ONTOLOGY	ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	qvalue	geneID	Count
KEGG	hsa04612	Antigen processing and presentation	17/740	78/8135	0.0005179	0.07304	0.06721	HLA-B/HLA-A/CTSB/TAP1/CTSS/HSPA5/HLA-F/TAPBP/KIR3DL3/TAP2/HLA-DMB/HSP90AB1/CIITA/CD74/IFI30/B2M/HLA-DPA1	17
KEGG	hsa05169	Epstein-Barr virus infection	33/740	202/8135	0.0006238	0.07304	0.06721	HLA-B/ISG15/IRF9/MYC/STAT2/HLA-A/TAP1/OAS1/OAS2/CD44/STAT3/STAT1/HLA-F/CCND3/MAP2K6/CXCL10/RELA/TAPBP/ICAM1/TAP2/HLA-DMB/OAS3/B2M/NFKBIA/HLA-DPA1/CCND1/FADD/AKT3/RELB/GADD45A/NEDD4/NFKBIE/CDK2	33
KEGG	hsa05168	Herpes simplex virus 1 infection	66/740	495/8135	0.000837	0.07304	0.06721	ZNF91/ZNF429/HLA-B/SOCS3/IRF9/ZNF577/STAT2/ZNF567/ZNF93/HLA-A/TAP1/ZNF510/PPP1CB/OAS1/ZNF667/PML/OAS2/ZNF404/SRSF7/SRSF6/ZNF211/ZNF57/ZNF212/ZNF624/ZNF112/ZNF727/ITGA5/ZNF514/ZNF583/STAT1/ZNF569/HLA-F/ZNF778/RELA/TAPBP/IL1B/ZNF721/ZNF300/ZNF233/BCL2L1/ZNF19/TAP2/HLA-DMB/ZNF14/OAS3/ZNF534/CD74/B2M/NFKBIA/ZNF610/ZNF676/HLA-DPA1/ZNF248/FADD/CCL5/AKT3/ZNF841/ZNF81/ZNF559-ZNF177/ZNF813/DAXX/ZNF517/ZNF578/ZNF282/ZNF135/ZNF226	66
KEGG	hsa05171	Coronavirus disease - COVID-19	36/740	232/8135	0.0009617	0.07304	0.06721	MX1/RPS3A/RPL10A/RPLP0/C9/ISG15/IL6ST/IRF9/STAT2/C7/TLR8/RPS18/FOS/OAS1/OAS2/TLR4/RPL24/RPS6/STAT3/RPL11/STAT1/CXCL10/RELA/RPL36AL/IL1B/RPS24/RPS5/PRKCA/OAS3/RPS13/RPS27A/RPL27A/RPL36A-HNRNPH2/RPS23/NFKBIA/RPL19	36
KEGG	hsa04621	NOD-like receptor signaling pathway	30/740	184/8135	0.00112	0.07304	0.06721	TXNIP/PLCB4/IRF9/STAT2/CTSB/OAS1/CARD6/OAS2/RIPK3/TLR4/AIM2/ATG16L1/STAT1/GBP4/RELA/IL1B/RIPK2/BCL2L1/PANX1/OAS3/TRPV2/TP53BP1/HSP90AB1/MEFV/NFKBIA/NLRC4/VDAC2/FADD/CCL5/GBP1	30
KEGG	hsa04380	Osteoclast differentiation	22/740	128/8135	0.002521	0.137	0.1261	JUNB/SOCS3/IRF9/PPP3CA/STAT2/FOSL1/FOS/STAT1/MAP2K6/FOSB/RELA/IL1B/LILRB3/LILRA1/NFKBIA/TGFBR1/SIRPA/PPARG/IL1R1/AKT3/RELB/FHL2	22
KEGG	hsa04924	Renin secretion	14/740	69/8135	0.003205	0.137	0.1261	PTGER4/PLCB4/PPP3CA/CTSB/PDE3B/KCNMA1/AQP1/GUCY1A1/CACNA1D/CALM3/EDN3/PDE1A/CALM1/CLCA2	14
KEGG	hsa04371	Apelin signaling pathway	23/740	139/8135	0.003362	0.137	0.1261	GNG7/EGR1/PLCB4/PRKAA2/GNA13/CCN2/PLIN1/PDE3B/HDAC5/CALM3/RPS6/CALM1/MRAS/ADCY8/ADCY10/NOTCH3/PIK3R6/TGFBR1/SERPINE1/RYR2/CCND1/AKT3/NRF1	23
KEGG	hsa05167	Kaposi sarcoma-associated herpesvirus infection	29/740	194/8135	0.005016	0.1738	0.1599	GNG7/HLA-B/IL6ST/IRF9/PPP3CA/MYC/STAT2/HLA-A/FOS/MICB/CALM3/STAT3/VEGFA/TCF7L1/CLEC2B/STAT1/HLA-F/MAP2K6/RELA/CALM1/ICAM1/RPS27A/MICA/NFKBIA/PREX1/PIK3R6/CCND1/FADD/AKT3	29
KEGG	hsa04512	ECM-receptor interaction	16/740	88/8135	0.005331	0.1738	0.1599	SDC1/ITGA11/ITGB5/THBS4/CD44/ITGA5/THBS3/SV2A/CD47/LAMA3/LAMA4/ITGA9/THBS1/ITGA1/TNN/NPNT	16
KEGG	hsa04014	Ras signaling pathway	33/740	232/8135	0.006263	0.1856	0.1708	GNG7/ABL2/FGF10/KIT/SHC1/PLD1/FOXO4/FLT3LG/CALM3/TIAM1/VEGFA/RELA/FGF6/CALM1/RGL2/MRAS/PGF/BCL2L1/PRKCA/PLA2G2C/ZAP70/ETS1/PLAAT3/PDGFA/KSR1/NTF4/PAK1/RASA3/EXOC2/AKT3/RASAL2/PLA2G2A/RAPGEF5	33
KEGG	hsa04218	Cellular senescence	24/740	156/8135	0.007128	0.1936	0.1782	HLA-B/PPP3CA/MYC/HLA-A/PPP1CB/CHEK1/CACNA1D/CALM3/HLA-F/CCND3/MAP2K6/RELA/CALM1/MRAS/ETS1/CAPN1/TGFBR1/SERPINE1/VDAC2/CCND1/MRE11/AKT3/GADD45A/CDK2	24
KEGG	hsa05166	Human T-cell leukemia virus 1 infection	31/740	222/8135	0.01026	0.2052	0.1888	EGR1/HLA-B/PPP3CA/MYC/EGR2/HLA-A/FOSL1/FOS/CHEK1/GPS2/HLA-F/CCND3/RELA/ANAPC2/BCL2L1/ICAM1/HLA-DMB/ADCY8/ETS1/B2M/NFKBIA/HLA-DPA1/TGFBR1/VDAC2/CCND1/IL1R1/AKT3/MAP3K3/RELB/CRTC2/CDK2	31
KEGG	hsa05205	Proteoglycans in cancer	29/740	205/8135	0.01075	0.2052	0.1888	MYC/SDC1/PPP1CB/ITGB5/CD44/TLR4/FZD6/HOXD10/PLAUR/RPS6/TIAM1/STAT3/ITGA5/VEGFA/IQGAP1/MRAS/EIF4B/PRKCA/CBL/CD63/THBS1/PAK1/CCND1/ESR1/FLNB/AKT3/CAMK2D/MIR21/SMO	29
KEGG	hsa05164	Influenza A	25/740	171/8135	0.01155	0.2052	0.1888	MX1/SOCS3/IRF9/STAT2/OAS1/PML/OAS2/TLR4/STAT1/CCND3/CXCL10/RELA/IL1B/TNFSF10/ICAM1/PRKCA/HLA-DMB/OAS3/CIITA/TPSB2/NFKBIA/HLA-DPA1/FADD/CCL5/AKT3	25
KEGG	hsa04625	C-type lectin receptor signaling pathway	17/740	104/8135	0.01217	0.2052	0.1888	IRF9/PPP3CA/STAT2/EGR2/CALM3/STAT1/RELA/CALM1/IL1B/MRAS/CCL17/KSR1/NFKBIA/PAK1/PLK3/AKT3/RELB	17
KEGG	hsa04151	PI3K-Akt signaling pathway	45/740	354/8135	0.01266	0.2052	0.1888	NR4A1/GNG7/PCK1/PRKAA2/FGF10/MYC/MYB/ITGA11/KIT/PIK3AP1/ITGB5/THBS4/TLR4/FLT3LG/RPS6/ITGA5/VEGFA/THBS3/CCND3/EREG/RELA/FGF6/PKN3/PGF/EIF4B/BCL2L1/PRKCA/HSP90AB1/PDGFA/IL4R/PRLR/LAMA3/LAMA4/PIK3R6/F2R/ITGA9/THBS1/NTF4/ITGA1/CCND1/AKT3/TNN/CRTC2/CDK2/RXRA	45
KEGG	hsa05144	Malaria	10/740	50/8135	0.01316	0.2052	0.1888	ACKR1/SDC1/THBS4/TLR4/KLRC4-KLRK1/THBS3/VCAM1/IL1B/ICAM1/THBS1	10
KEGG	hsa04360	Axon guidance	26/740	182/8135	0.0135	0.2052	0.1888	UNC5C/SEMA4A/PPP3CA/PLXNA4/PLXNA2/EPHA3/SEMA3E/PLXNC1/EPHA7/EFNB1/ABLIM3/RGMA/SEMA3A/PRKCA/SEMA6B/ROBO1/MYL12B/SEMA3F/PAK1/UNC5A/ABLIM1/CAMK2D/SEMA4G/NTNG1/SMO/FES	26
KEGG	hsa04115	p53 signaling pathway	13/740	73/8135	0.01352	0.2052	0.1888	SESN3/CHEK1/CCND3/PPM1D/PMAIP1/BCL2L1/THBS1/BBC3/SERPINE1/CCND1/GADD45A/RRM2/CDK2	13
KEGG	hsa04713	Circadian entrainment	16/740	97/8135	0.01357	0.2052	0.1888	GRIA2/GNG7/PLCB4/GRIA3/RASD1/FOS/GUCY1A1/CACNA1D/CALM3/CALM1/GRIN2D/PRKCA/ADCY8/ADCY10/RYR2/CAMK2D	16
KEGG	hsa05162	Measles	21/740	139/8135	0.01385	0.2052	0.1888	MX1/IRF9/STAT2/FOS/OAS1/OAS2/TLR4/STAT3/STAT1/CCND3/RELA/IL1B/RAB9A/BCL2L1/OAS3/NFKBIA/BBC3/CCND1/FADD/AKT3/CDK2	21
KEGG	hsa05143	African trypanosomiasis	8/740	37/8135	0.01618	0.2265	0.2084	PLCB4/VCAM1/IDO1/IL1B/ICAM1/PRKCA/APOL1/LAMA4	8
KEGG	hsa03320	PPAR signaling pathway	13/740	75/8135	0.01678	0.2265	0.2084	PLTP/PCK1/FABP3/PLIN1/PLIN2/CPT1C/ACADM/SORBS1/PPARG/ME1/SLC27A5/PLIN5/RXRA	13
KEGG	hsa04659	Th17 cell differentiation	17/740	108/8135	0.01737	0.2265	0.2084	IL6ST/PPP3CA/FOS/STAT3/STAT1/RELA/IL1B/HLA-DMB/ZAP70/HSP90AB1/IL4R/NFKBIA/HLA-DPA1/TGFBR1/IL1R1/NFKBIE/RXRA	17
