ONTOLOGY	ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	qvalue	geneID	Count
KEGG	hsa04721	Synaptic vesicle cycle	20/836	78/8135	8.353e-05	0.01695	0.01649	AP2M1/AP2S1/ATP6V0D1/ATP6V1H/SYT1/CPLX1/ATP6V0B/SLC1A2/SLC1A7/ATP6V1B2/STX1B/ATP6V1G3/SLC6A7/ATP6V0E2/NAPA/ATP6V1G2/RAB3A/ATP6V0A1/ATP6V1B1/AP2A1	20
KEGG	hsa05323	Rheumatoid arthritis	22/836	93/8135	0.0001377	0.01695	0.01649	ATP6AP1/ACP5/IL18/ATP6V0D1/ATP6V1H/IL11/ATP6V0B/PTH/ATP6V1B2/ITGAL/ATP6V1G3/CD86/MMP3/HLA-DQA1/CD28/ATP6V0E2/ATP6V1G2/HLA-DOB/IL6/ATP6V0A1/ATP6V1B1/CCL3	22
KEGG	hsa04110	Cell cycle	27/836	126/8135	0.0001536	0.01695	0.01649	ANAPC15/TFDP2/SMC3/CCNH/CHEK1/TTK/BUB1/CCNB2/CDKN2B/ANAPC1/BUB1B/YWHAE/CDKN1C/CDC45/TFDP1/CCNB1/CDKN1B/CHEK2/PTTG2/ATR/CCNA1/CREBBP/CCND3/ORC1/CDC20/ANAPC4/MAD2L1	27
KEGG	hsa05166	Human T-cell leukemia virus 1 infection	38/836	222/8135	0.00105	0.08685	0.08451	ANAPC15/STAT5A/ADCY6/MAPK10/IL2/CHEK1/ADCY3/CCNB2/B2M/CDKN2B/ITGAL/ANAPC1/IKBKB/BUB1B/NFYB/PTEN/MSX1/SRF/TLN2/HLA-DQA1/TERT/CHEK2/CREB3L4/PTTG2/ATR/HLA-DOB/CCNA1/CREBBP/IL6/CCND3/HLA-F/NFKB2/EGR2/ADCY8/CDC20/ANAPC4/MAD2L1/RANBP3	38
KEGG	hsa05150	Staphylococcus aureus infection	20/836	96/8135	0.001532	0.1014	0.09869	CFB/C1QB/CFD/C4B/CFH/MASP2/FCGR1A/C4A/FPR3/C1S/MASP1/ITGAL/C1QA/HLA-DQA1/SELPLG/FCGR3B/DEFB4A/C1R/HLA-DOB/FCGR2C	20
KEGG	hsa04610	Complement and coagulation cascades	18/836	85/8135	0.002134	0.1177	0.1146	CFB/C1QB/CFD/C4B/F12/CFH/CFHR1/SERPING1/MASP2/C4A/C1S/MASP1/C1QA/FGA/C8G/A2M/C1R/F8	18
KEGG	hsa00500	Starch and sucrose metabolism	10/836	36/8135	0.002629	0.1243	0.121	AMY1C/AMY2B/TREH/GPI/AMY1A/AMY1B/GANC/AMY2A/HKDC1/PGM2L1	10
KEGG	hsa05110	Vibrio cholerae infection	12/836	50/8135	0.003911	0.1357	0.132	ATP6AP1/ATP6V0D1/ATP6V1H/ATP6V0B/ADCY3/CFTR/ATP6V1B2/ATP6V1G3/ATP6V0E2/ATP6V1G2/ATP6V0A1/ATP6V1B1	12
KEGG	hsa05171	Coronavirus disease - COVID-19	37/836	232/8135	0.004288	0.1357	0.132	CFB/C1QB/CFD/C4B/MASP2/MAPK10/IL2/RPL15/C4A/C1S/MASP1/RPS9/RPS4Y2/IKBKB/MMP3/C1QA/FGA/RPLP1/RPS11/RPS20/RPS27/RPS25/RPL35A/RPS16/C8G/C1R/RPS15A/RPL3L/RPL7/RPL14/RPLP0/STAT1/IL6/RPL38/TRAF6/IFNAR1/RPL21	37
KEGG	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	15/836	70/8135	0.004312	0.1357	0.132	PTPRZ1/LYN/ATP6AP1/ATP6V0D1/MAPK10/ATP6V1H/ATP6V0B/ATP6V1B2/ATP6V1G3/IKBKB/ATP6V0E2/IGSF5/ATP6V1G2/ATP6V0A1/ATP6V1B1	15
KEGG	hsa04966	Collecting duct acid secretion	8/836	27/8135	0.004509	0.1357	0.132	ATP6V0D1/ATP6V1B2/ATP6V1G3/ATP6V0E2/ATP4B/ATP6V1G2/ATP6V0A1/ATP6V1B1	8
KEGG	hsa04115	p53 signaling pathway	15/836	73/8135	0.0065	0.1793	0.1745	RCHY1/SHISA5/CHEK1/CCNB2/PTEN/CCNB1/CHEK2/EI24/GTSE1/STEAP3/SESN1/ATR/CCND3/TP73/PPM1D	15
KEGG	hsa05332	Graft-versus-host disease	10/836	42/8135	0.008644	0.2201	0.2142	IL2/KIR3DL3/KLRC1/CD86/KIR2DL1/HLA-DQA1/CD28/HLA-DOB/IL6/HLA-F	10
KEGG	hsa00603	Glycosphingolipid biosynthesis - globo and isoglobo series	5/836	15/8135	0.01414	0.3343	0.3253	FUT2/FUT1/FUT9/NAGA/A3GALT2	5
KEGG	hsa04914	Progesterone-mediated oocyte maturation	18/836	102/8135	0.01522	0.3359	0.3269	ANAPC15/ADCY6/ARAF/MAPK10/BUB1/ADCY3/CCNB2/GNAI2/ANAPC1/RPS6KA1/INS/CCNB1/SPDYE1/CCNA1/SPDYE16/ADCY8/ANAPC4/MAD2L1	18
KEGG	hsa05221	Acute myeloid leukemia	13/836	67/8135	0.0174	0.36	0.3503	STAT5A/ARAF/FCGR1A/RPS6KB2/PML/MTOR/IKBKB/RARA/JUP/PIM2/PER2/CCNA1/TCF7L1	13
KEGG	hsa04114	Oocyte meiosis	21/836	131/8135	0.02571	0.5006	0.4872	ANAPC15/PPP2R5E/ADCY6/SMC3/CALML6/BUB1/ADCY3/CCNB2/ANAPC1/YWHAE/RPS6KA1/INS/CCNB1/SPDYE1/PTTG2/SPDYE16/ADCY8/CDC20/PPP2R5A/ANAPC4/MAD2L1	21
KEGG	hsa05168	Herpes simplex virus 1 infection	64/836	495/8135	0.02962	0.5427	0.5281	SRSF7/ZNF10/ZNF43/ZNF431/ZNF799/ZNF3/ZNF587/ZNF846/ZNF614/ZNF680/ZNF671/ZNF337/PML/ZNF234/ZNF616/ZNF674/BST2/ZNF514/ZNF549/ZNF195/ZNF304/ZFP69/ZNF107/B2M/ZNF101/ZNF354B/MTOR/ZNF8/IKBKB/ZNF716/ZNF135/ZNF606/ZNF610/ZNF700/ZNF765/ZNF621/ZNF461/ZNF443/HLA-DQA1/ZNF169/SRSF4/ZNF132/BIRC3/ZNF160/ZNF735/ZNF568/ZNF317/ZNF709/ZNF850/ZNF662/ZNF544/ZNF786/ZNF627/ZNF430/ZNF222/ZNF205/HLA-DOB/STAT1/ZNF805/IL6/HLA-F/TRAF6/IFNAR1/ZNF585A	64
KEGG	hsa00511	Other glycan degradation	5/836	18/8135	0.03115	0.5427	0.5281	HEXD/GBA/NEU4/NEU1/MAN2C1	5
KEGG	hsa04928	Parathyroid hormone synthesis, secretion and action	17/836	106/8135	0.04167	0.6392	0.622	ADCY6/ARAF/RUNX2/ADCY3/PTH/GNAI2/PLD2/MEF2A/FGFR1/CREB3L4/SP1/MMP16/SLC34A3/KL/GCM1/ADCY8/VDR	17
KEGG	hsa04930	Type II diabetes mellitus	9/836	46/8135	0.04177	0.6392	0.622	MAPK10/PDX1/PKM/PKLR/MTOR/IKBKB/SLC2A2/INS/HKDC1	9
KEGG	hsa00790	Folate biosynthesis	6/836	26/8135	0.04441	0.6392	0.622	ALPL/PCBD1/MOCS2/CBR1/DHFR2/DHFR	6
KEGG	hsa04950	Maturity onset diabetes of the young	6/836	26/8135	0.04441	0.6392	0.622	PDX1/RFX6/PKLR/SLC2A2/INS/NEUROG3	6
KEGG	hsa00260	Glycine, serine and threonine metabolism	8/836	40/8135	0.0476	0.6517	0.6341	MAOA/AGXT/CBS/CBSL/ALAS1/ALDH7A1/GATM/GNMT	8
KEGG	hsa04213	Longevity regulating pathway - multiple species	11/836	62/8135	0.04922	0.6517	0.6341	ADCY6/RPS6KB2/PRKAA1/ADCY3/HSPA1B/MTOR/FOXO3/INS/HSPA1L/EIF4EBP2/ADCY8	11
KEGG	hsa04612	Antigen processing and presentation	13/836	78/8135	0.05339	0.6798	0.6615	CTSS/KIR3DL3/KLRC1/HSPA1B/B2M/KIR2DS4/NFYB/KIR2DL1/HLA-DQA1/HSPA1L/HLA-DOB/KLRC2/HLA-F	13
KEGG	hsa04145	Phagosome	22/836	152/8135	0.06143	0.7531	0.7328	CTSS/ATP6AP1/TFRC/ATP6V0D1/FCGR1A/RAB5B/ATP6V1H/ATP6V0B/VAMP3/CYBA/ATP6V1B2/ATP6V1G3/HLA-DQA1/FCGR3B/ATP6V0E2/C1R/ATP6V1G2/HLA-DOB/ATP6V0A1/ATP6V1B1/HLA-F/FCGR2C	22
KEGG	hsa00340	Histidine metabolism	5/836	22/8135	0.06812	0.7756	0.7548	MAOA/ALDH3A1/CNDP1/AOC1/ALDH7A1	5
KEGG	hsa04940	Type I diabetes mellitus	8/836	43/8135	0.06853	0.7756	0.7548	IL2/ICA1/CD86/HLA-DQA1/INS/CD28/HLA-DOB/HLA-F	8
KEGG	hsa00350	Tyrosine metabolism	7/836	36/8135	0.0703	0.7756	0.7548	MAOA/AOX1/LRTOMT/ADH1A/ALDH3A1/ADH1C/ADH1B	7
