ONTOLOGY	ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	qvalue	geneID	Count
BP	GO:0043087	regulation of GTPase activity	90/1884	479/18670	4.076e-09	2.417e-05	2.325e-05	PLEKHG4/ARHGEF16/ARHGAP15/FAM13A/CCL26/ITGB1BP1/ALS2CL/PLCB1/SIPA1L1/AGAP11/IQSEC1/ARHGAP1/ERRFI1/RIC8B/RGS10/ITGA6/RASA3/SGSM2/ACAP3/RASGRP3/PYCARD/BCR/ARHGEF10L/SYNGAP1/STXBP5L/AGAP1/FGD5/CDC42EP2/SRGAP3/ARHGAP31/ARHGAP5/RANBP3/SRGAP1/PTK2/ARHGEF7/TNK2/DLC1/ARHGEF12/GPS2/RINL/PLXNC1/RGPD3/RGP1/ARHGAP32/ARHGAP20/ASAP2/DOCK4/MYO9B/EPHA3/CHML/ARHGAP22/PLXNB2/ARHGAP36/RAPGEF6/ASAP3/ARRB2/TBCD/ARHGAP35/ECT2/RASAL2/STARD13/TAX1BP3/RAPGEF1/TBC1D22A/THY1/RAPGEF3/TBC1D30/RAP1GAP/VAV2/IQGAP2/ARRB1/DOCK5/NTRK3/TSC2/RGS11/DOCK10/TBC1D2/AMOT/DYNLT1/PLXNA2/RASAL3/ARHGAP27/PLXND1/RTN4R/AGFG1/ARFGAP1/FOXJ1/FGD2/RCC2/NTF3	90
BP	GO:0051056	regulation of small GTPase mediated signal transduction	69/1884	338/18670	8.853e-09	2.625e-05	2.524e-05	RHOJ/PLEKHG4/ARHGEF16/ARHGAP15/TIMP2/FAM13A/KANK2/SIPA1L1/SYNPO2L/IQSEC1/ARHGAP1/MMD2/TNK1/RHOBTB2/EPS8L3/RASA3/PSD2/MADD/BCR/ECT2L/PDGFRB/ARHGEF10L/DEPDC7/SYNGAP1/CSF1/FGD5/RHOQ/SH2B2/SRGAP3/ARHGAP31/ARHGEF3/ARHGAP5/SRGAP1/F2RL3/ARHGEF7/SCAI/DLC1/ARHGEF12/ITGA3/SPRY4/A2M/ARHGAP32/ARHGAP20/TRIO/MYO9B/DNMBP/CBL/ARHGAP22/ARHGEF25/ARHGAP36/AKAP13/ARHGAP35/APOC3/ECT2/STARD13/RAPGEF1/RAP1GAP/CD2AP/DENND4B/VAV2/ARRB1/TSC2/AMOT/DYNLT1/RASAL3/CDC42/RTN4R/ARFGAP1/FGD2	69
BP	GO:0043062	extracellular structure organization	77/1884	422/18670	1.889e-07	0.0003734	0.0003591	TNXB/MMP14/ITGA9/TIMP2/LUM/ADAMTSL2/NID1/ADAMTS4/ITGA6/FOXF2/COL4A2/ICAM2/CTRB1/COL13A1/LOXL2/VIT/RAMP2/COL4A1/CAPN2/DCN/LIPG/PHLDB1/APOA5/PTK2/COL9A1/ITGA3/P4HA1/ST7/A2M/ELANE/SH3PXD2B/ELF3/COL7A1/DGAT1/LCAT/COL1A1/WT1/MFAP4/FURIN/CD34/VWF/ITGB2/PECAM1/LAMA4/SPP1/APOC1/GAS2/COL15A1/PDCD6IP/COL5A2/APOC3/TGFBR1/KLK2/COL4A5/LAMA3/ITGA7/POSTN/CRISPLD2/PLAGL2/MMP19/ADAMTS2/FBLN1/PRKACA/FLRT2/STAM/HSPG2/ICAM3/DPP4/HTRA1/SERPINB5/COL14A1/TNFRSF1A/SMPD3/ARF1/MYF5/ITGB5/SPOCK2	77
BP	GO:0043547	positive regulation of GTPase activity	73/1884	405/18670	6.34e-07	0.0009216	0.0008863	PLEKHG4/ARHGEF16/ARHGAP15/FAM13A/CCL26/ALS2CL/PLCB1/SIPA1L1/AGAP11/IQSEC1/ARHGAP1/ERRFI1/RIC8B/RGS10/ITGA6/RASA3/SGSM2/ACAP3/RASGRP3/BCR/ARHGEF10L/SYNGAP1/STXBP5L/AGAP1/CDC42EP2/SRGAP3/ARHGAP31/ARHGAP5/RANBP3/SRGAP1/ARHGEF7/DLC1/ARHGEF12/RINL/RGPD3/RGP1/ARHGAP32/ARHGAP20/ASAP2/DOCK4/MYO9B/CHML/ARHGAP22/ARHGAP36/RAPGEF6/ASAP3/TBCD/ARHGAP35/ECT2/RASAL2/STARD13/TAX1BP3/RAPGEF1/TBC1D22A/THY1/RAPGEF3/TBC1D30/RAP1GAP/ARRB1/DOCK5/NTRK3/TSC2/RGS11/DOCK10/TBC1D2/RASAL3/ARHGAP27/RTN4R/AGFG1/ARFGAP1/FOXJ1/RCC2/NTF3	73
BP	GO:0007266	Rho protein signal transduction	44/1884	203/18670	7.77e-07	0.0009216	0.0008863	RHOJ/PLEKHG4/ARHGEF16/KANK2/SYNPO2L/ARHGAP1/RHOBTB2/EPS8L3/BCR/ECT2L/PDGFRB/ARHGEF10L/FGD5/RHOQ/CDC42EP2/ARHGEF3/ARHGAP5/F2RL3/ARHGEF7/SCAI/DLC1/ARHGEF12/ITGA3/C15orf62/SYNJ2BP/TRIO/MYO9B/DNMBP/ARHGEF25/PECAM1/AKAP13/ROCK1/ARHGAP35/APOC3/ECT2/TAX1BP3/VAV2/CDC42EP5/ARRB1/RHOBTB3/WAS/CDC42/RTN4R/FGD2	44
BP	GO:0007265	Ras protein signal transduction	77/1884	448/18670	2.122e-06	0.002097	0.002017	RHOJ/PLEKHG4/RAB31/ARHGEF16/TIMP2/KANK2/SYNPO2L/IQSEC1/ARHGAP1/MMD2/TNK1/RHOBTB2/EPS8L3/RASA3/RASGRP3/PSD2/MADD/CDKN1A/BCR/ECT2L/PDGFRB/ARHGEF10L/SYNGAP1/CSF1/FGD5/RRAS2/RHOQ/CDC42EP2/SH2B2/RAP2B/ARHGEF3/ARHGAP5/RAB32/F2RL3/ARHGEF7/SCAI/DLC1/ARHGEF12/ITGA3/SPRY4/C15orf62/SYNJ2BP/TRIO/MYO9B/RAB33B/DNMBP/DOK3/CBL/ARHGEF25/RAB12/PECAM1/RAPGEF6/AKAP13/ROCK1/ARHGAP35/APOC3/ECT2/LAT/TAX1BP3/RAPGEF1/RAPGEF3/PRKD1/DENND4B/VAV2/CDC42EP5/ARRB1/RHOBTB3/DYNLT1/RAB6C/RASAL3/WASF1/WAS/CDC42/WASF2/RTN4R/ARFGAP1/FGD2	77
BP	GO:0022604	regulation of cell morphogenesis	81/1884	484/18670	3.384e-06	0.002867	0.002757	RHOJ/ZSWIM5/LIMD1/WNT3/ARHGAP15/ITGB1BP1/TRAK2/SIPA1L1/TRIM46/FBXO31/ZSWIM6/ARPC2/UNC13D/FMNL2/FMNL3/SYNGAP1/FGD5/TNIK/RHOQ/CDC42EP2/RUFY3/SLC9A3R1/LARP4/PTK2/ARHGEF7/SLITRK1/NIN/DLC1/CPNE5/CUX1/SEMA3D/ZMYM6/SKIL/BAIAP2/FEZF2/PLXNC1/MAP6/C15orf62/RET/FYN/XK/DNMBP/ZNF135/SMURF1/PLXNB2/ITGB2/SPP1/GAS2/SEMA4C/ARHGAP35/MAP2/ITPKA/SEMA3G/ITGA7/TRAK1/POSTN/THY1/CDC42EP5/FBLN1/CSF1R/FBLIM1/DOCK5/PDLIM5/NTRK3/RIMS2/SS18L2/RHOBTB3/SYT4/CFDP1/PLXNA2/UNC13A/CACNG7/ACTN4/DCC/CDC42/PLXND1/RTN4R/PAK3/CAMSAP1/FGD2/RCC2	81
BP	GO:0030198	extracellular matrix organization	65/1884	368/18670	5.177e-06	0.003837	0.00369	TNXB/MMP14/ITGA9/TIMP2/LUM/ADAMTSL2/NID1/ADAMTS4/ITGA6/FOXF2/COL4A2/ICAM2/CTRB1/COL13A1/LOXL2/VIT/RAMP2/COL4A1/CAPN2/DCN/PHLDB1/PTK2/COL9A1/ITGA3/P4HA1/ST7/A2M/ELANE/SH3PXD2B/ELF3/COL7A1/COL1A1/WT1/MFAP4/FURIN/VWF/ITGB2/PECAM1/LAMA4/SPP1/GAS2/COL15A1/COL5A2/TGFBR1/KLK2/COL4A5/LAMA3/ITGA7/POSTN/CRISPLD2/MMP19/ADAMTS2/FBLN1/FLRT2/HSPG2/ICAM3/DPP4/HTRA1/SERPINB5/COL14A1/TNFRSF1A/SMPD3/MYF5/ITGB5/SPOCK2	65
BP	GO:0046578	regulation of Ras protein signal transduction	46/1884	238/18670	1.169e-05	0.007702	0.007408	PLEKHG4/ARHGEF16/TIMP2/KANK2/SYNPO2L/IQSEC1/MMD2/TNK1/EPS8L3/RASA3/PSD2/MADD/BCR/ECT2L/PDGFRB/ARHGEF10L/SYNGAP1/CSF1/FGD5/SH2B2/ARHGEF3/F2RL3/ARHGEF7/SCAI/DLC1/ARHGEF12/ITGA3/SPRY4/TRIO/MYO9B/DNMBP/CBL/ARHGEF25/AKAP13/ARHGAP35/APOC3/ECT2/RAPGEF1/DENND4B/VAV2/ARRB1/DYNLT1/RASAL3/RTN4R/ARFGAP1/FGD2	46
BP	GO:0046777	protein autophosphorylation	45/1884	235/18670	1.848e-05	0.01051	0.01011	NEK10/FGFR3/CAV1/ADIPOQ/TNK1/ERRFI1/VRK2/FER/BCR/PDGFRB/CAMK2A/DAPK2/TNIK/AKT1/RIPK1/LCK/ALK/TYRO3/RAP2B/PTK2/TNK2/GRK5/CSNK1G2/FYN/MAPKAPK3/MAPK3/CLK1/BMX/ITK/STK17B/THY1/PRKD1/PPP2R5C/CSF1R/PRKACA/ERN1/TOM1L1/GPNMB/PIM1/EIF2AK1/FLT3/TAF1/PTK6/MELK/WNK2	45
BP	GO:0031346	positive regulation of cell projection organization	65/1884	383/18670	1.95e-05	0.01051	0.01011	WNT3/P2RX7/SCN1B/FBXO31/ARPC2/EPS8L3/ITGA6/LRRC7/NPTN/RHOQ/CDC42EP2/RUFY3/CREB3L2/ALK/NCKIPSD/ARHGEF7/SLITRK1/NIN/CPNE5/ITGA3/CUX1/SKIL/BAIAP2/PLXNC1/MAP6/C15orf62/RET/FYN/EPHA3/SMURF1/PLXNB2/MIR200C/ARHGAP35/TGFBR1/ITPKA/TRAK1/CAMK1/RAPGEF1/MSTN/ZMYND10/PRKD1/WRAP73/NAV3/CDC42EP5/NDRG4/S100A9/APBB1/NTRK3/RIMS2/SS18L2/PLEKHM1/DYNLT1/SYT4/PLXNA2/UNC13A/CACNG7/CDC42/WASF2/PTK6/PLXND1/ARF1/PAK3/ZMYND8/MOB2/FZD1	65
BP	GO:0032956	regulation of actin cytoskeleton organization	59/1884	343/18670	3.107e-05	0.01535	0.01477	RHOJ/TMOD4/BIN1/CCL26/ITGB1BP1/SYNPO2L/NCK2/SLC9A1/RHOBTB2/ARPC2/FER/PYCARD/PDGFRB/ARHGEF10L/RHOQ/CDC42EP2/FCHSD2/SPTBN5/DLC1/SH3PXD2B/BAIAP2/TMOD3/C15orf62/PTGER4/CDK10/EPHA3/CAV3/CORO2B/PIK3R1/BAIAP2L2/PPFIA1/ASAP3/AKAP13/ROCK1/ARHGAP35/ECT2/FHOD3/TGFBR1/VILL/RAPGEF3/FMN2/CD2AP/CDC42EP5/CSF1R/IQGAP2/NTRK3/RHOBTB3/WHAMMP3/PROX1/CAPZA3/WASF1/WAS/CDC42/LMOD3/WASF2/ARF1/PICK1/PAK3/NTF3	59
BP	GO:0045123	cellular extravasation	17/1884	61/18670	7.671e-05	0.03499	0.03365	AGER/PLCB1/FER/SELPLG/BCR/ELANE/PTGER4/PIK3CG/SIRPA/PLVAP/IL27RA/ITGB2/PECAM1/ROCK1/THY1/LEP/CD177	17
BP	GO:0045666	positive regulation of neuron differentiation	61/1884	371/18670	8.883e-05	0.03694	0.03552	WNT3/TIMP2/SCN1B/MMD2/FBXO31/ITGA6/LRRC7/NPTN/RNF112/RUFY3/CREB3L2/ALK/NCKIPSD/SLITRK1/NIN/CPNE5/ITGA3/CUX1/SKIL/BAIAP2/FEZF2/PLXNC1/NBL1/GDF7/MAP6/RET/FYN/EPHA3/SMURF1/PLXNB2/MIR200C/ARHGAP35/ECT2/ITPKA/TRAK1/CAMK1/RAPGEF1/PRKD1/EIF4G1/NEUROD1/NDRG4/S100A9/APBB1/NTRK3/RIMS2/SS18L2/PROX1/GPRC5B/DYNLT1/SYT4/PLXNA2/UNC13A/CACNG7/SOCS2/PTK6/PLXND1/ARF1/PAK3/ZMYND8/MOB2/FZD1	61
BP	GO:0010976	positive regulation of neuron projection development	49/1884	281/18670	9.966e-05	0.03694	0.03552	WNT3/SCN1B/FBXO31/ITGA6/LRRC7/NPTN/RUFY3/CREB3L2/ALK/NCKIPSD/SLITRK1/NIN/CPNE5/ITGA3/CUX1/SKIL/BAIAP2/PLXNC1/MAP6/RET/FYN/EPHA3/SMURF1/PLXNB2/MIR200C/ARHGAP35/ITPKA/TRAK1/CAMK1/RAPGEF1/PRKD1/NDRG4/S100A9/APBB1/NTRK3/RIMS2/SS18L2/DYNLT1/SYT4/PLXNA2/UNC13A/CACNG7/PTK6/PLXND1/ARF1/PAK3/ZMYND8/MOB2/FZD1	49
BP	GO:0030100	regulation of endocytosis	49/1884	281/18670	9.966e-05	0.03694	0.03552	RAB31/BIN1/SH3GL1/MFGE8/CAV1/ADIPOQ/PYCARD/DAB2/PPARG/SNX33/BCR/APOA5/EHD4/MCTP1/TNK2/MIR185/SYNJ2BP/ANGPT1/SIRPA/LGALS3/EPHA3/CAV3/HIP1/CBL/ATXN2/APOC1/ARRB2/ROCK1/APOC3/LRRTM1/RAPGEF1/ATG5/PRKD1/CD2AP/ARRB1/PIK3CB/PPT1/TSC2/SYT4/EGF/SFTPD/ANKRD13B/ACTN4/SCAMP5/ARF1/PICK1/ARFGAP1/CD177/NTF3	49
BP	GO:0035023	regulation of Rho protein signal transduction	29/1884	140/18670	0.0001317	0.04595	0.04419	PLEKHG4/ARHGEF16/KANK2/SYNPO2L/EPS8L3/BCR/ECT2L/PDGFRB/ARHGEF10L/FGD5/ARHGEF3/F2RL3/ARHGEF7/SCAI/DLC1/ARHGEF12/ITGA3/TRIO/MYO9B/DNMBP/ARHGEF25/AKAP13/ARHGAP35/APOC3/ECT2/VAV2/ARRB1/RTN4R/FGD2	29
BP	GO:0032970	regulation of actin filament-based process	62/1884	388/18670	0.0001778	0.05858	0.05634	RHOJ/TMOD4/TNNC1/BIN1/CCL26/ITGB1BP1/CAV1/SYNPO2L/NCK2/SLC9A1/RHOBTB2/ARPC2/ATP2A2/FER/PYCARD/PDGFRB/ARHGEF10L/RHOQ/CDC42EP2/FCHSD2/SPTBN5/DLC1/SH3PXD2B/BAIAP2/TMOD3/C15orf62/PTGER4/CDK10/EPHA3/CAV3/CORO2B/PIK3R1/BAIAP2L2/PPFIA1/ASAP3/AKAP13/ROCK1/ARHGAP35/ECT2/FHOD3/TGFBR1/VILL/RAPGEF3/FMN2/CD2AP/CDC42EP5/CSF1R/IQGAP2/NTRK3/RHOBTB3/WHAMMP3/PROX1/CAPZA3/WASF1/WAS/CDC42/LMOD3/WASF2/ARF1/PICK1/PAK3/NTF3	62
BP	GO:0008360	regulation of cell shape	30/1884	150/18670	0.0001963	0.06126	0.05892	RHOJ/LIMD1/ARHGAP15/FMNL2/FMNL3/FGD5/RHOQ/CDC42EP2/SLC9A3R1/PTK2/DLC1/BAIAP2/PLXNC1/C15orf62/FYN/DNMBP/PLXNB2/ITGB2/GAS2/ARHGAP35/ITGA7/CDC42EP5/CSF1R/FBLIM1/RHOBTB3/CFDP1/PLXNA2/CDC42/PLXND1/FGD2	30
BP	GO:0007015	actin filament organization	63/1884	400/18670	0.0002385	0.0689	0.06627	RHOJ/TMOD4/BIN1/CCL26/ITGB1BP1/SYNPO2L/NCK2/SLC9A1/RHOBTB2/ARPC2/CAP2/FER/PYCARD/ARHGEF10L/MYO1B/RHOQ/CDC42EP2/RUFY3/FCHSD2/CORO7/SPTBN5/ACTN1/DLC1/SH3PXD2B/BAIAP2/TMOD3/C15orf62/PTGER4/CAV3/CORO2B/HIP1/PIK3R1/BAIAP2L2/PPFIA1/MARCKS/ASAP3/ROCK1/ARHGAP35/FHOD3/TGFBR1/VILL/RAPGEF3/CAP1/FMN2/CD2AP/CDC42EP5/IQGAP2/ARRB1/RHOBTB3/WHAMMP3/PROX1/CAPZA3/XIRP1/WASF1/ACTN4/WAS/CDC42/LMOD3/WASF2/ARF1/PICK1/PAK3/ITGB5	63
BP	GO:0110053	regulation of actin filament organization	45/1884	261/18670	0.000244	0.0689	0.06627	TMOD4/BIN1/CCL26/ITGB1BP1/SYNPO2L/NCK2/SLC9A1/RHOBTB2/ARPC2/FER/PYCARD/ARHGEF10L/CDC42EP2/FCHSD2/SPTBN5/DLC1/SH3PXD2B/BAIAP2/TMOD3/C15orf62/PTGER4/CORO2B/PIK3R1/BAIAP2L2/PPFIA1/ASAP3/ROCK1/ARHGAP35/FHOD3/TGFBR1/VILL/RAPGEF3/FMN2/CDC42EP5/IQGAP2/WHAMMP3/CAPZA3/WASF1/WAS/CDC42/LMOD3/WASF2/ARF1/PICK1/PAK3	45
BP	GO:0031670	cellular response to nutrient	18/1884	74/18670	0.000316	0.08518	0.08192	P2RX7/KANK2/HMOX1/PPARG/P2RY2/BAIAP2/PDK2/FYN/COL1A1/FOLR1/POSTN/TNKS/LEP/P2RX3/VDR/RYR3/PIM1/TAF1	18
BP	GO:0001935	endothelial cell proliferation	35/1884	191/18670	0.0003603	0.09289	0.08934	MIR193A/MMP14/CCL26/ITGB1BP1/CAV1/HMOX1/ECM1/AKT3/LOXL2/PPARG/DLL4/AKT1/STAT5A/SYNJ2BP/THBS4/PRL/CCR3/GDF2/CD34/MIR497/NRARP/PGF/MIRLET7B/TGFBR1/PLCG1/PRKD1/LEP/BMPER/PIK3CB/ERN1/NR4A1/PROX1/MIR329-1/GJA1/SCG2	35
BP	GO:0110020	regulation of actomyosin structure organization	21/1884	95/18670	0.0004286	0.1059	0.1019	ITGB1BP1/SYNPO2L/SLC9A1/ARHGEF10L/DLC1/SH3PXD2B/PTGER4/CAV3/CORO2B/PIK3R1/PPFIA1/ASAP3/AKAP13/ROCK1/ECT2/TGFBR1/RAPGEF3/PROX1/WAS/CDC42/WASF2	21
BP	GO:0006898	receptor-mediated endocytosis	51/1884	316/18670	0.0005052	0.1198	0.1152	RAB31/CAV1/APOL1/PIP5K1C/SAG/DAB2/RAMP2/CD9/APOA5/FCHSD2/TNK2/FCGR1B/MIR185/HBA2/ANGPT1/SNAP25/CAV3/HIP1/CBL/AP2A2/FOLR1/ATXN2/ITGB2/APOC1/ARRB2/APOC3/AP1S1/LRRTM1/ARR3/CAP1/CD2AP/IGF2R/ARRB1/PIK3CB/PPT1/HSPG2/CUBN/EGF/KIAA1107/SFTPD/ANKRD13B/CACNG7/WASF1/CLTC/GRIA1/SLC9B2/ARHGAP27/ARF1/PICK1/COLEC12/NTF3	51
BP	GO:0010769	regulation of cell morphogenesis involved in differentiation	49/1884	301/18670	0.0005279	0.1204	0.1158	ZSWIM5/WNT3/ITGB1BP1/TRAK2/SIPA1L1/TRIM46/FBXO31/ZSWIM6/ARPC2/UNC13D/SYNGAP1/TNIK/RUFY3/PTK2/ARHGEF7/SLITRK1/NIN/CUX1/SEMA3D/SKIL/BAIAP2/FEZF2/PLXNC1/MAP6/RET/XK/PLXNB2/SPP1/SEMA4C/ARHGAP35/MAP2/ITPKA/SEMA3G/TRAK1/POSTN/THY1/FBLN1/DOCK5/PDLIM5/NTRK3/SS18L2/PLXNA2/ACTN4/DCC/CDC42/PLXND1/RTN4R/PAK3/RCC2	49
BP	GO:1902903	regulation of supramolecular fiber organization	55/1884	352/18670	0.0006969	0.1531	0.1472	TMOD4/BIN1/CCL26/ITGB1BP1/SYNPO2L/NCK2/SLC9A1/SLAIN2/RHOBTB2/ARPC2/FER/PYCARD/ARHGEF10L/CDC42EP2/FCHSD2/SPTBN5/NIN/DLC1/SH3PXD2B/BAIAP2/TMOD3/C15orf62/PTGER4/CAV3/CORO2B/PIK3R1/BAIAP2L2/PPFIA1/ASAP3/AKAP13/ROCK1/MAP6D1/TBCD/ARHGAP35/MAP2/FHOD3/TGFBR1/VILL/RAPGEF3/NAV3/FMN2/CDC42EP5/IQGAP2/WHAMMP3/PROX1/CAPZA3/WASF1/WAS/CDC42/LMOD3/WASF2/ARF1/PICK1/PAK3/CAMSAP1	55
BP	GO:0010975	regulation of neuron projection development	73/1884	499/18670	0.0007486	0.1562	0.1502	ZSWIM5/WNT3/TRAK2/SIPA1L1/SCN1B/TRIM46/FBXO31/ZSWIM6/ITGA6/LRRC7/ACAP3/NPTN/SYNGAP1/TNIK/RUFY3/AKT1/CREB3L2/ALK/PTPRF/RTN4IP1/NCKIPSD/PTK2/SLITRK1/NIN/CPNE5/ITGA3/CUX1/SEMA3D/SKIL/BAIAP2/FEZF2/PLXNC1/MAP6/RET/FYN/XK/EPHA3/SNAP25/SMURF1/PLXNB2/MIR200C/SPP1/SEMA4C/ARHGAP35/MAP2/ITPKA/SEMA3G/TRAK1/CAMK1/RAPGEF1/THY1/PRKD1/NDRG4/S100A9/APBB1/PDLIM5/NTRK3/RIMS2/SS18L2/DYNLT1/SYT4/PLXNA2/UNC13A/CACNG7/DCC/PTK6/PLXND1/ARF1/RTN4R/PAK3/ZMYND8/MOB2/FZD1	73
BP	GO:0030838	positive regulation of actin filament polymerization	21/1884	99/18670	0.000764	0.1562	0.1502	BIN1/CCL26/NCK2/RHOBTB2/ARPC2/FER/PYCARD/CDC42EP2/FCHSD2/BAIAP2/C15orf62/BAIAP2L2/FMN2/CDC42EP5/IQGAP2/WHAMMP3/WASF1/WAS/LMOD3/ARF1/PICK1	21
BP	GO:0071496	cellular response to external stimulus	53/1884	339/18670	0.0008507	0.1681	0.1617	PIEZO1/DAPL1/P2RX7/KANK2/HMOX1/SLC9A1/MAP1LC3B2/ITGA6/COMT/PPARG/CDKN1A/AVPR1A/TNFSF14/P2RY2/MYH13/AKT1/CBS/SLC2A1/BAIAP2/RRAGA/PTGER4/TLR8/PDK2/MAP3K14/FYN/COL1A1/AMBRA1/CBL/FOLR1/MAPK3/ARHGAP35/POSTN/ATG5/PRKD1/TNKS/LEP/EIF4G1/P2RX3/FOS/MAP3K1/HIGD1A/VDR/NPPA/RYR3/PIM1/GAS2L1/TAF1/GJA1/TNFRSF1A/AKR1C3/WIPI2/KLF10/PICK1	53
BP	GO:0045806	negative regulation of endocytosis	16/1884	68/18670	0.0009836	0.1882	0.181	CAV1/ADIPOQ/SNX33/MCTP1/MIR185/SIRPA/LGALS3/EPHA3/ATXN2/APOC1/APOC3/LRRTM1/ATG5/PRKD1/ANKRD13B/SCAMP5	16
BP	GO:0048015	phosphatidylinositol-mediated signaling	32/1884	181/18670	0.001178	0.2097	0.2017	PLCB1/PIP5K1C/PLCB3/PDGFRB/DCN/AKT1/TYRO3/SLC9A3R1/PTK2/PIK3IP1/ANGPT1/PIK3CG/FYN/ZP3/PIK3R1/CBL/MAPK3/FBXL2/KCNH1/PLCG1/PPP2R5C/LEP/CSF1R/PIK3CB/NTRK3/TSC2/PRR5L/PTPN13/SERPINA12/NKX3-1/FLT3/NTF3	32
BP	GO:0002685	regulation of leukocyte migration	34/1884	196/18670	0.001185	0.2097	0.2017	MMP14/AGER/PLCB1/HMOX1/ECM1/PYCARD/CD9/BCR/DAPK2/CSF1/TNFSF14/AKT1/ELANE/NBL1/PTGER4/THBS4/ZP3/LGALS3/PLVAP/MAPK3/IL27RA/PGF/S100A14/THY1/MSTN/CXCL14/LGMN/CYP19A1/PADI2/CXCR3/CD74/SLAMF8/EDN2/SMPD3	34
BP	GO:0001958	endochondral ossification	9/1884	28/18670	0.001238	0.2097	0.2017	DLX5/MMP14/FGFR3/NAB2/COL13A1/MEF2D/COL1A1/GNAS/SMPD3	9
BP	GO:0036075	replacement ossification	9/1884	28/18670	0.001238	0.2097	0.2017	DLX5/MMP14/FGFR3/NAB2/COL13A1/MEF2D/COL1A1/GNAS/SMPD3	9
BP	GO:0048259	regulation of receptor-mediated endocytosis	21/1884	103/18670	0.001305	0.2097	0.2017	DAB2/APOA5/TNK2/MIR185/ANGPT1/HIP1/CBL/ATXN2/APOC1/ARRB2/APOC3/LRRTM1/CD2AP/ARRB1/PIK3CB/PPT1/EGF/ANKRD13B/ARF1/PICK1/NTF3	21
BP	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling	24/1884	124/18670	0.001319	0.2097	0.2017	PIP5K1C/PDGFRB/DCN/SLC9A3R1/PTK2/PIK3IP1/ANGPT1/PIK3CG/FYN/PIK3R1/CBL/MAPK3/FBXL2/PPP2R5C/LEP/PIK3CB/NTRK3/TSC2/PRR5L/PTPN13/SERPINA12/NKX3-1/FLT3/NTF3	24
BP	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	30/1884	168/18670	0.001402	0.2097	0.2017	CDH16/PCDHB12/FAT4/PCDH12/PCDHB10/PCDHB11/NPTN/PCDHGB5/PCDHB5/PCDHA7/RET/PCDHAC2/PCDHB2/PCDHB14/PCDHA12/PLXNB2/PECAM1/PCDHA5/PCDHB4/CLSTN1/PCDHB9/PCDHA4/PCDHB15/CNTN6/PCDHA11/PIK3CB/PCDHGB1/PCDHGB7/PCDHB3/FAT2	30
BP	GO:0050770	regulation of axonogenesis	32/1884	183/18670	0.00142	0.2097	0.2017	ZSWIM5/WNT3/TRAK2/SIPA1L1/TRIM46/ZSWIM6/SYNGAP1/RUFY3/PTK2/SLITRK1/NIN/SEMA3D/SKIL/FEZF2/PLXNC1/MAP6/RET/XK/PLXNB2/SPP1/SEMA4C/ARHGAP35/MAP2/SEMA3G/TRAK1/THY1/NTRK3/PLXNA2/DCC/PLXND1/RTN4R/PAK3	32
BP	GO:0031623	receptor internalization	22/1884	111/18670	0.001494	0.2097	0.2017	RAB31/CAV1/SAG/RAMP2/CD9/ANGPT1/SNAP25/CAV3/ATXN2/ITGB2/ARRB2/LRRTM1/ARR3/ARRB1/EGF/ANKRD13B/CACNG7/CLTC/GRIA1/ARF1/PICK1/NTF3	22
BP	GO:0007411	axon guidance	44/1884	276/18670	0.001516	0.2097	0.2017	DLX5/ZSWIM5/WNT3/SCN1B/ZSWIM6/NPTN/LHX4/EPHA6/SPTBN5/PTK2/NFASC/SEMA3D/FEZF2/PLXNC1/GDF7/NTNG1/RET/FYN/TRIO/EPHA3/DOK6/PIK3R1/DPYSL5/MAPK3/PLXNB2/ISL2/SEMA4C/ARHGAP35/PLCG1/SEMA3G/PAX6/SIAH1/RAP1GAP/NKX2-1/CNTN6/CSF1R/FLRT2/PIK3CB/KIF3A/PLXNA2/DCC/PLXND1/EXT1/EGR2	44
BP	GO:0072216	positive regulation of metanephros development	6/1884	14/18670	0.001538	0.2097	0.2017	ADIPOQ/PDGFRB/EGR1/RET/WT1/MYC	6
BP	GO:0031032	actomyosin structure organization	34/1884	199/18670	0.001546	0.2097	0.2017	TMOD4/ITGB1BP1/LDB3/SYNPO2L/SLC9A1/ACTG1/CDC42BPB/PDGFRB/ARHGEF10L/DLC1/SH3PXD2B/TMOD3/PTGER4/CAV3/CORO2B/PIK3R1/PPFIA1/ASAP3/AKAP13/ROCK1/PDCD6IP/ECT2/FHOD3/TGFBR1/RAPGEF3/ARRB1/PROX1/CSRP1/WAS/CDC42/LMOD3/WASF2/CDC42BPA/ITGB5	34
BP	GO:0048017	inositol lipid-mediated signaling	32/1884	184/18670	0.001556	0.2097	0.2017	PLCB1/PIP5K1C/PLCB3/PDGFRB/DCN/AKT1/TYRO3/SLC9A3R1/PTK2/PIK3IP1/ANGPT1/PIK3CG/FYN/ZP3/PIK3R1/CBL/MAPK3/FBXL2/KCNH1/PLCG1/PPP2R5C/LEP/CSF1R/PIK3CB/NTRK3/TSC2/PRR5L/PTPN13/SERPINA12/NKX3-1/FLT3/NTF3	32
BP	GO:0097485	neuron projection guidance	44/1884	277/18670	0.00163	0.2148	0.2066	DLX5/ZSWIM5/WNT3/SCN1B/ZSWIM6/NPTN/LHX4/EPHA6/SPTBN5/PTK2/NFASC/SEMA3D/FEZF2/PLXNC1/GDF7/NTNG1/RET/FYN/TRIO/EPHA3/DOK6/PIK3R1/DPYSL5/MAPK3/PLXNB2/ISL2/SEMA4C/ARHGAP35/PLCG1/SEMA3G/PAX6/SIAH1/RAP1GAP/NKX2-1/CNTN6/CSF1R/FLRT2/PIK3CB/KIF3A/PLXNA2/DCC/PLXND1/EXT1/EGR2	44
BP	GO:0046697	decidualization	8/1884	24/18670	0.001771	0.2196	0.2112	PTGIS/STC2/JUNB/MAPK3/SPP1/TCF23/VDR/GJA1	8
BP	GO:0032273	positive regulation of protein polymerization	25/1884	134/18670	0.001814	0.2196	0.2112	BIN1/CCL26/NCK2/SLAIN2/RHOBTB2/ARPC2/FER/PYCARD/CDC42EP2/FCHSD2/NIN/BAIAP2/C15orf62/CAV3/BAIAP2L2/NAV3/FMN2/CDC42EP5/IQGAP2/WHAMMP3/WASF1/WAS/LMOD3/ARF1/PICK1	25
BP	GO:0001893	maternal placenta development	10/1884	35/18670	0.001845	0.2196	0.2112	RXRA/AKT1/PTGIS/STC2/JUNB/MAPK3/SPP1/TCF23/VDR/GJA1	10
BP	GO:0050900	leukocyte migration	71/1884	499/18670	0.001849	0.2196	0.2112	MMP14/AGER/ITGA9/CCL26/CAV1/PLCB1/HMOX1/ITGA6/ECM1/PIP5K1C/FER/SELPLG/PYCARD/CD9/BCR/LYST/DAPK2/CSF1/TNFSF14/AKT1/LCK/ITGA3/ELANE/NBL1/PTGER4/HRH1/RET/MYO1G/ANGPT1/THBS4/PIK3CG/FYN/COL1A1/SIRPA/ZP3/LGALS3/HSD3B7/PIK3R1/GPR183/CD34/PLVAP/MAPK3/IL27RA/ITGB2/PECAM1/ROCK1/PGF/S100A14/PLCG1/THY1/MSTN/NUP85/LEP/CXCL14/LGMN/S100A9/PIK3CB/CYP19A1/PADI2/CXCR3/CALCA/SFTPD/CD74/SLAMF8/EDN2/SMPD3/CHGA/FOXJ1/CD177/GP6/SCG2	71
BP	GO:0050769	positive regulation of neurogenesis	68/1884	474/18670	0.001851	0.2196	0.2112	WNT3/BIN1/TIMP2/PPP1CC/SCN1B/MMD2/FBXO31/ITGA6/LRRC7/PPARG/NPTN/CSF1/RNF112/RUFY3/CREB3L2/ALK/NCKIPSD/SLITRK1/NIN/CPNE5/ITGA3/CUX1/SKIL/BAIAP2/FEZF2/PLXNC1/NBL1/GDF7/MAP6/RET/FYN/EPHA3/SMURF1/PLXNB2/MIR200C/ARHGAP35/ECT2/ITPKA/TRAK1/PAX6/CAMK1/RAPGEF1/PRKD1/EIF4G1/NEUROD1/NDRG4/S100A9/APBB1/NTRK3/RIMS2/SS18L2/PROX1/NUMBL/GPRC5B/DYNLT1/SYT4/PLXNA2/SRRT/UNC13A/CACNG7/SOCS2/PTK6/PLXND1/ARF1/PAK3/ZMYND8/MOB2/FZD1	68
