ONTOLOGY	ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	qvalue	geneID	Count
KEGG	hsa04510	Focal adhesion	48/868	201/8144	4.372e-08	1.429e-05	1.035e-05	TNXB/ITGA9/CAV1/PPP1CC/ITGA6/FLNB/COL4A2/PIP5K1C/PARVG/AKT3/ACTG1/COL4A1/PDGFRB/CAPN2/AKT1/ARHGAP5/PTK2/COL9A1/ACTN1/ITGA3/THBS4/FYN/COL1A1/PPP1CA/MYL5/CAV3/PIK3R1/VWF/MAPK3/LAMA4/SPP1/ROCK1/PGF/ARHGAP35/COL4A5/LAMA3/ITGA7/RAPGEF1/VAV2/PIK3CB/CHAD/EGF/PRKCB/PIK3R3/ACTN4/CDC42/PAK3/ITGB5	48
KEGG	hsa04926	Relaxin signaling pathway	33/868	129/8144	1.115e-06	0.0001823	0.000132	ADCY9/PLCB1/CREB1/COL4A2/GNG4/PLCB3/AKT3/GNB2/COL4A1/MAPK12/AKT1/RLN3/CREB3L2/GNB4/GNG10/PLCB4/COL1A1/CREB5/ADCY5/PIK3R1/MAPK3/ARRB2/TGFBR1/COL4A5/ADCY4/PRKACA/ARRB1/RLN2/PIK3CB/FOS/SMAD2/PIK3R3/GNAS	33
KEGG	hsa04928	Parathyroid hormone synthesis, secretion and action	28/868	106/8144	3.674e-06	0.0003239	0.0002346	MMP14/ADCY9/HBEGF/PLCB1/RXRA/CREB1/PLCB3/GNA11/CDKN1A/MEF2D/CREB3L2/SLC9A3R1/EGR1/PLCB4/CREB5/ADCY5/MAPK3/ARRB2/AKAP13/ADCY4/PRKACA/ARRB1/SOST/FOS/VDR/LRP5/PRKCB/GNAS	28
KEGG	hsa04611	Platelet activation	31/868	124/8144	3.962e-06	0.0003239	0.0002346	PLA2G4B/ADCY9/PLCB1/PPP1CC/FERMT3/PLCB3/AKT3/ACTG1/MAPK12/AKT1/F2RL3/ARHGEF12/STIM1/PLCB4/PIK3CG/FYN/COL1A1/PPP1CA/ADCY5/PIK3R1/VWF/MAPK3/ROCK1/GP5/ARHGAP35/ADCY4/PRKACA/PIK3CB/PIK3R3/GNAS/GP6	31
KEGG	hsa04925	Aldosterone synthesis and secretion	26/868	98/8144	7.46e-06	0.0004157	0.0003011	CAMK2G/ADCY9/PRKD3/PLCB1/CREB1/PLCB3/GNA11/CAMK2A/CREB3L2/CYP11A1/DAGLA/PLCB4/CREB5/ADCY5/LIPE/KCNK3/CYP21A2/CAMK1/PRKD1/ADCY4/PRKACA/NR4A1/NPPA/PRKCB/GNAS/POMC	26
KEGG	hsa04927	Cortisol synthesis and secretion	20/868	65/8144	7.627e-06	0.0004157	0.0003011	ADCY9/PLCB1/CREB1/PLCB3/GNA11/PDE8A/CREB3L2/CYP11A1/PLCB4/CREB5/ADCY5/KCNK3/CYP21A2/NR0B1/ADCY4/PRKACA/NR4A1/GNAS/POMC/NR5A1	20
KEGG	hsa04935	Growth hormone synthesis, secretion and action	28/868	119/8144	3.84e-05	0.001493	0.001082	ADCY9/PLCB1/CREB1/PLCB3/AKT3/GNA11/MAPK12/AKT1/CREB3L2/STAT5A/PTK2/GHR/PLCB4/CREB5/ADCY5/PIK3R1/JUNB/MAPK3/PLCG1/ADCY4/PRKACA/PIK3CB/FOS/MAP3K1/PRKCB/PIK3R3/GNAS/SOCS2	28
KEGG	hsa04725	Cholinergic synapse	27/868	113/8144	3.94e-05	0.001493	0.001082	CAMK2G/ADCY9/PLCB1/CREB1/GNG4/PLCB3/AKT3/GNA11/GNB2/CAMK2A/AKT1/CREB3L2/GNB4/GNG10/PLCB4/PIK3CG/FYN/CREB5/ADCY5/PIK3R1/MAPK3/ADCY4/PRKACA/PIK3CB/FOS/PRKCB/PIK3R3	27
KEGG	hsa04728	Dopaminergic synapse	30/868	132/8144	4.157e-05	0.001493	0.001082	CAMK2G/PLCB1/PPP1CC/CREB1/GNG4/PLCB3/COMT/AKT3/GNB2/CAMK2A/MAPK12/AKT1/CREB3L2/GNB4/KCNJ9/GNG10/PLCB4/PPP1CA/CREB5/ADCY5/TH/ARRB2/PPP2R5C/PRKACA/ARRB1/FOS/PRKCB/GNAS/MAOA/GRIA1	30
KEGG	hsa05205	Proteoglycans in cancer	41/868	205/8144	4.566e-05	0.001493	0.001082	CAMK2G/WNT3/CAV1/HBEGF/LUM/PPP1CC/SLC9A1/FLNB/AKT3/CDKN1A/ACTG1/CAMK2A/DCN/MAPK12/RRAS2/AKT1/PTK2/ARHGEF12/ANK3/COL1A1/PPP1CA/CAV3/PIK3R1/CBL/MAPK3/ROCK1/PLCG1/NANOG/VAV2/IL12B/PRKACA/PIK3CB/HSPG2/FZD2/MYC/PRKCB/SMAD2/PIK3R3/CDC42/ITGB5/FZD1	41
KEGG	hsa04750	Inflammatory mediator regulation of TRP channels	24/868	98/8144	6.873e-05	0.002043	0.00148	PLA2G4B/CAMK2G/ADCY9/PLCB1/PPP1CC/PLCB3/CAMK2A/MAPK12/TRPV3/P2RY2/PTGER4/HRH1/PLCB4/PPP1CA/ADCY5/PIK3R1/TRPM8/PLCG1/ADCY4/PRKACA/PIK3CB/PRKCB/PIK3R3/GNAS	24
KEGG	hsa04261	Adrenergic signaling in cardiomyocytes	32/868	150/8144	8.661e-05	0.00236	0.001709	CAMK2G/TNNC1/MYL3/ADCY9/PLCB1/PPP1CC/SCN1B/SLC9A1/ATP2A2/CREB1/PLCB3/CACNB1/AKT3/CAMK2A/MAPK12/AKT1/CREB3L2/PLCB4/PIK3CG/PPP1CA/CREB5/ADCY5/MAPK3/CACNA2D1/RAPGEF3/PPP2R5C/ADCY4/PRKACA/CACNB2/CACNG7/GNAS/FXYD2	32
KEGG	hsa04371	Apelin signaling pathway	30/868	139/8144	0.0001144	0.002879	0.002085	MYL3/ADCY9/HDAC5/PLCB1/SLC9A1/MAP1LC3B2/GNG4/PLCB3/AKT3/GNB2/MEF2D/RRAS2/AKT1/GNB4/GNG10/EGR1/KLF2/PLIN1/PLCB4/PIK3CG/ADCY5/LIPE/MAPK3/SPP1/TGFBR1/ADCY4/PRKACA/RYR3/SMAD2/PRKAG3	30
KEGG	hsa04921	Oxytocin signaling pathway	32/868	154/8144	0.0001462	0.003414	0.002473	PLA2G4B/CAMK2G/ADCY9/PLCB1/PPP1CC/MAP2K5/PLCB3/CACNB1/CDKN1A/ACTG1/CAMK2A/NFATC3/KCNJ9/PLCB4/PIK3CG/PPP1CA/ADCY5/MAPK3/ROCK1/CACNA2D1/PPP3R2/CAMK1/ADCY4/PRKACA/FOS/CACNB2/NPPA/RYR3/PRKCB/CACNG7/GNAS/PRKAG3	32
KEGG	hsa04015	Rap1 signaling pathway	40/868	210/8144	0.0001718	0.003746	0.002713	FGFR3/ADCY9/PRKD3/PLCB1/SIPA1L1/RASGRP3/PLCB3/AKT3/ACTG1/PDGFRB/MAPK12/CSF1/AKT1/F2RL3/ANGPT1/PLCB4/DOCK4/ADCY5/PIK3R1/MAPK3/ITGB2/RAPGEF6/PGF/ADORA2A/PLCG1/LAT/RAPGEF1/RAPGEF3/RAP1GAP/PRKD1/ADCY4/VAV2/CSF1R/PIK3CB/EGF/PRKCB/PIK3R3/GNAS/CDC42/FPR1	40
KEGG	hsa04911	Insulin secretion	21/868	86/8144	0.0002011	0.004109	0.002976	CAMK2G/ADCY9/PLCB1/CREB1/PLCB3/GNA11/CAMK2A/CREB3L2/SLC2A1/PLCB4/CREB5/ADCY5/SNAP25/ADCY4/KCNU1/PRKACA/RIMS2/PCLO/PRKCB/GNAS/FXYD2	21
KEGG	hsa05031	Amphetamine addiction	18/868	69/8144	0.0002342	0.004505	0.003263	CAMK2G/PPP1CC/GRIN2C/CREB1/CAMK2A/CREB3L2/PPP1CA/CREB5/ADCY5/TH/PPP3R2/PRKACA/FOS/PRKCB/GRIN3B/GNAS/MAOA/GRIA1	18
KEGG	hsa04933	AGE-RAGE signaling pathway in diabetic complications	23/868	100/8144	0.0002651	0.004815	0.003488	AGER/PLCB1/COL4A2/PLCB3/AKT3/COL4A1/MAPK12/AKT1/STAT5A/EGR1/PLCB4/COL1A1/PIK3R1/MAPK3/TGFBR1/PLCG1/COL4A5/PIK3CB/PIM1/PRKCB/SMAD2/PIK3R3/CDC42	23
KEGG	hsa05146	Amoebiasis	23/868	102/8144	0.0003602	0.005938	0.0043	PLCB1/COL4A2/PLCB3/GNA11/COL4A1/C8A/PTK2/ACTN1/PLCB4/COL1A1/PIK3R1/ITGB2/LAMA4/COL4A5/LAMA3/SERPINB13/IL12B/PRKACA/PIK3CB/PRKCB/PIK3R3/GNAS/ACTN4	23
KEGG	hsa04072	Phospholipase D signaling pathway	30/868	148/8144	0.0003662	0.005938	0.0043	PLA2G4B/ADCY9/PLCB1/AGPAT4/PIP5K1C/PLCB3/AKT3/AVPR1A/PDGFRB/RRAS2/AKT1/AGPAT3/DGKZ/PLCB4/PIK3CG/FYN/ADCY5/PIK3R1/MAPK3/DGKE/PLCG1/RAPGEF3/GRM8/ADCY4/PIK3CB/TSC2/EGF/PIK3R3/GNAS/ARF1	30
KEGG	hsa05163	Human cytomegalovirus infection	41/868	225/8144	0.0003813	0.005938	0.0043	TRAF5/ADCY9/PLCB1/CREB1/GNG4/PLCB3/AKT3/GNA11/CDKN1A/GNB2/MAPK12/AKT1/CREB3L2/RIPK1/NFATC3/JAK1/PTK2/GNB4/ARHGEF12/GNG10/PTGER4/PLCB4/BID/PTGER1/CCR3/CREB5/ADCY5/PIK3R1/MAPK3/AKAP13/ROCK1/PPP3R2/ADCY4/PRKACA/PIK3CB/TSC2/MYC/PRKCB/PIK3R3/GNAS/TNFRSF1A	41
KEGG	hsa04713	Circadian entrainment	22/868	97/8144	0.0004406	0.006549	0.004744	CAMK2G/ADCY9/PLCB1/GRIN2C/CREB1/GNG4/PLCB3/GNB2/CAMK2A/GNB4/KCNJ9/GNG10/PLCB4/ADCY5/MAPK3/ADCY4/PRKACA/FOS/RYR3/PRKCB/GNAS/GRIA1	22
KEGG	hsa04151	PI3K-Akt signaling pathway	58/868	354/8144	0.0004991	0.007096	0.005139	TNXB/FGFR3/ITGA9/CRTC2/RXRA/ITGA6/CREB1/COL4A2/GNG4/AKT3/CDKN1A/GNB2/COL4A1/PDGFRB/YWHAE/CSF1/AKT1/CREB3L2/C8orf44-SGK3/JAK1/PTK2/COL9A1/GNB4/ITGA3/GNG10/GHR/PCK2/ANGPT1/THBS4/PIK3CG/COL1A1/PRL/CREB5/PIK3R1/VWF/MAPK3/JAK3/LAMA4/SPP1/PGF/COL4A5/LAMA3/ITGA7/SGK1/MCL1/PHLPP2/PPP2R5C/CSF1R/PIK3CB/TSC2/NR4A1/CHAD/MYC/EGF/PIK3R3/FLT3/ITGB5/NTF3	58
KEGG	hsa04923	Regulation of lipolysis in adipocytes	15/868	56/8144	0.0005625	0.007664	0.005551	ADCY9/AKT3/AKT1/PLIN1/ADCY5/PIK3R1/LIPE/ADCY4/PRKACA/PIK3CB/NPPA/PNPLA2/PIK3R3/GNAS/AQP7	15
KEGG	hsa04512	ECM-receptor interaction	20/868	88/8144	0.0007681	0.009863	0.007144	TNXB/ITGA9/ITGA6/COL4A2/COL4A1/COL9A1/ITGA3/THBS4/COL1A1/VWF/LAMA4/SPP1/GP5/COL4A5/LAMA3/ITGA7/CHAD/HSPG2/ITGB5/GP6	20