KEGG	hsa04931	Insulin resistance	16/836	108/8135	0.08489	0.8637	0.8405	MAPK10/RPS6KB2/PRKAA1/MLXIPL/GFPT1/MTOR/IKBKB/NR1H2/PTEN/SLC2A2/RPS6KA1/INS/CREB3L4/TRIB3/SLC27A3/IL6	16
KEGG	hsa03010	Ribosome	22/836	158/8135	0.08585	0.8637	0.8405	MRPL34/RPL15/MRPS18C/MRPS21/RPS9/RPS4Y2/RPLP1/RPS11/RPS20/RPS27/RPS25/RPL35A/RPS16/MRPS17/RPS15A/RPL3L/RPL7/RPL14/RPLP0/MRPL1/RPL38/RPL21	22
KEGG	hsa05133	Pertussis	12/836	76/8135	0.08611	0.8637	0.8405	C1QB/C4B/SERPING1/MAPK10/C4A/CALML6/C1S/GNAI2/C1QA/C1R/IL6/TRAF6	12
KEGG	hsa04970	Salivary secretion	14/836	93/8135	0.09241	0.886	0.8622	LYZ/ADCY6/AMY1C/AMY2B/CALML6/ADCY3/AMY1A/AMY1B/CD38/AMY2A/ADRA1B/STATH/ADCY8/SLC4A2	14
KEGG	hsa00130	Ubiquinone and other terpenoid-quinone biosynthesis	3/836	11/8135	0.09541	0.886	0.8622	COQ3/VKORC1/NQO1	3
KEGG	hsa04722	Neurotrophin signaling pathway	17/836	119/8135	0.1006	0.886	0.8622	MAPKAPK2/MAPK10/CALML6/CRKL/FOXO3/IKBKB/YWHAE/RPS6KA1/NTF3/SH2B1/RPS6KA5/NTRK2/SORT1/KIDINS220/TRAF6/TP73/SHC2	17
KEGG	hsa00640	Propanoate metabolism	6/836	32/8135	0.104	0.886	0.8622	ACSS3/MCEE/SUCLA2/ACSS1/HIBCH/EHHADH	6
KEGG	hsa04973	Carbohydrate digestion and absorption	8/836	47/8135	0.104	0.886	0.8622	AMY1C/AMY2B/AMY1A/AMY1B/SLC37A4/SLC2A2/AMY2A/HKDC1	8
KEGG	hsa04380	Osteoclast differentiation	18/836	128/8135	0.1044	0.886	0.8622	ACP5/MAPK10/FCGR1A/CYBA/IKBKB/BLNK/SIRPA/LILRB3/FCGR3B/MITF/MAP2K6/CYLD/TEC/STAT1/NFKB2/TRAF6/IFNAR1/FCGR2C	18
KEGG	hsa05152	Tuberculosis	24/836	180/8135	0.1097	0.8969	0.8728	CTSS/ATP6AP1/IL18/ATP6V0D1/MAPK10/FCGR1A/LBP/RAB5B/CALML6/ATP6V1H/ATP6V0B/MALT1/NFYB/HLA-DQA1/SPHK2/FCGR3B/HLA-DOB/CREBBP/STAT1/IL6/ATP6V0A1/TRAF6/FCGR2C/VDR	24
KEGG	hsa04923	Regulation of lipolysis in adipocytes	9/836	56/8135	0.1161	0.8969	0.8728	PLIN1/ADCY6/ADCY3/GNAI2/PNPLA2/INS/AQP7/ADORA1/ADCY8	9
KEGG	hsa04130	SNARE interactions in vesicular transport	6/836	33/8135	0.1167	0.8969	0.8728	VAMP7/VAMP3/STX1B/VAMP4/STX11/STX17	6
KEGG	hsa04371	Apelin signaling pathway	19/836	139/8135	0.1197	0.8969	0.8728	KLF2/SPP1/PLIN1/ADCY6/PIK3R5/RPS6KB2/PRKAA1/CALML6/ADCY3/GNAI2/MTOR/SLC8A2/SPHK2/MEF2A/ADCY10/BORCS8-MEF2B/MEF2B/ADCY8/TFAM	19
KEGG	hsa05215	Prostate cancer	14/836	97/8135	0.1199	0.8969	0.8728	ARAF/ZEB1/GSTP1/MTOR/IKBKB/MMP3/PTEN/INS/CDKN1B/FGFR1/CREB3L4/CREBBP/PDGFC/TCF7L1	14
KEGG	hsa04211	Longevity regulating pathway	13/836	89/8135	0.1219	0.8969	0.8728	ADCY6/RPS6KB2/EHMT1/PRKAA1/APPL1/ADCY3/MTOR/FOXO3/INS/CREB3L4/SESN1/KL/ADCY8	13
KEGG	hsa00565	Ether lipid metabolism	8/836	49/8135	0.1249	0.8989	0.8748	PLPP3/PLD2/TMEM86B/PLA2G4D/ENPP2/PLB1/GDPD3/PLA2G4A	8
KEGG	hsa04142	Lysosome	18/836	132/8135	0.1293	0.9099	0.8854	LAPTM4B/CTSS/ATP6AP1/ACP5/GNS/ATP6V0D1/GBA/ATP6V1H/ATP6V0B/NEU1/CD164/AP1B1/AP1S3/CD63/NAGA/ATP6V0A1/CTSO/SORT1	18
KEGG	hsa00062	Fatty acid elongation	5/836	27/8135	0.1374	0.9099	0.8854	ACOT4/ELOVL6/HACD4/HACD2/ELOVL1	5
KEGG	hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	5/836	27/8135	0.1374	0.9099	0.8854	ST3GAL6/FUT2/FUT1/FUT9/B3GNT3	5
KEGG	hsa01040	Biosynthesis of unsaturated fatty acids	5/836	27/8135	0.1374	0.9099	0.8854	ACOT4/ELOVL6/HACD4/HACD2/ELOVL1	5
KEGG	hsa00010	Glycolysis / Gluconeogenesis	10/836	67/8135	0.1457	0.9455	0.92	ADH1A/ALDH3A1/ADH1C/PKM/PKLR/GPI/ADH1B/ALDH7A1/ACSS1/HKDC1	10
KEGG	hsa05165	Human papillomavirus infection	40/836	331/8135	0.1553	0.9469	0.9215	SPP1/ATP6AP1/PPP2R5E/ATP6V0D1/PPP2R2B/RPS6KB2/FZD5/ATP6V1H/ATP6V0B/WNT6/PKM/ATP6V1B2/MTOR/ATP6V1G3/RFNG/IKBKB/PTEN/PRKCI/CRB3/TERT/CDKN1B/ATP6V0E2/CREB3L4/COL6A2/ATR/ATP6V1G2/FZD3/RBPJL/CCNA1/CREBBP/STAT1/TCF7L1/LLGL2/ATP6V0A1/ATP6V1B1/CCND3/HLA-F/PPP2R5A/CHAD/IFNAR1	40
KEGG	hsa00512	Mucin type O-glycan biosynthesis	6/836	36/8135	0.159	0.9469	0.9215	GALNT12/GALNT5/GALNT7/GCNT3/B3GNT3/GALNT6	6
KEGG	hsa04935	Growth hormone synthesis, secretion and action	16/836	119/8135	0.1593	0.9469	0.9215	STAT5A/ADCY6/MAPK10/CRKL/ADCY3/GNAI2/MTOR/SSTR1/GHR/ADCY10/CREB3L4/MAP2K6/CREBBP/STAT1/ADCY8/SHC2	16
KEGG	hsa01232	Nucleotide metabolism	12/836	85/8135	0.1595	0.9469	0.9215	NUDT16/DCTPP1/DUT/UPP2/NTPCR/NT5C1A/TK1/AK1/DCK/ASMTL/AK3/LACC1	12
KEGG	hsa04972	Pancreatic secretion	14/836	102/8135	0.1602	0.9469	0.9215	ADCY6/AMY1C/CELA2B/AMY2B/CLCA2/ADCY3/CFTR/AMY1A/AMY1B/CD38/AMY2A/RAB8A/ADCY8/SLC4A2	14
KEGG	hsa05204	Chemical carcinogenesis - DNA adducts	10/836	69/8135	0.1669	0.9691	0.943	EPHX1/GSTP1/NAT2/CYP2C19/CBR1/SULT1A3/SULT1A4/SULT2A1/MGST1/HSD11B1L	10
KEGG	hsa04961	Endocrine and other factor-regulated calcium reabsorption	8/836	53/8135	0.1727	0.97	0.9439	AP2M1/AP2S1/ADCY6/PTH/SLC8A2/KL/AP2A1/VDR	8
KEGG	hsa04218	Cellular senescence	20/836	156/8135	0.1763	0.97	0.9439	TRPV4/MAPKAPK2/CALML6/CHEK1/MYBL2/CCNB2/CDKN2B/MTOR/TRAF3IP2/FOXO3/PTEN/HIPK3/CCNB1/CHEK2/MAP2K6/ATR/CCNA1/IL6/CCND3/HLA-F	20
KEGG	hsa03460	Fanconi anemia pathway	8/836	54/8135	0.1858	0.97	0.9439	CENPS-CORT/TOP3A/POLI/REV3L/FANCA/RAD51/ATR/ATRIP	8
KEGG	hsa01523	Antifolate resistance	5/836	30/8135	0.1895	0.97	0.9439	ALOX12/IKBKB/DHFR2/IL6/DHFR	5
KEGG	hsa05330	Allograft rejection	6/836	38/8135	0.1903	0.97	0.9439	IL2/CD86/HLA-DQA1/CD28/HLA-DOB/HLA-F	6
KEGG	hsa03015	mRNA surveillance pathway	13/836	97/8135	0.1935	0.97	0.9439	PCF11/PPP2R5E/PPP2R2B/PABPN1L/UPF3A/SMG1/BCL2L2-PABPN1/UPF1/PNN/CPSF4L/GLE1/PPP2R5A/FUS	13
KEGG	hsa04666	Fc gamma R-mediated phagocytosis	13/836	97/8135	0.1935	0.97	0.9439	LYN/ACTR2/FCGR1A/RPS6KB2/CRKL/PLPP3/PLD2/WASF3/SPHK2/PLA2G4D/FCGR3B/LIMK1/PLA2G4A	13
KEGG	hsa00310	Lysine degradation	9/836	63/8135	0.1945	0.97	0.9439	SETD2/ASH1L/EHMT1/PRDM16/KMT2B/ALDH7A1/CAMKMT/EHHADH/SETD1A	9
KEGG	hsa00730	Thiamine metabolism	3/836	15/8135	0.1947	0.97	0.9439	ALPL/NTPCR/AK1	3
