ONTOLOGY	ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	qvalue	geneID	Count
KEGG	hsa00510	N-Glycan biosynthesis	15/898	50/8144	0.0002102	0.03873	0.03654	ALG2/DPM1/TUSC3/ALG14/MAN2A1/MGAT5/STT3A/ALG12/ALG13/MAN1A1/DOLK/ALG1/RPN2/ST6GAL2/MOGS	15
KEGG	hsa04080	Neuroactive ligand-receptor interaction	62/898	362/8144	0.0002362	0.03873	0.03654	SST/HTR4/GRIK2/NTSR2/DRD2/NPY2R/NPY5R/GRM5/GLP1R/HTR6/MLNR/THRB/GRM1/ADRA1D/GAL/HTR2C/EDNRB/LPAR3/GABRA5/OPRK1/GRM6/EDNRA/GABRA4/PTH2R/NPY1R/TRH/PYY/NMS/TAAR8/PTGER3/TACR1/CHRM2/OPRM1/GLRA1/P2RX4/DRD5/GRM7/CHRND/GABRB3/TAC1/P2RX2/P2RY14/ADRA2C/HTR1E/QRFPR/CCK/GRP/UTS2/AGTR1/GRIN2A/GRIA4/CHRNA1/MCHR2/CALCR/GABRB1/MTNR1A/GABRG3/SSTR4/GLRB/ADRA1A/NPY/ADRB2	62
KEGG	hsa04350	TGF-beta signaling pathway	21/898	94/8144	0.001134	0.1152	0.1087	BMP8B/EP300/AMH/BMP7/ZFYVE16/CUL1/ACVR1B/NODAL/FST/BMPR1B/SMAD2/CHRD/ACVR2A/CREBBP/ZFYVE9/SMAD5/GREM1/BMP2/TGFB2/BMP4/PPP2R1B	21
KEGG	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	18/898	77/8144	0.00145	0.1152	0.1087	DSP/CDH2/SLC8A2/CACNG3/ACTN3/CTNNB1/ACTN2/ITGA10/CTNNA2/GJA1/JUP/ITGA8/CACNG8/CACNA1F/ITGA2/ITGB5/DES/LAMA2	18
KEGG	hsa04310	Wnt signaling pathway	31/898	167/8144	0.002388	0.1152	0.1087	WNT3/WIF1/CTNNB1/SENP2/RSPO4/EP300/FZD8/CSNK2A1/FRZB/FZD7/CTNND2/RSPO1/WNT9B/MAPK9/PRICKLE1/CUL1/FZD9/FZD3/SFRP1/SFRP5/TBL1X/PPP3CA/LGR5/WNT2B/WNT10B/WNT6/CREBBP/CXXC4/LGR4/FZD5/WNT8B	31
KEGG	hsa00513	Various types of N-glycan biosynthesis	11/898	39/8144	0.002516	0.1152	0.1087	ALG2/TUSC3/ALG14/MAN2A1/STT3A/CHST8/ALG12/ALG13/MAN1A1/ALG1/RPN2	11
KEGG	hsa05217	Basal cell carcinoma	15/898	63/8144	0.002904	0.1152	0.1087	WNT3/CTNNB1/PTCH1/FZD8/FZD7/WNT9B/FZD9/FZD3/WNT2B/WNT10B/WNT6/BMP2/FZD5/WNT8B/BMP4	15
KEGG	hsa05205	Proteoglycans in cancer	36/898	205/8144	0.003013	0.1152	0.1087	WNT3/CTNNB1/HPSE2/PTCH1/FZD8/FZD7/WNT9B/SOS2/AKT3/ERBB4/MTOR/FZD9/FZD3/MMP2/HSPB2/SOS1/CASP3/FLNB/TLR2/SMAD2/PPP1R12B/PDPK1/COL1A2/ITPR2/TIAM1/WNT2B/WNT10B/ITGA2/WNT6/ITGB5/GPC1/RRAS2/TGFB2/FZD5/WNT8B/FN1	36
KEGG	hsa05226	Gastric cancer	28/898	149/8144	0.00316	0.1152	0.1087	WNT3/CTNNB1/FGF8/FGF9/FZD8/ABCB1/FZD7/FGF5/FGF10/WNT9B/SOS2/AKT3/MTOR/CTNNA2/FZD9/FZD3/FGF4/SOS1/JUP/SMAD2/RARB/WNT2B/WNT10B/RB1/WNT6/TGFB2/FZD5/WNT8B	28
KEGG	hsa05224	Breast cancer	27/898	147/8144	0.005127	0.1682	0.1587	WNT3/ESR2/CTNNB1/FGF8/DLL1/CDK4/FGF9/FZD8/FZD7/FGF5/FGF10/WNT9B/SOS2/AKT3/PGR/MTOR/FZD9/FZD3/FGF4/SOS1/NOTCH2/WNT2B/WNT10B/RB1/WNT6/FZD5/WNT8B	27
KEGG	hsa04916	Melanogenesis	20/898	101/8144	0.006432	0.1833	0.173	WNT3/ADCY8/ADCY1/CTNNB1/KITLG/CALM1/EP300/EDNRB/FZD8/FZD7/WNT9B/FZD9/FZD3/WNT2B/WNT10B/WNT6/CREBBP/FZD5/WNT8B/GNAQ	20
KEGG	hsa04540	Gap junction	18/898	88/8144	0.006708	0.1833	0.173	ADCY8/DRD2/ADCY1/GRM5/CDK1/GRM1/TJP1/HTR2C/SOS2/TUBB2A/TUBB8/GJA1/SOS1/TUBB6/GJD2/ITPR2/GNA11/GNAQ	18
KEGG	hsa05168	Herpes simplex virus 1 infection	72/898	495/8144	0.007604	0.1919	0.181	HLA-DRB5/ZNF251/ZNF577/ZNF430/ZNF559/ZNF845/BID/ZNF83/ZIK1/ZNF3/ZNF429/ZNF347/ZNF33A/ZNF583/HLA-C/ZNF440/ZNF773/ZNF74/ZNF727/AKT3/MTOR/ZNF470/ZNF416/ZNF714/ZNF286A/HLA-DRB1/ZNF619/ZNF235/ZNF813/ZNF229/ZNF766/POU2F3/RHEB/ZFP30/ZNF708/ZNF230/ZNF426/ZNF561/IL6/ZNF530/CASP3/ZNF557/ZNF735/TLR2/ZNF223/ZNF662/ZNF90/ZNF492/ZNF248/ZNF441/ZNF547/ZNF778/ZNF334/ZNF699/ZNF484/ZNF45/ZFP82/ZNF611/ZNF585B/ZNF878/HCFC1/ZNF7/ZNF256/ZNF43/ZNF846/ZNF177/ZNF302/SOCS3/ZNF283/ZNF582/ZNF181/HLA-G	72
KEGG	hsa00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	7/898	24/8144	0.01243	0.2524	0.2381	HS2ST1/HS6ST3/HS3ST3A1/NDST4/GLCE/EXT2/HS3ST1	7
KEGG	hsa04550	Signaling pathways regulating pluripotency of stem cells	25/898	143/8144	0.01285	0.2524	0.2381	PCGF6/WNT3/CTNNB1/FZD8/FZD7/WNT9B/AKT3/FZD9/ACVR1B/FZD3/NODAL/MYF5/NEUROG1/BMPR1B/SMAD2/ACVR2A/TBX3/WNT2B/WNT10B/WNT6/SMAD5/FZD5/WNT8B/BMP4/ZIC3	25
KEGG	hsa05017	Spinocerebellar ataxia	25/898	143/8144	0.01285	0.2524	0.2381	AFG3L2/SLC25A4/FGF14/GRM1/TBPL2/TRPC3/OMA1/PSMD9/AKT3/MTOR/ATXN2L/MAPK9/PSMA8/RELN/ATXN3/ITPR2/ATG2B/PSMB5/GRIN2A/ULK2/ATXN8OS/ULK1/PSMA2/ATXN2/GNAQ	25
KEGG	hsa04020	Calcium signaling pathway	38/898	240/8144	0.01333	0.2524	0.2381	HTR4/ADCY8/SLC8A2/ADCY1/FGF8/GRM5/SLC25A4/HTR6/CALM1/GRM1/FGF9/ADRA1D/CAMK1D/HTR2C/EDNRB/EDNRA/FGF5/FGF10/ERBB4/FGF4/PTGER3/TACR1/CHRM2/P2RX4/DRD5/PHKB/P2RX2/ITPR2/PPP3CA/AGTR1/GNA11/CACNA1F/GRIN2A/ASPH/ADRA1A/GNAL/ADRB2/GNAQ	38
KEGG	hsa05022	Pathways of neurodegeneration - multiple diseases	68/898	476/8144	0.01385	0.2524	0.2381	GPX7/WNT3/BID/CTNNB1/GRM5/SLC25A4/DNAH11/CALM1/GRM1/DNAH7/TRPC3/FZD8/CSNK2A1/FZD7/BDNF/PSMD9/WNT9B/COX4I1/MTOR/ATXN2L/MAPK9/TUBB2A/NDUFS3/FZD9/RAB5A/PSMA8/FZD3/VAPB/DNAH6/IL6/TUBB8/CASP3/TUBB6/SNCAIP/ATXN3/ZFYVE1/HTT/ITPR2/PPP3CA/CHMP2B/WNT2B/ATG2B/PSMB5/ATF6/NDUFS7/NOX4/CACNA1F/WNT10B/GRIN2A/GRIA4/KIF5C/WNT6/MFN1/ULK2/DNALI1/KLC3/GPR37/DNAH9/KIF5B/ULK1/RAB39B/PSMA2/CAT/FZD5/WNT8B/ATXN2/DNAH1/GNAQ	68
KEGG	hsa04727	GABAergic synapse	17/898	89/8144	0.01623	0.2802	0.2643	ABAT/ADCY8/ADCY1/GABRA5/SLC6A11/GABRA4/GLS2/GABARAPL1/GNB4/GABRB3/GNB1/SLC6A1/CACNA1F/GAD2/GABRB1/GABRG3/GPHN	17
KEGG	hsa04150	mTOR signaling pathway	26/898	156/8144	0.02027	0.3226	0.3044	WNT3/PRKAA2/SLC38A9/FZD8/FZD7/WNT9B/SOS2/AKT3/MTOR/FZD9/FZD3/RHEB/WDR59/SOS1/PDPK1/STRADB/TBC1D7/WNT2B/WNT10B/WNT6/RRAGC/ULK2/SEH1L/ULK1/FZD5/WNT8B	26
KEGG	hsa04929	GnRH secretion	13/898	64/8144	0.02066	0.3226	0.3044	KCNN2/ESR2/KCNJ3/TRPC1/HCN1/AKT3/TRPC4/TRPC5/ITPR2/GNA11/CACNA1F/KCNJ11/GNAQ	13
KEGG	hsa04390	Hippo signaling pathway	26/898	157/8144	0.02184	0.3256	0.3072	WNT3/BMP8B/CTNNB1/AMH/BMP7/FZD8/FZD7/WNT9B/CTNNA2/FZD9/FZD3/BMPR1B/SMAD2/PARD6G/WNT2B/RASSF6/WNT10B/WNT6/AMOT/BMP2/TGFB2/FZD5/BIRC5/WNT8B/BMP4/PPP2R1B	26
KEGG	hsa04724	Glutamatergic synapse	20/898	114/8144	0.02349	0.335	0.3161	HOMER1/ADCY8/GRIK2/KCNJ3/ADCY1/GRM5/GRM1/TRPC1/GRM6/GLS2/GRM7/GNB4/SLC17A8/ITPR2/PPP3CA/GNB1/GRIN2A/GRIA4/DLGAP1/GNAQ	20
