ONTOLOGY	ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	qvalue	geneID	Count
BP	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	70/4749	120/18670	1.972e-14	1.263e-10	1.028e-10	HELZ2/RPL3/PPP2R1A/RPS8/RPL32/RPS25/RPS12/RPL10A/RPS18/RPS27/SMG5/RPL35/RPL38/RPS10/RPS3A/RPLP2/RPL21/RPL19/RPL23A/RPS5/RPL36/RPL5/RPL4/RPL30/RPL27A/RPL26/RPS23/RNPS1/RPS6/RPS15/RPL36A/RPL7/SMG9/RPL18A/RPS13/RPS20/RPL6/CTIF/RPS3/RPS15A/UPF1/RPS27A/MAGOHB/RPL23/RPS11/RPS19/UBA52/RPS16/PPP2CA/RPS9/RPL14/RPL37A/RPL37/RPL29/RPS4X/SMG8/RPL12/UPF3A/RPSA/MAGOH/RPS28/RPL7A/RPL39/SMG6/GSPT1/PNRC2/RPL11/EIF3E/NCBP2/RPL22	70
BP	GO:0019080	viral gene expression	92/4749	191/18670	9.143e-12	2.929e-08	2.382e-08	FURIN/SEC13/RPL3/RPS8/ZFP36/NUP98/RPL32/RPS25/RPS12/RPL10A/RPS18/RPS27/RPL35/RPL38/RPS10/RPS3A/SMARCB1/RPLP2/RPL21/RPL19/RPL23A/RPS5/RPL36/RPL5/RPL4/RPL30/RPL27A/PTBP1/RPL26/MON1B/RPS23/TRIM62/RPS6/RPS15/CCL3/RPL36A/RPL7/RPL18A/RPS13/RPS20/RPL6/USF2/NUP153/RPS3/RPS15A/RPS27A/RPL23/SMARCA4/RPS11/RPS19/CCNT2/UBA52/TRIM13/RPS16/RPS9/SP1/IFITM3/NUP88/RPL14/RPL37A/RPL37/POLR2I/MID2/JUN/TAF11/POM121C/RPL29/NUP205/EIF3L/RAE1/ZNF639/RPS4X/NUP50/POLR2C/RPL12/RPSA/EIF2D/RPS28/EIF3G/RPL7A/RPL39/POLR2J/DENR/NUP93/RPL11/NUP35/NUCKS1/AAAS/POLR2A/NUP62/SEH1L/RPL22	92
BP	GO:0019083	viral transcription	86/4749	177/18670	2.419e-11	5.166e-08	4.203e-08	SEC13/RPL3/RPS8/ZFP36/NUP98/RPL32/RPS25/RPS12/RPL10A/RPS18/RPS27/RPL35/RPL38/RPS10/RPS3A/SMARCB1/RPLP2/RPL21/RPL19/RPL23A/RPS5/RPL36/RPL5/RPL4/RPL30/RPL27A/RPL26/MON1B/RPS23/TRIM62/RPS6/RPS15/CCL3/RPL36A/RPL7/RPL18A/RPS13/RPS20/RPL6/USF2/NUP153/RPS3/RPS15A/RPS27A/RPL23/SMARCA4/RPS11/RPS19/CCNT2/UBA52/TRIM13/RPS16/RPS9/SP1/IFITM3/NUP88/RPL14/RPL37A/RPL37/POLR2I/MID2/JUN/TAF11/POM121C/RPL29/NUP205/RAE1/ZNF639/RPS4X/NUP50/POLR2C/RPL12/RPSA/RPS28/RPL7A/RPL39/POLR2J/NUP93/RPL11/NUP35/NUCKS1/AAAS/POLR2A/NUP62/SEH1L/RPL22	86
BP	GO:0006614	SRP-dependent cotranslational protein targeting to membrane	57/4749	105/18670	2.573e-10	4.072e-07	3.313e-07	RPL3/RPS8/RPL32/RPS25/RPS12/RPL10A/RPS18/RPS27/RPL35/RPL38/RPS10/RPS3A/RPLP2/RPL21/RPL19/RPL23A/RPS5/RPL36/RPL5/RPL4/RPL30/RPL27A/RPL26/RPS23/RPS6/RPS15/RPL36A/SEC61A2/RPL7/RPL18A/RPS13/RPS20/RPL6/RPS3/RPS15A/RPS27A/RPL23/RPS11/RPS19/UBA52/TRAM2/RPS16/RPS9/SEC61B/RPL14/RPL37A/RPL37/RPL29/RPS4X/RPL12/RPSA/RPS28/ZFAND2B/RPL7A/RPL39/RPL11/RPL22	57
BP	GO:0006401	RNA catabolic process	157/4749	397/18670	3.178e-10	4.072e-07	3.313e-07	HELZ2/TIRAP/RPL3/OAS2/PPP2R1A/YWHAZ/SERBP1/RPS8/ZFP36/E2F1/HSPA1A/ZC3H12D/RPL32/RPS25/RPS12/PLEKHN1/RPL10A/RPS18/RPS27/SMG5/MTOR/RPL35/RPL38/FEN1/RPS10/RPS3A/RPLP2/RPL21/RPL19/RPL23A/NUDT16/XRN2/RPS5/RPL36/RPL5/RPL4/RPL30/RPL27A/RPL26/PSMD8/RPS23/HNRNPA0/RNPS1/RPS6/RPS15/RPL36A/TNRC6B/PELO/UBB/RPL7/SMG9/PSMD1/PSMD2/RPL18A/RPS13/RPS20/RPL6/CTIF/RPS3/DCPS/RPS15A/PSMF1/CIRBP/UPF1/RPS27A/ISG20/ZFP36L2/MAGOHB/RPL23/RPS11/RPS19/PRKCA/DIS3L2/ALKBH5/RBM46/CNOT3/UBA52/RPS16/PPP2CA/MEX3D/PAN3/RPS9/PSMD9/PSMA5/RPL14/RPL37A/RNASEH2A/ZHX2/EDC4/RPL37/RBM23/FMR1/PSMB7/EXOSC2/RNH1/RPL29/PSMD5/RNASE6/SIDT2/RPS4X/SMG8/ZC3H12A/RPL12/VIM/UPF3A/PSME2/ELAVL1/CNOT7/RPSA/CSDC2/YTHDF3/FASTKD3/PPP1R8/MAGOH/METTL16/DNA2/TNFSF13/SAMD4B/GIGYF2/LRPPRC/RPS28/PSMB5/RBM38/ERN1/TNFRSF1B/MAPKAPK2/ZC3HAV1/RNASEH2C/RPL7A/MRTO4/RPL39/YBX1/SMG6/ZFP36L1/PSMB4/PSMA3/GSPT1/TBRG4/PNRC2/RPL11/AXIN2/EIF3E/ATM/NCBP2/PSMD10/TTC37/PSMB1/PSMD7/PSMB3/DIS3L/PSMC5/TNPO1/KHSRP/RPL22/EXOSC9/LSM2/PSMD11	157
BP	GO:0006613	cotranslational protein targeting to membrane	58/4749	109/18670	5.085e-10	5.429e-07	4.417e-07	RPL3/RPS8/RPL32/RPS25/RPS12/RPL10A/RPS18/RPS27/RPL35/RPL38/RPS10/RPS3A/RPLP2/RPL21/RPL19/RPL23A/RPS5/RPL36/RPL5/RPL4/RPL30/RPL27A/RPL26/RPS23/RPS6/RPS15/RPL36A/SEC61A2/RPL7/RPL18A/RPS13/RPS20/RPL6/RPS3/RPS15A/RPS27A/RPL23/RPS11/RPS19/UBA52/TRAM2/RPS16/RPS9/SEC61B/RPL14/RPL37A/RPL37/RPL29/RPS4X/RPL12/RPSA/RPS28/ZFAND2B/RPL7A/RPL39/RPL11/RPL22/SSR2	58
BP	GO:0006402	mRNA catabolic process	144/4749	364/18670	1.663e-09	1.522e-06	1.238e-06	HELZ2/TIRAP/RPL3/PPP2R1A/YWHAZ/SERBP1/RPS8/ZFP36/E2F1/HSPA1A/ZC3H12D/RPL32/RPS25/RPS12/PLEKHN1/RPL10A/RPS18/RPS27/SMG5/MTOR/RPL35/RPL38/RPS10/RPS3A/RPLP2/RPL21/RPL19/RPL23A/NUDT16/RPS5/RPL36/RPL5/RPL4/RPL30/RPL27A/RPL26/PSMD8/RPS23/HNRNPA0/RNPS1/RPS6/RPS15/RPL36A/TNRC6B/PELO/UBB/RPL7/SMG9/PSMD1/PSMD2/RPL18A/RPS13/RPS20/RPL6/CTIF/RPS3/DCPS/RPS15A/PSMF1/CIRBP/UPF1/RPS27A/ZFP36L2/MAGOHB/RPL23/RPS11/RPS19/PRKCA/DIS3L2/ALKBH5/RBM46/CNOT3/UBA52/RPS16/PPP2CA/MEX3D/PAN3/RPS9/PSMD9/PSMA5/RPL14/RPL37A/ZHX2/EDC4/RPL37/RBM23/FMR1/PSMB7/EXOSC2/RNH1/RPL29/PSMD5/RPS4X/SMG8/ZC3H12A/RPL12/VIM/UPF3A/PSME2/ELAVL1/CNOT7/RPSA/CSDC2/YTHDF3/FASTKD3/MAGOH/METTL16/TNFSF13/SAMD4B/GIGYF2/RPS28/PSMB5/RBM38/ERN1/MAPKAPK2/ZC3HAV1/RPL7A/MRTO4/RPL39/YBX1/SMG6/ZFP36L1/PSMB4/PSMA3/GSPT1/TBRG4/PNRC2/RPL11/AXIN2/EIF3E/ATM/NCBP2/PSMD10/TTC37/PSMB1/PSMD7/PSMB3/PSMC5/TNPO1/KHSRP/RPL22/EXOSC9/LSM2/PSMD11	144
BP	GO:0007051	spindle organization	79/4749	170/18670	2.187e-09	1.751e-06	1.424e-06	ESPL1/AURKB/GPSM2/TPX2/KIFC1/ASPM/KIF4A/STIL/TTK/BIRC5/AURKA/KIF23/WDR62/NEK2/CDC20/SPC25/TACC3/MYBL2/SPAG5/RACGAP1/SAC3D1/PPP2R1A/SMC3/CENPW/CHMP2B/NUF2/HSPA1A/PLK2/KIF11/PLK1/FSD1/TUBB/PSRC1/CCNB1/MAPRE2/CENPE/FBXO5/NUMA1/NDC80/VCP/KIF4B/MSTO1/POC1A/RPS3/SUN2/TUBGCP2/EZR/STMN1/CLASP2/TUBG2/SBDS/PIBF1/CEP192/RAE1/PRC1/UVRAG/RCC1/HAUS5/WRAP73/AUNIP/CHMP1A/MYH9/TUBG1/CCDC69/CHEK2/CHMP2A/CEP72/SMC1A/MAP9/EFHC1/SENP6/AAAS/STARD9/TUBGCP5/CEP97/NUP62/NCOR1/CKAP5/TUBGCP3	79
BP	GO:0045047	protein targeting to ER	60/4749	118/18670	2.664e-09	1.896e-06	1.542e-06	RPL3/RPS8/HSPA5/RPL32/RPS25/RPS12/RPL10A/RPS18/RPS27/RPL35/RPL38/RPS10/RPS3A/RPLP2/RPL21/RPL19/RPL23A/RPS5/RPL36/RPL5/RPL4/RPL30/RPL27A/RPL26/RPS23/RPS6/RPS15/RPL36A/SEC61A2/RPL7/RPL18A/RPS13/RPS20/RPL6/RPS3/RPS15A/RPS27A/SGTA/RPL23/RPS11/RPS19/UBA52/TRAM2/RPS16/RPS9/SEC61B/RPL14/RPL37A/RPL37/RPL29/RPS4X/RPL12/RPSA/RPS28/ZFAND2B/RPL7A/RPL39/RPL11/SPCS3/RPL22	60
BP	GO:1902107	positive regulation of leukocyte differentiation	69/4749	144/18670	4.591e-09	2.752e-06	2.239e-06	EGR3/LIF/CD86/IL18/NLRP3/DUSP10/TRIB1/FES/CD83/CD80/BCL6/IL17A/CBFB/TNFSF4/CCR1/LGALS9/HMGB1/TNF/CSF1/IL2RA/BTN2A2/FOXP3/ZBTB46/IL4R/TOX/PPARGC1B/HLA-G/LILRB4/BTK/GNAS/AXL/CD74/HLX/PPP2R3C/PNP/PTPRC/CYLD/PRKCA/AP3D1/SART1/LILRB2/IL12RB1/CD46/JUN/CA2/IL7R/TNFSF9/KLF10/IL7/IL20/IL4/RIPK2/TYROBP/ZFP36L1/TESC/TRAF6/VNN1/ATP11C/TNFSF11/FOS/SLC9B2/TGFB1/TMEM64/POU4F1/RARA/ZAP70/GATA3/BAD/IL23A	69
BP	GO:0007052	mitotic spindle organization	55/4749	106/18670	4.726e-09	2.752e-06	2.239e-06	AURKB/GPSM2/TPX2/KIFC1/KIF4A/STIL/TTK/BIRC5/AURKA/KIF23/WDR62/NEK2/CDC20/SPC25/TACC3/MYBL2/RACGAP1/SMC3/CHMP2B/NUF2/HSPA1A/PLK2/KIF11/PLK1/FSD1/PSRC1/CCNB1/CENPE/NUMA1/NDC80/VCP/KIF4B/MSTO1/POC1A/SUN2/STMN1/CLASP2/TUBG2/SBDS/PIBF1/CEP192/RAE1/PRC1/RCC1/WRAP73/CHMP1A/TUBG1/CHEK2/CHMP2A/SMC1A/MAP9/EFHC1/AAAS/CEP97/NUP62	55
BP	GO:0006413	translational initiation	86/4749	193/18670	5.495e-09	2.933e-06	2.386e-06	TICRR/RPL3/EIF4EBP1/RPS8/TNF/RPL32/RPS25/RPS12/RPL10A/RPS18/RPS27/MTOR/RPL35/RPL38/RPS10/KLHL25/RPS3A/RPLP2/RPL21/RPL19/RPL23A/RPS5/RPL36/RPL5/RPL4/RPL30/RPL27A/RPL26/RPS23/RPS6/RPS15/RPL36A/PAIP2B/RPL7/EIF5B/RPL18A/RPS13/RPS20/RPL6/ATF4/CTIF/RPS3/RPS15A/EIF2B3/EIF3I/RPS27A/RPL23/RPS11/RPS19/ABCE1/UBA52/RPS16/RPS9/EIF4H/RPL14/RXRA/DHX33/RPL37A/RPL37/FMR1/RPL29/EIF3L/RPS4X/RPL12/RPSA/YTHDF3/EIF3H/EIF2D/EIF2S3/EIF2AK3/EIF4E2/MTFMT/RPS28/EIF3G/MIF4GD/UHMK1/RPL7A/RPL39/GLE1/EIF4E3/DENR/PPP1R15A/RPL11/EIF3E/NCBP2/RPL22	86
BP	GO:1902850	microtubule cytoskeleton organization involved in mitosis	64/4749	131/18670	6.281e-09	3.095e-06	2.518e-06	ESPL1/AURKB/SAPCD2/CENPA/GPSM2/TPX2/KIFC1/KIF4A/STIL/TTK/BIRC5/AURKA/KIF23/WDR62/NEK2/CDC20/NUSAP1/SPC25/TACC3/MYBL2/RACGAP1/SMC3/CHMP2B/NUF2/HSPA1A/PLK2/KIF11/PLK1/FSD1/PSRC1/CCNB1/CENPE/NUMA1/NDC80/ARHGEF2/VCP/KIF4B/MSTO1/POC1A/SUN2/HTT/STMN1/CLASP2/TUBG2/SBDS/PIBF1/CEP192/RAE1/PRC1/RCC1/WRAP73/CHMP1A/ACTR1A/NSFL1C/TUBG1/CHEK2/CHMP2A/SMC1A/MAP9/EFHC1/MCPH1/AAAS/CEP97/NUP62	64
BP	GO:0000070	mitotic sister chromatid segregation	71/4749	151/18670	7.563e-09	3.46e-06	2.815e-06	ESPL1/CENPF/AURKB/KIF2C/CDCA8/KIF14/KIFC1/CDCA5/KIF4A/BUB1B/NCAPG/TTK/CDT1/ZWINT/KIF23/NEK2/TRIP13/CDC20/PTTG1/DLGAP5/NUSAP1/BUB1/TACC3/SPAG5/RACGAP1/NCAPD2/KIF18A/CDC6/PPP2R1A/CHMP2B/NUF2/INCENP/PLK1/PSRC1/CCNB1/CENPE/FBXO5/NUMA1/NDC80/KIF4B/MSTO1/BOD1/DIS3L2/DSCC1/TUBG2/CHTF8/NCAPH/ANAPC11/USP44/PIBF1/PRC1/PHF13/ANAPC1/XRCC3/CHMP1A/NCAPH2/TUBG1/MAD2L2/CHMP2A/KLHL22/APC/SMC1A/CHAMP1/POGZ/ATM/SMC5/PHF23/NUP62/SEH1L/CENPK/DUSP1	71
BP	GO:0071219	cellular response to molecule of bacterial origin	92/4749	212/18670	8.27e-09	3.471e-06	2.824e-06	CXCL13/IL1B/CD86/IL18/CSF2/NLRP3/SGMS1/ICAM1/CD68/IL10/TRIB1/HCK/CD80/IL1RN/MRC1/SIRPA/TIRAP/TNFSF4/HMGB1/TNF/ZFP36/TLR4/CXCL10/LILRA2/SERPINE1/SBNO2/PLSCR4/CMPK2/NFKBIB/PDCD4/TSPO/SRC/PDE4D/CCL3/HAVCR2/PDE4B/AXL/CCR5/UPF1/CD180/CCL2/SIGIRR/PRKCA/ADAMTS13/CXCL9/TLR2/ABCA1/LITAF/NOD2/LILRB2/AICDA/IRAK1/ARG1/SHPK/CXCL2/TLR6/CXCL3/NFKBIA/DEFB114/PRKCE/CEBPB/NFKBIL1/IRF3/PDCD1LG2/ZC3H12A/VIM/LACRT/TBXA2R/TNIP3/SIRT2/RIPK2/TNFRSF1B/CD6/IL36A/DEFA1B/TRAF6/DEFA4/BCR/CARD8/FZD5/PPBP/PPARD/TGFB1/RARA/MAPK1/ADAM9/KLRK1/PTAFR/CX3CR1/TFPI/IL37/TRIM5	92
BP	GO:0071216	cellular response to biotic stimulus	100/4749	236/18670	8.669e-09	3.471e-06	2.824e-06	CXCL13/IL1B/TXNIP/CD86/IL18/CSF2/NLRP3/SGMS1/ICAM1/CD68/IL10/TRIB1/HCK/CD80/IL1RN/MRC1/SIRPA/TIRAP/TNFSF4/CLEC7A/HMGB1/HSPA5/TNF/ZFP36/TLR4/CXCL10/LILRA2/SERPINE1/SBNO2/PLSCR4/CMPK2/NFKBIB/PDCD4/TSPO/SRC/PDE4D/BTK/CCL3/HAVCR2/PDE4B/AXL/CCR5/UPF1/CD180/CCL2/SIGIRR/PRKCA/ADAMTS13/CXCL9/TLR2/ABCA1/LITAF/NOD2/LILRB2/AICDA/IRAK1/DDIT3/ARG1/SHPK/CXCL2/TLR6/CXCL3/NFKBIA/DEFB114/PRKCE/CEBPB/NFKBIL1/IRF3/PDCD1LG2/ZC3H12A/VIM/LACRT/TBXA2R/EME1/TNIP3/SIRT2/EIF2AK3/RIPK2/TNFRSF1B/CD6/IL36A/DEFA1B/TRAF6/DEFA4/BCR/SMC1A/CARD8/FZD5/PPBP/PPARD/TGFB1/RARA/MAPK1/ADAM9/KLRK1/PTAFR/CX3CR1/TFPI/IL37/TRIM5	100
BP	GO:0140014	mitotic nuclear division	109/4749	264/18670	1.062e-08	3.836e-06	3.121e-06	ESPL1/CENPF/AURKB/PKMYT1/IL1B/KIF2C/CDCA8/TPX2/KIF14/ANLN/KIFC1/CDCA5/KIF4A/UBE2C/BUB1B/NCAPG/TTK/MKI67/CDT1/BIRC5/ZWINT/AURKA/KIF23/KIF20B/NEK2/TRIP13/CDC20/PTTG1/DLGAP5/NUSAP1/BUB1/TACC3/MYBL2/SPAG5/RACGAP1/NCAPD2/KIF18A/CDC6/PPP2R1A/UBE2S/SMC3/CHMP2B/NUF2/INCENP/HSPA1A/KIF11/PLK1/CDC25C/PSRC1/CCNB1/CENPE/FBXO5/NUMA1/NDC80/KIF4B/PDXP/MSTO1/BOD1/PHIP/TOM1L2/DIS3L2/CLASP2/DSCC1/TUBG2/CHTF8/NCAPH/ANAPC11/CHEK1/USP44/PIBF1/CEP192/PRC1/PHF13/RCC1/ANAPC1/XRCC3/WRAP73/SIRT2/CHMP1A/CDC14B/NCAPH2/NSFL1C/TUBG1/MAD2L2/CHEK2/CHMP2A/INSR/KLHL22/FGF8/APC/SMC1A/CHAMP1/MAP9/PPP1R9B/SIRT7/POGZ/ATM/AAAS/SMC5/PHF23/TGFB1/TOM1L1/CEP97/PDGFB/NUP62/SEH1L/KLHDC8B/CENPK/DUSP1	109
BP	GO:0090150	establishment of protein localization to membrane	131/4749	332/18670	1.078e-08	3.836e-06	3.121e-06	TP73/RAB31/ZDHHC12/RPL3/YWHAH/CDK5/REEP2/BBS2/YWHAE/GORASP1/TP63/YWHAZ/RPS8/HSPA5/E2F1/RPL32/RPS25/RPS12/BAX/RPL10A/RPS18/RPS27/PMAIP1/RPL35/RPL38/RPS10/RPS3A/RPLP2/RPL21/RPL19/RPL23A/RPS5/RPL36/MOAP1/GRIPAP1/SEC16A/RPL5/RPL4/RPL30/RPL27A/SFN/RPL26/RPS23/RPS6/SNAP47/RPS15/BMF/SDCBP/TIMM10/RPL36A/SEC61A2/RPL7/PAK1/RPL18A/RPS13/GGA2/RPS20/RPL6/RPS3/RPS15A/PDCD5/RPS27A/COX18/MICALL1/NMT1/ATP1B1/STX1B/SGTA/BID/RPL23/SPTBN1/TIMM22/RPS11/RPS19/RILPL2/ROMO1/PRKCI/RFTN1/UBA52/TRAM2/TFDP2/RPS16/SCRIB/ZDHHC24/RPS9/SEC61B/RPL14/RPL37A/YWHAQ/CHP1/RPL37/ERBB2/RPL29/VAMP3/ZDHHC3/GRIN3B/RPS4X/RPL12/RABGEF1/RPSA/SYNE3/BRAF/PEX3/PEX5/RPS28/PRNP/ZDHHC4/ZFAND2B/RPL7A/GOPC/RPL39/ZDHHC9/ZDHHC2/ZDHHC7/RAB34/RPL11/TOMM22/AGK/NCF1/STOM/CNST/NDUFA13/GDI1/USP17L2/TIMM9/RPL22/BAD/SSR2/FYN/REEP1/UBL4A	131
BP	GO:0072599	establishment of protein localization to endoplasmic reticulum	60/4749	122/18670	1.35e-08	4.552e-06	3.704e-06	RPL3/RPS8/HSPA5/RPL32/RPS25/RPS12/RPL10A/RPS18/RPS27/RPL35/RPL38/RPS10/RPS3A/RPLP2/RPL21/RPL19/RPL23A/RPS5/RPL36/RPL5/RPL4/RPL30/RPL27A/RPL26/RPS23/RPS6/RPS15/RPL36A/SEC61A2/RPL7/RPL18A/RPS13/RPS20/RPL6/RPS3/RPS15A/RPS27A/SGTA/RPL23/RPS11/RPS19/UBA52/TRAM2/RPS16/RPS9/SEC61B/RPL14/RPL37A/RPL37/RPL29/RPS4X/RPL12/RPSA/RPS28/ZFAND2B/RPL7A/RPL39/RPL11/SPCS3/RPL22	60
BP	GO:0010498	proteasomal protein catabolic process	175/4749	477/18670	2.441e-08	7.147e-06	5.814e-06	ZNRF1/AURKB/PBK/CCNF/RNF144A/KIF14/UBE2C/BUB1B/CDK1/AURKA/TRIB1/CDC20/PTTG1/UBE2A/RFFL/PML/KCTD17/UBE2S/FBXL19/CBFA2T3/HSPA5/SDF2L1/HSPA1A/PLK2/ECSCR/DERL1/SPSB1/UBE2B/PLK1/UBXN6/DET1/TRIM25/PMAIP1/GPX1/WNT10B/SYVN1/AMN1/SMAD7/RYBP/CCNB1/KCTD5/UBE2H/FBXO5/UBE3D/TNFAIP1/POMT2/PSMD8/FBXL18/ARRB1/VCP/DNAJB12/SDCBP/CDK2/CLU/USP19/UBB/PSMD1/PSMD2/WWTR1/HERPUD1/FBXL14/PSMF1/N4BP1/UBXN1/FBXO48/NPLOC4/RPS27A/RNF40/FBXO27/FBXO31/UBE4A/SGTA/SMURF1/PINK1/UBE2G2/PIAS1/BCAP31/RAD23B/RNF187/UBA52/ERCC8/TRIM13/DVL1/PSMD9/PCNP/SEC61B/GBA/PSMA5/FBXL8/DDIT3/RCN3/MAEA/SUMO1/ANAPC11/RNF19B/RNF216/PARK7/FMR1/PSMB7/UBE3A/JKAMP/FBXW11/TOPORS/USP44/RAD23A/PSMD5/SCO1/SDF2/EDEM2/CUL5/SPSB2/USP5/ARNTL/UCHL5/SIAH2/ANAPC1/RNF7/GSK3A/PSME2/BRSK2/PRPF19/BTRC/UBQLN2/BAG2/CD2AP/SIRT2/FBXL4/ZFAND2A/PSMB5/KCTD13/ZFAND2B/FBXO9/NSFL1C/RNF139/UBR2/TMEM67/GCLC/PSMB4/RNF121/MAP1A/NUPR1/KLHL22/OSBPL7/PSMA3/MTA1/FBXL22/FBXL15/RPL11/FBXL20/TMUB2/FBXO44/UBXN11/PSMD10/HERC2/CUL4A/PSMB1/PSMD7/HECTD3/GLMN/TMF1/PSMB3/UCHL1/DNAJB2/CDC16/PSMC5/UBAC2/CRBN/FBXO4/RNF186/TRIM9/TRIB3/NHLRC3/UBE2W/PSMD11/SIRT1	175
BP	GO:0042110	T cell activation	171/4749	464/18670	2.451e-08	7.147e-06	5.814e-06	EGR1/EGR3/EBI3/IL1B/CD86/SDC4/IL18/JAG2/CD276/RELB/IL21/NLRP3/ICAM1/DUSP10/ADORA2A/IL10/BATF/CD83/SRF/CD80/RAC1/PDCD1/PTPN6/IRF4/BCL3/BCL6/TNFRSF18/TREX1/CBFB/SIRPA/TNFSF4/TFRC/CLEC7A/LGALS3/GPNMB/CEACAM1/PRELID1/LGALS9/PRDM1/HMGB1/TNFRSF4/GSN/IL2RA/BAX/BTN2A2/TNFRSF21/MTOR/FOXP3/CD1C/CTLA4/STAT3/IL4R/RSAD2/SMAD7/DOCK8/CCR6/RIPK3/CCR2/SRC/HLA-G/SIT1/LILRB4/RPS6/TIGIT/PTGER4/HAVCR2/CD74/PAK1/APBB1IP/KAT2A/CD1D/GRAP2/RPS3/EFNB1/CLEC4G/LY9/HLX/RUNX2/LGALS1/SATB1/CCL2/PNP/PAK3/ZFP36L2/RORC/PREX1/DNAJA3/HLA-DPA1/PATZ1/PTPRC/CYLD/CORO1A/HLA-E/CD47/AIF1/DUSP22/LAT/AP3D1/SART1/MICA/CD7/NOD2/LILRB2/IL12RB1/FKBP1A/SLA2/THY1/ARG1/LAG3/IL18R1/RAB27A/CD46/FZD8/CLEC4D/ERBB2/CD44/RAC2/CDH26/CD151/AZI2/CEBPB/IL7R/IDO1/DTX1/HLA-DMB/TNFSF9/NLRC3/PDCD1LG2/ZC3H12A/NRARP/IL7/ITK/CD3E/DLG5/CCDC88B/CARD11/IL4/NHEJ1/MYH9/PRNP/RIPK2/TNFRSF1B/NCAPH2/PAX1/CD6/ZFP36L1/HLA-DPB1/TRAF6/VNN1/THEMIS/TNFSF11/FZD5/RAG2/TGFB1/CDC42/WAS/GLMN/JAK3/RARA/HHLA2/KLRK1/ZAP70/ZFPM1/GATA3/P2RX7/LRRC32/RPL22/BAD/FYN/PAK2/IL23A	171
BP	GO:0000956	nuclear-transcribed mRNA catabolic process	89/4749	207/18670	2.454e-08	7.147e-06	5.814e-06	HELZ2/RPL3/PPP2R1A/RPS8/ZFP36/RPL32/RPS25/RPS12/RPL10A/RPS18/RPS27/SMG5/RPL35/RPL38/RPS10/RPS3A/RPLP2/RPL21/RPL19/RPL23A/RPS5/RPL36/RPL5/RPL4/RPL30/RPL27A/RPL26/RPS23/RNPS1/RPS6/RPS15/RPL36A/TNRC6B/PELO/RPL7/SMG9/RPL18A/RPS13/RPS20/RPL6/CTIF/RPS3/DCPS/RPS15A/UPF1/RPS27A/ZFP36L2/MAGOHB/RPL23/RPS11/RPS19/DIS3L2/CNOT3/UBA52/RPS16/PPP2CA/PAN3/RPS9/RPL14/RPL37A/EDC4/RPL37/EXOSC2/RPL29/RPS4X/SMG8/ZC3H12A/RPL12/UPF3A/CNOT7/RPSA/MAGOH/SAMD4B/RPS28/RPL7A/MRTO4/RPL39/SMG6/ZFP36L1/GSPT1/PNRC2/RPL11/EIF3E/ATM/NCBP2/TTC37/RPL22/EXOSC9/LSM2	89
BP	GO:0002237	response to molecule of bacterial origin	133/4749	343/18670	2.904e-08	8.087e-06	6.579e-06	CXCL13/IL1B/NOTCH1/CD86/IL18/CSF2/CSF2RB/NLRP3/SGMS1/ICAM1/DUSP10/CASP9/CD68/IL10/TRIB1/ACP5/HCK/CD80/IL1RN/MRC1/SIRPA/TIRAP/TNFSF4/TIMP4/LGALS9/HMGB1/NFKB2/TNF/ZFP36/IRF5/TLR4/CXCL10/LILRA2/SERPINE1/SBNO2/PLSCR4/CMPK2/NFKBIB/CARD9/CNP/PDCD4/TSPO/SRC/GGT1/PRDX3/HNRNPA0/PDE4D/CCL3/PTGER4/IL12RB2/HAVCR2/PDE4B/AXL/CCR5/SMAD6/UPF1/IRAK3/CD180/CCL2/SIGIRR/PRKCA/LIAS/ADAMTS13/CXCL9/TLR2/ABCA1/LITAF/NOD2/LILRB2/AICDA/IRAK1/ARG1/SHPK/LTA/CXCL2/CNR1/TLR6/CXCL3/JUN/CYP27B1/NFKBIA/DEFB114/PRKCE/CEBPB/PTGER2/NFKBIL1/IDO1/MPO/IRF3/PDCD1LG2/ZC3H12A/VIM/LACRT/TBXA2R/LOXL1/TNIP3/PTGER1/IL13/ADM/SIRT2/S100A8/RIPK2/TNFRSF1B/F2R/MAPKAPK2/FER/CD6/MGST2/IL36A/DEFA1B/AKIRIN2/TRAF6/DEFA4/BCR/CARD8/HPGD/IL10RA/FZD5/PPBP/FOS/PPARD/TGFB1/RARA/MAPK1/ADAM9/KLRK1/CD96/PTAFR/P2RX7/CX3CR1/TFPI/IL37/TRIM5	133
BP	GO:0071222	cellular response to lipopolysaccharide	88/4749	205/18670	3.209e-08	8.567e-06	6.969e-06	CXCL13/IL1B/CD86/IL18/CSF2/NLRP3/SGMS1/ICAM1/CD68/IL10/TRIB1/HCK/CD80/IL1RN/MRC1/SIRPA/TNFSF4/HMGB1/TNF/ZFP36/TLR4/CXCL10/LILRA2/SERPINE1/SBNO2/PLSCR4/CMPK2/NFKBIB/PDCD4/TSPO/SRC/PDE4D/CCL3/HAVCR2/PDE4B/AXL/CCR5/UPF1/CD180/CCL2/SIGIRR/PRKCA/ADAMTS13/CXCL9/TLR2/ABCA1/LITAF/NOD2/LILRB2/AICDA/IRAK1/ARG1/SHPK/CXCL2/CXCL3/NFKBIA/DEFB114/PRKCE/CEBPB/NFKBIL1/IRF3/PDCD1LG2/ZC3H12A/VIM/LACRT/TBXA2R/TNIP3/RIPK2/TNFRSF1B/CD6/IL36A/DEFA1B/TRAF6/DEFA4/BCR/CARD8/PPBP/PPARD/TGFB1/RARA/MAPK1/ADAM9/KLRK1/PTAFR/CX3CR1/TFPI/IL37/TRIM5	88
BP	GO:1902105	regulation of leukocyte differentiation	110/4749	272/18670	3.459e-08	8.864e-06	7.211e-06	EGR3/LIF/IRF7/CD86/IL18/HMGB3/NLRP3/DUSP10/TRIB1/FES/CD83/RASSF2/CD80/PTPN6/IRF4/BCL6/IL17A/TNFRSF18/CBFB/TNFSF4/CCR1/CEACAM1/PRELID1/LGALS9/PRDM1/HMGB1/TNF/CSF1/IL2RA/TLR4/BTN2A2/PIAS3/MTOR/FOXP3/ESRRA/CTLA4/ZBTB46/IL4R/SMAD7/TOX/CCR2/PPARGC1B/TFE3/HLA-G/LILRB4/BTK/GNAS/CCL3/AXL/CD74/KAT2A/HLX/PPP2R3C/PNP/ZFP36L2/PGLYRP3/PTPRC/CYLD/PRKCA/NFAM1/AP3D1/SART1/LILRB2/IL12RB1/LAG3/CD46/JUN/TOB2/ERBB2/CA2/CEBPB/IL7R/DTX1/TNFSF9/ZC3H12A/TMEM176B/NRARP/KLF10/IL7/IL20/BGLAP/SFRP1/CARD11/ADIPOQ/IL4/RIPK2/TYROBP/ZFP36L1/TESC/TRAF6/VNN1/ATP11C/TNFSF11/FOS/SLC9B2/ZNF675/TGFB1/TMEM64/CUL4A/POU4F1/JAK3/RARA/MIR17HG/ZAP70/ZFPM1/GATA3/TCTA/BAD/NME2/IL23A	110
BP	GO:1903039	positive regulation of leukocyte cell-cell adhesion	92/4749	218/18670	4.237e-08	1.044e-05	8.493e-06	EGR3/EBI3/IL1B/CD86/IL18/CD276/IL21/NR4A3/NLRP3/ICAM1/DUSP10/CD83/CD80/RAC1/PDCD1/PTPN6/BCL6/CBFB/SIRPA/TNFSF4/TFRC/LGALS9/HMGB1/TNF/IL2RA/BTN2A2/FOXP3/CTLA4/IL4R/DOCK8/CCR2/SRC/HLA-G/LILRB4/HAVCR2/CD74/PAK1/CD1D/GRAP2/RPS3/EFNB1/HLX/LGALS1/CCL2/PNP/PAK3/DNAJA3/HLA-DPA1/PTPRC/CYLD/CORO1A/HLA-E/CD47/AIF1/AP3D1/SART1/NOD2/LILRB2/IL12RB1/IRAK1/THY1/CD46/CD44/IL7R/HLA-DMB/TNFSF9/PDCD1LG2/IL7/CD3E/CCDC88B/CARD11/IL4/RIPK2/CD6/HLA-DPB1/TRAF6/VNN1/TNFSF11/TGFB1/CDC42/HAS2/JAK3/RARA/HHLA2/KLRK1/ZAP70/GATA3/PTAFR/BAD/FYN/PAK2/IL23A	92
BP	GO:0097193	intrinsic apoptotic signaling pathway	115/4749	289/18670	4.878e-08	1.157e-05	9.416e-06	PPIF/SKIL/TP73/CDKN1A/SGMS1/CASP9/E2F2/PHLDA3/GSKIP/MELK/CHAC1/BCL3/PLAUR/PERP/ZNF385A/MLLT11/DAPK2/MCL1/ENO1/DNAJA1/MMP9/TP63/SFPQ/PML/SERINC3/TNF/E2F1/MSH6/HSPA1A/CRIP1/RRM2B/BRCA2/NOL3/BAX/PTPN1/PMAIP1/GPX1/PLAGL2/SYVN1/MSX1/RIPK3/SRC/IFI6/MOAP1/SNAI1/HMOX1/ARHGEF2/SFN/RPL26/ATP2A1/BMF/CLU/UBB/CD74/URI1/HERPUD1/ATF4/RPS3/SGPP1/BID/TNFRSF10B/MAP3K5/PINK1/CYLD/BCAP31/DDIT4/FIGNL1/BCL2A1/TAF9B/MUC1/BAK1/TMEM117/DDIT3/BDKRB2/WWOX/STYXL1/PARK7/STK25/BCL2L12/TOPORS/CD44/MYBBP1A/TXNDC12/CEBPB/CUL5/AEN/BCL2L1/PTPMT1/BRSK2/IFI16/TRAF2/PIAS4/EIF2AK3/S100A8/ERN1/CIDEB/TNFRSF1B/CHEK2/NUPR1/RRP8/PPP1R15A/RPL11/VNN1/XPA/ATM/SHISA5/CUL4A/POU4F1/NDUFA13/PDX1/BAD/RNF186/TRIB3/RAD9A/SIRT1	115
BP	GO:0032496	response to lipopolysaccharide	128/4749	330/18670	5.141e-08	1.176e-05	9.568e-06	CXCL13/IL1B/NOTCH1/CD86/IL18/CSF2/CSF2RB/NLRP3/SGMS1/ICAM1/DUSP10/CASP9/CD68/IL10/TRIB1/ACP5/HCK/CD80/IL1RN/MRC1/SIRPA/TIRAP/TNFSF4/TIMP4/LGALS9/HMGB1/NFKB2/TNF/ZFP36/TLR4/CXCL10/LILRA2/SERPINE1/SBNO2/PLSCR4/CMPK2/NFKBIB/CNP/PDCD4/TSPO/SRC/GGT1/PRDX3/HNRNPA0/PDE4D/CCL3/PTGER4/IL12RB2/HAVCR2/PDE4B/AXL/CCR5/SMAD6/UPF1/IRAK3/CD180/CCL2/SIGIRR/PRKCA/LIAS/ADAMTS13/CXCL9/TLR2/ABCA1/LITAF/NOD2/LILRB2/AICDA/IRAK1/ARG1/SHPK/LTA/CXCL2/CNR1/CXCL3/JUN/CYP27B1/NFKBIA/DEFB114/PRKCE/CEBPB/PTGER2/NFKBIL1/IDO1/MPO/IRF3/PDCD1LG2/ZC3H12A/VIM/LACRT/TBXA2R/LOXL1/TNIP3/PTGER1/IL13/ADM/S100A8/RIPK2/TNFRSF1B/F2R/MAPKAPK2/FER/CD6/MGST2/IL36A/DEFA1B/AKIRIN2/TRAF6/DEFA4/BCR/CARD8/HPGD/IL10RA/PPBP/FOS/PPARD/TGFB1/RARA/MAPK1/ADAM9/KLRK1/CD96/PTAFR/P2RX7/CX3CR1/TFPI/IL37/TRIM5	128
BP	GO:0007059	chromosome segregation	125/4749	321/18670	5.654e-08	1.249e-05	1.016e-05	ESPL1/CENPF/AURKB/KIF2C/CDCA8/KIF14/SKA1/KIFC1/HJURP/CDCA5/KIF4A/BUB1B/FAM83D/NCAPG/GEM/TTK/PMF1/MKI67/CDT1/TOP2A/BIRC5/ZWINT/KIF23/TOP3A/NEK2/TRIP13/CDC20/PTTG1/DLGAP5/ESCO2/SKA3/NUSAP1/SPC25/BUB1/TACC3/SPAG5/RACGAP1/NCAPD2/KIF18A/SFPQ/CDC6/PPP2R1A/SMC3/CENPW/CHMP2B/SYCE3/NUF2/INCENP/UBE2B/USP9X/PLK1/FEN1/PSRC1/NR3C1/CCNB1/RMI2/CDCA2/CENPE/FBXO5/NUMA1/NDC80/UBE2I/CENPT/KIF4B/DMC1/MSTO1/BOD1/CCNE2/RPS3/TERF1/DIS3L2/HELQ/DSCC1/TUBG2/RECQL5/BANF1/CHTF8/TTL/NCAPH/CENPN/ANAPC11/ERCC2/REC8/SLC25A5/USP44/PIBF1/ECT2/PRC1/PHF13/BEX4/UVRAG/OIP5/STAG3/RCC1/ANAPC1/XRCC3/EME1/DDX11/SYCE2/SIRT2/CHMP1A/SETDB2/NCAPH2/TUBG1/MAD2L2/ANKRD31/CHMP2A/KLHL22/APC/SMC1A/CHAMP1/AXIN2/POGZ/ATM/MLH3/SMC5/PHF23/CDC42/RNF212/TRAPPC12/NUP62/SEH1L/KLHDC8B/CENPK/DUSP1	125
BP	GO:0034341	response to interferon-gamma	85/4749	199/18670	7.161e-08	1.529e-05	1.244e-05	CDC42EP4/IRF7/PPARG/ICAM1/CCL20/CCL3L3/HCK/FCGR1B/IRF4/GAPDH/MRC1/ZYX/SIRPA/CCL22/OAS2/GBP2/LGALS9/UBD/PML/IFI30/IRF5/GSN/TLR4/HLA-DQB2/TRIM25/MT2A/TRIM26/ACTG1/PARP14/FCGR1A/IFITM2/HLA-H/SOCS3/HLA-G/TRIM62/CCL3/CAMK2A/BST2/OASL/CCL2/TRIM22/CALCOCO2/CCL17/HLA-DPA1/PIAS1/HLA-E/CD47/AIF1/ADAMTS13/CCL18/TLR2/CXCL16/HLA-DRA/CD58/IL12RB1/IFITM3/TXK/IFITM1/MID1/SLC26A6/ARG1/SUMO1/CYP27B1/CD44/CAMK2G/VAMP3/IRF3/VIM/HLA-DQA2/OAS1/DAPK1/IFNGR1/CAMK2D/HLA-DPB1/CCL23/STAT1/CCL7/GBP4/CCL15/WAS/HLA-DRB1/PTAFR/RAB12/JAK1/TRIM5	85
BP	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	155/4749	419/18670	8.297e-08	1.662e-05	1.352e-05	ZNRF1/AURKB/PBK/CCNF/RNF144A/KIF14/UBE2C/BUB1B/CDK1/AURKA/TRIB1/CDC20/PTTG1/UBE2A/RFFL/PML/KCTD17/UBE2S/FBXL19/CBFA2T3/HSPA5/HSPA1A/PLK2/DERL1/SPSB1/UBE2B/PLK1/DET1/TRIM25/WNT10B/SYVN1/AMN1/SMAD7/RYBP/CCNB1/KCTD5/UBE2H/FBXO5/UBE3D/TNFAIP1/PSMD8/FBXL18/ARRB1/VCP/DNAJB12/SDCBP/CDK2/CLU/USP19/UBB/PSMD1/PSMD2/WWTR1/HERPUD1/FBXL14/PSMF1/N4BP1/UBXN1/FBXO48/NPLOC4/RPS27A/FBXO27/FBXO31/UBE4A/SGTA/SMURF1/UBE2G2/PIAS1/BCAP31/RAD23B/RNF187/UBA52/ERCC8/TRIM13/DVL1/PSMD9/PCNP/SEC61B/GBA/PSMA5/FBXL8/DDIT3/MAEA/SUMO1/ANAPC11/RNF19B/RNF216/PARK7/PSMB7/UBE3A/JKAMP/FBXW11/TOPORS/USP44/RAD23A/PSMD5/EDEM2/CUL5/SPSB2/USP5/ARNTL/UCHL5/SIAH2/ANAPC1/RNF7/GSK3A/PSME2/BTRC/UBQLN2/CD2AP/SIRT2/FBXL4/ZFAND2A/PSMB5/KCTD13/ZFAND2B/FBXO9/NSFL1C/UBR2/TMEM67/GCLC/PSMB4/RNF121/MAP1A/KLHL22/PSMA3/MTA1/FBXL22/FBXL15/RPL11/FBXL20/TMUB2/FBXO44/UBXN11/PSMD10/HERC2/CUL4A/PSMB1/PSMD7/HECTD3/GLMN/PSMB3/UCHL1/DNAJB2/CDC16/PSMC5/CRBN/FBXO4/RNF186/TRIM9/TRIB3/NHLRC3/UBE2W/PSMD11/SIRT1	155
BP	GO:0006605	protein targeting	159/4749	432/18670	8.304e-08	1.662e-05	1.352e-05	BNIP3L/ZDHHC12/RPL3/CDK5/MPV17/YWHAE/YWHAZ/RPS8/HSPA5/AKAP5/RPL32/RPS25/RPS12/USP9X/RPL10A/RPS18/RPS27/TIMM17A/RPL35/RPL38/RPS10/RPS3A/BAG4/GDAP1/RPLP2/RPL21/RPL19/RPL23A/TSPO/SORL1/USP36/SAE1/RPS5/RPL36/RPL5/RPL4/RPL30/RPL27A/RPL26/MON1B/RPS23/RPS6/SLC27A2/RPS15/SDCBP/TIMM10/CLU/RPL36A/SEC61A2/UBB/RPL7/PAK1/RPL18A/RPS13/RPS20/RPL6/BAP1/HMGCL/EPHX2/RPS3/RPS15A/PDCD5/ACOX2/TYSND1/RPS27A/PARL/MICALL1/NUCB1/SYNJ2BP/M6PR/HPS4/SGTA/SMURF1/BID/RPL23/PINK1/TIMM22/RPS11/RPS19/ACOT8/TIMM50/ROMO1/PRKCI/CACNG3/UBA52/TRAM2/AP3D1/RPS16/PAN3/ZDHHC24/RPS9/SEC61B/GRPEL1/HGS/RPL14/RPL37A/RAB27A/YWHAQ/CHP1/RPL37/AMACR/NCOA4/PEX2/ERBB2/RPL29/RAC2/ZDHHC3/RPS4X/AP4M1/RPL12/BAG3/IMMP1L/RABGEF1/GSK3A/RPSA/RHOU/PEX3/UBL5/PEX5/VTI1B/SYNGR1/MIPEP/RPS28/PRNP/ZDHHC4/ZFAND2B/RPL7A/RPL39/HSPA1L/ZDHHC9/PAM16/ZDHHC2/PIK3R4/ZDHHC7/RPL11/VPS13D/TOMM22/GSTK1/AGK/FZD5/NCF1/NUDT19/PECR/STOM/CHCHD4/SPCS3/PEX13/NDUFA13/GDI1/USP17L2/TIMM9/PEX1/SREBF2/RPL22/SSR2/DECR2/FYN/MGARP/ZFAND6	159
BP	GO:0070972	protein localization to endoplasmic reticulum	67/4749	147/18670	8.962e-08	1.74e-05	1.415e-05	RPL3/RPS8/HSPA5/RPL32/RPS25/RPS12/RPL10A/RPS18/RPS27/RPL35/RPL38/RPS10/RPS3A/RPLP2/RPL21/RPL19/RPL23A/RPS5/RPL36/SEC16A/RPL5/RPL4/RPL30/RPL27A/RPL26/RPS23/KDELR2/RPS6/RPS15/RPL36A/SEC61A2/RPL7/RPL18A/RPS13/RPS20/RPL6/RPS3/RPS15A/RPS27A/SGTA/RPL23/RPS11/RPS19/BCAP31/UBA52/TRAM2/RPS16/INSIG1/RPS9/SEC61B/RPL14/RPL37A/RPL37/GBF1/RPL29/RPS4X/RPL12/RPSA/RPS28/ZFAND2B/RPL7A/RPL39/PPP1R15A/RPL11/SPCS3/UBAC2/RPL22	67
BP	GO:0000075	cell cycle checkpoint	90/4749	216/18670	1.198e-07	2.215e-05	1.802e-05	CENPF/AURKB/GTSE1/E2F7/E2F8/BUB1B/TTK/TICRR/CDK1/CDT1/CDKN1A/DTL/TOP2A/ZWINT/AURKA/CDKN2B/DOT1L/TRIP13/CDC20/TREX1/CLSPN/BUB1/ZNF385A/CDC6/PML/E2F1/PLK2/BAX/PLK1/CDC25C/GADD45A/PEA15/CCNB1/NDC80/SFN/RPL26/TP53BP1/RPS6/CDC45/CDK2/CRY1/ORC1/RFWD3/TOPBP1/FBXO31/CARM1/CNOT3/TIPRL/TIMELESS/TFDP2/MUC1/FEM1B/MDM4/TAOK3/BRCC3/WDR76/CHEK1/USP44/SOX11/RBL2/BCL2L1/XRCC3/ZNF830/EME1/PRPF19/CNOT7/MDC1/CDC5L/DNA2/ETAA1/GIGYF2/CDC14B/GML/NAE1/MAD2L2/ATR/CHEK2/KLHL22/APC/ATM/TGFB1/NSUN2/CUL4A/CCND1/SYF2/USP17L2/FBXO4/TIPIN/RAD9A/DUSP1	90
BP	GO:0000819	sister chromatid segregation	81/4749	189/18670	1.21e-07	2.215e-05	1.802e-05	ESPL1/CENPF/AURKB/KIF2C/CDCA8/KIF14/KIFC1/CDCA5/KIF4A/BUB1B/NCAPG/TTK/CDT1/TOP2A/ZWINT/KIF23/NEK2/TRIP13/CDC20/PTTG1/DLGAP5/ESCO2/NUSAP1/BUB1/TACC3/SPAG5/RACGAP1/NCAPD2/KIF18A/SFPQ/CDC6/PPP2R1A/SMC3/CHMP2B/NUF2/INCENP/PLK1/FEN1/PSRC1/CCNB1/RMI2/CENPE/FBXO5/NUMA1/NDC80/KIF4B/MSTO1/BOD1/DIS3L2/DSCC1/TUBG2/CHTF8/NCAPH/ANAPC11/REC8/USP44/PIBF1/PRC1/PHF13/STAG3/ANAPC1/XRCC3/DDX11/CHMP1A/NCAPH2/TUBG1/MAD2L2/CHMP2A/KLHL22/APC/SMC1A/CHAMP1/AXIN2/POGZ/ATM/SMC5/PHF23/NUP62/SEH1L/CENPK/DUSP1	81
BP	GO:0051098	regulation of binding	140/4749	373/18670	1.293e-07	2.302e-05	1.872e-05	CRMP1/TWIST1/LIF/AURKB/HJURP/CDCA5/CDT1/PPARG/ITGA2/AURKA/GPSM1/PTPRF/IL10/IFIT1/DOT1L/KLF4/NEK2/PHLDA2/TTBK1/IRF4/BCL3/PLAUR/TIRAP/CAMK1/CDK5/ANXA2P2/LGALS3/MMP9/GMNN/SYAP1/HMGB1/HSPA5/E2F1/PLK2/SKI/DERL1/BAX/ZBTB7C/PLK1/SPPL3/ANXA2/MSX1/SORL1/SRC/BTBD1/HMOX1/DTX3L/TIAM1/CTHRC1/MBD2/TMC8/ARRB1/PIM2/GREM2/PRMT7/SRI/SUMO3/ENHO/PER2/HIP1R/TCF7L2/CARM1/ZNF304/CYLD/LRPAP1/STK3/STMN1/TFIP11/PLXND1/DVL1/FLOT1/VTN/S100A10/PPP2CA/BAK1/ACD/TRAF4/FKBP1A/LRP1/PLCL2/DTNBP1/DDIT3/TAF10/SUMO1/PARK7/JUN/FMR1/ERCC2/EPB41L5/SPON1/STPG1/NFKBIA/CRK/CTSZ/SOX11/ADAM15/RAPGEF2/CCPG1/SNAPIN/IFI16/BTAF1/BAG2/DDX11/TRAF2/SIRT2/CFHR1/ADIPOQ/RIPK2/EDF1/LDLRAP1/EPB41/MAD2L2/AIDA/P2RY1/TRAF6/CCL23/ARF6/CYP2D6/IFIT2/RPL11/RALB/TNFSF11/EIF3E/NUCKS1/ZNF675/MITD1/ID1/TGFB1/POU4F1/ADNP/RARA/DNAJB2/PDGFB/ZFPM1/GATA3/CRBN/PDX1/ADD2/TRIB3/ACTB	140
BP	GO:0050870	positive regulation of T cell activation	85/4749	202/18670	1.589e-07	2.715e-05	2.209e-05	EGR3/EBI3/IL1B/CD86/IL18/CD276/IL21/NLRP3/DUSP10/CD83/CD80/RAC1/PDCD1/PTPN6/BCL6/CBFB/SIRPA/TNFSF4/TFRC/LGALS9/HMGB1/IL2RA/BTN2A2/FOXP3/CTLA4/IL4R/DOCK8/CCR2/SRC/HLA-G/LILRB4/HAVCR2/CD74/PAK1/CD1D/GRAP2/RPS3/EFNB1/HLX/LGALS1/CCL2/PNP/PAK3/DNAJA3/HLA-DPA1/PTPRC/CYLD/CORO1A/HLA-E/CD47/AIF1/AP3D1/SART1/NOD2/LILRB2/IL12RB1/THY1/CD46/IL7R/HLA-DMB/TNFSF9/PDCD1LG2/IL7/CD3E/CCDC88B/CARD11/IL4/RIPK2/CD6/HLA-DPB1/TRAF6/VNN1/TNFSF11/TGFB1/CDC42/JAK3/RARA/HHLA2/KLRK1/ZAP70/GATA3/BAD/FYN/PAK2/IL23A	85
BP	GO:1903037	regulation of leukocyte cell-cell adhesion	118/4749	304/18670	1.61e-07	2.715e-05	2.209e-05	EGR3/EBI3/IL1B/CD86/SDC4/IL18/CD276/IL21/NR4A3/NLRP3/WNK1/ICAM1/DUSP10/ADORA2A/IL10/CD83/KLF4/CD80/RAC1/PDCD1/PTPN6/BCL6/CBFB/SIRPA/TNFSF4/TFRC/LGALS3/GPNMB/CEACAM1/LGALS9/HMGB1/TNF/IL2RA/BTN2A2/TNFRSF21/FOXP3/ADTRP/CTLA4/IL4R/SMAD7/DOCK8/CCR2/SRC/HLA-G/LILRB4/TIGIT/HAVCR2/CD74/PAK1/CD1D/GRAP2/RPS3/EFNB1/CLEC4G/HLX/LGALS1/CCL2/PNP/PAK3/DNAJA3/HLA-DPA1/PTPRC/CYLD/CORO1A/HLA-E/CD47/AIF1/DUSP22/AP3D1/SART1/NOD2/LILRB2/IL12RB1/IRAK1/THY1/ARG1/LAG3/CD46/ERBB2/CD44/CEBPB/IL7R/IDO1/DTX1/HLA-DMB/TNFSF9/PDCD1LG2/ZC3H12A/NRARP/IL7/CD3E/DLG5/CCDC88B/CARD11/IL4/PRNP/RIPK2/CD6/HLA-DPB1/TRAF6/VNN1/TNFSF11/TGFB1/CDC42/HAS2/GLMN/JAK3/RARA/HHLA2/KLRK1/ZAP70/GATA3/PTAFR/LRRC32/BAD/FYN/PAK2/IL23A	118
BP	GO:0022409	positive regulation of cell-cell adhesion	102/4749	255/18670	2.027e-07	3.301e-05	2.685e-05	CXCL13/EGR3/EBI3/IL1B/CD86/IL18/CD276/IL21/NR4A3/NLRP3/ICAM1/DUSP10/IL10/CD83/CD80/RAC1/PDCD1/PTPN6/BCL6/CBFB/SIRPA/TNFSF4/TFRC/LGALS9/ADAM19/HMGB1/TNF/IL2RA/BTN2A2/FOXP3/CTLA4/IL4R/SMAD7/DOCK8/CCR2/SRC/HLA-G/LILRB4/HAVCR2/CD74/PAK1/CD1D/GRAP2/RPS3/EFNB1/HLX/LGALS1/CCL2/PNP/PAK3/DNAJA3/HLA-DPA1/PTPRC/CYLD/CORO1A/HLA-E/CD47/AIF1/ITGA6/AP3D1/FLOT1/SART1/NOD2/LILRB2/IL12RB1/IRAK1/THY1/CD46/CD44/PIEZO1/CITED2/IL7R/HLA-DMB/TNFSF9/PDCD1LG2/IL7/CD3E/CCDC88B/CARD11/IL4/RIPK2/CD6/HLA-DPB1/TRAF6/VNN1/TNFSF11/TGFB1/CDC42/KIF26B/HAS2/JAK3/RARA/HHLA2/DENND6A/KLRK1/ZAP70/GATA3/PTAFR/BAD/FYN/PAK2/IL23A	102
BP	GO:0007159	leukocyte cell-cell adhesion	128/4749	337/18670	2.061e-07	3.301e-05	2.685e-05	EGR3/EBI3/IL1B/CD86/SDC4/IL18/CD276/IL21/NR4A3/NLRP3/WNK1/ICAM1/DUSP10/ADORA2A/IL10/CD83/KLF4/CD80/RAC1/PDCD1/PTPN6/BCL6/CBFB/SIRPA/TNFSF4/TFRC/LGALS3/GPNMB/CEACAM1/LGALS9/HMGB1/TNF/IL2RA/BTN2A2/TNFRSF21/FOXP3/ADTRP/CTLA4/IL4R/SMAD7/DOCK8/CCR2/SRC/HLA-G/LILRB4/TIGIT/HAVCR2/CD74/PAK1/CD177/CD1D/GRAP2/RPS3/EFNB1/CLEC4G/HLX/LGALS1/CCL2/PNP/PAK3/DNAJA3/HLA-DPA1/PTPRC/EZR/CYLD/CORO1A/HLA-E/CD47/AIF1/DUSP22/AP3D1/SART1/FERMT3/NOD2/LILRB2/IL12RB1/IRAK1/THY1/ARG1/LAG3/CD46/ERBB2/CD44/RAC2/CEBPB/IL7R/IDO1/DTX1/HLA-DMB/TNFSF9/PDCD1LG2/ZC3H12A/NRARP/IL7/CD3E/DLG5/CCDC88B/CARD11/S100A8/IL4/PRNP/RIPK2/UMOD/CD6/NT5E/SEMA4D/HLA-DPB1/TRAF6/VNN1/TNFSF11/TGFB1/CDC42/HAS2/GLMN/JAK3/RARA/HHLA2/KLRK1/ZAP70/GATA3/PTAFR/ADD2/CX3CR1/LRRC32/BAD/FYN/PAK2/IL23A	128
BP	GO:0008637	apoptotic mitochondrial changes	58/4749	124/18670	2.163e-07	3.379e-05	2.749e-05	PPIF/TP73/BNIP3L/PLAUR/MLLT11/YWHAH/PRELID1/MMP9/YWHAE/TP63/YWHAZ/E2F1/HK2/HSPA1A/NOL3/BAX/PMAIP1/NAIF1/GPX1/LMNA/FXN/IFI6/MOAP1/SFN/ATP2A1/PIM2/BMF/CLU/CAMK2A/HIP1R/PDCD5/BIK/EYA2/CCK/NMT1/BID/PINK1/TIMM50/TFDP2/NDUFS1/BAK1/YWHAQ/JUN/SLC25A5/STPG1/ZNF205/BCL2L1/GSK3A/CIDEB/TNFSF10/RHOT2/FZD9/GCLC/PAM16/IFIT2/SLC25A4/PSMD10/BAD	58
BP	GO:0006261	DNA-dependent DNA replication	68/4749	153/18670	2.361e-07	3.601e-05	2.93e-05	E2F7/E2F8/TICRR/CDT1/BCL6/MCM4/MCM5/CDC6/GMNN/MCM10/SMC3/MSH6/RRM2B/BRCA2/CDK2AP1/FEN1/RAD51/MCM2/FBXO5/DBF4/TONSL/DBF4B/CDC45/GINS2/CDK2/GINS1/ORC1/POLQ/RFWD3/GINS4/CCNE2/ZRANB3/UPF1/RFC2/MCM7/TERF1/DNAJA3/DSCC1/POLD4/TIMELESS/RECQL5/CHTF8/AICDA/RNASEH2A/POLE/MCM3/RECQL4/SAMHD1/ZNF830/EME1/DDX11/DNA2/ETAA1/POLG2/SSBP1/HELB/CHEK2/POLN/SMC1A/NUCKS1/WIZ/WRN/ATG7/ORC2/LRWD1/TIPIN/POLE2/TERF2	68
BP	GO:0071346	cellular response to interferon-gamma	77/4749	180/18670	2.688e-07	4.004e-05	3.257e-05	CDC42EP4/IRF7/PPARG/ICAM1/CCL20/CCL3L3/HCK/FCGR1B/IRF4/GAPDH/MRC1/ZYX/SIRPA/CCL22/OAS2/GBP2/LGALS9/PML/IFI30/IRF5/GSN/TLR4/HLA-DQB2/TRIM25/MT2A/TRIM26/ACTG1/PARP14/FCGR1A/HLA-H/SOCS3/HLA-G/TRIM62/CCL3/CAMK2A/OASL/CCL2/TRIM22/CCL17/HLA-DPA1/PIAS1/HLA-E/CD47/AIF1/ADAMTS13/CCL18/TLR2/HLA-DRA/CD58/IL12RB1/TXK/MID1/SLC26A6/ARG1/SUMO1/CD44/CAMK2G/VAMP3/IRF3/VIM/HLA-DQA2/OAS1/DAPK1/IFNGR1/CAMK2D/HLA-DPB1/CCL23/STAT1/CCL7/GBP4/CCL15/WAS/HLA-DRB1/PTAFR/RAB12/JAK1/TRIM5	77
BP	GO:0000281	mitotic cytokinesis	39/4749	73/18670	2.946e-07	4.289e-05	3.489e-05	KIF20A/ESPL1/CENPA/ANLN/KIF4A/CDT1/KIF23/CIT/CEP55/KIF20B/NUSAP1/RACGAP1/RTKN/STAMBP/SNX9/CHMP2B/MYH10/INCENP/BRCA2/PLK1/CKAP2/KIF4B/UNC119/SPTBN1/STMN1/CFL1/ECT2/SNX33/CHMP1A/CHMP2A/TTC19/APC/MAP9/EFHC1/ARL3/MITD1/NUP62/CHMP3/KLHDC8B	39
BP	GO:0050863	regulation of T cell activation	120/4749	314/18670	3.356e-07	4.777e-05	3.886e-05	EGR3/EBI3/IL1B/CD86/SDC4/IL18/CD276/IL21/NLRP3/DUSP10/ADORA2A/IL10/CD83/CD80/RAC1/PDCD1/PTPN6/IRF4/BCL6/TNFRSF18/TREX1/CBFB/SIRPA/TNFSF4/TFRC/LGALS3/GPNMB/CEACAM1/PRELID1/LGALS9/PRDM1/HMGB1/GSN/IL2RA/BTN2A2/TNFRSF21/FOXP3/CTLA4/IL4R/SMAD7/DOCK8/RIPK3/CCR2/SRC/HLA-G/SIT1/LILRB4/TIGIT/HAVCR2/CD74/PAK1/KAT2A/CD1D/GRAP2/RPS3/EFNB1/CLEC4G/HLX/LGALS1/CCL2/PNP/PAK3/DNAJA3/HLA-DPA1/PTPRC/CYLD/CORO1A/HLA-E/CD47/AIF1/DUSP22/LAT/AP3D1/SART1/NOD2/LILRB2/IL12RB1/THY1/ARG1/LAG3/CD46/ERBB2/RAC2/CEBPB/IL7R/IDO1/DTX1/HLA-DMB/TNFSF9/PDCD1LG2/ZC3H12A/NRARP/IL7/CD3E/DLG5/CCDC88B/CARD11/IL4/PRNP/RIPK2/TNFRSF1B/CD6/HLA-DPB1/TRAF6/VNN1/TNFSF11/TGFB1/CDC42/GLMN/JAK3/RARA/HHLA2/KLRK1/ZAP70/GATA3/LRRC32/BAD/FYN/PAK2/IL23A	120
BP	GO:0002283	neutrophil activation involved in immune response	173/4749	488/18670	4.179e-07	5.819e-05	4.734e-05	QPCT/PLAC8/ANPEP/RAB31/ACPP/MVP/CD68/FPR1/RAC1/PTPN6/LRG1/SERPINB6/CTSH/CYSTM1/PLAUR/GRN/CPPED1/CYFIP1/OLR1/LAIR1/SIRPA/SURF4/CTSA/GLB1/CANT1/HPSE/TIMP2/LGALS3/PGAM1/CEACAM1/ATP11A/MMP9/BRI3/ATP8B4/GPI/HMGB1/GSN/GM2A/HSPA1A/NEU1/CYBB/PLAU/LILRA2/ANXA2/AGPAT2/CAPN1/ARHGAP9/SLC2A3/TUBB/ITGAX/FCN1/HLA-H/TMEM63A/P2RX1/RHOG/PKM/GGH/FABP5/ALDOC/PLEKHO2/VCP/TXNDC5/SLC27A2/SDCBP/CST3/BST2/LYZ/CD33/PSMD1/TUBB4B/PSMD2/CFD/TCN1/CD177/RAB3D/SNAP29/MAN2B1/XRCC6/CTSB/ATP6V0C/TBC1D10C/PNP/TOLLIP/PRG2/QSOX1/PTPRC/PIGR/NFAM1/CD47/FUCA2/PA2G4/TLR2/COTL1/SPTAN1/PRCP/TOM1/HVCN1/ARPC5/ALOX5/CD58/LILRB2/SNAP23/CTSD/PSMA5/TMEM30A/ARG1/FTL/RAB27A/EEF1A1/MNDA/FPR2/UNC13D/ENPP4/CLEC4D/PSMB7/C3AR1/S100A11/CD44/C6orf120/PTGES2/CTSZ/FTH1/FCAR/MPO/IST1/CYBA/APRT/RHOF/IMPDH1/HSPA6/CKAP4/PADI2/PRDX6/LAMP1/ALDOA/S100A8/SYNGR1/AMPD3/TNFRSF1B/GLIPR1/TYROBP/ALDH3B1/HBB/HMOX2/CLEC5A/CNN2/DEFA1B/LAMTOR2/AGA/HEXB/GUSB/DEFA4/BCR/RAB37/VNN1/MANBA/PFKL/PPBP/STOM/FUCA1/ATG7/PSMB1/PSMD7/NIT2/MAPK1/SLCO4C1/PTAFR/DSC1/ORMDL3/NME2/NHLRC3/CD93/PSMD11	173
BP	GO:0043312	neutrophil degranulation	172/4749	485/18670	4.388e-07	5.981e-05	4.866e-05	QPCT/PLAC8/ANPEP/RAB31/ACPP/MVP/CD68/FPR1/RAC1/PTPN6/LRG1/SERPINB6/CTSH/CYSTM1/PLAUR/GRN/CPPED1/CYFIP1/OLR1/LAIR1/SIRPA/SURF4/CTSA/GLB1/CANT1/HPSE/TIMP2/LGALS3/PGAM1/CEACAM1/ATP11A/MMP9/BRI3/ATP8B4/GPI/HMGB1/GSN/GM2A/HSPA1A/NEU1/CYBB/PLAU/ANXA2/AGPAT2/CAPN1/ARHGAP9/SLC2A3/TUBB/ITGAX/FCN1/HLA-H/TMEM63A/P2RX1/RHOG/PKM/GGH/FABP5/ALDOC/PLEKHO2/VCP/TXNDC5/SLC27A2/SDCBP/CST3/BST2/LYZ/CD33/PSMD1/TUBB4B/PSMD2/CFD/TCN1/CD177/RAB3D/SNAP29/MAN2B1/XRCC6/CTSB/ATP6V0C/TBC1D10C/PNP/TOLLIP/PRG2/QSOX1/PTPRC/PIGR/NFAM1/CD47/FUCA2/PA2G4/TLR2/COTL1/SPTAN1/PRCP/TOM1/HVCN1/ARPC5/ALOX5/CD58/LILRB2/SNAP23/CTSD/PSMA5/TMEM30A/ARG1/FTL/RAB27A/EEF1A1/MNDA/FPR2/UNC13D/ENPP4/CLEC4D/PSMB7/C3AR1/S100A11/CD44/C6orf120/PTGES2/CTSZ/FTH1/FCAR/MPO/IST1/CYBA/APRT/RHOF/IMPDH1/HSPA6/CKAP4/PADI2/PRDX6/LAMP1/ALDOA/S100A8/SYNGR1/AMPD3/TNFRSF1B/GLIPR1/TYROBP/ALDH3B1/HBB/HMOX2/CLEC5A/CNN2/DEFA1B/LAMTOR2/AGA/HEXB/GUSB/DEFA4/BCR/RAB37/VNN1/MANBA/PFKL/PPBP/STOM/FUCA1/ATG7/PSMB1/PSMD7/NIT2/MAPK1/SLCO4C1/PTAFR/DSC1/ORMDL3/NME2/NHLRC3/CD93/PSMD11	172
BP	GO:0000086	G2/M transition of mitotic cell cycle	98/4749	247/18670	5.434e-07	7.252e-05	5.9e-05	CENPF/AURKB/PKMYT1/TPX2/KIF14/FOXM1/TICRR/CDK1/CDKN1A/DTL/PHLDA1/AURKA/CIT/HSPA2/CDKN2B/MELK/NEK2/CCNA2/CLSPN/CCNB2/CDC25A/YWHAE/CDC6/PLK4/PPP2R1A/PPP1CB/ODF2/PLK1/CDC25C/CENPJ/WNT10B/TUBB/CCNB1/FGFR1OP/FBXO5/DBF4B/PSMD8/FBXL18/CDK2/PSMD1/TUBB4B/PSMD2/ORC1/TOPBP1/PSMF1/CDK14/CEP152/CDK7/CEP70/BRD4/SFI1/PSMD9/PSMA5/TAOK3/KDM8/PSMB7/TUBB4A/FBXW11/GPR132/CEP192/PSMD5/MIIP/ALMS1/ZNF830/PSME2/BRSK2/HAUS5/BTRC/PSMB5/ACTR1A/NAE1/TUBG1/MNAT1/CETN2/CHEK2/PSMB4/CEP72/PSMA3/CCNY/PPP1R12B/FBXL15/BACH1/PBX1/MTA3/ATM/PSMD10/PLCB1/PSMB1/PSMD7/PPP1R12A/PSMB3/CDC25B/CCND1/SYF2/PSMC5/CKAP5/NINL/PSMD11	98
BP	GO:0044839	cell cycle G2/M phase transition	104/4749	266/18670	5.703e-07	7.456e-05	6.066e-05	CENPF/AURKB/PKMYT1/TPX2/KIF14/GTSE1/FOXM1/TICRR/CDK1/CDKN1A/DTL/PHLDA1/AURKA/CIT/HSPA2/CDKN2B/MELK/NEK2/CCNA2/CLSPN/DYRK3/CCNB2/CDC25A/YWHAE/CDC6/PLK4/PPP2R1A/ATF5/PPP1CB/ODF2/PLK1/CDC25C/CENPJ/WNT10B/TUBB/CCNB1/FGFR1OP/FBXO5/DBF4B/PSMD8/FBXL18/CDK2/PSMD1/TUBB4B/PSMD2/ORC1/TOPBP1/PSMF1/CDK14/CEP152/CDK7/CEP70/BRD4/SFI1/PSMD9/PSMA5/TAOK3/KDM8/BRCC3/PSMB7/TUBB4A/FBXW11/CHEK1/GPR132/CEP192/PSMD5/MIIP/ALMS1/ZNF830/PSME2/BRSK2/HAUS5/BTRC/PSMB5/CDC14B/ACTR1A/NAE1/TUBG1/MNAT1/CETN2/CHEK2/PSMB4/CEP72/PSMA3/CCNY/PPP1R12B/FBXL15/BACH1/PBX1/MTA3/ATM/PSMD10/PLCB1/PSMB1/PSMD7/PPP1R12A/PSMB3/CDC25B/CCND1/SYF2/PSMC5/CKAP5/NINL/PSMD11	104
BP	GO:0043393	regulation of protein binding	88/4749	217/18670	6.767e-07	8.562e-05	6.965e-05	CRMP1/AURKB/AURKA/GPSM1/PTPRF/IL10/IFIT1/PHLDA2/TTBK1/TIRAP/CAMK1/CDK5/ANXA2P2/LGALS3/MMP9/SYAP1/HSPA5/PLK2/DERL1/BAX/PLK1/SPPL3/ANXA2/SORL1/SRC/BTBD1/DTX3L/TIAM1/CTHRC1/TMC8/ARRB1/PIM2/GREM2/PRMT7/HIP1R/TCF7L2/CARM1/CYLD/LRPAP1/STK3/STMN1/TFIP11/PLXND1/DVL1/FLOT1/VTN/PPP2CA/BAK1/TRAF4/FKBP1A/LRP1/PLCL2/DTNBP1/PARK7/EPB41L5/SPON1/STPG1/CRK/CTSZ/ADAM15/RAPGEF2/CCPG1/SNAPIN/BAG2/DDX11/TRAF2/CFHR1/ADIPOQ/RIPK2/LDLRAP1/EPB41/AIDA/CCL23/ARF6/IFIT2/RPL11/RALB/TNFSF11/MITD1/ID1/ADNP/DNAJB2/PDGFB/ZFPM1/CRBN/ADD2/TRIB3/ACTB	88
BP	GO:0042119	neutrophil activation	175/4749	498/18670	6.888e-07	8.562e-05	6.965e-05	QPCT/PLAC8/ANPEP/IL18/RAB31/ACPP/MVP/CD68/FPR1/RAC1/PTPN6/LRG1/SERPINB6/CTSH/CYSTM1/PLAUR/GRN/CPPED1/CYFIP1/OLR1/LAIR1/SIRPA/SURF4/CTSA/GLB1/CANT1/HPSE/TIMP2/LGALS3/PGAM1/CEACAM1/ATP11A/MMP9/BRI3/ATP8B4/GPI/HMGB1/GSN/GM2A/HSPA1A/NEU1/CYBB/PLAU/LILRA2/ANXA2/AGPAT2/CAPN1/ARHGAP9/SLC2A3/TUBB/ITGAX/FCN1/HLA-H/TMEM63A/P2RX1/RHOG/PKM/GGH/FABP5/ALDOC/PLEKHO2/VCP/TXNDC5/SLC27A2/SDCBP/CST3/BST2/LYZ/CD33/PSMD1/TUBB4B/PSMD2/CFD/TCN1/CD177/RAB3D/SNAP29/MAN2B1/XRCC6/CTSB/ATP6V0C/TBC1D10C/PNP/TOLLIP/PRG2/PREX1/QSOX1/PTPRC/PIGR/NFAM1/CD47/FUCA2/PA2G4/TLR2/COTL1/SPTAN1/PRCP/TOM1/HVCN1/ARPC5/ALOX5/CD58/LILRB2/SNAP23/CTSD/PSMA5/TMEM30A/ARG1/FTL/RAB27A/EEF1A1/MNDA/FPR2/UNC13D/ENPP4/CLEC4D/PSMB7/C3AR1/S100A11/CD44/C6orf120/PTGES2/CTSZ/FTH1/FCAR/MPO/IST1/CYBA/APRT/RHOF/IMPDH1/HSPA6/CKAP4/PADI2/PRDX6/LAMP1/ALDOA/S100A8/SYNGR1/AMPD3/TNFRSF1B/GLIPR1/TYROBP/ALDH3B1/HBB/HMOX2/CLEC5A/CNN2/DEFA1B/LAMTOR2/AGA/HEXB/GUSB/DEFA4/BCR/RAB37/VNN1/MANBA/PFKL/PPBP/STOM/FUCA1/ATG7/PSMB1/PSMD7/NIT2/MAPK1/SLCO4C1/PTAFR/DSC1/ORMDL3/NME2/NHLRC3/CD93/PSMD11	175
BP	GO:0060333	interferon-gamma-mediated signaling pathway	45/4749	91/18670	6.95e-07	8.562e-05	6.965e-05	IRF7/PPARG/ICAM1/HCK/FCGR1B/IRF4/OAS2/GBP2/PML/IFI30/IRF5/HLA-DQB2/TRIM25/MT2A/TRIM26/PARP14/FCGR1A/HLA-H/SOCS3/HLA-G/TRIM62/CAMK2A/OASL/TRIM22/HLA-DPA1/PIAS1/HLA-E/HLA-DRA/TXK/MID1/ARG1/SUMO1/CD44/CAMK2G/IRF3/HLA-DQA2/OAS1/IFNGR1/CAMK2D/HLA-DPB1/STAT1/HLA-DRB1/PTAFR/JAK1/TRIM5	45
BP	GO:0006612	protein targeting to membrane	83/4749	202/18670	7.316e-07	8.842e-05	7.193e-05	ZDHHC12/RPL3/CDK5/RPS8/HSPA5/RPL32/RPS25/RPS12/RPL10A/RPS18/RPS27/RPL35/RPL38/RPS10/RPS3A/RPLP2/RPL21/RPL19/RPL23A/RPS5/RPL36/RPL5/RPL4/RPL30/RPL27A/RPL26/RPS23/RPS6/RPS15/SDCBP/RPL36A/SEC61A2/RPL7/PAK1/RPL18A/RPS13/RPS20/RPL6/RPS3/RPS15A/RPS27A/MICALL1/SGTA/RPL23/RPS11/RPS19/PRKCI/UBA52/TRAM2/RPS16/ZDHHC24/RPS9/SEC61B/RPL14/RPL37A/CHP1/RPL37/ERBB2/RPL29/ZDHHC3/RPS4X/RPL12/RABGEF1/RPSA/PEX3/PEX5/RPS28/PRNP/ZDHHC4/ZFAND2B/RPL7A/RPL39/ZDHHC9/ZDHHC2/ZDHHC7/RPL11/NCF1/STOM/GDI1/USP17L2/RPL22/SSR2/FYN	83
BP	GO:0031570	DNA integrity checkpoint	68/4749	157/18670	7.585e-07	8.999e-05	7.321e-05	GTSE1/E2F7/E2F8/TICRR/CDK1/CDT1/CDKN1A/DTL/TOP2A/AURKA/DOT1L/TREX1/CLSPN/ZNF385A/CDC6/PML/E2F1/PLK2/BAX/PLK1/CDC25C/GADD45A/PEA15/CCNB1/SFN/RPL26/TP53BP1/CDC45/CDK2/CRY1/ORC1/RFWD3/TOPBP1/FBXO31/CARM1/CNOT3/TIPRL/TIMELESS/TFDP2/MUC1/FEM1B/MDM4/TAOK3/BRCC3/WDR76/CHEK1/RBL2/ZNF830/EME1/PRPF19/CNOT7/MDC1/CDC5L/DNA2/ETAA1/GIGYF2/CDC14B/GML/NAE1/ATR/CHEK2/ATM/CUL4A/CCND1/SYF2/FBXO4/TIPIN/RAD9A	68
BP	GO:0002695	negative regulation of leukocyte activation	74/4749	175/18670	7.811e-07	9.098e-05	7.401e-05	CD86/SDC4/HMGB3/TYRO3/ADORA2A/IL10/TSPAN32/CD80/PTPN6/BCL6/GRN/CBFB/TNFSF4/LGALS3/GPNMB/CEACAM1/LGALS9/HMGB1/IL2RA/CD200/BTN2A2/TNFRSF21/FOXP3/LDLR/MILR1/CTLA4/IL4R/SMAD7/CCR2/HMOX1/MERTK/HLA-G/SAMSN1/BTK/TIGIT/HAVCR2/AXL/CD74/CLEC4G/HLX/PGLYRP3/PTPRC/CD300LF/DUSP22/MICA/LILRB2/SLA2/ARG1/LAG3/TNFRSF13B/CNR1/RHBDD3/MNDA/ERBB2/PIBF1/CEBPB/IDO1/DTX1/SOX11/PDCD1LG2/ZC3H12A/NRARP/RABGEF1/DLG5/SFRP1/PRNP/FER/TYROBP/BCR/ATM/TGFB1/GLMN/JAK3/LRRC32	74
BP	GO:0006260	DNA replication	106/4749	274/18670	8.101e-07	9.267e-05	7.539e-05	E2F7/E2F8/TICRR/CDK1/CDT1/RBBP8/DTL/TOP3A/EXO1/RAC1/CCNA2/ESCO2/BCL6/CHAF1A/MCM4/TREX1/CLSPN/MCM5/CDC6/CHAF1B/PPP2R1A/GMNN/MCM10/SMC3/MSH6/RRM2B/NUP98/BRCA2/NASP/CDK2AP1/FEN1/RAD51/ING5/MCM2/RMI2/HCRT/FBXO5/DBF4/TONSL/TNFAIP1/DBF4B/CDC45/PIF1/GINS2/RRM1/CDK2/GINS1/ORC1/POLQ/RFWD3/GINS4/TOPBP1/CCNE2/NFIX/ZRANB3/UPF1/RFC2/MCM7/TERF1/DNAJA3/DSCC1/POLD4/TIMELESS/PPP2CA/RECQL5/CTC1/CHTF8/AICDA/RNASEH2A/JUN/POLE/MCM3/NFIA/S100A11/CHEK1/RECQL4/SAMHD1/MAP2K4/ZNF830/EME1/RRM2/DDX11/DNA2/ETAA1/POLG2/SSBP1/KCTD13/HELB/ATR/CHEK2/POLN/SMC1A/ATM/NUCKS1/ANKRD17/WIZ/WRN/ATG7/ORC2/LRWD1/CINP/TIPIN/BARD1/POLE2/TERF2/RAD9A	106
BP	GO:0002706	regulation of lymphocyte mediated immunity	65/4749	149/18670	9.7e-07	0.000109	8.869e-05	IL1B/CD1E/IL18/IL21/NLRP3/IL10/IL1R1/PTPN6/BCL6/TNFSF4/TFRC/CEACAM1/LGALS9/ULBP2/HMGB1/TNF/CD1A/FOXP3/RAET1E/CD1C/RSAD2/SMAD7/RIPK3/CCR2/HLA-H/HLA-G/TP53BP1/SH2D1A/BTK/CD1B/HAVCR2/CD1D/CLEC4G/PTPRC/TRPM4/HLA-E/DUSP22/SUPT6H/MICA/IL12RB1/IL27RA/ARG1/LAG3/CADM1/LTA/IL18R1/CRK/IL7R/APLF/TRAF2/LAMP1/TNFSF13/IL4/TNFRSF1B/ULBP1/MAD2L2/TRAF6/FZD5/TGFB1/WAS/KLRK1/CD96/GATA3/P2RX7/IL23A	65
BP	GO:2001235	positive regulation of apoptotic signaling pathway	75/4749	179/18670	1.011e-06	0.0001111	9.035e-05	G0S2/PPIF/SKIL/TP73/ADORA2A/CTSH/PLAUR/MLLT11/YWHAH/MCL1/MMP9/YWHAE/TP63/LGALS9/SFPQ/ATF3/PPP2R1A/PML/YWHAZ/SERINC3/TNFRSF12A/E2F1/GSN/BAX/PEA15/PMAIP1/TRAF7/PLAGL2/MSX1/ING5/RIPK3/MOAP1/SFN/RPL26/BMF/UBB/RPS3/HIP1R/PDCD5/BIK/NMT1/FAS/BID/PINK1/PTPRC/CYLD/BCAP31/STK3/TFDP2/BAK1/DDIT3/WWOX/STYXL1/YWHAQ/PARK7/TNFSF12/ZNF205/BCL2L1/CTNNA1/GSK3A/SFRP1/TRAF2/PIAS4/S100A8/ST18/CIDEB/TNFSF10/ITM2C/TIMP3/NUPR1/RPL11/BAD/PAK2/RAD9A/SIRT1	75
BP	GO:0001819	positive regulation of cytokine production	164/4749	464/18670	1.023e-06	0.0001111	9.035e-05	EGR1/EBI3/TWIST1/IL1B/MAPK11/FURIN/IRF7/CD86/IL18/CD276/CSF2/IL21/NR4A3/NLRP3/SULF2/CSF1R/IL10/IL1R1/CD83/CD80/IRF4/BCL3/TLR8/IL17A/GAPDH/HK1/IL1RN/TIRAP/TNFSF4/HPSE/CLEC7A/LGALS9/HMGB1/NFKB2/PQBP1/TNF/IRF5/SEMA7A/HSPA1A/CD200/TNFRSF8/CYBB/TLR4/LILRA2/SERPINE1/FOXP3/AGPAT2/MMP12/CARD9/STAT3/IL4R/RSAD2/FFAR2/FCN1/CCR2/SRC/HMOX1/SEC14L1/ARHGEF2/HLA-G/PDE4D/TIGIT/CCL3/CLU/PTGER4/IL12RB2/HAVCR2/PDE4B/CD74/ATF4/XRCC6/RPS3/FFAR3/LY9/NPLOC4/POLR3H/HLA-DPA1/SPTBN1/PTPRC/NFAM1/HLA-E/AIF1/TLR2/FLOT1/CD58/NOD2/LILRB2/IL12RB1/TXK/LRP1/IRAK1/IL27RA/DDIT3/IL26/OSM/CADM1/LTA/DHX33/IL18R1/C1QTNF3/TLR6/CD46/MNDA/PARK7/C3AR1/IL17RC/PIBF1/CEBPB/IDO1/CYBA/IRF3/PAEP/IL7/LILRA5/BIRC3/CD3E/FLT4/IL13/IFI16/CCDC88B/TRAF2/CARD11/IFNGR1/EIF2AK3/ADIPOQ/IL4/CD34/RIPK2/DDX41/F2R/MAPKAPK2/TYROBP/CD6/IL36A/CLEC5A/C1QBP/HLA-DPB1/AKIRIN2/TRAF6/CRCP/TSPAN6/STAT1/CARD8/POLR3GL/FZD5/DDT/ANKRD17/PLCB1/TGFB1/GLMN/TMF1/ZCCHC3/RARA/HHLA2/KLRK1/TRIM16/ZFPM1/GATA3/PTAFR/USP17L2/P2RX7/IL37/TRIM15/IL23A	164
BP	GO:0002456	T cell mediated immunity	50/4749	106/18670	1.059e-06	0.000113	9.197e-05	IL1B/CD1E/IL18/NLRP3/ICAM1/IL1R1/CTSH/TREX1/TNFSF4/CEACAM1/ULBP2/HMGB1/CD1A/FOXP3/RAET1E/CD1C/RSAD2/SMAD7/RIPK3/CCR2/HLA-H/HLA-G/CD1B/HPRT1/CD1D/CLEC4G/JAG1/PTPRC/TRPM4/HLA-E/RFTN1/DUSP22/MICA/IL12RB1/ARG1/IL18R1/RAB27A/CD46/IL7R/TRAF2/IL4/BTN3A2/TNFRSF1B/ULBP1/TRAF6/FZD5/WAS/GATA3/P2RX7/IL23A	50
BP	GO:0002703	regulation of leukocyte mediated immunity	82/4749	201/18670	1.202e-06	0.0001262	0.0001027	IL1B/CD1E/IL18/IL21/NLRP3/IL10/IL1R1/FES/PTPN6/BCL6/TNFSF4/TFRC/CEACAM1/LGALS9/ULBP2/HMGB1/TNF/CD1A/TLR4/FOXP3/GAB2/RAET1E/CD1C/IL4R/RSAD2/SMAD7/RIPK3/CCR2/HLA-H/HMOX1/HLA-G/TP53BP1/SH2D1A/BTK/CD1B/BST2/HAVCR2/CD177/CD1D/CLEC4G/PTPRC/TRPM4/HLA-E/DUSP22/SUPT6H/MICA/NOD2/IL12RB1/IL27RA/ARG1/LAG3/CADM1/LTA/IL18R1/UNC13D/CRK/RAC2/IL7R/APLF/RABGEF1/IL13/TRAF2/LAMP1/TNFSF13/IL4/TNFRSF1B/ULBP1/FER/MAD2L2/TRAF6/SPHK2/BCR/FZD5/TGFB1/WAS/JAK3/KLRK1/CD96/GATA3/PTAFR/P2RX7/IL23A	82
BP	GO:2001233	regulation of apoptotic signaling pathway	146/4749	406/18670	1.311e-06	0.0001354	0.0001102	G0S2/PPIF/SKIL/IL1B/TP73/CSF2/SGMS1/ICAM1/ADORA2A/FAIM2/CTSH/PLAUR/ZNF385A/MLLT11/RFFL/YWHAH/DAPK2/MCL1/ENO1/DNAJA1/LGALS3/PRELID1/MMP9/YWHAE/TP63/LGALS9/SFPQ/ATF3/PPP2R1A/PML/YWHAZ/SERINC3/TNFRSF12A/TNF/E2F1/GSN/HSPA1A/RRM2B/CTTN/NOL3/BAX/PTPN1/SERPINE1/PEA15/PMAIP1/GPX1/TRAF7/PLAGL2/LMNA/SYVN1/MSX1/ING5/RIPK3/FXN/SRC/IFI6/MOAP1/SNAI1/HMOX1/ARHGEF2/SFN/TMC8/RPL26/CFLAR/BMF/CLU/UBB/CD74/URI1/HERPUD1/RPS3/HTT/HIP1R/PDCD5/CTH/BIK/EYA2/NMT1/PHIP/FAS/TCF7L2/BID/TNFRSF10B/PINK1/PTPRC/CYLD/BCAP31/STRADB/STK3/ITGA6/FIGNL1/BCL2A1/TFDP2/TAF9B/MUC1/BAK1/MEIS3/FEM1B/DDIT3/BDKRB2/WWOX/GNAI2/STYXL1/YWHAQ/PARK7/BCL2L12/SLC25A5/CD44/TNFSF12/TRAF1/TXNDC12/DEPTOR/ZNF205/BCL2L1/YAP1/PTPMT1/IL7/SIAH2/CTNNA1/GSK3A/ASAH2/SFRP1/TRAF2/PIAS4/EIF2AK3/S100A8/ST18/CIDEB/TNFSF10/FZD9/GCLC/ITM2C/TIMP3/NUPR1/PAM16/RPL11/VNN1/PSMD10/NDUFA13/PDX1/CX3CR1/BAD/FYN/PAK2/RAD9A/SIRT1	146
BP	GO:0002446	neutrophil mediated immunity	173/4749	499/18670	2.082e-06	0.0002117	0.0001722	QPCT/PLAC8/ANPEP/RAB31/ACPP/MVP/CD68/FPR1/RAC1/PTPN6/LRG1/SERPINB6/CTSH/CYSTM1/PLAUR/GRN/CPPED1/CYFIP1/OLR1/LAIR1/SIRPA/SURF4/CTSA/GLB1/CANT1/HPSE/TIMP2/LGALS3/PGAM1/CEACAM1/ATP11A/MMP9/BRI3/ATP8B4/GPI/HMGB1/GSN/GM2A/HSPA1A/NEU1/CYBB/PLAU/ANXA2/AGPAT2/CAPN1/ARHGAP9/SLC2A3/TUBB/ITGAX/FCN1/HLA-H/TMEM63A/P2RX1/RHOG/PKM/GGH/FABP5/ALDOC/PLEKHO2/VCP/TXNDC5/SLC27A2/SDCBP/CST3/BST2/LYZ/CD33/PSMD1/TUBB4B/PSMD2/CFD/TCN1/CD177/RAB3D/SNAP29/MAN2B1/XRCC6/CTSB/ATP6V0C/TBC1D10C/PNP/TOLLIP/PRG2/QSOX1/PTPRC/PIGR/NFAM1/CD47/FUCA2/PA2G4/TLR2/COTL1/SPTAN1/PRCP/TOM1/HVCN1/ARPC5/ALOX5/CD58/LILRB2/SNAP23/CTSD/PSMA5/TMEM30A/ARG1/FTL/RAB27A/EEF1A1/MNDA/FPR2/UNC13D/ENPP4/CLEC4D/PSMB7/C3AR1/S100A11/CD44/C6orf120/PTGES2/CTSZ/FTH1/FCAR/WDR1/MPO/IST1/CYBA/APRT/RHOF/IMPDH1/HSPA6/CKAP4/PADI2/PRDX6/LAMP1/ALDOA/S100A8/SYNGR1/AMPD3/TNFRSF1B/GLIPR1/TYROBP/ALDH3B1/HBB/HMOX2/CLEC5A/CNN2/DEFA1B/LAMTOR2/AGA/HEXB/GUSB/DEFA4/BCR/RAB37/VNN1/MANBA/PFKL/PPBP/STOM/FUCA1/ATG7/PSMB1/PSMD7/NIT2/MAPK1/SLCO4C1/PTAFR/DSC1/ORMDL3/NME2/NHLRC3/CD93/PSMD11	173
BP	GO:0009132	nucleoside diphosphate metabolic process	67/4749	158/18670	2.258e-06	0.0002261	0.0001839	TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/GPI/CBFA2T3/SIRT6/HK2/NUP98/TJP2/ENTPD5/CMPK2/STAT3/DTYMK/NUDT16/PGM2L1/PKM/AK5/ALDOC/OGDH/HTR2A/PFKFB4/ENTPD2/NUP153/AK3/NME4/DDIT4/GALK1/PFKFB2/NUP88/ENO3/PRKAG2/NME3/POM121C/AK4/NUP205/RAE1/NUP50/ENTPD4/LRGUK/CARD11/ALDOA/GUK1/AMPD3/AK1/CMPK1/INSR/NUPR1/NUP93/PFKL/ALDOB/NUP35/NME9/AAAS/AK2/NUP62/P2RX7/SEH1L/NCOR1/BAD/NME2	67
BP	GO:0045785	positive regulation of cell adhesion	144/4749	403/18670	2.317e-06	0.0002284	0.0001858	CXCL13/EGR3/EBI3/IL1B/VEGFA/CD86/SDC4/IL18/CD276/IL21/NR4A3/ITGA2/NLRP3/ICAM1/DUSP10/ITGA3/NEDD9/IL10/CD83/CD80/RAC1/PDCD1/PTPN6/BCL6/TNFRSF18/CBFB/SIRPA/TNFSF4/TFRC/LGALS9/ADAM19/HMGB1/TNF/CSF1/IL2RA/BTN2A2/NINJ1/FOXP3/MYADM/BAG4/CTLA4/IL4R/SMAD7/DOCK8/CCR2/SRC/TGM2/TFE3/HLA-G/LILRB4/DOCK1/HAVCR2/CD74/PAK1/APBB1IP/LIMS1/CD1D/GRAP2/ZFHX3/RPS3/NID1/EFNB1/DOCK5/HLX/LGALS1/EMILIN2/CCL2/PNP/PAK3/PREX1/DNAJA3/HLA-DPA1/PTPRC/CYLD/PRKCA/CORO1A/HLA-E/CD47/AIF1/TRIOBP/PLEKHA2/ITGA6/AP3D1/FLOT1/VTN/S100A10/SART1/NOD2/LILRB2/IL12RB1/IRAK1/THY1/CD46/UNC13D/EPB41L5/ERBB2/CD44/CRK/PIEZO1/PRKCE/CITED2/IL7R/HLA-DMB/FRMD5/TNFSF9/PDCD1LG2/IL7/CD3E/CCDC88B/SFRP1/CARD11/IL4/RIPK2/CD6/UTRN/C1QBP/HLA-DPB1/TRAF6/TPM1/VNN1/TNFSF11/ARL2/ATM/TGFB1/CDC42/KIF26B/HAS2/JAK3/RARA/HHLA2/DENND6A/ADAM9/KLRK1/FMN1/ZAP70/LDB1/GATA3/PTAFR/BAD/FYN/PAK2/ILK/RAC3/IL23A	144
BP	GO:0019882	antigen processing and presentation	89/4749	226/18670	2.546e-06	0.0002467	0.0002007	KIF2C/CD1E/KIF4A/RELB/KIF15/ICAM1/KIF23/CD68/FCGR1B/SEC13/CTSH/TREX1/NCF4/RACGAP1/RAB33A/KIF18A/IFI30/SEC24D/CAPZB/CD1A/CYBB/HLA-DQB2/KIF11/HLA-DMA/CD1C/KLC1/FCGR1A/HLA-H/CENPE/CD207/HLA-G/PSMD8/RAB32/CD1B/KIF4B/PSMD1/PSMD2/CD74/CD1D/CTSF/PSMF1/DCTN5/HLA-DPA1/BCAP31/TAPBPL/HLA-E/RFTN1/HLA-DRA/AP3D1/AP1S1/NOD2/LILRB2/PSMD9/AP2S1/SNAP23/CTSD/PSMA5/LAG3/TAP1/RAB27A/CAPZA1/KIF3C/MR1/PSMB7/VAMP3/PSMD5/HLA-DMB/CYBA/HLA-DQA2/ERAP1/PSME2/PSMB5/ACTR1A/CANX/LNPEP/PSMB4/HLA-DPB1/TRAF6/PSMA3/RAB34/NCF1/PSMD10/PSMB1/WAS/PSMD7/PSMB3/HLA-DRB1/PSMC5/PSMD11	89
BP	GO:0000280	nuclear division	145/4749	407/18670	2.58e-06	0.0002467	0.0002007	ESPL1/CENPF/LIF/AURKB/PKMYT1/IL1B/KIF2C/CDCA8/TPX2/KIF14/ANLN/KIFC1/ASPM/CDCA5/KIF4A/UBE2C/BUB1B/NCAPG/TTK/MKI67/CDT1/TOP2A/BIRC5/ZWINT/AURKA/KIF23/HSPA2/KIF20B/NEK2/TRIP13/CDC20/PTTG1/DLGAP5/NUSAP1/BUB1/TACC3/MYBL2/SPAG5/RACGAP1/NCAPD2/KIF18A/CDC6/RAD54L/PPP2R1A/UBE2S/SMC3/CHMP2B/SYCE3/NUF2/INCENP/SLC2A8/FBXO43/HSPA1A/BRCA2/UBE2B/KIF11/PLK1/CDC25C/RAD51/PSRC1/MSX1/TDRD9/CKS2/CCNB1/CENPE/FBXO5/NUMA1/NDC80/KIF4B/DMC1/PDXP/UBB/MND1/MSTO1/BOD1/CCNE2/TERF1/PHIP/TOM1L2/TAF1L/DIS3L2/HELQ/CLASP2/DSCC1/FIGNL1/TUBG2/CHTF8/NCAPH/ANAPC11/REC8/CHEK1/USP44/PIBF1/CEP192/PRC1/PHF13/STAG3/RCC1/ANAPC1/XRCC3/EME1/KLHDC3/WRAP73/SYCE2/SIRT2/CHMP1A/CDC14B/NCAPH2/NSFL1C/TUBG1/UBR2/DMRTC2/MAD2L2/ASZ1/ANKRD31/CHEK2/CHMP2A/INSR/KLHL22/FGF8/APC/SMC1A/CHAMP1/MAP9/PPP1R9B/SIRT7/POGZ/ATM/AAAS/MLH3/SMC5/PHF23/PLCB1/TGFB1/TOM1L1/RNF212/CDC25B/CEP97/PDGFB/NUP62/SEH1L/KLHDC8B/CENPK/RAD54B/DUSP1	145
BP	GO:0002709	regulation of T cell mediated immunity	36/4749	70/18670	2.747e-06	0.0002588	0.0002105	IL1B/CD1E/IL18/NLRP3/IL1R1/TNFSF4/CEACAM1/HMGB1/CD1A/FOXP3/CD1C/RSAD2/SMAD7/RIPK3/CCR2/HLA-H/HLA-G/CD1B/CD1D/CLEC4G/PTPRC/TRPM4/HLA-E/DUSP22/IL12RB1/ARG1/IL18R1/IL7R/TRAF2/TNFRSF1B/TRAF6/FZD5/WAS/GATA3/P2RX7/IL23A	36
BP	GO:0000910	cytokinesis	71/4749	171/18670	2.875e-06	0.0002669	0.0002171	KIF20A/ESPL1/AURKB/CENPA/KIF14/ANLN/E2F7/E2F8/KIF4A/CDT1/AURKA/KIF23/CIT/CEP55/KIF20B/NUSAP1/RACGAP1/CDC6/RTKN/STAMBP/SNX9/CHMP2B/MYH10/INCENP/PLK2/BRCA2/SVIL/PLK1/CKAP2/FSD1/KIF4B/PDXP/UNC119/KLHL9/SPTBN1/STMN1/CFL1/PKP4/KLHL21/RAB11FIP3/PRKCE/ECT2/PRC1/SNX33/BCL2L1/IST1/UVRAG/PIK3C3/CHMP1A/CDC14B/MYH9/RAB11FIP4/CETN2/CENPV/CHMP2A/PIK3R4/TTC19/APC/MAP9/EFHC1/ARL3/MITD1/ALKBH4/CDC42/CDC25B/CXCR5/NUP62/CHMP3/KLHL13/TAS2R13/KLHDC8B	71
BP	GO:0098813	nuclear chromosome segregation	100/4749	262/18670	3.299e-06	0.0003019	0.0002456	ESPL1/CENPF/AURKB/KIF2C/CDCA8/KIF14/KIFC1/CDCA5/KIF4A/BUB1B/FAM83D/NCAPG/GEM/TTK/CDT1/TOP2A/ZWINT/KIF23/NEK2/TRIP13/CDC20/PTTG1/DLGAP5/ESCO2/NUSAP1/BUB1/TACC3/SPAG5/RACGAP1/NCAPD2/KIF18A/SFPQ/CDC6/PPP2R1A/SMC3/CHMP2B/SYCE3/NUF2/INCENP/UBE2B/PLK1/FEN1/PSRC1/CCNB1/RMI2/CENPE/FBXO5/NUMA1/NDC80/KIF4B/DMC1/MSTO1/BOD1/CCNE2/TERF1/DIS3L2/HELQ/DSCC1/TUBG2/CHTF8/TTL/NCAPH/ANAPC11/REC8/USP44/PIBF1/ECT2/PRC1/PHF13/STAG3/ANAPC1/XRCC3/EME1/DDX11/SYCE2/SIRT2/CHMP1A/NCAPH2/TUBG1/MAD2L2/ANKRD31/CHMP2A/KLHL22/APC/SMC1A/CHAMP1/AXIN2/POGZ/ATM/MLH3/SMC5/PHF23/CDC42/RNF212/TRAPPC12/NUP62/SEH1L/KLHDC8B/CENPK/DUSP1	100
BP	GO:0045787	positive regulation of cell cycle	139/4749	389/18670	3.442e-06	0.0003085	0.0002509	ESPL1/AURKB/IL1B/GPSM2/KIF14/GTSE1/E2F7/E2F8/CDCA5/UBE2C/TP73/FAM83D/CDK1/CDT1/CDKN1A/NR4A3/DTL/FOSL1/AURKA/KIF23/CIT/IL10/HSPA2/KIF20B/DLGAP5/NUSAP1/DYRK3/ZNF385A/SPAG5/RACGAP1/CDC25A/SFPQ/CDC6/PLK4/PML/ASCL1/EIF4EBP1/E2F1/PLK2/BRCA2/BAX/UBE2B/SVIL/CDC25C/GADD45A/CENPJ/ZBTB17/FEN1/WNT10B/PSRC1/MSX1/CKS2/CCNB1/NUDT16/SRC/FBXO5/DBF4/NUMA1/NDC80/SFN/RPL26/DBF4B/CDC45/CDK2/USP19/CKS1B/PKD2/ASNS/POC1A/RPS15A/PTK6/PHIP/CARM1/RPL23/PRKCA/CCNT2/AIF1/BRD4/TGM1/CNOT3/EZH2/CDK10/PKP4/TFDP2/MUC1/MDM4/TTL/ANAPC11/CHEK1/CCNK/RAD23A/PRKCE/MYBBP1A/CITED2/ECT2/C6orf89/RBL2/XRCC3/GDPD5/CNOT7/CCPG1/DDX11/SIRT2/CDC14B/RAB11FIP4/CRLF3/GML/NSFL1C/FZD9/MNAT1/LRP6/ANKRD31/CHEK2/CENPV/INSR/FGF8/RRP8/CCNY/PBX1/MTA3/UHRF2/ADAMTS1/ATM/ANKRD17/WIZ/PSMD10/SMC5/PLCB1/TGFB1/CDC42/CUL4A/POU4F1/CDC25B/RARA/CCND1/CXCR5/PDGFB/NUP62/TAS2R13	139
BP	GO:0007098	centrosome cycle	55/4749	124/18670	3.481e-06	0.0003085	0.0002509	CCNF/STIL/CDK1/AURKA/WDR62/FES/NEK2/SLC16A1/PLK4/SAC3D1/CHMP2B/ATF5/PLK2/BRCA2/ODF2/KIF11/PLK1/GADD45A/CENPJ/UXT/CDK2/KAT2A/PKD2/POC1A/NUBP1/MDM1/CEP152/TUBE1/CHORDC1/CHEK1/MARK4/CEP192/PARD6G/C10orf90/UVRAG/ALMS1/XRCC3/HAUS5/CHMP1A/NSFL1C/TMEM67/CETN2/PARD6B/CHMP2A/CEP72/MAP9/PARD6A/ARL2/CETN3/MCPH1/PPP1R12A/SYNE2/NUP62/CHMP3/CKAP5	55
BP	GO:0032649	regulation of interferon-gamma production	47/4749	101/18670	3.531e-06	0.0003085	0.0002509	EBI3/IL1B/IL18/CD276/IL21/IL10/IL1R1/ISG15/BCL3/TLR8/SIRPA/TNFSF4/CLEC7A/LGALS9/HMGB1/TNF/TLR4/FOXP3/RIPK3/CCR2/PDE4D/IL12RB2/HAVCR2/PDE4B/AXL/PGLYRP3/HLA-DPA1/CD47/IL12RB1/TXK/IL27RA/LTA/IL18R1/PDCD1LG2/ZC3H12A/CD3E/PRNP/RIPK2/C1QBP/HLA-DPB1/FZD5/RARA/KLRK1/CD96/ZFPM1/GATA3/IL23A	47
BP	GO:0030098	lymphocyte differentiation	128/4749	353/18670	3.563e-06	0.0003085	0.0002509	EGR1/EGR3/CD86/IL18/JAG2/RELB/HMGB3/TYRO3/NLRP3/DUSP10/IL10/BATF/CD83/NTRK1/SRF/CD80/PTPN6/IRF4/BCL3/BCL6/TNFRSF18/SPI1/CBFB/TNFSF4/PRELID1/LGALS9/PRDM1/HMGB1/IL2RA/BAX/BTN2A2/MTOR/FOXP3/ITM2A/CMTM7/CTLA4/STAT3/IL4R/RSAD2/SMAD7/ITFG2/TOX/CCR6/RIPK3/CCR2/MERTK/HLA-G/LILRB4/RPS6/BTK/PTGER4/AXL/CD74/KAT2A/RBPJ/LYL1/CD1D/FLT3/LY9/HLX/RUNX2/LGALS1/PPP2R3C/SATB1/PNP/ZFP36L2/RORC/PREX1/DNAJA3/PGLYRP3/CD79B/PATZ1/PTPRC/CYLD/NFAM1/KLF6/AP3D1/SART1/BAK1/LILRB2/IL12RB1/AICDA/PLCL2/CD19/LAG3/IL18R1/CD46/FZD8/CLEC4D/CR2/ERBB2/IL7R/DTX1/TNFSF9/ZC3H12A/NRARP/IL7/ITK/POLM/CD3E/SFRP1/CARD11/IL4/NHEJ1/RIPK2/NCAPH2/PAX1/FZD9/ZFP36L1/HDAC9/VNN1/ATP11C/THEMIS/FZD5/DLL1/ATM/POU2F2/RAG2/TGFB1/JAK3/RARA/MIR17HG/ZAP70/ZFPM1/GATA3/RPL22/BAD/IL23A	128
BP	GO:0022407	regulation of cell-cell adhesion	143/4749	403/18670	3.867e-06	0.0003303	0.0002687	CXCL13/EGR3/EBI3/IL1B/VEGFA/CD86/SDC4/IL18/CD276/IL21/NR4A3/NLRP3/WNK1/ICAM1/DUSP10/ADORA2A/IL10/CD83/KLF4/CD80/RAC1/PDCD1/PTPN6/BCL6/IL1RN/CBFB/SIRPA/TNFSF4/TFRC/LGALS3/GPNMB/CEACAM1/LGALS9/CD9/ADAM19/NF2/HMGB1/TNF/IL2RA/BTN2A2/TNFRSF21/FOXP3/ADTRP/MYADM/CTLA4/IL4R/SMAD7/DOCK8/SWAP70/CCR2/SRC/ABAT/HLA-G/LILRB4/TIGIT/HAVCR2/CD74/PAK1/CD1D/GRAP2/RPS3/EFNB1/CLEC4G/HLX/LGALS1/CCL2/PNP/PAK3/JAG1/DNAJA3/HLA-DPA1/PTPRC/CYLD/PRKCA/CORO1A/HLA-E/CD47/AIF1/ITGA6/DUSP22/AP3D1/FLOT1/SART1/FERMT3/NOD2/LILRB2/IL12RB1/IRAK1/THY1/ARG1/LAG3/CD46/EPB41L5/ERBB2/CD44/FXYD5/PIEZO1/CITED2/CEBPB/IL7R/IDO1/DTX1/HLA-DMB/TNFSF9/PDCD1LG2/ZC3H12A/MINK1/NRARP/ZNF703/IL7/CD3E/DLG5/CCDC88B/CARD11/MDGA1/ADIPOQ/IL4/PRNP/RIPK2/CD6/MAD2L2/HLA-DPB1/TRAF6/VNN1/TNFSF11/TGFB1/CDC42/KIF26B/HAS2/GLMN/JAK3/RARA/HHLA2/DENND6A/KLRK1/ZAP70/GATA3/PTAFR/LRRC32/BAD/FYN/PAK2/IL23A	143
BP	GO:0010948	negative regulation of cell cycle process	130/4749	361/18670	4.498e-06	0.0003792	0.0003085	ESPL1/CENPF/LIF/AURKB/CCNF/GTSE1/E2F7/E2F8/BUB1B/TTK/TICRR/CDK1/CDT1/RBBP8/CDKN1A/DTL/AURKA/KANK2/CDKN2B/KLF4/NEK2/TRIP13/CDC20/PTTG1/BCL6/CLSPN/BUB1/ZNF385A/GPNMB/CDC6/PML/SMC3/ATF5/E2F1/MSH6/FBXO43/PLK2/BAX/BTN2A2/PLK1/CDC25C/CDKN2C/GADD45A/UXT/RAD51/RYBP/CCNB1/CBX5/FBXO5/NDC80/SFN/RPL26/HLA-G/PSMD8/CDK2/PSMD1/PSMD2/ORC1/RFWD3/KAT2A/CDK2AP2/PKD2/TOPBP1/PSMF1/NUBP1/CCL2/MDM1/ZFP36L2/TERF1/FBXO31/CARM1/TOM1L2/RPL23/PHC3/EED/CNOT3/EZH2/TFDP2/MUC1/CDKN2A/PSMD9/PSMA5/MDM4/TAOK3/BRCC3/PCGF6/PSMB7/CHEK1/USP44/CCNK/GPR132/PSMD5/MIIP/RBL2/XRCC3/ZNF830/PSME2/CNOT7/RRM2/GIGYF2/PSMB5/CDC14B/GML/NAE1/FZD9/TMEM67/ZFP36L1/MAD2L2/CHEK2/PSMB4/CHMP2A/MAX/KLHL22/PSMA3/APC/SMC1A/ATM/PSMD10/TOM1L1/PSMB1/PSMD7/ZNF655/PSMB3/BMI1/CCND1/SYF2/PSMC5/TERF2/PSMD11/DUSP1	130
BP	GO:0000076	DNA replication checkpoint	13/4749	16/18670	4.615e-06	0.000384	0.0003124	TICRR/CDT1/CLSPN/CDC6/CDC45/ORC1/TOPBP1/TIMELESS/ZNF830/DNA2/NAE1/TIPIN/RAD9A	13
BP	GO:0009185	ribonucleoside diphosphate metabolic process	60/4749	140/18670	4.981e-06	0.0004091	0.0003328	TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/GPI/CBFA2T3/SIRT6/HK2/NUP98/TJP2/ENTPD5/STAT3/NUDT16/PGM2L1/PKM/AK5/ALDOC/OGDH/HTR2A/PFKFB4/ENTPD2/NUP153/AK3/DDIT4/GALK1/PFKFB2/NUP88/ENO3/PRKAG2/POM121C/AK4/NUP205/RAE1/NUP50/ENTPD4/LRGUK/CARD11/ALDOA/GUK1/AMPD3/AK1/INSR/NUPR1/NUP93/PFKL/ALDOB/NUP35/AAAS/AK2/NUP62/P2RX7/SEH1L/NCOR1/BAD	60
BP	GO:0045621	positive regulation of lymphocyte differentiation	44/4749	94/18670	5.907e-06	0.000479	0.0003897	EGR3/CD86/IL18/NLRP3/DUSP10/CD83/CD80/BCL6/CBFB/TNFSF4/LGALS9/IL2RA/BTN2A2/FOXP3/IL4R/TOX/HLA-G/LILRB4/BTK/AXL/CD74/HLX/PPP2R3C/PNP/PTPRC/CYLD/AP3D1/SART1/LILRB2/IL12RB1/CD46/IL7R/TNFSF9/IL7/IL4/RIPK2/VNN1/ATP11C/TGFB1/RARA/ZAP70/GATA3/BAD/IL23A	44
BP	GO:0050866	negative regulation of cell activation	79/4749	199/18670	6.387e-06	0.000503	0.0004092	CD86/SDC4/HMGB3/TYRO3/ADORA2A/IL10/TSPAN32/PDGFA/CD80/PTPN6/BCL6/GRN/CBFB/TNFSF4/LGALS3/GPNMB/CEACAM1/LGALS9/CD9/HMGB1/IL2RA/CD200/BTN2A2/TNFRSF21/FOXP3/LDLR/MILR1/CTLA4/IL4R/SMAD7/CCR2/HMOX1/MERTK/ABAT/HLA-G/SAMSN1/BTK/TIGIT/HAVCR2/AXL/CD74/CLEC4G/HLX/PGLYRP3/PTPRC/CD300LF/DUSP22/MICA/LILRB2/SLA2/ARG1/LAG3/TNFRSF13B/CNR1/RHBDD3/MNDA/ERBB2/PIBF1/CEBPB/IDO1/DTX1/SOX11/PDCD1LG2/ZC3H12A/NRARP/RABGEF1/DLG5/SFRP1/PRNP/FER/TYROBP/GCLC/BCR/ATM/TGFB1/GLMN/JAK3/PDGFB/LRRC32	79
BP	GO:0042129	regulation of T cell proliferation	65/4749	156/18670	6.442e-06	0.000503	0.0004092	EBI3/IL1B/CD86/SDC4/IL18/CD276/IL21/IL10/CD80/PTPN6/TNFSF4/TFRC/LGALS3/GPNMB/LGALS9/HMGB1/IL2RA/BTN2A2/TNFRSF21/FOXP3/CTLA4/RIPK3/CCR2/HLA-G/HAVCR2/CD1D/RPS3/EFNB1/CLEC4G/PNP/DNAJA3/HLA-DPA1/PTPRC/CORO1A/HLA-E/AIF1/LILRB2/IL12RB1/ARG1/CD46/ERBB2/RAC2/CEBPB/IDO1/HLA-DMB/TNFSF9/PDCD1LG2/CD3E/DLG5/CCDC88B/CARD11/IL4/PRNP/RIPK2/TNFRSF1B/CD6/HLA-DPB1/TRAF6/TGFB1/GLMN/JAK3/HHLA2/ZAP70/LRRC32/IL23A	65
BP	GO:0009135	purine nucleoside diphosphate metabolic process	59/4749	138/18670	6.517e-06	0.000503	0.0004092	TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/GPI/CBFA2T3/SIRT6/HK2/NUP98/TJP2/ENTPD5/STAT3/NUDT16/PGM2L1/PKM/AK5/ALDOC/OGDH/HTR2A/PFKFB4/ENTPD2/NUP153/AK3/DDIT4/GALK1/PFKFB2/NUP88/ENO3/PRKAG2/POM121C/AK4/NUP205/RAE1/NUP50/LRGUK/CARD11/ALDOA/GUK1/AMPD3/AK1/INSR/NUPR1/NUP93/PFKL/ALDOB/NUP35/AAAS/AK2/NUP62/P2RX7/SEH1L/NCOR1/BAD	59
BP	GO:0009179	purine ribonucleoside diphosphate metabolic process	59/4749	138/18670	6.517e-06	0.000503	0.0004092	TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/GPI/CBFA2T3/SIRT6/HK2/NUP98/TJP2/ENTPD5/STAT3/NUDT16/PGM2L1/PKM/AK5/ALDOC/OGDH/HTR2A/PFKFB4/ENTPD2/NUP153/AK3/DDIT4/GALK1/PFKFB2/NUP88/ENO3/PRKAG2/POM121C/AK4/NUP205/RAE1/NUP50/LRGUK/CARD11/ALDOA/GUK1/AMPD3/AK1/INSR/NUPR1/NUP93/PFKL/ALDOB/NUP35/AAAS/AK2/NUP62/P2RX7/SEH1L/NCOR1/BAD	59
BP	GO:0032944	regulation of mononuclear cell proliferation	82/4749	209/18670	7.313e-06	0.0005577	0.0004537	EBI3/IL1B/CD86/SDC4/IL18/CD276/IL21/CDKN1A/IL10/CD80/PTPN6/BCL6/TIRAP/TNFSF4/TFRC/MZB1/LGALS3/GPNMB/LGALS9/HMGB1/CSF1/TNFRSF4/IL2RA/TLR4/BTN2A2/TNFRSF21/FOXP3/CTLA4/RIPK3/CCR2/HLA-G/BTK/HAVCR2/CD74/CD1D/RPS3/EFNB1/CLEC4G/PNP/DNAJA3/HLA-DPA1/PTPRC/CORO1A/HLA-E/AIF1/LILRB2/IL12RB1/ARG1/TNFRSF13B/CD46/MNDA/ERBB2/RAC2/CEBPB/IDO1/HLA-DMB/SOX11/TNFSF9/PDCD1LG2/IL7/CD3E/IL13/DLG5/CCDC88B/CARD11/IL4/PRNP/RIPK2/TNFRSF1B/TYROBP/CD6/HLA-DPB1/TRAF6/ATM/SLC39A10/TGFB1/GLMN/JAK3/HHLA2/ZAP70/LRRC32/IL23A	82
BP	GO:0019058	viral life cycle	119/4749	328/18670	7.491e-06	0.0005608	0.0004563	FURIN/NOTCH1/CD86/ANPEP/CDK1/TYRO3/ITGA2/ICAM1/TOP2A/SLC1A5/IFIT1/CD80/CXCR6/ISG15/SEC13/MRC1/HAVCR1/TFRC/ANXA2P2/LGALS9/APOBEC3H/PML/SMC3/CHMP2B/KPNA2/MX1/TNF/TNFRSF4/GSN/HSPA1A/NUP98/TRIM25/ANXA2/LDLR/TRIM26/SMARCB1/IFIT5/HYAL3/RSAD2/SNF8/FCN1/IFITM2/PPIH/TRIM62/VCP/SLC52A1/HTR2A/BST2/MORC2/UBB/AXL/CD74/OASL/NUP153/CCR5/CTSB/CLEC4G/LGALS1/CCL2/RPS27A/ISG20/SLC52A2/TBC1D20/LRRC15/UBA52/TRIM13/BANF1/IFITM3/NUP88/AICDA/IFITM1/CD46/MID2/FMR1/NFIA/CR2/KPNA3/CCNK/POM121C/RAD23A/NUP205/RAE1/ZNF639/IST1/NUP50/ZC3H12A/UVRAG/OAS1/CNOT7/RPSA/IFI16/LAMP1/CHMP1A/ILF3/EEA1/ZC3HAV1/LRSAM1/HTATSF1/CLEC5A/CHMP2A/STAU1/RAB1A/TRIM35/NUP93/CTBP1/PCSK5/NUP35/STOM/NUCKS1/AAAS/CDC42/SETDB1/NUP62/SEH1L/CHMP3/RAB1B/UBP1/TRIM15/TRIM5	119
BP	GO:0001836	release of cytochrome c from mitochondria	31/4749	59/18670	7.529e-06	0.0005608	0.0004563	PPIF/PLAUR/MLLT11/PRELID1/MMP9/NOL3/BAX/PMAIP1/GPX1/LMNA/FXN/IFI6/MOAP1/SFN/BMF/CLU/PDCD5/BIK/CCK/BID/PINK1/TIMM50/BAK1/JUN/BCL2L1/CIDEB/TNFSF10/FZD9/PAM16/PSMD10/BAD	31
BP	GO:0051056	regulation of small GTPase mediated signal transduction	122/4749	338/18670	7.683e-06	0.0005657	0.0004602	TIAM2/KIF14/NOTCH1/PLEKHG2/FOXM1/ARHGEF39/SQSTM1/SH2B2/ARHGAP23/ITGA3/SIPA1L1/TRIP10/KANK2/NTRK1/RAC1/ARHGEF40/BCL6/RACGAP1/TIMP2/SGSM3/DEPDC1B/STAMBP/CSF1/ARHGEF18/SRGAP2/FGD2/SIPA1L2/CDC42SE1/ARHGAP9/MCF2L2/CYTH2/SRC/PSD4/ARHGEF12/MAPRE2/ARHGEF5/TNFAIP1/RHOG/TIAM1/ARHGEF2/F2RL2/ARHGAP11A/MAPKAP1/ARRB1/ARHGAP31/ARHGAP11B/ARHGAP19/AMOT/ARHGAP35/STK19/RASGRF2/STMN3/STARD13/ARHGAP5/GPR35/PREX1/PLEKHG1/EPS8L2/VAV2/STMN1/ARHGAP4/RASA3/PLEKHG7/ABCA1/A2M/FLOT1/P2RY10/CCDC125/IQSEC1/ARAP1/RASGRP4/ARHGAP15/PSD3/RAPGEF1/SRGAP3/ARAP3/GBF1/RASA4/CRK/ARHGAP33/RAC2/ECT2/MYO9B/RHOF/RABGEF1/RASAL1/RHOV/CHN1/RHOU/CD2AP/RAP1GAP2/KCTD13/RALGPS1/F2R/LZTR1/OBSCN/RHOT2/CYTH1/CDC42SE2/ARF6/ARHGAP18/ARHGDIA/ARHGAP17/AKAP13/BCR/ARHGAP24/CHN2/ARHGAP1/MCF2L/ARHGAP32/CDC42/NET1/RTN4R/RALGAPA1/NUP62/IQSEC3/GDI1/SHC1/SPATA13/RALBP1/ARHGEF26/RAC3	122
BP	GO:0031023	microtubule organizing center organization	57/4749	133/18670	8.488e-06	0.0006115	0.0004975	CCNF/STIL/CDK1/AURKA/WDR62/FES/NEK2/SLC16A1/PLK4/SAC3D1/CHMP2B/ATF5/PLK2/BRCA2/ODF2/KIF11/PLK1/GADD45A/CENPJ/UXT/CDK2/KAT2A/PKD2/POC1A/NUBP1/MDM1/CEP152/CLASP2/TUBE1/CHORDC1/CHEK1/MARK4/CEP192/PARD6G/C10orf90/UVRAG/ALMS1/XRCC3/HAUS5/CHMP1A/NSFL1C/TMEM67/CETN2/PARD6B/CHMP2A/CEP72/MAP9/PARD6A/ARL2/CETN3/MCPH1/BCAS3/PPP1R12A/SYNE2/NUP62/CHMP3/CKAP5	57
BP	GO:0002699	positive regulation of immune effector process	84/4749	216/18670	8.496e-06	0.0006115	0.0004975	IL1B/CD86/CD1E/IL18/IL21/NR4A3/NLRP3/IL1R1/FES/CD80/HK1/TNFSF4/TFRC/MZB1/LGALS9/ULBP2/GPI/TNF/TNFRSF4/SEMA7A/CD1A/TLR4/FOXP3/GAB2/RAET1E/CD1C/IL4R/RSAD2/FFAR2/CCR2/HLA-H/HMOX1/HLA-G/TP53BP1/SH2D1A/BTK/CD1B/CD74/CD177/CD1D/FFAR3/HLX/PTPRC/RPS19/HLA-E/MICA/NOD2/IL12RB1/ARG1/LAG3/CADM1/LTA/IL18R1/CD46/RAPGEF1/UNC13D/RAC2/HLA-DMB/RABGEF1/IL13/TRAF2/LAMP1/TNFSF13/IL4/RIPK2/ULBP1/FER/MAD2L2/KLK5/TRAF6/SPHK2/C6/FZD5/ANKRD17/TGFB1/ZCCHC3/RARA/KLRK1/GATA3/PTAFR/USP17L2/P2RX7/TRIM15/IL23A	84
BP	GO:0033044	regulation of chromosome organization	123/4749	342/18670	8.616e-06	0.0006133	0.0004989	ESPL1/CENPF/TWIST1/LIF/AURKB/IL1B/VEGFA/CDCA5/BUB1B/TTK/MKI67/CDT1/TOP2A/NEK2/TRIP13/CDC20/PTTG1/DLGAP5/BCL6/SPI1/PHF19/BUB1/TACC3/SFPQ/CDC6/PML/ZNHIT1/SETD7/SIRT6/SKI/UBE2B/PLK1/SPTY2D1/SMG5/FOXP3/FEN1/SMARCB1/LMNA/NAP1L2/CCNB1/SRC/MCM2/RMI2/CENPE/FBXO5/NUMA1/IWS1/NDC80/ARRB1/CDC45/PIF1/MORC2/KAT2A/UBE2N/BCOR/UPF1/RNF40/CCT5/TERF1/ZNF304/PINK1/EED/BRD4/SUPT6H/TNKS2/MUC1/ACD/CTC1/AICDA/GNL3/ANAPC11/FMR1/ATAD2/MAP1S/CHEK1/USP44/GTF2H2/C6orf89/ANAPC1/POT1/XRCC3/XRCC1/MLLT6/PADI2/DDX11/YLPM1/CAMK2D/TAF7/KDM5A/DMRTC2/SMG6/MNAT1/TADA2A/MAD2L2/ATR/CENPV/KLHL22/SPHK2/CTBP1/APC/AXIN2/TINF2/SENP6/MCPH1/ATM/SMC5/KDM4C/TGFB1/ZNF451/TRAPPC12/MAPK1/PPHLN1/ASF1A/SETDB1/PHF8/GATA3/USP17L2/ERCC1/FBXO4/TERF2/CCT3/SIRT1/DUSP1	123
BP	GO:1903708	positive regulation of hemopoiesis	74/4749	185/18670	9.01e-06	0.0006343	0.000516	EGR3/LIF/CD86/IL18/NLRP3/DUSP10/TRIB1/FES/CD83/CD80/ISG15/BCL6/IL17A/CBFB/TNFSF4/CCR1/LGALS9/HMGB1/TNF/CSF1/HSPA1A/IL2RA/BTN2A2/FOXP3/STAT3/ZBTB46/IL4R/TOX/PPARGC1B/HLA-G/LILRB4/BTK/GNAS/AXL/CD74/HLX/PPP2R3C/PNP/JAG1/PTPRC/CYLD/PRKCA/AP3D1/SART1/LILRB2/IL12RB1/CD46/JUN/CA2/IL7R/TNFSF9/KLF10/IL7/IL20/IL4/RIPK2/TYROBP/ZFP36L1/TESC/TRAF6/STAT1/VNN1/ATP11C/TNFSF11/FOS/SLC9B2/TGFB1/TMEM64/POU4F1/RARA/ZAP70/GATA3/BAD/IL23A	74
BP	GO:0045672	positive regulation of osteoclast differentiation	17/4749	25/18670	9.326e-06	0.0006494	0.0005283	IL17A/CCR1/TNF/CSF1/PPARGC1B/GNAS/CA2/KLF10/IL20/TYROBP/TRAF6/TNFSF11/FOS/SLC9B2/TMEM64/POU4F1/IL23A	17
BP	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	47/4749	104/18670	9.457e-06	0.0006514	0.00053	SKIL/TP73/CDKN1A/CASP9/PHLDA3/BCL3/ZNF385A/MCL1/TP63/PML/TNF/E2F1/MSH6/CRIP1/BRCA2/BAX/MOAP1/SNAI1/HMOX1/SFN/RPL26/CLU/CD74/RPS3/BID/DDIT4/BCL2A1/TAF9B/MUC1/BAK1/BCL2L12/TOPORS/CD44/AEN/BCL2L1/IFI16/PIAS4/CIDEB/TNFRSF1B/CHEK2/NUPR1/XPA/ATM/SHISA5/BAD/RAD9A/SIRT1	47
BP	GO:0002573	myeloid leukocyte differentiation	80/4749	204/18670	9.59e-06	0.0006536	0.0005317	LIF/IRF7/CD109/VEGFA/RELB/CSF2/PPARG/CSF1R/BATF/TRIB1/FES/RASSF2/IRF4/IL17A/SPI1/TFRC/CCR1/ANXA2P2/CEACAM1/MMP9/UBD/CBFA2T3/TNF/CSF1/LRRK1/TLR4/PIAS3/MTOR/GAB2/ANXA2/ESRRA/SBNO2/ZBTB46/SRC/PPARGC1B/TFE3/LILRB4/GNAS/CCL3/CD74/PIR/RBPJ/FAM20C/PRKCA/TLR2/MT1G/JUN/TOB2/CA2/CEBPB/KLF10/IFI16/IL20/BGLAP/SFRP1/ADIPOQ/IL4/MYH9/TYROBP/DHRS2/ZFP36L1/TESC/FASN/TRAF6/TNFSF11/FOS/SLC9B2/ZNF675/TGFB1/TMEM64/CDC42/CUL4A/POU4F1/RARA/ZFPM1/GATA3/TCTA/NME2/IL23A/SIRT1	80
BP	GO:0001659	temperature homeostasis	70/4749	173/18670	9.8e-06	0.0006608	0.0005376	EGR1/G0S2/IL1B/VEGFA/NOTCH1/PLAC8/IL18/GADD45G/IRF4/PCTP/THRA/ACOT11/TNF/SIRT6/TLR4/ARRDC3/GPX1/WNT10B/STAT3/IL4R/CCR2/SCD/HCRT/PPARGC1B/TFE3/ABAT/FABP5/GNAS/HTR2A/IGF1R/RBPJ/ATF4/PER2/MAP2K6/ACSL1/PRDM16/FOXO1/PRKAB2/KSR2/TLE3/CNOT3/ADIPOR2/DRD1/ADIPOR1/PLCL2/DDIT3/IL18R1/CNR1/NTSR1/ACVR2B/TSHR/EPAS1/CEBPB/ARNTL/ALMS1/IL13/GHRL/IP6K1/ADIPOQ/IL4/BSCL2/PTH2R/LNPEP/APC/TNFSF11/ID1/PGAM5/OMA1/LPIN1/MC3R	70
BP	GO:0032609	interferon-gamma production	50/4749	113/18670	1.03e-05	0.0006874	0.0005593	EBI3/IL1B/IL18/CD276/IL21/IL10/IL1R1/ISG15/BCL3/TLR8/SIRPA/TNFSF4/CLEC7A/LGALS9/HMGB1/TNF/TLR4/FOXP3/RIPK3/CCR2/PDE4D/IL12RB2/HAVCR2/PDE4B/AXL/PGLYRP3/HLA-DPA1/CD47/IL12RB1/TXK/IL27RA/LTA/IL18R1/AZI2/PDCD1LG2/ZC3H12A/ITK/CD3E/BTN3A2/PRNP/RIPK2/C1QBP/HLA-DPB1/FZD5/RARA/KLRK1/CD96/ZFPM1/GATA3/IL23A	50
BP	GO:0051250	negative regulation of lymphocyte activation	61/4749	146/18670	1.103e-05	0.0007286	0.0005928	CD86/SDC4/HMGB3/TYRO3/ADORA2A/IL10/CD80/PTPN6/BCL6/CBFB/TNFSF4/LGALS3/GPNMB/CEACAM1/LGALS9/HMGB1/IL2RA/BTN2A2/TNFRSF21/FOXP3/CTLA4/IL4R/SMAD7/MERTK/HLA-G/SAMSN1/BTK/TIGIT/HAVCR2/AXL/CD74/CLEC4G/HLX/PGLYRP3/DUSP22/MICA/LILRB2/SLA2/ARG1/LAG3/TNFRSF13B/RHBDD3/MNDA/ERBB2/PIBF1/CEBPB/IDO1/DTX1/SOX11/PDCD1LG2/ZC3H12A/NRARP/DLG5/SFRP1/PRNP/TYROBP/ATM/TGFB1/GLMN/JAK3/LRRC32	61
BP	GO:0051438	regulation of ubiquitin-protein transferase activity	28/4749	52/18670	1.121e-05	0.0007296	0.0005935	UBE2C/CDC20/GORASP1/UBE2S/ARRDC3/PLK1/SMAD7/DTX3L/RPL5/FBXO5/UBE2N/RPL23/PINK1/ARRDC4/FEM1B/LIMK1/PARK7/TOPORS/USP44/DCUN1D4/BAG2/CDC14B/MAD2L2/RAB1A/RPL11/BMI1/TRIB3/MAGEA2B	28
BP	GO:0070507	regulation of microtubule cytoskeleton organization	74/4749	186/18670	1.128e-05	0.0007296	0.0005935	CCNF/GPSM2/TPX2/SKA1/STIL/MAP6/AURKA/FES/NEK2/RAC1/SKA3/TACC3/SPAG5/KIF18A/PLK4/SMC3/CHMP2B/ATF5/HSPA1A/PLK2/KIF11/PLK1/CENPJ/CKAP2/RANGRF/FSD1/PSRC1/MAPRE2/NUMA1/ARHGEF2/CLIP3/PAK1/KAT2A/CDK2AP2/POC1A/RPS3/NUBP1/STMN3/MDM1/TERF1/FGF13/CEP70/CYLD/STMN1/CLASP2/CHORDC1/MID1/TUBB4A/MAP1S/CHEK1/MARK4/RAE1/TRIM54/C10orf90/ALMS1/XRCC3/GSK3A/PHLDB1/CHMP1A/NSFL1C/TMEM67/CHMP2A/MAP1A/APC/SMC1A/MAP9/ARL2/SENP6/MCPH1/SLAIN2/CEP97/CDH5/NUP62/CHMP3	74
BP	GO:0050670	regulation of lymphocyte proliferation	81/4749	208/18670	1.149e-05	0.0007359	0.0005987	EBI3/IL1B/CD86/SDC4/IL18/CD276/IL21/CDKN1A/IL10/CD80/PTPN6/BCL6/TIRAP/TNFSF4/TFRC/MZB1/LGALS3/GPNMB/LGALS9/HMGB1/TNFRSF4/IL2RA/TLR4/BTN2A2/TNFRSF21/FOXP3/CTLA4/RIPK3/CCR2/HLA-G/BTK/HAVCR2/CD74/CD1D/RPS3/EFNB1/CLEC4G/PNP/DNAJA3/HLA-DPA1/PTPRC/CORO1A/HLA-E/AIF1/LILRB2/IL12RB1/ARG1/TNFRSF13B/CD46/MNDA/ERBB2/RAC2/CEBPB/IDO1/HLA-DMB/SOX11/TNFSF9/PDCD1LG2/IL7/CD3E/IL13/DLG5/CCDC88B/CARD11/IL4/PRNP/RIPK2/TNFRSF1B/TYROBP/CD6/HLA-DPB1/TRAF6/ATM/SLC39A10/TGFB1/GLMN/JAK3/HHLA2/ZAP70/LRRC32/IL23A	81
BP	GO:0090068	positive regulation of cell cycle process	109/4749	298/18670	1.177e-05	0.0007468	0.0006076	ESPL1/AURKB/IL1B/GPSM2/KIF14/GTSE1/E2F7/E2F8/CDCA5/UBE2C/TP73/FAM83D/CDK1/CDT1/CDKN1A/DTL/AURKA/KIF23/CIT/HSPA2/KIF20B/DLGAP5/NUSAP1/DYRK3/ZNF385A/SPAG5/RACGAP1/CDC25A/SFPQ/CDC6/PLK4/PML/E2F1/PLK2/BAX/UBE2B/SVIL/CDC25C/GADD45A/CENPJ/ZBTB17/FEN1/WNT10B/MSX1/CCNB1/NUDT16/FBXO5/DBF4/NUMA1/NDC80/SFN/RPL26/DBF4B/CDC45/CDK2/USP19/PKD2/POC1A/PHIP/CARM1/RPL23/AIF1/BRD4/CNOT3/EZH2/CDK10/PKP4/TFDP2/MUC1/MDM4/ANAPC11/PRKCE/MYBBP1A/ECT2/RBL2/XRCC3/CNOT7/DDX11/SIRT2/CDC14B/RAB11FIP4/CRLF3/GML/NSFL1C/ANKRD31/CHEK2/CENPV/INSR/FGF8/RRP8/PBX1/MTA3/UHRF2/ADAMTS1/ATM/ANKRD17/WIZ/SMC5/PLCB1/TGFB1/CDC42/CUL4A/POU4F1/CDC25B/CCND1/CXCR5/PDGFB/NUP62/TAS2R13	109
BP	GO:0030217	T cell differentiation	91/4749	240/18670	1.211e-05	0.0007605	0.0006187	EGR1/EGR3/CD86/IL18/JAG2/RELB/NLRP3/DUSP10/BATF/CD83/SRF/CD80/IRF4/BCL3/BCL6/TNFRSF18/CBFB/TNFSF4/PRELID1/LGALS9/PRDM1/HMGB1/IL2RA/BTN2A2/MTOR/FOXP3/CTLA4/STAT3/IL4R/RSAD2/SMAD7/CCR6/RIPK3/CCR2/HLA-G/LILRB4/RPS6/PTGER4/CD74/KAT2A/CD1D/LY9/HLX/RUNX2/SATB1/PNP/ZFP36L2/RORC/PREX1/DNAJA3/PATZ1/PTPRC/CYLD/AP3D1/SART1/LILRB2/IL12RB1/LAG3/IL18R1/CD46/FZD8/CLEC4D/ERBB2/IL7R/DTX1/TNFSF9/ZC3H12A/NRARP/IL7/ITK/CD3E/CARD11/IL4/NHEJ1/RIPK2/NCAPH2/PAX1/ZFP36L1/VNN1/THEMIS/FZD5/RAG2/TGFB1/JAK3/RARA/ZAP70/ZFPM1/GATA3/RPL22/BAD/IL23A	91
BP	GO:0007093	mitotic cell cycle checkpoint	67/4749	165/18670	1.31e-05	0.0008146	0.0006627	CENPF/AURKB/GTSE1/E2F7/E2F8/BUB1B/TTK/TICRR/CDK1/CDT1/CDKN1A/TOP2A/ZWINT/AURKA/CDKN2B/TRIP13/CDC20/CLSPN/BUB1/ZNF385A/CDC6/PML/E2F1/PLK2/BAX/PLK1/CDC25C/GADD45A/CCNB1/NDC80/SFN/RPL26/RPS6/CDK2/ORC1/RFWD3/TOPBP1/FBXO31/CARM1/CNOT3/TFDP2/MUC1/MDM4/TAOK3/USP44/RBL2/BCL2L1/XRCC3/ZNF830/EME1/CNOT7/MDC1/GIGYF2/GML/NAE1/MAD2L2/CHEK2/KLHL22/APC/ATM/TGFB1/CCND1/SYF2/USP17L2/TIPIN/RAD9A/DUSP1	67
BP	GO:0072395	signal transduction involved in cell cycle checkpoint	36/4749	74/18670	1.401e-05	0.0008631	0.0007022	GTSE1/E2F7/E2F8/CDK1/CDKN1A/DTL/AURKA/TREX1/ZNF385A/PML/E2F1/PLK2/BAX/PLK1/CDC25C/GADD45A/CCNB1/SFN/RPL26/CDK2/CARM1/CNOT3/TFDP2/MUC1/MDM4/BRCC3/CHEK1/SOX11/RBL2/PRPF19/CNOT7/CDC5L/CDC14B/GML/CHEK2/ATM	36
BP	GO:0042098	T cell proliferation	73/4749	184/18670	1.443e-05	0.0008804	0.0007162	EBI3/IL1B/CD86/SDC4/IL18/CD276/IL21/IL10/CD80/PTPN6/TNFSF4/TFRC/LGALS3/GPNMB/LGALS9/HMGB1/TNFRSF4/IL2RA/BAX/BTN2A2/TNFRSF21/FOXP3/CTLA4/DOCK8/RIPK3/CCR2/HLA-G/RPS6/HAVCR2/CD1D/RPS3/EFNB1/CLEC4G/SATB1/PNP/DNAJA3/HLA-DPA1/PTPRC/CORO1A/HLA-E/AIF1/LILRB2/IL12RB1/ARG1/CD46/ERBB2/RAC2/CD151/CEBPB/IDO1/HLA-DMB/TNFSF9/PDCD1LG2/CD3E/DLG5/CCDC88B/CARD11/IL4/PRNP/RIPK2/TNFRSF1B/CD6/HLA-DPB1/TRAF6/TGFB1/GLMN/JAK3/HHLA2/ZAP70/P2RX7/LRRC32/FYN/IL23A	73
BP	GO:0002285	lymphocyte activation involved in immune response	72/4749	181/18670	1.48e-05	0.0008943	0.0007276	CD86/IL18/RELB/NLRP3/ICAM1/IL10/BATF/EXO1/CD80/IRF4/BCL3/BCL6/TNFSF4/TFRC/LGALS3/CEACAM1/LGALS9/HMGB1/MSH6/TLR4/MTOR/FOXP3/ITM2A/CD1C/STAT3/IL4R/SMAD7/ITFG2/SWAP70/CCR6/TP53BP1/RPS6/PTGER4/HAVCR2/APBB1IP/LY9/HLX/LGALS1/CD180/RORC/PGLYRP3/PTPRC/CORO1A/SUPT6H/IL12RB1/AICDA/IL27RA/PLCL2/RNF8/CD19/IL18R1/RAB27A/CD46/UNC13D/CLEC4D/APLF/HLA-DMB/ZC3H12A/LAMP1/TNFSF13/IL4/RIPK2/MAD2L2/DLL1/TGFB1/JAK3/RARA/ZFPM1/GATA3/ERCC1/RNF168/IL23A	72
BP	GO:0045619	regulation of lymphocyte differentiation	68/4749	169/18670	1.622e-05	0.0009711	0.00079	EGR3/CD86/IL18/HMGB3/NLRP3/DUSP10/CD83/CD80/PTPN6/IRF4/BCL6/TNFRSF18/CBFB/TNFSF4/PRELID1/LGALS9/PRDM1/HMGB1/IL2RA/BTN2A2/FOXP3/CTLA4/IL4R/SMAD7/TOX/CCR2/HLA-G/LILRB4/BTK/AXL/CD74/KAT2A/HLX/PPP2R3C/PNP/ZFP36L2/PGLYRP3/PTPRC/CYLD/NFAM1/AP3D1/SART1/LILRB2/IL12RB1/LAG3/CD46/ERBB2/IL7R/DTX1/TNFSF9/ZC3H12A/NRARP/IL7/SFRP1/CARD11/IL4/RIPK2/ZFP36L1/VNN1/ATP11C/TGFB1/JAK3/RARA/MIR17HG/ZAP70/GATA3/BAD/IL23A	68
BP	GO:0045582	positive regulation of T cell differentiation	39/4749	83/18670	1.755e-05	0.00104	0.0008464	EGR3/CD86/IL18/NLRP3/DUSP10/CD83/CD80/BCL6/CBFB/TNFSF4/LGALS9/IL2RA/BTN2A2/FOXP3/IL4R/HLA-G/LILRB4/CD74/HLX/PNP/PTPRC/CYLD/AP3D1/SART1/LILRB2/IL12RB1/CD46/IL7R/TNFSF9/IL7/IL4/RIPK2/VNN1/TGFB1/RARA/ZAP70/GATA3/BAD/IL23A	39
BP	GO:0034404	nucleobase-containing small molecule biosynthetic process	86/4749	226/18670	1.77e-05	0.00104	0.0008464	TPI1/DCTPP1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/TYMP/ENO1/PGAM1/PFKP/PDE4A/GPI/CBFA2T3/SIRT6/DHODH/HK2/TK1/NUP98/ENTPD5/GPX1/ABCD1/CNP/STAT3/DTYMK/NUDT16/NUDT1/PGM2L1/PKM/PDE4D/ALDOC/VCP/OGDH/HTR2A/PDE4B/PFKFB4/HPRT1/ENTPD2/NUP153/PNP/NME4/UPRT/DDIT4/GALK1/PFKFB2/NUP88/ENO3/PRKAG2/NME3/MTAP/POM121C/NUP205/RAE1/NUDT17/NUP50/SAMHD1/APRT/IMPDH1/ENTPD4/NUDT3/ALDOA/GUK1/AMPD3/NT5E/PDE7B/CMPK1/CTPS2/UCK2/INSR/NUPR1/NUP93/NEIL1/PFKL/ALDOB/NUP35/NME9/OGG1/AAAS/NT5C2/NUP62/P2RX7/SEH1L/NCOR1/NME2/ASPDH	86
BP	GO:0019884	antigen processing and presentation of exogenous antigen	72/4749	182/18670	1.845e-05	0.001075	0.0008743	KIF2C/CD1E/KIF4A/KIF15/KIF23/FCGR1B/SEC13/NCF4/RACGAP1/KIF18A/IFI30/SEC24D/CAPZB/CD1A/CYBB/HLA-DQB2/KIF11/HLA-DMA/CD1C/KLC1/FCGR1A/HLA-H/CENPE/CD207/HLA-G/PSMD8/CD1B/KIF4B/PSMD1/PSMD2/CD74/CD1D/CTSF/PSMF1/DCTN5/HLA-DPA1/HLA-E/HLA-DRA/AP3D1/AP1S1/PSMD9/AP2S1/SNAP23/CTSD/PSMA5/LAG3/TAP1/CAPZA1/KIF3C/PSMB7/VAMP3/PSMD5/HLA-DMB/CYBA/HLA-DQA2/PSME2/PSMB5/ACTR1A/CANX/LNPEP/PSMB4/HLA-DPB1/TRAF6/PSMA3/NCF1/PSMD10/PSMB1/PSMD7/PSMB3/HLA-DRB1/PSMC5/PSMD11	72
BP	GO:0046939	nucleotide phosphorylation	57/4749	136/18670	1.89e-05	0.001085	0.0008829	TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/GPI/CBFA2T3/SIRT6/HK2/NUP98/ENTPD5/CMPK2/STAT3/DTYMK/PGM2L1/PKM/AK5/ALDOC/OGDH/HTR2A/PFKFB4/NUP153/NME4/DDIT4/GALK1/PFKFB2/NUP88/ENO3/PRKAG2/NME3/POM121C/AK4/NUP205/RAE1/NUP50/ALDOA/GUK1/AK1/CMPK1/INSR/NUPR1/NUP93/PFKL/ALDOB/NUP35/NME9/AAAS/NUP62/P2RX7/SEH1L/NCOR1/NME2	57
BP	GO:0042770	signal transduction in response to DNA damage	56/4749	133/18670	1.897e-05	0.001085	0.0008829	TWIST1/GTSE1/E2F7/E2F8/FOXM1/CDK1/CDKN1A/DTL/CASP9/AURKA/BATF/BCL3/TREX1/SPRED2/DYRK3/ZNF385A/PML/E2F1/PLK2/BRCA2/BAX/PLK1/CDC25C/GADD45A/PMAIP1/MSX1/CCNB1/SNAI1/SFN/RPL26/CDK2/CD74/BID/CARM1/NDRG1/CNOT3/TFDP2/MUC1/MDM4/BRCC3/CHEK1/CD44/ACER2/RBL2/PRPF19/CNOT7/CDC5L/CDC14B/GML/MAD2L2/ATR/CHEK2/ATM/PSMD10/SESN2/SIRT1	56
BP	GO:0045670	regulation of osteoclast differentiation	32/4749	64/18670	2.053e-05	0.001164	0.0009469	RASSF2/IL17A/CCR1/TNF/CSF1/TLR4/PIAS3/MTOR/ESRRA/PPARGC1B/TFE3/LILRB4/GNAS/CCL3/TOB2/CA2/CEBPB/KLF10/IL20/BGLAP/SFRP1/IL4/TYROBP/TRAF6/TNFSF11/FOS/SLC9B2/ZNF675/TMEM64/POU4F1/TCTA/IL23A	32
BP	GO:0042102	positive regulation of T cell proliferation	43/4749	95/18670	2.126e-05	0.001195	0.0009718	EBI3/IL1B/CD86/IL18/CD276/IL21/CD80/TNFSF4/TFRC/LGALS9/HMGB1/IL2RA/FOXP3/CCR2/HAVCR2/CD1D/RPS3/EFNB1/PNP/DNAJA3/HLA-DPA1/PTPRC/CORO1A/HLA-E/AIF1/LILRB2/IL12RB1/CD46/HLA-DMB/TNFSF9/PDCD1LG2/CD3E/CCDC88B/CARD11/IL4/RIPK2/CD6/HLA-DPB1/TRAF6/JAK3/HHLA2/ZAP70/IL23A	43
BP	GO:0006165	nucleoside diphosphate phosphorylation	56/4749	134/18670	2.46e-05	0.001368	0.001113	TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/GPI/CBFA2T3/SIRT6/HK2/NUP98/ENTPD5/CMPK2/STAT3/DTYMK/PGM2L1/PKM/AK5/ALDOC/OGDH/HTR2A/PFKFB4/NUP153/NME4/DDIT4/GALK1/PFKFB2/NUP88/ENO3/PRKAG2/NME3/POM121C/AK4/NUP205/RAE1/NUP50/ALDOA/AK1/CMPK1/INSR/NUPR1/NUP93/PFKL/ALDOB/NUP35/NME9/AAAS/NUP62/P2RX7/SEH1L/NCOR1/NME2	56
BP	GO:0002718	regulation of cytokine production involved in immune response	39/4749	84/18670	2.477e-05	0.001368	0.001113	IL1B/IL18/NR4A3/NLRP3/IL10/IL1R1/BCL6/HK1/TNFSF4/TNF/SEMA7A/TLR4/FOXP3/RSAD2/SMAD7/FFAR2/CCR2/HMOX1/HLA-G/BTK/BST2/TGFB3/CD74/TRIL/FFAR3/IRAK3/TRPM4/HLA-E/NOD2/ARG1/IL18R1/TRAF2/TNFRSF1B/TRAF6/FZD5/TGFB1/JAK3/CD96/GATA3	39
BP	GO:0072401	signal transduction involved in DNA integrity checkpoint	35/4749	73/18670	2.727e-05	0.00148	0.001204	GTSE1/E2F7/E2F8/CDK1/CDKN1A/DTL/AURKA/TREX1/ZNF385A/PML/E2F1/PLK2/BAX/PLK1/CDC25C/GADD45A/CCNB1/SFN/RPL26/CDK2/CARM1/CNOT3/TFDP2/MUC1/MDM4/BRCC3/CHEK1/RBL2/PRPF19/CNOT7/CDC5L/CDC14B/GML/CHEK2/ATM	35
BP	GO:0072422	signal transduction involved in DNA damage checkpoint	35/4749	73/18670	2.727e-05	0.00148	0.001204	GTSE1/E2F7/E2F8/CDK1/CDKN1A/DTL/AURKA/TREX1/ZNF385A/PML/E2F1/PLK2/BAX/PLK1/CDC25C/GADD45A/CCNB1/SFN/RPL26/CDK2/CARM1/CNOT3/TFDP2/MUC1/MDM4/BRCC3/CHEK1/RBL2/PRPF19/CNOT7/CDC5L/CDC14B/GML/CHEK2/ATM	35
BP	GO:0070663	regulation of leukocyte proliferation	84/4749	222/18670	2.804e-05	0.00151	0.001228	EBI3/IL1B/CD86/SDC4/IL18/CD276/IL21/CDKN1A/IL10/CD80/PTPN6/BCL6/TIRAP/TNFSF4/TFRC/MZB1/LGALS3/GPNMB/LGALS9/HMGB1/CSF1/TNFRSF4/IL2RA/TLR4/BTN2A2/TNFRSF21/FOXP3/CTLA4/RIPK3/CCR2/HLA-G/BTK/BST2/HAVCR2/CD74/CD1D/RPS3/EFNB1/CLEC4G/PNP/DNAJA3/HLA-DPA1/PTPRC/CORO1A/HLA-E/AIF1/LILRB2/IL12RB1/ARG1/TNFRSF13B/CD46/MNDA/ERBB2/IL5RA/RAC2/CEBPB/IDO1/HLA-DMB/SOX11/TNFSF9/PDCD1LG2/IL7/CD3E/IL13/DLG5/CCDC88B/CARD11/IL4/PRNP/RIPK2/TNFRSF1B/TYROBP/CD6/HLA-DPB1/TRAF6/ATM/SLC39A10/TGFB1/GLMN/JAK3/HHLA2/ZAP70/LRRC32/IL23A	84
BP	GO:0032663	regulation of interleukin-2 production	28/4749	54/18670	2.838e-05	0.001514	0.001232	IL1B/CD86/CD83/CD80/IRF4/CLEC7A/ZFP36/FOXP3/HOMER2/CARD9/CCR2/PDE4D/HAVCR2/PDE4B/RPS3/SPTBN1/PTPRC/EZR/LAG3/CD3E/TRAF2/CARD11/CD34/PRNP/RIPK2/TRAF6/GLMN/GATA3	28
BP	GO:0048871	multicellular organismal homeostasis	163/4749	485/18670	2.886e-05	0.001514	0.001232	EGR1/G0S2/NCDN/IL1B/VEGFA/NOTCH1/PLAC8/IL18/NR4A3/GADD45G/CSF1R/ACP5/SRF/RAC1/IRF4/CTSH/TP53INP2/TFRC/BBS2/PCTP/SPP1/TP63/THRA/ACOT11/TNF/CSF1/SIRT6/LRRK1/CDH23/TLR4/AKT3/BAX/TPP1/ARRDC3/CCDC66/HOMER2/GPX1/WNT10B/ACTG1/STAT3/IL4R/ADCY4/CCR2/SRC/SCD/HCRT/FA2H/PPARGC1B/TFE3/HOMER1/SFN/ABAT/SPATA7/FABP5/GNAS/HTR2A/LYZ/UBB/IGF1R/WWTR1/RAB3D/RBPJ/ADCY6/ATF4/PER2/CRTC1/MAP2K6/ACSL1/PRDM16/S1PR1/FOXO1/MDM1/AQP2/PRKAB2/KSR2/PRKCA/CORO1A/PIGR/STMN1/TLE3/CNOT3/ADIPOR2/USH1G/PRCP/MKKS/NOD2/DRD1/GBA/ADIPOR1/PLCL2/DDIT3/RCN3/AMPD2/NAPSA/IL18R1/PLEKHM1/CNR1/NTSR1/TFAP2B/CUBN/ACVR2B/ACER1/TSHR/ZG16B/CA2/BBS12/RAC2/EPAS1/CEBPB/ELOVL1/ADCY3/NDN/ARNTL/YAP1/IL7/ALMS1/TFF1/LACRT/ZNF830/IL13/LCN1/BGLAP/GHRL/CYP4F12/AMPD3/IP6K1/ADIPOQ/GIGYF2/IL4/BSCL2/TNFRSF11B/CD34/PTH2R/F2R/ACACB/LNPEP/PRKACB/TRAF6/ADCY9/APC/LIPA/TMEM119/TNFSF11/DLL1/ZNF675/ID1/METRNL/TMEM64/HAS2/PGAM5/OMA1/CLDN4/SLC40A1/LDB1/P2RX7/ANKRD11/PRDX1/LPIN1/BARD1/MC3R/RAC3/PIWIL4/ACTB	163
BP	GO:0046777	protein autophosphorylation	88/4749	235/18670	2.89e-05	0.001514	0.001232	AURKB/VEGFA/TTK/TYRO3/WNK1/MVP/AURKA/NTRK2/CSF1R/FES/RASSF2/NTRK1/MELK/PDGFA/NEK2/HCK/EPHB1/PIM3/SLA/DAPK2/CDK5/GPNMB/BLK/MTOR/MYLK2/PIM1/RIPK3/SRC/EPHB4/BTK/PIM2/ATP13A2/CAMK2A/IGF1R/PAK1/FLT3/STK16/IRAK3/PRKX/PTK6/PINK1/PTPRC/ULK1/MAP3K11/TXK/AAK1/IRAK1/THY1/FLT1/TAOK3/INSRR/CHP1/STK25/JUN/MKNK1/ERBB2/MAP3K3/MINK1/DDR1/ITK/FLT4/DAPK1/EIF2AK3/CAMK2D/ADIPOQ/MAP4K1/CLK3/ERN1/MAPKAPK2/FER/UHMK1/GRK5/ATR/CHEK2/INSR/BCR/STK17B/ATM/MAP3K9/TOM1L1/CLK2/CSNK1G2/PDGFB/ZAP70/VEGFC/FYN/NME2/PAK2	88
BP	GO:0046902	regulation of mitochondrial membrane permeability	36/4749	76/18670	2.931e-05	0.001514	0.001232	PPIF/TP73/BNIP3L/YWHAH/YWHAE/TP63/YWHAZ/E2F1/HK2/HSPA1A/NOL3/BAX/PMAIP1/NAIF1/CNP/STAT3/MOAP1/SFN/BMF/CAMK2A/HIP1R/EYA2/NMT1/BID/TFDP2/BAK1/YWHAQ/SLC25A5/STPG1/ZNF205/BCL2L1/GSK3A/RHOT2/FZD9/SPG7/BAD	36
BP	GO:0032943	mononuclear cell proliferation	100/4749	274/18670	2.931e-05	0.001514	0.001232	EBI3/IL1B/CD86/SDC4/IL18/CD276/IL21/CDKN1A/IL10/CD80/PTPN6/BCL6/TIRAP/TNFSF4/TFRC/MZB1/LGALS3/GPNMB/LGALS9/HMGB1/CSF1/TNFRSF4/IL2RA/TLR4/BAX/BTN2A2/TNFRSF21/FOXP3/CTLA4/DOCK8/RIPK3/CCR2/HLA-G/RPS6/BTK/HAVCR2/CD74/HPRT1/CD1D/RPS3/EFNB1/CLEC4G/FLT3/SATB1/CD180/PNP/DNAJA3/HLA-DPA1/PTPRC/CORO1A/HLA-E/AIF1/LILRB2/IL12RB1/PLCL2/ARG1/CD19/TNFRSF13B/CD46/MNDA/CR2/ERBB2/RAC2/CD151/AZI2/CEBPB/IL7R/IDO1/HLA-DMB/SOX11/TNFSF9/PDCD1LG2/HELLS/IMPDH1/IL7/CD3E/IL13/DLG5/CCDC88B/CARD11/IL4/PRNP/RIPK2/TNFRSF1B/TYROBP/CD6/HLA-DPB1/TRAF6/ATM/RAG2/SLC39A10/TGFB1/GLMN/JAK3/HHLA2/ZAP70/P2RX7/LRRC32/FYN/IL23A	100
BP	GO:0010212	response to ionizing radiation	60/4749	147/18670	3.012e-05	0.001544	0.001256	EGR1/TICRR/CDKN1A/ICAM1/TREX1/RAD54L/PML/HSPA5/BRCA2/BAX/CXCL10/BRAT1/GADD45A/GPX1/RAD51/RAD51AP1/RPL26/TP53BP1/RRM1/RFWD3/TOPBP1/XRCC6/NAMPT/PTPRC/ERCC8/FIGNL1/TRIM13/BAK1/TANK/RNF8/BRCC3/ELK1/ECT2/AEN/BCL2L1/CYBA/YAP1/IFI16/SFRP1/NHEJ1/ATR/CHEK2/MTA1/GTF2H5/CCL7/ATM/NUCKS1/WRN/TGFB1/CLK2/NET1/MGMT/CCND1/INIP/GATA3/ERCC1/FBXO4/RNF168/RAD9A/SIRT1	60
BP	GO:0051225	spindle assembly	47/4749	108/18670	3.16e-05	0.001607	0.001307	AURKB/GPSM2/TPX2/KIFC1/ASPM/KIF4A/BIRC5/AURKA/KIF23/NEK2/CDC20/MYBL2/SPAG5/RACGAP1/SAC3D1/SMC3/CENPW/CHMP2B/HSPA1A/KIF11/PLK1/TUBB/MAPRE2/FBXO5/NUMA1/KIF4B/MSTO1/RPS3/TUBGCP2/PIBF1/CEP192/RCC1/HAUS5/WRAP73/CHMP1A/CCDC69/CHEK2/CHMP2A/SMC1A/MAP9/SENP6/AAAS/STARD9/TUBGCP5/CEP97/NCOR1/TUBGCP3	47
BP	GO:0043087	regulation of GTPase activity	161/4749	479/18670	3.202e-05	0.001615	0.001314	CXCL13/IQGAP3/RGS16/RASGRP2/TIAM2/RINL/WNK1/ICAM1/ARHGAP23/NTRK2/GPSM1/NEDD9/ADPRH/SIPA1L1/CCL20/NTRK1/CCL3L3/BCL6/PLXNB2/CCL22/SBF1/RACGAP1/CORO1C/SGSM3/ELMOD1/DEPDC1B/RTKN/TBC1D9/PLXNB1/SNX9/SRGAP2/FGD2/SIPA1L2/RGPD2/CDC42SE1/ASAP2/MTOR/ARHGAP9/DOCK8/TBC1D2B/ARHGEF12/MAPRE2/ARHGEF5/RHOG/TIAM1/ARHGAP11A/ARRB1/RIC8A/CCL3/DOCK1/NTRK3/DVL3/ARHGAP31/TBC1D22A/PLXNA1/ARHGAP11B/ARHGAP19/LIMS1/AMOT/DOCK5/ARHGAP35/TBC1D10C/S1PR1/CCL2/STMN3/STARD13/ARHGAP5/STXBP5/RASAL2/PREX1/RUNDC1/CCL17/SBF2/TBC1D3H/VAV2/TBC1D20/ARHGAP4/TBC1D10B/RASA3/CCL18/PLXND1/ITGA6/EZH2/VPS9D1/PKP4/CCDC125/SCRIB/S100A10/MKKS/TBC1D8/IQSEC1/ARAP1/THY1/AGAP5/ADAP2/ARHGAP15/ACAP1/RAPGEF1/SRGAP3/JUN/ARAP3/SH3BP4/RASA4/TBC1D22B/ERBB2/AGAP2/CRK/ARHGAP33/ECT2/NUP50/TBC1D2/MYO9B/RGS1/FICD/RGL3/RASAL1/RAPGEF2/CHN1/NPRL3/SFRP1/RAP1GAP2/F2R/DOCK9/SEMA4D/TBC1D13/GNAQ/CCL23/TBCK/ARHGAP18/ARHGDIA/ARHGAP17/TBC1D3C/RGS5/BCR/RIN2/ARL2/CCL7/NTF3/ARHGAP24/CHN2/ARHGAP1/DEPDC1/RIC8B/PIP5K1A/ARHGAP32/ALS2CL/PLCB1/BCAS3/CCL15/BNIP2/NET1/RTN4R/PGAM5/RGPD1/KLRK1/RALGAPA1/GDI1/USP17L2/RALBP1/RGS7/NPRL2	161
BP	GO:0046031	ADP metabolic process	53/4749	126/18670	3.237e-05	0.00162	0.001318	TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/GPI/CBFA2T3/SIRT6/HK2/NUP98/ENTPD5/STAT3/PGM2L1/PKM/AK5/ALDOC/OGDH/HTR2A/PFKFB4/NUP153/AK3/DDIT4/GALK1/PFKFB2/NUP88/ENO3/PRKAG2/POM121C/AK4/NUP205/RAE1/NUP50/ALDOA/AMPD3/AK1/INSR/NUPR1/NUP93/PFKL/ALDOB/NUP35/AAAS/AK2/NUP62/P2RX7/SEH1L/NCOR1/BAD	53
BP	GO:0016925	protein sumoylation	38/4749	82/18670	3.299e-05	0.001638	0.001333	EGR1/EGR2/BCL11A/NUP98/PIAS3/SAE1/SUMO4/UBE2I/SUMO3/NUP153/TOLLIP/PIAS1/TRPM4/NUP88/GNL3/SUMO1/PARK7/RASD2/TOPORS/POM121C/KIAA1586/NUP205/RAE1/HMG20A/PIAS2/NUP50/PIAS4/SUMO1P1/NUP93/HMG20B/SENP6/NUP35/AAAS/RNF212/ZNF451/NUP62/SEH1L/MAGEA2B	38
BP	GO:0043547	positive regulation of GTPase activity	139/4749	405/18670	3.541e-05	0.001739	0.001415	CXCL13/RGS16/RASGRP2/TIAM2/RINL/ICAM1/ARHGAP23/NEDD9/ADPRH/SIPA1L1/CCL20/NTRK1/CCL3L3/CCL22/RACGAP1/CORO1C/SGSM3/ELMOD1/DEPDC1B/TBC1D9/PLXNB1/SNX9/SRGAP2/SIPA1L2/RGPD2/ASAP2/ARHGAP9/DOCK8/TBC1D2B/ARHGEF12/MAPRE2/ARHGEF5/RHOG/TIAM1/ARHGAP11A/ARRB1/RIC8A/CCL3/DOCK1/NTRK3/DVL3/ARHGAP31/TBC1D22A/ARHGAP11B/ARHGAP19/LIMS1/DOCK5/ARHGAP35/TBC1D10C/S1PR1/CCL2/STARD13/ARHGAP5/STXBP5/RASAL2/PREX1/RUNDC1/CCL17/TBC1D3H/TBC1D20/ARHGAP4/TBC1D10B/RASA3/CCL18/ITGA6/EZH2/VPS9D1/PKP4/CCDC125/SCRIB/S100A10/TBC1D8/IQSEC1/ARAP1/THY1/AGAP5/ADAP2/ARHGAP15/ACAP1/RAPGEF1/SRGAP3/JUN/ARAP3/RASA4/TBC1D22B/ERBB2/AGAP2/CRK/ARHGAP33/ECT2/NUP50/TBC1D2/MYO9B/RGS1/RGL3/RASAL1/RAPGEF2/CHN1/NPRL3/SFRP1/RAP1GAP2/F2R/DOCK9/SEMA4D/TBC1D13/GNAQ/CCL23/TBCK/ARHGAP18/ARHGDIA/ARHGAP17/TBC1D3C/RGS5/BCR/RIN2/CCL7/NTF3/ARHGAP24/CHN2/ARHGAP1/DEPDC1/RIC8B/PIP5K1A/ARHGAP32/ALS2CL/PLCB1/BCAS3/CCL15/BNIP2/NET1/RTN4R/PGAM5/RGPD1/RALGAPA1/GDI1/USP17L2/RALBP1/RGS7/NPRL2	139
BP	GO:1904951	positive regulation of establishment of protein localization	154/4749	456/18670	3.582e-05	0.001739	0.001415	TWIST1/IL1B/MAPK11/GTSE1/TP73/NLRP3/ADORA2A/CSF1R/IL10/ABCG1/KIF20B/RAC1/TLR8/IL17A/GAPDH/HK1/TNFSF4/YWHAH/CAMK1/CDK5/YWHAE/TP63/LGALS9/RBM22/YWHAZ/GPI/MYH10/HMGB1/TNF/E2F1/TNFRSF4/BLK/TLR4/CENPJ/LILRA2/PMAIP1/MMP12/IL4R/FFAR2/FRMD4A/SORL1/USP36/FCN1/SRC/SAE1/TENM1/SEC16A/ARHGEF5/B3GAT3/SFN/ABAT/ARRB1/CCL3/ATP13A2/PTGER4/HAVCR2/C2CD2L/SRI/CD33/TGFB3/PAK1/BAP1/PDCD5/CCT5/NMT1/CASR/HPS4/TCF7L2/BID/PINK1/SPTBN1/EZR/BCAP31/TRPM4/NADK/HLA-E/AIF1/OXCT1/TLR2/KCNN4/TFDP2/PFKFB2/CD58/NOD2/PSMD9/LRP1/TMEM30A/IL26/OSM/CADM1/SIRT3/YWHAQ/C1QTNF3/CHP1/EMD/EFCAB7/ERBB2/IL17RC/OAZ2/PRKCE/RAC2/ECT2/EDEM2/IRF3/GLUD1/ZC3H12A/BAG3/PAEP/LILRA5/GSK3A/IL13/RHOU/UBL5/WRAP53/CD2AP/IFNGR1/GHRL/CD34/PRNP/RIPK2/MYOM1/F2R/SERP1/DOC2B/HSPA1L/CLEC5A/ARF6/OAZ1/CARD8/PARD6A/FZD5/STOM/PPARD/FFAR1/ZFAND1/RUFY3/TGFB1/BCAS3/CNST/GLMN/MAPK1/ADAM9/TRIM16/GATA3/PDX1/P2RX7/GIPR/SREBF2/SYBU/VEGFC/BAD/FYN/PTP4A3/CCT3	154
BP	GO:0010821	regulation of mitochondrion organization	71/4749	182/18670	3.614e-05	0.001739	0.001415	PPIF/TP73/SQSTM1/BNIP3L/PLAUR/MLLT11/YWHAH/PRELID1/MMP9/YWHAE/TP63/YWHAZ/DHODH/E2F1/HK2/HSPA1A/CTTN/NOL3/BAX/PMAIP1/GPX1/BAG4/LMNA/TSPO/USP36/FXN/SAE1/MOAP1/SFN/BMF/ATP13A2/CLU/BAP1/HTT/HIP1R/PDCD5/BIK/PARL/NMT1/HPS4/SMURF1/BID/PINK1/TFDP2/BAK1/GBA/YWHAQ/VDAC1/PARK7/SLC25A5/RAC2/ZNF205/BCL2L1/BAG3/GSK3A/RHOU/UBL5/CIDEB/TNFSF10/RHOT2/FZD9/HSPA1L/PAM16/VPS13D/FZD5/PSMD10/ATG7/OMA1/SREBF2/BAD/MGARP	71
BP	GO:0046651	lymphocyte proliferation	99/4749	272/18670	3.629e-05	0.001739	0.001415	EBI3/IL1B/CD86/SDC4/IL18/CD276/IL21/CDKN1A/IL10/CD80/PTPN6/BCL6/TIRAP/TNFSF4/TFRC/MZB1/LGALS3/GPNMB/LGALS9/HMGB1/TNFRSF4/IL2RA/TLR4/BAX/BTN2A2/TNFRSF21/FOXP3/CTLA4/DOCK8/RIPK3/CCR2/HLA-G/RPS6/BTK/HAVCR2/CD74/HPRT1/CD1D/RPS3/EFNB1/CLEC4G/FLT3/SATB1/CD180/PNP/DNAJA3/HLA-DPA1/PTPRC/CORO1A/HLA-E/AIF1/LILRB2/IL12RB1/PLCL2/ARG1/CD19/TNFRSF13B/CD46/MNDA/CR2/ERBB2/RAC2/CD151/AZI2/CEBPB/IL7R/IDO1/HLA-DMB/SOX11/TNFSF9/PDCD1LG2/HELLS/IMPDH1/IL7/CD3E/IL13/DLG5/CCDC88B/CARD11/IL4/PRNP/RIPK2/TNFRSF1B/TYROBP/CD6/HLA-DPB1/TRAF6/ATM/RAG2/SLC39A10/TGFB1/GLMN/JAK3/HHLA2/ZAP70/P2RX7/LRRC32/FYN/IL23A	99
BP	GO:0044786	cell cycle DNA replication	34/4749	71/18670	3.647e-05	0.001739	0.001415	E2F7/E2F8/CDT1/BCL6/MCM4/MCM5/GMNN/SMC3/MSH6/BRCA2/FEN1/RAD51/MCM2/FBXO5/DBF4/DBF4B/CDC45/GINS1/UPF1/RFC2/MCM7/TERF1/POLD4/AICDA/POLE/MCM3/ZNF830/DNA2/CHEK2/SMC1A/WIZ/TIPIN/POLE2/TERF2	34
BP	GO:0002294	CD4-positive, alpha-beta T cell differentiation involved in immune response	30/4749	60/18670	3.692e-05	0.001739	0.001415	CD86/IL18/RELB/NLRP3/BATF/CD80/IRF4/BCL3/BCL6/TNFSF4/LGALS9/HMGB1/MTOR/FOXP3/STAT3/IL4R/SMAD7/PTGER4/LY9/HLX/RORC/IL12RB1/IL18R1/ZC3H12A/RIPK2/JAK3/RARA/ZFPM1/GATA3/IL23A	30
BP	GO:0051306	mitotic sister chromatid separation	30/4749	60/18670	3.692e-05	0.001739	0.001415	ESPL1/CENPF/AURKB/BUB1B/TTK/CDT1/TRIP13/CDC20/PTTG1/DLGAP5/BUB1/TACC3/CDC6/PPP2R1A/PLK1/CCNB1/CENPE/FBXO5/NDC80/DIS3L2/ANAPC11/USP44/ANAPC1/XRCC3/NCAPH2/MAD2L2/KLHL22/APC/ATM/DUSP1	30
BP	GO:0007249	I-kappaB kinase/NF-kappaB signaling	98/4749	269/18670	3.798e-05	0.001772	0.001442	NDFIP2/IL1B/RELB/SQSTM1/BCL3/TLR8/IL1RN/SIRPA/TIRAP/TIFA/CANT1/LGALS9/UBD/TNF/PLK2/TLR4/S100A13/TRIM25/IFIT5/CARD9/RIPK3/HMOX1/TGM2/CFLAR/TRIM62/BTK/UBE2I/PIM2/BST2/UBB/CD74/UBE2N/CTH/LGALS1/TRIM22/RPS27A/TNFRSF19/TNFRSF10B/TIFAB/PINK1/SLC35B2/BRD4/UBA52/TLR2/TRIM13/SECTM1/LITAF/NOD2/FKBP1A/TANK/IRAK1/OTUD7B/TLR6/MID2/PPP5C/TAB1/NFKBIA/PRKCE/AZI2/ECT2/NFKBIL1/NLRC3/MAP3K3/IRF3/ZC3H12A/BIRC3/TMED4/TNIP3/BTRC/TRAF2/CARD11/ADIPOQ/RIPK2/ESR1/F2R/TNFSF10/IL36A/PRKCB/TRAF6/SPHK2/AKAP13/GOLT1B/TSPAN6/STAT1/CARD8/TNFSF11/EDAR/SHISA5/ZNF675/ANKRD17/NUP62/CX3CR1/FYN/IRAK1BP1/IL37/ZFAND6/SIRT1/TRIM5	98
BP	GO:0006310	DNA recombination	105/4749	292/18670	3.818e-05	0.001772	0.001442	HMGB3/RBBP8/TOP2A/IL10/BATF/EXO1/TRIP13/BCL6/MCM4/TREX1/TNFSF4/TFRC/MCM5/TFPT/SFPQ/RAD54L/KPNA2/SYCE3/HMGB1/SIRT6/APEX2/MSH6/BRCA2/UBE2B/AP5S1/ZSWIM7/FOXP3/FEN1/RAD51/RAD51AP1/SWAP70/CCR6/PARPBP/MCM2/RMI2/TONSL/TP53BP1/CDC45/PIF1/GINS2/DMC1/MND1/POLQ/RFWD3/MAGEF1/GINS4/XRCC6/UBE2N/ACTL6A/ZRANB3/MCM7/PTPRC/HELQ/EID3/FIGNL1/TIMELESS/SUPT6H/RECQL5/AICDA/IL27RA/RNF8/MCM3/ERCC2/REC8/CHEK1/MCRS1/IL7R/APLF/RECQL4/UCHL5/SAMHD1/POLM/XRCC3/XRCC1/EME1/KLHDC3/SFR1/WRAP53/AUNIP/TNFSF13/IL4/UBR2/MAD2L2/HELB/ANKRD31/RAD52/POLN/ATM/NUCKS1/WDR48/MLH3/WRN/SMC5/RAG2/FAN1/RNF138/TGFB1/RNF212/WAS/HDAC10/ERCC1/RNF168/TERF2/RAD54B/TSN	105
BP	GO:0043367	CD4-positive, alpha-beta T cell differentiation	35/4749	74/18670	3.916e-05	0.001805	0.001468	CD86/IL18/RELB/NLRP3/BATF/CD83/CD80/IRF4/BCL3/BCL6/CBFB/TNFSF4/LGALS9/HMGB1/MTOR/FOXP3/STAT3/IL4R/RSAD2/SMAD7/PTGER4/LY9/HLX/SATB1/RORC/IL12RB1/IL18R1/ZC3H12A/RIPK2/PAX1/JAK3/RARA/ZFPM1/GATA3/IL23A	35
BP	GO:0030316	osteoclast differentiation	43/4749	97/18670	3.951e-05	0.001808	0.001471	CD109/CSF1R/RASSF2/IL17A/TFRC/CCR1/ANXA2P2/TNF/CSF1/LRRK1/TLR4/PIAS3/MTOR/GAB2/ANXA2/ESRRA/SBNO2/SRC/PPARGC1B/TFE3/LILRB4/GNAS/CCL3/FAM20C/TOB2/CA2/CEBPB/KLF10/IL20/BGLAP/SFRP1/IL4/TYROBP/TRAF6/TNFSF11/FOS/SLC9B2/ZNF675/TGFB1/TMEM64/POU4F1/TCTA/IL23A	43
BP	GO:0031571	mitotic G1 DNA damage checkpoint	31/4749	63/18670	4.106e-05	0.001852	0.001507	GTSE1/E2F7/E2F8/CDK1/CDKN1A/AURKA/ZNF385A/PML/E2F1/PLK2/BAX/CDC25C/GADD45A/CCNB1/SFN/RPL26/CDK2/RFWD3/FBXO31/CARM1/CNOT3/TFDP2/MUC1/MDM4/RBL2/CNOT7/GIGYF2/GML/CHEK2/ATM/CCND1	31
BP	GO:0044819	mitotic G1/S transition checkpoint	31/4749	63/18670	4.106e-05	0.001852	0.001507	GTSE1/E2F7/E2F8/CDK1/CDKN1A/AURKA/ZNF385A/PML/E2F1/PLK2/BAX/CDC25C/GADD45A/CCNB1/SFN/RPL26/CDK2/RFWD3/FBXO31/CARM1/CNOT3/TFDP2/MUC1/MDM4/RBL2/CNOT7/GIGYF2/GML/CHEK2/ATM/CCND1	31
BP	GO:0051403	stress-activated MAPK cascade	103/4749	286/18670	4.194e-05	0.001879	0.001528	IL1B/PBK/MAPK11/VEGFA/FOXM1/DUSP10/GADD45G/TRIB1/RASSF2/EPHB1/IL1RN/SIRPA/TIRAP/DNAJA1/LGALS9/SEMA4C/HMGB1/TNF/ZFP36/FGD2/TLR4/PTPN1/GADD45A/CARD9/NBR1/PDCD4/MAP3K6/ARHGEF5/TIAM1/MAP2K3/SDCBP/MAP3K2/PTGER4/DVL3/UBB/IGF1R/PAK1/UBE2N/RPS3/FKTN/RPS27A/FOXO1/TNFRSF19/CASR/FAS/MAP3K5/PINK1/EZR/CYLD/STK3/NRK/UBA52/DUSP22/NOD2/TRAF4/MAP3K11/IRAK1/MID1/DTNBP1/IL26/TAOK3/WNT7A/TLR6/FZD8/RAPGEF1/STK25/SH2D3A/FBXW11/TAB1/SH2D3C/PHLPP1/MAP3K3/ZC3H12A/MINK1/MAP2K4/FLT4/BTRC/EMC10/SFRP1/TRAF2/MAP4K1/ERN1/RIPK2/MAPKAPK2/IL36A/ZFP36L1/AIDA/TRAF6/BIRC7/MIR181D/TNFSF11/EDAR/FZD5/NCF1/ZNF675/MAP3K9/PLCB1/MAPK1/NCOR1/PRDX1/IL37/PJA2/DUSP1	103
BP	GO:0001818	negative regulation of cytokine production	106/4749	296/18670	4.272e-05	0.0019	0.001546	TWIST1/FURIN/RELB/NLRP3/KLF2/IL10/CD83/ACP5/KLF4/RAC1/PTPN6/ISG15/BCL3/TLR8/BCL6/SIRPA/TNFSF4/GPNMB/CEACAM1/LGALS9/PML/HMGB1/TNF/ZFP36/TNFRSF4/CD200/TLR4/BTN2A2/TNFRSF21/TRIM25/FOXP3/HOMER2/ABCD1/IL1R2/SMAD7/PDCD4/TSPO/HMOX1/ABCD2/MERTK/TRAIP/ARRB1/BTK/TIGIT/PTGER4/BST2/HAVCR2/AXL/CD33/TGFB3/UBA7/IRAK3/NPLOC4/C5orf30/PGLYRP3/PTPRC/SIGIRR/EZR/CYLD/GBA/IL27RA/NDRG2/OTUD7B/ARG1/LAG3/C1QTNF3/TLR6/RNF216/ANXA4/PIBF1/DEFB114/SYT11/NFKBIL1/IDO1/SRGN/NLRC3/IRF3/PDCD1LG2/ZC3H12A/RABGEF1/LILRA5/IL13/CD2AP/GHRL/CHID1/ADIPOQ/IL4/CD34/PRNP/PTPRS/TYROBP/DICER1/C1QBP/HDAC9/CARD8/DLL1/TGFB1/ASB1/JAK3/RARA/CD96/ZFPM1/GATA3/CX3CR1/LRRC32/IL23A	106
BP	GO:0072697	protein localization to cell cortex	10/4749	12/18670	4.399e-05	0.001934	0.001573	SAPCD2/GPSM2/ANLN/RTKN/PLK1/NUMA1/NUBP1/EZR/EPB41L2/EPB41	10
BP	GO:1901990	regulation of mitotic cell cycle phase transition	150/4749	444/18670	4.407e-05	0.001934	0.001573	ESPL1/CENPF/AURKB/TPX2/KIF14/ANLN/GTSE1/E2F7/E2F8/CDCA5/UBE2C/BUB1B/TTK/TICRR/CDK1/CDT1/CDKN1A/DTL/AURKA/HSPA2/KANK2/CDKN2B/KLF4/NEK2/PTPN6/TRIP13/CDC20/DLGAP5/CLSPN/BUB1/ZNF385A/GPNMB/CDC25A/YWHAE/UBD/CDC6/PLK4/PPP2R1A/PML/E2F1/PLK2/ODF2/BAX/BTN2A2/PLK1/CDC25C/CDKN2C/GADD45A/CENPJ/WNT10B/TUBB/CCNB1/CENPE/FGFR1OP/FBXO5/NDC80/SFN/RPL26/DBF4B/PSMD8/CDC45/CDK2/PSMD1/TUBB4B/PSMD2/ORC1/RFWD3/CDK2AP2/PKD2/TOPBP1/PSMF1/CCL2/ZFP36L2/FBXO31/CEP152/BID/CARM1/CEP70/AIF1/BRD4/CNOT3/EZH2/CDK10/SFI1/TFDP2/MUC1/CDKN2A/PSMD9/PSMA5/MDM4/TAOK3/ANAPC11/PSMB7/ERCC2/TUBB4A/USP44/GPR132/CEP192/PSMD5/MIIP/RBL2/ALMS1/ANAPC1/XRCC3/ZNF830/PSME2/CNOT7/HAUS5/BTRC/TMEM14B/SIRT2/GIGYF2/PSMB5/CDC14B/ACTR1A/GML/NAE1/TUBG1/ZFP36L1/MAD2L2/CETN2/CHEK2/PSMB4/CEP72/KLHL22/PSMA3/APC/PBX1/PPP1R9B/MTA3/ADAMTS1/ATM/ANKRD17/PSMD10/PLCB1/TGFB1/CUL4A/PSMB1/PSMD7/ZNF655/PSMB3/CDC25B/CCND1/SYF2/CDC16/PSMC5/CKAP5/NINL/PSMD11/DUSP1	150
BP	GO:0072331	signal transduction by p53 class mediator	97/4749	267/18670	4.699e-05	0.002039	0.001658	TWIST1/AURKB/TPX2/MAPK11/GTSE1/E2F7/E2F8/TP73/FOXM1/CDK1/RBBP8/CDKN1A/AURKA/BATF/E2F2/PHLDA3/TOP3A/EXO1/BCL3/SPRED2/HEXIM1/PERP/DYRK3/ZNF385A/RFFL/CDK5/TP63/PML/E2F1/PLK2/RRM2B/BRCA2/BAX/CDC25C/GADD45A/PMAIP1/MSX1/ING5/CCNB1/RMI2/SNAI1/RPL5/SFN/RPL26/CDK2/UBB/CD74/TOPBP1/RFC2/CARM1/PRKAB2/TAF1L/RPL23/NDRG1/DDIT4/CNOT3/TFDP2/TAF9B/MUC1/TP53INP1/TAF10/MDM4/BDKRB2/WWOX/PRKAG2/BCL2L12/TAF11/TOPORS/CHEK1/CD44/MYBBP1A/ACER2/AEN/RBL2/BOP1/CNOT7/IFI16/DNA2/TAF7/GML/TAF6/ATR/CHEK2/NUPR1/RRP8/RPL11/ATM/SHISA5/WRN/PSMD10/POU4F1/SESN2/BARD1/KAT6A/MAGEA2B/RAD9A/SIRT1	97
BP	GO:0045064	T-helper 2 cell differentiation	11/4749	14/18670	4.71e-05	0.002039	0.001658	CD86/IL18/NLRP3/BATF/BCL3/BCL6/TNFSF4/IL4R/HLX/RARA/GATA3	11
BP	GO:0007265	Ras protein signal transduction	151/4749	448/18670	4.748e-05	0.002041	0.001661	IQGAP3/CDC42EP4/RASGRP2/TIAM2/GPSM2/MAPK11/KIF14/NOTCH1/PLEKHG2/FOXM1/RAB31/ARHGEF39/CDKN1A/SQSTM1/SH2B2/ITGA3/KANK2/NTRK1/RAC1/ARHGEF40/CCNA2/BCL6/CYFIP1/TIMP2/RAB33A/KSR1/SGSM3/RABL2A/RTKN/STAMBP/CSF1/ARHGEF18/PLK2/FGD2/CDC42SE1/RANGRF/MCF2L2/CDC42EP1/CYTH2/PSD4/ARHGEF12/MAPRE2/ARHGEF5/TNFAIP1/RHOG/TIAM1/RFXANK/ARHGEF2/F2RL2/RAB32/MAPKAP1/ARRB1/CDK2/RAB13/RAB3D/GRAP2/ARHGAP35/STK19/RASGRF2/STMN3/ARHGAP5/GPR35/SYNJ2BP/RAB19/PREX1/PLEKHG1/EPS8L2/ZNF304/VAV2/KSR2/STMN1/ARHGAP4/AIF1/RASA3/CFL1/LAT/PLEKHG7/ABCA1/MRAS/FLOT1/P2RY10/CCDC125/RALGDS/CDKN2A/IQSEC1/RALA/LIMK1/RASGRP4/RAB27A/PSD3/RAPGEF1/PARK7/JUN/GBF1/IFT27/RASA4/CRK/RAC2/ECT2/RAB38/MYO9B/RHOF/RABGEF1/RASAL1/RHOV/RAPGEF2/RHOU/RAB39B/RAB23/RAB2A/KCTD13/RALGPS1/F2R/LZTR1/OBSCN/RAB40B/DOK2/RHOT2/RAB40C/CYTH1/CDC42SE2/RAB15/ARF6/ARHGDIA/RAB1A/RAB34/AKAP13/BCR/RAB37/RALB/WASF2/ARHGAP1/MCF2L/C15orf62/CDC42/SHC2/WAS/NET1/RTN4R/SETDB1/NUP62/IQSEC3/GDI1/SHC1/RAB28/SPATA13/RRAS2/RAB1B/ARHGEF26/RAC3/RAB12	151
BP	GO:0042093	T-helper cell differentiation	29/4749	58/18670	4.955e-05	0.002102	0.00171	CD86/IL18/RELB/NLRP3/BATF/CD80/IRF4/BCL3/BCL6/TNFSF4/HMGB1/MTOR/FOXP3/STAT3/IL4R/SMAD7/PTGER4/LY9/HLX/RORC/IL12RB1/IL18R1/ZC3H12A/RIPK2/JAK3/RARA/ZFPM1/GATA3/IL23A	29
BP	GO:0032465	regulation of cytokinesis	40/4749	89/18670	4.956e-05	0.002102	0.00171	KIF20A/AURKB/KIF14/E2F7/E2F8/AURKA/KIF23/CIT/KIF20B/RACGAP1/CDC6/INCENP/PLK2/BRCA2/SVIL/PLK1/FSD1/PDXP/KLHL9/PKP4/KLHL21/RAB11FIP3/PRKCE/ECT2/PRC1/BCL2L1/UVRAG/PIK3C3/CDC14B/RAB11FIP4/CETN2/CENPV/PIK3R4/MAP9/CDC42/CDC25B/CXCR5/NUP62/KLHL13/TAS2R13	40
BP	GO:0045088	regulation of innate immune response	152/4749	452/18670	5.109e-05	0.002153	0.001752	IRF7/GRAMD4/RELB/HMGB3/TYRO3/IL21/PPARG/DUSP10/HCK/CLEC10A/PTPN6/IRF4/TLR8/TREX1/GRN/HEXIM1/TIRAP/TIFA/CLEC7A/PSPC1/CEACAM1/LGALS9/SFPQ/ULBP2/UNC93B1/HMGB1/PQBP1/LRP8/HSPA1A/TLR4/PTPN1/LILRA2/RAET1E/MMP12/CARD9/RSAD2/PARP14/FFAR2/FCN1/SRC/SOCS3/SEC14L1/HLA-G/PSMD8/SH2D1A/BTK/HAVCR2/UBB/TRAFD1/PSMD1/PSMD2/PAK1/TRIL/CD1D/XRCC6/UBE2N/MAP2K6/CTSB/PSMF1/IRAK3/NPLOC4/RPS27A/PAK3/PGLYRP3/LRRC14/CD300LF/RPS19/PIAS1/CYLD/ABCE1/HLA-E/RFTN1/UBA52/TLR2/A2M/FLOT1/SCRIB/MUC1/MICA/NOD2/PSMD9/TXK/TANK/IRAK1/PSMA5/ARG1/LAG3/CADM1/SUMO1/TLR6/MNDA/FPR2/CLEC4D/PSMB7/ICAM2/FBXW11/TAB1/NFKBIA/CRK/PRKCE/PSMD5/NFKBIL1/CYBA/NLRC3/IRF3/SAMHD1/BIRC3/ERAP1/PSME2/SERPING1/TNIP3/CNOT7/YTHDF3/BTRC/IFI16/CARD11/LAMP1/PIK3C3/IFNGR1/S100A8/PSMB5/RIPK2/ESR1/ULBP1/MAPKAPK2/PTPRS/COLEC12/PRKACB/PSMB4/C1QBP/TRAF6/PSMA3/PIK3R4/TSPAN6/STAT1/ANKRD17/PSMD10/PSMB1/PSMD7/PSMB3/ZCCHC3/KLRK1/CD96/PSMC5/USP17L2/FYN/PAK2/JAK1/PJA2/TRIM15/PSMD11/TRIM5	152
BP	GO:0051302	regulation of cell division	66/4749	168/18670	5.188e-05	0.002161	0.001758	KIF20A/AURKB/IL1B/KIF14/VEGFA/TXNIP/ASPM/E2F7/E2F8/AURKA/KIF23/CIT/PDGFA/KIF20B/RACGAP1/TP63/CDC6/PTCH1/INCENP/PLK2/BRCA2/SVIL/PLK1/FSD1/NAP1L2/SFN/PDXP/TGFB3/FGF9/CDK2AP2/KLHL9/PKP4/KLHL21/PRDM15/OSM/RAB11FIP3/PRKCE/ECT2/PRC1/RBL2/BCL2L1/UVRAG/PIK3C3/SIRT2/CDC14B/RAB11FIP4/YBX1/CETN2/CENPV/FGF8/PIK3R4/MAP9/EFHC1/LBH/PPBP/DLL1/THBS4/TGFB1/CDC42/CDC25B/CXCR5/PDGFB/NUP62/VEGFC/KLHL13/TAS2R13	66
BP	GO:1901991	negative regulation of mitotic cell cycle phase transition	91/4749	248/18670	5.195e-05	0.002161	0.001758	CENPF/AURKB/GTSE1/E2F7/E2F8/BUB1B/TTK/TICRR/CDK1/CDT1/CDKN1A/AURKA/KANK2/CDKN2B/KLF4/TRIP13/CDC20/CLSPN/BUB1/ZNF385A/GPNMB/CDC6/PML/E2F1/PLK2/BAX/BTN2A2/PLK1/CDC25C/CDKN2C/GADD45A/CCNB1/FBXO5/NDC80/SFN/RPL26/PSMD8/CDK2/PSMD1/PSMD2/ORC1/RFWD3/CDK2AP2/PKD2/TOPBP1/PSMF1/CCL2/ZFP36L2/FBXO31/CARM1/CNOT3/EZH2/TFDP2/MUC1/CDKN2A/PSMD9/PSMA5/MDM4/TAOK3/PSMB7/USP44/GPR132/PSMD5/MIIP/RBL2/XRCC3/ZNF830/PSME2/CNOT7/GIGYF2/PSMB5/GML/NAE1/ZFP36L1/MAD2L2/CHEK2/PSMB4/KLHL22/PSMA3/APC/ATM/PSMD10/PSMB1/PSMD7/ZNF655/PSMB3/CCND1/SYF2/PSMC5/PSMD11/DUSP1	91
