ONTOLOGY	ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	qvalue	geneID	Count
BP	GO:0009451	RNA modification	36/1616	163/18670	1.258e-07	0.0007286	0.0006758	C9orf64/ELP5/NOP10/RPUSD2/WTAP/DUS3L/PCIF1/FDXACB1/TRMT112/PUSL1/TFB1M/THUMPD1/RBM47/NSUN4/NSUN5P2/RPUSD3/METTL16/TRMT10C/PUS1/RRNAD1/OSGEP/TRUB1/AICDA/TRMT5/TRMT13/TFB2M/FTO/TGS1/TRMU/ALKBH8/NSUN2/THUMPD2/DPH3P1/CDK5RAP1/CTU1/PUS3	36
BP	GO:0009615	response to virus	56/1616	326/18670	5.246e-07	0.001075	0.0009967	CCT5/IRF7/PIM2/GBP1/SERINC3/IFITM2/IRF2/IKBKB/PPM1B/HYAL3/ZNF175/ISG15/ZC3H12A/PYCARD/CXCR4/IFIT1/TNFAIP3/RSAD2/ANKRD17/MUL1/DTX3L/UNC93B1/OAS2/AZU1/MAP3K14/MAPK11/FADD/EXOSC5/TRIM11/BNIP3/BCL2L1/BST2/ZCCHC3/IL12A/RNF26/AICDA/IFITM1/IFITM3/GPATCH3/LGALS9/CFL1/PSMA2/RNF125/MICA/HNRNPUL1/MST1R/IRGM/MICB/PQBP1/IFNA10/SKP2/EIF2AK4/DDX58/TSPAN32/OAS1/ISG20	56
BP	GO:0034470	ncRNA processing	63/1616	384/18670	5.565e-07	0.001075	0.0009967	C9orf64/ELP5/NOP10/RPP14/CLP1/GTF2H5/WDR46/RPUSD2/BYSL/TSEN15/ABT1/DUS3L/FDXACB1/TRMT112/PUSL1/PA2G4/POP1/TFB1M/THUMPD1/NSUN4/C2orf49/NSUN5P2/WDR75/DICER1/METTL16/TRMT10C/EXOSC5/PUS1/FAM98B/SRRT/RRNAD1/TBL3/DIS3/TRPT1/OSGEP/TRUB1/MRPL44/TRMT5/NOL9/TRMT13/DDX54/TFB2M/TOE1/KRR1/FAM207A/INTS12/TRMU/DDX24/UTP15/MRTO4/RPP40/ALKBH8/NSUN2/SBDS/THUMPD2/ISG20/UTP23/DPH3P1/CDK5RAP1/CTU1/SIRT1/C1D/PUS3	63
BP	GO:0030522	intracellular receptor signaling pathway	49/1616	280/18670	1.532e-06	0.002219	0.002058	PIM1/PER1/EGLN2/IRF7/DHRS3/CRY2/PHB/NFKBIA/CARM1/NR4A2/TRAF6/TNFAIP3/NR1D2/ANKRD17/MAP3K7/PAGR1/FKBP4/RHOXF1/RORA/RBM14/RXRB/PARK7/TWIST1/HSPA1A/PRMT2/ZCCHC3/GPAM/GPATCH3/DDX54/THRA/RNF125/ASXL2/IRGM/EP300/RNF4/NR1D1/ASXL1/CRABP2/SAFB2/DNAJA1/SKP2/NR3C1/TP63/UBE3A/DDX58/PMEPA1/DAXX/UFM1/SIRT1	49
BP	GO:0008033	tRNA processing	28/1616	130/18670	5.115e-06	0.005926	0.005496	C9orf64/ELP5/RPP14/CLP1/TSEN15/DUS3L/TRMT112/PUSL1/POP1/THUMPD1/C2orf49/TRMT10C/PUS1/FAM98B/TRPT1/OSGEP/TRUB1/TRMT5/TRMT13/TRMU/RPP40/ALKBH8/NSUN2/THUMPD2/DPH3P1/CDK5RAP1/CTU1/PUS3	28
BP	GO:0051607	defense response to virus	42/1616	238/18670	6.744e-06	0.00596	0.005527	IRF7/GBP1/SERINC3/IFITM2/IRF2/PPM1B/ZNF175/ISG15/ZC3H12A/PYCARD/IFIT1/TNFAIP3/RSAD2/ANKRD17/MUL1/DTX3L/UNC93B1/OAS2/AZU1/MAP3K14/FADD/EXOSC5/TRIM11/BNIP3/BST2/ZCCHC3/RNF26/AICDA/IFITM1/IFITM3/GPATCH3/RNF125/MICA/MICB/PQBP1/IFNA10/SKP2/EIF2AK4/DDX58/TSPAN32/OAS1/ISG20	42
BP	GO:0043401	steroid hormone mediated signaling pathway	35/1616	184/18670	7.202e-06	0.00596	0.005527	PER1/EGLN2/CRY2/PHB/CARM1/NR4A2/NR1D2/NR3C2/PAGR1/FKBP4/RHOXF1/RORA/RBM14/RXRB/PARK7/CREBRF/BMP4/PRMT2/GPAM/DDX54/THRA/EP300/PAQR7/RNF4/NR1D1/SAFB2/DNAJA1/SKP2/NR3C1/TP63/UBE3A/PMEPA1/DAXX/UFM1/SIRT1	35
BP	GO:0031331	positive regulation of cellular catabolic process	56/1616	361/18670	1.306e-05	0.009458	0.008771	ENDOG/PIM2/ZC3H12A/SOCS4/PNPLA2/TNFAIP3/NFE2L2/MUL1/SUPV3L1/DTX3L/SH3GLB1/TRIB3/MAP3K7/ZFAND2A/TNRC6B/GSK3A/PARK7/FBXO22/METTL16/CSNK1E/SMCR8/GBA/TWIST1/HSPA1A/CSNK1D/BTG2/SMURF1/BNIP3/ZFP36L1/TMTC3/CEBPA/CCDC22/PFKFB3/FTO/ADAM9/USP5/HERPUD1/GTPBP1/TRIM65/IRGM/ZFP36L2/HK2/YTHDF3/IRS2/VCP/TSC1/CNOT6L/EIF2AK4/UPF1/PFKFB4/HTT/SOCS5/SPTLC2/KCNE2/SIRT1/ENTPD5	56
BP	GO:0033673	negative regulation of kinase activity	43/1616	257/18670	2.064e-05	0.01328	0.01232	PTPN6/DUSP8/RGS14/MVP/PYCARD/MEN1/RASIP1/CSK/SOCS4/SOCS3/TNFAIP3/DUSP1/TRIB3/CEACAM1/PRDX3/PRKAG2/PRKRIP1/GMFB/PARK7/CDKN2B/CDKN1B/MBIP/SMCR8/BMP4/GBA/AKT1S1/CDKN2D/SH2B3/CEBPA/GADD45A/TSG101/CBLB/DBNDD2/IRS2/DNAJA1/LATS2/ZGPAT/ADORA2A/DUSP7/SOCS5/CDKN1A/CDK5RAP1/SIRT1	43
BP	GO:0006469	negative regulation of protein kinase activity	40/1616	235/18670	2.64e-05	0.01335	0.01238	PTPN6/DUSP8/RGS14/MVP/PYCARD/MEN1/RASIP1/SOCS4/SOCS3/TNFAIP3/DUSP1/TRIB3/CEACAM1/PRKAG2/PRKRIP1/GMFB/PARK7/CDKN2B/CDKN1B/MBIP/SMCR8/BMP4/GBA/AKT1S1/CDKN2D/SH2B3/CEBPA/GADD45A/TSG101/CBLB/DBNDD2/DNAJA1/LATS2/ZGPAT/ADORA2A/DUSP7/SOCS5/CDKN1A/CDK5RAP1/SIRT1	40
BP	GO:0043254	regulation of protein complex assembly	67/1616	467/18670	2.682e-05	0.01335	0.01238	GTF2H5/SRF/CXCL13/ERCC2/CAMSAP3/PYCARD/JMY/RASIP1/HIP1R/WHAMMP3/INSIG1/SAR1A/WHAMM/ARPC1B/SH3GLB1/PRRT2/VPS18/TPPP3/HAX1/FKBP4/GMFB/RICTOR/PARK7/CDKN1B/SPIRE2/GBA/TWIST1/HSPA1A/BID/P2RY12/TWF2/RPA2/VASP/CAPZB/DDB1/CORO1B/KIF14/G3BP2/GTF2H4/THRA/PRKCE/RANGRF/ATAT1/ANKRA2/RRN3/TWF1/IRGM/EP300/RNF4/TMSB4Y/CORO1A/MECP2/WNT10B/FNIP1/VCP/FCHSD1/PPM1A/WASL/CNOT6L/MPP7/RAF1/BCLAF1/RPA1/PMEPA1/FMN1/NCKAP1/ARPC5	67
BP	GO:0051348	negative regulation of transferase activity	46/1616	285/18670	2.765e-05	0.01335	0.01238	PTPN6/DUSP8/RGS14/MVP/PYCARD/MEN1/RASIP1/CSK/SOCS4/SOCS3/TNFAIP3/DUSP1/DTX3L/TRIB3/CEACAM1/PRDX3/PRKAG2/PRKRIP1/GSK3A/GMFB/PARK7/CDKN2B/EIF4A2/CDKN1B/MBIP/SMCR8/BMP4/GBA/AKT1S1/CDKN2D/SH2B3/CEBPA/GADD45A/TSG101/CBLB/DBNDD2/IRS2/DNAJA1/LATS2/ZGPAT/ADORA2A/DUSP7/SOCS5/CDKN1A/CDK5RAP1/SIRT1	46
BP	GO:0006400	tRNA modification	20/1616	86/18670	3.469e-05	0.01546	0.01434	C9orf64/ELP5/DUS3L/TRMT112/PUSL1/THUMPD1/TRMT10C/PUS1/OSGEP/TRUB1/TRMT5/TRMT13/TRMU/ALKBH8/NSUN2/THUMPD2/DPH3P1/CDK5RAP1/CTU1/PUS3	20
BP	GO:0070646	protein modification by small protein removal	47/1616	299/18670	4.499e-05	0.01731	0.01606	SPATA2/NFKBIA/USP4/MBD5/WDR48/ATXN7/COPS7A/ZC3H12A/TRAF6/ZRANB1/TNFAIP3/POLB/INO80D/MAP3K7/PSME2/USP38/WDR20/ACTL6A/MYC/ENY2/ACTB/PARK7/SIAH2/PSMD5/JOSD1/PSMA5/TFPT/OTUD4/USP42/SENP2/PSMA2/USP5/ASXL2/EP300/PSME4/SENP5/ASXL1/VCP/BAP1/SKP2/FOXK2/PSMB3/DDX58/USP16/YOD1/USP54/PSMD2	47
BP	GO:0046685	response to arsenic-containing substance	11/1616	32/18670	4.603e-05	0.01731	0.01606	ZC3H12A/ZFAND2A/SRRT/RBM4/RNF4/ATF4/VCP/HNRNPA1/DAXX/ALAD/CDKN1A	11
BP	GO:0051188	cofactor biosynthetic process	50/1616	326/18670	5.02e-05	0.01731	0.01606	PSAT1/NUP50/GART/PARP10/HK1/PGAM4/MMACHC/MAT2B/MTHFS/RFK/PDHA1/NFE2L2/PRKAG2/IREB2/CBR4/GCH1/CHAC2/NUP133/COQ10B/DHFR/METTL16/MBIP/ASPDH/AAAS/NUP35/SLC25A38/SRRD/PFKFB3/RSAD1/GALK1/IBA57/PGK2/ACSL3/MAT2A/HK2/CTNS/PFKL/COQ7/MTHFD1L/FOXK2/COQ9/PNPO/PPTC7/PFKFB4/PFKP/DLD/MPC1/ALAD/ENTPD5/SLC11A2	50
BP	GO:0006399	tRNA metabolic process	34/1616	193/18670	5.08e-05	0.01731	0.01606	C9orf64/ELP5/RPP14/CLP1/DALRD3/TSEN15/DUS3L/TRMT112/PUSL1/POP1/THUMPD1/BRF1/C2orf49/SEPSECS/TRMT10C/PUS1/FAM98B/DARS2/TRPT1/OSGEP/TRUB1/TRMT5/TRMT13/GTF3C4/TRMU/WARS2/RPP40/ALKBH8/NSUN2/THUMPD2/DPH3P1/CDK5RAP1/CTU1/PUS3	34
BP	GO:0031334	positive regulation of protein complex assembly	43/1616	268/18670	5.738e-05	0.01847	0.01713	GTF2H5/SRF/CXCL13/ERCC2/PYCARD/JMY/RASIP1/HIP1R/WHAMMP3/WHAMM/ARPC1B/SH3GLB1/TPPP3/GMFB/RICTOR/CDKN1B/SPIRE2/TWIST1/HSPA1A/BID/P2RY12/RPA2/VASP/DDB1/CORO1B/G3BP2/GTF2H4/PRKCE/ATAT1/CORO1A/MECP2/WNT10B/FNIP1/VCP/FCHSD1/WASL/CNOT6L/MPP7/BCLAF1/RPA1/FMN1/NCKAP1/ARPC5	43
BP	GO:0000082	G1/S transition of mitotic cell cycle	44/1616	279/18670	7.176e-05	0.02188	0.02029	CDK4/PTPN6/PIM2/PRMT1/NASP/CARM1/CDK2AP2/ORC6/CHEK2/KLF11/CCND3/BCAT1/DBF4/PRIM1/ANKRD17/MYO16/PSME2/PLCB1/MYC/MNAT1/CDKN2B/DHFR/ACVR1B/CDKN1B/BID/PRMT2/BTG2/RPA2/KLF4/CDKN2D/KIF14/GADD45A/SENP2/EP300/BRD4/TFDP2/RCC1/SKP2/CNOT6L/LATS2/GPR132/RPA1/GFI1/CDKN1A	44
BP	GO:0044843	cell cycle G1/S phase transition	46/1616	298/18670	8.436e-05	0.02254	0.0209	CDK4/PTPN6/PIM2/PRMT1/NASP/CARM1/CDK2AP2/ORC6/CHEK2/KLF11/MEN1/CCND3/BCAT1/DBF4/PRIM1/ANKRD17/MYO16/PAGR1/PSME2/PLCB1/MYC/MNAT1/CDKN2B/DHFR/ACVR1B/CDKN1B/BID/PRMT2/BTG2/RPA2/KLF4/CDKN2D/KIF14/GADD45A/SENP2/EP300/BRD4/TFDP2/RCC1/SKP2/CNOT6L/LATS2/GPR132/RPA1/GFI1/CDKN1A	46
BP	GO:0009896	positive regulation of catabolic process	60/1616	423/18670	9.588e-05	0.02254	0.0209	EGLN2/ENDOG/PIM2/ZC3H12A/SOCS4/PNPLA2/TNFAIP3/NFE2L2/MUL1/SUPV3L1/DTX3L/SH3GLB1/TRIB3/MAP3K7/ZFAND2A/TNRC6B/GSK3A/PARK7/FBXO22/CDKN1B/METTL16/CSNK1E/SMCR8/GBA/TWIST1/HSPA1A/CSNK1D/BTG2/SMURF1/BNIP3/ZFP36L1/DDB1/TMTC3/CEBPA/CCDC22/PFKFB3/PRKCE/FTO/ADAM9/USP5/HERPUD1/GTPBP1/TRIM65/IRGM/ZFP36L2/HK2/YTHDF3/IRS2/VCP/TSC1/CNOT6L/EIF2AK4/UPF1/PFKFB4/HTT/SOCS5/SPTLC2/KCNE2/SIRT1/ENTPD5	60
BP	GO:0031648	protein destabilization	13/1616	46/18670	9.784e-05	0.02254	0.0209	ISOC2/CREBBP/MUL1/CTSH/SENP2/FBXL3/IRGM/EP300/NR1D1/KDM8/CCDC88C/HTT/SIRT1	13
BP	GO:0006352	DNA-templated transcription, initiation	40/1616	249/18670	9.966e-05	0.02254	0.0209	CDK4/CD3EAP/MED26/NOTCH1/NRBF2/GTF2H5/SRF/ERCC2/NR4A2/TAF11/SMARCB1/POLR2D/BRF2/NR1D2/CREBBP/BRF1/NR3C2/POLR2H/RORA/MNAT1/RXRB/TWIST1/TBPL1/GTF2H4/RSF1/THRA/TFB2M/GTF3C4/MED6/RRN3/TAF15/NAT14/NR1D1/MECP2/WNT10B/BAZ2A/TAF13/NR3C1/BCLAF1/CDKN1A	40
BP	GO:0016579	protein deubiquitination	44/1616	283/18670	0.0001006	0.02254	0.0209	SPATA2/NFKBIA/USP4/MBD5/WDR48/ATXN7/ZC3H12A/TRAF6/ZRANB1/TNFAIP3/POLB/INO80D/MAP3K7/PSME2/USP38/WDR20/ACTL6A/MYC/ENY2/ACTB/PARK7/SIAH2/PSMD5/JOSD1/PSMA5/TFPT/OTUD4/USP42/PSMA2/USP5/ASXL2/EP300/PSME4/ASXL1/VCP/BAP1/SKP2/FOXK2/PSMB3/DDX58/USP16/YOD1/USP54/PSMD2	44
BP	GO:0046835	carbohydrate phosphorylation	9/1616	24/18670	0.0001049	0.02254	0.0209	NAGK/HK1/XYLB/FGGY/GALK2/PFKFB3/GALK1/HK2/PFKFB4	9
BP	GO:0009408	response to heat	31/1616	176/18670	0.0001072	0.02254	0.0209	PDCD6/NUP50/POLR2D/CAMK2D/CREBBP/THBS1/TRPV2/CLPB/FKBP4/IER5/NUP133/AAAS/HSPA1A/AKT1S1/NUP35/NOS3/RPA2/HDAC2/DNAJB1/MICA/EP300/MICB/SLU7/VCP/DNAJA1/HSPA1L/HSPA13/RPA1/DAXX/CDKN1A/SIRT1	31
BP	GO:0034605	cellular response to heat	26/1616	137/18670	0.0001077	0.02254	0.0209	PDCD6/NUP50/POLR2D/CAMK2D/CREBBP/THBS1/CLPB/FKBP4/IER5/NUP133/AAAS/HSPA1A/AKT1S1/NUP35/RPA2/HDAC2/DNAJB1/EP300/SLU7/VCP/HSPA1L/HSPA13/RPA1/DAXX/CDKN1A/SIRT1	26
BP	GO:0071383	cellular response to steroid hormone stimulus	40/1616	250/18670	0.0001089	0.02254	0.0209	PER1/EGLN2/CRY2/PHB/CARM1/NR4A2/NR1D2/CASP9/NR3C2/PAGR1/FKBP4/RHOXF1/RORA/RBM14/RXRB/KLF9/PARK7/CREBRF/BMP4/PRMT2/ZFP36L1/GPAM/DDX54/THRA/ZFP36L2/EP300/PAQR7/RNF4/NR1D1/SAFB2/DNAJA1/SKP2/NR3C1/ASS1/TP63/UBE3A/PMEPA1/DAXX/UFM1/SIRT1	40
BP	GO:0090559	regulation of membrane permeability	19/1616	86/18670	0.0001131	0.02259	0.02095	MOAP1/RASIP1/NMT1/HIP1R/CNP/MUL1/GSK3A/PDCD6IP/HSPA1A/BID/BNIP3/BCL2L1/DYNLT1/YWHAZ/HK2/TFDP2/MTRNR2L5/TP63/RHOT2	19
BP	GO:0009266	response to temperature stimulus	39/1616	243/18670	0.0001234	0.02335	0.02166	PDCD6/NUP50/NFKBIA/POLR2D/CAMK2D/CXCR4/CREBBP/THBS1/TRPV2/CLPB/FKBP4/IER5/NUP133/AAAS/HSPA1A/AKT1S1/NUP35/NOS3/RPA2/HDAC2/DNAJB1/RBM3/THRA/METRNL/MICA/EP300/MICB/SLU7/ADRB1/UCP2/VCP/DNAJA1/HSPA1L/EIF2AK4/HSPA13/RPA1/DAXX/CDKN1A/SIRT1	39
BP	GO:0009755	hormone-mediated signaling pathway	38/1616	235/18670	0.0001277	0.02335	0.02166	PER1/EGLN2/CRY2/PHB/CARM1/NR4A2/ADIPOR2/NR1D2/NR3C2/PAGR1/FKBP4/RHOXF1/RORA/RBM14/RXRB/PARK7/CREBRF/BMP4/PRMT2/GPAM/DDX54/THRA/EP300/PAQR7/RNF4/NR1D1/TSHR/SAFB2/DNAJA1/SKP2/LATS2/NR3C1/TP63/UBE3A/PMEPA1/DAXX/UFM1/SIRT1	38
BP	GO:0050688	regulation of defense response to virus	17/1616	73/18670	0.000129	0.02335	0.02166	PPM1B/ZC3H12A/PYCARD/IFIT1/TNFAIP3/ANKRD17/MUL1/DTX3L/ZCCHC3/RNF26/GPATCH3/RNF125/MICB/PQBP1/EIF2AK4/DDX58/TSPAN32	17
BP	GO:0030518	intracellular steroid hormone receptor signaling pathway	25/1616	132/18670	0.0001498	0.02495	0.02314	PER1/EGLN2/CRY2/PHB/CARM1/PAGR1/FKBP4/RHOXF1/RBM14/PARK7/PRMT2/GPAM/DDX54/EP300/RNF4/SAFB2/DNAJA1/SKP2/NR3C1/TP63/UBE3A/PMEPA1/DAXX/UFM1/SIRT1	25
BP	GO:0060337	type I interferon signaling pathway	20/1616	95/18670	0.0001529	0.02495	0.02314	IRF7/PTPN6/IFITM2/IRF2/ISG15/IFIT1/RSAD2/MUL1/OAS2/FADD/BST2/IFITM1/IFITM3/HLA-H/YTHDF3/HLA-A/IFNA10/HLA-C/OAS1/ISG20	20
BP	GO:0071357	cellular response to type I interferon	20/1616	95/18670	0.0001529	0.02495	0.02314	IRF7/PTPN6/IFITM2/IRF2/ISG15/IFIT1/RSAD2/MUL1/OAS2/FADD/BST2/IFITM1/IFITM3/HLA-H/YTHDF3/HLA-A/IFNA10/HLA-C/OAS1/ISG20	20
BP	GO:0000154	rRNA modification	11/1616	36/18670	0.0001551	0.02495	0.02314	NOP10/RPUSD2/FDXACB1/TRMT112/TFB1M/THUMPD1/NSUN4/NSUN5P2/METTL16/RRNAD1/TFB2M	11
BP	GO:0045010	actin nucleation	13/1616	49/18670	0.0001976	0.03009	0.02791	JMY/HIP1R/WHAMMP3/WHAMM/ARPC1B/GMFB/SPIRE2/CORO1B/CORO1A/WASL/FMN1/NCKAP1/ARPC5	13
BP	GO:0010821	regulation of mitochondrion organization	31/1616	182/18670	0.000201	0.03009	0.02791	RAC2/MOAP1/PRELID1/PYCARD/NMT1/PDCD5/HIP1R/MUL1/SH3GLB1/HAX1/GSK3A/TNFSF10/PARK7/GBA/HSPA1A/BID/SMURF1/BNIP3/BCL2L1/YWHAZ/HK2/GPX1/FNIP1/DHODH/TFDP2/BAP1/HSPA1L/TP63/RHOT2/HTT/ATP13A2	31
BP	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	35/1616	215/18670	0.0002026	0.03009	0.02791	PDCD6/DAP/EGLN3/TNFRSF10B/PYCARD/PDCD5/HIP1R/THBS1/MUL1/CASP9/RPS6KA1/PRDX3/PRDX5/CASP10/MYC/CTSH/CD27/TNFSF10/PARK7/SIAH2/BCL10/FADD/BID/KLF4/CDKN2D/LGALS9/HERPUD1/GPX1/FNIP1/VCP/TP63/ADORA2A/RAF1/SIRT1/IFT57	35
BP	GO:0046902	regulation of mitochondrial membrane permeability	17/1616	76/18670	0.0002175	0.0315	0.02922	MOAP1/NMT1/HIP1R/CNP/MUL1/GSK3A/HSPA1A/BID/BNIP3/BCL2L1/DYNLT1/YWHAZ/HK2/TFDP2/MTRNR2L5/TP63/RHOT2	17
BP	GO:0034340	response to type I interferon	20/1616	99/18670	0.0002743	0.03875	0.03594	IRF7/PTPN6/IFITM2/IRF2/ISG15/IFIT1/RSAD2/MUL1/OAS2/FADD/BST2/IFITM1/IFITM3/HLA-H/YTHDF3/HLA-A/IFNA10/HLA-C/OAS1/ISG20	20
BP	GO:0016072	rRNA metabolic process	39/1616	253/18670	0.0002902	0.03954	0.03667	CD3EAP/NOP10/GTF3A/GTF2H5/WDR46/RPUSD2/BYSL/SMARCB1/ABT1/FDXACB1/TRMT112/PA2G4/TFB1M/THUMPD1/BRF1/NSUN4/NSUN5P2/WDR75/METTL16/EXOSC5/RRNAD1/TBL3/DIS3/NOL9/DDX54/TFB2M/GTF3C4/KRR1/FAM207A/DDX24/UTP15/MRTO4/RPP40/DDX11/SBDS/ISG20/UTP23/SIRT1/C1D	39
BP	GO:0008380	RNA splicing	63/1616	469/18670	0.0003059	0.03954	0.03667	HNRNPA1L2/AAR2/MBNL2/CLP1/PTBP1/USP4/RBM25/WTAP/TSEN15/SNRPA1/POLR2D/SNIP1/DHX16/ZNF830/PTBP2/SFPQ/CIR1/PIK3R1/SF3A1/C2orf49/POLR2H/PRKRIP1/AKAP17A/METTL16/CLK4/CHERP/HSPA1A/FAM98B/RBM19/SCAF8/ELAVL1/RBM4B/SRRT/ESRP2/SNRNP25/TRPT1/RBM4/ZC3H10/SF3A2/SRSF11/SMN2/RBM38/RBM3/TGS1/RP9/HNRNPUL1/PPIL1/SLU7/PQBP1/AKAP8L/CWF19L1/SRRM1/PHF5A/SRSF10/HNRNPL/XAB2/HNRNPA1/WDR33/KHDRBS3/GEMIN7/RBM17/HNRNPH3/GPATCH1	63
BP	GO:0007050	cell cycle arrest	37/1616	237/18670	0.0003185	0.03954	0.03667	CDK4/SDE2/PRMT1/NOTCH1/CDK5/CARM1/CHEK2/JMY/PRKAB1/STRADB/WHAMMP3/THBS1/DUSP1/WHAMM/PRKAG2/VASH1/TCF7L2/MYC/CDKN2B/CDKN1B/TBRG4/BTG2/CDKN2D/WDR6/IL12A/GADD45A/TSG101/GATA6/EP300/SLC38A9/WNT10B/TFDP2/PPM1A/CNOT6L/EIF2AK4/CDKN1A/LAMTOR2	37
BP	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	37/1616	237/18670	0.0003185	0.03954	0.03667	PER1/PELI2/PIM2/IKBKB/PPM1B/TNFRSF10B/TERF2IP/ZC3H12A/PYCARD/TRAF6/MIER1/TNFAIP3/ANKRD17/MUL1/SHISA5/MAP3K7/GOLT1B/REL/MAP3K3/MAP3K14/NDFIP2/RORA/CASP10/TNFSF10/BCL10/FADD/ASH1L/RBCK1/BST2/CCDC22/LGALS9/PRKCE/NR1D1/BRD4/PPM1A/CTH/SIRT1	37
BP	GO:0000963	mitochondrial RNA processing	7/1616	17/18670	0.0003208	0.03954	0.03667	SUPV3L1/TBRG4/FASTKD5/TRMT10C/PUS1/TRMT5/CDK5RAP1	7
BP	GO:0001522	pseudouridine synthesis	7/1616	17/18670	0.0003208	0.03954	0.03667	NOP10/RPUSD2/PUSL1/RPUSD3/PUS1/TRUB1/PUS3	7
BP	GO:0048872	homeostasis of number of cells	38/1616	246/18670	0.0003306	0.03989	0.037	PRMT1/SIT1/NOTCH1/SRF/ERCC2/WDR48/UBAP2L/LAT/ISG15/TNFAIP3/POLB/IREB2/L3MBTL3/RASSF2/BCL10/ACVR1B/FADD/BMP4/HSPA1A/NOS3/NAPEPLD/SLC25A38/ZFP36L1/FANCC/SH2B3/TSC22D3/SOS1/LGALS9/THRA/ZNF16/RRN3/CORO1A/ASXL1/RC3H2/JAK3/BAP1/BCL6/SLC11A2	38
BP	GO:0006839	mitochondrial transport	39/1616	256/18670	0.0003699	0.04293	0.03981	CPT1B/RAC2/MOAP1/GRPEL1/SLC25A30/NMT1/PDCD5/MRS2/HIP1R/CHCHD4/CNP/MUL1/TOMM20L/SLC25A6/SH3GLB1/PRKAG2/HAX1/GSK3A/SLC25A20/SLC25A28/SLC25A36/HSPA1A/BID/TIMM13/BNIP3/SLC25A38/BCL2L1/DYNLT1/YWHAZ/HK2/UCP2/TIMM10/TFDP2/BAP1/HSPA1L/MTRNR2L5/TP63/RHOT2/MPC1	39
BP	GO:0008637	apoptotic mitochondrial changes	23/1616	124/18670	0.0003705	0.04293	0.03981	PIM2/MOAP1/PRELID1/PYCARD/NMT1/PDCD5/HIP1R/MUL1/ATP2A1/GSK3A/TNFSF10/SLC25A4/HSPA1A/BID/BNIP3/BCL2L1/YWHAZ/HK2/GPX1/TFDP2/MTRNR2L5/TP63/RHOT2	23
BP	GO:1903320	regulation of protein modification by small protein conjugation or removal	36/1616	231/18670	0.0003942	0.04478	0.04153	PDCD6/PARP10/CDK5/FEM1B/PHF23/USP4/WDR48/ISG15/ZC3H12A/TOPORS/TRAF6/TNFAIP3/MUL1/DTX3L/TRIB3/SPRTN/NDFIP2/GSK3A/PARK7/SIAH2/BCL10/HSPA1A/MASTL/GORASP1/SPOPL/OTUD4/SENP2/ARRDC4/GLMN/PRKCE/HERPUD1/VCP/DNAJA1/SKP2/UBE3A/DAXX	36
BP	GO:0010822	positive regulation of mitochondrion organization	22/1616	117/18670	0.0004042	0.04503	0.04176	RAC2/MOAP1/PYCARD/NMT1/PDCD5/HIP1R/MUL1/SH3GLB1/GSK3A/TNFSF10/PARK7/GBA/BID/SMURF1/BNIP3/YWHAZ/HK2/TFDP2/BAP1/HSPA1L/TP63/HTT	22
BP	GO:0006283	transcription-coupled nucleotide-excision repair	16/1616	73/18670	0.0004212	0.04573	0.04241	POLD2/GTF2H5/ERCC2/POLR2D/COPS7A/POLD4/ZNF830/XRCC1/POLR2H/MNAT1/RPA2/DDB1/GTF2H4/EP300/XAB2/RPA1	16
BP	GO:0031647	regulation of protein stability	42/1616	284/18670	0.0004263	0.04573	0.04241	PIM1/CCT5/AAK1/PIM2/ISOC2/PHB/USP4/GET4/CHEK2/PYCARD/HIP1R/CREBBP/MUL1/PEX6/CCT6A/SH3GLB1/PIK3R1/GRN/PDCD10/CTSH/CTSA/PARK7/RASSF2/HSPA1A/WDR81/FKBPL/ATP1B2/SENP2/FBXL3/CDKN2AIP/IRGM/EP300/PER3/NR1D1/WNT10B/TSC1/KDM8/CCDC88C/HTT/APOA1/CDKN1A/SIRT1	42
BP	GO:0001510	RNA methylation	17/1616	81/18670	0.0004833	0.05049	0.04682	WTAP/PCIF1/FDXACB1/TRMT112/TFB1M/NSUN4/NSUN5P2/METTL16/TRMT10C/RRNAD1/TRMT5/TRMT13/TFB2M/TGS1/ALKBH8/NSUN2/THUMPD2	17
BP	GO:0007623	circadian rhythm	33/1616	208/18670	0.0004881	0.05049	0.04682	PER1/CDK4/CRY2/JUND/AHCY/SIK1/KDM2A/NR1D2/SFPQ/RORA/KLF9/SIAH2/CSNK1E/BTBD9/CSNK1D/RBM4B/HDAC2/OPN3/DDB1/RBM4/SRRD/FBXL3/EP300/PER3/NR1D1/ATF4/ASS1/UBE3A/ADORA2A/KDM8/PHLPP1/NCOA2/SIRT1	33
BP	GO:0048545	response to steroid hormone	53/1616	385/18670	0.0004972	0.05053	0.04686	PER1/EGLN2/CRY2/PHB/NOTCH1/CARM1/NR4A2/NR1D2/THBS1/CASP9/DUSP1/NR3C2/PAGR1/FKBP4/RHOXF1/RORA/RBM14/RXRB/KLF9/PARK7/CREBRF/BMP4/GBA/PRMT2/CATSPER2/ZFP36L1/GPAM/DDX54/THRA/ADAM9/ZFP36L2/EP300/PAQR7/RNF4/NR1D1/GNRH1/SAFB2/COL1A1/DNAJA1/CAD/SKP2/NR3C1/ASS1/TP63/UBE3A/PMEPA1/DAXX/NCOA2/UFM1/ALAD/CDKN1A/SIRT1/TGFBR2	53
BP	GO:0045747	positive regulation of Notch signaling pathway	13/1616	54/18670	0.0005547	0.0554	0.05138	AAK1/NOTCH1/TSPAN14/CREBBP/ASCL1/PDCD10/POGLUT1/NOS3/EP300/TSPAN5/MFNG/TP63/PRKCI	13
BP	GO:0000380	alternative mRNA splicing, via spliceosome	16/1616	76/18670	0.0006759	0.06511	0.06038	MBNL2/PTBP1/RBM25/WTAP/SFPQ/RBM19/RBM4B/ESRP2/RBM4/ZC3H10/SLU7/PQBP1/SRSF10/HNRNPL/HNRNPA1/RBM17	16
BP	GO:0032922	circadian regulation of gene expression	14/1616	62/18670	0.0006905	0.06511	0.06038	PER1/CRY2/KDM2A/RORA/CSNK1E/CSNK1D/RBM4B/HDAC2/PER3/NR1D1/ATF4/KDM8/NCOA2/SIRT1	14
BP	GO:0043414	macromolecule methylation	44/1616	309/18670	0.0007134	0.06511	0.06038	PRMT1/EHMT2/PHF1/CARM1/WTAP/SMARCB1/MEN1/PCIF1/FDXACB1/TRMT112/TFB1M/PIK3CA/PRDM4/PAGR1/NSUN4/NSUN5P2/MYC/METTL16/TRMT10C/PRMT2/NTMT1/BTG2/ASH1L/FAM98B/RRNAD1/TRMT5/TRMT13/TFB2M/ZNF274/JARID2/TGS1/MBD1/BRD4/MECP2/SETD1B/BAZ2A/WDR61/ALKBH8/TET1/NSUN2/THUMPD2/GFI1/MAPT-AS1/SIRT1	44
BP	GO:0034314	Arp2/3 complex-mediated actin nucleation	10/1616	36/18670	0.0007176	0.06511	0.06038	JMY/HIP1R/WHAMMP3/WHAMM/ARPC1B/GMFB/CORO1B/WASL/NCKAP1/ARPC5	10
BP	GO:0042752	regulation of circadian rhythm	21/1616	114/18670	0.0007178	0.06511	0.06038	PER1/CRY2/SIK1/KDM2A/NR1D2/SFPQ/RORA/SIAH2/CSNK1E/CSNK1D/RBM4B/OPN3/DDB1/RBM4/SRRD/FBXL3/PER3/NR1D1/UBE3A/ADORA2A/PHLPP1	21
BP	GO:0031396	regulation of protein ubiquitination	32/1616	204/18670	0.0007193	0.06511	0.06038	PDCD6/PARP10/CDK5/FEM1B/PHF23/USP4/WDR48/ISG15/TOPORS/TRAF6/TNFAIP3/DTX3L/TRIB3/SPRTN/NDFIP2/GSK3A/PARK7/SIAH2/BCL10/HSPA1A/MASTL/GORASP1/SPOPL/SENP2/ARRDC4/GLMN/PRKCE/HERPUD1/DNAJA1/SKP2/UBE3A/DAXX	32
BP	GO:0019058	viral life cycle	46/1616	328/18670	0.0007615	0.06787	0.06294	NUP50/SLC20A2/IFITM2/PARP10/TBC1D20/NOTCH1/HYAL3/SMARCB1/ISG15/ZC3H12A/CXCR4/IFIT1/SLC52A2/RSAD2/DDX6/VPS37B/SLC1A5/SIVA1/VPS18/ATG16L1/NUP133/CDHR3/PDCD6IP/PKN2/AAAS/HSPA1A/NUP35/TRIM11/DYNLT1/BST2/DDB1/AICDA/IFITM1/TSG101/IFITM3/LGALS9/CD46/VCP/EIF2AK4/RAB1B/OAS1/SELPLG/ISG20/NFIA/HAVCR1/ZNF639	46
BP	GO:0006364	rRNA processing	33/1616	214/18670	0.0008125	0.07131	0.06614	NOP10/GTF2H5/WDR46/RPUSD2/BYSL/ABT1/FDXACB1/TRMT112/PA2G4/TFB1M/THUMPD1/NSUN4/NSUN5P2/WDR75/METTL16/EXOSC5/RRNAD1/TBL3/DIS3/NOL9/DDX54/TFB2M/KRR1/FAM207A/DDX24/UTP15/MRTO4/RPP40/SBDS/ISG20/UTP23/SIRT1/C1D	33
BP	GO:0032259	methylation	50/1616	366/18670	0.0008393	0.07153	0.06634	PRMT1/EHMT2/PHF1/CARM1/WTAP/MAT2B/SMARCB1/AHCY/METTL23/MEN1/PCIF1/FDXACB1/TRMT112/TFB1M/PIK3CA/PRDM4/PAGR1/NSUN4/SMYD5/NSUN5P2/MYC/METTL16/TRMT10C/PRMT2/NTMT1/BTG2/ASH1L/FAM98B/RRNAD1/TRMT5/INMT/TRMT13/TFB2M/ZNF274/JARID2/TGS1/MAT2A/MBD1/BRD4/MECP2/SETD1B/BAZ2A/WDR61/ALKBH8/TET1/NSUN2/THUMPD2/GFI1/MAPT-AS1/SIRT1	50
BP	GO:0009396	folic acid-containing compound biosynthetic process	5/1616	10/18670	0.0008396	0.07153	0.06634	GART/MTHFS/GCH1/DHFR/MTHFD1L	5
BP	GO:0007249	I-kappaB kinase/NF-kappaB signaling	39/1616	269/18670	0.0009866	0.08174	0.07581	PER1/PELI2/PIM2/NFKBIA/IKBKB/PPM1B/TNFRSF10B/TERF2IP/ZC3H12A/PYCARD/SNIP1/TRAF6/MIER1/TNFAIP3/ANKRD17/MUL1/SHISA5/MAP3K7/GOLT1B/REL/MAP3K3/MAP3K14/NDFIP2/RORA/CASP10/TNFSF10/BCL10/FADD/ASH1L/RBCK1/BST2/CCDC22/LGALS9/PRKCE/NR1D1/BRD4/PPM1A/CTH/SIRT1	39
BP	GO:0050792	regulation of viral process	32/1616	208/18670	0.001006	0.08174	0.07581	CCNT1/IFITM2/PARP10/TBC1D20/NOTCH1/TAF11/SMARCB1/POLR2D/ISG15/ZC3H12A/CXCR4/IFIT1/RSAD2/VPS37B/POLR2H/PKN2/TRIM11/DYNLT1/BST2/DDB1/AICDA/IFITM1/TSG101/IFITM3/LGALS9/RSF1/CFL1/EP300/EIF2AK4/OAS1/ISG20/ZNF639	32
BP	GO:1903599	positive regulation of autophagy of mitochondrion	7/1616	20/18670	0.001014	0.08174	0.07581	MUL1/PARK7/GBA/SMURF1/BNIP3/HK2/HTT	7
BP	GO:0018158	protein oxidation	6/1616	15/18670	0.00105	0.08174	0.07581	CHCHD4/LOXL2/PRDX3/PARK7/GPX1/APOA1	6
BP	GO:1900034	regulation of cellular response to heat	16/1616	79/18670	0.001052	0.08174	0.07581	NUP50/CAMK2D/CREBBP/FKBP4/IER5/NUP133/AAAS/HSPA1A/AKT1S1/NUP35/RPA2/DNAJB1/EP300/HSPA1L/RPA1/SIRT1	16
BP	GO:1903311	regulation of mRNA metabolic process	45/1616	324/18670	0.001058	0.08174	0.07581	CCNT1/MBNL2/PTBP1/DCP1A/RBM25/WTAP/ZC3H12A/SERBP1/PSME2/TNRC6B/METTL16/TBRG4/HSPA1A/EXOSC5/BTG2/RBM19/ELAVL1/RBM4B/DHX34/DIS3/PSMD5/ZFP36L1/RBM4/ZC3H10/PSMA5/DCP2/RBM38/RBM3/FTO/PSMA2/YWHAZ/GTPBP1/ZFP36L2/PSME4/YTHDF3/SRSF10/SAFB2/HNRNPL/HNRNPA1/CNOT6L/UPF1/KHDRBS3/PSMB3/RBM17/PSMD2	45
BP	GO:0038061	NIK/NF-kappaB signaling	29/1616	183/18670	0.001058	0.08174	0.07581	NFKBIA/PPM1B/TNFRSF10B/TERF2IP/ZC3H12A/TRAF6/MAP3K7/REL/NR3C2/MAP3K14/PSME2/CD27/RASSF2/C1QTNF3/DICER1/NFKB2/PSMD5/RBCK1/PSMA5/LGALS9/PSMA2/EP300/PSME4/ZFP91/RC3H2/PPM1A/PSMB3/PSMD2/TRAF4	29
BP	GO:0051125	regulation of actin nucleation	8/1616	26/18670	0.00117	0.08919	0.08272	HIP1R/WHAMM/GMFB/CORO1B/CORO1A/WASL/FMN1/NCKAP1	8
BP	GO:0045862	positive regulation of proteolysis	49/1616	363/18670	0.001221	0.09183	0.08516	PDCD6/PHB/DAP/EGLN3/WDR48/TNFRSF10B/PRELID1/ZC3H12A/PYCARD/PDCD5/SOCS4/HIP1R/NFE2L2/MUL1/CASP9/TRIB3/GRN/PSME2/ZFAND2A/CASP10/MYC/CTSH/GSK3A/TNFSF10/FBXO22/BCL10/CSNK1E/FADD/GBA/HSPA1A/BID/CSNK1D/SMURF1/HDAC2/MMP14/TMTC3/CEBPA/CCDC22/LGALS9/ADAM9/USP5/HERPUD1/PSME4/AKIRIN2/VCP/SOCS5/KCNE2/SIRT1/IFT57	49
BP	GO:0043484	regulation of RNA splicing	23/1616	135/18670	0.001259	0.09321	0.08645	MBNL2/PTBP1/RBM25/WTAP/PTBP2/PIK3R1/AKAP17A/METTL16/CLK4/HSPA1A/RBM19/RBM4B/ESRP2/RBM4/ZC3H10/RBM38/RBM3/PQBP1/SRSF10/HNRNPL/HNRNPA1/KHDRBS3/RBM17	23
BP	GO:0001933	negative regulation of protein phosphorylation	56/1616	429/18670	0.001271	0.09321	0.08645	PER1/SNX25/PTPN6/GBP1/PHB/DUSP8/RGS14/TERF2IP/ZC3H12A/MVP/PYCARD/MEN1/RASIP1/CSK/SOCS4/SOCS3/TNFAIP3/DUSP1/TRIB3/CEACAM1/PRKAG2/PRKRIP1/MYC/PPP1R15B/GMFB/PARK7/RASSF2/CDKN2B/CDKN1B/MBIP/SMCR8/BMP4/GBA/TWIST1/AKT1S1/ASH1L/KLF4/CDKN2D/ATG14/SH2B3/CEBPA/GADD45A/TSG101/CBLB/DBNDD2/PPEF2/DNAJA1/LATS2/ZGPAT/ADORA2A/PMEPA1/DUSP7/SOCS5/CDKN1A/CDK5RAP1/SIRT1	56
BP	GO:0010498	proteasomal protein catabolic process	61/1616	477/18670	0.001318	0.09456	0.0877	RNF103/GET4/TOPORS/SOCS4/SCO1/NFE2L2/HM13/FBXW4/TRIB3/TLK2/PSME2/ZFAND2A/BFAR/GSK3A/ENC1/PARK7/FBXO22/SIAH2/CSNK1E/ANAPC7/GBA/HSPA1A/CSNK1D/DNAJB9/SMURF1/PSMD5/RBCK1/FBXO33/DDB1/TMTC3/PSMA5/KIF14/SGTB/CEBPA/ZNRF1/SPOPL/GLMN/PSMA2/USP5/FBXL3/HERPUD1/RMND5B/RNF4/NR1D1/TRIM2/PSME4/GPX1/WNT10B/VCP/SPOP/SKP2/MAP1A/PSMB3/UBE3A/HSPA13/YOD1/SOCS5/ALAD/KCNE2/PSMD2/SIRT1	61
BP	GO:0045071	negative regulation of viral genome replication	13/1616	59/18670	0.001349	0.09456	0.0877	IFITM2/PARP10/ISG15/ZC3H12A/IFIT1/RSAD2/BST2/AICDA/IFITM1/IFITM3/EIF2AK4/OAS1/ISG20	13
BP	GO:1990823	response to leukemia inhibitory factor	18/1616	96/18670	0.001355	0.09456	0.0877	PIGA/SOCS3/PDCD10/GFPT2/EIF4A2/NUP35/KLF4/MRPL15/RFX2/JARID2/MAT2A/HK2/MYNN/BCLAF1/CTH/PFKP/MPC1/SIRT1	18
BP	GO:1990830	cellular response to leukemia inhibitory factor	18/1616	96/18670	0.001355	0.09456	0.0877	PIGA/SOCS3/PDCD10/GFPT2/EIF4A2/NUP35/KLF4/MRPL15/RFX2/JARID2/MAT2A/HK2/MYNN/BCLAF1/CTH/PFKP/MPC1/SIRT1	18
BP	GO:0043153	entrainment of circadian clock by photoperiod	7/1616	21/18670	0.001409	0.09631	0.08932	PER1/CRY2/SIK1/RBM4B/RBM4/FBXL3/PER3	7
BP	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	10/1616	39/18670	0.001413	0.09631	0.08932	TNFRSF10B/TNFAIP3/TNFSF10/PARK7/FADD/NOS3/BCL2L1/FAIM2/GPX1/RAF1	10
BP	GO:2000116	regulation of cysteine-type endopeptidase activity	35/1616	239/18670	0.001463	0.09854	0.09139	PDCD6/DAP/EGLN3/TNFRSF10B/PYCARD/PDCD5/HIP1R/THBS1/MUL1/CASP9/RPS6KA1/PRDX3/PRDX5/CASP10/MYC/CTSH/CD27/TNFSF10/PARK7/SIAH2/BCL10/FADD/BID/KLF4/CDKN2D/LGALS9/HERPUD1/GPX1/FNIP1/VCP/TP63/ADORA2A/RAF1/SIRT1/IFT57	35
BP	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	9/1616	33/18670	0.001517	0.09973	0.09249	MEN1/TNFAIP3/CDKN2B/CDKN1B/CDKN2D/CEBPA/LATS2/CDKN1A/CDK5RAP1	9
BP	GO:0009649	entrainment of circadian clock	8/1616	27/18670	0.001538	0.09973	0.09249	PER1/CRY2/SIK1/RBM4B/RBM4/FBXL3/PER3/PHLPP1	8
BP	GO:0031167	rRNA methylation	8/1616	27/18670	0.001538	0.09973	0.09249	FDXACB1/TRMT112/TFB1M/NSUN4/NSUN5P2/METTL16/RRNAD1/TFB2M	8
BP	GO:2001235	positive regulation of apoptotic signaling pathway	28/1616	179/18670	0.001562	0.09973	0.09249	SERINC3/MOAP1/PYCARD/NMT1/PDCD5/HIP1R/THBS1/SFPQ/CTSH/GSK3A/ING5/TNFSF10/PARK7/BCL10/FADD/BID/PLAGL2/BNIP3/BCL2L1/RBCK1/LGALS9/YWHAZ/TFDP2/TP63/ADORA2A/BCLAF1/TRIM39/SIRT1	28
BP	GO:0045185	maintenance of protein location	19/1616	105/18670	0.001567	0.09973	0.09249	MXI1/NFKBIE/HK1/NFKBIA/CDK5/GET4/TOPORS/INSIG1/SRI/PARK7/TWF2/CCDC22/G3BP2/TWF1/TMSB4Y/HK2/SPAG4/ANKRD13C/GPAA1	19
BP	GO:0070228	regulation of lymphocyte apoptotic process	12/1616	53/18670	0.001592	0.1003	0.09298	PRELID1/CD27/BCL10/FADD/BMP4/LGALS14/TSC22D3/LGALS9/IRS2/JAK3/FNIP1/BCL6	12
BP	GO:0048511	rhythmic process	41/1616	295/18670	0.001698	0.1058	0.09812	PER1/CDK4/CRY2/CDK5/JUND/AHCY/SIK1/KDM2A/ZNF830/NR1D2/CREBBP/SFPQ/RORA/KLF9/SIAH2/CSNK1E/NFKB2/TWIST1/BTBD9/CSNK1D/NOS3/RBM4B/HDAC2/OPN3/DDB1/RBM4/SRRD/FBXL3/EP300/PER3/NR1D1/ATF4/GNRH1/ASS1/UBE3A/ADORA2A/KDM8/PHLPP1/NCOA2/ENOX1/SIRT1	41
BP	GO:0016570	histone modification	58/1616	454/18670	0.001748	0.1072	0.09938	PER1/PRMT1/AKAP8/EHMT2/PHB/CDK5/PHF1/CARM1/ATXN7/SMARCB1/CAMK2D/MEN1/KDM2A/MIER1/CREBBP/SFPQ/MORF4L1/DTX3L/MAP3K7/PRDM4/PAGR1/ACTL6A/RBM14/ENY2/ING5/KAT7/MBIP/TWIST1/PRMT2/NTMT1/ASH1L/KANSL2/HDAC2/BRPF1/DDB1/RSF1/ZNF274/JARID2/GTF3C4/EP300/BRD4/AKAP8L/PHF20/MECP2/ASXL1/BRD1/SETD1B/BAZ2A/PHF2/WDR61/BAP1/TADA1/BCL6/TET1/KDM8/USP16/GFI1/SIRT1	58
BP	GO:0019079	viral genome replication	21/1616	122/18670	0.001757	0.1072	0.09938	IFITM2/PARP10/TBC1D20/NOTCH1/SMARCB1/ISG15/ZC3H12A/IFIT1/RSAD2/ATG16L1/PKN2/BST2/DDB1/AICDA/IFITM1/IFITM3/VCP/EIF2AK4/OAS1/ISG20/NFIA	21
BP	GO:0009416	response to light stimulus	43/1616	314/18670	0.00178	0.1074	0.0996	PER1/SDE2/CRY2/CDK5/ZBTB1/ERCC2/RGS14/HYAL3/JUND/MEN1/SIK1/NMT1/CREBBP/CASP9/DUSP1/DYNLRB1/PIK3R1/SPRTN/CACNA2D4/PDE6G/MYC/DNM2/SLC4A10/NLGN3/RBM4B/CDKN2D/OPN3/DDB1/RBM4/IL12A/MEIS2/FBXL3/EP300/PER3/ATF4/MECP2/RCVRN/GPX1/CTNS/MFAP4/EIF2AK4/CDKN1A/SIRT1	43
BP	GO:0016569	covalent chromatin modification	60/1616	474/18670	0.001831	0.1093	0.1014	PER1/PRMT1/AKAP8/EHMT2/PHB/CDK5/PHF1/CARM1/ATXN7/SMARCB1/CAMK2D/MEN1/KDM2A/MIER1/CREBBP/SFPQ/MORF4L1/DTX3L/MAP3K7/PRDM4/PAGR1/ACTL6A/RBM14/ENY2/ING5/KAT7/MBIP/TWIST1/PRMT2/NTMT1/ASH1L/KANSL2/HDAC2/BRPF1/DDB1/AICDA/RSF1/ZNF274/JARID2/GTF3C4/EP300/MBD1/BRD4/AKAP8L/PHF20/MECP2/ASXL1/BRD1/SETD1B/BAZ2A/PHF2/WDR61/BAP1/TADA1/BCL6/TET1/KDM8/USP16/GFI1/SIRT1	60
BP	GO:0097345	mitochondrial outer membrane permeabilization	12/1616	54/18670	0.001889	0.1108	0.1028	MOAP1/NMT1/HIP1R/MUL1/GSK3A/HSPA1A/BID/BNIP3/YWHAZ/TFDP2/TP63/RHOT2	12
BP	GO:1904030	negative regulation of cyclin-dependent protein kinase activity	9/1616	34/18670	0.001907	0.1108	0.1028	MEN1/TNFAIP3/CDKN2B/CDKN1B/CDKN2D/CEBPA/LATS2/CDKN1A/CDK5RAP1	9
