ONTOLOGY ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count BP GO:0010822 positive regulation of mitochondrion organization 7/225 117/18670 0.0005432 0.5086 0.4904 CAMKK2/BOK/PLA2G6/VPS13D/USP36/MICALL2/CHCHD10 7 BP GO:0035967 cellular response to topologically incorrect protein 8/225 161/18670 0.0007609 0.5086 0.4904 HSPA2/SHC1/VCP/BOK/CUL3/EIF2S1/RNF5/RNF175 8 BP GO:0006750 glutathione biosynthetic process 3/225 17/18670 0.001037 0.5086 0.4904 CNDP2/GGT5/GCLC 3 BP GO:0019184 nonribosomal peptide biosynthetic process 3/225 19/18670 0.001451 0.5086 0.4904 CNDP2/GGT5/GCLC 3 BP GO:0030148 sphingolipid biosynthetic process 6/225 102/18670 0.001475 0.5086 0.4904 ST8SIA5/SPHK1/DEGS2/PLA2G6/ELOVL5/B3GALT4 6 BP GO:0090280 positive regulation of calcium ion import 3/225 21/18670 0.001957 0.5086 0.4904 GRM6/CALCR/STC1 3 BP GO:0071218 cellular response to misfolded protein 3/225 24/18670 0.0029 0.5086 0.4904 VCP/CUL3/RNF5 3 BP GO:0035966 response to topologically incorrect protein 8/225 199/18670 0.002911 0.5086 0.4904 HSPA2/SHC1/VCP/BOK/CUL3/EIF2S1/RNF5/RNF175 8 BP GO:0042398 cellular modified amino acid biosynthetic process 4/225 50/18670 0.003065 0.5086 0.4904 CNDP2/GGT5/GCLC/PLOD1 4 BP GO:0051788 response to misfolded protein 3/225 26/18670 0.003659 0.5086 0.4904 VCP/CUL3/RNF5 3 BP GO:0060074 synapse maturation 3/225 26/18670 0.003659 0.5086 0.4904 ANAPC2/ARHGEF15/PALM 3 BP GO:0009895 negative regulation of catabolic process 10/225 308/18670 0.004302 0.5086 0.4904 ROCK1/CST3/DAZL/TIMP4/NMNAT1/QSOX1/INS/GRIN2A/USP36/RNF5 10 BP GO:0006515 protein quality control for misfolded or incompletely synthesized proteins 3/225 28/18670 0.00453 0.5086 0.4904 VCP/CUL3/RNF5 3 BP GO:0006749 glutathione metabolic process 4/225 56/18670 0.004621 0.5086 0.4904 CNDP2/GGT5/GCLC/GSTA1 4 BP GO:0031330 negative regulation of cellular catabolic process 9/225 264/18670 0.004854 0.5086 0.4904 ROCK1/CST3/DAZL/TIMP4/NMNAT1/QSOX1/INS/USP36/RNF5 9 BP GO:0006906 vesicle fusion 5/225 94/18670 0.005601 0.5086 0.4904 SYT4/TMEM175/SPHK1/PRRT2/STX1B 5 BP GO:0006790 sulfur compound metabolic process 11/225 372/18670 0.005629 0.5086 0.4904 SLC25A10/GADL1/STAT5A/CNDP2/SP1/ACSM2A/GGT5/ELOVL5/GCLC/GSTA1/NDST4 11 BP GO:0022406 membrane docking 7/225 178/18670 0.005908 0.5086 0.4904 ROCK1/TUBB/CEP70/CEP131/STX1B/NINL/RAB15 7 BP GO:0031338 regulation of vesicle fusion 3/225 31/18670 0.006053 0.5086 0.4904 SYT4/SPHK1/PRRT2 3 BP GO:0007135 meiosis II 2/225 10/18670 0.006105 0.5086 0.4904 BUB1/DAZL 2 BP GO:0042891 antibiotic transport 2/225 10/18670 0.006105 0.5086 0.4904 SLC13A5/SLC26A6 2 BP GO:0061983 meiosis II cell cycle process 2/225 10/18670 0.006105 0.5086 0.4904 BUB1/DAZL 2 BP GO:0071104 response to interleukin-9 2/225 10/18670 0.006105 0.5086 0.4904 IL9R/STAT5A 2 BP GO:0046513 ceramide biosynthetic process 4/225 61/18670 0.006267 0.5086 0.4904 SPHK1/DEGS2/PLA2G6/B3GALT4 4 BP GO:0043270 positive regulation of ion transport 9/225 275/18670 0.006298 0.5086 0.4904 HSPA2/SYT4/GRM6/PLA2G6/TNFSF11/F2RL3/CHCHD10/CALCR/STC1 9 BP GO:0010821 regulation of mitochondrion organization 7/225 182/18670 0.006649 0.5086 0.4904 CAMKK2/BOK/PLA2G6/VPS13D/USP36/MICALL2/CHCHD10 7 BP GO:0042176 regulation of protein catabolic process 11/225 381/18670 0.006693 0.5086 0.4904 ROCK1/CST3/TIMP4/VCP/BARD1/INS/IL33/PSMC1/GRIN2A/DVL1/GCLC 11 BP GO:0035418 protein localization to synapse 4/225 63/18670 0.007022 0.5086 0.4904 GRIN2A/DVL1/STX1B/RAPSN 4 BP GO:0034620 cellular response to unfolded