ONTOLOGY	ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	qvalue	geneID	Count
KEGG	hsa05168	Herpes simplex virus 1 infection	75/727	495/8135	2.461e-06	0.0007899	0.0006735	IRF7/ZNF404/ZNF74/NFKBIA/ZNF708/IKBKB/ZNF793/ZNF552/ZNF766/ZNF257/ZNF107/ZNF155/ZNF211/ZNF420/ZNF175/ZNF8/ZNF546/TRAF6/SOCS3/ZNF350/CASP9/ZNF529/PIK3R1/OAS2/ZNF160/MAP3K7/ZNF7/PIK3CA/ZNF616/ZNF599/RBAK/ZNF331/ZNF585A/ZNF212/ZNF251/ZNF177/ZNF12/ZNF419/ZNF250/ZNF615/ZNF829/FADD/ZNF689/ZNF790/BID/ZNF26/ZNF436/BCL2L1/ZNF90/TAP1/BST2/ZNF718/ZNF627/IL12A/ZNF568/ZNF570/ZNF135/ZNF490/ZNF33B/ZNF805/HLA-A/IFNA10/ZNF256/TSC1/ZNF510/EIF2AK4/ZNF578/ZNF530/DDX58/DAXX/HLA-C/OAS1/ZNF780A/C5/ZNF432	75
KEGG	hsa04068	FoxO signaling pathway	26/727	131/8135	7.683e-05	0.007986	0.006809	PRMT1/IKBKB/PRKAB1/CREBBP/PIK3R1/PIK3CA/PRKAG2/TNFSF10/CDKN2B/CDKN1B/MAPK11/CSNK1E/AGAP2/BNIP3/CDKN2D/HOMER2/GADD45A/SOS1/EP300/IRS2/SKP2/RAF1/BCL6/CDKN1A/SIRT1/TGFBR2	26
KEGG	hsa05162	Measles	27/727	139/8135	8.294e-05	0.007986	0.006809	CDK4/IRF7/NFKBIA/IKBKB/TRAF6/CCND3/TNFAIP3/CASP9/PIK3R1/OAS2/MAP3K7/PIK3CA/CDKN1B/FADD/HSPA1A/BID/RAB9A/BCL2L1/IL12A/CD46/CBLB/JAK3/HSPA1L/IFNA10/EIF2AK4/DDX58/OAS1	27
KEGG	hsa05164	Influenza A	31/727	171/8135	9.952e-05	0.007986	0.006809	CDK4/IRF7/NFKBIA/IKBKB/FDPS/ACTG1/TNFRSF10B/PYCARD/CCND3/SOCS3/KPNA5/CREBBP/RSAD2/CASP9/SLC25A6/PIK3R1/OAS2/PIK3CA/ACTB/TNFSF10/FADD/SLC25A4/BID/DNAJB1/IL12A/HNRNPUL1/EP300/IFNA10/RAF1/DDX58/OAS1	31
KEGG	hsa05169	Epstein-Barr virus infection	34/727	202/8135	0.0002108	0.01274	0.01086	CDK4/IRF7/NFKBIE/NFKBIA/IKBKB/ISG15/TRAF6/CCND3/TNFAIP3/CASP9/CIR1/PIK3R1/OAS2/MAP3K7/PIK3CA/MAP3K14/MYC/CDKN1B/MAPK11/FADD/NFKB2/BID/HDAC2/TAP1/GADD45A/JAK3/HLA-A/IFNA10/SKP2/DDX58/HLA-C/OAS1/CDKN1A/PSMD2	34
KEGG	hsa04710	Circadian rhythm	10/727	31/8135	0.0002381	0.01274	0.01086	PER1/CRY2/PRKAB1/PRKAG2/RORA/CSNK1E/CSNK1D/FBXL3/PER3/NR1D1	10
KEGG	hsa05134	Legionellosis	14/727	57/8135	0.0003701	0.01697	0.01447	NFKBIA/PYCARD/TLR5/CASP9/SAR1A/NFKB2/CLK4/HSPA1A/BNIP3/IL12A/VCP/HSPA1L/RAB1B/CASP7	14
KEGG	hsa04919	Thyroid hormone signaling pathway	22/727	121/8135	0.0009459	0.03796	0.03236	NOTCH1/ACTG1/CREBBP/CASP9/PIK3R1/PIK3CA/PLCB1/MYC/ATP2A1/RXRB/ACTB/BMP4/MED13L/ATP1B2/HDAC2/SLC2A1/THRA/EP300/PFKL/RAF1/PFKP/NCOA2	22
KEGG	hsa04210	Apoptosis	23/727	136/8135	0.002009	0.06456	0.05504	ENDOG/NFKBIA/IKBKB/ACTG1/TNFRSF10B/CASP9/DFFA/PIK3R1/PIK3CA/MAP3K14/CASP10/CTSH/ACTB/TNFSF10/FADD/BID/BCL2L1/GADD45A/CTSK/ATF4/RAF1/DAXX/CASP7	23
KEGG	hsa04152	AMPK signaling pathway	21/727	120/8135	0.002011	0.06456	0.05504	CPT1B/CPT1C/PRKAB1/STRADB/ADIPOR2/PIK3R1/MAP3K7/PIK3CA/PRKAG2/AKT1S1/ELAVL1/PFKFB3/RPS6KB2/IRS2/PFKL/TSC1/LIPE/PFKFB4/PFKP/RAB10/SIRT1	21
KEGG	hsa01230	Biosynthesis of amino acids	15/727	75/8135	0.002263	0.06603	0.05629	PSAT1/PGAM4/MAT2B/BCAT1/ACY1/TKTL1/TALDO1/PSPH/ALDH18A1/PGK2/MAT2A/PFKL/ASS1/CTH/PFKP	15
KEGG	hsa05132	Salmonella infection	36/727	249/8135	0.002502	0.06693	0.05707	ABI1/NFKBIA/IKBKB/ACTG1/DCTN4/TNFRSF10B/PYCARD/TLR5/TRAF6/TUBB6/ARPC1B/DYNLRB1/MAP3K7/PIK3CA/VPS18/M6PR/TCF7L2/MYC/ACTB/TNFSF10/FBXO22/MAPK11/DNM2/FADD/RAB9A/DYNLT1/DYNC1LI2/CSE1L/WASL/DYNLL1/MYL12A/RAF1/NCKAP1/CYTH3/ARPC5/CASP7	36
KEGG	hsa05222	Small cell lung cancer	17/727	92/8135	0.0029	0.0716	0.06104	CDK4/NFKBIA/IKBKB/TRAF6/CASP9/PIK3R1/PIK3CA/MYC/RXRB/CDKN2B/CDKN1B/BCL2L1/GADD45A/ITGA3/SKP2/CDKN1A/TRAF4	17
KEGG	hsa04066	HIF-1 signaling pathway	19/727	109/8135	0.003374	0.07736	0.06596	EGLN2/HK1/EGLN3/CAMK2D/PDHA1/CREBBP/PIK3R1/PIK3CA/CDKN1B/NOS3/SLC2A1/PFKFB3/RPS6KB2/PGK2/EP300/HK2/PFKL/PFKP/CDKN1A	19
KEGG	hsa05161	Hepatitis B	25/727	162/8135	0.004679	0.1001	0.08538	IRF7/NFKBIA/IKBKB/TRAF6/CREBBP/CASP9/PIK3R1/MAP3K7/PIK3CA/CASP10/MYC/MAPK11/FADD/BID/DDB1/SOS1/YWHAZ/EP300/ATF4/JAK3/IFNA10/RAF1/DDX58/CDKN1A/TGFBR2	25
KEGG	hsa05160	Hepatitis C	24/727	157/8135	0.006221	0.1065	0.09079	CDK4/IRF7/CLDN15/NFKBIA/IKBKB/IFIT1/TRAF6/SOCS3/RSAD2/CASP9/PIK3R1/OAS2/PIK3CA/MYC/FADD/BID/SOS1/YWHAZ/IFNA10/EIF2AK4/RAF1/DDX58/OAS1/CDKN1A	24
KEGG	hsa04922	Glucagon signaling pathway	18/727	107/8135	0.006258	0.1065	0.09079	CPT1B/PRMT1/CPT1C/PGAM4/CAMK2D/SIK1/PRKAB1/PDHA1/CREBBP/PRKAG2/PLCB1/CALML4/SLC2A1/EP300/ATF4/PFKL/PFKP/SIRT1	18
KEGG	hsa04930	Type II diabetes mellitus	10/727	46/8135	0.006419	0.1065	0.09079	HK1/IKBKB/SOCS4/SOCS3/PIK3R1/PIK3CA/SOCS2/PRKCE/HK2/IRS2	10
KEGG	hsa05220	Chronic myeloid leukemia	14/727	76/8135	0.006758	0.1065	0.09079	CDK4/NFKBIA/IKBKB/PIK3R1/PIK3CA/MYC/CDKN1B/HDAC2/BCL2L1/GADD45A/SOS1/RAF1/CDKN1A/TGFBR2	14
KEGG	hsa04931	Insulin resistance	18/727	108/8135	0.006903	0.1065	0.09079	CPT1B/NFKBIA/IKBKB/PPP1R3D/PRKAB1/SOCS3/TRIB3/RPS6KA1/PIK3R1/PIK3CA/PRKAG2/GFPT2/SLC27A4/NOS3/SLC2A1/PRKCE/RPS6KB2/IRS2	18
KEGG	hsa04920	Adipocytokine signaling pathway	13/727	69/8135	0.007335	0.1065	0.09079	CPT1B/NFKBIE/NFKBIA/IKBKB/CPT1C/PRKAB1/SOCS3/ADIPOR2/PRKAG2/RXRB/SLC2A1/ACSL3/IRS2	13
KEGG	hsa04213	Longevity regulating pathway - multiple species	12/727	62/8135	0.00789	0.1065	0.09079	PRKAB1/PIK3R1/PIK3CA/PRKAG2/CLPB/HSPA1A/AKT1S1/HDAC2/RPS6KB2/IRS2/HSPA1L/SIRT1	12
KEGG	hsa04110	Cell cycle	20/727	126/8135	0.007901	0.1065	0.09079	CDK4/STAG2/ORC6/CHEK2/CCND3/DBF4/CREBBP/MYC/CDKN2B/CDKN1B/ANAPC7/HDAC2/CDKN2D/GADD45A/YWHAZ/EP300/TFDP2/SKP2/CDC25B/CDKN1A	20
KEGG	hsa04622	RIG-I-like receptor signaling pathway	13/727	70/8135	0.008294	0.1065	0.09079	IRF7/NFKBIA/IKBKB/ISG15/TRAF6/MAP3K7/CASP10/MAPK11/FADD/IL12A/RNF125/IFNA10/DDX58	13
KEGG	hsa05230	Central carbon metabolism in cancer	13/727	70/8135	0.008294	0.1065	0.09079	HK1/PGAM4/PDHA1/PIK3R1/SLC1A5/PIK3CA/MYC/SCO2/SLC2A1/HK2/PFKL/RAF1/PFKP	13
KEGG	hsa04218	Cellular senescence	23/727	156/8135	0.0112	0.1383	0.1179	CDK4/CHEK2/CCND3/SLC25A6/PIK3R1/PIK3CA/MYC/CDKN2B/MAPK11/SLC25A4/ZFP36L1/CALML4/GADD45A/ZFP36L2/HLA-A/TSC1/RAF1/HLA-C/LIN54/CDKN1A/SIRT1/TGFBR2/RRAS2	23