KEGG	hsa04010	MAPK signaling pathway	35/836	294/8135	0.1987	0.97	0.9439	MAPKAPK2/MAP3K12/CACNB4/ARAF/FGF7/MAPK10/CACNA1H/AREG/CRKL/HSPA1B/MAP3K20/IKBKB/DUSP10/RPS6KA1/NTF3/SRF/INS/FGFR1/PLA2G4D/STK4/RPS6KA5/HSPA1L/MAP2K6/CACNA2D2/VEGFD/NTRK2/RPS6KA4/CACNB2/MAPK8IP2/FGF5/PDGFC/NFKB2/PLA2G4A/PPM1A/TRAF6	35
KEGG	hsa00982	Drug metabolism - cytochrome P450	10/836	72/8135	0.2012	0.97	0.9439	MAOA/AOX1/ADH1A/FMO2/ALDH3A1/GSTP1/ADH1C/ADH1B/CYP2C19/MGST1	10
KEGG	hsa00620	Pyruvate metabolism	7/836	47/8135	0.2036	0.97	0.9439	ADH1A/ADH1C/PKM/PKLR/ADH1B/ALDH7A1/ACSS1	7
KEGG	hsa04120	Ubiquitin mediated proteolysis	18/836	142/8135	0.2051	0.97	0.9439	RCHY1/ANAPC15/MID1/UBE2D4/PML/CUL7/ANAPC1/AIRE/UBE2QL1/BIRC3/UBE2B/RNF7/HERC4/UBE2Q1/CDC20/SMURF2/TRAF6/ANAPC4	18
KEGG	hsa00410	beta-Alanine metabolism	5/836	31/8135	0.2083	0.971	0.945	ALDH3A1/CNDP1/ALDH7A1/HIBCH/EHHADH	5
KEGG	hsa04146	Peroxisome	11/836	82/8135	0.218	0.9922	0.9656	AGXT/CRAT/MPV17/PEX19/PAOX/AMACR/ABCD4/PRDX5/FAR1/NUDT19/EHHADH	11
KEGG	hsa00280	Valine, leucine and isoleucine degradation	7/836	48/8135	0.2188	0.9922	0.9656	AOX1/OXCT1/MCCC2/MCEE/ALDH7A1/HIBCH/EHHADH	7
KEGG	hsa05134	Legionellosis	8/836	57/8135	0.2274	1	0.9731	TLR5/IL18/EEF1A2/HSPA1B/HSPA1L/CLK1/IL6/NFKB2	8
KEGG	hsa04977	Vitamin digestion and absorption	4/836	24/8135	0.2285	1	0.9731	RBP2/LMBRD1/BTD/PLB1	4
KEGG	hsa04672	Intestinal immune network for IgA production	7/836	49/8135	0.2345	1	0.9731	IL2/CD86/HLA-DQA1/CD28/MADCAM1/HLA-DOB/IL6	7
KEGG	hsa03040	Spliceosome	18/836	147/8135	0.2495	1	0.9731	SYF2/SRSF7/PPIE/U2AF1L4/BCAS2/HSPA1B/CWC15/DDX46/SNRPA/SRSF4/PRPF3/HSPA1L/PRPF6/PRPF18/SF3B2/LSM6/FUS/PPIH	18
KEGG	hsa04971	Gastric acid secretion	10/836	76/8135	0.2512	1	0.9731	ADCY6/KCNK2/CALML6/ADCY3/CFTR/GNAI2/KCNJ15/ATP4B/ADCY8/SLC4A2	10
KEGG	hsa05212	Pancreatic cancer	10/836	76/8135	0.2512	1	0.9731	ARAF/MAPK10/RPS6KB2/MTOR/IKBKB/PLD2/RAD51/RALB/RALGDS/STAT1	10
KEGG	hsa00380	Tryptophan metabolism	6/836	42/8135	0.2591	1	0.9731	MAOA/AOX1/KYNU/AOC1/ALDH7A1/EHHADH	6
KEGG	hsa05140	Leishmaniasis	10/836	77/8135	0.2644	1	0.9731	EEF1A2/FCGR1A/PTPN6/CYBA/HLA-DQA1/FCGR3B/HLA-DOB/STAT1/TRAF6/FCGR2C	10
KEGG	hsa00330	Arginine and proline metabolism	7/836	51/8135	0.2668	1	0.9731	MAOA/CKMT2/CNDP1/AOC1/ALDH7A1/GATM/CKB	7
KEGG	hsa04913	Ovarian steroidogenesis	7/836	51/8135	0.2668	1	0.9731	ADCY6/ACOT4/ADCY3/INS/PLA2G4D/ADCY8/PLA2G4A	7
KEGG	hsa05416	Viral myocarditis	8/836	60/8135	0.272	1	0.9731	ITGAL/CD86/HLA-DQA1/CD28/EIF4G3/HLA-DOB/HLA-F/SGCG	8
KEGG	hsa00980	Metabolism of xenobiotics by cytochrome P450	10/836	78/8135	0.2777	1	0.9731	ADH1A/EPHX1/ALDH3A1/GSTP1/ADH1C/ADH1B/CBR1/SULT2A1/MGST1/HSD11B1L	10
KEGG	hsa04140	Autophagy - animal	17/836	141/8135	0.2787	1	0.9731	RAB39B/SUPT20H/ATG9B/MAPK10/RPS6KB2/ATG4B/PRKAA1/MTOR/PTEN/DEPTOR/WIPI1/UVRAG/INS/PRAP1/RAB8A/TRAF6/STX17	17
KEGG	hsa04724	Glutamatergic synapse	14/836	114/8135	0.2803	1	0.9731	ADCY6/ADCY3/SLC1A2/GNAI2/SLC1A7/PLD2/SLC38A2/PLA2G4D/SHANK2/ADCY8/PLA2G4A/GLS/GRIN2A/GRM3	14
KEGG	hsa00600	Sphingolipid metabolism	7/836	52/8135	0.2834	1	0.9731	CERS3/GBA/PLPP3/NEU4/NEU1/SPHK2/KDSR	7
KEGG	hsa00561	Glycerolipid metabolism	8/836	61/8135	0.2873	1	0.9731	LIPF/PLPP3/PNPLA2/DGKA/ALDH7A1/PLPP5/MOGAT2/PNPLA3	8
KEGG	hsa00590	Arachidonic acid metabolism	8/836	61/8135	0.2873	1	0.9731	PTGIS/ALOX12/CYP2C19/CBR1/PLA2G4D/PLB1/PLA2G4A/PTGES	8
KEGG	hsa04936	Alcoholic liver disease	17/836	142/8135	0.2887	1	0.9731	C1QB/C4B/ADH1A/MAPK10/LBP/C4A/PRKAA1/ADH1C/ADH1B/FOXO3/IKBKB/C1QA/ALDH7A1/MAP2K6/TCF7L1/IL6/TRAF6	17
KEGG	hsa03018	RNA degradation	10/836	79/8135	0.2912	1	0.9731	NUDT16/DCP2/BTG3/PATL1/CNOT3/DIS3L/TOB1/EXOSC5/DDX6/LSM6	10
KEGG	hsa05320	Autoimmune thyroid disease	7/836	53/8135	0.3003	1	0.9731	TG/IL2/CD86/HLA-DQA1/CD28/HLA-DOB/HLA-F	7
KEGG	hsa01522	Endocrine resistance	12/836	98/8135	0.3045	1	0.9731	ADCY6/ARAF/MAPK10/RPS6KB2/CARM1/JAG2/ADCY3/MTOR/CDKN1B/SP1/ADCY8/SHC2	12
KEGG	hsa05231	Choline metabolism in cancer	12/836	98/8135	0.3045	1	0.9731	MAPK10/RPS6KB2/PLPP3/MTOR/PLD2/DGKA/WASF3/PLA2G4D/SP1/RALGDS/PDGFC/PLA2G4A	12
KEGG	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	11/836	89/8135	0.305	1	0.9731	RPS6KB2/PTPN6/MTOR/IKBKB/PTEN/ALK/CD28/MAP2K6/STAT1/BATF3/TRAF6	11
KEGG	hsa04630	JAK-STAT signaling pathway	19/836	162/8135	0.3053	1	0.9731	AOX1/IL13RA2/STAT5A/FHL1/IL2/IL5RA/PRLR/THPO/IL11/PTPN6/MTOR/STAM2/GHR/CTF1/CREBBP/STAT1/IL6/CCND3/IFNAR1	19
KEGG	hsa00760	Nicotinate and nicotinamide metabolism	5/836	36/8135	0.3091	1	0.9731	AOX1/SIRT3/NT5C1A/CD38/SIRT5	5
KEGG	hsa04640	Hematopoietic cell lineage	12/836	99/8135	0.317	1	0.9731	TFRC/FCGR1A/IL5RA/THPO/CD44/IL11/HLA-DQA1/CD38/FCER2/HLA-DOB/IL6/GP1BB	12
KEGG	hsa04137	Mitophagy - animal	9/836	72/8135	0.3191	1	0.9731	TOMM7/ATG9B/MAPK10/FIS1/TBC1D17/FOXO3/SP1/MITF/TFEB	9
KEGG	hsa00250	Alanine, aspartate and glutamate metabolism	5/836	37/8135	0.3301	1	0.9731	AGXT/GFPT1/RIMKLB/GPT2/GLS	5
KEGG	hsa01250	Biosynthesis of nucleotide sugars	5/836	37/8135	0.3301	1	0.9731	UAP1L1/GPI/GFPT1/GMPPB/HKDC1	5
KEGG	hsa04621	NOD-like receptor signaling pathway	21/836	184/8135	0.3384	1	0.9731	PSTPIP1/CARD6/IL18/PKN2/MAPK10/CYBA/IKBKB/YWHAE/IFI16/CASP4/GBP2/BIRC3/NEK7/DEFB4A/RIPK3/NLRP1/STAT1/IL6/TRAF6/IFNAR1/GBP3	21
KEGG	hsa00670	One carbon pool by folate	3/836	20/8135	0.3389	1	0.9731	MTHFD1/DHFR2/DHFR	3
KEGG	hsa04916	Melanogenesis	12/836	101/8135	0.3424	1	0.9731	ADCY6/CALML6/FZD5/ADCY3/WNT6/GNAI2/CREB3L4/MITF/FZD3/CREBBP/TCF7L1/ADCY8	12
KEGG	hsa00591	Linoleic acid metabolism	4/836	29/8135	0.3478	1	0.9731	CYP2C19/PLA2G4D/PLB1/PLA2G4A	4
KEGG	hsa04152	AMPK signaling pathway	14/836	120/8135	0.3492	1	0.9731	PPP2R5E/PPP2R2B/RPS6KB2/EEF2K/PRKAA1/CFTR/RAB14/MTOR/FOXO3/INS/RAB8A/CREB3L4/CCNA1/PPP2R5A	14
