ONTOLOGY	ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	qvalue	geneID	Count
KEGG	hsa05168	Herpes simplex virus 1 infection	108/988	495/8135	2.72e-10	8.977e-08	8.075e-08	HLA-DRB1/ZNF718/ZNF7/ZNF805/ZNF441/HLA-DQA1/ZNF442/ZNF8/ZNF461/ZNF333/ZNF689/ZNF766/ZNF12/ZNF777/ZNF791/ZNF430/ZNF708/ZNF160/ZNF74/ZNF350/PIK3CA/ZNF212/ZNF404/FADD/ZNF175/ZNF829/ZNF211/DDX58/ZNF549/ZNF431/ZNF627/ZNF669/ITGA5/ZNF492/ZNF432/ZNF746/ZNF155/TSC1/ZNF568/OAS2/NFKBIA/ZNF790/ZNF180/ZNF530/HLA-E/ZNF331/RBAK/ZNF136/IRF7/ZNF570/ZNF250/TRAF3/SRSF1/ZNF324/TSC2/ZNF707/ZNF248/CASP9/ZNF596/ZNF460/ZNF510/ZNF736/ZNF543/ZNF43/ZNF792/MAP3K7/HLA-DMB/ZNF343/ZNF420/SRSF8/MTOR/ZNF282/PIK3CB/ZNF37A/BAK1/C5/ZNF317/ZNF415/ZNF256/ZNF773/HLA-DMA/ZNF567/SRSF2/ZNF41/EIF2B5/ZNF484/ZNF552/PIK3CD/SRSF3/ZNF597/ZNF846/SRSF5/IL12A/ZNF275/ZNF45/ZNF783/ZNF234/ZNF251/BCL2L1/TRAF6/SRSF4/ZNF3/PML/ZNF527/ZNF26/ZNF419/ZNF230/TAP1	108
KEGG	hsa04140	Autophagy - animal	34/988	141/8135	5.385e-05	0.008886	0.007993	SMCR8/NRBF2/CFLAR/ULK1/PIK3CA/AKT1S1/BNIP3/ATG14/RAF1/TSC1/MTMR14/UVRAG/PRKCQ/TP53INP2/ATG2B/TSC2/AMBRA1/ATG4D/MTMR3/MAP3K7/ATG16L2/MTOR/SQSTM1/PIK3CB/LAMP1/GABARAPL1/ATG2A/RB1CC1/RPS6KB2/PIK3CD/BCL2L1/TRAF6/RPTOR/ERN1	34
KEGG	hsa05132	Salmonella infection	50/988	249/8135	0.0001926	0.01947	0.01751	MYL5/ABI1/TUBA1A/PIK3CA/DCTN4/TNFRSF10B/FADD/FBXO22/PLEKHM2/M6PR/RAF1/EXOC7/NFKBIA/DNM2/MAP2K7/VPS18/TUBB6/TUBA4A/FYCO1/DYNC1LI2/MAP3K7/CASP7/PIK3CB/CASP1/TNFSF10/BAK1/RHOH/DYNLL1/WASL/GSDMD/TUBB4B/RHOG/ARPC1B/PIK3CD/MAP2K6/ELMO1/CTNNB1/PYCARD/DYNLT1/TRAF6/RAB9A/RILP/TCF7L2/CYTH4/DCTN6/TUBB2A/KLC1/DCTN5/MYL12A/ARHGEF26	50
KEGG	hsa05169	Epstein-Barr virus infection	42/988	202/8135	0.0002848	0.01947	0.01751	HLA-DRB1/NFKBIE/CDK4/HLA-DQA1/NCOR2/CIR1/PIK3CA/RELB/NFKB2/TNFAIP3/FADD/ISG15/DDX58/MAP3K14/OAS2/NFKBIA/HLA-E/IRF7/MAP2K7/CDKN1A/NFKBIB/TRAF3/HDAC2/CD247/CASP9/PSMD7/PSMD6/MAP3K7/HLA-DMB/PIK3CB/DDB2/BAK1/ENTPD1/HLA-DMA/RUNX3/CDKN1B/PIK3CD/MAP2K6/SKP2/TRAF6/PSMC2/TAP1	42
KEGG	hsa03040	Spliceosome	33/988	147/8135	0.0002949	0.01947	0.01751	TCERG1/HNRNPA1L2/XAB2/HSPA1L/BCAS2/SF3A2/SLU7/RBMX/SF3A1/DHX8/HSPA1A/CDC40/SNRPA1/SRSF1/CCDC12/LSM6/RBM17/RP9/PHF5A/SRSF8/SNRPB/SRSF2/PPIL1/SRSF3/SRSF5/TXNL4A/HSPA8/SRSF4/PUF60/BUD31/SRSF10/DHX16/RBM25	33
KEGG	hsa03030	DNA replication	12/988	36/8135	0.0007417	0.03508	0.03156	RNASEH1/PRIM1/RNASEH2A/MCM7/FEN1/RPA2/POLD2/RPA1/MCM2/POLE/RNASEH2C/RFC2	12
KEGG	hsa04210	Apoptosis	30/988	136/8135	0.0007442	0.03508	0.03156	ATF4/CFLAR/TUBA1A/PIK3CA/TNFRSF10B/FADD/ENDOG/MAP3K14/RAF1/NFKBIA/PMAIP1/CASP6/TUBA4A/CTSW/CASP9/CASP7/PIK3CB/CTSF/TNFSF10/BAK1/CASP2/CASP10/PIK3CD/DFFA/NTRK1/CTSK/CTSH/BCL2L1/DDIT3/ERN1	30
KEGG	hsa05134	Legionellosis	16/988	57/8135	0.0009048	0.03732	0.03357	NFKB2/HSPA1L/BNIP3/NFKBIA/HSPA1A/CR1/CASP9/CASP7/CASP1/SAR1A/IL12A/CLK4/HSF1/PYCARD/HSPA8/HSPD1	16
KEGG	hsa03020	RNA polymerase	11/988	34/8135	0.001617	0.05928	0.05332	CRCP/POLR2C/POLR2J3/POLR2D/CD3EAP/POLR2H/POLR3C/POLR2A/POLR3E/POLR1A/TWISTNB	11
KEGG	hsa04710	Circadian rhythm	10/988	31/8135	0.00268	0.08844	0.07955	PER1/CRY2/PRKAG2/PRKAB1/BTRC/ARNTL/FBXW11/CSNK1E/CSNK1D/RORA	10
KEGG	hsa04910	Insulin signaling pathway	28/988	137/8135	0.003617	0.1085	0.09761	PRKAG2/PPP1R3B/PIK3CA/PPP1R3D/RAF1/PTPN1/TSC1/PRKAB1/EXOC7/SOCS4/HKDC1/TSC2/PRKCI/CALML4/MTOR/SOS1/PIK3CB/PYGM/RPS6KB2/PIK3CD/SOCS2/CBLB/RPTOR/FLOT1/CALM3/LIPE/HK1/PYGL	28
KEGG	hsa04722	Neurotrophin signaling pathway	25/988	119/8135	0.003976	0.1093	0.09835	NFKBIE/ATF4/PIK3CA/CAMK2D/ZNF274/RAF1/NFKBIA/SH2B3/MAP3K3/MAP2K7/NFKBIB/NGFR/PRDM4/RPS6KA5/CALML4/SOS1/PIK3CB/RPS6KA1/MAPKAPK2/PIK3CD/NTRK1/MAP2K5/TRAF6/YWHAE/CALM3	25
KEGG	hsa05164	Influenza A	33/988	171/8135	0.004353	0.1105	0.0994	HLA-DRB1/CDK4/HLA-DQA1/RAE1/PIK3CA/CREBBP/TNFRSF10B/FADD/DDX58/KPNA5/RAF1/DNAJB1/OAS2/NFKBIA/IRF7/HNRNPUL1/NFKBIB/TRAF3/NXT1/CASP9/RSAD2/HLA-DMB/PIK3CB/CASP1/TNFSF10/BAK1/HLA-DMA/PIK3CD/IL12A/PYCARD/PML/CALCOCO2/PRKCB	33
KEGG	hsa04625	C-type lectin receptor signaling pathway	22/988	104/8135	0.006111	0.1362	0.1225	NFATC2/PIK3CA/RELB/NFKB2/MAP3K14/RAF1/NFKBIA/BCL10/PLK3/NFATC3/CALML4/BCL3/EGR2/PIK3CB/CASP1/MAPKAPK2/PIK3CD/IL12A/PYCARD/KSR1/CBLB/CALM3	22
KEGG	hsa04213	Longevity regulating pathway - multiple species	15/988	62/8135	0.006189	0.1362	0.1225	PRKAG2/PIK3CA/AKT1S1/HSPA1L/CLPB/PRKAB1/HSPA1A/HDAC2/MTOR/PIK3CB/RPS6KB2/PIK3CD/HSPA8/RPTOR/ADCY9	15
KEGG	hsa05214	Glioma	17/988	75/8135	0.00743	0.1533	0.1379	CDK4/PIK3CA/CAMK2D/RAF1/TGFA/CDKN1A/PDGFA/CALML4/MTOR/SOS1/PIK3CB/DDB2/BAK1/PIK3CD/CAMK1D/CALM3/PRKCB	17
KEGG	hsa04662	B cell receptor signaling pathway	18/988	82/8135	0.00845	0.164	0.1475	NFKBIE/PTPN6/NFATC2/PIK3CA/CD79B/RAF1/NFKBIA/BCL10/NFKBIB/NFATC3/RAC2/SOS1/PIK3CB/FCGR2B/PIK3CD/LILRB3/CD72/PRKCB	18
KEGG	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	19/988	89/8135	0.009412	0.1726	0.1552	NFKBIE/PTPN6/NFATC2/PIK3CA/RAF1/EML4/NFKBIA/PRKCQ/MAP3K3/NFKBIB/CD247/NFATC3/MTOR/PIK3CB/ZAP70/RPS6KB2/PIK3CD/MAP2K6/TRAF6	19
KEGG	hsa04070	Phosphatidylinositol signaling system	20/988	97/8135	0.01155	0.1886	0.1696	PI4K2A/PIK3CA/PI4KA/IP6K1/MTMR14/DGKZ/MTMR3/PIP5K1A/CALML4/INPP5E/PIK3CB/IP6K2/PIK3CD/IMPAD1/PLCD1/PIP5K1C/PPIP5K1/CALM3/INPP5B/PRKCB	20
KEGG	hsa04010	MAPK signaling pathway	49/988	294/8135	0.01234	0.1886	0.1696	ATF4/DUSP8/MAPK8IP2/RELB/NFKB2/MAPK8IP3/HSPA1L/PPM1B/JUND/MAP3K14/ERBB2/RAF1/DUSP10/HSPA1A/MAP3K3/MAP2K7/TGFA/NGFR/MAPKAPK3/PDGFA/RPS6KA5/DUSP1/EFNA4/MAPK8IP1/NFATC3/SRF/RAC2/MAP3K7/SOS1/MAP3K2/RAPGEF2/ARRB1/RPS6KA1/NF1/MAPKAPK2/DUSP7/NTRK1/MAP2K6/CACNA2D2/MAP2K5/PPM1A/TRAF6/HSPA8/ARRB2/FLT4/PLA2G4C/DDIT3/PRKCB/DUSP6	49
KEGG	hsa04660	T cell receptor signaling pathway	21/988	104/8135	0.01242	0.1886	0.1696	NFKBIE/CDK4/PTPN6/NFATC2/ITK/PIK3CA/MAP3K14/RAF1/NFKBIA/BCL10/PRKCQ/MAP2K7/NFKBIB/CD247/NFATC3/MAP3K7/SOS1/PIK3CB/ZAP70/PIK3CD/CBLB	21
KEGG	hsa03018	RNA degradation	17/988	79/8135	0.01257	0.1886	0.1696	BTG2/DDX6/DCP1A/EDC4/LSM6/BTG3/DCP2/MPHOSPH6/EXOSC7/DIS3/TOB2/EXOSC5/C1D/NUDT16/PATL1/ENO2/HSPD1	17
KEGG	hsa05222	Small cell lung cancer	19/988	92/8135	0.01339	0.1921	0.1728	CDK4/PIK3CA/TRAF4/ZBTB17/NFKBIA/ITGA3/CDKN1A/TRAF3/CASP9/PIK3CB/DDB2/BAK1/RXRB/CDKN1B/CDKN2B/PIK3CD/SKP2/BCL2L1/TRAF6	19
KEGG	hsa03410	Base excision repair	9/988	33/8135	0.01427	0.1963	0.1766	XRCC1/FEN1/POLD2/NEIL2/OGG1/APEX2/POLE/POLL/POLB	9
KEGG	hsa05162	Measles	26/988	139/8135	0.01569	0.2032	0.1828	CD46/CDK4/PIK3CA/HSPA1L/TNFAIP3/FADD/DDX58/OAS2/NFKBIA/HSPA1A/IRF7/NFKBIB/TRAF3/CASP9/MAP3K7/PIK3CB/BAK1/CDKN1B/FCGR2B/PIK3CD/IL12A/BCL2L1/TRAF6/RAB9A/HSPA8/CBLB	26
KEGG	hsa04110	Cell cycle	24/988	126/8135	0.01601	0.2032	0.1828	CDK4/CDKN2D/DBF4/CREBBP/ANAPC7/FZR1/CHEK2/ZBTB17/CDKN1C/CDKN1A/CDK7/HDAC2/MCM7/STAG2/TFDP2/CDKN1B/CDKN2B/CCNH/SKP2/ANAPC2/MCM2/PRKDC/YWHAE/TTK	24
