ONTOLOGY	ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	qvalue	geneID	Count
KEGG	hsa05132	Salmonella infection	29/354	249/8135	1.08e-06	0.0003261	0.0002784	TUBB6/MAPK14/KIF5B/IRAK4/TCF7L2/TUBA1C/RHOB/TUBA1B/MYC/ARL8B/FADD/FLNC/NLRC4/TNF/MAP2K1/TUBA4A/TUBB3/MAPK11/NAIP/TNFRSF1A/DCTN4/TUBB/TUBA1A/MAPK13/S100A10/KPNA1/TUBA8/TUBB4B/NOD1	29
KEGG	hsa04210	Apoptosis	19/354	136/8135	5.986e-06	0.0009039	0.0007719	TUBA1C/TUBA1B/FADD/GADD45A/MAP3K14/TNF/MAP2K1/DDIT3/TUBA4A/LMNB2/EIF2S1/TNFRSF1A/BCL2L11/CASP10/TUBA1A/PDPK1/NTRK1/TUBA8/APAF1	19
KEGG	hsa04071	Sphingolipid signaling pathway	17/354	119/8135	1.374e-05	0.001383	0.001181	MAPK14/SGPL1/PLD1/TNF/PPP2R1B/MAP2K1/SGMS2/ADORA3/MAPK11/TNFRSF1A/ADORA1/PTEN/PDPK1/CERS6/MAPK13/PRKCA/SPTLC1	17
KEGG	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	12/354	70/8135	4.152e-05	0.002585	0.002208	MAPK14/ATP6V1C1/MAP3K14/ATP6V1B2/MAPK11/CSK/ATP6V0A4/ATP6V0E2/ATP6V1E1/MAPK13/ATP6V1A/NOD1	12
KEGG	hsa05130	Pathogenic Escherichia coli infection	22/354	197/8135	4.28e-05	0.002585	0.002208	EZR/TUBB6/MAPK14/IRAK4/TUBA1C/TUBA1B/FADD/SLC9A3R1/TNF/SEC24A/TUBA4A/TUBB3/MAPK11/WASF1/NAIP/TNFRSF1A/TUBB/TUBA1A/OCLN/MAPK13/TUBA8/TUBB4B	22
KEGG	hsa04145	Phagosome	18/354	152/8135	1e-04	0.005034	0.004299	TUBB6/TUBA1C/TUBA1B/ITGAM/ATP6V1C1/ATP6V1B2/STX12/STX7/TUBA4A/TUBB3/ATP6V0A4/ATP6V0E2/TUBB/TUBA1A/ATP6V1E1/ATP6V1A/TUBA8/TUBB4B	18
KEGG	hsa00770	Pantothenate and CoA biosynthesis	6/354	21/8135	0.0002025	0.008736	0.00746	VNN1/PPCDC/DPYD/ALDH2/PANK3/BCAT1	6
KEGG	hsa04966	Collecting duct acid secretion	6/354	27/8135	0.0008852	0.02945	0.02515	ATP6V1C1/ATP6V1B2/ATP6V0A4/ATP6V0E2/ATP6V1E1/ATP6V1A	6
KEGG	hsa05216	Thyroid cancer	7/354	37/8135	0.0009255	0.02945	0.02515	TCF7L2/CCDC6/MYC/GADD45A/MAP2K1/NTRK1/CDKN1A	7
KEGG	hsa04010	MAPK signaling pathway	25/354	294/8135	0.0009927	0.02945	0.02515	CSF1R/MAPK14/IRAK4/NFATC3/ARRB1/MYC/FLNC/GADD45A/MAP4K1/MAP3K14/TNF/PPM1B/FGF8/MAP2K1/DDIT3/DUSP5/DUSP2/MAPK11/TNFRSF1A/MAP4K4/MAPK13/NTRK1/PRKCA/SRF/DUSP7	25
KEGG	hsa04610	Complement and coagulation cascades	11/354	85/8135	0.001073	0.02945	0.02515	SERPINB2/CFD/ITGAM/F5/F2RL3/F8/C4BPA/C5/PLAUR/CR1/SERPINA5	11
KEGG	hsa04540	Gap junction	11/354	88/8135	0.001433	0.03606	0.03079	TUBB6/TUBA1C/TUBA1B/MAP2K1/TUBA4A/TUBB3/TUBB/TUBA1A/TUBA8/PRKCA/TUBB4B	11
KEGG	hsa05161	Hepatitis B	16/354	162/8135	0.001787	0.04151	0.03545	MAPK14/DDX3X/IRAK4/NFATC3/MYC/FADD/TNF/MAP2K1/MAPK11/IKBKE/CASP10/MAPK13/PRKCA/APAF1/EGR3/CDKN1A	16
KEGG	hsa04664	Fc epsilon RI signaling pathway	9/354	68/8135	0.002569	0.05542	0.04732	MAPK14/ALOX5AP/TNF/MAP2K1/MAPK11/VAV3/PDPK1/MAPK13/PRKCA	9
KEGG	hsa05169	Epstein-Barr virus infection	18/354	202/8135	0.003001	0.06043	0.0516	MAPK14/IRAK4/MYC/FADD/GADD45A/MAP3K14/TNF/ITGAL/NFKBIE/MAPK11/MDM2/IKBKE/BCL2L11/RUNX3/MAPK13/SAP30/APAF1/CDKN1A	18
KEGG	hsa04936	Alcoholic liver disease	14/354	142/8135	0.003446	0.06504	0.05554	FOXO1/MAPK14/IRAK4/TCF7L2/FADD/MAP3K14/TNF/MAPK11/TNFRSF1A/IKBKE/PPARA/ALDH2/C5/MAPK13	14
KEGG	hsa05022	Pathways of neurodegeneration - multiple diseases	33/354	476/8135	0.0051	0.07517	0.06419	TUBB6/FRAT1/MAPK14/KIF5B/CDK5R1/FRAT2/FIG4/TUBA1C/TUBA1B/PSEN1/FADD/HIP1/TNFRSF1B/TNF/NDUFV1/MAP2K1/DDIT3/TUBA4A/TUBB3/EIF2S1/MAPK11/TNFRSF1A/DCTN4/CAMK2G/TUBB/TUBA1A/MAPK13/TUBA8/PRKCA/APAF1/TUBB4B/LRRK2/ATG101	33
KEGG	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	10/354	89/8135	0.005103	0.07517	0.06419	IFNGR1/MAPK14/NFATC3/MAP2K1/BATF/NFKBIE/MAPK11/PTEN/MAPK13/BATF2	10
KEGG	hsa05152	Tuberculosis	16/354	180/8135	0.005136	0.07517	0.06419	IFNGR1/MAPK14/IRAK4/FADD/ITGAM/TNF/MAPK11/IL10RA/TNFRSF1A/CLEC4E/CASP10/ATP6V0A4/CAMK2G/MAPK13/CR1/APAF1	16
KEGG	hsa04625	C-type lectin receptor signaling pathway	11/354	104/8135	0.005383	0.07517	0.06419	MAPK14/NFATC3/CLEC4D/MAP3K14/TNF/MAPK11/MDM2/CLEC4E/IKBKE/MAPK13/EGR3	11
KEGG	hsa05133	Pertussis	9/354	76/8135	0.005479	0.07517	0.06419	MAPK14/IRAK4/ITGAM/TNF/MAPK11/C4BPA/C5/MAPK13/NOD1	9
KEGG	hsa05110	Vibrio cholerae infection	7/354	50/8135	0.005533	0.07517	0.06419	ATP6V1C1/ATP6V1B2/ATP6V0A4/ATP6V0E2/ATP6V1E1/ATP6V1A/PRKCA	7
KEGG	hsa05417	Lipid and atherosclerosis	18/354	215/8135	0.005792	0.07517	0.06419	MAPK14/IRAK4/NFATC3/POU2F2/TNF/LDLR/DDIT3/EIF2S1/MAPK11/TNFRSF1A/IKBKE/VAV3/CAMK2G/PDPK1/MAPK13/CCL2/PRKCA/APAF1	18
KEGG	hsa05140	Leishmaniasis	9/354	77/8135	0.005974	0.07517	0.06419	IFNGR1/MAPK14/IRAK4/ITGAM/TNF/MAPK11/MARCKSL1/MAPK13/CR1	9
KEGG	hsa05323	Rheumatoid arthritis	10/354	93/8135	0.006959	0.08407	0.07179	ATP6V1C1/TNF/ATP6V1B2/ITGAL/ATP6V0A4/ATP6V0E2/ATP6V1E1/ATP6V1A/CCL2/LTB	10