KEGG	hsa04024	cAMP signaling pathway	34/898	221/8144	0.02732	0.3733	0.3522	SST/HTR4/ADCY8/DRD2/ADCY1/GLP1R/HTR6/CALM1/EP300/AMH/PDE3A/PTCH1/ADCY10/EDNRA/TNNI3/BDNF/AKT3/NPY1R/MAPK9/PTGER3/CHRM2/DRD5/TIAM1/PDE4C/HTR1E/RAP1B/CACNA1F/GRIN2A/ATP1B2/GRIA4/CREBBP/RRAS2/NPY/ADRB2	34
KEGG	hsa04512	ECM-receptor interaction	16/898	88/8144	0.02968	0.3895	0.3675	LAMC2/FREM2/NPNT/CHAD/ITGA10/RELN/COL4A5/COL1A2/ITGA8/ITGA2/GP1BB/ITGB5/COL4A6/SV2C/LAMA2/FN1	16
KEGG	hsa03460	Fanconi anemia pathway	11/898	54/8144	0.0312	0.3937	0.3714	RMI1/RPA1/FANCF/PMS2/POLN/FANCC/FANCI/RPA2/FANCG/USP1/POLH	11
KEGG	hsa04141	Protein processing in endoplasmic reticulum	27/898	171/8144	0.03427	0.4041	0.3813	CKAP4/UGGT2/NGLY1/SEC61B/SEC23A/CRYAB/DNAJC10/SVIP/TRAM1L1/TUSC3/MAPK9/CUL1/STT3A/DNAJC1/DNAJB1/ATXN3/DNAJC3/MAN1A1/HSPA2/ATF6/MBTPS2/YOD1/SSR1/RPN2/MOGS/UBE2D2/SEC61A2	27
KEGG	hsa00515	Mannose type O-glycan biosynthesis	6/898	23/8144	0.0345	0.4041	0.3813	FUT9/B3GAT1/FKTN/B3GAT2/POMT2/CHST10	6
KEGG	hsa05410	Hypertrophic cardiomyopathy	16/898	90/8144	0.03579	0.4048	0.382	SLC8A2/CACNG3/PRKAB2/ACTC1/PRKAA2/ITGA10/TNNI3/IL6/ITGA8/CACNG8/CACNA1F/ITGA2/ITGB5/DES/LAMA2/TGFB2	16
KEGG	hsa00512	Mucin type O-glycan biosynthesis	8/898	36/8144	0.03893	0.4256	0.4016	GALNT11/B3GNT6/GALNT7/C1GALT1/GCNT1/GALNT13/GALNTL6/GALNT2	8
KEGG	hsa00310	Lysine degradation	12/898	63/8144	0.0403	0.4264	0.4023	SETMAR/SMYD3/SMYD2/PRDM6/MECOM/AASS/PRDM9/EZH1/AADAT/EHMT1/PLOD2/ALDH3A2	12
KEGG	hsa04933	AGE-RAGE signaling pathway in diabetic complications	17/898	100/8144	0.04539	0.4577	0.4319	CDK4/AKT3/MAPK9/MMP2/IL6/CASP3/F3/COL4A5/SMAD2/COL1A2/NOX4/AGTR1/COL4A6/FOXO1/COL3A1/TGFB2/FN1	17
KEGG	hsa05225	Hepatocellular carcinoma	26/898	168/8144	0.04605	0.4577	0.4319	WNT3/CTNNB1/CDK4/ACTL6B/SMARCE1/FZD8/FZD7/WNT9B/SOS2/AKT3/MTOR/FZD9/SMARCC2/FZD3/SOS1/SMAD2/ARID1A/WNT2B/WNT10B/RB1/WNT6/SMARCC1/TGFB2/FZD5/WNT8B/DPF3	26
KEGG	hsa04710	Circadian rhythm	7/898	31/8144	0.048	0.4631	0.4369	PRKAB2/PRKAA2/CLOCK/CUL1/PER2/CRY1/RORB	7
KEGG	hsa05146	Amoebiasis	17/898	102/8144	0.05327	0.4867	0.4592	LAMC2/ADCY1/RAB5A/IL6/CASP3/TLR2/COL4A5/COL1A2/ACTN1/GNA11/COL4A6/LAMA2/COL3A1/TGFB2/GNAL/FN1/GNAQ	17
KEGG	hsa04934	Cushing syndrome	24/898	155/8144	0.05342	0.4867	0.4592	WNT3/ADCY8/KCNK2/ADCY1/CTNNB1/CDK4/FZD8/FZD7/WNT9B/FZD9/FZD3/KCNA4/ITPR2/WNT2B/RAP1B/AGTR1/GNA11/CACNA1F/WNT10B/RB1/WNT6/FZD5/WNT8B/GNAQ	24
KEGG	hsa04720	Long-term potentiation	12/898	67/8144	0.0605	0.5304	0.5004	ADCY8/ADCY1/GRM5/CALM1/EP300/GRM1/ITPR2/PPP3CA/RAP1B/GRIN2A/CREBBP/GNAQ	12
KEGG	hsa04211	Longevity regulating pathway	15/898	89/8144	0.06145	0.5304	0.5004	ADCY8/KL/ADCY1/SESN3/PRKAB2/PRKAA2/ADIPOR1/IRS2/AKT3/MTOR/RHEB/EHMT1/ULK1/FOXO1/CAT	15
KEGG	hsa05033	Nicotine addiction	8/898	40/8144	0.06709	0.5497	0.5187	GABRA5/GABRA4/GABRB3/SLC17A8/GRIN2A/GRIA4/GABRB1/GABRG3	8
KEGG	hsa00514	Other types of O-glycan biosynthesis	9/898	47/8144	0.06819	0.5497	0.5187	GALNT11/GALNT7/C1GALT1/GALNT13/GALNTL6/GALNT2/POMT2/POFUT2/ST6GAL2	9
KEGG	hsa04022	cGMP-PKG signaling pathway	25/898	167/8144	0.06872	0.5497	0.5187	ADCY8/SLC8A2/ADCY1/SLC25A4/CALM1/GATA4/PDE3A/ADRA1D/EDNRB/EDNRA/IRS2/AKT3/ITPR2/PPP3CA/ADRA2C/AGTR1/GNA11/CACNA1F/ATP1B2/KCNMB3/MEF2A/KCNMB4/ADRA1A/ADRB2/GNAQ	25
KEGG	hsa04920	Adipocytokine signaling pathway	12/898	69/8144	0.07276	0.5673	0.5353	CPT1C/PRKAB2/PRKAA2/ADIPOR1/ACSL6/IRS2/AKT3/MTOR/MAPK9/ACSL1/SOCS3/NPY	12
KEGG	hsa04213	Longevity regulating pathway - multiple species	11/898	62/8144	0.07438	0.5673	0.5353	ADCY8/ADCY1/PRKAB2/PRKAA2/IRS2/CRYAB/AKT3/MTOR/HSPA2/FOXO1/CAT	11
KEGG	hsa04726	Serotonergic synapse	18/898	115/8144	0.07894	0.5884	0.5552	HTR4/KCNN2/KCNJ3/HTR6/TRPC1/HTR2C/KCND2/CASP3/ALOX15/GNB4/GABRB3/ITPR2/HTR1E/GNB1/CACNA1F/SLC6A4/GABRB1/GNAQ	18
KEGG	hsa04911	Insulin secretion	14/898	86/8144	0.08708	0.6347	0.5989	KCNN2/ADCY8/ADCY1/GLP1R/PCLO/RIMS2/CCK/GNA11/CACNA1F/ATP1B2/KCNJ11/KCNMB3/KCNMB4/GNAQ	14
KEGG	hsa04935	Growth hormone synthesis, secretion and action	18/898	119/8144	0.1018	0.7211	0.6803	SST/ADCY8/ADCY1/EP300/ADCY10/IRS2/SOS2/AKT3/MTOR/MAPK9/SOS1/ITPR2/GNA11/CACNA1F/MAP2K4/CREBBP/SOCS3/GNAQ	18
KEGG	hsa05414	Dilated cardiomyopathy	15/898	96/8144	0.1033	0.7211	0.6803	ADCY8/SLC8A2/ADCY1/CACNG3/ACTC1/ITGA10/TNNI3/ITGA8/CACNG8/CACNA1F/ITGA2/ITGB5/DES/LAMA2/TGFB2	15
KEGG	hsa00250	Alanine, aspartate and glutamate metabolism	7/898	37/8144	0.1063	0.7233	0.6824	ABAT/NAT8L/GLUD2/GLS2/FOLH1/IL4I1/GAD2	7
KEGG	hsa04152	AMPK signaling pathway	18/898	120/8144	0.108	0.7233	0.6824	CPT1C/PRKAB2/PRKAA2/ADIPOR1/IRS2/AKT3/MTOR/RHEB/HMGCR/PDPK1/STRADB/RAB2A/SCD/PPP2R3C/ULK1/FOXO1/ADRA1A/PPP2R1B	18
KEGG	hsa04146	Peroxisome	13/898	82/8144	0.1133	0.7337	0.6923	PEX3/SCP2/PEX7/ACSL6/HMGCLL1/PEX5L/PEX11B/ACSL1/PEX1/EPHX2/NUDT12/AGPS/CAT	13
KEGG	hsa04919	Thyroid hormone signaling pathway	18/898	121/8144	0.1146	0.7337	0.6923	MED13L/CTNNB1/THRB/EP300/GATA4/SLC16A10/AKT3/MTOR/RHEB/MED14/NOTCH2/PDPK1/NCOR1/ATP1B2/CREBBP/MED27/FOXO1/BMP4	18
KEGG	hsa03022	Basal transcription factors	8/898	45/8144	0.1163	0.7337	0.6923	GTF2H5/TAF7L/TAF7/TAF3/TBPL2/TAF11/TAF6/TAF1L	8
KEGG	hsa05032	Morphine addiction	14/898	91/8144	0.1238	0.7664	0.7232	ADCY8/KCNJ3/ADCY1/PDE3A/GABRA5/GABRA4/PDE7B/OPRM1/GNB4/GABRB3/PDE4C/GNB1/GABRB1/GABRG3	14
KEGG	hsa04068	FoxO signaling pathway	19/898	131/8144	0.1286	0.7804	0.7363	HOMER1/PLK2/EP300/GRM1/PRKAB2/PRKAA2/IRS2/SOS2/AKT3/MAPK9/IL6/GABARAPL1/SOS1/PDPK1/BCL2L11/CREBBP/FOXO1/CAT/TGFB2	19
KEGG	hsa04218	Cellular senescence	22/898	156/8144	0.1347	0.7804	0.7363	SLC25A4/CDK1/HIPK2/CALM1/CDK4/GATA4/HLA-C/AKT3/MTOR/MYBL2/RHEB/IL6/SMAD2/RAD1/ITPR2/PPP3CA/RB1/NBN/FOXO1/RRAS2/TGFB2/HLA-G	22
KEGG	hsa04723	Retrograde endocannabinoid signaling	21/898	148/8144	0.1352	0.7804	0.7363	ADCY8/KCNJ3/ADCY1/GRM5/GRM1/GABRA5/GABRA4/MAPK9/NDUFS3/GNB4/GABRB3/SLC17A8/ITPR2/GNB1/NDUFS7/CACNA1F/NAPEPLD/GRIA4/GABRB1/GABRG3/GNAQ	21
