ONTOLOGY ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count BP GO:1903900 regulation of viral life cycle 6/83 149/18670 5.317e-05 0.04062 0.04062 CCL8/IFIT1/APOBEC3A/IFI27/FCN1/HACD3 6 BP GO:0045069 regulation of viral genome replication 5/83 95/18670 6.51e-05 0.04062 0.04062 CCL8/IFIT1/APOBEC3A/IFI27/HACD3 5 BP GO:0019079 viral genome replication 5/83 122/18670 0.0002121 0.08823 0.08823 CCL8/IFIT1/APOBEC3A/IFI27/HACD3 5 BP GO:0050792 regulation of viral process 6/83 208/18670 0.0003291 0.1027 0.1027 CCL8/IFIT1/APOBEC3A/IFI27/FCN1/HACD3 6 BP GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism 6/83 222/18670 0.0004653 0.1032 0.1032 CCL8/IFIT1/APOBEC3A/IFI27/FCN1/HACD3 6 BP GO:1903901 negative regulation of viral life cycle 4/83 85/18670 0.0005592 0.1032 0.1032 CCL8/IFIT1/APOBEC3A/FCN1 4 BP GO:0009615 response to virus 7/83 326/18670 0.000619 0.1032 0.1032 CCL8/IFI44L/IFIT1/IFNE/APOBEC3A/IFI27/IFIT3 7 BP GO:0051607 defense response to virus 6/83 238/18670 0.0006708 0.1032 0.1032 IFI44L/IFIT1/IFNE/APOBEC3A/IFI27/IFIT3 6 BP GO:0060337 type I interferon signaling pathway 4/83 95/18670 0.0008502 0.1032 0.1032 IFIT1/ZBP1/IFI27/IFIT3 4 BP GO:0071357 cellular response to type I interferon 4/83 95/18670 0.0008502 0.1032 0.1032 IFIT1/ZBP1/IFI27/IFIT3 4 BP GO:0034340 response to type I interferon 4/83 99/18670 0.0009919 0.1032 0.1032 IFIT1/ZBP1/IFI27/IFIT3 4 BP GO:0048525 negative regulation of viral process 4/83 99/18670 0.0009919 0.1032 0.1032 CCL8/IFIT1/APOBEC3A/FCN1 4 BP GO:0044827 modulation by host of viral genome replication 2/83 16/18670 0.00225 0.2052 0.2052 CCL8/IFI27 2 BP GO:0045071 negative regulation of viral genome replication 3/83 59/18670 0.002302 0.2052 0.2052 CCL8/IFIT1/APOBEC3A 3 BP GO:0019058 viral life cycle 6/83 328/18670 0.003412 0.2838 0.2838 CCL8/IFIT1/APOBEC3A/IFI27/FCN1/HACD3 6 MF GO:0031406 carboxylic acid binding 4/69 193/17697 0.006827 0.2715 0.2493 LYVE1/PCK1/FCN1/RXRA 4 MF GO:0019239 deaminase activity 2/69 32/17697 0.006891 0.2715 0.2493 ZBP1/APOBEC3A 2 MF GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 2/69 34/17697 0.007755 0.2715 0.2493 ZBP1/APOBEC3A 2 MF GO:0016831 carboxy-lyase activity 2/69 35/17697 0.008204 0.2715 0.2493 PDXDC1/PCK1 2 MF GO:0043177 organic acid binding 4/69 205/17697 0.008409 0.2715 0.2493 LYVE1/PCK1/FCN1/RXRA 4 MF GO:0000287 magnesium ion binding 4/69 213/17697 0.009587 0.2715 0.2493 TDP2/TREX2/FARSB/PCK1 4 MF GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 3/69 123/17697 0.0123 0.2715 0.2493 ZBP1/APOBEC3A/VNN1 3 MF GO:0016830 carbon-carbon lyase activity 2/69 51/17697 0.01689 0.2715 0.2493 PDXDC1/PCK1 2 MF GO:0001085 RNA polymerase II transcription factor binding 3/69 155/17697 0.02267 0.2715 0.2493 IFI27/ATN1/GTF2E1 3 MF GO:0030145 manganese ion binding 2/69 62/17697 0.02438 0.2715 0.2493 TDP2/PCK1 2 MF GO:0016829 lyase activity 3/69 187/17697 0.03659 0.2715 0.2493 PDXDC1/PCK1/HACD3 3 MF GO:0016832 aldehyde-lyase activity 1/69 11/17697 0.04207 0.2715 0.2493 PDXDC1 1 MF GO:0102991 myristoyl-CoA hydrolase activity 1/69 11/17697 0.04207 