KEGG	hsa04670	Leukocyte transendothelial migration	24/868	114/8144	0.0007842	0.009863	0.007144	CLDN16/CLDN15/ACTG1/MAPK12/ARHGAP5/PTK2/ACTN1/MYL5/PIK3R1/ITGB2/PECAM1/ROCK1/ARHGAP35/PLCG1/NCF2/ITK/THY1/RAPGEF3/VAV2/PIK3CB/PRKCB/PIK3R3/ACTN4/CDC42	24
KEGG	hsa05135	Yersinia infection	27/868	137/8144	0.001108	0.01311	0.009493	ARPC2/PIP5K1C/AKT3/PYCARD/WIPF3/ACTG1/MAPK12/AKT1/LCK/NFATC3/PTK2/ARHGEF7/ARHGEF12/BAIAP2/PIK3R1/MAPK3/ROCK1/PLCG1/LAT/VAV2/PIK3CB/FOS/WIPF2/PIK3R3/WAS/CDC42/WASF2	27
KEGG	hsa04666	Fc gamma R-mediated phagocytosis	21/868	97/8144	0.001122	0.01311	0.009493	PLA2G4B/BIN1/ARPC2/PIP5K1C/AKT3/AKT1/ASAP2/PIK3R1/MAPK3/MARCKS/ASAP3/PLCG1/LAT/VAV2/PIK3CB/PRKCB/WASF1/PIK3R3/WAS/CDC42/WASF2	21
KEGG	hsa04012	ErbB signaling pathway	19/868	85/8144	0.001274	0.01436	0.0104	CAMK2G/HBEGF/NCK2/AKT3/CDKN1A/CAMK2A/AKT1/STAT5A/PTK2/PIK3R1/CBL/MAPK3/PLCG1/PIK3CB/MYC/EGF/PRKCB/PIK3R3/PAK3	19
KEGG	hsa04912	GnRH signaling pathway	20/868	93/8144	0.00159	0.01733	0.01255	PLA2G4B/MMP14/CAMK2G/ADCY9/HBEGF/PLCB1/PLCB3/GNA11/CAMK2A/MAPK12/EGR1/PLCB4/ADCY5/MAPK3/ADCY4/PRKACA/MAP3K1/PRKCB/GNAS/CDC42	20
KEGG	hsa04919	Thyroid hormone signaling pathway	24/868	121/8144	0.001868	0.01916	0.01388	PLCB1/RXRA/SLC9A1/ATP2A2/PLCB3/AKT3/ACTG1/MED13L/AKT1/SLC2A1/PLCB4/PIK3R1/HDAC3/MAPK3/PLCG1/MED30/PRKACA/PIK3CB/TSC2/PFKP/MYC/PRKCB/PIK3R3/FXYD2	24
KEGG	hsa04916	Melanogenesis	21/868	101/8144	0.00192	0.01916	0.01388	CAMK2G/MITF/WNT3/ADCY9/PLCB1/CREB1/PLCB3/CAMK2A/CREB3L2/TCF7L1/PLCB4/ADCY5/MAPK3/ADCY4/TCF7L2/PRKACA/FZD2/PRKCB/GNAS/POMC/FZD1	21
KEGG	hsa04062	Chemokine signaling pathway	34/868	192/8144	0.001934	0.01916	0.01388	ADCY9/CCL26/PLCB1/GNG4/PLCB3/AKT3/GNB2/AKT1/PTK2/GNB4/GRK5/GNG10/PLCB4/PIK3CG/CCR3/ADCY5/PIK3R1/MAPK3/JAK3/ARRB2/ROCK1/PLCG1/ITK/ADCY4/VAV2/CXCL14/PRKACA/ARRB1/PIK3CB/CXCR3/PRKCB/PIK3R3/WAS/CDC42	34
KEGG	hsa05166	Human T-cell leukemia virus 1 infection	38/868	222/8144	0.002044	0.01966	0.01424	BUB3/ADCY9/CRTC2/CREB1/HLA-DOB/AKT3/CDKN1A/AKT1/CREB3L2/LCK/SLC2A1/RANBP3/NFATC3/JAK1/STAT5A/GPS2/EGR1/MAP3K14/CREB5/ADCY5/PIK3R1/ELK4/MAPK3/JAK3/ITGB2/TGFBR1/MAD1L1/PPP3R2/ADCY4/PRKACA/PIK3CB/FOS/MAP3K1/MYC/SMAD2/PIK3R3/TNFRSF1A/EGR2	38
KEGG	hsa04066	HIF-1 signaling pathway	22/868	109/8144	0.002257	0.02109	0.01527	CAMK2G/HMOX1/LDHB/AKT3/CDKN1A/CAMK2A/PGK1/AKT1/SLC2A1/ANGPT1/PIK3R1/MAPK3/CUL2/PLCG1/PIK3CB/EGLN2/PFKP/NPPA/EGF/PRKCB/LDHAL6B/PIK3R3	22
KEGG	hsa05230	Central carbon metabolism in cancer	16/868	70/8144	0.002353	0.02137	0.01548	FGFR3/LDHB/AKT3/PDGFRB/AKT1/SLC2A1/RET/PIK3R1/MAPK3/PIK3CB/NTRK3/PFKP/MYC/LDHAL6B/PIK3R3/FLT3	16
KEGG	hsa04929	GnRH secretion	15/868	64/8144	0.002454	0.02169	0.01571	PLCB1/PLCB3/AKT3/GNA11/AKT1/KCNJ9/PLCB4/PIK3R1/MAPK3/SPP1/ARRB2/ARRB1/PIK3CB/PRKCB/PIK3R3	15
KEGG	hsa04020	Calcium signaling pathway	40/868	240/8144	0.002613	0.02249	0.01629	PPIF/CAMK2G/FGFR3/TNNC1/ADCY9/P2RX7/PLCB1/ATP2A2/GRIN2C/PLCB3/GNA11/AVPR1A/PDGFRB/CAMK2A/STIM1/HRH1/RET/PLCB4/PTGER1/HRH2/ADORA2A/CYSLTR2/ITPKA/TPCN1/PLCG1/PPP3R2/CAMK1/ADCY4/ASPH/PRKACA/P2RX3/P2RX5/TNNC2/NTRK3/TRDN/RYR3/PHKB/EGF/PRKCB/GNAS	40
KEGG	hsa04520	Adherens junction	16/868	71/8144	0.002745	0.02301	0.01667	FER/ACTG1/CSNK2A1/PTPRF/TCF7L1/ACTN1/BAIAP2/FYN/MAPK3/TGFBR1/TCF7L2/WASF1/ACTN4/WAS/CDC42/WASF2	16
KEGG	hsa04370	VEGF signaling pathway	14/868	59/8144	0.002992	0.02384	0.01727	PLA2G4B/AKT3/MAPK12/AKT1/PTK2/MAPKAPK3/PIK3R1/MAPK3/PLCG1/PPP3R2/PIK3CB/PRKCB/PIK3R3/CDC42	14
KEGG	hsa04973	Carbohydrate digestion and absorption	12/868	47/8144	0.003052	0.02384	0.01727	PLCB1/PLCB3/AKT3/AKT1/PLCB4/PIK3R1/TAS1R3/MGAM/PIK3CB/PRKCB/PIK3R3/FXYD2	12
KEGG	hsa05231	Choline metabolism in cancer	20/868	98/8144	0.003063	0.02384	0.01727	PLA2G4B/PIP5K1C/AKT3/PDGFRB/AKT1/SLC22A1/DGKZ/PIK3R1/MAPK3/DGKE/PLCG1/PIK3CB/FOS/TSC2/EGF/PRKCB/WASF1/PIK3R3/WAS/WASF2	20
KEGG	hsa04144	Endocytosis	41/868	251/8144	0.003386	0.02478	0.01795	FGFR3/RAB31/RAB11FIP4/BIN1/SH3GL1/STAM2/CAV1/IQSEC1/ARPC2/ACAP3/PIP5K1C/PSD2/WIPF3/DAB2/AGAP1/EHD4/GRK5/RAB11FIP5/EHD1/ASAP2/CAV3/SMURF1/CBL/AP2A2/FOLR1/ASAP3/ARRB2/PDCD6IP/TGFBR1/SH3GLB2/IGF2R/ARRB1/STAM/WIPF2/RNF103-CHMP3/CAPZA3/SMAD2/CLTC/CDC42/ARF1/ARFGAP1	41
KEGG	hsa04630	JAK-STAT signaling pathway	29/868	162/8144	0.003419	0.02478	0.01795	IL17D/STAM2/AKT3/CDKN1A/PDGFRB/IL12RB2/AKT1/JAK1/STAT5A/IL24/GHR/PRL/PIK3R1/JAK3/IL27RA/CNTFR/IL22RA1/MCL1/LEP/IL12B/PIK3CB/STAM/MYC/EGF/PIM1/PIK3R3/PIAS4/SOCS2/IL19	29
KEGG	hsa04024	cAMP signaling pathway	37/868	221/8144	0.003435	0.02478	0.01795	CAMK2G/ADCY9/PPP1CC/SLC9A1/ATP2A2/GRIN2C/CREB1/AKT3/CAMK2A/HCAR2/RRAS2/AKT1/CREB3L2/PPP1CA/CREB5/ADCY5/PIK3R1/LIPE/MAPK3/ROCK1/ADORA2A/HTR1D/RAPGEF3/ADCY4/VAV2/PRKACA/PIK3CB/FOS/NPPA/GRIN3B/EDN2/PIK3R3/GNAS/POMC/GRIA1/FXYD2/CFTR	37
KEGG	hsa04934	Cushing syndrome	28/868	155/8144	0.003486	0.02478	0.01795	CAMK2G/WNT3/ADCY9/PLCB1/CREB1/PLCB3/GNA11/CDKN1A/CAMK2A/PDE8A/CREB3L2/CYP11A1/TCF7L1/PLCB4/CREB5/ADCY5/MAPK3/KCNK3/CYP21A2/ADCY4/TCF7L2/PRKACA/NR4A1/FZD2/GNAS/POMC/FZD1/NR5A1	28
KEGG	hsa04922	Glucagon signaling pathway	21/868	107/8144	0.003985	0.0275	0.01992	CAMK2G/CRTC2/PLCB1/CREB1/LDHB/PLCB3/AKT3/CAMK2A/AKT1/CREB3L2/SLC2A1/PCK2/PLCB4/CREB5/PPP3R2/PRKACA/PFKP/PHKB/LDHAL6B/GNAS/PRKAG3	21
KEGG	hsa04380	Osteoclast differentiation	24/868	128/8144	0.004037	0.0275	0.01992	MITF/CREB1/AKT3/PPARG/FOSL2/MAPK12/CSF1/AKT1/LCK/JAK1/MAP3K14/FYN/SIRPA/PIK3R1/JUNB/MAPK3/TGFBR1/NCF2/PPP3R2/CSF1R/PIK3CB/FOS/PIK3R3/TNFRSF1A	24
KEGG	hsa05110	Vibrio cholerae infection	12/868	50/8144	0.005262	0.03434	0.02487	SEC61G/ADCY9/ACTG1/TCIRG1/ATP6V1C1/PLCG1/PRKACA/SEC61A1/GNAS/ARF1/ATP6V0A1/CFTR	12
KEGG	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	18/868	89/8144	0.005332	0.03434	0.02487	AKT3/CSNK2A1/MAPK12/AKT1/LCK/ALK/NFATC3/JAK1/PIK3R1/MAPK3/BATF2/PLCG1/LAT/PPP3R2/PIK3CB/FOS/EGF/PIK3R3	18
KEGG	hsa04360	Axon guidance	31/868	182/8144	0.005455	0.03434	0.02487	CAMK2G/NCK2/CAMK2A/EPHA6/SRGAP3/SRGAP1/NFATC3/PTK2/ARHGEF12/SEMA3D/PLXNC1/GDF7/NTNG1/FYN/MYL5/EPHA3/PIK3R1/DPYSL5/MAPK3/PLXNB2/ROCK1/SEMA4C/PLCG1/SEMA3G/PPP3R2/PIK3CB/PLXNA2/PIK3R3/DCC/CDC42/PAK3	31
KEGG	hsa05414	Dilated cardiomyopathy	19/868	96/8144	0.00546	0.03434	0.02487	ITGA9/TNNC1/MYL3/ADCY9/ITGA6/ATP2A2/CACNB1/ACTG1/LMNA/ITGA3/ADCY5/CACNA2D1/ITGA7/ADCY4/PRKACA/CACNB2/CACNG7/GNAS/ITGB5	19
KEGG	hsa04660	T cell receptor signaling pathway	20/868	104/8144	0.00619	0.03819	0.02766	NCK2/AKT3/MAPK12/AKT1/LCK/NFATC3/MAP3K14/FYN/PIK3R1/MAPK3/PLCG1/LAT/ITK/PPP3R2/VAV2/PIK3CB/FOS/PIK3R3/CDC42/PAK3	20
KEGG	hsa05165	Human papillomavirus infection	50/868	331/8144	0.006546	0.03964	0.02871	TNXB/WNT3/ITGA9/ITGA6/CREB1/COL4A2/AKT3/CDKN1A/COL4A1/PDGFRB/TCIRG1/AKT1/CREB3L2/ATP6V1C1/SLC9A3R1/JAK1/PTK2/COL9A1/TCF7L1/ITGA3/PTGER4/THBS4/CSNK1A1/COL1A1/CREB5/PIK3R1/VWF/MAPK3/LAMA4/SPP1/RBPJL/COL4A5/LAMA3/ITGA7/PPP2R5C/TCF7L2/LFNG/PRKACA/PIK3CB/TSC2/CHAD/FZD2/EGF/PIK3R3/GNAS/TNFRSF1A/CDC42/ITGB5/ATP6V0A1/FZD1	50
