The data in this directory is the intersection snp_mQTL pairs of GCST90044540 and the mQTL data obtained GoDMC database

This document describes the column headings of the result file

GWAS data section:
chr_pos = Chromosome_base pair position for the variant
variant_id = The rsid of the variant
effect_allele = The effect allele of the variant in GWAS data
other_allele = The non-effect allele in GWAS data
N = per allele sample size
effect_allele_frequency = Frequency of the effect allele in the control population
T = GLMM score statistic
SE_T = standard error of the score statistic
P_noSPA = raw p-value
beta = SNP effect or log(odds ratio)
standard_error = standard error for the estimated effect size after the SPA correction
p_value = p-value after the SPA correction
CONVERGE = to indicate whether the SPA correction is converged for the variant

mQTL data section:
cpg=450k cpg
type = The type of the variant
beta_a1 = Regression coefficient of allele 1 from fixed effects meta analysis
se = Standard error fixed effects meta analysis
pval = Pvalue fixed effects meta analysis
samplesize = Samplesize used in fixed effects meta analysis
allele1 = Effect allele
allele2 = Non effect allele
freq_a1 = Effect allele frequency
freq_se = Standard error allele frequency
cistrans = cis=TRUE, Cis = Distance between SNP-CpG <1 MB
num_studies = Number of studies used in fixed effects meta analysis
direction = Direction for each of 36 cohorts
hetisq = I2 
hetchisq = Heterogeneity Chi square
hetpval = Heterogeneity pvalue 
tausq = Tau square
beta_are_a1 = Regression coefficient of allele 1 from additive random effects meta analysis
se_are = Standard error additive random effects meta analysis
pval_are = Pvalue random effects meta analysis
se_mre = Standard error multiplicative random effects meta analysis; Effect sizes MRE are the same as in beta_a1 column
pval_mre = Pvalue multiplicative random effects meta analysis
chunk = meta analysis chunks
clumped = TRUE means index SNV