KEGG	hsa05212	Pancreatic cancer	16/988	76/8135	0.01858	0.2192	0.1972	CDK4/PIK3CA/ERBB2/RAF1/TGFA/CDKN1A/CASP9/RAC2/MTOR/RALB/PIK3CB/DDB2/BAK1/RPS6KB2/PIK3CD/BCL2L1	16
KEGG	hsa04120	Ubiquitin mediated proteolysis	26/988	142/8135	0.02029	0.2192	0.1972	UBOX5/ANAPC7/RNF7/FZR1/SMURF1/UBE2B/UBE2L6/HERC2/CUL7/BTRC/DDB1/UBE2S/DDB2/FBXW11/HERC1/SKP2/HERC4/ANAPC2/TRAF6/PML/CBLB/UBE2Q2/UBE2J2/FBXO2/AIRE/NHLRC1	26
KEGG	hsa04066	HIF-1 signaling pathway	21/988	109/8135	0.02062	0.2192	0.1972	EGLN2/PDHA1/PIK3CA/CREBBP/CAMK2D/ERBB2/CDKN1A/SLC2A1/HKDC1/ALDOA/MTOR/PIK3CB/TFRC/EGLN3/CDKN1B/RPS6KB2/PIK3CD/HMOX1/ENO2/HK1/PRKCB	21
KEGG	hsa04150	mTOR signaling pathway	28/988	156/8135	0.0211	0.2192	0.1972	TELO2/SLC3A2/RICTOR/FZD6/ULK1/PIK3CA/AKT1S1/STRADB/RAF1/TSC1/MAPKAP1/ATP6V1G1/TSC2/ATP6V1E1/LAMTOR2/MTOR/SOS1/LAMTOR1/PIK3CB/GRB10/RPS6KA1/RPS6KB2/PIK3CD/CLIP1/SKP2/RPTOR/DEPDC5/PRKCB	28
KEGG	hsa00531	Glycosaminoglycan degradation	6/988	19/8135	0.02122	0.2192	0.1972	HYAL3/SGSH/IDS/HPSE/HYAL2/GALNS	6
KEGG	hsa05017	Spinocerebellar ataxia	26/988	143/8135	0.02204	0.2192	0.1972	NRBF2/ATXN1L/ULK1/PIK3CA/PPIF/ATG14/PSMA5/ATG2B/AMBRA1/GTF2B/PSMD7/ATP2A3/PSMD6/MTOR/PIK3CB/ATG2A/RB1CC1/PIK3CD/TBPL1/BEAN1/PSMC2/RORA/KAT5/AFG3L2/PRKCB/ERN1	26
KEGG	hsa04330	Notch signaling pathway	13/988	59/8135	0.02252	0.2192	0.1972	NCOR2/ATXN1L/CIR1/CREBBP/NCSTN/DTX3L/HDAC2/MAML1/JAG2/LFNG/DTX1/APH1B/RFNG	13
KEGG	hsa03420	Nucleotide excision repair	11/988	47/8135	0.02259	0.2192	0.1972	MNAT1/CDK7/ERCC6/DDB1/DDB2/RPA2/POLD2/RPA1/CCNH/POLE/RFC2	11
KEGG	hsa05135	Yersinia infection	25/988	137/8135	0.02342	0.2208	0.1986	NFATC2/PIK3CA/ITGA5/NFKBIA/MAP2K7/NFATC3/PIP5K1A/RAC2/PKN2/MAP3K7/PIK3CB/CASP1/ARHGEF1/WASL/RPS6KA1/ZAP70/RHOG/ARPC1B/PIK3CD/MAP2K6/ELMO1/PYCARD/PIP5K1C/TRAF6/LIMK1	25
KEGG	hsa05223	Non-small cell lung cancer	15/988	72/8135	0.02429	0.2227	0.2003	CDK4/PIK3CA/ERBB2/RAF1/EML4/TGFA/CDKN1A/CASP9/SOS1/PIK3CB/DDB2/BAK1/RXRB/PIK3CD/PRKCB	15
KEGG	hsa04145	Phagosome	27/988	152/8135	0.02626	0.2342	0.2107	HLA-DRB1/HLA-DQA1/TUBA1A/ITGA5/M6PR/HLA-E/TUBB6/ATP6V1G1/TUBA4A/THBS3/ATP6V1E1/THBS1/DYNC1LI2/HLA-DMB/VAMP3/LAMP1/SEC61A2/TFRC/HLA-DMA/ATP6V0E1/TUBB4B/FCGR2B/RILP/ATP6V0C/FCGR2C/TUBB2A/TAP1	27
KEGG	hsa05210	Colorectal cancer	17/988	86/8135	0.02786	0.242	0.2177	PIK3CA/RAF1/PMAIP1/TGFA/CDKN1A/CASP9/RAC2/MTOR/SOS1/RALB/PIK3CB/DDB2/BAK1/RPS6KB2/PIK3CD/CTNNB1/TCF7L2	17
KEGG	hsa00563	Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	7/988	26/8135	0.03143	0.2659	0.2392	PIGA/PIGL/GPAA1/DPM2/PIGH/MPPE1/PIGO	7
KEGG	hsa04919	Thyroid hormone signaling pathway	22/988	121/8135	0.03326	0.2744	0.2468	PIK3CA/CREBBP/MED13L/RAF1/NCOA2/NCOA3/SLC2A1/MED4/HDAC2/TSC2/ATP1B2/CASP9/ATP2A3/MTOR/PIK3CB/RXRB/PIK3CD/CTNNB1/PLCD1/BMP4/NCOA1/PRKCB	22
KEGG	hsa03013	Nucleocytoplasmic transport	20/988	108/8135	0.03454	0.278	0.2501	TNPO2/RAE1/NUP50/UPF1/DDX19B/KPNA5/TNPO1/NXT1/NUP133/XPO4/NUP43/NUP153/NUP93/SAP18/SENP2/SUMO3/POM121C/TMEM33/UPF2/AAAS	20
KEGG	hsa04211	Longevity regulating pathway	17/988	89/8135	0.03756	0.2951	0.2655	ATF4/PRKAG2/ULK1/PIK3CA/AKT1S1/EHMT2/TSC1/PRKAB1/TSC2/MTOR/PIK3CB/RB1CC1/ADIPOR1/RPS6KB2/PIK3CD/RPTOR/ADCY9	17
KEGG	hsa04068	FoxO signaling pathway	23/988	131/8135	0.04281	0.3244	0.2918	CDKN2D/PRKAG2/PIK3CA/CREBBP/S1PR4/BNIP3/BCL6/FBXO32/RAF1/PRKAB1/CDKN1A/PLK4/PLK3/SOS1/PIK3CB/TNFSF10/GABARAPL1/KLF2/CDKN1B/CDKN2B/PIK3CD/CSNK1E/SKP2	23
KEGG	hsa05213	Endometrial cancer	12/988	58/8135	0.04326	0.3244	0.2918	PIK3CA/ERBB2/RAF1/CDKN1A/CASP9/SOS1/PIK3CB/DDB2/BAK1/PIK3CD/CTNNB1/TCF7L2	12
KEGG	hsa04750	Inflammatory mediator regulation of TRP channels	18/988	98/8135	0.0465	0.3336	0.3001	PTGER4/PIK3CA/CAMK2D/PRKCQ/PRKCE/PRKCH/CALML4/ASIC1/PIK3CB/PIK3CD/TRPV2/NTRK1/MAP2K6/F2RL1/CALM3/ADCY9/PLA2G4C/PRKCB	18
KEGG	hsa05231	Choline metabolism in cancer	18/988	98/8135	0.0465	0.3336	0.3001	PIK3CA/RAF1/TSC1/DGKZ/PDGFA/TSC2/PIP5K1A/RAC2/MTOR/SOS1/PIK3CB/RPS6KB2/PIK3CD/PIP5K1C/SLC22A5/SLC44A2/PLA2G4C/PRKCB	18
KEGG	hsa04012	ErbB signaling pathway	16/988	85/8135	0.04807	0.3338	0.3003	PIK3CA/CAMK2D/ERBB2/RAF1/MAP2K7/TGFA/CDKN1A/HBEGF/MTOR/SOS1/PIK3CB/CDKN1B/RPS6KB2/PIK3CD/CBLB/PRKCB	16
KEGG	hsa04370	VEGF signaling pathway	12/988	59/8135	0.04855	0.3338	0.3003	NFATC2/PIK3CA/RAF1/MAPKAPK3/CASP9/RAC2/PIK3CB/MAPKAPK2/PIK3CD/SPHK2/PLA2G4C/PRKCB	12
KEGG	hsa04115	p53 signaling pathway	14/988	73/8135	0.05406	0.3641	0.3275	CDK4/TNFRSF10B/CHEK2/SIVA1/GORAB/PMAIP1/CDKN1A/TSC2/THBS1/CASP9/SHISA5/DDB2/CCNG1/BCL2L1	14
KEGG	hsa04931	Insulin resistance	19/988	108/8135	0.06044	0.3989	0.3588	PRKAG2/PPP1R3B/PIK3CA/PPP1R3D/PTPN1/PRKAB1/NFKBIA/PRKCQ/SLC2A1/PRKCE/CRTC2/MTOR/PIK3CB/RPS6KA1/PYGM/RPS6KB2/PIK3CD/PRKCB/PYGL	19
KEGG	hsa05417	Lipid and atherosclerosis	34/988	215/8135	0.06275	0.3998	0.3596	ATF4/NFATC2/PIK3CA/HSPA1L/TNFRSF10B/CAMK2D/NFKBIA/HSPA1A/IRF7/MAP2K7/CASP6/TRAF3/CASP9/NFATC3/MAP3K7/CALML4/CASP7/PIK3CB/CASP1/TNFSF10/ARHGEF1/RXRB/PIK3CD/IL12A/MAP2K6/NFE2L2/PYCARD/BCL2L1/TRAF6/HSPA8/CALM3/DDIT3/HSPD1/ERN1	34
KEGG	hsa03450	Non-homologous end-joining	4/988	13/8135	0.06299	0.3998	0.3596	POLM/FEN1/PRKDC/POLL	4
KEGG	hsa05216	Thyroid cancer	8/988	37/8135	0.07224	0.4498	0.4046	CCDC6/CDKN1A/DDB2/BAK1/RXRB/NTRK1/CTNNB1/TCF7L2	8
KEGG	hsa04666	Fc gamma R-mediated phagocytosis	17/988	97/8135	0.07496	0.4498	0.4046	PIK3CA/RAF1/DNM2/BIN1/PRKCE/PIP5K1A/RAC2/PIK3CB/ARPC1B/RPS6KB2/FCGR2B/PIK3CD/PIP5K1C/SPHK2/PLA2G4C/LIMK1/PRKCB	17
KEGG	hsa05215	Prostate cancer	17/988	97/8135	0.07496	0.4498	0.4046	ATF4/PIK3CA/CREBBP/ERBB2/RAF1/NFKBIA/TGFA/CDKN1A/PDGFA/CASP9/MTOR/SOS1/PIK3CB/CDKN1B/PIK3CD/CTNNB1/TCF7L2	17
KEGG	hsa05230	Central carbon metabolism in cancer	13/988	70/8135	0.07648	0.4507	0.4054	PDHA1/PIK3CA/ERBB2/RAF1/PGAM4/SLC2A1/HKDC1/MTOR/PIK3CB/PIK3CD/NTRK1/GLS/HK1	13
KEGG	hsa01522	Endocrine resistance	17/988	98/8135	0.08094	0.4559	0.4101	CDK4/PIK3CA/ERBB2/RAF1/CDKN1A/NCOA3/CYP2D6/HBEGF/MTOR/SOS1/PIK3CB/JAG2/CDKN1B/RPS6KB2/PIK3CD/ADCY9/BIK	17
KEGG	hsa05161	Hepatitis B	26/988	162/8135	0.08216	0.4559	0.4101	ATF4/NFATC2/PIK3CA/CREBBP/FADD/DDX58/RAF1/NFKBIA/IRF7/MAP2K7/CDKN1A/TRAF3/CASP9/DDB1/NFATC3/MAP3K7/EGR2/SOS1/PIK3CB/DDB2/HSPG2/CASP10/PIK3CD/MAP2K6/TRAF6/PRKCB	26
KEGG	hsa04520	Adherens junction	13/988	71/8135	0.08374	0.4559	0.4101	PTPN6/CREBBP/ERBB2/PTPN1/YES1/CTNND1/RAC2/MAP3K7/FARP2/WASL/SNAI1/CTNNB1/TCF7L2	13
KEGG	hsa04072	Phospholipase D signaling pathway	24/988	148/8135	0.08401	0.4559	0.4101	LPAR3/PIK3CA/PIK3R5/LPAR2/RAF1/TSC1/DNM2/DGKZ/PDGFA/AGPAT4/TSC2/PIP5K1A/MTOR/SOS1/RALB/PIK3CB/AGPAT3/PIK3CD/AGPAT1/PIP5K1C/SPHK2/CYTH4/ADCY9/PLA2G4C	24