KEGG	hsa04728	Dopaminergic synapse	19/898	132/8144	0.1356	0.7804	0.7363	KCNJ3/DRD2/CALM1/CLOCK/AKT3/MAPK9/DRD5/GNB4/ITPR2/PPP3CA/GNB1/GRIN2A/GRIA4/KIF5C/PPP2R3C/KIF5B/GNAL/PPP2R1B/GNAQ	19
KEGG	hsa05165	Human papillomavirus infection	43/898	331/8144	0.1416	0.7921	0.7473	WNT3/LAMC2/CTNNB1/EP300/CDK4/CHAD/HES4/TBPL2/ITGA10/HLA-C/FZD8/FZD7/WNT9B/SOS2/AKT3/MTOR/FZD9/FZD3/RHEB/SOS1/CASP3/RELN/NOTCH2/COL4A5/COL1A2/ITGA8/PARD6G/WNT2B/WNT10B/ITGA2/RB1/WNT6/ITGB5/PPP2R3C/CREBBP/COL4A6/FOXO1/LAMA2/FZD5/WNT8B/FN1/PPP2R1B/HLA-G	43
KEGG	hsa04140	Autophagy - animal	20/898	141/8144	0.1425	0.7921	0.7473	MTMR14/PRKAA2/IRS2/AKT3/MTOR/MAPK9/RHEB/MTMR3/GABARAPL1/PDPK1/ZFYVE1/ATG3/ATG2B/RRAGC/ULK2/ULK1/RAB39B/RRAS2/RAB33B/DAPK1	20
KEGG	hsa00531	Glycosaminoglycan degradation	4/898	19/8144	0.1497	0.8015	0.7563	HPSE2/SGSH/GNS/IDUA	4
KEGG	hsa05132	Salmonella infection	33/898	249/8144	0.1502	0.8015	0.7563	DYNLT1/RHOB/PODXL/CTNNB1/EXOC7/GCC2/ARPC1A/AKT3/MAPK9/TUBB2A/RAB9B/RAB5A/IL6/TUBB8/CASP3/TUBB6/FLNB/TLR2/ACBD3/PFN3/DYNLRB2/RAB9A/DYNC1LI1/KIF5C/MAP2K4/PAK3/KLC3/MYO6/KIF5B/EXOC4/DNM2/VPS16/EXOC5	33
KEGG	hsa00563	Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	5/898	26/8144	0.1515	0.8015	0.7563	PIGZ/PIGK/PGAP1/PIGH/PIGU	5
KEGG	hsa04520	Adherens junction	11/898	71/8144	0.1542	0.8029	0.7575	CTNNB1/EP300/TJP1/CSNK2A1/CTNNA2/SSX2IP/PTPRB/YES1/ACTN1/CREBBP/PTPRM	11
KEGG	hsa04974	Protein digestion and absorption	15/898	103/8144	0.1592	0.816	0.77	SLC8A2/SLC15A1/COL21A1/COL12A1/CPA2/SLC16A10/COL5A2/COL25A1/COL4A5/COL1A2/SLC7A8/SLC7A9/ATP1B2/COL4A6/COL3A1	15
KEGG	hsa01040	Biosynthesis of unsaturated fatty acids	5/898	27/8144	0.1702	0.8586	0.8101	ELOVL2/SCP2/HSD17B12/SCD/FADS1	5
KEGG	hsa04979	Cholesterol metabolism	8/898	50/8144	0.1804	0.8964	0.8458	LPL/SOAT1/PCSK9/ABCA1/NPC2/VAPB/LDLRAP1/ANGPTL4	8
KEGG	hsa01522	Endocrine resistance	14/898	98/8144	0.188	0.9206	0.8686	ADCY8/ESR2/ADCY1/DLL1/CDK4/SOS2/AKT3/MTOR/MAPK9/MMP2/SOS1/NOTCH2/NCOR1/RB1	14
KEGG	hsa05010	Alzheimer disease	48/898	384/8144	0.1932	0.9318	0.8791	LPL/WNT3/BID/CTNNB1/GRM5/SLC25A4/SLC39A8/CALM1/FZD8/CSNK2A1/FZD7/IRS2/PSMD9/WNT9B/COX4I1/AKT3/MTOR/MAPK9/TUBB2A/NDUFS3/FZD9/PSMA8/FZD3/IL6/TUBB8/CASP3/TUBB6/ITPR2/PPP3CA/WNT2B/ATG2B/PSMB5/ATF6/NDUFS7/NOX4/CACNA1F/WNT10B/GRIN2A/KIF5C/WNT6/ULK2/KLC3/KIF5B/ULK1/PSMA2/FZD5/WNT8B/GNAQ	48
KEGG	hsa04922	Glucagon signaling pathway	15/898	107/8144	0.1971	0.937	0.8841	LDHC/CPT1C/CALM1/EP300/PRKAB2/PRKAA2/AKT3/SIK1/PHKB/ITPR2/SIK2/PPP3CA/CREBBP/FOXO1/GNAQ	15
KEGG	hsa04360	Axon guidance	24/898	182/8144	0.2028	0.9505	0.8968	PAK2/EPHA3/NTNG1/TRPC1/SLIT2/TRPC3/BMP7/LRRC4C/PTCH1/EPHA1/TRPC4/SEMA6A/EPHA4/FZD3/BMPR1B/TRPC5/PDPK1/PARD6G/PPP3CA/SEMA6C/PAK3/RND1/SLIT1/SEMA6D	24
KEGG	hsa04261	Adrenergic signaling in cardiomyocytes	20/898	150/8144	0.2141	0.986	0.9303	ADCY8/SLC8A2/ADCY1/CACNG3/CALM1/ACTC1/ADRA1D/TNNI3/AKT3/RPS6KA5/CACNG8/AGTR1/CACNA1F/ATP1B2/PPP2R3C/ADRA1A/SCN4B/PPP2R1B/ADRB2/GNAQ	20
KEGG	hsa04270	Vascular smooth muscle contraction	18/898	134/8144	0.2198	0.986	0.9303	ADCY8/ADCY1/CALM1/ADRA1D/EDNRA/PPP1R14A/PLA2G10/PPP1R12B/ITPR2/MYH10/AGTR1/GNA11/CACNA1F/KCNMB3/KCNMB4/ADRA1A/CALD1/GNAQ	18
KEGG	hsa04510	Focal adhesion	26/898	201/8144	0.2198	0.986	0.9303	PAK2/LAMC2/CTNNB1/CHAD/ITGA10/SOS2/AKT3/MAPK9/SOS1/FLNB/RELN/COL4A5/PPP1R12B/PDPK1/COL1A2/ITGA8/ACTN1/PIP5K1B/RAP1B/ITGA2/ITGB5/PAK3/PARVA/COL4A6/LAMA2/FN1	26
KEGG	hsa04924	Renin secretion	10/898	69/8144	0.2255	0.986	0.9303	CALM1/PDE3A/EDNRA/KCNJ2/ITPR2/PPP3CA/AGTR1/CACNA1F/ADRB2/GNAQ	10
KEGG	hsa05211	Renal cell carcinoma	10/898	69/8144	0.2255	0.986	0.9303	PAK2/EP300/SOS2/AKT3/SOS1/EGLN3/RAP1B/PAK3/CREBBP/TGFB2	10
KEGG	hsa00230	Purine metabolism	17/898	128/8144	0.2426	1	0.9435	ADCY8/ADCY1/NUDT9/PDE3A/NT5C1B/GDA/ADCY10/NT5C2/PDE7B/ENPP4/PDE4C/ITPA/PDE9A/PAPSS2/ENTPD6/NUDT16/GUCY2D	17
KEGG	hsa03430	Mismatch repair	4/898	23/8144	0.2437	1	0.9435	RPA1/PMS2/RPA2/RFC1	4
KEGG	hsa04964	Proximal tubule bicarbonate reclamation	4/898	23/8144	0.2437	1	0.9435	GLUD2/GLS2/MDH1/ATP1B2	4
KEGG	hsa00410	beta-Alanine metabolism	5/898	31/8144	0.2522	1	0.9435	ABAT/DPYS/GAD2/GADL1/ALDH3A2	5
KEGG	hsa00430	Taurine and hypotaurine metabolism	3/898	16/8144	0.2556	1	0.9435	CDO1/GAD2/GADL1	3
KEGG	hsa04725	Cholinergic synapse	15/898	113/8144	0.2609	1	0.9435	ADCY8/KCNJ3/ADCY1/SLC5A7/AKT3/KCNJ2/KCNQ5/CHRM2/GNB4/ITPR2/CHAT/GNB1/GNA11/CACNA1F/GNAQ	15
KEGG	hsa04137	Mitophagy - animal	10/898	72/8144	0.2672	1	0.9435	NBR1/CSNK2A1/FUNDC1/MAPK9/TOMM7/GABARAPL1/RHOT1/MFN1/ULK1/RRAS2	10
KEGG	hsa04713	Circadian entrainment	13/898	97/8144	0.2692	1	0.9435	ADCY8/KCNJ3/ADCY1/CALM1/ADCY10/PER2/GNB4/RPS6KA5/GNB1/GRIN2A/GRIA4/MTNR1A/GNAQ	13
KEGG	hsa04923	Regulation of lipolysis in adipocytes	8/898	56/8144	0.2728	1	0.9435	ADCY8/ADCY1/IRS2/AKT3/NPY1R/PTGER3/NPY/ADRB2	8
KEGG	hsa04114	Oocyte meiosis	17/898	131/8144	0.2738	1	0.9435	ADCY8/ADCY1/SMC1A/MOS/CDK1/CALM1/MAD2L1/PGR/CUL1/CPEB1/STAG3/ITPR2/PPP3CA/SMC3/MAD1L1/PPP2R1B/SLK	17
KEGG	hsa04136	Autophagy - other	5/898	32/8144	0.2741	1	0.9435	MTOR/GABARAPL1/ATG3/ATG2B/ULK2	5
KEGG	hsa04215	Apoptosis - multiple species	5/898	32/8144	0.2741	1	0.9435	BID/MAPK9/CASP3/BCL2L11/BIRC5	5
KEGG	hsa04072	Phospholipase D signaling pathway	19/898	148/8144	0.2744	1	0.9435	ADCY8/DGKG/ADCY1/GRM5/KITLG/GRM1/LPAR3/GRM6/SOS2/AKT3/MTOR/RHEB/SOS1/GRM7/PIP5K1B/AGTR1/DGKH/DNM2/RRAS2	19
KEGG	hsa05014	Amyotrophic lateral sclerosis	44/898	364/8144	0.2778	1	0.9435	GPX7/BID/DNAH11/DNAH7/PSMD9/COX4I1/ERBB4/NRG1/MTOR/ATXN2L/NUP188/TUBB2A/NDUFS3/RAB5A/PSMA8/NUP37/VAPB/DNAH6/TUBB8/CASP3/TUBB6/NUP62/PFN3/PPP3CA/CHMP2B/ATG2B/PSMB5/ATF6/NDUFS7/GRIN2A/KIF5C/ULK2/DNALI1/HDAC6/KLC3/SEH1L/DNAH9/KIF5B/ULK1/RAB39B/PSMA2/CAT/ATXN2/DNAH1	44
KEGG	hsa04927	Cortisol synthesis and secretion	9/898	65/8144	0.2856	1	0.9435	ADCY8/KCNK2/ADCY1/KCNA4/ITPR2/AGTR1/GNA11/CACNA1F/GNAQ	9
KEGG	hsa04810	Regulation of actin cytoskeleton	27/898	218/8144	0.2882	1	0.9435	PAK2/ARHGEF7/MOS/FGF8/FGF9/DIAPH3/ARPC1A/ITGA10/FGF5/FGF10/SOS2/FGF4/SOS1/CHRM2/PFN3/PPP1R12B/ITGA8/MYH10/ACTN1/TIAM1/PIP5K1B/ITGA2/ITGB5/PAK3/RRAS2/ARHGEF4/FN1	27