KEGG	hsa04270	Vascular smooth muscle contraction	24/868	134/8144	0.007295	0.04337	0.03141	PLA2G4B/PLA2G12A/ADCY9/PLCB1/PPP1CC/PLCB3/GNA11/RAMP2/AVPR1A/ARHGEF12/PLCB4/PPP1CA/ADCY5/MAPK3/ROCK1/ADORA2A/ADCY4/KCNU1/PRKACA/NPPA/CALCA/PRKCB/EDN2/GNAS	24
KEGG	hsa05222	Small cell lung cancer	18/868	92/8144	0.007616	0.04447	0.03221	TRAF5/RXRA/ITGA6/COL4A2/BIRC7/AKT3/CDKN1A/COL4A1/AKT1/PTK2/ITGA3/PIK3R1/LAMA4/COL4A5/LAMA3/PIK3CB/MYC/PIK3R3	18
KEGG	hsa05223	Non-small cell lung cancer	15/868	72/8144	0.007936	0.04553	0.03298	RXRA/AKT3/CDKN1A/AKT1/ALK/STAT5A/RET/PIK3R1/MAPK3/JAK3/PLCG1/PIK3CB/EGF/PRKCB/PIK3R3	15
KEGG	hsa04810	Regulation of actin cytoskeleton	35/868	218/8144	0.008488	0.04681	0.0339	FGFR3/ITGA9/PPP1CC/SLC9A1/ARPC2/ITGA6/PIP5K1C/ACTG1/PDGFRB/RRAS2/PTK2/ARHGEF7/ACTN1/ARHGEF12/ITGA3/BAIAP2/PPP1CA/MYL5/PIK3R1/MAPK3/ITGB2/ROCK1/ARHGAP35/ITGA7/VAV2/IQGAP2/PIK3CB/EGF/WASF1/PIK3R3/ACTN4/CDC42/WASF2/PAK3/ITGB5	35
KEGG	hsa05017	Spinocerebellar ataxia	25/868	143/8144	0.008536	0.04681	0.0339	PPIF/PSMB7/BEAN1/PLCB1/ATP2A2/GRIN2C/PLCB3/AKT3/AKT1/PLCB4/AMBRA1/PIK3R1/ATXN2/KCNC3/RBPJL/ATXN1/ATXN3/PIK3CB/ERN1/OMA1/PRKCB/GRIN3B/PIK3R3/GRIA1/WIPI2	25
KEGG	hsa04961	Endocrine and other factor-regulated calcium reabsorption	12/868	53/8144	0.008589	0.04681	0.0339	ADCY9/PLCB1/PLCB3/PLCB4/AP2A2/KLK2/PRKACA/VDR/PRKCB/GNAS/CLTC/FXYD2	12
KEGG	hsa04210	Apoptosis	24/868	136/8144	0.008772	0.04702	0.03406	AKT3/ACTG1/CAPN2/LMNA/AKT1/RIPK1/CASP7/MAP3K14/BID/CTSC/PIK3R1/CTSW/MAPK3/TNFSF10/MCL1/PARP3/PIK3CB/FOS/ERN1/PTPN13/PIK3R3/TNFRSF1A/CTSH/TUBA1C	24
KEGG	hsa04720	Long-term potentiation	14/868	67/8144	0.009873	0.05063	0.03667	CAMK2G/PLCB1/PPP1CC/GRIN2C/PLCB3/CAMK2A/PLCB4/PPP1CA/MAPK3/PPP3R2/RAPGEF3/PRKACA/PRKCB/GRIA1	14
KEGG	hsa05221	Acute myeloid leukemia	14/868	67/8144	0.009873	0.05063	0.03667	AKT3/AKT1/STAT5A/TCF7L1/PIK3R1/MAPK3/TCF7L2/RUNX1T1/CSF1R/PIK3CB/MYC/PIM1/PIK3R3/FLT3	14
KEGG	hsa04310	Wnt signaling pathway	28/868	167/8144	0.009909	0.05063	0.03667	CAMK2G/NOTUM/WNT3/TLE6/PLCB1/PLCB3/CSNK2A1/CAMK2A/NFATC3/VANGL1/TCF7L1/PLCB4/CSNK1A1/DKK4/DAAM2/PPP3R2/SIAH1/SKP1/TCF7L2/PRKACA/SOST/FZD2/LRP5/MYC/PRKCB/CTBP1/DKK2/FZD1	28
KEGG	hsa04972	Pancreatic secretion	19/868	102/8144	0.01058	0.05255	0.03806	PLA2G12A/ADCY9/PLCB1/SLC9A1/ATP2A2/CTRB1/PLCB3/CPB1/PLCB4/ADCY5/CLCA4/ADCY4/CELA2A/SCT/PRKCB/GNAS/FXYD2/CTRL/CFTR	19
KEGG	hsa04540	Gap junction	17/868	88/8144	0.01061	0.05255	0.03806	ADCY9/PLCB1/MAP2K5/PLCB3/GNA11/PDGFRB/TUBB2A/PLCB4/ADCY5/MAPK3/ADCY4/PRKACA/EGF/PRKCB/GNAS/GJA1/TUBA1C	17
KEGG	hsa04211	Longevity regulating pathway	17/868	89/8144	0.01185	0.05755	0.04169	ADCY9/ADIPOQ/CREB1/AKT3/PPARG/AKT1/CREB3L2/CREB5/ADCY5/PIK3R1/ATG5/ADCY4/PRKACA/PIK3CB/TSC2/PIK3R3/PRKAG3	17
KEGG	hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	5/868	14/8144	0.01197	0.05755	0.04169	CHST2/ST3GAL3/CHST1/B4GALT2/CHST4	5
KEGG	hsa04971	Gastric acid secretion	15/868	76/8144	0.01306	0.06129	0.0444	CAMK2G/ADCY9/PLCB1/SLC9A1/PLCB3/ACTG1/CAMK2A/PLCB4/ADCY5/HRH2/ADCY4/PRKACA/PRKCB/GNAS/CFTR	15
KEGG	hsa04070	Phosphatidylinositol signaling system	18/868	97/8144	0.01312	0.06129	0.0444	PLCB1/IP6K3/PIP5K1C/PLCB3/CDS1/DGKZ/PLCB4/PIK3R1/DGKE/ITPKA/PLCG1/INPP4B/SACM1L/PIK3CB/CDIPT/PRKCB/PIK3R3/INPP5A	18
KEGG	hsa04960	Aldosterone-regulated sodium reabsorption	9/868	37/8144	0.01357	0.06165	0.04465	PIK3R1/MAPK3/SLC9A3R2/SGK1/PIK3CB/PRKCB/PIK3R3/SCNN1A/FXYD2	9
KEGG	hsa05143	African trypanosomiasis	9/868	37/8144	0.01357	0.06165	0.04465	PLCB1/APOL1/PLCB3/HBA2/PLCB4/LAMA4/IL12B/NPPA/PRKCB	9
KEGG	hsa04668	TNF signaling pathway	20/868	112/8144	0.01399	0.06269	0.0454	MMP14/TRAF5/CREB1/AKT3/MAPK12/CSF1/AKT1/CREB3L2/RIPK1/CASP7/MAP3K14/CREB5/PIK3R1/JUNB/MAPK3/TAB3/PIK3CB/FOS/PIK3R3/TNFRSF1A	20
KEGG	hsa04917	Prolactin signaling pathway	14/868	70/8144	0.01445	0.06316	0.04574	AKT3/MAPK12/AKT1/STAT5A/PRL/PIK3R1/MAPK3/TH/CSN2/PIK3CB/ELF5/FOS/PIK3R3/SOCS2	14
KEGG	hsa05100	Bacterial invasion of epithelial cells	15/868	77/8144	0.01468	0.06316	0.04574	CAV1/ARPC2/ACTG1/PTK2/CAV3/PIK3R1/CBL/ELMO3/CD2AP/PIK3CB/WASF1/PIK3R3/CLTC/CDC42/WASF2	15
KEGG	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	15/868	77/8144	0.01468	0.06316	0.04574	ITGA9/ITGA6/ATP2A2/CACNB1/ACTG1/LMNA/TCF7L1/ITGA3/CACNA2D1/ITGA7/TCF7L2/CACNB2/CACNG7/GJA1/ITGB5	15
KEGG	hsa05130	Pathogenic Escherichia coli infection	31/868	197/8144	0.01671	0.07056	0.05111	NCK2/MYO1D/ARPC2/CLDN16/CLDN15/PYCARD/WIPF3/ACTG1/MAPK12/MYO1B/RIPK1/SLC9A3R1/ARHGEF12/CASP7/TUBB2A/BAIAP2/MYO1G/FYN/MAPK3/ROCK1/TAB3/TNFSF10/FOS/WIPF2/WASF1/TNFRSF1A/CDC42/WASF2/ARF1/PAK3/TUBA1C	31
KEGG	hsa04724	Glutamatergic synapse	20/868	114/8144	0.01683	0.07056	0.05111	PLA2G4B/ADCY9/PLCB1/GRIN2C/GNG4/PLCB3/GNB2/GNB4/GNG10/PLCB4/ADCY5/MAPK3/PPP3R2/GRM8/ADCY4/PRKACA/PRKCB/GRIN3B/GNAS/GRIA1	20
KEGG	hsa05210	Colorectal cancer	16/868	86/8144	0.01826	0.07524	0.0545	MSH6/AKT3/CDKN1A/AKT1/TCF7L1/PIK3R1/MAPK3/TGFBR1/TCF7L2/PIK3CB/FOS/MYC/EGF/SMAD2/PIK3R3/DCC	16
KEGG	hsa04726	Serotonergic synapse	20/868	115/8144	0.01841	0.07524	0.0545	PLA2G4B/PLCB1/ALOX15B/GNG4/PLCB3/TPH2/GNB2/GNB4/KCNJ9/GNG10/PLCB4/ADCY5/MAPK3/HTR1D/RAPGEF3/PRKACA/PRKCB/GNAS/MAOA/ALOX12B	20
KEGG	hsa05225	Hepatocellular carcinoma	27/868	168/8144	0.01897	0.07658	0.05546	WNT3/HMOX1/AKT3/SMARCD1/CDKN1A/ACTG1/AKT1/SMARCD2/TCF7L1/CSNK1A1/PIK3R1/ACTL6B/MAPK3/TGFBR1/PLCG1/MGST2/TCF7L2/GSTT2/PIK3CB/FZD2/LRP5/MYC/PHF10/PRKCB/SMAD2/PIK3R3/FZD1	27
KEGG	hsa00010	Glycolysis / Gluconeogenesis	13/868	67/8144	0.02289	0.09129	0.06612	ALDH3B1/ALDH7A1/LDHB/PGK1/ACSS1/PCK2/GAPDHS/ALDH3A1/PFKP/LDHAL6B/ADH7/ACSS2/ADH1B	13
KEGG	hsa00620	Pyruvate metabolism	10/868	47/8144	0.024	0.09454	0.06847	ALDH7A1/LDHB/LDHD/ACSS1/PCK2/ACOT12/LDHAL6B/ADH7/ACSS2/ADH1B	10
KEGG	hsa05214	Glioma	14/868	75/8144	0.02551	0.09932	0.07193	CAMK2G/AKT3/CDKN1A/PDGFRB/CAMK2A/AKT1/PIK3R1/MAPK3/PLCG1/CAMK1/PIK3CB/EGF/PRKCB/PIK3R3	14
KEGG	hsa05207	Chemical carcinogenesis - receptor activation	32/868	212/8144	0.02636	0.1014	0.07345	ADCY9/MIRLET7A3/RXRA/CREB1/AKT3/PAQR7/DLL4/AKT1/CREB3L2/STAT5A/NR1I3/CREB5/ADCY5/PIK3R1/MAPK3/ARRB2/MIRLET7B/ADCY4/MGST2/GSTT2/PRKACA/ARRB1/PIK3CB/FOS/VDR/PAQR5/MYC/EGF/PRKCB/PIK3R3/GNAS/MIRLET7D	32
KEGG	hsa04152	AMPK signaling pathway	20/868	120/8144	0.02808	0.1068	0.07733	CRTC2/ADIPOQ/CREB1/AKT3/PPARG/AKT1/CREB3L2/CAB39/PCK2/CREB5/PIK3R1/LIPE/PPP2R5C/LEP/PIK3CB/TSC2/PFKP/PIK3R3/PRKAG3/CFTR	20
KEGG	hsa05211	Renal cell carcinoma	13/868	69/8144	0.02863	0.1075	0.07782	AKT3/CDKN1A/AKT1/SLC2A1/PIK3R1/MAPK3/CUL2/RAPGEF1/PIK3CB/EGLN2/PIK3R3/CDC42/PAK3	13
KEGG	hsa01522	Endocrine resistance	17/868	98/8144	0.02892	0.1075	0.07782	ADCY9/HBEGF/AKT3/CDKN1A/MAPK12/DLL4/AKT1/PTK2/ADCY5/PIK3R1/MAPK3/ADCY4/PRKACA/PIK3CB/FOS/PIK3R3/GNAS	17
KEGG	hsa05032	Morphine addiction	16/868	91/8144	0.02983	0.1096	0.07939	ADCY9/GNG4/GNB2/PDE8A/GNB4/GRK5/KCNJ9/GNG10/GABRR3/ADCY5/ARRB2/ADCY4/PRKACA/ARRB1/PRKCB/GNAS	16