KEGG	hsa00410	beta-Alanine metabolism	7/740	31/8135	0.01899	0.2381	0.2191	CNDP2/ALDH6A1/ALDH3A2/AOC2/ABAT/SMOX/ALDH1B1	7
KEGG	hsa00561	Glycerolipid metabolism	11/740	61/8135	0.02027	0.2398	0.2207	AKR1B10/MBOAT1/DGKH/PLPP4/ALDH3A2/DGKI/LIPC/MBOAT2/GPAT2/ALDH1B1/DGKK	11
KEGG	hsa05031	Amphetamine addiction	12/740	69/8135	0.0206	0.2398	0.2207	GRIA2/GRIA3/PPP3CA/PPP1CB/FOS/CACNA1D/CALM3/FOSB/CALM1/GRIN2D/PRKCA/CAMK2D	12
KEGG	hsa04668	TNF signaling pathway	17/740	112/8135	0.02412	0.2712	0.2495	JUNB/SOCS3/FOS/RIPK3/CASP10/VCAM1/MAP2K6/CXCL10/RELA/IL1B/ICAM1/CEBPB/NFKBIA/IL18R1/FADD/CCL5/AKT3	17
KEGG	hsa05418	Fluid shear stress and atherosclerosis	20/740	139/8135	0.02607	0.2717	0.25	PRKAA2/SDC1/FOS/CALM3/VEGFA/VCAM1/MAP2K6/RELA/CALM1/IL1B/ICAM1/GSTO1/MGST1/GSTM3/HSP90AB1/PDGFA/GSTT1/IL1R1/AKT3/ACVR1	20
KEGG	hsa00790	Folate biosynthesis	6/740	26/8135	0.02632	0.2717	0.25	AKR1B10/GGH/PCBD1/QDPR/TPH2/SPR	6
KEGG	hsa05160	Hepatitis C	22/740	157/8135	0.02667	0.2717	0.25	CLDN25/MX1/SOCS3/IRF9/MYC/STAT2/OAS1/OAS2/STAT3/STAT1/CLDN23/CXCL10/RELA/IFIT1/OAS3/NFKBIA/CCND1/FADD/AKT3/CLDN22/CDK2/RXRA	22
KEGG	hsa04024	cAMP signaling pathway	29/740	221/8135	0.02766	0.2732	0.2514	GRIA2/PDE4B/GRIA3/RAPGEF3/PPP1CB/CFTR/FOS/ABCC4/PDE3B/PLD1/CACNA1D/CALM3/TIAM1/EDN3/RELA/CALM1/GRIN2D/PDE4A/HTR1B/ADCY8/ADCY10/NFKBIA/F2R/ATP1B3/PAK1/RYR2/PDE4C/AKT3/CAMK2D	29
KEGG	hsa00564	Glycerophospholipid metabolism	15/740	98/8135	0.03072	0.2872	0.2643	MBOAT1/DGKH/PLPP4/PLD1/LPCAT2/DGKI/PLA2G2C/PLAAT3/CEPT1/MBOAT2/PLA2G2A/LYPLA1/LPCAT4/GPAT2/DGKK	15
KEGG	hsa01524	Platinum drug resistance	12/740	73/8135	0.03084	0.2872	0.2643	MSH2/REV3L/ERCC1/PMAIP1/BCL2L1/GSTO1/MGST1/GSTM3/BBC3/GSTT1/FADD/AKT3	12
KEGG	hsa04933	AGE-RAGE signaling pathway in diabetic complications	15/740	100/8135	0.03601	0.3261	0.3001	EGR1/PLCB4/STAT3/VEGFA/STAT1/VCAM1/RELA/IL1B/ICAM1/PRKCA/TGFBR1/SERPINE1/CCND1/AKT3/NOX4	15
KEGG	hsa04720	Long-term potentiation	11/740	67/8135	0.03804	0.3352	0.3084	GRIA2/PLCB4/PPP3CA/RAPGEF3/PPP1CB/CALM3/CALM1/GRIN2D/PRKCA/ADCY8/CAMK2D	11
KEGG	hsa04910	Insulin signaling pathway	19/740	137/8135	0.04113	0.3528	0.3247	PCK1/PTPRF/SOCS3/PRKAA2/PPP1CB/SHC1/PDE3B/PRKAR1B/CALM3/RPS6/CALM1/SOCS4/HK1/PRKAR1A/PPP1R3D/CBL/PHKA1/SORBS1/AKT3	19
KEGG	hsa04610	Complement and coagulation cascades	13/740	85/8135	0.04259	0.356	0.3276	PROS1/C9/C7/CPB2/CFI/PLAUR/CD59/F2R/SERPINE1/CLU/TFPI/PROCR/SERPING1	13
KEGG	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	12/740	77/8135	0.04431	0.3597	0.331	ITGA11/ITGB5/CDH2/CACNA1D/DSG2/ITGA5/TCF7L1/ITGA9/ITGA1/RYR2/CACNG1/CTNNA2	12
KEGG	hsa05207	Chemical carcinogenesis - receptor activation	27/740	212/8135	0.04523	0.3597	0.331	AR/FGF10/MYC/PAQR8/MIRLET7A1/FOS/CACNA1D/STAT3/VEGFA/KPNA3/CCND3/RELA/FGF6/PRKCA/GSTO1/MGST1/GSTM3/ADCY8/HSP90AB1/EPHX2/KLF4/GSTT1/CCND1/ESR1/AKT3/MIR141/RXRA	27
KEGG	hsa04917	Prolactin signaling pathway	11/740	70/8135	0.05012	0.389	0.358	SOCS3/SHC1/FOS/STAT3/STAT1/RELA/SOCS4/PRLR/CCND1/ESR1/AKT3	11
KEGG	hsa03060	Protein export	5/740	23/8135	0.0521	0.3894	0.3583	HSPA5/SEC61G/SEC11C/SPCS2/IMMP1L	5
KEGG	hsa04724	Glutamatergic synapse	16/740	114/8135	0.05258	0.3894	0.3583	GRIA2/GNG7/PLCB4/GRIA3/PPP3CA/DLG4/SLC38A2/PLD1/GLUL/CACNA1D/GLS2/GRIN2D/GRIK3/PRKCA/ADCY8/SLC38A1	16
KEGG	hsa05163	Human cytomegalovirus infection	28/740	225/8135	0.05375	0.3894	0.3583	PTGER4/GNG7/PLCB4/HLA-B/PPP3CA/GNA13/MYC/HLA-A/TAP1/CALM3/STAT3/VEGFA/HLA-F/MAP2K6/RELA/CALM1/TAPBP/IL1B/TAP2/PRKCA/ADCY8/B2M/NFKBIA/CCND1/FADD/CCL5/IL1R1/AKT3	28
KEGG	hsa04145	Phagosome	20/740	152/8135	0.05857	0.4151	0.382	HLA-B/HLA-A/TAP1/ITGB5/THBS4/COLEC12/TLR4/CTSS/ITGA5/THBS3/HLA-F/TAP2/HLA-DMB/TCIRG1/THBS1/HLA-DPA1/SEC61G/ATP6V0B/TUBB8/TUBB6	20
KEGG	hsa04640	Hematopoietic cell lineage	14/740	99/8135	0.06343	0.44	0.4049	KIT/CD44/FLT3LG/ITGA5/CD24/IL11RA/IL1B/HLA-DMB/CD59/CD37/IL4R/HLA-DPA1/ITGA1/IL1R1	14
KEGG	hsa04921	Oxytocin signaling pathway	20/740	154/8135	0.06536	0.4439	0.4085	PLCB4/PPP3CA/PRKAA2/EEF2/PPP1CB/FOS/GUCY1A1/CACNA1D/CALM3/CALM1/PRKCA/ADCY8/KCNJ12/PIK3R6/RYR2/CAMK1/CCND1/CACNG1/CAMK1G/CAMK2D	20
KEGG	hsa04210	Apoptosis	18/740	136/8135	0.06697	0.4455	0.41	CTSB/FOS/PARP3/CTSS/CASP10/PARP4/RELA/PMAIP1/BCL2L1/TNFSF10/CAPN1/NFKBIA/BBC3/SPTAN1/FADD/AKT3/GADD45A/DAXX	18
KEGG	hsa00565	Ether lipid metabolism	8/740	49/8135	0.07274	0.4742	0.4364	ENPP2/PLD1/LPCAT2/PLA2G2C/PLAAT3/CEPT1/PLA2G2A/LPCAT4	8
KEGG	hsa05214	Glioma	11/740	75/8135	0.07554	0.4825	0.4441	SHC1/CALM3/CALM1/PRKCA/PDGFA/CAMK1/CCND1/AKT3/GADD45A/CAMK1G/CAMK2D	11
KEGG	hsa00480	Glutathione metabolism	9/740	58/8135	0.07697	0.4825	0.4441	LAP3/GGCT/GGT7/GSTO1/MGST1/GSTM3/PRDX6/GSTT1/RRM2	9
KEGG	hsa05212	Pancreatic cancer	11/740	76/8135	0.08145	0.4882	0.4493	BRCA2/PLD1/STAT3/VEGFA/STAT1/RELA/BCL2L1/TGFBR1/CCND1/AKT3/GADD45A	11
KEGG	hsa04514	Cell adhesion molecules	19/740	149/8135	0.08206	0.4882	0.4493	CLDN25/PTPRF/HLA-B/CADM3/SDC1/HLA-A/NLGN1/CDH2/VCAM1/HLA-F/CLDN23/ICAM1/HLA-DMB/ICAM2/ITGA9/HLA-DPA1/CNTN1/CLDN22/NTNG1	19
KEGG	hsa05332	Graft-versus-host disease	7/740	42/8135	0.08237	0.4882	0.4493	HLA-B/HLA-A/HLA-F/IL1B/KIR3DL3/HLA-DMB/HLA-DPA1	7
KEGG	hsa00330	Arginine and proline metabolism	8/740	51/8135	0.08777	0.4959	0.4563	CNDP2/CKMT1A/LAP3/ALDH3A2/P4HA3/SMOX/L3HYPDH/ALDH1B1	8
KEGG	hsa04620	Toll-like receptor signaling pathway	14/740	104/8135	0.08781	0.4959	0.4563	TLR8/FOS/TLR4/STAT1/MAP2K6/CXCL10/RELA/IL1B/NFKBIA/CXCL11/FADD/CCL5/AKT3/CXCL9	14
KEGG	hsa05210	Colorectal cancer	12/740	86/8135	0.08822	0.4959	0.4563	MYC/MSH2/FOS/TCF7L1/AXIN2/EREG/PMAIP1/TGFBR1/BBC3/CCND1/AKT3/GADD45A	12
KEGG	hsa04940	Type I diabetes mellitus	7/740	43/8135	0.09107	0.4979	0.4582	HLA-B/HLA-A/ICA1/HLA-F/IL1B/HLA-DMB/HLA-DPA1	7
KEGG	hsa04920	Adipocytokine signaling pathway	10/740	69/8135	0.09314	0.4979	0.4582	PCK1/SOCS3/PRKAA2/CPT1C/STAT3/RELA/NFKBIA/AKT3/NFKBIE/RXRA	10