0.2715 0.2493 ACOT2 1 MF GO:1901612 cardiolipin binding 1/69 11/17697 0.04207 0.2715 0.2493 UQCC3 1 MF GO:0004000 adenosine deaminase activity 1/69 12/17697 0.04581 0.2715 0.2493 ZBP1 1 MF GO:0004126 cytidine deaminase activity 1/69 12/17697 0.04581 0.2715 0.2493 APOBEC3A 1 MF GO:0016004 phospholipase activator activity 1/69 12/17697 0.04581 0.2715 0.2493 CCL8 1 MF GO:0033691 sialic acid binding 1/69 12/17697 0.04581 0.2715 0.2493 FCN1 1 MF GO:0061578 Lys63-specific deubiquitinase activity 1/69 12/17697 0.04581 0.2715 0.2493 DESI2 1 MF GO:0019207 kinase regulator activity 3/69 207/17697 0.04709 0.2715 0.2493 PIK3R5/RGCC/ITPRIP 3 MF GO:0008296 3'-5'-exodeoxyribonuclease activity 1/69 13/17697 0.04953 0.2715 0.2493 TREX2 1 MF GO:0016251 RNA polymerase II general transcription initiation factor activity 1/69 13/17697 0.04953 0.2715 0.2493 GTF2E1 1 MF GO:0016423 tRNA (guanine) methyltransferase activity 1/69 13/17697 0.04953 0.2715 0.2493 METTL1 1 MF GO:0016290 palmitoyl-CoA hydrolase activity 1/69 14/17697 0.05324 0.2715 0.2493 ACOT2 1 MF GO:0046935 1-phosphatidylinositol-3-kinase regulator activity 1/69 14/17697 0.05324 0.2715 0.2493 PIK3R5 1 MF GO:0060229 lipase activator activity 1/69 14/17697 0.05324 0.2715 0.2493 CCL8 1 MF GO:0042809 vitamin D receptor binding 1/69 15/17697 0.05694 0.2715 0.2493 RXRA 1 MF GO:1901611 phosphatidylglycerol binding 1/69 15/17697 0.05694 0.2715 0.2493 UQCC3 1 MF GO:1990380 Lys48-specific deubiquitinase activity 1/69 15/17697 0.05694 0.2715 0.2493 DESI2 1 MF GO:0005525 GTP binding 4/69 374/17697 0.05816 0.2715 0.2493 IFI44L/PCK1/SAR1B/ARL14 4 MF GO:0032550 purine ribonucleoside binding 4/69 378/17697 0.06001 0.2715 0.2493 IFI44L/PCK1/SAR1B/ARL14 4 MF GO:0004697 protein kinase C activity 1/69 16/17697 0.06062 0.2715 0.2493 PKN3 1 MF GO:0005521 lamin binding 1/69 16/17697 0.06062 0.2715 0.2493 IFI27 1 MF GO:0052742 phosphatidylinositol kinase activity 1/69 16/17697 0.06062 0.2715 0.2493 PI4KB 1 MF GO:0001883 purine nucleoside binding 4/69 381/17697 0.06143 0.2715 0.2493 IFI44L/PCK1/SAR1B/ARL14 4 MF GO:0032549 ribonucleoside binding 4/69 382/17697 0.0619 0.2715 0.2493 IFI44L/PCK1/SAR1B/ARL14 4 MF GO:0005132 type I interferon receptor binding 1/69 17/17697 0.06428 0.2715 0.2493 IFNE 1 MF GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/69 17/17697 0.06428 0.2715 0.2493 PIK3R5 1 MF GO:0001882 nucleoside binding 4/69 389/17697 0.06527 0.2715 0.2493 IFI44L/PCK1/SAR1B/ARL14 4 MF GO:0019001 guanyl nucleotide binding 4/69 394/17697 0.06774 0.2715 0.2493 IFI44L/PCK1/SAR1B/ARL14 4 MF GO:0032561 guanyl ribonucleotide binding 4/69 394/17697 0.06774 0.2715 0.2493 IFI44L/PCK1/SAR1B/ARL14 4 MF GO:0001972 retinoic acid binding 1/69 19/17697 0.07157 0.2715 0.2493 RXRA 1 MF GO:0070300 phosphatidic acid binding 1/69 19/17697 0.07157 0.2715 0.2493 UQCC3 1 MF GO:0140223 general transcription initiation factor activity 1/69 19/17697 0.07157 0.2715 0.2493 GTF2E1 1 MF GO:0001091 RNA polymerase II basal transcription factor binding 1/69 20/17697 0.0752 0.2715 0.2493 GTF2E1 1 MF GO:0008329 signaling