KEGG	hsa04022	cGMP-PKG signaling pathway	26/868	167/8144	0.0302	0.1097	0.07946	PPIF/ADCY9/PLCB1/PPP1CC/ATP2A2/CREB1/PLCB3/AKT3/GNA11/MEF2D/AKT1/CREB3L2/NFATC3/PLCB4/PIK3CG/PPP1CA/CREB5/ADCY5/MAPK3/ROCK1/PPP3R2/PDE5A/ADCY4/KCNU1/NPPA/FXYD2	26
KEGG	hsa05030	Cocaine addiction	10/868	49/8144	0.0314	0.1128	0.08171	GRIN2C/CREB1/CREB3L2/CREB5/ADCY5/TH/PRKACA/GRIN3B/GNAS/MAOA	10
KEGG	hsa04340	Hedgehog signaling pathway	11/868	56/8144	0.032	0.1137	0.08236	DISP1/CSNK1G2/SPOPL/CSNK1A1/SMURF1/ARRB2/SPOP/PRKACA/ARRB1/KIF3A/IQCE	11
KEGG	hsa00350	Tyrosine metabolism	8/868	36/8144	0.03264	0.1137	0.08236	ALDH3B1/COMT/HPD/TH/ALDH3A1/MAOA/ADH7/ADH1B	8
KEGG	hsa04658	Th1 and Th2 cell differentiation	16/868	92/8144	0.03269	0.1137	0.08236	HLA-DOB/IL12RB2/MAPK12/DLL4/LCK/NFATC3/JAK1/STAT5A/MAPK3/JAK3/RBPJL/PLCG1/LAT/PPP3R2/IL12B/FOS	16
KEGG	hsa04915	Estrogen signaling pathway	22/868	138/8144	0.03465	0.1193	0.08637	ADCY9/HBEGF/PLCB1/CREB1/PLCB3/AKT3/AKT1/CREB3L2/KCNJ9/PLCB4/CREB5/ADCY5/PIK3R1/MAPK3/KRT17/ADCY4/PRKACA/PIK3CB/FOS/PIK3R3/GNAS/POMC	22
KEGG	hsa04931	Insulin resistance	18/868	108/8144	0.03592	0.1224	0.08862	CRTC2/PPP1CC/CREB1/AKT3/AKT1/CREB3L2/PTPRF/SLC2A1/PCK2/PPP1CA/CREB5/PIK3R1/GFPT2/PIK3CB/PRKCB/PIK3R3/PRKAG3/TNFRSF1A	18
KEGG	hsa05418	Fluid shear stress and atherosclerosis	22/868	139/8144	0.03719	0.1254	0.09081	CAV1/MAP2K5/HMOX1/SUMO2/AKT3/ACTG1/MAPK12/AKT1/PTK2/ASS1/KLF2/CAV3/PIK3R1/PECAM1/NCF2/MGST2/GSTT2/PIK3CB/FOS/PIK3R3/PIAS4/TNFRSF1A	22
KEGG	hsa05216	Thyroid cancer	8/868	37/8144	0.0379	0.1264	0.09158	RXRA/PPARG/CDKN1A/TCF7L1/RET/MAPK3/TCF7L2/MYC	8
KEGG	hsa05213	Endometrial cancer	11/868	58/8144	0.0403	0.133	0.09634	AKT3/CDKN1A/AKT1/TCF7L1/PIK3R1/MAPK3/TCF7L2/PIK3CB/MYC/EGF/PIK3R3	11
KEGG	hsa05142	Chagas disease	17/868	102/8144	0.04068	0.133	0.09634	PLCB1/PLCB3/AKT3/GNA11/MAPK12/AKT1/PLCB4/PIK3R1/MAPK3/TGFBR1/IL12B/PIK3CB/FOS/SMAD2/PIK3R3/GNAS/TNFRSF1A	17
KEGG	hsa04722	Neurotrophin signaling pathway	19/868	119/8144	0.04658	0.1508	0.1092	CAMK2G/SORT1/MAP2K5/AKT3/CAMK2A/YWHAE/MAPK12/AKT1/SH2B2/PIK3R1/MAPK3/PLCG1/RAPGEF1/PIK3CB/NTRK3/MAP3K1/PIK3R3/CDC42/NTF3	19
KEGG	hsa04625	C-type lectin receptor signaling pathway	17/868	104/8144	0.0477	0.1529	0.1108	IL17D/AKT3/PYCARD/MAPK12/RRAS2/AKT1/NFATC3/ARHGEF12/MAP3K14/PIK3R1/MAPK3/PPP3R2/IL12B/LSP1/PIK3CB/PIK3R3/EGR2	17
KEGG	hsa04014	Ras signaling pathway	33/868	232/8144	0.05085	0.1614	0.1169	PLA2G4B/FGFR3/PLA2G12A/RASA3/GNG4/RASGRP3/AKT3/GNB2/PDGFRB/SYNGAP1/CSF1/RRAS2/AKT1/GNB4/GNG10/ANGPT1/PIK3R1/MAPK3/PGF/RASAL2/PLCG1/LAT/CSF1R/PRKACA/PIK3CB/EGF/PRKCB/RASAL3/PIK3R3/FLT3/CDC42/PAK3/NTF3	33
KEGG	hsa04918	Thyroid hormone synthesis	13/868	75/8144	0.05204	0.1617	0.1171	ADCY9/PLCB1/CREB1/PLCB3/CREB3L2/PLCB4/CREB5/ADCY5/ADCY4/PRKACA/PRKCB/GNAS/FXYD2	13
KEGG	hsa05410	Hypertrophic cardiomyopathy	15/868	90/8144	0.05232	0.1617	0.1171	ITGA9/TNNC1/MYL3/ITGA6/ATP2A2/CACNB1/ACTG1/LMNA/ITGA3/CACNA2D1/ITGA7/CACNB2/CACNG7/PRKAG3/ITGB5	15
KEGG	hsa05132	Salmonella infection	35/868	249/8144	0.05241	0.1617	0.1171	RHOJ/ARPC2/FLNB/AKT3/PYCARD/SNX33/VPS18/ACTG1/NOD1/MAPK12/AKT1/RIPK1/TCF7L1/CASP7/TUBB2A/PIK3CG/MYL5/MAPK3/TAB3/TNFSF10/SKP1/TCF7L2/PIK3CB/EXOC4/FOS/MYC/PLEKHM1/DYNLT1/AHNAK/DCTN2/TNFRSF1A/CDC42/ARF1/PAK3/TUBA1C	35
KEGG	hsa04664	Fc epsilon RI signaling pathway	12/868	68/8144	0.05383	0.1645	0.1191	PLA2G4B/AKT3/MAPK12/AKT1/FYN/PIK3R1/MAPK3/PLCG1/LAT/VAV2/PIK3CB/PIK3R3	12
KEGG	hsa04910	Insulin signaling pathway	21/868	137/8144	0.05505	0.1667	0.1207	PPP1CC/AKT3/RHOQ/AKT1/SH2B2/PTPRF/PCK2/PPP1CA/PIK3R1/LIPE/CBL/MAPK3/RAPGEF1/PRKACA/PIK3CB/TSC2/PHKB/PIK3R3/PRKAG3/SOCS2/INPP5A	21
KEGG	hsa05220	Chronic myeloid leukemia	13/868	76/8144	0.05694	0.1708	0.1237	AKT3/CDKN1A/BCR/AKT1/STAT5A/PIK3R1/CBL/MAPK3/TGFBR1/PIK3CB/MYC/PIK3R3/CTBP1	13
KEGG	hsa04924	Renin secretion	12/868	69/8144	0.05913	0.1758	0.1273	PLCB1/CREB1/PLCB3/PTGER4/PLCB4/ADCY5/CLCA4/PPP3R2/PRKACA/NPPA/EDN2/GNAS	12
KEGG	hsa04213	Longevity regulating pathway - multiple species	11/868	62/8144	0.06115	0.1797	0.1301	ADCY9/AKT3/AKT1/ADCY5/PIK3R1/ATG5/ADCY4/PRKACA/PIK3CB/PIK3R3/PRKAG3	11
KEGG	hsa04010	MAPK signaling pathway	40/868	294/8144	0.06154	0.1797	0.1301	PLA2G4B/FGFR3/DUSP8/MAP2K5/FLNB/RASGRP3/CACNB1/AKT3/PDGFRB/MAPK12/CSF1/RRAS2/AKT1/NFATC3/MAP3K6/MAP3K14/ANGPT1/MAPKAPK3/ELK4/MAPK3/ARRB2/CACNA2D1/PGF/TGFBR1/PPP3R2/CSF1R/PRKACA/ARRB1/FOS/MAP3K1/NR4A1/CACNB2/MYC/EGF/PRKCB/CACNG7/FLT3/TNFRSF1A/CDC42/NTF3	40
KEGG	hsa04216	Ferroptosis	8/868	41/8144	0.06447	0.1865	0.1351	GPX4/HMOX1/MAP1LC3B2/STEAP3/PCBP1/ATG5/ACSL1/FTH1	8
KEGG	hsa04142	Lysosome	20/868	132/8144	0.06628	0.1888	0.1367	SORT1/TCIRG1/AP1G1/NPC2/DMXL2/CTSC/NCOA7/CTSW/MAN2B1/AP3D1/LAMP1/SGSH/AP1S1/DNASE2/LGMN/IGF2R/PPT1/CLTC/CTSH/ATP6V0A1	20
KEGG	hsa04970	Salivary secretion	15/868	93/8144	0.06639	0.1888	0.1367	ADCY9/PLCB1/SLC9A1/PLCB3/CST4/PLCB4/CAMP/ADCY5/ADCY4/CST2/PRKACA/RYR3/PRKCB/GNAS/FXYD2	15
KEGG	hsa00730	Thiamine metabolism	4/868	15/8144	0.06731	0.1898	0.1374	AK1/AK4/AK2/TPK1	4
KEGG	hsa05131	Shigellosis	34/868	247/8144	0.07016	0.1961	0.142	TRAF5/PLCB1/MAP1LC3B2/ARPC2/PLCB3/AKT3/PYCARD/ACTG1/CAPN2/NOD1/MAPK12/AKT1/RIPK1/PTK2/ACTN1/RRAGA/PLCB4/MYL5/PIK3R1/MAPK3/ROCK1/PLCG1/TAB3/ATG5/SKP1/PIK3CB/WASF1/PIK3R3/ACTN4/TNFRSF1A/CDC42/WASF2/WIPI2/ARF1	34
KEGG	hsa04613	Neutrophil extracellular trap formation	27/868	190/8144	0.07261	0.2012	0.1457	PPIF/AGER/HDAC5/PLCB1/PLCB3/SELPLG/AKT3/ACTG1/MAPK12/AKT1/ELANE/TLR8/PLCB4/CAMP/PIK3R1/HDAC3/VWF/MAPK3/ITGB2/PLCG1/NCF2/PADI4/PIK3CB/PRKCB/PIK3R3/CLCN5/FPR1	27
KEGG	hsa05417	Lipid and atherosclerosis	30/868	215/8144	0.0739	0.2031	0.1471	CAMK2G/AGER/PLCB1/RXRA/PLCB3/AKT3/PYCARD/PPARG/CAMK2A/MAPK12/AKT1/NFATC3/PTK2/CASP7/PLCB4/BID/PIK3R1/MAPK3/PLCG1/NCF2/PPP3R2/TNFSF10/VAV2/IL12B/PIK3CB/FOS/ERN1/PIK3R3/TNFRSF1A/CDC42	30
KEGG	hsa00340	Histidine metabolism	5/868	22/8144	0.07732	0.2107	0.1526	ALDH3B1/ALDH7A1/ALDH3A1/CARNS1/MAOA	5
KEGG	hsa04974	Protein digestion and absorption	16/868	103/8144	0.07819	0.2113	0.153	COL4A2/CTRB1/COL13A1/COL4A1/CPB1/COL9A1/COL7A1/COL1A1/COL15A1/COL5A2/COL4A5/CELA2A/DPP4/COL14A1/FXYD2/CTRL	16
KEGG	hsa04071	Sphingolipid signaling pathway	18/868	119/8144	0.07945	0.2116	0.1533	PLCB1/PLCB3/AKT3/MAPK12/AKT1/SMPD2/PLCB4/FYN/BID/PIK3R1/MAPK3/ROCK1/PPP2R5C/PIK3CB/SGPP1/PRKCB/PIK3R3/TNFRSF1A	18
KEGG	hsa04550	Signaling pathways regulating pluripotency of stem cells	21/868	143/8144	0.07959	0.2116	0.1533	DLX5/WNT3/FGFR3/AKT3/MAPK12/AKT1/JAK1/SKIL/PIK3R1/MAPK3/JAK3/POU5F1/PAX6/NANOG/PIK3CB/FZD2/MYC/SMAD2/PIK3R3/MYF5/FZD1	21
KEGG	hsa00360	Phenylalanine metabolism	4/868	16/8144	0.08248	0.2175	0.1575	ALDH3B1/HPD/ALDH3A1/MAOA	4
KEGG	hsa00562	Inositol phosphate metabolism	12/868	73/8144	0.08377	0.2191	0.1587	PLCB1/PIP5K1C/PLCB3/PLCB4/PIK3CG/ITPKA/PLCG1/INPP4B/SACM1L/PIK3CB/CDIPT/INPP5A	12
KEGG	hsa00330	Arginine and proline metabolism	9/868	51/8144	0.08761	0.2234	0.1618	ALDH7A1/PYCR2/ODC1/P4HA1/CKB/AGMAT/SRM/CARNS1/MAOA	9