KEGG	hsa05152	Tuberculosis	22/740	180/8135	0.09317	0.4979	0.4582	PPP3CA/TLR4/CALM3/CTSS/CASP10/STAT1/RELA/CALM1/IL1B/RIPK2/HLA-DMB/CIITA/CD74/TCIRG1/CEBPB/KSR1/HLA-DPA1/FADD/ATP6V0B/PLK3/AKT3/CAMK2D	22
KEGG	hsa04510	Focal adhesion	24/740	201/8135	0.1006	0.5292	0.487	ITGA11/PPP1CB/SHC1/ITGB5/THBS4/ITGA5/VEGFA/THBS3/CCND3/PGF/PRKCA/PDGFA/LAMA3/LAMA4/MYL12B/ITGA9/THBS1/PAK1/ACTN1/ITGA1/CCND1/FLNB/AKT3/TNN	24
KEGG	hsa04750	Inflammatory mediator regulation of TRP channels	13/740	98/8135	0.1063	0.5467	0.5031	PTGER4/PLCB4/PPP1CB/HTR2A/CALM3/MAP2K6/CALM1/IL1B/PRKCA/TRPV2/ADCY8/IL1R1/CAMK2D	13
KEGG	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	12/740	89/8135	0.1073	0.5467	0.5031	PPP3CA/FOS/TLR4/STAT3/STAT1/MAP2K6/RELA/ZAP70/NFKBIA/AKT3/MAP3K3/NFKBIE	12
KEGG	hsa01250	Biosynthesis of nucleotide sugars	6/740	37/8135	0.1148	0.5669	0.5217	MPI/UGP2/HK1/UAP1L1/GMDS/GNE	6
KEGG	hsa05216	Thyroid cancer	6/740	37/8135	0.1148	0.5669	0.5217	MYC/TCF7L1/CCND1/PPARG/GADD45A/RXRA	6
KEGG	hsa05224	Breast cancer	18/740	147/8135	0.1184	0.5762	0.5303	FGF10/MYC/KIT/SHC1/FOS/BRCA2/FZD6/TCF7L1/AXIN2/FGF6/HEY2/NOTCH3/NCOA3/CCND1/ESR1/AKT3/GADD45A/FRAT2	18
KEGG	hsa04072	Phospholipase D signaling pathway	18/740	148/8135	0.124	0.5947	0.5472	PLCB4/GNA13/RAPGEF3/KIT/SHC1/DGKH/PLD1/PTGFR/MRAS/DGKI/PRKCA/ADCY8/PDGFA/CYTH2/PIK3R6/F2R/AKT3/DGKK	18
KEGG	hsa00620	Pyruvate metabolism	7/740	47/8135	0.1307	0.6039	0.5557	PCK1/ALDH3A2/ME1/ACYP1/ME2/ALDH1B1/ADH7	7
KEGG	hsa01523	Antifolate resistance	5/740	30/8135	0.1316	0.6039	0.5557	GGH/FOLR1/ABCC4/RELA/IL1B	5
KEGG	hsa05321	Inflammatory bowel disease	9/740	65/8135	0.1329	0.6039	0.5557	TLR4/STAT3/STAT1/RELA/IL1B/HLA-DMB/IL4R/IL18R1/HLA-DPA1	9
KEGG	hsa05145	Toxoplasmosis	14/740	112/8135	0.1376	0.6039	0.5557	TLR4/STAT3/STAT1/MAP2K6/RELA/BCL2L1/HLA-DMB/CIITA/LAMA3/LAMA4/NFKBIA/PIK3R6/HLA-DPA1/AKT3	14
KEGG	hsa05132	Salmonella infection	28/740	249/8135	0.1396	0.6039	0.5557	MYC/FOS/RIPK3/TLR4/TCF7L1/KPNA3/MAP2K6/RELA/AHNAK2/IL1B/RIPK2/RAB9A/TNFSF10/PODXL/HSP90AB1/CYTH2/MYL12B/NFKBIA/PAK1/NLRC4/FADD/EXOC2/FLNB/SNX18/AKT3/TUBB8/PLEKHM2/TUBB6	28
KEGG	hsa00280	Valine, leucine and isoleucine degradation	7/740	48/8135	0.1418	0.6039	0.5557	ALDH6A1/ALDH3A2/BCKDHA/ACADM/ABAT/HIBADH/ALDH1B1	7
KEGG	hsa05134	Legionellosis	8/740	57/8135	0.1427	0.6039	0.5557	EEF1G/EEF1A1/TLR4/RELA/IL1B/NFKBIA/NLRC4/HSF1	8
KEGG	hsa04657	IL-17 signaling pathway	12/740	94/8135	0.1441	0.6039	0.5557	FOSL1/FOS/CXCL10/FOSB/RELA/IL1B/IL17RA/CCL17/HSP90AB1/CEBPB/NFKBIA/FADD	12
KEGG	hsa04936	Alcoholic liver disease	17/740	142/8135	0.1461	0.6039	0.5557	PRKAA2/ALDH3A2/CPT1C/TLR4/TCF7L1/MAP2K6/RELA/IL1B/IL17RA/ACADM/NFKBIA/CCND1/FADD/AKT3/ALDH1B1/ADH7/NOX4	17
KEGG	hsa05165	Human papillomavirus infection	36/740	331/8135	0.1467	0.6039	0.5557	PTGER4/MX1/HLA-B/ISG15/IRF9/STAT2/HLA-A/ITGA11/ITGB5/THBS4/FZD6/ITGA5/VEGFA/THBS3/TCF7L1/STAT1/AXIN2/HLA-F/CCND3/RELA/HEY2/NOTCH3/TCIRG1/LAMA3/LAMA4/ITGA9/THBS1/ITGA1/CCND1/FADD/ATP6V0B/AKT3/TNN/OASL/PATJ/CDK2	36
KEGG	hsa05220	Chronic myeloid leukemia	10/740	76/8135	0.1498	0.6039	0.5557	MYC/SHC1/RELA/BCL2L1/CBL/NFKBIA/TGFBR1/CCND1/AKT3/GADD45A	10
KEGG	hsa00604	Glycosphingolipid biosynthesis - ganglio series	3/740	15/8135	0.1502	0.6039	0.5557	ST3GAL5/B3GALT4/ST6GALNAC5	3
KEGG	hsa04964	Proximal tubule bicarbonate reclamation	4/740	23/8135	0.1511	0.6039	0.5557	PCK1/AQP1/GLS2/ATP1B3	4
KEGG	hsa05221	Acute myeloid leukemia	9/740	67/8135	0.1519	0.6039	0.5557	MYC/KIT/PML/STAT3/TCF7L1/RELA/PIM2/CCND1/AKT3	9
KEGG	hsa05170	Human immunodeficiency virus 1 infection	24/740	212/8135	0.1538	0.6039	0.5557	GNG7/HLA-B/PPP3CA/HLA-A/TAP1/FOS/CHEK1/WEE1/TLR4/CALM3/HLA-F/MAP2K6/RELA/CALM1/TAPBP/BCL2L1/TAP2/PRKCA/SAMHD1/B2M/NFKBIA/PAK1/FADD/AKT3	24
KEGG	hsa04010	MAPK signaling pathway	32/740	294/8135	0.1625	0.6265	0.5766	NR4A1/PPP3CA/FGF10/MYC/KIT/FOS/DUSP2/FLT3LG/CACNA1D/VEGFA/EREG/MAP2K6/RELA/FGF6/IL1B/MRAS/PGF/DUSP5/PRKCA/PDGFA/NTF4/PAK1/TGFBR1/CACNG1/IL1R1/DUSP3/FLNB/AKT3/MAP3K3/RELB/GADD45A/DAXX	32
KEGG	hsa04928	Parathyroid hormone synthesis, secretion and action	13/740	106/8135	0.1644	0.6265	0.5766	NR4A2/PDE4B/EGR1/PLCB4/GNA13/FOS/PLD1/PDE4A/PRKCA/ADCY8/PDE4C/MMP25/RXRA	13
KEGG	hsa05110	Vibrio cholerae infection	7/740	50/8135	0.1653	0.6265	0.5766	CFTR/PDIA4/TJP2/PRKCA/TCIRG1/SEC61G/ATP6V0B	7
KEGG	hsa05417	Lipid and atherosclerosis	24/740	215/8135	0.1706	0.6319	0.5815	PLCB4/PPP3CA/FOS/TLR4/CALM3/HSPA5/STAT3/VCAM1/MAP2K6/RELA/CALM1/IL1B/BCL2L1/TNFSF10/ICAM1/PRKCA/HSP90AB1/NFKBIA/ABCG1/CCL5/PPARG/AKT3/CAMK2D/RXRA	24
KEGG	hsa04922	Glucagon signaling pathway	13/740	107/8135	0.1726	0.6319	0.5815	PCK1/PLCB4/PPP3CA/PRKAA2/PDE3B/CPT1C/CALM3/CALM1/PFKP/PHKA1/AKT3/CRTC2/CAMK2D	13
KEGG	hsa05416	Viral myocarditis	8/740	60/8135	0.1754	0.6319	0.5815	ABL2/HLA-B/HLA-A/HLA-F/ICAM1/HLA-DMB/HLA-DPA1/CCND1	8
KEGG	hsa00051	Fructose and mannose metabolism	5/740	33/8135	0.1763	0.6319	0.5815	AKR1B10/MPI/PFKP/HK1/GMDS	5
KEGG	hsa04925	Aldosterone synthesis and secretion	12/740	98/8135	0.1778	0.6319	0.5815	NR4A2/NR4A1/PLCB4/CACNA1D/CALM3/CALM1/PRKCA/ADCY8/ATP1B3/CAMK1/CAMK1G/CAMK2D	12
KEGG	hsa00380	Tryptophan metabolism	6/740	42/8135	0.1783	0.6319	0.5815	CAT/ALDH3A2/IDO1/DHTKD1/TPH2/ALDH1B1	6
KEGG	hsa04727	GABAergic synapse	11/740	89/8135	0.1832	0.642	0.5908	GNG7/SLC38A2/GLUL/CACNA1D/GLS2/PRKCA/ADCY8/PLCL1/GABRE/ABAT/SLC38A1	11
KEGG	hsa00230	Purine metabolism	15/740	128/8135	0.1853	0.6427	0.5914	PDE4B/HDDC2/PDE3B/GUCY1A1/PDE1A/PDE4A/PDE5A/ADCY8/ADCY10/AMPD3/PAICS/PDE7A/PDE4C/RRM2/IMPDH1	15
KEGG	hsa04530	Tight junction	19/740	169/8135	0.1959	0.6616	0.6088	CLDN25/BVES/PRKAA2/CFTR/SYMPK/CACNA1D/AMOTL1/TIAM1/TJP2/RAP2C/CLDN23/MYL12B/ACTN1/ARHGEF18/CCND1/YBX3/PATJ/NEDD4/CLDN22	19
KEGG	hsa00120	Primary bile acid biosynthesis	3/740	17/8135	0.1968	0.6616	0.6088	CH25H/HSD17B4/SLC27A5	3
KEGG	hsa00910	Nitrogen metabolism	3/740	17/8135	0.1968	0.6616	0.6088	CA5B/GLUL/CA9	3