BP	GO:0048285	organelle fission	151/4749	449/18670	5.381e-05	0.002224	0.001809	ESPL1/CENPF/LIF/AURKB/PKMYT1/IL1B/KIF2C/CDCA8/TPX2/KIF14/ANLN/KIFC1/ASPM/CDCA5/KIF4A/UBE2C/BUB1B/NCAPG/TTK/MKI67/CDT1/TOP2A/BIRC5/ZWINT/AURKA/KIF23/HSPA2/KIF20B/NEK2/TRIP13/CDC20/PTTG1/DLGAP5/NUSAP1/BUB1/TACC3/MYBL2/SPAG5/RACGAP1/NCAPD2/KIF18A/CDC6/RAD54L/PPP2R1A/UBE2S/SMC3/CHMP2B/MX1/SYCE3/NUF2/INCENP/SLC2A8/DHODH/FBXO43/HSPA1A/BRCA2/UBE2B/KIF11/PLK1/CDC25C/RAD51/GDAP1/PSRC1/MSX1/TDRD9/CKS2/CCNB1/CENPE/FBXO5/NUMA1/NDC80/KIF4B/DMC1/PDXP/UBB/MND1/MSTO1/BOD1/CCNE2/TERF1/PHIP/TOM1L2/TAF1L/PINK1/DIS3L2/ACOT8/HELQ/CLASP2/DSCC1/FIGNL1/TUBG2/CHTF8/NCAPH/ANAPC11/REC8/CHEK1/USP44/PIBF1/CEP192/PRC1/PHF13/STAG3/RCC1/ANAPC1/XRCC3/EME1/KLHDC3/WRAP73/SYCE2/SIRT2/CHMP1A/CDC14B/NCAPH2/NSFL1C/TUBG1/UBR2/DMRTC2/MAD2L2/PEX11A/ASZ1/ANKRD31/CHEK2/CHMP2A/INSR/KLHL22/FGF8/APC/SMC1A/CHAMP1/MAP9/PPP1R9B/SIRT7/POGZ/ATM/AAAS/MLH3/SMC5/PHF23/PLCB1/TGFB1/TOM1L1/RNF212/CDC25B/CEP97/PDGFB/NUP62/SEH1L/KLHDC8B/CENPK/RAD54B/DUSP1	151
BP	GO:0002287	alpha-beta T cell activation involved in immune response	30/4749	61/18670	5.507e-05	0.002247	0.001828	CD86/IL18/RELB/NLRP3/BATF/CD80/IRF4/BCL3/BCL6/TNFSF4/LGALS9/HMGB1/MTOR/FOXP3/STAT3/IL4R/SMAD7/PTGER4/LY9/HLX/RORC/IL12RB1/IL18R1/ZC3H12A/RIPK2/JAK3/RARA/ZFPM1/GATA3/IL23A	30
BP	GO:0002293	alpha-beta T cell differentiation involved in immune response	30/4749	61/18670	5.507e-05	0.002247	0.001828	CD86/IL18/RELB/NLRP3/BATF/CD80/IRF4/BCL3/BCL6/TNFSF4/LGALS9/HMGB1/MTOR/FOXP3/STAT3/IL4R/SMAD7/PTGER4/LY9/HLX/RORC/IL12RB1/IL18R1/ZC3H12A/RIPK2/JAK3/RARA/ZFPM1/GATA3/IL23A	30
BP	GO:0051052	regulation of DNA metabolic process	145/4749	429/18670	5.709e-05	0.002315	0.001883	TWIST1/AURKB/E2F7/E2F8/FOXM1/TICRR/CDK1/CDT1/CDKN1A/PPARG/IL10/KLF4/NEK2/RAC1/CCNA2/ESCO2/BCL6/SPI1/TNFSF4/TFRC/PARM1/CDC6/PPP2R1A/GMNN/PML/SMC3/KPNA2/HMGB1/SIRT6/MSH6/BRCA2/BAX/UBE2B/USP9X/SMG5/FOXP3/RAD51/RAD51AP1/NUDT16/SRC/PARPBP/RMI2/HCRT/DTX3L/FBXO5/DBF4/TNFAIP1/MBD2/DBF4B/TP53BP1/PIF1/CDK2/MORC2/POLQ/MAGEF1/UBE2N/RPS3/ZRANB3/UPF1/RFC2/CCT5/EYA2/PAK3/TERF1/CBX8/ZNF304/PTPRC/DSCC1/TFIP11/ERCC8/FIGNL1/TIMELESS/SUPT6H/TNKS2/PPP2CA/RECQL5/ACD/CTC1/CHTF8/AICDA/IL27RA/GNL3/RNF8/BRCC3/JUN/ERCC2/S100A11/CHEK1/IL7R/APLF/ZNF93/MAP2K4/POT1/ZNF830/ZNF91/XRCC1/MAPT-AS1/WRAP53/AUNIP/DDX11/YLPM1/DNA2/TNFSF13/ADIPOQ/IL4/KCTD13/SMG6/MAD2L2/HELB/ATR/CHEK2/RAD52/PAM16/FAM168A/SMC1A/MBD1/AXIN2/TINF2/OGG1/ATM/NUCKS1/ANKRD17/WIZ/WRN/ATG7/TGFB1/CUL4A/WAS/NMNAT1/MGMT/MAPK1/PPHLN1/HDAC10/SETDB1/PDGFB/KCNK2/GATA3/ERCC1/FBXO4/TIPIN/RNF168/TERF2/CCT3/SIRT1/DUSP1	145
BP	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	36/4749	78/18670	5.856e-05	0.002359	0.001919	TP73/CDKN1A/E2F2/PHLDA3/BCL3/PERP/ZNF385A/TP63/PML/E2F1/RRM2B/BRCA2/BAX/PMAIP1/MSX1/RPL26/UBB/CD74/DDIT4/TAF9B/MUC1/BDKRB2/WWOX/BCL2L12/TOPORS/CD44/MYBBP1A/AEN/IFI16/CHEK2/NUPR1/RRP8/RPL11/SHISA5/POU4F1/SIRT1	36
BP	GO:0044783	G1 DNA damage checkpoint	31/4749	64/18670	6.035e-05	0.002415	0.001965	GTSE1/E2F7/E2F8/CDK1/CDKN1A/AURKA/ZNF385A/PML/E2F1/PLK2/BAX/CDC25C/GADD45A/CCNB1/SFN/RPL26/CDK2/RFWD3/FBXO31/CARM1/CNOT3/TFDP2/MUC1/MDM4/RBL2/CNOT7/GIGYF2/GML/CHEK2/ATM/CCND1	31
BP	GO:0050777	negative regulation of immune response	60/4749	150/18670	6.071e-05	0.002415	0.001965	TYRO3/PPARG/DUSP10/IL10/PDCD1/PTPN6/BCL6/TREX1/GRN/TNFSF4/LGALS3/CEACAM1/LGALS9/TNF/IL2RA/FOXP3/GPX1/MMP12/CTLA4/IL4R/SMAD7/PARP14/CCR2/HMOX1/HLA-G/SAMSN1/BST2/HAVCR2/TRAFD1/TGFB3/CLEC4G/HLX/IRAK3/PGLYRP3/PTPRC/RPS19/HLA-E/DUSP22/A2M/SCRIB/MICA/IL27RA/ARG1/CRK/IL7R/NLRC3/ZC3H12A/SAMHD1/RABGEF1/SERPING1/CNOT7/YTHDF3/IFI16/FCRLB/FER/PSMB4/BCR/TGFB1/JAK3/CD96	60
BP	GO:0031145	anaphase-promoting complex-dependent catabolic process	37/4749	81/18670	6.124e-05	0.002421	0.00197	AURKB/UBE2C/BUB1B/CDK1/AURKA/CDC20/PTTG1/UBE2S/PLK1/CCNB1/FBXO5/PSMD8/CDK2/UBB/PSMD1/PSMD2/PSMF1/RPS27A/FBXO31/UBA52/PSMD9/PSMA5/ANAPC11/PSMB7/PSMD5/ANAPC1/PSME2/PSMB5/PSMB4/PSMA3/PSMD10/PSMB1/PSMD7/PSMB3/CDC16/PSMC5/PSMD11	37
BP	GO:0032743	positive regulation of interleukin-2 production	18/4749	30/18670	6.322e-05	0.002484	0.002021	IL1B/CD86/CD83/CD80/IRF4/CLEC7A/CCR2/PDE4D/PDE4B/RPS3/SPTBN1/PTPRC/CD3E/TRAF2/CARD11/RIPK2/TRAF6/GLMN	18
BP	GO:0070585	protein localization to mitochondrion	57/4749	141/18670	6.475e-05	0.002529	0.002058	TP73/BNIP3L/HK1/YWHAH/DNAJA1/YWHAE/TP63/YWHAZ/E2F1/HK2/BAX/TIMM17A/PMAIP1/MTCH2/BAG4/GDAP1/TSPO/USP36/SAE1/MOAP1/SFN/BMF/TIMM10/BAP1/PDCD5/COX18/PARL/NMT1/HPS4/BID/PINK1/TIMM22/TIMM50/ROMO1/TFDP2/GRPEL1/DDIT3/YWHAQ/RAC2/BAG3/IMMP1L/GSK3A/RHOU/UBL5/MIPEP/HSPA1L/PAM16/TOMM22/AGK/FZD5/CHCHD4/NDUFA13/TIMM9/SREBF2/BAD/RNF186/MGARP	57
BP	GO:0042092	type 2 immune response	20/4749	35/18670	6.581e-05	0.002555	0.002079	CD86/IL18/NLRP3/IL10/BATF/BCL3/BCL6/TNFSF4/IL4R/RSAD2/CCR2/CD74/HLX/NOD2/IL27RA/ARG1/IDO1/IL4/RARA/GATA3	20
BP	GO:0000082	G1/S transition of mitotic cell cycle	100/4749	279/18670	6.66e-05	0.00257	0.002091	IQGAP3/BCAT1/KIF14/GTSE1/E2F7/E2F8/CDK1/CDT1/RBBP8/CDKN1A/AURKA/CDKN3/KANK2/CDKN2B/KLF4/PTPN6/MCM4/ZNF385A/MCM5/GPNMB/CDC25A/CDC6/GMNN/PML/TYMS/MCM10/EIF4EBP1/E2F1/PLK2/BAX/BTN2A2/CDC25C/CDKN2C/GADD45A/NASP/CCNB1/MCM2/FBXO5/DBF4/SFN/RPL26/RPS6/CDC45/PIM2/CDK2/CAMK2A/ORC1/RFWD3/CDK2AP2/PKD2/CCNE2/CCL2/MCM7/DHFR/FBXO31/BID/CARM1/CDK7/PIAS1/AIF1/BRD4/CNOT3/EZH2/CDK10/TFDP2/MUC1/CDKN2A/TAF10/MDM4/POLE/MCM3/GPR132/CUL5/RBL2/RCC1/PSME2/CNOT7/RRM2/NPAT/RHOU/TMEM14B/GIGYF2/CRLF3/GML/MNAT1/CHEK2/MAX/GSPT1/BACH1/ADAMTS1/ATM/PPP6C/ANKRD17/PLCB1/CUL4A/ORC2/ZNF655/CCND1/PHF8/POLE2	100
BP	GO:0032984	protein-containing complex disassembly	115/4749	329/18670	6.83e-05	0.002613	0.002126	KIF2C/MICAL1/KIF24/DYRK3/MRPL37/MRPL28/KIF18A/CHMP2B/CAPZB/TNF/GSN/MAP1LC3A/MRPL51/MRPS36/CKAP2/SMARCB1/KLC1/MRPL22/ASPH/MICAL2/SWAP70/TMOD2/MRPL18/CAPG/ARHGEF2/MRPS5/VCP/MRPS18C/MRPS11/PDXP/DVL3/PELO/IGF1R/ADD3/SNAP29/FYCO1/SH3GL1/C12orf65/UPF1/IRAK3/CALCOCO2/STMN3/MRPS6/RPL23/SMARCA4/SPTBN1/FGF13/ABCE1/N6AMT1/DDIT4/STMN1/CLASP2/TRIOBP/TWF2/TFIP11/CFL1/DVL1/SPTAN1/MRPL20/GBA/MID1/MRPL50/CAPZA1/MRPL36/MRPS2/FRAT1/ARID1A/MRPL35/MRPL27/MRPL15/MAP1S/DNAJC6/MRPS25/TRMT112/MRPL34/TRIM54/WDR1/IST1/MRPS14/MRPL13/UVRAG/MICAL3/EIF2D/PTCD3/VILL/SNAPIN/NAPB/OGFOD1/CHMP1A/GADD45GIP1/MRPL10/SCAF4/MRPL54/LRP6/GLE1/DAP3/CHMP2A/MAP1A/INSR/DENR/GSPT1/MRPL2/APC/FZD5/MRPL39/PHF23/ZFAND1/SEMA5A/NCKAP5/KIF19/MRPL43/ADD2/CHMP3/CKAP5/MRPL48	115
BP	GO:0090199	regulation of release of cytochrome c from mitochondria	25/4749	48/18670	6.852e-05	0.002613	0.002126	PPIF/PLAUR/MLLT11/PRELID1/MMP9/NOL3/BAX/PMAIP1/GPX1/LMNA/FXN/MOAP1/BMF/CLU/PDCD5/BIK/BID/PINK1/BAK1/BCL2L1/CIDEB/TNFSF10/PAM16/PSMD10/BAD	25
BP	GO:0002819	regulation of adaptive immune response	63/4749	160/18670	7.013e-05	0.002658	0.002163	IL1B/IRF7/CD1E/IL18/NLRP3/DUSP10/IL10/IL1R1/CD80/PTPN6/BCL6/TNFSF4/TFRC/CEACAM1/HMGB1/TNF/CD1A/FOXP3/CD1C/IL4R/RSAD2/SMAD7/RIPK3/CCR2/HLA-H/HLA-G/TP53BP1/SAMSN1/BTK/CD1B/HAVCR2/CD1D/CLEC4G/HLX/PTPRC/TRPM4/HLA-E/DUSP22/SUPT6H/IL12RB1/IL27RA/ARG1/LTA/IL18R1/CD48/IL7R/APLF/ZC3H12A/TRAF2/TNFSF13/IL4/RIPK2/TNFRSF1B/MAD2L2/TRAF6/FZD5/TGFB1/WAS/JAK3/GATA3/P2RX7/IL23A/SIRT1	63
BP	GO:0002367	cytokine production involved in immune response	44/4749	102/18670	7.182e-05	0.002692	0.00219	IL1B/IL18/NR4A3/NLRP3/IL10/IL1R1/BCL6/HK1/TNFSF4/TNF/SEMA7A/TLR4/FOXP3/RSAD2/SMAD7/FFAR2/CCR2/HMOX1/HLA-G/BTK/BST2/TGFB3/CD74/TRIL/FFAR3/IRAK3/TRPM4/HLA-E/TLR2/NOD2/ARG1/IL18R1/MR1/TRAF2/IL4/TNFRSF1B/TRAF6/SPHK2/FZD5/TGFB1/JAK3/CD96/GATA3/SIRT1	44
BP	GO:0002761	regulation of myeloid leukocyte differentiation	49/4749	117/18670	7.205e-05	0.002692	0.00219	LIF/IRF7/TRIB1/FES/RASSF2/IL17A/CCR1/CEACAM1/TNF/CSF1/TLR4/PIAS3/MTOR/ESRRA/ZBTB46/PPARGC1B/TFE3/LILRB4/GNAS/CCL3/CD74/PRKCA/JUN/TOB2/CA2/CEBPB/KLF10/IL20/BGLAP/SFRP1/ADIPOQ/IL4/TYROBP/ZFP36L1/TESC/TRAF6/TNFSF11/FOS/SLC9B2/ZNF675/TGFB1/TMEM64/CUL4A/POU4F1/RARA/ZFPM1/TCTA/NME2/IL23A	49
BP	GO:0001841	neural tube formation	45/4749	105/18670	7.228e-05	0.002692	0.00219	TWIST1/SDC4/STIL/MTHFD1L/LUZP1/KIF20B/PLXNB2/PTCH1/ST14/SEMA4C/SKI/ALX1/CTHRC1/DVL3/FZD6/PTK7/KAT2A/LMO4/ARHGAP35/SPINT1/STK3/LIAS/SALL4/VASP/IFT122/CFL1/TCTN1/DVL1/MTHFD1/SCRIB/IFT172/RALA/GDF7/ARID1A/SOX11/SHROOM3/SFRP1/ADM/LRP6/PRKACB/TRAF6/MED12/TGFB1/GLMN/RARA	45
BP	GO:0007050	cell cycle arrest	87/4749	237/18670	7.368e-05	0.002728	0.00222	SKIL/GTSE1/NOTCH1/E2F7/E2F8/TP73/FOXM1/CDK1/CDKN1A/GAS2L1/AURKA/CDKN3/CDKN2B/KIF20B/ZNF385A/CDK5/SGSM3/PML/E2F1/PLK2/BAX/CDC25C/CDKN2C/GADD45A/ZBTB17/MTOR/WNT10B/VASH1/CCNB1/SFN/RPL26/CDK2/MAPK12/WHAMMP3/PKD2/ZFHX3/MAP2K6/TCF7L2/CARM1/CDK7/PRKAB2/RPL23/STRADB/CNOT3/TFDP2/MUC1/CDKN2A/TP53INP1/DDIT3/MDM4/PRKAG2/SLC38A9/PPM1G/CCNK/MYBBP1A/RBL2/CNOT7/CDC14B/GADD45GIP1/ERN1/PRNP/PRR11/CRLF3/GML/UHMK1/FZD9/LAMTOR4/CHEK2/LAMTOR2/PPP2R3B/RRP8/TBRG4/PPP1R15A/APC/PPP1R9B/UHRF2/MCPH1/WHAMM/ATM/RRAGB/TGFB1/POU4F1/CCND1/MLST8/BARD1/ILK/DUSP1	87
BP	GO:0042088	T-helper 1 type immune response	23/4749	43/18670	7.759e-05	0.002857	0.002324	EBI3/IL1B/IL18/RELB/IL18BP/IL1R1/CD80/BCL3/TNFSF4/HMGB1/TLR4/MTOR/IL4R/CCR2/HAVCR2/HLX/IL12RB1/IL27RA/IL18R1/RIPK2/TRAF6/JAK3/IL23A	23
BP	GO:0062012	regulation of small molecule metabolic process	153/4749	459/18670	7.915e-05	0.002888	0.00235	VDR/EGR1/TWIST1/PPIF/IL1B/CDK1/NR4A3/PPARG/ABCG1/PHLDA2/PDPR/SEC13/IGFBP4/TREX1/PFKFB3/ENO1/PGAM1/CEACAM1/CBFA2T3/TNF/SIRT6/PPP1CB/NUP98/PPTC7/SLC25A23/ENTPD5/PMAIP1/MTOR/LDLR/ABCD1/DNAJC30/STAT3/PMVK/FDPS/TSPO/CCNB1/SRC/SCD/SNAI1/ABCD2/PSMD8/ATCAY/FABP5/VCP/HTR2A/CRY1/PSMD1/PSMD2/CD74/PFKFB4/KAT2A/EPHX2/NUP153/IGFBP3/PSMF1/TYSND1/GUCA1C/NQO1/FOXO1/RORC/PRKAB2/PINK1/OAZ3/DDIT4/ADIPOR2/CLYBL/LMF1/BHMT/PFKFB2/SLC45A3/INSIG1/SP1/PSMD9/ATP2B4/NUP88/ADIPOR1/PSMA5/MAEA/PPP1R3E/PRKAG2/CNR1/NTSR1/C1QTNF3/PARK7/CYP27B1/PSMB7/EPM2AIP1/POM121C/OAZ2/PIBF1/PRKCE/AK4/NUP205/PSMD5/RAE1/NUP50/SQLE/GSK3A/PHKG2/PSME2/ADM/GNMT/ADIPOQ/IL4/CPT1A/PSMB5/ISCU/ARV1/POR/DGAT2/LDLRAP1/ACACB/P2RY1/PSMB4/FASN/INSR/MBTPS2/NUPR1/SPHK2/PSMA3/NUP93/OAZ1/SLC35B4/TTC39B/NUP35/AAAS/TAZ/CYP7A1/PSMD10/TGFB1/PSMB1/CLK2/PSMD7/HAS2/COX11/PSMB3/RDH10/GSTZ1/PDGFB/NUP62/PSMC5/SESN2/PTAFR/P2RX7/SEH1L/NCOR1/SREBF2/NFYB/BAD/PPP1R3B/TRIB3/PSMD11/SIRT1	153
BP	GO:0000077	DNA damage checkpoint	58/4749	145/18670	7.981e-05	0.002888	0.00235	GTSE1/E2F7/E2F8/CDK1/CDKN1A/DTL/AURKA/DOT1L/TREX1/CLSPN/ZNF385A/PML/E2F1/PLK2/BAX/PLK1/CDC25C/GADD45A/PEA15/CCNB1/SFN/RPL26/TP53BP1/CDK2/CRY1/RFWD3/FBXO31/CARM1/CNOT3/TIPRL/TFDP2/MUC1/FEM1B/MDM4/TAOK3/BRCC3/WDR76/CHEK1/RBL2/ZNF830/EME1/PRPF19/CNOT7/MDC1/CDC5L/ETAA1/GIGYF2/CDC14B/GML/ATR/CHEK2/ATM/CUL4A/CCND1/SYF2/FBXO4/TIPIN/RAD9A	58
BP	GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	58/4749	145/18670	7.981e-05	0.002888	0.00235	IL1B/CD1E/IL18/NLRP3/IL10/IL1R1/CD80/PTPN6/BCL6/TNFSF4/TFRC/CEACAM1/HMGB1/TNF/CD1A/FOXP3/CD1C/IL4R/RSAD2/SMAD7/RIPK3/CCR2/HLA-H/HLA-G/TP53BP1/BTK/CD1B/HAVCR2/CD1D/CLEC4G/HLX/PTPRC/TRPM4/HLA-E/DUSP22/SUPT6H/IL12RB1/IL27RA/ARG1/LTA/IL18R1/IL7R/APLF/ZC3H12A/TRAF2/TNFSF13/IL4/RIPK2/TNFRSF1B/MAD2L2/TRAF6/FZD5/TGFB1/WAS/JAK3/GATA3/P2RX7/IL23A	58
BP	GO:1901988	negative regulation of cell cycle phase transition	96/4749	267/18670	8.049e-05	0.002895	0.002355	CENPF/AURKB/GTSE1/E2F7/E2F8/BUB1B/TTK/TICRR/CDK1/CDT1/CDKN1A/DTL/AURKA/KANK2/CDKN2B/KLF4/TRIP13/CDC20/CLSPN/BUB1/ZNF385A/GPNMB/CDC6/PML/ATF5/E2F1/PLK2/BAX/BTN2A2/PLK1/CDC25C/CDKN2C/GADD45A/CCNB1/FBXO5/NDC80/SFN/RPL26/PSMD8/CDK2/PSMD1/PSMD2/ORC1/RFWD3/CDK2AP2/PKD2/TOPBP1/PSMF1/CCL2/ZFP36L2/FBXO31/CARM1/CNOT3/EZH2/TFDP2/MUC1/CDKN2A/PSMD9/PSMA5/MDM4/TAOK3/BRCC3/PSMB7/CHEK1/USP44/GPR132/PSMD5/MIIP/RBL2/XRCC3/ZNF830/PSME2/CNOT7/GIGYF2/PSMB5/CDC14B/GML/NAE1/ZFP36L1/MAD2L2/CHEK2/PSMB4/KLHL22/PSMA3/APC/ATM/PSMD10/PSMB1/PSMD7/ZNF655/PSMB3/CCND1/SYF2/PSMC5/PSMD11/DUSP1	96
BP	GO:0032623	interleukin-2 production	30/4749	62/18670	8.09e-05	0.002895	0.002355	IL1B/CD86/IL18/CD83/CD80/IRF4/CLEC7A/ZFP36/FOXP3/HOMER2/CARD9/CCR2/PDE4D/HAVCR2/PDE4B/RPS3/PNP/SPTBN1/PTPRC/EZR/LAG3/CD3E/TRAF2/CARD11/CD34/PRNP/RIPK2/TRAF6/GLMN/GATA3	30
BP	GO:0007088	regulation of mitotic nuclear division	64/4749	164/18670	8.431e-05	0.002981	0.002425	ESPL1/CENPF/AURKB/PKMYT1/IL1B/ANLN/CDCA5/UBE2C/BUB1B/TTK/MKI67/CDT1/AURKA/KIF20B/NEK2/TRIP13/CDC20/PTTG1/DLGAP5/NUSAP1/BUB1/TACC3/CDC6/SMC3/CHMP2B/HSPA1A/KIF11/PLK1/CDC25C/CCNB1/CENPE/FBXO5/NUMA1/NDC80/PDXP/PHIP/TOM1L2/ANAPC11/CHEK1/USP44/RCC1/ANAPC1/XRCC3/SIRT2/CHMP1A/CDC14B/NSFL1C/MAD2L2/CHMP2A/INSR/KLHL22/FGF8/APC/SMC1A/MAP9/PPP1R9B/ATM/SMC5/TGFB1/TOM1L1/CEP97/PDGFB/NUP62/DUSP1	64
BP	GO:0071158	positive regulation of cell cycle arrest	37/4749	82/18670	8.446e-05	0.002981	0.002425	GTSE1/E2F7/E2F8/TP73/CDK1/CDKN1A/AURKA/ZNF385A/PML/E2F1/PLK2/BAX/CDC25C/GADD45A/ZBTB17/CCNB1/SFN/RPL26/CDK2/PKD2/CARM1/RPL23/CNOT3/TFDP2/MUC1/MDM4/MYBBP1A/RBL2/CNOT7/CRLF3/GML/CHEK2/RRP8/UHRF2/ATM/TGFB1/POU4F1	37
BP	GO:0002683	negative regulation of immune system process	154/4749	463/18670	8.469e-05	0.002981	0.002425	NOTCH1/CD86/SDC4/GRAMD4/HMGB3/TYRO3/PPARG/DUSP10/ADORA2A/CD68/IL10/TRIB1/TSPAN32/CD80/PDCD1/PTPN6/IRF4/BCL6/TREX1/GRN/CBFB/TNFSF4/LGALS3/GPNMB/CEACAM1/LGALS9/HMGB1/TNF/ZFP36/IL2RA/CD200/TLR4/BTN2A2/LILRA2/PIAS3/TNFRSF21/FOXP3/ADTRP/LDLR/MILR1/GPX1/MMP12/CTLA4/ZBTB46/IL4R/SMAD7/PARP14/CCR2/HMOX1/GCSAM/SEC14L1/MERTK/HLA-G/HSPA9/LILRB4/SAMSN1/BTK/TIGIT/CCL3/PTGER4/BST2/HAVCR2/AXL/TRAFD1/TGFB3/CD74/CLEC4G/HLX/IRAK3/CCL2/NPLOC4/PGLYRP3/PTPRC/LRRC14/CD300LF/RPS19/EZR/TAPBPL/HLA-E/CD47/DUSP22/A2M/SCRIB/MICA/LILRB2/IL27RA/SLA2/PLCL2/THY1/ARG1/LAG3/TNFRSF13B/CNR1/TLR6/RHBDD3/MNDA/TOB2/ERBB2/NFKBIA/CRK/PIBF1/CEBPB/IL7R/NFKBIL1/IDO1/DTX1/SOX11/NLRC3/PDCD1LG2/ZC3H12A/TMEM176B/NRARP/SAMHD1/RABGEF1/SERPING1/CNOT7/YTHDF3/PADI2/DLG5/IFI16/SFRP1/GABPA/FCRLB/ADIPOQ/IL4/PRNP/FER/PTPRS/TSC22D3/TYROBP/ZFP36L1/PSMB4/C1QBP/BCR/TSPAN6/DLL1/ATM/ZNF675/HTRA1/DDT/PLCB1/TGFB1/CUL4A/GLMN/JAK3/RARA/KLRK1/CD96/ZFPM1/LDB1/TCTA/LRRC32/NME2/DUSP1	154
BP	GO:0032729	positive regulation of interferon-gamma production	31/4749	65/18670	8.745e-05	0.003061	0.002491	EBI3/IL1B/IL18/CD276/IL21/IL1R1/BCL3/TLR8/TNFSF4/CLEC7A/LGALS9/TNF/TLR4/CCR2/PDE4D/IL12RB2/HAVCR2/PDE4B/HLA-DPA1/IL12RB1/TXK/IL27RA/LTA/IL18R1/CD3E/RIPK2/HLA-DPB1/FZD5/KLRK1/ZFPM1/IL23A	31
BP	GO:0010639	negative regulation of organelle organization	134/4749	395/18670	8.872e-05	0.003089	0.002513	ESPL1/CENPF/TWIST1/LIF/AURKB/PPIF/CCNF/BUB1B/TTK/CDT1/TOP2A/NEK2/TRIP13/CDC20/PTTG1/SPI1/BUB1/PRELID1/CAPZB/FBXO43/GSN/HSPA1A/SKI/NOL3/UBE2B/PLK1/FOXP3/CKAP2/MYADM/GPX1/SMARCB1/BAG4/LMNA/TSPO/SWAP70/FXN/CCNB1/TMOD2/SRC/MCM2/FBXO5/CAPG/NDC80/ARHGEF2/SYT4/CLIP3/CORO1B/PIF1/CLU/ADD3/KAT2A/PFN2/HIP1R/NUBP1/BCOR/S1PR1/MDM1/TERF1/PICK1/TOM1L2/TMSB4Y/PINK1/SPTBN1/FGF13/CORO1A/STMN1/CLASP2/TRIOBP/TWF2/CDK10/SUPT6H/SPTAN1/TNKS2/MKKS/INSIG1/ACD/LILRB2/CTC1/ARAP1/AICDA/MID1/STYXL1/CAPZA1/ATAD2/TUBB4A/SLC25A5/CHEK1/USP44/TRIM54/KANK3/BCL2L1/BAG3/POT1/XRCC3/XRCC1/MLLT6/TMSB15A/VILL/TAF7/KDM5A/FZD9/TMEM67/SMG6/MNAT1/MAD2L2/CHMP2A/NUPR1/KLHL22/PAM16/SPHK2/CTBP1/APC/TINF2/WASF2/ATM/PSMD10/KDM4C/PHF23/ATG7/TOM1L1/WAS/ZNF451/OMA1/CEP97/CDH5/ASF1A/PHF8/USP17L2/ADD2/ERCC1/TRIM9/TERF2/SIRT1/DUSP1	134
BP	GO:0090329	regulation of DNA-dependent DNA replication	27/4749	54/18670	8.935e-05	0.003094	0.002517	E2F7/E2F8/TICRR/CDT1/BCL6/GMNN/SMC3/MSH6/BRCA2/FBXO5/DBF4/DBF4B/CDK2/ZRANB3/RFC2/TERF1/DSCC1/TIMELESS/CHTF8/AICDA/ZNF830/CHEK2/SMC1A/WIZ/ATG7/TIPIN/TERF2	27
BP	GO:0002292	T cell differentiation involved in immune response	32/4749	68/18670	9.35e-05	0.00322	0.00262	CD86/IL18/RELB/NLRP3/BATF/CD80/IRF4/BCL3/BCL6/TNFSF4/LGALS9/HMGB1/MTOR/FOXP3/STAT3/IL4R/SMAD7/PTGER4/LY9/HLX/RORC/IL12RB1/IL18R1/CD46/CLEC4D/ZC3H12A/RIPK2/JAK3/RARA/ZFPM1/GATA3/IL23A	32
BP	GO:0051983	regulation of chromosome segregation	44/4749	103/18670	9.479e-05	0.003235	0.002632	ESPL1/CENPF/AURKB/KIF2C/CDCA5/BUB1B/TTK/MKI67/CDT1/NEK2/TRIP13/CDC20/PTTG1/DLGAP5/BUB1/TACC3/SPAG5/RACGAP1/SFPQ/CDC6/PLK1/FEN1/CCNB1/RMI2/CENPE/FBXO5/NUMA1/NDC80/TTL/ANAPC11/USP44/ECT2/ANAPC1/XRCC3/DDX11/SIRT2/MAD2L2/KLHL22/APC/AXIN2/ATM/SMC5/CDC42/DUSP1	44
BP	GO:0044774	mitotic DNA integrity checkpoint	45/4749	106/18670	9.494e-05	0.003235	0.002632	GTSE1/E2F7/E2F8/TICRR/CDK1/CDKN1A/TOP2A/AURKA/CLSPN/ZNF385A/CDC6/PML/E2F1/PLK2/BAX/CDC25C/GADD45A/CCNB1/SFN/RPL26/CDK2/ORC1/RFWD3/TOPBP1/FBXO31/CARM1/CNOT3/TFDP2/MUC1/MDM4/TAOK3/RBL2/ZNF830/EME1/CNOT7/MDC1/GIGYF2/GML/NAE1/CHEK2/ATM/CCND1/SYF2/TIPIN/RAD9A	45
BP	GO:0070661	leukocyte proliferation	105/4749	298/18670	9.69e-05	0.003284	0.002672	EBI3/IL1B/CD86/SDC4/IL18/CD276/IL21/CDKN1A/CSF1R/IL10/CD80/PTPN6/BCL6/TIRAP/TNFSF4/TFRC/MZB1/LGALS3/GPNMB/LGALS9/HMGB1/CSF1/TNFRSF4/IL2RA/TLR4/BAX/BTN2A2/TNFRSF21/FOXP3/CTLA4/DOCK8/RIPK3/CCR2/HLA-G/RPS6/BTK/CLU/BST2/HAVCR2/CD74/HPRT1/CD1D/RPS3/EFNB1/CLEC4G/FLT3/SATB1/CD180/PNP/DNAJA3/HLA-DPA1/PTPRC/CORO1A/HLA-E/AIF1/LILRB2/IL12RB1/PLCL2/ARG1/CD19/TNFRSF13B/CD46/MNDA/CR2/ERBB2/IL5RA/RAC2/CD151/AZI2/CEBPB/IL7R/IDO1/HLA-DMB/SOX11/TNFSF9/PDCD1LG2/HELLS/IMPDH1/IL7/CD3E/IL13/DLG5/CCDC88B/CARD11/IL4/PRNP/RIPK2/TNFRSF1B/TYROBP/CD6/HLA-DPB1/TRAF6/TNFSF11/ATM/RAG2/SLC39A10/TGFB1/GLMN/JAK3/HHLA2/ZAP70/P2RX7/LRRC32/FYN/IL23A	105
BP	GO:0071479	cellular response to ionizing radiation	33/4749	71/18670	9.9e-05	0.003321	0.002702	EGR1/CDKN1A/TREX1/HSPA5/GADD45A/RAD51/RAD51AP1/RPL26/TP53BP1/XRCC6/NAMPT/FIGNL1/TANK/ELK1/ECT2/BCL2L1/CYBA/YAP1/IFI16/SFRP1/ATR/CHEK2/GTF2H5/ATM/NUCKS1/WRN/TGFB1/NET1/MGMT/GATA3/FBXO4/RAD9A/SIRT1	33
BP	GO:0051249	regulation of lymphocyte activation	160/4749	485/18670	9.902e-05	0.003321	0.002702	EGR3/EBI3/IL1B/CD86/SDC4/IL18/CD276/HMGB3/TYRO3/IL21/CDKN1A/NLRP3/DUSP10/ADORA2A/IL10/CD83/CD80/RAC1/PDCD1/PTPN6/IRF4/BCL6/TNFRSF18/TREX1/CBFB/SIRPA/TIRAP/TNFSF4/TFRC/MZB1/CLEC7A/LGALS3/GPNMB/CEACAM1/PRELID1/LGALS9/PRDM1/HMGB1/TNFRSF4/GSN/IL2RA/TLR4/BTN2A2/TNFRSF21/FOXP3/CTLA4/IL4R/SMAD7/DOCK8/TOX/RIPK3/CCR2/SRC/MERTK/HLA-G/TP53BP1/SIT1/LILRB4/SAMSN1/BTK/TIGIT/HAVCR2/AXL/CD74/PAK1/KAT2A/CD1D/GRAP2/RPS3/EFNB1/CLEC4G/HLX/LGALS1/PPP2R3C/CCL2/PNP/PAK3/ZFP36L2/DNAJA3/PGLYRP3/HLA-DPA1/PTPRC/CYLD/CORO1A/NFAM1/HLA-E/CD47/AIF1/DUSP22/LAT/AP3D1/SUPT6H/SART1/MICA/NOD2/LILRB2/IL12RB1/IL27RA/SLA2/THY1/ARG1/CD19/LAG3/TNFRSF13B/CD46/RHBDD3/MNDA/ERBB2/PIBF1/RAC2/CEBPB/IL7R/APLF/IDO1/DTX1/HLA-DMB/SOX11/TNFSF9/PDCD1LG2/ZC3H12A/NRARP/IL7/CD3E/IL13/DLG5/CCDC88B/SFRP1/CARD11/LAMP1/TNFSF13/IL4/PRNP/RIPK2/TNFRSF1B/TYROBP/CD6/ZFP36L1/MAD2L2/HLA-DPB1/TRAF6/VNN1/ATP11C/TNFSF11/ATM/SLC39A10/TGFB1/CDC42/GLMN/JAK3/RARA/HHLA2/KLRK1/MIR17HG/ZAP70/GATA3/LRRC32/BAD/FYN/PAK2/IL23A	160
BP	GO:0045076	regulation of interleukin-2 biosynthetic process	13/4749	19/18670	0.0001004	0.003351	0.002726	IL1B/CD86/CD80/IRF4/CLEC7A/ZFP36/FOXP3/CARD9/PTPRC/LAG3/CD3E/CARD11/GLMN	13
BP	GO:0106106	cold-induced thermogenesis	57/4749	143/18670	0.0001025	0.003384	0.002753	G0S2/VEGFA/NOTCH1/PLAC8/IL18/GADD45G/IRF4/PCTP/THRA/ACOT11/SIRT6/TLR4/ARRDC3/WNT10B/IL4R/CCR2/SCD/HCRT/PPARGC1B/TFE3/FABP5/GNAS/IGF1R/RBPJ/ATF4/PER2/MAP2K6/ACSL1/PRDM16/PRKAB2/KSR2/TLE3/CNOT3/ADIPOR2/ADIPOR1/PLCL2/DDIT3/IL18R1/ACVR2B/TSHR/EPAS1/CEBPB/ARNTL/ALMS1/IL13/GHRL/IP6K1/ADIPOQ/IL4/BSCL2/PTH2R/LNPEP/APC/ID1/PGAM5/OMA1/LPIN1	57
BP	GO:0120161	regulation of cold-induced thermogenesis	57/4749	143/18670	0.0001025	0.003384	0.002753	G0S2/VEGFA/NOTCH1/PLAC8/IL18/GADD45G/IRF4/PCTP/THRA/ACOT11/SIRT6/TLR4/ARRDC3/WNT10B/IL4R/CCR2/SCD/HCRT/PPARGC1B/TFE3/FABP5/GNAS/IGF1R/RBPJ/ATF4/PER2/MAP2K6/ACSL1/PRDM16/PRKAB2/KSR2/TLE3/CNOT3/ADIPOR2/ADIPOR1/PLCL2/DDIT3/IL18R1/ACVR2B/TSHR/EPAS1/CEBPB/ARNTL/ALMS1/IL13/GHRL/IP6K1/ADIPOQ/IL4/BSCL2/PTH2R/LNPEP/APC/ID1/PGAM5/OMA1/LPIN1	57
BP	GO:2000116	regulation of cysteine-type endopeptidase activity	87/4749	239/18670	0.0001037	0.003405	0.00277	VEGFA/GRAMD4/PPARG/NLRP3/BIRC5/CASP9/ADORA2A/MICAL1/KLF4/TTBK1/CTSH/PLAUR/PERP/RFFL/CLEC7A/HIP1/MMP9/YWHAE/TP63/LGALS9/PML/HMGB1/TNF/GSN/NOL3/BAX/TNFAIP8/PMAIP1/GPX1/ASPH/CARD9/DAP/CYFIP2/SRC/IFI6/PRDX3/P2RX1/SFN/CFLAR/ARRB1/VCP/BCL2L13/HERPUD1/PRDX5/RPS3/HIP1R/PDCD5/CCK/FAS/BID/TNFRSF10B/MAP3K5/BCAP31/KHDC1/BAK1/CTSD/CASP8AP2/PARK7/TFAP2B/BCL2L12/ACVR1C/CD44/ACER2/SIAH2/BIRC3/IFI16/DAPK1/TRAF2/DNAJB6/EIF2AK3/S100A8/ST18/F3/CIDEB/RIPK2/F2R/POR/TNFSF10/CSN2/BIRC7/CARD8/NDUFA13/MGMT/BAD/FYN/PAK2/SIRT1	87
BP	GO:1902749	regulation of cell cycle G2/M phase transition	79/4749	213/18670	0.0001042	0.003407	0.002771	CENPF/AURKB/TPX2/KIF14/GTSE1/TICRR/CDK1/DTL/AURKA/HSPA2/NEK2/CLSPN/DYRK3/CDC25A/YWHAE/CDC6/PLK4/PPP2R1A/ATF5/ODF2/PLK1/CDC25C/CENPJ/WNT10B/TUBB/CCNB1/FGFR1OP/FBXO5/DBF4B/PSMD8/CDK2/PSMD1/TUBB4B/PSMD2/ORC1/TOPBP1/PSMF1/CEP152/CEP70/BRD4/SFI1/PSMD9/PSMA5/TAOK3/BRCC3/PSMB7/TUBB4A/CHEK1/GPR132/CEP192/PSMD5/MIIP/ALMS1/ZNF830/PSME2/HAUS5/PSMB5/CDC14B/ACTR1A/NAE1/TUBG1/CETN2/PSMB4/CEP72/PSMA3/PBX1/MTA3/ATM/PSMD10/PSMB1/PSMD7/PSMB3/CDC25B/CCND1/SYF2/PSMC5/CKAP5/NINL/PSMD11	79
BP	GO:0072655	establishment of protein localization to mitochondrion	55/4749	137/18670	0.0001074	0.003492	0.002841	TP73/BNIP3L/HK1/YWHAH/DNAJA1/YWHAE/TP63/YWHAZ/E2F1/HK2/BAX/TIMM17A/PMAIP1/BAG4/GDAP1/TSPO/USP36/SAE1/MOAP1/SFN/BMF/TIMM10/BAP1/PDCD5/COX18/PARL/NMT1/HPS4/BID/PINK1/TIMM22/TIMM50/ROMO1/TFDP2/GRPEL1/DDIT3/YWHAQ/RAC2/BAG3/IMMP1L/GSK3A/RHOU/UBL5/MIPEP/HSPA1L/PAM16/TOMM22/AGK/FZD5/CHCHD4/NDUFA13/TIMM9/SREBF2/BAD/MGARP	55
BP	GO:0045444	fat cell differentiation	82/4749	223/18670	0.0001093	0.003535	0.002876	NR4A1/EGR2/PLAC8/NR4A3/PPARG/DUSP10/SH2B2/KLF4/LRG1/ZNF385A/BBS2/TGFB1I1/SYAP1/ATF5/TNF/ZFP36/E2F1/ZBTB7C/MTOR/GPX1/WNT10B/FFAR2/ASXL2/CLIP3/HTR2A/ARID5B/WWTR1/PER2/PRDM16/SLC2A4/SMAD6/FOXO1/ZFP36L2/JAG1/RORC/TCF7L2/CARM1/TMEM120B/TMEM120A/PIAS1/STK3/TRPM4/ITGA6/MKKS/INSIG1/ZADH2/BBS9/ASXL1/DDIT3/SOX8/C1QTNF3/TFAP2B/SH3PXD2B/BBS12/CEBPB/ARNTL/ZC3H12A/TPH1/ERAP1/CREBL2/RARRES2/FAM120B/SFRP1/SIRT2/ADIPOQ/BSCL2/FBXO9/ANKRD26/ZFP36L1/GRK5/PEX11A/CTBP1/PPARD/PLCB1/TGFB1/METRNL/TMEM64/CCND1/ZFPM1/GATA3/TRIB3/SIRT1	82
BP	GO:0032946	positive regulation of mononuclear cell proliferation	53/4749	131/18670	0.000112	0.003604	0.002932	EBI3/IL1B/CD86/IL18/CD276/IL21/CDKN1A/CD80/BCL6/TIRAP/TNFSF4/TFRC/LGALS9/HMGB1/CSF1/TNFRSF4/IL2RA/TLR4/FOXP3/CCR2/HAVCR2/CD74/CD1D/RPS3/EFNB1/PNP/DNAJA3/HLA-DPA1/PTPRC/CORO1A/HLA-E/AIF1/LILRB2/IL12RB1/CD46/HLA-DMB/TNFSF9/PDCD1LG2/IL7/CD3E/IL13/CCDC88B/CARD11/IL4/RIPK2/CD6/HLA-DPB1/TRAF6/SLC39A10/JAK3/HHLA2/ZAP70/IL23A	53
BP	GO:0046394	carboxylic acid biosynthetic process	153/4749	462/18670	0.000113	0.003619	0.002944	BCAT1/IL1B/HSD3B7/MTHFD1L/TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/CH25H/PTGIS/ALOX5AP/ENO1/CYP7B1/PGAM1/CEACAM1/PFKP/ACSM3/SERINC3/ACOT11/GAMT/GPI/CBFA2T3/SIRT6/RIMKLB/HK2/FADS3/NUP98/ENTPD5/TECR/SDS/ABCD1/STAT3/CARNS1/MYO5A/MECR/SCD/FA2H/ABCD2/GGT1/GLS2/PGM2L1/PKM/ABAT/FABP5/ALDOC/SLC27A2/OGDH/HTR2A/MCAT/CD74/MTHFS/PFKFB4/GPT/PER2/ASNS/EPHX2/NUP153/SLC35D1/ACOX2/CTH/TECRL/DHFR/PRKAB2/HSD17B8/ACOT8/LIAS/DDIT4/MRI1/ADIPOR2/GALK1/MTHFD1/BHMT/PFKFB2/ALOX5/SLC45A3/INSIG1/GGTLC2/ATP2B4/NUP88/ADIPOR1/ENO3/PRKAG2/GPX4/TBXAS1/NAGS/AMACR/PARK7/SEPHS1/ELOVL7/NAT8L/MTRR/MTAP/POM121C/DSEL/PIBF1/PTGES2/NUP205/RAE1/ELOVL1/IDO1/DPYD/NUP50/PSPH/GLUD1/HAS3/ASAH2/ABHD1/ALDOA/ADIPOQ/ENOPH1/OXSM/ASAH2B/MGST2/ACACB/GGT7/AASDHPPT/ACSS1/FASN/INSR/MTR/NUPR1/OSBPL7/GPT2/CYP2D6/NUP93/PLOD3/MGST3/HPGD/PFKL/ALDOB/NUP35/PLA2G5/PECR/AAAS/CYP7A1/TGFB1/HAS2/RDH10/PDGFB/NUP62/AKR1A1/P2RX7/SEH1L/NCOR1/ASNSD1/DECR2/OSBPL9/BHMT2/TRIB3/SIRT1	153
BP	GO:0051188	cofactor biosynthetic process	113/4749	326/18670	0.000116	0.003698	0.003008	MTHFD1L/TPI1/CHAC1/PDPR/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/PTGIS/ENO1/PGAM1/PFKP/GPI/CBFA2T3/SIRT6/HK2/SLC25A1/NUP98/CYBB/CPOX/FDXR/PPTC7/CTNS/ENTPD5/TPK1/TECR/CHAC2/STAT3/TSPO/FXN/MMAB/SCD/GGT1/PGM2L1/PKM/ALDOC/OGDH/HTR2A/PDHB/IBA57/PPT1/MTHFS/PFKFB4/NUP153/ACSL1/PDHX/DHFR/OPLAH/HSD17B8/NAMPT/LIAS/DDIT4/NADK/GALK1/MTHFD1/PARP16/PFKFB2/DLAT/NUP88/ENO3/PRKAG2/ELOVL7/RSAD1/MMACHC/POM121C/NUP205/RAE1/ELOVL1/IDO1/ZNF205/MOCS1/BDH2/CYBA/NUP50/ACSL4/NDUFA9/METTL16/ALDOA/PANK4/PPOX/MGST2/COQ10A/ACACB/GCLC/RNLS/GGT7/ACSS1/FASN/INSR/NUPR1/NUP93/PFKL/NFS1/ALDOB/NUP35/SPR/GSS/PANK1/AAAS/MPC1/NMNAT1/GSTZ1/NMNAT3/NUP62/SLC25A16/AKR1A1/P2RX7/SEH1L/NCOR1/FYN/ASPDH	113
BP	GO:0090559	regulation of membrane permeability	38/4749	86/18670	0.0001181	0.003744	0.003046	PPIF/TP73/BNIP3L/YWHAH/YWHAE/TP63/YWHAZ/E2F1/HK2/HSPA1A/NOL3/BAX/TJP2/PMAIP1/MTOR/NAIF1/CNP/STAT3/MOAP1/SFN/BMF/CAMK2A/HIP1R/EYA2/NMT1/BID/TFDP2/BAK1/YWHAQ/SLC25A5/STPG1/ZNF205/BCL2L1/GSK3A/RHOT2/FZD9/SPG7/BAD	38
BP	GO:0030330	DNA damage response, signal transduction by p53 class mediator	45/4749	107/18670	0.0001239	0.003909	0.00318	TWIST1/GTSE1/E2F7/E2F8/FOXM1/CDK1/CDKN1A/AURKA/BATF/BCL3/SPRED2/DYRK3/ZNF385A/PML/E2F1/PLK2/BRCA2/BAX/CDC25C/GADD45A/PMAIP1/MSX1/CCNB1/SNAI1/SFN/RPL26/CDK2/CD74/CARM1/NDRG1/CNOT3/TFDP2/MUC1/MDM4/CD44/ACER2/RBL2/CNOT7/GML/ATR/CHEK2/ATM/PSMD10/SESN2/SIRT1	45
BP	GO:0016053	organic acid biosynthetic process	153/4749	463/18670	0.000127	0.003987	0.003243	BCAT1/IL1B/HSD3B7/MTHFD1L/TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/CH25H/PTGIS/ALOX5AP/ENO1/CYP7B1/PGAM1/CEACAM1/PFKP/ACSM3/SERINC3/ACOT11/GAMT/GPI/CBFA2T3/SIRT6/RIMKLB/HK2/FADS3/NUP98/ENTPD5/TECR/SDS/ABCD1/STAT3/CARNS1/MYO5A/MECR/SCD/FA2H/ABCD2/GGT1/GLS2/PGM2L1/PKM/ABAT/FABP5/ALDOC/SLC27A2/OGDH/HTR2A/MCAT/CD74/MTHFS/PFKFB4/GPT/PER2/ASNS/EPHX2/NUP153/SLC35D1/ACOX2/CTH/TECRL/DHFR/PRKAB2/HSD17B8/ACOT8/LIAS/DDIT4/MRI1/ADIPOR2/GALK1/MTHFD1/BHMT/PFKFB2/ALOX5/SLC45A3/INSIG1/GGTLC2/ATP2B4/NUP88/ADIPOR1/ENO3/PRKAG2/GPX4/TBXAS1/NAGS/AMACR/PARK7/SEPHS1/ELOVL7/NAT8L/MTRR/MTAP/POM121C/DSEL/PIBF1/PTGES2/NUP205/RAE1/ELOVL1/IDO1/DPYD/NUP50/PSPH/GLUD1/HAS3/ASAH2/ABHD1/ALDOA/ADIPOQ/ENOPH1/OXSM/ASAH2B/MGST2/ACACB/GGT7/AASDHPPT/ACSS1/FASN/INSR/MTR/NUPR1/OSBPL7/GPT2/CYP2D6/NUP93/PLOD3/MGST3/HPGD/PFKL/ALDOB/NUP35/PLA2G5/PECR/AAAS/CYP7A1/TGFB1/HAS2/RDH10/PDGFB/NUP62/AKR1A1/P2RX7/SEH1L/NCOR1/ASNSD1/DECR2/OSBPL9/BHMT2/TRIB3/SIRT1	153
BP	GO:0009166	nucleotide catabolic process	69/4749	182/18670	0.0001297	0.004055	0.003299	TPI1/DCTPP1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/PDE4A/GPI/CBFA2T3/SIRT6/HK2/NUP98/ENTPD5/GPX1/ABCD1/CNP/STAT3/NUDT16/NUDT1/PGM2L1/PKM/PDE4D/ALDOC/VCP/OGDH/HTR2A/PDE4B/PFKFB4/HPRT1/NUP153/PNP/DDIT4/GALK1/PFKFB2/NUP88/ENO3/PRKAG2/POM121C/NUP205/RAE1/NUDT17/NUP50/SAMHD1/ENTPD4/NUDT3/ALDOA/AMPD3/NT5E/PDE7B/INSR/NUPR1/NUP93/NEIL1/PFKL/ALDOB/NUP35/OGG1/AAAS/NT5C2/NUP62/P2RX7/SEH1L/NCOR1/ASPDH	69
BP	GO:0071347	cellular response to interleukin-1	68/4749	179/18670	0.0001348	0.004191	0.003409	EGR1/IL1B/MAPK11/ICAM1/SQSTM1/KLF2/IL1R1/CCL20/CCL3L3/IL17A/IL1RN/PTGIS/SIRPA/CCL22/GBP2/HYAL3/IL1R2/PSMD8/CCL3/UBB/PSMD1/PSMD2/UBE2N/PSMF1/UPF1/IRAK3/CCL2/RPS27A/TOLLIP/CCL17/CD47/CCL18/UBA52/NOD2/PSMD9/TANK/IRAK1/PSMA5/PSMB7/FBXW11/TAB1/NFKBIA/PSMD5/CEBPB/MAP3K3/ZC3H12A/PSME2/BTRC/SFRP1/ST18/PSMB5/RIPK2/PSMB4/TRAF6/CCL23/PSMA3/CCL7/ZNF675/PSMD10/PLCB1/CCL15/PSMB1/PSMD7/HAS2/PSMB3/PSMC5/TFPI/PSMD11	68
BP	GO:0090073	positive regulation of protein homodimerization activity	9/4749	11/18670	0.0001452	0.00444	0.003612	TIRAP/LGALS3/SYAP1/TRAF4/PARK7/STPG1/TRAF2/ARF6/CRBN	9
BP	GO:0006090	pyruvate metabolic process	60/4749	154/18670	0.0001455	0.00444	0.003612	SLC16A3/NR4A3/TPI1/PDPR/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/SLC16A1/ENO1/PGAM1/PFKP/GPI/CBFA2T3/SIRT6/HK2/NUP98/ENTPD5/SDS/STAT3/LDHAL6B/PGM2L1/PKM/ALDOC/OGDH/HTR2A/PDHB/PFKFB4/NUP153/PDHX/DDIT4/GALK1/PFKFB2/DLAT/NUP88/ENO3/PRKAG2/VDAC1/POM121C/NUP205/RAE1/NUP50/BSG/ALDOA/ME3/INSR/NUPR1/NUP93/PFKL/ALDOB/NUP35/AAAS/MPC1/GSTZ1/NUP62/P2RX7/SEH1L/NCOR1	60
BP	GO:0031663	lipopolysaccharide-mediated signaling pathway	28/4749	58/18670	0.0001455	0.00444	0.003612	IL1B/IL18/TRIB1/HCK/TNF/TLR4/LILRA2/CCL3/CD180/CCL2/SIGIRR/PRKCA/TLR2/IRAK1/NFKBIA/DEFB114/PRKCE/NFKBIL1/IRF3/LACRT/RIPK2/CD6/TRAF6/CARD8/TGFB1/MAPK1/PTAFR/TRIM5	28
BP	GO:0046605	regulation of centrosome cycle	28/4749	58/18670	0.0001455	0.00444	0.003612	CCNF/STIL/AURKA/NEK2/PLK4/CHMP2B/ATF5/PLK2/KIF11/CENPJ/KAT2A/POC1A/NUBP1/MDM1/CHORDC1/CHEK1/MARK4/C10orf90/ALMS1/XRCC3/CHMP1A/NSFL1C/TMEM67/CHMP2A/MAP9/MCPH1/NUP62/CHMP3	28
BP	GO:0045930	negative regulation of mitotic cell cycle	116/4749	338/18670	0.0001507	0.004577	0.003723	CENPF/AURKB/GTSE1/E2F7/E2F8/BUB1B/TTK/TICRR/CDK1/CDT1/CDKN1A/TOP2A/ZWINT/AURKA/IL10/KANK2/CDKN2B/KLF4/TRIP13/CDC20/PTTG1/BCL6/CLSPN/BUB1/ZNF385A/TIMP2/GPNMB/CDC6/PML/TNF/E2F1/PLK2/BAX/BTN2A2/PLK1/CDC25C/CDKN2C/GADD45A/CCNB1/FBXO5/NDC80/SFN/RPL26/PSMD8/RPS6/CDK2/PSMD1/PSMD2/ORC1/RFWD3/CDK2AP2/PKD2/TOPBP1/PSMF1/CCL2/ZFP36L2/FBXO31/CARM1/TOM1L2/CNOT3/EZH2/TFDP2/SCRIB/MUC1/CDKN2A/PSMD9/PSMA5/MDM4/TAOK3/PSMB7/CHEK1/USP44/GPR132/PSMD5/MIIP/RBL2/BCL2L1/XRCC3/ZNF830/PSME2/EME1/CNOT7/MDC1/GIGYF2/HECA/PSMB5/CDC14B/GADD45GIP1/GML/NAE1/ZFP36L1/MAD2L2/CHEK2/PSMB4/KLHL22/PSMA3/TRIM35/APC/MCPH1/ATM/PSMD10/TGFB1/TOM1L1/PSMB1/PSMD7/ZNF655/PSMB3/CCND1/SYF2/PSMC5/BTG3/USP17L2/TIPIN/RAD9A/PSMD11/DUSP1	116
BP	GO:0015949	nucleobase-containing small molecule interconversion	17/4749	29/18670	0.0001515	0.004579	0.003725	TYMS/RRM2B/DTYMK/AK5/RRM1/NME4/DCTD/NME3/AK4/RRM2/GUK1/AK1/CMPK1/CTPS2/AK2/NUDT13/NME2	17
BP	GO:0006275	regulation of DNA replication	45/4749	108/18670	0.0001605	0.004791	0.003898	E2F7/E2F8/TICRR/CDK1/CDT1/RAC1/CCNA2/ESCO2/BCL6/CDC6/PPP2R1A/GMNN/SMC3/MSH6/BRCA2/HCRT/FBXO5/DBF4/TNFAIP1/DBF4B/CDK2/ZRANB3/RFC2/TERF1/DSCC1/TIMELESS/PPP2CA/CTC1/CHTF8/AICDA/JUN/S100A11/MAP2K4/ZNF830/DNA2/KCTD13/ATR/CHEK2/SMC1A/NUCKS1/ANKRD17/WIZ/ATG7/TIPIN/TERF2	45
BP	GO:0001843	neural tube closure	39/4749	90/18670	0.0001606	0.004791	0.003898	TWIST1/SDC4/STIL/MTHFD1L/KIF20B/PLXNB2/PTCH1/ST14/SEMA4C/SKI/ALX1/CTHRC1/DVL3/FZD6/PTK7/KAT2A/LMO4/ARHGAP35/SPINT1/LIAS/SALL4/VASP/IFT122/DVL1/MTHFD1/SCRIB/IFT172/RALA/ARID1A/SHROOM3/SFRP1/ADM/LRP6/PRKACB/TRAF6/MED12/TGFB1/GLMN/RARA	39
BP	GO:0010389	regulation of G2/M transition of mitotic cell cycle	73/4749	196/18670	0.0001608	0.004791	0.003898	CENPF/AURKB/TPX2/KIF14/TICRR/CDK1/DTL/AURKA/HSPA2/NEK2/CLSPN/CDC25A/YWHAE/CDC6/PLK4/PPP2R1A/ODF2/PLK1/CDC25C/CENPJ/WNT10B/TUBB/CCNB1/FGFR1OP/FBXO5/DBF4B/PSMD8/CDK2/PSMD1/TUBB4B/PSMD2/ORC1/TOPBP1/PSMF1/CEP152/CEP70/BRD4/SFI1/PSMD9/PSMA5/TAOK3/PSMB7/TUBB4A/GPR132/CEP192/PSMD5/MIIP/ALMS1/ZNF830/PSME2/HAUS5/PSMB5/ACTR1A/NAE1/TUBG1/CETN2/PSMB4/CEP72/PSMA3/PBX1/MTA3/ATM/PSMD10/PSMB1/PSMD7/PSMB3/CDC25B/CCND1/SYF2/PSMC5/CKAP5/NINL/PSMD11	73
BP	GO:0031098	stress-activated protein kinase signaling cascade	109/4749	315/18670	0.0001636	0.004851	0.003947	IL1B/PBK/MAPK11/VEGFA/FOXM1/DUSP10/GADD45G/TRIB1/RASSF2/EPHB1/IL1RN/SIRPA/TIRAP/DNAJA1/LGALS9/SEMA4C/HMGB1/TNF/ZFP36/FGD2/TLR4/PTPN1/GADD45A/CARD9/NBR1/PDCD4/MAP3K6/ARHGEF5/TIAM1/MAP2K3/PAK4/SDCBP/MAP3K2/PTGER4/DVL3/UBB/IGF1R/PAK1/UBE2N/RPS3/MAP2K6/FKTN/RPS27A/FOXO1/PAK3/TNFRSF19/CASR/FAS/MAP3K5/PINK1/EZR/CYLD/STRADB/STK3/NRK/UBA52/DUSP22/NOD2/TRAF4/MAP3K11/IRAK1/MID1/DTNBP1/IL26/TAOK3/WNT7A/TLR6/FZD8/RAPGEF1/STK25/SH2D3A/FBXW11/TAB1/SH2D3C/PHLPP1/MAP3K3/ZC3H12A/MINK1/NEK1/MAP2K4/FLT4/BTRC/EMC10/SFRP1/TRAF2/MAP4K1/ERN1/RIPK2/MAPKAPK2/IL36A/ZFP36L1/AIDA/TRAF6/BIRC7/MIR181D/TNFSF11/EDAR/FZD5/NCF1/ZNF675/MAP3K9/PLCB1/MAPK1/NCOR1/PRDX1/PAK2/IL37/PJA2/DUSP1	109
BP	GO:0002700	regulation of production of molecular mediator of immune response	55/4749	139/18670	0.0001685	0.004928	0.004009	IL1B/IL18/NR4A3/NLRP3/IL10/IL1R1/BCL6/HK1/TREX1/TNFSF4/TFRC/MZB1/GPI/TNF/TNFRSF4/SEMA7A/TLR4/FOXP3/IL4R/RSAD2/SMAD7/FFAR2/CCR2/HMOX1/HLA-G/TP53BP1/BTK/BST2/TGFB3/CD74/TRIL/FFAR3/IRAK3/PTPRC/TRPM4/HLA-E/SUPT6H/NOD2/IL27RA/ARG1/IL18R1/APLF/IL13/TRAF2/TNFSF13/IL4/TNFRSF1B/MAD2L2/KLK5/TRAF6/FZD5/TGFB1/JAK3/CD96/GATA3	55
BP	GO:0045580	regulation of T cell differentiation	55/4749	139/18670	0.0001685	0.004928	0.004009	EGR3/CD86/IL18/NLRP3/DUSP10/CD83/CD80/IRF4/BCL6/TNFRSF18/CBFB/TNFSF4/PRELID1/LGALS9/PRDM1/HMGB1/IL2RA/BTN2A2/FOXP3/CTLA4/IL4R/SMAD7/CCR2/HLA-G/LILRB4/CD74/KAT2A/HLX/PNP/PTPRC/CYLD/AP3D1/SART1/LILRB2/IL12RB1/LAG3/CD46/ERBB2/IL7R/DTX1/TNFSF9/ZC3H12A/NRARP/IL7/CARD11/IL4/RIPK2/VNN1/TGFB1/JAK3/RARA/ZAP70/GATA3/BAD/IL23A	55
BP	GO:0070665	positive regulation of leukocyte proliferation	55/4749	139/18670	0.0001685	0.004928	0.004009	EBI3/IL1B/CD86/IL18/CD276/IL21/CDKN1A/CD80/BCL6/TIRAP/TNFSF4/TFRC/LGALS9/HMGB1/CSF1/TNFRSF4/IL2RA/TLR4/FOXP3/CCR2/BST2/HAVCR2/CD74/CD1D/RPS3/EFNB1/PNP/DNAJA3/HLA-DPA1/PTPRC/CORO1A/HLA-E/AIF1/LILRB2/IL12RB1/CD46/IL5RA/HLA-DMB/TNFSF9/PDCD1LG2/IL7/CD3E/IL13/CCDC88B/CARD11/IL4/RIPK2/CD6/HLA-DPB1/TRAF6/SLC39A10/JAK3/HHLA2/ZAP70/IL23A	55
BP	GO:1901293	nucleoside phosphate biosynthetic process	131/4749	390/18670	0.0001722	0.005005	0.004072	TPI1/PDPR/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/PTGIS/ENO1/PGAM1/PFKP/TYMS/GPI/CBFA2T3/SIRT6/DHODH/HK2/AGPAT3/TK1/SLC25A1/RRM2B/NUP98/ENTPD5/AGPAT2/TECR/CMPK2/DNAJC30/STAT3/ERH/ADCY4/DTYMK/PFAS/SCD/PGM2L1/PKM/AK5/ALDOC/VCP/OGDH/HTR2A/RRM1/PDHB/PPT1/PFKFB4/HPRT1/ADCY6/NUP153/ACSL1/PDHX/AK3/GUCA1C/PNP/LHPP/NME4/PINK1/HSD17B8/NAMPT/UPRT/DDIT4/NADK/SLC35B2/DCTD/VPS9D1/PRPSAP2/GALK1/MTHFD1/PARP16/PFKFB2/DLAT/NUP88/ENO3/AMPD2/PRKAG2/NME3/ELOVL7/POM121C/AK4/NUP205/RAE1/ELOVL1/IDO1/ADCY3/NUP50/APRT/IMPDH1/ACSL4/RRM2/ALDOA/GUK1/AMPD3/IL4/PANK4/ACACB/TAMM41/RNLS/LCLAT1/AK1/CMPK1/CTPS2/ACSS1/UCK2/FASN/INSR/NUPR1/ADCY9/SPHK2/PRPS1/NUP93/PFKL/PAPSS2/ALDOB/NUP35/NME9/PANK1/AAAS/TAZ/AK2/TGFB1/MPC1/GPAT2/NMNAT1/MAPK1/GSTZ1/NMNAT3/NUP62/P2RX7/SEH1L/NCOR1/NME2/ASPDH	131
BP	GO:0042094	interleukin-2 biosynthetic process	14/4749	22/18670	0.0001742	0.005005	0.004072	IL1B/CD86/IL18/CD80/IRF4/CLEC7A/ZFP36/FOXP3/CARD9/PTPRC/LAG3/CD3E/CARD11/GLMN	14
BP	GO:0043496	regulation of protein homodimerization activity	14/4749	22/18670	0.0001742	0.005005	0.004072	TIRAP/LGALS3/SYAP1/HSPA5/BAX/BAK1/TRAF4/PARK7/STPG1/TRAF2/AIDA/ARF6/ID1/CRBN	14
BP	GO:1904666	regulation of ubiquitin protein ligase activity	14/4749	22/18670	0.0001742	0.005005	0.004072	UBE2C/CDC20/GORASP1/UBE2S/PLK1/RPL5/FBXO5/RPL23/USP44/BAG2/CDC14B/MAD2L2/RAB1A/RPL11	14
BP	GO:0050671	positive regulation of lymphocyte proliferation	52/4749	130/18670	0.0001818	0.005179	0.004213	EBI3/IL1B/CD86/IL18/CD276/IL21/CDKN1A/CD80/BCL6/TIRAP/TNFSF4/TFRC/LGALS9/HMGB1/TNFRSF4/IL2RA/TLR4/FOXP3/CCR2/HAVCR2/CD74/CD1D/RPS3/EFNB1/PNP/DNAJA3/HLA-DPA1/PTPRC/CORO1A/HLA-E/AIF1/LILRB2/IL12RB1/CD46/HLA-DMB/TNFSF9/PDCD1LG2/IL7/CD3E/IL13/CCDC88B/CARD11/IL4/RIPK2/CD6/HLA-DPB1/TRAF6/SLC39A10/JAK3/HHLA2/ZAP70/IL23A	52
BP	GO:1901987	regulation of cell cycle phase transition	157/4749	480/18670	0.0001819	0.005179	0.004213	ESPL1/CENPF/AURKB/TPX2/KIF14/ANLN/GTSE1/E2F7/E2F8/CDCA5/UBE2C/BUB1B/FAM83D/TTK/TICRR/CDK1/CDT1/CDKN1A/DTL/AURKA/HSPA2/KANK2/CDKN2B/KLF4/NEK2/PTPN6/TRIP13/CDC20/DLGAP5/CLSPN/BUB1/DYRK3/ZNF385A/GPNMB/CDC25A/YWHAE/UBD/CDC6/PLK4/PPP2R1A/PML/ATF5/E2F1/PLK2/ODF2/BAX/BTN2A2/PLK1/CDC25C/CDKN2C/GADD45A/CENPJ/WNT10B/TUBB/CCNB1/CENPE/FGFR1OP/FBXO5/DBF4/NDC80/SFN/RPL26/DBF4B/PSMD8/CDC45/CDK2/PSMD1/TUBB4B/PSMD2/ORC1/RFWD3/CDK2AP2/PKD2/TOPBP1/PSMF1/CCL2/ZFP36L2/FBXO31/CEP152/BID/CARM1/CEP70/AIF1/BRD4/CNOT3/EZH2/CDK10/SFI1/TFDP2/MUC1/CDKN2A/PSMD9/ATP2B4/PSMA5/MDM4/TAOK3/ANAPC11/BRCC3/PSMB7/ERCC2/TUBB4A/CHEK1/USP44/GPR132/CEP192/PSMD5/MIIP/RBL2/ALMS1/ANAPC1/XRCC3/ZNF830/PSME2/CNOT7/HAUS5/BTRC/TMEM14B/SIRT2/GIGYF2/PSMB5/CDC14B/ACTR1A/GML/NAE1/TUBG1/ZFP36L1/MAD2L2/CETN2/CHEK2/PSMB4/CEP72/KLHL22/PSMA3/APC/PBX1/PPP1R9B/MTA3/ADAMTS1/ATM/ANKRD17/PSMD10/PLCB1/TGFB1/CUL4A/PSMB1/PSMD7/ZNF655/PSMB3/CDC25B/CCND1/SYF2/CDC16/PSMC5/CKAP5/NINL/PSMD11/DUSP1	157
BP	GO:0051222	positive regulation of protein transport	139/4749	418/18670	0.0001849	0.005241	0.004264	TWIST1/IL1B/MAPK11/GTSE1/NLRP3/ADORA2A/CSF1R/IL10/ABCG1/KIF20B/RAC1/TLR8/IL17A/GAPDH/HK1/TNFSF4/CAMK1/CDK5/YWHAE/LGALS9/RBM22/GPI/MYH10/HMGB1/TNF/TNFRSF4/BLK/TLR4/LILRA2/MMP12/IL4R/FFAR2/FRMD4A/SORL1/USP36/FCN1/SRC/SAE1/TENM1/SEC16A/ARHGEF5/B3GAT3/SFN/ABAT/ARRB1/CCL3/ATP13A2/PTGER4/HAVCR2/C2CD2L/SRI/CD33/TGFB3/PAK1/BAP1/PDCD5/CASR/HPS4/TCF7L2/PINK1/SPTBN1/EZR/BCAP31/TRPM4/NADK/HLA-E/AIF1/OXCT1/TLR2/KCNN4/PFKFB2/CD58/NOD2/PSMD9/LRP1/TMEM30A/IL26/OSM/CADM1/SIRT3/C1QTNF3/CHP1/EMD/EFCAB7/ERBB2/IL17RC/OAZ2/PRKCE/RAC2/ECT2/EDEM2/IRF3/GLUD1/ZC3H12A/BAG3/PAEP/LILRA5/GSK3A/IL13/RHOU/UBL5/CD2AP/IFNGR1/GHRL/CD34/PRNP/RIPK2/MYOM1/F2R/SERP1/DOC2B/HSPA1L/CLEC5A/ARF6/OAZ1/CARD8/PARD6A/FZD5/STOM/PPARD/FFAR1/ZFAND1/RUFY3/TGFB1/BCAS3/CNST/GLMN/MAPK1/ADAM9/TRIM16/GATA3/PDX1/P2RX7/GIPR/SREBF2/SYBU/VEGFC/BAD/FYN	139
BP	GO:0071276	cellular response to cadmium ion	20/4749	37/18670	0.0001869	0.005276	0.004292	MMP9/GSN/CYBB/MT1E/MT2A/HMOX1/MT1X/MT1H/SUMO1/MT1G/JUN/PPP5C/MT1A/MT1B/MT1M/NCF1/FOS/OGG1/MAPK1/MT1F	20
BP	GO:0043618	regulation of transcription from RNA polymerase II promoter in response to stress	49/4749	121/18670	0.0001939	0.005441	0.004426	EGR1/VEGFA/NOTCH1/KLF2/ATF3/HSPA5/HSPA1A/HMOX1/LIMD1/PSMD8/UBB/PSMD1/PSMD2/RBPJ/ATF4/PSMF1/RPS27A/HSF2/UBA52/MUC1/HSF4/PSMD9/PSMA5/DDIT3/JUN/PSMB7/CHEK1/HIF3A/EPAS1/PSMD5/CITED2/CEBPB/RBL2/BAG3/PSME2/SIRT2/PSMB5/PSMB4/MBTPS2/PSMA3/HIF1AN/BACH1/PSMD10/PSMB1/PSMD7/PSMB3/PSMC5/SESN2/PSMD11	49
BP	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	27/4749	56/18670	0.0001953	0.005441	0.004426	GTSE1/E2F7/E2F8/CDK1/CDKN1A/AURKA/ZNF385A/PML/E2F1/PLK2/BAX/CDC25C/GADD45A/CCNB1/SFN/RPL26/CDK2/CARM1/CNOT3/TFDP2/MUC1/MDM4/RBL2/CNOT7/GML/CHEK2/ATM	27
BP	GO:0090307	mitotic spindle assembly	27/4749	56/18670	0.0001953	0.005441	0.004426	AURKB/TPX2/KIFC1/KIF4A/BIRC5/KIF23/NEK2/CDC20/MYBL2/RACGAP1/SMC3/CHMP2B/HSPA1A/KIF11/PLK1/KIF4B/MSTO1/PIBF1/CEP192/WRAP73/CHMP1A/CHEK2/CHMP2A/SMC1A/MAP9/AAAS/CEP97	27
BP	GO:2001251	negative regulation of chromosome organization	57/4749	146/18670	0.0001973	0.005472	0.004452	ESPL1/CENPF/TWIST1/AURKB/BUB1B/TTK/CDT1/TOP2A/TRIP13/CDC20/PTTG1/SPI1/BUB1/SKI/UBE2B/PLK1/FOXP3/SMARCB1/CCNB1/SRC/MCM2/FBXO5/NDC80/PIF1/BCOR/TERF1/SUPT6H/TNKS2/ACD/CTC1/AICDA/ATAD2/USP44/POT1/XRCC3/XRCC1/MLLT6/TAF7/KDM5A/SMG6/MNAT1/MAD2L2/KLHL22/SPHK2/CTBP1/APC/TINF2/ATM/KDM4C/ZNF451/ASF1A/PHF8/USP17L2/ERCC1/TERF2/SIRT1/DUSP1	57
BP	GO:0043405	regulation of MAP kinase activity	115/4749	337/18670	0.0002076	0.005732	0.004663	IQGAP3/IL1B/MAPK11/VEGFA/TP73/CDK1/DUSP10/GADD45G/DUSP4/FPR1/TRIB1/NTRK1/PDGFA/PTPN6/DUSP6/SPRED2/DNAJA1/KSR1/PPP2R1A/TNF/ADRA2B/FGD2/TLR4/PTPN1/GADD45A/PEA15/TRAF7/PDCD4/SORL1/SRC/TENM1/MAP3K6/ARHGEF5/TIAM1/MAP2K3/DUSP5/ARRB1/HTR2A/MAP3K2/NTRK3/DVL3/UBB/IGF1R/TGFB3/CD74/PAK1/UBE2N/RPS3/MAP2K6/PIK3R5/FLT3/IRAK3/RPS27A/PAK3/DUSP16/MAP3K5/PTPRC/ITGA1/EZH2/NRK/UBA52/PPP2CA/NOD2/MAP3K11/GBA/IRAK1/DTNBP1/HGS/FLT1/TAOK3/TLR6/FZD8/RAPGEF1/ERBB2/TAB1/CRK/DEFB114/MAP3K3/MAP2K4/DUSP18/SFRP1/TRAF2/GHRL/ADIPOQ/MAP4K1/ERN1/RIPK2/F2R/MAPKAPK2/AIDA/STK38/LAMTOR2/INSR/TRAF6/BIRC7/DUSP14/AKAP13/TNFSF11/FZD5/NTF3/ZNF675/MAP3K9/TGFB1/SHC2/UCHL1/MAPK1/ADAM9/PDGFB/NUP62/P2RX7/SHC1/TRIB3/ILK/DUSP1/AVPI1	115
BP	GO:0043624	cellular protein complex disassembly	79/4749	217/18670	0.0002091	0.005749	0.004677	KIF2C/MICAL1/KIF24/MRPL37/MRPL28/KIF18A/CAPZB/GSN/MRPL51/MRPS36/CKAP2/MRPL22/ASPH/MICAL2/SWAP70/TMOD2/MRPL18/CAPG/ARHGEF2/MRPS5/MRPS18C/MRPS11/PDXP/ADD3/SH3GL1/C12orf65/UPF1/STMN3/MRPS6/SPTBN1/FGF13/ABCE1/N6AMT1/STMN1/CLASP2/TRIOBP/TWF2/CFL1/SPTAN1/MRPL20/MID1/MRPL50/CAPZA1/MRPL36/MRPS2/MRPL35/MRPL27/MRPL15/MAP1S/DNAJC6/MRPS25/TRMT112/MRPL34/TRIM54/WDR1/MRPS14/MRPL13/MICAL3/PTCD3/VILL/NAPB/OGFOD1/GADD45GIP1/MRPL10/MRPL54/GLE1/DAP3/MAP1A/GSPT1/MRPL2/APC/MRPL39/SEMA5A/NCKAP5/KIF19/MRPL43/ADD2/CKAP5/MRPL48	79
BP	GO:0061640	cytoskeleton-dependent cytokinesis	42/4749	100/18670	0.0002123	0.005754	0.004681	KIF20A/ESPL1/AURKB/CENPA/ANLN/KIF4A/CDT1/KIF23/CIT/CEP55/KIF20B/NUSAP1/RACGAP1/RTKN/STAMBP/SNX9/CHMP2B/MYH10/INCENP/BRCA2/PLK1/CKAP2/KIF4B/UNC119/SPTBN1/STMN1/CFL1/ECT2/SNX33/IST1/CHMP1A/CHMP2A/TTC19/APC/MAP9/EFHC1/ARL3/MITD1/ALKBH4/NUP62/CHMP3/KLHDC8B	42
BP	GO:0070498	interleukin-1-mediated signaling pathway	42/4749	100/18670	0.0002123	0.005754	0.004681	EGR1/IL1B/SQSTM1/IL1R1/IL1RN/IL1R2/PSMD8/UBB/PSMD1/PSMD2/UBE2N/PSMF1/IRAK3/RPS27A/TOLLIP/UBA52/NOD2/PSMD9/IRAK1/PSMA5/PSMB7/FBXW11/TAB1/NFKBIA/PSMD5/MAP3K3/PSME2/BTRC/ST18/PSMB5/RIPK2/PSMB4/TRAF6/PSMA3/ZNF675/PSMD10/PLCB1/PSMB1/PSMD7/PSMB3/PSMC5/PSMD11	42
BP	GO:0060606	tube closure	39/4749	91/18670	0.0002127	0.005754	0.004681	TWIST1/SDC4/STIL/MTHFD1L/KIF20B/PLXNB2/PTCH1/ST14/SEMA4C/SKI/ALX1/CTHRC1/DVL3/FZD6/PTK7/KAT2A/LMO4/ARHGAP35/SPINT1/LIAS/SALL4/VASP/IFT122/DVL1/MTHFD1/SCRIB/IFT172/RALA/ARID1A/SHROOM3/SFRP1/ADM/LRP6/PRKACB/TRAF6/MED12/TGFB1/GLMN/RARA	39
BP	GO:0014020	primary neural tube formation	41/4749	97/18670	0.0002131	0.005754	0.004681	TWIST1/SDC4/STIL/MTHFD1L/LUZP1/KIF20B/PLXNB2/PTCH1/ST14/SEMA4C/SKI/ALX1/CTHRC1/DVL3/FZD6/PTK7/KAT2A/LMO4/ARHGAP35/SPINT1/LIAS/SALL4/VASP/IFT122/CFL1/DVL1/MTHFD1/SCRIB/IFT172/RALA/ARID1A/SHROOM3/SFRP1/ADM/LRP6/PRKACB/TRAF6/MED12/TGFB1/GLMN/RARA	41
BP	GO:0002478	antigen processing and presentation of exogenous peptide antigen	66/4749	175/18670	0.0002138	0.005754	0.004681	KIF2C/KIF4A/KIF15/KIF23/FCGR1B/SEC13/NCF4/RACGAP1/KIF18A/IFI30/SEC24D/CAPZB/CYBB/HLA-DQB2/KIF11/HLA-DMA/KLC1/FCGR1A/HLA-H/CENPE/CD207/HLA-G/PSMD8/KIF4B/PSMD1/PSMD2/CD74/CTSF/PSMF1/DCTN5/HLA-DPA1/HLA-E/HLA-DRA/AP1S1/PSMD9/AP2S1/SNAP23/CTSD/PSMA5/LAG3/TAP1/CAPZA1/KIF3C/PSMB7/VAMP3/PSMD5/HLA-DMB/CYBA/HLA-DQA2/PSME2/PSMB5/ACTR1A/CANX/LNPEP/PSMB4/HLA-DPB1/TRAF6/PSMA3/NCF1/PSMD10/PSMB1/PSMD7/PSMB3/HLA-DRB1/PSMC5/PSMD11	66
BP	GO:0002711	positive regulation of T cell mediated immunity	24/4749	48/18670	0.0002173	0.005794	0.004713	IL1B/CD1E/IL18/NLRP3/IL1R1/TNFSF4/CD1A/FOXP3/CD1C/RSAD2/HLA-H/HLA-G/CD1B/CD1D/PTPRC/HLA-E/IL12RB1/IL18R1/TRAF2/TRAF6/FZD5/GATA3/P2RX7/IL23A	24
BP	GO:0071902	positive regulation of protein serine/threonine kinase activity	114/4749	334/18670	0.0002186	0.005794	0.004713	IQGAP3/IL1B/MAPK11/VEGFA/TP73/CDK1/GADD45G/CSF1R/FPR1/NTRK1/PDGFA/DUSP6/CAMK1/CDC6/SYAP1/TNF/ADRA2B/FGD2/TLR4/PTPN1/GADD45A/PEA15/TRAF7/PSRC1/CKS2/CCNB1/SRC/TENM1/MAP3K6/ARHGEF5/DBF4/TIAM1/MAP2K3/DUSP5/DBF4B/ARRB1/HTR2A/MAP3K2/NTRK3/DVL3/UBB/TGFB3/CD74/PAK1/CKS1B/PKD2/UBE2N/RPS3/MAP2K6/ACSL1/PIK3R5/FLT3/RPS27A/PAK3/MAP3K5/PTPRC/STK3/CCNT2/ITGA1/EZH2/NRK/UBA52/PARP16/PPP2CA/NOD2/ATP2B4/MAP3K11/IRAK1/FLT1/TAOK3/TLR6/FZD8/RAPGEF1/ERBB2/TAB1/CCNK/CRK/MAP3K3/MAP2K4/RAPGEF2/TRAF2/GHRL/ETAA1/ADIPOQ/MAP4K1/ERN1/RIPK2/F2R/MAPKAPK2/MNAT1/LAMTOR2/INSR/TRAF6/BIRC7/CCNY/AKAP13/RALB/TNFSF11/FZD5/NTF3/PSMD10/MAP3K9/TGFB1/SHC2/MAPK1/CCND1/ADAM9/PDGFB/P2RX7/SHC1/MLST8/ILK/SIRT1/AVPI1	114
BP	GO:1901292	nucleoside phosphate catabolic process	70/4749	188/18670	0.0002188	0.005794	0.004713	TPI1/DCTPP1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/PDE4A/GPI/CBFA2T3/SIRT6/HK2/NUP98/ENTPD5/GPX1/ABCD1/CNP/STAT3/NUDT16/NUDT1/PGM2L1/PKM/PDE4D/ALDOC/VCP/OGDH/HTR2A/PDE4B/PFKFB4/HPRT1/ENTPD2/NUP153/PNP/DDIT4/GALK1/PFKFB2/NUP88/ENO3/PRKAG2/POM121C/NUP205/RAE1/NUDT17/NUP50/SAMHD1/ENTPD4/NUDT3/ALDOA/AMPD3/NT5E/PDE7B/INSR/NUPR1/NUP93/NEIL1/PFKL/ALDOB/NUP35/OGG1/AAAS/NT5C2/NUP62/P2RX7/SEH1L/NCOR1/ASPDH	70
BP	GO:2001020	regulation of response to DNA damage stimulus	78/4749	214/18670	0.0002189	0.005794	0.004713	TWIST1/SKIL/FOXM1/CASP9/SPRED2/DYRK3/ZNF385A/MCL1/IER3/PML/HMGB1/SIRT6/PMAIP1/RAD51/MSX1/RAD51AP1/NUDT16/PARPBP/RMI2/SNAI1/DTX3L/FBXO5/RPL26/TP53BP1/CLU/CRY1/CD74/POLQ/RFWD3/MAGEF1/UBE2N/RPS3/EYA2/CBX8/BID/EID3/TFIP11/ERCC8/FIGNL1/TIMELESS/TAF9B/MUC1/RECQL5/FEM1B/RNF8/BRCC3/WDR76/FMR1/BCL2L12/CHEK1/CD44/BCL2L1/XRCC1/WRAP53/AUNIP/DDX11/PIAS4/ETAA1/MAD2L2/HELB/ATR/CHEK2/RAD52/FAM168A/AXIN2/OGG1/ATM/PSMD10/CUL4A/WAS/MGMT/HDAC10/ERCC1/FBXO4/RNF168/TERF2/RAD9A/SIRT1	78
BP	GO:0000724	double-strand break repair via homologous recombination	53/4749	134/18670	0.0002217	0.005825	0.004739	RBBP8/MCM4/MCM5/SFPQ/RAD54L/SIRT6/BRCA2/AP5S1/ZSWIM7/FEN1/RAD51/RAD51AP1/PARPBP/MCM2/RMI2/TONSL/TP53BP1/CDC45/GINS2/DMC1/POLQ/RFWD3/MAGEF1/GINS4/UBE2N/MCM7/HELQ/FIGNL1/TIMELESS/RECQL5/MCM3/REC8/CHEK1/RECQL4/SAMHD1/XRCC3/XRCC1/SFR1/WRAP53/AUNIP/MAD2L2/HELB/RAD52/POLN/ATM/NUCKS1/WDR48/WRN/SMC5/FAN1/RNF138/WAS/RAD54B	53
BP	GO:0009896	positive regulation of catabolic process	140/4749	423/18670	0.0002223	0.005825	0.004739	TWIST1/IL1B/RNF144A/FURIN/DTL/AURKA/GPSM1/TRIB1/BNIP3L/PFKFB3/TP53INP2/SGSM3/SNX9/HMGB1/CBFA2T3/TNF/ZFP36/HK2/HSPA1A/ZC3H12D/PLK2/ECSCR/BAX/PLEKHN1/PTPN1/PLK1/ENTPD5/DET1/LDLR/ABCD1/SNF8/SMAD7/SORL1/STX5/HMOX1/DTX3L/ABCD2/NKD1/VCP/HTR2A/PIM2/CLU/TNRC6B/PFKFB4/MAGEF1/HERPUD1/MYLIP/HTT/FYCO1/AMBRA1/UPF1/TRIM22/CALCOCO2/FOXO1/RNF40/ZFP36L2/SGTA/SMURF1/TPCN1/PINK1/OAZ3/PIAS1/EZR/BCAP31/TRIM13/DVL1/ULK1/PFKFB2/MEX3D/LRP1/GBA/TP53INP1/SUMO1/RNF19B/MID2/RHBDD3/PARK7/RBM23/SH3BP4/FMR1/TNFSF12/OAZ2/RAD23A/PRKCE/KIAA1324/ASB11/SNX33/EDEM2/USP5/TFEB/ZC3H12A/BAG3/UVRAG/LACRT/GSK3A/PHKG2/CNOT7/YTHDF3/UBQLN2/BAG2/DAPK1/METTL16/SIRT2/GIGYF2/IL4/CPT1A/ZFAND2A/RIPK2/TNFRSF1B/ZC3HAV1/ATG4B/RNF139/LRSAM1/ZFP36L1/GCLC/NNT/INSR/NUPR1/OSBPL7/PIP4K2A/APC/VPS13D/OAZ1/RALB/PIP4K2B/ATM/PSMD10/ATG7/NDUFA13/DNAJB2/ADAM9/SESN2/P2RX7/KHSRP/BAD/BARD1/TRIB3/RAB12/SIRT1/NPRL2	140
BP	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	29/4749	62/18670	0.0002237	0.005825	0.004739	CHAC1/PML/SERINC3/HSPA1A/BAX/PTPN1/PMAIP1/SYVN1/ATP2A1/HERPUD1/ATF4/TNFRSF10B/MAP3K5/BAK1/TMEM117/DDIT3/PARK7/TXNDC12/CEBPB/BCL2L1/BRSK2/TRAF2/EIF2AK3/ERN1/PPP1R15A/PDX1/RNF186/TRIB3/SIRT1	29
BP	GO:1902686	mitochondrial outer membrane permeabilization involved in programmed cell death	29/4749	62/18670	0.0002237	0.005825	0.004739	PPIF/TP73/BNIP3L/YWHAH/YWHAE/TP63/YWHAZ/E2F1/HSPA1A/BAX/PMAIP1/MOAP1/SFN/BMF/HIP1R/EYA2/NMT1/BID/TFDP2/BAK1/YWHAQ/SLC25A5/STPG1/ZNF205/GSK3A/RHOT2/FZD9/SPG7/BAD	29
BP	GO:1903320	regulation of protein modification by small protein conjugation or removal	83/4749	231/18670	0.0002414	0.006261	0.005094	EGR1/NDFIP2/UBE2C/ISG15/CDC20/FANCI/CDK5/DNAJA1/GORASP1/UBE2S/HSPA5/HSPA1A/DERL1/ARRDC3/PLK1/PIAS3/MTOR/SMAD7/TSPO/DTX3L/RPL5/FBXO5/ARRB1/VCP/UBE2I/UBB/CRY1/HERPUD1/PER2/UBE2N/RPS3/N4BP1/UBXN1/RNF40/TOLLIP/RPL23/PINK1/NXN/PIAS1/ARRDC4/TRIM44/NOD2/FKBP1A/TANK/FEM1B/LIMK1/GNL3/CHP1/PARK7/UBE3A/RASD2/TOPORS/USP44/PRKCE/HMG20A/ZC3H12A/DCUN1D4/SIAH2/BIRC3/GSK3A/BAG2/PIAS4/CDC14B/RIPK2/GCLC/MAD2L2/TRAF6/BIRC7/MTA1/RAB1A/RPL11/HMG20B/WDR48/PSMD10/PHF23/GLMN/DNAJB2/BMI1/PEF1/FBXO4/FYN/TRIB3/MAGEA2B	83
BP	GO:0009165	nucleotide biosynthetic process	129/4749	386/18670	0.0002445	0.006316	0.005138	TPI1/PDPR/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/PTGIS/ENO1/PGAM1/PFKP/TYMS/GPI/CBFA2T3/SIRT6/DHODH/HK2/AGPAT3/SLC25A1/RRM2B/NUP98/ENTPD5/AGPAT2/TECR/CMPK2/DNAJC30/STAT3/ERH/ADCY4/DTYMK/PFAS/SCD/PGM2L1/PKM/AK5/ALDOC/VCP/OGDH/HTR2A/RRM1/PDHB/PPT1/PFKFB4/HPRT1/ADCY6/NUP153/ACSL1/PDHX/AK3/GUCA1C/PNP/NME4/PINK1/HSD17B8/NAMPT/UPRT/DDIT4/NADK/SLC35B2/DCTD/VPS9D1/PRPSAP2/GALK1/MTHFD1/PARP16/PFKFB2/DLAT/NUP88/ENO3/AMPD2/PRKAG2/NME3/ELOVL7/POM121C/AK4/NUP205/RAE1/ELOVL1/IDO1/ADCY3/NUP50/APRT/IMPDH1/ACSL4/RRM2/ALDOA/GUK1/AMPD3/IL4/PANK4/ACACB/TAMM41/RNLS/LCLAT1/AK1/CMPK1/CTPS2/ACSS1/UCK2/FASN/INSR/NUPR1/ADCY9/SPHK2/PRPS1/NUP93/PFKL/PAPSS2/ALDOB/NUP35/NME9/PANK1/AAAS/TAZ/AK2/TGFB1/MPC1/GPAT2/NMNAT1/MAPK1/GSTZ1/NMNAT3/NUP62/P2RX7/SEH1L/NCOR1/NME2/ASPDH	129
BP	GO:0032886	regulation of microtubule-based process	79/4749	218/18670	0.0002473	0.006349	0.005165	CCNF/GPSM2/TPX2/SKA1/STIL/MAP6/AURKA/FES/NEK2/RAC1/SKA3/TACC3/SPAG5/BBS2/KIF18A/PLK4/SMC3/CHMP2B/ATF5/HSPA1A/PLK2/KIF11/PLK1/CENPJ/CKAP2/RANGRF/FSD1/PSRC1/MAPRE2/NUMA1/ARHGEF2/CLIP3/CNIH2/PAK1/KAT2A/CDK2AP2/POC1A/RPS3/NUBP1/STMN3/MDM1/TERF1/FGF13/CEP70/CYLD/STMN1/CLASP2/CHORDC1/MKKS/MID1/TUBB4A/MAP1S/ERBB2/CHEK1/MARK4/RAE1/TRIM54/C10orf90/ALMS1/XRCC3/GSK3A/PHLDB1/LAMP1/CHMP1A/NSFL1C/TMEM67/CHMP2A/MAP1A/APC/SMC1A/MAP9/ARL2/SENP6/MCPH1/SLAIN2/CEP97/CDH5/NUP62/CHMP3	79
BP	GO:0051099	positive regulation of binding	67/4749	179/18670	0.0002478	0.006349	0.005165	TWIST1/CDCA5/CDT1/PPARG/ITGA2/GPSM1/KLF4/IRF4/PLAUR/TIRAP/CDK5/ANXA2P2/LGALS3/MMP9/GMNN/SYAP1/HMGB1/PLK2/SKI/DERL1/SPPL3/ANXA2/DTX3L/TIAM1/CTHRC1/MBD2/ARRB1/HIP1R/TCF7L2/STK3/STMN1/PLXND1/FLOT1/VTN/S100A10/PPP2CA/ACD/TRAF4/FKBP1A/LRP1/PLCL2/PARK7/FMR1/ERCC2/EPB41L5/SPON1/STPG1/RAPGEF2/DDX11/TRAF2/SIRT2/RIPK2/EDF1/EPB41/TRAF6/ARF6/RPL11/RALB/EIF3E/TGFB1/POU4F1/RARA/GATA3/CRBN/PDX1/ADD2/TRIB3	67
BP	GO:0044843	cell cycle G1/S phase transition	103/4749	298/18670	0.0002554	0.006463	0.005258	IQGAP3/BCAT1/KIF14/GTSE1/E2F7/E2F8/FAM83D/CDK1/CDT1/RBBP8/CDKN1A/AURKA/CDKN3/KANK2/CDKN2B/KLF4/PTPN6/CCNA2/MCM4/ZNF385A/MCM5/GPNMB/CDC25A/CDC6/GMNN/PML/TYMS/MCM10/EIF4EBP1/E2F1/PLK2/BAX/BTN2A2/CDC25C/CDKN2C/GADD45A/NASP/CCNB1/MCM2/FBXO5/DBF4/SFN/RPL26/RPS6/CDC45/PIM2/CDK2/CAMK2A/ORC1/RFWD3/CDK2AP2/PKD2/CCNE2/CCL2/MCM7/DHFR/FBXO31/BID/CARM1/CDK7/PIAS1/AIF1/BRD4/CNOT3/EZH2/CDK10/TFDP2/MUC1/CDKN2A/ATP2B4/TAF10/MDM4/POLE/MCM3/GPR132/CUL5/RBL2/RCC1/PSME2/CNOT7/RRM2/NPAT/RHOU/TMEM14B/GIGYF2/CRLF3/GML/MNAT1/CHEK2/MAX/GSPT1/BACH1/ADAMTS1/ATM/PPP6C/ANKRD17/PLCB1/CUL4A/ORC2/ZNF655/CCND1/PHF8/POLE2	103
BP	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	78/4749	215/18670	0.000259	0.006463	0.005258	VEGFA/GRAMD4/PPARG/NLRP3/BIRC5/CASP9/ADORA2A/MICAL1/KLF4/CTSH/PLAUR/RFFL/CLEC7A/HIP1/MMP9/YWHAE/TP63/LGALS9/PML/HMGB1/TNF/GSN/NOL3/BAX/TNFAIP8/PMAIP1/GPX1/CARD9/DAP/SRC/IFI6/PRDX3/P2RX1/SFN/CFLAR/ARRB1/VCP/BCL2L13/HERPUD1/PRDX5/RPS3/HIP1R/PDCD5/CCK/FAS/BID/TNFRSF10B/MAP3K5/BCAP31/KHDC1/BAK1/CTSD/CASP8AP2/PARK7/TFAP2B/BCL2L12/ACVR1C/CD44/ACER2/SIAH2/BIRC3/DAPK1/TRAF2/DNAJB6/EIF2AK3/S100A8/ST18/F3/F2R/POR/TNFSF10/BIRC7/CARD8/NDUFA13/MGMT/BAD/PAK2/SIRT1	78
BP	GO:0002507	tolerance induction	15/4749	25/18670	0.0002612	0.006463	0.005258	PDCD1/LGALS9/HMGB1/IL2RA/FOXP3/CCR4/HLA-G/HAVCR2/IRAK3/HLA-E/LILRB2/PHLPP1/IDO1/CD3E/TGFB1	15
BP	GO:2000104	negative regulation of DNA-dependent DNA replication	15/4749	25/18670	0.0002612	0.006463	0.005258	BCL6/GMNN/SMC3/MSH6/BRCA2/FBXO5/ZRANB3/TERF1/TIMELESS/ZNF830/CHEK2/SMC1A/ATG7/TIPIN/TERF2	15
BP	GO:0050714	positive regulation of protein secretion	94/4749	268/18670	0.0002615	0.006463	0.005258	TWIST1/IL1B/MAPK11/NLRP3/ADORA2A/CSF1R/IL10/ABCG1/RAC1/TLR8/IL17A/GAPDH/HK1/TNFSF4/LGALS9/GPI/MYH10/HMGB1/TNF/TNFRSF4/BLK/TLR4/LILRA2/MMP12/IL4R/FFAR2/FRMD4A/FCN1/SRC/ABAT/ARRB1/CCL3/ATP13A2/PTGER4/HAVCR2/C2CD2L/SRI/CD33/TGFB3/CASR/TCF7L2/SPTBN1/EZR/TRPM4/NADK/HLA-E/AIF1/OXCT1/TLR2/KCNN4/PFKFB2/CD58/NOD2/PSMD9/LRP1/IL26/OSM/CADM1/SIRT3/C1QTNF3/IL17RC/PRKCE/IRF3/GLUD1/PAEP/LILRA5/IL13/CD2AP/IFNGR1/GHRL/CD34/RIPK2/MYOM1/F2R/SERP1/DOC2B/CLEC5A/ARF6/CARD8/PARD6A/FZD5/PPARD/FFAR1/TGFB1/GLMN/ADAM9/TRIM16/GATA3/PDX1/P2RX7/GIPR/SYBU/VEGFC/BAD	94
BP	GO:0048002	antigen processing and presentation of peptide antigen	70/4749	189/18670	0.0002621	0.006463	0.005258	KIF2C/KIF4A/KIF15/KIF23/FCGR1B/SEC13/NCF4/RACGAP1/KIF18A/IFI30/SEC24D/CAPZB/CYBB/HLA-DQB2/KIF11/HLA-DMA/KLC1/FCGR1A/HLA-H/CENPE/CD207/HLA-G/PSMD8/KIF4B/PSMD1/PSMD2/CD74/CTSF/PSMF1/DCTN5/HLA-DPA1/BCAP31/TAPBPL/HLA-E/HLA-DRA/AP1S1/PSMD9/AP2S1/SNAP23/CTSD/PSMA5/LAG3/TAP1/CAPZA1/KIF3C/MR1/PSMB7/VAMP3/PSMD5/HLA-DMB/CYBA/HLA-DQA2/ERAP1/PSME2/PSMB5/ACTR1A/CANX/LNPEP/PSMB4/HLA-DPB1/TRAF6/PSMA3/NCF1/PSMD10/PSMB1/PSMD7/PSMB3/HLA-DRB1/PSMC5/PSMD11	70
BP	GO:0002763	positive regulation of myeloid leukocyte differentiation	26/4749	54/18670	0.0002623	0.006463	0.005258	LIF/TRIB1/FES/IL17A/CCR1/TNF/CSF1/PPARGC1B/GNAS/CD74/PRKCA/JUN/CA2/KLF10/IL20/TYROBP/ZFP36L1/TESC/TRAF6/TNFSF11/FOS/SLC9B2/TGFB1/TMEM64/POU4F1/IL23A	26
BP	GO:0007091	metaphase/anaphase transition of mitotic cell cycle	26/4749	54/18670	0.0002623	0.006463	0.005258	ESPL1/CENPF/AURKB/BUB1B/TTK/CDT1/TRIP13/CDC20/DLGAP5/BUB1/TACC3/CDC6/PLK1/CCNB1/CENPE/FBXO5/NDC80/ANAPC11/USP44/ANAPC1/XRCC3/MAD2L2/KLHL22/APC/ATM/DUSP1	26
BP	GO:0032655	regulation of interleukin-12 production	26/4749	54/18670	0.0002623	0.006463	0.005258	MAPK11/IL10/ACP5/TLR8/TIRAP/TNFSF4/CLEC7A/LGALS9/HMGB1/IRF5/TLR4/HLA-G/TIGIT/IRAK3/CD47/TLR2/MAST2/PIBF1/IDO1/LILRA5/RIPK2/C1QBP/TRAF6/PLCB1/JAK3/IL23A	26
BP	GO:0097345	mitochondrial outer membrane permeabilization	26/4749	54/18670	0.0002623	0.006463	0.005258	TP73/BNIP3L/YWHAH/YWHAE/TP63/YWHAZ/E2F1/HSPA1A/BAX/PMAIP1/MOAP1/SFN/BMF/HIP1R/EYA2/NMT1/BID/TFDP2/BAK1/YWHAQ/SLC25A5/ZNF205/GSK3A/RHOT2/FZD9/BAD	26
BP	GO:0033045	regulation of sister chromatid segregation	35/4749	80/18670	0.0002726	0.006692	0.005444	ESPL1/CENPF/AURKB/CDCA5/BUB1B/TTK/CDT1/TRIP13/CDC20/PTTG1/DLGAP5/BUB1/TACC3/SFPQ/CDC6/PLK1/FEN1/CCNB1/RMI2/CENPE/FBXO5/NUMA1/NDC80/ANAPC11/USP44/ANAPC1/XRCC3/DDX11/MAD2L2/KLHL22/APC/AXIN2/ATM/SMC5/DUSP1	35
BP	GO:0000725	recombinational repair	53/4749	135/18670	0.0002758	0.006743	0.005486	RBBP8/MCM4/MCM5/SFPQ/RAD54L/SIRT6/BRCA2/AP5S1/ZSWIM7/FEN1/RAD51/RAD51AP1/PARPBP/MCM2/RMI2/TONSL/TP53BP1/CDC45/GINS2/DMC1/POLQ/RFWD3/MAGEF1/GINS4/UBE2N/MCM7/HELQ/FIGNL1/TIMELESS/RECQL5/MCM3/REC8/CHEK1/RECQL4/SAMHD1/XRCC3/XRCC1/SFR1/WRAP53/AUNIP/MAD2L2/HELB/RAD52/POLN/ATM/NUCKS1/WDR48/WRN/SMC5/FAN1/RNF138/WAS/RAD54B	53
BP	GO:0010965	regulation of mitotic sister chromatid separation	27/4749	57/18670	0.0002819	0.006788	0.005523	ESPL1/CENPF/AURKB/BUB1B/TTK/CDT1/TRIP13/CDC20/PTTG1/DLGAP5/BUB1/TACC3/CDC6/PLK1/CCNB1/CENPE/FBXO5/NDC80/ANAPC11/USP44/ANAPC1/XRCC3/MAD2L2/KLHL22/APC/ATM/DUSP1	27
BP	GO:0051310	metaphase plate congression	27/4749	57/18670	0.0002819	0.006788	0.005523	CENPF/KIF2C/CDCA8/KIF14/KIFC1/CDCA5/FAM83D/GEM/CDT1/SPAG5/KIF18A/CHMP2B/NUF2/PSRC1/CCNB1/CENPE/NUMA1/NDC80/BOD1/TTL/PIBF1/CHMP1A/CHMP2A/CHAMP1/TRAPPC12/NUP62/SEH1L	27
BP	GO:0072431	signal transduction involved in mitotic G1 DNA damage checkpoint	27/4749	57/18670	0.0002819	0.006788	0.005523	GTSE1/E2F7/E2F8/CDK1/CDKN1A/AURKA/ZNF385A/PML/E2F1/PLK2/BAX/CDC25C/GADD45A/CCNB1/SFN/RPL26/CDK2/CARM1/CNOT3/TFDP2/MUC1/MDM4/RBL2/CNOT7/GML/CHEK2/ATM	27
BP	GO:1902400	intracellular signal transduction involved in G1 DNA damage checkpoint	27/4749	57/18670	0.0002819	0.006788	0.005523	GTSE1/E2F7/E2F8/CDK1/CDKN1A/AURKA/ZNF385A/PML/E2F1/PLK2/BAX/CDC25C/GADD45A/CCNB1/SFN/RPL26/CDK2/CARM1/CNOT3/TFDP2/MUC1/MDM4/RBL2/CNOT7/GML/CHEK2/ATM	27
BP	GO:0051090	regulation of DNA-binding transcription factor activity	142/4749	432/18670	0.0002831	0.006793	0.005527	TWIST1/IL1B/MAPK11/VEGFA/IL18/PPARG/NLRP3/ICAM1/FOSL1/IL10/TRIB1/NTRK1/SRF/KLF4/HCK/PTGIS/TIRAP/TNFSF4/LGALS9/PTCH1/NFKB2/TNF/TNFRSF4/LRP8/NFKBIE/HSPA1A/CD200/TLR4/TRIM25/FOXP3/TRIM26/WNT10B/SMARCB1/CRTC2/STAT3/SMAD7/PIM1/RIPK3/DAP/HMOX1/PRDX3/PPARGC1B/ARHGEF5/TONSL/TRAIP/ARHGEF2/TP53BP1/CFLAR/TRIM62/ARRB1/BTK/CLU/GLIS2/CAMK2A/HAVCR2/SRI/UBB/SFRP4/SETD6/FZD6/ARID5B/PKD2/CREBZF/CRTC1/UBE2N/RPS3/CTH/BHLHE40/IRAK3/TRIM22/RPS27A/TCF7L2/CARM1/SMARCA4/PINK1/SIGIRR/LRRC14/CYLD/STK3/NFAM1/TBX6/PRKCI/EZH2/UBA52/TLR2/TRIM13/FLOT1/CDKN2A/NOD2/IRAK1/DDIT3/SUMO1/DHX33/IL18R1/TLR6/CHP1/MID2/PARK7/JUN/TAB1/ANXA4/NFKBIA/TRAF1/NFKBIL1/NLRC3/ZC3H12A/TRIM52/C3orf33/RLIM/BTRC/TRAF2/CARD11/PIAS4/S100A8/PRNP/RIPK2/ESR1/KDM5A/FER/PPRC1/MAD2L2/LRP6/PRKCB/MBTPS2/NUPR1/TRAF6/CARD8/TNFSF11/COMMD6/FOS/ZNF675/PSMD10/ID1/TGFB1/MXI1/POU4F1/COMMD7/MAPK1/CX3CR1/TRIM15/SIRT1/TRIM5	142
BP	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	68/4749	183/18670	0.0002855	0.006824	0.005551	NDFIP2/IL1B/IL1RN/TIRAP/TIFA/CANT1/LGALS9/UBD/TNF/PLK2/TLR4/S100A13/TRIM25/IFIT5/CARD9/HMOX1/TGM2/CFLAR/TRIM62/UBE2I/PIM2/BST2/CD74/UBE2N/CTH/LGALS1/TRIM22/TNFRSF19/TNFRSF10B/PINK1/SLC35B2/BRD4/TRIM13/SECTM1/LITAF/NOD2/FKBP1A/IRAK1/TLR6/MID2/PPP5C/PRKCE/ECT2/MAP3K3/IRF3/BIRC3/TMED4/TRAF2/CARD11/ADIPOQ/RIPK2/F2R/TNFSF10/IL36A/PRKCB/TRAF6/AKAP13/GOLT1B/TSPAN6/TNFSF11/EDAR/SHISA5/ANKRD17/NUP62/CX3CR1/FYN/IL37/TRIM5	68
BP	GO:0033260	nuclear DNA replication	28/4749	60/18670	0.0002993	0.007128	0.005799	CDT1/BCL6/MCM4/MCM5/GMNN/BRCA2/FEN1/RAD51/MCM2/DBF4/DBF4B/CDC45/GINS1/UPF1/RFC2/MCM7/TERF1/POLD4/AICDA/POLE/MCM3/ZNF830/DNA2/CHEK2/WIZ/TIPIN/POLE2/TERF2	28
BP	GO:0042089	cytokine biosynthetic process	49/4749	123/18670	0.0003078	0.007302	0.005941	EGR1/EBI3/IL1B/IRF7/CD86/IL18/CD276/IL21/IL10/KLF4/CD80/IRF4/BCL3/TLR8/TIRAP/CLEC7A/TNF/ZFP36/TNFRSF8/CYBB/TLR4/FOXP3/CARD9/STAT3/CCR2/HMOX1/MAP2K3/CD74/PTPRC/SIGIRR/MAST2/LAG3/TLR6/CEBPB/IRF3/CD3E/CARD11/GHRL/IL4/MAPKAPK2/TYROBP/TRAF6/PCSK5/ASB1/GLMN/ZFPM1/GATA3/PTAFR/CX3CR1	49
BP	GO:0032970	regulation of actin filament-based process	129/4749	388/18670	0.0003113	0.007359	0.005987	CDC42EP4/SDC4/FSCN1/PLEKHG2/ICAM1/CIT/CSF1R/FES/PDGFA/HCK/RAC1/CYFIP1/DSC2/CDK5/NF2/FHOD1/SNX9/CAPZB/GSN/CTTN/MTOR/MYADM/RANGRF/BAG4/MYLK2/CDC42EP1/SWAP70/RNF207/TMOD2/TENM1/ARHGEF5/RHOG/CAPG/PAM/PDE4D/CORO1B/ATP2A1/PTGER4/BST2/NTRK3/PDXP/KCNE3/PDE4B/SRI/TGFB3/WHAMMP3/PAK1/KCNJ2/ADD3/PFN2/HIP1R/ARHGAP35/S1PR1/ARPC1B/PAK3/PREX1/PICK1/TMSB4Y/SPTBN1/FGF13/CORO1A/TRPM4/STMN1/CLASP2/CD47/VASP/TRIOBP/TWF2/LIMCH1/CFL1/CDK10/COTL1/SPTAN1/S100A10/ARPC5/MKKS/MYBPC3/LRP1/ARAP1/LIMK1/SUMO1/CAPZA1/SH3PXD2B/CRK/TNNC1/PRKCE/ECT2/ACTR3B/KANK3/WDR1/RHOF/ALMS1/RHOV/TMSB15A/RHOU/VILL/SFRP1/CD2AP/CAMK2D/MYH9/FER/CNN2/ABRACL/BMP10/ARF6/TPM1/ARHGAP18/ARHGDIA/ARHGAP17/AKAP13/SORBS3/NTF3/WASF2/WHAMM/AP1AR/ID1/TGFB1/BCAS3/C15orf62/SEMA5A/CDC42/WAS/FMN1/ADD2/CCL27/MLST8/ILK/RAC3/GJA5	129
BP	GO:0042255	ribosome assembly	29/4749	63/18670	0.0003146	0.007409	0.006027	RPL3/RPS27/RPL38/RPS10/TRAF7/MRPL22/PPAN/RPL23A/RPS5/RPL5/RPS15/MRPS11/RPL6/NSUN4/RPS19/BRIX1/FASTKD2/SBDS/MRPL20/MRPS2/BOP1/RPL12/RPSA/ABT1/RPS28/MRTO4/MDN1/C1QBP/RPL11	29
BP	GO:0009260	ribonucleotide biosynthetic process	101/4749	293/18670	0.0003251	0.007627	0.006205	TPI1/PDPR/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/GPI/CBFA2T3/SIRT6/DHODH/HK2/SLC25A1/NUP98/ENTPD5/TECR/DNAJC30/STAT3/ADCY4/PFAS/SCD/PGM2L1/PKM/AK5/ALDOC/VCP/OGDH/HTR2A/PDHB/PPT1/PFKFB4/HPRT1/ADCY6/NUP153/ACSL1/PDHX/AK3/NME4/PINK1/HSD17B8/UPRT/DDIT4/SLC35B2/VPS9D1/GALK1/PFKFB2/DLAT/NUP88/ENO3/AMPD2/PRKAG2/NME3/ELOVL7/POM121C/AK4/NUP205/RAE1/ELOVL1/ADCY3/NUP50/APRT/IMPDH1/ACSL4/ALDOA/GUK1/AMPD3/IL4/PANK4/ACACB/AK1/CMPK1/CTPS2/ACSS1/UCK2/FASN/INSR/NUPR1/ADCY9/SPHK2/NUP93/PFKL/PAPSS2/ALDOB/NUP35/NME9/PANK1/AAAS/TAZ/AK2/TGFB1/MPC1/GSTZ1/NUP62/P2RX7/SEH1L/NCOR1/NME2	101
BP	GO:1902108	regulation of mitochondrial membrane permeability involved in apoptotic process	30/4749	66/18670	0.0003277	0.007627	0.006205	TP73/BNIP3L/YWHAH/YWHAE/TP63/YWHAZ/E2F1/HSPA1A/NOL3/BAX/PMAIP1/NAIF1/MOAP1/SFN/BMF/CAMK2A/HIP1R/EYA2/NMT1/BID/TFDP2/BAK1/YWHAQ/SLC25A5/STPG1/ZNF205/GSK3A/RHOT2/FZD9/BAD	30
BP	GO:0031331	positive regulation of cellular catabolic process	121/4749	361/18670	0.0003281	0.007627	0.006205	TWIST1/IL1B/RNF144A/FURIN/AURKA/GPSM1/TRIB1/BNIP3L/PFKFB3/TP53INP2/SNX9/HMGB1/CBFA2T3/TNF/ZFP36/HK2/HSPA1A/ZC3H12D/PLK2/ECSCR/BAX/PLEKHN1/PTPN1/PLK1/ENTPD5/DET1/LDLR/ABCD1/SMAD7/HMOX1/DTX3L/ABCD2/VCP/HTR2A/PIM2/CLU/TNRC6B/PFKFB4/MAGEF1/HERPUD1/HTT/FYCO1/AMBRA1/UPF1/TRIM22/CALCOCO2/FOXO1/RNF40/ZFP36L2/SGTA/SMURF1/TPCN1/PINK1/PIAS1/EZR/BCAP31/TRIM13/DVL1/ULK1/PFKFB2/MEX3D/LRP1/GBA/TP53INP1/SUMO1/RNF19B/MID2/PARK7/RBM23/SH3BP4/FMR1/RAD23A/KIAA1324/SNX33/EDEM2/USP5/TFEB/ZC3H12A/BAG3/UVRAG/LACRT/GSK3A/PHKG2/CNOT7/YTHDF3/UBQLN2/BAG2/DAPK1/METTL16/SIRT2/GIGYF2/IL4/CPT1A/ZFAND2A/RIPK2/TNFRSF1B/ZC3HAV1/RNF139/LRSAM1/ZFP36L1/GCLC/NNT/INSR/NUPR1/OSBPL7/PIP4K2A/VPS13D/RALB/PIP4K2B/ATM/PSMD10/DNAJB2/ADAM9/SESN2/P2RX7/KHSRP/BAD/TRIB3/RAB12/SIRT1/NPRL2	121
BP	GO:1903706	regulation of hemopoiesis	154/4749	475/18670	0.0003286	0.007627	0.006205	EGR3/LIF/IRF7/NOTCH1/CD86/IL18/TP73/HMGB3/CSF2/NR4A3/NLRP3/DUSP10/TRIB1/FES/CD83/RASSF2/CD80/PTPN6/IRF4/ISG15/BCL6/IL17A/TNFRSF18/SPI1/CSF3R/CBFB/TNFSF4/CCR1/LGALS3/CEACAM1/PRELID1/LGALS9/PRDM1/HMGB1/TNF/CSF1/ZFP36/HSPA1A/IL2RA/TLR4/BTN2A2/PIAS3/MTOR/FOXP3/ESRRA/CTLA4/STAT3/ZBTB46/IL4R/SMAD7/TOX/PIM1/CCR2/PPARGC1B/TFE3/HLA-G/HSPA9/PSMD8/LILRB4/BTK/GNAS/CCL3/TNRC6B/AXL/PSMD1/PSMD2/CD74/KAT2A/PSMF1/HLX/PPP2R3C/PNP/ZFP36L2/JAG1/PGLYRP3/PTPRC/CYLD/PRKCA/NFAM1/AP3D1/SART1/LILRB2/PSMD9/IL12RB1/PSMA5/OSM/LAG3/CD46/JUN/TOB2/PSMB7/ERBB2/NFKBIA/CA2/PSMD5/CEBPB/IL7R/DTX1/TNFSF9/ZC3H12A/YAP1/TMEM176B/NRARP/KLF10/IL7/PSME2/IL20/BGLAP/SFRP1/CARD11/GABPA/ADIPOQ/P4HTM/IL4/PSMB5/RIPK2/TYROBP/ITGA2B/PURB/ZFP36L1/TESC/PRKCB/PSMB4/TRAF6/PSMA3/STAT1/VNN1/ATP11C/TNFSF11/FOS/DLL1/SLC9B2/ZNF675/PSMD10/TGFB1/TMEM64/CUL4A/PSMB1/PSMD7/POU4F1/JAK3/PSMB3/RARA/MIR17HG/ZAP70/ZFPM1/PSMC5/LDB1/GATA3/TCTA/BAD/NME2/PSMD11/IL23A	154
BP	GO:0002643	regulation of tolerance induction	11/4749	16/18670	0.0003342	0.007674	0.006243	PDCD1/HMGB1/IL2RA/FOXP3/HLA-G/HAVCR2/IRAK3/LILRB2/PHLPP1/IDO1/CD3E	11
BP	GO:0002830	positive regulation of type 2 immune response	11/4749	16/18670	0.0003342	0.007674	0.006243	CD86/IL18/NLRP3/TNFSF4/IL4R/RSAD2/CD74/NOD2/IDO1/RARA/GATA3	11
BP	GO:0051444	negative regulation of ubiquitin-protein transferase activity	11/4749	16/18670	0.0003342	0.007674	0.006243	SMAD7/DTX3L/RPL5/FBXO5/RPL23/LIMK1/PARK7/USP44/BAG2/MAD2L2/RPL11	11
BP	GO:0046390	ribose phosphate biosynthetic process	103/4749	300/18670	0.0003366	0.007692	0.006258	TPI1/PDPR/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/GPI/CBFA2T3/SIRT6/DHODH/HK2/SLC25A1/NUP98/ENTPD5/TECR/DNAJC30/STAT3/ADCY4/PFAS/SCD/PGM2L1/PKM/AK5/ALDOC/VCP/OGDH/HTR2A/PDHB/PPT1/PFKFB4/HPRT1/ADCY6/NUP153/ACSL1/PDHX/AK3/NME4/PINK1/HSD17B8/UPRT/DDIT4/SLC35B2/VPS9D1/PRPSAP2/GALK1/PFKFB2/DLAT/NUP88/ENO3/AMPD2/PRKAG2/NME3/ELOVL7/POM121C/AK4/NUP205/RAE1/ELOVL1/ADCY3/NUP50/APRT/IMPDH1/ACSL4/ALDOA/GUK1/AMPD3/IL4/PANK4/ACACB/AK1/CMPK1/CTPS2/ACSS1/UCK2/FASN/INSR/NUPR1/ADCY9/SPHK2/PRPS1/NUP93/PFKL/PAPSS2/ALDOB/NUP35/NME9/PANK1/AAAS/TAZ/AK2/TGFB1/MPC1/GSTZ1/NUP62/P2RX7/SEH1L/NCOR1/NME2	103
BP	GO:0043901	negative regulation of multi-organism process	64/4749	171/18670	0.0003374	0.007692	0.006258	TRIB1/IFIT1/ISG15/ANXA2P2/APOBEC3H/PML/MX1/TNF/ZFP36/GSN/IL2RA/LILRA2/TRIM25/ANXA2/TRIM26/IFIT5/RSAD2/ASTL/FCN1/IFITM2/SEC14L1/TRIM62/CCL3/BST2/MORC2/HAVCR2/OASL/NPLOC4/ISG20/OVGP1/SIGIRR/TRIM13/BANF1/IFITM3/AICDA/IFITM1/MID2/JUN/ACVR1C/TIMP1/CCNK/DEFB114/ZNF639/NFKBIL1/ZC3H12A/PAEP/LACRT/OAS1/IFI16/SIRT2/ILF3/ZC3HAV1/C1QBP/KRT6A/TRIM35/TSPAN6/STAT1/CARD8/HTRA1/SIGLEC11/SETDB1/CHMP3/TRIM15/TRIM5	64
BP	GO:2001236	regulation of extrinsic apoptotic signaling pathway	59/4749	155/18670	0.0003395	0.007713	0.006275	G0S2/SKIL/IL1B/CSF2/ICAM1/FAIM2/RFFL/MCL1/LGALS3/ATF3/PPP2R1A/PML/TNFRSF12A/TNF/HSPA1A/CTTN/NOL3/SERPINE1/PEA15/PMAIP1/GPX1/LMNA/SRC/IFI6/HMOX1/ARHGEF2/TMC8/CFLAR/HTT/EYA2/PHIP/FAS/TCF7L2/BID/TNFRSF10B/PTPRC/CYLD/STRADB/STK3/ITGA6/FEM1B/WWOX/PARK7/TNFSF12/TRAF1/DEPTOR/BCL2L1/YAP1/IL7/SIAH2/CTNNA1/SFRP1/TRAF2/TNFSF10/GCLC/ITM2C/TIMP3/FYN/PAK2	59
BP	GO:0002708	positive regulation of lymphocyte mediated immunity	43/4749	105/18670	0.0003486	0.007891	0.006419	IL1B/CD1E/IL18/IL21/NLRP3/IL1R1/TNFSF4/TFRC/ULBP2/TNF/CD1A/FOXP3/RAET1E/CD1C/RSAD2/HLA-H/HLA-G/TP53BP1/SH2D1A/BTK/CD1B/CD1D/PTPRC/HLA-E/MICA/IL12RB1/LAG3/CADM1/LTA/IL18R1/TRAF2/LAMP1/TNFSF13/IL4/ULBP1/MAD2L2/TRAF6/FZD5/TGFB1/KLRK1/GATA3/P2RX7/IL23A	43
BP	GO:0001773	myeloid dendritic cell activation	16/4749	28/18670	0.0003554	0.007961	0.006476	RELB/CSF2/IL10/BATF/TSPAN32/IRF4/SPI1/UBD/HMGB1/HAVCR2/RBPJ/CLEC4D/IL4/DHRS2/TRAF6/TGFB1	16
BP	GO:0061615	glycolytic process through fructose-6-phosphate	16/4749	28/18670	0.0003554	0.007961	0.006476	TPI1/GAPDH/HK1/ENO1/PGAM1/PFKP/GPI/HK2/PGM2L1/PKM/ALDOC/GALK1/ENO3/ALDOA/PFKL/ALDOB	16
BP	GO:0061620	glycolytic process through glucose-6-phosphate	16/4749	28/18670	0.0003554	0.007961	0.006476	TPI1/GAPDH/HK1/ENO1/PGAM1/PFKP/GPI/HK2/PGM2L1/PKM/ALDOC/GALK1/ENO3/ALDOA/PFKL/ALDOB	16
BP	GO:0006732	coenzyme metabolic process	133/4749	403/18670	0.0003597	0.007991	0.006501	MTHFD2/MTHFD1L/TPI1/PDPR/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/PTGIS/ENO1/PGAM1/PFKP/ACSM3/TYMS/ACOT11/GAMT/GPI/CBFA2T3/SIRT6/HK2/SLC25A1/NUP98/FDXR/PPTC7/ENTPD5/TPK1/TECR/ABCD1/SLC2A3/THEM5/TP53I3/STAT3/PMVK/VNN2/SCD/PGM2L1/PKM/GGH/FAR2/ALDOC/VCP/OGDH/HTR2A/PDXP/PDHB/ACBD6/PPT1/MTHFS/PFKFB4/HMGCL/NUP153/ACSL1/PDHX/MDH2/DHFR/GSTO1/HSD17B8/NAMPT/ACOT8/LIAS/DDIT4/MRI1/NADK/GALK1/DLST/MTHFD1/PARP16/PFKFB2/DLAT/NUP88/ENO3/SHPK/PRKAG2/ELOVL7/MTRR/POM121C/NUP205/RAE1/ELOVL1/NUDT17/IDO1/MOCS1/NUP50/ACSL4/NDUFA9/METTL16/ALDOA/GNMT/ENOPH1/PANK4/OXSM/DGAT2/COQ10A/ACACB/SLC23A2/NT5E/FMO2/GCLC/RNLS/AASDHPPT/NNT/ACSS1/RPE/FASN/PCCB/INSR/NUPR1/NUP93/VNN1/PFKL/NFS1/ALDOB/NUP35/SPR/PGD/PANK1/AAAS/MPC1/NMNAT1/ACOT6/GSTZ1/NMNAT3/NUP62/SLC25A16/PDZD11/AKR1A1/P2RX7/SEH1L/NCOR1/BHMT2/ASPDH	133
BP	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	40/4749	96/18670	0.0003618	0.007991	0.006501	FCGR1B/SEC13/NCF4/IFI30/SEC24D/CYBB/FCGR1A/HLA-H/CD207/HLA-G/PSMD8/PSMD1/PSMD2/PSMF1/BCAP31/TAPBPL/HLA-E/PSMD9/SNAP23/PSMA5/TAP1/MR1/PSMB7/VAMP3/PSMD5/CYBA/ERAP1/PSME2/PSMB5/CANX/LNPEP/PSMB4/PSMA3/NCF1/PSMD10/PSMB1/PSMD7/PSMB3/PSMC5/PSMD11	40
BP	GO:1990823	response to leukemia inhibitory factor	40/4749	96/18670	0.0003618	0.007991	0.006501	ICAM1/KLF4/TFRC/MYBL2/PFKP/TLE4/PML/RFX2/HK2/TRIM25/SBNO2/SMAD7/SOCS3/GLDC/ARID5B/CTH/KDM5B/B3GNT2/EED/MRAS/PARP16/NCL/EFHC2/ILDR1/MRPL15/SLC25A5/INA/DTX1/PADI2/SYNGR1/KAT6B/MSC/PIGA/TNFSF11/NUP35/MPC1/VEGFC/NFYB/PTP4A3/SIRT1	40
BP	GO:1990830	cellular response to leukemia inhibitory factor	40/4749	96/18670	0.0003618	0.007991	0.006501	ICAM1/KLF4/TFRC/MYBL2/PFKP/TLE4/PML/RFX2/HK2/TRIM25/SBNO2/SMAD7/SOCS3/GLDC/ARID5B/CTH/KDM5B/B3GNT2/EED/MRAS/PARP16/NCL/EFHC2/ILDR1/MRPL15/SLC25A5/INA/DTX1/PADI2/SYNGR1/KAT6B/MSC/PIGA/TNFSF11/NUP35/MPC1/VEGFC/NFYB/PTP4A3/SIRT1	40
BP	GO:0032092	positive regulation of protein binding	39/4749	93/18670	0.0003645	0.008005	0.006512	TIRAP/CDK5/ANXA2P2/LGALS3/MMP9/SYAP1/PLK2/DERL1/SPPL3/ANXA2/DTX3L/TIAM1/CTHRC1/ARRB1/HIP1R/TCF7L2/STK3/PLXND1/FLOT1/VTN/PPP2CA/TRAF4/FKBP1A/LRP1/PLCL2/PARK7/EPB41L5/SPON1/STPG1/RAPGEF2/TRAF2/RIPK2/EPB41/ARF6/RPL11/RALB/CRBN/ADD2/TRIB3	39
BP	GO:2001242	regulation of intrinsic apoptotic signaling pathway	62/4749	165/18670	0.000366	0.008005	0.006512	PPIF/SKIL/SGMS1/PLAUR/ZNF385A/DAPK2/MCL1/ENO1/DNAJA1/MMP9/SFPQ/SERINC3/HSPA1A/RRM2B/NOL3/BAX/PTPN1/PMAIP1/GPX1/PLAGL2/SYVN1/MSX1/RIPK3/SRC/SNAI1/ARHGEF2/RPL26/BMF/CLU/UBB/CD74/URI1/HERPUD1/RPS3/BID/PINK1/CYLD/BCAP31/FIGNL1/BCL2A1/TAF9B/MUC1/DDIT3/BDKRB2/STYXL1/PARK7/BCL2L12/CD44/TXNDC12/BCL2L1/PTPMT1/PIAS4/EIF2AK3/S100A8/NUPR1/RPL11/VNN1/NDUFA13/PDX1/BAD/RAD9A/SIRT1	62
BP	GO:0051304	chromosome separation	38/4749	90/18670	0.0003661	0.008005	0.006512	ESPL1/CENPF/AURKB/BUB1B/TTK/CDT1/TOP2A/TOP3A/TRIP13/CDC20/PTTG1/DLGAP5/BUB1/TACC3/NCAPD2/CDC6/PPP2R1A/PLK1/CCNB1/CENPE/FBXO5/NUMA1/NDC80/DIS3L2/HELQ/RECQL5/NCAPH/ANAPC11/USP44/ANAPC1/XRCC3/EME1/NCAPH2/MAD2L2/KLHL22/APC/ATM/DUSP1	38
BP	GO:0032872	regulation of stress-activated MAPK cascade	84/4749	237/18670	0.0003691	0.008042	0.006543	IL1B/PBK/VEGFA/FOXM1/DUSP10/GADD45G/RASSF2/EPHB1/IL1RN/SIRPA/TIRAP/DNAJA1/SEMA4C/HMGB1/TNF/FGD2/TLR4/PTPN1/GADD45A/CARD9/NBR1/PDCD4/MAP3K6/ARHGEF5/TIAM1/SDCBP/MAP3K2/DVL3/IGF1R/PAK1/RPS3/FKTN/FOXO1/TNFRSF19/FAS/MAP3K5/PINK1/EZR/CYLD/STK3/NRK/DUSP22/NOD2/TRAF4/MAP3K11/MID1/DTNBP1/IL26/TAOK3/WNT7A/TLR6/FZD8/RAPGEF1/STK25/PHLPP1/MAP3K3/ZC3H12A/MINK1/MAP2K4/FLT4/EMC10/SFRP1/TRAF2/MAP4K1/ERN1/RIPK2/IL36A/AIDA/TRAF6/BIRC7/MIR181D/TNFSF11/EDAR/FZD5/NCF1/ZNF675/MAP3K9/PLCB1/MAPK1/NCOR1/PRDX1/IL37/PJA2/DUSP1	84
BP	GO:0007254	JNK cascade	77/4749	214/18670	0.0003773	0.008181	0.006656	IL1B/DUSP10/GADD45G/TRIB1/RASSF2/EPHB1/IL1RN/SIRPA/TIRAP/DNAJA1/HMGB1/TNF/FGD2/TLR4/PTPN1/GADD45A/CARD9/PDCD4/MAP3K6/ARHGEF5/TIAM1/SDCBP/MAP3K2/PTGER4/DVL3/UBB/IGF1R/PAK1/UBE2N/RPS3/FKTN/RPS27A/TNFRSF19/CASR/MAP3K5/PINK1/CYLD/STK3/NRK/UBA52/DUSP22/NOD2/TRAF4/MAP3K11/IRAK1/DTNBP1/TAOK3/WNT7A/TLR6/FZD8/RAPGEF1/SH2D3A/TAB1/SH2D3C/PHLPP1/MINK1/MAP2K4/FLT4/SFRP1/TRAF2/MAP4K1/ERN1/RIPK2/IL36A/AIDA/TRAF6/BIRC7/TNFSF11/EDAR/FZD5/NCF1/ZNF675/MAP3K9/PLCB1/NCOR1/IL37/PJA2	77
BP	GO:0044380	protein localization to cytoskeleton	26/4749	55/18670	0.000378	0.008181	0.006656	ANLN/STIL/FAM83D/TTK/AURKA/KIF20B/SPAG5/RTKN/MAPRE2/NUMA1/HTR2A/DVL1/KLHL21/MID1/MID2/MARK4/PIBF1/CEP192/NSFL1C/MAP1A/CEP72/APC/CHAMP1/PARD6A/MCPH1/NUP62	26
BP	GO:0042107	cytokine metabolic process	49/4749	124/18670	0.0003847	0.008297	0.00675	EGR1/EBI3/IL1B/IRF7/CD86/IL18/CD276/IL21/IL10/KLF4/CD80/IRF4/BCL3/TLR8/TIRAP/CLEC7A/TNF/ZFP36/TNFRSF8/CYBB/TLR4/FOXP3/CARD9/STAT3/CCR2/HMOX1/MAP2K3/CD74/PTPRC/SIGIRR/MAST2/LAG3/TLR6/CEBPB/IRF3/CD3E/CARD11/GHRL/IL4/MAPKAPK2/TYROBP/TRAF6/PCSK5/ASB1/GLMN/ZFPM1/GATA3/PTAFR/CX3CR1	49
BP	GO:0051783	regulation of nuclear division	69/4749	188/18670	0.0003899	0.008382	0.006819	ESPL1/CENPF/LIF/AURKB/PKMYT1/IL1B/ANLN/CDCA5/UBE2C/BUB1B/TTK/MKI67/CDT1/AURKA/KIF20B/NEK2/TRIP13/CDC20/PTTG1/DLGAP5/NUSAP1/BUB1/TACC3/CDC6/SMC3/CHMP2B/FBXO43/HSPA1A/UBE2B/KIF11/PLK1/CDC25C/MSX1/CCNB1/CENPE/FBXO5/NUMA1/NDC80/PDXP/PHIP/TOM1L2/ANAPC11/CHEK1/USP44/RCC1/ANAPC1/XRCC3/SIRT2/CHMP1A/CDC14B/NSFL1C/MAD2L2/CHMP2A/INSR/KLHL22/FGF8/APC/SMC1A/MAP9/PPP1R9B/ATM/SMC5/PLCB1/TGFB1/TOM1L1/CEP97/PDGFB/NUP62/DUSP1	69
BP	GO:0045591	positive regulation of regulatory T cell differentiation	10/4749	14/18670	0.0003962	0.00846	0.006882	DUSP10/BCL6/LGALS9/BTN2A2/FOXP3/HLA-G/LILRB4/LILRB2/CD46/TGFB1	10
BP	GO:0070672	response to interleukin-15	10/4749	14/18670	0.0003962	0.00846	0.006882	IL2RB/STAT3/IL2RG/IL15RA/ACSL4/STAT5A/PLCB1/JAK3/SHC1/JAK1	10
BP	GO:0045841	negative regulation of mitotic metaphase/anaphase transition	19/4749	36/18670	0.000405	0.00862	0.007013	CENPF/AURKB/BUB1B/TTK/CDT1/TRIP13/CDC20/BUB1/PLK1/CCNB1/FBXO5/NDC80/USP44/XRCC3/MAD2L2/KLHL22/APC/ATM/DUSP1	19
BP	GO:0009108	coenzyme biosynthetic process	91/4749	261/18670	0.0004074	0.008641	0.00703	MTHFD1L/TPI1/PDPR/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/PTGIS/ENO1/PGAM1/PFKP/GPI/CBFA2T3/SIRT6/HK2/SLC25A1/NUP98/FDXR/PPTC7/ENTPD5/TPK1/TECR/STAT3/SCD/PGM2L1/PKM/ALDOC/OGDH/HTR2A/PDHB/PPT1/MTHFS/PFKFB4/NUP153/ACSL1/PDHX/DHFR/HSD17B8/NAMPT/LIAS/DDIT4/NADK/GALK1/MTHFD1/PARP16/PFKFB2/DLAT/NUP88/ENO3/PRKAG2/ELOVL7/POM121C/NUP205/RAE1/ELOVL1/IDO1/MOCS1/NUP50/ACSL4/NDUFA9/METTL16/ALDOA/PANK4/COQ10A/ACACB/RNLS/ACSS1/FASN/INSR/NUPR1/NUP93/PFKL/NFS1/ALDOB/NUP35/SPR/PANK1/AAAS/MPC1/NMNAT1/GSTZ1/NMNAT3/NUP62/SLC25A16/AKR1A1/P2RX7/SEH1L/NCOR1/ASPDH	91
BP	GO:0006096	glycolytic process	46/4749	115/18670	0.0004158	0.008791	0.007152	TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/GPI/CBFA2T3/SIRT6/HK2/NUP98/ENTPD5/STAT3/PGM2L1/PKM/ALDOC/OGDH/HTR2A/PFKFB4/NUP153/DDIT4/GALK1/PFKFB2/NUP88/ENO3/PRKAG2/POM121C/NUP205/RAE1/NUP50/ALDOA/INSR/NUPR1/NUP93/PFKL/ALDOB/NUP35/AAAS/NUP62/P2RX7/SEH1L/NCOR1	46
BP	GO:0045862	positive regulation of proteolysis	121/4749	363/18670	0.000419	0.008829	0.007183	IL1B/RNF144A/FURIN/GRAMD4/PPARG/NLRP3/CASP9/AURKA/TRIB1/TTBK1/CTSH/GRN/PERP/ENO1/CLEC7A/HIP1/PRELID1/LGALS9/PML/SNX9/HMGB1/CBFA2T3/TNF/GSN/HSPA1A/PLK2/ECSCR/BAX/PLK1/TIMM17A/DET1/PMAIP1/ASPH/CARD9/STAT3/SMAD7/ASTL/DAP/CYFIP2/SRC/P2RX1/CFLAR/ARRB1/VCP/CLU/MAPK12/BCL2L13/MAGEF1/HERPUD1/RPS3/HIP1R/PDCD5/RNF40/CCK/SGTA/SMURF1/FAS/BID/TNFRSF10B/MAP3K5/PINK1/PIAS1/BCAP31/KHDC1/DVL1/BAK1/TANK/GBA/CTSD/RCN3/SUMO1/CASP8AP2/RNF19B/FMR1/SPON1/ACVR1C/FBXW11/RAD23A/SNX33/EDEM2/ACER2/USP5/IST1/ZC3H12A/KLKB1/GSK3A/PSME2/BTRC/IFI16/UBQLN2/BAG2/DAPK1/TRAF2/SIRT2/EIF2AK3/S100A8/ST18/F3/ZFAND2A/MYH9/CIDEB/RIPK2/TNFRSF1B/F2R/TNFSF10/RNF139/GCLC/AKIRIN2/NUPR1/OSBPL7/C6/CARD8/WDR48/PSMD10/NDUFA13/DNAJB2/ADAM9/BAD/FYN/TRIB3/SIRT1	121
BP	GO:0006302	double-strand break repair	87/4749	248/18670	0.0004303	0.009037	0.007352	TWIST1/CDCA5/FOXM1/RBBP8/TRIP13/ESCO2/MCM4/MCM5/SFPQ/RAD54L/PML/SIRT6/BRCA2/AP5S1/ZSWIM7/FEN1/RAD51/RAD51AP1/NUDT16/PARPBP/MCM2/RMI2/PARP2/DTX3L/TONSL/TP53BP1/VCP/CDC45/GINS2/DMC1/POLQ/RFWD3/MAGEF1/GINS4/XRCC6/UBE2N/MCM7/HELQ/TFIP11/FIGNL1/TIMELESS/RECQL5/RNF8/SUMO1/BRCC3/MCM3/REC8/CHEK1/APLF/RECQL4/SAMHD1/UVRAG/POLM/XRCC3/XRCC1/EME1/PRPF19/SFR1/WRAP53/AUNIP/DDX11/PIAS4/MDC1/DNA2/NHEJ1/MAD2L2/HELB/CHEK2/RAD52/POLN/MTA1/OGG1/ATM/NUCKS1/WDR48/WRN/SMC5/FAN1/HERC2/RNF138/WAS/MGMT/GGN/ERCC1/BARD1/RNF168/RAD54B	87
BP	GO:0002204	somatic recombination of immunoglobulin genes involved in immune response	23/4749	47/18670	0.000436	0.009053	0.007365	IL10/BATF/EXO1/BCL6/TNFSF4/TFRC/MSH6/FOXP3/SWAP70/CCR6/TP53BP1/PTPRC/SUPT6H/AICDA/IL27RA/RNF8/APLF/TNFSF13/IL4/MAD2L2/TGFB1/ERCC1/RNF168	23
BP	GO:0002208	somatic diversification of immunoglobulins involved in immune response	23/4749	47/18670	0.000436	0.009053	0.007365	IL10/BATF/EXO1/BCL6/TNFSF4/TFRC/MSH6/FOXP3/SWAP70/CCR6/TP53BP1/PTPRC/SUPT6H/AICDA/IL27RA/RNF8/APLF/TNFSF13/IL4/MAD2L2/TGFB1/ERCC1/RNF168	23
BP	GO:0045190	isotype switching	23/4749	47/18670	0.000436	0.009053	0.007365	IL10/BATF/EXO1/BCL6/TNFSF4/TFRC/MSH6/FOXP3/SWAP70/CCR6/TP53BP1/PTPRC/SUPT6H/AICDA/IL27RA/RNF8/APLF/TNFSF13/IL4/MAD2L2/TGFB1/ERCC1/RNF168	23
BP	GO:0035794	positive regulation of mitochondrial membrane permeability	29/4749	64/18670	0.0004367	0.009053	0.007365	PPIF/TP73/BNIP3L/YWHAH/YWHAE/TP63/YWHAZ/E2F1/HSPA1A/BAX/PMAIP1/MOAP1/SFN/BMF/HIP1R/EYA2/NMT1/BID/TFDP2/BAK1/YWHAQ/SLC25A5/STPG1/ZNF205/GSK3A/RHOT2/FZD9/SPG7/BAD	29
BP	GO:0051383	kinetochore organization	13/4749	21/18670	0.000443	0.009154	0.007447	CENPF/CENPA/CDT1/CENPW/NUF2/CENPE/NDC80/CENPT/CENPN/SENP6/POGZ/TRAPPC12/CENPK	13
BP	GO:0042108	positive regulation of cytokine biosynthetic process	30/4749	67/18670	0.0004503	0.009273	0.007544	EGR1/EBI3/IL1B/CD86/CD276/IL21/CD80/IRF4/BCL3/TLR8/TIRAP/CLEC7A/TNF/TNFRSF8/CYBB/TLR4/STAT3/CCR2/HMOX1/CD74/PTPRC/TLR6/CD3E/CARD11/MAPKAPK2/TYROBP/TRAF6/GLMN/ZFPM1/PTAFR	30
BP	GO:0002724	regulation of T cell cytokine production	17/4749	31/18670	0.0004516	0.009273	0.007544	IL1B/IL18/NLRP3/IL1R1/TNFSF4/FOXP3/RSAD2/SMAD7/CCR2/TRPM4/ARG1/IL18R1/TRAF2/TNFRSF1B/TRAF6/FZD5/GATA3	17
BP	GO:0002312	B cell activation involved in immune response	32/4749	73/18670	0.0004696	0.00949	0.007721	IL10/BATF/EXO1/BCL3/BCL6/TNFSF4/TFRC/MSH6/TLR4/FOXP3/ITM2A/ITFG2/SWAP70/CCR6/TP53BP1/LGALS1/CD180/PTPRC/SUPT6H/AICDA/IL27RA/PLCL2/RNF8/CD19/APLF/TNFSF13/IL4/MAD2L2/DLL1/TGFB1/ERCC1/RNF168	32
BP	GO:0032945	negative regulation of mononuclear cell proliferation	32/4749	73/18670	0.0004696	0.00949	0.007721	CD86/SDC4/IL10/CD80/PTPN6/GPNMB/LGALS9/IL2RA/BTN2A2/TNFRSF21/FOXP3/CTLA4/HLA-G/BTK/HAVCR2/CLEC4G/LILRB2/ARG1/TNFRSF13B/MNDA/ERBB2/CEBPB/IDO1/SOX11/PDCD1LG2/DLG5/PRNP/TYROBP/ATM/TGFB1/GLMN/LRRC32	32
BP	GO:0050672	negative regulation of lymphocyte proliferation	32/4749	73/18670	0.0004696	0.00949	0.007721	CD86/SDC4/IL10/CD80/PTPN6/GPNMB/LGALS9/IL2RA/BTN2A2/TNFRSF21/FOXP3/CTLA4/HLA-G/BTK/HAVCR2/CLEC4G/LILRB2/ARG1/TNFRSF13B/MNDA/ERBB2/CEBPB/IDO1/SOX11/PDCD1LG2/DLG5/PRNP/TYROBP/ATM/TGFB1/GLMN/LRRC32	32
BP	GO:0032506	cytokinetic process	20/4749	39/18670	0.0004706	0.00949	0.007721	KIF20A/AURKB/ANLN/KIF23/CEP55/KIF20B/RACGAP1/RTKN/SNX9/CHMP2B/ECT2/SNX33/CHMP1A/MYH9/CHMP2A/MITD1/ALKBH4/NUP62/CHMP3/KLHDC8B	20
BP	GO:2000816	negative regulation of mitotic sister chromatid separation	20/4749	39/18670	0.0004706	0.00949	0.007721	CENPF/AURKB/BUB1B/TTK/CDT1/TRIP13/CDC20/PTTG1/BUB1/PLK1/CCNB1/FBXO5/NDC80/USP44/XRCC3/MAD2L2/KLHL22/APC/ATM/DUSP1	20
BP	GO:0051231	spindle elongation	8/4749	10/18670	0.0004711	0.00949	0.007721	AURKB/KIF4A/KIF23/RACGAP1/PPP2R1A/NUMA1/KIF4B/PRC1	8
BP	GO:0016052	carbohydrate catabolic process	72/4749	199/18670	0.0004775	0.00959	0.007802	NAGA/TPI1/GK/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/NEU4/GLB1/ENO1/PGAM1/PFKP/GPI/CBFA2T3/SIRT6/PPP1CB/HK2/GM2A/NUP98/NEU1/ENTPD5/STAT3/PGM2L1/PKM/ALDOC/OGDH/HTR2A/PYGM/PFKFB4/MAN2B1/NUP153/GALK2/DDIT4/ENOSF1/GALK1/PFKFB2/NUP88/ENO3/PRKAG2/GALM/POM121C/NUP205/RAE1/NUP50/GSK3A/PHKG2/ALDOA/NEU3/FUT6/RPE/INSR/NUPR1/HEXB/GALT/GUSB/NUP93/MANBA/PFKL/ALDOB/NUP35/PGD/AAAS/NUP62/AKR1A1/P2RX7/SEH1L/NCOR1/BAD/PPP1R3B/AMY2A	72
BP	GO:0021915	neural tube development	60/4749	160/18670	0.000479	0.00959	0.007802	TWIST1/NOTCH1/SDC4/STIL/MTHFD1L/LUZP1/KIF20B/PLXNB2/PTCH1/GPR161/ST14/SEMA4C/FOXB1/SKI/DCHS1/ALX1/CTHRC1/DVL3/FZD6/PTK7/KAT2A/PKD2/SSBP3/AMBRA1/LMO4/ARHGAP35/SPINT1/STK3/LIAS/SALL4/VASP/IFT122/CFL1/TCTN1/DVL1/MTHFD1/SCRIB/IFT172/RALA/GDF7/ARID1A/FKBP8/WDR19/SOX11/FERD3L/TMEM107/SHROOM3/SFRP1/ADM/ZFP36L1/LRP6/PRKACB/TRAF6/FGF8/PLOD3/MED12/SALL2/TGFB1/GLMN/RARA	60
BP	GO:0009161	ribonucleoside monophosphate metabolic process	118/4749	354/18670	0.00049	0.00978	0.007956	PPIF/CDK1/TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/COX8A/GPI/CBFA2T3/SIRT6/DHODH/HK2/HSPA1A/NUP98/CTNS/TJP2/SLC25A23/ENTPD5/ABCD1/DNAJC30/STAT3/TSPO/FXN/CCNB1/PFAS/PGM2L1/PKM/AK5/ALDOC/VCP/OGDH/HTR2A/NDUFB11/COX6A1/PFKFB4/HPRT1/UQCRC1/SLC25A25/NUP153/FAM20C/AK3/NDUFB8/LHPP/ATP1B1/BID/PINK1/UPRT/DDIT4/NADK/ATP6V1A/VPS9D1/FIGNL1/GALK1/PFKFB2/NDUFS1/NUP88/ENO3/AMPD2/PRKAG2/NDUFS7/MYH7/PARK7/POM121C/NDUFB10/AK4/MYH4/NUP205/RAE1/NUP50/NDUFC1/APRT/IMPDH1/NDUFA9/NUDT3/COX4I1/LRGUK/UQCR11/CARD11/ALDOA/GUK1/AMPD3/IL4/ISCU/NDUFA12/NT5E/AK1/CMPK1/UCK2/INSR/NUPR1/SPHK2/PRPS1/NUP93/PFKL/ALDOB/NUP35/AAAS/OLA1/TAZ/AK2/NDUFA4/MYH6/NDUFB2/TGFB1/NT5C2/NDUFA13/NMNAT1/NUP62/P2RX7/SEH1L/NCOR1/BAD	118
BP	GO:0002697	regulation of immune effector process	148/4749	458/18670	0.0004982	0.009911	0.008063	IL1B/CD86/CD1E/IL18/IL21/NR4A3/NLRP3/DUSP10/IL10/IL1R1/FES/IFIT1/TSPAN32/CD80/PTPN6/IRF4/BCL6/HK1/TREX1/GRN/TNFSF4/TFRC/MZB1/LGALS3/CEACAM1/LGALS9/ULBP2/GPI/HMGB1/PQBP1/TNF/TNFRSF4/SEMA7A/PROS1/IL2RA/CD1A/TLR4/FOXP3/GAB2/RAET1E/CD1C/MMP12/IL4R/RSAD2/SMAD7/FFAR2/RIPK3/CCR2/HLA-H/C1QB/HMOX1/DTX3L/SEC14L1/HLA-G/TP53BP1/SH2D1A/BTK/CLU/CD1B/BST2/HAVCR2/TGFB3/CD74/CD177/TRIL/CD1D/FFAR3/CLEC4G/HLX/IRAK3/NPLOC4/PGLYRP3/CFHR4/PTPRC/RPS19/TRPM4/HLA-E/CD47/DUSP22/A2M/SUPT6H/VTN/TRIM44/MICA/NOD2/IL12RB1/IL27RA/ARG1/CD19/LAG3/CADM1/LTA/IL18R1/CD46/RNF216/RAPGEF1/UNC13D/C3AR1/CR2/SUSD4/CRK/RAC2/IL7R/APLF/HLA-DMB/CFI/ZC3H12A/RABGEF1/BIRC3/SERPING1/IL13/CFB/TRAF2/LAMP1/CFHR1/TNFSF13/IL4/RIPK2/TNFRSF1B/ULBP1/FER/C1QA/C1R/MAD2L2/C1QBP/KLK5/TRAF6/SPHK2/C6/BCR/TSPAN6/STAT1/FZD5/HTRA1/ANKRD17/TGFB1/WAS/JAK3/ZCCHC3/RARA/KLRK1/CD96/GATA3/PTAFR/USP17L2/P2RX7/TRIM15/IL23A	148
BP	GO:0070302	regulation of stress-activated protein kinase signaling cascade	84/4749	239/18670	0.0004999	0.009915	0.008066	IL1B/PBK/VEGFA/FOXM1/DUSP10/GADD45G/RASSF2/EPHB1/IL1RN/SIRPA/TIRAP/DNAJA1/SEMA4C/HMGB1/TNF/FGD2/TLR4/PTPN1/GADD45A/CARD9/NBR1/PDCD4/MAP3K6/ARHGEF5/TIAM1/SDCBP/MAP3K2/DVL3/IGF1R/PAK1/RPS3/FKTN/FOXO1/TNFRSF19/FAS/MAP3K5/PINK1/EZR/CYLD/STK3/NRK/DUSP22/NOD2/TRAF4/MAP3K11/MID1/DTNBP1/IL26/TAOK3/WNT7A/TLR6/FZD8/RAPGEF1/STK25/PHLPP1/MAP3K3/ZC3H12A/MINK1/MAP2K4/FLT4/EMC10/SFRP1/TRAF2/MAP4K1/ERN1/RIPK2/IL36A/AIDA/TRAF6/BIRC7/MIR181D/TNFSF11/EDAR/FZD5/NCF1/ZNF675/MAP3K9/PLCB1/MAPK1/NCOR1/PRDX1/IL37/PJA2/DUSP1	84
BP	GO:1903532	positive regulation of secretion by cell	131/4749	399/18670	0.000502	0.009926	0.008075	TWIST1/IL1B/MAPK11/SDC4/NLRP3/ADORA2A/CSF1R/IL10/ABCG1/RAC1/TLR8/IL17A/GAPDH/HK1/NMB/TNFSF4/CDK5/SPP1/LGALS9/GPI/MYH10/HMGB1/TNF/TNFRSF4/BLK/TLR4/NCS1/LILRA2/GAB2/MMP12/HYAL3/IL4R/SNF8/FFAR2/FRMD4A/FCN1/SRC/ABAT/SYT4/ARRB1/CCL3/SDCBP/ATP13A2/PTGER4/STAM/HAVCR2/C2CD2L/SRI/CD33/TGFB3/CD177/RAB3D/CCK/STXBP5/CASR/STX1B/SDC1/TCF7L2/PINK1/SPTBN1/EZR/TRPM4/CLASP2/NADK/HLA-E/AIF1/OXCT1/TLR2/KCNN4/PFKFB2/CD58/NOD2/PSMD9/LRP1/DTNBP1/IL26/OSM/HGS/CADM1/SIRT3/ILDR1/RAB27A/CNR1/NTSR1/C1QTNF3/UNC13D/IL17RC/PRKCE/TACR2/SOX11/IRF3/GLUD1/PAEP/LILRA5/IL13/CD2AP/LAMP1/IFNGR1/GHRL/CD34/RIPK2/MYOM1/F2R/SERP1/DOC2B/CLEC5A/P2RY1/CHMP2A/RAB15/ARF6/SPHK2/CACNB2/CARD8/PARD6A/TNFSF11/FZD5/PPARD/FFAR1/TGFB1/GLMN/TMF1/ADAM9/TRIM16/GATA3/PTAFR/PDX1/P2RX7/GIPR/SYBU/VEGFC/BAD	131
BP	GO:0042866	pyruvate biosynthetic process	47/4749	119/18670	0.0005071	0.009995	0.008132	TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/GPI/CBFA2T3/SIRT6/HK2/NUP98/ENTPD5/SDS/STAT3/PGM2L1/PKM/ALDOC/OGDH/HTR2A/PFKFB4/NUP153/DDIT4/GALK1/PFKFB2/NUP88/ENO3/PRKAG2/POM121C/NUP205/RAE1/NUP50/ALDOA/INSR/NUPR1/NUP93/PFKL/ALDOB/NUP35/AAAS/NUP62/P2RX7/SEH1L/NCOR1	47
BP	GO:1990845	adaptive thermogenesis	58/4749	154/18670	0.0005194	0.01021	0.008304	G0S2/VEGFA/NOTCH1/PLAC8/IL18/GADD45G/IRF4/PCTP/THRA/ACOT11/SIRT6/TLR4/ARRDC3/WNT10B/IL4R/SORL1/CCR2/SCD/HCRT/PPARGC1B/TFE3/FABP5/GNAS/IGF1R/RBPJ/ATF4/PER2/MAP2K6/ACSL1/PRDM16/PRKAB2/KSR2/TLE3/CNOT3/ADIPOR2/ADIPOR1/PLCL2/DDIT3/IL18R1/ACVR2B/TSHR/EPAS1/CEBPB/ARNTL/ALMS1/IL13/GHRL/IP6K1/ADIPOQ/IL4/BSCL2/PTH2R/LNPEP/APC/ID1/PGAM5/OMA1/LPIN1	58
BP	GO:0006757	ATP generation from ADP	46/4749	116/18670	0.0005212	0.01021	0.008307	TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/GPI/CBFA2T3/SIRT6/HK2/NUP98/ENTPD5/STAT3/PGM2L1/PKM/ALDOC/OGDH/HTR2A/PFKFB4/NUP153/DDIT4/GALK1/PFKFB2/NUP88/ENO3/PRKAG2/POM121C/NUP205/RAE1/NUP50/ALDOA/INSR/NUPR1/NUP93/PFKL/ALDOB/NUP35/AAAS/NUP62/P2RX7/SEH1L/NCOR1	46
BP	GO:0097028	dendritic cell differentiation	21/4749	42/18670	0.0005317	0.01038	0.008445	RELB/CSF2/BATF/IRF4/SPI1/LGALS9/UBD/HMGB1/ZBTB46/HLA-G/AXL/RBPJ/FLT3/LILRB2/AZI2/CEBPB/TMEM176B/IL4/DHRS2/TRAF6/TGFB1	21
BP	GO:0002381	immunoglobulin production involved in immunoglobulin mediated immune response	26/4749	56/18670	0.0005364	0.01038	0.008445	IL10/BATF/EXO1/BCL6/TREX1/TNFSF4/TFRC/MSH6/FOXP3/SWAP70/CCR6/TP53BP1/BTK/PTPRC/SUPT6H/AICDA/IL27RA/RNF8/APLF/TNFSF13/IL4/MAD2L2/POU2F2/TGFB1/ERCC1/RNF168	26
BP	GO:0032615	interleukin-12 production	26/4749	56/18670	0.0005364	0.01038	0.008445	MAPK11/IL10/ACP5/TLR8/TIRAP/TNFSF4/CLEC7A/LGALS9/HMGB1/IRF5/TLR4/HLA-G/TIGIT/IRAK3/CD47/TLR2/MAST2/PIBF1/IDO1/LILRA5/RIPK2/C1QBP/TRAF6/PLCB1/JAK3/IL23A	26
BP	GO:0044784	metaphase/anaphase transition of cell cycle	26/4749	56/18670	0.0005364	0.01038	0.008445	ESPL1/CENPF/AURKB/BUB1B/TTK/CDT1/TRIP13/CDC20/DLGAP5/BUB1/TACC3/CDC6/PLK1/CCNB1/CENPE/FBXO5/NDC80/ANAPC11/USP44/ANAPC1/XRCC3/MAD2L2/KLHL22/APC/ATM/DUSP1	26
BP	GO:1903829	positive regulation of cellular protein localization	109/4749	324/18670	0.0005413	0.01041	0.008467	LIF/IL1B/GPSM2/GTSE1/TP73/CDK1/CDT1/SQSTM1/ITGA3/KIF20B/YWHAH/CAMK1/CDK5/LGALS3/YWHAE/TP63/RBM22/YWHAZ/TNF/E2F1/AKAP5/PLK1/PMAIP1/RANGRF/SORL1/USP36/SRC/SAE1/TENM1/DTX3L/SEC16A/B3GAT3/NUMA1/RHOG/NDC80/SFN/CLIP3/PLS1/GLIS2/PAK1/BAP1/PTPN9/PDCD5/CCT5/NMT1/HPS4/LRP4/TCF7L2/BID/PINK1/SPTBN1/EZR/CYLD/BCAP31/PRKCI/STAC3/TFDP2/LRP1/STAC/TMEM30A/GNL3/YWHAQ/CHP1/PARK7/EMD/EFCAB7/ERBB2/MARK4/MCRS1/OAZ2/SYT11/PRKCE/RAC2/ECT2/SNX33/EDEM2/EPB41L2/ZC3H12A/BAG3/GSK3A/RHOU/UBL5/WRAP53/CD2AP/EIF2AK3/PRNP/TYROBP/EPB41/HSPA1L/MAP1A/ARF6/APC/OAZ1/PARD6A/FZD5/STOM/ZFAND1/RUFY3/TGFB1/BCAS3/CNST/TRAPPC12/MAPK1/NUP62/SESN2/SREBF2/BAD/FYN/CCT3	109
BP	GO:0007094	mitotic spindle assembly checkpoint	18/4749	34/18670	0.0005459	0.01041	0.008467	CENPF/AURKB/BUB1B/TTK/CDT1/TRIP13/CDC20/BUB1/PLK1/CCNB1/NDC80/USP44/XRCC3/MAD2L2/KLHL22/APC/ATM/DUSP1	18
BP	GO:0031577	spindle checkpoint	18/4749	34/18670	0.0005459	0.01041	0.008467	CENPF/AURKB/BUB1B/TTK/CDT1/TRIP13/CDC20/BUB1/PLK1/CCNB1/NDC80/USP44/XRCC3/MAD2L2/KLHL22/APC/ATM/DUSP1	18
BP	GO:0071173	spindle assembly checkpoint	18/4749	34/18670	0.0005459	0.01041	0.008467	CENPF/AURKB/BUB1B/TTK/CDT1/TRIP13/CDC20/BUB1/PLK1/CCNB1/NDC80/USP44/XRCC3/MAD2L2/KLHL22/APC/ATM/DUSP1	18
BP	GO:0071174	mitotic spindle checkpoint	18/4749	34/18670	0.0005459	0.01041	0.008467	CENPF/AURKB/BUB1B/TTK/CDT1/TRIP13/CDC20/BUB1/PLK1/CCNB1/NDC80/USP44/XRCC3/MAD2L2/KLHL22/APC/ATM/DUSP1	18
BP	GO:0009152	purine ribonucleotide biosynthetic process	96/4749	280/18670	0.0005531	0.01047	0.008518	TPI1/PDPR/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/GPI/CBFA2T3/SIRT6/HK2/SLC25A1/NUP98/ENTPD5/TECR/DNAJC30/STAT3/ADCY4/PFAS/SCD/PGM2L1/PKM/AK5/ALDOC/VCP/OGDH/HTR2A/PDHB/PPT1/PFKFB4/HPRT1/ADCY6/NUP153/ACSL1/PDHX/AK3/NME4/PINK1/HSD17B8/DDIT4/SLC35B2/VPS9D1/GALK1/PFKFB2/DLAT/NUP88/ENO3/AMPD2/PRKAG2/NME3/ELOVL7/POM121C/AK4/NUP205/RAE1/ELOVL1/ADCY3/NUP50/APRT/IMPDH1/ACSL4/ALDOA/GUK1/AMPD3/IL4/PANK4/ACACB/AK1/ACSS1/FASN/INSR/NUPR1/ADCY9/SPHK2/NUP93/PFKL/PAPSS2/ALDOB/NUP35/NME9/PANK1/AAAS/TAZ/AK2/TGFB1/MPC1/GSTZ1/NUP62/P2RX7/SEH1L/NCOR1/NME2	96
BP	GO:0009141	nucleoside triphosphate metabolic process	120/4749	362/18670	0.0005609	0.01047	0.008518	PPIF/CDK1/TPI1/DCTPP1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/TYMS/COX8A/GPI/CBFA2T3/SIRT6/HK2/HSPA1A/RRM2B/NUP98/CTNS/SLC25A23/ENTPD5/CMPK2/ABCD1/DNAJC30/STAT3/TSPO/FXN/CCNB1/DTYMK/NUDT16/NUDT1/PGM2L1/PKM/AK5/ALDOC/VCP/OGDH/HTR2A/NDUFB11/COX6A1/PFKFB4/UQCRC1/SLC25A25/NUP153/FAM20C/AK3/NDUFB8/NME4/ATP1B1/BID/PINK1/DDIT4/NADK/ATP6V1A/VPS9D1/FIGNL1/GALK1/PFKFB2/NDUFS1/NUP88/ENO3/PRKAG2/NME3/NDUFS7/MYH7/PARK7/POM121C/NDUFB10/AK4/MYH4/NUP205/RAE1/MOCS1/NUP50/NDUFC1/SAMHD1/IMPDH1/NDUFA9/COX4I1/UQCR11/RAB23/ALDOA/GUK1/AMPD3/IL4/ISCU/NDUFA12/AK1/CMPK1/CTPS2/UCK2/INSR/NUPR1/SPHK2/NUP93/PFKL/NFS1/ALDOB/NUP35/NME9/AAAS/OLA1/TAZ/AK2/NDUFA4/MYH6/NDUFB2/TGFB1/NDUFA13/NMNAT1/NUP62/P2RX7/SEH1L/NCOR1/BAD/NME2	120
BP	GO:0045824	negative regulation of innate immune response	27/4749	59/18670	0.0005612	0.01047	0.008518	TYRO3/PPARG/DUSP10/TREX1/GRN/CEACAM1/LGALS9/MMP12/PARP14/HLA-G/HAVCR2/TRAFD1/IRAK3/RPS19/HLA-E/A2M/SCRIB/MICA/ARG1/CRK/NLRC3/SAMHD1/SERPING1/CNOT7/YTHDF3/IFI16/CD96	27
BP	GO:0072413	signal transduction involved in mitotic cell cycle checkpoint	27/4749	59/18670	0.0005612	0.01047	0.008518	GTSE1/E2F7/E2F8/CDK1/CDKN1A/AURKA/ZNF385A/PML/E2F1/PLK2/BAX/CDC25C/GADD45A/CCNB1/SFN/RPL26/CDK2/CARM1/CNOT3/TFDP2/MUC1/MDM4/RBL2/CNOT7/GML/CHEK2/ATM	27
BP	GO:1902402	signal transduction involved in mitotic DNA damage checkpoint	27/4749	59/18670	0.0005612	0.01047	0.008518	GTSE1/E2F7/E2F8/CDK1/CDKN1A/AURKA/ZNF385A/PML/E2F1/PLK2/BAX/CDC25C/GADD45A/CCNB1/SFN/RPL26/CDK2/CARM1/CNOT3/TFDP2/MUC1/MDM4/RBL2/CNOT7/GML/CHEK2/ATM	27
BP	GO:1902403	signal transduction involved in mitotic DNA integrity checkpoint	27/4749	59/18670	0.0005612	0.01047	0.008518	GTSE1/E2F7/E2F8/CDK1/CDKN1A/AURKA/ZNF385A/PML/E2F1/PLK2/BAX/CDC25C/GADD45A/CCNB1/SFN/RPL26/CDK2/CARM1/CNOT3/TFDP2/MUC1/MDM4/RBL2/CNOT7/GML/CHEK2/ATM	27
BP	GO:0007015	actin filament organization	131/4749	400/18670	0.000562	0.01047	0.008518	CDC42EP4/SDC4/FSCN1/PLEKHG2/ICAM1/NEDD9/CIT/MICAL1/SRF/MARCKS/HCK/RAC1/CYFIP1/ZYX/MSRB1/CORO1C/HIP1/NF2/FHOD1/SNX9/CAPZB/GSN/CTTN/MTOR/MYADM/BAG4/MICAL2/CDC42EP1/SWAP70/TMOD2/SRC/TENM1/PPARGC1B/ARHGEF5/TNFAIP1/RHOG/CAPG/ARHGEF2/CORO1B/ARRB1/PLS1/PTGER4/PDXP/TGFB3/WHAMMP3/PAK1/ADD3/PFN2/HIP1R/ARHGAP35/S1PR1/ARPC1B/PAK3/PREX1/PICK1/TMSB4Y/SPTBN1/EZR/CORO1A/STMN1/CLASP2/CD47/VASP/AIF1/TRIOBP/PRKCI/TWF2/LIMCH1/CFL1/ACTN4/DIAPH3/COTL1/SPTAN1/TPM2/S100A10/ARPC5/MKKS/MYBPC3/ARAP1/LIMK1/CAPZA1/SH3PXD2B/NRAP/SHROOM1/PRKCE/RAC2/ACTR3B/KANK3/WDR1/SAMD14/RHOF/MICAL3/ALMS1/RHOV/CORO7/SHROOM3/TMSB15A/RHOU/VILL/SFRP1/CD2AP/ALDOA/GHRL/KCTD13/MYOM1/FER/MAD2L2/PACSIN1/FAM171A1/ARF6/TPM1/ARHGAP18/AIF1L/ARHGAP17/PSTPIP2/SORBS3/PPP1R9B/WASF2/WHAMM/AP1AR/ID1/RUFY3/C15orf62/SEMA5A/CDC42/TCAP/WAS/MYBPC2/FMN1/ADD2/RAC3	131
BP	GO:0035148	tube formation	56/4749	148/18670	0.0005622	0.01047	0.008518	TWIST1/VEGFA/NOTCH1/SDC4/STIL/MTHFD1L/LUZP1/KIF20B/PLXNB2/PTCH1/ST14/SEMA4C/SKI/ALX1/TGM2/CTHRC1/DVL3/FZD6/PTK7/KAT2A/LMO4/ARHGAP35/SPINT1/STK3/LIAS/SALL4/VASP/IFT122/ATOH8/CFL1/TCTN1/DVL1/MTHFD1/SCRIB/IFT172/RALA/SOX8/GDF7/ARID1A/SOX11/SHROOM3/SFRP1/ADM/LRP6/DICER1/PRKACB/TRAF6/FGF8/MED12/EDAR/TGFB1/BCAS3/TCAP/GLMN/RARA/GATA3	56
BP	GO:1905818	regulation of chromosome separation	28/4749	62/18670	0.0005819	0.01081	0.008791	ESPL1/CENPF/AURKB/BUB1B/TTK/CDT1/TRIP13/CDC20/PTTG1/DLGAP5/BUB1/TACC3/CDC6/PLK1/CCNB1/CENPE/FBXO5/NUMA1/NDC80/ANAPC11/USP44/ANAPC1/XRCC3/MAD2L2/KLHL22/APC/ATM/DUSP1	28
BP	GO:0046632	alpha-beta T cell differentiation	41/4749	101/18670	0.0005856	0.01084	0.00882	CD86/IL18/RELB/NLRP3/BATF/CD83/CD80/IRF4/BCL3/BCL6/CBFB/TNFSF4/LGALS9/PRDM1/HMGB1/MTOR/FOXP3/STAT3/IL4R/RSAD2/SMAD7/PTGER4/LY9/HLX/SATB1/PNP/RORC/AP3D1/IL12RB1/IL18R1/ZC3H12A/ITK/RIPK2/PAX1/JAK3/RARA/ZAP70/ZFPM1/GATA3/RPL22/IL23A	41
BP	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	22/4749	45/18670	0.0005874	0.01084	0.008822	TP73/CDKN1A/PHLDA3/BCL3/ZNF385A/TP63/PML/BRCA2/RPL26/CD74/DDIT4/TAF9B/MUC1/BCL2L12/TOPORS/CD44/AEN/IFI16/CHEK2/NUPR1/SHISA5/SIRT1	22
BP	GO:0009156	ribonucleoside monophosphate biosynthetic process	71/4749	197/18670	0.0005903	0.01087	0.008841	TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/GPI/CBFA2T3/SIRT6/DHODH/HK2/NUP98/ENTPD5/DNAJC30/STAT3/PFAS/PGM2L1/PKM/AK5/ALDOC/VCP/OGDH/HTR2A/PFKFB4/HPRT1/NUP153/AK3/LHPP/PINK1/UPRT/DDIT4/VPS9D1/GALK1/PFKFB2/NUP88/ENO3/AMPD2/PRKAG2/POM121C/AK4/NUP205/RAE1/NUP50/APRT/IMPDH1/ALDOA/AMPD3/IL4/AK1/CMPK1/UCK2/INSR/NUPR1/SPHK2/PRPS1/NUP93/PFKL/ALDOB/NUP35/AAAS/TAZ/AK2/TGFB1/NUP62/P2RX7/SEH1L/NCOR1	71
BP	GO:0070555	response to interleukin-1	74/4749	207/18670	0.000601	0.01103	0.008974	EGR1/IL1B/MAPK11/ICAM1/SQSTM1/KLF2/IL1R1/CCL20/CCL3L3/IL17A/IL1RN/PTGIS/SIRPA/CCL22/GBP2/LGALS9/HYAL3/IL1R2/SRC/PSMD8/CCL3/UBB/PSMD1/PSMD2/UBE2N/PSMF1/UPF1/IRAK3/CCL2/RPS27A/TOLLIP/CCL17/PRKCA/CD47/PRKCI/CCL18/UBA52/NOD2/PSMD9/TANK/IRAK1/PSMA5/PSMB7/FBXW11/TAB1/NFKBIA/PSMD5/CEBPB/CYBA/MAP3K3/ZC3H12A/PSME2/BTRC/SFRP1/ST18/PSMB5/RIPK2/GCLC/PSMB4/TRAF6/CCL23/PSMA3/CCL7/ZNF675/PSMD10/PLCB1/CCL15/PSMB1/PSMD7/HAS2/PSMB3/PSMC5/TFPI/PSMD11	74
BP	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	39/4749	95/18670	0.0006061	0.01109	0.009024	CCNF/KIF14/AMN1/PSMD8/FBXL18/PSMD1/PSMD2/WWTR1/FBXL14/PSMF1/FBXO48/FBXO27/FBXO31/PSMD9/PSMA5/FBXL8/PSMB7/FBXW11/PSMD5/CUL5/RNF7/PSME2/BTRC/FBXL4/PSMB5/FBXO9/PSMB4/PSMA3/FBXL15/FBXL20/FBXO44/PSMD10/CUL4A/PSMB1/PSMD7/PSMB3/PSMC5/FBXO4/PSMD11	39
BP	GO:0002698	negative regulation of immune effector process	47/4749	120/18670	0.0006305	0.01151	0.009362	DUSP10/IL10/PTPN6/BCL6/GRN/TNFSF4/LGALS3/CEACAM1/LGALS9/TNF/IL2RA/FOXP3/IL4R/SMAD7/CCR2/HMOX1/SEC14L1/HLA-G/BST2/HAVCR2/TGFB3/CLEC4G/HLX/IRAK3/NPLOC4/PGLYRP3/PTPRC/RPS19/HLA-E/CD47/DUSP22/A2M/MICA/ARG1/CRK/IL7R/ZC3H12A/RABGEF1/SERPING1/FER/C1QBP/BCR/TSPAN6/HTRA1/TGFB1/JAK3/CD96	47
BP	GO:1902100	negative regulation of metaphase/anaphase transition of cell cycle	19/4749	37/18670	0.0006352	0.01156	0.009405	CENPF/AURKB/BUB1B/TTK/CDT1/TRIP13/CDC20/BUB1/PLK1/CCNB1/FBXO5/NDC80/USP44/XRCC3/MAD2L2/KLHL22/APC/ATM/DUSP1	19
BP	GO:0031667	response to nutrient levels	159/4749	499/18670	0.0006412	0.01161	0.009441	VDR/IL1B/CDKN1A/PPARG/GAS2L1/ITGA2/ICAM1/CD68/KANK2/CDKN2B/FES/NTRK1/SRF/BCL11A/LDHA/SLC16A1/DSC2/BBS2/SPP1/MTMR3/ATF3/TYMS/ASCL1/EIF4EBP1/HSPA5/SIRT6/ZFP36/DHODH/GSN/CYBB/CXCL10/MAP1LC3A/TRIM25/PMAIP1/MTOR/LDLR/GDAP1/ITFG2/TSPO/SORL1/PIM1/DAP/SRC/HCRT/HMOX1/P2RX1/MBD2/ATG9A/PKM/P2RY11/NENF/AMIGO1/PDXP/SLC22A3/P2RX6/USF2/KAT2A/HMGCL/ATF4/SLC25A25/NMRAL1/NUAK2/ASNS/PHEX/ACSL1/AMBRA1/NQO1/FOXO1/CCK/CASR/FAS/PICK1/MAP3K5/WDR24/NAMPT/TRPM4/C12orf66/ADIPOR2/OXCT1/ABCA1/ULK1/MKKS/NOD2/GBA/DDIT3/ARG1/LTA/GNAI2/CNR1/JUN/SLC38A2/CYP27B1/ACVR1C/MYBBP1A/KIAA1324/MPO/CYBA/PSPH/ZC3H12A/KLF10/TBXA2R/CD3E/ACSL4/NUCB2/COX4I1/IFI16/KRT20/BGLAP/NPRL3/SFRP1/ADM/PIK3C3/SIRT2/GHRL/EIF2AK3/ALDH3A1/ADIPOQ/TNFRSF11B/P2RX5/POR/SLC27A4/ACACB/GCLC/WDR45/NNT/P2RY1/MAX/RRP8/PIK3R4/STAT1/MBD1/RALB/GSS/OGG1/NPFF/PPARD/RRAGB/WRN/ATG7/TGFB1/BCAS3/MGMT/RARA/OMA1/MAPK1/CCND1/SETDB1/AMELX/LRP11/SESN2/PDX1/P2RX7/SEH1L/GIPR/SREBF2/ERCC1/FYN/SIRT1/NPRL2	159
BP	GO:0071453	cellular response to oxygen levels	82/4749	234/18670	0.0006413	0.01161	0.009441	EGR1/TWIST1/VEGFA/NOTCH1/PPARG/ICAM1/BNIP3L/CCNA2/ATP6V0D1/PTGIS/ENO1/EIF4EBP1/E2F1/CYBB/NOL3/PMAIP1/MTOR/LMNA/CCNB1/SRC/HMOX1/LIMD1/PSMD8/CFLAR/USP19/UBB/PSMD1/PSMD2/RBPJ/ATF4/SLC2A4/PSMF1/RPS27A/FOXO1/CASR/KCNMB1/FAS/PICK1/PINK1/NAMPT/NDRG1/ATP6V1A/UBA52/PSMD9/IRAK1/PSMA5/VASN/MDM4/PSMB7/HIF3A/PRKCE/AK4/EPAS1/PSMD5/CITED2/PSME2/ATP6V1G1/SFRP1/SIRT2/PSMB5/CD34/ZFP36L1/CPEB1/PSMB4/MALAT1/PSMA3/HIF1AN/BACH1/PPARD/CLCA1/PSMD10/ATG7/PSMB1/PSMD7/PSMB3/CCDC115/KCNK2/PSMC5/BAD/MGARP/PSMD11/SIRT1	82
BP	GO:0010822	positive regulation of mitochondrion organization	46/4749	117/18670	0.0006498	0.01173	0.009539	PPIF/TP73/PLAUR/MLLT11/YWHAH/MMP9/YWHAE/TP63/YWHAZ/E2F1/HK2/BAX/PMAIP1/USP36/SAE1/MOAP1/SFN/BMF/BAP1/HTT/HIP1R/PDCD5/BIK/NMT1/HPS4/SMURF1/BID/PINK1/TFDP2/BAK1/GBA/YWHAQ/PARK7/RAC2/ZNF205/GSK3A/RHOU/UBL5/CIDEB/TNFSF10/HSPA1L/VPS13D/FZD5/SREBF2/BAD/MGARP	46
BP	GO:0042035	regulation of cytokine biosynthetic process	45/4749	114/18670	0.0006689	0.01204	0.009792	EGR1/EBI3/IL1B/CD86/CD276/IL21/IL10/KLF4/CD80/IRF4/BCL3/TLR8/TIRAP/CLEC7A/TNF/ZFP36/TNFRSF8/CYBB/TLR4/FOXP3/CARD9/STAT3/CCR2/HMOX1/MAP2K3/CD74/PTPRC/SIGIRR/MAST2/LAG3/TLR6/CEBPB/CD3E/CARD11/GHRL/IL4/MAPKAPK2/TYROBP/TRAF6/ASB1/GLMN/ZFPM1/GATA3/PTAFR/CX3CR1	45
BP	GO:0015931	nucleobase-containing compound transport	84/4749	241/18670	0.0006712	0.01204	0.009798	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	84
BP	GO:0002705	positive regulation of leukocyte mediated immunity	51/4749	133/18670	0.0006789	0.01212	0.009857	IL1B/CD1E/IL18/IL21/NLRP3/IL1R1/TNFSF4/TFRC/ULBP2/TNF/CD1A/FOXP3/GAB2/RAET1E/CD1C/IL4R/RSAD2/HLA-H/HLA-G/TP53BP1/SH2D1A/BTK/CD1B/CD177/CD1D/PTPRC/HLA-E/MICA/NOD2/IL12RB1/ARG1/LAG3/CADM1/LTA/IL18R1/IL13/TRAF2/LAMP1/TNFSF13/IL4/ULBP1/MAD2L2/TRAF6/SPHK2/FZD5/TGFB1/KLRK1/GATA3/PTAFR/P2RX7/IL23A	51
BP	GO:0009142	nucleoside triphosphate biosynthetic process	68/4749	188/18670	0.0006801	0.01212	0.009857	TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/TYMS/GPI/CBFA2T3/SIRT6/HK2/NUP98/ENTPD5/CMPK2/DNAJC30/STAT3/DTYMK/PGM2L1/PKM/AK5/ALDOC/VCP/OGDH/HTR2A/PFKFB4/NUP153/NME4/PINK1/DDIT4/VPS9D1/GALK1/PFKFB2/NUP88/ENO3/PRKAG2/NME3/POM121C/AK4/NUP205/RAE1/NUP50/IMPDH1/ALDOA/IL4/AK1/CMPK1/CTPS2/UCK2/INSR/NUPR1/SPHK2/NUP93/PFKL/ALDOB/NUP35/NME9/AAAS/TAZ/TGFB1/NUP62/P2RX7/SEH1L/NCOR1/NME2	68
BP	GO:0030071	regulation of mitotic metaphase/anaphase transition	24/4749	51/18670	0.0006809	0.01212	0.009857	ESPL1/CENPF/AURKB/BUB1B/TTK/CDT1/TRIP13/CDC20/DLGAP5/BUB1/CDC6/PLK1/CCNB1/CENPE/FBXO5/NDC80/ANAPC11/USP44/XRCC3/MAD2L2/KLHL22/APC/ATM/DUSP1	24
BP	GO:0009124	nucleoside monophosphate biosynthetic process	74/4749	208/18670	0.0007038	0.01249	0.01016	TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/TYMS/GPI/CBFA2T3/SIRT6/DHODH/HK2/TK1/NUP98/ENTPD5/DNAJC30/STAT3/PFAS/PGM2L1/PKM/AK5/ALDOC/VCP/OGDH/HTR2A/PFKFB4/HPRT1/NUP153/AK3/LHPP/PINK1/UPRT/DDIT4/DCTD/VPS9D1/GALK1/PFKFB2/NUP88/ENO3/AMPD2/PRKAG2/POM121C/AK4/NUP205/RAE1/NUP50/APRT/IMPDH1/ALDOA/AMPD3/IL4/AK1/CMPK1/UCK2/INSR/NUPR1/SPHK2/PRPS1/NUP93/PFKL/ALDOB/NUP35/AAAS/TAZ/AK2/TGFB1/NUP62/P2RX7/SEH1L/NCOR1	74
BP	GO:0050708	regulation of protein secretion	151/4749	472/18670	0.0007151	0.01263	0.01028	TWIST1/IL1B/MAPK11/NLRP3/ADORA2A/CSF1R/IL10/ABCG1/RAC1/TLR8/IL17A/GAPDH/HK1/PIM3/RAB11FIP1/SLC16A1/TNFSF4/LGALS9/PML/GPI/MYH10/HMGB1/TNF/TNFRSF4/CD200/BLK/TLR4/BTN2A2/LILRA2/TNFRSF21/FOXP3/ADTRP/MMP12/IL1R2/IL4R/RSAD2/FFAR2/FRMD4A/FCN1/SRC/TIAM1/ABAT/SYT4/PAM/ARRB1/CCL3/ATP13A2/PTGER4/ENY2/HAVCR2/C2CD2L/SRI/CD33/TGFB3/ENHO/PER2/CASR/TCF7L2/SPTBN1/EZR/PRKCA/TRPM4/NADK/HLA-E/AIF1/ANXA5/OXCT1/TLR2/KCNN4/PFKFB2/CD58/NOD2/PSMD9/LRP1/IL27RA/IL26/OSM/CADM1/CACNA2D2/SIRT3/CNR1/C1QTNF3/TLR6/RHBDD3/TFAP2B/RAB11FIP3/ACVR1C/SLC25A5/IL17RC/ANXA4/DEFB114/SYT11/PRKCE/SIDT2/LRP5L/ARNTL/SRGN/IRF3/GLUD1/ZC3H12A/PAEP/RABGEF1/LILRA5/BRSK2/IL13/KRT20/SFRP1/TRAF2/CD2AP/PIK3C3/IFNGR1/GHRL/KCNG2/CPT1A/CD34/ARL2BP/RIPK2/TNFRSF1B/MYOM1/RAB11FIP5/F2R/SERP1/DOC2B/CLEC5A/TRAF6/ARF6/HDAC9/SLC25A4/CARD8/PARD6A/PFKL/ARL2/FZD5/NPFF/PPARD/SLC9B2/FFAR1/TGFB1/GLMN/ADAM9/NDUFAF2/TRIM16/GATA3/PDX1/P2RX7/GIPR/LRRC32/SYBU/VEGFC/BAD/GJA5	151
BP	GO:1905819	negative regulation of chromosome separation	20/4749	40/18670	0.0007177	0.01263	0.01028	CENPF/AURKB/BUB1B/TTK/CDT1/TRIP13/CDC20/PTTG1/BUB1/PLK1/CCNB1/FBXO5/NDC80/USP44/XRCC3/MAD2L2/KLHL22/APC/ATM/DUSP1	20