KEGG	hsa04115	p53 signaling pathway	13/727	73/8135	0.01177	0.1399	0.1193	CDK4/GORAB/TNFRSF10B/CHEK2/CCND3/THBS1/CASP9/SHISA5/SIVA1/BID/BCL2L1/GADD45A/CDKN1A	13
KEGG	hsa00130	Ubiquinone and other terpenoid-quinone biosynthesis	4/727	11/8135	0.01253	0.1436	0.1224	VKORC1/VKORC1L1/GGCX/COQ7	4
KEGG	hsa04662	B cell receptor signaling pathway	14/727	82/8135	0.01315	0.1456	0.1241	PTPN6/NFKBIE/RAC2/NFKBIA/IKBKB/CD79B/PIK3R1/PIK3CA/VAV1/BCL10/IFITM1/SOS1/LILRB3/RAF1	14
KEGG	hsa01250	Biosynthesis of nucleotide sugars	8/727	37/8135	0.01465	0.1526	0.1301	NAGK/HK1/UGDH/GFPT2/GALK2/GALK1/GALT/HK2	8
KEGG	hsa04714	Thermogenesis	31/727	232/8135	0.01474	0.1526	0.1301	CPT1B/NDUFS7/COA5/CPT1C/ACTG1/NDUFS2/SMARCB1/NDUFA12/COA3/PRKAB1/PNPLA2/RPS6KA1/PRKAG2/ACTL6A/NDUFB8/ACTB/SLC25A20/MAPK11/FRS2/AKT1S1/NDUFAF3/SOS1/COX19/NDUFB11/NDUFB2/RPS6KB2/ACSL3/NDUFB10/TSC1/ARID1B/LIPE	31
KEGG	hsa05130	Pathogenic Escherichia coli infection	27/727	197/8135	0.01613	0.1618	0.138	ABI1/PTPN6/CLDN15/NFKBIA/IKBKB/MYH10/ACTG1/TNFRSF10B/PYCARD/TLR5/TRAF6/TUBB6/CASP9/ARPC1B/MAP3K7/MYO1E/ACTB/TNFSF10/MAPK11/FADD/MYO5C/LPAR2/WASL/NCKAP1/CYTH3/ARPC5/CASP7	27
KEGG	hsa01240	Biosynthesis of cofactors	22/727	153/8135	0.01699	0.1653	0.1409	PSAT1/VKORC1/DHRS3/VKORC1L1/MAT2B/RFK/BCAT1/UGDH/GCH1/DHFR/ASPDH/MTHFD2L/GGCX/MAT2A/DHODH/COQ7/CAD/MTHFD1L/PNPO/DLD/ALAD/AK3	22
KEGG	hsa04722	Neurotrophin signaling pathway	18/727	119/8135	0.01819	0.1717	0.1464	NFKBIE/NFKBIA/IKBKB/CAMK2D/TRAF6/RPS6KA1/PIK3R1/PIK3CA/PRDM4/MAP3K3/MAPK11/FRS2/SH2B3/CALML4/SOS1/ZNF274/ATF4/RAF1	18
KEGG	hsa04910	Insulin signaling pathway	20/727	137/8135	0.01907	0.1749	0.1491	HK1/IKBKB/PPP1R3D/PRKAB1/SOCS4/SOCS3/PIK3R1/PIK3CA/PRKAG2/SOCS2/CALML4/SOS1/RPS6KB2/CBLB/HK2/IRS2/TSC1/LIPE/RAF1/PRKCI	20
KEGG	hsa03420	Nucleotide excision repair	9/727	47/8135	0.02148	0.1803	0.1537	POLD2/GTF2H5/ERCC2/POLD4/MNAT1/RPA2/DDB1/GTF2H4/RPA1	9
KEGG	hsa04660	T cell receptor signaling pathway	16/727	104/8135	0.02165	0.1803	0.1537	CDK4/PTPN6/NFKBIE/NFKBIA/IKBKB/LAT/PIK3R1/MAP3K7/PIK3CA/MAP3K14/VAV1/BCL10/MAPK11/SOS1/CBLB/RAF1	16
KEGG	hsa03018	RNA degradation	13/727	79/8135	0.022	0.1803	0.1537	EDC3/DCP1A/DDX6/EXOSC5/BTG2/DIS3/DCP2/PFKL/WDR61/CNOT6L/PFKP/TOB2/C1D	13
KEGG	hsa04520	Adherens junction	12/727	71/8135	0.0224	0.1803	0.1537	PTPN6/RAC2/ACTG1/YES1/CREBBP/MAP3K7/TCF7L2/ACTB/EP300/CTNND1/WASL/TGFBR2	12
KEGG	hsa03250	Viral life cycle - HIV-1	11/727	63/8135	0.02252	0.1803	0.1537	SERINC3/CCNT1/SMARCB1/CXCR4/CREBBP/PDCD6IP/BST2/TSG101/EP300/MAP1A/ELL2	11
KEGG	hsa05166	Human T-cell leukemia virus 1 infection	29/727	222/8135	0.02369	0.1803	0.1537	CDK4/NFKBIA/IKBKB/SRF/FDPS/CHEK2/CCND3/CREBBP/POLB/SLC25A6/PIK3R1/PIK3CA/MAP3K3/MAP3K14/MYC/CDKN2B/ANAPC7/NFKB2/SLC25A4/BCL2L1/TBPL1/SLC2A1/EP300/ATF4/JAK3/HLA-A/HLA-C/CDKN1A/TGFBR2	29
KEGG	hsa00051	Fructose and mannose metabolism	7/727	33/8135	0.02415	0.1803	0.1537	HK1/SORD/PFKFB3/HK2/PFKL/PFKFB4/PFKP	7
KEGG	hsa03410	Base excision repair	7/727	33/8135	0.02415	0.1803	0.1537	POLD2/POLL/APEX2/POLD4/POLB/XRCC1/SMUG1	7
KEGG	hsa04140	Autophagy - animal	20/727	141/8135	0.02531	0.1846	0.1574	NRBF2/TRAF6/SH3GLB1/PIK3R1/MAP3K7/PIK3CA/ATG16L1/SMCR8/MTMR14/AKT1S1/BNIP3/BCL2L1/ATG14/ATG2A/RPS6KB2/IRS2/TSC1/EIF2AK4/RAF1/RRAS2	20
KEGG	hsa05417	Lipid and atherosclerosis	28/727	215/8135	0.02685	0.1915	0.1633	IRF7/NFKBIA/IKBKB/TNFRSF10B/CAMK2D/PYCARD/TRAF6/NFE2L2/CASP9/PIK3R1/MAP3K7/PIK3CA/PLCB1/RXRB/VAV1/TNFSF10/MAPK11/HSPA1A/BID/NOS3/BCL2L1/IL12A/CALML4/ATF4/HSPA1L/IFNA10/APOA1/CASP7	28
KEGG	hsa00520	Amino sugar and nucleotide sugar metabolism	9/727	49/8135	0.02763	0.1918	0.1636	NAGK/HK1/UGDH/GNPDA1/GFPT2/GALK2/GALK1/GALT/HK2	9
KEGG	hsa00670	One carbon pool by folate	5/727	20/8135	0.02809	0.1918	0.1636	GART/MTHFS/DHFR/MTHFD2L/MTHFD1L	5
KEGG	hsa04146	Peroxisome	13/727	82/8135	0.02909	0.1945	0.1659	HMGCL/PEX12/PMVK/MVK/PEX6/PRDX5/MPV17/PEX16/PEX11B/PECR/DHRS4/ACSL3/NUDT19	13
KEGG	hsa04630	JAK-STAT signaling pathway	22/727	162/8135	0.03068	0.201	0.1714	CISH/PIM1/PTPN6/CCND3/SOCS4/SOCS3/CREBBP/PIK3R1/PIK3CA/SOCS2/MYC/CRLF2/BCL2L1/IL12A/SOS1/IL27RA/EP300/JAK3/IFNA10/RAF1/SOCS5/CDKN1A	22
KEGG	hsa05221	Acute myeloid leukemia	11/727	67/8135	0.03404	0.2177	0.1856	PIM1/PIM2/IKBKB/PIK3R1/PIK3CA/TCF7L2/MYC/CEBPA/SOS1/RPS6KB2/RAF1	11
KEGG	hsa04932	Non-alcoholic fatty liver disease	21/727	155/8135	0.03494	0.2177	0.1856	NDUFS7/IKBKB/NDUFS2/NDUFA12/PRKAB1/SOCS3/ADIPOR2/PIK3R1/PIK3CA/PRKAG2/GSK3A/NDUFB8/MAPK11/BID/CEBPA/NDUFB11/NDUFB2/ATF4/IRS2/NDUFB10/CASP7	21
KEGG	hsa05135	Yersinia infection	19/727	137/8135	0.03527	0.2177	0.1856	RAC2/NFKBIA/IKBKB/ACTG1/LAT/PYCARD/TRAF6/ARPC1B/RPS6KA1/PIK3R1/MAP3K7/PIK3CA/VAV1/ACTB/MAPK11/PKN2/SKAP2/WASL/ARPC5	19
KEGG	hsa05212	Pancreatic cancer	12/727	76/8135	0.03615	0.219	0.1867	CDK4/RAC2/IKBKB/CASP9/PIK3R1/PIK3CA/BCL2L1/GADD45A/RPS6KB2/RAF1/CDKN1A/TGFBR2	12
KEGG	hsa05167	Kaposi sarcoma-associated herpesvirus infection	25/727	194/8135	0.03911	0.2325	0.1982	CDK4/IRF7/NFKBIA/IKBKB/GNG4/CREBBP/CASP9/PIK3R1/PIK3CA/TCF7L2/MYC/MAPK11/FADD/GNG8/BID/ATG14/CALML4/MICA/EP300/MICB/HLA-A/IFNA10/RAF1/HLA-C/CDKN1A	25
KEGG	hsa05203	Viral carcinogenesis	26/727	204/8135	0.04037	0.2356	0.2009	CDK4/IRF7/NFKBIA/SRF/CCND3/CREBBP/POLB/PIK3R1/PIK3CA/REL/CDKN2B/CDKN1B/NFKB2/HDAC2/TBPL1/DDB1/GTF2H4/YWHAZ/EP300/ATF4/JAK3/HLA-A/SKP2/UBE3A/HLA-C/CDKN1A	26
KEGG	hsa05225	Hepatocellular carcinoma	22/727	168/8135	0.04361	0.2459	0.2096	CDK4/ACTG1/SMARCB1/FZD6/FRAT1/NFE2L2/PIK3R1/PIK3CA/GSTM4/ACTL6A/TCF7L2/MYC/ACTB/BCL2L1/GADD45A/SOS1/RPS6KB2/WNT10B/ARID1B/RAF1/CDKN1A/TGFBR2	22
KEGG	hsa03022	Basal transcription factors	8/727	45/8135	0.04366	0.2459	0.2096	GTF2H5/ERCC2/TAF11/MNAT1/TBPL1/GTF2H4/TAF15/TAF13	8
KEGG	hsa04917	Prolactin signaling pathway	11/727	70/8135	0.04503	0.2492	0.2125	CISH/SOCS4/SOCS3/PIK3R1/PIK3CA/SOCS2/MAPK11/SOS1/GALT/RAF1/SOCS5	11
KEGG	hsa03460	Fanconi anemia pathway	9/727	54/8135	0.04817	0.2566	0.2188	WDR48/FANCE/RPA2/FANCC/RMI2/RPA1/MUS81/TOP3B/ATRIP	9