pattern recognition receptor activity 1/69 20/17697 0.0752 0.2715 0.2493 FCN1 1 MF GO:0016922 nuclear receptor binding 1/69 20/17697 0.0752 0.2715 0.2493 RXRA 1 MF GO:0031683 G-protein beta/gamma-subunit complex binding 1/69 20/17697 0.0752 0.2715 0.2493 PIK3R5 1 MF GO:0047617 acyl-CoA hydrolase activity 1/69 20/17697 0.0752 0.2715 0.2493 ACOT2 1 MF GO:0005540 hyaluronic acid binding 1/69 21/17697 0.07881 0.2715 0.2493 LYVE1 1 MF GO:0017049 GTP-Rho binding 1/69 21/17697 0.07881 0.2715 0.2493 PKN3 1 MF GO:0038187 pattern recognition receptor activity 1/69 21/17697 0.07881 0.2715 0.2493 FCN1 1 MF GO:0140101 catalytic activity, acting on a tRNA 2/69 122/17697 0.08207 0.2715 0.2493 FARSB/METTL1 2 MF GO:0016289 CoA hydrolase activity 1/69 22/17697 0.0824 0.2715 0.2493 ACOT2 1 MF GO:0004984 olfactory receptor activity 4/69 427/17697 0.08523 0.2715 0.2493 OR52N4/OR5H1/OR2A5/OR4A5 4 MF GO:0016895 exodeoxyribonuclease activity, producing 5'-phosphomonoesters 1/69 23/17697 0.08598 0.2715 0.2493 TREX2 1 MF GO:0070412 R-SMAD binding 1/69 23/17697 0.08598 0.2715 0.2493 RGCC 1 MF GO:0004529 exodeoxyribonuclease activity 1/69 25/17697 0.09311 0.2841 0.2608 TREX2 1 MF GO:0015101 organic cation transmembrane transporter activity 1/69 25/17697 0.09311 0.2841 0.2608 SLC7A8 1 MF GO:0001664 G protein-coupled receptor binding 3/69 280/17697 0.0961 0.2883 0.2647 CCL8/UTS2B/FCN1 3 MF GO:0052689 carboxylic ester hydrolase activity 2/69 136/17697 0.09865 0.2911 0.2673 ABHD16A/ACOT2 2 MF GO:0071889 14-3-3 protein binding 1/69 29/17697 0.1072 0.3112 0.2857 PI4KB 1 MF GO:0016874 ligase activity 2/69 145/17697 0.1098 0.3113 0.2858 FARSB/DPH6 2 MF GO:0008528 G protein-coupled peptide receptor activity 2/69 146/17697 0.111 0.3113 0.2858 RXFP1/GP1BA 2 MF GO:0015175 neutral amino acid transmembrane transporter activity 1/69 31/17697 0.1141 0.3113 0.2858 SLC7A8 1 MF GO:0042605 peptide antigen binding 1/69 31/17697 0.1141 0.3113 0.2858 SLC7A8 1 MF GO:0001653 peptide receptor activity 2/69 152/17697 0.1186 0.3128 0.2872 RXFP1/GP1BA 2 MF GO:0005342 organic acid transmembrane transporter activity 2/69 153/17697 0.1199 0.3128 0.2872 SLC7A8/MPC1 2 MF GO:0046943 carboxylic acid transmembrane transporter activity 2/69 153/17697 0.1199 0.3128 0.2872 SLC7A8/MPC1 2 MF GO:0008175 tRNA methyltransferase activity 1/69 34/17697 0.1245 0.3201 0.2939 METTL1 1 MF GO:0005501 retinoid binding 1/69 35/17697 0.1279 0.3206 0.2944 RXRA 1 MF GO:0003713 transcription coactivator activity 3/69 319/17697 0.1283 0.3206 0.2944 NUPR1/ING4/RXRA 3 MF GO:0019840 isoprenoid binding 1/69 36/17697 0.1313 0.3238 0.2973 RXRA 1 MF GO:0016790 thiolester hydrolase activity 1/69 37/17697 0.1347 0.3277 0.3008 ACOT2 1 MF GO:0004812 aminoacyl-tRNA ligase activity 1/69 41/17697 0.1482 0.3509 0.3222 FARSB 1 MF GO:0016875 ligase activity, forming carbon-oxygen bonds 1/69 41/17697 0.1482 0.3509 0.3222 FARSB 1 MF GO:0015932 nucleobase-containing compound transmembrane transporter activity 1/69 43/17697 0.1548 0.3513 0.3226 SLC29A3 1 MF GO:0048020 CCR chemokine receptor binding 1/69 43/17697 