BP	GO:0016556	mRNA modification	7/1616	22/18670	0.001913	0.1108	0.1028	WTAP/PCIF1/METTL16/TRMT10C/PUS1/TRUB1/PUS3	7
BP	GO:0030838	positive regulation of actin filament polymerization	18/1616	99/18670	0.001944	0.1114	0.1033	PYCARD/JMY/HIP1R/WHAMMP3/WHAMM/ARPC1B/GMFB/RICTOR/SPIRE2/VASP/CORO1B/PRKCE/CORO1A/FCHSD1/WASL/FMN1/NCKAP1/ARPC5	18
BP	GO:0009108	coenzyme biosynthetic process	37/1616	261/18670	0.001962	0.1114	0.1033	NUP50/GART/PARP10/HK1/PGAM4/MAT2B/MTHFS/RFK/PDHA1/PRKAG2/CBR4/GCH1/NUP133/COQ10B/DHFR/METTL16/ASPDH/AAAS/NUP35/PFKFB3/GALK1/PGK2/ACSL3/MAT2A/HK2/PFKL/COQ7/MTHFD1L/FOXK2/COQ9/PNPO/PPTC7/PFKFB4/PFKP/DLD/MPC1/ENTPD5	37
BP	GO:0036296	response to increased oxygen levels	8/1616	28/18670	0.001992	0.1119	0.1038	CDK4/POLB/BNIP3/HDAC2/TMEM199/ATP6V1G1/COL1A1/CDKN1A	8
BP	GO:0009166	nucleotide catabolic process	28/1616	182/18670	0.002009	0.1119	0.1038	NUP50/HK1/PGAM4/CNP/PRKAG2/NUDT9/NUP133/NUDT4/ASPDH/AAAS/NUP35/NUDT1/PDE7A/PFKFB3/DCTPP1/GALK1/PGK2/HK2/GPX1/PFKL/VCP/SMUG1/FOXK2/PNP/PFKFB4/PFKP/NT5C1A/ENTPD5	28
BP	GO:0006914	autophagy	62/1616	496/18670	0.002099	0.1147	0.1064	RGS19/PIM2/DAP/CDK5/NRBF2/PHF23/TM9SF1/ZC3H12A/PYCARD/RASIP1/PRKAB1/ZKSCAN3/MUL1/VPS37B/SH3GLB1/TRIB3/MAP3K7/PIK3CA/PRKAG2/VPS18/TLK2/ATG16L1/HAX1/GSK3A/CTSA/PARK7/EXOC8/TEX264/SMCR8/MTMR14/GBA/WDR81/EMC6/SMURF1/BNIP3/WDR6/ATG14/SNAPIN/TSG101/ATG2A/TRIM65/ATP6V1G1/IRGM/EP300/CTSK/HK2/WDR24/SLC38A9/ATP6V0E1/VCP/TSC1/EIF2AK4/FOXK2/DYNLL1/RAB1B/HTT/YOD1/SPTLC2/ATP13A2/LAMTOR2/SIRT1/SBF2	62
BP	GO:0061919	process utilizing autophagic mechanism	62/1616	496/18670	0.002099	0.1147	0.1064	RGS19/PIM2/DAP/CDK5/NRBF2/PHF23/TM9SF1/ZC3H12A/PYCARD/RASIP1/PRKAB1/ZKSCAN3/MUL1/VPS37B/SH3GLB1/TRIB3/MAP3K7/PIK3CA/PRKAG2/VPS18/TLK2/ATG16L1/HAX1/GSK3A/CTSA/PARK7/EXOC8/TEX264/SMCR8/MTMR14/GBA/WDR81/EMC6/SMURF1/BNIP3/WDR6/ATG14/SNAPIN/TSG101/ATG2A/TRIM65/ATP6V1G1/IRGM/EP300/CTSK/HK2/WDR24/SLC38A9/ATP6V0E1/VCP/TSC1/EIF2AK4/FOXK2/DYNLL1/RAB1B/HTT/YOD1/SPTLC2/ATP13A2/LAMTOR2/SIRT1/SBF2	62
BP	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	28/1616	183/18670	0.002181	0.1147	0.1064	PELI2/PIM2/IKBKB/TNFRSF10B/TERF2IP/TRAF6/MIER1/ANKRD17/MUL1/SHISA5/MAP3K7/GOLT1B/REL/MAP3K3/MAP3K14/NDFIP2/CASP10/TNFSF10/BCL10/FADD/RBCK1/BST2/CCDC22/LGALS9/PRKCE/BRD4/PPM1A/CTH	28
BP	GO:0042326	negative regulation of phosphorylation	59/1616	468/18670	0.002184	0.1147	0.1064	PER1/SNX25/PTPN6/GBP1/PHB/DUSP8/RGS14/TERF2IP/ZC3H12A/MVP/PYCARD/MEN1/RASIP1/CSK/SOCS4/SOCS3/TNFAIP3/DUSP1/TRIB3/CEACAM1/PRDX3/PRKAG2/PRKRIP1/MYC/PPP1R15B/GMFB/PARK7/RASSF2/CDKN2B/CDKN1B/MBIP/SMCR8/BMP4/GBA/TWIST1/AKT1S1/ASH1L/KLF4/CDKN2D/ATG14/SH2B3/CEBPA/GADD45A/TSG101/CBLB/DBNDD2/IRS2/PPEF2/DNAJA1/LATS2/ZGPAT/ADORA2A/DYNLL1/PMEPA1/DUSP7/SOCS5/CDKN1A/CDK5RAP1/SIRT1	59
BP	GO:2000058	regulation of ubiquitin-dependent protein catabolic process	24/1616	149/18670	0.002193	0.1147	0.1064	SOCS4/NFE2L2/TRIB3/TLK2/ZFAND2A/GSK3A/PARK7/FBXO22/CSNK1E/GBA/HSPA1A/CSNK1D/SMURF1/CEBPA/CCDC22/GLMN/USP5/HERPUD1/WNT10B/VCP/MAP1A/UBE3A/SOCS5/TRIM39	24
BP	GO:0061014	positive regulation of mRNA catabolic process	11/1616	48/18670	0.002222	0.1147	0.1064	ZC3H12A/TNRC6B/METTL16/BTG2/ZFP36L1/FTO/GTPBP1/ZFP36L2/YTHDF3/CNOT6L/UPF1	11
BP	GO:0035855	megakaryocyte development	6/1616	17/18670	0.002233	0.1147	0.1064	ABI1/PTPN6/SRF/FLI1/SH2B3/EP300	6
BP	GO:0042994	cytoplasmic sequestering of transcription factor	6/1616	17/18670	0.002233	0.1147	0.1064	MXI1/NFKBIE/NFKBIA/SRI/CCDC22/G3BP2	6
BP	GO:0070585	protein localization to mitochondrion	23/1616	141/18670	0.002268	0.1147	0.1064	RAC2/HK1/MOAP1/GRPEL1/MTCH2/NMT1/PDCD5/CHCHD4/TOMM20L/SLC25A6/SH3GLB1/HAX1/GSK3A/BID/TIMM13/YWHAZ/HK2/TIMM10/DNAJA1/TFDP2/BAP1/HSPA1L/TP63	23
BP	GO:0090085	regulation of protein deubiquitination	5/1616	12/18670	0.002277	0.1147	0.1064	WDR48/ZC3H12A/PARK7/OTUD4/VCP	5
BP	GO:2000121	regulation of removal of superoxide radicals	5/1616	12/18670	0.002277	0.1147	0.1064	NFE2L2/GCH1/PARK7/DHFR/FBLN5	5
BP	GO:0070482	response to oxygen levels	51/1616	394/18670	0.002437	0.1201	0.1114	EGLN2/ENDOG/CDK4/HIF1AN/HMOX2/NOTCH1/SRF/EGLN3/ERCC2/NR4A2/AHCY/CXCR4/NFE2L2/CREBBP/THBS1/POLB/LOXL2/XRCC1/PSME2/RORA/MYC/CDKN1B/TWIST1/BNIP3/HDAC2/PSMD5/ZFP36L1/MMP14/PSMA5/SLC2A1/PRKCE/PSMA2/TMEM199/GATA6/ATP6V1G1/EP300/HK2/ATF4/PSME4/MECP2/UCP2/COL1A1/TSC1/PSMB3/RAF1/ALAD/CDKN1A/PSMD2/SIRT1/TGFBR2/SLC11A2	51
BP	GO:0006289	nucleotide-excision repair	19/1616	109/18670	0.00245	0.1201	0.1114	POLD2/GTF2H5/POLL/ERCC2/POLR2D/COPS7A/POLD4/ZNF830/XRCC1/POLR2H/MNAT1/RPA2/FANCC/DDB1/GTF2H4/EP300/XAB2/RPA1/SIRT1	19
BP	GO:0005996	monosaccharide metabolic process	40/1616	292/18670	0.002503	0.1201	0.1114	BRAT1/HK1/SLC35A2/XYLB/PPP1R3D/SIK1/FGGY/PDHA1/MAN2C1/PIK3CA/TKTL1/GDPGP1/TALDO1/RORA/SORD/FUT4/GSK3A/C1QTNF3/GALK2/DDB1/SLC2A1/POFUT2/PFKFB3/PRKCE/GALK1/PGK2/EP300/GALT/HK2/NR1D1/ATF4/IRS2/PFKL/FOXK2/PFKFB4/PFKP/OAS1/NCOA2/PASK/SIRT1	40
BP	GO:0033014	tetrapyrrole biosynthetic process	8/1616	29/18670	0.002545	0.1201	0.1114	MMACHC/IREB2/SLC25A38/SRRD/RSAD1/IBA57/ALAD/SLC11A2	8
BP	GO:0070229	negative regulation of lymphocyte apoptotic process	8/1616	29/18670	0.002545	0.1201	0.1114	CD27/BCL10/FADD/BMP4/TSC22D3/IRS2/JAK3/BCL6	8
BP	GO:0007006	mitochondrial membrane organization	22/1616	134/18670	0.00257	0.1201	0.1114	MOAP1/NMT1/PDCD5/HIP1R/CNP/MUL1/TOMM20L/GSK3A/HSPA1A/BID/TIMM13/BNIP3/BCL2L1/DYNLT1/YWHAZ/HK2/TIMM10/TFDP2/MTRNR2L5/TP63/RHOT2/CHCHD3	22
BP	GO:0032273	positive regulation of protein polymerization	22/1616	134/18670	0.00257	0.1201	0.1114	PYCARD/JMY/HIP1R/WHAMMP3/WHAMM/ARPC1B/TPPP3/GMFB/RICTOR/CDKN1B/SPIRE2/HSPA1A/VASP/CORO1B/PRKCE/CORO1A/MECP2/FCHSD1/WASL/FMN1/NCKAP1/ARPC5	22
BP	GO:1903362	regulation of cellular protein catabolic process	35/1616	247/18670	0.002573	0.1201	0.1114	SOCS4/SCO1/TNFAIP3/NFE2L2/TRIB3/TLK2/WDR91/PSME2/ZFAND2A/GSK3A/PARK7/FBXO22/CSNK1E/GBA/HSPA1A/CSNK1D/SMURF1/TMTC3/CEBPA/CCDC22/GLMN/USP5/HERPUD1/MGAT3/GPX1/WNT10B/VCP/MAP1A/UBE3A/YOD1/SOCS5/TRIM39/ALAD/KCNE2/ATP13A2	35
BP	GO:1903146	regulation of autophagy of mitochondrion	10/1616	42/18670	0.002577	0.1201	0.1114	MUL1/HAX1/GSK3A/PARK7/GBA/SMURF1/BNIP3/HK2/HTT/ATP13A2	10
BP	GO:0098586	cellular response to virus	12/1616	56/18670	0.002617	0.1201	0.1114	IRF7/ZC3H12A/ANKRD17/MAPK11/BCL2L1/ZCCHC3/IL12A/GPATCH3/LGALS9/RNF125/IRGM/DDX58	12
BP	GO:0043900	regulation of multi-organism process	52/1616	405/18670	0.002641	0.1201	0.1114	CCNT1/IFITM2/PARP10/TBC1D20/NOTCH1/PPM1B/TAF11/HYAL3/SMARCB1/POLR2D/ISG15/ZC3H12A/PYCARD/CXCR4/IFIT1/TRAF6/TNFAIP3/RSAD2/ANKRD17/MUL1/VPS37B/DTX3L/GRN/PLCB1/POLR2H/ACVR1B/PKN2/TRIM11/HDAC2/DYNLT1/BST2/DDB1/ZCCHC3/RNF26/AICDA/IFITM1/TSG101/IFITM3/GPATCH3/LGALS9/RSF1/CFL1/RNF125/EP300/MICB/PQBP1/EIF2AK4/DDX58/TSPAN32/OAS1/ISG20/ZNF639	52
BP	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	11/1616	49/18670	0.002645	0.1201	0.1114	PER1/PPM1B/ZC3H12A/PYCARD/TNFAIP3/RORA/ASH1L/CCDC22/NR1D1/PPM1A/SIRT1	11
BP	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	16/1616	86/18670	0.002654	0.1201	0.1114	MOAP1/FEM1B/TNFRSF10B/TNFAIP3/THBS1/PIK3R1/TNFSF10/PARK7/FADD/BID/NOS3/BCL2L1/FAIM2/GPX1/RAF1/DAXX	16
BP	GO:0002683	negative regulation of immune system process	58/1616	463/18670	0.002731	0.1214	0.1126	PTPN6/GBP1/PRMT1/NOTCH1/NFKBIA/LRCH1/PPM1B/ZC3H12A/TNFAIP3/NFE2L2/THBS1/MUL1/DUSP1/PIK3R1/CEACAM1/GRN/MILR1/FSTL3/PLCB1/MYC/BCL10/FADD/BMP4/ELF1/BST2/ZFP36L1/RNF26/TSC22D3/OTUD4/GPATCH3/LGALS9/GLMN/TRAFD1/MEIS2/UBASH3A/RNF125/MICA/IL27RA/LILRB3/TNFAIP8L2/GPR171/MICB/NR1D1/RC3H2/DDT/YTHDF3/GNRH1/GPX1/JAK3/WDR61/WASL/ADORA2A/BCL6/TSPAN32/SOCS5/C5/TOB2/APOA1	58
BP	GO:0044839	cell cycle G2/M phase transition	37/1616	266/18670	0.002733	0.1214	0.1126	CDK4/AKAP8/FOXN3/CHEK2/ZNF830/CENPJ/PSME2/PLCB1/MNAT1/CDKN2B/ODF2/DNM2/CSNK1E/SFI1/CSNK1D/MASTL/PSMD5/PSMA5/KIF14/ATAD5/PSMA2/ABCB1/PSME4/BRD4/AKAP8L/MECP2/WNT10B/NDE1/SKP2/CDC25B/PSMB3/DYNLL1/GPR132/KDM8/HAUS2/CDKN1A/PSMD2	37
BP	GO:0044786	cell cycle DNA replication	14/1616	71/18670	0.002746	0.1214	0.1126	STAG2/POLD2/CHEK2/POLD4/ZNF830/DBF4/PRIM1/RPA2/AICDA/ATAD5/SENP2/UPF1/BCL6/RPA1	14
BP	GO:2001233	regulation of apoptotic signaling pathway	52/1616	406/18670	0.002781	0.122	0.1132	SERINC3/MOAP1/FEM1B/NR4A2/TNFRSF10B/PRELID1/PYCARD/NMT1/PDCD5/STRADB/HIP1R/TNFAIP3/NFE2L2/THBS1/MUL1/SFPQ/MNT/TCF7L2/CTSH/GSK3A/ING5/TNFSF10/PARK7/SIAH2/BCL10/FADD/BMP4/HSPA1A/BID/NOS3/PLAGL2/BNIP3/BCL2L1/RBCK1/CDKN2D/ATAD5/LGALS9/YWHAZ/HERPUD1/RRN3/FAIM2/GPX1/DNAJA1/TFDP2/TP63/ADORA2A/RAF1/BCLAF1/CTH/HTT/TRIM39/SIRT1	52
BP	GO:0043620	regulation of DNA-templated transcription in response to stress	21/1616	127/18670	0.00291	0.1236	0.1146	EGLN2/HIF1AN/NOTCH1/EGLN3/RGS14/NFE2L2/CREBBP/RPS6KA1/PSME2/HSPA1A/PSMD5/DNAJB1/PSMA5/PSMA2/EP300/ATF4/PSME4/PSMB3/BCLAF1/CHD6/PSMD2	21
BP	GO:0072331	signal transduction by p53 class mediator	37/1616	267/18670	0.002915	0.1236	0.1146	PRMT1/EHMT2/CDK5/CARM1/TAF11/BATF/CHEK2/PYCARD/JMY/TOPORS/PRKAB1/SHISA5/PRKAG2/ING5/CDKN1B/MAPK11/TWIST1/BTG2/RPA2/HDAC2/BRPF1/RMI2/GADD45A/ATAD5/RRN3/TAF15/EP300/PHF20/NUAK1/TFDP2/TAF13/CNOT6L/TP63/RPA1/CDKN1A/SIRT1/ATRIP	37
BP	GO:0006360	transcription by RNA polymerase I	13/1616	64/18670	0.002922	0.1236	0.1146	CD3EAP/GTF2H5/ERCC2/SMARCB1/POLR2H/MNAT1/WDR75/GTF2H4/RRN3/ATF4/UTP15/BAZ2A/DDX11	13
BP	GO:0006361	transcription initiation from RNA polymerase I promoter	9/1616	36/18670	0.002925	0.1236	0.1146	CD3EAP/GTF2H5/ERCC2/SMARCB1/POLR2H/MNAT1/GTF2H4/RRN3/BAZ2A	9
BP	GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism	32/1616	222/18670	0.002931	0.1236	0.1146	CCNT1/IFITM2/PARP10/TBC1D20/NOTCH1/TAF11/SMARCB1/POLR2D/ISG15/ZC3H12A/CXCR4/IFIT1/RSAD2/VPS37B/POLR2H/PKN2/TRIM11/DYNLT1/BST2/DDB1/AICDA/IFITM1/TSG101/IFITM3/LGALS9/RSF1/CFL1/EP300/EIF2AK4/OAS1/ISG20/ZNF639	32
BP	GO:0019318	hexose metabolic process	35/1616	249/18670	0.002943	0.1236	0.1146	BRAT1/HK1/SLC35A2/PPP1R3D/SIK1/PDHA1/MAN2C1/PIK3CA/TKTL1/GDPGP1/RORA/SORD/FUT4/GSK3A/C1QTNF3/GALK2/DDB1/POFUT2/PFKFB3/GALK1/PGK2/EP300/GALT/HK2/NR1D1/ATF4/IRS2/PFKL/FOXK2/PFKFB4/PFKP/OAS1/NCOA2/PASK/SIRT1	35
BP	GO:0045069	regulation of viral genome replication	17/1616	95/18670	0.003045	0.1255	0.1164	IFITM2/PARP10/TBC1D20/NOTCH1/ISG15/ZC3H12A/IFIT1/RSAD2/PKN2/BST2/DDB1/AICDA/IFITM1/IFITM3/EIF2AK4/OAS1/ISG20	17
BP	GO:2000060	positive regulation of ubiquitin-dependent protein catabolic process	17/1616	95/18670	0.003045	0.1255	0.1164	SOCS4/NFE2L2/TRIB3/ZFAND2A/GSK3A/FBXO22/CSNK1E/GBA/HSPA1A/CSNK1D/SMURF1/CEBPA/CCDC22/USP5/HERPUD1/VCP/SOCS5	17
BP	GO:0071897	DNA biosynthetic process	29/1616	196/18670	0.003055	0.1255	0.1164	CCT5/CHTF8/NOP10/PARP10/POLD2/PHB/ZBTB1/POLL/TERF2IP/ISG15/MEN1/POLD4/DUSP1/POLB/CCT6A/SPRTN/ACD/MYC/RPA2/KLF4/CDKN2D/DCP2/TNKS/TNKS2/VCP/HNRNPA1/RPA1/CDKN1A/SIRT1	29
BP	GO:0000959	mitochondrial RNA metabolic process	10/1616	43/18670	0.003102	0.1266	0.1174	SUPV3L1/TBRG4/FASTKD5/TRMT10C/PUS1/DARS2/TRMT5/TFB2M/WARS2/CDK5RAP1	10
BP	GO:1903050	regulation of proteolysis involved in cellular protein catabolic process	31/1616	214/18670	0.003126	0.1267	0.1175	SOCS4/SCO1/NFE2L2/TRIB3/TLK2/PSME2/ZFAND2A/GSK3A/PARK7/FBXO22/CSNK1E/GBA/HSPA1A/CSNK1D/SMURF1/TMTC3/CEBPA/CCDC22/GLMN/USP5/HERPUD1/GPX1/WNT10B/VCP/MAP1A/UBE3A/YOD1/SOCS5/TRIM39/ALAD/KCNE2	31
BP	GO:0008064	regulation of actin polymerization or depolymerization	27/1616	179/18670	0.003174	0.1277	0.1184	CFL2/PYCARD/JMY/HIP1R/WHAMMP3/WHAMM/ARPC1B/SWAP70/WDR1/HAX1/GMFB/RICTOR/SPIRE2/TWF2/VASP/CAPZB/CORO1B/CFL1/PRKCE/TWF1/TMSB4Y/CORO1A/FCHSD1/WASL/FMN1/NCKAP1/ARPC5	27
BP	GO:0061157	mRNA destabilization	8/1616	30/18670	0.003211	0.1277	0.1184	ZC3H12A/METTL16/ZFP36L1/FTO/ZFP36L2/YTHDF3/CNOT6L/UPF1	8
BP	GO:1901292	nucleoside phosphate catabolic process	28/1616	188/18670	0.003242	0.1277	0.1184	NUP50/HK1/PGAM4/CNP/PRKAG2/NUDT9/NUP133/NUDT4/ASPDH/AAAS/NUP35/NUDT1/PDE7A/PFKFB3/DCTPP1/GALK1/PGK2/HK2/GPX1/PFKL/VCP/SMUG1/FOXK2/PNP/PFKFB4/PFKP/NT5C1A/ENTPD5	28
BP	GO:0140053	mitochondrial gene expression	25/1616	162/18670	0.003252	0.1277	0.1184	MRPS5/MRPS18C/MRPS26/MTRF1L/COA3/MRPL51/SUPV3L1/NSUN4/TSFM/RPUSD3/TBRG4/FASTKD5/TRMT10C/MRPL54/PUS1/MRPL15/DARS2/MRPL44/TRMT5/TFB2M/ERAL1/WARS2/MRPS21/MRPL24/CDK5RAP1	25
BP	GO:0071901	negative regulation of protein serine/threonine kinase activity	23/1616	145/18670	0.003269	0.1277	0.1184	PTPN6/DUSP8/RGS14/PYCARD/MEN1/RASIP1/TNFAIP3/DUSP1/PRKAG2/CDKN2B/CDKN1B/MBIP/BMP4/GBA/CDKN2D/SH2B3/CEBPA/DNAJA1/LATS2/DUSP7/CDKN1A/CDK5RAP1/SIRT1	23
BP	GO:0051220	cytoplasmic sequestering of protein	7/1616	24/18670	0.003331	0.1277	0.1184	MXI1/NFKBIE/NFKBIA/GET4/SRI/CCDC22/G3BP2	7
BP	GO:0009314	response to radiation	56/1616	448/18670	0.003348	0.1277	0.1184	PER1/BRAT1/SDE2/XRRA1/CRY2/CDK5/GTF2H5/ZBTB1/ERCC2/RGS14/HYAL3/CHEK2/JUND/MEN1/SIK1/NMT1/CREBBP/CASP9/DUSP1/POLB/DYNLRB1/PIK3R1/SPRTN/TLK2/CACNA2D4/PDE6G/MYC/DNM2/SLC4A10/JUNB/NLGN3/FKBPL/RBM4B/BCL2L1/CDKN2D/OPN3/DDB1/RBM4/IL12A/GADD45A/INIP/MEIS2/FBXL3/EP300/PER3/ATF4/NHEJ1/MECP2/RCVRN/GPX1/CTNS/MFAP4/EIF2AK4/ALAD/CDKN1A/SIRT1	56
BP	GO:0097191	extrinsic apoptotic signaling pathway	32/1616	224/18670	0.003373	0.1277	0.1184	MOAP1/FEM1B/TNFRSF10B/PYCARD/STRADB/TNFAIP3/THBS1/CASP9/PIK3R1/SIVA1/TCF7L2/CD27/GSK3A/TNFSF10/PARK7/SIAH2/BCL10/ACVR1B/FADD/BMP4/HSPA1A/BID/NOS3/BCL2L1/RBCK1/IL12A/FAIM2/GPX1/RAF1/DAXX/HTT/KRT8	32
BP	GO:0009791	post-embryonic development	16/1616	88/18670	0.003375	0.1277	0.1184	ERCC2/NR4A2/CSRNP1/IREB2/MYO1E/STK36/SLC4A10/BMP4/ASH1L/PLAGL2/KLF4/IMPAD1/DHCR7/MYO7A/MECP2/RC3H2	16
BP	GO:0042254	ribosome biogenesis	40/1616	297/18670	0.003394	0.1277	0.1184	NOP10/RPL23A/GTF3A/GTF2H5/WDR46/RPUSD2/BYSL/ABT1/FDXACB1/TRMT112/PA2G4/TFB1M/THUMPD1/NSUN4/NSUN5P2/WDR75/METTL16/EXOSC5/RRNAD1/TBL3/DIS3/CEBPZ/NOL9/DDX54/TFB2M/BRIX1/KRR1/RRN3/ERAL1/FAM207A/DDX24/UTP15/MRTO4/RPP40/TSC1/SBDS/ISG20/UTP23/SIRT1/C1D	40
BP	GO:0072655	establishment of protein localization to mitochondrion	22/1616	137/18670	0.003401	0.1277	0.1184	RAC2/HK1/MOAP1/GRPEL1/NMT1/PDCD5/CHCHD4/TOMM20L/SLC25A6/SH3GLB1/HAX1/GSK3A/BID/TIMM13/YWHAZ/HK2/TIMM10/DNAJA1/TFDP2/BAP1/HSPA1L/TP63	22
BP	GO:0030832	regulation of actin filament length	27/1616	180/18670	0.003434	0.1277	0.1184	CFL2/PYCARD/JMY/HIP1R/WHAMMP3/WHAMM/ARPC1B/SWAP70/WDR1/HAX1/GMFB/RICTOR/SPIRE2/TWF2/VASP/CAPZB/CORO1B/CFL1/PRKCE/TWF1/TMSB4Y/CORO1A/FCHSD1/WASL/FMN1/NCKAP1/ARPC5	27
BP	GO:0034214	protein hexamerization	5/1616	13/18670	0.003439	0.1277	0.1184	LRRC8A/UGDH/MAT2A/YME1L1/VCP	5
BP	GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors	12/1616	58/18670	0.003559	0.131	0.1215	FEM1B/TNFRSF10B/TNFAIP3/THBS1/TNFSF10/PARK7/FADD/NOS3/BCL2L1/FAIM2/GPX1/RAF1	12
BP	GO:0050691	regulation of defense response to virus by host	9/1616	37/18670	0.003573	0.131	0.1215	ZC3H12A/PYCARD/TNFAIP3/MUL1/DTX3L/MICB/PQBP1/EIF2AK4/DDX58	9
BP	GO:0000731	DNA synthesis involved in DNA repair	11/1616	51/18670	0.003686	0.1339	0.1242	PARP10/POLD2/ZBTB1/ISG15/POLD4/SPRTN/RPA2/CDKN2D/VCP/RPA1/SIRT1	11
BP	GO:0070897	transcription preinitiation complex assembly	10/1616	44/18670	0.003709	0.1339	0.1242	TAF11/SMARCB1/BRF2/BRF1/TBPL1/THRA/MED6/RRN3/WNT10B/BAZ2A	10
BP	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	15/1616	81/18670	0.003722	0.1339	0.1242	SOCS4/NFE2L2/TRIB3/ZFAND2A/GSK3A/FBXO22/CSNK1E/GBA/HSPA1A/CSNK1D/CEBPA/USP5/HERPUD1/VCP/SOCS5	15
BP	GO:0008593	regulation of Notch signaling pathway	18/1616	105/18670	0.00378	0.1343	0.1245	AAK1/HIF1AN/NOTCH1/NFKBIA/TSPAN14/CREBBP/ASCL1/PDCD10/POGLUT1/NOS3/MMP14/CD46/EP300/TSPAN5/MFNG/TP63/BCL6/PRKCI	18
BP	GO:0014020	primary neural tube formation	17/1616	97/18670	0.003808	0.1343	0.1245	SEMA4C/FZD6/TRAF6/BCL10/BMP4/TWIST1/VASP/GLMN/CFL1/IFT122/TSC1/MTHFD1L/ALX1/CTHRC1/NPHP3/MKS1/IFT57	17
BP	GO:0061013	regulation of mRNA catabolic process	29/1616	199/18670	0.003819	0.1343	0.1245	DCP1A/ZC3H12A/SERBP1/PSME2/TNRC6B/METTL16/TBRG4/HSPA1A/EXOSC5/BTG2/ELAVL1/DHX34/DIS3/PSMD5/ZFP36L1/PSMA5/DCP2/RBM38/FTO/PSMA2/YWHAZ/GTPBP1/ZFP36L2/PSME4/YTHDF3/CNOT6L/UPF1/PSMB3/PSMD2	29
BP	GO:0010506	regulation of autophagy	43/1616	327/18670	0.003824	0.1343	0.1245	PIM2/DAP/CDK5/PHF23/ZC3H12A/PYCARD/RASIP1/PRKAB1/ZKSCAN3/MUL1/SH3GLB1/TRIB3/MAP3K7/PIK3CA/PRKAG2/TLK2/HAX1/GSK3A/CTSA/PARK7/EXOC8/SMCR8/GBA/SMURF1/BNIP3/WDR6/TRIM65/ATP6V1G1/IRGM/EP300/HK2/WDR24/SLC38A9/ATP6V0E1/TSC1/EIF2AK4/FOXK2/RAB1B/HTT/SPTLC2/ATP13A2/LAMTOR2/SIRT1	43
BP	GO:1901987	regulation of cell cycle phase transition	59/1616	480/18670	0.003849	0.1343	0.1245	CDK4/PTPN6/PRMT1/FOXN3/CARM1/ERCC2/CDK2AP2/CHEK2/MEN1/CCND3/ZNF830/DBF4/ANKRD17/DUSP1/CENPJ/MYO16/PAGR1/PSME2/PLCB1/CDKN2B/ODF2/CDKN1B/CSNK1E/ANAPC7/SFI1/BID/PRMT2/CSNK1D/BTG2/RPA2/KLF4/PSMD5/CDKN2D/ZFP36L1/DDB1/PSMA5/KIF14/GADD45A/ATAD5/SENP2/MAD2L1BP/PSMA2/ZNF16/ZFP36L2/EP300/PSME4/BRD4/MECP2/WNT10B/TFDP2/NDE1/CDC25B/CNOT6L/PSMB3/DYNLL1/GPR132/HAUS2/CDKN1A/PSMD2	59
BP	GO:1902108	regulation of mitochondrial membrane permeability involved in apoptotic process	13/1616	66/18670	0.00387	0.1343	0.1245	MOAP1/NMT1/HIP1R/MUL1/GSK3A/HSPA1A/BID/BNIP3/YWHAZ/TFDP2/MTRNR2L5/TP63/RHOT2	13
BP	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	20/1616	122/18670	0.003998	0.1378	0.1278	SOCS4/NFE2L2/TRIB3/TLK2/ZFAND2A/GSK3A/PARK7/FBXO22/CSNK1E/GBA/HSPA1A/CSNK1D/CEBPA/GLMN/USP5/HERPUD1/WNT10B/VCP/MAP1A/SOCS5	20
BP	GO:0046653	tetrahydrofolate metabolic process	6/1616	19/18670	0.004212	0.1427	0.1323	GART/MTHFS/GCH1/DHFR/MTHFD2L/MTHFD1L	6
BP	GO:0071243	cellular response to arsenic-containing substance	6/1616	19/18670	0.004212	0.1427	0.1323	ZC3H12A/ZFAND2A/ATF4/VCP/HNRNPA1/DAXX	6
BP	GO:0030183	B cell differentiation	21/1616	131/18670	0.00424	0.1427	0.1323	PTPN6/LRRC8A/ZBTB1/CD79B/PIK3R1/IRF2BP2/CD27/DNAJB9/ZFP36L1/MMP14/AICDA/CLCF1/ZFP36L2/EP300/MFNG/NHEJ1/JAK3/FNIP1/IFNA10/BCL6/ITM2A	21
BP	GO:0001843	neural tube closure	16/1616	90/18670	0.00425	0.1427	0.1323	SEMA4C/FZD6/TRAF6/BCL10/BMP4/TWIST1/VASP/GLMN/IFT122/TSC1/MTHFD1L/ALX1/CTHRC1/NPHP3/MKS1/IFT57	16
BP	GO:0009648	photoperiodism	7/1616	25/18670	0.004285	0.1427	0.1323	PER1/CRY2/SIK1/RBM4B/RBM4/FBXL3/PER3	7
BP	GO:0019430	removal of superoxide radicals	7/1616	25/18670	0.004285	0.1427	0.1323	NFE2L2/GCH1/PARK7/DHFR/NOS3/FANCC/FBLN5	7
BP	GO:0061136	regulation of proteasomal protein catabolic process	27/1616	183/18670	0.004325	0.1432	0.1328	SOCS4/SCO1/NFE2L2/TRIB3/TLK2/PSME2/ZFAND2A/GSK3A/PARK7/FBXO22/CSNK1E/GBA/HSPA1A/CSNK1D/TMTC3/CEBPA/GLMN/USP5/HERPUD1/GPX1/WNT10B/VCP/MAP1A/YOD1/SOCS5/ALAD/KCNE2	27
BP	GO:1901990	regulation of mitotic cell cycle phase transition	55/1616	444/18670	0.004375	0.144	0.1335	CDK4/PTPN6/PRMT1/FOXN3/CARM1/ERCC2/CDK2AP2/CHEK2/CCND3/ZNF830/ANKRD17/DUSP1/CENPJ/MYO16/PSME2/PLCB1/CDKN2B/ODF2/CDKN1B/CSNK1E/ANAPC7/SFI1/BID/PRMT2/CSNK1D/BTG2/RPA2/KLF4/PSMD5/CDKN2D/ZFP36L1/DDB1/PSMA5/KIF14/GADD45A/ATAD5/SENP2/MAD2L1BP/PSMA2/ZFP36L2/EP300/PSME4/BRD4/MECP2/WNT10B/TFDP2/NDE1/CDC25B/CNOT6L/PSMB3/DYNLL1/GPR132/HAUS2/CDKN1A/PSMD2	55
BP	GO:0034620	cellular response to unfolded protein	22/1616	140/18670	0.004446	0.1455	0.1349	YIF1A/NFE2L2/PIK3R1/BFAR/GSK3A/PPP1R15B/CREBRF/HSPA1A/DNAJB9/TSPYL2/SERP2/TATDN2/HERPUD1/EP300/ATF4/VCP/HSPA1L/DDX11/HSPA13/CTH/DAXX/YOD1	22
BP	GO:0002244	hematopoietic progenitor cell differentiation	25/1616	166/18670	0.004503	0.1465	0.1359	PTPN6/NOTCH1/SRF/ZBTB1/ERCC2/BATF/NFE2L2/CHD2/ARMC6/RBM47/PSME2/FSTL3/BMP4/PSMD5/PSMA5/SOS1/PSMA2/PSME4/FNIP1/ARL11/PSMB3/SLC7A6OS/ZBTB24/MEOX1/PSMD2	25
BP	GO:0048524	positive regulation of viral process	18/1616	107/18670	0.004644	0.1492	0.1384	CCNT1/TBC1D20/NOTCH1/TAF11/SMARCB1/POLR2D/IFIT1/VPS37B/POLR2H/PKN2/TRIM11/DDB1/TSG101/LGALS9/RSF1/CFL1/EP300/ZNF639	18
BP	GO:0000086	G2/M transition of mitotic cell cycle	34/1616	247/18670	0.004668	0.1492	0.1384	CDK4/FOXN3/CHEK2/ZNF830/CENPJ/PSME2/PLCB1/MNAT1/CDKN2B/ODF2/DNM2/CSNK1E/SFI1/CSNK1D/MASTL/PSMD5/PSMA5/KIF14/PSMA2/ABCB1/PSME4/BRD4/MECP2/WNT10B/NDE1/SKP2/CDC25B/PSMB3/DYNLL1/GPR132/KDM8/HAUS2/CDKN1A/PSMD2	34
BP	GO:2000106	regulation of leukocyte apoptotic process	15/1616	83/18670	0.004725	0.1492	0.1384	IRF7/PRELID1/CD27/BCL10/FADD/BMP4/LGALS14/TSC22D3/LGALS9/RAPGEF2/IRS2/JAK3/FNIP1/BCL6/SIRT1	15
BP	GO:0060606	tube closure	16/1616	91/18670	0.004752	0.1492	0.1384	SEMA4C/FZD6/TRAF6/BCL10/BMP4/TWIST1/VASP/GLMN/IFT122/TSC1/MTHFD1L/ALX1/CTHRC1/NPHP3/MKS1/IFT57	16
BP	GO:0033260	nuclear DNA replication	12/1616	60/18670	0.004758	0.1492	0.1384	POLD2/CHEK2/POLD4/ZNF830/DBF4/PRIM1/RPA2/AICDA/ATAD5/UPF1/BCL6/RPA1	12
BP	GO:1902110	positive regulation of mitochondrial membrane permeability involved in apoptotic process	12/1616	60/18670	0.004758	0.1492	0.1384	MOAP1/NMT1/HIP1R/MUL1/GSK3A/HSPA1A/BID/BNIP3/YWHAZ/TFDP2/TP63/RHOT2	12
BP	GO:1903706	regulation of hemopoiesis	58/1616	475/18670	0.004765	0.1492	0.1384	PIM1/CD83/IRF7/PTPN6/PRMT1/NOTCH1/NFKBIA/ROR2/ZBTB1/IL34/PRELID1/ATXN1L/ISG15/ZC3H12A/TRAF6/NFE2L2/CREBBP/THBS1/PIK3R1/CEACAM1/HAX1/PSME2/FSTL3/MYC/TNRC6B/CD27/RASSF2/ACVR1B/FADD/BMP4/HSPA1A/PSMD5/ZFP36L1/MMP14/PSMA5/IL12A/SOS1/LGALS9/PSMA2/MEIS2/ZNF16/CD46/LILRB3/ZFP36L2/EP300/GPR171/PSME4/RC3H2/JAK3/FNIP1/WDR61/PSMB3/BCL6/PNP/SOCS5/TOB2/PSMD2/TGFBR2	58
BP	GO:0050779	RNA destabilization	8/1616	32/18670	0.004941	0.153	0.1419	ZC3H12A/METTL16/ZFP36L1/FTO/ZFP36L2/YTHDF3/CNOT6L/UPF1	8
BP	GO:0006986	response to unfolded protein	26/1616	176/18670	0.004958	0.153	0.1419	YIF1A/DNAJB5/NFE2L2/THBS1/PIK3R1/BFAR/GSK3A/PPP1R15B/CREBRF/HSPA1A/DNAJB9/TSPYL2/SERP2/DNAJB1/TATDN2/HERPUD1/EP300/ATF4/VCP/DNAJA1/HSPA1L/DDX11/HSPA13/CTH/DAXX/YOD1	26
BP	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity	5/1616	14/18670	0.004971	0.153	0.1419	SOCS4/TSG101/CBLB/ZGPAT/SOCS5	5
BP	GO:0034976	response to endoplasmic reticulum stress	38/1616	285/18670	0.004993	0.153	0.1419	RNF103/SERINC3/NRBF2/YIF1A/TNFRSF10B/GET4/NFE2L2/THBS1/HM13/TRIB3/PIK3R1/TMEM117/UFC1/BFAR/ATP2A1/GSK3A/PPP1R15B/PARK7/CREBRF/HSPA1A/DNAJB9/TSPYL2/SERP2/BCL2L1/TMTC3/SGTB/TATDN2/HERPUD1/EP300/ATF4/VCP/DDX11/EIF2AK4/HSPA13/CTH/YOD1/UFM1/SIRT1	38
BP	GO:0033574	response to testosterone	9/1616	39/18670	0.005204	0.1587	0.1472	CDK4/NASP/THBS1/DUSP1/PSPH/GBA/GNRH1/CAD/SIRT1	9
BP	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	52/1616	419/18670	0.005279	0.1601	0.1485	RNF103/TOPORS/SOCS4/NFE2L2/FBXW4/TRIB3/TLK2/PSME2/ZFAND2A/BFAR/GSK3A/PARK7/FBXO22/SIAH2/CSNK1E/ANAPC7/GBA/HSPA1A/CSNK1D/DNAJB9/SMURF1/PSMD5/RBCK1/FBXO33/DDB1/PSMA5/KIF14/SGTB/CEBPA/ZNRF1/SPOPL/GLMN/PSMA2/USP5/FBXL3/HERPUD1/RMND5B/RNF4/TRIM2/PSME4/WNT10B/VCP/SPOP/SKP2/MAP1A/PSMB3/UBE3A/HSPA13/YOD1/SOCS5/PSMD2/SIRT1	52
BP	GO:0006779	porphyrin-containing compound biosynthetic process	7/1616	26/18670	0.005433	0.1609	0.1493	IREB2/SLC25A38/SRRD/RSAD1/IBA57/ALAD/SLC11A2	7
BP	GO:0007020	microtubule nucleation	7/1616	26/18670	0.005433	0.1609	0.1493	CENPJ/HSPA1A/CSNK1D/RANGRF/MECP2/NDE1/TUBGCP5	7
BP	GO:0006913	nucleocytoplasmic transport	44/1616	343/18670	0.005452	0.1609	0.1493	CTDSPL2/NUP50/NFKBIA/CDK5/RGS14/IPO13/POLR2D/TMCO6/ZC3H12A/STRADB/KPNA5/PIK3R1/DDX19B/TCF7L2/ENY2/NUP133/PARK7/FBXO22/FAM53C/BMP4/AAAS/NUP35/SMURF1/RBM4/RANBP6/SRSF11/SMN2/HTATIP2/CBLB/RGPD6/XPO4/SLU7/AKAP8L/FGF9/SRRM1/ANP32C/HNRNPA1/CSE1L/TSC1/PPM1A/WDR33/UPF1/GEMIN7/CDKN1A	44
BP	GO:0030521	androgen receptor signaling pathway	12/1616	61/18670	0.005467	0.1609	0.1493	PHB/FKBP4/PARK7/PRMT2/EP300/RNF4/SAFB2/DNAJA1/UBE3A/PMEPA1/DAXX/SIRT1	12
BP	GO:0010508	positive regulation of autophagy	19/1616	117/18670	0.005488	0.1609	0.1493	PIM2/ZC3H12A/MUL1/SH3GLB1/MAP3K7/GSK3A/PARK7/SMCR8/GBA/SMURF1/BNIP3/TRIM65/IRGM/HK2/TSC1/EIF2AK4/HTT/SPTLC2/SIRT1	19
BP	GO:0002320	lymphoid progenitor cell differentiation	6/1616	20/18670	0.005583	0.1609	0.1493	NOTCH1/ZBTB1/BATF/BMP4/SOS1/FNIP1	6
BP	GO:0033617	mitochondrial respiratory chain complex IV assembly	6/1616	20/18670	0.005583	0.1609	0.1493	COA5/COA3/SCO1/BCS1L/SCO2/COX19	6
BP	GO:0097503	sialylation	6/1616	20/18670	0.005583	0.1609	0.1493	ST6GAL1/ST6GALNAC4/ST3GAL3/ST3GAL5/ST3GAL2/ST6GALNAC1	6
BP	GO:0002819	regulation of adaptive immune response	24/1616	160/18670	0.005584	0.1609	0.1493	IRF7/PTPN6/ZBTB1/ZC3H12A/PYCARD/TRAF6/TNFAIP3/RSAD2/MAP3K7/CEACAM1/FADD/IL12A/ATAD5/CLCF1/IL27RA/HLA-H/RC3H2/JAK3/HLA-A/EIF2AK4/BCL6/HLA-C/SOCS5/SIRT1	24
BP	GO:0021915	neural tube development	24/1616	160/18670	0.005584	0.1609	0.1493	GORAB/NOTCH1/SEMA4C/FZD6/TMEM107/TRAF6/NUP133/BCL10/BMP4/TWIST1/VASP/ZFP36L1/GLMN/CFL1/IFT122/TSC1/MTHFD1L/ALX1/CTHRC1/GPR161/NPHP3/GSC/MKS1/IFT57	24
BP	GO:0070227	lymphocyte apoptotic process	13/1616	69/18670	0.005744	0.1644	0.1524	PRELID1/DFFA/CD27/BCL10/FADD/BMP4/LGALS14/TSC22D3/LGALS9/IRS2/JAK3/FNIP1/BCL6	13
BP	GO:0050821	protein stabilization	26/1616	178/18670	0.00576	0.1644	0.1524	PIM1/CCT5/AAK1/PIM2/PHB/CHEK2/HIP1R/MUL1/PEX6/CCT6A/PIK3R1/GRN/PDCD10/PARK7/RASSF2/HSPA1A/WDR81/FKBPL/ATP1B2/IRGM/EP300/PER3/WNT10B/TSC1/APOA1/CDKN1A	26
BP	GO:0045444	fat cell differentiation	31/1616	223/18670	0.005795	0.1646	0.1526	CARM1/NR4A2/CBY1/ZC3H12A/INSIG1/TRIB3/PLCB1/TCF7L2/RORA/C1QTNF3/BSCL2/NAPEPLD/KLF4/BNIP3/ZFP36L1/LRG1/CEBPA/SENP2/METRNL/ATAT1/FTO/ASXL2/ZFP36L2/EP300/NR1D1/MEX3C/ASXL1/ADRB1/GPX1/WNT10B/SIRT1	31
BP	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	14/1616	77/18670	0.005892	0.1652	0.1532	EGLN2/HIF1AN/NOTCH1/EGLN3/NFE2L2/CREBBP/PSME2/PSMD5/PSMA5/PSMA2/EP300/PSME4/PSMB3/PSMD2	14
BP	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	14/1616	77/18670	0.005892	0.1652	0.1532	ENDOG/RPP14/EDC3/TSEN15/ABT1/RNASEH1/ZC3H12A/POP1/DICER1/MRPL44/NOL9/RPP40/TSN/UTP23	14
BP	GO:0006476	protein deacetylation	16/1616	93/18670	0.005902	0.1652	0.1532	PER1/AKAP8/PHB/CAMK2D/MIER1/SFPQ/MORF4L1/RBM14/HDAC2/EP300/AKAP8L/BAZ2A/BEX4/BCL6/SIRT5/SIRT1	16
BP	GO:0070232	regulation of T cell apoptotic process	8/1616	33/18670	0.006036	0.1681	0.1559	PRELID1/CD27/FADD/BMP4/LGALS14/TSC22D3/LGALS9/JAK3	8
BP	GO:0070231	T cell apoptotic process	10/1616	47/18670	0.006106	0.1692	0.1569	PRELID1/DFFA/CD27/BCL10/FADD/BMP4/LGALS14/TSC22D3/LGALS9/JAK3	10
BP	GO:0043433	negative regulation of DNA-binding transcription factor activity	25/1616	170/18670	0.006133	0.1692	0.1569	PIM1/MXI1/NFKBIE/PARP10/NFKBIA/DAP/FZD6/ZC3H12A/PYCARD/MEN1/SIK1/TNFAIP3/TCF7L2/SRI/TWIST1/PRMT2/KLF4/HDAC2/RBCK1/CCDC22/G3BP2/EIF2AK4/RLIM/GFI1/SIRT1	25
BP	GO:0006367	transcription initiation from RNA polymerase II promoter	27/1616	188/18670	0.006238	0.1702	0.1578	CDK4/MED26/NOTCH1/NRBF2/GTF2H5/SRF/ERCC2/NR4A2/TAF11/POLR2D/NR1D2/CREBBP/NR3C2/POLR2H/RORA/MNAT1/RXRB/GTF2H4/THRA/MED6/TAF15/NR1D1/MECP2/WNT10B/TAF13/NR3C1/CDKN1A	27
BP	GO:0002753	cytoplasmic pattern recognition receptor signaling pathway	12/1616	62/18670	0.006257	0.1702	0.1578	IRF7/NFKBIA/TRAF6/TNFAIP3/ANKRD17/MAP3K7/HSPA1A/ZCCHC3/GPATCH3/RNF125/IRGM/DDX58	12
BP	GO:1902686	mitochondrial outer membrane permeabilization involved in programmed cell death	12/1616	62/18670	0.006257	0.1702	0.1578	MOAP1/NMT1/HIP1R/MUL1/GSK3A/HSPA1A/BID/BNIP3/YWHAZ/TFDP2/TP63/RHOT2	12
BP	GO:0051169	nuclear transport	44/1616	346/18670	0.006364	0.1723	0.1598	CTDSPL2/NUP50/NFKBIA/CDK5/RGS14/IPO13/POLR2D/TMCO6/ZC3H12A/STRADB/KPNA5/PIK3R1/DDX19B/TCF7L2/ENY2/NUP133/PARK7/FBXO22/FAM53C/BMP4/AAAS/NUP35/SMURF1/RBM4/RANBP6/SRSF11/SMN2/HTATIP2/CBLB/RGPD6/XPO4/SLU7/AKAP8L/FGF9/SRRM1/ANP32C/HNRNPA1/CSE1L/TSC1/PPM1A/WDR33/UPF1/GEMIN7/CDKN1A	44
BP	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	17/1616	102/18670	0.00642	0.173	0.1604	CDK4/CCNT1/CCNJ/MEN1/CCND3/TNFAIP3/MNAT1/ACTB/CDKN2B/CDKN1B/CDKN2D/CEBPA/GADD45A/CCNL1/LATS2/CDKN1A/CDK5RAP1	17
BP	GO:0033143	regulation of intracellular steroid hormone receptor signaling pathway	14/1616	78/18670	0.006623	0.1751	0.1624	PER1/CRY2/PHB/CARM1/PAGR1/PARK7/PRMT2/GPAM/EP300/SAFB2/SKP2/TP63/UFM1/SIRT1	14
BP	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	15/1616	86/18670	0.006631	0.1751	0.1624	PDCD6/DAP/EGLN3/TNFRSF10B/PYCARD/HIP1R/MUL1/CASP9/CASP10/CTSH/TNFSF10/FADD/BID/VCP/IFT57	15
BP	GO:0043551	regulation of phosphatidylinositol 3-kinase activity	11/1616	55/18670	0.006735	0.1751	0.1624	CISH/SOCS3/PIK3R1/WDR91/SOCS2/WDR81/P2RY12/AGAP2/KLF4/ATG14/SOCS5	11
BP	GO:0006730	one-carbon metabolic process	7/1616	27/18670	0.006796	0.1751	0.1624	MAT2B/MTHFS/AHCY/DHFR/MTHFD2L/MAT2A/MTHFD1L	7
BP	GO:0071450	cellular response to oxygen radical	7/1616	27/18670	0.006796	0.1751	0.1624	NFE2L2/GCH1/PARK7/DHFR/NOS3/FANCC/FBLN5	7
