ONTOLOGY	ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	qvalue	geneID	Count
KEGG	hsa04512	ECM-receptor interaction	28/975	88/8144	6.228e-07	0.0002012	0.0001737	ITGA6/LAMA4/ITGA4/COL1A1/THBS4/ITGA10/ITGB8/ITGAV/ITGA3/FREM1/ITGA9/COL4A2/COL9A3/ITGA11/FRAS1/COL2A1/FREM2/GP5/SV2A/COL9A1/COL6A3/THBS2/GP1BA/IBSP/DAG1/CHAD/COL6A1/COL6A2	28
KEGG	hsa04740	Olfactory transduction	83/975	440/8144	1.123e-05	0.001814	0.001566	OR5A2/OR13C3/OR6C70/OR6Y1/OR10A5/ARRB1/OR13C4/OR56A1/OR4D9/OR51G2/OR4D5/OR2AK2/OR51A7/OR10G4/OR5D13/OR8H2/OR5AN1/GNG7/OR4D11/OR2F2/OR1D2/OR10P1/OR4K15/OR6N1/OR6P1/OR14I1/OR6F1/OR4C13/OR6K2/OR5K3/ADCY3/OR52E2/OR10Z1/OR10X1/OR6N2/OR6K3/OR6C2/OR51F1/OR10S1/OR2B2/OR2T10/PRKG2/OR51S1/OR13C8/OR3A1/OR52N1/OR10AG1/OR6C76/OR8B8/OR13G1/OR4C15/OR51D1/OR8B12/OR5AK2/OR52D1/OR6K6/OR5K4/OR8B2/OR13D1/OR5T2/OR2A1/OR2W1/OR51B5/OR10J5/OR6M1/OR52A1/OR5T3/OR51L1/OR5M11/OR56B4/OR5H2/OR1J1/OR5H14/OR4K17/OR5B2/OR6C6/OR52J3/OR8H3/OR2T3/OR6C4/OR5AS1/OR4E2/OR51V1	83
KEGG	hsa04915	Estrogen signaling pathway	34/975	138/8144	2.487e-05	0.002678	0.002313	HBEGF/KRT27/KRT31/KCNJ9/MAPK3/AKT2/OPRM1/KRT23/KRT26/PLCB1/PLCB3/KRT36/ESR1/ADCY3/KRT19/CREB1/CREB3L1/KRT35/TGFA/MMP2/CREB5/RARA/ADCY9/KRT18/POMC/BCL2/KRT37/KRT38/PIK3R3/NOS3/GRM1/KRT34/KRT33A/PIK3CB	34
KEGG	hsa04657	IL-17 signaling pathway	25/975	94/8144	7.699e-05	0.006217	0.005369	USP25/MAPK3/S100A9/TRADD/FOSL1/CXCL1/CCL2/TRAF5/IFNG/MMP3/CXCL10/TRAF2/S100A7/MAPK4/JUND/TRAF3/IL17D/S100A8/TNFAIP3/IL17RA/CXCL3/DEFB4A/MMP13/MAPK7/CASP8	25
KEGG	hsa04668	TNF signaling pathway	28/975	112/8144	9.646e-05	0.006231	0.005381	MAPK3/AKT2/TRADD/CXCL1/LIF/CCL2/VEGFC/MAP3K14/TRAF5/ICAM1/MMP3/TNFRSF1B/CREB1/CXCL10/CREB3L1/TRAF2/CREB5/MAP3K8/FAS/MMP14/TRAF3/TNFAIP3/PIK3R3/CXCL3/JAG1/RIPK1/PIK3CB/CASP8	28
KEGG	hsa04974	Protein digestion and absorption	25/975	103/8144	0.0003667	0.01974	0.01705	COL1A1/COL16A1/CTRB1/PGA5/COL12A1/COL14A1/COL8A2/COL4A2/PRSS3/COL9A3/COL22A1/ATP1B4/PGA4/COL2A1/SLC6A19/PGA3/CELA2A/COL9A1/COL6A3/DPP4/COL28A1/KCNN4/COL5A3/COL6A1/COL6A2	25
KEGG	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	20/975	77/8144	0.0005472	0.02352	0.02031	ITGA6/ITGA4/ITGA10/ITGB8/ITGAV/ITGA3/ITGA9/CACNB2/ITGA11/SGCB/TCF7L2/RYR2/SGCA/CACNB1/CACNA2D2/CACNB3/CACNG3/TCF7/DAG1/CTNNA2	20
KEGG	hsa04928	Parathyroid hormone synthesis, secretion and action	25/975	106/8144	0.0005825	0.02352	0.02031	HBEGF/ARRB1/MAPK3/PLCB1/EGR1/PLCB3/PRKCA/AKAP13/SLC9A3R1/ADCY3/CREB1/CREB3L1/GNA11/CREB5/PRKCB/ADCY9/LRP5/MMP14/RXRA/JUND/BCL2/MEF2A/PDE4D/MMP13/MMP24	25
KEGG	hsa00830	Retinol metabolism	18/975	68/8144	0.0008011	0.02875	0.02483	UGT2A2/CYP2S1/UGT2A3/UGT1A1/ADH7/UGT2A1/ADH1C/UGT2B28/UGT2B10/RDH5/CYP2C8/CYP2B6/UGT2B15/CYP1A1/UGT2B4/UGT1A7/DHRS4/ALDH1A2	18
KEGG	hsa04151	PI3K-Akt signaling pathway	62/975	354/8144	0.001138	0.03106	0.02682	ITGA6/LAMA4/ITGA4/COL1A1/FGF5/PHLPP1/SGK1/THBS4/ITGA10/PTEN/MAPK3/AKT2/ITGB8/ITGAV/ITGA3/ITGA9/IL7R/PCK1/COL4A2/GNG2/GNG7/ANGPT1/VEGFC/PRKCA/CRTC2/COL9A3/ITGA11/BCL2L11/COL2A1/CREB1/CREB3L1/GNG10/TGFA/SYK/CREB5/COL9A1/RXRA/GH2/ANGPT2/BCL2/AREG/COL6A3/PPP2CA/THBS2/JAK2/TLR4/EIF4EBP1/PKN3/PIK3R3/IBSP/NOS3/ANGPT4/FGF7/FGF20/IFNAR2/FGFR2/PPP2R3A/CHAD/COL6A1/GNG3/PIK3CB/COL6A2	62
KEGG	hsa04926	Relaxin signaling pathway	28/975	129/8144	0.001147	0.03106	0.02682	COL1A1/INSL5/ARRB1/MAPK3/AKT2/PLCB1/PLCB3/COL4A2/GNG2/GNG7/VEGFC/PRKCA/EDNRB/ADCY3/CREB1/CREB3L1/GNG10/MMP2/CREB5/ADCY9/INSL3/PIK3R3/NOS3/MMP13/NOS1/GNG3/ACTA2/PIK3CB	28
KEGG	hsa05207	Chemical carcinogenesis - receptor activation	41/975	212/8144	0.001154	0.03106	0.02682	UGT2A2/FGF5/MIRLET7D/UGT2A3/ARRB1/MAPK3/AKT2/RB1/UGT1A1/CHRNB4/ADRB2/UGT2A1/ESR1/PRKCA/EPHX2/NR1I3/ADCY3/UGT2B28/UGT2B10/CREB1/CREB3L1/CREB5/PRKCB/ADCY9/EPHX4/CYP2B6/RXRA/UGT2B15/BCL2/CYP1A1/UGT2B4/JAK2/UGT1A7/EIF4EBP1/PIK3R3/AHR/JAG1/MIRLET7G/FGF7/FGF20/PIK3CB	41
KEGG	hsa04933	AGE-RAGE signaling pathway in diabetic complications	23/975	100/8144	0.001368	0.034	0.02936	COL1A1/MAPK3/AKT2/PLCB1/FOXO1/EGR1/PLCB3/CCL2/COL4A2/VEGFC/PRKCA/AGER/ICAM1/THBD/MMP2/PRKCB/BCL2/SMAD3/JAK2/PIK3R3/TGFB3/NOS3/PIK3CB	23
KEGG	hsa04976	Bile secretion	21/975	89/8144	0.001548	0.03571	0.03084	SCT/SLC22A1/UGT2A2/UGT2A3/UGT1A1/KCNN2/UGT2A1/ADCY3/ATP1B4/UGT2B28/UGT2B10/CFTR/SLC5A1/ADCY9/SLC2A1/RXRA/UGT2B15/UGT2B4/UGT1A7/ABCB11/SLC9A1	21
KEGG	hsa05414	Dilated cardiomyopathy	22/975	96/8144	0.001811	0.039	0.03368	ITGA6/ITGA4/ITGA10/ITGB8/ITGAV/ITGA3/TNNC1/ITGA9/CACNB2/ITGA11/SGCB/ADCY3/RYR2/SGCA/CACNB1/ADCY9/CACNA2D2/CACNB3/CACNG3/TNNT2/TGFB3/DAG1	22
KEGG	hsa04911	Insulin secretion	20/975	86/8144	0.002384	0.04813	0.04156	SNAP25/PLCB1/KCNN2/PLCB3/KCNU1/PRKCA/TRPM4/ADCY3/ATP1B4/CREB1/RYR2/CREB3L1/GNA11/KCNN1/CREB5/PRKCB/ADCY9/SLC2A1/KCNN4/KCNMB2	20
KEGG	hsa04510	Focal adhesion	38/975	201/8144	0.002618	0.04878	0.04212	ITGA6/LAMA4/ITGA4/COL1A1/THBS4/ITGA10/PTEN/MYL5/CAV1/MAPK3/AKT2/ITGB8/ITGAV/FLNB/ITGA3/FYN/ACTN1/ITGA9/COL4A2/DOCK1/VEGFC/PRKCA/CAV3/COL9A3/PPP1CC/ITGA11/COL2A1/PRKCB/COL9A1/BCL2/COL6A3/THBS2/PIK3R3/IBSP/CHAD/COL6A1/PIK3CB/COL6A2	38
KEGG	hsa04973	Carbohydrate digestion and absorption	13/975	47/8144	0.002718	0.04878	0.04212	TAS1R2/AKT2/PLCB1/PLCB3/AMY2A/ATP1B4/SI/SLC5A1/PRKCB/HKDC1/HK2/PIK3R3/PIK3CB	13
KEGG	hsa04371	Apelin signaling pathway	28/975	139/8144	0.003655	0.06132	0.05296	MAPK3/AKT2/PDE3B/MAP1LC3B2/PLCB1/EGR1/PLCB3/GNG2/GNG7/KLF2/ADCY3/RYR2/PPARGC1A/GNG10/PLIN1/ADCY9/MAP1LC3B/RRAS2/ADCY10/SMAD3/SPHK1/MEF2A/JAG1/NOS3/SLC9A1/NOS1/GNG3/ACTA2	28
KEGG	hsa05146	Amoebiasis	22/975	102/8144	0.004033	0.06132	0.05296	LAMA4/COL1A1/C8A/C8B/ACTN1/PLCB1/CXCL1/PLCB3/COL4A2/ITGAM/PRKCA/IFNG/GNA11/PRKCB/CD1A/SERPINB3/TLR4/PIK3R3/TGFB3/CXCL3/CD1C/PIK3CB	22
KEGG	hsa05150	Staphylococcus aureus infection	21/975	96/8144	0.004116	0.06132	0.05296	KRT27/KRT31/FPR2/KRT23/KRT26/C4A/KRT36/DEFA1/ITGAM/ICAM1/KRT19/KRT35/KRT18/FCGR2C/KRT37/FCGR3A/KRT38/DEFB4A/KRT34/FPR1/KRT33A	21
KEGG	hsa05410	Hypertrophic cardiomyopathy	20/975	90/8144	0.004177	0.06132	0.05296	ITGA6/ITGA4/ITGA10/ITGB8/ITGAV/ITGA3/TNNC1/ITGA9/CACNB2/ITGA11/SGCB/RYR2/SGCA/CACNB1/CACNA2D2/CACNB3/CACNG3/TNNT2/TGFB3/DAG1	20
KEGG	hsa04066	HIF-1 signaling pathway	23/975	109/8144	0.004434	0.06192	0.05347	HMOX1/PFKM/MAPK3/AKT2/PDHA2/HIF1A/ANGPT1/PRKCA/IFNG/ALDOB/PRKCB/SLC2A1/PGK2/HKDC1/ANGPT2/BCL2/HK2/TLR4/EIF4EBP1/PIK3R3/NOS3/ANGPT4/PIK3CB	23
KEGG	hsa00140	Steroid hormone biosynthesis	15/975	61/8144	0.004601	0.06192	0.05347	UGT2A2/UGT2A3/UGT1A1/UGT2A1/COMT/UGT2B28/UGT2B10/SRD5A2/UGT2B15/CYP1A1/CYP11A1/UGT2B4/UGT1A7/CYP7B1/AKR1C3	15
KEGG	hsa04514	Cell adhesion molecules	29/975	149/8144	0.005238	0.06767	0.05844	ITGA6/ITGA4/CTLA4/LRRC4C/CD276/CLDN11/ITGB8/ITGAV/NRXN1/SIGLEC1/ITGA9/CLDN16/ITGAM/ICAM2/ICAM3/ICAM1/PDCD1/ICOS/NCAM2/LRRC4/F11R/CLDN20/HLA-A/CD34/ESAM/VTCN1/ICOSLG/CLDN17/CLDN15	29