BP	GO:0048640	negative regulation of developmental growth	22/1884	113/18670	0.001898	0.2206	0.2122	WNT3/FGFR3/WWC2/TRIM46/RBP4/CDKN1A/RIPK1/PTK2/SEMA3D/STC2/CAV3/SPP1/SEMA4C/MAP2/SEMA3G/MSTN/LGMN/PI16/DCC/SOCS2/GJA1/RTN4R	22
BP	GO:0048167	regulation of synaptic plasticity	32/1884	187/18670	0.002035	0.2311	0.2223	AGER/SIPA1L1/GRIN2C/CREB1/CAMK2A/NPTN/SYNGAP1/MCTP1/CYP46A1/BAIAP2/SCGN/HRH1/SNAP25/SYNGR1/HRH2/ADORA2A/ITPKA/LRRTM1/LGMN/P2RX3/SYT12/RIMS2/SORCS2/SCT/SYT4/SHISA9/RIMS3/UNC13A/GRIA1/ARF1/PICK1/EGR2	32
BP	GO:0007409	axonogenesis	67/1884	468/18670	0.002097	0.2311	0.2223	DLX5/ZSWIM5/WNT3/TRAK2/SIPA1L1/SCN1B/TRIM46/ATL1/ZSWIM6/CREB1/NPTN/LHX4/SYNGAP1/EPHA6/RUFY3/SPTBN5/PTK2/SLITRK1/NIN/NFASC/SEMA3D/SKIL/BAIAP2/FEZF2/PLXNC1/GDF7/NTNG1/MAP6/RET/FYN/ANK3/XK/TRIO/EPHA3/DOK6/PIK3R1/DPYSL5/MAPK3/PLXNB2/SPP1/ISL2/SEMA4C/ARHGAP35/MAP2/PLCG1/SEMA3G/TRAK1/PAX6/SIAH1/THY1/RAP1GAP/NKX2-1/CNTN6/CSF1R/FLRT2/APBB1/PIK3CB/NTRK3/NUMBL/KIF3A/PLXNA2/DCC/PLXND1/RTN4R/PAK3/EXT1/EGR2	67
BP	GO:0001704	formation of primary germ layer	23/1884	121/18670	0.002105	0.2311	0.2223	MMP14/WNT3/EXT2/COL4A2/TBX19/ITGA3/COL7A1/TAL1/MIR200C/ITGB2/MSGN1/COL5A2/POU5F1/LAMA3/ITGA7/NANOG/EYA2/WLS/PRKACA/EXOC4/ELF5/SMAD2/ITGB5	23
BP	GO:0031589	cell-substrate adhesion	53/1884	354/18670	0.00226	0.2437	0.2344	MMP14/ITGB1BP1/NID1/SNED1/SLC9A1/ARPC2/ITGA6/FERMT3/UNC13D/PARVG/FER/COL13A1/VIT/BCR/CSF1/TYRO3/PTK2/ARHGEF7/ACTN1/DLC1/ITGA3/SIGLEC1/MYO1G/ANGPT1/COL1A1/EPHA3/CORO2B/PIK3R1/CD34/PPFIA1/VWF/ITGB2/PECAM1/ROCK1/TBCD/EPDR1/MMRN1/ITGA7/POSTN/LYVE1/THY1/FBLN1/ATXN3/DOCK5/PIK3CB/HSPG2/ACTN4/CDC42/MYF5/FAT2/ITGB5/RCC2/SPOCK2	53
BP	GO:1902514	regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	6/1884	15/18670	0.002346	0.2469	0.2375	SESTD1/BIN1/CACNB1/CACNA2D1/CACNB2/NPPA	6
BP	GO:0007595	lactation	12/1884	48/18670	0.002374	0.2469	0.2375	NCOR2/CAV1/CREB1/ZBTB7B/STAT5A/PRL/SERPINC1/CSN2/CSN3/VDR/SOCS2/GJA1	12
BP	GO:0031668	cellular response to extracellular stimulus	42/1884	268/18670	0.002649	0.2709	0.2605	DAPL1/P2RX7/KANK2/HMOX1/MAP1LC3B2/ITGA6/COMT/PPARG/CDKN1A/AVPR1A/P2RY2/MYH13/CBS/SLC2A1/BAIAP2/RRAGA/PDK2/FYN/COL1A1/AMBRA1/CBL/FOLR1/MAPK3/ARHGAP35/POSTN/ATG5/PRKD1/TNKS/LEP/EIF4G1/P2RX3/FOS/HIGD1A/VDR/RYR3/PIM1/GAS2L1/TAF1/AKR1C3/WIPI2/KLF10/PICK1	42
BP	GO:0010762	regulation of fibroblast migration	9/1884	31/18670	0.002738	0.2752	0.2647	ITGB1BP1/C5orf30/FER/AKT1/ARHGEF7/RFFL/PRR5L/PAK3/RCC2	9
BP	GO:0048096	chromatin-mediated maintenance of transcription	5/1884	11/18670	0.002854	0.2821	0.2713	ZMIZ2/SMARCD1/PABPC1L/PADI2/ZMIZ1	5
BP	GO:0038083	peptidyl-tyrosine autophosphorylation	10/1884	37/18670	0.002905	0.2824	0.2716	CAV1/TNK1/LCK/PTK2/TNK2/FYN/MAPK3/BMX/ITK/PTK6	10
BP	GO:0000768	syncytium formation by plasma membrane fusion	13/1884	56/18670	0.003231	0.287	0.276	CD9/ERVW-1/CAPN2/TNFSF14/EHD1/CAV3/CD109/KCNH1/CAMK1/RAPGEF3/MYF6/MYOF/MYF5	13
BP	GO:0140253	cell-cell fusion	13/1884	56/18670	0.003231	0.287	0.276	CD9/ERVW-1/CAPN2/TNFSF14/EHD1/CAV3/CD109/KCNH1/CAMK1/RAPGEF3/MYF6/MYOF/MYF5	13
BP	GO:0030833	regulation of actin filament polymerization	28/1884	162/18670	0.003231	0.287	0.276	TMOD4/BIN1/CCL26/NCK2/RHOBTB2/ARPC2/FER/PYCARD/CDC42EP2/FCHSD2/SPTBN5/BAIAP2/TMOD3/C15orf62/BAIAP2L2/FHOD3/VILL/FMN2/CDC42EP5/IQGAP2/WHAMMP3/CAPZA3/WASF1/WAS/LMOD3/ARF1/PICK1/PAK3	28
BP	GO:1901653	cellular response to peptide	56/1884	385/18670	0.003296	0.287	0.276	AGER/RAB31/ADCY9/HDAC5/CAV1/ADIPOQ/MIR106B/SLC9A1/ERRFI1/NCOA5/CREB1/AHCYL1/CACNB1/FER/PPARG/CAMK2A/NOD1/TCIRG1/RHOQ/AKT1/ZBTB7B/SH2B2/ATP6V1C1/CYP11A1/MZB1/STAT5A/PTK2/ASS1/BAIAP2/GHR/PDK2/PCK2/KLF2/FYN/PRL/ADCY5/PIK3R1/CDC5L/JAK3/ROCK1/CACNA2D1/MSTN/ADCY4/LEP/LGMN/BCL2L2/PRKACA/TSC2/NR4A1/SERPINA12/PRKCB/PIK3R3/SOCS2/SMPD3/KLF10/ATP6V0A1	56
BP	GO:0007596	blood coagulation	50/1884	336/18670	0.003346	0.287	0.276	SLC4A1/CAV1/P2RX7/FERMT3/GNA11/RCOR1/MAFK/ACTG1/CD9/SH2B2/LCK/TYRO3/RAP2B/ABAT/F2RL3/A2M/DGKZ/EHD1/PIK3CG/FYN/COL1A1/PIK3R1/CD34/VWF/MAPK3/ARRB2/SERPINB2/GP5/ADORA2A/SERPINC1/DGKE/MMRN1/HPS5/ZFPM2/VAV2/FBLN1/SERPIND1/PRKACA/P2RX3/P2RX5/ARRB1/PIK3CB/CSRP1/PRKCB/GNAS/WAS/CDC42/VKORC1/CD177/GP6	50
BP	GO:0006907	pinocytosis	7/1884	21/18670	0.003425	0.287	0.276	CAV1/PYCARD/SNX33/EHD4/MAPKAPK3/PPT1/ACTN4	7
BP	GO:0035357	peroxisome proliferator activated receptor signaling pathway	7/1884	21/18670	0.003425	0.287	0.276	RXRA/ALOX15B/PPARG/PTGIS/GPS2/LEP/ACTN4	7
BP	GO:0072224	metanephric glomerulus development	6/1884	16/18670	0.003436	0.287	0.276	ADIPOQ/PDGFRB/EGR1/RET/WT1/CD34	6
BP	GO:0065005	protein-lipid complex assembly	9/1884	32/18670	0.003474	0.287	0.276	BIN1/APOA5/DGAT1/LCAT/APOC1/APOC3/PLAGL2/PRKACA/ARF1	9
BP	GO:0010771	negative regulation of cell morphogenesis involved in differentiation	19/1884	97/18670	0.003483	0.287	0.276	WNT3/ITGB1BP1/TRAK2/TRIM46/SYNGAP1/RUFY3/PTK2/SEMA3D/SPP1/SEMA4C/MAP2/SEMA3G/POSTN/THY1/FBLN1/ACTN4/DCC/RTN4R/RCC2	19
BP	GO:0043434	response to peptide hormone	62/1884	436/18670	0.003507	0.287	0.276	RAB31/ADCY9/HDAC5/CAV1/PTPRN/ADIPOQ/SORT1/SLC9A1/ERRFI1/NCOA5/CREB1/AHCYL1/FER/PPARG/CAMK2A/TCIRG1/RHOQ/AANAT/AKT1/ZBTB7B/SH2B2/ATP6V1C1/CYP11A1/MZB1/SLC2A1/STAT5A/TIMP4/PTK2/ASS1/BAIAP2/GHR/EGR1/PDK2/PCK2/FYN/COL1A1/PRL/STC2/ADCY5/PIK3R1/CDC5L/JAK3/TH/ROCK1/TGFBR3/TNFSF10/MSTN/ADCY4/LEP/PRKACA/TSC2/NR4A1/NPPA/SERPINA12/PRKCB/PIK3R3/SOCS2/GJA1/KHK/ATP6V0A1/EGR2/NR5A1	62
BP	GO:0014065	phosphatidylinositol 3-kinase signaling	26/1884	148/18670	0.00354	0.287	0.276	PIP5K1C/PDGFRB/DCN/AKT1/TYRO3/SLC9A3R1/PTK2/PIK3IP1/ANGPT1/PIK3CG/FYN/PIK3R1/CBL/MAPK3/FBXL2/PPP2R5C/LEP/PIK3CB/NTRK3/TSC2/PRR5L/PTPN13/SERPINA12/NKX3-1/FLT3/NTF3	26
BP	GO:0097529	myeloid leukocyte migration	34/1884	210/18670	0.003811	0.287	0.276	MMP14/AGER/ITGA9/CCL26/PLCB1/PIP5K1C/CD9/DAPK2/CSF1/NBL1/PTGER4/HRH1/THBS4/PIK3CG/SIRPA/LGALS3/MAPK3/ITGB2/PECAM1/PGF/S100A14/MSTN/NUP85/LGMN/S100A9/CYP19A1/CALCA/SFTPD/CD74/SLAMF8/EDN2/CHGA/CD177/SCG2	34
BP	GO:0018108	peptidyl-tyrosine phosphorylation	53/1884	363/18670	0.003853	0.287	0.276	FGFR3/CAV1/HBEGF/ADIPOQ/MAP2K5/MIR106B/NCK2/TNK1/ERRFI1/FER/PDGFRB/IL12RB2/EPHA6/LCK/ALK/TYRO3/RAP2B/EHD4/JAK1/PTK2/TNK2/IL24/GHR/RET/ANGPT1/GPRC5A/THBS4/FYN/EPHA3/TAL1/CBL/CSPG4/MAPK3/JAK3/ITGB2/PECAM1/ARRB2/CLK1/BMX/ITK/THY1/LEP/IL12B/CSF1R/NTRK3/GPRC5B/EGF/CD74/FLT3/TNFRSF1A/PTK6/MELK/NTF3	53
BP	GO:0032271	regulation of protein polymerization	35/1884	218/18670	0.003865	0.287	0.276	TMOD4/BIN1/CCL26/NCK2/SLAIN2/RHOBTB2/ARPC2/FER/PYCARD/CDC42EP2/FCHSD2/SPTBN5/NIN/BAIAP2/TMOD3/C15orf62/CAV3/BAIAP2L2/TBCD/MAP2/FHOD3/VILL/NAV3/FMN2/CDC42EP5/IQGAP2/WHAMMP3/CAPZA3/WASF1/WAS/LMOD3/ARF1/PICK1/PAK3/CAMSAP1	35
BP	GO:0051495	positive regulation of cytoskeleton organization	36/1884	226/18670	0.003908	0.287	0.276	BIN1/CCL26/ITGB1BP1/P2RX7/SYNPO2L/NCK2/SLAIN2/RHOBTB2/ARPC2/FER/PYCARD/ARHGEF10L/CDC42EP2/FCHSD2/NIN/SH3PXD2B/BAIAP2/C15orf62/CAV3/BAIAP2L2/TGFBR1/RAPGEF3/NAV3/FMN2/CDC42EP5/IQGAP2/NTRK3/WHAMMP3/PROX1/WASF1/WAS/CDC42/LMOD3/ARF1/PICK1/NTF3	36
BP	GO:0051492	regulation of stress fiber assembly	17/1884	84/18670	0.003915	0.287	0.276	ITGB1BP1/SYNPO2L/SLC9A1/ARHGEF10L/DLC1/SH3PXD2B/PTGER4/CORO2B/PIK3R1/PPFIA1/ASAP3/ROCK1/TGFBR1/RAPGEF3/WAS/CDC42/WASF2	17
BP	GO:0006885	regulation of pH	19/1884	98/18670	0.003921	0.287	0.276	SLC4A1/SLC9A1/CA7/AVPR1A/TCIRG1/ATP6V1C1/PDK2/DMXL2/MAPK3/RHCG/SLC4A5/ATP6AP1L/PPT1/SLAMF8/SLC9A9/ROGDI/SLC4A11/ATP6V0A1/CFTR	19
BP	GO:0030038	contractile actin filament bundle assembly	19/1884	98/18670	0.003921	0.287	0.276	ITGB1BP1/SYNPO2L/SLC9A1/ARHGEF10L/DLC1/SH3PXD2B/PTGER4/CORO2B/PIK3R1/PPFIA1/ASAP3/ROCK1/TGFBR1/RAPGEF3/ARRB1/WAS/CDC42/WASF2/ITGB5	19
BP	GO:0043149	stress fiber assembly	19/1884	98/18670	0.003921	0.287	0.276	ITGB1BP1/SYNPO2L/SLC9A1/ARHGEF10L/DLC1/SH3PXD2B/PTGER4/CORO2B/PIK3R1/PPFIA1/ASAP3/ROCK1/TGFBR1/RAPGEF3/ARRB1/WAS/CDC42/WASF2/ITGB5	19
BP	GO:0006644	phospholipid metabolic process	61/1884	430/18670	0.003968	0.287	0.276	PLA2G4B/FGFR3/TTC7A/PLA2G12A/PGAP3/GPX4/PLCB1/PIGV/IP6K3/AGPAT4/PIP5K1C/GPD1/CSNK2A1/PDGFRB/CAPN2/CDS1/OSBPL10/LIPG/PLEKHA4/APOA5/MFSD2A/AGPAT3/PTK2/FITM1/DGKZ/PIK3IP1/LCAT/SMPD2/PIK3CG/OSBPL5/AMBRA1/ZP3/PIK3R1/GDPD3/APOC1/IDI1/LPCAT1/BMX/SAMD8/DGKE/PLCG1/DPM3/THEM5/PIGO/PRKD1/VAV2/NKX2-1/CSF1R/PIGA/INPP4B/SACM1L/PIK3CB/CDIPT/SGPP1/PTPN13/PIK3R3/FLT3/SOCS2/INPP5A/SMPD3/ARF1	61
BP	GO:0060135	maternal process involved in female pregnancy	14/1884	64/18670	0.004086	0.292	0.2808	HMX3/HAVCR2/RXRA/AKT1/PTGIS/ITGA3/STC2/JUNB/MAPK3/SPP1/TCF23/NPFF/VDR/GJA1	14
BP	GO:0009266	response to temperature stimulus	38/1884	243/18670	0.004256	0.2999	0.2884	BAG2/CAMK2G/SCARA5/HMOX1/METRNL/SLC9A1/ATP2A2/TRPM3/PPARG/CDKN1A/NUP153/CAMK2A/YWHAE/TRPV3/AKT1/ACADVL/TGFB1I1/CD34/MAPK3/TMEM135/ARRB2/CETN1/TRPM8/ARPP21/MSTN/ACOT11/NUP85/MYOF/DNAJB1/ATXN3/PRKACA/P2RX3/CIRBP/FOS/NR2F6/DNAJA1/POLR2D/NUP35	38
BP	GO:1902905	positive regulation of supramolecular fiber organization	33/1884	204/18670	0.004377	0.2999	0.2884	BIN1/CCL26/ITGB1BP1/SYNPO2L/NCK2/SLAIN2/RHOBTB2/ARPC2/FER/PYCARD/ARHGEF10L/CDC42EP2/FCHSD2/NIN/SH3PXD2B/BAIAP2/C15orf62/CAV3/BAIAP2L2/TGFBR1/RAPGEF3/NAV3/FMN2/CDC42EP5/IQGAP2/WHAMMP3/PROX1/WASF1/WAS/CDC42/LMOD3/ARF1/PICK1	33
BP	GO:0010761	fibroblast migration	10/1884	39/18670	0.004401	0.2999	0.2884	ITGB1BP1/C5orf30/TNS1/FER/AKT1/ARHGEF7/RFFL/PRR5L/PAK3/RCC2	10
BP	GO:0006949	syncytium formation	13/1884	58/18670	0.004462	0.2999	0.2884	CD9/ERVW-1/CAPN2/TNFSF14/EHD1/CAV3/CD109/KCNH1/CAMK1/RAPGEF3/MYF6/MYOF/MYF5	13
BP	GO:0035721	intraciliary retrograde transport	5/1884	12/18670	0.004489	0.2999	0.2884	IFT122/WDR19/TCTEX1D2/TTC21B/IFT43	5
BP	GO:0007599	hemostasis	50/1884	341/18670	0.004501	0.2999	0.2884	SLC4A1/CAV1/P2RX7/FERMT3/GNA11/RCOR1/MAFK/ACTG1/CD9/SH2B2/LCK/TYRO3/RAP2B/ABAT/F2RL3/A2M/DGKZ/EHD1/PIK3CG/FYN/COL1A1/PIK3R1/CD34/VWF/MAPK3/ARRB2/SERPINB2/GP5/ADORA2A/SERPINC1/DGKE/MMRN1/HPS5/ZFPM2/VAV2/FBLN1/SERPIND1/PRKACA/P2RX3/P2RX5/ARRB1/PIK3CB/CSRP1/PRKCB/GNAS/WAS/CDC42/VKORC1/CD177/GP6	50
BP	GO:0018212	peptidyl-tyrosine modification	53/1884	366/18670	0.004565	0.3008	0.2893	FGFR3/CAV1/HBEGF/ADIPOQ/MAP2K5/MIR106B/NCK2/TNK1/ERRFI1/FER/PDGFRB/IL12RB2/EPHA6/LCK/ALK/TYRO3/RAP2B/EHD4/JAK1/PTK2/TNK2/IL24/GHR/RET/ANGPT1/GPRC5A/THBS4/FYN/EPHA3/TAL1/CBL/CSPG4/MAPK3/JAK3/ITGB2/PECAM1/ARRB2/CLK1/BMX/ITK/THY1/LEP/IL12B/CSF1R/NTRK3/GPRC5B/EGF/CD74/FLT3/TNFRSF1A/PTK6/MELK/NTF3	53
BP	GO:0050817	coagulation	50/1884	342/18670	0.004769	0.3051	0.2934	SLC4A1/CAV1/P2RX7/FERMT3/GNA11/RCOR1/MAFK/ACTG1/CD9/SH2B2/LCK/TYRO3/RAP2B/ABAT/F2RL3/A2M/DGKZ/EHD1/PIK3CG/FYN/COL1A1/PIK3R1/CD34/VWF/MAPK3/ARRB2/SERPINB2/GP5/ADORA2A/SERPINC1/DGKE/MMRN1/HPS5/ZFPM2/VAV2/FBLN1/SERPIND1/PRKACA/P2RX3/P2RX5/ARRB1/PIK3CB/CSRP1/PRKCB/GNAS/WAS/CDC42/VKORC1/CD177/GP6	50
BP	GO:0017121	phospholipid scrambling	6/1884	17/18670	0.004861	0.3051	0.2934	SLC4A1/P2RX7/XKR8/ANO7/XKR9/XKR6	6
BP	GO:0061577	calcium ion transmembrane transport via high voltage-gated calcium channel	6/1884	17/18670	0.004861	0.3051	0.2934	SESTD1/BIN1/CACNB1/CACNA2D1/CACNB2/NPPA	6
BP	GO:0031669	cellular response to nutrient levels	37/1884	237/18670	0.004879	0.3051	0.2934	DAPL1/P2RX7/KANK2/HMOX1/MAP1LC3B2/COMT/PPARG/CDKN1A/P2RY2/MYH13/SLC2A1/BAIAP2/RRAGA/PDK2/FYN/COL1A1/AMBRA1/CBL/FOLR1/MAPK3/POSTN/ATG5/PRKD1/TNKS/LEP/EIF4G1/P2RX3/HIGD1A/VDR/RYR3/PIM1/GAS2L1/TAF1/AKR1C3/WIPI2/KLF10/PICK1	37
BP	GO:0007589	body fluid secretion	18/1884	93/18670	0.005004	0.3051	0.2934	NCOR2/CAV1/CREB1/P2RY2/ZBTB7B/STAT5A/PRL/SERPINC1/SLC4A5/ATG5/CSN2/CSN3/SCT/VDR/SOCS2/GJA1/TIFAB/ALOX12B	18
BP	GO:0048013	ephrin receptor signaling pathway	17/1884	86/18670	0.00503	0.3051	0.2934	SIPA1L1/NCK2/ARPC2/ACTG1/EPHA6/ANKS1A/PTK2/ARHGEF7/FYN/EPHA3/AP2A2/ROCK1/APH1A/VAV2/NTRK3/CDC42/PAK3	17
BP	GO:0052547	regulation of peptidase activity	63/1884	452/18670	0.00516	0.3051	0.2934	CSTB/AGER/CASC2/BIN1/TIMP2/CAV1/MAP2K5/ECM1/BIRC7/PYCARD/PPARG/CST4/CSNK2A1/NOD1/YWHAE/MAPK12/TNFSF14/AKT1/RIPK1/LCK/TIMP4/SERPINB12/DLC1/A2M/GRAMD4/MIR205/COL7A1/FYN/BID/HIP1/FURIN/CD109/MAPK3/ARRB2/RFFL/SERPINB2/TNFSF15/SPP2/ADORA2A/APLP2/SERPINC1/MIRLET7B/SLPI/TNFSF10/SERPINB7/SERPINB13/CSN2/CST2/FBLN1/LGMN/ASPH/SERPIND1/S100A9/ARRB1/MYC/SERPINA12/SERPINB5/PI16/CARD18/NKX3-1/ITIH4/CTSH/SPOCK2	63
BP	GO:0019216	regulation of lipid metabolic process	58/1884	410/18670	0.005179	0.3051	0.2934	FGFR3/NCOR2/CAV1/ADIPOQ/RXRA/THRSP/CREB1/PPARG/AVPR1A/PDGFRB/CAPN2/HCAR2/AKT1/ACADVL/APOA5/SQLE/PTK2/GPS2/LGALS12/EGR1/DGKZ/PIK3IP1/PDK2/MIR185/NPC2/OPA3/SMPD2/PIK3CG/AMBRA1/ZP3/PIK3R1/HDAC3/ORMDL3/APOC1/IDI1/LPCAT1/APOC3/SAMD8/PRKD1/LEP/VAV2/ACSL1/TREX1/SCT/PROX1/VDR/SERPINA12/PNPLA2/CD74/PIK3R3/FLT3/SOCS2/SLC45A3/TNFRSF1A/AKR1C3/SMPD3/ARF1/NR5A1	58
BP	GO:0044706	multi-multicellular organism process	35/1884	222/18670	0.005187	0.3051	0.2934	HMX3/PLA2G4B/TLE6/ENDOU/HAVCR2/RXRA/COMT/RAMP2/AVPR1A/CAPN2/AKT1/SLC2A1/PTGIS/ITGA3/SMCP/SH3PXD2B/PRL/STC2/LNPEP/JUNB/MAPK3/SPP1/PGF/TCF23/NPFF/TNP2/LEP/FBLN1/RLN2/FOS/VDR/NPPA/CALCA/GJA1/RPL29	35
BP	GO:0002691	regulation of cellular extravasation	8/1884	28/18670	0.005196	0.3051	0.2934	AGER/PLCB1/BCR/ELANE/PTGER4/PLVAP/IL27RA/THY1	8
BP	GO:0034377	plasma lipoprotein particle assembly	8/1884	28/18670	0.005196	0.3051	0.2934	APOA5/DGAT1/LCAT/APOC1/APOC3/PLAGL2/PRKACA/ARF1	8
BP	GO:0072583	clathrin-dependent endocytosis	10/1884	40/18670	0.005348	0.3051	0.2935	PIP5K1C/DAB2/FCHSD2/TNK2/HIP1/AP2A2/PIK3CB/KIAA1107/CLTC/SLC9B2	10
BP	GO:0042157	lipoprotein metabolic process	23/1884	130/18670	0.005356	0.3051	0.2935	NOTUM/PGAP3/APOL1/PIGV/GOLGA7B/LIPG/APOA5/LCAT/APOC1/MAP6D1/APOC3/DPM3/ZDHHC20/ATG5/PIGO/LEP/PIGA/PPT1/UGCG/SVIP/WIPI2/ZDHHC15/ALOX12B	23
BP	GO:0070482	response to oxygen levels	56/1884	394/18670	0.005384	0.3051	0.2935	MMP14/PSMB7/LIMD1/AGER/MALAT1/CAV1/ADIPOQ/HMOX1/MIR106B/SLC9A1/COX4I2/CREB1/LOXL2/PPARG/RAMP2/AK4/CDKN1A/PDGFRB/CAPN2/VASN/PGK1/LMNA/AKT1/SLC2A1/PTGIS/ABAT/BACH1/MB/EGR1/COL1A1/STC2/CBL/CD34/TH/KCNK3/TGFBR3/CUL2/PGF/SUV39H2/PLEKHN1/POSTN/BNIP3L/ALDH3A1/SOD3/FMN2/LEP/P2RX3/HIGD1A/EGLN2/NDRG1/DPP4/MYC/NPPA/NKX3-1/ACTN4/PICK1	56
BP	GO:0010765	positive regulation of sodium ion transport	9/1884	34/18670	0.005403	0.3051	0.2935	SCN1B/SLC9A1/SCN3B/AHCYL1/AKT1/ANK3/ACTN4/ARF1/WNK2	9
BP	GO:0097006	regulation of plasma lipoprotein particle levels	19/1884	101/18670	0.005518	0.306	0.2943	ADIPOQ/HMOX1/LIPG/APOA5/MIR33B/MIR185/DGAT1/NPC2/EHD1/LCAT/AP2A2/APOC1/APOC3/PLAGL2/KHSRP/PRKACA/CUBN/CLTC/ARF1	19
BP	GO:0030168	platelet activation	26/1884	153/18670	0.005573	0.306	0.2943	FERMT3/GNA11/ACTG1/CD9/LCK/TYRO3/RAP2B/ABAT/F2RL3/DGKZ/PIK3CG/FYN/COL1A1/PIK3R1/VWF/MAPK3/ARRB2/GP5/DGKE/VAV2/ARRB1/PIK3CB/CSRP1/PRKCB/GNAS/GP6	26
BP	GO:0051017	actin filament bundle assembly	26/1884	153/18670	0.005573	0.306	0.2943	ITGB1BP1/SYNPO2L/SLC9A1/ARHGEF10L/MYO1B/ACTN1/DLC1/SH3PXD2B/BAIAP2/PTGER4/CORO2B/PIK3R1/BAIAP2L2/PPFIA1/MARCKS/ASAP3/ROCK1/TGFBR1/RAPGEF3/FMN2/ARRB1/ACTN4/WAS/CDC42/WASF2/ITGB5	26
BP	GO:0032535	regulation of cellular component size	53/1884	370/18670	0.005688	0.3094	0.2976	TMOD4/WNT3/BIN1/CCL26/P2RX7/NCK2/TRIM46/RHOBTB2/ARPC2/CREB1/FER/AKT3/PYCARD/CDC42EP2/RUFY3/AKT1/SLC9A3R1/FCHSD2/SPTBN5/SEMA3D/BAIAP2/TMOD3/C15orf62/RET/PPP1CA/XK/CAV3/SLC12A1/BAIAP2L2/SPP1/SLC12A8/SEMA4C/ARHGAP35/MAP2/FHOD3/SEMA3G/VILL/FMN2/VAV2/CDC42EP5/IQGAP2/NTRK3/SCT/WHAMMP3/CAPZA3/WASF1/DCC/WAS/LMOD3/ARF1/RTN4R/PICK1/PAK3	53
BP	GO:0097191	extrinsic apoptotic signaling pathway	35/1884	224/18670	0.00598	0.3224	0.31	FGFR3/CAV1/P2RX7/SORT1/MAP2K5/HMOX1/ITGA6/EYA4/PYCARD/MADD/LMNA/AKT1/RIPK1/C8orf44-SGK3/SKIL/RET/FYN/BID/PPP1CA/FAIM2/LGALS3/PIK3R1/FEM1B/RFFL/TGFBR1/TNFSF10/MCL1/TNFRSF10C/TCF7L2/EYA2/BCL2L2/SGPP1/DCC/TNFRSF1A/SCG2	35
BP	GO:0072215	regulation of metanephros development	7/1884	23/18670	0.006034	0.3224	0.31	FAT4/ADIPOQ/PDGFRB/EGR1/RET/WT1/MYC	7
BP	GO:1903725	regulation of phospholipid metabolic process	17/1884	88/18670	0.006392	0.3376	0.3247	FGFR3/PDGFRB/CAPN2/PTK2/DGKZ/PIK3IP1/AMBRA1/ZP3/PIK3R1/APOC1/LPCAT1/PRKD1/VAV2/PIK3R3/FLT3/SOCS2/ARF1	17
BP	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	16/1884	81/18670	0.006434	0.3376	0.3247	CAV1/SKOR1/ADAMTSL2/PRDM16/VASN/SKIL/TGFB1I1/SMURF1/CD109/STRAP/TGFBR3/ZBTB7A/TGFBR1/NKX2-1/HTRA1/SMAD2	16
BP	GO:2001236	regulation of extrinsic apoptotic signaling pathway	26/1884	155/18670	0.00662	0.3393	0.3263	CAV1/MAP2K5/HMOX1/ITGA6/EYA4/PYCARD/MADD/LMNA/AKT1/RIPK1/C8orf44-SGK3/SKIL/RET/FYN/BID/PPP1CA/FAIM2/LGALS3/FEM1B/RFFL/TGFBR1/TNFSF10/MCL1/TCF7L2/EYA2/SCG2	26
BP	GO:0001503	ossification	56/1884	398/18670	0.006625	0.3393	0.3263	DLX5/MMP14/LIMD1/WNT3/FGFR3/EXT2/IFT80/P2RX7/TOB2/FAT4/SORT1/MRC2/NAB2/ECM1/CLEC3B/COL13A1/MEF2D/ZHX3/CSF1/TCIRG1/RRAS2/AKT1/PTK2/SH3PXD2B/PTGER4/BCOR/COL1A1/FBXO5/JUNB/GDF2/SMURF1/MAPK3/MIR200C/TOB1/SPP1/COL5A2/PRKD1/SYNCRIP/LEP/MIR675/PRKACA/SOST/BCAP29/CLEC5A/GPNMB/LRP5/GNAS/CLTC/FAM20C/GJA1/SMPD3/KLF10/MYF5/EXT1/FZD1/EGR2	56
BP	GO:0090239	regulation of histone H4 acetylation	5/1884	13/18670	0.006695	0.3393	0.3263	IWS1/KAT7/ATG5/ARRB1/CTBP1	5
BP	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading	5/1884	13/18670	0.006695	0.3393	0.3263	ITGB1BP1/POSTN/FBLN1/ACTN4/RCC2	5
BP	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	13/1884	61/18670	0.00699	0.3513	0.3378	CAV1/NCK2/LCK/SLC9A3R1/SKIL/BID/PRKRA/PLAGL2/MCL1/SIAH1/S100A9/NKX3-1/PIAS4	13
BP	GO:0008064	regulation of actin polymerization or depolymerization	29/1884	179/18670	0.00707	0.3523	0.3389	TMOD4/BIN1/CCL26/NCK2/RHOBTB2/ARPC2/FER/PYCARD/CDC42EP2/FCHSD2/SPTBN5/BAIAP2/TMOD3/C15orf62/BAIAP2L2/ARHGAP35/FHOD3/VILL/FMN2/CDC42EP5/IQGAP2/WHAMMP3/CAPZA3/WASF1/WAS/LMOD3/ARF1/PICK1/PAK3	29
BP	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	11/1884	48/18670	0.007208	0.3562	0.3426	CDH16/ARVCF/PCDH12/PCDHB10/PCDHB11/PCDHB5/PCDHB2/PCDHB14/PCDHB4/PCDHB9/PCDHB3	11
BP	GO:0030832	regulation of actin filament length	29/1884	180/18670	0.007638	0.3713	0.3571	TMOD4/BIN1/CCL26/NCK2/RHOBTB2/ARPC2/FER/PYCARD/CDC42EP2/FCHSD2/SPTBN5/BAIAP2/TMOD3/C15orf62/BAIAP2L2/ARHGAP35/FHOD3/VILL/FMN2/CDC42EP5/IQGAP2/WHAMMP3/CAPZA3/WASF1/WAS/LMOD3/ARF1/PICK1/PAK3	29
BP	GO:0051271	negative regulation of cellular component movement	54/1884	384/18670	0.007648	0.3713	0.3571	MIR193A/MITF/WNT3/BIN1/HDAC5/ITGB1BP1/PLCB1/ADIPOQ/C5orf30/MAP2K5/HMOX1/ALOX15B/PPARG/CD9/BCR/DCN/DLL4/AKT1/SRGAP3/RAP2B/SLC9A3R1/SRGAP1/MCTP1/SCAI/ACTN1/DLC1/SEMA3D/IL24/NBL1/PTGER4/SYNJ2BP/GDF2/IL27RA/MIR212/STRAP/MIR497/SEMA4C/TGFBR3/MIR338/SEMA3G/STARD13/THY1/NAV3/FBLN1/NKX2-1/NDRG4/CYP19A1/PADI2/CD74/SLAMF8/ACTN4/MIR329-1/WAS/ZMYND8	54
BP	GO:0034505	tooth mineralization	7/1884	24/18670	0.00779	0.3713	0.3571	TCIRG1/STIM1/BCOR/COL1A1/AMTN/CNNM4/FAM20C	7
BP	GO:0060396	growth hormone receptor signaling pathway	7/1884	24/18670	0.00779	0.3713	0.3571	STAT5A/PTK2/GHR/PRL/PIK3R1/JAK3/SOCS2	7