KEGG	hsa04666	Fc gamma R-mediated phagocytosis	14/727	97/8135	0.04877	0.2566	0.2188	RAC2/CFL2/LAT/ARPC1B/PIK3R1/PIK3CA/VAV1/DNM2/VASP/CFL1/PRKCE/RPS6KB2/RAF1/ARPC5	14
KEGG	hsa05215	Prostate cancer	14/727	97/8135	0.04877	0.2566	0.2188	NFKBIA/IKBKB/CREBBP/CASP9/PIK3R1/PIK3CA/TCF7L2/CDKN1B/SOS1/EP300/ATF4/RAF1/CDKN1A/PDGFC	14
KEGG	hsa05131	Shigellosis	30/727	247/8135	0.05079	0.2629	0.2242	HK1/NFKBIA/IKBKB/ACTG1/PYCARD/TLR5/TRAF6/ARPC1B/PIK3R1/MAP3K7/PIK3CA/ATG16L1/PLCB1/GSK3A/ACTB/BCL10/MAPK11/AKT1S1/BNIP3/BCL2L1/RBCK1/ATG14/GLMN/PRKCE/RPS6KB2/HK2/WASL/MYL12A/CYTH3/ARPC5	30
KEGG	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	13/727	89/8135	0.05186	0.2634	0.2246	PTPN6/NFKBIE/NFKBIA/IKBKB/BATF/LAT/TRAF6/PIK3R1/PIK3CA/MAP3K3/MAPK11/RPS6KB2/RAF1	13
KEGG	hsa00920	Sulfur metabolism	3/727	10/8135	0.05298	0.2634	0.2246	ETHE1/IMPAD1/BPNT1	3
KEGG	hsa00052	Galactose metabolism	6/727	31/8135	0.05334	0.2634	0.2246	HK1/GALK1/GALT/HK2/PFKL/PFKP	6
KEGG	hsa05170	Human immunodeficiency virus 1 infection	26/727	212/8135	0.05962	0.29	0.2472	RAC2/NFKBIA/IKBKB/GNG4/CFL2/CXCR4/TRAF6/CASP9/PIK3R1/MAP3K7/PIK3CA/MAPK11/FADD/GNG8/BID/BCL2L1/TAP1/BST2/DDB1/CALML4/CFL1/RPS6KB2/HLA-A/IFNA10/RAF1/HLA-C	26
KEGG	hsa04150	mTOR signaling pathway	20/727	156/8135	0.06293	0.2989	0.2548	IKBKB/FZD6/STRADB/TTI1/RPS6KA1/PIK3R1/PIK3CA/RICTOR/AKT1S1/SOS1/RPS6KB2/ATP6V1G1/WDR24/SLC38A9/WNT10B/FNIP1/TSC1/SKP2/RAF1/LAMTOR2	20
KEGG	hsa05165	Human papillomavirus infection	38/727	331/8135	0.06332	0.2989	0.2548	CDK4/NOTCH1/IKBKB/FZD6/COL6A2/ISG15/CCND3/CREBBP/THBS1/PIK3R1/PIK3CA/MPP5/THBS3/TCF7L2/ITGA10/CDKN1B/FADD/HDAC2/VTN/TBPL1/SOS1/ITGA3/PARD6G/RPS6KB2/ATP6V1G1/EP300/MFNG/ATP6V0E1/WNT10B/COL1A1/HLA-A/IFNA10/TSC1/UBE3A/RAF1/PRKCI/HLA-C/CDKN1A	38
KEGG	hsa03040	Spliceosome	19/727	147/8135	0.06425	0.2989	0.2549	HNRNPA1L2/TCERG1/RBM25/SNRPA1/DHX16/SF3A1/CHERP/HSPA1A/SF3A2/RP9/PPIL1/SLU7/PQBP1/PHF5A/SRSF10/XAB2/HNRNPA1/HSPA1L/RBM17	19
KEGG	hsa03440	Homologous recombination	7/727	41/8135	0.06874	0.3141	0.2678	POLD2/POLD4/RPA2/RAD54B/RPA1/MUS81/TOP3B	7
KEGG	hsa04010	MAPK signaling pathway	34/727	294/8135	0.06994	0.3141	0.2678	RAC2/IKBKB/SRF/DUSP8/PPM1B/JUND/TRAF6/MAPKAPK3/DUSP1/RPS6KA1/MAP3K7/MAP3K3/MAP3K14/CACNA2D4/MYC/MAPK11/NFKB2/FLT4/HSPA1A/GADD45A/SOS1/RAPGEF2/MAPK8IP3/ATF4/FGF9/HSPA1L/PPM1A/CDC25B/RAF1/DAXX/DUSP7/PDGFC/TGFBR2/RRAS2	34
KEGG	hsa05213	Endometrial cancer	9/727	58/8135	0.07046	0.3141	0.2678	CASP9/PIK3R1/PIK3CA/TCF7L2/MYC/GADD45A/SOS1/RAF1/CDKN1A	9
KEGG	hsa04668	TNF signaling pathway	15/727	112/8135	0.07284	0.3203	0.2731	NFKBIA/IKBKB/SOCS3/TNFAIP3/PIK3R1/MAP3K7/PIK3CA/MAP3K14/CASP10/MAPK11/FADD/JUNB/MMP14/ATF4/CASP7	15
KEGG	hsa04650	Natural killer cell mediated cytotoxicity	17/727	131/8135	0.07473	0.3242	0.2764	PTPN6/RAC2/TNFRSF10B/LAT/PIK3R1/PIK3CA/VAV1/TNFSF10/BID/SOS1/MICA/MICB/HLA-A/IFNA10/RAF1/KIR2DL1/HLA-C	17
KEGG	hsa00563	Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	5/727	26/8135	0.07673	0.3271	0.2789	PIGA/PIGH/MPPE1/PIGL/GPAA1	5
KEGG	hsa04810	Regulation of actin cytoskeleton	26/727	218/8135	0.07782	0.3271	0.2789	RAC2/MYH10/ACTG1/CFL2/CXCR4/ARPC1B/PIK3R1/PIK3CA/VAV1/ITGA10/ACTB/SOS1/ITGA3/CFL1/CHRM4/TMSB4Y/LPAR2/FGF9/WASL/MYL12A/RAF1/NCKAP1/ARPC5/FGD1/PDGFC/RRAS2	26
KEGG	hsa04625	C-type lectin receptor signaling pathway	14/727	104/8135	0.07846	0.3271	0.2789	NFKBIA/IKBKB/PYCARD/PIK3R1/PIK3CA/MAP3K14/BCL10/MAPK11/NFKB2/IL12A/CALML4/CBLB/RAF1/RRAS2	14
KEGG	hsa05210	Colorectal cancer	12/727	86/8135	0.07962	0.3277	0.2794	RAC2/CASP9/PIK3R1/PIK3CA/TCF7L2/MYC/GADD45A/SOS1/RPS6KB2/RAF1/CDKN1A/TGFBR2	12
KEGG	hsa05211	Renal cell carcinoma	10/727	69/8135	0.08504	0.3424	0.292	EGLN2/EGLN3/CREBBP/PIK3R1/PIK3CA/SLC2A1/SOS1/EP300/RAF1/CDKN1A	10
KEGG	hsa04611	Platelet activation	16/727	124/8135	0.08534	0.3424	0.292	ACTG1/PIK3R1/SNAP23/PTGIR/PIK3CA/PLCB1/ACTB/MAPK11/P2RY12/NOS3/VASP/PTGS1/FERMT3/COL1A1/MYL12A/PRKCI	16
KEGG	hsa04144	Endocytosis	29/727	251/8135	0.08959	0.3551	0.3027	CXCR4/TRAF6/ARPC1B/VPS37B/SH3GLB1/PDCD6IP/AP2S1/DNM2/HSPA1A/SMURF1/AGAP2/CAPZB/RAB11FIP2/TSG101/ACAP1/PARD6G/CBLB/ARAP1/IQSEC2/GRK6/HSPA1L/HLA-A/WASL/PRKCI/HLA-C/RAB10/CYTH3/ARPC5/TGFBR2	29
KEGG	hsa05415	Diabetic cardiomyopathy	24/727	203/8135	0.09434	0.3673	0.3131	CPT1B/NDUFS7/RAC2/NDUFS2/CAMK2D/NDUFA12/PDHA1/SLC25A6/PIK3R1/PIK3CA/PLCB1/ATP2A1/NDUFB8/GFPT2/MAPK11/SLC25A4/NOS3/SLC2A1/NDUFB11/NDUFB2/COL1A1/NDUFB10/MPC1/TGFBR2	24
KEGG	hsa01522	Endocrine resistance	13/727	98/8135	0.09585	0.3673	0.3131	CDK4/HBEGF/NOTCH1/CARM1/PIK3R1/PIK3CA/CYP2D6/CDKN1B/MAPK11/SOS1/RPS6KB2/RAF1/CDKN1A	13
KEGG	hsa03030	DNA replication	6/727	36/8135	0.09715	0.3673	0.3131	POLD2/RNASEH1/POLD4/PRIM1/RPA2/RPA1	6
KEGG	hsa04211	Longevity regulating pathway	12/727	89/8135	0.09726	0.3673	0.3131	EHMT2/PRKAB1/ADIPOR2/PIK3R1/PIK3CA/PRKAG2/AKT1S1/RPS6KB2/ATF4/IRS2/TSC1/SIRT1	12
KEGG	hsa05163	Human cytomegalovirus infection	26/727	225/8135	0.1034	0.3861	0.3292	CDK4/RAC2/NFKBIA/IKBKB/GNG4/CXCR4/CASP9/PIK3R1/PIK3CA/PLCB1/MYC/MAPK11/FADD/GNG8/BID/TAP1/CALML4/SOS1/RPS6KB2/ATF4/HLA-A/IFNA10/TSC1/RAF1/HLA-C/CDKN1A	26
KEGG	hsa04380	Osteoclast differentiation	16/727	128/8135	0.1058	0.3865	0.3295	NFKBIA/IKBKB/JUND/TRAF6/SOCS3/PIK3R1/MAP3K7/PIK3CA/MAP3K14/ACP5/MAPK11/NFKB2/JUNB/LILRB3/CTSK/TGFBR2	16
KEGG	hsa05223	Non-small cell lung cancer	10/727	72/8135	0.106	0.3865	0.3295	CDK4/CASP9/PIK3R1/PIK3CA/RXRB/GADD45A/SOS1/JAK3/RAF1/CDKN1A	10
KEGG	hsa05216	Thyroid cancer	6/727	37/8135	0.1077	0.3884	0.3311	TCF7L2/MYC/RXRB/GADD45A/CCDC6/CDKN1A	6
KEGG	hsa05226	Gastric cancer	18/727	149/8135	0.1152	0.4109	0.3503	FZD6/FRAT1/PIK3R1/PIK3CA/TCF7L2/MYC/RXRB/CDKN2B/CDKN1B/GADD45A/SOS1/ABCB1/RPS6KB2/FGF9/WNT10B/RAF1/CDKN1A/TGFBR2	18
KEGG	hsa04923	Regulation of lipolysis in adipocytes	8/727	56/8135	0.1232	0.4305	0.367	PNPLA2/PIK3R1/PIK3CA/PTGS1/ADRB1/TSHR/IRS2/LIPE	8