KEGG	hsa04913	Ovarian steroidogenesis	9/868	51/8144	0.08761	0.2234	0.1618	PLA2G4B/ADCY9/CYP11A1/ADCY5/ADCY4/PRKACA/CYP19A1/GNAS/AKR1C3	9
KEGG	hsa04976	Bile secretion	14/868	89/8144	0.08766	0.2234	0.1618	ADCY9/RXRA/SLC9A1/SLC2A1/SLC22A1/ADCY5/SLC4A5/SLCO1B3/ADCY4/PRKACA/SCT/GNAS/FXYD2/CFTR	14
KEGG	hsa05167	Kaposi sarcoma-associated herpesvirus infection	27/868	194/8144	0.08855	0.2234	0.1618	MAP1LC3B2/CREB1/GNG4/AKT3/CDKN1A/GNB2/MAPK12/AKT1/NFATC3/JAK1/GNB4/TCF7L1/GNG10/PIK3CG/BID/CCR3/PIK3R1/MAPK3/PLCG1/PPP3R2/TCF7L2/PIK3CB/FOS/CLEC2B/MYC/PIK3R3/TNFRSF1A	27
KEGG	hsa05215	Prostate cancer	15/868	97/8144	0.08879	0.2234	0.1618	CREB1/AKT3/CDKN1A/PDGFRB/AKT1/CREB3L2/TCF7L1/CREB5/PIK3R1/MAPK3/TCF7L2/PIK3CB/EGF/PIK3R3/NKX3-1	15
KEGG	hsa00515	Mannose type O-glycan biosynthesis	5/868	23/8144	0.09053	0.226	0.1637	POMGNT1/ST3GAL3/MGAT5B/B4GALT2/CHST10	5
KEGG	hsa04330	Notch signaling pathway	10/868	59/8144	0.09231	0.2278	0.165	NCOR2/TLE6/DLL4/RBPJL/ATXN1/APH1A/LFNG/NUMBL/CTBP1/CIR1	10
KEGG	hsa05161	Hepatitis B	23/868	162/8144	0.09265	0.2278	0.165	CREB1/AKT3/CDKN1A/MAPK12/AKT1/CREB3L2/NFATC3/JAK1/STAT5A/BID/CREB5/PIK3R1/MAPK3/JAK3/TGFBR1/PIK3CB/FOS/MAP3K1/HSPG2/MYC/PRKCB/PIK3R3/EGR2	23
KEGG	hsa00120	Primary bile acid biosynthesis	4/868	17/8144	0.09916	0.2402	0.174	CYP46A1/HSD3B7/AMACR/ACOX2	4
KEGG	hsa00910	Nitrogen metabolism	4/868	17/8144	0.09916	0.2402	0.174	CA7/CA6/CA12/GLUD2	4
KEGG	hsa05212	Pancreatic cancer	12/868	76/8144	0.1059	0.2547	0.1844	AKT3/CDKN1A/AKT1/JAK1/PIK3R1/MAPK3/TGFBR1/PIK3CB/EGF/SMAD2/PIK3R3/CDC42	12
KEGG	hsa04659	Th17 cell differentiation	16/868	108/8144	0.1084	0.2587	0.1874	RXRA/HLA-DOB/MAPK12/LCK/NFATC3/JAK1/STAT5A/MAPK3/JAK3/IL27RA/TGFBR1/PLCG1/LAT/PPP3R2/FOS/SMAD2	16
KEGG	hsa04140	Autophagy - animal	20/868	141/8144	0.1118	0.2642	0.1913	MAP1LC3B2/AKT3/DAPK2/RRAS2/AKT1/ATG9B/RRAGA/AMBRA1/ATG4B/RAB33B/PIK3R1/MAPK3/LAMP1/ATG5/PRKACA/PIK3CB/ERN1/TSC2/PIK3R3/WIPI2	20
KEGG	hsa04920	Adipocytokine signaling pathway	11/868	69/8144	0.1123	0.2642	0.1913	ADIPOQ/RXRA/AKT3/AKT1/SLC2A1/PCK2/LEP/ACSL1/POMC/PRKAG3/TNFRSF1A	11
KEGG	hsa00640	Propanoate metabolism	6/868	32/8144	0.1187	0.2772	0.2008	LDHB/ABAT/ACSS1/PCCA/LDHAL6B/ACSS2	6
KEGG	hsa04742	Taste transduction	13/868	86/8144	0.123	0.2853	0.2067	PLCB1/PLCB3/TAS2R9/PLCB4/TAS1R3/HTR1D/TAS2R19/SCN9A/ADCY4/PRKACA/P2RX3/TAS2R1/SCNN1A	13
KEGG	hsa00310	Lysine degradation	10/868	63/8144	0.1288	0.2965	0.2148	ALDH7A1/CAMKMT/PRDM16/SETMAR/DOT1L/SMYD2/SETD7/SUV39H2/PRDM7/SETD1A	10
KEGG	hsa01521	EGFR tyrosine kinase inhibitor resistance	12/868	79/8144	0.1312	0.2983	0.2161	FGFR3/AKT3/PDGFRB/AKT1/JAK1/PIK3R1/MAPK3/PLCG1/PIK3CB/EGF/PRKCB/PIK3R3	12
KEGG	hsa04260	Cardiac muscle contraction	13/868	87/8144	0.1314	0.2983	0.2161	TNNC1/MYL3/SLC9A1/COX4I2/ATP2A2/CACNB1/UQCRH/CACNA2D1/ASPH/TRDN/CACNB2/CACNG7/FXYD2	13
KEGG	hsa05170	Human immunodeficiency virus 1 infection	28/868	212/8144	0.1353	0.3051	0.221	TRAF5/GNG4/AKT3/GNA11/CUL5/GNB2/MAPK12/AKT1/RIPK1/NFATC3/PTK2/GNB4/AP1G1/GNG10/BID/PIK3R1/MAPK3/AP1S1/PLCG1/PPP3R2/SKP1/PIK3CB/FOS/APOBEC3D/PRKCB/PIK3R3/TNFRSF1A/PAK3	28
KEGG	hsa05219	Bladder cancer	7/868	41/8144	0.1405	0.3148	0.228	FGFR3/HBEGF/CDKN1A/DAPK2/MAPK3/MYC/EGF	7
KEGG	hsa05152	Tuberculosis	24/868	180/8144	0.1463	0.3255	0.2357	CAMK2G/MRC2/CREB1/HLA-DOB/AKT3/CAMK2A/MAPK12/TCIRG1/AKT1/JAK1/ARHGEF12/BID/CAMP/MAPK3/ITGB2/LAMP1/PPP3R2/IL12B/LSP1/VDR/CD74/TNFRSF1A/ATP6V0A1/TLR1	24
KEGG	hsa03020	RNA polymerase	6/868	34/8144	0.1476	0.3261	0.2362	POLR1E/POLR2J2/POLR3E/CRCP/POLR2D/POLR2C	6
KEGG	hsa04727	GABAergic synapse	13/868	89/8144	0.149	0.3269	0.2368	ADCY9/TRAK2/GNG4/GNB2/ABAT/GNB4/GNG10/GABRR3/ADCY5/ADCY4/PLCL1/PRKACA/PRKCB	13
KEGG	hsa01524	Platinum drug resistance	11/868	73/8144	0.15	0.3269	0.2368	MSH6/AKT3/CDKN1A/AKT1/BID/PIK3R1/MAPK3/MGST2/GSTT2/PIK3CB/PIK3R3	11
KEGG	hsa04068	FoxO signaling pathway	18/868	131/8144	0.156	0.3378	0.2446	AKT3/CDKN1A/MAPK12/AKT1/C8orf44-SGK3/PCK2/KLF2/PIK3R1/MAPK3/FBXO32/SETD7/TGFBR1/SGK1/TNFSF10/PIK3CB/EGF/PIK3R3/PRKAG3	18
KEGG	hsa04662	B cell receptor signaling pathway	12/868	82/8144	0.1595	0.3431	0.2485	RASGRP3/AKT3/AKT1/NFATC3/PIK3R1/MAPK3/PPP3R2/VAV2/PIK3CB/FOS/PRKCB/PIK3R3	12
KEGG	hsa04120	Ubiquitin mediated proteolysis	19/868	142/8144	0.1763	0.3767	0.2729	RHOBTB2/BIRC7/CUL5/UBE2E2/HERC2/UBE2L6/FZR1/SMURF1/CBL/UBE4A/UBE2R2/CUL2/SIAH1/UBE2E1/SKP1/MAP3K1/UBE2U/UBR5/PIAS4	19
KEGG	hsa04962	Vasopressin-regulated water reabsorption	7/868	44/8144	0.183	0.3877	0.2808	ADCY9/CREB1/CREB3L2/CREB5/PRKACA/GNAS/DCTN2	7
KEGG	hsa04730	Long-term depression	9/868	60/8144	0.1845	0.3877	0.2808	PLA2G4B/PLCB1/PLCB3/GNA11/PLCB4/MAPK3/PRKCB/GNAS/GRIA1	9
KEGG	hsa05415	Diabetic cardiomyopathy	26/868	203/8144	0.1849	0.3877	0.2808	PPIF/CAMK2G/AGER/PLCB1/PPP1CC/COX4I2/ATP2A2/PLCB3/AKT3/CAMK2A/MAPK12/AKT1/SLC2A1/PDK2/PLCB4/COL1A1/PPP1CA/PIK3R1/UQCRH/GFPT2/TGFBR1/NCF2/PIK3CB/PRKCB/SMAD2/PIK3R3	26
KEGG	hsa05203	Viral carcinogenesis	26/868	204/8144	0.1918	0.3995	0.2893	TRAF5/HDAC5/CREB1/CDKN1A/YWHAE/CREB3L2/JAK1/STAT5A/ACTN1/MRPS18B/CCR3/CREB5/PIK3R1/HDAC3/MAPK3/JAK3/RBPJL/MAD1L1/GTF2H2C/PRKACA/PIK3CB/PIK3R3/ACTN4/CDC42/GTF2E1/EGR2	26
KEGG	hsa00604	Glycosphingolipid biosynthesis - ganglio series	3/868	15/8144	0.2098	0.4343	0.3145	ST6GALNAC4/ST6GALNAC6/SLC33A1	3
KEGG	hsa04930	Type II diabetes mellitus	7/868	46/8144	0.214	0.4391	0.3181	ADIPOQ/MAFA/PIK3R1/MAPK3/PIK3CB/PIK3R3/SOCS2	7
KEGG	hsa04620	Toll-like receptor signaling pathway	14/868	104/8144	0.2149	0.4391	0.3181	AKT3/MAPK12/AKT1/RIPK1/TLR8/PIK3R1/MAPK3/SPP1/TOLLIP/IL12B/PIK3CB/FOS/PIK3R3/TLR1	14
KEGG	hsa04150	mTOR signaling pathway	20/868	156/8144	0.2214	0.4497	0.3257	WNT3/AKT3/AKT1/ATP6V1C1/RRAGA/CAB39/PIK3R1/MAPK3/SGK1/FNIP2/PIK3CB/TSC2/FZD2/PRR5L/LRP5/PRKCB/PIK3R3/TNFRSF1A/TTI1/FZD1	20
KEGG	hsa04614	Renin-angiotensin system	4/868	23/8144	0.2249	0.4539	0.3288	ANPEP/NLN/LNPEP/KLK2	4
KEGG	hsa05160	Hepatitis C	20/868	157/8144	0.2301	0.4591	0.3326	IFIT1B/RXRA/CLDN16/CLDN15/AKT3/CDKN1A/YWHAE/AKT1/RIPK1/JAK1/BID/PIK3R1/MAPK3/PIK3CB/MYC/EGF/RNASEL/PIK3R3/EIF2AK1/TNFRSF1A	20
KEGG	hsa00410	beta-Alanine metabolism	5/868	31/8144	0.2303	0.4591	0.3326	ALDH3B1/ALDH7A1/ABAT/ALDH3A1/CARNS1	5
KEGG	hsa05218	Melanoma	10/868	72/8144	0.2339	0.4635	0.3357	MITF/AKT3/CDKN1A/PDGFRB/AKT1/PIK3R1/MAPK3/PIK3CB/EGF/PIK3R3	10
KEGG	hsa05226	Gastric cancer	19/868	149/8144	0.236	0.4649	0.3367	WNT3/RXRA/AKT3/CDKN1A/AKT1/TCF7L1/CSNK1A1/PIK3R1/MAPK3/TGFBR1/TCF7L2/PIK3CB/FZD2/LRP5/MYC/EGF/SMAD2/PIK3R3/FZD1	19
KEGG	hsa04977	Vitamin digestion and absorption	4/868	24/8144	0.2489	0.4859	0.3519	MMACHC/LMBRD1/SLC19A3/CUBN	4
KEGG	hsa00260	Glycine, serine and threonine metabolism	6/868	40/8144	0.2496	0.4859	0.3519	ALDH7A1/DMGDH/CBS/BHMT/MAOA/SRR	6
KEGG	hsa04061	Viral protein interaction with cytokine and cytokine receptor	13/868	100/8144	0.2653	0.5133	0.3717	CCL26/CSF1/TNFSF14/IL24/CCR3/IL22RA1/TNFSF10/TNFRSF10C/CXCL14/CSF1R/CXCR3/TNFRSF1A/IL19	13