BP	GO:0061572	actin filament bundle organization	26/1884	157/18670	0.007826	0.3713	0.3571	ITGB1BP1/SYNPO2L/SLC9A1/ARHGEF10L/MYO1B/ACTN1/DLC1/SH3PXD2B/BAIAP2/PTGER4/CORO2B/PIK3R1/BAIAP2L2/PPFIA1/MARCKS/ASAP3/ROCK1/TGFBR1/RAPGEF3/FMN2/ARRB1/ACTN4/WAS/CDC42/WASF2/ITGB5	26
BP	GO:0072330	monocarboxylic acid biosynthetic process	49/1884	343/18670	0.008002	0.3754	0.361	SLC4A1/P2RX7/GPX4/ADIPOQ/ALOX15B/TECR/PTGES2/GPD1/NUP153/AVPR1A/DCN/LIPG/PGK1/GALK1/ACADVL/APOA5/PTGIS/ABAT/ACSS1/ELOVL3/CYP46A1/OSBP/MIR185/FOXK1/GCKR/HSD3B7/ACOT12/GAPDHS/CSPG4/AMACR/APOC1/ZBTB7A/APOC3/ACOT11/NUP85/ACOX2/TREX1/PFKP/PROX1/PLP1/CD74/EDN2/PRKAG3/SLC45A3/SRR/NUP35/AKR1C3/ACSS2/ALOX12B	49
BP	GO:0030641	regulation of cellular pH	17/1884	90/18670	0.008039	0.3754	0.361	SLC4A1/SLC9A1/CA7/AVPR1A/TCIRG1/ATP6V1C1/DMXL2/MAPK3/SLC4A5/ATP6AP1L/PPT1/SLAMF8/SLC9A9/ROGDI/SLC4A11/ATP6V0A1/CFTR	17
BP	GO:1903845	negative regulation of cellular response to transforming growth factor beta stimulus	16/1884	83/18670	0.008176	0.3772	0.3628	CAV1/SKOR1/ADAMTSL2/PRDM16/VASN/SKIL/TGFB1I1/SMURF1/CD109/STRAP/TGFBR3/ZBTB7A/TGFBR1/NKX2-1/HTRA1/SMAD2	16
BP	GO:0050771	negative regulation of axonogenesis	14/1884	69/18670	0.008206	0.3772	0.3628	WNT3/TRAK2/TRIM46/SYNGAP1/RUFY3/PTK2/SEMA3D/SPP1/SEMA4C/MAP2/SEMA3G/THY1/DCC/RTN4R	14
BP	GO:0007009	plasma membrane organization	19/1884	105/18670	0.008437	0.3833	0.3686	SLC4A1/BIN1/CAV1/P2RX7/FAT4/ATP2A2/SNX33/XKR8/AKT1/ANO7/BAIAP2/XKR9/ANK3/XKR6/CAV3/BAIAP2L2/MYOF/NDRG1/UGCG	19
BP	GO:1990090	cellular response to nerve growth factor stimulus	11/1884	49/18670	0.008467	0.3833	0.3686	SORT1/CREB1/AKT1/KIF1B/EHD1/CDC5L/CBL/RAPGEF1/NTRK3/WASF1/NTF3	11
BP	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	21/1884	120/18670	0.008565	0.3848	0.3701	CAV1/SKOR1/ADAMTSL2/PRDM16/DAB2/VASN/ITGA3/SKIL/CAV3/TGFB1I1/SMURF1/CD109/FOLR1/STRAP/TGFBR3/ZBTB7A/TGFBR1/NKX2-1/HTRA1/SMAD2/ING2	21
BP	GO:0030879	mammary gland development	24/1884	143/18670	0.008778	0.3898	0.3749	WNT3/NCOR2/CAV1/CREB1/CSF1/AKT1/ZBTB7B/ARHGAP5/STAT5A/ELF3/PRL/CAV3/ARHGAP35/SERPINC1/CSN2/CSN3/CSF1R/ELF5/CYP19A1/VDR/LRP5/EGF/SOCS2/GJA1	24
BP	GO:0036293	response to decreased oxygen levels	52/1884	370/18670	0.008831	0.3898	0.3749	MMP14/PSMB7/LIMD1/AGER/MALAT1/CAV1/ADIPOQ/HMOX1/MIR106B/SLC9A1/COX4I2/CREB1/LOXL2/RAMP2/AK4/CAPN2/VASN/PGK1/LMNA/AKT1/SLC2A1/PTGIS/ABAT/BACH1/MB/EGR1/STC2/CBL/CD34/TH/KCNK3/TGFBR3/CUL2/PGF/SUV39H2/PLEKHN1/POSTN/BNIP3L/ALDH3A1/SOD3/FMN2/LEP/P2RX3/HIGD1A/EGLN2/NDRG1/DPP4/MYC/NPPA/NKX3-1/ACTN4/PICK1	52
BP	GO:0030041	actin filament polymerization	29/1884	182/18670	0.008887	0.3898	0.3749	TMOD4/BIN1/CCL26/NCK2/RHOBTB2/ARPC2/FER/PYCARD/CDC42EP2/FCHSD2/CORO7/SPTBN5/BAIAP2/TMOD3/C15orf62/BAIAP2L2/FHOD3/VILL/FMN2/CDC42EP5/IQGAP2/WHAMMP3/CAPZA3/WASF1/WAS/LMOD3/ARF1/PICK1/PAK3	29
BP	GO:0006044	N-acetylglucosamine metabolic process	6/1884	19/18670	0.00894	0.3898	0.3749	MGAT3/CHST2/CHST3/GNE/CHST1/CHST4	6
BP	GO:0031397	negative regulation of protein ubiquitination	15/1884	77/18670	0.009304	0.3958	0.3807	BAG2/CAV1/N4BP1/AKT1/GPS2/SPOPL/FYN/FBXO5/ARRB2/RASD2/ATG5/ARRB1/UBR5/DNAJA1/TAF1	15
BP	GO:0071375	cellular response to peptide hormone stimulus	46/1884	321/18670	0.009413	0.3958	0.3807	RAB31/ADCY9/HDAC5/CAV1/ADIPOQ/SLC9A1/ERRFI1/NCOA5/CREB1/AHCYL1/FER/PPARG/CAMK2A/TCIRG1/RHOQ/AKT1/ZBTB7B/SH2B2/ATP6V1C1/CYP11A1/MZB1/STAT5A/PTK2/ASS1/BAIAP2/GHR/PDK2/PCK2/FYN/PRL/ADCY5/PIK3R1/CDC5L/JAK3/ROCK1/MSTN/ADCY4/LEP/PRKACA/TSC2/NR4A1/SERPINA12/PRKCB/PIK3R3/SOCS2/ATP6V0A1	46
BP	GO:0046486	glycerolipid metabolic process	57/1884	414/18670	0.009613	0.3958	0.3807	PLA2G4B/TTC7A/PLA2G12A/CAV1/PGAP3/PLCB1/THRSP/PIGV/IP6K3/AGPAT4/PIP5K1C/GPD1/CSNK2A1/PDGFRB/CAPN2/CDS1/OSBPL10/LIPG/PLEKHA4/APOA5/MFSD2A/AGPAT3/DGKZ/PCK2/DGAT1/DAGLA/LCAT/PIK3CG/OSBPL5/ZP3/CAV3/PIK3R1/LIPE/GDPD3/APOC1/LPCAT1/APOC3/BMX/DGKE/DPM3/THEM5/PNPLA5/PIGO/CSF1R/PIGA/INPP4B/SACM1L/PIK3CB/ACSL1/CDIPT/PTPN13/SERPINA12/PNPLA2/PIK3R3/SOCS2/INPP5A/ARF1	57
BP	GO:0045444	fat cell differentiation	34/1884	223/18670	0.009642	0.3958	0.3807	PLCB1/ADIPOQ/SORT1/METRNL/PRDM16/ITGA6/CREB1/PPARG/TMEM120B/AKT1/ZBTB7B/SH2B2/MEX3C/GRK5/GPS2/LGALS12/SH3PXD2B/CCDC85B/MB/MIR181A2/TRIO/TGFB1I1/ZBTB7A/ZFPM2/LEP/ARL6/TCF7L2/RUNX1T1/NR4A1/LRP5/RNASEL/CTBP1/EGR2/SDF4	34
BP	GO:0007179	transforming growth factor beta receptor signaling pathway	31/1884	199/18670	0.009667	0.3958	0.3807	LTBP2/CAV1/SKOR1/ADAMTSL2/PRDM16/CREB1/DAB2/VASN/PTK2/ITGA3/SKIL/CAV3/TGFB1I1/FURIN/SMURF1/CD109/CBL/FOLR1/MIR212/ARRB2/STRAP/TGFBR3/ZBTB7A/TGFBR1/MSTN/NKX2-1/FOS/HTRA1/SMAD2/ING2/ITGB5	31
BP	GO:0034754	cellular hormone metabolic process	22/1884	129/18670	0.00979	0.3958	0.3807	RBP4/COMT/ECE1/AANAT/CYP11A1/BCO2/CYP46A1/EGR1/DGAT1/CYP26A1/SULT1A1/SPP1/CYP21A2/RDH5/AKR1C2/CYP19A1/HSD17B11/CYP27C1/AKR1C3/ADH7/ADH1B/AKR1C1	22
BP	GO:0032386	regulation of intracellular transport	58/1884	423/18670	0.009838	0.3958	0.3807	TNNC1/ITGB1BP1/DMAP1/ADIPOQ/PPP1CC/HMOX1/ARHGAP1/TRIM46/ATP2A2/UNC13D/KHDRBS1/FER/DAB2/VPS18/SEC16B/NUP153/CAMK2A/YWHAE/IWS1/STX18/STXBP5L/RUFY3/USP36/PREPL/EHD1/SUPT6H/ANGPT1/FYN/ANK3/PIK3R1/HDAC3/MAPK3/ITGB2/ZFAND1/LAMP1/MAP2/ADORA2A/ECT2/BNIP3L/CAMK1/TCTEX1D2/RAPGEF3/LEP/TCF7L2/NDRG4/PRKACA/RIMS2/PRR5L/CACNB2/NPPA/SYT4/UBR5/PRKCB/TTC21B/RIMS3/SVIP/ARF1/PTPN14	58
BP	GO:0001706	endoderm formation	11/1884	50/18670	0.009889	0.3958	0.3807	MMP14/COL4A2/COL7A1/ITGB2/COL5A2/POU5F1/LAMA3/ITGA7/NANOG/SMAD2/ITGB5	11
BP	GO:0045672	positive regulation of osteoclast differentiation	7/1884	25/18670	0.009895	0.3958	0.3807	CREB1/CSF1/IL12B/FOS/GNAS/SLC9B2/KLF10	7
BP	GO:0071378	cellular response to growth hormone stimulus	7/1884	25/18670	0.009895	0.3958	0.3807	STAT5A/PTK2/GHR/PRL/PIK3R1/JAK3/SOCS2	7
BP	GO:0072012	glomerulus vasculature development	7/1884	25/18670	0.009895	0.3958	0.3807	PDGFRB/EGR1/ANGPT1/WT1/CD34/PECAM1/SERPINB7	7
BP	GO:0009914	hormone transport	46/1884	322/18670	0.009939	0.3958	0.3807	CAMK2G/OXCT1/PTPRN/ADIPOQ/RBP4/MIDN/CREB1/HCAR2/STXBP5L/TCIRG1/SLC2A1/MAFA/ABAT/SLC22A1/RAB11FIP5/CRYM/ADCY5/SNAP25/NADK/KCNS3/SPP1/NNAT/ADORA2A/NPFF/ILDR1/RAPGEF3/LEP/TCF7L2/NEUROD1/ARRB1/RIMS2/SCT/PCLO/CYP19A1/DPP4/LRP5/NPPA/SMAD2/GNAS/POMC/NKX3-1/GJA1/SLC9B2/SMPD3/CHGA/CFTR	46
BP	GO:1903305	regulation of regulated secretory pathway	26/1884	160/18670	0.009967	0.3958	0.3807	SYT8/HMOX1/ATP2A2/UNC13D/FER/VPS18/BCR/CAMK2A/STXBP5L/PREPL/AP1G1/SYT15/ZP3/ITGB2/LAMP1/ADORA2A/SYT12/RIMS2/CACNB2/NPPA/SYT4/PRKCB/RIMS3/SCAMP5/ARF1/CD177	26
BP	GO:0001936	regulation of endothelial cell proliferation	28/1884	176/18670	0.01022	0.3958	0.3807	MIR193A/CCL26/CAV1/HMOX1/ECM1/AKT3/PPARG/DLL4/AKT1/STAT5A/SYNJ2BP/THBS4/PRL/CCR3/GDF2/MIR497/NRARP/PGF/MIRLET7B/TGFBR1/PLCG1/PRKD1/LEP/NR4A1/PROX1/MIR329-1/GJA1/SCG2	28
BP	GO:0034308	primary alcohol metabolic process	16/1884	85/18670	0.01028	0.3958	0.3807	ALDH3B1/RBP4/GPD1/CYP11A1/ACSS1/DGAT1/SULT1A1/RDH5/AKR1C2/GPD2/CYP27C1/AKR1C3/ADH7/ACSS2/ADH1B/AKR1C1	16
BP	GO:1903844	regulation of cellular response to transforming growth factor beta stimulus	21/1884	122/18670	0.01031	0.3958	0.3807	CAV1/SKOR1/ADAMTSL2/PRDM16/DAB2/VASN/ITGA3/SKIL/CAV3/TGFB1I1/SMURF1/CD109/FOLR1/STRAP/TGFBR3/ZBTB7A/TGFBR1/NKX2-1/HTRA1/SMAD2/ING2	21
BP	GO:0098742	cell-cell adhesion via plasma-membrane adhesion molecules	40/1884	273/18670	0.01034	0.3958	0.3807	CDH16/PCDHB12/ARVCF/FAT4/ADIPOQ/MAP2K5/PCDH12/CLDN16/PCDHB10/CLDN15/PCDHB11/NPTN/PTPRF/PCDHGB5/SLITRK1/PCDHB5/PCDHA7/NTNG1/RET/PCDHAC2/PCDHB2/PCDHB14/PCDHA12/PLXNB2/ITGB2/PECAM1/PCDHA5/PCDHB4/CLSTN1/PCDHB9/PCDHA4/PCDHB15/CNTN6/PCDHA11/PIK3CB/PCDHGB1/PCDHGB7/PCDHB3/FAT2/CD177	40
BP	GO:0007565	female pregnancy	30/1884	192/18670	0.01035	0.3958	0.3807	HMX3/TLE6/ENDOU/HAVCR2/RXRA/COMT/RAMP2/CAPN2/AKT1/SLC2A1/PTGIS/ITGA3/PRL/STC2/LNPEP/JUNB/MAPK3/SPP1/PGF/TCF23/NPFF/LEP/FBLN1/RLN2/FOS/VDR/NPPA/CALCA/GJA1/RPL29	30
BP	GO:0043112	receptor metabolic process	30/1884	192/18670	0.01035	0.3958	0.3807	RAB31/CAV1/ADIPOQ/SAG/PPARG/RAMP2/CD9/ECE1/ANGPT1/REP15/SNAP25/CAV3/FURIN/SMURF1/AP2A2/ATXN2/ITGB2/ARRB2/LRRTM1/ARR3/LGMN/ARRB1/EGF/ANKRD13B/CACNG7/CLTC/GRIA1/ARF1/PICK1/NTF3	30
BP	GO:0050808	synapse organization	56/1884	408/18670	0.01083	0.3997	0.3844	PDZRN3/SIPA1L1/PCDHB10/PCDHB11/CACNB1/ACTG1/COL4A1/NPTN/SYNGAP1/RAPSN/PTPRF/PTK2/SLITRK1/ACTN1/NFASC/ITGA3/PCDHB5/BAIAP2/NTNG1/FYN/ANK3/PCDHB2/PCDHB14/LRRC24/ARHGAP22/PLXNB2/PCDHB4/CLSTN1/PCDHB9/ITPKA/COL4A5/LRRTM1/CAMK1/EIF4G1/LGMN/FLRT1/FLRT2/PDLIM5/NTRK3/PCLO/NDRG1/CACNB2/DOCK10/LRFN1/UNC13A/WASF1/PCDHB3/CDC42/WASF2/PLXND1/ARF1/PICK1/PAK3/ZMYND8/FZD1/SPOCK2	56
BP	GO:0007369	gastrulation	29/1884	185/18670	0.01107	0.3997	0.3844	MMP14/WNT3/EXT2/ADIPOQ/MAP2K5/COL4A2/TBX19/PHLDB1/ITGA3/COL7A1/TAL1/MIR200C/ITGB2/MSGN1/COL5A2/POU5F1/LAMA3/ITGA7/NANOG/EYA2/WLS/PRKACA/EXOC4/ELF5/LRP5/AMOT/SMAD2/EXT1/ITGB5	29
BP	GO:0008154	actin polymerization or depolymerization	32/1884	209/18670	0.01109	0.3997	0.3844	TMOD4/BIN1/CCL26/NCK2/RHOBTB2/ARPC2/CAP2/FER/PYCARD/CDC42EP2/FCHSD2/CORO7/SPTBN5/BAIAP2/TMOD3/C15orf62/BAIAP2L2/ARHGAP35/FHOD3/VILL/CAP1/FMN2/CDC42EP5/IQGAP2/WHAMMP3/CAPZA3/WASF1/WAS/LMOD3/ARF1/PICK1/PAK3	32
BP	GO:1901184	regulation of ERBB signaling pathway	17/1884	93/18670	0.01113	0.3997	0.3844	RHBDF1/STAM2/HBEGF/NCK2/ERRFI1/FER/AKT1/ARHGEF7/RHBDF2/GPRC5A/HIP1/CBL/LGMN/STAM/EGF/CDC42/PTK6	17
BP	GO:0043406	positive regulation of MAP kinase activity	38/1884	258/18670	0.01126	0.3997	0.3844	NEK10/AGER/P2RX7/MAP2K5/BIRC7/MADD/PDGFRB/NOD1/TNIK/RIPK1/ALK/MAP3K6/ELANE/GHR/RET/MAP3K14/PIK3CG/MAPKAPK3/CSPG4/MAPK3/AKAP13/PROK2/TGFBR1/TAB3/RAPGEF1/PDE5A/ARRB1/PIK3CB/NTRK3/ERN1/MAP3K1/EGF/CD74/FLT3/PAK3/FGD2/FPR1/NTF3	38
BP	GO:0045834	positive regulation of lipid metabolic process	24/1884	146/18670	0.01127	0.3997	0.3844	FGFR3/ADIPOQ/CREB1/PPARG/AVPR1A/PDGFRB/CAPN2/AKT1/APOA5/PTK2/DGKZ/SMPD2/AMBRA1/ZP3/APOC1/PRKD1/VAV2/SCT/PNPLA2/CD74/FLT3/SLC45A3/TNFRSF1A/SMPD3	24
BP	GO:0032147	activation of protein kinase activity	47/1884	333/18670	0.01143	0.3997	0.3844	ZFP91/ADCY9/ITGB1BP1/P2RX7/MAP2K5/BIRC7/MADD/NOD1/NEK4/TNIK/AKT1/RIPK1/ALK/MAP3K6/CAB39/GHR/RET/MAP3K14/ANGPT1/GPRC5A/MAPKAPK3/ADCY5/CSPG4/MAPK3/TNFSF15/PROK2/ECT2/TGFBR1/TAB3/RAPGEF1/ADCY4/LEP/IL12B/PRKACA/ARRB1/PIK3CB/NTRK3/ERN1/MAP3K1/TOM1L1/GPRC5B/CALCA/EGF/CD74/PAK3/FPR1/NTF3	47
BP	GO:0042058	regulation of epidermal growth factor receptor signaling pathway	16/1884	86/18670	0.01148	0.3997	0.3844	RHBDF1/STAM2/HBEGF/NCK2/ERRFI1/FER/AKT1/ARHGEF7/RHBDF2/GPRC5A/HIP1/CBL/STAM/EGF/CDC42/PTK6	16
BP	GO:0048260	positive regulation of receptor-mediated endocytosis	11/1884	51/18670	0.01149	0.3997	0.3844	DAB2/APOA5/ANGPT1/HIP1/CBL/ARRB2/ARRB1/PPT1/EGF/PICK1/NTF3	11
BP	GO:0010831	positive regulation of myotube differentiation	9/1884	38/18670	0.01164	0.3997	0.3844	MMP14/CAPN2/RBM24/TNFSF14/EHD1/CAV3/MYF6/LMOD3/MYF5	9
BP	GO:0048009	insulin-like growth factor receptor signaling pathway	9/1884	38/18670	0.01164	0.3997	0.3844	PLCB1/GIGYF1/AKT1/GHR/PIK3R1/IGFBP4/IGF2R/TSC2/NKX3-1	9
BP	GO:0048246	macrophage chemotaxis	9/1884	38/18670	0.01164	0.3997	0.3844	CSF1/LGALS3/MAPK3/MSTN/NUP85/CYP19A1/SFTPD/SLAMF8/EDN2	9
BP	GO:0060416	response to growth hormone	9/1884	38/18670	0.01164	0.3997	0.3844	AKT1/STAT5A/PTK2/ASS1/GHR/PRL/PIK3R1/JAK3/SOCS2	9
BP	GO:1903523	negative regulation of blood circulation	9/1884	38/18670	0.01164	0.3997	0.3844	AGER/BIN1/ATP2A2/PIK3CG/DOCK4/NPFF/PDE5A/LEP/DOCK5	9
BP	GO:0002577	regulation of antigen processing and presentation	6/1884	20/18670	0.0117	0.3997	0.3844	FGL2/HLA-DOB/PYCARD/NOD1/CD74/WAS	6
BP	GO:0045019	negative regulation of nitric oxide biosynthetic process	6/1884	20/18670	0.0117	0.3997	0.3844	CAV1/PTGIS/SIRPA/CD34/MIR212/KHSRP	6
BP	GO:1904406	negative regulation of nitric oxide metabolic process	6/1884	20/18670	0.0117	0.3997	0.3844	CAV1/PTGIS/SIRPA/CD34/MIR212/KHSRP	6
BP	GO:0051058	negative regulation of small GTPase mediated signal transduction	12/1884	58/18670	0.01186	0.3997	0.3844	TIMP2/TNK1/RASA3/SYNGAP1/SCAI/DLC1/ITGA3/SPRY4/ARHGAP35/RAPGEF1/CD2AP/RASAL3	12
BP	GO:0001666	response to hypoxia	50/1884	359/18670	0.01187	0.3997	0.3844	MMP14/PSMB7/LIMD1/AGER/MALAT1/CAV1/ADIPOQ/HMOX1/MIR106B/SLC9A1/COX4I2/CREB1/LOXL2/RAMP2/AK4/CAPN2/VASN/PGK1/LMNA/AKT1/SLC2A1/PTGIS/ABAT/BACH1/MB/EGR1/STC2/CD34/TH/KCNK3/TGFBR3/CUL2/PGF/SUV39H2/PLEKHN1/POSTN/BNIP3L/ALDH3A1/SOD3/FMN2/LEP/P2RX3/HIGD1A/EGLN2/NDRG1/DPP4/MYC/NPPA/NKX3-1/ACTN4	50
BP	GO:0014823	response to activity	13/1884	65/18670	0.01199	0.3997	0.3844	OXCT1/HDAC5/ADIPOQ/METRNL/CREB1/COL4A2/TPH2/CBL/TH/POSTN/MSTN/LEP/PRKAG3	13
BP	GO:0071902	positive regulation of protein serine/threonine kinase activity	47/1884	334/18670	0.01204	0.3997	0.3844	NEK10/AGER/P2RX7/ADIPOQ/MAP2K5/BIRC7/MADD/PDGFRB/NOD1/TNIK/AKT1/RIPK1/ALK/MAP3K6/ELANE/CAB39/GHR/RET/MAP3K14/PIK3CG/MAPKAPK3/CSPG4/MAPK3/AKAP13/PROK2/TGFBR1/TAB3/CAMK1/RAPGEF1/PDE5A/CCNYL1/CSF1R/ARRB1/PIK3CB/ACSL1/NTRK3/ERN1/MAP3K1/HIGD1A/PROX1/EGF/CD74/FLT3/PAK3/FGD2/FPR1/NTF3	47
BP	GO:0050804	modulation of chemical synaptic transmission	59/1884	436/18670	0.01207	0.3997	0.3844	AGER/SH3GL1/PLCB1/SIPA1L1/ADIPOQ/ATP2A2/GRIN2C/CREB1/CA7/VPS18/BCR/CAMK2A/NPTN/SYNGAP1/STXBP5L/RAPSN/ABAT/MCTP1/PREPL/CYP46A1/BAIAP2/SCGN/NTNG1/HRH1/PLCB4/FYN/SNAP25/SYNGR1/ARRB2/HRH2/CLSTN1/ADORA2A/DGKE/ITPKA/PLCG1/LRRTM1/GRM8/LGMN/PLCL1/PRKACA/P2RX3/SYT12/RIMS2/SORCS2/SCT/CACNB2/SYT4/PRKCB/SHISA9/RIMS3/UNC13A/CACNG7/DCC/GRIA1/ARF1/PICK1/ZMYND8/EGR2/NTF3	59
BP	GO:0023061	signal release	62/1884	462/18670	0.01218	0.3997	0.3844	CAMK2G/SYT8/OXCT1/P2RX7/PTPRN/ADIPOQ/RBP4/MIDN/ATP2A2/CREB1/PIP5K1C/VPS18/CAMK2A/HCAR2/STXBP5L/TCIRG1/SLC2A1/MAFA/ABAT/MCTP1/PREPL/RAB11FIP5/ADCY5/SNAP25/NADK/PPFIA1/KCNS3/SPP1/NNAT/ADORA2A/NPFF/ILDR1/RAPGEF3/LEP/TCF7L2/WLS/NEUROD1/ARRB1/SYT12/PPT1/RIMS2/SCT/PCLO/CYP19A1/CACNB2/DPP4/HRH3/LRP5/NPPA/SYT4/PRKCB/RIMS3/UNC13A/SMAD2/GNAS/POMC/NKX3-1/GJA1/SLC9B2/SMPD3/CHGA/CFTR	62
BP	GO:0071295	cellular response to vitamin	8/1884	32/18670	0.01224	0.3997	0.3844	KANK2/PPARG/COL1A1/FOLR1/POSTN/LEP/VDR/PIM1	8
BP	GO:0099632	protein transport within plasma membrane	7/1884	26/18670	0.01239	0.3997	0.3844	LRRC7/SNAP25/HIP1/AP3D1/CLSTN1/CACNG7/GRIP2	7
BP	GO:0099637	neurotransmitter receptor transport	7/1884	26/18670	0.01239	0.3997	0.3844	LRRC7/SNAP25/HIP1/AP3D1/CLSTN1/CACNG7/GRIP2	7
BP	GO:0051047	positive regulation of secretion	58/1884	428/18670	0.01239	0.3997	0.3844	AGER/OXCT1/P2RX7/HAVCR2/RBP4/ALOX15B/CREB1/UNC13D/PYCARD/AVPR1A/HCAR2/P2RY2/ABAT/AP1G1/IL17RB/PTGER4/TLR8/FRMD8/PRL/ZP3/IL1RL1/NADK/CD34/MAPK3/ITGB2/SPP1/PANX3/NNAT/PDCD6IP/LAMP1/ADORA2A/ILDR1/POSTN/ATG5/CD2AP/LEP/TCF7L2/WLS/CSF1R/ARRB1/APBB1/STAM/SCT/CYP19A1/CLEC5A/CACNB2/NPPA/SYT4/UNC13A/NKX3-1/GJA1/SCAMP5/SMPD3/ARF1/ALOX12B/CD177/CFTR/TLR1	58
BP	GO:0099177	regulation of trans-synaptic signaling	59/1884	437/18670	0.01262	0.3997	0.3844	AGER/SH3GL1/PLCB1/SIPA1L1/ADIPOQ/ATP2A2/GRIN2C/CREB1/CA7/VPS18/BCR/CAMK2A/NPTN/SYNGAP1/STXBP5L/RAPSN/ABAT/MCTP1/PREPL/CYP46A1/BAIAP2/SCGN/NTNG1/HRH1/PLCB4/FYN/SNAP25/SYNGR1/ARRB2/HRH2/CLSTN1/ADORA2A/DGKE/ITPKA/PLCG1/LRRTM1/GRM8/LGMN/PLCL1/PRKACA/P2RX3/SYT12/RIMS2/SORCS2/SCT/CACNB2/SYT4/PRKCB/SHISA9/RIMS3/UNC13A/CACNG7/DCC/GRIA1/ARF1/PICK1/ZMYND8/EGR2/NTF3	59
BP	GO:0035987	endodermal cell differentiation	10/1884	45/18670	0.01267	0.3997	0.3844	MMP14/COL4A2/COL7A1/ITGB2/COL5A2/POU5F1/LAMA3/ITGA7/NANOG/ITGB5	10
BP	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	16/1884	87/18670	0.01278	0.3997	0.3844	PDGFRB/DCN/PTK2/ANGPT1/PIK3CG/FYN/PIK3R1/CBL/LEP/PIK3CB/NTRK3/PRR5L/SERPINA12/NKX3-1/FLT3/NTF3	16
BP	GO:0032239	regulation of nucleobase-containing compound transport	5/1884	15/18670	0.01317	0.3997	0.3844	KHDRBS1/NUP153/IWS1/RIPK1/SUPT6H	5
BP	GO:0032486	Rap protein signal transduction	5/1884	15/18670	0.01317	0.3997	0.3844	TIMP2/RAP2B/CBL/RAPGEF1/RAPGEF3	5
BP	GO:0045073	regulation of chemokine biosynthetic process	5/1884	15/18670	0.01317	0.3997	0.3844	AGER/HMOX1/ELANE/EGR1/CD74	5
BP	GO:0090192	regulation of glomerulus development	5/1884	15/18670	0.01317	0.3997	0.3844	ADIPOQ/EGR1/RET/WT1/SERPINB7	5
BP	GO:0090197	positive regulation of chemokine secretion	5/1884	15/18670	0.01317	0.3997	0.3844	ALOX15B/PYCARD/IL1RL1/POSTN/CSF1R	5
BP	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway	4/1884	10/18670	0.01318	0.3997	0.3844	SLC9A3R1/PTGER1/ADCY5/GNAS	4
BP	GO:0014049	positive regulation of glutamate secretion	4/1884	10/18670	0.01318	0.3997	0.3844	P2RX7/AVPR1A/ADORA2A/SYT4	4
BP	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway	4/1884	10/18670	0.01318	0.3997	0.3844	COL4A2/COL4A1/COL1A1/COL4A5	4
BP	GO:0072203	cell proliferation involved in metanephros development	4/1884	10/18670	0.01318	0.3997	0.3844	PDGFRB/EGR1/WT1/MYC	4
BP	GO:0046580	negative regulation of Ras protein signal transduction	11/1884	52/18670	0.01328	0.3997	0.3844	TIMP2/TNK1/RASA3/SYNGAP1/SCAI/DLC1/ITGA3/SPRY4/ARHGAP35/RAPGEF1/RASAL3	11
BP	GO:1900024	regulation of substrate adhesion-dependent cell spreading	11/1884	52/18670	0.01328	0.3997	0.3844	ITGB1BP1/ARPC2/UNC13D/PTK2/ARHGEF7/POSTN/FBLN1/DOCK5/ACTN4/CDC42/RCC2	11
BP	GO:1990089	response to nerve growth factor	11/1884	52/18670	0.01328	0.3997	0.3844	SORT1/CREB1/AKT1/KIF1B/EHD1/CDC5L/CBL/RAPGEF1/NTRK3/WASF1/NTF3	11
BP	GO:1901342	regulation of vasculature development	57/1884	422/18670	0.01391	0.4127	0.3969	RHOJ/MIR193A/HDAC5/ITGB1BP1/HTATIP2/MAP2K5/HMOX1/MIR106B/ECM1/TMEM100/COL4A2/AKT3/PPARG/RAMP2/DCN/DLL4/PGK1/PTGIS/NFATC3/JAK1/EGR1/STIM1/MIR205/MIR185/KLF2/SYNJ2BP/THBS4/PRL/CCR3/WT1/TMIGD2/GDF2/CD34/MIR212/ITGB2/MIR497/ROCK1/PROK2/PGF/TSPAN12/MIRLET7B/PLCG1/STARD13/SERPINB7/RAPGEF3/PRKD1/LEP/RLN2/BMPER/HSPG2/GPNMB/MIR99B/AMOT/PRKCB/MIR329-1/CTSH/PLXND1	57
BP	GO:0007159	leukocyte cell-cell adhesion	47/1884	337/18670	0.01403	0.4127	0.3969	FGL2/AGER/CAV1/HAVCR2/CD276/NCK2/FERMT3/SELPLG/PYCARD/TNFSF14/AKT1/ZBTB7B/LCK/ASS1/ELANE/FYN/SIRPA/ZP3/LGALS3/TMIGD2/PIK3R1/AP3D1/JAK3/ITGB2/PECAM1/ROCK1/NRARP/ADORA2A/TARM1/MAD1L1/CD55/THY1/PDE5A/LEP/IL12B/S100A9/GPNMB/DPP4/SFTPD/PDCD1LG2/CD74/RASAL3/CDC42/PAK3/FOXJ1/CD177/ZMIZ1	47
BP	GO:1903321	negative regulation of protein modification by small protein conjugation or removal	16/1884	88/18670	0.0142	0.4127	0.3969	BAG2/CAV1/N4BP1/AKT1/GPS2/SPOPL/FYN/FBXO5/ARRB2/RASD2/ATG5/ARRB1/UBR5/DNAJA1/TAF1/HMG20A	16
BP	GO:0046879	hormone secretion	44/1884	312/18670	0.01422	0.4127	0.3969	CAMK2G/OXCT1/PTPRN/ADIPOQ/RBP4/MIDN/CREB1/HCAR2/STXBP5L/TCIRG1/SLC2A1/MAFA/ABAT/RAB11FIP5/ADCY5/SNAP25/NADK/KCNS3/SPP1/NNAT/ADORA2A/NPFF/ILDR1/RAPGEF3/LEP/TCF7L2/NEUROD1/ARRB1/RIMS2/SCT/PCLO/CYP19A1/DPP4/LRP5/NPPA/SMAD2/GNAS/POMC/NKX3-1/GJA1/SLC9B2/SMPD3/CHGA/CFTR	44