KEGG	hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	3/727	14/8135	0.1234	0.4305	0.367	ST3GAL3/ST3GAL2/B4GALT4	3
KEGG	hsa04015	Rap1 signaling pathway	24/727	210/8135	0.1247	0.4305	0.3671	RAC2/ACTG1/RGS14/LAT/THBS1/PIK3R1/PIK3CA/PLCB1/VAV1/ACTB/MAPK11/FLT4/VASP/CALML4/PARD6G/RAPGEF2/LPAR3/CTNND1/LPAR2/FGF9/ADORA2A/RAF1/PRKCI/PDGFC	24
KEGG	hsa05214	Glioma	10/727	75/8135	0.1296	0.4396	0.3748	CDK4/CAMK2D/PIK3R1/PIK3CA/CALML4/GADD45A/SOS1/CAMK1D/RAF1/CDKN1A	10
KEGG	hsa04936	Alcoholic liver disease	17/727	142/8135	0.1306	0.4396	0.3748	CPT1B/NFKBIA/IKBKB/CPT1C/TRAF6/PRKAB1/ADIPOR2/MAP3K7/PRKAG2/MAP3K14/TCF7L2/MAPK11/FADD/IL12A/IFNA10/C5/SIRT1	17
KEGG	hsa04350	TGF-beta signaling pathway	12/727	94/8135	0.1315	0.4396	0.3748	CREBBP/THBS1/MYC/CDKN2B/ACVR1B/BMP4/TGIF2/SMURF1/RPS6KB2/EP300/GREM2/TGFBR2	12
KEGG	hsa04012	ErbB signaling pathway	11/727	85/8135	0.1349	0.4422	0.377	HBEGF/CAMK2D/PIK3R1/PIK3CA/MYC/CDKN1B/SOS1/RPS6KB2/CBLB/RAF1/CDKN1A	11
KEGG	hsa04620	Toll-like receptor signaling pathway	13/727	104/8135	0.135	0.4422	0.377	IRF7/NFKBIA/IKBKB/TLR5/TRAF6/PIK3R1/MAP3K7/PIK3CA/MAPK11/FADD/IL12A/CTSK/IFNA10	13
KEGG	hsa00260	Glycine, serine and threonine metabolism	6/727	40/8135	0.1426	0.4592	0.3915	PSAT1/PGAM4/PSPH/GCAT/CTH/DLD	6
KEGG	hsa03430	Mismatch repair	4/727	23/8135	0.1442	0.4592	0.3915	POLD2/POLD4/RPA2/RPA1	4
KEGG	hsa00604	Glycosphingolipid biosynthesis - ganglio series	3/727	15/8135	0.1445	0.4592	0.3915	ST6GALNAC4/ST3GAL5/ST3GAL2	3
KEGG	hsa05205	Proteoglycans in cancer	23/727	205/8135	0.1501	0.4679	0.3989	PTPN6/HBEGF/ACTG1/FZD6/CAMK2D/THBS1/PIK3R1/PIK3CA/NUDT16L1/MYC/VAV1/ACTB/MAPK11/FRS2/TWIST1/VTN/SOS1/RPS6KB2/WNT10B/COL1A1/RAF1/CDKN1A/RRAS2	23
KEGG	hsa04215	Apoptosis - multiple species	5/727	32/8135	0.1525	0.4679	0.3989	CASP9/FADD/BID/BCL2L1/CASP7	5
KEGG	hsa04330	Notch signaling pathway	8/727	59/8135	0.153	0.4679	0.3989	NOTCH1/ATXN1L/CREBBP/CIR1/DTX3L/HDAC2/EP300/MFNG	8
KEGG	hsa04370	VEGF signaling pathway	8/727	59/8135	0.153	0.4679	0.3989	RAC2/MAPKAPK3/CASP9/PIK3R1/PIK3CA/MAPK11/NOS3/RAF1	8
KEGG	hsa05219	Bladder cancer	6/727	41/8135	0.1552	0.47	0.4007	CDK4/HBEGF/THBS1/MYC/RAF1/CDKN1A	6
KEGG	hsa05224	Breast cancer	17/727	147/8135	0.1624	0.4837	0.4124	CDK4/NOTCH1/FZD6/FRAT1/PIK3R1/PIK3CA/TCF7L2/MYC/NFKB2/FLT4/GADD45A/SOS1/RPS6KB2/FGF9/WNT10B/RAF1/CDKN1A	17
KEGG	hsa04310	Wnt signaling pathway	19/727	167/8135	0.1628	0.4837	0.4124	RAC2/ROR2/FZD6/CAMK2D/CBY1/FRAT1/CCND3/CREBBP/MAP3K7/PLCB1/TCF7L2/MYC/CSNK1E/SENP2/EP300/DKK4/WNT10B/DKK2/PRICKLE3	19
KEGG	hsa03013	Nucleocytoplasmic transport	13/727	108/8135	0.1653	0.4869	0.4152	NUP50/IPO13/KPNA5/DDX19B/NUP133/AAAS/NUP35/SENP2/XPO4/SRRM1/SUMO4/CSE1L/UPF1	13
KEGG	hsa05010	Alzheimer disease	40/727	384/8135	0.1704	0.4972	0.4239	SLC39A14/NDUFS7/CDK5/NRBF2/IKBKB/NDUFS2/FZD6/FRAT1/NDUFA12/TUBB6/CASP9/SLC25A6/PIK3R1/PIK3CA/SLC39A1/PLCB1/ATP2A1/NDUFB8/CSNK1E/FADD/SLC25A4/BID/ATG14/PSMA5/CALML4/ATG2A/NDUFB11/PSMA2/NDUFB2/ATF4/DKK4/WNT10B/IRS2/DKK2/NDUFB10/PSMB3/RAF1/CASP7/PSMD2/SLC11A2	40
KEGG	hsa04530	Tight junction	19/727	169/8135	0.1756	0.5045	0.4302	CDK4/CLDN15/MYH10/ACTG1/PRKAB1/WHAMM/ARPC1B/PRKAG2/MPP5/MYL6B/ACTB/VASP/RAB13/PARD6G/PRKCE/RAPGEF2/MYL12A/PRKCI/ARPC5	19
KEGG	hsa05418	Fluid shear stress and atherosclerosis	16/727	139/8135	0.176	0.5045	0.4302	RAC2/IKBKB/ACTG1/NFE2L2/DUSP1/PIK3R1/MAP3K7/PIK3CA/GSTM4/ACTB/MAPK11/BMP4/NOS3/CALML4/SUMO4/ASS1	16
KEGG	hsa00450	Selenocompound metabolism	3/727	17/8135	0.1898	0.5344	0.4556	SEPSECS/INMT/CTH	3
KEGG	hsa00910	Nitrogen metabolism	3/727	17/8135	0.1898	0.5344	0.4556	CA8/CA5B/CA4	3
KEGG	hsa05017	Spinocerebellar ataxia	16/727	143/8135	0.2064	0.568	0.4843	NRBF2/ATXN1L/SLC25A6/PIK3R1/PIK3CA/PLCB1/RORA/ATP2A1/SLC25A4/TBPL1/ATG14/PSMA5/ATG2A/PSMA2/PSMB3/PSMD2	16
KEGG	hsa04912	GnRH signaling pathway	11/727	93/8135	0.2064	0.568	0.4843	HBEGF/CAMK2D/MAP3K3/PLCB1/MAPK11/MMP14/CALML4/SOS1/ATF4/GNRH1/RAF1	11
KEGG	hsa04621	NOD-like receptor signaling pathway	20/727	184/8135	0.2084	0.568	0.4843	IRF7/GBP1/NFKBIA/IKBKB/PYCARD/TRAF6/TNFAIP3/OAS2/MAP3K7/TRPV2/ATG16L1/PLCB1/MAPK11/FADD/PKN2/BCL2L1/RBCK1/CARD6/IFNA10/OAS1	20
KEGG	hsa00061	Fatty acid biosynthesis	3/727	18/8135	0.2136	0.568	0.4843	CBR4/ACSL3/MCAT	3
KEGG	hsa00760	Nicotinate and nicotinamide metabolism	5/727	36/8135	0.2152	0.568	0.4843	ASPDH/PNP/NT5C1A/SIRT5/SIRT1	5
KEGG	hsa04657	IL-17 signaling pathway	11/727	94/8135	0.2163	0.568	0.4843	NFKBIA/IKBKB/JUND/TRAF6/TNFAIP3/MAP3K7/MAPK11/FADD/ELAVL1/TRAF4/MAPK6	11
KEGG	hsa04670	Leukocyte transendothelial migration	13/727	114/8135	0.2167	0.568	0.4843	RAC2/CLDN15/ACTG1/CXCR4/PIK3R1/PIK3CA/VAV1/ACTB/MAPK11/VASP/CTNND1/CD99/MYL12A	13
KEGG	hsa04064	NF-kappa B signaling pathway	12/727	104/8135	0.2168	0.568	0.4843	NFKBIA/IKBKB/LAT/TRAF6/TNFAIP3/MAP3K7/MAP3K14/BCL10/NFKB2/BCL2L1/GADD45A/DDX58	12
KEGG	hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	4/727	27/8135	0.2177	0.568	0.4843	ABO/ST3GAL3/FUT4/B4GALT4	4
KEGG	hsa03050	Proteasome	6/727	46/8135	0.225	0.5825	0.4966	PSME2/PSMA5/PSMA2/PSME4/PSMB3/PSMD2	6
KEGG	hsa05133	Pertussis	9/727	76/8135	0.236	0.6061	0.5168	CFL2/PYCARD/TRAF6/MAPK11/IL12A/CALML4/CFL1/C5/CASP7	9
KEGG	hsa00514	Other types of O-glycan biosynthesis	6/727	47/8135	0.2401	0.6068	0.5174	ST6GAL1/ST3GAL3/POGLUT1/POFUT2/MFNG/GALNT2	6
KEGG	hsa04973	Carbohydrate digestion and absorption	6/727	47/8135	0.2401	0.6068	0.5174	HK1/PIK3R1/PIK3CA/PLCB1/ATP1B2/HK2	6
KEGG	hsa00010	Glycolysis / Gluconeogenesis	8/727	67/8135	0.2469	0.6144	0.5238	HK1/PGAM4/PDHA1/PGK2/HK2/PFKL/PFKP/DLD	8
KEGG	hsa04720	Long-term potentiation	8/727	67/8135	0.2469	0.6144	0.5238	CAMK2D/CREBBP/RPS6KA1/PLCB1/CALML4/EP300/ATF4/RAF1	8
KEGG	hsa05340	Primary immunodeficiency	5/727	38/8135	0.2492	0.6154	0.5247	RFXANK/TAP1/AIRE/AICDA/JAK3	5