KEGG	hsa05164	Influenza A	15/354	171/8135	0.007476	0.08684	0.07416	IFNGR1/IRAK4/FADD/TNF/MAP2K1/RNASEL/EIF2S1/NXT1/TNFRSF1A/IKBKE/NXT2/KPNA1/CCL2/PRKCA/APAF1	15
KEGG	hsa05205	Proteoglycans in cancer	17/354	205/8135	0.007924	0.08863	0.07569	EZR/MAPK14/MYC/FLNC/TNF/MAP2K1/RDX/MAPK11/MDM2/VAV3/CBL/CAMK2G/PLAUR/PDPK1/MAPK13/PRKCA/CDKN1A	17
KEGG	hsa05160	Hepatitis C	14/354	157/8135	0.008352	0.08927	0.07623	MYC/FADD/TNF/PPP2R1B/MAP2K1/RNASEL/LDLR/EIF2S1/TNFRSF1A/IKBKE/PPARA/OCLN/APAF1/CDKN1A	14
KEGG	hsa05014	Amyotrophic lateral sclerosis	26/354	364/8135	0.008572	0.08927	0.07623	TUBB6/MAPK14/KIF5B/FIG4/TUBA1C/TUBA1B/TNFRSF1B/TNF/NDUFV1/DDIT3/TUBA4A/TUBB3/EIF2S1/MAPK11/NXT1/TNFRSF1A/DCTN4/TUBB/TUBA1A/MAPK13/NXT2/TUBA8/APAF1/TUBB4B/ATG101/NUP62	26
KEGG	hsa04668	TNF signaling pathway	11/354	112/8135	0.009311	0.08987	0.07674	MAPK14/FADD/MAP3K14/TNFRSF1B/TNF/MAP2K1/MAPK11/TNFRSF1A/CASP10/MAPK13/CCL2	11
KEGG	hsa05145	Toxoplasmosis	11/354	112/8135	0.009311	0.08987	0.07674	IFNGR1/MAPK14/IRAK4/TNF/LDLR/MAPK11/LAMA5/IL10RA/TNFRSF1A/PDPK1/MAPK13	11
KEGG	hsa05165	Human papillomavirus infection	24/354	331/8135	0.009523	0.08987	0.07674	FOXO1/CHD4/TCF7L2/PSEN1/FADD/SLC9A3R1/ATP6V1C1/HES4/TNF/PPP2R1B/MAP2K1/LFNG/ATP6V1B2/LAMA5/MDM2/TNFRSF1A/IKBKE/ATP6V0A4/PTEN/ATP6V0E2/ATP6V1E1/MAML3/ATP6V1A/CDKN1A	24
KEGG	hsa04015	Rap1 signaling pathway	17/354	210/8135	0.00997	0.09124	0.07792	CSF1R/MAPK14/ADORA2B/ITGAM/F2RL3/FGF8/MAP2K1/SIPA1L2/TLN1/ITGAL/FPR1/MAPK11/RALB/VAV3/EVL/MAPK13/PRKCA	17
KEGG	hsa04622	RIG-I-like receptor signaling pathway	8/354	70/8135	0.01064	0.09452	0.08072	MAPK14/DDX3X/FADD/TNF/MAPK11/IKBKE/CASP10/MAPK13	8
KEGG	hsa04061	Viral protein interaction with cytokine and cytokine receptor	10/354	100/8135	0.01142	0.09852	0.08413	CSF1R/TNFRSF1B/TNF/PF4V1/IL10RA/TNFRSF1A/TNFSF14/CCR2/CCL2/CCL13	10
KEGG	hsa05213	Endometrial cancer	7/354	58/8135	0.01239	0.104	0.08878	TCF7L2/MYC/GADD45A/MAP2K1/PTEN/PDPK1/CDKN1A	7
KEGG	hsa05142	Chagas disease	10/354	102/8135	0.01302	0.1063	0.09075	IFNGR1/MAPK14/IRAK4/FADD/TNF/PPP2R1B/MAPK11/TNFRSF1A/MAPK13/CCL2	10
KEGG	hsa00562	Inositol phosphate metabolism	8/354	73/8135	0.01355	0.1077	0.09194	FIG4/PI4KA/MTMR4/ITPKB/ITPKC/MTMR3/PTEN/PIP5K1C	8
KEGG	hsa04722	Neurotrophin signaling pathway	11/354	119/8135	0.01431	0.1108	0.0946	MAPK14/IRAK4/SH2B3/PSEN1/MAP2K1/NFKBIE/MAPK11/CAMK2G/PDPK1/MAPK13/NTRK1	11
KEGG	hsa04660	T cell receptor signaling pathway	10/354	104/8135	0.01479	0.1116	0.09534	MAPK14/NFATC3/MAP3K14/TNF/MAP2K1/NFKBIE/MAPK11/VAV3/PDPK1/MAPK13	10
KEGG	hsa05214	Glioma	8/354	75/8135	0.01578	0.1162	0.09927	CAMK1D/GADD45A/MAP2K1/MDM2/PTEN/CAMK2G/PRKCA/CDKN1A	8
KEGG	hsa04613	Neutrophil extracellular trap formation	15/354	190/8135	0.01846	0.1327	0.1133	FPR2/AQP9/MAPK14/ITGAM/HDAC5/MAP2K1/ITGAL/ELANE/FPR1/MAPK11/C5/CLCN4/MAPK13/CR1/PRKCA	15
KEGG	hsa04657	IL-17 signaling pathway	9/354	94/8135	0.02074	0.1439	0.1229	MAPK14/FADD/TRAF4/TNF/MAPK11/IL17B/IKBKE/MAPK13/CCL2	9
KEGG	hsa05202	Transcriptional misregulation in cancer	15/354	193/8135	0.02096	0.1439	0.1229	CSF1R/FOXO1/SMAD1/MYC/ITGAM/GADD45A/IL1R2/ETV6/ELANE/DDIT3/MDM2/NTRK1/TCF3/KLF3/CDKN1A	15
KEGG	hsa04068	FoxO signaling pathway	11/354	131/8135	0.02723	0.1828	0.1561	FOXO1/MAPK14/GADD45A/MAP2K1/MAPK11/MDM2/BCL2L11/PTEN/PDPK1/MAPK13/CDKN1A	11
KEGG	hsa05010	Alzheimer disease	25/354	384/8135	0.02803	0.184	0.1571	TUBB6/FRAT1/KIF5B/CDK5R1/FRAT2/TUBA1C/TUBA1B/PSEN1/FADD/TNF/NDUFV1/MAP2K1/DDIT3/TUBA4A/TUBB3/EIF2S1/TNFRSF1A/LPL/APH1B/TUBB/TUBA1A/TUBA8/APAF1/TUBB4B/ATG101	25
KEGG	hsa05020	Prion disease	19/354	273/8135	0.0289	0.1857	0.1586	TUBB6/MAPK14/KIF5B/TUBA1C/TUBA1B/TNF/NDUFV1/DDIT3/TUBA4A/TUBB3/EIF2S1/MAPK11/C5/TUBB/TUBA1A/MAPK13/TUBA8/APAF1/TUBB4B	19
KEGG	hsa04920	Adipocytokine signaling pathway	7/354	69/8135	0.02971	0.1869	0.1596	ACSL1/ACSL3/TNFRSF1B/TNF/NFKBIE/TNFRSF1A/PPARA	7
KEGG	hsa04060	Cytokine-cytokine receptor interaction	20/354	295/8135	0.03235	0.1994	0.1702	CSF1R/IFNGR1/TNFRSF1B/IL1R2/TNF/PF4V1/TNFSF4/RELT/IL11RA/IL10RA/IL17B/TNFRSF1A/TNFSF14/CCR2/GH2/CLCF1/CCL2/LTB/OSMR/CCL13	20
KEGG	hsa05135	Yersinia infection	11/354	137/8135	0.03618	0.214	0.1827	MAPK14/IRAK4/NFATC3/NLRC4/TNF/MAP2K1/MAPK11/VAV3/MAPK13/CCL2/PIP5K1C	11
KEGG	hsa05134	Legionellosis	6/354	57/8135	0.03653	0.214	0.1827	ITGAM/NLRC4/TNF/NAIP/CR1/APAF1	6
KEGG	hsa04620	Toll-like receptor signaling pathway	9/354	104/8135	0.03684	0.214	0.1827	MAPK14/IRAK4/FADD/TOLLIP/TNF/MAP2K1/MAPK11/IKBKE/MAPK13	9
KEGG	hsa04218	Cellular senescence	12/354	156/8135	0.03914	0.223	0.1904	FOXO1/MAPK14/NFATC3/ZFP36L1/MYC/GADD45A/MAP2K1/MAPK11/MDM2/PTEN/MAPK13/CDKN1A	12