KEGG	hsa01212	Fatty acid metabolism	8/898	57/8144	0.2893	1	0.9435	CPT1C/ELOVL2/SCP2/ACSL6/ACSL1/HSD17B12/SCD/FADS1	8
KEGG	hsa04216	Ferroptosis	6/898	41/8144	0.2952	1	0.9435	SLC39A8/ACSL6/GCLC/ACSL1/ALOX15/LPCAT3	6
KEGG	hsa05219	Bladder cancer	6/898	41/8144	0.2952	1	0.9435	CDK4/MMP2/RPS6KA5/RB1/DAPK1/UPK3A	6
KEGG	hsa00920	Sulfur metabolism	2/898	10/8144	0.3038	1	0.9435	ETHE1/PAPSS2	2
KEGG	hsa00240	Pyrimidine metabolism	8/898	58/8144	0.3062	1	0.9435	CMPK2/NT5C1B/NT5C2/CMPK1/TYMS/CTPS2/DPYS/ENTPD6	8
KEGG	hsa03320	PPAR signaling pathway	10/898	75/8144	0.3111	1	0.9435	LPL/CPT1C/SCP2/ME1/ACSL6/ACSL1/PDPK1/SCD/ANGPTL4/PLIN5	10
KEGG	hsa04110	Cell cycle	16/898	126/8144	0.3125	1	0.9435	DBF4/SMC1A/CDK1/EP300/CDK4/MAD2L1/CUL1/TFDP2/SMAD2/SMC3/RB1/WEE2/CREBBP/STAG1/MAD1L1/TGFB2	16
KEGG	hsa04971	Gastric acid secretion	10/898	76/8144	0.3261	1	0.9435	SST/ADCY8/KCNK2/ADCY1/CALM1/KCNJ2/ITPR2/ATP1B2/KCNK10/GNAQ	10
KEGG	hsa04912	GnRH signaling pathway	12/898	93/8144	0.3266	1	0.9435	ADCY8/ADCY1/CALM1/SOS2/MAPK9/MMP2/SOS1/ITPR2/GNA11/CACNA1F/MAP2K4/GNAQ	12
KEGG	hsa05142	Chagas disease	13/898	102/8144	0.3328	1	0.9435	CCL3/ADCY1/AKT3/MAPK9/IL6/TLR2/SMAD2/GNA11/MAP2K4/TGFB2/GNAL/PPP2R1B/GNAQ	13
KEGG	hsa04940	Type I diabetes mellitus	6/898	43/8144	0.3357	1	0.9435	HLA-DRB5/HLA-C/HLA-DRB1/HSPD1/GAD2/HLA-G	6
KEGG	hsa04926	Relaxin signaling pathway	16/898	129/8144	0.3474	1	0.9435	ADCY8/ADCY1/EDNRB/SOS2/AKT3/MAPK9/MMP2/SOS1/GNB4/COL4A5/SMAD2/COL1A2/GNB1/MAP2K4/COL4A6/COL3A1	16
KEGG	hsa05210	Colorectal cancer	11/898	86/8144	0.3481	1	0.9435	CTNNB1/SOS2/AKT3/MTOR/MAPK9/SOS1/CASP3/SMAD2/BCL2L11/TGFB2/BIRC5	11
KEGG	hsa04915	Estrogen signaling pathway	17/898	138/8144	0.3513	1	0.9435	ADCY8/ESR2/KCNJ3/ADCY1/CALM1/GRM1/SOS2/AKT3/PGR/MMP2/SOS1/OPRM1/KRT19/ITPR2/HSPA2/FKBP5/GNAQ	17
KEGG	hsa00561	Glycerolipid metabolism	8/898	61/8144	0.3577	1	0.9435	LPL/DGKG/PNPLA3/GPAM/LIPF/DGKH/GPAT2/ALDH3A2	8
KEGG	hsa04371	Apelin signaling pathway	17/898	139/8144	0.3628	1	0.9435	ADCY8/SLC8A2/ADCY1/CALM1/PRKAB2/PRKAA2/ADCY10/AKT3/MTOR/GNB4/SMAD2/ITPR2/GNB1/AGTR1/MEF2A/RRAS2/GNAQ	17
KEGG	hsa05016	Huntington disease	36/898	306/8144	0.3643	1	0.9435	GPX7/GRM5/SLC25A4/DNAH11/EP300/DNAH7/TBPL2/BDNF/PSMD9/COX4I1/MTOR/MAPK9/TUBB2A/NDUFS3/PSMA8/DNAH6/TUBB8/CASP3/TUBB6/AP2M1/HTT/ATG2B/PSMB5/NDUFS7/GRIA4/KIF5C/CREBBP/ULK2/DNALI1/KLC3/DNAH9/KIF5B/ULK1/PSMA2/DNAH1/GNAQ	36
KEGG	hsa03030	DNA replication	5/898	36/8144	0.3646	1	0.9435	RPA1/RPA2/POLE2/DNA2/RFC1	5
KEGG	hsa04961	Endocrine and other factor-regulated calcium reabsorption	7/898	53/8144	0.3668	1	0.9435	SLC8A2/KL/CALB1/AP2M1/ATP1B2/DNM2/GNAQ	7
KEGG	hsa00650	Butanoate metabolism	4/898	28/8144	0.3733	1	0.9435	ABAT/OXCT2/HMGCLL1/GAD2	4
KEGG	hsa04514	Cell adhesion molecules	18/898	149/8144	0.3772	1	0.9435	HLA-DRB5/CDH2/CNTNAP1/NCAM1/NTNG1/JAM2/LRRC4C/HLA-C/HLA-DRB1/CDH3/VCAN/SELP/CLDN5/ITGA8/NLGN4X/PVR/PTPRM/HLA-G	18
KEGG	hsa00100	Steroid biosynthesis	3/898	20/8144	0.3818	1	0.9435	SOAT1/CYP24A1/LSS	3
KEGG	hsa04930	Type II diabetes mellitus	6/898	46/8144	0.3973	1	0.9435	IRS2/MTOR/MAPK9/HK1/KCNJ11/SOCS3	6
KEGG	hsa05223	Non-small cell lung cancer	9/898	72/8144	0.3982	1	0.9435	CDK4/SOS2/AKT3/SOS1/PDPK1/RARB/KIF5C/RB1/KIF5B	9
KEGG	hsa03013	Nucleocytoplasmic transport	13/898	108/8144	0.4127	1	0.9435	SUMO1/SENP2/NMD3/NUP188/NUP37/IPO11/TNPO1/XPOT/NUP62/TNPO2/SEH1L/DDX19A/RANBP17	13
KEGG	hsa00770	Pantothenate and CoA biosynthesis	3/898	21/8144	0.4129	1	0.9435	DPYS/GADL1/ALDH3A2	3
KEGG	hsa03420	Nucleotide excision repair	6/898	47/8144	0.4178	1	0.9435	GTF2H5/RPA1/ERCC6/RPA2/POLE2/RFC1	6
KEGG	hsa01523	Antifolate resistance	4/898	30/8144	0.4254	1	0.9435	ABCC5/TYMS/ABCC2/IL6	4
KEGG	hsa05222	Small cell lung cancer	11/898	92/8144	0.436	1	0.9435	LAMC2/CDK4/AKT3/CASP3/COL4A5/RARB/ITGA2/RB1/COL4A6/LAMA2/FN1	11
KEGG	hsa04910	Insulin signaling pathway	16/898	137/8144	0.4433	1	0.9435	EXOC7/CALM1/PRKAB2/PRKAA2/IRS2/SOS2/AKT3/MTOR/MAPK9/RHEB/SOS1/PDPK1/PHKB/HK1/FOXO1/SOCS3	16
KEGG	hsa00220	Arginine biosynthesis	3/898	22/8144	0.4435	1	0.9435	GLUD2/NAGS/GLS2	3
KEGG	hsa00900	Terpenoid backbone biosynthesis	3/898	22/8144	0.4435	1	0.9435	IDI2/HMGCR/PDSS1	3
KEGG	hsa04015	Rap1 signaling pathway	24/898	210/8144	0.4585	1	0.9435	ADCY8/DRD2/ADCY1/CTNNB1/FGF8/PRKD1/KITLG/CALM1/FGF9/MAGI3/LPAR3/FGF5/FGF10/AKT3/RGS14/FGF4/PFN3/SIPA1L1/PARD6G/TIAM1/RAP1B/GRIN2A/RAP1GAP/GNAQ	24
KEGG	hsa04151	PI3K-Akt signaling pathway	40/898	354/8144	0.4596	1	0.9435	LAMC2/FGF8/KITLG/CDK4/CHAD/FGF9/PRKAA2/LPAR3/ITGA10/FGF5/BDNF/FGF10/SOS2/AKT3/ERBB4/MTOR/RHEB/FGF4/IL6/SOS1/CHRM2/RELN/TLR2/GNB4/COL4A5/PDPK1/COL1A2/ITGA8/GNB1/ITGA2/IL7/ITGB5/BCL2L11/PHLPP2/PPP2R3C/COL4A6/LAMA2/FN1/PPP2R1B/PKN2	40
KEGG	hsa01232	Nucleotide metabolism	10/898	85/8144	0.4645	1	0.9435	CMPK2/NT5C1B/GDA/NT5C2/CMPK1/TYMS/CTPS2/ITPA/ENTPD6/NUDT16	10
KEGG	hsa04012	ErbB signaling pathway	10/898	85/8144	0.4645	1	0.9435	PAK2/SOS2/AKT3/ERBB4/NRG1/MTOR/MAPK9/SOS1/MAP2K4/PAK3	10
KEGG	hsa04614	Renin-angiotensin system	3/898	23/8144	0.4735	1	0.9435	AGTR1/ENPEP/ATP6AP2	3
KEGG	hsa00640	Propanoate metabolism	4/898	32/8144	0.4763	1	0.9435	ABAT/LDHC/ACSS3/SUCLA2	4
KEGG	hsa05167	Kaposi sarcoma-associated herpesvirus infection	22/898	194/8144	0.4785	1	0.9435	BID/CTNNB1/CALM1/EP300/CDK4/HLA-C/AKT3/MTOR/MAPK9/MICA/IL6/CASP3/GNB4/ITPR2/ATG3/PPP3CA/GNB1/RB1/MAP2K4/CLEC2B/CREBBP/HLA-G	22
KEGG	hsa05416	Viral myocarditis	7/898	60/8144	0.4976	1	0.9435	HLA-DRB5/BID/HLA-C/HLA-DRB1/CASP3/LAMA2/HLA-G	7
KEGG	hsa00270	Cysteine and methionine metabolism	6/898	51/8144	0.4986	1	0.9435	BHMT/LDHC/CDO1/MDH1/GCLC/IL4I1	6
KEGG	hsa00380	Tryptophan metabolism	5/898	42/8144	0.4997	1	0.9435	CYP1B1/IL4I1/AADAT/CAT/ALDH3A2	5
KEGG	hsa05332	Graft-versus-host disease	5/898	42/8144	0.4997	1	0.9435	HLA-DRB5/HLA-C/HLA-DRB1/IL6/HLA-G	5