protein 6/225 140/18670 0.007058 0.5086 0.4904 HSPA2/SHC1/VCP/BOK/EIF2S1/RNF175 6 BP GO:0090174 organelle membrane fusion 5/225 100/18670 0.007251 0.5086 0.4904 SYT4/TMEM175/SPHK1/PRRT2/STX1B 5 BP GO:0031915 positive regulation of synaptic plasticity 2/225 11/18670 0.007403 0.5086 0.4904 ADCY8/ANAPC2 2 BP GO:0046579 positive regulation of Ras protein signal transduction 4/225 64/18670 0.00742 0.5086 0.4904 SHC1/RAPGEF1/FGF10/F2RL3 4 BP GO:0046467 membrane lipid biosynthetic process 6/225 142/18670 0.007547 0.5086 0.4904 ST8SIA5/SPHK1/DEGS2/PLA2G6/ELOVL5/B3GALT4 6 BP GO:1903008 organelle disassembly 5/225 101/18670 0.007556 0.5086 0.4904 CAMKK2/VCP/ATG12/VPS13D/USP36 5 BP GO:0032892 positive regulation of organic acid transport 3/225 34/18670 0.007848 0.5086 0.4904 SYT4/PLA2G6/TNFSF11 3 BP GO:0051783 regulation of nuclear division 7/225 188/18670 0.007887 0.5086 0.4904 BUB1/PKMYT1/DAZL/SPHK1/INS/CUL3/TPR 7 BP GO:0044262 cellular carbohydrate metabolic process 9/225 286/18670 0.008052 0.5086 0.4904 NAGK/INS/SLC35B4/DUSP12/MOGAT1/TFF3/MIOX/NDST4/PCDH12 9 BP GO:0051785 positive regulation of nuclear division 4/225 66/18670 0.008262 0.5086 0.4904 DAZL/SPHK1/INS/CUL3 4 BP GO:1903539 protein localization to postsynaptic membrane 3/225 35/18670 0.008509 0.5086 0.4904 GRIN2A/STX1B/RAPSN 3 BP GO:1901800 positive regulation of proteasomal protein catabolic process 5/225 104/18670 0.008523 0.5086 0.4904 VCP/IL33/PSMC1/DVL1/GCLC 5 BP GO:0044272 sulfur compound biosynthetic process 7/225 192/18670 0.008803 0.5086 0.4904 CNDP2/SP1/GGT5/ELOVL5/GCLC/GSTA1/NDST4 7 BP GO:0038110 interleukin-2-mediated signaling pathway 2/225 12/18670 0.008813 0.5086 0.4904 SHC1/STAT5A 2 BP GO:0071712 ER-associated misfolded protein catabolic process 2/225 12/18670 0.008813 0.5086 0.4904 VCP/RNF5 2 BP GO:0043524 negative regulation of neuron apoptotic process 6/225 147/18670 0.008876 0.5086 0.4904 ROCK1/NMNAT1/BOK/CNTFR/EN1/GCLC 6 BP GO:0050905 neuromuscular process 5/225 107/18670 0.009573 0.5086 0.4904 HOXA1/NKX6-2/GRIN2A/DVL1/PRRT2 5 BP GO:0030004 cellular monovalent inorganic cation homeostasis 5/225 108/18670 0.009942 0.5086 0.4904 ATP4A/TMEM175/SLC9A8/SLC26A6/SLC9A3 5 BP GO:0035723 interleukin-15-mediated signaling pathway 2/225 13/18670 0.01033 0.5086 0.4904 SHC1/STAT5A 2 BP GO:0071350 cellular response to interleukin-15 2/225 13/18670 0.01033 0.5086 0.4904 SHC1/STAT5A 2 BP GO:0071352 cellular response to interleukin-2 2/225 13/18670 0.01033 0.5086 0.4904 SHC1/STAT5A 2 BP GO:0098703 calcium ion import across plasma membrane 2/225 13/18670 0.01033 0.5086 0.4904 FAM155B/CALCR 2 BP GO:0051057 positive regulation of small GTPase mediated signal transduction 4/225 71/18670 0.01063 0.5086 0.4904 SHC1/RAPGEF1/FGF10/F2RL3 4 BP GO:0006575 cellular modified amino acid metabolic process 7/225 202/18670 0.01143 0.5086 0.4904 GGH/CNDP2/GGT5/GCLC/PLOD1/GSTA1/TYMS 7 BP GO:0070669 response to interleukin-2 2/225 14/18670 0.01196 0.5086 0.4904 SHC1/STAT5A 2 BP GO:0070672 response to interleukin-15 2/225 14/18670 0.01196 0.5086 0.4904 SHC1/STAT5A 2 BP GO:0090128 regulation of synapse maturation 2/225 14/18670 0.01196 0.5086 0.4904 ANAPC2/ARHGEF15 2 BP GO:1902656 calcium ion import into cytosol 2/225 14/18670 0.01196 0.5086 0.4904 FAM155B/CALCR 2 BP GO:0045446 endothelial cell differentiation 5/225 114/18670 0.01236 0.5086 0.4904 ROCK1/RAPGEF1/ATOH8/STC1/ACVRL1 5 BP GO:0031331 positive regulation of cellular catabolic process 10/225 361/18670 0.01247 0.5086 0.4904 