KEGG	hsa00061	Fatty acid biosynthesis	3/354	18/8135	0.04103	0.2295	0.1959	ACSL1/ACSL3/HSD17B8	3
KEGG	hsa04658	Th1 and Th2 cell differentiation	8/354	92/8135	0.04641	0.2503	0.2137	IFNGR1/MAPK14/NFATC3/NFKBIE/MAPK11/RUNX3/MAPK13/MAML3	8
KEGG	hsa05222	Small cell lung cancer	8/354	92/8135	0.04641	0.2503	0.2137	MYC/GADD45A/TRAF4/LAMA5/PTEN/CKS1B/APAF1/CDKN1A	8
KEGG	hsa04215	Apoptosis - multiple species	4/354	32/8135	0.04852	0.2571	0.2195	FADD/TNFRSF1A/BCL2L11/APAF1	4
KEGG	hsa04380	Osteoclast differentiation	10/354	128/8135	0.05196	0.2705	0.231	CSF1R/IFNGR1/MAPK14/OSCAR/MAP3K14/TNF/MAP2K1/MAPK11/TNFRSF1A/MAPK13	10
KEGG	hsa03410	Base excision repair	4/354	33/8135	0.0534	0.2733	0.2334	POLD2/TDG/LIG1/MBD4	4
KEGG	hsa04621	NOD-like receptor signaling pathway	13/354	184/8135	0.05772	0.2859	0.2441	MAPK14/IRAK4/FADD/NLRC4/TNF/RNASEL/MAPK11/NAIP/IKBKE/TRPM2/MAPK13/CCL2/NOD1	13
KEGG	hsa04670	Leukocyte transendothelial migration	9/354	114/8135	0.05993	0.2859	0.2441	EZR/MAPK14/ITGAM/ITGAL/MAPK11/VAV3/OCLN/MAPK13/PRKCA	9
KEGG	hsa04070	Phosphatidylinositol signaling system	8/354	97/8135	0.05997	0.2859	0.2441	PI4KA/MTMR4/ITPKB/ITPKC/MTMR3/PTEN/PRKCA/PIP5K1C	8
KEGG	hsa05215	Prostate cancer	8/354	97/8135	0.05997	0.2859	0.2441	FOXO1/TCF7L2/IL1R2/MAP2K1/MDM2/PTEN/PDPK1/CDKN1A	8
KEGG	hsa05168	Herpes simplex virus 1 infection	29/354	495/8135	0.06131	0.2859	0.2441	IFNGR1/IRAK4/POU2F2/FADD/SRPK1/ZNF10/ZNF713/ZNF461/TNF/ZNF93/ZNF671/RNASEL/ZNF189/ZNF425/EIF2S1/ZNF783/TNFRSF1A/TNFSF14/IKBKE/C5/ZFP69/ZNF354A/ZNF610/CCL2/APAF1/ZNF684/ZNF680/ZNF557/ZNF419	29
KEGG	hsa04728	Dopaminergic synapse	10/354	132/8135	0.06153	0.2859	0.2441	MAPK14/KIF5B/ARRB1/PPP2R1B/MAPK11/CAMK2G/MAPK13/GNG10/PRKCA/CLOCK	10
KEGG	hsa04530	Tight junction	12/354	169/8135	0.06455	0.2954	0.2522	EZR/TUBA1C/TUBA1B/CD1A/SLC9A3R1/PPP2R1B/TUBA4A/RDX/RAB8B/TUBA1A/OCLN/TUBA8	12
KEGG	hsa05163	Human cytomegalovirus infection	15/354	225/8135	0.06583	0.2967	0.2534	MAPK14/NFATC3/MYC/FADD/TNF/MAP2K1/MAPK11/MDM2/IL10RA/TNFRSF1A/MAPK13/CCL2/GNG10/PRKCA/CDKN1A	15
KEGG	hsa04150	mTOR signaling pathway	11/354	156/8135	0.0776	0.343	0.2929	ATP6V1C1/TNF/MAP2K1/ATP6V1B2/GRB10/TNFRSF1A/PTEN/PDPK1/ATP6V1E1/ATP6V1A/PRKCA	11
KEGG	hsa05210	Colorectal cancer	7/354	86/8135	0.07995	0.343	0.2929	TCF7L2/MYC/GADD45A/MAP2K1/RALB/BCL2L11/CDKN1A	7
KEGG	hsa05167	Kaposi sarcoma-associated herpesvirus infection	13/354	194/8135	0.08029	0.343	0.2929	IFNGR1/MAPK14/NFATC3/TCF7L2/MYC/FADD/MAP2K1/MAPK11/TNFRSF1A/IKBKE/MAPK13/GNG10/CDKN1A	13
KEGG	hsa04919	Thyroid hormone signaling pathway	9/354	121/8135	0.08065	0.343	0.2929	FOXO1/ATP1B1/MYC/MAP2K1/MDM2/PDPK1/NCOA1/PRKCA/MED24	9
KEGG	hsa04064	NF-kappa B signaling pathway	8/354	104/8135	0.08278	0.3472	0.2965	IRAK4/GADD45A/MAP3K14/TNF/TNFRSF1A/TNFSF14/LTB/CCL13	8
KEGG	hsa04928	Parathyroid hormone synthesis, secretion and action	8/354	106/8135	0.09012	0.3722	0.3178	ARRB1/SLC9A3R1/PLD1/MAP2K1/KL/PRKCA/NR4A2/CDKN1A	8
KEGG	hsa05218	Melanoma	6/354	72/8135	0.09243	0.3722	0.3178	GADD45A/FGF8/MAP2K1/MDM2/PTEN/CDKN1A	6
KEGG	hsa05223	Non-small cell lung cancer	6/354	72/8135	0.09243	0.3722	0.3178	KIF5B/GADD45A/MAP2K1/PDPK1/PRKCA/CDKN1A	6
KEGG	hsa04110	Cell cycle	9/354	126/8135	0.09781	0.3837	0.3277	CDKN1C/MYC/GADD45A/ORC2/CDC7/MDM2/MCM7/STAG1/CDKN1A	9
KEGG	hsa04931	Insulin resistance	8/354	108/8135	0.09783	0.3837	0.3277	FOXO1/TNF/PYGB/TNFRSF1A/PPP1R3D/PPARA/PTEN/PDPK1	8
KEGG	hsa04216	Ferroptosis	4/354	41/8135	0.1013	0.3844	0.3282	ACSL1/ACSL3/HMOX1/FTH1	4
KEGG	hsa05219	Bladder cancer	4/354	41/8135	0.1013	0.3844	0.3282	MYC/MAP2K1/MDM2/CDKN1A	4
KEGG	hsa04066	HIF-1 signaling pathway	8/354	109/8135	0.1018	0.3844	0.3282	IFNGR1/ARNT/ENO3/MAP2K1/HMOX1/CAMK2G/PRKCA/CDKN1A	8
KEGG	hsa05224	Breast cancer	10/354	147/8135	0.1072	0.3949	0.3372	FRAT1/FRAT2/TCF7L2/MYC/GADD45A/FGF8/MAP2K1/PTEN/NCOA1/CDKN1A	10
KEGG	hsa03320	PPAR signaling pathway	6/354	75/8135	0.1072	0.3949	0.3372	ACSL1/GK/ACSL3/PPARA/LPL/PDPK1	6
KEGG	hsa04912	GnRH signaling pathway	7/354	93/8135	0.1097	0.3993	0.341	MAPK14/PLD1/MAP2K1/MAPK11/CAMK2G/MAPK13/PRKCA	7
KEGG	hsa05220	Chronic myeloid leukemia	6/354	76/8135	0.1124	0.4007	0.3422	MYC/GADD45A/MAP2K1/MDM2/CBL/CDKN1A	6
KEGG	hsa04370	VEGF signaling pathway	5/354	59/8135	0.1128	0.4007	0.3422	MAPK14/MAP2K1/MAPK11/MAPK13/PRKCA	5
KEGG	hsa05225	Hepatocellular carcinoma	11/354	168/8135	0.1149	0.4036	0.3446	FRAT1/FRAT2/TCF7L2/MYC/GADD45A/MAP2K1/SMARCC1/HMOX1/PTEN/PRKCA/CDKN1A	11