KEGG	hsa04215	Apoptosis - multiple species	7/988	32/8135	0.08514	0.4559	0.4101	FADD/PMAIP1/NGFR/CASP9/CASP7/BAK1/BCL2L1	7
KEGG	hsa04658	Th1 and Th2 cell differentiation	16/988	92/8135	0.08691	0.4559	0.4101	HLA-DRB1/NFKBIE/HLA-DQA1/NFATC2/NFKBIA/PRKCQ/NFKBIB/CD247/MAML1/NFATC3/HLA-DMB/JAG2/HLA-DMA/RUNX3/ZAP70/IL12A	16
KEGG	hsa04144	Endocytosis	38/988	251/8135	0.08704	0.4559	0.4101	RAB11FIP4/HSPA1L/VPS37B/ARFGEF2/CXCR4/SMAP2/CHMP1B/SMURF1/ACAP1/EPN1/DNM2/VPS37D/HLA-E/BIN1/HSPA1A/VPS28/AP2S1/RAB10/PRKCI/PIP5K1A/PARD6G/RAB11FIP1/TFRC/WASL/EPN2/ARRB1/ARPC1B/STAM/RAB11FIP3/PIP5K1C/TRAF6/HSPA8/PML/VPS37C/CBLB/CYTH4/ARRB2/VPS36	38
KEGG	hsa05166	Human T-cell leukemia virus 1 infection	34/988	222/8135	0.08948	0.4614	0.415	HLA-DRB1/ATF4/CDK4/HLA-DQA1/NFATC2/PIK3CA/RELB/NFKB2/CREBBP/ANAPC7/MAP3K14/CHEK2/NFKBIA/HLA-E/MAP3K3/CDKN1A/SLC2A1/NFATC3/SRF/HLA-DMB/CRTC2/EGR2/PIK3CB/CRTC3/HLA-DMA/CDKN2B/PIK3CD/TBPL1/ZFP36/ANAPC2/BCL2L1/KAT5/POLB/ADCY9	34
KEGG	hsa05167	Kaposi sarcoma-associated herpesvirus infection	30/988	194/8135	0.09604	0.4784	0.4304	MICA/CDK4/NFATC2/PIK3CA/CREBBP/PIK3R5/FADD/ATG14/RAF1/NFKBIA/HLA-E/IRF7/MAP2K7/CDKN1A/TRAF3/CASP9/NFATC3/CALML4/MTOR/PIK3CB/BAK1/MAPKAPK2/MICB/PIK3CD/ZFP36/MAP2K6/CTNNB1/CD200R1/TCF7L2/CALM3	30
KEGG	hsa04930	Type II diabetes mellitus	9/988	46/8135	0.09856	0.4784	0.4304	PIK3CA/SOCS4/HKDC1/PRKCE/MTOR/PIK3CB/PIK3CD/SOCS2/HK1	9
KEGG	hsa00562	Inositol phosphate metabolism	13/988	73/8135	0.0995	0.4784	0.4304	PI4K2A/PLCH2/PIK3CA/PI4KA/MTMR14/MTMR3/PIP5K1A/INPP5E/PIK3CB/PIK3CD/PLCD1/PIP5K1C/INPP5B	13
KEGG	hsa00062	Fatty acid elongation	6/988	27/8135	0.1007	0.4784	0.4304	ACOT2/ACOT4/MECR/ECHS1/TECR/ACOT1	6
KEGG	hsa01040	Biosynthesis of unsaturated fatty acids	6/988	27/8135	0.1007	0.4784	0.4304	ACOT2/FADS1/ACOT4/ACAA1/TECR/ACOT1	6
KEGG	hsa05131	Shigellosis	37/988	247/8135	0.1015	0.4784	0.4304	MYL5/PIK3CA/AKT1S1/BNIP3/ATG14/ITGA5/NFKBIA/BCL10/PRKCQ/GSK3A/NFKBIB/HKDC1/PRKCE/BTRC/SHARPIN/RPS6KA5/MAP3K7/MTOR/SQSTM1/PIK3CB/CASP1/FBXW11/WASL/ARPC1B/RPS6KB2/PIK3CD/ELMO1/PLCD1/PYCARD/TECPR1/BCL2L1/TRAF6/CYTH4/RPTOR/MYL12A/HK1/CALCOCO2	37
KEGG	hsa00260	Glycine, serine and threonine metabolism	8/988	40/8135	0.1045	0.4858	0.437	AMT/PGAM4/GNMT/GLYCTK/GRHPR/PSPH/MAOA/SDSL	8
KEGG	hsa05221	Acute myeloid leukemia	12/988	67/8135	0.1069	0.4902	0.4409	PIM1/PIK3CA/RAF1/PIM2/MTOR/SOS1/PIK3CB/RPS6KB2/PIK3CD/PML/TCF7L2/DUSP6	12
KEGG	hsa05203	Viral carcinogenesis	31/988	204/8135	0.1092	0.4936	0.444	ATF4/CDK4/PIK3CA/NFKB2/CREBBP/NFKBIA/HLA-E/PMAIP1/GTF2A1/IRF7/HDAC4/CDKN1A/TRAF3/HDAC2/REL/GTF2B/DDB1/SRF/EGR2/PIK3CB/BAK1/MAPKAPK2/CHD4/CDKN1B/CDKN2B/PIK3CD/TBPL1/SKP2/YWHAE/POLB/HDAC7	31
KEGG	hsa00920	Sulfur metabolism	3/988	10/8135	0.1117	0.4979	0.4479	BPNT1/IMPAD1/ETHE1	3
KEGG	hsa00561	Glycerolipid metabolism	11/988	61/8135	0.115	0.5021	0.4516	DGKZ/PNPLA2/AGPAT4/GLYCTK/GK/PNPLA3/AGPAT3/LIPC/AGPAT1/AGK/GPAT2	11
KEGG	hsa04216	Ferroptosis	8/988	41/8135	0.1168	0.5021	0.4516	SLC3A2/SLC39A14/PRNP/FTL/TFRC/SLC11A2/SLC40A1/HMOX1	8
KEGG	hsa04142	Lysosome	21/988	132/8135	0.1172	0.5021	0.4516	HYAL3/CTSA/M6PR/SUMF1/SGSH/CTSW/GM2A/CTSF/LITAF/LAMP1/IDS/CTSK/CTSH/SCARB2/ARSG/SLC11A2/ATP6V0C/HYAL2/CLN5/ACP2/GALNS	21
KEGG	hsa05220	Chronic myeloid leukemia	13/988	76/8135	0.1263	0.5343	0.4806	CDK4/PIK3CA/RAF1/NFKBIA/CDKN1A/HDAC2/SOS1/PIK3CB/DDB2/BAK1/CDKN1B/PIK3CD/BCL2L1	13
KEGG	hsa05145	Toxoplasmosis	18/988	112/8135	0.1296	0.5415	0.4871	HLA-DRB1/HLA-DQA1/PPIF/HSPA1L/PIK3R5/NFKBIA/HSPA1A/NFKBIB/CASP9/MAP3K7/HLA-DMB/ALOX5/HLA-DMA/IL12A/MAP2K6/BCL2L1/TRAF6/HSPA8	18
KEGG	hsa04141	Protein processing in endoplasmic reticulum	26/988	171/8135	0.1326	0.5468	0.4919	ATF4/UBXN6/PPP1R15A/HSPA1L/DNAJB1/MAN1A2/HSPA1A/MAP2K7/DERL2/YOD1/NPLOC4/SEC31B/DNAJA1/GANAB/BAK1/SAR1A/SEC61A2/NFE2L2/HERPUD1/HSPA8/CKAP4/DNAJC5/DDIT3/UBE2J2/FBXO2/ERN1	26
KEGG	hsa04152	AMPK signaling pathway	19/988	120/8135	0.1356	0.5475	0.4925	PRKAG2/ULK1/PIK3CA/AKT1S1/STRADB/TSC1/PRKAB1/RAB10/TSC2/MAP3K7/CRTC2/MTOR/CPT1C/PIK3CB/ADIPOR1/RPS6KB2/PIK3CD/RPTOR/LIPE	19
KEGG	hsa05140	Leishmaniasis	13/988	77/8135	0.136	0.5475	0.4925	HLA-DRB1/HLA-DQA1/PTPN6/NFKBIA/CR1/NFKBIB/MAP3K7/HLA-DMB/HLA-DMA/IL12A/TRAF6/FCGR2C/PRKCB	13
KEGG	hsa00760	Nicotinate and nicotinamide metabolism	7/988	36/8135	0.1391	0.5531	0.4975	NT5E/NT5C2/BST1/ASPDH/NT5M/NT5C1A/NMRK1	7
KEGG	hsa04380	Osteoclast differentiation	20/988	128/8135	0.1411	0.5544	0.4987	NFATC2/PIK3CA/RELB/NFKB2/JUND/MAP3K14/NFKBIA/FOSB/MAP2K7/SIRPG/MAP3K7/SQSTM1/PIK3CB/FCGR2B/PIK3CD/CTSK/MAP2K6/LILRB3/TRAF6/FCGR2C	20
KEGG	hsa04940	Type I diabetes mellitus	8/988	43/8135	0.1436	0.5561	0.5002	HLA-DRB1/HLA-DQA1/HLA-E/HLA-DMB/HLA-DMA/IL12A/PTPRN2/HSPD1	8
KEGG	hsa01232	Nucleotide metabolism	14/988	85/8135	0.1449	0.5561	0.5002	AMPD2/NT5E/CANT1/NT5C2/NT5M/ENTPD5/GUK1/ASMTL/ENTPD1/NME6/GMPR2/AK1/NUDT16/NT5C1A	14
KEGG	hsa00030	Pentose phosphate pathway	6/988	30/8135	0.1487	0.5623	0.5058	H6PD/RPE/GLYCTK/ALDOA/IDNK/TALDO1	6
KEGG	hsa04912	GnRH signaling pathway	15/988	93/8135	0.1529	0.5623	0.5058	ATF4/CAMK2D/RAF1/MAP3K3/MAP2K7/GNRH1/HBEGF/CALML4/SOS1/MAP3K2/MAP2K6/CALM3/ADCY9/PLA2G4C/PRKCB	15
KEGG	hsa01200	Carbon metabolism	18/988	115/8135	0.1547	0.5623	0.5058	H6PD/PDHA1/AMT/PGAM4/SUCLG2/DLST/RPE/HKDC1/GLYCTK/ALDOA/PSPH/SUCLG1/IDNK/ECHS1/ENO2/TALDO1/HK1/SDSL	18
KEGG	hsa05170	Human immunodeficiency virus 1 infection	31/988	212/8135	0.1556	0.5623	0.5058	NFATC2/PIK3CA/FADD/RNF7/CXCR4/RAF1/NFKBIA/HLA-E/MAP2K7/BTRC/CD247/CASP9/DDB1/NFATC3/RAC2/MAP3K7/CALML4/MTOR/PIK3CB/BAK1/FBXW11/RPS6KB2/PIK3CD/TRIM5/MAP2K6/BCL2L1/TRAF6/CALM3/LIMK1/PRKCB/TAP1	31
KEGG	hsa05130	Pathogenic Escherichia coli infection	29/988	197/8135	0.1561	0.5623	0.5058	ABI1/PTPN6/TUBA1A/TNFRSF10B/FADD/LPAR2/NFKBIA/CLDN15/TUBB6/NFKBIB/TUBA4A/CASP9/EZR/MAP3K7/CASP7/CASP1/TNFSF10/BAK1/ARHGEF1/WASL/TUBB4B/ARPC1B/MYO1H/PYCARD/TRAF6/MYO1C/CYTH4/TUBB2A/MYO5C	29
KEGG	hsa01521	EGFR tyrosine kinase inhibitor resistance	13/988	79/8135	0.1568	0.5623	0.5058	PIK3CA/ERBB2/RAF1/TGFA/PDGFA/MTOR/SOS1/PIK3CB/NF1/RPS6KB2/PIK3CD/BCL2L1/PRKCB	13
KEGG	hsa04915	Estrogen signaling pathway	21/988	138/8135	0.1622	0.5741	0.5164	ATF4/PIK3CA/HSPA1L/RAF1/HSPA1A/TGFA/NCOA2/NCOA3/FKBP4/HBEGF/CALML4/SOS1/PIK3CB/KRT17/PIK3CD/FKBP5/KRT20/HSPA8/NCOA1/CALM3/ADCY9	21
KEGG	hsa05225	Hepatocellular carcinoma	25/988	168/8135	0.1635	0.5741	0.5164	CDK4/SMARCB1/FZD6/PIK3CA/RAF1/ARID1B/TGFA/CDKN1A/MTOR/SOS1/PIK3CB/DDB2/BAK1/RPS6KB2/FRAT1/PIK3CD/ARID2/CTNNB1/NFE2L2/BCL2L1/ARID1A/TCF7L2/GSTM4/HMOX1/PRKCB	25