KEGG	hsa05016	Huntington disease	31/727	306/8135	0.2548	0.6245	0.5324	POLR2J3/NDUFS7/NRBF2/NDUFS2/DCTN4/POLR2D/NDUFA12/TUBB6/CREBBP/CASP9/SLC25A6/PLCB1/POLR2H/NDUFB8/AP2S1/SLC25A4/HDAC2/TBPL1/ATG14/PSMA5/ATG2A/NDUFB11/PSMA2/NDUFB2/EP300/GPX1/NDUFB10/PSMB3/HTT/PSMD2/IFT57	31
KEGG	hsa04664	Fc epsilon RI signaling pathway	8/727	68/8135	0.2598	0.6272	0.5347	RAC2/LAT/PIK3R1/PIK3CA/VAV1/MAPK11/SOS1/RAF1	8
KEGG	hsa04612	Antigen processing and presentation	9/727	78/8135	0.2599	0.6272	0.5347	RFXANK/PSME2/HSPA1A/TAP1/IFI30/HSPA1L/HLA-A/KIR2DL1/HLA-C	9
KEGG	hsa04935	Growth hormone synthesis, secretion and action	13/727	119/8135	0.264	0.6323	0.5391	SOCS3/CREBBP/PIK3R1/PIK3CA/SOCS2/PLCB1/MAPK11/JUNB/SOS1/EP300/ATF4/IRS2/RAF1	13
KEGG	hsa05012	Parkinson disease	27/727	266/8135	0.2695	0.6409	0.5464	SLC39A14/NDUFS7/NDUFS2/CAMK2D/NDUFA12/TUBB6/NFE2L2/CASP9/DUSP1/SLC25A6/SLC39A1/NDUFB8/PARK7/SLC25A4/BCL2L1/PSMA5/CALML4/NDUFB11/PSMA2/NDUFB2/ATF4/NDUFB10/PSMB3/ADORA2A/DAXX/PSMD2/SLC11A2	27
KEGG	hsa00030	Pentose phosphate pathway	4/727	30/8135	0.278	0.6551	0.5585	TKTL1/TALDO1/PFKL/PFKP	4
KEGG	hsa04933	AGE-RAGE signaling pathway in diabetic complications	11/727	100/8135	0.2796	0.6551	0.5585	PIM1/CDK4/PIK3R1/PIK3CA/PLCB1/CDKN1B/MAPK11/NOS3/PRKCE/COL1A1/TGFBR2	11
KEGG	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	8/727	70/8135	0.2862	0.6584	0.5613	HBEGF/NFKBIA/IKBKB/CSK/MAP3K14/MAPK11/ATP6V1G1/ATP6V0E1	8
KEGG	hsa04151	PI3K-Akt signaling pathway	35/727	354/8135	0.287	0.6584	0.5613	CDK4/IKBKB/GNG4/COL6A2/CCND3/THBS1/CASP9/PIK3R1/PIK3CA/THBS3/MYC/ITGA10/CDKN1B/PKN2/FLT4/GNG8/NOS3/VTN/BCL2L1/SOS1/ITGA3/RPS6KB2/YWHAZ/LPAR3/ATF4/LPAR2/FGF9/JAK3/COL1A1/IFNA10/TSC1/RAF1/PHLPP1/CDKN1A/PDGFC	35
KEGG	hsa05416	Viral myocarditis	7/727	60/8135	0.2871	0.6584	0.5613	RAC2/ACTG1/CASP9/ACTB/BID/HLA-A/HLA-C	7
KEGG	hsa00270	Cysteine and methionine metabolism	6/727	51/8135	0.3029	0.6895	0.5879	PSAT1/MAT2B/AHCY/BCAT1/MAT2A/CTH	6
KEGG	hsa05022	Pathways of neurodegeneration - multiple diseases	46/727	476/8135	0.3066	0.6931	0.591	NDUFS7/CDK5/NRBF2/NDUFS2/DCTN4/FZD6/CAMK2D/ATXN1L/FRAT1/NDUFA12/TUBB6/CASP9/SLC25A6/PLCB1/ATP2A1/NDUFB8/PARK7/MAPK11/CSNK1E/FADD/SLC25A4/SMCR8/BID/BCL2L1/ATG14/PSMA5/CALML4/ATG2A/NDUFB11/PSMA2/NDUFB2/ATF4/SIGMAR1/DKK4/GPX1/WNT10B/VCP/DKK2/NDUFB10/PSMB3/RAF1/DAXX/HTT/CASP7/PSMD2/IFT57	46
KEGG	hsa05218	Melanoma	8/727	72/8135	0.3132	0.6939	0.5916	CDK4/PIK3R1/PIK3CA/GADD45A/FGF9/RAF1/CDKN1A/PDGFC	8
KEGG	hsa00220	Arginine biosynthesis	3/727	22/8135	0.3135	0.6939	0.5916	ACY1/NOS3/ASS1	3
KEGG	hsa00900	Terpenoid backbone biosynthesis	3/727	22/8135	0.3135	0.6939	0.5916	FDPS/PMVK/MVK	3
KEGG	hsa03450	Non-homologous end-joining	2/727	13/8135	0.3261	0.7089	0.6044	POLL/NHEJ1	2
KEGG	hsa01524	Platinum drug resistance	8/727	73/8135	0.3269	0.7089	0.6044	CASP9/PIK3R1/PIK3CA/GSTM4/FADD/BID/BCL2L1/CDKN1A	8
KEGG	hsa04390	Hippo signaling pathway	16/727	157/8135	0.3279	0.7089	0.6044	ACTG1/FZD6/CCND3/MPP5/TCF7L2/MYC/ACTB/CSNK1E/BMP4/CSNK1D/PARD6G/YWHAZ/WNT10B/LATS2/PRKCI/TGFBR2	16
KEGG	hsa01200	Carbon metabolism	12/727	115/8135	0.3303	0.7089	0.6044	PSAT1/HK1/PGAM4/PDHA1/TKTL1/TALDO1/PSPH/PGK2/HK2/PFKL/PFKP/DLD	12
KEGG	hsa04623	Cytosolic DNA-sensing pathway	7/727	63/8135	0.3313	0.7089	0.6044	IRF7/NFKBIA/IKBKB/PYCARD/POLR2H/IFNA10/DDX58	7
KEGG	hsa00515	Mannose type O-glycan biosynthesis	3/727	23/8135	0.3388	0.7181	0.6122	ST3GAL3/FUT4/FKRP	3
KEGG	hsa04510	Focal adhesion	20/727	201/8135	0.34	0.7181	0.6122	RAC2/ACTG1/COL6A2/CCND3/THBS1/PIK3R1/PIK3CA/THBS3/VAV1/ITGA10/ACTB/FLT4/VTN/VASP/SOS1/ITGA3/COL1A1/MYL12A/RAF1/PDGFC	20
KEGG	hsa04929	GnRH secretion	7/727	64/8135	0.3462	0.7243	0.6175	KCNN4/HCN2/PIK3R1/PIK3CA/PLCB1/GNRH1/RAF1	7
KEGG	hsa04928	Parathyroid hormone synthesis, secretion and action	11/727	106/8135	0.3476	0.7243	0.6175	HBEGF/NR4A2/JUND/MMP17/PLCB1/RXRB/MMP14/MEF2D/ATF4/RAF1/CDKN1A	11
KEGG	hsa04915	Estrogen signaling pathway	14/727	138/8135	0.3497	0.7243	0.6175	HBEGF/PIK3R1/PIK3CA/PLCB1/FKBP4/HSPA1A/NOS3/CALML4/SOS1/ATF4/HSPA1L/KRT17/RAF1/NCOA2	14
KEGG	hsa03020	RNA polymerase	4/727	34/8135	0.3616	0.7441	0.6344	POLR2J3/CD3EAP/POLR2D/POLR2H	4
KEGG	hsa04926	Relaxin signaling pathway	13/727	129/8135	0.3671	0.7505	0.6399	NFKBIA/GNG4/PIK3R1/PIK3CA/PLCB1/MAPK11/GNG8/NOS3/SOS1/ATF4/COL1A1/RAF1/TGFBR2	13
KEGG	hsa05100	Bacterial invasion of epithelial cells	8/727	77/8135	0.3825	0.7766	0.6622	ACTG1/ARPC1B/PIK3R1/PIK3CA/ACTB/DNM2/WASL/ARPC5	8
KEGG	hsa04340	Hedgehog signaling pathway	6/727	56/8135	0.3847	0.7766	0.6622	CSNK1E/CSNK1D/SMURF1/SPOPL/SPOP/GPR161	6
KEGG	hsa00603	Glycosphingolipid biosynthesis - globo and isoglobo series	2/727	15/8135	0.3931	0.7886	0.6723	NAGA/ST3GAL2	2
KEGG	hsa04142	Lysosome	13/727	132/8135	0.3993	0.7961	0.6787	HYAL3/NAGA/M6PR/CTSH/CTSA/ACP5/GBA/GALC/PLA2G15/GM2A/CTSK/CTNS/SLC11A2	13
KEGG	hsa00512	Mucin type O-glycan biosynthesis	4/727	36/8135	0.4035	0.7996	0.6817	ST6GALNAC4/ST3GAL2/GALNT2/ST6GALNAC1	4
KEGG	hsa00240	Pyrimidine metabolism	6/727	58/8135	0.4176	0.8156	0.6954	DTYMK/DCTPP1/DHODH/CAD/NT5C1A/ENTPD5	6
KEGG	hsa05145	Toxoplasmosis	11/727	112/8135	0.418	0.8156	0.6954	NFKBIA/IKBKB/TRAF6/CASP9/MAP3K7/MAPK11/HSPA1A/BCL2L1/IL12A/IRGM/HSPA1L	11
KEGG	hsa00250	Alanine, aspartate and glutamate metabolism	4/727	37/8135	0.4243	0.8156	0.6954	GFPT2/ALDH4A1/CAD/ASS1	4
KEGG	hsa04960	Aldosterone-regulated sodium reabsorption	4/727	37/8135	0.4243	0.8156	0.6954	PIK3R1/PIK3CA/NR3C2/ATP1B2	4
KEGG	hsa05143	African trypanosomiasis	4/727	37/8135	0.4243	0.8156	0.6954	APOL1/PLCB1/IL12A/APOA1	4
KEGG	hsa05142	Chagas disease	10/727	102/8135	0.4285	0.8186	0.698	NFKBIA/IKBKB/TRAF6/PIK3R1/PIK3CA/PLCB1/MAPK11/FADD/IL12A/TGFBR2	10
KEGG	hsa05208	Chemical carcinogenesis - reactive oxygen species	21/727	223/8135	0.434	0.8243	0.7028	NDUFS7/NFKBIA/IKBKB/NDUFS2/NDUFA12/NFE2L2/SLC25A6/PIK3R1/PIK3CA/MAP3K14/GSTM4/NDUFB8/MAPK11/SLC25A4/SOS1/NDUFB11/NDUFB2/AKR1C2/NDUFB10/SLC26A2/RAF1	21
KEGG	hsa00513	Various types of N-glycan biosynthesis	4/727	39/8135	0.4653	0.8702	0.7419	ALG2/ST3GAL3/ALG3/B4GALNT3	4