KEGG	hsa05012	Parkinson disease	16/354	266/8135	0.1179	0.4092	0.3494	TUBB6/KIF5B/TUBA1C/TUBA1B/NDUFV1/DDIT3/TUBA4A/TUBB3/EIF2S1/CAMK2G/TUBB/TUBA1A/TUBA8/APAF1/TUBB4B/LRRK2	16
KEGG	hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	2/354	14/8135	0.1218	0.418	0.3569	B4GALT4/CHST2	2
KEGG	hsa04721	Synaptic vesicle cycle	6/354	78/8135	0.1232	0.418	0.3569	ATP6V1C1/ATP6V1B2/ATP6V0A4/ATP6V0E2/ATP6V1E1/ATP6V1A	6
KEGG	hsa04666	Fc gamma R-mediated phagocytosis	7/354	97/8135	0.1291	0.431	0.3681	PLD1/MAP2K1/WASF1/VAV3/MARCKSL1/PRKCA/PIP5K1C	7
KEGG	hsa03022	Basal transcription factors	4/354	45/8135	0.1307	0.431	0.3681	TAF8/GTF2A2/GTF2H1/GTF2E2	4
KEGG	hsa05170	Human immunodeficiency virus 1 infection	13/354	212/8135	0.1335	0.431	0.3681	MAPK14/IRAK4/NFATC3/FADD/TNFRSF1B/TNF/MAP2K1/MAPK11/CUL4B/TNFRSF1A/MAPK13/GNG10/PRKCA	13
KEGG	hsa04750	Inflammatory mediator regulation of TRP channels	7/354	98/8135	0.1342	0.431	0.3681	MAPK14/MAPK11/CAMK2G/PRKCH/MAPK13/NTRK1/PRKCA	7
KEGG	hsa04925	Aldosterone synthesis and secretion	7/354	98/8135	0.1342	0.431	0.3681	ATP1B1/CAMK1D/LDLR/CAMK2G/PRKCA/DAGLA/NR4A2	7
KEGG	hsa00604	Glycosphingolipid biosynthesis - ganglio series	2/354	15/8135	0.1367	0.4335	0.3702	ST3GAL5/ST6GALNAC3	2
KEGG	hsa04932	Non-alcoholic fatty liver disease	10/354	155/8135	0.1378	0.4335	0.3702	MAPK14/TNF/NDUFV1/DDIT3/EIF2S1/MAPK11/TNFRSF1A/PPARA/BCL2L11/MAPK13	10
KEGG	hsa04640	Hematopoietic cell lineage	7/354	99/8135	0.1394	0.4339	0.3705	CSF1R/ITGAM/CD1A/IL1R2/TNF/IL11RA/CR1	7
KEGG	hsa04933	AGE-RAGE signaling pathway in diabetic complications	7/354	100/8135	0.1446	0.4427	0.3781	FOXO1/MAPK14/TNF/MAPK11/MAPK13/CCL2/PRKCA	7
KEGG	hsa04146	Peroxisome	6/354	82/8135	0.1461	0.4427	0.3781	ACSL1/IDH1/ACSL3/PEX1/PEX6/ABCD3	6
KEGG	hsa03420	Nucleotide excision repair	4/354	47/8135	0.1466	0.4427	0.3781	POLD2/CUL4B/GTF2H1/LIG1	4
KEGG	hsa00520	Amino sugar and nucleotide sugar metabolism	4/354	49/8135	0.1632	0.4804	0.4102	GALE/FPGT/UGP2/CYB5R4	4
KEGG	hsa01232	Nucleotide metabolism	6/354	85/8135	0.1645	0.4804	0.4102	AMPD2/NUDT16/ADA/LACC1/AMPD3/NT5C2	6
KEGG	hsa04012	ErbB signaling pathway	6/354	85/8135	0.1645	0.4804	0.4102	MYC/MAP2K1/CBL/CAMK2G/PRKCA/CDKN1A	6
KEGG	hsa05221	Acute myeloid leukemia	5/354	67/8135	0.166	0.4804	0.4102	CSF1R/TCF7L2/MYC/ITGAM/MAP2K1	5
KEGG	hsa05166	Human T-cell leukemia virus 1 infection	13/354	222/8135	0.1699	0.4804	0.4102	NFATC3/MYC/MAP3K14/IL1R2/TNF/MAP2K1/TLN1/ITGAL/TNFRSF1A/PTEN/SRF/TCF3/CDKN1A	13
KEGG	hsa04979	Cholesterol metabolism	4/354	50/8135	0.1717	0.4804	0.4102	LPA/LDLR/MYLIP/LPL	4
KEGG	hsa05144	Malaria	4/354	50/8135	0.1717	0.4804	0.4102	TNF/ITGAL/CR1/CCL2	4
KEGG	hsa04130	SNARE interactions in vesicular transport	3/354	33/8135	0.1718	0.4804	0.4102	STX7/VAMP4/GOSR1	3
KEGG	hsa05230	Central carbon metabolism in cancer	5/354	70/8135	0.1881	0.5196	0.4437	IDH1/MYC/MAP2K1/PTEN/NTRK1	5
KEGG	hsa00600	Sphingolipid metabolism	4/354	52/8135	0.1893	0.5196	0.4437	SGPL1/SGMS2/CERS6/SPTLC1	4
KEGG	hsa01210	2-Oxocarboxylic acid metabolism	2/354	19/8135	0.1993	0.5408	0.4618	IDH1/BCAT1	2
KEGG	hsa00500	Starch and sucrose metabolism	3/354	36/8135	0.2052	0.5408	0.4618	GYG1/PYGB/UGP2	3
KEGG	hsa03030	DNA replication	3/354	36/8135	0.2052	0.5408	0.4618	POLD2/MCM7/LIG1	3
KEGG	hsa05171	Coronavirus disease - COVID-19	13/354	232/8135	0.2107	0.5408	0.4618	CFD/MAPK14/IRAK4/TNF/MAPK11/RPL12/TNFRSF1A/IKBKE/C5/RPS4Y1/MAPK13/CCL2/PRKCA	13
KEGG	hsa04141	Protein processing in endoplasmic reticulum	10/354	171/8135	0.211	0.5408	0.4618	MAN1A2/LMAN1/DNAJC1/DDIT3/SEC24A/AMFR/EIF2S1/PREB/SEC31A/MBTPS2	10
KEGG	hsa01524	Platinum drug resistance	5/354	73/8135	0.2112	0.5408	0.4618	FADD/MDM2/PDPK1/APAF1/CDKN1A	5
KEGG	hsa04115	p53 signaling pathway	5/354	73/8135	0.2112	0.5408	0.4618	GADD45A/MDM2/PTEN/APAF1/CDKN1A	5
KEGG	hsa00100	Steroid biosynthesis	2/354	20/8135	0.2155	0.5408	0.4618	SQLE/LBR	2
KEGG	hsa01250	Biosynthesis of nucleotide sugars	3/354	37/8135	0.2167	0.5408	0.4618	GALE/FPGT/UGP2	3
KEGG	hsa04960	Aldosterone-regulated sodium reabsorption	3/354	37/8135	0.2167	0.5408	0.4618	ATP1B1/PDPK1/PRKCA	3
KEGG	hsa05143	African trypanosomiasis	3/354	37/8135	0.2167	0.5408	0.4618	THOP1/TNF/PRKCA	3
KEGG	hsa04921	Oxytocin signaling pathway	9/354	154/8135	0.2276	0.5635	0.4812	NFATC3/CAMK1D/KCNJ2/MAP2K1/RGS2/CAMK2G/TRPM2/PRKCA/CDKN1A	9
KEGG	hsa04971	Gastric acid secretion	5/354	76/8135	0.2352	0.5728	0.4892	EZR/ATP1B1/KCNJ2/CAMK2G/PRKCA	5
KEGG	hsa05212	Pancreatic cancer	5/354	76/8135	0.2352	0.5728	0.4892	GADD45A/PLD1/MAP2K1/RALB/CDKN1A	5
KEGG	hsa05150	Staphylococcus aureus infection	6/354	96/8135	0.2393	0.5782	0.4937	FPR2/CFD/ITGAM/ITGAL/FPR1/C5	6