ROCK1/CAMKK2/VCP/INS/IL33/NPRL2/PSMC1/DVL1/GCLC/VPS13D 10 BP GO:0006665 sphingolipid metabolic process 6/225 159/18670 0.01274 0.5086 0.4904 ST8SIA5/SPHK1/DEGS2/PLA2G6/ELOVL5/B3GALT4 6 BP GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 11/225 419/18670 0.01303 0.5086 0.4904 VCP/ERLIN2/CUL3/ANAPC2/IL33/PSMC1/DVL1/GCLC/RMND5B/RNF5/RNF175 11 BP GO:0090279 regulation of calcium ion import 3/225 41/18670 0.01315 0.5086 0.4904 GRM6/CALCR/STC1 3 BP GO:1901215 negative regulation of neuron death 7/225 208/18670 0.01326 0.5086 0.4904 ROCK1/NMNAT1/BOK/CNTFR/EN1/PSMC1/GCLC 7 BP GO:0000422 autophagy of mitochondrion 4/225 76/18670 0.01341 0.5086 0.4904 CAMKK2/ATG12/VPS13D/USP36 4 BP GO:0048844 artery morphogenesis 4/225 76/18670 0.01341 0.5086 0.4904 HOXA1/PRRX1/ACVRL1/AKT3 4 BP GO:0061726 mitochondrion disassembly 4/225 76/18670 0.01341 0.5086 0.4904 CAMKK2/ATG12/VPS13D/USP36 4 BP GO:0009896 positive regulation of catabolic process 11/225 423/18670 0.0139 0.5086 0.4904 ROCK1/CAMKK2/VCP/BARD1/INS/IL33/NPRL2/PSMC1/DVL1/GCLC/VPS13D 11 BP GO:0043523 regulation of neuron apoptotic process 7/225 210/18670 0.01391 0.5086 0.4904 ROCK1/NMNAT1/BOK/CNTFR/EN1/GCLC/RAPSN 7 BP GO:1901214 regulation of neuron death 9/225 313/18670 0.01393 0.5086 0.4904 ROCK1/NMNAT1/BOK/CNTFR/EIF2S1/EN1/PSMC1/GCLC/RAPSN 9 BP GO:0006509 membrane protein ectodomain proteolysis 3/225 42/18670 0.01404 0.5086 0.4904 ROCK1/APH1A/TIMP4 3 BP GO:1903146 regulation of autophagy of mitochondrion 3/225 42/18670 0.01404 0.5086 0.4904 CAMKK2/VPS13D/USP36 3 BP GO:0045931 positive regulation of mitotic cell cycle 6/225 163/18670 0.01425 0.5086 0.4904 HSPA2/SPHK1/INS/CUL3/TPR/FGF10 6 BP GO:0070838 divalent metal ion transport 12/225 483/18670 0.0145 0.5086 0.4904 HSPA2/GRM6/SLC30A7/SLC39A11/PLA2G6/CLCA1/GRIN2A/SLC35G1/FAM155B/F2RL3/CALCR/STC1 12 BP GO:0030433 ubiquitin-dependent ERAD pathway 4/225 78/18670 0.01463 0.5086 0.4904 VCP/ERLIN2/RNF5/RNF175 4 BP GO:0007088 regulation of mitotic nuclear division 6/225 164/18670 0.01465 0.5086 0.4904 BUB1/PKMYT1/SPHK1/INS/CUL3/TPR 6 BP GO:0032924 activin receptor signaling pathway 3/225 43/18670 0.01496 0.5086 0.4904 FGF10/ACVRL1/CFC1 3 BP GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process 5/225 120/18670 0.01515 0.5086 0.4904 VCP/IL33/PSMC1/DVL1/GCLC 5 BP GO:0032305 positive regulation of icosanoid secretion 2/225 16/18670 0.01553 0.5086 0.4904 PLA2G6/TNFSF11 2 BP GO:0046519 sphingoid metabolic process 2/225 16/18670 0.01553 0.5086 0.4904 SPHK1/DEGS2 2 BP GO:0048791 calcium ion-regulated exocytosis of neurotransmitter 2/225 16/18670 0.01553 0.5086 0.4904 SYT4/STX1B 2 BP GO:0090153 regulation of sphingolipid biosynthetic process 2/225 16/18670 0.01553 0.5086 0.4904 SPHK1/PLA2G6 2 BP GO:1902358 sulfate transmembrane transport 2/225 16/18670 0.01553 0.5086 0.4904 SLC25A10/SLC26A6 2 BP GO:1905038 regulation of membrane lipid metabolic process 2/225 16/18670 0.01553 0.5086 0.4904 SPHK1/PLA2G6 2 BP GO:2000303 regulation of ceramide biosynthetic process 2/225 16/18670 0.01553 0.5086 0.4904 SPHK1/PLA2G6 2 BP GO:0030968 endoplasmic reticulum unfolded protein response 5/225 121/18670 0.01566 0.5086 0.4904 SHC1/VCP/BOK/EIF2S1/RNF175 5 BP GO:0072511 divalent inorganic cation transport 12/225 489/18670 0.01582 0.5086 0.4904 HSPA2/GRM6/SLC30A7/SLC39A11/PLA2G6/CLCA1/GRIN2A/SLC35G1/FAM155B/F2RL3/CALCR/STC1 12 BP GO:0045601 regulation of endothelial cell differentiation 3/225 44/18670 0.01591 0.5086 0.4904 ROCK1/ATOH8/ACVRL1 3 BP GO:0070509 calcium ion import 