0.1548 0.3513 0.3226 CCL8 1 MF GO:0019887 protein kinase regulator activity 2/69 180/17697 0.1557 0.3513 0.3226 RGCC/ITPRIP 2 MF GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/69 44/17697 0.1581 0.3513 0.3226 DPH6 1 MF GO:1901505 carbohydrate derivative transmembrane transporter activity 1/69 44/17697 0.1581 0.3513 0.3226 SLC29A3 1 MF GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/69 45/17697 0.1614 0.3543 0.3253 SSH1 1 MF GO:0004879 nuclear receptor activity 1/69 47/17697 0.1679 0.3599 0.3304 RXRA 1 MF GO:0098531 transcription factor activity, direct ligand regulated sequence-specific DNA binding 1/69 47/17697 0.1679 0.3599 0.3304 RXRA 1 MF GO:0008009 chemokine activity 1/69 49/17697 0.1744 0.3667 0.3367 CCL8 1 MF GO:0008028 monocarboxylic acid transmembrane transporter activity 1/69 50/17697 0.1777 0.3667 0.3367 MPC1 1 MF GO:0000993 RNA polymerase II complex binding 1/69 53/17697 0.1873 0.3667 0.3367 GTF2E1 1 MF GO:0001102 RNA polymerase II activating transcription factor binding 1/69 53/17697 0.1873 0.3667 0.3367 IFI27 1 MF GO:0004518 nuclease activity 2/69 205/17697 0.1904 0.3667 0.3367 TDP2/TREX2 2 MF GO:0015179 L-amino acid transmembrane transporter activity 1/69 54/17697 0.1904 0.3667 0.3367 SLC7A8 1 MF GO:0030170 pyridoxal phosphate binding 1/69 54/17697 0.1904 0.3667 0.3367 PDXDC1 1 MF GO:0070279 vitamin B6 binding 1/69 54/17697 0.1904 0.3667 0.3367 PDXDC1 1 MF GO:0140098 catalytic activity, acting on RNA 3/69 386/17697 0.1908 0.3667 0.3367 TDP2/FARSB/METTL1 3 MF GO:0008408 3'-5' exonuclease activity 1/69 55/17697 0.1936 0.3667 0.3367 TREX2 1 MF GO:0003707 steroid hormone receptor activity 1/69 56/17697 0.1968 0.3667 0.3367 RXRA 1 MF GO:0016836 hydro-lyase activity 1/69 56/17697 0.1968 0.3667 0.3367 HACD3 1 MF GO:0008514 organic anion transmembrane transporter activity 2/69 211/17697 0.1989 0.3667 0.3367 SLC7A8/MPC1 2 MF GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/69 57/17697 0.1999 0.3667 0.3367 TREX2 1 MF GO:0140097 catalytic activity, acting on DNA 2/69 213/17697 0.2017 0.3667 0.3367 TDP2/TREX2 2 MF GO:0004536 deoxyribonuclease activity 1/69 59/17697 0.2062 0.3674 0.3373 TREX2 1 MF GO:0005507 copper ion binding 1/69 59/17697 0.2062 0.3674 0.3373 S100A5 1 MF GO:0000049 tRNA binding 1/69 60/17697 0.2093 0.3675 0.3374 METTL1 1 MF GO:0005125 cytokine activity 2/69 220/17697 0.2117 0.3675 0.3374 CCL8/IFNE 2 MF GO:0043175 RNA polymerase core enzyme binding 1/69 61/17697 0.2124 0.3675 0.3374 GTF2E1 1 MF GO:0004860 protein kinase inhibitor activity 1/69 63/17697 0.2185 0.3692 0.3389 ITPRIP 1 MF GO:0033293 monocarboxylic acid binding 1/69 64/17697 0.2216 0.3692 0.3389 RXRA 1 MF GO:0005539 glycosaminoglycan binding 2/69 229/17697 0.2246 0.3692 0.3389 CCL8/LYVE1 2 MF GO:0035064 methylated histone binding 1/69 65/17697 0.2246 0.3692 0.3389 ING4 1 MF GO:0140034 methylation-dependent protein binding 1/69 65/17697 0.2246 0.3692 0.3389 ING4 1 MF GO:0008173 RNA methyltransferase activity 1/69 66/17697 0.2276 0.3692 0.3389 METTL1 1 MF GO:0042379 chemokine receptor binding 1/69 66/17697 