KEGG	hsa03320	PPAR signaling pathway	10/868	75/8144	0.2746	0.5281	0.3825	ADIPOQ/RXRA/PPARG/APOA5/PCK2/PLIN1/APOC3/ACSL1/ACOX2/AQP7	10
KEGG	hsa00510	N-Glycan biosynthesis	7/868	50/8144	0.2808	0.5338	0.3866	MGAT3/MAN1A1/MGAT4B/DPM3/MGAT5B/B4GALT2/ALG6	7
KEGG	hsa04979	Cholesterol metabolism	7/868	50/8144	0.2808	0.5338	0.3866	SORT1/LIPG/NPC2/LCAT/OSBPL5/APOC1/APOC3	7
KEGG	hsa04914	Progesterone-mediated oocyte maturation	13/868	102/8144	0.2892	0.5467	0.396	ADCY9/AKT3/MAPK12/AKT1/ADCY5/FZR1/PIK3R1/MAPK3/MAD1L1/ADCY4/PRKACA/PIK3CB/PIK3R3	13
KEGG	hsa04932	Non-alcoholic fatty liver disease	19/868	155/8144	0.2931	0.5489	0.3976	ADIPOQ/RXRA/COX4I2/AKT3/PPARG/MAPK12/AKT1/CASP7/BID/PIK3R1/UQCRH/LEP/PIK3CB/FOS/ERN1/PIK3R3/PRKAG3/TNFRSF1A/CDC42	19
KEGG	hsa04610	Complement and coagulation cascades	11/868	85/8144	0.2938	0.5489	0.3976	C8A/F2RL3/A2M/VWF/ITGB2/SERPINB2/SERPINC1/CD55/SERPIND1/CFHR3/CFD	11
KEGG	hsa00270	Cysteine and methionine metabolism	7/868	51/8144	0.2983	0.5511	0.3992	LDHB/AHCYL1/CBS/LACC1/SRM/BHMT/LDHAL6B	7
KEGG	hsa00790	Folate biosynthesis	4/868	26/8144	0.2983	0.5511	0.3992	TPH2/TH/MOCOS/AKR1C3	4
KEGG	hsa05224	Breast cancer	18/868	147/8144	0.3016	0.554	0.4013	WNT3/AKT3/CDKN1A/DLL4/AKT1/TCF7L1/CSNK1A1/PIK3R1/MAPK3/TCF7L2/PIK3CB/FOS/FZD2/LRP5/MYC/EGF/PIK3R3/FZD1	18
KEGG	hsa05145	Toxoplasmosis	14/868	112/8144	0.3044	0.556	0.4027	PPIF/ITGA6/HLA-DOB/BIRC7/AKT3/MAPK12/AKT1/JAK1/PIK3CG/MAPK3/LAMA4/LAMA3/IL12B/TNFRSF1A	14
KEGG	hsa05416	Viral myocarditis	8/868	60/8144	0.3063	0.5564	0.403	CAV1/HLA-DOB/ACTG1/FYN/BID/ITGB2/CD55/EIF4G1	8
KEGG	hsa04723	Retrograde endocannabinoid signaling	18/868	148/8144	0.3119	0.5597	0.4054	ADCY9/PLCB1/GNG4/PLCB3/GNB2/MAPK12/GNB4/KCNJ9/GNG10/DAGLA/PLCB4/GABRR3/ADCY5/MAPK3/ADCY4/PRKACA/PRKCB/GRIA1	18
KEGG	hsa04064	NF-kappa B signaling pathway	13/868	104/8144	0.3139	0.5597	0.4054	TRAF5/CSNK2A1/TNFSF14/RIPK1/LCK/MAP3K14/PLCG1/LAT/TAB3/EDARADD/PRKCB/PIAS4/TNFRSF1A	13
KEGG	hsa05206	MicroRNAs in cancer	36/868	310/8144	0.3158	0.5597	0.4054	TNXB/WNT3/FGFR3/MIR99A/HDAC5/MIRLET7A3/HMOX1/MIR106B/MIRLET7C/MIR330/CDKN1A/PDGFRB/MIR326/MIR194-2/MIR205/MIR181A2/PIK3R1/MAPK3/MARCKS/MIR200C/ROCK1/MIRLET7B/PLCG1/MCL1/ZFPM2/ST14/BCL2L2/CCNG1/PIK3CB/MYC/PIM1/SERPINB5/PRKCB/PIK3R3/MIRLET7D/SLC45A3	36
KEGG	hsa04114	Oocyte meiosis	16/868	131/8144	0.3199	0.5597	0.4054	CAMK2G/ADCY9/PPP1CC/CAMK2A/YWHAE/MAPK12/PPP1CA/FBXO5/ADCY5/MAPK3/MAD1L1/PPP3R2/PPP2R5C/SKP1/ADCY4/PRKACA	16
KEGG	hsa04650	Natural killer cell mediated cytotoxicity	16/868	131/8144	0.3199	0.5597	0.4054	ICAM2/LCK/FYN/BID/PIK3R1/MAPK3/ITGB2/PLCG1/LAT/KLRC2/PPP3R2/TNFSF10/VAV2/PIK3CB/PRKCB/PIK3R3	16
KEGG	hsa04514	Cell adhesion molecules	18/868	149/8144	0.3223	0.5597	0.4054	ITGA9/CD276/CLDN16/ITGA6/CLDN15/ICAM2/HLA-DOB/SELPLG/PTPRF/NFASC/NTNG1/SIGLEC1/CNTNAP2/CD34/ITGB2/PECAM1/ICAM3/PDCD1LG2	18
KEGG	hsa00561	Glycerolipid metabolism	8/868	61/8144	0.3227	0.5597	0.4054	ALDH7A1/AGPAT4/LIPG/AGPAT3/DGKZ/DGAT1/DGKE/PNPLA2	8
KEGG	hsa00062	Fatty acid elongation	4/868	27/8144	0.3235	0.5597	0.4054	TECR/ELOVL3/THEM5/PPT1	4
KEGG	hsa04966	Collecting duct acid secretion	4/868	27/8144	0.3235	0.5597	0.4054	SLC4A1/TCIRG1/ATP6V1C1/ATP6V0A1	4
KEGG	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	9/868	70/8144	0.3278	0.5642	0.4086	HBEGF/NOD1/MAPK12/TCIRG1/ATP6V1C1/MAP3K14/PLCG1/CDC42/ATP6V0A1	9
KEGG	hsa00130	Ubiquinone and other terpenoid-quinone biosynthesis	2/868	11/8144	0.3307	0.5661	0.4101	HPD/VKORC1	2
KEGG	hsa05034	Alcoholism	22/868	187/8144	0.3439	0.5857	0.4242	HDAC5/PPP1CC/CAMKK1/GRIN2C/CREB1/GNG4/GNB2/SLC29A1/CREB3L2/GNB4/GNG10/PPP1CA/CREB5/ADCY5/HDAC3/MAPK3/TH/ADORA2A/PRKACA/GRIN3B/GNAS/MAOA	22
KEGG	hsa03022	Basal transcription factors	6/868	45/8144	0.3459	0.5861	0.4245	TAF7L/TAF5L/GTF2H2C/TAF4/TAF1/GTF2E1	6
KEGG	hsa00564	Glycerophospholipid metabolism	12/868	98/8144	0.3504	0.5906	0.4278	PLA2G4B/PLA2G12A/AGPAT4/GPD1/CDS1/AGPAT3/DGKZ/LCAT/LPCAT1/DGKE/CDIPT/GPD2	12
KEGG	hsa04145	Phagosome	18/868	152/8144	0.3541	0.5939	0.4301	SEC61G/MRC2/HLA-DOB/ACTG1/STX18/TCIRG1/ATP6V1C1/TUBB2A/THBS4/ITGB2/LAMP1/NCF2/SEC61A1/SFTPD/TUBA1C/ITGB5/COLEC12/ATP6V0A1	18
KEGG	hsa04137	Mitophagy - animal	9/868	72/8144	0.359	0.5962	0.4318	MITF/MAP1LC3B2/CSNK2A1/RRAS2/MFN1/ATG9B/AMBRA1/BNIP3L/ATG5	9
KEGG	hsa00250	Alanine, aspartate and glutamate metabolism	5/868	37/8144	0.3592	0.5962	0.4318	ABAT/ASS1/GFPT2/GLUD2/GPT	5
KEGG	hsa04115	p53 signaling pathway	9/868	73/8144	0.3747	0.6188	0.4482	CDKN1A/CD82/STEAP3/BID/ZMAT3/SIAH1/CCNG1/TSC2/SERPINB5	9
KEGG	hsa00514	Other types of O-glycan biosynthesis	6/868	47/8144	0.3855	0.6335	0.4588	GXYLT2/GALNT12/ST3GAL3/B4GALT2/LFNG/GALNT13	6
KEGG	hsa04218	Cellular senescence	18/868	156/8144	0.3974	0.6498	0.4706	PPP1CC/AKT3/CDKN1A/CAPN2/MAPK12/RRAS2/AKT1/NFATC3/PPP1CA/PIK3R1/MAPK3/TGFBR1/PPP3R2/PIK3CB/TSC2/MYC/SMAD2/PIK3R3	18
KEGG	hsa04621	NOD-like receptor signaling pathway	21/868	184/8144	0.4038	0.6569	0.4758	TRAF5/P2RX7/PLCB1/MAP1LC3B2/PLCB3/PYCARD/NOD1/YWHAE/MAPK12/MFN1/RIPK1/JAK1/PLCB4/CAMP/MAPK3/TAB3/ATG5/TP53BP1/CARD18/RNASEL/NEK7	21
KEGG	hsa04390	Hippo signaling pathway	18/868	157/8144	0.4084	0.661	0.4788	LIMD1/WNT3/PPP1CC/TP53BP2/ACTG1/YWHAE/TCF7L1/GDF7/PPP1CA/ITGB2/TGFBR1/MOB1A/TCF7L2/FZD2/AMOT/MYC/SMAD2/FZD1	18
KEGG	hsa00220	Arginine biosynthesis	3/868	22/8144	0.4209	0.678	0.4911	ASS1/GLUD2/GPT	3
KEGG	hsa00052	Galactose metabolism	4/868	31/8144	0.4243	0.6802	0.4926	GALK1/MGAM/B4GALT2/PFKP	4
KEGG	hsa05140	Leishmaniasis	9/868	77/8144	0.4379	0.6985	0.5059	HLA-DOB/MAPK12/JAK1/MAPK3/ITGB2/NCF2/IL12B/FOS/PRKCB	9
KEGG	hsa04936	Alcoholic liver disease	16/868	142/8144	0.4464	0.7012	0.5079	ALDH7A1/ADIPOQ/AKT3/MAPK12/AKT1/RIPK1/ACADVL/TCF7L1/MAP3K14/TAB3/IL12B/TCF7L2/PRKAG3/TNFRSF1A/ADH7/ADH1B	16
KEGG	hsa04136	Autophagy - other	4/868	32/8144	0.4491	0.7012	0.5079	ATG9B/ATG4B/ATG5/WIPI2	4
KEGG	hsa04215	Apoptosis - multiple species	4/868	32/8144	0.4491	0.7012	0.5079	BIRC7/CASP7/BID/TNFRSF1A	4
KEGG	hsa03060	Protein export	3/868	23/8144	0.4503	0.7012	0.5079	SEC61G/SPCS2/SEC61A1	3
KEGG	hsa04964	Proximal tubule bicarbonate reclamation	3/868	23/8144	0.4503	0.7012	0.5079	PCK2/GLUD2/FXYD2	3
KEGG	hsa05164	Influenza A	19/868	171/8144	0.4601	0.713	0.5164	PABPN1L/HLA-DOB/AKT3/PYCARD/ACTG1/AKT1/JAK1/BID/PIK3R1/TMPRSS11D/MAPK3/TNFSF10/IL12B/DNAJB1/PIK3CB/PRKCB/RNASEL/PIK3R3/TNFRSF1A	19
KEGG	hsa03018	RNA degradation	9/868	79/8144	0.4693	0.7239	0.5243	TOB2/DCP1B/PARN/CNOT1/TOB1/LSM7/PABPC1L/PFKP/CNOT6L	9
KEGG	hsa00140	Steroid hormone biosynthesis	7/868	61/8144	0.4784	0.7287	0.5278	COMT/CYP11A1/CYP21A2/AKR1C2/CYP19A1/AKR1C3/AKR1C1	7
KEGG	hsa00590	Arachidonic acid metabolism	7/868	61/8144	0.4784	0.7287	0.5278	PLA2G4B/PLA2G12A/ALOX15B/PTGES2/PTGIS/AKR1C3/ALOX12B	7
KEGG	hsa00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	3/868	24/8144	0.4791	0.7287	0.5278	EXT2/EXTL1/EXT1	3
KEGG	hsa04640	Hematopoietic cell lineage	11/868	99/8144	0.4898	0.7384	0.5348	ANPEP/ITGA6/HLA-DOB/CD9/CSF1/ITGA3/CD34/GP5/CD55/CSF1R/FLT3	11