KEGG	hsa04072	Phospholipase D signaling pathway	17/836	148/8135	0.3509	1	0.9731	ADCY6/PIK3R5/ADCY3/PLPP3/MTOR/PLD2/RALB/DGKA/INS/SPHK2/PLA2G4D/RALGDS/PDGFC/ADCY8/PLA2G4A/GRM3/SHC2	17
KEGG	hsa04144	Endocytosis	28/836	251/8135	0.3509	1	0.9731	VPS28/AP2M1/AGAP5/TFRC/AP2S1/ARAP2/ACTR2/GRK1/IQSEC2/CAV2/RAB5B/PML/RAB31/HSPA1B/AGAP9/STAM2/PLD2/EPN3/PRKCI/RAB8A/HSPA1L/IQSEC3/HLA-F/SMURF2/TRAF6/ARF4/AP2A1/ARF3	28
KEGG	hsa00514	Other types of O-glycan biosynthesis	6/836	47/8135	0.3523	1	0.9731	GALNT12/POMT2/GALNT5/RFNG/GALNT7/GALNT6	6
KEGG	hsa05162	Measles	16/836	139/8135	0.3542	1	0.9731	RCHY1/STAT5A/MAPK10/IL2/HSPA1B/IKBKB/CD28/CDKN1B/HSPA1L/SLAMF1/STAT1/IL6/CCND3/TRAF6/IFNAR1/TP73	16
KEGG	hsa04974	Protein digestion and absorption	12/836	103/8135	0.368	1	0.9731	COL8A1/COL11A2/CELA2B/KCNE3/COL20A1/SLC8A2/SLC38A2/COL6A2/SLC7A7/COL11A1/COL5A3/MEP1A	12
KEGG	hsa04068	FoxO signaling pathway	15/836	131/8135	0.3689	1	0.9731	KLF2/ARAF/MAPK10/PRKAA1/CCNB2/CDKN2B/FOXO3/IKBKB/PTEN/INS/CCNB1/CDKN1B/STK4/CREBBP/IL6	15
KEGG	hsa04620	Toll-like receptor signaling pathway	12/836	104/8135	0.381	1	0.9731	TLR5/SPP1/MAPK10/LBP/IKBKB/CD86/MAP2K6/STAT1/IL6/CCL3/TRAF6/IFNAR1	12
KEGG	hsa04625	C-type lectin receptor signaling pathway	12/836	104/8135	0.381	1	0.9731	MAPKAPK2/MAPK10/IL2/CALML6/IKBKB/MALT1/EGR3/CYLD/STAT1/IL6/NFKB2/EGR2	12
KEGG	hsa00240	Pyrimidine metabolism	7/836	58/8135	0.3867	1	0.9731	DCTPP1/DUT/UPP2/NT5C1A/TK1/DCK/ASMTL	7
KEGG	hsa00520	Amino sugar and nucleotide sugar metabolism	6/836	49/8135	0.3904	1	0.9731	UAP1L1/GPI/GFPT1/GMPPB/NPL/HKDC1	6
KEGG	hsa04611	Platelet activation	14/836	124/8135	0.3967	1	0.9731	LYN/ADCY6/PIK3R5/ADCY3/GNAI2/GP6/FGA/TLN2/PRKCI/PLA2G4D/STIM1/GP1BB/ADCY8/PLA2G4A	14
KEGG	hsa01200	Carbon metabolism	13/836	115/8135	0.4017	1	0.9731	H6PD/PRPS2/AGXT/PKM/PKLR/GPI/MCEE/SUCLA2/ACSS1/HIBCH/HKDC1/GPT2/SDHD	13
KEGG	hsa04015	Rap1 signaling pathway	23/836	210/8135	0.4055	1	0.9731	MAGI2/ADCY6/FGF7/CALML6/RGS14/CRKL/ADCY3/GNAI2/ITGAL/RALB/TLN2/PRKCI/INS/FGFR1/MAP2K6/VEGFD/RALGDS/FGF5/PLCE1/PDGFC/KRIT1/ADCY8/GRIN2A	23
KEGG	hsa03440	Homologous recombination	5/836	41/8135	0.415	1	0.9731	ABRAXAS1/TOP3A/RAD51B/RAD51/POLD2	5
KEGG	hsa04921	Oxytocin signaling pathway	17/836	154/8135	0.4154	1	0.9731	CACNB4/ADCY6/PIK3R5/EEF2K/PRKAA1/CALML6/ADCY3/GNAI2/MYL6B/CAMK1/CD38/PLA2G4D/CACNA2D2/OXTR/CACNB2/ADCY8/PLA2G4A	17
KEGG	hsa04136	Autophagy - other	4/836	32/8135	0.4206	1	0.9731	ATG9B/ATG4B/MTOR/WIPI1	4
KEGG	hsa01521	EGFR tyrosine kinase inhibitor resistance	9/836	79/8135	0.4248	1	0.9731	ARAF/RPS6KB2/MTOR/FOXO3/PTEN/GAS6/PDGFC/IL6/SHC2	9
KEGG	hsa05202	Transcriptional misregulation in cancer	21/836	193/8135	0.4249	1	0.9731	KLF3/FCGR1A/ZEB1/PML/RUNX2/SIX1/PAX5/RARA/CD86/MMP3/CDKN1B/HOXA11/MLLT1/BIRC3/SP1/MITF/JUP/PER2/CCNA1/IL6/FUS	21
KEGG	hsa00515	Mannose type O-glycan biosynthesis	3/836	23/8135	0.426	1	0.9731	POMT2/FUT9/B4GAT1	3
KEGG	hsa03060	Protein export	3/836	23/8135	0.426	1	0.9731	OXA1L/IMMP2L/SRP14	3
KEGG	hsa05322	Systemic lupus erythematosus	15/836	136/8135	0.4267	1	0.9731	C1QB/C4B/FCGR1A/C4A/C1S/CD86/C1QA/RO60/HLA-DQA1/CD28/FCGR3B/C8G/C1R/HLA-DOB/GRIN2A	15
KEGG	hsa04917	Prolactin signaling pathway	8/836	70/8135	0.4316	1	0.9731	STAT5A/MAPK10/PRLR/FOXO3/SLC2A2/INS/STAT1/SHC2	8
KEGG	hsa05230	Central carbon metabolism in cancer	8/836	70/8135	0.4316	1	0.9731	SIRT3/PKM/MTOR/PTEN/SLC2A2/FGFR1/HKDC1/GLS	8
KEGG	hsa03410	Base excision repair	4/836	33/8135	0.4444	1	0.9731	POLD2/PARP4/NEIL1/FEN1	4
KEGG	hsa00071	Fatty acid degradation	5/836	43/8135	0.4569	1	0.9731	ADH1A/ADH1C/ADH1B/ALDH7A1/EHHADH	5
KEGG	hsa05225	Hepatocellular carcinoma	18/836	168/8135	0.4629	1	0.9731	SMARCB1/ARAF/RPS6KB2/GSTP1/FZD5/WNT6/MTOR/SMARCE1/ARID1A/PTEN/NQO1/DPF1/TERT/MGST1/FZD3/ARID2/TCF7L1/SHC2	18
KEGG	hsa04261	Adrenergic signaling in cardiomyocytes	16/836	150/8135	0.4769	1	0.9731	CACNB4/PPP2R5E/ADCY6/PPP2R2B/PIK3R5/CALML6/ADCY3/GNAI2/SLC8A2/CREB3L4/RPS6KA5/CACNA2D2/CACNB2/ADRA1B/ADCY8/PPP2R5A	16
KEGG	hsa04962	Vasopressin-regulated water reabsorption	5/836	44/8135	0.4776	1	0.9731	ADCY6/RAB5B/DYNC2LI1/ADCY3/CREB3L4	5
KEGG	hsa05131	Shigellosis	26/836	247/8135	0.4795	1	0.9731	TLR5/IL18/ACTR2/U2AF1L4/FNBP1/MAPK10/UBE2D4/RPS6KB2/CD44/ILK/CRKL/MTOR/FOXO3/IKBKB/MALT1/CASP4/WIPI1/TLN2/SEPTIN6/TECPR1/FNBP1L/RPS6KA5/DIAPH1/PLCE1/HKDC1/TRAF6	26
KEGG	hsa00592	alpha-Linolenic acid metabolism	3/836	25/8135	0.4818	1	0.9731	PLA2G4D/PLB1/PLA2G4A	3
KEGG	hsa05145	Toxoplasmosis	12/836	112/8135	0.4849	1	0.9731	MAPK10/PIK3R5/HSPA1B/GNAI2/IKBKB/HLA-DQA1/BIRC3/HSPA1L/MAP2K6/HLA-DOB/STAT1/TRAF6	12
KEGG	hsa02010	ABC transporters	5/836	45/8135	0.498	1	0.9731	ABCA12/CFTR/ABCB7/ABCD4/ABCA8	5
KEGG	hsa00360	Phenylalanine metabolism	2/836	16/8135	0.5005	1	0.9731	MAOA/ALDH3A1	2
KEGG	hsa04350	TGF-beta signaling pathway	10/836	94/8135	0.5039	1	0.9731	GDF7/RPS6KB2/CDKN2B/HJV/TFDP1/SP1/FST/CREBBP/SMURF2/SMAD9	10
KEGG	hsa04927	Cortisol synthesis and secretion	7/836	65/8135	0.5077	1	0.9731	ADCY6/KCNK2/CACNA1H/ADCY3/CREB3L4/SP1/ADCY8	7
KEGG	hsa05321	Inflammatory bowel disease	7/836	65/8135	0.5077	1	0.9731	TLR5/IL18/IL2/HLA-DQA1/HLA-DOB/STAT1/IL6	7
KEGG	hsa05169	Epstein-Barr virus infection	21/836	202/8135	0.5124	1	0.9731	LYN/MAPK10/CD44/B2M/ITGAL/IKBKB/BLNK/HLA-DQA1/CDKN1B/MAP2K6/FCER2/RBPJL/HLA-DOB/CCNA1/STAT1/IL6/CCND3/HLA-F/NFKB2/TRAF6/IFNAR1	21
KEGG	hsa04012	ErbB signaling pathway	9/836	85/8135	0.5148	1	0.9731	STAT5A/ARAF/MAPK10/RPS6KB2/AREG/CRKL/MTOR/CDKN1B/SHC2	9
KEGG	hsa00190	Oxidative phosphorylation	14/836	134/8135	0.5162	1	0.9731	ATP6AP1/ATP6V0D1/ATP6V1H/ATP6V0B/UQCRB/ATP6V1B2/ATP6V1G3/ATP12A/ATP6V0E2/ATP4B/ATP6V1G2/ATP6V0A1/ATP6V1B1/SDHD	14
KEGG	hsa05210	Colorectal cancer	9/836	86/8135	0.5295	1	0.9731	ARAF/MAPK10/RPS6KB2/AREG/APPL1/MTOR/RALB/RALGDS/TCF7L1	9