0.2276 0.3692 0.3389 CCL8 1 MF GO:0019210 kinase inhibitor activity 1/69 67/17697 0.2307 0.3707 0.3404 ITPRIP 1 MF GO:0003714 transcription corepressor activity 2/69 238/17697 0.2375 0.3783 0.3474 TDP2/ATN1 2 MF GO:0001098 basal transcription machinery binding 1/69 72/17697 0.2456 0.3834 0.352 GTF2E1 1 MF GO:0001099 basal RNA polymerase II transcription machinery binding 1/69 72/17697 0.2456 0.3834 0.352 GTF2E1 1 MF GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/69 73/17697 0.2486 0.3834 0.352 VNN1 1 MF GO:0015171 amino acid transmembrane transporter activity 1/69 74/17697 0.2515 0.3834 0.352 SLC7A8 1 MF GO:0019003 GDP binding 1/69 74/17697 0.2515 0.3834 0.352 PCK1 1 MF GO:0016835 carbon-oxygen lyase activity 1/69 75/17697 0.2544 0.3834 0.352 HACD3 1 MF GO:0070063 RNA polymerase binding 1/69 76/17697 0.2574 0.3834 0.352 GTF2E1 1 MF GO:1903231 mRNA binding involved in posttranscriptional gene silencing 2/69 252/17697 0.2577 0.3834 0.352 MIR34A/MIR32 2 MF GO:0030295 protein kinase activator activity 1/69 80/17697 0.2689 0.3935 0.3613 RGCC 1 MF GO:0046332 SMAD binding 1/69 80/17697 0.2689 0.3935 0.3613 RGCC 1 MF GO:0004527 exonuclease activity 1/69 81/17697 0.2718 0.3945 0.3622 TREX2 1 MF GO:0033613 activating transcription factor binding 1/69 85/17697 0.2831 0.4077 0.3743 IFI27 1 MF GO:0019209 kinase activator activity 1/69 86/17697 0.2859 0.4085 0.375 RGCC 1 MF GO:0048018 receptor ligand activity 3/69 482/17697 0.2901 0.4112 0.3776 CCL8/IFNE/UTS2B 3 MF GO:0005126 cytokine receptor binding 2/69 286/17697 0.3069 0.4298 0.3946 CCL8/IFNE 2 MF GO:0008081 phosphoric diester hydrolase activity 1/69 94/17697 0.308 0.4298 0.3946 TDP2 1 MF GO:0042277 peptide binding 2/69 295/17697 0.3199 0.4429 0.4066 SLC7A8/RXRA 2 MF GO:0004725 protein tyrosine phosphatase activity 1/69 100/17697 0.3241 0.4454 0.4089 SSH1 1 MF GO:0004620 phospholipase activity 1/69 102/17697 0.3294 0.4458 0.4093 ABHD16A 1 MF GO:0005549 odorant binding 1/69 102/17697 0.3294 0.4458 0.4093 OR5H1 1 MF GO:0003697 single-stranded DNA binding 1/69 113/17697 0.3578 0.4769 0.4378 TDP2 1 MF GO:0036459 thiol-dependent ubiquitinyl hydrolase activity 1/69 114/17697 0.3603 0.4769 0.4378 DESI2 1 MF GO:0101005 ubiquitinyl hydrolase activity 1/69 114/17697 0.3603 0.4769 0.4378 DESI2 1 MF GO:0008509 anion transmembrane transporter activity 2/69 327/17697 0.3654 0.48 0.4407 SLC7A8/MPC1 2 MF GO:0031490 chromatin DNA binding 1/69 119/17697 0.3728 0.4862 0.4464 RXRA 1 MF GO:0005179 hormone activity 1/69 122/17697 0.3801 0.4919 0.4516 UTS2B 1 MF GO:0019783 ubiquitin-like protein-specific protease activity 1/69 123/17697 0.3826 0.4919 0.4516 DESI2 1 MF GO:0016298 lipase activity 1/69 127/17697 0.3922 0.5007 0.4597 ABHD16A 1 MF GO:0033218 amide binding 2/69 356/17697 0.4056 0.5142 0.4721 SLC7A8/RXRA 2 MF GO:0019842 vitamin binding 1/69 138/17697 0.418 0.5258 0.4827 PDXDC1 1 MF GO:0042578 phosphoric ester hydrolase activity 2/69 367/17697 0.4206 0.5258 0.4827 TDP2/SSH1 2 MF GO:0140030 modification-dependent protein binding 1/69 144/17697 0.4315 0.5357 0.4919 ING4 1