KEGG	hsa04621	NOD-like receptor signaling pathway	34/975	184/8144	0.006179	0.07676	0.06629	AIM2/MEFV/ANTXR2/PYCARD/MAPK3/MAP1LC3B2/CARD16/PLCB1/CXCL1/PLCB3/CCL2/NOD1/DEFA1/TRAF5/P2RX7/TRAF2/MAP1LC3B/TRAF3/BCL2/CARD6/TNFAIP3/TLR4/NLRP6/TRIP6/TXNIP/CXCL3/OAS1/CARD18/RIPK1/ATG12/DEFB4A/IFNAR2/NLRP1/CASP8	34
KEGG	hsa05165	Human papillomavirus infection	55/975	331/8144	0.006664	0.07758	0.067	ITGA6/LAMA4/ITGA4/COL1A1/WNT10B/THBS4/ITGA10/PTEN/MAPK3/AKT2/ITGB8/TRADD/RB1/ITGAV/AXIN2/ITGA3/RFNG/FOXO1/HES3/ITGA9/COL4A2/FZD10/COL9A3/ITGA11/SLC9A3R1/WNT3/TCF7L2/COL2A1/CREB1/CREB3L1/CREB5/FAS/HLA-A/COL9A1/ATP6V1H/TRAF3/COL6A3/PPP2CA/THBS2/HES5/EIF4EBP1/PIK3R3/ATP6V0A1/IBSP/HES6/JAG1/TCF7/IFNAR2/FZD8/PPP2R3A/CHAD/COL6A1/PIK3CB/COL6A2/CASP8	55
KEGG	hsa00053	Ascorbate and aldarate metabolism	9/975	30/8144	0.006725	0.07758	0.067	UGT2A2/UGT2A3/UGT1A1/UGT2A1/UGT2B28/UGT2B10/UGT2B15/UGT2B4/UGT1A7	9
KEGG	hsa04725	Cholinergic synapse	23/975	113/8144	0.007014	0.07812	0.06747	MAPK3/AKT2/CHRNB4/KCNJ18/FYN/PLCB1/PLCB3/GNG2/GNG7/PRKCA/ADCY3/CREB1/CREB3L1/GNG10/GNA11/CREB5/PRKCB/ADCY9/BCL2/JAK2/PIK3R3/GNG3/PIK3CB	23
KEGG	hsa04929	GnRH secretion	15/975	64/8144	0.007391	0.07957	0.06872	KCNJ9/ARRB1/MAPK3/AKT2/PLCB1/KCNN2/PLCB3/PRKCA/GNA11/KCNN1/PRKCB/KCNN4/HCN1/PIK3R3/PIK3CB	15
KEGG	hsa00980	Metabolism of xenobiotics by cytochrome P450	17/975	78/8144	0.009658	0.1006	0.08691	UGT2A2/CYP2S1/UGT2A3/UGT1A1/ALDH3B1/ADH7/UGT2A1/CYP2F1/ADH1C/UGT2B28/UGT2B10/CYP2B6/UGT2B15/CYP1A1/UGT2B4/UGT1A7/AKR7L	17
KEGG	hsa05032	Morphine addiction	19/975	91/8144	0.01031	0.1041	0.0899	GRK5/KCNJ9/ARRB1/PDE3B/OPRM1/GNG2/GNG7/PRKCA/ADCY3/PDE7A/GNG10/GABRR3/PRKCB/ADCY9/GABRA5/PDE4D/GABRG3/GABRB3/GNG3	19
KEGG	hsa04261	Adrenergic signaling in cardiomyocytes	28/975	150/8144	0.01068	0.1045	0.09026	MAPK3/AKT2/PLCB1/TNNC1/ADRB2/PLCB3/PRKCA/CACNB2/PPP1CC/PPP1R1A/ADCY3/ATP1B4/CREB1/RYR2/CREB3L1/CACNB1/CREB5/ADCY9/RAPGEF3/BCL2/CACNA2D2/PPP2CA/CACNB3/CACNG3/TNNT2/ATP2B2/SLC9A1/PPP2R3A	28
KEGG	hsa04970	Salivary secretion	19/975	93/8144	0.01298	0.1233	0.1065	PLCB1/DMBT1/ADRB2/PLCB3/STATH/AMY2A/PRKCA/ADCY3/ATP1B4/HTN3/PRKG2/PRKCB/ADCY9/KCNN4/MUC7/ATP2B2/SLC9A1/HTN1/NOS1	19
KEGG	hsa00650	Butanoate metabolism	8/975	28/8144	0.01419	0.131	0.1131	ABAT/OXCT1/ACAT2/EHHADH/ACSM2A/ACSM4/GAD2/ECHS1	8
KEGG	hsa04916	Melanogenesis	20/975	101/8144	0.01537	0.1353	0.1169	WNT10B/MAPK3/PLCB1/PLCB3/FZD10/MITF/PRKCA/WNT3/EDNRB/ADCY3/TCF7L2/CREB1/CREB3L1/PRKCB/TYRP1/ADCY9/POMC/ASIP/TCF7/FZD8	20
KEGG	hsa04060	Cytokine-cytokine receptor interaction	48/975	295/8144	0.01566	0.1353	0.1169	IL1RL1/IL32/IL1RN/TNFSF10/IL19/CXCL1/IL7R/LIF/CCL2/PF4/INHA/CCL26/CNTFR/CCR10/INHBC/IFNG/CCR7/EDA2R/TNFRSF1B/BMP2/CLCF1/CXCL16/CCL15/CXCL10/XCL2/IL23A/PPBP/FAS/TNFRSF11B/GDF2/GDF7/BMP7/CCL24/GH2/IL17D/IL31RA/TNFRSF9/CCR2/IL17RA/TGFB3/CXCL3/IL1RL2/IL36A/IFNAR2/BMP4/TNFRSF8/LEPR/IL23R	48
KEGG	hsa00040	Pentose and glucuronate interconversions	9/975	34/8144	0.01592	0.1353	0.1169	UGT2A2/UGT2A3/UGT1A1/UGT2A1/UGT2B28/UGT2B10/UGT2B15/UGT2B4/UGT1A7	9
KEGG	hsa05230	Central carbon metabolism in cancer	15/975	70/8144	0.01692	0.1376	0.1189	PFKM/PTEN/IDH2/MAPK3/AKT2/PDHA2/HIF1A/SLC2A1/HKDC1/NTRK3/PGAM1/HK2/PIK3R3/FGFR2/PIK3CB	15
KEGG	hsa04972	Pancreatic secretion	20/975	102/8144	0.01704	0.1376	0.1189	SCT/CTRB1/PNLIP/PLCB1/PLCB3/AMY2A/PRKCA/PRSS3/ADCY3/ATP1B4/RYR2/CFTR/CELA2A/PRKCB/ADCY9/CLCA1/PLA2G2D/ATP2B2/SLC9A1/PLA2G12A	20
KEGG	hsa04062	Chemokine signaling pathway	33/975	192/8144	0.01972	0.1554	0.1342	GRK5/ARRB1/MAPK3/AKT2/PLCB1/CXCL1/PLCB3/CCL2/GNG2/GNG7/PF4/ITK/CCL26/CCR10/CCR7/ADCY3/CXCL16/CCL15/CXCL10/XCL2/GNG10/PRKCB/ADCY9/PPBP/CCL24/ELMO1/RASGRP2/JAK2/PIK3R3/CCR2/CXCL3/GNG3/PIK3CB	33
KEGG	hsa04730	Long-term depression	13/975	60/8144	0.02308	0.1775	0.1533	MAPK3/PLCB1/PLCB3/PRKCA/PPP1R17/GNA11/PRKG2/PRKCB/CRH/PLA2G4B/PPP2CA/NOS1/GRM1	13
KEGG	hsa00010	Glycolysis / Gluconeogenesis	14/975	67/8144	0.02531	0.1901	0.1642	PFKM/ALDH3B1/ADH7/PDHA2/PCK1/ADH1C/ALDOB/PGK2/HKDC1/PGAM1/HK2/ADPGK/FBP2/ACSS1	14
KEGG	hsa00590	Arachidonic acid metabolism	13/975	61/8144	0.02623	0.1925	0.1663	PTGIS/GPX3/ALOX12B/EPHX2/CYP2C8/CYP2B6/PLA2G4B/PLA2G2D/TBXAS1/PLB1/CYP4F2/AKR1C3/PLA2G12A	13
KEGG	hsa04960	Aldosterone-regulated sodium reabsorption	9/975	37/8144	0.02726	0.1941	0.1676	SGK1/MAPK3/PRKCA/ATP1B4/SCNN1A/PRKCB/SLC9A3R2/PIK3R3/PIK3CB	9
KEGG	hsa00860	Porphyrin metabolism	10/975	43/8144	0.02765	0.1941	0.1676	UGT2A2/HMOX1/UGT2A3/UGT1A1/UGT2A1/UGT2B28/UGT2B10/UGT2B15/UGT2B4/UGT1A7	10
KEGG	hsa04670	Leukocyte transendothelial migration	21/975	114/8144	0.02831	0.1946	0.168	ITGA4/THY1/MYL5/CLDN11/ACTN1/CLDN16/ITGAM/ITK/PRKCA/ICAM1/F11R/CLDN20/MMP2/PRKCB/RAPGEF3/ESAM/PIK3R3/CLDN17/CLDN15/CTNNA2/PIK3CB	21
KEGG	hsa04380	Osteoclast differentiation	23/975	128/8144	0.02931	0.1973	0.1703	SOCS1/MAPK3/AKT2/FOSL1/FYN/ACP5/CTSK/SIRPG/MAP3K14/MITF/IFNG/SIRPA/CREB1/TRAF2/SYK/TNFRSF11B/JUND/FCGR2C/FCGR3A/TYROBP/PIK3R3/IFNAR2/PIK3CB	23
KEGG	hsa04918	Thyroid hormone synthesis	15/975	75/8144	0.03041	0.2004	0.1731	SLC26A4/DUOXA2/GPX3/PLCB1/PLCB3/DUOX2/PRKCA/ALB/ADCY3/ATP1B4/CREB1/CREB3L1/CREB5/PRKCB/ADCY9	15
KEGG	hsa04920	Adipocytokine signaling pathway	14/975	69/8144	0.03196	0.2064	0.1783	AKT2/TRADD/PCK1/ACSL1/TNFRSF1B/PPARGC1A/TRAF2/ACSBG2/SLC2A1/POMC/RXRA/JAK2/LEPR/IRS4	14
KEGG	hsa04713	Circadian entrainment	18/975	97/8144	0.03773	0.2344	0.2024	KCNJ9/MAPK3/PLCB1/PLCB3/GNG2/GNG7/PRKCA/ADCY3/CREB1/RYR2/GNG10/PRKG2/PRKCB/ADCY9/ADCY10/NOS1/MTNR1A/GNG3	18
KEGG	hsa05215	Prostate cancer	18/975	97/8144	0.03773	0.2344	0.2024	PTEN/MAPK3/AKT2/RB1/FOXO1/TCF7L2/MMP3/CREB1/CREB3L1/TGFA/CREB5/SRD5A2/BCL2/PIK3R3/INSRR/TCF7/FGFR2/PIK3CB	18
KEGG	hsa04310	Wnt signaling pathway	28/975	167/8144	0.03983	0.2427	0.2096	WNT10B/DAAM2/NFATC3/FOSL1/AXIN2/PLCB1/PLCB3/INVS/FZD10/PRKCA/CTBP2/TLE6/WNT3/TCF7L2/NFATC4/CTNNBIP1/VANGL1/PRKCB/LRP5/NOTUM/FRZB/SMAD3/SKP1/TLE3/TCF7/LGR6/FZD8/CXXC4	28
KEGG	hsa04071	Sphingolipid signaling pathway	21/975	119/8144	0.04293	0.2521	0.2178	SMPD2/PTEN/MAPK3/AKT2/TRADD/FYN/CERS3/PLCB1/PLCB3/CERS1/PRKCA/TRAF2/SPTLC1/PRKCB/BCL2/PPP2CA/SPHK1/PIK3R3/NOS3/PPP2R3A/PIK3CB	21
KEGG	hsa04935	Growth hormone synthesis, secretion and action	21/975	119/8144	0.04293	0.2521	0.2178	SOCS1/MAPK3/AKT2/PLCB1/PLCB3/PRKCA/MAP3K1/ADCY3/CREB1/CREB3L1/GNA11/CREB5/PRKCB/ADCY9/GH2/ADCY10/SOCS2/JAK2/PIK3R3/IRS4/PIK3CB	21
KEGG	hsa00982	Drug metabolism - cytochrome P450	14/975	72/8144	0.04417	0.2548	0.22	UGT2A2/UGT2A3/UGT1A1/ALDH3B1/ADH7/UGT2A1/ADH1C/UGT2B28/UGT2B10/CYP2C8/CYP2B6/UGT2B15/UGT2B4/UGT1A7	14
KEGG	hsa04152	AMPK signaling pathway	21/975	120/8144	0.04642	0.263	0.2271	PFKM/AKT2/FOXO1/PCK1/CRTC2/ULK1/SREBF1/CREB1/PPARGC1A/CREB3L1/CFTR/CREB5/CAB39/PPP2CA/EIF4EBP1/PIK3R3/FBP2/PPP2R3A/LEPR/IRS4/PIK3CB	21