KEGG	hsa05016	Huntington disease	43/988	306/8135	0.1699	0.5862	0.5273	NRBF2/TUBA1A/ULK1/NRF1/PPIF/CREBBP/DCTN4/DNAH1/ATG14/NDUFA11/POLR2C/POLR2J3/POLR2D/NDUFS1/PSMA5/MAP2K7/TUBB6/NDUFA7/ATG2B/AP2S1/TUBA4A/HDAC2/POLR2H/AMBRA1/CASP9/PSMD7/PSMD6/MTOR/ATG2A/RB1CC1/TUBB4B/TBPL1/POLR2A/COX5B/PSMC2/DCTN6/TUBB2A/IFT57/KLC1/DCTN5/NDUFS7/COX8A/ERN1	43
KEGG	hsa05418	Fluid shear stress and atherosclerosis	21/988	139/8135	0.1705	0.5862	0.5273	PIK3CA/MAP2K7/PDGFA/DUSP1/RAC2/SUMO3/MAP3K7/CALML4/SQSTM1/PIK3CB/ASS1/KLF2/PIK3CD/MAP2K6/CTNNB1/NFE2L2/MAP2K5/BMP4/GSTM4/CALM3/HMOX1	21
KEGG	hsa03022	Basal transcription factors	8/988	45/8135	0.1731	0.5887	0.5296	GTF2I/MNAT1/GTF2A1/TAF15/CDK7/GTF2B/CCNH/TBPL1	8
KEGG	hsa05165	Human papillomavirus infection	46/988	331/8135	0.1803	0.6071	0.5461	CDK4/PTGER4/FZD6/PIK3CA/CREBBP/FADD/ISG15/ITGA5/RAF1/TSC1/NFX1/HLA-E/ITGA10/ITGA3/CDKN1A/ATP6V1G1/TRAF3/HDAC2/THBS3/TSC2/ATP6V1E1/THBS1/PRKCI/MAML1/PARD6G/VTN/MTOR/SOS1/PIK3CB/COL1A1/BAK1/LFNG/TUBG2/HES7/ATP6V0E1/COL6A2/CHD4/CDKN1B/RPS6KB2/PIK3CD/TBPL1/CTNNB1/ATP6V0C/TCF7L2/LLGL2/RFNG	46
KEGG	hsa04136	Autophagy - other	6/988	32/8135	0.1855	0.6184	0.5563	ATG2B/ATG4D/MTOR/GABARAPL1/ATG2A/RPTOR	6
KEGG	hsa04015	Rap1 signaling pathway	30/988	210/8135	0.1942	0.6409	0.5765	LPAR3/PIK3CA/LPAR2/RAF1/ID1/RAP1GAP/NGFR/PDGFA/EFNA4/THBS1/PRKCI/CTNND1/RAC2/PARD6G/EVL/CALML4/RALB/PIK3CB/FARP2/RAPGEF2/PIK3CD/MAP2K6/CTNNB1/RGS14/FLT4/CALM3/ADCY9/SIPA1L1/PRKCB/FPR1	30
KEGG	hsa04668	TNF signaling pathway	17/988	112/8135	0.1962	0.6412	0.5768	ATF4/CFLAR/PIK3CA/TNFAIP3/FADD/MAP3K14/NFKBIA/MAP2K7/TRAF3/RPS6KA5/MAP3K7/BCL3/CASP7/PIK3CB/CASP10/PIK3CD/MAP2K6	17
KEGG	hsa04130	SNARE interactions in vesicular transport	6/988	33/8135	0.2051	0.6636	0.597	BNIP1/STX5/STX8/VAMP3/BET1L/GOSR1	6
KEGG	hsa04920	Adipocytokine signaling pathway	11/988	69/8135	0.2109	0.6693	0.6021	NFKBIE/PRKAG2/PRKAB1/NFKBIA/PRKCQ/SLC2A1/NFKBIB/MTOR/CPT1C/RXRB/ADIPOR1	11
KEGG	hsa05211	Renal cell carcinoma	11/988	69/8135	0.2109	0.6693	0.6021	EGLN2/PIK3CA/CREBBP/RAF1/TGFA/CDKN1A/SLC2A1/SOS1/PIK3CB/EGLN3/PIK3CD	11
KEGG	hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	4/988	20/8135	0.2188	0.687	0.618	B4GALT7/CHST14/CSGALNACT2/XYLT1	4
KEGG	hsa05219	Bladder cancer	7/988	41/8135	0.2242	0.687	0.618	CDK4/ERBB2/RAF1/CDKN1A/RPS6KA5/THBS1/HBEGF	7
KEGG	hsa04966	Collecting duct acid secretion	5/988	27/8135	0.2243	0.687	0.618	ATP6V1G1/ATP6V1E1/ATP6V0E1/SLC12A7/ATP6V0C	5
KEGG	hsa04622	RIG-I-like receptor signaling pathway	11/988	70/8135	0.2248	0.687	0.618	FADD/ISG15/DDX58/NFKBIA/IRF7/NFKBIB/TRAF3/MAP3K7/CASP10/IL12A/TRAF6	11
KEGG	hsa04659	Th17 cell differentiation	16/988	108/8135	0.2342	0.7035	0.6328	HLA-DRB1/NFKBIE/HLA-DQA1/NFATC2/NFKBIA/PRKCQ/NFKBIB/CD247/NFATC3/HLA-DMB/MTOR/HLA-DMA/RXRB/IL17A/ZAP70/RORA	16
KEGG	hsa04340	Hedgehog signaling pathway	9/988	56/8135	0.2345	0.7035	0.6328	SMURF1/BTRC/FBXW11/ARRB1/MEGF8/CSNK1G2/CSNK1E/CSNK1D/ARRB2	9
KEGG	hsa04650	Natural killer cell mediated cytotoxicity	19/988	131/8135	0.2372	0.7051	0.6343	MICA/PTPN6/NFATC2/PIK3CA/TNFRSF10B/RAF1/HLA-E/CD247/RAC2/SOS1/PIK3CB/TNFSF10/ZAP70/MICB/PIK3CD/SH2D1A/NCR3/ICAM2/PRKCB	19
KEGG	hsa05224	Breast cancer	21/988	147/8135	0.2447	0.7209	0.6485	CDK4/FZD6/PIK3CA/NFKB2/ERBB2/RAF1/CDKN1A/NCOA3/MTOR/SOS1/PIK3CB/DDB2/BAK1/JAG2/RPS6KB2/FRAT1/PIK3CD/CTNNB1/TCF7L2/NCOA1/FLT4	21
KEGG	hsa05152	Tuberculosis	25/988	180/8135	0.2655	0.7574	0.6813	HLA-DRB1/HLA-DQA1/CREBBP/FADD/CAMK2D/RAF1/BCL10/CR1/CASP9/PLK3/CALML4/HLA-DMB/LAMP1/HLA-DMA/CASP10/FCGR2B/CEBPG/IL12A/SPHK2/TRAF6/KSR1/ATP6V0C/FCGR2C/CALM3/HSPD1	25
KEGG	hsa04540	Gap junction	13/988	88/8135	0.2674	0.7574	0.6813	TUBA1A/RAF1/TUBB6/PDGFA/TUBA4A/SOS1/MAP3K2/TUBB4B/MAP2K5/CSNK1D/TUBB2A/ADCY9/PRKCB	13
KEGG	hsa00240	Pyrimidine metabolism	9/988	58/8135	0.2676	0.7574	0.6813	NT5E/CANT1/NT5C2/NT5M/ENTPD5/ASMTL/ENTPD1/NME6/NT5C1A	9
KEGG	hsa05160	Hepatitis C	22/988	157/8135	0.2679	0.7574	0.6813	CDK4/CFLAR/IFIT1/PIK3CA/FADD/DDX58/RAF1/OAS2/NFKBIA/IRF7/CLDN15/CDKN1A/TRAF3/CASP9/RSAD2/SOS1/PIK3CB/BAK1/PIK3CD/CTNNB1/TRAF6/YWHAE	22
KEGG	hsa01524	Platinum drug resistance	11/988	73/8135	0.2685	0.7574	0.6813	PIK3CA/FADD/ERBB2/PMAIP1/CDKN1A/CASP9/PIK3CB/BAK1/PIK3CD/BCL2L1/GSTM4	11
KEGG	hsa00604	Glycosphingolipid biosynthesis - ganglio series	3/988	15/8135	0.2715	0.7593	0.683	ST3GAL5/B3GALT4/ST6GALNAC6	3
KEGG	hsa04064	NF-kappa B signaling pathway	15/988	104/8135	0.2776	0.7699	0.6926	CFLAR/RELB/NFKB2/TNFAIP3/DDX58/MAP3K14/NFKBIA/BCL10/PRKCQ/TRAF3/MAP3K7/ZAP70/BCL2L1/TRAF6/PRKCB	15
KEGG	hsa00230	Purine metabolism	18/988	128/8135	0.2889	0.7841	0.7053	AMPD2/GART/NUDT9/NT5E/CANT1/PDE6H/NT5C2/NT5M/ENTPD5/GUK1/ENTPD1/NME6/GMPR2/AK1/NUDT16/PDE2A/NT5C1A/ADCY9	18
KEGG	hsa01250	Biosynthesis of nucleotide sugars	6/988	37/8135	0.2897	0.7841	0.7053	HKDC1/GNE/UGDH/GMPPB/UAP1/HK1	6
KEGG	hsa05014	Amyotrophic lateral sclerosis	48/988	364/8135	0.2899	0.7841	0.7053	SMCR8/NRBF2/ATF4/RAE1/NUP50/HNRNPA1L2/TUBA1A/ULK1/DCTN4/DNAH1/ATG14/NDUFA11/NDUFS1/PSMA5/TUBB6/NDUFA7/ATG2B/TUBA4A/NXT1/NUP133/NUP43/NUP153/AMBRA1/NUP93/CASP9/PSMD7/PSMD6/POM121C/MTOR/SQSTM1/CASP1/ATG2A/RB1CC1/TUBB4B/SRSF3/TOMM40L/MAP2K6/COX5B/BCL2L1/PSMC2/DCTN6/TUBB2A/KLC1/DCTN5/DDIT3/NDUFS7/COX8A/ERN1	48
KEGG	hsa00515	Mannose type O-glycan biosynthesis	4/988	23/8135	0.3031	0.7918	0.7122	FKRP/CHST10/POMT2/FKTN	4
KEGG	hsa03430	Mismatch repair	4/988	23/8135	0.3031	0.7918	0.7122	RPA2/POLD2/RPA1/RFC2	4
KEGG	hsa04964	Proximal tubule bicarbonate reclamation	4/988	23/8135	0.3031	0.7918	0.7122	ATP1B2/CA4/AQP1/GLS	4
KEGG	hsa04928	Parathyroid hormone synthesis, secretion and action	15/988	106/8135	0.3034	0.7918	0.7122	ATF4/MEF2D/JUND/RAF1/NR4A2/CDKN1A/MMP17/HBEGF/CASR/ARHGEF1/ARRB1/RXRB/ARRB2/ADCY9/PRKCB	15
KEGG	hsa00430	Taurine and hypotaurine metabolism	3/988	16/8135	0.3065	0.7918	0.7122	ADO/GGT1/FMO4	3
KEGG	hsa04664	Fc epsilon RI signaling pathway	10/988	68/8135	0.3089	0.7918	0.7122	PIK3CA/RAF1/MAP2K7/RAC2/SOS1/PIK3CB/ALOX5/PIK3CD/MAP2K6/PLA2G4C	10
KEGG	hsa04714	Thermogenesis	31/988	232/8135	0.3112	0.7918	0.7122	SMARCB1/PRKAG2/COX19/AKT1S1/NDUFA11/TSC1/CPT2/PRKAB1/NDUFS1/ARID1B/NDUFA7/PNPLA2/NDUFAF5/COA5/TSC2/NDUFAF1/MTOR/SOS1/CPT1C/RPS6KA1/RPS6KB2/KDM3B/BMP8B/NDUFAF6/COX5B/ARID1A/RPTOR/ADCY9/LIPE/NDUFS7/COX8A	31
KEGG	hsa05330	Allograft rejection	6/988	38/8135	0.3119	0.7918	0.7122	HLA-DRB1/HLA-DQA1/HLA-E/HLA-DMB/HLA-DMA/IL12A	6
KEGG	hsa04922	Glucagon signaling pathway	15/988	107/8135	0.3166	0.7925	0.7128	ATF4/PRKAG2/PDHA1/CREBBP/CAMK2D/PGAM4/PRKAB1/SLC2A1/SIK1/CALML4/CRTC2/CPT1C/PYGM/CALM3/PYGL	15
KEGG	hsa05010	Alzheimer disease	50/988	384/8135	0.3183	0.7925	0.7128	NRBF2/ATF4/TUBA1A/FZD6/ULK1/PIK3CA/PPIF/FADD/NCSTN/SLC39A14/ATG14/RAF1/NDUFA11/NDUFS1/PSMA5/MAP2K7/TUBB6/NDUFA7/ATG2B/TUBA4A/AMBRA1/CASP9/PSMD7/ATP2A3/PSMD6/CALML4/MTOR/CASP7/PIK3CB/ATG2A/RB1CC1/APBB1/TUBB4B/FRAT1/PIK3CD/CSNK1E/CTNNB1/SLC11A2/COX5B/PSMC2/TUBB2A/CDK5/KLC1/CALM3/APH1B/DDIT3/CHRM3/NDUFS7/COX8A/ERN1	50