BP	GO:0009167	purine ribonucleoside monophosphate metabolic process	113/4749	340/18670	0.0007179	0.01263	0.01028	PPIF/CDK1/TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/COX8A/GPI/CBFA2T3/SIRT6/HK2/HSPA1A/NUP98/CTNS/TJP2/SLC25A23/ENTPD5/ABCD1/DNAJC30/STAT3/TSPO/FXN/CCNB1/PFAS/PGM2L1/PKM/AK5/ALDOC/VCP/OGDH/HTR2A/NDUFB11/COX6A1/PFKFB4/HPRT1/UQCRC1/SLC25A25/NUP153/FAM20C/AK3/NDUFB8/LHPP/ATP1B1/BID/PINK1/DDIT4/NADK/ATP6V1A/VPS9D1/FIGNL1/GALK1/PFKFB2/NDUFS1/NUP88/ENO3/AMPD2/PRKAG2/NDUFS7/MYH7/PARK7/POM121C/NDUFB10/AK4/MYH4/NUP205/RAE1/NUP50/NDUFC1/APRT/IMPDH1/NDUFA9/NUDT3/COX4I1/LRGUK/UQCR11/CARD11/ALDOA/GUK1/AMPD3/IL4/ISCU/NDUFA12/NT5E/AK1/INSR/NUPR1/SPHK2/NUP93/PFKL/ALDOB/NUP35/AAAS/OLA1/TAZ/AK2/NDUFA4/MYH6/NDUFB2/TGFB1/NT5C2/NDUFA13/NMNAT1/NUP62/P2RX7/SEH1L/NCOR1/BAD	113
BP	GO:0072524	pyridine-containing compound metabolic process	70/4749	195/18670	0.0007287	0.01273	0.01035	TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/PTGIS/ENO1/PGAM1/PFKP/GPI/CBFA2T3/SIRT6/HK2/NUP98/ENTPD5/TP53I3/STAT3/PGM2L1/PKM/ALDOC/VCP/OGDH/HTR2A/PDXP/PDHB/PFKFB4/NUP153/PDHX/PNP/MDH2/NAMPT/DDIT4/NADK/GALK1/PARP16/PFKFB2/NUP88/ENO3/SHPK/PRKAG2/POM121C/NUP205/RAE1/NUDT17/IDO1/NUP50/ALDOA/NT5E/FMO2/RNLS/NNT/RPE/INSR/NUPR1/NUP93/PFKL/ALDOB/NUP35/PGD/AAAS/MPC1/NMNAT1/NMNAT3/NUP62/P2RX7/SEH1L/NCOR1/ASPDH	70
BP	GO:0043620	regulation of DNA-templated transcription in response to stress	49/4749	127/18670	0.0007288	0.01273	0.01035	EGR1/VEGFA/NOTCH1/KLF2/ATF3/HSPA5/HSPA1A/HMOX1/LIMD1/PSMD8/UBB/PSMD1/PSMD2/RBPJ/ATF4/PSMF1/RPS27A/HSF2/UBA52/MUC1/HSF4/PSMD9/PSMA5/DDIT3/JUN/PSMB7/CHEK1/HIF3A/EPAS1/PSMD5/CITED2/CEBPB/RBL2/BAG3/PSME2/SIRT2/PSMB5/PSMB4/MBTPS2/PSMA3/HIF1AN/BACH1/PSMD10/PSMB1/PSMD7/PSMB3/PSMC5/SESN2/PSMD11	49
BP	GO:0097501	stress response to metal ion	11/4749	17/18670	0.000729	0.01273	0.01035	HSPA5/MT1E/MT2A/MT1X/MT1H/MT1G/PARK7/MT1A/MT1B/MT1M/MT1F	11
BP	GO:0008608	attachment of spindle microtubules to kinetochore	17/4749	32/18670	0.0007363	0.01275	0.01037	AURKB/KIF2C/CDT1/NEK2/SPAG5/RACGAP1/NUF2/CCNB1/CENPE/NDC80/BOD1/ECT2/SIRT2/APC/CHAMP1/CDC42/SEH1L	17
BP	GO:0045589	regulation of regulatory T cell differentiation	17/4749	32/18670	0.0007363	0.01275	0.01037	DUSP10/BCL6/TNFRSF18/CBFB/TNFSF4/LGALS9/IL2RA/BTN2A2/FOXP3/CTLA4/HLA-G/LILRB4/KAT2A/LILRB2/LAG3/CD46/TGFB1	17
BP	GO:0071353	cellular response to interleukin-4	17/4749	32/18670	0.0007363	0.01275	0.01037	MRC1/RPL3/TUBA1B/PML/HSPA5/IL4R/PARP14/MCM2/IL2RG/CD300LF/CORO1A/ADAMTS13/ARG1/SHPK/FASN/JAK3/GATA3	17
BP	GO:0048525	negative regulation of viral process	40/4749	99/18670	0.0007578	0.01309	0.01065	IFIT1/ISG15/APOBEC3H/PML/MX1/TNF/ZFP36/GSN/TRIM25/TRIM26/IFIT5/RSAD2/FCN1/IFITM2/TRIM62/CCL3/BST2/MORC2/OASL/ISG20/TRIM13/BANF1/IFITM3/AICDA/IFITM1/MID2/JUN/CCNK/ZNF639/ZC3H12A/OAS1/IFI16/ILF3/ZC3HAV1/TRIM35/STAT1/SETDB1/CHMP3/TRIM15/TRIM5	40
BP	GO:0009123	nucleoside monophosphate metabolic process	123/4749	375/18670	0.0007619	0.01312	0.01067	PPIF/CDK1/TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/TYMS/COX8A/GPI/CBFA2T3/SIRT6/DHODH/HK2/TK1/HSPA1A/NUP98/CTNS/TJP2/SLC25A23/ENTPD5/CMPK2/ABCD1/DNAJC30/STAT3/TSPO/FXN/CCNB1/DTYMK/PFAS/PGM2L1/PKM/AK5/ALDOC/VCP/OGDH/HTR2A/NDUFB11/COX6A1/PFKFB4/HPRT1/UQCRC1/SLC25A25/NUP153/FAM20C/AK3/NDUFB8/LHPP/ATP1B1/BID/PINK1/UPRT/DDIT4/NADK/ATP6V1A/DCTD/VPS9D1/FIGNL1/GALK1/PFKFB2/NDUFS1/NUP88/ENO3/AMPD2/PRKAG2/NDUFS7/MYH7/PARK7/POM121C/NDUFB10/AK4/MYH4/NUP205/RAE1/NUP50/NDUFC1/APRT/IMPDH1/NDUFA9/NUDT3/COX4I1/LRGUK/UQCR11/CARD11/ALDOA/GUK1/AMPD3/IL4/ISCU/NDUFA12/NT5E/AK1/CMPK1/UCK2/INSR/NUPR1/SPHK2/PRPS1/NUP93/PFKL/ALDOB/NUP35/AAAS/OLA1/TAZ/AK2/NDUFA4/MYH6/NDUFB2/TGFB1/NT5C2/NDUFA13/NMNAT1/NUP62/P2RX7/SEH1L/NCOR1/BAD	123
BP	GO:1902110	positive regulation of mitochondrial membrane permeability involved in apoptotic process	27/4749	60/18670	0.0007755	0.01329	0.01081	TP73/BNIP3L/YWHAH/YWHAE/TP63/YWHAZ/E2F1/HSPA1A/BAX/PMAIP1/MOAP1/SFN/BMF/HIP1R/EYA2/NMT1/BID/TFDP2/BAK1/YWHAQ/SLC25A5/STPG1/ZNF205/GSK3A/RHOT2/FZD9/BAD	27
BP	GO:0050852	T cell receptor signaling pathway	72/4749	202/18670	0.0007761	0.01329	0.01081	CD276/WNK1/PTPN6/LGALS3/CEACAM1/HLA-DQB2/BTN2A2/SPPL3/TNFRSF21/FOXP3/ERMAP/CTLA4/PSMD8/LILRB4/PDE4D/BTK/PDE4B/PSMD1/PSMD2/PAK1/GRAP2/UBE2N/RPS3/PSMF1/EIF2B3/PAK3/HLA-DPA1/PTPRC/EZR/CYLD/RFTN1/DUSP22/LAT/HLA-DRA/KCNN4/PSMD9/TXK/PSMA5/THY1/PSMB7/FBXW11/PSMD5/ZC3H12A/ITK/CD3E/HLA-DQA2/PSME2/BTRC/CARD11/PSMB5/BTN3A2/PRNP/RIPK2/PSMB4/HLA-DPB1/TRAF6/PSMA3/THEMIS/PSMD10/PSMB1/WAS/PSMD7/PSMB3/HHLA2/MAPK1/HLA-DRB1/ZAP70/PSMC5/GATA3/FYN/PAK2/PSMD11	72
BP	GO:0048771	tissue remodeling	65/4749	179/18670	0.0007825	0.01337	0.01087	VDR/NCDN/LIF/IL18/IL21/CSF1R/ACP5/RASSF2/RAC1/TFRC/GPNMB/CEACAM1/SPP1/HMGB1/LRRK1/NOL3/BAX/TPP1/CAPN1/CCR2/SRC/PPARGC1B/MERTK/TGM2/CTHRC1/CST3/AXL/TGFB3/RAB3D/RBPJ/S1PR1/JAG1/PRKCA/BAK1/ARG1/PLEKHM1/ACVR2B/TIMP1/CA2/RAC2/EPAS1/LRP5L/TPH1/IL7/FLT4/BGLAP/SFRP1/RSPO3/TNFRSF11B/SUCO/F2R/LRP6/TRAF6/FGF8/BCR/LIPA/TMEM119/TNFSF11/ZNF675/THBS4/TGFB1/TMEM64/P2RX7/IL23A/GJA5	65
BP	GO:0021762	substantia nigra development	21/4749	43/18670	0.000792	0.01349	0.01098	TTBK1/YWHAH/YWHAE/SYNGR3/HSPA5/CNP/SEC16A/MAPKAP1/FGF9/NDRG2/YWHAQ/BASP1/CKB/GNB4/INA/GLUD1/PADI2/SIRT2/ZNF148/CDC42/ACTB	21
BP	GO:0046686	response to cadmium ion	28/4749	63/18670	0.0007958	0.01352	0.011	CDK1/MMP9/GSN/CYBB/MT1E/MT2A/DTYMK/NUDT1/HMOX1/MT1X/MT1H/ARG1/SUMO1/MT1G/JUN/PPP5C/PRNP/MT1A/GCLC/MT1B/MT1M/NCF1/FOS/GSS/OGG1/MAPK1/ERCC1/MT1F	28
BP	GO:0019362	pyridine nucleotide metabolic process	68/4749	189/18670	0.0008019	0.01355	0.01102	TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/PTGIS/ENO1/PGAM1/PFKP/GPI/CBFA2T3/SIRT6/HK2/NUP98/ENTPD5/TP53I3/STAT3/PGM2L1/PKM/ALDOC/VCP/OGDH/HTR2A/PDHB/PFKFB4/NUP153/PDHX/MDH2/NAMPT/DDIT4/NADK/GALK1/PARP16/PFKFB2/NUP88/ENO3/SHPK/PRKAG2/POM121C/NUP205/RAE1/NUDT17/IDO1/NUP50/ALDOA/NT5E/FMO2/RNLS/NNT/RPE/INSR/NUPR1/NUP93/PFKL/ALDOB/NUP35/PGD/AAAS/MPC1/NMNAT1/NMNAT3/NUP62/P2RX7/SEH1L/NCOR1/ASPDH	68
BP	GO:0046496	nicotinamide nucleotide metabolic process	68/4749	189/18670	0.0008019	0.01355	0.01102	TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/PTGIS/ENO1/PGAM1/PFKP/GPI/CBFA2T3/SIRT6/HK2/NUP98/ENTPD5/TP53I3/STAT3/PGM2L1/PKM/ALDOC/VCP/OGDH/HTR2A/PDHB/PFKFB4/NUP153/PDHX/MDH2/NAMPT/DDIT4/NADK/GALK1/PARP16/PFKFB2/NUP88/ENO3/SHPK/PRKAG2/POM121C/NUP205/RAE1/NUDT17/IDO1/NUP50/ALDOA/NT5E/FMO2/RNLS/NNT/RPE/INSR/NUPR1/NUP93/PFKL/ALDOB/NUP35/PGD/AAAS/MPC1/NMNAT1/NMNAT3/NUP62/P2RX7/SEH1L/NCOR1/ASPDH	68
BP	GO:0009126	purine nucleoside monophosphate metabolic process	113/4749	341/18670	0.0008088	0.01355	0.01102	PPIF/CDK1/TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/COX8A/GPI/CBFA2T3/SIRT6/HK2/HSPA1A/NUP98/CTNS/TJP2/SLC25A23/ENTPD5/ABCD1/DNAJC30/STAT3/TSPO/FXN/CCNB1/PFAS/PGM2L1/PKM/AK5/ALDOC/VCP/OGDH/HTR2A/NDUFB11/COX6A1/PFKFB4/HPRT1/UQCRC1/SLC25A25/NUP153/FAM20C/AK3/NDUFB8/LHPP/ATP1B1/BID/PINK1/DDIT4/NADK/ATP6V1A/VPS9D1/FIGNL1/GALK1/PFKFB2/NDUFS1/NUP88/ENO3/AMPD2/PRKAG2/NDUFS7/MYH7/PARK7/POM121C/NDUFB10/AK4/MYH4/NUP205/RAE1/NUP50/NDUFC1/APRT/IMPDH1/NDUFA9/NUDT3/COX4I1/LRGUK/UQCR11/CARD11/ALDOA/GUK1/AMPD3/IL4/ISCU/NDUFA12/NT5E/AK1/INSR/NUPR1/SPHK2/NUP93/PFKL/ALDOB/NUP35/AAAS/OLA1/TAZ/AK2/NDUFA4/MYH6/NDUFB2/TGFB1/NT5C2/NDUFA13/NMNAT1/NUP62/P2RX7/SEH1L/NCOR1/BAD	113
BP	GO:1905710	positive regulation of membrane permeability	29/4749	66/18670	0.0008111	0.01355	0.01102	PPIF/TP73/BNIP3L/YWHAH/YWHAE/TP63/YWHAZ/E2F1/HSPA1A/BAX/PMAIP1/MOAP1/SFN/BMF/HIP1R/EYA2/NMT1/BID/TFDP2/BAK1/YWHAQ/SLC25A5/STPG1/ZNF205/GSK3A/RHOT2/FZD9/SPG7/BAD	29
BP	GO:0002825	regulation of T-helper 1 type immune response	15/4749	27/18670	0.0008142	0.01355	0.01102	IL1B/IL18/IL1R1/CD80/TNFSF4/IL4R/CCR2/HAVCR2/HLX/IL12RB1/IL27RA/IL18R1/RIPK2/JAK3/IL23A	15
BP	GO:0006735	NADH regeneration	15/4749	27/18670	0.0008142	0.01355	0.01102	TPI1/GAPDH/HK1/ENO1/PGAM1/PFKP/GPI/HK2/PGM2L1/PKM/ALDOC/ENO3/ALDOA/PFKL/ALDOB	15
BP	GO:0061621	canonical glycolysis	15/4749	27/18670	0.0008142	0.01355	0.01102	TPI1/GAPDH/HK1/ENO1/PGAM1/PFKP/GPI/HK2/PGM2L1/PKM/ALDOC/ENO3/ALDOA/PFKL/ALDOB	15
BP	GO:0061718	glucose catabolic process to pyruvate	15/4749	27/18670	0.0008142	0.01355	0.01102	TPI1/GAPDH/HK1/ENO1/PGAM1/PFKP/GPI/HK2/PGM2L1/PKM/ALDOC/ENO3/ALDOA/PFKL/ALDOB	15
BP	GO:0016331	morphogenesis of embryonic epithelium	56/4749	150/18670	0.0008207	0.01362	0.01108	TWIST1/SDC4/JAG2/STIL/MTHFD1L/LUZP1/KIF20B/PLXNB2/TGFB1I1/TP63/PTCH1/ST14/SEMA4C/SKI/ALX1/CTHRC1/DVL3/FZD6/PTK7/KAT2A/LMO4/ARHGAP35/SPINT1/STK3/LIAS/SALL4/VASP/IFT122/CFL1/TCTN1/DVL1/MTHFD1/SCRIB/IFT172/RALA/SOX8/GDF7/ARID1A/EPB41L5/SOX11/SHROOM3/SFRP1/ADM/LRP6/PRKACB/TRAF6/FGF8/MED12/TGFB1/GLMN/RARA/RDH10/LAMA5/GATA3/PDX1/VEGFC	56
BP	GO:0007584	response to nutrient	77/4749	219/18670	0.0008243	0.01365	0.0111	VDR/IL1B/PPARG/ITGA2/KANK2/CDKN2B/FES/SRF/BCL11A/LDHA/SLC16A1/SPP1/TYMS/ASCL1/DHODH/GSN/CYBB/CXCL10/TRIM25/MTOR/GDAP1/TSPO/PIM1/HMOX1/P2RX1/PKM/P2RY11/AMIGO1/PDXP/P2RX6/USF2/HMGCL/NMRAL1/PHEX/ACSL1/NQO1/CASR/TRPM4/ADIPOR2/OXCT1/ABCA1/NOD2/ARG1/LTA/GNAI2/CNR1/CYP27B1/CYBA/TBXA2R/CD3E/ACSL4/COX4I1/BGLAP/SFRP1/ALDH3A1/ADIPOQ/TNFRSF11B/P2RX5/POR/SLC27A4/GCLC/NNT/P2RY1/STAT1/OGG1/PPARD/TGFB1/MGMT/RARA/CCND1/SETDB1/AMELX/PDX1/P2RX7/GIPR/ERCC1/FYN	77
BP	GO:1903747	regulation of establishment of protein localization to mitochondrion	31/4749	72/18670	0.0008281	0.01365	0.0111	TP73/BNIP3L/YWHAH/DNAJA1/YWHAE/TP63/YWHAZ/E2F1/PMAIP1/BAG4/USP36/SAE1/SFN/BAP1/PDCD5/PARL/NMT1/HPS4/BID/PINK1/TFDP2/YWHAQ/RAC2/BAG3/GSK3A/RHOU/UBL5/HSPA1L/FZD5/SREBF2/BAD	31
BP	GO:0007006	mitochondrial membrane organization	51/4749	134/18670	0.0008288	0.01365	0.0111	PPIF/TP73/BNIP3L/YWHAH/YWHAE/TP63/YWHAZ/E2F1/HK2/HSPA1A/NOL3/BAX/PMAIP1/NAIF1/CNP/STAT3/MOAP1/SFN/BMF/TIMM10/CAMK2A/HIP1R/PDCD5/TMEM11/COX18/EYA2/NMT1/BID/PINK1/TIMM22/TIMM50/ROMO1/TFDP2/BAK1/CHCHD6/YWHAQ/SLC25A5/STPG1/ZNF205/BCL2L1/GSK3A/RHOT2/FZD9/TOMM22/AGK/TAZ/NDUFA13/OMA1/SPG7/TIMM9/BAD	51
BP	GO:0045943	positive regulation of transcription by RNA polymerase I	13/4749	22/18670	0.0008312	0.01365	0.01111	UBTF/MTOR/SMARCB1/ATF4/SMARCA4/NCL/DHX33/RASL11A/ERBB2/DDX11/EIF2AK3/IPPK/PHF8	13
BP	GO:0019359	nicotinamide nucleotide biosynthetic process	55/4749	147/18670	0.0008557	0.01392	0.01132	TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/PTGIS/ENO1/PGAM1/PFKP/GPI/CBFA2T3/SIRT6/HK2/NUP98/ENTPD5/STAT3/PGM2L1/PKM/ALDOC/OGDH/HTR2A/PFKFB4/NUP153/NAMPT/DDIT4/NADK/GALK1/PARP16/PFKFB2/NUP88/ENO3/PRKAG2/POM121C/NUP205/RAE1/IDO1/NUP50/ALDOA/RNLS/INSR/NUPR1/NUP93/PFKL/ALDOB/NUP35/AAAS/NMNAT1/NMNAT3/NUP62/P2RX7/SEH1L/NCOR1/ASPDH	55
BP	GO:0019363	pyridine nucleotide biosynthetic process	55/4749	147/18670	0.0008557	0.01392	0.01132	TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/PTGIS/ENO1/PGAM1/PFKP/GPI/CBFA2T3/SIRT6/HK2/NUP98/ENTPD5/STAT3/PGM2L1/PKM/ALDOC/OGDH/HTR2A/PFKFB4/NUP153/NAMPT/DDIT4/NADK/GALK1/PARP16/PFKFB2/NUP88/ENO3/PRKAG2/POM121C/NUP205/RAE1/IDO1/NUP50/ALDOA/RNLS/INSR/NUPR1/NUP93/PFKL/ALDOB/NUP35/AAAS/NMNAT1/NMNAT3/NUP62/P2RX7/SEH1L/NCOR1/ASPDH	55
BP	GO:0031109	microtubule polymerization or depolymerization	44/4749	112/18670	0.0008574	0.01392	0.01132	KIF2C/SKA1/FES/KIF24/RAC1/SKA3/KIF18A/HSPA1A/CENPJ/CKAP2/RANGRF/PSRC1/TPPP3/TPPP/MAPRE2/FBXO5/NUMA1/ARHGEF2/CLIP3/PAK1/RPS3/STMN3/TERF1/TUBGCP2/FGF13/STMN1/CLASP2/TUBG2/MID1/TUBB4A/MAP1S/CEP192/TRIM54/TUBG1/MAP1A/APC/ARL2/SLAIN2/TUBGCP5/NCKAP5/CDH5/KIF19/CKAP5/TUBGCP3	44
BP	GO:0050868	negative regulation of T cell activation	44/4749	112/18670	0.0008574	0.01392	0.01132	CD86/SDC4/ADORA2A/IL10/CD80/PTPN6/BCL6/CBFB/TNFSF4/LGALS3/GPNMB/CEACAM1/LGALS9/HMGB1/IL2RA/BTN2A2/TNFRSF21/FOXP3/CTLA4/IL4R/SMAD7/HLA-G/TIGIT/HAVCR2/CD74/CLEC4G/HLX/DUSP22/LILRB2/ARG1/LAG3/ERBB2/CEBPB/IDO1/DTX1/PDCD1LG2/ZC3H12A/NRARP/DLG5/PRNP/TGFB1/GLMN/JAK3/LRRC32	44
BP	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	18/4749	35/18670	0.0008584	0.01392	0.01132	TP73/YWHAH/YWHAE/TP63/YWHAZ/E2F1/BAX/PMAIP1/SFN/HIP1R/NMT1/BID/TFDP2/BAK1/YWHAQ/ZNF205/GSK3A/BAD	18
BP	GO:0009127	purine nucleoside monophosphate biosynthetic process	66/4749	183/18670	0.000882	0.0142	0.01155	TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/GPI/CBFA2T3/SIRT6/HK2/NUP98/ENTPD5/DNAJC30/STAT3/PFAS/PGM2L1/PKM/AK5/ALDOC/VCP/OGDH/HTR2A/PFKFB4/HPRT1/NUP153/AK3/LHPP/PINK1/DDIT4/VPS9D1/GALK1/PFKFB2/NUP88/ENO3/AMPD2/PRKAG2/POM121C/AK4/NUP205/RAE1/NUP50/APRT/IMPDH1/ALDOA/AMPD3/IL4/AK1/INSR/NUPR1/SPHK2/NUP93/PFKL/ALDOB/NUP35/AAAS/TAZ/AK2/TGFB1/NUP62/P2RX7/SEH1L/NCOR1	66
BP	GO:0009168	purine ribonucleoside monophosphate biosynthetic process	66/4749	183/18670	0.000882	0.0142	0.01155	TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/GPI/CBFA2T3/SIRT6/HK2/NUP98/ENTPD5/DNAJC30/STAT3/PFAS/PGM2L1/PKM/AK5/ALDOC/VCP/OGDH/HTR2A/PFKFB4/HPRT1/NUP153/AK3/LHPP/PINK1/DDIT4/VPS9D1/GALK1/PFKFB2/NUP88/ENO3/AMPD2/PRKAG2/POM121C/AK4/NUP205/RAE1/NUP50/APRT/IMPDH1/ALDOA/AMPD3/IL4/AK1/INSR/NUPR1/SPHK2/NUP93/PFKL/ALDOB/NUP35/AAAS/TAZ/AK2/TGFB1/NUP62/P2RX7/SEH1L/NCOR1	66
BP	GO:0038061	NIK/NF-kappaB signaling	66/4749	183/18670	0.000882	0.0142	0.01155	IL1B/IL18/RELB/NLRP3/NR3C2/RASSF2/BCL3/TIRAP/LGALS9/HMGB1/NFKB2/TNF/TLR4/NOL3/PDCD4/RIPK3/PSMD8/TRIP6/HAVCR2/PSMD1/PSMD2/LIMS1/RPS3/PSMF1/TNFRSF10B/CYLD/ACTN4/TLR2/TRIM44/LITAF/NOD2/TRAF4/PSMD9/IRAK1/ADIPOR1/PSMA5/IL18R1/C1QTNF3/TLR6/PSMB7/FBXW11/NFKBIA/PSMD5/NLRC3/ZC3H12A/BIRC3/PSME2/BTRC/TRAF2/PSMB5/DICER1/PSMB4/TRAF6/PSMA3/TSPAN6/EDAR/PSMD10/PSMB1/PSMD7/PSMB3/PSMC5/PRDX1/PTP4A3/ILK/PSMD11/IL23A	66
BP	GO:0018212	peptidyl-tyrosine modification	120/4749	366/18670	0.000891	0.01431	0.01164	LIF/HBEGF/VEGFA/IL18/TTK/CSF2/TYRO3/IL21/ICAM1/MVP/NTRK2/NEDD9/CSF1R/FES/NTRK1/MELK/PDGFA/HCK/CD80/TTBK1/PTPN6/EPHB1/TNFRSF18/DYRK3/CNTF/SLA/NF2/PPP2R1A/TNF/LRP8/LRRK1/BLK/PTPN1/MTOR/STAT3/PARP14/FCGR1A/SRC/EPHB4/SOCS3/FGFR1OP/MERTK/MAP2K3/ARHGEF2/SAMSN1/BTK/HTR2A/IL12RB2/NTRK3/AXL/IGF1R/CD74/UNC119/MAP2K6/DOCK3/FLT3/STK16/PTK6/CCK/PDCL3/LRP4/PTPRC/SH3BP5L/DYRK4/DUSP22/VTN/PPP2CA/TXK/THY1/OSM/FLT1/TTL/INSRR/GGNBP2/ERBB2/CD44/PIBF1/PRKCE/DDR1/NEK1/IL7/LILRA5/ITK/MAP2K4/LACRT/CD3E/FLT4/CNOT7/IL13/IL20/SFRP1/GHRL/ADIPOQ/IL4/CLK3/ARL2BP/PRNP/LTK/RIPK2/FER/SEMA4D/INSR/FGF8/TIE1/NCF1/NTF3/THBS4/TGFB1/CLK2/JAK3/ADNP/PDGFB/ZAP70/SHC1/EHD4/FYN/DLG4/PAK2/JAK1/IL23A	120
BP	GO:0002704	negative regulation of leukocyte mediated immunity	23/4749	49/18670	0.0009144	0.01458	0.01186	PTPN6/BCL6/CEACAM1/LGALS9/FOXP3/SMAD7/CCR2/HMOX1/HLA-G/BST2/HAVCR2/CLEC4G/PTPRC/HLA-E/DUSP22/MICA/ARG1/CRK/IL7R/RABGEF1/BCR/JAK3/CD96	23
BP	GO:0010273	detoxification of copper ion	10/4749	15/18670	0.000917	0.01458	0.01186	MT1E/MT2A/MT1X/MT1H/MT1G/PARK7/MT1A/MT1B/MT1M/MT1F	10
BP	GO:0045410	positive regulation of interleukin-6 biosynthetic process	10/4749	15/18670	0.000917	0.01458	0.01186	IL1B/TIRAP/CLEC7A/TNF/STAT3/CD74/TLR6/TYROBP/TRAF6/PTAFR	10
BP	GO:1990169	stress response to copper ion	10/4749	15/18670	0.000917	0.01458	0.01186	MT1E/MT2A/MT1X/MT1H/MT1G/PARK7/MT1A/MT1B/MT1M/MT1F	10
BP	GO:0018108	peptidyl-tyrosine phosphorylation	119/4749	363/18670	0.0009388	0.01485	0.01208	LIF/HBEGF/VEGFA/IL18/TTK/CSF2/TYRO3/IL21/ICAM1/MVP/NTRK2/NEDD9/CSF1R/FES/NTRK1/MELK/PDGFA/HCK/CD80/TTBK1/PTPN6/EPHB1/TNFRSF18/DYRK3/CNTF/SLA/NF2/PPP2R1A/TNF/LRP8/LRRK1/BLK/PTPN1/MTOR/STAT3/PARP14/FCGR1A/SRC/EPHB4/SOCS3/FGFR1OP/MERTK/MAP2K3/ARHGEF2/SAMSN1/BTK/HTR2A/IL12RB2/NTRK3/AXL/IGF1R/CD74/UNC119/MAP2K6/DOCK3/FLT3/STK16/PTK6/CCK/PDCL3/LRP4/PTPRC/SH3BP5L/DYRK4/DUSP22/VTN/PPP2CA/TXK/THY1/OSM/FLT1/INSRR/GGNBP2/ERBB2/CD44/PIBF1/PRKCE/DDR1/NEK1/IL7/LILRA5/ITK/MAP2K4/LACRT/CD3E/FLT4/CNOT7/IL13/IL20/SFRP1/GHRL/ADIPOQ/IL4/CLK3/ARL2BP/PRNP/LTK/RIPK2/FER/SEMA4D/INSR/FGF8/TIE1/NCF1/NTF3/THBS4/TGFB1/CLK2/JAK3/ADNP/PDGFB/ZAP70/SHC1/EHD4/FYN/DLG4/PAK2/JAK1/IL23A	119
BP	GO:0072593	reactive oxygen species metabolic process	96/4749	284/18670	0.0009395	0.01485	0.01208	IL1B/FOXM1/CDKN1A/ICAM1/KLF2/IL10/ACP5/KLF4/RAC1/PTGIS/SIRPA/NCF4/CLEC7A/MPV17/TNF/HK2/NOXA1/CYBB/TLR4/DDAH2/GADD45A/CTNS/PMAIP1/MTOR/GPX1/ABCD1/STAT3/TSPO/RIPK3/IFI6/ABCD2/PRDX3/GLS2/CFLAR/CLU/CD177/PKD2/EPHX2/PRDX5/HBA2/NQO1/FOXO1/PARL/DHFR/PREX1/PINK1/DDIT4/CD47/ROMO1/AIF1/TLR2/FANCC/PRCP/GCHFR/NDUFS1/ATP2B4/SIRT3/GNAI2/RAB27A/TLR6/VDAC1/FPR2/PARK7/GBF1/SH3PXD2B/RAC2/MPO/ZNF205/CYBA/ZC3H12A/HBG1/ARF4/PRDX6/SIRT2/CD34/POR/TYROBP/HBB/NNT/INSR/SPHK2/BCR/CCS/NCF1/SPR/TGFB1/NDUFA13/KLRK1/PDGFB/NDUFAF2/SESN2/P2RX7/CX3CR1/PRDX1/KHSRP/FYN	96
BP	GO:0033209	tumor necrosis factor-mediated signaling pathway	61/4749	167/18670	0.0009412	0.01485	0.01208	TXNDC17/TNFRSF18/TNFSF4/RFFL/EDARADD/TNFRSF12A/TNF/TNFRSF4/HSPA1A/TNFRSF8/NOL3/PIAS3/BAG4/TRAIP/PSMD8/CLIP3/PSMD1/PSMD2/LIMS1/PSMF1/TNFRSF19/CYLD/TNFRSF9/ACTN4/PSMD9/PSMA5/TNFRSF13B/LTA/PSMB7/TNFSF12/NFKBIA/TRAF1/PSMD5/TNFSF9/BIRC3/PSME2/TRAF2/PIAS4/ST18/TNFSF13/ADIPOQ/TNFRSF11B/PSMB5/TNFRSF1B/PSMB4/PSMA3/STAT1/CARD8/TNFSF11/EDAR/ZNF675/PSMD10/PSMB1/PSMD7/COMMD7/PSMB3/SPATA2/PSMC5/ILK/TNFRSF25/PSMD11	61
BP	GO:0071496	cellular response to external stimulus	112/4749	339/18670	0.0009588	0.01507	0.01226	VDR/IL1B/CDKN1A/PPARG/GAS2L1/ITGA2/ICAM1/FOSL1/CD68/KANK2/CDKN2B/FES/SRF/RAC1/BCL11A/DCTPP1/TLR8/DSC2/MTMR3/ATF3/HSPA5/TNFRSF8/CYBB/TLR4/MAP1LC3A/GADD45A/PMAIP1/MTOR/GDAP1/TMEM150C/ITFG2/PIM1/DAP/NUDT1/HMOX1/P2RY11/MAP3K2/PTGER4/AMIGO1/PDXP/AXL/KCNJ2/USF2/ATF4/NMRAL1/NUAK2/ASNS/PHEX/AMBRA1/ARHGAP35/FOXO1/CASR/AQP2/FAS/PICK1/TNFRSF10B/MAP3K5/WDR24/NAMPT/PTPRC/TRPM4/C12orf66/AIF1/ITGA6/ULK1/BAK1/GBA/CASP8AP2/JUN/SLC38A2/CYP27B1/CHEK1/PIEZO1/MYBBP1A/KIAA1324/CYBA/ZC3H12A/BAG3/KLF10/MAP2K4/IL13/IFI16/KRT20/BGLAP/NPRL3/SFRP1/PIK3C3/EIF2AK3/GCLC/WDR45/CNN2/P2RY1/MAX/RRP8/PIK3R4/RALB/PPP1R9B/FOS/RRAGB/WRN/ATG7/TGFB1/ADNP/MAPK1/SESN2/P2RX7/SEH1L/SREBF2/BAD/FYN/SIRT1/NPRL2	112
BP	GO:0006998	nuclear envelope organization	24/4749	52/18670	0.0009624	0.01507	0.01226	CDK1/CCNB2/PPP2R1A/REEP3/PLK1/TMEM43/LMNA/CCNB1/REEP4/SUN2/PRKCA/LEMD3/PPP2CA/BANF1/SPAG4/EMD/TMEM170A/PARP11/NSFL1C/PRKCB/CHMP2A/NUP93/NEK9/LPIN1	24
BP	GO:0032653	regulation of interleukin-10 production	24/4749	52/18670	0.0009624	0.01507	0.01226	CD83/IRF4/BCL3/TNFSF4/CLEC7A/LGALS9/HMGB1/TLR4/TNFRSF21/FOXP3/TIGIT/CD47/TLR2/NOD2/CD46/PIBF1/IDO1/PDCD1LG2/LILRA5/CD34/TYROBP/DLL1/JAK3/IL23A	24
BP	GO:0044773	mitotic DNA damage checkpoint	39/4749	97/18670	0.0009797	0.01531	0.01245	GTSE1/E2F7/E2F8/CDK1/CDKN1A/AURKA/CLSPN/ZNF385A/PML/E2F1/PLK2/BAX/CDC25C/GADD45A/CCNB1/SFN/RPL26/CDK2/RFWD3/FBXO31/CARM1/CNOT3/TFDP2/MUC1/MDM4/TAOK3/RBL2/ZNF830/EME1/CNOT7/MDC1/GIGYF2/GML/CHEK2/ATM/CCND1/SYF2/TIPIN/RAD9A	39
BP	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	82/4749	237/18670	0.0009901	0.01535	0.01248	NDFIP2/IL1B/SQSTM1/IL1RN/SIRPA/TIRAP/TIFA/CANT1/LGALS9/UBD/TNF/PLK2/TLR4/S100A13/TRIM25/IFIT5/CARD9/HMOX1/TGM2/CFLAR/TRIM62/UBE2I/PIM2/BST2/CD74/UBE2N/CTH/LGALS1/TRIM22/TNFRSF19/TNFRSF10B/PINK1/SLC35B2/BRD4/TRIM13/SECTM1/LITAF/NOD2/FKBP1A/TANK/IRAK1/OTUD7B/TLR6/MID2/PPP5C/PRKCE/ECT2/NLRC3/MAP3K3/IRF3/ZC3H12A/BIRC3/TMED4/TNIP3/BTRC/TRAF2/CARD11/ADIPOQ/RIPK2/ESR1/F2R/TNFSF10/IL36A/PRKCB/TRAF6/SPHK2/AKAP13/GOLT1B/TSPAN6/STAT1/CARD8/TNFSF11/EDAR/SHISA5/ANKRD17/NUP62/CX3CR1/FYN/IL37/ZFAND6/SIRT1/TRIM5	82
BP	GO:0032392	DNA geometric change	46/4749	119/18670	0.0009939	0.01535	0.01248	HMGB3/TOP2A/MCM4/TREX1/ERCC6L/MCM5/RAD54L/DDB2/HMGB1/RAD51/MCM2/CDC45/PIF1/GINS2/UBB/GINS1/POLQ/GINS4/XRCC6/ZRANB3/RFC2/RPS27A/MCM7/RAD23B/HELQ/DSCC1/UBA52/ERCC8/RECQL5/CHTF8/MCM3/ERCC2/GTF2H2/RECQL4/GTF2H1/POT1/DDX11/DNA2/MNAT1/HELB/CETN2/GTF2H5/XPA/WRN/CUL4A/RAD54B	46
BP	GO:0001844	protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	16/4749	30/18670	0.0009941	0.01535	0.01248	TP73/YWHAH/YWHAE/TP63/YWHAZ/E2F1/BAX/PMAIP1/MOAP1/SFN/BMF/NMT1/BID/TFDP2/YWHAQ/BAD	16
BP	GO:0002828	regulation of type 2 immune response	16/4749	30/18670	0.0009941	0.01535	0.01248	CD86/IL18/NLRP3/BCL6/TNFSF4/IL4R/RSAD2/CCR2/CD74/HLX/NOD2/IL27RA/ARG1/IDO1/RARA/GATA3	16
BP	GO:0090200	positive regulation of release of cytochrome c from mitochondria	16/4749	30/18670	0.0009941	0.01535	0.01248	PPIF/PLAUR/MLLT11/MMP9/BAX/PMAIP1/MOAP1/BMF/PDCD5/BIK/BID/PINK1/BAK1/CIDEB/TNFSF10/BAD	16
BP	GO:0032613	interleukin-10 production	25/4749	55/18670	0.001002	0.01543	0.01255	CD83/IRF4/ISG15/BCL3/TNFSF4/CLEC7A/LGALS9/HMGB1/TLR4/TNFRSF21/FOXP3/TIGIT/CD47/TLR2/NOD2/CD46/PIBF1/IDO1/PDCD1LG2/LILRA5/CD34/TYROBP/DLL1/JAK3/IL23A	25
BP	GO:0002793	positive regulation of peptide secretion	97/4749	288/18670	0.001013	0.01557	0.01266	TWIST1/IL1B/MAPK11/NLRP3/ADORA2A/CSF1R/IL10/ABCG1/RAC1/TLR8/IL17A/GAPDH/HK1/TNFSF4/LGALS9/GPI/MYH10/HMGB1/TNF/TNFRSF4/BLK/TLR4/LILRA2/MMP12/IL4R/FFAR2/FRMD4A/FCN1/SRC/ABAT/ARRB1/CCL3/ATP13A2/PTGER4/HAVCR2/C2CD2L/SRI/CD33/TGFB3/CASR/TCF7L2/SPTBN1/EZR/TRPM4/NADK/HLA-E/AIF1/OXCT1/TLR2/KCNN4/PFKFB2/CD58/NOD2/PSMD9/LRP1/IL26/OSM/CADM1/SIRT3/ILDR1/C1QTNF3/IL17RC/PRKCE/IRF3/GLUD1/PAEP/LILRA5/IL13/CD2AP/IFNGR1/GHRL/S100A8/CD34/RIPK2/MYOM1/F2R/SERP1/DOC2B/CLEC5A/ARF6/CARD8/PARD6A/TNFSF11/FZD5/PPARD/FFAR1/TGFB1/GLMN/ADAM9/TRIM16/GATA3/PDX1/P2RX7/GIPR/SYBU/VEGFC/BAD	97
BP	GO:0032386	regulation of intracellular transport	136/4749	423/18670	0.001027	0.01574	0.0128	IL1B/GTSE1/ADORA2A/FES/KIF20B/BNIP3L/RIMS3/SPAG5/CAMK1/YIPF5/CDK5/ANXA2P2/REEP2/YWHAE/LGALS9/RBM22/SYN1/NCS1/CHRNA5/PTPN1/GAB2/ANXA2/DNAJC30/BAG4/PTPN14/MYLK2/IL4R/SORL1/USP36/SRC/SAE1/HMOX1/TENM1/GRIPAP1/SEC16A/B3GAT3/P2RX1/NUMA1/IWS1/SFN/SYT4/HTR2A/ATP2A1/ATP13A2/CAMK2A/CNIH2/PAK1/BAP1/PFN2/NUP153/SLC2A4/PDCD5/APBA2/PARL/NUCB1/STX1B/HPS4/TCF7L2/PINK1/UBE2G2/EZR/BCAP31/CRYAA/TBC1D20/DVL1/SUPT6H/INSIG1/DRD1/MYBPC3/DTNBP1/TMEM30A/NOLC1/WNT7A/CNR1/CHP1/UNC13D/PARK7/EMD/EFCAB7/FMR1/ERBB2/CABP1/OAZ2/TNNC1/RAC2/ECT2/EDEM2/SNX12/ZC3H12A/BAG3/RABGEF1/GSK3A/BRSK2/IL13/RHOU/SNAPIN/NAPB/UBL5/RAB23/LAMP1/ADIPOQ/PRNP/ARV1/FER/UHMK1/RNF139/LDLRAP1/HSPA1L/PRKCB/P2RY1/CPSF6/SPHK2/CACNB2/FBXL20/OAZ1/RBM27/FZD5/STOM/AAAS/ARHGAP1/NCBP2/ZFAND1/RUFY3/TGFB1/BCAS3/PPP1R12A/MAPK1/NUP62/UBAC2/GDI1/USP17L2/SREBF2/CHMP3/FYN/REEP1/BARD1	136
BP	GO:1903749	positive regulation of establishment of protein localization to mitochondrion	26/4749	58/18670	0.001034	0.0158	0.01285	TP73/YWHAH/YWHAE/TP63/YWHAZ/E2F1/PMAIP1/USP36/SAE1/SFN/BAP1/PDCD5/NMT1/HPS4/BID/PINK1/TFDP2/YWHAQ/RAC2/GSK3A/RHOU/UBL5/HSPA1L/FZD5/SREBF2/BAD	26
BP	GO:0002218	activation of innate immune response	106/4749	319/18670	0.001036	0.0158	0.01285	IRF7/GRAMD4/RELB/TYRO3/HCK/CLEC10A/IRF4/TLR8/HEXIM1/TIRAP/TIFA/CLEC7A/PSPC1/SFPQ/UNC93B1/HMGB1/PQBP1/HSPA1A/TLR4/LILRA2/CARD9/RSAD2/FFAR2/FCN1/SRC/SEC14L1/PSMD8/BTK/HAVCR2/UBB/PSMD1/PSMD2/PAK1/TRIL/XRCC6/UBE2N/MAP2K6/CTSB/PSMF1/IRAK3/NPLOC4/RPS27A/PAK3/PGLYRP3/LRRC14/CD300LF/CYLD/RFTN1/UBA52/TLR2/FLOT1/MUC1/NOD2/PSMD9/TANK/IRAK1/PSMA5/TLR6/MNDA/CLEC4D/PSMB7/ICAM2/FBXW11/TAB1/NFKBIA/PRKCE/PSMD5/NFKBIL1/CYBA/IRF3/BIRC3/PSME2/TNIP3/BTRC/IFI16/CARD11/PIK3C3/S100A8/PSMB5/RIPK2/ESR1/MAPKAPK2/PTPRS/COLEC12/PRKACB/PSMB4/C1QBP/TRAF6/PSMA3/PIK3R4/TSPAN6/ANKRD17/PSMD10/PSMB1/PSMD7/PSMB3/ZCCHC3/KLRK1/PSMC5/USP17L2/FYN/PAK2/PJA2/TRIM15/PSMD11/TRIM5	106
BP	GO:0016445	somatic diversification of immunoglobulins	28/4749	64/18670	0.001075	0.01636	0.01331	IL10/BATF/EXO1/BCL6/TNFSF4/TFRC/MSH6/FOXP3/PMS2P1/SWAP70/CCR6/TP53BP1/POLQ/PTPRC/SUPT6H/AICDA/IL27RA/RNF8/PMS2P5/APLF/SAMHD1/POLM/TNFSF13/IL4/MAD2L2/TGFB1/ERCC1/RNF168	28
BP	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	33/4749	79/18670	0.001082	0.01642	0.01336	FCGR1B/NCF4/IFI30/CYBB/FCGR1A/HLA-H/CD207/HLA-G/PSMD8/PSMD1/PSMD2/PSMF1/HLA-E/PSMD9/SNAP23/PSMA5/TAP1/PSMB7/VAMP3/PSMD5/CYBA/PSME2/PSMB5/LNPEP/PSMB4/PSMA3/NCF1/PSMD10/PSMB1/PSMD7/PSMB3/PSMC5/PSMD11	33
BP	GO:0051298	centrosome duplication	29/4749	67/18670	0.001086	0.01645	0.01338	CCNF/STIL/WDR62/PLK4/SAC3D1/CHMP2B/PLK2/BRCA2/CENPJ/CDK2/KAT2A/PKD2/POC1A/NUBP1/MDM1/CEP152/CHORDC1/CEP192/C10orf90/ALMS1/XRCC3/CHMP1A/TMEM67/CETN2/CHMP2A/CEP72/NUP62/CHMP3/CKAP5	29
BP	GO:0050000	chromosome localization	32/4749	76/18670	0.001089	0.01645	0.01339	CENPF/KIF2C/CDCA8/KIF14/KIFC1/CDCA5/FAM83D/GEM/CDT1/DLGAP5/SPAG5/KIF18A/CHMP2B/NUF2/NUP98/UBE2B/PSRC1/CCNB1/CENPE/NUMA1/NDC80/BOD1/TERF1/TTL/PIBF1/CHMP1A/CHMP2A/CHAMP1/ATM/TRAPPC12/NUP62/SEH1L	32
BP	GO:0032508	DNA duplex unwinding	43/4749	110/18670	0.001098	0.01651	0.01343	TOP2A/MCM4/TREX1/ERCC6L/MCM5/DDB2/RAD51/MCM2/CDC45/PIF1/GINS2/UBB/GINS1/POLQ/GINS4/XRCC6/ZRANB3/RFC2/RPS27A/MCM7/RAD23B/HELQ/DSCC1/UBA52/ERCC8/RECQL5/CHTF8/MCM3/ERCC2/GTF2H2/RECQL4/GTF2H1/POT1/DDX11/DNA2/MNAT1/HELB/CETN2/GTF2H5/XPA/WRN/CUL4A/RAD54B	43
BP	GO:0046514	ceramide catabolic process	12/4749	20/18670	0.001098	0.01651	0.01343	NAGA/NEU4/GM2A/NEU1/GBA/ACER1/ACER2/ASAH2/ASAH2B/NEU3/GALC/HEXB	12
BP	GO:0043687	post-translational protein modification	118/4749	361/18670	0.001107	0.0166	0.01351	CCNF/DTL/IGFBP4/ESCO2/SPP1/KLHL5/UBD/SOCS2/FBXL19/DDB2/CSF1/CALU/SPSB1/PROC/ASB2/F5/KLHL25/BTBD1/SOCS3/PSMD8/FBXL18/CST3/RAB13/SDC2/PSMD1/PSMD2/KLHL3/WSB2/FBXL14/IGFBP3/FAM20C/LRR1/PSMF1/KLHL9/LGALS1/NUCB1/FBXO27/FBXO31/MGAT4A/QSOX1/LRRC41/FUCA2/DSCC1/SUMF1/FN3KRP/AMTN/ERCC8/KLHL21/PSMD9/PSMA5/FBXL8/FEM1B/TTL/DCAF10/AGTPBP1/PRKCSH/PSMB7/FBXW11/TIMP1/HIF3A/EPAS1/PSMD5/KBTBD13/ASB11/CUL5/DCAF5/RABGGTB/RAB38/SPSB2/MSLN/DCAF4/UCHL3/RNF7/PSME2/DCAF17/CKAP4/BTRC/APOL1/GAN/RAB2A/FBXL4/PSMB5/FBXO11/FBXO9/NAE1/NEURL2/ASB10/PSMB4/KLHL22/PSMA3/RAB1A/FBXL22/ANKRD9/FBXL15/FBXL20/WSB1/SUMF2/FBXO44/SHISA5/COPS7A/SERPINA10/PSMD10/ATG7/ASB1/CUL4A/PSMB1/PSMD7/PSMB3/FBXO10/FEM1C/AMELX/UBE2F/PSMC5/KLHL11/FBXO4/RAB1B/KLHL13/PSMD11	118
BP	GO:0035723	interleukin-15-mediated signaling pathway	9/4749	13/18670	0.001128	0.01681	0.01367	IL2RB/STAT3/IL2RG/IL15RA/STAT5A/PLCB1/JAK3/SHC1/JAK1	9
BP	GO:0045086	positive regulation of interleukin-2 biosynthetic process	9/4749	13/18670	0.001128	0.01681	0.01367	IL1B/CD86/CD80/IRF4/CLEC7A/PTPRC/CD3E/CARD11/GLMN	9
BP	GO:0071350	cellular response to interleukin-15	9/4749	13/18670	0.001128	0.01681	0.01367	IL2RB/STAT3/IL2RG/IL15RA/STAT5A/PLCB1/JAK3/SHC1/JAK1	9
BP	GO:0050821	protein stabilization	64/4749	178/18670	0.001143	0.01699	0.01383	GTSE1/CDKN1A/RASSF2/GAPDH/TREX1/GRN/HIP1/HSPA1A/UBE2B/USP9X/ZSWIM7/WNT10B/SYVN1/MSX1/SMAD7/PIM1/USP36/SEC16A/RPL5/PIM2/CLU/USP19/DVL3/PFN2/HIP1R/CCT5/COG7/ATP1B1/HPS4/CDK7/RPL23/PINK1/MTMR9/CRYAA/STK3/DVL1/FLOT1/TAF9B/TRIM44/AAK1/MDM4/STX12/SUMO1/NAA16/CHP1/PARK7/ATP1B3/C10orf90/BAG3/CREBL2/BAG2/LAMP1/COG3/TYROBP/TESC/CHEK2/GNAQ/ZBED3/NAPG/RPL11/PER3/WIZ/A1CF/CCT3	64
BP	GO:0072522	purine-containing compound biosynthetic process	104/4749	313/18670	0.001151	0.01705	0.01387	MTHFD1L/TPI1/PDPR/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/GPI/CBFA2T3/SIRT6/HK2/SLC25A1/NUP98/ENTPD5/TECR/DNAJC30/STAT3/ADCY4/PFAS/SCD/PGM2L1/PKM/AK5/ALDOC/VCP/OGDH/HTR2A/PDHB/PPT1/PFKFB4/HPRT1/ADCY6/NUP153/ACSL1/PDHX/AK3/GUCA1C/PNP/NME4/PINK1/HSD17B8/DDIT4/SLC35B2/VPS9D1/PRPSAP2/GALK1/MTHFD1/PFKFB2/DLAT/NUP88/ENO3/AMPD2/PRKAG2/NME3/ELOVL7/MTAP/POM121C/AK4/NUP205/RAE1/ELOVL1/ADCY3/NUP50/APRT/IMPDH1/ACSL4/ALDOA/GUK1/AMPD3/IL4/PANK4/ACACB/NT5E/AK1/ACSS1/FASN/INSR/NUPR1/ADCY9/SPHK2/PRPS1/NUP93/PFKL/PAPSS2/ALDOB/NUP35/NME9/PANK1/AAAS/TAZ/AK2/TGFB1/MPC1/GSTZ1/NUP62/P2RX7/SEH1L/NCOR1/NME2	104
BP	GO:0033046	negative regulation of sister chromatid segregation	21/4749	44/18670	0.001155	0.01705	0.01387	ESPL1/CENPF/AURKB/BUB1B/TTK/CDT1/TRIP13/CDC20/PTTG1/BUB1/PLK1/CCNB1/FBXO5/NDC80/USP44/XRCC3/MAD2L2/KLHL22/APC/ATM/DUSP1	21
BP	GO:1901028	regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	21/4749	44/18670	0.001155	0.01705	0.01387	TP73/YWHAH/YWHAE/TP63/YWHAZ/E2F1/HSPA1A/BAX/PMAIP1/SFN/HIP1R/NMT1/BID/TFDP2/BAK1/YWHAQ/SLC25A5/ZNF205/GSK3A/FZD9/BAD	21
BP	GO:0032633	interleukin-4 production	17/4749	33/18670	0.001161	0.01706	0.01388	NOTCH1/CD86/NLRP3/CD83/IRF4/TNFSF4/LGALS9/FOXP3/HAVCR2/RBPJ/HLA-E/CEBPB/ITK/CD3E/RARA/ZFPM1/GATA3	17
BP	GO:0051204	protein insertion into mitochondrial membrane	17/4749	33/18670	0.001161	0.01706	0.01388	TP73/YWHAH/YWHAE/TP63/YWHAZ/E2F1/BAX/PMAIP1/MOAP1/SFN/BMF/COX18/NMT1/BID/TFDP2/YWHAQ/BAD	17
BP	GO:0010506	regulation of autophagy	108/4749	327/18670	0.001182	0.01733	0.0141	GPSM1/IL10/BNIP3L/GAPDH/ATP6V0D1/TP53INP2/CTSA/LZTS1/DAPK2/MCL1/CDK5/MTMR3/HMGB1/HK2/PLK2/CTTN/ATP6V0B/MTOR/CAPN1/TMEM150C/STAT3/TSPO/DAP/USP36/HMOX1/PIM2/BMF/ATP13A2/ATP6V1E1/HTT/TMEM150A/FYCO1/AMBRA1/ATP6V0C/PIKFYVE/TRIM22/CALCOCO2/FOXO1/SMURF1/TPCN1/PRKAB2/PINK1/WDR24/MTMR9/QSOX1/NAMPT/ATP6V1A/TRIM13/ULK1/GBA/TP53INP1/DDIT3/PRKAG2/EEF1A1/MID2/VDAC1/SLC38A9/PARK7/SH3BP4/KIAA1324/ACER2/TFEB/ZC3H12A/EEF1A2/BAG3/UVRAG/LACRT/GSK3A/IFI16/ATP6V1G1/UBQLN2/DAPK1/RAB39B/NPRL3/SIRT2/IL4/ERN1/RIPK2/LRSAM1/LAMTOR4/LAMTOR2/NUPR1/KLHL22/OSBPL7/PIP4K2A/TMEM150B/ATP6V1E2/VPS13D/IL10RA/RALB/XPA/FZD5/PIP4K2B/ATM/RRAGB/PHF23/ATG7/UCHL1/DRAM1/SESN2/MLST8/SREBF2/BAD/RAB1B/TRIB3/RAB12/SIRT1/NPRL2	108
BP	GO:0046328	regulation of JNK cascade	66/4749	185/18670	0.001219	0.01783	0.0145	IL1B/DUSP10/GADD45G/RASSF2/EPHB1/IL1RN/SIRPA/TIRAP/DNAJA1/HMGB1/TNF/FGD2/TLR4/PTPN1/GADD45A/CARD9/PDCD4/MAP3K6/ARHGEF5/TIAM1/SDCBP/MAP3K2/DVL3/IGF1R/PAK1/RPS3/FKTN/TNFRSF19/MAP3K5/PINK1/CYLD/STK3/NRK/DUSP22/NOD2/TRAF4/MAP3K11/DTNBP1/TAOK3/WNT7A/TLR6/FZD8/RAPGEF1/PHLPP1/MINK1/MAP2K4/FLT4/SFRP1/TRAF2/MAP4K1/ERN1/RIPK2/IL36A/AIDA/TRAF6/BIRC7/TNFSF11/EDAR/FZD5/NCF1/ZNF675/MAP3K9/PLCB1/NCOR1/IL37/PJA2	66
BP	GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	22/4749	47/18670	0.001229	0.01788	0.01454	CD86/IL18/NLRP3/CD83/CD80/IRF4/BCL6/CBFB/TNFSF4/LGALS9/HMGB1/FOXP3/IL4R/SMAD7/HLX/IL12RB1/ZC3H12A/RIPK2/JAK3/RARA/GATA3/IL23A	22
BP	GO:0051092	positive regulation of NF-kappaB transcription factor activity	55/4749	149/18670	0.001233	0.01788	0.01454	IL1B/IL18/NLRP3/ICAM1/NTRK1/TIRAP/LGALS9/NFKB2/TNF/HSPA1A/TLR4/TRIM25/STAT3/RIPK3/PRDX3/ARHGEF2/CFLAR/TRIM62/BTK/CLU/CAMK2A/UBB/UBE2N/RPS3/CTH/IRAK3/TRIM22/RPS27A/CARM1/PRKCI/UBA52/TLR2/TRIM13/FLOT1/NOD2/IRAK1/DHX33/IL18R1/TLR6/MID2/TAB1/TRAF1/TRIM52/TRAF2/CARD11/S100A8/RIPK2/FER/PRKCB/TRAF6/TNFSF11/TGFB1/CX3CR1/TRIM15/TRIM5	55
BP	GO:1903900	regulation of viral life cycle	55/4749	149/18670	0.001233	0.01788	0.01454	NOTCH1/TOP2A/IFIT1/ISG15/ANXA2P2/LGALS9/APOBEC3H/PML/SMC3/CHMP2B/KPNA2/MX1/TNF/GSN/TRIM25/ANXA2/TRIM26/IFIT5/RSAD2/SNF8/FCN1/IFITM2/PPIH/TRIM62/BST2/MORC2/CD74/OASL/LGALS1/ISG20/TBC1D20/TRIM13/BANF1/IFITM3/AICDA/IFITM1/MID2/FMR1/CCNK/RAD23A/ZC3H12A/OAS1/CNOT7/IFI16/ILF3/ZC3HAV1/CHMP2A/STAU1/TRIM35/STOM/NUCKS1/SETDB1/CHMP3/TRIM15/TRIM5	55
BP	GO:2001056	positive regulation of cysteine-type endopeptidase activity	55/4749	149/18670	0.001233	0.01788	0.01454	GRAMD4/PPARG/NLRP3/CASP9/TTBK1/CTSH/PERP/CLEC7A/HIP1/LGALS9/PML/HMGB1/TNF/GSN/BAX/PMAIP1/ASPH/CARD9/DAP/CYFIP2/P2RX1/ARRB1/VCP/BCL2L13/RPS3/HIP1R/PDCD5/CCK/FAS/BID/TNFRSF10B/MAP3K5/BCAP31/KHDC1/BAK1/CTSD/CASP8AP2/ACVR1C/ACER2/IFI16/DAPK1/TRAF2/EIF2AK3/S100A8/ST18/F3/CIDEB/RIPK2/F2R/TNFSF10/CARD8/NDUFA13/BAD/FYN/SIRT1	55
BP	GO:0006164	purine nucleotide biosynthetic process	100/4749	300/18670	0.001258	0.01819	0.0148	TPI1/PDPR/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/GPI/CBFA2T3/SIRT6/HK2/SLC25A1/NUP98/ENTPD5/TECR/DNAJC30/STAT3/ADCY4/PFAS/SCD/PGM2L1/PKM/AK5/ALDOC/VCP/OGDH/HTR2A/PDHB/PPT1/PFKFB4/HPRT1/ADCY6/NUP153/ACSL1/PDHX/AK3/GUCA1C/NME4/PINK1/HSD17B8/DDIT4/SLC35B2/VPS9D1/PRPSAP2/GALK1/MTHFD1/PFKFB2/DLAT/NUP88/ENO3/AMPD2/PRKAG2/NME3/ELOVL7/POM121C/AK4/NUP205/RAE1/ELOVL1/ADCY3/NUP50/APRT/IMPDH1/ACSL4/ALDOA/GUK1/AMPD3/IL4/PANK4/ACACB/AK1/ACSS1/FASN/INSR/NUPR1/ADCY9/SPHK2/PRPS1/NUP93/PFKL/PAPSS2/ALDOB/NUP35/NME9/PANK1/AAAS/TAZ/AK2/TGFB1/MPC1/GSTZ1/NUP62/P2RX7/SEH1L/NCOR1/NME2	100
BP	GO:0060337	type I interferon signaling pathway	38/4749	95/18670	0.001265	0.01821	0.01482	EGR1/IRF7/IFIT1/PTPN6/IRF4/ISG15/TREX1/OAS2/GBP2/MX1/IRF5/PTPN1/MMP12/RSAD2/IFITM2/HLA-H/IFI6/HLA-G/BST2/IFIT3/OASL/ISG20/ABCE1/HLA-E/SCRIB/IFITM3/IRAK1/IFITM1/IRF3/SAMHD1/OAS1/CNOT7/YTHDF3/IFI35/IFIT2/STAT1/IP6K2/JAK1	38
BP	GO:0071357	cellular response to type I interferon	38/4749	95/18670	0.001265	0.01821	0.01482	EGR1/IRF7/IFIT1/PTPN6/IRF4/ISG15/TREX1/OAS2/GBP2/MX1/IRF5/PTPN1/MMP12/RSAD2/IFITM2/HLA-H/IFI6/HLA-G/BST2/IFIT3/OASL/ISG20/ABCE1/HLA-E/SCRIB/IFITM3/IRAK1/IFITM1/IRF3/SAMHD1/OAS1/CNOT7/YTHDF3/IFI35/IFIT2/STAT1/IP6K2/JAK1	38
BP	GO:0070671	response to interleukin-12	23/4749	50/18670	0.00129	0.01853	0.01507	LMNB1/IL10/SIRPA/ANXA2/PITPNA/PDCD4/HSPA9/IL12RB2/GSTO1/CD47/CFL1/IL12RB1/RALA/CAPZA1/STAT4/MTAP/PSME2/RIPK2/CNN2/PLCB1/CDC42/PAK2/JAK1	23
BP	GO:0006470	protein dephosphorylation	106/4749	321/18670	0.001313	0.01882	0.01531	PTPN13/DUSP10/DUSP4/CDKN3/PTPRF/PTPN6/DLGAP5/PPM1N/DUSP6/CPPED1/PPP1R14A/PTPN7/SBF1/LGALS3/CDC25A/YWHAE/MTMR3/PPP2R1A/PPP1R14B/TNF/PPP1CB/PTPN1/CDC25C/SPPL3/PPTC7/MTOR/PTPN14/SWAP70/CDCA2/DAPP1/B3GAT3/DUSP5/PTBP1/PDXP/PALD1/CD33/URI1/BOD1/IGFBP3/HTT/PTPN4/PTPN9/EYA2/LHPP/PHACTR2/DUSP16/PINK1/PTPRC/TIMM50/ITGA1/DUSP23/DUSP22/TIPRL/PPP2CA/LILRB2/FKBP1A/GBA/PTPN18/PPP1R3E/GNAI2/STYXL1/PPP1R16B/PPA2/CAMTA1/PPP5C/PPM1G/FBXW11/RPRD1A/TAB1/DNAJC6/CAMK2G/PTPRM/PHLPP1/MGAT5/PTPMT1/MTMR14/BTRC/PPP1R8/DUSP18/DUPD1/PPP1R26/CDC14B/PTPRS/SSH2/ACP1/PPP2R3B/DUSP14/PPP1R15A/PPP1R9B/PPP6C/PPM1J/PPM1K/MYH6/SLC39A10/TGFB1/PPP1R12A/PGAM5/CDC25B/PPP1R2/CDH5/PPM1L/PPP6R1/PPP1R3B/PTP4A3/FAM220A/DUSP1	106
BP	GO:0001701	in utero embryonic development	121/4749	373/18670	0.001316	0.01882	0.01531	TWIST1/LIF/SKIL/VEGFA/NOTCH1/E2F7/E2F8/JAG2/STIL/CSF2/ASF1B/RBBP8/FOSL1/KLF2/IL10/SLC39A1/SRF/NEK2/PHLDA2/UBE2A/CCNB2/MYO1E/PLCD3/ATP11A/PRDM1/PLK4/PTCH1/SEC24D/ST14/MYH10/BRCA2/UBE2B/NASP/MSX1/VASH1/CCNB1/SOCS3/SNAI1/RIC8A/PELO/SMG9/GINS1/TGFB3/KAT2A/RBPJ/PKD2/GINS4/CMIP/AMOT/ACTL6A/BCOR/SPINT1/STMN3/APBA2/NMT1/RUNDC1/BYSL/NXN/STK3/SALL4/ZFP14/RBM46/CNOT3/PCDH12/NRK/TCTN1/SUPT6H/TANC2/SBDS/PTPN18/OTUD7B/RXRA/SOX8/ERCC2/EPB41L5/GGNBP2/TAB1/HS6ST1/WDR19/EPAS1/CEBPB/DHX35/BCL2L1/EMG1/TFEB/PSPH/KRT19/ZNF830/PRPF19/NPAT/DNAJB6/ADM/GABPA/RSPO3/EIF4E2/MYH9/POLG2/ZFP36L1/ELL/TRAF6/ADCY9/TPM1/MYO18B/C6/PLOD3/TIE1/FZD5/ARNT2/KDM4C/MYH6/NSUN2/CUL4A/MAPK1/RDH10/SYF2/PDGFB/UNK/GATA3/ANKRD11/SSR2/GCM1	121
BP	GO:1902099	regulation of metaphase/anaphase transition of cell cycle	24/4749	53/18670	0.001339	0.01899	0.01545	ESPL1/CENPF/AURKB/BUB1B/TTK/CDT1/TRIP13/CDC20/DLGAP5/BUB1/CDC6/PLK1/CCNB1/CENPE/FBXO5/NDC80/ANAPC11/USP44/XRCC3/MAD2L2/KLHL22/APC/ATM/DUSP1	24
BP	GO:0000727	double-strand break repair via break-induced replication	8/4749	11/18670	0.00134	0.01899	0.01545	MCM4/MCM5/MCM2/CDC45/GINS2/GINS4/MCM7/MCM3	8
BP	GO:0045628	regulation of T-helper 2 cell differentiation	8/4749	11/18670	0.00134	0.01899	0.01545	CD86/IL18/NLRP3/BCL6/TNFSF4/IL4R/HLX/RARA	8
BP	GO:0070757	interleukin-35-mediated signaling pathway	8/4749	11/18670	0.00134	0.01899	0.01545	EBI3/STAT3/IL12RB2/IL27RA/STAT4/CANX/STAT1/JAK1	8
BP	GO:0030522	intracellular receptor signaling pathway	94/4749	280/18670	0.001346	0.01903	0.01548	VDR/NR4A1/TWIST1/IRF7/NR4A3/PPARG/KANK2/PMEPA1/PTGIS/CBFB/TIFA/YWHAH/DNAJA1/CYP7B1/TGFB1I1/TP63/PML/THRA/HSPA1A/TLR4/ESRRA/STAT3/NR3C1/ASXL2/PIM1/SRC/SEC14L1/PPARGC1B/FABP5/TRIP4/UBB/CRY1/PAK1/UBE2N/MAP2K6/CYP26C1/NPLOC4/RPS27A/RORC/CARM1/CDK7/SMARCA4/PIAS1/CYLD/EZH2/ACTN4/UBA52/PRCP/NOD2/STARD10/IRAK1/ASXL1/SLA2/RXRA/ARID1A/PARK7/CYP27B1/PPP5C/UBE3A/NCOA4/DDX17/TAB1/NFKBIA/DDX54/CITED2/PIAS2/ARNTL/IRF3/YAP1/BIRC3/PADI2/FAM120B/SFRP1/TAF7/RIPK2/ESR1/DCBLD2/DEFA1B/C1QBP/TRAF6/TSPAN6/LBH/PPARD/ANKRD17/STRN3/NR2C1/ZCCHC3/RARA/TRIM16/DHRS3/USP17L2/NCOR1/TRIM15/SIRT1	94
BP	GO:0009144	purine nucleoside triphosphate metabolic process	112/4749	342/18670	0.001354	0.0191	0.01554	PPIF/CDK1/TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/COX8A/GPI/CBFA2T3/SIRT6/HK2/HSPA1A/NUP98/CTNS/SLC25A23/ENTPD5/ABCD1/DNAJC30/STAT3/TSPO/FXN/CCNB1/NUDT16/NUDT1/PGM2L1/PKM/AK5/ALDOC/VCP/OGDH/HTR2A/NDUFB11/COX6A1/PFKFB4/UQCRC1/SLC25A25/NUP153/FAM20C/AK3/NDUFB8/NME4/ATP1B1/BID/PINK1/DDIT4/NADK/ATP6V1A/VPS9D1/FIGNL1/GALK1/PFKFB2/NDUFS1/NUP88/ENO3/PRKAG2/NME3/NDUFS7/MYH7/PARK7/POM121C/NDUFB10/AK4/MYH4/NUP205/RAE1/MOCS1/NUP50/NDUFC1/SAMHD1/IMPDH1/NDUFA9/COX4I1/UQCR11/RAB23/ALDOA/GUK1/AMPD3/IL4/ISCU/NDUFA12/AK1/INSR/NUPR1/SPHK2/NUP93/PFKL/NFS1/ALDOB/NUP35/NME9/AAAS/OLA1/TAZ/AK2/NDUFA4/MYH6/NDUFB2/TGFB1/NDUFA13/NMNAT1/NUP62/P2RX7/SEH1L/NCOR1/BAD/NME2	112
BP	GO:0010332	response to gamma radiation	25/4749	56/18670	0.001377	0.01935	0.01574	EGR1/CDKN1A/TREX1/PML/HSPA5/BRCA2/BAX/CXCL10/GPX1/RPL26/XRCC6/PTPRC/TRIM13/BAK1/ELK1/BCL2L1/CYBA/YAP1/ATR/CHEK2/GTF2H5/CCL7/ATM/WRN/GATA3	25
BP	GO:0072528	pyrimidine-containing compound biosynthetic process	25/4749	56/18670	0.001377	0.01935	0.01574	TYMP/TYMS/DHODH/AGPAT3/TK1/MTOR/TPK1/AGPAT2/CMPK2/ERH/DTYMK/AK5/NME4/UPRT/DCTD/NME3/TAMM41/LCLAT1/CMPK1/CTPS2/UCK2/PRPS1/NME9/GPAT2/NME2	25
BP	GO:0043900	regulation of multi-organism process	130/4749	405/18670	0.001399	0.01961	0.01596	IL1B/NOTCH1/TOP2A/AURKA/CSF1R/TRIB1/IFIT1/TSPAN32/ISG15/GAPDH/GRN/CLEC7A/ANXA2P2/LGALS9/APOBEC3H/PPP2R1A/PML/SMC3/CHMP2B/KPNA2/MX1/PQBP1/TNF/ZFP36/GSN/IL2RA/LILRA2/TRIM25/ANXA2/TRIM26/SMARCB1/IFIT5/MMP12/HYAL3/RSAD2/SNF8/ASTL/FCN1/IFITM2/DTX3L/SEC14L1/PPIH/TRIM62/CCL3/BST2/MORC2/HAVCR2/CD74/OASL/LGALS1/PPP2R3C/CD180/NPLOC4/ISG20/OVGP1/PGLYRP3/SMARCA4/SIGIRR/TBC1D20/PRKCA/FUCA2/CFL1/TRIM13/TRIM44/BANF1/SP1/IL12RB1/IFITM3/AICDA/IFITM1/ARG1/CNR1/POLR2I/MID2/RNF216/JUN/FMR1/ACVR1C/TAF11/TIMP1/CCNK/RAD23A/DEFB114/SYT11/ZNF639/NFKBIL1/CYBA/POLR2C/ZC3H12A/PAEP/LACRT/BIRC3/OAS1/CNOT7/IFI16/SIRT2/ILF3/RIPK2/ZC3HAV1/LRSAM1/P2RY1/C1QBP/KRT6A/CHMP2A/STAU1/KLK5/TRAF6/POLR2J/TRIM35/TSPAN6/STAT1/CARD8/STOM/NUCKS1/HTRA1/ANKRD17/PLCB1/SIGLEC11/POLR2A/PLB1/ZCCHC3/SETDB1/PTAFR/USP17L2/P2RX7/CHMP3/BAD/TRIM15/IL23A/TRIM5	130
BP	GO:0071156	regulation of cell cycle arrest	42/4749	108/18670	0.001403	0.01962	0.01596	GTSE1/E2F7/E2F8/TP73/FOXM1/CDK1/CDKN1A/AURKA/ZNF385A/CDK5/PML/E2F1/PLK2/BAX/CDC25C/GADD45A/ZBTB17/CCNB1/SFN/RPL26/CDK2/PKD2/CARM1/RPL23/CNOT3/TFDP2/MUC1/MDM4/CCNK/MYBBP1A/RBL2/CNOT7/CRLF3/GML/FZD9/CHEK2/RRP8/UHRF2/ATM/TGFB1/POU4F1/CCND1	42
BP	GO:0042130	negative regulation of T cell proliferation	26/4749	59/18670	0.001406	0.01962	0.01596	CD86/SDC4/IL10/CD80/PTPN6/GPNMB/LGALS9/IL2RA/BTN2A2/TNFRSF21/FOXP3/CTLA4/HLA-G/HAVCR2/CLEC4G/LILRB2/ARG1/ERBB2/CEBPB/IDO1/PDCD1LG2/DLG5/PRNP/TGFB1/GLMN/LRRC32	26
BP	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	32/4749	77/18670	0.001415	0.0197	0.01603	EGR1/VEGFA/NOTCH1/LIMD1/PSMD8/UBB/PSMD1/PSMD2/RBPJ/PSMF1/RPS27A/UBA52/PSMD9/PSMA5/PSMB7/HIF3A/EPAS1/PSMD5/CITED2/PSME2/SIRT2/PSMB5/PSMB4/PSMA3/HIF1AN/BACH1/PSMD10/PSMB1/PSMD7/PSMB3/PSMC5/PSMD11	32
BP	GO:0001838	embryonic epithelial tube formation	47/4749	124/18670	0.001433	0.01991	0.0162	TWIST1/SDC4/STIL/MTHFD1L/LUZP1/KIF20B/PLXNB2/PTCH1/ST14/SEMA4C/SKI/ALX1/CTHRC1/DVL3/FZD6/PTK7/KAT2A/LMO4/ARHGAP35/SPINT1/STK3/LIAS/SALL4/VASP/IFT122/CFL1/TCTN1/DVL1/MTHFD1/SCRIB/IFT172/RALA/SOX8/GDF7/ARID1A/SOX11/SHROOM3/SFRP1/ADM/LRP6/PRKACB/TRAF6/MED12/TGFB1/GLMN/RARA/GATA3	47
BP	GO:0033047	regulation of mitotic sister chromatid segregation	29/4749	68/18670	0.001439	0.01996	0.01624	ESPL1/CENPF/AURKB/BUB1B/TTK/CDT1/TRIP13/CDC20/PTTG1/DLGAP5/BUB1/TACC3/CDC6/PLK1/CCNB1/CENPE/FBXO5/NUMA1/NDC80/ANAPC11/USP44/ANAPC1/XRCC3/MAD2L2/KLHL22/APC/ATM/SMC5/DUSP1	29
BP	GO:0043011	myeloid dendritic cell differentiation	11/4749	18/18670	0.001444	0.01998	0.01626	RELB/CSF2/BATF/IRF4/SPI1/UBD/RBPJ/IL4/DHRS2/TRAF6/TGFB1	11
BP	GO:0042176	regulation of protein catabolic process	123/4749	381/18670	0.001469	0.0202	0.01643	IL1B/PBK/RNF144A/FURIN/FAM83D/DTL/AURKA/IL10/TRIB1/TIMP4/CTSA/TIMP2/ANXA2P2/SGSM3/PML/SNX9/CBFA2T3/TNF/HSPA1A/PLK2/ECSCR/PLK1/DET1/ANXA2/LDLR/GPX1/WNT10B/SNF8/SMAD7/SORL1/RYBP/STX5/RPL5/NKD1/VCP/SDCBP/ATP13A2/CST3/CLU/USP19/UBB/PSMD1/PSMD2/MAGEF1/HERPUD1/MYLIP/PSMF1/N4BP1/UBXN1/IRAK3/FOXO1/RNF40/PDCL3/SGTA/SMURF1/RPL23/PINK1/UBE2G2/OAZ3/PIAS1/EZR/BCAP31/ATRAID/RAD23B/DVL1/LRP1/GBA/HGS/MDM4/SUMO1/EEF1A1/RNF19B/RHBDD3/PARK7/FMR1/UBE3A/TIMP1/AGAP2/TNFSF12/OAZ2/RAD23A/SCO1/ASB11/SNX33/EDEM2/SNX12/USP5/ARNTL/UCHL5/EEF1A2/GSK3A/PSME2/BRSK2/BTRC/UBQLN2/BAG2/SIRT2/ZFAND2A/TNFRSF1B/ATG4B/RNF139/GCLC/MAD2L2/TIMP3/CHEK2/MAP1A/NUPR1/OSBPL7/APC/RPL11/FBXL20/OAZ1/PSMD10/ATG7/GLMN/TMF1/NDUFA13/DNAJB2/ADAM9/UBAC2/FYN/BARD1/TRIB3	123
BP	GO:0045089	positive regulation of innate immune response	123/4749	381/18670	0.001469	0.0202	0.01643	IRF7/GRAMD4/RELB/HMGB3/TYRO3/IL21/HCK/CLEC10A/IRF4/TLR8/HEXIM1/TIRAP/TIFA/CLEC7A/PSPC1/SFPQ/ULBP2/UNC93B1/HMGB1/PQBP1/HSPA1A/TLR4/LILRA2/RAET1E/MMP12/CARD9/RSAD2/FFAR2/FCN1/SRC/SEC14L1/HLA-G/PSMD8/SH2D1A/BTK/HAVCR2/UBB/PSMD1/PSMD2/PAK1/TRIL/CD1D/XRCC6/UBE2N/MAP2K6/CTSB/PSMF1/IRAK3/NPLOC4/RPS27A/PAK3/PGLYRP3/LRRC14/CD300LF/RPS19/CYLD/HLA-E/RFTN1/UBA52/TLR2/FLOT1/MUC1/MICA/NOD2/PSMD9/TXK/TANK/IRAK1/PSMA5/LAG3/CADM1/TLR6/MNDA/FPR2/CLEC4D/PSMB7/ICAM2/FBXW11/TAB1/NFKBIA/PRKCE/PSMD5/NFKBIL1/CYBA/IRF3/BIRC3/PSME2/TNIP3/BTRC/IFI16/CARD11/LAMP1/PIK3C3/S100A8/PSMB5/RIPK2/ESR1/ULBP1/MAPKAPK2/PTPRS/COLEC12/PRKACB/PSMB4/C1QBP/TRAF6/PSMA3/PIK3R4/TSPAN6/ANKRD17/PSMD10/PSMB1/PSMD7/PSMB3/ZCCHC3/KLRK1/PSMC5/USP17L2/FYN/PAK2/PJA2/TRIM15/PSMD11/TRIM5	123
BP	GO:0072525	pyridine-containing compound biosynthetic process	55/4749	150/18670	0.001472	0.0202	0.01643	TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/PTGIS/ENO1/PGAM1/PFKP/GPI/CBFA2T3/SIRT6/HK2/NUP98/ENTPD5/STAT3/PGM2L1/PKM/ALDOC/OGDH/HTR2A/PFKFB4/NUP153/NAMPT/DDIT4/NADK/GALK1/PARP16/PFKFB2/NUP88/ENO3/PRKAG2/POM121C/NUP205/RAE1/IDO1/NUP50/ALDOA/RNLS/INSR/NUPR1/NUP93/PFKL/ALDOB/NUP35/AAAS/NMNAT1/NMNAT3/NUP62/P2RX7/SEH1L/NCOR1/ASPDH	55
BP	GO:0071356	cellular response to tumor necrosis factor	97/4749	291/18670	0.001473	0.0202	0.01643	SGMS1/ICAM1/KLF2/TXNDC17/CCL20/CCL3L3/TNFRSF18/CCL22/TNFSF4/RFFL/GBP2/EDARADD/TNFRSF12A/TNF/ZFP36/TNFRSF4/HSPA1A/TNFRSF8/NOL3/PIAS3/TNFRSF21/BAG4/HYAL3/TRAIP/ARHGEF2/PSMD8/CLIP3/CCL3/PSMD1/PSMD2/LIMS1/KAT2A/RPS3/SLC2A4/PSMF1/CCL2/ZFP36L2/TNFRSF19/CCL17/MAP3K5/CYLD/TNFRSF9/ADAMTS13/CCL18/ACTN4/CD58/PSMD9/TANK/GBA/PSMA5/TNFRSF13B/LTA/PSMB7/TNFSF12/NFKBIA/TRAF1/PSMD5/TNFSF9/CYBA/ZC3H12A/BIRC3/PSME2/SFRP1/TRAF2/PIAS4/ST18/TNFSF13/ADIPOQ/TNFRSF11B/PSMB5/TNFRSF1B/ZFP36L1/PSMB4/CCL23/PSMA3/STAT1/CARD8/TNFSF11/EDAR/CCL7/ZNF675/PSMD10/CCL15/PSMB1/PSMD7/HAS2/COMMD7/PSMB3/SPATA2/MAPK1/PSMC5/GATA3/ILK/TNFRSF25/PSMD11/ZFAND6/SIRT1	97
BP	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	40/4749	102/18670	0.001496	0.02044	0.01663	PKMYT1/CCNF/CDKN1A/CDKN3/CDKN2B/CCNG2/CCNA2/HEXIM1/CCNB2/CDC25A/CDC6/PLK1/CDC25C/CDKN2C/GADD45A/PSRC1/CKS2/CCNB1/SRC/SFN/CKS1B/PKD2/CCNE2/CDK7/CCNT2/CDKN2A/CCNK/GTF2H1/CCNJ/CCNL2/MNAT1/CCNY/APC/SERTAD1/PSMD10/CCNC/CCNI/CCND1/PDGFB/ACTB	40
BP	GO:0002758	innate immune response-activating signal transduction	99/4749	298/18670	0.001496	0.02044	0.01663	IRF7/GRAMD4/RELB/TYRO3/HCK/CLEC10A/IRF4/TLR8/TIRAP/TIFA/CLEC7A/UNC93B1/HMGB1/HSPA1A/TLR4/LILRA2/CARD9/RSAD2/FFAR2/FCN1/SRC/SEC14L1/PSMD8/BTK/HAVCR2/UBB/PSMD1/PSMD2/PAK1/TRIL/UBE2N/MAP2K6/CTSB/PSMF1/IRAK3/NPLOC4/RPS27A/PAK3/PGLYRP3/LRRC14/CD300LF/CYLD/RFTN1/UBA52/TLR2/FLOT1/MUC1/NOD2/PSMD9/TANK/IRAK1/PSMA5/TLR6/CLEC4D/PSMB7/ICAM2/FBXW11/TAB1/NFKBIA/PRKCE/PSMD5/NFKBIL1/CYBA/IRF3/BIRC3/PSME2/TNIP3/BTRC/CARD11/PIK3C3/S100A8/PSMB5/RIPK2/ESR1/MAPKAPK2/PTPRS/COLEC12/PRKACB/PSMB4/C1QBP/TRAF6/PSMA3/PIK3R4/TSPAN6/ANKRD17/PSMD10/PSMB1/PSMD7/PSMB3/ZCCHC3/KLRK1/PSMC5/USP17L2/FYN/PAK2/PJA2/TRIM15/PSMD11/TRIM5	99
BP	GO:0072330	monocarboxylic acid biosynthetic process	112/4749	343/18670	0.001514	0.02064	0.01679	IL1B/HSD3B7/TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/CH25H/PTGIS/ALOX5AP/ENO1/CYP7B1/PGAM1/CEACAM1/PFKP/ACSM3/ACOT11/GPI/CBFA2T3/SIRT6/HK2/FADS3/NUP98/ENTPD5/TECR/SDS/ABCD1/STAT3/MYO5A/MECR/SCD/FA2H/ABCD2/PGM2L1/PKM/ABAT/FABP5/ALDOC/SLC27A2/OGDH/HTR2A/MCAT/CD74/PFKFB4/PER2/ASNS/EPHX2/NUP153/ACOX2/TECRL/PRKAB2/HSD17B8/ACOT8/LIAS/DDIT4/ADIPOR2/GALK1/PFKFB2/ALOX5/SLC45A3/INSIG1/NUP88/ADIPOR1/ENO3/PRKAG2/GPX4/TBXAS1/AMACR/PARK7/ELOVL7/POM121C/DSEL/PIBF1/PTGES2/NUP205/RAE1/ELOVL1/IDO1/NUP50/ASAH2/ABHD1/ALDOA/ADIPOQ/OXSM/ASAH2B/ACACB/ACSS1/FASN/INSR/NUPR1/OSBPL7/CYP2D6/NUP93/HPGD/PFKL/ALDOB/NUP35/PECR/AAAS/CYP7A1/RDH10/NUP62/P2RX7/SEH1L/NCOR1/ASNSD1/DECR2/OSBPL9/TRIB3/SIRT1	112
BP	GO:0033048	negative regulation of mitotic sister chromatid segregation	20/4749	42/18670	0.001557	0.02118	0.01723	CENPF/AURKB/BUB1B/TTK/CDT1/TRIP13/CDC20/PTTG1/BUB1/PLK1/CCNB1/FBXO5/NDC80/USP44/XRCC3/MAD2L2/KLHL22/APC/ATM/DUSP1	20
BP	GO:0044282	small molecule catabolic process	141/4749	445/18670	0.001601	0.02174	0.01768	TWIST1/BCAT1/HSD3B7/IL4I1/TPI1/GK/GAPDH/HK1/ENTPD1/TYMP/GLB1/ENO1/PGAM1/PFKP/APOBEC3H/GPI/HK2/ABHD16A/DDAH2/ENTPD5/MTOR/ADTRP/SDS/ABCD1/BCKDK/APOBEC3B/MPST/HYAL3/CARNS1/TST/NUDT16/MECR/NUDT1/ABCD2/GLS2/PGM2L1/PKM/ABAT/GLDC/IDUA/AIG1/ALDOC/SLC27A2/OGDH/AMDHD1/PDXP/MCAT/MTHFS/HPRT1/SARDH/ENTPD2/HMGCL/ALDH2/GPT/GLYATL2/ACOX2/CYP26C1/CTH/TYSND1/GCAT/PNP/GALK2/IMPA2/ACOT8/ENOSF1/OXCT1/GNPDA1/SCARF1/OXCT2/GALK1/DLST/ADPRM/PFKFB2/ATP2B4/AICDA/ENO3/ARG1/CNR1/NTSR1/CHP1/AMACR/ENPP4/CYP27B1/ETFA/PEX2/GALM/CD44/MTRR/INPP1/IDO1/DPYD/BDH2/GLUD1/PLA2G15/GSK3A/ENTPD4/NUDT3/ABHD1/FAH/ALDOA/CYP4F12/ADIPOQ/CPT1A/ALDH3B1/SLC27A4/ACACB/NT5E/HGD/FUT6/ETFB/HIBADH/RPE/PCCB/ACAD11/GPT2/HEXB/GALT/GUSB/ALDH7A1/AMT/ECI1/PFKL/NUDT19/ALDOB/PGD/PECR/PPARD/CYP7A1/PPM1K/PEX13/TGFB1/ALDH5A1/HADHB/GSTZ1/NAGK/ADHFE1/SESN2/AKR1A1/LPIN1/BAD/DECR2	141
BP	GO:0051985	negative regulation of chromosome segregation	21/4749	45/18670	0.001652	0.02231	0.01815	ESPL1/CENPF/AURKB/BUB1B/TTK/CDT1/TRIP13/CDC20/PTTG1/BUB1/PLK1/CCNB1/FBXO5/NDC80/USP44/XRCC3/MAD2L2/KLHL22/APC/ATM/DUSP1	21
BP	GO:0006643	membrane lipid metabolic process	72/4749	207/18670	0.001654	0.02231	0.01815	B3GNT5/SGMS1/NAGA/CTSA/NEU4/GLB1/GBGT1/SPTSSA/SGMS2/KDSR/PPP2R1A/SERINC3/TNF/PDXDC1/GM2A/NEU1/BAX/ITGB8/TECR/FA2H/P2RX1/PIGK/PPT1/PIGH/SGPP1/DPM2/ST8SIA1/PRKD3/GAL3ST2/SUMF1/ST6GALNAC4/PIGQ/PPP2CA/PIGO/GBA/ELOVL7/ACER1/ELOVL1/ACER2/PIGC/PLA2G15/ASAH2/PIGW/B4GALT5/ARV1/ALDH3B1/ASAH2B/ORMDL2/NEU3/MGST2/TEX2/FUT6/GALC/SPHK2/HEXB/GAL3ST4/PIGM/SUMF2/PIGA/AGK/ST8SIA3/FUCA1/ALDH5A1/CERS3/CSNK1G2/ST6GALNAC6/PPM1L/B4GALT4/P2RX7/PIGG/ORMDL3/PIGT	72
BP	GO:0006733	oxidoreduction coenzyme metabolic process	72/4749	207/18670	0.001654	0.02231	0.01815	TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/PTGIS/ENO1/PGAM1/PFKP/GPI/CBFA2T3/SIRT6/HK2/NUP98/FDXR/PPTC7/ENTPD5/TP53I3/STAT3/PGM2L1/PKM/ALDOC/VCP/OGDH/HTR2A/PDHB/PFKFB4/NUP153/PDHX/MDH2/NAMPT/DDIT4/NADK/GALK1/PARP16/PFKFB2/NUP88/ENO3/SHPK/PRKAG2/POM121C/NUP205/RAE1/NUDT17/IDO1/NUP50/NDUFA9/ALDOA/COQ10A/NT5E/FMO2/RNLS/NNT/RPE/INSR/NUPR1/NUP93/PFKL/ALDOB/NUP35/PGD/AAAS/MPC1/NMNAT1/NMNAT3/NUP62/P2RX7/SEH1L/NCOR1/ASPDH	72
BP	GO:0031334	positive regulation of protein complex assembly	90/4749	268/18670	0.001661	0.02235	0.01818	CXCL13/TWIST1/CDC42EP4/VEGFA/FSCN1/CSF2/CDT1/ICAM1/FOSL1/FES/SRF/HCK/RAC1/TTBK1/CYFIP1/CLEC7A/SNX9/DDB2/TNF/GSN/HSPA1A/TLR4/CTTN/BAX/PMAIP1/MTOR/WNT10B/BAG4/PSRC1/CDC42EP1/SRC/TPPP3/TPPP/TENM1/ARHGEF5/NUMA1/CORO1B/VCP/BMF/CLU/WHAMMP3/PAK1/PFN2/RPS3/HIP1R/MPP7/BIK/ARPC1B/CCK/TERF1/BID/PICK1/PINK1/CORO1A/VASP/ABCA1/ARPC5/PAN3/SUMO1/DHX33/TLR6/ERCC5/JUN/ERCC2/PIEZO1/GTF2H2/PRKCE/ACTR3B/GTF2H1/ESR1/FER/ATR/ARF6/GTF2H5/XPA/ARL2/WHAMM/ATM/AP1AR/SLAIN2/TGFB1/C15orf62/CUL4A/WAS/CDH5/FMN1/PSMC5/ERCC1/TRABD2B/RAC3	90
BP	GO:0030595	leukocyte chemotaxis	77/4749	224/18670	0.001696	0.02278	0.01853	CXCL13/IL1B/VEGFA/HSD3B7/WNK1/IL10/CCL20/CCL3L3/RAC1/IL1RN/CH25H/CSF3R/CCL22/TIRAP/CCR1/DAPK2/CYP7B1/LGALS3/LGALS9/HMGB1/CSF1/CXCL10/SERPINE1/FFAR2/SWAP70/CCR6/CCR2/ARHGEF5/SLC12A2/PDE4D/CCL3/PDE4B/CD74/CCR5/S1PR1/CCL2/PREX1/CCL17/RPS19/CORO1A/TRPM4/ITGA1/AIF1/CCL18/CXCL9/CXCL16/SBDS/FLT1/CXCL2/CXCL3/FPR2/GBF1/C3AR1/IL17RC/RAC2/PADI2/RARRES2/S100A8/CKLF/IL36A/DEFA1B/C1QBP/CCL23/TNFSF11/CCL7/PPBP/THBS4/DDT/CCL15/KLRK1/CXCR5/PDGFB/CCL27/VEGFC/IL37/IL23A/DUSP1	77
BP	GO:0051047	positive regulation of secretion	136/4749	428/18670	0.0017	0.02278	0.01853	TWIST1/IL1B/MAPK11/SDC4/NLRP3/ADORA2A/CSF1R/IL10/ABCG1/RAC1/TLR8/IL17A/GAPDH/HK1/NMB/TNFSF4/CDK5/SPP1/LGALS9/GPI/MYH10/HMGB1/TNF/TNFRSF4/BLK/TLR4/NCS1/LILRA2/GAB2/MMP12/HYAL3/IL4R/SNF8/FFAR2/FRMD4A/FCN1/SRC/ABAT/SYT4/ARRB1/CCL3/SDCBP/ATP13A2/PTGER4/STAM/HAVCR2/C2CD2L/SRI/CD33/TGFB3/CD177/RAB3D/MAP2K6/CCK/STXBP5/CASR/STX1B/SDC1/TCF7L2/PINK1/SPTBN1/EZR/TRPM4/CLASP2/NADK/HLA-E/AIF1/OXCT1/TLR2/KCNN4/PFKFB2/CD58/NOD2/PSMD9/LRP1/DTNBP1/IL26/OSM/HGS/CADM1/SIRT3/ILDR1/GNAI2/RAB27A/CNR1/NTSR1/C1QTNF3/UNC13D/IL17RC/PRKCE/TACR2/SOX11/CYBA/IRF3/GLUD1/PAEP/LILRA5/LACRT/IL13/CD2AP/LAMP1/IFNGR1/GHRL/S100A8/CD34/RIPK2/MYOM1/F2R/SERP1/DOC2B/CLEC5A/P2RY1/CHMP2A/RAB15/ARF6/SPHK2/CACNB2/CARD8/PARD6A/TNFSF11/FZD5/PPARD/FFAR1/TGFB1/GLMN/TMF1/ADAM9/TRIM16/GATA3/PTAFR/PDX1/P2RX7/GIPR/SYBU/VEGFC/BAD	136
BP	GO:0043254	regulation of protein complex assembly	147/4749	467/18670	0.00173	0.02314	0.01882	CXCL13/TWIST1/CDC42EP4/KIF14/VEGFA/HJURP/FSCN1/PLEKHG2/CSF2/CDT1/ICAM1/FOSL1/FES/SRF/HCK/RAC1/TTBK1/PMEPA1/CYFIP1/CLEC7A/THRA/SNX9/EIF4EBP1/CAPZB/DDB2/HMGB1/TNF/GSN/HSPA1A/TLR4/CTTN/BAX/PMAIP1/MTOR/MYADM/WNT10B/RANGRF/BAG4/PSRC1/CDC42EP1/SORL1/TMOD2/SRC/TPPP3/TPPP/TENM1/ARHGEF5/NUMA1/CAPG/ARHGEF2/TMC8/CLIP3/CORO1B/VCP/BMF/CLU/PTGER4/WHAMMP3/PAK1/ADD3/PFN2/RPS3/HIP1R/LMO4/MPP7/SMAD6/BIK/ARPC1B/CCK/PAK3/TERF1/PREX1/STX1B/BID/PICK1/TMSB4Y/PINK1/SPTBN1/CORO1A/STMN1/VASP/TRIOBP/TWF2/TFIP11/ABCA1/ULK1/COTL1/SPTAN1/ARPC5/MKKS/PAN3/INSIG1/GBA/SUMO1/DHX33/STYXL1/CAPZA1/TLR6/LDLRAD4/ERCC5/PARK7/JUN/ERCC2/TUBB4A/PIEZO1/GTF2H2/PRKCE/ACTR3B/KANK3/NLRC3/GTF2H1/TMSB15A/VILL/NAPB/SIRT2/PEX5/TAF7/ESR1/FER/ATR/ARF6/ARHGAP18/GTF2H5/RALB/XPA/ARL2/SENP6/WHAMM/ATM/AP1AR/SLAIN2/TGFB1/C15orf62/CDC42/CUL4A/WAS/ZNF451/TRAPPC12/CDH5/FMN1/PSMC5/CRBN/ADD2/ERCC1/TRIM9/TRABD2B/RAC3	147
BP	GO:0031396	regulation of protein ubiquitination	71/4749	204/18670	0.001741	0.02324	0.01891	NDFIP2/UBE2C/ISG15/CDC20/FANCI/CDK5/DNAJA1/GORASP1/UBE2S/HSPA5/HSPA1A/DERL1/ARRDC3/PLK1/MTOR/SMAD7/TSPO/DTX3L/RPL5/FBXO5/ARRB1/UBB/CRY1/HERPUD1/PER2/UBE2N/RPS3/N4BP1/UBXN1/RNF40/RPL23/PINK1/NXN/ARRDC4/TRIM44/NOD2/FKBP1A/FEM1B/LIMK1/CHP1/PARK7/UBE3A/RASD2/TOPORS/USP44/PRKCE/DCUN1D4/SIAH2/BIRC3/GSK3A/BAG2/CDC14B/RIPK2/GCLC/MAD2L2/TRAF6/BIRC7/MTA1/RAB1A/RPL11/WDR48/PSMD10/PHF23/GLMN/DNAJB2/BMI1/PEF1/FBXO4/FYN/TRIB3/MAGEA2B	71
BP	GO:0051168	nuclear export	68/4749	194/18670	0.001752	0.02331	0.01897	EGR2/IL1B/GTSE1/SEC13/U2AF1/CAMK1/CDK5/YWHAE/RBM22/NUP98/SMG5/POLDIP3/PTPN14/CSE1L/IWS1/SFN/HSPA9/RNPS1/RPS15/ENY2/SRSF4/NUP153/UPF1/MAGOHB/SMURF1/TCF7L2/DUSP16/ATXN1/ABCE1/STRADB/ALKBH5/SUPT6H/XPO6/NUP88/THOC3/CHP1/PARK7/EMD/U2AF1L4/POM121C/NUP205/RAE1/NUP50/BAG3/DHX38/SDAD1/MAGOH/CPSF1/UHMK1/SMG6/GLE1/CPSF6/NUP93/AKAP13/DDX19A/LSG1/CDC40/RBM27/NUP35/AAAS/NCBP2/TGFB1/CCHCR1/NUP62/SEH1L/YTHDC1/BARD1/NXF3	68
BP	GO:0045445	myoblast differentiation	34/4749	84/18670	0.001754	0.02331	0.01897	NOTCH1/IL18/SRF/MAML1/TNF/CXCL10/WNT10B/DTYMK/TRIP4/MAPK12/RBPJ/IGFBP3/LGALS1/JAG1/CCL17/SDC1/TCF7L2/MAP3K5/CXCL9/DDIT3/SOX8/PLEKHM3/DDX17/MBNL3/EPAS1/ZFP36L1/EID2B/HIF1AN/DLL1/PPARD/PLCB1/TGFB1/SRA1/ILK	34
BP	GO:0045066	regulatory T cell differentiation	17/4749	34/18670	0.001776	0.02351	0.01913	DUSP10/BCL6/TNFRSF18/CBFB/TNFSF4/LGALS9/IL2RA/BTN2A2/FOXP3/CTLA4/HLA-G/LILRB4/KAT2A/LILRB2/LAG3/CD46/TGFB1	17
BP	GO:0070670	response to interleukin-4	17/4749	34/18670	0.001776	0.02351	0.01913	MRC1/RPL3/TUBA1B/PML/HSPA5/IL4R/PARP14/MCM2/IL2RG/CD300LF/CORO1A/ADAMTS13/ARG1/SHPK/FASN/JAK3/GATA3	17
BP	GO:0009199	ribonucleoside triphosphate metabolic process	111/4749	341/18670	0.001783	0.02354	0.01915	PPIF/CDK1/TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/COX8A/GPI/CBFA2T3/SIRT6/HK2/HSPA1A/NUP98/CTNS/SLC25A23/ENTPD5/ABCD1/DNAJC30/STAT3/TSPO/FXN/CCNB1/PGM2L1/PKM/AK5/ALDOC/VCP/OGDH/HTR2A/NDUFB11/COX6A1/PFKFB4/UQCRC1/SLC25A25/NUP153/FAM20C/AK3/NDUFB8/NME4/ATP1B1/BID/PINK1/DDIT4/NADK/ATP6V1A/VPS9D1/FIGNL1/GALK1/PFKFB2/NDUFS1/NUP88/ENO3/PRKAG2/NME3/NDUFS7/MYH7/PARK7/POM121C/NDUFB10/AK4/MYH4/NUP205/RAE1/MOCS1/NUP50/NDUFC1/IMPDH1/NDUFA9/COX4I1/UQCR11/RAB23/ALDOA/GUK1/AMPD3/IL4/ISCU/NDUFA12/AK1/CTPS2/UCK2/INSR/NUPR1/SPHK2/NUP93/PFKL/NFS1/ALDOB/NUP35/NME9/AAAS/OLA1/TAZ/AK2/NDUFA4/MYH6/NDUFB2/TGFB1/NDUFA13/NMNAT1/NUP62/P2RX7/SEH1L/NCOR1/BAD/NME2	111
BP	GO:0002286	T cell activation involved in immune response	41/4749	106/18670	0.001791	0.02356	0.01917	CD86/IL18/RELB/NLRP3/ICAM1/BATF/CD80/IRF4/BCL3/BCL6/TNFSF4/LGALS3/CEACAM1/LGALS9/HMGB1/MTOR/FOXP3/CD1C/STAT3/IL4R/SMAD7/RPS6/PTGER4/HAVCR2/APBB1IP/LY9/HLX/RORC/IL12RB1/IL18R1/RAB27A/CD46/CLEC4D/HLA-DMB/ZC3H12A/RIPK2/JAK3/RARA/ZFPM1/GATA3/IL23A	41
BP	GO:1904029	regulation of cyclin-dependent protein kinase activity	41/4749	106/18670	0.001791	0.02356	0.01917	PKMYT1/CCNF/CDKN1A/CDKN3/CDKN2B/TTBK1/CCNG2/CCNA2/HEXIM1/CCNB2/CDC25A/CDC6/PLK1/CDC25C/CDKN2C/GADD45A/PSRC1/CKS2/CCNB1/SRC/SFN/CKS1B/PKD2/CCNE2/CDK7/CCNT2/CDKN2A/CCNK/GTF2H1/CCNJ/CCNL2/MNAT1/CCNY/APC/SERTAD1/PSMD10/CCNC/CCNI/CCND1/PDGFB/ACTB	41
BP	GO:0032635	interleukin-6 production	58/4749	161/18670	0.001797	0.02359	0.0192	TWIST1/IL1B/IL18/KLF2/IL10/PTPN6/TLR8/IL17A/IL1RN/SIRPA/TIRAP/TNFSF4/CLEC7A/LGALS9/HMGB1/TNF/CD200/TLR4/LILRA2/FOXP3/CARD9/STAT3/ARHGEF2/ARRB1/HAVCR2/CD74/IRAK3/CD47/AIF1/TLR2/NOD2/LILRB2/GBA/IL27RA/C1QTNF3/TLR6/IL17RC/SYT11/AZI2/CEBPB/CYBA/NLRC3/ZC3H12A/PAEP/RABGEF1/LILRA5/GHRL/RIPK2/F2R/MAPKAPK2/TYROBP/IL36A/AKIRIN2/TRAF6/SPHK2/PTAFR/P2RX7/IL37	58
BP	GO:0070911	global genome nucleotide-excision repair	14/4749	26/18670	0.001818	0.02381	0.01937	DDB2/UBB/RPS27A/RAD23B/UBA52/ERCC2/GTF2H2/GTF2H1/USP45/CETN2/GTF2H5/XPA/CUL4A/ERCC1	14
BP	GO:0070664	negative regulation of leukocyte proliferation	32/4749	78/18670	0.001821	0.02381	0.01937	CD86/SDC4/IL10/CD80/PTPN6/GPNMB/LGALS9/IL2RA/BTN2A2/TNFRSF21/FOXP3/CTLA4/HLA-G/BTK/HAVCR2/CLEC4G/LILRB2/ARG1/TNFRSF13B/MNDA/ERBB2/CEBPB/IDO1/SOX11/PDCD1LG2/DLG5/PRNP/TYROBP/ATM/TGFB1/GLMN/LRRC32	32
BP	GO:0051054	positive regulation of DNA metabolic process	78/4749	228/18670	0.001847	0.02398	0.01951	AURKB/E2F7/E2F8/FOXM1/CDK1/CDT1/KLF4/NEK2/RAC1/TNFSF4/TFRC/PARM1/PML/HMGB1/SIRT6/BAX/UBE2B/USP9X/RAD51/NUDT16/SRC/DTX3L/DBF4/TNFAIP1/DBF4B/TP53BP1/CDK2/MORC2/UBE2N/RPS3/RFC2/CCT5/EYA2/PAK3/CBX8/ZNF304/PTPRC/DSCC1/ERCC8/TIMELESS/TNKS2/ACD/CTC1/CHTF8/GNL3/RNF8/BRCC3/JUN/ERCC2/APLF/MAP2K4/POT1/XRCC1/WRAP53/DDX11/DNA2/TNFSF13/IL4/KCTD13/MAD2L2/ATR/FAM168A/ATM/WIZ/WRN/TGFB1/WAS/MGMT/MAPK1/PPHLN1/HDAC10/SETDB1/PDGFB/ERCC1/FBXO4/RNF168/CCT3/SIRT1	78
BP	GO:0002200	somatic diversification of immune receptors	31/4749	75/18670	0.001849	0.02398	0.01951	IL10/BATF/EXO1/BCL6/TNFSF4/TFRC/HMGB1/MSH6/FOXP3/PMS2P1/SWAP70/CCR6/TP53BP1/POLQ/PTPRC/SUPT6H/AICDA/IL27RA/RNF8/PMS2P5/APLF/SAMHD1/POLM/TNFSF13/IL4/MAD2L2/ATM/RAG2/TGFB1/ERCC1/RNF168	31
BP	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	31/4749	75/18670	0.001849	0.02398	0.01951	FCGR1B/NCF4/CYBB/FCGR1A/HLA-H/CD207/HLA-G/PSMD8/PSMD1/PSMD2/PSMF1/HLA-E/PSMD9/SNAP23/PSMA5/TAP1/PSMB7/VAMP3/PSMD5/CYBA/PSME2/PSMB5/PSMB4/PSMA3/NCF1/PSMD10/PSMB1/PSMD7/PSMB3/PSMC5/PSMD11	31
BP	GO:0051303	establishment of chromosome localization	31/4749	75/18670	0.001849	0.02398	0.01951	CENPF/KIF2C/CDCA8/KIF14/KIFC1/CDCA5/FAM83D/GEM/CDT1/DLGAP5/SPAG5/KIF18A/CHMP2B/NUF2/UBE2B/PSRC1/CCNB1/CENPE/NUMA1/NDC80/BOD1/TERF1/TTL/PIBF1/CHMP1A/CHMP2A/CHAMP1/ATM/TRAPPC12/NUP62/SEH1L	31
BP	GO:0051881	regulation of mitochondrial membrane potential	30/4749	72/18670	0.001871	0.02421	0.0197	ADORA2A/BNIP3L/MLLT11/PRELID1/BAX/CTNS/PMAIP1/ABCD1/CLIC1/TSPO/SRC/IFI6/PRDX3/VCP/UBB/PPP2R3C/CCK/BID/PINK1/NDUFS1/BAK1/PPA2/PARK7/BCL2L1/SLC25A36/FZD9/GCLC/NNT/P2RX7/BAD	30
BP	GO:0051382	kinetochore assembly	10/4749	16/18670	0.001888	0.02439	0.01984	CENPF/CENPA/CENPW/CENPE/CENPT/CENPN/SENP6/POGZ/TRAPPC12/CENPK	10
BP	GO:0045428	regulation of nitric oxide biosynthetic process	28/4749	66/18670	0.001896	0.02444	0.01988	IL1B/ICAM1/KLF2/IL10/ACP5/KLF4/RAC1/PTGIS/SIRPA/CLEC7A/TNF/TLR4/DDAH2/MTOR/TSPO/CLU/PKD2/CD47/AIF1/ATP2B4/TLR6/ZC3H12A/CD34/HBB/INSR/KLRK1/CX3CR1/KHSRP	28
BP	GO:0002791	regulation of peptide secretion	156/4749	500/18670	0.001911	0.02458	0.02	TWIST1/IL1B/MAPK11/NLRP3/ADORA2A/CSF1R/IL10/ABCG1/RAC1/TLR8/IL17A/GAPDH/HK1/PIM3/RAB11FIP1/SLC16A1/TNFSF4/LGALS9/PML/GPI/MYH10/HMGB1/TNF/TNFRSF4/CD200/BLK/TLR4/BTN2A2/LILRA2/TNFRSF21/FOXP3/ADTRP/MMP12/IL1R2/IL4R/RSAD2/FFAR2/FRMD4A/FCN1/SRC/TIAM1/ABAT/SYT4/PAM/ARRB1/CCL3/ATP13A2/PTGER4/ENY2/HAVCR2/C2CD2L/SRI/CD33/TGFB3/CD74/ENHO/PER2/FFAR3/CASR/TCF7L2/SPTBN1/EZR/PRKCA/TRPM4/NADK/HLA-E/AIF1/ANXA5/OXCT1/TLR2/KCNN4/PFKFB2/CD58/NOD2/PSMD9/LRP1/IL27RA/IL26/OSM/CADM1/CACNA2D2/SIRT3/ILDR1/CNR1/C1QTNF3/TLR6/RHBDD3/TFAP2B/RAB11FIP3/ACVR1C/SLC25A5/IL17RC/ANXA4/DEFB114/SYT11/PRKCE/SIDT2/LRP5L/ARNTL/SRGN/IRF3/GLUD1/ZC3H12A/PAEP/RABGEF1/LILRA5/BRSK2/IL13/KRT20/SFRP1/TRAF2/CD2AP/PIK3C3/IFNGR1/GHRL/KCNG2/S100A8/CPT1A/CD34/ARL2BP/RIPK2/TNFRSF1B/MYOM1/RAB11FIP5/F2R/SERP1/DOC2B/CLEC5A/TRAF6/ARF6/HDAC9/SLC25A4/CARD8/PARD6A/PFKL/TNFSF11/ARL2/FZD5/NPFF/PPARD/SLC9B2/FFAR1/TGFB1/GLMN/ADAM9/NDUFAF2/TRIM16/GATA3/PDX1/P2RX7/GIPR/LRRC32/SYBU/VEGFC/BAD/GJA5	156
BP	GO:0002181	cytoplasmic translation	39/4749	100/18670	0.001916	0.0246	0.02001	TICRR/ZNF385A/EIF4EBP1/RPL32/RPL10A/MTOR/RPL38/RPL19/DPH5/RPL36/RPL30/RPL26/RPS23/RPL36A/RPL18A/RPL6/EIF3I/DPH1/CNBP/EIF4H/DRG2/FMR1/RPL29/EIF3L/RPSA/EIF3H/EIF2D/EIF2S3/RPS28/EIF3G/DNAJC24/RPL39/CPEB1/HSPA14/DENR/GSPT1/RPL11/EIF3E/UNK	39
BP	GO:0072175	epithelial tube formation	49/4749	132/18670	0.001924	0.02465	0.02006	TWIST1/SDC4/STIL/MTHFD1L/LUZP1/KIF20B/PLXNB2/PTCH1/ST14/SEMA4C/SKI/ALX1/CTHRC1/DVL3/FZD6/PTK7/KAT2A/LMO4/ARHGAP35/SPINT1/STK3/LIAS/SALL4/VASP/IFT122/CFL1/TCTN1/DVL1/MTHFD1/SCRIB/IFT172/RALA/SOX8/GDF7/ARID1A/SOX11/SHROOM3/SFRP1/ADM/LRP6/PRKACB/TRAF6/FGF8/MED12/TGFB1/TCAP/GLMN/RARA/GATA3	49
BP	GO:0051258	protein polymerization	94/4749	283/18670	0.001947	0.02489	0.02025	CDC42EP4/UBE2C/PLEKHG2/ICAM1/FES/HCK/RAC1/TTBK1/CYFIP1/MSRB1/UBE2S/SNX9/CAPZB/MX1/GSN/HSPA1A/CTTN/CENPJ/MTOR/MYADM/RANGRF/BAG4/PSRC1/CDC42EP1/TMOD2/TPPP3/TPPP/TENM1/FBXO5/NUMA1/CAPG/CLIP3/CORO1B/WHAMMP3/PAK1/ADD3/PFN2/RPS3/HIP1R/ARPC1B/PAK3/TERF1/PREX1/TUBGCP2/PICK1/TMSB4Y/PINK1/SPTBN1/FGF13/CORO1A/STMN1/CLASP2/VASP/AIF1/TRIOBP/TWF2/DIAPH3/COTL1/VTN/SPTAN1/ARPC5/TUBG2/MKKS/GPX4/CAPZA1/TUBB4A/CEP192/PRKCE/ACTR3B/KANK3/CORO7/TMSB15A/VILL/FER/TUBG1/CHMP2A/ARF6/ARHGAP18/PSTPIP2/NEFL/ARL2/WHAMM/AP1AR/SLAIN2/C15orf62/WAS/TUBGCP5/CDH5/FMN1/ADD2/CHMP3/CKAP5/RAC3/TUBGCP3	94
BP	GO:0014037	Schwann cell differentiation	18/4749	37/18670	0.001953	0.02492	0.02027	EGR2/CDK1/NTRK2/GPC1/CDK5/SKI/FA2H/NAB2/NTRK3/MPP5/NDRG1/NAB1/ADAM22/POU3F1/SIRT2/DICER1/MED12/ILK	18
BP	GO:0035357	peroxisome proliferator activated receptor signaling pathway	12/4749	21/18670	0.001971	0.0251	0.02042	TWIST1/PPARG/PTGIS/ASXL2/FABP5/ACTN4/STARD10/ASXL1/RXRA/CITED2/FAM120B/SIRT1	12
BP	GO:0009205	purine ribonucleoside triphosphate metabolic process	109/4749	335/18670	0.001979	0.02515	0.02046	PPIF/CDK1/TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/COX8A/GPI/CBFA2T3/SIRT6/HK2/HSPA1A/NUP98/CTNS/SLC25A23/ENTPD5/ABCD1/DNAJC30/STAT3/TSPO/FXN/CCNB1/PGM2L1/PKM/AK5/ALDOC/VCP/OGDH/HTR2A/NDUFB11/COX6A1/PFKFB4/UQCRC1/SLC25A25/NUP153/FAM20C/AK3/NDUFB8/NME4/ATP1B1/BID/PINK1/DDIT4/NADK/ATP6V1A/VPS9D1/FIGNL1/GALK1/PFKFB2/NDUFS1/NUP88/ENO3/PRKAG2/NME3/NDUFS7/MYH7/PARK7/POM121C/NDUFB10/AK4/MYH4/NUP205/RAE1/MOCS1/NUP50/NDUFC1/IMPDH1/NDUFA9/COX4I1/UQCR11/RAB23/ALDOA/GUK1/AMPD3/IL4/ISCU/NDUFA12/AK1/INSR/NUPR1/SPHK2/NUP93/PFKL/NFS1/ALDOB/NUP35/NME9/AAAS/OLA1/TAZ/AK2/NDUFA4/MYH6/NDUFB2/TGFB1/NDUFA13/NMNAT1/NUP62/P2RX7/SEH1L/NCOR1/BAD/NME2	109
BP	GO:0032675	regulation of interleukin-6 production	55/4749	152/18670	0.002075	0.02632	0.02141	TWIST1/IL1B/KLF2/IL10/PTPN6/TLR8/IL17A/IL1RN/SIRPA/TIRAP/TNFSF4/CLEC7A/LGALS9/HMGB1/TNF/CD200/TLR4/LILRA2/FOXP3/CARD9/STAT3/ARHGEF2/ARRB1/HAVCR2/CD74/IRAK3/CD47/AIF1/TLR2/NOD2/LILRB2/GBA/IL27RA/C1QTNF3/TLR6/IL17RC/SYT11/CEBPB/CYBA/NLRC3/ZC3H12A/PAEP/RABGEF1/LILRA5/GHRL/RIPK2/F2R/MAPKAPK2/TYROBP/IL36A/AKIRIN2/TRAF6/PTAFR/P2RX7/IL37	55
BP	GO:0008156	negative regulation of DNA replication	19/4749	40/18670	0.002101	0.0266	0.02164	BCL6/CDC6/GMNN/SMC3/MSH6/BRCA2/HCRT/FBXO5/ZRANB3/TERF1/TIMELESS/S100A11/ZNF830/ATR/CHEK2/SMC1A/ATG7/TIPIN/TERF2	19
BP	GO:0006294	nucleotide-excision repair, preincision complex assembly	15/4749	29/18670	0.002133	0.02696	0.02193	DDB2/UBB/RPS27A/CDK7/RAD23B/UBA52/ERCC5/ERCC2/GTF2H2/GTF2H1/MNAT1/CETN2/GTF2H5/XPA/CUL4A	15
BP	GO:0016072	rRNA metabolic process	85/4749	253/18670	0.002161	0.0272	0.02213	GTF3C4/RPS8/RPL10A/RPS27/MTOR/RPL35/SMARCB1/USP36/NUDT16/XRN2/RPL5/RPL26/RPS6/RPS15/RRP1/MRPS11/PELO/RPL7/NSUN4/NOP10/ISG20/DDX27/NOL9/BYSL/POP5/GTF3C2/SMARCA4/RPS19/NSUN5P1/PA2G4/ERI3/FAM207A/RIOK1/RPS16/NCL/SART1/SBDS/RPS9/RPL14/NOLC1/YBEY/DDX17/ZNHIT3/NOP14/EXOSC2/TRMT112/NPM3/DDX54/UTP20/EMG1/BOP1/UTP23/BTRC/FBL/FDXACB1/DDX11/RRNAD1/METTL16/WDR12/ABT1/TEX10/RPS28/ZCCHC4/RPL7A/MRTO4/ESF1/GTF3C6/MDN1/URB1/RRP8/RPP30/RPL11/RPF1/GTF2H5/RCL1/UTP3/IPPK/SIRT7/TFB2M/DIS3L/POLR1B/NGDN/EXOSC9/SPIN1/SIRT1	85
BP	GO:1903321	negative regulation of protein modification by small protein conjugation or removal	35/4749	88/18670	0.002161	0.0272	0.02213	ISG15/CDK5/DNAJA1/HSPA1A/PIAS3/MTOR/SMAD7/TSPO/DTX3L/RPL5/FBXO5/ARRB1/CRY1/PER2/RPS3/N4BP1/UBXN1/RPL23/NXN/TRIM44/LIMK1/CHP1/PARK7/RASD2/USP44/PRKCE/HMG20A/BAG2/GCLC/MAD2L2/RPL11/HMG20B/GLMN/FYN/MAGEA2B	35
BP	GO:0031647	regulation of protein stability	94/4749	284/18670	0.002195	0.02753	0.0224	GTSE1/CDKN1A/AURKA/RASSF2/GAPDH/CTSH/TREX1/GRN/CTSA/HIP1/NF2/SIRT6/GSN/HSPA1A/DERL1/UBE2B/USP9X/PLK1/ZSWIM7/WNT10B/LMNA/SYVN1/ASPH/MSX1/SMAD7/PIM1/USP36/SRC/SEC16A/RPL5/PIM2/CLU/USP19/DVL3/KAT2A/PFN2/MYLIP/HTT/HIP1R/CCT5/DPM2/ISOC2/COG7/ATP1B1/HPS4/CDK7/RPL23/PINK1/MTMR9/CRYAA/STK3/USP40/DVL1/FLOT1/TAF9B/TRIM44/AAK1/MDM4/STX12/SUMO1/KDM8/NAA16/CHP1/PARK7/ATP1B3/PEX2/FBXW11/RAD23A/C10orf90/BAG3/CREBL2/BTRC/CDKN2AIP/BAG2/LAMP1/B4GALT5/PRNP/COG3/TYROBP/RNF139/TESC/CHEK2/GNAQ/ZBED3/NAPG/RPL11/PER3/WIZ/ID1/A1CF/MAPK1/FBXO4/CCT3/SIRT1	94
BP	GO:0051701	interaction with host	72/4749	209/18670	0.0022	0.02753	0.0224	CD86/ANPEP/CDK1/TYRO3/ITGA2/ICAM1/SLC1A5/IFIT1/CD80/GAPDH/MRC1/HAVCR1/TFRC/LGALS9/PML/TYMS/SMC3/CHMP2B/KPNA2/TNFRSF4/GSN/HSPA1A/TRIM25/LDLR/TRIM26/HYAL3/FCN1/SRC/IFITM2/TRIM62/SLC52A1/HTR2A/NTRK3/AXL/CD74/NUP153/CCR5/CTSB/CLEC4G/LGALS1/SLC52A2/FUCA2/TRIM13/SCRIB/IFITM3/IFITM1/THOC3/RXRA/CD46/MID2/CR2/KPNA3/CCNK/ZNF639/BCL2L1/IST1/ZC3H12A/UVRAG/RPSA/LAMP1/CLEC5A/DEFA1B/KRT6A/CHMP2A/INSR/TRIM35/ATG7/TGFB1/CHMP3/BAD/TRIM15/TRIM5	72
BP	GO:0001909	leukocyte mediated cytotoxicity	41/4749	107/18670	0.002201	0.02753	0.0224	CD1E/IL18/IL21/ICAM1/PTPN6/CTSH/CEACAM1/LGALS9/ULBP2/CD1A/RAET1E/CD1C/TUBB/RIPK3/HLA-H/HLA-G/SH2D1A/CD1B/HAVCR2/TUBB4B/HPRT1/CD1D/PTPRC/CORO1A/HLA-E/MICA/IL12RB1/ARG1/LAG3/CADM1/RAB27A/UNC13D/CRK/IL7R/LAMP1/ULBP1/TYROBP/KLRK1/P2RX7/PRDX1/IL23A	41
BP	GO:1903901	negative regulation of viral life cycle	34/4749	85/18670	0.002219	0.02766	0.0225	IFIT1/ISG15/APOBEC3H/PML/MX1/TNF/GSN/TRIM25/TRIM26/IFIT5/RSAD2/FCN1/IFITM2/BST2/MORC2/OASL/ISG20/TRIM13/BANF1/IFITM3/AICDA/IFITM1/MID2/CCNK/ZC3H12A/OAS1/IFI16/ILF3/ZC3HAV1/TRIM35/SETDB1/CHMP3/TRIM15/TRIM5	34
BP	GO:2001057	reactive nitrogen species metabolic process	34/4749	85/18670	0.002219	0.02766	0.0225	IL1B/ICAM1/KLF2/IL10/ACP5/SUOX/KLF4/RAC1/PTGIS/SIRPA/CLEC7A/TNF/TLR4/DDAH2/MTOR/TSPO/CLU/PKD2/NQO1/CD47/AIF1/TLR2/GCHFR/ATP2B4/TLR6/ZC3H12A/CD34/POR/HBB/INSR/SPR/KLRK1/CX3CR1/KHSRP	34
BP	GO:0006611	protein export from nucleus	63/4749	179/18670	0.002257	0.02808	0.02284	EGR2/IL1B/GTSE1/SEC13/U2AF1/CAMK1/CDK5/YWHAE/RBM22/NUP98/SMG5/POLDIP3/PTPN14/CSE1L/IWS1/SFN/HSPA9/RNPS1/RPS15/ENY2/SRSF4/NUP153/UPF1/MAGOHB/SMURF1/TCF7L2/DUSP16/ABCE1/STRADB/ALKBH5/SUPT6H/XPO6/NUP88/THOC3/CHP1/PARK7/EMD/U2AF1L4/POM121C/NUP205/RAE1/NUP50/BAG3/DHX38/SDAD1/MAGOH/CPSF1/UHMK1/SMG6/GLE1/NUP93/DDX19A/CDC40/NUP35/AAAS/NCBP2/TGFB1/CCHCR1/NUP62/SEH1L/YTHDC1/BARD1/NXF3	63
BP	GO:0046034	ATP metabolic process	100/4749	305/18670	0.002268	0.02816	0.02291	PPIF/CDK1/TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/COX8A/GPI/CBFA2T3/SIRT6/HK2/HSPA1A/NUP98/CTNS/SLC25A23/ENTPD5/ABCD1/DNAJC30/STAT3/TSPO/FXN/CCNB1/PGM2L1/PKM/AK5/ALDOC/VCP/OGDH/HTR2A/NDUFB11/COX6A1/PFKFB4/UQCRC1/SLC25A25/NUP153/FAM20C/NDUFB8/ATP1B1/BID/PINK1/DDIT4/NADK/ATP6V1A/VPS9D1/FIGNL1/GALK1/PFKFB2/NDUFS1/NUP88/ENO3/PRKAG2/NDUFS7/MYH7/PARK7/POM121C/NDUFB10/AK4/MYH4/NUP205/RAE1/NUP50/NDUFC1/NDUFA9/COX4I1/UQCR11/ALDOA/GUK1/AMPD3/IL4/ISCU/NDUFA12/AK1/INSR/NUPR1/SPHK2/NUP93/PFKL/ALDOB/NUP35/AAAS/OLA1/TAZ/AK2/NDUFA4/MYH6/NDUFB2/TGFB1/NDUFA13/NMNAT1/NUP62/P2RX7/SEH1L/NCOR1/BAD	100
BP	GO:0046209	nitric oxide metabolic process	33/4749	82/18670	0.002274	0.02817	0.02292	IL1B/ICAM1/KLF2/IL10/ACP5/KLF4/RAC1/PTGIS/SIRPA/CLEC7A/TNF/TLR4/DDAH2/MTOR/TSPO/CLU/PKD2/NQO1/CD47/AIF1/TLR2/GCHFR/ATP2B4/TLR6/ZC3H12A/CD34/POR/HBB/INSR/SPR/KLRK1/CX3CR1/KHSRP	33
BP	GO:0034612	response to tumor necrosis factor	102/4749	312/18670	0.002287	0.02828	0.02301	SGMS1/ICAM1/KLF2/TXNDC17/CCL20/CCL3L3/TNFRSF18/CCL22/TNFSF4/RFFL/GBP2/UBD/EDARADD/TNFRSF12A/TNF/ZFP36/TNFRSF4/HSPA1A/TNFRSF8/NOL3/PIAS3/TNFRSF21/BAG4/HYAL3/GGT1/TRAIP/ARHGEF2/PSMD8/CLIP3/CCL3/PSMD1/PSMD2/LIMS1/KAT2A/RPS3/SLC2A4/PSMF1/CCL2/ZFP36L2/TNFRSF19/CCL17/MAP3K5/CYLD/TNFRSF9/ADAMTS13/CCL18/ACTN4/CXCL16/CD58/PSMD9/TANK/GBA/PSMA5/TNFRSF13B/LTA/PSMB7/TNFSF12/NFKBIA/TRAF1/PSMD5/TNFSF9/CYBA/ZC3H12A/BIRC3/PSME2/SFRP1/TRAF2/PIAS4/ST18/TNFSF13/ADIPOQ/TNFRSF11B/PSMB5/TNFRSF1B/ZFP36L1/PSMB4/CCL23/PSMA3/STAT1/CARD8/TNFSF11/EDAR/CCL7/GSS/ZNF675/PSMD10/CCL15/PSMB1/PSMD7/HAS2/COMMD7/PSMB3/SPATA2/MAPK1/ADAM9/PSMC5/GATA3/ILK/TNFRSF25/PSMD11/ZFAND6/SIRT1	102
BP	GO:0097305	response to alcohol	79/4749	233/18670	0.002291	0.02828	0.02301	CDK1/CDKN1A/PPARG/ICAM1/FOSL1/KLF2/KLF4/SPI1/TNFSF4/GLB1/PTCH1/FOSB/TYMS/EIF4EBP1/SETD7/LRP8/GSN/CYBB/RPL10A/GRAMD1C/RAD51/LANCL2/STAT3/PMVK/ABAT/GGH/CCL3/PTGER4/NTRK3/ADCY6/CCR5/SLC2A4/NQO1/KCNMB1/GRAMD1B/RGS19/KLF9/OXCT1/ABCA1/BAK1/RECQL5/TP53INP1/CNR1/PRKCE/PTGER2/ADCY3/RPS4X/BCL2L1/CYBA/ADAM15/TBXA2R/CTNNA1/IL13/BGLAP/SFRP1/HSD3B2/S100A8/ADIPOQ/MAP4K1/AANAT/LRP6/OSBPL7/SPHK2/HPGD/NEFL/CCL7/GRAMD1A/FOS/OGG1/CYP7A1/TGFB1/MGMT/RARA/CCND1/SETDB1/TUFM/GATA3/BAD/FYN	79
BP	GO:0009615	response to virus	106/4749	326/18670	0.002316	0.02844	0.02313	IL1B/MAPK11/IRF7/NLRP3/FOSL1/IFIT1/TSPAN32/BNIP3L/ISG15/BCL3/TLR8/TREX1/CCL22/TNFSF4/OAS2/ENO1/LGALS9/APOBEC3H/UNC93B1/PML/SERINC3/MX1/PQBP1/TNF/IRF5/IL2RA/CXCL10/TRIM25/PMAIP1/FOXP3/IFIT5/MMP12/CARD9/APOBEC3B/HYAL3/RSAD2/SRC/IFITM2/IFI6/DTX3L/SEC14L1/CD207/PIM2/CLU/BST2/IFIT3/OASL/URI1/CREBZF/RPS15A/IRAK3/TRIM22/NPLOC4/CCT5/ISG20/POLR3H/PTPRC/ABCE1/DDIT4/STMN1/CFL1/CXCL9/AP1S1/TRIM44/MICA/BANF1/IL12RB1/IFITM3/AICDA/IFITM1/RNF216/UNC13D/FMR1/GBF1/DDX17/LGALS8/RNASE6/BCL2L1/IRF3/ZC3H12A/SAMHD1/BIRC3/OAS1/CNOT7/IFI16/IFNGR1/ILF3/ZC3HAV1/DEFA1B/C1QBP/IFIT2/CRCP/TSPAN6/STAT1/ACTA2/HTRA1/ANKRD17/ATG7/CCDC130/ZCCHC3/GATA3/USP17L2/BAD/TRIM15/IL23A/TRIM5	106
BP	GO:0002437	inflammatory response to antigenic stimulus	21/4749	46/18670	0.002319	0.02844	0.02313	NOTCH1/ICAM1/CD68/IL10/TREX1/HMGB1/TNF/IL2RA/GPX1/BTK/CYSLTR1/RBPJ/HLA-E/LTA/CNR1/PARK7/IL5RA/CD6/PSMB4/NPFF/GATA3	21
BP	GO:0006221	pyrimidine nucleotide biosynthetic process	21/4749	46/18670	0.002319	0.02844	0.02313	TYMS/DHODH/AGPAT3/AGPAT2/CMPK2/ERH/DTYMK/AK5/NME4/UPRT/DCTD/NME3/TAMM41/LCLAT1/CMPK1/CTPS2/UCK2/PRPS1/NME9/GPAT2/NME2	21
BP	GO:1900034	regulation of cellular response to heat	32/4749	79/18670	0.002325	0.02844	0.02313	SEC13/YWHAE/HSPA1A/NUP98/MTOR/BAG4/CAMK2A/NUP153/CHORDC1/NUP88/CAMK2G/POM121C/NUP205/RAE1/NUP50/BAG3/BAG2/DNAJB6/CAMK2D/CD34/MAPKAPK2/HSPA1L/ATR/NUP93/NUP35/ATM/AAAS/MAPK1/NUP62/SEH1L/MLST8/SIRT1	32
BP	GO:0032147	activation of protein kinase activity	108/4749	333/18670	0.002326	0.02844	0.02313	IQGAP3/IL1B/TPX2/MAPK11/KIF14/VEGFA/IL18/TP73/CDK1/WNK1/GADD45G/FPR1/NTRK1/DUSP6/CLSPN/TIRAP/TNF/ADRA2B/TLR4/PTPN1/GADD45A/PEA15/MTOR/TRAF7/ADCY4/RIPK3/SRC/MAP3K6/MAP2K3/DUSP5/DBF4B/MAPKAP1/ARRB1/PAK4/MAP3K2/NTRK3/UBB/TGFB3/CD74/PAK1/ADCY6/UBE2N/MAP2K6/PPP2R3C/RPS27A/PAK3/TNFRSF10B/MAP3K5/PINK1/FGF13/PTPRC/STRADB/STK3/ITGA1/NRK/UBA52/NOD2/TRAF4/MAP3K11/IRAK1/TAOK3/PRKAG2/TLR6/RAPGEF1/PARK7/STK25/PRRC1/ACVR2B/TAB1/CRK/PIBF1/ECT2/ADCY3/MAP3K3/MINK1/NEK1/MAP2K4/TRAF2/GHRL/IL4/MAP4K1/ERN1/PRNP/RIPK2/F2R/MAPKAPK2/CHRNA3/PRKACB/LAMTOR2/INSR/TRAF6/ADCY9/BIRC7/TNFSF11/NTF3/MAP3K9/TOM1L1/SHC2/ADNP/MAPK1/ADAM9/PDGFB/P2RX7/SHC1/MLST8/PAK2/IL23A/AVPI1	108
BP	GO:1903426	regulation of reactive oxygen species biosynthetic process	39/4749	101/18670	0.002367	0.02884	0.02346	IL1B/ICAM1/KLF2/IL10/ACP5/KLF4/RAC1/PTGIS/SIRPA/CLEC7A/TNF/TLR4/DDAH2/CTNS/MTOR/ABCD1/STAT3/TSPO/ABCD2/CFLAR/CLU/PKD2/CD47/AIF1/ATP2B4/RAB27A/TLR6/PARK7/ZNF205/CYBA/ZC3H12A/CD34/HBB/INSR/SPHK2/KLRK1/CX3CR1/KHSRP/FYN	39
BP	GO:0016236	macroautophagy	97/4749	295/18670	0.002368	0.02884	0.02346	SQSTM1/GPSM1/BNIP3L/GAPDH/ATP6V0D1/TP53INP2/LZTS1/CDK5/TEX264/MTMR3/CHMP2B/MAP1LC3A/ATP6V0B/UBXN6/MTOR/CAPN1/NBR1/SNF8/USP36/SRC/HMOX1/ATG9A/VCP/PIM2/ATP13A2/STAM/ATP6V1E1/SNAP29/KLHL3/HTT/FYCO1/AMBRA1/ATP6V0C/PIKFYVE/CALCOCO2/SMURF1/PRKAB2/PINK1/QSOX1/ATP6V1A/TRIM13/ULK1/TOMM6/GBA/TP53INP1/HGS/STX12/PRKAG2/VDAC1/SLC38A9/LGALS8/ATG2B/KIAA1324/BAG3/UVRAG/MTMR14/LACRT/SNAPIN/ATP6V1G1/UBQLN2/NPRL3/RAB23/PIK3C3/IL4/ERN1/RIPK2/ATG4B/NSFL1C/TMEM41B/LRSAM1/LAMTOR4/WDR45/CHMP2A/LAMTOR2/NUPR1/PIP4K2A/PIK3R4/RAB1A/ATP6V1E2/VPS13D/TOMM22/RALB/PIP4K2B/RRAGB/PHF23/ATG7/PGAM5/UCHL1/HDAC10/SESN2/MLST8/CHMP3/RAB1B/FUNDC1/RAB12/SIRT1/NPRL2	97
BP	GO:0010508	positive regulation of autophagy	44/4749	117/18670	0.002381	0.02893	0.02353	GPSM1/BNIP3L/TP53INP2/HMGB1/HK2/PLK2/HMOX1/PIM2/HTT/FYCO1/AMBRA1/TRIM22/CALCOCO2/FOXO1/SMURF1/TPCN1/PINK1/TRIM13/ULK1/GBA/TP53INP1/MID2/PARK7/SH3BP4/KIAA1324/TFEB/ZC3H12A/BAG3/UVRAG/LACRT/GSK3A/DAPK1/IL4/RIPK2/LRSAM1/PIP4K2A/VPS13D/RALB/PIP4K2B/SESN2/BAD/RAB12/SIRT1/NPRL2	44
BP	GO:0001913	T cell mediated cytotoxicity	22/4749	49/18670	0.002393	0.02893	0.02353	CD1E/CTSH/CEACAM1/ULBP2/CD1A/RAET1E/CD1C/RIPK3/HLA-H/HLA-G/CD1B/HPRT1/CD1D/PTPRC/HLA-E/MICA/IL12RB1/RAB27A/IL7R/ULBP1/P2RX7/IL23A	22
BP	GO:0051205	protein insertion into membrane	22/4749	49/18670	0.002393	0.02893	0.02353	TP73/YWHAH/YWHAE/TP63/YWHAZ/E2F1/BAX/PMAIP1/MOAP1/SFN/BMF/COX18/NMT1/SGTA/BID/TRAM2/TFDP2/YWHAQ/GRIN3B/BAD/REEP1/UBL4A	22
BP	GO:0071349	cellular response to interleukin-12	22/4749	49/18670	0.002393	0.02893	0.02353	LMNB1/IL10/SIRPA/ANXA2/PITPNA/PDCD4/HSPA9/IL12RB2/GSTO1/CD47/CFL1/IL12RB1/RALA/CAPZA1/STAT4/MTAP/PSME2/CNN2/PLCB1/CDC42/PAK2/JAK1	22
BP	GO:0006997	nucleus organization	48/4749	130/18670	0.002412	0.02908	0.02366	CDK1/DYRK3/CCNB2/PPP2R1A/PML/SERBP1/REEP3/CHMP2B/NUP98/PLK1/TMEM43/LMNA/USP36/CCNB1/NUMA1/REEP4/NUP153/SUN2/RPS19/PRKCA/LEMD3/PPP2CA/BANF1/SPAG4/RNF8/NOLC1/SUMO1/EMD/WDR73/TMEM170A/PARP11/NUP205/EMG1/WRAP53/CHMP1A/NSFL1C/DMRTC2/SUMO1P1/PRKCB/PYGO1/CHMP2A/NUP93/NUP35/NEK9/TMF1/POLR1B/SEH1L/LPIN1	48
BP	GO:2001234	negative regulation of apoptotic signaling pathway	78/4749	230/18670	0.002415	0.02908	0.02366	PPIF/IL1B/CSF2/ICAM1/FAIM2/PLAUR/ZNF385A/RFFL/MCL1/ENO1/DNAJA1/LGALS3/PRELID1/MMP9/TNF/HSPA1A/RRM2B/CTTN/NOL3/BAX/PTPN1/SERPINE1/PEA15/GPX1/LMNA/SYVN1/FXN/SRC/IFI6/SNAI1/HMOX1/ARHGEF2/CFLAR/CLU/CD74/URI1/HERPUD1/HTT/CTH/EYA2/PHIP/FAS/TCF7L2/BID/TNFRSF10B/PINK1/STRADB/ITGA6/FIGNL1/BCL2A1/TAF9B/MUC1/MEIS3/BDKRB2/GNAI2/PARK7/BCL2L12/SLC25A5/CD44/TXNDC12/BCL2L1/YAP1/IL7/SIAH2/CTNNA1/ASAH2/TRAF2/TNFSF10/FZD9/GCLC/PAM16/VNN1/PSMD10/NDUFA13/PDX1/CX3CR1/FYN/SIRT1	78
BP	GO:0044090	positive regulation of vacuole organization	9/4749	14/18670	0.002446	0.02924	0.02379	GRN/ANXA2P2/ANXA2/ULK1/KIAA1324/LRSAM1/PIP4K2A/RALB/PIP4K2B	9
BP	GO:0016447	somatic recombination of immunoglobulin gene segments	23/4749	52/18670	0.002446	0.02924	0.02379	IL10/BATF/EXO1/BCL6/TNFSF4/TFRC/MSH6/FOXP3/SWAP70/CCR6/TP53BP1/PTPRC/SUPT6H/AICDA/IL27RA/RNF8/APLF/TNFSF13/IL4/MAD2L2/TGFB1/ERCC1/RNF168	23
BP	GO:0045839	negative regulation of mitotic nuclear division	23/4749	52/18670	0.002446	0.02924	0.02379	CENPF/AURKB/BUB1B/TTK/CDT1/TRIP13/CDC20/PTTG1/BUB1/PLK1/CCNB1/FBXO5/NDC80/TOM1L2/CHEK1/USP44/XRCC3/MAD2L2/KLHL22/APC/ATM/TOM1L1/DUSP1	23
BP	GO:0051235	maintenance of location	107/4749	330/18670	0.002451	0.02924	0.02379	IL1B/GPSM2/ASPM/PPARG/IL10/ABCG1/PTPN6/BCL3/HK1/CDK5/CHERP/PML/HSPA5/TNF/HK2/GSN/GM2A/NFKBIE/JSRP1/NOL3/BAX/CXCL10/TRPC1/SLC25A23/DAND5/FFAR2/TSPO/SORL1/MYO5A/FITM2/TONSL/PDE4D/KDELR2/HTR2A/ATP2A1/CCL3/FITM1/SRI/CRY1/PKD2/CCR5/SUN2/HTT/GSTO1/TMSB4Y/TPCN1/PINK1/PTPRC/EZR/CORO1A/RASA3/ANXA5/TWF2/CXCL9/ABCA1/AP3D1/INSIG1/DRD1/SPAG4/FKBP1A/DDIT3/THY1/CD19/FTL/NTSR1/PARK7/ACVR1C/TOPORS/MEST/NFKBIA/PRKCE/FTH1/PLIN2/NFKBIL1/SRGN/CYBA/ZC3H12A/UVRAG/SQLE/LACRT/SYNE3/IL13/TMSB15A/S100A8/CAMK2D/BSCL2/ARL2BP/F2R/DGAT2/GOPC/POLR2M/ACACB/HEXB/VPS13D/TTC39B/ARL2/PPARD/CER1/PSMD10/PLCB1/TGFB1/MXI1/SYNE2/P2RX7/SREBF2/BARD1/SIRT1	107
BP	GO:0031341	regulation of cell killing	38/4749	98/18670	0.002451	0.02924	0.02379	CD1E/IL21/ICAM1/GAPDH/CLEC7A/CEACAM1/LGALS9/ULBP2/CD1A/RAET1E/CD1C/RIPK3/HLA-H/HLA-G/SH2D1A/CD1B/HAVCR2/CD1D/PGLYRP3/PTPRC/HLA-E/MICA/IL12RB1/ARG1/LAG3/CADM1/CRK/IL7R/IL13/LAMP1/IL4/ULBP1/TYROBP/KRT6A/KLRK1/P2RX7/BAD/IL23A	38
BP	GO:0032102	negative regulation of response to external stimulus	117/4749	365/18670	0.00247	0.02941	0.02392	CXCL13/PBK/CD109/NOTCH1/TYRO3/CDKN1A/PPARG/NLRP3/DUSP10/ADORA2A/IL10/TRIB1/KANK2/ACP5/KLF4/PDGFA/PLAUR/GRN/PTGIS/SIRPA/ANXA2P2/BBS2/CEACAM1/SPP1/CD9/SEMA4C/SEMA7A/PROS1/IL2RA/CD200/TMPRSS6/PROC/PLAU/LILRA2/SERPINE1/FOXP3/ADTRP/RGMA/ANXA2/LDLR/GPX1/ABCD1/IL1R2/SEMA3G/PDCD4/PLAT/SOCS3/SEC14L1/ABCD2/ABAT/SEMA6C/CORO1B/NENF/PTGER4/HAVCR2/SEMA6B/CCL2/NPLOC4/C5orf30/CCK/PTPRC/SIGIRR/RPS19/CLASP2/AIF1/ANXA5/DVL1/VTN/MKKS/DRD1/GBA/C1QTNF3/FPR2/CRK/DEFB114/NFKBIL1/SEMA3B/NLRC3/ZC3H12A/KLKB1/RABGEF1/LACRT/SEMA5B/SERPING1/PADI2/NUCB2/SIRT2/MMP26/GHRL/CHID1/ADIPOQ/IL4/CD34/TNFRSF1B/PTPRS/NT5E/PSMB4/SEMA4D/C1QBP/SIGLEC10/BCR/TSPAN6/CARD8/NPFF/PPARD/HTRA1/DDT/METRNL/SEMA5A/SIGLEC11/RTN4R/CDH5/KLRK1/PDGFB/GATA3/TFPI/DUSP1	117
BP	GO:0032640	tumor necrosis factor production	58/4749	163/18670	0.002484	0.02952	0.02402	TWIST1/IL10/ACP5/PTPN6/BCL3/TREX1/SIRPA/TIRAP/CLEC7A/GPNMB/LGALS9/HMGB1/ZFP36/TNFRSF8/CYBB/TLR4/LILRA2/FOXP3/CARD9/TSPO/CCR2/ARHGEF2/CCL3/CLU/HAVCR2/AXL/CD33/IRAK3/PTPRC/HLA-E/CD47/TLR2/NOD2/IL27RA/DEFB114/SYT11/AZI2/NFKBIL1/CYBA/NLRC3/ZC3H12A/LILRA5/IFNGR1/GHRL/ADIPOQ/IL4/CD34/RIPK2/MAPKAPK2/TYROBP/DICER1/SPHK2/FZD5/DDT/RARA/PTAFR/CX3CR1/IL23A	58
BP	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	26/4749	61/18670	0.002504	0.0297	0.02417	SKIL/MCL1/SFPQ/SERINC3/BAX/PMAIP1/PLAGL2/MSX1/RIPK3/RPL26/BMF/UBB/RPS3/BID/BCAP31/DDIT3/STYXL1/PARK7/BCL2L1/PIAS4/S100A8/NUPR1/RPL11/BAD/RAD9A/SIRT1	26
BP	GO:0006914	autophagy	154/4749	496/18670	0.002518	0.02976	0.02421	SQSTM1/GPSM1/IL10/BNIP3L/GAPDH/ATP6V0D1/TP53INP2/CTSA/LZTS1/DAPK2/MCL1/CDK5/TEX264/MTMR3/CHMP2B/HMGB1/HK2/TM9SF1/PLK2/CTTN/MAP1LC3A/ATP6V0B/UBXN6/MTOR/CAPN1/TMEM150C/NBR1/STAT3/SNF8/TSPO/DAP/USP36/SRC/HMOX1/ATG9A/VCP/PIM2/BMF/ATP13A2/CLU/STAM/ATP6V1E1/SNAP29/KLHL3/HTT/TMEM150A/FYCO1/AMBRA1/ATP6V0C/PIKFYVE/TRIM22/CALCOCO2/FOXO1/TOLLIP/SBF2/SMURF1/TPCN1/PRKAB2/PINK1/WDR24/MTMR9/QSOX1/NAMPT/RGS19/ATP6V1A/VPS51/TRIM13/ULK1/TOMM6/GBA/TP53INP1/DDIT3/HGS/STX12/PLEKHM1/PRKAG2/EEF1A1/MID2/VDAC1/SLC38A9/PARK7/SH3BP4/MAP1S/LGALS8/ATG2B/KIAA1324/ACER2/TFEB/ZC3H12A/EEF1A2/BAG3/UVRAG/MTMR14/LACRT/GSK3A/SNAPIN/IFI16/ATP6V1G1/UBQLN2/DAPK1/RAB39B/NPRL3/RAB23/PIK3C3/SIRT2/S100A8/IL4/ERN1/RIPK2/ATG4B/NSFL1C/TMEM41B/LRSAM1/LAMTOR4/WDR45/CHMP2A/LAMTOR2/NUPR1/KLHL22/OSBPL7/PIP4K2A/PIK3R4/FUNDC2/TMEM150B/RAB1A/ATP6V1E2/VPS13D/IL10RA/TOMM22/RALB/XPA/FZD5/PIP4K2B/VPS39/ATM/RRAGB/PHF23/ATG7/PGAM5/UCHL1/HDAC10/DRAM1/SESN2/MLST8/SREBF2/CHMP3/BAD/RAB1B/TRIB3/FUNDC1/RAB12/SIRT1/NPRL2/TRIM5	154
BP	GO:0061919	process utilizing autophagic mechanism	154/4749	496/18670	0.002518	0.02976	0.02421	SQSTM1/GPSM1/IL10/BNIP3L/GAPDH/ATP6V0D1/TP53INP2/CTSA/LZTS1/DAPK2/MCL1/CDK5/TEX264/MTMR3/CHMP2B/HMGB1/HK2/TM9SF1/PLK2/CTTN/MAP1LC3A/ATP6V0B/UBXN6/MTOR/CAPN1/TMEM150C/NBR1/STAT3/SNF8/TSPO/DAP/USP36/SRC/HMOX1/ATG9A/VCP/PIM2/BMF/ATP13A2/CLU/STAM/ATP6V1E1/SNAP29/KLHL3/HTT/TMEM150A/FYCO1/AMBRA1/ATP6V0C/PIKFYVE/TRIM22/CALCOCO2/FOXO1/TOLLIP/SBF2/SMURF1/TPCN1/PRKAB2/PINK1/WDR24/MTMR9/QSOX1/NAMPT/RGS19/ATP6V1A/VPS51/TRIM13/ULK1/TOMM6/GBA/TP53INP1/DDIT3/HGS/STX12/PLEKHM1/PRKAG2/EEF1A1/MID2/VDAC1/SLC38A9/PARK7/SH3BP4/MAP1S/LGALS8/ATG2B/KIAA1324/ACER2/TFEB/ZC3H12A/EEF1A2/BAG3/UVRAG/MTMR14/LACRT/GSK3A/SNAPIN/IFI16/ATP6V1G1/UBQLN2/DAPK1/RAB39B/NPRL3/RAB23/PIK3C3/SIRT2/S100A8/IL4/ERN1/RIPK2/ATG4B/NSFL1C/TMEM41B/LRSAM1/LAMTOR4/WDR45/CHMP2A/LAMTOR2/NUPR1/KLHL22/OSBPL7/PIP4K2A/PIK3R4/FUNDC2/TMEM150B/RAB1A/ATP6V1E2/VPS13D/IL10RA/TOMM22/RALB/XPA/FZD5/PIP4K2B/VPS39/ATM/RRAGB/PHF23/ATG7/PGAM5/UCHL1/HDAC10/DRAM1/SESN2/MLST8/SREBF2/CHMP3/BAD/RAB1B/TRIB3/FUNDC1/RAB12/SIRT1/NPRL2/TRIM5	154
BP	GO:0031668	cellular response to extracellular stimulus	89/4749	268/18670	0.002535	0.02991	0.02433	VDR/CDKN1A/PPARG/GAS2L1/ICAM1/FOSL1/CD68/KANK2/CDKN2B/FES/SRF/BCL11A/DCTPP1/DSC2/MTMR3/ATF3/HSPA5/CYBB/MAP1LC3A/PMAIP1/MTOR/GDAP1/ITFG2/PIM1/DAP/NUDT1/HMOX1/P2RY11/AMIGO1/PDXP/AXL/USF2/ATF4/NMRAL1/NUAK2/ASNS/PHEX/AMBRA1/ARHGAP35/FOXO1/CASR/AQP2/FAS/PICK1/MAP3K5/WDR24/NAMPT/PTPRC/TRPM4/C12orf66/AIF1/ITGA6/ULK1/GBA/JUN/SLC38A2/CYP27B1/MYBBP1A/KIAA1324/CYBA/ZC3H12A/KLF10/IFI16/KRT20/BGLAP/NPRL3/SFRP1/PIK3C3/EIF2AK3/WDR45/P2RY1/MAX/RRP8/PIK3R4/RALB/PPP1R9B/FOS/RRAGB/WRN/ATG7/ADNP/MAPK1/SESN2/P2RX7/SEH1L/SREBF2/FYN/SIRT1/NPRL2	89
BP	GO:0036294	cellular response to decreased oxygen levels	74/4749	217/18670	0.002609	0.03072	0.02499	EGR1/TWIST1/VEGFA/NOTCH1/ICAM1/BNIP3L/CCNA2/PTGIS/ENO1/EIF4EBP1/E2F1/CYBB/NOL3/PMAIP1/MTOR/LMNA/CCNB1/SRC/HMOX1/LIMD1/PSMD8/CFLAR/USP19/UBB/PSMD1/PSMD2/RBPJ/ATF4/SLC2A4/PSMF1/RPS27A/CASR/KCNMB1/PICK1/PINK1/NAMPT/NDRG1/UBA52/PSMD9/IRAK1/PSMA5/VASN/MDM4/PSMB7/HIF3A/PRKCE/AK4/EPAS1/PSMD5/CITED2/PSME2/SFRP1/SIRT2/PSMB5/CD34/ZFP36L1/CPEB1/PSMB4/MALAT1/PSMA3/HIF1AN/BACH1/PPARD/CLCA1/PSMD10/PSMB1/PSMD7/PSMB3/KCNK2/PSMC5/BAD/MGARP/PSMD11/SIRT1	74
BP	GO:0035710	CD4-positive, alpha-beta T cell activation	36/4749	92/18670	0.00262	0.03079	0.02505	CD86/IL18/RELB/NLRP3/BATF/CD83/CD80/IRF4/BCL3/BCL6/CBFB/TNFSF4/LGALS9/HMGB1/MTOR/FOXP3/STAT3/IL4R/RSAD2/SMAD7/PTGER4/LY9/HLX/SATB1/RORC/IL12RB1/IL18R1/CDH26/ZC3H12A/RIPK2/PAX1/JAK3/RARA/ZFPM1/GATA3/IL23A	36
BP	GO:0030705	cytoskeleton-dependent intracellular transport	63/4749	180/18670	0.002624	0.03079	0.02505	KIF4A/MAP6/KIF23/KIF1C/TUBA1B/SFPQ/TUBA1C/TTC30A/UXT/WDR34/TUBB/MYO5A/BLOC1S6/DYNLRB1/BLOC1S1/UBB/ICK/CNIH2/KLC3/SUN2/HTT/FYCO1/BLOC1S4/IFT122/ACTN4/AP3D1/IFT172/TTC21A/DTNBP1/KIF3C/HOOK2/FMR1/IFT27/MAP1S/WDR60/BBS12/WDR19/BAG3/AP3M2/SNAPIN/CCDC88B/LAMP1/IFT80/LRPPRC/ACTR1A/RHOT2/MAP1A/RAB1A/NEFL/ARL3/TMEM201/TTC26/AP3B2/COPG2/CDC42/CLUAP1/UCHL1/SPG7/SYNE2/TNPO1/SYBU/MGARP/TERF2	63
BP	GO:0043406	positive regulation of MAP kinase activity	86/4749	258/18670	0.002631	0.03081	0.02506	IQGAP3/IL1B/MAPK11/VEGFA/TP73/CDK1/GADD45G/FPR1/NTRK1/PDGFA/DUSP6/TNF/ADRA2B/FGD2/TLR4/PTPN1/GADD45A/PEA15/TRAF7/SRC/TENM1/MAP3K6/ARHGEF5/TIAM1/MAP2K3/DUSP5/ARRB1/HTR2A/MAP3K2/NTRK3/DVL3/UBB/TGFB3/CD74/PAK1/UBE2N/RPS3/MAP2K6/PIK3R5/FLT3/RPS27A/PAK3/MAP3K5/PTPRC/ITGA1/EZH2/NRK/UBA52/NOD2/MAP3K11/IRAK1/FLT1/TAOK3/TLR6/FZD8/RAPGEF1/ERBB2/TAB1/CRK/MAP3K3/MAP2K4/TRAF2/GHRL/MAP4K1/ERN1/RIPK2/F2R/MAPKAPK2/LAMTOR2/INSR/TRAF6/BIRC7/AKAP13/TNFSF11/FZD5/NTF3/MAP3K9/TGFB1/SHC2/MAPK1/ADAM9/PDGFB/P2RX7/SHC1/ILK/AVPI1	86
BP	GO:0045622	regulation of T-helper cell differentiation	17/4749	35/18670	0.002644	0.03081	0.02506	CD86/IL18/NLRP3/CD80/IRF4/BCL6/TNFSF4/FOXP3/IL4R/SMAD7/HLX/IL12RB1/ZC3H12A/RIPK2/JAK3/RARA/IL23A	17
BP	GO:0002726	positive regulation of T cell cytokine production	11/4749	19/18670	0.002645	0.03081	0.02506	IL1B/IL18/NLRP3/IL1R1/TNFSF4/RSAD2/IL18R1/TRAF2/TRAF6/FZD5/GATA3	11
BP	GO:0046641	positive regulation of alpha-beta T cell proliferation	11/4749	19/18670	0.002645	0.03081	0.02506	EBI3/IL18/TNFSF4/LGALS9/CCR2/PTPRC/HLA-E/CD3E/RIPK2/ZAP70/IL23A	11
BP	GO:0071456	cellular response to hypoxia	71/4749	207/18670	0.002664	0.03097	0.0252	EGR1/TWIST1/VEGFA/NOTCH1/ICAM1/BNIP3L/CCNA2/PTGIS/ENO1/EIF4EBP1/E2F1/CYBB/NOL3/PMAIP1/MTOR/LMNA/CCNB1/SRC/HMOX1/LIMD1/PSMD8/CFLAR/USP19/UBB/PSMD1/PSMD2/RBPJ/SLC2A4/PSMF1/RPS27A/CASR/KCNMB1/PINK1/NDRG1/UBA52/PSMD9/IRAK1/PSMA5/VASN/MDM4/PSMB7/HIF3A/PRKCE/AK4/EPAS1/PSMD5/CITED2/PSME2/SFRP1/SIRT2/PSMB5/CD34/ZFP36L1/CPEB1/PSMB4/MALAT1/PSMA3/HIF1AN/BACH1/PPARD/CLCA1/PSMD10/PSMB1/PSMD7/PSMB3/KCNK2/PSMC5/BAD/MGARP/PSMD11/SIRT1	71
BP	GO:0097191	extrinsic apoptotic signaling pathway	76/4749	224/18670	0.002683	0.03114	0.02534	G0S2/SKIL/IL1B/CSF2/ICAM1/CASP9/FAIM2/MLLT11/RFFL/MCL1/LGALS3/ATF3/PPP2R1A/PML/TNFRSF12A/TNF/HSPA1A/CTTN/NOL3/BAX/SERPINE1/PEA15/PMAIP1/GPX1/LMNA/SRC/IFI6/MOAP1/HMOX1/PARP2/ARHGEF2/TMC8/CFLAR/HTT/SGPP1/EYA2/PHIP/FAS/TCF7L2/BID/TNFRSF10B/PTPRC/CYLD/STRADB/STK3/ITGA6/BCL2A1/BAK1/FEM1B/WWOX/CASP8AP2/PARK7/TNFSF12/TRAF1/DEPTOR/BCL2L1/YAP1/BAG3/IL7/SIAH2/CTNNA1/GSK3A/DAPK1/SFRP1/TRAF2/TNFRSF1B/TNFSF10/GCLC/ITM2C/TIMP3/TGFB1/NDUFA13/P2RX7/BAD/FYN/PAK2	76
BP	GO:0046434	organophosphate catabolic process	83/4749	248/18670	0.002725	0.03156	0.02568	TPI1/DCTPP1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/PDE4A/GPI/CBFA2T3/SIRT6/HK2/ABHD16A/NUP98/ENTPD5/LDLR/GPX1/ABCD1/CNP/STAT3/GDPD3/NUDT16/NUDT1/PGM2L1/PKM/PDE4D/ALDOC/VCP/OGDH/HTR2A/PDXP/PDE4B/PFKFB4/HPRT1/ENTPD2/NUP153/GDPD1/PNP/IMPA2/DDIT4/GALK1/PFKFB2/NUP88/ENO3/PRKAG2/NTSR1/POM121C/NUP205/INPP1/RAE1/NUDT17/NUP50/SAMHD1/PLA2G15/PNPLA6/ENTPD4/NUDT3/PRDX6/ALDOA/AMPD3/GDE1/NT5E/PDE7B/INSR/NUPR1/NUP93/NEIL1/PFKL/ALDOB/NUP35/OGG1/AAAS/GPCPD1/NT5C2/NUP62/P2RX7/SEH1L/NCOR1/ASPDH	83
BP	GO:0009201	ribonucleoside triphosphate biosynthetic process	62/4749	177/18670	0.002762	0.03194	0.02598	TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/GPI/CBFA2T3/SIRT6/HK2/NUP98/ENTPD5/DNAJC30/STAT3/PGM2L1/PKM/ALDOC/VCP/OGDH/HTR2A/PFKFB4/NUP153/NME4/PINK1/DDIT4/VPS9D1/GALK1/PFKFB2/NUP88/ENO3/PRKAG2/NME3/POM121C/AK4/NUP205/RAE1/NUP50/IMPDH1/ALDOA/IL4/CTPS2/UCK2/INSR/NUPR1/SPHK2/NUP93/PFKL/ALDOB/NUP35/NME9/AAAS/TAZ/TGFB1/NUP62/P2RX7/SEH1L/NCOR1/NME2	62
BP	GO:0006979	response to oxidative stress	141/4749	451/18670	0.00281	0.03244	0.02639	PPIF/TXNIP/CDK1/NR4A3/FOSL1/KLF2/IL10/GSKIP/MELK/KLF4/CCNA2/TREX1/LDHA/SIRPA/NCF4/MCL1/MPV17/MMP9/SFPQ/VKORC1L1/PML/TNF/HSPA1A/RRM2B/CYBB/TLR4/NOL3/MAP1LC3A/GPX1/ABCD1/PLEKHA1/RIPK3/FXN/PON2/SRC/ETV5/NUDT1/HMOX1/PRDX3/PPARGC1B/CFLAR/MAPKAP1/BTK/ATP13A2/CDK2/AXL/PKD2/ATF4/PRDX5/RPS3/ACOX2/HBA2/NQO1/FOXO1/BRF2/DHFR/SDC1/CBX8/MAP3K5/PINK1/LIAS/ROMO1/AIF1/EZH2/ERCC8/FANCC/BAK1/SP1/IPCEF1/TP53INP1/ARG1/GPX4/TLR6/PARK7/STK25/JUN/PPP5C/UBE3A/ERCC2/CRK/EPAS1/ECT2/MPO/ARNTL/CYBA/ZC3H12A/XRCC1/DAPK1/TRAF2/PRDX6/SIRT2/SGK2/ADIPOQ/PSMB5/RBM11/PRNP/FER/STX2/ALDH3B1/HBB/DHRS2/HMOX2/NDUFA12/SLC23A2/GCLC/ERCC6L2/GGT7/MTR/STAU1/RAD52/FGF8/TPM1/STAT1/VNN1/RBPMS/PYROXD1/CCS/NEIL1/XPA/ADPRHL2/NCF1/ATRN/FOS/GSS/OGG1/WRN/TXNRD2/ATG7/NET1/MGMT/MAPK1/ADAM9/ANGPTL7/SESN2/PRDX1/ERCC1/BAD/FYN/NME2/SIRT1/DUSP1	141
BP	GO:1902115	regulation of organelle assembly	67/4749	194/18670	0.002855	0.03289	0.02676	GPSM2/SDC4/FSCN1/STIL/CSF2/HCK/SPAG5/PLK4/MTMR3/KCTD17/SMC3/CHMP2B/TNF/GSN/HSPA1A/PLK2/PLK1/CENPJ/SRC/ARHGEF5/NUMA1/ARHGEF2/SDCBP/NTRK3/STAM/ATMIN/KAT2A/HTT/ARHGAP35/PIKFYVE/MDM1/SDC1/PINK1/EZR/CYLD/CDK10/ULK1/PAN3/ZMYND10/STYXL1/MARK4/KIAA1324/C10orf90/ALMS1/WRAP73/LRFN4/UBQLN2/NPRL3/CHMP1A/PTPRS/LRSAM1/CHMP2A/BMP10/NUPR1/PIP4K2A/AKAP13/SMC1A/RALB/SENP6/PIP4K2B/PHF23/TRAPPC12/CEP97/SYNE2/NUP62/RAB1B/NPRL2	67
BP	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	14/4749	27/18670	0.002898	0.03327	0.02707	CDK1/DTL/HSPA2/CDC25A/CDC25C/WNT10B/CCNB1/FBXO5/DBF4B/BRD4/PBX1/MTA3/CDC25B/CCND1	14
BP	GO:0032673	regulation of interleukin-4 production	14/4749	27/18670	0.002898	0.03327	0.02707	CD86/NLRP3/CD83/IRF4/TNFSF4/LGALS9/FOXP3/HAVCR2/HLA-E/CEBPB/CD3E/RARA/ZFPM1/GATA3	14
BP	GO:0042254	ribosome biogenesis	97/4749	297/18670	0.002974	0.03409	0.02773	RPL3/RPS8/RPL10A/RPS27/RPL35/RPL38/RPS10/TRAF7/MRPL22/PPAN/RPL23A/USP36/NUDT16/XRN2/RPS5/RPL5/RPL26/RPS6/RPS15/RRP1/MRPS11/RPL7/RPL6/NSUN4/NOP10/ISG20/DDX27/NOL9/BYSL/POP5/RPS19/BRIX1/NSUN5P1/ABCE1/FASTKD2/PA2G4/ERI3/FAM207A/RIOK1/RPS16/SART1/SBDS/MRPL20/RPS9/NUP88/RPL14/NOLC1/MRPL36/MRPS2/YBEY/DDX17/ZNHIT3/NOP14/EXOSC2/TRMT112/NPM3/MYBBP1A/DDX54/UTP20/EMG1/BOP1/RPL12/UTP23/SDAD1/RPSA/BTRC/FBL/FDXACB1/RRNAD1/METTL16/WDR12/ABT1/TEX10/RPS28/ZCCHC4/MRPL10/NOM1/RPL7A/MRTO4/ESF1/MDN1/URB1/C1QBP/RRP8/RPP30/RPL11/RPF1/GTF2H5/RCL1/UTP3/TFB2M/CUL4A/DDX31/NGDN/EXOSC9/MALSU1/SIRT1	97
BP	GO:0090224	regulation of spindle organization	19/4749	41/18670	0.002992	0.03423	0.02785	GPSM2/TPX2/TACC3/SPAG5/SMC3/CHMP2B/HSPA1A/PLK1/FSD1/PSRC1/NUMA1/RAE1/CHMP1A/CHMP2A/SMC1A/MAP9/SENP6/CEP97/NUP62	19
BP	GO:0034340	response to type I interferon	38/4749	99/18670	0.003017	0.03428	0.02788	EGR1/IRF7/IFIT1/PTPN6/IRF4/ISG15/TREX1/OAS2/GBP2/MX1/IRF5/PTPN1/MMP12/RSAD2/IFITM2/HLA-H/IFI6/HLA-G/BST2/IFIT3/OASL/ISG20/ABCE1/HLA-E/SCRIB/IFITM3/IRAK1/IFITM1/IRF3/SAMHD1/OAS1/CNOT7/YTHDF3/IFI35/IFIT2/STAT1/IP6K2/JAK1	38
BP	GO:0072527	pyrimidine-containing compound metabolic process	38/4749	99/18670	0.003017	0.03428	0.02788	ACPP/DCTPP1/TYMP/APOBEC3H/TYMS/DHODH/AGPAT3/TK1/MTOR/TPK1/AGPAT2/CMPK2/APOBEC3B/ERH/DTYMK/AK5/RRM1/AK3/NME4/UPRT/DCTD/AICDA/NME3/DPYD/ENTPD4/TAMM41/NT5E/LCLAT1/CMPK1/CTPS2/UCK2/PRPS1/NEIL1/NME9/OGG1/GPAT2/MAPK1/NME2	38
BP	GO:0006809	nitric oxide biosynthetic process	31/4749	77/18670	0.003018	0.03428	0.02788	IL1B/ICAM1/KLF2/IL10/ACP5/KLF4/RAC1/PTGIS/SIRPA/CLEC7A/TNF/TLR4/DDAH2/MTOR/TSPO/CLU/PKD2/NQO1/CD47/AIF1/GCHFR/ATP2B4/TLR6/ZC3H12A/CD34/HBB/INSR/SPR/KLRK1/CX3CR1/KHSRP	31
BP	GO:0031397	negative regulation of protein ubiquitination	31/4749	77/18670	0.003018	0.03428	0.02788	ISG15/CDK5/DNAJA1/HSPA1A/MTOR/SMAD7/TSPO/DTX3L/RPL5/FBXO5/ARRB1/CRY1/PER2/RPS3/N4BP1/UBXN1/RPL23/NXN/TRIM44/LIMK1/CHP1/PARK7/RASD2/USP44/PRKCE/BAG2/GCLC/MAD2L2/RPL11/GLMN/FYN	31
BP	GO:0009206	purine ribonucleoside triphosphate biosynthetic process	60/4749	171/18670	0.00306	0.03469	0.02822	TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/GPI/CBFA2T3/SIRT6/HK2/NUP98/ENTPD5/DNAJC30/STAT3/PGM2L1/PKM/ALDOC/VCP/OGDH/HTR2A/PFKFB4/NUP153/NME4/PINK1/DDIT4/VPS9D1/GALK1/PFKFB2/NUP88/ENO3/PRKAG2/NME3/POM121C/AK4/NUP205/RAE1/NUP50/IMPDH1/ALDOA/IL4/INSR/NUPR1/SPHK2/NUP93/PFKL/ALDOB/NUP35/NME9/AAAS/TAZ/TGFB1/NUP62/P2RX7/SEH1L/NCOR1/NME2	60
BP	GO:0019318	hexose metabolic process	83/4749	249/18670	0.003084	0.03485	0.02835	SLC35A2/TPI1/PHLDA2/IGFBP4/GAPDH/HK1/PFKFB3/CHST15/GLB1/ENO1/PGAM1/PFKP/ATF3/GPI/MPI/TNF/PPP1CB/HK2/SLC25A1/BRAT1/PMAIP1/MTOR/SDS/CRTC2/SRC/PGM2L1/PKM/FABP5/ALDOC/PDHB/CRY1/PFKFB4/KAT2A/MAN2B1/ATF4/PER2/IGFBP3/FOXO1/GALK2/MDH2/RORC/FUCA2/GALK1/PFKFB2/SLC45A3/DLAT/ADIPOR1/ENO3/MAEA/PPP1R3E/C1QTNF3/TFAP2B/EPM2AIP1/GALM/OAS1/GSK3A/PHKG2/ALDOA/GHRL/GNMT/ADIPOQ/CPT1A/DGAT2/SERP1/ACACB/FUT6/INSR/GALT/SLC35B4/PFKL/ALDOB/FUCA1/PPARD/ALDH5A1/CLK2/COX11/OMA1/SESN2/AKR1A1/PDX1/BAD/PPP1R3B/SIRT1	83
BP	GO:0007080	mitotic metaphase plate congression	20/4749	44/18670	0.003112	0.03485	0.02835	KIF2C/CDCA8/KIF14/KIFC1/CDCA5/CDT1/KIF18A/CHMP2B/NUF2/PSRC1/CCNB1/CENPE/NDC80/BOD1/PIBF1/CHMP1A/CHMP2A/CHAMP1/NUP62/SEH1L	20
BP	GO:0007077	mitotic nuclear envelope disassembly	8/4749	12/18670	0.003123	0.03485	0.02835	CDK1/CCNB2/PLK1/CCNB1/PRKCA/PRKCB/NEK9/LPIN1	8
BP	GO:0009086	methionine biosynthetic process	8/4749	12/18670	0.003123	0.03485	0.02835	MRI1/MTHFD1/BHMT/MTRR/MTAP/ENOPH1/MTR/BHMT2	8
BP	GO:0051095	regulation of helicase activity	8/4749	12/18670	0.003123	0.03485	0.02835	IFIT1/MSH6/MCM2/GTF2H2/POT1/SSBP1/MNAT1/SIRT1	8
BP	GO:0051549	positive regulation of keratinocyte migration	8/4749	12/18670	0.003123	0.03485	0.02835	HBEGF/MMP9/MTOR/MAPRE2/IQSEC1/ARF6/HAS2/ADAM9	8
BP	GO:0051988	regulation of attachment of spindle microtubules to kinetochore	8/4749	12/18670	0.003123	0.03485	0.02835	NEK2/SPAG5/RACGAP1/CCNB1/ECT2/SIRT2/APC/CDC42	8
BP	GO:0060670	branching involved in labyrinthine layer morphogenesis	8/4749	12/18670	0.003123	0.03485	0.02835	IL10/ST14/SOCS3/SPINT1/ADM/RSPO3/FZD5/GCM1	8
BP	GO:0070486	leukocyte aggregation	8/4749	12/18670	0.003123	0.03485	0.02835	IL1B/NR4A3/CD44/RAC2/S100A8/SEMA4D/HAS2/ZAP70	8
BP	GO:2001169	regulation of ATP biosynthetic process	37/4749	96/18670	0.00313	0.03487	0.02837	SEC13/TREX1/PFKFB3/ENO1/PGAM1/CBFA2T3/SIRT6/NUP98/ENTPD5/DNAJC30/STAT3/VCP/HTR2A/PFKFB4/NUP153/PINK1/DDIT4/PFKFB2/NUP88/PRKAG2/POM121C/AK4/NUP205/RAE1/NUP50/IL4/INSR/NUPR1/SPHK2/NUP93/NUP35/AAAS/TAZ/NUP62/P2RX7/SEH1L/NCOR1	37
BP	GO:0120163	negative regulation of cold-induced thermogenesis	21/4749	47/18670	0.0032	0.03557	0.02894	NOTCH1/PCTP/ACOT11/TLR4/ARRDC3/WNT10B/TFE3/RBPJ/ATF4/MAP2K6/TLE3/PLCL2/DDIT3/IL18R1/ACVR2B/ARNTL/IP6K1/ADIPOQ/LNPEP/ID1/PGAM5	21
BP	GO:0031343	positive regulation of cell killing	28/4749	68/18670	0.003204	0.03557	0.02894	CD1E/IL21/GAPDH/CLEC7A/ULBP2/CD1A/RAET1E/CD1C/HLA-H/HLA-G/SH2D1A/CD1B/CD1D/PGLYRP3/PTPRC/HLA-E/MICA/IL12RB1/ARG1/LAG3/CADM1/LAMP1/ULBP1/TYROBP/KLRK1/P2RX7/BAD/IL23A	28
BP	GO:0071706	tumor necrosis factor superfamily cytokine production	59/4749	168/18670	0.00322	0.03559	0.02895	TWIST1/CD86/IL10/ACP5/PTPN6/BCL3/TREX1/SIRPA/TIRAP/CLEC7A/GPNMB/LGALS9/HMGB1/ZFP36/TNFRSF8/CYBB/TLR4/LILRA2/FOXP3/CARD9/TSPO/CCR2/ARHGEF2/CCL3/CLU/HAVCR2/AXL/CD33/IRAK3/PTPRC/HLA-E/CD47/TLR2/NOD2/IL27RA/DEFB114/SYT11/AZI2/NFKBIL1/CYBA/NLRC3/ZC3H12A/LILRA5/IFNGR1/GHRL/ADIPOQ/IL4/CD34/RIPK2/MAPKAPK2/TYROBP/DICER1/SPHK2/FZD5/DDT/RARA/PTAFR/CX3CR1/IL23A	59
BP	GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism	75/4749	222/18670	0.003226	0.03559	0.02895	NOTCH1/TOP2A/CSF1R/IFIT1/ISG15/GAPDH/ANXA2P2/LGALS9/APOBEC3H/PML/SMC3/CHMP2B/KPNA2/MX1/TNF/ZFP36/GSN/TRIM25/ANXA2/TRIM26/SMARCB1/IFIT5/RSAD2/SNF8/FCN1/IFITM2/PPIH/TRIM62/CCL3/BST2/MORC2/CD74/OASL/LGALS1/ISG20/SMARCA4/TBC1D20/FUCA2/CFL1/TRIM13/BANF1/SP1/IFITM3/AICDA/IFITM1/ARG1/POLR2I/MID2/JUN/FMR1/TAF11/CCNK/RAD23A/ZNF639/POLR2C/ZC3H12A/OAS1/CNOT7/IFI16/ILF3/ZC3HAV1/KRT6A/CHMP2A/STAU1/POLR2J/TRIM35/STAT1/STOM/NUCKS1/POLR2A/SETDB1/CHMP3/BAD/TRIM15/TRIM5	75
BP	GO:0072698	protein localization to microtubule cytoskeleton	22/4749	50/18670	0.00326	0.03559	0.02895	STIL/FAM83D/TTK/AURKA/KIF20B/SPAG5/MAPRE2/NUMA1/DVL1/MID1/MID2/MARK4/PIBF1/CEP192/NSFL1C/MAP1A/CEP72/APC/CHAMP1/PARD6A/MCPH1/NUP62	22
BP	GO:1903322	positive regulation of protein modification by small protein conjugation or removal	49/4749	135/18670	0.00327	0.03559	0.02895	NDFIP2/UBE2C/CDC20/FANCI/GORASP1/UBE2S/HSPA5/DERL1/ARRDC3/PLK1/PIAS3/SMAD7/ARRB1/VCP/UBE2I/UBB/CRY1/UBE2N/RNF40/TOLLIP/PINK1/PIAS1/ARRDC4/NOD2/FKBP1A/TANK/GNL3/UBE3A/RASD2/TOPORS/ZC3H12A/DCUN1D4/BIRC3/GSK3A/PIAS4/CDC14B/RIPK2/TRAF6/BIRC7/MTA1/RAB1A/WDR48/PSMD10/PHF23/BMI1/PEF1/FBXO4/TRIB3/MAGEA2B	49
BP	GO:0000002	mitochondrial genome maintenance	15/4749	30/18670	0.003273	0.03559	0.02895	TOP3A/TYMP/MPV17/RRM2B/AKT3/PIF1/MSTO1/DNAJA3/SLC25A36/DNA2/POLG2/SSBP1/SLC25A4/ATG7/SESN2	15
BP	GO:0000027	ribosomal large subunit assembly	15/4749	30/18670	0.003273	0.03559	0.02895	RPL3/RPL38/TRAF7/PPAN/RPL23A/RPL5/RPL6/BRIX1/FASTKD2/MRPL20/BOP1/RPL12/MRTO4/MDN1/RPL11	15
BP	GO:0032607	interferon-alpha production	15/4749	30/18670	0.003273	0.03559	0.02895	IRF7/IL10/TLR8/TREX1/HMGB1/IRF5/TLR4/MMP12/HAVCR2/AZI2/NLRC3/IRF3/RIPK2/PTPRS/STAT1	15
BP	GO:0071480	cellular response to gamma radiation	15/4749	30/18670	0.003273	0.03559	0.02895	EGR1/CDKN1A/TREX1/HSPA5/RPL26/XRCC6/ELK1/BCL2L1/CYBA/YAP1/ATR/CHEK2/GTF2H5/ATM/WRN	15
BP	GO:1902751	positive regulation of cell cycle G2/M phase transition	15/4749	30/18670	0.003273	0.03559	0.02895	CDK1/DTL/HSPA2/DYRK3/CDC25A/CDC25C/WNT10B/CCNB1/FBXO5/DBF4B/BRD4/PBX1/MTA3/CDC25B/CCND1	15
BP	GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus	26/4749	62/18670	0.003283	0.03559	0.02895	IL10/BATF/EXO1/BCL6/TNFSF4/TFRC/HMGB1/MSH6/FOXP3/SWAP70/CCR6/TP53BP1/PTPRC/SUPT6H/AICDA/IL27RA/RNF8/APLF/TNFSF13/IL4/MAD2L2/ATM/RAG2/TGFB1/ERCC1/RNF168	26
BP	GO:0002753	cytoplasmic pattern recognition receptor signaling pathway	26/4749	62/18670	0.003283	0.03559	0.02895	IRF7/TIFA/HSPA1A/TLR4/SEC14L1/UBB/UBE2N/MAP2K6/NPLOC4/RPS27A/CYLD/UBA52/NOD2/IRAK1/TAB1/NFKBIA/IRF3/BIRC3/RIPK2/C1QBP/TRAF6/TSPAN6/ANKRD17/ZCCHC3/USP17L2/TRIM15	26
BP	GO:0006220	pyrimidine nucleotide metabolic process	26/4749	62/18670	0.003283	0.03559	0.02895	DCTPP1/TYMS/DHODH/AGPAT3/AGPAT2/CMPK2/ERH/DTYMK/AK5/AK3/NME4/UPRT/DCTD/NME3/ENTPD4/TAMM41/LCLAT1/CMPK1/CTPS2/UCK2/PRPS1/NEIL1/NME9/OGG1/GPAT2/NME2	26
BP	GO:0006521	regulation of cellular amino acid metabolic process	26/4749	62/18670	0.003283	0.03559	0.02895	PSMD8/ATCAY/PSMD1/PSMD2/PSMF1/NQO1/OAZ3/BHMT/PSMD9/ATP2B4/PSMA5/PARK7/PSMB7/OAZ2/PSMD5/PSME2/PSMB5/PSMB4/PSMA3/OAZ1/PSMD10/PSMB1/PSMD7/PSMB3/PSMC5/PSMD11	26
BP	GO:0016444	somatic cell DNA recombination	26/4749	62/18670	0.003283	0.03559	0.02895	IL10/BATF/EXO1/BCL6/TNFSF4/TFRC/HMGB1/MSH6/FOXP3/SWAP70/CCR6/TP53BP1/PTPRC/SUPT6H/AICDA/IL27RA/RNF8/APLF/TNFSF13/IL4/MAD2L2/ATM/RAG2/TGFB1/ERCC1/RNF168	26
BP	GO:0036297	interstrand cross-link repair	23/4749	53/18670	0.003295	0.03563	0.02898	FANCI/FANCG/MSH6/RAD51/RAD51AP1/UBB/RFWD3/RPS27A/UBA52/FANCC/RNF8/FANCF/XRCC3/EME1/ERCC6L2/ATR/POLN/XPA/NUCKS1/WDR48/FAN1/ERCC1/RNF168	23
BP	GO:1903409	reactive oxygen species biosynthetic process	45/4749	122/18670	0.003306	0.03563	0.02898	IL1B/ICAM1/KLF2/IL10/ACP5/KLF4/RAC1/PTGIS/SIRPA/CLEC7A/TNF/CYBB/TLR4/DDAH2/CTNS/MTOR/ABCD1/STAT3/TSPO/ABCD2/CFLAR/CLU/PKD2/NQO1/CD47/AIF1/GCHFR/ATP2B4/RAB27A/TLR6/PARK7/GBF1/MPO/ZNF205/CYBA/ZC3H12A/CD34/HBB/INSR/SPHK2/SPR/KLRK1/CX3CR1/KHSRP/FYN	45
BP	GO:1903578	regulation of ATP metabolic process	45/4749	122/18670	0.003306	0.03563	0.02898	PPIF/CDK1/SEC13/TREX1/PFKFB3/ENO1/PGAM1/CBFA2T3/SIRT6/NUP98/SLC25A23/ENTPD5/ABCD1/DNAJC30/STAT3/TSPO/CCNB1/VCP/HTR2A/PFKFB4/NUP153/PINK1/DDIT4/PFKFB2/NUP88/PRKAG2/PARK7/POM121C/AK4/NUP205/RAE1/NUP50/IL4/ISCU/INSR/NUPR1/SPHK2/NUP93/NUP35/AAAS/TAZ/NUP62/P2RX7/SEH1L/NCOR1	45
BP	GO:0001912	positive regulation of leukocyte mediated cytotoxicity	24/4749	56/18670	0.003309	0.03563	0.02898	CD1E/IL21/ULBP2/CD1A/RAET1E/CD1C/HLA-H/HLA-G/SH2D1A/CD1B/CD1D/PTPRC/HLA-E/MICA/IL12RB1/ARG1/LAG3/CADM1/LAMP1/ULBP1/TYROBP/KLRK1/P2RX7/IL23A	24
BP	GO:0000717	nucleotide-excision repair, DNA duplex unwinding	12/4749	22/18670	0.003339	0.03565	0.02901	DDB2/UBB/RPS27A/RAD23B/UBA52/ERCC2/GTF2H2/GTF2H1/CETN2/GTF2H5/XPA/CUL4A	12
BP	GO:0031342	negative regulation of cell killing	12/4749	22/18670	0.003339	0.03565	0.02901	CEACAM1/LGALS9/HLA-G/HAVCR2/PTPRC/HLA-E/MICA/CRK/IL7R/IL13/IL4/KRT6A	12
BP	GO:0032069	regulation of nuclease activity	12/4749	22/18670	0.003339	0.03565	0.02901	OAS2/HMGB1/HSPA1A/OASL/RPS3/TERF1/ABCE1/OAS1/DDX11/NEIL1/TERF2/SIRT1	12
BP	GO:0033233	regulation of protein sumoylation	12/4749	22/18670	0.003339	0.03565	0.02901	EGR1/PIAS3/UBE2I/TOLLIP/PIAS1/GNL3/PARK7/RASD2/HMG20A/PIAS4/HMG20B/MAGEA2B	12
BP	GO:0140112	extracellular vesicle biogenesis	12/4749	22/18670	0.003339	0.03565	0.02901	SDC4/SNF8/SDCBP/ATP13A2/STAM/SDC1/ARRDC4/HGS/RAB27A/CD34/ARRDC1/CHMP2A	12
BP	GO:0051495	positive regulation of cytoskeleton organization	76/4749	226/18670	0.00348	0.0371	0.03018	CDC42EP4/GPSM2/SDC4/ICAM1/FES/HCK/RAC1/CYFIP1/SPAG5/CDK5/PLK4/NF2/FHOD1/SNX9/GSN/HSPA1A/CTTN/CENPJ/MTOR/BAG4/PSRC1/CDC42EP1/PFDN2/SWAP70/TENM1/ARHGEF5/NUMA1/CORO1B/NTRK3/PDXP/TGFB3/WHAMMP3/PAK1/PFN2/POC1A/RPS3/HIP1R/ARPC1B/TERF1/PICK1/CORO1A/CD47/VASP/LIMCH1/CFL1/S100A10/ARPC5/LIMK1/SH3PXD2B/PRKCE/ACTR3B/WDR1/SFRP1/FER/NSFL1C/KATNBL1/BMP10/ARF6/TPM1/ARL2/SORBS3/NTF3/WHAMM/AP1AR/SLAIN2/ID1/BCAS3/C15orf62/SEMA5A/CDC42/WAS/FMN1/NUP62/P2RX7/CCL27/RAC3	76