KEGG	hsa04977	Vitamin digestion and absorption	3/898	24/8144	0.5027	1	0.9435	SLC19A2/SLC19A3/FOLH1	3
KEGG	hsa00604	Glycosphingolipid biosynthesis - ganglio series	2/898	15/8144	0.5046	1	0.9435	B4GALNT1/ST6GALNAC5	2
KEGG	hsa00071	Fatty acid degradation	5/898	43/8144	0.5213	1	0.9435	CPT1C/ACSL6/ACSL1/ADH1A/ALDH3A2	5
KEGG	hsa04925	Aldosterone synthesis and secretion	11/898	98/8144	0.523	1	0.9435	ADCY8/ADCY1/PRKD1/CALM1/CAMK1D/ITPR2/AGTR1/GNA11/CACNA1F/ATP1B2/GNAQ	11
KEGG	hsa05231	Choline metabolism in cancer	11/898	98/8144	0.523	1	0.9435	DGKG/SLC5A7/SOS2/AKT3/MTOR/MAPK9/RHEB/SOS1/PDPK1/PIP5K1B/DGKH	11
KEGG	hsa04931	Insulin resistance	12/898	108/8144	0.5347	1	0.9435	PRKAB2/PRKAA2/IRS2/AKT3/MTOR/MAPK9/IL6/MLXIPL/PDPK1/TRIB3/FOXO1/SOCS3	12
KEGG	hsa05218	Melanoma	8/898	72/8144	0.5468	1	0.9435	FGF8/CDK4/FGF9/FGF5/FGF10/AKT3/FGF4/RB1	8
KEGG	hsa04950	Maturity onset diabetes of the young	3/898	26/8144	0.5585	1	0.9435	NEUROD1/HNF1B/NKX2-2	3
KEGG	hsa02010	ABC transporters	5/898	45/8144	0.5632	1	0.9435	ABCB1/ABCA5/ABCC5/ABCA1/ABCC2	5
KEGG	hsa05207	Chemical carcinogenesis - receptor activation	23/898	212/8144	0.5667	1	0.9435	ADCY8/ESR2/ADCY1/FGF8/DLL1/FGF9/FGF5/FGF10/SOS2/AKT3/PGR/MTOR/FGF4/SOS1/NOTCH2/CYP1B1/EPHX2/CACNA1F/PAQR8/RB1/KLF5/BIRC5/ADRB2	23
KEGG	hsa00350	Tyrosine metabolism	4/898	36/8144	0.5722	1	0.9435	GSTZ1/PNMT/IL4I1/ADH1A	4
KEGG	hsa00120	Primary bile acid biosynthesis	2/898	17/8144	0.5739	1	0.9435	SCP2/CYP7B1	2
KEGG	hsa00910	Nitrogen metabolism	2/898	17/8144	0.5739	1	0.9435	GLUD2/CA14	2
KEGG	hsa04970	Salivary secretion	10/898	93/8144	0.5834	1	0.9435	ADCY8/ADCY1/CALM1/ADRA1D/ITPR2/PRH1/ATP1B2/ADRA1A/ADRB2/GNAQ	10
KEGG	hsa05214	Glioma	8/898	75/8144	0.5949	1	0.9435	CALM1/CDK4/CAMK1D/SOS2/AKT3/MTOR/SOS1/RB1	8
KEGG	hsa05163	Human cytomegalovirus infection	24/898	225/8144	0.6018	1	0.9435	CCL3/ADCY8/BID/ADCY1/CTNNB1/CALM1/CDK4/HLA-C/SOS2/AKT3/MTOR/RHEB/IL6/PTGER3/SOS1/CASP3/GNB4/ITPR2/PPP3CA/GNB1/GNA11/RB1/HLA-G/GNAQ	24
KEGG	hsa00620	Pyruvate metabolism	5/898	47/8144	0.6032	1	0.9435	LDHC/ME1/MDH1/ADH1A/ALDH3A2	5
KEGG	hsa00061	Fatty acid biosynthesis	2/898	18/8144	0.6058	1	0.9435	ACSL6/ACSL1	2
KEGG	hsa04120	Ubiquitin mediated proteolysis	15/898	142/8144	0.6109	1	0.9435	PIAS2/HERC1/PIAS1/RHOBTB1/CUL1/DET1/HERC4/UBE2H/FBXW8/RCHY1/CUL3/UBE2E1/KLHL13/SOCS3/UBE2D2	15
KEGG	hsa04936	Alcoholic liver disease	15/898	142/8144	0.6109	1	0.9435	CPT1C/CTNNB1/PRKAB2/PRKAA2/ADIPOR1/AKT3/MAPK9/IL6/CASP3/SCD/NOX4/MAP2K4/ADH1A/FOXO1/ALDH3A2	15
KEGG	hsa05134	Legionellosis	6/898	57/8144	0.6112	1	0.9435	IL6/CASP3/HSPD1/TLR2/SEC22B/HSPA2	6
KEGG	hsa05330	Allograft rejection	4/898	38/8144	0.6162	1	0.9435	HLA-DRB5/HLA-C/HLA-DRB1/HLA-G	4
KEGG	hsa04145	Phagosome	16/898	152/8144	0.6178	1	0.9435	HLA-DRB5/FCGR2C/SEC61B/HLA-C/HLA-DRB1/TUBB2A/RAB5A/TUBB8/TUBB6/TLR2/SEC22B/DYNC1LI1/ITGA2/ITGB5/HLA-G/SEC61A2	16
KEGG	hsa00280	Valine, leucine and isoleucine degradation	5/898	48/8144	0.6224	1	0.9435	ABAT/OXCT2/HMGCLL1/IL4I1/ALDH3A2	5
KEGG	hsa05213	Endometrial cancer	6/898	58/8144	0.6285	1	0.9435	CTNNB1/SOS2/AKT3/CTNNA2/SOS1/PDPK1	6
KEGG	hsa04928	Parathyroid hormone synthesis, secretion and action	11/898	106/8144	0.6314	1	0.9435	SLC34A2/ADCY8/KL/ADCY1/MMP24/CYP24A1/ITPR2/PDE4C/GNA11/MEF2A/GNAQ	11
KEGG	hsa04260	Cardiac muscle contraction	9/898	87/8144	0.632	1	0.9435	SLC8A2/CACNG3/ACTC1/TNNI3/COX4I1/CACNG8/CACNA1F/ATP1B2/ASPH	9
KEGG	hsa04010	MAPK signaling pathway	31/898	294/8144	0.6344	1	0.9435	PAK2/CACNG3/ELK4/FGF8/KITLG/FGF9/FGF5/BDNF/FGF10/SOS2/AKT3/ERBB4/MAPK9/FGF4/SOS1/CASP3/FLNB/MAPK8IP2/RPS6KA5/MECOM/HSPA2/PPP3CA/PPM1A/MAPKAPK5/CACNG8/RAP1B/CACNA1F/MAP2K4/RRAS2/PTPRR/TGFB2	31
KEGG	hsa04392	Hippo signaling pathway - multiple species	3/898	29/8144	0.6347	1	0.9435	FAT4/DCHS2/RASSF6	3
KEGG	hsa04744	Phototransduction	3/898	29/8144	0.6347	1	0.9435	CALM1/GNB1/GUCY2D	3
KEGG	hsa01210	2-Oxocarboxylic acid metabolism	2/898	19/8144	0.6359	1	0.9435	NAGS/AADAT	2
KEGG	hsa03015	mRNA surveillance pathway	10/898	97/8144	0.6382	1	0.9435	CPSF7/MSI1/CPSF2/WDR33/PABPN1/RNGTT/PPP2R3C/DDX19A/PAPOLB/PPP2R1B	10
KEGG	hsa04070	Phosphatidylinositol signaling system	10/898	97/8144	0.6382	1	0.9435	DGKG/INPP5F/MTMR2/CALM1/MTMR14/MTMR3/ITPR2/PIP5K1B/SACM1L/DGKH	10
KEGG	hsa05215	Prostate cancer	10/898	97/8144	0.6382	1	0.9435	CTNNB1/EP300/SOS2/AKT3/MTOR/SOS1/PDPK1/RB1/CREBBP/FOXO1	10
KEGG	hsa00020	Citrate cycle (TCA cycle)	3/898	30/8144	0.6579	1	0.9435	OGDHL/SUCLA2/MDH1	3
KEGG	hsa05144	Malaria	5/898	50/8144	0.659	1	0.9435	GYPB/IL6/SELP/TLR2/TGFB2	5
KEGG	hsa00670	One carbon pool by folate	2/898	20/8144	0.6641	1	0.9435	MTHFD2L/TYMS	2
KEGG	hsa04917	Prolactin signaling pathway	7/898	70/8144	0.6652	1	0.9435	ESR2/SOS2/AKT3/MAPK9/SOS1/TNFRSF11A/SOCS3	7
KEGG	hsa03440	Homologous recombination	4/898	41/8144	0.6768	1	0.9435	RPA1/RAD54B/RPA2/NBN	4
KEGG	hsa00140	Steroid hormone biosynthesis	6/898	61/8144	0.6778	1	0.9435	HSD11B1L/CYP7B1/HSD17B12/CYP1B1/CYP3A5/SRD5A1	6
KEGG	hsa04530	Tight junction	17/898	169/8144	0.6939	1	0.9435	BVES/TJP1/CDK4/PRKAB2/GATA4/JAM2/PRKAA2/ARPC1A/MAPK9/ARHGAP17/CLDN5/MYH10/ACTN1/PARD6G/TIAM1/AMOT/PPP2R1B	17
KEGG	hsa04914	Progesterone-mediated oocyte maturation	10/898	102/8144	0.7008	1	0.9435	ADCY8/ADCY1/MOS/CDK1/MAD2L1/AKT3/PGR/MAPK9/CPEB1/MAD1L1	10
KEGG	hsa04972	Pancreatic secretion	10/898	102/8144	0.7008	1	0.9435	ADCY8/ADCY1/TRPC1/CPA2/PLA2G10/ITPR2/CCK/RAP1B/ATP1B2/GNAQ	10
KEGG	hsa05145	Toxoplasmosis	11/898	112/8144	0.7035	1	0.9435	HLA-DRB5/LAMC2/AKT3/MAPK9/HLA-DRB1/CASP3/TLR2/PDPK1/HSPA2/LAMA2/TGFB2	11
KEGG	hsa00562	Inositol phosphate metabolism	7/898	73/8144	0.7082	1	0.9435	MINPP1/INPP5F/MTMR2/MTMR14/MTMR3/PIP5K1B/SACM1L	7
KEGG	hsa01524	Platinum drug resistance	7/898	73/8144	0.7082	1	0.9435	BID/AKT3/ABCC2/CASP3/PDPK1/BIRC5/POLH	7
KEGG	hsa04115	p53 signaling pathway	7/898	73/8144	0.7082	1	0.9435	BID/SESN3/CDK1/CCNG1/CDK4/CASP3/RCHY1	7