KEGG	hsa00340	Histidine metabolism	2/354	22/8135	0.2481	0.5837	0.4984	AMDHD1/ALDH2	2
KEGG	hsa01522	Endocrine resistance	6/354	98/8135	0.2539	0.5837	0.4984	MAPK14/MAP2K1/MAPK11/MDM2/MAPK13/CDKN1A	6
KEGG	hsa05231	Choline metabolism in cancer	6/354	98/8135	0.2539	0.5837	0.4984	PLD1/MAP2K1/WASF1/PDPK1/PRKCA/PIP5K1C	6
KEGG	hsa04330	Notch signaling pathway	4/354	59/8135	0.2544	0.5837	0.4984	PSEN1/LFNG/APH1B/MAML3	4
KEGG	hsa05016	Huntington disease	16/354	306/8135	0.2583	0.5837	0.4984	TUBB6/KIF5B/TUBA1C/TUBA1B/HIP1/NDUFV1/TUBA4A/TUBB3/DCTN4/TUBB/TUBA1A/TFAM/TUBA8/APAF1/TUBB4B/ATG101	16
KEGG	hsa05418	Fluid shear stress and atherosclerosis	8/354	139/8135	0.2585	0.5837	0.4984	MAPK14/IL1R2/TNF/HMOX1/MAPK11/TNFRSF1A/MAPK13/CCL2	8
KEGG	hsa03018	RNA degradation	5/354	79/8135	0.2599	0.5837	0.4984	BTG2/ENO3/CNOT7/NUDT16/XRN1	5
KEGG	hsa04935	Growth hormone synthesis, secretion and action	7/354	119/8135	0.2605	0.5837	0.4984	MAPK14/MAP2K1/SSTR1/MAPK11/GH2/MAPK13/PRKCA	7
KEGG	hsa00515	Mannose type O-glycan biosynthesis	2/354	23/8135	0.2645	0.5837	0.4984	CHST10/POMT1	2
KEGG	hsa03430	Mismatch repair	2/354	23/8135	0.2645	0.5837	0.4984	POLD2/LIG1	2
KEGG	hsa04964	Proximal tubule bicarbonate reclamation	2/354	23/8135	0.2645	0.5837	0.4984	ATP1B1/SLC38A3	2
KEGG	hsa05208	Chemical carcinogenesis - reactive oxygen species	12/354	223/8135	0.2648	0.5837	0.4984	MAPK14/ARNT/PLD1/MAP3K14/NDUFV1/MAP2K1/HMOX1/MAPK11/PTEN/PDPK1/MAPK13/SLC26A1	12
KEGG	hsa00561	Glycerolipid metabolism	4/354	61/8135	0.2738	0.5992	0.5117	GK/MGLL/ALDH2/LPL	4
KEGG	hsa04550	Signaling pathways regulating pluripotency of stem cells	8/354	143/8135	0.2836	0.6122	0.5228	SMAD1/MAPK14/MYC/MAP2K1/MAPK11/MAPK13/ZFHX3/TCF3	8
KEGG	hsa05146	Amoebiasis	6/354	102/8135	0.2838	0.6122	0.5228	ITGAM/CD1A/IL1R2/TNF/LAMA5/PRKCA	6
KEGG	hsa00071	Fatty acid degradation	3/354	43/8135	0.2875	0.6159	0.5259	ACSL1/ACSL3/ALDH2	3
KEGG	hsa04310	Wnt signaling pathway	9/354	167/8135	0.303	0.6444	0.5503	TBL1Y/FRAT1/NFATC3/FRAT2/TCF7L2/PSEN1/MYC/CAMK2G/PRKCA	9
KEGG	hsa00563	Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	2/354	26/8135	0.3135	0.6621	0.5654	PIGZ/PIGB	2
KEGG	hsa04723	Retrograde endocannabinoid signaling	8/354	148/8135	0.3158	0.6624	0.5657	MAPK14/NDUFV1/MGLL/MAPK11/MAPK13/GNG10/PRKCA/DAGLA	8
KEGG	hsa05226	Gastric cancer	8/354	149/8135	0.3224	0.6678	0.5702	FRAT1/FRAT2/TCF7L2/MYC/GADD45A/FGF8/MAP2K1/CDKN1A	8
KEGG	hsa00230	Purine metabolism	7/354	128/8135	0.3228	0.6678	0.5702	AMPD2/NUDT16/ADA/GART/LACC1/AMPD3/NT5C2	7
KEGG	hsa04261	Adrenergic signaling in cardiomyocytes	8/354	150/8135	0.3289	0.6687	0.571	MAPK14/ATP1B1/KCNE1/PPP2R1B/MAPK11/CAMK2G/MAPK13/PRKCA	8
KEGG	hsa04659	Th17 cell differentiation	6/354	108/8135	0.3299	0.6687	0.571	IFNGR1/MAPK14/NFATC3/NFKBIE/MAPK11/MAPK13	6
KEGG	hsa04926	Relaxin signaling pathway	7/354	129/8135	0.3299	0.6687	0.571	MAPK14/ARRB1/MAP2K1/MAPK11/MAPK13/GNG10/PRKCA	7
KEGG	hsa00620	Pyruvate metabolism	3/354	47/8135	0.3358	0.6761	0.5773	DLD/ME2/ALDH2	3
KEGG	hsa00280	Valine, leucine and isoleucine degradation	3/354	48/8135	0.3479	0.6957	0.5941	DLD/ALDH2/BCAT1	3
KEGG	hsa04810	Regulation of actin cytoskeleton	11/354	218/8135	0.3506	0.6965	0.5948	EZR/SSH1/ITGAM/FGF8/MAP2K1/TMSB4Y/ITGAL/RDX/WASF1/VAV3/PIP5K1C	11
KEGG	hsa00565	Ether lipid metabolism	3/354	49/8135	0.3599	0.7029	0.6002	PLD1/PAFAH1B1/PLD4	3
KEGG	hsa04672	Intestinal immune network for IgA production	3/354	49/8135	0.3599	0.7029	0.6002	MAP3K14/AICDA/ICOSLG	3
KEGG	hsa04917	Prolactin signaling pathway	4/354	70/8135	0.3633	0.7029	0.6002	MAPK14/MAP2K1/MAPK11/MAPK13	4
KEGG	hsa00190	Oxidative phosphorylation	7/354	134/8135	0.3657	0.7029	0.6002	ATP6V1C1/NDUFV1/ATP6V1B2/ATP6V0A4/ATP6V0E2/ATP6V1E1/ATP6V1A	7
KEGG	hsa04270	Vascular smooth muscle contraction	7/354	134/8135	0.3657	0.7029	0.6002	ADORA2B/MAP2K1/PTGIR/KCNU1/PRKCH/AVP/PRKCA	7
KEGG	hsa04080	Neuroactive ligand-receptor interaction	17/354	353/8135	0.3679	0.7029	0.6002	FPR2/ADORA2B/PTGFR/F2RL3/PPY/ADORA3/PTGIR/FPR1/SSTR1/GPR83/GPR35/C5/ADORA1/GH2/AVP/HTR1B/SSTR4	17
KEGG	hsa04151	PI3K-Akt signaling pathway	17/354	354/8135	0.3724	0.7029	0.6002	CSF1R/MYC/PPP2R1B/FGF8/MAP2K1/LAMA5/MDM2/PHLPP2/BCL2L11/GH2/PTEN/PDPK1/NTRK1/GNG10/PRKCA/OSMR/CDKN1A	17
KEGG	hsa00020	Citrate cycle (TCA cycle)	2/354	30/8135	0.3777	0.7029	0.6002	DLD/IDH1	2
KEGG	hsa00053	Ascorbate and aldarate metabolism	2/354	30/8135	0.3777	0.7029	0.6002	KL/ALDH2	2
KEGG	hsa01523	Antifolate resistance	2/354	30/8135	0.3777	0.7029	0.6002	TNF/GART	2
KEGG	hsa00270	Cysteine and methionine metabolism	3/354	51/8135	0.3839	0.7029	0.6002	LACC1/PHGDH/BCAT1	3