BP	GO:0034599	cellular response to oxidative stress	98/4749	302/18670	0.003523	0.03748	0.0305	PPIF/CDK1/NR4A3/KLF2/IL10/GSKIP/MELK/KLF4/CCNA2/TREX1/SIRPA/NCF4/MCL1/MPV17/MMP9/SFPQ/VKORC1L1/PML/TNF/HSPA1A/CYBB/TLR4/NOL3/MAP1LC3A/GPX1/ABCD1/PLEKHA1/RIPK3/FXN/SRC/ETV5/HMOX1/PRDX3/PPARGC1B/CFLAR/MAPKAP1/BTK/ATP13A2/CDK2/AXL/PKD2/ATF4/PRDX5/RPS3/NQO1/FOXO1/BRF2/DHFR/CBX8/MAP3K5/PINK1/ROMO1/AIF1/EZH2/FANCC/TP53INP1/ARG1/TLR6/PARK7/STK25/JUN/PPP5C/CRK/EPAS1/ECT2/MPO/ARNTL/CYBA/ZC3H12A/DAPK1/TRAF2/PRDX6/SIRT2/RBM11/FER/ALDH3B1/DHRS2/ERCC6L2/MTR/STAU1/RAD52/TPM1/VNN1/PYROXD1/CCS/ADPRHL2/NCF1/FOS/TXNRD2/ATG7/NET1/MGMT/MAPK1/SESN2/PRDX1/FYN/NME2/SIRT1	98
BP	GO:0000097	sulfur amino acid biosynthetic process	10/4749	17/18670	0.003544	0.03749	0.0305	GGT1/CTH/MRI1/MTHFD1/BHMT/MTRR/MTAP/ENOPH1/MTR/BHMT2	10
BP	GO:0033262	regulation of nuclear cell cycle DNA replication	10/4749	17/18670	0.003544	0.03749	0.0305	CDT1/BCL6/DBF4/DBF4B/TERF1/AICDA/CHEK2/WIZ/TIPIN/TERF2	10
BP	GO:0061687	detoxification of inorganic compound	10/4749	17/18670	0.003544	0.03749	0.0305	MT1E/MT2A/MT1X/MT1H/MT1G/PARK7/MT1A/MT1B/MT1M/MT1F	10
BP	GO:0032103	positive regulation of response to external stimulus	104/4749	323/18670	0.003551	0.03749	0.0305	CXCL13/IL1B/VEGFA/IL18/IL21/ITGA2/WNK1/ABCC1/CCL3L3/RAC1/TTBK1/IL17A/GRN/C2CD4B/TIRAP/TNFSF4/CNTF/CCR1/DAPK2/CLEC7A/LGALS9/HMGB1/TNF/CSF1/TLR4/CXCL10/SERPINE1/LDLR/FFAR2/PDCD4/SWAP70/CCR6/CCR2/CCR4/TGM2/TIAM1/BTK/CCL3/PTGER4/NTRK3/HAVCR2/CD74/FFAR3/S1PR1/CD180/CASR/RPS19/PRKCA/HLA-E/CD47/AIF1/CCL18/SCARF1/TLR2/NOD2/LRP1/OSM/ARG1/LTA/CNR1/TLR6/FPR2/PARK7/CYP27B1/C3AR1/IL17RC/NFKBIA/DEFB114/RAC2/CEBPB/IDO1/CYBA/KLKB1/NEAT1/LILRA5/RARRES2/GHRL/S100A8/F3/PLA2G2A/RIPK2/LRSAM1/CD6/MGST2/C1QBP/KLK5/NUPR1/TRAF6/TNFSF11/CCL7/NTF3/THBS4/DDT/ANKRD17/TGFB1/SEMA5A/ZCCHC3/C2CD4A/PDGFB/USP17L2/CCL27/VEGFC/TRIM15/IL23A	104
BP	GO:0009145	purine nucleoside triphosphate biosynthetic process	60/4749	172/18670	0.003553	0.03749	0.0305	TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/GPI/CBFA2T3/SIRT6/HK2/NUP98/ENTPD5/DNAJC30/STAT3/PGM2L1/PKM/ALDOC/VCP/OGDH/HTR2A/PFKFB4/NUP153/NME4/PINK1/DDIT4/VPS9D1/GALK1/PFKFB2/NUP88/ENO3/PRKAG2/NME3/POM121C/AK4/NUP205/RAE1/NUP50/IMPDH1/ALDOA/IL4/INSR/NUPR1/SPHK2/NUP93/PFKL/ALDOB/NUP35/NME9/AAAS/TAZ/TGFB1/NUP62/P2RX7/SEH1L/NCOR1/NME2	60
BP	GO:0051443	positive regulation of ubiquitin-protein transferase activity	16/4749	33/18670	0.003584	0.03776	0.03072	UBE2C/CDC20/GORASP1/UBE2S/ARRDC3/PLK1/UBE2N/PINK1/ARRDC4/TOPORS/DCUN1D4/CDC14B/RAB1A/BMI1/TRIB3/MAGEA2B	16
BP	GO:1903038	negative regulation of leukocyte cell-cell adhesion	47/4749	129/18670	0.003595	0.03782	0.03077	CD86/SDC4/WNK1/ADORA2A/IL10/KLF4/CD80/PTPN6/BCL6/CBFB/TNFSF4/LGALS3/GPNMB/CEACAM1/LGALS9/HMGB1/IL2RA/BTN2A2/TNFRSF21/FOXP3/ADTRP/CTLA4/IL4R/SMAD7/HLA-G/TIGIT/HAVCR2/CD74/CLEC4G/HLX/DUSP22/LILRB2/ARG1/LAG3/ERBB2/CEBPB/IDO1/DTX1/PDCD1LG2/ZC3H12A/NRARP/DLG5/PRNP/TGFB1/GLMN/JAK3/LRRC32	47
BP	GO:0007569	cell aging	43/4749	116/18670	0.003616	0.03791	0.03084	TWIST1/FOXM1/CDK1/CDKN1A/ICAM1/CDKN2B/SRF/BCL6/TP63/PML/PLK2/BRCA2/AKT3/SERPINE1/MTOR/LMNA/VASH1/PDCD4/FBXO5/HLA-G/LIMS1/DNAJA3/NAMPT/ROMO1/CDKN2A/BCL2L12/CHEK1/ARNTL/MAP3K3/YPEL3/BGLAP/ATR/CHEK2/ATM/WRN/SMC5/NUP62/ERCC1/KAT6A/ILK/MAGEA2B/TERF2/SIRT1	43
BP	GO:0021782	glial cell development	43/4749	116/18670	0.003616	0.03791	0.03084	IL1B/ADORA2A/NTRK2/TTBK1/GRN/CNTF/CDK5/CD9/ASCL1/TNF/GSN/SKI/TLR4/LDLR/PRDM8/FA2H/CLU/NTRK3/EIF2B3/PICK1/MPP5/NDRG1/TLR2/DRD1/LRP1/FPR2/ERCC2/ADAM22/SOX11/VIM/POU3F1/B4GALT5/SIRT2/IFNGR1/S100A8/C1QA/DICER1/MED12/DLL1/NKX6-2/TGFB1/HDAC10/ILK	43
BP	GO:0001933	negative regulation of protein phosphorylation	134/4749	429/18670	0.00364	0.03811	0.031	TWIST1/LIF/IL1B/PBK/CD109/FOXM1/PTPN13/CDKN1A/WNK1/MVP/DUSP10/CAMK2N2/ADORA2A/DUSP4/TRIB1/MICAL1/CDKN2B/GSKIP/RASSF2/KLF4/PTPN6/PMEPA1/DUSP6/SPRED2/HEXIM1/SIRPA/SNX25/DNAJA1/CEACAM1/CORO1C/ATF3/NF2/PPP2R1A/LRRK1/TLR4/CHRNA10/BAX/BTN2A2/UBE2B/PTPN1/PLK1/CDKN2C/GADD45A/MTOR/MYADM/SMAD7/PARP14/PDCD4/SORL1/CCNB1/SOCS3/FGFR1OP/DUSP5/SFN/PDE4D/ARRB1/SAMSN1/NTRK3/IGF1R/WWTR1/IGFBP3/SMAD6/FKTN/IRAK3/FOXO1/PTK6/SYNJ2BP/DUSP16/PINK1/PTPRC/EZR/CYLD/DDIT4/SH3BP5L/DUSP22/DVL1/PPP2CA/CHORDC1/PRDM15/BAK1/CDKN2A/GBA/DTNBP1/NDRG2/THY1/SIRT3/BDKRB2/TAOK3/PRKAG2/CHP1/LDLRAD4/RAPGEF1/PARK7/JUN/PPP5C/FKBP8/GGNBP2/PIBF1/DEFB114/DEPTOR/ZC3H12A/RABGEF1/C3orf33/DUSP18/SFRP1/SIRT2/ADIPOQ/TAF7/PRNP/TESC/AIDA/LRP6/NNT/TIMP3/SEMA4D/STK38/GNAQ/ZBED3/DUSP14/APC/PARD6A/NTF3/ZNF675/PSMD10/TGFB1/UCHL1/NUP62/P2RX7/NCOR1/PAK2/TRIB3/ILK/SIRT1/DUSP1	134
BP	GO:0034976	response to endoplasmic reticulum stress	93/4749	285/18670	0.003673	0.03838	0.03122	CHAC1/ATP6V0D1/ATF3/PML/SERINC3/HSPA5/CREB3L2/SDF2L1/SERP2/HSPA1A/DERL1/BAX/TPP1/PTPN1/ZBTB17/UBXN6/TRIM25/PMAIP1/LMNA/SYVN1/SEC16A/POMT2/VCP/ATP2A1/DNAJB12/CLU/USP19/HERPUD1/ATF4/PDIA4/ASNS/CTH/UBXN1/CCL2/NPLOC4/RASGRF2/FBXO27/UBE4A/SGTA/TNFRSF10B/MAP3K5/UBE2G2/BCAP31/TRIM13/FLOT1/EXTL2/PARP16/BAK1/TMEM117/SEC61B/DDIT3/RCN3/CREBRF/PARK7/JUN/JKAMP/TXNDC12/CEBPB/SDF2/EDEM2/BCL2L1/FICD/GSK3A/BRSK2/KLHDC3/YIF1A/UBQLN2/DDX11/TRAF2/EIF2AK3/ERN1/RNF139/SERP1/CANX/TMEM67/RNF121/MBTPS2/NUPR1/PPP1R15A/TMUB2/FBXO44/THBS4/HERPUD2/TMEM33/DNAJB2/CCND1/UBAC2/SESN2/PDX1/SHC1/RNF186/TRIB3/SIRT1	93
BP	GO:0031333	negative regulation of protein complex assembly	50/4749	139/18670	0.003686	0.03846	0.03129	KIF14/PMEPA1/THRA/EIF4EBP1/CAPZB/HMGB1/GSN/MYADM/SORL1/TMOD2/SRC/CAPG/ARHGEF2/TMC8/CLIP3/CLU/PTGER4/ADD3/PFN2/HIP1R/LMO4/SMAD6/TMSB4Y/SPTBN1/STMN1/TRIOBP/TWF2/TFIP11/ULK1/SPTAN1/MKKS/INSIG1/GBA/STYXL1/CAPZA1/LDLRAD4/PARK7/TUBB4A/KANK3/NLRC3/TMSB15A/VILL/SIRT2/PEX5/CDC42/ZNF451/CDH5/CRBN/ADD2/TRIM9	50
BP	GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	38/4749	100/18670	0.003692	0.03846	0.03129	IL1B/CD1E/IL18/NLRP3/IL1R1/CD80/TNFSF4/TFRC/TNF/CD1A/FOXP3/CD1C/RSAD2/CCR2/HLA-H/HLA-G/TP53BP1/BTK/CD1B/CD1D/HLX/PTPRC/HLA-E/IL12RB1/IL27RA/LTA/IL18R1/TRAF2/TNFSF13/IL4/RIPK2/MAD2L2/TRAF6/FZD5/TGFB1/GATA3/P2RX7/IL23A	38
BP	GO:0001910	regulation of leukocyte mediated cytotoxicity	31/4749	78/18670	0.003807	0.03959	0.03221	CD1E/IL21/ICAM1/CEACAM1/LGALS9/ULBP2/CD1A/RAET1E/CD1C/RIPK3/HLA-H/HLA-G/SH2D1A/CD1B/HAVCR2/CD1D/PTPRC/HLA-E/MICA/IL12RB1/ARG1/LAG3/CADM1/CRK/IL7R/LAMP1/ULBP1/TYROBP/KLRK1/P2RX7/IL23A	31
BP	GO:0006007	glucose catabolic process	17/4749	36/18670	0.003835	0.03981	0.03239	TPI1/GAPDH/HK1/ENO1/PGAM1/PFKP/GPI/HK2/PGM2L1/PKM/ALDOC/PFKFB2/ENO3/ALDOA/PFKL/ALDOB/BAD	17
BP	GO:0120162	positive regulation of cold-induced thermogenesis	37/4749	97/18670	0.00384	0.03981	0.03239	G0S2/VEGFA/PLAC8/IL18/GADD45G/IRF4/THRA/SIRT6/IL4R/CCR2/SCD/HCRT/PPARGC1B/FABP5/GNAS/IGF1R/PER2/ACSL1/PRDM16/PRKAB2/KSR2/CNOT3/ADIPOR2/ADIPOR1/TSHR/EPAS1/CEBPB/ALMS1/IL13/GHRL/ADIPOQ/IL4/BSCL2/PTH2R/APC/OMA1/LPIN1	37
BP	GO:0007084	mitotic nuclear envelope reassembly	7/4749	10/18670	0.003891	0.04007	0.0326	PPP2R1A/REEP3/LMNA/REEP4/PPP2CA/BANF1/EMD	7
BP	GO:0033314	mitotic DNA replication checkpoint	7/4749	10/18670	0.003891	0.04007	0.0326	TICRR/CLSPN/CDC6/ORC1/TOPBP1/ZNF830/NAE1	7
BP	GO:0071104	response to interleukin-9	7/4749	10/18670	0.003891	0.04007	0.0326	STAT3/IL2RG/IL9R/STAT5A/STAT1/JAK3/JAK1	7
BP	GO:1903862	positive regulation of oxidative phosphorylation	7/4749	10/18670	0.003891	0.04007	0.0326	CDK1/CCNB1/VCP/PINK1/PARK7/ISCU/NUPR1	7
BP	GO:0000209	protein polyubiquitination	100/4749	310/18670	0.003936	0.04029	0.03278	ZNRF1/CCNF/RNF144A/UBE2C/DTL/UBE2A/CBFB/RFFL/UBE2S/FBXL19/DDB2/SPSB1/UBE2B/SYVN1/UBE2H/DTX3L/UBE3D/PSMD8/FBXL18/TTC3/UBB/PSMD1/PSMD2/KLHL3/MYLIP/UBE2N/FBXL14/PSMF1/RPS27A/RNF40/FBXO27/FBXO31/UBE4A/SMURF1/UBE2G2/RNF187/UBA52/ERCC8/TNKS2/TRIM44/NOD2/PSMD9/PSMA5/FBXL8/RNF8/ANAPC11/RNF19B/RNF216/RNF213/PSMB7/UBE3A/MGRN1/FBXW11/TOPORS/PSMD5/TPP2/C10orf90/SIAH2/ANAPC1/RLIM/PSME2/PRPF19/BTRC/TRAF2/HERC6/FBXL4/PSMB5/FBXO11/FBXO9/UBR2/LRSAM1/LNPEP/PSMB4/TRAF6/MKRN1/PSMA3/FBXL22/FBXL15/FBXL20/WSB1/FBXO44/IRF2BP1/UBE3B/PSMD10/ANAPC13/PSMB1/PSMD7/UBOX5/PSMB3/FBXO10/CDC16/PSMC5/FBXO4/RNF186/BARD1/RNF168/NHLRC3/UBE2W/PSMD11/TRIM5	100
BP	GO:0002719	negative regulation of cytokine production involved in immune response	13/4749	25/18670	0.003945	0.04029	0.03278	IL10/BCL6/TNF/FOXP3/SMAD7/HMOX1/BST2/TGFB3/IRAK3/ARG1/TGFB1/JAK3/CD96	13
BP	GO:0032616	interleukin-13 production	13/4749	25/18670	0.003945	0.04029	0.03278	IL18/NLRP3/IRF4/TNFSF4/LGALS9/TNFRSF21/HLA-E/PAEP/LILRA5/IL4/SPHK2/RARA/GATA3	13
BP	GO:0033522	histone H2A ubiquitination	13/4749	25/18670	0.003945	0.04029	0.03278	UBE2A/DDB2/UBE2B/RYBP/DTX3L/BCOR/RNF8/PCGF6/PCGF1/PCGF5/UBR2/BMI1/RNF168	13
BP	GO:0045662	negative regulation of myoblast differentiation	13/4749	25/18670	0.003945	0.04029	0.03278	NOTCH1/IL18/TNF/CXCL10/CCL17/DDIT3/SOX8/MBNL3/EID2B/DLL1/PPARD/TGFB1/SRA1	13
BP	GO:0051053	negative regulation of DNA metabolic process	55/4749	156/18670	0.00395	0.04029	0.03278	TWIST1/PPARG/BCL6/CDC6/GMNN/SMC3/MSH6/BRCA2/FOXP3/SRC/PARPBP/RMI2/HCRT/FBXO5/TP53BP1/PIF1/POLQ/MAGEF1/RPS3/ZRANB3/TERF1/TFIP11/TIMELESS/TNKS2/RECQL5/ACD/CTC1/AICDA/S100A11/ZNF93/POT1/ZNF830/ZNF91/XRCC1/MAPT-AS1/AUNIP/ADIPOQ/SMG6/MAD2L2/HELB/ATR/CHEK2/PAM16/SMC1A/TINF2/OGG1/ATM/ATG7/NMNAT1/KCNK2/GATA3/ERCC1/TIPIN/TERF2/DUSP1	55
BP	GO:1901216	positive regulation of neuron death	36/4749	94/18670	0.003991	0.04065	0.03307	EGR1/CASP9/GRN/MYBL2/MCL1/CDK5/ASCL1/TNF/TLR4/BAX/MTOR/CCL3/CLU/ATF4/NQO1/PAK3/MAP3K5/DDIT4/ITGA1/ZNF746/MAP3K11/DDIT3/TLR6/ELK1/JUN/TFAP2B/CTSZ/MAP2K4/PRNP/TYROBP/C1QA/NUPR1/FOS/ATM/BAD/FYN	36
BP	GO:0002532	production of molecular mediator involved in inflammatory response	29/4749	72/18670	0.004011	0.04072	0.03313	DUSP10/IL17A/GRN/SIRPA/CLEC7A/TLR4/SERPINE1/ABCD1/IL1R2/IL4R/PDCD4/ABCD2/P2RX1/BTK/BAP1/C5orf30/RPS19/ALOX5/NOD2/SNAP23/TLR6/IL17RC/IDO1/NLRC3/ZC3H12A/CHID1/CD6/CD96/SEH1L	29
BP	GO:0061180	mammary gland epithelium development	29/4749	72/18670	0.004011	0.04072	0.03313	VDR/IQGAP3/CSF1R/PTCH1/PML/CSF1/FOXB1/BRCA2/BAX/GPX1/MSX1/SRC/ETV5/KDM5B/SCRIB/CEBPB/LRP5L/DDR1/ZNF703/BTRC/ESR1/LRP6/TNFSF11/LBH/TGFB1/MGMT/MAPK1/CCND1/GATA3	29
BP	GO:0030099	myeloid cell differentiation	130/4749	416/18670	0.004061	0.04116	0.03348	LIF/IRF7/CD109/VEGFA/RELB/HMGB3/CSF2/NR4A3/PPARG/CASP9/KLF2/CSF1R/BATF/TRIB1/CDKN2B/FES/RASSF2/SRF/PTPN6/IRF4/ISG15/BCL6/IL17A/SPI1/DYRK3/CSF3R/CBFB/ZNF385A/TIRAP/TFRC/SFXN1/CCR1/ANXA2P2/LGALS3/CEACAM1/MMP9/UBD/PML/THRA/CBFA2T3/TNF/CSF1/ZFP36/HSPA1A/LRRK1/TLR4/PIAS3/MTOR/GAB2/ANXA2/ESRRA/SBNO2/STAT3/ZBTB46/SRC/PRDX3/PPARGC1B/TFE3/HSPA9/LILRB4/RPS6/GNAS/CCL3/TNRC6B/CD74/PIR/RBPJ/FAM20C/PRKX/JAG1/HOXB7/RPS19/PRKCA/TLR2/SNRK/MAEA/RASGRP4/MT1G/JUN/TOB2/ERCC2/NFKBIA/CA2/EPAS1/CEBPB/WDR1/KLF10/IFI16/IL20/BGLAP/SFRP1/GABPA/ADIPOQ/P4HTM/IL4/MYH9/TYROBP/DHRS2/ITGA2B/PURB/CLEC5A/ZFP36L1/TESC/PRKCB/FASN/TRAF6/PIP4K2A/STAT1/ARID4A/TNFSF11/WASF2/FOS/DLL1/SLC9B2/ZNF675/TGFB1/TMEM64/CDC42/CUL4A/POU4F1/JAK3/RARA/ZFPM1/LDB1/GATA3/TCTA/NME2/KAT6A/IL23A/SIRT1	130
BP	GO:1903555	regulation of tumor necrosis factor superfamily cytokine production	57/4749	163/18670	0.004148	0.04198	0.03415	TWIST1/CD86/IL10/ACP5/PTPN6/BCL3/TREX1/SIRPA/TIRAP/CLEC7A/GPNMB/LGALS9/HMGB1/ZFP36/TNFRSF8/CYBB/TLR4/LILRA2/FOXP3/CARD9/TSPO/CCR2/ARHGEF2/CCL3/CLU/HAVCR2/AXL/CD33/IRAK3/PTPRC/HLA-E/CD47/TLR2/NOD2/IL27RA/DEFB114/SYT11/NFKBIL1/CYBA/NLRC3/ZC3H12A/LILRA5/IFNGR1/GHRL/ADIPOQ/IL4/CD34/RIPK2/MAPKAPK2/TYROBP/DICER1/FZD5/DDT/RARA/PTAFR/CX3CR1/IL23A	57
BP	GO:0044088	regulation of vacuole organization	19/4749	42/18670	0.004178	0.04221	0.03434	TREX1/GRN/ANXA2P2/MTMR3/ANXA2/PIKFYVE/PINK1/ULK1/KIAA1324/UBQLN2/NPRL3/LRSAM1/NUPR1/PIP4K2A/RALB/PIP4K2B/PHF23/RAB1B/NPRL2	19
BP	GO:0046637	regulation of alpha-beta T cell differentiation	26/4749	63/18670	0.004258	0.04295	0.03495	CD86/IL18/NLRP3/CD83/CD80/IRF4/BCL6/CBFB/TNFSF4/LGALS9/PRDM1/HMGB1/FOXP3/IL4R/SMAD7/HLX/PNP/AP3D1/IL12RB1/ZC3H12A/RIPK2/JAK3/RARA/ZAP70/GATA3/IL23A	26
BP	GO:0046578	regulation of Ras protein signal transduction	79/4749	238/18670	0.004311	0.04333	0.03525	TIAM2/KIF14/NOTCH1/PLEKHG2/FOXM1/ARHGEF39/SQSTM1/SH2B2/ITGA3/KANK2/NTRK1/RAC1/ARHGEF40/BCL6/TIMP2/SGSM3/STAMBP/CSF1/ARHGEF18/FGD2/CDC42SE1/MCF2L2/CYTH2/PSD4/ARHGEF12/MAPRE2/ARHGEF5/TNFAIP1/TIAM1/ARHGEF2/F2RL2/MAPKAP1/ARRB1/ARHGAP35/STK19/RASGRF2/STMN3/GPR35/PREX1/PLEKHG1/EPS8L2/VAV2/STMN1/RASA3/PLEKHG7/ABCA1/FLOT1/P2RY10/CCDC125/IQSEC1/RASGRP4/PSD3/RAPGEF1/GBF1/RASA4/CRK/ECT2/MYO9B/RABGEF1/RASAL1/KCTD13/RALGPS1/F2R/LZTR1/OBSCN/CYTH1/CDC42SE2/ARF6/ARHGDIA/AKAP13/BCR/MCF2L/NET1/RTN4R/NUP62/IQSEC3/SHC1/SPATA13/ARHGEF26	79
BP	GO:0043966	histone H3 acetylation	25/4749	60/18670	0.004316	0.04333	0.03525	LIF/IRF4/SPI1/BRCA2/SMARCB1/CRTC2/NAP1L2/ING5/KAT2A/SUPT3H/TAF9B/TAF6L/TAF10/CHEK1/BRPF3/KAT6B/TADA2A/SPHK2/ZNF451/TRIM16/LDB1/GATA3/TADA1/KAT6A/SIRT1	25
BP	GO:0051784	negative regulation of nuclear division	25/4749	60/18670	0.004316	0.04333	0.03525	CENPF/LIF/AURKB/BUB1B/TTK/CDT1/TRIP13/CDC20/PTTG1/BUB1/FBXO43/PLK1/CCNB1/FBXO5/NDC80/TOM1L2/CHEK1/USP44/XRCC3/MAD2L2/KLHL22/APC/ATM/TOM1L1/DUSP1	25
BP	GO:0043433	negative regulation of DNA-binding transcription factor activity	59/4749	170/18670	0.004333	0.04344	0.03534	TWIST1/NLRP3/IL10/TRIB1/KLF4/PTGIS/TNFSF4/PTCH1/TNFRSF4/NFKBIE/CD200/FOXP3/SMAD7/PIM1/DAP/HMOX1/TONSL/TRAIP/ARRB1/GLIS2/HAVCR2/SRI/SFRP4/SETD6/FZD6/PKD2/BHLHE40/IRAK3/TCF7L2/SIGIRR/LRRC14/CYLD/TBX6/EZH2/CDKN2A/IRAK1/DDIT3/SUMO1/CHP1/ANXA4/NFKBIA/NFKBIL1/NLRC3/ZC3H12A/RLIM/BTRC/PIAS4/PRNP/ESR1/MAD2L2/NUPR1/CARD8/COMMD6/ZNF675/PSMD10/ID1/MXI1/COMMD7/SIRT1	59
BP	GO:0046330	positive regulation of JNK cascade	50/4749	140/18670	0.004342	0.04345	0.03535	IL1B/GADD45G/RASSF2/IL1RN/TIRAP/HMGB1/TNF/FGD2/TLR4/PTPN1/GADD45A/CARD9/MAP3K6/ARHGEF5/TIAM1/SDCBP/MAP3K2/DVL3/PAK1/RPS3/TNFRSF19/MAP3K5/STK3/NRK/DUSP22/NOD2/TRAF4/MAP3K11/TAOK3/WNT7A/TLR6/FZD8/MINK1/MAP2K4/FLT4/TRAF2/MAP4K1/ERN1/RIPK2/IL36A/TRAF6/BIRC7/TNFSF11/EDAR/FZD5/NCF1/MAP3K9/PLCB1/IL37/PJA2	50
BP	GO:0042063	gliogenesis	94/4749	290/18670	0.004347	0.04345	0.03535	EGR2/LIF/IL1B/NOTCH1/MBOAT7/TP73/CDK1/PPARG/DUSP10/ADORA2A/NTRK2/CSF1R/TTBK1/GRN/CNTF/GPC1/CDK5/CD9/NF2/ASCL1/TNF/CSF1/E2F1/SRGAP2/GSN/SKI/TLR4/CDKN2C/TNFRSF21/MTOR/LDLR/CNP/STAT3/TSPO/CCR2/PRDM8/ETV5/NKX2-1/FA2H/TIAM1/NAB2/CCL3/CLU/NTRK3/SUN2/EIF2B3/SPINT1/CCL2/PICK1/MPP5/NDRG1/PRKCI/EZH2/TLR2/VTN/SCRIB/SLC45A3/DRD1/LRP1/LTA/SOX8/FPR2/NAB1/ERCC2/ERBB2/ADAM22/NDN/WDR1/MMP24/DTX1/SOX11/VIM/PRPF19/POU3F1/B4GALT5/SIRT2/IFNGR1/S100A8/TNFRSF1B/C1QA/DICER1/P2RY1/HEXB/MBD1/MED12/DLL1/NKX6-2/TGFB1/MAPK1/HDAC10/SYNE2/CX3CR1/ILK/GCM1	94
BP	GO:0032680	regulation of tumor necrosis factor production	56/4749	160/18670	0.004368	0.04359	0.03546	TWIST1/IL10/ACP5/PTPN6/BCL3/TREX1/SIRPA/TIRAP/CLEC7A/GPNMB/LGALS9/HMGB1/ZFP36/TNFRSF8/CYBB/TLR4/LILRA2/FOXP3/CARD9/TSPO/CCR2/ARHGEF2/CCL3/CLU/HAVCR2/AXL/CD33/IRAK3/PTPRC/HLA-E/CD47/TLR2/NOD2/IL27RA/DEFB114/SYT11/NFKBIL1/CYBA/NLRC3/ZC3H12A/LILRA5/IFNGR1/GHRL/ADIPOQ/IL4/CD34/RIPK2/MAPKAPK2/TYROBP/DICER1/FZD5/DDT/RARA/PTAFR/CX3CR1/IL23A	56
BP	GO:0045599	negative regulation of fat cell differentiation	22/4749	51/18670	0.004375	0.04359	0.03546	TGFB1I1/TNF/E2F1/WNT10B/WWTR1/FOXO1/ZFP36L2/JAG1/INSIG1/ZADH2/ASXL1/DDIT3/BBS12/ARNTL/SIRT2/ADIPOQ/ANKRD26/TGFB1/ZFPM1/GATA3/TRIB3/SIRT1	22
BP	GO:0045577	regulation of B cell differentiation	14/4749	28/18670	0.004453	0.0443	0.03604	HMGB3/PTPN6/BTK/PPP2R3C/ZFP36L2/CYLD/NFAM1/IL7/SFRP1/CARD11/ZFP36L1/ATP11C/MIR17HG/BAD	14
BP	GO:0002827	positive regulation of T-helper 1 type immune response	11/4749	20/18670	0.004535	0.04505	0.03665	IL1B/IL18/IL1R1/CD80/CCR2/HLX/IL12RB1/IL27RA/IL18R1/RIPK2/IL23A	11
BP	GO:0032956	regulation of actin cytoskeleton organization	109/4749	343/18670	0.004569	0.04531	0.03686	CDC42EP4/SDC4/FSCN1/PLEKHG2/ICAM1/CIT/CSF1R/FES/PDGFA/HCK/RAC1/CYFIP1/CDK5/NF2/FHOD1/SNX9/CAPZB/GSN/CTTN/MTOR/MYADM/BAG4/CDC42EP1/SWAP70/TMOD2/TENM1/ARHGEF5/RHOG/CAPG/PAM/CORO1B/PTGER4/BST2/NTRK3/PDXP/TGFB3/WHAMMP3/PAK1/ADD3/PFN2/HIP1R/ARHGAP35/S1PR1/ARPC1B/PAK3/PREX1/PICK1/TMSB4Y/SPTBN1/CORO1A/STMN1/CLASP2/CD47/VASP/TRIOBP/TWF2/LIMCH1/CFL1/CDK10/COTL1/SPTAN1/S100A10/ARPC5/MKKS/LRP1/ARAP1/LIMK1/CAPZA1/SH3PXD2B/CRK/PRKCE/ECT2/ACTR3B/KANK3/WDR1/RHOF/ALMS1/RHOV/TMSB15A/RHOU/VILL/SFRP1/CD2AP/FER/BMP10/ARF6/TPM1/ARHGAP18/ARHGDIA/ARHGAP17/AKAP13/SORBS3/NTF3/WASF2/WHAMM/AP1AR/ID1/TGFB1/BCAS3/C15orf62/SEMA5A/CDC42/WAS/FMN1/ADD2/CCL27/MLST8/ILK/RAC3	109
BP	GO:0090263	positive regulation of canonical Wnt signaling pathway	52/4749	147/18670	0.004602	0.04556	0.03707	ZBED2/ASPM/WNK1/SULF2/GSKIP/LRRK1/UBE2B/WNT10B/GID8/SRC/PSMD8/VCP/SFRP4/PSMD1/PSMD2/PTK7/FGF9/RBPJ/PSMF1/TRPM4/TNKS2/PRDM15/PSMD9/PSMA5/FAM53B/FRAT1/PSMB7/RECK/PSMD5/ARNTL/YAP1/NRARP/TMEM198/PSME2/SFRP1/RSPO3/PSMB5/DLX5/FZD9/PSMB4/PSMA3/ZBED3/AXIN2/PSMD10/SEMA5A/PSMB1/PSMD7/CSNK1G2/PSMB3/PSMC5/ILK/PSMD11	52
BP	GO:0045926	negative regulation of growth	82/4749	249/18670	0.004664	0.04604	0.03746	GNG4/MAPK11/NOTCH1/PLAC8/TP73/CDKN1A/PPARG/DUSP10/BCL11A/BCL6/CDK5/ENO1/BBS2/SPP1/PTCH1/PPP2R1A/PML/SOCS2/SEMA4C/SEMA7A/ING1/HSPA1A/MT1E/CDKN2C/MT2A/NAIF1/PSRC1/MSX1/SEMA3G/ING5/FXN/NKD1/SEMA6C/BST2/PPT1/PAK1/SEMA6B/PTK6/MT1X/SMARCA4/FGF13/STK3/ARHGAP4/ADIPOR2/MT1H/PPP2CA/CDKN2A/ADIPOR1/WWC2/MT1G/CYP27B1/SH3BP4/SEMA3B/ADAM15/SEMA5B/GSK3A/CDKN2AIP/SFRP1/CRLF3/PTPRS/MT1A/DCBLD2/SEMA4D/BMP10/SPHK2/MT1B/EAF2/MT1M/IP6K2/PPP1R9B/PPARD/TGFB1/SEMA5A/NDUFA13/RTN4R/DNAJB2/MIR17HG/KCNK2/SESN2/MT1F/OSGIN2/SIRT1	82
BP	GO:0051321	meiotic cell cycle	82/4749	249/18670	0.004664	0.04604	0.03746	ESPL1/LIF/PKMYT1/ASPM/BUB1B/TTK/RBBP8/TOP2A/AURKA/HSPA2/TOP3A/EXO1/NEK2/TRIP13/CDC20/PTTG1/BUB1/CDC25A/NCAPD2/KIF18A/RAD54L/PPP2R1A/SMC3/SYCE3/NUF2/SLC2A8/MSH6/FBXO43/BRCA2/UBE2B/PLK1/CDC25C/RAD51/MSX1/TDRD9/CKS2/FBXO5/NUMA1/CDK2/DMC1/UBB/MND1/CCNE2/SUN2/TERF1/TUBGCP2/TAF1L/HELQ/FIGNL1/PPP2CA/TUBG2/NCAPH/REC8/STAG3/EME1/KLHDC3/SYCE2/SIRT2/MYH9/NCAPH2/TUBG1/UBR2/DMRTC2/ASZ1/PRKACB/ANKRD31/INSR/SMC1A/ATM/MLH3/PLCB1/NSUN2/RNF212/CDC25B/TUBGCP5/ERCC1/OSGIN2/PIWIL4/RAD54B/SPIN1/DUSP1/TUBGCP3	82
BP	GO:0009119	ribonucleoside metabolic process	37/4749	98/18670	0.004683	0.04615	0.03755	ACPP/APOBEC3H/GAMT/DHODH/TJP2/APOBEC3B/HPRT1/AK3/PNP/NME4/UPRT/MRI1/AICDA/NME3/ENPP4/MTRR/MTAP/AK4/MOCS1/APRT/IMPDH1/ENTPD4/LRGUK/RAB23/CARD11/GNMT/GUK1/AMPD3/ENOPH1/NT5E/CMPK1/CTPS2/UCK2/NFS1/NME9/NT5C2/NME2	37
BP	GO:0006839	mitochondrial transport	84/4749	256/18670	0.004711	0.04621	0.0376	PPIF/TP73/BNIP3L/YWHAH/YWHAE/TP63/YWHAZ/E2F1/HK2/SLC25A1/HSPA1A/NOL3/BAX/TIMM17A/SLC25A23/PMAIP1/NAIF1/DNAJC30/BAG4/GDAP1/CNP/STAT3/TSPO/USP36/TST/SAE1/MOAP1/MRPL18/SFN/BMF/TIMM10/CAMK2A/MICU1/BAP1/HIP1R/PDCD5/PARL/EYA2/NMT1/HPS4/BID/PRKAB2/PINK1/TIMM22/SLC25A14/TIMM50/ROMO1/SLC25A28/TFDP2/BAK1/GRPEL1/PRKAG2/YWHAQ/SLC25A5/STPG1/RAC2/ZNF205/BCL2L1/BAG3/IMMP1L/SLC25A36/GSK3A/RHOU/UBL5/MIPEP/CPT1A/RHOT2/FZD9/HSPA1L/ACACB/PAM16/TOMM22/AGK/FZD5/SFXN3/CHCHD4/MPC1/NDUFA13/SPG7/SLC25A16/TIMM9/SREBF2/BAD/MGARP	84
BP	GO:0009263	deoxyribonucleotide biosynthetic process	9/4749	15/18670	0.00474	0.04621	0.0376	TYMS/RRM2B/CMPK2/DTYMK/AK5/RRM1/DCTD/RRM2/GUK1	9
BP	GO:0032736	positive regulation of interleukin-13 production	9/4749	15/18670	0.00474	0.04621	0.0376	NLRP3/IRF4/TNFSF4/LGALS9/HLA-E/PAEP/IL4/RARA/GATA3	9
BP	GO:0034616	response to laminar fluid shear stress	9/4749	15/18670	0.00474	0.04621	0.0376	KLF2/KLF4/SMAD7/TGFB3/SMAD6/ABCA1/TGFB1/ADAM9/SREBF2	9
BP	GO:0048569	post-embryonic animal organ development	9/4749	15/18670	0.00474	0.04621	0.0376	MYO7A/VEGFA/KLF4/LDHA/MYO1E/BAX/BAK1/FZD5/ERCC1	9
BP	GO:1902187	negative regulation of viral release from host cell	9/4749	15/18670	0.00474	0.04621	0.0376	PML/TRIM25/TRIM26/TRIM13/MID2/TRIM35/CHMP3/TRIM15/TRIM5	9
BP	GO:1902969	mitotic DNA replication	9/4749	15/18670	0.00474	0.04621	0.0376	BCL6/MCM4/BRCA2/RAD51/MCM2/CDC45/GINS1/MCM3/CHEK2	9
BP	GO:0050792	regulation of viral process	70/4749	208/18670	0.00479	0.04663	0.03794	NOTCH1/TOP2A/CSF1R/IFIT1/ISG15/ANXA2P2/LGALS9/APOBEC3H/PML/SMC3/CHMP2B/KPNA2/MX1/TNF/ZFP36/GSN/TRIM25/ANXA2/TRIM26/SMARCB1/IFIT5/RSAD2/SNF8/FCN1/IFITM2/PPIH/TRIM62/CCL3/BST2/MORC2/CD74/OASL/LGALS1/ISG20/SMARCA4/TBC1D20/CFL1/TRIM13/BANF1/SP1/IFITM3/AICDA/IFITM1/POLR2I/MID2/JUN/FMR1/TAF11/CCNK/RAD23A/ZNF639/POLR2C/ZC3H12A/OAS1/CNOT7/IFI16/ILF3/ZC3HAV1/CHMP2A/STAU1/POLR2J/TRIM35/STAT1/STOM/NUCKS1/POLR2A/SETDB1/CHMP3/TRIM15/TRIM5	70
BP	GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II	15/4749	31/18670	0.004866	0.0473	0.03848	IL10/SRF/SPI1/STAT3/NR3C1/SMAD6/SMARCA4/ATOH8/GNL3/JUN/SMAD1/FOS/TGFB1/PDGFB/SREBF2	15
BP	GO:0046718	viral entry into host cell	44/4749	121/18670	0.004928	0.04784	0.03892	CD86/ANPEP/CDK1/TYRO3/ITGA2/ICAM1/SLC1A5/CD80/MRC1/HAVCR1/TFRC/LGALS9/TNFRSF4/GSN/HSPA1A/TRIM25/LDLR/TRIM26/HYAL3/FCN1/IFITM2/TRIM62/SLC52A1/HTR2A/AXL/CD74/NUP153/CCR5/CTSB/CLEC4G/LGALS1/SLC52A2/IFITM3/IFITM1/CD46/MID2/CR2/KPNA3/ZNF639/UVRAG/RPSA/LAMP1/CLEC5A/TRIM5	44
BP	GO:0043627	response to estrogen	29/4749	73/18670	0.005063	0.04907	0.03992	PPARG/ARID5A/LDHA/TRIM25/IL4R/DTYMK/HMOX1/TGFB3/SMAD6/ARPC1B/GBA/WNT7A/CYP27B1/CA2/CITED2/KRT19/CTNNA1/SFR1/BGLAP/SFRP1/GHRL/TNFRSF11B/ESR1/BCAS3/RARA/MAPK1/CCND1/SRA1/GATA3	29
BP	GO:0006888	ER to Golgi vesicle-mediated transport	71/4749	212/18670	0.005159	0.04992	0.04061	SEC13/YIPF5/RAB33A/GORASP1/SEC24D/CAPZB/CREB3L2/MCFD2/CTAGE4/PROS1/ANK1/PROC/F5/RANGRF/SORL1/STX5/SEC16A/SEC22C/KDELR2/VCP/CNIH2/WHAMMP3/COG8/DCTN5/RAB19/COG7/TMED3/ANKRD28/SPTBN1/BCAP31/TBC1D20/SPTAN1/LMF1/COPE/INSIG1/TMED9/COG1/NRBP1/TMEM115/CAPZA1/GBF1/TMED10/CTSZ/TMED5/LMAN2/CTAGE9/TMED4/YIF1A/ARF4/BGLAP/YIF1B/VTI1B/ACTR1A/COG3/RNF139/GOPC/TRAPPC4/RAB1A/SEC22A/WHAMM/PROZ/PPP6C/TMED1/COPG2/TMED6/TRAPPC12/PEF1/PPP6R1/RAB1B/RAB12/USO1	71
BP	GO:1990266	neutrophil migration	43/4749	118/18670	0.005169	0.04992	0.04061	CXCL13/IL1B/IL1R1/CCL20/CCL3L3/RAC1/IL1RN/CSF3R/CCL22/TIRAP/DAPK2/LGALS3/CXCL10/PDE4D/CCL3/PDE4B/CD74/CD177/CCL2/PREX1/CCL17/ITGA1/CCL18/CXCL9/CXCL2/CXCL3/GBF1/C3AR1/RAC2/WDR1/CD99L2/S100A8/CKLF/UMOD/IL36A/C1QBP/CCL23/CCL7/PPBP/THBS4/CCL15/IL37/IL23A	43
BP	GO:0043368	positive T cell selection	16/4749	34/18670	0.005191	0.04992	0.04061	BATF/SRF/IRF4/MTOR/FOXP3/STAT3/CD74/LY9/PTPRC/CYLD/IL12RB1/CD3E/THEMIS/ZAP70/ZFPM1/IL23A	16
BP	GO:0002821	positive regulation of adaptive immune response	39/4749	105/18670	0.005197	0.04992	0.04061	IL1B/CD1E/IL18/NLRP3/IL1R1/CD80/TNFSF4/TFRC/TNF/CD1A/FOXP3/CD1C/RSAD2/CCR2/HLA-H/HLA-G/TP53BP1/BTK/CD1B/CD1D/HLX/PTPRC/HLA-E/IL12RB1/IL27RA/LTA/IL18R1/TRAF2/TNFSF13/IL4/RIPK2/MAD2L2/TRAF6/FZD5/TGFB1/GATA3/P2RX7/IL23A/SIRT1	39
BP	GO:0045185	maintenance of protein location	39/4749	105/18670	0.005197	0.04992	0.04061	IL10/BCL3/HK1/CDK5/PML/HSPA5/HK2/GSN/NFKBIE/DAND5/TSPO/SORL1/TONSL/KDELR2/SRI/PKD2/SUN2/TMSB4Y/PINK1/EZR/TWF2/INSIG1/SPAG4/PARK7/TOPORS/NFKBIA/NFKBIL1/SRGN/SYNE3/TMSB15A/ARL2BP/GOPC/VPS13D/ARL2/CER1/PSMD10/MXI1/SYNE2/BARD1	39
BP	GO:1902750	negative regulation of cell cycle G2/M phase transition	39/4749	105/18670	0.005197	0.04992	0.04061	AURKB/TICRR/CDK1/DTL/AURKA/CLSPN/CDC6/ATF5/PLK1/PSMD8/PSMD1/PSMD2/ORC1/TOPBP1/PSMF1/PSMD9/PSMA5/TAOK3/BRCC3/PSMB7/CHEK1/GPR132/PSMD5/MIIP/ZNF830/PSME2/PSMB5/CDC14B/NAE1/PSMB4/PSMA3/ATM/PSMD10/PSMB1/PSMD7/PSMB3/SYF2/PSMC5/PSMD11	39
BP	GO:0001906	cell killing	58/4749	168/18670	0.005275	0.05059	0.04115	CD1E/IL18/IL21/ICAM1/PTPN6/GAPDH/CTSH/CLEC7A/CEACAM1/LGALS9/ULBP2/CD1A/RAET1E/CD1C/TUBB/RIPK3/HLA-H/RPL30/HLA-G/SH2D1A/CD1B/HAVCR2/LYZ/TUBB4B/HPRT1/CD1D/PGLYRP3/PTPRC/RPS19/CORO1A/HLA-E/ROMO1/MICA/IL12RB1/HMGN2/LCE3C/ARG1/LAG3/CADM1/RAB27A/UNC13D/CRK/IL7R/HTN3/IL13/APOL1/LAMP1/IL4/ULBP1/TYROBP/DEFA1B/KRT6A/DEFA4/KLRK1/P2RX7/PRDX1/BAD/IL23A	58
BP	GO:0009067	aspartate family amino acid biosynthetic process	12/4749	23/18670	0.00538	0.05129	0.04173	ASNS/MRI1/MTHFD1/BHMT/MTRR/MTAP/ENOPH1/AASDHPPT/MTR/PLOD3/ASNSD1/BHMT2	12
BP	GO:0032753	positive regulation of interleukin-4 production	12/4749	23/18670	0.00538	0.05129	0.04173	CD86/NLRP3/IRF4/TNFSF4/LGALS9/FOXP3/HAVCR2/HLA-E/CEBPB/CD3E/RARA/GATA3	12
BP	GO:0051043	regulation of membrane protein ectodomain proteolysis	12/4749	23/18670	0.00538	0.05129	0.04173	IL1B/FURIN/IL10/TIMP4/TIMP2/SNX9/TNF/TIMP1/SNX33/TNFRSF1B/TIMP3/ADAM9	12
BP	GO:0071294	cellular response to zinc ion	12/4749	23/18670	0.00538	0.05129	0.04173	MT1E/MT2A/TSPO/ATP13A2/MT1X/MT1H/HVCN1/MT1G/MT1A/MT1B/MT1M/MT1F	12
BP	GO:0035335	peptidyl-tyrosine dephosphorylation	38/4749	102/18670	0.005433	0.05157	0.04196	PTPN13/DUSP10/DUSP4/CDKN3/PTPRF/PTPN6/DUSP6/PTPN7/CDC25A/MTMR3/PTPN1/CDC25C/PTPN14/DUSP5/PALD1/PTPN4/PTPN9/EYA2/DUSP16/PTPRC/TIMM50/DUSP23/DUSP22/PTPN18/DNAJC6/PTPRM/PTPMT1/MTMR14/DUSP18/DUPD1/CDC14B/PTPRS/SSH2/ACP1/DUSP14/CDC25B/PTP4A3/DUSP1	38
BP	GO:0006270	DNA replication initiation	17/4749	37/18670	0.005436	0.05157	0.04196	TICRR/CDT1/MCM4/MCM5/CDC6/MCM10/MCM2/CDC45/CDK2/ORC1/CCNE2/MCM7/POLE/MCM3/ORC2/LRWD1/POLE2	17
BP	GO:0060236	regulation of mitotic spindle organization	17/4749	37/18670	0.005436	0.05157	0.04196	GPSM2/TPX2/TACC3/SMC3/CHMP2B/HSPA1A/PLK1/FSD1/PSRC1/NUMA1/RAE1/CHMP1A/CHMP2A/SMC1A/MAP9/CEP97/NUP62	17
BP	GO:0006006	glucose metabolic process	70/4749	209/18670	0.005442	0.05157	0.04196	TPI1/PHLDA2/IGFBP4/GAPDH/HK1/ENO1/PGAM1/PFKP/ATF3/GPI/TNF/PPP1CB/HK2/SLC25A1/BRAT1/PMAIP1/MTOR/SDS/CRTC2/SRC/PGM2L1/PKM/FABP5/ALDOC/PDHB/CRY1/KAT2A/ATF4/PER2/IGFBP3/FOXO1/MDH2/RORC/PFKFB2/SLC45A3/DLAT/ADIPOR1/ENO3/MAEA/PPP1R3E/C1QTNF3/TFAP2B/EPM2AIP1/GALM/OAS1/GSK3A/PHKG2/ALDOA/GHRL/GNMT/ADIPOQ/CPT1A/DGAT2/SERP1/ACACB/INSR/SLC35B4/PFKL/ALDOB/PPARD/ALDH5A1/CLK2/COX11/OMA1/SESN2/AKR1A1/PDX1/BAD/PPP1R3B/SIRT1	70
BP	GO:0044272	sulfur compound biosynthetic process	65/4749	192/18670	0.005491	0.05196	0.04227	CHAC1/PDPR/CHST15/SLC25A1/CHPF2/TPK1/TECR/MPST/CHAC2/SCD/GGT1/OGN/CSGALNACT1/PDHB/PPT1/SLC35D2/ACSL1/PDHX/SLC35D1/CTH/OPLAH/GSTO1/B3GALT6/HSD17B8/LIAS/MRI1/B3GNT2/SLC35B2/CHST7/MTHFD1/BHMT/DLAT/GGTLC2/SP1/ELOVL7/MTRR/MTAP/DSEL/ST3GAL3/GSTM1/ELOVL1/ACSL4/CHPF/METTL16/B4GALT5/GSTT1/ENOPH1/MGST2/ACACB/GCLC/GGT7/ACSS1/FASN/MTR/CHST13/MGST3/GSTK1/PAPSS2/GSS/XYLT1/MPC1/GSTZ1/B4GALT4/AKR1A1/BHMT2	65
BP	GO:0022604	regulation of cell morphogenesis	148/4749	484/18670	0.005586	0.05277	0.04293	CDC42EP4/SKIL/VEGFA/ICAM1/MAP6/NTRK2/NEDD9/CSF1R/SIPA1L1/LARP4/FES/SRF/HCK/RAC1/BCL11A/PLXNB2/CYFIP1/LZTS1/YWHAH/CDK5/CORO1C/SPP1/GORASP1/SEMA4C/PLXNB1/TNFRSF12A/CAPZB/MYH10/ARHGEF18/LRP8/SEMA7A/FGD2/ZSWIM5/CTTN/CDC42SE1/S100A13/CUX1/MYADM/ZFYVE27/CDC42EP1/SEMA3G/SRC/FITM2/RHOG/TIAM1/LIMD1/SYT4/SEMA6C/CORO1B/ZMYM1/CCL3/AMIGO1/DOCK1/NTRK3/DVL3/SDC2/PLXNA1/PAK1/LIMS1/FMNL1/CPNE5/SEMA6B/DOCK5/ARHGAP35/CCL2/PAK3/PREX1/PHIP/FBXO31/SMURF1/LRP4/FGF13/EZR/CORO1A/WDPCP/ARHGAP4/TRIOBP/ZMYM6/TWF2/L1CAM/CFL1/PLXND1/PARVB/ACTN4/DVL1/S100A10/LRP1/ARAP1/LIMK1/THY1/ZSWIM6/TTL/WNT7A/ARHGAP15/UNC13D/STK25/FMR1/UBE3A/CD44/CRK/ATP10A/ARHGAP33/WDR1/SEMA3B/IST1/RHOF/SEMA5B/RASAL1/BRSK2/RHOV/RAPGEF2/SYNE3/SHROOM3/CHN1/RHOU/ALDOA/MYH9/PARP6/PTPRS/EPB41/CHRNA3/P2RY1/CDC42SE2/FAM171A1/SEMA4D/C1QBP/HEXB/TPM1/ARHGAP18/LRRC4C/ARHGDIA/NEFL/CCL7/AP1AR/ID1/RUFY3/C15orf62/SEMA5A/CDC42/HAS2/RTN4R/ADNP/TRPC5/GDI1/FYN/DLG4/ILK/RAC3	148
BP	GO:0002369	T cell cytokine production	18/4749	40/18670	0.005611	0.05278	0.04294	IL1B/IL18/NLRP3/IL1R1/TNFSF4/FOXP3/RSAD2/SMAD7/CCR2/TRPM4/ARG1/IL18R1/TRAF2/IL4/TNFRSF1B/TRAF6/FZD5/GATA3	18
BP	GO:0006734	NADH metabolic process	18/4749	40/18670	0.005611	0.05278	0.04294	TPI1/GAPDH/HK1/ENO1/PGAM1/PFKP/GPI/HK2/PGM2L1/PKM/ALDOC/VCP/MDH2/ENO3/NUDT17/ALDOA/PFKL/ALDOB	18
BP	GO:0032467	positive regulation of cytokinesis	18/4749	40/18670	0.005611	0.05278	0.04294	AURKB/KIF14/KIF23/CIT/KIF20B/RACGAP1/CDC6/SVIL/PKP4/PRKCE/ECT2/CDC14B/CENPV/CDC42/CDC25B/CXCR5/NUP62/TAS2R13	18
BP	GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors	24/4749	58/18670	0.005668	0.05324	0.04331	SKIL/ICAM1/FAIM2/RFFL/LGALS3/ATF3/SERPINE1/PEA15/PMAIP1/GPX1/HMOX1/ARHGEF2/TMC8/CFLAR/FAS/TNFRSF10B/STK3/FEM1B/PARK7/BCL2L1/SFRP1/TRAF2/TNFSF10/TIMP3	24
BP	GO:0048145	regulation of fibroblast proliferation	32/4749	83/18670	0.005703	0.05349	0.04352	CDKN1A/PPARG/PDGFA/CCNA2/ANXA2P2/CDC6/PML/SIRT6/E2F1/SKI/BAX/ANXA2/CCNB1/CD74/S100A6/TP53INP1/LTA/FOSL2/EMD/JUN/PEX2/FTH1/NLRC3/IL13/SFRP1/ESR1/NUPR1/TGFB1/BMI1/PDGFB/B4GALT7/FBXO4	32
BP	GO:0010824	regulation of centrosome duplication	19/4749	43/18670	0.005725	0.05354	0.04356	CCNF/STIL/PLK4/CHMP2B/PLK2/CENPJ/KAT2A/POC1A/NUBP1/MDM1/CHORDC1/C10orf90/ALMS1/XRCC3/CHMP1A/TMEM67/CHMP2A/NUP62/CHMP3	19
BP	GO:0034198	cellular response to amino acid starvation	19/4749	43/18670	0.005725	0.05354	0.04356	CDKN1A/ATF3/MAP1LC3A/MTOR/ITFG2/DAP/ATF4/FAS/MAP3K5/WDR24/C12orf66/SLC38A2/NPRL3/EIF2AK3/RRAGB/MAPK1/SESN2/SEH1L/NPRL2	19
BP	GO:0032874	positive regulation of stress-activated MAPK cascade	59/4749	172/18670	0.005762	0.05381	0.04377	IL1B/VEGFA/GADD45G/RASSF2/IL1RN/TIRAP/SEMA4C/HMGB1/TNF/FGD2/TLR4/PTPN1/GADD45A/CARD9/MAP3K6/ARHGEF5/TIAM1/SDCBP/MAP3K2/DVL3/PAK1/RPS3/TNFRSF19/MAP3K5/STK3/NRK/DUSP22/NOD2/TRAF4/MAP3K11/MID1/IL26/TAOK3/WNT7A/TLR6/FZD8/STK25/MAP3K3/ZC3H12A/MINK1/MAP2K4/FLT4/EMC10/TRAF2/MAP4K1/ERN1/RIPK2/IL36A/TRAF6/BIRC7/MIR181D/TNFSF11/EDAR/FZD5/NCF1/MAP3K9/PLCB1/IL37/PJA2	59
BP	GO:1990928	response to amino acid starvation	20/4749	46/18670	0.005788	0.05391	0.04386	CDKN1A/ATF3/EIF4EBP1/MAP1LC3A/MTOR/ITFG2/DAP/ATF4/FAS/MAP3K5/WDR24/C12orf66/SLC38A2/NPRL3/EIF2AK3/RRAGB/MAPK1/SESN2/SEH1L/NPRL2	20
BP	GO:0031529	ruffle organization	22/4749	52/18670	0.00579	0.05391	0.04386	ICAM1/CSF1R/RAC1/CYFIP1/CORO1C/MTOR/BAG4/PLEKHA1/RHOG/CORO1B/SH3YL1/PFN2/EPS8L2/WDPCP/AIF1/PLEKHM1/ARF6/TPM1/AIF1L/PIP5K1A/USP17L2/ARHGEF26	22
BP	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	21/4749	49/18670	0.005808	0.054	0.04393	G0S2/SKIL/ATF3/PPP2R1A/PML/TNFRSF12A/PEA15/PMAIP1/BID/PTPRC/CYLD/STK3/WWOX/TNFSF12/CTNNA1/SFRP1/TRAF2/TNFSF10/ITM2C/TIMP3/PAK2	21
BP	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	47/4749	132/18670	0.00593	0.05496	0.04471	GRAMD4/PPARG/NLRP3/CASP9/CTSH/CLEC7A/HIP1/LGALS9/PML/HMGB1/TNF/GSN/BAX/PMAIP1/CARD9/DAP/P2RX1/ARRB1/VCP/BCL2L13/RPS3/HIP1R/PDCD5/CCK/FAS/BID/TNFRSF10B/MAP3K5/BCAP31/KHDC1/BAK1/CTSD/CASP8AP2/ACVR1C/ACER2/DAPK1/TRAF2/EIF2AK3/S100A8/ST18/F3/F2R/TNFSF10/CARD8/NDUFA13/BAD/SIRT1	47
BP	GO:0045598	regulation of fat cell differentiation	47/4749	132/18670	0.00593	0.05496	0.04471	PPARG/DUSP10/ZNF385A/TGFB1I1/SYAP1/TNF/ZFP36/E2F1/ZBTB7C/MTOR/WNT10B/ASXL2/HTR2A/WWTR1/PRDM16/FOXO1/ZFP36L2/JAG1/RORC/CARM1/STK3/TRPM4/INSIG1/ZADH2/ASXL1/DDIT3/SH3PXD2B/BBS12/CEBPB/ARNTL/ZC3H12A/TPH1/CREBL2/RARRES2/SFRP1/SIRT2/ADIPOQ/ANKRD26/ZFP36L1/PPARD/TGFB1/METRNL/TMEM64/ZFPM1/GATA3/TRIB3/SIRT1	47
BP	GO:0007568	aging	102/4749	321/18670	0.005937	0.05496	0.04471	TWIST1/AURKB/FOXM1/CDK1/CDKN1A/ICAM1/CASP9/CD68/IL10/CDKN2B/NTRK1/SRF/BCL6/TREX1/TIMP2/TP63/RAD54L/PML/TYMS/NFKB2/MSH6/GSN/PLK2/BRCA2/AKT3/SERPINE1/MTOR/LMNA/CNP/STAT3/VASH1/PDCD4/TSPO/NUDT1/FBXO5/SLC12A2/MBD2/ABAT/HLA-G/PDE4D/HTR2A/TGFB3/LIMS1/NQO1/DNAJA3/KCNMB1/CARM1/NAMPT/ROMO1/BCL2A1/LITAF/BAK1/CDKN2A/LRP1/IRAK1/ENO3/ARG1/SIRT3/GPX4/CNR1/JUN/BCL2L12/ERCC2/TIMP1/CHEK1/MPO/ARNTL/MAP3K3/CTNNA1/SERPING1/YPEL3/BGLAP/ADM/ALDH3A1/PRNP/TNFRSF1B/C1QA/SERP1/CANX/GCLC/ATR/CHEK2/P2RY1/MBD1/FOS/GSS/OGG1/ATM/WRN/SMC5/ATG7/TGFB1/MAPK1/NUP62/PDX1/ERCC1/FBXO4/KAT6A/ILK/MAGEA2B/TERF2/SIRT1	102
BP	GO:0030177	positive regulation of Wnt signaling pathway	61/4749	179/18670	0.005945	0.05496	0.04471	ZBED2/ASPM/WNK1/SULF2/GSKIP/DEPDC1B/LRRK1/SKI/UBE2B/WNT10B/GID8/SRC/NKD1/MBD2/PSMD8/VCP/SFRP4/PSMD1/PSMD2/PTK7/FGF9/RBPJ/PSMF1/ATP6V0C/SMARCA4/TRPM4/TLR2/TNKS2/PRDM15/PSMD9/PSMA5/FAM53B/FRAT1/PSMB7/RECK/PSMD5/ARNTL/YAP1/NRARP/TMEM198/PSME2/SFRP1/RSPO3/PSMB5/DLX5/MLLT3/FZD9/PSMB4/PSMA3/ZBED3/AXIN2/PSMD10/SEMA5A/PSMB1/PSMD7/CSNK1G2/PSMB3/PSMC5/ILK/SPIN1/PSMD11	61
BP	GO:0051261	protein depolymerization	40/4749	109/18670	0.005956	0.05498	0.04473	KIF2C/MICAL1/KIF24/KIF18A/CAPZB/GSN/CKAP2/ASPH/MICAL2/SWAP70/TMOD2/CAPG/ARHGEF2/PDXP/ADD3/SH3GL1/STMN3/SPTBN1/FGF13/STMN1/CLASP2/TRIOBP/TWF2/CFL1/SPTAN1/MID1/CAPZA1/MAP1S/DNAJC6/TRIM54/WDR1/MICAL3/VILL/MAP1A/APC/SEMA5A/NCKAP5/KIF19/ADD2/CKAP5	40
BP	GO:0060706	cell differentiation involved in embryonic placenta development	13/4749	26/18670	0.006072	0.05577	0.04537	LIF/E2F7/E2F8/PRDM1/PLK4/ST14/SOCS3/SNAI1/STK3/KRT19/DNAJB6/FZD5/GCM1	13
BP	GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	13/4749	26/18670	0.006072	0.05577	0.04537	TP73/YWHAH/YWHAE/TP63/YWHAZ/E2F1/PMAIP1/SFN/NMT1/BID/TFDP2/YWHAQ/BAD	13
BP	GO:1900740	positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	13/4749	26/18670	0.006072	0.05577	0.04537	TP73/YWHAH/YWHAE/TP63/YWHAZ/E2F1/PMAIP1/SFN/NMT1/BID/TFDP2/YWHAQ/BAD	13
BP	GO:0051100	negative regulation of binding	58/4749	169/18670	0.006076	0.05577	0.04537	CRMP1/AURKB/AURKA/GPSM1/PTPRF/IL10/IFIT1/NEK2/TTBK1/CAMK1/HSPA5/E2F1/BAX/MSX1/SORL1/HMOX1/TMC8/PIM2/SRI/SUMO3/ENHO/PER2/CARM1/ZNF304/LRPAP1/STMN1/TFIP11/DVL1/DTNBP1/DDIT3/SUMO1/PARK7/JUN/EPB41L5/NFKBIA/CTSZ/SOX11/ADAM15/IFI16/BTAF1/BAG2/DDX11/CFHR1/ADIPOQ/MAD2L2/P2RY1/CCL23/CYP2D6/IFIT2/RALB/ZNF675/MITD1/ID1/ADNP/DNAJB2/PDGFB/ZFPM1/ACTB	58
BP	GO:0016575	histone deacetylation	30/4749	77/18670	0.006126	0.05615	0.04568	VEGFA/RCOR1/BCL6/SFPQ/ZNHIT1/SIRT6/SKI/FOXP3/MORF4L2/PER2/ELK4/PINK1/SIRT3/MIER2/C6orf89/SAP30L/SIRT2/CAMK2D/KDM5A/BAZ2A/SPHK2/MTA1/CTBP1/HDAC9/MTA3/SIRT7/TGFB1/HDAC10/USP17L2/SIRT1	30
BP	GO:0097529	myeloid leukocyte migration	70/4749	210/18670	0.006169	0.05646	0.04593	CXCL13/IL1B/VEGFA/IL1R1/CCL20/CCL3L3/RAC1/IL17A/IL1RN/CSF3R/SIRPA/CCL22/TIRAP/CCR1/DAPK2/LGALS3/CD9/HMGB1/CSF1/CD200/CXCL10/SERPINE1/SWAP70/CCR2/ARHGEF5/PDE4D/CCL3/PTGER4/PDE4B/CD74/CD177/CCL2/PREX1/CCL17/RPS19/ITGA1/CD47/AIF1/CCL18/CXCL9/FLT1/CXCL2/CXCL3/FPR2/GBF1/C3AR1/IL17RC/RAC2/WDR1/CD99L2/RARRES2/S100A8/CKLF/UMOD/IL36A/C1QBP/CCL23/TNFSF11/CCL7/PPBP/THBS4/DDT/PLCB1/CCL15/PDGFB/CX3CR1/VEGFC/IL37/IL23A/DUSP1	70
BP	GO:0060348	bone development	72/4749	217/18670	0.006267	0.05727	0.04659	TWIST1/SULF2/ACP5/SRF/TRIM45/PTPN6/ZNF385A/ANXA2P2/COL6A2/PLXNB1/LRRK1/SKI/ANXA2/DCHS1/MSX1/VKORC1/SRC/NAB2/CSGALNACT1/GNAS/PTGER4/SFRP4/TGFB3/POC1A/COL6A1/PHEX/FAM20C/RUNX2/CARM1/TIFAB/PTPRC/MEF2D/PRPSAP2/SBDS/INSIG1/IFT172/ASXL1/NAB1/SH3PXD2B/LRP5L/BGLAP/SMAD1/RAB23/GHRL/IFT80/BBX/PAX1/POR/DLX5/TYROBP/LRP6/HOXA11/SEMA4D/MBTPS2/FGF8/PIP4K2A/AKAP13/AXIN2/TMEM119/PAPSS2/TNFSF11/WASF2/MCPH1/XYLT1/SLC9B2/CER1/TGFB1/HAS2/RARA/ZFPM1/DHRS3/ANKRD11	72
BP	GO:0000212	meiotic spindle organization	8/4749	13/18670	0.006314	0.05745	0.04674	ESPL1/ASPM/AURKA/PPP2R1A/FBXO5/TUBG2/MYH9/TUBG1	8
BP	GO:0051315	attachment of mitotic spindle microtubules to kinetochore	8/4749	13/18670	0.006314	0.05745	0.04674	KIF2C/CDT1/NUF2/CENPE/NDC80/BOD1/CHAMP1/SEH1L	8
BP	GO:0071352	cellular response to interleukin-2	8/4749	13/18670	0.006314	0.05745	0.04674	IL2RA/IL2RB/IL2RG/CDC5L/STAT5A/JAK3/SHC1/JAK1	8
BP	GO:0001101	response to acid chemical	108/4749	343/18670	0.006439	0.05848	0.04758	EGR1/VEGFA/PPARG/ITGA2/ICAM1/KLF2/NTRK2/NTRK1/KLF4/BCL11A/CTSH/TNFSF4/PTCH1/CD9/TYMS/ASCL1/TNF/DHODH/E2F1/GSN/CYBB/COL18A1/MTOR/LDLR/WNT10B/GDAP1/LANCL2/FFAR2/CCNB1/SRC/SCD/GLDC/PTGER4/AMIGO1/NTRK3/PTK7/HMGCL/ADCY6/PKD2/ASNS/COL6A1/ACSL1/FFAR3/NQO1/FOXO1/PTK6/DHFR/AQP2/KCNMB1/PINK1/TWF2/CFL1/TLR2/ABCA1/ATP2B4/ASXL1/ARG1/RXRA/SLC38A9/PPP5C/SH3BP4/ABCB4/SLC10A3/PRKCE/CEBPB/PTGER2/ACER2/BCL2L1/CYBA/ZC3H12A/YAP1/SFRP1/PIK3C3/ADIPOQ/CPT1A/LTK/DGAT2/AANAT/UBR2/LAMTOR4/GCLC/TESC/CPEB1/LAMTOR2/KLHL22/TIE1/GSS/OGG1/ATM/RRAGB/FFAR1/ATG7/CLK2/NDUFA13/MGMT/RARA/PDGFB/TRIM16/LRP11/SESN2/PTAFR/PDX1/GIPR/BAD/FYN/NME2/CRLS1/DUSP1	108
BP	GO:0043487	regulation of RNA stability	62/4749	183/18670	0.006447	0.05848	0.04758	TIRAP/YWHAZ/SERBP1/ZFP36/E2F1/HSPA1A/ZC3H12D/PLEKHN1/MTOR/PSMD8/HNRNPA0/UBB/PSMD1/PSMD2/PSMF1/CIRBP/UPF1/RPS27A/ZFP36L2/PRKCA/ALKBH5/RBM46/UBA52/MEX3D/PSMD9/PSMA5/RBM23/FMR1/PSMB7/EXOSC2/PSMD5/ZC3H12A/VIM/PSME2/ELAVL1/CSDC2/YTHDF3/FASTKD3/METTL16/TNFSF13/SAMD4B/GIGYF2/PSMB5/RBM38/TNFRSF1B/MAPKAPK2/YBX1/SMG6/ZFP36L1/PSMB4/PSMA3/TBRG4/AXIN2/PSMD10/PSMB1/PSMD7/PSMB3/PSMC5/TNPO1/KHSRP/EXOSC9/PSMD11	62
BP	GO:0046849	bone remodeling	34/4749	90/18670	0.006454	0.05848	0.04758	NCDN/CSF1R/ACP5/RASSF2/RAC1/TFRC/SPP1/LRRK1/TPP1/SRC/PPARGC1B/CTHRC1/TGFB3/RAB3D/S1PR1/PRKCA/PLEKHM1/CA2/RAC2/LRP5L/TPH1/IL7/BGLAP/SFRP1/TNFRSF11B/SUCO/LRP6/TRAF6/TMEM119/TNFSF11/ZNF675/TGFB1/TMEM64/P2RX7	34
BP	GO:0032091	negative regulation of protein binding	38/4749	103/18670	0.006536	0.05914	0.04811	CRMP1/AURKB/AURKA/GPSM1/PTPRF/IL10/IFIT1/TTBK1/CAMK1/HSPA5/BAX/SORL1/TMC8/PIM2/CARM1/LRPAP1/STMN1/TFIP11/DVL1/DTNBP1/PARK7/EPB41L5/CTSZ/ADAM15/BAG2/DDX11/CFHR1/ADIPOQ/CCL23/IFIT2/RALB/MITD1/ID1/ADNP/DNAJB2/PDGFB/ZFPM1/ACTB	38
BP	GO:0006364	rRNA processing	71/4749	214/18670	0.006613	0.05963	0.04851	RPS8/RPL10A/RPS27/RPL35/USP36/NUDT16/XRN2/RPL5/RPL26/RPS6/RPS15/RRP1/MRPS11/RPL7/NSUN4/NOP10/ISG20/DDX27/NOL9/BYSL/POP5/RPS19/NSUN5P1/PA2G4/ERI3/FAM207A/RIOK1/RPS16/SART1/SBDS/RPS9/RPL14/NOLC1/YBEY/DDX17/ZNHIT3/NOP14/EXOSC2/TRMT112/NPM3/DDX54/UTP20/EMG1/BOP1/UTP23/BTRC/FBL/FDXACB1/RRNAD1/METTL16/WDR12/ABT1/TEX10/RPS28/ZCCHC4/RPL7A/MRTO4/ESF1/MDN1/URB1/RRP8/RPP30/RPL11/RPF1/GTF2H5/RCL1/UTP3/TFB2M/NGDN/EXOSC9/SIRT1	71
BP	GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	59/4749	173/18670	0.006616	0.05963	0.04851	IL1B/VEGFA/GADD45G/RASSF2/IL1RN/TIRAP/SEMA4C/HMGB1/TNF/FGD2/TLR4/PTPN1/GADD45A/CARD9/MAP3K6/ARHGEF5/TIAM1/SDCBP/MAP3K2/DVL3/PAK1/RPS3/TNFRSF19/MAP3K5/STK3/NRK/DUSP22/NOD2/TRAF4/MAP3K11/MID1/IL26/TAOK3/WNT7A/TLR6/FZD8/STK25/MAP3K3/ZC3H12A/MINK1/MAP2K4/FLT4/EMC10/TRAF2/MAP4K1/ERN1/RIPK2/IL36A/TRAF6/BIRC7/MIR181D/TNFSF11/EDAR/FZD5/NCF1/MAP3K9/PLCB1/IL37/PJA2	59
BP	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	14/4749	29/18670	0.006619	0.05963	0.04851	E2F7/CDT1/CDC6/TYMS/E2F1/FBXO5/CDC45/ORC1/DHFR/BRD4/TFDP2/RRM2/NPAT/BACH1	14
BP	GO:0001892	embryonic placenta development	33/4749	87/18670	0.006727	0.06044	0.04917	LIF/E2F7/E2F8/CSF2/IL10/PHLDA2/PLCD3/PRDM1/PLK4/ST14/VASH1/SOCS3/SNAI1/RBPJ/PKD2/SPINT1/STK3/PCDH12/NRK/GGNBP2/HS6ST1/EPAS1/CEBPB/TFEB/KRT19/DNAJB6/ADM/RSPO3/ZFP36L1/FZD5/MAPK1/PDGFB/GCM1	33
BP	GO:0051781	positive regulation of cell division	33/4749	87/18670	0.006727	0.06044	0.04917	AURKB/IL1B/KIF14/VEGFA/KIF23/CIT/PDGFA/KIF20B/RACGAP1/CDC6/SVIL/TGFB3/FGF9/PKP4/OSM/PRKCE/ECT2/SIRT2/CDC14B/YBX1/CENPV/FGF8/LBH/PPBP/THBS4/TGFB1/CDC42/CDC25B/CXCR5/PDGFB/NUP62/VEGFC/TAS2R13	33
BP	GO:1904950	negative regulation of establishment of protein localization	66/4749	197/18670	0.006745	0.06052	0.04924	NDFIP2/IL1B/NLRP3/IL10/TLR8/PIM3/RAB11FIP1/CDK5/DNAJA1/PML/TNF/TNFRSF4/CD200/BTN2A2/TNFRSF21/FOXP3/ADTRP/BAG4/IL1R2/RSAD2/FRMD4A/SYT4/PTGER4/ENY2/ENHO/TERF1/UBE2G2/EZR/ANXA5/INSIG1/PSMD9/IL27RA/C1QTNF3/TLR6/CHP1/PARK7/RAB11FIP3/ACVR1C/ANXA4/CABP1/DEFB114/SYT11/SNX12/SRGN/ZC3H12A/BAG3/RABGEF1/LILRA5/SFRP1/RAB23/GHRL/ADIPOQ/CD34/RAB11FIP5/F2R/GOPC/HDAC9/CARD8/PFKL/NPFF/NDUFAF2/UBAC2/GDI1/USP17L2/LRRC32/BARD1	66
BP	GO:0009116	nucleoside metabolic process	44/4749	123/18670	0.006899	0.06181	0.05029	ACPP/TYMP/APOBEC3H/GAMT/DHODH/TK1/TJP2/APOBEC3B/ERH/DTYMK/HPRT1/AK3/PNP/NME4/UPRT/MRI1/PRPSAP2/AICDA/NME3/ENPP4/MTRR/MTAP/AK4/DPYD/MOCS1/APRT/IMPDH1/ENTPD4/LRGUK/RAB23/CARD11/GNMT/GUK1/AMPD3/ENOPH1/NT5E/CMPK1/CTPS2/UCK2/PRPS1/NFS1/NME9/NT5C2/NME2	44
BP	GO:0048144	fibroblast proliferation	32/4749	84/18670	0.007005	0.06268	0.05099	CDKN1A/PPARG/PDGFA/CCNA2/ANXA2P2/CDC6/PML/SIRT6/E2F1/SKI/BAX/ANXA2/CCNB1/CD74/S100A6/TP53INP1/LTA/FOSL2/EMD/JUN/PEX2/FTH1/NLRC3/IL13/SFRP1/ESR1/NUPR1/TGFB1/BMI1/PDGFB/B4GALT7/FBXO4	32
BP	GO:0010001	glial cell differentiation	72/4749	218/18670	0.007072	0.06318	0.0514	EGR2/LIF/IL1B/NOTCH1/TP73/CDK1/PPARG/DUSP10/ADORA2A/NTRK2/TTBK1/GRN/CNTF/GPC1/CDK5/CD9/ASCL1/TNF/GSN/SKI/TLR4/CDKN2C/TNFRSF21/MTOR/LDLR/CNP/STAT3/PRDM8/NKX2-1/FA2H/NAB2/CLU/NTRK3/EIF2B3/SPINT1/PICK1/MPP5/NDRG1/TLR2/VTN/SLC45A3/DRD1/LRP1/SOX8/FPR2/NAB1/ERCC2/ERBB2/ADAM22/WDR1/MMP24/DTX1/SOX11/VIM/PRPF19/POU3F1/B4GALT5/SIRT2/IFNGR1/S100A8/TNFRSF1B/C1QA/DICER1/MBD1/MED12/DLL1/NKX6-2/TGFB1/MAPK1/HDAC10/ILK/GCM1	72
BP	GO:0045453	bone resorption	25/4749	62/18670	0.007122	0.06342	0.0516	NCDN/CSF1R/ACP5/RAC1/TFRC/SPP1/LRRK1/TPP1/SRC/PPARGC1B/RAB3D/S1PR1/PRKCA/PLEKHM1/CA2/RAC2/IL7/BGLAP/TNFRSF11B/TRAF6/TMEM119/TNFSF11/ZNF675/TMEM64/P2RX7	25
BP	GO:0048857	neural nucleus development	25/4749	62/18670	0.007122	0.06342	0.0516	TTBK1/YWHAH/YWHAE/ASCL1/SYNGR3/HSPA5/CNP/NKX2-1/SEC16A/MAPKAP1/FGF9/SCRIB/NDRG2/YWHAQ/BASP1/CKB/HOXB2/GNB4/INA/GLUD1/PADI2/SIRT2/ZNF148/CDC42/ACTB	25
BP	GO:0006754	ATP biosynthetic process	55/4749	160/18670	0.007128	0.06342	0.0516	TPI1/SEC13/GAPDH/HK1/TREX1/LDHA/PFKFB3/ENO1/PGAM1/PFKP/GPI/CBFA2T3/SIRT6/HK2/NUP98/ENTPD5/DNAJC30/STAT3/PGM2L1/PKM/ALDOC/VCP/OGDH/HTR2A/PFKFB4/NUP153/PINK1/DDIT4/VPS9D1/GALK1/PFKFB2/NUP88/ENO3/PRKAG2/POM121C/AK4/NUP205/RAE1/NUP50/ALDOA/IL4/INSR/NUPR1/SPHK2/NUP93/PFKL/ALDOB/NUP35/AAAS/TAZ/TGFB1/NUP62/P2RX7/SEH1L/NCOR1	55
BP	GO:0043488	regulation of mRNA stability	60/4749	177/18670	0.007178	0.06374	0.05186	TIRAP/YWHAZ/SERBP1/ZFP36/E2F1/HSPA1A/ZC3H12D/PLEKHN1/MTOR/PSMD8/HNRNPA0/UBB/PSMD1/PSMD2/PSMF1/CIRBP/UPF1/RPS27A/ZFP36L2/PRKCA/ALKBH5/RBM46/UBA52/MEX3D/PSMD9/PSMA5/RBM23/FMR1/PSMB7/EXOSC2/PSMD5/ZC3H12A/VIM/PSME2/ELAVL1/CSDC2/YTHDF3/FASTKD3/METTL16/TNFSF13/SAMD4B/GIGYF2/PSMB5/RBM38/MAPKAPK2/YBX1/ZFP36L1/PSMB4/PSMA3/TBRG4/AXIN2/PSMD10/PSMB1/PSMD7/PSMB3/PSMC5/TNPO1/KHSRP/EXOSC9/PSMD11	60
BP	GO:0035690	cellular response to drug	115/4749	369/18670	0.007184	0.06374	0.05186	EGR1/PPIF/IL1B/CDK1/NR4A3/ICAM1/GNA15/CASP9/KLF2/IL10/NTRK1/KLF4/BCL11A/CCNA2/SPI1/TREX1/SIRPA/TFRC/PPP1R14A/PDE4A/RBM22/EIF4EBP1/HSPA5/TNF/CYBB/MAP1LC3A/MT2A/RAD51/PLEKHA1/MSX1/NR3C1/RIPK3/FXN/SRC/HMOX1/ARHGEF2/CFLAR/NDOR1/P2RY11/EFTUD2/CDK2/AMIGO1/PDXP/PDE4B/AXL/ADCY6/ATF4/LY6H/RPS3/DCPS/NQO1/FOXO1/KCNMB1/CBX8/MAP3K5/PINK1/TRPM4/DDIT4/AIF1/KLF9/EZH2/TIMELESS/RECQL5/NOD2/DRD1/ATP2B4/TP53INP1/ARG1/GNAI2/PARK7/STK25/PPP5C/FMR1/CRK/PRKCE/ECT2/ACER2/ADCY3/CYBA/ZC3H12A/ADAM15/VIM/CTNNA1/DDX11/SFRP1/TRAF2/GABPA/ADIPOQ/KCNH2/MAP4K1/PRNP/RIPK2/GCLC/CHRNA3/CHEK2/P2RY1/GNAQ/MTR/SPHK2/CCL7/PPP1R9B/PLCB1/ID1/ATG7/TGFB1/NET1/PPP1R12A/MAPK1/PDGFB/PTAFR/P2RX7/BAD/FYN/ACTB/SIRT1	115
BP	GO:0008360	regulation of cell shape	52/4749	150/18670	0.007241	0.06416	0.0522	CDC42EP4/VEGFA/ICAM1/CSF1R/FES/HCK/PLXNB2/CYFIP1/PLXNB1/MYH10/ARHGEF18/FGD2/CDC42SE1/S100A13/CDC42EP1/RHOG/LIMD1/CCL3/PLXNA1/FMNL1/ARHGAP35/CCL2/PHIP/EZR/CORO1A/WDPCP/PLXND1/PARVB/ARAP1/ARHGAP15/CRK/ATP10A/WDR1/RHOF/RHOV/SYNE3/SHROOM3/RHOU/ALDOA/MYH9/EPB41/P2RY1/CDC42SE2/FAM171A1/SEMA4D/HEXB/TPM1/ARHGAP18/CCL7/C15orf62/CDC42/FYN	52
BP	GO:2001021	negative regulation of response to DNA damage stimulus	31/4749	81/18670	0.007289	0.06441	0.0524	TWIST1/DYRK3/ZNF385A/PARPBP/RMI2/SNAI1/FBXO5/TP53BP1/CLU/CD74/POLQ/MAGEF1/RPS3/BID/TFIP11/TAF9B/MUC1/RECQL5/BCL2L12/CD44/BCL2L1/XRCC1/AUNIP/MAD2L2/HELB/CHEK2/OGG1/PSMD10/ERCC1/TERF2/SIRT1	31
BP	GO:0033619	membrane protein proteolysis	24/4749	59/18670	0.007289	0.06441	0.0524	IL1B/FURIN/IL10/CTSH/TIMP4/TIMP2/ADAM19/SNX9/TNF/TMPRSS6/SPPL3/PARL/NAPSA/TIMP1/SNX33/ERAP1/MYH9/TNFRSF1B/TIMP3/MBTPS2/TRAF6/TGFB1/ADAM9/P2RX7	24
BP	GO:0032689	negative regulation of interferon-gamma production	16/4749	35/18670	0.007336	0.06455	0.05251	IL10/TNFSF4/LGALS9/HMGB1/TLR4/FOXP3/HAVCR2/AXL/PGLYRP3/PDCD1LG2/ZC3H12A/PRNP/C1QBP/RARA/CD96/GATA3	16
BP	GO:0046466	membrane lipid catabolic process	16/4749	35/18670	0.007336	0.06455	0.05251	NAGA/NEU4/PDXDC1/GM2A/NEU1/PPT1/GBA/ACER1/ACER2/ASAH2/ASAH2B/NEU3/MGST2/GALC/HEXB/FUCA1	16
BP	GO:1904031	positive regulation of cyclin-dependent protein kinase activity	16/4749	35/18670	0.007336	0.06455	0.05251	CDKN1A/TTBK1/CDC6/PSRC1/CKS2/CCNB1/SRC/CKS1B/PKD2/CCNT2/CCNK/MNAT1/CCNY/PSMD10/CCND1/PDGFB	16
BP	GO:0036499	PERK-mediated unfolded protein response	11/4749	21/18670	0.007356	0.06464	0.05259	ATF3/HSPA5/PTPN1/HERPUD1/ATF4/ASNS/CCL2/DDIT3/EIF2AK3/PPP1R15A/TMEM33	11
BP	GO:0009435	NAD biosynthetic process	23/4749	56/18670	0.007437	0.06527	0.0531	TPI1/GAPDH/HK1/PTGIS/ENO1/PGAM1/PFKP/GPI/HK2/PGM2L1/PKM/ALDOC/NAMPT/PARP16/ENO3/IDO1/ALDOA/RNLS/PFKL/ALDOB/NMNAT1/NMNAT3/ASPDH	23
BP	GO:0007599	hemostasis	107/4749	341/18670	0.007448	0.06527	0.0531	TYRO3/ITGA2/GNA15/ADORA2A/SH2B2/MICAL1/TSPAN32/SRF/PDGFA/RCOR1/RAC1/PTPN6/PLAUR/ENTPD1/ZNF385A/DGKD/HPSE/ANXA2P2/CEACAM1/CD9/YWHAZ/CAPZB/GPI/ADRA2B/PROS1/TMPRSS6/TLR4/PROC/PLAU/SERPINE1/ADTRP/ANXA2/F5/CLIC1/ACTG1/VKORC1/DOCK8/PLAT/SRC/CBX5/DGKZ/MERTK/P2RX1/ABAT/F2RL2/ARRB1/GNAS/DOCK1/AXL/FZD6/P2RX6/CD177/ENTPD2/BLOC1S4/PIK3R5/AK3/HPS4/VAV2/PRKCA/ANXA5/ADAMTS13/A2M/VTN/PRCP/FERMT3/DTNBP1/RAB27A/CAPZA1/ENPP4/PRKCE/KLKB1/SCUBE1/FIBP/HBG1/TBXA2R/SERPING1/F3/CD34/MYH9/P2RX5/F2R/HBB/DOCK9/ITGA2B/PRKCB/PRKACB/P2RY1/C1QBP/GNAQ/TRPC7/PAPSS2/HMG20B/PROZ/SERPINA10/EHD3/CDC42/WAS/AKAP10/MAPK1/PDGFB/ZFPM1/GATA3/P2RX7/TFPI/FYN/ILK/ACTB	107
BP	GO:0002707	negative regulation of lymphocyte mediated immunity	17/4749	38/18670	0.007539	0.06598	0.05368	PTPN6/BCL6/CEACAM1/LGALS9/FOXP3/SMAD7/HLA-G/HAVCR2/CLEC4G/PTPRC/HLA-E/DUSP22/MICA/ARG1/CRK/IL7R/CD96	17
BP	GO:0031638	zymogen activation	22/4749	53/18670	0.00756	0.06598	0.05368	FURIN/CTSH/PERP/ENO1/ANXA2P2/PLAU/SERPINE1/ANXA2/ASPH/PLAT/CYFIP2/GGT1/BAK1/KLK1/CTSZ/KLKB1/IFI16/CIDEB/RIPK2/C1R/BAD/KLK3	22
BP	GO:0038066	p38MAPK cascade	22/4749	53/18670	0.00756	0.06598	0.05368	IL1B/VEGFA/DUSP10/GADD45G/LGALS9/ZFP36/GADD45A/MAP2K3/MAP3K5/EZR/CYLD/PHLPP1/MAP3K3/ZC3H12A/MINK1/EMC10/MAPKAPK2/ZFP36L1/MIR181D/NCF1/PJA2/DUSP1	22
BP	GO:0046488	phosphatidylinositol metabolic process	59/4749	174/18670	0.007574	0.06601	0.0537	TTC7A/MBOAT7/PTPN13/CSF1R/PDGFA/SBF1/MTMR3/SOCS2/PLBD1/TTC7B/PLEKHA1/SOCS3/INPP4A/PLA2G12A/HTR2A/PIGK/SH3YL1/PIGH/TMEM150A/PIK3R5/PITPNM1/PIKFYVE/DPM2/MTMR9/IMPA2/PLEKHA2/PIP5K1B/PIGQ/PI4K2A/PIGO/SLA2/FPR2/PLEKHA8/AGAP2/INPP1/PIGC/MTMR14/FAM126B/PIGW/PIK3C3/IP6K1/PLA2G2A/LCLAT1/PIP4K2A/PIK3R4/PIGM/PIGA/IP6K2/PIP4K2B/PLA2G5/ATM/PIP5K1A/PLCB1/GALR2/PLEKHA3/PDGFB/IP6K3/PIGG/PIGT	59
BP	GO:1901222	regulation of NIK/NF-kappaB signaling	42/4749	117/18670	0.007627	0.06636	0.05399	IL1B/IL18/NLRP3/NR3C2/RASSF2/BCL3/TIRAP/LGALS9/HMGB1/TNF/TLR4/NOL3/PDCD4/TRIP6/HAVCR2/LIMS1/RPS3/TNFRSF10B/CYLD/ACTN4/TLR2/TRIM44/LITAF/NOD2/TRAF4/IRAK1/ADIPOR1/IL18R1/C1QTNF3/TLR6/FBXW11/NFKBIA/NLRC3/ZC3H12A/TRAF2/TRAF6/TSPAN6/EDAR/PRDX1/PTP4A3/ILK/IL23A	42
BP	GO:1901657	glycosyl compound metabolic process	51/4749	147/18670	0.007635	0.06636	0.05399	ACPP/NAGA/TYMP/APOBEC3H/GAMT/DHODH/TK1/TJP2/APOBEC3B/ERH/TRMT12/DTYMK/HPRT1/AK3/PNP/NME4/UPRT/MRI1/FUCA2/PRPSAP2/GBA/AICDA/NME3/ENPP4/MTRR/MTAP/AK4/DPYD/MOCS1/APRT/IMPDH1/ENTPD4/LRGUK/RAB23/CARD11/GNMT/GUK1/AMPD3/ENOPH1/NT5E/CMPK1/CTPS2/UCK2/GUSB/PRPS1/NFS1/NME9/FUCA1/NT5C2/AKR1A1/NME2	51
BP	GO:0042398	cellular modified amino acid biosynthetic process	21/4749	50/18670	0.007652	0.0664	0.05402	MTHFD1L/CHAC1/GAMT/CHAC2/CARNS1/GGT1/MTHFS/DHFR/OPLAH/TMLHE/MTHFD1/PARK7/CKB/MGST2/GCLC/GGT7/ALDH7A1/ALDH9A1/PLOD3/PTDSS1/GSS	21
BP	GO:0050798	activated T cell proliferation	18/4749	41/18670	0.00766	0.0664	0.05402	IL18/LGALS9/HMGB1/IL2RA/BTN2A2/FOXP3/RIPK3/RPS3/SATB1/IL12RB1/ARG1/TNFSF9/PDCD1LG2/PRNP/HHLA2/LRRC32/FYN/IL23A	18
BP	GO:0034605	cellular response to heat	48/4749	137/18670	0.007701	0.06644	0.05405	CDKN1A/HSPA2/SEC13/YWHAE/HSPA5/HSPA1A/NUP98/CXCL10/MTOR/BAG4/HMOX1/HSPA9/VCP/CAMK2A/MYOF/NUP153/HSF2/ST8SIA1/CHORDC1/HSF4/NUP88/STAC/IRAK1/SUMO1/CAMK2G/POM121C/NUP205/RAE1/NUP50/BAG3/HSPA6/BAG2/DNAJB6/CAMK2D/CD34/MAPKAPK2/HSPA1L/ATR/HSPA14/NUP93/NUP35/ATM/AAAS/MAPK1/NUP62/SEH1L/MLST8/SIRT1	48
BP	GO:0035722	interleukin-12-mediated signaling pathway	20/4749	47/18670	0.007706	0.06644	0.05405	LMNB1/IL10/ANXA2/PITPNA/PDCD4/HSPA9/IL12RB2/GSTO1/CFL1/IL12RB1/RALA/CAPZA1/STAT4/MTAP/PSME2/CNN2/PLCB1/CDC42/PAK2/JAK1	20
BP	GO:0045058	T cell selection	20/4749	47/18670	0.007706	0.06644	0.05405	JAG2/BATF/SRF/IRF4/MTOR/FOXP3/STAT3/CD74/CD1D/LY9/PTPRC/CYLD/IL12RB1/CD3E/CARD11/THEMIS/ZAP70/ZFPM1/GATA3/IL23A	20
BP	GO:0061614	pri-miRNA transcription by RNA polymerase II	20/4749	47/18670	0.007706	0.06644	0.05405	PPARG/FOSL1/IL10/SRF/KLF4/SPI1/STAT3/NR3C1/LILRB4/SMAD6/SMARCA4/ATOH8/GNL3/JUN/SMAD1/FOS/PPARD/TGFB1/PDGFB/SREBF2	20
BP	GO:0051348	negative regulation of transferase activity	91/4749	285/18670	0.007771	0.06691	0.05444	IL1B/CDKN1A/PPARG/WNK1/MVP/DUSP10/CAMK2N2/ADORA2A/DUSP4/TRIB1/CDKN2B/GSKIP/PTPN6/DUSP6/SPRED2/HEXIM1/DNAJA1/CEACAM1/CORO1C/NF2/PPP2R1A/ZFP36/PTPN1/PLK1/CDKN2C/GADD45A/SMAD7/PDCD4/SORL1/SRC/SOCS3/DTX3L/RPL5/FGFR1OP/PRDX3/FBXO5/DUSP5/SFN/PIF1/IGF1R/WWTR1/IRAK3/PTK6/TERF1/DUSP16/RPL23/PTPRC/SH3BP5L/DUSP22/DVL1/PPP2CA/CHORDC1/CDKN2A/GBA/DTNBP1/LIMK1/THY1/TAOK3/PRKAG2/CHP1/PARK7/GGNBP2/USP44/DEFB114/DEPTOR/POT1/GSK3A/DUSP18/BAG2/SFRP1/ADIPOQ/TAF7/TESC/MAD2L2/AIDA/LRP6/STK38/GNAQ/DUSP14/APC/RPL11/ZNF675/COX11/UCHL1/NUP62/PAK2/TRIB3/ILK/SIRT1/DUSP1/NPRL2	91
BP	GO:0006415	translational termination	38/4749	104/18670	0.00782	0.06706	0.05456	MRPL37/MRPL28/MRPL51/MRPS36/MRPL22/MRPL18/MRPS5/MRPS18C/MRPS11/C12orf65/UPF1/MRPS6/ABCE1/N6AMT1/MRPL20/MRPL50/MRPL36/MRPS2/MRPL35/MRPL27/MRPL15/MRPS25/TRMT112/MRPL34/MRPS14/MRPL13/PTCD3/OGFOD1/GADD45GIP1/MRPL10/MRPL54/GLE1/DAP3/GSPT1/MRPL2/MRPL39/MRPL43/MRPL48	38
BP	GO:0030593	neutrophil chemotaxis	38/4749	104/18670	0.00782	0.06706	0.05456	CXCL13/IL1B/CCL20/CCL3L3/RAC1/IL1RN/CSF3R/CCL22/TIRAP/DAPK2/LGALS3/CXCL10/PDE4D/CCL3/PDE4B/CD74/CCL2/PREX1/CCL17/ITGA1/CCL18/CXCL9/CXCL2/CXCL3/GBF1/C3AR1/RAC2/S100A8/CKLF/IL36A/C1QBP/CCL23/CCL7/PPBP/THBS4/CCL15/IL37/IL23A	38
BP	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	38/4749	104/18670	0.00782	0.06706	0.05456	IL1B/CSF2/ICAM1/FAIM2/RFFL/MCL1/LGALS3/TNF/HSPA1A/CTTN/NOL3/SERPINE1/PEA15/GPX1/LMNA/SRC/IFI6/HMOX1/ARHGEF2/CFLAR/HTT/EYA2/PHIP/FAS/TCF7L2/TNFRSF10B/STRADB/ITGA6/PARK7/BCL2L1/YAP1/IL7/SIAH2/CTNNA1/TRAF2/TNFSF10/GCLC/FYN	38
BP	GO:0150076	neuroinflammatory response	29/4749	75/18670	0.007866	0.06728	0.05473	IL1B/IL18/ADORA2A/TTBK1/TLR8/GRN/CNTF/MMP9/TNF/CD200/LDLR/CCL3/CLU/NAMPT/PTPRC/AIF1/TLR2/LRP1/TLR6/FPR2/JUN/IL13/IFNGR1/IL4/TNFRSF1B/TYROBP/C1QA/NUPR1/ATM	29
BP	GO:1902117	positive regulation of organelle assembly	29/4749	75/18670	0.007866	0.06728	0.05473	GPSM2/SDC4/FSCN1/CSF2/SPAG5/PLK4/KCTD17/TNF/CENPJ/SRC/ARHGEF5/NUMA1/SDCBP/ATMIN/HTT/ARHGAP35/SDC1/ULK1/PAN3/ZMYND10/MARK4/KIAA1324/WRAP73/LRSAM1/BMP10/PIP4K2A/RALB/PIP4K2B/NUP62	29
BP	GO:0016241	regulation of macroautophagy	58/4749	171/18670	0.007993	0.06827	0.05554	GPSM1/BNIP3L/GAPDH/ATP6V0D1/LZTS1/CDK5/MTMR3/ATP6V0B/MTOR/CAPN1/USP36/HMOX1/PIM2/ATP13A2/ATP6V1E1/HTT/FYCO1/ATP6V0C/PIKFYVE/CALCOCO2/SMURF1/PRKAB2/PINK1/QSOX1/ATP6V1A/TRIM13/ULK1/GBA/PRKAG2/SLC38A9/KIAA1324/BAG3/UVRAG/LACRT/ATP6V1G1/UBQLN2/NPRL3/IL4/ERN1/RIPK2/LRSAM1/LAMTOR4/LAMTOR2/NUPR1/PIP4K2A/ATP6V1E2/VPS13D/RALB/PIP4K2B/RRAGB/PHF23/UCHL1/SESN2/MLST8/RAB1B/RAB12/SIRT1/NPRL2	58
BP	GO:2000377	regulation of reactive oxygen species metabolic process	65/4749	195/18670	0.008075	0.06876	0.05594	IL1B/FOXM1/CDKN1A/ICAM1/KLF2/IL10/ACP5/KLF4/RAC1/PTGIS/SIRPA/CLEC7A/MPV17/TNF/HK2/NOXA1/TLR4/DDAH2/GADD45A/CTNS/MTOR/ABCD1/STAT3/TSPO/RIPK3/ABCD2/CFLAR/CLU/CD177/PKD2/FOXO1/PARL/DHFR/PINK1/CD47/ROMO1/AIF1/PRCP/ATP2B4/SIRT3/GNAI2/RAB27A/TLR6/VDAC1/FPR2/PARK7/RAC2/ZNF205/CYBA/ZC3H12A/ARF4/SIRT2/CD34/TYROBP/HBB/NNT/INSR/SPHK2/BCR/TGFB1/KLRK1/PDGFB/CX3CR1/KHSRP/FYN	65
BP	GO:0051101	regulation of DNA binding	44/4749	124/18670	0.00811	0.06876	0.05594	TWIST1/LIF/HJURP/CDCA5/CDT1/PPARG/ITGA2/DOT1L/KLF4/NEK2/IRF4/BCL3/PLAUR/MMP9/HMGB1/E2F1/SKI/ZBTB7C/MSX1/HMOX1/SRI/SUMO3/ENHO/PER2/ACD/DDIT3/TAF10/SUMO1/PARK7/JUN/ERCC2/NFKBIA/SOX11/IFI16/SIRT2/EDF1/MAD2L2/TRAF6/ZNF675/ID1/TGFB1/POU4F1/GATA3/PDX1	44
BP	GO:0030260	entry into host cell	47/4749	134/18670	0.008114	0.06876	0.05594	CD86/ANPEP/CDK1/TYRO3/ITGA2/ICAM1/SLC1A5/CD80/MRC1/HAVCR1/TFRC/LGALS9/TNFRSF4/GSN/HSPA1A/TRIM25/LDLR/TRIM26/HYAL3/FCN1/SRC/IFITM2/TRIM62/SLC52A1/HTR2A/AXL/CD74/NUP153/CCR5/CTSB/CLEC4G/LGALS1/SLC52A2/FUCA2/IFITM3/IFITM1/CD46/MID2/CR2/KPNA3/ZNF639/UVRAG/RPSA/LAMP1/CLEC5A/KRT6A/TRIM5	47
BP	GO:0044409	entry into host	47/4749	134/18670	0.008114	0.06876	0.05594	CD86/ANPEP/CDK1/TYRO3/ITGA2/ICAM1/SLC1A5/CD80/MRC1/HAVCR1/TFRC/LGALS9/TNFRSF4/GSN/HSPA1A/TRIM25/LDLR/TRIM26/HYAL3/FCN1/SRC/IFITM2/TRIM62/SLC52A1/HTR2A/AXL/CD74/NUP153/CCR5/CTSB/CLEC4G/LGALS1/SLC52A2/FUCA2/IFITM3/IFITM1/CD46/MID2/CR2/KPNA3/ZNF639/UVRAG/RPSA/LAMP1/CLEC5A/KRT6A/TRIM5	47
BP	GO:0051806	entry into cell of other organism involved in symbiotic interaction	47/4749	134/18670	0.008114	0.06876	0.05594	CD86/ANPEP/CDK1/TYRO3/ITGA2/ICAM1/SLC1A5/CD80/MRC1/HAVCR1/TFRC/LGALS9/TNFRSF4/GSN/HSPA1A/TRIM25/LDLR/TRIM26/HYAL3/FCN1/SRC/IFITM2/TRIM62/SLC52A1/HTR2A/AXL/CD74/NUP153/CCR5/CTSB/CLEC4G/LGALS1/SLC52A2/FUCA2/IFITM3/IFITM1/CD46/MID2/CR2/KPNA3/ZNF639/UVRAG/RPSA/LAMP1/CLEC5A/KRT6A/TRIM5	47
BP	GO:0051828	entry into other organism involved in symbiotic interaction	47/4749	134/18670	0.008114	0.06876	0.05594	CD86/ANPEP/CDK1/TYRO3/ITGA2/ICAM1/SLC1A5/CD80/MRC1/HAVCR1/TFRC/LGALS9/TNFRSF4/GSN/HSPA1A/TRIM25/LDLR/TRIM26/HYAL3/FCN1/SRC/IFITM2/TRIM62/SLC52A1/HTR2A/AXL/CD74/NUP153/CCR5/CTSB/CLEC4G/LGALS1/SLC52A2/FUCA2/IFITM3/IFITM1/CD46/MID2/CR2/KPNA3/ZNF639/UVRAG/RPSA/LAMP1/CLEC5A/KRT6A/TRIM5	47
BP	GO:0050663	cytokine secretion	78/4749	240/18670	0.00814	0.06886	0.05602	TWIST1/IL1B/MAPK11/NOTCH1/NLRP3/CSF1R/IL10/ISG15/TLR8/IL17A/GAPDH/HK1/LGALS9/PML/HMGB1/TNF/TNFRSF4/CD200/TLR4/BTN2A2/S100A13/LILRA2/TNFRSF21/FOXP3/MMP12/IL1R2/IL4R/FFAR2/FCN1/SRC/CCL3/PTGER4/HAVCR2/RBPJ/PNP/SPTBN1/EZR/AIF1/TLR2/ABCA1/CD58/NOD2/LRP1/IL27RA/IL26/OSM/CADM1/C1QTNF3/TLR6/IL17RC/ANXA4/DEFB114/SYT11/SRGN/IRF3/ZC3H12A/PAEP/RABGEF1/LILRA5/CARD11/IFNGR1/GHRL/BTN3A2/CD34/RIPK2/TNFRSF1B/F2R/CLEC5A/SPHK2/RAB1A/HDAC9/CARD8/FZD5/GLMN/TRIM16/GATA3/P2RX7/LRRC32	78
BP	GO:0043470	regulation of carbohydrate catabolic process	33/4749	88/18670	0.008184	0.06886	0.05602	SEC13/TREX1/PFKFB3/PGAM1/CBFA2T3/SIRT6/PPP1CB/NUP98/ENTPD5/STAT3/HTR2A/PFKFB4/NUP153/DDIT4/PFKFB2/NUP88/PRKAG2/POM121C/NUP205/RAE1/NUP50/GSK3A/PHKG2/INSR/NUPR1/NUP93/NUP35/AAAS/NUP62/P2RX7/SEH1L/NCOR1/PPP1R3B	33
BP	GO:0043506	regulation of JUN kinase activity	33/4749	88/18670	0.008184	0.06886	0.05602	DUSP10/DNAJA1/TNF/FGD2/PTPN1/PDCD4/MAP3K6/ARHGEF5/TIAM1/MAP3K2/DVL3/PAK1/RPS3/MAP3K5/NRK/MAP3K11/DTNBP1/TAOK3/TLR6/FZD8/MAP2K4/SFRP1/TRAF2/MAP4K1/ERN1/RIPK2/AIDA/TRAF6/BIRC7/TNFSF11/FZD5/ZNF675/MAP3K9	33
BP	GO:0010970	transport along microtubule	55/4749	161/18670	0.008197	0.06886	0.05602	KIF4A/KIF23/KIF1C/SFPQ/TTC30A/UXT/WDR34/BLOC1S6/DYNLRB1/BLOC1S1/UBB/ICK/CNIH2/KLC3/SUN2/HTT/FYCO1/BLOC1S4/IFT122/AP3D1/IFT172/TTC21A/DTNBP1/KIF3C/FMR1/IFT27/MAP1S/WDR60/BBS12/WDR19/BAG3/AP3M2/SNAPIN/LAMP1/IFT80/LRPPRC/ACTR1A/RHOT2/MAP1A/RAB1A/NEFL/ARL3/TMEM201/TTC26/AP3B2/COPG2/CDC42/CLUAP1/UCHL1/SPG7/SYNE2/TNPO1/SYBU/MGARP/TERF2	55
BP	GO:0099111	microtubule-based transport	55/4749	161/18670	0.008197	0.06886	0.05602	KIF4A/KIF23/KIF1C/SFPQ/TTC30A/UXT/WDR34/BLOC1S6/DYNLRB1/BLOC1S1/UBB/ICK/CNIH2/KLC3/SUN2/HTT/FYCO1/BLOC1S4/IFT122/AP3D1/IFT172/TTC21A/DTNBP1/KIF3C/FMR1/IFT27/MAP1S/WDR60/BBS12/WDR19/BAG3/AP3M2/SNAPIN/LAMP1/IFT80/LRPPRC/ACTR1A/RHOT2/MAP1A/RAB1A/NEFL/ARL3/TMEM201/TTC26/AP3B2/COPG2/CDC42/CLUAP1/UCHL1/SPG7/SYNE2/TNPO1/SYBU/MGARP/TERF2	55
BP	GO:0031532	actin cytoskeleton reorganization	37/4749	101/18670	0.008202	0.06886	0.05602	NEDD9/CSF1R/SIPA1L1/FES/HCK/CDK5/CDC42BPG/GSN/CTTN/PTPN1/PDLIM4/NTRK3/PAK1/PTK7/S1PR1/EZR/PARVB/NRK/ARAP1/RALA/DTNBP1/INSRR/MINK1/BRSK2/CD2AP/MYH9/FER/ARHGDIA/NTF3/WHAMM/PIP5K1A/TGFB1/BCAS3/CDC42/SHC1/CCL27/RAC3	37
BP	GO:1903008	organelle disassembly	37/4749	101/18670	0.008202	0.06886	0.05602	CDK1/SQSTM1/BNIP3L/DYRK3/TEX264/HK2/CTTN/MAP1LC3A/KLC1/TSPO/USP36/STX5/ATG9A/VCP/ATP13A2/PELO/HTT/AMBRA1/SMURF1/PINK1/GBA/VDAC1/PARK7/GBF1/ATG2B/GSK3A/EIF2D/WDR45/DENR/FUNDC2/VPS13D/FZD5/ZFAND1/ATG7/KIF19/SREBF2/FUNDC1	37
BP	GO:0009218	pyrimidine ribonucleotide metabolic process	12/4749	24/18670	0.008299	0.06939	0.05645	DHODH/AK5/AK3/NME4/UPRT/NME3/ENTPD4/CMPK1/CTPS2/UCK2/NME9/NME2	12
BP	GO:0042832	defense response to protozoan	12/4749	24/18670	0.008299	0.06939	0.05645	IL10/BATF/TSPAN32/IRF4/BCL3/GBP2/CLEC7A/IL4R/ARG1/CCDC88B/DEFA1B/GBP4	12
BP	GO:0000478	endonucleolytic cleavage involved in rRNA processing	7/4749	11/18670	0.008355	0.06939	0.05645	NOL9/NOP14/UTP20/BOP1/UTP23/ABT1/RCL1	7
BP	GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	7/4749	11/18670	0.008355	0.06939	0.05645	NOL9/NOP14/UTP20/BOP1/UTP23/ABT1/RCL1	7
BP	GO:0002517	T cell tolerance induction	7/4749	11/18670	0.008355	0.06939	0.05645	IL2RA/FOXP3/HLA-G/LILRB2/PHLPP1/IDO1/CD3E	7
BP	GO:0033235	positive regulation of protein sumoylation	7/4749	11/18670	0.008355	0.06939	0.05645	PIAS3/UBE2I/TOLLIP/PIAS1/GNL3/RASD2/PIAS4	7
BP	GO:0046007	negative regulation of activated T cell proliferation	7/4749	11/18670	0.008355	0.06939	0.05645	LGALS9/BTN2A2/FOXP3/ARG1/PDCD1LG2/PRNP/LRRC32	7
BP	GO:0072683	T cell extravasation	7/4749	11/18670	0.008355	0.06939	0.05645	ICAM1/RIPK3/CCR2/CCL2/IL27RA/CRK/CD99L2	7
BP	GO:0002475	antigen processing and presentation via MHC class Ib	9/4749	16/18670	0.008406	0.06939	0.05645	CD1E/CD1A/CD1C/HLA-H/HLA-G/CD1B/CD1D/HLA-E/AP3D1	9
BP	GO:0006206	pyrimidine nucleobase metabolic process	9/4749	16/18670	0.008406	0.06939	0.05645	TYMP/TYMS/DHODH/MTOR/RRM1/DPYD/CMPK1/CTPS2/MAPK1	9
BP	GO:0019377	glycolipid catabolic process	9/4749	16/18670	0.008406	0.06939	0.05645	NAGA/NEU4/GM2A/NEU1/GBA/NEU3/GALC/HEXB/FUCA1	9
BP	GO:0032695	negative regulation of interleukin-12 production	9/4749	16/18670	0.008406	0.06939	0.05645	IL10/ACP5/TLR8/TIGIT/IRAK3/PIBF1/LILRA5/C1QBP/JAK3	9
BP	GO:0061158	3'-UTR-mediated mRNA destabilization	9/4749	16/18670	0.008406	0.06939	0.05645	ZFP36/ZC3H12D/PLEKHN1/UPF1/ZFP36L2/RBM23/ZC3H12A/ZFP36L1/KHSRP	9
BP	GO:0006403	RNA localization	75/4749	230/18670	0.008539	0.07037	0.05725	MVP/SEC13/U2AF1/ZNF385A/SFPQ/ZFP36/NUP98/SMG5/POLDIP3/TST/MRPL18/IWS1/RNPS1/RPS15/HNRNPA3/ENY2/SRSF4/ZC3H3/NUP153/UPF1/CCT5/NOP10/TERF1/MAGOHB/ABCE1/ALKBH5/RFTN1/FLOT1/SUPT6H/MEX3D/NUP88/THOC3/FMR1/U2AF1L4/ZNHIT3/PARP11/POM121C/EXOSC2/NUP205/RAE1/SIDT2/NUP50/DHX38/SDAD1/UPF3A/FBL/MAGOH/WRAP53/LRPPRC/CPSF1/SMG6/ZFP36L1/GLE1/CETN2/ATR/SNUPN/CPSF6/NUP93/DDX19A/CDC40/RBM27/CETN3/NUP35/ATM/AAAS/NCBP2/A1CF/NUP62/SEH1L/KHSRP/YTHDC1/CKAP5/TERF2/NXF3/CCT3	75
BP	GO:0050772	positive regulation of axonogenesis	32/4749	85/18670	0.008546	0.07037	0.05725	SKIL/VEGFA/MAP6/NTRK2/SRF/PLXNB2/CYFIP1/PLXNB1/TNFRSF12A/SEMA7A/ZFYVE27/TIAM1/AMIGO1/NTRK3/PLXNA1/PAK1/TWF2/L1CAM/PLXND1/LRP1/LIMK1/STK25/IST1/SEMA4D/ARHGDIA/NEFL/RUFY3/SEMA5A/ADNP/TRPC5/GDI1/ILK	32
BP	GO:0031669	cellular response to nutrient levels	77/4749	237/18670	0.008586	0.07061	0.05744	VDR/CDKN1A/PPARG/GAS2L1/ICAM1/CD68/KANK2/CDKN2B/FES/SRF/BCL11A/DSC2/MTMR3/ATF3/HSPA5/CYBB/MAP1LC3A/PMAIP1/MTOR/GDAP1/ITFG2/PIM1/DAP/HMOX1/P2RY11/AMIGO1/PDXP/USF2/ATF4/NMRAL1/NUAK2/ASNS/PHEX/AMBRA1/FOXO1/CASR/FAS/PICK1/MAP3K5/WDR24/NAMPT/TRPM4/C12orf66/ULK1/GBA/JUN/SLC38A2/CYP27B1/MYBBP1A/KIAA1324/CYBA/ZC3H12A/KLF10/IFI16/KRT20/BGLAP/NPRL3/SFRP1/PIK3C3/EIF2AK3/WDR45/P2RY1/MAX/RRP8/PIK3R4/RALB/RRAGB/WRN/ATG7/MAPK1/SESN2/P2RX7/SEH1L/SREBF2/FYN/SIRT1/NPRL2	77
BP	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	36/4749	98/18670	0.0086	0.07063	0.05746	PPIF/PLAUR/ZNF385A/MCL1/ENO1/DNAJA1/MMP9/HSPA1A/RRM2B/NOL3/PTPN1/GPX1/SYVN1/SRC/SNAI1/ARHGEF2/CLU/CD74/URI1/HERPUD1/BID/PINK1/FIGNL1/BCL2A1/TAF9B/MUC1/BDKRB2/PARK7/BCL2L12/CD44/TXNDC12/BCL2L1/VNN1/NDUFA13/PDX1/SIRT1	36
BP	GO:0043467	regulation of generation of precursor metabolites and energy	54/4749	158/18670	0.008649	0.07095	0.05772	PPIF/CDK1/PHLDA2/SEC13/TREX1/PFKFB3/PGAM1/PRELID1/CBFA2T3/SIRT6/PPP1CB/NUP98/COX17/SLC25A23/ENTPD5/MTOR/ABCD1/DNAJC30/STAT3/CCNB1/VCP/HTR2A/PFKFB4/NUP153/NOA1/PRDM16/PINK1/DDIT4/PFKFB2/NUP88/PPP1R3E/PRKAG2/PARK7/EPM2AIP1/POM121C/AK4/NUP205/RAE1/NUP50/GSK3A/PHKG2/IL4/ISCU/INSR/NUPR1/SPHK2/NUP93/NUP35/AAAS/NUP62/P2RX7/SEH1L/NCOR1/PPP1R3B	54
BP	GO:0042326	negative regulation of phosphorylation	142/4749	468/18670	0.008712	0.07136	0.05806	TWIST1/LIF/PPIF/IL1B/PBK/CD109/FOXM1/PTPN13/CDKN1A/WNK1/MVP/DUSP10/CAMK2N2/ADORA2A/DUSP4/TRIB1/MICAL1/CDKN2B/GSKIP/RASSF2/KLF4/PTPN6/PMEPA1/DUSP6/SPRED2/HEXIM1/SIRPA/SNX25/DNAJA1/CEACAM1/CORO1C/ATF3/NF2/PPP2R1A/CBFA2T3/SIRT6/LRRK1/TLR4/CHRNA10/BAX/BTN2A2/UBE2B/PTPN1/PLK1/CDKN2C/GADD45A/MTOR/MYADM/STAT3/SMAD7/PARP14/PDCD4/SORL1/CCNB1/SOCS3/FGFR1OP/PRDX3/DUSP5/SFN/PDE4D/ARRB1/SAMSN1/NTRK3/IGF1R/WWTR1/IGFBP3/SMAD6/FKTN/IRAK3/FOXO1/PTK6/SYNJ2BP/DUSP16/PINK1/PTPRC/EZR/CYLD/DDIT4/SH3BP5L/DUSP22/DVL1/PPP2CA/CHORDC1/PRDM15/BAK1/CDKN2A/GBA/DTNBP1/NDRG2/THY1/SIRT3/BDKRB2/TAOK3/PRKAG2/CHP1/LDLRAD4/RAPGEF1/PARK7/JUN/PPP5C/FKBP8/GGNBP2/PIBF1/DEFB114/DEPTOR/ZC3H12A/RABGEF1/C3orf33/DUSP18/SFRP1/SIRT2/ADIPOQ/TAF7/PRNP/TESC/AIDA/LRP6/NNT/TIMP3/SEMA4D/STK38/GNAQ/NUPR1/ZBED3/DUSP14/APC/PARD6A/NTF3/ZNF675/PSMD10/TGFB1/COX11/UCHL1/NUP62/P2RX7/NCOR1/PAK2/TRIB3/ILK/SIRT1/DUSP1/NPRL2	142
BP	GO:0014065	phosphatidylinositol 3-kinase signaling	51/4749	148/18670	0.008825	0.0722	0.05874	TWIST1/IL18/TYRO3/PTPN13/NTRK2/CEP55/NTRK1/KLF4/PDGFA/PTPN6/IER3/CEACAM1/STAMBP/PLXNB1/TNF/BTN2A2/ENTPD5/PLEKHA1/SRC/HTR2A/NTRK3/IGF1R/PIK3R5/FLT3/PIP5K1B/OSM/FLT1/PPP1R16B/UBE3A/ERBB2/NLRC3/FLT4/SIRT2/LTK/F2R/ZFP36L1/SEMA4D/C1QBP/INSR/PIP4K2A/NCF1/NTF3/PIP4K2B/PPARD/PIP5K1A/HCST/MAPK1/PDGFB/GATA3/FYN/SIRT1	51
BP	GO:0046631	alpha-beta T cell activation	48/4749	138/18670	0.00895	0.07313	0.05949	EBI3/CD86/IL18/RELB/NLRP3/ADORA2A/BATF/CD83/CD80/IRF4/BCL3/BCL6/CBFB/TNFSF4/LGALS9/PRDM1/HMGB1/MTOR/FOXP3/STAT3/IL4R/RSAD2/SMAD7/CCR2/PTGER4/LY9/HLX/SATB1/PNP/RORC/PTPRC/HLA-E/AP3D1/IL12RB1/IL18R1/CDH26/ZC3H12A/ITK/CD3E/RIPK2/PAX1/JAK3/RARA/ZAP70/ZFPM1/GATA3/RPL22/IL23A	48
BP	GO:1904377	positive regulation of protein localization to cell periphery	25/4749	63/18670	0.009006	0.07347	0.05977	GPSM2/SQSTM1/ITGA3/LGALS3/TNF/AKAP5/RANGRF/NUMA1/RHOG/CLIP3/PLS1/PTPN9/SPTBN1/EZR/PRKCI/STAC3/LRP1/STAC/EFCAB7/PRKCE/EPB41L2/PRNP/EPB41/ARF6/CNST	25
BP	GO:0051651	maintenance of location in cell	35/4749	95/18670	0.009014	0.07347	0.05977	GPSM2/ASPM/BCL3/HK1/CDK5/PML/HSPA5/HK2/GSN/TSPO/SORL1/KDELR2/ATP2A1/SRI/SUN2/TMSB4Y/PINK1/EZR/TWF2/INSIG1/SPAG4/FTL/PARK7/TOPORS/FTH1/SRGN/UVRAG/SYNE3/TMSB15A/ARL2BP/POLR2M/VPS13D/ARL2/SYNE2/BARD1	35
BP	GO:0007596	blood coagulation	105/4749	336/18670	0.009048	0.07365	0.05992	TYRO3/ITGA2/GNA15/ADORA2A/SH2B2/MICAL1/TSPAN32/SRF/PDGFA/RCOR1/RAC1/PTPN6/PLAUR/ENTPD1/DGKD/HPSE/ANXA2P2/CEACAM1/CD9/YWHAZ/CAPZB/ADRA2B/PROS1/TMPRSS6/TLR4/PROC/PLAU/SERPINE1/ADTRP/ANXA2/F5/CLIC1/ACTG1/VKORC1/DOCK8/PLAT/SRC/CBX5/DGKZ/MERTK/P2RX1/ABAT/F2RL2/ARRB1/GNAS/DOCK1/AXL/FZD6/P2RX6/CD177/ENTPD2/BLOC1S4/PIK3R5/AK3/HPS4/VAV2/PRKCA/ANXA5/ADAMTS13/A2M/VTN/PRCP/FERMT3/DTNBP1/RAB27A/CAPZA1/ENPP4/PRKCE/KLKB1/SCUBE1/FIBP/HBG1/TBXA2R/SERPING1/F3/CD34/MYH9/P2RX5/F2R/HBB/DOCK9/ITGA2B/PRKCB/PRKACB/P2RY1/C1QBP/GNAQ/TRPC7/PAPSS2/HMG20B/PROZ/SERPINA10/EHD3/CDC42/WAS/AKAP10/MAPK1/PDGFB/ZFPM1/GATA3/P2RX7/TFPI/FYN/ILK/ACTB	105
BP	GO:0051236	establishment of RNA localization	65/4749	196/18670	0.009138	0.07428	0.06043	MVP/SEC13/U2AF1/SFPQ/ZFP36/NUP98/SMG5/POLDIP3/TST/MRPL18/IWS1/RNPS1/RPS15/HNRNPA3/ENY2/SRSF4/ZC3H3/NUP153/UPF1/TERF1/MAGOHB/ABCE1/ALKBH5/RFTN1/FLOT1/SUPT6H/NUP88/THOC3/FMR1/U2AF1L4/PARP11/POM121C/NUP205/RAE1/SIDT2/NUP50/DHX38/SDAD1/UPF3A/MAGOH/LRPPRC/CPSF1/SMG6/ZFP36L1/GLE1/CETN2/ATR/SNUPN/CPSF6/NUP93/DDX19A/CDC40/RBM27/CETN3/NUP35/ATM/AAAS/NCBP2/NUP62/SEH1L/KHSRP/YTHDC1/CKAP5/TERF2/NXF3	65
BP	GO:0042267	natural killer cell mediated cytotoxicity	24/4749	60/18670	0.009272	0.07528	0.06124	IL18/IL21/PTPN6/CEACAM1/LGALS9/ULBP2/RAET1E/TUBB/HLA-G/SH2D1A/HAVCR2/TUBB4B/CORO1A/HLA-E/MICA/LAG3/CADM1/RAB27A/UNC13D/CRK/LAMP1/ULBP1/KLRK1/PRDX1	24
BP	GO:0018205	peptidyl-lysine modification	122/4749	397/18670	0.00935	0.07579	0.06166	EGR1/TWIST1/EGR2/LIF/IL1B/GTF3C4/DOT1L/BCL11A/IRF4/SPI1/PHF19/SENP7/DPF3/SETD7/NUP98/BRCA2/PHF10/PIAS3/FOXP3/SMARCB1/LMNA/CRTC2/ING3/NAP1L2/ING5/KANSL3/SAE1/TGM2/IWS1/SUMO4/ARRB1/MORF4L2/KANSL1L/UBE2I/BLOC1S1/VPS33B/SETD6/SUMO3/KAT2A/NUP153/PRDM16/ACTL6A/CTH/BCOR/TOLLIP/TAF1L/ZNF304/PIAS1/TRPM4/YEATS4/SUPT3H/EED/BRD4/EZH2/SETD4/SUPT6H/DOHH/TAF9B/MUC1/NUP88/GNL3/TAF6L/SIRT3/TAF10/SUMO1/PARK7/RASD2/TOPORS/CHEK1/MCRS1/POM121C/KIAA1586/NUP205/RAE1/HMG20A/PIAS2/NUP50/SETD1B/LOXL1/MLLT6/SIRT2/PIAS4/BRPF3/TAF7/SETDB2/KAT6B/WDR5B/POR/DPF1/DMRTC2/SUMO1P1/TADA2A/DHPS/SPHK2/WDR82/NUP93/CTBP1/HDAC9/PLOD3/ARID4A/CAMKMT/HMG20B/SENP6/NUP35/AAAS/KDM4C/TGFB1/RNF212/ZNF451/HDAC10/SETDB1/NUP62/TRIM16/LDB1/GATA3/CPA4/SEH1L/TADA1/HINT2/KAT6A/MAGEA2B/SIRT1	122
BP	GO:0007163	establishment or maintenance of cell polarity	69/4749	210/18670	0.009358	0.07579	0.06166	SAPCD2/KIF2C/CENPA/GPSM2/FSCN1/KIF20B/FRMD4B/EPHB1/GSN/ANK1/PLK1/LMNA/DOCK8/FRMD4A/NUMA1/RHOG/NDC80/ARHGEF2/MAPKAP1/PAK1/PTK7/AMOT/HTT/MPP7/ARHGAP35/SYNJ2BP/FAM89B/FGF13/MPP5/CLASP2/WDPCP/PRKCI/CFL1/PARVB/SCRIB/ARPC5/WNT7A/STK25/GBF1/CRK/WDR1/PARD6G/RHOF/CTNNA1/BRSK2/RHOV/CLIC4/ARF4/RHOU/DLG5/KRIT1/MYH9/ACTR1A/NSFL1C/CYTH1/PARD6B/ARF6/PARD6A/MCPH1/LIN7C/RUFY3/BCAS3/CDC42/KIF26B/CDH5/PDZD11/GATA3/CKAP5/ILK	69
BP	GO:0006672	ceramide metabolic process	34/4749	92/18670	0.009445	0.07639	0.06215	SGMS1/NAGA/NEU4/SPTSSA/SGMS2/PPP2R1A/TNF/GM2A/NEU1/ITGB8/FA2H/P2RX1/PPP2CA/GBA/ACER1/ELOVL1/ACER2/PLA2G15/ASAH2/B4GALT5/ASAH2B/ORMDL2/NEU3/FUT6/GALC/SPHK2/HEXB/AGK/ST8SIA3/ALDH5A1/CERS3/ST6GALNAC6/P2RX7/ORMDL3	34
BP	GO:0019320	hexose catabolic process	23/4749	57/18670	0.009521	0.07682	0.06249	TPI1/GAPDH/HK1/GLB1/ENO1/PGAM1/PFKP/GPI/HK2/PGM2L1/PKM/ALDOC/GALK2/GALK1/PFKFB2/ENO3/GALM/ALDOA/FUT6/GALT/PFKL/ALDOB/BAD	23
BP	GO:0043525	positive regulation of neuron apoptotic process	23/4749	57/18670	0.009521	0.07682	0.06249	CASP9/GRN/MYBL2/MCL1/CDK5/ASCL1/TNF/BAX/CCL3/ATF4/NQO1/PAK3/ITGA1/MAP3K11/DDIT3/JUN/TFAP2B/CTSZ/MAP2K4/PRNP/TYROBP/NUPR1/ATM	23
BP	GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	14/4749	30/18670	0.009546	0.07683	0.0625	CD86/IL18/NLRP3/CD83/CD80/TNFSF4/LGALS9/FOXP3/IL4R/HLX/IL12RB1/RIPK2/RARA/IL23A	14
BP	GO:0050869	negative regulation of B cell activation	14/4749	30/18670	0.009546	0.07683	0.0625	HMGB3/IL10/BCL6/TNFRSF21/FOXP3/CTLA4/SAMSN1/BTK/SLA2/TNFRSF13B/MNDA/SFRP1/TYROBP/ATM	14
BP	GO:0051224	negative regulation of protein transport	64/4749	193/18670	0.009646	0.07753	0.06307	NDFIP2/IL1B/NLRP3/IL10/TLR8/PIM3/RAB11FIP1/CDK5/PML/TNF/TNFRSF4/CD200/BTN2A2/TNFRSF21/FOXP3/ADTRP/BAG4/IL1R2/RSAD2/FRMD4A/SYT4/PTGER4/ENY2/ENHO/UBE2G2/EZR/ANXA5/INSIG1/PSMD9/IL27RA/C1QTNF3/TLR6/CHP1/PARK7/RAB11FIP3/ACVR1C/ANXA4/CABP1/DEFB114/SYT11/SNX12/SRGN/ZC3H12A/BAG3/RABGEF1/LILRA5/SFRP1/RAB23/GHRL/ADIPOQ/CD34/RAB11FIP5/F2R/GOPC/HDAC9/CARD8/PFKL/NPFF/NDUFAF2/UBAC2/GDI1/USP17L2/LRRC32/BARD1	64
BP	GO:0019674	NAD metabolic process	29/4749	76/18670	0.009687	0.07776	0.06326	TPI1/GAPDH/HK1/LDHA/PTGIS/ENO1/PGAM1/PFKP/GPI/HK2/PGM2L1/PKM/ALDOC/VCP/MDH2/NAMPT/NADK/PARP16/ENO3/NUDT17/IDO1/ALDOA/NT5E/RNLS/PFKL/ALDOB/NMNAT1/NMNAT3/ASPDH	29
BP	GO:0060249	anatomical structure homeostasis	133/4749	437/18670	0.009744	0.07812	0.06356	NCDN/AURKB/VEGFA/NOTCH1/TYRO3/CSF1R/ACP5/SRF/EXO1/NEK2/RAC1/CTSH/TP53INP2/TFRC/CDK5/BBS2/SPP1/PML/CHMP2B/CSF1/SIRT6/LRRK1/BRCA2/CDH23/TLR4/AKT3/NCS1/BAX/TPP1/CCDC66/SMG5/FEN1/HOMER2/RAD51/ACTG1/CCR2/SRC/PPARGC1B/P2RX1/HOMER1/SPATA7/GNAS/PIF1/LYZ/WWTR1/RAB3D/XRCC6/CCNE2/UPF1/S1PR1/RFC2/CCT5/NOP10/MDM1/TERF1/PRKCA/CORO1A/PIGR/TFIP11/USH1G/POLD4/TNKS2/MKKS/ACD/NOD2/CTC1/GNL3/RCN3/NAPSA/PLEKHM1/CNR1/POLE/CHRNA1/CUBN/ZG16B/CA2/BBS12/RAC2/EPAS1/RECQL4/YAP1/BAG3/IL7/TFF1/LACRT/POT1/XRCC3/ZNF830/XRCC1/CALB2/LCN1/WRAP53/BGLAP/YLPM1/ALDOA/DNA2/GIGYF2/TNFRSF11B/CD34/F2R/FGGY/SMG6/ATR/P2RY1/MAP1A/TRAF6/CACNB2/LIPA/TMEM119/TNFSF11/TINF2/ATM/ZNF675/WRN/SMC5/TGFB1/TMEM64/DNAJB2/MAPK1/LDB1/P2RX7/ANKRD11/PRDX1/ERCC1/FBXO4/BARD1/RAC3/ZBTB48/PIWIL4/POLE2/TERF2/CCT3/ACTB	133
BP	GO:0001914	regulation of T cell mediated cytotoxicity	15/4749	33/18670	0.009909	0.07905	0.06431	CD1E/CEACAM1/CD1A/CD1C/RIPK3/HLA-H/HLA-G/CD1B/CD1D/PTPRC/HLA-E/IL12RB1/IL7R/P2RX7/IL23A	15
BP	GO:0036314	response to sterol	15/4749	33/18670	0.009909	0.07905	0.06431	PTCH1/LRP8/GRAMD1C/PMVK/CCL3/CCR5/RORC/GRAMD1B/ABCA1/INSIG1/LRP6/OSBPL7/GRAMD1A/CYP7A1/TGFB1	15
BP	GO:0050718	positive regulation of interleukin-1 beta secretion	15/4749	33/18670	0.009909	0.07905	0.06431	NLRP3/TLR8/HK1/LGALS9/HMGB1/TLR4/LILRA2/CCL3/NOD2/LILRA5/RIPK2/CARD8/FZD5/TRIM16/P2RX7	15
BP	GO:0060603	mammary gland duct morphogenesis	15/4749	33/18670	0.009909	0.07905	0.06431	VDR/CSF1R/PTCH1/PML/CSF1/SRC/ETV5/KDM5B/SCRIB/LRP5L/DDR1/BTRC/ESR1/LRP6/TGFB1	15
BP	GO:0042476	odontogenesis	46/4749	132/18670	0.009951	0.07929	0.06451	TWIST1/JAG2/PERP/CSF3R/TP63/NF2/CSF1/BAX/SERPINE1/MSX1/MYO5A/SRC/PAM/TGFB3/PHEX/FAM20C/BCOR/RUNX2/FOXO1/SDC1/LRP4/CNNM4/ITGA6/AMTN/ROGDI/ACVR2B/CA2/BSG/CTNNA1/BGLAP/ADM/TNFRSF11B/CD34/LRP6/KLK5/TRAF6/FGF8/AXIN2/TNFSF11/EDAR/HTRA1/TGFB1/CEMP1/LAMA5/AMELX/ANKRD11	46
BP	GO:0006282	regulation of DNA repair	43/4749	122/18670	0.01	0.0794	0.0646	TWIST1/FOXM1/PML/HMGB1/SIRT6/RAD51/RAD51AP1/NUDT16/PARPBP/RMI2/DTX3L/TP53BP1/POLQ/MAGEF1/UBE2N/RPS3/EYA2/CBX8/TFIP11/ERCC8/FIGNL1/TIMELESS/RECQL5/RNF8/BRCC3/CHEK1/XRCC1/WRAP53/AUNIP/DDX11/MAD2L2/HELB/RAD52/FAM168A/AXIN2/OGG1/CUL4A/WAS/MGMT/HDAC10/RNF168/TERF2/SIRT1	43
BP	GO:0019079	viral genome replication	43/4749	122/18670	0.01	0.0794	0.0646	NOTCH1/TOP2A/IFIT1/CXCR6/ISG15/APOBEC3H/MX1/TNF/SMARCB1/IFIT5/RSAD2/IFITM2/PPIH/VCP/BST2/MORC2/OASL/CCL2/ISG20/TBC1D20/BANF1/IFITM3/AICDA/IFITM1/FMR1/NFIA/CCNK/RAD23A/ZC3H12A/OAS1/CNOT7/IFI16/ILF3/EEA1/ZC3HAV1/HTATSF1/STAU1/CTBP1/STOM/NUCKS1/CDC42/SETDB1/UBP1	43
BP	GO:1905477	positive regulation of protein localization to membrane	43/4749	122/18670	0.01	0.0794	0.0646	TP73/SQSTM1/ITGA3/YWHAH/CDK5/LGALS3/YWHAE/TP63/YWHAZ/TNF/E2F1/AKAP5/PMAIP1/RANGRF/RHOG/SFN/CLIP3/PLS1/PAK1/PTPN9/PDCD5/NMT1/LRP4/BID/SPTBN1/EZR/PRKCI/STAC3/TFDP2/LRP1/STAC/YWHAQ/CHP1/EFCAB7/ERBB2/PRKCE/PRNP/ARF6/STOM/TGFB1/CNST/BAD/FYN	43
BP	GO:0046128	purine ribonucleoside metabolic process	28/4749	73/18670	0.01008	0.07947	0.06465	ACPP/GAMT/TJP2/HPRT1/AK3/PNP/NME4/MRI1/NME3/ENPP4/MTRR/MTAP/AK4/MOCS1/APRT/IMPDH1/LRGUK/RAB23/CARD11/GNMT/GUK1/AMPD3/ENOPH1/NT5E/NFS1/NME9/NT5C2/NME2	28
BP	GO:0000028	ribosomal small subunit assembly	10/4749	19/18670	0.01009	0.07947	0.06465	RPS27/RPL38/RPS10/RPS5/RPS15/MRPS11/RPS19/RPSA/ABT1/RPS28	10
BP	GO:0006555	methionine metabolic process	10/4749	19/18670	0.01009	0.07947	0.06465	SMS/MRI1/MTHFD1/BHMT/MTRR/MTAP/GNMT/ENOPH1/MTR/BHMT2	10
BP	GO:0045063	T-helper 1 cell differentiation	10/4749	19/18670	0.01009	0.07947	0.06465	RELB/CD80/TNFSF4/HMGB1/MTOR/IL4R/HLX/IL18R1/RIPK2/JAK3	10
BP	GO:0051546	keratinocyte migration	10/4749	19/18670	0.01009	0.07947	0.06465	HBEGF/MMP9/MTOR/MAPRE2/IQSEC1/ARF6/PPARD/LTB4R2/HAS2/ADAM9	10
BP	GO:0090201	negative regulation of release of cytochrome c from mitochondria	10/4749	19/18670	0.01009	0.07947	0.06465	PPIF/PRELID1/NOL3/GPX1/LMNA/FXN/CLU/BCL2L1/PAM16/PSMD10	10
BP	GO:0072604	interleukin-6 secretion	20/4749	48/18670	0.01011	0.07948	0.06466	TWIST1/IL1B/TLR8/IL17A/LGALS9/HMGB1/TNF/CD200/LILRA2/AIF1/IL27RA/C1QTNF3/IL17RC/SYT11/ZC3H12A/PAEP/RABGEF1/LILRA5/F2R/SPHK2	20
BP	GO:0030224	monocyte differentiation	16/4749	36/18670	0.01014	0.07948	0.06466	IRF7/VEGFA/CSF2/PPARG/CSF1R/FES/CSF1/ZBTB46/CD74/PIR/MT1G/JUN/IFI16/MYH9/ZFP36L1/FASN	16
BP	GO:0032733	positive regulation of interleukin-10 production	16/4749	36/18670	0.01014	0.07948	0.06466	CD83/IRF4/BCL3/TNFSF4/CLEC7A/LGALS9/HMGB1/TLR4/TIGIT/TLR2/NOD2/CD46/PIBF1/LILRA5/CD34/IL23A	16
BP	GO:1903131	mononuclear cell differentiation	16/4749	36/18670	0.01014	0.07948	0.06466	IRF7/VEGFA/CSF2/PPARG/CSF1R/FES/CSF1/ZBTB46/CD74/PIR/MT1G/JUN/IFI16/MYH9/ZFP36L1/FASN	16
BP	GO:0010761	fibroblast migration	17/4749	39/18670	0.01025	0.08027	0.0653	SDC4/RFFL/CORO1C/PML/BAG4/PAK1/ARID5B/C5orf30/PAK3/WDPCP/ARHGAP4/PRKCE/FER/TMEM201/PIP5K1A/TGFB1/ILK	17
BP	GO:0010952	positive regulation of peptidase activity	65/4749	197/18670	0.01032	0.08069	0.06564	GRAMD4/PPARG/NLRP3/CASP9/TTBK1/CTSH/GRN/PERP/CLEC7A/HIP1/PRELID1/LGALS9/PML/HMGB1/TNF/GSN/BAX/PMAIP1/ASPH/CARD9/STAT3/DAP/CYFIP2/P2RX1/CFLAR/ARRB1/VCP/MAPK12/BCL2L13/RPS3/HIP1R/PDCD5/CCK/FAS/BID/TNFRSF10B/MAP3K5/PINK1/BCAP31/KHDC1/BAK1/TANK/CTSD/RCN3/CASP8AP2/ACVR1C/ACER2/PSME2/IFI16/DAPK1/TRAF2/EIF2AK3/S100A8/ST18/F3/CIDEB/RIPK2/F2R/TNFSF10/AKIRIN2/CARD8/NDUFA13/BAD/FYN/SIRT1	65
BP	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	32/4749	86/18670	0.01036	0.08076	0.0657	SKIL/ICAM1/FAIM2/RFFL/LGALS3/ATF3/TNF/BAX/SERPINE1/PEA15/PMAIP1/GPX1/MOAP1/HMOX1/ARHGEF2/TMC8/CFLAR/FAS/BID/TNFRSF10B/STK3/FEM1B/CASP8AP2/PARK7/BCL2L1/BAG3/DAPK1/SFRP1/TRAF2/TNFSF10/TIMP3/BAD	32
BP	GO:0090305	nucleic acid phosphodiester bond hydrolysis	95/4749	302/18670	0.01036	0.08076	0.0657	ZC3H12C/RBBP8/EXO1/HELZ2/TREX1/DDB2/HMGB1/ZFP36/APEX2/ZC3H12D/BAX/FEN1/TSEN2/EXD3/NUDT16/XRN2/USB1/RNASE8/PELO/UBB/TSEN15/DCPS/ZRANB3/RFC2/RPS27A/ISG20/NOL9/POP5/DIS3L2/ERI3/UBA52/POLD4/PAN3/RNASEH2A/TSEN34/EDC4/ELAC1/ENDOD1/POLR2I/ERCC5/YBEY/POLE/ERCC2/NOP14/EXOSC2/GTF2H2/ANGEL1/RNASE6/DNASE1L2/APLF/UTP20/AEN/TSNAX/ZC3H12A/GTF2H1/BOP1/UTP23/SAMHD1/DFFB/ZNRD1/EME1/CNOT7/PPP1R8/DNA2/ABT1/ERN1/ENDOV/CPSF1/SMG6/TUT1/DICER1/ANKRD31/CPSF6/N4BP2/PAM16/RPP30/ZC3H12B/PNRC2/GTF2H5/HARBI1/XPA/RCL1/OGG1/WRN/NCBP2/FAN1/CUL4A/NMNAT1/DIS3L/CSTF3/ERCC1/EXOSC9/PIWIL4/RAD9A/TSN	95
BP	GO:0050715	positive regulation of cytokine secretion	48/4749	139/18670	0.01036	0.08076	0.0657	TWIST1/IL1B/MAPK11/NLRP3/CSF1R/IL10/TLR8/IL17A/GAPDH/HK1/LGALS9/HMGB1/TNF/TLR4/LILRA2/MMP12/IL4R/FFAR2/FCN1/SRC/CCL3/PTGER4/HAVCR2/SPTBN1/AIF1/TLR2/CD58/NOD2/LRP1/IL26/OSM/CADM1/C1QTNF3/IL17RC/IRF3/PAEP/LILRA5/IFNGR1/CD34/RIPK2/F2R/CLEC5A/CARD8/FZD5/GLMN/TRIM16/GATA3/P2RX7	48
BP	GO:0006289	nucleotide-excision repair	39/4749	109/18670	0.01047	0.08147	0.06628	RBBP8/DDB2/BRCA2/NEIL3/UBB/RFC2/RPS27A/CDK7/RAD23B/UBA52/ERCC8/POLD4/FANCC/POLR2I/ERCC5/POLE/ERCC2/RAD23A/GTF2H2/POLR2C/GTF2H1/ZNF830/XRCC1/PRPF19/MNAT1/USP45/CETN2/RAD52/POLR2J/GTF2H5/NEIL1/XPA/OGG1/COPS7A/FAN1/CUL4A/POLR2A/ERCC1/SIRT1	39
BP	GO:0032720	negative regulation of tumor necrosis factor production	27/4749	70/18670	0.01048	0.08147	0.06628	TWIST1/IL10/ACP5/PTPN6/BCL3/SIRPA/GPNMB/LGALS9/TLR4/FOXP3/TSPO/HAVCR2/AXL/CD33/IRAK3/IL27RA/DEFB114/SYT11/NFKBIL1/NLRC3/ZC3H12A/GHRL/ADIPOQ/IL4/CD34/DICER1/RARA	27
BP	GO:1903531	negative regulation of secretion by cell	69/4749	211/18670	0.01051	0.08164	0.06642	LIF/IL1B/NOTCH1/NLRP3/IL10/TLR8/PIM3/RAB11FIP1/NMB/CEACAM1/LGALS9/PML/TNF/TNFRSF4/ADRA2B/CD200/BTN2A2/TNFRSF21/FOXP3/ADTRP/IL1R2/RSAD2/FRMD4A/CCR2/HMOX1/ABAT/SYT4/PTGER4/ENY2/CRY1/ENHO/RSC1A1/EZR/ANXA5/PSMD9/IL27RA/OSM/GNAI2/CNR1/C1QTNF3/TLR6/RAB11FIP3/FMR1/ACVR1C/ANXA4/DEFB114/SYT11/VAMP3/TACR2/SRGN/ZC3H12A/RABGEF1/LILRA5/SFRP1/GHRL/ADIPOQ/CD34/TNFRSF1B/RAB11FIP5/F2R/P2RY1/HDAC9/BCR/CARD8/PFKL/NPFF/NDUFAF2/LRRC32/TRIM9	69
BP	GO:1902903	regulation of supramolecular fiber organization	109/4749	352/18670	0.01061	0.08227	0.06693	CDC42EP4/SDC4/PLEKHG2/ICAM1/CIT/FES/HCK/RAC1/CYFIP1/NF2/FHOD1/SNX9/CAPZB/GSN/HSPA1A/CTTN/MTOR/CKAP2/LDLR/MYADM/GPX1/RANGRF/BAG4/PSRC1/CDC42EP1/SWAP70/TMOD2/TENM1/ARHGEF5/NUMA1/CAPG/ARHGEF2/CLIP3/CORO1B/CLU/PTGER4/PDXP/AEBP1/TGFB3/WHAMMP3/PAK1/ADD3/PFN2/RPS3/HIP1R/ARHGAP35/S1PR1/ARPC1B/PAK3/TERF1/PREX1/PICK1/TMSB4Y/SPTBN1/FGF13/CORO1A/STMN1/CLASP2/CD47/VASP/TRIOBP/TWF2/LIMCH1/CFL1/COTL1/SPTAN1/S100A10/ARPC5/MKKS/ARAP1/MID1/LIMK1/CAPZA1/PARK7/TUBB4A/MAP1S/SH3PXD2B/PRKCE/TRIM54/ACTR3B/KANK3/WDR1/ALMS1/TMSB15A/VILL/SFRP1/FER/MAP1A/BMP10/ARF6/TPM1/ARHGAP18/AKAP13/APC/ARL2/SORBS3/WASF2/WHAMM/AP1AR/SLAIN2/ID1/C15orf62/SEMA5A/CDC42/WAS/CDH5/FMN1/ADD2/RAC3	109
BP	GO:0016311	dephosphorylation	144/4749	478/18670	0.01077	0.08344	0.06788	PKMYT1/PTPN13/ITGA2/WNK1/ACPP/DUSP10/DUSP4/LMTK3/CDKN3/PTPRF/ACP5/PTPN6/DLGAP5/PPM1N/DUSP6/PFKFB3/CPPED1/PPP1R14A/PTPN7/SBF1/LGALS3/CDC25A/YWHAE/MTMR3/PPP2R1A/PPP1R14B/TNF/NT5DC2/PPP1CB/PTPN1/CDC25C/SPPL3/PPTC7/SMG5/MTOR/BAG4/PTPN14/SWAP70/RIPK3/NUDT16/SRC/CDCA2/DAPP1/PPARGC1B/B3GAT3/DUSP5/PTBP1/INPP4A/SH2D4A/PDXP/PALD1/CD33/PFKFB4/URI1/BOD1/EPHX2/IGFBP3/HTT/PTPN4/PTPN9/SGPP1/PPP2R3C/EYA2/LHPP/PHACTR2/DUSP16/PINK1/MTMR9/PTPRC/IMPA2/TIMM50/ITGA1/DUSP23/DUSP22/TIPRL/SFI1/ACP6/PFKFB2/PPP2CA/LILRB2/FKBP1A/GBA/PTPN18/PPP1R3E/GNAI2/STYXL1/PPP1R16B/PPA2/CHP1/CAMTA1/PPP5C/PPM1G/FBXW11/RPRD1A/TAB1/DNAJC6/CAMK2G/CEP192/PTPRM/INPP1/PHLPP1/MGAT5/PSPH/PTPMT1/MTMR14/BTRC/PPP1R8/DUSP18/DUPD1/PPP1R26/ENOPH1/CDC14B/TSKS/PTPRS/NT5E/SMG6/SSH2/ELL/SEMA4D/ACP1/PPP2R3B/DUSP14/PPP1R15A/PPP1R9B/PPP6C/PPM1J/PPM1K/MYH6/SLC39A10/TGFB1/NT5C2/CNST/PPP1R12A/PGAM5/CDC25B/PPP1R2/CDH5/PPM1L/LPIN1/PPP6R1/PPP1R3B/PTP4A3/FAM220A/DUSP1	144
BP	GO:0032755	positive regulation of interleukin-6 production	35/4749	96/18670	0.01078	0.08344	0.06788	TWIST1/IL1B/TLR8/IL17A/IL1RN/TIRAP/TNFSF4/CLEC7A/LGALS9/HMGB1/TNF/TLR4/LILRA2/CARD9/STAT3/ARHGEF2/CD74/AIF1/TLR2/NOD2/LILRB2/TLR6/IL17RC/CYBA/PAEP/LILRA5/RIPK2/F2R/TYROBP/IL36A/AKIRIN2/TRAF6/PTAFR/P2RX7/IL37	35
BP	GO:1903845	negative regulation of cellular response to transforming growth factor beta stimulus	31/4749	83/18670	0.01083	0.08372	0.06811	SKIL/CD109/PMEPA1/SNX25/TGFB1I1/HSPA5/HSPA1A/SKI/DAND5/SMAD7/NKX2-1/CFLAR/UBB/TGFB3/PRDM16/SMAD6/RPS27A/SMURF1/FAM89B/UBA52/LEMD3/VASN/LDLRAD4/EID2/HTRA4/HTRA1/TGFB1/ZNF451/VEPH1/MIR17HG/SIRT1	31
BP	GO:0030111	regulation of Wnt signaling pathway	112/4749	363/18670	0.01088	0.08396	0.0683	EGR1/ZBED2/NOTCH1/ASPM/WNK1/SULF2/ITGA3/GSKIP/IGFBP4/CBFB/TLE4/DEPDC1B/PPP2R1A/LRRK1/SKI/UBE2B/TLE2/FOXP3/WNT10B/GID8/SRC/NKD1/TIAM1/CTHRC1/MBD2/LIMD1/PSMD8/VCP/DVL3/SFRP4/TMEM170B/PSMD1/PSMD2/FZD6/PTK7/WWTR1/FGF9/RBPJ/PSMF1/CDK14/ATP6V0C/PFDN5/FOXO1/LRP4/TCF7L2/SMARCA4/NXN/CYLD/STK3/TRPM4/TLE3/TLR2/DVL1/TNKS2/PPP2CA/PRDM15/PSMD9/LRP1/PSMA5/DDIT3/HMGXB4/WWOX/FAM53B/FRAT1/RAPGEF1/EMD/RNF213/PSMB7/INVS/RECK/PSMD5/ARNTL/YAP1/NRARP/ZNF703/SIAH2/TMEM198/GSK3A/PSME2/BTRC/DACT2/SFRP1/IFT80/RSPO3/PSMB5/ESR1/DLX5/MLLT3/BICC1/FZD9/MAD2L2/LRP6/PSMB4/GNAQ/PSMA3/CCNY/ZBED3/APC/AXIN2/PSMD10/TMEM64/SEMA5A/PSMB1/PSMD7/CSNK1G2/PSMB3/PSMC5/IGFBP6/TRABD2B/ILK/SPIN1/PSMD11	112
BP	GO:0050729	positive regulation of inflammatory response	52/4749	153/18670	0.01106	0.08523	0.06934	IL1B/IL18/IL21/ITGA2/ABCC1/CCL3L3/TTBK1/IL17A/GRN/C2CD4B/TNFSF4/CLEC7A/TNF/TLR4/SERPINE1/LDLR/FFAR2/PDCD4/CCR2/TGM2/BTK/CCL3/PTGER4/FFAR3/RPS19/HLA-E/CD47/CCL18/TLR2/NOD2/OSM/LTA/CNR1/TLR6/PARK7/IL17RC/NFKBIA/DEFB114/CEBPB/IDO1/KLKB1/NEAT1/LILRA5/S100A8/PLA2G2A/CD6/MGST2/NUPR1/TNFSF11/DDT/C2CD4A/IL23A	52
BP	GO:0002228	natural killer cell mediated immunity	25/4749	64/18670	0.01128	0.08635	0.07025	IL18/IL21/PTPN6/CEACAM1/LGALS9/ULBP2/RAET1E/TUBB/HLA-G/SH2D1A/HAVCR2/TUBB4B/CORO1A/HLA-E/MICA/LAG3/CADM1/RAB27A/UNC13D/CRK/LAMP1/ULBP1/KLRK1/CD96/PRDX1	25
BP	GO:0006360	transcription by RNA polymerase I	25/4749	64/18670	0.01128	0.08635	0.07025	UBTF/MTOR/SMARCB1/ATF4/CDK7/SMARCA4/NCL/DHX33/ERCC2/RASL11A/ERBB2/GTF2H2/GTF2H1/TAF1A/ZNRD1/DDX11/EIF2AK3/MNAT1/TAF1D/BAZ2A/GTF2H5/IPPK/POU4F1/PHF8/POLR1B	25
BP	GO:0048017	inositol lipid-mediated signaling	61/4749	184/18670	0.01135	0.08635	0.07025	TWIST1/IL18/TYRO3/PTPN13/NTRK2/CSF1R/CEP55/NTRK1/KLF4/PDGFA/PTPN6/IER3/CEACAM1/STAMBP/PLXNB1/TNF/GSN/NCS1/BTN2A2/ENTPD5/GAB2/PLEKHA1/SRC/HTR2A/NTRK3/IGF1R/PIK3R5/FLT3/EZR/PIP5K1B/PIRT/OSM/FLT1/PPP1R16B/UBE3A/ERBB2/NLRC3/FLT4/PIK3C3/SIRT2/LTK/F2R/ZFP36L1/SEMA4D/C1QBP/INSR/PIP4K2A/TNFAIP8L3/NCF1/NTF3/PIP4K2B/PPARD/PIP5K1A/PLCB1/HCST/MAPK1/PDGFB/GATA3/PTAFR/FYN/SIRT1	61
BP	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	11/4749	22/18670	0.01137	0.08635	0.07025	NOL9/ERI3/NOP14/EXOSC2/UTP20/BOP1/WDR12/ABT1/URB1/RCL1/EXOSC9	11
BP	GO:0006312	mitotic recombination	11/4749	22/18670	0.01137	0.08635	0.07025	BRCA2/RAD51/DMC1/ERCC2/XRCC3/XRCC1/RAD52/SMC5/ERCC1/TERF2/RAD54B	11
BP	GO:0009235	cobalamin metabolic process	11/4749	22/18670	0.01137	0.08635	0.07025	ABCC1/MMAB/TCN1/TCN2/CLYBL/CUBN/MMACHC/MTRR/CTRB1/MTR/LMBRD1	11
BP	GO:0019883	antigen processing and presentation of endogenous antigen	11/4749	22/18670	0.01137	0.08635	0.07025	CD1E/CD1A/CD1C/HLA-H/HLA-G/CD1B/CD74/CD1D/HLA-E/TAP1/ERAP1	11
BP	GO:0032656	regulation of interleukin-13 production	11/4749	22/18670	0.01137	0.08635	0.07025	NLRP3/IRF4/TNFSF4/LGALS9/TNFRSF21/HLA-E/PAEP/LILRA5/IL4/RARA/GATA3	11
BP	GO:0045624	positive regulation of T-helper cell differentiation	11/4749	22/18670	0.01137	0.08635	0.07025	CD86/IL18/NLRP3/CD80/TNFSF4/IL4R/HLX/IL12RB1/RIPK2/RARA/IL23A	11
BP	GO:1901798	positive regulation of signal transduction by p53 class mediator	11/4749	22/18670	0.01137	0.08635	0.07025	SPRED2/HEXIM1/ZNF385A/PMAIP1/MSX1/RPL26/UBB/RPL23/ATR/RPL11/ATM	11
BP	GO:0032048	cardiolipin metabolic process	8/4749	14/18670	0.01147	0.08635	0.07025	THEM5/PTPMT1/TAMM41/LCLAT1/TAZ/HADHB/CRLS1/PGS1	8
BP	GO:0035358	regulation of peroxisome proliferator activated receptor signaling pathway	8/4749	14/18670	0.01147	0.08635	0.07025	TWIST1/PTGIS/ASXL2/FABP5/STARD10/ASXL1/CITED2/SIRT1	8
BP	GO:0036295	cellular response to increased oxygen levels	8/4749	14/18670	0.01147	0.08635	0.07025	PPARG/ATP6V0D1/FOXO1/FAS/ATP6V1A/ATP6V1G1/ATG7/CCDC115	8
BP	GO:0046033	AMP metabolic process	8/4749	14/18670	0.01147	0.08635	0.07025	AK3/AMPD2/AK4/APRT/AMPD3/NT5E/AK1/AK2	8
BP	GO:0046479	glycosphingolipid catabolic process	8/4749	14/18670	0.01147	0.08635	0.07025	NAGA/NEU4/GM2A/NEU1/GBA/NEU3/GALC/HEXB	8
BP	GO:0046940	nucleoside monophosphate phosphorylation	8/4749	14/18670	0.01147	0.08635	0.07025	CMPK2/DTYMK/AK5/AK3/AK4/AK1/CMPK1/AK2	8
BP	GO:0051547	regulation of keratinocyte migration	8/4749	14/18670	0.01147	0.08635	0.07025	HBEGF/MMP9/MTOR/MAPRE2/IQSEC1/ARF6/HAS2/ADAM9	8
BP	GO:0070669	response to interleukin-2	8/4749	14/18670	0.01147	0.08635	0.07025	IL2RA/IL2RB/IL2RG/CDC5L/STAT5A/JAK3/SHC1/JAK1	8
BP	GO:0090151	establishment of protein localization to mitochondrial membrane	8/4749	14/18670	0.01147	0.08635	0.07025	TIMM10/PDCD5/TIMM22/ROMO1/TOMM22/AGK/NDUFA13/TIMM9	8
BP	GO:0097202	activation of cysteine-type endopeptidase activity	8/4749	14/18670	0.01147	0.08635	0.07025	PERP/ASPH/CYFIP2/BAK1/IFI16/CIDEB/RIPK2/BAD	8
BP	GO:0007229	integrin-mediated signaling pathway	37/4749	103/18670	0.0116	0.08708	0.07085	ITGA2/ITGA3/NEDD9/TSPAN32/HCK/ISG15/ZYX/CEACAM1/SEMA7A/ITGB8/ITGAX/SRC/DOCK1/CD177/LIMS1/ZNF304/ITGA1/CD47/ADAMTS13/ITGA6/LAT/FERMT3/THY1/ITGAE/TIMP1/ADAM15/CTNNA1/MYH9/TYROBP/ADAM11/ITGA2B/ADAMTS1/CDC42/ADAM9/LAMA5/NME2/ILK	37
BP	GO:1902106	negative regulation of leukocyte differentiation	37/4749	103/18670	0.0116	0.08708	0.07085	HMGB3/TRIB1/BCL6/CBFB/TNFSF4/CEACAM1/HMGB1/TLR4/PIAS3/FOXP3/CTLA4/ZBTB46/IL4R/SMAD7/HLA-G/LILRB4/CCL3/CD74/HLX/PGLYRP3/LAG3/TOB2/ERBB2/DTX1/ZC3H12A/TMEM176B/NRARP/SFRP1/ADIPOQ/IL4/ZNF675/CUL4A/JAK3/RARA/ZFPM1/TCTA/NME2	37
BP	GO:0051928	positive regulation of calcium ion transport	43/4749	123/18670	0.01167	0.08754	0.07122	HSPA2/CCR1/ANXA2P2/LGALS3/BAX/CXCL10/TRPC1/LILRA2/ANXA2/TSPO/HCRT/HOMER1/ATP2A1/CCL3/CAMK2A/KCNE3/SRI/PKD2/HTT/CCL2/ATP1B1/CASR/GSTO1/STAC3/CXCL9/BAK1/DRD1/STAC/THY1/CD19/SUMO1/NTSR1/LILRA5/LACRT/IL13/P2RX5/F2R/SPHK2/CACNB2/EHD3/FFAR1/PDGFB/P2RX7	43
BP	GO:0043244	regulation of protein complex disassembly	40/4749	113/18670	0.0117	0.08766	0.07131	CAPZB/TNF/GSN/CKAP2/ASPH/SWAP70/TMOD2/CAPG/ARHGEF2/PDXP/IGF1R/ADD3/FYCO1/UPF1/IRAK3/CALCOCO2/SPTBN1/FGF13/CLASP2/TRIOBP/TWF2/CFL1/SPTAN1/GBA/MID1/CAPZA1/MAP1S/TRIM54/WDR1/UVRAG/VILL/OGFOD1/SCAF4/GLE1/MAP1A/INSR/APC/PHF23/SEMA5A/ADD2	40
BP	GO:0051169	nuclear transport	107/4749	346/18670	0.01172	0.08772	0.07136	EGR2/IL1B/GTSE1/TXNIP/CDKN1A/SEC13/U2AF1/CAMK1/CDK5/YWHAE/RBM22/PML/KPNA2/NUP98/RGPD2/HTATIP2/SMG5/POLDIP3/MMP12/LMNA/PTPN14/STAT3/CSE1L/IWS1/SFN/HSPA9/RNPS1/RPS15/ENY2/SRSF4/FGF9/NUP153/TMCO6/UPF1/MAGOHB/SMURF1/TCF7L2/DUSP16/RPL23/ATXN1/ABCE1/STRADB/ALKBH5/SUPT6H/XPO6/DRD1/BANF1/NUP88/THOC3/NOLC1/RANBP6/FAM53B/CHP1/RSRC1/PARK7/EMD/EFCAB7/KPNA3/U2AF1L4/NFKBIA/CABP1/POM121C/NUP205/RAE1/ECT2/DDX20/ARNTL/NUP50/ZC3H12A/BAG3/DHX38/SDAD1/UPF3A/SNRPB/FAM53A/MAGOH/RAB23/POM121L2/CPSF1/UHMK1/SNRPD2/SMG6/GLE1/SNUPN/CPSF6/NUP93/AKAP13/DDX19A/LSG1/CDC40/RBM27/NUP35/SMN1/AAAS/NCBP2/TGFB1/PPP1R12A/CCHCR1/RGPD1/MAPK1/GEMIN5/NUP62/TNPO1/SEH1L/YTHDC1/BARD1/NXF3	107
BP	GO:0052548	regulation of endopeptidase activity	129/4749	425/18670	0.01179	0.08813	0.07169	FURIN/CD109/VEGFA/GRAMD4/PPARG/NLRP3/BIRC5/CASP9/ADORA2A/MICAL1/KLF4/TTBK1/SERPINB6/PTTG1/GAPDH/CTSH/PLAUR/PERP/RFFL/TIMP4/SERPINB8/TIMP2/CLEC7A/HIP1/PRELID1/MMP9/YWHAE/TP63/LGALS9/PML/HMSD/HMGB1/TNF/GSN/PROS1/NOL3/BAX/SERPINE1/TNFAIP8/PMAIP1/GPX1/ASPH/CARD9/STAT3/SORL1/DAP/CYFIP2/CST5/SRC/IFI6/PRDX3/CSTA/P2RX1/SFN/CFLAR/ARRB1/VCP/ATP13A2/CST3/BST2/BCL2L13/HERPUD1/PRDX5/RPS3/HIP1R/PSMF1/PDCD5/SPINT1/ITIH3/CCK/FAS/BID/TNFRSF10B/MAP3K5/BCAP31/SPOCK3/KHDC1/A2M/VTN/BAK1/CTSD/CASP8AP2/PARK7/TFAP2B/CRIM1/BCL2L12/ACVR1C/TIMP1/CD44/RECK/ACER2/UCHL5/SIAH2/BIRC3/PSME2/SERPING1/IFI16/LCN1/DAPK1/TRAF2/DNAJB6/EIF2AK3/S100A8/ST18/F3/CIDEB/RIPK2/F2R/POR/TNFSF10/CST6/CSN2/TIMP3/AKIRIN2/BIRC7/PSMA3/CARD8/SERPINA4/SERPINA10/ITIH6/CST1/CST2/NDUFA13/MGMT/TFPI/BAD/FYN/PAK2/SIRT1	129
BP	GO:0010565	regulation of cellular ketone metabolic process	60/4749	181/18670	0.01199	0.0893	0.07265	EGR1/TWIST1/IL1B/NR4A3/PPARG/PDPR/TREX1/CEACAM1/PPTC7/MTOR/ABCD1/ABCD2/PSMD8/ATCAY/FABP5/PSMD1/PSMD2/CD74/PSMF1/TYSND1/NQO1/PRKAB2/OAZ3/ADIPOR2/BHMT/SLC45A3/INSIG1/PSMD9/ATP2B4/ADIPOR1/PSMA5/PRKAG2/CNR1/PARK7/PSMB7/OAZ2/PIBF1/PRKCE/PSMD5/PSME2/ADM/ADIPOQ/CPT1A/PSMB5/DGAT2/ACACB/PSMB4/PSMA3/OAZ1/CYP7A1/PSMD10/PSMB1/PSMD7/PSMB3/RDH10/GSTZ1/PSMC5/TRIB3/PSMD11/SIRT1	60
BP	GO:0022408	negative regulation of cell-cell adhesion	60/4749	181/18670	0.01199	0.0893	0.07265	VEGFA/CD86/SDC4/WNK1/ADORA2A/IL10/KLF4/CD80/PTPN6/BCL6/IL1RN/CBFB/TNFSF4/LGALS3/GPNMB/CEACAM1/LGALS9/CD9/NF2/HMGB1/IL2RA/BTN2A2/TNFRSF21/FOXP3/ADTRP/MYADM/CTLA4/IL4R/SMAD7/SWAP70/ABAT/HLA-G/TIGIT/HAVCR2/CD74/CLEC4G/HLX/JAG1/DUSP22/LILRB2/ARG1/LAG3/EPB41L5/ERBB2/FXYD5/CEBPB/IDO1/DTX1/PDCD1LG2/ZC3H12A/NRARP/ZNF703/DLG5/ADIPOQ/PRNP/MAD2L2/TGFB1/GLMN/JAK3/LRRC32	60
BP	GO:0048015	phosphatidylinositol-mediated signaling	60/4749	181/18670	0.01199	0.0893	0.07265	TWIST1/IL18/TYRO3/PTPN13/NTRK2/CSF1R/CEP55/NTRK1/KLF4/PDGFA/PTPN6/IER3/CEACAM1/STAMBP/PLXNB1/TNF/GSN/NCS1/BTN2A2/ENTPD5/GAB2/PLEKHA1/SRC/HTR2A/NTRK3/IGF1R/PIK3R5/FLT3/EZR/PIP5K1B/PIRT/OSM/FLT1/PPP1R16B/UBE3A/ERBB2/NLRC3/FLT4/PIK3C3/SIRT2/LTK/F2R/ZFP36L1/SEMA4D/C1QBP/INSR/PIP4K2A/NCF1/NTF3/PIP4K2B/PPARD/PIP5K1A/PLCB1/HCST/MAPK1/PDGFB/GATA3/PTAFR/FYN/SIRT1	60
BP	GO:0061900	glial cell activation	23/4749	58/18670	0.01205	0.08968	0.07295	IL1B/ADORA2A/TTBK1/TLR8/GRN/CNTF/TNF/LDLR/CCL3/CLU/NAMPT/PTPRC/AIF1/TLR2/LRP1/TLR6/FPR2/JUN/IL13/IFNGR1/TYROBP/C1QA/ATM	23
BP	GO:1903046	meiotic cell cycle process	62/4749	188/18670	0.01214	0.09022	0.0734	ESPL1/LIF/ASPM/BUB1B/TTK/TOP2A/AURKA/HSPA2/TRIP13/CDC20/PTTG1/BUB1/CDC25A/NCAPD2/KIF18A/RAD54L/PPP2R1A/SYCE3/NUF2/SLC2A8/MSH6/FBXO43/BRCA2/UBE2B/PLK1/CDC25C/RAD51/MSX1/TDRD9/CKS2/FBXO5/DMC1/UBB/MND1/CCNE2/TERF1/TAF1L/HELQ/FIGNL1/TUBG2/NCAPH/REC8/STAG3/EME1/KLHDC3/SYCE2/SIRT2/MYH9/NCAPH2/TUBG1/UBR2/DMRTC2/ASZ1/ANKRD31/ATM/MLH3/PLCB1/NSUN2/RNF212/CDC25B/ERCC1/RAD54B	62
BP	GO:0060828	regulation of canonical Wnt signaling pathway	90/4749	286/18670	0.01218	0.09043	0.07357	EGR1/ZBED2/NOTCH1/ASPM/WNK1/SULF2/GSKIP/IGFBP4/TLE4/LRRK1/UBE2B/TLE2/WNT10B/GID8/SRC/NKD1/CTHRC1/LIMD1/PSMD8/VCP/DVL3/SFRP4/TMEM170B/PSMD1/PSMD2/FZD6/PTK7/WWTR1/FGF9/RBPJ/PSMF1/CDK14/PFDN5/FOXO1/LRP4/TCF7L2/CYLD/STK3/TRPM4/TLE3/DVL1/TNKS2/PRDM15/PSMD9/PSMA5/DDIT3/FAM53B/FRAT1/RAPGEF1/EMD/PSMB7/INVS/RECK/PSMD5/ARNTL/YAP1/NRARP/ZNF703/SIAH2/TMEM198/GSK3A/PSME2/BTRC/SFRP1/RSPO3/PSMB5/DLX5/MLLT3/BICC1/FZD9/MAD2L2/LRP6/PSMB4/GNAQ/PSMA3/CCNY/ZBED3/APC/AXIN2/PSMD10/TMEM64/SEMA5A/PSMB1/PSMD7/CSNK1G2/PSMB3/PSMC5/IGFBP6/ILK/PSMD11	90
BP	GO:0048193	Golgi vesicle transport	113/4749	368/18670	0.01228	0.09103	0.07406	KIF2C/SNX8/KIF4A/RAB31/KIF15/KIF23/SEC13/SURF4/KIF1C/RACGAP1/YIPF5/BBS2/RAB33A/KIF18A/GORASP1/SEC24D/CAPZB/CREB3L2/MCFD2/CTAGE4/PROS1/ANK1/KIF11/PROC/CUX1/F5/RANGRF/KLC1/SORL1/STX5/MYO5A/SEC16A/CENPE/SEC22C/KDELR2/VCP/KIF4B/CNIH2/WHAMMP3/GGA2/COG8/HTT/RABIF/DCTN5/RAB19/COG7/TMED3/PICK1/ANKRD28/SPTBN1/BCAP31/TBC1D20/PRKCI/VPS51/AP3D1/SPTAN1/LMF1/COPE/CEP19/INSIG1/TMED9/TRIM23/SNAP23/COG1/NRBP1/TMEM115/CAPZA1/KIF3C/GBF1/TMED10/VAMP3/CTSZ/TMED5/VPS52/LMAN2/AP4M1/CTAGE9/UVRAG/EXOC6B/TMED4/CORO7/YIF1A/ARF4/BGLAP/YIF1B/LAMP1/VTI1B/ACTR1A/COG3/RNF139/GOPC/TRAPPC4/RAB1A/RAB34/NAPG/ARL3/SEC22A/WHAMM/PROZ/AP1AR/PPP6C/EHD3/TMED1/COPG2/CNST/CCDC91/TMED6/TRAPPC12/PEF1/PPP6R1/RAB1B/RAB12/USO1	113
BP	GO:0001562	response to protozoan	12/4749	25/18670	0.01232	0.09103	0.07406	IL10/BATF/TSPAN32/IRF4/BCL3/GBP2/CLEC7A/IL4R/ARG1/CCDC88B/DEFA1B/GBP4	12
BP	GO:0060444	branching involved in mammary gland duct morphogenesis	12/4749	25/18670	0.01232	0.09103	0.07406	VDR/PML/CSF1/SRC/ETV5/KDM5B/LRP5L/DDR1/BTRC/ESR1/LRP6/TGFB1	12
BP	GO:0006913	nucleocytoplasmic transport	106/4749	343/18670	0.01232	0.09103	0.07406	EGR2/IL1B/GTSE1/TXNIP/CDKN1A/SEC13/U2AF1/CAMK1/CDK5/YWHAE/RBM22/PML/KPNA2/NUP98/RGPD2/HTATIP2/SMG5/POLDIP3/MMP12/LMNA/PTPN14/STAT3/CSE1L/IWS1/SFN/HSPA9/RNPS1/RPS15/ENY2/SRSF4/FGF9/NUP153/TMCO6/UPF1/MAGOHB/SMURF1/TCF7L2/DUSP16/RPL23/ATXN1/ABCE1/STRADB/ALKBH5/SUPT6H/XPO6/DRD1/NUP88/THOC3/NOLC1/RANBP6/FAM53B/CHP1/RSRC1/PARK7/EMD/EFCAB7/KPNA3/U2AF1L4/NFKBIA/CABP1/POM121C/NUP205/RAE1/ECT2/DDX20/ARNTL/NUP50/ZC3H12A/BAG3/DHX38/SDAD1/UPF3A/SNRPB/FAM53A/MAGOH/RAB23/POM121L2/CPSF1/UHMK1/SNRPD2/SMG6/GLE1/SNUPN/CPSF6/NUP93/AKAP13/DDX19A/LSG1/CDC40/RBM27/NUP35/SMN1/AAAS/NCBP2/TGFB1/PPP1R12A/CCHCR1/RGPD1/MAPK1/GEMIN5/NUP62/TNPO1/SEH1L/YTHDC1/BARD1/NXF3	106
BP	GO:0032677	regulation of interleukin-8 production	28/4749	74/18670	0.01236	0.09111	0.07413	IL1B/IL10/KLF4/BCL3/TLR8/TIRAP/CLEC7A/LGALS9/TNF/HSPA1A/TLR4/SERPINE1/FFAR2/FCN1/ARRB1/CD33/CD74/PTPRC/TLR2/CD58/NOD2/DDIT3/OTUD7B/TLR6/PARK7/ANXA4/ADIPOQ/F2R	28
BP	GO:0050710	negative regulation of cytokine secretion	28/4749	74/18670	0.01236	0.09111	0.07413	NLRP3/IL10/TLR8/PML/TNF/TNFRSF4/CD200/BTN2A2/TNFRSF21/FOXP3/IL1R2/PTGER4/EZR/IL27RA/C1QTNF3/TLR6/ANXA4/DEFB114/SYT11/SRGN/ZC3H12A/RABGEF1/LILRA5/GHRL/CD34/HDAC9/CARD8/LRRC32	28
BP	GO:0008154	actin polymerization or depolymerization	68/4749	209/18670	0.01244	0.09161	0.07453	CDC42EP4/PLEKHG2/ICAM1/CIT/MICAL1/HCK/RAC1/CYFIP1/MSRB1/SNX9/CAPZB/GSN/CTTN/MTOR/MYADM/BAG4/MICAL2/CDC42EP1/SWAP70/TMOD2/TENM1/CAPG/CORO1B/PDXP/WHAMMP3/ADD3/PFN2/HIP1R/ARHGAP35/ARPC1B/PAK3/PREX1/PICK1/TMSB4Y/SPTBN1/CORO1A/VASP/AIF1/TRIOBP/TWF2/CFL1/DIAPH3/COTL1/SPTAN1/ARPC5/MKKS/CAPZA1/PRKCE/ACTR3B/KANK3/WDR1/MICAL3/CORO7/TMSB15A/VILL/GHRL/FER/ARF6/ARHGAP18/PSTPIP2/WHAMM/AP1AR/C15orf62/SEMA5A/WAS/FMN1/ADD2/RAC3	68
BP	GO:0060326	cell chemotaxis	95/4749	304/18670	0.01251	0.092	0.07485	CXCL13/EGR3/NR4A1/HBEGF/IL1B/VEGFA/NOTCH1/HSD3B7/WNK1/ABCC1/IL10/CCL20/CCL3L3/RAC1/CXCR6/EPHB1/IL1RN/CH25H/CSF3R/CCL22/TIRAP/CCR1/DAPK2/CYP7B1/LGALS3/CCRL2/LGALS9/HMGB1/CSF1/CXCL10/SERPINE1/FFAR2/SWAP70/CCR6/CCR2/CCR4/ARHGEF5/SLC12A2/RHOG/TIAM1/PDE4D/CORO1B/CCL3/RAB13/PDE4B/CD74/CCR5/S1PR1/CCL2/PREX1/CCL17/RPS19/CORO1A/TRPM4/ITGA1/AIF1/CCL18/CXCL9/CXCL16/SBDS/FLT1/CXCL2/CXCL3/FPR2/GBF1/C3AR1/IL17RC/CRK/RAC2/CCR8/PADI2/RARRES2/S100A8/CKLF/IL36A/DEFA1B/C1QBP/CCL23/TNFSF11/CCL7/PPBP/THBS4/DDT/PIP5K1A/SEMA5A/CCL15/KLRK1/CXCR5/PDGFB/CCL27/CX3CR1/VEGFC/IL37/IL23A/DUSP1	95
BP	GO:0010770	positive regulation of cell morphogenesis involved in differentiation	52/4749	154/18670	0.01265	0.0929	0.07558	SKIL/VEGFA/MAP6/NTRK2/NEDD9/SRF/RAC1/PLXNB2/CYFIP1/PLXNB1/TNFRSF12A/LRP8/SEMA7A/CUX1/MYADM/ZFYVE27/TIAM1/AMIGO1/DOCK1/NTRK3/PLXNA1/PAK1/LIMS1/DOCK5/PAK3/PREX1/FBXO31/TRIOBP/TWF2/L1CAM/PLXND1/S100A10/LRP1/LIMK1/UNC13D/STK25/CRK/IST1/PARP6/SEMA4D/C1QBP/ARHGDIA/NEFL/RUFY3/SEMA5A/CDC42/HAS2/ADNP/TRPC5/GDI1/ILK/RAC3	52
BP	GO:0010950	positive regulation of endopeptidase activity	59/4749	178/18670	0.01266	0.0929	0.07558	GRAMD4/PPARG/NLRP3/CASP9/TTBK1/CTSH/PERP/CLEC7A/HIP1/PRELID1/LGALS9/PML/HMGB1/TNF/GSN/BAX/PMAIP1/ASPH/CARD9/STAT3/DAP/CYFIP2/P2RX1/ARRB1/VCP/BCL2L13/RPS3/HIP1R/PDCD5/CCK/FAS/BID/TNFRSF10B/MAP3K5/BCAP31/KHDC1/BAK1/CTSD/CASP8AP2/ACVR1C/ACER2/PSME2/IFI16/DAPK1/TRAF2/EIF2AK3/S100A8/ST18/F3/CIDEB/RIPK2/F2R/TNFSF10/AKIRIN2/CARD8/NDUFA13/BAD/FYN/SIRT1	59
BP	GO:0042273	ribosomal large subunit biogenesis	27/4749	71/18670	0.01289	0.09451	0.07689	RPL3/RPL10A/RPL35/RPL38/TRAF7/PPAN/RPL23A/RPL5/RPL26/RPL7/RPL6/NOL9/BRIX1/FASTKD2/MRPL20/RPL14/ZNHIT3/BOP1/RPL12/SDAD1/WDR12/RPL7A/MRTO4/MDN1/URB1/RPL11/MALSU1	27
BP	GO:0032647	regulation of interferon-alpha production	13/4749	28/18670	0.01298	0.09478	0.07711	IRF7/IL10/TLR8/HMGB1/IRF5/TLR4/MMP12/HAVCR2/NLRC3/IRF3/RIPK2/PTPRS/STAT1	13
BP	GO:0033598	mammary gland epithelial cell proliferation	13/4749	28/18670	0.01298	0.09478	0.07711	IQGAP3/BRCA2/BAX/GPX1/KDM5B/CEBPB/ZNF703/BTRC/ESR1/TNFSF11/MAPK1/CCND1/GATA3	13
BP	GO:0045408	regulation of interleukin-6 biosynthetic process	13/4749	28/18670	0.01298	0.09478	0.07711	IL1B/TIRAP/CLEC7A/TNF/CARD9/STAT3/CD74/TLR6/CEBPB/GHRL/TYROBP/TRAF6/PTAFR	13
BP	GO:0002534	cytokine production involved in inflammatory response	20/4749	49/18670	0.01307	0.09528	0.07751	IL17A/SIRPA/CLEC7A/TLR4/ABCD1/IL1R2/PDCD4/ABCD2/BAP1/C5orf30/NOD2/TLR6/IL17RC/IDO1/NLRC3/ZC3H12A/CHID1/CD6/CD96/SEH1L	20
BP	GO:1905897	regulation of response to endoplasmic reticulum stress	31/4749	84/18670	0.01307	0.09528	0.07751	SERINC3/HSPA5/HSPA1A/BAX/PTPN1/PMAIP1/SYVN1/CLU/USP19/HERPUD1/UBXN1/SGTA/UBE2G2/BCAP31/BAK1/DDIT3/PARK7/TXNDC12/EDEM2/BCL2L1/FICD/BRSK2/UBQLN2/EIF2AK3/ERN1/NUPR1/PPP1R15A/TMEM33/UBAC2/PDX1/SIRT1	31
BP	GO:0034614	cellular response to reactive oxygen species	56/4749	168/18670	0.01317	0.09586	0.07799	PPIF/CDK1/NR4A3/KLF2/IL10/KLF4/CCNA2/TREX1/SIRPA/MPV17/MMP9/TNF/MAP1LC3A/PLEKHA1/RIPK3/FXN/SRC/PRDX3/PPARGC1B/CFLAR/BTK/CDK2/AXL/PKD2/PRDX5/RPS3/NQO1/FOXO1/DHFR/CBX8/MAP3K5/PINK1/ROMO1/EZH2/FANCC/ARG1/PARK7/STK25/JUN/PPP5C/CRK/ECT2/MPO/TRAF2/FER/ERCC6L2/MTR/TPM1/CCS/ADPRHL2/NCF1/FOS/NET1/MAPK1/PRDX1/SIRT1	56
BP	GO:0001894	tissue homeostasis	73/4749	227/18670	0.01324	0.09625	0.0783	NCDN/VEGFA/NOTCH1/CSF1R/ACP5/SRF/RAC1/CTSH/TP53INP2/TFRC/BBS2/SPP1/CSF1/LRRK1/CDH23/TLR4/AKT3/BAX/TPP1/CCDC66/HOMER2/ACTG1/CCR2/SRC/PPARGC1B/HOMER1/SPATA7/GNAS/LYZ/WWTR1/RAB3D/S1PR1/MDM1/PRKCA/CORO1A/PIGR/USH1G/MKKS/NOD2/RCN3/NAPSA/PLEKHM1/CUBN/ZG16B/CA2/BBS12/RAC2/EPAS1/YAP1/IL7/TFF1/LACRT/ZNF830/LCN1/BGLAP/GIGYF2/TNFRSF11B/CD34/F2R/TRAF6/LIPA/TMEM119/TNFSF11/ZNF675/TMEM64/LDB1/P2RX7/ANKRD11/PRDX1/BARD1/RAC3/PIWIL4/ACTB	73
BP	GO:0006766	vitamin metabolic process	46/4749	134/18670	0.01333	0.09676	0.07872	VDR/IL1B/MTHFD2/MTHFD1L/ACPP/ABCC1/ACP5/VKORC1L1/TNF/TPK1/SLC2A3/VKORC1/VNN2/MMAB/SNAI1/SLC52A1/PDXP/TCN1/MTHFS/CYP26C1/TCN2/DHFR/GSTO1/SLC52A2/CLYBL/MTHFD1/RXRA/CYP27B1/CUBN/MMACHC/MTRR/PIAS4/CYP4F12/SLC23A2/GCLC/AASDHPPT/CTRB1/PCCB/MTR/LMBRD1/VNN1/CYP11A1/PPARD/RDH10/PDZD11/AKR1A1	46