KEGG	hsa00071	Fatty acid degradation	5/868	43/8144	0.49	0.7384	0.5348	ALDH7A1/ACADVL/ACSL1/ADH7/ADH1B	5
KEGG	hsa00982	Drug metabolism - cytochrome P450	8/868	72/8144	0.5065	0.7598	0.5503	ALDH3B1/ALDH3A1/MGST2/GSTT2/MAOA/ADH7/ADH1B/FMO1	8
KEGG	hsa00563	Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	3/868	26/8144	0.5344	0.7943	0.5753	PIGV/PIGO/PIGA	3
KEGG	hsa04950	Maturity onset diabetes of the young	3/868	26/8144	0.5344	0.7943	0.5753	MAFA/PAX6/NEUROD1	3
KEGG	hsa00760	Nicotinate and nicotinamide metabolism	4/868	36/8144	0.544	0.8049	0.583	NMNAT2/NADK/NT5M/NMNAT3	4
KEGG	hsa04350	TGF-beta signaling pathway	10/868	94/8144	0.5523	0.8099	0.5866	DCN/NBL1/GDF7/SMURF1/MAPK3/ROCK1/TGFBR1/SKP1/MYC/SMAD2	10
KEGG	hsa04657	IL-17 signaling pathway	10/868	94/8144	0.5523	0.8099	0.5866	USP25/IL17D/TRAF5/MAPK12/IL17RB/MAPK3/TAB3/S100A9/FOS/IL17B	10
KEGG	hsa01232	Nucleotide metabolism	9/868	85/8144	0.5607	0.8179	0.5924	AK1/AK4/AMPD2/GUK1/LACC1/AK2/DUT/NT5M/CMPK1	9
KEGG	hsa04060	Cytokine-cytokine receptor interaction	31/868	295/8144	0.5628	0.8179	0.5924	IL17D/CCL26/IL12RB2/CSF1/TNFSF14/IL24/IL17RB/GDF7/GHR/PRL/CCR3/IL1RL1/GDF2/IL27RA/CNTFR/TNFSF15/IL32/TGFBR1/IL22RA1/TNFSF10/MSTN/TNFRSF10C/LEP/CXCL14/IL12B/CSF1R/IL17B/CXCR3/TNFRSF1A/TNFRSF19/IL19	31
KEGG	hsa05133	Pertussis	8/868	76/8144	0.5702	0.8251	0.5976	PYCARD/NOD1/MAPK12/CASP7/MAPK3/ITGB2/IL12B/FOS	8
KEGG	hsa05134	Legionellosis	6/868	57/8144	0.5766	0.8305	0.6016	PYCARD/CASP7/ITGB2/CLK1/IL12B/ARF1	6
KEGG	hsa05010	Alzheimer disease	40/868	384/8144	0.5881	0.8418	0.6097	PPIF/PSMB7/WNT3/AGER/PLCB1/COX4I2/ATP2A2/GRIN2C/PLCB3/AKT3/CSNK2A1/CAPN2/CSF1/AKT1/CASP7/TUBB2A/PLCB4/CSNK1A1/BID/DKK4/AMBRA1/PIK3R1/SLC39A7/SLC39A11/UQCRH/MAPK3/PPP3R2/APH1A/APBB1/PIK3CB/ERN1/FZD2/LRP5/RYR3/PIK3R3/TNFRSF1A/WIPI2/TUBA1C/DKK2/FZD1	40
KEGG	hsa00280	Valine, leucine and isoleucine degradation	5/868	48/8144	0.591	0.8418	0.6097	ALDH7A1/OXCT1/HIBADH/ABAT/PCCA	5
KEGG	hsa00480	Glutathione metabolism	6/868	58/8144	0.5941	0.8418	0.6097	GPX4/ANPEP/ODC1/SRM/MGST2/GSTT2	6
KEGG	hsa04714	Thermogenesis	24/868	232/8144	0.5947	0.8418	0.6097	ADCY9/PRDM16/COX4I2/CREB1/SMARCD1/PPARG/ACTG1/MAPK12/CREB3L2/SMARCD2/PLIN1/CREB5/ADCY5/LIPE/UQCRH/ACTL6B/ADCY4/PRKACA/ACSL1/TSC2/NPPA/PNPLA2/GNAS/PRKAG3	24
KEGG	hsa05208	Chemical carcinogenesis - reactive oxygen species	23/868	223/8144	0.6	0.843	0.6106	PPIF/PRKD3/HMOX1/COX4I2/AKT3/MAPK12/AKT1/PTK2/MAP3K14/PIK3R1/UQCRH/MAPK3/NCF2/PRKD1/MGST2/GSTT2/PIK3CB/AKR1C2/FOS/EGF/PIK3R3/AKR1C3/AKR1C1	23
KEGG	hsa04721	Synaptic vesicle cycle	8/868	78/8144	0.6006	0.843	0.6106	SLC6A7/TCIRG1/ATP6V1C1/SNAP25/AP2A2/UNC13A/CLTC/ATP6V0A1	8
KEGG	hsa00513	Various types of N-glycan biosynthesis	4/868	39/8144	0.6093	0.8497	0.6154	MAN1A1/ST3GAL3/MGAT4B/B4GALT2	4
KEGG	hsa04392	Hippo signaling pathway - multiple species	3/868	29/8144	0.6106	0.8497	0.6154	LIMD1/FAT4/MOB1A	3
KEGG	hsa05033	Nicotine addiction	4/868	40/8144	0.6297	0.8726	0.632	GRIN2C/GABRR3/GRIN3B/GRIA1	4
KEGG	hsa00630	Glyoxylate and dicarboxylate metabolism	3/868	30/8144	0.6341	0.873	0.6323	ACSS1/PCCA/ACSS2	3
KEGG	hsa04217	Necroptosis	16/868	159/8144	0.6355	0.873	0.6323	PLA2G4B/CAMK2G/TRAF5/PYCARD/CAPN2/CAMK2A/RIPK1/JAK1/STAT5A/BID/JAK3/GLUD2/TNFSF10/FTH1/RNF103-CHMP3/TNFRSF1A	16
KEGG	hsa04530	Tight junction	17/868	169/8144	0.638	0.873	0.6323	ARPC2/CLDN16/CLDN15/ACTG1/SLC9A3R1/ACTN1/RAPGEF6/ROCK1/PRKACA/MAP3K1/AMOT/ACTN4/PRKAG3/WAS/CDC42/TUBA1C/CFTR	17
KEGG	hsa04710	Circadian rhythm	3/868	31/8144	0.6566	0.8922	0.6462	CREB1/SKP1/PRKAG3	3
KEGG	hsa04141	Protein processing in endoplasmic reticulum	17/868	171/8144	0.6576	0.8922	0.6462	BAG2/SEC61G/CAPN2/SEL1L2/MAN1A1/SEC31B/SIL1/SKP1/DNAJB1/ATXN3/ERN1/SEC61A1/LMAN1L/DNAJA1/EIF2AK1/SVIP/EDEM3	17
KEGG	hsa00380	Tryptophan metabolism	4/868	42/8144	0.6685	0.9033	0.6543	ALDH7A1/TPH2/AANAT/MAOA	4
KEGG	hsa03250	Viral life cycle - HIV-1	6/868	63/8144	0.6757	0.9055	0.6559	MLLT1/NUP153/FURIN/PDCD6IP/ELL/APOBEC3D	6
KEGG	hsa05217	Basal cell carcinoma	6/868	63/8144	0.6757	0.9055	0.6559	WNT3/CDKN1A/TCF7L1/TCF7L2/FZD2/FZD1	6
KEGG	hsa03410	Base excision repair	3/868	33/8144	0.6985	0.9315	0.6747	PARP3/NTHL1/POLD3	3
KEGG	hsa01230	Biosynthesis of amino acids	7/868	75/8144	0.7008	0.9315	0.6747	PYCR2/RPIA/PGK1/CBS/ASS1/PFKP/GPT	7
KEGG	hsa03430	Mismatch repair	2/868	23/8144	0.7201	0.9534	0.6905	MSH6/POLD3	2
KEGG	hsa00230	Purine metabolism	12/868	128/8144	0.7241	0.9548	0.6916	ADCY9/AK1/AK4/AMPD2/GUK1/PDE8A/LACC1/AK2/ADCY5/PDE5A/ADCY4/NT5M	12
KEGG	hsa05162	Measles	13/868	139/8144	0.7325	0.962	0.6968	AKT3/CSNK2A1/AKT1/JAK1/STAT5A/BID/PIK3R1/JAK3/IL12B/PIK3CB/FOS/PIK3R3/EIF2AK1	13
KEGG	hsa00980	Metabolism of xenobiotics by cytochrome P450	7/868	78/8144	0.7393	0.9654	0.6992	ALDH3B1/ALDH3A1/MGST2/GSTT2/ADH7/ADH1B/AKR1C1	7
KEGG	hsa01212	Fatty acid metabolism	5/868	57/8144	0.741	0.9654	0.6992	TECR/ACADVL/ELOVL3/PPT1/ACSL1	5
KEGG	hsa00830	Retinol metabolism	6/868	68/8144	0.7459	0.9679	0.701	DGAT1/CYP26A1/RDH5/CYP27C1/ADH7/ADH1B	6
KEGG	hsa00512	Mucin type O-glycan biosynthesis	3/868	36/8144	0.754	0.9702	0.7027	ST6GALNAC4/GALNT12/GALNT13	3
KEGG	hsa03030	DNA replication	3/868	36/8144	0.754	0.9702	0.7027	MCM6/PRIM2/POLD3	3
KEGG	hsa04080	Neuroactive ligand-receptor interaction	35/868	362/8144	0.7583	0.9702	0.7027	P2RX7/GRIN2C/UTS2R/AVPR1A/GLRA2/P2RY2/RLN3/F2RL3/GHR/PTGER4/HRH1/PRL/GABRR3/PTGER1/PATE2/HRH2/ADORA2A/CYSLTR2/NPFF/HTR1D/PYY/GRM8/LEP/NPBWR2/P2RX3/P2RX5/RLN2/SCT/HRH3/CALCA/GRIN3B/EDN2/POMC/GRIA1/FPR1	35
KEGG	hsa05020	Prion disease	26/868	273/8144	0.7598	0.9702	0.7027	PPIF/PSMB7/CAV1/COX4I2/GRIN2C/CREB1/CSNK2A1/MAPK12/C8A/CREB3L2/TUBB2A/EGR1/FYN/CREB5/CAV3/PIK3R1/UQCRH/MAPK3/NCF2/PPP3R2/PRKACA/PIK3CB/RYR3/GRIN3B/PIK3R3/TUBA1C	26
KEGG	hsa00592	alpha-Linolenic acid metabolism	2/868	25/8144	0.7625	0.9702	0.7027	PLA2G4B/PLA2G12A	2
KEGG	hsa01250	Biosynthesis of nucleotide sugars	3/868	37/8144	0.7705	0.9731	0.7048	GALK1/GNE/GFPT2	3
KEGG	hsa04622	RIG-I-like receptor signaling pathway	6/868	70/8144	0.7707	0.9731	0.7048	MAPK12/RIPK1/SIKE1/ATG5/IL12B/MAP3K1	6
KEGG	hsa04978	Mineral absorption	5/868	60/8144	0.781	0.9792	0.7092	HMOX1/CYBRD1/VDR/FTH1/FXYD2	5
KEGG	hsa00565	Ether lipid metabolism	4/868	49/8144	0.7816	0.9792	0.7092	PLA2G4B/PLA2G12A/GDPD3/LPCAT1	4
KEGG	hsa05323	Rheumatoid arthritis	8/868	93/8144	0.7884	0.984	0.7127	HLA-DOB/CSF1/TCIRG1/ATP6V1C1/ANGPT1/ITGB2/FOS/ATP6V0A1	8
KEGG	hsa05144	Malaria	4/868	50/8144	0.7949	0.9861	0.7142	HBA2/THBS4/ITGB2/PECAM1	4
KEGG	hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	2/868	27/8144	0.7992	0.9861	0.7142	ST3GAL3/B4GALT2	2
KEGG	hsa01040	Biosynthesis of unsaturated fatty acids	2/868	27/8144	0.7992	0.9861	0.7142	TECR/ELOVL3	2
KEGG	hsa00650	Butanoate metabolism	2/868	28/8144	0.8155	0.9958	0.7213	OXCT1/ABAT	2
KEGG	hsa05169	Epstein-Barr virus infection	18/868	202/8144	0.8231	0.9958	0.7213	TRAF5/NCOR2/HLA-DOB/AKT3/CDKN1A/MAPK12/AKT1/RIPK1/JAK1/MAP3K14/BID/PIK3R1/JAK3/RBPJL/PIK3CB/MYC/PIK3R3/CIR1	18