BP	GO:0071451	cellular response to superoxide	7/1616	27/18670	0.006796	0.1751	0.1624	NFE2L2/GCH1/PARK7/DHFR/NOS3/FANCC/FBLN5	7
BP	GO:0002483	antigen processing and presentation of endogenous peptide antigen	5/1616	15/18670	0.006932	0.1751	0.1624	ERAP2/TAP1/HLA-H/HLA-A/HLA-C	5
BP	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	5/1616	15/18670	0.006932	0.1751	0.1624	CLP1/TSEN15/C2orf49/FAM98B/TRPT1	5
BP	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	5/1616	15/18670	0.006932	0.1751	0.1624	ERAP2/TAP1/HLA-H/HLA-A/HLA-C	5
BP	GO:0042559	pteridine-containing compound biosynthetic process	5/1616	15/18670	0.006932	0.1751	0.1624	GART/MTHFS/GCH1/DHFR/MTHFD1L	5
BP	GO:0042921	glucocorticoid receptor signaling pathway	5/1616	15/18670	0.006932	0.1751	0.1624	PER1/CRY2/PHB/RBM14/NR3C1	5
BP	GO:0098840	protein transport along microtubule	5/1616	15/18670	0.006932	0.1751	0.1624	CAMSAP3/SFPQ/MAPK8IP3/RAB27B/MAP1A	5
BP	GO:0099118	microtubule-based protein transport	5/1616	15/18670	0.006932	0.1751	0.1624	CAMSAP3/SFPQ/MAPK8IP3/RAB27B/MAP1A	5
BP	GO:0034404	nucleobase-containing small molecule biosynthetic process	31/1616	226/18670	0.007028	0.1751	0.1624	NUP50/HK1/DTYMK/PGAM4/CNP/PRKAG2/NUDT9/NUP133/NUDT4/ASPDH/AAAS/NUP35/NUDT1/PDE7A/PFKFB3/DCTPP1/GALK1/PGK2/HK2/GPX1/PFKL/DHODH/VCP/CAD/SMUG1/FOXK2/PNP/PFKFB4/PFKP/NT5C1A/ENTPD5	31
BP	GO:0051495	positive regulation of cytoskeleton organization	31/1616	226/18670	0.007028	0.1751	0.1624	CDK5/CFL2/PYCARD/JMY/HIP1R/WHAMMP3/WHAMM/ARPC1B/SWAP70/WDR1/CENPJ/HAX1/GMFB/RICTOR/CDKN1B/SPIRE2/HSPA1A/VASP/CORO1B/CFL1/PRKCE/CORO1A/MECP2/FCHSD1/TSC1/WASL/GPSM2/FMN1/NCKAP1/ARPC5/APOA1	31
BP	GO:0016049	cell growth	58/1616	484/18670	0.007042	0.1751	0.1624	CISH/EGLN2/BRAT1/HBEGF/OSGIN2/ATAD3A/PHB/CDK5/SERTAD2/GNG4/SRF/SEMA4C/CAMK2D/CXCR4/ADIPOR2/MUL1/SUPV3L1/RPS6KA1/CEACAM1/TRPV2/SOCS2/SEMA4F/GSK3A/ACVR1B/CDKN1B/DNM2/HSPA1A/PRMT2/NLGN3/SMURF1/TWF2/TSPYL2/CDKN2D/BST2/MMP14/KIF14/TSG101/CDKN2AIP/ADNP2/LPAR3/OSGIN1/MEX3C/CRABP2/PLXNA4/CXCL16/BAP1/LLPH/KRT17/EIF2AK4/BCL6/BIN3/ARHGAP4/CDKN1A/LAMTOR2/ZNF639/SIRT1/FBLN5/TGFBR2	58
BP	GO:0035601	protein deacylation	17/1616	103/18670	0.007086	0.1751	0.1624	PER1/AKAP8/PHB/CAMK2D/MIER1/SFPQ/MORF4L1/RBM14/ABHD13/HDAC2/EP300/AKAP8L/BAZ2A/BEX4/BCL6/SIRT5/SIRT1	17
BP	GO:0044282	small molecule catabolic process	54/1616	445/18670	0.007116	0.1751	0.1624	CPT1B/HMGCL/NAGK/ADO/HK1/CPT1C/ETFA/HYAL3/XYLB/ALDH8A1/BDH1/MTHFS/AHCY/AMDHD1/BCAT1/DDAH2/TKTL1/GNPDA1/NUDT9/SORD/FUT4/GSK3A/SLC27A4/GCAT/GALK2/TWIST1/CYP4F12/PECR/NOS3/NUDT1/ALDH4A1/PLA2G15/AICDA/GALK1/BCKDK/NUDT19/GALT/HK2/IRS2/PFKL/FAH/ETFB/HGD/SULT1B1/FOXK2/LIPE/PNP/CTH/PFKP/DLD/NT5C1A/MCAT/GK/ENTPD5	54
BP	GO:0016052	carbohydrate catabolic process	28/1616	199/18670	0.007171	0.1751	0.1624	NUP50/HK1/PGAM4/XYLB/PPP1R3D/NAGA/MAN2C1/PRKAG2/TKTL1/SORD/FUT4/GSK3A/NUP133/GALK2/AAAS/NUP35/PFKFB3/GM2A/GALK1/PGK2/GALT/HK2/PFKL/FOXK2/PFKFB4/PFKP/GK/ENTPD5	28
BP	GO:0001558	regulation of cell growth	51/1616	416/18670	0.007198	0.1751	0.1624	CISH/EGLN2/BRAT1/HBEGF/OSGIN2/ATAD3A/PHB/CDK5/SERTAD2/GNG4/SRF/SEMA4C/CAMK2D/CXCR4/ADIPOR2/MUL1/SUPV3L1/RPS6KA1/CEACAM1/TRPV2/SOCS2/SEMA4F/GSK3A/ACVR1B/CDKN1B/DNM2/HSPA1A/SMURF1/TWF2/TSPYL2/CDKN2D/BST2/MMP14/KIF14/TSG101/CDKN2AIP/ADNP2/LPAR3/OSGIN1/CRABP2/PLXNA4/CXCL16/BAP1/KRT17/BCL6/ARHGAP4/CDKN1A/LAMTOR2/ZNF639/SIRT1/FBLN5	51
BP	GO:0030099	myeloid cell differentiation	51/1616	416/18670	0.007198	0.1751	0.1624	ABI1/IRF7/PTPN6/PRMT1/NFKBIA/SRF/ROR2/ERCC2/IL34/BATF/ISG15/TRAF6/CREBBP/THBS1/CASP9/WDR1/PIK3R1/CEACAM1/PRDX3/HAX1/IREB2/FSTL3/MYC/TNRC6B/L3MBTL3/RASSF2/CDKN2B/ACVR1B/SNRK/FADD/BMP4/JUNB/HSPA1A/SLC25A38/FLI1/ZFP36L1/SH2B3/CEBPA/THRA/MEIS2/ZNF16/LILRB3/EP300/GPR171/JAK3/WDR61/BCL6/TOB2/SIRT1/TGFBR2/SLC11A2	51
BP	GO:1903052	positive regulation of proteolysis involved in cellular protein catabolic process	19/1616	120/18670	0.007227	0.1751	0.1624	SOCS4/NFE2L2/TRIB3/ZFAND2A/GSK3A/FBXO22/CSNK1E/GBA/HSPA1A/CSNK1D/SMURF1/TMTC3/CEBPA/CCDC22/USP5/HERPUD1/VCP/SOCS5/KCNE2	19
BP	GO:0006293	nucleotide-excision repair, preincision complex stabilization	6/1616	21/18670	0.007252	0.1751	0.1624	GTF2H5/ERCC2/RPA2/DDB1/GTF2H4/RPA1	6
BP	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion	6/1616	21/18670	0.007252	0.1751	0.1624	GTF2H5/ERCC2/RPA2/DDB1/GTF2H4/RPA1	6
BP	GO:0055093	response to hyperoxia	6/1616	21/18670	0.007252	0.1751	0.1624	CDK4/POLB/BNIP3/HDAC2/COL1A1/CDKN1A	6
BP	GO:0019985	translesion synthesis	9/1616	41/18670	0.007359	0.1769	0.164	PARP10/POLD2/ZBTB1/ISG15/POLD4/SPRTN/RPA2/VCP/RPA1	9
BP	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	14/1616	79/18670	0.007425	0.1777	0.1648	IKBKB/SNAP23/PSME2/PSMD5/TAP1/PSMA5/IFI30/PSMA2/HLA-H/PSME4/HLA-A/PSMB3/HLA-C/PSMD2	14
BP	GO:0032271	regulation of protein polymerization	30/1616	218/18670	0.007563	0.1783	0.1654	CAMSAP3/PYCARD/JMY/HIP1R/WHAMMP3/WHAMM/ARPC1B/TPPP3/HAX1/FKBP4/GMFB/RICTOR/CDKN1B/SPIRE2/HSPA1A/TWF2/VASP/CAPZB/CORO1B/PRKCE/RANGRF/TWF1/TMSB4Y/CORO1A/MECP2/FCHSD1/WASL/FMN1/NCKAP1/ARPC5	30
BP	GO:0008154	actin polymerization or depolymerization	29/1616	209/18670	0.007626	0.1783	0.1654	ABI1/CFL2/PYCARD/JMY/HIP1R/WHAMMP3/WHAMM/ARPC1B/SWAP70/WDR1/HAX1/GMFB/RICTOR/SPIRE2/TWF2/VASP/CAPZB/CORO1B/CFL1/PRKCE/PSTPIP2/TWF1/TMSB4Y/CORO1A/FCHSD1/WASL/FMN1/NCKAP1/ARPC5	29
BP	GO:0090305	nucleic acid phosphodiester bond hydrolysis	39/1616	302/18670	0.007641	0.1783	0.1654	ENDOG/POLD2/RPP14/GTF2H5/EDC3/ERCC2/DCP1A/TSEN15/ABT1/RNASEH1/APEX2/ZC3H12A/POLD4/DFFA/POP1/EXD3/DICER1/EXOSC5/RPA2/DIS3/ASTE1/DDB1/DCP2/MRPL44/TATDN2/NOL9/ATAD5/GTF2H4/TOE1/REXO1/RPP40/CNOT6L/RPA1/TSN/MUS81/REXO2/ISG20/UTP23/TATDN3	39
BP	GO:0006002	fructose 6-phosphate metabolic process	4/1616	10/18670	0.007672	0.1783	0.1654	TALDO1/GFPT2/PFKL/PFKP	4
BP	GO:0032025	response to cobalt ion	4/1616	10/18670	0.007672	0.1783	0.1654	CASP9/BNIP3/ALAD/D2HGDH	4
BP	GO:0046148	pigment biosynthetic process	11/1616	56/18670	0.007742	0.1783	0.1654	GART/IREB2/SLC25A38/SRRD/RAPGEF2/IBA57/DDT/CTNS/MTHFD1L/ALAD/SLC11A2	11
BP	GO:0071887	leukocyte apoptotic process	17/1616	104/18670	0.007806	0.1783	0.1654	IRF7/PRELID1/CASP9/DFFA/CD27/BCL10/FADD/BMP4/LGALS14/TSC22D3/LGALS9/RAPGEF2/IRS2/JAK3/FNIP1/BCL6/SIRT1	17
BP	GO:0098732	macromolecule deacylation	17/1616	104/18670	0.007806	0.1783	0.1654	PER1/AKAP8/PHB/CAMK2D/MIER1/SFPQ/MORF4L1/RBM14/ABHD13/HDAC2/EP300/AKAP8L/BAZ2A/BEX4/BCL6/SIRT5/SIRT1	17
BP	GO:1901800	positive regulation of proteasomal protein catabolic process	17/1616	104/18670	0.007806	0.1783	0.1654	SOCS4/NFE2L2/TRIB3/ZFAND2A/GSK3A/FBXO22/CSNK1E/GBA/HSPA1A/CSNK1D/TMTC3/CEBPA/USP5/HERPUD1/VCP/SOCS5/KCNE2	17
BP	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	17/1616	104/18670	0.007806	0.1783	0.1654	TNFRSF10B/STRADB/TNFAIP3/THBS1/TCF7L2/TNFSF10/PARK7/SIAH2/FADD/BMP4/HSPA1A/NOS3/BCL2L1/FAIM2/GPX1/RAF1/HTT	17
BP	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	47/1616	379/18670	0.007818	0.1783	0.1654	AAR2/MBNL2/CLP1/PTBP1/USP4/RBM25/WTAP/SNRPA1/POLR2D/SNIP1/DHX16/PTBP2/SFPQ/SF3A1/POLR2H/METTL16/CHERP/RBM19/ELAVL1/RBM4B/SRRT/ESRP2/SNRNP25/RBM4/ZC3H10/SF3A2/SRSF11/SMN2/RBM3/TGS1/HNRNPUL1/PPIL1/SLU7/PQBP1/CWF19L1/SRRM1/PHF5A/SRSF10/HNRNPL/XAB2/HNRNPA1/WDR33/KHDRBS3/GEMIN7/RBM17/HNRNPH3/GPATCH1	47
BP	GO:0000398	mRNA splicing, via spliceosome	47/1616	379/18670	0.007818	0.1783	0.1654	AAR2/MBNL2/CLP1/PTBP1/USP4/RBM25/WTAP/SNRPA1/POLR2D/SNIP1/DHX16/PTBP2/SFPQ/SF3A1/POLR2H/METTL16/CHERP/RBM19/ELAVL1/RBM4B/SRRT/ESRP2/SNRNP25/RBM4/ZC3H10/SF3A2/SRSF11/SMN2/RBM3/TGS1/HNRNPUL1/PPIL1/SLU7/PQBP1/CWF19L1/SRRM1/PHF5A/SRSF10/HNRNPL/XAB2/HNRNPA1/WDR33/KHDRBS3/GEMIN7/RBM17/HNRNPH3/GPATCH1	47
BP	GO:0030968	endoplasmic reticulum unfolded protein response	19/1616	121/18670	0.007897	0.1787	0.1657	YIF1A/NFE2L2/PIK3R1/BFAR/GSK3A/PPP1R15B/CREBRF/DNAJB9/TSPYL2/SERP2/TATDN2/HERPUD1/EP300/ATF4/VCP/DDX11/HSPA13/CTH/YOD1	19
BP	GO:0046718	viral entry into host cell	19/1616	121/18670	0.007897	0.1787	0.1657	SLC20A2/IFITM2/HYAL3/CXCR4/SLC52A2/SLC1A5/SIVA1/VPS18/CDHR3/HSPA1A/TRIM11/DYNLT1/IFITM1/IFITM3/LGALS9/CD46/SELPLG/HAVCR1/ZNF639	19
BP	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	16/1616	96/18670	0.008039	0.18	0.1669	MR1/IKBKB/ERAP2/SNAP23/PSME2/PSMD5/TAP1/PSMA5/IFI30/PSMA2/HLA-H/PSME4/HLA-A/PSMB3/HLA-C/PSMD2	16
BP	GO:0033108	mitochondrial respiratory chain complex assembly	16/1616	96/18670	0.008039	0.18	0.1669	NDUFS7/COA5/LYRM7/NDUFS2/NDUFA12/COA3/SCO1/BCS1L/NDUFB8/SCO2/NDUFAF3/COX19/NDUFB11/NDUFB2/TIMMDC1/NDUFB10	16
BP	GO:0032535	regulation of cellular component size	46/1616	370/18670	0.008067	0.18	0.1669	CDK4/CDK5/SRF/LRRC8A/SEMA4C/CFL2/PYCARD/JMY/KCNN4/HIP1R/WHAMMP3/WHAMM/ARPC1B/SWAP70/WDR1/TRPV2/HAX1/SEMA4F/VAV1/GMFB/RICTOR/DNM2/SPIRE2/PEX11B/AKT1S1/TWF2/CDHR5/VASP/CAPZB/CORO1B/CFL1/PRKCE/TWF1/LPAR3/TMSB4Y/CORO1A/CRABP2/PLXNA4/FCHSD1/TSC1/WASL/ARHGAP4/FMN1/NCKAP1/ARPC5/ATP13A2	46
BP	GO:0035794	positive regulation of mitochondrial membrane permeability	12/1616	64/18670	0.008108	0.18	0.1669	MOAP1/NMT1/HIP1R/MUL1/GSK3A/HSPA1A/BID/BNIP3/YWHAZ/TFDP2/TP63/RHOT2	12
BP	GO:0043550	regulation of lipid kinase activity	12/1616	64/18670	0.008108	0.18	0.1669	CISH/NRBF2/SOCS3/PIK3R1/WDR91/SOCS2/WDR81/P2RY12/AGAP2/KLF4/ATG14/SOCS5	12
BP	GO:1903747	regulation of establishment of protein localization to mitochondrion	13/1616	72/18670	0.00828	0.1831	0.1698	RAC2/NMT1/PDCD5/SH3GLB1/HAX1/GSK3A/BID/YWHAZ/DNAJA1/TFDP2/BAP1/HSPA1L/TP63	13
BP	GO:0002831	regulation of response to biotic stimulus	21/1616	139/18670	0.008421	0.1855	0.172	PPM1B/ZC3H12A/PYCARD/IFIT1/TRAF6/TNFAIP3/ANKRD17/MUL1/DTX3L/CEACAM1/GRN/ZCCHC3/IL12A/RNF26/GPATCH3/RNF125/MICB/PQBP1/EIF2AK4/DDX58/TSPAN32	21
BP	GO:0001841	neural tube formation	17/1616	105/18670	0.008584	0.1884	0.1747	SEMA4C/FZD6/TRAF6/BCL10/BMP4/TWIST1/VASP/GLMN/CFL1/IFT122/TSC1/MTHFD1L/ALX1/CTHRC1/NPHP3/MKS1/IFT57	17
BP	GO:1902806	regulation of cell cycle G1/S phase transition	28/1616	202/18670	0.008752	0.1913	0.1774	CDK4/PTPN6/PRMT1/CARM1/CDK2AP2/CHEK2/MEN1/CCND3/ANKRD17/MYO16/PAGR1/PSME2/PLCB1/CDKN2B/CDKN1B/BID/PRMT2/BTG2/RPA2/KLF4/CDKN2D/KIF14/GADD45A/SENP2/EP300/TFDP2/CNOT6L/CDKN1A	28
BP	GO:2000045	regulation of G1/S transition of mitotic cell cycle	26/1616	184/18670	0.008833	0.1924	0.1784	CDK4/PTPN6/PRMT1/CARM1/CDK2AP2/CHEK2/CCND3/ANKRD17/MYO16/PSME2/PLCB1/CDKN2B/CDKN1B/BID/PRMT2/BTG2/RPA2/KLF4/CDKN2D/KIF14/GADD45A/SENP2/EP300/TFDP2/CNOT6L/CDKN1A	26
BP	GO:0000375	RNA splicing, via transesterification reactions	47/1616	382/18670	0.008996	0.1952	0.181	AAR2/MBNL2/CLP1/PTBP1/USP4/RBM25/WTAP/SNRPA1/POLR2D/SNIP1/DHX16/PTBP2/SFPQ/SF3A1/POLR2H/METTL16/CHERP/RBM19/ELAVL1/RBM4B/SRRT/ESRP2/SNRNP25/RBM4/ZC3H10/SF3A2/SRSF11/SMN2/RBM3/TGS1/HNRNPUL1/PPIL1/SLU7/PQBP1/CWF19L1/SRRM1/PHF5A/SRSF10/HNRNPL/XAB2/HNRNPA1/WDR33/KHDRBS3/GEMIN7/RBM17/HNRNPH3/GPATCH1	47
BP	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	12/1616	65/18670	0.009181	0.196	0.1818	MBNL2/PTBP1/RBM25/WTAP/RBM19/RBM4B/RBM4/ZC3H10/SRSF10/HNRNPL/HNRNPA1/RBM17	12
BP	GO:0006783	heme biosynthetic process	6/1616	22/18670	0.009255	0.196	0.1818	IREB2/SLC25A38/SRRD/IBA57/ALAD/SLC11A2	6
BP	GO:0032069	regulation of nuclease activity	6/1616	22/18670	0.009255	0.196	0.1818	DFFA/OAS2/HSPA1A/DDX11/OAS1/SIRT1	6
BP	GO:0001701	in utero embryonic development	46/1616	373/18670	0.009293	0.196	0.1818	ENDOG/PRMT1/NASP/NOTCH1/SRF/MYH10/ERCC2/BYSL/CAMSAP3/TRAF6/NMT1/ZNF830/SOCS3/HM13/POLB/CIR1/VASH1/SLC39A1/MYO1E/ACTL6A/PSPH/SLC25A20/TANC2/ACVR1B/MED21/SLC30A1/TWIST1/JUNB/NOS3/APBA3/BCL2L1/SMPD4/ZFP36L1/CEBPA/ZNF568/SENP2/RRN3/GATA6/MFNG/XAB2/CCNB1IP1/TET1/NSUN2/SBDS/KRT8/TGFBR2	46
BP	GO:0000394	RNA splicing, via endonucleolytic cleavage and ligation	5/1616	16/18670	0.009374	0.196	0.1818	CLP1/TSEN15/C2orf49/FAM98B/TRPT1	5
BP	GO:0031958	corticosteroid receptor signaling pathway	5/1616	16/18670	0.009374	0.196	0.1818	PER1/CRY2/PHB/RBM14/NR3C1	5
BP	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation	5/1616	16/18670	0.009374	0.196	0.1818	HIP1R/GMFB/CORO1B/WASL/NCKAP1	5
BP	GO:0045623	negative regulation of T-helper cell differentiation	5/1616	16/18670	0.009374	0.196	0.1818	ZC3H12A/RC3H2/JAK3/BCL6/SOCS5	5
BP	GO:1902001	fatty acid transmembrane transport	5/1616	16/18670	0.009374	0.196	0.1818	CPT1B/THBS1/PRKAG2/SLC25A20/IRS2	5
BP	GO:2000369	regulation of clathrin-dependent endocytosis	5/1616	16/18670	0.009374	0.196	0.1818	AAK1/HIP1R/DNM2/TNK2/WASL	5
BP	GO:1904029	regulation of cyclin-dependent protein kinase activity	17/1616	106/18670	0.009422	0.1963	0.1821	CDK4/CCNT1/CCNJ/MEN1/CCND3/TNFAIP3/MNAT1/ACTB/CDKN2B/CDKN1B/CDKN2D/CEBPA/GADD45A/CCNL1/LATS2/CDKN1A/CDK5RAP1	17
BP	GO:0030323	respiratory tube development	25/1616	176/18670	0.009471	0.1966	0.1824	NOTCH1/SRF/ATXN1L/HECA/ASCL1/FSTL3/CTSH/BMP4/FLT4/NOS3/ESRP2/MMP14/CEBPA/DHCR7/ITGA3/THRA/GATA6/EP300/ASXL1/RC3H2/FGF9/HSD11B1/NPHP3/TRAF4/TGFBR2	25
BP	GO:0046854	phosphatidylinositol phosphorylation	10/1616	50/18670	0.009564	0.1979	0.1835	CISH/PI4KAP1/SOCS3/PIK3R1/PIK3CA/SOCS2/IP6K1/IMPAD1/BPNT1/SOCS5	10
BP	GO:0045088	regulation of innate immune response	54/1616	452/18670	0.009613	0.1982	0.1838	IRF7/PTPN6/NFKBIA/IKBKB/PYCARD/TLR5/TRAF6/TREML2/SOCS3/MAPKAPK3/TNFAIP3/CREBBP/RSAD2/ANKRD17/MUL1/SFPQ/UNC93B1/MAP3K7/CEACAM1/GRN/PSME2/RBM14/VAV1/BCL10/FADD/HSPA1A/PSMD5/IL18RAP/PSMA5/ZCCHC3/IL12A/RAB11FIP2/OTUD4/GPATCH3/LGALS9/PRKCE/PSMA2/TRAFD1/RNF125/MICA/MUCL1/IRGM/EP300/CTSK/MICB/NR1D1/PSME4/PQBP1/YTHDF3/PSMB3/RAF1/DDX58/GFI1/PSMD2	54
BP	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	20/1616	132/18670	0.009664	0.1985	0.1841	PDCD6/DAP/EGLN3/TNFRSF10B/PYCARD/PDCD5/HIP1R/MUL1/CASP9/CASP10/MYC/CTSH/TNFSF10/BCL10/FADD/BID/LGALS9/VCP/SIRT1/IFT57	20
BP	GO:1904375	regulation of protein localization to cell periphery	18/1616	115/18670	0.009864	0.2019	0.1873	GBP1/CDK5/CSK/PIK3R1/ACTB/BCL2L1/MMP14/RAB11FIP2/ITGA3/PRKCE/RANGRF/ACSL3/EPB41L2/GRASP/IQSEC2/PRKCI/GPSM2/SAPCD2	18
BP	GO:1902905	positive regulation of supramolecular fiber organization	28/1616	204/18670	0.009958	0.2026	0.1879	CFL2/PYCARD/JMY/HIP1R/WHAMMP3/WHAMM/ARPC1B/SWAP70/WDR1/GMFB/RICTOR/CDKN1B/SPIRE2/HSPA1A/VASP/CORO1B/CFL1/PRKCE/CORO1A/MECP2/GPX1/FCHSD1/TSC1/WASL/FMN1/NCKAP1/ARPC5/APOA1	28
BP	GO:0015931	nucleobase-containing compound transport	32/1616	241/18670	0.009968	0.2026	0.1879	HNRNPA1L2/NUP50/SLC35A2/POLR2D/MVP/TOMM20L/SFPQ/SLC25A6/SLC35A4/DDX19B/ENY2/NUP133/SLC25A36/SLC25A4/AAAS/NUP35/SLC29A2/ZFP36L1/G3BP2/SRSF11/TNKS/SENP2/SLU7/AKAP8L/SRRM1/SLC25A19/SIDT1/HNRNPA1/TSC1/WDR33/UPF1/TGFBR2	32
BP	GO:0035567	non-canonical Wnt signaling pathway	22/1616	150/18670	0.01002	0.2029	0.1881	ROR2/FZD6/MAP3K7/PSME2/PLCB1/PDE6G/TCF7L2/TNRC6B/AP2S1/CSNK1E/CSNK1D/SMURF1/PSMD5/PSMA5/ARHGEF19/PSMA2/PSME4/PSMB3/CTHRC1/NPHP3/PSMD2/MKS1	22
BP	GO:1903749	positive regulation of establishment of protein localization to mitochondrion	11/1616	58/18670	0.0101	0.203	0.1882	RAC2/NMT1/PDCD5/SH3GLB1/GSK3A/BID/YWHAZ/TFDP2/BAP1/HSPA1L/TP63	11
BP	GO:0043488	regulation of mRNA stability	25/1616	177/18670	0.01015	0.203	0.1882	DCP1A/ZC3H12A/SERBP1/PSME2/METTL16/TBRG4/HSPA1A/EXOSC5/ELAVL1/DIS3/PSMD5/ZFP36L1/PSMA5/DCP2/RBM38/FTO/PSMA2/YWHAZ/ZFP36L2/PSME4/YTHDF3/CNOT6L/UPF1/PSMB3/PSMD2	25
BP	GO:0000303	response to superoxide	7/1616	29/18670	0.01026	0.203	0.1882	NFE2L2/GCH1/PARK7/DHFR/NOS3/FANCC/FBLN5	7
BP	GO:0006294	nucleotide-excision repair, preincision complex assembly	7/1616	29/18670	0.01026	0.203	0.1882	GTF2H5/ERCC2/MNAT1/RPA2/DDB1/GTF2H4/RPA1	7
BP	GO:0031365	N-terminal protein amino acid modification	7/1616	29/18670	0.01026	0.203	0.1882	PPM1B/NMT1/CREBBP/PDF/NTMT1/EP300/PPM1A	7
BP	GO:2000171	negative regulation of dendrite development	7/1616	29/18670	0.01026	0.203	0.1882	CARM1/GSK3A/NLGN3/GORASP1/HDAC2/RAPGEF2/UBE3A	7
BP	GO:0034644	cellular response to UV	14/1616	82/18670	0.0103	0.203	0.1882	SDE2/ZBTB1/HYAL3/CREBBP/CASP9/PIK3R1/MYC/DDB1/EP300/ATF4/MFAP4/EIF2AK4/CDKN1A/SIRT1	14
BP	GO:0051702	interaction with symbiont	14/1616	82/18670	0.0103	0.203	0.1882	CCNT1/TBC1D20/TAF11/SMARCB1/ZC3H12A/AZU1/RAB9A/NAPEPLD/DDB1/CFL1/EP300/GPX1/EIF2AK4/ZNF639	14
BP	GO:1905710	positive regulation of membrane permeability	12/1616	66/18670	0.01036	0.2035	0.1887	MOAP1/NMT1/HIP1R/MUL1/GSK3A/HSPA1A/BID/BNIP3/YWHAZ/TFDP2/TP63/RHOT2	12
BP	GO:0006520	cellular amino acid metabolic process	45/1616	366/18670	0.01054	0.2062	0.1912	EGLN2/PSAT1/SERINC3/HMGCL/GART/ADO/EGLN3/DALRD3/ALDH8A1/MTHFS/AHCY/AMDHD1/BCAT1/DDAH2/ACY1/PSME2/SLC3A1/PSPH/GFPT2/PARK7/GCAT/SEPSECS/MTHFD2L/NOS3/HPDL/PSMD5/DARS2/ALDH4A1/PSMA5/ALDH18A1/PSMA2/BCKDK/ATF4/PSME4/WARS2/MECP2/CTNS/FAH/HGD/CAD/ASS1/PSMB3/CTH/DLD/PSMD2	45
BP	GO:0002218	activation of innate immune response	40/1616	319/18670	0.01121	0.2161	0.2005	IRF7/NFKBIA/IKBKB/PYCARD/TLR5/TRAF6/MAPKAPK3/TNFAIP3/CREBBP/RSAD2/ANKRD17/SFPQ/UNC93B1/MAP3K7/PSME2/RBM14/BCL10/FADD/HSPA1A/PSMD5/PSMA5/ZCCHC3/RAB11FIP2/OTUD4/GPATCH3/PRKCE/PSMA2/RNF125/MUCL1/IRGM/EP300/CTSK/NR1D1/PSME4/PQBP1/PSMB3/RAF1/DDX58/GFI1/PSMD2	40
BP	GO:0070475	rRNA base methylation	4/1616	11/18670	0.01124	0.2161	0.2005	FDXACB1/TRMT112/NSUN5P2/METTL16	4
BP	GO:1900112	regulation of histone H3-K9 trimethylation	4/1616	11/18670	0.01124	0.2161	0.2005	SMARCB1/ZNF274/MECP2/SIRT1	4
BP	GO:1905146	lysosomal protein catabolic process	4/1616	11/18670	0.01124	0.2161	0.2005	GBA/TMEM199/MGAT3/ATP13A2	4
BP	GO:0030260	entry into host cell	20/1616	134/18670	0.01134	0.2161	0.2005	SLC20A2/IFITM2/HYAL3/CXCR4/SLC52A2/SLC1A5/SIVA1/VPS18/CDHR3/HSPA1A/TRIM11/DYNLT1/IFITM1/IFITM3/LGALS9/CD46/CTNND1/SELPLG/HAVCR1/ZNF639	20
BP	GO:0044409	entry into host	20/1616	134/18670	0.01134	0.2161	0.2005	SLC20A2/IFITM2/HYAL3/CXCR4/SLC52A2/SLC1A5/SIVA1/VPS18/CDHR3/HSPA1A/TRIM11/DYNLT1/IFITM1/IFITM3/LGALS9/CD46/CTNND1/SELPLG/HAVCR1/ZNF639	20
BP	GO:0051806	entry into cell of other organism involved in symbiotic interaction	20/1616	134/18670	0.01134	0.2161	0.2005	SLC20A2/IFITM2/HYAL3/CXCR4/SLC52A2/SLC1A5/SIVA1/VPS18/CDHR3/HSPA1A/TRIM11/DYNLT1/IFITM1/IFITM3/LGALS9/CD46/CTNND1/SELPLG/HAVCR1/ZNF639	20
BP	GO:0051828	entry into other organism involved in symbiotic interaction	20/1616	134/18670	0.01134	0.2161	0.2005	SLC20A2/IFITM2/HYAL3/CXCR4/SLC52A2/SLC1A5/SIVA1/VPS18/CDHR3/HSPA1A/TRIM11/DYNLT1/IFITM1/IFITM3/LGALS9/CD46/CTNND1/SELPLG/HAVCR1/ZNF639	20
BP	GO:0061077	chaperone-mediated protein folding	11/1616	59/18670	0.01147	0.2164	0.2007	DNAJB5/PDCD5/DFFA/FKBP4/HSPA1A/DNAJB1/SGTB/UNC45A/HSPA1L/TOR2A/HSPA13	11
BP	GO:0070527	platelet aggregation	11/1616	59/18670	0.01147	0.2164	0.2007	PTPN6/ACTG1/CEACAM1/ACTB/P2RY12/SH2B3/BLOC1S4/FERMT3/MYL12A/TSPAN32/FIBP	11
BP	GO:0043902	positive regulation of multi-organism process	26/1616	188/18670	0.01154	0.2164	0.2007	CCNT1/TBC1D20/NOTCH1/TAF11/HYAL3/SMARCB1/POLR2D/IFIT1/TRAF6/ANKRD17/VPS37B/GRN/PLCB1/POLR2H/ACVR1B/PKN2/TRIM11/HDAC2/DDB1/ZCCHC3/TSG101/LGALS9/RSF1/CFL1/EP300/ZNF639	26
BP	GO:0048193	Golgi vesicle transport	45/1616	368/18670	0.01155	0.2164	0.2007	CUX1/PDCD6/USO1/TEX261/TBC1D20/GOLPH3L/YIF1A/LMAN2L/DCTN4/CEP19/CSK/WHAMMP3/INSIG1/KIF22/SAR1A/TRIM23/WHAMM/SNAP23/SYS1/GOSR1/TRAPPC6A/EXOC8/DNM2/RAB30/CSNK1D/GORASP1/CAPZB/CCDC22/MPPE1/RANGRF/ACSL3/COG4/ATP9B/DYNC1LI2/EXOC6B/VCP/DYNLL1/PRKCI/TMEM115/RAB10/RAB1B/HTT/GOLGA3/CYTH3/KIF13A	45
BP	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	13/1616	75/18670	0.01162	0.2164	0.2007	IKBKB/SNAP23/PSME2/PSMD5/TAP1/PSMA5/PSMA2/HLA-H/PSME4/HLA-A/PSMB3/HLA-C/PSMD2	13
BP	GO:0010499	proteasomal ubiquitin-independent protein catabolic process	6/1616	23/18670	0.01162	0.2164	0.2007	NFE2L2/ENC1/PSMA5/PSMA2/PSME4/PSMB3	6
BP	GO:0043576	regulation of respiratory gaseous exchange	6/1616	23/18670	0.01162	0.2164	0.2007	SLC5A3/NR4A2/NLGN3/FTO/MECP2/PASK	6
BP	GO:0046365	monosaccharide catabolic process	12/1616	67/18670	0.01166	0.2164	0.2007	HK1/XYLB/TKTL1/SORD/FUT4/GALK2/GALK1/GALT/HK2/PFKL/FOXK2/PFKP	12
BP	GO:1901222	regulation of NIK/NF-kappaB signaling	18/1616	117/18670	0.01172	0.2169	0.2011	NFKBIA/PPM1B/TNFRSF10B/TERF2IP/ZC3H12A/TRAF6/MAP3K7/NR3C2/CD27/RASSF2/C1QTNF3/RBCK1/LGALS9/EP300/ZFP91/RC3H2/PPM1A/TRAF4	18
BP	GO:1901028	regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	9/1616	44/18670	0.01179	0.2175	0.2017	NMT1/HIP1R/MUL1/GSK3A/HSPA1A/BID/YWHAZ/TFDP2/TP63	9
BP	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion	8/1616	37/18670	0.01233	0.2228	0.2066	POLD2/GTF2H5/ERCC2/POLD4/RPA2/DDB1/GTF2H4/RPA1	8
BP	GO:0051084	'de novo' posttranslational protein folding	8/1616	37/18670	0.01233	0.2228	0.2066	DNAJB5/CHCHD4/HSPA1A/DNAJB1/HSPA1L/TOR2A/HSPA13/ENTPD5	8
BP	GO:0001675	acrosome assembly	5/1616	17/18670	0.01235	0.2228	0.2066	TBC1D20/TBPL1/RFX2/CCDC136/ACRBP	5
BP	GO:0043923	positive regulation by host of viral transcription	5/1616	17/18670	0.01235	0.2228	0.2066	CCNT1/TAF11/SMARCB1/EP300/ZNF639	5
BP	GO:0070131	positive regulation of mitochondrial translation	5/1616	17/18670	0.01235	0.2228	0.2066	COA3/NSUN4/RPUSD3/TRMT10C/CDK5RAP1	5
BP	GO:0070525	tRNA threonylcarbamoyladenosine metabolic process	5/1616	17/18670	0.01235	0.2228	0.2066	TRMT10C/PUS1/OSGEP/TRMT5/CDK5RAP1	5
BP	GO:0071360	cellular response to exogenous dsRNA	5/1616	17/18670	0.01235	0.2228	0.2066	IFIT1/MUL1/ZCCHC3/PQBP1/DDX58	5
BP	GO:0000305	response to oxygen radical	7/1616	30/18670	0.01241	0.2228	0.2066	NFE2L2/GCH1/PARK7/DHFR/NOS3/FANCC/FBLN5	7
BP	GO:1901796	regulation of signal transduction by p53 class mediator	25/1616	180/18670	0.01242	0.2228	0.2066	EHMT2/CDK5/TAF11/CHEK2/JMY/PRKAB1/PRKAG2/ING5/MAPK11/TWIST1/RPA2/HDAC2/BRPF1/RMI2/ATAD5/RRN3/TAF15/EP300/PHF20/NUAK1/TAF13/TP63/RPA1/SIRT1/ATRIP	25
BP	GO:0016241	regulation of macroautophagy	24/1616	171/18670	0.01249	0.2231	0.2069	PIM2/CDK5/PHF23/PRKAB1/SH3GLB1/MAP3K7/PIK3CA/PRKAG2/EXOC8/SMCR8/GBA/SMURF1/BNIP3/ATP6V1G1/IRGM/SLC38A9/ATP6V0E1/TSC1/RAB1B/HTT/SPTLC2/ATP13A2/LAMTOR2/SIRT1	24
BP	GO:0030833	regulation of actin filament polymerization	23/1616	162/18670	0.01252	0.2231	0.2069	PYCARD/JMY/HIP1R/WHAMMP3/WHAMM/ARPC1B/HAX1/GMFB/RICTOR/SPIRE2/TWF2/VASP/CAPZB/CORO1B/PRKCE/TWF1/TMSB4Y/CORO1A/FCHSD1/WASL/FMN1/NCKAP1/ARPC5	23
BP	GO:0006301	postreplication repair	10/1616	52/18670	0.01259	0.2231	0.2069	PARP10/POLD2/ZBTB1/ISG15/POLD4/SPRTN/RPA2/VCP/WDR33/RPA1	10
BP	GO:0051258	protein polymerization	36/1616	283/18670	0.01259	0.2231	0.2069	CAMSAP3/PYCARD/JMY/HIP1R/WHAMMP3/WHAMM/ARPC1B/CENPJ/TPPP3/HAX1/FKBP4/GMFB/RICTOR/CDKN1B/SPIRE2/HSPA1A/CSNK1D/TWF2/VTN/VASP/CAPZB/CORO1B/PRKCE/RANGRF/PSTPIP2/TWF1/TMSB4Y/CORO1A/MECP2/NDE1/FCHSD1/WASL/TUBGCP5/FMN1/NCKAP1/ARPC5	36
BP	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	14/1616	84/18670	0.01266	0.2236	0.2073	THBS1/RPS6KA1/PRDX3/PRDX5/CD27/PARK7/SIAH2/KLF4/CDKN2D/HERPUD1/GPX1/FNIP1/ADORA2A/RAF1	14
BP	GO:0034612	response to tumor necrosis factor	39/1616	312/18670	0.01275	0.2246	0.2083	ENDOG/SPATA2/GBP1/TNFRSF6B/NFKBIA/IKBKB/HYAL3/ZC3H12A/PYCARD/TNFAIP3/NFE2L2/THBS1/MAP3K14/PSME2/GCH1/RORA/CD27/GBA/HSPA1A/TXNDC17/PSMD5/RBCK1/SMPD4/ZFP36L1/PSMA5/CEBPA/ADAM9/PSMA2/ZFP36L2/NR1D1/PSME4/COL1A1/CXCL16/ASS1/PSMB3/KRT8/APOA1/PSMD2/SIRT1	39
BP	GO:0000422	autophagy of mitochondrion	13/1616	76/18670	0.01294	0.2259	0.2095	MUL1/HAX1/GSK3A/PARK7/GBA/SMURF1/BNIP3/ATG14/ATG2A/CTSK/HK2/HTT/ATP13A2	13
BP	GO:0061726	mitochondrion disassembly	13/1616	76/18670	0.01294	0.2259	0.2095	MUL1/HAX1/GSK3A/PARK7/GBA/SMURF1/BNIP3/ATG14/ATG2A/CTSK/HK2/HTT/ATP13A2	13
BP	GO:0006260	DNA replication	35/1616	274/18670	0.01294	0.2259	0.2095	CHTF8/STAG2/SDE2/EHMT2/NASP/POLD2/POLL/ORC6/RNASEH1/CHEK2/POLD4/ZNF830/DBF4/PRIM1/ANKRD17/POLB/RBM14/ING5/KAT7/TSPYL2/RPA2/ETAA1/RMI2/AICDA/ATAD5/SENP2/NFIC/CCDC88A/DDX11/UPF1/BCL6/RPA1/MCM9/NFIA/ATRIP	35
BP	GO:0045727	positive regulation of translation	19/1616	127/18670	0.01304	0.2269	0.2104	CDK4/POLR2D/MIF4GD/PCIF1/COA3/THBS1/NSUN4/RPUSD3/TRMT10C/ELAVL1/RBM3/RPS6KB2/YTHDF3/LARP4/KRT17/EIF2AK4/USP16/CDK5RAP1/PASK	19
BP	GO:0032092	positive regulation of protein binding	15/1616	93/18670	0.01349	0.234	0.217	CDK5/MEN1/SPPL3/HIP1R/DTX3L/TRIB3/TCF7L2/PARK7/BMP4/VTN/RAPGEF2/EP300/MFNG/CTHRC1/TRAF4	15
BP	GO:0051701	interaction with host	28/1616	209/18670	0.01357	0.2347	0.2177	SLC20A2/IFITM2/HYAL3/ZC3H12A/CXCR4/IFIT1/SLC52A2/KPNA5/VPS37B/SLC1A5/SIVA1/VPS18/CDHR3/HSPA1A/TRIM11/BCL2L1/DYNLT1/DDB1/IFITM1/TSG101/IFITM3/LGALS9/CD46/CTNND1/EIF2AK4/SELPLG/HAVCR1/ZNF639	28
BP	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	9/1616	45/18670	0.01363	0.235	0.218	CHEK2/PYCARD/TOPORS/SHISA5/ATAD5/EP300/TP63/CDKN1A/SIRT1	9
BP	GO:1903901	negative regulation of viral life cycle	14/1616	85/18670	0.01398	0.2404	0.2229	IFITM2/PARP10/ISG15/ZC3H12A/IFIT1/RSAD2/TRIM11/BST2/AICDA/IFITM1/IFITM3/EIF2AK4/OAS1/ISG20	14
BP	GO:0016236	macroautophagy	37/1616	295/18670	0.01424	0.2408	0.2233	PIM2/CDK5/PHF23/PRKAB1/VPS37B/SH3GLB1/MAP3K7/PIK3CA/PRKAG2/ATG16L1/EXOC8/TEX264/SMCR8/MTMR14/GBA/WDR81/EMC6/SMURF1/BNIP3/ATG14/SNAPIN/TSG101/ATG2A/ATP6V1G1/IRGM/SLC38A9/ATP6V0E1/VCP/TSC1/DYNLL1/RAB1B/HTT/YOD1/SPTLC2/ATP13A2/LAMTOR2/SIRT1	37
BP	GO:0038066	p38MAPK cascade	10/1616	53/18670	0.01435	0.2408	0.2233	PER1/PRMT1/ZC3H12A/DUSP1/MAP3K3/RELL1/ZFP36L1/GADD45A/LGALS9/PHLPP1	10
BP	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	13/1616	77/18670	0.01437	0.2408	0.2233	EDC3/DCP1A/POLR2D/DDX6/TNRC6B/EXOSC5/BTG2/DIS3/ZFP36L1/DCP2/ZFP36L2/WDR61/CNOT6L	13
BP	GO:0016575	histone deacetylation	13/1616	77/18670	0.01437	0.2408	0.2233	PER1/AKAP8/PHB/CAMK2D/MIER1/SFPQ/MORF4L1/RBM14/HDAC2/AKAP8L/BAZ2A/BCL6/SIRT1	13
BP	GO:0031397	negative regulation of protein ubiquitination	13/1616	77/18670	0.01437	0.2408	0.2233	PARP10/CDK5/USP4/ISG15/TNFAIP3/DTX3L/PARK7/HSPA1A/SPOPL/SENP2/GLMN/PRKCE/DNAJA1	13
BP	GO:0008535	respiratory chain complex IV assembly	6/1616	24/18670	0.01439	0.2408	0.2233	COA5/COA3/SCO1/BCS1L/SCO2/COX19	6
BP	GO:0021904	dorsal/ventral neural tube patterning	6/1616	24/18670	0.01439	0.2408	0.2233	GORAB/BMP4/IFT122/GPR161/GSC/MKS1	6
BP	GO:0050687	negative regulation of defense response to virus	6/1616	24/18670	0.01439	0.2408	0.2233	PPM1B/MUL1/RNF26/GPATCH3/RNF125/MICB	6
BP	GO:2001236	regulation of extrinsic apoptotic signaling pathway	22/1616	155/18670	0.01441	0.2408	0.2233	FEM1B/TNFRSF10B/PYCARD/STRADB/TNFAIP3/THBS1/TCF7L2/TNFSF10/PARK7/SIAH2/BCL10/FADD/BMP4/HSPA1A/BID/NOS3/BCL2L1/RBCK1/FAIM2/GPX1/RAF1/HTT	22
BP	GO:0006778	porphyrin-containing compound metabolic process	8/1616	38/18670	0.01447	0.2408	0.2233	HMOX2/IREB2/SLC25A38/SRRD/RSAD1/IBA57/ALAD/SLC11A2	8
BP	GO:0015804	neutral amino acid transport	8/1616	38/18670	0.01447	0.2408	0.2233	SLC43A2/NFKBIE/SLC1A5/SLC3A1/SLC25A38/SLC7A9/SLC38A9/CTNS	8
BP	GO:0042733	embryonic digit morphogenesis	11/1616	61/18670	0.01463	0.2429	0.2253	NOTCH1/ROR2/FZD6/TMEM107/CREBBP/BMP4/TWIST1/HDAC2/IMPAD1/IFT122/MKS1	11
BP	GO:0043543	protein acylation	32/1616	248/18670	0.01477	0.2437	0.226	PER1/ZDHHC16/PPM1B/SMARCB1/TERF2IP/NMT1/CREBBP/MORF4L1/MAP3K7/ACTL6A/ING5/KAT7/PARK7/MBIP/ZDHHC9/TWIST1/KANSL2/HDAC2/GOLGA7B/BRPF1/RSF1/ATAT1/GTF3C4/EP300/PHF20/MECP2/BRD1/CDYL/PPM1A/TADA1/DLD/SIRT1	32
BP	GO:0046434	organophosphate catabolic process	32/1616	248/18670	0.01477	0.2437	0.226	NUP50/HK1/PGAM4/CNP/PRKAG2/NUDT9/NUP133/NUDT4/ASPDH/AAAS/NUP35/NAPEPLD/NUDT1/PLA2G15/SMPD4/PDE7A/PFKFB3/DCTPP1/GALK1/PGK2/HK2/GPX1/PFKL/VCP/SMUG1/FOXK2/ABHD6/PNP/PFKFB4/PFKP/NT5C1A/ENTPD5	32
BP	GO:0042158	lipoprotein biosynthetic process	15/1616	94/18670	0.01481	0.2437	0.226	ZDHHC16/PIGA/PPM1B/NMT1/ZDHHC9/GBA/GOLGA7B/PIGH/MPPE1/IRGM/PIGL/DPM1/PPM1A/APOA1/GPAA1	15
BP	GO:0042168	heme metabolic process	7/1616	31/18670	0.01486	0.2438	0.2261	HMOX2/IREB2/SLC25A38/SRRD/IBA57/ALAD/SLC11A2	7
BP	GO:0034248	regulation of cellular amide metabolic process	56/1616	483/18670	0.01499	0.2448	0.2271	PER1/CDK4/EIF1B/POLR2D/MIF4GD/ZC3H12A/ORMDL2/PCIF1/COA3/KBTBD8/NFE2L2/THBS1/PA2G4/TRNAU1AP/SAMD8/RPS6KA1/NSUN4/IREB2/TSFM/TNRC6B/EIF1/GSK3A/RPUSD3/PPP1R15B/CTSA/ENC1/DHFR/EIF4A2/METTL16/SEPSECS/TRMT10C/BTG2/ELAVL1/RBM4B/ZFP36L1/RBM4/AIRE/RBM3/FTO/RPS6KB2/ZFP36L2/ATF4/YTHDF3/PAIP2/LARP4/KRT17/TSC1/CNOT6L/EIF2AK4/UPF1/USP16/DPH3P1/ATP13A2/CDK5RAP1/PASK/DPH2	56
BP	GO:0002698	negative regulation of immune effector process	18/1616	120/18670	0.015	0.2448	0.2271	PTPN6/PPM1B/ZC3H12A/MUL1/CEACAM1/GRN/BST2/RNF26/GPATCH3/LGALS9/RNF125/MICA/MICB/RC3H2/JAK3/BCL6/SOCS5/APOA1	18