4/225 80/18670 0.01593 0.5086 0.4904 GRM6/FAM155B/CALCR/STC1 4 BP GO:0050806 positive regulation of synaptic transmission 6/225 168/18670 0.01631 0.5086 0.4904 ADCY8/INS/GRIN2A/DVL1/STX1B/RAPSN 6 BP GO:0071804 cellular potassium ion transport 7/225 217/18670 0.01637 0.5086 0.4904 KCNK7/ATP4A/TMEM175/DPP6/HCN3/SLC9A8/SLC9A3 7 BP GO:0071805 potassium ion transmembrane transport 7/225 217/18670 0.01637 0.5086 0.4904 KCNK7/ATP4A/TMEM175/DPP6/HCN3/SLC9A8/SLC9A3 7 BP GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 4/225 81/18670 0.0166 0.5086 0.4904 VCP/IL33/DVL1/GCLC 4 BP GO:0051928 positive regulation of calcium ion transport 5/225 123/18670 0.01669 0.5086 0.4904 HSPA2/GRM6/F2RL3/CALCR/STC1 5 BP GO:0140056 organelle localization by membrane tethering 6/225 169/18670 0.01675 0.5086 0.4904 TUBB/CEP70/CEP131/STX1B/NINL/RAB15 6 BP GO:0001974 blood vessel remodeling 3/225 45/18670 0.0169 0.5086 0.4904 CST3/FGF10/ACVRL1 3 BP GO:0050804 modulation of chemical synaptic transmission 11/225 436/18670 0.01702 0.5086 0.4904 SYT4/ADCY8/GRM6/INS/ANAPC2/PLA2G6/GRIN2A/DVL1/PRRT2/STX1B/RAPSN 11 BP GO:0008637 apoptotic mitochondrial changes 5/225 124/18670 0.01723 0.5086 0.4904 BOK/SLC25A4/PLA2G6/GCLC/CHCHD10 5 BP GO:0046717 acid secretion 5/225 124/18670 0.01723 0.5086 0.4904 SYT4/PLA2G6/TNFSF11/SLC26A6/SLC51A 5 BP GO:0048284 organelle fusion 5/225 124/18670 0.01723 0.5086 0.4904 SYT4/TMEM175/SPHK1/PRRT2/STX1B 5 BP GO:0099177 regulation of trans-synaptic signaling 11/225 437/18670 0.01728 0.5086 0.4904 SYT4/ADCY8/GRM6/INS/ANAPC2/PLA2G6/GRIN2A/DVL1/PRRT2/STX1B/RAPSN 11 BP GO:0008272 sulfate transport 2/225 17/18670 0.01746 0.5086 0.4904 SLC25A10/SLC26A6 2 BP GO:0030322 stabilization of membrane potential 2/225 17/18670 0.01746 0.5086 0.4904 KCNK7/CHCHD10 2 BP GO:0043651 linoleic acid metabolic process 2/225 17/18670 0.01746 0.5086 0.4904 ELOVL5/GSTA1 2 BP GO:0061298 retina vasculature development in camera-type eye 2/225 17/18670 0.01746 0.5086 0.4904 ARHGEF15/ACVRL1 2 BP GO:0006984 ER-nucleus signaling pathway 3/225 46/18670 0.01792 0.5086 0.4904 ERLIN2/BOK/EIF2S1 3 BP GO:0098659 inorganic cation import across plasma membrane 4/225 83/18670 0.018 0.5086 0.4904 ATP4A/FAM155B/CALCR/SLC9A3 4 BP GO:0099587 inorganic ion import across plasma membrane 4/225 83/18670 0.018 0.5086 0.4904 ATP4A/FAM155B/CALCR/SLC9A3 4 BP GO:0051453 regulation of intracellular pH 4/225 84/18670 0.01872 0.5086 0.4904 TMEM175/SLC9A8/SLC26A6/SLC9A3 4 BP GO:1901990 regulation of mitotic cell cycle phase transition 11/225 444/18670 0.01919 0.5086 0.4904 HSPA2/BUB1/TUBB/CUL3/ANAPC2/PSMC1/CEP70/CEP131/TPR/NINL/FGF10 11 BP GO:0002098 tRNA wobble uridine modification 2/225 18/18670 0.01949 0.5086 0.4904 ELP4/ALKBH8 2 BP GO:0060546 negative regulation of necroptotic process 2/225 18/18670 0.01949 0.5086 0.4904 BOK/SLC25A4 2 BP GO:2000193 positive regulation of fatty acid transport 2/225 18/18670 0.01949 0.5086 0.4904 PLA2G6/TNFSF11 2 BP GO:0006986 response to unfolded protein 6/225 176/18670 0.02003 0.5086 0.4904 HSPA2/SHC1/VCP/BOK/EIF2S1/RNF175 6 BP GO:0009408 response to heat 6/225 176/18670 0.02003 0.5086 0.4904 HSPA2/VCP/EIF2S1/CRNN/GCLC/TPR 6 BP GO:0007595 lactation 3/225 48/18670 0.02007 0.5086 0.4904 STAT5A/CSN3/OAS2 3 BP GO:0050803 regulation of synapse structure or activity 7/225 227/18670 0.02041 0.5086 0.4904 VCP/TUBB/INS/ANAPC2/ARHGEF15/STX1B/RAPSN 7 BP GO:0009060 aerobic respiration 4/225 87/18670 0.02101 0.5086 0.4904 ACO2/VCP/IDH3G/UQCRC1 4 BP GO:0032303 regulation of