BP	GO:0010466	negative regulation of peptidase activity	38/1884	262/18670	0.01423	0.4127	0.3969	CSTB/BIN1/TIMP2/MAP2K5/ECM1/BIRC7/CST4/CSNK2A1/YWHAE/TNFSF14/AKT1/TIMP4/SERPINB12/A2M/COL7A1/FURIN/CD109/ARRB2/RFFL/SERPINB2/SPP2/ADORA2A/APLP2/SERPINC1/MIRLET7B/SLPI/SERPINB7/SERPINB13/CSN2/CST2/SERPIND1/ARRB1/SERPINA12/SERPINB5/PI16/CARD18/ITIH4/SPOCK2	38
BP	GO:0007229	integrin-mediated signaling pathway	18/1884	103/18670	0.01441	0.4127	0.3969	ITGA9/ITGB1BP1/ITGA6/FERMT3/PTK2/ITGA3/ITGB2/LAT/LAMA3/ITGA7/THY1/PRKD1/PLP1/ADAM11/CDC42/ITGB5/CD177/RCC2	18
BP	GO:0051924	regulation of calcium ion transport	37/1884	254/18670	0.01445	0.4127	0.3969	CAMK2G/SESTD1/BIN1/CAV1/P2RX7/BEST1/SLC9A1/CACNB1/RCVRN/PDGFRB/CAMK2A/YWHAE/TRPV3/F2RL3/STIM1/PIK3CG/FYN/STAC2/STC2/LGALS3/CAV3/ARRB2/CACNA2D1/ADORA2A/PLCG1/THY1/ATG5/PRKACA/P2RX3/P2RX5/TRDN/CACNB2/NPPA/EGF/GRIN3B/AHNAK/GJA1	37
BP	GO:0097164	ammonium ion metabolic process	31/1884	205/18670	0.01451	0.4127	0.3969	PLA2G4B/ALDH7A1/PLA2G12A/COMT/TPH2/CSNK2A1/CAPN2/DMGDH/CDS1/ODC1/APOA5/MFSD2A/ABAT/LCAT/SMPD2/GDPD3/SATL1/ITGB2/TH/APOC1/AGMAT/LPCAT1/SAMD8/SRM/BHMT/AKR1C2/SGPP1/MAOA/AKR1C3/SMPD3/AKR1C1	31
BP	GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	21/1884	126/18670	0.01466	0.4127	0.3969	CAV1/SKOR1/ADAMTSL2/PRDM16/VASN/SKIL/NBL1/TGFB1I1/SMURF1/CD109/TOB1/STRAP/TGFBR3/ZBTB7A/TGFBR1/NKX2-1/BMPER/SOST/HTRA1/SMAD2/FZD1	21
BP	GO:0071675	regulation of mononuclear cell migration	10/1884	46/18670	0.01477	0.4127	0.3969	AGER/PLCB1/CSF1/NBL1/LGALS3/MAPK3/S100A14/MSTN/LGMN/SLAMF8	10
BP	GO:0046683	response to organophosphorus	22/1884	134/18670	0.015	0.4127	0.3969	P2RX7/PTPRN/ADIPOQ/GPD1/P2RY2/AANAT/ASS1/PIK3CG/COL1A1/WT1/JUNB/RAPGEF1/ALDH3A1/MMP19/RAPGEF3/P2RX3/P2RX5/FOS/RYR3/TAF1/AKR1C1/CFTR	22
BP	GO:0006067	ethanol metabolic process	6/1884	21/18670	0.01501	0.4127	0.3969	ALDH3B1/ACSS1/SULT1A1/ADH7/ACSS2/ADH1B	6
BP	GO:0042135	neurotransmitter catabolic process	6/1884	21/18670	0.01501	0.4127	0.3969	ALDH7A1/COMT/DMGDH/ABAT/BHMT/MAOA	6
BP	GO:0051412	response to corticosterone	6/1884	21/18670	0.01501	0.4127	0.3969	CDKN1A/AVPR1A/AANAT/TH/NTRK3/FOS	6
BP	GO:1900182	positive regulation of protein localization to nucleus	14/1884	74/18670	0.01508	0.4127	0.3969	NMD3/DMAP1/AKT1/GLIS2/KAT7/FYN/PIK3R1/HDAC3/ECT2/TRIM8/CD2AP/LEP/CCT4/UBR5	14
BP	GO:0006066	alcohol metabolic process	50/1884	364/18670	0.01515	0.4127	0.3969	ALDH3B1/PLCB1/APOL1/RXRA/RBP4/IP6K3/TRERF1/PLCB3/GPD1/GALK1/CYP11A1/ACADVL/APOA5/SQLE/ACSS1/CYP46A1/PCK2/HRH1/MIR185/DGAT1/NPC2/LCAT/PLCB4/OSBPL5/HSD3B7/LIPE/SULT1A1/APOC1/IDI1/ITPKA/PLCG1/RDH5/LEP/MYOF/PLCL1/INPP4B/AKR1C2/GPD2/SGPP1/CUBN/VDR/SERPINA12/CYP27C1/INPP5A/AKR1C3/ADH7/ACSS2/ADH1B/AKR1C1/CFTR	50
BP	GO:0042073	intraciliary transport	11/1884	53/18670	0.01527	0.4127	0.3969	IFT80/LCA5L/IFT74/IFT122/WDR19/TCTEX1D2/IFT81/CLUAP1/KIF3A/TTC21B/IFT43	11
BP	GO:1903307	positive regulation of regulated secretory pathway	11/1884	53/18670	0.01527	0.4127	0.3969	UNC13D/AP1G1/ZP3/ITGB2/LAMP1/CACNB2/NPPA/SYT4/SCAMP5/ARF1/CD177	11
BP	GO:1905517	macrophage migration	11/1884	53/18670	0.01527	0.4127	0.3969	MMP14/CD9/CSF1/LGALS3/MAPK3/MSTN/NUP85/CYP19A1/SFTPD/SLAMF8/EDN2	11
BP	GO:0060143	positive regulation of syncytium formation by plasma membrane fusion	7/1884	27/18670	0.0153	0.4127	0.3969	CAPN2/TNFSF14/EHD1/CAMK1/RAPGEF3/MYF6/MYF5	7
BP	GO:0061437	renal system vasculature development	7/1884	27/18670	0.0153	0.4127	0.3969	PDGFRB/EGR1/ANGPT1/WT1/CD34/PECAM1/SERPINB7	7
BP	GO:0061440	kidney vasculature development	7/1884	27/18670	0.0153	0.4127	0.3969	PDGFRB/EGR1/ANGPT1/WT1/CD34/PECAM1/SERPINB7	7
BP	GO:0071559	response to transforming growth factor beta	37/1884	255/18670	0.01531	0.4127	0.3969	LTBP2/CAV1/SKOR1/ADAMTSL2/PRDM16/CREB1/COL4A2/CLEC3B/DAB2/VASN/PTK2/ITGA3/SKIL/FYN/COL1A1/CAV3/TGFB1I1/FURIN/SMURF1/CD109/CBL/FOLR1/MIR212/ARRB2/STRAP/ROCK1/TGFBR3/ZBTB7A/TGFBR1/POSTN/MSTN/NKX2-1/FOS/HTRA1/SMAD2/ING2/ITGB5	37
BP	GO:0046890	regulation of lipid biosynthetic process	30/1884	198/18670	0.01559	0.415	0.3992	ADIPOQ/THRSP/CREB1/AVPR1A/CAPN2/AKT1/ACADVL/APOA5/SQLE/EGR1/MIR185/SMPD2/ZP3/ORMDL3/APOC1/IDI1/LPCAT1/APOC3/SAMD8/LEP/TREX1/PROX1/VDR/SERPINA12/CD74/SLC45A3/TNFRSF1A/AKR1C3/SMPD3/NR5A1	30
BP	GO:0046488	phosphatidylinositol metabolic process	27/1884	174/18670	0.01571	0.415	0.3992	TTC7A/PLA2G12A/PGAP3/PLCB1/PIGV/IP6K3/PIP5K1C/PDGFRB/CDS1/PLEKHA4/PIK3CG/ZP3/PIK3R1/BMX/DPM3/PIGO/CSF1R/PIGA/INPP4B/SACM1L/PIK3CB/CDIPT/PTPN13/PIK3R3/SOCS2/INPP5A/ARF1	27
BP	GO:1903532	positive regulation of secretion by cell	54/1884	399/18670	0.01574	0.415	0.3992	AGER/OXCT1/P2RX7/HAVCR2/RBP4/ALOX15B/CREB1/UNC13D/PYCARD/AVPR1A/HCAR2/ABAT/AP1G1/IL17RB/PTGER4/TLR8/FRMD8/ZP3/IL1RL1/NADK/CD34/MAPK3/ITGB2/SPP1/PANX3/NNAT/PDCD6IP/LAMP1/ADORA2A/ILDR1/POSTN/CD2AP/LEP/TCF7L2/WLS/CSF1R/ARRB1/APBB1/STAM/SCT/CYP19A1/CLEC5A/CACNB2/NPPA/SYT4/UNC13A/NKX3-1/GJA1/SCAMP5/SMPD3/ARF1/CD177/CFTR/TLR1	54
BP	GO:0046822	regulation of nucleocytoplasmic transport	18/1884	104/18670	0.01583	0.415	0.3992	DMAP1/PPP1CC/KHDRBS1/NUP153/YWHAE/IWS1/SUPT6H/ANGPT1/PIK3R1/HDAC3/ECT2/CAMK1/RAPGEF3/LEP/TCF7L2/PRKACA/UBR5/PTPN14	18
BP	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	18/1884	104/18670	0.01583	0.415	0.3992	MAP2K5/HMOX1/ITGA6/EYA4/LMNA/AKT1/RIPK1/C8orf44-SGK3/FYN/FAIM2/LGALS3/RFFL/TGFBR1/TNFSF10/MCL1/TCF7L2/EYA2/SCG2	18
BP	GO:0052548	regulation of endopeptidase activity	57/1884	425/18670	0.01588	0.415	0.3992	CSTB/AGER/CASC2/BIN1/TIMP2/MAP2K5/BIRC7/PYCARD/PPARG/CST4/CSNK2A1/NOD1/YWHAE/TNFSF14/AKT1/RIPK1/LCK/TIMP4/SERPINB12/DLC1/A2M/GRAMD4/MIR205/COL7A1/FYN/BID/HIP1/FURIN/CD109/ARRB2/RFFL/SERPINB2/TNFSF15/SPP2/ADORA2A/APLP2/SERPINC1/MIRLET7B/SLPI/TNFSF10/SERPINB7/SERPINB13/CSN2/CST2/LGMN/ASPH/SERPIND1/S100A9/ARRB1/MYC/SERPINA12/SERPINB5/CARD18/NKX3-1/ITIH4/CTSH/SPOCK2	57
BP	GO:0007162	negative regulation of cell adhesion	41/1884	289/18670	0.01593	0.415	0.3992	MMP14/FGL2/ITGB1BP1/HAVCR2/ADIPOQ/MAP2K5/CD9/CDSN/AKT1/ZBTB7B/LPXN/ABAT/PTK2/ASS1/DLC1/PLXNC1/ANGPT1/COL1A1/LGALS3/CORO2B/PIK3R1/JAK3/PLXNB2/NRARP/TBCD/ADORA2A/TARM1/MAD1L1/POSTN/PDE5A/FBLN1/MIR675/GPNMB/SFTPD/PDCD1LG2/CD74/PLXNA2/ACTN4/PLXND1/FOXJ1/RCC2	41
BP	GO:0035735	intraciliary transport involved in cilium assembly	9/1884	40/18670	0.01626	0.415	0.3992	IFT80/IFT74/IFT122/WDR19/IFT81/CLUAP1/KIF3A/TTC21B/IFT43	9
BP	GO:0016925	protein sumoylation	15/1884	82/18670	0.01635	0.415	0.3992	ZMIZ2/SUMO2/NUP153/RNF212/EGR1/TOLLIP/CBX4/RASD2/NUP85/NSMCE2/PIAS4/NUP35/HMG20A/EGR2/ZMIZ1	15
BP	GO:0015918	sterol transport	19/1884	112/18670	0.01644	0.415	0.3992	GRAMD1B/CAV1/ADIPOQ/PPARG/OSBPL10/LIPG/APOA5/MIR33B/GPS2/OSBP/NPC2/LCAT/OSBPL5/APOC1/APOC3/LEP/EGF/AKR1C1/CFTR	19
BP	GO:1903510	mucopolysaccharide metabolic process	19/1884	112/18670	0.01644	0.415	0.3992	LUM/SLC9A1/CHST2/CHST3/DCN/AKT1/ANGPT1/ST3GAL3/PRELP/CSPG4/CHST1/LYVE1/B4GALT2/EGF/PIM1/CLTC/ITIH4/SMPD3/SPOCK2	19
BP	GO:0030073	insulin secretion	31/1884	207/18670	0.01651	0.415	0.3992	CAMK2G/OXCT1/PTPRN/RBP4/MIDN/STXBP5L/TCIRG1/SLC2A1/MAFA/ABAT/RAB11FIP5/ADCY5/SNAP25/NADK/KCNS3/NNAT/NPFF/RAPGEF3/LEP/TCF7L2/NEUROD1/ARRB1/RIMS2/PCLO/DPP4/LRP5/SMAD2/GJA1/SLC9B2/CHGA/CFTR	31
BP	GO:0032231	regulation of actin filament bundle assembly	17/1884	97/18670	0.01663	0.415	0.3992	ITGB1BP1/SYNPO2L/SLC9A1/ARHGEF10L/DLC1/SH3PXD2B/PTGER4/CORO2B/PIK3R1/PPFIA1/ASAP3/ROCK1/TGFBR1/RAPGEF3/WAS/CDC42/WASF2	17
BP	GO:0051650	establishment of vesicle localization	41/1884	290/18670	0.0168	0.415	0.3992	SYT8/P2RX7/TRAK2/TRAPPC3/TRIM46/ATP2A2/PIP5K1C/PEF1/VPS18/SEC16B/CAMK2A/STXBP5L/KIF1B/PPP6R3/PREPL/COL7A1/CTSC/SNAP25/AP3D1/MREG/FOLR1/MAP2/ADORA2A/TRAK1/ARL6/EXOC4/SYT12/RIMS2/PCLO/CACNB2/SYT4/KIAA1107/KIF3A/PRKCB/RIMS3/UNC13A/ACTN4/DCTN2/GRIA1/MLPH/ARF1	41
BP	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	28/1884	183/18670	0.01681	0.415	0.3992	TRAF5/SECTM1/ADIPOQ/CXXC5/HMOX1/TRIM22/ECM1/NOD1/AKT1/RIPK1/MAP3K14/FYN/S100A4/AKAP13/ECT2/NDFIP1/TAB3/TNFSF10/PRKD1/TRIM8/WLS/SLC20A1/GPRC5B/CD74/PRKCB/GJA1/TNFRSF1A/TNFRSF19	28
BP	GO:0051181	cofactor transport	10/1884	47/18670	0.01711	0.415	0.3992	P2RX7/SLC25A45/SLC48A1/SLC9A3R1/SLC25A21/LMBRD1/FOLR1/SLC33A1/PPT1/CUBN	10
BP	GO:2001239	regulation of extrinsic apoptotic signaling pathway in absence of ligand	10/1884	47/18670	0.01711	0.415	0.3992	MAP2K5/EYA4/AKT1/RIPK1/C8orf44-SGK3/RET/FYN/PPP1CA/MCL1/EYA2	10
BP	GO:0030595	leukocyte chemotaxis	33/1884	224/18670	0.01719	0.415	0.3992	ITGA9/CCL26/PIP5K1C/LYST/DAPK2/CSF1/TNFSF14/NBL1/HRH1/THBS4/PIK3CG/LGALS3/HSD3B7/GPR183/MAPK3/ITGB2/PGF/S100A14/MSTN/NUP85/CXCL14/LGMN/S100A9/CYP19A1/PADI2/CXCR3/CALCA/SFTPD/CD74/SLAMF8/EDN2/CHGA/SCG2	33
BP	GO:0034333	adherens junction assembly	16/1884	90/18670	0.01741	0.415	0.3992	MMP14/ITGB1BP1/SLC9A1/PIP5K1C/RAMP2/BCR/PTK2/ARHGEF7/ACTN1/DLC1/EPHA3/CORO2B/ROCK1/TBCD/THY1/RCC2	16
BP	GO:0071560	cellular response to transforming growth factor beta stimulus	36/1884	249/18670	0.01745	0.415	0.3992	LTBP2/CAV1/SKOR1/ADAMTSL2/PRDM16/CREB1/COL4A2/CLEC3B/DAB2/VASN/PTK2/ITGA3/SKIL/FYN/COL1A1/CAV3/TGFB1I1/FURIN/SMURF1/CD109/CBL/FOLR1/MIR212/ARRB2/STRAP/TGFBR3/ZBTB7A/TGFBR1/POSTN/MSTN/NKX2-1/FOS/HTRA1/SMAD2/ING2/ITGB5	36
BP	GO:0014048	regulation of glutamate secretion	5/1884	16/18670	0.01759	0.415	0.3992	P2RX7/AVPR1A/ADORA2A/HRH3/SYT4	5
BP	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation	5/1884	16/18670	0.01759	0.415	0.3992	FCHSD2/WASF1/WAS/ARF1/PICK1	5
BP	GO:0042033	chemokine biosynthetic process	5/1884	16/18670	0.01759	0.415	0.3992	AGER/HMOX1/ELANE/EGR1/CD74	5
BP	GO:0042448	progesterone metabolic process	5/1884	16/18670	0.01759	0.415	0.3992	CYP46A1/EGR1/AKR1C2/AKR1C3/AKR1C1	5
BP	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter	5/1884	16/18670	0.01759	0.415	0.3992	SYT8/ATP2A2/RIMS2/SYT4/RIMS3	5
BP	GO:0050755	chemokine metabolic process	5/1884	16/18670	0.01759	0.415	0.3992	AGER/HMOX1/ELANE/EGR1/CD74	5
BP	GO:0055012	ventricular cardiac muscle cell differentiation	5/1884	16/18670	0.01759	0.415	0.3992	RXRA/NKX2-6/LMNA/ATG5/PROX1	5
BP	GO:0072109	glomerular mesangium development	5/1884	16/18670	0.01759	0.415	0.3992	PDGFRB/EGR1/WT1/CD34/SERPINB7	5
BP	GO:0090153	regulation of sphingolipid biosynthetic process	5/1884	16/18670	0.01759	0.415	0.3992	SMPD2/ORMDL3/SAMD8/TNFRSF1A/SMPD3	5
BP	GO:1905038	regulation of membrane lipid metabolic process	5/1884	16/18670	0.01759	0.415	0.3992	SMPD2/ORMDL3/SAMD8/TNFRSF1A/SMPD3	5
BP	GO:2000303	regulation of ceramide biosynthetic process	5/1884	16/18670	0.01759	0.415	0.3992	SMPD2/ORMDL3/SAMD8/TNFRSF1A/SMPD3	5
BP	GO:0032594	protein transport within lipid bilayer	8/1884	34/18670	0.01764	0.415	0.3992	LRRC7/SNAP25/HIP1/AP3D1/CLSTN1/ARL6/CACNG7/GRIP2	8
BP	GO:0034329	cell junction assembly	35/1884	241/18670	0.01773	0.4155	0.3996	MMP14/ARVCF/ITGB1BP1/CAV1/TNS1/SLC9A1/ITGA6/PIP5K1C/RAMP2/ACTG1/CD9/BCR/GPBAR1/PTK2/ARHGEF7/ACTN1/DLC1/NFASC/EPHA3/CORO2B/PECAM1/ROCK1/PDCD6IP/TBCD/ECT2/LAMA3/RAPGEF1/THY1/PRKACA/FBLIM1/ACTN4/PKP1/GJA1/CDC42/RCC2	35
BP	GO:0000187	activation of MAPK activity	24/1884	152/18670	0.01797	0.4195	0.4034	P2RX7/MAP2K5/BIRC7/MADD/NOD1/RIPK1/ALK/MAP3K6/GHR/RET/MAPKAPK3/CSPG4/MAPK3/PROK2/TAB3/ARRB1/PIK3CB/NTRK3/ERN1/EGF/CD74/PAK3/FPR1/NTF3	24
BP	GO:0030203	glycosaminoglycan metabolic process	25/1884	160/18670	0.01805	0.4197	0.4036	EXT2/LUM/SLC9A1/CHST2/PDGFRB/CHST3/DCN/AKT1/EXTL1/ANGPT1/ST3GAL3/PRELP/CSPG4/CHST1/SGSH/LYVE1/B4GALT2/HSPG2/EGF/PIM1/CLTC/ITIH4/SMPD3/EXT1/SPOCK2	25
BP	GO:0007160	cell-matrix adhesion	33/1884	225/18670	0.01825	0.4206	0.4045	MMP14/ITGB1BP1/NID1/SNED1/SLC9A1/ITGA6/PARVG/COL13A1/BCR/CSF1/PTK2/ARHGEF7/ACTN1/DLC1/ITGA3/SIGLEC1/EPHA3/CORO2B/PIK3R1/CD34/PPFIA1/ITGB2/PECAM1/ROCK1/EPDR1/ITGA7/POSTN/LYVE1/THY1/PIK3CB/MYF5/ITGB5/RCC2	33
BP	GO:0010951	negative regulation of endopeptidase activity	36/1884	250/18670	0.01846	0.4206	0.4045	CSTB/BIN1/TIMP2/MAP2K5/BIRC7/CST4/CSNK2A1/YWHAE/TNFSF14/AKT1/TIMP4/SERPINB12/A2M/COL7A1/FURIN/CD109/ARRB2/RFFL/SERPINB2/SPP2/ADORA2A/APLP2/SERPINC1/MIRLET7B/SLPI/SERPINB7/SERPINB13/CSN2/CST2/SERPIND1/ARRB1/SERPINA12/SERPINB5/CARD18/ITIH4/SPOCK2	36
BP	GO:0017157	regulation of exocytosis	32/1884	217/18670	0.01849	0.4206	0.4045	SYT8/HMOX1/ATP2A2/UNC13D/FER/VPS18/BCR/CAMK2A/STXBP5L/PREPL/AP1G1/SYT15/ZP3/RAB33B/ITGB2/PDCD6IP/LAMP1/ADORA2A/SYT12/STAM/RIMS2/PCLO/CACNB2/NPPA/SYT4/PRKCB/RIMS3/SCAMP5/SMPD3/ARF1/CD177/CFTR	32
BP	GO:0050920	regulation of chemotaxis	32/1884	217/18670	0.01849	0.4206	0.4045	ZSWIM5/WNT3/AGER/CCL26/ZSWIM6/PDGFRB/DAPK2/CSF1/TNFSF14/SEMA3D/ELANE/FEZF2/NBL1/THBS4/GPR183/MAPK3/SEMA4C/PGF/S100A14/SEMA3G/MSTN/PRKD1/CXCL14/LGMN/NTRK3/CYP19A1/PADI2/CD74/SLAMF8/EDN2/SCG2/NTF3	32
BP	GO:0007492	endoderm development	14/1884	76/18670	0.01882	0.4206	0.4045	MMP14/SSBP3/COL4A2/COL7A1/ITGB2/COL5A2/POU5F1/LAMA3/ITGA7/NANOG/NKX2-1/SMAD2/EXT1/ITGB5	14
BP	GO:0033622	integrin activation	6/1884	22/18670	0.01892	0.4206	0.4045	PIEZO1/ITGB1BP1/FERMT3/MZB1/PTGER4/FBLIM1	6
BP	GO:0036119	response to platelet-derived growth factor	6/1884	22/18670	0.01892	0.4206	0.4045	ERRFI1/CREB1/FER/PDGFRB/FYN/CBL	6
BP	GO:0007520	myoblast fusion	9/1884	41/18670	0.01902	0.4206	0.4045	CD9/CAPN2/TNFSF14/EHD1/CAV3/KCNH1/MYF6/MYOF/MYF5	9
BP	GO:0032908	regulation of transforming growth factor beta1 production	4/1884	11/18670	0.01908	0.4206	0.4045	LUM/FURIN/SERPINB7/CD2AP	4
BP	GO:0034379	very-low-density lipoprotein particle assembly	4/1884	11/18670	0.01908	0.4206	0.4045	DGAT1/APOC1/APOC3/ARF1	4
BP	GO:0055015	ventricular cardiac muscle cell development	4/1884	11/18670	0.01908	0.4206	0.4045	NKX2-6/LMNA/ATG5/PROX1	4
BP	GO:0072110	glomerular mesangial cell proliferation	4/1884	11/18670	0.01908	0.4206	0.4045	PDGFRB/EGR1/WT1/SERPINB7	4
BP	GO:0090193	positive regulation of glomerulus development	4/1884	11/18670	0.01908	0.4206	0.4045	ADIPOQ/EGR1/RET/SERPINB7	4
BP	GO:1905941	positive regulation of gonad development	4/1884	11/18670	0.01908	0.4206	0.4045	WT1/ZP3/ZFPM2/NR5A1	4
BP	GO:0034381	plasma lipoprotein particle clearance	13/1884	69/18670	0.01938	0.424	0.4078	ADIPOQ/HMOX1/LIPG/MIR33B/MIR185/NPC2/EHD1/AP2A2/APOC1/APOC3/KHSRP/CUBN/CLTC	13
BP	GO:0042698	ovulation cycle	13/1884	69/18670	0.01938	0.424	0.4078	NCOR2/PTPRN/TYRO3/TIMP4/EGR1/ZP3/ARRB2/GAS2/MMP19/MSTN/LEP/ARRB1/NR5A1	13
BP	GO:1903727	positive regulation of phospholipid metabolic process	10/1884	48/18670	0.01972	0.4278	0.4114	FGFR3/PDGFRB/CAPN2/PTK2/DGKZ/AMBRA1/ZP3/PRKD1/VAV2/FLT3	10
BP	GO:0046824	positive regulation of nucleocytoplasmic transport	12/1884	62/18670	0.01977	0.4278	0.4114	DMAP1/KHDRBS1/YWHAE/PIK3R1/HDAC3/ECT2/CAMK1/RAPGEF3/LEP/TCF7L2/PRKACA/UBR5	12
BP	GO:1902305	regulation of sodium ion transmembrane transport	12/1884	62/18670	0.01977	0.4278	0.4114	FXYD3/SCN1B/SLC9A1/SCN3B/SLC9A3R1/ANK3/CAV3/COMMD1/ACTN4/FXYD2/ARF1/WNK2	12
BP	GO:0043551	regulation of phosphatidylinositol 3-kinase activity	11/1884	55/18670	0.01992	0.4279	0.4115	FGFR3/PDGFRB/PTK2/PIK3IP1/AMBRA1/PIK3R1/PRKD1/VAV2/PIK3R3/FLT3/SOCS2	11
BP	GO:0043954	cellular component maintenance	11/1884	55/18670	0.01992	0.4279	0.4115	SYNGAP1/ITGA3/SUPT6H/FYN/ITPKA/CSF1R/PCLO/TPRN/PICK1/ZMYND8/CD177	11
BP	GO:0051453	regulation of intracellular pH	15/1884	84/18670	0.0201	0.4303	0.4138	SLC4A1/SLC9A1/CA7/AVPR1A/TCIRG1/ATP6V1C1/DMXL2/SLC4A5/PPT1/SLAMF8/SLC9A9/ROGDI/SLC4A11/ATP6V0A1/CFTR	15
BP	GO:0040013	negative regulation of locomotion	53/1884	396/18670	0.02019	0.4306	0.4141	TRIM35/MIR193A/MITF/WNT3/HDAC5/ITGB1BP1/PLCB1/ADIPOQ/C5orf30/MAP2K5/HMOX1/ALOX15B/PPARG/BCR/DCN/DLL4/AKT1/SRGAP3/RAP2B/SLC9A3R1/SRGAP1/MCTP1/SCAI/DLC1/SEMA3D/ELANE/IL24/NBL1/PTGER4/SYNJ2BP/GDF2/IL27RA/MIR212/STRAP/MIR497/SEMA4C/ADORA2A/MIR338/SEMA3G/STARD13/THY1/TRIM8/NAV3/FBLN1/NKX2-1/NDRG4/CYP19A1/PADI2/CD74/SLAMF8/MIR329-1/WAS/ZMYND8	53
BP	GO:0061337	cardiac conduction	23/1884	146/18670	0.02072	0.4387	0.4219	FXYD3/BIN1/CAV1/SCN1B/SLC9A1/ATP2A2/SCN3B/AHCYL1/CACNB1/YWHAE/KCNK15/STIM1/KCNK3/CACNA2D1/ASPH/PRKACA/TRDN/CACNB2/NPPA/RYR3/CACNG7/FXYD2/GJA1	23
BP	GO:1990778	protein localization to cell periphery	43/1884	311/18670	0.02074	0.4387	0.4219	MMP14/SLC4A1/TTC7A/RAB31/ARHGEF16/ITGB1BP1/CAV1/ADIPOQ/LRRC7/GRIN2C/SCN3B/DAB2/RAMP2/TSPAN15/TNIK/RHOQ/RAPSN/AKT1/SLC9A3R1/KIF1B/NFASC/ITGA3/PREPL/STAC2/ANK3/LGALS3/EPHA3/SNAP25/CAV3/PIK3R1/SMURF1/PPFIA1/RAPGEF6/ROCK1/CLSTN1/GPR158/WDR19/ARL6/CACNB2/CLTC/LYPD1/TNFRSF1A/GRIP2	43
BP	GO:0055067	monovalent inorganic cation homeostasis	24/1884	154/18670	0.02079	0.4387	0.4219	SLC4A1/SLC9A1/COMT/CA7/AVPR1A/TCIRG1/ATP6V1C1/PDK2/DMXL2/SLC12A1/MAPK3/RHCG/SLC12A8/ADORA2A/SLC4A5/ATP6AP1L/PPT1/SLAMF8/SLC9A9/SCNN1A/ROGDI/SLC4A11/ATP6V0A1/CFTR	24
BP	GO:0030301	cholesterol transport	17/1884	100/18670	0.02198	0.4622	0.4446	CAV1/ADIPOQ/PPARG/LIPG/APOA5/MIR33B/GPS2/OSBP/NPC2/LCAT/OSBPL5/APOC1/APOC3/LEP/EGF/AKR1C1/CFTR	17
BP	GO:0002028	regulation of sodium ion transport	15/1884	85/18670	0.0222	0.4652	0.4474	FXYD3/P2RX7/SCN1B/SLC9A1/SCN3B/AHCYL1/AKT1/SLC9A3R1/ANK3/CAV3/COMMD1/ACTN4/FXYD2/ARF1/WNK2	15
BP	GO:0060142	regulation of syncytium formation by plasma membrane fusion	7/1884	29/18670	0.02252	0.4653	0.4475	CAPN2/TNFSF14/EHD1/CAMK1/RAPGEF3/MYF6/MYF5	7
BP	GO:0031295	T cell costimulation	11/1884	56/18670	0.02259	0.4653	0.4475	CAV1/TNFSF14/AKT1/LCK/FYN/TMIGD2/PIK3R1/DPP4/PDCD1LG2/CDC42/PAK3	11
BP	GO:0002686	negative regulation of leukocyte migration	10/1884	49/18670	0.0226	0.4653	0.4475	PLCB1/HMOX1/BCR/AKT1/NBL1/PTGER4/IL27RA/CYP19A1/PADI2/SLAMF8	10
BP	GO:0045010	actin nucleation	10/1884	49/18670	0.0226	0.4653	0.4475	ARPC2/FCHSD2/FMN2/IQGAP2/WHAMMP3/WASF1/WAS/LMOD3/ARF1/PICK1	10
BP	GO:0071825	protein-lipid complex subunit organization	10/1884	49/18670	0.0226	0.4653	0.4475	BIN1/LIPG/APOA5/DGAT1/LCAT/APOC1/APOC3/PLAGL2/PRKACA/ARF1	10
BP	GO:0035637	multicellular organismal signaling	30/1884	204/18670	0.02277	0.4665	0.4487	FXYD3/BIN1/CAV1/SCN1B/SLC9A1/ATP2A2/SCN3B/AHCYL1/CACNB1/AVPR1A/YWHAE/KCNK15/NFASC/STIM1/ANK3/CNTNAP2/KCNK3/CACNA2D1/SCN9A/ASPH/PRKACA/P2RX3/NTRK3/TRDN/CACNB2/NPPA/RYR3/CACNG7/FXYD2/GJA1	30
BP	GO:0030322	stabilization of membrane potential	5/1884	17/18670	0.02289	0.4665	0.4487	KCNK7/KCNK15/KCNK17/KCNK3/KCNK12	5
BP	GO:0070166	enamel mineralization	5/1884	17/18670	0.02289	0.4665	0.4487	TCIRG1/STIM1/AMTN/CNNM4/FAM20C	5
BP	GO:0006661	phosphatidylinositol biosynthetic process	19/1884	116/18670	0.02314	0.4699	0.452	PGAP3/PIGV/PIP5K1C/CDS1/PLEKHA4/PIK3CG/ZP3/PIK3R1/BMX/DPM3/PIGO/PIGA/INPP4B/SACM1L/PIK3CB/CDIPT/PTPN13/PIK3R3/ARF1	19
BP	GO:1903313	positive regulation of mRNA metabolic process	14/1884	78/18670	0.02322	0.4699	0.452	HMX2/NANOS3/CNOT1/STH/RBM24/CELF3/TOB1/ROCK1/PLEKHN1/THRAP3/KHSRP/CIRBP/PRR5L/CNOT6L	14
BP	GO:0032959	inositol trisphosphate biosynthetic process	6/1884	23/18670	0.02346	0.4701	0.4521	PLCB1/PLCB3/HRH1/PLCB4/PLCG1/PLCL1	6