KEGG	hsa05163	Human cytomegalovirus infection	30/988	225/8135	0.3194	0.7925	0.7128	ATF4/CDK4/PTGER4/NFATC2/PIK3CA/FADD/CXCR4/RAF1/TSC1/NFKBIA/HLA-E/CDKN1A/TSC2/CASP9/NFATC3/RAC2/CALML4/MTOR/SOS1/PIK3CB/BAK1/ARHGEF1/RPS6KB2/PIK3CD/MAP2K6/CTNNB1/CALM3/ADCY9/PRKCB/TAP1	30
KEGG	hsa05100	Bacterial invasion of epithelial cells	11/988	77/8135	0.3305	0.8056	0.7247	PIK3CA/ITGA5/DNM2/PIK3CB/WASL/RHOG/ARPC1B/PIK3CD/ELMO1/CTNNB1/ARHGEF26	11
KEGG	hsa03460	Fanconi anemia pathway	8/988	54/8135	0.3309	0.8056	0.7247	TELO2/FANCE/ATRIP/WDR48/TOP3B/RPA2/RPA1/RMI2	8
KEGG	hsa00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	4/988	24/8135	0.332	0.8056	0.7247	B4GALT7/NDST2/EXT1/XYLT1	4
KEGG	hsa04218	Cellular senescence	21/988	156/8135	0.3409	0.8152	0.7333	CDK4/NFATC2/PIK3CA/RAF1/CHEK2/TSC1/HLA-E/CDKN1A/BTRC/TSC2/NFATC3/CALML4/MTOR/SQSTM1/PIK3CB/FBXW11/MAPKAPK2/CDKN2B/PIK3CD/MAP2K6/CALM3	21
KEGG	hsa00514	Other types of O-glycan biosynthesis	7/988	47/8135	0.3434	0.8152	0.7333	ST6GAL1/GALNT3/GALNT10/LFNG/C1GALT1C1/POMT2/RFNG	7
KEGG	hsa04973	Carbohydrate digestion and absorption	7/988	47/8135	0.3434	0.8152	0.7333	PIK3CA/HKDC1/ATP1B2/PIK3CB/PIK3CD/HK1/PRKCB	7
KEGG	hsa04657	IL-17 signaling pathway	13/988	94/8135	0.3526	0.831	0.7475	TNFAIP3/FADD/TRAF4/JUND/NFKBIA/FOSB/IL17C/TRAF3/SRSF1/MAP3K7/IL17A/TRAF6/MAPK6	13
KEGG	hsa04623	Cytosolic DNA-sensing pathway	9/988	63/8135	0.3552	0.8314	0.7478	DDX58/NFKBIA/IRF7/NFKBIB/POLR2H/POLR3C/CASP1/POLR3E/PYCARD	9
KEGG	hsa04929	GnRH secretion	9/988	64/8135	0.3733	0.8674	0.7803	PIK3CA/RAF1/GNRH1/HCN2/PIK3CB/ARRB1/PIK3CD/ARRB2/PRKCB	9
KEGG	hsa03440	Homologous recombination	6/988	41/8135	0.3799	0.8767	0.7886	TOP3B/RAD54B/RPA2/POLD2/RPA1/RAD52	6
KEGG	hsa00520	Amino sugar and nucleotide sugar metabolism	7/988	49/8135	0.385	0.8794	0.791	HKDC1/GNE/UGDH/GMPPB/AMDHD2/UAP1/HK1	7
KEGG	hsa04621	NOD-like receptor signaling pathway	24/988	184/8135	0.3864	0.8794	0.791	GBP1/P2RX7/TNFAIP3/FADD/OAS2/NFKBIA/GBP4/IRF7/NFKBIB/TRAF3/SHARPIN/NEK7/PKN2/MAP3K7/CASP1/CASR/GABARAPL1/GSDMD/TRPV2/CARD6/PYCARD/BCL2L1/TRAF6/YWHAE	24
KEGG	hsa00130	Ubiquinone and other terpenoid-quinone biosynthesis	2/988	11/8135	0.3934	0.8892	0.7999	VKORC1/VKORC1L1	2
KEGG	hsa04670	Leukocyte transendothelial migration	15/988	114/8135	0.4117	0.9242	0.8314	MYL5/ITK/PIK3CA/CXCR4/F11R/CLDN15/EZR/CTNND1/RAC2/PIK3CB/RHOH/PIK3CD/CTNNB1/MYL12A/PRKCB	15
KEGG	hsa04913	Ovarian steroidogenesis	7/988	51/8135	0.4267	0.9472	0.8521	ACOT2/ALOX5/ACOT4/ADCY9/PLA2G4C/CYP17A1/ACOT1	7
KEGG	hsa01230	Biosynthesis of amino acids	10/988	75/8135	0.4277	0.9472	0.8521	PGAM4/MAT2A/RPE/ALDOA/ASS1/NAGS/PSPH/ENO2/TALDO1/SDSL	10
KEGG	hsa00670	One carbon pool by folate	3/988	20/8135	0.4451	0.9603	0.8638	GART/AMT/MTHFS	3
KEGG	hsa05416	Viral myocarditis	8/988	60/8135	0.4467	0.9603	0.8638	HLA-DRB1/HLA-DQA1/HLA-E/CASP9/RAC2/HLA-DMB/HLA-DMA/CD55	8
KEGG	hsa00650	Butanoate metabolism	4/988	28/8135	0.4475	0.9603	0.8638	OXCT2/BDH1/ECHS1/ABAT	4
KEGG	hsa04962	Vasopressin-regulated water reabsorption	6/988	44/8135	0.448	0.9603	0.8638	DCTN4/DYNC1LI2/DYNLL1/DCTN6/ADCY9/DCTN5	6
KEGG	hsa00500	Starch and sucrose metabolism	5/988	36/8135	0.4481	0.9603	0.8638	GBE1/HKDC1/PYGM/HK1/PYGL	5
KEGG	hsa05022	Pathways of neurodegeneration - multiple diseases	59/988	476/8135	0.454	0.9665	0.8694	SMCR8/NRBF2/ATF4/ATXN1L/TUBA1A/FZD6/ULK1/PPIF/DCTN4/FADD/CAMK2D/DNAH1/ATG14/RAF1/NDUFA11/UBE2L6/PRNP/NDUFS1/PSMA5/MAP2K7/TUBB6/NDUFA7/ATG2B/TUBA4A/AMBRA1/CASP9/PSMD7/ATP2A3/PSMD6/CALML4/MTOR/CASP7/SQSTM1/BAK1/ATG2A/RB1CC1/TUBB4B/FRAT1/TOMM40L/MAP2K6/CSNK1E/CTNNB1/COX5B/BCL2L1/PSMC2/DCTN6/TUBB2A/CDK5/IFT57/KLC1/CALM3/DCTN5/DDIT3/CHRM3/NDUFS7/UBE2J2/PRKCB/COX8A/ERN1	59
KEGG	hsa04960	Aldosterone-regulated sodium reabsorption	5/988	37/8135	0.4729	0.9937	0.8938	PIK3CA/ATP1B2/PIK3CB/PIK3CD/PRKCB	5
KEGG	hsa05143	African trypanosomiasis	5/988	37/8135	0.4729	0.9937	0.8938	APOL1/IL12A/HBB/F2RL1/PRKCB	5
KEGG	hsa05012	Parkinson disease	33/988	266/8135	0.4762	0.9937	0.8938	ATF4/TUBA1A/PPIF/SLC39A14/CAMK2D/NDUFA11/UBE2L6/NDUFS1/PSMA5/TUBB6/NDUFA7/TUBA4A/DUSP1/CASP9/PSMD7/PSMD6/CALML4/GNAL/TUBB4B/NFE2L2/SLC11A2/COX5B/BCL2L1/PSMC2/TUBB2A/KLC1/CALM3/MAOA/DDIT3/NDUFS7/UBE2J2/COX8A/ERN1	33
KEGG	hsa04612	Antigen processing and presentation	10/988	78/8135	0.4789	0.9937	0.8938	HLA-DRB1/HLA-DQA1/HSPA1L/HLA-E/HSPA1A/IFI30/HLA-DMB/HLA-DMA/HSPA8/TAP1	10
KEGG	hsa04917	Prolactin signaling pathway	9/988	70/8135	0.4818	0.9937	0.8938	CISH/PIK3CA/RAF1/SOCS4/SOS1/PIK3CB/PIK3CD/SOCS2/CYP17A1	9
KEGG	hsa04620	Toll-like receptor signaling pathway	13/988	104/8135	0.5008	1	0.8995	PIK3CA/FADD/NFKBIA/IRF7/MAP2K7/TRAF3/MAP3K7/PIK3CB/PIK3CD/IL12A/CTSK/MAP2K6/TRAF6	13
KEGG	hsa00020	Citrate cycle (TCA cycle)	4/988	30/8135	0.503	1	0.8995	PDHA1/SUCLG2/DLST/SUCLG1	4
KEGG	hsa03250	Viral life cycle - HIV-1	8/988	63/8135	0.5038	1	0.8995	SMARCB1/CCNT1/CREBBP/CXCR4/NUP153/SUPT5H/TRIM5/FURIN	8
KEGG	hsa00220	Arginine biosynthesis	3/988	22/8135	0.5104	1	0.8995	ASS1/NAGS/GLS	3
KEGG	hsa04137	Mitophagy - animal	9/988	72/8135	0.5172	1	0.8995	ATF4/ULK1/BNIP3/AMBRA1/SQSTM1/GABARAPL1/BCL2L1/TBC1D15/CALCOCO2	9
KEGG	hsa05218	Melanoma	9/988	72/8135	0.5172	1	0.8995	CDK4/PIK3CA/RAF1/CDKN1A/PDGFA/PIK3CB/DDB2/BAK1/PIK3CD	9
KEGG	hsa04923	Regulation of lipolysis in adipocytes	7/988	56/8135	0.5286	1	0.8995	PIK3CA/PNPLA2/PIK3CB/PIK3CD/PTGS1/ADCY9/LIPE	7
KEGG	hsa05310	Asthma	4/988	31/8135	0.5298	1	0.8995	HLA-DRB1/HLA-DQA1/HLA-DMB/HLA-DMA	4
KEGG	hsa04925	Aldosterone synthesis and secretion	12/988	98/8135	0.5345	1	0.8995	ATF4/CAMK2D/NR4A2/PRKCE/ATP1B2/CALML4/PDE2A/CAMK1D/CALM3/ADCY9/LIPE/PRKCB	12
KEGG	hsa05226	Gastric cancer	18/988	149/8135	0.5479	1	0.8995	FZD6/PIK3CA/ERBB2/RAF1/CDKN1A/MTOR/SOS1/PIK3CB/DDB2/BAK1/RXRB/CDKN1B/CDKN2B/RPS6KB2/FRAT1/PIK3CD/CTNNB1/TCF7L2	18
KEGG	hsa01212	Fatty acid metabolism	7/988	57/8135	0.5482	1	0.8995	CPT2/CPT1C/FADS1/ACAA1/MECR/ECHS1/TECR	7
KEGG	hsa00640	Propanoate metabolism	4/988	32/8135	0.5559	1	0.8995	SUCLG2/SUCLG1/ECHS1/ABAT	4
KEGG	hsa04672	Intestinal immune network for IgA production	6/988	49/8135	0.5569	1	0.8995	HLA-DRB1/HLA-DQA1/CXCR4/MAP3K14/HLA-DMB/HLA-DMA	6
KEGG	hsa04936	Alcoholic liver disease	17/988	142/8135	0.5645	1	0.8995	PRKAG2/FADD/MAP3K14/PRKAB1/NFKBIA/MAP2K7/TRAF3/MAP3K7/CPT1C/C5/IL17A/ADIPOR1/IL12A/MAP2K6/CTNNB1/TRAF6/TCF7L2	17
KEGG	hsa03008	Ribosome biogenesis in eukaryotes	13/988	109/8135	0.5724	1	0.8995	NOL6/GNL3/RPP38/REXO1/NOP10/WDR43/RPP40/NXT1/POP1/IMP4/UTP14C/POP7/RIOK1	13