icosanoid secretion 2/225 19/18670 0.02161 0.5086 0.4904 PLA2G6/TNFSF11 2 BP GO:0042693 muscle cell fate commitment 2/225 19/18670 0.02161 0.5086 0.4904 MYL2/FGF10 2 BP GO:0045947 negative regulation of translational initiation 2/225 19/18670 0.02161 0.5086 0.4904 EIF2S1/TPR 2 BP GO:1903540 establishment of protein localization to postsynaptic membrane 2/225 19/18670 0.02161 0.5086 0.4904 STX1B/RAPSN 2 BP GO:0003158 endothelium development 5/225 132/18670 0.02193 0.5086 0.4904 ROCK1/RAPGEF1/ATOH8/STC1/ACVRL1 5 BP GO:0042177 negative regulation of protein catabolic process 5/225 132/18670 0.02193 0.5086 0.4904 ROCK1/CST3/TIMP4/INS/GRIN2A 5 BP GO:0021700 developmental maturation 8/225 284/18670 0.02215 0.5086 0.4904 SYT4/DAZL/ANAPC2/SLC26A6/ARHGEF15/ACVRL1/TYMS/PALM 8 BP GO:1903793 positive regulation of anion transport 3/225 50/18670 0.02235 0.5086 0.4904 SYT4/PLA2G6/TNFSF11 3 BP GO:0015980 energy derivation by oxidation of organic compounds 8/225 285/18670 0.02256 0.5086 0.4904 NDUFB8/ACO2/VCP/INS/IDH3G/UQCRC1/NOA1/PCDH12 8 BP GO:0034976 response to endoplasmic reticulum stress 8/225 285/18670 0.02256 0.5086 0.4904 SHC1/VCP/ERLIN2/BOK/EIF2S1/PLA2G6/RNF5/RNF175 8 BP GO:0006094 gluconeogenesis 4/225 89/18670 0.02263 0.5086 0.4904 SLC25A10/ALDOC/INS/SLC35B4 4 BP GO:0030641 regulation of cellular pH 4/225 90/18670 0.02346 0.5086 0.4904 TMEM175/SLC9A8/SLC26A6/SLC9A3 4 BP GO:0030071 regulation of mitotic metaphase/anaphase transition 3/225 51/18670 0.02354 0.5086 0.4904 BUB1/CUL3/TPR 3 BP GO:0046823 negative regulation of nucleocytoplasmic transport 2/225 20/18670 0.02382 0.5086 0.4904 BARD1/TPR 2 BP GO:0070987 error-free translesion synthesis 2/225 20/18670 0.02382 0.5086 0.4904 VCP/RFC5 2 BP GO:1903599 positive regulation of autophagy of mitochondrion 2/225 20/18670 0.02382 0.5086 0.4904 CAMKK2/VPS13D 2 BP GO:0006732 coenzyme metabolic process 10/225 403/18670 0.02471 0.5086 0.4904 ALDOC/NMNAT1/VCP/GGH/INS/ACSM2A/ELOVL5/GCLC/TPR/TYMS 10 BP GO:0006301 postreplication repair 3/225 52/18670 0.02476 0.5086 0.4904 NSMCE1/VCP/RFC5 3 BP GO:0006672 ceramide metabolic process 4/225 92/18670 0.02519 0.5086 0.4904 SPHK1/DEGS2/PLA2G6/B3GALT4 4 BP GO:0019319 hexose biosynthetic process 4/225 92/18670 0.02519 0.5086 0.4904 SLC25A10/ALDOC/INS/SLC35B4 4 BP GO:0070997 neuron death 9/225 348/18670 0.02564 0.5086 0.4904 ROCK1/NMNAT1/BOK/CNTFR/EIF2S1/EN1/PSMC1/GCLC/RAPSN 9 BP GO:0048167 regulation of synaptic plasticity 6/225 187/18670 0.02602 0.5086 0.4904 SYT4/ADCY8/INS/ANAPC2/GRIN2A/PRRT2 6 BP GO:0045840 positive regulation of mitotic nuclear division 3/225 53/18670 0.02602 0.5086 0.4904 SPHK1/INS/CUL3 3 BP GO:0071320 cellular response to cAMP 3/225 53/18670 0.02602 0.5086 0.4904 RAPGEF1/SLC26A6/STC1 3 BP GO:1902099 regulation of metaphase/anaphase transition of cell cycle 3/225 53/18670 0.02602 0.5086 0.4904 BUB1/CUL3/TPR 3 BP GO:0007589 body fluid secretion 4/225 93/18670 0.02608 0.5086 0.4904 STAT5A/CSN3/FGF10/OAS2 4 BP GO:0051402 neuron apoptotic process 7/225 239/18670 0.02612 0.5086 0.4904 ROCK1/NMNAT1/BOK/CNTFR/EN1/GCLC/RAPSN 7 BP GO:0036499 PERK-mediated unfolded protein response 2/225 21/18670 0.02612 0.5086 0.4904 BOK/EIF2S1 2 BP GO:0051900 regulation of mitochondrial depolarization 2/225 21/18670 0.02612 0.5086 0.4904 BOK/GCLC 2 BP GO:0140058 neuron projection arborization 2/225 21/18670 0.02612 0.5086 0.4904 ROCK1/DVL1 2 BP GO:1900273 positive regulation of long-term synaptic potentiation 2/225 21/18670 0.02612 0.5086 0.4904 ADCY8/INS 2 