BP	GO:0086012	membrane depolarization during cardiac muscle cell action potential	6/1884	23/18670	0.02346	0.4701	0.4521	SCN1B/SCN3B/ANK3/CAV3/CACNA2D1/CACNB2	6
BP	GO:1903861	positive regulation of dendrite extension	6/1884	23/18670	0.02346	0.4701	0.4521	CPNE5/SMURF1/RIMS2/SYT4/UNC13A/CACNG7	6
BP	GO:1903522	regulation of blood circulation	41/1884	297/18670	0.02402	0.4796	0.4612	FXYD3/AGER/BIN1/MYL3/CAV1/HBEGF/SCN1B/SLC9A1/ATP2A2/SCN3B/AHCYL1/CACNB1/AVPR1A/YWHAE/ECE1/AKT1/KCNK15/STIM1/HRH1/PIK3CG/DOCK4/CAV3/TH/HRH2/KCNK3/CACNA2D1/NPFF/PDE5A/LEP/ASPH/PRKACA/DOCK5/TRDN/CACNB2/NPPA/RYR3/CACNG7/EDN2/FXYD2/GJA1/CHGA	41
BP	GO:0045765	regulation of angiogenesis	51/1884	383/18670	0.0243	0.4813	0.4629	RHOJ/MIR193A/HDAC5/ITGB1BP1/HTATIP2/MAP2K5/HMOX1/MIR106B/ECM1/COL4A2/AKT3/PPARG/RAMP2/DCN/DLL4/PGK1/PTGIS/JAK1/STIM1/MIR185/KLF2/SYNJ2BP/THBS4/PRL/CCR3/TMIGD2/GDF2/CD34/MIR212/ITGB2/MIR497/ROCK1/PROK2/PGF/TSPAN12/MIRLET7B/PLCG1/STARD13/RAPGEF3/PRKD1/LEP/RLN2/BMPER/HSPG2/GPNMB/MIR99B/AMOT/PRKCB/MIR329-1/CTSH/PLXND1	51
BP	GO:0034314	Arp2/3 complex-mediated actin nucleation	8/1884	36/18670	0.02456	0.4813	0.4629	ARPC2/FCHSD2/IQGAP2/WHAMMP3/WASF1/WAS/ARF1/PICK1	8
BP	GO:0090218	positive regulation of lipid kinase activity	8/1884	36/18670	0.02456	0.4813	0.4629	FGFR3/PDGFRB/PTK2/DGKZ/AMBRA1/PRKD1/VAV2/FLT3	8
BP	GO:1901099	negative regulation of signal transduction in absence of ligand	8/1884	36/18670	0.02456	0.4813	0.4629	MAP2K5/EYA4/AKT1/RIPK1/C8orf44-SGK3/FYN/MCL1/EYA2	8
BP	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	8/1884	36/18670	0.02456	0.4813	0.4629	MAP2K5/EYA4/AKT1/RIPK1/C8orf44-SGK3/FYN/MCL1/EYA2	8
BP	GO:0051648	vesicle localization	42/1884	306/18670	0.02461	0.4813	0.4629	SYT8/P2RX7/TRAK2/TRAPPC3/TRIM46/ATP2A2/PIP5K1C/PEF1/VPS18/SEC16B/CAMK2A/STXBP5L/KIF1B/PPP6R3/PREPL/COL7A1/PIK3CG/CTSC/SNAP25/AP3D1/MREG/FOLR1/MAP2/ADORA2A/TRAK1/ARL6/EXOC4/SYT12/RIMS2/PCLO/CACNB2/SYT4/KIAA1107/KIF3A/PRKCB/RIMS3/UNC13A/ACTN4/DCTN2/GRIA1/MLPH/ARF1	42
BP	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	47/1884	349/18670	0.02484	0.4813	0.4629	DLX5/LTBP2/CAV1/SKOR1/ADAMTSL2/PRDM16/TMEM100/CREB1/DAB2/VASN/PTK2/ITGA3/SKIL/NBL1/GDF7/EGR1/CAV3/LNPEP/TGFB1I1/FURIN/GDF2/SMURF1/CD109/CBL/FOLR1/MAPK3/MIR212/TOB1/ARRB2/STRAP/TGFBR3/ZBTB7A/TGFBR1/MSTN/SLC33A1/ZC3H3/NKX2-1/BMPER/SOST/SUB1/FOS/HTRA1/SMAD2/SMPD3/ING2/ITGB5/FZD1	47
BP	GO:0046394	carboxylic acid biosynthetic process	60/1884	462/18670	0.02492	0.4813	0.4629	SLC4A1/PYCR2/P2RX7/GPX4/ADIPOQ/ALOX15B/TECR/PTGES2/GPD1/NUP153/AVPR1A/DCN/LIPG/PGK1/GALK1/CBS/ACADVL/APOA5/PTGIS/ABAT/ASS1/ACSS1/ELOVL3/CYP46A1/OSBP/MIR185/FOXK1/GCKR/HSD3B7/ACOT12/GAPDHS/CSPG4/AMACR/APOC1/ZBTB7A/APOC3/GLUD2/BHMT/ACOT11/NUP85/MGST2/CARNS1/ACOX2/TREX1/PFKP/PROX1/PLP1/EGF/CD74/EDN2/GPT/PRKAG3/CLTC/SLC45A3/SRR/NUP35/AKR1C3/ACSS2/SMPD3/ALOX12B	60
BP	GO:0043550	regulation of lipid kinase activity	12/1884	64/18670	0.02495	0.4813	0.4629	FGFR3/PDGFRB/PTK2/DGKZ/PIK3IP1/AMBRA1/PIK3R1/PRKD1/VAV2/PIK3R3/FLT3/SOCS2	12
BP	GO:0003018	vascular process in circulatory system	26/1884	173/18670	0.02533	0.4813	0.4629	ITGB1BP1/CAV1/HMOX1/UTS2R/RAMP2/BCR/AVPR1A/ECE1/P2RY2/AKT1/HRH1/ANGPT1/DOCK4/HRH2/ROCK1/ARHGAP35/ADORA2A/HTR1D/ATG5/LEP/DOCK5/NPPA/EDN2/GJA1/CHGA/GRIP2	26
BP	GO:0031294	lymphocyte costimulation	11/1884	57/18670	0.02553	0.4813	0.4629	CAV1/TNFSF14/AKT1/LCK/FYN/TMIGD2/PIK3R1/DPP4/PDCD1LG2/CDC42/PAK3	11
BP	GO:0030866	cortical actin cytoskeleton organization	9/1884	43/18670	0.02553	0.4813	0.4629	WIPF3/FMNL2/FMNL3/RHOQ/ROCK1/PDCD6IP/ECT2/WIPF2/WAS	9
BP	GO:0034383	low-density lipoprotein particle clearance	9/1884	43/18670	0.02553	0.4813	0.4629	ADIPOQ/HMOX1/MIR185/NPC2/EHD1/AP2A2/APOC3/KHSRP/CLTC	9
BP	GO:0045746	negative regulation of Notch signaling pathway	9/1884	43/18670	0.02553	0.4813	0.4629	MMP14/TSPAN15/DLL4/AKT1/NRARP/ZBTB7A/LFNG/ARRB1/EGF	9
BP	GO:0071260	cellular response to mechanical stimulus	14/1884	79/18670	0.02569	0.4813	0.4629	PIEZO1/SLC9A1/TNFSF14/AKT1/SLC2A1/PTGER4/TLR8/MAP3K14/COL1A1/MAPK3/MAP3K1/NPPA/GJA1/TNFRSF1A	14
BP	GO:0014074	response to purine-containing compound	23/1884	149/18670	0.02572	0.4813	0.4629	P2RX7/PTPRN/ADIPOQ/GPD1/PPARG/P2RY2/AANAT/ASS1/PIK3CG/COL1A1/WT1/JUNB/ADORA2A/RAPGEF1/ALDH3A1/MMP19/RAPGEF3/P2RX3/P2RX5/FOS/RYR3/TAF1/CFTR	23
BP	GO:0009409	response to cold	10/1884	50/18670	0.02578	0.4813	0.4629	METRNL/SLC9A1/PPARG/ACADVL/TMEM135/TRPM8/ACOT11/P2RX3/CIRBP/FOS	10
BP	GO:0034330	cell junction organization	40/1884	290/18670	0.02585	0.4813	0.4629	MMP14/ARVCF/ITGB1BP1/CAV1/TNS1/IQSEC1/SLC9A1/ITGA6/PIP5K1C/RAMP2/ACTG1/CD9/BCR/GPBAR1/PTK2/ARHGEF7/ACTN1/DLC1/NFASC/EPHA3/CORO2B/PECAM1/ROCK1/PDCD6IP/TBCD/ECT2/TGFBR1/LAMA3/RAPGEF1/THY1/CSF1R/PRKACA/FBLIM1/NUMBL/ACTN4/PKP1/GJA1/CDC42/CD177/RCC2	40
BP	GO:0016053	organic acid biosynthetic process	60/1884	463/18670	0.02591	0.4813	0.4629	SLC4A1/PYCR2/P2RX7/GPX4/ADIPOQ/ALOX15B/TECR/PTGES2/GPD1/NUP153/AVPR1A/DCN/LIPG/PGK1/GALK1/CBS/ACADVL/APOA5/PTGIS/ABAT/ASS1/ACSS1/ELOVL3/CYP46A1/OSBP/MIR185/FOXK1/GCKR/HSD3B7/ACOT12/GAPDHS/CSPG4/AMACR/APOC1/ZBTB7A/APOC3/GLUD2/BHMT/ACOT11/NUP85/MGST2/CARNS1/ACOX2/TREX1/PFKP/PROX1/PLP1/EGF/CD74/EDN2/GPT/PRKAG3/CLTC/SLC45A3/SRR/NUP35/AKR1C3/ACSS2/SMPD3/ALOX12B	60
BP	GO:0003334	keratinocyte development	4/1884	12/18670	0.02638	0.4813	0.4629	FLNB/FOSL2/CDSN/IFT74	4
BP	GO:0006069	ethanol oxidation	4/1884	12/18670	0.02638	0.4813	0.4629	ACSS1/ADH7/ACSS2/ADH1B	4
BP	GO:0010452	histone H3-K36 methylation	4/1884	12/18670	0.02638	0.4813	0.4629	SETMAR/IWS1/BCOR/SMYD2	4
BP	GO:0010896	regulation of triglyceride catabolic process	4/1884	12/18670	0.02638	0.4813	0.4629	APOA5/PIK3CG/APOC3/PNPLA2	4
BP	GO:0032252	secretory granule localization	4/1884	12/18670	0.02638	0.4813	0.4629	TRIM46/KIF1B/PIK3CG/MAP2	4
BP	GO:0032905	transforming growth factor beta1 production	4/1884	12/18670	0.02638	0.4813	0.4629	LUM/FURIN/SERPINB7/CD2AP	4
BP	GO:0034372	very-low-density lipoprotein particle remodeling	4/1884	12/18670	0.02638	0.4813	0.4629	LIPG/APOA5/LCAT/APOC3	4
BP	GO:0045080	positive regulation of chemokine biosynthetic process	4/1884	12/18670	0.02638	0.4813	0.4629	AGER/HMOX1/EGR1/CD74	4
BP	GO:1902287	semaphorin-plexin signaling pathway involved in axon guidance	4/1884	12/18670	0.02638	0.4813	0.4629	PLXNC1/PLXNB2/PLXNA2/PLXND1	4
BP	GO:0010810	regulation of cell-substrate adhesion	31/1884	215/18670	0.02676	0.4849	0.4663	MMP14/ITGB1BP1/NID1/SLC9A1/ARPC2/ITGA6/UNC13D/VIT/CSF1/PTK2/ARHGEF7/DLC1/ITGA3/COL1A1/EPHA3/CORO2B/PIK3R1/ROCK1/TBCD/MMRN1/POSTN/THY1/FBLN1/ATXN3/DOCK5/PIK3CB/ACTN4/CDC42/MYF5/RCC2/SPOCK2	31
BP	GO:0006024	glycosaminoglycan biosynthetic process	18/1884	110/18670	0.02679	0.4849	0.4663	EXT2/LUM/CHST2/PDGFRB/CHST3/DCN/EXTL1/ANGPT1/ST3GAL3/PRELP/CSPG4/CHST1/B4GALT2/HSPG2/EGF/CLTC/SMPD3/EXT1	18
BP	GO:0010959	regulation of metal ion transport	52/1884	394/18670	0.02682	0.4849	0.4663	FXYD3/CAMK2G/SESTD1/BIN1/CAV1/P2RX7/BEST1/SCN1B/SLC9A1/KCNS1/SCN3B/AHCYL1/CACNB1/RCVRN/PDGFRB/CAMK2A/YWHAE/TRPV3/AKT1/SLC9A3R1/F2RL3/CAB39/STIM1/PIK3CG/FYN/STAC2/ANK3/STC2/LGALS3/CAV3/COMMD1/MIR212/ARRB2/CACNA2D1/ADORA2A/PLCG1/THY1/ATG5/PRKACA/P2RX3/P2RX5/TRDN/CACNB2/NPPA/EGF/GRIN3B/AHNAK/ACTN4/FXYD2/GJA1/ARF1/WNK2	52
BP	GO:0018107	peptidyl-threonine phosphorylation	20/1884	126/18670	0.02745	0.4943	0.4754	VRK2/CSNK2A1/CDC42BPB/CAMK2A/AKT1/CAB39/CSNK1G2/CDK10/CSNK1A1/CLK1/ROCK1/TGFBR1/PRKD1/TNKS/EIF4G1/PRKACA/EGF/PRKCB/TAF1/CDC42BPA	20
BP	GO:0018210	peptidyl-threonine modification	21/1884	134/18670	0.02759	0.4943	0.4754	VRK2/CSNK2A1/CDC42BPB/CAMK2A/AKT1/CAB39/CSNK1G2/CDK10/CSNK1A1/CLK1/ROCK1/TGFBR1/PRKD1/TNKS/EIF4G1/PRKACA/EGF/PRKCB/TAF1/CDC42BPA/GALNT13	21
BP	GO:0045926	negative regulation of growth	35/1884	249/18670	0.02759	0.4943	0.4754	WNT3/FGFR3/WWC2/TRIM46/TNK1/RBP4/ALOX15B/SERTAD2/GNG4/SERTAD3/PPARG/CDKN1A/RIPK1/PTK2/SEMA3D/CCDC85B/STC2/WT1/CAV3/GDF2/SPP1/SEMA4C/MAP2/SEMA3G/MSTN/LGMN/APBB1/PPT1/NPPA/PI16/DCC/SOCS2/GJA1/PTK6/RTN4R	35
BP	GO:0046883	regulation of hormone secretion	37/1884	266/18670	0.02777	0.4956	0.4766	OXCT1/ADIPOQ/RBP4/MIDN/CREB1/HCAR2/STXBP5L/TCIRG1/SLC2A1/ABAT/RAB11FIP5/ADCY5/SNAP25/NADK/KCNS3/SPP1/NNAT/ADORA2A/NPFF/ILDR1/RAPGEF3/LEP/TCF7L2/NEUROD1/ARRB1/SCT/CYP19A1/DPP4/LRP5/NPPA/GNAS/POMC/NKX3-1/GJA1/SLC9B2/CHGA/CFTR	37
BP	GO:0051258	protein polymerization	39/1884	283/18670	0.02783	0.4956	0.4766	TMOD4/BIN1/CCL26/GPX4/NCK2/SLAIN2/RHOBTB2/ARPC2/FER/PYCARD/CDC42EP2/FCHSD2/CORO7/SPTBN5/NIN/BAIAP2/TMOD3/C15orf62/FBXO5/CAV3/BAIAP2L2/TBCD/MAP2/FHOD3/VILL/NAV3/FMN2/ARL6/CDC42EP5/IQGAP2/WHAMMP3/CAPZA3/WASF1/WAS/LMOD3/ARF1/PICK1/PAK3/CAMSAP1	39
BP	GO:0032091	negative regulation of protein binding	17/1884	103/18670	0.02855	0.4971	0.4781	BAG2/ITGB1BP1/CAV1/ADIPOQ/DAB2/AKT1/PTPRF/PPP1CA/MAPK3/ARRB2/ROCK1/MAP2/SLPI/CAMK1/XIRP1/CARD18/NKX3-1	17
BP	GO:0030212	hyaluronan metabolic process	8/1884	37/18670	0.02865	0.4971	0.4781	SLC9A1/AKT1/LYVE1/EGF/PIM1/CLTC/ITIH4/SMPD3	8
BP	GO:0034405	response to fluid shear stress	8/1884	37/18670	0.02865	0.4971	0.4781	P2RX7/MAP2K5/PDGFRB/AKT1/ASS1/KLF2/HDAC3/GJA1	8
BP	GO:1903427	negative regulation of reactive oxygen species biosynthetic process	8/1884	37/18670	0.02865	0.4971	0.4781	CAV1/PTGIS/MIR181A2/FYN/SIRPA/CD34/MIR212/KHSRP	8
BP	GO:2000249	regulation of actin cytoskeleton reorganization	8/1884	37/18670	0.02865	0.4971	0.4781	BAIAP2/BAIAP2L2/RAPGEF3/CD2AP/CSF1R/NTRK3/CDC42/NTF3	8
BP	GO:0002092	positive regulation of receptor internalization	6/1884	24/18670	0.02869	0.4971	0.4781	ANGPT1/ARRB2/ARRB1/EGF/PICK1/NTF3	6
BP	GO:1901071	glucosamine-containing compound metabolic process	6/1884	24/18670	0.02869	0.4971	0.4781	MGAT3/CHST2/CHST3/GNE/CHST1/CHST4	6
BP	GO:0019229	regulation of vasoconstriction	11/1884	58/18670	0.02873	0.4971	0.4781	CAV1/AVPR1A/ECE1/AKT1/HRH1/DOCK4/HRH2/LEP/DOCK5/EDN2/GJA1	11
BP	GO:0032722	positive regulation of chemokine production	11/1884	58/18670	0.02873	0.4971	0.4781	AGER/HAVCR2/ADIPOQ/HMOX1/ALOX15B/PYCARD/EGR1/IL1RL1/POSTN/CSF1R/CD74	11
BP	GO:0120032	regulation of plasma membrane bounded cell projection assembly	26/1884	175/18670	0.0288	0.4971	0.4781	CAV1/P2RX7/ARPC2/EPS8L3/FER/RHOQ/CDC42EP2/C15orf62/CDK10/ARHGAP35/TGFBR1/TCTEX1D2/MSTN/ZMYND10/ATG5/TBC1D30/RAP1GAP/WRAP73/CDC42EP5/PLEKHM1/WAS/CDC42/WASF2/ZMYND8/CDKL1/RCC2	26
BP	GO:0051957	positive regulation of amino acid transport	5/1884	18/18670	0.02913	0.4971	0.4781	P2RX7/AVPR1A/ABAT/ADORA2A/SYT4	5
BP	GO:0071318	cellular response to ATP	5/1884	18/18670	0.02913	0.4971	0.4781	P2RX7/P2RY2/P2RX3/RYR3/TAF1	5
BP	GO:0090196	regulation of chemokine secretion	5/1884	18/18670	0.02913	0.4971	0.4781	ALOX15B/PYCARD/IL1RL1/POSTN/CSF1R	5
BP	GO:0048608	reproductive structure development	56/1884	431/18670	0.02919	0.4971	0.4781	MMP14/PTPRN/PCDH12/RXRA/RBP4/ALOX15B/FOXF2/PPARG/CRIP1/PDGFRB/LHX4/DCN/AKT1/TYRO3/PTGIS/PTK2/GDF7/STC2/WT1/ZP3/JUNB/CBL/MAPK3/GJB3/SPP1/ARRB2/FEM1B/GAS2/TCF23/TGFBR1/TNFSF10/MMP19/WDR19/ZFPM2/NR0B1/ST14/LEP/LFNG/NKX2-1/BCL2L2/ARRB1/DLX3/RHOBTB3/CYP19A1/FANCG/VDR/HTRA1/TAF4/SERPINB5/RAD21L1/NKX3-1/GJA1/AKR1C3/TIFAB/ING2/NR5A1	56
BP	GO:0001649	osteoblast differentiation	32/1884	225/18670	0.02938	0.4971	0.4781	DLX5/LIMD1/WNT3/IFT80/MRC2/MEF2D/ZHX3/TCIRG1/RRAS2/AKT1/PTK2/SH3PXD2B/COL1A1/FBXO5/JUNB/GDF2/MIR200C/TOB1/SPP1/PRKD1/SYNCRIP/MIR675/PRKACA/BCAP29/CLEC5A/GPNMB/LRP5/GNAS/CLTC/FAM20C/GJA1/FZD1	32
BP	GO:0007173	epidermal growth factor receptor signaling pathway	19/1884	119/18670	0.0294	0.4971	0.4781	RHBDF1/STAM2/HBEGF/NCK2/ERRFI1/FER/AKT1/PTK2/ARHGEF7/RHBDF2/GPRC5A/HIP1/PIK3R1/CBL/PLCG1/STAM/EGF/CDC42/PTK6	19
BP	GO:0045921	positive regulation of exocytosis	15/1884	88/18670	0.02951	0.4971	0.4781	UNC13D/AP1G1/ZP3/ITGB2/PDCD6IP/LAMP1/STAM/CACNB2/NPPA/SYT4/SCAMP5/SMPD3/ARF1/CD177/CFTR	15
BP	GO:0035296	regulation of tube diameter	22/1884	143/18670	0.02965	0.4971	0.4781	ITGB1BP1/CAV1/HMOX1/UTS2R/AVPR1A/ECE1/P2RY2/AKT1/HRH1/DOCK4/HRH2/ROCK1/ADORA2A/HTR1D/ATG5/LEP/DOCK5/NPPA/EDN2/GJA1/CHGA/GRIP2	22
BP	GO:0050880	regulation of blood vessel size	22/1884	143/18670	0.02965	0.4971	0.4781	ITGB1BP1/CAV1/HMOX1/UTS2R/AVPR1A/ECE1/P2RY2/AKT1/HRH1/DOCK4/HRH2/ROCK1/ADORA2A/HTR1D/ATG5/LEP/DOCK5/NPPA/EDN2/GJA1/CHGA/GRIP2	22
BP	GO:0097746	regulation of blood vessel diameter	22/1884	143/18670	0.02965	0.4971	0.4781	ITGB1BP1/CAV1/HMOX1/UTS2R/AVPR1A/ECE1/P2RY2/AKT1/HRH1/DOCK4/HRH2/ROCK1/ADORA2A/HTR1D/ATG5/LEP/DOCK5/NPPA/EDN2/GJA1/CHGA/GRIP2	22
BP	GO:0043484	regulation of RNA splicing	21/1884	135/18670	0.02968	0.4971	0.4781	HMX2/KHDRBS3/KHDRBS1/PTBP2/STH/RBM24/CELF3/ESRP1/SRSF9/RBM17/CELF1/RPS26/PIK3R1/RBFOX3/CLK1/ZBTB7A/THRAP3/SRPK2/CIRBP/ERN1/AHNAK	21
BP	GO:0043393	regulation of protein binding	31/1884	217/18670	0.02997	0.5006	0.4814	BAG2/HDAC5/PRMT7/ITGB1BP1/CAV1/NMD3/ADIPOQ/DAB2/AKT1/PTPRF/ANGPT1/PPP1CA/LGALS3/MAPK3/ARRB2/ROCK1/TGFBR3/MAP2/TGFBR1/SLPI/CAMK1/TCF7L2/LFNG/PLCL1/PRKACA/ARRB1/XIRP1/CARD18/NKX3-1/TAF1/PLXND1	31
BP	GO:0006650	glycerophospholipid metabolic process	43/1884	319/18670	0.03031	0.5035	0.4842	PLA2G4B/TTC7A/PLA2G12A/PGAP3/PLCB1/PIGV/IP6K3/AGPAT4/PIP5K1C/GPD1/CSNK2A1/PDGFRB/CAPN2/CDS1/OSBPL10/PLEKHA4/APOA5/MFSD2A/AGPAT3/DGKZ/LCAT/PIK3CG/OSBPL5/ZP3/PIK3R1/GDPD3/APOC1/LPCAT1/BMX/DPM3/THEM5/PIGO/CSF1R/PIGA/INPP4B/SACM1L/PIK3CB/CDIPT/PTPN13/PIK3R3/SOCS2/INPP5A/ARF1	43
BP	GO:0018205	peptidyl-lysine modification	52/1884	397/18670	0.03034	0.5035	0.4842	CAMKMT/CRTC2/DMAP1/ZMIZ2/PRDM16/SETMAR/SUMO2/LOXL2/NUP153/IWS1/LMNA/DOT1L/RNF212/TET3/EGR1/SUPT6H/CTCF/KAT7/BCOR/SMYD2/CPA4/ACTL6B/MAPK3/SETD7/TOLLIP/CBX4/NNAT/SUV39H2/TAF5L/YEATS4/RASD2/ATG5/NUP85/KAT6B/DOHH/PRDM7/ARRB1/APBB1/NSMCE2/SETD1A/PHF10/PHF19/PIAS4/TAF1/CTBP1/NUP35/EPC1/HMG20A/WDR82/NAA40/EGR2/ZMIZ1	52
BP	GO:0048010	vascular endothelial growth factor receptor signaling pathway	16/1884	96/18670	0.0304	0.5035	0.4842	NCK2/PTK2/BAIAP2/FYN/MAPKAPK3/PIK3R1/ROCK1/PGF/NCF2/PRKD1/MYOF/VAV2/PIK3CB/PRKCB/CDC42/WASF2	16
BP	GO:0009408	response to heat	26/1884	176/18670	0.03066	0.5065	0.4871	BAG2/CAMK2G/SCARA5/HMOX1/ATP2A2/CDKN1A/NUP153/CAMK2A/YWHAE/TRPV3/AKT1/TGFB1I1/CD34/MAPK3/CETN1/ARPP21/MSTN/NUP85/MYOF/DNAJB1/ATXN3/PRKACA/P2RX3/DNAJA1/POLR2D/NUP35	26
BP	GO:0045428	regulation of nitric oxide biosynthetic process	12/1884	66/18670	0.03106	0.5117	0.4921	CAV1/AKT1/PTGIS/ASS1/KLF2/MIR181A2/SIRPA/CD34/MIR212/ITGB2/KHSRP/MIR99B	12
BP	GO:0043405	regulation of MAP kinase activity	45/1884	337/18670	0.03136	0.5123	0.4927	NEK10/AGER/DUSP8/CAV1/P2RX7/ADIPOQ/MAP2K5/BIRC7/MADD/PDGFRB/NOD1/TNIK/RIPK1/ALK/GPS2/SPRY4/MAP3K6/ELANE/GHR/RET/MAP3K14/PIK3CG/MAPKAPK3/CAV3/CSPG4/MAPK3/AKAP13/PROK2/TGFBR1/TAB3/RAPGEF1/PDE5A/ARRB1/PIK3CB/NTRK3/ERN1/MAP3K1/EGF/DNAJA1/CD74/FLT3/PAK3/FGD2/FPR1/NTF3	45
BP	GO:0072659	protein localization to plasma membrane	36/1884	260/18670	0.03147	0.5123	0.4927	MMP14/SLC4A1/TTC7A/RAB31/ARHGEF16/ITGB1BP1/ADIPOQ/LRRC7/SCN3B/DAB2/RAMP2/TSPAN15/TNIK/RHOQ/AKT1/SLC9A3R1/NFASC/ITGA3/PREPL/STAC2/ANK3/LGALS3/EPHA3/CAV3/PIK3R1/SMURF1/PPFIA1/RAPGEF6/ROCK1/GPR158/ARL6/CACNB2/CLTC/LYPD1/TNFRSF1A/GRIP2	36
BP	GO:0001938	positive regulation of endothelial cell proliferation	18/1884	112/18670	0.03148	0.5123	0.4927	CCL26/HMOX1/ECM1/AKT3/AKT1/STAT5A/THBS4/CCR3/GDF2/NRARP/PGF/MIRLET7B/TGFBR1/PLCG1/PRKD1/NR4A1/PROX1/SCG2	18
BP	GO:0014902	myotube differentiation	18/1884	112/18670	0.03148	0.5123	0.4927	MMP14/HDAC5/SORT1/CD9/NLN/AVPR1A/CAPN2/RBM24/TNFSF14/EHD1/XK/CAV3/MYEF2/KCNH1/MYF6/MYOF/LMOD3/MYF5	18
BP	GO:0003014	renal system process	19/1884	120/18670	0.03175	0.5123	0.4927	SLC4A1/ADCY9/ADIPOQ/COMT/BCR/AVPR1A/SLC9A3R1/ITGA3/ADCY5/CORO2B/CD34/ADORA2A/SLC4A5/SGK1/ADCY4/LGMN/PRKACA/GJA1/AKR1C3	19
BP	GO:0035150	regulation of tube size	22/1884	144/18670	0.03178	0.5123	0.4927	ITGB1BP1/CAV1/HMOX1/UTS2R/AVPR1A/ECE1/P2RY2/AKT1/HRH1/DOCK4/HRH2/ROCK1/ADORA2A/HTR1D/ATG5/LEP/DOCK5/NPPA/EDN2/GJA1/CHGA/GRIP2	22
BP	GO:0034694	response to prostaglandin	7/1884	31/18670	0.0318	0.5123	0.4927	PPARG/AANAT/AKT1/PTGER4/TGFBR3/AKR1C2/AKR1C3	7
BP	GO:0002576	platelet degranulation	20/1884	128/18670	0.03188	0.5123	0.4927	ECM1/FERMT3/CLEC3B/CD9/CHID1/ACTN1/A2M/CTSW/CD109/VWF/PECAM1/SPP2/APLP2/MMRN1/ENDOD1/EGF/ACTN4/CFD/ITIH4/GTPBP2	20
BP	GO:0002687	positive regulation of leukocyte migration	20/1884	128/18670	0.03188	0.5123	0.4927	MMP14/AGER/PYCARD/DAPK2/CSF1/TNFSF14/ELANE/THBS4/ZP3/LGALS3/PLVAP/MAPK3/PGF/S100A14/THY1/MSTN/CXCL14/LGMN/CD74/EDN2	20
BP	GO:0008333	endosome to lysosome transport	11/1884	59/18670	0.03221	0.5137	0.4941	SNX27/BIN1/TRAK2/SORT1/VPS18/LYST/DENND3/AP3D1/RAB12/TRAK1/CACNG7	11
BP	GO:0033619	membrane protein proteolysis	11/1884	59/18670	0.03221	0.5137	0.4941	TIMP2/P2RX7/SNX33/SPPL2B/TIMP4/RET/FURIN/ROCK1/RHBDD1/APH1A/CTSH	11
BP	GO:0032602	chemokine production	15/1884	89/18670	0.0323	0.5137	0.4941	AGER/HAVCR2/ADIPOQ/MAP2K5/HMOX1/ALOX15B/PYCARD/ELANE/EGR1/SIRPA/IL1RL1/POSTN/CSF1R/S100A9/CD74	15
BP	GO:0060491	regulation of cell projection assembly	26/1884	177/18670	0.03261	0.5137	0.4941	CAV1/P2RX7/ARPC2/EPS8L3/FER/RHOQ/CDC42EP2/C15orf62/CDK10/ARHGAP35/TGFBR1/TCTEX1D2/MSTN/ZMYND10/ATG5/TBC1D30/RAP1GAP/WRAP73/CDC42EP5/PLEKHM1/WAS/CDC42/WASF2/ZMYND8/CDKL1/RCC2	26
BP	GO:0050673	epithelial cell proliferation	56/1884	434/18670	0.03279	0.5137	0.4941	DLX5/DLX6/MIR193A/MMP14/IFT80/CCL26/ITGB1BP1/CAV1/PTPRN/MAP2K5/HMOX1/ERRFI1/ECM1/AKT3/LOXL2/PPARG/FOXE3/DLL4/AKT1/IFT74/STAT5A/SYNJ2BP/THBS4/PRL/CCR3/GDF2/IFT122/CD109/CD34/STRAP/MIR497/TGFBR3/NRARP/PGF/MIRLET7B/TGFBR1/PLCG1/IGFBP4/PAX6/PRKD1/LEP/TCF7L2/BCL2L2/BMPER/PIK3CB/ERN1/NR4A1/PROX1/VDR/HTRA1/MYC/SERPINB5/NKX3-1/MIR329-1/GJA1/SCG2	56
BP	GO:0061458	reproductive system development	56/1884	434/18670	0.03279	0.5137	0.4941	MMP14/PTPRN/PCDH12/RXRA/RBP4/ALOX15B/FOXF2/PPARG/CRIP1/PDGFRB/LHX4/DCN/AKT1/TYRO3/PTGIS/PTK2/GDF7/STC2/WT1/ZP3/JUNB/CBL/MAPK3/GJB3/SPP1/ARRB2/FEM1B/GAS2/TCF23/TGFBR1/TNFSF10/MMP19/WDR19/ZFPM2/NR0B1/ST14/LEP/LFNG/NKX2-1/BCL2L2/ARRB1/DLX3/RHOBTB3/CYP19A1/FANCG/VDR/HTRA1/TAF4/SERPINB5/RAD21L1/NKX3-1/GJA1/AKR1C3/TIFAB/ING2/NR5A1	56
BP	GO:0070373	negative regulation of ERK1 and ERK2 cascade	13/1884	74/18670	0.03288	0.5137	0.4941	ITGB1BP1/ADIPOQ/ERRFI1/SLC9A3R1/SPRY4/MIR185/SYNJ2BP/SIRPA/CAMK2N1/RAPGEF1/FBLN1/ARRB1/WNK2	13
BP	GO:2000649	regulation of sodium ion transmembrane transporter activity	10/1884	52/18670	0.03307	0.5137	0.4941	FXYD3/SCN1B/SLC9A1/SCN3B/SLC9A3R1/ANK3/CAV3/ACTN4/FXYD2/WNK2	10
BP	GO:0007044	cell-substrate junction assembly	16/1884	97/18670	0.03312	0.5137	0.4941	MMP14/ITGB1BP1/TNS1/SLC9A1/ITGA6/BCR/PTK2/ARHGEF7/ACTN1/DLC1/EPHA3/CORO2B/ROCK1/LAMA3/THY1/RCC2	16
BP	GO:0030316	osteoclast differentiation	16/1884	97/18670	0.03312	0.5137	0.4941	MITF/TOB2/CREB1/CSF1/TCIRG1/PIK3R1/GPR183/JUNB/CD109/IL12B/CSF1R/FOS/GNAS/FAM20C/SLC9B2/KLF10	16
BP	GO:0046825	regulation of protein export from nucleus	8/1884	38/18670	0.03319	0.5137	0.4941	YWHAE/IWS1/SUPT6H/CAMK1/RAPGEF3/TCF7L2/PRKACA/PTPN14	8