KEGG	hsa04720	Long-term potentiation	8/988	67/8135	0.5768	1	0.8995	ATF4/CREBBP/CAMK2D/RAF1/CALML4/RPS6KA1/CALM3/PRKCB	8
KEGG	hsa00510	N-Glycan biosynthesis	6/988	50/8135	0.5775	1	0.8995	ST6GAL1/MAN1A2/MAN2A2/GANAB/ALG2/DPM2	6
KEGG	hsa05110	Vibrio cholerae infection	6/988	50/8135	0.5775	1	0.8995	ATP6V1G1/ATP6V1E1/SEC61A2/ATP6V0E1/ATP6V0C/ADCY9	6
KEGG	hsa00051	Fructose and mannose metabolism	4/988	33/8135	0.5812	1	0.8995	HKDC1/ALDOA/GMPPB/HK1	4
KEGG	hsa04971	Gastric acid secretion	9/988	76/8135	0.5853	1	0.8995	CAMK2D/ATP1B2/EZR/CALML4/SLC4A2/CALM3/ADCY9/CHRM3/PRKCB	9
KEGG	hsa05133	Pertussis	9/988	76/8135	0.5853	1	0.8995	ITGA5/CALML4/CASP7/CASP1/C5/IL12A/PYCARD/TRAF6/CALM3	9
KEGG	hsa04530	Tight junction	20/988	169/8135	0.5857	1	0.8995	WHAMM/CDK4/PRKAG2/TUBA1A/ERBB2/PRKAB1/MAP2K7/F11R/CLDN15/TUBA4A/PRKCE/PRKCI/EZR/PARD6G/RAPGEF2/RAB13/ARPC1B/NF2/MYL12A/LLGL2	20
KEGG	hsa05332	Graft-versus-host disease	5/988	42/8135	0.5898	1	0.8995	HLA-DRB1/HLA-DQA1/HLA-E/HLA-DMB/HLA-DMA	5
KEGG	hsa04630	JAK-STAT signaling pathway	19/988	162/8135	0.6017	1	0.8995	CISH/PIM1/PTPN6/PIK3CA/CREBBP/RAF1/GH1/IL20RB/CDKN1A/SOCS4/PDGFA/MTOR/SOS1/PIK3CB/PIK3CD/IL12A/SOCS2/STAM/BCL2L1	19
KEGG	hsa04978	Mineral absorption	7/988	60/8135	0.6047	1	0.8995	SLC30A1/FTL/ATP1B2/SLC11A2/MT2A/SLC40A1/HMOX1	7
KEGG	hsa05205	Proteoglycans in cancer	24/988	205/8135	0.6097	1	0.8995	PTPN6/FZD6/PIK3CA/CAMK2D/ITGA5/ERBB2/RAF1/CDKN1A/THBS1/EZR/NUDT16L1/HBEGF/VTN/MTOR/SOS1/PIK3CB/COL1A1/ARHGEF1/HSPG2/RPS6KB2/PIK3CD/CTNNB1/HPSE/PRKCB	24
KEGG	hsa05031	Amphetamine addiction	8/988	69/8135	0.6114	1	0.8995	ATF4/CAMK2D/FOSB/HDAC2/CALML4/CALM3/MAOA/PRKCB	8
KEGG	hsa00071	Fatty acid degradation	5/988	43/8135	0.6115	1	0.8995	CPT2/ECI2/CPT1C/ACAA1/ECHS1	5
KEGG	hsa00790	Folate biosynthesis	3/988	26/8135	0.6275	1	0.8995	TPH1/GCH1/PTS	3
KEGG	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	8/988	70/8135	0.6281	1	0.8995	MAP3K14/NFKBIA/F11R/ATP6V1G1/ATP6V1E1/HBEGF/ATP6V0E1/ATP6V0C	8
KEGG	hsa04371	Apelin signaling pathway	16/988	139/8135	0.6306	1	0.8995	PRKAG2/MEF2D/NRF1/PIK3R5/RAF1/PRKAB1/HDAC4/PRKCE/CALML4/MTOR/KLF2/RPS6KB2/SPHK2/CALM3/ADCY9/LIPE	16
KEGG	hsa03015	mRNA surveillance pathway	11/988	97/8135	0.6432	1	0.8995	UPF1/DDX19B/CLP1/SMG6/CPSF1/PELO/NXT1/SAP18/SMG5/UPF2/MSI2	11
KEGG	hsa04510	Focal adhesion	23/988	201/8135	0.6539	1	0.8995	MYL5/PIK3CA/ITGA5/ERBB2/RAF1/ITGA10/ITGA3/PDGFA/THBS3/THBS1/PIP5K1A/RAC2/VTN/SOS1/PIK3CB/COL1A1/COL6A2/PIK3CD/CTNNB1/PIP5K1C/FLT4/MYL12A/PRKCB	23
KEGG	hsa04151	PI3K-Akt signaling pathway	41/988	354/8135	0.655	1	0.8995	ATF4/CDK4/LPAR3/PIK3CA/PIK3R5/LPAR2/PHLPP1/MTCP1/ITGA5/ERBB2/RAF1/TSC1/GH1/ITGA10/TGFA/ITGA3/CDKN1A/NGFR/PDGFA/THBS3/TSC2/EFNA4/THBS1/CASP9/PKN2/CRTC2/VTN/MTOR/SOS1/PIK3CB/COL1A1/COL6A2/CDKN1B/RPS6KB2/PIK3CD/NTRK1/BCL2L1/YWHAE/RPTOR/FLT4/PKN3	41
KEGG	hsa00564	Glycerophospholipid metabolism	11/988	98/8135	0.6569	1	0.8995	ETNK1/ETNK2/LCAT/DGKZ/MBOAT7/AGPAT4/AGPAT3/AGPAT1/PEMT/PLA2G4C/GPAT2	11
KEGG	hsa00310	Lysine degradation	7/988	63/8135	0.6573	1	0.8995	ASH1L/EHMT2/DLST/NSD1/CAMKMT/SETD1B/ECHS1	7
KEGG	hsa05217	Basal cell carcinoma	7/988	63/8135	0.6573	1	0.8995	FZD6/CDKN1A/DDB2/BAK1/CTNNB1/BMP4/TCF7L2	7
KEGG	hsa05202	Transcriptional misregulation in cancer	22/988	193/8135	0.6592	1	0.8995	CCNT1/BCL6/ZBTB17/TAF15/KDM6A/CDKN1A/NGFR/PDGFA/HDAC2/ETV7/REL/LDB1/DDB2/BAK1/RXRB/CDKN1B/NTRK1/BCL2L1/KLF3/PML/DDIT3/DUSP6	22
KEGG	hsa03050	Proteasome	5/988	46/8135	0.6722	1	0.8995	PSMA5/PSMD7/PSMD6/PSME4/PSMC2	5
KEGG	hsa04146	Peroxisome	9/988	82/8135	0.6782	1	0.8995	PEX10/PEX12/PEX6/PEX16/ECI2/PXMP2/PEX26/ACAA1/PEX7	9
KEGG	hsa05020	Prion disease	31/988	273/8135	0.6857	1	0.8995	ATF4/STIP1/TUBA1A/PIK3CA/PPIF/HSPA1L/NDUFA11/HSPA1A/PRNP/NDUFS1/PSMA5/TUBB6/NDUFA7/TUBA4A/CASP9/PSMD7/RAC2/PSMD6/PIK3CB/C5/TUBB4B/PIK3CD/COX5B/HSPA8/C8G/PSMC2/TUBB2A/KLC1/DDIT3/NDUFS7/COX8A	31
KEGG	hsa05321	Inflammatory bowel disease	7/988	65/8135	0.6899	1	0.8995	HLA-DRB1/HLA-DQA1/HLA-DMB/HLA-DMA/IL17A/IL12A/RORA	7
KEGG	hsa04916	Melanogenesis	11/988	101/8135	0.6963	1	0.8995	FZD6/CREBBP/CAMK2D/RAF1/CALML4/MC1R/CTNNB1/TCF7L2/CALM3/ADCY9/PRKCB	11
KEGG	hsa04935	Growth hormone synthesis, secretion and action	13/988	119/8135	0.7009	1	0.8995	ATF4/PIK3CA/CREBBP/RAF1/GH1/MTOR/SOS1/PIK3CB/PIK3CD/MAP2K6/SOCS2/ADCY9/PRKCB	13
KEGG	hsa04392	Hippo signaling pathway - multiple species	3/988	29/8135	0.7017	1	0.8995	NF2/CSNK1E/WWTR1	3
KEGG	hsa04744	Phototransduction	3/988	29/8135	0.7017	1	0.8995	CALML4/RCVRN/CALM3	3
KEGG	hsa05323	Rheumatoid arthritis	10/988	93/8135	0.7073	1	0.8995	HLA-DRB1/HLA-DQA1/ATP6V1G1/ATP6V1E1/HLA-DMB/HLA-DMA/ATP6V0E1/IL17A/CTSK/ATP6V0C	10
KEGG	hsa04914	Progesterone-mediated oocyte maturation	11/988	102/8135	0.7088	1	0.8995	PIK3CA/ANAPC7/FZR1/RAF1/KIF22/PIK3CB/RPS6KA1/PIK3CD/ANAPC2/AURKA/ADCY9	11
KEGG	hsa04932	Non-alcoholic fatty liver disease	17/988	155/8135	0.7111	1	0.8995	ATF4/PRKAG2/PIK3CA/NDUFA11/PRKAB1/GSK3A/NDUFS1/NDUFA7/CASP7/PIK3CB/ADIPOR1/PIK3CD/COX5B/DDIT3/NDUFS7/COX8A/ERN1	17
KEGG	hsa04350	TGF-beta signaling pathway	10/988	94/8135	0.72	1	0.8995	TGIF2/CREBBP/SMURF1/ID1/THBS1/CDKN2B/RPS6KB2/BMP8B/SMAD7/BMP4	10
KEGG	hsa00630	Glyoxylate and dicarboxylate metabolism	3/988	30/8135	0.7238	1	0.8995	AMT/GLYCTK/GRHPR	3
KEGG	hsa04810	Regulation of actin cytoskeleton	24/988	218/8135	0.729	1	0.8995	MYL5/PIK3CA/LPAR2/CXCR4/ITGA5/RAF1/ITGA10/ITGA3/PDGFA/EZR/PIP5K1A/RAC2/SOS1/PIK3CB/ARHGEF1/WASL/CHRM4/ARPC1B/PIK3CD/PIP5K1C/FGD3/MYL12A/LIMK1/CHRM3	24
KEGG	hsa04390	Hippo signaling pathway	17/988	157/8135	0.7308	1	0.8995	FZD6/ID1/BTRC/PRKCI/PARD6G/FBXW11/NF2/BMP8B/CSNK1E/CTNNB1/SMAD7/BMP4/CSNK1D/TCF7L2/YWHAE/WWTR1/LLGL2	17
KEGG	hsa04979	Cholesterol metabolism	5/988	50/8135	0.7428	1	0.8995	LRPAP1/NCEH1/LCAT/LIPC/MYLIP	5
KEGG	hsa05144	Malaria	5/988	50/8135	0.7428	1	0.8995	CR1/THBS3/THBS1/IL12A/HBB	5
KEGG	hsa05150	Staphylococcus aureus infection	10/988	96/8135	0.7444	1	0.8995	HLA-DRB1/HLA-DQA1/HLA-DMB/C5/KRT17/HLA-DMA/FCGR2B/KRT20/FCGR2C/FPR1	10
KEGG	hsa00410	beta-Alanine metabolism	3/988	31/8135	0.7446	1	0.8995	ECHS1/SMOX/ABAT	3
KEGG	hsa04217	Necroptosis	17/988	159/8135	0.7496	1	0.8995	SPATA2/CFLAR/TNFRSF10B/TNFAIP3/FADD/CAMK2D/CHMP1B/FAF1/FTL/SHARPIN/SQSTM1/CASP1/TNFSF10/PYGM/PYCARD/PLA2G4C/PYGL	17
KEGG	hsa04611	Platelet activation	13/988	124/8135	0.7555	1	0.8995	PIK3CA/PIK3R5/PRKCI/PIK3CB/COL1A1/ARHGEF1/PIK3CD/PTGS1/FERMT3/P2RY12/ADCY9/PLA2G4C/MYL12A	13
KEGG	hsa04512	ECM-receptor interaction	9/988	88/8135	0.7573	1	0.8995	ITGA5/ITGA10/ITGA3/THBS3/THBS1/VTN/COL1A1/HSPG2/COL6A2	9
KEGG	hsa00340	Histidine metabolism	2/988	22/8135	0.7663	1	0.8995	HAL/MAOA	2
KEGG	hsa00900	Terpenoid backbone biosynthesis	2/988	22/8135	0.7663	1	0.8995	RCE1/MVD	2