KEGG	hsa00510	N-Glycan biosynthesis	5/727	50/8135	0.4663	0.8702	0.7419	ST6GAL1/ALG2/ALG3/MGAT3/DPM1	5
KEGG	hsa05110	Vibrio cholerae infection	5/727	50/8135	0.4663	0.8702	0.7419	ACTG1/ACTB/ATP6V1G1/ATP6V0E1/SEC61A2	5
KEGG	hsa04371	Apelin signaling pathway	13/727	139/8135	0.4747	0.8788	0.7493	GNG4/PRKAB1/PRKAG2/PLCB1/GNG8/NOS3/CALML4/MEF2D/PRKCE/RPS6KB2/LIPE/RAF1/RRAS2	13
KEGG	hsa05020	Prion disease	25/727	273/8135	0.4801	0.8788	0.7493	NDUFS7/RAC2/NOTCH1/STIP1/NDUFS2/NDUFA12/TUBB6/CASP9/SLC25A6/PIK3R1/PIK3CA/NDUFB8/MAPK11/SLC25A4/HSPA1A/PSMA5/NDUFB11/PSMA2/NDUFB2/ATF4/NDUFB10/HSPA1L/PSMB3/C5/PSMD2	25
KEGG	hsa04392	Hippo signaling pathway - multiple species	3/727	29/8135	0.4867	0.8788	0.7493	RASSF2/CSNK1E/LATS2	3
KEGG	hsa04744	Phototransduction	3/727	29/8135	0.4867	0.8788	0.7493	PDE6G/CALML4/RCVRN	3
KEGG	hsa00511	Other glycan degradation	2/727	18/8135	0.4872	0.8788	0.7493	MAN2C1/GBA	2
KEGG	hsa05014	Amyotrophic lateral sclerosis	33/727	364/8135	0.4928	0.8788	0.7493	HNRNPA1L2/NUP50/NDUFS7/NRBF2/ACTG1/NDUFS2/DCTN4/NDUFA12/TUBB6/CASP9/NUP133/NDUFB8/ACTB/MAPK11/SMCR8/BID/NUP35/BCL2L1/ATG14/PSMA5/ATG2A/NDUFB11/PSMA2/NDUFB2/ATF4/SIGMAR1/GPX1/VCP/NDUFB10/HNRNPA1/PSMB3/DAXX/PSMD2	33
KEGG	hsa04145	Phagosome	14/727	152/8135	0.4944	0.8788	0.7493	ACTG1/TUBB6/THBS1/THBS3/M6PR/ACTB/TAP1/ATP6V1G1/CORO1A/DYNC1LI2/ATP6V0E1/HLA-A/HLA-C/SEC61A2	14
KEGG	hsa05217	Basal cell carcinoma	6/727	63/8135	0.4986	0.8788	0.7493	FZD6/TCF7L2/BMP4/GADD45A/WNT10B/CDKN1A	6
KEGG	hsa00600	Sphingolipid metabolism	5/727	52/8135	0.5016	0.8788	0.7493	KDSR/GBA/GALC/SMPD4/SPTLC2	5
KEGG	hsa04659	Th17 cell differentiation	10/727	108/8135	0.5022	0.8788	0.7493	NFKBIE/NFKBIA/IKBKB/LAT/RORA/RXRB/MAPK11/IL27RA/JAK3/TGFBR2	10
KEGG	hsa04216	Ferroptosis	4/727	41/8135	0.5052	0.8788	0.7493	SLC39A14/LPCAT3/ACSL3/SLC11A2	4
KEGG	hsa01523	Antifolate resistance	3/727	30/8135	0.5098	0.8788	0.7493	GART/IKBKB/DHFR	3
KEGG	hsa03320	PPAR signaling pathway	7/727	75/8135	0.5106	0.8788	0.7493	CPT1B/CPT1C/RXRB/SLC27A4/ACSL3/GK/APOA1	7
KEGG	hsa04024	cAMP signaling pathway	20/727	221/8135	0.5114	0.8788	0.7493	RAC2/NFKBIA/CAMK2D/CREBBP/HCN2/PIK3R1/PIK3CA/ATP2A1/VAV1/HTR6/ATP1B2/CALML4/HCAR1/EP300/ADRB1/TSHR/ADORA2A/LIPE/RAF1/RRAS2	20
KEGG	hsa01210	2-Oxocarboxylic acid metabolism	2/727	19/8135	0.5165	0.8788	0.7493	BCAT1/ACY1	2
KEGG	hsa04925	Aldosterone synthesis and secretion	9/727	98/8135	0.5174	0.8788	0.7493	NR4A2/CAMK2D/PLCB1/ATP1B2/CALML4/PRKCE/ATF4/CAMK1D/LIPE	9
KEGG	hsa05231	Choline metabolism in cancer	9/727	98/8135	0.5174	0.8788	0.7493	RAC2/CHKB/PIK3R1/PIK3CA/SOS1/RPS6KB2/TSC1/RAF1/PDGFC	9
KEGG	hsa04971	Gastric acid secretion	7/727	76/8135	0.5251	0.8871	0.7563	ACTG1/CAMK2D/PLCB1/ACTB/ATP1B2/CALML4/KCNE2	7
KEGG	hsa04022	cGMP-PKG signaling pathway	15/727	167/8135	0.532	0.8941	0.7623	SRF/SLC25A6/PLCB1/ATP2A1/SLC25A4/NOS3/ATP1B2/VASP/CALML4/MEF2D/PRKCE/ATF4/ADRB1/IRS2/RAF1	15
KEGG	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	7/727	77/8135	0.5393	0.9017	0.7688	ACTG1/CACNA2D4/TCF7L2/ATP2A1/ITGA10/ACTB/ITGA3	7
KEGG	hsa00100	Steroid biosynthesis	2/727	20/8135	0.5447	0.9059	0.7724	CYP51A1/DHCR7	2
KEGG	hsa05152	Tuberculosis	16/727	180/8135	0.548	0.9067	0.7731	CAMK2D/TRAF6/CREBBP/RFXANK/CASP9/CASP10/BCL10/MAPK11/FADD/BID/IL12A/CALML4/EP300/CORO1A/IFNA10/RAF1	16
KEGG	hsa04062	Chemokine signaling pathway	17/727	192/8135	0.5539	0.9088	0.7749	RAC2/NFKBIA/IKBKB/GNG4/CXCL13/CXCR4/PIK3R1/PIK3CA/PLCB1/GSK3A/VAV1/GNG8/SOS1/JAK3/CXCL16/GRK6/RAF1	17
KEGG	hsa04916	Melanogenesis	9/727	101/8135	0.5549	0.9088	0.7749	FZD6/CAMK2D/CREBBP/PLCB1/TCF7L2/CALML4/EP300/WNT10B/RAF1	9
KEGG	hsa05410	Hypertrophic cardiomyopathy	8/727	90/8135	0.5606	0.9135	0.7788	ACTG1/PRKAB1/PRKAG2/CACNA2D4/ATP2A1/ITGA10/ACTB/ITGA3	8
KEGG	hsa01521	EGFR tyrosine kinase inhibitor resistance	7/727	79/8135	0.5673	0.9178	0.7825	PIK3R1/PIK3CA/BCL2L1/SOS1/RPS6KB2/RAF1/PDGFC	7
KEGG	hsa04723	Retrograde endocannabinoid signaling	13/727	148/8135	0.569	0.9178	0.7825	NDUFS7/GNG4/NDUFS2/NDUFA12/PLCB1/NDUFB8/MAPK11/GNG8/NAPEPLD/NDUFB11/NDUFB2/NDUFB10/ABHD6	13
KEGG	hsa04130	SNARE interactions in vesicular transport	3/727	33/8135	0.5759	0.9243	0.788	SNAP23/GOSR1/VAMP1	3
KEGG	hsa01212	Fatty acid metabolism	5/727	57/8135	0.5853	0.9316	0.7943	CPT1B/CPT1C/CBR4/ACSL3/MCAT	5
KEGG	hsa04658	Th1 and Th2 cell differentiation	8/727	92/8135	0.5863	0.9316	0.7943	NFKBIE/NOTCH1/NFKBIA/IKBKB/LAT/MAPK11/IL12A/JAK3	8
KEGG	hsa00040	Pentose and glucuronate interconversions	3/727	34/8135	0.5966	0.9402	0.8016	XYLB/UGDH/SORD	3
KEGG	hsa00340	Histidine metabolism	2/727	22/8135	0.5975	0.9402	0.8016	AMDHD1/CNDP1	2
KEGG	hsa04964	Proximal tubule bicarbonate reclamation	2/727	23/8135	0.6222	0.9742	0.8306	ATP1B2/CA4	2
KEGG	hsa04921	Oxytocin signaling pathway	13/727	154/8135	0.6279	0.9752	0.8314	ACTG1/CAMK2D/PRKAB1/PRKAG2/CACNA2D4/PLCB1/MYL6B/ACTB/NOS3/CALML4/CAMK1D/RAF1/CDKN1A	13
KEGG	hsa04071	Sphingolipid signaling pathway	10/727	119/8135	0.6288	0.9752	0.8314	RAC2/PIK3R1/PIK3CA/PLCB1/MAPK11/BID/NOS3/PRKCE/RAF1/SPTLC2	10
KEGG	hsa04550	Signaling pathways regulating pluripotency of stem cells	12/727	143/8135	0.6345	0.9769	0.8329	FZD6/PIK3R1/PIK3CA/MYC/ACVR1B/MAPK11/BMP4/KLF4/JARID2/WNT10B/JAK3/RAF1	12
KEGG	hsa00500	Starch and sucrose metabolism	3/727	36/8135	0.6361	0.9769	0.8329	HK1/GBE1/HK2	3
KEGG	hsa04977	Vitamin digestion and absorption	2/727	24/8135	0.6456	0.9817	0.837	MMACHC/APOA1	2
KEGG	hsa01232	Nucleotide metabolism	7/727	85/8135	0.6461	0.9817	0.837	AMPD2/DTYMK/DCTPP1/PNP/NT5C1A/ENTPD5/AK3	7
KEGG	hsa03008	Ribosome biogenesis in eukaryotes	9/727	109/8135	0.6484	0.9817	0.837	NOP10/POP1/WDR75/TBL3/UTP15/REXO1/RPP40/SBDS/REXO2	9
KEGG	hsa04750	Inflammatory mediator regulation of TRP channels	8/727	98/8135	0.6585	0.9924	0.8461	CAMK2D/PIK3R1/PIK3CA/TRPV2/PLCB1/MAPK11/CALML4/PRKCE	8