BP	GO:0043487	regulation of RNA stability	25/1616	183/18670	0.01509	0.2456	0.2277	DCP1A/ZC3H12A/SERBP1/PSME2/METTL16/TBRG4/HSPA1A/EXOSC5/ELAVL1/DIS3/PSMD5/ZFP36L1/PSMA5/DCP2/RBM38/FTO/PSMA2/YWHAZ/ZFP36L2/PSME4/YTHDF3/CNOT6L/UPF1/PSMB3/PSMD2	25
BP	GO:0031348	negative regulation of defense response	31/1616	239/18670	0.01514	0.2457	0.2279	PPM1B/ZC3H12A/PYCARD/MVK/SOCS3/TNFAIP3/NR1D2/MUL1/CEACAM1/GRN/RORA/ACP5/C1QTNF3/GBA/ASH1L/KLF4/RNF26/GPATCH3/LGALS9/METRNL/TRAFD1/RNF125/MICA/TNFAIP8L2/MICB/NR1D1/YTHDF3/GPX1/ADORA2A/SOCS5/APOA1	31
BP	GO:0006417	regulation of translation	50/1616	424/18670	0.01548	0.2505	0.2324	PER1/CDK4/EIF1B/POLR2D/MIF4GD/ZC3H12A/PCIF1/COA3/KBTBD8/THBS1/PA2G4/TRNAU1AP/RPS6KA1/NSUN4/IREB2/TSFM/TNRC6B/EIF1/RPUSD3/PPP1R15B/ENC1/DHFR/EIF4A2/METTL16/SEPSECS/TRMT10C/BTG2/ELAVL1/RBM4B/ZFP36L1/RBM4/AIRE/RBM3/FTO/RPS6KB2/ZFP36L2/ATF4/YTHDF3/PAIP2/LARP4/KRT17/TSC1/CNOT6L/EIF2AK4/UPF1/USP16/DPH3P1/CDK5RAP1/PASK/DPH2	50
BP	GO:0050852	T cell receptor signaling pathway	27/1616	202/18670	0.01557	0.2513	0.2331	PTPN6/GBP1/IKBKB/LAT/ZC3H12A/TRAF6/KCNN4/CSK/SPPL3/PIK3R1/MAP3K7/CEACAM1/PIK3CA/PSME2/BTN2A1/BCL10/ELF1/PSMD5/RBCK1/PSMA5/PSMA2/UBASH3A/PSME4/BTN2A3P/RC3H2/PSMB3/PSMD2	27
BP	GO:0099640	axo-dendritic protein transport	4/1616	12/18670	0.01572	0.2517	0.2335	SFPQ/MAPK8IP3/RAB27B/MAP1A	4
BP	GO:0045333	cellular respiration	26/1616	193/18670	0.01584	0.2517	0.2335	NDUFS7/CISD1/LYRM7/ETFA/NDUFS2/PRELID1/NDUFA12/PDHA1/PIK3CA/IREB2/COQ10B/NDUFB8/PARK7/TBRG4/FASTKD5/BID/BNIP3/NDUFB11/NDUFB2/MECP2/ETFB/VCP/NDUFB10/COQ9/DLD/D2HGDH	26
BP	GO:0002098	tRNA wobble uridine modification	5/1616	18/18670	0.0159	0.2517	0.2335	ELP5/TRMU/ALKBH8/DPH3P1/CTU1	5
BP	GO:0007250	activation of NF-kappaB-inducing kinase activity	5/1616	18/18670	0.0159	0.2517	0.2335	TNFRSF10B/TRAF6/MAP3K7/ZFP91/TRAF4	5
BP	GO:0043555	regulation of translation in response to stress	5/1616	18/18670	0.0159	0.2517	0.2335	RPS6KA1/PPP1R15B/RBM4/ATF4/EIF2AK4	5
BP	GO:0070233	negative regulation of T cell apoptotic process	5/1616	18/18670	0.0159	0.2517	0.2335	CD27/FADD/BMP4/TSC22D3/JAK3	5
BP	GO:0097094	craniofacial suture morphogenesis	5/1616	18/18670	0.0159	0.2517	0.2335	FOXN3/INSIG1/BMP4/TWIST1/MMP14	5
BP	GO:0051651	maintenance of location in cell	15/1616	95/18670	0.01622	0.2557	0.2372	HK1/CDK5/TOPORS/INSIG1/ATP2A1/SRI/PARK7/TWF2/TWF1/TMSB4Y/HK2/SPAG4/ANKRD13C/GPSM2/GPAA1	15
BP	GO:0043618	regulation of transcription from RNA polymerase II promoter in response to stress	18/1616	121/18670	0.01624	0.2557	0.2372	EGLN2/HIF1AN/NOTCH1/EGLN3/NFE2L2/CREBBP/PSME2/HSPA1A/PSMD5/DNAJB1/PSMA5/PSMA2/EP300/ATF4/PSME4/PSMB3/CHD6/PSMD2	18
BP	GO:0002260	lymphocyte homeostasis	11/1616	62/18670	0.01644	0.2574	0.2387	SIT1/LAT/TNFAIP3/BCL10/FADD/TSC22D3/SOS1/LGALS9/CORO1A/RC3H2/JAK3	11
BP	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	11/1616	62/18670	0.01644	0.2574	0.2387	SERINC3/TNFRSF10B/TRIB3/TMEM117/ATP2A1/PARK7/HSPA1A/BCL2L1/HERPUD1/ATF4/SIRT1	11
BP	GO:0016571	histone methylation	20/1616	139/18670	0.01657	0.2587	0.2399	PRMT1/EHMT2/PHF1/CARM1/SMARCB1/MEN1/PRDM4/PAGR1/PRMT2/NTMT1/ASH1L/ZNF274/JARID2/BRD4/MECP2/SETD1B/WDR61/TET1/GFI1/SIRT1	20
BP	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	16/1616	104/18670	0.01683	0.2604	0.2415	MOAP1/CHEK2/PYCARD/TOPORS/CASP9/POLB/SHISA5/PIK3R1/BID/BCL2L1/CDKN2D/ATAD5/EP300/TP63/CDKN1A/SIRT1	16
BP	GO:0033683	nucleotide-excision repair, DNA incision	8/1616	39/18670	0.01686	0.2604	0.2415	POLD2/GTF2H5/ERCC2/POLD4/RPA2/DDB1/GTF2H4/RPA1	8
BP	GO:0042769	DNA damage response, detection of DNA damage	8/1616	39/18670	0.01686	0.2604	0.2415	POLD2/MRPS26/WDR48/POLD4/RPA2/DDB1/DNAJA1/RPA1	8
BP	GO:0072595	maintenance of protein localization in organelle	8/1616	39/18670	0.01686	0.2604	0.2415	HK1/CDK5/TOPORS/INSIG1/PARK7/HK2/ANKRD13C/GPAA1	8
BP	GO:0070129	regulation of mitochondrial translation	6/1616	25/18670	0.01758	0.2708	0.2511	COA3/NSUN4/TSFM/RPUSD3/TRMT10C/CDK5RAP1	6
BP	GO:1902807	negative regulation of cell cycle G1/S phase transition	19/1616	131/18670	0.01774	0.2722	0.2524	CDK4/PRMT1/CARM1/CDK2AP2/CHEK2/MEN1/MYO16/CDKN2B/CDKN1B/PRMT2/BTG2/RPA2/KLF4/CDKN2D/GADD45A/EP300/TFDP2/CNOT6L/CDKN1A	19
BP	GO:1903900	regulation of viral life cycle	21/1616	149/18670	0.01779	0.2722	0.2524	IFITM2/PARP10/TBC1D20/NOTCH1/ISG15/ZC3H12A/IFIT1/RSAD2/VPS37B/PKN2/TRIM11/BST2/DDB1/AICDA/IFITM1/TSG101/IFITM3/LGALS9/EIF2AK4/OAS1/ISG20	21
BP	GO:1903364	positive regulation of cellular protein catabolic process	20/1616	140/18670	0.01781	0.2722	0.2524	SOCS4/TNFAIP3/NFE2L2/TRIB3/ZFAND2A/GSK3A/FBXO22/CSNK1E/GBA/HSPA1A/CSNK1D/SMURF1/TMTC3/CEBPA/CCDC22/USP5/HERPUD1/VCP/SOCS5/KCNE2	20
BP	GO:0072524	pyridine-containing compound metabolic process	26/1616	195/18670	0.01788	0.2725	0.2528	PSAT1/NUP50/PARP10/HK1/PGAM4/PDHA1/PRKAG2/TALDO1/NUP133/ASPDH/AAAS/NUP35/PFKFB3/GALK1/PGK2/HK2/PFKL/VCP/FOXK2/PNPO/PNP/PFKFB4/PFKP/DLD/MPC1/ENTPD5	26
BP	GO:2000107	negative regulation of leukocyte apoptotic process	9/1616	47/18670	0.01795	0.2729	0.2531	IRF7/CD27/BCL10/FADD/BMP4/TSC22D3/IRS2/JAK3/BCL6	9
BP	GO:0042440	pigment metabolic process	12/1616	71/18670	0.01811	0.2746	0.2547	GART/HMOX2/IREB2/SLC25A38/SRRD/RAPGEF2/IBA57/DDT/CTNS/MTHFD1L/ALAD/SLC11A2	12
BP	GO:0002821	positive regulation of adaptive immune response	16/1616	105/18670	0.01831	0.2748	0.2549	ZBTB1/PYCARD/TRAF6/RSAD2/MAP3K7/FADD/IL12A/ATAD5/CLCF1/IL27RA/HLA-H/HLA-A/EIF2AK4/HLA-C/SOCS5/SIRT1	16
BP	GO:0032006	regulation of TOR signaling	16/1616	105/18670	0.01831	0.2748	0.2549	PDCD6/SIK1/TTI1/PIK3CA/GSK3A/RICTOR/SMCR8/GBA/AKT1S1/HTR6/WDR24/SLC38A9/FNIP1/TSC1/LAMTOR2/SIRT1	16
BP	GO:0006120	mitochondrial electron transport, NADH to ubiquinone	10/1616	55/18670	0.0184	0.2748	0.2549	NDUFS7/NDUFS2/NDUFA12/NDUFB8/PARK7/NDUFB11/NDUFB2/NDUFB10/COQ9/DLD	10
BP	GO:0006893	Golgi to plasma membrane transport	11/1616	63/18670	0.01841	0.2748	0.2549	GOLPH3L/CSK/TRIM23/SYS1/EXOC8/DNM2/CCDC22/ACSL3/EXOC6B/RAB10/KIF13A	11
BP	GO:0031571	mitotic G1 DNA damage checkpoint	11/1616	63/18670	0.01841	0.2748	0.2549	PRMT1/CARM1/CHEK2/CDKN1B/BTG2/RPA2/GADD45A/EP300/TFDP2/CNOT6L/CDKN1A	11
BP	GO:0044819	mitotic G1/S transition checkpoint	11/1616	63/18670	0.01841	0.2748	0.2549	PRMT1/CARM1/CHEK2/CDKN1B/BTG2/RPA2/GADD45A/EP300/TFDP2/CNOT6L/CDKN1A	11
BP	GO:0006767	water-soluble vitamin metabolic process	14/1616	88/18670	0.01861	0.2771	0.257	PSAT1/MMACHC/MTHFS/RFK/SLC52A2/TKTL1/ACP5/DHFR/MTHFD2L/SLC2A1/SLC25A19/MTHFD1L/PNPO/CTRC	14
BP	GO:0001738	morphogenesis of a polarized epithelium	20/1616	141/18670	0.01912	0.2833	0.2627	ROR2/CAMSAP3/FZD6/WDR1/PSME2/AP2S1/SMURF1/PSMD5/PSMA5/ARHGEF19/PSMA2/PSME4/PSMB3/TP63/CTHRC1/RAB10/NPHP3/PSMD2/MKS1/SAPCD2	20
BP	GO:0009411	response to UV	20/1616	141/18670	0.01912	0.2833	0.2627	SDE2/ZBTB1/ERCC2/HYAL3/MEN1/CREBBP/CASP9/PIK3R1/SPRTN/MYC/CDKN2D/DDB1/IL12A/EP300/ATF4/GPX1/MFAP4/EIF2AK4/CDKN1A/SIRT1	20
BP	GO:0044773	mitotic DNA damage checkpoint	15/1616	97/18670	0.01936	0.2854	0.2647	PRMT1/FOXN3/CARM1/CHEK2/ZNF830/CDKN1B/BTG2/RPA2/GADD45A/STK33/EP300/TFDP2/CNOT6L/MUS81/CDKN1A	15
BP	GO:0036293	response to decreased oxygen levels	44/1616	370/18670	0.01936	0.2854	0.2647	EGLN2/ENDOG/HIF1AN/HMOX2/NOTCH1/SRF/EGLN3/ERCC2/NR4A2/AHCY/CXCR4/NFE2L2/CREBBP/THBS1/LOXL2/XRCC1/PSME2/RORA/MYC/CDKN1B/TWIST1/BNIP3/PSMD5/ZFP36L1/MMP14/PSMA5/SLC2A1/PRKCE/PSMA2/GATA6/EP300/HK2/ATF4/PSME4/MECP2/UCP2/TSC1/PSMB3/RAF1/ALAD/PSMD2/SIRT1/TGFBR2/SLC11A2	44
BP	GO:0002456	T cell mediated immunity	16/1616	106/18670	0.01989	0.2906	0.2695	ZBTB1/TRAF6/RSAD2/MAP3K7/CEACAM1/CTSH/FADD/IL18RAP/IL12A/AIRE/CD46/MICA/HLA-H/MICB/HLA-A/HLA-C	16
BP	GO:0051881	regulation of mitochondrial membrane potential	12/1616	72/18670	0.02007	0.2906	0.2695	PRELID1/MUL1/PRDX3/PARK7/SLC25A36/BID/BNIP3/BCL2L1/CTNS/VCP/BCO2/ADORA2A	12
BP	GO:0034312	diol biosynthetic process	5/1616	19/18670	0.02008	0.2906	0.2695	GCH1/DHFR/GBA/ASAH2B/SPTLC2	5
BP	GO:0034471	ncRNA 5'-end processing	5/1616	19/18670	0.02008	0.2906	0.2695	RPP14/ABT1/POP1/TRMT10C/RPP40	5
BP	GO:0043687	post-translational protein modification	43/1616	361/18670	0.02009	0.2906	0.2695	CISH/KLHL11/DCAF6/FEM1B/COPS7A/MEN1/DCAF16/FN3KRP/SOCS3/PNPLA2/KBTBD8/ASB1/APOL1/FBXW4/ASB2/SHISA5/PSME2/FSTL3/SOCS2/RABGGTB/FBXO22/FEM1C/KLHL21/BMP4/PSMD5/UBA3/DDB1/ANKRD9/PSMA5/CCDC22/RAB13/PSMA2/FBXL3/FBXO21/IRGM/PSME4/ASB13/SKP2/PSMB3/RAB1B/SOCS5/APOA1/PSMD2	43
BP	GO:0042176	regulation of protein catabolic process	45/1616	381/18670	0.02026	0.2906	0.2695	EGLN2/PHB/CHEK2/SOCS4/SCO1/TNFAIP3/NFE2L2/TRIB3/TLK2/WDR91/PSME2/ZFAND2A/GSK3A/CTSA/CYP51A1/PARK7/FBXO22/CDKN1B/CSNK1E/GBA/HSPA1A/CSNK1D/SMURF1/AGAP2/DDB1/TMTC3/CEBPA/CCDC22/GLMN/ADAM9/USP5/HERPUD1/MGAT3/GPX1/WNT10B/VCP/MAP1A/UBE3A/YOD1/SOCS5/TRIM39/ALAD/KCNE2/ATP13A2/PSMD2	45
BP	GO:0045089	positive regulation of innate immune response	45/1616	381/18670	0.02026	0.2906	0.2695	IRF7/NFKBIA/IKBKB/PYCARD/TLR5/TRAF6/MAPKAPK3/TNFAIP3/CREBBP/RSAD2/ANKRD17/SFPQ/UNC93B1/MAP3K7/PSME2/RBM14/VAV1/BCL10/FADD/HSPA1A/PSMD5/IL18RAP/PSMA5/ZCCHC3/IL12A/RAB11FIP2/OTUD4/GPATCH3/PRKCE/PSMA2/RNF125/MICA/MUCL1/IRGM/EP300/CTSK/MICB/NR1D1/PSME4/PQBP1/PSMB3/RAF1/DDX58/GFI1/PSMD2	45
BP	GO:0006497	protein lipidation	14/1616	89/18670	0.02038	0.2906	0.2695	ZDHHC16/PIGA/PPM1B/NMT1/ZDHHC9/GBA/GOLGA7B/PIGH/MPPE1/IRGM/PIGL/DPM1/PPM1A/GPAA1	14
BP	GO:0002711	positive regulation of T cell mediated immunity	9/1616	48/18670	0.02045	0.2906	0.2695	ZBTB1/TRAF6/RSAD2/MAP3K7/FADD/IL12A/HLA-H/HLA-A/HLA-C	9
BP	GO:0030865	cortical cytoskeleton organization	9/1616	48/18670	0.02045	0.2906	0.2695	CDK5/IKBKB/WDR1/TIGD5/PDCD6IP/RAB13/EPB41L2/WASL/NCKAP1	9
BP	GO:0090199	regulation of release of cytochrome c from mitochondria	9/1616	48/18670	0.02045	0.2906	0.2695	MOAP1/PRELID1/PYCARD/PDCD5/TNFSF10/BID/BNIP3/BCL2L1/GPX1	9
BP	GO:0001736	establishment of planar polarity	18/1616	124/18670	0.02045	0.2906	0.2695	ROR2/FZD6/WDR1/PSME2/AP2S1/SMURF1/PSMD5/PSMA5/ARHGEF19/PSMA2/PSME4/PSMB3/TP63/CTHRC1/NPHP3/PSMD2/MKS1/SAPCD2	18
BP	GO:0007164	establishment of tissue polarity	18/1616	124/18670	0.02045	0.2906	0.2695	ROR2/FZD6/WDR1/PSME2/AP2S1/SMURF1/PSMD5/PSMA5/ARHGEF19/PSMA2/PSME4/PSMB3/TP63/CTHRC1/NPHP3/PSMD2/MKS1/SAPCD2	18
BP	GO:0044783	G1 DNA damage checkpoint	11/1616	64/18670	0.02055	0.2906	0.2695	PRMT1/CARM1/CHEK2/CDKN1B/BTG2/RPA2/GADD45A/EP300/TFDP2/CNOT6L/CDKN1A	11
BP	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	10/1616	56/18670	0.02072	0.2906	0.2695	PRMT1/CARM1/CHEK2/CDKN1B/BTG2/GADD45A/EP300/TFDP2/CNOT6L/CDKN1A	10
BP	GO:0010591	regulation of lamellipodium assembly	7/1616	33/18670	0.02075	0.2906	0.2695	RAC2/DNM2/TWF2/CAPZB/TWF1/BIN3/NCKAP1	7
BP	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	7/1616	33/18670	0.02075	0.2906	0.2695	EDC3/DCP1A/DDX6/EXOSC5/DIS3/DCP2/WDR61	7
BP	GO:0070536	protein K63-linked deubiquitination	7/1616	33/18670	0.02075	0.2906	0.2695	SPATA2/ZRANB1/TNFAIP3/OTUD4/VCP/USP16/YOD1	7
BP	GO:0006733	oxidoreduction coenzyme metabolic process	27/1616	207/18670	0.02083	0.2906	0.2695	NUP50/PARP10/HK1/PGAM4/PDHA1/PRKAG2/TALDO1/NUP133/COQ10B/ASPDH/AAAS/NUP35/PFKFB3/GALK1/PGK2/HK2/PFKL/VCP/COQ7/FOXK2/COQ9/PPTC7/PFKFB4/PFKP/DLD/MPC1/ENTPD5	27
BP	GO:0048024	regulation of mRNA splicing, via spliceosome	15/1616	98/18670	0.02109	0.2906	0.2695	MBNL2/PTBP1/RBM25/WTAP/METTL16/RBM19/RBM4B/RBM4/ZC3H10/RBM3/SRSF10/HNRNPL/HNRNPA1/KHDRBS3/RBM17	15
BP	GO:0006012	galactose metabolic process	4/1616	13/18670	0.02118	0.2906	0.2695	SLC35A2/GALK2/GALK1/GALT	4
BP	GO:0006384	transcription initiation from RNA polymerase III promoter	4/1616	13/18670	0.02118	0.2906	0.2695	BRF2/BRF1/TBPL1/GTF3C4	4
BP	GO:0009635	response to herbicide	4/1616	13/18670	0.02118	0.2906	0.2695	ZC3H12A/HNRNPA1/DAXX/ALAD	4
BP	GO:0033623	regulation of integrin activation	4/1616	13/18670	0.02118	0.2906	0.2695	CXCL13/RASIP1/P2RY12/KIF14	4
BP	GO:0034969	histone arginine methylation	4/1616	13/18670	0.02118	0.2906	0.2695	PRMT1/CARM1/PRDM4/PRMT2	4
BP	GO:0061029	eyelid development in camera-type eye	4/1616	13/18670	0.02118	0.2906	0.2695	SRF/TWIST1/HDAC2/SOS1	4
BP	GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	4/1616	13/18670	0.02118	0.2906	0.2695	NFKBIA/TNFAIP3/HSPA1A/IRGM	4
BP	GO:0090646	mitochondrial tRNA processing	4/1616	13/18670	0.02118	0.2906	0.2695	TRMT10C/PUS1/TRMT5/CDK5RAP1	4
BP	GO:1904925	positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization	4/1616	13/18670	0.02118	0.2906	0.2695	MUL1/GBA/SMURF1/HK2	4
BP	GO:0002230	positive regulation of defense response to virus by host	6/1616	26/18670	0.02122	0.2906	0.2695	ZC3H12A/PYCARD/DTX3L/PQBP1/EIF2AK4/DDX58	6
BP	GO:0060541	respiratory system development	26/1616	198/18670	0.02132	0.2913	0.2701	NOTCH1/SRF/ATXN1L/ASCL1/FSTL3/CTSH/BMP4/FLT4/GNG8/NOS3/ESRP2/MMP14/CEBPA/DHCR7/ITGA3/THRA/GATA6/EP300/ASXL1/RC3H2/FGF9/KCNAB1/ASS1/HSD11B1/NPHP3/TGFBR2	26
BP	GO:0035967	cellular response to topologically incorrect protein	22/1616	161/18670	0.02156	0.2938	0.2725	YIF1A/NFE2L2/PIK3R1/BFAR/GSK3A/PPP1R15B/CREBRF/HSPA1A/DNAJB9/TSPYL2/SERP2/TATDN2/HERPUD1/EP300/ATF4/VCP/HSPA1L/DDX11/HSPA13/CTH/DAXX/YOD1	22
BP	GO:0030098	lymphocyte differentiation	42/1616	353/18670	0.02174	0.2955	0.2741	CD83/PTPN6/SRF/PATZ1/LRRC8A/ZBTB1/BATF/PRELID1/ZC3H12A/RSAD2/CD79B/PIK3R1/IRF2BP2/RORA/CD27/VAV1/FADD/BMP4/DNAJB9/ZFP36L1/MMP14/IL12A/AIRE/AICDA/SOS1/LGALS9/CLCF1/CD46/ZFP36L2/EP300/MFNG/NHEJ1/RC3H2/JAK3/FNIP1/IFNA10/TSC1/BCL6/PNP/SOCS5/ITM2A/TGFBR2	42
BP	GO:0048002	antigen processing and presentation of peptide antigen	25/1616	189/18670	0.02178	0.2955	0.2741	MR1/IKBKB/DCTN4/ERAP2/PYCARD/TRAF6/KIF22/SNAP23/PSME2/AP2S1/DNM2/PSMD5/TAP1/CAPZB/PSMA5/IFI30/PSMA2/HLA-H/PSME4/DYNC1LI2/HLA-A/PSMB3/DYNLL1/HLA-C/PSMD2	25
BP	GO:0031929	TOR signaling	18/1616	125/18670	0.02203	0.2962	0.2747	PDCD6/SIK1/TTI1/PIK3CA/GSK3A/RICTOR/SMCR8/GBA/AKT1S1/HTR6/RPS6KB2/WDR24/CCDC88A/SLC38A9/FNIP1/TSC1/LAMTOR2/SIRT1	18
BP	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	18/1616	125/18670	0.02203	0.2962	0.2747	CDK4/PRMT1/CARM1/CDK2AP2/CHEK2/MYO16/CDKN2B/CDKN1B/PRMT2/BTG2/RPA2/KLF4/CDKN2D/GADD45A/EP300/TFDP2/CNOT6L/CDKN1A	18
BP	GO:0016054	organic acid catabolic process	34/1616	275/18670	0.02204	0.2962	0.2747	CPT1B/HMGCL/NAGK/ADO/CPT1C/ETFA/HYAL3/XYLB/ALDH8A1/MTHFS/AHCY/AMDHD1/BCAT1/DDAH2/GNPDA1/SORD/SLC27A4/GCAT/TWIST1/CYP4F12/PECR/NOS3/ALDH4A1/PLA2G15/BCKDK/NUDT19/IRS2/FAH/ETFB/HGD/LIPE/CTH/DLD/MCAT	34
BP	GO:0046395	carboxylic acid catabolic process	34/1616	275/18670	0.02204	0.2962	0.2747	CPT1B/HMGCL/NAGK/ADO/CPT1C/ETFA/HYAL3/XYLB/ALDH8A1/MTHFS/AHCY/AMDHD1/BCAT1/DDAH2/GNPDA1/SORD/SLC27A4/GCAT/TWIST1/CYP4F12/PECR/NOS3/ALDH4A1/PLA2G15/BCKDK/NUDT19/IRS2/FAH/ETFB/HGD/LIPE/CTH/DLD/MCAT	34
BP	GO:0015980	energy derivation by oxidation of organic compounds	35/1616	285/18670	0.02235	0.2985	0.2768	NDUFS7/CISD1/LYRM7/ETFA/NDUFS2/PRELID1/PPP1R3D/NDUFA12/PDHA1/PIK3CA/PRKAG2/IREB2/MYC/GSK3A/COQ10B/NDUFB8/GFPT2/PARK7/TBRG4/FASTKD5/BID/BNIP3/GBE1/NDUFB11/NDUFB2/NR1D1/MECP2/IRS2/ETFB/VCP/NDUFB10/COQ9/DLD/D2HGDH/PASK	35
BP	GO:0006458	'de novo' protein folding	8/1616	41/18670	0.02247	0.2985	0.2768	DNAJB5/CHCHD4/HSPA1A/DNAJB1/HSPA1L/TOR2A/HSPA13/ENTPD5	8
BP	GO:0044743	protein transmembrane import into intracellular organelle	8/1616	41/18670	0.02247	0.2985	0.2768	PEX12/GRPEL1/CHCHD4/PEX6/TOMM20L/PEX16/TIMM13/TIMM10	8
BP	GO:0050434	positive regulation of viral transcription	8/1616	41/18670	0.02247	0.2985	0.2768	CCNT1/TAF11/SMARCB1/POLR2D/POLR2H/RSF1/EP300/ZNF639	8
BP	GO:0050873	brown fat cell differentiation	8/1616	41/18670	0.02247	0.2985	0.2768	NAPEPLD/BNIP3/LRG1/CEBPA/METRNL/FTO/ADRB1/SIRT1	8
BP	GO:0017038	protein import	26/1616	199/18670	0.02257	0.2985	0.2769	NUP50/PEX12/NFKBIA/GRPEL1/IPO13/TMCO6/ZC3H12A/PDCD5/CHCHD4/KPNA5/PEX6/TOMM20L/PIK3R1/NUP133/PEX16/FAM53C/BMP4/NUP35/TIMM13/RANBP6/CBLB/RGPD6/FGF9/TIMM10/CSE1L/CDKN1A	26
BP	GO:0035966	response to topologically incorrect protein	26/1616	199/18670	0.02257	0.2985	0.2769	YIF1A/DNAJB5/NFE2L2/THBS1/PIK3R1/BFAR/GSK3A/PPP1R15B/CREBRF/HSPA1A/DNAJB9/TSPYL2/SERP2/DNAJB1/TATDN2/HERPUD1/EP300/ATF4/VCP/DNAJA1/HSPA1L/DDX11/HSPA13/CTH/DAXX/YOD1	26
BP	GO:0042110	T cell activation	53/1616	464/18670	0.0227	0.2995	0.2778	CD83/PTPN6/RAC2/SIT1/SRF/PATZ1/ZBTB1/YES1/BATF/PRELID1/LAT/ZC3H12A/PYCARD/TRAF6/CSK/CCND3/TREML2/RSAD2/PIK3R1/CEACAM1/PIK3CA/RORA/CD27/VAV1/BCL10/FADD/BMP4/ZFP36L1/IL12A/AIRE/SOS1/LGALS9/GLMN/CD46/MICA/CD7/ZFP36L2/TNFAIP8L2/MICB/CORO1A/NHEJ1/RC3H2/GNRH1/JAK3/IFNA10/TSC1/EIF2AK4/ADORA2A/BCL6/PNP/BTLA/SOCS5/TGFBR2	53
BP	GO:0048525	negative regulation of viral process	15/1616	99/18670	0.02293	0.3016	0.2798	IFITM2/PARP10/ISG15/ZC3H12A/IFIT1/RSAD2/TRIM11/BST2/AICDA/IFITM1/IFITM3/EIF2AK4/OAS1/ISG20/ZNF639	15
BP	GO:0001913	T cell mediated cytotoxicity	9/1616	49/18670	0.02319	0.3016	0.2798	CEACAM1/CTSH/FADD/IL12A/MICA/HLA-H/MICB/HLA-A/HLA-C	9
BP	GO:0019320	hexose catabolic process	10/1616	57/18670	0.02324	0.3016	0.2798	HK1/TKTL1/FUT4/GALK2/GALK1/GALT/HK2/PFKL/FOXK2/PFKP	10
BP	GO:0072431	signal transduction involved in mitotic G1 DNA damage checkpoint	10/1616	57/18670	0.02324	0.3016	0.2798	PRMT1/CARM1/CHEK2/CDKN1B/BTG2/GADD45A/EP300/TFDP2/CNOT6L/CDKN1A	10
BP	GO:1902400	intracellular signal transduction involved in G1 DNA damage checkpoint	10/1616	57/18670	0.02324	0.3016	0.2798	PRMT1/CARM1/CHEK2/CDKN1B/BTG2/GADD45A/EP300/TFDP2/CNOT6L/CDKN1A	10
BP	GO:0006261	DNA-dependent DNA replication	21/1616	153/18670	0.02328	0.3016	0.2798	CHTF8/STAG2/POLD2/ORC6/RNASEH1/CHEK2/POLD4/ZNF830/DBF4/PRIM1/POLB/RPA2/ETAA1/AICDA/ATAD5/SENP2/DDX11/UPF1/BCL6/RPA1/MCM9	21
BP	GO:0030168	platelet activation	21/1616	153/18670	0.02328	0.3016	0.2798	PTPN6/SRF/ACTG1/FZD6/PIK3R1/CEACAM1/PIK3CA/VAV1/ACTB/P2RY12/NOS3/SH2B3/PRKCE/BLOC1S4/YWHAZ/FERMT3/COL1A1/MYL12A/RAF1/TSPAN32/FIBP	21
BP	GO:0034250	positive regulation of cellular amide metabolic process	21/1616	153/18670	0.02328	0.3016	0.2798	CDK4/POLR2D/MIF4GD/PCIF1/COA3/NFE2L2/THBS1/NSUN4/GSK3A/RPUSD3/TRMT10C/ELAVL1/RBM3/RPS6KB2/YTHDF3/LARP4/KRT17/EIF2AK4/USP16/CDK5RAP1/PASK	21
BP	GO:0097581	lamellipodium organization	13/1616	82/18670	0.02342	0.3028	0.2809	ABI1/RAC2/WHAMM/DNM2/P2RY12/TWF2/CAPZB/CORO1B/TWF1/CCDC88A/BIN3/NCKAP1/ARPC5	13
BP	GO:0032543	mitochondrial translation	19/1616	135/18670	0.02365	0.304	0.282	MRPS5/MRPS18C/MRPS26/MTRF1L/COA3/MRPL51/NSUN4/TSFM/RPUSD3/TRMT10C/MRPL54/MRPL15/DARS2/MRPL44/ERAL1/WARS2/MRPS21/MRPL24/CDK5RAP1	19
BP	GO:1903322	positive regulation of protein modification by small protein conjugation or removal	19/1616	135/18670	0.02365	0.304	0.282	PDCD6/PHF23/WDR48/ZC3H12A/TOPORS/TRAF6/MUL1/TRIB3/SPRTN/NDFIP2/GSK3A/BCL10/MASTL/GORASP1/SENP2/ARRDC4/VCP/SKP2/UBE3A	19
BP	GO:0046031	ADP metabolic process	18/1616	126/18670	0.02369	0.304	0.282	NUP50/HK1/PGAM4/PRKAG2/NUDT9/NUP133/AAAS/NUP35/PFKFB3/GALK1/PGK2/HK2/PFKL/FOXK2/PFKFB4/PFKP/ENTPD5/AK3	18
BP	GO:0032102	negative regulation of response to external stimulus	43/1616	365/18670	0.02372	0.304	0.282	NOTCH1/CXCL13/PPM1B/RTN4RL1/SEMA4C/ZC3H12A/PYCARD/MVK/SOCS3/TNFAIP3/NR1D2/THBS1/MUL1/DUSP1/CEACAM1/GRN/SEMA4F/RORA/ACP5/C1QTNF3/CDKN1B/GBA/ASH1L/NOS3/KLF4/VTN/CORO1B/SH2B3/RNF26/F11/GPATCH3/METRNL/RNF125/TNFAIP8L2/MICB/NR1D1/DDT/GPX1/ADORA2A/SOCS5/C5/APOA1/CDKN1A	43
BP	GO:0030324	lung development	23/1616	172/18670	0.02405	0.3075	0.2852	NOTCH1/SRF/ATXN1L/ASCL1/FSTL3/CTSH/BMP4/FLT4/NOS3/ESRP2/MMP14/CEBPA/DHCR7/ITGA3/THRA/GATA6/EP300/ASXL1/RC3H2/FGF9/HSD11B1/NPHP3/TGFBR2	23
BP	GO:0009452	7-methylguanosine RNA capping	7/1616	34/18670	0.02424	0.3077	0.2854	GTF2H5/ERCC2/POLR2D/POLR2H/MNAT1/GTF2H4/TGS1	7
BP	GO:0017004	cytochrome complex assembly	7/1616	34/18670	0.02424	0.3077	0.2854	COA5/LYRM7/COA3/SCO1/BCS1L/SCO2/COX19	7
BP	GO:0036260	RNA capping	7/1616	34/18670	0.02424	0.3077	0.2854	GTF2H5/ERCC2/POLR2D/POLR2H/MNAT1/GTF2H4/TGS1	7
BP	GO:1901991	negative regulation of mitotic cell cycle phase transition	31/1616	248/18670	0.02427	0.3077	0.2854	CDK4/PRMT1/FOXN3/CARM1/CDK2AP2/CHEK2/ZNF830/DUSP1/MYO16/PSME2/CDKN2B/CDKN1B/PRMT2/BTG2/RPA2/KLF4/PSMD5/CDKN2D/ZFP36L1/PSMA5/GADD45A/PSMA2/ZFP36L2/EP300/PSME4/TFDP2/CNOT6L/PSMB3/GPR132/CDKN1A/PSMD2	31
BP	GO:0032507	maintenance of protein location in cell	12/1616	74/18670	0.02447	0.3095	0.2871	HK1/CDK5/TOPORS/INSIG1/PARK7/TWF2/TWF1/TMSB4Y/HK2/SPAG4/ANKRD13C/GPAA1	12
BP	GO:0090501	RNA phosphodiester bond hydrolysis	21/1616	154/18670	0.02483	0.3097	0.2872	ENDOG/RPP14/EDC3/TSEN15/ABT1/RNASEH1/ZC3H12A/POP1/DICER1/EXOSC5/DIS3/DCP2/MRPL44/NOL9/TOE1/RPP40/CNOT6L/TSN/REXO2/ISG20/UTP23	21
BP	GO:0070498	interleukin-1-mediated signaling pathway	15/1616	100/18670	0.0249	0.3097	0.2872	PELI2/NFKBIA/IKBKB/TRAF6/MAP3K7/MAP3K3/PSME2/PLCB1/PSMD5/PSMA5/OTUD4/PSMA2/PSME4/PSMB3/PSMD2	15
BP	GO:0030220	platelet formation	5/1616	20/18670	0.02491	0.3097	0.2872	PTPN6/SRF/CASP9/WDR1/EP300	5
BP	GO:0039529	RIG-I signaling pathway	5/1616	20/18670	0.02491	0.3097	0.2872	ANKRD17/ZCCHC3/GPATCH3/RNF125/DDX58	5
BP	GO:0043371	negative regulation of CD4-positive, alpha-beta T cell differentiation	5/1616	20/18670	0.02491	0.3097	0.2872	ZC3H12A/RC3H2/JAK3/BCL6/SOCS5	5
BP	GO:0046514	ceramide catabolic process	5/1616	20/18670	0.02491	0.3097	0.2872	NAGA/GBA/GALC/ASAH2B/GM2A	5
BP	GO:0050860	negative regulation of T cell receptor signaling pathway	5/1616	20/18670	0.02491	0.3097	0.2872	PTPN6/GBP1/CEACAM1/ELF1/UBASH3A	5
BP	GO:0098780	response to mitochondrial depolarisation	5/1616	20/18670	0.02491	0.3097	0.2872	MUL1/GBA/SMURF1/ATG14/HK2	5
BP	GO:0030041	actin filament polymerization	24/1616	182/18670	0.02502	0.3104	0.2878	PYCARD/JMY/HIP1R/WHAMMP3/WHAMM/ARPC1B/HAX1/GMFB/RICTOR/SPIRE2/TWF2/VASP/CAPZB/CORO1B/PRKCE/PSTPIP2/TWF1/TMSB4Y/CORO1A/FCHSD1/WASL/FMN1/NCKAP1/ARPC5	24
BP	GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	20/1616	145/18670	0.02513	0.311	0.2885	PTPN6/ZBTB1/ZC3H12A/TRAF6/TNFAIP3/RSAD2/MAP3K7/CEACAM1/FADD/IL12A/ATAD5/CLCF1/IL27RA/HLA-H/RC3H2/JAK3/HLA-A/BCL6/HLA-C/SOCS5	20
BP	GO:0032201	telomere maintenance via semi-conservative replication	6/1616	27/18670	0.02534	0.3123	0.2897	POLD2/POLD4/PRIM1/RPA2/UPF1/RPA1	6
BP	GO:0039528	cytoplasmic pattern recognition receptor signaling pathway in response to virus	6/1616	27/18670	0.02534	0.3123	0.2897	IRF7/ANKRD17/ZCCHC3/GPATCH3/RNF125/DDX58	6
BP	GO:0060218	hematopoietic stem cell differentiation	13/1616	83/18670	0.02565	0.3142	0.2914	SRF/ERCC2/BATF/NFE2L2/CHD2/PSME2/PSMD5/PSMA5/PSMA2/PSME4/PSMB3/MEOX1/PSMD2	13
BP	GO:0042149	cellular response to glucose starvation	8/1616	42/18670	0.02571	0.3142	0.2914	ZC3H12A/SIK1/NFE2L2/SH3GLB1/ATG14/SLC2A1/ATF4/HNRNPA1	8
BP	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	8/1616	42/18670	0.02571	0.3142	0.2914	ZC3H12A/EXOSC5/DIS3/DCP2/TOE1/CNOT6L/REXO2/ISG20	8
BP	GO:0018205	peptidyl-lysine modification	46/1616	397/18670	0.02576	0.3142	0.2914	PER1/NUP50/EHMT2/PHF1/SMARCB1/MEN1/TOPORS/CREBBP/MUL1/MORF4L1/LOXL2/MAP3K7/PAGR1/ACTL6A/NUP133/ING5/KAT7/PARK7/MBIP/AAAS/TWIST1/NUP35/ASH1L/KANSL2/HDAC2/BRPF1/SENP2/RSF1/ZNF274/JARID2/ATAT1/GTF3C4/EP300/BRD4/PHF20/SENP5/MECP2/BRD1/SETD1B/SUMO4/WDR61/TADA1/CTH/GFI1/SIRT5/SIRT1	46
BP	GO:0006403	RNA localization	29/1616	230/18670	0.02582	0.3142	0.2914	CCT5/HNRNPA1L2/NUP50/NOP10/POLR2D/MVP/TOMM20L/SFPQ/CCT6A/DDX19B/ENY2/NUP133/AAAS/NUP35/ZFP36L1/DCP2/G3BP2/SRSF11/TNKS/SENP2/SLU7/AKAP8L/SRRM1/SIDT1/HNRNPA1/TSC1/WDR33/UPF1/TGFBR2	29
BP	GO:2001234	negative regulation of apoptotic signaling pathway	29/1616	230/18670	0.02582	0.3142	0.2914	NR4A2/TNFRSF10B/PRELID1/STRADB/TNFAIP3/NFE2L2/THBS1/MNT/TCF7L2/TNFSF10/PARK7/SIAH2/FADD/BMP4/HSPA1A/BID/NOS3/BCL2L1/CDKN2D/ATAD5/HERPUD1/RRN3/FAIM2/GPX1/DNAJA1/RAF1/CTH/HTT/SIRT1	29
BP	GO:0002758	innate immune response-activating signal transduction	36/1616	298/18670	0.02593	0.3149	0.292	IRF7/NFKBIA/IKBKB/TLR5/TRAF6/MAPKAPK3/TNFAIP3/CREBBP/RSAD2/ANKRD17/UNC93B1/MAP3K7/PSME2/BCL10/FADD/HSPA1A/PSMD5/PSMA5/ZCCHC3/RAB11FIP2/OTUD4/GPATCH3/PRKCE/PSMA2/RNF125/MUCL1/IRGM/EP300/CTSK/NR1D1/PSME4/PSMB3/RAF1/DDX58/GFI1/PSMD2	36
BP	GO:0010718	positive regulation of epithelial to mesenchymal transition	9/1616	50/18670	0.02618	0.3166	0.2936	NOTCH1/LOXL2/TCF7L2/BMP4/TWIST1/HDAC2/COL1A1/ALX1/TGFBR2	9
BP	GO:0034656	nucleobase-containing small molecule catabolic process	9/1616	50/18670	0.02618	0.3166	0.2936	AHCY/NUDT9/GSK3A/NUDT1/AICDA/GALT/PNP/NT5C1A/ENTPD5	9
BP	GO:2000117	negative regulation of cysteine-type endopeptidase activity	14/1616	92/18670	0.02646	0.3194	0.2962	THBS1/RPS6KA1/PRDX3/PRDX5/CD27/PARK7/SIAH2/KLF4/CDKN2D/HERPUD1/GPX1/FNIP1/ADORA2A/RAF1	14
BP	GO:0097193	intrinsic apoptotic signaling pathway	35/1616	289/18670	0.02687	0.3237	0.3002	SERINC3/MOAP1/TNFRSF10B/CHEK2/PYCARD/JMY/TOPORS/NFE2L2/CASP9/POLB/SFPQ/TRIB3/SHISA5/PIK3R1/TMEM117/PDCD10/ATP2A1/PARK7/HSPA1A/BID/PLAGL2/BNIP3/BCL2L1/CDKN2D/ATAD5/HERPUD1/RRN3/EP300/ATF4/GPX1/DNAJA1/TP63/BCLAF1/CDKN1A/SIRT1	35
BP	GO:1903008	organelle disassembly	15/1616	101/18670	0.02699	0.3243	0.3008	MUL1/HAX1/GSK3A/PARK7/TEX264/GBA/SMURF1/BNIP3/ATG14/ATG2A/CTSK/HK2/VCP/HTT/ATP13A2	15
BP	GO:0006664	glycolipid metabolic process	16/1616	110/18670	0.02727	0.3257	0.302	ESYT2/PIGA/ST6GALNAC4/NAGA/ST3GAL5/ST3GAL2/CTSA/GBA/GALC/SMPD4/PIGH/GM2A/MPPE1/PIGL/DPM1/GPAA1	16
BP	GO:0090175	regulation of establishment of planar polarity	16/1616	110/18670	0.02727	0.3257	0.302	ROR2/FZD6/PSME2/AP2S1/SMURF1/PSMD5/PSMA5/ARHGEF19/PSMA2/PSME4/PSMB3/CTHRC1/NPHP3/PSMD2/MKS1/SAPCD2	16
BP	GO:0050657	nucleic acid transport	25/1616	193/18670	0.02739	0.3257	0.302	HNRNPA1L2/NUP50/POLR2D/MVP/TOMM20L/SFPQ/DDX19B/ENY2/NUP133/AAAS/NUP35/ZFP36L1/G3BP2/SRSF11/TNKS/SENP2/SLU7/AKAP8L/SRRM1/SIDT1/HNRNPA1/TSC1/WDR33/UPF1/TGFBR2	25
BP	GO:0050658	RNA transport	25/1616	193/18670	0.02739	0.3257	0.302	HNRNPA1L2/NUP50/POLR2D/MVP/TOMM20L/SFPQ/DDX19B/ENY2/NUP133/AAAS/NUP35/ZFP36L1/G3BP2/SRSF11/TNKS/SENP2/SLU7/AKAP8L/SRRM1/SIDT1/HNRNPA1/TSC1/WDR33/UPF1/TGFBR2	25
BP	GO:0006878	cellular copper ion homeostasis	4/1616	14/18670	0.02766	0.3257	0.302	SCO1/SCO2/CCDC22/COX19	4
BP	GO:0035358	regulation of peroxisome proliferator activated receptor signaling pathway	4/1616	14/18670	0.02766	0.3257	0.302	TWIST1/ASXL2/ASXL1/SIRT1	4
BP	GO:0046479	glycosphingolipid catabolic process	4/1616	14/18670	0.02766	0.3257	0.302	NAGA/GBA/GALC/GM2A	4
BP	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning	4/1616	14/18670	0.02766	0.3257	0.302	GORAB/IFT122/GPR161/MKS1	4
BP	GO:0080009	mRNA methylation	4/1616	14/18670	0.02766	0.3257	0.302	WTAP/PCIF1/METTL16/TRMT10C	4
BP	GO:1904923	regulation of autophagy of mitochondrion in response to mitochondrial depolarization	4/1616	14/18670	0.02766	0.3257	0.302	MUL1/GBA/SMURF1/HK2	4
BP	GO:0001666	response to hypoxia	42/1616	359/18670	0.02783	0.327	0.3033	EGLN2/ENDOG/HIF1AN/HMOX2/NOTCH1/SRF/EGLN3/ERCC2/NR4A2/AHCY/CXCR4/NFE2L2/CREBBP/THBS1/LOXL2/XRCC1/PSME2/RORA/MYC/CDKN1B/TWIST1/BNIP3/PSMD5/ZFP36L1/MMP14/PSMA5/SLC2A1/PRKCE/PSMA2/GATA6/EP300/HK2/PSME4/MECP2/UCP2/PSMB3/RAF1/ALAD/PSMD2/SIRT1/TGFBR2/SLC11A2	42
BP	GO:1901605	alpha-amino acid metabolic process	28/1616	222/18670	0.02802	0.3283	0.3044	EGLN2/PSAT1/SERINC3/HMGCL/GART/EGLN3/ALDH8A1/MTHFS/AHCY/AMDHD1/BCAT1/DDAH2/PSPH/GFPT2/PARK7/GCAT/SEPSECS/MTHFD2L/NOS3/ALDH4A1/ALDH18A1/MECP2/FAH/HGD/CAD/ASS1/CTH/DLD	28
BP	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic	7/1616	35/18670	0.02811	0.3283	0.3044	EDC3/DCP1A/DDX6/EXOSC5/DIS3/DCP2/WDR61	7
BP	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	7/1616	35/18670	0.02811	0.3283	0.3044	NMT1/HIP1R/GSK3A/BID/YWHAZ/TFDP2/TP63	7
BP	GO:0051053	negative regulation of DNA metabolic process	21/1616	156/18670	0.02818	0.3284	0.3046	STAG2/TERF2IP/CHEK2/MEN1/ZNF830/DUSP1/DFFA/XRCC1/ACD/NUDT16L1/TWIST1/TSPYL2/RMI2/AICDA/DCP2/TNKS/TNKS2/HNRNPA1/BCL6/TET1/MAPT-AS1	21
BP	GO:0019216	regulation of lipid metabolic process	47/1616	410/18670	0.02881	0.3347	0.3104	CISH/CDK4/NRBF2/FDPS/CARM1/PMVK/ORMDL2/SIK1/MVK/SOCS3/PNPLA2/ADIPOR2/NR1D2/CREBBP/INSIG1/TRIB3/SAMD8/PIK3R1/CEACAM1/PRKAG2/WDR91/SOCS2/RORA/CYP51A1/BSCL2/TWIST1/WDR81/P2RY12/AGAP2/KLF4/CNEP1R1/ATG14/DHCR7/GPAM/THRA/PRKCE/TGS1/ACSL3/NR1D1/IRS2/CHD9/ABHD6/SOCS5/GFI1/NCOA2/APOA1/SIRT1	47