BP	GO:0048638	regulation of developmental growth	46/1884	347/18670	0.03325	0.5137	0.4941	WNT3/FGFR3/WWC2/PLCB1/TRIM46/RBP4/CREB1/CDKN1A/CSF1/RUFY3/AKT1/RIPK1/STAT5A/PTK2/CPNE5/SEMA3D/SH3PXD2B/GHR/PRL/STC2/WT1/ZP3/CAV3/SMURF1/SPP1/SEMA4C/TGFBR3/MAP2/TGFBR1/SEMA3G/ZFPM2/MSTN/LEP/LGMN/NTRK3/RIMS2/PROX1/SYT4/PIM1/PI16/UNC13A/CACNG7/DCC/SOCS2/GJA1/RTN4R	46
BP	GO:0007584	response to nutrient	31/1884	219/18670	0.03346	0.5137	0.4941	OXCT1/P2RX7/KANK2/ADIPOQ/HMOX1/CREB1/PPARG/LIPG/P2RY2/ASS1/BAIAP2/PDK2/CYP26A1/FYN/COL1A1/STC2/FOLR1/SPP1/SERPINC1/POSTN/ALDH3A1/TNKS/LEP/P2RX3/P2RX5/ACSL1/VDR/RYR3/PIM1/TAF1/AKR1C3	31
BP	GO:0043583	ear development	31/1884	219/18670	0.03346	0.5137	0.4941	HMX3/HMX2/DLX5/DLX6/RPGRIP1L/FAT4/C1QTNF5/BCR/PDGFRB/ECE1/ESRP1/SLC9A3R1/TTC39C/MAPK3/KCNK3/LRIG3/POU3F4/USH1G/PRKRA/WDR19/ATG5/LRIG1/CXCL14/NEUROD1/BMPER/NTRK3/FZD2/PROX1/TPRN/TMIE/TIFAB	31
BP	GO:0071827	plasma lipoprotein particle organization	9/1884	45/18670	0.03348	0.5137	0.4941	LIPG/APOA5/DGAT1/LCAT/APOC1/APOC3/PLAGL2/PRKACA/ARF1	9
BP	GO:0060326	cell chemotaxis	41/1884	304/18670	0.0335	0.5137	0.4941	ITGA9/ARHGEF16/CCL26/HBEGF/PIP5K1C/LYST/PDGFRB/DAPK2/CSF1/TNFSF14/NBL1/HRH1/THBS4/PIK3CG/CCR3/DOCK4/LGALS3/HSD3B7/GPR183/MAPK3/ITGB2/ARRB2/PGF/S100A14/MSTN/PRKD1/NUP85/CXCL14/LGMN/S100A9/NR4A1/CYP19A1/PADI2/CXCR3/CALCA/SFTPD/CD74/SLAMF8/EDN2/CHGA/SCG2	41
BP	GO:1903037	regulation of leukocyte cell-cell adhesion	41/1884	304/18670	0.0335	0.5137	0.4941	FGL2/AGER/CAV1/HAVCR2/CD276/NCK2/PYCARD/TNFSF14/AKT1/ZBTB7B/LCK/ASS1/ELANE/FYN/SIRPA/ZP3/LGALS3/TMIGD2/PIK3R1/AP3D1/JAK3/ITGB2/NRARP/ADORA2A/TARM1/MAD1L1/CD55/THY1/PDE5A/LEP/IL12B/GPNMB/DPP4/SFTPD/PDCD1LG2/CD74/RASAL3/CDC42/PAK3/FOXJ1/ZMIZ1	41
BP	GO:0008593	regulation of Notch signaling pathway	17/1884	105/18670	0.03368	0.5137	0.4941	MMP14/ITGB1BP1/TSPAN15/DLL4/AKT1/ELF3/SYNJ2BP/MIR212/GAS2/NRARP/ZBTB7A/POSTN/LFNG/CNTN6/ARRB1/EGF/ZMIZ1	17
BP	GO:0045807	positive regulation of endocytosis	23/1884	153/18670	0.03377	0.5137	0.4941	RAB31/SH3GL1/MFGE8/PYCARD/DAB2/PPARG/BCR/APOA5/ANGPT1/SIRPA/CAV3/HIP1/CBL/ARRB2/RAPGEF1/ARRB1/PPT1/EGF/SFTPD/ACTN4/ARF1/PICK1/NTF3	23
BP	GO:0032642	regulation of chemokine production	14/1884	82/18670	0.03426	0.5137	0.4941	AGER/HAVCR2/ADIPOQ/MAP2K5/HMOX1/ALOX15B/PYCARD/ELANE/EGR1/SIRPA/IL1RL1/POSTN/CSF1R/CD74	14
BP	GO:0043967	histone H4 acetylation	12/1884	67/18670	0.03449	0.5137	0.4941	DMAP1/IWS1/KAT7/ACTL6B/YEATS4/ATG5/KAT6B/ARRB1/APBB1/CTBP1/EPC1/NAA40	12
BP	GO:0072677	eosinophil migration	6/1884	25/18670	0.03462	0.5137	0.4941	CCL26/DAPK2/PTGER4/HRH1/LGALS3/SCG2	6
BP	GO:0097186	amelogenesis	6/1884	25/18670	0.03462	0.5137	0.4941	ITGA6/TCIRG1/STIM1/AMTN/CNNM4/FAM20C	6
BP	GO:1903859	regulation of dendrite extension	6/1884	25/18670	0.03462	0.5137	0.4941	CPNE5/SMURF1/RIMS2/SYT4/UNC13A/CACNG7	6
BP	GO:0015850	organic hydroxy compound transport	36/1884	262/18670	0.03476	0.5137	0.4941	SYT8/GRAMD1B/CAV1/ADIPOQ/RXRA/RBP4/PPARG/OSBPL10/LIPG/APOA5/ABAT/MIR33B/GPS2/SLC22A1/SYT15/OSBP/NPC2/LCAT/OSBPL5/SLC10A6/SPP1/APOC1/ADORA2A/APOC3/SLCO1B3/LEP/SYT12/CYP19A1/HRH3/SYT4/EGF/POMC/AQP7/CHGA/AKR1C1/CFTR	36
BP	GO:0031274	positive regulation of pseudopodium assembly	4/1884	13/18670	0.03512	0.5137	0.4941	CDC42EP2/C15orf62/CDC42EP5/CDC42	4
BP	GO:0035723	interleukin-15-mediated signaling pathway	4/1884	13/18670	0.03512	0.5137	0.4941	PLCB1/JAK1/STAT5A/JAK3	4
BP	GO:0038065	collagen-activated signaling pathway	4/1884	13/18670	0.03512	0.5137	0.4941	COL4A2/COL4A1/COL1A1/COL4A5	4
BP	GO:0043116	negative regulation of vascular permeability	4/1884	13/18670	0.03512	0.5137	0.4941	RAMP2/ANGPT1/ARHGAP35/ADORA2A	4
BP	GO:0046831	regulation of RNA export from nucleus	4/1884	13/18670	0.03512	0.5137	0.4941	KHDRBS1/NUP153/IWS1/SUPT6H	4
BP	GO:0051451	myoblast migration	4/1884	13/18670	0.03512	0.5137	0.4941	ITGB1BP1/THBS4/ROCK1/MSTN	4
BP	GO:0071350	cellular response to interleukin-15	4/1884	13/18670	0.03512	0.5137	0.4941	PLCB1/JAK1/STAT5A/JAK3	4
BP	GO:0071352	cellular response to interleukin-2	4/1884	13/18670	0.03512	0.5137	0.4941	JAK1/STAT5A/CDC5L/JAK3	4
BP	GO:1902285	semaphorin-plexin signaling pathway involved in neuron projection guidance	4/1884	13/18670	0.03512	0.5137	0.4941	PLXNC1/PLXNB2/PLXNA2/PLXND1	4
BP	GO:2000009	negative regulation of protein localization to cell surface	4/1884	13/18670	0.03512	0.5137	0.4941	SNX33/CAV3/COMMD1/TAX1BP3	4
BP	GO:2000194	regulation of female gonad development	4/1884	13/18670	0.03512	0.5137	0.4941	WT1/ZP3/ZFPM2/NR5A1	4
BP	GO:0006022	aminoglycan metabolic process	25/1884	170/18670	0.03517	0.5137	0.4941	EXT2/LUM/SLC9A1/CHST2/PDGFRB/CHST3/DCN/AKT1/EXTL1/ANGPT1/ST3GAL3/PRELP/CSPG4/CHST1/SGSH/LYVE1/B4GALT2/HSPG2/EGF/PIM1/CLTC/ITIH4/SMPD3/EXT1/SPOCK2	25
BP	GO:0009416	response to light stimulus	42/1884	314/18670	0.03566	0.5196	0.4997	CAMKMT/BEST1/PPP1CC/MSH6/CREB1/N4BP1/SAG/GNA11/CDKN1A/RCVRN/CRIP1/NPTN/CDS1/SYNGAP1/AANAT/AKT1/ELANE/HRH1/INO80/PPP1CA/MFAP4/PIK3R1/TH/HRH2/RHBDD1/LRRN4/SERPINB13/B4GALT2/IL12B/NDRG4/ARRB1/CIRBP/FOS/TREX1/MYC/NR2F6/EYS/TAF1/NPM1/OPN4/POLD3/SDF4	42
CC	GO:0005925	focal adhesion	70/1960	405/19717	3.002e-06	0.001315	0.001221	MMP14/LIMD1/FGFR3/CAV1/TES/PPFIBP1/PPP1CC/MRC2/TNS1/SLC9A1/ARPC2/ITGA6/FLNB/PIP5K1C/PARVG/DAB2/GNB2/ACTG1/CD9/PDGFRB/CAPN2/YWHAE/RRAS2/LPXN/ARHGAP31/JAK1/PTK2/ARHGEF7/ACTN1/DLC1/NFASC/ITGA3/SPRY4/CAV3/CORO2B/TGFB1I1/CBL/CSPG4/PPFIA1/ARHGAP22/MAPK3/MARCKS/ITGB2/ASAP3/SLC9A3R2/PDCD6IP/RPS10/LASP1/THY1/CAP1/IGF2R/FLRT1/FBLIM1/FLRT2/HSPG2/FZD2/DPP4/CSRP1/XIRP1/HMGA1/WASF1/AHNAK/ACTN4/CLTC/NPM1/GJA1/CDC42/ARF1/ITGB5/FZD1	70
CC	GO:0005924	cell-substrate adherens junction	70/1960	408/19717	3.918e-06	0.001315	0.001221	MMP14/LIMD1/FGFR3/CAV1/TES/PPFIBP1/PPP1CC/MRC2/TNS1/SLC9A1/ARPC2/ITGA6/FLNB/PIP5K1C/PARVG/DAB2/GNB2/ACTG1/CD9/PDGFRB/CAPN2/YWHAE/RRAS2/LPXN/ARHGAP31/JAK1/PTK2/ARHGEF7/ACTN1/DLC1/NFASC/ITGA3/SPRY4/CAV3/CORO2B/TGFB1I1/CBL/CSPG4/PPFIA1/ARHGAP22/MAPK3/MARCKS/ITGB2/ASAP3/SLC9A3R2/PDCD6IP/RPS10/LASP1/THY1/CAP1/IGF2R/FLRT1/FBLIM1/FLRT2/HSPG2/FZD2/DPP4/CSRP1/XIRP1/HMGA1/WASF1/AHNAK/ACTN4/CLTC/NPM1/GJA1/CDC42/ARF1/ITGB5/FZD1	70
CC	GO:0030055	cell-substrate junction	70/1960	412/19717	5.549e-06	0.001315	0.001221	MMP14/LIMD1/FGFR3/CAV1/TES/PPFIBP1/PPP1CC/MRC2/TNS1/SLC9A1/ARPC2/ITGA6/FLNB/PIP5K1C/PARVG/DAB2/GNB2/ACTG1/CD9/PDGFRB/CAPN2/YWHAE/RRAS2/LPXN/ARHGAP31/JAK1/PTK2/ARHGEF7/ACTN1/DLC1/NFASC/ITGA3/SPRY4/CAV3/CORO2B/TGFB1I1/CBL/CSPG4/PPFIA1/ARHGAP22/MAPK3/MARCKS/ITGB2/ASAP3/SLC9A3R2/PDCD6IP/RPS10/LASP1/THY1/CAP1/IGF2R/FLRT1/FBLIM1/FLRT2/HSPG2/FZD2/DPP4/CSRP1/XIRP1/HMGA1/WASF1/AHNAK/ACTN4/CLTC/NPM1/GJA1/CDC42/ARF1/ITGB5/FZD1	70
CC	GO:0062023	collagen-containing extracellular matrix	67/1960	406/19717	2.303e-05	0.004094	0.0038	TNXB/CSTB/FGL2/LTBP2/TIMP2/MXRA7/MFGE8/LUM/ADIPOQ/NID1/ADAMTS4/ITGA6/ECM1/COL4A2/CLEC3B/COL13A1/LOXL2/VIT/COL4A1/DCN/SERPINB12/COL9A1/A2M/ELANE/COL7A1/THBS4/COL1A1/PRG4/S100A4/CTSC/ZP3/LGALS3/MFAP4/TGFB1I1/PRELP/CSPG4/ADAMTS8/VWF/LAMA4/COL15A1/SPP2/COL5A2/APOC3/SERPINC1/MMRN1/SLPI/COL4A5/LAMA3/POSTN/SOD3/AMTN/ADAMTS2/FBLN1/S100A9/SOST/C17orf58/ANXA11/ADAMTS10/HSPG2/HTRA1/NPPA/LMAN1L/ADAM11/EYS/COL14A1/ITIH4/CTSH	67
CC	GO:0005938	cell cortex	49/1960	308/19717	0.0006436	0.08583	0.07968	RHOJ/SLC4A1/CAV1/RIC8B/FRY/MYO1D/FLNB/CAP2/FER/WIPF3/CAPN2/PHLDB1/RHOQ/SLC2A1/SPTBN5/PTK2/ARHGEF7/DLC1/KNCN/STIM1/ARHGAP32/MYO9B/HIP1/MARCKS/AKAP13/KCNC3/LASP1/TRAK1/RAPGEF3/CAP1/FMN2/ASPH/EXOC4/RIMS2/RHOBTB3/PCLO/WIPF2/CAPZA3/RASAL3/RIMS3/UNC13A/ACTN4/CTBP1/AQP7/WAS/CDC42/MLPH/MELK/CRIP2	49
CC	GO:0101003	ficolin-1-rich granule membrane	15/1960	61/19717	0.0007379	0.08583	0.07968	TCIRG1/SERPINB12/NFASC/SIRPA/LGALS3/CD93/DOK3/AP2A2/ITGB2/LAMP1/MGAM/CD55/PKP1/ATP6V0A1/FPR1	15
CC	GO:0045121	membrane raft	49/1960	315/19717	0.001064	0.08583	0.07968	CAV1/HMOX1/SLC9A1/MYO1D/LDHB/SELPLG/CAPN2/PGK1/RHOQ/RIPK1/LCK/PLLP/RAP2B/SLC9A3R1/SLC2A1/PTGIS/DLC1/STIM1/RET/ANGPT1/SMPD2/FYN/FAIM2/CAV3/LIPE/FURIN/EFHD2/CBL/PLVAP/MAPK3/ITGB2/PECAM1/TRPM8/TGFBR1/LAT/CD55/THY1/MYOF/PRKACA/P2RX3/PPT1/DPP4/KCNA3/AHNAK/GJA1/TNFRSF1A/RTN4R/CD177/TLR1	49
CC	GO:0098857	membrane microdomain	49/1960	316/19717	0.001141	0.08583	0.07968	CAV1/HMOX1/SLC9A1/MYO1D/LDHB/SELPLG/CAPN2/PGK1/RHOQ/RIPK1/LCK/PLLP/RAP2B/SLC9A3R1/SLC2A1/PTGIS/DLC1/STIM1/RET/ANGPT1/SMPD2/FYN/FAIM2/CAV3/LIPE/FURIN/EFHD2/CBL/PLVAP/MAPK3/ITGB2/PECAM1/TRPM8/TGFBR1/LAT/CD55/THY1/MYOF/PRKACA/P2RX3/PPT1/DPP4/KCNA3/AHNAK/GJA1/TNFRSF1A/RTN4R/CD177/TLR1	49
CC	GO:0044420	extracellular matrix component	13/1960	51/19717	0.001141	0.08583	0.07968	LUM/COL4A2/COL4A1/COL7A1/COL1A1/MFAP4/COL15A1/COL5A2/COL4A5/LAMA3/FBLN1/ADAMTS10/COL14A1	13
CC	GO:0005769	early endosome	53/1960	350/19717	0.001274	0.08583	0.07968	PLA2G4B/SNX27/RAB31/SH3GL1/STAM2/CAV1/TRAK2/HAVCR2/SORT1/MYO1D/SNX31/VPS18/PLEKHF2/FGD5/LIPG/MYO1B/RAB32/C8orf44-SGK3/EHD4/FCGR1B/RAB11FIP5/RET/EHD1/REP15/CNTNAP2/EPHA3/LNPEP/MAPK3/COMMD1/APOC3/TOM1/KCNH1/TRAK1/RAPGEF1/SIAH1/APH1A/WLS/IGF2R/CLVS1/STAM/SORCS2/TMEM127/GPNMB/ANKRD13B/CACNG7/GRIA1/GJA1/WASF2/CLCN5/PICK1/FGD2/RCC2/CFTR	53
CC	GO:0005911	cell-cell junction	66/1960	459/19717	0.001404	0.08583	0.07968	PDZD3/LIMD1/RPGRIP1L/ARVCF/P2RX7/SCN1B/LDB3/PCDH12/C1QTNF5/SLC9A1/CLDN16/SPECC1L/ITGA6/ATP2A2/LRRC7/CLDN15/MYH1/KAZN/COL13A1/TRIM29/CDC42BPB/CDSN/AKT1/RAP2B/SLC2A1/ACTN1/NFASC/BAIAP2/TMOD3/ANK3/PPP1CA/CNTNAP2/CAV3/PIK3R1/DNMBP/BAIAP2L2/GJB3/PECAM1/PANX3/PDCD6IP/TBCD/ECT2/TGFBR1/PLCG1/LAT/ILDR1/ITK/AMTN/CD2AP/ANKRD23/FLRT1/FLRT2/PDLIM5/NDRG1/DPP4/MXRA8/AMOT/AHNAK/ACTN4/PKP1/AQP7/WAS/GJA1/WASF2/CDC42BPA/FAT2	66
CC	GO:0098589	membrane region	50/1960	328/19717	0.001488	0.08583	0.07968	CAV1/HMOX1/SLC9A1/MYO1D/LDHB/SELPLG/CAPN2/PGK1/RHOQ/RIPK1/LCK/PLLP/RAP2B/SLC9A3R1/SLC2A1/PTGIS/DLC1/FAM170B/STIM1/RET/ANGPT1/SMPD2/FYN/FAIM2/CAV3/LIPE/FURIN/EFHD2/CBL/PLVAP/MAPK3/ITGB2/PECAM1/TRPM8/TGFBR1/LAT/CD55/THY1/MYOF/PRKACA/P2RX3/PPT1/DPP4/KCNA3/AHNAK/GJA1/TNFRSF1A/RTN4R/CD177/TLR1	50
CC	GO:0098644	complex of collagen trimers	7/1960	19/19717	0.001628	0.08583	0.07968	LUM/COL4A2/COL4A1/COL7A1/COL1A1/COL5A2/COL4A5	7
CC	GO:0043292	contractile fiber	38/1960	234/19717	0.00169	0.08583	0.07968	TMOD4/SLC4A1/TNNC1/BIN1/MYL3/LDB3/SYNPO2L/FLNB/SCN3B/MYH1/LRRC39/ACTG1/CMYA5/MYH13/SLC2A1/TIMP4/ACTN1/TMOD3/ANK3/MYL5/CAV3/ARHGEF25/FBXO32/PECAM1/FHOD3/ANKRD23/TNNC2/SMN2/PDLIM5/CSRP1/RYR3/MYH15/AHNAK/ACTN4/GJA1/LMOD3/ARF1/SYNC	38
CC	GO:0030139	endocytic vesicle	46/1960	303/19717	0.002435	0.1089	0.101	CAMK2G/WNT3/RAB31/RAB11FIP4/CAV1/HBEGF/FLNB/ACTG1/CD9/CAMK2A/TCIRG1/CDC42EP2/RAB32/FCGR1B/ELANE/LMBRD1/HBA2/AMBRA1/HIP1/AP2A2/RAB12/RAPGEF6/ARRB2/LAMP1/NCF2/RAPGEF1/ATG5/CD2AP/WLS/IGF2R/ANXA11/FZD2/DPP4/CUBN/AMOT/KIAA1107/SFTPD/CD74/CLTC/GRIA1/WAS/PICK1/ITGB5/COLEC12/ATP6V0A1/TLR1	46
CC	GO:0030140	trans-Golgi network transport vesicle	9/1960	31/19717	0.00247	0.1089	0.101	SORT1/TGOLN2/AP1G1/RASSF9/FURIN/AP1S1/NCALD/IGF2R/CLTC	9
CC	GO:0010008	endosome membrane	67/1960	479/19717	0.002603	0.1089	0.101	PLA2G4B/SNX27/RAB31/RAB11FIP4/SH3GL1/STAM2/CAV1/SORT1/ARHGAP1/PIP5K1C/HLA-DOB/VPS18/SLC48A1/PLEKHF2/SPPL2B/TSPAN15/ECE1/TCIRG1/MYO1B/RIPK1/RAP2B/EHD4/STEAP3/FCGR1B/RAB11FIP5/TLR8/RET/EHD1/ARHGAP32/REP15/FURIN/AP3D1/MREG/AP2A2/IFITM3/RAB12/COMMD1/RFFL/LAMP1/NDFIP1/KCNH1/TPCN1/VPS53/TAB3/APH1A/WLS/UBAP1/CLVS1/STAM/SORCS2/TOM1L1/GPNMB/NDRG1/CUBN/PLEKHM1/SLC9A9/UBAP1L/CLTC/CD300LG/GRIA1/SLC9B2/SCAMP5/CLCN5/FGD2/ATP6V0A1/RCC2/CFTR	67
CC	GO:0030990	intraciliary transport particle	8/1960	27/19717	0.003705	0.1463	0.1359	IFT80/IFT74/IFT122/WDR19/IFT81/CLUAP1/TTC21B/IFT43	8
CC	GO:0032391	photoreceptor connecting cilium	10/1960	39/19717	0.003952	0.1479	0.1373	RPGRIP1L/CETN2/TBCC/SPTBN5/IFT122/CETN1/USH1G/WDR19/PCDHB15/FAM161A	10
CC	GO:0031143	pseudopodium	6/1960	17/19717	0.004511	0.151	0.1402	LDB3/CAPN2/ACTN1/MAPK3/ARRB1/ACTN4	6
CC	GO:0030016	myofibril	35/1960	224/19717	0.004751	0.151	0.1402	TMOD4/SLC4A1/TNNC1/BIN1/MYL3/LDB3/SYNPO2L/FLNB/SCN3B/MYH1/LRRC39/ACTG1/CMYA5/MYH13/SLC2A1/TIMP4/ACTN1/TMOD3/ANK3/CAV3/ARHGEF25/FBXO32/FHOD3/ANKRD23/TNNC2/SMN2/PDLIM5/CSRP1/RYR3/MYH15/AHNAK/ACTN4/LMOD3/ARF1/SYNC	35
CC	GO:0035869	ciliary transition zone	14/1960	66/19717	0.004787	0.151	0.1402	RPGRIP1L/C5orf30/CETN2/TBCC/NEK4/SPTBN5/IFT122/CETN1/UNC119B/USH1G/WDR19/PCDHB15/FAM161A/CDKL1	14
CC	GO:0030863	cortical cytoskeleton	21/1960	116/19717	0.004885	0.151	0.1402	SLC4A1/CAP2/WIPF3/CAPN2/SLC2A1/SPTBN5/DLC1/KNCN/HIP1/AKAP13/LASP1/RAPGEF3/CAP1/RIMS2/PCLO/WIPF2/CAPZA3/RIMS3/ACTN4/WAS/MLPH	21
CC	GO:0005884	actin filament	20/1960	111/19717	0.006253	0.179	0.1662	SMTNL2/LDB3/SPECC1L/WIPF3/VPS18/ACTG1/MYO1B/RHOQ/SH2B2/SPTBN5/ACTN1/FYN/MYO9B/AKAP13/GAS2/CD2AP/PDLIM5/AMOT/WIPF2/WAS	20
CC	GO:0030136	clathrin-coated vesicle	30/1960	188/19717	0.006295	0.179	0.1662	HBEGF/SORT1/UNC13D/DAB2/VPS18/CD9/TGOLN2/ECE1/TNK2/FCGR1B/AP1G1/LMBRD1/RASSF9/HIP1/FURIN/AP2A2/VWF/FOLR1/AP1S1/NCALD/IGF2R/CLVS1/FZD2/EGF/KIAA1107/SFTPD/CD74/CLTC/ASTN1/CFTR	30
CC	GO:0044449	contractile fiber part	34/1960	221/19717	0.006775	0.1853	0.172	TMOD4/SLC4A1/TNNC1/BIN1/MYL3/LDB3/SYNPO2L/FLNB/SCN3B/MYH1/LRRC39/CMYA5/MYH13/SLC2A1/TIMP4/ACTN1/TMOD3/ANK3/MYL5/CAV3/ARHGEF25/FBXO32/PECAM1/FHOD3/TNNC2/SMN2/PDLIM5/CSRP1/RYR3/AHNAK/ACTN4/LMOD3/ARF1/SYNC	34
CC	GO:0031594	neuromuscular junction	15/1960	76/19717	0.007208	0.1898	0.1762	P2RX7/PDZRN3/STXBP5L/RAPSN/FCHSD2/SYNJ2BP/ANK3/CAV3/SYNGR1/COL4A5/POSTN/PRKACA/TRIP4/UNC13A/SYNC	15
CC	GO:0031089	platelet dense granule lumen	5/1960	14/19717	0.008976	0.2279	0.2116	ECM1/CLEC3B/CTSW/SPP2/ITIH4	5
CC	GO:0005788	endoplasmic reticulum lumen	44/1960	309/19717	0.00949	0.2327	0.216	NOTUM/WNT3/MFGE8/APOL1/COL4A2/COL13A1/COL4A1/TSPAN15/TGOLN2/CSF1/MZB1/APOA5/COL9A1/P4HA1/ADAMTSL1/COL7A1/COL1A1/STC2/CTSC/TMEM43/PDIA5/SPP1/COL15A1/SPP2/COL5A2/APLP2/SERPINC1/SIL1/SRL/IGFBP4/COL4A5/RDH5/AMTN/IL12B/SERPIND1/TRDN/MXRA8/PNPLA2/FLT3/FAM20C/COL14A1/EDEM3/FMO1/SCG2	44
CC	GO:0043194	axon initial segment	6/1960	20/19717	0.0109	0.2441	0.2266	BIN1/TRIM46/LRRC7/NFASC/ANK3/MAP2	6
CC	GO:0097060	synaptic membrane	58/1960	432/19717	0.01117	0.2441	0.2266	SIPA1L1/LRRC7/GRIN2C/COMT/COL13A1/BCR/CAMK2A/NPTN/GLRA2/RNF112/RAPSN/SLITRK1/ADAM23/ITGA3/KCNJ9/BAIAP2/NTNG1/DAGLA/ARHGAP32/SYNJ2BP/ANK3/FAIM2/GABRR3/SNAP25/HIP1/ARRB2/KCNC3/CLSTN1/SEMA4C/ADORA2A/CAMK2N1/KCNH1/LRRTM1/APH1A/GRM8/CNTN6/P2RX3/ARRB1/APBB1/PDLIM5/NTRK3/RIMS2/LRFN1/KIAA1107/KCNA3/SHISA9/GRIN3B/RIMS3/UNC13A/CACNG7/ROGDI/DCC/GRIA1/ARF1/PICK1/TMEM240/LRRTM4/GRIP2	58
CC	GO:0005581	collagen trimer	16/1960	87/19717	0.01118	0.2441	0.2266	LUM/ADIPOQ/C1QTNF5/COL4A2/COL13A1/COL4A1/DCN/COL9A1/COL7A1/COL1A1/COL15A1/COL5A2/COL4A5/SFTPD/COL14A1/COLEC12	16
CC	GO:0070820	tertiary granule	26/1960	164/19717	0.01133	0.2441	0.2266	CSTB/TIMP2/TCIRG1/RAP2B/SERPINB12/NFASC/SIRPA/CAMP/LGALS3/CD93/SNAP25/DOK3/AP2A2/ITGB2/LAMP1/TARM1/MGAM/CD55/CLEC5A/FTH1/PKP1/SVIP/CTSH/CD177/ATP6V0A1/FPR1	26
CC	GO:0012510	trans-Golgi network transport vesicle membrane	5/1960	15/19717	0.01238	0.2589	0.2403	AP1G1/RASSF9/AP1S1/NCALD/CLTC	5
CC	GO:0030864	cortical actin cytoskeleton	16/1960	90/19717	0.01529	0.2904	0.2696	CAP2/WIPF3/CAPN2/SLC2A1/SPTBN5/DLC1/KNCN/HIP1/AKAP13/LASP1/RAPGEF3/CAP1/WIPF2/CAPZA3/WAS/MLPH	16
CC	GO:0044304	main axon	13/1960	68/19717	0.01541	0.2904	0.2696	BIN1/SCN1B/TRIM46/MYO1D/LRRC7/NFASC/DAGLA/ANK3/CNTNAP2/MAP2/ADORA2A/THY1/APBB1	13
CC	GO:0030027	lamellipodium	29/1960	193/19717	0.01589	0.2904	0.2696	PIEZO1/ITGB1BP1/SLC9A1/ARPC2/FER/CDC42BPB/FGD5/RUFY3/ARHGAP31/PTK2/ARHGEF7/DGKZ/MYO1G/CSPG4/ROCK1/PLCG1/RAPGEF3/IQGAP2/APBB1/DPP4/AMOT/DYNLT1/PTPN13/WASF1/WASF2/CDC42BPA/PLXND1/CD177/FGD2	29
CC	GO:0030479	actin cortical patch	5/1960	16/19717	0.01656	0.2904	0.2696	WIPF3/HIP1/WIPF2/CAPZA3/WAS	5
CC	GO:0061645	endocytic patch	5/1960	16/19717	0.01656	0.2904	0.2696	WIPF3/HIP1/WIPF2/CAPZA3/WAS	5
CC	GO:0098831	presynaptic active zone cytoplasmic component	5/1960	16/19717	0.01656	0.2904	0.2696	RIMS2/PCLO/RIMS3/UNC13A/CTBP1	5
CC	GO:0005905	clathrin-coated pit	13/1960	69/19717	0.01731	0.2904	0.2696	SORT1/DAB2/RAMP2/FCHSD2/TNK2/HIP1/AP2A2/ARRB2/AP1S1/ARRB1/CUBN/KIAA1107/CLTC	13
CC	GO:0005798	Golgi-associated vesicle	27/1960	178/19717	0.01736	0.2904	0.2696	SORT1/PEF1/SEC16B/SPPL2B/TGOLN2/RHOQ/TMED7/AP1G1/MAP6/SEC31B/COL7A1/VMA21/CTSC/RASSF9/FURIN/FOLR1/MAP6D1/AP1S1/NCALD/IGF2R/LMAN1L/CD74/CLTC/GRIA1/GJA1/ARF1/CFTR	27
CC	GO:0005802	trans-Golgi network	34/1960	236/19717	0.01756	0.2904	0.2696	RAB31/CHST2/COG3/NMNAT2/CHST3/TGOLN2/CHID1/MYO1B/COG7/RAB32/CORO7/PREPL/AP1G1/OSBP/RGP1/SNAP25/FURIN/RAB12/CHST1/ATXN2/AP1S1/VPS53/POSTN/PRKD1/WLS/IGF2R/CLVS1/RHOBTB3/CD74/CLTC/SCAMP5/CHST4/ARF1/PICK1	34
CC	GO:0002116	semaphorin receptor complex	4/1960	11/19717	0.01813	0.293	0.272	PLXNC1/PLXNB2/PLXNA2/PLXND1	4
CC	GO:0030017	sarcomere	30/1960	204/19717	0.01897	0.2997	0.2782	TMOD4/SLC4A1/TNNC1/BIN1/MYL3/LDB3/SYNPO2L/FLNB/SCN3B/MYH1/LRRC39/CMYA5/SLC2A1/TIMP4/ACTN1/TMOD3/ANK3/CAV3/ARHGEF25/FBXO32/FHOD3/TNNC2/SMN2/PDLIM5/CSRP1/RYR3/ACTN4/LMOD3/ARF1/SYNC	30
CC	GO:0030135	coated vesicle	40/1960	289/19717	0.01988	0.3072	0.2852	HBEGF/SORT1/UNC13D/PEF1/DAB2/VPS18/SEC16B/CD9/TGOLN2/ECE1/TMED7/TNK2/FCGR1B/AP1G1/SEC31B/LMBRD1/COL7A1/VMA21/CTSC/RASSF9/HIP1/FURIN/AP2A2/VWF/FOLR1/AP1S1/NCALD/IGF2R/CLVS1/FZD2/EGF/KIAA1107/LMAN1L/SFTPD/CD74/CLTC/GRIA1/ARF1/ASTN1/CFTR	40
CC	GO:0030125	clathrin vesicle coat	7/1960	29/19717	0.0209	0.3077	0.2856	AP1G1/HIP1/AP2A2/AP1S1/NCALD/KIAA1107/CLTC	7
CC	GO:0098793	presynapse	63/1960	491/19717	0.02098	0.3077	0.2856	SYT8/BIN1/SH3GL1/P2RX7/PTPRN/PPP1CC/RGS10/PIP5K1C/VPS18/ACTG1/NPTN/SLC29A1/RNF112/TNIK/MCTP1/ADAM23/KCNJ9/CYP46A1/BAIAP2/SCGN/NTNG1/PPP1CA/DMXL2/SNAP25/SYNGR1/RAB33B/HIP1/DNMBP/AP3D1/PPFIA1/TH/KCNC3/SEMA4C/LAMP1/ADORA2A/AP1S1/KCNH1/NPFF/APH1A/GRM8/CNTN6/P2RX3/APBB1/SYT12/PPT1/RIMS2/PCLO/CACNB2/HRH3/SYT4/KIAA1107/KCNA3/PRKCB/RIMS3/UNC13A/ROGDI/CTBP1/GRIA1/SLC9B2/SCAMP5/RTN4R/PICK1/NTF3	63
CC	GO:0044853	plasma membrane raft	18/1960	109/19717	0.02156	0.3077	0.2856	CAV1/HMOX1/MYO1D/SELPLG/SLC2A1/PTGIS/DLC1/STIM1/SMPD2/CAV3/LIPE/CBL/PLVAP/MAPK3/ITGB2/MYOF/PRKACA/CD177	18
CC	GO:0044291	cell-cell contact zone	13/1960	71/19717	0.02164	0.3077	0.2856	SCN1B/SLC9A1/MYH1/RAP2B/SLC2A1/ACTN1/ANK3/CAV3/BAIAP2L2/PECAM1/ANKRD23/AHNAK/GJA1	13
CC	GO:0043202	lysosomal lumen	16/1960	95/19717	0.02463	0.3366	0.3125	LUM/PDGFRB/DCN/CHID1/NPC2/MAN2B1/PRELP/CSPG4/SGSH/EPDR1/SERPINB13/LGMN/PPT1/HSPG2/CUBN/CD74	16
CC	GO:0030666	endocytic vesicle membrane	25/1960	167/19717	0.02482	0.3366	0.3125	CAMK2G/WNT3/RAB31/CAV1/HBEGF/CD9/CAMK2A/TCIRG1/RAB32/FCGR1B/HIP1/AP2A2/LAMP1/RAPGEF1/ATG5/WLS/FZD2/KIAA1107/CD74/CLTC/GRIA1/PICK1/COLEC12/ATP6V0A1/TLR1	25
CC	GO:0044615	nuclear pore nuclear basket	4/1960	12/19717	0.02509	0.3366	0.3125	CETN2/NUP153/MAD1L1/NUP35	4