KEGG	hsa04662	B cell receptor signaling pathway	10/740	82/8135	0.2094	0.679	0.6248	PPP3CA/FOS/PIK3AP1/IFITM1/RELA/LILRB3/LILRA1/NFKBIA/AKT3/NFKBIE	10
KEGG	hsa04623	Cytosolic DNA-sensing pathway	8/740	63/8135	0.211	0.679	0.6248	RIPK3/POLR3B/AIM2/CXCL10/RELA/IL1B/NFKBIA/CCL5	8
KEGG	hsa04658	Th1 and Th2 cell differentiation	11/740	92/8135	0.2126	0.679	0.6248	PPP3CA/FOS/STAT1/RELA/HLA-DMB/ZAP70/NOTCH3/IL4R/NFKBIA/HLA-DPA1/NFKBIE	11
KEGG	hsa05222	Small cell lung cancer	11/740	92/8135	0.2126	0.679	0.6248	MYC/RELA/BCL2L1/LAMA3/LAMA4/NFKBIA/CCND1/AKT3/GADD45A/CDK2/RXRA	11
KEGG	hsa04972	Pancreatic secretion	12/740	102/8135	0.2149	0.679	0.6248	PLCB4/CFTR/KCNMA1/CPB2/PRKCA/PLA2G2C/ADCY8/RAB3D/ATP1B3/RYR2/CLCA2/PLA2G2A	12
KEGG	hsa04062	Chemokine signaling pathway	21/740	192/8135	0.2164	0.679	0.6248	GNG7/PLCB4/STAT2/SHC1/TIAM1/CCL27/STAT3/STAT1/CXCL10/RELA/CCL17/CXCL16/ADCY8/NFKBIA/PREX1/PIK3R6/PAK1/CXCL11/CCL5/AKT3/CXCL9	21
KEGG	hsa04630	JAK-STAT signaling pathway	18/740	162/8135	0.2182	0.679	0.6248	IL6ST/SOCS3/IRF9/IFNK/MYC/STAT2/CNTFR/STAT3/STAT1/CCND3/IL11RA/SOCS4/BCL2L1/PDGFA/IL4R/PRLR/CCND1/AKT3	18
KEGG	hsa02010	ABC transporters	6/740	45/8135	0.222	0.679	0.6248	TAP1/CFTR/ABCA8/ABCC4/TAP2/ABCG1	6
KEGG	hsa04912	GnRH signaling pathway	11/740	93/8135	0.2229	0.679	0.6248	EGR1/PLCB4/PLD1/CACNA1D/CALM3/MAP2K6/CALM1/PRKCA/ADCY8/MAP3K3/CAMK2D	11
KEGG	hsa00500	Starch and sucrose metabolism	5/740	36/8135	0.2259	0.679	0.6248	PGM2L1/GYG1/UGP2/AGL/HK1	5
KEGG	hsa00512	Mucin type O-glycan biosynthesis	5/740	36/8135	0.2259	0.679	0.6248	GALNT15/C1GALT1/GCNT1/GALNT16/GALNT10	5
KEGG	hsa01040	Biosynthesis of unsaturated fatty acids	4/740	27/8135	0.227	0.679	0.6248	HACD4/ELOVL3/HSD17B4/ELOVL4	4
KEGG	hsa05130	Pathogenic Escherichia coli infection	21/740	197/8135	0.2527	0.7387	0.6798	CLDN25/GNA13/FOS/TLR4/TMED10/CLDN23/RELA/IL1B/TNFSF10/BAIAP2L1/MYO1D/CYTH2/NFKBIA/F2R/PAK1/FADD/IL1R1/MYO5A/TUBB8/TUBB6/CLDN22	21
KEGG	hsa00514	Other types of O-glycan biosynthesis	6/740	47/8135	0.2528	0.7387	0.6798	B3GLCT/GALNT15/C1GALT1/GALNT16/ST6GAL1/GALNT10	6
KEGG	hsa04911	Insulin secretion	10/740	86/8135	0.2538	0.7387	0.6798	PCLO/PLCB4/KCNMA1/CACNA1D/PRKCA/ADCY8/ATP1B3/RYR2/RAB3A/CAMK2D	10
KEGG	hsa01212	Fatty acid metabolism	7/740	57/8135	0.2587	0.7398	0.6808	HACD4/CPT1C/ELOVL3/ACADM/HSD17B4/HSD17B8/ELOVL4	7
KEGG	hsa04390	Hippo signaling pathway	17/740	157/8135	0.2597	0.7398	0.6808	MYC/CCN2/PPP1CB/CRB1/DLG4/FZD6/TCF7L1/AXIN2/CCND3/LIMD1/TGFBR1/BBC3/SERPINE1/CCND1/CTNNA2/GLI2/PATJ	17
KEGG	hsa05330	Allograft rejection	5/740	38/8135	0.261	0.7398	0.6808	HLA-B/HLA-A/HLA-F/HLA-DMB/HLA-DPA1	5
KEGG	hsa05140	Leishmaniasis	9/740	77/8135	0.2643	0.7398	0.6808	EEF1A1/FOS/TLR4/STAT1/RELA/IL1B/HLA-DMB/NFKBIA/HLA-DPA1	9
KEGG	hsa04020	Calcium signaling pathway	25/740	240/8135	0.2655	0.7398	0.6808	PLCB4/PPP3CA/FGF10/HTR2A/ASPH/TRDN/CACNA1D/CALM3/VEGFA/PDE1A/FGF6/CALM1/GRIN2D/PTGFR/PRKCA/ADCY8/PHKA1/PDGFA/F2R/TACR3/VDAC2/RYR2/CAMK1/CAMK1G/CAMK2D	25
KEGG	hsa03010	Ribosome	17/740	158/8135	0.2683	0.7412	0.6821	RPS3A/RPL10A/RPLP0/RPS18/RPL24/RPS6/RPL11/RPL36AL/RPS24/RPS5/RPS13/RPS27A/RPL27A/RPL36A-HNRNPH2/RPS23/MRPL10/RPL19	17
KEGG	hsa05213	Endometrial cancer	7/740	58/8135	0.2732	0.743	0.6838	MYC/TCF7L1/AXIN2/CCND1/AKT3/CTNNA2/GADD45A	7
KEGG	hsa04931	Insulin resistance	12/740	108/8135	0.2759	0.743	0.6838	PCK1/PTPRF/SOCS3/PRKAA2/PPP1CB/STAT3/RELA/PPP1R3D/NFKBIA/AKT3/CRTC2/SLC27A5	12
KEGG	hsa00520	Amino sugar and nucleotide sugar metabolism	6/740	49/8135	0.2848	0.743	0.6838	MPI/UGP2/HK1/UAP1L1/GMDS/GNE	6
KEGG	hsa04722	Neurotrophin signaling pathway	13/740	119/8135	0.285	0.743	0.6838	BEX3/SHC1/CALM3/RELA/CALM1/RIPK2/NFKBIA/NTF4/AKT3/MAP3K3/NFKBIE/CAMK2D/MAGED1	13
KEGG	hsa04935	Growth hormone synthesis, secretion and action	13/740	119/8135	0.285	0.743	0.6838	PLCB4/JUNB/SOCS3/SHC1/FOS/CACNA1D/STAT3/STAT1/MAP2K6/PRKCA/ADCY8/ADCY10/AKT3	13
KEGG	hsa04066	HIF-1 signaling pathway	12/740	109/8135	0.2866	0.743	0.6838	TLR4/RPS6/STAT3/VEGFA/RELA/PFKP/PRKCA/HK1/ENO2/SERPINE1/AKT3/CAMK2D	12
KEGG	hsa04261	Adrenergic signaling in cardiomyocytes	16/740	150/8135	0.2882	0.743	0.6838	PLCB4/RAPGEF3/PPP1CB/CACNA1D/CALM3/CALM1/PRKCA/ADCY8/PIK3R6/ATP1B3/RYR2/SCN1B/CACNG1/AKT3/TPM1/CAMK2D	16
KEGG	hsa01521	EGFR tyrosine kinase inhibitor resistance	9/740	79/8135	0.2895	0.743	0.6838	SHC1/RPS6/STAT3/VEGFA/BCL2L1/PRKCA/PDGFA/AXL/AKT3	9
KEGG	hsa03018	RNA degradation	9/740	79/8135	0.2895	0.743	0.6838	BTG2/EXOSC6/PATL1/TOB1/PFKP/ENO2/BTG4/BTG1/PABPC1L	9
KEGG	hsa05033	Nicotine addiction	5/740	40/8135	0.2972	0.7478	0.6882	GRIA2/GRIA3/CHRNA6/GRIN2D/GABRE	5
KEGG	hsa05410	Hypertrophic cardiomyopathy	10/740	90/8135	0.301	0.7478	0.6882	PRKAA2/ITGA11/ITGB5/CACNA1D/ITGA5/ITGA9/ITGA1/RYR2/CACNG1/TPM1	10
KEGG	hsa04979	Cholesterol metabolism	6/740	50/8135	0.3011	0.7478	0.6882	PLTP/APOC1/APOE/LIPC/VDAC2/OSBPL5	6
KEGG	hsa04730	Long-term depression	7/740	60/8135	0.3027	0.7478	0.6882	GRIA2/PLCB4/GRIA3/GNA13/GUCY1A1/PRKCA/PPP1R17	7
KEGG	hsa04650	Natural killer cell mediated cytotoxicity	14/740	131/8135	0.303	0.7478	0.6882	HLA-B/PPP3CA/HLA-A/SHC1/MICB/KLRC4-KLRK1/KIR3DL3/TNFSF10/ICAM1/PRKCA/ZAP70/ICAM2/MICA/PAK1	14
KEGG	hsa00052	Galactose metabolism	4/740	31/8135	0.3102	0.7478	0.6882	AKR1B10/UGP2/PFKP/HK1	4
KEGG	hsa05032	Morphine addiction	10/740	91/8135	0.3132	0.7478	0.6882	PDE4B/GNG7/PDE3B/PDE1A/PDE4A/PRKCA/ADCY8/GABRE/PDE7A/PDE4C	10
KEGG	hsa03440	Homologous recombination	5/740	41/8135	0.3156	0.7478	0.6882	BRCA2/RAD52/RAD54L/MRE11/TOPBP1	5
KEGG	hsa05219	Bladder cancer	5/740	41/8135	0.3156	0.7478	0.6882	MYC/TYMP/VEGFA/THBS1/CCND1	5
KEGG	hsa05131	Shigellosis	25/740	247/8135	0.3159	0.7478	0.6882	PLCB4/CD44/TLR4/FOXO4/ATG16L1/ITGA5/RELA/IL1B/RIPK2/BCL2L1/TIFA/HK1/RPS27A/CYTH2/UBE2D4/CAPN1/MYL12B/NFKBIA/ACTN1/NLRC4/CCL5/IL1R1/AKT3/WIPI2/RRAGC	25
KEGG	hsa00590	Arachidonic acid metabolism	7/740	61/8135	0.3177	0.7478	0.6882	PTGDS/PTGS1/PRXL2B/PLA2G2C/PLAAT3/EPHX2/PLA2G2A	7