KEGG	hsa05131	Shigellosis	12/354	247/8135	0.3895	0.7029	0.6002	FOXO1/MAPK14/NLRC4/TNF/TLN1/MAPK11/WASF1/MDM2/NAIP/TNFRSF1A/MAPK13/NOD1	12
KEGG	hsa05415	Diabetic cardiomyopathy	10/354	203/8135	0.3898	0.7029	0.6002	MAPK14/NDUFV1/MPC1/GSR/MAPK11/PPARA/PTEN/CAMK2G/MAPK13/PRKCA	10
KEGG	hsa00052	Galactose metabolism	2/354	31/8135	0.3933	0.7029	0.6002	GALE/UGP2	2
KEGG	hsa00410	beta-Alanine metabolism	2/354	31/8135	0.3933	0.7029	0.6002	DPYD/ALDH2	2
KEGG	hsa04710	Circadian rhythm	2/354	31/8135	0.3933	0.7029	0.6002	BHLHE40/CLOCK	2
KEGG	hsa05310	Asthma	2/354	31/8135	0.3933	0.7029	0.6002	PRG2/TNF	2
KEGG	hsa05203	Viral carcinogenesis	10/354	204/8135	0.3957	0.703	0.6003	DDX3X/CHD4/HDAC5/GTF2A2/MDM2/GTF2H1/GTF2E2/SRF/EGR3/CDKN1A	10
KEGG	hsa04961	Endocrine and other factor-regulated calcium reabsorption	3/354	53/8135	0.4077	0.72	0.6148	ATP1B1/KL/PRKCA	3
KEGG	hsa01230	Biosynthesis of amino acids	4/354	75/8135	0.4131	0.7254	0.6194	IDH1/ENO3/PHGDH/BCAT1	4
KEGG	hsa04140	Autophagy - animal	7/354	141/8135	0.4161	0.7263	0.6203	MAP2K1/MTMR4/MTMR3/EIF2S1/PTEN/PDPK1/ATG101	7
KEGG	hsa00040	Pentose and glucuronate interconversions	2/354	34/8135	0.4392	0.7555	0.6451	KL/UGP2	2
KEGG	hsa04022	cGMP-PKG signaling pathway	8/354	167/8135	0.4422	0.7555	0.6451	ATP1B1/NFATC3/MAP2K1/ADORA3/KCNU1/RGS2/ADORA1/SRF	8
KEGG	hsa04340	Hedgehog signaling pathway	3/354	56/8135	0.4428	0.7555	0.6451	CSNK1G1/ARRB1/EFCAB7	3
KEGG	hsa04923	Regulation of lipolysis in adipocytes	3/354	56/8135	0.4428	0.7555	0.6451	MGLL/ADORA1/ABHD5	3
KEGG	hsa01521	EGFR tyrosine kinase inhibitor resistance	4/354	79/8135	0.4524	0.7637	0.6521	MAP2K1/BCL2L11/PTEN/PRKCA	4
KEGG	hsa01212	Fatty acid metabolism	3/354	57/8135	0.4543	0.7637	0.6521	ACSL1/ACSL3/HSD17B8	3
KEGG	hsa04611	Platelet activation	6/354	124/8135	0.4552	0.7637	0.6521	MAPK14/F2RL3/TLN1/PTGIR/MAPK11/MAPK13	6
KEGG	hsa04072	Phospholipase D signaling pathway	7/354	148/8135	0.4662	0.7778	0.6642	PTGFR/PLD1/MAP2K1/RALB/AVP/PRKCA/PIP5K1C	7
KEGG	hsa04662	B cell receptor signaling pathway	4/354	82/8135	0.4813	0.7986	0.682	NFATC3/MAP2K1/NFKBIE/VAV3	4
KEGG	hsa04730	Long-term depression	3/354	60/8135	0.4883	0.8014	0.6843	PPP2R1B/MAP2K1/PRKCA	3
KEGG	hsa04978	Mineral absorption	3/354	60/8135	0.4883	0.8014	0.6843	ATP1B1/HMOX1/FTH1	3
KEGG	hsa05340	Primary immunodeficiency	2/354	38/8135	0.4973	0.8087	0.6906	AICDA/ADA	2
KEGG	hsa00140	Steroid hormone biosynthesis	3/354	61/8135	0.4993	0.8087	0.6906	HSD17B8/CYP19A1/STS	3
KEGG	hsa04922	Glucagon signaling pathway	5/354	107/8135	0.5008	0.8087	0.6906	FOXO1/SIK1/PYGB/PPARA/CAMK2G	5
KEGG	hsa04114	Oocyte meiosis	6/354	131/8135	0.5086	0.8127	0.694	MAPK14/PPP2R1B/MAP2K1/MAPK11/CAMK2G/MAPK13	6
KEGG	hsa04650	Natural killer cell mediated cytotoxicity	6/354	131/8135	0.5086	0.8127	0.694	IFNGR1/TNF/MAP2K1/ITGAL/VAV3/PRKCA	6
KEGG	hsa04510	Focal adhesion	9/354	201/8135	0.514	0.817	0.6977	FLNC/MAP2K1/TLN1/LAMA5/VAV3/PTEN/PDPK1/PRKCA/PIP5K1C	9
KEGG	hsa04911	Insulin secretion	4/354	86/8135	0.5189	0.8197	0.7	ATP1B1/KCNU1/CAMK2G/PRKCA	4
KEGG	hsa05217	Basal cell carcinoma	3/354	63/8135	0.5212	0.8197	0.7	TCF7L2/GADD45A/CDKN1A	3
KEGG	hsa00260	Glycine, serine and threonine metabolism	2/354	40/8135	0.5248	0.8212	0.7013	DLD/PHGDH	2
KEGG	hsa00120	Primary bile acid biosynthesis	1/354	17/8135	0.531	0.8237	0.7034	CH25H	1
KEGG	hsa04929	GnRH secretion	3/354	64/8135	0.5319	0.8237	0.7034	ARRB1/MAP2K1/PRKCA	3
KEGG	hsa04144	Endocytosis	11/354	251/8135	0.535	0.8243	0.7039	KIF5B/IGF2R/RAB11FIP4/ARRB1/PLD1/LDLR/MDM2/RAB31/CBL/VPS37A/PIP5K1C	11
KEGG	hsa04217	Necroptosis	7/354	159/8135	0.5426	0.8249	0.7044	IFNGR1/FADD/TNF/PYGB/TNFRSF1A/CAMK2G/FTH1	7
KEGG	hsa04727	GABAergic synapse	4/354	89/8135	0.5462	0.8249	0.7044	SLC38A2/SLC38A3/GNG10/PRKCA	4
KEGG	hsa04725	Cholinergic synapse	5/354	113/8135	0.5496	0.8249	0.7044	KCNJ2/MAP2K1/CAMK2G/GNG10/PRKCA	5
KEGG	hsa00380	Tryptophan metabolism	2/354	42/8135	0.5514	0.8249	0.7044	DLD/ALDH2	2
KEGG	hsa04910	Insulin signaling pathway	6/354	137/8135	0.5529	0.8249	0.7044	FOXO1/MAP2K1/PYGB/PPP1R3D/CBL/PDPK1	6
KEGG	hsa04724	Glutamatergic synapse	5/354	114/8135	0.5576	0.8249	0.7044	SLC38A2/PLD1/SLC38A3/GNG10/PRKCA	5
KEGG	hsa04630	JAK-STAT signaling pathway	7/354	162/8135	0.5626	0.8249	0.7044	IFNGR1/MYC/IL11RA/IL10RA/GH2/OSMR/CDKN1A	7
KEGG	hsa00010	Glycolysis / Gluconeogenesis	3/354	67/8135	0.5632	0.8249	0.7044	DLD/ENO3/ALDH2	3
KEGG	hsa04720	Long-term potentiation	3/354	67/8135	0.5632	0.8249	0.7044	MAP2K1/CAMK2G/PRKCA	3
KEGG	hsa05032	Morphine addiction	4/354	91/8135	0.5639	0.8249	0.7044	ARRB1/ADORA1/GNG10/PRKCA	4