BP	GO:0031648	protein destabilization	19/4749	46/18670	0.01334	0.09676	0.07872	CTSH/SIRT6/GSN/DERL1/PLK1/SRC/MYLIP/HTT/ISOC2/KDM8/PEX2/FBXW11/RAD23A/BTRC/PRNP/RNF139/ID1/FBXO4/SIRT1	19
BP	GO:0030149	sphingolipid catabolic process	14/4749	31/18670	0.0134	0.097	0.07891	NAGA/NEU4/PDXDC1/GM2A/NEU1/PPT1/GBA/ACER1/ACER2/ASAH2/ASAH2B/NEU3/GALC/HEXB	14
BP	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity	14/4749	31/18670	0.0134	0.097	0.07891	CDC6/PSRC1/CKS2/CCNB1/SRC/CKS1B/PKD2/CCNT2/CCNK/MNAT1/CCNY/PSMD10/CCND1/PDGFB	14
BP	GO:0006650	glycerophospholipid metabolic process	99/4749	319/18670	0.01342	0.09706	0.07896	TTC7A/MBOAT7/PTPN13/CSF1R/PDGFA/CPNE7/SBF1/PCTP/MFSD2A/MTMR3/SOCS2/SERINC3/AGPAT3/ABHD16A/PLBD1/TTC7B/LDLR/AGPAT2/THEM5/PLEKHA1/GDPD3/SOCS3/DGKZ/INPP4A/FABP5/PLA2G12A/HTR2A/PIGK/LPCAT2/SH3YL1/TMEM86B/PIGH/TMEM150A/PIK3R5/PITPNM1/GDPD1/PIKFYVE/DPM2/MTMR9/IMPA2/PLEKHA2/LPCAT3/PIP5K1B/ACP6/PIGQ/PI4K2A/PIGO/STARD10/SLA2/FPR2/PLEKHA8/AGAP2/LPCAT4/INPP1/PIGC/RAB38/PTPMT1/MTMR14/PLA2G15/PNPLA6/FAM126B/PRDX6/PIGW/PIK3C3/IP6K1/PLA2G2A/GDE1/TAMM41/LCLAT1/CETP/PIP4K2A/PIK3R4/PIGM/PTDSS1/PIGA/IP6K2/AGK/PIP4K2B/PLA2G5/ATM/TAZ/PIP5K1A/GPCPD1/PLCB1/ALDH5A1/GALR2/GPAT2/HADHB/PLB1/MBOAT1/PLEKHA3/PDGFB/IP6K3/PIGG/LPIN1/PIGT/CRLS1/PGS1/SLC44A1	99
BP	GO:0052547	regulation of peptidase activity	136/4749	452/18670	0.01344	0.09709	0.07899	FURIN/CD109/VEGFA/GRAMD4/PPARG/NLRP3/BIRC5/CASP9/ADORA2A/MICAL1/KLF4/TTBK1/SERPINB6/PTTG1/GAPDH/CTSH/PLAUR/GRN/PERP/RFFL/TIMP4/SERPINB8/TIMP2/CLEC7A/HIP1/PRELID1/MMP9/YWHAE/TP63/LGALS9/PML/HMSD/HMGB1/TNF/GSN/PROS1/NOL3/BAX/SERPINE1/TNFAIP8/PMAIP1/GPX1/ASPH/CARD9/STAT3/SORL1/DAP/CYFIP2/CST5/SRC/IFI6/PRDX3/CSTA/P2RX1/SFN/CFLAR/ARRB1/VCP/ATP13A2/CST3/MAPK12/BST2/BCL2L13/HERPUD1/PRDX5/RPS3/HIP1R/PSMF1/PDCD5/SPINT1/UBXN1/ITIH3/CCK/FAS/BID/TNFRSF10B/MAP3K5/PINK1/BCAP31/SPOCK3/KHDC1/A2M/VTN/BAK1/TANK/CTSD/RCN3/CASP8AP2/PARK7/TFAP2B/CRIM1/BCL2L12/ACVR1C/TIMP1/CD44/RECK/ACER2/UCHL5/SIAH2/BIRC3/PSME2/SERPING1/IFI16/LCN1/DAPK1/TRAF2/DNAJB6/EIF2AK3/S100A8/ST18/F3/CIDEB/RIPK2/F2R/POR/TNFSF10/CST6/CSN2/TIMP3/AKIRIN2/BIRC7/PSMA3/CARD8/SERPINA4/SERPINA10/ITIH6/CST1/CST2/NDUFA13/MGMT/TFPI/BAD/FYN/SSPO/PAK2/SIRT1	136
BP	GO:0009163	nucleoside biosynthetic process	18/4749	43/18670	0.01355	0.09761	0.07941	TYMP/DHODH/TK1/DTYMK/HPRT1/NME4/UPRT/NME3/MTAP/APRT/IMPDH1/GUK1/NT5E/CMPK1/CTPS2/UCK2/NME9/NME2	18
BP	GO:0045773	positive regulation of axon extension	18/4749	43/18670	0.01355	0.09761	0.07941	VEGFA/SRF/CYFIP1/TNFRSF12A/SEMA7A/ZFYVE27/NTRK3/PAK1/TWF2/L1CAM/LRP1/LIMK1/RUFY3/SEMA5A/ADNP/TRPC5/GDI1/ILK	18
BP	GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	17/4749	40/18670	0.01368	0.09785	0.07961	PTPN6/BCL6/TNFSF4/CEACAM1/FOXP3/IL4R/SMAD7/HLA-G/HAVCR2/CLEC4G/PTPRC/DUSP22/IL27RA/ARG1/IL7R/ZC3H12A/JAK3	17
BP	GO:0071887	leukocyte apoptotic process	37/4749	104/18670	0.01368	0.09785	0.07961	AURKB/IRF7/NR4A3/CASP9/IL10/PDCD1/BCL6/LGALS3/PRELID1/LGALS9/IL2RA/BAX/TNFRSF21/DOCK8/RIPK3/MERTK/RPS6/BTK/AXL/CD74/CCR5/DNAJA3/BAK1/CDKN2A/NOD2/IL7R/IDO1/IRF3/GIMAP8/RAPGEF2/TSC22D3/BIRC7/SLC39A10/JAK3/MIR17HG/P2RX7/SIRT1	37
BP	GO:0016569	covalent chromatin modification	142/4749	474/18670	0.01369	0.09785	0.07961	TWIST1/LIF/AURKB/IL1B/VEGFA/CDK1/AURKA/GTF3C4/DOT1L/RCOR1/IRF4/CCNA2/BCL6/SPI1/PHF19/UBE2A/UHRF1/CDK5/SFPQ/DPF3/ZNHIT1/SETD7/DDB2/SIRT6/SKI/BRCA2/PHF10/UBE2B/FOXP3/SMARCB1/LMNA/CRTC2/ING3/NAP1L2/ING5/RYBP/USP36/KANSL3/CCNB1/DTX3L/IWS1/MBD2/ARRB1/MORF4L2/KANSL1L/CDK2/PRMT7/MORC2/ENY2/SETD6/BAP1/KAT2A/PER2/UBE2N/PRDM16/ACTL6A/BCOR/SATB1/RNF40/EYA2/ELK4/CBX8/CARM1/TAF1L/ZNF304/PINK1/KDM5B/PRKCA/YEATS4/SUPT3H/EED/BRD4/EZH2/SUPT6H/TAF9B/MUC1/HSF4/DRD1/AICDA/ASXL1/TAF6L/RNF8/SIRT3/TAF10/KDM8/BRCC3/PCGF6/PPP5C/FMR1/MIER2/PCGF1/CHEK1/MCRS1/C6orf89/SAP30L/SETD1B/HELLS/MLLT6/PADI2/PCGF5/FBL/SIRT2/BRPF3/CAMK2D/TAF7/SETDB2/KAT6B/WDR5B/KDM5A/DPF1/UBR2/DMRTC2/TADA2A/PRKCB/BAZ2A/SPHK2/MTA1/WDR82/CTBP1/HDAC9/MBD1/ARID4A/MTA3/SIRT7/ATM/KDM4C/TGFB1/ZNF451/BMI1/PPHLN1/HDAC10/SETDB1/TRIM16/PHF8/LDB1/GATA3/CPA4/USP17L2/TADA1/RNF168/KAT6A/SIRT1	142
BP	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	30/4749	81/18670	0.0137	0.09785	0.07961	SKIL/CD109/PMEPA1/SNX25/TGFB1I1/HSPA5/HSPA1A/SKI/DAND5/SMAD7/NKX2-1/UBB/TGFB3/PRDM16/SMAD6/RPS27A/SMURF1/FAM89B/UBA52/LEMD3/VASN/LDLRAD4/EID2/HTRA4/HTRA1/TGFB1/ZNF451/VEPH1/MIR17HG/SIRT1	30
BP	GO:0034405	response to fluid shear stress	16/4749	37/18670	0.01372	0.09785	0.07961	CSF2/KLF2/KLF4/SMAD7/SRC/TGFB3/PKD2/SMAD6/ABCA1/CA2/CITED2/TGFB1/HAS2/ADAM9/P2RX7/SREBF2	16
BP	GO:0043029	T cell homeostasis	16/4749	37/18670	0.01372	0.09785	0.07961	CCNB2/LGALS9/IL2RA/BAX/PMAIP1/FOXP3/RIPK3/SIT1/RPS6/PPP2R3C/DNAJA3/CORO1A/TSC22D3/TGFB1/JAK3/P2RX7	16
BP	GO:0045730	respiratory burst	16/4749	37/18670	0.01372	0.09785	0.07961	DUSP10/HCK/RAC1/GRN/NCF4/CLEC7A/PGAM1/NOXA1/CYBB/RPS19/RAC2/MPO/CYBA/INSR/BCR/NCF1	16
BP	GO:0046006	regulation of activated T cell proliferation	16/4749	37/18670	0.01372	0.09785	0.07961	IL18/LGALS9/HMGB1/IL2RA/BTN2A2/FOXP3/RIPK3/RPS3/IL12RB1/ARG1/TNFSF9/PDCD1LG2/PRNP/HHLA2/LRRC32/IL23A	16
BP	GO:1903427	negative regulation of reactive oxygen species biosynthetic process	16/4749	37/18670	0.01372	0.09785	0.07961	IL10/ACP5/PTGIS/SIRPA/CTNS/ABCD1/STAT3/TSPO/ABCD2/CFLAR/ATP2B4/PARK7/ZC3H12A/CD34/KHSRP/FYN	16
BP	GO:0097530	granulocyte migration	48/4749	141/18670	0.01375	0.09796	0.0797	CXCL13/IL1B/IL1R1/CCL20/CCL3L3/RAC1/IL17A/IL1RN/CSF3R/CCL22/TIRAP/DAPK2/LGALS3/CSF1/CXCL10/PDE4D/CCL3/PTGER4/PDE4B/CD74/CD177/CCL2/PREX1/CCL17/ITGA1/CCL18/CXCL9/CXCL2/CXCL3/GBF1/C3AR1/IL17RC/RAC2/WDR1/CD99L2/RARRES2/S100A8/CKLF/UMOD/IL36A/C1QBP/CCL23/CCL7/PPBP/THBS4/CCL15/IL37/IL23A	48
BP	GO:0006595	polyamine metabolic process	9/4749	17/18670	0.01387	0.09821	0.0799	SMOX/SMS/SAT1/OAZ3/OAZ2/SATL1/DHPS/OAZ1/HDAC10	9
BP	GO:0007076	mitotic chromosome condensation	9/4749	17/18670	0.01387	0.09821	0.0799	CDCA5/NCAPG/NUSAP1/NCAPD2/NCAPH/PHF13/CHMP1A/NCAPH2/PHF23	9
BP	GO:0042753	positive regulation of circadian rhythm	9/4749	17/18670	0.01387	0.09821	0.0799	ADORA2A/ARNTL2/NKX2-1/RORC/FBXW11/ARNTL/NPS/BTRC/GHRL	9
BP	GO:0042994	cytoplasmic sequestering of transcription factor	9/4749	17/18670	0.01387	0.09821	0.0799	IL10/NFKBIE/TONSL/SRI/PKD2/NFKBIA/NFKBIL1/PSMD10/MXI1	9
BP	GO:0043373	CD4-positive, alpha-beta T cell lineage commitment	9/4749	17/18670	0.01387	0.09821	0.0799	BATF/IRF4/MTOR/FOXP3/STAT3/LY9/IL12RB1/ZFPM1/IL23A	9
BP	GO:0060263	regulation of respiratory burst	9/4749	17/18670	0.01387	0.09821	0.0799	DUSP10/RAC1/GRN/CLEC7A/NOXA1/RPS19/RAC2/INSR/BCR	9
BP	GO:0050707	regulation of cytokine secretion	68/4749	210/18670	0.01392	0.09842	0.08007	TWIST1/IL1B/MAPK11/NLRP3/CSF1R/IL10/TLR8/IL17A/GAPDH/HK1/LGALS9/PML/HMGB1/TNF/TNFRSF4/CD200/TLR4/BTN2A2/LILRA2/TNFRSF21/FOXP3/MMP12/IL1R2/IL4R/FFAR2/FCN1/SRC/CCL3/PTGER4/HAVCR2/SPTBN1/EZR/AIF1/TLR2/CD58/NOD2/LRP1/IL27RA/IL26/OSM/CADM1/C1QTNF3/TLR6/IL17RC/ANXA4/DEFB114/SYT11/SRGN/IRF3/ZC3H12A/PAEP/RABGEF1/LILRA5/IFNGR1/GHRL/CD34/RIPK2/TNFRSF1B/F2R/CLEC5A/HDAC9/CARD8/FZD5/GLMN/TRIM16/GATA3/P2RX7/LRRC32	68
BP	GO:0048608	reproductive structure development	130/4749	431/18670	0.01418	0.1002	0.0815	VDR/LIF/CCNF/VEGFA/NOTCH1/ASPM/E2F7/E2F8/CSF2/TYRO3/PPARG/ICAM1/FOSL1/IL10/NTRK1/PHLDA2/PTGIS/FANCG/CYP7B1/PLCD3/KIF18A/SPP1/TP63/PRDM1/PLK4/PTCH1/ADAM19/ST14/HSPA5/CRIP1/BRCA2/BAX/NASP/ITGB8/PLEKHA1/HYAL3/VASH1/SRC/SOCS3/NUDT1/SNAI1/NKX2-1/PRDX3/MERTK/RPS6/ARRB1/RRM1/DMC1/RAB13/UBB/AXL/ARID5B/FGF9/RBPJ/PKD2/CTSB/SPINT1/BIK/SDC1/TIFAB/PATZ1/KDM5B/TBC1D20/STK3/PCDH12/NRK/GREB1L/MKKS/FNDC3A/BAK1/WDR77/FEM1B/RXRA/WNT7A/SOX8/GDF7/ARID1A/BASP1/CYP27B1/UBE3A/NCOA4/REC8/GGNBP2/HS6ST1/WDR19/EPAS1/CITED2/CEBPB/IRX5/BCL2L1/TFEB/ADAM15/KRT19/BSG/ZNF830/CTNNA1/RBMY1B/SFRP1/DNAJB6/ADM/GHRL/RSPO3/ESR1/KDM5A/TNFSF10/ZFP36L1/LRP6/HOXA11/INSR/NUPR1/FGF8/EAF2/ARID4A/FZD5/ADAMTS1/ATM/PPARD/HTRA1/WDR48/ASB1/TMF1/RARA/MAPK1/CCND1/RDH10/PDGFB/GATA3/ERCC1/GCM1/SIRT1	130
BP	GO:0000018	regulation of DNA recombination	36/4749	101/18670	0.01441	0.1017	0.08272	IL10/BCL6/TNFSF4/TFRC/KPNA2/SIRT6/MSH6/UBE2B/FOXP3/RAD51/RAD51AP1/PARPBP/RMI2/TP53BP1/POLQ/MAGEF1/ZRANB3/PTPRC/FIGNL1/TIMELESS/SUPT6H/RECQL5/IL27RA/ERCC2/CHEK1/IL7R/APLF/WRAP53/TNFSF13/IL4/MAD2L2/HELB/WRN/TGFB1/WAS/TERF2	36
BP	GO:0072676	lymphocyte migration	39/4749	111/18670	0.01444	0.1017	0.08278	CXCL13/HSD3B7/WNK1/ICAM1/CCL20/CCL3L3/CH25H/CCL22/CYP7B1/CD200/CXCL10/ADTRP/DOCK8/CCR6/RIPK3/CCR2/GCSAM/SLC12A2/CCL3/S1PR1/CCL2/CCL17/AIF1/CCL18/CXCL16/IL27RA/CRK/CD99L2/PADI2/CKLF/DEFA1B/CCL23/GCSAML/CCL7/CCL15/KLRK1/ZAP70/GATA3/CCL27	39
BP	GO:0002260	lymphocyte homeostasis	24/4749	62/18670	0.01454	0.1024	0.08329	SKIL/SH2B2/CCNB2/LGALS9/IL2RA/BAX/PMAIP1/FOXP3/RIPK3/SIT1/RPS6/CD74/PPP2R3C/DNAJA3/CORO1A/LAT/BAK1/TNFRSF13B/TSC22D3/TGFB1/JAK3/MIR17HG/SLC40A1/P2RX7	24
BP	GO:0006767	water-soluble vitamin metabolic process	32/4749	88/18670	0.01491	0.1046	0.08513	MTHFD2/MTHFD1L/ACPP/ABCC1/ACP5/TPK1/SLC2A3/VNN2/MMAB/SLC52A1/PDXP/TCN1/MTHFS/TCN2/DHFR/GSTO1/SLC52A2/CLYBL/MTHFD1/CUBN/MMACHC/MTRR/SLC23A2/GCLC/AASDHPPT/CTRB1/PCCB/MTR/LMBRD1/VNN1/PDZD11/AKR1A1	32
BP	GO:0009791	post-embryonic development	32/4749	88/18670	0.01491	0.1046	0.08513	MYO7A/VEGFA/KLF4/CSRNP1/C12orf57/MYO1E/PRDM1/ATF5/BAX/MTOR/PLAGL2/PLEKHA1/SCN9A/GNAS/ARID5B/KDM5B/BAK1/SLC4A10/ACO1/ERCC2/ACVR2B/NDN/SCUBE1/GABRG2/GIGYF2/SERP1/PYGO1/FZD5/ATM/ALDH5A1/GATA3/ERCC1	32
BP	GO:0070125	mitochondrial translational elongation	32/4749	88/18670	0.01491	0.1046	0.08513	MRPL37/MRPL28/MRPL51/MRPS36/MRPL22/MRPL18/MRPS5/MRPS18C/MRPS11/MRPS6/MRPL20/MRPL50/MRPL36/MRPS2/MRPL35/MRPL27/MRPL15/MRPS25/MRPL34/MRPS14/MRPL13/PTCD3/GADD45GIP1/MRPL10/MRPL54/DAP3/MRPL2/MRPL39/MRPL43/TUFM/MRPL48/GFM1	32
BP	GO:0045071	negative regulation of viral genome replication	23/4749	59/18670	0.0151	0.1057	0.08603	IFIT1/ISG15/APOBEC3H/MX1/TNF/IFIT5/RSAD2/IFITM2/BST2/MORC2/OASL/ISG20/BANF1/IFITM3/AICDA/IFITM1/CCNK/ZC3H12A/OAS1/IFI16/ILF3/ZC3HAV1/SETDB1	23
BP	GO:0009408	response to heat	58/4749	176/18670	0.0151	0.1057	0.08603	CDKN1A/HSPA2/SEC13/DNAJA1/TGFB1I1/YWHAE/HSPA5/HSPA1A/NUP98/CXCL10/MTOR/BAG4/HMOX1/HSPA9/VCP/CAMK2A/MYOF/NUP153/EIF2B3/DNAJA3/HSF2/ST8SIA1/CHORDC1/HSF4/MICA/PIRT/NUP88/STAC/IRAK1/TP53INP1/SUMO1/CAMK2G/POM121C/NUP205/RAE1/NUP50/BAG3/HSPA6/BAG2/DNAJB6/CAMK2D/CD34/MAPKAPK2/HSPA1L/GCLC/ATR/HSPA14/NUP93/DNAJB4/NUP35/ATM/AAAS/MAPK1/NUP62/LRP11/SEH1L/MLST8/SIRT1	58
BP	GO:0006626	protein targeting to mitochondrion	35/4749	98/18670	0.01518	0.1059	0.08618	BNIP3L/TIMM17A/BAG4/GDAP1/TSPO/USP36/SAE1/TIMM10/BAP1/PDCD5/PARL/HPS4/BID/PINK1/TIMM22/TIMM50/ROMO1/GRPEL1/RAC2/BAG3/IMMP1L/GSK3A/RHOU/UBL5/MIPEP/HSPA1L/PAM16/TOMM22/AGK/FZD5/CHCHD4/NDUFA13/TIMM9/SREBF2/MGARP	35
BP	GO:0030038	contractile actin filament bundle assembly	35/4749	98/18670	0.01518	0.1059	0.08618	SDC4/SRF/RAC1/ZYX/NF2/FHOD1/MTOR/BAG4/SRC/ARHGEF5/TNFAIP1/ARRB1/PTGER4/TGFB3/PAK1/PFN2/S1PR1/STMN1/CLASP2/CD47/LIMCH1/S100A10/MKKS/ARAP1/LIMK1/SH3PXD2B/ALMS1/SFRP1/KCTD13/FAM171A1/TPM1/SORBS3/WASF2/CDC42/WAS	35
BP	GO:0043149	stress fiber assembly	35/4749	98/18670	0.01518	0.1059	0.08618	SDC4/SRF/RAC1/ZYX/NF2/FHOD1/MTOR/BAG4/SRC/ARHGEF5/TNFAIP1/ARRB1/PTGER4/TGFB3/PAK1/PFN2/S1PR1/STMN1/CLASP2/CD47/LIMCH1/S100A10/MKKS/ARAP1/LIMK1/SH3PXD2B/ALMS1/SFRP1/KCTD13/FAM171A1/TPM1/SORBS3/WASF2/CDC42/WAS	35
BP	GO:0009062	fatty acid catabolic process	38/4749	108/18670	0.01523	0.1061	0.08631	TWIST1/ABHD16A/MTOR/ADTRP/ABCD1/MECR/ABCD2/AIG1/SLC27A2/MCAT/GLYATL2/ACOX2/TYSND1/ACOT8/CNR1/AMACR/ETFA/PEX2/BDH2/PLA2G15/ABHD1/CYP4F12/ADIPOQ/CPT1A/SLC27A4/ACACB/ETFB/PCCB/ACAD11/ECI1/NUDT19/PECR/PPARD/PEX13/HADHB/SESN2/LPIN1/DECR2	38
BP	GO:0001890	placenta development	51/4749	152/18670	0.01524	0.1061	0.08631	VDR/LIF/CCNF/E2F7/E2F8/CSF2/PPARG/FOSL1/IL10/PHLDA2/PTGIS/PLCD3/SPP1/PRDM1/PLK4/ADAM19/ST14/ITGB8/VASH1/SOCS3/SNAI1/PRDX3/RPS6/RBPJ/PKD2/CTSB/SPINT1/STK3/PCDH12/NRK/RXRA/ARID1A/CYP27B1/GGNBP2/HS6ST1/EPAS1/CEBPB/TFEB/KRT19/BSG/DNAJB6/ADM/GHRL/RSPO3/ZFP36L1/FZD5/PPARD/HTRA1/MAPK1/PDGFB/GCM1	51
BP	GO:0061136	regulation of proteasomal protein catabolic process	60/4749	183/18670	0.01525	0.1061	0.08631	PBK/RNF144A/AURKA/TRIB1/CBFA2T3/HSPA1A/PLK2/ECSCR/PLK1/DET1/GPX1/WNT10B/SMAD7/RYBP/VCP/SDCBP/CLU/USP19/UBB/HERPUD1/PSMF1/N4BP1/UBXN1/RNF40/SGTA/PINK1/UBE2G2/PIAS1/BCAP31/RAD23B/DVL1/GBA/SUMO1/RNF19B/PARK7/FMR1/RAD23A/SCO1/EDEM2/USP5/UCHL5/GSK3A/PSME2/BRSK2/BTRC/UBQLN2/BAG2/SIRT2/ZFAND2A/GCLC/MAP1A/NUPR1/OSBPL7/RPL11/PSMD10/GLMN/TMF1/DNAJB2/UBAC2/TRIB3	60
BP	GO:0032543	mitochondrial translation	46/4749	135/18670	0.01534	0.1065	0.08665	MRPL37/MRPL28/MRPL51/MRPS36/MRPL22/MRPL18/MRPS5/MRPS18C/MRPS11/NSUN4/NOA1/MRPS6/FASTKD2/COA3/MRPL20/MRPL50/MRPL36/MRPS2/TRUB2/MRPL35/MRPL27/YARS2/MRPL15/MRPS25/MRPL34/LARS2/MRPS14/MRPL13/MTG1/PTCD3/FASTKD3/LRPPRC/GADD45GIP1/MRPL10/TRMT10C/MRPL54/DAP3/C1QBP/MRPL2/NGRN/MRPL39/MRPL43/TUFM/MRPL48/MALSU1/GFM1	46
BP	GO:0005996	monosaccharide metabolic process	91/4749	292/18670	0.01535	0.1065	0.08665	SLC35A2/TPI1/PHLDA2/IGFBP4/GAPDH/HK1/PFKFB3/CHST15/GLB1/ENO1/PGAM1/PFKP/ATF3/GPI/MPI/TNF/PPP1CB/HK2/SLC25A1/BRAT1/PMAIP1/MTOR/SDS/SLC2A3/CRTC2/SRC/PGM2L1/PKM/FABP5/ALDOC/PDHB/CRY1/PFKFB4/KAT2A/MAN2B1/ATF4/PER2/IGFBP3/FOXO1/GALK2/MDH2/RORC/GSTO1/FUCA2/GALK1/PFKFB2/SLC45A3/DLAT/ADIPOR1/ENO3/MAEA/PPP1R3E/C1QTNF3/TFAP2B/EPM2AIP1/GALM/PRKCE/OAS1/GSK3A/PHKG2/ALDOA/GHRL/GNMT/ADIPOQ/CPT1A/FGGY/DGAT2/SERP1/ACACB/SLC23A2/GCLC/FUT6/RPE/INSR/GALT/SLC35B4/PFKL/ALDOB/PGD/FUCA1/PPARD/ALDH5A1/CLK2/COX11/OMA1/SESN2/AKR1A1/PDX1/BAD/PPP1R3B/SIRT1	91
BP	GO:0050817	coagulation	105/4749	342/18670	0.01538	0.1066	0.08674	TYRO3/ITGA2/GNA15/ADORA2A/SH2B2/MICAL1/TSPAN32/SRF/PDGFA/RCOR1/RAC1/PTPN6/PLAUR/ENTPD1/DGKD/HPSE/ANXA2P2/CEACAM1/CD9/YWHAZ/CAPZB/ADRA2B/PROS1/TMPRSS6/TLR4/PROC/PLAU/SERPINE1/ADTRP/ANXA2/F5/CLIC1/ACTG1/VKORC1/DOCK8/PLAT/SRC/CBX5/DGKZ/MERTK/P2RX1/ABAT/F2RL2/ARRB1/GNAS/DOCK1/AXL/FZD6/P2RX6/CD177/ENTPD2/BLOC1S4/PIK3R5/AK3/HPS4/VAV2/PRKCA/ANXA5/ADAMTS13/A2M/VTN/PRCP/FERMT3/DTNBP1/RAB27A/CAPZA1/ENPP4/PRKCE/KLKB1/SCUBE1/FIBP/HBG1/TBXA2R/SERPING1/F3/CD34/MYH9/P2RX5/F2R/HBB/DOCK9/ITGA2B/PRKCB/PRKACB/P2RY1/C1QBP/GNAQ/TRPC7/PAPSS2/HMG20B/PROZ/SERPINA10/EHD3/CDC42/WAS/AKAP10/MAPK1/PDGFB/ZFPM1/GATA3/P2RX7/TFPI/FYN/ILK/ACTB	105
BP	GO:0031348	negative regulation of defense response	76/4749	239/18670	0.01545	0.1067	0.08683	PBK/TYRO3/PPARG/NLRP3/DUSP10/ADORA2A/IL10/ACP5/KLF4/TREX1/GRN/PTGIS/SIRPA/CEACAM1/LGALS9/IL2RA/CD200/PROC/FOXP3/LDLR/GPX1/ABCD1/MMP12/IL1R2/PARP14/PDCD4/SOCS3/SEC14L1/ABCD2/HLA-G/PTGER4/HAVCR2/TRAFD1/IRAK3/NPLOC4/C5orf30/CCK/PTPRC/RPS19/HLA-E/A2M/SCRIB/MICA/GBA/ARG1/C1QTNF3/FPR2/CRK/NLRC3/ZC3H12A/SAMHD1/RABGEF1/SERPING1/CNOT7/YTHDF3/IFI16/SIRT2/MMP26/GHRL/CHID1/ADIPOQ/IL4/TNFRSF1B/NT5E/PSMB4/C1QBP/SIGLEC10/BCR/TSPAN6/PPARD/HTRA1/METRNL/SIGLEC11/CDH5/CD96/GATA3	76
BP	GO:0002221	pattern recognition receptor signaling pathway	64/4749	197/18670	0.01545	0.1067	0.08683	IRF7/GRAMD4/TYRO3/IRF4/TLR8/TIRAP/TIFA/CLEC7A/UNC93B1/HMGB1/HSPA1A/TLR4/LILRA2/RSAD2/FFAR2/FCN1/SEC14L1/BTK/HAVCR2/UBB/TRIL/UBE2N/MAP2K6/CTSB/IRAK3/NPLOC4/RPS27A/PGLYRP3/LRRC14/CD300LF/CYLD/RFTN1/UBA52/TLR2/FLOT1/NOD2/TANK/IRAK1/TLR6/TAB1/NFKBIA/PRKCE/NFKBIL1/CYBA/IRF3/BIRC3/TNIP3/PIK3C3/S100A8/RIPK2/ESR1/MAPKAPK2/PTPRS/COLEC12/C1QBP/TRAF6/PIK3R4/TSPAN6/ANKRD17/ZCCHC3/USP17L2/PJA2/TRIM15/TRIM5	64
BP	GO:0006665	sphingolipid metabolic process	53/4749	159/18670	0.01553	0.1067	0.08683	SGMS1/NAGA/CTSA/NEU4/GLB1/SPTSSA/SGMS2/KDSR/PPP2R1A/SERINC3/TNF/PDXDC1/GM2A/NEU1/BAX/ITGB8/TECR/FA2H/P2RX1/PPT1/SGPP1/ST8SIA1/PRKD3/SUMF1/PPP2CA/GBA/ELOVL7/ACER1/ELOVL1/ACER2/PLA2G15/ASAH2/B4GALT5/ARV1/ALDH3B1/ASAH2B/ORMDL2/NEU3/TEX2/FUT6/GALC/SPHK2/HEXB/SUMF2/AGK/ST8SIA3/ALDH5A1/CERS3/CSNK1G2/ST6GALNAC6/PPM1L/P2RX7/ORMDL3	53
BP	GO:0032271	regulation of protein polymerization	70/4749	218/18670	0.01555	0.1067	0.08683	CDC42EP4/PLEKHG2/ICAM1/FES/HCK/RAC1/TTBK1/CYFIP1/SNX9/CAPZB/GSN/HSPA1A/CTTN/MTOR/MYADM/RANGRF/BAG4/PSRC1/CDC42EP1/TMOD2/TPPP3/TPPP/TENM1/NUMA1/CAPG/CLIP3/CORO1B/WHAMMP3/PAK1/ADD3/PFN2/RPS3/HIP1R/ARPC1B/PAK3/TERF1/PREX1/PICK1/TMSB4Y/PINK1/SPTBN1/CORO1A/STMN1/VASP/TRIOBP/TWF2/COTL1/SPTAN1/ARPC5/MKKS/CAPZA1/TUBB4A/PRKCE/ACTR3B/KANK3/TMSB15A/VILL/FER/ARF6/ARHGAP18/ARL2/WHAMM/AP1AR/SLAIN2/C15orf62/WAS/CDH5/FMN1/ADD2/RAC3	70
BP	GO:0016570	histone modification	136/4749	454/18670	0.01559	0.1067	0.08683	TWIST1/LIF/AURKB/IL1B/VEGFA/CDK1/AURKA/GTF3C4/DOT1L/RCOR1/IRF4/CCNA2/BCL6/SPI1/PHF19/UBE2A/UHRF1/CDK5/SFPQ/DPF3/ZNHIT1/SETD7/DDB2/SIRT6/SKI/BRCA2/PHF10/UBE2B/FOXP3/SMARCB1/LMNA/CRTC2/ING3/NAP1L2/ING5/RYBP/USP36/KANSL3/CCNB1/DTX3L/IWS1/ARRB1/MORF4L2/KANSL1L/CDK2/PRMT7/ENY2/SETD6/BAP1/KAT2A/PER2/UBE2N/PRDM16/ACTL6A/BCOR/SATB1/RNF40/EYA2/ELK4/CBX8/CARM1/TAF1L/ZNF304/PINK1/KDM5B/PRKCA/YEATS4/SUPT3H/EED/BRD4/EZH2/SUPT6H/TAF9B/MUC1/HSF4/DRD1/ASXL1/TAF6L/RNF8/SIRT3/TAF10/KDM8/BRCC3/PCGF6/PPP5C/FMR1/MIER2/PCGF1/CHEK1/MCRS1/C6orf89/SAP30L/SETD1B/MLLT6/PADI2/PCGF5/FBL/SIRT2/BRPF3/CAMK2D/TAF7/SETDB2/KAT6B/WDR5B/KDM5A/DPF1/UBR2/DMRTC2/TADA2A/PRKCB/BAZ2A/SPHK2/MTA1/WDR82/CTBP1/HDAC9/ARID4A/MTA3/SIRT7/ATM/KDM4C/TGFB1/ZNF451/BMI1/HDAC10/SETDB1/TRIM16/PHF8/LDB1/GATA3/CPA4/USP17L2/TADA1/RNF168/KAT6A/SIRT1	136
BP	GO:0006271	DNA strand elongation involved in DNA replication	10/4749	20/18670	0.01564	0.1067	0.08683	MCM4/FEN1/GINS2/GINS1/GINS4/MCM7/RNASEH2A/POLE/MCM3/DNA2	10
BP	GO:0043369	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment	10/4749	20/18670	0.01564	0.1067	0.08683	BATF/IRF4/MTOR/FOXP3/STAT3/LY9/CYLD/IL12RB1/ZFPM1/IL23A	10
BP	GO:0043371	negative regulation of CD4-positive, alpha-beta T cell differentiation	10/4749	20/18670	0.01564	0.1067	0.08683	BCL6/CBFB/TNFSF4/HMGB1/FOXP3/IL4R/SMAD7/HLX/ZC3H12A/JAK3	10
BP	GO:0046931	pore complex assembly	10/4749	20/18670	0.01564	0.1067	0.08683	NUP98/PLEKHA7/NUP153/TMEM170A/NUP205/NUP93/PDZD11/P2RX7/BAD/CCT3	10
BP	GO:0097734	extracellular exosome biogenesis	10/4749	20/18670	0.01564	0.1067	0.08683	SDC4/SNF8/SDCBP/ATP13A2/STAM/SDC1/HGS/RAB27A/CD34/CHMP2A	10
BP	GO:0072384	organelle transport along microtubule	31/4749	85/18670	0.01567	0.1067	0.08683	KIF23/KIF1C/UXT/BLOC1S6/BLOC1S1/UBB/CNIH2/SUN2/HTT/FYCO1/BLOC1S4/AP3D1/DTNBP1/KIF3C/MAP1S/AP3M2/SNAPIN/LAMP1/LRPPRC/ACTR1A/RHOT2/RAB1A/NEFL/TMEM201/AP3B2/COPG2/CDC42/UCHL1/SYNE2/SYBU/MGARP	31
BP	GO:0038110	interleukin-2-mediated signaling pathway	7/4749	12/18670	0.01568	0.1067	0.08683	IL2RA/IL2RB/IL2RG/STAT5A/JAK3/SHC1/JAK1	7
BP	GO:0060707	trophoblast giant cell differentiation	7/4749	12/18670	0.01568	0.1067	0.08683	LIF/E2F7/E2F8/PRDM1/PLK4/SOCS3/SNAI1	7
BP	GO:0070586	cell-cell adhesion involved in gastrulation	7/4749	12/18670	0.01568	0.1067	0.08683	WNK1/IL10/KLF4/IL1RN/MYADM/RIC8A/ADIPOQ	7
BP	GO:1904668	positive regulation of ubiquitin protein ligase activity	7/4749	12/18670	0.01568	0.1067	0.08683	UBE2C/CDC20/GORASP1/UBE2S/PLK1/CDC14B/RAB1A	7
BP	GO:2000105	positive regulation of DNA-dependent DNA replication	7/4749	12/18670	0.01568	0.1067	0.08683	E2F7/E2F8/CDT1/DBF4/DBF4B/CDK2/WIZ	7
BP	GO:2001198	regulation of dendritic cell differentiation	7/4749	12/18670	0.01568	0.1067	0.08683	LGALS9/HMGB1/ZBTB46/HLA-G/LILRB2/CEBPB/TMEM176B	7
BP	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	43/4749	125/18670	0.01569	0.1067	0.08683	GTSE1/E2F7/E2F8/CDK1/CDKN1A/AURKA/KANK2/CDKN2B/KLF4/ZNF385A/GPNMB/PML/E2F1/PLK2/BAX/BTN2A2/CDC25C/CDKN2C/GADD45A/CCNB1/SFN/RPL26/CDK2/RFWD3/CDK2AP2/PKD2/CCL2/FBXO31/CARM1/CNOT3/EZH2/TFDP2/MUC1/CDKN2A/MDM4/RBL2/CNOT7/GIGYF2/GML/CHEK2/ATM/ZNF655/CCND1	43
BP	GO:1903556	negative regulation of tumor necrosis factor superfamily cytokine production	27/4749	72/18670	0.01574	0.1069	0.08696	TWIST1/IL10/ACP5/PTPN6/BCL3/SIRPA/GPNMB/LGALS9/TLR4/FOXP3/TSPO/HAVCR2/AXL/CD33/IRAK3/IL27RA/DEFB114/SYT11/NFKBIL1/NLRC3/ZC3H12A/GHRL/ADIPOQ/IL4/CD34/DICER1/RARA	27
BP	GO:1900542	regulation of purine nucleotide metabolic process	48/4749	142/18670	0.01575	0.1069	0.08696	PPIF/CDK1/PDPR/SEC13/TREX1/PFKFB3/ENO1/PGAM1/CBFA2T3/SIRT6/NUP98/SLC25A23/ENTPD5/ABCD1/DNAJC30/STAT3/TSPO/CCNB1/VCP/HTR2A/PFKFB4/NUP153/GUCA1C/PINK1/DDIT4/PFKFB2/NUP88/PRKAG2/PARK7/POM121C/AK4/NUP205/RAE1/NUP50/IL4/ISCU/INSR/NUPR1/SPHK2/NUP93/NUP35/AAAS/TAZ/GSTZ1/NUP62/P2RX7/SEH1L/NCOR1	48
BP	GO:0002702	positive regulation of production of molecular mediator of immune response	34/4749	95/18670	0.01599	0.1084	0.08818	IL1B/IL18/NR4A3/NLRP3/IL1R1/HK1/TNFSF4/TFRC/MZB1/GPI/TNFRSF4/SEMA7A/TLR4/IL4R/RSAD2/FFAR2/HLA-G/TP53BP1/CD74/FFAR3/PTPRC/HLA-E/NOD2/IL18R1/IL13/TRAF2/TNFSF13/IL4/MAD2L2/KLK5/TRAF6/FZD5/TGFB1/GATA3	34
BP	GO:1901796	regulation of signal transduction by p53 class mediator	59/4749	180/18670	0.01611	0.109	0.08864	TWIST1/AURKB/TPX2/MAPK11/TP73/RBBP8/AURKA/TOP3A/EXO1/SPRED2/HEXIM1/DYRK3/ZNF385A/RFFL/CDK5/TP63/PML/RRM2B/PMAIP1/MSX1/ING5/RMI2/SNAI1/RPL5/RPL26/CDK2/UBB/CD74/TOPBP1/RFC2/PRKAB2/TAF1L/RPL23/TAF9B/MUC1/TP53INP1/TAF10/MDM4/BDKRB2/PRKAG2/BCL2L12/TAF11/CHEK1/CD44/BOP1/DNA2/TAF7/TAF6/ATR/CHEK2/RPL11/ATM/WRN/PSMD10/POU4F1/BARD1/KAT6A/RAD9A/SIRT1	59
BP	GO:0006968	cellular defense response	21/4749	53/18670	0.01617	0.109	0.08864	FOSL1/ADORA2A/CD300C/LSP1/CCR6/CCR2/HLA-G/SH2D1A/CCR5/CXCL9/LILRB2/MNDA/ITK/RAB23/TYROBP/UMOD/CLEC5A/ZNF148/NCF1/CX3CR1/KLRG1	21
BP	GO:0010043	response to zinc ion	21/4749	53/18670	0.01617	0.109	0.08864	CRIP1/MT1E/MT2A/TSPO/GGH/ATP13A2/MT1X/MT1H/HVCN1/ARG1/MT1G/CA2/BGLAP/S100A8/AANAT/MT1A/MT1B/MT1M/D2HGDH/P2RX7/MT1F	21
BP	GO:0030195	negative regulation of blood coagulation	21/4749	53/18670	0.01617	0.109	0.08864	PDGFA/PLAUR/ANXA2P2/CEACAM1/CD9/PROS1/TMPRSS6/PROC/PLAU/SERPINE1/ADTRP/ANXA2/PLAT/ABAT/ANXA5/VTN/KLKB1/SERPING1/CD34/PDGFB/TFPI	21
BP	GO:0045661	regulation of myoblast differentiation	21/4749	53/18670	0.01617	0.109	0.08864	NOTCH1/IL18/TNF/CXCL10/TRIP4/IGFBP3/CCL17/MAP3K5/CXCL9/DDIT3/SOX8/MBNL3/ZFP36L1/EID2B/HIF1AN/DLL1/PPARD/PLCB1/TGFB1/SRA1/ILK	21
BP	GO:0070228	regulation of lymphocyte apoptotic process	21/4749	53/18670	0.01617	0.109	0.08864	AURKB/IL10/PDCD1/BCL6/LGALS3/PRELID1/LGALS9/BAX/DOCK8/RIPK3/BTK/CD74/IL7R/IDO1/GIMAP8/TSC22D3/BIRC7/SLC39A10/JAK3/MIR17HG/P2RX7	21
BP	GO:0072329	monocarboxylic acid catabolic process	45/4749	132/18670	0.0162	0.109	0.08871	TWIST1/ABHD16A/MTOR/ADTRP/ABCD1/MECR/ABCD2/ABAT/IDUA/AIG1/SLC27A2/MCAT/GLYATL2/ACOX2/CYP26C1/TYSND1/ACOT8/CNR1/AMACR/ETFA/PEX2/BDH2/PLA2G15/ABHD1/FAH/CYP4F12/ADIPOQ/CPT1A/SLC27A4/ACACB/ETFB/PCCB/ACAD11/ECI1/NUDT19/PGD/PECR/PPARD/PEX13/ALDH5A1/HADHB/SESN2/AKR1A1/LPIN1/DECR2	45
BP	GO:0070227	lymphocyte apoptotic process	26/4749	69/18670	0.01646	0.1104	0.08979	AURKB/IL10/PDCD1/BCL6/LGALS3/PRELID1/LGALS9/IL2RA/BAX/TNFRSF21/DOCK8/RIPK3/RPS6/BTK/CD74/DNAJA3/BAK1/IL7R/IDO1/GIMAP8/TSC22D3/BIRC7/SLC39A10/JAK3/MIR17HG/P2RX7	26
BP	GO:0032637	interleukin-8 production	30/4749	82/18670	0.01647	0.1104	0.08979	IL1B/IL10/KLF4/BCL3/TLR8/TIRAP/CLEC7A/LGALS9/TNF/HSPA1A/TLR4/LILRA2/SERPINE1/FFAR2/FCN1/ARRB1/CD33/CD74/PTPRC/TLR2/CD58/NOD2/DDIT3/OTUD7B/TLR6/PARK7/ANXA4/ADIPOQ/F2R/RAB1A	30
BP	GO:0016054	organic acid catabolic process	86/4749	275/18670	0.01647	0.1104	0.08979	TWIST1/BCAT1/IL4I1/ABHD16A/DDAH2/MTOR/ADTRP/SDS/ABCD1/BCKDK/MPST/HYAL3/CARNS1/TST/MECR/ABCD2/GLS2/ABAT/GLDC/IDUA/AIG1/SLC27A2/OGDH/AMDHD1/MCAT/MTHFS/SARDH/HMGCL/GPT/GLYATL2/ACOX2/CYP26C1/CTH/TYSND1/GCAT/ACOT8/ENOSF1/GNPDA1/DLST/ATP2B4/ARG1/CNR1/CHP1/AMACR/ETFA/PEX2/CD44/MTRR/IDO1/BDH2/GLUD1/PLA2G15/ABHD1/FAH/CYP4F12/ADIPOQ/CPT1A/SLC27A4/ACACB/HGD/ETFB/HIBADH/PCCB/ACAD11/GPT2/HEXB/GUSB/ALDH7A1/AMT/ECI1/NUDT19/PGD/PECR/PPARD/PPM1K/PEX13/TGFB1/ALDH5A1/HADHB/GSTZ1/NAGK/ADHFE1/SESN2/AKR1A1/LPIN1/DECR2	86
BP	GO:0046395	carboxylic acid catabolic process	86/4749	275/18670	0.01647	0.1104	0.08979	TWIST1/BCAT1/IL4I1/ABHD16A/DDAH2/MTOR/ADTRP/SDS/ABCD1/BCKDK/MPST/HYAL3/CARNS1/TST/MECR/ABCD2/GLS2/ABAT/GLDC/IDUA/AIG1/SLC27A2/OGDH/AMDHD1/MCAT/MTHFS/SARDH/HMGCL/GPT/GLYATL2/ACOX2/CYP26C1/CTH/TYSND1/GCAT/ACOT8/ENOSF1/GNPDA1/DLST/ATP2B4/ARG1/CNR1/CHP1/AMACR/ETFA/PEX2/CD44/MTRR/IDO1/BDH2/GLUD1/PLA2G15/ABHD1/FAH/CYP4F12/ADIPOQ/CPT1A/SLC27A4/ACACB/HGD/ETFB/HIBADH/PCCB/ACAD11/GPT2/HEXB/GUSB/ALDH7A1/AMT/ECI1/NUDT19/PGD/PECR/PPARD/PPM1K/PEX13/TGFB1/ALDH5A1/HADHB/GSTZ1/NAGK/ADHFE1/SESN2/AKR1A1/LPIN1/DECR2	86
BP	GO:0002831	regulation of response to biotic stimulus	47/4749	139/18670	0.01664	0.1114	0.0906	IL1B/TRIB1/IFIT1/TSPAN32/GRN/CEACAM1/HMGB1/PQBP1/IL2RA/LILRA2/MMP12/DTX3L/SEC14L1/HAVCR2/PPP2R3C/CD180/NPLOC4/SIGIRR/PRKCA/TRIM44/IL12RB1/ARG1/RNF216/DEFB114/SYT11/NFKBIL1/CYBA/ZC3H12A/LACRT/BIRC3/SIRT2/RIPK2/LRSAM1/C1QBP/KLK5/TRAF6/TSPAN6/STAT1/CARD8/HTRA1/ANKRD17/SIGLEC11/ZCCHC3/USP17L2/TRIM15/IL23A/TRIM5	47
BP	GO:0007033	vacuole organization	54/4749	163/18670	0.01665	0.1114	0.0906	MYO7A/TREX1/GRN/TP53INP2/ANXA2P2/MTMR3/TPP1/MAP1LC3A/ANXA2/ATG9A/ATP13A2/PPT1/AMBRA1/PIKFYVE/HPS4/SMURF1/PINK1/CORO1A/TMEM106B/ABCA1/ULK1/GBA/TP53INP1/TMEM175/STX12/HOOK2/ATG2B/KIAA1324/TFEB/BAG3/SNAPIN/UBQLN2/NPRL3/RAB23/PIK3C3/ATG4B/NSFL1C/CLVS1/TMEM41B/LRSAM1/WDR45/NUPR1/HEXB/PIP4K2A/RAB1A/RAB34/RALB/PIP4K2B/PHF23/ATG7/CCDC115/P2RX7/RAB1B/NPRL2	54
BP	GO:0002931	response to ischemia	20/4749	50/18670	0.01668	0.1114	0.09067	EGR1/PPIF/CASP9/SQSTM1/CSF1R/FAIM2/EIF4EBP1/CSF1/HK2/NOL3/CAMK2A/PER2/MAP2K6/CASR/MAP3K5/PINK1/RNLS/UCHL1/P2RX7/CX3CR1	20
BP	GO:0110053	regulation of actin filament organization	82/4749	261/18670	0.01676	0.1118	0.09096	CDC42EP4/SDC4/PLEKHG2/ICAM1/CIT/HCK/RAC1/CYFIP1/NF2/FHOD1/SNX9/CAPZB/GSN/CTTN/MTOR/MYADM/BAG4/CDC42EP1/SWAP70/TMOD2/TENM1/ARHGEF5/CAPG/CORO1B/PTGER4/PDXP/TGFB3/WHAMMP3/PAK1/ADD3/PFN2/HIP1R/ARHGAP35/S1PR1/ARPC1B/PAK3/PREX1/PICK1/TMSB4Y/SPTBN1/CORO1A/STMN1/CLASP2/CD47/VASP/TRIOBP/TWF2/LIMCH1/CFL1/COTL1/SPTAN1/S100A10/ARPC5/MKKS/ARAP1/LIMK1/CAPZA1/SH3PXD2B/PRKCE/ACTR3B/KANK3/WDR1/ALMS1/TMSB15A/VILL/SFRP1/FER/ARF6/TPM1/ARHGAP18/SORBS3/WASF2/WHAMM/AP1AR/ID1/C15orf62/SEMA5A/CDC42/WAS/FMN1/ADD2/RAC3	82
BP	GO:2000117	negative regulation of cysteine-type endopeptidase activity	33/4749	92/18670	0.01684	0.1121	0.09118	VEGFA/BIRC5/ADORA2A/MICAL1/KLF4/PLAUR/RFFL/MMP9/YWHAE/NOL3/TNFAIP8/GPX1/SRC/IFI6/PRDX3/SFN/CFLAR/ARRB1/HERPUD1/PRDX5/PARK7/TFAP2B/BCL2L12/CD44/SIAH2/BIRC3/IFI16/DNAJB6/POR/CSN2/BIRC7/CARD8/PAK2	33
BP	GO:0009147	pyrimidine nucleoside triphosphate metabolic process	11/4749	23/18670	0.01687	0.1121	0.09118	DCTPP1/TYMS/CMPK2/DTYMK/AK3/NME4/NME3/CTPS2/UCK2/NME9/NME2	11
BP	GO:0032373	positive regulation of sterol transport	11/4749	23/18670	0.01687	0.1121	0.09118	ABCG1/ANXA2P2/PTCH1/ANXA2/ABCA1/LRP1/ABCB4/NFKBIA/ADIPOQ/LDLRAP1/SIRT1	11
BP	GO:0032376	positive regulation of cholesterol transport	11/4749	23/18670	0.01687	0.1121	0.09118	ABCG1/ANXA2P2/PTCH1/ANXA2/ABCA1/LRP1/ABCB4/NFKBIA/ADIPOQ/LDLRAP1/SIRT1	11
BP	GO:0006790	sulfur compound metabolic process	113/4749	372/18670	0.01705	0.1132	0.09208	ACPP/MICAL1/SUOX/CHAC1/HS3ST3B1/PDPR/CHST15/GLB1/ACSM3/ACOT11/GAMT/SLC25A1/ETHE1/CHPF2/CTNS/TPK1/TECR/GPX1/ABCD1/THEM5/MPST/CHAC2/PMVK/IDS/MICAL2/FXN/TST/SCD/GGT1/SMS/OGN/HSPA9/FAR2/CSGALNACT1/IDUA/NDOR1/OGDH/PDHB/IBA57/ACBD6/PPT1/HMGCL/SLC35D2/ACSL1/PDHX/SLC35D1/NUBP1/CTH/OPLAH/GSTO1/B3GALT6/HSD17B8/ACOT8/LIAS/MRI1/B3GNT2/SLC35B2/SPOCK3/CHST7/DLST/MTHFD1/BHMT/DLAT/GGTLC2/SP1/GPX4/PARK7/ELOVL7/MMACHC/MTRR/MTAP/DSEL/ST3GAL3/GSTM1/ELOVL1/SULT6B1/ACSL4/CHPF/METTL16/B4GALT5/GNMT/GSTT1/ENOPH1/ISCU/OXSM/DGAT2/STAT5A/MGST2/ACACB/GCLC/GGT7/ACSS1/FASN/PCCB/MTR/HEXB/GAL3ST4/CHST13/MGST3/GSTK1/PAPSS2/NFS1/ISCA2/GSS/XYLT1/MPC1/ALDH5A1/ACOT6/GSTZ1/B4GALT4/PDZD11/AKR1A1/BHMT2	113
BP	GO:0044106	cellular amine metabolic process	44/4749	129/18670	0.01712	0.1135	0.09237	SMOX/SMS/ABAT/MOXD1/PSMD8/ATCAY/PSMD1/PSMD2/HPRT1/SARDH/PSMF1/GDPD1/NQO1/SAT1/OAZ3/BHMT/DRD1/PSMD9/ATP2B4/PSMA5/PARK7/PSMB7/OAZ2/PSMD5/IDO1/TPH1/PSME2/SATL1/PSMB5/GDE1/AANAT/DHPS/PSMB4/PSMA3/ALDH7A1/OAZ1/PSMD10/PSMB1/PSMD7/PSMB3/HDAC10/PSMC5/PSMD11/SLC44A1	44
BP	GO:1901659	glycosyl compound biosynthetic process	19/4749	47/18670	0.01716	0.1137	0.09248	TYMP/DHODH/TK1/TRMT12/DTYMK/HPRT1/NME4/UPRT/NME3/MTAP/APRT/IMPDH1/GUK1/NT5E/CMPK1/CTPS2/UCK2/NME9/NME2	19
BP	GO:0006110	regulation of glycolytic process	29/4749	79/18670	0.0173	0.1143	0.09302	SEC13/TREX1/PFKFB3/PGAM1/CBFA2T3/SIRT6/NUP98/ENTPD5/STAT3/HTR2A/PFKFB4/NUP153/DDIT4/PFKFB2/NUP88/PRKAG2/POM121C/NUP205/RAE1/NUP50/INSR/NUPR1/NUP93/NUP35/AAAS/NUP62/P2RX7/SEH1L/NCOR1	29
BP	GO:0030193	regulation of blood coagulation	29/4749	79/18670	0.0173	0.1143	0.09302	PDGFA/PLAUR/HPSE/ANXA2P2/CEACAM1/CD9/PROS1/TMPRSS6/TLR4/PROC/PLAU/SERPINE1/ADTRP/ANXA2/VKORC1/PLAT/ABAT/PRKCA/ANXA5/VTN/ENPP4/KLKB1/TBXA2R/SERPING1/F3/CD34/F2R/PDGFB/TFPI	29
BP	GO:0051017	actin filament bundle assembly	51/4749	153/18670	0.01734	0.1144	0.09305	SDC4/FSCN1/NEDD9/SRF/MARCKS/RAC1/ZYX/NF2/FHOD1/MTOR/BAG4/SWAP70/SRC/ARHGEF5/TNFAIP1/CORO1B/ARRB1/PLS1/PTGER4/PDXP/TGFB3/PAK1/ADD3/PFN2/S1PR1/EZR/STMN1/CLASP2/CD47/AIF1/LIMCH1/ACTN4/S100A10/MKKS/ARAP1/LIMK1/SH3PXD2B/SHROOM1/RHOF/ALMS1/SFRP1/KCTD13/FAM171A1/TPM1/AIF1L/SORBS3/WASF2/ID1/CDC42/WAS/ADD2	51
BP	GO:0062013	positive regulation of small molecule metabolic process	51/4749	153/18670	0.01734	0.1144	0.09305	TWIST1/IL1B/CDK1/NR4A3/PPARG/ABCG1/PFKFB3/ENO1/TNF/ENTPD5/PMAIP1/ABCD1/STAT3/CCNB1/SRC/ABCD2/VCP/HTR2A/CD74/PFKFB4/KAT2A/GUCA1C/FOXO1/PINK1/PFKFB2/SLC45A3/PPP1R3E/NTSR1/PARK7/EPM2AIP1/PRKCE/PHKG2/ADM/ADIPOQ/IL4/CPT1A/ISCU/POR/DGAT2/LDLRAP1/P2RY1/INSR/NUPR1/TAZ/CYP7A1/HAS2/RDH10/PDGFB/PTAFR/P2RX7/SIRT1	51
BP	GO:0060562	epithelial tube morphogenesis	99/4749	322/18670	0.01746	0.1151	0.09362	VDR/TWIST1/VEGFA/NOTCH1/SDC4/STIL/MTHFD1L/CSF1R/LUZP1/SRF/KIF20B/PLXNB2/CTSH/PTCH1/PML/ST14/SEMA4C/TNF/CSF1/SIRT6/SKI/CXCL10/DCHS1/ITGAX/MICAL2/RNF207/SRC/ETV5/NKX2-1/ALX1/CTHRC1/DVL3/PAK1/FZD6/PTK7/KAT2A/KLHL3/RBPJ/PKD2/LMO4/ARHGAP35/SPINT1/PRKX/STARD13/HOXB7/CASR/KDM5B/STK3/LIAS/SALL4/TBX6/VASP/IFT122/CFL1/PLXND1/GREB1L/TCTN1/DVL1/TIMELESS/MTHFD1/SCRIB/MKKS/IFT172/RALA/SOX8/GDF7/ARID1A/CTSZ/LRP5L/SOX11/YAP1/NRARP/DDR1/BTRC/SHROOM3/DLG5/SFRP1/ADM/SETDB2/ESR1/LRP6/PRKACB/HOXA11/TRAF6/FGF8/MED12/PBX1/DLL1/TGFB1/KIF26B/TCAP/GLMN/RARA/RDH10/FMN1/LAMA5/ESRP2/GATA3/ILK	99
BP	GO:0051193	regulation of cofactor metabolic process	41/4749	119/18670	0.01751	0.1153	0.09378	RAC1/PDPR/SEC13/TREX1/PFKFB3/PGAM1/CBFA2T3/SIRT6/NOXA1/NUP98/PPTC7/CTNS/ENTPD5/STAT3/HTR2A/PFKFB4/NUP153/PINK1/DDIT4/CLYBL/PFKFB2/NUP88/PRKAG2/POM121C/RAC2/NUP205/RAE1/ZNF205/NUP50/NNT/INSR/NUPR1/NUP93/NUP35/AAAS/GSTZ1/NUP62/P2RX7/SEH1L/NCOR1/FYN	41
BP	GO:0046688	response to copper ion	18/4749	44/18670	0.01758	0.1156	0.09406	CDK1/ICAM1/S100A13/MAP1LC3A/MT1E/MT2A/PAM/AQP2/MT1X/MT1H/MT1G/PARK7/PRNP/AANAT/MT1A/MT1B/MT1M/MT1F	18
BP	GO:1903305	regulation of regulated secretory pathway	53/4749	160/18670	0.0176	0.1156	0.09406	NOTCH1/ADORA2A/MICAL1/FES/RIMS3/CDK5/CEACAM1/LGALS9/SYN1/NCS1/CHRNA5/GAB2/HYAL3/IL4R/CCR2/HMOX1/P2RX1/SYT4/HTR2A/CAMK2A/CD177/RAB3D/PFN2/APBA2/STX1B/DVL1/DRD1/DTNBP1/GNAI2/RAB27A/WNT7A/CNR1/UNC13D/FMR1/SYT11/RAC2/RABGEF1/IL13/SNAPIN/NAPB/LAMP1/FER/DOC2B/PRKCB/P2RY1/RAB15/SPHK2/CACNB2/BCR/FBXL20/SYT15/PTAFR/TRIM9	53
BP	GO:0001916	positive regulation of T cell mediated cytotoxicity	12/4749	26/18670	0.01767	0.1159	0.09426	CD1E/CD1A/CD1C/HLA-H/HLA-G/CD1B/CD1D/PTPRC/HLA-E/IL12RB1/P2RX7/IL23A	12
BP	GO:0002360	T cell lineage commitment	12/4749	26/18670	0.01767	0.1159	0.09426	BATF/IRF4/MTOR/FOXP3/STAT3/LY9/CYLD/IL12RB1/IL7/RAG2/ZFPM1/IL23A	12
BP	GO:0097306	cellular response to alcohol	32/4749	89/18670	0.01773	0.1161	0.09446	PPARG/KLF2/KLF4/SPI1/TNFSF4/PTCH1/LRP8/CYBB/GRAMD1C/RAD51/LANCL2/PTGER4/ADCY6/KCNMB1/GRAMD1B/KLF9/ABCA1/RECQL5/TP53INP1/PRKCE/PTGER2/ADCY3/ADAM15/CTNNA1/SFRP1/MAP4K1/LRP6/OSBPL7/SPHK2/CCL7/GRAMD1A/CYP7A1	32
BP	GO:0061458	reproductive system development	130/4749	434/18670	0.01774	0.1161	0.09446	VDR/LIF/CCNF/VEGFA/NOTCH1/ASPM/E2F7/E2F8/CSF2/TYRO3/PPARG/ICAM1/FOSL1/IL10/NTRK1/PHLDA2/PTGIS/FANCG/CYP7B1/PLCD3/KIF18A/SPP1/TP63/PRDM1/PLK4/PTCH1/ADAM19/ST14/HSPA5/CRIP1/BRCA2/BAX/NASP/ITGB8/PLEKHA1/HYAL3/VASH1/SRC/SOCS3/NUDT1/SNAI1/NKX2-1/PRDX3/MERTK/RPS6/ARRB1/RRM1/DMC1/RAB13/UBB/AXL/ARID5B/FGF9/RBPJ/PKD2/CTSB/SPINT1/BIK/SDC1/TIFAB/PATZ1/KDM5B/TBC1D20/STK3/PCDH12/NRK/GREB1L/MKKS/FNDC3A/BAK1/WDR77/FEM1B/RXRA/WNT7A/SOX8/GDF7/ARID1A/BASP1/CYP27B1/UBE3A/NCOA4/REC8/GGNBP2/HS6ST1/WDR19/EPAS1/CITED2/CEBPB/IRX5/BCL2L1/TFEB/ADAM15/KRT19/BSG/ZNF830/CTNNA1/RBMY1B/SFRP1/DNAJB6/ADM/GHRL/RSPO3/ESR1/KDM5A/TNFSF10/ZFP36L1/LRP6/HOXA11/INSR/NUPR1/FGF8/EAF2/ARID4A/FZD5/ADAMTS1/ATM/PPARD/HTRA1/WDR48/ASB1/TMF1/RARA/MAPK1/CCND1/RDH10/PDGFB/GATA3/ERCC1/GCM1/SIRT1	130
BP	GO:0019395	fatty acid oxidation	35/4749	99/18670	0.01787	0.1168	0.09501	TWIST1/NR4A3/PPARG/MTOR/ABCD1/MECR/ABCD2/SLC27A2/MCAT/ACOX2/TYSND1/ACOT8/ADIPOR2/ADIPOR1/PRKAG2/CNR1/AMACR/ETFA/PEX2/BDH2/ADIPOQ/CPT1A/POR/DGAT2/ACACB/ETFB/ACAD11/ECI1/PECR/PPARD/CYP4V2/PEX13/HADHB/SESN2/DECR2	35
BP	GO:0016579	protein deubiquitination	88/4749	283/18670	0.01789	0.1168	0.09503	CDK1/NLRP3/CDC20/CCNA2/CLSPN/USP35/TFPT/CDC25A/STAMBP/DDB2/USP53/USP9X/SMAD7/ASXL2/USP36/OTUB2/PSMD8/VCP/ENY2/STAM/USP19/UBB/PSMD1/PSMD2/BAP1/KAT2A/MBD6/ACTL6A/PSMF1/MBD5/UBXN1/RPS27A/CYLD/RAD23B/SUPT3H/UBA52/USP40/USP54/TAF9B/RCE1/PSMD9/TANK/ASXL1/PSMA5/OTUD7B/HGS/TAF10/MDM4/BRCC3/PARK7/PSMB7/TAB1/USP44/NFKBIA/MCRS1/RAD23A/PSMD5/USP5/UCHL5/ZC3H12A/UCHL3/SIAH2/BIRC3/PSME2/TNIP3/SMAD1/TRAF2/PSMB5/ESR1/USP45/PSMB4/TRAF6/PSMA3/APC/JOSD1/WDR48/PSMD10/PSMB1/PSMD7/PSMB3/SPATA2/UCHL1/PSMC5/GATA3/USP17L2/BARD1/PSMD11/ACTB	88
BP	GO:0097178	ruffle assembly	17/4749	41/18670	0.01794	0.1169	0.09507	ICAM1/RAC1/CYFIP1/CORO1C/BAG4/RHOG/SH3YL1/PFN2/EPS8L2/WDPCP/AIF1/PLEKHM1/ARF6/AIF1L/PIP5K1A/USP17L2/ARHGEF26	17
BP	GO:1902893	regulation of pri-miRNA transcription by RNA polymerase II	17/4749	41/18670	0.01794	0.1169	0.09507	IL10/SRF/SPI1/STAT3/NR3C1/LILRB4/SMAD6/SMARCA4/ATOH8/GNL3/JUN/SMAD1/FOS/PPARD/TGFB1/PDGFB/SREBF2	17
BP	GO:0002637	regulation of immunoglobulin production	24/4749	63/18670	0.01795	0.1169	0.09507	IL10/BCL6/TREX1/TNFSF4/TFRC/MZB1/GPI/TNF/TNFRSF4/FOXP3/IL4R/TP53BP1/PTPRC/HLA-E/SUPT6H/IL27RA/APLF/IL13/TRAF2/TNFSF13/IL4/MAD2L2/TRAF6/TGFB1	24
BP	GO:2001252	positive regulation of chromosome organization	57/4749	174/18670	0.01798	0.1169	0.09508	ESPL1/LIF/AURKB/IL1B/VEGFA/CDT1/NEK2/DLGAP5/BCL6/PHF19/SFPQ/PML/SIRT6/FOXP3/FEN1/SMARCB1/LMNA/NAP1L2/CCNB1/NUMA1/ARRB1/MORC2/KAT2A/UBE2N/RNF40/CCT5/TERF1/ZNF304/PINK1/EED/BRD4/TNKS2/MUC1/ACD/GNL3/ANAPC11/FMR1/GTF2H2/C6orf89/POT1/DDX11/DMRTC2/TADA2A/ATR/SPHK2/CTBP1/ATM/SMC5/TGFB1/MAPK1/PPHLN1/SETDB1/GATA3/ERCC1/FBXO4/CCT3/SIRT1	57
BP	GO:0030879	mammary gland development	48/4749	143/18670	0.01799	0.1169	0.09508	VDR/IQGAP3/VEGFA/ITGA2/CSF1R/OAS2/PTCH1/PML/SOCS2/CSF1/DHODH/HK2/FOXB1/BRCA2/BAX/CAPN1/GPX1/MSX1/SRC/ETV5/PAM/TGFB3/USF2/ARHGAP35/ARHGAP5/KDM5B/UPRT/SCRIB/ARG1/CEBPB/LRP5L/TPH1/DDR1/ZNF703/APRT/BTRC/ESR1/CSN2/STAT5A/LRP6/FASN/TNFSF11/LBH/TGFB1/MGMT/MAPK1/CCND1/GATA3	48
BP	GO:0014044	Schwann cell development	13/4749	29/18670	0.01814	0.1171	0.0953	NTRK2/CDK5/SKI/FA2H/NTRK3/MPP5/NDRG1/ADAM22/POU3F1/SIRT2/DICER1/MED12/ILK	13
BP	GO:0031063	regulation of histone deacetylation	13/4749	29/18670	0.01814	0.1171	0.0953	VEGFA/BCL6/ZNHIT1/SKI/FOXP3/PINK1/C6orf89/CAMK2D/KDM5A/SPHK2/CTBP1/TGFB1/USP17L2	13
BP	GO:0042226	interleukin-6 biosynthetic process	13/4749	29/18670	0.01814	0.1171	0.0953	IL1B/TIRAP/CLEC7A/TNF/CARD9/STAT3/CD74/TLR6/CEBPB/GHRL/TYROBP/TRAF6/PTAFR	13
BP	GO:0070723	response to cholesterol	13/4749	29/18670	0.01814	0.1171	0.0953	PTCH1/LRP8/GRAMD1C/PMVK/CCL3/CCR5/GRAMD1B/ABCA1/LRP6/OSBPL7/GRAMD1A/CYP7A1/TGFB1	13
BP	GO:0042278	purine nucleoside metabolic process	28/4749	76/18670	0.01816	0.1171	0.0953	ACPP/GAMT/TJP2/HPRT1/AK3/PNP/NME4/MRI1/NME3/ENPP4/MTRR/MTAP/AK4/MOCS1/APRT/IMPDH1/LRGUK/RAB23/CARD11/GNMT/GUK1/AMPD3/ENOPH1/NT5E/NFS1/NME9/NT5C2/NME2	28
BP	GO:0046785	microtubule polymerization	28/4749	76/18670	0.01816	0.1171	0.0953	FES/RAC1/HSPA1A/CENPJ/RANGRF/PSRC1/TPPP3/TPPP/FBXO5/NUMA1/CLIP3/PAK1/RPS3/TERF1/TUBGCP2/FGF13/STMN1/CLASP2/TUBG2/TUBB4A/CEP192/TUBG1/ARL2/SLAIN2/TUBGCP5/CDH5/CKAP5/TUBGCP3	28
BP	GO:0016572	histone phosphorylation	16/4749	38/18670	0.01821	0.1171	0.0953	TWIST1/AURKB/IL1B/CDK1/AURKA/CCNA2/CDK5/UBE2B/CCNB1/CDK2/PRKCA/DRD1/FMR1/CHEK1/PRKCB/ATM	16
BP	GO:0035329	hippo signaling	16/4749	38/18670	0.01821	0.1171	0.0953	YWHAE/NF2/TEAD3/TJP2/DCHS1/LIMD1/WWTR1/AMOT/STK3/WWC2/SOX11/YAP1/NEK8/DLG5/TEAD4/PJA2	16
BP	GO:0046825	regulation of protein export from nucleus	16/4749	38/18670	0.01821	0.1171	0.0953	IL1B/GTSE1/CAMK1/CDK5/YWHAE/RBM22/PTPN14/IWS1/SFN/TCF7L2/SUPT6H/PARK7/EMD/BAG3/UHMK1/BARD1	16
BP	GO:0006356	regulation of transcription by RNA polymerase I	14/4749	32/18670	0.01835	0.1171	0.0953	UBTF/MTOR/SMARCB1/ATF4/SMARCA4/NCL/DHX33/RASL11A/ERBB2/DDX11/EIF2AK3/IPPK/POU4F1/PHF8	14
BP	GO:0046685	response to arsenic-containing substance	14/4749	32/18670	0.01835	0.1171	0.0953	PPIF/CDKN1A/ATF3/CPOX/HMOX1/VCP/ATF4/GSTO1/ZC3H12A/TNFRSF11B/ZFAND2A/GCLC/NEFL/ZFAND1	14
BP	GO:0050779	RNA destabilization	14/4749	32/18670	0.01835	0.1171	0.0953	ZFP36/ZC3H12D/PLEKHN1/UPF1/ZFP36L2/MEX3D/RBM23/ZC3H12A/YTHDF3/METTL16/GIGYF2/TNFRSF1B/ZFP36L1/KHSRP	14
BP	GO:1901976	regulation of cell cycle checkpoint	14/4749	32/18670	0.01835	0.1171	0.0953	CDT1/CCNB1/NDC80/CRY1/RFWD3/FEM1B/WDR76/USP44/XRCC3/ETAA1/CHEK2/CUL4A/FBXO4/DUSP1	14
BP	GO:0009262	deoxyribonucleotide metabolic process	15/4749	35/18670	0.01836	0.1171	0.0953	DCTPP1/TYMS/RRM2B/CMPK2/DTYMK/NUDT16/NUDT1/AK5/RRM1/DCTD/SAMHD1/RRM2/GUK1/NEIL1/OGG1	15
BP	GO:0032735	positive regulation of interleukin-12 production	15/4749	35/18670	0.01836	0.1171	0.0953	MAPK11/TIRAP/TNFSF4/CLEC7A/LGALS9/HMGB1/IRF5/TLR4/HLA-G/TLR2/IDO1/RIPK2/TRAF6/PLCB1/IL23A	15
BP	GO:0042455	ribonucleoside biosynthetic process	15/4749	35/18670	0.01836	0.1171	0.0953	DHODH/HPRT1/NME4/UPRT/NME3/MTAP/APRT/IMPDH1/GUK1/NT5E/CMPK1/CTPS2/UCK2/NME9/NME2	15
BP	GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway	15/4749	35/18670	0.01836	0.1171	0.0953	HSPA1A/TLR4/UBB/UBE2N/MAP2K6/RPS27A/CYLD/UBA52/NOD2/IRAK1/TAB1/NFKBIA/BIRC3/RIPK2/TRAF6	15
BP	GO:2000785	regulation of autophagosome assembly	15/4749	35/18670	0.01836	0.1171	0.0953	MTMR3/PIKFYVE/PINK1/ULK1/KIAA1324/UBQLN2/NPRL3/LRSAM1/NUPR1/PIP4K2A/RALB/PIP4K2B/PHF23/RAB1B/NPRL2	15
BP	GO:0001776	leukocyte homeostasis	31/4749	86/18670	0.01867	0.119	0.09682	SKIL/SH2B2/CCNB2/LGALS9/HMGB1/IL2RA/BAX/PMAIP1/FOXP3/RIPK3/CCR2/MERTK/SIT1/RPS6/PDE4B/AXL/CD74/BAP1/FLT3/PPP2R3C/DNAJA3/CORO1A/LAT/BAK1/TNFRSF13B/TSC22D3/TGFB1/JAK3/MIR17HG/SLC40A1/P2RX7	31
BP	GO:1905037	autophagosome organization	34/4749	96/18670	0.01884	0.12	0.09762	TP53INP2/MTMR3/MAP1LC3A/ATG9A/ATP13A2/AMBRA1/PIKFYVE/SMURF1/PINK1/ULK1/GBA/TP53INP1/STX12/ATG2B/KIAA1324/BAG3/UBQLN2/NPRL3/RAB23/PIK3C3/ATG4B/NSFL1C/TMEM41B/LRSAM1/WDR45/NUPR1/PIP4K2A/RAB1A/RALB/PIP4K2B/PHF23/ATG7/RAB1B/NPRL2	34
BP	GO:0002716	negative regulation of natural killer cell mediated immunity	8/4749	15/18670	0.01916	0.1212	0.0986	CEACAM1/LGALS9/HLA-G/HAVCR2/HLA-E/MICA/CRK/CD96	8
BP	GO:0007512	adult heart development	8/4749	15/18670	0.01916	0.1212	0.0986	MYH10/MEF2D/MYH7/SCUBE1/MNAT1/BMP10/MYH6/TCAP	8
BP	GO:0032988	ribonucleoprotein complex disassembly	8/4749	15/18670	0.01916	0.1212	0.0986	DYRK3/KLC1/VCP/PELO/TFIP11/EIF2D/DENR/ZFAND1	8
BP	GO:0034349	glial cell apoptotic process	8/4749	15/18670	0.01916	0.1212	0.0986	CASP9/CDK5/TNFRSF21/CCL2/PRKCA/PRKCI/TRAF2/DLL1	8
BP	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	8/4749	15/18670	0.01916	0.1212	0.0986	TLR4/MAP2K6/CCL2/NAMPT/TLR2/NOD2/MAP2K4/STAT1	8
BP	GO:0071801	regulation of podosome assembly	8/4749	15/18670	0.01916	0.1212	0.0986	FSCN1/CSF2/HCK/TNF/GSN/SRC/ARHGEF5/ARHGEF2	8
BP	GO:1903543	positive regulation of exosomal secretion	8/4749	15/18670	0.01916	0.1212	0.0986	SDC4/SNF8/SDCBP/ATP13A2/STAM/SDC1/HGS/CHMP2A	8
BP	GO:0006109	regulation of carbohydrate metabolic process	66/4749	206/18670	0.01928	0.1217	0.09902	PHLDA2/SEC13/IGFBP4/TREX1/PFKFB3/PGAM1/CBFA2T3/SIRT6/PPP1CB/NUP98/ENTPD5/PMAIP1/MTOR/STAT3/SRC/HTR2A/CRY1/PFKFB4/KAT2A/NUP153/IGFBP3/FOXO1/RORC/DDIT4/PFKFB2/SLC45A3/NUP88/ADIPOR1/MAEA/PPP1R3E/PRKAG2/NTSR1/C1QTNF3/EPM2AIP1/POM121C/PRKCE/NUP205/RAE1/NUP50/GSK3A/PHKG2/GNMT/ADIPOQ/DGAT2/ACACB/P2RY1/INSR/NUPR1/NUP93/SLC35B4/NUP35/AAAS/TGFB1/CLK2/HAS2/COX11/PDGFB/NUP62/SESN2/PTAFR/P2RX7/SEH1L/NCOR1/BAD/PPP1R3B/SIRT1	66
BP	GO:0031032	actomyosin structure organization	64/4749	199/18670	0.01929	0.1217	0.09902	ANLN/SDC4/KIF23/CIT/SRF/RAC1/ZYX/RACGAP1/CDC42BPG/RTKN/NF2/FHOD1/MYH10/MTOR/BAG4/ACTG1/TMOD2/SRC/ARHGEF5/TNFAIP1/CFLAR/ARRB1/PTGER4/TGFB3/PAK1/PFN2/S1PR1/STMN1/CLASP2/CD47/LIMCH1/S100A10/MKKS/MYBPC3/ARAP1/LIMK1/EPB41L5/SH3PXD2B/NRAP/ECT2/WDR1/EPB41L2/FRMD5/KRT19/ALMS1/SFRP1/MYH9/KCTD13/MYOM1/OBSCN/EPB41/CNN2/FAM171A1/BMP10/TPM1/AKAP13/SORBS3/WASF2/MYH6/ALKBH4/CDC42/TCAP/WAS/MYBPC2	64
BP	GO:0051251	positive regulation of lymphocyte activation	102/4749	334/18670	0.01938	0.1222	0.09942	EGR3/EBI3/IL1B/CD86/IL18/CD276/IL21/CDKN1A/NLRP3/DUSP10/CD83/CD80/RAC1/PDCD1/PTPN6/BCL6/CBFB/SIRPA/TIRAP/TNFSF4/TFRC/CLEC7A/LGALS9/HMGB1/TNFRSF4/IL2RA/TLR4/BTN2A2/FOXP3/CTLA4/IL4R/DOCK8/TOX/CCR2/SRC/HLA-G/TP53BP1/LILRB4/BTK/HAVCR2/AXL/CD74/PAK1/CD1D/GRAP2/RPS3/EFNB1/HLX/LGALS1/PPP2R3C/CCL2/PNP/PAK3/DNAJA3/HLA-DPA1/PTPRC/CYLD/CORO1A/HLA-E/CD47/AIF1/AP3D1/SART1/NOD2/LILRB2/IL12RB1/THY1/CD46/IL7R/HLA-DMB/TNFSF9/PDCD1LG2/IL7/CD3E/IL13/CCDC88B/CARD11/LAMP1/TNFSF13/IL4/RIPK2/TYROBP/CD6/MAD2L2/HLA-DPB1/TRAF6/VNN1/ATP11C/TNFSF11/SLC39A10/TGFB1/CDC42/JAK3/RARA/HHLA2/KLRK1/ZAP70/GATA3/BAD/FYN/PAK2/IL23A	102
BP	GO:0008652	cellular amino acid biosynthetic process	30/4749	83/18670	0.01966	0.1237	0.1006	BCAT1/SERINC3/GAMT/RIMKLB/GGT1/GLS2/ABAT/GPT/ASNS/CTH/MRI1/MTHFD1/BHMT/ATP2B4/NAGS/PARK7/SEPHS1/NAT8L/MTRR/MTAP/DPYD/PSPH/GLUD1/ENOPH1/AASDHPPT/MTR/GPT2/PLOD3/ASNSD1/BHMT2	30
BP	GO:2000106	regulation of leukocyte apoptotic process	30/4749	83/18670	0.01966	0.1237	0.1006	AURKB/IRF7/NR4A3/IL10/PDCD1/BCL6/LGALS3/PRELID1/LGALS9/BAX/DOCK8/RIPK3/MERTK/BTK/AXL/CD74/CCR5/CDKN2A/NOD2/IL7R/IDO1/GIMAP8/RAPGEF2/TSC22D3/BIRC7/SLC39A10/JAK3/MIR17HG/P2RX7/SIRT1	30
BP	GO:0046677	response to antibiotic	100/4749	327/18670	0.01968	0.1237	0.1006	EGR1/PPIF/TXNIP/CDK1/NR4A3/ICAM1/CASP9/FOSL1/KLF2/IL10/KLF4/SPI1/LDHA/SIRPA/TYMS/EIF4EBP1/SETD7/HSPA5/GSN/CRIP1/CYBB/RPL10A/MAP1LC3A/GPX1/PLEKHA1/HYAL3/STAT3/VKORC1/RIPK3/FXN/SRC/HMOX1/PRDX3/CCR4/ABAT/GGH/CLU/NTRK3/AXL/ADCY6/RPS3/SLC2A4/HBA2/NQO1/FOXO1/SDC1/KCNMB1/CBX8/MAP3K5/RPL23/PINK1/RGS19/KDM5B/EZH2/OXCT1/TIMELESS/BAK1/TP53INP1/ARG1/CNR1/RSRC1/PARK7/STK25/JUN/PPP5C/UBE3A/CRK/PRKCE/ECT2/ADCY3/RPS4X/BCL2L1/ZC3H12A/TBXA2R/IL13/DDX11/BGLAP/S100A8/ADIPOQ/HBB/STAT1/HPGD/NEFL/CCL7/OGG1/ID1/NET1/MGMT/RARA/CCND1/ADAM9/SETDB1/PDGFB/TUFM/GATA3/BAD/FYN/JAK1/SIRT1/DUSP1	100
BP	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	33/4749	93/18670	0.01987	0.1248	0.1015	AURKB/TICRR/CDK1/AURKA/CLSPN/CDC6/PSMD8/PSMD1/PSMD2/ORC1/TOPBP1/PSMF1/PSMD9/PSMA5/TAOK3/PSMB7/GPR132/PSMD5/MIIP/ZNF830/PSME2/PSMB5/NAE1/PSMB4/PSMA3/ATM/PSMD10/PSMB1/PSMD7/PSMB3/SYF2/PSMC5/PSMD11	33
BP	GO:0051607	defense response to virus	75/4749	238/18670	0.0199	0.1248	0.1016	IL1B/IRF7/NLRP3/IFIT1/TSPAN32/BNIP3L/ISG15/TLR8/TREX1/OAS2/APOBEC3H/UNC93B1/PML/SERINC3/MX1/PQBP1/IRF5/IL2RA/CXCL10/TRIM25/PMAIP1/IFIT5/MMP12/CARD9/APOBEC3B/RSAD2/IFITM2/IFI6/DTX3L/SEC14L1/CD207/BST2/IFIT3/OASL/TRIM22/NPLOC4/ISG20/POLR3H/PTPRC/ABCE1/DDIT4/CXCL9/TRIM44/MICA/IL12RB1/IFITM3/AICDA/IFITM1/RNF216/UNC13D/DDX17/RNASE6/IRF3/ZC3H12A/SAMHD1/BIRC3/OAS1/CNOT7/IFI16/ILF3/ZC3HAV1/DEFA1B/C1QBP/IFIT2/CRCP/TSPAN6/STAT1/HTRA1/ANKRD17/ATG7/ZCCHC3/USP17L2/TRIM15/IL23A/TRIM5	75
BP	GO:0002720	positive regulation of cytokine production involved in immune response	21/4749	54/18670	0.02026	0.1269	0.1032	IL1B/IL18/NR4A3/NLRP3/IL1R1/HK1/TNFSF4/SEMA7A/TLR4/RSAD2/FFAR2/HLA-G/CD74/FFAR3/HLA-E/NOD2/IL18R1/TRAF2/TRAF6/FZD5/GATA3	21
BP	GO:1900047	negative regulation of hemostasis	21/4749	54/18670	0.02026	0.1269	0.1032	PDGFA/PLAUR/ANXA2P2/CEACAM1/CD9/PROS1/TMPRSS6/PROC/PLAU/SERPINE1/ADTRP/ANXA2/PLAT/ABAT/ANXA5/VTN/KLKB1/SERPING1/CD34/PDGFB/TFPI	21
BP	GO:0007266	Rho protein signal transduction	65/4749	203/18670	0.02034	0.1271	0.1034	CDC42EP4/TIAM2/PLEKHG2/ARHGEF39/ITGA3/KANK2/RAC1/ARHGEF40/BCL6/RTKN/ARHGEF18/FGD2/CDC42SE1/MCF2L2/CDC42EP1/ARHGEF12/ARHGEF5/TNFAIP1/RHOG/TIAM1/ARHGEF2/F2RL2/ARRB1/ARHGAP35/RASGRF2/ARHGAP5/GPR35/SYNJ2BP/PREX1/PLEKHG1/EPS8L2/VAV2/STMN1/ARHGAP4/CFL1/PLEKHG7/ABCA1/FLOT1/P2RY10/CCDC125/LIMK1/RAC2/ECT2/MYO9B/RHOF/RHOV/RHOU/KCTD13/F2R/OBSCN/RHOT2/CDC42SE2/ARHGDIA/AKAP13/BCR/ARHGAP1/MCF2L/C15orf62/CDC42/WAS/NET1/RTN4R/SPATA13/ARHGEF26/RAC3	65
BP	GO:0071214	cellular response to abiotic stimulus	101/4749	331/18670	0.02036	0.1271	0.1034	EGR1/AURKB/IL1B/PBK/RELB/CDKN1A/ITGA2/CASP9/RAC1/SERPINB6/TLR8/TREX1/CDC25A/ASCL1/DDB2/HSPA5/CRIP1/TNFRSF8/TLR4/BAX/GADD45A/SLC25A23/RAD51/TMEM150C/HYAL3/RAD51AP1/TSPO/ARHGEF2/RPL26/TP53BP1/BMF/MAP3K2/PTGER4/MICU1/CRY1/KCNJ2/PKD2/ATF4/XRCC6/SLC2A4/N4BP1/GUCA1C/NMT1/AQP2/FAS/TNFRSF10B/NAMPT/GPR68/FIGNL1/HVCN1/BAK1/TANK/TP53INP1/BDKRB2/CASP8AP2/INSRR/CHP1/CNGA1/GPR52/ELK1/SLC38A2/FMR1/CHEK1/PIEZO1/ECT2/RBL2/BCL2L1/CYBA/YAP1/BAG3/MAP2K4/IL13/IFI16/KCNK18/SFRP1/RAB11FIP5/ZFP36L1/GCLC/CNN2/ATR/CHEK2/SLC12A6/LRRC8D/FNTB/GTF2H5/CAMKMT/XPA/ATM/NUCKS1/WRN/TGFB1/NET1/MGMT/GATA3/PTAFR/PDE6B/ERCC1/FBXO4/BAD/RAD9A/SIRT1	101
BP	GO:0104004	cellular response to environmental stimulus	101/4749	331/18670	0.02036	0.1271	0.1034	EGR1/AURKB/IL1B/PBK/RELB/CDKN1A/ITGA2/CASP9/RAC1/SERPINB6/TLR8/TREX1/CDC25A/ASCL1/DDB2/HSPA5/CRIP1/TNFRSF8/TLR4/BAX/GADD45A/SLC25A23/RAD51/TMEM150C/HYAL3/RAD51AP1/TSPO/ARHGEF2/RPL26/TP53BP1/BMF/MAP3K2/PTGER4/MICU1/CRY1/KCNJ2/PKD2/ATF4/XRCC6/SLC2A4/N4BP1/GUCA1C/NMT1/AQP2/FAS/TNFRSF10B/NAMPT/GPR68/FIGNL1/HVCN1/BAK1/TANK/TP53INP1/BDKRB2/CASP8AP2/INSRR/CHP1/CNGA1/GPR52/ELK1/SLC38A2/FMR1/CHEK1/PIEZO1/ECT2/RBL2/BCL2L1/CYBA/YAP1/BAG3/MAP2K4/IL13/IFI16/KCNK18/SFRP1/RAB11FIP5/ZFP36L1/GCLC/CNN2/ATR/CHEK2/SLC12A6/LRRC8D/FNTB/GTF2H5/CAMKMT/XPA/ATM/NUCKS1/WRN/TGFB1/NET1/MGMT/GATA3/PTAFR/PDE6B/ERCC1/FBXO4/BAD/RAD9A/SIRT1	101
BP	GO:0006352	DNA-templated transcription, initiation	78/4749	249/18670	0.02064	0.1287	0.1047	VDR/NR4A1/TWIST1/NOTCH1/CDK1/CDKN1A/NR4A3/PPARG/NR3C2/FOSL1/GTF3C4/E2F2/SRF/CBFB/THRA/MAML1/HMGB1/BAX/TEAD3/UBTF/ESRRA/MED20/WNT10B/SMARCB1/NR3C1/MAML2/CCNB1/SNAPC5/MED4/WWTR1/RBPJ/RUNX2/BRF2/RORC/POLR3H/CDK7/TAF1L/SMARCA4/TAF9B/MED24/TAF6L/TAF10/RXRA/NRBP1/POLR2I/JUN/ERCC2/TAF11/GTF2H2/POLR2C/YAP1/GTF2H1/TAF1A/ZNRD1/NAT14/TAF7/ESR1/TAF6/BDP1/MNAT1/TAF1D/BAZ2A/POLR2J/CRCP/MED12/GTF2H5/TFB2M/PPARD/TEAD4/POLR2A/CCNC/ZNF451/NR2C1/RARA/CCND1/PSMC5/POLR1B/GTF2I	78
BP	GO:0090175	regulation of establishment of planar polarity	38/4749	110/18670	0.02065	0.1287	0.1047	SAPCD2/RAC1/VANGL1/NKD1/TIAM1/CTHRC1/PSMD8/DVL3/PSMD1/PSMD2/FZD6/PTK7/PSMF1/SMURF1/DVL1/PSMD9/AP2S1/PSMA5/WNT7A/PSMB7/PSMD5/PSME2/SFRP1/RSPO3/PSMB5/MLLT3/PSMB4/PSMA3/MED12/PARD6A/FZD5/PSMD10/CDC42/PSMB1/PSMD7/PSMB3/PSMC5/PSMD11	38
BP	GO:1900046	regulation of hemostasis	29/4749	80/18670	0.02069	0.1288	0.1048	PDGFA/PLAUR/HPSE/ANXA2P2/CEACAM1/CD9/PROS1/TMPRSS6/TLR4/PROC/PLAU/SERPINE1/ADTRP/ANXA2/VKORC1/PLAT/ABAT/PRKCA/ANXA5/VTN/ENPP4/KLKB1/TBXA2R/SERPING1/F3/CD34/F2R/PDGFB/TFPI	29
BP	GO:0042274	ribosomal small subunit biogenesis	25/4749	67/18670	0.02096	0.13	0.1057	RPS8/RPS27/RPL38/RPS10/RPS5/RPS6/RPS15/MRPS11/BYSL/RPS19/FAM207A/RIOK1/RPS16/NOP14/UTP20/EMG1/UTP23/RPSA/BTRC/ABT1/RPS28/NOM1/RCL1/UTP3/NGDN	25
BP	GO:0046365	monosaccharide catabolic process	25/4749	67/18670	0.02096	0.13	0.1057	TPI1/GAPDH/HK1/GLB1/ENO1/PGAM1/PFKP/GPI/HK2/PGM2L1/PKM/ALDOC/GALK2/GALK1/PFKFB2/ENO3/GALM/ALDOA/FUT6/RPE/GALT/PFKL/ALDOB/AKR1A1/BAD	25
BP	GO:0042475	odontogenesis of dentin-containing tooth	32/4749	90/18670	0.02096	0.13	0.1057	JAG2/PERP/CSF3R/TP63/NF2/CSF1/BAX/SERPINE1/MSX1/FAM20C/RUNX2/FOXO1/LRP4/CNNM4/ITGA6/AMTN/ROGDI/ACVR2B/CA2/BSG/CTNNA1/ADM/TNFRSF11B/LRP6/KLK5/TRAF6/FGF8/EDAR/HTRA1/LAMA5/AMELX/ANKRD11	32
BP	GO:0071674	mononuclear cell migration	32/4749	90/18670	0.02096	0.13	0.1057	CCL20/CCL3L3/SIRPA/CCL22/CCR1/LGALS3/HMGB1/TNF/CSF1/CXCL10/SERPINE1/CCR2/CCL3/CCL2/CCL17/RPS19/CD47/AIF1/CCL18/FLT1/FPR2/C3AR1/RARRES2/CCL23/TNFSF11/CCL7/PLCB1/TGFB1/CCL15/PDGFB/CCL27/DUSP1	32
BP	GO:0006213	pyrimidine nucleoside metabolic process	20/4749	51/18670	0.02103	0.1302	0.1059	TYMP/APOBEC3H/DHODH/TK1/APOBEC3B/ERH/DTYMK/AK3/NME4/UPRT/AICDA/NME3/DPYD/ENTPD4/NT5E/CMPK1/CTPS2/UCK2/NME9/NME2	20
BP	GO:0060070	canonical Wnt signaling pathway	102/4749	335/18670	0.02104	0.1302	0.1059	EGR1/ZBED2/NOTCH1/ASPM/WNK1/SULF2/GSKIP/KLF4/IGFBP4/TLE4/LRRK1/UBE2B/TLE2/WNT10B/GID8/SRC/NKD1/CTHRC1/LIMD1/PSMD8/VCP/DVL3/SFRP4/TMEM170B/PSMD1/PSMD2/FZD6/PTK7/WWTR1/FGF9/RBPJ/PSMF1/CDK14/PFDN5/FOXO1/SDC1/LRP4/TCF7L2/CYLD/STK3/TRPM4/TLE3/DVL1/TNKS2/PRDM15/PSMD9/PSMA5/DDIT3/WNT7A/FAM53B/FRAT1/FZD8/RAPGEF1/EMD/PSMB7/INVS/RECK/PSMD5/LRP5L/ARNTL/YAP1/NRARP/ZNF703/SIAH2/TMEM198/GSK3A/PSME2/BTRC/SFRP1/RSPO3/PSMB5/DLX5/MLLT3/BICC1/FZD9/MAD2L2/LRP6/PYGO1/PSMB4/GNAQ/FGF8/PSMA3/CCNY/ZBED3/APC/MED12/AXIN2/FZD5/PORCN/PSMD10/MYH6/TMEM64/SEMA5A/PSMB1/PSMD7/CSNK1G2/PSMB3/PSMC5/GATA3/IGFBP6/ILK/PSMD11	102
BP	GO:0007272	ensheathment of neurons	45/4749	134/18670	0.02125	0.1304	0.1061	EGR2/KIF14/NTRK2/TYMP/GPC1/CD9/SKI/TNFRSF21/MTOR/ABCD1/ITGAX/MYO5A/FA2H/ABCD2/NAB2/CLU/AMIGO1/NTRK3/PIKFYVE/SBF2/MPP5/NDRG1/MARVELD1/TLR2/ZNF24/NAB1/ERCC2/ERBB2/ADAM22/PMP22/POU3F1/B4GALT5/SIRT2/CMTM8/EIF2AK3/TNFRSF1B/DICER1/GALC/HEXB/ATRN/PPARD/NKX6-2/TGFB1/RARA/ILK	45
BP	GO:0008366	axon ensheathment	45/4749	134/18670	0.02125	0.1304	0.1061	EGR2/KIF14/NTRK2/TYMP/GPC1/CD9/SKI/TNFRSF21/MTOR/ABCD1/ITGAX/MYO5A/FA2H/ABCD2/NAB2/CLU/AMIGO1/NTRK3/PIKFYVE/SBF2/MPP5/NDRG1/MARVELD1/TLR2/ZNF24/NAB1/ERCC2/ERBB2/ADAM22/PMP22/POU3F1/B4GALT5/SIRT2/CMTM8/EIF2AK3/TNFRSF1B/DICER1/GALC/HEXB/ATRN/PPARD/NKX6-2/TGFB1/RARA/ILK	45
BP	GO:0045732	positive regulation of protein catabolic process	68/4749	214/18670	0.02134	0.1304	0.1061	IL1B/RNF144A/FURIN/DTL/AURKA/TRIB1/SGSM3/SNX9/CBFA2T3/TNF/HSPA1A/PLK2/ECSCR/PLK1/DET1/LDLR/SNF8/SMAD7/SORL1/STX5/NKD1/VCP/CLU/MAGEF1/HERPUD1/MYLIP/FOXO1/RNF40/SGTA/SMURF1/OAZ3/PIAS1/EZR/BCAP31/DVL1/LRP1/GBA/SUMO1/RNF19B/RHBDD3/FMR1/TNFSF12/OAZ2/RAD23A/ASB11/SNX33/EDEM2/USP5/GSK3A/UBQLN2/BAG2/SIRT2/ZFAND2A/TNFRSF1B/ATG4B/RNF139/GCLC/NUPR1/OSBPL7/APC/OAZ1/PSMD10/ATG7/NDUFA13/DNAJB2/ADAM9/BARD1/TRIB3	68
BP	GO:1903050	regulation of proteolysis involved in cellular protein catabolic process	68/4749	214/18670	0.02134	0.1304	0.1061	PBK/RNF144A/AURKA/TRIB1/PML/CBFA2T3/HSPA1A/PLK2/ECSCR/PLK1/DET1/GPX1/WNT10B/SMAD7/RYBP/RPL5/VCP/SDCBP/CLU/USP19/UBB/MAGEF1/HERPUD1/PSMF1/N4BP1/UBXN1/RNF40/PDCL3/SGTA/SMURF1/RPL23/PINK1/UBE2G2/PIAS1/BCAP31/RAD23B/DVL1/GBA/SUMO1/RNF19B/PARK7/FMR1/UBE3A/RAD23A/SCO1/EDEM2/USP5/UCHL5/GSK3A/PSME2/BRSK2/BTRC/UBQLN2/BAG2/SIRT2/ZFAND2A/RNF139/GCLC/MAP1A/NUPR1/OSBPL7/RPL11/PSMD10/GLMN/TMF1/DNAJB2/UBAC2/TRIB3	68
BP	GO:1900371	regulation of purine nucleotide biosynthetic process	40/4749	117/18670	0.02136	0.1304	0.1061	PDPR/SEC13/TREX1/PFKFB3/ENO1/PGAM1/CBFA2T3/SIRT6/NUP98/ENTPD5/DNAJC30/STAT3/VCP/HTR2A/PFKFB4/NUP153/GUCA1C/PINK1/DDIT4/PFKFB2/NUP88/PRKAG2/POM121C/AK4/NUP205/RAE1/NUP50/IL4/INSR/NUPR1/SPHK2/NUP93/NUP35/AAAS/TAZ/GSTZ1/NUP62/P2RX7/SEH1L/NCOR1	40
BP	GO:0008064	regulation of actin polymerization or depolymerization	58/4749	179/18670	0.02143	0.1304	0.1061	CDC42EP4/PLEKHG2/ICAM1/CIT/HCK/CYFIP1/SNX9/CAPZB/GSN/CTTN/MTOR/MYADM/BAG4/CDC42EP1/SWAP70/TMOD2/TENM1/CAPG/CORO1B/PDXP/WHAMMP3/ADD3/PFN2/HIP1R/ARHGAP35/ARPC1B/PAK3/PREX1/PICK1/TMSB4Y/SPTBN1/CORO1A/VASP/TRIOBP/TWF2/CFL1/COTL1/SPTAN1/ARPC5/MKKS/CAPZA1/PRKCE/ACTR3B/KANK3/WDR1/TMSB15A/VILL/FER/ARF6/ARHGAP18/WHAMM/AP1AR/C15orf62/SEMA5A/WAS/FMN1/ADD2/RAC3	58
BP	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	6/4749	10/18670	0.02145	0.1304	0.1061	ICAM1/LGALS3/LGALS9/HAVCR2/APBB1IP/HLA-DMB	6
BP	GO:0032875	regulation of DNA endoreduplication	6/4749	10/18670	0.02145	0.1304	0.1061	E2F7/E2F8/SMC3/MSH6/FBXO5/SMC1A	6
BP	GO:0034350	regulation of glial cell apoptotic process	6/4749	10/18670	0.02145	0.1304	0.1061	CDK5/CCL2/PRKCA/PRKCI/TRAF2/DLL1	6
BP	GO:0045625	regulation of T-helper 1 cell differentiation	6/4749	10/18670	0.02145	0.1304	0.1061	CD80/TNFSF4/IL4R/HLX/RIPK2/JAK3	6
BP	GO:0051255	spindle midzone assembly	6/4749	10/18670	0.02145	0.1304	0.1061	AURKB/KIF4A/KIF23/RACGAP1/KIF4B/CCDC69	6
BP	GO:0051409	response to nitrosative stress	6/4749	10/18670	0.02145	0.1304	0.1061	DUSP6/DNAJA1/DDIT3/PARK7/GCLC/ATM	6
BP	GO:0060068	vagina development	6/4749	10/18670	0.02145	0.1304	0.1061	TYRO3/BAX/MERTK/AXL/BAK1/ESR1	6
BP	GO:1901725	regulation of histone deacetylase activity	6/4749	10/18670	0.02145	0.1304	0.1061	VEGFA/PINK1/C6orf89/CAMK2D/KDM5A/SPHK2	6
BP	GO:1901838	positive regulation of transcription of nucleolar large rRNA by RNA polymerase I	6/4749	10/18670	0.02145	0.1304	0.1061	MTOR/SMARCB1/SMARCA4/NCL/DDX11/IPPK	6
BP	GO:1903332	regulation of protein folding	6/4749	10/18670	0.02145	0.1304	0.1061	GRN/PDCL/HSPA5/PDCD5/SGTA/DNAJB2	6
BP	GO:1904779	regulation of protein localization to centrosome	6/4749	10/18670	0.02145	0.1304	0.1061	MARK4/NSFL1C/CEP72/APC/PARD6A/NUP62	6
BP	GO:2000644	regulation of receptor catabolic process	6/4749	10/18670	0.02145	0.1304	0.1061	FURIN/ANXA2P2/PTPN1/ANXA2/DTX3L/MYLIP	6
BP	GO:0050657	nucleic acid transport	62/4749	193/18670	0.0215	0.1304	0.1061	MVP/SEC13/U2AF1/SFPQ/ZFP36/NUP98/SMG5/POLDIP3/TST/MRPL18/IWS1/RNPS1/RPS15/HNRNPA3/ENY2/SRSF4/ZC3H3/NUP153/UPF1/MAGOHB/ABCE1/ALKBH5/RFTN1/FLOT1/SUPT6H/NUP88/THOC3/FMR1/U2AF1L4/PARP11/POM121C/NUP205/RAE1/SIDT2/NUP50/DHX38/SDAD1/UPF3A/MAGOH/LRPPRC/CPSF1/SMG6/ZFP36L1/GLE1/CETN2/SNUPN/CPSF6/NUP93/DDX19A/CDC40/RBM27/CETN3/NUP35/AAAS/NCBP2/NUP62/SEH1L/KHSRP/YTHDC1/CKAP5/TERF2/NXF3	62
BP	GO:0050658	RNA transport	62/4749	193/18670	0.0215	0.1304	0.1061	MVP/SEC13/U2AF1/SFPQ/ZFP36/NUP98/SMG5/POLDIP3/TST/MRPL18/IWS1/RNPS1/RPS15/HNRNPA3/ENY2/SRSF4/ZC3H3/NUP153/UPF1/MAGOHB/ABCE1/ALKBH5/RFTN1/FLOT1/SUPT6H/NUP88/THOC3/FMR1/U2AF1L4/PARP11/POM121C/NUP205/RAE1/SIDT2/NUP50/DHX38/SDAD1/UPF3A/MAGOH/LRPPRC/CPSF1/SMG6/ZFP36L1/GLE1/CETN2/SNUPN/CPSF6/NUP93/DDX19A/CDC40/RBM27/CETN3/NUP35/AAAS/NCBP2/NUP62/SEH1L/KHSRP/YTHDC1/CKAP5/TERF2/NXF3	62
BP	GO:1901654	response to ketone	62/4749	193/18670	0.0215	0.1304	0.1061	TXNIP/CDKN1A/PPARG/ICAM1/CASP9/FOSL1/KLF2/KLF4/TNFSF4/GLB1/SPP1/FOSB/TYMS/EIF4EBP1/CYBB/NASP/NR3C1/TSPO/SRC/CFLAR/NDOR1/PTGER4/NTRK3/TGFB3/ADCY6/DCPS/FOXO1/DDIT4/KLF9/TLR2/GBA/ARG1/PARK7/ELK1/ABCB4/UBE3A/PRKCE/PTGER2/ADCY3/BCL2L1/CYBA/PSPH/YAP1/ADAM15/TBXA2R/BGLAP/SFRP1/HSD3B2/CDC5L/MAP4K1/AANAT/SPHK2/NEFL/FOS/CATSPER2/TGFB1/CCND1/CLDN4/PTAFR/BAD/SIRT1/DUSP1	62
BP	GO:0001911	negative regulation of leukocyte mediated cytotoxicity	9/4749	18/18670	0.02158	0.1305	0.1062	CEACAM1/LGALS9/HLA-G/HAVCR2/PTPRC/HLA-E/MICA/CRK/IL7R	9
BP	GO:0009200	deoxyribonucleoside triphosphate metabolic process	9/4749	18/18670	0.02158	0.1305	0.1062	DCTPP1/TYMS/RRM2B/CMPK2/DTYMK/NUDT16/NUDT1/SAMHD1/GUK1	9
BP	GO:0031468	nuclear envelope reassembly	9/4749	18/18670	0.02158	0.1305	0.1062	PPP2R1A/REEP3/LMNA/REEP4/PPP2CA/BANF1/EMD/NSFL1C/CHMP2A	9
BP	GO:0050709	negative regulation of protein secretion	47/4749	141/18670	0.02165	0.1308	0.1064	IL1B/NLRP3/IL10/TLR8/PIM3/RAB11FIP1/PML/TNF/TNFRSF4/CD200/BTN2A2/TNFRSF21/FOXP3/ADTRP/IL1R2/RSAD2/FRMD4A/SYT4/PTGER4/ENY2/ENHO/EZR/ANXA5/PSMD9/IL27RA/C1QTNF3/TLR6/RAB11FIP3/ACVR1C/ANXA4/DEFB114/SYT11/SRGN/ZC3H12A/RABGEF1/LILRA5/SFRP1/GHRL/CD34/RAB11FIP5/F2R/HDAC9/CARD8/PFKL/NPFF/NDUFAF2/LRRC32	47
BP	GO:0048678	response to axon injury	28/4749	77/18670	0.02177	0.131	0.1066	CDK1/PTPRF/NTRK1/KLF4/GRN/CNTF/SPP1/BAX/RGMA/TSPO/NTRK3/LGALS1/DHFR/AIF1/SCARF1/LRP1/ARG1/JUN/CTNNA1/ARF4/PTPRS/TYROBP/MTR/MAX/NEFL/RTN4R/KCNK2/GIPR	28
BP	GO:1901224	positive regulation of NIK/NF-kappaB signaling	28/4749	77/18670	0.02177	0.131	0.1066	IL1B/IL18/NR3C2/TIRAP/LGALS9/HMGB1/TNF/TLR4/PDCD4/TRIP6/HAVCR2/LIMS1/RPS3/TNFRSF10B/ACTN4/TLR2/TRIM44/NOD2/TRAF4/IRAK1/IL18R1/TLR6/TRAF2/TRAF6/EDAR/PTP4A3/ILK/IL23A	28
BP	GO:0001774	microglial cell activation	19/4749	48/18670	0.02178	0.131	0.1066	TTBK1/TLR8/GRN/TNF/LDLR/CCL3/CLU/NAMPT/PTPRC/AIF1/TLR2/TLR6/FPR2/JUN/IL13/IFNGR1/TYROBP/C1QA/ATM	19
BP	GO:0002269	leukocyte activation involved in inflammatory response	19/4749	48/18670	0.02178	0.131	0.1066	TTBK1/TLR8/GRN/TNF/LDLR/CCL3/CLU/NAMPT/PTPRC/AIF1/TLR2/TLR6/FPR2/JUN/IL13/IFNGR1/TYROBP/C1QA/ATM	19
BP	GO:0030865	cortical cytoskeleton organization	19/4749	48/18670	0.02178	0.131	0.1066	ANLN/KIF23/CIT/RACGAP1/CDK5/RTKN/TNF/WIPF2/PLS1/RAB13/FMNL1/PPP2R3C/EZR/ECT2/WDR1/EPB41L2/EPB41/ARF6/WAS	19
BP	GO:0050900	leukocyte migration	147/4749	499/18670	0.02191	0.1316	0.1071	CXCL13/IL1B/VEGFA/SDC4/SLC16A3/HSD3B7/ITGA2/WNK1/ICAM1/ITGA3/IL10/IL1R1/CCL20/CCL3L3/HCK/RAC1/PTPN6/SLC7A5/IL17A/TNFRSF18/IL1RN/SLC16A1/CH25H/OLR1/CSF3R/SIRPA/CCL22/TIRAP/CCR1/DAPK2/GPC1/CYP7B1/LGALS3/CEACAM1/LGALS9/CD9/HMGB1/TNF/CSF1/PROS1/CD200/CXCL10/SERPINE1/ADTRP/ITGAX/FFAR2/DOCK8/SWAP70/CCR6/RIPK3/CCR2/SRC/HMOX1/GCSAM/ARHGEF5/MERTK/SLC12A2/PDE4D/CCL3/PTGER4/PDE4B/SDC2/CD74/CD177/SLC3A2/GYPC/CCR5/FCAMR/S1PR1/CCL2/CEACAM5/PREX1/CCL17/ATP1B1/SDC1/TNFRSF10B/RPS19/CORO1A/TRPM4/ITGA1/CD47/AIF1/CCL18/L1CAM/ITGA6/CXCL9/CXCL16/SBDS/CD58/IL27RA/THY1/FLT1/CXCL2/CXCL3/FPR2/ATP1B3/GBF1/C3AR1/CD48/IL17RC/CD44/CRK/RAC2/WDR1/CD99L2/RABGEF1/BSG/PADI2/RARRES2/S100A8/CD34/MYH9/CKLF/FER/UMOD/DOK2/IL36A/ITGA2B/DEFA1B/TREM1/C1QBP/CCL23/BCR/GCSAML/TNFSF11/CCL7/PPBP/THBS4/DDT/PLCB1/TGFB1/CCL15/KLRK1/CXCR5/PDGFB/ZAP70/GATA3/PTAFR/ADD2/SHC1/CCL27/CX3CR1/VEGFC/FYN/IL37/IL23A/DUSP1	147
BP	GO:0048247	lymphocyte chemotaxis	24/4749	64/18670	0.02195	0.1318	0.1072	CXCL13/HSD3B7/WNK1/CCL20/CCL3L3/CH25H/CCL22/CYP7B1/CXCL10/CCR2/SLC12A2/CCL3/CCL2/CCL17/CCL18/CXCL16/PADI2/CKLF/DEFA1B/CCL23/CCL7/CCL15/KLRK1/CCL27	24
BP	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling	42/4749	124/18670	0.02197	0.1318	0.1072	TWIST1/IL18/PTPN13/NTRK2/CEP55/NTRK1/KLF4/PDGFA/PTPN6/IER3/CEACAM1/STAMBP/PLXNB1/TNF/BTN2A2/ENTPD5/SRC/NTRK3/IGF1R/PIK3R5/FLT3/PIP5K1B/OSM/FLT1/PPP1R16B/UBE3A/NLRC3/FLT4/F2R/SEMA4D/INSR/PIP4K2A/NCF1/NTF3/PIP4K2B/PPARD/PIP5K1A/HCST/MAPK1/PDGFB/FYN/SIRT1	42
BP	GO:2001022	positive regulation of response to DNA damage stimulus	34/4749	97/18670	0.02209	0.1324	0.1077	SKIL/FOXM1/SPRED2/ZNF385A/HMGB1/PMAIP1/MSX1/NUDT16/DTX3L/RPL26/UBE2N/RPS3/EYA2/CBX8/EID3/ERCC8/TIMELESS/RNF8/BRCC3/FMR1/XRCC1/WRAP53/DDX11/PIAS4/MAD2L2/ATR/FAM168A/ATM/WAS/MGMT/HDAC10/RNF168/RAD9A/SIRT1	34
BP	GO:0000302	response to reactive oxygen species	73/4749	232/18670	0.02211	0.1324	0.1077	PPIF/TXNIP/CDK1/NR4A3/FOSL1/KLF2/IL10/KLF4/CCNA2/TREX1/LDHA/SIRPA/MPV17/MMP9/TNF/MAP1LC3A/GPX1/PLEKHA1/RIPK3/FXN/SRC/HMOX1/PRDX3/PPARGC1B/CFLAR/BTK/CDK2/AXL/PKD2/PRDX5/RPS3/HBA2/NQO1/FOXO1/DHFR/SDC1/CBX8/MAP3K5/PINK1/ROMO1/EZH2/FANCC/BAK1/ARG1/PARK7/STK25/JUN/PPP5C/UBE3A/CRK/ECT2/MPO/TRAF2/FER/HBB/ERCC6L2/MTR/TPM1/STAT1/CCS/ADPRHL2/NCF1/FOS/TXNRD2/NET1/MAPK1/ADAM9/SESN2/PRDX1/BAD/FYN/SIRT1/DUSP1	73
BP	GO:0033157	regulation of intracellular protein transport	71/4749	225/18670	0.02227	0.1332	0.1084	IL1B/GTSE1/KIF20B/BNIP3L/CAMK1/CDK5/YWHAE/RBM22/PTPN1/BAG4/PTPN14/SORL1/USP36/SAE1/TENM1/GRIPAP1/SEC16A/B3GAT3/IWS1/SFN/ATP13A2/PAK1/BAP1/PDCD5/PARL/NUCB1/HPS4/TCF7L2/PINK1/UBE2G2/BCAP31/SUPT6H/INSIG1/TMEM30A/NOLC1/CHP1/PARK7/EMD/EFCAB7/ERBB2/CABP1/OAZ2/RAC2/ECT2/EDEM2/ZC3H12A/BAG3/GSK3A/BRSK2/RHOU/UBL5/RAB23/ADIPOQ/PRNP/UHMK1/HSPA1L/OAZ1/FZD5/STOM/ZFAND1/RUFY3/TGFB1/BCAS3/MAPK1/NUP62/UBAC2/GDI1/USP17L2/SREBF2/FYN/BARD1	71
BP	GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	109/4749	361/18670	0.02234	0.1335	0.1086	CXCL13/EBI3/IL1B/IRF7/CD1E/IL18/RELB/NLRP3/ICAM1/IL18BP/IL10/BATF/IL1R1/EXO1/CD80/PTPN6/IRF4/BCL3/TLR8/BCL6/CTSH/TREX1/TNFSF4/TFRC/CEACAM1/ULBP2/HMGB1/NFKB2/TNF/MSH6/CD1A/TLR4/MTOR/FOXP3/RAET1E/CD1C/STAT3/IL4R/RSAD2/SMAD7/SWAP70/CCR6/RIPK3/CCR2/HLA-H/C1QB/HLA-G/TP53BP1/BTK/CLU/CD1B/HAVCR2/CD74/HPRT1/CD1D/CLEC4G/LY9/HLX/JAG1/RORC/PTPRC/TRPM4/HLA-E/RFTN1/DUSP22/SUPT6H/MICA/IL12RB1/AICDA/IL27RA/SLA2/RNF8/ARG1/CD19/LTA/IL18R1/RAB27A/CD46/UNC13D/CR2/SUSD4/IL7R/APLF/CFI/ZC3H12A/SERPING1/TRAF2/TNFSF13/IL4/BTN3A2/RIPK2/TNFRSF1B/ULBP1/C1QA/C1R/MAD2L2/C1QBP/TRAF6/C6/FZD5/POU2F2/TGFB1/WAS/JAK3/GATA3/P2RX7/ERCC1/RNF168/IL23A	109
BP	GO:0140053	mitochondrial gene expression	53/4749	162/18670	0.02241	0.1338	0.1089	MRPL37/MRPL28/MRPL51/MRPS36/MRPL22/PPARGC1B/MRPL18/MRPS5/MRPS18C/MRPS11/NSUN4/NOA1/MRPS6/FASTKD2/COA3/MRPL20/PUS1/MRPL50/TRMT10B/MRPL36/MRPS2/TRUB2/MRPL35/MRPL27/YARS2/MRPL15/TRIT1/MRPS25/MRPL34/LARS2/MRPS14/MRPL13/MTG1/PTCD3/FASTKD3/LRPPRC/GADD45GIP1/MRPL10/TRMT10C/MRPL54/DAP3/C1QBP/MRPL2/TBRG4/NGRN/MRPL39/TFB2M/MRPL43/TUFM/TRNT1/MRPL48/MALSU1/GFM1	53
BP	GO:0030183	B cell differentiation	44/4749	131/18670	0.02247	0.1339	0.1089	HMGB3/IL10/NTRK1/PTPN6/BCL3/BCL6/BAX/ITM2A/CMTM7/ITFG2/BTK/RBPJ/LYL1/FLT3/LGALS1/PPP2R3C/ZFP36L2/CD79B/PTPRC/CYLD/NFAM1/KLF6/BAK1/AICDA/PLCL2/CD19/CR2/IL7/POLM/SFRP1/CARD11/IL4/NHEJ1/FZD9/ZFP36L1/HDAC9/ATP11C/DLL1/ATM/POU2F2/RAG2/JAK3/MIR17HG/BAD	44
BP	GO:0001974	blood vessel remodeling	18/4749	45/18670	0.02249	0.1339	0.1089	LIF/CEACAM1/NOL3/BAX/CCR2/TGM2/CST3/AXL/RBPJ/JAG1/BAK1/ACVR2B/EPAS1/FLT4/RSPO3/FGF8/BCR/TGFB1	18
BP	GO:0002820	negative regulation of adaptive immune response	18/4749	45/18670	0.02249	0.1339	0.1089	PTPN6/BCL6/TNFSF4/CEACAM1/FOXP3/IL4R/SMAD7/HLA-G/SAMSN1/HAVCR2/CLEC4G/PTPRC/DUSP22/IL27RA/ARG1/IL7R/ZC3H12A/JAK3	18
BP	GO:0001505	regulation of neurotransmitter levels	107/4749	354/18670	0.02274	0.1352	0.11	IL1B/SLC29A2/ICAM1/KLF2/ADORA2A/IL10/SLC1A1/ACP5/KLF4/RAC1/PPFIA4/PTGIS/SIRPA/RIMS3/CDK5/CLEC7A/SYN1/SYNGR3/TNF/TLR4/NCS1/CHRNA5/DDAH2/SLC29A1/MTOR/SDS/STX11/TSPO/HCRT/BLOC1S6/P2RX1/ABAT/MOXD1/SYT4/GLDC/SNAP47/HTR2A/CLU/CAMK2A/SLC22A3/PPT1/SARDH/SNAP29/PKD2/PFN2/PER2/NQO1/GCAT/APBA2/STX1B/CD47/AIF1/TLR2/DVL1/FLOT1/SCRIB/BHMT/GCHFR/STX19/DRD1/ATP2B4/SNAP23/DTNBP1/WNT7A/PPFIA3/CNR1/NTSR1/TLR6/PARK7/FMR1/SYT11/TACR2/DPYD/ZC3H12A/TPH1/ERC2/SNAPIN/NAPB/MCTP2/CD34/POR/KCNC4/STX2/HBB/RPH3A/DOC2B/CHRNA3/PRKCB/P2RY1/INSR/SYN2/CACNB2/ALDH7A1/AMT/FBXL20/ALDH9A1/SPR/LIN7C/ALDH5A1/SV2A/KLRK1/PDZD11/P2RX7/CX3CR1/KHSRP/TRIM9/SLC44A1	107
BP	GO:0032418	lysosome localization	27/4749	74/18670	0.0229	0.136	0.1106	NR4A3/MAP6/FES/LGALS9/S100A13/PLEKHM2/GAB2/MILR1/IL4R/HMOX1/BTK/BLOC1S1/VPS33B/TMEM106B/LAT/SNAP23/PLEKHM1/UNC13D/RAC2/TFEB/RABGEF1/IL13/SNAPIN/MYH9/FER/SPHK2/RAB34	27
BP	GO:0009266	response to temperature stimulus	76/4749	243/18670	0.02291	0.136	0.1106	PLAC8/CDKN1A/PPARG/HSPA2/NTRK1/SEC13/EPHB1/DNAJA1/TGFB1I1/YWHAE/THRA/ACOT11/HSPA5/HSPA1A/NUP98/CXCL10/MTOR/BAG4/HMOX1/HSPA9/VCP/HTR2A/CAMK2A/MYOF/NUP153/EIF2B3/CIRBP/FOXO1/DNAJA3/HSF2/ST8SIA1/CHORDC1/HSF4/MICA/PIRT/NUP88/STAC/IRAK1/TP53INP1/SUMO1/NTSR1/CAMK2G/NFKBIA/POM121C/NUP205/RAE1/MMP24/NUP50/BAG3/HSPA6/BAG2/DNAJB6/ADM/EIF2AK3/CAMK2D/CD34/MAPKAPK2/HSPA1L/GCLC/ATR/HSPA14/NUP93/DNAJB4/NUP35/RBM3/FOS/ATM/AAAS/METRNL/MAPK1/SLC12A5/NUP62/LRP11/SEH1L/MLST8/SIRT1	76
BP	GO:0030888	regulation of B cell proliferation	23/4749	61/18670	0.02298	0.1363	0.1109	IL21/CDKN1A/IL10/BCL6/TIRAP/TFRC/MZB1/TNFRSF4/TLR4/TNFRSF21/CTLA4/BTK/CD74/PTPRC/TNFRSF13B/MNDA/IL7/IL13/CARD11/IL4/TYROBP/ATM/SLC39A10	23
BP	GO:1901800	positive regulation of proteasomal protein catabolic process	36/4749	104/18670	0.02306	0.1365	0.1111	RNF144A/AURKA/TRIB1/CBFA2T3/HSPA1A/PLK2/ECSCR/PLK1/DET1/SMAD7/VCP/CLU/HERPUD1/RNF40/SGTA/PIAS1/BCAP31/DVL1/GBA/SUMO1/RNF19B/FMR1/RAD23A/EDEM2/USP5/GSK3A/UBQLN2/BAG2/SIRT2/ZFAND2A/GCLC/NUPR1/OSBPL7/PSMD10/DNAJB2/TRIB3	36
BP	GO:0006284	base-excision repair	17/4749	42/18670	0.02316	0.1365	0.1111	SIRT6/APEX2/MPG/NEIL3/FEN1/PARP2/POLQ/RPS3/POLE/XRCC1/DNA2/FAM168A/NEIL1/XPA/OGG1/WRN/MUTYH	17
BP	GO:0031057	negative regulation of histone modification	17/4749	42/18670	0.02316	0.1365	0.1111	TWIST1/SPI1/SKI/UBE2B/FOXP3/SMARCB1/BCOR/SUPT6H/MLLT6/TAF7/KDM5A/SPHK2/CTBP1/KDM4C/ZNF451/USP17L2/SIRT1	17
BP	GO:0042149	cellular response to glucose starvation	17/4749	42/18670	0.02316	0.1365	0.1111	MTMR3/HSPA5/PMAIP1/ITFG2/ATF4/NUAK2/ASNS/PICK1/C12orf66/MYBBP1A/ZC3H12A/IFI16/PIK3C3/EIF2AK3/RRP8/PIK3R4/SESN2	17
BP	GO:0051900	regulation of mitochondrial depolarization	10/4749	21/18670	0.02316	0.1365	0.1111	MLLT11/ABCD1/TSPO/SRC/IFI6/PPP2R3C/CCK/FZD9/GCLC/P2RX7	10
BP	GO:0060713	labyrinthine layer morphogenesis	10/4749	21/18670	0.02316	0.1365	0.1111	IL10/ST14/SOCS3/SPINT1/DNAJB6/ADM/RSPO3/ZFP36L1/FZD5/GCM1	10
BP	GO:1990778	protein localization to cell periphery	95/4749	311/18670	0.02317	0.1365	0.1111	SAPCD2/GPSM2/TTC7A/ANLN/RAB31/SQSTM1/ITGA3/TSPAN5/CDK5/ANXA2P2/BBS2/LGALS3/GORASP1/PTCH1/RTKN/TNF/AKAP5/ANK1/TTC7B/PLK1/ANXA2/MYADM/DCHS1/ZFYVE27/RANGRF/BAG4/MYO5A/GRIPAP1/SEC16A/NUMA1/RHOG/CLIP3/PLS1/SNAP47/RAB13/GGA2/RAB3D/TMEM150A/NUBP1/PTPN9/ATP1B1/STX1B/SMURF1/SPTBN1/FGF13/EZR/MPP5/CLASP2/LRRC15/RILPL2/PRKCI/STAC3/FLOT1/SCRIB/S100A10/LRP1/STAC/EFCAB7/ATP1B3/PRKCE/VAMP3/ADAM22/WDR19/EPB41L2/BCL2L1/AP4M1/BSG/RAPGEF2/FAM126B/PIGW/VTI1B/ADIPOQ/PRNP/LDLRAP1/EPB41/GOPC/TESC/LRP6/PACSIN1/P2RY1/RAB15/ARF6/RAB34/ANKRD9/CACNB2/ARL3/LIN7C/EHD3/PIP5K1A/TGFB1/CNST/LAMA5/PDZD11/SLMAP/ACTB	95
BP	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	30/4749	84/18670	0.02331	0.1373	0.1117	VEGFA/BIRC5/ADORA2A/MICAL1/KLF4/PLAUR/RFFL/MMP9/YWHAE/NOL3/TNFAIP8/GPX1/SRC/IFI6/PRDX3/SFN/CFLAR/ARRB1/HERPUD1/PRDX5/PARK7/TFAP2B/BCL2L12/CD44/SIAH2/BIRC3/DNAJB6/POR/BIRC7/PAK2	30
BP	GO:0051091	positive regulation of DNA-binding transcription factor activity	81/4749	261/18670	0.02337	0.1375	0.1119	IL1B/VEGFA/IL18/PPARG/NLRP3/ICAM1/FOSL1/IL10/NTRK1/SRF/TIRAP/LGALS9/NFKB2/TNF/LRP8/HSPA1A/CD200/TLR4/TRIM25/TRIM26/WNT10B/SMARCB1/CRTC2/STAT3/RIPK3/PRDX3/PPARGC1B/ARHGEF5/ARHGEF2/TP53BP1/CFLAR/TRIM62/BTK/CLU/CAMK2A/UBB/ARID5B/CRTC1/UBE2N/RPS3/CTH/IRAK3/TRIM22/RPS27A/CARM1/SMARCA4/PINK1/STK3/NFAM1/PRKCI/UBA52/TLR2/TRIM13/FLOT1/NOD2/IRAK1/DDIT3/DHX33/IL18R1/TLR6/MID2/PARK7/TAB1/TRAF1/TRIM52/TRAF2/CARD11/S100A8/RIPK2/ESR1/FER/PPRC1/LRP6/PRKCB/MBTPS2/TRAF6/TNFSF11/TGFB1/CX3CR1/TRIM15/TRIM5	81
BP	GO:0000187	activation of MAPK activity	50/4749	152/18670	0.02349	0.1378	0.1121	IQGAP3/IL1B/MAPK11/TP73/CDK1/FPR1/DUSP6/TNF/ADRA2B/TLR4/PTPN1/PEA15/MAP3K6/MAP2K3/DUSP5/ARRB1/MAP3K2/NTRK3/UBB/TGFB3/CD74/UBE2N/MAP2K6/RPS27A/PAK3/MAP3K5/PTPRC/ITGA1/UBA52/NOD2/MAP3K11/IRAK1/TAB1/MAP2K4/GHRL/MAP4K1/ERN1/RIPK2/MAPKAPK2/INSR/TRAF6/BIRC7/TNFSF11/NTF3/MAP3K9/SHC2/MAPK1/P2RX7/SHC1/AVPI1	50
BP	GO:0048489	synaptic vesicle transport	50/4749	152/18670	0.02349	0.1378	0.1121	ADORA2A/RIMS3/CDK5/SYN1/NCS1/CHRNA5/STX11/BLOC1S6/P2RX1/SYT4/SNAP47/HTR2A/BLOC1S1/CAMK2A/CNIH2/SNAP29/PFN2/SLC2A4/BLOC1S4/APBA2/STX1B/PINK1/DVL1/AP3D1/SCRIB/STX19/DRD1/SNAP23/DTNBP1/RAB27A/WNT7A/PPFIA3/CNR1/FMR1/SYT11/AP3M2/ERC2/SNAPIN/NAPB/DNM1/STX2/DOC2B/PRKCB/P2RY1/CACNB2/FBXL20/AP3B2/SV2A/P2RX7/TRIM9	50
BP	GO:0097480	establishment of synaptic vesicle localization	50/4749	152/18670	0.02349	0.1378	0.1121	ADORA2A/RIMS3/CDK5/SYN1/NCS1/CHRNA5/STX11/BLOC1S6/P2RX1/SYT4/SNAP47/HTR2A/BLOC1S1/CAMK2A/CNIH2/SNAP29/PFN2/SLC2A4/BLOC1S4/APBA2/STX1B/PINK1/DVL1/AP3D1/SCRIB/STX19/DRD1/SNAP23/DTNBP1/RAB27A/WNT7A/PPFIA3/CNR1/FMR1/SYT11/AP3M2/ERC2/SNAPIN/NAPB/DNM1/STX2/DOC2B/PRKCB/P2RY1/CACNB2/FBXL20/AP3B2/SV2A/P2RX7/TRIM9	50
BP	GO:0033683	nucleotide-excision repair, DNA incision	16/4749	39/18670	0.02375	0.1389	0.113	DDB2/UBB/RFC2/RPS27A/UBA52/POLD4/ERCC5/ERCC2/GTF2H2/GTF2H1/GTF2H5/XPA/OGG1/FAN1/CUL4A/ERCC1	16
BP	GO:0072595	maintenance of protein localization in organelle	16/4749	39/18670	0.02375	0.1389	0.113	BCL3/HK1/CDK5/PML/HSPA5/HK2/TSPO/KDELR2/SUN2/PINK1/INSIG1/PARK7/TOPORS/ARL2BP/ARL2/BARD1	16
BP	GO:1902229	regulation of intrinsic apoptotic signaling pathway in response to DNA damage	16/4749	39/18670	0.02375	0.1389	0.113	SKIL/ZNF385A/SNAI1/RPL26/CLU/CD74/RPS3/BID/TAF9B/MUC1/BCL2L12/CD44/BCL2L1/PIAS4/RAD9A/SIRT1	16
BP	GO:1903362	regulation of cellular protein catabolic process	77/4749	247/18670	0.02389	0.1397	0.1136	PBK/RNF144A/FURIN/AURKA/TRIB1/ANXA2P2/PML/CBFA2T3/HSPA1A/PLK2/ECSCR/PLK1/DET1/ANXA2/LDLR/GPX1/WNT10B/SMAD7/RYBP/RPL5/VCP/SDCBP/ATP13A2/CLU/USP19/UBB/MAGEF1/HERPUD1/MYLIP/PSMF1/N4BP1/UBXN1/RNF40/PDCL3/SGTA/SMURF1/RPL23/PINK1/UBE2G2/PIAS1/EZR/BCAP31/ATRAID/RAD23B/DVL1/LRP1/GBA/SUMO1/RNF19B/PARK7/FMR1/UBE3A/RAD23A/SCO1/EDEM2/USP5/UCHL5/GSK3A/PSME2/BRSK2/BTRC/UBQLN2/BAG2/SIRT2/ZFAND2A/RNF139/GCLC/MAP1A/NUPR1/OSBPL7/RPL11/PSMD10/GLMN/TMF1/DNAJB2/UBAC2/TRIB3	77
BP	GO:0030832	regulation of actin filament length	58/4749	180/18670	0.02397	0.1399	0.1138	CDC42EP4/PLEKHG2/ICAM1/CIT/HCK/CYFIP1/SNX9/CAPZB/GSN/CTTN/MTOR/MYADM/BAG4/CDC42EP1/SWAP70/TMOD2/TENM1/CAPG/CORO1B/PDXP/WHAMMP3/ADD3/PFN2/HIP1R/ARHGAP35/ARPC1B/PAK3/PREX1/PICK1/TMSB4Y/SPTBN1/CORO1A/VASP/TRIOBP/TWF2/CFL1/COTL1/SPTAN1/ARPC5/MKKS/CAPZA1/PRKCE/ACTR3B/KANK3/WDR1/TMSB15A/VILL/FER/ARF6/ARHGAP18/WHAMM/AP1AR/C15orf62/SEMA5A/WAS/FMN1/ADD2/RAC3	58
BP	GO:0035306	positive regulation of dephosphorylation	22/4749	58/18670	0.02404	0.1399	0.1138	ITGA2/SPPL3/MTOR/RIPK3/SRC/CDCA2/PPARGC1B/PTBP1/CD33/PINK1/MTMR9/PTPRC/ITGA1/LILRB2/GBA/PPP1R16B/CAMTA1/PPP1R15A/SLC39A10/TGFB1/PPP1R12A/CDH5	22
BP	GO:0034162	toll-like receptor 9 signaling pathway	11/4749	24/18670	0.02411	0.1399	0.1138	GRAMD4/TLR8/UNC93B1/HMGB1/RSAD2/HAVCR2/IRAK1/PIK3C3/PTPRS/TRAF6/PIK3R4	11
BP	GO:0036315	cellular response to sterol	11/4749	24/18670	0.02411	0.1399	0.1138	PTCH1/LRP8/GRAMD1C/RORC/GRAMD1B/ABCA1/INSIG1/LRP6/OSBPL7/GRAMD1A/CYP7A1	11
BP	GO:0046426	negative regulation of JAK-STAT cascade	11/4749	24/18670	0.02411	0.1399	0.1138	BCL3/NF2/PPP2R1A/SOCS2/PARP14/SOCS3/PPP2CA/ADIPOR1/HGS/GGNBP2/PIBF1	11
BP	GO:0046835	carbohydrate phosphorylation	11/4749	24/18670	0.02411	0.1399	0.1138	HK1/PFKFB3/HK2/PFKFB4/GNE/GALK2/GALK1/PFKFB2/FGGY/IPPK/NAGK	11
BP	GO:0071677	positive regulation of mononuclear cell migration	11/4749	24/18670	0.02411	0.1399	0.1138	CCR1/LGALS3/HMGB1/TNF/CXCL10/SERPINE1/CCR2/AIF1/FPR2/TGFB1/CCL27	11
BP	GO:0099563	modification of synaptic structure	11/4749	24/18670	0.02411	0.1399	0.1138	CYFIP1/CHMP2B/MYH10/CAMKV/GRIPAP1/TIAM1/DLGAP3/PFN2/FMR1/STAU1/CDC42	11
BP	GO:0002755	MyD88-dependent toll-like receptor signaling pathway	15/4749	36/18670	0.02423	0.14	0.1139	IRF7/TLR8/TIRAP/TLR4/BTK/UBB/IRAK3/RPS27A/CD300LF/UBA52/TLR2/IRAK1/TLR6/TAB1/TRAF6	15
BP	GO:0009112	nucleobase metabolic process	15/4749	36/18670	0.02423	0.14	0.1139	MTHFD1L/ACPP/TYMP/TYMS/DHODH/MTOR/RRM1/HPRT1/MTHFD1/DPYD/APRT/CMPK1/CTPS2/PRPS1/MAPK1	15
BP	GO:0035872	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	15/4749	36/18670	0.02423	0.14	0.1139	HSPA1A/TLR4/UBB/UBE2N/MAP2K6/RPS27A/CYLD/UBA52/NOD2/IRAK1/TAB1/NFKBIA/BIRC3/RIPK2/TRAF6	15
BP	GO:0045740	positive regulation of DNA replication	15/4749	36/18670	0.02423	0.14	0.1139	E2F7/E2F8/CDK1/CDT1/RAC1/DBF4/TNFAIP1/DBF4B/CDK2/CTC1/JUN/MAP2K4/DNA2/KCTD13/WIZ	15
BP	GO:0090218	positive regulation of lipid kinase activity	15/4749	36/18670	0.02423	0.14	0.1139	SRC/DGKZ/AMBRA1/FLT3/VAV2/NOD2/CD19/FLT1/FPR2/AGAP2/EEF1A2/PIK3R4/TNFAIP8L3/TGFB1/PDGFB	15
BP	GO:0034440	lipid oxidation	35/4749	101/18670	0.02437	0.1406	0.1144	TWIST1/NR4A3/PPARG/MTOR/ABCD1/MECR/ABCD2/SLC27A2/MCAT/ACOX2/TYSND1/ACOT8/ADIPOR2/ADIPOR1/PRKAG2/CNR1/AMACR/ETFA/PEX2/BDH2/ADIPOQ/CPT1A/POR/DGAT2/ACACB/ETFB/ACAD11/ECI1/PECR/PPARD/CYP4V2/PEX13/HADHB/SESN2/DECR2	35
BP	GO:0030808	regulation of nucleotide biosynthetic process	40/4749	118/18670	0.02457	0.1407	0.1144	PDPR/SEC13/TREX1/PFKFB3/ENO1/PGAM1/CBFA2T3/SIRT6/NUP98/ENTPD5/DNAJC30/STAT3/VCP/HTR2A/PFKFB4/NUP153/GUCA1C/PINK1/DDIT4/PFKFB2/NUP88/PRKAG2/POM121C/AK4/NUP205/RAE1/NUP50/IL4/INSR/NUPR1/SPHK2/NUP93/NUP35/AAAS/TAZ/GSTZ1/NUP62/P2RX7/SEH1L/NCOR1	40
BP	GO:0036003	positive regulation of transcription from RNA polymerase II promoter in response to stress	14/4749	33/18670	0.02457	0.1407	0.1144	VEGFA/NOTCH1/KLF2/ATF3/HSPA5/RBPJ/ATF4/HSF2/MUC1/HSF4/DDIT3/CEBPB/MBTPS2/SESN2	14
BP	GO:0045191	regulation of isotype switching	14/4749	33/18670	0.02457	0.1407	0.1144	IL10/BCL6/TNFSF4/TFRC/FOXP3/TP53BP1/PTPRC/SUPT6H/IL27RA/APLF/TNFSF13/IL4/MAD2L2/TGFB1	14
BP	GO:1901797	negative regulation of signal transduction by p53 class mediator	14/4749	33/18670	0.02457	0.1407	0.1144	TWIST1/DYRK3/ZNF385A/RFFL/RRM2B/SNAI1/CD74/TAF9B/MUC1/BDKRB2/BCL2L12/CD44/PSMD10/SIRT1	14
BP	GO:0030811	regulation of nucleotide catabolic process	29/4749	81/18670	0.02458	0.1407	0.1144	SEC13/TREX1/PFKFB3/PGAM1/CBFA2T3/SIRT6/NUP98/ENTPD5/STAT3/HTR2A/PFKFB4/NUP153/DDIT4/PFKFB2/NUP88/PRKAG2/POM121C/NUP205/RAE1/NUP50/INSR/NUPR1/NUP93/NUP35/AAAS/NUP62/P2RX7/SEH1L/NCOR1	29
BP	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	29/4749	81/18670	0.02458	0.1407	0.1144	RNF144A/AURKA/TRIB1/CBFA2T3/HSPA1A/PLK2/PLK1/DET1/SMAD7/VCP/CLU/HERPUD1/SGTA/PIAS1/BCAP31/DVL1/GBA/SUMO1/RNF19B/RAD23A/USP5/GSK3A/UBQLN2/SIRT2/ZFAND2A/GCLC/PSMD10/DNAJB2/TRIB3	29
BP	GO:0033238	regulation of cellular amine metabolic process	29/4749	81/18670	0.02458	0.1407	0.1144	ABAT/PSMD8/ATCAY/PSMD1/PSMD2/HPRT1/PSMF1/NQO1/OAZ3/BHMT/DRD1/PSMD9/ATP2B4/PSMA5/PARK7/PSMB7/OAZ2/PSMD5/PSME2/PSMB5/PSMB4/PSMA3/OAZ1/PSMD10/PSMB1/PSMD7/PSMB3/PSMC5/PSMD11	29
BP	GO:0009649	entrainment of circadian clock	12/4749	27/18670	0.02459	0.1407	0.1144	ARNTL2/PML/PPP1CB/CRY1/PER2/CRTC1/BHLHE40/RBM4B/PHLPP1/GNAQ/MTA1/PER3	12
BP	GO:0022616	DNA strand elongation	12/4749	27/18670	0.02459	0.1407	0.1144	MCM4/FEN1/GINS2/GINS1/GINS4/MCM7/RNASEH2A/POLE/MCM3/POT1/DNA2/NUCKS1	12
BP	GO:0090169	regulation of spindle assembly	12/4749	27/18670	0.02459	0.1407	0.1144	GPSM2/SPAG5/SMC3/CHMP2B/HSPA1A/PLK1/NUMA1/CHMP1A/CHMP2A/SMC1A/SENP6/CEP97	12
BP	GO:0043171	peptide catabolic process	13/4749	30/18670	0.02471	0.1409	0.1146	ANPEP/CHAC1/CTSH/TPP1/CHAC2/GGT1/CPQ/ADAMTS13/GGTLC2/NAALADL1/ERAP1/GGT7/LNPEP	13
BP	GO:0046596	regulation of viral entry into host cell	13/4749	30/18670	0.02471	0.1409	0.1146	LGALS9/GSN/TRIM25/TRIM26/FCN1/IFITM2/TRIM62/CD74/LGALS1/IFITM3/IFITM1/MID2/TRIM5	13
BP	GO:0048147	negative regulation of fibroblast proliferation	13/4749	30/18670	0.02471	0.1409	0.1146	PPARG/SKI/BAX/TP53INP1/LTA/EMD/PEX2/FTH1/NLRC3/SFRP1/NUPR1/B4GALT7/FBXO4	13
BP	GO:0061157	mRNA destabilization	13/4749	30/18670	0.02471	0.1409	0.1146	ZFP36/ZC3H12D/PLEKHN1/UPF1/ZFP36L2/MEX3D/RBM23/ZC3H12A/YTHDF3/METTL16/GIGYF2/ZFP36L1/KHSRP	13
BP	GO:2000058	regulation of ubiquitin-dependent protein catabolic process	49/4749	149/18670	0.02484	0.1414	0.1151	PBK/RNF144A/AURKA/TRIB1/PML/CBFA2T3/HSPA1A/PLK2/PLK1/DET1/WNT10B/SMAD7/RYBP/RPL5/VCP/SDCBP/CLU/MAGEF1/HERPUD1/N4BP1/UBXN1/PDCL3/SGTA/SMURF1/RPL23/PIAS1/BCAP31/RAD23B/DVL1/GBA/SUMO1/RNF19B/PARK7/UBE3A/RAD23A/USP5/UCHL5/GSK3A/UBQLN2/SIRT2/ZFAND2A/RNF139/GCLC/MAP1A/RPL11/PSMD10/GLMN/DNAJB2/TRIB3	49
BP	GO:0070997	neuron death	105/4749	348/18670	0.02502	0.1423	0.1158	EGR1/KIF14/TYRO3/NR4A3/CASP9/ADORA2A/NTRK2/CIT/IL10/FAIM2/NTRK1/GAPDH/EPHB1/GRN/CNTF/VSTM2L/MYBL2/MCL1/CDK5/GPNMB/TP63/STAMBP/ASCL1/HSPA5/TNF/CSF1/FOXB1/CD200/TLR4/USP53/BAX/TNFRSF21/MTOR/STAT3/SORL1/HMOX1/PARP2/ARRB1/CCL3/ATP13A2/CLU/UBB/AXL/TGFB3/PPT1/ATF4/AMBRA1/CCL2/NQO1/PAK3/BID/MAP3K5/PINK1/NAMPT/CORO1A/DDIT4/ITGA1/PRKCI/ZNF746/MAP3K11/LRP1/GBA/DDIT3/TLR6/CHP1/PARK7/ELK1/JUN/TFAP2B/PPP5C/AGAP2/CTSZ/CEBPB/BCL2L1/MAP2K4/IL13/TRAF2/CD34/PRNP/TNFRSF1B/F2R/NAE1/TYROBP/C1QA/FZD9/GCLC/MAX/NUPR1/FGF8/NEFL/NTF3/FOS/ATM/ATG7/POU4F1/NMNAT1/ADNP/GATA3/CX3CR1/BAD/RRAS2/FYN/ILK/PIGT/SIRT1	105
BP	GO:0046916	cellular transition metal ion homeostasis	37/4749	108/18670	0.02525	0.1434	0.1167	TTC7A/ATP6V0D1/TFRC/SCO2/SLC39A7/TMPRSS6/MT1E/MT2A/FXN/HMOX1/ATP13A2/SRI/HEPH/NUBP1/MT1X/ATP6V1A/AP3D1/MT1H/FTL/MT1G/ACO1/NCOA4/FTH1/SCO1/ATP6V1G1/S100A8/PRNP/ISCU/MT1A/HMOX2/CYBRD1/MT1B/MT1M/SLC39A10/CCDC115/SLC40A1/MT1F	37
BP	GO:0060071	Wnt signaling pathway, planar cell polarity pathway	37/4749	108/18670	0.02525	0.1434	0.1167	RAC1/VANGL1/NKD1/TIAM1/CTHRC1/PSMD8/DVL3/PSMD1/PSMD2/FZD6/PTK7/PSMF1/SMURF1/DVL1/PSMD9/AP2S1/PSMA5/WNT7A/PSMB7/PSMD5/PSME2/SFRP1/RSPO3/PSMB5/MLLT3/PSMB4/PSMA3/MED12/PARD6A/FZD5/PSMD10/CDC42/PSMB1/PSMD7/PSMB3/PSMC5/PSMD11	37
BP	GO:0016239	positive regulation of macroautophagy	25/4749	68/18670	0.02533	0.1437	0.1169	GPSM1/BNIP3L/HMOX1/PIM2/HTT/FYCO1/CALCOCO2/SMURF1/PINK1/TRIM13/ULK1/KIAA1324/BAG3/UVRAG/LACRT/IL4/RIPK2/LRSAM1/PIP4K2A/VPS13D/RALB/PIP4K2B/SESN2/RAB12/SIRT1	25
BP	GO:0032535	regulation of cellular component size	111/4749	370/18670	0.02555	0.1448	0.1178	IQGAP3/CDC42EP4/VEGFA/PLEKHG2/ICAM1/CIT/SRF/HCK/RAC1/CYFIP1/CDK5/SPP1/SEMA4C/SNX9/TNFRSF12A/CAPZB/SEMA7A/GSN/CTTN/AKT3/MTOR/MYADM/ZFYVE27/SLC12A4/BAG4/SNF8/CDC42EP1/SEMA3G/SWAP70/TMOD2/TENM1/SLC12A2/CAPG/SEMA6C/CORO1B/PLS1/ATP13A2/NTRK3/PDXP/WHAMMP3/PAK1/ADD3/PFN2/SEMA6B/HIP1R/ARHGAP35/ARPC1B/PAK3/PREX1/PICK1/TMSB4Y/SPTBN1/VAV2/FGF13/EZR/CORO1A/ARHGAP4/VASP/TRIOBP/TWF2/L1CAM/CFL1/KCNN4/COTL1/SPTAN1/ARPC5/MKKS/LRP1/LIMK1/TTL/WNT7A/CAPZA1/PRKCE/DEPTOR/IL7R/ACTR3B/KANK3/WDR1/SEMA3B/IST1/SEMA5B/TMSB15A/VILL/RAP1GAP2/FER/PTPRS/PRR16/LAMTOR4/PEX11A/SEMA4D/ARF6/ARHGAP18/SLC12A6/PPP1R15A/NEFL/WHAMM/AP1AR/RUFY3/C15orf62/SEMA5A/WAS/RTN4R/ADNP/TRPC5/SLC12A5/FMN1/GDI1/P2RX7/ADD2/ILK/RAC3	111
BP	GO:0034504	protein localization to nucleus	81/4749	262/18670	0.02558	0.1449	0.1179	LIF/GTSE1/TXNIP/CDK1/CDKN1A/BCL3/GBP2/CDK5/YWHAE/RBM22/NF2/PML/KPNA2/NUP98/RGPD2/PLK1/MMP12/LMNA/STAT3/MSX1/CSE1L/SRC/DTX3L/LILRB4/GLIS2/FGF9/NUP153/SUN2/TMCO6/PIKFYVE/CCT5/BYSL/RPL23/DVL1/DRD1/NUP88/OTUD7B/NOLC1/RANBP6/SUMO1/FAM53B/CHP1/PARK7/EFCAB7/KPNA3/TOPORS/NFKBIA/MCRS1/CABP1/POM121C/ECT2/ARNTL/NUP50/ZC3H12A/BAG3/FAM53A/WRAP53/RAB23/DNAJB6/CD2AP/EIF2AK3/POM121L2/ARL2BP/PYGO1/SNUPN/NUP93/RPL11/XPA/ARL2/NUP35/WRN/TGFB1/RGPD1/MAPK1/NUP62/TNPO1/SESN2/FBXO4/FYN/BARD1/CCT3	81
BP	GO:0042552	myelination	44/4749	132/18670	0.02561	0.1449	0.1179	EGR2/KIF14/NTRK2/TYMP/GPC1/CD9/SKI/TNFRSF21/MTOR/ABCD1/ITGAX/MYO5A/FA2H/ABCD2/NAB2/CLU/AMIGO1/NTRK3/PIKFYVE/SBF2/MPP5/NDRG1/MARVELD1/TLR2/ZNF24/NAB1/ERCC2/ERBB2/ADAM22/PMP22/POU3F1/B4GALT5/SIRT2/CMTM8/EIF2AK3/TNFRSF1B/DICER1/GALC/HEXB/ATRN/NKX6-2/TGFB1/RARA/ILK	44
BP	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	34/4749	98/18670	0.02576	0.1456	0.1184	KIF2C/KIF4A/KIF15/KIF23/SEC13/RACGAP1/KIF18A/IFI30/SEC24D/CAPZB/HLA-DQB2/KIF11/HLA-DMA/KLC1/CENPE/KIF4B/CD74/CTSF/DCTN5/HLA-DPA1/HLA-DRA/AP1S1/AP2S1/CTSD/LAG3/CAPZA1/KIF3C/HLA-DMB/HLA-DQA2/ACTR1A/CANX/HLA-DPB1/TRAF6/HLA-DRB1	34
BP	GO:0002449	lymphocyte mediated immunity	106/4749	352/18670	0.02577	0.1456	0.1184	IL1B/IRF7/CD1E/IL18/IL21/NLRP3/ICAM1/IL10/BATF/IL1R1/EXO1/PTPN6/BCL3/TLR8/BCL6/CTSH/TREX1/TNFSF4/TFRC/CEACAM1/LGALS9/ULBP2/HMGB1/TNF/MSH6/CD1A/FOXP3/RAET1E/CD1C/TUBB/IL4R/RSAD2/SMAD7/SWAP70/CCR6/RIPK3/CCR2/HLA-H/C1QB/HLA-G/TP53BP1/SH2D1A/BTK/CLU/CD1B/HAVCR2/TUBB4B/CD74/HPRT1/CD1D/CLEC4G/JAG1/PTPRC/CORO1A/TRPM4/HLA-E/RFTN1/DUSP22/SUPT6H/MICA/IL12RB1/AICDA/IL27RA/SLA2/RNF8/ARG1/CD19/LAG3/CADM1/LTA/IL18R1/RAB27A/CD46/UNC13D/CR2/SUSD4/CRK/IL7R/APLF/CFI/SERPING1/TRAF2/LAMP1/TNFSF13/IL4/BTN3A2/TNFRSF1B/ULBP1/C1QA/C1R/MAD2L2/C1QBP/TRAF6/C6/FZD5/POU2F2/TGFB1/WAS/KLRK1/CD96/GATA3/P2RX7/PRDX1/ERCC1/RNF168/IL23A	106
BP	GO:0009620	response to fungus	20/4749	52/18670	0.0262	0.1472	0.1198	IL17A/GAPDH/CLEC7A/TLR4/CARD9/BTK/RNASE8/COTL1/BAK1/ARG1/IL17RC/CRK/DEFB114/MPO/HTN3/RARRES2/S100A8/DEFA1B/DEFA4/TGFB1	20
BP	GO:0032731	positive regulation of interleukin-1 beta production	20/4749	52/18670	0.0262	0.1472	0.1198	EGR1/NLRP3/TLR8/HK1/CLEC7A/LGALS9/HMGB1/TLR4/LILRA2/CCL3/NOD2/MNDA/LILRA5/IFI16/RIPK2/TYROBP/CARD8/FZD5/TRIM16/P2RX7	20
BP	GO:0043543	protein acylation	77/4749	248/18670	0.02621	0.1472	0.1198	TWIST1/LIF/IL1B/GTF3C4/IRF4/ESCO2/ZDHHC12/SPI1/CAMK1/DPF3/BRCA2/PHF10/FOXP3/SMARCB1/CRTC2/ING3/NAP1L2/ING5/KANSL3/IWS1/CLIP3/ARRB1/MORF4L2/KANSL1L/OGDH/BLOC1S1/KAT2A/ACTL6A/FOXO1/MDH2/NMT1/TAF1L/YEATS4/SUPT3H/DSCC1/DLST/TAF9B/MUC1/ZDHHC24/TAF6L/TAF10/NAA16/PARK7/CHEK1/MCRS1/ZDHHC3/NAT9/ARNTL/LACRT/CDYL/BRPF3/TAF7/KAT6B/ZDHHC4/POR/AANAT/DPF1/ZDHHC9/TADA2A/NUPR1/ZDHHC2/SPHK2/ZDHHC7/CTBP1/PORCN/ZDHHC16/TGFB1/ZNF451/TRIM16/LDB1/GATA3/CPA4/TADA1/HINT2/KAT6A/MAGEA2B/SIRT1	77
BP	GO:0006140	regulation of nucleotide metabolic process	48/4749	146/18670	0.02627	0.1472	0.1198	PPIF/CDK1/PDPR/SEC13/TREX1/PFKFB3/ENO1/PGAM1/CBFA2T3/SIRT6/NUP98/SLC25A23/ENTPD5/ABCD1/DNAJC30/STAT3/TSPO/CCNB1/VCP/HTR2A/PFKFB4/NUP153/GUCA1C/PINK1/DDIT4/PFKFB2/NUP88/PRKAG2/PARK7/POM121C/AK4/NUP205/RAE1/NUP50/IL4/ISCU/INSR/NUPR1/SPHK2/NUP93/NUP35/AAAS/TAZ/GSTZ1/NUP62/P2RX7/SEH1L/NCOR1	48
BP	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	41/4749	122/18670	0.0266	0.1472	0.1198	PBK/RNF144A/AURKA/TRIB1/CBFA2T3/HSPA1A/PLK2/PLK1/DET1/WNT10B/SMAD7/RYBP/VCP/SDCBP/CLU/HERPUD1/N4BP1/UBXN1/SGTA/PIAS1/BCAP31/RAD23B/DVL1/GBA/SUMO1/RNF19B/PARK7/RAD23A/USP5/UCHL5/GSK3A/UBQLN2/SIRT2/ZFAND2A/GCLC/MAP1A/RPL11/PSMD10/GLMN/DNAJB2/TRIB3	41
BP	GO:0000722	telomere maintenance via recombination	7/4749	13/18670	0.02661	0.1472	0.1198	BRCA2/RAD51/XRCC3/XRCC1/SMC5/ERCC1/TERF2	7
BP	GO:0001833	inner cell mass cell proliferation	7/4749	13/18670	0.02661	0.1472	0.1198	BRCA2/PELO/GINS1/GINS4/SALL4/SBDS/PRPF19	7
BP	GO:0002430	complement receptor mediated signaling pathway	7/4749	13/18670	0.02661	0.1472	0.1198	FPR1/FPR3/GPR33/FPR2/C3AR1/CR2/GPR32	7
BP	GO:0006012	galactose metabolic process	7/4749	13/18670	0.02661	0.1472	0.1198	SLC35A2/GLB1/PGM2L1/GALK2/GALK1/GALM/GALT	7
BP	GO:0006670	sphingosine metabolic process	7/4749	13/18670	0.02661	0.1472	0.1198	SGPP1/GBA/ACER1/ACER2/ASAH2/ASAH2B/SPHK2	7
BP	GO:0007183	SMAD protein complex assembly	7/4749	13/18670	0.02661	0.1472	0.1198	PMEPA1/SMAD6/FKBP1A/LDLRAD4/EID2/SMAD1/TGFB1	7
BP	GO:0009313	oligosaccharide catabolic process	7/4749	13/18670	0.02661	0.1472	0.1198	NEU4/GM2A/NEU1/MAN2B1/NEU3/HEXB/MANBA	7
BP	GO:0010745	negative regulation of macrophage derived foam cell differentiation	7/4749	13/18670	0.02661	0.1472	0.1198	PPARG/ABCG1/ABCA1/NFKBIA/ABCA5/ADIPOQ/CETP	7
BP	GO:0030656	regulation of vitamin metabolic process	7/4749	13/18670	0.02661	0.1472	0.1198	VDR/IL1B/TNF/SNAI1/CLYBL/CYP27B1/RDH10	7
BP	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway	7/4749	13/18670	0.02661	0.1472	0.1198	TRIB1/LILRA2/SIGIRR/DEFB114/NFKBIL1/LACRT/CARD8	7
BP	GO:0033004	negative regulation of mast cell activation	7/4749	13/18670	0.02661	0.1472	0.1198	LGALS9/MILR1/HMOX1/CD300LF/CNR1/RABGEF1/FER	7
BP	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein	7/4749	13/18670	0.02661	0.1472	0.1198	NF2/PPP2R1A/PARP14/SOCS3/PPP2CA/GGNBP2/PIBF1	7
BP	GO:0043970	histone H3-K9 acetylation	7/4749	13/18670	0.02661	0.1472	0.1198	SMARCB1/CRTC2/NAP1L2/CHEK1/SPHK2/ZNF451/GATA3	7
BP	GO:0048875	chemical homeostasis within a tissue	7/4749	13/18670	0.02661	0.1472	0.1198	VEGFA/CTSH/HOMER2/HOMER1/RCN3/NAPSA/EPAS1	7
BP	GO:0090239	regulation of histone H4 acetylation	7/4749	13/18670	0.02661	0.1472	0.1198	SPI1/SMARCB1/IWS1/ARRB1/MUC1/CTBP1/SIRT1	7
BP	GO:0090399	replicative senescence	7/4749	13/18670	0.02661	0.1472	0.1198	CDKN1A/SERPINE1/CDKN2A/CHEK1/ATR/CHEK2/ATM	7
BP	GO:0090594	inflammatory response to wounding	7/4749	13/18670	0.02661	0.1472	0.1198	GRN/CCR2/HMOX1/TIMP1/F2R/SIGLEC10/TGFB1	7
BP	GO:0051187	cofactor catabolic process	24/4749	65/18670	0.02662	0.1472	0.1198	CHAC1/GPX1/ABCD1/CHAC2/HMOX1/GGT1/PRDX3/VCP/PDXP/MTHFS/PRDX5/HBA2/GGTLC2/NUDT17/MPO/BLVRA/HBG1/PRDX6/HBB/HMOX2/GGT7/NNT/PRDX1/ASPDH	24
BP	GO:0071806	protein transmembrane transport	24/4749	65/18670	0.02662	0.1472	0.1198	MCL1/HSPA5/TIMM17A/TIMM10/CLU/SEC61A2/TIMM22/TIMM50/ROMO1/TRAM2/SEC61B/GRPEL1/PEX2/PEX5/ZFAND2B/PAM16/BCR/TOMM22/AGK/CHCHD4/PEX13/NDUFA13/TIMM9/PEX1	24
BP	GO:0023061	signal release	136/4749	462/18670	0.02719	0.1501	0.1221	LIF/IL1B/ADORA2A/RAC1/PPFIA4/IL1RN/PIM3/RAB11FIP1/SLC16A1/NMB/RIMS3/CDK5/SPP1/SYN1/TNF/ADRA2B/SCG5/BLK/NCS1/CHRNA5/FFAR2/STX11/MYO5A/HCRT/BLOC1S6/P2RX1/TIAM1/ABAT/SYT4/ARRB1/BTK/SNAP47/GNAS/HTR2A/CAMK2A/ENY2/C2CD2L/SRI/CRY1/PPT1/SNAP29/ENHO/PFN2/PER2/CCKAR/FFAR3/APBA2/CASR/STX1B/TCF7L2/KDM5B/PRKCA/TRPM4/NADK/ANXA5/OXCT1/DVL1/SCRIB/PFKFB2/STX19/DRD1/PSMD9/LRP1/SNAP23/DTNBP1/OSM/CACNA2D2/SIRT3/ILDR1/WNT7A/PPFIA3/CNR1/C1QTNF3/PARK7/TFAP2B/RAB11FIP3/FMR1/ACVR1C/SLC25A5/ACVR2B/SNX19/CAMK2G/SYT11/PRKCE/TACR2/SIDT2/LRP5L/SOX11/ARNTL/GLUD1/ERC2/BRSK2/SNAPIN/NAPB/MCTP2/SFRP1/ADM/GHRL/KCNG2/ADIPOQ/CPT1A/ARL2BP/RAB11FIP5/KCNC4/STX2/SERP1/RPH3A/DOC2B/CHRNA3/PRKCB/FAM3B/P2RY1/SYN2/RAB1A/CACNB2/FBXL20/SLC25A4/PFKL/TNFSF11/ARL2/NPFF/PPARD/SLC9B2/LIN7C/FFAR1/TMF1/SV2A/NDUFAF2/PDZD11/GATA3/PDX1/P2RX7/GIPR/SYBU/BAD/TRIM9	136
BP	GO:0042116	macrophage activation	33/4749	95/18670	0.02723	0.1501	0.1221	CSF2/IL10/TTBK1/TLR8/TREX1/GRN/TNF/CD200/TLR4/LDLR/SBNO2/IL4R/CCL3/CLU/HAVCR2/CD74/NAMPT/PTPRC/AIF1/TLR2/SHPK/TLR6/FPR2/JUN/PRKCE/ZC3H12A/IL13/IFNGR1/TYROBP/C1QA/ATM/CD93/PJA2	33
BP	GO:0045069	regulation of viral genome replication	33/4749	95/18670	0.02723	0.1501	0.1221	NOTCH1/TOP2A/IFIT1/ISG15/APOBEC3H/MX1/TNF/IFIT5/RSAD2/IFITM2/PPIH/BST2/MORC2/OASL/ISG20/TBC1D20/BANF1/IFITM3/AICDA/IFITM1/FMR1/CCNK/RAD23A/ZC3H12A/OAS1/CNOT7/IFI16/ILF3/ZC3HAV1/STAU1/STOM/NUCKS1/SETDB1	33
BP	GO:0003254	regulation of membrane depolarization	19/4749	49/18670	0.02729	0.1501	0.1221	MLLT11/ABCD1/RANGRF/SMAD7/TSPO/SRC/IFI6/SCN1B/PPP2R3C/CCK/TRPM4/NTSR1/CAMK2D/FZD9/GCLC/NPFF/P2RX7/SLMAP/GJA5	19
BP	GO:0032757	positive regulation of interleukin-8 production	19/4749	49/18670	0.02729	0.1501	0.1221	IL1B/TLR8/TIRAP/CLEC7A/LGALS9/TNF/HSPA1A/TLR4/SERPINE1/FFAR2/FCN1/CD74/TLR2/CD58/NOD2/DDIT3/PARK7/ADIPOQ/F2R	19
BP	GO:0051445	regulation of meiotic cell cycle	19/4749	49/18670	0.02729	0.1501	0.1221	LIF/ASPM/TTK/TRIP13/CDC20/CDC25A/PPP2R1A/FBXO43/UBE2B/CDC25C/MSX1/FBXO5/SIRT2/PRKACB/ANKRD31/INSR/PLCB1/CDC25B/DUSP1	19
BP	GO:1901214	regulation of neuron death	95/4749	313/18670	0.0273	0.1501	0.1221	EGR1/KIF14/TYRO3/NR4A3/CASP9/ADORA2A/NTRK2/IL10/FAIM2/NTRK1/EPHB1/GRN/CNTF/VSTM2L/MYBL2/MCL1/CDK5/GPNMB/STAMBP/ASCL1/TNF/CSF1/FOXB1/CD200/TLR4/BAX/MTOR/STAT3/SORL1/HMOX1/PARP2/ARRB1/CCL3/ATP13A2/CLU/UBB/AXL/TGFB3/PPT1/ATF4/AMBRA1/CCL2/NQO1/PAK3/MAP3K5/PINK1/CORO1A/DDIT4/ITGA1/PRKCI/ZNF746/MAP3K11/LRP1/GBA/DDIT3/TLR6/CHP1/PARK7/ELK1/JUN/TFAP2B/PPP5C/AGAP2/CTSZ/CEBPB/BCL2L1/MAP2K4/IL13/TRAF2/CD34/PRNP/TNFRSF1B/F2R/NAE1/TYROBP/C1QA/FZD9/GCLC/NUPR1/FGF8/NEFL/NTF3/FOS/ATM/ATG7/POU4F1/NMNAT1/ADNP/GATA3/CX3CR1/BAD/RRAS2/FYN/ILK/SIRT1	95
BP	GO:0017038	protein import	63/4749	199/18670	0.02791	0.1532	0.1247	TXNIP/CDKN1A/RBM22/PML/KPNA2/NUP98/RGPD2/TIMM17A/MMP12/LMNA/STAT3/CSE1L/ARHGEF5/TIMM10/CLU/FGF9/NUP153/PDCD5/TMCO6/RPL23/TIMM22/TIMM50/ROMO1/DRD1/NUP88/GRPEL1/NOLC1/RANBP6/FAM53B/CHP1/EFCAB7/KPNA3/PEX2/NFKBIA/CABP1/POM121C/ECT2/SNX33/ARNTL/NUP50/ZC3H12A/BAG3/FAM53A/PEX3/RAB23/PEX5/POM121L2/SNUPN/PAM16/NUP93/TOMM22/AGK/NUP35/CHCHD4/PEX13/TGFB1/NDUFA13/RGPD1/MAPK1/NUP62/TNPO1/TIMM9/PEX1	63
BP	GO:0061013	regulation of mRNA catabolic process	63/4749	199/18670	0.02791	0.1532	0.1247	TIRAP/YWHAZ/SERBP1/ZFP36/E2F1/HSPA1A/ZC3H12D/PLEKHN1/MTOR/PSMD8/HNRNPA0/TNRC6B/UBB/PSMD1/PSMD2/PSMF1/CIRBP/UPF1/RPS27A/ZFP36L2/PRKCA/ALKBH5/RBM46/UBA52/MEX3D/PSMD9/PSMA5/RBM23/FMR1/PSMB7/EXOSC2/PSMD5/ZC3H12A/VIM/PSME2/ELAVL1/CNOT7/CSDC2/YTHDF3/FASTKD3/METTL16/TNFSF13/SAMD4B/GIGYF2/PSMB5/RBM38/MAPKAPK2/ZC3HAV1/YBX1/ZFP36L1/PSMB4/PSMA3/TBRG4/AXIN2/PSMD10/PSMB1/PSMD7/PSMB3/PSMC5/TNPO1/KHSRP/EXOSC9/PSMD11	63
BP	GO:0046635	positive regulation of alpha-beta T cell activation	23/4749	62/18670	0.02796	0.1533	0.1247	EBI3/CD86/IL18/NLRP3/CD83/CD80/CBFB/TNFSF4/LGALS9/FOXP3/IL4R/CCR2/HLX/PNP/PTPRC/HLA-E/AP3D1/IL12RB1/CD3E/RIPK2/RARA/ZAP70/IL23A	23
BP	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	61/4749	192/18670	0.02806	0.1536	0.125	LIF/HBEGF/VEGFA/IL18/CSF2/IL21/ICAM1/NTRK2/NEDD9/CSF1R/CD80/TNFRSF18/CNTF/TNF/LRP8/LRRK1/PTPN1/MTOR/STAT3/PARP14/FCGR1A/SRC/SOCS3/ARHGEF2/HTR2A/CD74/UNC119/DOCK3/FLT3/PTK6/CCK/LRP4/PTPRC/VTN/OSM/CD44/PIBF1/LILRA5/LACRT/CD3E/IL13/IL20/GHRL/ADIPOQ/IL4/ARL2BP/PRNP/RIPK2/SEMA4D/FGF8/NCF1/NTF3/THBS4/TGFB1/ADNP/PDGFB/EHD4/FYN/DLG4/PAK2/IL23A	61
BP	GO:1901136	carbohydrate derivative catabolic process	61/4749	192/18670	0.02806	0.1536	0.125	SDC4/NAGA/DCTPP1/TYMP/NEU4/GLB1/HPSE/GPC1/APOBEC3H/PDE4A/GM2A/NEU1/ABCD1/MMP12/APOBEC3B/HYAL3/IDS/NUDT16/NUDT1/OGN/IDUA/PDE4D/CST3/PDE4B/SDC2/HPRT1/PNP/FBXO27/SDC1/OVGP1/PGLYRP3/FUCA2/GNPDA1/GBA/AICDA/CHP1/GPC2/ENPP4/CD44/EDEM2/DPYD/SAMHD1/GSK3A/ENTPD4/NUDT3/ADAMTS9/AMPD3/NEU3/NT5E/PDE7B/GALC/HEXB/GALT/GUSB/MANBA/FBXO44/NEIL1/OGG1/FUCA1/TGFB1/NAGK	61
BP	GO:0016079	synaptic vesicle exocytosis	40/4749	119/18670	0.02814	0.1538	0.1251	ADORA2A/RIMS3/CDK5/SYN1/NCS1/CHRNA5/STX11/BLOC1S6/P2RX1/SYT4/SNAP47/HTR2A/CAMK2A/SNAP29/PFN2/APBA2/STX1B/DVL1/SCRIB/STX19/DRD1/SNAP23/DTNBP1/WNT7A/PPFIA3/CNR1/FMR1/SYT11/ERC2/SNAPIN/NAPB/STX2/DOC2B/PRKCB/P2RY1/CACNB2/FBXL20/SV2A/P2RX7/TRIM9	40
BP	GO:0061572	actin filament bundle organization	51/4749	157/18670	0.02815	0.1538	0.1251	SDC4/FSCN1/NEDD9/SRF/MARCKS/RAC1/ZYX/NF2/FHOD1/MTOR/BAG4/SWAP70/SRC/ARHGEF5/TNFAIP1/CORO1B/ARRB1/PLS1/PTGER4/PDXP/TGFB3/PAK1/ADD3/PFN2/S1PR1/EZR/STMN1/CLASP2/CD47/AIF1/LIMCH1/ACTN4/S100A10/MKKS/ARAP1/LIMK1/SH3PXD2B/SHROOM1/RHOF/ALMS1/SFRP1/KCTD13/FAM171A1/TPM1/AIF1L/SORBS3/WASF2/ID1/CDC42/WAS/ADD2	51
BP	GO:1902275	regulation of chromatin organization	59/4749	185/18670	0.02817	0.1538	0.1251	TWIST1/LIF/IL1B/VEGFA/MKI67/BCL6/SPI1/PHF19/ZNHIT1/SETD7/SIRT6/SKI/UBE2B/SPTY2D1/FOXP3/SMARCB1/LMNA/NAP1L2/CCNB1/IWS1/ARRB1/CDC45/MORC2/KAT2A/UBE2N/BCOR/RNF40/ZNF304/PINK1/EED/BRD4/SUPT6H/MUC1/AICDA/FMR1/ATAD2/MAP1S/CHEK1/C6orf89/MLLT6/PADI2/CAMK2D/TAF7/KDM5A/DMRTC2/TADA2A/SPHK2/CTBP1/ATM/KDM4C/TGFB1/ZNF451/PPHLN1/ASF1A/SETDB1/PHF8/GATA3/USP17L2/SIRT1	59
BP	GO:0070646	protein modification by small protein removal	91/4749	299/18670	0.02822	0.154	0.1253	CDK1/NLRP3/CDC20/CCNA2/CLSPN/SENP7/USP35/TFPT/CDC25A/STAMBP/DDB2/USP53/USP9X/SMAD7/ASXL2/USP36/OTUB2/PSMD8/VCP/ENY2/STAM/USP19/UBB/PSMD1/PSMD2/BAP1/KAT2A/MBD6/ACTL6A/PSMF1/MBD5/UBXN1/RPS27A/CYLD/RAD23B/SUPT3H/UBA52/USP40/USP54/TAF9B/RCE1/PSMD9/TANK/ASXL1/PSMA5/OTUD7B/HGS/TAF10/MDM4/BRCC3/PARK7/PSMB7/TAB1/USP44/NFKBIA/MCRS1/RAD23A/PSMD5/USP5/UCHL5/ZC3H12A/UCHL3/SIAH2/BIRC3/PSME2/TNIP3/SMAD1/TRAF2/PSMB5/ESR1/USP45/PSMB4/TRAF6/PSMA3/APC/SENP6/COPS7A/JOSD1/WDR48/PSMD10/PSMB1/PSMD7/PSMB3/SPATA2/UCHL1/PSMC5/GATA3/USP17L2/BARD1/PSMD11/ACTB	91
BP	GO:0050730	regulation of peptidyl-tyrosine phosphorylation	79/4749	256/18670	0.02834	0.1545	0.1257	LIF/HBEGF/VEGFA/IL18/CSF2/IL21/ICAM1/MVP/NTRK2/NEDD9/CSF1R/PDGFA/CD80/PTPN6/TNFRSF18/CNTF/NF2/PPP2R1A/TNF/LRP8/LRRK1/PTPN1/MTOR/STAT3/PARP14/FCGR1A/SRC/SOCS3/FGFR1OP/ARHGEF2/SAMSN1/HTR2A/CD74/UNC119/DOCK3/FLT3/PTK6/CCK/PDCL3/LRP4/PTPRC/SH3BP5L/DUSP22/VTN/PPP2CA/THY1/OSM/GGNBP2/CD44/PIBF1/PRKCE/IL7/LILRA5/LACRT/CD3E/CNOT7/IL13/IL20/SFRP1/GHRL/ADIPOQ/IL4/ARL2BP/PRNP/RIPK2/SEMA4D/FGF8/NCF1/NTF3/THBS4/TGFB1/ADNP/PDGFB/SHC1/EHD4/FYN/DLG4/PAK2/IL23A	79
BP	GO:0060443	mammary gland morphogenesis	18/4749	46/18670	0.02838	0.1546	0.1258	VDR/CSF1R/PTCH1/PML/CSF1/BAX/CAPN1/SRC/ETV5/KDM5B/SCRIB/ARG1/LRP5L/DDR1/BTRC/ESR1/LRP6/TGFB1	18
BP	GO:0032024	positive regulation of insulin secretion	26/4749	72/18670	0.02881	0.1568	0.1276	RAC1/BLK/ABAT/ARRB1/C2CD2L/SRI/CASR/TCF7L2/TRPM4/NADK/OXCT1/PFKFB2/PSMD9/LRP1/SIRT3/PRKCE/GLUD1/GHRL/SERP1/DOC2B/PPARD/FFAR1/PDX1/GIPR/SYBU/BAD	26
BP	GO:0034502	protein localization to chromosome	29/4749	82/18670	0.02902	0.1578	0.1284	AURKB/CENPA/CDCA5/TTK/CDK1/CDT1/ESCO2/BRCA2/PLK1/NDC80/BOD1/CCT5/TERF1/CARM1/EZH2/TNKS2/ACD/GNL3/POT1/WRAP53/ESR1/ATR/CHAMP1/TINF2/TRAPPC12/PPHLN1/LRWD1/TERF2/CCT3	29
BP	GO:0034620	cellular response to unfolded protein	46/4749	140/18670	0.02939	0.1595	0.1298	HSPA2/ATP6V0D1/ATF3/HSPA5/CREB3L2/SERP2/HSPA1A/DERL1/BAX/TPP1/PTPN1/ZBTB17/LMNA/SYVN1/HSPA9/VCP/HERPUD1/ATF4/ASNS/CTH/CCL2/EXTL2/PARP16/BAK1/DDIT3/CREBRF/BAG3/FICD/GSK3A/HSPA6/KLHDC3/YIF1A/DDX11/EIF2AK3/ERN1/SERP1/CANX/HSPA1L/RNF121/HSPA14/MBTPS2/PPP1R15A/HERPUD2/TMEM33/CCND1/SHC1	46
BP	GO:0035023	regulation of Rho protein signal transduction	46/4749	140/18670	0.02939	0.1595	0.1298	TIAM2/PLEKHG2/ARHGEF39/ITGA3/KANK2/RAC1/ARHGEF40/BCL6/ARHGEF18/FGD2/CDC42SE1/MCF2L2/ARHGEF12/ARHGEF5/TNFAIP1/TIAM1/ARHGEF2/F2RL2/ARRB1/ARHGAP35/RASGRF2/GPR35/PREX1/PLEKHG1/EPS8L2/VAV2/STMN1/PLEKHG7/ABCA1/FLOT1/P2RY10/CCDC125/ECT2/MYO9B/KCTD13/F2R/OBSCN/CDC42SE2/ARHGDIA/AKAP13/BCR/MCF2L/NET1/RTN4R/SPATA13/ARHGEF26	46
BP	GO:0030866	cortical actin cytoskeleton organization	17/4749	43/18670	0.02944	0.1596	0.1298	ANLN/KIF23/CIT/RACGAP1/CDK5/RTKN/TNF/WIPF2/PLS1/RAB13/FMNL1/EZR/ECT2/EPB41L2/EPB41/ARF6/WAS	17
BP	GO:0060612	adipose tissue development	17/4749	43/18670	0.02944	0.1596	0.1298	CSF1/ARRDC3/SORL1/UBB/ARID5B/SLC25A25/RORC/CASR/TRPM4/OXCT1/SOX8/SH3PXD2B/LRP5L/GHRL/DGAT2/PPARD/SIRT1	17
BP	GO:0090501	RNA phosphodiester bond hydrolysis	50/4749	154/18670	0.02976	0.16	0.1302	EXO1/HELZ2/FEN1/TSEN2/NUDT16/XRN2/USB1/RNASE8/TSEN15/DCPS/ISG20/NOL9/POP5/DIS3L2/ERI3/PAN3/RNASEH2A/TSEN34/ELAC1/POLR2I/YBEY/NOP14/EXOSC2/ANGEL1/RNASE6/UTP20/TSNAX/ZC3H12A/BOP1/UTP23/SAMHD1/ZNRD1/CNOT7/PPP1R8/ABT1/ERN1/ENDOV/CPSF1/SMG6/TUT1/DICER1/CPSF6/RPP30/RCL1/NCBP2/DIS3L/CSTF3/EXOSC9/PIWIL4/TSN	50
BP	GO:0002220	innate immune response activating cell surface receptor signaling pathway	39/4749	116/18670	0.02978	0.16	0.1302	RELB/CLEC10A/LILRA2/CARD9/FFAR2/FCN1/SRC/PSMD8/PSMD1/PSMD2/PAK1/PSMF1/PAK3/MUC1/PSMD9/PSMA5/CLEC4D/PSMB7/ICAM2/FBXW11/TAB1/PSMD5/PSME2/BTRC/CARD11/PSMB5/PRKACB/PSMB4/TRAF6/PSMA3/PSMD10/PSMB1/PSMD7/PSMB3/KLRK1/PSMC5/FYN/PAK2/PSMD11	39
BP	GO:2000027	regulation of animal organ morphogenesis	78/4749	253/18670	0.02982	0.16	0.1302	VDR/TWIST1/LIF/SAPCD2/VEGFA/NOTCH1/SULF2/PDGFA/RAC1/VANGL1/CNTF/CEACAM1/TNF/CSF1/BAX/MSX1/PIM1/RNF207/ETV5/NKD1/TIAM1/CTHRC1/PSMD8/CFLAR/TUG1/DVL3/PSMD1/PSMD2/FZD6/PTK7/RBPJ/PSMF1/BCOR/RUNX2/JAG1/HOXB7/SMURF1/CARM1/AMTN/DVL1/PSMD9/AP2S1/PSMA5/RXRA/WNT7A/SOX8/BASP1/PSMB7/PSMD5/CITED2/PSME2/SFRP1/RSPO3/TNFRSF11B/PSMB5/CD34/ESR1/POR/MLLT3/HOXA11/PSMB4/BMP10/FGF8/PSMA3/STAT1/MED12/PARD6A/FZD5/PSMD10/TGFB1/CDC42/PSMB1/PSMD7/PSMB3/AMELX/PSMC5/GATA3/PSMD11	78
BP	GO:0002295	T-helper cell lineage commitment	8/4749	16/18670	0.02992	0.16	0.1302	BATF/IRF4/MTOR/STAT3/LY9/IL12RB1/ZFPM1/IL23A	8
BP	GO:0010934	macrophage cytokine production	8/4749	16/18670	0.02992	0.16	0.1302	SEMA7A/TLR4/HLA-G/TGFB3/CD74/IRAK3/TGFB1/SIRT1	8
BP	GO:0030397	membrane disassembly	8/4749	16/18670	0.02992	0.16	0.1302	CDK1/CCNB2/PLK1/CCNB1/PRKCA/PRKCB/NEK9/LPIN1	8
BP	GO:0030889	negative regulation of B cell proliferation	8/4749	16/18670	0.02992	0.16	0.1302	IL10/TNFRSF21/CTLA4/BTK/TNFRSF13B/MNDA/TYROBP/ATM	8
BP	GO:0035970	peptidyl-threonine dephosphorylation	8/4749	16/18670	0.02992	0.16	0.1302	DUSP10/DUSP4/DUSP5/PPP2CA/PPP5C/PPM1G/DUSP18/DUSP1	8
BP	GO:0044794	positive regulation by host of viral process	8/4749	16/18670	0.02992	0.16	0.1302	CSF1R/ANXA2P2/SMC3/ANXA2/TBC1D20/CFL1/STOM/NUCKS1	8
BP	GO:0045623	negative regulation of T-helper cell differentiation	8/4749	16/18670	0.02992	0.16	0.1302	BCL6/TNFSF4/FOXP3/IL4R/SMAD7/HLX/ZC3H12A/JAK3	8
BP	GO:0046519	sphingoid metabolic process	8/4749	16/18670	0.02992	0.16	0.1302	KDSR/SGPP1/GBA/ACER1/ACER2/ASAH2/ASAH2B/SPHK2	8