BP GO:0050808 synapse organization 10/225 408/18670 0.02659 0.5086 0.4904 VCP/TUBB/INS/ANAPC2/DVL1/NDRG1/ARHGEF15/RAPSN/CHCHD10/PALM 10 BP GO:0006813 potassium ion transport 7/225 240/18670 0.02664 0.5086 0.4904 KCNK7/ATP4A/TMEM175/DPP6/HCN3/SLC9A8/SLC9A3 7 BP GO:0007091 metaphase/anaphase transition of mitotic cell cycle 3/225 54/18670 0.02731 0.5086 0.4904 BUB1/CUL3/TPR 3 BP GO:1903364 positive regulation of cellular protein catabolic process 5/225 140/18670 0.0274 0.5086 0.4904 VCP/IL33/PSMC1/DVL1/GCLC 5 BP GO:0044070 regulation of anion transport 4/225 95/18670 0.02792 0.5086 0.4904 SYT4/PLA2G6/TNFSF11/STC1 4 BP GO:0097711 ciliary basal body-plasma membrane docking 4/225 95/18670 0.02792 0.5086 0.4904 TUBB/CEP70/CEP131/NINL 4 BP GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process 4/225 95/18670 0.02792 0.5086 0.4904 VCP/IL33/DVL1/GCLC 4 BP GO:0055074 calcium ion homeostasis 11/225 471/18670 0.02803 0.5086 0.4904 ADCY8/BOK/PLA2G6/HCRTR2/GRIN2A/SLC35G1/TNFSF11/FAM155B/F2RL3/CALCR/STC1 11 BP GO:0002097 tRNA wobble base modification 2/225 22/18670 0.02851 0.5086 0.4904 ELP4/ALKBH8 2 BP GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane 2/225 22/18670 0.02851 0.5086 0.4904 PRRT2/STX1B 2 BP GO:0032069 regulation of nuclease activity 2/225 22/18670 0.02851 0.5086 0.4904 TCEA1/OAS2 2 BP GO:0034311 diol metabolic process 2/225 22/18670 0.02851 0.5086 0.4904 SPHK1/DEGS2 2 BP GO:0060547 negative regulation of necrotic cell death 2/225 22/18670 0.02851 0.5086 0.4904 BOK/SLC25A4 2 BP GO:0006835 dicarboxylic acid transport 4/225 96/18670 0.02887 0.5086 0.4904 SLC25A10/SYT4/SLC13A5/SLC26A6 4 BP GO:0090277 positive regulation of peptide hormone secretion 4/225 96/18670 0.02887 0.5086 0.4904 ADCY8/INS/PLA2G6/TNFSF11 4 BP GO:0051480 regulation of cytosolic calcium ion concentration 9/225 357/18670 0.02954 0.5086 0.4904 ADCY8/BOK/PLA2G6/HCRTR2/GRIN2A/SLC35G1/FAM155B/F2RL3/CALCR 9 BP GO:0030879 mammary gland development 5/225 143/18670 0.02966 0.5086 0.4904 STAT5A/TNFSF11/CSN3/FGF10/OAS2 5 BP GO:0035296 regulation of tube diameter 5/225 143/18670 0.02966 0.5086 0.4904 ROCK1/INS/ACTA2/PLA2G6/GCLC 5 BP GO:0050880 regulation of blood vessel size 5/225 143/18670 0.02966 0.5086 0.4904 ROCK1/INS/ACTA2/PLA2G6/GCLC 5 BP GO:0097746 regulation of blood vessel diameter 5/225 143/18670 0.02966 0.5086 0.4904 ROCK1/INS/ACTA2/PLA2G6/GCLC 5 BP GO:0045333 cellular respiration 6/225 193/18670 0.02974 0.5086 0.4904 NDUFB8/ACO2/VCP/IDH3G/UQCRC1/NOA1 6 BP GO:0044784 metaphase/anaphase transition of cell cycle 3/225 56/18670 0.03 0.5086 0.4904 BUB1/CUL3/TPR 3 BP GO:0010498 proteasomal protein catabolic process 11/225 477/18670 0.03034 0.5086 0.4904 VCP/ERLIN2/CUL3/ANAPC2/IL33/PSMC1/DVL1/GCLC/RMND5B/RNF5/RNF175 11 BP GO:0035150 regulation of tube size 5/225 144/18670 0.03043 0.5086 0.4904 ROCK1/INS/ACTA2/PLA2G6/GCLC 5 BP GO:0000086 G2/M transition of mitotic cell cycle 7/225 247/18670 0.03048 0.5086 0.4904 HSPA2/PKMYT1/TUBB/PSMC1/CEP70/CEP131/NINL 7 BP GO:0006885 regulation of pH 4/225 98/18670 0.03082 0.5086 0.4904 TMEM175/SLC9A8/SLC26A6/SLC9A3 4 BP GO:0030038 contractile actin filament bundle assembly 4/225 98/18670 0.03082 0.5086 0.4904 FHOD1/ROCK1/CUL3/ARHGEF15 4 BP GO:0042472 inner ear morphogenesis 4/225 98/18670 0.03082 0.5086 0.4904 HOXA1/PRRX1/DVL1/FGF10 4 BP GO:0043149 stress fiber assembly 4/225 98/18670 0.03082 0.5086 0.4904 FHOD1/ROCK1/CUL3/ARHGEF15 4 BP GO:0046364 monosaccharide biosynthetic process 4/225 98/18670 0.03082 0.5086 0.4904 