KEGG	hsa01200	Carbon metabolism	5/354	115/8135	0.5654	0.8249	0.7044	DLD/IDH1/ENO3/ME2/PHGDH	5
KEGG	hsa00531	Glycosaminoglycan degradation	1/354	19/8135	0.571	0.8285	0.7075	HYAL4	1
KEGG	hsa04962	Vasopressin-regulated water reabsorption	2/354	44/8135	0.5768	0.8285	0.7075	DCTN4/AVP	2
KEGG	hsa05207	Chemical carcinogenesis - receptor activation	9/354	212/8135	0.5792	0.8285	0.7075	ARRB1/MYC/ARNT/FGF8/MAP2K1/IKBKE/PPARA/KPNA1/PRKCA	9
KEGG	hsa04970	Salivary secretion	4/354	93/8135	0.5813	0.8285	0.7075	ATP1B1/BEST2/AQP5/PRKCA	4
KEGG	hsa05211	Renal cell carcinoma	3/354	69/8135	0.5833	0.8285	0.7075	ARNT/MAP2K1/CDKN1A	3
KEGG	hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	1/354	20/8135	0.5897	0.8285	0.7075	CSGALNACT2	1
KEGG	hsa00670	One carbon pool by folate	1/354	20/8135	0.5897	0.8285	0.7075	GART	1
KEGG	hsa04350	TGF-beta signaling pathway	4/354	94/8135	0.5898	0.8285	0.7075	SMAD1/MYC/TNF/PPP2R1B	4
KEGG	hsa04062	Chemokine signaling pathway	8/354	192/8135	0.6015	0.8386	0.7162	ARRB1/MAP2K1/PF4V1/VAV3/CCR2/CCL2/GNG10/CCL13	8
KEGG	hsa04020	Calcium signaling pathway	10/354	240/8135	0.6026	0.8386	0.7162	ADORA2B/CAMK1D/PTGFR/FGF8/ASPH/ITPKB/ITPKC/CAMK2G/NTRK1/PRKCA	10
KEGG	hsa00514	Other types of O-glycan biosynthesis	2/354	47/8135	0.613	0.8492	0.7252	LFNG/POMT1	2
KEGG	hsa04024	cAMP signaling pathway	9/354	221/8135	0.6295	0.8681	0.7413	ATP1B1/PLD1/MAP2K1/SSTR1/VAV3/PPARA/ADORA1/CAMK2G/HTR1B	9
KEGG	hsa04918	Thyroid hormone synthesis	3/354	75/8135	0.6401	0.8721	0.7447	ATP1B1/GSR/PRKCA	3
KEGG	hsa03060	Protein export	1/354	23/8135	0.6411	0.8721	0.7447	SRP54	1
KEGG	hsa04614	Renin-angiotensin system	1/354	23/8135	0.6411	0.8721	0.7447	THOP1	1
KEGG	hsa04916	Melanogenesis	4/354	101/8135	0.6466	0.8721	0.7447	TCF7L2/MAP2K1/CAMK2G/PRKCA	4
KEGG	hsa00510	N-Glycan biosynthesis	2/354	50/8135	0.6468	0.8721	0.7447	MAN1A2/ALG6	2
KEGG	hsa04914	Progesterone-mediated oocyte maturation	4/354	102/8135	0.6543	0.8748	0.747	MAPK14/MAP2K1/MAPK11/MAPK13	4
KEGG	hsa00330	Arginine and proline metabolism	2/354	51/8135	0.6576	0.8748	0.747	ALDH2/CKM	2
KEGG	hsa04913	Ovarian steroidogenesis	2/354	51/8135	0.6576	0.8748	0.747	CYP19A1/LDLR	2
KEGG	hsa01240	Biosynthesis of cofactors	6/354	153/8135	0.6608	0.8753	0.7475	DLD/PPCDC/ALDH2/UGP2/PANK3/BCAT1	6
KEGG	hsa04934	Cushing syndrome	6/354	155/8135	0.6731	0.8877	0.7581	TCF7L2/ARNT/MAP2K1/LDLR/CAMK2G/CDKN1A	6
KEGG	hsa04714	Thermogenesis	9/354	232/8135	0.6863	0.8993	0.7679	ACSL1/MAPK14/ACSL3/NDUFV1/MGLL/SMARCC1/MAPK11/MAPK13/NDUFAF1	9
KEGG	hsa03460	Fanconi anemia pathway	2/354	54/8135	0.6882	0.8993	0.7679	POLI/RMI1	2
KEGG	hsa03013	Nucleocytoplasmic transport	4/354	108/8135	0.698	0.8993	0.7679	NXT1/NXT2/KPNA1/NUP62	4
KEGG	hsa00062	Fatty acid elongation	1/354	27/8135	0.6998	0.8993	0.7679	ACOT7	1
KEGG	hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	1/354	27/8135	0.6998	0.8993	0.7679	B4GALT4	1
KEGG	hsa01040	Biosynthesis of unsaturated fatty acids	1/354	27/8135	0.6998	0.8993	0.7679	ACOT7	1
KEGG	hsa00240	Pyrimidine metabolism	2/354	58/8135	0.7255	0.9245	0.7895	DPYD/NT5C2	2
KEGG	hsa00480	Glutathione metabolism	2/354	58/8135	0.7255	0.9245	0.7895	IDH1/GSR	2
KEGG	hsa05162	Measles	5/354	139/8135	0.7297	0.9259	0.7907	IRAK4/FADD/EIF2S1/IKBKE/APAF1	5
KEGG	hsa00630	Glyoxylate and dicarboxylate metabolism	1/354	30/8135	0.7374	0.9318	0.7957	DLD	1
KEGG	hsa04726	Serotonergic synapse	4/354	115/8135	0.7438	0.9359	0.7993	MAP2K1/GNG10/PRKCA/HTR1B	4
KEGG	hsa04211	Longevity regulating pathway	3/354	89/8135	0.7507	0.9369	0.8001	FOXO1/KL/ATG101	3
KEGG	hsa04976	Bile secretion	3/354	89/8135	0.7507	0.9369	0.8001	AQP9/ATP1B1/LDLR	3
KEGG	hsa00640	Propanoate metabolism	1/354	32/8135	0.7598	0.9405	0.8031	DLD	1
KEGG	hsa04136	Autophagy - other	1/354	32/8135	0.7598	0.9405	0.8031	ATG101	1
KEGG	hsa00310	Lysine degradation	2/354	63/8135	0.7668	0.9413	0.8038	DLD/ALDH2	2
KEGG	hsa03250	Viral life cycle - HIV-1	2/354	63/8135	0.7668	0.9413	0.8038	BICD1/ELL2	2
KEGG	hsa00051	Fructose and mannose metabolism	1/354	33/8135	0.7703	0.9419	0.8043	FPGT	1
KEGG	hsa05321	Inflammatory bowel disease	2/354	65/8135	0.7817	0.9451	0.807	IFNGR1/TNF	2
KEGG	hsa04014	Ras signaling pathway	8/354	232/8135	0.7982	0.9451	0.807	CSF1R/PLD1/FGF8/MAP2K1/RALB/NTRK1/GNG10/PRKCA	8
KEGG	hsa05206	MicroRNAs in cancer	11/354	310/8135	0.799	0.9451	0.807	EZR/MYC/HDAC5/MAP2K1/HMOX1/RDX/MDM2/BCL2L11/PTEN/PRKCA/CDKN1A	11
KEGG	hsa00512	Mucin type O-glycan biosynthesis	1/354	36/8135	0.7992	0.9451	0.807	ST6GALNAC3	1
KEGG	hsa00760	Nicotinate and nicotinamide metabolism	1/354	36/8135	0.7992	0.9451	0.807	NT5C2	1