KEGG	hsa03440	Homologous recombination	3/868	41/8144	0.8278	0.9958	0.7213	RAD54L/XRCC3/POLD3	3
KEGG	hsa05022	Pathways of neurodegeneration - multiple diseases	45/868	476/8144	0.8297	0.9958	0.7213	PPIF/CAMK2G/PSMB7/WNT3/AGER/PLCB1/MAP1LC3B2/COX4I2/ATP2A2/GRIN2C/PLCB3/CSNK2A1/CAPN2/CAMK2A/MAPK12/CSF1/UBE2L6/MFN1/CASP7/TUBB2A/PLCB4/CSNK1A1/BID/DKK4/AMBRA1/HIP1/UQCRH/MAPK3/ATXN2/PLCG1/ATXN1/PPP3R2/ATXN3/ERN1/FZD2/LRP5/RYR3/PRKCB/DCTN2/GRIA1/TNFRSF1A/WIPI2/TUBA1C/DKK2/FZD1	45
KEGG	hsa00591	Linoleic acid metabolism	2/868	29/8144	0.8307	0.9958	0.7213	PLA2G4B/PLA2G12A	2
KEGG	hsa04744	Phototransduction	2/868	29/8144	0.8307	0.9958	0.7213	SAG/RCVRN	2
KEGG	hsa00600	Sphingolipid metabolism	4/868	53/8144	0.831	0.9958	0.7213	SMPD2/SGPP1/UGCG/SMPD3	4
KEGG	hsa05202	Transcriptional misregulation in cancer	17/868	193/8144	0.8314	0.9958	0.7213	MITF/RXRA/ETV6/MLLT1/PPARG/CDKN1A/DOT1L/PTK2/ELANE/WT1/ELK4/RUNX1T1/CSF1R/MYC/FLT3/SLC45A3/TLX3	17
KEGG	hsa00430	Taurine and hypotaurine metabolism	1/868	16/8144	0.8355	0.9971	0.7222	FMO1	1
KEGG	hsa00030	Pentose phosphate pathway	2/868	30/8144	0.8448	1	0.7243	RPIA/PFKP	2
KEGG	hsa04940	Type I diabetes mellitus	3/868	43/8144	0.8515	1	0.7243	PTPRN/HLA-DOB/IL12B	3
KEGG	hsa00061	Fatty acid biosynthesis	1/868	18/8144	0.8688	1	0.7243	ACSL1	1
KEGG	hsa00511	Other glycan degradation	1/868	18/8144	0.8688	1	0.7243	MAN2B1	1
KEGG	hsa05171	Coronavirus disease - COVID-19	20/868	232/8144	0.8723	1	0.7243	HBEGF/RPS23/MAPK12/C8A/JAK1/TLR8/RPS26/PIK3R1/VWF/MAPK3/PLCG1/RPS10/IL12B/PIK3CB/FOS/PRKCB/PIK3R3/CFD/TNFRSF1A/RPL29	20
KEGG	hsa02010	ABC transporters	3/868	45/8144	0.8724	1	0.7243	ABCA6/ABCA9/CFTR	3
KEGG	hsa00051	Fructose and mannose metabolism	2/868	33/8144	0.8808	1	0.7243	PFKP/KHK	2
KEGG	hsa04146	Peroxisome	6/868	82/8144	0.8828	1	0.7243	AMACR/PEX5L/ECH1/ACSL1/ACOX2/PEX10	6
KEGG	hsa00531	Glycosaminoglycan degradation	1/868	19/8144	0.8828	1	0.7243	SGSH	1
KEGG	hsa01210	2-Oxocarboxylic acid metabolism	1/868	19/8144	0.8828	1	0.7243	GPT	1
KEGG	hsa03420	Nucleotide excision repair	3/868	47/8144	0.8906	1	0.7243	CETN2/GTF2H2C/POLD3	3
KEGG	hsa00100	Steroid biosynthesis	1/868	20/8144	0.8953	1	0.7243	SQLE	1
KEGG	hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	1/868	20/8144	0.8953	1	0.7243	CHST3	1
KEGG	hsa05150	Staphylococcus aureus infection	7/868	96/8144	0.8985	1	0.7243	HLA-DOB/SELPLG/CAMP/ITGB2/KRT17/CFD/FPR1	7
KEGG	hsa01240	Biosynthesis of cofactors	12/868	153/8144	0.9028	1	0.7243	PPCDC/HPD/NMNAT2/AK1/AK4/AK2/NADK/TPK1/PPOX/NMNAT3/VKORC1/CMPK1	12
KEGG	hsa03015	mRNA surveillance pathway	7/868	97/8144	0.9042	1	0.7243	PABPN1L/PPP1CC/CSTF2/PPP1CA/PPP2R5C/PABPC1L/WDR82	7
KEGG	hsa00520	Amino sugar and nucleotide sugar metabolism	3/868	49/8144	0.9064	1	0.7243	GALK1/GNE/GFPT2	3
KEGG	hsa00770	Pantothenate and CoA biosynthesis	1/868	21/8144	0.9065	1	0.7243	PPCDC	1
KEGG	hsa05016	Huntington disease	26/868	306/8144	0.9139	1	0.7243	PPIF/PSMB7/PLCB1/COX4I2/CREB1/PLCB3/RCOR1/PPARG/CREB3L2/TUBB2A/PLCB4/CREB5/AMBRA1/HIP1/UQCRH/AP2A2/POLR2J2/ERN1/TAF4/POLR2D/DCTN2/CLTC/GRIA1/POLR2C/WIPI2/TUBA1C	26
KEGG	hsa04623	Cytosolic DNA-sensing pathway	4/868	63/8144	0.9152	1	0.7243	PYCARD/RIPK1/POLR3E/TREX1	4
KEGG	hsa00900	Terpenoid backbone biosynthesis	1/868	22/8144	0.9165	1	0.7243	IDI1	1
KEGG	hsa05330	Allograft rejection	2/868	38/8144	0.9241	1	0.7243	HLA-DOB/IL12B	2
KEGG	hsa05340	Primary immunodeficiency	2/868	38/8144	0.9241	1	0.7243	LCK/JAK3	2
KEGG	hsa05321	Inflammatory bowel disease	4/868	65/8144	0.9267	1	0.7243	HLA-DOB/IL12RB2/IL12B/SMAD2	4
KEGG	hsa04612	Antigen processing and presentation	5/868	78/8144	0.9293	1	0.7243	CREB1/HLA-DOB/KLRC2/LGMN/CD74	5
KEGG	hsa04110	Cell cycle	9/868	126/8144	0.9312	1	0.7243	BUB3/CDKN1A/YWHAE/MCM6/FZR1/MAD1L1/SKP1/MYC/SMAD2	9
KEGG	hsa01200	Carbon metabolism	8/868	115/8144	0.9336	1	0.7243	RPIA/PGK1/ACSS1/PCCA/GLUD2/PFKP/GPT/ACSS2	8
KEGG	hsa00983	Drug metabolism - other enzymes	5/868	80/8144	0.9383	1	0.7243	TPMT/DUT/MGST2/GSTT2/CMPK1	5
KEGG	hsa05204	Chemical carcinogenesis - DNA adducts	4/868	69/8144	0.9455	1	0.7243	SULT1A1/MGST2/GSTT2/AKR1C2	4
KEGG	hsa05012	Parkinson disease	21/868	266/8144	0.9485	1	0.7243	PPIF/CAMK2G/PSMB7/COX4I2/CAMK2A/UBE2L6/MFN1/TUBB2A/ADCY5/SLC39A7/SLC39A11/UQCRH/TH/ADORA2A/PLCG1/PRKACA/ERN1/RYR3/GNAS/MAOA/TUBA1C	21
KEGG	hsa03013	Nucleocytoplasmic transport	7/868	108/8144	0.9507	1	0.7243	NMD3/THOC7/SUMO2/NUP153/NUP85/IPO11/NUP35	7
KEGG	hsa00860	Porphyrin metabolism	2/868	43/8144	0.9522	1	0.7243	HMOX1/PPOX	2
KEGG	hsa04975	Fat digestion and absorption	2/868	43/8144	0.9522	1	0.7243	PLA2G12A/DGAT1	2
KEGG	hsa00240	Pyrimidine metabolism	3/868	58/8144	0.955	1	0.7243	DUT/NT5M/CMPK1	3
KEGG	hsa03040	Spliceosome	10/868	147/8144	0.9591	1	0.7243	DHX16/SF3B1/SRSF9/RBM17/PCBP1/SF3B3/CDC5L/PPIH/PUF60/LSM7	10
KEGG	hsa03050	Proteasome	2/868	46/8144	0.964	1	0.7243	PSMB7/POMP	2
KEGG	hsa00020	Citrate cycle (TCA cycle)	1/868	30/8144	0.9662	1	0.7243	PCK2	1
KEGG	hsa00053	Ascorbate and aldarate metabolism	1/868	30/8144	0.9662	1	0.7243	ALDH7A1	1
KEGG	hsa01523	Antifolate resistance	1/868	30/8144	0.9662	1	0.7243	FOLR1	1
KEGG	hsa05310	Asthma	1/868	31/8144	0.9698	1	0.7243	HLA-DOB	1
KEGG	hsa04672	Intestinal immune network for IgA production	2/868	49/8144	0.973	1	0.7243	HLA-DOB/MAP3K14	2
KEGG	hsa04130	SNARE interactions in vesicular transport	1/868	33/8144	0.9759	1	0.7243	STX18	1
KEGG	hsa00500	Starch and sucrose metabolism	1/868	36/8144	0.9829	1	0.7243	MGAM	1
KEGG	hsa03460	Fanconi anemia pathway	2/868	54/8144	0.9833	1	0.7243	FANCE/FANCG	2
KEGG	hsa05332	Graft-versus-host disease	1/868	42/8144	0.9913	1	0.7243	HLA-DOB	1
KEGG	hsa00190	Oxidative phosphorylation	6/868	134/8144	0.997	1	0.7243	COX4I2/TCIRG1/ATP6V1C1/UQCRH/PPA1/ATP6V0A1	6
KEGG	hsa05320	Autoimmune thyroid disease	1/868	53/8144	0.9975	1	0.7243	HLA-DOB	1
KEGG	hsa03008	Ribosome biogenesis in eukaryotes	4/868	109/8144	0.998	1	0.7243	NMD3/CSNK2A1/REXO1/NOP58	4
KEGG	hsa03010	Ribosome	7/868	158/8144	0.9986	1	0.7243	RPS23/MRPS5/RPS26/RPS10/MRPL15/MRPL23/RPL29	7
KEGG	hsa05014	Amyotrophic lateral sclerosis	23/868	364/8144	0.9987	1	0.7243	PSMB7/MATR3/MAP1LC3B2/COX4I2/GRIN2C/ACTG1/NUP153/MAPK12/TUBB2A/BID/AMBRA1/UQCRH/ATXN2/PPP3R2/NUP85/ANXA11/ERN1/DCTN2/GRIA1/TNFRSF1A/NUP35/WIPI2/TUBA1C	23
KEGG	hsa05322	Systemic lupus erythematosus	5/868	136/8144	0.9993	1	0.7243	HLA-DOB/C8A/ACTN1/ELANE/ACTN4	5
KEGG	hsa05168	Herpes simplex virus 1 infection	33/868	495/8144	0.9994	1	0.7243	TRAF5/PPP1CC/ZNF311/HLA-DOB/AKT3/ZNF766/ZNF136/TNFSF14/AKT1/ZNF783/JAK1/SRSF9/BID/PPP1CA/ZNF3/ZNF175/PIK3R1/ZNF135/ZNF454/ZNF461/ZNF786/ZNF705D/IL12B/PIK3CB/TSC2/ZNF620/CD74/RNASEL/PIK3R3/EIF2AK1/TNFRSF1A/ZFP82/ZNF765	33
KEGG	hsa04740	Olfactory transduction	22/868	440/8144	1	1	0.7243	CAMK2G/OR7E24/OR5P3/OR1J1/OR8A1/OR5A1/CAMK2A/OR5K4/OR51B5/OR6P1/ARRB2/OR13C8/NCALD/OR10S1/OR13G1/PRKACA/ARRB1/OR13H1/OR51F2/OR4C46/OR5M10/OR8D2	22