BP	GO:0072413	signal transduction involved in mitotic cell cycle checkpoint	10/1616	59/18670	0.02894	0.3347	0.3104	PRMT1/CARM1/CHEK2/CDKN1B/BTG2/GADD45A/EP300/TFDP2/CNOT6L/CDKN1A	10
BP	GO:1902402	signal transduction involved in mitotic DNA damage checkpoint	10/1616	59/18670	0.02894	0.3347	0.3104	PRMT1/CARM1/CHEK2/CDKN1B/BTG2/GADD45A/EP300/TFDP2/CNOT6L/CDKN1A	10
BP	GO:1902403	signal transduction involved in mitotic DNA integrity checkpoint	10/1616	59/18670	0.02894	0.3347	0.3104	PRMT1/CARM1/CHEK2/CDKN1B/BTG2/GADD45A/EP300/TFDP2/CNOT6L/CDKN1A	10
BP	GO:0071482	cellular response to light stimulus	18/1616	129/18670	0.02926	0.3356	0.3113	SDE2/CRY2/ZBTB1/HYAL3/NMT1/CREBBP/CASP9/PIK3R1/PDE6G/MYC/OPN3/DDB1/EP300/ATF4/MFAP4/EIF2AK4/CDKN1A/SIRT1	18
BP	GO:0030866	cortical actin cytoskeleton organization	8/1616	43/18670	0.02928	0.3356	0.3113	CDK5/IKBKB/TIGD5/PDCD6IP/RAB13/EPB41L2/WASL/NCKAP1	8
BP	GO:0072348	sulfur compound transport	8/1616	43/18670	0.02928	0.3356	0.3113	LRRC8A/SLC25A30/SLC26A11/SLC3A1/SLC7A9/CTNS/SLC25A19/SLC26A2	8
BP	GO:0071356	cellular response to tumor necrosis factor	35/1616	291/18670	0.02939	0.3356	0.3113	SPATA2/GBP1/TNFRSF6B/NFKBIA/IKBKB/HYAL3/ZC3H12A/PYCARD/TNFAIP3/NFE2L2/THBS1/MAP3K14/PSME2/RORA/CD27/GBA/HSPA1A/TXNDC17/PSMD5/RBCK1/SMPD4/ZFP36L1/PSMA5/CEBPA/PSMA2/ZFP36L2/NR1D1/PSME4/COL1A1/ASS1/PSMB3/KRT8/APOA1/PSMD2/SIRT1	35
BP	GO:1903509	liposaccharide metabolic process	16/1616	111/18670	0.0294	0.3356	0.3113	ESYT2/PIGA/ST6GALNAC4/NAGA/ST3GAL5/ST3GAL2/CTSA/GBA/GALC/SMPD4/PIGH/GM2A/MPPE1/PIGL/DPM1/GPAA1	16
BP	GO:0031050	dsRNA processing	9/1616	51/18670	0.02943	0.3356	0.3113	ZC3H12A/SNIP1/ZC3H7A/DICER1/BMP4/SRRT/ZC3H10/MRPL44/TSN	9
BP	GO:0070918	production of small RNA involved in gene silencing by RNA	9/1616	51/18670	0.02943	0.3356	0.3113	ZC3H12A/SNIP1/ZC3H7A/DICER1/BMP4/SRRT/ZC3H10/MRPL44/TSN	9
BP	GO:0006760	folic acid-containing compound metabolic process	6/1616	28/18670	0.02996	0.3383	0.3138	GART/MTHFS/GCH1/DHFR/MTHFD2L/MTHFD1L	6
BP	GO:0061615	glycolytic process through fructose-6-phosphate	6/1616	28/18670	0.02996	0.3383	0.3138	HK1/GALK1/HK2/PFKL/FOXK2/PFKP	6
BP	GO:0061620	glycolytic process through glucose-6-phosphate	6/1616	28/18670	0.02996	0.3383	0.3138	HK1/GALK1/HK2/PFKL/FOXK2/PFKP	6
BP	GO:0070198	protein localization to chromosome, telomeric region	6/1616	28/18670	0.02996	0.3383	0.3138	CCT5/TERF2IP/CCT6A/ACD/TNKS/TNKS2	6
BP	GO:2000108	positive regulation of leukocyte apoptotic process	6/1616	28/18670	0.02996	0.3383	0.3138	PRELID1/LGALS14/LGALS9/RAPGEF2/FNIP1/SIRT1	6
BP	GO:1902105	regulation of leukocyte differentiation	33/1616	272/18670	0.03021	0.3404	0.3157	CD83/IRF7/PTPN6/ROR2/ZBTB1/IL34/PRELID1/ZC3H12A/TRAF6/PIK3R1/CEACAM1/HAX1/FSTL3/MYC/CD27/RASSF2/FADD/BMP4/ZFP36L1/MMP14/IL12A/SOS1/LGALS9/CD46/LILRB3/ZFP36L2/RC3H2/JAK3/BCL6/PNP/SOCS5/TOB2/TGFBR2	33
BP	GO:0000966	RNA 5'-end processing	5/1616	21/18670	0.03043	0.341	0.3162	RPP14/ABT1/POP1/TRMT10C/RPP40	5
BP	GO:0032682	negative regulation of chemokine production	5/1616	21/18670	0.03043	0.341	0.3162	MUL1/C1QTNF3/KLF4/LGALS9/SOCS5	5
BP	GO:0036344	platelet morphogenesis	5/1616	21/18670	0.03043	0.341	0.3162	PTPN6/SRF/CASP9/WDR1/EP300	5
BP	GO:0051090	regulation of DNA-binding transcription factor activity	49/1616	432/18670	0.03076	0.344	0.3191	PIM1/MXI1/NFKBIE/PARP10/NFKBIA/DAP/IKBKB/SRF/CARM1/SMARCB1/TERF2IP/FZD6/ZC3H12A/PYCARD/MEN1/JMY/SIK1/TRAF6/TNFAIP3/MAP3K7/PRDX3/TCF7L2/SRI/PARK7/BCL10/MAPK11/RNF25/STK36/NFKB2/TWIST1/HSPA1A/PRMT2/KLF4/HDAC2/RBCK1/IL18RAP/CCDC22/G3BP2/LGALS9/EP300/CAMK1D/WNT10B/EIF2AK4/PRKCI/CTH/DDX58/RLIM/GFI1/SIRT1	49
BP	GO:0016239	positive regulation of macroautophagy	11/1616	68/18670	0.03095	0.3454	0.3203	PIM2/SH3GLB1/MAP3K7/SMCR8/SMURF1/BNIP3/IRGM/TSC1/HTT/SPTLC2/SIRT1	11
BP	GO:0042157	lipoprotein metabolic process	18/1616	130/18670	0.03132	0.3489	0.3236	ZDHHC16/PIGA/PPM1B/NMT1/APOL1/ABHD13/ZDHHC9/GBA/GOLGA7B/PIGH/MPPE1/IRGM/APOM/PIGL/DPM1/PPM1A/APOA1/GPAA1	18
BP	GO:0033013	tetrapyrrole metabolic process	10/1616	60/18670	0.03214	0.3557	0.3299	HMOX2/MMACHC/IREB2/SLC25A38/SRRD/RSAD1/IBA57/ALAD/CTRC/SLC11A2	10
BP	GO:0043966	histone H3 acetylation	10/1616	60/18670	0.03214	0.3557	0.3299	PER1/SMARCB1/MAP3K7/ING5/KAT7/MBIP/BRPF1/BRD1/TADA1/SIRT1	10
BP	GO:0051236	establishment of RNA localization	25/1616	196/18670	0.03228	0.3557	0.3299	HNRNPA1L2/NUP50/POLR2D/MVP/TOMM20L/SFPQ/DDX19B/ENY2/NUP133/AAAS/NUP35/ZFP36L1/G3BP2/SRSF11/TNKS/SENP2/SLU7/AKAP8L/SRRM1/SIDT1/HNRNPA1/TSC1/WDR33/UPF1/TGFBR2	25
BP	GO:0006732	coenzyme metabolic process	46/1616	403/18670	0.03228	0.3557	0.3299	NUP50/HMGCL/GART/PARP10/HK1/PMVK/PGAM4/MAT2B/MTHFS/AHCY/RFK/MVK/PDHA1/PRKAG2/TALDO1/CBR4/GCH1/NUP133/COQ10B/DHFR/METTL16/MBIP/ASPDH/AAAS/MTHFD2L/NUP35/SLC2A1/PFKFB3/GALK1/PGK2/ACSL3/MAT2A/HK2/PFKL/VCP/COQ7/MTHFD1L/FOXK2/COQ9/PNPO/PPTC7/PFKFB4/PFKP/DLD/MPC1/ENTPD5	46
BP	GO:0051851	modification by host of symbiont morphology or physiology	12/1616	77/18670	0.03234	0.3557	0.3299	CCNT1/TBC1D20/TAF11/SMARCB1/ZC3H12A/AZU1/RAB9A/NAPEPLD/CFL1/EP300/EIF2AK4/ZNF639	12
BP	GO:1901224	positive regulation of NIK/NF-kappaB signaling	12/1616	77/18670	0.03234	0.3557	0.3299	TNFRSF10B/TERF2IP/TRAF6/MAP3K7/NR3C2/CD27/RBCK1/LGALS9/EP300/ZFP91/RC3H2/TRAF4	12
BP	GO:0032205	negative regulation of telomere maintenance	7/1616	36/18670	0.03237	0.3557	0.3299	TERF2IP/XRCC1/ACD/DCP2/TNKS/TNKS2/HNRNPA1	7
BP	GO:0002706	regulation of lymphocyte mediated immunity	20/1616	149/18670	0.03248	0.3557	0.3299	PTPN6/ZBTB1/TRAF6/RSAD2/MAP3K7/CEACAM1/VAV1/FADD/IL18RAP/IL12A/ATAD5/LGALS9/CLCF1/MICA/IL27RA/HLA-H/MICB/HLA-A/BCL6/HLA-C	20
BP	GO:2001056	positive regulation of cysteine-type endopeptidase activity	20/1616	149/18670	0.03248	0.3557	0.3299	PDCD6/DAP/EGLN3/TNFRSF10B/PYCARD/PDCD5/HIP1R/MUL1/CASP9/CASP10/MYC/CTSH/TNFSF10/BCL10/FADD/BID/LGALS9/VCP/SIRT1/IFT57	20
BP	GO:1903573	negative regulation of response to endoplasmic reticulum stress	8/1616	44/18670	0.03316	0.3621	0.3358	BFAR/PPP1R15B/PARK7/HSPA1A/DNAJB9/BCL2L1/HERPUD1/YOD1	8
BP	GO:0001776	leukocyte homeostasis	13/1616	86/18670	0.03326	0.3621	0.3358	SIT1/LAT/TNFAIP3/BCL10/FADD/SH2B3/TSC22D3/SOS1/LGALS9/CORO1A/RC3H2/JAK3/BAP1	13
BP	GO:0001942	hair follicle development	13/1616	86/18670	0.03326	0.3621	0.3358	GORAB/NOTCH1/ERCC2/FZD6/TMEM79/ACVR1B/HDAC2/SOS1/DKK4/WNT10B/KRT17/TP63/NSUN2	13
BP	GO:1903076	regulation of protein localization to plasma membrane	14/1616	95/18670	0.03379	0.3665	0.3399	GBP1/CDK5/CSK/PIK3R1/ACTB/BCL2L1/MMP14/RAB11FIP2/ITGA3/PRKCE/RANGRF/ACSL3/GRASP/PRKCI	14
BP	GO:0034101	erythrocyte homeostasis	17/1616	122/18670	0.03383	0.3665	0.3399	PRMT1/SRF/ERCC2/ISG15/IREB2/L3MBTL3/ACVR1B/BMP4/HSPA1A/SLC25A38/ZFP36L1/SH2B3/THRA/ZNF16/JAK3/BCL6/SLC11A2	17
BP	GO:1903829	positive regulation of cellular protein localization	38/1616	324/18670	0.03385	0.3665	0.3399	CCT5/CTDSPL2/RAC2/CDK5/ZC3H12A/NMT1/PDCD5/SAR1A/CCT6A/DTX3L/SH3GLB1/PIK3R1/PDCD10/TCF7L2/GSK3A/KAT7/PARK7/BID/RAB11FIP2/TSG101/ITGA3/PRKCE/RANGRF/YWHAZ/ACSL3/EPB41L2/MGAT3/XPO4/CCDC88A/TFDP2/BAP1/HSPA1L/PPM1A/MAP1A/TP63/PRKCI/GPSM2/PDZK1	38
BP	GO:0043244	regulation of protein complex disassembly	16/1616	113/18670	0.03402	0.3666	0.34	PHF23/CAMSAP3/CFL2/SWAP70/WDR1/SMCR8/GBA/SCAF8/TWF2/BNIP3/CAPZB/CFL1/TWF1/IRGM/MAP1A/UPF1	16
BP	GO:0002221	pattern recognition receptor signaling pathway	25/1616	197/18670	0.03405	0.3666	0.34	IRF7/NFKBIA/IKBKB/TLR5/TRAF6/MAPKAPK3/TNFAIP3/RSAD2/ANKRD17/UNC93B1/MAP3K7/BCL10/FADD/HSPA1A/ZCCHC3/RAB11FIP2/OTUD4/GPATCH3/PRKCE/RNF125/IRGM/CTSK/NR1D1/DDX58/GFI1	25
BP	GO:0010952	positive regulation of peptidase activity	25/1616	197/18670	0.03405	0.3666	0.34	PDCD6/DAP/EGLN3/TNFRSF10B/PRELID1/PYCARD/PDCD5/HIP1R/MUL1/CASP9/GRN/PSME2/CASP10/MYC/CTSH/TNFSF10/BCL10/FADD/BID/LGALS9/PSME4/AKIRIN2/VCP/SIRT1/IFT57	25
BP	GO:0010950	positive regulation of endopeptidase activity	23/1616	178/18670	0.03412	0.3667	0.3401	PDCD6/DAP/EGLN3/TNFRSF10B/PRELID1/PYCARD/PDCD5/HIP1R/MUL1/CASP9/PSME2/CASP10/MYC/CTSH/TNFSF10/BCL10/FADD/BID/LGALS9/AKIRIN2/VCP/SIRT1/IFT57	23
BP	GO:0019882	antigen processing and presentation	28/1616	226/18670	0.03428	0.3677	0.341	MR1/IKBKB/DCTN4/ERAP2/PYCARD/TRAF6/THBS1/KIF22/SNAP23/PSME2/CTSH/AP2S1/DNM2/PSMD5/TAP1/CAPZB/PSMA5/IFI30/PSMA2/HLA-H/PSME4/DYNC1LI2/HLA-A/PSMB3/DYNLL1/HLA-C/RAB10/PSMD2	28
BP	GO:0072525	pyridine-containing compound biosynthetic process	20/1616	150/18670	0.03454	0.3687	0.342	PSAT1/NUP50/PARP10/HK1/PGAM4/PRKAG2/NUP133/ASPDH/AAAS/NUP35/PFKFB3/GALK1/PGK2/HK2/PFKL/FOXK2/PNPO/PFKFB4/PFKP/ENTPD5	20
BP	GO:0018394	peptidyl-lysine acetylation	22/1616	169/18670	0.03502	0.3687	0.342	PER1/SMARCB1/CREBBP/MORF4L1/MAP3K7/ACTL6A/ING5/KAT7/MBIP/TWIST1/KANSL2/HDAC2/BRPF1/RSF1/ATAT1/GTF3C4/EP300/PHF20/MECP2/BRD1/TADA1/SIRT1	22
BP	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	6/1616	29/18670	0.0351	0.3687	0.342	MEN1/CREBBP/THBS1/CDKN2B/LRG1/EP300	6
BP	GO:0048730	epidermis morphogenesis	6/1616	29/18670	0.0351	0.3687	0.342	GORAB/NOTCH1/TMEM79/KLF4/KRT17/TP63	6
BP	GO:0060765	regulation of androgen receptor signaling pathway	6/1616	29/18670	0.0351	0.3687	0.342	PHB/PARK7/PRMT2/EP300/SAFB2/SIRT1	6
BP	GO:0061099	negative regulation of protein tyrosine kinase activity	6/1616	29/18670	0.0351	0.3687	0.342	MVP/SOCS4/TSG101/CBLB/ZGPAT/SOCS5	6
BP	GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus	6/1616	29/18670	0.0351	0.3687	0.342	MEN1/CREBBP/THBS1/CDKN2B/LRG1/EP300	6
BP	GO:2000515	negative regulation of CD4-positive, alpha-beta T cell activation	6/1616	29/18670	0.0351	0.3687	0.342	ZC3H12A/LGALS9/RC3H2/JAK3/BCL6/SOCS5	6
BP	GO:0002467	germinal center formation	4/1616	15/18670	0.0352	0.3687	0.342	CXCL13/TNFAIP3/NFKB2/BCL6	4
BP	GO:0007039	protein catabolic process in the vacuole	4/1616	15/18670	0.0352	0.3687	0.342	GBA/TMEM199/MGAT3/ATP13A2	4
BP	GO:0018216	peptidyl-arginine methylation	4/1616	15/18670	0.0352	0.3687	0.342	PRMT1/CARM1/PRDM4/PRMT2	4
BP	GO:0034616	response to laminar fluid shear stress	4/1616	15/18670	0.0352	0.3687	0.342	NFE2L2/KLF4/ADAM9/ASS1	4
BP	GO:0051127	positive regulation of actin nucleation	4/1616	15/18670	0.0352	0.3687	0.342	WHAMM/WASL/FMN1/NCKAP1	4
BP	GO:1903313	positive regulation of mRNA metabolic process	12/1616	78/18670	0.03533	0.3694	0.3426	ZC3H12A/TNRC6B/METTL16/BTG2/ZFP36L1/RBM3/FTO/GTPBP1/ZFP36L2/YTHDF3/CNOT6L/UPF1	12
BP	GO:0045598	regulation of fat cell differentiation	18/1616	132/18670	0.03576	0.3719	0.3449	CARM1/ZC3H12A/INSIG1/TRIB3/RORA/NAPEPLD/ZFP36L1/CEBPA/METRNL/ATAT1/FTO/ASXL2/ZFP36L2/NR1D1/MEX3C/ASXL1/WNT10B/SIRT1	18
BP	GO:0006479	protein methylation	23/1616	179/18670	0.03607	0.3719	0.3449	PRMT1/EHMT2/PHF1/CARM1/SMARCB1/MEN1/TRMT112/PRDM4/PAGR1/PRMT2/NTMT1/BTG2/ASH1L/FAM98B/ZNF274/JARID2/BRD4/MECP2/SETD1B/WDR61/TET1/GFI1/SIRT1	23
BP	GO:0006611	protein export from nucleus	23/1616	179/18670	0.03607	0.3719	0.3449	CTDSPL2/NUP50/CDK5/POLR2D/STRADB/DDX19B/TCF7L2/ENY2/NUP133/PARK7/AAAS/NUP35/SMURF1/SRSF11/XPO4/SLU7/AKAP8L/SRRM1/CSE1L/TSC1/PPM1A/WDR33/UPF1	23
BP	GO:0008213	protein alkylation	23/1616	179/18670	0.03607	0.3719	0.3449	PRMT1/EHMT2/PHF1/CARM1/SMARCB1/MEN1/TRMT112/PRDM4/PAGR1/PRMT2/NTMT1/BTG2/ASH1L/FAM98B/ZNF274/JARID2/BRD4/MECP2/SETD1B/WDR61/TET1/GFI1/SIRT1	23
BP	GO:0071347	cellular response to interleukin-1	23/1616	179/18670	0.03607	0.3719	0.3449	PELI2/GBP1/NFKBIA/IKBKB/HYAL3/ZC3H12A/PYCARD/TRAF6/MAP3K7/MAP3K3/PSME2/PLCB1/RORA/MAPK11/PSMD5/PSMA5/OTUD4/PSMA2/NR1D1/PSME4/UPF1/PSMB3/PSMD2	23
BP	GO:0030218	erythrocyte differentiation	16/1616	114/18670	0.03652	0.3719	0.3449	PRMT1/SRF/ERCC2/ISG15/L3MBTL3/ACVR1B/BMP4/HSPA1A/SLC25A38/ZFP36L1/SH2B3/THRA/ZNF16/JAK3/BCL6/SLC11A2	16
BP	GO:0098876	vesicle-mediated transport to the plasma membrane	14/1616	96/18670	0.03653	0.3719	0.3449	GOLPH3L/CSK/SNX27/TRIM23/SYS1/NSG1/EXOC8/DNM2/CCDC22/ACSL3/GRASP/EXOC6B/RAB10/KIF13A	14
BP	GO:0002708	positive regulation of lymphocyte mediated immunity	15/1616	105/18670	0.03664	0.3719	0.3449	ZBTB1/TRAF6/RSAD2/MAP3K7/VAV1/FADD/IL18RAP/IL12A/ATAD5/CLCF1/MICA/HLA-H/MICB/HLA-A/HLA-C	15
BP	GO:0002097	tRNA wobble base modification	5/1616	22/18670	0.03666	0.3719	0.3449	ELP5/TRMU/ALKBH8/DPH3P1/CTU1	5
BP	GO:0019883	antigen processing and presentation of endogenous antigen	5/1616	22/18670	0.03666	0.3719	0.3449	ERAP2/TAP1/HLA-H/HLA-A/HLA-C	5
BP	GO:0033622	integrin activation	5/1616	22/18670	0.03666	0.3719	0.3449	CXCL13/RASIP1/P2RY12/KIF14/FERMT3	5
BP	GO:0034311	diol metabolic process	5/1616	22/18670	0.03666	0.3719	0.3449	GCH1/DHFR/GBA/ASAH2B/SPTLC2	5
BP	GO:0045943	positive regulation of transcription by RNA polymerase I	5/1616	22/18670	0.03666	0.3719	0.3449	SMARCB1/WDR75/ATF4/UTP15/DDX11	5
BP	GO:0071359	cellular response to dsRNA	5/1616	22/18670	0.03666	0.3719	0.3449	IFIT1/MUL1/ZCCHC3/PQBP1/DDX58	5
BP	GO:0097320	plasma membrane tubulation	5/1616	22/18670	0.03666	0.3719	0.3449	WHAMM/SH3GLB1/DNM2/WASL/BIN3	5
BP	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus	5/1616	22/18670	0.03666	0.3719	0.3449	NOTCH1/NFE2L2/EP300/ATF4/CHD6	5
BP	GO:2000773	negative regulation of cellular senescence	5/1616	22/18670	0.03666	0.3719	0.3449	ZKSCAN3/MAP3K3/TWIST1/BCL6/SIRT1	5
BP	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	9/1616	53/18670	0.03676	0.3723	0.3453	PTPN6/MVP/SOCS4/SOCS3/SH2B3/TSG101/CBLB/ZGPAT/SOCS5	9
BP	GO:0043029	T cell homeostasis	7/1616	37/18670	0.03705	0.3732	0.3462	SIT1/FADD/TSC22D3/LGALS9/CORO1A/RC3H2/JAK3	7
BP	GO:0043243	positive regulation of protein complex disassembly	7/1616	37/18670	0.03705	0.3732	0.3462	CFL2/WDR1/SMCR8/GBA/BNIP3/CFL1/IRGM	7
BP	GO:0051567	histone H3-K9 methylation	7/1616	37/18670	0.03705	0.3732	0.3462	EHMT2/SMARCB1/ASH1L/ZNF274/JARID2/MECP2/SIRT1	7
BP	GO:0070988	demethylation	11/1616	70/18670	0.03735	0.3753	0.3481	MMACHC/KDM2A/CYP2D6/CYP51A1/AICDA/OTUD4/JARID2/FTO/PHF2/TET1/KDM8	11
BP	GO:1902743	regulation of lamellipodium organization	8/1616	45/18670	0.03738	0.3753	0.3481	RAC2/DNM2/TWF2/CAPZB/CORO1B/TWF1/BIN3/NCKAP1	8
BP	GO:1901988	negative regulation of cell cycle phase transition	32/1616	267/18670	0.03751	0.3759	0.3486	CDK4/PRMT1/FOXN3/CARM1/CDK2AP2/CHEK2/MEN1/ZNF830/DUSP1/MYO16/PSME2/CDKN2B/CDKN1B/PRMT2/BTG2/RPA2/KLF4/PSMD5/CDKN2D/ZFP36L1/PSMA5/GADD45A/PSMA2/ZFP36L2/EP300/PSME4/TFDP2/CNOT6L/PSMB3/GPR132/CDKN1A/PSMD2	32
BP	GO:0018393	internal peptidyl-lysine acetylation	21/1616	161/18670	0.03803	0.3805	0.3529	PER1/SMARCB1/CREBBP/MORF4L1/MAP3K7/ACTL6A/ING5/KAT7/MBIP/TWIST1/KANSL2/BRPF1/RSF1/ATAT1/GTF3C4/EP300/PHF20/MECP2/BRD1/TADA1/SIRT1	21
BP	GO:0006414	translational elongation	18/1616	133/18670	0.03814	0.381	0.3533	MRPS5/MRPS18C/MRPS26/MRPL51/TRNAU1AP/TSFM/SEPSECS/MRPL54/MRPL15/MRPL44/ERAL1/GTPBP1/ABTB1/MRPS21/MRPL24/USP16/DPH3P1/DPH2	18
BP	GO:0006446	regulation of translational initiation	12/1616	79/18670	0.0385	0.3832	0.3554	EIF1B/POLR2D/MIF4GD/EIF1/PPP1R15B/EIF4A2/RBM4/RPS6KB2/ATF4/YTHDF3/PAIP2/EIF2AK4	12
BP	GO:0006006	glucose metabolic process	26/1616	209/18670	0.0385	0.3832	0.3554	BRAT1/HK1/PPP1R3D/SIK1/PDHA1/PIK3CA/TKTL1/GDPGP1/RORA/SORD/GSK3A/C1QTNF3/DDB1/PGK2/EP300/HK2/NR1D1/ATF4/IRS2/PFKL/FOXK2/PFKP/OAS1/NCOA2/PASK/SIRT1	26
BP	GO:0001838	embryonic epithelial tube formation	17/1616	124/18670	0.03872	0.3836	0.3557	SEMA4C/FZD6/TRAF6/BCL10/BMP4/TWIST1/VASP/GLMN/CFL1/IFT122/TSC1/MTHFD1L/ALX1/CTHRC1/NPHP3/MKS1/IFT57	17
BP	GO:0051028	mRNA transport	20/1616	152/18670	0.03896	0.3836	0.3557	HNRNPA1L2/NUP50/POLR2D/MVP/DDX19B/ENY2/NUP133/AAAS/NUP35/ZFP36L1/G3BP2/SRSF11/TNKS/SENP2/SLU7/AKAP8L/SRRM1/HNRNPA1/WDR33/UPF1	20
BP	GO:0006096	glycolytic process	16/1616	115/18670	0.03915	0.3836	0.3557	NUP50/HK1/PGAM4/PRKAG2/NUP133/AAAS/NUP35/PFKFB3/GALK1/PGK2/HK2/PFKL/FOXK2/PFKFB4/PFKP/ENTPD5	16
BP	GO:0010927	cellular component assembly involved in morphogenesis	16/1616	115/18670	0.03915	0.3836	0.3557	TBC1D20/SRF/MYH10/ACTG1/ERCC2/CFL2/WDR1/MPP5/DICER1/TNNT3/TBPL1/RFX2/CCDC136/MYOM2/ACRBP/KRT8	16
BP	GO:0022404	molting cycle process	13/1616	88/18670	0.03916	0.3836	0.3557	GORAB/NOTCH1/ERCC2/FZD6/TMEM79/ACVR1B/HDAC2/SOS1/DKK4/WNT10B/KRT17/TP63/NSUN2	13
BP	GO:0022405	hair cycle process	13/1616	88/18670	0.03916	0.3836	0.3557	GORAB/NOTCH1/ERCC2/FZD6/TMEM79/ACVR1B/HDAC2/SOS1/DKK4/WNT10B/KRT17/TP63/NSUN2	13
BP	GO:0032088	negative regulation of NF-kappaB transcription factor activity	13/1616	88/18670	0.03916	0.3836	0.3557	PARP10/NFKBIA/DAP/ZC3H12A/PYCARD/TNFAIP3/PRMT2/KLF4/RBCK1/CCDC22/G3BP2/GFI1/SIRT1	13
BP	GO:0098773	skin epidermis development	13/1616	88/18670	0.03916	0.3836	0.3557	GORAB/NOTCH1/ERCC2/FZD6/TMEM79/ACVR1B/HDAC2/SOS1/DKK4/WNT10B/KRT17/TP63/NSUN2	13
BP	GO:1903321	negative regulation of protein modification by small protein conjugation or removal	13/1616	88/18670	0.03916	0.3836	0.3557	PARP10/CDK5/USP4/ISG15/TNFAIP3/DTX3L/PARK7/HSPA1A/SPOPL/SENP2/GLMN/PRKCE/DNAJA1	13
BP	GO:0043901	negative regulation of multi-organism process	22/1616	171/18670	0.0392	0.3836	0.3557	IFITM2/PARP10/PPM1B/ISG15/ZC3H12A/IFIT1/TNFAIP3/RSAD2/MUL1/TRIM11/BST2/RNF26/AICDA/IFITM1/IFITM3/GPATCH3/RNF125/MICB/EIF2AK4/OAS1/ISG20/ZNF639	22
BP	GO:0044774	mitotic DNA integrity checkpoint	15/1616	106/18670	0.0394	0.3849	0.357	PRMT1/FOXN3/CARM1/CHEK2/ZNF830/CDKN1B/BTG2/RPA2/GADD45A/STK33/EP300/TFDP2/CNOT6L/MUS81/CDKN1A	15
BP	GO:0045930	negative regulation of mitotic cell cycle	39/1616	338/18670	0.03967	0.3869	0.3588	CDK4/PRMT1/FOXN3/CARM1/CDK2AP2/CHEK2/ZNF830/DUSP1/HECA/MYO16/PSME2/CDKN2B/CDKN1B/BMP4/PRMT2/BTG2/RPA2/KLF4/PSMD5/BCL2L1/CDKN2D/ZFP36L1/PSMA5/GADD45A/TNKS/MAD2L1BP/PSMA2/STK33/ZFP36L2/EP300/PSME4/TFDP2/CNOT6L/PSMB3/BCL6/GPR132/MUS81/CDKN1A/PSMD2	39
BP	GO:0045926	negative regulation of growth	30/1616	249/18670	0.04041	0.393	0.3645	OSGIN2/PHB/NOTCH1/CDK5/SERTAD2/GNG4/SEMA4C/ADIPOR2/MUL1/SOCS2/SEMA4F/GSK3A/ING5/ACVR1B/CDKN1B/MAPK11/BMP4/HSPA1A/TSPYL2/CDKN2D/BST2/JARID2/CDKN2AIP/OSGIN1/ADRB1/BCL6/ARHGAP4/CDKN1A/SIRT1/TGFBR2	30
BP	GO:0006766	vitamin metabolic process	18/1616	134/18670	0.04064	0.393	0.3645	PSAT1/VKORC1/VKORC1L1/MMACHC/MTHFS/RFK/SLC52A2/TKTL1/ACP5/DHFR/CYP4F12/MTHFD2L/SLC2A1/SLC25A19/MTHFD1L/PNPO/GFI1/CTRC	18
BP	GO:0001844	protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	6/1616	30/18670	0.04077	0.393	0.3645	MOAP1/NMT1/BID/YWHAZ/TFDP2/TP63	6
BP	GO:0006362	transcription elongation from RNA polymerase I promoter	6/1616	30/18670	0.04077	0.393	0.3645	CD3EAP/GTF2H5/ERCC2/POLR2H/MNAT1/GTF2H4	6
BP	GO:0038111	interleukin-7-mediated signaling pathway	6/1616	30/18670	0.04077	0.393	0.3645	CISH/BRWD1/SOCS2/CRLF2/IRS2/JAK3	6
BP	GO:0090200	positive regulation of release of cytochrome c from mitochondria	6/1616	30/18670	0.04077	0.393	0.3645	MOAP1/PYCARD/PDCD5/TNFSF10/BID/BNIP3	6
BP	GO:1902751	positive regulation of cell cycle G2/M phase transition	6/1616	30/18670	0.04077	0.393	0.3645	CDK4/ATAD5/BRD4/MECP2/WNT10B/CDC25B	6
BP	GO:0071478	cellular response to radiation	24/1616	191/18670	0.0411	0.3955	0.3668	SDE2/CRY2/GTF2H5/ZBTB1/HYAL3/CHEK2/NMT1/CREBBP/CASP9/PIK3R1/TLK2/PDE6G/MYC/DNM2/BCL2L1/OPN3/DDB1/GADD45A/EP300/ATF4/MFAP4/EIF2AK4/CDKN1A/SIRT1	24
BP	GO:0006979	response to oxidative stress	50/1616	451/18670	0.04163	0.3989	0.37	ENDOG/HMOX2/VKORC1L1/ERCC2/RGS14/NR4A2/NDUFS2/ZC3H12A/NDUFA12/BRF2/TNFAIP3/NFE2L2/DUSP1/SFPQ/PRDX3/XRCC1/PRDX5/PDCD10/GCH1/MPV17/PPP1R15B/PARK7/DHFR/DNM2/HSPA1A/NOS3/KLF4/BNIP3/HDAC2/NUDT1/IL18RAP/FANCC/MMP14/MTF1/PTGS1/ADAM9/ADNP2/MGAT3/MICB/ATF4/SIGMAR1/GPX1/COL1A1/TSC1/UBE3A/CHD6/ALAD/ATP13A2/SIRT1/FBLN5	50
BP	GO:0006757	ATP generation from ADP	16/1616	116/18670	0.04191	0.3989	0.37	NUP50/HK1/PGAM4/PRKAG2/NUP133/AAAS/NUP35/PFKFB3/GALK1/PGK2/HK2/PFKL/FOXK2/PFKFB4/PFKP/ENTPD5	16
BP	GO:0002067	glandular epithelial cell differentiation	8/1616	46/18670	0.04195	0.3989	0.37	NOTCH1/MEN1/ASCL1/GSK3A/BMP4/GATA6/TP63/RFX3	8
BP	GO:0032480	negative regulation of type I interferon production	8/1616	46/18670	0.04195	0.3989	0.37	PPM1B/ISG15/PYCARD/TNFAIP3/REL/GPATCH3/RNF125/DDX58	8
BP	GO:0035196	production of miRNAs involved in gene silencing by miRNA	8/1616	46/18670	0.04195	0.3989	0.37	ZC3H12A/SNIP1/ZC3H7A/DICER1/BMP4/SRRT/ZC3H10/MRPL44	8
BP	GO:0001825	blastocyst formation	7/1616	38/18670	0.04215	0.3989	0.37	SRF/BYSL/ACTL6A/JUNB/MFNG/CCNB1IP1/TET1	7
BP	GO:0007223	Wnt signaling pathway, calcium modulating pathway	7/1616	38/18670	0.04215	0.3989	0.37	ROR2/FZD6/MAP3K7/PLCB1/PDE6G/TCF7L2/TNRC6B	7
BP	GO:0046636	negative regulation of alpha-beta T cell activation	7/1616	38/18670	0.04215	0.3989	0.37	ZC3H12A/LGALS9/RC3H2/JAK3/ADORA2A/BCL6/SOCS5	7
BP	GO:0046825	regulation of protein export from nucleus	7/1616	38/18670	0.04215	0.3989	0.37	CTDSPL2/CDK5/TCF7L2/PARK7/XPO4/AKAP8L/PPM1A	7
BP	GO:0097352	autophagosome maturation	7/1616	38/18670	0.04215	0.3989	0.37	PHF23/SMCR8/ATG14/SNAPIN/TSG101/IRGM/VCP	7
BP	GO:0001909	leukocyte mediated cytotoxicity	15/1616	107/18670	0.04231	0.3992	0.3702	PTPN6/CEACAM1/AZU1/CTSH/VAV1/FADD/IL18RAP/IL12A/LGALS9/MICA/HLA-H/MICB/CORO1A/HLA-A/HLA-C	15
BP	GO:0098781	ncRNA transcription	15/1616	107/18670	0.04231	0.3992	0.3702	CD3EAP/CCNT1/GTF3A/TAF11/SMARCB1/POLR2D/RPRD1B/BRF1/POLR2H/SRRT/GTF3C4/INTS12/DDX11/TAF13/ELL2	15
BP	GO:0006626	protein targeting to mitochondrion	14/1616	98/18670	0.04248	0.4002	0.3711	RAC2/GRPEL1/PDCD5/CHCHD4/TOMM20L/SLC25A6/SH3GLB1/HAX1/GSK3A/BID/TIMM13/TIMM10/BAP1/HSPA1L	14
BP	GO:0051170	import into nucleus	21/1616	163/18670	0.04261	0.4007	0.3717	NUP50/NFKBIA/IPO13/TMCO6/ZC3H12A/KPNA5/PIK3R1/NUP133/FAM53C/BMP4/NUP35/RANBP6/SMN2/HTATIP2/CBLB/RGPD6/FGF9/HNRNPA1/CSE1L/GEMIN7/CDKN1A	21
BP	GO:0000209	protein polyubiquitination	36/1616	310/18670	0.04303	0.4015	0.3724	PELI2/PARP10/TOPORS/TRAF6/TNFAIP3/FBXW4/DTX3L/PSME2/BFAR/FBXO22/SIAH2/ANAPC7/SMURF1/PSMD5/RBCK1/PSMA5/ZNRF1/RNF26/TNKS/PSMA2/FBXL3/RNF125/RNF167/FBXO21/RNF4/TRIM2/PSME4/ZFP91/RC3H2/TNKS2/SKP2/PSMB3/UBE3A/RLIM/LONRF1/PSMD2	36
BP	GO:0006297	nucleotide-excision repair, DNA gap filling	5/1616	23/18670	0.04361	0.4015	0.3724	POLD2/POLD4/XRCC1/RPA2/RPA1	5
BP	GO:0009147	pyrimidine nucleoside triphosphate metabolic process	5/1616	23/18670	0.04361	0.4015	0.3724	DTYMK/TBPL1/DCTPP1/CAD/AK3	5
BP	GO:0016578	histone deubiquitination	5/1616	23/18670	0.04361	0.4015	0.3724	ATXN7/ENY2/ASXL1/BAP1/USP16	5
BP	GO:0051570	regulation of histone H3-K9 methylation	5/1616	23/18670	0.04361	0.4015	0.3724	SMARCB1/ZNF274/JARID2/MECP2/SIRT1	5
BP	GO:0060055	angiogenesis involved in wound healing	5/1616	23/18670	0.04361	0.4015	0.3724	SRF/CXCR4/ADIPOR2/TNFAIP3/GPX1	5
BP	GO:0002070	epithelial cell maturation	4/1616	16/18670	0.0438	0.4015	0.3724	FEM1B/TMEM79/CDKN1A/RFX3	4
BP	GO:0019377	glycolipid catabolic process	4/1616	16/18670	0.0438	0.4015	0.3724	NAGA/GBA/GALC/GM2A	4
BP	GO:0033631	cell-cell adhesion mediated by integrin	4/1616	16/18670	0.0438	0.4015	0.3724	CXCL13/SWAP70/ADAM9/FERMT3	4
BP	GO:0036124	histone H3-K9 trimethylation	4/1616	16/18670	0.0438	0.4015	0.3724	SMARCB1/ZNF274/MECP2/SIRT1	4
BP	GO:0046519	sphingoid metabolic process	4/1616	16/18670	0.0438	0.4015	0.3724	KDSR/GBA/ASAH2B/SPTLC2	4
BP	GO:0050774	negative regulation of dendrite morphogenesis	4/1616	16/18670	0.0438	0.4015	0.3724	NLGN3/GORASP1/RAPGEF2/UBE3A	4
BP	GO:0060965	negative regulation of gene silencing by miRNA	4/1616	16/18670	0.0438	0.4015	0.3724	ZC3H12A/NEAT1/ELAVL1/ZC3H10	4
BP	GO:0061158	3'-UTR-mediated mRNA destabilization	4/1616	16/18670	0.0438	0.4015	0.3724	ZC3H12A/ZFP36L1/ZFP36L2/UPF1	4
BP	GO:0090335	regulation of brown fat cell differentiation	4/1616	16/18670	0.0438	0.4015	0.3724	NAPEPLD/METRNL/FTO/SIRT1	4
BP	GO:0099116	tRNA 5'-end processing	4/1616	16/18670	0.0438	0.4015	0.3724	RPP14/POP1/TRMT10C/RPP40	4
BP	GO:0006575	cellular modified amino acid metabolic process	25/1616	202/18670	0.044	0.4027	0.3734	EGLN2/CPT1B/SERINC3/GART/CPT1C/EGLN3/MMACHC/MTHFS/AHCY/NFE2L2/GSTM4/GCH1/CHAC2/PARK7/DHFR/MTHFD2L/SERINC1/ALDH4A1/ETHE1/LPCAT3/GPX1/CTNS/SULT1B1/MTHFD1L/ASS1	25
BP	GO:0110053	regulation of actin filament organization	31/1616	261/18670	0.04442	0.4059	0.3764	CFL2/PYCARD/JMY/HIP1R/WHAMMP3/WHAMM/ARPC1B/SWAP70/WDR1/PIK3R1/HAX1/GMFB/RICTOR/SPIRE2/TWF2/VASP/CAPZB/CORO1B/CFL1/PRKCE/TWF1/ARAP1/TMSB4Y/CORO1A/FCHSD1/TSC1/WASL/FMN1/NCKAP1/ARPC5/APOA1	31
BP	GO:0000077	DNA damage checkpoint	19/1616	145/18670	0.04491	0.4097	0.38	PRMT1/FOXN3/FEM1B/CARM1/CHEK2/ZNF830/CDKN1B/BTG2/RPA2/ETAA1/GADD45A/STK33/EP300/TFDP2/CNOT6L/EIF2AK4/MUS81/CDKN1A/ATRIP	19
BP	GO:0032781	positive regulation of ATPase activity	9/1616	55/18670	0.04525	0.4113	0.3814	AHSA1/ATP2A1/DNM2/ATP1B2/DNAJB1/GTF2H4/DNAJA1/TOR1AIP1/DYNLL1	9
BP	GO:0046916	cellular transition metal ion homeostasis	15/1616	108/18670	0.04537	0.4113	0.3814	SLC39A14/HMOX2/SCO1/IREB2/MYC/SRI/SCO2/SLC30A1/CCDC22/COX19/TMEM199/ATP6V1G1/SLC30A5/ATP13A2/SLC11A2	15
BP	GO:0051225	spindle assembly	15/1616	108/18670	0.04537	0.4113	0.3814	STAG2/SAC3D1/CHEK2/GOLGA6B/AAAS/HSPA1A/CSNK1D/CCSAP/TNKS/GOLGA6C/RNF4/RCC1/TUBGCP5/GPSM2/HAUS2	15
BP	GO:0060071	Wnt signaling pathway, planar cell polarity pathway	15/1616	108/18670	0.04537	0.4113	0.3814	ROR2/FZD6/PSME2/AP2S1/SMURF1/PSMD5/PSMA5/ARHGEF19/PSMA2/PSME4/PSMB3/CTHRC1/NPHP3/PSMD2/MKS1	15
BP	GO:0034109	homotypic cell-cell adhesion	12/1616	81/18670	0.04544	0.4113	0.3815	PTPN6/ACTG1/CEACAM1/ACTB/P2RY12/SH2B3/BLOC1S4/FERMT3/CD99/MYL12A/TSPAN32/FIBP	12
BP	GO:1902903	regulation of supramolecular fiber organization	40/1616	352/18670	0.04599	0.4156	0.3854	CAMSAP3/CFL2/PYCARD/JMY/HIP1R/WHAMMP3/WHAMM/ARPC1B/SWAP70/WDR1/PIK3R1/HAX1/FKBP4/GMFB/RICTOR/PARK7/CDKN1B/SPIRE2/HSPA1A/TWF2/VASP/CAPZB/CORO1B/CFL1/PRKCE/RANGRF/TWF1/ARAP1/TMSB4Y/CORO1A/MECP2/GPX1/FCHSD1/TSC1/WASL/MAP1A/FMN1/NCKAP1/ARPC5/APOA1	40
BP	GO:1903707	negative regulation of hemopoiesis	20/1616	155/18670	0.04635	0.4169	0.3866	PRMT1/NOTCH1/NFKBIA/ZC3H12A/NFE2L2/PIK3R1/CEACAM1/FSTL3/MYC/BMP4/ZFP36L1/MEIS2/LILRB3/GPR171/RC3H2/JAK3/WDR61/BCL6/SOCS5/TOB2	20
BP	GO:0002832	negative regulation of response to biotic stimulus	8/1616	47/18670	0.04688	0.4169	0.3866	PPM1B/TNFAIP3/MUL1/CEACAM1/RNF26/GPATCH3/RNF125/MICB	8
BP	GO:1900744	regulation of p38MAPK cascade	8/1616	47/18670	0.04688	0.4169	0.3866	PER1/PRMT1/ZC3H12A/DUSP1/MAP3K3/RELL1/GADD45A/PHLPP1	8
BP	GO:0006363	termination of RNA polymerase I transcription	6/1616	31/18670	0.04699	0.4169	0.3866	CD3EAP/GTF2H5/ERCC2/POLR2H/MNAT1/GTF2H4	6
BP	GO:0006506	GPI anchor biosynthetic process	6/1616	31/18670	0.04699	0.4169	0.3866	PIGA/PIGH/MPPE1/PIGL/DPM1/GPAA1	6
BP	GO:0030149	sphingolipid catabolic process	6/1616	31/18670	0.04699	0.4169	0.3866	NAGA/GBA/GALC/ASAH2B/SMPD4/GM2A	6
BP	GO:0043457	regulation of cellular respiration	6/1616	31/18670	0.04699	0.4169	0.3866	CISD1/PRELID1/PIK3CA/PARK7/BNIP3/VCP	6
BP	GO:0010257	NADH dehydrogenase complex assembly	10/1616	64/18670	0.04737	0.4169	0.3866	NDUFS7/NDUFS2/NDUFA12/BCS1L/NDUFB8/NDUFAF3/NDUFB11/NDUFB2/TIMMDC1/NDUFB10	10
BP	GO:0030032	lamellipodium assembly	10/1616	64/18670	0.04737	0.4169	0.3866	RAC2/WHAMM/DNM2/P2RY12/TWF2/CAPZB/TWF1/CCDC88A/BIN3/NCKAP1	10
BP	GO:0032981	mitochondrial respiratory chain complex I assembly	10/1616	64/18670	0.04737	0.4169	0.3866	NDUFS7/NDUFS2/NDUFA12/BCS1L/NDUFB8/NDUFAF3/NDUFB11/NDUFB2/TIMMDC1/NDUFB10	10
BP	GO:0043297	apical junction assembly	10/1616	64/18670	0.04737	0.4169	0.3866	IKBKB/SRF/WDR1/MPP5/PDCD6IP/PKN2/RAB13/PARD6G/MPP7/PRKCI	10
BP	GO:0046782	regulation of viral transcription	10/1616	64/18670	0.04737	0.4169	0.3866	CCNT1/TAF11/SMARCB1/POLR2D/POLR2H/TRIM11/IFITM3/RSF1/EP300/ZNF639	10
BP	GO:0046834	lipid phosphorylation	10/1616	64/18670	0.04737	0.4169	0.3866	CISH/PI4KAP1/SOCS3/PIK3R1/PIK3CA/SOCS2/IP6K1/IMPAD1/BPNT1/SOCS5	10
BP	GO:0030488	tRNA methylation	7/1616	39/18670	0.04768	0.4169	0.3866	TRMT112/TRMT10C/TRMT5/TRMT13/ALKBH8/NSUN2/THUMPD2	7
BP	GO:0031062	positive regulation of histone methylation	7/1616	39/18670	0.04768	0.4169	0.3866	PHF1/JARID2/BRD4/MECP2/WDR61/TET1/SIRT1	7
BP	GO:0038179	neurotrophin signaling pathway	7/1616	39/18670	0.04768	0.4169	0.3866	FRS2/AKT1S1/SOS1/RAPGEF2/DOK5/CORO1A/RAF1	7
BP	GO:0050856	regulation of T cell receptor signaling pathway	7/1616	39/18670	0.04768	0.4169	0.3866	PTPN6/GBP1/KCNN4/CEACAM1/BCL10/ELF1/UBASH3A	7
BP	GO:0060969	negative regulation of gene silencing	7/1616	39/18670	0.04768	0.4169	0.3866	ZC3H12A/NEAT1/ELAVL1/ZC3H10/AICDA/PHF2/TET1	7