KEGG	hsa05203	Viral carcinogenesis	21/836	204/8135	0.5315	1	0.9731	LYN/STAT5A/MAPKAPK2/ATP6V0D1/CHEK1/PKM/CDKN2B/YWHAE/SRF/CDKN1B/CREB3L4/EGR3/HDAC8/RBPJL/CCNA1/CREBBP/CCND3/HLA-F/NFKB2/EGR2/CDC20	21
KEGG	hsa00120	Primary bile acid biosynthesis	2/836	17/8135	0.5338	1	0.9731	CH25H/AMACR	2
KEGG	hsa01212	Fatty acid metabolism	6/836	57/8135	0.5393	1	0.9731	ELOVL6/HACD4/CBR4/HACD2/ELOVL1/EHHADH	6
KEGG	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	8/836	77/8135	0.5424	1	0.9731	CACNB4/DSC2/SLC8A2/CACNA2D2/JUP/CACNB2/TCF7L1/SGCG	8
KEGG	hsa04150	mTOR signaling pathway	16/836	156/8135	0.5429	1	0.9731	RPS6KB2/PRKAA1/FZD5/ATP6V1H/WNT6/ATP6V1B2/MTOR/ATP6V1G3/IKBKB/PTEN/DEPTOR/RPS6KA1/INS/ATP6V1G2/FZD3/ATP6V1B1	16
KEGG	hsa04713	Circadian entrainment	10/836	97/8135	0.5454	1	0.9731	ADCY6/CACNA1H/CALML6/ADCY3/GNAI2/ADCY10/RPS6KA5/PER2/ADCY8/GRIN2A	10
KEGG	hsa04910	Insulin signaling pathway	14/836	137/8135	0.551	1	0.9731	ARAF/MAPK10/RPS6KB2/PRKAA1/CALML6/CRKL/PKLR/MTOR/PHKA1/IKBKB/PRKCI/INS/HKDC1/SHC2	14
KEGG	hsa05224	Breast cancer	15/836	147/8135	0.5524	1	0.9731	ARAF/FGF7/RPS6KB2/FZD5/JAG2/WNT6/MTOR/PTEN/FGFR1/SP1/FGF5/FZD3/TCF7L1/NFKB2/SHC2	15
KEGG	hsa00564	Glycerophospholipid metabolism	10/836	98/8135	0.559	1	0.9731	LCAT/PLPP3/PNPLA6/PLD2/LPGAT1/DGKA/PLPP5/PLA2G4D/PLB1/PLA2G4A	10
KEGG	hsa04750	Inflammatory mediator regulation of TRP channels	10/836	98/8135	0.559	1	0.9731	TRPV4/ADCY6/MAPK10/CALML6/ADCY3/ALOX12/PLA2G4D/MAP2K6/ADCY8/PLA2G4A	10
KEGG	hsa00230	Purine metabolism	13/836	128/8135	0.5615	1	0.9731	PRPS2/ADCY6/NUDT16/PAPSS1/NTPCR/NT5C1A/ADCY3/AK1/DCK/ADCY10/AK3/LACC1/ADCY8	13
KEGG	hsa04976	Bile secretion	9/836	89/8135	0.5723	1	0.9731	ADCY6/EPHX1/ADCY3/CFTR/SLC51A/SULT2A1/SLC22A8/ADCY8/SLC4A2	9
KEGG	hsa05418	Fluid shear stress and atherosclerosis	14/836	139/8135	0.5738	1	0.9731	KLF2/TRPV4/MAPK10/CAV2/PRKAA1/CALML6/GSTP1/CYBA/IKBKB/NQO1/MEF2A/MGST1/MAP2K6/GPC1	14
KEGG	hsa04330	Notch signaling pathway	6/836	59/8135	0.5742	1	0.9731	JAG2/NCSTN/RFNG/TLE2/RBPJL/CREBBP	6
KEGG	hsa05030	Cocaine addiction	5/836	49/8135	0.5761	1	0.9731	MAOA/GNAI2/CREB3L4/GRIN2A/GRM3	5
KEGG	hsa04744	Phototransduction	3/836	29/8135	0.5848	1	0.9731	GRK1/CALML6/RHO	3
KEGG	hsa04622	RIG-I-like receptor signaling pathway	7/836	70/8135	0.5889	1	0.9731	AZI2/MAPK10/TRIM25/PIN1/IKBKB/CYLD/TRAF6	7
KEGG	hsa05144	Malaria	5/836	50/8135	0.5946	1	0.9731	IL18/LRP1/ITGAL/CD81/IL6	5
KEGG	hsa04520	Adherens junction	7/836	71/8135	0.6043	1	0.9731	PTPN6/SNAI1/WASF3/FGFR1/CREBBP/TCF7L1/SSX2IP	7
KEGG	hsa04014	Ras signaling pathway	23/836	232/8135	0.606	1	0.9731	FGF7/MAPK10/RAB5B/CALML6/IKBKB/PLD2/RASAL3/RALB/NTF3/INS/FGFR1/PLA2G4D/STK4/VEGFD/RALGDS/NTRK2/FGF5/PLCE1/PDGFC/RASSF1/PLA2G4A/GRIN2A/SHC2	23
KEGG	hsa05161	Hepatitis B	16/836	162/8135	0.6061	1	0.9731	STAT5A/ATP6AP1/ARAF/MAPK10/IKBKB/CREB3L4/HSPG2/MAP2K6/EGR3/CCNA1/CREBBP/STAT1/IL6/EGR2/TRAF6/IFNAR1	16
KEGG	hsa00030	Pentose phosphate pathway	3/836	30/8135	0.6084	1	0.9731	H6PD/PRPS2/GPI	3
KEGG	hsa00630	Glyoxylate and dicarboxylate metabolism	3/836	30/8135	0.6084	1	0.9731	AGXT/MCEE/ACSS1	3
KEGG	hsa04668	TNF signaling pathway	11/836	112/8135	0.6099	1	0.9731	MAPK10/IKBKB/MMP3/BIRC3/CREB3L4/RPS6KA5/MAP2K6/VEGFD/RPS6KA4/RIPK3/IL6	11
KEGG	hsa05142	Chagas disease	10/836	102/8135	0.6114	1	0.9731	C1QB/MAPK10/IL2/PPP2R2B/GNAI2/IKBKB/C1QA/IL6/CCL3/TRAF6	10
KEGG	hsa04658	Th1 and Th2 cell differentiation	9/836	92/8135	0.6134	1	0.9731	STAT5A/MAPK10/IL2/JAG2/IKBKB/HLA-DQA1/RBPJL/HLA-DOB/STAT1	9
KEGG	hsa05218	Melanoma	7/836	72/8135	0.6194	1	0.9731	ARAF/FGF7/PTEN/FGFR1/MITF/FGF5/PDGFC	7
KEGG	hsa04912	GnRH signaling pathway	9/836	93/8135	0.6267	1	0.9731	ADCY6/MAPK10/CALML6/ADCY3/PLD2/PLA2G4D/MAP2K6/ADCY8/PLA2G4A	9
KEGG	hsa04270	Vascular smooth muscle contraction	13/836	134/8135	0.6299	1	0.9731	ADCY6/ARAF/CALML6/ADCY3/MYL6B/ADM/RAMP3/PLA2G4D/EDN3/ADRA1B/ADCY8/PLA2G4A/CALCA	13
KEGG	hsa04710	Circadian rhythm	3/836	31/8135	0.6311	1	0.9731	PRKAA1/PER2/NR1D1	3
KEGG	hsa00562	Inositol phosphate metabolism	7/836	73/8135	0.6342	1	0.9731	INPP4A/MTMR8/INPP5J/PTEN/PLCE1/PIK3C2G/MTM1	7
KEGG	hsa04064	NF-kappa B signaling pathway	10/836	104/8135	0.6365	1	0.9731	LYN/LBP/TRIM25/IKBKB/BLNK/MALT1/BIRC3/CYLD/NFKB2/TRAF6	10
KEGG	hsa04934	Cushing syndrome	15/836	155/8135	0.6375	1	0.9731	ARNT/ADCY6/KCNK2/CACNA1H/FZD5/ADCY3/WNT6/GNAI2/CDKN2B/CDKN1B/CREB3L4/SP1/FZD3/TCF7L1/ADCY8	15
KEGG	hsa04657	IL-17 signaling pathway	9/836	94/8135	0.6397	1	0.9731	MAPK10/S100A9/MAPK6/TRAF3IP2/IKBKB/MMP3/DEFB4A/IL6/TRAF6	9
KEGG	hsa03250	Viral life cycle - HIV-1	6/836	63/8135	0.6398	1	0.9731	SMARCB1/BST2/PIN1/MLLT1/ELL2/CREBBP	6
KEGG	hsa04215	Apoptosis - multiple species	3/836	32/8135	0.6529	1	0.9731	MAPK10/BIRC3/SEPTIN4	3
KEGG	hsa04390	Hippo signaling pathway	15/836	157/8135	0.6574	1	0.9731	GDF7/PPP2R2B/AREG/FZD5/WNT6/NKD1/YWHAE/PRKCI/BIRC3/FZD3/TCF7L1/LLGL2/CCND3/RASSF1/TP73	15
KEGG	hsa05135	Yersinia infection	13/836	137/8135	0.6621	1	0.9731	IL18/PKN2/ACTR2/MAPK10/IL2/CRKL/IKBKB/RHOG/RPS6KA1/MAP2K6/LIMK1/IL6/TRAF6	13
KEGG	hsa00920	Sulfur metabolism	1/836	10/8135	0.6621	1	0.9731	PAPSS1	1
KEGG	hsa04911	Insulin secretion	8/836	86/8135	0.6701	1	0.9731	ADCY6/PDX1/ADCY3/SLC2A2/INS/CREB3L4/RAB3A/ADCY8	8
KEGG	hsa00220	Arginine biosynthesis	2/836	22/8135	0.6765	1	0.9731	GPT2/GLS	2
KEGG	hsa05226	Gastric cancer	14/836	149/8135	0.6795	1	0.9731	ARAF/FGF7/RPS6KB2/FZD5/WNT6/CDKN2B/MTOR/TERT/CDKN1B/JUP/FGF5/FZD3/TCF7L1/SHC2	14
KEGG	hsa04659	Th17 cell differentiation	10/836	108/8135	0.6838	1	0.9731	STAT5A/MAPK10/IL2/MTOR/IKBKB/RARA/HLA-DQA1/HLA-DOB/STAT1/IL6	10
KEGG	hsa05100	Bacterial invasion of epithelial cells	7/836	77/8135	0.69	1	0.9731	ACTR2/CAV2/ILK/CRKL/RHOG/SEPTIN6/SHC2	7