KEGG	hsa04742	Taste transduction	16/975	86/8144	0.04723	0.263	0.2271	TAS2R1/TAS1R2/HTR3D/HTR1B/PLCB1/PLCB3/TAS2R20/SCNN1A/SCN9A/TAS2R30/TAS2R41/TAS1R1/P2RY4/GABRA5/PKD2L1/GRM1	16
KEGG	hsa04919	Thyroid hormone signaling pathway	21/975	121/8144	0.0501	0.2743	0.2369	MED13L/PFKM/MAPK3/AKT2/ITGAV/PLCB1/FOXO1/HIF1A/PLCB3/ESR1/PRKCA/ATP1B4/PRKCB/SLC2A1/RXRA/SLCO1C1/PIK3R3/SLC9A1/DIO2/BMP4/PIK3CB	21
KEGG	hsa04350	TGF-beta signaling pathway	17/975	94/8144	0.05263	0.2833	0.2447	GREM1/MAPK3/SMURF1/DCN/ID3/INHBC/IFNG/BMP2/FMOD/GDF7/BMP7/SMAD3/PPP2CA/SKP1/NBL1/TGFB3/BMP4	17
KEGG	hsa04726	Serotonergic synapse	20/975	115/8144	0.05393	0.2855	0.2466	KCNJ9/MAPK3/HTR3D/HTR1B/KCND2/PLCB1/TPH2/KCNN2/ALOX12B/PLCB3/GNG2/GNG7/PRKCA/GNG10/PRKCB/CYP2C8/RAPGEF3/PLA2G4B/GABRB3/GNG3	20
KEGG	hsa05167	Kaposi sarcoma-associated herpesvirus infection	31/975	194/8144	0.05586	0.291	0.2513	NFATC3/MAPK3/AKT2/TRADD/MAP1LC3B2/RB1/CXCL1/HIF1A/GNG2/GNG7/ICAM1/TCF7L2/NFATC4/CREB1/GNG10/TRAF2/SYK/MAPKAPK2/FAS/MAP1LC3B/HLA-A/TRAF3/ANGPT2/JAK2/PIK3R3/CXCL3/TCF7/IFNAR2/GNG3/PIK3CB/CASP8	31
KEGG	hsa04977	Vitamin digestion and absorption	6/975	24/8144	0.05886	0.3018	0.2606	LMBRD1/CUBN/PNLIP/APOB/SLC19A3/PLB1	6
KEGG	hsa04727	GABAergic synapse	16/975	89/8144	0.06158	0.3101	0.2678	ABAT/TRAK2/GNG2/GNG7/PRKCA/ADCY3/GNG10/GABRR3/PRKCB/ADCY9/GABRA5/GABRG3/GAD2/PLCL1/GABRB3/GNG3	16
KEGG	hsa04611	Platelet activation	21/975	124/8144	0.06241	0.3101	0.2678	FERMT3/COL1A1/MAPK3/AKT2/FYN/PLCB1/PLCB3/PPP1CC/ADCY3/PRKG2/SYK/GP5/ADCY9/PLA2G4B/RASGRP2/TBXAS1/PIK3R3/GP1BA/NOS3/STIM1/PIK3CB	21
KEGG	hsa04340	Hedgehog signaling pathway	11/975	56/8144	0.06528	0.3134	0.2707	BOC/ARRB1/SMURF1/GLI3/CSNK1G2/SPOP/DISP1/BCL2/HHIP/SUFU/EVC	11
KEGG	hsa04923	Regulation of lipolysis in adipocytes	11/975	56/8144	0.06528	0.3134	0.2707	AKT2/PDE3B/ADRB2/AQP7/ADCY3/PRKG2/PLIN1/ADCY9/PIK3R3/IRS4/PIK3CB	11
KEGG	hsa05143	African trypanosomiasis	8/975	37/8144	0.06748	0.3134	0.2707	LAMA4/PLCB1/PLCB3/PRKCA/IFNG/ICAM1/PRKCB/FAS	8
KEGG	hsa04064	NF-kappa B signaling pathway	18/975	104/8144	0.06756	0.3134	0.2707	TRADD/CXCL1/MAP3K14/TRAF5/ICAM1/EDA2R/TRAF2/SYK/PRKCB/MALT1/TRAF3/BCL2/TNFAIP3/TLR4/CXCL3/TRIM25/RIPK1/EDARADD	18
KEGG	hsa05217	Basal cell carcinoma	12/975	63/8144	0.06792	0.3134	0.2707	WNT10B/AXIN2/FZD10/GLI3/WNT3/TCF7L2/BMP2/HHIP/SUFU/TCF7/FZD8/BMP4	12
KEGG	hsa04962	Vasopressin-regulated water reabsorption	9/975	44/8144	0.07321	0.333	0.2876	DCTN2/ADCY3/CREB1/DYNC1I1/CREB3L1/CREB5/ADCY9/STX4/AQP2	9
KEGG	hsa04140	Autophagy - animal	23/975	141/8144	0.07494	0.3362	0.2903	AMBRA1/PTEN/MAPK3/AKT2/EIF2AK4/MAP1LC3B2/DAPK1/HIF1A/ATG9B/ULK1/RRAGA/MAP1LC3B/ERN1/BCL2/RRAS2/PPP2CA/VMP1/ULK2/PIK3R3/RAB33B/ATG12/IRS4/PIK3CB	23
KEGG	hsa05222	Small cell lung cancer	16/975	92/8144	0.07864	0.3479	0.3005	ITGA6/LAMA4/PTEN/AKT2/RB1/ITGAV/ITGA3/COL4A2/TRAF5/TRAF2/RXRA/TRAF3/BCL2/PIK3R3/BIRC7/PIK3CB	16
KEGG	hsa01521	EGFR tyrosine kinase inhibitor resistance	14/975	79/8144	0.08455	0.369	0.3187	PTEN/MAPK3/AKT2/NRG1/PRKCA/BCL2L11/TGFA/PRKCB/BCL2/JAK2/EIF4EBP1/PIK3R3/FGFR2/PIK3CB	14
KEGG	hsa04370	VEGF signaling pathway	11/975	59/8144	0.08859	0.3815	0.3295	MAPK3/AKT2/PRKCA/MAPKAPK2/PRKCB/PLA2G4B/MAPKAPK3/SPHK1/PIK3R3/NOS3/PIK3CB	11
KEGG	hsa04931	Insulin resistance	18/975	108/8144	0.09034	0.3839	0.3316	PTEN/AKT2/GFPT2/PYGB/FOXO1/PCK1/CRTC2/PPP1CC/SREBF1/CREB1/PPARGC1A/CREB3L1/CREB5/PRKCB/SLC2A1/PIK3R3/NOS3/PIK3CB	18
KEGG	hsa04930	Type II diabetes mellitus	9/975	46/8144	0.09197	0.3858	0.3332	SOCS1/MAPK3/MAFA/HKDC1/HK2/SOCS2/PIK3R3/IRS4/PIK3CB	9
KEGG	hsa04360	Axon guidance	28/975	182/8144	0.09652	0.3997	0.3452	NTN4/EPHA3/NFATC3/LRRC4C/SEMA4B/BOC/MYL5/MAPK3/FYN/PLXNC1/NCK2/SEMA3G/PRKCA/PLXNB1/LRRC4/UNC5D/NFATC4/EPHB2/DPYSL5/ABLIM2/GDF7/BMP7/SEMA6B/SEMA3D/PIK3R3/SRGAP1/EPHA6/PIK3CB	28
KEGG	hsa05221	Acute myeloid leukemia	12/975	67/8144	0.09863	0.4026	0.3477	MAPK3/AKT2/ZBTB16/ITGAM/RUNX1T1/TCF7L2/RUNX1/RARA/EIF4EBP1/PIK3R3/TCF7/PIK3CB	12
KEGG	hsa05205	Proteoglycans in cancer	31/975	205/8144	0.09973	0.4026	0.3477	HBEGF/COL1A1/LUM/WNT10B/CAV1/MAPK3/AKT2/ITGAV/FLNB/DCN/HIF1A/ESR1/FZD10/PRKCA/CAV3/CBL/CD63/PPP1CC/MIR21/WNT3/MMP2/PRKCB/FAS/IQGAP1/RRAS2/TLR4/PIK3R3/FRS2/SLC9A1/FZD8/PIK3CB	31
KEGG	hsa04921	Oxytocin signaling pathway	24/975	154/8144	0.105	0.4136	0.3572	KCNJ9/NFATC3/MAPK3/KCNJ18/PLCB1/PLCB3/OXTR/PRKCA/CACNB2/PPP1CC/ADCY3/NFATC4/MAP2K5/RYR2/CACNB1/PRKCB/ADCY9/PLA2G4B/CACNA2D2/CACNB3/CACNG3/NOS3/OXT/MAPK7	24
KEGG	hsa04728	Dopaminergic synapse	21/975	132/8144	0.105	0.4136	0.3572	KCNJ9/ARRB1/AKT2/PLCB1/PLCB3/GNG2/GNG7/COMT/PRKCA/PPP1CC/CREB1/CREB3L1/GNG10/CREB5/TH/PRKCB/PPP2CA/DRD4/PPP2R3A/GNG3/KIF5A	21
KEGG	hsa04625	C-type lectin receptor signaling pathway	17/975	104/8144	0.1119	0.4356	0.3762	NFATC3/PYCARD/MAPK3/AKT2/PLK3/MAP3K14/CLEC7A/NFATC4/IL23A/SYK/MAPKAPK2/MALT1/IL17D/RRAS2/PIK3R3/PIK3CB/CASP8	17
KEGG	hsa04080	Neuroactive ligand-receptor interaction	51/975	362/8144	0.1191	0.4526	0.3909	SCT/INSL5/NPFFR2/FPR2/OPRM1/CHRNB4/HTR1B/ADRB2/AVPR1A/P2RY11/CHRNA2/OXTR/P2RY6/GALR1/P2RX7/GRIN3B/PRSS3/UCN/EDNRB/NPBWR2/P2RX6/NMBR/LYPD6/GABRR3/LYPD6B/QRFPR/PATE4/POMC/CRH/PTH2/P2RX5/NMS/GH2/INSL3/P2RY4/BRS3/GLRA1/HCRT/GABRA5/GLP2R/NTS/GRIK4/DRD4/GABRG3/GRM1/OXT/GABRB3/FPR1/NTSR2/LEPR/MTNR1A	51
KEGG	hsa05226	Gastric cancer	23/975	149/8144	0.1195	0.4526	0.3909	FGF5/WNT10B/MAPK3/AKT2/RB1/AXIN2/FZD10/WNT3/TCF7L2/LRP5/RXRA/BCL2/SMAD3/PIK3R3/TGFB3/TCF7/FGF7/FGF20/FGFR2/CTNNA2/REG4/FZD8/PIK3CB	23
KEGG	hsa05160	Hepatitis C	24/975	157/8144	0.1232	0.4526	0.3909	MAPK3/AKT2/CLDN11/EIF2AK4/TRADD/RB1/CLDN16/IFNG/CXCL10/CLDN20/TRAF2/FAS/RXRA/TRAF3/PPP2CA/PIK3R3/OAS1/RIPK1/CLDN17/IFIT1B/IFNAR2/CLDN15/PIK3CB/CASP8	24
KEGG	hsa04917	Prolactin signaling pathway	12/975	70/8144	0.1264	0.4526	0.3909	SOCS1/MAPK3/AKT2/ESR1/CSN2/SOCS7/TH/SOCS2/JAK2/PIK3R3/CISH/PIK3CB	12
KEGG	hsa05206	MicroRNAs in cancer	44/975	310/8144	0.1284	0.4526	0.3909	MIR99A/MIRLET7C/HMOX1/MIRLET7D/MIR205/MIR326/MIR451A/SOCS1/PTEN/MAPK3/COMMD3-BMI1/MIR34C/MIR210/MIR30B/MIR155/MIR101-1/ST14/PRKCA/MIR128-1/SPRY2/MIR21/WNT3/BCL2L11/MIR200A/MIR135A2/MARCKS/PRKCB/MIR615/MIR335/FOXP1/BCL2/SLC7A1/MIR133B/CCNG1/PIK3R3/MIR125B2/MIRLET7G/MIR137/MIR23B/MIR15B/MIR375/MAPK7/PIK3CB/MIR103B2	44
KEGG	hsa04550	Signaling pathways regulating pluripotency of stem cells	22/975	143/8144	0.1289	0.4526	0.3909	WNT10B/MAPK3/AKT2/AXIN2/COMMD3-BMI1/LIF/ID3/ESRRB/FZD10/INHBC/WNT3/SOX2/SKIL/SMAD3/JAK2/PIK3R3/TCF7/FGFR2/ZFHX3/FZD8/BMP4/PIK3CB	22
KEGG	hsa00350	Tyrosine metabolism	7/975	36/8144	0.1316	0.4526	0.3909	ALDH3B1/ADH7/HPD/COMT/ADH1C/TH/TYRP1	7
KEGG	hsa00515	Mannose type O-glycan biosynthesis	5/975	23/8144	0.1322	0.4526	0.3909	POMT2/CHST10/POMGNT1/MGAT5B/FUT9	5