KEGG	hsa05202	Transcriptional misregulation in cancer	16/727	193/8135	0.6624	0.9936	0.8471	CCNT1/MEN1/REL/MYC/RXRB/KLF3/CDKN1B/HDAC2/BCL2L1/FLI1/CEBPA/GADD45A/TAF15/BCL6/CDKN1A/TGFBR2	16
KEGG	hsa05330	Allograft rejection	3/727	38/8135	0.6727	0.9953	0.8486	IL12A/HLA-A/HLA-C	3
KEGG	hsa04217	Necroptosis	13/727	159/8135	0.6739	0.9953	0.8486	SPATA2/TNFRSF10B/CAMK2D/PYCARD/TNFAIP3/SLC25A6/TNFSF10/FADD/SLC25A4/BID/RBCK1/JAK3/IFNA10	13
KEGG	hsa00330	Arginine and proline metabolism	4/727	51/8135	0.6802	0.9953	0.8486	CNDP1/NOS3/ALDH4A1/ALDH18A1	4
KEGG	hsa04072	Phospholipase D signaling pathway	12/727	148/8135	0.6817	0.9953	0.8486	PIK3R1/PIK3CA/PLCB1/DNM2/SOS1/LPAR3/LPAR2/TSC1/RAF1/CYTH3/PDGFC/RRAS2	12
KEGG	hsa04512	ECM-receptor interaction	7/727	88/8135	0.6821	0.9953	0.8486	COL6A2/THBS1/THBS3/ITGA10/VTN/ITGA3/COL1A1	7
KEGG	hsa04540	Gap junction	7/727	88/8135	0.6821	0.9953	0.8486	TUBB6/PLCB1/CSNK1D/SOS1/ADRB1/RAF1/PDGFC	7
KEGG	hsa00790	Folate biosynthesis	2/727	26/8135	0.689	1	0.8526	GCH1/DHFR	2
KEGG	hsa05140	Leishmaniasis	6/727	77/8135	0.6967	1	0.8526	PTPN6/NFKBIA/TRAF6/MAP3K7/MAPK11/IL12A	6
KEGG	hsa04914	Progesterone-mediated oocyte maturation	8/727	102/8135	0.7023	1	0.8526	KIF22/RPS6KA1/PIK3R1/PIK3CA/MAPK11/ANAPC7/CDC25B/RAF1	8
KEGG	hsa04966	Collecting duct acid secretion	2/727	27/8135	0.7091	1	0.8526	ATP6V1G1/ATP6V0E1	2
KEGG	hsa04961	Endocrine and other factor-regulated calcium reabsorption	4/727	53/8135	0.7095	1	0.8526	PLCB1/AP2S1/DNM2/ATP1B2	4
KEGG	hsa05320	Autoimmune thyroid disease	4/727	53/8135	0.7095	1	0.8526	TSHR/HLA-A/IFNA10/HLA-C	4
KEGG	hsa04974	Protein digestion and absorption	8/727	103/8135	0.7127	1	0.8526	CTRL/COL6A2/KCNN4/SLC1A5/SLC3A1/ATP1B2/SLC7A9/COL1A1	8
KEGG	hsa05207	Chemical carcinogenesis - receptor activation	17/727	212/8135	0.7176	1	0.8526	CCND3/KPNA5/RPS6KA1/PIK3R1/PIK3CA/GSTM4/MYC/RXRB/KLF4/SOS1/RPS6KB2/PAQR7/ATF4/FGF9/ADRB1/RAF1/BCL6	17
KEGG	hsa00650	Butanoate metabolism	2/727	28/8135	0.728	1	0.8526	HMGCL/BDH1	2
KEGG	hsa04613	Neutrophil extracellular trap formation	15/727	190/8135	0.7316	1	0.8526	RAC2/ACTG1/SLC25A6/PIK3R1/MAP3K7/AZU1/PIK3CA/PLCB1/ACTB/MAPK11/SLC25A4/HDAC2/RAF1/SELPLG/C5	15
KEGG	hsa04120	Ubiquitin mediated proteolysis	11/727	142/8135	0.7346	1	0.8526	TRAF6/SOCS3/ANAPC7/SMURF1/UBA3/DDB1/AIRE/CBLB/HERC3/SKP2/UBE3A	11
KEGG	hsa00380	Tryptophan metabolism	3/727	42/8135	0.7377	1	0.8526	ALDH8A1/INMT/DLD	3
KEGG	hsa05332	Graft-versus-host disease	3/727	42/8135	0.7377	1	0.8526	HLA-A/KIR2DL1/HLA-C	3
KEGG	hsa04934	Cushing syndrome	12/727	155/8135	0.7413	1	0.8526	CDK4/FZD6/CAMK2D/MEN1/NCEH1/PLCB1/TCF7L2/CDKN2B/CDKN1B/ATF4/WNT10B/CDKN1A	12
KEGG	hsa05031	Amphetamine addiction	5/727	69/8135	0.7505	1	0.8526	CAMK2D/HDAC2/CALML4/ATF4/SIRT1	5
KEGG	hsa00071	Fatty acid degradation	3/727	43/8135	0.7523	1	0.8526	CPT1B/CPT1C/ACSL3	3
KEGG	hsa04940	Type I diabetes mellitus	3/727	43/8135	0.7523	1	0.8526	IL12A/HLA-A/HLA-C	3
KEGG	hsa04360	Axon guidance	14/727	182/8135	0.7612	1	0.8526	RAC2/CDK5/SEMA4C/CAMK2D/CFL2/CXCR4/PIK3R1/PIK3CA/SEMA4F/PARD6G/CFL1/PLXNA4/MYL12A/RAF1	14
KEGG	hsa00020	Citrate cycle (TCA cycle)	2/727	30/8135	0.7627	1	0.8526	PDHA1/DLD	2
KEGG	hsa04962	Vasopressin-regulated water reabsorption	3/727	44/8135	0.7662	1	0.8526	DCTN4/DYNC1LI2/DYNLL1	3
KEGG	hsa05414	Dilated cardiomyopathy	7/727	96/8135	0.7663	1	0.8526	ACTG1/CACNA2D4/ATP2A1/ITGA10/ACTB/ITGA3/ADRB1	7
KEGG	hsa04070	Phosphatidylinositol signaling system	7/727	97/8135	0.7756	1	0.8526	PIK3R1/PIK3CA/PLCB1/IP6K1/MTMR14/IMPAD1/CALML4	7
KEGG	hsa04713	Circadian entrainment	7/727	97/8135	0.7756	1	0.8526	PER1/GNG4/CAMK2D/PLCB1/GNG8/CALML4/PER3	7
KEGG	hsa00430	Taurine and hypotaurine metabolism	1/727	16/8135	0.7767	1	0.8526	ADO	1
KEGG	hsa02010	ABC transporters	3/727	45/8135	0.7794	1	0.8526	TAP1/ABCB1/ABCA5	3
KEGG	hsa04137	Mitophagy - animal	5/727	72/8135	0.7831	1	0.8526	BNIP3/BCL2L1/ATF4/RHOT2/RRAS2	5
KEGG	hsa00564	Glycerophospholipid metabolism	7/727	98/8135	0.7846	1	0.8526	ETNK1/CHKB/PNPLA7/MBOAT7/PLA2G15/LPCAT3/GPAM	7
KEGG	hsa04911	Insulin secretion	6/727	86/8135	0.7925	1	0.8526	CAMK2D/KCNN4/PLCB1/ATP1B2/SLC2A1/ATF4	6
KEGG	hsa04136	Autophagy - other	2/727	32/8135	0.7936	1	0.8526	ATG16L1/ATG2A	2
KEGG	hsa04978	Mineral absorption	4/727	60/8135	0.7964	1	0.8526	HMOX2/SLC30A1/ATP1B2/SLC11A2	4
KEGG	hsa04725	Cholinergic synapse	8/727	113/8135	0.803	1	0.8526	GNG4/CAMK2D/PIK3R1/PIK3CA/PLCB1/GNG8/CHRM4/ATF4	8
KEGG	hsa00620	Pyruvate metabolism	3/727	47/8135	0.8041	1	0.8526	PDHA1/ACYP2/DLD	3
KEGG	hsa04918	Thyroid hormone synthesis	5/727	75/8135	0.8123	1	0.8526	PLCB1/ATP1B2/ATF4/GPX1/TSHR	5
KEGG	hsa00280	Valine, leucine and isoleucine degradation	3/727	48/8135	0.8155	1	0.8526	HMGCL/BCAT1/DLD	3
KEGG	hsa04726	Serotonergic synapse	8/727	115/8135	0.8182	1	0.8526	GNG4/DUSP1/PLCB1/CYP2D6/GNG8/HTR6/PTGS1/RAF1	8
KEGG	hsa00230	Purine metabolism	9/727	128/8135	0.8193	1	0.8526	GART/AMPD2/PDE6G/NUDT9/PDE7A/PNP/NT5C1A/ENTPD5/AK3	9
KEGG	hsa04672	Intestinal immune network for IgA production	3/727	49/8135	0.8264	1	0.8526	CXCR4/MAP3K14/AICDA	3
KEGG	hsa00310	Lysine degradation	4/727	63/8135	0.8267	1	0.8526	EHMT2/ASH1L/SETD1B/DLD	4
KEGG	hsa00531	Glycosaminoglycan degradation	1/727	19/8135	0.8315	1	0.8526	HYAL3	1
KEGG	hsa05144	Malaria	3/727	50/8135	0.8367	1	0.8526	THBS1/THBS3/IL12A	3
KEGG	hsa04014	Ras signaling pathway	17/727	232/8135	0.8387	1	0.8526	RAC2/IKBKB/GNG4/RASA4/LAT/PIK3R1/PIK3CA/REL/FLT4/GNG8/BCL2L1/CALML4/SOS1/FGF9/RAF1/PDGFC/RRAS2	17
KEGG	hsa05171	Coronavirus disease - COVID-19	17/727	232/8135	0.8387	1	0.8526	HBEGF/RPL23A/NFKBIA/IKBKB/ISG15/TRAF6/PIK3R1/OAS2/MAP3K7/PIK3CA/MAPK11/RPL36AL/IL12A/IFNA10/DDX58/OAS1/C5	17
KEGG	hsa05321	Inflammatory bowel disease	4/727	65/8135	0.8447	1	0.8526	TLR5/RORA/IL18RAP/IL12A	4
KEGG	hsa00350	Tyrosine metabolism	2/727	36/8135	0.8447	1	0.8526	FAH/HGD	2
KEGG	hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	1/727	20/8135	0.8466	1	0.8526	CSGALNACT2	1