KEGG	hsa04550	Signaling pathways regulating pluripotency of stem cells	15/740	143/8135	0.3196	0.7478	0.6882	MEIS1/IL6ST/MYC/JARID2/LHX5/FZD6/STAT3/AXIN2/PCGF5/POU5F1/KLF4/PCGF1/AKT3/DLX5/ACVR1	15
KEGG	hsa05142	Chagas disease	11/740	102/8135	0.3225	0.7478	0.6882	PLCB4/FOS/TLR4/RELA/IL1B/NFKBIA/TGFBR1/SERPINE1/FADD/CCL5/AKT3	11
KEGG	hsa00340	Histidine metabolism	3/740	22/8135	0.3234	0.7478	0.6882	CNDP2/ALDH3A2/ALDH1B1	3
KEGG	hsa00640	Propanoate metabolism	4/740	32/8135	0.3316	0.7559	0.6956	ALDH6A1/BCKDHA/ABAT/ECHDC1	4
KEGG	hsa04215	Apoptosis - multiple species	4/740	32/8135	0.3316	0.7559	0.6956	PMAIP1/BCL2L1/BBC3/FADD	4
KEGG	hsa03450	Non-homologous end-joining	2/740	13/8135	0.3341	0.7563	0.696	MRE11/FEN1	2
KEGG	hsa05323	Rheumatoid arthritis	10/740	93/8135	0.3378	0.7594	0.6989	FOS/TLR4/VEGFA/IL1B/ICAM1/HLA-DMB/TCIRG1/HLA-DPA1/CCL5/ATP6V0B	10
KEGG	hsa04064	NF-kappa B signaling pathway	11/740	104/8135	0.3459	0.7724	0.7108	TLR4/VCAM1/RELA/IL1B/BCL2L1/ICAM1/ZAP70/NFKBIA/IL1R1/RELB/GADD45A	11
KEGG	hsa03430	Mismatch repair	3/740	23/8135	0.3493	0.7746	0.7128	MSH2/EXO1/MLH3	3
KEGG	hsa00071	Fatty acid degradation	5/740	43/8135	0.3528	0.7771	0.7151	ALDH3A2/CPT1C/ACADM/ALDH1B1/ADH7	5
KEGG	hsa04015	Rap1 signaling pathway	21/740	210/8135	0.3567	0.7804	0.7181	PLCB4/FGF10/RAPGEF3/KIT/DOCK4/CALM3/TIAM1/SIPA1L2/VEGFA/MAP2K6/FGF6/CALM1/MRAS/PGF/PRKCA/ADCY8/PDGFA/F2R/THBS1/AKT3/RAPGEF5	21
KEGG	hsa04012	ErbB signaling pathway	9/740	85/8135	0.3679	0.7953	0.7319	ABL2/MYC/SHC1/EREG/PRKCA/CBL/PAK1/AKT3/CAMK2D	9
KEGG	hsa04217	Necroptosis	16/740	159/8135	0.3737	0.7953	0.7319	SMPD1/IRF9/STAT2/RIPK3/TLR4/GLUL/STAT3/STAT1/IL1B/TNFSF10/HSP90AB1/CAPN1/VDAC2/CHMP1B/FADD/CAMK2D	16
KEGG	hsa00040	Pentose and glucuronate interconversions	4/740	34/8135	0.3744	0.7953	0.7319	AKR1B10/XYLB/UGP2/RPE	4
KEGG	hsa05414	Dilated cardiomyopathy	10/740	96/8135	0.3753	0.7953	0.7319	ITGA11/ITGB5/CACNA1D/ITGA5/ADCY8/ITGA9/ITGA1/RYR2/CACNG1/TPM1	10
KEGG	hsa05226	Gastric cancer	15/740	149/8135	0.3795	0.7953	0.7319	FGF10/MYC/SHC1/FZD6/TCF7L1/AXIN2/FGF6/TGFBR1/CCND1/AKT3/CTNNA2/GADD45A/CDK2/RXRA/FRAT2	15
KEGG	hsa04742	Taste transduction	9/740	86/8135	0.3812	0.7953	0.7319	TAS2R14/TAS2R19/PLCB4/TAS2R40/PDE1A/HTR1B/TAS2R20/ADCY8/TAS2R43	9
KEGG	hsa04971	Gastric acid secretion	8/740	76/8135	0.3875	0.7953	0.7319	PLCB4/CFTR/CALM3/CALM1/PRKCA/ADCY8/ATP1B3/CAMK2D	8
KEGG	hsa05133	Pertussis	8/740	76/8135	0.3875	0.7953	0.7319	FOS/TLR4/CALM3/ITGA5/RELA/CALM1/IL1B/SERPING1	8
KEGG	hsa05206	MicroRNAs in cancer	30/740	310/8135	0.3876	0.7953	0.7319	MIRLET7C/MYC/MIR125B2/ZFPM2/MIR99A/MIRLET7A1/SHC1/CD44/HOXD10/HDAC5/GLS2/STAT3/ITGA5/VEGFA/MIR16-1/KIF23/PRKCA/NOTCH3/PDGFA/MIR199B/THBS1/ST14/CCND1/MIR141/TNN/MIR152/TPM1/SOX4/MIR21/MIR210	30
KEGG	hsa05215	Prostate cancer	10/740	97/8135	0.3879	0.7953	0.7319	AR/TCF7L1/RELA/SPINT1/HSP90AB1/PDGFA/NFKBIA/CCND1/AKT3/CDK2	10
KEGG	hsa05231	Choline metabolism in cancer	10/740	98/8135	0.4005	0.8063	0.742	DGKH/FOS/PLD1/DGKI/PRKCA/PDGFA/SLC44A2/AKT3/LYPLA1/DGKK	10
KEGG	hsa00592	alpha-Linolenic acid metabolism	3/740	25/8135	0.4005	0.8063	0.742	PLA2G2C/PLAAT3/PLA2G2A	3
KEGG	hsa04923	Regulation of lipolysis in adipocytes	6/740	56/8135	0.4012	0.8063	0.742	PTGS1/PLIN1/PDE3B/ADCY8/PLAAT3/AKT3	6
KEGG	hsa05161	Hepatitis B	16/740	162/8135	0.4031	0.8063	0.742	MYC/STAT2/EGR2/FOS/TLR4/STAT3/CASP10/STAT1/MAP2K6/RELA/PRKCA/NFKBIA/TGFBR1/FADD/AKT3/CDK2	16
KEGG	hsa04930	Type II diabetes mellitus	5/740	46/8135	0.4088	0.8091	0.7446	SOCS3/CACNA1D/MAFA/SOCS4/HK1	5
KEGG	hsa00010	Glycolysis / Gluconeogenesis	7/740	67/8135	0.4095	0.8091	0.7446	PCK1/ALDH3A2/PFKP/HK1/ENO2/ALDH1B1/ADH7	7
KEGG	hsa04068	FoxO signaling pathway	13/740	131/8135	0.4137	0.8125	0.7477	PCK1/CAT/PRKAA2/FOXO4/STAT3/TNFSF10/FBXO32/TGFBR1/CCND1/PLK3/AKT3/GADD45A/CDK2	13
KEGG	hsa03030	DNA replication	4/740	36/8135	0.417	0.814	0.7491	PRIM2/MCM4/POLA2/FEN1	4
KEGG	hsa04919	Thyroid hormone signaling pathway	12/740	121/8135	0.4214	0.8147	0.7498	PLCB4/MYC/STAT1/PFKP/PRKCA/NOTCH3/NCOA3/ATP1B3/CCND1/ESR1/AKT3/RXRA	12
KEGG	hsa04728	Dopaminergic synapse	13/740	132/8135	0.4247	0.8147	0.7498	GRIA2/GNG7/PLCB4/GRIA3/PPP3CA/PPP1CB/FOS/CACNA1D/CALM3/CALM1/PRKCA/AKT3/CAMK2D	13
KEGG	hsa04061	Viral protein interaction with cytokine and cytokine receptor	10/740	100/8135	0.4258	0.8147	0.7498	IL6ST/IL34/CCL27/CXCL10/CCL17/TNFSF10/IL18R1/CXCL11/CCL5/CXCL9	10
KEGG	hsa04973	Carbohydrate digestion and absorption	5/740	47/8135	0.4274	0.8147	0.7498	PLCB4/CACNA1D/HK1/ATP1B3/AKT3	5
KEGG	hsa00250	Alanine, aspartate and glutamate metabolism	4/740	37/8135	0.438	0.8178	0.7526	GLUL/GLS2/ASNS/ABAT	4
KEGG	hsa00983	Drug metabolism - other enzymes	8/740	80/8135	0.4446	0.8178	0.7526	TYMP/CES1/GSTO1/MGST1/GSTM3/GSTT1/RRM2/IMPDH1	8
KEGG	hsa04270	Vascular smooth muscle contraction	13/740	134/8135	0.4467	0.8178	0.7526	PLCB4/GNA13/PPP1CB/KCNMA1/GUCY1A1/CACNA1D/CALM3/EDN3/CALM1/PRKCA/PLA2G2C/ADCY8/PLA2G2A	13
KEGG	hsa00062	Fatty acid elongation	3/740	27/8135	0.4506	0.8178	0.7526	HACD4/ELOVL3/ELOVL4	3
KEGG	hsa05146	Amoebiasis	10/740	102/8135	0.4511	0.8178	0.7526	PLCB4/C9/TLR4/RELA/IL1B/PRKCA/LAMA3/LAMA4/ACTN1/IL1R1	10
KEGG	hsa04022	cGMP-PKG signaling pathway	16/740	167/8135	0.4525	0.8178	0.7526	PLCB4/PPP3CA/GNA13/PPP1CB/PDE3B/KCNMA1/GUCY1A1/CACNA1D/CALM3/CALM1/PDE5A/ADCY8/PIK3R6/ATP1B3/VDAC2/AKT3	16
KEGG	hsa04725	Cholinergic synapse	11/740	113/8135	0.4536	0.8178	0.7526	GNG7/PLCB4/FOS/CACNA1D/CHRNA6/PRKCA/ADCY8/KCNJ12/PIK3R6/AKT3/CAMK2D	11
KEGG	hsa04622	RIG-I-like receptor signaling pathway	7/740	70/8135	0.4555	0.8178	0.7526	ISG15/IFNK/CASP10/CXCL10/RELA/NFKBIA/FADD	7
KEGG	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	7/740	70/8135	0.4555	0.8178	0.7526	RELA/TCIRG1/ADAM10/NFKBIA/PAK1/CCL5/ATP6V0B	7
KEGG	hsa05230	Central carbon metabolism in cancer	7/740	70/8135	0.4555	0.8178	0.7526	MYC/KIT/GLS2/SLC7A5/PFKP/HK1/AKT3	7