SLC25A10/ALDOC/INS/SLC35B4 4 BP GO:0015740 C4-dicarboxylate transport 2/225 23/18670 0.03098 0.5086 0.4904 SLC25A10/SLC13A5 2 BP GO:0032753 positive regulation of interleukin-4 production 2/225 23/18670 0.03098 0.5086 0.4904 SASH3/IL33 2 BP GO:0051043 regulation of membrane protein ectodomain proteolysis 2/225 23/18670 0.03098 0.5086 0.4904 ROCK1/TIMP4 2 BP GO:0051882 mitochondrial depolarization 2/225 23/18670 0.03098 0.5086 0.4904 BOK/GCLC 2 BP GO:0070841 inclusion body assembly 2/225 23/18670 0.03098 0.5086 0.4904 HSPA2/VCP 2 BP GO:0099500 vesicle fusion to plasma membrane 2/225 23/18670 0.03098 0.5086 0.4904 PRRT2/STX1B 2 BP GO:1901889 negative regulation of cell junction assembly 2/225 23/18670 0.03098 0.5086 0.4904 ROCK1/ACVRL1 2 BP GO:0010965 regulation of mitotic sister chromatid separation 3/225 57/18670 0.03139 0.5086 0.4904 BUB1/CUL3/TPR 3 BP GO:1901987 regulation of cell cycle phase transition 11/225 480/18670 0.03155 0.5086 0.4904 HSPA2/BUB1/TUBB/CUL3/ANAPC2/PSMC1/CEP70/CEP131/TPR/NINL/FGF10 11 BP GO:0010389 regulation of G2/M transition of mitotic cell cycle 6/225 196/18670 0.03173 0.5086 0.4904 HSPA2/TUBB/PSMC1/CEP70/CEP131/NINL 6 BP GO:0071897 DNA biosynthetic process 6/225 196/18670 0.03173 0.5086 0.4904 TINF2/VCP/RFC5/SPHK1/ACVRL1/TYMS 6 BP GO:0009141 nucleoside triphosphate metabolic process 9/225 362/18670 0.03187 0.5086 0.4904 ALDOC/NDUFB8/NMNAT1/VCP/INS/UQCRC1/TPR/CHCHD10/TYMS 9 BP GO:0046034 ATP metabolic process 8/225 305/18670 0.03198 0.5086 0.4904 ALDOC/NDUFB8/NMNAT1/VCP/INS/UQCRC1/TPR/CHCHD10 8 BP GO:0036503 ERAD pathway 4/225 100/18670 0.03285 0.5086 0.4904 VCP/ERLIN2/RNF5/RNF175 4 BP GO:0060840 artery development 4/225 100/18670 0.03285 0.5086 0.4904 HOXA1/PRRX1/ACVRL1/AKT3 4 BP GO:0046890 regulation of lipid biosynthetic process 6/225 198/18670 0.0331 0.5086 0.4904 ERLIN2/SPHK1/INS/SP1/PLA2G6/ELOVL5 6 BP GO:0045603 positive regulation of endothelial cell differentiation 2/225 24/18670 0.03353 0.5086 0.4904 ATOH8/ACVRL1 2 BP GO:0090103 cochlea morphogenesis 2/225 24/18670 0.03353 0.5086 0.4904 HOXA1/DVL1 2 BP GO:1903421 regulation of synaptic vesicle recycling 2/225 24/18670 0.03353 0.5086 0.4904 ROCK1/STX1B 2 BP GO:1905564 positive regulation of vascular endothelial cell proliferation 2/225 24/18670 0.03353 0.5086 0.4904 SP1/AKT3 2 BP GO:0043312 neutrophil degranulation 11/225 485/18670 0.03363 0.5086 0.4904 ALDOC/PPIE/ROCK1/CST3/AGA/VCP/GGH/TUBB/QSOX1/COMMD9/LAIR1 11 BP GO:0035148 tube formation 5/225 148/18670 0.03367 0.5086 0.4904 HOXA1/SALL4/ATOH8/DVL1/FGF10 5 BP GO:0031032 actomyosin structure organization 6/225 199/18670 0.0338 0.5086 0.4904 FHOD1/ROCK1/MYOZ2/CUL3/MYL2/ARHGEF15 6 BP GO:0006520 cellular amino acid metabolic process 9/225 366/18670 0.03383 0.5086 0.4904 FARS2/GADL1/INS/SDSL/PSMC1/GGT5/GCLC/PLOD1/NAGS 9 BP GO:0007631 feeding behavior 4/225 101/18670 0.03389 0.5086 0.4904 CNTFR/INS/EN1/HCRTR2 4 BP GO:0001836 release of cytochrome c from mitochondria 3/225 59/18670 0.03427 0.5086 0.4904 BOK/PLA2G6/CHCHD10 3 BP GO:0001885 endothelial cell development 3/225 59/18670 0.03427 0.5086 0.4904 ROCK1/RAPGEF1/STC1 3 BP GO:0032890 regulation of organic acid transport 3/225 59/18670 0.03427 0.5086 0.4904 SYT4/PLA2G6/TNFSF11 3 BP GO:0033619 membrane protein proteolysis 3/225 59/18670 0.03427 0.5086 0.4904 ROCK1/APH1A/TIMP4 3 BP GO:0002283 neutrophil activation involved in immune response 11/225 488/18670 0.03493 0.5158 0.4973 ALDOC/PPIE/ROCK1/CST3/AGA/VCP/GGH/TUBB/QSOX1/COMMD9/LAIR1 11 BP GO:1990778 