KEGG	hsa00380	Tryptophan metabolism	4/988	42/8135	0.7678	1	0.8995	DLST/TPH1/ECHS1/MAOA	4
KEGG	hsa04014	Ras signaling pathway	25/988	232/8135	0.7701	1	0.8995	PIK3CA/RAF1/RASA3/TGFA/NGFR/PDGFA/RASA4/REL/EFNA4/RAC2/CALML4/SOS1/RALB/PIK3CB/NF1/ZAP70/PIK3CD/NTRK1/SYNGAP1/BCL2L1/KSR1/FLT4/CALM3/PLA2G4C/PRKCB	25
KEGG	hsa04640	Hematopoietic cell lineage	10/988	99/8135	0.7782	1	0.8995	HLA-DRB1/HLA-DQA1/ITGA5/CR1/ITGA3/CD7/HLA-DMB/TFRC/HLA-DMA/CD55	10
KEGG	hsa04921	Oxytocin signaling pathway	16/988	154/8135	0.7843	1	0.8995	PRKAG2/NFATC2/PIK3R5/CAMK2D/RAF1/PRKAB1/CDKN1A/NFATC3/CALML4/CACNA2D2/MAP2K5/CAMK1D/CALM3/ADCY9/PLA2G4C/PRKCB	16
KEGG	hsa03060	Protein export	2/988	23/8135	0.7877	1	0.8995	SEC61A2/SPCS2	2
KEGG	hsa04961	Endocrine and other factor-regulated calcium reabsorption	5/988	53/8135	0.788	1	0.8995	DNM2/AP2S1/ATP1B2/ADCY9/PRKCB	5
KEGG	hsa05320	Autoimmune thyroid disease	5/988	53/8135	0.788	1	0.8995	HLA-DRB1/HLA-DQA1/HLA-E/HLA-DMB/HLA-DMA	5
KEGG	hsa04933	AGE-RAGE signaling pathway in diabetic complications	10/988	100/8135	0.7888	1	0.8995	PIM1/CDK4/PIK3CA/PRKCE/PIK3CB/COL1A1/CDKN1B/PIK3CD/PLCD1/PRKCB	10
KEGG	hsa04977	Vitamin digestion and absorption	2/988	24/8135	0.8074	1	0.8995	MMACHC/ABCC1	2
KEGG	hsa05142	Chagas disease	10/988	102/8135	0.8087	1	0.8995	CFLAR/PIK3CA/FADD/NFKBIA/CD247/PIK3CB/GNAL/PIK3CD/IL12A/TRAF6	10
KEGG	hsa04970	Salivary secretion	9/988	93/8135	0.812	1	0.8995	ATP1B2/BST1/CALML4/SLC4A2/CALM3/ADCY9/PRH1/CHRM3/PRKCB	9
KEGG	hsa04022	cGMP-PKG signaling pathway	17/988	167/8135	0.8161	1	0.8995	ATF4/NFATC2/MEF2D/PPIF/PIK3R5/GTF2I/RAF1/PRKCE/ADRA2B/ATP1B2/NFATC3/SRF/ATP2A3/CALML4/PDE2A/CALM3/ADCY9	17
KEGG	hsa04310	Wnt signaling pathway	17/988	167/8135	0.8161	1	0.8995	NFATC2/FZD6/CREBBP/CAMK2D/BTRC/NFATC3/SENP2/RAC2/MAP3K7/ROR2/FBXW11/FRAT1/CSNK1E/CTNNB1/CBY1/TCF7L2/PRKCB	17
KEGG	hsa04725	Cholinergic synapse	11/988	113/8135	0.8242	1	0.8995	ATF4/PIK3CA/PIK3R5/CAMK2D/PIK3CB/CHRM4/PIK3CD/ADCY9/KCNQ4/CHRM3/PRKCB	11
KEGG	hsa00592	alpha-Linolenic acid metabolism	2/988	25/8135	0.8254	1	0.8995	ACAA1/PLA2G4C	2
KEGG	hsa04610	Complement and coagulation cascades	8/988	85/8135	0.8262	1	0.8995	CD46/CR1/VTN/PROS1/C5/CD55/C8G/SERPINF2	8
KEGG	hsa00350	Tyrosine metabolism	3/988	36/8135	0.8303	1	0.8995	FAHD1/FAH/MAOA	3
KEGG	hsa00512	Mucin type O-glycan biosynthesis	3/988	36/8135	0.8303	1	0.8995	GALNT3/GALNT10/C1GALT1C1	3
KEGG	hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	1/988	14/8135	0.837	1	0.8995	B3GNT2	1
KEGG	hsa00620	Pyruvate metabolism	4/988	47/8135	0.8393	1	0.8995	PDHA1/ACYP1/GRHPR/HAGH	4
KEGG	hsa00010	Glycolysis / Gluconeogenesis	6/988	67/8135	0.8395	1	0.8995	PDHA1/PGAM4/HKDC1/ALDOA/ENO2/HK1	6
KEGG	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	7/988	77/8135	0.8419	1	0.8995	ITGA5/ITGA10/ITGA3/ATP2A3/CTNNB1/CACNA2D2/TCF7L2	7
KEGG	hsa00250	Alanine, aspartate and glutamate metabolism	3/988	37/8135	0.8441	1	0.8995	ASS1/GLS/ABAT	3
KEGG	hsa00280	Valine, leucine and isoleucine degradation	4/988	48/8135	0.8511	1	0.8995	OXCT2/ACAA1/ECHS1/ABAT	4
KEGG	hsa04360	Axon guidance	18/988	182/8135	0.8557	1	0.8995	MYL5/NFATC2/PIK3CA/CAMK2D/CXCR4/SEMA4C/RAF1/LRIG2/EFNA4/NFATC3/RAC2/PARD6G/PIK3CB/PIK3CD/SEMA4F/CDK5/MYL12A/LIMK1	18
KEGG	hsa00730	Thiamine metabolism	1/988	15/8135	0.8569	1	0.8995	AK1	1
KEGG	hsa05340	Primary immunodeficiency	3/988	38/8135	0.857	1	0.8995	ZAP70/TAP1/AIRE	3
KEGG	hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	2/988	27/8135	0.857	1	0.8995	B3GNT2/ABO	2
KEGG	hsa05030	Cocaine addiction	4/988	49/8135	0.8622	1	0.8995	ATF4/FOSB/CDK5/MAOA	4
KEGG	hsa05206	MicroRNAs in cancer	32/988	310/8135	0.8633	1	0.8995	PIM1/PIK3CA/CREBBP/SLC7A1/ITGA5/ERBB2/RAF1/HDAC4/CDKN1A/PDGFA/PRKCE/DICER1/HDAC2/RPS6KA5/EFNA4/THBS1/BMF/EZR/MTOR/SOS1/PIK3CB/BAK1/ABCC1/CDKN1B/ZEB2/PIK3CD/CCNG1/GLS/CDCA5/RPTOR/HMOX1/PRKCB	32
KEGG	hsa00513	Various types of N-glycan biosynthesis	3/988	39/8135	0.8689	1	0.8995	MAN1A2/MAN2A2/ALG2	3
KEGG	hsa04071	Sphingolipid signaling pathway	11/988	119/8135	0.8706	1	0.8995	PIK3CA/S1PR4/RAF1/PRKCE/S1PR5/RAC2/PIK3CB/ABCC1/PIK3CD/SPHK2/PRKCB	11
KEGG	hsa05415	Diabetic cardiomyopathy	20/988	203/8135	0.8708	1	0.8995	PDHA1/PIK3CA/PPIF/CAMK2D/NDUFA11/CPT2/NDUFS1/SLC2A1/NDUFA7/ATP2A3/RAC2/MTOR/PIK3CB/COL1A1/MPC1/PIK3CD/COX5B/NDUFS7/PRKCB/COX8A	20
KEGG	hsa04926	Relaxin signaling pathway	12/988	129/8135	0.8738	1	0.8995	ATF4/PIK3CA/RAF1/NFKBIA/MAP2K7/SOS1/PIK3CB/COL1A1/ARRB1/PIK3CD/ARRB2/ADCY9	12
KEGG	hsa00360	Phenylalanine metabolism	1/988	16/8135	0.8743	1	0.8995	MAOA	1
KEGG	hsa00140	Steroid hormone biosynthesis	5/988	61/8135	0.8784	1	0.8995	AKR1C2/HSD11B1/AKR1C1/SULT2B1/CYP17A1	5
KEGG	hsa00270	Cysteine and methionine metabolism	4/988	51/8135	0.8823	1	0.8995	MAT2A/AMD1/APIP/SDSL	4
KEGG	hsa00330	Arginine and proline metabolism	4/988	51/8135	0.8823	1	0.8995	ODC1/AMD1/MAOA/SMOX	4
KEGG	hsa00450	Selenocompound metabolism	1/988	17/8135	0.8896	1	0.8995	SEPSECS	1
KEGG	hsa00910	Nitrogen metabolism	1/988	17/8135	0.8896	1	0.8995	CA4	1
KEGG	hsa04728	Dopaminergic synapse	12/988	132/8135	0.8921	1	0.8995	ATF4/CAMK2D/GSK3A/CALML4/ARNTL/GNAL/ARRB1/ARRB2/CALM3/MAOA/PRKCB/DRD3	12
KEGG	hsa01523	Antifolate resistance	2/988	30/8135	0.8946	1	0.8995	GART/ABCC1	2
KEGG	hsa04613	Neutrophil extracellular trap formation	18/988	190/8135	0.8983	1	0.8995	PIK3CA/PPIF/RAF1/HDAC4/CR1/AZU1/HDAC2/RAC2/MAP3K7/MTOR/PIK3CB/CASP1/C5/GSDMD/PIK3CD/HDAC7/PRKCB/FPR1	18
KEGG	hsa01240	Biosynthesis of cofactors	14/988	153/8135	0.902	1	0.8995	VKORC1/MAT2A/RDH11/VKORC1L1/DHRS3/ASPDH/GCH1/UGDH/GMPPB/NME6/PPCDC/AK1/LIPT1/PTS	14
KEGG	hsa04270	Vascular smooth muscle contraction	12/988	134/8135	0.903	1	0.8995	RAF1/PRKCQ/PRKCE/PRKCH/CALML4/ARHGEF1/RAMP3/EDN2/CALM3/ADCY9/PLA2G4C/PRKCB	12
KEGG	hsa00061	Fatty acid biosynthesis	1/988	18/8135	0.903	1	0.8995	MECR	1
KEGG	hsa00511	Other glycan degradation	1/988	18/8135	0.903	1	0.8995	MAN2C1	1
KEGG	hsa00052	Galactose metabolism	2/988	31/8135	0.905	1	0.8995	HKDC1/HK1	2
KEGG	hsa04911	Insulin secretion	7/988	86/8135	0.9112	1	0.8995	ATF4/CAMK2D/SLC2A1/ATP1B2/ADCY9/CHRM3/PRKCB	7
KEGG	hsa01210	2-Oxocarboxylic acid metabolism	1/988	19/8135	0.9148	1	0.8995	NAGS	1
KEGG	hsa05208	Chemical carcinogenesis - reactive oxygen species	21/988	223/8135	0.9184	1	0.8995	PIK3CA/PPIF/MAP3K14/RAF1/PTPN1/NDUFA11/NFKBIA/NDUFS1/MAP2K7/NDUFA7/AKR1C2/SOS1/PIK3CB/PIK3CD/NFE2L2/COX5B/AKR1C1/GSTM4/HMOX1/NDUFS7/COX8A	21
KEGG	hsa04721	Synaptic vesicle cycle	6/988	78/8135	0.9247	1	0.8995	DNM2/ATP6V1G1/AP2S1/ATP6V1E1/ATP6V0E1/ATP6V0C	6
KEGG	hsa00100	Steroid biosynthesis	1/988	20/8135	0.9252	1	0.8995	LSS	1
KEGG	hsa00040	Pentose and glucuronate interconversions	2/988	34/8135	0.9306	1	0.8995	RPE/UGDH	2