KEGG	hsa04724	Glutamatergic synapse	18/975	114/8144	0.1328	0.4526	0.3909	SLC17A7/MAPK3/SLC1A2/PLCB1/PLCB3/GNG2/GNG7/PRKCA/GRIN3B/ADCY3/GNG10/PRKCB/ADCY9/PLA2G4B/SHANK2/GRIK4/GRM1/GNG3	18
KEGG	hsa04012	ErbB signaling pathway	14/975	85/8144	0.1335	0.4526	0.3909	HBEGF/MAPK3/AKT2/NCK2/NRG1/PRKCA/CBL/TGFA/PRKCB/AREG/EIF4EBP1/PIK3R3/PIK3CB/BTC	14
KEGG	hsa04922	Glucagon signaling pathway	17/975	107/8144	0.1355	0.4526	0.3909	PFKM/AKT2/PDE3B/PYGB/PLCB1/FOXO1/PDHA2/PLCB3/PCK1/CRTC2/CREB1/PPARGC1A/CREB3L1/CREB5/SLC2A1/PGAM1/FBP2	17
KEGG	hsa00120	Primary bile acid biosynthesis	4/975	17/8144	0.1372	0.4526	0.3909	HSD3B7/AMACR/ACOX2/CYP7B1	4
KEGG	hsa00910	Nitrogen metabolism	4/975	17/8144	0.1372	0.4526	0.3909	CA4/CA9/CA12/CA5B	4
KEGG	hsa04061	Viral protein interaction with cytokine and cytokine receptor	16/975	100/8144	0.1381	0.4526	0.3909	TNFSF10/IL19/CXCL1/CCL2/PF4/CCL26/CCR10/CCR7/TNFRSF1B/CCL15/CXCL10/XCL2/PPBP/CCL24/CCR2/CXCL3	16
KEGG	hsa04910	Insulin signaling pathway	21/975	137/8144	0.1392	0.4526	0.3909	SOCS1/MAPK3/AKT2/PDE3B/PYGB/FOXO1/SORBS1/PCK1/SH2B2/CBL/PPP1CC/SREBF1/PPARGC1A/HKDC1/HK2/SOCS2/EIF4EBP1/PIK3R3/FBP2/IRS4/PIK3CB	21
KEGG	hsa04912	GnRH signaling pathway	15/975	93/8144	0.1406	0.4526	0.3909	HBEGF/MAPK3/PLCB1/EGR1/PLCB3/PRKCA/MAP3K1/ADCY3/GNA11/MMP2/PRKCB/ADCY9/MMP14/PLA2G4B/MAPK7	15
KEGG	hsa05323	Rheumatoid arthritis	15/975	93/8144	0.1406	0.4526	0.3909	CTLA4/ACP5/CXCL1/CTSK/CCL2/ANGPT1/IFNG/ICAM1/MMP3/IL23A/ATP6V1H/TLR4/TGFB3/ATP6V0A1/CXCL3	15
KEGG	hsa00020	Citrate cycle (TCA cycle)	6/975	30/8144	0.1415	0.4526	0.3909	IDH2/PC/FH/PDHA2/PCK1/OGDH	6
KEGG	hsa04068	FoxO signaling pathway	20/975	131/8144	0.1503	0.4714	0.4071	SGK1/PTEN/MAPK3/AKT2/TNFSF10/FOXO1/IL7R/PLK3/PCK1/KLF2/BCL2L11/SMAD3/PIK3R3/TGFB3/FBXO32/CCNB3/ATG12/GRM1/IRS4/PIK3CB	20
KEGG	hsa04650	Natural killer cell mediated cytotoxicity	20/975	131/8144	0.1503	0.4714	0.4071	NCR2/RAET1E/MAPK3/TNFSF10/FYN/HCST/PRKCA/ICAM2/IFNG/ICAM1/SYK/PRKCB/FAS/HLA-A/FCGR3A/TYROBP/PIK3R3/KLRC2/IFNAR2/PIK3CB	20
KEGG	hsa05417	Lipid and atherosclerosis	31/975	215/8144	0.1553	0.4782	0.413	NFATC3/PYCARD/MAPK3/AKT2/TNFSF10/PLCB1/CXCL1/PLCB3/CCL2/PRKCA/AGER/APOB/ICAM1/MMP3/TRAF2/FAS/CYP2C8/CYP2B6/ERN1/RXRA/TRAF3/BCL2/CYP1A1/JAK2/TLR4/PIK3R3/CXCL3/NOS3/PIK3CB/CASP8/MIB2	31
KEGG	hsa00983	Drug metabolism - other enzymes	13/975	80/8144	0.1555	0.4782	0.413	UGT2A2/UGT2A3/UGT1A1/UGT2A1/TK1/CES1/UGT2B28/UGT2B10/DUT/UGT2B15/UGT2B4/TYMP/UGT1A7	13
KEGG	hsa00061	Fatty acid biosynthesis	4/975	18/8144	0.1606	0.4894	0.4226	ACSL1/ACSBG2/OLAH/CBR4	4
KEGG	hsa04540	Gap junction	14/975	88/8144	0.1629	0.4916	0.4246	MAPK3/PLCB1/PLCB3/PRKCA/ADCY3/MAP2K5/GNA11/PRKG2/PRKCB/ADCY9/TUBA3C/GRM1/TUBB4A/MAPK7	14
KEGG	hsa05163	Human cytomegalovirus infection	32/975	225/8144	0.1702	0.509	0.4396	NFATC3/MAPK3/AKT2/TRADD/RB1/ITGAV/PLCB1/PLCB3/CCL2/GNG2/GNG7/TRAF5/PRKCA/AKAP13/ADCY3/NFATC4/CREB1/CREB3L1/GNG10/TRAF2/GNA11/CREB5/PRKCB/ADCY9/FAS/HLA-A/EIF4EBP1/PIK3R3/RIPK1/GNG3/PIK3CB/CASP8	32
KEGG	hsa00592	alpha-Linolenic acid metabolism	5/975	25/8144	0.1719	0.5095	0.44	FADS2/PLA2G4B/PLA2G2D/PLB1/PLA2G12A	5
KEGG	hsa04660	T cell receptor signaling pathway	16/975	104/8144	0.1752	0.5145	0.4444	CTLA4/NFATC3/GRAP2/MAPK3/AKT2/FYN/NCK2/MAP3K14/ITK/IFNG/PDCD1/ICOS/MAP3K8/MALT1/PIK3R3/PIK3CB	16
KEGG	hsa03320	PPAR signaling pathway	12/975	75/8144	0.1811	0.5271	0.4552	SORBS1/PCK1/ACOX2/FADS2/ACSL1/GK2/AQP7/EHHADH/ACSBG2/PLIN1/RXRA/LPL	12
KEGG	hsa00620	Pyruvate metabolism	8/975	47/8144	0.1942	0.5508	0.4757	PC/FH/ADH7/PDHA2/PCK1/ADH1C/ACAT2/ACSS1	8
KEGG	hsa04024	cAMP signaling pathway	31/975	221/8144	0.1959	0.5508	0.4757	MAPK3/AKT2/PDE3B/CNGB3/HTR1B/ADRB2/OXTR/GLI3/GRIN3B/FXYD1/PPP1CC/ADCY3/ATP1B4/CREB1/RYR2/CREB3L1/CFTR/CREB5/ADCY9/POMC/CRH/RAPGEF3/RRAS2/HHIP/ADCY10/PIK3R3/ATP2B2/PDE4D/SLC9A1/OXT/PIK3CB	31
KEGG	hsa00051	Fructose and mannose metabolism	6/975	33/8144	0.196	0.5508	0.4757	PFKM/ALDOB/HKDC1/HK2/GMPPB/FBP2	6
KEGG	hsa04022	cGMP-PKG signaling pathway	24/975	167/8144	0.1967	0.5508	0.4757	NFATC3/MAPK3/AKT2/PDE3B/PLCB1/ADRB2/PLCB3/KCNU1/PPP1CC/EDNRB/ADCY3/ATP1B4/NFATC4/CREB1/CREB3L1/GNA11/PRKG2/CREB5/ADCY9/MEF2A/KCNMB2/ATP2B2/NOS3/IRS4	24
KEGG	hsa05204	Chemical carcinogenesis - DNA adducts	11/975	69/8144	0.1978	0.5508	0.4757	UGT2A2/UGT2A3/UGT1A1/UGT2A1/UGT2B28/UGT2B10/CYP2C8/UGT2B15/CYP1A1/UGT2B4/UGT1A7	11
KEGG	hsa01200	Carbon metabolism	17/975	115/8144	0.2106	0.5783	0.4994	PFKM/IDH2/PC/FH/PDHA2/ACAT2/OGDH/ALDOB/PGK2/HKDC1/PGAM1/HK2/AMT/ADPGK/FBP2/ACSS1/ECHS1	17
KEGG	hsa00100	Steroid biosynthesis	4/975	20/8144	0.2113	0.5783	0.4994	SQLE/LSS/DHCR24/SOAT1	4
KEGG	hsa04010	MAPK signaling pathway	40/975	294/8144	0.2131	0.5785	0.4996	FGF5/ELK4/NFATC3/ARRB1/MAPK3/AKT2/TRADD/FLNB/ANGPT1/VEGFC/MAP3K14/PRKCA/CACNB2/MAP3K1/MAP2K5/CACNB1/TGFA/TRAF2/MAPKAPK2/PRKCB/MAP3K8/FAS/PLA2G4B/JUND/ANGPT2/MAPKAPK3/RRAS2/AREG/MAPT/CACNA2D2/CACNB3/RASGRP2/CACNG3/DUSP7/TGFB3/ANGPT4/FGF7/FGF20/FGFR2/MAPK7	40
KEGG	hsa05418	Fluid shear stress and atherosclerosis	20/975	139/8144	0.2213	0.5958	0.5145	HMOX1/CAV1/AKT2/ITGAV/CCL2/KLF2/CAV3/IFNG/ICAM1/MAP2K5/THBD/MMP2/BCL2/MEF2A/PIK3R3/NOS3/BMP4/SUMO3/MAPK7/PIK3CB	20
KEGG	hsa05210	Colorectal cancer	13/975	86/8144	0.225	0.5993	0.5175	MAPK3/AKT2/AXIN2/TCF7L2/BCL2L11/TGFA/BCL2/AREG/SMAD3/PIK3R3/TGFB3/TCF7/PIK3CB	13
KEGG	hsa04934	Cushing syndrome	22/975	155/8144	0.2268	0.5993	0.5175	WNT10B/MAPK3/RB1/AXIN2/FH/PLCB1/PLCB3/FZD10/WNT3/ADCY3/TCF7L2/CREB1/CREB3L1/GNA11/CREB5/ADCY9/POMC/CRH/CYP11A1/AHR/TCF7/FZD8	22
KEGG	hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	3/975	14/8144	0.2303	0.5993	0.5175	CHST2/B3GNT7/CHST4	3
KEGG	hsa05164	Influenza A	24/975	171/8144	0.2312	0.5993	0.5175	PYCARD/TMPRSS4/MAPK3/AKT2/TRADD/TNFSF10/CCL2/PRKCA/PRSS3/IFNG/ICAM1/CXCL10/PRKCB/FAS/TRAF3/JAK2/TLR4/PIK3R3/TRIM25/OAS1/IFNAR2/PIK3CB/CASP8/TMPRSS11D	24
KEGG	hsa00380	Tryptophan metabolism	7/975	42/8144	0.2319	0.5993	0.5175	KMO/TPH2/INMT/ACAT2/EHHADH/CYP1A1/ECHS1	7
KEGG	hsa01212	Fatty acid metabolism	9/975	57/8144	0.2377	0.6093	0.5262	TECR/FADS2/ACSL1/ACAT2/EHHADH/ACSBG2/ELOVL5/ECHS1/CBR4	9
KEGG	hsa05144	Malaria	8/975	50/8144	0.2442	0.6212	0.5365	THBS4/CCL2/CR1/IFNG/ICAM1/THBS2/TLR4/TGFB3	8
KEGG	hsa04927	Cortisol synthesis and secretion	10/975	65/8144	0.2462	0.6213	0.5366	PLCB1/PLCB3/ADCY3/CREB1/CREB3L1/GNA11/CREB5/ADCY9/POMC/CYP11A1	10
KEGG	hsa00071	Fatty acid degradation	7/975	43/8144	0.2507	0.6228	0.5379	ADH7/ACSL1/ADH1C/ACAT2/EHHADH/ACSBG2/ECHS1	7
KEGG	hsa04936	Alcoholic liver disease	20/975	142/8144	0.2513	0.6228	0.5379	AKT2/TRADD/FOXO1/ADH7/CXCL1/C4A/MAP3K14/ADH1C/SREBF1/TCF7L2/PPARGC1A/FAS/TRAF3/TLR4/MIR217/IL17RA/CXCL3/TCF7/RIPK1/CASP8	20