BP	GO:0051168	nuclear export	24/1616	194/18670	0.04786	0.4169	0.3866	CTDSPL2/NUP50/CDK5/POLR2D/STRADB/DDX19B/TCF7L2/ENY2/NUP133/PARK7/AAAS/NUP35/SMURF1/SRSF11/XPO4/SLU7/AKAP8L/SRRM1/HNRNPA1/CSE1L/TSC1/PPM1A/WDR33/UPF1	24
BP	GO:0002478	antigen processing and presentation of exogenous peptide antigen	22/1616	175/18670	0.04864	0.4169	0.3866	IKBKB/DCTN4/TRAF6/KIF22/SNAP23/PSME2/AP2S1/DNM2/PSMD5/TAP1/CAPZB/PSMA5/IFI30/PSMA2/HLA-H/PSME4/DYNC1LI2/HLA-A/PSMB3/DYNLL1/HLA-C/PSMD2	22
BP	GO:0050684	regulation of mRNA processing	18/1616	137/18670	0.04884	0.4169	0.3866	CCNT1/MBNL2/PTBP1/RBM25/WTAP/METTL16/RBM19/RBM4B/ZFP36L1/RBM4/ZC3H10/RBM3/SRSF10/SAFB2/HNRNPL/HNRNPA1/KHDRBS3/RBM17	18
BP	GO:0010918	positive regulation of mitochondrial membrane potential	3/1616	10/18670	0.04893	0.4169	0.3866	BID/CTNS/VCP	3
BP	GO:0031848	protection from non-homologous end joining at telomere	3/1616	10/18670	0.04893	0.4169	0.3866	TERF2IP/XRCC1/ACD	3
BP	GO:0032070	regulation of deoxyribonuclease activity	3/1616	10/18670	0.04893	0.4169	0.3866	DFFA/DDX11/SIRT1	3
BP	GO:0035247	peptidyl-arginine omega-N-methylation	3/1616	10/18670	0.04893	0.4169	0.3866	PRMT1/CARM1/PRMT2	3
BP	GO:0035520	monoubiquitinated protein deubiquitination	3/1616	10/18670	0.04893	0.4169	0.3866	ASXL1/BAP1/USP16	3
BP	GO:0035999	tetrahydrofolate interconversion	3/1616	10/18670	0.04893	0.4169	0.3866	MTHFS/MTHFD2L/MTHFD1L	3
BP	GO:0042989	sequestering of actin monomers	3/1616	10/18670	0.04893	0.4169	0.3866	TWF2/TWF1/TMSB4Y	3
BP	GO:0043379	memory T cell differentiation	3/1616	10/18670	0.04893	0.4169	0.3866	CD46/TSC1/BCL6	3
BP	GO:0044351	macropinocytosis	3/1616	10/18670	0.04893	0.4169	0.3866	PYCARD/MAPKAPK3/DNM2	3
BP	GO:0052646	alditol phosphate metabolic process	3/1616	10/18670	0.04893	0.4169	0.3866	GPAM/ABHD6/GK	3
BP	GO:0060346	bone trabecula formation	3/1616	10/18670	0.04893	0.4169	0.3866	THBS3/WNT10B/COL1A1	3
BP	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain	3/1616	10/18670	0.04893	0.4169	0.3866	GTF2H5/GTF2H4/BRD4	3
BP	GO:0090715	immunological memory formation process	3/1616	10/18670	0.04893	0.4169	0.3866	CD46/TSC1/BCL6	3
BP	GO:1903332	regulation of protein folding	3/1616	10/18670	0.04893	0.4169	0.3866	PDCD5/GRN/SGTB	3
BP	GO:1903862	positive regulation of oxidative phosphorylation	3/1616	10/18670	0.04893	0.4169	0.3866	PARK7/PGK2/VCP	3
BP	GO:1904350	regulation of protein catabolic process in the vacuole	3/1616	10/18670	0.04893	0.4169	0.3866	GBA/MGAT3/ATP13A2	3
BP	GO:2000317	negative regulation of T-helper 17 type immune response	3/1616	10/18670	0.04893	0.4169	0.3866	ZC3H12A/IL27RA/RC3H2	3
BP	GO:2001214	positive regulation of vasculogenesis	3/1616	10/18670	0.04893	0.4169	0.3866	HIF1AN/CEACAM1/RAPGEF2	3
BP	GO:0016573	histone acetylation	20/1616	156/18670	0.04902	0.417	0.3867	PER1/SMARCB1/CREBBP/MORF4L1/MAP3K7/ACTL6A/ING5/KAT7/MBIP/TWIST1/KANSL2/BRPF1/RSF1/GTF3C4/EP300/PHF20/MECP2/BRD1/TADA1/SIRT1	20
BP	GO:0120034	positive regulation of plasma membrane bounded cell projection assembly	14/1616	100/18670	0.04909	0.417	0.3867	RAC2/SRF/CENPJ/ZMYND8/DNM2/P2RY12/TWF2/EPS8L2/ARAP1/CCDC88A/WASL/DYNLL1/HTT/NCKAP1	14
BP	GO:0009161	ribonucleoside monophosphate metabolic process	40/1616	354/18670	0.04946	0.4195	0.389	NUP50/NDUFS7/GART/HK1/AMPD2/NDUFS2/PGAM4/NDUFA12/RFK/PRKAG2/NUDT9/NUP133/NDUFB8/NUDT4/PARK7/AAAS/HSPA1A/BID/NUP35/VPS9D1/PFKFB3/NDUFB11/GALK1/NDUFB2/PGK2/HK2/MECP2/CTNS/PFKL/DHODH/VCP/NDUFB10/CAD/FOXK2/COQ9/PFKFB4/PFKP/DLD/ENTPD5/AK3	40
BP	GO:1903708	positive regulation of hemopoiesis	23/1616	185/18670	0.04953	0.4195	0.3891	CD83/PRMT1/ROR2/ZBTB1/IL34/ATXN1L/ISG15/TRAF6/HAX1/CD27/ACVR1B/FADD/HSPA1A/ZFP36L1/MMP14/IL12A/LGALS9/ZNF16/CD46/BCL6/PNP/SOCS5/TGFBR2	23
BP	GO:0010639	negative regulation of organelle organization	44/1616	395/18670	0.0499	0.4199	0.3895	PHF1/PHF23/SMARCB1/TERF2IP/CAMSAP3/PRELID1/HIP1R/MUL1/INSIG1/DUSP1/SWAP70/PRRT2/XRCC1/FKBP4/ACD/RBM14/MNAT1/GMFB/DNM2/SMCR8/BMP4/TWIST1/HSPA1A/TWF2/BNIP3/BCL2L1/CAPZB/CORO1B/AICDA/DCP2/TNKS/JARID2/TBC1D30/TWF1/ARAP1/TMSB4Y/CORO1A/GPX1/FNIP1/TNKS2/PHF2/HNRNPA1/TET1/SIRT1	44
BP	GO:0001912	positive regulation of leukocyte mediated cytotoxicity	9/1616	56/18670	0.04995	0.4199	0.3895	VAV1/FADD/IL18RAP/IL12A/MICA/HLA-H/MICB/HLA-A/HLA-C	9
BP	GO:0010332	response to gamma radiation	9/1616	56/18670	0.04995	0.4199	0.3895	GTF2H5/CHEK2/MEN1/POLB/TLK2/MYC/BCL2L1/GPX1/CDKN1A	9
BP	GO:0065002	intracellular protein transmembrane transport	9/1616	56/18670	0.04995	0.4199	0.3895	PEX12/GRPEL1/CHCHD4/PEX6/TOMM20L/PEX16/TIMM13/TIMM10/SEC61A2	9
BP	GO:1905515	non-motile cilium assembly	9/1616	56/18670	0.04995	0.4199	0.3895	GORAB/TMEM107/CENPJ/DNM2/CSNK1D/IFT122/DYNLL1/MKS1/IFT57	9
BP	GO:0006475	internal protein amino acid acetylation	21/1616	166/18670	0.05022	0.421	0.3905	PER1/SMARCB1/CREBBP/MORF4L1/MAP3K7/ACTL6A/ING5/KAT7/MBIP/TWIST1/KANSL2/BRPF1/RSF1/ATAT1/GTF3C4/EP300/PHF20/MECP2/BRD1/TADA1/SIRT1	21
BP	GO:2000377	regulation of reactive oxygen species metabolic process	24/1616	195/18670	0.05028	0.421	0.3905	RAC2/ZC3H12A/NOXA1/DDAH2/NFE2L2/THBS1/GCH1/MPV17/ACP5/PARK7/DHFR/DNM2/KLF4/BNIP3/GADD45A/HK2/CTNS/COQ7/BCO2/ASS1/SIRT5/CDKN1A/FBLN5/TGFBR2	24
BP	GO:0050863	regulation of T cell activation	36/1616	314/18670	0.05029	0.421	0.3905	CD83/PTPN6/RAC2/SIT1/ZBTB1/YES1/PRELID1/LAT/ZC3H12A/PYCARD/TRAF6/CSK/PIK3R1/CEACAM1/PIK3CA/CD27/VAV1/BCL10/FADD/BMP4/IL12A/SOS1/LGALS9/GLMN/CD46/TNFAIP8L2/CORO1A/RC3H2/GNRH1/JAK3/ADORA2A/BCL6/PNP/BTLA/SOCS5/TGFBR2	36
BP	GO:0002262	myeloid cell homeostasis	19/1616	147/18670	0.05044	0.421	0.3905	PRMT1/SRF/ERCC2/ISG15/IREB2/L3MBTL3/ACVR1B/BMP4/HSPA1A/SLC25A38/ZFP36L1/FANCC/SH2B3/THRA/ZNF16/JAK3/BAP1/BCL6/SLC11A2	19
BP	GO:0090263	positive regulation of canonical Wnt signaling pathway	19/1616	147/18670	0.05044	0.421	0.3905	ROR2/FRAT1/PSME2/CSNK1E/CSNK1D/PSMD5/PSMA5/TNKS/PSMA2/PSME4/FGF9/WNT10B/TNKS2/VCP/COL1A1/DKK2/PPM1A/PSMB3/PSMD2	19
BP	GO:0009123	nucleoside monophosphate metabolic process	42/1616	375/18670	0.05062	0.4219	0.3913	NUP50/NDUFS7/GART/HK1/AMPD2/DTYMK/NDUFS2/PGAM4/NDUFA12/RFK/PRKAG2/NUDT9/NUP133/NDUFB8/NUDT4/PARK7/AAAS/HSPA1A/BID/NUP35/VPS9D1/PFKFB3/NDUFB11/GALK1/NDUFB2/PGK2/HK2/MECP2/CTNS/PFKL/DHODH/VCP/NDUFB10/CAD/FOXK2/COQ9/PFKFB4/PFKP/DLD/NT5C1A/ENTPD5/AK3	42
BP	GO:0042866	pyruvate biosynthetic process	16/1616	119/18670	0.05103	0.4221	0.3914	NUP50/HK1/PGAM4/PRKAG2/NUP133/AAAS/NUP35/PFKFB3/GALK1/PGK2/HK2/PFKL/FOXK2/PFKFB4/PFKP/ENTPD5	16
BP	GO:0009110	vitamin biosynthetic process	5/1616	24/18670	0.0513	0.4221	0.3914	PSAT1/MMACHC/RFK/PNPO/GFI1	5
BP	GO:0046639	negative regulation of alpha-beta T cell differentiation	5/1616	24/18670	0.0513	0.4221	0.3914	ZC3H12A/RC3H2/JAK3/BCL6/SOCS5	5
BP	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process	5/1616	24/18670	0.0513	0.4221	0.3914	SULT2B1/IMPAD1/BPNT1/SULT1B1/SLC26A2	5
BP	GO:2000209	regulation of anoikis	5/1616	24/18670	0.0513	0.4221	0.3914	NOTCH1/CHEK2/SIK1/PIK3CA/ANKRD13C	5
BP	GO:0009135	purine nucleoside diphosphate metabolic process	18/1616	138/18670	0.05182	0.4221	0.3914	NUP50/HK1/PGAM4/PRKAG2/NUDT9/NUP133/AAAS/NUP35/PFKFB3/GALK1/PGK2/HK2/PFKL/FOXK2/PFKFB4/PFKP/ENTPD5/AK3	18
BP	GO:0009179	purine ribonucleoside diphosphate metabolic process	18/1616	138/18670	0.05182	0.4221	0.3914	NUP50/HK1/PGAM4/PRKAG2/NUDT9/NUP133/AAAS/NUP35/PFKFB3/GALK1/PGK2/HK2/PFKL/FOXK2/PFKFB4/PFKP/ENTPD5/AK3	18
BP	GO:0031060	regulation of histone methylation	10/1616	65/18670	0.05182	0.4221	0.3914	PHF1/SMARCB1/ZNF274/JARID2/BRD4/MECP2/WDR61/TET1/GFI1/SIRT1	10
BP	GO:0002697	regulation of immune effector process	50/1616	458/18670	0.05211	0.4221	0.3914	PTPN6/RAC2/PHB/HK1/ZBTB1/PPM1B/ZC3H12A/PYCARD/IFIT1/TRAF6/TNFAIP3/RSAD2/ANKRD17/MUL1/DTX3L/SUSD4/MAP3K7/CEACAM1/GRN/VAV1/BCL10/FADD/VTN/IL18RAP/BST2/ZCCHC3/IL12A/RNF26/ATAD5/GPATCH3/LGALS9/CLCF1/RNF125/CD46/MICA/IL27RA/HLA-H/MICB/PQBP1/RC3H2/JAK3/HLA-A/EIF2AK4/BCL6/DDX58/TSPAN32/HLA-C/SOCS5/C5/APOA1	50
BP	GO:0009069	serine family amino acid metabolic process	8/1616	48/18670	0.05216	0.4221	0.3914	PSAT1/SERINC3/GART/AHCY/PSPH/GCAT/SEPSECS/CTH	8
BP	GO:0030850	prostate gland development	8/1616	48/18670	0.05216	0.4221	0.3914	NOTCH1/FEM1B/FKBP4/CDKN1B/FRS2/BMP4/TP63/UBE3A	8
BP	GO:0044764	multi-organism cellular process	8/1616	48/18670	0.05216	0.4221	0.3914	IRF7/CXCR4/ANKRD17/ZCCHC3/GPATCH3/RNF125/FCHSD1/DDX58	8
BP	GO:1990542	mitochondrial transmembrane transport	14/1616	101/18670	0.05265	0.4221	0.3914	CPT1B/GRPEL1/MRS2/CHCHD4/TOMM20L/PRKAG2/SLC25A20/SLC25A28/SLC25A36/TIMM13/SLC25A38/UCP2/TIMM10/MPC1	14
BP	GO:0010389	regulation of G2/M transition of mitotic cell cycle	24/1616	196/18670	0.0528	0.4221	0.3914	CDK4/FOXN3/ZNF830/CENPJ/PSME2/ODF2/CSNK1E/SFI1/CSNK1D/PSMD5/PSMA5/KIF14/PSMA2/PSME4/BRD4/MECP2/WNT10B/NDE1/CDC25B/PSMB3/DYNLL1/GPR132/HAUS2/PSMD2	24
BP	GO:0009064	glutamine family amino acid metabolic process	11/1616	74/18670	0.05283	0.4221	0.3914	MTHFS/AMDHD1/DDAH2/GFPT2/NOS3/ALDH4A1/ALDH18A1/MECP2/FAH/CAD/ASS1	11
BP	GO:0035148	tube formation	19/1616	148/18670	0.05337	0.4221	0.3914	NOTCH1/SEMA4C/FZD6/TRAF6/BCL10/DICER1/BMP4/TWIST1/VASP/GLMN/CFL1/IFT122/TSC1/MTHFD1L/ALX1/CTHRC1/NPHP3/MKS1/IFT57	19
BP	GO:0006744	ubiquinone biosynthetic process	4/1616	17/18670	0.05348	0.4221	0.3914	COQ10B/COQ7/COQ9/PPTC7	4
BP	GO:0006825	copper ion transport	4/1616	17/18670	0.05348	0.4221	0.3914	SCO1/FKBP4/SCO2/SLC11A2	4
BP	GO:0007076	mitotic chromosome condensation	4/1616	17/18670	0.05348	0.4221	0.3914	AKAP8/NCAPD2/PHF23/AKAP8L	4
BP	GO:0009070	serine family amino acid biosynthetic process	4/1616	17/18670	0.05348	0.4221	0.3914	PSAT1/SERINC3/PSPH/CTH	4
BP	GO:0010224	response to UV-B	4/1616	17/18670	0.05348	0.4221	0.3914	HYAL3/IL12A/MFAP4/CDKN1A	4
BP	GO:0016246	RNA interference	4/1616	17/18670	0.05348	0.4221	0.3914	CLP1/DICER1/MRPL44/TSN	4
BP	GO:0031000	response to caffeine	4/1616	17/18670	0.05348	0.4221	0.3914	HDAC2/DHODH/CAD/ADORA2A	4
BP	GO:0033262	regulation of nuclear cell cycle DNA replication	4/1616	17/18670	0.05348	0.4221	0.3914	CHEK2/DBF4/AICDA/BCL6	4
BP	GO:0036270	response to diuretic	4/1616	17/18670	0.05348	0.4221	0.3914	HDAC2/DHODH/CAD/ADORA2A	4
BP	GO:0046500	S-adenosylmethionine metabolic process	4/1616	17/18670	0.05348	0.4221	0.3914	MAT2B/AHCY/METTL16/MAT2A	4
BP	GO:0055070	copper ion homeostasis	4/1616	17/18670	0.05348	0.4221	0.3914	SCO1/SCO2/CCDC22/COX19	4
BP	GO:0060263	regulation of respiratory burst	4/1616	17/18670	0.05348	0.4221	0.3914	RAC2/NOXA1/GRN/CAMK1D	4
BP	GO:0071850	mitotic cell cycle arrest	4/1616	17/18670	0.05348	0.4221	0.3914	DUSP1/CDKN1B/GADD45A/CDKN1A	4
BP	GO:1901663	quinone biosynthetic process	4/1616	17/18670	0.05348	0.4221	0.3914	COQ10B/COQ7/COQ9/PPTC7	4
BP	GO:2000001	regulation of DNA damage checkpoint	4/1616	17/18670	0.05348	0.4221	0.3914	FEM1B/CHEK2/RPA2/ETAA1	4
BP	GO:2000136	regulation of cell proliferation involved in heart morphogenesis	4/1616	17/18670	0.05348	0.4221	0.3914	PIM1/NOTCH1/BMP4/MKS1	4
BP	GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	7/1616	40/18670	0.05365	0.4221	0.3914	PTPN6/ZC3H12A/CEACAM1/IL27RA/RC3H2/JAK3/BCL6	7
BP	GO:0021532	neural tube patterning	7/1616	40/18670	0.05365	0.4221	0.3914	GORAB/TMEM107/BMP4/IFT122/GPR161/GSC/MKS1	7
BP	GO:0032008	positive regulation of TOR signaling	7/1616	40/18670	0.05365	0.4221	0.3914	PIK3CA/RICTOR/SMCR8/HTR6/WDR24/SLC38A9/LAMTOR2	7
BP	GO:0098760	response to interleukin-7	7/1616	40/18670	0.05365	0.4221	0.3914	CISH/STIP1/BRWD1/SOCS2/CRLF2/IRS2/JAK3	7
BP	GO:0098761	cellular response to interleukin-7	7/1616	40/18670	0.05365	0.4221	0.3914	CISH/STIP1/BRWD1/SOCS2/CRLF2/IRS2/JAK3	7
BP	GO:0006505	GPI anchor metabolic process	6/1616	32/18670	0.05377	0.4221	0.3914	PIGA/PIGH/MPPE1/PIGL/DPM1/GPAA1	6
BP	GO:0007616	long-term memory	6/1616	32/18670	0.05377	0.4221	0.3914	SRF/RGS14/BTBD9/MECP2/CTNS/EIF2AK4	6
BP	GO:0051085	chaperone cofactor-dependent protein refolding	6/1616	32/18670	0.05377	0.4221	0.3914	DNAJB5/HSPA1A/DNAJB1/HSPA1L/TOR2A/HSPA13	6
BP	GO:1901661	quinone metabolic process	6/1616	32/18670	0.05377	0.4221	0.3914	CBR4/COQ10B/AKR1C2/COQ7/COQ9/PPTC7	6
BP	GO:1902235	regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	6/1616	32/18670	0.05377	0.4221	0.3914	SERINC3/PARK7/HSPA1A/BCL2L1/HERPUD1/SIRT1	6
BP	GO:1903955	positive regulation of protein targeting to mitochondrion	6/1616	32/18670	0.05377	0.4221	0.3914	RAC2/PDCD5/SH3GLB1/GSK3A/BAP1/HSPA1L	6
BP	GO:0001818	negative regulation of cytokine production	34/1616	296/18670	0.05461	0.4281	0.397	CD83/PTPN6/GBP1/AKAP8/PPM1B/ISG15/ZC3H12A/PYCARD/CSK/TNFAIP3/ASB1/THBS1/MUL1/CEACAM1/REL/ACP5/C1QTNF3/DICER1/GBA/TWIST1/KLF4/BST2/IL12A/HOMER2/GPATCH3/LGALS9/RNF125/IL27RA/GATA6/JAK3/BCL6/DDX58/SOCS5/APOA1	34
BP	GO:1905475	regulation of protein localization to membrane	23/1616	187/18670	0.05473	0.4285	0.3974	GBP1/CDK5/CSK/NMT1/PDCD5/PIK3R1/ACTB/ZMYND8/BID/BCL2L1/MMP14/RAB11FIP2/ITGA3/PRKCE/RANGRF/YWHAZ/ACSL3/GRASP/IQSEC2/TFDP2/TP63/PRKCI/PDZK1	23
BP	GO:2000272	negative regulation of signaling receptor activity	9/1616	57/18670	0.05495	0.4296	0.3984	SOCS4/TSG101/CBLB/DKK4/DKK2/MTRNR2L5/ZGPAT/IL18BP/SOCS5	9
BP	GO:0009156	ribonucleoside monophosphate biosynthetic process	24/1616	197/18670	0.0554	0.4322	0.4008	NUP50/GART/HK1/AMPD2/PGAM4/RFK/PRKAG2/NUP133/AAAS/NUP35/VPS9D1/PFKFB3/GALK1/PGK2/HK2/PFKL/DHODH/VCP/CAD/FOXK2/PFKFB4/PFKP/ENTPD5/AK3	24
BP	GO:0051052	regulation of DNA metabolic process	47/1616	429/18670	0.05543	0.4322	0.4008	CCT5/ENDOG/CHTF8/STAG2/EHMT2/ERCC2/TERF2IP/CHEK2/MEN1/ZNF830/DBF4/ANKRD17/DUSP1/DFFA/CCT6A/DTX3L/PIK3CA/XRCC1/ACD/NUDT16L1/MYC/SPIRE2/TWIST1/TSPYL2/RPA2/KLF4/RMI2/AICDA/DCP2/OTUD4/ATAD5/TNKS/SENP2/CLCF1/IL27RA/MBD1/MECP2/CCDC88A/TNKS2/HNRNPA1/DDX11/UPF1/BCL6/TET1/MAPT-AS1/CDKN1A/SIRT1	47
BP	GO:0043405	regulation of MAP kinase activity	38/1616	337/18670	0.05572	0.4338	0.4024	AVPI1/PTPN6/DUSP8/ROR2/RGS14/CXCR4/TRAF6/CSK/MAPKAPK3/THBS1/MUL1/DUSP1/TRIB3/MAP3K7/MAP3K3/MAP3K14/PDCD10/PDE6G/MAPK11/MBIP/FRS2/BMP4/GBA/SH2B3/GADD45A/TSG101/ADAM9/MST1R/LPAR3/MAPK8IP3/PPEF2/DNAJA1/RAF1/DAXX/DUSP7/C5/LAMTOR2/PDGFC	38
BP	GO:0006643	membrane lipid metabolic process	25/1616	207/18670	0.05593	0.4343	0.4028	ESYT2/SERINC3/PIGA/KDSR/ST6GALNAC4/ORMDL2/NAGA/ST3GAL5/SAMD8/ST3GAL2/CTSA/GBA/GALC/ASAH2B/SERINC1/B4GALT4/PLA2G15/SMPD4/PIGH/GM2A/MPPE1/PIGL/DPM1/SPTLC2/GPAA1	25
BP	GO:0070555	response to interleukin-1	25/1616	207/18670	0.05593	0.4343	0.4028	PELI2/GBP1/NFKBIA/IKBKB/HYAL3/ZC3H12A/PYCARD/TRAF6/MAP3K7/MAP3K3/PSME2/PLCB1/RORA/MAPK11/PSMD5/PSMA5/OTUD4/LGALS9/PSMA2/NR1D1/PSME4/UPF1/PSMB3/PRKCI/PSMD2	25
BP	GO:0002367	cytokine production involved in immune response	14/1616	102/18670	0.05638	0.4372	0.4055	MR1/HK1/TRAF6/RSAD2/MAP3K7/BCL10/IL18RAP/BST2/IL12A/JAK3/BCL6/DDX58/APOA1/SIRT1	14
BP	GO:1901607	alpha-amino acid biosynthetic process	10/1616	66/18670	0.05655	0.4379	0.4062	PSAT1/SERINC3/BCAT1/PSPH/PARK7/MTHFD2L/ALDH18A1/CAD/ASS1/CTH	10
BP	GO:0006457	protein folding	27/1616	227/18670	0.05666	0.4382	0.4064	CCT5/MPDU1/DNAJC21/LMAN2L/GRPEL1/DNAJB5/PDCD5/CHCHD4/DFFA/CCT6A/GRN/FKBP4/HSPA1A/EMC6/DNAJB1/SGTB/PDRG1/PPIL1/VBP1/PFDN6/UNC45A/VCP/DNAJA1/HSPA1L/TOR2A/HSPA13/ENTPD5	27
BP	GO:0097237	cellular response to toxic substance	29/1616	247/18670	0.05702	0.4404	0.4084	ENDOG/ZC3H12A/TNFAIP3/NFE2L2/PRDX3/PRDX5/PDCD10/GCH1/ACTB/PARK7/DHFR/DNM2/TXNDC17/NOS3/KLF4/BNIP3/HDAC2/IL18RAP/FANCC/PTGS1/PRKCE/APOM/SIGMAR1/GPX1/HNRNPA1/DDX11/DAXX/SIRT1/FBLN5	29
BP	GO:0048863	stem cell differentiation	30/1616	257/18670	0.05709	0.4404	0.4084	PDCD6/NOTCH1/SRF/ERCC2/SEMA4C/BATF/ZNF281/KBTBD8/NFE2L2/CHD2/ASCL1/PSME2/SEMA4F/BMP4/TWIST1/PSMD5/PSMA5/CFL1/JARID2/PSMA2/GATA6/ZFP36L2/PSME4/ALX1/PSMB3/TP63/MEOX1/MSI2/GSC/PSMD2	30
BP	GO:0006368	transcription elongation from RNA polymerase II promoter	12/1616	84/18670	0.0574	0.4416	0.4095	CCNT1/GTF2H5/ERCC2/POLR2D/POLR2H/MNAT1/ENY2/EAF1/GTF2H4/BRD4/WDR61/ELL2	12
BP	GO:1905897	regulation of response to endoplasmic reticulum stress	12/1616	84/18670	0.0574	0.4416	0.4095	SERINC3/NFE2L2/PIK3R1/BFAR/PPP1R15B/PARK7/HSPA1A/DNAJB9/BCL2L1/HERPUD1/YOD1/SIRT1	12
BP	GO:0032757	positive regulation of interleukin-8 production	8/1616	49/18670	0.05782	0.4442	0.412	PYCARD/TLR5/PARK7/BCL10/FADD/HSPA1A/LGALS9/DDX58	8
BP	GO:0009185	ribonucleoside diphosphate metabolic process	18/1616	140/18670	0.05815	0.4462	0.4138	NUP50/HK1/PGAM4/PRKAG2/NUDT9/NUP133/AAAS/NUP35/PFKFB3/GALK1/PGK2/HK2/PFKL/FOXK2/PFKFB4/PFKP/ENTPD5/AK3	18
BP	GO:0006354	DNA-templated transcription, elongation	15/1616	112/18670	0.05914	0.4488	0.4162	CD3EAP/CCNT1/GTF2H5/ERCC2/POLR2D/POLR2H/TSFM/MNAT1/ENY2/SCAF8/EAF1/GTF2H4/BRD4/WDR61/ELL2	15
BP	GO:0008645	hexose transmembrane transport	15/1616	112/18670	0.05914	0.4488	0.4162	SLC5A3/YES1/ADIPOR2/NFE2L2/TRIB3/PIK3R1/PRKAG2/GSK3A/SLC2A1/SLC50A1/HK2/IRS2/TSC1/PRKCI/SLC2A9	15
BP	GO:0042303	molting cycle	15/1616	112/18670	0.05914	0.4488	0.4162	PER1/GORAB/NOTCH1/ERCC2/FZD6/TMEM79/KRTAP4-5/ACVR1B/HDAC2/SOS1/DKK4/WNT10B/KRT17/TP63/NSUN2	15
BP	GO:0042633	hair cycle	15/1616	112/18670	0.05914	0.4488	0.4162	PER1/GORAB/NOTCH1/ERCC2/FZD6/TMEM79/KRTAP4-5/ACVR1B/HDAC2/SOS1/DKK4/WNT10B/KRT17/TP63/NSUN2	15
BP	GO:0043279	response to alkaloid	15/1616	112/18670	0.05914	0.4488	0.4162	CDK5/CXCR4/DNM2/FADD/HDAC2/BCL2L1/HOMER2/PRKCE/MBD1/DHODH/CAD/MTRNR2L5/UBE3A/ADORA2A/CASP7	15
BP	GO:0042180	cellular ketone metabolic process	29/1616	248/18670	0.05946	0.4488	0.4162	KDSR/ALDH8A1/NMT1/ADIPOR2/INSIG1/TRIB3/CEACAM1/PRKAG2/PSME2/CBR4/COQ10B/PARK7/TWIST1/PSMD5/PSMA5/PRKCE/PSMA2/DHRS4/AKR1C2/NR1D1/PSME4/IRS2/COQ7/COQ9/PSMB3/PPTC7/SIRT5/PSMD2/SIRT1	29
BP	GO:0030177	positive regulation of Wnt signaling pathway	22/1616	179/18670	0.05961	0.4488	0.4162	ROR2/FRAT1/ZRANB1/TNFAIP3/PSME2/DIXDC1/CSNK1E/CSNK1D/PSMD5/PSMA5/TNKS/PSMA2/PSME4/FGF9/WNT10B/TNKS2/VCP/COL1A1/DKK2/PPM1A/PSMB3/PSMD2	22
BP	GO:0002507	tolerance induction	5/1616	25/18670	0.05974	0.4488	0.4162	TNFAIP3/AIRE/LGALS9/PHLPP1/TGFBR2	5
BP	GO:0003309	type B pancreatic cell differentiation	5/1616	25/18670	0.05974	0.4488	0.4162	MEN1/GSK3A/BMP4/GATA6/RFX3	5
BP	GO:0031069	hair follicle morphogenesis	5/1616	25/18670	0.05974	0.4488	0.4162	GORAB/NOTCH1/TMEM79/KRT17/TP63	5
BP	GO:0032438	melanosome organization	5/1616	25/18670	0.05974	0.4488	0.4162	BLOC1S5/TRAPPC6A/SNAPIN/BLOC1S4/KIF13A	5
BP	GO:0034035	purine ribonucleoside bisphosphate metabolic process	5/1616	25/18670	0.05974	0.4488	0.4162	SULT2B1/IMPAD1/BPNT1/SULT1B1/SLC26A2	5
BP	GO:2000679	positive regulation of transcription regulatory region DNA binding	5/1616	25/18670	0.05974	0.4488	0.4162	TRAF6/PARK7/TWIST1/KLF4/EP300	5
BP	GO:0055076	transition metal ion homeostasis	17/1616	131/18670	0.05983	0.4488	0.4162	SLC39A14/HMOX2/SCO1/IREB2/MYC/SRI/SCO2/SLC25A28/SLC30A1/BTBD9/CCDC22/COX19/TMEM199/ATP6V1G1/SLC30A5/ATP13A2/SLC11A2	17
BP	GO:0030520	intracellular estrogen receptor signaling pathway	9/1616	58/18670	0.06028	0.4488	0.4162	EGLN2/CARM1/PAGR1/RBM14/GPAM/DDX54/SKP2/TP63/UFM1	9
BP	GO:0061951	establishment of protein localization to plasma membrane	9/1616	58/18670	0.06028	0.4488	0.4162	GOLPH3L/CSK/SYS1/NSG1/GORASP1/ACSL3/GRASP/RAB10/KIF13A	9
BP	GO:0019362	pyridine nucleotide metabolic process	23/1616	189/18670	0.06031	0.4488	0.4162	NUP50/PARP10/HK1/PGAM4/PDHA1/PRKAG2/TALDO1/NUP133/ASPDH/AAAS/NUP35/PFKFB3/GALK1/PGK2/HK2/PFKL/VCP/FOXK2/PFKFB4/PFKP/DLD/MPC1/ENTPD5	23
BP	GO:0046496	nicotinamide nucleotide metabolic process	23/1616	189/18670	0.06031	0.4488	0.4162	NUP50/PARP10/HK1/PGAM4/PDHA1/PRKAG2/TALDO1/NUP133/ASPDH/AAAS/NUP35/PFKFB3/GALK1/PGK2/HK2/PFKL/VCP/FOXK2/PFKFB4/PFKP/DLD/MPC1/ENTPD5	23
BP	GO:0001914	regulation of T cell mediated cytotoxicity	6/1616	33/18670	0.06111	0.4488	0.4162	CEACAM1/FADD/IL12A/HLA-H/HLA-A/HLA-C	6
BP	GO:0006370	7-methylguanosine mRNA capping	6/1616	33/18670	0.06111	0.4488	0.4162	GTF2H5/ERCC2/POLR2D/POLR2H/MNAT1/GTF2H4	6
BP	GO:0009303	rRNA transcription	6/1616	33/18670	0.06111	0.4488	0.4162	CD3EAP/GTF3A/SMARCB1/BRF1/GTF3C4/DDX11	6
BP	GO:0048536	spleen development	6/1616	33/18670	0.06111	0.4488	0.4162	POLB/CDKN2B/FADD/NFKB2/JARID2/RC3H2	6
BP	GO:0048821	erythrocyte development	6/1616	33/18670	0.06111	0.4488	0.4162	SRF/ERCC2/L3MBTL3/SH2B3/BCL6/SLC11A2	6
BP	GO:0051204	protein insertion into mitochondrial membrane	6/1616	33/18670	0.06111	0.4488	0.4162	MOAP1/NMT1/BID/YWHAZ/TFDP2/TP63	6
BP	GO:0019748	secondary metabolic process	10/1616	67/18670	0.06155	0.4488	0.4162	AKR7A3/NFE2L2/CBR4/CYP2D6/ETHE1/RAPGEF2/AKR1C2/DDT/CTNS/CTH	10
BP	GO:1901532	regulation of hematopoietic progenitor cell differentiation	12/1616	85/18670	0.06181	0.4488	0.4162	NOTCH1/ZBTB1/NFE2L2/PSME2/PSMD5/PSMA5/SOS1/PSMA2/PSME4/FNIP1/PSMB3/PSMD2	12
BP	GO:0051402	neuron apoptotic process	28/1616	239/18670	0.06193	0.4488	0.4162	EGLN2/CDK5/EGLN3/NR4A2/CASP9/POLB/GRN/ASCL1/PIK3CA/PARK7/FADD/AKT1S1/BID/BTG2/AGAP2/BNIP3/BCL2L1/KIF14/CLCF1/FAIM2/TRIM2/ATF4/CORO1A/MECP2/SIGMAR1/TP63/ADORA2A/PRKCI	28
BP	GO:0046785	microtubule polymerization	11/1616	76/18670	0.06198	0.4488	0.4162	CAMSAP3/CENPJ/TPPP3/FKBP4/CDKN1B/HSPA1A/CSNK1D/RANGRF/MECP2/NDE1/TUBGCP5	11
BP	GO:0051235	maintenance of location	37/1616	330/18670	0.06241	0.4488	0.4162	PTPN6/MXI1/NFKBIE/HK1/NFKBIA/CDK5/PLCH2/GET4/CAMK2D/ZC3H12A/TOPORS/PNPLA2/INSIG1/PLCB1/ATP2A1/FITM1/SRI/PARK7/BSCL2/CHERP/TWF2/CCDC22/G3BP2/GM2A/PRKCE/FTO/TWF1/TMSB4Y/HK2/CORO1A/SPAG4/ANKRD13C/GPSM2/HTT/APOA1/SIRT1/GPAA1	37
BP	GO:0016999	antibiotic metabolic process	19/1616	151/18670	0.0629	0.4488	0.4162	RAC2/NAGK/ST6GAL1/MTHFS/NOXA1/AMDHD1/PDHA1/PRDX3/PRDX5/IREB2/CBR4/GNPDA1/PARK7/AKR1C2/GPX1/CTNS/SULT1B1/MTHFD1L/DLD	19
BP	GO:0002223	stimulatory C-type lectin receptor signaling pathway	15/1616	113/18670	0.06299	0.4488	0.4162	IKBKB/TRAF6/CREBBP/MAP3K7/PSME2/BCL10/PSMD5/PSMA5/PSMA2/MUCL1/EP300/PSME4/PSMB3/RAF1/PSMD2	15
BP	GO:0000478	endonucleolytic cleavage involved in rRNA processing	3/1616	11/18670	0.06307	0.4488	0.4162	ABT1/NOL9/UTP23	3
BP	GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	3/1616	11/18670	0.06307	0.4488	0.4162	ABT1/NOL9/UTP23	3
BP	GO:0002328	pro-B cell differentiation	3/1616	11/18670	0.06307	0.4488	0.4162	NOTCH1/SOS1/FNIP1	3
BP	GO:0002517	T cell tolerance induction	3/1616	11/18670	0.06307	0.4488	0.4162	AIRE/PHLPP1/TGFBR2	3
BP	GO:0002730	regulation of dendritic cell cytokine production	3/1616	11/18670	0.06307	0.4488	0.4162	BST2/JAK3/DDX58	3
BP	GO:0003264	regulation of cardioblast proliferation	3/1616	11/18670	0.06307	0.4488	0.4162	PIM1/NOTCH1/MKS1	3
BP	GO:0006048	UDP-N-acetylglucosamine biosynthetic process	3/1616	11/18670	0.06307	0.4488	0.4162	NAGK/GNPDA1/GFPT2	3
BP	GO:0006054	N-acetylneuraminate metabolic process	3/1616	11/18670	0.06307	0.4488	0.4162	NAGK/ST6GAL1/GNPDA1	3
BP	GO:0006853	carnitine shuttle	3/1616	11/18670	0.06307	0.4488	0.4162	CPT1B/PRKAG2/SLC25A20	3
BP	GO:0009125	nucleoside monophosphate catabolic process	3/1616	11/18670	0.06307	0.4488	0.4162	NUDT9/NUDT4/NT5C1A	3
BP	GO:0010172	embryonic body morphogenesis	3/1616	11/18670	0.06307	0.4488	0.4162	ZNF281/IFT122/GREM2	3
BP	GO:0018202	peptidyl-histidine modification	3/1616	11/18670	0.06307	0.4488	0.4162	HIF1AN/DPH3P1/DPH2	3
BP	GO:0030422	production of siRNA involved in RNA interference	3/1616	11/18670	0.06307	0.4488	0.4162	DICER1/MRPL44/TSN	3
BP	GO:0033632	regulation of cell-cell adhesion mediated by integrin	3/1616	11/18670	0.06307	0.4488	0.4162	CXCL13/SWAP70/FERMT3	3
BP	GO:0035246	peptidyl-arginine N-methylation	3/1616	11/18670	0.06307	0.4488	0.4162	PRMT1/CARM1/PRMT2	3
BP	GO:0036462	TRAIL-activated apoptotic signaling pathway	3/1616	11/18670	0.06307	0.4488	0.4162	TNFRSF10B/PARK7/FADD	3
BP	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress	3/1616	11/18670	0.06307	0.4488	0.4162	NFE2L2/ATF4/CHD6	3
BP	GO:0046512	sphingosine biosynthetic process	3/1616	11/18670	0.06307	0.4488	0.4162	GBA/ASAH2B/SPTLC2	3
BP	GO:0051574	positive regulation of histone H3-K9 methylation	3/1616	11/18670	0.06307	0.4488	0.4162	JARID2/MECP2/SIRT1	3
BP	GO:0060433	bronchus development	3/1616	11/18670	0.06307	0.4488	0.4162	SRF/BMP4/TGFBR2	3
BP	GO:0060525	prostate glandular acinus development	3/1616	11/18670	0.06307	0.4488	0.4162	NOTCH1/FRS2/TP63	3
BP	GO:0060947	cardiac vascular smooth muscle cell differentiation	3/1616	11/18670	0.06307	0.4488	0.4162	NOTCH1/SRF/GATA6	3
BP	GO:0070213	protein auto-ADP-ribosylation	3/1616	11/18670	0.06307	0.4488	0.4162	PARP10/TNKS/TNKS2	3
BP	GO:0072608	interleukin-10 secretion	3/1616	11/18670	0.06307	0.4488	0.4162	ISG15/PYCARD/LGALS9	3
BP	GO:0072683	T cell extravasation	3/1616	11/18670	0.06307	0.4488	0.4162	FADD/IL27RA/CD99	3
BP	GO:1900102	negative regulation of endoplasmic reticulum unfolded protein response	3/1616	11/18670	0.06307	0.4488	0.4162	BFAR/PPP1R15B/DNAJB9	3
BP	GO:1901096	regulation of autophagosome maturation	3/1616	11/18670	0.06307	0.4488	0.4162	PHF23/SMCR8/IRGM	3
BP	GO:1905383	protein localization to presynapse	3/1616	11/18670	0.06307	0.4488	0.4162	MAPK8IP3/RAB27B/MAP1A	3
BP	GO:0072175	epithelial tube formation	17/1616	132/18670	0.06339	0.4488	0.4162	SEMA4C/FZD6/TRAF6/BCL10/BMP4/TWIST1/VASP/GLMN/CFL1/IFT122/TSC1/MTHFD1L/ALX1/CTHRC1/NPHP3/MKS1/IFT57	17
BP	GO:0042398	cellular modified amino acid biosynthetic process	8/1616	50/18670	0.06384	0.4488	0.4162	GART/MTHFS/NFE2L2/GCH1/CHAC2/PARK7/DHFR/MTHFD1L	8
BP	GO:0009126	purine nucleoside monophosphate metabolic process	38/1616	341/18670	0.06417	0.4488	0.4162	NUP50/NDUFS7/GART/HK1/AMPD2/NDUFS2/PGAM4/NDUFA12/PRKAG2/NUDT9/NUP133/NDUFB8/NUDT4/PARK7/AAAS/HSPA1A/BID/NUP35/VPS9D1/PFKFB3/NDUFB11/GALK1/NDUFB2/PGK2/HK2/MECP2/CTNS/PFKL/VCP/NDUFB10/FOXK2/COQ9/PFKFB4/PFKP/DLD/NT5C1A/ENTPD5/AK3	38
BP	GO:0002902	regulation of B cell apoptotic process	4/1616	18/18670	0.06422	0.4488	0.4162	BCL10/IRS2/FNIP1/BCL6	4
BP	GO:0006607	NLS-bearing protein import into nucleus	4/1616	18/18670	0.06422	0.4488	0.4162	KPNA5/NUP35/CBLB/RGPD6	4
BP	GO:0006743	ubiquinone metabolic process	4/1616	18/18670	0.06422	0.4488	0.4162	COQ10B/COQ7/COQ9/PPTC7	4
BP	GO:0009048	dosage compensation by inactivation of X chromosome	4/1616	18/18670	0.06422	0.4488	0.4162	EIF1/CDYL/UPF1/RLIM	4
BP	GO:0009200	deoxyribonucleoside triphosphate metabolic process	4/1616	18/18670	0.06422	0.4488	0.4162	DTYMK/NUDT1/TBPL1/DCTPP1	4
BP	GO:0009312	oligosaccharide biosynthetic process	4/1616	18/18670	0.06422	0.4488	0.4162	MPDU1/ST3GAL2/SLC2A1/ST6GALNAC1	4
BP	GO:0039535	regulation of RIG-I signaling pathway	4/1616	18/18670	0.06422	0.4488	0.4162	ANKRD17/ZCCHC3/GPATCH3/RNF125	4
BP	GO:0070230	positive regulation of lymphocyte apoptotic process	4/1616	18/18670	0.06422	0.4488	0.4162	PRELID1/LGALS14/LGALS9/FNIP1	4
BP	GO:0071605	monocyte chemotactic protein-1 production	4/1616	18/18670	0.06422	0.4488	0.4162	C1QTNF3/TWIST1/LGALS9/SOCS5	4
BP	GO:0071637	regulation of monocyte chemotactic protein-1 production	4/1616	18/18670	0.06422	0.4488	0.4162	C1QTNF3/TWIST1/LGALS9/SOCS5	4
BP	GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	4/1616	18/18670	0.06422	0.4488	0.4162	TNRC6B/BTG2/ZFP36L1/ZFP36L2	4
BP	GO:1904872	regulation of telomerase RNA localization to Cajal body	4/1616	18/18670	0.06422	0.4488	0.4162	CCT5/NOP10/CCT6A/DCP2	4
BP	GO:0030217	T cell differentiation	28/1616	240/18670	0.06457	0.4507	0.418	CD83/SRF/PATZ1/ZBTB1/BATF/PRELID1/ZC3H12A/RSAD2/RORA/CD27/VAV1/FADD/BMP4/ZFP36L1/IL12A/AIRE/SOS1/LGALS9/CD46/ZFP36L2/NHEJ1/RC3H2/JAK3/TSC1/BCL6/PNP/SOCS5/TGFBR2	28
BP	GO:0009141	nucleoside triphosphate metabolic process	40/1616	362/18670	0.06529	0.4551	0.4221	NUP50/NDUFS7/HK1/DTYMK/NDUFS2/PGAM4/NDUFA12/PRKAG2/NUP133/NDUFB8/PARK7/MBIP/AAAS/HSPA1A/BID/NUP35/NUDT1/TBPL1/VPS9D1/PFKFB3/NDUFB11/DCTPP1/GALK1/NDUFB2/PGK2/GTPBP1/HK2/MECP2/CTNS/PFKL/VCP/NDUFB10/CAD/FOXK2/COQ9/PFKFB4/PFKP/DLD/ENTPD5/AK3	40
BP	GO:0001836	release of cytochrome c from mitochondria	9/1616	59/18670	0.06592	0.4584	0.4251	MOAP1/PRELID1/PYCARD/PDCD5/TNFSF10/BID/BNIP3/BCL2L1/GPX1	9
BP	GO:0008333	endosome to lysosome transport	9/1616	59/18670	0.06592	0.4584	0.4251	SNX27/DTX3L/VPS18/M6PR/ATG14/SNAPIN/TSG101/VCP/KIF13A	9
BP	GO:0033044	regulation of chromosome organization	38/1616	342/18670	0.06642	0.4613	0.4279	CCT5/AKAP8/PARP10/PHF1/SMARCB1/TERF2IP/CAMK2D/MIER1/DUSP1/SFPQ/CCT6A/TLK2/XRCC1/ACD/MYC/MNAT1/KAT7/TWIST1/RMI2/AICDA/DCP2/TNKS/ZNF274/JARID2/RNF4/BRD4/AKAP8L/MECP2/TNKS2/PHF2/WDR61/HNRNPA1/DDX11/UPF1/BCL6/TET1/GFI1/SIRT1	38