KEGG	hsa05410	Hypertrophic cardiomyopathy	7/988	90/8135	0.9324	1	0.8995	PRKAG2/ITGA5/PRKAB1/ITGA10/ITGA3/ATP2A3/CACNA2D2	7
KEGG	hsa04924	Renin secretion	5/988	69/8135	0.9337	1	0.8995	PTGER4/CALML4/AQP1/EDN2/CALM3	5
KEGG	hsa04114	Oocyte meiosis	11/988	131/8135	0.9339	1	0.8995	ANAPC7/CAMK2D/BTRC/CALML4/FBXW11/RPS6KA1/ANAPC2/AURKA/YWHAE/CALM3/ADCY9	11
KEGG	hsa00770	Pantothenate and CoA biosynthesis	1/988	21/8135	0.9343	1	0.8995	PPCDC	1
KEGG	hsa04972	Pancreatic secretion	8/988	102/8135	0.9395	1	0.8995	CTRL/ATP1B2/BST1/ATP2A3/SLC4A2/ADCY9/CHRM3/PRKCB	8
KEGG	hsa05146	Amoebiasis	8/988	102/8135	0.9395	1	0.8995	PIK3CA/PIK3CB/COL1A1/GNAL/PIK3CD/IL12A/C8G/PRKCB	8
KEGG	hsa04062	Chemokine signaling pathway	17/988	192/8135	0.9415	1	0.8995	ITK/PIK3CA/PIK3R5/CXCR4/RAF1/NFKBIA/GSK3A/NFKBIB/RAC2/SOS1/PIK3CB/ARRB1/PIK3CD/ELMO1/ARRB2/ADCY9/PRKCB	17
KEGG	hsa04974	Protein digestion and absorption	8/988	103/8135	0.9435	1	0.8995	SLC3A2/CTRL/SLC3A1/ATP1B2/COL1A1/COL27A1/COL6A2/SLC7A9	8
KEGG	hsa00190	Oxidative phosphorylation	11/988	134/8135	0.9448	1	0.8995	NDUFA11/NDUFS1/NDUFA7/ATP6V1G1/ATP6V1E1/ATP6V0E1/PPA1/COX5B/ATP6V0C/NDUFS7/COX8A	11
KEGG	hsa05171	Coronavirus disease - COVID-19	21/988	232/8135	0.946	1	0.8995	PIK3CA/ISG15/DDX58/RPL36AL/OAS2/NFKBIA/NFKBIB/TRAF3/RPS26/HBEGF/MAP3K7/PIK3CB/CASP1/C5/PIK3CD/IL12A/TRAF6/C8G/RPS7/RPS27/PRKCB	21
KEGG	hsa04934	Cushing syndrome	13/988	155/8135	0.9479	1	0.8995	ATF4/CDK4/FZD6/NCEH1/AIP/CAMK2D/CDKN1A/CDKN1B/CDKN2B/CTNNB1/TCF7L2/ADCY9/CYP17A1	13
KEGG	hsa00590	Arachidonic acid metabolism	4/988	61/8135	0.9488	1	0.8995	GGT1/ALOX5/PTGS1/PLA2G4C	4
KEGG	hsa04614	Renin-angiotensin system	1/988	23/8135	0.9493	1	0.8995	CTSA	1
KEGG	hsa04726	Serotonergic synapse	9/988	115/8135	0.9493	1	0.8995	RAF1/DUSP1/TPH1/CYP2D6/ALOX5/PTGS1/MAOA/PLA2G4C/PRKCB	9
KEGG	hsa03320	PPAR signaling pathway	5/988	75/8135	0.9591	1	0.8995	CPT2/GK/CPT1C/RXRB/ACAA1	5
KEGG	hsa04713	Circadian entrainment	7/988	97/8135	0.9591	1	0.8995	PER1/CAMK2D/RPS6KA5/CALML4/CALM3/ADCY9/PRKCB	7
KEGG	hsa00600	Sphingolipid metabolism	3/988	52/8135	0.9605	1	0.8995	KDSR/B4GALT6/SPHK2	3
KEGG	hsa04927	Cortisol synthesis and secretion	4/988	65/8135	0.964	1	0.8995	ATF4/NCEH1/ADCY9/CYP17A1	4
KEGG	hsa05207	Chemical carcinogenesis - receptor activation	18/988	212/8135	0.9657	1	0.8995	ATF4/PIK3CA/AIP/KPNA5/BCL6/RAF1/MTOR/SOS1/PIK3CB/ARRB1/RPS6KA1/RXRB/RPS6KB2/PIK3CD/GSTM4/ARRB2/ADCY9/PRKCB	18
KEGG	hsa00970	Aminoacyl-tRNA biosynthesis	4/988	66/8135	0.9671	1	0.8995	DARS2/SARS2/CARS2/SEPSECS	4
KEGG	hsa04727	GABAergic synapse	6/988	89/8135	0.9673	1	0.8995	SLC38A1/GABARAPL1/GLS/ADCY9/PRKCB/ABAT	6
KEGG	hsa04976	Bile secretion	6/988	89/8135	0.9673	1	0.8995	NCEH1/SLC2A1/ATP1B2/AQP1/SLC4A2/ADCY9	6
KEGG	hsa00980	Metabolism of xenobiotics by cytochrome P450	5/988	78/8135	0.9681	1	0.8995	AKR7A3/CYP2D6/HSD11B1/AKR1C1/GSTM4	5
KEGG	hsa00591	Linoleic acid metabolism	1/988	29/8135	0.9768	1	0.8995	PLA2G4C	1
KEGG	hsa00480	Glutathione metabolism	3/988	58/8135	0.9781	1	0.8995	ODC1/GGT1/GSTM4	3
KEGG	hsa04514	Cell adhesion molecules	11/988	149/8135	0.9788	1	0.8995	HLA-DRB1/HLA-DQA1/NLGN3/HLA-E/F11R/CLDN15/HLA-DMB/HLA-DMA/CDH3/ICAM3/ICAM2	11
KEGG	hsa02010	ABC transporters	2/988	45/8135	0.979	1	0.8995	ABCC1/TAP1	2
KEGG	hsa00053	Ascorbate and aldarate metabolism	1/988	30/8135	0.9796	1	0.8995	UGDH	1
KEGG	hsa00982	Drug metabolism - cytochrome P450	4/988	72/8135	0.981	1	0.8995	CYP2D6/FMO4/GSTM4/MAOA	4
KEGG	hsa05414	Dilated cardiomyopathy	6/988	96/8135	0.9814	1	0.8995	ITGA5/ITGA10/ITGA3/ATP2A3/CACNA2D2/ADCY9	6
KEGG	hsa04730	Long-term depression	3/988	60/8135	0.9821	1	0.8995	RAF1/PLA2G4C/PRKCB	3
KEGG	hsa04550	Signaling pathways regulating pluripotency of stem cells	10/988	143/8135	0.9847	1	0.8995	FZD6/PIK3CA/RAF1/ID1/PCGF1/PIK3CB/PIK3CD/CTNNB1/JARID2/BMP4	10
KEGG	hsa04260	Cardiac muscle contraction	5/988	87/8135	0.9853	1	0.8995	ATP1B2/ATP2A3/CACNA2D2/COX5B/COX8A	5
KEGG	hsa04918	Thyroid hormone synthesis	4/988	75/8135	0.9856	1	0.8995	ATF4/ATP1B2/ADCY9/PRKCB	4
KEGG	hsa00565	Ether lipid metabolism	2/988	49/8135	0.9865	1	0.8995	PAFAH1B3/PLA2G4C	2
KEGG	hsa04020	Calcium signaling pathway	19/988	240/8135	0.9875	1	0.8995	PPIF/P2RX7/CAMK2D/CXCR4/ERBB2/PDGFA/ATP2A3/CALML4/MCOLN3/GNAL/NTRK1/PLCD1/SPHK2/CAMK1D/FLT4/CALM3/ADCY9/CHRM3/PRKCB	19
KEGG	hsa04024	cAMP signaling pathway	17/988	221/8135	0.9885	1	0.8995	PIK3CA/CREBBP/CAMK2D/RAF1/NFKBIA/HCN2/ATP1B2/ATP2A3/RAC2/CALML4/PIK3CB/EDN2/FFAR2/PIK3CD/CALM3/ADCY9/LIPE	17
KEGG	hsa05032	Morphine addiction	5/988	91/8135	0.9897	1	0.8995	ARRB1/PDE2A/ARRB2/ADCY9/PRKCB	5
KEGG	hsa04261	Adrenergic signaling in cardiomyocytes	10/988	150/8135	0.9908	1	0.8995	ATF4/PIK3R5/CAMK2D/RPS6KA5/ATP1B2/ATP2A3/CALML4/CACNA2D2/CALM3/ADCY9	10
KEGG	hsa05204	Chemical carcinogenesis - DNA adducts	3/988	69/8135	0.9929	1	0.8995	AKR1C2/HSD11B1/GSTM4	3
KEGG	hsa03010	Ribosome	10/988	158/8135	0.9949	1	0.8995	MRPS2/RPL36AL/MRPL10/MRPS18A/MRPS5/MRPL32/RPS26/MRPL24/RPS7/RPS27	10
KEGG	hsa04061	Viral protein interaction with cytokine and cytokine receptor	5/988	100/8135	0.9955	1	0.8995	IL34/TNFRSF10B/CXCR4/IL20RB/TNFSF10	5
KEGG	hsa00860	Porphyrin metabolism	1/988	43/8135	0.9962	1	0.8995	HMOX1	1
KEGG	hsa04975	Fat digestion and absorption	1/988	43/8135	0.9962	1	0.8995	AGPAT1	1
KEGG	hsa00983	Drug metabolism - other enzymes	3/988	80/8135	0.9978	1	0.8995	CES2/NME6/GSTM4	3
KEGG	hsa05322	Systemic lupus erythematosus	7/988	136/8135	0.9983	1	0.8995	HLA-DRB1/HLA-DQA1/HLA-DMB/SNRPB/C5/HLA-DMA/C8G	7
KEGG	hsa00830	Retinol metabolism	2/988	68/8135	0.9985	1	0.8995	RDH11/DHRS3	2
KEGG	hsa04724	Glutamatergic synapse	5/988	114/8135	0.9988	1	0.8995	SLC38A1/GLS/ADCY9/PLA2G4C/PRKCB	5
KEGG	hsa04742	Taste transduction	3/988	86/8135	0.9988	1	0.8995	TAS2R9/CHRM3/TAS2R42	3
KEGG	hsa04723	Retrograde endocannabinoid signaling	7/988	148/8135	0.9994	1	0.8995	NDUFA11/NAPEPLD/NDUFS1/NDUFA7/ADCY9/NDUFS7/PRKCB	7
KEGG	hsa05034	Alcoholism	10/988	187/8135	0.9995	1	0.8995	ATF4/RAF1/FOSB/HDAC4/HDAC2/CALML4/SOS1/CALM3/MAOA/HDAC7	10
KEGG	hsa04060	Cytokine-cytokine receptor interaction	15/988	295/8135	1	1	0.8995	IL34/TNFRSF10B/CXCR4/RELT/CD27/GH1/IL20RB/IL17C/NGFR/TNFSF10/TNFRSF6B/IL17A/BMP8B/IL12A/BMP4	15
KEGG	hsa04080	Neuroactive ligand-receptor interaction	19/988	353/8135	1	1	0.8995	NR3C1/PTGER4/LPAR3/P2RX7/S1PR4/LPAR2/P2RY8/GH1/GNRH1/ADRA2B/S1PR5/C5/EDN2/CHRM4/MC1R/F2RL1/CHRM3/FPR1/DRD3	19
KEGG	hsa04740	Olfactory transduction	24/988	440/8135	1	1	0.8995	CAMK2D/OR2T3/CALML4/OR52N1/GNAL/ARRB1/OR2B11/OR2A1/OR2M5/OR13C2/OR10A6/PDE2A/OR5C1/OR2A2/OR2L8/OR10C1/OR5D13/ARRB2/CALM3/OR13F1/OR56A4/OR10J1/OR1A1/OR6M1	24