KEGG	hsa05340	Primary immunodeficiency	4/740	38/8135	0.4589	0.8178	0.7526	TAP1/TAP2/ZAP70/CIITA	4
KEGG	hsa05225	Hepatocellular carcinoma	16/740	168/8135	0.4623	0.8178	0.7526	MYC/SHC1/FZD6/TCF7L1/AXIN2/BCL2L1/PRKCA/GSTO1/MGST1/GSTM3/TGFBR1/GSTT1/CCND1/AKT3/GADD45A/FRAT2	16
KEGG	hsa04974	Protein digestion and absorption	10/740	103/8135	0.4636	0.8178	0.7526	SLC38A2/CPB2/COL8A2/DPP4/SLC36A1/COL28A1/PGA4/ATP1B3/COL8A1/COL10A1	10
KEGG	hsa05030	Cocaine addiction	5/740	49/8135	0.4641	0.8178	0.7526	GRIA2/DLG4/FOSB/RELA/GRIN2D	5
KEGG	hsa04520	Adherens junction	7/740	71/8135	0.4706	0.8212	0.7557	PTPRF/TCF7L1/IQGAP1/SORBS1/TGFBR1/ACTN1/CTNNA2	7
KEGG	hsa04970	Salivary secretion	9/740	93/8135	0.4747	0.8212	0.7557	PLCB4/CST3/KCNMA1/GUCY1A1/CALM3/CALM1/PRKCA/ADCY8/ATP1B3	9
KEGG	hsa00650	Butanoate metabolism	3/740	28/8135	0.475	0.8212	0.7557	ABAT/ACSM2A/ACSM2B	3
KEGG	hsa01200	Carbon metabolism	11/740	115/8135	0.4775	0.8212	0.7557	ALDH6A1/CAT/PSPH/IDNK/PFKP/SDHA/HK1/ENO2/ME1/RPE/ME2	11
KEGG	hsa04110	Cell cycle	12/740	126/8135	0.4786	0.8212	0.7557	CDC7/MYC/CHEK1/WEE1/CCND3/ANAPC2/MCM4/ORC6/ORC4/CCND1/GADD45A/CDK2	12
KEGG	hsa04137	Mitophagy - animal	7/740	72/8135	0.4857	0.829	0.7629	TOMM7/OPTN/RELA/MRAS/BCL2L1/RPS27A/RHOT1	7
KEGG	hsa04141	Protein processing in endoplasmic reticulum	16/740	171/8135	0.4918	0.835	0.7684	UBQLN3/PDIA4/HSPA5/NPLOC4/LMAN2/MAN1C1/HSP90AB1/PDIA6/UBE2D4/CAPN1/SEC61G/UBQLN1/SSR2/MAN1A1/UBXN8/DDOST	16
KEGG	hsa00591	Linoleic acid metabolism	3/740	29/8135	0.4989	0.8383	0.7715	PLA2G2C/PLAAT3/PLA2G2A	3
KEGG	hsa04744	Phototransduction	3/740	29/8135	0.4989	0.8383	0.7715	SLC24A1/CALM3/CALM1	3
KEGG	hsa00310	Lysine degradation	6/740	63/8135	0.5164	0.8568	0.7885	PRDM6/ALDH3A2/DHTKD1/SUV39H2/PRDM2/ALDH1B1	6
KEGG	hsa05217	Basal cell carcinoma	6/740	63/8135	0.5164	0.8568	0.7885	FZD6/TCF7L1/AXIN2/GADD45A/GLI2/SMO	6
KEGG	hsa00600	Sphingolipid metabolism	5/740	52/8135	0.5178	0.8568	0.7885	SMPD1/PSAP/SPTLC1/CERS5/DEGS1	5
KEGG	hsa00030	Pentose phosphate pathway	3/740	30/8135	0.5222	0.8587	0.7902	IDNK/PFKP/RPE	3
KEGG	hsa04071	Sphingolipid signaling pathway	11/740	119/8135	0.5245	0.8587	0.7902	PLCB4/SMPD1/GNA13/PLD1/RELA/SPTLC1/PRKCA/CERS5/S1PR3/DEGS1/AKT3	11
KEGG	hsa04070	Phosphatidylinositol signaling system	9/740	97/8135	0.5268	0.8587	0.7902	PLCB4/DGKH/CALM3/CALM1/DGKI/PRKCA/PIP4K2A/MTMR14/DGKK	9
KEGG	hsa04961	Endocrine and other factor-regulated calcium reabsorption	5/740	53/8135	0.5352	0.8637	0.7948	PLCB4/PRKCA/ATP1B3/ESR1/AP2B1	5
KEGG	hsa05320	Autoimmune thyroid disease	5/740	53/8135	0.5352	0.8637	0.7948	HLA-B/HLA-A/HLA-F/HLA-DMB/HLA-DPA1	5
KEGG	hsa04260	Cardiac muscle contraction	8/740	87/8135	0.5418	0.8701	0.8007	ASPH/TRDN/CACNA1D/COX6A1/ATP1B3/RYR2/CACNG1/TPM1	8
KEGG	hsa03460	Fanconi anemia pathway	5/740	54/8135	0.5523	0.8786	0.8085	BRCA2/REV3L/ERCC1/UBE2T/FANCI	5
KEGG	hsa00100	Steroid biosynthesis	2/740	20/8135	0.5547	0.8786	0.8085	NSDHL/CYP51A1	2
KEGG	hsa04540	Gap junction	8/740	88/8135	0.5552	0.8786	0.8085	PLCB4/HTR2A/GUCY1A1/PRKCA/ADCY8/PDGFA/TUBB8/TUBB6	8
KEGG	hsa04310	Wnt signaling pathway	15/740	167/8135	0.5608	0.8832	0.8127	PLCB4/PPP3CA/MYC/FOSL1/WIF1/VANGL1/FZD6/TCF7L1/AXIN2/CCND3/PRKCA/DAAM2/CCND1/CAMK2D/FRAT2	15
KEGG	hsa04136	Autophagy - other	3/740	32/8135	0.567	0.8866	0.8159	ATG16L1/WIPI2/ATG10	3
KEGG	hsa04976	Bile secretion	8/740	89/8135	0.5684	0.8866	0.8159	CFTR/ABCC4/AQP1/ADCY8/ATP1B3/SLC10A2/SLC27A5/RXRA	8
KEGG	hsa04916	Melanogenesis	9/740	101/8135	0.5771	0.8922	0.821	PLCB4/KIT/FZD6/CALM3/TCF7L1/CALM1/PRKCA/ADCY8/CAMK2D	9
KEGG	hsa04611	Platelet activation	11/740	124/8135	0.5813	0.8922	0.821	PTGS1/PLCB4/GNA13/PPP1CB/GUCY1A1/ADCY8/MYL12B/PIK3R6/F2R/SNAP23/AKT3	11
KEGG	hsa00770	Pantothenate and CoA biosynthesis	2/740	21/8135	0.5818	0.8922	0.821	ALDH3A2/ALDH1B1	2
KEGG	hsa04340	Hedgehog signaling pathway	5/740	56/8135	0.5855	0.8922	0.821	EVC2/HHAT/CCND1/GLI2/SMO	5
KEGG	hsa03410	Base excision repair	3/740	33/8135	0.5884	0.8922	0.821	PARP3/PARP4/FEN1	3
KEGG	hsa04130	SNARE interactions in vesicular transport	3/740	33/8135	0.5884	0.8922	0.821	BET1/STX11/SNAP23	3
KEGG	hsa05202	Transcriptional misregulation in cancer	17/740	193/8135	0.5934	0.8957	0.8242	MEIS1/GRIA3/MYC/PML/ETV7/RELA/ETV6/SPINT1/BCL2L1/TSPAN7/PDGFA/CEBPB/EYA1/NR4A3/PPARG/GADD45A/RXRA	17
KEGG	hsa04670	Leukocyte transendothelial migration	10/740	114/8135	0.5965	0.896	0.8245	CLDN25/RAPGEF3/VCAM1/CLDN23/ICAM1/PRKCA/MYL12B/ACTN1/CTNNA2/CLDN22	10
KEGG	hsa05135	Yersinia infection	12/740	137/8135	0.5991	0.896	0.8245	SKAP2/FOS/TLR4/ITGA5/MAP2K6/RELA/IL1B/ZAP70/MEFV/NFKBIA/NLRC4/AKT3	12
KEGG	hsa00220	Arginine biosynthesis	2/740	22/8135	0.6076	0.9006	0.8288	GLUL/GLS2	2
KEGG	hsa04726	Serotonergic synapse	10/740	115/8135	0.6078	0.9006	0.8288	GNG7/PTGS1/PLCB4/RAPGEF3/HTR2A/CACNA1D/APP/HTR1B/PRKCA/TPH2	10
KEGG	hsa04810	Regulation of actin cytoskeleton	19/740	218/8135	0.6138	0.903	0.831	GNA13/FGF10/ITGA11/PPP1CB/ITGB5/TMSB4X/TIAM1/ITGA5/FGF6/IQGAP1/MRAS/PDGFA/PIP4K2A/MYL12B/F2R/ITGA9/PAK1/ACTN1/ITGA1	19
KEGG	hsa00920	Sulfur metabolism	1/740	10/8135	0.6149	0.903	0.831	SUOX	1
KEGG	hsa04926	Relaxin signaling pathway	11/740	129/8135	0.635	0.9282	0.8542	GNG7/PLCB4/SHC1/FOS/VEGFA/RELA/PRKCA/ADCY8/NFKBIA/TGFBR1/AKT3	11
KEGG	hsa01240	Biosynthesis of cofactors	13/740	153/8135	0.6444	0.9373	0.8625	GGH/MPI/CMPK2/ALDH3A2/RFK/NMNAT1/IDO1/UGP2/MTHFD2L/FLAD1/SPR/FECH/ALDH1B1	13
KEGG	hsa05218	Melanoma	6/740	72/8135	0.6498	0.9373	0.8625	FGF10/FGF6/PDGFA/CCND1/AKT3/GADD45A	6
KEGG	hsa05223	Non-small cell lung cancer	6/740	72/8135	0.6498	0.9373	0.8625	STAT3/PRKCA/CCND1/AKT3/GADD45A/RXRA	6
KEGG	hsa05017	Spinocerebellar ataxia	12/740	143/8135	0.6592	0.9465	0.871	GRIA2/PLCB4/GRIA3/FGF14/GRIN2D/PRKCA/PSMA4/VDAC2/PSMA6/AKT3/WIPI2/KCND3	12
KEGG	hsa04152	AMPK signaling pathway	10/740	120/8135	0.662	0.9465	0.871	PCK1/PRKAA2/EEF2/CFTR/CPT1C/PFKP/CCND1/PPARG/AKT3/CRTC2	10