KEGG	hsa04151	PI3K-Akt signaling pathway	34/836	354/8135	0.6911	1	0.9731	MAGI2/SPP1/PKN2/PPP2R5E/FGF7/IL2/PPP2R2B/PIK3R5/RPS6KB2/PRLR/PRKAA1/AREG/MTOR/FOXO3/IKBKB/PTEN/GHR/TCL1B/YWHAE/NTF3/INS/CDKN1B/FGFR1/CREB3L4/COL6A2/VEGFD/NTRK2/FGF5/PDGFC/IL6/CCND3/PPP2R5A/CHAD/IFNAR1	34
KEGG	hsa05170	Human immunodeficiency virus 1 infection	20/836	212/8135	0.6924	1	0.9731	MAPK10/RPS6KB2/CALML6/CHEK1/BST2/CRKL/CCNB2/B2M/GNAI2/MTOR/IKBKB/CCNB1/AP1B1/AP1S3/MAP2K6/LIMK1/ATR/RNF7/HLA-F/TRAF6	20
KEGG	hsa04141	Protein processing in endoplasmic reticulum	16/836	171/8135	0.6928	1	0.9731	RNF5/SEC31B/MAPK10/UBE2D4/PDIA6/DERL1/HSPA1B/SEL1L2/SEL1L/ERO1B/HSPA1L/ATXN3/UBQLN2/DERL3/DNAJC1/UBXN4	16
KEGG	hsa05164	Influenza A	16/836	171/8135	0.6928	1	0.9731	IL18/PABPN1L/TMPRSS4/TRIM25/PML/BCL2L2-PABPN1/IKBKB/HLA-DQA1/CPSF4L/HLA-DOB/CREBBP/STAT1/IL6/CCND3/IFNAR1/TPSD1	16
KEGG	hsa03022	Basal transcription factors	4/836	45/8135	0.6932	1	0.9731	GTF2F2/CCNH/TAF7L/TAF10	4
KEGG	hsa04512	ECM-receptor interaction	8/836	88/8135	0.6954	1	0.9731	SPP1/FRAS1/CD44/GP6/HSPG2/COL6A2/GP1BB/CHAD	8
KEGG	hsa04062	Chemokine signaling pathway	18/836	192/8135	0.6965	1	0.9731	LYN/ADCY6/PIK3R5/GRK1/CCL18/FGR/CRKL/ADCY3/GNAI2/CXCR3/FOXO3/IKBKB/CX3CR1/STAT1/CCL3/ADCY8/CCR7/SHC2	18
KEGG	hsa04720	Long-term potentiation	6/836	67/8135	0.6989	1	0.9731	ARAF/CALML6/RPS6KA1/CREBBP/ADCY8/GRIN2A	6
KEGG	hsa03430	Mismatch repair	2/836	23/8135	0.7003	1	0.9731	RFC3/POLD2	2
KEGG	hsa04650	Natural killer cell mediated cytotoxicity	12/836	131/8135	0.7065	1	0.9731	ARAF/NCR1/KIR3DL3/KLRC1/PTPN6/ITGAL/KIR2DS4/KIR2DL1/FCGR3B/KLRC2/IFNAR1/SHC2	12
KEGG	hsa04727	GABAergic synapse	8/836	89/8135	0.7075	1	0.9731	GABRA5/ADCY6/ADCY3/GNAI2/GABRP/SLC38A2/ADCY8/GLS	8
KEGG	hsa04933	AGE-RAGE signaling pathway in diabetic complications	9/836	100/8135	0.7121	1	0.9731	STAT5A/AGER/MAPK10/CDKN1B/VEGFD/DIAPH1/PLCE1/STAT1/IL6	9
KEGG	hsa00830	Retinol metabolism	6/836	68/8135	0.7127	1	0.9731	AOX1/ADH1A/ADH1C/ADH1B/RDH10/RDH8	6
KEGG	hsa01240	Biosynthesis of cofactors	14/836	153/8135	0.7173	1	0.9731	KYNU/COQ3/ALPL/PDXP/MTHFD1/ALAS1/AK1/MOCS2/VKORC1/NQO1/AK3/DHFR2/GMPPB/DHFR	14
KEGG	hsa05213	Endometrial cancer	5/836	58/8135	0.725	1	0.9731	ARAF/ILK/FOXO3/PTEN/TCF7L1	5
KEGG	hsa04924	Renin secretion	6/836	69/8135	0.726	1	0.9731	ADCY6/CLCA2/CALML6/GNAI2/EDN3/ADORA1	6
KEGG	hsa00983	Drug metabolism - other enzymes	7/836	80/8135	0.7281	1	0.9731	DUT/UPP2/GSTP1/TK1/NAT2/TPMT/MGST1	7
KEGG	hsa03030	DNA replication	3/836	36/8135	0.7306	1	0.9731	RFC3/POLD2/FEN1	3
KEGG	hsa04370	VEGF signaling pathway	5/836	59/8135	0.7389	1	0.9731	MAPKAPK2/SPHK2/PLA2G4D/PLA2G4A/SHC2	5
KEGG	hsa04022	cGMP-PKG signaling pathway	15/836	167/8135	0.7478	1	0.9731	ADCY6/PIK3R5/CALML6/ADCY3/GNAI2/SLC8A2/SRF/INS/MEF2A/CREB3L4/BORCS8-MEF2B/MEF2B/ADORA1/ADRA1B/ADCY8	15
KEGG	hsa04662	B cell receptor signaling pathway	7/836	82/8135	0.7516	1	0.9731	LYN/PTPN6/IKBKB/BLNK/MALT1/LILRB3/CD81	7
KEGG	hsa04730	Long-term depression	5/836	60/8135	0.7524	1	0.9731	LYN/ARAF/GNAI2/PLA2G4D/PLA2G4A	5
KEGG	hsa04978	Mineral absorption	5/836	60/8135	0.7524	1	0.9731	MT1G/CLCN2/SLC8A2/SLC34A3/VDR	5
KEGG	hsa03450	Non-homologous end-joining	1/836	13/8135	0.7561	1	0.9731	FEN1	1
KEGG	hsa05223	Non-small cell lung cancer	6/836	72/8135	0.7632	1	0.9731	STAT5A/ARAF/FOXO3/ALK/STK4/RASSF1	6
KEGG	hsa00563	Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	2/836	26/8135	0.7632	1	0.9731	PIGN/PGAP1	2
KEGG	hsa04714	Thermogenesis	21/836	232/8135	0.7643	1	0.9731	SMARCB1/PLIN1/ADCY6/RPS6KB2/PRKAA1/PRDM16/ADCY3/UQCRB/MTOR/SMARCE1/ARID1A/SLC25A29/PNPLA2/DPF1/RPS6KA1/ADCY10/FGFR1/CREB3L4/NDUFAF2/ADCY8/SDHD	21
KEGG	hsa04979	Cholesterol metabolism	4/836	50/8135	0.77	1	0.9731	LCAT/LRP1/LRPAP1/SORT1	4
KEGG	hsa04514	Cell adhesion molecules	13/836	149/8135	0.7738	1	0.9731	CLDN14/ITGAL/CD86/HLA-DQA1/CD28/SELPLG/CD99/CADM3/MADCAM1/HLA-DOB/HLA-F/CLDN18/NFASC	13
KEGG	hsa00513	Various types of N-glycan biosynthesis	3/836	39/8135	0.7795	1	0.9731	HEXD/CHST8/ALG9	3
KEGG	hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	1/836	14/8135	0.7812	1	0.9731	CHST4	1
KEGG	hsa05414	Dilated cardiomyopathy	8/836	96/8135	0.7835	1	0.9731	CACNB4/ADCY6/ADCY3/SLC8A2/CACNA2D2/CACNB2/SGCG/ADCY8	8
KEGG	hsa04623	Cytosolic DNA-sensing pathway	5/836	63/8135	0.7895	1	0.9731	IL18/IKBKB/POLR2H/RIPK3/IL6	5
KEGG	hsa05217	Basal cell carcinoma	5/836	63/8135	0.7895	1	0.9731	FZD5/WNT6/GLI3/FZD3/TCF7L1	5
KEGG	hsa03013	Nucleocytoplasmic transport	9/836	108/8135	0.7929	1	0.9731	EEF1A2/NUP93/UPF3A/TPR/UPF1/NUP155/PNN/GLE1/AHCTF1	9
KEGG	hsa04070	Phosphatidylinositol signaling system	8/836	97/8135	0.7931	1	0.9731	INPP4A/MTMR8/CALML6/PTEN/DGKA/PLCE1/PIK3C2G/MTM1	8
KEGG	hsa04071	Sphingolipid signaling pathway	10/836	119/8135	0.7934	1	0.9731	PPP2R5E/MAPK10/PPP2R2B/CERS3/GNAI2/PTEN/PLD2/SPHK2/ADORA1/PPP2R5A	10
KEGG	hsa05033	Nicotine addiction	3/836	40/8135	0.794	1	0.9731	GABRA5/GABRP/GRIN2A	3
KEGG	hsa01230	Biosynthesis of amino acids	6/836	75/8135	0.7966	1	0.9731	PRPS2/CBS/CBSL/PKM/PKLR/GPT2	6
KEGG	hsa03320	PPAR signaling pathway	6/836	75/8135	0.7966	1	0.9731	PLIN1/ILK/AQP7/APOA5/EHHADH/PLIN4	6
KEGG	hsa05214	Glioma	6/836	75/8135	0.7966	1	0.9731	ARAF/CALML6/MTOR/CAMK1/PTEN/SHC2	6
KEGG	hsa00650	Butanoate metabolism	2/836	28/8135	0.7985	1	0.9731	OXCT1/EHHADH	2
KEGG	hsa04066	HIF-1 signaling pathway	9/836	109/8135	0.8017	1	0.9731	ARNT/TFRC/RPS6KB2/MTOR/INS/CDKN1B/CREBBP/HKDC1/IL6	9
KEGG	hsa00604	Glycosphingolipid biosynthesis - ganglio series	1/836	15/8135	0.8037	1	0.9731	ST3GAL5	1
KEGG	hsa05132	Salmonella infection	22/836	249/8135	0.8052	1	0.9731	TLR5/IL18/ACTR2/MAPK10/RAB5B/DYNC2LI1/CYFIP2/ACTR1A/IKBKB/RHOG/CASP4/WASF3/SNX9/KLC1/BIRC3/MAP2K6/RIPK3/TCF7L1/IL6/PIK3C2G/NCKAP1L/TRAF6	22
KEGG	hsa05220	Chronic myeloid leukemia	6/836	76/8135	0.8069	1	0.9731	STAT5A/ARAF/CRKL/IKBKB/CDKN1B/SHC2	6