KEGG	hsa03015	mRNA surveillance pathway	3/354	97/8135	0.8007	0.9451	0.807	PPP2R1B/NXT1/NXT2	3
KEGG	hsa04713	Circadian entrainment	3/354	97/8135	0.8007	0.9451	0.807	CAMK2G/GNG10/PRKCA	3
KEGG	hsa00564	Glycerophospholipid metabolism	3/354	98/8135	0.8063	0.9451	0.807	PLD1/CRLS1/PLD4	3
KEGG	hsa04924	Renin secretion	2/354	69/8135	0.8091	0.9451	0.807	KCNJ2/ADORA1	2
KEGG	hsa05031	Amphetamine addiction	2/354	69/8135	0.8091	0.9451	0.807	CAMK2G/PRKCA	2
KEGG	hsa05204	Chemical carcinogenesis - DNA adducts	2/354	69/8135	0.8091	0.9451	0.807	SULT1A2/SULT1A1	2
KEGG	hsa04360	Axon guidance	6/354	182/8135	0.8105	0.9451	0.807	NFATC3/SSH1/PLXNB2/CAMK2G/PDPK1/PRKCA	6
KEGG	hsa05330	Allograft rejection	1/354	38/8135	0.8163	0.9466	0.8084	TNF	1
KEGG	hsa04390	Hippo signaling pathway	5/354	157/8135	0.8199	0.9466	0.8084	SMAD1/TCF7L2/MYC/PPP2R1B/TP53BP2	5
KEGG	hsa04520	Adherens junction	2/354	71/8135	0.8216	0.9466	0.8084	TCF7L2/WASF1	2
KEGG	hsa00513	Various types of N-glycan biosynthesis	1/354	39/8135	0.8244	0.9466	0.8084	MAN1A2	1
KEGG	hsa04974	Protein digestion and absorption	3/354	103/8135	0.8324	0.9491	0.8105	ATP1B1/SLC38A2/SLC36A4	3
KEGG	hsa04142	Lysosome	4/354	132/8135	0.8328	0.9491	0.8105	IGF2R/LGMN/ATP6V0A4/HYAL4	4
KEGG	hsa03440	Homologous recombination	1/354	41/8135	0.8394	0.9527	0.8135	POLD2	1
KEGG	hsa05332	Graft-versus-host disease	1/354	42/8135	0.8464	0.9527	0.8135	TNF	1
KEGG	hsa00860	Porphyrin metabolism	1/354	43/8135	0.8531	0.9527	0.8135	HMOX1	1
KEGG	hsa04940	Type I diabetes mellitus	1/354	43/8135	0.8531	0.9527	0.8135	TNF	1
KEGG	hsa05100	Bacterial invasion of epithelial cells	2/354	77/8135	0.8548	0.9527	0.8135	WASF1/CBL	2
KEGG	hsa03008	Ribosome biogenesis in eukaryotes	3/354	109/8135	0.8597	0.9527	0.8135	NXT1/XRN1/NXT2	3
KEGG	hsa04612	Antigen processing and presentation	2/354	78/8135	0.8598	0.9527	0.8135	LGMN/TNF	2
KEGG	hsa04371	Apelin signaling pathway	4/354	139/8135	0.8612	0.9527	0.8135	HDAC5/MAP2K1/TFAM/GNG10	4
KEGG	hsa02010	ABC transporters	1/354	45/8135	0.8657	0.9542	0.8148	ABCD3	1
KEGG	hsa04930	Type II diabetes mellitus	1/354	46/8135	0.8716	0.9571	0.8174	TNF	1
KEGG	hsa04973	Carbohydrate digestion and absorption	1/354	47/8135	0.8772	0.9598	0.8197	ATP1B1	1
KEGG	hsa05030	Cocaine addiction	1/354	49/8135	0.8877	0.967	0.8258	CDK5R1	1
KEGG	hsa04742	Taste transduction	2/354	86/8135	0.8942	0.967	0.8258	SCN3A/HTR1B	2
KEGG	hsa04514	Cell adhesion molecules	4/354	149/8135	0.8945	0.967	0.8258	ITGAM/ITGAL/ICOSLG/OCLN	4
KEGG	hsa04260	Cardiac muscle contraction	2/354	87/8135	0.8979	0.967	0.8258	ATP1B1/ASPH	2
KEGG	hsa04152	AMPK signaling pathway	3/354	120/8135	0.8997	0.967	0.8258	FOXO1/PPP2R1B/PDPK1	3
KEGG	hsa05416	Viral myocarditis	1/354	60/8135	0.9314	0.9884	0.8441	ITGAL	1
KEGG	hsa04213	Longevity regulating pathway - multiple species	1/354	62/8135	0.9373	0.9884	0.8441	FOXO1	1
KEGG	hsa05322	Systemic lupus erythematosus	3/354	136/8135	0.9398	0.9884	0.8441	TNF/ELANE/C5	3
KEGG	hsa04623	Cytosolic DNA-sensing pathway	1/354	63/8135	0.94	0.9884	0.8441	IKBKE	1
KEGG	hsa04972	Pancreatic secretion	2/354	102/8135	0.9408	0.9884	0.8441	ATP1B1/PRKCA	2
KEGG	hsa04915	Estrogen signaling pathway	3/354	138/8135	0.9436	0.9884	0.8441	MAP2K1/FKBP5/NCOA1	3
KEGG	hsa04927	Cortisol synthesis and secretion	1/354	65/8135	0.9452	0.9884	0.8441	LDLR	1
KEGG	hsa04120	Ubiquitin mediated proteolysis	3/354	142/8135	0.9505	0.9884	0.8441	MDM2/CUL4B/CBL	3
KEGG	hsa00830	Retinol metabolism	1/354	68/8135	0.9521	0.9884	0.8441	CYP2S1	1
KEGG	hsa03040	Spliceosome	3/354	147/8135	0.9581	0.9884	0.8441	PRPF6/CRNKL1/SF3A3	3
KEGG	hsa04137	Mitophagy - animal	1/354	72/8135	0.96	0.9884	0.8441	RHOT1	1
KEGG	hsa05034	Alcoholism	4/354	187/8135	0.9658	0.9884	0.8441	ADORA2B/HDAC5/MAP2K1/GNG10	4
KEGG	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	1/354	77/8135	0.968	0.9884	0.8441	TCF7L2	1
KEGG	hsa00980	Metabolism of xenobiotics by cytochrome P450	1/354	78/8135	0.9694	0.9884	0.8441	CYP2S1	1
KEGG	hsa03010	Ribosome	3/354	158/8135	0.9711	0.9884	0.8441	RPL12/MRPL4/RPS4Y1	3
KEGG	hsa00983	Drug metabolism - other enzymes	1/354	80/8135	0.972	0.9884	0.8441	DPYD	1
KEGG	hsa04512	ECM-receptor interaction	1/354	88/8135	0.9805	0.9909	0.8461	LAMA5	1
KEGG	hsa05410	Hypertrophic cardiomyopathy	1/354	90/8135	0.9822	0.9909	0.8461	TNF	1
KEGG	hsa05414	Dilated cardiomyopathy	1/354	96/8135	0.9864	0.9909	0.8461	TNF	1
KEGG	hsa05017	Spinocerebellar ataxia	2/354	143/8135	0.9876	0.9909	0.8461	PRKCA/ATG101	2
KEGG	hsa04740	Olfactory transduction	4/354	440/8135	1	1	0.854	ARRB1/RGS2/CAMK2G/OR6A2	4