KEGG	hsa04142	Lysosome	11/740	132/8135	0.6654	0.9472	0.8716	CTNS/SMPD1/CTSB/PSAP/CTSS/MAN2B1/SLC17A5/TCIRG1/CD63/ATP6V0B/SUMF1	11
KEGG	hsa01522	Endocrine resistance	8/740	98/8135	0.6783	0.958	0.8816	SHC1/FOS/ADCY8/NOTCH3/NCOA3/CCND1/ESR1/AKT3	8
KEGG	hsa00510	N-Glycan biosynthesis	4/740	50/8135	0.6788	0.958	0.8816	MAN1C1/ST6GAL1/MAN1A1/DDOST	4
KEGG	hsa05203	Viral carcinogenesis	17/740	204/8135	0.6854	0.9597	0.8831	HLA-B/IL6ST/IRF9/EGR2/HLA-A/CHEK1/GTF2A1L/HDAC5/STAT3/HLA-F/CCND3/RELA/PMAIP1/NFKBIA/ACTN1/CCND1/CDK2	17
KEGG	hsa01230	Biosynthesis of amino acids	6/740	75/8135	0.6888	0.9597	0.8831	GLUL/PSPH/PFKP/ENO2/ASNS/RPE	6
KEGG	hsa04918	Thyroid hormone synthesis	6/740	75/8135	0.6888	0.9597	0.8831	PLCB4/PDIA4/HSPA5/PRKCA/ADCY8/ATP1B3	6
KEGG	hsa00563	Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	2/740	26/8135	0.6987	0.968	0.8908	GPLD1/PIGV	2
KEGG	hsa00513	Various types of N-glycan biosynthesis	3/740	39/8135	0.7019	0.968	0.8908	MAN1C1/MAN1A1/DDOST	3
KEGG	hsa04929	GnRH secretion	5/740	64/8135	0.7037	0.968	0.8908	PLCB4/CACNA1D/HCN1/PRKCA/AKT3	5
KEGG	hsa04211	Longevity regulating pathway	7/740	89/8135	0.7115	0.9746	0.8969	CAT/PRKAA2/SESN3/RELA/ADCY8/PPARG/AKT3	7
KEGG	hsa04915	Estrogen signaling pathway	11/740	138/8135	0.7216	0.9843	0.9058	PLCB4/SHC1/FOS/CALM3/CALM1/KRT38/ADCY8/HSP90AB1/NCOA3/ESR1/AKT3	11
KEGG	hsa05022	Pathways of neurodegeneration - multiple diseases	40/740	476/8135	0.7297	0.9885	0.9097	GRIA2/PLCB4/CAT/GRIA3/PPP3CA/DLG4/DNAH6/FZD6/CACNA1D/CALM3/APP/HSPA5/OPTN/AXIN2/MAP2K6/RELA/DNAH3/CALM1/GRIN2D/IL1B/BCL2L1/SDHA/PRKCA/COX6A1/RPS27A/CAPN1/PSMA4/VDAC2/RYR2/PSMA6/FADD/WIPI2/TUBB8/TUBB6/DNALI1/DAXX/MAP3K10/CAMK2D/NOX4/FRAT2	40
KEGG	hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	1/740	14/8135	0.7372	0.9885	0.9097	CHST1	1
KEGG	hsa04660	T cell receptor signaling pathway	8/740	104/8135	0.7412	0.9885	0.9097	PPP3CA/FOS/RELA/ZAP70/NFKBIA/PAK1/AKT3/NFKBIE	8
KEGG	hsa04140	Autophagy - animal	11/740	141/8135	0.7473	0.9885	0.9097	PRKAA2/CTSB/ATG16L1/MRAS/BCL2L1/DEPTOR/AKT3/WIPI2/ATG10/RRAGC/MTMR14	11
KEGG	hsa04060	Cytokine-cytokine receptor interaction	24/740	295/8135	0.7498	0.9885	0.9097	IL16/IL6ST/IFNK/CNTFR/IL34/CCL27/CXCL10/IL11RA/IL1B/IL17RA/CCL17/TNFSF10/CXCL16/IL32/IL4R/PRLR/IL18R1/TGFBR1/CXCL11/CD70/CCL5/IL1R1/CXCL9/ACVR1	24
KEGG	hsa04392	Hippo signaling pathway - multiple species	2/740	29/8135	0.755	0.9885	0.9097	LIMD1/PAK1	2
KEGG	hsa04120	Ubiquitin mediated proteolysis	11/740	142/8135	0.7556	0.9885	0.9097	SOCS3/PML/ANAPC2/RPS27A/CBL/HERC3/UBE2D4/UBE2E1/NEDD4/UBE2A/FBXO4	11
KEGG	hsa00603	Glycosphingolipid biosynthesis - globo and isoglobo series	1/740	15/8135	0.7611	0.9885	0.9097	A4GALT	1
KEGG	hsa00730	Thiamine metabolism	1/740	15/8135	0.7611	0.9885	0.9097	THTPA	1
KEGG	hsa04934	Cushing syndrome	12/740	155/8135	0.7629	0.9885	0.9097	NR4A1/PLCB4/RASD1/FZD6/CACNA1D/TCF7L1/AXIN2/ADCY8/CCND1/WDR5B/CAMK2D/CDK2	12
KEGG	hsa04350	TGF-beta signaling pathway	7/740	94/8135	0.7635	0.9885	0.9097	MYC/RGMA/THBS1/TGFBR1/FMOD/GREM2/ACVR1	7
KEGG	hsa04150	mTOR signaling pathway	12/740	156/8135	0.7705	0.9885	0.9097	PRKAA2/GRB10/FZD6/RPS6/SLC7A5/EIF4B/PRR5L/PRKCA/MAPKAP1/DEPTOR/AKT3/RRAGC	12
KEGG	hsa00020	Citrate cycle (TCA cycle)	2/740	30/8135	0.7716	0.9885	0.9097	PCK1/SDHA	2
KEGG	hsa00053	Ascorbate and aldarate metabolism	2/740	30/8135	0.7716	0.9885	0.9097	ALDH3A2/ALDH1B1	2
KEGG	hsa00630	Glyoxylate and dicarboxylate metabolism	2/740	30/8135	0.7716	0.9885	0.9097	CAT/GLUL	2
KEGG	hsa00360	Phenylalanine metabolism	1/740	16/8135	0.7829	0.9885	0.9097	AOC2	1
KEGG	hsa00430	Taurine and hypotaurine metabolism	1/740	16/8135	0.7829	0.9885	0.9097	GGT7	1
KEGG	hsa00240	Pyrimidine metabolism	4/740	58/8135	0.7861	0.9885	0.9097	HDDC2/CMPK2/TYMP/RRM2	4
KEGG	hsa04710	Circadian rhythm	2/740	31/8135	0.7873	0.9885	0.9097	PRKAA2/CRY1	2
KEGG	hsa05310	Asthma	2/740	31/8135	0.7873	0.9885	0.9097	HLA-DMB/HLA-DPA1	2
KEGG	hsa00982	Drug metabolism - cytochrome P450	5/740	72/8135	0.7963	0.9885	0.9097	GSTO1/MGST1/GSTM3/GSTT1/ADH7	5
KEGG	hsa04330	Notch signaling pathway	4/740	59/8135	0.7972	0.9885	0.9097	DTX3L/APH1A/HEY2/NOTCH3	4
KEGG	hsa04370	VEGF signaling pathway	4/740	59/8135	0.7972	0.9885	0.9097	PPP3CA/VEGFA/PRKCA/AKT3	4
KEGG	hsa01232	Nucleotide metabolism	6/740	85/8135	0.7975	0.9885	0.9097	HDDC2/CMPK2/TYMP/AMPD3/RRM2/IMPDH1	6
KEGG	hsa00450	Selenocompound metabolism	1/740	17/8135	0.8027	0.9901	0.9112	SEPHS1	1
KEGG	hsa00562	Inositol phosphate metabolism	5/740	73/8135	0.8061	0.9901	0.9112	ALDH6A1/PLCB4/PIP4K2A/INPP5K/MTMR14	5
KEGG	hsa04978	Mineral absorption	4/740	60/8135	0.8079	0.9901	0.9112	CLCN2/MT1H/ATP1B3/STEAP2	4
KEGG	hsa05208	Chemical carcinogenesis - reactive oxygen species	17/740	223/8135	0.8128	0.9924	0.9133	CAT/ABL2/FOS/PLD1/VEGFA/RELA/SDHA/GSTO1/MGST1/GSTM3/COX6A1/EPHX2/NFKBIA/GSTT1/VDAC2/AKT3/NOX4	17
KEGG	hsa00061	Fatty acid biosynthesis	1/740	18/8135	0.8207	0.9946	0.9153	HSD17B8	1
KEGG	hsa00511	Other glycan degradation	1/740	18/8135	0.8207	0.9946	0.9153	MAN2B1	1
KEGG	hsa04213	Longevity regulating pathway - multiple species	4/740	62/8135	0.8279	0.9996	0.9199	CAT/PRKAA2/ADCY8/AKT3	4
KEGG	hsa03250	Viral life cycle - HIV-1	4/740	63/8135	0.8372	0.9999	0.9202	MX1/ELL2/MAP1B/SAMHD1	4
KEGG	hsa00980	Metabolism of xenobiotics by cytochrome P450	5/740	78/8135	0.8495	0.9999	0.9202	GSTO1/MGST1/GSTM3/GSTT1/ADH7	5
KEGG	hsa04721	Synaptic vesicle cycle	5/740	78/8135	0.8495	0.9999	0.9202	SLC6A2/TCIRG1/ATP6V0B/RAB3A/AP2B1	5
KEGG	hsa00670	One carbon pool by folate	1/740	20/8135	0.8519	0.9999	0.9202	MTHFD2L	1
KEGG	hsa00350	Tyrosine metabolism	2/740	36/8135	0.852	0.9999	0.9202	AOC2/ADH7	2
KEGG	hsa04114	Oocyte meiosis	9/740	131/8135	0.8539	0.9999	0.9202	AR/PPP3CA/PPP1CB/CALM3/CALM1/ANAPC2/ADCY8/CAMK2D/CDK2	9
KEGG	hsa04927	Cortisol synthesis and secretion	4/740	65/8135	0.8546	0.9999	0.9202	NR4A1/PLCB4/CACNA1D/ADCY8	4