CC	GO:0044448	cell cortex part	27/1960	184/19717	0.02564	0.337	0.3128	SLC4A1/CAP2/WIPF3/CAPN2/PHLDB1/SLC2A1/SPTBN5/DLC1/KNCN/STIM1/HIP1/AKAP13/LASP1/RAPGEF3/CAP1/ASPH/EXOC4/RIMS2/PCLO/WIPF2/CAPZA3/RIMS3/UNC13A/ACTN4/CTBP1/WAS/MLPH	27
CC	GO:0030669	clathrin-coated endocytic vesicle membrane	9/1960	44/19717	0.02692	0.337	0.3128	HBEGF/CD9/FCGR1B/HIP1/AP2A2/FZD2/KIAA1107/CD74/CLTC	9
CC	GO:0044441	ciliary part	59/1960	462/19717	0.02698	0.337	0.3128	RPGRIP1L/IFT80/C5orf30/GPR157/CETN2/LCA5L/SAG/GNA11/ENKUR/TBCC/CYS1/NEK4/AKT1/IFT74/SLC9A3R1/SPTBN5/NIN/AK2/KNCN/GPR37L1/EHD1/CDK10/CSNK1A1/AMBRA1/CEP170/IFT122/SPAG17/CETN1/CCDC63/ARHGAP35/UNC119B/TCTEX1D4/ARR3/USH1G/WDR19/TCTEX1D2/PHLPP2/TTLL6/ATG5/TBC1D30/PCDHB15/WRAP73/ARL6/PRKACA/IFT81/CLUAP1/MXRA8/CEP89/KIF3A/EYS/TTC21B/SUN5/SCNN1A/FAM161A/OPN4/SLC9B2/IQCE/CDKL1/IFT43	59
CC	GO:0101002	ficolin-1-rich granule	27/1960	185/19717	0.02728	0.337	0.3128	CSTB/PSMB7/PDAP1/FGL2/TIMP2/TCIRG1/SERPINB12/NFASC/CAB39/SIRPA/LGALS3/CD93/DOK3/AP2A2/ITGB2/LAMP1/CRISPLD2/MGAM/CD55/C1orf35/DYNLT1/FTH1/PKP1/CFD/CTSH/ATP6V0A1/FPR1	27
CC	GO:0099092	postsynaptic density, intracellular component	5/1960	18/19717	0.02749	0.337	0.3128	SH3GL1/BCR/TNIK/BAIAP2/FYN	5
CC	GO:0031252	cell leading edge	52/1960	403/19717	0.03051	0.3588	0.333	PIEZO1/ITGB1BP1/SLC9A1/MYO1D/ARPC2/EPS8L3/PIP5K1C/PSD2/FER/CDC42BPB/FGD5/RUFY3/SH2B2/ARHGAP31/SLC9A3R1/PTK2/ARHGEF7/ACTN1/DLC1/SPRY4/RINL/BAIAP2/DGKZ/MYO1G/CNTNAP2/CSPG4/ASAP3/ROCK1/KCNC3/ADORA2A/BMX/PLCG1/THY1/RAPGEF3/CD2AP/WLS/IQGAP2/APBB1/DPP4/AMOT/DYNLT1/PTPN13/SHISA9/WASF1/GRIA1/WASF2/PTK6/CDC42BPA/PLXND1/ARF1/CD177/FGD2	52
CC	GO:0014069	postsynaptic density	43/1960	324/19717	0.0307	0.3588	0.333	SH3GL1/SIPA1L1/NCK2/LRRC7/GRIN2C/CAP2/BCR/CAMK2A/NPTN/SYNGAP1/RNF112/TNIK/SLITRK1/BAIAP2/DGKZ/ARHGAP32/SYNJ2BP/PLCB4/FYN/ARRB2/CLSTN1/SEMA4C/MAP2/ADORA2A/CAMK2N1/KCNH1/CAMK1/DNAJB1/ARRB1/PDLIM5/SORCS2/TSC2/PCLO/LRFN1/SHISA9/CACNG7/DCC/GRIA1/ARF1/PICK1/PAK3/ARFGAP1/GRIP2	43
CC	GO:0097542	ciliary tip	9/1960	45/19717	0.03078	0.3588	0.333	IFT80/IFT74/IFT122/WDR19/IFT81/CLUAP1/KIF3A/TTC21B/IFT43	9
CC	GO:0030130	clathrin coat of trans-Golgi network vesicle	4/1960	13/19717	0.03346	0.3715	0.3449	AP1G1/AP1S1/NCALD/CLTC	4
CC	GO:0005775	vacuolar lumen	25/1960	172/19717	0.03411	0.3715	0.3449	LUM/UNC13D/PYCARD/PTGES2/PDGFRB/DAPK2/DCN/CHID1/ELANE/NPC2/CTSC/MAN2B1/PRELP/CSPG4/TOLLIP/SGSH/EPDR1/SERPINB13/CAP1/LGMN/PPT1/HSPG2/PADI2/CUBN/CD74	25
CC	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	15/1960	91/19717	0.03434	0.3715	0.3449	ERRFI1/ATP2A2/GNG4/FER/GNA11/PLEKHA4/LCK/GNG10/FYN/STAC2/SNAP25/HIP1/GNAS/PTK6/ESYT2	15
CC	GO:0031941	filamentous actin	7/1960	32/19717	0.03473	0.3715	0.3449	SMTNL2/LDB3/SPECC1L/ACTG1/SPTBN5/CD2AP/PDLIM5	7
CC	GO:0030665	clathrin-coated vesicle membrane	18/1960	115/19717	0.03495	0.3715	0.3449	HBEGF/DAB2/CD9/TGOLN2/FCGR1B/AP1G1/RASSF9/HIP1/AP2A2/AP1S1/NCALD/IGF2R/FZD2/EGF/KIAA1107/CD74/CLTC/CFTR	18
CC	GO:0030118	clathrin coat	9/1960	46/19717	0.03501	0.3715	0.3449	AP1G1/HIP1/BAIAP2L2/AP2A2/AP1S1/NCALD/IGF2R/KIAA1107/CLTC	9
CC	GO:0032279	asymmetric synapse	43/1960	328/19717	0.03658	0.3751	0.3482	SH3GL1/SIPA1L1/NCK2/LRRC7/GRIN2C/CAP2/BCR/CAMK2A/NPTN/SYNGAP1/RNF112/TNIK/SLITRK1/BAIAP2/DGKZ/ARHGAP32/SYNJ2BP/PLCB4/FYN/ARRB2/CLSTN1/SEMA4C/MAP2/ADORA2A/CAMK2N1/KCNH1/CAMK1/DNAJB1/ARRB1/PDLIM5/SORCS2/TSC2/PCLO/LRFN1/SHISA9/CACNG7/DCC/GRIA1/ARF1/PICK1/PAK3/ARFGAP1/GRIP2	43
CC	GO:0017053	transcriptional repressor complex	14/1960	84/19717	0.03683	0.3751	0.3482	INSM1/NCOR2/PRDM16/RCOR2/RCOR1/CSNK2A1/INSM2/GPS2/ELANE/HDAC3/ZBTB7A/ETV3/CTBP1/PHF12	14
CC	GO:0032588	trans-Golgi network membrane	15/1960	92/19717	0.0374	0.3751	0.3482	RAB31/COG3/MYO1B/COG7/AP1G1/RGP1/AP1S1/VPS53/IGF2R/CLVS1/RHOBTB3/CD74/CLTC/SCAMP5/PICK1	15
CC	GO:0098852	lytic vacuole membrane	46/1960	355/19717	0.03746	0.3751	0.3482	SORT1/ANPEP/ACPP/HLA-DOB/GNA11/DAB2/GNB2/VPS18/SLC48A1/SPPL2B/ECE1/TCIRG1/VASN/ATP6V1C1/CYBRD1/GNB4/AP1G1/RRAGA/LMBRD1/TLR8/SYNGR1/LNPEP/SLC39A11/AP3D1/MREG/AP2A2/IFITM3/RAB12/LAMP1/LPCAT1/TOM1/AP1S1/TPCN1/IGF2R/ARRB1/DPP4/CUBN/PLEKHM1/EGF/CD74/AHNAK/CLTC/CLCN5/ATP6V0A1/FPR1/CFTR	46
CC	GO:0031901	early endosome membrane	22/1960	149/19717	0.03847	0.3788	0.3516	PLA2G4B/SNX27/RAB31/SH3GL1/STAM2/CAV1/PLEKHF2/EHD4/FCGR1B/RAB11FIP5/EHD1/REP15/KCNH1/WLS/CLVS1/STAM/SORCS2/GPNMB/GRIA1/FGD2/RCC2/CFTR	22
CC	GO:0030658	transport vesicle membrane	29/1960	208/19717	0.03889	0.3788	0.3516	SYT8/PTPRN/PEF1/SEC16B/TMED7/MCTP1/AP1G1/SCGN/RAB11FIP5/MAP6/SEC31B/VMA21/DMXL2/RASSF9/SYNGR1/FOLR1/SEMA4C/LAMP1/AP1S1/NCALD/SYT12/SYT4/CD74/UNC13A/CLTC/GRIA1/SLC9B2/SCAMP5/CHGA	29
CC	GO:0030133	transport vesicle	50/1960	392/19717	0.03977	0.3821	0.3547	SYT8/FGFR3/BIN1/PTPRN/SORT1/C1QTNF5/UNC13D/PEF1/SEC16B/PLEKHF2/TGOLN2/RNF112/TMED7/MCTP1/AP1G1/SCGN/RAB11FIP5/MAP6/SEC31B/SYT15/VMA21/DMXL2/SNAP25/RASSF9/SYNGR1/FURIN/FOLR1/TH/SEMA4C/LAMP1/AP1S1/CRISPLD2/CD55/APH1A/NCALD/IGF2R/SYT12/PPT1/SYT4/KIAA1107/CD74/UNC13A/ROGDI/CLTC/GRIA1/SLC9B2/SCAMP5/PICK1/CHGA/NTF3	50
CC	GO:0099572	postsynaptic specialization	45/1960	348/19717	0.04039	0.3829	0.3555	SH3GL1/SIPA1L1/NCK2/LRRC7/GRIN2C/CAP2/BCR/CAMK2A/NPTN/SYNGAP1/RNF112/TNIK/RAPSN/SLITRK1/BAIAP2/DGKZ/ARHGAP32/SYNJ2BP/PLCB4/FYN/ARRB2/CLSTN1/SEMA4C/MAP2/ADORA2A/CAMK2N1/KCNH1/LRRTM1/CAMK1/DNAJB1/ARRB1/PDLIM5/SORCS2/TSC2/PCLO/LRFN1/SHISA9/CACNG7/DCC/GRIA1/ARF1/PICK1/PAK3/ARFGAP1/GRIP2	45
CC	GO:0098978	glutamatergic synapse	45/1960	349/19717	0.04207	0.3844	0.3568	SH3GL1/PLCB1/PPP1CC/ARPC2/GRIN2C/PSD2/VPS18/BCR/NPTN/YWHAE/SYNGAP1/TNIK/SLITRK1/ADAM23/ACTN1/BAIAP2/NTNG1/DGKZ/PLCB4/FYN/PPP1CA/SNAP25/HIP1/AP3D1/ARHGAP22/CLSTN1/ADORA2A/DGKE/PLCG1/LRRTM1/CAMK1/DNAJB1/NTRK3/NDRG1/SYT4/KCNA3/SHISA9/UNC13A/CACNG7/CTBP1/GRIA1/ARF1/RTN4R/PAK3/GRIP2	45
CC	GO:0030673	axolemma	4/1960	14/19717	0.04325	0.3844	0.3568	MYO1D/CNTNAP2/ADORA2A/THY1	4
CC	GO:0033162	melanosome membrane	4/1960	14/19717	0.04325	0.3844	0.3568	RAB32/MREG/TH/GPNMB	4
CC	GO:0045009	chitosome	4/1960	14/19717	0.04325	0.3844	0.3568	RAB32/MREG/TH/GPNMB	4
CC	GO:0090741	pigment granule membrane	4/1960	14/19717	0.04325	0.3844	0.3568	RAB32/MREG/TH/GPNMB	4
CC	GO:0098984	neuron to neuron synapse	45/1960	350/19717	0.04379	0.3844	0.3568	SH3GL1/SIPA1L1/NCK2/LRRC7/GRIN2C/CAP2/BCR/CAMK2A/NPTN/SYNGAP1/RNF112/TNIK/SLITRK1/BAIAP2/DGKZ/ARHGAP32/SYNJ2BP/PLCB4/FYN/ARRB2/CLSTN1/SEMA4C/MAP2/ADORA2A/CAMK2N1/KCNH1/CAMK1/DNAJB1/P2RX3/ARRB1/SYT12/PDLIM5/SORCS2/TSC2/PCLO/LRFN1/SHISA9/CACNG7/DCC/GRIA1/ARF1/PICK1/PAK3/ARFGAP1/GRIP2	45
CC	GO:0045334	clathrin-coated endocytic vesicle	11/1960	63/19717	0.04484	0.3876	0.3598	HBEGF/CD9/FCGR1B/LMBRD1/HIP1/AP2A2/FZD2/KIAA1107/SFTPD/CD74/CLTC	11
CC	GO:0030667	secretory granule membrane	39/1960	298/19717	0.04567	0.3876	0.3598	ALDH3B1/RAB31/CAV1/ANPEP/ACPP/CD9/TCIRG1/RAP2B/SERPINB12/FAM170B/NFASC/DGAT1/SIRPA/LGALS3/CD93/SNAP25/SYNGR1/DOK3/CD109/AP2A2/ORMDL3/ITGB2/PECAM1/LAMP1/LPCAT1/APLP2/TOM1/TARM1/MGAM/CD55/IQGAP2/IGF2R/CLEC5A/SYT4/PKP1/SVIP/CD177/ATP6V0A1/FPR1	39
CC	GO:0097431	mitotic spindle pole	6/1960	27/19717	0.0458	0.3876	0.3598	EML1/FAM83D/NIN/MAD1L1/TNKS/FAM161A	6
CC	GO:0042827	platelet dense granule	5/1960	21/19717	0.05095	0.4124	0.3828	ECM1/CLEC3B/CTSW/SPP2/ITIH4	5
CC	GO:0099091	postsynaptic specialization, intracellular component	5/1960	21/19717	0.05095	0.4124	0.3828	SH3GL1/BCR/TNIK/BAIAP2/FYN	5
CC	GO:0005765	lysosomal membrane	45/1960	354/19717	0.05124	0.4124	0.3828	SORT1/ANPEP/ACPP/HLA-DOB/GNA11/DAB2/GNB2/VPS18/SLC48A1/SPPL2B/ECE1/TCIRG1/VASN/ATP6V1C1/CYBRD1/GNB4/AP1G1/RRAGA/LMBRD1/TLR8/SYNGR1/LNPEP/AP3D1/MREG/AP2A2/IFITM3/RAB12/LAMP1/LPCAT1/TOM1/AP1S1/TPCN1/IGF2R/ARRB1/DPP4/CUBN/PLEKHM1/EGF/CD74/AHNAK/CLTC/CLCN5/ATP6V0A1/FPR1/CFTR	45
CC	GO:0030117	membrane coat	15/1960	96/19717	0.05162	0.4124	0.3828	PEF1/VPS18/TMED7/AP1G1/SEC31B/HIP1/BAIAP2L2/AP3D1/AP2A2/AP1S1/NCALD/ARL6/IGF2R/KIAA1107/CLTC	15
CC	GO:0048475	coated membrane	15/1960	96/19717	0.05162	0.4124	0.3828	PEF1/VPS18/TMED7/AP1G1/SEC31B/HIP1/BAIAP2L2/AP3D1/AP2A2/AP1S1/NCALD/ARL6/IGF2R/KIAA1107/CLTC	15
CC	GO:0005639	integral component of nuclear inner membrane	4/1960	15/19717	0.05448	0.4165	0.3866	P2RX7/TMEM43/P2RX3/P2RX5	4
CC	GO:0031229	intrinsic component of nuclear inner membrane	4/1960	15/19717	0.05448	0.4165	0.3866	P2RX7/TMEM43/P2RX3/P2RX5	4
CC	GO:0031462	Cul2-RING ubiquitin ligase complex	4/1960	15/19717	0.05448	0.4165	0.3866	ZSWIM5/ZSWIM6/COMMD1/CUL2	4
CC	GO:0033268	node of Ranvier	4/1960	15/19717	0.05448	0.4165	0.3866	BIN1/SCN1B/NFASC/ANK3	4
CC	GO:0005667	transcription factor complex	46/1960	365/19717	0.05538	0.4167	0.3868	LIMD1/TLE6/SKOR1/RXRA/TAF1B/SSBP3/RCOR2/FOXF2/CREB1/TRERF1/TAF7L/GTF3C1/PBX2/RCOR1/PPARG/FOXE3/PMF1/NFATC3/TCF7L1/NR1I3/JUNB/TAL1/RBPJL/TAF1A/TAF5L/DMBX1/MYF6/TCF7L2/NEUROD1/NKX2-1/GTF2H2C/SUB1/FOS/NR4A1/VDR/TAF4/HMGA1/SMAD2/TAF1/CTBP1/GTF2E1/MMS19/ING2/MYF5/ZNF541/NR5A1	46
CC	GO:0014704	intercalated disc	9/1960	50/19717	0.05587	0.4167	0.3868	SCN1B/SLC9A1/MYH1/SLC2A1/ACTN1/ANK3/CAV3/ANKRD23/GJA1	9
CC	GO:0000118	histone deacetylase complex	10/1960	58/19717	0.05827	0.4167	0.3868	NCOR2/HDAC5/TRERF1/CSNK2A1/HDAC3/TAL1/ZBTB7A/ING2/PHF12/ZNF541	10
CC	GO:0005637	nuclear inner membrane	10/1960	58/19717	0.05827	0.4167	0.3868	P2RX7/MATR3/TMEM120B/TMEM43/DPY19L2P1/KCNH1/P2RX3/P2RX5/ERN1/SUN5	10
CC	GO:0030120	vesicle coat	10/1960	58/19717	0.05827	0.4167	0.3868	PEF1/TMED7/AP1G1/SEC31B/HIP1/AP2A2/AP1S1/NCALD/KIAA1107/CLTC	10
CC	GO:0030660	Golgi-associated vesicle membrane	17/1960	114/19717	0.05834	0.4167	0.3868	PEF1/SEC16B/SPPL2B/RHOQ/TMED7/AP1G1/SEC31B/VMA21/RASSF9/FOLR1/AP1S1/NCALD/CD74/CLTC/GRIA1/GJA1/CFTR	17
CC	GO:0030662	coated vesicle membrane	25/1960	182/19717	0.06019	0.4167	0.3868	HBEGF/PEF1/DAB2/SEC16B/CD9/TGOLN2/TMED7/FCGR1B/AP1G1/SEC31B/VMA21/RASSF9/HIP1/AP2A2/FOLR1/AP1S1/NCALD/IGF2R/FZD2/EGF/KIAA1107/CD74/CLTC/GRIA1/CFTR	25
CC	GO:0042629	mast cell granule	5/1960	22/19717	0.06073	0.4167	0.3868	PIK3CG/CBL/LAT/NPPA/CHGA	5
CC	GO:0097038	perinuclear endoplasmic reticulum	5/1960	22/19717	0.06073	0.4167	0.3868	CAPN2/CREB3L2/OSBP/FYN/PIK3R1	5
CC	GO:0001772	immunological synapse	7/1960	36/19717	0.06104	0.4167	0.3868	SNX27/HAVCR2/NPTN/LCK/LGALS3/PDCD6IP/LAT	7
CC	GO:0045211	postsynaptic membrane	41/1960	323/19717	0.06147	0.4167	0.3868	SIPA1L1/LRRC7/GRIN2C/COMT/COL13A1/BCR/CAMK2A/NPTN/GLRA2/RNF112/RAPSN/SLITRK1/DAGLA/ARHGAP32/SYNJ2BP/ANK3/FAIM2/GABRR3/HIP1/ARRB2/CLSTN1/SEMA4C/ADORA2A/CAMK2N1/KCNH1/LRRTM1/ARRB1/APBB1/PDLIM5/NTRK3/LRFN1/KCNA3/SHISA9/GRIN3B/CACNG7/DCC/GRIA1/ARF1/PICK1/LRRTM4/GRIP2	41
CC	GO:1990752	microtubule end	6/1960	29/19717	0.06209	0.4167	0.3868	SLAIN2/NIN/CLIP2/NCKAP5L/NAV3/CAMSAP1	6
CC	GO:0008328	ionotropic glutamate receptor complex	9/1960	51/19717	0.06212	0.4167	0.3868	LRRC7/GRIN2C/SYNJ2BP/OLFM3/SACM1L/SHISA9/GRIN3B/CACNG7/GRIA1	9
CC	GO:0044453	nuclear membrane part	4/1960	16/19717	0.06711	0.4418	0.4101	P2RX7/TMEM43/P2RX3/P2RX5	4
CC	GO:0071437	invadopodium	4/1960	16/19717	0.06711	0.4418	0.4101	RUFY3/ITGA3/AFAP1L1/DPP4	4
CC	GO:0030315	T-tubule	9/1960	52/19717	0.0688	0.4488	0.4166	BIN1/SCN1B/SLC9A1/ANK3/CAV3/CACNA2D1/CACNB2/CACNG7/AHNAK	9
CC	GO:0043197	dendritic spine	23/1960	169/19717	0.07502	0.4846	0.4498	SIPA1L1/PPP1CC/RGS10/COMT/CAMK2A/PTK2/BAIAP2/ARHGAP32/PPP1CA/ARRB2/KCNC3/CLSTN1/ITPKA/DNAJB1/PRKACA/P2RX3/ARRB1/APBB1/DOCK10/SHISA9/GRIA1/CDC42/ZMYND8	23
CC	GO:0098878	neurotransmitter receptor complex	9/1960	53/19717	0.07591	0.4846	0.4498	LRRC7/GRIN2C/SYNJ2BP/OLFM3/SACM1L/SHISA9/GRIN3B/CACNG7/GRIA1	9
CC	GO:0098562	cytoplasmic side of membrane	24/1960	178/19717	0.07634	0.4846	0.4498	SLC4A1/TRAF5/ERRFI1/ATP2A2/RASA3/GNG4/FER/GNA11/SPPL2B/PLEKHA4/LCK/GNG10/FYN/STAC2/RPS26/SNAP25/HIP1/TH/DNAJA1/RASAL3/GNAS/PTK6/ESYT2/PTPN4	24
CC	GO:0005774	vacuolar membrane	50/1960	412/19717	0.08034	0.4989	0.4631	SORT1/MAP1LC3B2/ANPEP/ACPP/HLA-DOB/GNA11/DAB2/GNB2/VPS18/SLC48A1/SPPL2B/ECE1/TCIRG1/VASN/ATP6V1C1/CYBRD1/GNB4/ATG9B/AP1G1/RRAGA/LMBRD1/TLR8/SYNGR1/LNPEP/MAN2B1/SLC39A11/AP3D1/MREG/AP2A2/IFITM3/RAB12/LAMP1/LPCAT1/TOM1/AP1S1/TPCN1/PRKD1/IGF2R/ARRB1/DPP4/CUBN/PLEKHM1/EGF/CD74/AHNAK/CLTC/CLCN5/ATP6V0A1/FPR1/CFTR	50
CC	GO:0031092	platelet alpha granule membrane	4/1960	17/19717	0.08113	0.4989	0.4631	CD9/CD109/PECAM1/APLP2	4
CC	GO:0005865	striated muscle thin filament	6/1960	31/19717	0.08139	0.4989	0.4631	TMOD4/TNNC1/TMOD3/FHOD3/TNNC2/LMOD3	6
CC	GO:0008305	integrin complex	6/1960	31/19717	0.08139	0.4989	0.4631	ITGA9/ITGA6/ITGA3/ITGB2/ITGA7/ITGB5	6
CC	GO:0044309	neuron spine	23/1960	171/19717	0.08305	0.5047	0.4685	SIPA1L1/PPP1CC/RGS10/COMT/CAMK2A/PTK2/BAIAP2/ARHGAP32/PPP1CA/ARRB2/KCNC3/CLSTN1/ITPKA/DNAJB1/PRKACA/P2RX3/ARRB1/APBB1/DOCK10/SHISA9/GRIA1/CDC42/ZMYND8	23
CC	GO:0090575	RNA polymerase II transcription factor complex	22/1960	163/19717	0.08596	0.5101	0.4735	RXRA/CREB1/TAF7L/PPARG/NR1I3/JUNB/TAF5L/MYF6/TCF7L2/NEUROD1/GTF2H2C/FOS/VDR/TAF4/HMGA1/SMAD2/TAF1/GTF2E1/MMS19/ING2/MYF5/NR5A1	22
CC	GO:0043025	neuronal cell body	59/1960	497/19717	0.08604	0.5101	0.4735	TIMP2/P2RX7/PTPRN/TRAK2/SKOR1/SORT1/SCN1B/FBXO31/MYO1D/RGS10/S100A5/OMP/TMEM100/FLNB/PSD2/PYCARD/PTBP2/CAPN2/RUFY3/PTPRF/ASS1/ARHGEF7/CPNE5/BAIAP2/KNCN/RET/CKB/PPP1CA/CNTNAP2/RBFOX3/DPYSL5/SMURF1/TH/KCNC3/LAMP1/MAP2/ADORA2A/CAMK2N1/KCNH1/NPFF/THY1/DNAJB1/P2RX3/FLRT1/CNNM4/SMN2/APBB1/PPT1/DYNLT1/SYT4/GRIN3B/CACNG7/ROGDI/GRIA1/SRR/CDC42/RTN4R/AGFG1/ASTN1	59
CC	GO:0005604	basement membrane	14/1960	95/19717	0.08667	0.5101	0.4735	NID1/ITGA6/COL4A2/LOXL2/COL4A1/COL7A1/THBS4/LAMA4/COL15A1/COL4A5/LAMA3/AMTN/FBLN1/HSPG2	14
CC	GO:0005583	fibrillar collagen trimer	3/1960	11/19717	0.08825	0.5101	0.4735	LUM/COL1A1/COL5A2	3
CC	GO:0061827	sperm head	3/1960	11/19717	0.08825	0.5101	0.4735	DNAJB1/WBP2NL/DEFB132	3
CC	GO:0098643	banded collagen fibril	3/1960	11/19717	0.08825	0.5101	0.4735	LUM/COL1A1/COL5A2	3
CC	GO:0042641	actomyosin	12/1960	79/19717	0.08992	0.5118	0.4751	LDB3/FLNB/CDC42BPB/SH2B2/PTK2/ACTN1/PDCD6IP/FBLIM1/PDLIM5/XIRP1/ACTN4/CDC42BPA	12
CC	GO:0016529	sarcoplasmic reticulum	11/1960	71/19717	0.09104	0.5118	0.4751	CAMK2G/ATP2A2/CMYA5/STIM1/THBS4/ANK3/CACNA2D1/SRL/ASPH/TRDN/RYR3	11
CC	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane	11/1960	71/19717	0.09104	0.5118	0.4751	PIEZO1/TMED7/COL7A1/VMA21/CTSC/FOLR1/CD55/WHAMMP3/LMAN1L/GRIA1/ERGIC1	11
CC	GO:0016323	basolateral plasma membrane	28/1960	217/19717	0.09142	0.5118	0.4751	CDH16/SLC4A1/ITGA9/BEST1/SLC9A1/MYO1D/ITGA6/LRRC7/DISP1/NOD1/SLC29A1/SLC2A1/ITGA3/SLC22A1/SYNJ2BP/ANK3/CD34/FOLR1/RHCG/ARRB2/SLCO1B3/ST14/NDRG4/CNNM4/ARRB1/CD300LG/SLC9B2/SLC4A11	28
CC	GO:0036379	myofilament	6/1960	32/19717	0.09216	0.5119	0.4752	TMOD4/TNNC1/TMOD3/FHOD3/TNNC2/LMOD3	6
CC	GO:0097733	photoreceptor cell cilium	16/1960	113/19717	0.09352	0.5154	0.4785	RPGRIP1L/CETN2/SAG/GNA11/TBCC/SPTBN5/IFT122/CETN1/ARR3/USH1G/WDR19/PHLPP2/PCDHB15/EYS/FAM161A/OPN4	16
CC	GO:0005859	muscle myosin complex	4/1960	18/19717	0.09645	0.5209	0.4836	MYL3/MYH1/MYH13/MYL5	4
CC	GO:0090723	growth cone part	4/1960	18/19717	0.09645	0.5209	0.4836	YWHAE/ITGA3/APBB1/EXOC4	4
CC	GO:0005901	caveola	12/1960	80/19717	0.09672	0.5209	0.4836	CAV1/HMOX1/SLC2A1/PTGIS/DLC1/SMPD2/CAV3/LIPE/CBL/PLVAP/MAPK3/MYOF	12
CC	GO:0044798	nuclear transcription factor complex	26/1960	201/19717	0.09856	0.5269	0.4891	RXRA/TAF1B/CREB1/TAF7L/GTF3C1/PPARG/NFATC3/NR1I3/JUNB/TAF1A/TAF5L/MYF6/TCF7L2/NEUROD1/GTF2H2C/FOS/VDR/TAF4/HMGA1/SMAD2/TAF1/GTF2E1/MMS19/ING2/MYF5/NR5A1	26
CC	GO:0042470	melanosome	15/1960	106/19717	0.1023	0.5286	0.4907	MMP14/SGSM2/YWHAE/SLC2A1/RAB32/SYNGR1/MREG/TH/PDCD6IP/LAMP1/CCT4/ANXA11/GPNMB/CLTC/ATP6V0A1	15
CC	GO:0048770	pigment granule	15/1960	106/19717	0.1023	0.5286	0.4907	MMP14/SGSM2/YWHAE/SLC2A1/RAB32/SYNGR1/MREG/TH/PDCD6IP/LAMP1/CCT4/ANXA11/GPNMB/CLTC/ATP6V0A1	15
CC	GO:0005811	lipid droplet	12/1960	81/19717	0.1038	0.5286	0.4907	CAV1/EHD1/PLIN1/HSD3B7/LIPE/TMEM135/LPCAT1/STARD13/PNPLA5/HSD17B11/PNPLA2/AQP7	12
CC	GO:0055038	recycling endosome membrane	12/1960	81/19717	0.1038	0.5286	0.4907	RAB11FIP4/RAP2B/EHD4/RAB11FIP5/EHD1/RAB12/RFFL/SORCS2/NDRG1/GRIA1/SCAMP5/CFTR	12
CC	GO:0030018	Z disc	18/1960	132/19717	0.104	0.5286	0.4907	SLC4A1/BIN1/LDB3/SYNPO2L/FLNB/SCN3B/SLC2A1/ACTN1/ANK3/CAV3/FBXO32/FHOD3/SMN2/PDLIM5/CSRP1/RYR3/ACTN4/SYNC	18
CC	GO:0045335	phagocytic vesicle	18/1960	132/19717	0.104	0.5286	0.4907	RAB31/FLNB/ACTG1/TCIRG1/CDC42EP2/RAB32/ELANE/AMBRA1/RAB12/LAMP1/NCF2/RAPGEF1/ATG5/ANXA11/WAS/ITGB5/ATP6V0A1/TLR1	18
CC	GO:0097731	9+0 non-motile cilium	16/1960	115/19717	0.1052	0.5286	0.4907	RPGRIP1L/CETN2/SAG/GNA11/TBCC/SPTBN5/IFT122/CETN1/ARR3/USH1G/WDR19/PHLPP2/PCDHB15/EYS/FAM161A/OPN4	16
CC	GO:0045177	apical part of cell	46/1960	384/19717	0.1055	0.5286	0.4907	PDZD3/AGER/FAT4/C1QTNF5/SLC9A1/AHCYL1/CD9/PDGFRB/NOD1/SLC29A1/TCIRG1/MYO1B/TNIK/ATP6V1C1/SLC9A3R1/SLC2A1/PTK2/NIN/KNCN/MIR181A2/SLC12A1/CSPG4/CD34/MREG/FOLR1/CNTFR/RHCG/RAPGEF6/SLC9A3R2/TMEM114/SLC4A5/CLCA4/MGAM/THY1/ZMYND10/LGMN/DPP4/CUBN/GNAS/SCNN1A/CD300LG/GJA1/SRR/SLC9B2/CLCN5/CFTR	46
CC	GO:0055037	recycling endosome	23/1960	176/19717	0.1056	0.5286	0.4907	RAB11FIP4/UNC13D/TNIK/RAP2B/FCHSD2/C8orf44-SGK3/EHD4/MCTP1/AP1G1/RAB11FIP5/EHD1/REP15/RASSF9/RAB12/COMMD1/RFFL/VPS53/SORCS2/NDRG1/SLC9A9/GRIA1/SCAMP5/CFTR	23
CC	GO:0017119	Golgi transport complex	3/1960	12/19717	0.1093	0.5336	0.4953	COG3/COG7/CDC42	3
CC	GO:1990454	L-type voltage-gated calcium channel complex	3/1960	12/19717	0.1093	0.5336	0.4953	CACNA2D1/CACNB2/CACNG7	3
CC	GO:1990909	Wnt signalosome	3/1960	12/19717	0.1093	0.5336	0.4953	WNT3/LRP5/FZD1	3
CC	GO:0034364	high-density lipoprotein particle	5/1960	26/19717	0.1096	0.5336	0.4953	APOL1/APOA5/LCAT/APOC1/APOC3	5
MF	GO:0030695	GTPase regulator activity	63/1807	304/17697	3.291e-08	3.57e-05	3.419e-05	ARHGAP15/FAM13A/ITGB1BP1/ALS2CL/PLCB1/SIPA1L1/AGAP11/ARHGAP1/ERRFI1/RIC8B/RGS10/RASA3/SGSM2/ACAP3/RASGRP3/BCR/ARHGEF10L/SYNGAP1/STXBP5L/AGAP1/CDC42EP2/SRGAP3/ARHGAP31/ARHGAP5/RANBP3/SRGAP1/TNK2/DLC1/ARHGEF12/GPS2/RUNDC3A/RINL/RGPD3/ARHGAP32/ARHGAP20/SIRPA/ASAP2/DOCK4/MYO9B/CHML/ARHGAP22/ARHGAP36/ASAP3/TBCD/ARHGAP35/ECT2/RASAL2/STARD13/TBC1D22A/THY1/TBC1D30/RAP1GAP/IQGAP2/ARRB1/DOCK5/TSC2/RGS11/TBC1D2/RASAL3/WAS/ARHGAP27/AGFG1/ARFGAP1	63
MF	GO:0060589	nucleoside-triphosphatase regulator activity	68/1807	344/17697	6.656e-08	3.611e-05	3.457e-05	BAG2/ARHGAP15/FAM13A/ITGB1BP1/ALS2CL/PLCB1/SIPA1L1/AGAP11/ARHGAP1/ERRFI1/RIC8B/RGS10/RASA3/SGSM2/ACAP3/RASGRP3/BCR/ARHGEF10L/SYNGAP1/STXBP5L/AGAP1/CDC42EP2/SRGAP3/ARHGAP31/ARHGAP5/RANBP3/SRGAP1/TNK2/DLC1/ARHGEF12/GPS2/RUNDC3A/RINL/RGPD3/ARHGAP32/ARHGAP20/SIRPA/ASAP2/DOCK4/MYO9B/CHML/ARHGAP22/ARHGAP36/ASAP3/TBCD/ARHGAP35/ECT2/RASAL2/SIL1/STARD13/TBC1D22A/FNIP2/THY1/TBC1D30/RAP1GAP/DNAJB1/IQGAP2/ARRB1/DOCK5/TSC2/RGS11/TBC1D2/DNAJA1/RASAL3/WAS/ARHGAP27/AGFG1/ARFGAP1	68