KEGG	hsa05213	Endometrial cancer	9/975	58/8144	0.2539	0.6228	0.5379	PTEN/MAPK3/AKT2/AXIN2/TCF7L2/PIK3R3/TCF7/CTNNA2/PIK3CB	9
KEGG	hsa00500	Starch and sucrose metabolism	6/975	36/8144	0.2569	0.6228	0.5379	PYGB/AMY2A/SI/HKDC1/GBA3/HK2	6
KEGG	hsa00512	Mucin type O-glycan biosynthesis	6/975	36/8144	0.2569	0.6228	0.5379	GALNT12/ST6GALNAC4/C1GALT1/GALNT6/GALNT10/GCNT1	6
KEGG	hsa00330	Arginine and proline metabolism	8/975	51/8144	0.2618	0.6228	0.5379	GATM/ODC1/OAT/CKMT2/NOS3/P4HA1/NOS1/AGMAT	8
KEGG	hsa00591	Linoleic acid metabolism	5/975	29/8144	0.2622	0.6228	0.5379	CYP2C8/PLA2G4B/PLA2G2D/PLB1/PLA2G12A	5
KEGG	hsa04211	Longevity regulating pathway	13/975	89/8144	0.2639	0.6228	0.5379	AKT2/FOXO1/ULK1/ADCY3/CREB1/PPARGC1A/CREB3L1/CREB5/ADCY9/EIF4EBP1/PIK3R3/IRS4/PIK3CB	13
KEGG	hsa00730	Thiamine metabolism	3/975	15/8144	0.2642	0.6228	0.5379	AK1/AK4/AK2	3
KEGG	hsa04210	Apoptosis	19/975	136/8144	0.2703	0.6326	0.5463	MAPK3/AKT2/TP53AIP1/TRADD/TNFSF10/CTSK/MAP3K14/BCL2L11/TRAF2/FAS/ERN1/BCL2/PIK3R3/CTSC/RIPK1/TUBA3C/PIK3CB/SPTA1/CASP8	19
KEGG	hsa01522	Endocrine resistance	14/975	98/8144	0.281	0.6475	0.5592	HBEGF/MAPK3/AKT2/RB1/ESR1/ADCY3/MMP2/ADCY9/BCL2/PIK3R3/ABCB11/BIK/JAG1/PIK3CB	14
KEGG	hsa04925	Aldosterone synthesis and secretion	14/975	98/8144	0.281	0.6475	0.5592	PLCB1/PLCB3/PRKCA/ADCY3/ATP1B4/CREB1/CREB3L1/GNA11/CREB5/PRKCB/ADCY9/POMC/CYP11A1/ATP2B2	14
KEGG	hsa04020	Calcium signaling pathway	32/975	240/8144	0.2827	0.6475	0.5592	FGF5/PLCB1/TNNC1/ADRB2/AVPR1A/PLCB3/OXTR/VEGFC/TRDN/PRKCA/P2RX7/STIM2/EDNRB/ADCY3/P2RX6/RYR2/GNA11/PRKCB/ADCY9/GDNF/P2RX5/TPCN1/NTRK3/SPHK1/ATP2B2/NOS3/FGF7/FGF20/FGFR2/NOS1/STIM1/GRM1	32
KEGG	hsa05416	Viral myocarditis	9/975	60/8144	0.2872	0.6534	0.5642	CD55/CAV1/FYN/ICAM1/SGCB/SGCA/HLA-A/DAG1/CASP8	9
KEGG	hsa02010	ABC transporters	7/975	45/8144	0.2895	0.654	0.5648	ABCA9/ABCA6/CFTR/ABCC6/ABCB11/ABCA4/ABCA3	7
KEGG	hsa04630	JAK-STAT signaling pathway	22/975	162/8144	0.2958	0.6591	0.5692	SOCS1/AKT2/STAM2/IL19/IL7R/LIF/CNTFR/SOCS7/IFNG/GFAP/IL23A/GH2/IL17D/BCL2/SOCS2/JAK2/PIK3R3/IFNAR2/LEPR/CISH/IL23R/PIK3CB	22
KEGG	hsa05220	Chronic myeloid leukemia	11/975	76/8144	0.2979	0.6591	0.5692	MAPK3/AKT2/RB1/CBL/CTBP2/RUNX1/BCR/SMAD3/PIK3R3/TGFB3/PIK3CB	11
KEGG	hsa04961	Endocrine and other factor-regulated calcium reabsorption	8/975	53/8144	0.2979	0.6591	0.5692	PLCB1/PLCB3/ESR1/PRKCA/ATP1B4/PRKCB/ADCY9/ATP2B2	8
KEGG	hsa05224	Breast cancer	20/975	147/8144	0.3046	0.6694	0.5781	FGF5/WNT10B/PTEN/MAPK3/AKT2/RB1/AXIN2/ESR1/FZD10/WNT3/TCF7L2/LRP5/HES5/PIK3R3/JAG1/TCF7/FGF7/FGF20/FZD8/PIK3CB	20
KEGG	hsa00410	beta-Alanine metabolism	5/975	31/8144	0.3109	0.6784	0.5859	ABAT/ALDH3B1/EHHADH/GAD2/ECHS1	5
KEGG	hsa05140	Leishmaniasis	11/975	77/8144	0.3133	0.6791	0.5865	ITGA4/MAPK3/CR1/ITGAM/IFNG/PRKCB/FCGR2C/FCGR3A/JAK2/TLR4/TGFB3	11
KEGG	hsa05170	Human immunodeficiency virus 1 infection	28/975	212/8144	0.3175	0.6838	0.5905	NFATC3/MAPK3/AKT2/TRADD/GNG2/GNG7/TRAF5/APOBEC3D/PRKCA/AP1G1/APOBEC3G/TNFRSF1B/NFATC4/GNG10/TRAF2/GNA11/PRKCB/FAS/HLA-A/BCL2/SKP1/TLR4/PIK3R3/CCNB3/RIPK1/GNG3/PIK3CB/CASP8	28
KEGG	hsa00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	4/975	24/8144	0.3221	0.6891	0.5951	HS3ST5/XYLT1/EXTL2/EXT2	4
KEGG	hsa04390	Hippo signaling pathway	21/975	157/8144	0.3272	0.6953	0.6005	WNT10B/LIMD1/AXIN2/TP73/FZD10/PPP1CC/WNT3/TCF7L2/BMP2/SOX2/GDF7/BMP7/FRMD6/AREG/SMAD3/PPP2CA/TGFB3/TCF7/CTNNA2/FZD8/BMP4	21
KEGG	hsa00514	Other types of O-glycan biosynthesis	7/975	47/8144	0.3296	0.6959	0.601	GALNT12/C1GALT1/GALNT6/RFNG/POMT2/GALNT10/GXYLT2	7
KEGG	hsa05142	Chagas disease	14/975	102/8144	0.3346	0.6992	0.6039	MAPK3/AKT2/PLCB1/PLCB3/CCL2/IFNG/GNA11/FAS/PPP2CA/TLR4/PIK3R3/TGFB3/PIK3CB/CASP8	14
KEGG	hsa00640	Propanoate metabolism	5/975	32/8144	0.3356	0.6992	0.6039	ABAT/EHHADH/BCKDHB/ACSS1/ECHS1	5
KEGG	hsa04270	Vascular smooth muscle contraction	18/975	134/8144	0.3377	0.6992	0.6039	MAPK3/PLCB1/AVPR1A/PLCB3/KCNU1/RAMP1/PRKCA/PPP1CC/ADCY3/GNA11/PRKCB/ADCY9/PLA2G4B/PLA2G2D/KCNMB2/PRKCH/ACTA2/PLA2G12A	18
KEGG	hsa04520	Adherens junction	10/975	71/8144	0.3422	0.7021	0.6064	MAPK3/FYN/ACTN1/SORBS1/TCF7L2/IQGAP1/SMAD3/TCF7/CTNNA2/BAIAP2	10
KEGG	hsa05033	Nicotine addiction	6/975	40/8144	0.3442	0.7021	0.6064	SLC17A7/GRIN3B/GABRR3/GABRA5/GABRG3/GABRB3	6
KEGG	hsa04260	Cardiac muscle contraction	12/975	87/8144	0.3462	0.7021	0.6064	TNNC1/TRDN/CACNB2/ATP1B4/RYR2/CACNB1/CACNA2D2/CACNB3/CACNG3/TNNT2/UQCRH/SLC9A1	12
KEGG	hsa05017	Spinocerebellar ataxia	19/975	143/8144	0.3497	0.7021	0.6064	AMBRA1/AKT2/PLCB1/PSMD9/PLCB3/PSMB7/PRKCA/ULK1/GRIN3B/PSMA7/TRAF2/ATXN2/PRKCB/ERN1/ULK2/PIK3R3/DAB1/GRM1/PIK3CB	19
KEGG	hsa00280	Valine, leucine and isoleucine degradation	7/975	48/8144	0.35	0.7021	0.6064	ABAT/OXCT1/ACAT2/EHHADH/HIBADH/BCKDHB/ECHS1	7
KEGG	hsa05218	Melanoma	10/975	72/8144	0.3589	0.7087	0.6121	FGF5/PTEN/MAPK3/AKT2/RB1/MITF/PIK3R3/FGF7/FGF20/PIK3CB	10
KEGG	hsa05223	Non-small cell lung cancer	10/975	72/8144	0.3589	0.7087	0.6121	MAPK3/AKT2/RB1/PRKCA/TGFA/PRKCB/RXRA/PIK3R3/KIF5A/PIK3CB	10
KEGG	hsa05225	Hepatocellular carcinoma	22/975	168/8144	0.3598	0.7087	0.6121	HMOX1/WNT10B/PTEN/MAPK3/AKT2/RB1/AXIN2/BRD7/FZD10/PRKCA/WNT3/TCF7L2/TGFA/PRKCB/LRP5/SMAD3/ACTL6A/PIK3R3/TGFB3/TCF7/FZD8/PIK3CB	22
KEGG	hsa05219	Bladder cancer	6/975	41/8144	0.3666	0.7176	0.6198	HBEGF/MAPK3/RB1/DAPK1/MMP2/TYMP	6
KEGG	hsa04810	Regulation of actin cytoskeleton	28/975	218/8144	0.3747	0.7281	0.6288	ITGA6/ITGA4/FGF5/ITGA10/MYL5/MAPK3/ITGB8/ITGAV/ITGA3/ACTN1/ITGA9/PFN4/DOCK1/ITGAM/PPP1CC/ITGA11/SCIN/IQGAP1/RRAS2/ARHGEF7/PIK3R3/INSRR/SLC9A1/FGF7/FGF20/FGFR2/BAIAP2/PIK3CB	28
KEGG	hsa04666	Fc gamma R-mediated phagocytosis	13/975	97/8144	0.3764	0.7281	0.6288	MAPK3/AKT2/DOCK1/PRKCA/MARCKS/SYK/PRKCB/SCIN/PLA2G4B/FCGR3A/SPHK1/PIK3R3/PIK3CB	13
KEGG	hsa00790	Folate biosynthesis	4/975	26/8144	0.3794	0.7294	0.6299	TPH2/MOCOS/TH/AKR1C3	4
KEGG	hsa05161	Hepatitis B	21/975	162/8144	0.383	0.732	0.6321	NFATC3/MAPK3/AKT2/RB1/PRKCA/MAP3K1/NFATC4/CREB1/CREB3L1/CREB5/PRKCB/FAS/TRAF3/BCL2/SMAD3/JAK2/TLR4/PIK3R3/TGFB3/PIK3CB/CASP8	21
KEGG	hsa04662	B cell receptor signaling pathway	11/975	82/8144	0.3922	0.7452	0.6436	NFATC3/MAPK3/AKT2/IFITM1/SYK/PRKCB/CD79B/MALT1/PIK3R3/CD72/PIK3CB	11
KEGG	hsa04640	Hematopoietic cell lineage	13/975	99/8144	0.4057	0.7574	0.6541	ITGA6/ITGA4/CD55/CD9/ITGA3/IL7R/CR1/ITGAM/GP5/CD1A/CD34/GP1BA/CD1C	13
KEGG	hsa04150	mTOR signaling pathway	20/975	156/8144	0.4074	0.7574	0.6541	WNT10B/SGK1/PTEN/MAPK3/AKT2/FZD10/PRKCA/ULK1/WNT3/PRKCB/LRP5/RRAGA/CAB39/ATP6V1H/FNIP2/EIF4EBP1/ULK2/PIK3R3/FZD8/PIK3CB	20
KEGG	hsa00062	Fatty acid elongation	4/975	27/8144	0.4079	0.7574	0.6541	TECR/THEM5/ELOVL5/ECHS1	4