KEGG	hsa04141	Protein processing in endoplasmic reticulum	12/727	171/8135	0.8481	1	0.8526	NFE2L2/SAR1A/HSPA1A/DNAJB1/HERPUD1/ATF4/VCP/DNAJA1/HSPA1L/EIF2AK4/YOD1/SEC61A2	12
KEGG	hsa00190	Oxidative phosphorylation	9/727	134/8135	0.8576	1	0.8526	NDUFS7/NDUFS2/NDUFA12/NDUFB8/NDUFB11/NDUFB2/ATP6V1G1/ATP6V0E1/NDUFB10	9
KEGG	hsa00770	Pantothenate and CoA biosynthesis	1/727	21/8135	0.8603	1	0.8526	BCAT1	1
KEGG	hsa04020	Calcium signaling pathway	17/727	240/8135	0.8744	1	0.8526	CAMK2D/CXCR4/SLC25A6/PLCB1/ATP2A1/SLC25A4/FLT4/TNNC2/NOS3/HTR6/CALML4/MST1R/CAMK1D/FGF9/ADRB1/ADORA2A/PDGFC	17
KEGG	hsa03015	mRNA surveillance pathway	6/727	97/8135	0.876	1	0.8526	CLP1/DDX19B/SRRM1/WDR33/UPF1/MSI2	6
KEGG	hsa03060	Protein export	1/727	23/8135	0.8842	1	0.8526	SEC61A2	1
KEGG	hsa04614	Renin-angiotensin system	1/727	23/8135	0.8842	1	0.8526	CTSA	1
KEGG	hsa04061	Viral protein interaction with cytokine and cytokine receptor	6/727	100/8135	0.8931	1	0.8526	CXCL13/IL34/TNFRSF10B/CXCR4/TNFSF10/IL18RAP	6
KEGG	hsa00480	Glutathione metabolism	3/727	58/8135	0.9017	1	0.8526	GSTM4/CHAC2/GPX1	3
KEGG	hsa00562	Inositol phosphate metabolism	4/727	73/8135	0.9017	1	0.8526	PLCH2/PIK3CA/PLCB1/MTMR14	4
KEGG	hsa00860	Porphyrin metabolism	2/727	43/8135	0.9074	1	0.8526	HMOX2/ALAD	2
KEGG	hsa04975	Fat digestion and absorption	2/727	43/8135	0.9074	1	0.8526	SLC27A4/APOA1	2
KEGG	hsa04728	Dopaminergic synapse	8/727	132/8135	0.9134	1	0.8526	GNG4/CAMK2D/PLCB1/GSK3A/MAPK11/GNG8/CALML4/ATF4	8
KEGG	hsa00140	Steroid hormone biosynthesis	3/727	61/8135	0.9193	1	0.8526	SULT2B1/AKR1C2/HSD11B1	3
KEGG	hsa00561	Glycerolipid metabolism	3/727	61/8135	0.9193	1	0.8526	PNPLA2/GPAM/GK	3
KEGG	hsa04270	Vascular smooth muscle contraction	8/727	134/8135	0.9211	1	0.8526	MYH10/PTGIR/PLCB1/MYL6B/CALML4/PRKCE/ADORA2A/RAF1	8
KEGG	hsa00980	Metabolism of xenobiotics by cytochrome P450	4/727	78/8135	0.9271	1	0.8526	AKR7A3/GSTM4/CYP2D6/HSD11B1	4
KEGG	hsa04721	Synaptic vesicle cycle	4/727	78/8135	0.9271	1	0.8526	AP2S1/DNM2/ATP6V1G1/ATP6V0E1	4
KEGG	hsa04970	Salivary secretion	5/727	93/8135	0.9275	1	0.8526	KCNN4/PLCB1/ATP1B2/CALML4/ADRB1	5
KEGG	hsa04261	Adrenergic signaling in cardiomyocytes	9/727	150/8135	0.9288	1	0.8526	CAMK2D/CACNA2D4/PLCB1/ATP2A1/MAPK11/ATP1B2/CALML4/ATF4/ADRB1	9
KEGG	hsa05206	MicroRNAs in cancer	21/727	310/8135	0.9328	1	0.8526	PIM1/NOTCH1/IKBKB/CREBBP/THBS1/PIK3R1/PIK3CA/MYC/DICER1/CDKN1B/HDAC2/SOS1/PRKCE/ABCB1/EP300/IRS2/CDC25B/TP63/RAF1/CDKN1A/SIRT1	21
KEGG	hsa04927	Cortisol synthesis and secretion	3/727	65/8135	0.9383	1	0.8526	NCEH1/PLCB1/ATF4	3
KEGG	hsa00053	Ascorbate and aldarate metabolism	1/727	30/8135	0.94	1	0.8526	UGDH	1
KEGG	hsa00630	Glyoxylate and dicarboxylate metabolism	1/727	30/8135	0.94	1	0.8526	DLD	1
KEGG	hsa05030	Cocaine addiction	2/727	49/8135	0.9414	1	0.8526	CDK5/ATF4	2
KEGG	hsa00970	Aminoacyl-tRNA biosynthesis	3/727	66/8135	0.9424	1	0.8526	SEPSECS/DARS2/WARS2	3
KEGG	hsa00410	beta-Alanine metabolism	1/727	31/8135	0.9454	1	0.8526	CNDP1	1
KEGG	hsa04979	Cholesterol metabolism	2/727	50/8135	0.9457	1	0.8526	NCEH1/APOA1	2
KEGG	hsa00640	Propanoate metabolism	1/727	32/8135	0.9503	1	0.8526	DLD	1
KEGG	hsa04610	Complement and coagulation cascades	4/727	85/8135	0.9528	1	0.8526	VTN/F11/CD46/C5	4
KEGG	hsa04924	Renin secretion	3/727	69/8135	0.9531	1	0.8526	PLCB1/CALML4/ADRB1	3
KEGG	hsa05204	Chemical carcinogenesis - DNA adducts	3/727	69/8135	0.9531	1	0.8526	GSTM4/AKR1C2/HSD11B1	3
KEGG	hsa04972	Pancreatic secretion	5/727	102/8135	0.9569	1	0.8526	CTRL/PLCB1/ATP2A1/ATP1B2/RAB27B	5
KEGG	hsa05146	Amoebiasis	5/727	102/8135	0.9569	1	0.8526	PIK3R1/PIK3CA/PLCB1/IL12A/COL1A1	5
KEGG	hsa04976	Bile secretion	4/727	89/8135	0.9635	1	0.8526	NCEH1/ATP1B2/SLC2A1/ABCB1	4
KEGG	hsa05032	Morphine addiction	4/727	91/8135	0.9679	1	0.8526	GNG4/GNG8/PDE7A/GRK6	4
KEGG	hsa05323	Rheumatoid arthritis	4/727	93/8135	0.9718	1	0.8526	ACP5/ATP6V1G1/CTSK/ATP6V0E1	4
KEGG	hsa04730	Long-term depression	2/727	60/8135	0.9753	1	0.8526	PLCB1/RAF1	2
KEGG	hsa00590	Arachidonic acid metabolism	2/727	61/8135	0.9772	1	0.8526	PTGS1/GPX1	2
KEGG	hsa04114	Oocyte meiosis	6/727	131/8135	0.9807	1	0.8526	CAMK2D/RPS6KA1/MAPK11/ANAPC7/CALML4/YWHAZ	6
KEGG	hsa04514	Cell adhesion molecules	7/727	149/8135	0.9833	1	0.8526	CLDN15/NLGN3/HLA-A/CD99/MPZL1/HLA-C/SELPLG	7
KEGG	hsa04060	Cytokine-cytokine receptor interaction	17/727	295/8135	0.9844	1	0.8526	TNFRSF6B/CXCL13/IL34/TNFRSF10B/CXCR4/CD27/TNFSF10/ACVR1B/BMP4/CRLF2/IL18RAP/IL12A/CLCF1/IL27RA/CXCL16/IFNA10/TGFBR2	17
KEGG	hsa00830	Retinol metabolism	2/727	68/8135	0.9871	1	0.8526	DHRS3/DHRS4	2
KEGG	hsa04260	Cardiac muscle contraction	3/727	87/8135	0.9871	1	0.8526	CACNA2D4/ATP2A1/ATP1B2	3
KEGG	hsa05034	Alcoholism	9/727	187/8135	0.989	1	0.8526	GNG4/GNG8/SLC29A2/HDAC2/CALML4/SOS1/ATF4/ADORA2A/RAF1	9
KEGG	hsa03010	Ribosome	7/727	158/8135	0.9901	1	0.8526	MRPS5/MRPS18C/RPL23A/RPL36AL/MRPL15/MRPS21/MRPL24	7
KEGG	hsa00982	Drug metabolism - cytochrome P450	2/727	72/8135	0.9907	1	0.8526	GSTM4/CYP2D6	2
KEGG	hsa04724	Glutamatergic synapse	4/727	114/8135	0.9933	1	0.8526	GNG4/PLCB1/GNG8/HOMER2	4
KEGG	hsa05150	Staphylococcus aureus infection	3/727	96/8135	0.9934	1	0.8526	KRT17/SELPLG/C5	3
KEGG	hsa04727	GABAergic synapse	2/727	89/8135	0.9977	1	0.8526	GNG4/GNG8	2
KEGG	hsa04640	Hematopoietic cell lineage	2/727	99/8135	0.999	1	0.8526	ITGA3/CD7	2
KEGG	hsa00983	Drug metabolism - other enzymes	1/727	80/8135	0.9995	1	0.8526	GSTM4	1
KEGG	hsa04742	Taste transduction	1/727	86/8135	0.9997	1	0.8526	PLCB1	1
KEGG	hsa04080	Neuroactive ligand-receptor interaction	14/727	353/8135	0.9999	1	0.8526	PTGIR/PMCH/HTR6/THRA/CHRM4/LPAR3/LPAR2/ADRB1/GNRH1/TSHR/NMB/NR3C1/ADORA2A/C5	14
KEGG	hsa05322	Systemic lupus erythematosus	1/727	136/8135	1	1	0.8526	C5	1
KEGG	hsa04740	Olfactory transduction	10/727	440/8135	1	1	0.8526	OR2T3/CAMK2D/OR5V1/OR1B1/CALML4/OR9A2/OR4D1/OR52B2/OR2L8/OR8D4	10