BP	GO:0051081	nuclear envelope disassembly	8/4749	16/18670	0.02992	0.16	0.1302	CDK1/CCNB2/PLK1/CCNB1/PRKCA/PRKCB/NEK9/LPIN1	8
BP	GO:0051503	adenine nucleotide transport	8/4749	16/18670	0.02992	0.16	0.1302	SLC25A23/ABCD1/SLC25A25/SLC35B2/SLC25A5/SLC33A1/SLC25A42/SLC25A4	8
BP	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade	8/4749	16/18670	0.02992	0.16	0.1302	CHERP/TNF/SPPL3/PTBP1/LMCD1/C10orf71/CAMTA1/LACRT	8
BP	GO:0106058	positive regulation of calcineurin-mediated signaling	8/4749	16/18670	0.02992	0.16	0.1302	CHERP/TNF/SPPL3/PTBP1/LMCD1/C10orf71/CAMTA1/LACRT	8
BP	GO:1903541	regulation of exosomal secretion	8/4749	16/18670	0.02992	0.16	0.1302	SDC4/SNF8/SDCBP/ATP13A2/STAM/SDC1/HGS/CHMP2A	8
BP	GO:0070482	response to oxygen levels	117/4749	394/18670	0.02995	0.16	0.1302	EGR1/TWIST1/VEGFA/NOTCH1/CDKN1A/PPARG/ITGA2/ICAM1/SRF/BNIP3L/CCNA2/LDHA/ATP6V0D1/PTGIS/ENO1/PML/EIF4EBP1/CBFA2T3/SLC2A8/E2F1/HK2/CYBB/NOL3/PLEKHN1/PLAU/PMAIP1/MTOR/LMNA/PLAT/CCNB1/SRC/HMOX1/PKM/ABAT/LIMD1/PSMD8/CFLAR/PAM/USP19/UBB/PSMD1/TGFB3/PSMD2/PAK1/RBPJ/ATF4/SLC2A4/PSMF1/RPS27A/FOXO1/ATP1B1/CASR/KCNMB1/FAS/PICK1/PINK1/NAMPT/NDRG1/ALKBH5/DDIT4/ATP6V1A/ACTN4/UBA52/TLR2/PSMD9/IRAK1/PSMA5/VASN/MDM4/LTA/PSMB7/ERCC2/HIF3A/PRKCE/AK4/EPAS1/PSMD5/CITED2/CYBA/ADAM15/PSME2/XRCC1/ATP6V1G1/SFRP1/ADM/SIRT2/ALDH3A1/ADIPOQ/PSMB5/CD34/HMOX2/ZFP36L1/CPEB1/PSMB4/MALAT1/PSMA3/HIF1AN/BACH1/ATM/PPARD/ARNT2/CLCA1/PSMD10/ATG7/TGFB1/PSMB1/PSMD7/PSMB3/CCDC115/KCNK2/PSMC5/VEGFC/BAD/MGARP/FUNDC1/PSMD11/SIRT1	117
BP	GO:0048872	homeostasis of number of cells	76/4749	246/18670	0.03022	0.1613	0.1313	SKIL/VEGFA/NOTCH1/KLF2/SH2B2/RASSF2/SRF/ISG15/BCL6/SPI1/DYRK3/SFXN1/CCNB2/LGALS9/THRA/HMGB1/CSF1/ZFP36/HSPA1A/IL2RA/AKT3/BAX/PMAIP1/FOXP3/STAT3/RIPK3/CCR2/HMOX1/CCR4/MERTK/HSPA9/SIT1/RPS6/PDE4B/AXL/CD74/BAP1/FLT3/PPP2R3C/DNAJA3/RPS19/CYLD/CORO1A/EZH2/LAT/FANCC/BAK1/ASXL1/MAEA/TNFRSF13B/ERCC2/EPAS1/IL7R/IL7/CARD11/AMPD3/P4HTM/GIGYF2/F2R/TSC22D3/ZFP36L1/BCR/STAT1/LIPA/ARID4A/WDR48/TGFB1/JAK3/MIR17HG/ZFPM1/SLC40A1/LDB1/GATA3/P2RX7/PRDX1/RAC3	76
BP	GO:0071621	granulocyte chemotaxis	41/4749	123/18670	0.03033	0.1618	0.1316	CXCL13/IL1B/CCL20/CCL3L3/RAC1/IL1RN/CSF3R/CCL22/TIRAP/DAPK2/LGALS3/CSF1/CXCL10/PDE4D/CCL3/PDE4B/CD74/CCL2/PREX1/CCL17/ITGA1/CCL18/CXCL9/CXCL2/CXCL3/GBF1/C3AR1/IL17RC/RAC2/RARRES2/S100A8/CKLF/IL36A/C1QBP/CCL23/CCL7/PPBP/THBS4/CCL15/IL37/IL23A	41
BP	GO:0031110	regulation of microtubule polymerization or depolymerization	28/4749	79/18670	0.03066	0.1634	0.1329	SKA1/FES/RAC1/SKA3/HSPA1A/CKAP2/RANGRF/PSRC1/MAPRE2/NUMA1/ARHGEF2/CLIP3/PAK1/RPS3/STMN3/TERF1/FGF13/STMN1/CLASP2/MID1/TUBB4A/MAP1S/TRIM54/MAP1A/APC/ARL2/SLAIN2/CDH5	28
BP	GO:0042136	neurotransmitter biosynthetic process	36/4749	106/18670	0.03079	0.1636	0.1331	IL1B/ICAM1/KLF2/IL10/ACP5/KLF4/RAC1/PTGIS/SIRPA/CLEC7A/TNF/TLR4/DDAH2/MTOR/TSPO/ABAT/MOXD1/CLU/PKD2/NQO1/CD47/AIF1/GCHFR/ATP2B4/TLR6/DPYD/ZC3H12A/TPH1/CD34/HBB/INSR/ALDH9A1/SPR/KLRK1/CX3CR1/KHSRP	36
BP	GO:0031295	T cell costimulation	21/4749	56/18670	0.03079	0.1636	0.1331	CD86/CD80/RAC1/PDCD1/PTPN6/TNFSF4/CTLA4/SRC/PAK1/GRAP2/EFNB1/LGALS1/PAK3/PDCD1LG2/CD3E/CARD11/CDC42/HHLA2/KLRK1/FYN/PAK2	21
BP	GO:0065002	intracellular protein transmembrane transport	21/4749	56/18670	0.03079	0.1636	0.1331	HSPA5/TIMM17A/TIMM10/SEC61A2/TIMM22/TIMM50/ROMO1/TRAM2/SEC61B/GRPEL1/PEX2/PEX5/ZFAND2B/PAM16/BCR/AGK/CHCHD4/PEX13/NDUFA13/TIMM9/PEX1	21
BP	GO:0098586	cellular response to virus	21/4749	56/18670	0.03079	0.1636	0.1331	MAPK11/IRF7/LGALS9/MMP12/IFI6/SEC14L1/NPLOC4/FMR1/GBF1/LGALS8/BCL2L1/IRF3/ZC3H12A/BIRC3/C1QBP/TSPAN6/ANKRD17/ZCCHC3/USP17L2/BAD/TRIM15	21
BP	GO:0007099	centriole replication	15/4749	37/18670	0.0314	0.1665	0.1355	STIL/WDR62/PLK4/PLK2/CENPJ/CDK2/KAT2A/MDM1/CEP152/C10orf90/ALMS1/CETN2/CHMP2A/CEP72/NUP62	15
BP	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	15/4749	37/18670	0.0314	0.1665	0.1355	NEDD9/RAC1/MYADM/DOCK1/LIMS1/DOCK5/PREX1/TRIOBP/S100A10/UNC13D/CRK/C1QBP/CDC42/HAS2/RAC3	15
BP	GO:0001573	ganglioside metabolic process	9/4749	19/18670	0.03192	0.1672	0.136	NEU4/GM2A/NEU1/ITGB8/B4GALT5/NEU3/HEXB/ST8SIA3/ST6GALNAC6	9
BP	GO:0002363	alpha-beta T cell lineage commitment	9/4749	19/18670	0.03192	0.1672	0.136	BATF/IRF4/MTOR/FOXP3/STAT3/LY9/IL12RB1/ZFPM1/IL23A	9
BP	GO:0002544	chronic inflammatory response	9/4749	19/18670	0.03192	0.1672	0.136	CXCL13/IL10/TNF/FOXP3/LTA/UNC13D/IDO1/S100A8/VNN1	9
BP	GO:0002710	negative regulation of T cell mediated immunity	9/4749	19/18670	0.03192	0.1672	0.136	CEACAM1/FOXP3/SMAD7/HLA-G/CLEC4G/PTPRC/DUSP22/ARG1/IL7R	9
BP	GO:0009148	pyrimidine nucleoside triphosphate biosynthetic process	9/4749	19/18670	0.03192	0.1672	0.136	TYMS/CMPK2/DTYMK/NME4/NME3/CTPS2/UCK2/NME9/NME2	9
BP	GO:0019184	nonribosomal peptide biosynthetic process	9/4749	19/18670	0.03192	0.1672	0.136	CHAC1/CHAC2/GGT1/OPLAH/BDH2/MGST2/GCLC/GGT7/GSS	9
BP	GO:0032288	myelin assembly	9/4749	19/18670	0.03192	0.1672	0.136	GPC1/CD9/PIKFYVE/MPP5/TLR2/ERCC2/PMP22/DICER1/ILK	9
BP	GO:0046112	nucleobase biosynthetic process	9/4749	19/18670	0.03192	0.1672	0.136	MTHFD1L/DHODH/MTOR/HPRT1/MTHFD1/APRT/CMPK1/CTPS2/PRPS1	9
BP	GO:0046597	negative regulation of viral entry into host cell	9/4749	19/18670	0.03192	0.1672	0.136	GSN/TRIM25/TRIM26/FCN1/IFITM2/IFITM3/IFITM1/MID2/TRIM5	9
BP	GO:0048490	anterograde synaptic vesicle transport	9/4749	19/18670	0.03192	0.1672	0.136	BLOC1S6/BLOC1S1/CNIH2/BLOC1S4/AP3D1/DTNBP1/AP3M2/SNAPIN/AP3B2	9
BP	GO:0071243	cellular response to arsenic-containing substance	9/4749	19/18670	0.03192	0.1672	0.136	PPIF/ATF3/HMOX1/VCP/ATF4/GSTO1/ZC3H12A/ZFAND2A/ZFAND1	9
BP	GO:0071800	podosome assembly	9/4749	19/18670	0.03192	0.1672	0.136	FSCN1/CSF2/HCK/TNF/GSN/SRC/ARHGEF5/ARHGEF2/SH3PXD2B	9
BP	GO:0099514	synaptic vesicle cytoskeletal transport	9/4749	19/18670	0.03192	0.1672	0.136	BLOC1S6/BLOC1S1/CNIH2/BLOC1S4/AP3D1/DTNBP1/AP3M2/SNAPIN/AP3B2	9
BP	GO:0099517	synaptic vesicle transport along microtubule	9/4749	19/18670	0.03192	0.1672	0.136	BLOC1S6/BLOC1S1/CNIH2/BLOC1S4/AP3D1/DTNBP1/AP3M2/SNAPIN/AP3B2	9
BP	GO:1990182	exosomal secretion	9/4749	19/18670	0.03192	0.1672	0.136	SDC4/SNF8/SDCBP/ATP13A2/STAM/SDC1/HGS/RAB27A/CHMP2A	9
BP	GO:1901607	alpha-amino acid biosynthetic process	24/4749	66/18670	0.032	0.1675	0.1362	BCAT1/SERINC3/GAMT/GGT1/GLS2/ASNS/CTH/MRI1/MTHFD1/BHMT/ATP2B4/NAGS/PARK7/SEPHS1/MTRR/MTAP/PSPH/GLUD1/ENOPH1/AASDHPPT/MTR/PLOD3/ASNSD1/BHMT2	24
BP	GO:0022612	gland morphogenesis	40/4749	120/18670	0.03211	0.1678	0.1365	VDR/NOTCH1/SULF2/CSF1R/PDGFA/CYP7B1/CEACAM1/TP63/PTCH1/PML/TNF/CSF1/CRIP1/BAX/CAPN1/SRC/ETV5/TGM2/CFLAR/PLXNA1/TGFB3/KDM5B/PLXND1/SCRIB/FEM1B/ARG1/RXRA/GDF7/CEBPB/LRP5L/DDR1/BTRC/SFRP1/ESR1/LRP6/FGF8/EDAR/TGFB1/LAMA5/ESRP2	40
BP	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	30/4749	86/18670	0.0322	0.1678	0.1365	KIF2C/KIF4A/KIF15/KIF23/SURF4/KIF1C/RACGAP1/KIF18A/KIF11/KLC1/CENPE/KDELR2/KIF4B/HTT/COG7/TMED3/PICK1/COPE/TMED9/TMEM115/KIF3C/GBF1/TMED10/LMAN2/UVRAG/ARF4/COG3/RAB1A/COPG2/RAB1B	30
BP	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	30/4749	86/18670	0.0322	0.1678	0.1365	PPARG/NLRP3/CASP9/CTSH/HIP1/PML/TNF/BAX/PMAIP1/DAP/P2RX1/VCP/BCL2L13/HIP1R/CCK/FAS/BID/TNFRSF10B/KHDC1/BAK1/CASP8AP2/ACER2/TRAF2/EIF2AK3/S100A8/F3/F2R/TNFSF10/CARD8/BAD	30
BP	GO:0070542	response to fatty acid	30/4749	86/18670	0.0322	0.1678	0.1365	PPARG/TNFSF4/E2F1/LDLR/FFAR2/CCNB1/SRC/SCD/GLDC/PTGER4/HMGCL/ADCY6/ACSL1/FFAR3/TLR2/PPP5C/PRKCE/PTGER2/ZC3H12A/SFRP1/ADIPOQ/CPT1A/DGAT2/AANAT/FFAR1/PTAFR/PDX1/GIPR/BAD/NME2	30
BP	GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator	14/4749	34/18670	0.03223	0.1678	0.1365	TWIST1/SPRED2/DYRK3/ZNF385A/PMAIP1/MSX1/SNAI1/RPL26/CD74/CD44/ATR/ATM/PSMD10/SIRT1	14
BP	GO:0045738	negative regulation of DNA repair	14/4749	34/18670	0.03223	0.1678	0.1365	TWIST1/PARPBP/RMI2/TP53BP1/POLQ/MAGEF1/RPS3/TFIP11/RECQL5/AUNIP/MAD2L2/HELB/OGG1/TERF2	14
BP	GO:0035065	regulation of histone acetylation	20/4749	53/18670	0.03228	0.1678	0.1365	TWIST1/LIF/IL1B/SPI1/FOXP3/SMARCB1/NAP1L2/IWS1/ARRB1/KAT2A/MUC1/CHEK1/TAF7/TADA2A/SPHK2/CTBP1/TGFB1/ZNF451/GATA3/SIRT1	20
BP	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	20/4749	53/18670	0.03228	0.1678	0.1365	MVP/PTPN6/NF2/PPP2R1A/LRRK1/PARP14/SOCS3/FGFR1OP/SAMSN1/PTK6/PTPRC/SH3BP5L/DUSP22/PPP2CA/THY1/GGNBP2/PIBF1/SFRP1/SEMA4D/NTF3	20
BP	GO:1901264	carbohydrate derivative transport	27/4749	76/18670	0.03238	0.1682	0.1369	SLC29A2/SLC35A2/ABCG1/SLC35E4/MFSD2A/SLC29A1/SLC25A23/ABCD1/SLC35B1/SLC25A25/SLC35D2/SLC35D1/SLC35B2/SLC35E3/SLC25A5/PLEKHA8/PRKCE/SLC35C1/CYBA/SLC29A3/SLC33A1/GUK1/SLC25A42/SLC35B4/SLC25A4/SLC28A1/RALBP1	27
BP	GO:0002675	positive regulation of acute inflammatory response	13/4749	31/18670	0.03289	0.1697	0.1381	IL1B/C2CD4B/TNF/FFAR2/BTK/FFAR3/HLA-E/OSM/CNR1/PARK7/KLKB1/TNFSF11/C2CD4A	13
BP	GO:0007143	female meiotic nuclear division	13/4749	31/18670	0.03289	0.1697	0.1381	TTK/TOP2A/AURKA/TRIP13/PPP2R1A/PLK1/FBXO5/UBB/NCAPH/NCAPH2/ATM/MLH3/CDC25B	13
BP	GO:0043457	regulation of cellular respiration	13/4749	31/18670	0.03289	0.1697	0.1381	CDK1/TREX1/PRELID1/CBFA2T3/SLC25A23/CCNB1/VCP/NOA1/PRDM16/PINK1/PARK7/IL4/ISCU	13
BP	GO:1902186	regulation of viral release from host cell	13/4749	31/18670	0.03289	0.1697	0.1381	PML/SMC3/CHMP2B/TRIM25/TRIM26/TRIM62/TRIM13/MID2/CHMP2A/TRIM35/CHMP3/TRIM15/TRIM5	13
BP	GO:1902253	regulation of intrinsic apoptotic signaling pathway by p53 class mediator	13/4749	31/18670	0.03289	0.1697	0.1381	ZNF385A/RRM2B/MSX1/RPL26/UBB/CD74/TAF9B/MUC1/BDKRB2/BCL2L12/CD44/RPL11/SIRT1	13
BP	GO:0032273	positive regulation of protein polymerization	44/4749	134/18670	0.0329	0.1697	0.1381	CDC42EP4/ICAM1/FES/HCK/RAC1/TTBK1/CYFIP1/SNX9/GSN/HSPA1A/CTTN/MTOR/BAG4/PSRC1/CDC42EP1/TPPP3/TPPP/TENM1/NUMA1/CORO1B/WHAMMP3/PAK1/PFN2/RPS3/HIP1R/ARPC1B/TERF1/PICK1/PINK1/CORO1A/VASP/ARPC5/PRKCE/ACTR3B/FER/ARF6/ARL2/WHAMM/AP1AR/SLAIN2/C15orf62/WAS/FMN1/RAC3	44
BP	GO:0000469	cleavage involved in rRNA processing	10/4749	22/18670	0.03299	0.1697	0.1381	NOL9/ERI3/NOP14/EXOSC2/UTP20/BOP1/UTP23/ABT1/RCL1/EXOSC9	10
BP	GO:0009220	pyrimidine ribonucleotide biosynthetic process	10/4749	22/18670	0.03299	0.1697	0.1381	DHODH/AK5/NME4/UPRT/NME3/CMPK1/CTPS2/UCK2/NME9/NME2	10
BP	GO:0010155	regulation of proton transport	10/4749	22/18670	0.03299	0.1697	0.1381	TWIST1/PPIF/COX17/DNAJC30/ACTN4/CHP1/PARK7/IL13/TESC/SPHK2	10
BP	GO:0046599	regulation of centriole replication	10/4749	22/18670	0.03299	0.1697	0.1381	STIL/PLK4/PLK2/CENPJ/KAT2A/MDM1/C10orf90/ALMS1/CHMP2A/NUP62	10
BP	GO:1901984	negative regulation of protein acetylation	10/4749	22/18670	0.03299	0.1697	0.1381	TWIST1/SPI1/FOXP3/PARK7/TAF7/CTBP1/ZNF451/HINT2/MAGEA2B/SIRT1	10
BP	GO:2000773	negative regulation of cellular senescence	10/4749	22/18670	0.03299	0.1697	0.1381	TWIST1/BCL6/PLK2/AKT3/FBXO5/NAMPT/BCL2L12/MAP3K3/TERF2/SIRT1	10
BP	GO:0002792	negative regulation of peptide secretion	48/4749	148/18670	0.03328	0.1705	0.1387	IL1B/NLRP3/IL10/TLR8/PIM3/RAB11FIP1/PML/TNF/TNFRSF4/CD200/BTN2A2/TNFRSF21/FOXP3/ADTRP/IL1R2/RSAD2/FRMD4A/SYT4/PTGER4/ENY2/CD74/ENHO/EZR/ANXA5/PSMD9/IL27RA/C1QTNF3/TLR6/RAB11FIP3/ACVR1C/ANXA4/DEFB114/SYT11/SRGN/ZC3H12A/RABGEF1/LILRA5/SFRP1/GHRL/CD34/RAB11FIP5/F2R/HDAC9/CARD8/PFKL/NPFF/NDUFAF2/LRRC32	48
BP	GO:0051984	positive regulation of chromosome segregation	12/4749	28/18670	0.0333	0.1705	0.1387	ESPL1/CDT1/DLGAP5/SFPQ/CDC6/FEN1/CCNB1/NUMA1/ANAPC11/DDX11/SIRT2/SMC5	12
BP	GO:0070198	protein localization to chromosome, telomeric region	12/4749	28/18670	0.0333	0.1705	0.1387	BRCA2/CCT5/TERF1/TNKS2/ACD/GNL3/POT1/WRAP53/ATR/TINF2/TERF2/CCT3	12
BP	GO:0006664	glycolipid metabolic process	37/4749	110/18670	0.03337	0.1705	0.1387	B3GNT5/NAGA/CTSA/NEU4/GLB1/GBGT1/GM2A/NEU1/BAX/ITGB8/FA2H/PIGK/PIGH/DPM2/ST8SIA1/GAL3ST2/SUMF1/ST6GALNAC4/PIGQ/PIGO/GBA/PIGC/PIGW/B4GALT5/NEU3/GALC/HEXB/GAL3ST4/PIGM/SUMF2/PIGA/ST8SIA3/FUCA1/ALDH5A1/ST6GALNAC6/PIGG/PIGT	37
BP	GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway	11/4749	25/18670	0.03338	0.1705	0.1387	TRIB1/LILRA2/CD180/SIGIRR/PRKCA/DEFB114/NFKBIL1/LACRT/TRAF6/CARD8/TRIM5	11
BP	GO:0032438	melanosome organization	11/4749	25/18670	0.03338	0.1705	0.1387	BLOC1S6/RAB32/BLOC1S1/BLOC1S4/HPS4/AP3D1/DTNBP1/ASIP/RAB38/SNAPIN/TYRP1	11
BP	GO:0045332	phospholipid translocation	11/4749	25/18670	0.03338	0.1705	0.1387	ABCC1/ATP11A/ATP8B4/ABCA1/KCNN4/TMEM30A/ABCB4/ATP10A/ATP8B3/ATP10D/ATP11C	11
BP	GO:0070129	regulation of mitochondrial translation	11/4749	25/18670	0.03338	0.1705	0.1387	NSUN4/FASTKD2/COA3/TRUB2/MTG1/FASTKD3/LRPPRC/TRMT10C/C1QBP/NGRN/MALSU1	11
BP	GO:1903306	negative regulation of regulated secretory pathway	11/4749	25/18670	0.03338	0.1705	0.1387	NOTCH1/CEACAM1/LGALS9/CCR2/HMOX1/SYT4/GNAI2/FMR1/RABGEF1/BCR/TRIM9	11
BP	GO:0000045	autophagosome assembly	32/4749	93/18670	0.03347	0.1706	0.1388	TP53INP2/MTMR3/MAP1LC3A/ATG9A/AMBRA1/PIKFYVE/SMURF1/PINK1/ULK1/TP53INP1/STX12/ATG2B/KIAA1324/BAG3/UBQLN2/NPRL3/RAB23/PIK3C3/ATG4B/NSFL1C/TMEM41B/LRSAM1/WDR45/NUPR1/PIP4K2A/RAB1A/RALB/PIP4K2B/PHF23/ATG7/RAB1B/NPRL2	32
BP	GO:0006476	protein deacetylation	32/4749	93/18670	0.03347	0.1706	0.1388	VEGFA/RCOR1/BCL6/SPRED2/SFPQ/ZNHIT1/SIRT6/SKI/FOXP3/MORF4L2/PER2/ELK4/PINK1/SIRT3/MIER2/C6orf89/SAP30L/BEX4/SIRT2/CAMK2D/KDM5A/BAZ2A/SPHK2/MTA1/CTBP1/HDAC9/MTA3/SIRT7/TGFB1/HDAC10/USP17L2/SIRT1	32
BP	GO:0046634	regulation of alpha-beta T cell activation	32/4749	93/18670	0.03347	0.1706	0.1388	EBI3/CD86/IL18/NLRP3/ADORA2A/CD83/CD80/IRF4/BCL6/CBFB/TNFSF4/LGALS9/PRDM1/HMGB1/FOXP3/IL4R/SMAD7/CCR2/HLX/PNP/PTPRC/HLA-E/AP3D1/IL12RB1/ZC3H12A/CD3E/RIPK2/JAK3/RARA/ZAP70/GATA3/IL23A	32
BP	GO:0010171	body morphogenesis	19/4749	50/18670	0.0338	0.172	0.1399	CSRNP1/SKI/ASPH/PLEKHA1/MSX1/GNAS/GREM2/TGFB3/ARID5B/SSBP3/CLASP2/IFT122/MAB21L2/ZNF281/PHLDB1/DLX5/LRP6/TGFB1/ANKRD11	19
BP	GO:0033059	cellular pigmentation	19/4749	50/18670	0.0338	0.172	0.1399	MYO7A/BBS2/MYO5A/BLOC1S6/RAB32/BLOC1S1/VPS33B/BLOC1S4/HPS4/AP3D1/MKKS/DTNBP1/RAB27A/ASIP/RAB38/SHROOM3/SNAPIN/RAB1A/TYRP1	19
BP	GO:0060218	hematopoietic stem cell differentiation	29/4749	83/18670	0.03405	0.1731	0.1409	TP73/BATF/SRF/CBFB/HSPA9/PSMD8/PSMD1/PSMD2/PSMF1/PSMD9/PSMA5/OSM/PSMB7/ERCC2/PSMD5/YAP1/PSME2/SFRP1/PSMB5/PSMB4/PSMA3/PSMD10/PSMB1/PSMD7/PSMB3/PSMC5/LDB1/GATA3/PSMD11	29
BP	GO:0001736	establishment of planar polarity	41/4749	124/18670	0.03447	0.175	0.1423	SAPCD2/RAC1/VANGL1/TP63/NKD1/TIAM1/CTHRC1/PSMD8/DVL3/PSMD1/PSMD2/FZD6/PTK7/PSMF1/SMURF1/DVL1/PSMD9/AP2S1/PSMA5/WNT7A/PSMB7/PSMD5/WDR1/PSME2/BRSK2/SFRP1/RSPO3/PSMB5/MLLT3/PSMB4/PSMA3/MED12/PARD6A/FZD5/PSMD10/CDC42/PSMB1/PSMD7/PSMB3/PSMC5/PSMD11	41
BP	GO:0007164	establishment of tissue polarity	41/4749	124/18670	0.03447	0.175	0.1423	SAPCD2/RAC1/VANGL1/TP63/NKD1/TIAM1/CTHRC1/PSMD8/DVL3/PSMD1/PSMD2/FZD6/PTK7/PSMF1/SMURF1/DVL1/PSMD9/AP2S1/PSMA5/WNT7A/PSMB7/PSMD5/WDR1/PSME2/BRSK2/SFRP1/RSPO3/PSMB5/MLLT3/PSMB4/PSMA3/MED12/PARD6A/FZD5/PSMD10/CDC42/PSMB1/PSMD7/PSMB3/PSMC5/PSMD11	41
BP	GO:1902807	negative regulation of cell cycle G1/S phase transition	43/4749	131/18670	0.03482	0.1766	0.1437	GTSE1/E2F7/E2F8/CDK1/CDKN1A/AURKA/KANK2/CDKN2B/KLF4/ZNF385A/GPNMB/PML/E2F1/PLK2/BAX/BTN2A2/CDC25C/CDKN2C/GADD45A/CCNB1/SFN/RPL26/CDK2/RFWD3/CDK2AP2/PKD2/CCL2/FBXO31/CARM1/CNOT3/EZH2/TFDP2/MUC1/CDKN2A/MDM4/RBL2/CNOT7/GIGYF2/GML/CHEK2/ATM/ZNF655/CCND1	43
BP	GO:0046638	positive regulation of alpha-beta T cell differentiation	18/4749	47/18670	0.03535	0.179	0.1456	CD86/IL18/NLRP3/CD83/CD80/CBFB/TNFSF4/LGALS9/FOXP3/IL4R/HLX/PNP/AP3D1/IL12RB1/RIPK2/RARA/ZAP70/IL23A	18
BP	GO:1903580	positive regulation of ATP metabolic process	18/4749	47/18670	0.03535	0.179	0.1456	CDK1/PFKFB3/ENO1/ENTPD5/STAT3/CCNB1/VCP/HTR2A/PFKFB4/PINK1/PFKFB2/PARK7/IL4/ISCU/INSR/NUPR1/TAZ/P2RX7	18
BP	GO:0030901	midbrain development	31/4749	90/18670	0.03543	0.1791	0.1457	TTBK1/YWHAH/YWHAE/SYNGR3/HSPA5/FOXB1/CNP/MSX1/SEC16A/MAPKAP1/FZD6/KAT2A/FGF9/NDRG2/YWHAQ/GDF7/BASP1/CKB/GNB4/INA/GLUD1/PADI2/DLG5/SMAD1/SFRP1/SIRT2/LRP6/OTX2/ZNF148/CDC42/ACTB	31
BP	GO:1903035	negative regulation of response to wounding	31/4749	90/18670	0.03543	0.1791	0.1457	CD109/CDKN1A/DUSP10/PDGFA/PLAUR/ANXA2P2/CEACAM1/SPP1/CD9/PROS1/TMPRSS6/PROC/PLAU/SERPINE1/ADTRP/RGMA/ANXA2/PLAT/ABAT/CLASP2/ANXA5/VTN/CRK/KLKB1/SERPING1/CD34/PTPRS/SIGLEC10/RTN4R/PDGFB/TFPI	31
BP	GO:0009314	response to radiation	131/4749	448/18670	0.03604	0.1821	0.1481	EGR1/AURKB/PBK/TICRR/CDKN1A/DTL/ICAM1/CASP9/NTRK1/BCL3/TREX1/UBE2A/FANCG/CDK5/CDC25A/RAD54L/PML/PLEKHB1/DDB2/HSPA5/PPP1CB/MSH6/FOXB1/CRIP1/BRCA2/BAX/UBE2B/CXCL10/BRAT1/GADD45A/CCDC66/CTNS/MTOR/FEN1/GPX1/RAD51/HYAL3/RAD51AP1/CCR4/RPL26/TP53BP1/DYNLRB1/ARRB1/RIC8A/BMF/RRM1/CRY1/RFWD3/ATF4/TOPBP1/PER2/XRCC6/ASNS/CRTC1/UNC119/PITPNM1/CIRBP/ZRANB3/N4BP1/GUCA1C/BHLHE40/CCK/NMT1/NAMPT/PTPRC/PIAS1/ERCC8/FIGNL1/TRIM13/BAK1/DRD1/TANK/TP53INP1/RNF8/SLC4A10/RBM4B/TANC1/ERCC5/CNGA1/BRCC3/GPR52/ELK1/JUN/FMR1/ERCC2/CHEK1/GTF2H2/ECT2/PDC/AEN/RBL2/BCL2L1/CYBA/YAP1/NPS/SEMA5B/IFI16/SFRP1/NHEJ1/AANAT/ATR/CHEK2/GNAQ/MTA1/PER3/FNTB/SMC1A/GTF2H5/CAMKMT/XPA/CCL7/FOS/OGG1/ATM/NUCKS1/WRN/TGFB1/CLK2/NET1/MGMT/CCND1/INIP/GATA3/PDE6B/ERCC1/FBXO4/TIPIN/RNF168/RAD9A/SIRT1/DUSP1	131
BP	GO:0042594	response to starvation	60/4749	191/18670	0.03627	0.1831	0.149	CDKN1A/PPARG/GAS2L1/DSC2/MTMR3/ATF3/EIF4EBP1/HSPA5/ZFP36/DHODH/MAP1LC3A/PMAIP1/MTOR/ITFG2/DAP/HCRT/HMGCL/ATF4/NUAK2/ASNS/AMBRA1/FOXO1/FAS/PICK1/MAP3K5/WDR24/C12orf66/OXCT1/ULK1/GBA/DDIT3/JUN/SLC38A2/MYBBP1A/KIAA1324/ZC3H12A/KLF10/IFI16/KRT20/NPRL3/SFRP1/ADM/PIK3C3/EIF2AK3/WDR45/MAX/RRP8/PIK3R4/RALB/RRAGB/WRN/ATG7/BCAS3/MAPK1/LRP11/SESN2/SEH1L/SREBF2/SIRT1/NPRL2	60
BP	GO:1990868	response to chemokine	33/4749	97/18670	0.03654	0.1835	0.1493	CXCL13/WNK1/CCL20/CCL3L3/CXCR6/CCL22/CCR1/CCRL2/CXCL10/DOCK8/CCR6/CCR2/CCR4/SLC12A2/CCL3/CCR5/CCL2/GPR35/CCL17/CCL18/CXCL9/CXCL2/CXCL3/CCR8/ZC3H12A/PADI2/CCL23/CCL7/PPBP/CCL15/CXCR5/CX3CR1/DUSP1	33
BP	GO:1990869	cellular response to chemokine	33/4749	97/18670	0.03654	0.1835	0.1493	CXCL13/WNK1/CCL20/CCL3L3/CXCR6/CCL22/CCR1/CCRL2/CXCL10/DOCK8/CCR6/CCR2/CCR4/SLC12A2/CCL3/CCR5/CCL2/GPR35/CCL17/CCL18/CXCL9/CXCL2/CXCL3/CCR8/ZC3H12A/PADI2/CCL23/CCL7/PPBP/CCL15/CXCR5/CX3CR1/DUSP1	33
BP	GO:0048511	rhythmic process	89/4749	295/18670	0.03656	0.1835	0.1493	EGR1/EGR3/TWIST1/EGR2/RELB/CDK1/CSF2/TYRO3/PPARG/DTL/TOP2A/ADORA2A/NTRK2/HLF/NTRK1/TIMP4/CDK5/PSPC1/ENOX1/SFPQ/ARNTL2/PML/TYMS/NFKB2/HSPA5/ATF5/PPP1CB/USP9X/SERPINE1/DBP/MTOR/PLEKHA1/SRC/NKX2-1/PAM/ARRB1/NTRK3/AXL/CRY1/TGFB3/ATF4/PER2/ZFHX3/CRTC1/MAP2K6/BHLHE40/RORC/NAMPT/KDM5B/KLF9/EZH2/TIMELESS/SP1/RBM4B/KDM8/JUN/UBE3A/FBXW11/MYBBP1A/PHLPP1/ARNTL/TPH1/KLF10/SIAH2/NPS/ZNF830/NDUFA9/BTRC/GHRL/BHLHE41/ADIPOQ/CPT1A/ESR1/PASD1/KDM5A/AANAT/GNAQ/MTA1/PER3/ADAMTS1/ID1/ATG7/CUL4A/HAS2/ADNP/CLDN4/NCOR1/MC3R/SIRT1	89
BP	GO:1903311	regulation of mRNA metabolic process	97/4749	324/18670	0.0366	0.1835	0.1493	TIRAP/YWHAZ/SERBP1/ZFP36/E2F1/HSPA1A/ZC3H12D/NUP98/PLEKHN1/MTOR/CCNB1/SMU1/IWS1/PTBP1/PSMD8/HNRNPA0/RNPS1/TNRC6B/SRSF4/UBB/PSMD1/PSMD2/ZC3H3/PSMF1/CIRBP/UPF1/RPS27A/RNF40/ZFP36L2/SLTM/FAM172A/PRKCA/ALKBH5/RBM46/UBA52/SUPT6H/MEX3D/PSMD9/PSMA5/CELF6/RBM4B/RBM23/SF3B4/FMR1/PSMB7/DDX17/MBNL3/RBM17/EXOSC2/PSMD5/ZC3H12A/VIM/PSME2/ELAVL1/PRPF19/CNOT7/CSDC2/YTHDF3/C9orf78/FASTKD3/MAGOH/RBMY1B/PRDX6/METTL16/TNFSF13/SAMD4B/GIGYF2/PSMB5/RBM38/RBM11/MAPKAPK2/ZC3HAV1/YBX1/ZFP36L1/CPEB1/PSMB4/C1QBP/CPSF6/HNRNPL/PSMA3/TBRG4/AXIN2/PAPOLA/RBM3/NCBP2/PSMD10/CWC22/PSMB1/PSMD7/PSMB3/PSMC5/TNPO1/KHSRP/YTHDC1/EXOSC9/BARD1/PSMD11	97
BP	GO:0007019	microtubule depolymerization	17/4749	44/18670	0.03691	0.1835	0.1493	KIF2C/KIF24/KIF18A/CKAP2/ARHGEF2/STMN3/FGF13/STMN1/CLASP2/MID1/MAP1S/TRIM54/MAP1A/APC/NCKAP5/KIF19/CKAP5	17
BP	GO:0035307	positive regulation of protein dephosphorylation	17/4749	44/18670	0.03691	0.1835	0.1493	SPPL3/MTOR/CDCA2/PTBP1/CD33/PINK1/PTPRC/ITGA1/LILRB2/GBA/PPP1R16B/CAMTA1/PPP1R15A/SLC39A10/TGFB1/PPP1R12A/CDH5	17
BP	GO:1903214	regulation of protein targeting to mitochondrion	17/4749	44/18670	0.03691	0.1835	0.1493	BNIP3L/BAG4/USP36/SAE1/BAP1/PDCD5/PARL/HPS4/PINK1/RAC2/BAG3/GSK3A/RHOU/UBL5/HSPA1L/FZD5/SREBF2	17
BP	GO:0000185	activation of MAPKKK activity	6/4749	11/18670	0.03717	0.1835	0.1493	GADD45G/TNF/GADD45A/TRAF7/TAB1/MAP4K1	6
BP	GO:0003174	mitral valve development	6/4749	11/18670	0.03717	0.1835	0.1493	TWIST1/NOTCH1/DCHS1/SMAD6/ZFPM1/GJA5	6
BP	GO:0010172	embryonic body morphogenesis	6/4749	11/18670	0.03717	0.1835	0.1493	GREM2/CLASP2/IFT122/MAB21L2/ZNF281/PHLDB1	6
BP	GO:0032494	response to peptidoglycan	6/4749	11/18670	0.03717	0.1835	0.1493	NLRP3/IRF5/CARD9/IRAK3/NOD2/RIPK2	6
BP	GO:0033632	regulation of cell-cell adhesion mediated by integrin	6/4749	11/18670	0.03717	0.1835	0.1493	CXCL13/WNK1/SWAP70/FERMT3/PIEZO1/CD3E	6
BP	GO:0034115	negative regulation of heterotypic cell-cell adhesion	6/4749	11/18670	0.03717	0.1835	0.1493	WNK1/IL10/KLF4/IL1RN/MYADM/ADIPOQ	6
BP	GO:0042023	DNA endoreduplication	6/4749	11/18670	0.03717	0.1835	0.1493	E2F7/E2F8/SMC3/MSH6/FBXO5/SMC1A	6
BP	GO:0046512	sphingosine biosynthetic process	6/4749	11/18670	0.03717	0.1835	0.1493	GBA/ACER1/ACER2/ASAH2/ASAH2B/SPHK2	6
BP	GO:0060525	prostate glandular acinus development	6/4749	11/18670	0.03717	0.1835	0.1493	NOTCH1/TP63/WDR77/RXRA/SFRP1/ESR1	6
BP	GO:0070106	interleukin-27-mediated signaling pathway	6/4749	11/18670	0.03717	0.1835	0.1493	EBI3/STAT3/IL27RA/CANX/STAT1/JAK1	6
BP	GO:0070587	regulation of cell-cell adhesion involved in gastrulation	6/4749	11/18670	0.03717	0.1835	0.1493	WNK1/IL10/KLF4/IL1RN/MYADM/ADIPOQ	6
BP	GO:0070673	response to interleukin-18	6/4749	11/18670	0.03717	0.1835	0.1493	IL18/IL18BP/ALOX5/IL18R1/RIPK2/PDGFB	6
BP	GO:0072611	interleukin-13 secretion	6/4749	11/18670	0.03717	0.1835	0.1493	LGALS9/TNFRSF21/PAEP/LILRA5/SPHK2/GATA3	6
BP	GO:0090657	telomeric loop disassembly	6/4749	11/18670	0.03717	0.1835	0.1493	TERF1/RECQL4/POT1/XRCC3/WRN/TERF2	6
BP	GO:1900112	regulation of histone H3-K9 trimethylation	6/4749	11/18670	0.03717	0.1835	0.1493	SMARCB1/LMNA/ZNF304/DMRTC2/KDM4C/SIRT1	6
BP	GO:1900115	extracellular regulation of signal transduction	6/4749	11/18670	0.03717	0.1835	0.1493	DAND5/GREM2/LRPAP1/ZNF653/CD46/CER1	6
BP	GO:1900116	extracellular negative regulation of signal transduction	6/4749	11/18670	0.03717	0.1835	0.1493	DAND5/GREM2/LRPAP1/ZNF653/CD46/CER1	6
BP	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	6/4749	11/18670	0.03717	0.1835	0.1493	ATF3/HSPA5/ATF4/DDIT3/CEBPB/MBTPS2	6
BP	GO:2000615	regulation of histone H3-K9 acetylation	6/4749	11/18670	0.03717	0.1835	0.1493	SMARCB1/NAP1L2/CHEK1/SPHK2/ZNF451/GATA3	6
BP	GO:2000786	positive regulation of autophagosome assembly	6/4749	11/18670	0.03717	0.1835	0.1493	ULK1/KIAA1324/LRSAM1/PIP4K2A/RALB/PIP4K2B	6
BP	GO:0097479	synaptic vesicle localization	52/4749	163/18670	0.03718	0.1835	0.1493	ADORA2A/RIMS3/CDK5/SYN1/NCS1/CHRNA5/STX11/BLOC1S6/P2RX1/SYT4/SNAP47/HTR2A/BLOC1S1/CAMK2A/CNIH2/SNAP29/PFN2/SLC2A4/BLOC1S4/APBA2/STX1B/PINK1/DVL1/AP3D1/SCRIB/STX19/DRD1/SNAP23/DTNBP1/RAB27A/WNT7A/PPFIA3/CNR1/FMR1/SYT11/AP3M2/ERC2/BRSK2/SNAPIN/NAPB/DNM1/STX2/DOC2B/PRKCB/P2RY1/SYN2/CACNB2/FBXL20/AP3B2/SV2A/P2RX7/TRIM9	52
BP	GO:0051480	regulation of cytosolic calcium ion concentration	106/4749	357/18670	0.0373	0.1835	0.1493	CXCL13/GNA15/FPR1/CXCR6/PTPN6/NMB/FPR3/CCR1/CDK5/ANXA2P2/CCRL2/YWHAE/CHERP/PML/HMGB1/CDH23/JSRP1/CHRNA10/NCS1/NOL3/BAX/CXCL10/SPPL3/TRPC1/ANXA2/SWAP70/CCR6/CCR2/MYO5A/HCRT/CCR4/P2RX1/TGM2/F2RL2/PDE4D/HTR2A/CCL3/PTGER4/SRI/CYSLTR1/PKD2/RIC3/CCR5/HTT/S1PR1/GPR33/GPR35/GSTO1/TPCN1/PTPRC/BCAP31/CORO1A/TRPM4/RASA3/CXCL9/P2RY10/BAK1/DRD1/FKBP1A/ATP2B4/LRP1/DDIT3/THY1/CD19/BDKRB2/CNR1/NTSR1/FPR2/C3AR1/PRKCE/PTGER2/CCR8/CYBA/LACRT/GPR32/TBXA2R/PTGER1/IL13/CALB2/ADM/GHRL/CAMK2D/P2RX5/PRNP/ESR1/F2R/FZD9/LRP6/P2RY1/TRPC7/CACNB2/NPFF/PLCB1/TGFB1/TMEM64/GALR2/TRPC5/CXCR5/P2RX7/CX3CR1/PDE6B/GIPR/SLC35G1/FYN/DLG4/GTF2I	106
BP	GO:0009267	cellular response to starvation	48/4749	149/18670	0.0373	0.1835	0.1493	CDKN1A/GAS2L1/DSC2/MTMR3/ATF3/HSPA5/MAP1LC3A/PMAIP1/MTOR/ITFG2/DAP/ATF4/NUAK2/ASNS/AMBRA1/FOXO1/FAS/PICK1/MAP3K5/WDR24/C12orf66/GBA/JUN/SLC38A2/MYBBP1A/KIAA1324/ZC3H12A/KLF10/IFI16/KRT20/NPRL3/SFRP1/PIK3C3/EIF2AK3/WDR45/MAX/RRP8/PIK3R4/RALB/RRAGB/WRN/ATG7/MAPK1/SESN2/SEH1L/SREBF2/SIRT1/NPRL2	48
BP	GO:0031294	lymphocyte costimulation	21/4749	57/18670	0.03738	0.1835	0.1493	CD86/CD80/RAC1/PDCD1/PTPN6/TNFSF4/CTLA4/SRC/PAK1/GRAP2/EFNB1/LGALS1/PAK3/PDCD1LG2/CD3E/CARD11/CDC42/HHLA2/KLRK1/FYN/PAK2	21
BP	GO:0042743	hydrogen peroxide metabolic process	21/4749	57/18670	0.03738	0.1835	0.1493	RAC1/NOXA1/CYBB/CTNS/GPX1/STAT3/PRDX3/PRDX5/HBA2/PINK1/PARK7/RAC2/MPO/ZNF205/CYBA/HBG1/PRDX6/HBB/NNT/PRDX1/FYN	21
BP	GO:0048008	platelet-derived growth factor receptor signaling pathway	21/4749	57/18670	0.03738	0.1835	0.1493	VEGFA/TXNIP/NR4A3/PDGFA/CSRNP1/MYO1E/HIP1/PTPN1/PLEKHA1/PLAT/SRC/ARID5B/HIP1R/LRP1/HGS/RAPGEF1/ADIPOQ/F3/FER/BCR/PDGFB	21
BP	GO:0050819	negative regulation of coagulation	21/4749	57/18670	0.03738	0.1835	0.1493	PDGFA/PLAUR/ANXA2P2/CEACAM1/CD9/PROS1/TMPRSS6/PROC/PLAU/SERPINE1/ADTRP/ANXA2/PLAT/ABAT/ANXA5/VTN/KLKB1/SERPING1/CD34/PDGFB/TFPI	21
BP	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	21/4749	57/18670	0.03738	0.1835	0.1493	RAC1/PIM3/TIAM1/ARRB1/ENY2/C2CD2L/SRI/TRPM4/NADK/OXCT1/LRP1/PRKCE/SIDT2/LRP5L/BRSK2/GHRL/SLC9B2/NDUFAF2/PDX1/SYBU/BAD	21
BP	GO:0075733	intracellular transport of virus	21/4749	57/18670	0.03738	0.1835	0.1493	SEC13/KPNA2/NUP98/BST2/UBB/NUP153/RPS27A/UBA52/NUP88/FMR1/KPNA3/POM121C/NUP205/RAE1/NUP50/NUP93/NUP35/AAAS/NUP62/SEH1L/TRIM15	21
BP	GO:0072503	cellular divalent inorganic cation homeostasis	143/4749	493/18670	0.03791	0.186	0.1513	VDR/CXCL13/GNA15/FPR1/CXCR6/PTPN6/NMB/FPR3/CCR1/CDK5/ANXA2P2/SLC39A7/CCRL2/YWHAE/CHERP/PML/KCTD17/HMGB1/CDH23/JSRP1/CHRNA10/NCS1/NOL3/BAX/CXCL10/MT1E/SPPL3/TRPC1/SLC25A23/ANXA2/MT2A/SWAP70/CCR6/ATP13A1/CCR2/MYO5A/HCRT/CCR4/P2RX1/TGM2/ATP13A4/F2RL2/PDE4D/HTR2A/ATP2A1/CCL3/ATP13A2/PTGER4/SRI/MICU1/CYSLTR1/HERPUD1/PKD2/ATF4/RIC3/EPHX2/CCR5/HTT/S1PR1/GPR33/GPR35/ATP1B1/CASR/MT1X/GSTO1/TPCN1/PTPRC/BCAP31/CORO1A/TRPM4/RASA3/ANXA5/CXCL9/AP3D1/P2RY10/MT1H/BAK1/DRD1/FKBP1A/ATP2B4/LRP1/DDIT3/THY1/CD19/BDKRB2/CNR1/NTSR1/SLC24A3/MT1G/FPR2/C3AR1/GPR12/PRKCE/PTGER2/CCR8/CYBA/TMEM203/LACRT/GPR32/TBXA2R/PTGER1/IL13/CALB2/ADM/GHRL/S100A8/CAMK2D/P2RX5/PRNP/ESR1/F2R/MT1A/FZD9/LRP6/PRKCB/P2RY1/TRPC7/CCL23/HEXB/MT1B/CACNB2/MT1M/CCL7/NPFF/PLCB1/SLC39A10/TGFB1/TMEM64/CCL15/GALR2/SV2A/TRPC5/CDH5/CXCR5/P2RX7/CX3CR1/PDE6B/GIPR/MT1F/SLC35G1/FYN/DLG4/GTF2I	143
BP	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	27/4749	77/18670	0.03811	0.1866	0.1518	EXO1/FEN1/TSEN2/NUDT16/RNASE8/TSEN15/NOL9/POP5/RNASEH2A/TSEN34/ELAC1/YBEY/NOP14/UTP20/TSNAX/ZC3H12A/BOP1/UTP23/ABT1/ERN1/ENDOV/SMG6/DICER1/RPP30/RCL1/PIWIL4/TSN	27
BP	GO:1903509	liposaccharide metabolic process	37/4749	111/18670	0.03812	0.1866	0.1518	B3GNT5/NAGA/CTSA/NEU4/GLB1/GBGT1/GM2A/NEU1/BAX/ITGB8/FA2H/PIGK/PIGH/DPM2/ST8SIA1/GAL3ST2/SUMF1/ST6GALNAC4/PIGQ/PIGO/GBA/PIGC/PIGW/B4GALT5/NEU3/GALC/HEXB/GAL3ST4/PIGM/SUMF2/PIGA/ST8SIA3/FUCA1/ALDH5A1/ST6GALNAC6/PIGG/PIGT	37
BP	GO:1904019	epithelial cell apoptotic process	37/4749	111/18670	0.03812	0.1866	0.1518	JAG2/ICAM1/IL10/E2F2/TNF/ZFP36/E2F1/GSN/ECSCR/SERPINE1/COL18A1/MTOR/PDCD4/HMOX1/HLA-G/CFLAR/PAK4/SFRP4/CCL2/TCF7L2/BID/MAP3K5/STK3/PRKCI/BCL2L1/IL13/PIAS4/IL4/KRIT1/ZFP36L1/NUPR1/ARF6/CD248/SEMA5A/GATA3/PDX1/BAD	37
BP	GO:0032387	negative regulation of intracellular transport	24/4749	67/18670	0.03816	0.1866	0.1518	CDK5/LGALS9/BAG4/HMOX1/SYT4/CNIH2/NUP153/UBE2G2/CRYAA/INSIG1/CHP1/PARK7/FMR1/CABP1/SNX12/BAG3/RABGEF1/RAB23/ADIPOQ/ARHGAP1/UBAC2/GDI1/USP17L2/BARD1	24
BP	GO:0006367	transcription initiation from RNA polymerase II promoter	59/4749	188/18670	0.03828	0.1869	0.152	VDR/NR4A1/NOTCH1/CDK1/CDKN1A/NR4A3/PPARG/NR3C2/E2F2/SRF/CBFB/THRA/MAML1/HMGB1/BAX/TEAD3/ESRRA/MED20/WNT10B/NR3C1/MAML2/CCNB1/MED4/WWTR1/RBPJ/RUNX2/RORC/CDK7/TAF1L/TAF9B/MED24/TAF6L/TAF10/RXRA/NRBP1/POLR2I/ERCC2/TAF11/GTF2H2/POLR2C/YAP1/GTF2H1/TAF7/ESR1/TAF6/MNAT1/POLR2J/MED12/GTF2H5/PPARD/TEAD4/POLR2A/CCNC/ZNF451/NR2C1/RARA/CCND1/PSMC5/GTF2I	59
BP	GO:0043902	positive regulation of multi-organism process	59/4749	188/18670	0.03828	0.1869	0.152	NOTCH1/TOP2A/AURKA/CSF1R/IFIT1/GAPDH/GRN/CLEC7A/ANXA2P2/LGALS9/SMC3/CHMP2B/KPNA2/ANXA2/SMARCB1/HYAL3/PPIH/HAVCR2/CD74/LGALS1/CD180/PGLYRP3/SMARCA4/TBC1D20/PRKCA/CFL1/SP1/ARG1/POLR2I/JUN/FMR1/TAF11/RAD23A/ZNF639/CYBA/POLR2C/CNOT7/SIRT2/RIPK2/LRSAM1/P2RY1/C1QBP/CHMP2A/STAU1/KLK5/TRAF6/POLR2J/STOM/NUCKS1/ANKRD17/PLCB1/POLR2A/PLB1/ZCCHC3/PTAFR/USP17L2/CHMP3/BAD/TRIM15	59
BP	GO:0010256	endomembrane system organization	128/4749	438/18670	0.03847	0.1873	0.1524	CDK1/SQSTM1/CIT/COL5A1/ZNF385A/SURF4/PDE4DIP/CCNB2/REEP2/CORO1C/GORASP1/ATP8B4/PPP2R1A/YWHAZ/REEP3/SNX9/CHMP2B/RFX2/MYH10/GSN/PLK1/PLEKHM2/TMEM43/PLSCR4/ZFYVE27/ABCD1/LMNA/SNF8/CCNB1/STX5/FA2H/SEC16A/ABCD2/SYT4/CLU/BLOC1S1/REEP4/STAM/VPS33B/MYOF/CCDC136/SUN2/HTT/NPLOC4/MICALL1/COG7/SYNGR2/SGTA/TMED3/SPTBN1/PTPRC/TBC1D20/PRKCA/MPP5/NDRG1/CLASP2/TLCD1/VPS51/TRAM2/ABCA1/AP3D1/FLOT1/LEMD3/PPP2CA/PI4K2A/BANF1/SPAG4/TMED9/COG1/DTNBP1/HGS/RAB27A/HOOK2/EMD/STK25/GBF1/SNX19/PLSCR2/TMEM170A/TMED10/PARP11/SYT11/TMED5/SNX33/STX16/RAB38/IST1/SRGN/LMAN2/ATP8B3/TMED4/PIK3C3/RAB2A/EIF2AK3/SYNGR1/DNM1/CHMP1A/MYH9/F2R/ARV1/COG3/STX2/NSFL1C/SERP1/PRKCB/PACSIN1/CHMP2A/RAB1A/NUP93/WHAMM/EHD3/NEK9/ANO4/TMED1/ALS2CL/TMEM33/BCAS3/CDC42/TMED6/TMF1/TRAPPC12/MAPK1/P2RX7/CHMP3/LPIN1/REEP1/USO1/UBL4A	128
BP	GO:0045005	DNA-dependent DNA replication maintenance of fidelity	16/4749	41/18670	0.03847	0.1873	0.1524	BRCA2/RAD51/TONSL/RFWD3/ZRANB3/TIMELESS/POLE/SAMHD1/ZNF830/EME1/DDX11/DNA2/ETAA1/NUCKS1/WRN/TIPIN	16
BP	GO:0061028	establishment of endothelial barrier	16/4749	41/18670	0.03847	0.1873	0.1524	IL1B/VEGFA/ICAM1/TNF/PROC/TJP2/MYADM/PDE4D/EZR/WNT7A/PPP1R16B/RAPGEF1/RAPGEF2/PTPRS/FASN/CDH5	16
BP	GO:0070317	negative regulation of G0 to G1 transition	16/4749	41/18670	0.03847	0.1873	0.1524	RBBP8/E2F1/UXT/RAD51/RYBP/CBX5/HLA-G/PHC3/EED/EZH2/TFDP2/PCGF6/CHEK1/RRM2/MAX/BMI1	16
BP	GO:0051048	negative regulation of secretion	73/4749	238/18670	0.03851	0.1873	0.1524	LIF/IL1B/NOTCH1/NLRP3/WNK1/IL10/TLR8/PIM3/RAB11FIP1/NMB/CEACAM1/LGALS9/PML/TNF/TNFRSF4/ADRA2B/CD200/BTN2A2/TNFRSF21/FOXP3/ADTRP/IL1R2/RSAD2/FRMD4A/CCR2/HMOX1/ABAT/SYT4/PTGER4/ENY2/CRY1/CD74/ENHO/RSC1A1/TIFAB/EZR/ANXA5/PSMD9/IL27RA/OSM/GNAI2/CNR1/C1QTNF3/TLR6/RAB11FIP3/FMR1/ACVR1C/ANXA4/DEFB114/SYT11/VAMP3/TACR2/SRGN/ZC3H12A/RABGEF1/LILRA5/SFRP1/GHRL/ADIPOQ/CD34/TNFRSF1B/RAB11FIP5/F2R/CSN2/P2RY1/HDAC9/BCR/CARD8/PFKL/NPFF/NDUFAF2/LRRC32/TRIM9	73
BP	GO:0031929	TOR signaling	41/4749	125/18670	0.03902	0.1897	0.1543	FAM83D/SEC13/DYRK3/RFFL/EIF4EBP1/SYAP1/AKT3/MTOR/ITFG2/TTI1/MAPKAP1/RPS6/SIK3/PINK1/WDR24/C12orf66/DDIT4/TIPRL/GBA/SLC38A9/SH3BP4/DEPTOR/ARNTL/GSK3A/HTR6/NPRL3/CARD11/FBXO9/UBR2/LAMTOR4/LAMTOR2/KLHL22/TBCK/ATM/RRAGB/GATA3/SESN2/SEH1L/MLST8/SIRT1/NPRL2	41
BP	GO:0009066	aspartate family amino acid metabolic process	20/4749	54/18670	0.03934	0.1909	0.1553	SDS/SMS/OGDH/ASNS/GCAT/MRI1/DLST/MTHFD1/BHMT/MTRR/MTAP/GNMT/ENOPH1/AASDHPPT/MTR/ALDH7A1/PLOD3/NIT2/ASNSD1/BHMT2	20
BP	GO:0030042	actin filament depolymerization	20/4749	54/18670	0.03934	0.1909	0.1553	MICAL1/CAPZB/GSN/MICAL2/SWAP70/TMOD2/CAPG/PDXP/ADD3/SPTBN1/TRIOBP/TWF2/CFL1/SPTAN1/CAPZA1/WDR1/MICAL3/VILL/SEMA5A/ADD2	20
BP	GO:0001503	ossification	117/4749	398/18670	0.03939	0.191	0.1554	TWIST1/EGR2/NOTCH1/ACP5/RASSF2/ISG15/TP53INP2/CBFB/CCR1/GPNMB/BMP2K/SPP1/TP63/PTCH1/THRA/PLXNB1/TNF/CSF1/SEMA7A/SKI/RPL38/ESRRA/SBNO2/DCHS1/WNT10B/CLIC1/NBR1/SNAI1/FBXO5/PPARGC1B/CTHRC1/NAB2/LIMD1/CSGALNACT1/GNAS/RPS15/CCL3/PTGER4/TGFB3/WWTR1/PTHLH/FGF9/RBPJ/MN1/COL6A1/PHEX/IGFBP3/FAM20C/ZBTB40/SMAD6/BCOR/RUNX2/S1PR1/PDLIM7/JAG1/CASR/SMURF1/LRP4/ATRAID/COL11A1/TRPM4/CHRDL2/MEF2D/FIGNL1/EXT1/SBDS/IFITM1/WWOX/SOX8/NAB1/CYP27B1/TOB2/ERCC2/SH3PXD2B/ACVR2B/MYBBP1A/CEBPB/LRP5L/SOX11/SRGN/TPH1/KLF10/RDH14/FBL/BGLAP/SMAD1/SFRP1/EIF2AK3/IFT80/RRBP1/SUCO/DLX5/FZD9/CLEC5A/SEMA4D/FASN/TXLNG/TRAF6/PAM16/BMP3/FBXL15/AXIN2/TMEM119/PBX1/TNFSF11/XYLT1/CER1/ID1/TGFB1/TMEM64/MAPK1/ASF1A/AMELX/DHRS3/P2RX7/RRAS2/ILK	117
BP	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	34/4749	101/18670	0.03965	0.1921	0.1563	KIF2C/KIF4A/KIF15/KIF23/SEC13/RACGAP1/KIF18A/IFI30/SEC24D/CAPZB/HLA-DQB2/KIF11/HLA-DMA/KLC1/CENPE/KIF4B/CD74/CTSF/DCTN5/HLA-DPA1/HLA-DRA/AP1S1/AP2S1/CTSD/LAG3/CAPZA1/KIF3C/HLA-DMB/HLA-DQA2/ACTR1A/CANX/HLA-DPB1/TRAF6/HLA-DRB1	34
BP	GO:0050818	regulation of coagulation	29/4749	84/18670	0.03972	0.1923	0.1565	PDGFA/PLAUR/HPSE/ANXA2P2/CEACAM1/CD9/PROS1/TMPRSS6/TLR4/PROC/PLAU/SERPINE1/ADTRP/ANXA2/VKORC1/PLAT/ABAT/PRKCA/ANXA5/VTN/ENPP4/KLKB1/TBXA2R/SERPING1/F3/CD34/F2R/PDGFB/TFPI	29
BP	GO:0008654	phospholipid biosynthetic process	79/4749	260/18670	0.03995	0.193	0.157	MBOAT7/PTPN13/SGMS1/PDGFA/CPNE7/DOLPP1/SBF1/PCTP/MFSD2A/SGMS2/MTMR3/AGPAT3/AGPAT2/PLEKHA1/PMVK/FDPS/FITM2/DGKZ/INPP4A/FABP5/PLA2G12A/HTR2A/PIGK/FITM1/LPCAT2/SH3YL1/PIGH/PIK3R5/PITPNM1/PIKFYVE/DPM2/MTMR9/PLEKHA2/LPCAT3/PIP5K1B/ACP6/PIGQ/PI4K2A/PIGO/STARD10/FPR2/PLEKHA8/AGAP2/LPCAT4/PIGC/RAB38/PTPMT1/MTMR14/PIGW/PIK3C3/PLA2G2A/TAMM41/LCLAT1/SPHK2/HEXB/PIP4K2A/PIK3R4/PIGM/PTDSS1/PIGA/AGK/PIP4K2B/PLA2G5/ATM/PPARD/TAZ/DOLK/PIP5K1A/IDI2/GPAT2/MBOAT1/PLEKHA3/PDGFB/PIGG/LPIN1/PIGT/CRLS1/PGS1/SLC44A1	79
BP	GO:0006298	mismatch repair	15/4749	38/18670	0.04	0.193	0.157	TP73/EXO1/TREX1/HMGB1/MSH6/PMS2P1/POLD4/RNASEH2A/PMS2P5/AXIN2/MLH3/HDAC10/MUTYH/ERCC1/PMS1	15
BP	GO:0050716	positive regulation of interleukin-1 secretion	15/4749	38/18670	0.04	0.193	0.157	NLRP3/TLR8/HK1/LGALS9/HMGB1/TLR4/LILRA2/CCL3/NOD2/LILRA5/RIPK2/CARD8/FZD5/TRIM16/P2RX7	15
BP	GO:0055069	zinc ion homeostasis	15/4749	38/18670	0.04	0.193	0.157	SLC39A7/MT1E/MT2A/TMC8/ATP13A2/MT1X/AP3D1/MT1H/MT1G/S100A8/MT1A/MT1B/MT1M/SLC39A10/MT1F	15
BP	GO:1905898	positive regulation of response to endoplasmic reticulum stress	15/4749	38/18670	0.04	0.193	0.157	SERINC3/BAX/PTPN1/PMAIP1/HERPUD1/SGTA/BCAP31/BAK1/DDIT3/EDEM2/UBQLN2/ERN1/PPP1R15A/TMEM33/SIRT1	15
BP	GO:0044242	cellular lipid catabolic process	67/4749	217/18670	0.0402	0.1934	0.1573	TWIST1/NAGA/NEU4/PDXDC1/ABHD16A/GM2A/NEU1/MTOR/ADTRP/LDLR/ABCD1/GDPD3/SORL1/MECR/ABCD2/AIG1/FABP5/SLC27A2/MCAT/PPT1/GLYATL2/ACOX2/CYP26C1/GDPD1/TYSND1/ACOT8/LRP1/GBA/CNR1/AMACR/ETFA/PEX2/ACER1/ACER2/BDH2/PLA2G15/PNPLA6/ASAH2/ABHD1/PRDX6/SIRT2/CYP4F12/ADIPOQ/CPT1A/GDE1/ASAH2B/SLC27A4/NEU3/MGST2/ACACB/ETFB/GALC/PCCB/ACAD11/HEXB/ECI1/NUDT19/PECR/FUCA1/PPARD/GPCPD1/PEX13/HADHB/FABP12/SESN2/LPIN1/DECR2	67
BP	GO:0002696	positive regulation of leukocyte activation	112/4749	380/18670	0.04022	0.1934	0.1573	EGR3/EBI3/IL1B/CD86/IL18/CD276/IL21/CDKN1A/NR4A3/NLRP3/DUSP10/IL10/CD83/CD80/RAC1/TTBK1/PDCD1/PTPN6/BCL6/CBFB/SIRPA/TIRAP/TNFSF4/TFRC/CLEC7A/LGALS9/HMGB1/TNFRSF4/IL2RA/TLR4/BTN2A2/FOXP3/GAB2/CTLA4/IL4R/DOCK8/TOX/CCR2/SRC/HLA-G/TP53BP1/LILRB4/BTK/CCL3/HAVCR2/AXL/CD74/PAK1/CD177/CD1D/GRAP2/RPS3/EFNB1/HLX/LGALS1/PPP2R3C/CCL2/PNP/PAK3/DNAJA3/HLA-DPA1/PTPRC/CYLD/CORO1A/HLA-E/CD47/AIF1/AP3D1/SART1/NOD2/LILRB2/IL12RB1/THY1/TLR6/CD46/CLEC4D/IL7R/HLA-DMB/TNFSF9/PDCD1LG2/IL7/CD3E/IL13/CCDC88B/CARD11/LAMP1/TNFSF13/IL4/RIPK2/TYROBP/CD6/MAD2L2/HLA-DPB1/TRAF6/SPHK2/VNN1/ATP11C/TNFSF11/SLC39A10/TGFB1/CDC42/JAK3/RARA/HHLA2/KLRK1/ZAP70/GATA3/PTAFR/BAD/FYN/PAK2/IL23A	112
BP	GO:0007162	negative regulation of cell adhesion	87/4749	289/18670	0.04028	0.1934	0.1573	VEGFA/NOTCH1/CD86/SDC4/WNK1/ADORA2A/IL10/KLF4/CD80/PTPN6/BCL6/IL1RN/PLXNB2/CBFB/TNFSF4/LGALS3/GPNMB/CEACAM1/CORO1C/LGALS9/CD9/NF2/PLXNB1/HMGB1/IL2RA/BTN2A2/SERPINE1/TNFRSF21/FOXP3/ADTRP/MYADM/MMP12/CTLA4/IL4R/SMAD7/SWAP70/SRC/ABAT/HLA-G/TIGIT/HAVCR2/PLXNA1/CD74/CLEC4G/HLX/LGALS1/JAG1/PTPRC/CLASP2/PLXND1/ACTN4/DUSP22/MUC1/CDKN2A/LILRB2/LRP1/ARG1/LAG3/TGFBI/EPB41L5/ERBB2/FXYD5/ADAM22/CEBPB/ACER2/IDO1/DTX1/PDCD1LG2/ZC3H12A/ADAM15/NRARP/ZNF703/DLG5/DACT2/ADIPOQ/PRNP/MAD2L2/SEMA4D/ARHGDIA/AP1AR/TGFB1/BCAS3/SEMA5A/GLMN/JAK3/LRRC32/DUSP1	87
BP	GO:0060135	maternal process involved in female pregnancy	23/4749	64/18670	0.04031	0.1934	0.1573	VDR/LIF/ITGA3/UBE2A/PTGIS/SPP1/LGALS9/PRDM1/MTOR/PRDX3/PAM/HAVCR2/CTSB/ARG1/RXRA/CNR1/CYP27B1/BSG/GHRL/ESR1/NPFF/PPARD/MAPK1	23
BP	GO:0014015	positive regulation of gliogenesis	26/4749	74/18670	0.04032	0.1934	0.1573	LIF/IL1B/NOTCH1/TP73/PPARG/TTBK1/TNF/CSF1/E2F1/MTOR/TSPO/CCR2/ETV5/TIAM1/CCL3/SPINT1/PRKCI/TLR2/LRP1/LTA/SOX8/PRPF19/TNFRSF1B/DICER1/NKX6-2/TGFB1	26
BP	GO:0031670	cellular response to nutrient	26/4749	74/18670	0.04032	0.1934	0.1573	VDR/PPARG/KANK2/CDKN2B/FES/SRF/BCL11A/CYBB/GDAP1/PIM1/HMOX1/P2RY11/AMIGO1/PDXP/USF2/NMRAL1/PHEX/CASR/TRPM4/CYP27B1/CYBA/BGLAP/SFRP1/P2RY1/P2RX7/FYN	26
BP	GO:0032507	maintenance of protein location in cell	26/4749	74/18670	0.04032	0.1934	0.1573	BCL3/HK1/CDK5/PML/HSPA5/HK2/GSN/TSPO/SORL1/KDELR2/SUN2/TMSB4Y/PINK1/EZR/TWF2/INSIG1/SPAG4/PARK7/TOPORS/SYNE3/TMSB15A/ARL2BP/VPS13D/ARL2/SYNE2/BARD1	26
BP	GO:0043507	positive regulation of JUN kinase activity	26/4749	74/18670	0.04032	0.1934	0.1573	TNF/FGD2/PTPN1/MAP3K6/ARHGEF5/TIAM1/MAP3K2/DVL3/PAK1/RPS3/MAP3K5/NRK/MAP3K11/TAOK3/TLR6/FZD8/MAP2K4/TRAF2/MAP4K1/ERN1/RIPK2/TRAF6/BIRC7/TNFSF11/FZD5/MAP3K9	26
BP	GO:0045639	positive regulation of myeloid cell differentiation	31/4749	91/18670	0.041	0.1952	0.1588	LIF/TRIB1/FES/ISG15/IL17A/CCR1/TNF/CSF1/HSPA1A/STAT3/PPARGC1B/GNAS/CD74/JAG1/PRKCA/JUN/CA2/KLF10/IL20/TYROBP/ZFP36L1/TESC/TRAF6/STAT1/TNFSF11/FOS/SLC9B2/TGFB1/TMEM64/POU4F1/IL23A	31
BP	GO:0034470	ncRNA processing	113/4749	384/18670	0.04115	0.1952	0.1588	RPS8/RPL10A/RPS27/RPL35/TSEN2/QTRT1/TRMT12/USP36/NUDT16/XRN2/USB1/FAM98B/RPL5/RPL26/RPS6/RPS15/CTU1/RRP1/MRPS11/RPL7/GTPBP3/TSEN15/ALKBH8/NSUN4/TRMT1/NOP10/ISG20/DDX27/NOL9/BYSL/POP5/RPS19/NSUN5P1/OSGEPL1/PA2G4/ERI3/FAM207A/RIOK1/ELP5/RPS16/SART1/TARBP1/SBDS/RPS9/PUS1/NSUN6/RPL14/NOLC1/TRMT10B/TSEN34/ELAC1/YBEY/SEPHS1/TRMT13/TRPT1/DDX17/TYW1B/TRIT1/ZNHIT3/NOP14/ELP4/EXOSC2/TRMT112/NPM3/DDX54/UTP20/PUSL1/INTS12/METTL8/EMG1/BOP1/UTP23/DUS1L/BTRC/KTI12/FBL/FDXACB1/RRNAD1/SMAD1/METTL16/WDR12/ABT1/TEX10/MTFMT/RPS28/ZCCHC4/CPSF1/RPL7A/MRTO4/ESF1/TRMT10C/MDN1/C9orf64/TUT1/DICER1/URB1/RRP8/RPP30/TRMT1L/RPL11/RPF1/GTF2H5/THG1L/RCL1/UTP3/TFB2M/NSUN2/TRNT1/NGDN/EXOSC9/CDKAL1/SIRT1/PUS10	113
BP	GO:0002712	regulation of B cell mediated immunity	19/4749	51/18670	0.04138	0.1952	0.1588	IL10/PTPN6/BCL6/TNFSF4/TFRC/TNF/FOXP3/TP53BP1/BTK/PTPRC/HLA-E/SUPT6H/IL27RA/LTA/APLF/TNFSF13/IL4/MAD2L2/TGFB1	19
BP	GO:0002889	regulation of immunoglobulin mediated immune response	19/4749	51/18670	0.04138	0.1952	0.1588	IL10/PTPN6/BCL6/TNFSF4/TFRC/TNF/FOXP3/TP53BP1/BTK/PTPRC/HLA-E/SUPT6H/IL27RA/LTA/APLF/TNFSF13/IL4/MAD2L2/TGFB1	19
BP	GO:0048146	positive regulation of fibroblast proliferation	19/4749	51/18670	0.04138	0.1952	0.1588	CDKN1A/PDGFA/CCNA2/ANXA2P2/CDC6/PML/SIRT6/E2F1/ANXA2/CCNB1/CD74/S100A6/FOSL2/JUN/IL13/ESR1/TGFB1/BMI1/PDGFB	19
BP	GO:0051496	positive regulation of stress fiber assembly	19/4749	51/18670	0.04138	0.1952	0.1588	SDC4/RAC1/NF2/FHOD1/MTOR/BAG4/ARHGEF5/TGFB3/PAK1/PFN2/CD47/LIMCH1/S100A10/LIMK1/SH3PXD2B/SFRP1/TPM1/SORBS3/CDC42	19
BP	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	14/4749	35/18670	0.04147	0.1952	0.1588	RPS8/MRPS11/BYSL/RPS19/FAM207A/RPS16/NOP14/UTP20/UTP23/BTRC/ABT1/RCL1/UTP3/NGDN	14
BP	GO:0015695	organic cation transport	14/4749	35/18670	0.04147	0.1952	0.1588	ADORA2A/SLC6A8/SLC25A45/SEC14L1/SLC22A3/OAZ3/SLC38A2/TACR2/SLC25A48/CHRNA3/SLC25A42/SLC22A4/RALBP1/SLC44A1	14
BP	GO:0019076	viral release from host cell	14/4749	35/18670	0.04147	0.1952	0.1588	PML/SMC3/CHMP2B/TRIM25/TRIM26/TRIM62/TRIM13/MID2/IST1/CHMP2A/TRIM35/CHMP3/TRIM15/TRIM5	14
BP	GO:0032801	receptor catabolic process	14/4749	35/18670	0.04147	0.1952	0.1588	FURIN/SNX25/CDK5/ANXA2P2/PTPN1/ANXA2/CAPN1/DTX3L/MYLIP/SMURF1/AP2S1/UVRAG/PIK3R4/TGFB1	14
BP	GO:0033363	secretory granule organization	14/4749	35/18670	0.04147	0.1952	0.1588	ZNF385A/RFX2/SYT4/BLOC1S1/VPS33B/CCDC136/TBC1D20/ABCA1/DTNBP1/SNX19/RAB38/SRGN/F2R/TMF1	14
BP	GO:0035890	exit from host	14/4749	35/18670	0.04147	0.1952	0.1588	PML/SMC3/CHMP2B/TRIM25/TRIM26/TRIM62/TRIM13/MID2/IST1/CHMP2A/TRIM35/CHMP3/TRIM15/TRIM5	14
BP	GO:0035891	exit from host cell	14/4749	35/18670	0.04147	0.1952	0.1588	PML/SMC3/CHMP2B/TRIM25/TRIM26/TRIM62/TRIM13/MID2/IST1/CHMP2A/TRIM35/CHMP3/TRIM15/TRIM5	14
BP	GO:0046131	pyrimidine ribonucleoside metabolic process	14/4749	35/18670	0.04147	0.1952	0.1588	APOBEC3H/DHODH/APOBEC3B/AK3/NME4/UPRT/AICDA/NME3/ENTPD4/CMPK1/CTPS2/UCK2/NME9/NME2	14
BP	GO:0052126	movement in host environment	14/4749	35/18670	0.04147	0.1952	0.1588	PML/SMC3/CHMP2B/TRIM25/TRIM26/TRIM62/TRIM13/MID2/IST1/CHMP2A/TRIM35/CHMP3/TRIM15/TRIM5	14
BP	GO:0052192	movement in environment of other organism involved in symbiotic interaction	14/4749	35/18670	0.04147	0.1952	0.1588	PML/SMC3/CHMP2B/TRIM25/TRIM26/TRIM62/TRIM13/MID2/IST1/CHMP2A/TRIM35/CHMP3/TRIM15/TRIM5	14
BP	GO:0098751	bone cell development	14/4749	35/18670	0.04147	0.1952	0.1588	SRF/PTPN6/ZNF385A/ANXA2P2/LRRK1/ANXA2/SRC/FAM20C/TYROBP/PIP4K2A/TNFSF11/WASF2/SLC9B2/ZFPM1	14
BP	GO:0031056	regulation of histone modification	46/4749	143/18670	0.04173	0.1952	0.1588	TWIST1/LIF/IL1B/VEGFA/BCL6/SPI1/PHF19/ZNHIT1/SETD7/SKI/UBE2B/FOXP3/SMARCB1/LMNA/NAP1L2/CCNB1/IWS1/ARRB1/KAT2A/UBE2N/BCOR/RNF40/ZNF304/PINK1/EED/BRD4/SUPT6H/MUC1/FMR1/CHEK1/C6orf89/MLLT6/CAMK2D/TAF7/KDM5A/DMRTC2/TADA2A/SPHK2/CTBP1/ATM/KDM4C/TGFB1/ZNF451/GATA3/USP17L2/SIRT1	46
BP	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	7/4749	14/18670	0.04174	0.1952	0.1588	RPL35/RPL7/NOL9/ZNHIT3/BOP1/WDR12/URB1	7
BP	GO:0006268	DNA unwinding involved in DNA replication	7/4749	14/18670	0.04174	0.1952	0.1588	MCM4/RAD51/MCM2/MCM7/RECQL5/RECQL4/WRN	7
BP	GO:0006896	Golgi to vacuole transport	7/4749	14/18670	0.04174	0.1952	0.1588	AP3D1/VPS52/AP4M1/LAMP1/VTI1B/EHD3/CCDC91	7
BP	GO:0006999	nuclear pore organization	7/4749	14/18670	0.04174	0.1952	0.1588	NUP98/NUP153/TMEM170A/NUP205/NUP93/NUP35/SEH1L	7
BP	GO:0007100	mitotic centrosome separation	7/4749	14/18670	0.04174	0.1952	0.1588	AURKA/NEK2/KIF11/CHEK1/NSFL1C/MAP9/NUP62	7
BP	GO:0010935	regulation of macrophage cytokine production	7/4749	14/18670	0.04174	0.1952	0.1588	SEMA7A/TLR4/HLA-G/TGFB3/CD74/IRAK3/TGFB1	7
BP	GO:0015780	nucleotide-sugar transmembrane transport	7/4749	14/18670	0.04174	0.1952	0.1588	SLC35A2/SLC35E4/SLC35B1/SLC35D2/SLC35D1/SLC35C1/SLC35B4	7
BP	GO:0035791	platelet-derived growth factor receptor-beta signaling pathway	7/4749	14/18670	0.04174	0.1952	0.1588	PDGFA/HIP1/PTPN1/SRC/HIP1R/LRP1/PDGFB	7
BP	GO:0045953	negative regulation of natural killer cell mediated cytotoxicity	7/4749	14/18670	0.04174	0.1952	0.1588	CEACAM1/LGALS9/HLA-G/HAVCR2/HLA-E/MICA/CRK	7
BP	GO:0046606	negative regulation of centrosome cycle	7/4749	14/18670	0.04174	0.1952	0.1588	CCNF/NEK2/KAT2A/NUBP1/MDM1/TMEM67/CHMP2A	7
BP	GO:0060009	Sertoli cell development	7/4749	14/18670	0.04174	0.1952	0.1588	ICAM1/NTRK1/RAB13/SDC1/FNDC3A/SOX8/ARID4A	7
BP	GO:0071391	cellular response to estrogen stimulus	7/4749	14/18670	0.04174	0.1952	0.1588	ARID5A/SFR1/SFRP1/ESR1/BCAS3/RARA/SRA1	7
BP	GO:0098543	detection of other organism	7/4749	14/18670	0.04174	0.1952	0.1588	CLEC7A/TLR4/CD1D/PGLYRP3/TLR2/NOD2/TLR6	7
BP	GO:1901070	guanosine-containing compound biosynthetic process	7/4749	14/18670	0.04174	0.1952	0.1588	HPRT1/NME4/NME3/IMPDH1/GUK1/NME9/NME2	7
BP	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	7/4749	14/18670	0.04174	0.1952	0.1588	SKIL/ATF3/PEA15/PMAIP1/STK3/SFRP1/TIMP3	7
BP	GO:2001279	regulation of unsaturated fatty acid biosynthetic process	7/4749	14/18670	0.04174	0.1952	0.1588	IL1B/ABCD1/ABCD2/FABP5/CD74/PIBF1/SIRT1	7
BP	GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	22/4749	61/18670	0.04257	0.1987	0.1616	CD86/IL18/NLRP3/CD83/CD80/IRF4/BCL6/CBFB/TNFSF4/LGALS9/HMGB1/FOXP3/IL4R/SMAD7/HLX/IL12RB1/ZC3H12A/RIPK2/JAK3/RARA/GATA3/IL23A	22
BP	GO:0030041	actin filament polymerization	57/4749	182/18670	0.04264	0.1987	0.1616	CDC42EP4/PLEKHG2/ICAM1/HCK/RAC1/CYFIP1/MSRB1/SNX9/CAPZB/GSN/CTTN/MTOR/MYADM/BAG4/CDC42EP1/TMOD2/TENM1/CAPG/CORO1B/WHAMMP3/ADD3/PFN2/HIP1R/ARPC1B/PAK3/PREX1/PICK1/TMSB4Y/SPTBN1/CORO1A/VASP/AIF1/TRIOBP/TWF2/DIAPH3/COTL1/SPTAN1/ARPC5/MKKS/CAPZA1/PRKCE/ACTR3B/KANK3/CORO7/TMSB15A/VILL/FER/ARF6/ARHGAP18/PSTPIP2/WHAMM/AP1AR/C15orf62/WAS/FMN1/ADD2/RAC3	57
BP	GO:0015748	organophosphate ester transport	35/4749	105/18670	0.04279	0.1987	0.1616	ABCC1/ABCG1/PCTP/MFSD2A/ATP11A/PRELID1/ATP8B4/SLC25A23/LDLR/ABCD1/PITPNA/C2CD2L/SLC25A25/PITPNM1/SLC35B2/ABCA1/KCNN4/STARD10/TMEM30A/ABCB4/SLC25A5/PLEKHA8/ATP10A/ATP8B3/SLC25A36/SLC33A1/ATP10D/SLC25A42/CETP/TNFAIP8L3/SLC25A4/GLTPD2/ATP11C/PLEKHA3/P2RX7	35
BP	GO:0032814	regulation of natural killer cell activation	13/4749	32/18670	0.04283	0.1987	0.1616	IL18/PRDM1/TOX/HAVCR2/AXL/PGLYRP3/HLA-E/MICA/RHBDD3/PIBF1/LAMP1/TYROBP/IL23A	13
BP	GO:0035587	purinergic receptor signaling pathway	13/4749	32/18670	0.04283	0.1987	0.1616	ACPP/ADORA2A/P2RY13/P2RX1/P2RY11/GPR34/P2RX6/P2RY10/GNAI2/P2RX5/P2RY1/PTAFR/P2RX7	13
BP	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	13/4749	32/18670	0.04283	0.1987	0.1616	SRC/AMBRA1/FLT3/VAV2/NOD2/CD19/FLT1/FPR2/AGAP2/PIK3R4/TNFAIP8L3/TGFB1/PDGFB	13
BP	GO:0060674	placenta blood vessel development	13/4749	32/18670	0.04283	0.1987	0.1616	FOSL1/PLCD3/ITGB8/VASH1/SOCS3/RBPJ/PKD2/SPINT1/ARID1A/GGNBP2/HS6ST1/FZD5/MAPK1	13
BP	GO:1902235	regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	13/4749	32/18670	0.04283	0.1987	0.1616	SERINC3/HSPA1A/PTPN1/PMAIP1/SYVN1/HERPUD1/DDIT3/PARK7/TXNDC12/BCL2L1/EIF2AK3/PDX1/SIRT1	13
BP	GO:1903955	positive regulation of protein targeting to mitochondrion	13/4749	32/18670	0.04283	0.1987	0.1616	USP36/SAE1/BAP1/PDCD5/HPS4/PINK1/RAC2/GSK3A/RHOU/UBL5/HSPA1L/FZD5/SREBF2	13
BP	GO:1905508	protein localization to microtubule organizing center	13/4749	32/18670	0.04283	0.1987	0.1616	STIL/AURKA/SPAG5/NUMA1/MARK4/PIBF1/CEP192/NSFL1C/CEP72/APC/PARD6A/MCPH1/NUP62	13
BP	GO:2000778	positive regulation of interleukin-6 secretion	13/4749	32/18670	0.04283	0.1987	0.1616	TWIST1/IL1B/TLR8/IL17A/LGALS9/HMGB1/TNF/LILRA2/AIF1/IL17RC/PAEP/LILRA5/F2R	13
BP	GO:0002064	epithelial cell development	64/4749	207/18670	0.04293	0.199	0.1619	MYO7A/IL1B/VEGFA/NOTCH1/CDKN1A/ICAM1/NTRK1/MYO1E/TP63/PRDM1/TYMS/ST14/TNF/PROC/COL18A1/TJP2/ADAMTSL4/MYADM/GPX1/SFN/PDE4D/SPDEF/RAB13/JAG1/SDC1/EZR/TBC1D20/WDPCP/RILPL2/TRIOBP/SCRIB/FNDC3A/FEM1B/WNT7A/PPP1R16B/SOX8/FOSL2/RAPGEF1/EPB41L5/DNASE1L2/SIDT2/STRC/ARNTL/VIM/GSK3A/RAPGEF2/SHROOM3/DACT2/BFSP2/ADIPOQ/ESR1/PTPRS/FASN/PLOD3/ARID4A/ACTA2/DLL1/ID1/C1GALT1/RARA/CDH5/PDGFB/BAD/ARHGEF26	64
BP	GO:0006354	DNA-templated transcription, elongation	37/4749	112/18670	0.04336	0.2009	0.1634	UBTF/IWS1/ENY2/CDK7/CCNT2/BRD4/EZH2/SUPT6H/RECQL5/RNF8/POLR2I/ERCC2/CCNK/ELP4/ZNF326/GTF2H2/POLR2C/GTF2H1/TAF1A/ZNRD1/EAF1/MLLT3/HTATSF1/MNAT1/TAF1D/ELL/POLR2J/EAF2/GTF2H5/NCBP2/TCEA2/POLR2A/POU4F1/EAPP/LDB1/POLR1B/RNF168	37
BP	GO:1903557	positive regulation of tumor necrosis factor superfamily cytokine production	30/4749	88/18670	0.04345	0.201	0.1635	TWIST1/CD86/TIRAP/CLEC7A/LGALS9/HMGB1/TNFRSF8/CYBB/TLR4/LILRA2/CARD9/CCR2/ARHGEF2/CCL3/CLU/HAVCR2/PTPRC/HLA-E/TLR2/NOD2/CYBA/LILRA5/IFNGR1/RIPK2/MAPKAPK2/TYROBP/FZD5/DDT/PTAFR/IL23A	30
BP	GO:0008089	anterograde axonal transport	18/4749	48/18670	0.04349	0.201	0.1635	KIF4A/KIF1C/BLOC1S6/BLOC1S1/CNIH2/BLOC1S4/AP3D1/DTNBP1/FMR1/AP3M2/SNAPIN/MAP1A/NEFL/AP3B2/SPG7/SYBU/MGARP/TERF2	18
BP	GO:0061647	histone H3-K9 modification	18/4749	48/18670	0.04349	0.201	0.1635	SETD7/SIRT6/SMARCB1/LMNA/CRTC2/NAP1L2/PRDM16/ZNF304/CHEK1/SETDB2/DMRTC2/SPHK2/ARID4A/KDM4C/ZNF451/SETDB1/GATA3/SIRT1	18
BP	GO:0051650	establishment of vesicle localization	87/4749	290/18670	0.04353	0.201	0.1636	MYO7A/ADORA2A/KIF23/SEC13/KIF1C/RIMS3/CDK5/BBS2/GORASP1/SEC24D/SYN1/MCFD2/NCS1/CHRNA5/F5/STX11/STX5/MYO5A/BLOC1S6/GRIPAP1/SEC16A/P2RX1/SYT4/SNAP47/HTR2A/BLOC1S1/CAMK2A/CNIH2/SNAP29/PFN2/HTT/SLC2A4/FYCO1/BLOC1S4/APBA2/STX1B/ANKRD28/PINK1/TBC1D20/CLASP2/ACTN4/DVL1/AP3D1/SCRIB/CEP19/STX19/MKKS/DRD1/TMED9/SNAP23/DTNBP1/RAB27A/WNT7A/PPFIA3/CNR1/ASIP/FMR1/GBF1/TMED10/SYT11/CTSZ/WDR11/AP3M2/ERC2/SNAPIN/NAPB/DNM1/STX2/DOC2B/TRAPPC4/PRKCB/P2RY1/RAB1A/CACNB2/FBXL20/KIAA1107/AP1AR/PPP6C/AP3B2/SV2A/PEF1/P2RX7/SYBU/PPP6R1/RAB1B/TRIM9/USO1	87
BP	GO:0035967	cellular response to topologically incorrect protein	51/4749	161/18670	0.04367	0.2013	0.1638	HSPA2/ATP6V0D1/ATF3/HSPA5/CREB3L2/SDF2L1/SERP2/HSPA1A/DERL1/BAX/TPP1/PTPN1/ZBTB17/LMNA/SYVN1/POMT2/HSPA9/VCP/DNAJB12/HERPUD1/ATF4/ASNS/CTH/CCL2/EXTL2/PARP16/BAK1/DDIT3/CREBRF/SDF2/BAG3/FICD/GSK3A/HSPA6/KLHDC3/YIF1A/DDX11/EIF2AK3/ERN1/SERP1/CANX/HSPA1L/RNF121/HSPA14/MBTPS2/PPP1R15A/HERPUD2/TMEM33/CCND1/SHC1/UBE2W	51
BP	GO:0061982	meiosis I cell cycle process	39/4749	119/18670	0.04377	0.2013	0.1638	ESPL1/TOP2A/AURKA/HSPA2/TRIP13/PTTG1/CDC25A/RAD54L/SYCE3/SLC2A8/MSH6/BRCA2/UBE2B/PLK1/CDC25C/RAD51/TDRD9/CKS2/FBXO5/DMC1/UBB/MND1/CCNE2/TERF1/HELQ/REC8/STAG3/EME1/KLHDC3/SYCE2/UBR2/DMRTC2/ANKRD31/ATM/MLH3/RNF212/CDC25B/ERCC1/RAD54B	39
BP	GO:0010769	regulation of cell morphogenesis involved in differentiation	90/4749	301/18670	0.0439	0.2013	0.1638	SKIL/VEGFA/MAP6/NTRK2/NEDD9/SIPA1L1/SRF/RAC1/PLXNB2/CYFIP1/LZTS1/YWHAH/CDK5/CORO1C/SPP1/GORASP1/SEMA4C/PLXNB1/TNFRSF12A/LRP8/SEMA7A/ZSWIM5/CTTN/CUX1/MYADM/ZFYVE27/SEMA3G/TIAM1/SEMA6C/AMIGO1/DOCK1/NTRK3/SDC2/PLXNA1/PAK1/LIMS1/SEMA6B/DOCK5/ARHGAP35/PAK3/PREX1/FBXO31/LRP4/FGF13/ARHGAP4/TRIOBP/TWF2/L1CAM/CFL1/PLXND1/ACTN4/S100A10/LRP1/LIMK1/THY1/ZSWIM6/TTL/WNT7A/UNC13D/STK25/FMR1/UBE3A/CRK/ARHGAP33/SEMA3B/IST1/SEMA5B/BRSK2/RAPGEF2/CHN1/PARP6/PTPRS/CHRNA3/SEMA4D/C1QBP/LRRC4C/ARHGDIA/NEFL/AP1AR/ID1/RUFY3/SEMA5A/CDC42/HAS2/RTN4R/ADNP/TRPC5/GDI1/ILK/RAC3	90
BP	GO:0044550	secondary metabolite biosynthetic process	12/4749	29/18670	0.04401	0.2013	0.1638	TRPC1/CTNS/MPST/MYO5A/CTH/SP1/ASIP/OCA2/BDH2/RAPGEF2/DDT/TYRP1	12
BP	GO:0046134	pyrimidine nucleoside biosynthetic process	12/4749	29/18670	0.04401	0.2013	0.1638	TYMP/DHODH/TK1/DTYMK/NME4/UPRT/NME3/CMPK1/CTPS2/UCK2/NME9/NME2	12
BP	GO:0071280	cellular response to copper ion	12/4749	29/18670	0.04401	0.2013	0.1638	MAP1LC3A/MT1E/MT2A/AQP2/MT1X/MT1H/MT1G/PRNP/MT1A/MT1B/MT1M/MT1F	12
BP	GO:0072538	T-helper 17 type immune response	12/4749	29/18670	0.04401	0.2013	0.1638	NLRP3/BATF/IRF4/FOXP3/STAT3/SMAD7/LY9/RORC/IL12RB1/IL27RA/ZC3H12A/IL23A	12
BP	GO:2000171	negative regulation of dendrite development	12/4749	29/18670	0.04401	0.2013	0.1638	BCL11A/YWHAH/GORASP1/PLK2/CARM1/UBE3A/GSK3A/RAPGEF2/PTPRS/ARF6/ID1/TRPC5	12
BP	GO:0051924	regulation of calcium ion transport	77/4749	254/18670	0.04414	0.2013	0.1638	GEM/ICAM1/ADORA2A/HSPA2/PTPN6/CCR1/SESTD1/ANXA2P2/LGALS3/YWHAE/PML/TSPAN13/JSRP1/BAX/CXCL10/TRPC1/LILRA2/ANXA2/HOMER2/TSPO/MYO5A/HCRT/REM1/P2RX1/HOMER1/PDE4D/ATP2A1/CCL3/CAMK2A/KCNE3/PDE4B/SRI/CD33/PKD2/HTT/CCL2/GPR35/ATP1B1/CASR/GSTO1/REM2/CORO1A/STAC3/CXCL9/BAK1/DRD1/LILRB2/FKBP1A/STAC/THY1/CD19/SUMO1/GNAI2/NTSR1/FMR1/CAMK2G/PRKCE/GRIN3B/CYBA/LILRA5/LACRT/IL13/CAMK2D/P2RX5/PRNP/F2R/EPB41/AHNAK/SPHK2/CACNB2/TMC2/EHD3/FFAR1/TGFB1/PDGFB/P2RX7/FYN	77
BP	GO:0006266	DNA ligation	8/4749	17/18670	0.04419	0.2013	0.1638	TOP2A/HMGB1/RAD51/XRCC6/TFIP11/APLF/XRCC1/MGMT	8
BP	GO:0006750	glutathione biosynthetic process	8/4749	17/18670	0.04419	0.2013	0.1638	CHAC1/CHAC2/GGT1/OPLAH/MGST2/GCLC/GGT7/GSS	8
BP	GO:0015868	purine ribonucleotide transport	8/4749	17/18670	0.04419	0.2013	0.1638	SLC25A23/ABCD1/SLC25A25/SLC35B2/SLC25A5/SLC33A1/SLC25A42/SLC25A4	8
BP	GO:0016254	preassembly of GPI anchor in ER membrane	8/4749	17/18670	0.04419	0.2013	0.1638	PIGH/DPM2/PIGQ/PIGC/PIGW/PIGM/PIGA/PIGG	8
BP	GO:0030322	stabilization of membrane potential	8/4749	17/18670	0.04419	0.2013	0.1638	KCNK5/KCNK6/KCNN4/KCNK7/KCNK1/KCNK15/KCNK18/KCNK2	8
BP	GO:0033599	regulation of mammary gland epithelial cell proliferation	8/4749	17/18670	0.04419	0.2013	0.1638	IQGAP3/BRCA2/BAX/GPX1/KDM5B/ZNF703/CCND1/GATA3	8
BP	GO:0035518	histone H2A monoubiquitination	8/4749	17/18670	0.04419	0.2013	0.1638	DDB2/RYBP/BCOR/PCGF6/PCGF1/PCGF5/BMI1/RNF168	8
BP	GO:0070131	positive regulation of mitochondrial translation	8/4749	17/18670	0.04419	0.2013	0.1638	NSUN4/FASTKD2/COA3/TRUB2/FASTKD3/TRMT10C/C1QBP/NGRN	8
BP	GO:2000001	regulation of DNA damage checkpoint	8/4749	17/18670	0.04419	0.2013	0.1638	CRY1/RFWD3/FEM1B/WDR76/ETAA1/CHEK2/CUL4A/FBXO4	8
BP	GO:2001267	regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	8/4749	17/18670	0.04419	0.2013	0.1638	PLAUR/MMP9/LGALS9/GSN/BAX/FAS/PARK7/ST18	8
BP	GO:0051196	regulation of coenzyme metabolic process	32/4749	95/18670	0.04453	0.2023	0.1646	PDPR/SEC13/TREX1/PFKFB3/PGAM1/CBFA2T3/SIRT6/NUP98/PPTC7/ENTPD5/STAT3/HTR2A/PFKFB4/NUP153/DDIT4/PFKFB2/NUP88/PRKAG2/POM121C/NUP205/RAE1/NUP50/INSR/NUPR1/NUP93/NUP35/AAAS/GSTZ1/NUP62/P2RX7/SEH1L/NCOR1	32
BP	GO:2000060	positive regulation of ubiquitin-dependent protein catabolic process	32/4749	95/18670	0.04453	0.2023	0.1646	RNF144A/AURKA/TRIB1/CBFA2T3/HSPA1A/PLK2/PLK1/DET1/SMAD7/VCP/CLU/MAGEF1/HERPUD1/SGTA/SMURF1/PIAS1/BCAP31/DVL1/GBA/SUMO1/RNF19B/RAD23A/USP5/GSK3A/UBQLN2/SIRT2/ZFAND2A/RNF139/GCLC/PSMD10/DNAJB2/TRIB3	32
BP	GO:0043407	negative regulation of MAP kinase activity	27/4749	78/18670	0.04456	0.2023	0.1646	IL1B/DUSP10/DUSP4/PTPN6/DUSP6/SPRED2/DNAJA1/PPP2R1A/PTPN1/PDCD4/SORL1/DUSP5/IRAK3/DUSP16/PPP2CA/GBA/DEFB114/DUSP18/SFRP1/ADIPOQ/AIDA/STK38/DUSP14/ZNF675/UCHL1/NUP62/DUSP1	27
BP	GO:0001556	oocyte maturation	11/4749	26/18670	0.04491	0.2023	0.1646	AURKA/TRIP13/PPP2R1A/BRCA2/CCNB1/FBXO5/PABPC1L/DMC1/REC8/SIRT2/CDC25B	11
BP	GO:0007020	microtubule nucleation	11/4749	26/18670	0.04491	0.2023	0.1646	HSPA1A/CENPJ/RANGRF/TUBGCP2/CLASP2/TUBG2/CEP192/TUBG1/SLAIN2/TUBGCP5/TUBGCP3	11
BP	GO:0022011	myelination in peripheral nervous system	11/4749	26/18670	0.04491	0.2023	0.1646	NTRK2/SKI/FA2H/NTRK3/MPP5/NDRG1/ADAM22/POU3F1/SIRT2/DICER1/ILK	11
BP	GO:0032292	peripheral nervous system axon ensheathment	11/4749	26/18670	0.04491	0.2023	0.1646	NTRK2/SKI/FA2H/NTRK3/MPP5/NDRG1/ADAM22/POU3F1/SIRT2/DICER1/ILK	11
BP	GO:0034114	regulation of heterotypic cell-cell adhesion	11/4749	26/18670	0.04491	0.2023	0.1646	IL1B/WNK1/IL10/KLF4/IL1RN/TNF/MYADM/FLOT1/THY1/CD44/ADIPOQ	11
BP	GO:0034204	lipid translocation	11/4749	26/18670	0.04491	0.2023	0.1646	ABCC1/ATP11A/ATP8B4/ABCA1/KCNN4/TMEM30A/ABCB4/ATP10A/ATP8B3/ATP10D/ATP11C	11
BP	GO:0048753	pigment granule organization	11/4749	26/18670	0.04491	0.2023	0.1646	BLOC1S6/RAB32/BLOC1S1/BLOC1S4/HPS4/AP3D1/DTNBP1/ASIP/RAB38/SNAPIN/TYRP1	11
BP	GO:0072539	T-helper 17 cell differentiation	11/4749	26/18670	0.04491	0.2023	0.1646	NLRP3/BATF/IRF4/FOXP3/STAT3/SMAD7/LY9/RORC/IL12RB1/ZC3H12A/IL23A	11
BP	GO:0032722	positive regulation of chemokine production	21/4749	58/18670	0.04496	0.2023	0.1646	EGR1/TWIST1/IL1B/CSF1R/TIRAP/CLEC7A/LGALS9/TNF/TLR4/IL4R/FFAR2/HMOX1/HAVCR2/CD74/FFAR3/AIF1/TLR2/LRP1/IL7/ADIPOQ/RIPK2	21
BP	GO:0019915	lipid storage	24/4749	68/18670	0.04516	0.2023	0.1646	IL1B/PPARG/ABCG1/TNF/GM2A/FFAR2/FITM2/FITM1/CRY1/ABCA1/ACVR1C/MEST/NFKBIA/PLIN2/ZC3H12A/SQLE/BSCL2/DGAT2/ACACB/HEXB/TTC39B/PPARD/SREBF2/SIRT1	24
BP	GO:0006473	protein acetylation	63/4749	204/18670	0.04525	0.2023	0.1646	TWIST1/LIF/IL1B/GTF3C4/IRF4/ESCO2/SPI1/CAMK1/DPF3/BRCA2/PHF10/FOXP3/SMARCB1/CRTC2/ING3/NAP1L2/ING5/KANSL3/IWS1/ARRB1/MORF4L2/KANSL1L/BLOC1S1/KAT2A/ACTL6A/FOXO1/MDH2/TAF1L/YEATS4/SUPT3H/DSCC1/TAF9B/MUC1/TAF6L/TAF10/NAA16/PARK7/CHEK1/MCRS1/NAT9/ARNTL/LACRT/BRPF3/TAF7/KAT6B/POR/AANAT/DPF1/TADA2A/NUPR1/SPHK2/CTBP1/TGFB1/ZNF451/TRIM16/LDB1/GATA3/CPA4/TADA1/HINT2/KAT6A/MAGEA2B/SIRT1	63
BP	GO:1902905	positive regulation of supramolecular fiber organization	63/4749	204/18670	0.04525	0.2023	0.1646	CDC42EP4/SDC4/ICAM1/FES/HCK/RAC1/CYFIP1/NF2/FHOD1/SNX9/GSN/HSPA1A/CTTN/MTOR/GPX1/BAG4/PSRC1/CDC42EP1/SWAP70/TENM1/ARHGEF5/NUMA1/CORO1B/CLU/PDXP/TGFB3/WHAMMP3/PAK1/PFN2/RPS3/HIP1R/ARPC1B/TERF1/PICK1/CORO1A/CD47/VASP/LIMCH1/CFL1/S100A10/ARPC5/LIMK1/SH3PXD2B/PRKCE/ACTR3B/WDR1/SFRP1/FER/BMP10/ARF6/TPM1/ARL2/SORBS3/WHAMM/AP1AR/SLAIN2/ID1/C15orf62/SEMA5A/CDC42/WAS/FMN1/RAC3	63
BP	GO:0032495	response to muramyl dipeptide	9/4749	20/18670	0.04525	0.2023	0.1646	NOTCH1/IRF5/CARD9/ARHGEF2/JAG1/NOD2/NFKBIA/VIM/RIPK2	9
BP	GO:0033617	mitochondrial respiratory chain complex IV assembly	9/4749	20/18670	0.04525	0.2023	0.1646	SCO2/COX17/PET117/COX18/COA3/SCO1/FASTKD3/COA5/COA4	9
BP	GO:0045019	negative regulation of nitric oxide biosynthetic process	9/4749	20/18670	0.04525	0.2023	0.1646	IL10/ACP5/PTGIS/SIRPA/TSPO/ATP2B4/ZC3H12A/CD34/KHSRP	9
BP	GO:0050860	negative regulation of T cell receptor signaling pathway	9/4749	20/18670	0.04525	0.2023	0.1646	PTPN6/LGALS3/CEACAM1/BTN2A2/LILRB4/EZR/DUSP22/THY1/PRNP	9
BP	GO:0070262	peptidyl-serine dephosphorylation	9/4749	20/18670	0.04525	0.2023	0.1646	YWHAE/PPP2R1A/PPTC7/SWAP70/PPP2CA/PPP1R16B/PPP5C/PPP1R15A/DUSP1	9
BP	GO:0071397	cellular response to cholesterol	9/4749	20/18670	0.04525	0.2023	0.1646	PTCH1/LRP8/GRAMD1C/GRAMD1B/ABCA1/LRP6/OSBPL7/GRAMD1A/CYP7A1	9
BP	GO:0097062	dendritic spine maintenance	9/4749	20/18670	0.04525	0.2023	0.1646	ITGA3/CTTN/HOMER1/IGF1R/PICK1/TANC1/PRNP/INSR/FYN	9
BP	GO:1904406	negative regulation of nitric oxide metabolic process	9/4749	20/18670	0.04525	0.2023	0.1646	IL10/ACP5/PTGIS/SIRPA/TSPO/ATP2B4/ZC3H12A/CD34/KHSRP	9
BP	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	34/4749	102/18670	0.04535	0.2023	0.1646	KIF2C/KIF4A/KIF15/KIF23/SEC13/RACGAP1/KIF18A/IFI30/SEC24D/CAPZB/HLA-DQB2/KIF11/HLA-DMA/KLC1/CENPE/KIF4B/CD74/CTSF/DCTN5/HLA-DPA1/HLA-DRA/AP1S1/AP2S1/CTSD/LAG3/CAPZA1/KIF3C/HLA-DMB/HLA-DQA2/ACTR1A/CANX/HLA-DPB1/TRAF6/HLA-DRB1	34
BP	GO:0032703	negative regulation of interleukin-2 production	10/4749	23/18670	0.04539	0.2023	0.1646	ZFP36/FOXP3/HOMER2/HAVCR2/PTPRC/EZR/LAG3/CD34/PRNP/GATA3	10
BP	GO:0042451	purine nucleoside biosynthetic process	10/4749	23/18670	0.04539	0.2023	0.1646	HPRT1/NME4/NME3/MTAP/APRT/IMPDH1/GUK1/NT5E/NME9/NME2	10
BP	GO:0046129	purine ribonucleoside biosynthetic process	10/4749	23/18670	0.04539	0.2023	0.1646	HPRT1/NME4/NME3/MTAP/APRT/IMPDH1/GUK1/NT5E/NME9/NME2	10
BP	GO:0051882	mitochondrial depolarization	10/4749	23/18670	0.04539	0.2023	0.1646	MLLT11/ABCD1/TSPO/SRC/IFI6/PPP2R3C/CCK/FZD9/GCLC/P2RX7	10
BP	GO:0070841	inclusion body assembly	10/4749	23/18670	0.04539	0.2023	0.1646	HSPA2/UBD/HSPA1A/SORL1/VCP/CLU/BAG3/DNAJB6/DNAJB2/PSMC5	10
BP	GO:0071305	cellular response to vitamin D	10/4749	23/18670	0.04539	0.2023	0.1646	VDR/KANK2/FES/GDAP1/PIM1/PHEX/CASR/CYP27B1/BGLAP/SFRP1	10
BP	GO:1903429	regulation of cell maturation	10/4749	23/18670	0.04539	0.2023	0.1646	KIF14/AURKA/BCL11A/CLEC7A/PPP2R1A/MTOR/TBX6/PAEP/SIRT2/RAC3	10
BP	GO:0016574	histone ubiquitination	17/4749	45/18670	0.04566	0.2034	0.1655	UBE2A/UHRF1/DDB2/UBE2B/RYBP/DTX3L/UBE2N/BCOR/RNF40/CBX8/RNF8/PCGF6/PCGF1/PCGF5/UBR2/BMI1/RNF168	17
BP	GO:0006661	phosphatidylinositol biosynthetic process	38/4749	116/18670	0.04636	0.2064	0.1679	PTPN13/PDGFA/SBF1/MTMR3/PLEKHA1/INPP4A/HTR2A/PIGK/SH3YL1/PIGH/PIK3R5/PITPNM1/PIKFYVE/DPM2/MTMR9/PLEKHA2/PIP5K1B/PIGQ/PI4K2A/PIGO/FPR2/PLEKHA8/AGAP2/PIGC/MTMR14/PIGW/PIK3C3/PIP4K2A/PIK3R4/PIGM/PIGA/PIP4K2B/ATM/PIP5K1A/PLEKHA3/PDGFB/PIGG/PIGT	38
BP	GO:0006644	phospholipid metabolic process	125/4749	430/18670	0.04656	0.2071	0.1685	TTC7A/MBOAT7/PTPN13/SGMS1/CSF1R/KLF4/PDGFA/CPNE7/DOLPP1/SBF1/PCTP/MFSD2A/SGMS2/MTMR3/SOCS2/SERINC3/AGPAT3/ABHD16A/PLBD1/TTC7B/LDLR/AGPAT2/THEM5/PLEKHA1/PMVK/GDPD3/FDPS/SRC/FITM2/SOCS3/NKX2-1/DGKZ/INPP4A/FABP5/PLA2G12A/HTR2A/PIGK/FITM1/LPCAT2/SH3YL1/TMEM86B/PIGH/TMEM150A/AMBRA1/PIK3R5/PITPNM1/FLT3/GDPD1/PIKFYVE/SGPP1/DPM2/VAV2/MTMR9/IMPA2/PLEKHA2/LPCAT3/PIP5K1B/ACP6/PIGQ/PI4K2A/PIGO/NOD2/STARD10/SLA2/CD19/FLT1/GPX4/FPR2/PLEKHA8/AGAP2/LPCAT4/INPP1/PIGC/RAB38/PTPMT1/MTMR14/PLA2G15/PNPLA6/FAM126B/PRDX6/PIGW/PIK3C3/IP6K1/PLA2G2A/GDE1/PLA2G2C/TAMM41/LCLAT1/CETP/SPHK2/HEXB/PIP4K2A/PIK3R4/TNFAIP8L3/PIGM/PTDSS1/PIGA/IP6K2/AGK/PIP4K2B/PLA2G5/ATM/PPARD/TAZ/DOLK/PIP5K1A/IDI2/GPCPD1/PLCB1/TGFB1/ALDH5A1/GALR2/GPAT2/HADHB/PLB1/MBOAT1/PLEKHA3/PDGFB/IP6K3/PIGG/LPIN1/PIGT/CRLS1/PGS1/SLC44A1	125
BP	GO:0050770	regulation of axonogenesis	57/4749	183/18670	0.04699	0.2089	0.1699	SKIL/VEGFA/MAP6/NTRK2/SIPA1L1/SRF/PLXNB2/CYFIP1/CDK5/SPP1/SEMA4C/PLXNB1/TNFRSF12A/SEMA7A/ZSWIM5/CTTN/ZFYVE27/SEMA3G/TIAM1/SEMA6C/AMIGO1/NTRK3/PLXNA1/PAK1/SEMA6B/ARHGAP35/PAK3/LRP4/FGF13/ARHGAP4/TWF2/L1CAM/PLXND1/LRP1/LIMK1/THY1/ZSWIM6/TTL/WNT7A/STK25/SEMA3B/IST1/SEMA5B/BRSK2/CHN1/PTPRS/SEMA4D/LRRC4C/ARHGDIA/NEFL/RUFY3/SEMA5A/RTN4R/ADNP/TRPC5/GDI1/ILK	57
BP	GO:0007623	circadian rhythm	64/4749	208/18670	0.04701	0.2089	0.1699	EGR1/EGR3/RELB/CDK1/CSF2/PPARG/TOP2A/ADORA2A/NTRK2/NTRK1/PSPC1/SFPQ/ARNTL2/PML/TYMS/ATF5/PPP1CB/USP9X/SERPINE1/DBP/MTOR/NKX2-1/NTRK3/CRY1/ATF4/PER2/ZFHX3/CRTC1/BHLHE40/RORC/NAMPT/KLF9/EZH2/TIMELESS/RBM4B/KDM8/JUN/UBE3A/FBXW11/MYBBP1A/PHLPP1/ARNTL/TPH1/KLF10/SIAH2/NPS/NDUFA9/BTRC/GHRL/BHLHE41/ADIPOQ/CPT1A/PASD1/KDM5A/AANAT/GNAQ/MTA1/PER3/ID1/ATG7/CLDN4/NCOR1/MC3R/SIRT1	64
BP	GO:0015914	phospholipid transport	26/4749	75/18670	0.04722	0.2096	0.1705	ABCC1/ABCG1/PCTP/MFSD2A/ATP11A/PRELID1/ATP8B4/LDLR/PITPNA/C2CD2L/PITPNM1/ABCA1/KCNN4/STARD10/TMEM30A/ABCB4/PLEKHA8/ATP10A/ATP8B3/ATP10D/CETP/TNFAIP8L3/GLTPD2/ATP11C/PLEKHA3/P2RX7	26
BP	GO:0002011	morphogenesis of an epithelial sheet	20/4749	55/18670	0.04747	0.2106	0.1713	HBEGF/NOTCH1/COL5A1/SRF/CEACAM1/MTOR/MMP12/ARHGAP35/JAG1/MPP5/CLASP2/DVL1/WNT7A/CD44/HOXB2/CD151/SOX11/DDR1/LRP6/LIN7C	20
BP	GO:0002548	monocyte chemotaxis	23/4749	65/18670	0.04781	0.2119	0.1724	CCL20/CCL3L3/CCL22/CCR1/LGALS3/HMGB1/CXCL10/SERPINE1/CCR2/CCL3/CCL2/CCL17/RPS19/AIF1/CCL18/FLT1/FPR2/CCL23/TNFSF11/CCL7/CCL15/PDGFB/DUSP1	23
BP	GO:0006509	membrane protein ectodomain proteolysis	16/4749	42/18670	0.0479	0.212	0.1725	IL1B/FURIN/IL10/TIMP4/TIMP2/ADAM19/SNX9/TNF/TIMP1/SNX33/ERAP1/MYH9/TNFRSF1B/TIMP3/ADAM9/P2RX7	16
BP	GO:1903146	regulation of autophagy of mitochondrion	16/4749	42/18670	0.0479	0.212	0.1725	BNIP3L/HK2/CTTN/TSPO/USP36/ATP13A2/HTT/SMURF1/PINK1/GBA/VDAC1/PARK7/GSK3A/VPS13D/FZD5/SREBF2	16
BP	GO:0030833	regulation of actin filament polymerization	51/4749	162/18670	0.04842	0.2139	0.174	CDC42EP4/PLEKHG2/ICAM1/HCK/CYFIP1/SNX9/CAPZB/GSN/CTTN/MTOR/MYADM/BAG4/CDC42EP1/TMOD2/TENM1/CAPG/CORO1B/WHAMMP3/ADD3/PFN2/HIP1R/ARPC1B/PAK3/PREX1/PICK1/TMSB4Y/SPTBN1/CORO1A/VASP/TRIOBP/TWF2/COTL1/SPTAN1/ARPC5/MKKS/CAPZA1/PRKCE/ACTR3B/KANK3/TMSB15A/VILL/FER/ARF6/ARHGAP18/WHAMM/AP1AR/C15orf62/WAS/FMN1/ADD2/RAC3	51
BP	GO:0031960	response to corticosteroid	51/4749	162/18670	0.04842	0.2139	0.174	NOTCH1/CDKN1A/ICAM1/CASP9/FOSL1/IL10/IL1RN/GLB1/FOSB/TYMS/EIF4EBP1/TNF/ZFP36/CYBB/NR3C1/SRC/PPARGC1B/CFLAR/PAM/NTRK3/FLT3/FOXO1/ZFP36L2/SDC1/DDIT4/AIF1/KLF9/GBA/ARG1/CREBRF/IL22/CYBA/BGLAP/ADM/HSD3B2/ALDH3A1/ADIPOQ/AANAT/ZFP36L1/SOX30/AKAP13/NEFL/ABCA3/FOS/TGFB1/CCND1/ADAM9/PTAFR/PDX1/BAD/DUSP1	51
BP	GO:0046883	regulation of hormone secretion	80/4749	266/18670	0.04843	0.2139	0.174	LIF/IL1B/ADORA2A/RAC1/PIM3/RAB11FIP1/SLC16A1/NMB/SPP1/TNF/ADRA2B/SCG5/BLK/FFAR2/TIAM1/ABAT/ARRB1/GNAS/ENY2/C2CD2L/SRI/CRY1/ENHO/PER2/CCKAR/FFAR3/CASR/TCF7L2/KDM5B/PRKCA/TRPM4/NADK/ANXA5/OXCT1/PFKFB2/PSMD9/LRP1/OSM/CACNA2D2/SIRT3/ILDR1/CNR1/C1QTNF3/TFAP2B/RAB11FIP3/ACVR1C/SLC25A5/PRKCE/TACR2/SIDT2/LRP5L/SOX11/ARNTL/GLUD1/BRSK2/SFRP1/GHRL/KCNG2/ADIPOQ/CPT1A/ARL2BP/RAB11FIP5/SERP1/DOC2B/CHRNA3/P2RY1/SLC25A4/PFKL/TNFSF11/ARL2/NPFF/PPARD/SLC9B2/FFAR1/TMF1/NDUFAF2/PDX1/GIPR/SYBU/BAD	80
BP	GO:0065004	protein-DNA complex assembly	75/4749	248/18670	0.04877	0.2153	0.1752	CENPF/CENPA/HJURP/ASF1B/CDT1/CENPM/CHAF1A/MCM4/MCM5/CHAF1B/GMNN/THRA/CENPW/DDB2/HMGB1/UBTF/SPTY2D1/NASP/WNT10B/RAD51/SMARCB1/NAP1L2/MCM2/CENPE/CDC45/CENPT/DMC1/UBB/CENPO/RPS27A/MCM7/BRF2/TERF1/CDK7/SMARCA4/PIAS1/RAD23B/UBA52/NAP1L3/CENPI/TAF6L/CENPP/CENPN/UBN1/ERCC5/MCM3/ERCC2/TAF11/GTF2H2/TSPYL1/GTF2H1/HELLS/OIP5/TSPYL4/TAF7/KAT6B/ESR1/TAF6/BDP1/MNAT1/CETN2/CENPV/BAZ2A/RAD52/NAP1L5/GTF2H5/XPA/SENP6/POGZ/CUL4A/TRAPPC12/ASF1A/PSMC5/KAT6A/CENPK	75
BP	GO:0008643	carbohydrate transport	47/4749	148/18670	0.04909	0.2166	0.1762	IL1B/SLC35A2/NR4A3/MFSD2A/TNF/SIRT6/SLC2A8/HK2/PEA15/SLC2A3/SLC5A3/SLC35B1/CLIP3/FABP5/PLS1/SLC35D2/SLC2A4/SLC35D1/RSC1A1/AQP2/EZR/PRKCI/ADIPOR2/SLC45A3/DRD1/SLC26A6/PRKAG2/SLC35C1/MFSD2B/GSK3A/CREBL2/SLC2A11/BRAF/ADIPOQ/SLC2A14/SLC23A2/SLC5A4/PRKCB/SLC37A3/AQP7/INSR/SLC35B4/PPBP/PPARD/MFSD12/SESN2/TRIB3	47
BP	GO:1903052	positive regulation of proteolysis involved in cellular protein catabolic process	39/4749	120/18670	0.04938	0.2177	0.1771	RNF144A/AURKA/TRIB1/CBFA2T3/HSPA1A/PLK2/ECSCR/PLK1/DET1/SMAD7/VCP/CLU/MAGEF1/HERPUD1/RNF40/SGTA/SMURF1/PIAS1/BCAP31/DVL1/GBA/SUMO1/RNF19B/FMR1/RAD23A/EDEM2/USP5/GSK3A/UBQLN2/BAG2/SIRT2/ZFAND2A/RNF139/GCLC/NUPR1/OSBPL7/PSMD10/DNAJB2/TRIB3	39
BP	GO:0045727	positive regulation of translation	41/4749	127/18670	0.04948	0.218	0.1773	ITGA2/LARP4/BCL3/TNF/MTOR/POLDIP3/RPL5/RPL26/CTIF/NSUN4/CIRBP/PINK1/FASTKD2/CNBP/COA3/RPS9/RXRA/TRUB2/FMR1/ERBB2/RPS4X/VIM/UPF3A/ELAVL1/YTHDF3/EIF2S3/FASTKD3/ZCCHC4/MIF4GD/UHMK1/PRR16/TRMT10C/SERP1/C1QBP/PPP1R15A/NGRN/EIF3E/RBM3/GUF1/MAPK1/PTAFR	41
BP	GO:1905330	regulation of morphogenesis of an epithelium	56/4749	180/18670	0.04959	0.2183	0.1776	LIF/SAPCD2/VEGFA/PDGFA/RAC1/VANGL1/TNF/SIRT6/CXCL10/MTOR/ITGAX/RNF207/ETV5/NKD1/TIAM1/CTHRC1/PSMD8/DVL3/PSMD1/PSMD2/FZD6/PTK7/PSMF1/HOXB7/SMURF1/CLASP2/DVL1/PSMD9/AP2S1/PSMA5/RXRA/WNT7A/SOX8/PSMB7/PSMD5/PSME2/SFRP1/RSPO3/PSMB5/ESR1/MLLT3/PSMB4/PSMA3/STAT1/MED12/PARD6A/FZD5/PSMD10/TGFB1/CDC42/PSMB1/PSMD7/PSMB3/PSMC5/GATA3/PSMD11	56
BP	GO:0006635	fatty acid beta-oxidation	25/4749	72/18670	0.05005	0.2198	0.1788	TWIST1/MTOR/ABCD1/MECR/ABCD2/SLC27A2/MCAT/ACOX2/TYSND1/ACOT8/CNR1/AMACR/ETFA/PEX2/BDH2/ADIPOQ/CPT1A/ACACB/ETFB/ACAD11/ECI1/PPARD/HADHB/SESN2/DECR2	25
BP	GO:1902036	regulation of hematopoietic stem cell differentiation	25/4749	72/18670	0.05005	0.2198	0.1788	TP73/CBFB/HSPA9/PSMD8/PSMD1/PSMD2/PSMF1/PSMD9/PSMA5/OSM/PSMB7/PSMD5/YAP1/PSME2/PSMB5/PSMB4/PSMA3/PSMD10/PSMB1/PSMD7/PSMB3/PSMC5/LDB1/GATA3/PSMD11	25
BP	GO:0032602	chemokine production	30/4749	89/18670	0.05006	0.2198	0.1788	EGR1/TWIST1/IL1B/IL18/CSF1R/IL10/KLF4/SIRPA/TIRAP/TNFSF4/CLEC7A/LGALS9/TNF/TLR4/IL4R/FFAR2/HMOX1/HAVCR2/CD74/FFAR3/SIGIRR/AIF1/TLR2/LRP1/C1QTNF3/IL7/S100A8/ADIPOQ/RIPK2/ZFPM1	30
BP	GO:0070126	mitochondrial translational termination	30/4749	89/18670	0.05006	0.2198	0.1788	MRPL37/MRPL28/MRPL51/MRPS36/MRPL22/MRPL18/MRPS5/MRPS18C/MRPS11/MRPS6/MRPL20/MRPL50/MRPL36/MRPS2/MRPL35/MRPL27/MRPL15/MRPS25/MRPL34/MRPS14/MRPL13/PTCD3/GADD45GIP1/MRPL10/MRPL54/DAP3/MRPL2/MRPL39/MRPL43/MRPL48	30
BP	GO:1901998	toxin transport	15/4749	39/18670	0.05017	0.22	0.1789	ABCG1/DNAJA1/HSPA5/CRTC2/TRIP4/SLC22A3/CCT5/ANTXR2/ARID1A/DNM1/RAB40B/LRP6/DNAJC17/RAB28/CCT3	15
BP	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	15/4749	39/18670	0.05017	0.22	0.1789	ICAM1/FAIM2/RFFL/SERPINE1/PEA15/GPX1/HMOX1/ARHGEF2/CFLAR/FAS/TNFRSF10B/PARK7/BCL2L1/TRAF2/TNFSF10	15
BP	GO:0071478	cellular response to radiation	59/4749	191/18670	0.05098	0.2234	0.1817	EGR1/AURKB/PBK/CDKN1A/CASP9/TREX1/CDC25A/DDB2/HSPA5/CRIP1/BAX/GADD45A/RAD51/HYAL3/RAD51AP1/RPL26/TP53BP1/BMF/CRY1/ATF4/XRCC6/N4BP1/GUCA1C/NMT1/NAMPT/FIGNL1/BAK1/TANK/TP53INP1/CNGA1/GPR52/ELK1/FMR1/CHEK1/ECT2/RBL2/BCL2L1/CYBA/YAP1/IFI16/SFRP1/ATR/CHEK2/FNTB/GTF2H5/CAMKMT/XPA/ATM/NUCKS1/WRN/TGFB1/NET1/MGMT/GATA3/PDE6B/ERCC1/FBXO4/RAD9A/SIRT1	59
BP	GO:0016050	vesicle organization	96/4749	325/18670	0.05125	0.2244	0.1826	MYO7A/SDC4/SQSTM1/SEC13/ZNF385A/ANXA2P2/CORO1C/GORASP1/SEC24D/CHMP2B/RFX2/MCFD2/ANXA2/F5/SNF8/STX11/STX5/BLOC1S6/SEC16A/FBXO5/SYT4/RAB32/SNAP47/SDCBP/BLOC1S1/STAM/VPS33B/CNIH2/CCDC136/SNAP29/SLC2A4/BLOC1S4/STX1B/HPS4/SDC1/ANKRD28/TBC1D20/CORO1A/PRKCI/ABCA1/AP3D1/S100A10/STX19/INSIG1/PI4K2A/TMED9/SNAP23/DTNBP1/HGS/TMEM175/STX12/TAP1/RAB27A/HOOK2/ASIP/GBF1/SNX11/SNX19/TMED10/VAMP3/CTSZ/SNX33/STX16/RAB38/IST1/SRGN/UVRAG/SNAPIN/CD2AP/PIK3C3/VTI1B/DNM1/CHMP1A/CD34/EEA1/F2R/STX2/DOC2B/TRAPPC4/CHMP2A/RAB1A/RAB34/VPS39/PPP6C/ALS2CL/TYRP1/TMF1/VPS8/PEF1/P2RX7/CHMP3/PPP6R1/RAB1B/TRIM9/DLG4/USO1	96
BP	GO:0051028	mRNA transport	48/4749	152/18670	0.05157	0.2257	0.1836	MVP/SEC13/U2AF1/ZFP36/NUP98/SMG5/POLDIP3/IWS1/RNPS1/HNRNPA3/ENY2/SRSF4/ZC3H3/NUP153/UPF1/MAGOHB/ALKBH5/SUPT6H/NUP88/THOC3/FMR1/U2AF1L4/PARP11/POM121C/NUP205/RAE1/NUP50/DHX38/UPF3A/MAGOH/LRPPRC/CPSF1/SMG6/ZFP36L1/GLE1/CETN2/NUP93/DDX19A/CDC40/CETN3/NUP35/AAAS/NCBP2/NUP62/SEH1L/KHSRP/YTHDC1/NXF3	48
BP	GO:0035601	protein deacylation	34/4749	103/18670	0.05164	0.2258	0.1837	VEGFA/RCOR1/BCL6/SPRED2/SFPQ/ZNHIT1/SIRT6/SKI/FOXP3/MORF4L2/PPT1/PER2/ELK4/PINK1/LYPLAL1/SIRT3/MIER2/C6orf89/SAP30L/BEX4/SIRT2/CAMK2D/KDM5A/BAZ2A/SPHK2/MTA1/CTBP1/HDAC9/MTA3/SIRT7/TGFB1/HDAC10/USP17L2/SIRT1	34
BP	GO:0009308	amine metabolic process	44/4749	138/18670	0.05218	0.2276	0.1852	SMOX/SMS/ABAT/MOXD1/PSMD8/ATCAY/PSMD1/PSMD2/HPRT1/SARDH/PSMF1/GDPD1/NQO1/SAT1/OAZ3/BHMT/DRD1/PSMD9/ATP2B4/PSMA5/PARK7/PSMB7/OAZ2/PSMD5/IDO1/TPH1/PSME2/SATL1/PSMB5/GDE1/AANAT/DHPS/PSMB4/PSMA3/ALDH7A1/OAZ1/PSMD10/PSMB1/PSMD7/PSMB3/HDAC10/PSMC5/PSMD11/SLC44A1	44
BP	GO:0030048	actin filament-based movement	44/4749	138/18670	0.05218	0.2276	0.1852	MYO7A/DSC2/MYO1E/MYH10/WIPF2/MYLK2/RNF207/MYO5A/SCN1B/PDE4D/MYL6/ATP2A1/KCNE3/PDE4B/SRI/KCNJ2/SUN2/MYL1/TRPM4/ACTN4/TPM2/MYBPC3/SUMO1/MYH7/EPB41L5/TNNC1/MYH4/MYO9B/VIM/MYL6B/CAMK2D/KCNH2/MYH9/KCNE4/KCND3/TPM1/CACNB2/WASF2/MYH6/TCAP/WAS/MYBPC2/SYNE2/GJA5	44
BP	GO:0006575	cellular modified amino acid metabolic process	62/4749	202/18670	0.05219	0.2276	0.1852	P4HA2/MTHFD2/MTHFD1L/CHAC1/SLC6A8/TYMS/SERINC3/GAMT/ABHD16A/ETHE1/CTNS/GPX1/CHAC2/CARNS1/VNN2/GGT1/CPQ/GGH/PLA2G12A/MTHFS/SARDH/DHFR/OPLAH/MRI1/TMLHE/LPCAT3/MTHFD1/BHMT/GGTLC2/GPX4/PARK7/MMACHC/CKB/MTRR/GSTM1/LPCAT4/GNMT/GSTT1/P4HTM/ENOPH1/CPT1A/PLA2G2A/POR/MGST2/GCLC/GGT7/AASDHPPT/ALDH7A1/ALDH9A1/VNN1/PLOD3/PTDSS1/GSTK1/PLA2G5/GSS/ALDH5A1/SLC22A4/MBOAT1/GSTZ1/PDZD11/GATA3/BHMT2	62
BP	GO:0031398	positive regulation of protein ubiquitination	38/4749	117/18670	0.05232	0.2276	0.1852	NDFIP2/UBE2C/CDC20/FANCI/GORASP1/UBE2S/HSPA5/DERL1/ARRDC3/PLK1/SMAD7/ARRB1/UBB/CRY1/UBE2N/RNF40/PINK1/ARRDC4/NOD2/FKBP1A/UBE3A/TOPORS/DCUN1D4/BIRC3/GSK3A/CDC14B/RIPK2/TRAF6/BIRC7/MTA1/RAB1A/PSMD10/PHF23/BMI1/PEF1/FBXO4/TRIB3/MAGEA2B	38
BP	GO:0001959	regulation of cytokine-mediated signaling pathway	55/4749	177/18670	0.05233	0.2276	0.1852	IRF7/PPARG/IL1R1/PTPN6/IL1RN/TREX1/CBFB/RFFL/TNF/CSF1/HSPA1A/NOL3/PTPN1/AGPAT2/MMP12/IL1R2/PARP14/SOCS3/TRAIP/CLIP3/AXL/CD74/IRAK3/PTPRC/SIGIRR/CD300LF/PIAS1/CYLD/ABCE1/SCRIB/TRIM44/TXK/IRAK1/ARG1/SUMO1/CREBRF/TRAF1/IRF3/SAMHD1/IL7/RABGEF1/BIRC3/CNOT7/YTHDF3/PADI2/TRAF2/IFNGR1/PIAS4/ADIPOQ/RIPK2/STAT1/CARD8/ZNF675/SPATA2/JAK1	55
BP	GO:0055076	transition metal ion homeostasis	42/4749	131/18670	0.05235	0.2276	0.1852	TTC7A/ATP6V0D1/TFRC/SCO2/SLC39A7/TMPRSS6/MT1E/MT2A/STEAP3/FXN/HMOX1/TMC8/ATP13A2/SRI/HEPH/NUBP1/MT1X/ATP6V1A/SLC25A28/AP3D1/MT1H/FTL/MT1G/ACO1/NCOA4/EPAS1/FTH1/SCO1/BDH2/ATP6V1G1/S100A8/PRNP/ISCU/MT1A/HMOX2/CYBRD1/MT1B/MT1M/SLC39A10/CCDC115/SLC40A1/MT1F	42
BP	GO:0098754	detoxification	42/4749	131/18670	0.05235	0.2276	0.1852	TXNDC17/ALOX5AP/TNF/MT1E/MT2A/GPX1/PRDX3/PRDX5/HBA2/NQO1/DHFR/MT1X/GSTO1/NXN/FANCC/MT1H/IPCEF1/TP53INP1/GPX4/MT1G/PARK7/TXNRD3/GSTM1/MPO/HBG1/PRDX6/GSTT1/HBB/MT1A/MGST2/NNT/MT1B/MT1M/MGST3/GSTK1/CCS/TXNRD2/GSTZ1/SESN2/AKR1A1/PRDX1/MT1F	42
BP	GO:0014013	regulation of gliogenesis	40/4749	124/18670	0.0524	0.2276	0.1852	LIF/IL1B/NOTCH1/TP73/CDK1/PPARG/DUSP10/TTBK1/NF2/TNF/CSF1/E2F1/SKI/TNFRSF21/MTOR/LDLR/TSPO/CCR2/ETV5/TIAM1/CCL3/NTRK3/SPINT1/PRKCI/EZH2/TLR2/SLC45A3/LRP1/LTA/SOX8/WDR1/SOX11/PRPF19/SIRT2/TNFRSF1B/DICER1/MBD1/NKX6-2/TGFB1/CX3CR1	40
BP	GO:0006361	transcription initiation from RNA polymerase I promoter	14/4749	36/18670	0.05245	0.2276	0.1852	UBTF/SMARCB1/CDK7/SMARCA4/ERCC2/GTF2H2/GTF2H1/TAF1A/ZNRD1/MNAT1/TAF1D/BAZ2A/GTF2H5/POLR1B	14
BP	GO:0006882	cellular zinc ion homeostasis	14/4749	36/18670	0.05245	0.2276	0.1852	SLC39A7/MT1E/MT2A/ATP13A2/MT1X/AP3D1/MT1H/MT1G/S100A8/MT1A/MT1B/MT1M/SLC39A10/MT1F	14
BP	GO:2000516	positive regulation of CD4-positive, alpha-beta T cell activation	14/4749	36/18670	0.05245	0.2276	0.1852	CD86/IL18/NLRP3/CD83/CD80/TNFSF4/LGALS9/FOXP3/IL4R/HLX/IL12RB1/RIPK2/RARA/IL23A	14
BP	GO:0006400	tRNA modification	29/4749	86/18670	0.05311	0.2302	0.1873	QTRT1/TRMT12/CTU1/GTPBP3/ALKBH8/TRMT1/OSGEPL1/ELP5/TARBP1/PUS1/NSUN6/TRMT10B/SEPHS1/TRMT13/TRIT1/ELP4/TRMT112/PUSL1/METTL8/DUS1L/KTI12/MTFMT/TRMT10C/C9orf64/TRMT1L/THG1L/NSUN2/CDKAL1/PUS10	29
BP	GO:0032760	positive regulation of tumor necrosis factor production	29/4749	86/18670	0.05311	0.2302	0.1873	TWIST1/TIRAP/CLEC7A/LGALS9/HMGB1/TNFRSF8/CYBB/TLR4/LILRA2/CARD9/CCR2/ARHGEF2/CCL3/CLU/HAVCR2/PTPRC/HLA-E/TLR2/NOD2/CYBA/LILRA5/IFNGR1/RIPK2/MAPKAPK2/TYROBP/FZD5/DDT/PTAFR/IL23A	29
BP	GO:0009451	RNA modification	51/4749	163/18670	0.05353	0.2316	0.1884	APOBEC3H/APOBEC3B/QTRT1/TRMT12/NUDT16/CTU1/GTPBP3/ALKBH8/NSUN4/TRMT1/NOP10/NSUN5P1/ALKBH5/OSGEPL1/ELP5/TARBP1/AICDA/PUS1/NSUN6/RBM47/TRMT10B/TRUB2/SEPHS1/TRMT13/TRIT1/ELP4/TRMT112/RPUSD1/PUSL1/METTL8/EMG1/PUS7L/DUS1L/TRMT2A/KTI12/FBL/FDXACB1/RRNAD1/METTL16/MTFMT/ZCCHC4/TRMT10C/C9orf64/TRMT1L/THG1L/TFB2M/NSUN2/A1CF/ALKBH3/CDKAL1/PUS10	51
BP	GO:0001885	endothelial cell development	21/4749	59/18670	0.05358	0.2316	0.1884	IL1B/VEGFA/ICAM1/TNF/PROC/COL18A1/TJP2/MYADM/GPX1/PDE4D/EZR/WNT7A/PPP1R16B/RAPGEF1/RAPGEF2/PTPRS/FASN/PLOD3/ID1/CDH5/ARHGEF26	21
BP	GO:0032732	positive regulation of interleukin-1 production	21/4749	59/18670	0.05358	0.2316	0.1884	EGR1/NLRP3/TLR8/HK1/CLEC7A/LGALS9/HMGB1/TLR4/LILRA2/CCL3/HAVCR2/NOD2/MNDA/LILRA5/IFI16/RIPK2/TYROBP/CARD8/FZD5/TRIM16/P2RX7	21
BP	GO:2000756	regulation of peptidyl-lysine acetylation	21/4749	59/18670	0.05358	0.2316	0.1884	TWIST1/LIF/IL1B/SPI1/FOXP3/SMARCB1/NAP1L2/IWS1/ARRB1/KAT2A/MUC1/CHEK1/TAF7/TADA2A/SPHK2/CTBP1/TGFB1/ZNF451/GATA3/HINT2/SIRT1	21
BP	GO:0007259	JAK-STAT cascade	49/4749	156/18670	0.05406	0.2334	0.1899	LIF/NOTCH1/IL18/CSF2/IL21/CSF1R/IL10/DOT1L/BCL3/TNFRSF18/CNTF/NF2/PPP2R1A/SOCS2/STAMBP/TNF/PTPN1/STAT3/PARP14/CCR2/SOCS3/PKD2/FLT3/CCL2/PTK6/PTPRC/PIAS1/PPP2CA/ADIPOR1/IL26/OSM/HGS/STAT4/GGNBP2/PIBF1/CNOT7/IL13/IL20/IL4/ARL2BP/F2R/CRLF3/FER/STAT5A/STAT1/IL10RA/JAK3/FYN/IL23A	49
BP	GO:1901655	cellular response to ketone	31/4749	93/18670	0.05408	0.2334	0.1899	PPARG/ICAM1/CASP9/KLF2/KLF4/TNFSF4/SPP1/EIF4EBP1/NR3C1/SRC/CFLAR/NDOR1/PTGER4/ADCY6/DCPS/FOXO1/DDIT4/KLF9/ARG1/PARK7/ELK1/PRKCE/PTGER2/ADCY3/ADAM15/SFRP1/CDC5L/MAP4K1/SPHK2/TGFB1/SIRT1	31
BP	GO:0006471	protein ADP-ribosylation	13/4749	33/18670	0.0547	0.2355	0.1916	SIRT6/PARP14/PARP2/TNKS2/PARP16/PARP11/XRCC1/ARF4/SIRT2/PARP6/PARP8/TINF2/ADNP	13
BP	GO:0009303	rRNA transcription	13/4749	33/18670	0.0547	0.2355	0.1916	GTF3C4/MTOR/SMARCB1/GTF3C2/SMARCA4/NCL/NPM3/DDX11/GTF3C6/IPPK/SIRT7/POLR1B/SPIN1	13
BP	GO:0010039	response to iron ion	13/4749	33/18670	0.0547	0.2355	0.1916	CPOX/MAP1LC3A/FXN/CCNB1/HMOX1/ABAT/ACO1/TFF1/C1QA/CYBRD1/CCND1/SLC40A1/PDX1	13
BP	GO:0040001	establishment of mitotic spindle localization	13/4749	33/18670	0.0547	0.2355	0.1916	ESPL1/SAPCD2/CENPA/GPSM2/NUSAP1/PLK1/NUMA1/NDC80/ARHGEF2/HTT/ACTR1A/NSFL1C/MCPH1	13
BP	GO:0036503	ERAD pathway	33/4749	100/18670	0.05476	0.2356	0.1916	HSPA5/SDF2L1/DERL1/UBXN6/TRIM25/SYVN1/POMT2/VCP/DNAJB12/USP19/HERPUD1/UBXN1/NPLOC4/FBXO27/UBE4A/SGTA/UBE2G2/BCAP31/TRIM13/SEC61B/RCN3/JKAMP/SDF2/EDEM2/BRSK2/UBQLN2/RNF139/TMEM67/RNF121/TMUB2/FBXO44/DNAJB2/UBAC2	33
BP	GO:0036293	response to decreased oxygen levels	108/4749	370/18670	0.05481	0.2356	0.1916	EGR1/TWIST1/VEGFA/NOTCH1/ITGA2/ICAM1/SRF/BNIP3L/CCNA2/LDHA/PTGIS/ENO1/PML/EIF4EBP1/CBFA2T3/SLC2A8/E2F1/HK2/CYBB/NOL3/PLEKHN1/PLAU/PMAIP1/MTOR/LMNA/PLAT/CCNB1/SRC/HMOX1/PKM/ABAT/LIMD1/PSMD8/CFLAR/PAM/USP19/UBB/PSMD1/TGFB3/PSMD2/PAK1/RBPJ/ATF4/SLC2A4/PSMF1/RPS27A/ATP1B1/CASR/KCNMB1/PICK1/PINK1/NAMPT/NDRG1/ALKBH5/DDIT4/ACTN4/UBA52/TLR2/PSMD9/IRAK1/PSMA5/VASN/MDM4/LTA/PSMB7/ERCC2/HIF3A/PRKCE/AK4/EPAS1/PSMD5/CITED2/CYBA/ADAM15/PSME2/XRCC1/SFRP1/ADM/SIRT2/ALDH3A1/ADIPOQ/PSMB5/CD34/HMOX2/ZFP36L1/CPEB1/PSMB4/MALAT1/PSMA3/HIF1AN/BACH1/ATM/PPARD/ARNT2/CLCA1/PSMD10/TGFB1/PSMB1/PSMD7/PSMB3/KCNK2/PSMC5/VEGFC/BAD/MGARP/FUNDC1/PSMD11/SIRT1	108
BP	GO:0006469	negative regulation of protein kinase activity	71/4749	235/18670	0.05489	0.2356	0.1916	IL1B/CDKN1A/WNK1/MVP/DUSP10/CAMK2N2/ADORA2A/DUSP4/TRIB1/CDKN2B/GSKIP/PTPN6/DUSP6/SPRED2/HEXIM1/DNAJA1/CEACAM1/CORO1C/NF2/PPP2R1A/PTPN1/PLK1/CDKN2C/GADD45A/PDCD4/SORL1/SOCS3/FGFR1OP/DUSP5/SFN/IGF1R/WWTR1/IRAK3/PTK6/DUSP16/PTPRC/SH3BP5L/DUSP22/DVL1/PPP2CA/CHORDC1/CDKN2A/GBA/DTNBP1/THY1/TAOK3/PRKAG2/CHP1/PARK7/GGNBP2/DEFB114/DEPTOR/DUSP18/SFRP1/ADIPOQ/TAF7/TESC/AIDA/LRP6/STK38/GNAQ/DUSP14/APC/ZNF675/UCHL1/NUP62/PAK2/TRIB3/ILK/SIRT1/DUSP1	71
BP	GO:0001666	response to hypoxia	105/4749	359/18670	0.0549	0.2356	0.1916	EGR1/TWIST1/VEGFA/NOTCH1/ITGA2/ICAM1/SRF/BNIP3L/CCNA2/LDHA/PTGIS/ENO1/PML/EIF4EBP1/CBFA2T3/SLC2A8/E2F1/HK2/CYBB/NOL3/PLEKHN1/PLAU/PMAIP1/MTOR/LMNA/PLAT/CCNB1/SRC/HMOX1/PKM/ABAT/LIMD1/PSMD8/CFLAR/PAM/USP19/UBB/PSMD1/TGFB3/PSMD2/PAK1/RBPJ/SLC2A4/PSMF1/RPS27A/ATP1B1/CASR/KCNMB1/PINK1/NDRG1/ALKBH5/DDIT4/ACTN4/UBA52/TLR2/PSMD9/IRAK1/PSMA5/VASN/MDM4/LTA/PSMB7/ERCC2/HIF3A/PRKCE/AK4/EPAS1/PSMD5/CITED2/CYBA/ADAM15/PSME2/XRCC1/SFRP1/ADM/SIRT2/ALDH3A1/ADIPOQ/PSMB5/CD34/HMOX2/ZFP36L1/CPEB1/PSMB4/MALAT1/PSMA3/HIF1AN/BACH1/ATM/PPARD/ARNT2/CLCA1/PSMD10/TGFB1/PSMB1/PSMD7/PSMB3/KCNK2/PSMC5/VEGFC/BAD/MGARP/FUNDC1/PSMD11/SIRT1	105
BP	GO:0045454	cell redox homeostasis	26/4749	76/18670	0.05494	0.2356	0.1916	SCO2/NCF4/CYBB/GPX1/PRDX3/TXNDC5/PDIA4/PRDX5/QSOX1/NXN/HVCN1/DDIT3/TXNRD3/RAC2/PTGES2/TXNDC12/MPO/CYBA/PRDX6/KRIT1/GCLC/NNT/NCF1/NME9/TXNRD2/PRDX1	26
BP	GO:0061045	negative regulation of wound healing	26/4749	76/18670	0.05494	0.2356	0.1916	CD109/CDKN1A/DUSP10/PDGFA/PLAUR/ANXA2P2/CEACAM1/CD9/PROS1/TMPRSS6/PROC/PLAU/SERPINE1/ADTRP/ANXA2/PLAT/ABAT/CLASP2/ANXA5/VTN/CRK/KLKB1/SERPING1/CD34/PDGFB/TFPI	26
BP	GO:0017157	regulation of exocytosis	66/4749	217/18670	0.05509	0.2359	0.1919	NOTCH1/SDC4/ADORA2A/MICAL1/FES/RIMS3/CDK5/CEACAM1/LGALS9/SYN1/NCS1/CHRNA5/GAB2/HYAL3/IL4R/SNF8/CCR2/HMOX1/P2RX1/SYT4/HTR2A/SDCBP/ATP13A2/CAMK2A/STAM/CD177/RAB3D/PFN2/RSC1A1/APBA2/STXBP5/STX1B/SDC1/CLASP2/DVL1/DRD1/RALA/DTNBP1/HGS/GNAI2/RAB27A/WNT7A/CNR1/UNC13D/FMR1/SYT11/RAC2/RABGEF1/IL13/SNAPIN/NAPB/LAMP1/FER/DOC2B/PRKCB/P2RY1/CHMP2A/RAB15/SPHK2/CACNB2/BCR/FBXL20/RALB/SYT15/PTAFR/TRIM9	66
BP	GO:0071241	cellular response to inorganic substance	66/4749	217/18670	0.05509	0.2359	0.1919	RASGRP2/PPIF/WNK1/CPNE7/CCNA2/TREX1/ALOX5AP/MMP9/FOSB/HSPA5/GSN/CYBB/MAP1LC3A/MT1E/SLC25A23/MT2A/TSPO/CCNB1/HMOX1/SYT4/CFLAR/ATP13A2/CDK2/CPNE5/PKD2/ATF4/NQO1/FOXO1/AQP2/MT1X/ANXA5/TIMELESS/MT1H/HVCN1/SUMO1/MT1G/JUN/PPP5C/FMR1/RASA4/ACER1/CRK/SYT11/ECT2/RASAL1/CLIC4/BRAF/DDX11/TRAF2/EIF2AK3/CAMK2D/PRNP/MT1A/MTR/MT1B/MT1M/NCF1/CPNE4/FOS/OGG1/SYT15/MAPK1/SLC40A1/MT1F/BAD/DLG4	66
BP	GO:0030010	establishment of cell polarity	43/4749	135/18670	0.05522	0.2363	0.1923	SAPCD2/CENPA/GPSM2/FSCN1/KIF20B/FRMD4B/EPHB1/GSN/PLK1/DOCK8/FRMD4A/NUMA1/NDC80/ARHGEF2/PAK1/PTK7/AMOT/HTT/MPP7/FAM89B/FGF13/MPP5/WDPCP/PRKCI/CFL1/SCRIB/WNT7A/GBF1/CRK/BRSK2/KRIT1/MYH9/ACTR1A/NSFL1C/CYTH1/ARF6/MCPH1/RUFY3/BCAS3/CDC42/KIF26B/CDH5/GATA3	43
BP	GO:0002687	positive regulation of leukocyte migration	41/4749	128/18670	0.05543	0.237	0.1928	CXCL13/VEGFA/ITGA2/WNK1/ICAM1/IL1R1/CCL20/RAC1/TNFRSF18/TIRAP/CCR1/DAPK2/LGALS3/LGALS9/HMGB1/TNF/CSF1/CXCL10/SERPINE1/DOCK8/SWAP70/CCR6/CCR2/CCL3/CD74/AIF1/THY1/FPR2/C3AR1/RAC2/CD99L2/RARRES2/ITGA2B/C1QBP/CCL7/THBS4/TGFB1/PTAFR/CCL27/VEGFC/IL23A	41
BP	GO:0030968	endoplasmic reticulum unfolded protein response	39/4749	121/18670	0.05551	0.2372	0.193	ATP6V0D1/ATF3/HSPA5/CREB3L2/SERP2/DERL1/BAX/TPP1/PTPN1/ZBTB17/LMNA/SYVN1/VCP/HERPUD1/ATF4/ASNS/CTH/CCL2/EXTL2/PARP16/BAK1/DDIT3/CREBRF/FICD/GSK3A/KLHDC3/YIF1A/DDX11/EIF2AK3/ERN1/SERP1/CANX/RNF121/MBTPS2/PPP1R15A/HERPUD2/TMEM33/CCND1/SHC1	39
BP	GO:0002715	regulation of natural killer cell mediated immunity	17/4749	46/18670	0.05579	0.2375	0.1932	IL21/CEACAM1/LGALS9/ULBP2/RAET1E/HLA-G/SH2D1A/HAVCR2/HLA-E/MICA/LAG3/CADM1/CRK/LAMP1/ULBP1/KLRK1/CD96	17
BP	GO:0032527	protein exit from endoplasmic reticulum	17/4749	46/18670	0.05579	0.2375	0.1932	SEC13/DERL1/RANGRF/SYVN1/SORL1/SEC16A/VCP/HERPUD1/NPLOC4/UBE2G2/BCAP31/INSIG1/SEC61B/TMEM30A/EDEM2/BRSK2/UBAC2	17
BP	GO:0043300	regulation of leukocyte degranulation	17/4749	46/18670	0.05579	0.2375	0.1932	FES/CEACAM1/LGALS9/GAB2/IL4R/CCR2/HMOX1/CD177/UNC13D/RAC2/RABGEF1/IL13/LAMP1/FER/SPHK2/BCR/PTAFR	17
BP	GO:0050706	regulation of interleukin-1 beta secretion	17/4749	46/18670	0.05579	0.2375	0.1932	NLRP3/TLR8/HK1/LGALS9/PML/HMGB1/TLR4/LILRA2/CCL3/NOD2/ZC3H12A/LILRA5/RIPK2/CARD8/FZD5/TRIM16/P2RX7	17
BP	GO:0060711	labyrinthine layer development	17/4749	46/18670	0.05579	0.2375	0.1932	IL10/PLCD3/ST14/VASH1/SOCS3/RBPJ/SPINT1/PCDH12/GGNBP2/HS6ST1/DNAJB6/ADM/RSPO3/ZFP36L1/FZD5/MAPK1/GCM1	17
BP	GO:1900015	regulation of cytokine production involved in inflammatory response	17/4749	46/18670	0.05579	0.2375	0.1932	IL17A/SIRPA/CLEC7A/TLR4/ABCD1/IL1R2/PDCD4/ABCD2/BAP1/C5orf30/NOD2/TLR6/IL17RC/NLRC3/ZC3H12A/CHID1/CD6	17
BP	GO:0007565	female pregnancy	59/4749	192/18670	0.05585	0.2376	0.1933	VDR/LIF/IL1B/ITGA2/FOSL1/ITGA3/UBE2A/PTGIS/SPP1/MMP9/LGALS9/PRDM1/FOSB/DHODH/ADRA2B/TEAD3/MTOR/PRDX3/PAM/HAVCR2/TGFB3/PTHLH/CTSB/OVGP1/BYSL/NAMPT/UPRT/ADIPOR2/ARG1/RXRA/CNR1/ARID1A/SLC38A2/CYP27B1/ACVR1C/TIMP1/RECK/RPL29/IDO1/DDR1/BSG/ACSL4/ADM/GHRL/ESR1/LNPEP/C1QBP/SPHK2/PCSK5/HPGD/FOS/PSG11/NPFF/PPARD/TGFB1/RARA/MAPK1/CLDN4/POLR1B	59
BP	GO:0006513	protein monoubiquitination	23/4749	66/18670	0.05626	0.2392	0.1946	DTL/UHRF1/DDB2/UBE2B/TRIM25/RYBP/DTX3L/UBE3D/UBB/BCOR/RNF40/ZNF598/PCGF6/MGRN1/PCGF1/TOPORS/PCGF5/KLHL22/WDR48/BMI1/PEF1/RNF168/UBE2W	23
BP	GO:0051402	neuron apoptotic process	72/4749	239/18670	0.05662	0.2405	0.1957	KIF14/TYRO3/NR4A3/CASP9/ADORA2A/NTRK2/CIT/FAIM2/NTRK1/GAPDH/GRN/CNTF/VSTM2L/MYBL2/MCL1/CDK5/TP63/STAMBP/ASCL1/HSPA5/TNF/FOXB1/USP53/BAX/TNFRSF21/HMOX1/ARRB1/CCL3/AXL/TGFB3/PPT1/ATF4/AMBRA1/CCL2/NQO1/PAK3/BID/PINK1/CORO1A/ITGA1/PRKCI/MAP3K11/LRP1/DDIT3/PARK7/JUN/TFAP2B/AGAP2/CTSZ/CEBPB/BCL2L1/MAP2K4/PRNP/F2R/NAE1/TYROBP/FZD9/GCLC/MAX/NUPR1/FGF8/NEFL/NTF3/ATM/POU4F1/NMNAT1/ADNP/GATA3/CX3CR1/FYN/ILK/PIGT	72
BP	GO:0006749	glutathione metabolic process	20/4749	56/18670	0.05674	0.2406	0.1958	CHAC1/ETHE1/CTNS/GPX1/CHAC2/GGT1/OPLAH/GGTLC2/GPX4/PARK7/MMACHC/GSTM1/GSTT1/MGST2/GCLC/GGT7/GSTK1/GSS/ALDH5A1/GSTZ1	20
BP	GO:1903078	positive regulation of protein localization to plasma membrane	20/4749	56/18670	0.05674	0.2406	0.1958	SQSTM1/ITGA3/LGALS3/TNF/AKAP5/RANGRF/RHOG/CLIP3/PLS1/PTPN9/SPTBN1/EZR/PRKCI/STAC3/LRP1/STAC/PRKCE/PRNP/ARF6/CNST	20
BP	GO:0006362	transcription elongation from RNA polymerase I promoter	12/4749	30/18670	0.05687	0.2406	0.1958	UBTF/CDK7/ERCC2/GTF2H2/GTF2H1/TAF1A/ZNRD1/MNAT1/TAF1D/GTF2H5/POU4F1/POLR1B	12
BP	GO:0035066	positive regulation of histone acetylation	12/4749	30/18670	0.05687	0.2406	0.1958	LIF/IL1B/FOXP3/SMARCB1/NAP1L2/ARRB1/KAT2A/MUC1/TADA2A/SPHK2/TGFB1/GATA3	12
BP	GO:0046320	regulation of fatty acid oxidation	12/4749	30/18670	0.05687	0.2406	0.1958	TWIST1/NR4A3/PPARG/MTOR/ABCD1/ABCD2/TYSND1/PRKAG2/CNR1/CPT1A/DGAT2/ACACB	12
BP	GO:0048873	homeostasis of number of cells within a tissue	12/4749	30/18670	0.05687	0.2406	0.1958	NOTCH1/CSF1/AKT3/BAX/CCR2/CORO1A/IL7/GIGYF2/F2R/LIPA/P2RX7/RAC3	12
BP	GO:0046879	hormone secretion	92/4749	312/18670	0.05742	0.2428	0.1975	LIF/IL1B/ADORA2A/RAC1/IL1RN/PIM3/RAB11FIP1/SLC16A1/NMB/SPP1/TNF/ADRA2B/SCG5/BLK/FFAR2/MYO5A/TIAM1/ABAT/ARRB1/BTK/GNAS/ENY2/C2CD2L/SRI/CRY1/ENHO/PER2/CCKAR/FFAR3/CASR/TCF7L2/KDM5B/PRKCA/TRPM4/NADK/ANXA5/OXCT1/PFKFB2/PSMD9/LRP1/SNAP23/OSM/CACNA2D2/SIRT3/ILDR1/CNR1/C1QTNF3/PARK7/TFAP2B/RAB11FIP3/ACVR1C/SLC25A5/ACVR2B/SNX19/CAMK2G/PRKCE/TACR2/SIDT2/LRP5L/SOX11/ARNTL/GLUD1/BRSK2/SFRP1/ADM/GHRL/KCNG2/ADIPOQ/CPT1A/ARL2BP/RAB11FIP5/SERP1/DOC2B/CHRNA3/FAM3B/P2RY1/RAB1A/SLC25A4/PFKL/TNFSF11/ARL2/NPFF/PPARD/SLC9B2/FFAR1/TMF1/NDUFAF2/GATA3/PDX1/GIPR/SYBU/BAD	92
BP	GO:0051384	response to glucocorticoid	46/4749	146/18670	0.05766	0.2436	0.1982	CDKN1A/ICAM1/CASP9/FOSL1/IL10/IL1RN/GLB1/FOSB/TYMS/EIF4EBP1/TNF/ZFP36/NR3C1/PPARGC1B/CFLAR/PAM/NTRK3/FLT3/FOXO1/ZFP36L2/SDC1/DDIT4/AIF1/KLF9/GBA/ARG1/CREBRF/IL22/BGLAP/ADM/HSD3B2/ALDH3A1/ADIPOQ/AANAT/ZFP36L1/AKAP13/NEFL/ABCA3/FOS/TGFB1/CCND1/ADAM9/PTAFR/PDX1/BAD/DUSP1	46
BP	GO:0002685	regulation of leukocyte migration	60/4749	196/18670	0.05795	0.2436	0.1982	CXCL13/VEGFA/ITGA2/WNK1/ICAM1/IL1R1/CCL20/RAC1/TNFRSF18/TIRAP/CCR1/DAPK2/LGALS3/LGALS9/CD9/HMGB1/TNF/CSF1/CD200/CXCL10/SERPINE1/ADTRP/DOCK8/SWAP70/CCR6/RIPK3/CCR2/HMOX1/GCSAM/CCL3/PTGER4/CD74/CCL2/AIF1/IL27RA/THY1/FPR2/C3AR1/CRK/RAC2/CD99L2/RABGEF1/PADI2/RARRES2/ITGA2B/C1QBP/BCR/GCSAML/CCL7/THBS4/DDT/PLCB1/TGFB1/KLRK1/PTAFR/CCL27/CX3CR1/VEGFC/IL23A/DUSP1	60
BP	GO:0048709	oligodendrocyte differentiation	32/4749	97/18670	0.05809	0.2436	0.1982	NOTCH1/TP73/PPARG/DUSP10/NTRK2/CDK5/CD9/ASCL1/GSN/CDKN2C/TNFRSF21/MTOR/CNP/PRDM8/NKX2-1/FA2H/CLU/EIF2B3/TLR2/VTN/SLC45A3/SOX8/ERCC2/ERBB2/WDR1/SOX11/B4GALT5/TNFRSF1B/MED12/NKX6-2/TGFB1/HDAC10	32
BP	GO:0090630	activation of GTPase activity	32/4749	97/18670	0.05809	0.2436	0.1982	CXCL13/NEDD9/ADPRH/SIPA1L1/CORO1C/SGSM3/TBC1D9/TBC1D2B/RHOG/TIAM1/NTRK3/TBC1D22A/TBC1D10C/RUNDC1/TBC1D3H/TBC1D10B/CCDC125/SCRIB/TBC1D8/RAPGEF1/TBC1D22B/CRK/ECT2/TBC1D2/TBC1D13/TBCK/TBC1D3C/BCR/NTF3/PIP5K1A/BCAS3/RALGAPA1	32
BP	GO:1901983	regulation of protein acetylation	25/4749	73/18670	0.0583	0.2436	0.1982	TWIST1/LIF/IL1B/SPI1/CAMK1/FOXP3/SMARCB1/NAP1L2/IWS1/ARRB1/KAT2A/MUC1/PARK7/CHEK1/ARNTL/TAF7/TADA2A/SPHK2/CTBP1/TGFB1/ZNF451/GATA3/HINT2/MAGEA2B/SIRT1	25
BP	GO:0098732	macromolecule deacylation	34/4749	104/18670	0.05854	0.2436	0.1982	VEGFA/RCOR1/BCL6/SPRED2/SFPQ/ZNHIT1/SIRT6/SKI/FOXP3/MORF4L2/PPT1/PER2/ELK4/PINK1/LYPLAL1/SIRT3/MIER2/C6orf89/SAP30L/BEX4/SIRT2/CAMK2D/KDM5A/BAZ2A/SPHK2/MTA1/CTBP1/HDAC9/MTA3/SIRT7/TGFB1/HDAC10/USP17L2/SIRT1	34
BP	GO:0002863	positive regulation of inflammatory response to antigenic stimulus	6/4749	12/18670	0.05866	0.2436	0.1982	TNF/BTK/HLA-E/LTA/CNR1/PARK7	6
BP	GO:0006264	mitochondrial DNA replication	6/4749	12/18670	0.05866	0.2436	0.1982	RRM2B/DNAJA3/DNA2/POLG2/SSBP1/ATG7	6
BP	GO:0009265	2'-deoxyribonucleotide biosynthetic process	6/4749	12/18670	0.05866	0.2436	0.1982	TYMS/CMPK2/DTYMK/AK5/DCTD/GUK1	6
BP	GO:0010826	negative regulation of centrosome duplication	6/4749	12/18670	0.05866	0.2436	0.1982	CCNF/KAT2A/NUBP1/MDM1/TMEM67/CHMP2A	6
BP	GO:0035330	regulation of hippo signaling	6/4749	12/18670	0.05866	0.2436	0.1982	NF2/LIMD1/WWC2/SOX11/NEK8/DLG5	6
BP	GO:0046385	deoxyribose phosphate biosynthetic process	6/4749	12/18670	0.05866	0.2436	0.1982	TYMS/CMPK2/DTYMK/AK5/DCTD/GUK1	6
BP	GO:0046520	sphingoid biosynthetic process	6/4749	12/18670	0.05866	0.2436	0.1982	GBA/ACER1/ACER2/ASAH2/ASAH2B/SPHK2	6
BP	GO:0071481	cellular response to X-ray	6/4749	12/18670	0.05866	0.2436	0.1982	TP53BP1/XRCC6/SFRP1/ATM/NUCKS1/GATA3	6
BP	GO:0071888	macrophage apoptotic process	6/4749	12/18670	0.05866	0.2436	0.1982	IRF7/CCR5/CDKN2A/NOD2/IRF3/SIRT1	6
BP	GO:0072017	distal tubule development	6/4749	12/18670	0.05866	0.2436	0.1982	NOTCH1/KLHL3/PKD2/JAG1/TFAP2B/UMOD	6
BP	GO:0072540	T-helper 17 cell lineage commitment	6/4749	12/18670	0.05866	0.2436	0.1982	BATF/IRF4/STAT3/LY9/IL12RB1/IL23A	6
BP	GO:0090085	regulation of protein deubiquitination	6/4749	12/18670	0.05866	0.2436	0.1982	VCP/UBXN1/TANK/PARK7/ZC3H12A/WDR48	6
BP	GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress	6/4749	12/18670	0.05866	0.2436	0.1982	HSPA1A/JUN/CITED2/BAG3/SIRT2/HIF1AN	6
BP	GO:0097284	hepatocyte apoptotic process	6/4749	12/18670	0.05866	0.2436	0.1982	GSN/CFLAR/BID/STK3/BCL2L1/ARF6	6
BP	GO:0150065	regulation of deacetylase activity	6/4749	12/18670	0.05866	0.2436	0.1982	VEGFA/PINK1/C6orf89/CAMK2D/KDM5A/SPHK2	6
BP	GO:1900165	negative regulation of interleukin-6 secretion	6/4749	12/18670	0.05866	0.2436	0.1982	CD200/IL27RA/C1QTNF3/SYT11/ZC3H12A/RABGEF1	6
BP	GO:1903894	regulation of IRE1-mediated unfolded protein response	6/4749	12/18670	0.05866	0.2436	0.1982	HSPA5/BAX/PTPN1/BAK1/FICD/TMEM33	6
BP	GO:1905244	regulation of modification of synaptic structure	6/4749	12/18670	0.05866	0.2436	0.1982	CYFIP1/CHMP2B/CAMKV/GRIPAP1/TIAM1/FMR1	6
BP	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	102/4749	349/18670	0.05871	0.2436	0.1982	EGR1/SKIL/FURIN/CD109/NOTCH1/TTK/ITGA3/CDKN2B/LRG1/PMEPA1/ZYX/SNX25/TGFB1I1/PML/HSPA5/ARHGEF18/HSPA1A/SKI/TMPRSS6/USP9X/RGMA/MSX1/DAND5/SMAD7/PDCD4/SORL1/SRC/NKX2-1/NUMA1/SDCBP/GREM2/PELO/UBB/SFRP4/TGFB3/WWTR1/FGF9/ZFYVE9/RBPJ/ZC3H3/PRDM16/SMAD6/RUNX2/RPS27A/SMURF1/FAM89B/SPTBN1/ATOH8/UBA52/DUSP22/LEMD3/BTBD11/FKBP1A/IRAK1/FAM83G/VASN/GDF7/LDLRAD4/JUN/TFAP2B/FKBP8/ACVR1C/ACVR2B/TAB1/RBPMS2/EID2/CITED2/SOX11/VIM/ZNF703/SLC33A1/HTRA4/DACT2/SMAD1/SFRP1/LEFTY1/DLX5/LNPEP/BMP10/FGF8/BMP3/FBXL15/NUP93/RBPMS/HPGD/PARD6A/FOS/CER1/HTRA1/MYH6/ID1/RGMB/TGFB1/ZNF451/ADAM9/CDH5/VEPH1/PPM1L/MIR17HG/LRRC32/ILK/SIRT1	102
BP	GO:0006406	mRNA export from nucleus	36/4749	111/18670	0.05877	0.2436	0.1982	SEC13/U2AF1/NUP98/SMG5/POLDIP3/IWS1/RNPS1/ENY2/SRSF4/NUP153/UPF1/MAGOHB/ALKBH5/SUPT6H/NUP88/THOC3/U2AF1L4/POM121C/NUP205/RAE1/NUP50/DHX38/MAGOH/CPSF1/SMG6/GLE1/NUP93/DDX19A/CDC40/NUP35/AAAS/NCBP2/NUP62/SEH1L/YTHDC1/NXF3	36
BP	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus	36/4749	111/18670	0.05877	0.2436	0.1982	SEC13/U2AF1/NUP98/SMG5/POLDIP3/IWS1/RNPS1/ENY2/SRSF4/NUP153/UPF1/MAGOHB/ALKBH5/SUPT6H/NUP88/THOC3/U2AF1L4/POM121C/NUP205/RAE1/NUP50/DHX38/MAGOH/CPSF1/SMG6/GLE1/NUP93/DDX19A/CDC40/NUP35/AAAS/NCBP2/NUP62/SEH1L/YTHDC1/NXF3	36
BP	GO:0000096	sulfur amino acid metabolic process	16/4749	43/18670	0.05883	0.2436	0.1982	MPST/TST/GGT1/SMS/CTH/MRI1/MTHFD1/BHMT/MTRR/MTAP/GNMT/ENOPH1/GCLC/MTR/NFS1/BHMT2	16
BP	GO:0045429	positive regulation of nitric oxide biosynthetic process	16/4749	43/18670	0.05883	0.2436	0.1982	IL1B/ICAM1/KLF2/KLF4/CLEC7A/TNF/TLR4/DDAH2/MTOR/CLU/PKD2/AIF1/TLR6/HBB/INSR/KLRK1	16
BP	GO:0000188	inactivation of MAPK activity	11/4749	27/18670	0.05887	0.2436	0.1982	DUSP10/DUSP4/DUSP6/SPRED2/PPP2R1A/DUSP5/DUSP16/PPP2CA/DUSP18/DUSP14/DUSP1	11
BP	GO:0000460	maturation of 5.8S rRNA	11/4749	27/18670	0.05887	0.2436	0.1982	NOL9/ERI3/NOP14/EXOSC2/UTP20/BOP1/WDR12/ABT1/URB1/RCL1/EXOSC9	11
BP	GO:0039528	cytoplasmic pattern recognition receptor signaling pathway in response to virus	11/4749	27/18670	0.05887	0.2436	0.1982	IRF7/SEC14L1/NPLOC4/IRF3/BIRC3/C1QBP/TSPAN6/ANKRD17/ZCCHC3/USP17L2/TRIM15	11
BP	GO:0048143	astrocyte activation	11/4749	27/18670	0.05887	0.2436	0.1982	IL1B/ADORA2A/TTBK1/GRN/CNTF/TNF/LDLR/LRP1/FPR2/IFNGR1/C1QA	11
BP	GO:2000401	regulation of lymphocyte migration	22/4749	63/18670	0.05968	0.246	0.2001	CXCL13/WNK1/CCL20/CD200/CXCL10/ADTRP/DOCK8/CCR6/RIPK3/CCR2/GCSAM/CCL3/CCL2/AIF1/IL27RA/CRK/CD99L2/PADI2/GCSAML/CCL7/KLRK1/CCL27	22
BP	GO:0061138	morphogenesis of a branching epithelium	56/4749	182/18670	0.05979	0.246	0.2001	VDR/VEGFA/NOTCH1/IL10/SRF/PDGFA/CTSH/TP63/PTCH1/PML/ST14/TNF/CSF1/SIRT6/DCHS1/SRC/SOCS3/ETV5/NKX2-1/TGM2/PLXNA1/PAK1/PKD2/SPINT1/HOXB7/CASR/KDM5B/PLXND1/GREB1L/TIMELESS/FEM1B/RXRA/SOX8/GDF7/CTSZ/LRP5L/YAP1/NRARP/DDR1/BTRC/DLG5/SFRP1/ADM/RSPO3/ESR1/LRP6/HOXA11/FGF8/PBX1/FZD5/TGFB1/RDH10/LAMA5/ESRP2/ILK/GCM1	56
BP	GO:0097237	cellular response to toxic substance	74/4749	247/18670	0.06007	0.246	0.2001	EGR1/PPIF/CDK1/NR4A3/KLF2/IL10/TXNDC17/NTRK1/KLF4/SPI1/SIRPA/ALOX5AP/TNF/CYBB/MAP1LC3A/GPX1/PLEKHA1/MSX1/RIPK3/FXN/SRC/HMOX1/PRDX3/AXL/PRDX5/RPS3/HBA2/NQO1/FOXO1/DHFR/KCNMB1/CBX8/GSTO1/MAP3K5/PINK1/NXN/EZH2/FANCC/TIMELESS/IPCEF1/TP53INP1/ARG1/GPX4/PARK7/STK25/PPP5C/TXNRD3/PRKCE/GSTM1/ECT2/MPO/ZC3H12A/HBG1/DDX11/PRDX6/GSTT1/HBB/MGST2/NNT/MGST3/GSTK1/CCS/CCL7/TXNRD2/ABTB2/NET1/GSTZ1/PDGFB/SESN2/AKR1A1/PRDX1/BAD/ACTB/SIRT1	74
BP	GO:0031122	cytoplasmic microtubule organization	19/4749	53/18670	0.06008	0.246	0.2001	FSD1/NUMA1/STMN3/TUBGCP2/EZR/FIGNL1/DVL1/TUBG2/IFT172/CHP1/HOOK2/WDR73/CCDC88B/KATNAL2/TUBG1/SLAIN2/TUBGCP5/KIF19/TUBGCP3	19
BP	GO:0032715	negative regulation of interleukin-6 production	19/4749	53/18670	0.06008	0.246	0.2001	KLF2/IL10/PTPN6/SIRPA/TNF/CD200/TLR4/FOXP3/ARRB1/HAVCR2/IRAK3/GBA/IL27RA/C1QTNF3/SYT11/NLRC3/ZC3H12A/RABGEF1/GHRL	19
BP	GO:0050702	interleukin-1 beta secretion	19/4749	53/18670	0.06008	0.246	0.2001	NLRP3/TLR8/HK1/LGALS9/PML/HMGB1/TLR4/LILRA2/CCL3/ABCA1/NOD2/TLR6/ZC3H12A/LILRA5/RIPK2/CARD8/FZD5/TRIM16/P2RX7	19
BP	GO:0035567	non-canonical Wnt signaling pathway	47/4749	150/18670	0.06039	0.246	0.2001	RAC1/VANGL1/NKD1/TIAM1/CTHRC1/PSMD8/TNRC6B/CAMK2A/DVL3/SFRP4/PSMD1/PSMD2/FZD6/PTK7/PSMF1/SMURF1/TCF7L2/DVL1/PSMD9/AP2S1/PSMA5/WNT7A/FZD8/RNF213/PSMB7/PSMD5/PSME2/SFRP1/IFT80/RSPO3/PSMB5/MLLT3/FZD9/PSMB4/PSMA3/MED12/PARD6A/FZD5/PSMD10/PLCB1/CDC42/PSMB1/PSMD7/PSMB3/PSMC5/PDE6B/PSMD11	47
BP	GO:0001783	B cell apoptotic process	10/4749	24/18670	0.06059	0.246	0.2001	AURKB/IL10/BCL6/BAX/TNFRSF21/BTK/CD74/BAK1/SLC39A10/MIR17HG	10
BP	GO:0006862	nucleotide transport	10/4749	24/18670	0.06059	0.246	0.2001	SLC25A23/ABCD1/SLC25A25/SLC35B2/SLC25A5/SLC25A36/SLC33A1/SLC25A42/SLC25A4/P2RX7	10
BP	GO:0007141	male meiosis I	10/4749	24/18670	0.06059	0.246	0.2001	HSPA2/TRIP13/SLC2A8/BRCA2/TDRD9/DMC1/UBB/REC8/UBR2/DMRTC2	10
BP	GO:0031579	membrane raft organization	10/4749	24/18670	0.06059	0.246	0.2001	ANXA2P2/GSN/ANXA2/MYADM/FA2H/PPT1/PTPRC/RFTN1/FLOT1/S100A10	10
BP	GO:0032925	regulation of activin receptor signaling pathway	10/4749	24/18670	0.06059	0.246	0.2001	SKI/DAND5/SMAD7/FGF9/ZC3H3/LEMD3/FKBP1A/ACVR2B/DACT2/CER1	10
BP	GO:0045606	positive regulation of epidermal cell differentiation	10/4749	24/18670	0.06059	0.246	0.2001	VDR/NOTCH1/PTCH1/NUMA1/SFN/SFRP4/CYP27B1/IL20/TRIM16/NME2	10
BP	GO:0046639	negative regulation of alpha-beta T cell differentiation	10/4749	24/18670	0.06059	0.246	0.2001	BCL6/CBFB/TNFSF4/HMGB1/FOXP3/IL4R/SMAD7/HLX/ZC3H12A/JAK3	10
BP	GO:0046697	decidualization	10/4749	24/18670	0.06059	0.246	0.2001	VDR/LIF/PTGIS/SPP1/CTSB/CYP27B1/BSG/GHRL/PPARD/MAPK1	10
BP	GO:0051220	cytoplasmic sequestering of protein	10/4749	24/18670	0.06059	0.246	0.2001	IL10/NFKBIE/TONSL/SRI/PKD2/NFKBIA/NFKBIL1/GOPC/PSMD10/MXI1	10
BP	GO:1902410	mitotic cytokinetic process	10/4749	24/18670	0.06059	0.246	0.2001	KIF20A/CEP55/KIF20B/CHMP2B/CHMP1A/CHMP2A/MITD1/NUP62/CHMP3/KLHDC8B	10
BP	GO:0001325	formation of extrachromosomal circular DNA	7/4749	15/18670	0.06149	0.246	0.2001	EXO1/TERF1/XRCC3/DNA2/WRN/ERCC1/TERF2	7
BP	GO:0009415	response to water	7/4749	15/18670	0.06149	0.246	0.2001	NTRK1/CD9/COL18A1/PKD2/AQP2/ATP2B4/LRP11	7
BP	GO:0010561	negative regulation of glycoprotein biosynthetic process	7/4749	15/18670	0.06149	0.246	0.2001	HBEGF/ITM2A/ACOT8/ACER2/ITM2B/ITM2C/JAK3	7
BP	GO:0018158	protein oxidation	7/4749	15/18670	0.06149	0.246	0.2001	GPX1/PRDX3/SUMF1/PARK7/LOXL1/CHCHD4/TRABD2B	7