KEGG	hsa04723	Retrograde endocannabinoid signaling	19/975	148/8144	0.4092	0.7574	0.6541	SLC17A7/KCNJ9/MAPK3/PLCB1/PLCB3/GNG2/GNG7/NDUFS2/PRKCA/ADCY3/GNG10/GABRR3/PRKCB/ADCY9/GABRA5/GABRG3/GRM1/GABRB3/GNG3	19
KEGG	hsa04720	Long-term potentiation	9/975	67/8144	0.4104	0.7574	0.6541	MAPK3/PLCB1/PLCB3/PRKCA/PPP1CC/PPP1R1A/PRKCB/RAPGEF3/GRM1	9
KEGG	hsa04978	Mineral absorption	8/975	60/8144	0.4302	0.7895	0.6818	HMOX1/STEAP1/STEAP2/ATP1B4/SLC6A19/SLC5A1/S100G/ATP2B2	8
KEGG	hsa04610	Complement and coagulation cascades	11/975	85/8144	0.4403	0.8035	0.6939	CD55/C8A/C8B/VSIG4/C4A/CR1/ITGAM/A2M/C4BPB/THBD/CFHR4	11
KEGG	hsa05211	Renal cell carcinoma	9/975	69/8144	0.4461	0.8095	0.6991	MAPK3/AKT2/FH/HIF1A/TGFA/SLC2A1/PIK3R3/TGFB3/PIK3CB	9
KEGG	hsa04015	Rap1 signaling pathway	26/975	210/8144	0.459	0.8188	0.7071	FGF5/SIPA1L1/MAPK3/AKT2/PLCB1/PFN4/PLCB3/DOCK4/ANGPT1/VEGFC/ITGAM/PRKCA/ADCY3/PRKCB/ADCY9/SKAP1/RAPGEF3/ANGPT2/RASGRP2/PIK3R3/ANGPT4/FGF7/FGF20/FGFR2/FPR1/PIK3CB	26
KEGG	hsa01250	Biosynthesis of nucleotide sugars	5/975	37/8144	0.4598	0.8188	0.7071	GFPT2/UAP1/HKDC1/HK2/GMPPB	5
KEGG	hsa04622	RIG-I-like receptor signaling pathway	9/975	70/8144	0.4638	0.8188	0.7071	TRADD/MAP3K1/CXCL10/TRAF2/TRAF3/TRIM25/RIPK1/ATG12/CASP8	9
KEGG	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	9/975	70/8144	0.4638	0.8188	0.7071	HBEGF/CXCL1/NOD1/MAP3K14/F11R/IGSF5/ATP6V1H/ATP6V0A1/CXCL3	9
KEGG	hsa04392	Hippo signaling pathway - multiple species	4/975	29/8144	0.4639	0.8188	0.7071	FAT4/LIMD1/FRMD6/DCHS1	4
KEGG	hsa04620	Toll-like receptor signaling pathway	13/975	104/8144	0.4789	0.8407	0.7261	MAPK3/AKT2/CTSK/CXCL10/TLR8/MAP3K8/TRAF3/TLR4/PIK3R3/RIPK1/IFNAR2/PIK3CB/CASP8	13
KEGG	hsa00030	Pentose phosphate pathway	4/975	30/8144	0.4912	0.8483	0.7326	PFKM/DERA/ALDOB/FBP2	4
KEGG	hsa05152	Tuberculosis	22/975	180/8144	0.4933	0.8483	0.7326	MAPK3/AKT2/TRADD/PLK3/CR1/ITGAM/IFNG/CLEC7A/CREB1/IL23A/SYK/MALT1/ATP6V1H/BCL2/FCGR2C/FCGR3A/SPHK1/JAK2/TLR4/TGFB3/ATP6V0A1/CASP8	22
KEGG	hsa05131	Shigellosis	30/975	247/8144	0.4961	0.8483	0.7326	PYCARD/MYL5/MAPK3/AKT2/TRADD/MAP1LC3B2/ACTN1/PLCB1/FOXO1/PFN4/PLCB3/NOD1/DOCK1/TRAF5/TRAF2/RRAGA/MAP1LC3B/HKDC1/MALT1/FNBP1/BCL2/CBX3/HK2/ELMO1/SKP1/TLR4/PIK3R3/RIPK1/ATG12/PIK3CB	30
KEGG	hsa05166	Human T-cell leukemia virus 1 infection	27/975	222/8144	0.4964	0.8483	0.7326	ELK4/NFATC3/PTEN/BUB3/MAPK3/AKT2/RB1/FOSL1/EGR1/MAP3K14/CRTC2/ICAM1/MAP3K1/ADCY3/CDC20/NFATC4/CREB1/CREB3L1/CREB5/ADCY9/SLC2A1/HLA-A/SMAD3/ETS2/PIK3R3/TGFB3/PIK3CB	27
KEGG	hsa04070	Phosphatidylinositol signaling system	12/975	97/8144	0.4984	0.8483	0.7326	IMPA1/PTEN/PLCB1/SYNJ2/PLCB3/SACM1L/PRKCA/PRKCB/PIK3R3/IP6K3/PIK3C2G/PIK3CB	12
KEGG	hsa04137	Mitophagy - animal	9/975	72/8144	0.499	0.8483	0.7326	AMBRA1/MAP1LC3B2/HIF1A/ATG9B/MITF/ULK1/MAP1LC3B/RRAS2/TAX1BP1	9
KEGG	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	11/975	89/8144	0.5039	0.8521	0.7359	NFATC3/PTEN/MAPK3/AKT2/HIF1A/IFNG/PDCD1/JAK2/TLR4/PIK3R3/PIK3CB	11
KEGG	hsa04014	Ras signaling pathway	28/975	232/8144	0.5127	0.8621	0.7445	FGF5/RASAL2/MAPK3/AKT2/GNG2/GNG7/ANGPT1/VEGFC/PRKCA/GNG10/TGFA/PRKCB/EXOC2/PLA2G4B/ANGPT2/RRAS2/PLA2G2D/RASGRP2/ETS2/PIK3R3/ANGPT4/FGF7/FGF20/FGFR2/SHOC2/GNG3/PIK3CB/PLA2G12A	28
KEGG	hsa05132	Salmonella infection	30/975	249/8144	0.5151	0.8621	0.7445	RHOJ/PYCARD/MYL5/MAPK3/AKT2/TRADD/TNFSF10/FLNB/PFN4/NOD1/DCTN2/TCF7L2/DYNC1I1/SNX9/TRAF2/VPS18/EXOC2/BCL2/ELMO1/SKP1/SNX18/TLR4/PIK3C2G/TCF7/RIPK1/TUBA3C/TUBB4A/KIF5A/PIK3CB/CASP8	30
KEGG	hsa00052	Galactose metabolism	4/975	31/8144	0.5179	0.8623	0.7447	PFKM/SI/HKDC1/HK2	4
KEGG	hsa04614	Renin-angiotensin system	3/975	23/8144	0.5313	0.8726	0.7536	LNPEP/NLN/PREP	3
KEGG	hsa04964	Proximal tubule bicarbonate reclamation	3/975	23/8144	0.5313	0.8726	0.7536	CA4/PCK1/ATP1B4	3
KEGG	hsa05134	Legionellosis	7/975	57/8144	0.5322	0.8726	0.7536	PYCARD/CXCL1/CR1/ITGAM/TLR4/CXCL3/CASP8	7
KEGG	hsa00520	Amino sugar and nucleotide sugar metabolism	6/975	49/8144	0.5421	0.8771	0.7575	GFPT2/GNPDA1/UAP1/HKDC1/HK2/GMPPB	6
KEGG	hsa04136	Autophagy - other	4/975	32/8144	0.544	0.8771	0.7575	ATG9B/PPP2CA/ULK2/ATG12	4
KEGG	hsa04215	Apoptosis - multiple species	4/975	32/8144	0.544	0.8771	0.7575	BCL2L11/BCL2/BIRC7/CASP8	4
KEGG	hsa05214	Glioma	9/975	75/8144	0.5505	0.8771	0.7575	PTEN/MAPK3/AKT2/RB1/PRKCA/TGFA/PRKCB/PIK3R3/PIK3CB	9
KEGG	hsa00603	Glycosphingolipid biosynthesis - globo and isoglobo series	2/975	15/8144	0.5513	0.8771	0.7575	FUT2/FUT9	2
KEGG	hsa00604	Glycosphingolipid biosynthesis - ganglio series	2/975	15/8144	0.5513	0.8771	0.7575	ST6GALNAC4/ST6GALNAC6	2
KEGG	hsa04979	Cholesterol metabolism	6/975	50/8144	0.5627	0.8863	0.7654	SORT1/APOB/LCAT/SOAT1/ABCB11/LPL	6
KEGG	hsa05110	Vibrio cholerae infection	6/975	50/8144	0.5627	0.8863	0.7654	PRKCA/ADCY3/CFTR/ADCY9/ATP6V1H/ATP6V0A1	6
KEGG	hsa04971	Gastric acid secretion	9/975	76/8144	0.5671	0.8863	0.7654	PLCB1/PLCB3/PRKCA/ADCY3/ATP1B4/CFTR/PRKCB/ADCY9/SLC9A1	9
KEGG	hsa04130	SNARE interactions in vesicular transport	4/975	33/8144	0.5693	0.8863	0.7654	STX1B/STX16/STX2/STX4	4
KEGG	hsa04722	Neurotrophin signaling pathway	14/975	119/8144	0.5707	0.8863	0.7654	SORT1/MAPK3/AKT2/TP73/SH2B2/MAP3K1/MAP2K5/MAPKAPK2/NTRK3/BCL2/PIK3R3/FRS2/MAPK7/PIK3CB	14
KEGG	hsa01232	Nucleotide metabolism	10/975	85/8144	0.5739	0.887	0.766	AMPD2/TK1/GUK1/AK1/AMPD3/ENTPD3/DUT/AK4/TYMP/AK2	10
KEGG	hsa04664	Fc epsilon RI signaling pathway	8/975	68/8144	0.5772	0.8878	0.7667	MAPK3/AKT2/FYN/PRKCA/SYK/PLA2G4B/PIK3R3/PIK3CB	8
KEGG	hsa04913	Ovarian steroidogenesis	6/975	51/8144	0.5829	0.8923	0.7706	ADCY3/ADCY9/PLA2G4B/CYP1A1/CYP11A1/AKR1C3	6
KEGG	hsa00360	Phenylalanine metabolism	2/975	16/8144	0.5874	0.8949	0.7728	ALDH3B1/HPD	2
KEGG	hsa05031	Amphetamine addiction	8/975	69/8144	0.5944	0.9009	0.778	PRKCA/GRIN3B/PPP1CC/CREB1/CREB3L1/CREB5/TH/PRKCB	8
KEGG	hsa04975	Fat digestion and absorption	5/975	43/8144	0.5981	0.9009	0.778	PNLIP/ACAT2/APOB/PLA2G2D/PLA2G12A	5
KEGG	hsa04721	Synaptic vesicle cycle	9/975	78/8144	0.5997	0.9009	0.778	STX1B/SLC17A7/SNAP25/SLC1A2/NAPA/STX2/SYT1/ATP6V1H/ATP6V0A1	9
KEGG	hsa04218	Cellular senescence	18/975	156/8144	0.6043	0.9037	0.7804	NFATC3/PTEN/MAPK3/AKT2/RB1/FOXO1/PPP1CC/NFATC4/MAPKAPK2/HLA-A/RRAS2/SMAD3/ZFP36L1/EIF4EBP1/PIK3R3/TGFB3/CCNB3/PIK3CB	18
KEGG	hsa04072	Phospholipase D signaling pathway	17/975	148/8144	0.6112	0.9098	0.7857	MAPK3/AKT2/FYN/PLCB1/AVPR1A/PLCB3/PRKCA/ADCY3/SYK/ADCY9/RAPGEF3/PLA2G4B/RRAS2/SPHK1/PIK3R3/GRM1/PIK3CB	17
KEGG	hsa00450	Selenocompound metabolism	2/975	17/8144	0.6213	0.9138	0.7892	INMT/MTR	2
KEGG	hsa00600	Sphingolipid metabolism	6/975	53/8144	0.6217	0.9138	0.7892	SMPD2/SMPD3/CERS3/CERS1/SPTLC1/SPHK1	6
KEGG	hsa04213	Longevity regulating pathway - multiple species	7/975	62/8144	0.6246	0.9138	0.7892	AKT2/FOXO1/ADCY3/ADCY9/PIK3R3/IRS4/PIK3CB	7