KEGG	hsa05219	Bladder cancer	3/836	41/8135	0.8078	1	0.9731	ARAF/RPS6KA5/RASSF1	3
KEGG	hsa04020	Calcium signaling pathway	21/836	240/8135	0.8143	1	0.9731	HTR6/FGF7/CACNA1H/CALML6/ADCY3/PHKA1/CAMK1/SLC8A2/SPHK2/CD38/FGFR1/STIM1/VEGFD/NTRK2/OXTR/ADRA1B/FGF5/PLCE1/PDGFC/ADCY8/GRIN2A	21
KEGG	hsa04061	Viral protein interaction with cytokine and cytokine receptor	8/836	100/8135	0.8199	1	0.9731	IL18/IL2/CCL18/CXCR3/CX3CR1/IL6/CCL3/CCR7	8
KEGG	hsa00430	Taurine and hypotaurine metabolism	1/836	16/8135	0.8239	1	0.9731	FMO2	1
KEGG	hsa04310	Wnt signaling pathway	14/836	167/8135	0.8265	1	0.9731	RNF43/MAPK10/GPC4/RSPO3/FZD5/WNT6/NKD1/SERPINF1/CCN4/TLE2/FZD3/CREBBP/TCF7L1/CCND3	14
KEGG	hsa04024	cAMP signaling pathway	19/836	221/8135	0.8273	1	0.9731	HTR6/ADCY6/MAPK10/CALML6/ADCY3/GLI3/CFTR/GNAI2/PLD2/SSTR1/ADCY10/CREB3L4/OXTR/EDN3/ADORA1/PLCE1/CREBBP/ADCY8/GRIN2A	19
KEGG	hsa00020	Citrate cycle (TCA cycle)	2/836	30/8135	0.8291	1	0.9731	SUCLA2/SDHD	2
KEGG	hsa00053	Ascorbate and aldarate metabolism	2/836	30/8135	0.8291	1	0.9731	ALDH7A1/KL	2
KEGG	hsa05410	Hypertrophic cardiomyopathy	7/836	90/8135	0.831	1	0.9731	CACNB4/PRKAA1/SLC8A2/CACNA2D2/CACNB2/IL6/SGCG	7
KEGG	hsa04975	Fat digestion and absorption	3/836	43/8135	0.833	1	0.9731	LIPF/PLPP3/MOGAT2	3
KEGG	hsa05032	Morphine addiction	7/836	91/8135	0.8394	1	0.9731	GABRA5/ADCY6/ADCY3/GNAI2/GABRP/ADORA1/ADCY8	7
KEGG	hsa04340	Hedgehog signaling pathway	4/836	56/8135	0.8412	1	0.9731	SPOP/GLI3/MOSMO/SMURF2	4
KEGG	hsa04664	Fc epsilon RI signaling pathway	5/836	68/8135	0.8417	1	0.9731	LYN/MAPK10/PLA2G4D/MAP2K6/PLA2G4A	5
KEGG	hsa00450	Selenocompound metabolism	1/836	17/8135	0.842	1	0.9731	PAPSS1	1
KEGG	hsa00052	Galactose metabolism	2/836	31/8135	0.8427	1	0.9731	GANC/HKDC1	2
KEGG	hsa05310	Asthma	2/836	31/8135	0.8427	1	0.9731	HLA-DQA1/HLA-DOB	2
KEGG	hsa04726	Serotonergic synapse	9/836	115/8135	0.8487	1	0.9731	MAOA/HTR6/ARAF/GNAI2/ALOX12/CYP2C19/HTR3D/PLA2G4D/PLA2G4A	9
KEGG	hsa04915	Estrogen signaling pathway	11/836	138/8135	0.8523	1	0.9731	ADCY6/CALML6/ADCY3/HSPA1B/GNAI2/RARA/CREB3L4/HSPA1L/SP1/ADCY8/SHC2	11
KEGG	hsa00061	Fatty acid biosynthesis	1/836	18/8135	0.8583	1	0.9731	CBR4	1
KEGG	hsa00051	Fructose and mannose metabolism	2/836	33/8135	0.8671	1	0.9731	GMPPB/HKDC1	2
KEGG	hsa00531	Glycosaminoglycan degradation	1/836	19/8135	0.8729	1	0.9731	GNS	1
KEGG	hsa01210	2-Oxocarboxylic acid metabolism	1/836	19/8135	0.8729	1	0.9731	GPT2	1
KEGG	hsa03420	Nucleotide excision repair	3/836	47/8135	0.8749	1	0.9731	CCNH/RFC3/POLD2	3
KEGG	hsa00040	Pentose and glucuronate interconversions	2/836	34/8135	0.8779	1	0.9731	DCXR/KL	2
KEGG	hsa01524	Platinum drug resistance	5/836	73/8135	0.8827	1	0.9731	GSTP1/TOP2A/REV3L/MGST1/BIRC3	5
KEGG	hsa04728	Dopaminergic synapse	10/836	132/8135	0.8837	1	0.9731	MAOA/LRTOMT/PPP2R5E/MAPK10/PPP2R2B/CALML6/GNAI2/CREB3L4/PPP2R5A/GRIN2A	10
KEGG	hsa03008	Ribosome biogenesis in eukaryotes	8/836	109/8135	0.8843	1	0.9731	RPP38/WDR75/NAT10/MPHOSPH10/TBL3/NOB1/UTP14A/NOP58	8
KEGG	hsa00100	Steroid biosynthesis	1/836	20/8135	0.886	1	0.9731	FDFT1	1
KEGG	hsa04925	Aldosterone synthesis and secretion	7/836	98/8135	0.8889	1	0.9731	ADCY6/CACNA1H/CALML6/ADCY3/CAMK1/CREB3L4/ADCY8	7
KEGG	hsa04510	Focal adhesion	16/836	201/8135	0.8907	1	0.9731	SPP1/ARHGAP5/MAPK10/CAV2/ILK/CRKL/PTEN/TLN2/BIRC3/COL6A2/VEGFD/DIAPH1/PDGFC/CCND3/CHAD/SHC2	16
KEGG	hsa04918	Thyroid hormone synthesis	5/836	75/8135	0.8963	1	0.9731	TG/ADCY6/ADCY3/CREB3L4/ADCY8	5
KEGG	hsa04530	Tight junction	13/836	169/8135	0.8977	1	0.9731	ACTR2/MAPK10/PPP2R2B/PRKAA1/CFTR/CLDN14/MYL6B/PRKCI/CRB3/RAB8A/IGSF5/LLGL2/CLDN18	13
KEGG	hsa00770	Pantothenate and CoA biosynthesis	1/836	21/8135	0.8977	1	0.9731	VNN1	1
KEGG	hsa05143	African trypanosomiasis	2/836	37/8135	0.9057	1	0.9731	IL18/IL6	2
KEGG	hsa05216	Thyroid cancer	2/836	37/8135	0.9057	1	0.9731	TPR/TCF7L1	2
KEGG	hsa00270	Cysteine and methionine metabolism	3/836	51/8135	0.9073	1	0.9731	CBS/CBSL/LACC1	3
KEGG	hsa05167	Kaposi sarcoma-associated herpesvirus infection	15/836	194/8135	0.9077	1	0.9731	LYN/MAPKAPK2/MAPK10/PIK3R5/CALML6/MTOR/IKBKB/CD86/MAP2K6/CREBBP/STAT1/TCF7L1/IL6/HLA-F/IFNAR1	15
KEGG	hsa05340	Primary immunodeficiency	2/836	38/8135	0.9136	1	0.9731	AIRE/BLNK	2
KEGG	hsa04614	Renin-angiotensin system	1/836	23/8135	0.9177	1	0.9731	PREP	1
KEGG	hsa04964	Proximal tubule bicarbonate reclamation	1/836	23/8135	0.9177	1	0.9731	GLS	1
KEGG	hsa04660	T cell receptor signaling pathway	7/836	104/8135	0.9205	1	0.9731	MAPK10/IL2/PTPN6/IKBKB/MALT1/CD28/TEC	7
KEGG	hsa05222	Small cell lung cancer	6/836	92/8135	0.9219	1	0.9731	CDKN2B/IKBKB/PTEN/CDKN1B/BIRC3/TRAF6	6
KEGG	hsa00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	1/836	24/8135	0.9262	1	0.9731	HS3ST3A1	1
KEGG	hsa05207	Chemical carcinogenesis - receptor activation	16/836	212/8135	0.9303	1	0.9731	STAT5A/ARNT/ADCY6/FGF7/RPS6KB2/EPHX1/ADCY3/GNAI2/MTOR/RPS6KA1/MGST1/CREB3L4/FGF5/CCND3/ADCY8/VDR	16
KEGG	hsa04922	Glucagon signaling pathway	7/836	107/8135	0.9332	1	0.9731	PRKAA1/CALML6/PKM/PHKA1/SLC2A2/CREB3L4/CREBBP	7
KEGG	hsa04216	Ferroptosis	2/836	41/8135	0.9337	1	0.9731	TFRC/STEAP3	2
KEGG	hsa04920	Adipocytokine signaling pathway	4/836	69/8135	0.9341	1	0.9731	MAPK10/PRKAA1/MTOR/IKBKB	4
KEGG	hsa05031	Amphetamine addiction	4/836	69/8135	0.9341	1	0.9731	MAOA/CALML6/CREB3L4/GRIN2A	4
KEGG	hsa05211	Renal cell carcinoma	4/836	69/8135	0.9341	1	0.9731	ARNT/ARAF/CRKL/CREBBP	4
KEGG	hsa05205	Proteoglycans in cancer	15/836	205/8135	0.9427	1	0.9731	ARAF/RPS6KB2/CAV2/FZD5/CD44/WNT6/PTPN6/MTOR/FGFR1/HSPG2/GPC1/CD63/HOXD10/FZD3/PLCE1	15
KEGG	hsa04080	Neuroactive ligand-receptor interaction	28/836	353/8135	0.9463	1	0.9731	KISS1R/GABRA5/SSTR4/P2RY13/HTR6/PRLR/FPR3/NPFFR1/PTH/GALP/PRLHR/NMU/SSTR1/GHR/GABRP/ADM/CHRNA1/OXTR/EDN3/ADORA1/VIPR1/ADRA1B/MC4R/HCRT/CALCA/GRIN2A/NMBR/GRM3	28