KEGG	hsa05323	Rheumatoid arthritis	9/898	93/8144	0.7106	1	0.9435	HLA-DRB5/CCL3/HLA-DRB1/IL6/TLR2/CXCL5/IL11/TNFRSF11A/TGFB2	9
KEGG	hsa00130	Ubiquinone and other terpenoid-quinone biosynthesis	1/898	11/8144	0.7236	1	0.9435	COQ3	1
KEGG	hsa05170	Human immunodeficiency virus 1 infection	21/898	212/8144	0.7332	1	0.9435	PAK2/BID/CDK1/CALM1/AP1M2/HLA-C/AKT3/MTOR/MAPK9/CUL1/CASP3/TLR2/GNB4/ITPR2/PPP3CA/GNB1/GNA11/WEE2/PAK3/HLA-G/GNAQ	21
KEGG	hsa04921	Oxytocin signaling pathway	15/898	154/8144	0.734	1	0.9435	ADCY8/KCNJ3/ADCY1/CACNG3/CALM1/PRKAB2/PRKAA2/CAMK1D/KCNJ2/PPP1R12B/ITPR2/PPP3CA/CACNG8/CACNA1F/GNAQ	15
KEGG	hsa04918	Thyroid hormone synthesis	7/898	75/8144	0.7348	1	0.9435	GPX7/ADCY8/ADCY1/ITPR2/DUOX1/ATP1B2/GNAQ	7
KEGG	hsa05166	Human T-cell leukemia virus 1 infection	22/898	222/8144	0.7361	1	0.9435	HLA-DRB5/ADCY8/ADCY1/ELK4/SLC25A4/EP300/CDK4/TBPL2/HLA-C/MAD2L1/AKT3/MAPK9/HLA-DRB1/IL6/SMAD2/PPP3CA/RB1/MAP2K4/CREBBP/MAD1L1/TGFB2/HLA-G	22
KEGG	hsa05321	Inflammatory bowel disease	6/898	65/8144	0.7366	1	0.9435	HLA-DRB5/HLA-DRB1/IL6/TLR2/SMAD2/TGFB2	6
KEGG	hsa03060	Protein export	2/898	23/8144	0.7383	1	0.9435	SEC61B/SEC61A2	2
KEGG	hsa04014	Ras signaling pathway	23/898	232/8144	0.739	1	0.9435	PAK2/FGF8/KITLG/CALM1/FGF9/FGF5/BDNF/FGF10/SOS2/AKT3/MAPK9/RAB5A/FGF4/PLA2G10/SOS1/GNB4/REL/TIAM1/GNB1/RAP1B/GRIN2A/PAK3/RRAS2	23
KEGG	hsa03020	RNA polymerase	3/898	34/8144	0.7402	1	0.9435	POLR1D/POLR3C/POLR3F	3
KEGG	hsa04932	Non-alcoholic fatty liver disease	15/898	155/8144	0.743	1	0.9435	BID/PRKAB2/PRKAA2/ADIPOR1/IRS2/COX4I1/AKT3/MAPK9/NDUFS3/IL6/MLXIPL/CASP3/NDUFS7/BCL2L11/SOCS3	15
KEGG	hsa04742	Taste transduction	8/898	86/8144	0.746	1	0.9435	ADCY8/GRM1/GABRA5/GABRA4/P2RX2/HTR1E/TAS2R4/TAS2R5	8
KEGG	hsa05212	Pancreatic cancer	7/898	76/8144	0.7474	1	0.9435	CDK4/AKT3/MTOR/MAPK9/SMAD2/RB1/TGFB2	7
KEGG	hsa05220	Chronic myeloid leukemia	7/898	76/8144	0.7474	1	0.9435	CDK4/SOS2/AKT3/SOS1/MECOM/RB1/TGFB2	7
KEGG	hsa03050	Proteasome	4/898	46/8144	0.7622	1	0.9435	PSMD9/PSMA8/PSMB5/PSMA2	4
KEGG	hsa05221	Acute myeloid leukemia	6/898	67/8144	0.7629	1	0.9435	SOS2/AKT3/MTOR/PER2/SOS1/JUP	6
KEGG	hsa04721	Synaptic vesicle cycle	7/898	78/8144	0.7713	1	0.9435	SLC6A11/CPLX2/AP2M1/SLC17A8/SLC6A1/SLC6A4/DNM2	7
KEGG	hsa00760	Nicotinate and nicotinamide metabolism	3/898	36/8144	0.775	1	0.9435	NT5C1B/NT5C2/NUDT12	3
KEGG	hsa04664	Fc epsilon RI signaling pathway	6/898	68/8144	0.7754	1	0.9435	SOS2/AKT3/MAPK9/SOS1/PDPK1/MAP2K4	6
KEGG	hsa05418	Fluid shear stress and atherosclerosis	13/898	139/8144	0.7758	1	0.9435	SUMO1/CTNNB1/CALM1/PRKAA2/AKT3/MAPK9/MMP2/BMPR1B/ACVR2A/MAP2K4/GPC1/MEF2A/BMP4	13
KEGG	hsa04976	Bile secretion	8/898	89/8144	0.7796	1	0.9435	KCNN2/ADCY8/ADCY1/ABCB1/ABCC2/HMGCR/ATP1B2/SLCO1B3	8
KEGG	hsa01521	EGFR tyrosine kinase inhibitor resistance	7/898	79/8144	0.7827	1	0.9435	SOS2/AKT3/NRG1/MTOR/IL6/SOS1/BCL2L11	7
KEGG	hsa01250	Biosynthesis of nucleotide sugars	3/898	37/8144	0.7909	1	0.9435	GMPPB/NANP/HK1	3
KEGG	hsa04330	Notch signaling pathway	5/898	59/8144	0.7942	1	0.9435	DLL1/EP300/NOTCH2/NUMB/CREBBP	5
KEGG	hsa00790	Folate biosynthesis	2/898	26/8144	0.798	1	0.9435	MOCOS/GPHN	2
KEGG	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	6/898	70/8144	0.7988	1	0.9435	TJP1/JAM2/MAPK9/PTPRZ1/CASP3/MAP2K4	6
KEGG	hsa05161	Hepatitis B	15/898	162/8144	0.8006	1	0.9435	BID/EP300/SOS2/AKT3/MAPK9/IL6/SOS1/CASP3/TLR2/DDX3X/RB1/MAP2K4/CREBBP/TGFB2/BIRC5	15
KEGG	hsa05206	MicroRNAs in cancer	30/898	310/8144	0.8052	1	0.9435	WNT3/MIR133A1/EP300/CCNG1/ABCB1/IRS2/SOS2/GLS2/MTOR/DICER1/CDCA5/CYP24A1/MIR194-1/MIR215/FZD3/MIR324/SOS1/CASP3/NOTCH2/CYP1B1/MIR152/RPS6KA5/MIR199A1/MIR375/MIR449A/FOXP1/MIR331/BCL2L11/CREBBP/TGFB2	30
KEGG	hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	1/898	14/8144	0.8054	1	0.9435	CHST6	1
KEGG	hsa04714	Thermogenesis	22/898	232/8144	0.8056	1	0.9435	ADCY8/BMP8B/CPT1C/ADCY1/PRKAB2/ACTL6B/PRKAA2/SMARCE1/ADCY10/ACSL6/SOS2/COX4I1/MTOR/NDUFS3/SMARCC2/RHEB/SOS1/ACSL1/ARID1A/NDUFS7/SMARCC1/DPF3	22
KEGG	hsa04730	Long-term depression	5/898	60/8144	0.8062	1	0.9435	GRM1/ITPR2/GNA11/PPP2R1B/GNAQ	5
KEGG	hsa04978	Mineral absorption	5/898	60/8144	0.8062	1	0.9435	SLC34A2/SLC8A2/STEAP2/ATP1B2/STEAP1	5
KEGG	hsa00062	Fatty acid elongation	2/898	27/8144	0.8151	1	0.9435	ELOVL2/HSD17B12	2
KEGG	hsa04660	T cell receptor signaling pathway	9/898	104/8144	0.8242	1	0.9435	PAK2/CDK4/SOS2/AKT3/MAPK9/SOS1/PDPK1/PPP3CA/PAK3	9
KEGG	hsa00603	Glycosphingolipid biosynthesis - globo and isoglobo series	1/898	15/8144	0.8269	1	0.9435	FUT9	1
KEGG	hsa00730	Thiamine metabolism	1/898	15/8144	0.8269	1	0.9435	TPK1	1
KEGG	hsa05012	Parkinson disease	25/898	266/8144	0.8315	1	0.9435	DRD2/SLC25A4/SLC39A8/CALM1/PSMD9/COX4I1/MAPK9/TUBB2A/NDUFS3/PSMA8/TUBB8/CASP3/TUBB6/SNCAIP/ITPR2/PSMB5/ATF6/NDUFS7/KIF5C/MFN1/KLC3/GPR37/KIF5B/PSMA2/GNAL	25
KEGG	hsa03250	Viral life cycle - HIV-1	5/898	63/8144	0.8389	1	0.9435	CPSF7/EP300/FEZ1/SUPT5H/CREBBP	5
KEGG	hsa00591	Linoleic acid metabolism	2/898	29/8144	0.8453	1	0.9435	PLA2G10/ALOX15	2
KEGG	hsa00360	Phenylalanine metabolism	1/898	16/8144	0.8461	1	0.9435	IL4I1	1
KEGG	hsa04380	Osteoclast differentiation	11/898	128/8144	0.849	1	0.9435	FCGR2C/FHL2/AKT3/MAPK9/TNFRSF11B/PPP3CA/SIRPB1/TNFRSF11A/CALCR/SOCS3/TGFB2	11
KEGG	hsa05320	Autoimmune thyroid disease	4/898	53/8144	0.8509	1	0.9435	HLA-DRB5/HLA-C/HLA-DRB1/HLA-G	4
KEGG	hsa05162	Measles	12/898	139/8144	0.8533	1	0.9435	BID/CDK4/CSNK2A1/AKT3/MAPK9/RAB9B/IL6/CASP3/TLR2/HSPA2/RAB9A/RCHY1	12
KEGG	hsa05152	Tuberculosis	16/898	180/8144	0.8533	1	0.9435	HLA-DRB5/FCGR2C/BID/CALM1/EP300/AKT3/MAPK9/HLA-DRB1/RAB5A/IL6/CASP3/HSPD1/TLR2/PPP3CA/CREBBP/TGFB2	16
KEGG	hsa00053	Ascorbate and aldarate metabolism	2/898	30/8144	0.8587	1	0.9435	KL/ALDH3A2	2
KEGG	hsa00630	Glyoxylate and dicarboxylate metabolism	2/898	30/8144	0.8587	1	0.9435	MDH1/CAT	2
KEGG	hsa04722	Neurotrophin signaling pathway	10/898	119/8144	0.859	1	0.9435	CALM1/BDNF/SOS2/AKT3/MAPK9/SOS1/PDPK1/RPS6KA5/RAP1B/PRDM4	10