KEGG	hsa00564	Glycerophospholipid metabolism	11/975	98/8144	0.6375	0.9138	0.7892	LCAT/PEMT/PTDSS1/GPD2/GPD1/PLA2G4B/PLA2G2D/LCLAT1/PLB1/ETNK2/PLA2G12A	11
KEGG	hsa04750	Inflammatory mediator regulation of TRP channels	11/975	98/8144	0.6375	0.9138	0.7892	PLCB1/PLCB3/PRKCA/PPP1CC/ADCY3/PRKCB/ADCY9/PLA2G4B/PIK3R3/PRKCH/PIK3CB	11
KEGG	hsa05231	Choline metabolism in cancer	11/975	98/8144	0.6375	0.9138	0.7892	SLC22A1/MAPK3/AKT2/HIF1A/PRKCA/SLC22A4/PRKCB/PLA2G4B/EIF4EBP1/PIK3R3/PIK3CB	11
KEGG	hsa03460	Fanconi anemia pathway	6/975	54/8144	0.6403	0.9138	0.7892	ERCC4/FANCA/RAD51C/REV1/FAN1/REV3L	6
KEGG	hsa01040	Biosynthesis of unsaturated fatty acids	3/975	27/8144	0.6435	0.9138	0.7892	TECR/FADS2/ELOVL5	3
KEGG	hsa04659	Th17 cell differentiation	12/975	108/8144	0.6537	0.9138	0.7892	NFATC3/MAPK3/HIF1A/IFNG/RUNX1/IL23A/RARA/RXRA/SMAD3/JAK2/AHR/IL23R	12
KEGG	hsa04145	Phagosome	17/975	152/8144	0.6563	0.9138	0.7892	THBS4/COLEC12/ITGAV/ITGAM/CLEC7A/SFTPD/DYNC1I1/HLA-A/ATP6V1H/FCGR2C/FCGR3A/THBS2/TLR4/ATP6V0A1/TUBA3C/NOS1/TUBB4A	17
KEGG	hsa03050	Proteasome	5/975	46/8144	0.6593	0.9138	0.7892	PSMD9/PSMB7/IFNG/PSMA7/POMP	5
KEGG	hsa00562	Inositol phosphate metabolism	8/975	73/8144	0.6595	0.9138	0.7892	IMPA1/PTEN/PLCB1/SYNJ2/PLCB3/SACM1L/PIK3C2G/PIK3CB	8
KEGG	hsa01524	Platinum drug resistance	8/975	73/8144	0.6595	0.9138	0.7892	MAPK3/AKT2/FAS/BCL2/PIK3R3/PIK3CB/CASP8/REV3L	8
KEGG	hsa04115	p53 signaling pathway	8/975	73/8144	0.6595	0.9138	0.7892	PTEN/TP53AIP1/TP73/FAS/BCL2/CCNG1/RCHY1/CASP8	8
KEGG	hsa04146	Peroxisome	9/975	82/8144	0.6609	0.9138	0.7892	IDH2/PEX5L/AMACR/ACOX2/ACSL1/EPHX2/EHHADH/CROT/DHRS4	9
KEGG	hsa00250	Alanine, aspartate and glutamate metabolism	4/975	37/8144	0.662	0.9138	0.7892	GFPT2/ABAT/ASPA/GAD2	4
KEGG	hsa05216	Thyroid cancer	4/975	37/8144	0.662	0.9138	0.7892	MAPK3/TCF7L2/RXRA/TCF7	4
KEGG	hsa05130	Pathogenic Escherichia coli infection	22/975	197/8144	0.6706	0.9218	0.796	MYO1G/PYCARD/MAPK3/CLDN11/TRADD/TNFSF10/FYN/NCK2/CLDN16/SLC9A3R1/CLDN20/TRAF2/FAS/MYO1D/TLR4/RIPK1/CLDN17/TUBA3C/CLDN15/BAIAP2/TUBB4A/CASP8	22
KEGG	hsa05135	Yersinia infection	15/975	137/8144	0.6843	0.9327	0.8055	ITGA4/MEFV/NFATC3/PYCARD/MAPK3/AKT2/CCL2/DOCK1/TRAF2/ARHGEF7/ELMO1/TLR4/PIK3R3/BAIAP2/PIK3CB	15
KEGG	hsa05145	Toxoplasmosis	12/975	112/8144	0.7032	0.9327	0.8055	ITGA6/LAMA4/SOCS1/MAPK3/AKT2/IFNG/BCL2/JAK2/TLR4/TGFB3/BIRC7/CASP8	12
KEGG	hsa05133	Pertussis	8/975	76/8144	0.7041	0.9327	0.8055	PYCARD/MAPK3/NOD1/C4A/ITGAM/C4BPB/IL23A/TLR4	8
KEGG	hsa05212	Pancreatic cancer	8/975	76/8144	0.7041	0.9327	0.8055	MAPK3/AKT2/RB1/TGFA/SMAD3/PIK3R3/TGFB3/PIK3CB	8
KEGG	hsa05162	Measles	15/975	139/8144	0.7059	0.9327	0.8055	AKT2/EIF2AK4/TRADD/TP73/FAS/TRAF3/BCL2/TNFAIP3/TLR4/PIK3R3/OAS1/IFNAR2/RCHY1/PIK3CB/CASP8	15
KEGG	hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	2/975	20/8144	0.71	0.9327	0.8055	CHSY3/XYLT1	2
KEGG	hsa00670	One carbon pool by folate	2/975	20/8144	0.71	0.9327	0.8055	AMT/MTR	2
KEGG	hsa00565	Ether lipid metabolism	5/975	49/8144	0.7141	0.9327	0.8055	GDPD3/PLA2G4B/PLA2G2D/PLB1/PLA2G12A	5
KEGG	hsa04672	Intestinal immune network for IgA production	5/975	49/8144	0.7141	0.9327	0.8055	ITGA4/MAP3K14/CCR10/ICOS/ICOSLG	5
KEGG	hsa05030	Cocaine addiction	5/975	49/8144	0.7141	0.9327	0.8055	GRIN3B/CREB1/CREB3L1/CREB5/TH	5
KEGG	hsa00630	Glyoxylate and dicarboxylate metabolism	3/975	30/8144	0.7142	0.9327	0.8055	ACAT2/AMT/ACSS1	3
KEGG	hsa05169	Epstein-Barr virus infection	22/975	202/8144	0.7161	0.9327	0.8055	AKT2/TRADD/RB1/MAP3K14/TRAF5/ICAM1/BCL2L11/CXCL10/TRAF2/SYK/FAS/ENTPD3/HLA-A/TRAF3/BCL2/TNFAIP3/PIK3R3/OAS1/RIPK1/IFNAR2/PIK3CB/CASP8	22
KEGG	hsa05100	Bacterial invasion of epithelial cells	8/975	77/8144	0.718	0.9327	0.8055	CAV1/DOCK1/CAV3/CBL/ELMO1/PIK3R3/CTNNA2/PIK3CB	8
KEGG	hsa00260	Glycine, serine and threonine metabolism	4/975	40/8144	0.7221	0.9327	0.8055	DMGDH/GATM/PGAM1/AMT	4
KEGG	hsa05415	Diabetic cardiomyopathy	22/975	203/8144	0.7247	0.9327	0.8055	COL1A1/PTEN/AKT2/GFPT2/PLCB1/PDHA2/PLCB3/NDUFS2/PRKCA/AGER/PPP1CC/RYR2/MMP2/PRKCB/SLC2A1/PDK2/SMAD3/PIK3R3/UQCRH/TGFB3/NOS3/PIK3CB	22
KEGG	hsa04330	Notch signaling pathway	6/975	59/8144	0.7248	0.9327	0.8055	RFNG/CTBP2/TLE6/TLE3/HES5/JAG1	6
KEGG	hsa04217	Necroptosis	17/975	159/8144	0.728	0.9331	0.8058	PYCARD/TRADD/TNFSF10/PYGB/TRAF5/IFNG/RNF103-CHMP3/TRAF2/FAS/PLA2G4B/BCL2/TNFAIP3/JAK2/TLR4/RIPK1/IFNAR2/CASP8	17
KEGG	hsa04924	Renin secretion	7/975	69/8144	0.735	0.935	0.8075	PDE3B/PLCB1/ADRB2/PLCB3/CREB1/PRKG2/CLCA1	7
KEGG	hsa04710	Circadian rhythm	3/975	31/8144	0.7353	0.935	0.8075	NPAS2/CREB1/SKP1	3
KEGG	hsa04216	Ferroptosis	4/975	41/8144	0.7402	0.9376	0.8097	HMOX1/MAP1LC3B2/ACSL1/MAP1LC3B	4
KEGG	hsa00130	Ubiquinone and other terpenoid-quinone biosynthesis	1/975	11/8144	0.7543	0.9465	0.8174	HPD	1
KEGG	hsa01240	Biosynthesis of cofactors	16/975	153/8144	0.7557	0.9465	0.8174	UGT2A2/UGT2A3/UGT1A1/KMO/HPD/UGT2A1/UGT2B28/UGT2B10/AK1/AK4/UGT2B15/UGT2B4/GMPPB/UGT1A7/QPRT/AK2	16
KEGG	hsa00220	Arginine biosynthesis	2/975	22/8144	0.7589	0.9465	0.8174	NOS3/NOS1	2
KEGG	hsa00340	Histidine metabolism	2/975	22/8144	0.7589	0.9465	0.8174	ALDH3B1/ASPA	2
KEGG	hsa04613	Neutrophil extracellular trap formation	20/975	190/8144	0.7647	0.95	0.8204	FPR2/MAPK3/AKT2/PLCB1/PLCB3/CR1/ITGAM/PRKCA/AGER/CLEC7A/TLR8/SYK/PRKCB/HDAC11/FCGR3A/TLR4/PIK3R3/GP1BA/FPR1/PIK3CB	20
KEGG	hsa04940	Type I diabetes mellitus	4/975	43/8144	0.7738	0.9576	0.827	IFNG/FAS/HLA-A/GAD2	4
KEGG	hsa00230	Purine metabolism	13/975	128/8144	0.7768	0.9577	0.8271	PDE3B/AMPD2/GUK1/ADCY3/PDE7A/AK1/AMPD3/ADCY9/ENTPD3/AK4/ADCY10/PDE4D/AK2	13
KEGG	hsa00310	Lysine degradation	6/975	63/8144	0.7816	0.9599	0.829	PRDM7/ACAT2/EHHADH/EZH1/ECHS1/DOT1L	6
KEGG	hsa05321	Inflammatory bowel disease	6/975	65/8144	0.8065	0.9867	0.8521	IFNG/IL23A/SMAD3/TLR4/TGFB3/IL23R	6
KEGG	hsa01230	Biosynthesis of amino acids	7/975	75/8144	0.8098	0.987	0.8524	PFKM/IDH2/PC/ALDOB/PGK2/PGAM1/MTR	7
KEGG	hsa05330	Allograft rejection	3/975	38/8144	0.8499	1	0.8636	IFNG/FAS/HLA-A	3
KEGG	hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	2/975	27/8144	0.8511	1	0.8636	FUT2/FUT9	2
KEGG	hsa04966	Collecting duct acid secretion	2/975	27/8144	0.8511	1	0.8636	SLC4A1/ATP6V0A1	2
KEGG	hsa00430	Taurine and hypotaurine metabolism	1/975	16/8144	0.8703	1	0.8636	GAD2	1
KEGG	hsa04530	Tight junction	16/975	169/8144	0.8737	1	0.8636	CLDN11/ACTN1/CLDN16/MAP3K1/SLC9A3R1/F11R/RUNX1/CFTR/CLDN20/IGSF5/CD1A/PPP2CA/CLDN17/TUBA3C/CLDN15/CD1C	16
KEGG	hsa04914	Progesterone-mediated oocyte maturation	9/975	102/8144	0.8759	1	0.8636	CPEB3/MAPK3/AKT2/PDE3B/ADCY3/ADCY9/PIK3R3/CCNB3/PIK3CB	9
KEGG	hsa04744	Phototransduction	2/975	29/8144	0.878	1	0.8636	SAG/GUCA1B	2