MF	GO:0005096	GTPase activator activity	56/1807	273/17697	2.686e-07	9.714e-05	9.302e-05	ARHGAP15/FAM13A/ALS2CL/PLCB1/SIPA1L1/AGAP11/ARHGAP1/ERRFI1/RIC8B/RGS10/RASA3/SGSM2/ACAP3/RASGRP3/BCR/ARHGEF10L/SYNGAP1/STXBP5L/AGAP1/CDC42EP2/SRGAP3/ARHGAP31/ARHGAP5/RANBP3/SRGAP1/DLC1/ARHGEF12/RINL/RGPD3/ARHGAP32/ARHGAP20/ASAP2/DOCK4/MYO9B/CHML/ARHGAP22/ARHGAP36/ASAP3/TBCD/ARHGAP35/ECT2/RASAL2/STARD13/TBC1D22A/THY1/TBC1D30/RAP1GAP/ARRB1/DOCK5/TSC2/RGS11/TBC1D2/RASAL3/ARHGAP27/AGFG1/ARFGAP1	56
MF	GO:0031267	small GTPase binding	79/1807	443/17697	5.48e-07	0.0001486	0.0001423	PLEKHG4/ARHGEF16/RAB11FIP4/CAV1/ARHGAP1/TRAPPC3/ERRFI1/EPS8L3/SGSM2/UNC13D/RASGRP3/MADD/FMNL2/INF2/BCR/ECT2L/CDC42BPB/FMNL3/ARHGEF10L/STXBP5L/FGD5/CDC42EP2/SRGAP3/DENND3/ARHGEF3/RANBP3/SRGAP1/ARHGEF7/ARHGEF12/AP1G1/RAB11FIP5/C15orf62/RGPD3/RGP1/EHD1/DMXL2/DOCK4/TRIO/MYO9B/CHML/DNMBP/ARHGEF25/RAPGEF6/AKAP13/ROCK1/DAAM2/ECT2/ITPKA/SIKE1/NCF2/RAPGEF1/TBC1D22A/RAPGEF3/TBC1D30/RAP1GAP/PEX5L/DENND4B/VAV2/CDC42EP5/IQGAP2/PIH1D2/EXOC4/RIMS2/TSC2/RHOBTB3/TMEM127/WHAMMP3/NDRG1/IPO11/TBC1D2/EGF/KIF3A/RIMS3/WASF1/WAS/MLPH/PAK3/FGD2/RCC2	79
MF	GO:0017048	Rho GTPase binding	40/1807	177/17697	1.061e-06	0.0002106	0.0002017	PLEKHG4/ARHGEF16/CAV1/EPS8L3/FMNL2/INF2/BCR/ECT2L/CDC42BPB/FMNL3/ARHGEF10L/FGD5/CDC42EP2/SRGAP3/ARHGEF3/SRGAP1/ARHGEF7/ARHGEF12/C15orf62/DOCK4/TRIO/MYO9B/DNMBP/ARHGEF25/AKAP13/ROCK1/DAAM2/ECT2/ITPKA/SIKE1/NCF2/VAV2/CDC42EP5/IQGAP2/WHAMMP3/WASF1/WAS/PAK3/FGD2/RCC2	40
MF	GO:0017016	Ras GTPase binding	76/1807	429/17697	1.165e-06	0.0002106	0.0002017	PLEKHG4/ARHGEF16/RAB11FIP4/CAV1/ARHGAP1/TRAPPC3/EPS8L3/SGSM2/UNC13D/RASGRP3/MADD/FMNL2/INF2/BCR/ECT2L/CDC42BPB/FMNL3/ARHGEF10L/STXBP5L/FGD5/CDC42EP2/SRGAP3/DENND3/ARHGEF3/RANBP3/SRGAP1/ARHGEF7/ARHGEF12/AP1G1/RAB11FIP5/C15orf62/RGPD3/RGP1/EHD1/DMXL2/DOCK4/TRIO/MYO9B/CHML/DNMBP/ARHGEF25/RAPGEF6/AKAP13/ROCK1/DAAM2/ECT2/ITPKA/SIKE1/NCF2/RAPGEF1/TBC1D22A/RAPGEF3/TBC1D30/RAP1GAP/DENND4B/VAV2/CDC42EP5/IQGAP2/PIH1D2/EXOC4/RIMS2/RHOBTB3/TMEM127/WHAMMP3/NDRG1/IPO11/TBC1D2/EGF/KIF3A/RIMS3/WASF1/WAS/MLPH/PAK3/FGD2/RCC2	76
MF	GO:0060090	molecular adaptor activity	43/1807	237/17697	0.0001344	0.02083	0.01994	WWC2/CAV1/NMD3/ARHGAP1/NCK2/SLC9A1/TRIM22/TP53BP2/PEF1/KHDRBS1/SMARCD1/DAB2/VPS18/CNOT1/SH2B2/LINC00324/SLC9A3R1/CHCHD3/CUX1/BAIAP2/ANK3/CAV3/HIP1/PIK3R1/AP2A2/TOB1/SLC9A3R2/ARRB2/AKAP13/SPSB4/LAT/LASP1/EIF4G1/FLRT1/FLRT2/ARRB1/STAM/TRDN/GAS2L1/SOCS2/COL14A1/MLPH/MMS19	43
MF	GO:0019902	phosphatase binding	35/1807	185/17697	0.000239	0.03242	0.03104	SH3GL1/PPP1CC/SLC9A1/FER/PPARG/AKT1/LCK/CLEC12B/SLC9A3R1/JAK1/CHCHD3/PTK2/PPP6R3/PPP1CA/PVRIG/SIRPA/CTSC/LGALS3/PIK3R1/CDC5L/MAPK3/JAK3/SLC9A3R2/FBXL2/PPP1R18/TCTEX1D4/ELL/CSF1R/SH2D4A/PPP1R3G/TSC2/TPRN/KIF3A/SMAD2/PPP1R35	35
MF	GO:0004715	non-membrane spanning protein tyrosine kinase activity	13/1807	46/17697	0.0005056	0.05227	0.05005	TNK1/FER/LCK/JAK1/PTK2/TNK2/FYN/JAK3/CLK1/BMX/ITK/PTK6/MELK	13
MF	GO:0051427	hormone receptor binding	34/1807	185/17697	0.0005063	0.05227	0.05005	NCOR2/TOB2/RXRA/LRIF1/PPARG/CNOT1/JAK1/FYN/NCOA7/TGFB1I1/CCDC62/ZBTB7A/THRAP3/NR0B1/LEP/TCF7L2/MED30/ARRB1/NR4A1/PROX1/PADI2/VDR/TRIP4/NPPA/PRKCB/HMGA1/GNAS/GAS2L1/NKX3-1/ACTN4/FLT3/TAF1/SOCS2/MMS19	34
MF	GO:0043548	phosphatidylinositol 3-kinase binding	10/1807	30/17697	0.0005299	0.05227	0.05005	PDGFRB/LCK/TYRO3/PIK3IP1/FYN/PIK3R1/CBL/FBXL2/RASD2/PTPN13	10
MF	GO:0005543	phospholipid binding	65/1807	427/17697	0.0006746	0.06099	0.0584	PLA2G4B/ZFYVE19/SESTD1/SNX27/SYT8/GRAMD1B/SDCBP2/BIN1/MFGE8/PLCB1/SLC9A1/SNX31/PSD2/SNX11/SNX33/PLEKHF2/SNX7/AGAP1/OSBPL10/MYO1B/AKT1/PLEKHA4/APOA5/FCHSD2/C8orf44-SGK3/GRK5/CPNE5/SH3PXD2B/SYT15/OSBP/ARHGAP32/MYO1G/OSBPL5/HIP1/BAIAP2L2/SMURF1/MREG/COMMD1/APOC1/RAPGEF6/ARHGAP35/APOC3/PLEKHN1/ANXA10/KCNH1/TPCN1/THY1/MYOF/ARL6/IQGAP2/RUFY4/SYT12/CLVS1/ANXA11/PCLO/SYT4/UNC13A/NUP35/WIPI2/ESYT2/ING2/PICK1/FGD2/PHF12/NR5A1	65
MF	GO:0005085	guanyl-nucleotide exchange factor activity	37/1807	214/17697	0.0009743	0.07409	0.07095	PLEKHG4/ARHGEF16/IQSEC1/TRAPPC3/RIC8B/EPS8L3/RASGRP3/PSD2/MADD/BCR/ECT2L/ARHGEF10L/HERC2/FGD5/DENND3/ARHGEF3/ARHGEF7/ARHGEF12/RINL/MON1A/RGP1/DOCK4/TRIO/DNMBP/ARHGEF25/RAPGEF6/AKAP13/ECT2/RAPGEF1/RAPGEF3/DENND4B/VAV2/DOCK5/DOCK10/EGF/FGD2/RCC2	37
MF	GO:0030674	protein binding, bridging	31/1807	170/17697	0.0009991	0.07409	0.07095	CAV1/NMD3/ARHGAP1/NCK2/SLC9A1/TRIM22/TP53BP2/KHDRBS1/DAB2/VPS18/SH2B2/CUX1/BAIAP2/ANK3/HIP1/PIK3R1/AP2A2/TOB1/SPSB4/LAT/LASP1/FLRT1/FLRT2/ARRB1/STAM/TRDN/GAS2L1/SOCS2/COL14A1/MLPH/MMS19	31
MF	GO:0005201	extracellular matrix structural constituent	30/1807	163/17697	0.001024	0.07409	0.07095	TNXB/FGL2/LTBP2/MFGE8/LUM/ADIPOQ/NID1/ECM1/COL4A2/COL13A1/COL4A1/DCN/COL9A1/COL7A1/COL1A1/PRG4/ZP3/MFAP4/PRELP/VWF/LAMA4/COL15A1/COL5A2/MMRN1/COL4A5/LAMA3/POSTN/FBLN1/HSPG2/COL14A1	30
MF	GO:0005088	Ras guanyl-nucleotide exchange factor activity	26/1807	137/17697	0.00136	0.09225	0.08834	PLEKHG4/ARHGEF16/TRAPPC3/EPS8L3/RASGRP3/MADD/BCR/ECT2L/ARHGEF10L/FGD5/DENND3/ARHGEF3/ARHGEF7/ARHGEF12/RGP1/TRIO/DNMBP/ARHGEF25/AKAP13/ECT2/RAPGEF1/RAPGEF3/DENND4B/VAV2/EGF/FGD2	26
MF	GO:0035257	nuclear hormone receptor binding	28/1807	152/17697	0.001459	0.09315	0.0892	NCOR2/TOB2/RXRA/LRIF1/PPARG/CNOT1/NCOA7/TGFB1I1/CCDC62/ZBTB7A/THRAP3/NR0B1/TCF7L2/MED30/ARRB1/NR4A1/PROX1/PADI2/VDR/TRIP4/PRKCB/HMGA1/GAS2L1/NKX3-1/ACTN4/FLT3/TAF1/MMS19	28
MF	GO:0004713	protein tyrosine kinase activity	25/1807	134/17697	0.002127	0.1282	0.1228	FGFR3/MAP2K5/TNK1/FER/PDGFRB/EPHA6/LCK/ALK/TYRO3/JAK1/PTK2/TNK2/RET/FYN/EPHA3/JAK3/CLK1/BMX/ITK/CSF1R/IGF2R/NTRK3/FLT3/PTK6/MELK	25
MF	GO:0005089	Rho guanyl-nucleotide exchange factor activity	17/1807	79/17697	0.002249	0.1284	0.123	PLEKHG4/ARHGEF16/EPS8L3/BCR/ECT2L/ARHGEF10L/FGD5/ARHGEF3/ARHGEF7/ARHGEF12/TRIO/DNMBP/ARHGEF25/AKAP13/ECT2/VAV2/FGD2	17
MF	GO:0017124	SH3 domain binding	24/1807	130/17697	0.002977	0.1615	0.1546	KHDRBS3/SH3GL1/ARHGAP1/ERRFI1/TP53BP2/KHDRBS1/WIPF3/ENKUR/SYNGAP1/ARHGAP31/NCKIPSD/SIRPA/DOCK4/CBL/AFAP1L1/RAPGEF1/ELMO3/CD2AP/TOM1L1/WAS/GJA1/WASF2/ARHGAP27/PAK3	24
MF	GO:0004674	protein serine/threonine kinase activity	63/1807	439/17697	0.003442	0.1698	0.1626	CAMK2G/NEK10/PRKD3/MAP2K5/CAMKK1/VRK2/AKT3/BCR/CSNK2A1/CDC42BPB/CAMK2A/DAPK2/MAPK12/NEK4/TNIK/AKT1/RIPK1/SPEG/C8orf44-SGK3/TNK2/GRK5/MAP3K6/CAB39/RPS6KL1/CSNK1G2/MAP3K14/PIK3CG/CDK10/CSNK1A1/MAPKAPK3/TRIO/CDK19/MAPK3/CLK1/AKAP13/ROCK1/TGFBR3/TGFBR1/ITPKA/BCKDK/PSKH1/SGK1/CAMK1/STK17B/HUNK/PRKD1/SRPK2/PRKACA/ERN1/MAP3K1/PHKB/PIM1/PRKCB/EIF2AK1/PRKAG3/TAF1/FAM20C/CDC42BPA/MELK/PAK3/WNK2/NEK7/CDKL1	63
MF	GO:0005178	integrin binding	24/1807	132/17697	0.003652	0.1698	0.1626	TNXB/MMP14/TIMP2/MFGE8/ITGB1BP1/FERMT3/ICAM2/CD9/ADAM23/ACTN1/ITGA3/THBS4/ADAMTS8/VWF/ITGB2/SPP1/LAMA3/THY1/GPNMB/ICAM3/ADAM11/ACTN4/ITGB5/CD177	24
MF	GO:0019789	SUMO transferase activity	7/1807	21/17697	0.003661	0.1698	0.1626	ZMIZ2/RNF212/CBX4/NSMCE2/PIAS4/EGR2/ZMIZ1	7
MF	GO:0050839	cell adhesion molecule binding	70/1807	499/17697	0.003756	0.1698	0.1626	TNXB/MMP14/ARVCF/ARHGEF16/SH3GL1/TIMP2/MFGE8/ITGB1BP1/TES/PPFIBP1/ARHGAP1/LRRFIP1/ITGA6/FLNB/FERMT3/ICAM2/PLCB3/FMNL2/CD9/TRIM29/NPTN/YWHAE/VASN/MYO1B/PTPRF/EHD4/ADAM23/ACTN1/ITGA3/BAIAP2/NTNG1/TMOD3/BZW2/EHD1/GPRC5A/THBS4/ANK3/PPP1CA/PCBP1/RPS26/EFHD2/CBL/ADAMTS8/VWF/ITGB2/SPP1/SLC9A3R2/LASP1/LAMA3/POSTN/THY1/SH3GLB2/CD2AP/PUF60/DNAJB1/PDLIM5/GPNMB/NDRG1/PFKP/ICAM3/TBC1D2/ADAM11/AHNAK/ACTN4/PKP1/WASF2/ESYT2/ITGB5/CD177/RPL29	70
MF	GO:0030276	clathrin binding	13/1807	57/17697	0.00421	0.1827	0.1749	SYT8/BIN1/DAB2/SYT15/HIP1/AP2A2/TOM1/NCALD/ARRB1/SYT12/TOM1L1/SYT4/CLTC	13
MF	GO:0061134	peptidase regulator activity	35/1807	219/17697	0.005	0.1967	0.1884	CSTB/TIMP2/CAV1/BIRC7/PYCARD/CST4/NOD1/TNFSF14/TIMP4/SERPINB12/A2M/COL7A1/CTSC/FURIN/CD109/SERPINB2/SPP2/APLP2/SERPINC1/SLPI/SERPINB7/SERPINB13/CSN2/CST2/FBLN1/SERPIND1/ARRB1/SERPINA12/SERPINB5/PI16/CARD18/NKX3-1/ITIH4/CTSH/SPOCK2	35
MF	GO:0038024	cargo receptor activity	17/1807	85/17697	0.005001	0.1967	0.1884	SCARA5/AGER/ENDOU/LOXL2/DAB2/PRG4/HIP1/AP2A2/FOLR1/ITGB2/HHIPL1/ILDR1/ARRB1/CUBN/PGBD1/TMPRSS15/COLEC12	17
MF	GO:0002020	protease binding	23/1807	128/17697	0.005076	0.1967	0.1884	CSTB/PDZD3/BIN1/TIMP2/ADAMTS4/ECM1/PYCARD/TIMP4/ITGA3/A2M/ELANE/STIM1/COL1A1/FURIN/VWF/RFFL/SERPINC1/SERPINB13/DPP4/TRIP4/CARD18/CLTC/CD177	23
MF	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	8/1807	28/17697	0.005581	0.2088	0.1999	SESTD1/PLEKHA4/SH3PXD2B/HIP1/COMMD1/TPCN1/CLVS1/WIPI2	8
MF	GO:0003714	transcription corepressor activity	37/1807	238/17697	0.006293	0.2223	0.2129	LMCD1/LIMD1/NCOR2/TLE6/TOB2/DMAP1/SKOR1/NAB2/TRIM22/RCOR2/ZHX3/ZNF136/SCAI/GPS2/ELANE/ERF/CTCF/BCOR/CRYM/JUNB/HDAC3/TOB1/CBX4/ZBTB7A/ARHGAP35/TDP2/ZFPM2/NR0B1/HR/NANOG/RUNX1T1/DNAJB1/PIAS4/CTBP1/CIR1/ZMYND8/PHF12	37
MF	GO:0046332	SMAD binding	16/1807	80/17697	0.006352	0.2223	0.2129	SKOR1/PRDM16/DAB2/RANBP3/SKIL/TGFB1I1/SMURF1/TOB1/TGFBR3/ZBTB7A/COL5A2/TGFBR1/PAX6/ZC3H3/FOS/SMAD2	16
MF	GO:0030374	nuclear receptor transcription coactivator activity	14/1807	67/17697	0.006954	0.23	0.2202	ZMIZ2/TRERF1/PPARG/ACTN1/NR1I3/NCOA7/CCDC62/THRAP3/MED30/VDR/PRKCB/HMGA1/ACTN4/ZMIZ1	14
MF	GO:0030020	extracellular matrix structural constituent conferring tensile strength	10/1807	41/17697	0.006995	0.23	0.2202	COL4A2/COL13A1/COL4A1/COL9A1/COL7A1/COL1A1/COL15A1/COL5A2/COL4A5/COL14A1	10
MF	GO:0033293	monocarboxylic acid binding	13/1807	64/17697	0.01156	0.3487	0.3339	RXRA/PPARG/CYP26A1/PCCA/APOC1/ACOXL/IGF2R/S100A9/AKR1C2/ACOX2/VDR/CYP27C1/AKR1C1	13
MF	GO:0003779	actin binding	59/1807	431/17697	0.01204	0.3487	0.3339	TMOD4/ENC1/TNNC1/BIN1/MYL3/LDB3/TNS1/SYNPO2L/MYO1D/ARPC2/EPS8L3/FLNB/CAP2/PARVG/MYH1/WIPF3/FMNL2/PKNOX2/INF2/VPS18/FMNL3/MYO1B/MYH13/CORO7/SPTBN5/PTK2/ACTN1/TMOD3/MYO1G/INO80/S100A4/MYO9B/CORO2B/HIP1/MARCKS/PPP1R18/DAAM2/FHOD3/LASP1/VILL/NCALD/CAP1/FMN2/IQGAP2/LSP1/TNNC2/PDLIM5/CACNB2/WIPF2/MYH15/CAPZA3/XIRP1/WASF1/ACTN4/WAS/LMOD3/WASF2/MLPH/PICK1	59
MF	GO:0005516	calmodulin binding	31/1807	200/17697	0.01212	0.3487	0.3339	CAMK2G/PLCB1/CAMKK1/SLC9A1/MYO1D/PLCB3/MYH1/CAMK2A/ENKUR/DAPK2/MYO1B/MYH13/AKT1/MAP6/MYO1G/MAPKAPK3/MYO9B/MARCKS/MAP6D1/FBXL2/MAP2/ITPKA/KCNH1/ARPP21/CAMK1/IQGAP2/RYR3/PHKB/MYH15/UNC13A/CAMSAP1	31
MF	GO:1901981	phosphatidylinositol phosphate binding	26/1807	161/17697	0.01241	0.3487	0.3339	ZFYVE19/SESTD1/SNX27/SDCBP2/PLCB1/SLC9A1/SNX11/MYO1B/AKT1/PLEKHA4/FCHSD2/SH3PXD2B/OSBP/ARHGAP32/MYO1G/OSBPL5/HIP1/COMMD1/PLEKHN1/KCNH1/TPCN1/IQGAP2/RUFY4/CLVS1/WIPI2/FGD2	26
MF	GO:0042974	retinoic acid receptor binding	7/1807	26/17697	0.01317	0.3487	0.3339	NCOR2/LRIF1/PPARG/CNOT1/VDR/HMGA1/ACTN4	7
MF	GO:0019911	structural constituent of myelin sheath	4/1807	10/17697	0.01373	0.3487	0.3339	PLLP/MARVELD1/PLP1/CMTM8	4
MF	GO:0035615	clathrin adaptor activity	4/1807	10/17697	0.01373	0.3487	0.3339	DAB2/HIP1/AP2A2/ARRB1	4
MF	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	4/1807	10/17697	0.01373	0.3487	0.3339	PIK3R1/CBL/FBXL2/PTPN13	4
MF	GO:0098748	endocytic adaptor activity	4/1807	10/17697	0.01373	0.3487	0.3339	DAB2/HIP1/AP2A2/ARRB1	4
MF	GO:0044548	S100 protein binding	5/1807	15/17697	0.01382	0.3487	0.3339	AGER/ATP2A2/KCNK3/ANXA11/AHNAK	5
MF	GO:0005154	epidermal growth factor receptor binding	8/1807	33/17697	0.01577	0.3871	0.3707	HBEGF/FER/TNK2/HIP1/CBL/ATXN2/VAV2/EGF	8
MF	GO:0035091	phosphatidylinositol binding	36/1807	245/17697	0.0163	0.3871	0.3707	ZFYVE19/SESTD1/SNX27/SDCBP2/PLCB1/SLC9A1/SNX31/SNX11/SNX33/PLEKHF2/SNX7/MYO1B/AKT1/PLEKHA4/FCHSD2/C8orf44-SGK3/SH3PXD2B/OSBP/ARHGAP32/MYO1G/OSBPL5/HIP1/MREG/COMMD1/PLEKHN1/KCNH1/TPCN1/THY1/IQGAP2/RUFY4/CLVS1/WIPI2/ESYT2/ING2/FGD2/PHF12	36
MF	GO:0030414	peptidase inhibitor activity	28/1807	182/17697	0.01808	0.3871	0.3707	CSTB/TIMP2/BIRC7/CST4/TNFSF14/TIMP4/SERPINB12/A2M/COL7A1/FURIN/CD109/SERPINB2/SPP2/APLP2/SERPINC1/SLPI/SERPINB7/SERPINB13/CSN2/CST2/SERPIND1/ARRB1/SERPINA12/SERPINB5/PI16/CARD18/ITIH4/SPOCK2	28
MF	GO:0005229	intracellular calcium activated chloride channel activity	5/1807	16/17697	0.01844	0.3871	0.3707	ANO5/ANO7/CLCA4/TTYH3/ANO10	5
MF	GO:0022841	potassium ion leak channel activity	5/1807	16/17697	0.01844	0.3871	0.3707	KCNK7/KCNK15/KCNK17/KCNK3/KCNK12	5
MF	GO:0061778	intracellular chloride channel activity	5/1807	16/17697	0.01844	0.3871	0.3707	ANO5/ANO7/CLCA4/TTYH3/ANO10	5
MF	GO:0048306	calcium-dependent protein binding	12/1807	61/17697	0.01904	0.3871	0.3707	SYT8/TNNC1/SLC9A1/MYO1D/PEF1/A2M/S100A4/SNAP25/PDCD6IP/TNNC2/ANXA11/CD177	12
MF	GO:0004866	endopeptidase inhibitor activity	27/1807	175/17697	0.01932	0.3871	0.3707	CSTB/TIMP2/BIRC7/CST4/TNFSF14/TIMP4/SERPINB12/A2M/COL7A1/FURIN/CD109/SERPINB2/SPP2/APLP2/SERPINC1/SLPI/SERPINB7/SERPINB13/CSN2/CST2/SERPIND1/ARRB1/SERPINA12/SERPINB5/CARD18/ITIH4/SPOCK2	27
MF	GO:0004683	calmodulin-dependent protein kinase activity	7/1807	28/17697	0.0198	0.3871	0.3707	CAMK2G/CAMKK1/CAMK2A/MAPKAPK3/ITPKA/CAMK1/PHKB	7
MF	GO:0030507	spectrin binding	7/1807	28/17697	0.0198	0.3871	0.3707	PTPRN/SPTBN5/ANK3/USH1G/KIF3A/DCTN2/CAMSAP1	7
MF	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	4/1807	11/17697	0.01986	0.3871	0.3707	PADI1/AGMAT/PADI4/PADI2	4
MF	GO:0070411	I-SMAD binding	4/1807	11/17697	0.01986	0.3871	0.3707	TGFB1I1/SMURF1/TGFBR1/SMAD2	4
MF	GO:0051219	phosphoprotein binding	15/1807	83/17697	0.01998	0.3871	0.3707	NCK2/SAG/YWHAE/LCK/RRAGA/PIK3R1/CBL/MAPK3/CBX4/ARR3/THRAP3/VAV2/IGF2R/ARRB1/PIK3R3	15
MF	GO:1901681	sulfur compound binding	36/1807	250/17697	0.02166	0.4123	0.3948	TNXB/MMACHC/LTBP2/HBEGF/TPMT/CLEC3B/COL13A1/PTGES2/LIPG/CBS/PTPRF/ACADVL/APOA5/ELANE/THBS4/PCCA/ACOT12/PRELP/CD34/ADAMTS8/TGFBR3/PGF/SUV39H2/APLP2/SERPINC1/POSTN/CRISPLD2/SOD3/MSTN/ACOT11/SERPIND1/SOST/TPK1/GPNMB/RTN4R/RPL29	36
MF	GO:0005501	retinoid binding	8/1807	35/17697	0.02228	0.4127	0.3952	RXRA/RBP4/CYP26A1/IGF2R/RBP5/CYP27C1/OPN4/ADH7	8
MF	GO:0035035	histone acetyltransferase binding	7/1807	29/17697	0.02387	0.4127	0.3952	MTF1/CREB1/TAF7L/EGR1/ZBTB7A/PAX6/TRIP4	7
MF	GO:0017081	chloride channel regulator activity	5/1807	17/17697	0.02398	0.4127	0.3952	SLC9A3R1/C8orf44-SGK3/SGK1/WNK2/CFTR	5
MF	GO:0003713	transcription coactivator activity	44/1807	319/17697	0.02416	0.4127	0.3952	NFE2L3/HTATIP2/RXRA/ZMIZ2/PRDM16/MTF1/SERTAD2/TRERF1/TAF7L/SMARCD1/PPARG/PMF1/SMARCD2/ACTN1/GPS2/ELF3/NR1I3/NCOA7/TGFB1I1/JUNB/ACTL6B/CCDC62/TAF5L/THRAP3/ZFPM2/NEUROD1/MED30/WBP2NL/SUB1/SS18L2/VDR/TRIP4/TAF4/GMEB1/PRKCB/HMGA1/ACTN4/TAF1/NPM1/GMEB2/MMS19/NR2C2/ZMIZ1/NR5A1	44
MF	GO:0015108	chloride transmembrane transporter activity	17/1807	100/17697	0.02433	0.4127	0.3952	FXYD3/SLC4A1/BEST1/APOL1/GLRA2/ANO5/SLC22A1/ANO7/CLCNKA/GABRR3/SLC12A1/SLC12A8/CLCA4/TTYH3/ANO10/CLCN5/CFTR	17
MF	GO:0003707	steroid hormone receptor activity	11/1807	56/17697	0.02442	0.4127	0.3952	RXRA/PPARG/PAQR7/NR1I3/NR0B1/NR4A1/VDR/NR2F6/NKX3-1/NR2C2/NR5A1	11
MF	GO:0043621	protein self-association	11/1807	56/17697	0.02442	0.4127	0.3952	PPARG/RNF112/SLC9A3R1/SLC2A1/SPTBN5/CTSC/TMEM43/ATXN1/NKX3-1/FLT3/SVIP	11
MF	GO:0070412	R-SMAD binding	6/1807	23/17697	0.02472	0.4127	0.3952	RANBP3/SMURF1/PAX6/ZC3H3/FOS/SMAD2	6
MF	GO:0019840	isoprenoid binding	8/1807	36/17697	0.02616	0.43	0.4118	RXRA/RBP4/CYP26A1/IGF2R/RBP5/CYP27C1/OPN4/ADH7	8
MF	GO:0004712	protein serine/threonine/tyrosine kinase activity	9/1807	43/17697	0.02732	0.4357	0.4172	MAP2K5/AKT1/TNK2/MAPKAPK3/MAPK3/CLK1/SGK1/PRKACA/PAK3	9
MF	GO:0017154	semaphorin receptor activity	4/1807	12/17697	0.02743	0.4357	0.4172	PLXNC1/PLXNB2/PLXNA2/PLXND1	4
MF	GO:0098632	cell-cell adhesion mediator activity	10/1807	50/17697	0.02771	0.4357	0.4172	TRIM29/NPTN/NFASC/BAIAP2/NTNG1/TMOD3/PPP1CA/SIRPA/CNTN6/PDLIM5	10
MF	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	7/1807	30/17697	0.02847	0.4413	0.4226	SESTD1/AKT1/PLEKHA4/FCHSD2/MYO1G/HIP1/COMMD1	7
MF	GO:0099106	ion channel regulator activity	19/1807	118/17697	0.03021	0.4585	0.439	FXYD3/PDZD3/CAV1/SCN1B/KCNS1/SCN3B/GNB2/YWHAE/C8orf44-SGK3/STIM1/CAV3/KCNS3/CRISP1/SGK1/PRKCB/CACNG7/FXYD2/WNK2/CFTR	19
MF	GO:0061135	endopeptidase regulator activity	27/1807	182/17697	0.03043	0.4585	0.439	CSTB/TIMP2/BIRC7/CST4/TNFSF14/TIMP4/SERPINB12/A2M/COL7A1/FURIN/CD109/SERPINB2/SPP2/APLP2/SERPINC1/SLPI/SERPINB7/SERPINB13/CSN2/CST2/SERPIND1/ARRB1/SERPINA12/SERPINB5/CARD18/ITIH4/SPOCK2	27
MF	GO:0070851	growth factor receptor binding	21/1807	134/17697	0.03085	0.4585	0.439	HBEGF/ECM1/FER/PYCARD/PDGFRB/NPTN/SLC9A3R1/TNK2/FYN/HIP1/CBL/ATXN2/TOLLIP/PGF/CD2AP/VAV2/IL12B/FLRT1/FLRT2/ERN1/EGF	21
MF	GO:0018024	histone-lysine N-methyltransferase activity	9/1807	44/17697	0.03134	0.4595	0.44	PRDM16/SETMAR/DOT1L/SMYD2/SETD7/SUV39H2/PRDM7/SETD1A/WDR82	9
MF	GO:0005070	SH3/SH2 adaptor activity	10/1807	52/17697	0.03547	0.4965	0.4755	ARHGAP1/NCK2/TP53BP2/KHDRBS1/SH2B2/TOB1/LAT/LASP1/STAM/SOCS2	10
MF	GO:0043495	protein membrane anchor	4/1807	13/17697	0.03649	0.4965	0.4755	SLC4A1/NUP153/RAPSN/SUN5	4
MF	GO:0008201	heparin binding	25/1807	169/17697	0.03727	0.4965	0.4755	TNXB/LTBP2/HBEGF/CLEC3B/COL13A1/LIPG/PTPRF/APOA5/ELANE/THBS4/PRELP/ADAMTS8/TGFBR3/PGF/APLP2/SERPINC1/POSTN/CRISPLD2/SOD3/MSTN/SERPIND1/SOST/GPNMB/RTN4R/RPL29	25
MF	GO:0016505	peptidase activator activity involved in apoptotic process	5/1807	19/17697	0.03798	0.4965	0.4755	PYCARD/NOD1/CTSC/NKX3-1/CTSH	5
MF	GO:0022840	leak channel activity	5/1807	19/17697	0.03798	0.4965	0.4755	KCNK7/KCNK15/KCNK17/KCNK3/KCNK12	5
MF	GO:0022842	narrow pore channel activity	5/1807	19/17697	0.03798	0.4965	0.4755	KCNK7/KCNK15/KCNK17/KCNK3/KCNK12	5
MF	GO:0031690	adrenergic receptor binding	5/1807	19/17697	0.03798	0.4965	0.4755	SH3GL1/SLC9A3R1/ARRB2/ARRB1/GNAS	5
MF	GO:0070300	phosphatidic acid binding	5/1807	19/17697	0.03798	0.4965	0.4755	SESTD1/GRAMD1B/COMMD1/RAPGEF6/PLEKHN1	5
MF	GO:0098641	cadherin binding involved in cell-cell adhesion	5/1807	19/17697	0.03798	0.4965	0.4755	TRIM29/BAIAP2/TMOD3/PPP1CA/PDLIM5	5
MF	GO:0005254	chloride channel activity	13/1807	75/17697	0.0393	0.503	0.4816	FXYD3/BEST1/APOL1/GLRA2/ANO5/ANO7/CLCNKA/GABRR3/CLCA4/TTYH3/ANO10/CLCN5/CFTR	13
MF	GO:0005080	protein kinase C binding	10/1807	53/17697	0.03987	0.503	0.4816	HDAC5/LDB3/AVPR1A/AKT1/GRK5/MARCKS/ADCY4/PDLIM5/PRKCB/PICK1	10
MF	GO:0005544	calcium-dependent phospholipid binding	10/1807	53/17697	0.03987	0.503	0.4816	PLA2G4B/SYT8/CPNE5/SYT15/ANXA10/SYT12/ANXA11/PCLO/SYT4/ESYT2	10
MF	GO:0032266	phosphatidylinositol-3-phosphate binding	8/1807	39/17697	0.04055	0.5049	0.4834	ZFYVE19/SESTD1/SNX27/PLEKHA4/SH3PXD2B/HIP1/RUFY4/WIPI2	8
MF	GO:0008022	protein C-terminus binding	27/1807	187/17697	0.04095	0.5049	0.4834	PDZD3/SDCBP2/SH3GL1/PPP1CC/ECM1/DAB2/PPARG/LCK/BAIAP2/SYNJ2BP/CAV3/ATXN2/SLC9A3R2/KCNK3/HIC2/TAX1BP3/ATXN1/NCF2/YEATS4/SIAH1/CD2AP/FBLN1/HSPG2/DYNLT1/PIAS4/CTBP1/PICK1	27