KEGG	hsa05164	Influenza A	15/898	171/8144	0.8603	1	0.9435	HLA-DRB5/BID/SLC25A4/EP300/CDK4/AKT3/HLA-DRB1/PABPN1/IL6/CASP3/DNAJB1/TRIM25/DNAJC3/CREBBP/SOCS3	15
KEGG	hsa00450	Selenocompound metabolism	1/898	17/8144	0.8631	1	0.9435	PAPSS2	1
KEGG	hsa04630	JAK-STAT signaling pathway	14/898	162/8144	0.8676	1	0.9435	PIAS2/IL20RA/PIAS1/EP300/SOS2/AKT3/MTOR/IL6/SOS1/IL22RA2/IL11/IL7/CREBBP/SOCS3	14
KEGG	hsa04975	Fat digestion and absorption	3/898	43/8144	0.8678	1	0.9435	ABCA1/PLA2G10/LIPF	3
KEGG	hsa04640	Hematopoietic cell lineage	8/898	99/8144	0.8678	1	0.9435	HLA-DRB5/KITLG/HLA-DRB1/IL6/IL11/ITGA2/IL7/GP1BB	8
KEGG	hsa05310	Asthma	2/898	31/8144	0.871	1	0.9435	HLA-DRB5/HLA-DRB1	2
KEGG	hsa04612	Antigen processing and presentation	6/898	78/8144	0.8739	1	0.9435	HLA-DRB5/KLRC3/HLA-C/HLA-DRB1/HSPA2/HLA-G	6
KEGG	hsa04142	Lysosome	11/898	132/8144	0.8749	1	0.9435	SUMF1/AP1M2/NPC2/SGSH/IGF2R/AP3M1/GNS/DMXL2/PSAP/IDUA/MFSD8	11
KEGG	hsa00010	Glycolysis / Gluconeogenesis	5/898	67/8144	0.8754	1	0.9435	LDHC/MINPP1/HK1/ADH1A/ALDH3A2	5
KEGG	hsa05417	Lipid and atherosclerosis	19/898	215/8144	0.877	1	0.9435	CCL3/BID/CALM1/MIB1/AKT3/MAPK9/ABCA1/POU2F3/IL6/CASP3/HSPD1/SELP/TLR2/PDPK1/HSPA2/PPP3CA/ATF6/RAP1B/MAP2K4	19
KEGG	hsa04962	Vasopressin-regulated water reabsorption	3/898	44/8144	0.8778	1	0.9435	RAB5A/AQP2/DYNC1LI1	3
KEGG	hsa04340	Hedgehog signaling pathway	4/898	56/8144	0.8793	1	0.9435	PTCH1/CUL1/EFCAB7/CUL3	4
KEGG	hsa03018	RNA degradation	6/898	79/8144	0.8813	1	0.9435	DCP1B/HSPD1/EXOSC9/PARN/LSM2/NUDT16	6
KEGG	hsa04668	TNF signaling pathway	9/898	112/8144	0.8827	1	0.9435	AKT3/MAPK9/DNM1L/IL6/CASP3/CXCL5/RPS6KA5/MAP2K4/SOCS3	9
KEGG	hsa05130	Pathogenic Escherichia coli infection	17/898	197/8144	0.8884	1	0.9435	BAIAP2L1/PAK2/MYO5C/TJP1/ARPC1A/MAPK9/TUBB2A/MYO1D/IL6/TUBB8/CASP3/TUBB6/MYO5A/CLDN5/MYH10/PAK3/MYO6	17
KEGG	hsa04611	Platelet activation	10/898	124/8144	0.8901	1	0.9435	ADCY8/ADCY1/AKT3/COL1A2/ITPR2/RAP1B/ITGA2/GP1BB/COL3A1/GNAQ	10
KEGG	hsa05031	Amphetamine addiction	5/898	69/8144	0.8908	1	0.9435	CALM1/ARC/PPP3CA/GRIN2A/GRIA4	5
KEGG	hsa00051	Fructose and mannose metabolism	2/898	33/8144	0.8928	1	0.9435	GMPPB/HK1	2
KEGG	hsa04130	SNARE interactions in vesicular transport	2/898	33/8144	0.8928	1	0.9435	SEC22B/VAMP4	2
KEGG	hsa05230	Central carbon metabolism in cancer	5/898	70/8144	0.8979	1	0.9435	LDHC/AKT3/GLS2/MTOR/HK1	5
KEGG	hsa04144	Endocytosis	22/898	251/8144	0.9001	1	0.9435	ARPC1A/HLA-C/ZFYVE16/CHMP5/RAB5A/ACAP2/GBF1/AP2M1/IGF2R/SMAD2/PSD/PARD6G/HSPA2/PIP5K1B/CHMP2B/LDLRAP1/KIF5C/ZFYVE9/KIF5B/DNM2/SNX2/HLA-G	22
KEGG	hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	1/898	20/8144	0.9036	1	0.9435	CHSY3	1
KEGG	hsa04973	Carbohydrate digestion and absorption	3/898	47/8144	0.9041	1	0.9435	AKT3/HK1/ATP1B2	3
KEGG	hsa05020	Prion disease	24/898	273/8144	0.9061	1	0.9435	NCAM1/SLC25A4/CSNK2A1/PSMD9/COX4I1/MAPK9/TUBB2A/NDUFS3/PSMA8/IL6/TUBB8/CASP3/TUBB6/ITPR2/HSPA2/PPP3CA/PSMB5/NDUFS7/CACNA1F/GRIN2A/KIF5C/KLC3/KIF5B/PSMA2	24
KEGG	hsa00590	Arachidonic acid metabolism	4/898	61/8144	0.9163	1	0.9435	GPX7/PLA2G10/ALOX15/EPHX2	4
KEGG	hsa00520	Amino sugar and nucleotide sugar metabolism	3/898	49/8144	0.9186	1	0.9435	GMPPB/NANP/HK1	3
KEGG	hsa00565	Ether lipid metabolism	3/898	49/8144	0.9186	1	0.9435	UGT8/PLA2G10/AGPS	3
KEGG	hsa04672	Intestinal immune network for IgA production	3/898	49/8144	0.9186	1	0.9435	HLA-DRB5/HLA-DRB1/IL6	3
KEGG	hsa05030	Cocaine addiction	3/898	49/8144	0.9186	1	0.9435	DRD2/BDNF/GRIN2A	3
KEGG	hsa00500	Starch and sucrose metabolism	2/898	36/8144	0.919	1	0.9435	HK1/GBE1	2
KEGG	hsa00340	Histidine metabolism	1/898	22/8144	0.9238	1	0.9435	ALDH3A2	1
KEGG	hsa04650	Natural killer cell mediated cytotoxicity	10/898	131/8144	0.924	1	0.9435	KLRC3/BID/HLA-C/SOS2/MICA/SOS1/CASP3/PPP3CA/NCR2/HLA-G	10
KEGG	hsa04066	HIF-1 signaling pathway	8/898	109/8144	0.9249	1	0.9435	LDHC/EP300/AKT3/MTOR/IL6/EGLN3/HK1/CREBBP	8
KEGG	hsa05110	Vibrio cholerae infection	3/898	50/8144	0.9251	1	0.9435	TJP1/SEC61B/SEC61A2	3
KEGG	hsa00564	Glycerophospholipid metabolism	7/898	98/8144	0.9263	1	0.9435	DGKG/PLA2G10/GPAM/LPCAT3/CHAT/DGKH/GPAT2	7
KEGG	hsa04750	Inflammatory mediator regulation of TRP channels	7/898	98/8144	0.9263	1	0.9435	ADCY8/ADCY1/CALM1/HTR2C/MAPK9/ITPR2/GNAQ	7
KEGG	hsa04960	Aldosterone-regulated sodium reabsorption	2/898	37/8144	0.9264	1	0.9435	PDPK1/ATP1B2	2
KEGG	hsa05143	African trypanosomiasis	2/898	37/8144	0.9264	1	0.9435	IL6/GNAQ	2
KEGG	hsa04623	Cytosolic DNA-sensing pathway	4/898	63/8144	0.928	1	0.9435	POLR1D/IL6/POLR3C/POLR3F	4
KEGG	hsa00330	Arginine and proline metabolism	3/898	51/8144	0.9311	1	0.9435	P4HA3/CKB/ALDH3A2	3
KEGG	hsa04913	Ovarian steroidogenesis	3/898	51/8144	0.9311	1	0.9435	ADCY8/ADCY1/CYP1B1	3
KEGG	hsa05133	Pertussis	5/898	76/8144	0.9326	1	0.9435	CALM1/MAPK9/IL6/CASP3/CXCL5	5
KEGG	hsa05100	Bacterial invasion of epithelial cells	5/898	77/8144	0.9372	1	0.9435	CTNNB1/ARPC1A/CTNNA2/DNM2/FN1	5
KEGG	hsa05140	Leishmaniasis	5/898	77/8144	0.9372	1	0.9435	HLA-DRB5/FCGR2C/HLA-DRB1/TLR2/TGFB2	5
KEGG	hsa05160	Hepatitis C	12/898	157/8144	0.9388	1	0.9435	BID/CTNNB1/PIAS1/CDK4/SOS2/AKT3/SOS1/CASP3/CLDN5/RB1/SOCS3/PPP2R1B	12
KEGG	hsa00980	Metabolism of xenobiotics by cytochrome P450	5/898	78/8144	0.9415	1	0.9435	AKR7A2/HSD11B1L/CYP1B1/CYP3A5/ADH1A	5
KEGG	hsa00600	Sphingolipid metabolism	3/898	53/8144	0.9418	1	0.9435	B4GALNT1/UGT8/PSAP	3
KEGG	hsa00970	Aminoacyl-tRNA biosynthesis	4/898	66/8144	0.9428	1	0.9435	QRSL1/RARS2/DARS2/WARS2	4
KEGG	hsa04670	Leukocyte transendothelial migration	8/898	114/8144	0.9444	1	0.9435	CTNNB1/JAM2/CTNNA2/MMP2/THY1/CLDN5/ACTN1/RAP1B	8
KEGG	hsa05135	Yersinia infection	10/898	137/8144	0.9455	1	0.9435	ARHGEF7/ARPC1A/AKT3/MAPK9/IL6/PIP5K1B/MAP2K4/FN1/PKN2/GNAQ	10
KEGG	hsa00592	alpha-Linolenic acid metabolism	1/898	25/8144	0.9464	1	0.9435	PLA2G10	1