BP	GO:0030852	regulation of granulocyte differentiation	7/4749	15/18670	0.06149	0.246	0.2001	TRIB1/CEACAM1/ZBTB46/ADIPOQ/TESC/CUL4A/RARA	7
BP	GO:0032105	negative regulation of response to extracellular stimulus	7/4749	15/18670	0.06149	0.246	0.2001	KANK2/BBS2/NENF/CCK/MKKS/NUCB2/NPFF	7
BP	GO:0032108	negative regulation of response to nutrient levels	7/4749	15/18670	0.06149	0.246	0.2001	KANK2/BBS2/NENF/CCK/MKKS/NUCB2/NPFF	7
BP	GO:0032352	positive regulation of hormone metabolic process	7/4749	15/18670	0.06149	0.246	0.2001	EGR1/IL1B/TNF/ADM/POR/RDH10/GATA3	7
BP	GO:0034134	toll-like receptor 2 signaling pathway	7/4749	15/18670	0.06149	0.246	0.2001	TIRAP/TLR2/IRAK1/TLR6/CYBA/RIPK2/PJA2	7
BP	GO:0035067	negative regulation of histone acetylation	7/4749	15/18670	0.06149	0.246	0.2001	TWIST1/SPI1/FOXP3/TAF7/CTBP1/ZNF451/SIRT1	7
BP	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	7/4749	15/18670	0.06149	0.246	0.2001	SPRED2/ZNF385A/PMAIP1/MSX1/RPL26/ATR/ATM	7
BP	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	7/4749	15/18670	0.06149	0.246	0.2001	TWIST1/DYRK3/SNAI1/CD74/CD44/PSMD10/SIRT1	7
BP	GO:0051044	positive regulation of membrane protein ectodomain proteolysis	7/4749	15/18670	0.06149	0.246	0.2001	IL1B/FURIN/SNX9/TNF/SNX33/TNFRSF1B/ADAM9	7
BP	GO:0051299	centrosome separation	7/4749	15/18670	0.06149	0.246	0.2001	AURKA/NEK2/KIF11/CHEK1/NSFL1C/MAP9/NUP62	7
BP	GO:0090656	t-circle formation	7/4749	15/18670	0.06149	0.246	0.2001	EXO1/TERF1/XRCC3/DNA2/WRN/ERCC1/TERF2	7
BP	GO:0090737	telomere maintenance via telomere trimming	7/4749	15/18670	0.06149	0.246	0.2001	EXO1/TERF1/XRCC3/DNA2/WRN/ERCC1/TERF2	7
BP	GO:2000402	negative regulation of lymphocyte migration	7/4749	15/18670	0.06149	0.246	0.2001	CD200/ADTRP/GCSAM/CCL2/IL27RA/PADI2/KLRK1	7
BP	GO:0050867	positive regulation of cell activation	114/4749	394/18670	0.06168	0.246	0.2001	EGR3/EBI3/IL1B/CD86/IL18/CD276/IL21/CDKN1A/NR4A3/NLRP3/DUSP10/IL10/CD83/CD80/RAC1/TTBK1/PDCD1/PTPN6/BCL6/CBFB/SIRPA/TIRAP/TNFSF4/TFRC/CLEC7A/LGALS9/HMGB1/TNFRSF4/IL2RA/TLR4/BTN2A2/LILRA2/FOXP3/GAB2/CTLA4/IL4R/DOCK8/TOX/CCR2/SRC/HLA-G/TP53BP1/LILRB4/BTK/CCL3/HAVCR2/AXL/CD74/PAK1/CD177/CD1D/GRAP2/RPS3/EFNB1/HLX/LGALS1/PPP2R3C/CCL2/PNP/PAK3/DNAJA3/HLA-DPA1/PTPRC/CYLD/CORO1A/HLA-E/CD47/AIF1/AP3D1/SART1/NOD2/LILRB2/IL12RB1/THY1/TLR6/CD46/CLEC4D/IL7R/HLA-DMB/TNFSF9/PDCD1LG2/IL7/LILRA5/CD3E/IL13/CCDC88B/CARD11/LAMP1/TNFSF13/IL4/RIPK2/TYROBP/CD6/MAD2L2/HLA-DPB1/TRAF6/SPHK2/VNN1/ATP11C/TNFSF11/SLC39A10/TGFB1/CDC42/JAK3/RARA/HHLA2/KLRK1/ZAP70/GATA3/PTAFR/BAD/FYN/PAK2/IL23A	114
BP	GO:0000470	maturation of LSU-rRNA	9/4749	21/18670	0.06182	0.246	0.2001	RPL10A/RPL35/RPL7/NOL9/ZNHIT3/BOP1/WDR12/RPL7A/URB1	9
BP	GO:0006293	nucleotide-excision repair, preincision complex stabilization	9/4749	21/18670	0.06182	0.246	0.2001	DDB2/ERCC5/ERCC2/GTF2H2/GTF2H1/GTF2H5/XPA/CUL4A/ERCC1	9
BP	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion	9/4749	21/18670	0.06182	0.246	0.2001	DDB2/ERCC5/ERCC2/GTF2H2/GTF2H1/GTF2H5/XPA/CUL4A/ERCC1	9
BP	GO:0006450	regulation of translational fidelity	9/4749	21/18670	0.06182	0.246	0.2001	RPS5/RPS9/PRORSD1P/LARS2/DTD2/EIF2S3/VARS2/HSPA14/YRDC	9
BP	GO:0010310	regulation of hydrogen peroxide metabolic process	9/4749	21/18670	0.06182	0.246	0.2001	RAC1/NOXA1/CTNS/STAT3/PINK1/RAC2/ZNF205/NNT/FYN	9
BP	GO:0035590	purinergic nucleotide receptor signaling pathway	9/4749	21/18670	0.06182	0.246	0.2001	P2RY13/P2RX1/GPR34/P2RX6/P2RY10/P2RX5/P2RY1/PTAFR/P2RX7	9
BP	GO:0035743	CD4-positive, alpha-beta T cell cytokine production	9/4749	21/18670	0.06182	0.246	0.2001	IL1B/IL18/NLRP3/IL1R1/RSAD2/ARG1/IL18R1/IL4/GATA3	9
BP	GO:0039531	regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway	9/4749	21/18670	0.06182	0.246	0.2001	SEC14L1/NPLOC4/BIRC3/C1QBP/TSPAN6/ANKRD17/ZCCHC3/USP17L2/TRIM15	9
BP	GO:0042135	neurotransmitter catabolic process	9/4749	21/18670	0.06182	0.246	0.2001	ABAT/GLDC/SARDH/BHMT/POR/ALDH7A1/AMT/ALDH5A1/SLC44A1	9
BP	GO:0043153	entrainment of circadian clock by photoperiod	9/4749	21/18670	0.06182	0.246	0.2001	PML/PPP1CB/CRY1/PER2/CRTC1/BHLHE40/RBM4B/MTA1/PER3	9
BP	GO:0046132	pyrimidine ribonucleoside biosynthetic process	9/4749	21/18670	0.06182	0.246	0.2001	DHODH/NME4/UPRT/NME3/CMPK1/CTPS2/UCK2/NME9/NME2	9
BP	GO:0046827	positive regulation of protein export from nucleus	9/4749	21/18670	0.06182	0.246	0.2001	IL1B/GTSE1/CAMK1/YWHAE/RBM22/SFN/TCF7L2/EMD/BAG3	9
BP	GO:0051412	response to corticosterone	9/4749	21/18670	0.06182	0.246	0.2001	CDKN1A/FOSL1/FOSB/NTRK3/HSD3B2/AANAT/NEFL/FOS/CCND1	9
BP	GO:0071459	protein localization to chromosome, centromeric region	9/4749	21/18670	0.06182	0.246	0.2001	AURKB/CENPA/TTK/CDK1/CDT1/NDC80/BOD1/CHAMP1/TRAPPC12	9
BP	GO:1900016	negative regulation of cytokine production involved in inflammatory response	9/4749	21/18670	0.06182	0.246	0.2001	SIRPA/ABCD1/IL1R2/PDCD4/ABCD2/C5orf30/NLRC3/ZC3H12A/CHID1	9
BP	GO:2000114	regulation of establishment of cell polarity	9/4749	21/18670	0.06182	0.246	0.2001	KIF20B/GSN/DOCK8/WDPCP/KRIT1/RUFY3/BCAS3/CDH5/GATA3	9
BP	GO:0045124	regulation of bone resorption	15/4749	40/18670	0.06199	0.246	0.2001	CSF1R/TFRC/SPP1/SRC/PPARGC1B/S1PR1/PRKCA/PLEKHM1/CA2/BGLAP/TNFRSF11B/TMEM119/TNFSF11/TMEM64/P2RX7	15
BP	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	15/4749	40/18670	0.06199	0.246	0.2001	BAX/CXCL10/TRPC1/SRI/PKD2/HTT/GSTO1/CXCL9/DRD1/THY1/CD19/NTSR1/LACRT/IL13/F2R	15
BP	GO:0071526	semaphorin-plexin signaling pathway	15/4749	40/18670	0.06199	0.246	0.2001	RAC1/PLXNB2/SEMA4C/PLXNB1/SEMA7A/SEMA3G/SEMA6C/PLXNA1/SEMA6B/PLXND1/SEMA3B/SEMA5B/SEMA4D/ARHGDIA/SEMA5A	15
BP	GO:0098534	centriole assembly	15/4749	40/18670	0.06199	0.246	0.2001	STIL/WDR62/PLK4/PLK2/CENPJ/CDK2/KAT2A/MDM1/CEP152/C10orf90/ALMS1/CETN2/CHMP2A/CEP72/NUP62	15
BP	GO:0030308	negative regulation of cell growth	57/4749	186/18670	0.06206	0.246	0.2001	GNG4/CDKN1A/PPARG/BCL11A/BCL6/CDK5/ENO1/SPP1/PPP2R1A/PML/SEMA4C/SEMA7A/ING1/HSPA1A/CDKN2C/NAIF1/PSRC1/MSX1/SEMA3G/SEMA6C/BST2/PPT1/PAK1/SEMA6B/SMARCA4/FGF13/ARHGAP4/ADIPOR2/PPP2CA/CDKN2A/ADIPOR1/CYP27B1/SH3BP4/SEMA3B/ADAM15/SEMA5B/GSK3A/CDKN2AIP/SFRP1/CRLF3/PTPRS/DCBLD2/SEMA4D/BMP10/SPHK2/EAF2/IP6K2/PPP1R9B/PPARD/TGFB1/SEMA5A/NDUFA13/RTN4R/DNAJB2/SESN2/OSGIN2/SIRT1	57
BP	GO:0002902	regulation of B cell apoptotic process	8/4749	18/18670	0.06228	0.246	0.2001	AURKB/IL10/BCL6/BAX/BTK/CD74/SLC39A10/MIR17HG	8
BP	GO:0007221	positive regulation of transcription of Notch receptor target	8/4749	18/18670	0.06228	0.246	0.2001	NOTCH1/DLGAP5/MAML1/MAML2/RBPJ/PLXND1/STAT1/PBX1	8
BP	GO:0015865	purine nucleotide transport	8/4749	18/18670	0.06228	0.246	0.2001	SLC25A23/ABCD1/SLC25A25/SLC35B2/SLC25A5/SLC33A1/SLC25A42/SLC25A4	8
BP	GO:0016446	somatic hypermutation of immunoglobulin genes	8/4749	18/18670	0.06228	0.246	0.2001	EXO1/MSH6/PMS2P1/POLQ/AICDA/PMS2P5/SAMHD1/POLM	8
BP	GO:0031998	regulation of fatty acid beta-oxidation	8/4749	18/18670	0.06228	0.246	0.2001	TWIST1/MTOR/ABCD1/ABCD2/TYSND1/CNR1/CPT1A/ACACB	8
BP	GO:0032693	negative regulation of interleukin-10 production	8/4749	18/18670	0.06228	0.246	0.2001	TNFRSF21/FOXP3/IDO1/PDCD1LG2/TYROBP/DLL1/JAK3/IL23A	8
BP	GO:0036035	osteoclast development	8/4749	18/18670	0.06228	0.246	0.2001	ANXA2P2/LRRK1/ANXA2/SRC/FAM20C/TYROBP/TNFSF11/SLC9B2	8
BP	GO:0039535	regulation of RIG-I signaling pathway	8/4749	18/18670	0.06228	0.246	0.2001	SEC14L1/NPLOC4/BIRC3/C1QBP/ANKRD17/ZCCHC3/USP17L2/TRIM15	8
BP	GO:0042095	interferon-gamma biosynthetic process	8/4749	18/18670	0.06228	0.246	0.2001	EBI3/IL18/CD276/IL21/TLR8/CLEC7A/FOXP3/ZFPM1	8
BP	GO:0042772	DNA damage response, signal transduction resulting in transcription	8/4749	18/18670	0.06228	0.246	0.2001	FOXM1/CDKN1A/ZNF385A/BRCA2/RPL26/MUC1/MAD2L2/CHEK2	8
BP	GO:0045056	transcytosis	8/4749	18/18670	0.06228	0.246	0.2001	MFSD2A/SRC/LRPAP1/PIGR/FCGRT/LRP1/PTAFR/USO1	8
BP	GO:0045780	positive regulation of bone resorption	8/4749	18/18670	0.06228	0.246	0.2001	TFRC/SPP1/PPARGC1B/PRKCA/PLEKHM1/CA2/TNFSF11/TMEM64	8
BP	GO:0046852	positive regulation of bone remodeling	8/4749	18/18670	0.06228	0.246	0.2001	TFRC/SPP1/PPARGC1B/PRKCA/PLEKHM1/CA2/TNFSF11/TMEM64	8
BP	GO:0060749	mammary gland alveolus development	8/4749	18/18670	0.06228	0.246	0.2001	VEGFA/SOCS2/FOXB1/TPH1/DDR1/ESR1/TNFSF11/CCND1	8
BP	GO:0061377	mammary gland lobule development	8/4749	18/18670	0.06228	0.246	0.2001	VEGFA/SOCS2/FOXB1/TPH1/DDR1/ESR1/TNFSF11/CCND1	8
BP	GO:1902165	regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	8/4749	18/18670	0.06228	0.246	0.2001	ZNF385A/RPL26/CD74/TAF9B/MUC1/BCL2L12/CD44/SIRT1	8
BP	GO:1903019	negative regulation of glycoprotein metabolic process	8/4749	18/18670	0.06228	0.246	0.2001	HBEGF/ITM2A/CST3/ACOT8/ACER2/ITM2B/ITM2C/JAK3	8
BP	GO:2000757	negative regulation of peptidyl-lysine acetylation	8/4749	18/18670	0.06228	0.246	0.2001	TWIST1/SPI1/FOXP3/TAF7/CTBP1/ZNF451/HINT2/SIRT1	8
BP	GO:0032612	interleukin-1 production	37/4749	115/18670	0.06232	0.246	0.2001	EGR1/IL1B/NLRP3/IL10/ACP5/TLR8/HK1/SIRPA/CLEC7A/CEACAM1/LGALS9/PML/HMGB1/TLR4/S100A13/LILRA2/IL1R2/CCL3/HAVCR2/CD33/ABCA1/NOD2/TLR6/MNDA/MR1/ZC3H12A/LILRA5/IFI16/GHRL/RIPK2/F2R/TYROBP/CARD8/FZD5/TRIM16/P2RX7/CX3CR1	37
BP	GO:0021700	developmental maturation	84/4749	284/18670	0.06272	0.2474	0.2013	KIF14/VEGFA/IL21/CDKN1A/PPARG/KLF2/AURKA/BCL11A/TRIP13/CDC20/CBFB/CLEC7A/C1QL1/PPP2R1A/TYMS/YWHAZ/PLXNB1/ASCL1/CEND1/BRCA2/MTOR/DCHS1/WNT10B/CCR6/CCNB1/MYO5A/BLOC1S6/FBXO5/SYT4/RAB32/PABPC1L/BTK/DMC1/AXL/RBPJ/LYL1/FAM20C/RUNX2/S1PR1/PICK1/TBX6/SCARF1/AP3D1/ELSPBP1/SEZ6L/FEM1B/DDIT3/SLC26A6/MAEA/SOX8/NFIA/ERCC2/REC8/SNX19/RECK/EPAS1/IRX5/RAB38/PAEP/SNAPIN/BFSP2/B4GALT5/SIRT2/PCSK4/NOM1/C1QA/TDRD5/SEMA4D/MBTPS2/NEFL/FZD5/XYLT1/CATSPER2/ANKRD17/LHX6/POU2F2/NSUN2/CDC25B/CDH5/GATA3/CX3CR1/SYBU/DLG4/RAC3	84
BP	GO:0051648	vesicle localization	90/4749	306/18670	0.06293	0.2481	0.2018	MYO7A/ADORA2A/KIF23/SEC13/KIF1C/RIMS3/CDK5/BBS2/GORASP1/SEC24D/SYN1/MCFD2/NCS1/CHRNA5/F5/STX11/STX5/MYO5A/BLOC1S6/GRIPAP1/SEC16A/P2RX1/SYT4/SNAP47/HTR2A/BLOC1S1/CAMK2A/VPS33B/CNIH2/SNAP29/PFN2/HTT/SLC2A4/FYCO1/BLOC1S4/APBA2/STX1B/ANKRD28/PINK1/TBC1D20/CLASP2/ACTN4/DVL1/AP3D1/SCRIB/CEP19/STX19/MKKS/DRD1/TMED9/SNAP23/DTNBP1/RAB27A/WNT7A/PPFIA3/CNR1/ASIP/FMR1/GBF1/TMED10/SYT11/CTSZ/WDR11/AP3M2/ERC2/BRSK2/SNAPIN/NAPB/DNM1/STX2/DOC2B/TRAPPC4/PRKCB/P2RY1/SYN2/RAB1A/CACNB2/FBXL20/KIAA1107/AP1AR/PPP6C/AP3B2/SV2A/PEF1/P2RX7/SYBU/PPP6R1/RAB1B/TRIM9/USO1	90
BP	GO:1903034	regulation of response to wounding	55/4749	179/18670	0.06305	0.2484	0.2021	HBEGF/CD109/CDKN1A/DUSP10/PTPRF/IL10/KLF4/PDGFA/PLAUR/GRN/CNTF/HPSE/CLEC7A/ANXA2P2/CEACAM1/SPP1/CD9/TNFRSF12A/PROS1/TMPRSS6/TLR4/PROC/PLAU/SERPINE1/MTOR/ADTRP/RGMA/ANXA2/VKORC1/PLAT/ABAT/NTRK3/PRKCA/CLASP2/ANXA5/SCARF1/VTN/LRP1/ENPP4/CRK/PRKCE/KLKB1/TBXA2R/SERPING1/INSL3/F3/CD34/MYH9/F2R/PTPRS/SIGLEC10/PPARD/RTN4R/PDGFB/TFPI	55
BP	GO:0017156	calcium ion regulated exocytosis	48/4749	154/18670	0.06313	0.2485	0.2022	NOTCH1/ADORA2A/RIMS3/CDK5/SYN1/NCS1/CHRNA5/HYAL3/STX11/BLOC1S6/P2RX1/SYT4/SNAP47/HTR2A/CAMK2A/SNAP29/PFN2/APBA2/STX1B/DVL1/SCRIB/STX19/DRD1/SNAP23/DTNBP1/GNAI2/WNT7A/PPFIA3/CNR1/CHP1/FMR1/SYT11/VAMP3/ERC2/SNAPIN/NAPB/STX2/DOC2B/PRKCB/P2RY1/SYN2/ARHGAP17/CACNB2/FBXL20/SYT15/SV2A/P2RX7/TRIM9	48
BP	GO:0033013	tetrapyrrole metabolic process	21/4749	60/18670	0.06332	0.249	0.2026	ABCC1/CPOX/TSPO/FXN/MMAB/HMOX1/IBA57/TCN1/TCN2/CLYBL/RSAD1/CUBN/MMACHC/MTRR/BDH2/BLVRA/HMOX2/PPOX/CTRB1/MTR/LMBRD1	21
BP	GO:0046794	transport of virus	21/4749	60/18670	0.06332	0.249	0.2026	SEC13/KPNA2/NUP98/BST2/UBB/NUP153/RPS27A/UBA52/NUP88/FMR1/KPNA3/POM121C/NUP205/RAE1/NUP50/NUP93/NUP35/AAAS/NUP62/SEH1L/TRIM15	21
BP	GO:2000779	regulation of double-strand break repair	26/4749	77/18670	0.06352	0.2494	0.2029	TWIST1/FOXM1/PML/SIRT6/RAD51/RAD51AP1/NUDT16/PARPBP/RMI2/DTX3L/TP53BP1/POLQ/MAGEF1/TFIP11/FIGNL1/TIMELESS/RECQL5/CHEK1/WRAP53/AUNIP/DDX11/MAD2L2/HELB/OGG1/WAS/MGMT	26
BP	GO:0010718	positive regulation of epithelial to mesenchymal transition	18/4749	50/18670	0.06363	0.2494	0.2029	TWIST1/IL1B/NOTCH1/TGFB1I1/MTOR/SNAI1/ALX1/TIAM1/SDCBP/TGFB3/WWTR1/JAG1/TCF7L2/EZH2/ZNF703/GLIPR2/AXIN2/TGFB1	18
BP	GO:0034656	nucleobase-containing small molecule catabolic process	18/4749	50/18670	0.06363	0.2494	0.2029	ENTPD1/TYMP/APOBEC3H/ENTPD5/APOBEC3B/NUDT16/NUDT1/HPRT1/ENTPD2/PNP/ADPRM/AICDA/ENPP4/DPYD/GSK3A/ENTPD4/NT5E/GALT	18
BP	GO:0046854	phosphatidylinositol phosphorylation	18/4749	50/18670	0.06363	0.2494	0.2029	TTC7A/SOCS2/TTC7B/SOCS3/TMEM150A/PIKFYVE/IMPA2/PIP5K1B/PI4K2A/SLA2/INPP1/FAM126B/PIK3C3/IP6K1/PIP4K2A/IP6K2/PIP4K2B/PIP5K1A	18
BP	GO:0097035	regulation of membrane lipid distribution	18/4749	50/18670	0.06363	0.2494	0.2029	ABCC1/ATP11A/PRELID1/ATP8B4/PLSCR4/TLCD1/ABCA1/KCNN4/TMEM30A/ABCB4/PLSCR2/ATP10A/ATP8B3/ATP10D/ARV1/ATP11C/ANO4/P2RX7	18
BP	GO:0140013	meiotic nuclear division	53/4749	172/18670	0.06402	0.2508	0.2041	ESPL1/LIF/ASPM/BUB1B/TTK/TOP2A/AURKA/HSPA2/TRIP13/CDC20/PTTG1/BUB1/KIF18A/RAD54L/PPP2R1A/SYCE3/NUF2/SLC2A8/FBXO43/BRCA2/UBE2B/PLK1/RAD51/MSX1/TDRD9/CKS2/FBXO5/DMC1/UBB/MND1/CCNE2/TERF1/TAF1L/HELQ/FIGNL1/NCAPH/REC8/STAG3/EME1/KLHDC3/SYCE2/SIRT2/NCAPH2/UBR2/DMRTC2/ASZ1/ANKRD31/ATM/MLH3/PLCB1/RNF212/CDC25B/RAD54B	53
BP	GO:0060759	regulation of response to cytokine stimulus	58/4749	190/18670	0.06434	0.2519	0.205	IRF7/PPARG/IL1R1/KLF4/PTPN6/IL1RN/TREX1/CBFB/RFFL/TNF/CSF1/HSPA1A/TLR4/NOL3/PTPN1/AGPAT2/MMP12/IL1R2/PARP14/SOCS3/TRAIP/CLIP3/AXL/CD74/IRAK3/PTPRC/SIGIRR/CD300LF/PIAS1/CYLD/ABCE1/TLR2/SCRIB/TRIM44/TXK/IRAK1/ARG1/SUMO1/CREBRF/TRAF1/IRF3/SAMHD1/IL7/RABGEF1/BIRC3/CNOT7/YTHDF3/PADI2/TRAF2/IFNGR1/PIAS4/ADIPOQ/RIPK2/STAT1/CARD8/ZNF675/SPATA2/JAK1	58
BP	GO:0051492	regulation of stress fiber assembly	28/4749	84/18670	0.06467	0.2529	0.2058	SDC4/RAC1/NF2/FHOD1/MTOR/BAG4/ARHGEF5/PTGER4/TGFB3/PAK1/PFN2/S1PR1/STMN1/CLASP2/CD47/LIMCH1/S100A10/MKKS/ARAP1/LIMK1/SH3PXD2B/ALMS1/SFRP1/TPM1/SORBS3/WASF2/CDC42/WAS	28
BP	GO:1902803	regulation of synaptic vesicle transport	28/4749	84/18670	0.06467	0.2529	0.2058	ADORA2A/RIMS3/CDK5/SYN1/NCS1/CHRNA5/P2RX1/SYT4/HTR2A/CAMK2A/CNIH2/PFN2/SLC2A4/APBA2/STX1B/PINK1/DVL1/DRD1/DTNBP1/WNT7A/CNR1/FMR1/SNAPIN/NAPB/PRKCB/P2RY1/CACNB2/FBXL20	28
BP	GO:0006414	translational elongation	42/4749	133/18670	0.06506	0.2543	0.2069	MRPL37/MRPL28/MRPL51/MRPS36/RPLP2/MRPL22/DPH5/MRPL18/MRPS5/MRPS18C/MRPS11/EEF1B2/MRPS6/ZNF598/DPH1/TRNAU1AP/MRPL20/MRPL50/MRPL36/MRPS2/EEF1A1/MRPL35/MRPL27/MRPL15/MRPS25/MRPL34/MRPS14/EEF1A2/MRPL13/PTCD3/GADD45GIP1/MRPL10/DNAJC24/MRPL54/DAP3/MRPL2/MRPL39/SECISBP2L/MRPL43/TUFM/MRPL48/GFM1	42
BP	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion	14/4749	37/18670	0.06526	0.2543	0.2069	DDB2/UBB/RFC2/RPS27A/UBA52/POLD4/ERCC5/ERCC2/GTF2H2/GTF2H1/GTF2H5/XPA/CUL4A/ERCC1	14
BP	GO:0030201	heparan sulfate proteoglycan metabolic process	14/4749	37/18670	0.06526	0.2543	0.2069	SULF2/HS3ST3B1/HS3ST3A1/HPSE/GPC1/B3GAT3/CSGALNACT1/TCF7L2/B3GALT6/EXT1/EXTL2/HS6ST1/HS3ST4/XYLT1	14
BP	GO:0033280	response to vitamin D	14/4749	37/18670	0.06526	0.2543	0.2069	VDR/KANK2/FES/SPP1/CXCL10/TRIM25/GDAP1/PIM1/PHEX/CASR/CYP27B1/BGLAP/SFRP1/TGFB1	14
BP	GO:0038083	peptidyl-tyrosine autophosphorylation	14/4749	37/18670	0.06526	0.2543	0.2069	VEGFA/NTRK1/HCK/SLA/BLK/SRC/BTK/IGF1R/PTK6/TXK/DDR1/ITK/INSR/FYN	14
BP	GO:0043114	regulation of vascular permeability	14/4749	37/18670	0.06526	0.2543	0.2069	VEGFA/ADORA2A/C2CD4B/CEACAM1/SRC/ARHGAP35/BDKRB2/TACR2/ADM/BCR/TGFB1/CDH5/C2CD4A/PTP4A3	14
BP	GO:0031503	protein-containing complex localization	83/4749	281/18670	0.06572	0.2559	0.2082	TNFAIP2/BIRC5/CEP112/SEC13/U2AF1/HIP1/SFPQ/TTC30A/NUP98/SMG5/POLDIP3/WDR34/SMAD7/GRIPAP1/IWS1/DYNLRB1/RNPS1/SNAP47/RPS15/ENY2/SRSF4/ICK/CNIH2/NUP153/UPF1/SYNJ2BP/TERF1/MAGOHB/STX1B/EZR/ABCE1/ALKBH5/IFT122/CACNG3/AP3D1/SUPT6H/KLHL21/SCRIB/IFT172/NUP88/TTC21A/THOC3/KIF3C/IFT27/U2AF1L4/WDR60/POM121C/BBS12/ADAM22/WDR19/NUP205/RAE1/NUP50/DHX38/SDAD1/SNAPIN/MAGOH/IFT80/DNM1/CPSF1/TYROBP/SMG6/GLE1/ATR/CEP72/NUP93/DDX19A/CDC40/RALB/ARL3/NUP35/ATM/AAAS/TTC26/NCBP2/CLUAP1/NUP62/TNPO1/SEH1L/YTHDC1/DLG4/TERF2/NXF3	83
BP	GO:0006986	response to unfolded protein	54/4749	176/18670	0.0665	0.2587	0.2104	HSPA2/CHAC1/ATP6V0D1/DNAJA1/ATF3/HSPA5/CREB3L2/SERP2/HSPA1A/DERL1/BAX/TPP1/DNAJB5/PTPN1/ZBTB17/LMNA/SYVN1/HSPA9/VCP/HERPUD1/ATF4/ASNS/CTH/CCL2/EXTL2/PARP16/BAK1/DDIT3/CREBRF/JKAMP/EDEM2/BAG3/FICD/GSK3A/HSPA6/KLHDC3/YIF1A/DDX11/EIF2AK3/ERN1/SERP1/CANX/HSPA1L/RNF121/HSPA14/MBTPS2/PPP1R15A/DNAJB4/THBS4/HERPUD2/TMEM33/DNAJB2/CCND1/SHC1	54
BP	GO:0050796	regulation of insulin secretion	54/4749	176/18670	0.0665	0.2587	0.2104	IL1B/RAC1/PIM3/SLC16A1/TNF/BLK/TIAM1/ABAT/ARRB1/ENY2/C2CD2L/SRI/ENHO/PER2/CASR/TCF7L2/PRKCA/TRPM4/NADK/OXCT1/PFKFB2/PSMD9/LRP1/CACNA2D2/SIRT3/CNR1/TFAP2B/ACVR1C/SLC25A5/PRKCE/SIDT2/LRP5L/ARNTL/GLUD1/BRSK2/SFRP1/GHRL/KCNG2/CPT1A/ARL2BP/SERP1/DOC2B/SLC25A4/PFKL/ARL2/NPFF/PPARD/SLC9B2/FFAR1/NDUFAF2/PDX1/GIPR/SYBU/BAD	54
BP	GO:0099504	synaptic vesicle cycle	59/4749	194/18670	0.06661	0.2589	0.2107	ADORA2A/CYFIP1/RIMS3/CDK5/SYN1/NCS1/CHRNA5/ACTG1/STX11/BLOC1S6/GRIPAP1/P2RX1/SYT4/SNAP47/HTR2A/CAMK2A/SNAP29/PFN2/STON2/SLC2A4/SH3GL1/APBA2/STXBP5/STX1B/DVL1/AP3D1/SCRIB/STX19/DRD1/SNAP23/DTNBP1/WNT7A/PPFIA3/CNR1/FMR1/DNAJC6/SYT11/ERC2/BRSK2/SNAPIN/NAPB/NLGN4Y/DNM1/EEA1/STX2/CANX/DOC2B/PRKCB/PACSIN1/P2RY1/ARF6/SYN2/CACNB2/FBXL20/KIAA1107/SV2A/P2RX7/TRIM9/ACTB	59
BP	GO:1903169	regulation of calcium ion transmembrane transport	47/4749	151/18670	0.06671	0.2591	0.2108	GEM/HSPA2/PTPN6/SESTD1/YWHAE/TSPAN13/JSRP1/BAX/CXCL10/TRPC1/MYO5A/REM1/PDE4D/ATP2A1/KCNE3/PDE4B/SRI/PKD2/HTT/GPR35/ATP1B1/GSTO1/REM2/CORO1A/STAC3/CXCL9/DRD1/FKBP1A/STAC/THY1/CD19/SUMO1/NTSR1/FMR1/PRKCE/CYBA/LACRT/IL13/CAMK2D/PRNP/F2R/AHNAK/CACNB2/TMC2/EHD3/TGFB1/FYN	47
BP	GO:0051260	protein homooligomerization	102/4749	351/18670	0.06678	0.2593	0.2109	ACPP/SLC1A5/SLC1A1/MARCKS/IKZF4/DCTPP1/ALOX5AP/TIFA/DGKD/PFKP/TP63/KCTD17/TK1/SKI/DERL1/BAX/RAD51/FSD1/CRTC2/NACC1/RIPK3/SRC/HMOX1/KCTD5/P2RX1/TGM2/TNFAIP1/PKM/LY6G5C/HLA-G/TP53BP1/PAM/VCP/BMF/CLU/MICU1/P2RX6/POLQ/HPRT1/KCNJ2/KCNA3/PKD2/CRTC1/CTH/TYSND1/BIK/TERF1/AQP2/BID/CD79B/TMEM120A/CRYAA/TRPM4/VASP/CLYBL/FLOT1/HSF4/GBA/RASEF/ARG1/TAF10/ILDR1/RXRA/KCTD1/RNF213/SYT11/ECT2/LNX1/KCTD21/SAMHD1/SCUBE1/DFFB/CD3E/ELAVL1/TRAF2/ALDOA/KCNG2/GNMT/EIF2AK3/PEX5/ADIPOQ/CPT1A/KCTD13/PRNP/KCNC4/KCND3/GOPC/ACACB/COLEC12/CHMP2A/RAD52/APC/ALDH9A1/THG1L/PFKL/TNFSF11/STOM/EHD3/ALDH5A1/KCND1/CRBN/EHD4	102
BP	GO:1903428	positive regulation of reactive oxygen species biosynthetic process	20/4749	57/18670	0.0672	0.2607	0.2121	IL1B/ICAM1/KLF2/KLF4/CLEC7A/TNF/TLR4/DDAH2/MTOR/CLU/PKD2/AIF1/RAB27A/TLR6/PARK7/ZNF205/CYBA/HBB/INSR/KLRK1	20
BP	GO:0002832	negative regulation of response to biotic stimulus	17/4749	47/18670	0.06738	0.2607	0.2121	TRIB1/CEACAM1/IL2RA/LILRA2/SEC14L1/HAVCR2/NPLOC4/SIGIRR/DEFB114/NFKBIL1/LACRT/SIRT2/C1QBP/TSPAN6/CARD8/HTRA1/SIGLEC11	17
BP	GO:0043303	mast cell degranulation	17/4749	47/18670	0.06738	0.2607	0.2121	NR4A3/FES/LGALS9/S100A13/GAB2/MILR1/IL4R/HMOX1/BTK/LAT/SNAP23/UNC13D/RAC2/RABGEF1/IL13/FER/SPHK2	17
BP	GO:0045023	G0 to G1 transition	17/4749	47/18670	0.06738	0.2607	0.2121	RBBP8/E2F1/UXT/RAD51/RYBP/CBX5/HLA-G/PHC3/EED/EZH2/TFDP2/MDM4/PCGF6/CHEK1/RRM2/MAX/BMI1	17
BP	GO:1900744	regulation of p38MAPK cascade	17/4749	47/18670	0.06738	0.2607	0.2121	IL1B/VEGFA/DUSP10/GADD45G/GADD45A/MAP3K5/EZR/CYLD/PHLPP1/MAP3K3/ZC3H12A/MINK1/EMC10/MIR181D/NCF1/PJA2/DUSP1	17
BP	GO:1903115	regulation of actin filament-based movement	17/4749	47/18670	0.06738	0.2607	0.2121	DSC2/RANGRF/MYLK2/RNF207/PDE4D/ATP2A1/KCNE3/PDE4B/SRI/KCNJ2/FGF13/TRPM4/MYBPC3/SUMO1/TNNC1/CAMK2D/GJA5	17
BP	GO:1905475	regulation of protein localization to membrane	57/4749	187/18670	0.0678	0.262	0.2131	TP73/SQSTM1/ITGA3/YWHAH/GPC1/CDK5/LGALS3/YWHAE/TP63/YWHAZ/TNF/E2F1/AKAP5/GSN/PMAIP1/RANGRF/GRIPAP1/RHOG/SFN/CLIP3/PLS1/PAK1/PTPN9/PDCD5/NMT1/LRP4/BID/SPTBN1/EZR/LRRC15/PRKCI/STAC3/TFDP2/LRP1/STAC/YWHAQ/CHP1/GPC2/EFCAB7/ERBB2/PRKCE/BCL2L1/VTI1B/PRNP/LDLRAP1/GOPC/FZD9/ARF6/STOM/TGFB1/CNST/GDI1/USP17L2/BAD/FYN/ACTB/SHISA7	57
BP	GO:0006520	cellular amino acid metabolic process	106/4749	366/18670	0.0678	0.262	0.2131	BCAT1/P4HA2/IL4I1/SLC6A6/SLC6A8/SERINC3/GAMT/RIMKLB/DDAH2/CTNS/SDS/BCKDK/MPST/CARNS1/TST/PFAS/GGT1/SMS/GLS2/ABAT/PSMD8/ATCAY/GLDC/OGDH/AMDHD1/PSMD1/PSMD2/MTHFS/SARDH/HMGCL/ATF4/GPT/ASNS/PSMF1/NARS2/CTH/NQO1/GCAT/OAZ3/MRI1/ENOSF1/DLST/MTHFD1/BHMT/PSMD9/ATP2B4/PSMA5/ARG1/PPA2/NAGS/PARK7/SEPHS1/YARS2/PSMB7/CKB/NAT8L/MTRR/MTAP/OAZ2/PSMD5/IDO1/DPYD/PSPH/LARS2/GLUD1/TPH1/MARS2/PSME2/FAH/GNMT/P4HTM/ENOPH1/PSMB5/HARS2/VARS2/BPHL/GCLC/HGD/AASDHPPT/HIBADH/HPDL/PSMB4/CTPS2/MTR/GPT2/PSMA3/ALDH7A1/AMT/OAZ1/PLOD3/NFS1/GSS/PSMD10/PPM1K/PSMB1/ALDH5A1/PSMD7/PSMB3/NIT2/GSTZ1/ADHFE1/PSMC5/ASNSD1/BHMT2/FARSA/PSMD11	106
BP	GO:0006409	tRNA export from nucleus	13/4749	34/18670	0.06861	0.2638	0.2146	SEC13/NUP98/NUP153/NUP88/POM121C/NUP205/RAE1/NUP50/NUP93/NUP35/AAAS/NUP62/SEH1L	13
BP	GO:0042533	tumor necrosis factor biosynthetic process	13/4749	34/18670	0.06861	0.2638	0.2146	IL10/BCL3/CLEC7A/TNFRSF8/CYBB/TLR4/CARD9/CCR2/GHRL/IL4/MAPKAPK2/TYROBP/CX3CR1	13
BP	GO:0042534	regulation of tumor necrosis factor biosynthetic process	13/4749	34/18670	0.06861	0.2638	0.2146	IL10/BCL3/CLEC7A/TNFRSF8/CYBB/TLR4/CARD9/CCR2/GHRL/IL4/MAPKAPK2/TYROBP/CX3CR1	13
BP	GO:0043094	cellular metabolic compound salvage	13/4749	34/18670	0.06861	0.2638	0.2146	TYMP/TK1/HPRT1/PNP/MRI1/BHMT/AMPD2/MTAP/APRT/AMPD3/ENOPH1/UCK2/BHMT2	13
BP	GO:0070050	neuron cellular homeostasis	13/4749	34/18670	0.06861	0.2638	0.2146	TYRO3/CDK5/CHMP2B/NCS1/P2RX1/CNR1/CHRNA1/CALB2/FGGY/P2RY1/MAP1A/CACNB2/DNAJB2	13
BP	GO:0070884	regulation of calcineurin-NFAT signaling cascade	13/4749	34/18670	0.06861	0.2638	0.2146	CHERP/TNF/SPPL3/MTOR/HOMER2/PTBP1/LMCD1/C10orf71/ATP2B4/CHP1/CAMTA1/LACRT/PRNP	13
BP	GO:0071431	tRNA-containing ribonucleoprotein complex export from nucleus	13/4749	34/18670	0.06861	0.2638	0.2146	SEC13/NUP98/NUP153/NUP88/POM121C/NUP205/RAE1/NUP50/NUP93/NUP35/AAAS/NUP62/SEH1L	13
BP	GO:0106056	regulation of calcineurin-mediated signaling	13/4749	34/18670	0.06861	0.2638	0.2146	CHERP/TNF/SPPL3/MTOR/HOMER2/PTBP1/LMCD1/C10orf71/ATP2B4/CHP1/CAMTA1/LACRT/PRNP	13
BP	GO:1903533	regulation of protein targeting	27/4749	81/18670	0.06869	0.264	0.2148	BNIP3L/CDK5/BAG4/USP36/SAE1/PAK1/BAP1/PDCD5/PARL/NUCB1/HPS4/PINK1/CHP1/ERBB2/RAC2/BAG3/GSK3A/RHOU/UBL5/PRNP/HSPA1L/FZD5/STOM/GDI1/USP17L2/SREBF2/FYN	27
BP	GO:0009914	hormone transport	94/4749	322/18670	0.06876	0.2641	0.2148	LIF/IL1B/SLCO4A1/ADORA2A/RAC1/IL1RN/PIM3/RAB11FIP1/SLC16A1/NMB/SPP1/TNF/ADRA2B/SCG5/BLK/FFAR2/MYO5A/TIAM1/ABAT/ARRB1/BTK/GNAS/ENY2/C2CD2L/SRI/CRY1/ENHO/PER2/CCKAR/FFAR3/CASR/TCF7L2/KDM5B/PRKCA/TRPM4/NADK/ANXA5/OXCT1/PFKFB2/PSMD9/LRP1/SNAP23/OSM/CACNA2D2/SIRT3/ILDR1/CNR1/C1QTNF3/PARK7/TFAP2B/RAB11FIP3/ACVR1C/SLC25A5/ACVR2B/SNX19/CAMK2G/PRKCE/TACR2/SIDT2/LRP5L/SOX11/ARNTL/GLUD1/BRSK2/SFRP1/ADM/GHRL/KCNG2/ADIPOQ/CPT1A/ARL2BP/SLC16A10/RAB11FIP5/SERP1/DOC2B/CHRNA3/FAM3B/P2RY1/RAB1A/SLC25A4/PFKL/TNFSF11/ARL2/NPFF/PPARD/SLC9B2/FFAR1/TMF1/NDUFAF2/GATA3/PDX1/GIPR/SYBU/BAD	94
BP	GO:0031099	regeneration	60/4749	198/18670	0.06888	0.2644	0.2151	NOTCH1/CDK1/CDKN1A/NR4A3/PPARG/SULF2/DUSP10/AURKA/PTPRF/IL10/KLF4/CCNA2/GRN/CNTF/SPP1/PTCH1/CD9/TYMS/PTGFRN/GSN/NINJ1/RGMA/GPX1/WNT10B/TSPO/CCNB1/HMOX1/PKM/CPQ/CFLAR/NTRK3/AXL/FLT3/DHFR/EZH2/SCARF1/ULK1/VTN/BAK1/LRP1/ENO3/THY1/WNT7A/JUN/CEBPB/NINJ2/YAP1/ADAM15/CTNNA1/ADM/PTPRS/FZD9/MTR/NEFL/PPARD/TGFB1/RTN4R/CCND1/PDX1/LPIN1	60
BP	GO:0032088	negative regulation of NF-kappaB transcription factor activity	29/4749	88/18670	0.06949	0.2662	0.2166	NLRP3/IL10/KLF4/PTGIS/CD200/FOXP3/DAP/TRAIP/ARRB1/HAVCR2/SETD6/IRAK3/LRRC14/CYLD/CDKN2A/IRAK1/CHP1/ANXA4/NFKBIA/NFKBIL1/NLRC3/ZC3H12A/PIAS4/CARD8/COMMD6/ZNF675/PSMD10/COMMD7/SIRT1	29
BP	GO:0034103	regulation of tissue remodeling	29/4749	88/18670	0.06949	0.2662	0.2166	VDR/IL18/IL21/CSF1R/TFRC/GPNMB/CEACAM1/SPP1/BAX/SRC/PPARGC1B/CST3/S1PR1/PRKCA/PLEKHM1/CA2/FLT4/BGLAP/SFRP1/TNFRSF11B/SUCO/BCR/TMEM119/TNFSF11/THBS4/TGFB1/TMEM64/P2RX7/IL23A	29
BP	GO:0070098	chemokine-mediated signaling pathway	29/4749	88/18670	0.06949	0.2662	0.2166	CXCL13/WNK1/CCL20/CCL3L3/CXCR6/CCL22/CCR1/CCRL2/CXCL10/CCR6/CCR2/CCR4/CCL3/CCR5/CCL2/GPR35/CCL17/CCL18/CXCL9/CXCL2/CXCL3/CCR8/PADI2/CCL23/CCL7/PPBP/CCL15/CXCR5/CX3CR1	29
BP	GO:0035303	regulation of dephosphorylation	63/4749	209/18670	0.06977	0.2666	0.2169	PKMYT1/ITGA2/WNK1/LMTK3/PPP1R14A/LGALS3/YWHAE/MTMR3/PPP2R1A/PPP1R14B/TNF/SPPL3/SMG5/MTOR/BAG4/SWAP70/RIPK3/SRC/CDCA2/PPARGC1B/B3GAT3/PTBP1/SH2D4A/CD33/URI1/BOD1/IGFBP3/HTT/PPP2R3C/PHACTR2/PINK1/MTMR9/PTPRC/ITGA1/TIPRL/SFI1/LILRB2/FKBP1A/GBA/GNAI2/STYXL1/PPP1R16B/CHP1/CAMTA1/CEP192/MGAT5/PPP1R8/PPP1R26/TSKS/SMG6/ELL/SEMA4D/PPP2R3B/PPP1R15A/PPP1R9B/SLC39A10/TGFB1/CNST/PPP1R12A/PPP1R2/CDH5/PPP6R1/PPP1R3B	63
BP	GO:0035773	insulin secretion involved in cellular response to glucose stimulus	22/4749	64/18670	0.06982	0.2666	0.2169	RAC1/PIM3/TIAM1/ARRB1/ENY2/C2CD2L/SRI/TRPM4/NADK/OXCT1/LRP1/PRKCE/SIDT2/LRP5L/BRSK2/GHRL/RAB11FIP5/SLC9B2/NDUFAF2/PDX1/SYBU/BAD	22
BP	GO:0045600	positive regulation of fat cell differentiation	22/4749	64/18670	0.06982	0.2666	0.2169	PPARG/ZNF385A/SYAP1/ZFP36/ZBTB7C/ASXL2/HTR2A/PRDM16/CARM1/STK3/TRPM4/SH3PXD2B/CEBPB/ZC3H12A/TPH1/CREBL2/RARRES2/SFRP1/ZFP36L1/PPARD/METRNL/TMEM64	22
BP	GO:0046834	lipid phosphorylation	22/4749	64/18670	0.06982	0.2666	0.2169	TTC7A/DGKD/SOCS2/TTC7B/SOCS3/DGKZ/TMEM150A/PIKFYVE/IMPA2/PIP5K1B/PI4K2A/SLA2/INPP1/FAM126B/PIK3C3/IP6K1/SPHK2/PIP4K2A/IP6K2/AGK/PIP4K2B/PIP5K1A	22
BP	GO:2000378	negative regulation of reactive oxygen species metabolic process	22/4749	64/18670	0.06982	0.2666	0.2169	IL10/ACP5/PTGIS/SIRPA/HK2/CTNS/ABCD1/STAT3/TSPO/ABCD2/CFLAR/PINK1/ATP2B4/SIRT3/VDAC1/PARK7/ZC3H12A/SIRT2/CD34/BCR/KHSRP/FYN	22
BP	GO:0097711	ciliary basal body-plasma membrane docking	31/4749	95/18670	0.06994	0.2666	0.2169	CDK1/KIF24/NEK2/YWHAE/PLK4/PPP2R1A/ODF2/PLK1/CENPJ/TUBB/B9D2/FGFR1OP/TUBB4B/CEP152/CEP70/SFI1/TCTN1/TUBB4A/MARK4/CEP192/ALMS1/HAUS5/ACTR1A/TUBG1/TMEM67/CETN2/CEP72/CEP89/CEP97/CKAP5/NINL	31
BP	GO:0110020	regulation of actomyosin structure organization	31/4749	95/18670	0.06994	0.2666	0.2169	SDC4/RAC1/NF2/FHOD1/MTOR/BAG4/ARHGEF5/PTGER4/TGFB3/PAK1/PFN2/S1PR1/STMN1/CLASP2/CD47/LIMCH1/S100A10/MKKS/ARAP1/LIMK1/SH3PXD2B/ECT2/ALMS1/SFRP1/BMP10/TPM1/AKAP13/SORBS3/WASF2/CDC42/WAS	31
BP	GO:0048545	response to steroid hormone	111/4749	385/18670	0.06997	0.2666	0.2169	VDR/NR4A1/NOTCH1/TXNIP/CDKN1A/NR4A3/PPARG/ICAM1/NR3C2/CASP9/FOSL1/IL10/KANK2/PMEPA1/IL1RN/CBFB/GLB1/YWHAH/DNAJA1/CYP7B1/TGFB1I1/SPP1/TP63/FOSB/THRA/TYMS/EIF4EBP1/TNF/ZFP36/CYBB/ADTRP/ESRRA/NR3C1/PAQR7/TSPO/SRC/PPARGC1B/CFLAR/PAM/TRIP4/NTRK3/CRY1/TGFB3/PAK1/URI1/FLT3/FOXO1/ZFP36L2/RORC/SDC1/CARM1/CDK7/SMARCA4/PIAS1/DDIT4/AIF1/KLF9/TLR2/GBA/ARG1/RXRA/CREBRF/ARID1A/PARK7/PPP5C/UBE3A/NCOA4/DDX17/CA2/DDX54/PTGER2/PIAS2/IL22/ARNTL/CYBA/YAP1/PADI2/BGLAP/SFRP1/ADM/HSD3B2/ALDH3A1/ADIPOQ/TAF7/ESR1/AANAT/ZFP36L1/DEFA1B/SOX30/AKAP13/NEFL/ABCA3/LBH/FOS/PPARD/CATSPER2/TGFB1/STRN3/NR2C1/RARA/CCND1/ADAM9/CLDN4/PTAFR/PDX1/NCOR1/TFPI/BAD/MGARP/SIRT1/DUSP1	111
BP	GO:1901653	cellular response to peptide	111/4749	385/18670	0.06997	0.2666	0.2169	NR4A1/IL1B/RAB31/NR4A3/PPARG/ICAM1/KLF2/SH2B2/KLF4/CCNA2/CYFIP1/ATP6V0D1/MZB1/CDK5/CEACAM1/CDC6/SOCS2/EIF4EBP1/SYAP1/SLC2A8/KLF3/TLR4/PTPN1/ATP6V0B/ESRRA/STAT3/ADCY4/SORL1/MYO5A/SRC/SOCS3/ARHGEF2/PKM/CFLAR/CAMK2A/RAB13/ATP6V1E1/IGF1R/PAK1/ENHO/ADCY6/FFAR3/SLC2A4/MBD5/ATP6V0C/FOXO1/PHIP/CASR/RPL23/NAMPT/ANXA5/PRKCI/ATP6V1A/TIMELESS/NOD2/SP1/LRP1/ADIPOR1/SLA2/ARG1/GNAI2/TLR6/INSRR/FPR2/TSHR/CA2/CRK/ADCY3/CYBA/VIM/KLF10/APRT/GSK3A/RARRES2/ATP6V1G1/DDX11/BGLAP/GHRL/CDC5L/ADIPOQ/GPR21/PRNP/RIPK2/POR/FER/STAT5A/ZFP36L1/GCLC/CPEB1/PRKCB/PRKACB/INSR/MAX/ADCY9/APC/HDAC9/STAT1/ATP6V1E2/CYP11A1/NUCKS1/ID1/TGFB1/JAK3/SHC1/GKAP1/LPIN1/FYN/TRIB3/MGARP/USO1/SIRT1	111
BP	GO:2000379	positive regulation of reactive oxygen species metabolic process	33/4749	102/18670	0.07011	0.267	0.2172	IL1B/CDKN1A/ICAM1/KLF2/KLF4/CLEC7A/TNF/TLR4/DDAH2/GADD45A/MTOR/TSPO/RIPK3/CLU/CD177/PKD2/ROMO1/AIF1/GNAI2/RAB27A/TLR6/FPR2/PARK7/ZNF205/CYBA/ZC3H12A/TYROBP/HBB/NNT/INSR/TGFB1/KLRK1/PDGFB	33
BP	GO:0072659	protein localization to plasma membrane	77/4749	260/18670	0.07025	0.2674	0.2175	TTC7A/RAB31/SQSTM1/ITGA3/TSPAN5/CDK5/ANXA2P2/BBS2/LGALS3/GORASP1/PTCH1/TNF/AKAP5/ANK1/TTC7B/ANXA2/MYADM/DCHS1/ZFYVE27/RANGRF/BAG4/MYO5A/GRIPAP1/SEC16A/RHOG/CLIP3/PLS1/RAB13/GGA2/RAB3D/TMEM150A/PTPN9/ATP1B1/SMURF1/SPTBN1/FGF13/EZR/MPP5/CLASP2/LRRC15/RILPL2/PRKCI/STAC3/FLOT1/SCRIB/S100A10/LRP1/STAC/ATP1B3/PRKCE/VAMP3/BCL2L1/BSG/RAPGEF2/FAM126B/PIGW/VTI1B/ADIPOQ/PRNP/LDLRAP1/GOPC/TESC/LRP6/PACSIN1/P2RY1/RAB15/ARF6/RAB34/ANKRD9/CACNB2/EHD3/PIP5K1A/TGFB1/CNST/LAMA5/SLMAP/ACTB	77
BP	GO:0097696	STAT cascade	51/4749	166/18670	0.07128	0.2703	0.2199	LIF/NOTCH1/IL18/CSF2/IL21/CSF1R/IL10/DOT1L/BCL3/TNFRSF18/CNTF/NF2/PPP2R1A/SOCS2/STAMBP/TNF/PTPN1/STAT3/PARP14/CCR2/SOCS3/PKD2/FLT3/CCL2/PTK6/PTPRC/PIAS1/PPP2CA/ADIPOR1/IL26/OSM/HGS/STAT4/GGNBP2/PIBF1/IL7R/MGAT5/CNOT7/IL13/IL20/IL4/ARL2BP/F2R/CRLF3/FER/STAT5A/STAT1/IL10RA/JAK3/FYN/IL23A	51
BP	GO:0032210	regulation of telomere maintenance via telomerase	19/4749	54/18670	0.07134	0.2703	0.2199	AURKB/NEK2/SMG5/SRC/PIF1/CCT5/TERF1/TNKS2/ACD/CTC1/POT1/SMG6/ATR/TINF2/ATM/MAPK1/FBXO4/TERF2/CCT3	19
BP	GO:0035825	homologous recombination	19/4749	54/18670	0.07134	0.2703	0.2199	TOP2A/TRIP13/RAD54L/SYCE3/UBE2B/RAD51/DMC1/MND1/HELQ/REC8/EME1/KLHDC3/UBR2/ANKRD31/ATM/MLH3/RNF212/HDAC10/RAD54B	19
BP	GO:0014002	astrocyte development	16/4749	44/18670	0.07136	0.2703	0.2199	IL1B/ADORA2A/TTBK1/GRN/CNTF/TNF/TLR4/LDLR/DRD1/LRP1/FPR2/VIM/IFNGR1/S100A8/C1QA/DLL1	16
BP	GO:0042269	regulation of natural killer cell mediated cytotoxicity	16/4749	44/18670	0.07136	0.2703	0.2199	IL21/CEACAM1/LGALS9/ULBP2/RAET1E/HLA-G/SH2D1A/HAVCR2/HLA-E/MICA/LAG3/CADM1/CRK/LAMP1/ULBP1/KLRK1	16
BP	GO:0090382	phagosome maturation	16/4749	44/18670	0.07136	0.2703	0.2199	MYO7A/RAB31/ATP6V0D1/ATP6V0B/RAB32/ATP6V1E1/ATP6V0C/CORO1A/ATP6V1A/TMEM175/SYT11/RAB38/ATP6V1G1/RAB34/ATP6V1E2/P2RX7	16
BP	GO:1904407	positive regulation of nitric oxide metabolic process	16/4749	44/18670	0.07136	0.2703	0.2199	IL1B/ICAM1/KLF2/KLF4/CLEC7A/TNF/TLR4/DDAH2/MTOR/CLU/PKD2/AIF1/TLR6/HBB/INSR/KLRK1	16
BP	GO:0043409	negative regulation of MAPK cascade	56/4749	184/18670	0.07145	0.2703	0.2199	LIF/IL1B/PBK/FOXM1/DUSP10/DUSP4/KLF4/PTPN6/DUSP6/SPRED2/SIRPA/DNAJA1/ATF3/NF2/PPP2R1A/TLR4/CHRNA10/BTN2A2/PTPN1/PDCD4/SORL1/DUSP5/ARRB1/IGF1R/FKTN/IRAK3/FOXO1/SYNJ2BP/DUSP16/PINK1/PTPRC/EZR/CYLD/PPP2CA/PRDM15/GBA/NDRG2/SIRT3/TAOK3/RAPGEF1/DEFB114/C3orf33/DUSP18/SFRP1/ADIPOQ/AIDA/TIMP3/STK38/DUSP14/ZNF675/PSMD10/UCHL1/NUP62/P2RX7/NCOR1/DUSP1	56
BP	GO:0048639	positive regulation of developmental growth	56/4749	184/18670	0.07145	0.2703	0.2199	VEGFA/NOTCH1/CDK1/SRF/CYFIP1/BBS2/TNFRSF12A/CSF1/SEMA7A/MTOR/ZFYVE27/PIM1/CCNB1/PARP2/SYT4/PLS1/NTRK3/PAK1/CPNE5/FGF9/RBPJ/HLX/SMURF1/EZR/TWF2/L1CAM/MKKS/LRP1/LIMK1/CACNA2D2/BASP1/SH3PXD2B/IST1/YAP1/IL7/RASAL1/GHRL/GPR21/SERP1/ACACB/SEMA4D/INSR/BMP10/FGF8/DLL1/PPARD/RAG2/PLCB1/RUFY3/SEMA5A/ADNP/MAPK1/TRPC5/MIR17HG/GDI1/ILK	56
BP	GO:2000045	regulation of G1/S transition of mitotic cell cycle	56/4749	184/18670	0.07145	0.2703	0.2199	KIF14/GTSE1/E2F7/E2F8/CDK1/CDKN1A/AURKA/KANK2/CDKN2B/KLF4/PTPN6/ZNF385A/GPNMB/CDC6/PML/E2F1/PLK2/BAX/BTN2A2/CDC25C/CDKN2C/GADD45A/CCNB1/SFN/RPL26/CDC45/CDK2/RFWD3/CDK2AP2/PKD2/CCL2/FBXO31/BID/CARM1/AIF1/CNOT3/EZH2/CDK10/TFDP2/MUC1/CDKN2A/MDM4/RBL2/PSME2/CNOT7/TMEM14B/GIGYF2/GML/CHEK2/ADAMTS1/ATM/ANKRD17/PLCB1/CUL4A/ZNF655/CCND1	56
BP	GO:1904427	positive regulation of calcium ion transmembrane transport	24/4749	71/18670	0.0717	0.2709	0.2204	HSPA2/BAX/CXCL10/TRPC1/ATP2A1/KCNE3/SRI/PKD2/HTT/ATP1B1/GSTO1/STAC3/CXCL9/DRD1/STAC/THY1/CD19/SUMO1/NTSR1/LACRT/IL13/F2R/CACNB2/EHD3	24
BP	GO:0007204	positive regulation of cytosolic calcium ion concentration	93/4749	319/18670	0.07189	0.2709	0.2204	CXCL13/GNA15/FPR1/CXCR6/PTPN6/NMB/FPR3/CCR1/CDK5/CCRL2/CHERP/PML/HMGB1/JSRP1/CHRNA10/NOL3/BAX/CXCL10/SPPL3/TRPC1/SWAP70/CCR6/CCR2/MYO5A/HCRT/CCR4/TGM2/F2RL2/PDE4D/HTR2A/CCL3/PTGER4/SRI/CYSLTR1/PKD2/RIC3/CCR5/HTT/S1PR1/GPR33/GPR35/GSTO1/TPCN1/PTPRC/BCAP31/CORO1A/TRPM4/RASA3/CXCL9/P2RY10/BAK1/DRD1/FKBP1A/ATP2B4/LRP1/DDIT3/THY1/CD19/BDKRB2/CNR1/NTSR1/FPR2/C3AR1/PRKCE/PTGER2/CCR8/CYBA/LACRT/GPR32/TBXA2R/PTGER1/IL13/ADM/GHRL/CAMK2D/P2RX5/PRNP/ESR1/F2R/LRP6/P2RY1/CACNB2/NPFF/PLCB1/TGFB1/GALR2/TRPC5/CXCR5/P2RX7/CX3CR1/GIPR/FYN/DLG4	93
BP	GO:0002082	regulation of oxidative phosphorylation	12/4749	31/18670	0.07202	0.2709	0.2204	PPIF/CDK1/SLC25A23/ABCD1/DNAJC30/CCNB1/VCP/PINK1/PARK7/AK4/ISCU/NUPR1	12
BP	GO:0006691	leukotriene metabolic process	12/4749	31/18670	0.07202	0.2709	0.2204	ABCC1/ALOX5AP/GGT1/TLR2/ALOX5/GGTLC2/CYP4F12/MAPKAPK2/MGST2/GGT7/MGST3/PLA2G5	12
BP	GO:0009394	2'-deoxyribonucleotide metabolic process	12/4749	31/18670	0.07202	0.2709	0.2204	DCTPP1/TYMS/CMPK2/DTYMK/NUDT16/NUDT1/AK5/DCTD/SAMHD1/GUK1/NEIL1/OGG1	12
BP	GO:0010165	response to X-ray	12/4749	31/18670	0.07202	0.2709	0.2204	CDKN1A/BRCA2/TP53BP1/XRCC6/ERCC8/BRCC3/SFRP1/ATM/NUCKS1/CCND1/GATA3/ERCC1	12
BP	GO:0010762	regulation of fibroblast migration	12/4749	31/18670	0.07202	0.2709	0.2204	SDC4/RFFL/CORO1C/BAG4/PAK1/C5orf30/PAK3/WDPCP/ARHGAP4/PRKCE/FER/TGFB1	12
BP	GO:0046471	phosphatidylglycerol metabolic process	12/4749	31/18670	0.07202	0.2709	0.2204	THEM5/PLA2G12A/LPCAT4/PTPMT1/PLA2G2A/TAMM41/LCLAT1/PLA2G5/TAZ/HADHB/CRLS1/PGS1	12
BP	GO:0071539	protein localization to centrosome	12/4749	31/18670	0.07202	0.2709	0.2204	STIL/AURKA/SPAG5/MARK4/PIBF1/CEP192/NSFL1C/CEP72/APC/PARD6A/MCPH1/NUP62	12
BP	GO:1903393	positive regulation of adherens junction organization	12/4749	31/18670	0.07202	0.2709	0.2204	VEGFA/SDC4/RAC1/MAPRE2/LIMS1/S100A10/IQSEC1/THY1/EPB41L5/SFRP1/ARF6/FMN1	12
BP	GO:1903313	positive regulation of mRNA metabolic process	26/4749	78/18670	0.07299	0.2744	0.2232	ZFP36/ZC3H12D/NUP98/PLEKHN1/CCNB1/TNRC6B/CIRBP/UPF1/ZFP36L2/MEX3D/RBM23/SF3B4/ZC3H12A/PRPF19/CNOT7/YTHDF3/RBMY1B/PRDX6/METTL16/GIGYF2/ZC3HAV1/ZFP36L1/CPEB1/RBM3/NCBP2/KHSRP	26
BP	GO:0050679	positive regulation of epithelial cell proliferation	62/4749	206/18670	0.0734	0.2758	0.2244	EGR3/IQGAP3/NR4A1/TWIST1/VEGFA/NOTCH1/NR4A3/IL10/LRG1/GRN/CYP7B1/TP63/HMGB1/SIRT6/AKT3/MTOR/MMP12/STAT3/HMOX1/CFLAR/FGF9/PDCL3/TCF7L2/ZNF304/KDM5B/PRKCA/TGM1/NOD2/SP1/ARG1/WNT7A/PPP1R16B/JUN/ERBB2/TNFSF12/SOX11/CYBA/NRARP/ZNF703/LACRT/FLT4/EGFL7/EMC10/SFRP1/GHRL/F3/DLX5/STAT5A/HTRA1/THBS4/WDR48/ID1/TGFB1/SEMA5A/HAS2/CCND1/PDGFB/ESRP2/VEGFC/BAD/NME2/SIRT1	62
BP	GO:0002223	stimulatory C-type lectin receptor signaling pathway	36/4749	113/18670	0.07398	0.2777	0.2259	RELB/CLEC10A/CARD9/SRC/PSMD8/PSMD1/PSMD2/PAK1/PSMF1/PAK3/MUC1/PSMD9/PSMA5/CLEC4D/PSMB7/ICAM2/FBXW11/TAB1/PSMD5/PSME2/BTRC/CARD11/PSMB5/PRKACB/PSMB4/TRAF6/PSMA3/PSMD10/PSMB1/PSMD7/PSMB3/KLRK1/PSMC5/FYN/PAK2/PSMD11	36
BP	GO:0006879	cellular iron ion homeostasis	21/4749	61/18670	0.07421	0.2777	0.2259	TTC7A/ATP6V0D1/TFRC/TMPRSS6/FXN/HMOX1/ATP13A2/SRI/HEPH/NUBP1/ATP6V1A/FTL/ACO1/NCOA4/FTH1/ATP6V1G1/ISCU/HMOX2/CYBRD1/CCDC115/SLC40A1	21
BP	GO:0032233	positive regulation of actin filament bundle assembly	21/4749	61/18670	0.07421	0.2777	0.2259	SDC4/RAC1/NF2/FHOD1/MTOR/BAG4/SWAP70/ARHGEF5/TGFB3/PAK1/PFN2/CD47/LIMCH1/S100A10/LIMK1/SH3PXD2B/SFRP1/TPM1/SORBS3/ID1/CDC42	21
BP	GO:0034113	heterotypic cell-cell adhesion	21/4749	61/18670	0.07421	0.2777	0.2259	IL1B/WNK1/IL10/KLF4/IL1RN/PERP/SIRPA/DSC2/TNF/CD200/MYADM/ITGAX/CD1D/PTPRC/CD47/FLOT1/CD58/LILRB2/THY1/CD44/ADIPOQ	21
BP	GO:0045123	cellular extravasation	21/4749	61/18670	0.07421	0.2777	0.2259	ICAM1/IL1R1/SIRPA/TNF/RIPK3/CCR2/PTGER4/CD177/CCL2/ITGA1/CD47/IL27RA/THY1/CRK/CD99L2/FER/BCR/PLCB1/PTAFR/ADD2/CX3CR1	21
BP	GO:0050701	interleukin-1 secretion	21/4749	61/18670	0.07421	0.2777	0.2259	NLRP3/TLR8/HK1/LGALS9/PML/HMGB1/TLR4/S100A13/LILRA2/IL1R2/CCL3/ABCA1/NOD2/TLR6/ZC3H12A/LILRA5/RIPK2/CARD8/FZD5/TRIM16/P2RX7	21
BP	GO:1903902	positive regulation of viral life cycle	21/4749	61/18670	0.07421	0.2777	0.2259	NOTCH1/TOP2A/IFIT1/ANXA2P2/LGALS9/SMC3/CHMP2B/KPNA2/ANXA2/PPIH/CD74/LGALS1/TBC1D20/FMR1/RAD23A/CNOT7/CHMP2A/STAU1/STOM/NUCKS1/CHMP3	21
BP	GO:1904894	positive regulation of STAT cascade	30/4749	92/18670	0.07426	0.2777	0.2259	LIF/NOTCH1/IL18/CSF2/IL21/CSF1R/IL10/TNFRSF18/CNTF/TNF/STAT3/PARP14/SOCS3/FLT3/PTK6/ADIPOR1/IL26/OSM/PIBF1/IL7R/MGAT5/IL13/IL20/IL4/ARL2BP/F2R/CRLF3/IL10RA/FYN/IL23A	30
BP	GO:0035966	response to topologically incorrect protein	60/4749	199/18670	0.07487	0.2798	0.2277	HSPA2/CHAC1/ATP6V0D1/DNAJA1/ATF3/HSPA5/CREB3L2/SDF2L1/SERP2/HSPA1A/DERL1/BAX/TPP1/DNAJB5/PTPN1/ZBTB17/LMNA/SYVN1/POMT2/HSPA9/VCP/DNAJB12/CLU/HERPUD1/ATF4/ASNS/CTH/CCL2/EXTL2/PARP16/BAK1/DDIT3/CREBRF/JKAMP/SDF2/EDEM2/BAG3/FICD/GSK3A/HSPA6/KLHDC3/YIF1A/DDX11/EIF2AK3/ERN1/SERP1/CANX/HSPA1L/RNF121/HSPA14/MBTPS2/PPP1R15A/DNAJB4/THBS4/HERPUD2/TMEM33/DNAJB2/CCND1/SHC1/UBE2W	60
BP	GO:0002691	regulation of cellular extravasation	11/4749	28/18670	0.07542	0.2812	0.2288	ICAM1/IL1R1/RIPK3/CCR2/PTGER4/IL27RA/THY1/CD99L2/BCR/PLCB1/PTAFR	11
BP	GO:0048679	regulation of axon regeneration	11/4749	28/18670	0.07542	0.2812	0.2288	PTPRF/KLF4/GRN/CNTF/SPP1/RGMA/NTRK3/SCARF1/LRP1/PTPRS/RTN4R	11
BP	GO:0090344	negative regulation of cell aging	11/4749	28/18670	0.07542	0.2812	0.2288	TWIST1/FOXM1/BCL6/PLK2/AKT3/FBXO5/NAMPT/BCL2L12/MAP3K3/TERF2/SIRT1	11
BP	GO:2000108	positive regulation of leukocyte apoptotic process	11/4749	28/18670	0.07542	0.2812	0.2288	NR4A3/IL10/PDCD1/PRELID1/LGALS9/BAX/CDKN2A/IDO1/RAPGEF2/P2RX7/SIRT1	11
BP	GO:0044743	protein transmembrane import into intracellular organelle	15/4749	41/18670	0.07556	0.2814	0.2289	TIMM17A/TIMM10/TIMM22/TIMM50/ROMO1/GRPEL1/PEX2/PEX5/PAM16/AGK/CHCHD4/PEX13/NDUFA13/TIMM9/PEX1	15
BP	GO:0001558	regulation of cell growth	119/4749	416/18670	0.07561	0.2814	0.2289	RASGRP2/HBEGF/GNG4/KIF14/VEGFA/CDKN1A/PPARG/SRF/BCL11A/IGFBP4/BCL6/CYFIP1/CDK5/ENO1/CEACAM1/SPP1/PPP2R1A/PML/SOCS2/SEMA4C/TNFRSF12A/SEMA7A/ING1/HSPA1A/CTTN/CDKN2C/BRAT1/MTOR/NAIF1/ZFYVE27/PSRC1/MSX1/SEMA3G/FXN/PARP2/FGFR1OP/SFN/TMC8/SYT4/SEMA6C/PAK4/SDCBP/BST2/NTRK3/PPT1/PAK1/URI1/BAP1/CPNE5/IGFBP3/SEMA6B/NUBP1/SMURF1/SMARCA4/FGF13/N6AMT1/ARHGAP4/TWF2/L1CAM/ADIPOR2/CXCL16/PPP2CA/TAF9B/CDKN2A/LRP1/ADIPOR1/LIMK1/TTL/EBAG9/CYP27B1/SH3BP4/ATAD3A/ERBB2/EXOSC2/ZNF639/SEMA3B/IST1/CYBA/ADAM15/DDR1/SEMA5B/GSK3A/RASAL1/CDKN2AIP/SFRP1/SGK2/S100A8/CAMK2D/CRLF3/PTPRS/DCBLD2/MAD2L2/SEMA4D/LAMTOR2/BMP10/KLHL22/CLSTN3/SPHK2/EAF2/IP6K2/PPP1R9B/PPARD/PSMD10/RUFY3/TGFB1/SEMA5A/CDC42/NET1/NDUFA13/RTN4R/ADNP/DNAJB2/TRPC5/SESN2/GDI1/EXOSC9/OSGIN2/ILK/SIRT1	119
BP	GO:0009612	response to mechanical stimulus	63/4749	210/18670	0.07565	0.2814	0.2289	IL1B/TXNIP/PPARG/ITGA2/FOSL1/NTRK1/RAC1/TLR8/PPL/PTCH1/FOSB/TNFRSF8/TLR4/CHRNA10/USP53/CXCL10/GADD45A/TMEM150C/CCNB1/SRC/MBD2/HTR2A/MAP3K2/PTGER4/KCNJ2/PKD2/ASNS/HTT/FAS/TNFRSF10B/TIFAB/COL11A1/ERCC8/MKKS/BAK1/CASP8AP2/JUN/SLC38A2/CHEK1/NFKBIA/PIEZO1/STRC/MPO/CYBA/PSPH/BAG3/MAP2K4/IL13/BGLAP/GCLC/CNN2/P2RY1/STAT1/TMC2/XPA/FOS/TGFB1/TCAP/KCNK2/LRP11/P2RX7/BAD/FYN	63
BP	GO:0043523	regulation of neuron apoptotic process	63/4749	210/18670	0.07565	0.2814	0.2289	KIF14/TYRO3/NR4A3/CASP9/ADORA2A/NTRK2/FAIM2/NTRK1/GRN/CNTF/VSTM2L/MYBL2/MCL1/CDK5/STAMBP/ASCL1/TNF/FOXB1/BAX/HMOX1/ARRB1/CCL3/AXL/TGFB3/PPT1/ATF4/AMBRA1/CCL2/NQO1/PAK3/PINK1/CORO1A/ITGA1/PRKCI/MAP3K11/LRP1/DDIT3/PARK7/JUN/TFAP2B/AGAP2/CTSZ/CEBPB/BCL2L1/MAP2K4/PRNP/F2R/NAE1/TYROBP/FZD9/GCLC/NUPR1/FGF8/NEFL/NTF3/ATM/POU4F1/NMNAT1/ADNP/GATA3/CX3CR1/FYN/ILK	63
BP	GO:0007422	peripheral nervous system development	25/4749	75/18670	0.0776	0.2885	0.2347	EGR3/EGR2/CDK1/NTRK2/GPC1/CDK5/SKI/SLC5A3/FA2H/NAB2/NTRK3/MPP5/NDRG1/SOX8/NAB1/ERBB2/ADAM22/PMP22/POU3F1/SIRT2/DICER1/MED12/NTF3/POU4F1/ILK	25
BP	GO:1901568	fatty acid derivative metabolic process	51/4749	167/18670	0.07804	0.29	0.2359	IL1B/ABCC1/PTGIS/ALOX5AP/CYP2S1/ABHD16A/SLC25A1/CYP4F22/TECR/GPX1/ABCD1/THEM5/PON2/SCD/GGT1/FAR2/FABP5/CD74/PPT1/HMGCL/EPHX2/ACSL1/HSD17B8/OXCT1/TLR2/OXCT2/ALOX5/GGTLC2/ZADH2/GPX4/TBXAS1/ELOVL7/PIBF1/PTGES2/CYP2C18/ELOVL1/BDH2/ACSL4/CYP4F12/MAPKAPK2/DGAT2/MGST2/GGT7/FASN/CYP2D6/MGST3/HPGD/CYP2U1/PLA2G5/TYRP1/SIRT1	51
BP	GO:0001649	osteoblast differentiation	67/4749	225/18670	0.0784	0.2911	0.2369	TWIST1/NOTCH1/RASSF2/TP53INP2/CBFB/GPNMB/SPP1/TP63/PTCH1/TNF/SEMA7A/SKI/ESRRA/WNT10B/CLIC1/NBR1/SNAI1/FBXO5/CTHRC1/LIMD1/GNAS/RPS15/CCL3/WWTR1/PTHLH/FGF9/COL6A1/IGFBP3/FAM20C/SMAD6/RUNX2/PDLIM7/JAG1/ATRAID/TRPM4/MEF2D/FIGNL1/IFITM1/WWOX/SOX8/SH3PXD2B/ACVR2B/MYBBP1A/CEBPB/LRP5L/SOX11/RDH14/FBL/BGLAP/SMAD1/SFRP1/IFT80/RRBP1/SUCO/DLX5/CLEC5A/SEMA4D/FASN/BMP3/AXIN2/TMEM119/ID1/TMEM64/ASF1A/AMELX/RRAS2/ILK	67
BP	GO:0032642	regulation of chemokine production	27/4749	82/18670	0.07844	0.2911	0.2369	EGR1/TWIST1/IL1B/CSF1R/IL10/KLF4/SIRPA/TIRAP/CLEC7A/LGALS9/TNF/TLR4/IL4R/FFAR2/HMOX1/HAVCR2/CD74/FFAR3/SIGIRR/AIF1/TLR2/LRP1/C1QTNF3/IL7/ADIPOQ/RIPK2/ZFPM1	27
BP	GO:0009648	photoperiodism	10/4749	25/18670	0.07872	0.2913	0.237	PML/PPP1CB/CRY1/PER2/CRTC1/BHLHE40/RBM4B/AANAT/MTA1/PER3	10
BP	GO:0032104	regulation of response to extracellular stimulus	10/4749	25/18670	0.07872	0.2913	0.237	KANK2/BBS2/MTOR/NENF/CCK/MKKS/CYP27B1/NUCB2/GHRL/NPFF	10
BP	GO:0032107	regulation of response to nutrient levels	10/4749	25/18670	0.07872	0.2913	0.237	KANK2/BBS2/MTOR/NENF/CCK/MKKS/CYP27B1/NUCB2/GHRL/NPFF	10
BP	GO:0060330	regulation of response to interferon-gamma	10/4749	25/18670	0.07872	0.2913	0.237	PPARG/PARP14/SOCS3/PIAS1/TXK/ARG1/SUMO1/IFNGR1/STAT1/JAK1	10
BP	GO:0060334	regulation of interferon-gamma-mediated signaling pathway	10/4749	25/18670	0.07872	0.2913	0.237	PPARG/PARP14/SOCS3/PIAS1/TXK/ARG1/SUMO1/IFNGR1/STAT1/JAK1	10
BP	GO:0046467	membrane lipid biosynthetic process	44/4749	142/18670	0.07877	0.2913	0.237	B3GNT5/SGMS1/GBGT1/SPTSSA/SGMS2/KDSR/TNF/FA2H/P2RX1/PIGK/PIGH/SGPP1/DPM2/ST8SIA1/PRKD3/GAL3ST2/PIGQ/PIGO/GBA/ELOVL7/ACER1/ELOVL1/ACER2/PIGC/ASAH2/PIGW/B4GALT5/ALDH3B1/ASAH2B/ORMDL2/SPHK2/GAL3ST4/PIGM/PIGA/AGK/ST8SIA3/CERS3/CSNK1G2/ST6GALNAC6/PPM1L/P2RX7/PIGG/ORMDL3/PIGT	44
BP	GO:1905269	positive regulation of chromatin organization	33/4749	103/18670	0.07881	0.2913	0.237	LIF/IL1B/VEGFA/BCL6/PHF19/SIRT6/FOXP3/SMARCB1/LMNA/NAP1L2/CCNB1/ARRB1/MORC2/KAT2A/UBE2N/RNF40/ZNF304/PINK1/EED/BRD4/MUC1/FMR1/C6orf89/DMRTC2/TADA2A/SPHK2/CTBP1/ATM/TGFB1/PPHLN1/SETDB1/GATA3/SIRT1	33
BP	GO:0006949	syncytium formation	20/4749	58/18670	0.07891	0.2914	0.2371	CD109/ADAM12/CAMK1/CD9/PTGFRN/CXCL10/SBNO2/IL4R/CFLAR/MYOF/CXCL9/FLOT1/TANC1/MYH9/TYROBP/FER1L5/ADAM9/TCTA/ERCC1/GCM1	20
BP	GO:0030516	regulation of axon extension	31/4749	96/18670	0.07898	0.2914	0.2371	VEGFA/SRF/CYFIP1/CDK5/SEMA4C/TNFRSF12A/SEMA7A/CTTN/ZFYVE27/SEMA3G/SEMA6C/NTRK3/PAK1/SEMA6B/ARHGAP4/TWF2/L1CAM/LRP1/LIMK1/TTL/SEMA3B/SEMA5B/PTPRS/SEMA4D/RUFY3/SEMA5A/RTN4R/ADNP/TRPC5/GDI1/ILK	31
BP	GO:0048010	vascular endothelial growth factor receptor signaling pathway	31/4749	96/18670	0.07898	0.2914	0.2371	IL1B/MAPK11/VEGFA/RAC1/CYFIP1/NCF4/SH2D2A/CYBB/PTPN1/CYFIP2/SRC/DOCK1/AXL/MYOF/FGF9/VAV2/VTN/HGS/FLT1/CRK/CYBA/FLT4/MAPKAPK2/PRKCB/NCF1/WASF2/CDC42/SHC2/VEGFC/FYN/PAK2	31
BP	GO:0022406	membrane docking	54/4749	178/18670	0.07935	0.2925	0.2379	CDK1/ICAM1/KIF24/NEK2/YWHAE/PLK4/PPP2R1A/ODF2/PLK1/CENPJ/TUBB/STX11/B9D2/STX5/BLOC1S6/FGFR1OP/CAMK2A/VPS33B/TUBB4B/RAB3D/SNAP29/SCFD2/STX1B/CEP152/CEP70/EZR/SFI1/TCTN1/STX19/STX12/PPFIA3/CHP1/TUBB4A/MARK4/CEP192/VAMP3/STX16/EXOC6B/ALMS1/HAUS5/VTI1B/ACTR1A/STX2/TUBG1/TMEM67/CETN2/CEP72/RAB15/RALB/CEP89/CEP97/CKAP5/NINL/USO1	54
BP	GO:0090090	negative regulation of canonical Wnt signaling pathway	54/4749	178/18670	0.07935	0.2925	0.2379	EGR1/NOTCH1/IGFBP4/TLE4/TLE2/NKD1/CTHRC1/LIMD1/PSMD8/DVL3/SFRP4/TMEM170B/PSMD1/PSMD2/FZD6/WWTR1/PSMF1/PFDN5/FOXO1/LRP4/TCF7L2/CYLD/STK3/TLE3/DVL1/PSMD9/PSMA5/DDIT3/RAPGEF1/EMD/PSMB7/INVS/PSMD5/SIAH2/GSK3A/PSME2/SFRP1/PSMB5/MLLT3/BICC1/MAD2L2/LRP6/PSMB4/PSMA3/APC/AXIN2/PSMD10/TMEM64/PSMB1/PSMD7/PSMB3/PSMC5/IGFBP6/PSMD11	54
BP	GO:0030073	insulin secretion	62/4749	207/18670	0.07955	0.293	0.2384	IL1B/RAC1/IL1RN/PIM3/SLC16A1/TNF/BLK/MYO5A/TIAM1/ABAT/ARRB1/ENY2/C2CD2L/SRI/ENHO/PER2/CASR/TCF7L2/PRKCA/TRPM4/NADK/OXCT1/PFKFB2/PSMD9/LRP1/CACNA2D2/SIRT3/CNR1/PARK7/TFAP2B/ACVR1C/SLC25A5/ACVR2B/SNX19/CAMK2G/PRKCE/SIDT2/LRP5L/ARNTL/GLUD1/BRSK2/SFRP1/GHRL/KCNG2/CPT1A/ARL2BP/RAB11FIP5/SERP1/DOC2B/FAM3B/SLC25A4/PFKL/ARL2/NPFF/PPARD/SLC9B2/FFAR1/NDUFAF2/PDX1/GIPR/SYBU/BAD	62
BP	GO:0015804	neutral amino acid transport	14/4749	38/18670	0.07999	0.2941	0.2393	SLC1A5/SLC1A1/SLC7A5/SFXN1/NFKBIE/SLC36A1/CTNS/SLC43A1/SLC1A4/SLC3A2/SLC38A9/SLC38A2/SLC36A4/SLC6A20	14
BP	GO:0032620	interleukin-17 production	14/4749	38/18670	0.07999	0.2941	0.2393	IL18/IL21/TNFSF4/TLR4/FOXP3/LY9/RFTN1/NOD2/IL27RA/OSM/MR1/PRNP/TGFB1/IL23A	14
BP	GO:0097064	ncRNA export from nucleus	14/4749	38/18670	0.07999	0.2941	0.2393	SEC13/NUP98/NUP153/NUP88/POM121C/NUP205/RAE1/NUP50/NUP93/NUP35/AAAS/NCBP2/NUP62/SEH1L	14
BP	GO:0006874	cellular calcium ion homeostasis	130/4749	458/18670	0.08008	0.2943	0.2394	VDR/CXCL13/GNA15/FPR1/CXCR6/PTPN6/NMB/FPR3/CCR1/CDK5/ANXA2P2/CCRL2/YWHAE/CHERP/PML/KCTD17/HMGB1/CDH23/JSRP1/CHRNA10/NCS1/NOL3/BAX/CXCL10/SPPL3/TRPC1/SLC25A23/ANXA2/SWAP70/CCR6/ATP13A1/CCR2/MYO5A/HCRT/CCR4/P2RX1/TGM2/ATP13A4/F2RL2/PDE4D/HTR2A/ATP2A1/CCL3/ATP13A2/PTGER4/SRI/MICU1/CYSLTR1/HERPUD1/PKD2/ATF4/RIC3/EPHX2/CCR5/HTT/S1PR1/GPR33/GPR35/ATP1B1/CASR/GSTO1/TPCN1/PTPRC/BCAP31/CORO1A/TRPM4/RASA3/ANXA5/CXCL9/P2RY10/BAK1/DRD1/FKBP1A/ATP2B4/LRP1/DDIT3/THY1/CD19/BDKRB2/CNR1/NTSR1/SLC24A3/FPR2/C3AR1/GPR12/PRKCE/PTGER2/CCR8/CYBA/TMEM203/LACRT/GPR32/TBXA2R/PTGER1/IL13/CALB2/ADM/GHRL/CAMK2D/P2RX5/PRNP/ESR1/F2R/FZD9/LRP6/PRKCB/P2RY1/TRPC7/CCL23/HEXB/CACNB2/CCL7/NPFF/PLCB1/TGFB1/TMEM64/CCL15/GALR2/SV2A/TRPC5/CDH5/CXCR5/P2RX7/CX3CR1/PDE6B/GIPR/SLC35G1/FYN/DLG4/GTF2I	130
BP	GO:0002279	mast cell activation involved in immune response	17/4749	48/18670	0.08049	0.2951	0.2401	NR4A3/FES/LGALS9/S100A13/GAB2/MILR1/IL4R/HMOX1/BTK/LAT/SNAP23/UNC13D/RAC2/RABGEF1/IL13/FER/SPHK2	17
BP	GO:0002762	negative regulation of myeloid leukocyte differentiation	17/4749	48/18670	0.08049	0.2951	0.2401	TRIB1/CEACAM1/TLR4/PIAS3/ZBTB46/LILRB4/CCL3/TOB2/SFRP1/ADIPOQ/IL4/ZNF675/CUL4A/RARA/ZFPM1/TCTA/NME2	17
BP	GO:0046850	regulation of bone remodeling	17/4749	48/18670	0.08049	0.2951	0.2401	CSF1R/TFRC/SPP1/SRC/PPARGC1B/S1PR1/PRKCA/PLEKHM1/CA2/BGLAP/SFRP1/TNFRSF11B/SUCO/TMEM119/TNFSF11/TMEM64/P2RX7	17
BP	GO:1903727	positive regulation of phospholipid metabolic process	17/4749	48/18670	0.08049	0.2951	0.2401	SRC/DGKZ/HTR2A/AMBRA1/FLT3/VAV2/NOD2/CD19/FLT1/FPR2/AGAP2/RAB38/PIK3R4/TNFAIP8L3/TAZ/TGFB1/PDGFB	17
BP	GO:0042133	neurotransmitter metabolic process	47/4749	153/18670	0.08073	0.2954	0.2403	IL1B/ICAM1/KLF2/IL10/ACP5/KLF4/RAC1/PTGIS/SIRPA/CLEC7A/TNF/TLR4/DDAH2/MTOR/SDS/TSPO/ABAT/MOXD1/GLDC/CLU/SARDH/PKD2/NQO1/GCAT/CD47/AIF1/TLR2/BHMT/GCHFR/ATP2B4/TLR6/DPYD/ZC3H12A/TPH1/CD34/POR/HBB/INSR/ALDH7A1/AMT/ALDH9A1/SPR/ALDH5A1/KLRK1/CX3CR1/KHSRP/SLC44A1	47
BP	GO:0045807	positive regulation of endocytosis	47/4749	153/18670	0.08073	0.2954	0.2403	IL1B/VEGFA/RAB31/PPARG/ITGA2/SIRPA/CLEC7A/ANXA2P2/HIP1/TNF/SERPINE1/ANXA2/IL2RB/MERTK/CLIP3/ARRB1/IL2RG/CLU/AXL/SFRP4/PPT1/HIP1R/SH3GL1/CCL2/IL15RA/PICK1/PTPRC/CD300LF/CD47/ACTN4/FLOT1/VTN/LRP1/RAB27A/RAPGEF1/FPR2/FMR1/CD151/ATAD1/CYBA/LMAN2/DNM1/IL4/LDLRAP1/BCR/NTF3/DLL1	47
BP	GO:0090316	positive regulation of intracellular protein transport	47/4749	153/18670	0.08073	0.2954	0.2403	IL1B/GTSE1/KIF20B/CAMK1/CDK5/YWHAE/RBM22/SORL1/USP36/SAE1/TENM1/SEC16A/B3GAT3/SFN/PAK1/BAP1/PDCD5/HPS4/TCF7L2/PINK1/BCAP31/TMEM30A/CHP1/EMD/EFCAB7/ERBB2/OAZ2/RAC2/ECT2/EDEM2/ZC3H12A/BAG3/GSK3A/RHOU/UBL5/PRNP/HSPA1L/OAZ1/FZD5/STOM/ZFAND1/RUFY3/TGFB1/BCAS3/MAPK1/SREBF2/FYN	47
BP	GO:0002576	platelet degranulation	40/4749	128/18670	0.08084	0.2954	0.2403	CD109/VEGFA/PDGFA/TEX264/CD9/PROS1/SERPINE1/F5/P2RX1/CLU/TGFB3/CFD/CTSW/ITIH3/PHACTR2/QSOX1/ANXA5/ACTN4/A2M/FERMT3/ENDOD1/TIMP1/CYB5R1/WDR1/SRGN/SERPING1/RARRES2/ALDOA/CHID1/BRPF3/VTI1B/ITGA2B/TIMP3/ISLR/SERPINA4/PPBP/OLA1/TGFB1/PDGFB/VEGFC	40
BP	GO:0032606	type I interferon production	40/4749	128/18670	0.08084	0.2954	0.2403	IRF7/RELB/IL10/ISG15/TLR8/TREX1/SIRPA/TIRAP/HMGB1/NFKB2/PQBP1/IRF5/TLR4/TRIM25/MMP12/TRAIP/HAVCR2/UBA7/XRCC6/NPLOC4/POLR3H/CYLD/TLR2/FLOT1/DTX4/IRAK1/DHX33/RNF216/AZI2/NLRC3/IRF3/IFI16/RIPK2/DDX41/PTPRS/CRCP/STAT1/POLR3GL/ZCCHC3/TRIM15	40
BP	GO:0071166	ribonucleoprotein complex localization	40/4749	128/18670	0.08084	0.2954	0.2403	SEC13/U2AF1/NUP98/SMG5/POLDIP3/IWS1/RNPS1/RPS15/ENY2/SRSF4/NUP153/UPF1/MAGOHB/ABCE1/ALKBH5/SUPT6H/PRPF31/NUP88/THOC3/U2AF1L4/POM121C/NUP205/RAE1/NUP50/DHX38/SDAD1/MAGOH/CPSF1/SMG6/GLE1/NUP93/DDX19A/CDC40/NUP35/AAAS/NCBP2/NUP62/SEH1L/YTHDC1/NXF3	40
BP	GO:0045739	positive regulation of DNA repair	22/4749	65/18670	0.08109	0.2957	0.2406	FOXM1/HMGB1/NUDT16/DTX3L/UBE2N/RPS3/EYA2/CBX8/ERCC8/TIMELESS/RNF8/BRCC3/XRCC1/WRAP53/DDX11/MAD2L2/FAM168A/WAS/MGMT/HDAC10/RNF168/SIRT1	22
BP	GO:0050854	regulation of antigen receptor-mediated signaling pathway	22/4749	65/18670	0.08109	0.2957	0.2406	PTPN6/CBFB/LGALS3/CEACAM1/BLK/BTN2A2/GCSAM/LILRB4/RPS3/PTPRC/EZR/CYLD/NFAM1/DUSP22/KCNN4/PLCL2/THY1/CD19/PRNP/PRKCB/GCSAML/SLC39A10	22
BP	GO:0072678	T cell migration	22/4749	65/18670	0.08109	0.2957	0.2406	CXCL13/WNK1/ICAM1/CCL20/CD200/CXCL10/DOCK8/CCR6/RIPK3/CCR2/SLC12A2/CCL3/S1PR1/CCL2/AIF1/CXCL16/IL27RA/CRK/CD99L2/DEFA1B/ZAP70/CCL27	22
BP	GO:0032469	endoplasmic reticulum calcium ion homeostasis	9/4749	22/18670	0.08178	0.2957	0.2406	PML/KCTD17/BAX/TGM2/ATP2A1/HERPUD1/BCAP31/BAK1/CAMK2D	9
BP	GO:0032727	positive regulation of interferon-alpha production	9/4749	22/18670	0.08178	0.2957	0.2406	IRF7/TLR8/HMGB1/IRF5/TLR4/MMP12/IRF3/RIPK2/STAT1	9
BP	GO:0034311	diol metabolic process	9/4749	22/18670	0.08178	0.2957	0.2406	SGPP1/DHFR/GBA/ACER1/ACER2/ASAH2/ASAH2B/SPHK2/SPR	9
BP	GO:0034643	establishment of mitochondrion localization, microtubule-mediated	9/4749	22/18670	0.08178	0.2957	0.2406	UXT/UBB/MAP1S/LRPPRC/RHOT2/NEFL/UCHL1/SYBU/MGARP	9
BP	GO:0046058	cAMP metabolic process	9/4749	22/18670	0.08178	0.2957	0.2406	PDE4A/ADCY4/PDE4D/PDE4B/PTHLH/ADCY6/ADCY3/PDE7B/ADCY9	9
BP	GO:0047497	mitochondrion transport along microtubule	9/4749	22/18670	0.08178	0.2957	0.2406	UXT/UBB/MAP1S/LRPPRC/RHOT2/NEFL/UCHL1/SYBU/MGARP	9
BP	GO:0051457	maintenance of protein location in nucleus	9/4749	22/18670	0.08178	0.2957	0.2406	BCL3/CDK5/PML/SUN2/PARK7/TOPORS/ARL2BP/ARL2/BARD1	9
BP	GO:0097205	renal filtration	9/4749	22/18670	0.08178	0.2957	0.2406	MCAM/SULF2/ITGA3/MYO1E/CD34/F2R/PDGFB/XPNPEP3/GJA5	9
BP	GO:0002224	toll-like receptor signaling pathway	45/4749	146/18670	0.08202	0.2957	0.2406	IRF7/GRAMD4/TYRO3/IRF4/TLR8/TIRAP/UNC93B1/HMGB1/TLR4/LILRA2/RSAD2/BTK/HAVCR2/UBB/TRIL/CTSB/IRAK3/RPS27A/LRRC14/CD300LF/RFTN1/UBA52/TLR2/FLOT1/TANK/IRAK1/TLR6/TAB1/NFKBIA/PRKCE/NFKBIL1/CYBA/IRF3/BIRC3/TNIP3/PIK3C3/S100A8/RIPK2/ESR1/MAPKAPK2/PTPRS/COLEC12/TRAF6/PIK3R4/PJA2	45
BP	GO:0035264	multicellular organism growth	45/4749	146/18670	0.08202	0.2957	0.2406	PLAC8/STIL/KLF2/BBS2/PTCH1/SOCS2/GAMT/ATF5/CSF1/MTOR/PLEKHA1/STAT3/FXN/PDE4D/PLS1/GNAS/ARID5B/WWTR1/KAT2A/SLC25A25/MBD5/APBA2/EZR/TNKS2/MKKS/SLC4A10/CACNA2D2/TAF10/FKBP8/ERCC2/SH3PXD2B/WDR11/GHRL/GIGYF2/GPR21/STAT5A/ZFP36L1/XPA/ATRN/ATM/WDR48/RARA/SLC12A5/ANKRD11/ERCC1	45
BP	GO:0042542	response to hydrogen peroxide	45/4749	146/18670	0.08202	0.2957	0.2406	PPIF/TXNIP/CDK1/NR4A3/FOSL1/KLF2/IL10/KLF4/LDHA/SIRPA/MAP1LC3A/GPX1/PLEKHA1/RIPK3/FXN/SRC/HMOX1/PRDX3/AXL/RPS3/HBA2/NQO1/FOXO1/SDC1/CBX8/MAP3K5/PINK1/EZH2/BAK1/ARG1/PARK7/STK25/JUN/PPP5C/UBE3A/CRK/ECT2/HBB/STAT1/NET1/ADAM9/BAD/FYN/SIRT1/DUSP1	45
BP	GO:2000241	regulation of reproductive process	45/4749	146/18670	0.08202	0.2957	0.2406	LIF/NOTCH1/ASPM/TTK/AURKA/PHLDA2/TRIP13/CDC20/CDC25A/PPP2R1A/FBXO43/UBE2B/CDC25C/HYAL3/MSX1/ASTL/SRC/SNAI1/FBXO5/OVGP1/STK3/NRK/WDR77/RXRA/CNR1/ACVR1C/TIMP1/CITED2/PAEP/SFRP1/SIRT2/ESR1/PRKACB/ANKRD31/P2RY1/C1QBP/INSR/NUPR1/EAF2/PLCB1/CDC25B/PLB1/PTAFR/GCM1/DUSP1	45
BP	GO:0044706	multi-multicellular organism process	66/4749	222/18670	0.08235	0.2957	0.2406	VDR/LIF/IL1B/ITGA2/FOSL1/ITGA3/UBE2A/PTGIS/SPP1/MMP9/LGALS9/PRDM1/FOSB/DHODH/ADRA2B/TEAD3/MTOR/HYAL3/PRDX3/P2RX1/PAM/HAVCR2/TGFB3/PTHLH/CTSB/OVGP1/BYSL/NAMPT/UPRT/ADIPOR2/NRK/ARG1/RXRA/CNR1/ARID1A/SLC38A2/CYP27B1/SH3PXD2B/ACVR1C/TIMP1/RECK/RPL29/IDO1/ARNTL/DDR1/BSG/ACSL4/ADM/GHRL/ESR1/LNPEP/C1QBP/SPHK2/HEXB/PCSK5/HPGD/FOS/PSG11/NPFF/PPARD/TGFB1/RARA/MAPK1/CLDN4/PTAFR/POLR1B	66
BP	GO:0042752	regulation of circadian rhythm	36/4749	114/18670	0.08254	0.2957	0.2406	CDK1/CSF2/PPARG/TOP2A/ADORA2A/PSPC1/SFPQ/ARNTL2/PML/PPP1CB/USP9X/MTOR/NKX2-1/CRY1/PER2/ZFHX3/CRTC1/BHLHE40/RORC/EZH2/TIMELESS/RBM4B/UBE3A/FBXW11/PHLPP1/ARNTL/KLF10/SIAH2/NPS/BTRC/GHRL/PASD1/GNAQ/MTA1/PER3/ATG7	36
BP	GO:0045333	cellular respiration	58/4749	193/18670	0.08293	0.2957	0.2406	CDK1/NR4A3/TREX1/PRELID1/COX8A/CBFA2T3/SLC25A23/FXN/CCNB1/VCP/OGDH/BLOC1S1/PDHB/NDUFB11/COX6A1/UQCRC1/SLC25A25/NOA1/PRDM16/NDUFB8/MDH2/BID/PINK1/SLC25A14/FASTKD2/DLST/NDUFS1/DLAT/SIRT3/NDUFS7/PARK7/CS/ACO1/ETFA/NDUFB10/MYBBP1A/NDUFC1/NDUFA9/IDH3B/COX4I1/FASTKD3/UQCR11/IL4/ME3/POLG2/ISCU/NDUFA12/COQ10A/ETFB/NNT/TBRG4/D2HGDH/TAZ/NDUFA4/NDUFB2/ALDH5A1/NDUFA13/NDUFAF2	58
BP	GO:0003183	mitral valve morphogenesis	5/4749	10/18670	0.08327	0.2957	0.2406	TWIST1/NOTCH1/DCHS1/SMAD6/ZFPM1	5
BP	GO:0006307	DNA dealkylation involved in DNA repair	5/4749	10/18670	0.08327	0.2957	0.2406	MPG/ALKBH2/ALKBH5/MGMT/ALKBH3	5
BP	GO:0006751	glutathione catabolic process	5/4749	10/18670	0.08327	0.2957	0.2406	CHAC1/CHAC2/GGT1/GGTLC2/GGT7	5
BP	GO:0010918	positive regulation of mitochondrial membrane potential	5/4749	10/18670	0.08327	0.2957	0.2406	CTNS/VCP/BID/NNT/BAD	5
BP	GO:0014049	positive regulation of glutamate secretion	5/4749	10/18670	0.08327	0.2957	0.2406	ADORA2A/SYT4/CCK/NTSR1/P2RX7	5
BP	GO:0015801	aromatic amino acid transport	5/4749	10/18670	0.08327	0.2957	0.2406	SLC7A5/SLC3A2/OCA2/SLC36A4/SLC16A10	5
BP	GO:0030388	fructose 1,6-bisphosphate metabolic process	5/4749	10/18670	0.08327	0.2957	0.2406	PFKP/ALDOC/ALDOA/PFKL/ALDOB	5
BP	GO:0031848	protection from non-homologous end joining at telomere	5/4749	10/18670	0.08327	0.2957	0.2406	TFIP11/ACD/XRCC1/ERCC1/TERF2	5
BP	GO:0032463	negative regulation of protein homooligomerization	5/4749	10/18670	0.08327	0.2957	0.2406	SRC/CLU/GBA/PEX5/CRBN	5
BP	GO:0032926	negative regulation of activin receptor signaling pathway	5/4749	10/18670	0.08327	0.2957	0.2406	SKI/DAND5/LEMD3/DACT2/CER1	5
BP	GO:0033210	leptin-mediated signaling pathway	5/4749	10/18670	0.08327	0.2957	0.2406	BBS2/STAT3/MKKS/ADIPOR1/SIRT1	5
BP	GO:0035999	tetrahydrofolate interconversion	5/4749	10/18670	0.08327	0.2957	0.2406	MTHFD2/MTHFD1L/TYMS/MTHFS/MTHFD1	5
BP	GO:0039530	MDA-5 signaling pathway	5/4749	10/18670	0.08327	0.2957	0.2406	IRF7/IRF3/C1QBP/ANKRD17/USP17L2	5
BP	GO:0042758	long-chain fatty acid catabolic process	5/4749	10/18670	0.08327	0.2957	0.2406	ADTRP/ABCD1/AIG1/GLYATL2/CYP4F12	5
BP	GO:0043379	memory T cell differentiation	5/4749	10/18670	0.08327	0.2957	0.2406	BCL6/TNFSF4/IL12RB1/CD46/IL23A	5
BP	GO:0043471	regulation of cellular carbohydrate catabolic process	5/4749	10/18670	0.08327	0.2957	0.2406	PGAM1/PPP1CB/GSK3A/PHKG2/PPP1R3B	5
BP	GO:0045657	positive regulation of monocyte differentiation	5/4749	10/18670	0.08327	0.2957	0.2406	FES/CSF1/CD74/JUN/ZFP36L1	5
BP	GO:0046498	S-adenosylhomocysteine metabolic process	5/4749	10/18670	0.08327	0.2957	0.2406	GAMT/MRI1/MTRR/GNMT/ENOPH1	5
BP	GO:0051593	response to folic acid	5/4749	10/18670	0.08327	0.2957	0.2406	TYMS/ASCL1/GSN/OGG1/MGMT	5
BP	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain	5/4749	10/18670	0.08327	0.2957	0.2406	BRD4/CCNK/GTF2H1/PPIL4/GTF2H5	5
BP	GO:0090557	establishment of endothelial intestinal barrier	5/4749	10/18670	0.08327	0.2957	0.2406	ICAM1/TJP2/RAPGEF2/PTPRS/FASN	5
BP	GO:0090715	immunological memory formation process	5/4749	10/18670	0.08327	0.2957	0.2406	BCL6/TNFSF4/IL12RB1/CD46/IL23A	5
BP	GO:0106049	regulation of cellular response to osmotic stress	5/4749	10/18670	0.08327	0.2957	0.2406	SLC25A23/ARHGEF2/MICU1/BDKRB2/BAD	5
BP	GO:1990535	neuron projection maintenance	5/4749	10/18670	0.08327	0.2957	0.2406	ABCD1/ABCD2/PRNP/MAP1A/INSR	5
BP	GO:2000109	regulation of macrophage apoptotic process	5/4749	10/18670	0.08327	0.2957	0.2406	IRF7/CCR5/CDKN2A/NOD2/SIRT1	5
BP	GO:2000665	regulation of interleukin-13 secretion	5/4749	10/18670	0.08327	0.2957	0.2406	LGALS9/TNFRSF21/PAEP/LILRA5/GATA3	5
BP	GO:2001214	positive regulation of vasculogenesis	5/4749	10/18670	0.08327	0.2957	0.2406	CEACAM1/RAPGEF2/ADM/CD34/HIF1AN	5
BP	GO:0071260	cellular response to mechanical stimulus	26/4749	79/18670	0.0834	0.2957	0.2406	IL1B/ITGA2/RAC1/TLR8/TNFRSF8/TLR4/GADD45A/TMEM150C/MAP3K2/PTGER4/KCNJ2/FAS/TNFRSF10B/BAK1/CASP8AP2/SLC38A2/CHEK1/PIEZO1/CYBA/BAG3/MAP2K4/IL13/GCLC/CNN2/TGFB1/BAD	26
BP	GO:0007260	tyrosine phosphorylation of STAT protein	28/4749	86/18670	0.08381	0.2957	0.2406	LIF/IL18/CSF2/IL21/CSF1R/TNFRSF18/CNTF/NF2/PPP2R1A/TNF/STAT3/PARP14/SOCS3/FLT3/PTK6/PPP2CA/OSM/GGNBP2/PIBF1/CNOT7/IL13/IL20/IL4/ARL2BP/FER/JAK3/FYN/IL23A	28
BP	GO:0006576	cellular biogenic amine metabolic process	19/4749	55/18670	0.08394	0.2957	0.2406	SMOX/SMS/MOXD1/SARDH/GDPD1/SAT1/OAZ3/BHMT/OAZ2/IDO1/TPH1/SATL1/GDE1/AANAT/DHPS/ALDH7A1/OAZ1/HDAC10/SLC44A1	19
BP	GO:0010823	negative regulation of mitochondrion organization	19/4749	55/18670	0.08394	0.2957	0.2406	PPIF/PRELID1/HSPA1A/NOL3/GPX1/BAG4/LMNA/TSPO/FXN/CLU/PINK1/SLC25A5/BCL2L1/BAG3/FZD9/PAM16/PSMD10/ATG7/OMA1	19
BP	GO:0045620	negative regulation of lymphocyte differentiation	19/4749	55/18670	0.08394	0.2957	0.2406	HMGB3/BCL6/CBFB/TNFSF4/HMGB1/FOXP3/CTLA4/IL4R/SMAD7/CD74/HLX/PGLYRP3/LAG3/ERBB2/DTX1/ZC3H12A/NRARP/SFRP1/JAK3	19
BP	GO:0032388	positive regulation of intracellular transport	64/4749	215/18670	0.08419	0.2957	0.2406	IL1B/GTSE1/KIF20B/SPAG5/CAMK1/CDK5/ANXA2P2/YWHAE/RBM22/GAB2/ANXA2/IL4R/SORL1/USP36/SAE1/TENM1/SEC16A/B3GAT3/NUMA1/SFN/ATP2A1/PAK1/BAP1/PDCD5/HPS4/TCF7L2/PINK1/EZR/BCAP31/TBC1D20/TMEM30A/CNR1/CHP1/EMD/EFCAB7/ERBB2/OAZ2/RAC2/ECT2/EDEM2/ZC3H12A/BAG3/GSK3A/IL13/RHOU/UBL5/PRNP/LDLRAP1/HSPA1L/CPSF6/SPHK2/CACNB2/OAZ1/RBM27/FZD5/STOM/NCBP2/ZFAND1/RUFY3/TGFB1/BCAS3/MAPK1/SREBF2/FYN	64
BP	GO:0001832	blastocyst growth	8/4749	19/18670	0.08435	0.2957	0.2406	BRCA2/PELO/GINS1/GINS4/SALL4/SBDS/ZNF830/PRPF19	8
BP	GO:0002566	somatic diversification of immune receptors via somatic mutation	8/4749	19/18670	0.08435	0.2957	0.2406	EXO1/MSH6/PMS2P1/POLQ/AICDA/PMS2P5/SAMHD1/POLM	8
BP	GO:0006534	cysteine metabolic process	8/4749	19/18670	0.08435	0.2957	0.2406	MPST/TST/GGT1/CTH/MRI1/MTRR/ENOPH1/GCLC	8
BP	GO:0007625	grooming behavior	8/4749	19/18670	0.08435	0.2957	0.2406	CTNS/PPT1/HPRT1/DRD1/QRFP/APRT/SLITRK5/DLG4	8
BP	GO:0032011	ARF protein signal transduction	8/4749	19/18670	0.08435	0.2957	0.2406	CYTH2/PSD4/MAPRE2/IQSEC1/PSD3/GBF1/CYTH1/IQSEC3	8
BP	GO:0032012	regulation of ARF protein signal transduction	8/4749	19/18670	0.08435	0.2957	0.2406	CYTH2/PSD4/MAPRE2/IQSEC1/PSD3/GBF1/CYTH1/IQSEC3	8
BP	GO:0032095	regulation of response to food	8/4749	19/18670	0.08435	0.2957	0.2406	BBS2/MTOR/NENF/CCK/MKKS/NUCB2/GHRL/NPFF	8
BP	GO:0034312	diol biosynthetic process	8/4749	19/18670	0.08435	0.2957	0.2406	DHFR/GBA/ACER1/ACER2/ASAH2/ASAH2B/SPHK2/SPR	8
BP	GO:0060252	positive regulation of glial cell proliferation	8/4749	19/18670	0.08435	0.2957	0.2406	IL1B/TNF/E2F1/MTOR/TSPO/ETV5/PRKCI/LTA	8
BP	GO:1902170	cellular response to reactive nitrogen species	8/4749	19/18670	0.08435	0.2957	0.2406	CCNA2/CFLAR/CDK2/FOXO1/MAP3K5/CRK/TRAF2/MTR	8
BP	GO:2000042	negative regulation of double-strand break repair via homologous recombination	8/4749	19/18670	0.08435	0.2957	0.2406	PARPBP/RMI2/TP53BP1/POLQ/MAGEF1/RECQL5/MAD2L2/HELB	8
BP	GO:2000251	positive regulation of actin cytoskeleton reorganization	8/4749	19/18670	0.08435	0.2957	0.2406	FES/HCK/CDK5/NTRK3/NTF3/BCAS3/CDC42/CCL27	8
BP	GO:2000696	regulation of epithelial cell differentiation involved in kidney development	8/4749	19/18670	0.08435	0.2957	0.2406	LIF/MMP9/WWTR1/PRKX/YAP1/ADIPOQ/STAT1/GATA3	8
BP	GO:0001893	maternal placenta development	13/4749	35/18670	0.08465	0.2957	0.2406	VDR/LIF/PTGIS/SPP1/PRDM1/PRDX3/CTSB/RXRA/CYP27B1/BSG/GHRL/PPARD/MAPK1	13
BP	GO:0002701	negative regulation of production of molecular mediator of immune response	13/4749	35/18670	0.08465	0.2957	0.2406	IL10/BCL6/TNF/FOXP3/SMAD7/HMOX1/BST2/TGFB3/IRAK3/ARG1/TGFB1/JAK3/CD96	13
BP	GO:1901385	regulation of voltage-gated calcium channel activity	13/4749	35/18670	0.08465	0.2957	0.2406	GEM/REM1/KCNE3/PDE4B/SRI/GPR35/REM2/STAC3/STAC/FMR1/AHNAK/CACNB2/EHD3	13
BP	GO:1990774	tumor necrosis factor secretion	13/4749	35/18670	0.08465	0.2957	0.2406	LGALS9/HMGB1/LILRA2/HAVCR2/IL27RA/DEFB114/SYT11/ZC3H12A/LILRA5/IFNGR1/GHRL/SPHK2/FZD5	13
BP	GO:0010569	regulation of double-strand break repair via homologous recombination	16/4749	45/18670	0.08553	0.2957	0.2406	SIRT6/RAD51/RAD51AP1/PARPBP/RMI2/TP53BP1/POLQ/MAGEF1/FIGNL1/TIMELESS/RECQL5/CHEK1/WRAP53/MAD2L2/HELB/WAS	16
BP	GO:0032570	response to progesterone	16/4749	45/18670	0.08553	0.2957	0.2406	TXNIP/FOSL1/FOSB/TYMS/TSPO/SRC/TGFB3/TLR2/UBE3A/PTGER2/YAP1/FOS/CATSPER2/TGFB1/CLDN4/BAD	16
BP	GO:0045581	negative regulation of T cell differentiation	16/4749	45/18670	0.08553	0.2957	0.2406	BCL6/CBFB/TNFSF4/HMGB1/FOXP3/CTLA4/IL4R/SMAD7/CD74/HLX/LAG3/ERBB2/DTX1/ZC3H12A/NRARP/JAK3	16
BP	GO:0070316	regulation of G0 to G1 transition	16/4749	45/18670	0.08553	0.2957	0.2406	RBBP8/E2F1/UXT/RAD51/RYBP/CBX5/HLA-G/PHC3/EED/EZH2/TFDP2/PCGF6/CHEK1/RRM2/MAX/BMI1	16
BP	GO:0045471	response to ethanol	39/4749	125/18670	0.08558	0.2957	0.2406	CDK1/ICAM1/SPI1/TYMS/EIF4EBP1/SETD7/GSN/CYBB/RPL10A/STAT3/ABAT/GGH/NTRK3/SLC2A4/NQO1/KCNMB1/RGS19/OXCT1/BAK1/TP53INP1/CNR1/PRKCE/RPS4X/TBXA2R/IL13/BGLAP/S100A8/ADIPOQ/HPGD/CCL7/OGG1/MGMT/RARA/CCND1/SETDB1/TUFM/GATA3/BAD/FYN	39
BP	GO:0000394	RNA splicing, via endonucleolytic cleavage and ligation	7/4749	16/18670	0.08604	0.2957	0.2406	TSEN2/FAM98B/TSEN15/TSEN34/TRPT1/ERN1/CPSF1	7
BP	GO:0009208	pyrimidine ribonucleoside triphosphate metabolic process	7/4749	16/18670	0.08604	0.2957	0.2406	AK3/NME4/NME3/CTPS2/UCK2/NME9/NME2	7
BP	GO:0010875	positive regulation of cholesterol efflux	7/4749	16/18670	0.08604	0.2957	0.2406	ABCG1/PTCH1/ABCA1/LRP1/NFKBIA/ADIPOQ/SIRT1	7
BP	GO:0033631	cell-cell adhesion mediated by integrin	7/4749	16/18670	0.08604	0.2957	0.2406	CXCL13/WNK1/SWAP70/FERMT3/PIEZO1/CD3E/ADAM9	7
BP	GO:0035372	protein localization to microtubule	7/4749	16/18670	0.08604	0.2957	0.2406	KIF20B/MAPRE2/DVL1/MID1/MID2/MAP1A/CHAMP1	7
BP	GO:0036124	histone H3-K9 trimethylation	7/4749	16/18670	0.08604	0.2957	0.2406	SMARCB1/LMNA/ZNF304/DMRTC2/ARID4A/KDM4C/SIRT1	7
BP	GO:0042033	chemokine biosynthetic process	7/4749	16/18670	0.08604	0.2957	0.2406	EGR1/IL1B/IL18/TNF/HMOX1/CD74/SIGIRR	7
BP	GO:0045618	positive regulation of keratinocyte differentiation	7/4749	16/18670	0.08604	0.2957	0.2406	VDR/NOTCH1/NUMA1/CYP27B1/IL20/TRIM16/NME2	7
BP	GO:0050755	chemokine metabolic process	7/4749	16/18670	0.08604	0.2957	0.2406	EGR1/IL1B/IL18/TNF/HMOX1/CD74/SIGIRR	7
BP	GO:0051447	negative regulation of meiotic cell cycle	7/4749	16/18670	0.08604	0.2957	0.2406	LIF/TTK/TRIP13/FBXO43/FBXO5/PRKACB/DUSP1	7
BP	GO:0055012	ventricular cardiac muscle cell differentiation	7/4749	16/18670	0.08604	0.2957	0.2406	CDK1/MYH10/LMNA/CCNB1/RXRA/BMP10/RARA	7
BP	GO:0060965	negative regulation of gene silencing by miRNA	7/4749	16/18670	0.08604	0.2957	0.2406	PPARG/ZC3H12A/NEAT1/ELAVL1/ESR1/TGFB1/NCOR1	7
BP	GO:0061684	chaperone-mediated autophagy	7/4749	16/18670	0.08604	0.2957	0.2406	CTSA/ATP13A2/CLU/EEF1A1/EEF1A2/BAG3/ATG7	7
BP	GO:0070200	establishment of protein localization to telomere	7/4749	16/18670	0.08604	0.2957	0.2406	BRCA2/CCT5/TERF1/ACD/POT1/WRAP53/CCT3	7
BP	GO:0071380	cellular response to prostaglandin E stimulus	7/4749	16/18670	0.08604	0.2957	0.2406	PPARG/TNFSF4/PTGER4/ADCY6/PRKCE/PTGER2/SFRP1	7
BP	GO:0071732	cellular response to nitric oxide	7/4749	16/18670	0.08604	0.2957	0.2406	CCNA2/CFLAR/CDK2/FOXO1/CRK/TRAF2/MTR	7
BP	GO:0090083	regulation of inclusion body assembly	7/4749	16/18670	0.08604	0.2957	0.2406	HSPA2/HSPA1A/SORL1/CLU/DNAJB6/DNAJB2/PSMC5	7
BP	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	7/4749	16/18670	0.08604	0.2957	0.2406	ZNF385A/CD74/TAF9B/MUC1/BCL2L12/CD44/SIRT1	7
BP	GO:0002281	macrophage activation involved in immune response	6/4749	13/18670	0.08613	0.2957	0.2406	TREX1/GRN/SBNO2/HAVCR2/PRKCE/TYROBP	6
BP	GO:0006384	transcription initiation from RNA polymerase III promoter	6/4749	13/18670	0.08613	0.2957	0.2406	GTF3C4/SNAPC5/BRF2/POLR3H/BDP1/CRCP	6
BP	GO:0006596	polyamine biosynthetic process	6/4749	13/18670	0.08613	0.2957	0.2406	SMOX/SMS/SAT1/OAZ3/OAZ2/OAZ1	6
BP	GO:0008298	intracellular mRNA localization	6/4749	13/18670	0.08613	0.2957	0.2406	ZNF385A/ZFP36/MEX3D/EXOSC2/ZFP36L1/A1CF	6
BP	GO:0009650	UV protection	6/4749	13/18670	0.08613	0.2957	0.2406	FEN1/GPX1/ERCC5/ERCC2/XPA/ERCC1	6
BP	GO:0014745	negative regulation of muscle adaptation	6/4749	13/18670	0.08613	0.2957	0.2406	KLF4/NOL3/MTOR/LMNA/FOXO1/ATP2B4	6
BP	GO:0031650	regulation of heat generation	6/4749	13/18670	0.08613	0.2957	0.2406	IL1B/TNF/ARRDC3/ABAT/CNR1/TNFSF11	6
BP	GO:0032096	negative regulation of response to food	6/4749	13/18670	0.08613	0.2957	0.2406	BBS2/NENF/CCK/MKKS/NUCB2/NPFF	6
BP	GO:0032099	negative regulation of appetite	6/4749	13/18670	0.08613	0.2957	0.2406	BBS2/NENF/CCK/MKKS/NUCB2/NPFF	6
BP	GO:0033127	regulation of histone phosphorylation	6/4749	13/18670	0.08613	0.2957	0.2406	TWIST1/IL1B/UBE2B/CCNB1/FMR1/ATM	6
BP	GO:0043201	response to leucine	6/4749	13/18670	0.08613	0.2957	0.2406	MTOR/PIK3C3/UBR2/KLHL22/SESN2/PDX1	6
BP	GO:0043248	proteasome assembly	6/4749	13/18670	0.08613	0.2957	0.2406	POMP/PSMD9/PSMG4/PSMD5/PSMD10/PSMD11	6
BP	GO:0043301	negative regulation of leukocyte degranulation	6/4749	13/18670	0.08613	0.2957	0.2406	CEACAM1/LGALS9/CCR2/HMOX1/RABGEF1/BCR	6
BP	GO:0045078	positive regulation of interferon-gamma biosynthetic process	6/4749	13/18670	0.08613	0.2957	0.2406	EBI3/CD276/IL21/TLR8/CLEC7A/ZFPM1	6
BP	GO:0046831	regulation of RNA export from nucleus	6/4749	13/18670	0.08613	0.2957	0.2406	IWS1/NUP153/SUPT6H/CPSF6/RBM27/NCBP2	6
BP	GO:0048505	regulation of timing of cell differentiation	6/4749	13/18670	0.08613	0.2957	0.2406	NOTCH1/ASCL1/FGF9/RBPJ/GDPD5/DLL1	6
BP	GO:0060712	spongiotrophoblast layer development	6/4749	13/18670	0.08613	0.2957	0.2406	LIF/PHLDA2/SOCS3/NRK/ADM/ZFP36L1	6
BP	GO:0061430	bone trabecula morphogenesis	6/4749	13/18670	0.08613	0.2957	0.2406	PLXNB1/SBNO2/WNT10B/PPARGC1B/SFRP1/SEMA4D	6
BP	GO:0070208	protein heterotrimerization	6/4749	13/18670	0.08613	0.2957	0.2406	COL6A2/COL6A1/C1QTNF6/ADIPOQ/WIZ/NUP62	6
BP	GO:0070986	left/right axis specification	6/4749	13/18670	0.08613	0.2957	0.2406	NOTCH1/IFT172/EPB41L5/CITED2/SETDB2/DLL1	6
BP	GO:0090481	pyrimidine nucleotide-sugar transmembrane transport	6/4749	13/18670	0.08613	0.2957	0.2406	SLC35A2/SLC35E4/SLC35B1/SLC35D2/SLC35D1/SLC35B4	6
BP	GO:1901836	regulation of transcription of nucleolar large rRNA by RNA polymerase I	6/4749	13/18670	0.08613	0.2957	0.2406	MTOR/SMARCB1/SMARCA4/NCL/DDX11/IPPK	6
BP	GO:0032922	circadian regulation of gene expression	21/4749	62/18670	0.0863	0.2959	0.2408	EGR1/RELB/PML/PPP1CB/CRY1/ATF4/PER2/ZFHX3/BHLHE40/RORC/NAMPT/RBM4B/KDM8/MYBBP1A/ARNTL/BHLHE41/KDM5A/MTA1/PER3/MC3R/SIRT1	21
BP	GO:1905268	negative regulation of chromatin organization	21/4749	62/18670	0.0863	0.2959	0.2408	TWIST1/SPI1/SKI/UBE2B/FOXP3/SMARCB1/BCOR/SUPT6H/AICDA/ATAD2/MLLT6/TAF7/KDM5A/SPHK2/CTBP1/KDM4C/ZNF451/ASF1A/PHF8/USP17L2/SIRT1	21
BP	GO:0043574	peroxisomal transport	23/4749	69/18670	0.08782	0.301	0.2449	MPV17/USP9X/ABCD1/SLC27A2/UBB/HMGCL/EPHX2/ACOX2/TYSND1/RPS27A/ACOT8/UBA52/AMACR/PEX2/PEX3/PEX5/GSTK1/NUDT19/PECR/PEX13/PEX1/DECR2/ZFAND6	23
BP	GO:0055074	calcium ion homeostasis	133/4749	471/18670	0.08791	0.3011	0.245	VDR/CXCL13/GNA15/FPR1/CXCR6/PTPN6/NMB/FPR3/CCR1/CDK5/ANXA2P2/CCRL2/YWHAE/CHERP/PML/KCTD17/HMGB1/CDH23/JSRP1/CHRNA10/NCS1/NOL3/BAX/CXCL10/SPPL3/TRPC1/SLC25A23/ANXA2/SWAP70/CCR6/ATP13A1/CCR2/MYO5A/HCRT/CCR4/P2RX1/TGM2/ATP13A4/F2RL2/PDE4D/HTR2A/ATP2A1/CCL3/ATP13A2/PTGER4/SRI/MICU1/CYSLTR1/HERPUD1/PKD2/ATF4/RIC3/EPHX2/CCR5/HTT/S1PR1/GPR33/GPR35/ATP1B1/CASR/GSTO1/TPCN1/PTPRC/BCAP31/CORO1A/TRPM4/RASA3/ANXA5/CXCL9/P2RY10/BAK1/DRD1/FKBP1A/ATP2B4/LRP1/DDIT3/THY1/CD19/BDKRB2/CNR1/NTSR1/SLC24A3/FPR2/TFAP2B/CYP27B1/C3AR1/GPR12/PRKCE/PTGER2/CCR8/CYBA/TMEM203/LACRT/GPR32/TBXA2R/PTGER1/IL13/CALB2/ADM/GHRL/CAMK2D/P2RX5/PRNP/ESR1/F2R/FZD9/LRP6/PRKCB/P2RY1/TRPC7/CCL23/HEXB/CACNB2/TNFSF11/CCL7/NPFF/PLCB1/TGFB1/TMEM64/CCL15/GALR2/SV2A/TRPC5/CDH5/CXCR5/P2RX7/CX3CR1/PDE6B/GIPR/SLC35G1/FYN/DLG4/GTF2I	133
BP	GO:0000422	autophagy of mitochondrion	25/4749	76/18670	0.08871	0.3035	0.247	SQSTM1/BNIP3L/HK2/CTTN/MAP1LC3A/TSPO/USP36/ATG9A/ATP13A2/HTT/AMBRA1/SMURF1/PINK1/GBA/VDAC1/PARK7/ATG2B/GSK3A/WDR45/FUNDC2/VPS13D/FZD5/ATG7/SREBF2/FUNDC1	25
BP	GO:0061726	mitochondrion disassembly	25/4749	76/18670	0.08871	0.3035	0.247	SQSTM1/BNIP3L/HK2/CTTN/MAP1LC3A/TSPO/USP36/ATG9A/ATP13A2/HTT/AMBRA1/SMURF1/PINK1/GBA/VDAC1/PARK7/ATG2B/GSK3A/WDR45/FUNDC2/VPS13D/FZD5/ATG7/SREBF2/FUNDC1	25
BP	GO:0010717	regulation of epithelial to mesenchymal transition	29/4749	90/18670	0.08909	0.3044	0.2476	TWIST1/IL1B/NOTCH1/TGFB1I1/MTOR/SMAD7/SNAI1/NKX2-1/ALX1/TIAM1/TRIM62/SDCBP/TGFB3/WWTR1/JAG1/TCF7L2/CLASP2/EZH2/PPP2CA/ADIPOR1/VASN/LDLRAD4/ZNF703/PHLDB1/SFRP1/GLIPR2/MAD2L2/AXIN2/TGFB1	29
BP	GO:0031058	positive regulation of histone modification	29/4749	90/18670	0.08909	0.3044	0.2476	LIF/IL1B/VEGFA/BCL6/PHF19/FOXP3/SMARCB1/LMNA/NAP1L2/CCNB1/ARRB1/KAT2A/UBE2N/RNF40/ZNF304/PINK1/EED/BRD4/MUC1/FMR1/C6orf89/DMRTC2/TADA2A/SPHK2/CTBP1/ATM/TGFB1/GATA3/SIRT1	29
BP	GO:1901879	regulation of protein depolymerization	27/4749	83/18670	0.08909	0.3044	0.2476	CAPZB/GSN/CKAP2/ASPH/SWAP70/TMOD2/CAPG/ARHGEF2/PDXP/ADD3/SPTBN1/FGF13/CLASP2/TRIOBP/TWF2/CFL1/SPTAN1/MID1/CAPZA1/MAP1S/TRIM54/WDR1/VILL/MAP1A/APC/SEMA5A/ADD2	27
BP	GO:0046580	negative regulation of Ras protein signal transduction	18/4749	52/18670	0.08934	0.3044	0.2477	ITGA3/BCL6/TIMP2/STAMBP/TNFAIP1/MAPKAP1/ARHGAP35/STMN3/STMN1/RASA3/CCDC125/RAPGEF1/RASA4/RABGEF1/RASAL1/KCTD13/LZTR1/NUP62	18
BP	GO:0050885	neuromuscular process controlling balance	18/4749	52/18670	0.08934	0.3044	0.2477	MYO7A/NR4A3/MYH10/GM2A/CDH23/TPP1/BLOC1S4/TIFAB/USH1G/CAMTA1/GIGYF2/HEXB/BCR/NEFL/NKX6-2/POU4F1/DLG4/RAC3	18
BP	GO:1900024	regulation of substrate adhesion-dependent cell spreading	18/4749	52/18670	0.08934	0.3044	0.2477	NEDD9/RAC1/CORO1C/MYADM/DOCK1/LIMS1/DOCK5/PREX1/TRIOBP/ACTN4/S100A10/UNC13D/CRK/C1QBP/AP1AR/CDC42/HAS2/RAC3	18
BP	GO:2000677	regulation of transcription regulatory region DNA binding	18/4749	52/18670	0.08934	0.3044	0.2477	TWIST1/LIF/DOT1L/KLF4/ZBTB7C/MSX1/SRI/ENHO/PER2/DDIT3/PARK7/SOX11/MAD2L2/TRAF6/ZNF675/TGFB1/POU4F1/GATA3	18
BP	GO:0031297	replication fork processing	12/4749	32/18670	0.08953	0.3044	0.2477	BRCA2/RAD51/TONSL/RFWD3/ZRANB3/SAMHD1/EME1/DDX11/DNA2/ETAA1/NUCKS1/WRN	12
BP	GO:0051385	response to mineralocorticoid	12/4749	32/18670	0.08953	0.3044	0.2477	CDKN1A/FOSL1/FOSB/CYBB/SRC/NTRK3/CYBA/HSD3B2/AANAT/NEFL/FOS/CCND1	12
BP	GO:0070570	regulation of neuron projection regeneration	12/4749	32/18670	0.08953	0.3044	0.2477	PTPRF/KLF4/GRN/CNTF/SPP1/RGMA/NTRK3/SCARF1/LRP1/THY1/PTPRS/RTN4R	12
BP	GO:1900745	positive regulation of p38MAPK cascade	12/4749	32/18670	0.08953	0.3044	0.2477	IL1B/VEGFA/GADD45G/GADD45A/MAP3K5/MAP3K3/ZC3H12A/MINK1/EMC10/MIR181D/NCF1/PJA2	12
BP	GO:2000780	negative regulation of double-strand break repair	12/4749	32/18670	0.08953	0.3044	0.2477	TWIST1/PARPBP/RMI2/TP53BP1/POLQ/MAGEF1/TFIP11/RECQL5/AUNIP/MAD2L2/HELB/OGG1	12
BP	GO:1903844	regulation of cellular response to transforming growth factor beta stimulus	38/4749	122/18670	0.09061	0.3079	0.2505	SKIL/CD109/ITGA3/CDKN2B/LRG1/PMEPA1/SNX25/TGFB1I1/HSPA5/HSPA1A/SKI/DAND5/SMAD7/NKX2-1/CFLAR/SDCBP/UBB/TGFB3/PRDM16/SMAD6/RPS27A/SMURF1/FAM89B/UBA52/LEMD3/VASN/LDLRAD4/EID2/CITED2/SOX11/ZNF703/HTRA4/HTRA1/TGFB1/ZNF451/VEPH1/MIR17HG/SIRT1	38
BP	GO:0033003	regulation of mast cell activation	15/4749	42/18670	0.09092	0.3088	0.2512	NR4A3/FES/LGALS9/GAB2/MILR1/IL4R/HMOX1/CD300LF/CNR1/UNC13D/RAC2/RABGEF1/IL13/FER/SPHK2	15
BP	GO:0071560	cellular response to transforming growth factor beta stimulus	73/4749	249/18670	0.09112	0.3093	0.2516	SKIL/FURIN/CD109/ITGA3/CDKN2B/LRG1/PMEPA1/ZYX/SNX25/TGFB1I1/PML/HSPA5/ARHGEF18/HSPA1A/SKI/USP9X/DAND5/NR3C1/SMAD7/SRC/NKX2-1/CFLAR/SDCBP/UBB/TGFB3/LIMS1/ZFYVE9/PRDM16/PDCD5/SMAD6/STK16/RPS27A/ZFP36L2/SMURF1/FAM89B/UBA52/DUSP22/LEMD3/ARG1/VASN/WWOX/WNT7A/LDLRAD4/JUN/EPB41L5/ACVR1C/ACVR2B/TAB1/CRK/EID2/CITED2/SOX11/ZNF703/HTRA4/SMAD1/SFRP1/LEFTY1/ZFP36L1/HPGD/PARD6A/FOS/HTRA1/ID1/TGFB1/ZNF451/ADAM9/CDH5/VEPH1/MIR17HG/CX3CR1/LRRC32/FYN/SIRT1	73
BP	GO:1904375	regulation of protein localization to cell periphery	36/4749	115/18670	0.09175	0.3113	0.2533	SAPCD2/GPSM2/SQSTM1/ITGA3/CDK5/LGALS3/TNF/AKAP5/PLK1/RANGRF/GRIPAP1/NUMA1/RHOG/CLIP3/PLS1/PTPN9/SPTBN1/EZR/LRRC15/PRKCI/STAC3/LRP1/STAC/EFCAB7/PRKCE/EPB41L2/BCL2L1/VTI1B/PRNP/LDLRAP1/EPB41/GOPC/ARF6/TGFB1/CNST/ACTB	36
BP	GO:0031102	neuron projection regeneration	20/4749	59/18670	0.09189	0.3113	0.2533	PTPRF/KLF4/GRN/CNTF/SPP1/RGMA/TSPO/NTRK3/DHFR/SCARF1/ULK1/LRP1/THY1/JUN/CTNNA1/ADM/PTPRS/MTR/NEFL/RTN4R	20
BP	GO:0043388	positive regulation of DNA binding	20/4749	59/18670	0.09189	0.3113	0.2533	TWIST1/CDCA5/PPARG/ITGA2/KLF4/IRF4/PLAUR/MMP9/HMGB1/SKI/ACD/PARK7/ERCC2/SIRT2/EDF1/TRAF6/TGFB1/POU4F1/GATA3/PDX1	20
BP	GO:0061077	chaperone-mediated protein folding	20/4749	59/18670	0.09189	0.3113	0.2533	HSPA2/HSPA5/HSPA1A/DNAJB5/HSPA9/DNAJB12/CLU/CD74/PDIA4/PDCD5/SGTA/FKBP5/CHORDC1/FKBP1A/HSPA6/DNAJC24/HSPA1L/HSPA14/DNAJB4/DNAJB2	20
BP	GO:0044262	cellular carbohydrate metabolic process	83/4749	286/18670	0.09232	0.3126	0.2543	B3GNT5/TPI1/GK/PHLDA2/IGFBP4/HK1/PFKFB3/GLB1/PGAM1/CBFA2T3/SIRT6/PPP1CB/HK2/PMAIP1/MTOR/STAT3/SLC5A3/SRC/PGM2L1/CSGALNACT1/IDUA/GYG2/PYGM/CRY1/MYOF/PFKFB4/KAT2A/PER2/IGFBP3/GNE/FOXO1/GALK2/RORC/IMPA2/DDIT4/B3GNT2/ENOSF1/PCDH12/GALK1/EXT1/EXTL2/PFKFB2/SLC45A3/ADIPOR1/MAEA/PPP1R3E/PRKAG2/NTSR1/C1QTNF3/EPM2AIP1/PPIP5K1/PRKCE/INPP1/HAS3/GSK3A/PHKG2/BRAF/MOGAT1/B4GALT5/GNMT/ADIPOQ/FGGY/DGAT2/ACACB/P2RY1/RPE/INSR/NUPR1/GUSB/SLC35B4/MANBA/IPPK/PGD/CLK2/HAS2/COX11/PPP1R2/NAGK/SESN2/PTAFR/BAD/PPP1R3B/SIRT1	83
BP	GO:0007269	neurotransmitter secretion	51/4749	169/18670	0.09289	0.3141	0.2556	ADORA2A/PPFIA4/RIMS3/CDK5/SYN1/NCS1/CHRNA5/STX11/HCRT/BLOC1S6/P2RX1/SYT4/SNAP47/HTR2A/CAMK2A/PPT1/SNAP29/PFN2/APBA2/STX1B/DVL1/SCRIB/STX19/DRD1/SNAP23/DTNBP1/WNT7A/PPFIA3/CNR1/FMR1/SYT11/TACR2/ERC2/SNAPIN/NAPB/MCTP2/KCNC4/STX2/RPH3A/DOC2B/CHRNA3/PRKCB/P2RY1/SYN2/CACNB2/FBXL20/LIN7C/SV2A/PDZD11/P2RX7/TRIM9	51
BP	GO:0140056	organelle localization by membrane tethering	51/4749	169/18670	0.09289	0.3141	0.2556	CDK1/KIF24/NEK2/YWHAE/PLK4/PPP2R1A/ODF2/PLK1/CENPJ/TUBB/STX11/B9D2/STX5/BLOC1S6/FGFR1OP/CAMK2A/VPS33B/TUBB4B/RAB3D/SNAP29/SCFD2/STX1B/CEP152/CEP70/SFI1/TCTN1/STX19/STX12/PPFIA3/TUBB4A/MARK4/CEP192/VAMP3/STX16/EXOC6B/ALMS1/HAUS5/VTI1B/ACTR1A/STX2/TUBG1/TMEM67/CETN2/CEP72/RAB15/RALB/CEP89/CEP97/CKAP5/NINL/USO1	51
BP	GO:0071229	cellular response to acid chemical	62/4749	209/18670	0.09293	0.3141	0.2556	EGR1/VEGFA/PPARG/KLF2/NTRK2/KLF4/BCL11A/TNFSF4/TNF/E2F1/CYBB/MTOR/LDLR/WNT10B/LANCL2/FFAR2/CCNB1/SRC/PTGER4/AMIGO1/NTRK3/PTK7/ADCY6/PKD2/COL6A1/FFAR3/PTK6/AQP2/KCNMB1/PINK1/TWF2/ABCA1/SLC38A9/SH3BP4/ABCB4/PRKCE/CEBPB/PTGER2/BCL2L1/CYBA/ZC3H12A/YAP1/SFRP1/CPT1A/LTK/DGAT2/UBR2/LAMTOR4/GCLC/TESC/CPEB1/LAMTOR2/KLHL22/ATM/RRAGB/NDUFA13/RARA/PDGFB/SESN2/PTAFR/FYN/NME2	62
BP	GO:0010038	response to metal ion	104/4749	364/18670	0.0935	0.3156	0.2567	RASGRP2/PPIF/TXNIP/CDK1/WNK1/ICAM1/CASP9/CPNE7/ALOX5AP/MMP9/FOSB/ASCL1/HSPA5/GSN/CRIP1/CYBB/S100A13/CPOX/MAP1LC3A/MT1E/TRPC1/SLC25A23/MT2A/TSPO/FXN/CCNB1/DTYMK/NUDT1/HMOX1/HOMER1/ABAT/GGH/SYT4/PAM/ATP13A2/CPNE5/PKD2/ATF4/NQO1/CASR/AQP2/MT1X/SDC1/KCNMB1/NDRG1/ANXA5/ADAMTS13/MT1H/HVCN1/PPP2CA/ARG1/SUMO1/MT1G/PARK7/JUN/PPP5C/ACO1/RASA4/ACER1/CA2/TNNC1/SYT11/ECT2/TFF1/BSG/RASAL1/CLIC4/BRAF/BGLAP/EIF2AK3/S100A8/CAMK2D/TNFRSF11B/PRNP/AANAT/C1QA/MT1A/CYBRD1/GCLC/MNAT1/MT1B/MT1M/D2HGDH/NCF1/CPNE4/FOS/GSS/OGG1/SYT15/MAPK1/CCND1/ADAM9/PEF1/AMELX/SLC40A1/GDI1/PDX1/P2RX7/GIPR/ERCC1/MT1F/BAD/DLG4/DUSP1	104
BP	GO:0046888	negative regulation of hormone secretion	22/4749	66/18670	0.0935	0.3156	0.2567	LIF/IL1B/PIM3/RAB11FIP1/NMB/ADRA2B/ENY2/CRY1/ENHO/ANXA5/PSMD9/OSM/RAB11FIP3/ACVR1C/TACR2/SFRP1/GHRL/ADIPOQ/RAB11FIP5/PFKL/NPFF/NDUFAF2	22
BP	GO:0051785	positive regulation of nuclear division	22/4749	66/18670	0.0935	0.3156	0.2567	ESPL1/IL1B/CDCA5/UBE2C/CDT1/AURKA/DLGAP5/NUSAP1/UBE2B/MSX1/NUMA1/PHIP/ANAPC11/SIRT2/NSFL1C/INSR/FGF8/SMC5/PLCB1/TGFB1/PDGFB/NUP62	22
BP	GO:0032611	interleukin-1 beta production	32/4749	101/18670	0.09363	0.3157	0.2568	EGR1/IL1B/NLRP3/ACP5/TLR8/HK1/SIRPA/CLEC7A/LGALS9/PML/HMGB1/TLR4/LILRA2/CCL3/CD33/ABCA1/NOD2/TLR6/MNDA/MR1/ZC3H12A/LILRA5/IFI16/GHRL/RIPK2/F2R/TYROBP/CARD8/FZD5/TRIM16/P2RX7/CX3CR1	32
BP	GO:0048661	positive regulation of smooth muscle cell proliferation	32/4749	101/18670	0.09363	0.3157	0.2568	HBEGF/IL18/NR4A3/ITGA2/IL10/MMP9/TNF/MTOR/HMOX1/TGM2/PAK1/FGF9/S1PR1/MAP3K5/NAMPT/MEF2D/AIF1/IRAK1/GNAI2/JUN/RBPMS2/CYBA/IL13/ERN1/LDLRAP1/MNAT1/TRAF6/STAT1/HPGD/ADAMTS1/PDGFB/PTAFR	32
BP	GO:0006029	proteoglycan metabolic process	30/4749	94/18670	0.09428	0.3167	0.2576	SULF2/HS3ST3B1/HS3ST3A1/CHST15/CANT1/HPSE/GPC1/CHPF2/IDS/B3GAT3/CSGALNACT1/IDUA/SLC35D1/TCF7L2/B3GALT6/COL11A1/SPOCK3/CHST7/EXT1/EXTL2/DSEL/HS6ST1/CHPF/HS3ST4/HEXB/GAL3ST4/CHST13/XYLT1/PPARD/B4GALT7	30
BP	GO:0006283	transcription-coupled nucleotide-excision repair	24/4749	73/18670	0.0944	0.3167	0.2576	UBB/RFC2/RPS27A/CDK7/UBA52/ERCC8/POLD4/POLR2I/ERCC5/ERCC2/GTF2H2/POLR2C/GTF2H1/ZNF830/XRCC1/PRPF19/MNAT1/POLR2J/GTF2H5/XPA/COPS7A/CUL4A/POLR2A/ERCC1	24
BP	GO:0031100	animal organ regeneration	24/4749	73/18670	0.0944	0.3167	0.2576	NOTCH1/CDK1/CDKN1A/NR4A3/PPARG/SULF2/AURKA/IL10/CCNA2/PTCH1/TYMS/HMOX1/PKM/AXL/FLT3/EZH2/VTN/BAK1/CEBPB/ADM/TGFB1/CCND1/PDX1/LPIN1	24
BP	GO:0044766	multi-organism transport	24/4749	73/18670	0.0944	0.3167	0.2576	IFIT1/SEC13/KPNA2/NUP98/BST2/UBB/NUP153/RPS27A/UBA52/NUP88/THOC3/FMR1/KPNA3/POM121C/NUP205/RAE1/NUP50/RAB40B/NUP93/NUP35/AAAS/NUP62/SEH1L/TRIM15	24
BP	GO:1902579	multi-organism localization	24/4749	73/18670	0.0944	0.3167	0.2576	IFIT1/SEC13/KPNA2/NUP98/BST2/UBB/NUP153/RPS27A/UBA52/NUP88/THOC3/FMR1/KPNA3/POM121C/NUP205/RAE1/NUP50/RAB40B/NUP93/NUP35/AAAS/NUP62/SEH1L/TRIM15	24
BP	GO:0032479	regulation of type I interferon production	39/4749	126/18670	0.09457	0.3167	0.2576	IRF7/RELB/IL10/ISG15/TLR8/TREX1/SIRPA/TIRAP/HMGB1/NFKB2/PQBP1/IRF5/TLR4/TRIM25/MMP12/TRAIP/HAVCR2/UBA7/XRCC6/NPLOC4/POLR3H/CYLD/TLR2/FLOT1/DTX4/IRAK1/DHX33/RNF216/NLRC3/IRF3/IFI16/RIPK2/DDX41/PTPRS/CRCP/STAT1/POLR3GL/ZCCHC3/TRIM15	39
BP	GO:0000132	establishment of mitotic spindle orientation	11/4749	29/18670	0.09461	0.3167	0.2576	SAPCD2/CENPA/GPSM2/PLK1/NUMA1/NDC80/ARHGEF2/HTT/ACTR1A/NSFL1C/MCPH1	11
BP	GO:0010390	histone monoubiquitination	11/4749	29/18670	0.09461	0.3167	0.2576	UHRF1/DDB2/RYBP/DTX3L/BCOR/RNF40/PCGF6/PCGF1/PCGF5/BMI1/RNF168	11
BP	GO:0010954	positive regulation of protein processing	11/4749	29/18670	0.09461	0.3167	0.2576	IL1B/ENO1/GSN/TIMM17A/ASTL/SRC/SPON1/KLKB1/BAG2/MYH9/C6	11
BP	GO:0030970	retrograde protein transport, ER to cytosol	11/4749	29/18670	0.09461	0.3167	0.2576	DERL1/SYVN1/VCP/HERPUD1/NPLOC4/UBE2G2/BCAP31/SEC61B/EDEM2/BRSK2/UBAC2	11
BP	GO:0044788	modulation by host of viral process	11/4749	29/18670	0.09461	0.3167	0.2576	CSF1R/ANXA2P2/SMC3/ANXA2/TBC1D20/CFL1/FMR1/CCNK/ZC3H12A/STOM/NUCKS1	11
BP	GO:1902624	positive regulation of neutrophil migration	11/4749	29/18670	0.09461	0.3167	0.2576	IL1R1/RAC1/TIRAP/DAPK2/CD74/C3AR1/RAC2/CD99L2/C1QBP/THBS4/IL23A	11
BP	GO:1903513	endoplasmic reticulum to cytosol transport	11/4749	29/18670	0.09461	0.3167	0.2576	DERL1/SYVN1/VCP/HERPUD1/NPLOC4/UBE2G2/BCAP31/SEC61B/EDEM2/BRSK2/UBAC2	11
BP	GO:2000515	negative regulation of CD4-positive, alpha-beta T cell activation	11/4749	29/18670	0.09461	0.3167	0.2576	BCL6/CBFB/TNFSF4/LGALS9/HMGB1/FOXP3/IL4R/SMAD7/HLX/ZC3H12A/JAK3	11
BP	GO:0002690	positive regulation of leukocyte chemotaxis	28/4749	87/18670	0.09468	0.3167	0.2577	CXCL13/VEGFA/WNK1/RAC1/TIRAP/CCR1/DAPK2/LGALS9/HMGB1/CSF1/CXCL10/SERPINE1/SWAP70/CCR6/CCR2/CCL3/CD74/AIF1/FPR2/C3AR1/RAC2/RARRES2/C1QBP/CCL7/THBS4/CCL27/VEGFC/IL23A	28
BP	GO:0002448	mast cell mediated immunity	17/4749	49/18670	0.09515	0.3176	0.2584	NR4A3/FES/LGALS9/S100A13/GAB2/MILR1/IL4R/HMOX1/BTK/LAT/SNAP23/UNC13D/RAC2/RABGEF1/IL13/FER/SPHK2	17
BP	GO:0008347	glial cell migration	17/4749	49/18670	0.09515	0.3176	0.2584	MBOAT7/CDK5/CSF1/SRGAP2/TSPO/CCR2/TIAM1/CCL3/SUN2/CCL2/SCRIB/LRP1/NDN/P2RY1/HEXB/SYNE2/CX3CR1	17
BP	GO:0097300	programmed necrotic cell death	17/4749	49/18670	0.09515	0.3176	0.2584	PPIF/TNF/TLR4/BAX/RIPK3/ARHGEF2/CFLAR/FAS/MAP3K5/CYLD/IRF3/BIRC3/TRAF2/FZD9/SLC25A4/SPATA2/PGAM5	17
BP	GO:1990090	cellular response to nerve growth factor stimulus	17/4749	49/18670	0.09515	0.3176	0.2584	NTRK2/NTRK1/HSPA5/E2F1/NTRK3/KAT2A/RPS3/MICALL1/CORO1A/RAPGEF1/UBE3A/CRK/RAPGEF2/CDC5L/ARF6/NTF3/ID1	17
BP	GO:0048863	stem cell differentiation	75/4749	257/18670	0.09528	0.3179	0.2586	TWIST1/LIF/NOTCH1/TP73/BATF/SRF/CBFB/CORO1C/TP63/SEMA4C/ASCL1/SEMA7A/STAT3/MSX1/SEMA3G/SHC4/ALX1/HSPA9/PSMD8/SEMA6C/PSMD1/PSMD2/MSI2/SETD6/RBPJ/SEMA6B/EFNB1/PSMF1/CYP26C1/RUNX2/ZFP36L2/JAG1/FAM172A/PTPRC/CFL1/A2M/PSMD9/PSMA5/OSM/NOLC1/ZNF281/WNT7A/SOX8/PSMB7/ERCC2/PSMD5/SOX11/SEMA3B/YAP1/SEMA5B/PSME2/SFRP1/PSMB5/ESR1/LRP6/PSMB4/SEMA4D/PSMA3/LBH/PSMD10/KDM4C/SEMA5A/PSMB1/PSMD7/PSMB3/OCIAD1/MAPK1/RDH10/PEF1/LAMA5/PSMC5/LDB1/GATA3/PDX1/PSMD11	75
BP	GO:0031346	positive regulation of cell projection organization	109/4749	383/18670	0.09558	0.3187	0.2593	CDC42EP4/SKIL/ANLN/VEGFA/FSCN1/ITGA2/MAP6/ITGA3/NTRK2/FES/NTRK1/SRF/RAC1/PLXNB2/GRN/CYFIP1/CNTF/CAMK1/CORO1C/KCTD17/PLXNB1/TNFRSF12A/HSPA5/CREB3L2/LRP8/SEMA7A/CENPJ/MTOR/CUX1/ZFYVE27/CDC42EP1/SRC/TENM1/SCN1B/TIAM1/SYT4/CFLAR/CORO1B/AMIGO1/NTRK3/ATMIN/DVL3/PLXNA1/TGFB3/PAK1/PTK7/KAT2A/CPNE5/CRTC1/HTT/ARHGAP35/CBFA2T2/PTK6/PAK3/FBXO31/SMURF1/EPS8L2/TMEM106B/PRKCI/TWF2/L1CAM/PLXND1/ITGA6/EZH2/SCARF1/DVL1/ZMYND10/LRP1/ARAP1/RALA/TMEM30A/LIMK1/PLEKHM1/STYXL1/CNR1/GPC2/RAPGEF1/STK25/FMR1/MARK4/RAC2/IST1/RASAL1/RAPGEF2/WRAP73/NEGR1/DLG5/PARP6/LTK/PACSIN1/SEMA4D/ARHGDIA/APC/LLPH/NEFL/WASF2/RUFY3/BCAS3/C15orf62/SEMA5A/CDC42/ADNP/TRPC5/GDI1/P2RX7/FYN/NME2/DLG4/ILK	109
BP	GO:0007018	microtubule-based movement	82/4749	283/18670	0.09653	0.3209	0.2611	KIF20A/KIF2C/KIF14/KIFC1/KIF4A/KIF15/KIF23/KIF24/KIF20B/DLGAP5/KIF1C/RACGAP1/BBS2/KIF18A/SFPQ/TTC30A/KIF11/UXT/KLC1/WDR34/BLOC1S6/CENPE/DYNLRB1/BLOC1S1/KIF4B/UBB/ICK/CNIH2/KLC3/SUN2/HTT/FYCO1/BLOC1S4/CCDC114/DNHD1/IFT122/AP3D1/TEKT5/MKKS/IFT172/TTC21A/DTNBP1/TTLL1/KIF3C/FMR1/IFT27/MAP1S/WDR60/BBS12/WDR19/BAG3/AP3M2/SNAPIN/DNAI2/LAMP1/IFT80/LRPPRC/ACTR1A/RHOT2/MAP1A/TEKT2/RAB1A/NEFL/ARL3/TMEM201/TTC26/AP3B2/COPG2/CDC42/CLUAP1/STARD9/UCHL1/SPG7/SYNE2/KIF19/WDR66/TNPO1/SYBU/KIFC2/DNAH6/MGARP/TERF2	82
BP	GO:0010977	negative regulation of neuron projection development	47/4749	155/18670	0.09668	0.3209	0.2611	CRMP1/BCL11A/YWHAH/CDK5/SPP1/GORASP1/SEMA4C/SEMA7A/PLK2/RGMA/SEMA3G/SEMA6C/ADCY6/MYLIP/SEMA6B/PTPN9/LGALS1/CBFA2T2/STX1B/LRP4/CARM1/FGF13/TBX6/ARHGAP4/LRP1/THY1/UBE3A/CTSZ/SEMA3B/VIM/SEMA5B/PMP22/GSK3A/RAPGEF2/SNAPIN/RAP1GAP2/PTPRS/ITM2C/SEMA4D/ARF6/ARHGDIA/ID1/RUFY3/SEMA5A/RTN4R/TRPC5/GDI1	47
BP	GO:0030049	muscle filament sliding	14/4749	39/18670	0.09669	0.3209	0.2611	MYLK2/MYL6/MYL1/TPM2/MYBPC3/MYH7/TNNC1/MYH4/VIM/MYL6B/TPM1/MYH6/TCAP/MYBPC2	14
BP	GO:0030204	chondroitin sulfate metabolic process	14/4749	39/18670	0.09669	0.3209	0.2611	CHST15/CHPF2/IDS/CSGALNACT1/IDUA/SLC35D1/B3GALT6/SPOCK3/CHST7/DSEL/CHPF/HEXB/CHST13/XYLT1	14
BP	GO:0033275	actin-myosin filament sliding	14/4749	39/18670	0.09669	0.3209	0.2611	MYLK2/MYL6/MYL1/TPM2/MYBPC3/MYH7/TNNC1/MYH4/VIM/MYL6B/TPM1/MYH6/TCAP/MYBPC2	14
BP	GO:0038179	neurotrophin signaling pathway	14/4749	39/18670	0.09669	0.3209	0.2611	NTRK2/NTRK1/CYFIP1/ZFYVE27/CYFIP2/SRC/NTRK3/CORO1A/DDIT4/RAPGEF1/NDN/RAPGEF2/NTF3/SLC9A6	14
BP	GO:0042769	DNA damage response, detection of DNA damage	14/4749	39/18670	0.09669	0.3209	0.2611	DTL/TREX1/DNAJA1/UBE2B/MRPS11/UBB/RPS3/RFC2/RPS27A/UBA52/POLD4/NEK1/WDR48/CUL4A	14
BP	GO:0045684	positive regulation of epidermis development	14/4749	39/18670	0.09669	0.3209	0.2611	VDR/NOTCH1/HPSE/PTCH1/TNF/WNT10B/NUMA1/SFN/SFRP4/CYP27B1/IL20/PPARD/TRIM16/NME2	14
BP	GO:0045911	positive regulation of DNA recombination	14/4749	39/18670	0.09669	0.3209	0.2611	TNFSF4/TFRC/UBE2B/TP53BP1/PTPRC/TIMELESS/ERCC2/WRAP53/TNFSF13/IL4/MAD2L2/WRN/TGFB1/WAS	14
BP	GO:0032868	response to insulin	79/4749	272/18670	0.09697	0.3217	0.2617	EGR1/EGR2/IL1B/RAB31/PPARG/ICAM1/SH2B2/IL10/CYFIP1/ATP6V0D1/MZB1/CEACAM1/SOCS2/EIF4EBP1/SYAP1/SLC2A8/PTPN1/ATP6V0B/MTOR/ESRRA/SORL1/MYO5A/SRC/SOCS3/PKM/GGH/CFLAR/RAB13/SRSF4/ATP6V1E1/IGF1R/CRY1/PAK1/ENHO/FFAR3/SLC2A4/ATP6V0C/FOXO1/PHIP/UPRT/PRKCI/ATP6V1A/TLR2/SP1/ADIPOR1/SLA2/GNAI2/INSRR/EPM2AIP1/ACVR1C/APRT/GSK3A/RARRES2/ATP6V1G1/BGLAP/ADM/ADIPOQ/GPR21/TNFSF10/FER/AANAT/ZFP36L1/GCLC/CPEB1/PRKCB/INSR/MAX/APC/HDAC9/STAT1/ATP6V1E2/NUCKS1/SESN2/SHC1/GKAP1/LPIN1/TRIB3/USO1/SIRT1	79
BP	GO:0046474	glycerophospholipid biosynthetic process	64/4749	217/18670	0.09783	0.324	0.2636	PTPN13/PDGFA/CPNE7/SBF1/PCTP/MFSD2A/MTMR3/AGPAT3/AGPAT2/PLEKHA1/DGKZ/INPP4A/FABP5/PLA2G12A/HTR2A/PIGK/LPCAT2/SH3YL1/PIGH/PIK3R5/PITPNM1/PIKFYVE/DPM2/MTMR9/PLEKHA2/PIP5K1B/ACP6/PIGQ/PI4K2A/PIGO/STARD10/FPR2/PLEKHA8/AGAP2/LPCAT4/PIGC/RAB38/PTPMT1/MTMR14/PIGW/PIK3C3/PLA2G2A/TAMM41/LCLAT1/PIP4K2A/PIK3R4/PIGM/PTDSS1/PIGA/AGK/PIP4K2B/PLA2G5/ATM/TAZ/PIP5K1A/GPAT2/PLEKHA3/PDGFB/PIGG/LPIN1/PIGT/CRLS1/PGS1/SLC44A1	64
BP	GO:0002244	hematopoietic progenitor cell differentiation	50/4749	166/18670	0.0979	0.324	0.2636	ANLN/NOTCH1/TP73/TOP2A/CSF1R/BATF/SRF/PTPN6/ESCO2/SPI1/TREX1/CBFB/PLD4/HSPA9/PSMD8/PSMD1/PSMD2/SSBP3/STON2/PSMF1/FLT3/ZNF784/PTPRC/ACP6/PSMD9/PSMA5/OSM/TNFRSF13B/RBM47/PSMB7/ERCC2/PSMD5/YAP1/PSME2/DACT2/SFRP1/HERC6/PSMB5/PYGO1/PSMB4/PSMA3/PSMD10/TGFB1/PSMB1/PSMD7/PSMB3/PSMC5/LDB1/GATA3/PSMD11	50
BP	GO:0000768	syncytium formation by plasma membrane fusion	19/4749	56/18670	0.09791	0.324	0.2636	CD109/ADAM12/CAMK1/CD9/PTGFRN/CXCL10/SBNO2/IL4R/CFLAR/MYOF/CXCL9/FLOT1/TANC1/MYH9/TYROBP/FER1L5/ADAM9/TCTA/GCM1	19
BP	GO:0034508	centromere complex assembly	19/4749	56/18670	0.09791	0.324	0.2636	CENPF/CENPA/HJURP/CENPM/CENPW/NASP/CENPE/CENPT/CENPO/CENPI/CENPP/CENPN/HELLS/OIP5/CENPV/SENP6/POGZ/TRAPPC12/CENPK	19
BP	GO:0140253	cell-cell fusion	19/4749	56/18670	0.09791	0.324	0.2636	CD109/ADAM12/CAMK1/CD9/PTGFRN/CXCL10/SBNO2/IL4R/CFLAR/MYOF/CXCL9/FLOT1/TANC1/MYH9/TYROBP/FER1L5/ADAM9/TCTA/GCM1	19
BP	GO:0008033	tRNA processing	40/4749	130/18670	0.09848	0.3257	0.265	TSEN2/QTRT1/TRMT12/FAM98B/CTU1/GTPBP3/TSEN15/ALKBH8/TRMT1/POP5/OSGEPL1/ELP5/TARBP1/PUS1/NSUN6/TRMT10B/TSEN34/ELAC1/SEPHS1/TRMT13/TRPT1/TYW1B/TRIT1/ELP4/TRMT112/PUSL1/METTL8/DUS1L/KTI12/MTFMT/CPSF1/TRMT10C/C9orf64/RPP30/TRMT1L/THG1L/NSUN2/TRNT1/CDKAL1/PUS10	40
BP	GO:0051494	negative regulation of cytoskeleton organization	45/4749	148/18670	0.09858	0.3259	0.2651	CCNF/NEK2/CAPZB/GSN/CKAP2/MYADM/SWAP70/TMOD2/CAPG/ARHGEF2/CLIP3/CORO1B/ADD3/KAT2A/PFN2/HIP1R/NUBP1/S1PR1/MDM1/PICK1/TMSB4Y/SPTBN1/FGF13/CORO1A/STMN1/CLASP2/TRIOBP/TWF2/SPTAN1/MKKS/ARAP1/MID1/CAPZA1/TUBB4A/TRIM54/KANK3/TMSB15A/VILL/TMEM67/CHMP2A/APC/WASF2/WAS/CDH5/ADD2	45
BP	GO:0046364	monosaccharide biosynthetic process	31/4749	98/18670	0.09938	0.3283	0.2671	TPI1/GAPDH/CHST15/ENO1/PGAM1/ATF3/GPI/SLC25A1/SDS/CRTC2/ALDOC/CRY1/KAT2A/ATF4/PER2/FOXO1/MDH2/ENO3/MAEA/C1QTNF3/ALDOA/GNMT/ADIPOQ/DGAT2/SLC35B4/ALDOB/PGD/CLK2/SESN2/AKR1A1/SIRT1	31
BP	GO:0007062	sister chromatid cohesion	21/4749	63/18670	0.09961	0.3289	0.2676	ESPL1/CDCA5/BUB1B/CDC20/ESCO2/BUB1/SFPQ/PPP2R1A/SMC3/PLK1/FEN1/BOD1/DSCC1/CHTF8/REC8/STAG3/DDX11/SMC1A/AXIN2/POGZ/SMC5	21
BP	GO:0006516	glycoprotein catabolic process	10/4749	26/18670	0.09985	0.3289	0.2676	NEU4/HPSE/GPC1/MMP12/CST3/FBXO27/EDEM2/ADAMTS9/MANBA/FBXO44	10
BP	GO:0042481	regulation of odontogenesis	10/4749	26/18670	0.09985	0.3289	0.2676	CSF1/MSX1/BCOR/RUNX2/AMTN/TNFRSF11B/CD34/FGF8/TGFB1/AMELX	10
BP	GO:0051125	regulation of actin nucleation	10/4749	26/18670	0.09985	0.3289	0.2676	CYFIP1/GSN/CORO1B/HIP1R/PICK1/CORO1A/WHAMM/AP1AR/WAS/FMN1	10
BP	GO:0060669	embryonic placenta morphogenesis	10/4749	26/18670	0.09985	0.3289	0.2676	IL10/ST14/SOCS3/SPINT1/DNAJB6/ADM/RSPO3/ZFP36L1/FZD5/GCM1	10
BP	GO:1900120	regulation of receptor binding	10/4749	26/18670	0.09985	0.3289	0.2676	PTPRF/IL10/PHLDA2/ANXA2P2/MMP9/ANXA2/GREM2/PLCL2/ADAM15/ADIPOQ	10
BP	GO:1901992	positive regulation of mitotic cell cycle phase transition	29/4749	91/18670	0.1002	0.3296	0.2681	ESPL1/CDCA5/UBE2C/CDK1/CDT1/DTL/HSPA2/DLGAP5/CDC25A/CDC6/CDC25C/WNT10B/CCNB1/FBXO5/DBF4B/CDC45/AIF1/BRD4/CDK10/ANAPC11/PBX1/MTA3/ADAMTS1/ANKRD17/PLCB1/TGFB1/CUL4A/CDC25B/CCND1	29
BP	GO:0030178	negative regulation of Wnt signaling pathway	62/4749	210/18670	0.1002	0.3296	0.2681	EGR1/NOTCH1/IGFBP4/TLE4/TLE2/NKD1/CTHRC1/LIMD1/PSMD8/DVL3/SFRP4/TMEM170B/PSMD1/PSMD2/FZD6/WWTR1/FGF9/PSMF1/PFDN5/FOXO1/LRP4/TCF7L2/NXN/CYLD/STK3/TLE3/DVL1/PSMD9/LRP1/PSMA5/DDIT3/HMGXB4/WWOX/RAPGEF1/EMD/RNF213/PSMB7/INVS/PSMD5/SIAH2/GSK3A/PSME2/SFRP1/IFT80/PSMB5/MLLT3/BICC1/MAD2L2/LRP6/PSMB4/PSMA3/APC/AXIN2/PSMD10/TMEM64/PSMB1/PSMD7/PSMB3/PSMC5/IGFBP6/TRABD2B/PSMD11	62
BP	GO:0001738	morphogenesis of a polarized epithelium	43/4749	141/18670	0.1005	0.3304	0.2688	SAPCD2/RAC1/VANGL1/TP63/NKD1/TIAM1/CTHRC1/PSMD8/DVL3/PSMD1/PSMD2/FZD6/PTK7/PSMF1/SMURF1/DVL1/PSMD9/AP2S1/PSMA5/WNT7A/PSMB7/PSMD5/WDR1/PSME2/BRSK2/DLG5/SFRP1/RSPO3/PSMB5/MLLT3/PSMB4/PSMA3/MED12/PARD6A/FZD5/PSMD10/CDC42/PSMB1/PSMD7/PSMB3/LAMA5/PSMC5/PSMD11	43
BP	GO:0033077	T cell differentiation in thymus	23/4749	70/18670	0.1005	0.3304	0.2688	EGR3/JAG2/SRF/FOXP3/CCR6/RIPK3/RPS6/CD74/ZFP36L2/DNAJA3/PTPRC/FZD8/ERBB2/IL7R/CD3E/CARD11/NCAPH2/ZFP36L1/VNN1/FZD5/RAG2/ZAP70/GATA3	23
BP	GO:0006368	transcription elongation from RNA polymerase II promoter	27/4749	84/18670	0.1007	0.3307	0.269	IWS1/ENY2/CDK7/CCNT2/BRD4/EZH2/SUPT6H/RECQL5/RNF8/POLR2I/ERCC2/CCNK/ELP4/GTF2H2/POLR2C/GTF2H1/EAF1/MLLT3/MNAT1/ELL/POLR2J/EAF2/GTF2H5/NCBP2/POLR2A/EAPP/RNF168	27
BP	GO:0070371	ERK1 and ERK2 cascade	91/4749	317/18670	0.1007	0.3308	0.2691	IQGAP3/LIF/IL1B/NOTCH1/FAM83D/ICAM1/DUSP10/DUSP4/CSF1R/CCL20/NTRK1/KLF4/PDGFA/CCL3L3/PTPN6/EPHB1/DUSP6/CTSH/SIRPA/CCL22/TIRAP/CCR1/GPNMB/CEACAM1/LGALS9/ATF3/HMGB1/TNF/SEMA7A/TLR4/CHRNA10/BTN2A2/PTPN1/TRAF7/SRC/TIAM1/CFLAR/SCIMP/ARRB1/HTR2A/CCL3/PTGER4/HAVCR2/CD74/FLT3/CCL2/SYNJ2BP/ZFP36L2/CCL17/CASR/PTPRC/EZR/PRKCA/CCL18/NOD2/LRP1/NDRG2/IL26/FLT1/SIRT3/GNAI2/RAPGEF1/FPR2/JUN/ERBB2/CD44/C3orf33/FLT4/RAPGEF2/BRAF/ADIPOQ/GLIPR2/PLA2G2A/RIPK2/F2R/ZFP36L1/TIMP3/P2RY1/CCL23/FGF8/TNFAIP8L3/TNFSF11/CCL7/PLA2G5/DDT/TGFB1/CCL15/MAPK1/PDGFB/SHC1/DUSP1	91
BP	GO:0050727	regulation of inflammatory response	136/4749	485/18670	0.1008	0.3309	0.2692	IL1B/PBK/IL18/TYRO3/IL21/PPARG/ITGA2/NLRP3/DUSP10/ADORA2A/ABCC1/IL10/IL1R1/ACP5/KLF4/CCL3L3/HCK/TTBK1/BCL6/IL17A/TREX1/GRN/C2CD4B/ZYX/PTGIS/SIRPA/TNFSF4/CLEC7A/MMP9/TNF/SEMA7A/PROS1/IL2RA/CD200/TLR4/PROC/SERPINE1/FOXP3/LDLR/SBNO2/GPX1/ABCD1/IL1R2/FFAR2/PDCD4/CCR2/SOCS3/C1QB/ABCD2/GGT1/TGM2/BTK/CCL3/CLU/PTGER4/SETD6/BAP1/FFAR3/C5orf30/CFHR4/PTPRC/RPS19/CYLD/HLA-E/CD47/BRD4/CCL18/TLR2/A2M/VTN/NOD2/GBA/OSM/CD19/SHPK/LTA/GPX4/CNR1/C1QTNF3/TLR6/CD46/RHBDD3/FPR2/PARK7/C3AR1/CR2/SUSD4/IL17RC/NFKBIA/DEFB114/CEBPB/IDO1/CFI/NLRC3/IRF3/ZC3H12A/KLKB1/NEAT1/RABGEF1/LILRA5/BIRC3/SERPING1/IL20/CFB/MMP26/GHRL/CHID1/CFHR1/S100A8/ADIPOQ/IL4/PLA2G2A/ESR1/TNFRSF1B/C1QA/C1R/CD6/MGST2/NT5E/PSMB4/C1QBP/NUPR1/SIGLEC10/C6/BCR/TNFSF11/MCPH1/ATM/PPARD/DDT/METRNL/SPATA2/CDH5/C2CD4A/GATA3/IL23A	136
BP	GO:0099643	signal release from synapse	51/4749	170/18670	0.101	0.3312	0.2695	ADORA2A/PPFIA4/RIMS3/CDK5/SYN1/NCS1/CHRNA5/STX11/HCRT/BLOC1S6/P2RX1/SYT4/SNAP47/HTR2A/CAMK2A/PPT1/SNAP29/PFN2/APBA2/STX1B/DVL1/SCRIB/STX19/DRD1/SNAP23/DTNBP1/WNT7A/PPFIA3/CNR1/FMR1/SYT11/TACR2/ERC2/SNAPIN/NAPB/MCTP2/KCNC4/STX2/RPH3A/DOC2B/CHRNA3/PRKCB/P2RY1/SYN2/CACNB2/FBXL20/LIN7C/SV2A/PDZD11/P2RX7/TRIM9	51
BP	GO:0030490	maturation of SSU-rRNA	16/4749	46/18670	0.1014	0.3321	0.2701	RPS8/MRPS11/BYSL/RPS19/FAM207A/RIOK1/RPS16/NOP14/UTP20/UTP23/BTRC/ABT1/RPS28/RCL1/UTP3/NGDN	16
BP	GO:0044003	modification by symbiont of host morphology or physiology	16/4749	46/18670	0.1014	0.3321	0.2701	GAPDH/TYMS/KPNA2/NTRK3/SCRIB/RXRA/KPNA3/CCNK/BCL2L1/ZC3H12A/DEFA1B/KRT6A/INSR/ATG7/TGFB1/BAD	16
BP	GO:0071675	regulation of mononuclear cell migration	16/4749	46/18670	0.1014	0.3321	0.2701	CCR1/LGALS3/HMGB1/TNF/CSF1/CXCL10/SERPINE1/CCR2/AIF1/FPR2/C3AR1/RARRES2/PLCB1/TGFB1/CCL27/DUSP1	16
BP	GO:0030278	regulation of ossification	60/4749	203/18670	0.1026	0.3357	0.2731	TWIST1/EGR2/NOTCH1/RASSF2/ISG15/CCR1/BMP2K/TP63/PTCH1/TNF/CSF1/SKI/ESRRA/WNT10B/CLIC1/NBR1/FBXO5/CTHRC1/LIMD1/GNAS/CCL3/PTGER4/TGFB3/RBPJ/FAM20C/SMAD6/BCOR/RUNX2/S1PR1/PDLIM7/JAG1/SMURF1/LRP4/ATRAID/TRPM4/IFITM1/CYP27B1/TOB2/ACVR2B/CEBPB/SOX11/SRGN/TPH1/BGLAP/SMAD1/SFRP1/SUCO/FZD9/SEMA4D/TXLNG/AXIN2/TMEM119/PBX1/ID1/TGFB1/TMEM64/MAPK1/DHRS3/P2RX7/ILK	60
BP	GO:0010742	macrophage derived foam cell differentiation	13/4749	36/18670	0.1028	0.3358	0.2732	IL18/CSF2/PPARG/ABCG1/CSF1/ABCA1/NFKBIA/ABCA5/ADIPOQ/PLA2G2A/CETP/STAT1/TGFB1	13
BP	GO:0032205	negative regulation of telomere maintenance	13/4749	36/18670	0.1028	0.3358	0.2732	SRC/PIF1/TERF1/TNKS2/ACD/CTC1/POT1/XRCC1/SMG6/TINF2/ATM/ERCC1/TERF2	13
BP	GO:0051031	tRNA transport	13/4749	36/18670	0.1028	0.3358	0.2732	SEC13/NUP98/NUP153/NUP88/POM121C/NUP205/RAE1/NUP50/NUP93/NUP35/AAAS/NUP62/SEH1L	13
BP	GO:0090077	foam cell differentiation	13/4749	36/18670	0.1028	0.3358	0.2732	IL18/CSF2/PPARG/ABCG1/CSF1/ABCA1/NFKBIA/ABCA5/ADIPOQ/PLA2G2A/CETP/STAT1/TGFB1	13
BP	GO:2001171	positive regulation of ATP biosynthetic process	13/4749	36/18670	0.1028	0.3358	0.2732	PFKFB3/ENO1/ENTPD5/STAT3/VCP/HTR2A/PFKFB4/PINK1/PFKFB2/IL4/INSR/TAZ/P2RX7	13
BP	GO:0031214	biomineral tissue development	49/4749	163/18670	0.1032	0.3367	0.2739	TWIST1/NOTCH1/ISG15/CCR1/ANXA2P2/GPNMB/BMP2K/SPP1/ANXA2/SBNO2/WNT10B/NBR1/FBXO5/CCL3/TGFB3/PTHLH/ATF4/PHEX/FAM20C/ZBTB40/BCOR/S1PR1/FOXO1/CNNM4/ATRAID/TRPM4/TFIP11/AMTN/SBDS/CYP27B1/ERCC2/ACVR2B/CEBPB/SRGN/KLF10/HTN3/BGLAP/EIF2AK3/FZD9/TXLNG/FBXL15/AXIN2/TMEM119/CER1/AMELY/TGFB1/CEMP1/AMELX/P2RX7	49