KEGG	hsa04960	Aldosterone-regulated sodium reabsorption	2/740	37/8135	0.8626	0.9999	0.9202	PRKCA/ATP1B3	2
KEGG	hsa05204	Chemical carcinogenesis - DNA adducts	4/740	69/8135	0.8847	0.9999	0.9202	GSTO1/MGST1/GSTM3/GSTT1	4
KEGG	hsa05211	Renal cell carcinoma	4/740	69/8135	0.8847	0.9999	0.9202	VEGFA/ETS1/PAK1/AKT3	4
KEGG	hsa04614	Renin-angiotensin system	1/740	23/8135	0.8888	0.9999	0.9202	CMA1	1
KEGG	hsa00260	Glycine, serine and threonine metabolism	2/740	40/8135	0.8903	0.9999	0.9202	AOC2/PSPH	2
KEGG	hsa00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	1/740	24/8135	0.899	0.9999	0.9202	HS6ST1	1
KEGG	hsa04932	Non-alcoholic fatty liver disease	10/740	155/8135	0.9082	0.9999	0.9202	SOCS3/PRKAA2/FOS/RELA/IL1B/SDHA/COX6A1/PPARG/AKT3/RXRA	10
KEGG	hsa04914	Progesterone-mediated oocyte maturation	6/740	102/8135	0.9122	0.9999	0.9202	PDE3B/ANAPC2/ADCY8/HSP90AB1/AKT3/CDK2	6
KEGG	hsa04975	Fat digestion and absorption	2/740	43/8135	0.9128	0.9999	0.9202	PLA2G2C/PLA2G2A	2
KEGG	hsa04950	Maturity onset diabetes of the young	1/740	26/8135	0.9166	0.9999	0.9202	MAFA	1
KEGG	hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	1/740	27/8135	0.9242	0.9999	0.9202	A4GALT	1
KEGG	hsa04966	Collecting duct acid secretion	1/740	27/8135	0.9242	0.9999	0.9202	TCIRG1	1
KEGG	hsa04144	Endocytosis	17/740	251/8135	0.9259	0.9999	0.9202	HLA-B/FOLR1/HLA-A/PML/PLD1/AGAP5/HLA-F/CAPZB/EPS15L1/CBL/DAB2/CYTH2/TGFBR1/CHMP1B/NEDD4/AP2B1/RAB11FIP3	17
KEGG	hsa05100	Bacterial invasion of epithelial cells	4/740	77/8135	0.9289	0.9999	0.9202	SHC1/ITGA5/CBL/CTNNA2	4
KEGG	hsa03050	Proteasome	2/740	46/8135	0.9309	0.9999	0.9202	PSMA4/PSMA6	2
KEGG	hsa04723	Retrograde endocannabinoid signaling	9/740	148/8135	0.931	0.9999	0.9202	GRIA2/GNG7/PLCB4/GRIA3/CACNA1D/ABHD6/PRKCA/ADCY8/GABRE	9
KEGG	hsa05415	Diabetic cardiomyopathy	13/740	203/8135	0.9359	0.9999	0.9202	PLCB4/PPP1CB/RELA/SDHA/PRKCA/COX6A1/TGFBR1/VDAC2/RYR2/CMA1/AKT3/CAMK2D/PDK3	13
KEGG	hsa03420	Nucleotide excision repair	2/740	47/8135	0.936	0.9999	0.9202	ERCC1/CETN2	2
KEGG	hsa03013	Nucleocytoplasmic transport	6/740	108/8135	0.9363	0.9999	0.9202	EEF1A1/THOC1/POM121/IPO13/KPNA3/IPO4	6
KEGG	hsa05010	Alzheimer disease	27/740	384/8135	0.9416	0.9999	0.9202	PLCB4/PPP3CA/FZD6/CACNA1D/CALM3/APP/APH1A/AXIN2/RELA/CALM1/GRIN2D/IL1B/SDHA/APOE/COX6A1/ADAM10/CAPN1/PSMA4/VDAC2/PSMA6/FADD/AKT3/WIPI2/TUBB8/TUBB6/NOX4/FRAT2	27
KEGG	hsa05150	Staphylococcus aureus infection	5/740	96/8135	0.9448	0.9999	0.9202	CFI/KRT38/ICAM1/HLA-DMB/HLA-DPA1	5
KEGG	hsa04672	Intestinal immune network for IgA production	2/740	49/8135	0.9454	0.9999	0.9202	HLA-DMB/HLA-DPA1	2
KEGG	hsa04146	Peroxisome	4/740	82/8135	0.9482	0.9999	0.9202	CAT/MPV17L2/EPHX2/HSD17B4	4
KEGG	hsa04664	Fc epsilon RI signaling pathway	3/740	68/8135	0.9539	0.9999	0.9202	MAP2K6/PRKCA/AKT3	3
KEGG	hsa05016	Huntington disease	20/740	306/8135	0.9596	0.9999	0.9202	GRIA2/PLCB4/GRIA3/DLG4/DNAH6/DNAH3/SDHA/COX6A1/BBC3/PSMA4/VDAC2/PSMA6/PPARG/WIPI2/NRF1/TUBB8/AP2B1/TUBB6/DNALI1/MAP3K10	20
KEGG	hsa03020	RNA polymerase	1/740	34/8135	0.9612	0.9999	0.9202	POLR3B	1
KEGG	hsa00760	Nicotinate and nicotinamide metabolism	1/740	36/8135	0.968	0.9999	0.9202	NMNAT1	1
KEGG	hsa05014	Amyotrophic lateral sclerosis	24/740	364/8135	0.9681	0.9999	0.9202	GRIA2/CAT/UBQLN3/PPP3CA/DNAH6/SRSF7/POM121/HSPA5/OPTN/MAP2K6/DNAH3/GRIN2D/BCL2L1/SDHA/COX6A1/CHCHD10/PSMA4/PSMA6/UBQLN1/WIPI2/TUBB8/TUBB6/DNALI1/DAXX	24
KEGG	hsa05020	Prion disease	17/740	273/8135	0.9683	0.9999	0.9202	EGR1/C9/PPP3CA/C7/CACNA1D/HSPA5/GRIN2D/IL1B/SDHA/COX6A1/PSMA4/VDAC2/RYR2/PSMA6/CCL5/TUBB8/TUBB6	17
KEGG	hsa04216	Ferroptosis	1/740	41/8135	0.9802	0.9999	0.9202	VDAC2	1
KEGG	hsa03015	mRNA surveillance pathway	4/740	97/8135	0.9808	0.9999	0.9202	PPP1CB/SYMPK/PABPC1L/CSTF2T	4
KEGG	hsa04666	Fc gamma R-mediated phagocytosis	4/740	97/8135	0.9808	0.9999	0.9202	PLD1/PRKCA/PAK1/AKT3	4
KEGG	hsa00860	Porphyrin metabolism	1/740	43/8135	0.9836	0.9999	0.9202	FECH	1
KEGG	hsa03022	Basal transcription factors	1/740	45/8135	0.9865	0.9999	0.9202	GTF2A1L	1
KEGG	hsa05322	Systemic lupus erythematosus	6/740	136/8135	0.9877	0.9999	0.9202	C9/C7/HLA-DMB/HLA-DPA1/ACTN1/TRIM21	6
KEGG	hsa04080	Neuroactive ligand-receptor interaction	21/740	353/8135	0.9895	0.9999	0.9202	GRIA2/PTGER4/NTS/GRIA3/GAL/HTR2A/MC3R/EDN3/CHRNA6/GRIN2D/PTGFR/NMBR/HTR1B/GRIK3/PRLR/GABRE/F2R/TACR3/MLNR/S1PR3/PATE3	21
KEGG	hsa05034	Alcoholism	9/740	187/8135	0.9909	0.9999	0.9202	GNG7/PPP1CB/SHC1/HDAC5/CALM3/FOSB/CALM1/GRIN2D/PKIA	9
KEGG	hsa04613	Neutrophil extracellular trap formation	9/740	190/8135	0.9923	0.9999	0.9202	PLCB4/TLR8/SIGLEC9/TLR4/HDAC5/RELA/PRKCA/VDAC2/AKT3	9
KEGG	hsa00270	Cysteine and methionine metabolism	1/740	51/8135	0.9924	0.9999	0.9202	BHMT2	1
KEGG	hsa04913	Ovarian steroidogenesis	1/740	51/8135	0.9924	0.9999	0.9202	ADCY8	1
KEGG	hsa05012	Parkinson disease	14/740	266/8135	0.9933	0.9999	0.9202	CALM3/HSPA5/CALM1/BCL2L1/SDHA/COX6A1/RPS27A/PSMA4/VDAC2/PSMA6/TUBB8/TUBB6/DAXX/CAMK2D	14
KEGG	hsa00140	Steroid hormone biosynthesis	1/740	61/8135	0.9971	0.9999	0.9202	HSD17B8	1
KEGG	hsa00970	Aminoacyl-tRNA biosynthesis	1/740	66/8135	0.9982	0.9999	0.9202	PARS2	1
KEGG	hsa04714	Thermogenesis	10/740	232/8135	0.9984	0.9999	0.9202	PRKAA2/SLC25A20/PLIN1/CPT1C/RPS6/SDHA/ADCY8/ADCY10/COX6A1/PPARG	10
KEGG	hsa00830	Retinol metabolism	1/740	68/8135	0.9985	0.9999	0.9202	ADH7	1
KEGG	hsa00190	Oxidative phosphorylation	4/740	134/8135	0.9987	0.9999	0.9202	SDHA/COX6A1/TCIRG1/ATP6V0B	4
KEGG	hsa04740	Olfactory transduction	23/740	440/8135	0.9993	0.9999	0.9202	GNG7/OR2A4/OR10V1/OR56A3/CALM3/PDE1A/CALM1/OR1E1/OR2A25/OR52N4/OR4D10/OR4F21/OR52N2/NCALD/OR5B17/OR9G4/OR4S1/OR3A2/OR4D11/OR1A2/OR5H15/OR5AR1/CAMK2D	23
KEGG	hsa03008	Ribosome biogenesis in eukaryotes	2/740	109/8135	0.9997	0.9999	0.9202	TCOF1/RPP40	2
KEGG	hsa03040	Spliceosome	3/740	147/8135	0.9999	0.9999	0.9202	THOC1/SRSF7/SRSF6	3