KEGG	hsa04120	Ubiquitin mediated proteolysis	13/975	142/8144	0.8828	1	0.8636	SOCS1/SMURF1/UBE2R2/UBE2U/CBL/MAP3K1/CDC20/UBA3/SKP1/WWP2/BIRC7/NHLRC1/RCHY1	13
KEGG	hsa05332	Graft-versus-host disease	3/975	42/8144	0.8937	1	0.8636	IFNG/FAS/HLA-A	3
KEGG	hsa05203	Viral carcinogenesis	19/975	204/8144	0.9057	1	0.8636	MAPK3/TRADD/RB1/ACTN1/TRAF5/CDC20/CREB1/CREB3L1/TRAF2/SYK/CREB5/MAPKAPK2/HLA-A/SCIN/HDAC11/TRAF3/PIK3R3/PIK3CB/CASP8	19
KEGG	hsa01210	2-Oxocarboxylic acid metabolism	1/975	19/8144	0.9116	1	0.8636	IDH2	1
KEGG	hsa03410	Base excision repair	2/975	33/8144	0.9188	1	0.8636	OGG1/SMUG1	2
KEGG	hsa04114	Oocyte meiosis	11/975	131/8144	0.9261	1	0.8636	CPEB3/REC8/MAPK3/FBXO5/PPP1CC/ADCY3/CDC20/ADCY9/STAG3/PPP2CA/SKP1	11
KEGG	hsa00240	Pyrimidine metabolism	4/975	58/8144	0.9288	1	0.8636	TK1/ENTPD3/DUT/TYMP	4
KEGG	hsa04142	Lysosome	11/975	132/8144	0.9302	1	0.8636	SORT1/NCOA7/ACP5/CTSK/CD63/AP1G1/LAMP3/ATP6V1H/CTSC/ATP6V0A1/TPP1	11
KEGG	hsa00900	Terpenoid backbone biosynthesis	1/975	22/8144	0.9397	1	0.8636	ACAT2	1
KEGG	hsa04932	Non-alcoholic fatty liver disease	13/975	155/8144	0.9408	1	0.8636	AKT2/NDUFS2/SREBF1/BCL2L11/TRAF2/FAS/ERN1/RXRA/PIK3R3/UQCRH/LEPR/PIK3CB/CASP8	13
KEGG	hsa00561	Glycerolipid metabolism	4/975	61/8144	0.9447	1	0.8636	PNLIP/GK2/LCLAT1/LPL	4
KEGG	hsa00510	N-Glycan biosynthesis	3/975	50/8144	0.9486	1	0.8636	MGAT3/MGAT4C/MGAT5B	3
KEGG	hsa05340	Primary immunodeficiency	2/975	38/8144	0.9519	1	0.8636	IL7R/ICOS	2
KEGG	hsa03250	Viral life cycle - HIV-1	4/975	63/8144	0.9534	1	0.8636	APOBEC3D/APOBEC3G/NUP153/ELL2	4
KEGG	hsa04623	Cytosolic DNA-sensing pathway	4/975	63/8144	0.9534	1	0.8636	AIM2/PYCARD/CXCL10/RIPK1	4
KEGG	hsa03013	Nucleocytoplasmic transport	8/975	108/8144	0.9553	1	0.8636	NMD3/NUP210L/ALYREF/NUP35/NUP153/IPO5/SUMO3/GLE1	8
KEGG	hsa00513	Various types of N-glycan biosynthesis	2/975	39/8144	0.9567	1	0.8636	CHST9/MGAT4C	2
KEGG	hsa05320	Autoimmune thyroid disease	3/975	53/8144	0.9613	1	0.8636	CTLA4/FAS/HLA-A	3
KEGG	hsa05202	Transcriptional misregulation in cancer	16/975	193/8144	0.9616	1	0.8636	ELK4/COMMD3-BMI1/FOXO1/ZBTB16/DEFA1/MITF/ITGAM/ETV6/RUNX1T1/MMP3/RUNX1/RARA/RXRA/WT1/NR4A3/DOT1L	16
KEGG	hsa00563	Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	1/975	26/8144	0.9639	1	0.8636	PIGV	1
KEGG	hsa04950	Maturity onset diabetes of the young	1/975	26/8144	0.9639	1	0.8636	MAFA	1
KEGG	hsa03440	Homologous recombination	2/975	41/8144	0.965	1	0.8636	RAD51C/XRCC3	2
KEGG	hsa05016	Huntington disease	27/975	306/8144	0.9697	1	0.8636	AMBRA1/GPX3/SLC1A2/PLCB1/PSMD9/PLCB3/PSMB7/DNAI1/NDUFS2/ULK1/HIP1/DCTN2/CREB1/PSMA7/PPARGC1A/CREB3L1/TRAF2/CREB5/ERN1/DNAH14/ULK2/UQCRH/TUBA3C/TUBB4A/KIF5A/DNAH9/CASP8	27
KEGG	hsa05014	Amyotrophic lateral sclerosis	33/975	364/8144	0.9701	1	0.8636	AMBRA1/NUP210L/GPX3/ALYREF/MAP1LC3B2/SLC1A2/PSMD9/PFN4/PSMB7/DNAI1/NRG1/NDUFS2/DERL1/ULK1/DCTN2/TNFRSF1B/PSMA7/TRAF2/ATXN2/MAP1LC3B/ERN1/BCL2/DNAH14/ULK2/NUP35/UQCRH/NUP153/TUBA3C/NOS1/TUBB4A/KIF5A/DNAH9/GLE1	33
KEGG	hsa00480	Glutathione metabolism	3/975	58/8144	0.9761	1	0.8636	GPX3/IDH2/ODC1	3
KEGG	hsa03022	Basal transcription factors	2/975	45/8144	0.9773	1	0.8636	TAF5/TAF12	2
KEGG	hsa05020	Prion disease	23/975	273/8144	0.9775	1	0.8636	C8A/C8B/CAV1/MAPK3/FYN/PSMD9/EGR1/PSMB7/NDUFS2/CAV3/GRIN3B/NCAM2/CREB1/RYR2/PSMA7/CREB3L1/CREB5/PIK3R3/UQCRH/TUBA3C/TUBB4A/KIF5A/PIK3CB	23
KEGG	hsa03015	mRNA surveillance pathway	6/975	97/8144	0.9808	1	0.8636	ALYREF/PPP1CC/SMG5/PPP2CA/PPP2R3A/GLE1	6
KEGG	hsa05034	Alcoholism	14/975	187/8144	0.9835	1	0.8636	SLC29A1/MAPK3/GNG2/GNG7/GRIN3B/PPP1CC/CREB1/CREB3L1/GNG10/CREB5/TH/CRH/HDAC11/GNG3	14
KEGG	hsa05022	Pathways of neurodegeneration - multiple diseases	43/975	476/8144	0.9851	1	0.8636	AMBRA1/WNT10B/GPX3/MAPK3/MAP1LC3B2/AXIN2/PLCB1/PSMD9/PLCB3/PSMB7/DNAI1/NDUFS2/FZD10/DERL1/PRKCA/ULK1/HIP1/DCTN2/AGER/WNT3/TNFRSF1B/RYR2/PSMA7/TRAF2/ATXN2/PRKCB/LRP5/FAS/MAP1LC3B/ERN1/BCL2/DNAH14/MAPT/ULK2/UQCRH/TUBA3C/NOS1/GRM1/FZD8/TUBB4A/KIF5A/DNAH9/CASP8	43
KEGG	hsa04144	Endocytosis	20/975	251/8144	0.9853	1	0.8636	RAB31/RAB11FIP5/GRK5/EHD4/ARRB1/CAV1/STAM2/SMURF1/CAPZB/SH3GL1/DAB2/CAV3/CBL/RNF103-CHMP3/HLA-A/SMAD3/SH3GLB2/RAB11FIP2/FGFR2/KIF5A	20
KEGG	hsa05171	Coronavirus disease - COVID-19	18/975	232/8144	0.9865	1	0.8636	HBEGF/C8A/C8B/MAPK3/CCL2/C4A/PRKCA/MMP3/CXCL10/TLR8/SYK/PRKCB/TRAF3/TLR4/PIK3R3/OAS1/IFNAR2/PIK3CB	18
KEGG	hsa03020	RNA polymerase	1/975	34/8144	0.987	1	0.8636	POLR1A	1
KEGG	hsa05010	Alzheimer disease	33/975	384/8144	0.9878	1	0.8636	AMBRA1/WNT10B/MAPK3/AKT2/AXIN2/PLCB1/PSMD9/PLCB3/PSMB7/NDUFS2/FZD10/ULK1/AGER/WNT3/SLC39A11/PSMA7/TRAF2/LRP5/FAS/ERN1/MAPT/ULK2/PIK3R3/UQCRH/TUBA3C/NOS1/FZD8/LPL/TUBB4A/IRS4/KIF5A/PIK3CB/CASP8	33
KEGG	hsa04612	Antigen processing and presentation	4/975	78/8144	0.9879	1	0.8636	IFNG/CREB1/HLA-A/KLRC2	4
KEGG	hsa04110	Cell cycle	8/975	126/8144	0.9879	1	0.8636	BUB3/RB1/CDKN1C/CDC20/SMAD3/SKP1/TGFB3/CCNB3	8
KEGG	hsa00270	Cysteine and methionine metabolism	2/975	51/8144	0.9883	1	0.8636	AHCYL1/MTR	2
KEGG	hsa03018	RNA degradation	4/975	79/8144	0.989	1	0.8636	PFKM/LSM7/BTG3/XRN1	4
KEGG	hsa04658	Th1 and Th2 cell differentiation	5/975	92/8144	0.9894	1	0.8636	NFATC3/MAPK3/IFNG/JAK2/JAG1	5
KEGG	hsa00760	Nicotinate and nicotinamide metabolism	1/975	36/8144	0.99	1	0.8636	QPRT	1
KEGG	hsa05208	Chemical carcinogenesis - reactive oxygen species	16/975	223/8144	0.9935	1	0.8636	HMOX1/PTEN/MAPK3/AKT2/HIF1A/CYP2F1/NDUFS2/MAP3K14/EPHX2/EPHX4/CYP1A1/PIK3R3/UQCRH/AHR/PIK3CB/AKR1C3	16
KEGG	hsa04141	Protein processing in endoplasmic reticulum	11/975	171/8144	0.9947	1	0.8636	SEC31B/EIF2AK4/UBXN8/DERL1/TRAM1L1/BAG2/TRAF2/ERN1/BCL2/DERL3/SKP1	11
KEGG	hsa04714	Thermogenesis	16/975	232/8144	0.9964	1	0.8636	KDM3B/NDUFS2/ACSL1/ADCY3/CREB1/KLB/PPARGC1A/CREB3L1/PRKG2/PLIN1/CREB5/ADCY9/ADCY10/ACTL6A/FRS2/UQCRH	16
KEGG	hsa03420	Nucleotide excision repair	1/975	47/8144	0.9975	1	0.8636	ERCC4	1
KEGG	hsa05322	Systemic lupus erythematosus	6/975	136/8144	0.9994	1	0.8636	C8A/C8B/ACTN1/C4A/IFNG/FCGR3A	6
KEGG	hsa03008	Ribosome biogenesis in eukaryotes	4/975	109/8144	0.9994	1	0.8636	NMD3/REXO1/RMRP/XRN1	4
KEGG	hsa00190	Oxidative phosphorylation	5/975	134/8144	0.9998	1	0.8636	NDUFS2/PPA1/ATP6V1H/UQCRH/ATP6V0A1	5
KEGG	hsa05168	Herpes simplex virus 1 infection	34/975	495/8144	1	1	0.8636	ALYREF/ZNF154/AKT2/EIF2AK4/TRADD/CCL2/TRAF5/ZNF836/PPP1CC/IFNG/TRAF2/ZNF99/SYK/FAS/HLA-A/ZNF304/ZNF98/TRAF3/BCL2/ZNF195/ZFP28/ZNF177/JAK2/EIF4EBP1/ZNF20/PIK3R3/OAS1/IFNAR2/ZNF620/ZNF676/ZNF611/ZNF334/PIK3CB/CASP8	34
KEGG	hsa05012	Parkinson disease	12/975	266/8144	1	1	0.8636	PSMD9/PSMB7/NDUFS2/SLC39A11/PSMA7/TH/ERN1/MAPT/UQCRH/TUBA3C/TUBB4A/KIF5A	12
KEGG	hsa03040	Spliceosome	3/975	147/8144	1	1	0.8636	ALYREF/LSM7/TCERG1	3
KEGG	hsa03010	Ribosome	2/975	158/8144	1	1	0.8636	MRPS9/MRPL35	2