KEGG	hsa04658	Th1 and Th2 cell differentiation	6/898	92/8144	0.9491	1	0.9435	HLA-DRB5/DLL1/MAPK9/HLA-DRB1/NOTCH2/PPP3CA	6
KEGG	hsa04625	C-type lectin receptor signaling pathway	7/898	104/8144	0.9497	1	0.9435	CALM1/AKT3/MAPK9/IL6/ITPR2/PPP3CA/RRAS2	7
KEGG	hsa00830	Retinol metabolism	4/898	68/8144	0.9511	1	0.9435	ALDH1A3/CYP26A1/CYP3A5/ADH1A	4
KEGG	hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	1/898	27/8144	0.9576	1	0.9435	FUT9	1
KEGG	hsa04622	RIG-I-like receptor signaling pathway	4/898	70/8144	0.9582	1	0.9435	MAPK9/TRIM25/DDX3X/DHX58	4
KEGG	hsa01240	Biosynthesis of cofactors	11/898	153/8144	0.9584	1	0.9435	CMPK2/MTHFD2L/COQ3/CMPK1/CTPS2/GCLC/LIAS/GMPPB/TPK1/GPHN/ALDH3A2	11
KEGG	hsa04659	Th17 cell differentiation	7/898	108/8144	0.9614	1	0.9435	HLA-DRB5/MTOR/MAPK9/HLA-DRB1/IL6/SMAD2/PPP3CA	7
KEGG	hsa03008	Ribosome biogenesis in eukaryotes	7/898	109/8144	0.9639	1	0.9435	CSNK2A1/HEATR1/NMD3/WDR43/RPP38/NOB1/POP1	7
KEGG	hsa04610	Complement and coagulation cascades	5/898	85/8144	0.9651	1	0.9435	F13A1/PROC/F3/CFHR4/F7	5
KEGG	hsa04062	Chemokine signaling pathway	14/898	192/8144	0.9691	1	0.9435	CCL3/ADCY8/CXCL16/ADCY1/SOS2/AKT3/SOS1/CXCL14/GNB4/CXCL5/TIAM1/GNB1/RAP1B/GNAQ	14
KEGG	hsa04210	Apoptosis	9/898	136/8144	0.9709	1	0.9435	BID/AKT3/MAPK9/PTPN13/CASP3/PDPK1/ITPR2/BCL2L11/BIRC5	9
KEGG	hsa00052	Galactose metabolism	1/898	31/8144	0.9735	1	0.9435	HK1	1
KEGG	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	5/898	89/8144	0.9742	1	0.9435	CSNK2A1/AKT3/MTOR/TLR2/PPP3CA	5
KEGG	hsa04060	Cytokine-cytokine receptor interaction	23/898	295/8144	0.9756	1	0.9435	CCL3/CXCL16/BMP8B/IL20RA/AMH/BMP7/TNFRSF11B/ACVR1B/NODAL/IL6/BMPR1B/CXCL14/CXCL5/IL17RB/ACVR2A/IL11/BMP10/IL7/TNFRSF11A/BMP2/TGFB2/BMP4/GDF1	23
KEGG	hsa01200	Carbon metabolism	7/898	115/8144	0.976	1	0.9435	OGDHL/GLUD2/ME1/SUCLA2/MDH1/HK1/CAT	7
KEGG	hsa04620	Toll-like receptor signaling pathway	6/898	104/8144	0.9783	1	0.9435	CCL3/AKT3/MAPK9/IL6/TLR2/MAP2K4	6
KEGG	hsa03410	Base excision repair	1/898	33/8144	0.979	1	0.9435	POLE2	1
KEGG	hsa05208	Chemical carcinogenesis - reactive oxygen species	16/898	223/8144	0.9806	1	0.9435	PRKD1/SLC25A4/SOS2/COX4I1/AKT3/MAPK9/NDUFS3/SLC26A2/SOS1/CYP1B1/EPHX2/PDPK1/NDUFS7/NOX4/MAP2K4/CAT	16
KEGG	hsa00040	Pentose and glucuronate interconversions	1/898	34/8144	0.9813	1	0.9435	KL	1
KEGG	hsa04071	Sphingolipid signaling pathway	7/898	119/8144	0.9819	1	0.9435	BID/AKT3/MAPK9/PDPK1/PPP2R3C/PPP2R1B/GNAQ	7
KEGG	hsa05169	Epstein-Barr virus infection	14/898	202/8144	0.9822	1	0.9435	HLA-DRB5/BID/CDK4/HLA-C/AKT3/MAPK9/HLA-DRB1/IL6/CASP3/TLR2/RB1/MAP2K4/BCL2L11/HLA-G	14
KEGG	hsa04657	IL-17 signaling pathway	5/898	94/8144	0.9825	1	0.9435	MAPK9/IL6/CASP3/CXCL5/IL17RB	5
KEGG	hsa05415	Diabetic cardiomyopathy	14/898	203/8144	0.9832	1	0.9435	SLC25A4/TNNI3/COX4I1/AKT3/MTOR/MAPK9/NDUFS3/MMP2/SMAD2/COL1A2/NDUFS7/AGTR1/COL3A1/TGFB2	14
KEGG	hsa05203	Viral carcinogenesis	14/898	204/8144	0.9841	1	0.9435	CDK1/EP300/CDK4/TBPL2/HLA-C/CASP3/REL/ACTN1/DDX3X/RB1/CREBBP/HDAC6/MAD1L1/HLA-G	14
KEGG	hsa04662	B cell receptor signaling pathway	4/898	82/8144	0.9844	1	0.9435	SOS2/AKT3/SOS1/PPP3CA	4
KEGG	hsa05150	Staphylococcus aureus infection	5/898	96/8144	0.9851	1	0.9435	HLA-DRB5/FCGR2C/HLA-DRB1/KRT19/SELP	5
KEGG	hsa03040	Spliceosome	9/898	147/8144	0.9857	1	0.9435	SNRNP40/PRPF31/SNRNP27/PRPF3/SNRPC/HSPA2/DDX46/LSM2/PPIH	9
KEGG	hsa05204	Chemical carcinogenesis - DNA adducts	3/898	69/8144	0.9859	1	0.9435	HSD11B1L/CYP1B1/CYP3A5	3
KEGG	hsa05216	Thyroid cancer	1/898	37/8144	0.9869	1	0.9435	CTNNB1	1
KEGG	hsa04061	Viral protein interaction with cytokine and cytokine receptor	5/898	100/8144	0.9892	1	0.9435	CCL3/IL20RA/IL6/CXCL14/CXCL5	5
KEGG	hsa00260	Glycine, serine and threonine metabolism	1/898	40/8144	0.9908	1	0.9435	BHMT	1
KEGG	hsa00480	Glutathione metabolism	2/898	58/8144	0.9908	1	0.9435	GPX7/GCLC	2
KEGG	hsa04370	VEGF signaling pathway	2/898	59/8144	0.9917	1	0.9435	AKT3/PPP3CA	2
KEGG	hsa04217	Necroptosis	9/898	159/8144	0.9937	1	0.9435	BID/GLUD2/SLC25A4/MAPK9/CHMP5/DNM1L/ALOX15/CHMP2B/FAF1	9
KEGG	hsa00983	Drug metabolism - other enzymes	3/898	80/8144	0.995	1	0.9435	CMPK1/DPYS/ITPA	3
KEGG	hsa04666	Fc gamma R-mediated phagocytosis	4/898	97/8144	0.9958	1	0.9435	ARPC1A/AKT3/PIP5K1B/DNM2	4
KEGG	hsa05202	Transcriptional misregulation in cancer	11/898	193/8144	0.9967	1	0.9435	ELK4/BMP2K/PAX5/PER2/PAX7/IL6/WT1/JUP/REL/NCOR1/FOXO1	11
KEGG	hsa03010	Ribosome	8/898	158/8144	0.9974	1	0.9435	RPL24/RPL31/MRPL30/RPL9/MRPL9/MRPL17/MRPS6/RPL36	8
KEGG	hsa04621	NOD-like receptor signaling pathway	10/898	184/8144	0.9974	1	0.9435	DHX33/MAPK9/DNM1L/IL6/GABARAPL1/ITPR2/ANTXR2/MFN1/GPRC6A/PKN2	10
KEGG	hsa04064	NF-kappa B signaling pathway	4/898	104/8144	0.9978	1	0.9435	CSNK2A1/CARD10/TRIM25/TNFRSF11A	4
KEGG	hsa00982	Drug metabolism - cytochrome P450	2/898	72/8144	0.9979	1	0.9435	CYP3A5/ADH1A	2
KEGG	hsa05034	Alcoholism	10/898	187/8144	0.9979	1	0.9435	DRD2/CALM1/BDNF/SOS2/SOS1/GNB4/GNB1/GRIN2A/HDAC6/NPY	10
KEGG	hsa05131	Shigellosis	14/898	247/8144	0.9989	1	0.9435	UBE2V2/ARPC1A/AKT3/MTOR/MAPK9/CUL1/PFN3/RPS6KA5/ITPR2/ACTN1/HK1/RRAGC/FOXO1/UBE2D2	14
KEGG	hsa04613	Neutrophil extracellular trap formation	9/898	190/8144	0.9994	1	0.9435	SLC25A4/AKT3/MTOR/CLCN3/SELP/TLR2/HDAC6/CLCN4/CLCN5	9
KEGG	hsa05322	Systemic lupus erythematosus	5/898	136/8144	0.9995	1	0.9435	HLA-DRB5/HLA-DRB1/ACTN1/GRIN2A/SSB	5
KEGG	hsa01230	Biosynthesis of amino acids	1/898	75/8144	0.9999	1	0.9435	NAGS	1
KEGG	hsa05171	Coronavirus disease - COVID-19	10/898	232/8144	0.9999	1	0.9435	F13A1/RPL24/RPL31/MAPK9/IL6/SELP/TLR2/RPL9/AGTR1/RPL36	10
KEGG	hsa04740	Olfactory transduction	25/898	440/8144	1	1	0.9435	OR13G1/OR5H2/SLC8A2/CALM1/OR5K1/OR2AG2/OR4K15/OR4C45/OR2T8/OR8D1/OR5K2/OR4D2/GNB1/OR2M2/OR5M1/OR6C68/OR10G7/OR5K4/OR6C75/OR1J1/OR4C15/OR5K3/GNAL/OR7G1/GUCY2D	25
KEGG	hsa00190	Oxidative phosphorylation	3/898	134/8144	1	1	0.9435	COX4I1/NDUFS3/NDUFS7	3