BP	GO:0002703	regulation of leukocyte mediated immunity	24/1616	201/18670	0.06671	0.4628	0.4292	PTPN6/RAC2/ZBTB1/TRAF6/RSAD2/MAP3K7/CEACAM1/VAV1/FADD/IL18RAP/BST2/IL12A/ATAD5/LGALS9/CLCF1/MICA/IL27RA/HLA-H/MICB/JAK3/HLA-A/BCL6/DDX58/HLA-C	24
BP	GO:0002292	T cell differentiation involved in immune response	10/1616	68/18670	0.06682	0.4631	0.4295	BATF/ZC3H12A/RORA/LGALS9/CD46/RC3H2/JAK3/TSC1/BCL6/SOCS5	10
BP	GO:0006284	base-excision repair	7/1616	42/18670	0.06694	0.4631	0.4295	POLL/APEX2/POLB/XRCC1/RPA2/SMUG1/RPA1	7
BP	GO:0015749	monosaccharide transmembrane transport	15/1616	114/18670	0.067	0.4631	0.4295	SLC5A3/YES1/ADIPOR2/NFE2L2/TRIB3/PIK3R1/PRKAG2/GSK3A/SLC2A1/SLC50A1/HK2/IRS2/TSC1/PRKCI/SLC2A9	15
BP	GO:0042770	signal transduction in response to DNA damage	17/1616	133/18670	0.06709	0.4632	0.4296	PRMT1/CARM1/BATF/CHEK2/CASP9/CDKN1B/TWIST1/BID/BTG2/GADD45A/ATAD5/STK33/EP300/TFDP2/CNOT6L/CDKN1A/SIRT1	17
BP	GO:0001916	positive regulation of T cell mediated cytotoxicity	5/1616	26/18670	0.06891	0.4697	0.4357	FADD/IL12A/HLA-H/HLA-A/HLA-C	5
BP	GO:0021591	ventricular system development	5/1616	26/18670	0.06891	0.4697	0.4357	MYH10/MNAT1/MBOAT7/RAPGEF2/MECP2	5
BP	GO:0042745	circadian sleep/wake cycle	5/1616	26/18670	0.06891	0.4697	0.4357	AHCY/BTBD9/PER3/NR1D1/ADORA2A	5
BP	GO:0048753	pigment granule organization	5/1616	26/18670	0.06891	0.4697	0.4357	BLOC1S5/TRAPPC6A/SNAPIN/BLOC1S4/KIF13A	5
BP	GO:0060740	prostate gland epithelium morphogenesis	5/1616	26/18670	0.06891	0.4697	0.4357	NOTCH1/FEM1B/FRS2/BMP4/TP63	5
BP	GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	5/1616	26/18670	0.06891	0.4697	0.4357	NMT1/BID/YWHAZ/TFDP2/TP63	5
BP	GO:1900740	positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	5/1616	26/18670	0.06891	0.4697	0.4357	NMT1/BID/YWHAZ/TFDP2/TP63	5
BP	GO:0019884	antigen processing and presentation of exogenous antigen	22/1616	182/18670	0.06891	0.4697	0.4357	IKBKB/DCTN4/TRAF6/KIF22/SNAP23/PSME2/AP2S1/DNM2/PSMD5/TAP1/CAPZB/PSMA5/IFI30/PSMA2/HLA-H/PSME4/DYNC1LI2/HLA-A/PSMB3/DYNLL1/HLA-C/PSMD2	22
BP	GO:0032212	positive regulation of telomere maintenance via telomerase	6/1616	34/18670	0.06901	0.4697	0.4357	CCT5/CCT6A/ACD/TNKS/TNKS2/HNRNPA1	6
BP	GO:0042558	pteridine-containing compound metabolic process	6/1616	34/18670	0.06901	0.4697	0.4357	GART/MTHFS/GCH1/DHFR/MTHFD2L/MTHFD1L	6
BP	GO:0043276	anoikis	6/1616	34/18670	0.06901	0.4697	0.4357	NOTCH1/CHEK2/SIK1/MAP3K7/PIK3CA/ANKRD13C	6
BP	GO:0097009	energy homeostasis	6/1616	34/18670	0.06901	0.4697	0.4357	AMPD2/NR1D2/PIK3CA/METRNL/MEX3C/PASK	6
BP	GO:0006888	ER to Golgi vesicle-mediated transport	25/1616	212/18670	0.07001	0.476	0.4415	PDCD6/USO1/TEX261/TBC1D20/YIF1A/LMAN2L/DCTN4/WHAMMP3/INSIG1/SAR1A/WHAMM/GOSR1/TRAPPC6A/RAB30/CSNK1D/GORASP1/CAPZB/MPPE1/RANGRF/COG4/DYNC1LI2/VCP/DYNLL1/TMEM115/RAB1B	25
BP	GO:0072523	purine-containing compound catabolic process	8/1616	51/18670	0.07024	0.4771	0.4424	AHCY/NUDT9/NUDT4/NUDT1/PDE7A/GPX1/PNP/NT5C1A	8
BP	GO:0006165	nucleoside diphosphate phosphorylation	17/1616	134/18670	0.07094	0.4812	0.4463	NUP50/HK1/DTYMK/PGAM4/PRKAG2/NUP133/AAAS/NUP35/PFKFB3/GALK1/PGK2/HK2/PFKL/FOXK2/PFKFB4/PFKP/ENTPD5	17
BP	GO:0042267	natural killer cell mediated cytotoxicity	9/1616	60/18670	0.07188	0.4868	0.4515	PTPN6/CEACAM1/VAV1/IL18RAP/IL12A/LGALS9/MICA/MICB/CORO1A	9
BP	GO:0001910	regulation of leukocyte mediated cytotoxicity	11/1616	78/18670	0.07211	0.4868	0.4515	CEACAM1/VAV1/FADD/IL18RAP/IL12A/LGALS9/MICA/HLA-H/MICB/HLA-A/HLA-C	11
BP	GO:0010827	regulation of glucose transmembrane transport	11/1616	78/18670	0.07211	0.4868	0.4515	YES1/ADIPOR2/NFE2L2/TRIB3/PIK3R1/PRKAG2/GSK3A/SLC2A1/HK2/IRS2/PRKCI	11
BP	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	11/1616	78/18670	0.07211	0.4868	0.4515	CHEK2/PYCARD/JMY/TOPORS/SHISA5/ATAD5/RRN3/EP300/TP63/CDKN1A/SIRT1	11
BP	GO:0007219	Notch signaling pathway	23/1616	193/18670	0.07265	0.4875	0.4521	AAK1/HIF1AN/NOTCH1/NFKBIA/TSPAN14/CREBBP/DTX3L/ASCL1/PDCD10/MYC/CDKN1B/POGLUT1/NOS3/MMP14/CEBPA/CD46/EP300/TSPAN5/MFNG/TP63/BCL6/PRKCI/TGFBR2	23
BP	GO:1901654	response to ketone	23/1616	193/18670	0.07265	0.4875	0.4521	CDK4/AKAP8/NASP/THBS1/CASP9/DUSP1/PSPH/KLF9/PARK7/GBA/CATSPER2/KLF4/BCL2L1/PRKCE/AKR1C2/GNRH1/CAD/NR3C1/ASS1/UBE3A/NCOA2/CDKN1A/SIRT1	23
BP	GO:1902749	regulation of cell cycle G2/M phase transition	25/1616	213/18670	0.07309	0.4875	0.4521	CDK4/FOXN3/ZNF830/CENPJ/PSME2/ODF2/CSNK1E/SFI1/CSNK1D/PSMD5/PSMA5/KIF14/ATAD5/PSMA2/PSME4/BRD4/MECP2/WNT10B/NDE1/CDC25B/PSMB3/DYNLL1/GPR132/HAUS2/PSMD2	25
BP	GO:0030326	embryonic limb morphogenesis	16/1616	125/18670	0.07324	0.4875	0.4521	NOTCH1/ROR2/FZD6/TMEM107/CREBBP/FBXW4/BMP4/TWIST1/HDAC2/IMPAD1/IFT122/FGF9/CRABP2/ALX1/TP63/MKS1	16
BP	GO:0035113	embryonic appendage morphogenesis	16/1616	125/18670	0.07324	0.4875	0.4521	NOTCH1/ROR2/FZD6/TMEM107/CREBBP/FBXW4/BMP4/TWIST1/HDAC2/IMPAD1/IFT122/FGF9/CRABP2/ALX1/TP63/MKS1	16
BP	GO:0006090	pyruvate metabolic process	19/1616	154/18670	0.07353	0.4875	0.4521	NUP50/HK1/PGAM4/PDHA1/PRKAG2/NUP133/AAAS/NUP35/PFKFB3/GALK1/PGK2/HK2/PFKL/FOXK2/PFKFB4/PFKP/DLD/MPC1/ENTPD5	19
BP	GO:0042088	T-helper 1 type immune response	7/1616	43/18670	0.07427	0.4875	0.4521	TRAF6/IL18RAP/IL12A/IL27RA/JAK3/IL18BP/SOCS5	7
BP	GO:0072593	reactive oxygen species metabolic process	32/1616	284/18670	0.07449	0.4875	0.4521	RAC2/ZC3H12A/RFK/NOXA1/DDAH2/NFE2L2/THBS1/PRDX3/PRDX5/GCH1/MPV17/RORA/VAV1/ACP5/PARK7/DHFR/DNM2/NOS3/KLF4/BNIP3/FANCC/GADD45A/HK2/GPX1/CTNS/COQ7/BCO2/ASS1/SIRT5/CDKN1A/FBLN5/TGFBR2	32
BP	GO:0048709	oligodendrocyte differentiation	13/1616	97/18670	0.07484	0.4875	0.4521	NOTCH1/CDK5/ERCC2/IL34/CXCR4/CSK/CNP/WDR1/ASCL1/NLGN3/BNIP3/HDAC2/VTN	13
BP	GO:0046488	phosphatidylinositol metabolic process	21/1616	174/18670	0.07513	0.4875	0.4521	CISH/PIGA/PI4KAP1/PLCH2/SOCS3/PIK3R1/PIK3CA/SOCS2/PLCB1/IP6K1/MTMR14/MBOAT7/AGAP2/PIGH/IMPAD1/MPPE1/PIGL/BPNT1/DPM1/SOCS5/GPAA1	21
BP	GO:2001252	positive regulation of chromosome organization	21/1616	174/18670	0.07513	0.4875	0.4521	CCT5/AKAP8/PHF1/SMARCB1/MIER1/SFPQ/CCT6A/ACD/KAT7/TNKS/JARID2/BRD4/AKAP8L/MECP2/TNKS2/WDR61/HNRNPA1/DDX11/BCL6/TET1/SIRT1	21
BP	GO:0031098	stress-activated protein kinase signaling cascade	35/1616	315/18670	0.0755	0.4875	0.4521	PER1/PRMT1/IKBKB/ROR2/SEMA4C/ZC3H12A/PYCARD/MEN1/TRAF6/STRADB/MUL1/DUSP1/MAP3K7/MAP3K3/MAP3K14/PLCB1/PDCD10/MYC/CD27/KAT7/RASSF2/MAPK11/RELL1/FLT4/ZFP36L1/GADD45A/LGALS9/MAPK8IP3/PPEF2/DNAJA1/SH2D3C/DAXX/CCDC88C/PHLPP1/TRAF4	35
BP	GO:0002220	innate immune response activating cell surface receptor signaling pathway	15/1616	116/18670	0.07552	0.4875	0.4521	IKBKB/TRAF6/CREBBP/MAP3K7/PSME2/BCL10/PSMD5/PSMA5/PSMA2/MUCL1/EP300/PSME4/PSMB3/RAF1/PSMD2	15
BP	GO:0034219	carbohydrate transmembrane transport	15/1616	116/18670	0.07552	0.4875	0.4521	SLC5A3/YES1/ADIPOR2/NFE2L2/TRIB3/PIK3R1/PRKAG2/GSK3A/SLC2A1/SLC50A1/HK2/IRS2/TSC1/PRKCI/SLC2A9	15
BP	GO:0002544	chronic inflammatory response	4/1616	19/18670	0.07599	0.4875	0.4521	CXCL13/AHCY/TNFAIP3/THBS1	4
BP	GO:0045947	negative regulation of translational initiation	4/1616	19/18670	0.07599	0.4875	0.4521	RBM4/ATF4/PAIP2/EIF2AK4	4
BP	GO:0046112	nucleobase biosynthetic process	4/1616	19/18670	0.07599	0.4875	0.4521	GART/DHODH/CAD/MTHFD1L	4
BP	GO:0046597	negative regulation of viral entry into host cell	4/1616	19/18670	0.07599	0.4875	0.4521	IFITM2/TRIM11/IFITM1/IFITM3	4
BP	GO:0060149	negative regulation of posttranscriptional gene silencing	4/1616	19/18670	0.07599	0.4875	0.4521	ZC3H12A/NEAT1/ELAVL1/ZC3H10	4
BP	GO:0060967	negative regulation of gene silencing by RNA	4/1616	19/18670	0.07599	0.4875	0.4521	ZC3H12A/NEAT1/ELAVL1/ZC3H10	4
BP	GO:0090670	RNA localization to Cajal body	4/1616	19/18670	0.07599	0.4875	0.4521	CCT5/NOP10/CCT6A/DCP2	4
BP	GO:0090671	telomerase RNA localization to Cajal body	4/1616	19/18670	0.07599	0.4875	0.4521	CCT5/NOP10/CCT6A/DCP2	4
BP	GO:0090672	telomerase RNA localization	4/1616	19/18670	0.07599	0.4875	0.4521	CCT5/NOP10/CCT6A/DCP2	4
BP	GO:0090685	RNA localization to nucleus	4/1616	19/18670	0.07599	0.4875	0.4521	CCT5/NOP10/CCT6A/DCP2	4
BP	GO:1902074	response to salt	4/1616	19/18670	0.07599	0.4875	0.4521	ZC3H12A/ZNF16/HNRNPA1/DAXX	4
BP	GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	4/1616	19/18670	0.07599	0.4875	0.4521	NFE2L2/PARK7/GPX1/SIRT1	4
BP	GO:0071453	cellular response to oxygen levels	27/1616	234/18670	0.07613	0.4875	0.4521	EGLN2/ENDOG/HIF1AN/NOTCH1/EGLN3/NFE2L2/CREBBP/PSME2/RORA/MYC/TWIST1/BNIP3/PSMD5/ZFP36L1/PSMA5/PRKCE/PSMA2/TMEM199/GATA6/ATP6V1G1/EP300/ATF4/PSME4/TSC1/PSMB3/PSMD2/SIRT1	27
BP	GO:0006473	protein acetylation	24/1616	204/18670	0.07619	0.4875	0.4521	PER1/SMARCB1/TERF2IP/CREBBP/MORF4L1/MAP3K7/ACTL6A/ING5/KAT7/PARK7/MBIP/TWIST1/KANSL2/HDAC2/BRPF1/RSF1/ATAT1/GTF3C4/EP300/PHF20/MECP2/BRD1/TADA1/SIRT1	24
BP	GO:1903725	regulation of phospholipid metabolic process	12/1616	88/18670	0.07637	0.4875	0.4521	CISH/SOCS3/PIK3R1/WDR91/SOCS2/WDR81/P2RY12/AGAP2/KLF4/ATG14/ACSL3/SOCS5	12
BP	GO:0016447	somatic recombination of immunoglobulin gene segments	8/1616	52/18670	0.07702	0.4875	0.4521	BATF/POLB/SWAP70/AICDA/ATAD5/CLCF1/IL27RA/BCL6	8
BP	GO:0051438	regulation of ubiquitin-protein transferase activity	8/1616	52/18670	0.07702	0.4875	0.4521	FEM1B/TOPORS/DTX3L/TRIB3/PARK7/MASTL/GORASP1/ARRDC4	8
BP	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	6/1616	35/18670	0.07747	0.4875	0.4521	WDR46/BYSL/ABT1/TBL3/FAM207A/UTP23	6
BP	GO:0032801	receptor catabolic process	6/1616	35/18670	0.07747	0.4875	0.4521	SNX25/CDK5/DTX3L/SH3GLB1/AP2S1/SMURF1	6
BP	GO:0046466	membrane lipid catabolic process	6/1616	35/18670	0.07747	0.4875	0.4521	NAGA/GBA/GALC/ASAH2B/SMPD4/GM2A	6
BP	GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway	6/1616	35/18670	0.07747	0.4875	0.4521	NFKBIA/TRAF6/TNFAIP3/MAP3K7/HSPA1A/IRGM	6
BP	GO:0071108	protein K48-linked deubiquitination	6/1616	35/18670	0.07747	0.4875	0.4521	TNFAIP3/PARK7/OTUD4/USP5/BAP1/YOD1	6
BP	GO:0098751	bone cell development	6/1616	35/18670	0.07747	0.4875	0.4521	ABI1/PTPN6/SRF/FLI1/SH2B3/EP300	6
BP	GO:0032479	regulation of type I interferon production	16/1616	126/18670	0.07749	0.4875	0.4521	IRF7/PPM1B/ISG15/PYCARD/TNFAIP3/CREBBP/REL/POLR2H/NFKB2/ZCCHC3/RNF26/GPATCH3/RNF125/EP300/PQBP1/DDX58	16
BP	GO:0001570	vasculogenesis	11/1616	79/18670	0.07754	0.4875	0.4521	HIF1AN/NOTCH1/RASIP1/CEACAM1/MYO1E/JUNB/ZFP36L1/GLMN/RAPGEF2/WARS2/TGFBR2	11
BP	GO:1903902	positive regulation of viral life cycle	9/1616	61/18670	0.07816	0.4875	0.4521	TBC1D20/NOTCH1/IFIT1/VPS37B/PKN2/TRIM11/DDB1/TSG101/LGALS9	9
BP	GO:0002709	regulation of T cell mediated immunity	10/1616	70/18670	0.07822	0.4875	0.4521	ZBTB1/TRAF6/RSAD2/MAP3K7/CEACAM1/FADD/IL12A/HLA-H/HLA-A/HLA-C	10
BP	GO:0007004	telomere maintenance via telomerase	10/1616	70/18670	0.07822	0.4875	0.4521	CCT5/NOP10/TERF2IP/CCT6A/ACD/DCP2/TNKS/TNKS2/HNRNPA1/RPA1	10
BP	GO:0061515	myeloid cell development	10/1616	70/18670	0.07822	0.4875	0.4521	ABI1/PTPN6/SRF/ERCC2/L3MBTL3/FLI1/SH2B3/EP300/BCL6/SLC11A2	10
BP	GO:0006644	phospholipid metabolic process	46/1616	430/18670	0.07843	0.4875	0.4521	CISH/SERINC3/PIGA/ETNK1/FDPS/PMVK/PI4KAP1/PLCH2/MVK/SOCS3/CHKB/SAMD8/PIK3R1/PIK3CA/WDR91/SOCS2/PLCB1/IP6K1/FITM1/MTMR14/MBOAT7/WDR81/P2RY12/AGAP2/NAPEPLD/KLF4/SERINC1/PLA2G15/SMPD4/ATG14/PIGH/IMPAD1/LPCAT3/GPAM/MPPE1/GATA6/ACSL3/MECP2/PIGL/BPNT1/DPM1/ABHD6/SOCS5/SPTLC2/APOA1/GPAA1	46
BP	GO:0006735	NADH regeneration	5/1616	27/18670	0.07881	0.4875	0.4521	HK1/HK2/PFKL/FOXK2/PFKP	5
BP	GO:0007176	regulation of epidermal growth factor-activated receptor activity	5/1616	27/18670	0.07881	0.4875	0.4521	SOCS4/TSG101/CBLB/ZGPAT/SOCS5	5
BP	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	5/1616	27/18670	0.07881	0.4875	0.4521	CDK4/BRD4/MECP2/WNT10B/CDC25B	5
BP	GO:0018195	peptidyl-arginine modification	5/1616	27/18670	0.07881	0.4875	0.4521	PRMT1/CARM1/PRDM4/PARK7/PRMT2	5
BP	GO:0035883	enteroendocrine cell differentiation	5/1616	27/18670	0.07881	0.4875	0.4521	MEN1/GSK3A/BMP4/GATA6/RFX3	5
BP	GO:0043921	modulation by host of viral transcription	5/1616	27/18670	0.07881	0.4875	0.4521	CCNT1/TAF11/SMARCB1/EP300/ZNF639	5
BP	GO:0052472	modulation by host of symbiont transcription	5/1616	27/18670	0.07881	0.4875	0.4521	CCNT1/TAF11/SMARCB1/EP300/ZNF639	5
BP	GO:0061621	canonical glycolysis	5/1616	27/18670	0.07881	0.4875	0.4521	HK1/HK2/PFKL/FOXK2/PFKP	5
BP	GO:0061718	glucose catabolic process to pyruvate	5/1616	27/18670	0.07881	0.4875	0.4521	HK1/HK2/PFKL/FOXK2/PFKP	5
BP	GO:0090169	regulation of spindle assembly	5/1616	27/18670	0.07881	0.4875	0.4521	STAG2/HSPA1A/CCSAP/RNF4/GPSM2	5
BP	GO:1902175	regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	5/1616	27/18670	0.07881	0.4875	0.4521	NFE2L2/SFPQ/PARK7/GPX1/SIRT1	5
BP	GO:1904357	negative regulation of telomere maintenance via telomere lengthening	5/1616	27/18670	0.07881	0.4875	0.4521	ACD/DCP2/TNKS/TNKS2/HNRNPA1	5
BP	GO:0001682	tRNA 5'-leader removal	3/1616	12/18670	0.07885	0.4875	0.4521	RPP14/POP1/RPP40	3
BP	GO:0002371	dendritic cell cytokine production	3/1616	12/18670	0.07885	0.4875	0.4521	BST2/JAK3/DDX58	3
BP	GO:0002903	negative regulation of B cell apoptotic process	3/1616	12/18670	0.07885	0.4875	0.4521	BCL10/IRS2/BCL6	3
BP	GO:0006020	inositol metabolic process	3/1616	12/18670	0.07885	0.4875	0.4521	SLC5A3/IMPAD1/MECP2	3
BP	GO:0006527	arginine catabolic process	3/1616	12/18670	0.07885	0.4875	0.4521	DDAH2/NOS3/FAH	3
BP	GO:0006563	L-serine metabolic process	3/1616	12/18670	0.07885	0.4875	0.4521	PSAT1/SERINC3/PSPH	3
BP	GO:0014029	neural crest formation	3/1616	12/18670	0.07885	0.4875	0.4521	PDCD6/KBTBD8/GSC	3
BP	GO:0030259	lipid glycosylation	3/1616	12/18670	0.07885	0.4875	0.4521	ABO/ST3GAL2/GBA	3
BP	GO:0035437	maintenance of protein localization in endoplasmic reticulum	3/1616	12/18670	0.07885	0.4875	0.4521	INSIG1/ANKRD13C/GPAA1	3
BP	GO:0035751	regulation of lysosomal lumen pH	3/1616	12/18670	0.07885	0.4875	0.4521	GRN/SNAPIN/TMEM199	3
BP	GO:0042416	dopamine biosynthetic process	3/1616	12/18670	0.07885	0.4875	0.4521	NR4A2/GCH1/PARK7	3
BP	GO:0046520	sphingoid biosynthetic process	3/1616	12/18670	0.07885	0.4875	0.4521	GBA/ASAH2B/SPTLC2	3
BP	GO:0051095	regulation of helicase activity	3/1616	12/18670	0.07885	0.4875	0.4521	IFIT1/MNAT1/SIRT1	3
BP	GO:0060442	branching involved in prostate gland morphogenesis	3/1616	12/18670	0.07885	0.4875	0.4521	FEM1B/FRS2/BMP4	3
BP	GO:0060742	epithelial cell differentiation involved in prostate gland development	3/1616	12/18670	0.07885	0.4875	0.4521	NOTCH1/FEM1B/TP63	3
BP	GO:0060788	ectodermal placode formation	3/1616	12/18670	0.07885	0.4875	0.4521	FRS2/HDAC2/DKK4	3
BP	GO:0071697	ectodermal placode morphogenesis	3/1616	12/18670	0.07885	0.4875	0.4521	FRS2/HDAC2/DKK4	3
BP	GO:0072697	protein localization to cell cortex	3/1616	12/18670	0.07885	0.4875	0.4521	EPB41L2/GPSM2/SAPCD2	3
BP	GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress	3/1616	12/18670	0.07885	0.4875	0.4521	HIF1AN/HSPA1A/DNAJB1	3
BP	GO:0097284	hepatocyte apoptotic process	3/1616	12/18670	0.07885	0.4875	0.4521	BID/BCL2L1/KRT8	3
BP	GO:0098974	postsynaptic actin cytoskeleton organization	3/1616	12/18670	0.07885	0.4875	0.4521	MYH10/ACTG1/ACTB	3
BP	GO:1900165	negative regulation of interleukin-6 secretion	3/1616	12/18670	0.07885	0.4875	0.4521	ZC3H12A/C1QTNF3/IL27RA	3
BP	GO:2000232	regulation of rRNA processing	3/1616	12/18670	0.07885	0.4875	0.4521	TRMT112/WDR75/UTP15	3
BP	GO:0046939	nucleotide phosphorylation	17/1616	136/18670	0.07906	0.4883	0.4528	NUP50/HK1/DTYMK/PGAM4/PRKAG2/NUP133/AAAS/NUP35/PFKFB3/GALK1/PGK2/HK2/PFKL/FOXK2/PFKFB4/PFKP/ENTPD5	17
BP	GO:0046394	carboxylic acid biosynthetic process	49/1616	462/18670	0.07984	0.4925	0.4568	PSAT1/NUP50/SERINC3/GART/HK1/PGAM4/ALDH8A1/MTHFS/PRKAB1/BCAT1/ADIPOR2/INSIG1/TRIB3/CEACAM1/UGDH/PRKAG2/GSTM4/CBR4/GCH1/CYP2D6/PSPH/NUP133/PARK7/DHFR/AAAS/MTHFD2L/NUP35/PECR/ASAH2B/PTGS1/PFKFB3/ALDH18A1/GALK1/PGK2/ACSL3/HK2/NR1D1/CRABP2/PFKL/CAD/MTHFD1L/ASS1/FOXK2/CTH/PFKFB4/PFKP/MCAT/SIRT1/ENTPD5	49
BP	GO:0022904	respiratory electron transport chain	15/1616	117/18670	0.08003	0.4925	0.4568	NDUFS7/ETFA/NDUFS2/NDUFA12/NDUFB8/PARK7/BID/NDUFB11/NDUFB2/MECP2/ETFB/NDUFB10/COQ9/DLD/D2HGDH	15
BP	GO:0031398	positive regulation of protein ubiquitination	15/1616	117/18670	0.08003	0.4925	0.4568	PDCD6/PHF23/TOPORS/TRAF6/TRIB3/SPRTN/NDFIP2/GSK3A/BCL10/MASTL/GORASP1/SENP2/ARRDC4/SKP2/UBE3A	15
BP	GO:0044262	cellular carbohydrate metabolic process	32/1616	286/18670	0.08009	0.4925	0.4568	NAGK/SLC5A3/HK1/XYLB/PPP1R3D/SIK1/FGGY/PRKAG2/CSGALNACT2/RORA/SORD/GSK3A/C1QTNF3/GALK2/GBE1/DDB1/IMPAD1/SLC2A1/PFKFB3/PRKCE/GALK1/EP300/HK2/NR1D1/MECP2/IRS2/FOXK2/PFKFB4/NCOA2/GK/PASK/SIRT1	32
BP	GO:0002224	toll-like receptor signaling pathway	18/1616	146/18670	0.0803	0.4928	0.457	IRF7/NFKBIA/IKBKB/TLR5/TRAF6/MAPKAPK3/TNFAIP3/RSAD2/UNC93B1/MAP3K7/BCL10/FADD/RAB11FIP2/OTUD4/PRKCE/CTSK/NR1D1/GFI1	18
BP	GO:0042542	response to hydrogen peroxide	18/1616	146/18670	0.0803	0.4928	0.457	ENDOG/TNFAIP3/NFE2L2/DUSP1/PRDX3/PDCD10/PPP1R15B/PARK7/KLF4/BNIP3/HDAC2/IL18RAP/ADAM9/SIGMAR1/GPX1/COL1A1/UBE3A/SIRT1	18
BP	GO:0006195	purine nucleotide catabolic process	7/1616	44/18670	0.08204	0.5012	0.4648	NUDT9/NUDT4/NUDT1/PDE7A/GPX1/PNP/NT5C1A	7
BP	GO:0030225	macrophage differentiation	7/1616	44/18670	0.08204	0.5012	0.4648	ROR2/IL34/L3MBTL3/FADD/BMP4/CEBPA/SIRT1	7
BP	GO:0042269	regulation of natural killer cell mediated cytotoxicity	7/1616	44/18670	0.08204	0.5012	0.4648	CEACAM1/VAV1/IL18RAP/IL12A/LGALS9/MICA/MICB	7
BP	GO:1903214	regulation of protein targeting to mitochondrion	7/1616	44/18670	0.08204	0.5012	0.4648	RAC2/PDCD5/SH3GLB1/HAX1/GSK3A/BAP1/HSPA1L	7
BP	GO:0016053	organic acid biosynthetic process	49/1616	463/18670	0.0821	0.5012	0.4648	PSAT1/NUP50/SERINC3/GART/HK1/PGAM4/ALDH8A1/MTHFS/PRKAB1/BCAT1/ADIPOR2/INSIG1/TRIB3/CEACAM1/UGDH/PRKAG2/GSTM4/CBR4/GCH1/CYP2D6/PSPH/NUP133/PARK7/DHFR/AAAS/MTHFD2L/NUP35/PECR/ASAH2B/PTGS1/PFKFB3/ALDH18A1/GALK1/PGK2/ACSL3/HK2/NR1D1/CRABP2/PFKL/CAD/MTHFD1L/ASS1/FOXK2/CTH/PFKFB4/PFKP/MCAT/SIRT1/ENTPD5	49
BP	GO:0032526	response to retinoic acid	14/1616	108/18670	0.08254	0.5022	0.4658	YES1/DUSP1/ASCL1/CTSH/RXRB/TWF2/KLF4/HDAC2/CDKN2D/ADNP2/MICB/ASXL1/WNT10B/COL1A1	14
BP	GO:0071156	regulation of cell cycle arrest	14/1616	108/18670	0.08254	0.5022	0.4658	CDK4/SDE2/PRMT1/CDK5/CARM1/CHEK2/CDKN1B/BTG2/GADD45A/GATA6/EP300/TFDP2/CNOT6L/CDKN1A	14
BP	GO:1904659	glucose transmembrane transport	14/1616	108/18670	0.08254	0.5022	0.4658	SLC5A3/YES1/ADIPOR2/NFE2L2/TRIB3/PIK3R1/PRKAG2/GSK3A/SLC2A1/HK2/IRS2/TSC1/PRKCI/SLC2A9	14
BP	GO:0030308	negative regulation of cell growth	22/1616	186/18670	0.08279	0.5033	0.4667	OSGIN2/PHB/CDK5/SERTAD2/GNG4/SEMA4C/ADIPOR2/MUL1/SEMA4F/GSK3A/ACVR1B/CDKN1B/HSPA1A/TSPYL2/CDKN2D/BST2/CDKN2AIP/OSGIN1/BCL6/ARHGAP4/CDKN1A/SIRT1	22
BP	GO:0002699	positive regulation of immune effector process	25/1616	216/18670	0.08291	0.5034	0.4669	RAC2/PHB/HK1/ZBTB1/TRAF6/RSAD2/ANKRD17/MAP3K7/VAV1/BCL10/FADD/IL18RAP/ZCCHC3/IL12A/ATAD5/LGALS9/CLCF1/CD46/MICA/HLA-H/MICB/HLA-A/DDX58/HLA-C/SOCS5	25
BP	GO:0043462	regulation of ATPase activity	11/1616	80/18670	0.08323	0.5043	0.4677	AHSA1/ATP2A1/DNM2/TNNT3/ATP1B2/DNAJB1/GTF2H4/DNAJA1/TOR1AIP1/TSC1/DYNLL1	11
BP	GO:0048194	Golgi vesicle budding	11/1616	80/18670	0.08323	0.5043	0.4677	PDCD6/USO1/TBC1D20/GOLPH3L/INSIG1/SAR1A/TRAPPC6A/CSNK1D/GORASP1/PRKCI/RAB1B	11
BP	GO:0000186	activation of MAPKK activity	8/1616	53/18670	0.08418	0.5085	0.4716	MAP3K7/MAP3K3/MAP3K14/FRS2/BMP4/ADAM9/RAF1/LAMTOR2	8
BP	GO:0032715	negative regulation of interleukin-6 production	8/1616	53/18670	0.08418	0.5085	0.4716	PTPN6/ZC3H12A/CSK/TNFAIP3/C1QTNF3/GBA/IL27RA/SOCS5	8
BP	GO:0036297	interstrand cross-link repair	8/1616	53/18670	0.08418	0.5085	0.4716	WDR48/FANCE/RPA2/FANCC/RPA1/MCM9/MUS81/ATRIP	8
BP	GO:0019359	nicotinamide nucleotide biosynthetic process	18/1616	147/18670	0.08446	0.5092	0.4722	NUP50/PARP10/HK1/PGAM4/PRKAG2/NUP133/ASPDH/AAAS/NUP35/PFKFB3/GALK1/PGK2/HK2/PFKL/FOXK2/PFKFB4/PFKP/ENTPD5	18
BP	GO:0019363	pyridine nucleotide biosynthetic process	18/1616	147/18670	0.08446	0.5092	0.4722	NUP50/PARP10/HK1/PGAM4/PRKAG2/NUP133/ASPDH/AAAS/NUP35/PFKFB3/GALK1/PGK2/HK2/PFKL/FOXK2/PFKFB4/PFKP/ENTPD5	18
BP	GO:0007585	respiratory gaseous exchange	9/1616	62/18670	0.08477	0.5105	0.4734	SLC5A3/NR4A2/NDUFA12/FLT4/NLGN3/FTO/MECP2/TRAF4/PASK	9
BP	GO:0072527	pyrimidine-containing compound metabolic process	13/1616	99/18670	0.08494	0.511	0.4739	DTYMK/TKTL1/TBPL1/AICDA/GPAM/DCTPP1/DHODH/SLC25A19/CAD/SMUG1/TET1/NT5C1A/AK3	13
BP	GO:0031570	DNA integrity checkpoint	19/1616	157/18670	0.08531	0.5126	0.4754	PRMT1/FOXN3/FEM1B/CARM1/CHEK2/ZNF830/CDKN1B/BTG2/RPA2/ETAA1/GADD45A/STK33/EP300/TFDP2/CNOT6L/EIF2AK4/MUS81/CDKN1A/ATRIP	19
BP	GO:0032984	protein-containing complex disassembly	36/1616	329/18670	0.08558	0.5138	0.4765	MRPS5/MRPS18C/MRPS26/PHF23/SMARCB1/CAMSAP3/CFL2/MTRF1L/FRAT1/MRPL51/TRMT112/SWAP70/WDR1/MYC/SMCR8/GBA/MRPL54/SCAF8/TWF2/BNIP3/MRPL15/CAPZB/ATG14/CCSAP/SNAPIN/MRPL44/TSG101/CFL1/TWF1/ERAL1/IRGM/VCP/MRPS21/MRPL24/MAP1A/UPF1	36
BP	GO:0033209	tumor necrosis factor-mediated signaling pathway	20/1616	167/18670	0.08591	0.5152	0.4778	SPATA2/TNFRSF6B/NFKBIA/IKBKB/PYCARD/TNFAIP3/MAP3K14/PSME2/CD27/HSPA1A/TXNDC17/PSMD5/RBCK1/PSMA5/PSMA2/PSME4/PSMB3/KRT8/APOA1/PSMD2	20
BP	GO:0036294	cellular response to decreased oxygen levels	25/1616	217/18670	0.08636	0.516	0.4785	EGLN2/ENDOG/HIF1AN/NOTCH1/EGLN3/NFE2L2/CREBBP/PSME2/RORA/MYC/TWIST1/BNIP3/PSMD5/ZFP36L1/PSMA5/PRKCE/PSMA2/GATA6/EP300/ATF4/PSME4/TSC1/PSMB3/PSMD2/SIRT1	25
BP	GO:0032606	type I interferon production	16/1616	128/18670	0.08644	0.516	0.4785	IRF7/PPM1B/ISG15/PYCARD/TNFAIP3/CREBBP/REL/POLR2H/NFKB2/ZCCHC3/RNF26/GPATCH3/RNF125/EP300/PQBP1/DDX58	16
BP	GO:0006007	glucose catabolic process	6/1616	36/18670	0.08649	0.516	0.4785	HK1/TKTL1/HK2/PFKL/FOXK2/PFKP	6
BP	GO:0035872	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	6/1616	36/18670	0.08649	0.516	0.4785	NFKBIA/TRAF6/TNFAIP3/MAP3K7/HSPA1A/IRGM	6
BP	GO:0090322	regulation of superoxide metabolic process	6/1616	36/18670	0.08649	0.516	0.4785	NFE2L2/GCH1/ACP5/PARK7/DHFR/FBLN5	6
BP	GO:0031058	positive regulation of histone modification	12/1616	90/18670	0.08719	0.5179	0.4803	AKAP8/PHF1/SMARCB1/KAT7/JARID2/BRD4/AKAP8L/MECP2/WDR61/BCL6/TET1/SIRT1	12
BP	GO:0009167	purine ribonucleoside monophosphate metabolic process	37/1616	340/18670	0.08745	0.5179	0.4803	NUP50/NDUFS7/GART/HK1/AMPD2/NDUFS2/PGAM4/NDUFA12/PRKAG2/NUDT9/NUP133/NDUFB8/NUDT4/PARK7/AAAS/HSPA1A/BID/NUP35/VPS9D1/PFKFB3/NDUFB11/GALK1/NDUFB2/PGK2/HK2/MECP2/CTNS/PFKL/VCP/NDUFB10/FOXK2/COQ9/PFKFB4/PFKP/DLD/ENTPD5/AK3	37
BP	GO:0006525	arginine metabolic process	4/1616	20/18670	0.08876	0.5179	0.4803	DDAH2/NOS3/FAH/ASS1	4
BP	GO:0007549	dosage compensation	4/1616	20/18670	0.08876	0.5179	0.4803	EIF1/CDYL/UPF1/RLIM	4
BP	GO:0009219	pyrimidine deoxyribonucleotide metabolic process	4/1616	20/18670	0.08876	0.5179	0.4803	DTYMK/TBPL1/DCTPP1/SMUG1	4
BP	GO:0010042	response to manganese ion	4/1616	20/18670	0.08876	0.5179	0.4803	ADAM9/ATF4/D2HGDH/ATP13A2	4
BP	GO:0010592	positive regulation of lamellipodium assembly	4/1616	20/18670	0.08876	0.5179	0.4803	RAC2/DNM2/TWF2/NCKAP1	4
BP	GO:0016137	glycoside metabolic process	4/1616	20/18670	0.08876	0.5179	0.4803	NAGA/CBR4/GBA/AKR1C2	4
BP	GO:0031061	negative regulation of histone methylation	4/1616	20/18670	0.08876	0.5179	0.4803	PHF1/SMARCB1/JARID2/SIRT1	4
BP	GO:0033630	positive regulation of cell adhesion mediated by integrin	4/1616	20/18670	0.08876	0.5179	0.4803	PTPN6/CXCL13/P2RY12/ADAM9	4
BP	GO:0045655	regulation of monocyte differentiation	4/1616	20/18670	0.08876	0.5179	0.4803	IRF7/IL34/MYC/ZFP36L1	4
BP	GO:0046655	folic acid metabolic process	4/1616	20/18670	0.08876	0.5179	0.4803	MTHFS/DHFR/MTHFD2L/MTHFD1L	4
BP	GO:0070262	peptidyl-serine dephosphorylation	4/1616	20/18670	0.08876	0.5179	0.4803	DUSP1/SWAP70/PPP1R15B/PPTC7	4
BP	GO:0070932	histone H3 deacetylation	4/1616	20/18670	0.08876	0.5179	0.4803	PER1/SFPQ/HDAC2/SIRT1	4
BP	GO:0070987	error-free translesion synthesis	4/1616	20/18670	0.08876	0.5179	0.4803	SPRTN/RPA2/VCP/RPA1	4
BP	GO:1900151	regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	4/1616	20/18670	0.08876	0.5179	0.4803	TNRC6B/BTG2/ZFP36L1/ZFP36L2	4
BP	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	4/1616	20/18670	0.08876	0.5179	0.4803	PARK7/HSPA1A/BCL2L1/HERPUD1	4
BP	GO:0032204	regulation of telomere maintenance	11/1616	81/18670	0.08917	0.5179	0.4803	CCT5/TERF2IP/CCT6A/XRCC1/ACD/MYC/DCP2/TNKS/TNKS2/HNRNPA1/UPF1	11
BP	GO:0001773	myeloid dendritic cell activation	5/1616	28/18670	0.08943	0.5179	0.4803	BATF/PYCARD/TRAF6/TSPAN32/TGFBR2	5
BP	GO:0001958	endochondral ossification	5/1616	28/18670	0.08943	0.5179	0.4803	BMP4/MMP14/IMPAD1/MEF2D/COL1A1	5
BP	GO:0035456	response to interferon-beta	5/1616	28/18670	0.08943	0.5179	0.4803	IFITM2/BST2/IFITM1/IFITM3/IRGM	5
BP	GO:0036075	replacement ossification	5/1616	28/18670	0.08943	0.5179	0.4803	BMP4/MMP14/IMPAD1/MEF2D/COL1A1	5
BP	GO:0045577	regulation of B cell differentiation	5/1616	28/18670	0.08943	0.5179	0.4803	PTPN6/CD27/ZFP36L1/MMP14/ZFP36L2	5
BP	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway	5/1616	28/18670	0.08943	0.5179	0.4803	PTPN6/GBP1/CEACAM1/ELF1/UBASH3A	5
BP	GO:0052312	modulation of transcription in other organism involved in symbiotic interaction	5/1616	28/18670	0.08943	0.5179	0.4803	CCNT1/TAF11/SMARCB1/EP300/ZNF639	5
BP	GO:0060512	prostate gland morphogenesis	5/1616	28/18670	0.08943	0.5179	0.4803	NOTCH1/FEM1B/FRS2/BMP4/TP63	5
BP	GO:0090344	negative regulation of cell aging	5/1616	28/18670	0.08943	0.5179	0.4803	ZKSCAN3/MAP3K3/TWIST1/BCL6/SIRT1	5
BP	GO:1902745	positive regulation of lamellipodium organization	5/1616	28/18670	0.08943	0.5179	0.4803	RAC2/DNM2/TWF2/CORO1B/NCKAP1	5
BP	GO:0009132	nucleoside diphosphate metabolic process	19/1616	158/18670	0.08949	0.5179	0.4803	NUP50/HK1/DTYMK/PGAM4/PRKAG2/NUDT9/NUP133/AAAS/NUP35/PFKFB3/GALK1/PGK2/HK2/PFKL/FOXK2/PFKFB4/PFKP/ENTPD5/AK3	19
BP	GO:0043467	regulation of generation of precursor metabolites and energy	19/1616	158/18670	0.08949	0.5179	0.4803	NUP50/CISD1/PRELID1/PPP1R3D/PIK3CA/PRKAG2/GSK3A/NUP133/PARK7/AAAS/NUP35/BNIP3/PFKFB3/PGK2/IRS2/VCP/PFKFB4/PASK/ENTPD5	19
BP	GO:0034614	cellular response to reactive oxygen species	20/1616	168/18670	0.08998	0.5192	0.4816	ENDOG/TNFAIP3/NFE2L2/PRDX3/PRDX5/PDCD10/GCH1/MPV17/PARK7/DHFR/DNM2/NOS3/KLF4/BNIP3/HDAC2/IL18RAP/FANCC/SIGMAR1/SIRT1/FBLN5	20
BP	GO:0009124	nucleoside monophosphate biosynthetic process	24/1616	208/18670	0.09019	0.5192	0.4816	NUP50/GART/HK1/AMPD2/PGAM4/RFK/PRKAG2/NUP133/AAAS/NUP35/VPS9D1/PFKFB3/GALK1/PGK2/HK2/PFKL/DHODH/VCP/CAD/FOXK2/PFKFB4/PFKP/ENTPD5/AK3	24
BP	GO:0002820	negative regulation of adaptive immune response	7/1616	45/18670	0.09027	0.5192	0.4816	PTPN6/ZC3H12A/CEACAM1/IL27RA/RC3H2/JAK3/BCL6	7
BP	GO:0048538	thymus development	7/1616	45/18670	0.09027	0.5192	0.4816	SRF/ZBTB1/FADD/AIRE/JARID2/ASXL1/RAF1	7
BP	GO:0007599	hemostasis	37/1616	341/18670	0.09028	0.5192	0.4816	MAFK/VKORC1/PTPN6/IRF2/SRF/ACTG1/FZD6/NFE2L2/THBS1/PIK3R1/CEACAM1/PIK3CA/VAV1/ACTB/P2RY12/NOS3/HDAC2/VTN/FLI1/CAPZB/SH2B3/GGCX/F11/PRKCE/BLOC1S4/YWHAZ/GATA6/FERMT3/COL1A1/HPS6/IFNA10/ADORA2A/MYL12A/RAF1/TSPAN32/FIBP/AK3	37
BP	GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	13/1616	100/18670	0.0903	0.5192	0.4816	ZBTB1/TRAF6/RSAD2/MAP3K7/FADD/IL12A/ATAD5/CLCF1/IL27RA/HLA-H/HLA-A/HLA-C/SOCS5	13
BP	GO:0046890	regulation of lipid biosynthetic process	23/1616	198/18670	0.09035	0.5192	0.4816	CDK4/FDPS/PMVK/ORMDL2/SIK1/MVK/ADIPOR2/INSIG1/TRIB3/SAMD8/CEACAM1/PRKAG2/CYP51A1/AGAP2/CNEP1R1/DHCR7/GPAM/ACSL3/NR1D1/ABHD6/GFI1/APOA1/SIRT1	23
BP	GO:0071214	cellular response to abiotic stimulus	36/1616	331/18670	0.09132	0.5238	0.4858	SDE2/CRY2/GTF2H5/ZBTB1/TNFRSF10B/HYAL3/CHEK2/TLR5/NMT1/CREBBP/CASP9/PIK3R1/ASCL1/TLK2/MAP3K14/PDE6G/MYC/BCL10/MBIP/DNM2/FADD/BNIP3/BCL2L1/ZFP36L1/OPN3/DDB1/SLC2A1/GADD45A/EP300/ATF4/COL1A1/MFAP4/EIF2AK4/CNN2/CDKN1A/SIRT1	36
BP	GO:0104004	cellular response to environmental stimulus	36/1616	331/18670	0.09132	0.5238	0.4858	SDE2/CRY2/GTF2H5/ZBTB1/TNFRSF10B/HYAL3/CHEK2/TLR5/NMT1/CREBBP/CASP9/PIK3R1/ASCL1/TLK2/MAP3K14/PDE6G/MYC/BCL10/MBIP/DNM2/FADD/BNIP3/BCL2L1/ZFP36L1/OPN3/DDB1/SLC2A1/GADD45A/EP300/ATF4/COL1A1/MFAP4/EIF2AK4/CNN2/CDKN1A/SIRT1	36