protein localization to cell periphery 8/225 311/18670 0.03527 0.5183 0.4997 ROCK1/INS/DPP6/GRIN2A/STX1B/RAPSN/RAB15/PALM 8 CC GO:0034774 secretory granule lumen 11/232 321/19717 0.001535 0.2955 0.288 ALDOC/PPIE/ROCK1/AGA/VCP/GGH/TUBB/QSOX1/INS/ITIH3/COMMD9 11 CC GO:0060205 cytoplasmic vesicle lumen 11/232 338/19717 0.002299 0.2955 0.288 ALDOC/PPIE/ROCK1/AGA/VCP/GGH/TUBB/QSOX1/INS/ITIH3/COMMD9 11 CC GO:0031983 vesicle lumen 11/232 339/19717 0.002352 0.2955 0.288 ALDOC/PPIE/ROCK1/AGA/VCP/GGH/TUBB/QSOX1/INS/ITIH3/COMMD9 11 CC GO:1904724 tertiary granule lumen 4/232 55/19717 0.003983 0.3663 0.3569 ALDOC/CST3/GGH/QSOX1 4 CC GO:0045171 intercellular bridge 4/232 59/19717 0.005125 0.3663 0.3569 QSOX1/CDCA8/CEP131/NINL 4 CC GO:0036513 Derlin-1 retrotranslocation complex 2/232 10/19717 0.005829 0.3663 0.3569 VCP/RNF5 2 CC GO:0030133 transport vesicle 11/232 392/19717 0.006942 0.3739 0.3643 HLA-DQB2/SYT4/KDELR2/APH1A/DPYSL3/INS/IL33/GRIN2A/PRRT2/STX1B/RAB15 11 CC GO:0097449 astrocyte projection 2/232 12/19717 0.008418 0.3967 0.3866 SYT4/EIF2S1 2 CC GO:0010369 chromocenter 2/232 14/19717 0.01143 0.4111 0.4006 TINF2/CDCA8 2 CC GO:0070382 exocytic vesicle 7/232 207/19717 0.01149 0.4111 0.4006 SYT4/APH1A/DPYSL3/GRIN2A/PRRT2/STX1B/RAB15 7 CC GO:0042734 presynaptic membrane 6/232 161/19717 0.01212 0.4111 0.4006 ADCY8/GRM6/APH1A/GRIN2A/PRRT2/STX1B 6 CC GO:0001673 male germ cell nucleus 2/232 15/19717 0.01309 0.4111 0.4006 HSPA2/ACTL7A 2 CC GO:0042613 MHC class II protein complex 2/232 16/19717 0.01484 0.4232 0.4124 HLA-DQB2/HLA-DMA 2 CC GO:1904813 ficolin-1-rich granule lumen 5/232 124/19717 0.01572 0.4232 0.4124 ALDOC/PPIE/CST3/VCP/COMMD9 5 MF GO:0017025 TBP-class protein binding 3/222 22/17697 0.002515 0.5023 0.4925 TAF1B/PSMC1/CAND2 3 MF GO:0015297 antiporter activity 5/222 85/17697 0.00432 0.5023 0.4925 SLC25A10/SLC25A4/SLC9A8/SLC26A6/SLC9A3 5 MF GO:0099516 ion antiporter activity 4/222 58/17697 0.006024 0.5023 0.4925 SLC25A4/SLC9A8/SLC26A6/SLC9A3 4 MF GO:0015386 potassium:proton antiporter activity 2/222 11/17697 0.007997 0.5023 0.4925 SLC9A8/SLC9A3 2 MF GO:0005451 monovalent cation:proton antiporter activity 2/222 12/17697 0.009518 0.5023 0.4925 SLC9A8/SLC9A3 2 MF GO:0015385 sodium:proton antiporter activity 2/222 12/17697 0.009518 0.5023 0.4925 SLC9A8/SLC9A3 2 MF GO:0031005 filamin binding 2/222 13/17697 0.01116 0.5023 0.4925 DPYSL3/MICALL2 2 MF GO:0050662 coenzyme binding 9/222 291/17697 0.01141 0.5023 0.4925 ACADS/HSD11B2/GADL1/QSOX1/IDH3G/SDSL/FMO4/GCLC/PLOD1 9 MF GO:0005310 dicarboxylic acid transmembrane transporter activity 3/222 39/17697 0.01277 0.5023 0.4925 SLC25A10/SLC13A5/SLC26A6 3 MF GO:0015556 C4-dicarboxylate transmembrane transporter activity 2/222 14/17697 0.01291 0.5023 0.4925 SLC25A10/SLC13A5 2 MF GO:0008242 omega peptidase activity 2/222 15/17697 0.01477 0.5023 0.4925 GGH/GGT5 2 MF GO:0015079 potassium ion transmembrane transporter activity 6/222 159/17697 0.01523 0.5023 0.4925 KCNK7/ATP4A/TMEM175/HCN3/SLC9A8/SLC9A3 6 MF GO:0005159 insulin-like growth factor receptor binding 2/222 16/17697 0.01674 0.5023 0.4925 SHC1/INS 2 MF GO:0015116 sulfate transmembrane transporter activity 2/222 16/17697 0.01674 0.5023 0.4925 SLC25A10/SLC26A6 2 MF GO:0022821 potassium ion antiporter activity 2/222 16/17697 0.01674 0.5023 0.4925 SLC9A8/SLC9A3 2 MF GO:0022841 potassium ion leak channel activity 2/222 16/17697 0.01674 0.5023 0.4925 KCNK7/TMEM175 2 MF GO:0071837 HMG box domain binding 2/222 16/17697 0.01674 0.5023 0.4925 PRRX1/SP1 2