KEGG	hsa04742	Taste transduction	5/836	86/8135	0.9494	1	0.9731	GABRA5/ADCY6/HTR3D/TAS2R60/ADCY8	5
KEGG	hsa05130	Pathogenic Escherichia coli infection	14/836	197/8135	0.9515	1	0.9731	TLR5/IL18/ACTR2/MAPK10/CYFIP2/PTPN6/CLDN14/IKBKB/CASP4/WASF3/IL6/NCKAP1L/CLDN18/TRAF6	14
KEGG	hsa04260	Cardiac muscle contraction	5/836	87/8135	0.9527	1	0.9731	CACNB4/UQCRB/SLC8A2/CACNA2D2/CACNB2	5
KEGG	hsa04540	Gap junction	5/836	88/8135	0.9558	1	0.9731	ADCY6/ADCY3/GNAI2/PDGFC/ADCY8	5
KEGG	hsa04670	Leukocyte transendothelial migration	7/836	114/8135	0.956	1	0.9731	ARHGAP5/GNAI2/CLDN14/CYBA/ITGAL/CD99/CLDN18	7
KEGG	hsa04392	Hippo signaling pathway - multiple species	1/836	29/8135	0.9572	1	0.9731	RASSF1	1
KEGG	hsa03050	Proteasome	2/836	46/8135	0.9577	1	0.9731	PSMB11/PSMA8	2
KEGG	hsa05163	Human cytomegalovirus infection	16/836	225/8135	0.9609	1	0.9731	ADCY6/RPS6KB2/CALML6/CRKL/ADCY3/B2M/GNAI2/MTOR/IKBKB/CREB3L4/SP1/MAP2K6/IL6/CCL3/HLA-F/ADCY8	16
KEGG	hsa04926	Relaxin signaling pathway	8/836	129/8135	0.9619	1	0.9731	ADCY6/MAPK10/ADCY3/GNAI2/CREB3L4/VEGFD/ADCY8/SHC2	8
KEGG	hsa05417	Lipid and atherosclerosis	15/836	215/8135	0.964	1	0.9731	LYN/AGER/IL18/MAPK10/LBP/CALML6/HSPA1B/CYBA/IKBKB/MMP3/HSPA1L/MAP2K6/IL6/CCL3/TRAF6	15
KEGG	hsa04929	GnRH secretion	3/836	64/8135	0.9668	1	0.9731	KISS1R/SPP1/CACNA1H	3
KEGG	hsa05160	Hepatitis C	10/836	157/8135	0.968	1	0.9731	ARAF/PPP2R2B/CLDN14/IKBKB/YWHAE/CD81/STAT1/CLDN18/TRAF6/IFNAR1	10
KEGG	hsa04210	Apoptosis	8/836	136/8135	0.975	1	0.9731	CTSS/LMNB1/MAPK10/IKBKB/PARP4/BIRC3/CTSO/SEPTIN4	8
KEGG	hsa03020	RNA polymerase	1/836	34/8135	0.9751	1	0.9731	POLR2H	1
KEGG	hsa05208	Chemical carcinogenesis - reactive oxygen species	15/836	223/8135	0.9756	1	0.9731	ARNT/ARAF/MAPK10/EPHX1/UQCRB/CYBA/FOXO3/IKBKB/PTEN/PLD2/CBR1/NQO1/SLC26A1/MGST1/SDHD	15
KEGG	hsa04060	Cytokine-cytokine receptor interaction	21/836	295/8135	0.9769	1	0.9731	IL13RA2/GDF3/GDF7/IL18/IL2/TNFRSF9/IL5RA/CCL18/PRLR/THPO/IL11/CXCR3/GHR/CTF1/CX3CR1/MSTN/IL6/CCL3/TNFSF15/IFNAR1/CCR7	21
KEGG	hsa04725	Cholinergic synapse	6/836	113/8135	0.98	1	0.9731	ADCY6/PIK3R5/ADCY3/GNAI2/CREB3L4/ADCY8	6
KEGG	hsa04960	Aldosterone-regulated sodium reabsorption	1/836	37/8135	0.9821	1	0.9731	INS	1
KEGG	hsa04932	Non-alcoholic fatty liver disease	9/836	155/8135	0.9828	1	0.9731	MAPK10/PRKAA1/MLXIPL/UQCRB/PKLR/IKBKB/INS/IL6/SDHD	9
KEGG	hsa04810	Regulation of actin cytoskeleton	14/836	218/8135	0.9831	1	0.9731	ACTR2/ARAF/FGF7/IQGAP3/CYFIP2/CRKL/ITGAL/INS/FGFR1/LIMK1/FGF5/DIAPH1/PDGFC/NCKAP1L	14
KEGG	hsa05017	Spinocerebellar ataxia	8/836	143/8135	0.9839	1	0.9731	MAPK10/MTOR/PSMA8/WIPI1/SP1/ATXN3/RBPJL/GRIN2A	8
KEGG	hsa04360	Axon guidance	11/836	182/8135	0.9843	1	0.9731	GDF7/ABLIM1/EPHA5/ILK/GNAI2/EPHA1/SEMA4F/EPHA7/LIMK1/SEMA3A/FZD3	11
KEGG	hsa05014	Amyotrophic lateral sclerosis	26/836	364/8135	0.9857	1	0.9731	SRSF7/RAB39B/SETX/SIGMAR1/TOMM40/DERL1/NUP93/SLC1A2/ACTR1A/UQCRB/MTOR/TPR/PSMA8/NEFH/NUP155/WIPI1/KLC1/CCS/RAB8A/ANG/MAP2K6/GLE1/UBQLN2/FUS/GRIN2A/SDHD	26
KEGG	hsa00480	Glutathione metabolism	2/836	58/8135	0.986	1	0.9731	GSTP1/MGST1	2
KEGG	hsa04217	Necroptosis	9/836	159/8135	0.9866	1	0.9731	STAT5A/MAPK10/PLA2G4D/BIRC3/CYLD/RIPK3/STAT1/PLA2G4A/IFNAR1	9
KEGG	hsa00140	Steroid hormone biosynthesis	2/836	61/8135	0.9895	1	0.9731	LRTOMT/HSD11B1L	2
KEGG	hsa04613	Neutrophil extracellular trap formation	11/836	190/8135	0.9902	1	0.9731	AGER/FCGR1A/FPR3/CYBA/ITGAL/MTOR/FGA/CASP4/SELPLG/FCGR3B/HDAC8	11
KEGG	hsa00860	Porphyrin metabolism	1/836	43/8135	0.9907	1	0.9731	ALAS1	1
KEGG	hsa00970	Aminoacyl-tRNA biosynthesis	2/836	66/8135	0.9935	1	0.9731	QRSL1/VARS2	2
KEGG	hsa04550	Signaling pathways regulating pluripotency of stem cells	7/836	143/8135	0.9935	1	0.9731	FZD5/KAT6A/WNT6/FGFR1/NEUROG1/FZD3/SMAD9	7
KEGG	hsa05034	Alcoholism	10/836	187/8135	0.9947	1	0.9731	MAOA/ARAF/CALML6/GNAI2/CREB3L4/NTRK2/HDAC8/SLC29A3/GRIN2A/SHC2	10
KEGG	hsa04723	Retrograde endocannabinoid signaling	7/836	148/8135	0.9955	1	0.9731	GABRA5/ADCY6/MAPK10/ADCY3/GNAI2/GABRP/ADCY8	7
KEGG	hsa05415	Diabetic cardiomyopathy	11/836	203/8135	0.9956	1	0.9731	PDK4/AGER/MAPK10/UQCRB/CYBA/GFPT1/MTOR/PTEN/INS/SP1/SDHD	11
KEGG	hsa00510	N-Glycan biosynthesis	1/836	50/8135	0.9957	1	0.9731	ALG9	1
KEGG	hsa04919	Thyroid hormone signaling pathway	5/836	121/8135	0.9962	1	0.9731	MED13/MTOR/PLCE1/CREBBP/STAT1	5
KEGG	hsa05020	Prion disease	15/836	273/8135	0.9985	1	0.9731	C1QB/MAPK10/CAV2/HSPA1B/UQCRB/CYBA/C1QA/PSMA8/KLC1/C8G/CREB3L4/HSPA1L/IL6/GRIN2A/SDHD	15
KEGG	hsa05146	Amoebiasis	3/836	102/8135	0.9988	1	0.9731	RAB5B/C8G/IL6	3
KEGG	hsa05016	Huntington disease	17/836	306/8135	0.999	1	0.9731	AP2M1/AP2S1/MAPK10/SLC1A2/ACTR1A/UQCRB/MTOR/PSMA8/POLR2H/WIPI1/KLC1/CREB3L4/SP1/CREBBP/TFAM/SDHD/AP2A1	17
KEGG	hsa05206	MicroRNAs in cancer	17/836	310/8135	0.9992	1	0.9731	ZEB1/DICER1/CD44/IGF2BP1/CRKL/KIF23/MTOR/IKBKB/PTEN/CDKN1B/RPS6KA5/HOXD10/MMP16/FZD3/CREBBP/RASSF1/GLS	17
KEGG	hsa05010	Alzheimer disease	20/836	384/8135	0.9999	1	0.9731	AGER/ARAF/MAPK10/CALML6/FZD5/BACE2/LRP1/WNT6/NCSTN/UQCRB/MTOR/IKBKB/PSMA8/WIPI1/INS/KLC1/FZD3/IL6/GRIN2A/SDHD	20
KEGG	hsa05022	Pathways of neurodegeneration - multiple diseases	27/836	476/8135	0.9999	1	0.9731	RAB39B/AGER/ARAF/MAPK10/CALML6/SIGMAR1/FZD5/TOMM40/DERL1/WNT6/ACTR1A/UQCRB/MTOR/PSMA8/NEFH/WIPI1/KLC1/CCS/RAB8A/PARK7/MAP2K6/ATXN3/FZD3/IL6/FUS/GRIN2A/SDHD	27
KEGG	hsa05012	Parkinson disease	9/836	266/8135	1	1	0.9731	MAOA/MAPK10/CALML6/GNAI2/UQCRB/PSMA8/KLC1/PARK7/SDHD	9
KEGG	hsa04740	Olfactory transduction	17/836	440/8135	1	1	0.9731	OR8S1/OR10A2/OR4D6/OR10A5/OR4K5/CALML6/OR2G2/OR8H1/ADCY3/OR1A2/OR2H1/OR13J1/SLC8A2/OR52I1/OR52A5/OR10H4/OR52B2	17