BP	GO:0046637	regulation of alpha-beta T cell differentiation	9/1616	63/18670	0.0917	0.5245	0.4864	CD83/ZC3H12A/LGALS9/RC3H2/JAK3/BCL6/PNP/SOCS5/TGFBR2	9
BP	GO:1904377	positive regulation of protein localization to cell periphery	9/1616	63/18670	0.0917	0.5245	0.4864	PIK3R1/RAB11FIP2/ITGA3/PRKCE/RANGRF/ACSL3/EPB41L2/PRKCI/GPSM2	9
BP	GO:0090329	regulation of DNA-dependent DNA replication	8/1616	54/18670	0.09172	0.5245	0.4864	CHTF8/STAG2/CHEK2/ZNF830/DBF4/AICDA/SENP2/BCL6	8
BP	GO:0032508	DNA duplex unwinding	14/1616	110/18670	0.09273	0.5298	0.4913	CHTF8/GTF2H5/ERCC2/SUPV3L1/CHD2/MNAT1/DDB1/GTF2H4/RAD54B/CHD9/DDX11/RPA1/MCM9/CHD6	14
BP	GO:0045638	negative regulation of myeloid cell differentiation	12/1616	91/18670	0.09294	0.5299	0.4915	PRMT1/NFKBIA/PIK3R1/CEACAM1/FSTL3/MYC/ZFP36L1/MEIS2/LILRB3/GPR171/WDR61/TOB2	12
BP	GO:0060333	interferon-gamma-mediated signaling pathway	12/1616	91/18670	0.09294	0.5299	0.4915	IRF7/GBP1/IRF2/CAMK2D/SOCS3/OAS2/IFI30/HLA-H/IRGM/HLA-A/HLA-C/OAS1	12
BP	GO:0045619	regulation of lymphocyte differentiation	20/1616	169/18670	0.09417	0.5336	0.4948	CD83/PTPN6/ZBTB1/PRELID1/ZC3H12A/CD27/BMP4/ZFP36L1/MMP14/IL12A/SOS1/LGALS9/CD46/ZFP36L2/RC3H2/JAK3/BCL6/PNP/SOCS5/TGFBR2	20
BP	GO:0050728	negative regulation of inflammatory response	20/1616	169/18670	0.09417	0.5336	0.4948	ZC3H12A/PYCARD/MVK/SOCS3/TNFAIP3/NR1D2/GRN/RORA/ACP5/C1QTNF3/GBA/ASH1L/KLF4/METRNL/TNFAIP8L2/NR1D1/GPX1/ADORA2A/SOCS5/APOA1	20
BP	GO:0051099	positive regulation of binding	21/1616	179/18670	0.09434	0.5336	0.4948	CDK5/ERCC2/MEN1/TRAF6/SPPL3/HIP1R/DTX3L/TRIB3/ACD/TCF7L2/PARK7/BMP4/TWIST1/KLF4/VTN/RAPGEF2/EP300/MFNG/DDX11/CTHRC1/TRAF4	21
BP	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	15/1616	120/18670	0.09461	0.5336	0.4948	SNX25/MEN1/CREBBP/THBS1/CDKN2B/DNM2/HSPA1A/SMURF1/LRG1/ITGA3/EP300/PPM1A/PMEPA1/SIRT1/TGFBR2	15
BP	GO:0072659	protein localization to plasma membrane	29/1616	260/18670	0.09466	0.5336	0.4948	GBP1/GOLPH3L/CDK5/IKBKB/CSK/TSPAN14/PIK3R1/SYS1/MPP5/NSG1/ACTB/SMURF1/GORASP1/BCL2L1/MMP14/ANKRD9/RAB11FIP2/RAB13/ITGA3/PRKCE/RANGRF/RAPGEF2/SYTL2/ACSL3/TSPAN5/GRASP/PRKCI/RAB10/KIF13A	29
BP	GO:0071158	positive regulation of cell cycle arrest	11/1616	82/18670	0.09536	0.5336	0.4948	PRMT1/CARM1/CHEK2/CDKN1B/BTG2/GADD45A/GATA6/EP300/TFDP2/CNOT6L/CDKN1A	11
BP	GO:0016073	snRNA metabolic process	13/1616	101/18670	0.09586	0.5336	0.4948	CCNT1/NOP10/TAF11/POLR2D/RPRD1B/POLR2H/METTL16/EXOSC5/SRRT/TOE1/INTS12/TAF13/ELL2	13
BP	GO:0034405	response to fluid shear stress	6/1616	37/18670	0.09606	0.5336	0.4948	NFE2L2/NOS3/KLF4/ADAM9/ASS1/SOCS5	6
BP	GO:1904358	positive regulation of telomere maintenance via telomere lengthening	6/1616	37/18670	0.09606	0.5336	0.4948	CCT5/CCT6A/ACD/TNKS/TNKS2/HNRNPA1	6
BP	GO:2000142	regulation of DNA-templated transcription, initiation	6/1616	37/18670	0.09606	0.5336	0.4948	SRF/TWIST1/THRA/RRN3/WNT10B/BCLAF1	6
BP	GO:0002829	negative regulation of type 2 immune response	3/1616	13/18670	0.09616	0.5336	0.4948	IL27RA/BCL6/SOCS5	3
BP	GO:0006670	sphingosine metabolic process	3/1616	13/18670	0.09616	0.5336	0.4948	GBA/ASAH2B/SPTLC2	3
BP	GO:0009650	UV protection	3/1616	13/18670	0.09616	0.5336	0.4948	ERCC2/GPX1/MFAP4	3
BP	GO:0016558	protein import into peroxisome matrix	3/1616	13/18670	0.09616	0.5336	0.4948	PEX12/PEX6/PEX16	3
BP	GO:0033127	regulation of histone phosphorylation	3/1616	13/18670	0.09616	0.5336	0.4948	AKAP8/TWIST1/AKAP8L	3
BP	GO:0035641	locomotory exploration behavior	3/1616	13/18670	0.09616	0.5336	0.4948	SLC4A10/PRKCE/C12orf10	3
BP	GO:0043247	telomere maintenance in response to DNA damage	3/1616	13/18670	0.09616	0.5336	0.4948	TERF2IP/XRCC1/ACD	3
BP	GO:0046349	amino sugar biosynthetic process	3/1616	13/18670	0.09616	0.5336	0.4948	NAGK/GNPDA1/GFPT2	3
BP	GO:0048505	regulation of timing of cell differentiation	3/1616	13/18670	0.09616	0.5336	0.4948	NOTCH1/ASCL1/FGF9	3
BP	GO:0050713	negative regulation of interleukin-1 beta secretion	3/1616	13/18670	0.09616	0.5336	0.4948	ZC3H12A/TNFAIP3/APOA1	3
BP	GO:0060712	spongiotrophoblast layer development	3/1616	13/18670	0.09616	0.5336	0.4948	SOCS3/ZFP36L1/SENP2	3
BP	GO:0061000	negative regulation of dendritic spine development	3/1616	13/18670	0.09616	0.5336	0.4948	NLGN3/HDAC2/UBE3A	3
BP	GO:0061042	vascular wound healing	3/1616	13/18670	0.09616	0.5336	0.4948	CXCR4/ADIPOR2/TNFAIP3	3
BP	GO:0061430	bone trabecula morphogenesis	3/1616	13/18670	0.09616	0.5336	0.4948	THBS3/WNT10B/COL1A1	3
BP	GO:0071696	ectodermal placode development	3/1616	13/18670	0.09616	0.5336	0.4948	FRS2/HDAC2/DKK4	3
BP	GO:0090239	regulation of histone H4 acetylation	3/1616	13/18670	0.09616	0.5336	0.4948	SMARCB1/KAT7/SIRT1	3
BP	GO:0090713	immunological memory process	3/1616	13/18670	0.09616	0.5336	0.4948	CD46/TSC1/BCL6	3
BP	GO:1902855	regulation of non-motile cilium assembly	3/1616	13/18670	0.09616	0.5336	0.4948	CENPJ/DNM2/DYNLL1	3
BP	GO:0006066	alcohol metabolic process	39/1616	364/18670	0.09663	0.5357	0.4968	DHRS3/SLC5A3/FDPS/PMVK/PLCH2/MVK/APOL1/INSIG1/SULT2B1/PLCB1/CBR4/GCH1/CYP2D6/SORD/IP6K1/CYP51A1/NUDT4/PARK7/DHFR/GBA/PECR/NAPEPLD/ASAH2B/IMPAD1/CEBPA/DHCR7/RDH14/GPAM/GALK1/DHRS4/AKR1C2/MECP2/DPM1/SULT1B1/LIPE/GFI1/SPTLC2/GK/APOA1	39
BP	GO:0072401	signal transduction involved in DNA integrity checkpoint	10/1616	73/18670	0.09743	0.5388	0.4997	PRMT1/CARM1/CHEK2/CDKN1B/BTG2/GADD45A/EP300/TFDP2/CNOT6L/CDKN1A	10
BP	GO:0072422	signal transduction involved in DNA damage checkpoint	10/1616	73/18670	0.09743	0.5388	0.4997	PRMT1/CARM1/CHEK2/CDKN1B/BTG2/GADD45A/EP300/TFDP2/CNOT6L/CDKN1A	10
BP	GO:0034599	cellular response to oxidative stress	33/1616	302/18670	0.09756	0.5388	0.4997	ENDOG/VKORC1L1/NR4A2/ZC3H12A/BRF2/TNFAIP3/NFE2L2/SFPQ/PRDX3/PRDX5/PDCD10/GCH1/MPV17/PARK7/DHFR/DNM2/HSPA1A/NOS3/KLF4/BNIP3/HDAC2/IL18RAP/FANCC/ADNP2/MGAT3/ATF4/SIGMAR1/GPX1/TSC1/CHD6/ATP13A2/SIRT1/FBLN5	33
BP	GO:0009612	response to mechanical stimulus	24/1616	210/18670	0.09778	0.5388	0.4997	ENDOG/NFKBIA/TNFRSF10B/JUND/CXCR4/TLR5/THBS1/MAP3K14/PSPH/BCL10/FADD/JUNB/BTG2/BNIP3/MMP14/PPL/SLC2A1/GADD45A/MEIS2/COL1A1/RAF1/CNN2/HTT/TGFBR2	24
BP	GO:0016331	morphogenesis of embryonic epithelium	18/1616	150/18670	0.0978	0.5388	0.4997	SEMA4C/FZD6/TRAF6/BCL10/BMP4/TWIST1/VASP/GLMN/CFL1/IFT122/TSC1/MTHFD1L/ALX1/TP63/CTHRC1/NPHP3/MKS1/IFT57	18
BP	GO:0050777	negative regulation of immune response	18/1616	150/18670	0.0978	0.5388	0.4997	PTPN6/ZC3H12A/TNFAIP3/MUL1/CEACAM1/GRN/BST2/LGALS9/TRAFD1/MICA/IL27RA/RC3H2/YTHDF3/GPX1/JAK3/BCL6/SOCS5/APOA1	18
BP	GO:0062012	regulation of small molecule metabolic process	48/1616	459/18670	0.09807	0.5388	0.4997	NUP50/FDPS/PMVK/PPP1R3D/SIK1/MVK/ADIPOR2/INSIG1/TRIB3/CEACAM1/PRKAG2/PSME2/RORA/GSK3A/NUP133/CYP51A1/PARK7/C1QTNF3/AAAS/TWIST1/NUP35/NOS3/PSMD5/DDB1/PSMA5/PFKFB3/DHCR7/GPAM/PRKCE/PSMA2/PGK2/EP300/NR1D1/PSME4/RCVRN/IRS2/VCP/FOXK2/PSMB3/PPTC7/PFKFB4/GFI1/NCOA2/SIRT5/PSMD2/PASK/SIRT1/ENTPD5	48
BP	GO:0060759	regulation of response to cytokine stimulus	22/1616	190/18670	0.09841	0.5388	0.4997	IRF7/SPATA2/PTPN6/IKBKB/PYCARD/CXCR4/SOCS3/TNFAIP3/MUL1/CREBRF/FADD/HSPA1A/KLF4/ELF1/RBCK1/SH2B3/OTUD4/IRGM/YTHDF3/DDX58/GFI1/APOA1	22
BP	GO:0007051	spindle organization	20/1616	170/18670	0.09849	0.5388	0.4997	STAG2/SAC3D1/RGS14/CHEK2/GOLGA6B/AAAS/HSPA1A/CSNK1D/NTMT1/CCSAP/TNKS/GOLGA6C/RNF4/MECP2/VCP/RCC1/TUBGCP5/GPSM2/SBDS/HAUS2	20
BP	GO:0030705	cytoskeleton-dependent intracellular transport	21/1616	180/18670	0.09853	0.5388	0.4997	CAMSAP3/SFPQ/DYNLRB1/BLOC1S5/TTC30A/SNAPIN/BLOC1S4/MAPK8IP3/IFT122/CCDC88A/RAB27B/NDE1/WDR60/WASL/MAP1A/DYNLL1/RHOT2/CCDC88C/HTT/KIF13A/IFT57	21
BP	GO:0006310	DNA recombination	32/1616	292/18670	0.09862	0.5388	0.4997	ENDOG/POLL/ERCC2/WDR48/TERF2IP/BATF/APEX2/POLB/SFPQ/MORF4L1/SUPV3L1/SWAP70/INO80D/XRCC1/PAGR1/ACTL6A/RBM14/RPA2/RMI2/TFPT/AICDA/ATAD5/CLCF1/IL27RA/RAD54B/RNF138/CCNB1IP1/BCL6/RPA1/TSN/MCM9/MUS81	32
BP	GO:0035710	CD4-positive, alpha-beta T cell activation	12/1616	92/18670	0.09891	0.5388	0.4997	CD83/BATF/ZC3H12A/RSAD2/RORA/IL12A/LGALS9/RC3H2/JAK3/BCL6/SOCS5/TGFBR2	12
BP	GO:0002715	regulation of natural killer cell mediated immunity	7/1616	46/18670	0.09894	0.5388	0.4997	CEACAM1/VAV1/IL18RAP/IL12A/LGALS9/MICA/MICB	7
BP	GO:0032527	protein exit from endoplasmic reticulum	7/1616	46/18670	0.09894	0.5388	0.4997	HM13/INSIG1/SAR1A/RANGRF/HERPUD1/VCP/YOD1	7
BP	GO:0043330	response to exogenous dsRNA	7/1616	46/18670	0.09894	0.5388	0.4997	NFKBIA/IFIT1/MUL1/ZCCHC3/PQBP1/IFNA10/DDX58	7
BP	GO:0048512	circadian behavior	7/1616	46/18670	0.09894	0.5388	0.4997	AHCY/NR1D2/BTBD9/PER3/NR1D1/ADORA2A/NCOA2	7
BP	GO:0002228	natural killer cell mediated immunity	9/1616	64/18670	0.09896	0.5388	0.4997	PTPN6/CEACAM1/VAV1/IL18RAP/IL12A/LGALS9/MICA/MICB/CORO1A	9
BP	GO:0016445	somatic diversification of immunoglobulins	9/1616	64/18670	0.09896	0.5388	0.4997	POLL/BATF/POLB/SWAP70/AICDA/ATAD5/CLCF1/IL27RA/BCL6	9
BP	GO:0050922	negative regulation of chemotaxis	9/1616	64/18670	0.09896	0.5388	0.4997	NOTCH1/CXCL13/SEMA4C/THBS1/DUSP1/SEMA4F/CORO1B/DDT/C5	9
CC	GO:0061695	transferase complex, transferring phosphorus-containing groups	41/1674	259/19717	7.549e-05	0.02603	0.02491	CISH/CDK4/POLR2J3/CD3EAP/CCNT1/POLD2/CDK5/NRBF2/IKBKB/CCNJ/GTF2H5/ERCC2/TAF11/POLR2D/PYCARD/SIK1/RPRD1B/POLD4/PRKAB1/CCND3/SOCS3/PRIM1/PIK3R1/MAP3K7/PIK3CA/PRKAG2/SOCS2/POLR2H/MNAT1/ACVR1B/SMCR8/TBPL1/CDKN2D/ATG14/GTF2H4/PFKL/WDR61/TAF13/PFKP/SOCS5/CDKN1A	41
CC	GO:0005759	mitochondrial matrix	64/1674	469/19717	0.0001036	0.02603	0.02491	MRPS5/HMGCL/NDUFS7/MRPS18C/ATAD3A/LYRM7/MRPS26/DTYMK/ETFA/NDUFS2/GRPEL1/BDH1/MTHFS/MTRF1L/MRPL51/PDHA1/SUPV3L1/PRDX3/TFB1M/PRDX5/NSUN4/CBR4/TSFM/NUDT9/RPUSD3/NDUFB8/PARK7/SCO2/TBRG4/FASTKD5/MTHFD2L/TRMT10C/PIN4/MRPL54/PUS1/MRPL15/DARS2/NUDT1/BCL2L1/ALDH4A1/ETHE1/CA5B/MRPL44/TRMT5/TFB2M/IBA57/ERAL1/BCKDK/WARS2/GPX1/ETFB/MRPS21/HSPA1L/MRPL24/MTHFD1L/BCO2/NR3C1/PPTC7/DLD/REXO2/MCAT/SIRT5/D2HGDH/AK3	64
CC	GO:0016607	nuclear speck	56/1674	397/19717	0.0001143	0.02603	0.02491	EHMT2/DUSP11/CRY2/NR4A2/RBM25/WTAP/SNRPA1/POLR2D/CBY1/TOPORS/ZNF830/KIF22/SFPQ/CIR1/MORF4L1/SPRTN/SF3A1/PLCB1/RBM14/AKAP17A/THAP7/GCAT/HSPA1A/RBM19/RBM4B/OSGEP/EAF1/RBM4/RMI2/GADD45A/TATDN2/SF3A2/SRSF11/GTF2H4/FTO/TOE1/CCNL1/SLU7/PSME4/MBD1/PQBP1/AKAP8L/BRD1/SETD1B/SRRM1/UNC45A/PHF5A/SRSF10/CDYL/BAZ2A/ATPAF2/SPOP/NR3C1/RAF1/BCLAF1/FIBP	56
CC	GO:0000123	histone acetyltransferase complex	17/1674	85/19717	0.0006963	0.1189	0.1138	UBAP2L/CREBBP/MORF4L1/MAP3K7/ACTL6A/ENY2/ING5/KAT7/ACTB/MBIP/KANSL2/BRPF1/RSF1/EP300/PHF20/BRD1/TADA1	17
CC	GO:0005942	phosphatidylinositol 3-kinase complex	8/1674	27/19717	0.001358	0.1521	0.1456	CISH/NRBF2/SOCS3/PIK3R1/PIK3CA/SOCS2/ATG14/SOCS5	8
CC	GO:0032580	Golgi cisterna membrane	17/1674	92/19717	0.001746	0.1521	0.1456	ABO/ST6GAL1/GOLPH3L/TMEM87A/GOLGA6B/ST3GAL3/CSGALNACT2/ST3GAL2/NSG1/FUT4/B4GALT4/GOLGA6C/ARAP1/GALNT2/B4GALNT3/TMEM115/GOLGA3	17
CC	GO:1902911	protein kinase complex	19/1674	109/19717	0.001971	0.1521	0.1456	CDK4/CCNT1/CDK5/IKBKB/CCNJ/GTF2H5/ERCC2/PYCARD/SIK1/PRKAB1/CCND3/MAP3K7/PRKAG2/MNAT1/ACVR1B/SMCR8/CDKN2D/GTF2H4/CDKN1A	19
CC	GO:0032585	multivesicular body membrane	5/1674	12/19717	0.002089	0.1521	0.1456	GIMAP5/NDFIP2/NSG1/RAB27B/ATP13A2	5
CC	GO:0031248	protein acetyltransferase complex	17/1674	95/19717	0.002494	0.1521	0.1456	UBAP2L/CREBBP/MORF4L1/MAP3K7/ACTL6A/ENY2/ING5/KAT7/ACTB/MBIP/KANSL2/BRPF1/RSF1/EP300/PHF20/BRD1/TADA1	17
CC	GO:1902493	acetyltransferase complex	17/1674	95/19717	0.002494	0.1521	0.1456	UBAP2L/CREBBP/MORF4L1/MAP3K7/ACTL6A/ENY2/ING5/KAT7/ACTB/MBIP/KANSL2/BRPF1/RSF1/EP300/PHF20/BRD1/TADA1	17
CC	GO:0008180	COP9 signalosome	9/1674	36/19717	0.002565	0.1521	0.1456	NCKIPSD/COPS7A/LAT/DOCK7/HSPA1A/WDR6/EPB41L2/HSPA1L/DYNLL1	9
CC	GO:1902554	serine/threonine protein kinase complex	16/1674	88/19717	0.002789	0.1521	0.1456	CDK4/CCNT1/CDK5/IKBKB/CCNJ/GTF2H5/ERCC2/PYCARD/CCND3/MAP3K7/MNAT1/ACVR1B/SMCR8/CDKN2D/GTF2H4/CDKN1A	16
CC	GO:0005743	mitochondrial inner membrane	58/1674	473/19717	0.002895	0.1521	0.1456	ENDOG/MRPS5/NDUFS7/MRPS18C/ATAD3A/PHB/MRPS26/NDUFS2/GRPEL1/MTFP1/SLC25A30/BDH1/MTCH2/NDUFA12/COA3/MRPL51/MRS2/SCO1/CNP/RSAD2/SLC25A6/BCS1L/C15orf48/MPV17/COQ10B/NDUFB8/SLC25A20/SCO2/GCAT/SLC25A28/SLC25A36/SLC25A4/MTHFD2L/MRPL54/TIMM13/MRPL15/SLC25A38/BCL2L1/NDUFAF3/MRPL44/ALDH18A1/NDUFB11/NDUFB2/ERAL1/TIMMDC1/UCP2/YME1L1/DHODH/SLC25A19/TIMM10/COQ7/NDUFB10/MRPS21/MRPL24/COQ9/CHCHD3/MPC1/SIRT5	58
CC	GO:0031300	intrinsic component of organelle membrane	33/1674	237/19717	0.003292	0.1533	0.1468	TEX261/TBC1D20/PEX12/SLC35A2/YIF1A/SYN1/COA3/SCO1/MUL1/TOMM20L/SLC35A4/SAMD8/CSGALNACT2/SYS1/PEX16/SCO2/PEX11B/ZDHHC9/SLC25A4/BID/EMC6/VAMP1/BNIP3/MFNG/GALNT2/SYNPR/SLC38A9/RAB27B/SLC25A19/RHOT2/CHCHD3/MPC1/ATP13A2	33
CC	GO:0044798	nuclear transcription factor complex	29/1674	201/19717	0.003368	0.1533	0.1468	CD3EAP/MXI1/MED26/GTF2H5/CARM1/ERCC2/TAF11/JUND/BRF2/NR1D2/SFPQ/ASCL1/BRF1/TCF7L2/MNAT1/RXRB/JUNB/KLF4/TBPL1/CEBPA/GTF2H4/THRA/GTF3C4/MED6/NR1D1/ATF4/POU2AF1/TFDP2/TAF13	29
CC	GO:0031985	Golgi cisterna	19/1674	116/19717	0.00406	0.1733	0.1659	ABO/ST6GAL1/GOLPH3L/TMEM87A/GOLGA6B/ST3GAL3/CSGALNACT2/ST3GAL2/NSG1/GOSR1/FUT4/RAB30/B4GALT4/GOLGA6C/ARAP1/GALNT2/B4GALNT3/TMEM115/GOLGA3	19
CC	GO:0031301	integral component of organelle membrane	30/1674	214/19717	0.004448	0.1787	0.171	TEX261/TBC1D20/PEX12/SLC35A2/YIF1A/COA3/SCO1/MUL1/TOMM20L/SLC35A4/SAMD8/CSGALNACT2/SYS1/PEX16/SCO2/PEX11B/SLC25A4/BID/EMC6/VAMP1/BNIP3/MFNG/GALNT2/SYNPR/SLC38A9/SLC25A19/RHOT2/CHCHD3/MPC1/ATP13A2	30
CC	GO:0005868	cytoplasmic dynein complex	6/1674	20/19717	0.005078	0.1927	0.1844	TOPORS/DYNLRB1/DYNLT1/DYNC1LI2/WDR60/DYNLL1	6
CC	GO:0090575	RNA polymerase II transcription factor complex	24/1674	163/19717	0.005582	0.1928	0.1845	MXI1/MED26/GTF2H5/CARM1/ERCC2/TAF11/JUND/NR1D2/SFPQ/ASCL1/TCF7L2/MNAT1/RXRB/JUNB/TBPL1/CEBPA/GTF2H4/THRA/MED6/NR1D1/ATF4/POU2AF1/TFDP2/TAF13	24
CC	GO:0005884	actin filament	18/1674	111/19717	0.005646	0.1928	0.1845	RAC2/ACTG1/YES1/WDR1/VPS18/PDLIM2/TIGD5/TWF2/PALLD/CORO1B/PSTPIP2/TWF1/CORO1A/TSC1/WASL/BIN3/FMN1/NCKAP1	18
CC	GO:0034399	nuclear periphery	20/1674	131/19717	0.007266	0.2326	0.2226	STAG2/AKAP8/ATF7/ATXN7/CFL2/MEN1/ZNF350/SFPQ/ENC1/NUP35/SCAF8/CFL1/ATF4/MBD1/AKAP8L/SRRM1/PHF5A/CAD/GFI1/KRT8	20
CC	GO:0005795	Golgi stack	22/1674	149/19717	0.007491	0.2326	0.2226	USO1/ABO/ST6GAL1/GOLPH3L/TMEM87A/GOLGA6B/RASIP1/ST3GAL3/CSGALNACT2/ST3GAL2/NSG1/GOSR1/FUT4/RAB30/B4GALT4/GOLGA6C/ARAP1/GALNT2/RAB27B/B4GALNT3/TMEM115/GOLGA3	22
CC	GO:0030479	actin cortical patch	5/1674	16/19717	0.008649	0.2363	0.2262	HIP1R/TIGD5/GMFB/WASL/BIN3	5
CC	GO:0061645	endocytic patch	5/1674	16/19717	0.008649	0.2363	0.2262	HIP1R/TIGD5/GMFB/WASL/BIN3	5
CC	GO:0005741	mitochondrial outer membrane	25/1674	178/19717	0.008649	0.2363	0.2262	CPT1B/CISD1/HK1/MOAP1/CPT1C/MTX3/CNP/RSAD2/MUL1/TOMM20L/CYB5B/SH3GLB1/HAX1/BID/VAMP1/BNIP3/BCL2L1/GPAM/ACSL3/HK2/ASS1/RAF1/RHOT2/GK/SLC11A2	25
CC	GO:0016363	nuclear matrix	17/1674	109/19717	0.01032	0.2658	0.2544	STAG2/AKAP8/ATXN7/CFL2/MEN1/ZNF350/SFPQ/ENC1/SCAF8/CFL1/MBD1/AKAP8L/SRRM1/PHF5A/CAD/GFI1/KRT8	17
CC	GO:0002178	palmitoyltransferase complex	4/1674	11/19717	0.01051	0.2658	0.2544	ORMDL2/ZDHHC9/GOLGA7B/SPTLC2	4
CC	GO:0031968	organelle outer membrane	27/1674	201/19717	0.01163	0.2837	0.2716	CPT1B/CISD1/HK1/MOAP1/CPT1C/MTX3/CNP/RSAD2/MUL1/TOMM20L/CYB5B/SH3GLB1/HAX1/BID/VAMP1/BNIP3/BCL2L1/DHCR7/GPAM/ACSL3/HK2/SIGMAR1/ASS1/RAF1/RHOT2/GK/SLC11A2	27
CC	GO:0030027	lamellipodium	26/1674	193/19717	0.01265	0.298	0.2852	ABI1/SLC39A14/RAC2/CDK5/MYH10/SWAP70/CDC42BPA/PIK3CA/HAX1/DNM2/PKN2/TWF2/PALLD/VASP/DYNLT1/CORO1B/RAB13/CFL1/CTNND1/CORO1A/CCDC88A/TSC1/WASL/NCKAP1/ARPC5/FGD1	26
CC	GO:0019867	outer membrane	27/1674	203/19717	0.01315	0.2995	0.2866	CPT1B/CISD1/HK1/MOAP1/CPT1C/MTX3/CNP/RSAD2/MUL1/TOMM20L/CYB5B/SH3GLB1/HAX1/BID/VAMP1/BNIP3/BCL2L1/DHCR7/GPAM/ACSL3/HK2/SIGMAR1/ASS1/RAF1/RHOT2/GK/SLC11A2	27
CC	GO:0005681	spliceosomal complex	25/1674	185/19717	0.01377	0.3033	0.2903	HNRNPA1L2/AAR2/SNRPA1/SNIP1/DHX16/ZNF830/PTBP2/SF3A1/PRKRIP1/AKAP17A/SCAF8/SNRNP25/SF3A2/RBM3/PPIL1/SLU7/CWF19L1/SRRM1/PHF5A/XAB2/HNRNPA1/UPF1/RBM17/HNRNPH3/GPATCH1	25
CC	GO:0090576	RNA polymerase III transcription factor complex	4/1674	12/19717	0.01471	0.3141	0.3006	BRF2/BRF1/TBPL1/GTF3C4	4
CC	GO:0044452	nucleolar part	24/1674	178/19717	0.01596	0.3214	0.3076	USO1/SPATA2/CD3EAP/NFKBIE/NOP10/DUSP11/SMARCB1/ORC6/APEX2/RSAD2/POP1/MAP3K14/POLR2H/IP6K1/TIMM13/TBL3/CDKN2AIP/NFIC/NHEJ1/UTP15/NUAK1/RPP40/DDX11/WDR33	24
CC	GO:0031519	PcG protein complex	9/1674	47/19717	0.016	0.3214	0.3076	PHF1/CBX2/UBAP2L/HDAC2/JARID2/ASXL2/ASXL1/BAP1/SIRT1	9
CC	GO:0032592	integral component of mitochondrial membrane	12/1674	73/19717	0.01939	0.3715	0.3555	COA3/SCO1/MUL1/TOMM20L/SCO2/SLC25A4/BID/BNIP3/SLC25A19/RHOT2/CHCHD3/MPC1	12
CC	GO:0005675	transcription factor TFIIH holo complex	4/1674	13/19717	0.01985	0.3715	0.3555	GTF2H5/ERCC2/MNAT1/GTF2H4	4
CC	GO:0031228	intrinsic component of Golgi membrane	11/1674	65/19717	0.02012	0.3715	0.3555	TEX261/TBC1D20/SLC35A2/YIF1A/SLC35A4/SAMD8/CSGALNACT2/SYS1/ZDHHC9/MFNG/GALNT2	11
CC	GO:0098573	intrinsic component of mitochondrial membrane	12/1674	74/19717	0.02141	0.3848	0.3683	COA3/SCO1/MUL1/TOMM20L/SCO2/SLC25A4/BID/BNIP3/SLC25A19/RHOT2/CHCHD3/MPC1	12
CC	GO:0000932	P-body	13/1674	84/19717	0.0244	0.4222	0.404	EDC3/DCP1A/POLR2D/ZC3H12A/DDX6/HAX1/TNRC6B/ZFP36L1/AICDA/DCP2/PSMA2/RC3H2/UPF1	13
CC	GO:0030670	phagocytic vesicle membrane	12/1674	76/19717	0.02592	0.4222	0.404	RAC2/SNAP23/DNM2/RAB9A/TAP1/HLA-H/IRGM/CORO1A/ATP6V0E1/HLA-A/HLA-C/RAB10	12
CC	GO:0000177	cytoplasmic exosome (RNase complex)	4/1674	14/19717	0.02596	0.4222	0.404	SUPV3L1/EXOSC5/DIS3/GTPBP1	4
CC	GO:0030677	ribonuclease P complex	4/1674	14/19717	0.02596	0.4222	0.404	RPP14/POP1/TRMT10C/RPP40	4
CC	GO:0032806	carboxy-terminal domain protein kinase complex	5/1674	21/19717	0.02827	0.4261	0.4078	CCNT1/GTF2H5/ERCC2/MNAT1/GTF2H4	5
CC	GO:0005770	late endosome	31/1674	256/19717	0.02842	0.4261	0.4078	MON1A/WDR48/GIMAP5/CXCR4/VPS37B/GRN/VPS18/WDR91/M6PR/NDFIP2/CTSH/NSG1/EXOC8/RAB9A/WDR81/BST2/IL12A/TSG101/IFITM3/RAPGEF2/CCZ1/DYNC1LI2/SLC38A9/CTNS/RAB27B/ABCA5/ABHD6/HTT/ATP13A2/LAMTOR2/SLC11A2	31
CC	GO:0030173	integral component of Golgi membrane	10/1674	60/19717	0.02863	0.4261	0.4078	TEX261/TBC1D20/SLC35A2/YIF1A/SLC35A4/SAMD8/CSGALNACT2/SYS1/MFNG/GALNT2	10
CC	GO:0031965	nuclear membrane	35/1674	296/19717	0.0287	0.4261	0.4078	CDK4/NUP50/TBC1D20/ZBTB1/WTAP/ANKRD17/SHISA5/HAX1/PLCB1/DDX19B/GCH1/NUP133/FAM169A/THAP7/PNPLA7/SLC30A1/AAAS/NUP35/SLC29A2/NUDT1/BCL2L1/CNEP1R1/TFPT/DHCR7/TNKS/SENP2/MAD2L1BP/GATA6/PHF20/SIGMAR1/RCC1/SPAG4/TOR1AIP1/PHLPP1/SIRT1	35
CC	GO:0000421	autophagosome membrane	7/1674	36/19717	0.02953	0.4291	0.4107	TM9SF1/SH3GLB1/ATG16L1/TEX264/WDR81/ATG14/IRGM	7
CC	GO:0001650	fibrillar center	18/1674	132/19717	0.03038	0.4322	0.4137	USO1/SPATA2/CD3EAP/NFKBIE/DUSP11/SMARCB1/ORC6/APEX2/RSAD2/MAP3K14/IP6K1/TIMM13/NFIC/NHEJ1/UTP15/NUAK1/DDX11/WDR33	18
CC	GO:0044455	mitochondrial membrane part	28/1674	229/19717	0.03217	0.4484	0.4292	NDUFS7/CISD1/MTX3/NDUFS2/GRPEL1/BDH1/NDUFA12/COA3/SCO1/MUL1/TOMM20L/SLC25A6/BCS1L/C15orf48/NDUFB8/SCO2/SLC25A4/BID/BNIP3/NDUFB11/NDUFB2/SLC25A19/TIMM10/COQ7/NDUFB10/RHOT2/CHCHD3/MPC1	28
CC	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane	4/1674	15/19717	0.03308	0.4518	0.4324	SPPL3/HM13/GNRH1/DNAJA1	4
CC	GO:0031463	Cul3-RING ubiquitin ligase complex	7/1674	37/19717	0.03384	0.4532	0.4338	PDCD6/KBTBD8/ENC1/KLHL21/SPOPL/GLMN/SPOP	7
CC	GO:0000502	proteasome complex	10/1674	63/19717	0.03863	0.5074	0.4856	PSME2/ZFAND2A/PSMD5/PSMA5/PSMA2/PSME4/VCP/PSMB3/UBE3A/PSMD2	10
CC	GO:0005811	lipid droplet	12/1674	81/19717	0.04016	0.5119	0.4899	DHRS3/TRAF6/PNPLA2/RSAD2/DFFA/SYNGR2/ATG2A/ACSL3/SIGMAR1/VCP/TSC1/LIPE	12
CC	GO:0034045	phagophore assembly site membrane	4/1674	16/19717	0.04122	0.5119	0.4899	ATG16L1/ATG14/ATG2A/RAB1B	4
CC	GO:0035098	ESC/E(Z) complex	4/1674	16/19717	0.04122	0.5119	0.4899	PHF1/HDAC2/JARID2/SIRT1	4
CC	GO:1905369	endopeptidase complex	10/1674	64/19717	0.04244	0.5176	0.4954	PSME2/ZFAND2A/PSMD5/PSMA5/PSMA2/PSME4/VCP/PSMB3/UBE3A/PSMD2	10
CC	GO:1902555	endoribonuclease complex	6/1674	31/19717	0.0434	0.5201	0.4978	RPP14/CLP1/POP1/DICER1/TRMT10C/RPP40	6
MF	GO:0019200	carbohydrate kinase activity	11/1629	21/17697	5.741e-07	0.0005862	0.0005717	NAGK/HK1/XYLB/FGGY/GALK2/PFKFB3/GALK1/HK2/PFKL/PFKFB4/PFKP	11
MF	GO:0140098	catalytic activity, acting on RNA	60/1629	386/17697	3.803e-05	0.01941	0.01893	ENDOG/POLR2J3/CD3EAP/RPP14/EDC3/DALRD3/TSEN15/POLR2D/DUS3L/RNASEH1/ZC3H12A/PCIF1/FDXACB1/DHX16/PRIM1/TRMT112/DDX6/SUPV3L1/POP1/TFB1M/NSUN4/POLR2H/DDX19B/DICER1/EIF4A2/METTL16/MED21/TRMT10C/EXOSC5/PUS1/DHX34/RRNAD1/DIS3/DARS2/TRPT1/DCP2/MRPL44/TRMT5/TRMT13/DDX54/TFB2M/FTO/TOE1/TGS1/DDX24/SLU7/WARS2/RAD54B/RPP40/CNOT6L/UPF1/ALKBH8/NSUN2/DDX58/TSN/REXO2/THUMPD2/ISG20/PUS3/DDX43	60
MF	GO:0035014	phosphatidylinositol 3-kinase regulator activity	8/1629	17/17697	5.762e-05	0.01961	0.01913	CISH/SOCS3/PIK3R1/WDR91/SOCS2/WDR81/KLF4/SOCS5	8
MF	GO:0048038	quinone binding	7/1629	17/17697	0.0004689	0.1195	0.1166	VKORC1/NDUFS7/VKORC1L1/NDUFS2/CBR4/COQ10B/DHODH	7
MF	GO:0009982	pseudouridine synthase activity	6/1629	13/17697	0.0005853	0.1195	0.1166	RPUSD2/PUSL1/RPUSD3/PUS1/TRUB1/PUS3	6
MF	GO:0008173	RNA methyltransferase activity	15/1629	66/17697	0.000798	0.1358	0.1324	PCIF1/FDXACB1/TRMT112/TFB1M/NSUN4/METTL16/TRMT10C/RRNAD1/TRMT5/TRMT13/TFB2M/TGS1/ALKBH8/NSUN2/THUMPD2	15
MF	GO:0050699	WW domain binding	9/1629	31/17697	0.001441	0.2101	0.2049	NDFIP2/DNM2/TNK2/RAPGEF2/WBP1/TP63/TCEAL3/PMEPA1/TRAF4	9
MF	GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	7/1629	21/17697	0.002018	0.2321	0.2263	PARP10/ZBTB1/ZRANB1/TNFAIP3/SPRTN/WDR81/ATRIP	7
MF	GO:0019207	kinase regulator activity	32/1629	207/17697	0.002488	0.2321	0.2263	CISH/CDK4/ABI1/CCNT1/RAC2/CCNJ/CCND3/DBF4/SOCS3/TRIB3/PIK3R1/PIK3CA/PRKAG2/WDR91/SOCS2/PRKRIP1/MNAT1/GMFB/CDKN2B/BCL10/CDKN1B/MBIP/SMCR8/WDR81/ETAA1/KLF4/CDKN2D/CCNL1/IRGM/DAXX/SOCS5/CDKN1A	32
MF	GO:0031072	heat shock protein binding	21/1629	119/17697	0.0027	0.2321	0.2263	GBP1/STIP1/CDK5/AHSA1/METTL23/FKBP4/CDKN1B/HSPA1A/DNAJB9/HDAC2/DNAJB1/UNC45A/PPEF2/DNAJA1/HSPA1L/TSC1/NR3C1/HSPA13/DAXX/HTT/APOA1	21
MF	GO:0008649	rRNA methyltransferase activity	7/1629	22/17697	0.002728	0.2321	0.2263	FDXACB1/TRMT112/TFB1M/NSUN4/METTL16/RRNAD1/TFB2M	7
MF	GO:0140102	catalytic activity, acting on a rRNA	7/1629	22/17697	0.002728	0.2321	0.2263	FDXACB1/TRMT112/TFB1M/NSUN4/METTL16/RRNAD1/TFB2M	7
MF	GO:0030674	protein binding, bridging	27/1629	170/17697	0.003551	0.2789	0.272	CUX1/PDCD6/TEX261/ERCC2/LAT/MEN1/HIP1R/PIK3R1/VPS18/SOCS2/FKBP4/RBM14/BFAR/AP2S1/FRS2/CLNK/SERINC1/DDB1/SH2B3/ARRDC4/HERPUD1/SKAP2/CDYL/SH2D3C/MAP1A/BIN3/ARHGAP4	27
MF	GO:0003713	transcription coactivator activity	44/1629	319/17697	0.004357	0.3177	0.3099	GMEB2/MED26/SERTAD2/DCAF6/TCERG1/CARM1/TAF11/SMARCB1/ABT1/JUND/JMY/NR1D2/CREBBP/MNT/ACTL6A/RBM14/ENY2/RXRB/PARK7/BCL10/MED21/NFKB2/JUNB/PRMT2/TBPL1/MTF1/CEBPA/TSG101/THRA/HTATIP2/MED6/EP300/RNF4/NR1D1/PQBP1/ASXL1/POU2AF1/PHF2/TADA1/ARID1B/UBE3A/USP16/DAXX/NCOA2	44
MF	GO:0047485	protein N-terminus binding	19/1629	109/17697	0.00482	0.3281	0.32	ERCC2/DCTN4/TAF11/MEN1/TRAF6/ALG2/MORF4L1/HAX1/PDCD10/MNAT1/THAP7/ZMYND8/HSPA1A/RPA2/GADD45A/MYO7A/MECP2/TSC1/DAXX	19
MF	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity	5/1629	14/17697	0.006475	0.3442	0.3357	CISH/SOCS3/PIK3R1/SOCS2/SOCS5	5
MF	GO:0002039	p53 binding	13/1629	66/17697	0.006491	0.3442	0.3357	EHMT2/CDK5/SMARCB1/CREBBP/RNF125/CDKN2AIP/EP300/BRD4/NUAK1/TP63/DAXX/HTT/SIRT1	13
MF	GO:0003714	transcription corepressor activity	34/1629	238/17697	0.006644	0.3442	0.3357	MXI1/TCERG1/PHF12/ZNF281/KCTD1/MIER1/CREBBP/CIR1/TRIB3/MXD1/MNT/CENPJ/ZMYND8/SIAH2/JUNB/HSPA1A/DNAJB1/TSG101/DDX54/ZNF274/MEIS2/TCP10L/NR1D1/ZHX2/MECP2/CDYL/ALX1/RLIM/DAXX/TOB2/KLF12/ARID5A/SIRT1/C1D	34
MF	GO:0008373	sialyltransferase activity	6/1629	20/17697	0.007536	0.3442	0.3357	ST6GAL1/ST6GALNAC4/ST3GAL3/ST3GAL5/ST3GAL2/ST6GALNAC1	6
MF	GO:0005085	guanyl-nucleotide exchange factor activity	31/1629	214/17697	0.00759	0.3442	0.3357	DENND6A/MON1A/RINL/RCBTB2/DENND4A/PTGIR/GDPGP1/VAV1/DOCK7/SMCR8/P2RY12/RALGPS1/DIS3/SOS1/EPS8L2/RANGRF/ARHGEF19/RAPGEF2/CCZ1/FBXO8/IQSEC2/ADRB1/KALRN/FNIP1/RCC1/SH2D3C/DENND1A/CYTH3/LAMTOR2/SBF2/FGD1	31
MF	GO:0051019	mitogen-activated protein kinase binding	7/1629	26/17697	0.007595	0.3442	0.3357	PRMT1/ATF7/MAPKAPK3/DUSP1/GCH1/MICALCL/SIRT1	7
MF	GO:0004674	protein serine/threonine kinase activity	56/1629	439/17697	0.007677	0.3442	0.3357	PIM1/STK16/CDK4/AAK1/PIM2/CDK5/IKBKB/ERCC2/CHEK2/CAMK2D/SIK1/PRKAB1/CCND3/STRADB/MAPKAPK3/AATK/RPS6KA1/MAP3K7/CDC42BPA/PIK3CA/PRKAG2/MAP3K3/TLK2/MAP3K14/MNAT1/GSK3A/CDK17/ACVR1B/MAPK11/SNRK/CSNK1E/STK36/PKN2/CLK4/CSNK1D/MASTL/TNK2/GTF2H4/PRKCE/RPS6KB2/LMTK2/STK33/BCKDK/BRD4/CAMK1D/STK35/KALRN/NUAK1/GRK6/LATS2/EIF2AK4/RAF1/PRKCI/PASK/MAPK6/TGFBR2	56
MF	GO:0061980	regulatory RNA binding	9/1629	39/17697	0.007753	0.3442	0.3357	ZC3H12A/NEAT1/ZC3H7A/DICER1/ELAVL1/RBM4/ZC3H10/MECP2/HNRNPA1	9
MF	GO:0001222	transcription corepressor binding	5/1629	15/17697	0.008986	0.3609	0.352	PER1/PHF12/RORA/PER3/NR1D1	5
MF	GO:0060590	ATPase regulator activity	9/1629	40/17697	0.009206	0.3609	0.352	GRPEL1/AHSA1/ATP1B2/DNAJB1/GTF2H4/FNIP1/DNAJA1/TOR1AIP1/TSC1	9
MF	GO:0016866	intramolecular transferase activity	7/1629	27/17697	0.009454	0.3609	0.352	RPUSD2/PGAM4/PUSL1/RPUSD3/PUS1/TRUB1/PUS3	7
MF	GO:0098505	G-rich strand telomeric DNA binding	4/1629	10/17697	0.009544	0.3609	0.352	TERF2IP/RPA2/HNRNPA1/RPA1	4
MF	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	10/1629	49/17697	0.0125	0.4559	0.4447	CDK4/CCNT1/CCNJ/CCND3/MNAT1/CDKN2B/CDKN1B/CDKN2D/CCNL1/CDKN1A	10
MF	GO:0001016	RNA polymerase III regulatory region DNA binding	4/1629	11/17697	0.01392	0.4656	0.4541	BRF2/BRF1/PRDX5/TBPL1	4
MF	GO:0070181	small ribosomal subunit rRNA binding	4/1629	11/17697	0.01392	0.4656	0.4541	MRPS18C/NSUN4/RBM3/UTP23	4
MF	GO:0051059	NF-kappaB binding	7/1629	29/17697	0.01414	0.4656	0.4541	HIF1AN/AKAP8/NFKBIA/BCL10/RNF25/HDAC2/EP300	7
MF	GO:0001221	transcription cofactor binding	9/1629	43/17697	0.0148	0.4723	0.4607	PER1/MAFK/PHF12/NFE2L2/RORA/KLF4/PER3/NR1D1/CHD6	9
MF	GO:0016741	transferase activity, transferring one-carbon groups	31/1629	226/17697	0.01602	0.4881	0.476	GART/PRMT1/EHMT2/CARM1/METTL23/MEN1/PCIF1/FDXACB1/TRMT112/TFB1M/PRDM4/NSUN4/SMYD5/NSUN5P2/METTL16/TRMT10C/PRMT2/NTMT1/ASH1L/FAM98B/RRNAD1/TRMT5/INMT/TRMT13/TFB2M/TGS1/SETD1B/CAD/ALKBH8/NSUN2/THUMPD2	31
MF	GO:0004540	ribonuclease activity	18/1629	114/17697	0.01625	0.4881	0.476	ENDOG/RPP14/EDC3/TSEN15/RNASEH1/ZC3H12A/POP1/DICER1/EXOSC5/DIS3/DCP2/MRPL44/TOE1/RPP40/CNOT6L/TSN/REXO2/ISG20	18
MF	GO:0060090	molecular adaptor activity	32/1629	237/17697	0.018	0.5063	0.4938	CUX1/PDCD6/TEX261/ERCC2/LAT/MEN1/HIP1R/PIK3R1/VPS18/SOCS2/FKBP4/RBM14/BFAR/AP2S1/FRS2/CLNK/SERINC1/DDB1/SH2B3/OTUD4/ARRDC4/HERPUD1/MAPK8IP3/SKAP2/CDYL/SH2D3C/MAP1A/MPP7/BIN3/CHCHD3/ARHGAP4/LAMTOR2	32
MF	GO:0003779	actin binding	53/1629	431/17697	0.01812	0.5063	0.4938	GBP1/PPP1R18/MYH10/CAMSAP3/CFL2/SYN1/JMY/CXCR4/HIP1R/CTNNAL1/WHAMM/ARPC1B/WDR1/CEACAM1/VPS18/PDLIM2/MYO16/VASH1/TIGD5/MYO1E/DIXDC1/ENC1/GMFB/SPIRE2/TNNT3/TNNC2/NOS3/TWF2/PALLD/VASP/CAPZB/CORO1B/HOMER2/EPS8L2/CFL1/PRKCE/PSTPIP2/MYO7A/TWF1/NEXN/EPB41L2/TMSB4Y/MYO5C/CORO1A/MYOM2/CCDC88A/MYH7B/WASL/MAP1A/CNN2/FMN1/ARPC5/GAS2L3	53
MF	GO:0051213	dioxygenase activity	15/1629	91/17697	0.01866	0.5063	0.4938	EGLN2/HIF1AN/ADO/EGLN3/KDM2A/HPDL/ETHE1/PTGS1/FTO/PHF2/HGD/BCO2/ALKBH8/TET1/KDM8	15
MF	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	4/1629	12/17697	0.01938	0.5063	0.4938	CDKN2B/CDKN1B/CDKN2D/CDKN1A	4
MF	GO:0043047	single-stranded telomeric DNA binding	4/1629	12/17697	0.01938	0.5063	0.4938	TERF2IP/RPA2/HNRNPA1/RPA1	4
MF	GO:0035198	miRNA binding	7/1629	31/17697	0.02027	0.5063	0.4938	ZC3H12A/NEAT1/ZC3H7A/ELAVL1/RBM4/ZC3H10/HNRNPA1	7
MF	GO:0004532	exoribonuclease activity	8/1629	38/17697	0.02033	0.5063	0.4938	ZC3H12A/EXOSC5/DIS3/DCP2/TOE1/CNOT6L/REXO2/ISG20	8