BP	GO:0071426	ribonucleoprotein complex export from nucleus	39/4749	127/18670	0.1042	0.3398	0.2764	SEC13/U2AF1/NUP98/SMG5/POLDIP3/IWS1/RNPS1/RPS15/ENY2/SRSF4/NUP153/UPF1/MAGOHB/ABCE1/ALKBH5/SUPT6H/NUP88/THOC3/U2AF1L4/POM121C/NUP205/RAE1/NUP50/DHX38/SDAD1/MAGOH/CPSF1/SMG6/GLE1/NUP93/DDX19A/CDC40/NUP35/AAAS/NCBP2/NUP62/SEH1L/YTHDC1/NXF3	39
BP	GO:0007131	reciprocal meiotic recombination	18/4749	53/18670	0.1044	0.34	0.2766	TOP2A/TRIP13/RAD54L/SYCE3/UBE2B/RAD51/DMC1/MND1/HELQ/REC8/EME1/KLHDC3/UBR2/ANKRD31/ATM/MLH3/RNF212/RAD54B	18
BP	GO:0045840	positive regulation of mitotic nuclear division	18/4749	53/18670	0.1044	0.34	0.2766	ESPL1/IL1B/CDCA5/UBE2C/CDT1/AURKA/DLGAP5/NUSAP1/NUMA1/PHIP/ANAPC11/NSFL1C/INSR/FGF8/SMC5/TGFB1/PDGFB/NUP62	18
BP	GO:0050704	regulation of interleukin-1 secretion	18/4749	53/18670	0.1044	0.34	0.2766	NLRP3/TLR8/HK1/LGALS9/PML/HMGB1/TLR4/LILRA2/IL1R2/CCL3/NOD2/ZC3H12A/LILRA5/RIPK2/CARD8/FZD5/TRIM16/P2RX7	18
BP	GO:0001763	morphogenesis of a branching structure	58/4749	196/18670	0.105	0.341	0.2774	VDR/VEGFA/NOTCH1/IL10/SRF/PDGFA/BCL11A/CTSH/TP63/PRDM1/PTCH1/PML/ST14/TNF/CSF1/SIRT6/DCHS1/SRC/SOCS3/ETV5/NKX2-1/TGM2/PLXNA1/PAK1/PKD2/SPINT1/HOXB7/CASR/KDM5B/PLXND1/GREB1L/TIMELESS/FEM1B/RXRA/SOX8/GDF7/CTSZ/LRP5L/YAP1/NRARP/DDR1/BTRC/DLG5/SFRP1/ADM/RSPO3/ESR1/LRP6/HOXA11/FGF8/PBX1/FZD5/TGFB1/RDH10/LAMA5/ESRP2/ILK/GCM1	58
BP	GO:0000715	nucleotide-excision repair, DNA damage recognition	9/4749	23/18670	0.1052	0.341	0.2774	DDB2/UBB/RPS27A/RAD23B/UBA52/CETN2/XPA/COPS7A/CUL4A	9
BP	GO:0009595	detection of biotic stimulus	9/4749	23/18670	0.1052	0.341	0.2774	NLRP3/TREX1/CLEC7A/TLR4/CD1D/PGLYRP3/TLR2/NOD2/TLR6	9
BP	GO:0042401	cellular biogenic amine biosynthetic process	9/4749	23/18670	0.1052	0.341	0.2774	SMOX/SMS/MOXD1/SAT1/OAZ3/OAZ2/TPH1/AANAT/OAZ1	9
BP	GO:0070193	synaptonemal complex organization	9/4749	23/18670	0.1052	0.341	0.2774	HSPA2/TRIP13/SYCE3/UBE2B/PLK1/REC8/STAG3/SYCE2/MLH3	9
BP	GO:0072215	regulation of metanephros development	9/4749	23/18670	0.1052	0.341	0.2774	EGR1/LIF/PDGFA/WWTR1/BASP1/YAP1/ADIPOQ/STAT1/PDGFB	9
BP	GO:0097150	neuronal stem cell population maintenance	9/4749	23/18670	0.1052	0.341	0.2774	NOTCH1/ASPM/FOXO1/JAG1/FANCC/SS18/MMP24/MCPH1/DLL1	9
BP	GO:1902254	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator	9/4749	23/18670	0.1052	0.341	0.2774	ZNF385A/RRM2B/CD74/TAF9B/MUC1/BDKRB2/BCL2L12/CD44/SIRT1	9
BP	GO:0099003	vesicle-mediated transport in synapse	61/4749	207/18670	0.1052	0.341	0.2774	ADORA2A/RIMS3/CDK5/SYN1/NCS1/CHRNA5/ACTG1/STX11/BLOC1S6/P2RX1/SYT4/SNAP47/HTR2A/BLOC1S1/CAMK2A/CNIH2/SNAP29/PFN2/STON2/SLC2A4/BLOC1S4/SH3GL1/APBA2/STX1B/PINK1/DVL1/AP3D1/SCRIB/STX19/DRD1/SNAP23/DTNBP1/RAB27A/WNT7A/PPFIA3/CNR1/FMR1/DNAJC6/SYT11/AP3M2/ERC2/SNAPIN/NAPB/NLGN4Y/DNM1/EEA1/STX2/CANX/DOC2B/PRKCB/PACSIN1/P2RY1/ARF6/CACNB2/FBXL20/KIAA1107/AP3B2/SV2A/P2RX7/TRIM9/ACTB	61
BP	GO:0016573	histone acetylation	47/4749	156/18670	0.1054	0.3415	0.2779	TWIST1/LIF/IL1B/GTF3C4/IRF4/SPI1/DPF3/BRCA2/PHF10/FOXP3/SMARCB1/CRTC2/ING3/NAP1L2/ING5/KANSL3/IWS1/ARRB1/MORF4L2/KANSL1L/KAT2A/ACTL6A/TAF1L/YEATS4/SUPT3H/TAF9B/MUC1/TAF6L/TAF10/CHEK1/MCRS1/BRPF3/TAF7/KAT6B/DPF1/TADA2A/SPHK2/CTBP1/TGFB1/ZNF451/TRIM16/LDB1/GATA3/CPA4/TADA1/KAT6A/SIRT1	47
BP	GO:0042100	B cell proliferation	30/4749	95/18670	0.1055	0.3417	0.278	IL21/CDKN1A/IL10/BCL6/TIRAP/TFRC/MZB1/TNFRSF4/TLR4/BAX/TNFRSF21/CTLA4/BTK/CD74/CD180/PTPRC/PLCL2/CD19/TNFRSF13B/MNDA/CR2/IL7R/IL7/IL13/CARD11/IL4/TYROBP/ATM/RAG2/SLC39A10	30
BP	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	37/4749	120/18670	0.106	0.343	0.279	SKIL/CD109/ITGA3/CDKN2B/LRG1/PMEPA1/SNX25/TGFB1I1/HSPA5/HSPA1A/SKI/DAND5/SMAD7/NKX2-1/SDCBP/UBB/TGFB3/PRDM16/SMAD6/RPS27A/SMURF1/FAM89B/UBA52/LEMD3/VASN/LDLRAD4/EID2/CITED2/SOX11/ZNF703/HTRA4/HTRA1/TGFB1/ZNF451/VEPH1/MIR17HG/SIRT1	37
BP	GO:0045576	mast cell activation	20/4749	60/18670	0.1062	0.3435	0.2795	NR4A3/FES/LGALS9/S100A13/GAB2/MILR1/IL4R/HMOX1/BTK/CD300LF/NDRG1/LAT/SNAP23/CNR1/UNC13D/RAC2/RABGEF1/IL13/FER/SPHK2	20
BP	GO:0045921	positive regulation of exocytosis	28/4749	88/18670	0.1064	0.344	0.2799	SDC4/CDK5/NCS1/GAB2/HYAL3/IL4R/SNF8/SYT4/SDCBP/ATP13A2/STAM/CD177/RAB3D/STXBP5/SDC1/CLASP2/HGS/RAB27A/CNR1/UNC13D/IL13/LAMP1/DOC2B/CHMP2A/RAB15/SPHK2/CACNB2/PTAFR	28
BP	GO:1904035	regulation of epithelial cell apoptotic process	28/4749	88/18670	0.1064	0.344	0.2799	ICAM1/TNF/ZFP36/GSN/ECSCR/SERPINE1/COL18A1/MTOR/PDCD4/HMOX1/HLA-G/CFLAR/PAK4/SFRP4/CCL2/TCF7L2/PRKCI/IL13/PIAS4/IL4/KRIT1/ZFP36L1/NUPR1/CD248/SEMA5A/GATA3/PDX1/BAD	28
BP	GO:0071559	response to transforming growth factor beta	74/4749	255/18670	0.1066	0.3445	0.2802	SKIL/FURIN/CD109/ITGA3/CDKN2B/LRG1/PMEPA1/ZYX/SNX25/TGFB1I1/PML/HSPA5/ARHGEF18/HSPA1A/SKI/USP9X/DAND5/NR3C1/SMAD7/SRC/NKX2-1/CFLAR/SDCBP/UBB/TGFB3/LIMS1/ZFYVE9/ZFHX3/PRDM16/PDCD5/SMAD6/STK16/RPS27A/ZFP36L2/SMURF1/FAM89B/UBA52/DUSP22/LEMD3/ARG1/VASN/WWOX/WNT7A/LDLRAD4/JUN/EPB41L5/ACVR1C/ACVR2B/TAB1/CRK/EID2/CITED2/SOX11/ZNF703/HTRA4/SMAD1/SFRP1/LEFTY1/ZFP36L1/HPGD/PARD6A/FOS/HTRA1/ID1/TGFB1/ZNF451/ADAM9/CDH5/VEPH1/MIR17HG/CX3CR1/LRRC32/FYN/SIRT1	74
BP	GO:0032204	regulation of telomere maintenance	26/4749	81/18670	0.1071	0.3457	0.2812	AURKB/NEK2/PML/SIRT6/SMG5/SRC/PIF1/UPF1/CCT5/TERF1/TNKS2/ACD/CTC1/GNL3/POT1/XRCC1/YLPM1/SMG6/ATR/TINF2/ATM/MAPK1/ERCC1/FBXO4/TERF2/CCT3	26
BP	GO:0030100	regulation of endocytosis	81/4749	281/18670	0.1075	0.3469	0.2822	IL1B/VEGFA/RAB31/PPARG/ITGA2/HCK/RAC1/SIRPA/CLEC7A/ANXA2P2/LGALS3/HIP1/HMGB1/TNF/PTPN1/SERPINE1/ANXA2/IL2RB/SRC/MERTK/SYT4/CLIP3/ARRB1/IL2RG/SDCBP/CLU/AXL/SFRP4/PPT1/CD177/UNC119/STON2/HIP1R/SLC2A4/SH3GL1/CCL2/SYNJ2BP/STX1B/IL15RA/PICK1/PTPRC/CD300LF/LRPAP1/CD47/ACTN4/TLR2/FLOT1/VTN/SCRIB/AP2S1/LRP1/AAK1/RAB27A/RAPGEF1/FPR2/FMR1/DNAJC6/SYT11/CD151/SNX33/SNX12/ATAD1/CYBA/LMAN2/RABGEF1/RUFY2/UBQLN2/CD2AP/ADIPOQ/DNM1/IL4/LRSAM1/LDLRAP1/PACSIN1/ARF6/BCR/NTF3/DLL1/TGFB1/EHD4/DLG4	81
BP	GO:0032365	intracellular lipid transport	15/4749	43/18670	0.1081	0.3482	0.2833	ABCG1/ANXA2P2/ANXA2/LDLR/SGPP1/PRKAB2/ABCA1/PRKAG2/PLEKHA8/CPT1A/ARV1/LDLRAP1/ACACB/LRP6/PLEKHA3	15
BP	GO:0032459	regulation of protein oligomerization	15/4749	43/18670	0.1081	0.3482	0.2833	SNX9/BAX/PMAIP1/SORL1/SRC/TMC8/BMF/CLU/BIK/CCK/BID/GBA/PEX5/CRBN/TRABD2B	15
BP	GO:0050850	positive regulation of calcium-mediated signaling	15/4749	43/18670	0.1081	0.3482	0.2833	CHERP/TNF/SPPL3/PTBP1/CCL3/PKD2/HTT/GSTO1/LMCD1/C10orf71/CAMTA1/LACRT/CD3E/P2RX5/ZAP70	15
BP	GO:1901658	glycosyl compound catabolic process	15/4749	43/18670	0.1081	0.3482	0.2833	NAGA/TYMP/APOBEC3H/APOBEC3B/HPRT1/PNP/FUCA2/GBA/AICDA/ENPP4/DPYD/ENTPD4/NT5E/GUSB/FUCA1	15
BP	GO:0030203	glycosaminoglycan metabolic process	48/4749	160/18670	0.1088	0.3501	0.2848	IL1B/SDC4/HS3ST3B1/HS3ST3A1/CHST15/GLB1/HPSE/GPC1/CHPF2/HYAL3/IDS/PIM1/B3GAT3/OGN/CSGALNACT1/IDUA/SDC2/SLC35D2/SLC35D1/ITIH3/SDC1/PGLYRP3/B3GALT6/B3GNT2/SPOCK3/CHST7/EXT1/EXTL2/CHP1/GPC2/CD44/DSEL/ST3GAL3/HS6ST1/HAS3/CHPF/B4GALT5/HEXB/GUSB/CHST13/FUCA1/XYLT1/ITIH6/TGFB1/HAS2/PDGFB/B4GALT4/B4GALT7	48
BP	GO:0002717	positive regulation of natural killer cell mediated immunity	12/4749	33/18670	0.1094	0.3512	0.2857	IL21/ULBP2/RAET1E/HLA-G/SH2D1A/HLA-E/MICA/LAG3/CADM1/LAMP1/ULBP1/KLRK1	12
BP	GO:0002756	MyD88-independent toll-like receptor signaling pathway	12/4749	33/18670	0.1094	0.3512	0.2857	IRF7/TLR4/UBB/RPS27A/CD300LF/UBA52/TANK/TLR6/PRKCE/IRF3/BIRC3/TNIP3	12
BP	GO:0019692	deoxyribose phosphate metabolic process	12/4749	33/18670	0.1094	0.3512	0.2857	DCTPP1/TYMS/CMPK2/DTYMK/NUDT16/NUDT1/AK5/DCTD/SAMHD1/GUK1/NEIL1/OGG1	12
BP	GO:0030851	granulocyte differentiation	12/4749	33/18670	0.1094	0.3512	0.2857	CSF2/TRIB1/SPI1/CEACAM1/CBFA2T3/ZBTB46/ADIPOQ/TESC/FASN/CUL4A/RARA/ZFPM1	12
BP	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	12/4749	33/18670	0.1094	0.3512	0.2857	RAC1/ARRB1/C2CD2L/SRI/TRPM4/NADK/OXCT1/LRP1/GHRL/PDX1/SYBU/BAD	12
BP	GO:2000758	positive regulation of peptidyl-lysine acetylation	12/4749	33/18670	0.1094	0.3512	0.2857	LIF/IL1B/FOXP3/SMARCB1/NAP1L2/ARRB1/KAT2A/MUC1/TADA2A/SPHK2/TGFB1/GATA3	12
BP	GO:0002374	cytokine secretion involved in immune response	8/4749	20/18670	0.1104	0.3519	0.2863	NLRP3/IL10/HK1/TNF/TLR2/NOD2/TNFRSF1B/SPHK2	8
BP	GO:0010042	response to manganese ion	8/4749	20/18670	0.1104	0.3519	0.2863	HSPA5/TSPO/ATP13A2/ATF4/ARG1/EIF2AK3/D2HGDH/ADAM9	8
BP	GO:0019370	leukotriene biosynthetic process	8/4749	20/18670	0.1104	0.3519	0.2863	ALOX5AP/GGT1/ALOX5/GGTLC2/MGST2/GGT7/MGST3/PLA2G5	8
BP	GO:0032042	mitochondrial DNA metabolic process	8/4749	20/18670	0.1104	0.3519	0.2863	TOP3A/RRM2B/DNAJA3/DNA2/POLG2/SSBP1/ATG7/SESN2	8
BP	GO:0032211	negative regulation of telomere maintenance via telomerase	8/4749	20/18670	0.1104	0.3519	0.2863	SRC/PIF1/TERF1/ACD/CTC1/POT1/TINF2/TERF2	8
BP	GO:0032462	regulation of protein homooligomerization	8/4749	20/18670	0.1104	0.3519	0.2863	SRC/BMF/CLU/BIK/BID/GBA/PEX5/CRBN	8
BP	GO:0039529	RIG-I signaling pathway	8/4749	20/18670	0.1104	0.3519	0.2863	SEC14L1/NPLOC4/BIRC3/C1QBP/ANKRD17/ZCCHC3/USP17L2/TRIM15	8
BP	GO:0051016	barbed-end actin filament capping	8/4749	20/18670	0.1104	0.3519	0.2863	CAPZB/GSN/CAPG/ADD3/TRIOBP/TWF2/CAPZA1/ADD2	8
BP	GO:0051767	nitric-oxide synthase biosynthetic process	8/4749	20/18670	0.1104	0.3519	0.2863	TLR4/MAP2K6/CCL2/NAMPT/TLR2/NOD2/MAP2K4/STAT1	8
BP	GO:0051769	regulation of nitric-oxide synthase biosynthetic process	8/4749	20/18670	0.1104	0.3519	0.2863	TLR4/MAP2K6/CCL2/NAMPT/TLR2/NOD2/MAP2K4/STAT1	8
BP	GO:0060008	Sertoli cell differentiation	8/4749	20/18670	0.1104	0.3519	0.2863	ICAM1/NTRK1/RAB13/SDC1/FNDC3A/SOX8/ARID4A/RARA	8
BP	GO:0070932	histone H3 deacetylation	8/4749	20/18670	0.1104	0.3519	0.2863	SFPQ/SIRT6/PER2/ELK4/SIRT2/HDAC9/SIRT7/SIRT1	8
BP	GO:1901673	regulation of mitotic spindle assembly	8/4749	20/18670	0.1104	0.3519	0.2863	SMC3/CHMP2B/HSPA1A/PLK1/CHMP1A/CHMP2A/SMC1A/CEP97	8
BP	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	8/4749	20/18670	0.1104	0.3519	0.2863	HSPA1A/PTPN1/SYVN1/HERPUD1/PARK7/TXNDC12/BCL2L1/PDX1	8
BP	GO:0030168	platelet activation	46/4749	153/18670	0.1112	0.3539	0.2879	TYRO3/GNA15/TSPAN32/SRF/PDGFA/PTPN6/DGKD/CEACAM1/CD9/YWHAZ/ADRA2B/TLR4/CLIC1/ACTG1/SRC/DGKZ/MERTK/P2RX1/ABAT/F2RL2/ARRB1/GNAS/AXL/FZD6/ENTPD2/BLOC1S4/PIK3R5/VAV2/PRKCA/ADAMTS13/FERMT3/PRKCE/FIBP/MYH9/F2R/HBB/ITGA2B/PRKCB/P2RY1/GNAQ/TRPC7/MAPK1/PDGFB/FYN/ILK/ACTB	46
BP	GO:0034250	positive regulation of cellular amide metabolic process	46/4749	153/18670	0.1112	0.3539	0.2879	ITGA2/LARP4/ABCG1/BCL3/TNF/MTOR/POLDIP3/RPL5/RPL26/CLU/CTIF/NSUN4/CIRBP/PINK1/FASTKD2/CNBP/COA3/RPS9/RXRA/TRUB2/FMR1/ERBB2/RPS4X/VIM/GSK3A/UPF3A/ELAVL1/YTHDF3/EIF2S3/FASTKD3/IFNGR1/ZCCHC4/MIF4GD/UHMK1/PRR16/TRMT10C/SERP1/C1QBP/SPHK2/PPP1R15A/NGRN/EIF3E/RBM3/GUF1/MAPK1/PTAFR	46
BP	GO:0001961	positive regulation of cytokine-mediated signaling pathway	17/4749	50/18670	0.1114	0.3541	0.2881	IRF7/IL1R1/CSF1/HSPA1A/AGPAT2/MMP12/PARP14/AXL/CD74/CD300LF/TRIM44/TXK/CREBRF/IRF3/IL7/TRAF2/RIPK2	17
BP	GO:0032873	negative regulation of stress-activated MAPK cascade	17/4749	50/18670	0.1114	0.3541	0.2881	PBK/FOXM1/DUSP10/SIRPA/DNAJA1/PDCD4/FKTN/FOXO1/PINK1/EZR/CYLD/TAOK3/SFRP1/AIDA/ZNF675/NCOR1/DUSP1	17
BP	GO:0070303	negative regulation of stress-activated protein kinase signaling cascade	17/4749	50/18670	0.1114	0.3541	0.2881	PBK/FOXM1/DUSP10/SIRPA/DNAJA1/PDCD4/FKTN/FOXO1/PINK1/EZR/CYLD/TAOK3/SFRP1/AIDA/ZNF675/NCOR1/DUSP1	17
BP	GO:0006633	fatty acid biosynthetic process	49/4749	164/18670	0.1121	0.356	0.2896	IL1B/PTGIS/ALOX5AP/CEACAM1/ACSM3/ACOT11/FADS3/TECR/ABCD1/MYO5A/MECR/SCD/FA2H/ABCD2/FABP5/MCAT/CD74/EPHX2/TECRL/PRKAB2/HSD17B8/LIAS/ADIPOR2/ALOX5/SLC45A3/INSIG1/ADIPOR1/PRKAG2/GPX4/TBXAS1/ELOVL7/PIBF1/PTGES2/ELOVL1/ASAH2/ABHD1/ADIPOQ/OXSM/ASAH2B/ACACB/ACSS1/FASN/CYP2D6/HPGD/PECR/CYP7A1/DECR2/TRIB3/SIRT1	49
BP	GO:0019319	hexose biosynthetic process	29/4749	92/18670	0.1121	0.356	0.2896	TPI1/GAPDH/CHST15/ENO1/PGAM1/ATF3/GPI/SLC25A1/SDS/CRTC2/ALDOC/CRY1/KAT2A/ATF4/PER2/FOXO1/MDH2/ENO3/MAEA/C1QTNF3/ALDOA/GNMT/ADIPOQ/DGAT2/SLC35B4/ALDOB/CLK2/SESN2/SIRT1	29
BP	GO:0006405	RNA export from nucleus	41/4749	135/18670	0.1121	0.356	0.2896	SEC13/U2AF1/NUP98/SMG5/POLDIP3/IWS1/RNPS1/RPS15/ENY2/SRSF4/NUP153/UPF1/MAGOHB/ABCE1/ALKBH5/SUPT6H/NUP88/THOC3/U2AF1L4/POM121C/NUP205/RAE1/NUP50/DHX38/SDAD1/MAGOH/CPSF1/SMG6/GLE1/CPSF6/NUP93/DDX19A/CDC40/RBM27/NUP35/AAAS/NCBP2/NUP62/SEH1L/YTHDC1/NXF3	41
BP	GO:1901215	negative regulation of neuron death	61/4749	208/18670	0.1131	0.3585	0.2916	KIF14/TYRO3/NR4A3/ADORA2A/NTRK2/IL10/FAIM2/NTRK1/GRN/CNTF/VSTM2L/CDK5/GPNMB/STAMBP/CSF1/FOXB1/CD200/BAX/STAT3/SORL1/HMOX1/PARP2/ARRB1/ATP13A2/AXL/TGFB3/PPT1/ATF4/AMBRA1/CCL2/PINK1/CORO1A/PRKCI/LRP1/GBA/PARK7/JUN/TFAP2B/PPP5C/AGAP2/CEBPB/BCL2L1/MAP2K4/IL13/TRAF2/CD34/TNFRSF1B/F2R/FZD9/GCLC/FGF8/NEFL/NTF3/ATG7/POU4F1/NMNAT1/ADNP/CX3CR1/FYN/ILK/SIRT1	61
BP	GO:0009798	axis specification	27/4749	85/18670	0.1132	0.3585	0.2916	NOTCH1/STIL/AURKA/SRF/PTCH1/SKI/SMAD6/BCOR/TIFAB/TBX6/IFT172/DDIT3/WNT7A/BASP1/EPB41L5/CITED2/NRARP/SFRP1/SETDB2/TDRD5/LRP6/OTX2/FZD5/DLL1/CER1/VAX2/LDB1	27
BP	GO:0048864	stem cell development	27/4749	85/18670	0.1132	0.3585	0.2916	TWIST1/CORO1C/SEMA4C/SEMA7A/SEMA3G/ALX1/SEMA6C/MSI2/SEMA6B/EFNB1/CYP26C1/JAG1/FAM172A/PTPRC/CFL1/NOLC1/WNT7A/SOX8/SOX11/SEMA3B/SEMA5B/SEMA4D/SEMA5A/MAPK1/RDH10/PEF1/LAMA5	27
BP	GO:0045981	positive regulation of nucleotide metabolic process	19/4749	57/18670	0.1133	0.3585	0.2916	CDK1/PFKFB3/ENO1/ENTPD5/STAT3/CCNB1/VCP/HTR2A/PFKFB4/GUCA1C/PINK1/PFKFB2/PARK7/IL4/ISCU/INSR/NUPR1/TAZ/P2RX7	19
BP	GO:0060760	positive regulation of response to cytokine stimulus	19/4749	57/18670	0.1133	0.3585	0.2916	IRF7/IL1R1/CSF1/HSPA1A/TLR4/AGPAT2/MMP12/PARP14/AXL/CD74/CD300LF/TLR2/TRIM44/TXK/CREBRF/IRF3/IL7/TRAF2/RIPK2	19
BP	GO:1900544	positive regulation of purine nucleotide metabolic process	19/4749	57/18670	0.1133	0.3585	0.2916	CDK1/PFKFB3/ENO1/ENTPD5/STAT3/CCNB1/VCP/HTR2A/PFKFB4/GUCA1C/PINK1/PFKFB2/PARK7/IL4/ISCU/INSR/NUPR1/TAZ/P2RX7	19
BP	GO:2000300	regulation of synaptic vesicle exocytosis	25/4749	78/18670	0.1139	0.3604	0.2932	ADORA2A/RIMS3/CDK5/SYN1/NCS1/CHRNA5/P2RX1/SYT4/HTR2A/CAMK2A/PFN2/APBA2/STX1B/DVL1/DRD1/DTNBP1/WNT7A/CNR1/FMR1/SNAPIN/NAPB/PRKCB/P2RY1/CACNB2/FBXL20	25
BP	GO:0061387	regulation of extent of cell growth	34/4749	110/18670	0.1141	0.3607	0.2934	VEGFA/SRF/CYFIP1/CDK5/SPP1/SEMA4C/TNFRSF12A/SEMA7A/CTTN/ZFYVE27/SEMA3G/SEMA6C/NTRK3/PAK1/SEMA6B/FGF13/ARHGAP4/TWF2/L1CAM/LRP1/LIMK1/TTL/SEMA3B/IST1/SEMA5B/PTPRS/SEMA4D/RUFY3/SEMA5A/RTN4R/ADNP/TRPC5/GDI1/ILK	34
BP	GO:0043550	regulation of lipid kinase activity	21/4749	64/18670	0.1142	0.3607	0.2934	KLF4/SOCS2/SRC/SOCS3/DGKZ/AMBRA1/PIK3R5/FLT3/VAV2/NOD2/SLA2/CD19/FLT1/FPR2/AGAP2/RBL2/EEF1A2/PIK3R4/TNFAIP8L3/TGFB1/PDGFB	21
BP	GO:0051291	protein heterooligomerization	39/4749	128/18670	0.1144	0.3607	0.2934	SQSTM1/IKZF4/ANXA2P2/COL6A2/ANXA2/RIPK3/P2RX1/RRM1/CD74/P2RX6/LIMS1/PKD2/XRCC6/COL6A1/HBA2/LRP4/TMEM120B/HSD17B8/TMEM120A/S100A10/GCHFR/C1QTNF6/TRPS1/PPP5C/RCC1/BIRC3/CTNNA1/RRM2/TRAF2/ADIPOQ/HBB/CPSF6/CHMP2A/INSR/WIZ/NUP62/CHMP3/FARSA/ILK	39
BP	GO:0010975	regulation of neuron projection development	139/4749	499/18670	0.1146	0.3607	0.2934	CRMP1/SKIL/VEGFA/MAP6/ITGA3/NTRK2/PTPRF/SIPA1L1/FES/NTRK1/SRF/KLF4/BCL11A/CDC20/PLXNB2/GRN/CYFIP1/CNTF/LZTS1/YWHAH/CAMK1/CDK5/SPP1/GORASP1/SEMA4C/PLXNB1/TNFRSF12A/HSPA5/CREB3L2/LRP8/SEMA7A/PLK2/ZSWIM5/CTTN/NCS1/MTOR/RGMA/CUX1/ZFYVE27/SEMA3G/SCN1B/TIAM1/SYT4/CFLAR/SEMA6C/AMIGO1/NTRK3/DVL3/SDC2/PLXNA1/PAK1/PTK7/CPNE5/ADCY6/MYLIP/CRTC1/SEMA6B/PTPN9/ARHGAP35/LGALS1/CBFA2T2/PTK6/PAK3/PREX1/STX1B/FBXO31/SMURF1/LRP4/CARM1/FGF13/TBX6/TMEM106B/ARHGAP4/PRKCI/TWF2/L1CAM/CFL1/PLXND1/ITGA6/EZH2/SCARF1/DVL1/EFHC2/LRP1/TMEM30A/LIMK1/THY1/ZSWIM6/TTL/WNT7A/STYXL1/CNR1/GPC2/RAPGEF1/STK25/FMR1/UBE3A/CRK/ARHGAP33/CTSZ/SEMA3B/IST1/VIM/SEMA5B/PMP22/GSK3A/RASAL1/BRSK2/RAPGEF2/CHN1/NEGR1/DLG5/SNAPIN/SFRP1/RAP1GAP2/PARP6/LTK/PTPRS/ITM2C/CHRNA3/PACSIN1/SEMA4D/ARF6/LRRC4C/ARHGDIA/LLPH/NEFL/ID1/RUFY3/SEMA5A/RTN4R/ADNP/TRPC5/GATA3/GDI1/FYN/NME2/DLG4/ILK	139
BP	GO:0001522	pseudouridine synthesis	7/4749	17/18670	0.1153	0.3607	0.2934	NOP10/PUS1/TRUB2/RPUSD1/PUSL1/PUS7L/PUS10	7
BP	GO:0006577	amino-acid betaine metabolic process	7/4749	17/18670	0.1153	0.3607	0.2934	TMLHE/BHMT/CPT1A/POR/ALDH7A1/ALDH9A1/SLC22A4	7
BP	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	7/4749	17/18670	0.1153	0.3607	0.2934	FOXM1/CDKN1A/ZNF385A/BRCA2/RPL26/MUC1/CHEK2	7
BP	GO:0030540	female genitalia development	7/4749	17/18670	0.1153	0.3607	0.2934	TYRO3/TP63/BAX/MERTK/AXL/BAK1/ESR1	7
BP	GO:0032460	negative regulation of protein oligomerization	7/4749	17/18670	0.1153	0.3607	0.2934	SORL1/SRC/TMC8/CLU/GBA/PEX5/CRBN	7
BP	GO:0032740	positive regulation of interleukin-17 production	7/4749	17/18670	0.1153	0.3607	0.2934	IL18/IL21/LY9/NOD2/OSM/TGFB1/IL23A	7
BP	GO:0034501	protein localization to kinetochore	7/4749	17/18670	0.1153	0.3607	0.2934	AURKB/TTK/CDK1/CDT1/NDC80/CHAMP1/TRAPPC12	7
BP	GO:0043923	positive regulation by host of viral transcription	7/4749	17/18670	0.1153	0.3607	0.2934	SMARCB1/SMARCA4/SP1/JUN/TAF11/ZNF639/NUCKS1	7
BP	GO:0045072	regulation of interferon-gamma biosynthetic process	7/4749	17/18670	0.1153	0.3607	0.2934	EBI3/CD276/IL21/TLR8/CLEC7A/FOXP3/ZFPM1	7
BP	GO:0045324	late endosome to vacuole transport	7/4749	17/18670	0.1153	0.3607	0.2934	CHMP2B/SNF8/TMEM50A/CHMP1A/CHMP2A/PIK3R4/CHMP3	7
BP	GO:0046500	S-adenosylmethionine metabolic process	7/4749	17/18670	0.1153	0.3607	0.2934	GAMT/MRI1/MTRR/METTL16/GNMT/ENOPH1/BHMT2	7
BP	GO:0048535	lymph node development	7/4749	17/18670	0.1153	0.3607	0.2934	TOX/RIPK3/LTA/IL7R/CD248/TGFB1/CXCR5	7
BP	GO:0051709	regulation of killing of cells of other organism	7/4749	17/18670	0.1153	0.3607	0.2934	GAPDH/CLEC7A/PGLYRP3/ARG1/KRT6A/P2RX7/BAD	7
BP	GO:0051969	regulation of transmission of nerve impulse	7/4749	17/18670	0.1153	0.3607	0.2934	ITGA2/TYMP/HCRT/GPR35/GBA/FMR1/GHRL	7
BP	GO:0061952	midbody abscission	7/4749	17/18670	0.1153	0.3607	0.2934	KIF20A/CEP55/CHMP2B/CHMP1A/CHMP2A/MITD1/CHMP3	7
BP	GO:0071360	cellular response to exogenous dsRNA	7/4749	17/18670	0.1153	0.3607	0.2934	IFIT1/PQBP1/FLOT1/IRF3/COLEC12/RALB/ZCCHC3	7
BP	GO:0099010	modification of postsynaptic structure	7/4749	17/18670	0.1153	0.3607	0.2934	CYFIP1/CHMP2B/MYH10/CAMKV/TIAM1/PFN2/STAU1	7
BP	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	7/4749	17/18670	0.1153	0.3607	0.2934	CDK5/NCS1/P2RX1/CNR1/CALB2/P2RY1/CACNB2	7
BP	GO:0050832	defense response to fungus	14/4749	40/18670	0.1154	0.3607	0.2934	IL17A/GAPDH/RNASE8/COTL1/ARG1/IL17RC/DEFB114/MPO/HTN3/RARRES2/S100A8/DEFA1B/DEFA4/TGFB1	14
BP	GO:0071470	cellular response to osmotic stress	14/4749	40/18670	0.1154	0.3607	0.2934	RELB/SERPINB6/SLC25A23/TSPO/ARHGEF2/MICU1/PKD2/XRCC6/SLC2A4/BDKRB2/ZFP36L1/SLC12A6/LRRC8D/BAD	14
BP	GO:0032652	regulation of interleukin-1 production	32/4749	103/18670	0.1159	0.3622	0.2946	EGR1/NLRP3/IL10/ACP5/TLR8/HK1/SIRPA/CLEC7A/CEACAM1/LGALS9/PML/HMGB1/TLR4/LILRA2/IL1R2/CCL3/HAVCR2/CD33/NOD2/MNDA/ZC3H12A/LILRA5/IFI16/GHRL/RIPK2/F2R/TYROBP/CARD8/FZD5/TRIM16/P2RX7/CX3CR1	32
BP	GO:0035304	regulation of protein dephosphorylation	42/4749	139/18670	0.116	0.3625	0.2949	PPP1R14A/LGALS3/YWHAE/PPP2R1A/PPP1R14B/TNF/SPPL3/MTOR/SWAP70/CDCA2/B3GAT3/PTBP1/CD33/URI1/BOD1/IGFBP3/HTT/PHACTR2/PINK1/PTPRC/ITGA1/TIPRL/LILRB2/FKBP1A/GBA/GNAI2/STYXL1/PPP1R16B/CAMTA1/MGAT5/PPP1R8/PPP1R26/PPP2R3B/PPP1R15A/PPP1R9B/SLC39A10/TGFB1/PPP1R12A/PPP1R2/CDH5/PPP6R1/PPP1R3B	42
BP	GO:0010743	regulation of macrophage derived foam cell differentiation	11/4749	30/18670	0.1165	0.3625	0.2949	IL18/CSF2/PPARG/ABCG1/CSF1/ABCA1/NFKBIA/ABCA5/ADIPOQ/PLA2G2A/CETP	11
BP	GO:0044818	mitotic G2/M transition checkpoint	11/4749	30/18670	0.1165	0.3625	0.2949	TICRR/CDK1/CLSPN/CDC6/ORC1/TOPBP1/TAOK3/ZNF830/NAE1/ATM/SYF2	11
BP	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	11/4749	30/18670	0.1165	0.3625	0.2949	IL21/ULBP2/RAET1E/SH2D1A/HLA-E/MICA/LAG3/CADM1/LAMP1/ULBP1/KLRK1	11
BP	GO:0046640	regulation of alpha-beta T cell proliferation	11/4749	30/18670	0.1165	0.3625	0.2949	EBI3/IL18/TNFSF4/LGALS9/CCR2/PTPRC/HLA-E/CD3E/RIPK2/ZAP70/IL23A	11
BP	GO:0061082	myeloid leukocyte cytokine production	11/4749	30/18670	0.1165	0.3625	0.2949	NR4A3/BCL6/SEMA7A/TLR4/HMOX1/HLA-G/TGFB3/CD74/IRAK3/TGFB1/SIRT1	11
BP	GO:0097421	liver regeneration	11/4749	30/18670	0.1165	0.3625	0.2949	SULF2/AURKA/IL10/PTCH1/TYMS/HMOX1/EZH2/VTN/CEBPB/TGFB1/CCND1	11
BP	GO:1904893	negative regulation of STAT cascade	11/4749	30/18670	0.1165	0.3625	0.2949	BCL3/NF2/PPP2R1A/SOCS2/PARP14/SOCS3/PPP2CA/ADIPOR1/HGS/GGNBP2/PIBF1	11
BP	GO:0048675	axon extension	37/4749	121/18670	0.1166	0.3628	0.2952	VEGFA/SRF/CYFIP1/CDK5/SEMA4C/TNFRSF12A/SEMA7A/CTTN/USP9X/ZFYVE27/SEMA3G/SEMA6C/NTRK3/PAK1/SEMA6B/ARHGAP4/TWF2/L1CAM/DVL1/ULK1/LRP1/LIMK1/TTL/NDN/SEMA3B/SEMA5B/PTPRS/SEMA4D/RAPH1/RUFY3/SEMA5A/RTN4R/ADNP/TRPC5/GDI1/ILK/SLC9A6	37
BP	GO:0097327	response to antineoplastic agent	30/4749	96/18670	0.1176	0.3642	0.2963	EGR1/ICAM1/CASP9/TREX1/EIF4EBP1/RAD51/NR3C1/HMOX1/CFLAR/ASNS/FOXO1/NUCB1/DHFR/DDIT4/TIMELESS/RECQL5/GBA/ARG1/FMR1/ZC3H12A/ADAM15/CTNNA1/DDX11/MAP4K1/SPHK2/NEFL/TGFB1/ADAM9/PDGFB/PTAFR	30
BP	GO:0018393	internal peptidyl-lysine acetylation	48/4749	161/18670	0.1181	0.3642	0.2963	TWIST1/LIF/IL1B/GTF3C4/IRF4/SPI1/DPF3/BRCA2/PHF10/FOXP3/SMARCB1/CRTC2/ING3/NAP1L2/ING5/KANSL3/IWS1/ARRB1/MORF4L2/KANSL1L/KAT2A/ACTL6A/TAF1L/YEATS4/SUPT3H/TAF9B/MUC1/TAF6L/TAF10/CHEK1/MCRS1/BRPF3/TAF7/KAT6B/POR/DPF1/TADA2A/SPHK2/CTBP1/TGFB1/ZNF451/TRIM16/LDB1/GATA3/CPA4/TADA1/KAT6A/SIRT1	48
BP	GO:0003158	endothelium development	40/4749	132/18670	0.1185	0.3642	0.2963	IL1B/VEGFA/NOTCH1/ICAM1/ANXA2P2/CEACAM1/TNF/CXCL10/PROC/COL18A1/TJP2/ANXA2/MYADM/GPX1/ITGAX/PDE4D/RBPJ/S1PR1/STARD13/JAG1/EZR/ATOH8/WNT7A/PPP1R16B/RAPGEF1/ACVR2B/SCUBE1/RAPGEF2/CD34/PTPRS/EDF1/FASN/PLOD3/DLL1/ID1/CDH5/LAMA5/SLC40A1/ARHGEF26/GJA5	40
BP	GO:0007127	meiosis I	35/4749	114/18670	0.1188	0.3642	0.2963	ESPL1/TOP2A/AURKA/HSPA2/TRIP13/PTTG1/RAD54L/SYCE3/SLC2A8/BRCA2/UBE2B/PLK1/RAD51/TDRD9/CKS2/FBXO5/DMC1/UBB/MND1/CCNE2/TERF1/HELQ/REC8/STAG3/EME1/KLHDC3/SYCE2/UBR2/DMRTC2/ANKRD31/ATM/MLH3/RNF212/CDC25B/RAD54B	35
BP	GO:0060349	bone morphogenesis	35/4749	114/18670	0.1188	0.3642	0.2963	TWIST1/ACP5/ANXA2P2/COL6A2/SKI/ANXA2/MSX1/NAB2/CSGALNACT1/GNAS/SFRP4/TGFB3/POC1A/COL6A1/RUNX2/CARM1/TIFAB/MEF2D/INSIG1/NAB1/LRP5L/RAB23/IFT80/PAX1/POR/DLX5/LRP6/HOXA11/AXIN2/TMEM119/CER1/TGFB1/HAS2/RARA/DHRS3	35
BP	GO:0070231	T cell apoptotic process	16/4749	47/18670	0.1189	0.3642	0.2963	PDCD1/LGALS3/PRELID1/LGALS9/IL2RA/BAX/DOCK8/RIPK3/RPS6/DNAJA3/BAK1/IL7R/IDO1/GIMAP8/TSC22D3/JAK3	16
BP	GO:1901068	guanosine-containing compound metabolic process	16/4749	47/18670	0.1189	0.3642	0.2963	TJP2/HPRT1/AK3/NME4/NME3/AK4/MOCS1/IMPDH1/LRGUK/RAB23/CARD11/GUK1/AMPD3/NFS1/NME9/NME2	16
BP	GO:0006094	gluconeogenesis	28/4749	89/18670	0.1191	0.3642	0.2963	TPI1/GAPDH/ENO1/PGAM1/ATF3/GPI/SLC25A1/SDS/CRTC2/ALDOC/CRY1/KAT2A/ATF4/PER2/FOXO1/MDH2/ENO3/MAEA/C1QTNF3/ALDOA/GNMT/ADIPOQ/DGAT2/SLC35B4/ALDOB/CLK2/SESN2/SIRT1	28
BP	GO:0046427	positive regulation of JAK-STAT cascade	28/4749	89/18670	0.1191	0.3642	0.2963	LIF/NOTCH1/IL18/CSF2/IL21/CSF1R/IL10/TNFRSF18/CNTF/TNF/STAT3/PARP14/SOCS3/FLT3/PTK6/ADIPOR1/IL26/OSM/PIBF1/IL13/IL20/IL4/ARL2BP/F2R/CRLF3/IL10RA/FYN/IL23A	28
BP	GO:0006241	CTP biosynthetic process	6/4749	14/18670	0.1194	0.3642	0.2963	NME4/NME3/CTPS2/UCK2/NME9/NME2	6
BP	GO:0021692	cerebellar Purkinje cell layer morphogenesis	6/4749	14/18670	0.1194	0.3642	0.2963	KIF14/FAIM2/CEND1/AGTPBP1/DLL1/LDB1	6
BP	GO:0031937	positive regulation of chromatin silencing	6/4749	14/18670	0.1194	0.3642	0.2963	SIRT6/MORC2/ZNF304/PPHLN1/SETDB1/SIRT1	6
BP	GO:0032785	negative regulation of DNA-templated transcription, elongation	6/4749	14/18670	0.1194	0.3642	0.2963	EZH2/RECQL5/RNF8/POU4F1/EAPP/RNF168	6
BP	GO:0040034	regulation of development, heterochronic	6/4749	14/18670	0.1194	0.3642	0.2963	NOTCH1/ASCL1/FGF9/RBPJ/GDPD5/DLL1	6
BP	GO:0044546	NLRP3 inflammasome complex assembly	6/4749	14/18670	0.1194	0.3642	0.2963	NLRP3/TLR4/DHX33/TLR6/NLRC3/SIRT2	6
BP	GO:0046036	CTP metabolic process	6/4749	14/18670	0.1194	0.3642	0.2963	NME4/NME3/CTPS2/UCK2/NME9/NME2	6
BP	GO:0046037	GMP metabolic process	6/4749	14/18670	0.1194	0.3642	0.2963	TJP2/HPRT1/IMPDH1/LRGUK/CARD11/GUK1	6
BP	GO:0048308	organelle inheritance	6/4749	14/18670	0.1194	0.3642	0.2963	CDK1/YWHAZ/STX5/STK25/GBF1/MAPK1	6
BP	GO:0048313	Golgi inheritance	6/4749	14/18670	0.1194	0.3642	0.2963	CDK1/YWHAZ/STX5/STK25/GBF1/MAPK1	6
BP	GO:0071361	cellular response to ethanol	6/4749	14/18670	0.1194	0.3642	0.2963	SPI1/CYBB/KCNMB1/TP53INP1/PRKCE/CCL7	6
BP	GO:0072216	positive regulation of metanephros development	6/4749	14/18670	0.1194	0.3642	0.2963	EGR1/LIF/PDGFA/BASP1/ADIPOQ/PDGFB	6
BP	GO:0072425	signal transduction involved in G2 DNA damage checkpoint	6/4749	14/18670	0.1194	0.3642	0.2963	DTL/PLK1/BRCC3/CHEK1/CDC14B/ATM	6
BP	GO:0090231	regulation of spindle checkpoint	6/4749	14/18670	0.1194	0.3642	0.2963	CDT1/CCNB1/NDC80/USP44/XRCC3/DUSP1	6
BP	GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint	6/4749	14/18670	0.1194	0.3642	0.2963	CDT1/CCNB1/NDC80/USP44/XRCC3/DUSP1	6
BP	GO:0099171	presynaptic modulation of chemical synaptic transmission	6/4749	14/18670	0.1194	0.3642	0.2963	CDK5/CNR1/PRKCB/CACNB2/FBXL20/RPL22	6
BP	GO:0099188	postsynaptic cytoskeleton organization	6/4749	14/18670	0.1194	0.3642	0.2963	MYH10/ACTG1/INA/NEFL/WASF2/ACTB	6
BP	GO:1903504	regulation of mitotic spindle checkpoint	6/4749	14/18670	0.1194	0.3642	0.2963	CDT1/CCNB1/NDC80/USP44/XRCC3/DUSP1	6
BP	GO:0006636	unsaturated fatty acid biosynthetic process	18/4749	54/18670	0.1209	0.3642	0.2963	IL1B/PTGIS/ALOX5AP/FADS3/ABCD1/SCD/ABCD2/FABP5/CD74/ALOX5/TBXAS1/ELOVL7/PIBF1/PTGES2/ELOVL1/HPGD/DECR2/SIRT1	18
BP	GO:0010524	positive regulation of calcium ion transport into cytosol	18/4749	54/18670	0.1209	0.3642	0.2963	BAX/CXCL10/TRPC1/SRI/PKD2/HTT/GSTO1/CXCL9/BAK1/DRD1/THY1/CD19/NTSR1/LACRT/IL13/P2RX5/F2R/P2RX7	18
BP	GO:0035384	thioester biosynthetic process	18/4749	54/18670	0.1209	0.3642	0.2963	PDPR/SLC25A1/TECR/SCD/PDHB/PPT1/ACSL1/PDHX/HSD17B8/DLAT/ELOVL7/ELOVL1/ACSL4/ACACB/ACSS1/FASN/MPC1/GSTZ1	18
BP	GO:0070206	protein trimerization	18/4749	54/18670	0.1209	0.3642	0.2963	SLC1A5/ALOX5AP/COL6A2/SKI/HLA-G/CD74/COL6A1/TRIM22/CLYBL/TRIM4/HSF4/C1QTNF6/ARG1/C1QTNF3/TRAF2/ADIPOQ/WIZ/NUP62	18
BP	GO:0071616	acyl-CoA biosynthetic process	18/4749	54/18670	0.1209	0.3642	0.2963	PDPR/SLC25A1/TECR/SCD/PDHB/PPT1/ACSL1/PDHX/HSD17B8/DLAT/ELOVL7/ELOVL1/ACSL4/ACACB/ACSS1/FASN/MPC1/GSTZ1	18
BP	GO:0048524	positive regulation of viral process	33/4749	107/18670	0.1209	0.3642	0.2963	NOTCH1/TOP2A/CSF1R/IFIT1/ANXA2P2/LGALS9/SMC3/CHMP2B/KPNA2/ANXA2/SMARCB1/PPIH/CD74/LGALS1/SMARCA4/TBC1D20/CFL1/SP1/POLR2I/JUN/FMR1/TAF11/RAD23A/ZNF639/POLR2C/CNOT7/CHMP2A/STAU1/POLR2J/STOM/NUCKS1/POLR2A/CHMP3	33
BP	GO:0033673	negative regulation of kinase activity	74/4749	257/18670	0.1213	0.3642	0.2963	IL1B/CDKN1A/WNK1/MVP/DUSP10/CAMK2N2/ADORA2A/DUSP4/TRIB1/CDKN2B/GSKIP/PTPN6/DUSP6/SPRED2/HEXIM1/DNAJA1/CEACAM1/CORO1C/NF2/PPP2R1A/PTPN1/PLK1/CDKN2C/GADD45A/PDCD4/SORL1/SOCS3/FGFR1OP/PRDX3/DUSP5/SFN/IGF1R/WWTR1/IRAK3/PTK6/DUSP16/PTPRC/SH3BP5L/DUSP22/DVL1/PPP2CA/CHORDC1/CDKN2A/GBA/DTNBP1/THY1/TAOK3/PRKAG2/CHP1/PARK7/GGNBP2/DEFB114/DEPTOR/DUSP18/SFRP1/ADIPOQ/TAF7/TESC/AIDA/LRP6/STK38/GNAQ/DUSP14/APC/ZNF675/COX11/UCHL1/NUP62/PAK2/TRIB3/ILK/SIRT1/DUSP1/NPRL2	74
BP	GO:0032482	Rab protein signal transduction	24/4749	75/18670	0.1213	0.3642	0.2963	RAB31/RAB33A/SGSM3/RABL2A/RAB32/RAB13/RAB3D/RAB19/RAB27A/IFT27/RAB38/RAB39B/RAB23/RAB2A/RAB40B/RAB40C/RAB15/RAB1A/RAB34/RAB37/GDI1/RAB28/RAB1B/RAB12	24
BP	GO:0043242	negative regulation of protein complex disassembly	24/4749	75/18670	0.1213	0.3642	0.2963	CAPZB/TNF/GSN/CKAP2/SWAP70/TMOD2/CAPG/ARHGEF2/ADD3/IRAK3/SPTBN1/FGF13/CLASP2/TRIOBP/TWF2/SPTAN1/MID1/CAPZA1/TRIM54/VILL/SCAF4/APC/PHF23/ADD2	24
BP	GO:0001731	formation of translation preinitiation complex	5/4749	11/18670	0.1217	0.3642	0.2963	TICRR/EIF4H/EIF2D/EIF2S3/DENR	5
BP	GO:0002887	negative regulation of myeloid leukocyte mediated immunity	5/4749	11/18670	0.1217	0.3642	0.2963	LGALS9/CCR2/HMOX1/RABGEF1/BCR	5
BP	GO:0006183	GTP biosynthetic process	5/4749	11/18670	0.1217	0.3642	0.2963	NME4/NME3/IMPDH1/NME9/NME2	5
BP	GO:0009113	purine nucleobase biosynthetic process	5/4749	11/18670	0.1217	0.3642	0.2963	MTHFD1L/HPRT1/MTHFD1/APRT/PRPS1	5
BP	GO:0009151	purine deoxyribonucleotide metabolic process	5/4749	11/18670	0.1217	0.3642	0.2963	NUDT16/NUDT1/AK5/SAMHD1/GUK1	5
BP	GO:0009629	response to gravity	5/4749	11/18670	0.1217	0.3642	0.2963	FOSL1/PKM/BGLAP/FOS/PTAFR	5
BP	GO:0018202	peptidyl-histidine modification	5/4749	11/18670	0.1217	0.3642	0.2963	DPH5/DPH1/DNAJC24/HIF1AN/NME2	5
BP	GO:0019852	L-ascorbic acid metabolic process	5/4749	11/18670	0.1217	0.3642	0.2963	SLC2A3/GSTO1/SLC23A2/GCLC/AKR1A1	5
BP	GO:0021892	cerebral cortex GABAergic interneuron differentiation	5/4749	11/18670	0.1217	0.3642	0.2963	ASCL1/NKX2-1/DRD1/LHX6/RAC3	5
BP	GO:0031652	positive regulation of heat generation	5/4749	11/18670	0.1217	0.3642	0.2963	IL1B/TNF/ABAT/CNR1/TNFSF11	5
BP	GO:0033234	negative regulation of protein sumoylation	5/4749	11/18670	0.1217	0.3642	0.2963	PIAS3/PARK7/HMG20A/HMG20B/MAGEA2B	5
BP	GO:0033629	negative regulation of cell adhesion mediated by integrin	5/4749	11/18670	0.1217	0.3642	0.2963	WNK1/SERPINE1/SWAP70/MUC1/ACER2	5
BP	GO:0040015	negative regulation of multicellular organism growth	5/4749	11/18670	0.1217	0.3642	0.2963	PLAC8/BBS2/PTCH1/SOCS2/FXN	5
BP	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity	5/4749	11/18670	0.1217	0.3642	0.2963	ULBP2/RAET1E/MICA/CADM1/ULBP1	5
BP	GO:0042482	positive regulation of odontogenesis	5/4749	11/18670	0.1217	0.3642	0.2963	CSF1/AMTN/CD34/TGFB1/AMELX	5
BP	GO:0043129	surfactant homeostasis	5/4749	11/18670	0.1217	0.3642	0.2963	VEGFA/CTSH/RCN3/NAPSA/EPAS1	5
BP	GO:0045217	cell-cell junction maintenance	5/4749	11/18670	0.1217	0.3642	0.2963	CSF1R/CD177/PLEKHA7/F2R/PARD6A	5
BP	GO:0045351	type I interferon biosynthetic process	5/4749	11/18670	0.1217	0.3642	0.2963	IRF7/IL10/TLR8/TLR4/IRF3	5
BP	GO:0045835	negative regulation of meiotic nuclear division	5/4749	11/18670	0.1217	0.3642	0.2963	LIF/TTK/TRIP13/FBXO43/FBXO5	5
BP	GO:0046051	UTP metabolic process	5/4749	11/18670	0.1217	0.3642	0.2963	AK3/NME4/NME3/NME9/NME2	5
BP	GO:0046607	positive regulation of centrosome cycle	5/4749	11/18670	0.1217	0.3642	0.2963	PLK4/CENPJ/POC1A/NSFL1C/NUP62	5
BP	GO:0046886	positive regulation of hormone biosynthetic process	5/4749	11/18670	0.1217	0.3642	0.2963	EGR1/IL1B/TNF/ADM/POR	5
BP	GO:0048680	positive regulation of axon regeneration	5/4749	11/18670	0.1217	0.3642	0.2963	GRN/CNTF/NTRK3/SCARF1/LRP1	5
BP	GO:0051561	positive regulation of mitochondrial calcium ion concentration	5/4749	11/18670	0.1217	0.3642	0.2963	SLC25A23/TGM2/ATP2A1/MICU1/BCAP31	5
BP	GO:0051974	negative regulation of telomerase activity	5/4749	11/18670	0.1217	0.3642	0.2963	PPARG/SRC/PIF1/TERF1/POT1	5
BP	GO:0055015	ventricular cardiac muscle cell development	5/4749	11/18670	0.1217	0.3642	0.2963	CDK1/MYH10/LMNA/CCNB1/BMP10	5
BP	GO:0055091	phospholipid homeostasis	5/4749	11/18670	0.1217	0.3642	0.2963	ABCG1/TLCD1/ABCA1/RCN3/CETP	5
BP	GO:0061085	regulation of histone H3-K27 methylation	5/4749	11/18670	0.1217	0.3642	0.2963	PHF19/ZNF304/EED/SUPT6H/GATA3	5
BP	GO:0070213	protein auto-ADP-ribosylation	5/4749	11/18670	0.1217	0.3642	0.2963	TNKS2/PARP16/PARP11/PARP6/PARP8	5
BP	GO:0070475	rRNA base methylation	5/4749	11/18670	0.1217	0.3642	0.2963	NSUN5P1/TRMT112/EMG1/FDXACB1/METTL16	5
BP	GO:0071803	positive regulation of podosome assembly	5/4749	11/18670	0.1217	0.3642	0.2963	FSCN1/CSF2/TNF/SRC/ARHGEF5	5
BP	GO:0072321	chaperone-mediated protein transport	5/4749	11/18670	0.1217	0.3642	0.2963	CLIP3/TIMM10/CLU/BAG3/TIMM9	5
BP	GO:0090084	negative regulation of inclusion body assembly	5/4749	11/18670	0.1217	0.3642	0.2963	HSPA2/HSPA1A/SORL1/DNAJB6/DNAJB2	5
BP	GO:1901077	regulation of relaxation of muscle	5/4749	11/18670	0.1217	0.3642	0.2963	PDE4D/PDE4B/SRI/TIFAB/CAMK2D	5
BP	GO:1901569	fatty acid derivative catabolic process	5/4749	11/18670	0.1217	0.3642	0.2963	ABHD16A/ABCD1/OXCT1/OXCT2/CYP4F12	5
BP	GO:1903977	positive regulation of glial cell migration	5/4749	11/18670	0.1217	0.3642	0.2963	CSF1/CCR2/TIAM1/CCL3/LRP1	5
BP	GO:1904468	negative regulation of tumor necrosis factor secretion	5/4749	11/18670	0.1217	0.3642	0.2963	IL27RA/DEFB114/SYT11/ZC3H12A/GHRL	5
BP	GO:1905146	lysosomal protein catabolic process	5/4749	11/18670	0.1217	0.3642	0.2963	LDLR/ATP13A2/LRP1/GBA/CCDC115	5
BP	GO:1905820	positive regulation of chromosome separation	5/4749	11/18670	0.1217	0.3642	0.2963	ESPL1/CDT1/DLGAP5/NUMA1/ANAPC11	5
BP	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	5/4749	11/18670	0.1217	0.3642	0.2963	LGALS9/GSN/BAX/FAS/ST18	5
BP	GO:0032370	positive regulation of lipid transport	20/4749	61/18670	0.1218	0.3642	0.2963	IL1B/ABCG1/ANXA2P2/PRELID1/SPP1/PTCH1/ANXA2/MAP2K6/ABCA1/LRP1/NTSR1/ABCB4/NFKBIA/GHRL/ADIPOQ/LDLRAP1/TNFSF11/TMF1/P2RX7/SIRT1	20
BP	GO:0006625	protein targeting to peroxisome	22/4749	68/18670	0.1218	0.3642	0.2963	MPV17/USP9X/SLC27A2/UBB/HMGCL/EPHX2/ACOX2/TYSND1/RPS27A/ACOT8/UBA52/AMACR/PEX2/PEX3/PEX5/GSTK1/NUDT19/PECR/PEX13/PEX1/DECR2/ZFAND6	22
BP	GO:0033866	nucleoside bisphosphate biosynthetic process	22/4749	68/18670	0.1218	0.3642	0.2963	PDPR/SLC25A1/TECR/SCD/PDHB/PPT1/ACSL1/PDHX/HSD17B8/SLC35B2/DLAT/ELOVL7/ELOVL1/ACSL4/PANK4/ACACB/ACSS1/FASN/PAPSS2/PANK1/MPC1/GSTZ1	22
BP	GO:0034030	ribonucleoside bisphosphate biosynthetic process	22/4749	68/18670	0.1218	0.3642	0.2963	PDPR/SLC25A1/TECR/SCD/PDHB/PPT1/ACSL1/PDHX/HSD17B8/SLC35B2/DLAT/ELOVL7/ELOVL1/ACSL4/PANK4/ACACB/ACSS1/FASN/PAPSS2/PANK1/MPC1/GSTZ1	22
BP	GO:0034033	purine nucleoside bisphosphate biosynthetic process	22/4749	68/18670	0.1218	0.3642	0.2963	PDPR/SLC25A1/TECR/SCD/PDHB/PPT1/ACSL1/PDHX/HSD17B8/SLC35B2/DLAT/ELOVL7/ELOVL1/ACSL4/PANK4/ACACB/ACSS1/FASN/PAPSS2/PANK1/MPC1/GSTZ1	22
BP	GO:0050918	positive chemotaxis	22/4749	68/18670	0.1218	0.3642	0.2963	VEGFA/ITGA2/LGALS3/GPNMB/HMGB1/CXCL10/CCR4/CCL3/NTRK3/S1PR1/CASR/CORO1A/SCRIB/LRP1/FPR2/F3/FGF8/NTF3/SEMA5A/CCL15/PDGFB/VEGFC	22
BP	GO:0072662	protein localization to peroxisome	22/4749	68/18670	0.1218	0.3642	0.2963	MPV17/USP9X/SLC27A2/UBB/HMGCL/EPHX2/ACOX2/TYSND1/RPS27A/ACOT8/UBA52/AMACR/PEX2/PEX3/PEX5/GSTK1/NUDT19/PECR/PEX13/PEX1/DECR2/ZFAND6	22
BP	GO:0072663	establishment of protein localization to peroxisome	22/4749	68/18670	0.1218	0.3642	0.2963	MPV17/USP9X/SLC27A2/UBB/HMGCL/EPHX2/ACOX2/TYSND1/RPS27A/ACOT8/UBA52/AMACR/PEX2/PEX3/PEX5/GSTK1/NUDT19/PECR/PEX13/PEX1/DECR2/ZFAND6	22
BP	GO:0031589	cell-substrate adhesion	100/4749	354/18670	0.1227	0.3665	0.2981	KIF14/VEGFA/NOTCH1/SDC4/TYRO3/ITGA2/ITGA3/NEDD9/SRF/RAC1/BCL6/EPHB1/ZYX/HPSE/CDK5/CORO1C/NF2/TNFRSF12A/CSF1/SRGAP2/CTTN/PLAU/NINJ1/SERPINE1/MYADM/MMP12/SRC/MERTK/TIAM1/TRIP6/DOCK1/AXL/LIMS1/NID1/DOCK5/SMAD6/LGALS1/EMILIN2/PRKX/JAG1/PREX1/CORO1A/CLASP2/WDPCP/ITGA1/TRIOBP/PLEKHA2/ADAMTS13/L1CAM/LIMCH1/PARVB/ITGA6/ACTN4/DUSP22/VTN/S100A10/FERMT3/CDKN2A/LRP1/THY1/UNC13D/EPB41L5/CD44/CRK/PRKCE/RAC2/VAMP3/ACER2/STRC/MSLN/MINK1/ADAM15/DDR1/CD3E/ADAMTS9/SFRP1/CD34/FER/ITGA2B/UTRN/C1QBP/RAB1A/BCR/ARL2/SORBS3/WHAMM/PPARD/AP1AR/PIP5K1A/ID1/BCAS3/CDC42/HAS2/ADAM9/FMN1/LAMA5/CD96/LDB1/ILK/RAC3	100
BP	GO:0060560	developmental growth involved in morphogenesis	68/4749	235/18670	0.1229	0.3669	0.2985	VEGFA/NOTCH1/AURKA/SRF/BCL11A/CYFIP1/CDK5/SPP1/SEMA4C/TNFRSF12A/CSF1/SIRT6/SEMA7A/CTTN/USP9X/ZFYVE27/SEMA3G/CYFIP2/NKD1/TIAM1/SYT4/SEMA6C/NTRK3/PLXNA1/PAK1/PTK7/CPNE5/SEMA6B/S1PR1/SMURF1/FGF13/KDM5B/ARHGAP4/TWF2/L1CAM/DVL1/ULK1/LRP1/LIMK1/TTL/EPB41L5/NDN/SEMA3B/IST1/YAP1/DDR1/SEMA5B/RASAL1/SFRP1/ESR1/PTPRS/LRP6/SEMA4D/MED12/LLPH/RAPH1/RUFY3/TGFB1/SEMA5A/KIF26B/RTN4R/ADNP/TRPC5/RDH10/FMN1/GDI1/ILK/SLC9A6	68
BP	GO:0034446	substrate adhesion-dependent cell spreading	31/4749	100/18670	0.123	0.3669	0.2985	KIF14/TYRO3/NEDD9/RAC1/CORO1C/SRGAP2/MYADM/SRC/MERTK/DOCK1/AXL/LIMS1/DOCK5/PREX1/TRIOBP/PARVB/ACTN4/S100A10/FERMT3/UNC13D/CRK/VAMP3/FER/C1QBP/RAB1A/AP1AR/CDC42/HAS2/LAMA5/ILK/RAC3	31
BP	GO:0120034	positive regulation of plasma membrane bounded cell projection assembly	31/4749	100/18670	0.123	0.3669	0.2985	CDC42EP4/ANLN/FSCN1/SRF/RAC1/CYFIP1/KCTD17/CENPJ/MTOR/CDC42EP1/TENM1/ATMIN/TGFB3/HTT/ARHGAP35/EPS8L2/TWF2/ZMYND10/ARAP1/RALA/PLEKHM1/FMR1/MARK4/RAC2/WRAP73/APC/WASF2/BCAS3/C15orf62/CDC42/P2RX7	31
BP	GO:0030212	hyaluronan metabolic process	13/4749	37/18670	0.1232	0.3673	0.2988	IL1B/HYAL3/PIM1/ITIH3/CHP1/CD44/HAS3/HEXB/GUSB/ITIH6/TGFB1/HAS2/PDGFB	13
BP	GO:0051084	'de novo' posttranslational protein folding	13/4749	37/18670	0.1232	0.3673	0.2988	HSPA2/HSPA5/HSPA1A/DNAJB5/ENTPD5/HSPA9/DNAJB12/CD74/HSPA6/HSPA1L/HSPA14/DNAJB4/CHCHD4	13
BP	GO:0071236	cellular response to antibiotic	44/4749	147/18670	0.1237	0.3684	0.2997	EGR1/PPIF/CDK1/NR4A3/KLF2/IL10/KLF4/SPI1/SIRPA/HSPA5/CRIP1/CYBB/MAP1LC3A/PLEKHA1/RIPK3/FXN/SRC/CLU/AXL/ADCY6/RPS3/NQO1/FOXO1/KCNMB1/CBX8/MAP3K5/RPL23/PINK1/EZH2/TIMELESS/TP53INP1/ARG1/PARK7/STK25/PPP5C/PRKCE/ECT2/ADCY3/ZC3H12A/DDX11/CCL7/NET1/PDGFB/SIRT1	44
BP	GO:0031167	rRNA methylation	10/4749	27/18670	0.124	0.3688	0.3001	NSUN4/NSUN5P1/TRMT112/EMG1/FBL/FDXACB1/RRNAD1/METTL16/ZCCHC4/TFB2M	10
BP	GO:0036336	dendritic cell migration	10/4749	27/18670	0.124	0.3688	0.3001	CCR1/LGALS9/HMGB1/DOCK8/CCR6/CCR2/ARHGEF5/CCR5/TRPM4/C1QBP	10
BP	GO:1901623	regulation of lymphocyte chemotaxis	10/4749	27/18670	0.124	0.3688	0.3001	CXCL13/WNK1/CXCL10/CCR2/CCL3/CCL2/PADI2/CCL7/KLRK1/CCL27	10
BP	GO:0018394	peptidyl-lysine acetylation	50/4749	169/18670	0.1248	0.3711	0.3019	TWIST1/LIF/IL1B/GTF3C4/IRF4/SPI1/DPF3/BRCA2/PHF10/FOXP3/SMARCB1/CRTC2/ING3/NAP1L2/ING5/KANSL3/IWS1/ARRB1/MORF4L2/KANSL1L/BLOC1S1/KAT2A/ACTL6A/TAF1L/YEATS4/SUPT3H/TAF9B/MUC1/TAF6L/TAF10/CHEK1/MCRS1/BRPF3/TAF7/KAT6B/POR/DPF1/TADA2A/SPHK2/CTBP1/TGFB1/ZNF451/TRIM16/LDB1/GATA3/CPA4/TADA1/HINT2/KAT6A/SIRT1	50
BP	GO:0033273	response to vitamin	29/4749	93/18670	0.1249	0.3712	0.302	VDR/PPARG/ITGA2/KANK2/FES/SPP1/TYMS/ASCL1/GSN/CXCL10/TRIM25/GDAP1/TSPO/PIM1/PHEX/CASR/ARG1/CYP27B1/BGLAP/SFRP1/NNT/OGG1/PPARD/TGFB1/MGMT/RARA/CCND1/SETDB1/PDX1	29
BP	GO:0001837	epithelial to mesenchymal transition	42/4749	140/18670	0.1265	0.3758	0.3057	TWIST1/IL1B/NOTCH1/FAM83D/TGFB1I1/MTOR/MSX1/SMAD7/PDCD4/SNAI1/NKX2-1/ALX1/TIAM1/TRIM62/SDCBP/TGFB3/WWTR1/RBPJ/JAG1/CLASP2/EZH2/PPP2CA/ADIPOR1/NOLC1/VASN/LDLRAD4/DDX17/EPB41L5/ADAM15/ZNF703/DLG5/PHLDB1/SFRP1/GLIPR2/MAD2L2/LRP6/FGF8/AXIN2/TGFB1/HAS2/PEF1/AMELX	42
BP	GO:1903364	positive regulation of cellular protein catabolic process	42/4749	140/18670	0.1265	0.3758	0.3057	RNF144A/AURKA/TRIB1/CBFA2T3/HSPA1A/PLK2/ECSCR/PLK1/DET1/LDLR/SMAD7/VCP/CLU/MAGEF1/HERPUD1/RNF40/SGTA/SMURF1/PIAS1/EZR/BCAP31/DVL1/LRP1/GBA/SUMO1/RNF19B/FMR1/RAD23A/EDEM2/USP5/GSK3A/UBQLN2/BAG2/SIRT2/ZFAND2A/RNF139/GCLC/NUPR1/OSBPL7/PSMD10/DNAJB2/TRIB3	42
BP	GO:0048013	ephrin receptor signaling pathway	27/4749	86/18670	0.1266	0.3758	0.3057	SIPA1L1/NTRK1/RAC1/EPHB1/MMP9/ACTG1/SRC/EPHB4/TIAM1/SDCBP/NTRK3/SDC2/PAK1/RBPJ/EFNB1/ARPC1B/PAK3/VAV2/ARPC5/SS18/AP2S1/CRK/CHN1/DNM1/CDC42/FYN/ACTB	27
BP	GO:0006195	purine nucleotide catabolic process	15/4749	44/18670	0.1271	0.376	0.3059	PDE4A/GPX1/ABCD1/NUDT16/NUDT1/PDE4D/PDE4B/HPRT1/PNP/SAMHD1/NUDT3/AMPD3/NT5E/PDE7B/NT5C2	15
BP	GO:0014003	oligodendrocyte development	15/4749	44/18670	0.1271	0.376	0.3059	CD9/ASCL1/GSN/PRDM8/FA2H/CLU/EIF2B3/TLR2/ERCC2/SOX11/B4GALT5/MED12/NKX6-2/TGFB1/HDAC10	15
BP	GO:0030225	macrophage differentiation	15/4749	44/18670	0.1271	0.376	0.3059	LIF/VEGFA/CSF2/CSF1R/TRIB1/SPI1/MMP9/CSF1/ZBTB46/PRKCA/TLR2/ADIPOQ/TGFB1/CDC42/SIRT1	15
BP	GO:0035850	epithelial cell differentiation involved in kidney development	15/4749	44/18670	0.1271	0.376	0.3059	LIF/NOTCH1/MYO1E/MMP9/WWTR1/PRKX/JAG1/BASP1/YAP1/ADIPOQ/CD34/STAT1/ACTA2/PDGFB/GATA3	15
BP	GO:0050654	chondroitin sulfate proteoglycan metabolic process	15/4749	44/18670	0.1271	0.376	0.3059	CHST15/CHPF2/IDS/B3GAT3/CSGALNACT1/IDUA/SLC35D1/B3GALT6/SPOCK3/CHST7/DSEL/CHPF/HEXB/CHST13/XYLT1	15
BP	GO:0070897	transcription preinitiation complex assembly	15/4749	44/18670	0.1271	0.376	0.3059	THRA/HMGB1/UBTF/WNT10B/SMARCB1/BRF2/SMARCA4/TAF6L/TAF11/TAF7/ESR1/TAF6/BDP1/BAZ2A/PSMC5	15
BP	GO:0090311	regulation of protein deacetylation	15/4749	44/18670	0.1271	0.376	0.3059	VEGFA/BCL6/SPRED2/ZNHIT1/SKI/FOXP3/PINK1/C6orf89/BEX4/CAMK2D/KDM5A/SPHK2/CTBP1/TGFB1/USP17L2	15
BP	GO:1903573	negative regulation of response to endoplasmic reticulum stress	15/4749	44/18670	0.1271	0.376	0.3059	HSPA5/HSPA1A/PTPN1/SYVN1/CLU/HERPUD1/UBXN1/SGTA/UBE2G2/PARK7/TXNDC12/BCL2L1/PPP1R15A/UBAC2/PDX1	15
BP	GO:0055072	iron ion homeostasis	25/4749	79/18670	0.1281	0.3786	0.308	TTC7A/ATP6V0D1/TFRC/TMPRSS6/STEAP3/FXN/HMOX1/ATP13A2/SRI/HEPH/NUBP1/ATP6V1A/SLC25A28/FTL/ACO1/NCOA4/EPAS1/FTH1/BDH2/ATP6V1G1/ISCU/HMOX2/CYBRD1/CCDC115/SLC40A1	25
BP	GO:0046822	regulation of nucleocytoplasmic transport	32/4749	104/18670	0.1282	0.3788	0.3082	IL1B/GTSE1/CAMK1/CDK5/YWHAE/RBM22/PTPN14/IWS1/SFN/NUP153/TCF7L2/SUPT6H/NOLC1/CHP1/PARK7/EMD/EFCAB7/CABP1/ECT2/ZC3H12A/BAG3/RAB23/UHMK1/CPSF6/RBM27/AAAS/NCBP2/TGFB1/PPP1R12A/MAPK1/NUP62/BARD1	32
BP	GO:0000731	DNA synthesis involved in DNA repair	17/4749	51/18670	0.1292	0.3805	0.3095	DTL/ISG15/TREX1/TRIM25/VCP/UBB/RFC2/NPLOC4/RPS27A/UBA52/POLD4/POLE/MAD2L2/POLN/WRN/POLE2/SIRT1	17
BP	GO:0007566	embryo implantation	17/4749	51/18670	0.1292	0.3805	0.3095	LIF/IL1B/PTGIS/SPP1/MMP9/RXRA/ARID1A/ACVR1C/TIMP1/RECK/RPL29/DDR1/BSG/C1QBP/PCSK5/PPARD/POLR1B	17
BP	GO:0030834	regulation of actin filament depolymerization	17/4749	51/18670	0.1292	0.3805	0.3095	CAPZB/GSN/SWAP70/TMOD2/CAPG/PDXP/ADD3/SPTBN1/TRIOBP/TWF2/CFL1/SPTAN1/CAPZA1/WDR1/VILL/SEMA5A/ADD2	17
BP	GO:0031103	axon regeneration	17/4749	51/18670	0.1292	0.3805	0.3095	PTPRF/KLF4/GRN/CNTF/SPP1/RGMA/TSPO/NTRK3/DHFR/SCARF1/LRP1/JUN/CTNNA1/PTPRS/MTR/NEFL/RTN4R	17
BP	GO:0048260	positive regulation of receptor-mediated endocytosis	17/4749	51/18670	0.1292	0.3805	0.3095	VEGFA/ANXA2P2/HIP1/SERPINE1/ANXA2/ARRB1/CLU/SFRP4/PPT1/HIP1R/PICK1/VTN/FMR1/ATAD1/IL4/LDLRAP1/NTF3	17
BP	GO:0072523	purine-containing compound catabolic process	17/4749	51/18670	0.1292	0.3805	0.3095	PDE4A/GPX1/ABCD1/NUDT16/NUDT1/PDE4D/PDE4B/HPRT1/PNP/ENPP4/DPYD/SAMHD1/NUDT3/AMPD3/NT5E/PDE7B/NT5C2	17
BP	GO:0032272	negative regulation of protein polymerization	23/4749	72/18670	0.1292	0.3805	0.3095	CAPZB/GSN/MYADM/TMOD2/CAPG/CLIP3/ADD3/PFN2/HIP1R/TMSB4Y/SPTBN1/STMN1/TRIOBP/TWF2/SPTAN1/MKKS/CAPZA1/TUBB4A/KANK3/TMSB15A/VILL/CDH5/ADD2	23
BP	GO:0035019	somatic stem cell population maintenance	23/4749	72/18670	0.1292	0.3805	0.3095	KLF4/SPI1/TP63/SKI/STAT3/RBPJ/PRDM16/ZFP36L2/SALL4/WNT7A/ZHX2/POLR2I/VPS72/POLR2C/YAP1/KLF10/SFRP1/POLR2J/PBX1/LBH/CUL4A/POLR2A/LDB1	23
BP	GO:0018105	peptidyl-serine phosphorylation	85/4749	299/18670	0.1297	0.3816	0.3104	LIF/AURKB/VEGFA/TTK/CDK1/WNK1/AURKA/NTRK2/RASSF2/TTBK1/CLSPN/DYRK3/CAMK1/CDK5/TNF/PLK2/AKT3/BAX/PLK1/MTOR/BCAR3/BAG4/MAST4/SMAD7/CCNB1/SRC/TENM1/MAPKAP1/PDE4D/ARRB1/CDK2/CAMK2A/MAPK12/NTRK3/PAK1/PFN2/PRKX/PINK1/PRKCA/DDIT4/PRKCI/DYRK4/MAST2/ULK1/BAK1/DRD1/ATP2B4/PLCL2/OSM/BDKRB2/PARK7/MKNK1/GGNBP2/SH2D3A/CD44/SH2D3C/PRKCE/GSK3A/BRSK2/CREBL2/BRAF/SGK2/EIF2AK3/CAMK2D/MAP4K1/ERN1/RIPK2/MAPKAPK2/UHMK1/STK32C/MAD2L2/PRKCB/PRKACB/ATR/CHEK2/STK38/NTF3/ATM/TGFB1/CSNK1G2/SBK1/MAPK1/PDGFB/PAK2/ILK	85
BP	GO:0030520	intracellular estrogen receptor signaling pathway	19/4749	58/18670	0.13	0.3818	0.3107	KANK2/CBFB/CYP7B1/TP63/SRC/PPARGC1B/TRIP4/PAK1/CARM1/ARID1A/DDX17/DDX54/YAP1/PADI2/TAF7/ESR1/DEFA1B/LBH/STRN3	19
BP	GO:0030837	negative regulation of actin filament polymerization	19/4749	58/18670	0.13	0.3818	0.3107	CAPZB/GSN/MYADM/TMOD2/CAPG/ADD3/PFN2/HIP1R/TMSB4Y/SPTBN1/TRIOBP/TWF2/SPTAN1/MKKS/CAPZA1/KANK3/TMSB15A/VILL/ADD2	19
BP	GO:0051058	negative regulation of small GTPase mediated signal transduction	19/4749	58/18670	0.13	0.3818	0.3107	ITGA3/BCL6/TIMP2/STAMBP/TNFAIP1/MAPKAP1/ARHGAP35/STMN3/STMN1/RASA3/CCDC125/RAPGEF1/RASA4/RABGEF1/RASAL1/CD2AP/KCTD13/LZTR1/NUP62	19
BP	GO:0098930	axonal transport	19/4749	58/18670	0.13	0.3818	0.3107	KIF4A/KIF1C/BLOC1S6/BLOC1S1/CNIH2/BLOC1S4/AP3D1/DTNBP1/FMR1/AP3M2/SNAPIN/MAP1A/NEFL/AP3B2/UCHL1/SPG7/SYBU/MGARP/TERF2	19
BP	GO:0032231	regulation of actin filament bundle assembly	30/4749	97/18670	0.1305	0.3829	0.3115	SDC4/RAC1/NF2/FHOD1/MTOR/BAG4/SWAP70/ARHGEF5/PTGER4/TGFB3/PAK1/PFN2/S1PR1/STMN1/CLASP2/CD47/LIMCH1/S100A10/MKKS/ARAP1/LIMK1/SH3PXD2B/ALMS1/SFRP1/TPM1/SORBS3/WASF2/ID1/CDC42/WAS	30
BP	GO:0060996	dendritic spine development	30/4749	97/18670	0.1305	0.3829	0.3115	SIPA1L1/EPHB1/CAMK1/CDK5/LRP8/SRGAP2/PLK2/MTOR/TIAM1/PAK4/CAMK2A/PAK3/CFL1/DVL1/WNT7A/FMR1/UBE3A/ARHGAP33/ACSL4/ARF4/DLG5/PTPRS/ARF6/LLPH/CDC42/UBA6/SLC12A5/DLG4/PAK2/SLC9A6	30
BP	GO:0007179	transforming growth factor beta receptor signaling pathway	58/4749	199/18670	0.1307	0.3833	0.3118	SKIL/FURIN/CD109/ITGA3/CDKN2B/LRG1/PMEPA1/ZYX/SNX25/TGFB1I1/PML/HSPA5/ARHGEF18/HSPA1A/SKI/USP9X/DAND5/SMAD7/SRC/NKX2-1/SDCBP/UBB/TGFB3/ZFYVE9/PRDM16/SMAD6/RPS27A/SMURF1/FAM89B/UBA52/DUSP22/LEMD3/VASN/LDLRAD4/JUN/ACVR1C/ACVR2B/TAB1/EID2/CITED2/SOX11/ZNF703/HTRA4/SMAD1/LEFTY1/HPGD/PARD6A/FOS/HTRA1/ID1/TGFB1/ZNF451/ADAM9/CDH5/VEPH1/MIR17HG/LRRC32/SIRT1	58
BP	GO:0071824	protein-DNA complex subunit organization	82/4749	288/18670	0.131	0.3833	0.3118	CENPF/CENPA/HJURP/ASF1B/CDT1/CENPM/CHAF1A/MCM4/MCM5/PTMA/CHAF1B/GMNN/THRA/CENPW/ZNHIT1/DDB2/HMGB1/UBTF/SPTY2D1/NASP/WNT10B/RAD51/SMARCB1/NAP1L2/MCM2/CENPE/CDC45/CENPT/DMC1/UBB/CENPO/RPS27A/MCM7/BRF2/TERF1/CDK7/RPL23/SMARCA4/PIAS1/RAD23B/UBA52/NAP1L3/SUPT6H/CENPI/TAF6L/RNF8/CENPP/CENPN/UBN1/ARID1A/ERCC5/MCM3/ERCC2/TAF11/VPS72/GTF2H2/TSPYL1/GTF2H1/HELLS/OIP5/TSPYL4/TAF7/KAT6B/ESR1/TAF6/BDP1/MNAT1/CETN2/CENPV/BAZ2A/RAD52/NAP1L5/GTF2H5/XPA/SENP6/POGZ/CUL4A/TRAPPC12/ASF1A/PSMC5/KAT6A/CENPK	82
BP	GO:0006475	internal protein amino acid acetylation	49/4749	166/18670	0.1313	0.3833	0.3118	TWIST1/LIF/IL1B/GTF3C4/IRF4/SPI1/DPF3/BRCA2/PHF10/FOXP3/SMARCB1/CRTC2/ING3/NAP1L2/ING5/KANSL3/IWS1/ARRB1/MORF4L2/KANSL1L/KAT2A/ACTL6A/MDH2/TAF1L/YEATS4/SUPT3H/TAF9B/MUC1/TAF6L/TAF10/CHEK1/MCRS1/BRPF3/TAF7/KAT6B/POR/DPF1/TADA2A/SPHK2/CTBP1/TGFB1/ZNF451/TRIM16/LDB1/GATA3/CPA4/TADA1/KAT6A/SIRT1	49
BP	GO:0048469	cell maturation	52/4749	177/18670	0.1313	0.3833	0.3118	KIF14/VEGFA/IL21/CDKN1A/PPARG/KLF2/AURKA/BCL11A/TRIP13/CBFB/CLEC7A/C1QL1/PPP2R1A/TYMS/ASCL1/BRCA2/MTOR/CCR6/CCNB1/FBXO5/PABPC1L/BTK/DMC1/AXL/FAM20C/RUNX2/PICK1/TBX6/SCARF1/ELSPBP1/FEM1B/SLC26A6/MAEA/SOX8/ERCC2/REC8/EPAS1/IRX5/PAEP/BFSP2/B4GALT5/SIRT2/PCSK4/C1QA/TDRD5/FZD5/CATSPER2/LHX6/POU2F2/CDC25B/GATA3/RAC3	52
BP	GO:0002183	cytoplasmic translational initiation	12/4749	34/18670	0.1317	0.3833	0.3118	TICRR/EIF4EBP1/MTOR/EIF3I/EIF4H/EIF3L/EIF3H/EIF2D/EIF2S3/EIF3G/DENR/EIF3E	12
BP	GO:0032148	activation of protein kinase B activity	12/4749	34/18670	0.1317	0.3833	0.3118	IL18/ADRA2B/MTOR/SRC/MAPKAP1/NTRK3/PINK1/PARK7/INSR/NTF3/PDGFB/MLST8	12
BP	GO:0032660	regulation of interleukin-17 production	12/4749	34/18670	0.1317	0.3833	0.3118	IL18/IL21/TNFSF4/TLR4/FOXP3/LY9/NOD2/IL27RA/OSM/PRNP/TGFB1/IL23A	12
BP	GO:0043276	anoikis	12/4749	34/18670	0.1317	0.3833	0.3118	NOTCH1/NTRK2/DAPK2/MCL1/E2F1/MTOR/SRC/BMF/CEACAM5/ZNF304/MYBBP1A/CHEK2	12
BP	GO:0045920	negative regulation of exocytosis	12/4749	34/18670	0.1317	0.3833	0.3118	NOTCH1/CEACAM1/LGALS9/CCR2/HMOX1/SYT4/RSC1A1/GNAI2/FMR1/RABGEF1/BCR/TRIM9	12
BP	GO:0071868	cellular response to monoamine stimulus	12/4749	34/18670	0.1317	0.3833	0.3118	NR4A3/PDE4D/PDE4B/ADCY6/ATF4/DRD1/ATP2B4/GABPA/SIRT2/ADIPOQ/ID1/MAPK1	12
BP	GO:0071870	cellular response to catecholamine stimulus	12/4749	34/18670	0.1317	0.3833	0.3118	NR4A3/PDE4D/PDE4B/ADCY6/ATF4/DRD1/ATP2B4/GABPA/SIRT2/ADIPOQ/ID1/MAPK1	12
BP	GO:0097009	energy homeostasis	12/4749	34/18670	0.1317	0.3833	0.3118	NR4A3/STAT3/UBB/CRTC1/FOXO1/PRCP/AMPD2/AMPD3/ACACB/DLL1/METRNL/OMA1	12
BP	GO:0002407	dendritic cell chemotaxis	9/4749	24/18670	0.1319	0.3833	0.3118	CCR1/LGALS9/HMGB1/CCR6/CCR2/ARHGEF5/CCR5/TRPM4/C1QBP	9
BP	GO:0002861	regulation of inflammatory response to antigenic stimulus	9/4749	24/18670	0.1319	0.3833	0.3118	IL10/TNF/GPX1/BTK/HLA-E/LTA/CNR1/PARK7/PSMB4	9
BP	GO:0008535	respiratory chain complex IV assembly	9/4749	24/18670	0.1319	0.3833	0.3118	SCO2/COX17/PET117/COX18/COA3/SCO1/FASTKD3/COA5/COA4	9
BP	GO:0009309	amine biosynthetic process	9/4749	24/18670	0.1319	0.3833	0.3118	SMOX/SMS/MOXD1/SAT1/OAZ3/OAZ2/TPH1/AANAT/OAZ1	9
BP	GO:0032878	regulation of establishment or maintenance of cell polarity	9/4749	24/18670	0.1319	0.3833	0.3118	KIF20B/GSN/DOCK8/WDPCP/KRIT1/RUFY3/BCAS3/CDH5/GATA3	9
BP	GO:0035588	G protein-coupled purinergic receptor signaling pathway	9/4749	24/18670	0.1319	0.3833	0.3118	ACPP/ADORA2A/P2RY13/P2RY11/GPR34/P2RY10/GNAI2/P2RY1/PTAFR	9
BP	GO:0046475	glycerophospholipid catabolic process	9/4749	24/18670	0.1319	0.3833	0.3118	ABHD16A/LDLR/GDPD3/GDPD1/PLA2G15/PNPLA6/PRDX6/GDE1/GPCPD1	9
BP	GO:0051446	positive regulation of meiotic cell cycle	9/4749	24/18670	0.1319	0.3833	0.3118	CDC25A/UBE2B/CDC25C/MSX1/SIRT2/ANKRD31/INSR/PLCB1/CDC25B	9
BP	GO:0090023	positive regulation of neutrophil chemotaxis	9/4749	24/18670	0.1319	0.3833	0.3118	RAC1/TIRAP/DAPK2/CD74/C3AR1/RAC2/C1QBP/THBS4/IL23A	9
BP	GO:1900078	positive regulation of cellular response to insulin stimulus	9/4749	24/18670	0.1319	0.3833	0.3118	ESRRA/SORL1/SRC/PAK1/ADIPOR1/GNAI2/NUCKS1/GKAP1/SIRT1	9
BP	GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	38/4749	126/18670	0.1324	0.3844	0.3127	SKIL/CD109/NOTCH1/PMEPA1/SNX25/TGFB1I1/HSPA5/HSPA1A/SKI/TMPRSS6/DAND5/SMAD7/SORL1/NKX2-1/GREM2/UBB/TGFB3/PRDM16/SMAD6/RPS27A/SMURF1/FAM89B/UBA52/LEMD3/VASN/LDLRAD4/RBPMS2/EID2/HTRA4/DACT2/SFRP1/CER1/HTRA1/TGFB1/ZNF451/VEPH1/MIR17HG/SIRT1	38
BP	GO:0016042	lipid catabolic process	94/4749	333/18670	0.1325	0.3845	0.3128	TWIST1/IL1B/HSD3B7/NAGA/NEU4/YWHAH/PLCD3/SPP1/THRA/PLD4/TNF/PDXDC1/ABHD16A/GM2A/PLBD1/NEU1/MTOR/ADTRP/LDLR/ABCD1/GDPD3/SORL1/MECR/ABCD2/AIG1/FABP5/SLC27A2/PLA2G12A/MCAT/PPT1/GLYATL2/ACOX2/CYP26C1/GDPD1/TYSND1/ACOT8/HSD17B14/SCARF1/LRP1/GBA/CNR1/AMACR/CES3/CYP27B1/ETFA/PEX2/ACER1/PRKCE/ACER2/BDH2/PLA2G15/PNPLA6/ASAH2/RARRES2/ABHD1/PRDX6/SIRT2/LIPK/CYP4F12/ADIPOQ/CPT1A/BSCL2/PLA2G2A/GDE1/PLA2G2C/ASAH2B/SLC27A4/NEU3/MGST2/ACACB/ETFB/GALC/PCCB/ACAD11/HEXB/ECI1/LIPA/NUDT19/PLA2G5/PECR/FUCA1/PPARD/PAFAH1B3/CYP7A1/GPCPD1/PLCB1/PEX13/HADHB/PLB1/FABP12/SESN2/HINT2/LPIN1/DECR2	94
BP	GO:0045637	regulation of myeloid cell differentiation	72/4749	251/18670	0.1325	0.3845	0.3128	LIF/IRF7/HMGB3/CSF2/NR4A3/TRIB1/FES/RASSF2/ISG15/IL17A/SPI1/CSF3R/CBFB/CCR1/LGALS3/CEACAM1/TNF/CSF1/ZFP36/HSPA1A/TLR4/PIAS3/MTOR/ESRRA/STAT3/ZBTB46/PPARGC1B/TFE3/HSPA9/LILRB4/GNAS/CCL3/TNRC6B/CD74/JAG1/PRKCA/JUN/TOB2/NFKBIA/CA2/CEBPB/KLF10/IL20/BGLAP/SFRP1/GABPA/ADIPOQ/P4HTM/IL4/TYROBP/ITGA2B/PURB/ZFP36L1/TESC/PRKCB/TRAF6/STAT1/TNFSF11/FOS/DLL1/SLC9B2/ZNF675/TGFB1/TMEM64/CUL4A/POU4F1/RARA/ZFPM1/LDB1/TCTA/NME2/IL23A	72
BP	GO:0032651	regulation of interleukin-1 beta production	28/4749	90/18670	0.1326	0.3845	0.3128	EGR1/NLRP3/ACP5/TLR8/HK1/SIRPA/CLEC7A/LGALS9/PML/HMGB1/TLR4/LILRA2/CCL3/CD33/NOD2/MNDA/ZC3H12A/LILRA5/IFI16/GHRL/RIPK2/F2R/TYROBP/CARD8/FZD5/TRIM16/P2RX7/CX3CR1	28
BP	GO:0034333	adherens junction assembly	28/4749	90/18670	0.1326	0.3845	0.3128	VEGFA/SDC4/ITGA2/RAC1/CORO1C/CTTN/SMAD7/SRC/TRIP6/LIMS1/CLASP2/WDPCP/LIMCH1/DUSP22/S100A10/LRP1/THY1/EPB41L5/ZNF703/DLG5/SFRP1/BCR/WHAMM/PIP5K1A/BCAS3/FMN1/LAMA5/LDB1	28
BP	GO:0018209	peptidyl-serine modification	91/4749	322/18670	0.1341	0.3885	0.316	LIF/AURKB/VEGFA/TTK/CDK1/WNK1/AURKA/NTRK2/RASSF2/TTBK1/CLSPN/DYRK3/CAMK1/CDK5/GALNT2/TNF/PLK2/AKT3/BAX/PLK1/MTOR/BCAR3/BAG4/MAST4/SMAD7/CCNB1/SRC/TENM1/PARP2/MAPKAP1/PDE4D/ARRB1/CDK2/CAMK2A/MAPK12/NTRK3/PAK1/PFN2/MGAT5B/PRKX/GALNT1/PINK1/PRKCA/DDIT4/PRKCI/SPOCK3/DYRK4/MAST2/ULK1/BAK1/DRD1/ATP2B4/PLCL2/OSM/BDKRB2/PARK7/MKNK1/GGNBP2/SH2D3A/CD44/SH2D3C/PRKCE/POGLUT1/GSK3A/BRSK2/CREBL2/BRAF/SGK2/EIF2AK3/CAMK2D/MAP4K1/ERN1/RIPK2/MAPKAPK2/UHMK1/STK32C/MAD2L2/PRKCB/PRKACB/ATR/CHEK2/STK38/NTF3/ATM/TGFB1/CSNK1G2/SBK1/MAPK1/PDGFB/PAK2/ILK	91
BP	GO:0042509	regulation of tyrosine phosphorylation of STAT protein	26/4749	83/18670	0.1346	0.3899	0.3172	LIF/IL18/CSF2/IL21/CSF1R/TNFRSF18/CNTF/NF2/PPP2R1A/TNF/STAT3/PARP14/SOCS3/FLT3/PTK6/PPP2CA/OSM/GGNBP2/PIBF1/CNOT7/IL13/IL20/IL4/ARL2BP/FYN/IL23A	26
BP	GO:0006022	aminoglycan metabolic process	50/4749	170/18670	0.1347	0.3899	0.3172	IL1B/B3GNT5/SDC4/HS3ST3B1/HS3ST3A1/CHST15/GLB1/HPSE/GPC1/CHPF2/HYAL3/IDS/PIM1/B3GAT3/OGN/CSGALNACT1/IDUA/SDC2/SLC35D2/SLC35D1/ITIH3/SDC1/OVGP1/PGLYRP3/B3GALT6/B3GNT2/SPOCK3/CHST7/EXT1/EXTL2/CHP1/GPC2/CD44/DSEL/ST3GAL3/HS6ST1/HAS3/CHPF/B4GALT5/HEXB/GUSB/CHST13/FUCA1/XYLT1/ITIH6/TGFB1/HAS2/PDGFB/B4GALT4/B4GALT7	50
BP	GO:0045927	positive regulation of growth	77/4749	270/18670	0.1359	0.3923	0.3192	HBEGF/VEGFA/NOTCH1/CDK1/SRF/CYFIP1/BBS2/TNFRSF12A/CSF1/SEMA7A/BRAT1/MTOR/ZFYVE27/PIM1/FXN/CCNB1/PARP2/FGFR1OP/SFN/SYT4/PLS1/SDCBP/NTRK3/PAK1/CPNE5/FGF9/RBPJ/HLX/SMURF1/EZR/N6AMT1/TWF2/L1CAM/RFTN1/CXCL16/TAF9B/MKKS/LRP1/LIMK1/CACNA2D2/BASP1/SH3PXD2B/ERBB2/EXOSC2/ZNF639/IST1/CYBA/YAP1/IL7/RASAL1/CDKN2AIP/SFRP1/GHRL/S100A8/GPR21/SERP1/ACACB/SEMA4D/INSR/BMP10/KLHL22/FGF8/DLL1/PPARD/PSMD10/RAG2/PLCB1/RUFY3/SEMA5A/CDC42/ADNP/MAPK1/TRPC5/MIR17HG/GDI1/EXOSC9/ILK	77
BP	GO:0006458	'de novo' protein folding	14/4749	41/18670	0.136	0.3923	0.3192	HSPA2/HSPA5/HSPA1A/DNAJB5/ENTPD5/HSPA9/DNAJB12/CD74/FKBP1A/HSPA6/HSPA1L/HSPA14/DNAJB4/CHCHD4	14
BP	GO:0010955	negative regulation of protein processing	14/4749	41/18670	0.136	0.3923	0.3192	CHAC1/NOL3/SERPINE1/IL1R2/A2M/BCL2L12/CTSZ/SNX12/BIRC3/SERPING1/PRNP/BIRC7/CARD8/USP17L2	14
BP	GO:0030890	positive regulation of B cell proliferation	14/4749	41/18670	0.136	0.3923	0.3192	IL21/CDKN1A/BCL6/TIRAP/TFRC/TNFRSF4/TLR4/CD74/PTPRC/IL7/IL13/CARD11/IL4/SLC39A10	14
BP	GO:0035337	fatty-acyl-CoA metabolic process	14/4749	41/18670	0.136	0.3923	0.3192	SLC25A1/TECR/ABCD1/THEM5/SCD/FAR2/PPT1/ACSL1/HSD17B8/ELOVL7/ELOVL1/ACSL4/DGAT2/FASN	14
BP	GO:0090317	negative regulation of intracellular protein transport	14/4749	41/18670	0.136	0.3923	0.3192	CDK5/BAG4/UBE2G2/INSIG1/CHP1/PARK7/CABP1/BAG3/RAB23/ADIPOQ/UBAC2/GDI1/USP17L2/BARD1	14
BP	GO:0150077	regulation of neuroinflammatory response	14/4749	41/18670	0.136	0.3923	0.3192	IL1B/IL18/TTBK1/GRN/MMP9/TNF/CD200/LDLR/CCL3/PTPRC/IL4/TNFRSF1B/NUPR1/ATM	14
BP	GO:1903318	negative regulation of protein maturation	14/4749	41/18670	0.136	0.3923	0.3192	CHAC1/NOL3/SERPINE1/IL1R2/A2M/BCL2L12/CTSZ/SNX12/BIRC3/SERPING1/PRNP/BIRC7/CARD8/USP17L2	14
BP	GO:0016049	cell growth	134/4749	484/18670	0.1363	0.393	0.3198	RASGRP2/HBEGF/GNG4/KIF14/VEGFA/CDKN1A/PPARG/AURKA/SRF/BCL11A/IGFBP4/BCL6/CYFIP1/CDK5/ENO1/CEACAM1/SPP1/PPP2R1A/PML/SOCS2/SEMA4C/TNFRSF12A/SIRT6/SEMA7A/ING1/HSPA1A/CTTN/USP9X/CDKN2C/BRAT1/MTOR/NAIF1/ZFYVE27/PSRC1/MSX1/SEMA3G/FXN/CYFIP2/PARP2/FGFR1OP/TIAM1/SFN/TMC8/SYT4/SEMA6C/PAK4/SDCBP/BST2/NTRK3/PLXNA1/PPT1/PAK1/URI1/BAP1/CPNE5/IGFBP3/SEMA6B/NUBP1/SMURF1/SMARCA4/FGF13/N6AMT1/ARHGAP4/TWF2/L1CAM/ADIPOR2/CXCL16/DVL1/ULK1/PPP2CA/TAF9B/CDKN2A/LRP1/ADIPOR1/LIMK1/TTL/EBAG9/CYP27B1/SH3BP4/EPB41L5/ATAD3A/ERBB2/EXOSC2/ZNF639/NDN/SEMA3B/IST1/CYBA/ADAM15/DDR1/MAP2K4/SEMA5B/GSK3A/RASAL1/CDKN2AIP/SFRP1/SGK2/S100A8/CAMK2D/CRLF3/PTPRS/DCBLD2/MAD2L2/SEMA4D/LAMTOR2/BMP10/KLHL22/CLSTN3/SPHK2/EAF2/AKAP13/LLPH/IP6K2/PPP1R9B/PPARD/RAPH1/PSMD10/RUFY3/TGFB1/SEMA5A/CDC42/NET1/NDUFA13/RTN4R/ADNP/DNAJB2/TRPC5/SESN2/GDI1/EXOSC9/OSGIN2/ILK/SLC9A6/SIRT1	134
BP	GO:0016358	dendrite development	67/4749	233/18670	0.1372	0.3953	0.3216	MAP6/SIPA1L1/BCL11A/CDC20/EPHB1/CYFIP1/LZTS1/YWHAH/CAMK1/CDK5/GORASP1/LRP8/SRGAP2/PLK2/MTOR/CUX1/TIAM1/PAK4/CAMK2A/SDC2/HPRT1/CRTC1/PAK3/PREX1/FBXO31/LRP4/CARM1/TMEM106B/CFL1/EZH2/SCARF1/DVL1/DTNBP1/WNT7A/FMR1/UBE3A/MAP1S/CRK/ARHGAP33/MINK1/CD3E/GSK3A/ACSL4/RAPGEF2/ARF4/DLG5/GHRL/SLITRK5/PARP6/PTPRS/TRAPPC4/CHRNA3/PACSIN1/SEMA4D/MAP1A/ARF6/LLPH/ID1/CDC42/UBA6/TRPC5/SLC12A5/FYN/DLG4/PAK2/ILK/SLC9A6	67
BP	GO:0070372	regulation of ERK1 and ERK2 cascade	85/4749	300/18670	0.1372	0.3953	0.3216	LIF/IL1B/NOTCH1/FAM83D/ICAM1/DUSP10/DUSP4/CSF1R/CCL20/NTRK1/KLF4/PDGFA/CCL3L3/PTPN6/EPHB1/DUSP6/SIRPA/CCL22/TIRAP/CCR1/GPNMB/CEACAM1/LGALS9/ATF3/HMGB1/TNF/SEMA7A/TLR4/CHRNA10/BTN2A2/PTPN1/TRAF7/SRC/TIAM1/CFLAR/SCIMP/ARRB1/HTR2A/CCL3/HAVCR2/CD74/FLT3/CCL2/SYNJ2BP/CCL17/CASR/PTPRC/EZR/PRKCA/CCL18/NOD2/LRP1/NDRG2/IL26/FLT1/SIRT3/GNAI2/RAPGEF1/FPR2/JUN/ERBB2/CD44/C3orf33/FLT4/RAPGEF2/BRAF/ADIPOQ/GLIPR2/PLA2G2A/RIPK2/F2R/TIMP3/P2RY1/CCL23/FGF8/TNFAIP8L3/TNFSF11/CCL7/PLA2G5/DDT/TGFB1/CCL15/PDGFB/SHC1/DUSP1	85
BP	GO:0055008	cardiac muscle tissue morphogenesis	22/4749	69/18670	0.1378	0.3966	0.3227	NOTCH1/SIRT6/MYLK2/SMAD7/RBPJ/S1PR1/COL11A1/MYBPC3/FKBP1A/RXRA/XIRP2/MYH7/TNNC1/MYOM1/BMP10/TPM1/MYH6/TGFB1/TCAP/POU4F1/MYBPC2/ZFPM1	22
BP	GO:0045931	positive regulation of mitotic cell cycle	48/4749	163/18670	0.1382	0.3969	0.3229	ESPL1/IL1B/CDCA5/UBE2C/CDK1/CDT1/DTL/AURKA/HSPA2/KIF20B/DLGAP5/NUSAP1/CDC25A/CDC6/EIF4EBP1/BRCA2/CDC25C/WNT10B/CCNB1/FBXO5/NUMA1/NDC80/DBF4B/CDC45/ASNS/PHIP/PRKCA/AIF1/BRD4/CDK10/TTL/ANAPC11/XRCC3/NSFL1C/INSR/FGF8/PBX1/MTA3/ADAMTS1/ANKRD17/SMC5/PLCB1/TGFB1/CUL4A/CDC25B/CCND1/PDGFB/NUP62	48
BP	GO:0051170	import into nucleus	48/4749	163/18670	0.1382	0.3969	0.3229	TXNIP/CDKN1A/RBM22/PML/KPNA2/NUP98/RGPD2/HTATIP2/MMP12/LMNA/STAT3/CSE1L/FGF9/NUP153/TMCO6/RPL23/DRD1/NUP88/NOLC1/RANBP6/FAM53B/CHP1/EFCAB7/KPNA3/NFKBIA/CABP1/POM121C/ECT2/DDX20/ARNTL/NUP50/ZC3H12A/BAG3/SNRPB/FAM53A/RAB23/POM121L2/SNRPD2/SNUPN/NUP93/NUP35/SMN1/TGFB1/RGPD1/MAPK1/GEMIN5/NUP62/TNPO1	48
BP	GO:0007140	male meiotic nuclear division	16/4749	48/18670	0.1382	0.3969	0.3229	HSPA2/TRIP13/KIF18A/SLC2A8/BRCA2/TDRD9/DMC1/UBB/TAF1L/FIGNL1/REC8/UBR2/DMRTC2/ASZ1/ATM/MLH3	16
BP	GO:0009069	serine family amino acid metabolic process	16/4749	48/18670	0.1382	0.3969	0.3229	SERINC3/SDS/MPST/TST/GGT1/GLDC/CTH/GCAT/MRI1/MTHFD1/SEPHS1/MTRR/PSPH/ENOPH1/GCLC/AMT	16
BP	GO:0061014	positive regulation of mRNA catabolic process	16/4749	48/18670	0.1382	0.3969	0.3229	ZFP36/ZC3H12D/PLEKHN1/TNRC6B/UPF1/ZFP36L2/MEX3D/RBM23/ZC3H12A/CNOT7/YTHDF3/METTL16/GIGYF2/ZC3HAV1/ZFP36L1/KHSRP	16
BP	GO:0042180	cellular ketone metabolic process	71/4749	248/18670	0.1385	0.3978	0.3236	EGR1/TWIST1/IL1B/NR4A3/PPARG/TPI1/PDPR/TREX1/CEACAM1/KDSR/FDXR/PPTC7/MTOR/ABCD1/ABCD2/PSMD8/ATCAY/FABP5/PSMD1/PSMD2/CD74/CRYZL1/PSMF1/TYSND1/NQO1/NMT1/PRKAB2/OAZ3/ADIPOR2/OXCT1/BHMT/SLC45A3/INSIG1/PSMD9/ATP2B4/ADIPOR1/PSMA5/PRKAG2/CNR1/PARK7/PSMB7/OAZ2/PIBF1/PRKCE/PSMD5/IDO1/PSME2/NDUFA9/ADM/ADIPOQ/CPT1A/PSMB5/DGAT2/COQ10A/ACACB/PSMB4/PSMA3/OAZ1/CYP11A1/CYP7A1/PSMD10/PSMB1/PSMD7/PSMB3/RDH10/GSTZ1/PSMC5/AKR1A1/TRIB3/PSMD11/SIRT1	71
BP	GO:0002886	regulation of myeloid leukocyte mediated immunity	18/4749	55/18670	0.1389	0.3981	0.3239	FES/LGALS9/GAB2/IL4R/CCR2/HMOX1/BTK/CD177/HLA-E/ARG1/UNC13D/RAC2/RABGEF1/IL13/FER/SPHK2/BCR/PTAFR	18
BP	GO:0032781	positive regulation of ATPase activity	18/4749	55/18670	0.1389	0.3981	0.3239	HSPA2/UHRF1/DNAJA1/ATP2A1/AHSA1/PFN2/ATP1B1/CASR/MYBPC3/SUMO1/NCAPH/ATP1B3/DNAJB6/DNAJC24/TPM1/DNAJB4/ALDOB/DNAJB2	18
BP	GO:0043551	regulation of phosphatidylinositol 3-kinase activity	18/4749	55/18670	0.1389	0.3981	0.3239	KLF4/SOCS2/SRC/SOCS3/AMBRA1/PIK3R5/FLT3/VAV2/NOD2/SLA2/CD19/FLT1/FPR2/AGAP2/PIK3R4/TNFAIP8L3/TGFB1/PDGFB	18
BP	GO:0043954	cellular component maintenance	18/4749	55/18670	0.1389	0.3981	0.3239	ITGA3/CSF1R/C1QL1/CTTN/HOMER1/IGF1R/CD177/PLEKHA7/PICK1/SUPT6H/TANC1/ERC2/PRNP/F2R/INSR/ARF6/PARD6A/FYN	18
BP	GO:0002438	acute inflammatory response to antigenic stimulus	8/4749	21/18670	0.1403	0.4004	0.3258	ICAM1/BTK/HLA-E/CNR1/PARK7/CD6/NPFF/GATA3	8
BP	GO:0003094	glomerular filtration	8/4749	21/18670	0.1403	0.4004	0.3258	MCAM/SULF2/MYO1E/CD34/F2R/PDGFB/XPNPEP3/GJA5	8
BP	GO:0007035	vacuolar acidification	8/4749	21/18670	0.1403	0.4004	0.3258	GRN/ATP6V0D1/PPT1/ROGDI/SNAPIN/DMXL1/DMXL2/CCDC115	8
BP	GO:0010829	negative regulation of glucose transmembrane transport	8/4749	21/18670	0.1403	0.4004	0.3258	IL1B/TNF/SIRT6/PEA15/FABP5/RSC1A1/GSK3A/PRKCB	8
BP	GO:0035455	response to interferon-alpha	8/4749	21/18670	0.1403	0.4004	0.3258	IFITM2/BST2/IFIT3/AXL/IFITM3/IFITM1/IFIT2/GATA3	8
BP	GO:0042438	melanin biosynthetic process	8/4749	21/18670	0.1403	0.4004	0.3258	TRPC1/CTNS/MYO5A/ASIP/OCA2/RAPGEF2/DDT/TYRP1	8
BP	GO:0045061	thymic T cell selection	8/4749	21/18670	0.1403	0.4004	0.3258	JAG2/SRF/CD74/PTPRC/CD3E/CARD11/ZAP70/GATA3	8
BP	GO:0048245	eosinophil chemotaxis	8/4749	21/18670	0.1403	0.4004	0.3258	CCL22/DAPK2/LGALS3/CCL3/CCL2/CCL23/CCL7/CCL15	8
BP	GO:0060972	left/right pattern formation	8/4749	21/18670	0.1403	0.4004	0.3258	NOTCH1/SNAI1/IFT122/IFT172/EPB41L5/CITED2/SETDB2/DLL1	8
BP	GO:2000678	negative regulation of transcription regulatory region DNA binding	8/4749	21/18670	0.1403	0.4004	0.3258	MSX1/SRI/ENHO/PER2/DDIT3/SOX11/MAD2L2/ZNF675	8
BP	GO:0006363	termination of RNA polymerase I transcription	11/4749	31/18670	0.1409	0.4006	0.3259	UBTF/CDK7/ERCC2/GTF2H2/GTF2H1/TAF1A/ZNRD1/MNAT1/TAF1D/GTF2H5/POLR1B	11
BP	GO:0006506	GPI anchor biosynthetic process	11/4749	31/18670	0.1409	0.4006	0.3259	PIGK/PIGH/DPM2/PIGQ/PIGO/PIGC/PIGW/PIGM/PIGA/PIGG/PIGT	11
BP	GO:0010458	exit from mitosis	11/4749	31/18670	0.1409	0.4006	0.3259	ANLN/CDCA5/UBE2C/UBE2S/CLASP2/SIRT2/CDC14B/CHMP2A/PPP1R9B/SIRT7/TGFB1	11
BP	GO:0043304	regulation of mast cell degranulation	11/4749	31/18670	0.1409	0.4006	0.3259	FES/LGALS9/GAB2/IL4R/HMOX1/UNC13D/RAC2/RABGEF1/IL13/FER/SPHK2	11
BP	GO:0044319	wound healing, spreading of cells	11/4749	31/18670	0.1409	0.4006	0.3259	HBEGF/COL5A1/CEACAM1/MTOR/MMP12/ARHGAP35/CLASP2/WNT7A/CD44/CD151/DDR1	11
BP	GO:0090505	epiboly involved in wound healing	11/4749	31/18670	0.1409	0.4006	0.3259	HBEGF/COL5A1/CEACAM1/MTOR/MMP12/ARHGAP35/CLASP2/WNT7A/CD44/CD151/DDR1	11
BP	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	11/4749	31/18670	0.1409	0.4006	0.3259	ZNF385A/SNAI1/CLU/CD74/BID/TAF9B/MUC1/BCL2L12/CD44/BCL2L1/SIRT1	11
BP	GO:1903319	positive regulation of protein maturation	11/4749	31/18670	0.1409	0.4006	0.3259	IL1B/ENO1/GSN/TIMM17A/ASTL/SRC/SPON1/KLKB1/BAG2/MYH9/C6	11
BP	GO:0006637	acyl-CoA metabolic process	32/4749	105/18670	0.1413	0.4011	0.3263	PDPR/ACSM3/ACOT11/SLC25A1/TECR/ABCD1/THEM5/PMVK/SCD/FAR2/OGDH/PDHB/ACBD6/PPT1/HMGCL/ACSL1/PDHX/HSD17B8/ACOT8/DLST/DLAT/ELOVL7/ELOVL1/ACSL4/OXSM/DGAT2/ACACB/ACSS1/FASN/MPC1/ACOT6/GSTZ1	32
BP	GO:0032006	regulation of TOR signaling	32/4749	105/18670	0.1413	0.4011	0.3263	FAM83D/SEC13/DYRK3/RFFL/AKT3/ITFG2/TTI1/SIK3/WDR24/C12orf66/DDIT4/GBA/SLC38A9/SH3BP4/DEPTOR/ARNTL/GSK3A/HTR6/NPRL3/FBXO9/UBR2/LAMTOR4/LAMTOR2/KLHL22/TBCK/ATM/RRAGB/SESN2/SEH1L/MLST8/SIRT1/NPRL2	32
BP	GO:0035383	thioester metabolic process	32/4749	105/18670	0.1413	0.4011	0.3263	PDPR/ACSM3/ACOT11/SLC25A1/TECR/ABCD1/THEM5/PMVK/SCD/FAR2/OGDH/PDHB/ACBD6/PPT1/HMGCL/ACSL1/PDHX/HSD17B8/ACOT8/DLST/DLAT/ELOVL7/ELOVL1/ACSL4/OXSM/DGAT2/ACACB/ACSS1/FASN/MPC1/ACOT6/GSTZ1	32
BP	GO:0043462	regulation of ATPase activity	25/4749	80/18670	0.1432	0.4063	0.3306	PPIF/HSPA2/UHRF1/DNAJA1/ATP2A1/AHSA1/PFN2/ATP1B1/CASR/TPM2/MYBPC3/SUMO1/NCAPH/ATP1B3/TNNC1/BRSK2/DNAJB6/DNAJC24/PAM16/TPM1/DNAJB4/ALDOB/MYH6/TMEM64/DNAJB2	25
BP	GO:0140029	exocytic process	25/4749	80/18670	0.1432	0.4063	0.3306	STX11/BLOC1S6/P2RX1/BTK/SNAP47/CAMK2A/VPS33B/RAB3D/SNAP29/SCFD2/STX1B/SCRIB/STX19/SNAP23/PPFIA3/VAMP3/EXOC6B/ERC2/SNAPIN/NAPB/VTI1B/STX2/RAB15/RALB/SV2A	25
BP	GO:0071103	DNA conformation change	92/4749	327/18670	0.1434	0.4067	0.3309	CENPA/HJURP/CDCA5/NCAPG/HMGB3/CDK1/ASF1B/TOP2A/CENPM/TOP3A/CHAF1A/NUSAP1/MCM4/TREX1/ERCC6L/MCM5/NCAPD2/CHAF1B/RAD54L/CENPW/DDB2/HMGB1/SIRT6/SPTY2D1/NASP/RAD51/NAP1L2/CCNB1/MCM2/CDC45/PIF1/GINS2/CENPT/UBB/GINS1/POLQ/CENPO/GINS4/XRCC6/ZRANB3/RFC2/RPS27A/MCM7/RAD23B/HELQ/DSCC1/UBA52/NAP1L3/ERCC8/GATAD1/CENPI/RECQL5/CDKN2A/BANF1/CHTF8/RNF8/CENPP/NCAPH/CENPN/UBN1/MCM3/ERCC2/GTF2H2/TSPYL1/PHF13/RECQL4/GTF2H1/HELLS/OIP5/DFFB/POT1/DDX11/DNA2/TSPYL4/CHMP1A/KAT6B/NCAPH2/MNAT1/HELB/CETN2/CENPV/NAP1L5/GTF2H5/XPA/MCPH1/WRN/PHF23/CUL4A/ASF1A/KAT6A/CENPK/RAD54B	92
BP	GO:0009743	response to carbohydrate	66/4749	230/18670	0.1435	0.4069	0.331	EGR1/IL1B/TXNIP/CDT1/ITGA2/ICAM1/SRF/RAC1/LDHA/PIM3/CLEC7A/COL6A2/SMARCB1/TIAM1/ARRB1/ENY2/C2CD2L/SRI/IGF1R/MAP2K6/EIF2B3/GJD3/LGALS1/CASR/TCF7L2/SMARCA4/NAMPT/TRPM4/NADK/OXCT1/PFKFB2/LRP1/SLC26A6/ACVR1C/ACVR2B/PRKCE/SIDT2/LRP5L/ZNF236/CYBA/MAP2K4/BRSK2/NDUFA9/GHRL/ADIPOQ/ERN1/RAB11FIP5/COLEC12/ZFP36L1/GCLC/PRKCB/PFKL/PPARD/SLC9B2/CYP7A1/ATG7/TGFB1/ADNP/NDUFAF2/SESN2/PDX1/GIPR/SYBU/ERCC1/BAD/NME2	66
BP	GO:0008584	male gonad development	41/4749	138/18670	0.1451	0.4112	0.3345	ASPM/ICAM1/NTRK1/KIF18A/BAX/NASP/PLEKHA1/NUDT1/NKX2-1/RRM1/RAB13/UBB/ARID5B/FGF9/BIK/SDC1/PATZ1/TBC1D20/FNDC3A/SOX8/NCOA4/REC8/CITED2/BCL2L1/ADAM15/CTNNA1/RBMY1B/SFRP1/ESR1/KDM5A/TNFSF10/HOXA11/INSR/NUPR1/ARID4A/WDR48/TMF1/RARA/CCND1/GATA3/ERCC1	41
BP	GO:0050688	regulation of defense response to virus	23/4749	73/18670	0.1453	0.4114	0.3347	IL1B/IFIT1/TSPAN32/PQBP1/IL2RA/MMP12/DTX3L/SEC14L1/NPLOC4/TRIM44/IL12RB1/RNF216/ZC3H12A/BIRC3/C1QBP/TSPAN6/STAT1/HTRA1/ANKRD17/ZCCHC3/USP17L2/TRIM15/IL23A	23
BP	GO:0071867	response to monoamine	13/4749	38/18670	0.1457	0.4122	0.3354	NR4A3/PDE4D/PDE4B/ADCY6/ATF4/DRD1/ATP2B4/GABPA/SIRT2/ADIPOQ/RNLS/ID1/MAPK1	13
BP	GO:0071869	response to catecholamine	13/4749	38/18670	0.1457	0.4122	0.3354	NR4A3/PDE4D/PDE4B/ADCY6/ATF4/DRD1/ATP2B4/GABPA/SIRT2/ADIPOQ/RNLS/ID1/MAPK1	13
BP	GO:0034330	cell junction organization	82/4749	290/18670	0.1468	0.4153	0.3378	PLEC/VEGFA/SDC4/FSCN1/ITGA2/CSF1R/SRF/RAC1/PERP/CBFB/CORO1C/CD9/NF2/TNF/CTTN/ACTG1/SMAD7/SRC/SNAI1/MAPRE2/TRIP6/RAB13/TGFB3/CD177/LIMS1/PLEKHA7/MPP7/GJD3/PRKCA/MPP5/CLASP2/WDPCP/VASP/PRKCI/LIMCH1/ITGA6/ACTN4/DUSP22/PKP4/FLOT1/S100A10/IQSEC1/LRP1/THY1/CADM1/XIRP2/CAPZA1/RAPGEF1/EPB41L5/CDH26/CD151/ECT2/WDR1/CDH9/PARD6G/ZNF703/CTNNA1/RAPGEF2/DLG5/SFRP1/SDK2/F2R/ARVCF/PARD6B/ARF6/APC/BCR/PARD6A/ARL2/FZD5/WHAMM/PIP5K1A/TGFB1/BCAS3/CDC42/CDH5/FMN1/LAMA5/LDB1/ILK/ACTB/GJA5	82
BP	GO:0014909	smooth muscle cell migration	28/4749	91/18670	0.1471	0.4156	0.3381	NR4A3/ITGA2/TRIB1/PDGFA/PLAU/SERPINE1/SORL1/PLAT/SRC/CORO1B/PLXNA1/PAK1/FGF9/IGFBP3/DOCK5/AIF1/VTN/ARPC5/LRP1/CRK/DDR1/ADIPOQ/TPM1/ADAMTS1/PPARD/HAS2/PDGFB/ILK	28
BP	GO:0051899	membrane depolarization	28/4749	91/18670	0.1471	0.4156	0.3381	ADORA2A/MLLT11/YWHAH/ABCD1/RANGRF/SMAD7/TSPO/SRC/IFI6/SCN1B/SCN9A/HCN2/KCNJ2/PPP2R3C/CCK/TRPM4/NTSR1/PARK7/JUN/CAMK2D/KCNH2/FZD9/GCLC/CACNB2/NPFF/P2RX7/SLMAP/GJA5	28
BP	GO:0046486	glycerolipid metabolic process	115/4749	414/18670	0.1472	0.4159	0.3383	TTC7A/MBOAT7/PTPN13/GK/CSF1R/PDGFA/CPNE7/SBF1/DGKD/PCTP/MFSD2A/MTMR3/SOCS2/SERINC3/AGPAT3/ABHD16A/PLBD1/TTC7B/LDLR/AGPAT2/GPX1/THEM5/PLEKHA1/GDPD3/SORL1/FITM2/SOCS3/DGKZ/INPP4A/FABP5/PLA2G12A/HTR2A/PIGK/LPCAT2/SH3YL1/TMEM86B/PIGH/ACSL1/TMEM150A/PIK3R5/PITPNM1/GDPD1/PIKFYVE/DPM2/MTMR9/IMPA2/PLEKHA2/LPCAT3/PIP5K1B/LMF1/ACP6/PIGQ/INSIG1/PI4K2A/PIGO/STARD10/SLA2/FPR2/PLEKHA8/AGAP2/LPCAT4/INPP1/PIGC/RAB38/PTPMT1/MTMR14/PLA2G15/ACSL4/PNPLA6/FAM126B/MOGAT1/PRDX6/PIGW/PIK3C3/IP6K1/CPT1A/PLA2G2A/GDE1/DGAT2/TAMM41/APOBR/LCLAT1/CETP/PIP4K2A/PIK3R4/PIGM/PTDSS1/PIGA/IP6K2/AGK/PIP4K2B/PLA2G5/ATM/TAZ/PIP5K1A/GPCPD1/PLCB1/ALDH5A1/GALR2/SLC22A4/GPAT2/HADHB/PLB1/MBOAT1/PLEKHA3/FABP12/PDGFB/IP6K3/PIGG/LPIN1/PIGT/CRLS1/PGS1/SIRT1/SLC44A1	115
BP	GO:0097755	positive regulation of blood vessel diameter	19/4749	59/18670	0.1481	0.4181	0.3402	ADORA2A/BBS2/GPX1/HMOX1/EPHX2/DOCK5/CASR/KCNMB1/ITGA1/MKKS/DRD1/BDKRB2/PTPRM/ADM/PLOD3/PPARD/PTAFR/SCPEP1/GJA5	19
BP	GO:0099518	vesicle cytoskeletal trafficking	17/4749	52/18670	0.1486	0.419	0.3409	KIF23/KIF1C/MYO5A/BLOC1S6/BLOC1S1/CNIH2/HTT/FYCO1/BLOC1S4/ACTN4/AP3D1/DTNBP1/AP3M2/SNAPIN/RAB1A/AP3B2/SYBU	17
BP	GO:1990089	response to nerve growth factor	17/4749	52/18670	0.1486	0.419	0.3409	NTRK2/NTRK1/HSPA5/E2F1/NTRK3/KAT2A/RPS3/MICALL1/CORO1A/RAPGEF1/UBE3A/CRK/RAPGEF2/CDC5L/ARF6/NTF3/ID1	17
BP	GO:0007250	activation of NF-kappaB-inducing kinase activity	7/4749	18/18670	0.1491	0.4193	0.3411	TIRAP/TNFRSF10B/TRAF4/IRAK1/TLR6/TRAF2/TRAF6	7
BP	GO:0044320	cellular response to leptin stimulus	7/4749	18/18670	0.1491	0.4193	0.3411	NR4A3/CCNA2/BBS2/STAT3/MKKS/ADIPOR1/SIRT1	7
BP	GO:0048739	cardiac muscle fiber development	7/4749	18/18670	0.1491	0.4193	0.3411	VEGFA/MYBPC3/MYOM1/MYO18B/MYH6/TCAP/MYBPC2	7
BP	GO:0051023	regulation of immunoglobulin secretion	7/4749	18/18670	0.1491	0.4193	0.3411	TNFSF4/GPI/TNF/TNFRSF4/HLA-E/TRAF2/TRAF6	7
BP	GO:0070230	positive regulation of lymphocyte apoptotic process	7/4749	18/18670	0.1491	0.4193	0.3411	IL10/PDCD1/PRELID1/LGALS9/BAX/IDO1/P2RX7	7
BP	GO:0090026	positive regulation of monocyte chemotaxis	7/4749	18/18670	0.1491	0.4193	0.3411	CCR1/HMGB1/CXCL10/SERPINE1/CCR2/AIF1/FPR2	7
BP	GO:1900221	regulation of amyloid-beta clearance	7/4749	18/18670	0.1491	0.4193	0.3411	SRF/TNF/CLU/LRPAP1/LRP1/IFNGR1/IL4	7
BP	GO:0010675	regulation of cellular carbohydrate metabolic process	42/4749	142/18670	0.1492	0.4194	0.3412	PHLDA2/IGFBP4/PGAM1/CBFA2T3/SIRT6/PPP1CB/PMAIP1/MTOR/STAT3/SRC/CRY1/KAT2A/IGFBP3/FOXO1/RORC/DDIT4/PFKFB2/SLC45A3/ADIPOR1/MAEA/PPP1R3E/NTSR1/C1QTNF3/EPM2AIP1/PRKCE/GSK3A/PHKG2/GNMT/ADIPOQ/DGAT2/ACACB/P2RY1/INSR/NUPR1/SLC35B4/CLK2/COX11/SESN2/PTAFR/BAD/PPP1R3B/SIRT1	42
BP	GO:0010522	regulation of calcium ion transport into cytosol	31/4749	102/18670	0.1497	0.4205	0.3421	PTPN6/PML/JSRP1/BAX/CXCL10/TRPC1/MYO5A/PDE4D/SRI/PKD2/HTT/GSTO1/CORO1A/CXCL9/BAK1/DRD1/FKBP1A/THY1/CD19/NTSR1/PRKCE/CYBA/LACRT/IL13/CAMK2D/P2RX5/PRNP/F2R/TGFB1/P2RX7/FYN	31
BP	GO:0098869	cellular oxidant detoxification	31/4749	102/18670	0.1497	0.4205	0.3421	TXNDC17/ALOX5AP/TNF/GPX1/PRDX3/PRDX5/HBA2/NQO1/DHFR/GSTO1/NXN/FANCC/IPCEF1/TP53INP1/GPX4/PARK7/TXNRD3/MPO/HBG1/PRDX6/GSTT1/HBB/MGST2/NNT/MGST3/GSTK1/CCS/TXNRD2/GSTZ1/SESN2/PRDX1	31
BP	GO:0051453	regulation of intracellular pH	26/4749	84/18670	0.1498	0.4206	0.3422	GRN/ATP6V0D1/SLC4A2/ATP6V0B/SLC4A3/ATP6V1E1/PPT1/ATP6V0C/SLC9A7/SLC4A11/ATP6V1A/ROGDI/SLC26A6/SLC4A10/TMEM175/CHP1/CA2/RAB38/SNAPIN/ATP6V1G1/SLC9B1/DMXL1/ATP6V1E2/DMXL2/CCDC115/SLC9A6	26
BP	GO:0035456	response to interferon-beta	10/4749	28/18670	0.1509	0.4229	0.3441	TREX1/IFITM2/BST2/UBE2G2/IFITM3/IFITM1/MNDA/IFI16/STAT1/NDUFA13	10
BP	GO:0042730	fibrinolysis	10/4749	28/18670	0.1509	0.4229	0.3441	PLAUR/ANXA2P2/PROS1/TMPRSS6/PLAU/SERPINE1/ANXA2/PLAT/KLKB1/SERPING1	10
BP	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway	10/4749	28/18670	0.1509	0.4229	0.3441	PTPN6/LGALS3/CEACAM1/BTN2A2/LILRB4/EZR/DUSP22/PLCL2/THY1/PRNP	10
BP	GO:1902745	positive regulation of lamellipodium organization	10/4749	28/18670	0.1509	0.4229	0.3441	FSCN1/RAC1/CORO1C/MTOR/SRC/CORO1B/TWF2/RAC2/WASF2/CDC42	10
BP	GO:0032869	cellular response to insulin stimulus	62/4749	216/18670	0.1515	0.4244	0.3453	IL1B/RAB31/PPARG/SH2B2/CYFIP1/ATP6V0D1/MZB1/CEACAM1/SOCS2/EIF4EBP1/SYAP1/SLC2A8/PTPN1/ATP6V0B/ESRRA/SORL1/MYO5A/SRC/SOCS3/PKM/CFLAR/RAB13/ATP6V1E1/IGF1R/PAK1/ENHO/FFAR3/SLC2A4/ATP6V0C/FOXO1/PHIP/PRKCI/ATP6V1A/SP1/ADIPOR1/SLA2/GNAI2/INSRR/APRT/GSK3A/RARRES2/ATP6V1G1/BGLAP/ADIPOQ/GPR21/FER/ZFP36L1/GCLC/CPEB1/PRKCB/INSR/APC/HDAC9/STAT1/ATP6V1E2/NUCKS1/SHC1/GKAP1/LPIN1/TRIB3/USO1/SIRT1	62
BP	GO:0048638	regulation of developmental growth	97/4749	347/18670	0.1528	0.4279	0.3481	MAPK11/VEGFA/NOTCH1/PLAC8/TP73/CDK1/CDKN1A/DUSP10/SRF/PHLDA2/BCL11A/DUSP6/CYFIP1/CDK5/BBS2/SPP1/PTCH1/SOCS2/SEMA4C/TNFRSF12A/GAMT/CSF1/SEMA7A/CTTN/MTOR/ZFYVE27/STAT3/SEMA3G/PIM1/FXN/CCNB1/PARP2/NKD1/SYT4/SEMA6C/PLS1/NTRK3/PAK1/CPNE5/FGF9/RBPJ/SEMA6B/MBD5/HLX/SMURF1/CARM1/FGF13/EZR/STK3/ARHGAP4/TWF2/L1CAM/NRK/TNKS2/MKKS/LRP1/LIMK1/WWC2/CACNA2D2/TTL/BASP1/SH3PXD2B/SEMA3B/IST1/YAP1/IL7/SEMA5B/GSK3A/RASAL1/SFRP1/GHRL/GPR21/POR/PTPRS/SERP1/STAT5A/ACACB/SEMA4D/INSR/BMP10/FGF8/ATRN/DLL1/PPARD/RAG2/MYH6/PLCB1/RUFY3/SEMA5A/RTN4R/ADNP/MAPK1/TRPC5/MIR17HG/KCNK2/GDI1/ILK	97
BP	GO:1903076	regulation of protein localization to plasma membrane	29/4749	95/18670	0.153	0.4282	0.3483	SQSTM1/ITGA3/CDK5/LGALS3/TNF/AKAP5/RANGRF/GRIPAP1/RHOG/CLIP3/PLS1/PTPN9/SPTBN1/EZR/LRRC15/PRKCI/STAC3/LRP1/STAC/PRKCE/BCL2L1/VTI1B/PRNP/LDLRAP1/GOPC/ARF6/TGFB1/CNST/ACTB	29
BP	GO:0043484	regulation of RNA splicing	40/4749	135/18670	0.1531	0.4282	0.3484	RBM22/PQBP1/HSPA1A/NUP98/SMU1/PTBP1/RNPS1/SRSF4/RPS13/CIRBP/FAM172A/FASTK/CELF6/RBM4B/AKAP17A/SF3B4/FMR1/DDX17/MBNL3/RBM17/ZNF326/PRPF19/C9orf78/MAGOH/RBMY1B/PRDX6/METTL16/RBM38/CLK3/ERN1/RBM11/C1QBP/AHNAK/HNRNPL/RBM3/CWC22/CLK2/POLR2A/ESRP2/YTHDC1	40
BP	GO:0050766	positive regulation of phagocytosis	22/4749	70/18670	0.1548	0.4329	0.3522	IL1B/RAB31/PPARG/ITGA2/SIRPA/CLEC7A/TNF/IL2RB/MERTK/IL2RG/CCL2/IL15RA/PTPRC/CD300LF/CD47/LRP1/RAB27A/RAPGEF1/FPR2/CYBA/LMAN2/BCR	22
BP	GO:1901989	positive regulation of cell cycle phase transition	32/4749	106/18670	0.1551	0.4335	0.3527	ESPL1/CDCA5/UBE2C/FAM83D/CDK1/CDT1/DTL/HSPA2/DLGAP5/DYRK3/CDC25A/CDC6/CDC25C/WNT10B/CCNB1/FBXO5/DBF4B/CDC45/AIF1/BRD4/EZH2/CDK10/ANAPC11/PBX1/MTA3/ADAMTS1/ANKRD17/PLCB1/TGFB1/CUL4A/CDC25B/CCND1	32
BP	GO:0071375	cellular response to peptide hormone stimulus	90/4749	321/18670	0.1552	0.4335	0.3527	NR4A1/IL1B/RAB31/NR4A3/PPARG/SH2B2/CCNA2/CYFIP1/ATP6V0D1/MZB1/CEACAM1/CDC6/SOCS2/EIF4EBP1/SYAP1/SLC2A8/PTPN1/ATP6V0B/ESRRA/STAT3/ADCY4/SORL1/MYO5A/SRC/SOCS3/PKM/CFLAR/CAMK2A/RAB13/ATP6V1E1/IGF1R/PAK1/ENHO/ADCY6/FFAR3/SLC2A4/MBD5/ATP6V0C/FOXO1/PHIP/ANXA5/PRKCI/ATP6V1A/SP1/ADIPOR1/SLA2/ARG1/GNAI2/INSRR/TSHR/CA2/CRK/ADCY3/CYBA/APRT/GSK3A/RARRES2/ATP6V1G1/BGLAP/GHRL/CDC5L/ADIPOQ/GPR21/POR/FER/STAT5A/ZFP36L1/GCLC/CPEB1/PRKCB/PRKACB/INSR/MAX/ADCY9/APC/HDAC9/STAT1/ATP6V1E2/CYP11A1/NUCKS1/TGFB1/JAK3/SHC1/GKAP1/LPIN1/FYN/TRIB3/MGARP/USO1/SIRT1	90
BP	GO:0033144	negative regulation of intracellular steroid hormone receptor signaling pathway	12/4749	35/18670	0.1562	0.4361	0.3548	KANK2/CYP7B1/TP63/CRY1/SMARCA4/PIAS2/ARNTL/SFRP1/LBH/STRN3/NCOR1/SIRT1	12
BP	GO:0060251	regulation of glial cell proliferation	12/4749	35/18670	0.1562	0.4361	0.3548	IL1B/NOTCH1/TNF/E2F1/SKI/MTOR/TSPO/ETV5/PRKCI/LTA/SOX11/DICER1	12
BP	GO:0046622	positive regulation of organ growth	20/4749	63/18670	0.1568	0.4366	0.3552	NOTCH1/CDK1/MTOR/PIM1/CCNB1/PARP2/FGF9/RBPJ/HLX/CACNA2D2/BASP1/YAP1/IL7/SERP1/ACACB/BMP10/FGF8/RAG2/MAPK1/MIR17HG	20
BP	GO:0090181	regulation of cholesterol metabolic process	20/4749	63/18670	0.1568	0.4366	0.3552	ABCG1/LDLR/PMVK/FDPS/SCD/EPHX2/LMF1/SP1/SQLE/ARV1/POR/DGAT2/LDLRAP1/ACACB/FASN/MBTPS2/TTC39B/CYP7A1/SREBF2/NFYB	20
BP	GO:0051282	regulation of sequestering of calcium ion	38/4749	128/18670	0.1571	0.4366	0.3552	PTPN6/CHERP/JSRP1/NOL3/BAX/CXCL10/TRPC1/SLC25A23/MYO5A/PDE4D/HTR2A/CCL3/SRI/PKD2/CCR5/HTT/GSTO1/TPCN1/PTPRC/CORO1A/RASA3/ANXA5/CXCL9/DRD1/FKBP1A/DDIT3/THY1/CD19/NTSR1/PRKCE/CYBA/LACRT/IL13/CAMK2D/F2R/PLCB1/TGFB1/P2RX7	38
BP	GO:0042113	B cell activation	87/4749	310/18670	0.1573	0.4366	0.3552	HMGB3/IL21/CDKN1A/IL10/BATF/NTRK1/EXO1/TXLNA/PTPN6/BCL3/BCL6/TIRAP/TNFSF4/TFRC/MZB1/MSH6/TNFRSF4/TLR4/BAX/TNFRSF21/FOXP3/ITM2A/CMTM7/CTLA4/ITFG2/SWAP70/CCR6/TP53BP1/SAMSN1/BTK/BST2/CD74/RBPJ/LYL1/FLT3/LGALS1/PPP2R3C/CD180/ZFP36L2/CD79B/PTPRC/CYLD/NFAM1/KLF6/SUPT6H/BAK1/NOD2/AICDA/IL27RA/SLA2/PLCL2/RNF8/CD19/AKAP17A/TNFRSF13B/MNDA/CR2/IL7R/APLF/IL7/POLM/IL13/SFRP1/CARD11/TNFSF13/IL4/NHEJ1/TYROBP/FZD9/ZFP36L1/MAD2L2/PRKCB/HDAC9/ATP11C/DLL1/ATM/POU2F2/RAG2/SLC39A10/TGFB1/JAK3/CXCR5/MIR17HG/ZAP70/ERCC1/BAD/RNF168	87
BP	GO:0046546	development of primary male sexual characteristics	41/4749	139/18670	0.1573	0.4366	0.3552	ASPM/ICAM1/NTRK1/KIF18A/BAX/NASP/PLEKHA1/NUDT1/NKX2-1/RRM1/RAB13/UBB/ARID5B/FGF9/BIK/SDC1/PATZ1/TBC1D20/FNDC3A/SOX8/NCOA4/REC8/CITED2/BCL2L1/ADAM15/CTNNA1/RBMY1B/SFRP1/ESR1/KDM5A/TNFSF10/HOXA11/INSR/NUPR1/ARID4A/WDR48/TMF1/RARA/CCND1/GATA3/ERCC1	41
BP	GO:0006000	fructose metabolic process	6/4749	15/18670	0.1581	0.4366	0.3552	PFKFB3/ALDOC/PFKFB4/PFKFB2/ALDOA/ALDOB	6
BP	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	6/4749	15/18670	0.1581	0.4366	0.3552	TSEN2/FAM98B/TSEN15/TSEN34/TRPT1/CPSF1	6
BP	GO:0006491	N-glycan processing	6/4749	15/18670	0.1581	0.4366	0.3552	MGAT4B/MGAT4A/PRKCSH/GANAB/MAN1A1/ST8SIA3	6
BP	GO:0009109	coenzyme catabolic process	6/4749	15/18670	0.1581	0.4366	0.3552	ABCD1/VCP/PDXP/MTHFS/NUDT17/ASPDH	6
BP	GO:0009209	pyrimidine ribonucleoside triphosphate biosynthetic process	6/4749	15/18670	0.1581	0.4366	0.3552	NME4/NME3/CTPS2/UCK2/NME9/NME2	6
BP	GO:0032239	regulation of nucleobase-containing compound transport	6/4749	15/18670	0.1581	0.4366	0.3552	IWS1/NUP153/SUPT6H/CPSF6/RBM27/NCBP2	6
BP	GO:0032486	Rap protein signal transduction	6/4749	15/18670	0.1581	0.4366	0.3552	KIF14/TIMP2/SGSM3/PLK2/RAPGEF1/RAPGEF2	6
BP	GO:0042921	glucocorticoid receptor signaling pathway	6/4749	15/18670	0.1581	0.4366	0.3552	YWHAH/NR3C1/CRY1/ARID1A/PPP5C/ARNTL	6
BP	GO:0043101	purine-containing compound salvage	6/4749	15/18670	0.1581	0.4366	0.3552	HPRT1/PNP/AMPD2/MTAP/APRT/AMPD3	6
BP	GO:0043508	negative regulation of JUN kinase activity	6/4749	15/18670	0.1581	0.4366	0.3552	DUSP10/DNAJA1/PDCD4/SFRP1/AIDA/ZNF675	6
BP	GO:0045073	regulation of chemokine biosynthetic process	6/4749	15/18670	0.1581	0.4366	0.3552	EGR1/IL1B/TNF/HMOX1/CD74/SIGIRR	6
BP	GO:0045475	locomotor rhythm	6/4749	15/18670	0.1581	0.4366	0.3552	EGR1/MTOR/ZFHX3/MTA1/NCOR1/MC3R	6
BP	GO:0045838	positive regulation of membrane potential	6/4749	15/18670	0.1581	0.4366	0.3552	PIAS3/CTNS/VCP/BID/NNT/BAD	6
BP	GO:0046321	positive regulation of fatty acid oxidation	6/4749	15/18670	0.1581	0.4366	0.3552	TWIST1/NR4A3/PPARG/ABCD1/ABCD2/CPT1A	6
BP	GO:0060026	convergent extension	6/4749	15/18670	0.1581	0.4366	0.3552	NKD1/PTK7/DVL1/MKKS/SFRP1/LRP6	6
BP	GO:0060339	negative regulation of type I interferon-mediated signaling pathway	6/4749	15/18670	0.1581	0.4366	0.3552	TREX1/MMP12/SCRIB/SAMHD1/CNOT7/YTHDF3	6
BP	GO:1900037	regulation of cellular response to hypoxia	6/4749	15/18670	0.1581	0.4366	0.3552	ENO1/NOL3/USP19/PINK1/CD34/KCNK2	6
BP	GO:1901841	regulation of high voltage-gated calcium channel activity	6/4749	15/18670	0.1581	0.4366	0.3552	GEM/REM1/PDE4B/SRI/REM2/CACNB2	6
BP	GO:2000484	positive regulation of interleukin-8 secretion	6/4749	15/18670	0.1581	0.4366	0.3552	LGALS9/FFAR2/FCN1/TLR2/CD58/F2R	6
BP	GO:0046148	pigment biosynthetic process	18/4749	56/18670	0.1583	0.4372	0.3557	MTHFD1L/CPOX/TRPC1/CTNS/TSPO/FXN/MYO5A/IBA57/HPRT1/MTHFD1/ASIP/OCA2/APRT/RAPGEF2/PPOX/PRPS1/DDT/TYRP1	18
BP	GO:0002639	positive regulation of immunoglobulin production	14/4749	42/18670	0.1586	0.4374	0.3559	TNFSF4/TFRC/MZB1/GPI/TNFRSF4/IL4R/TP53BP1/PTPRC/HLA-E/IL13/TNFSF13/IL4/MAD2L2/TGFB1	14
BP	GO:0017145	stem cell division	14/4749	42/18670	0.1586	0.4374	0.3559	NOTCH1/ASPM/TEAD3/NAP1L2/ETV5/ARHGEF2/WWTR1/CDK2AP2/ZFP36L2/FGF13/PRDM15/GNL3/WNT7A/LBH	14
BP	GO:0030838	positive regulation of actin filament polymerization	30/4749	99/18670	0.1587	0.4375	0.356	CDC42EP4/ICAM1/HCK/CYFIP1/SNX9/GSN/CTTN/MTOR/BAG4/CDC42EP1/TENM1/CORO1B/WHAMMP3/PFN2/HIP1R/ARPC1B/PICK1/CORO1A/VASP/ARPC5/PRKCE/ACTR3B/FER/ARF6/WHAMM/AP1AR/C15orf62/WAS/FMN1/RAC3	30
BP	GO:1901570	fatty acid derivative biosynthetic process	30/4749	99/18670	0.1587	0.4375	0.356	IL1B/PTGIS/ALOX5AP/SLC25A1/TECR/SCD/GGT1/FAR2/FABP5/CD74/PPT1/HMGCL/ACSL1/HSD17B8/ALOX5/GGTLC2/TBXAS1/ELOVL7/PIBF1/PTGES2/ELOVL1/BDH2/ACSL4/MGST2/GGT7/FASN/MGST3/HPGD/PLA2G5/SIRT1	30
BP	GO:0035094	response to nicotine	16/4749	49/18670	0.159	0.438	0.3563	NTRK1/TNF/CHRNA5/MSX1/HMOX1/ABAT/KCNK1/CNR1/CHRNA1/IL13/CHRNA3/CHRNG/MAPK1/GNAT3/PDX1/BAD	16
BP	GO:1903018	regulation of glycoprotein metabolic process	16/4749	49/18670	0.159	0.438	0.3563	HBEGF/ITM2A/POMT2/CST3/NECAB3/FKTN/TCF7L2/ACOT8/CHP1/ACER2/ITM2B/ITM2C/RAB1A/PLCB1/JAK3/RAB1B	16
BP	GO:0007045	cell-substrate adherens junction assembly	25/4749	81/18670	0.1594	0.4383	0.3566	VEGFA/SDC4/ITGA2/RAC1/CORO1C/CTTN/SRC/TRIP6/LIMS1/CLASP2/WDPCP/LIMCH1/DUSP22/S100A10/LRP1/THY1/EPB41L5/SFRP1/BCR/WHAMM/PIP5K1A/BCAS3/FMN1/LAMA5/LDB1	25
BP	GO:0048041	focal adhesion assembly	25/4749	81/18670	0.1594	0.4383	0.3566	VEGFA/SDC4/ITGA2/RAC1/CORO1C/CTTN/SRC/TRIP6/LIMS1/CLASP2/WDPCP/LIMCH1/DUSP22/S100A10/LRP1/THY1/EPB41L5/SFRP1/BCR/WHAMM/PIP5K1A/BCAS3/FMN1/LAMA5/LDB1	25
BP	GO:0048708	astrocyte differentiation	25/4749	81/18670	0.1594	0.4383	0.3566	LIF/IL1B/NOTCH1/ADORA2A/TTBK1/GRN/CNTF/TNF/TLR4/LDLR/STAT3/NTRK3/DRD1/LRP1/SOX8/FPR2/VIM/PRPF19/IFNGR1/S100A8/C1QA/MBD1/DLL1/MAPK1/GCM1	25
BP	GO:1902806	regulation of cell cycle G1/S phase transition	58/4749	202/18670	0.16	0.44	0.358	KIF14/GTSE1/E2F7/E2F8/FAM83D/CDK1/CDKN1A/AURKA/KANK2/CDKN2B/KLF4/PTPN6/ZNF385A/GPNMB/CDC6/PML/E2F1/PLK2/BAX/BTN2A2/CDC25C/CDKN2C/GADD45A/CCNB1/SFN/RPL26/CDC45/CDK2/RFWD3/CDK2AP2/PKD2/CCL2/FBXO31/BID/CARM1/AIF1/CNOT3/EZH2/CDK10/TFDP2/MUC1/CDKN2A/ATP2B4/MDM4/RBL2/PSME2/CNOT7/TMEM14B/GIGYF2/GML/CHEK2/ADAMTS1/ATM/ANKRD17/PLCB1/CUL4A/ZNF655/CCND1	58
BP	GO:0006024	glycosaminoglycan biosynthetic process	33/4749	110/18670	0.1603	0.4406	0.3584	IL1B/SDC4/HS3ST3B1/HS3ST3A1/CHST15/GPC1/CHPF2/B3GAT3/OGN/CSGALNACT1/SDC2/SLC35D2/SLC35D1/SDC1/B3GALT6/B3GNT2/CHST7/EXT1/EXTL2/GPC2/DSEL/ST3GAL3/HS6ST1/HAS3/CHPF/B4GALT5/CHST13/XYLT1/TGFB1/HAS2/PDGFB/B4GALT4/B4GALT7	33
BP	GO:0006606	protein import into nucleus	42/4749	143/18670	0.1614	0.4427	0.3602	TXNIP/CDKN1A/RBM22/PML/KPNA2/NUP98/RGPD2/MMP12/LMNA/STAT3/CSE1L/FGF9/NUP153/TMCO6/RPL23/DRD1/NUP88/NOLC1/RANBP6/FAM53B/CHP1/EFCAB7/KPNA3/NFKBIA/CABP1/POM121C/ECT2/ARNTL/NUP50/ZC3H12A/BAG3/FAM53A/RAB23/POM121L2/SNUPN/NUP93/NUP35/TGFB1/RGPD1/MAPK1/NUP62/TNPO1	42
BP	GO:0002335	mature B cell differentiation	9/4749	25/18670	0.1618	0.4427	0.3602	BCL3/ITM2A/CMTM7/ITFG2/LGALS1/PLCL2/CD19/DLL1/POU2F2	9
BP	GO:0019054	modulation by virus of host process	9/4749	25/18670	0.1618	0.4427	0.3602	KPNA2/NTRK3/SCRIB/KPNA3/CCNK/BCL2L1/ZC3H12A/ATG7/BAD	9
BP	GO:0021680	cerebellar Purkinje cell layer development	9/4749	25/18670	0.1618	0.4427	0.3602	KIF14/FAIM2/MYH10/HSPA5/CEND1/SEZ6L/AGTPBP1/DLL1/LDB1	9
BP	GO:0032461	positive regulation of protein oligomerization	9/4749	25/18670	0.1618	0.4427	0.3602	SNX9/BAX/PMAIP1/BMF/CLU/BIK/CCK/BID/TRABD2B	9
BP	GO:0050927	positive regulation of positive chemotaxis	9/4749	25/18670	0.1618	0.4427	0.3602	VEGFA/ITGA2/CCR4/NTRK3/S1PR1/CASR/F3/NTF3/VEGFC	9
BP	GO:0051654	establishment of mitochondrion localization	9/4749	25/18670	0.1618	0.4427	0.3602	UXT/UBB/MAP1S/LRPPRC/RHOT2/NEFL/UCHL1/SYBU/MGARP	9
BP	GO:0051894	positive regulation of focal adhesion assembly	9/4749	25/18670	0.1618	0.4427	0.3602	VEGFA/SDC4/RAC1/LIMS1/S100A10/THY1/EPB41L5/SFRP1/FMN1	9
BP	GO:0060561	apoptotic process involved in morphogenesis	9/4749	25/18670	0.1618	0.4427	0.3602	VDR/NOTCH1/JAG2/SPI1/BAX/SCRIB/BAK1/TNFRSF1B/FZD5	9
BP	GO:0072677	eosinophil migration	9/4749	25/18670	0.1618	0.4427	0.3602	CCL22/DAPK2/LGALS3/CCL3/PTGER4/CCL2/CCL23/CCL7/CCL15	9
BP	GO:0097186	amelogenesis	9/4749	25/18670	0.1618	0.4427	0.3602	PERP/CSF3R/FAM20C/FOXO1/CNNM4/ITGA6/AMTN/KLK5/AMELX	9
BP	GO:0048199	vesicle targeting, to, from or within Golgi	23/4749	74/18670	0.1624	0.4439	0.3611	SEC13/GORASP1/SEC24D/MCFD2/F5/STX5/SEC16A/CNIH2/ANKRD28/TBC1D20/CEP19/TMED9/GBF1/TMED10/CTSZ/TRAPPC4/RAB1A/AP1AR/PPP6C/PEF1/PPP6R1/RAB1B/USO1	23
BP	GO:0048259	regulation of receptor-mediated endocytosis	31/4749	103/18670	0.1643	0.4463	0.3631	VEGFA/RAC1/ANXA2P2/HIP1/SERPINE1/ANXA2/ARRB1/SDCBP/CLU/SFRP4/PPT1/UNC119/HIP1R/PICK1/LRPAP1/FLOT1/VTN/SCRIB/AAK1/FMR1/DNAJC6/SYT11/ATAD1/RABGEF1/UBQLN2/CD2AP/IL4/LDLRAP1/ARF6/NTF3/DLG4	31
BP	GO:1903391	regulation of adherens junction organization	21/4749	67/18670	0.1651	0.4463	0.3631	VEGFA/SDC4/RAC1/CORO1C/SRC/MAPRE2/LIMS1/CLASP2/WDPCP/LIMCH1/DUSP22/S100A10/IQSEC1/LRP1/THY1/EPB41L5/SFRP1/ARF6/BCAS3/FMN1/LDB1	21
BP	GO:0030282	bone mineralization	34/4749	114/18670	0.1654	0.4463	0.3631	TWIST1/ISG15/CCR1/GPNMB/BMP2K/SBNO2/WNT10B/NBR1/CCL3/TGFB3/PTHLH/PHEX/FAM20C/ZBTB40/BCOR/S1PR1/ATRAID/TRPM4/SBDS/CYP27B1/ERCC2/ACVR2B/SRGN/KLF10/BGLAP/EIF2AK3/FZD9/TXLNG/FBXL15/AXIN2/TMEM119/CER1/TGFB1/P2RX7	34
BP	GO:0045446	endothelial cell differentiation	34/4749	114/18670	0.1654	0.4463	0.3631	IL1B/VEGFA/NOTCH1/ICAM1/ANXA2P2/CEACAM1/TNF/PROC/COL18A1/TJP2/ANXA2/MYADM/GPX1/PDE4D/RBPJ/S1PR1/JAG1/EZR/ATOH8/WNT7A/PPP1R16B/RAPGEF1/ACVR2B/SCUBE1/RAPGEF2/PTPRS/EDF1/FASN/PLOD3/DLL1/ID1/CDH5/LAMA5/ARHGEF26	34
BP	GO:0043524	negative regulation of neuron apoptotic process	43/4749	147/18670	0.1654	0.4463	0.3631	KIF14/TYRO3/NR4A3/ADORA2A/NTRK2/FAIM2/NTRK1/GRN/CNTF/VSTM2L/STAMBP/FOXB1/BAX/HMOX1/ARRB1/AXL/TGFB3/PPT1/AMBRA1/CCL2/PINK1/CORO1A/PRKCI/LRP1/PARK7/JUN/TFAP2B/AGAP2/CEBPB/BCL2L1/MAP2K4/F2R/FZD9/GCLC/FGF8/NEFL/NTF3/POU4F1/NMNAT1/ADNP/CX3CR1/FYN/ILK	43
BP	GO:0045017	glycerolipid biosynthetic process	71/4749	251/18670	0.1656	0.4463	0.3631	PTPN13/GK/PDGFA/CPNE7/SBF1/PCTP/MFSD2A/MTMR3/AGPAT3/LDLR/AGPAT2/PLEKHA1/FITM2/DGKZ/INPP4A/FABP5/PLA2G12A/HTR2A/PIGK/LPCAT2/SH3YL1/PIGH/ACSL1/PIK3R5/PITPNM1/PIKFYVE/DPM2/MTMR9/PLEKHA2/PIP5K1B/ACP6/PIGQ/PI4K2A/PIGO/STARD10/FPR2/PLEKHA8/AGAP2/LPCAT4/PIGC/RAB38/PTPMT1/MTMR14/ACSL4/MOGAT1/PIGW/PIK3C3/PLA2G2A/DGAT2/TAMM41/LCLAT1/PIP4K2A/PIK3R4/PIGM/PTDSS1/PIGA/AGK/PIP4K2B/PLA2G5/ATM/TAZ/PIP5K1A/GPAT2/PLEKHA3/PDGFB/PIGG/LPIN1/PIGT/CRLS1/PGS1/SLC44A1	71
BP	GO:0010976	positive regulation of neuron projection development	79/4749	281/18670	0.166	0.4463	0.3631	SKIL/VEGFA/MAP6/ITGA3/NTRK2/FES/NTRK1/SRF/PLXNB2/GRN/CYFIP1/CNTF/CAMK1/PLXNB1/TNFRSF12A/HSPA5/CREB3L2/LRP8/SEMA7A/MTOR/CUX1/ZFYVE27/SCN1B/TIAM1/SYT4/CFLAR/AMIGO1/NTRK3/DVL3/PLXNA1/PAK1/PTK7/CPNE5/CRTC1/ARHGAP35/CBFA2T2/PTK6/PAK3/FBXO31/SMURF1/TMEM106B/PRKCI/TWF2/L1CAM/PLXND1/ITGA6/EZH2/SCARF1/DVL1/LRP1/TMEM30A/LIMK1/STYXL1/CNR1/GPC2/RAPGEF1/STK25/FMR1/IST1/RASAL1/RAPGEF2/NEGR1/DLG5/PARP6/LTK/PACSIN1/SEMA4D/ARHGDIA/LLPH/NEFL/RUFY3/SEMA5A/ADNP/TRPC5/GDI1/FYN/NME2/DLG4/ILK	79
BP	GO:1901532	regulation of hematopoietic progenitor cell differentiation	26/4749	85/18670	0.166	0.4463	0.3631	NOTCH1/TP73/CBFB/HSPA9/PSMD8/PSMD1/PSMD2/PSMF1/PSMD9/PSMA5/OSM/PSMB7/PSMD5/YAP1/PSME2/PSMB5/PSMB4/PSMA3/PSMD10/PSMB1/PSMD7/PSMB3/PSMC5/LDB1/GATA3/PSMD11	26
BP	GO:0002551	mast cell chemotaxis	5/4749	12/18670	0.1667	0.4463	0.3631	VEGFA/RAC1/SWAP70/RAC2/VEGFC	5
BP	GO:0002903	negative regulation of B cell apoptotic process	5/4749	12/18670	0.1667	0.4463	0.3631	AURKB/BCL6/CD74/SLC39A10/MIR17HG	5
BP	GO:0006465	signal peptide processing	5/4749	12/18670	0.1667	0.4463	0.3631	FURIN/SPPL3/SEC11C/PCSK5/SPCS3	5
BP	GO:0015697	quaternary ammonium group transport	5/4749	12/18670	0.1667	0.4463	0.3631	SLC25A45/SLC22A3/SLC38A2/SLC25A48/SLC22A4	5
BP	GO:0015867	ATP transport	5/4749	12/18670	0.1667	0.4463	0.3631	SLC25A23/SLC25A25/SLC25A5/SLC25A42/SLC25A4	5
BP	GO:0016045	detection of bacterium	5/4749	12/18670	0.1667	0.4463	0.3631	CD1D/PGLYRP3/TLR2/NOD2/TLR6	5
BP	GO:0016554	cytidine to uridine editing	5/4749	12/18670	0.1667	0.4463	0.3631	APOBEC3H/APOBEC3B/AICDA/RBM47/A1CF	5
BP	GO:0031392	regulation of prostaglandin biosynthetic process	5/4749	12/18670	0.1667	0.4463	0.3631	IL1B/FABP5/CD74/PIBF1/SIRT1	5
BP	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter	5/4749	12/18670	0.1667	0.4463	0.3631	EZH2/RECQL5/RNF8/EAPP/RNF168	5
BP	GO:0035751	regulation of lysosomal lumen pH	5/4749	12/18670	0.1667	0.4463	0.3631	GRN/PPT1/TMEM175/SNAPIN/CCDC115	5
BP	GO:0036005	response to macrophage colony-stimulating factor	5/4749	12/18670	0.1667	0.4463	0.3631	CSF1R/CSF1/TLR4/TLR2/FER	5
BP	GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	5/4749	12/18670	0.1667	0.4463	0.3631	CSF1R/CSF1/TLR4/TLR2/FER	5
BP	GO:0038180	nerve growth factor signaling pathway	5/4749	12/18670	0.1667	0.4463	0.3631	NTRK1/CORO1A/RAPGEF1/RAPGEF2/NTF3	5
BP	GO:0042368	vitamin D biosynthetic process	5/4749	12/18670	0.1667	0.4463	0.3631	VDR/IL1B/TNF/SNAI1/CYP27B1	5
BP	GO:0043383	negative T cell selection	5/4749	12/18670	0.1667	0.4463	0.3631	CD74/PTPRC/CD3E/THEMIS/ZAP70	5
BP	GO:0043476	pigment accumulation	5/4749	12/18670	0.1667	0.4463	0.3631	BLOC1S6/RAB32/AP3D1/RAB38/SHROOM3	5
BP	GO:0043482	cellular pigment accumulation	5/4749	12/18670	0.1667	0.4463	0.3631	BLOC1S6/RAB32/AP3D1/RAB38/SHROOM3	5
BP	GO:0045080	positive regulation of chemokine biosynthetic process	5/4749	12/18670	0.1667	0.4463	0.3631	EGR1/IL1B/TNF/HMOX1/CD74	5
BP	GO:0045416	positive regulation of interleukin-8 biosynthetic process	5/4749	12/18670	0.1667	0.4463	0.3631	TLR8/CLEC7A/TNF/TLR4/CD74	5
BP	GO:0045579	positive regulation of B cell differentiation	5/4749	12/18670	0.1667	0.4463	0.3631	BTK/PPP2R3C/IL7/ATP11C/BAD	5
BP	GO:0045955	negative regulation of calcium ion-dependent exocytosis	5/4749	12/18670	0.1667	0.4463	0.3631	NOTCH1/SYT4/GNAI2/FMR1/TRIM9	5
BP	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound	5/4749	12/18670	0.1667	0.4463	0.3631	CHRNA10/COL11A1/MKKS/STRC/TMC2	5
BP	GO:0051657	maintenance of organelle location	5/4749	12/18670	0.1667	0.4463	0.3631	GPSM2/ASPM/ATP2A1/UVRAG/POLR2M	5
BP	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation	5/4749	12/18670	0.1667	0.4463	0.3631	PMEPA1/SNX25/SMAD7/SMAD6/LDLRAD4	5
BP	GO:0060742	epithelial cell differentiation involved in prostate gland development	5/4749	12/18670	0.1667	0.4463	0.3631	NOTCH1/TP63/WDR77/FEM1B/RXRA	5
BP	GO:0070572	positive regulation of neuron projection regeneration	5/4749	12/18670	0.1667	0.4463	0.3631	GRN/CNTF/NTRK3/SCARF1/LRP1	5
BP	GO:0070601	centromeric sister chromatid cohesion	5/4749	12/18670	0.1667	0.4463	0.3631	BUB1B/BUB1/PPP2R1A/BOD1/AXIN2	5
BP	GO:0071340	skeletal muscle acetylcholine-gated channel clustering	5/4749	12/18670	0.1667	0.4463	0.3631	ETV5/DNAJA3/LRP4/DVL1/FZD9	5
BP	GO:0071472	cellular response to salt stress	5/4749	12/18670	0.1667	0.4463	0.3631	SLC25A23/MICU1/XRCC6/ZFP36L1/SLC12A6	5
BP	GO:0071639	positive regulation of monocyte chemotactic protein-1 production	5/4749	12/18670	0.1667	0.4463	0.3631	TWIST1/IL1B/CLEC7A/LGALS9/ADIPOQ	5
BP	GO:0071712	ER-associated misfolded protein catabolic process	5/4749	12/18670	0.1667	0.4463	0.3631	SDF2L1/DERL1/POMT2/VCP/SDF2	5
BP	GO:0072520	seminiferous tubule development	5/4749	12/18670	0.1667	0.4463	0.3631	KIF18A/UBB/TBC1D20/REC8/WDR48	5
BP	GO:0097340	inhibition of cysteine-type endopeptidase activity	5/4749	12/18670	0.1667	0.4463	0.3631	NOL3/BCL2L12/BIRC3/BIRC7/CARD8	5
BP	GO:0097341	zymogen inhibition	5/4749	12/18670	0.1667	0.4463	0.3631	NOL3/BCL2L12/BIRC3/BIRC7/CARD8	5
BP	GO:0097531	mast cell migration	5/4749	12/18670	0.1667	0.4463	0.3631	VEGFA/RAC1/SWAP70/RAC2/VEGFC	5
BP	GO:0098974	postsynaptic actin cytoskeleton organization	5/4749	12/18670	0.1667	0.4463	0.3631	MYH10/ACTG1/INA/WASF2/ACTB	5
BP	GO:0099550	trans-synaptic signaling, modulating synaptic transmission	5/4749	12/18670	0.1667	0.4463	0.3631	NTRK2/PLAT/SYT4/CNR1/F2R	5
BP	GO:1901387	positive regulation of voltage-gated calcium channel activity	5/4749	12/18670	0.1667	0.4463	0.3631	KCNE3/STAC3/STAC/CACNB2/EHD3	5
BP	GO:1902224	ketone body metabolic process	5/4749	12/18670	0.1667	0.4463	0.3631	HMGCL/OXCT1/OXCT2/BDH2/TYRP1	5
BP	GO:1903909	regulation of receptor clustering	5/4749	12/18670	0.1667	0.4463	0.3631	GSN/LRP4/FZD9/TGFB1/SHISA7	5
BP	GO:1904181	positive regulation of membrane depolarization	5/4749	12/18670	0.1667	0.4463	0.3631	MLLT11/TSPO/CCK/TRPM4/P2RX7	5
BP	GO:2000341	regulation of chemokine (C-X-C motif) ligand 2 production	5/4749	12/18670	0.1667	0.4463	0.3631	KLF4/TIRAP/TNF/CD74/LRP1	5
BP	GO:0001655	urogenital system development	92/4749	330/18670	0.1673	0.4472	0.3638	EGR1/CENPF/LIF/VEGFA/NOTCH1/SDC4/TP73/SULF2/CASP9/ITGA3/KANK2/CEP55/PDGFA/CTSH/TREX1/MYO1E/CYP7B1/MPV17/MMP9/TP63/PTCH1/FOXB1/CRIP1/RRM2B/BAX/DCHS1/MPST/SMAD7/CFLAR/GLIS2/ARID5B/WWTR1/KLHL3/PKD2/NID1/SMAD6/PRKX/JAG1/HOXB7/AQP2/SDC1/LRP4/WDPCP/ITGA6/GREB1L/WDR77/FEM1B/RXRA/SOX8/BASP1/TFAP2B/IFT27/NFIA/UBE3A/ACVR2B/TMED10/CA2/SOX11/YAP1/DLG5/DACT2/SMAD1/SFRP1/ADIPOQ/CD34/ESR1/UMOD/HOXA11/PYGO1/FGF8/NUP93/EAF2/STAT1/PCSK5/HPGD/ACTA2/PBX1/ARL3/ADAMTS1/DLL1/CER1/TGFB1/KIF26B/C1GALT1/HAS2/RARA/RDH10/FMN1/LAMA5/PDGFB/GATA3/ILK	92
BP	GO:0006505	GPI anchor metabolic process	11/4749	32/18670	0.1678	0.4472	0.3638	PIGK/PIGH/DPM2/PIGQ/PIGO/PIGC/PIGW/PIGM/PIGA/PIGG/PIGT	11
BP	GO:0009261	ribonucleotide catabolic process	11/4749	32/18670	0.1678	0.4472	0.3638	PDE4A/ABCD1/NUDT16/PDE4D/PDE4B/HPRT1/ENTPD4/NUDT3/AMPD3/NT5E/PDE7B	11
BP	GO:0015012	heparan sulfate proteoglycan biosynthetic process	11/4749	32/18670	0.1678	0.4472	0.3638	HS3ST3B1/HS3ST3A1/B3GAT3/CSGALNACT1/TCF7L2/B3GALT6/EXT1/EXTL2/HS6ST1/HS3ST4/XYLT1	11
BP	GO:0033006	regulation of mast cell activation involved in immune response	11/4749	32/18670	0.1678	0.4472	0.3638	FES/LGALS9/GAB2/IL4R/HMOX1/UNC13D/RAC2/RABGEF1/IL13/FER/SPHK2	11
BP	GO:0046039	GTP metabolic process	11/4749	32/18670	0.1678	0.4472	0.3638	AK3/NME4/NME3/AK4/MOCS1/IMPDH1/RAB23/AMPD3/NFS1/NME9/NME2	11
BP	GO:0051085	chaperone cofactor-dependent protein refolding	11/4749	32/18670	0.1678	0.4472	0.3638	HSPA2/HSPA5/HSPA1A/DNAJB5/HSPA9/DNAJB12/CD74/HSPA6/HSPA1L/HSPA14/DNAJB4	11
BP	GO:0060325	face morphogenesis	11/4749	32/18670	0.1678	0.4472	0.3638	CSRNP1/SKI/ASPH/PLEKHA1/MSX1/TGFB3/ARID5B/DLX5/LRP6/TGFB1/ANKRD11	11
BP	GO:0071295	cellular response to vitamin	11/4749	32/18670	0.1678	0.4472	0.3638	VDR/PPARG/KANK2/FES/GDAP1/PIM1/PHEX/CASR/CYP27B1/BGLAP/SFRP1	11
BP	GO:0090504	epiboly	11/4749	32/18670	0.1678	0.4472	0.3638	HBEGF/COL5A1/CEACAM1/MTOR/MMP12/ARHGAP35/CLASP2/WNT7A/CD44/CD151/DDR1	11
BP	GO:1904467	regulation of tumor necrosis factor secretion	11/4749	32/18670	0.1678	0.4472	0.3638	LGALS9/LILRA2/HAVCR2/IL27RA/DEFB114/SYT11/ZC3H12A/LILRA5/IFNGR1/GHRL/FZD5	11
BP	GO:0007548	sex differentiation	76/4749	270/18670	0.1682	0.4481	0.3645	VEGFA/ASPM/TYRO3/ICAM1/NTRK1/FANCG/KIF18A/TP63/HSPA5/BRCA2/BAX/NASP/PLEKHA1/HYAL3/SRC/NUDT1/NKX2-1/MERTK/ARRB1/RRM1/DMC1/RAB13/UBB/AXL/ARID5B/FGF9/BIK/SDC1/TIFAB/PATZ1/TBC1D20/GREB1L/CBX2/CENPI/MKKS/FNDC3A/BAK1/WNT7A/SOX8/BASP1/UBE3A/NCOA4/REC8/WDR19/CITED2/CEBPB/IRX5/BCL2L1/ADAM15/ZNF830/CTNNA1/RBMY1B/SFRP1/ESR1/KDM5A/TNFSF10/DMRTC2/LRP6/HOXA11/INSR/NUPR1/FGF8/ARID4A/PBX1/ADAMTS1/ATM/CDKL2/WDR48/ASB1/TMF1/RARA/CCND1/RDH10/GATA3/ERCC1/SIRT1	76
BP	GO:0019217	regulation of fatty acid metabolic process	29/4749	96/18670	0.1683	0.4482	0.3646	TWIST1/IL1B/NR4A3/PPARG/PDPR/TREX1/CEACAM1/MTOR/ABCD1/ABCD2/FABP5/CD74/TYSND1/PRKAB2/ADIPOR2/SLC45A3/INSIG1/ADIPOR1/PRKAG2/CNR1/PIBF1/ADIPOQ/CPT1A/DGAT2/ACACB/CYP7A1/GSTZ1/TRIB3/SIRT1	29
BP	GO:0031345	negative regulation of cell projection organization	54/4749	188/18670	0.1692	0.4503	0.3664	CRMP1/ITGA3/BCL11A/YWHAH/CDK5/SPP1/GORASP1/SEMA4C/CAPZB/SEMA7A/PLK2/RGMA/SEMA3G/SEMA6C/ADCY6/PFN2/MYLIP/SEMA6B/PTPN9/LGALS1/CBFA2T2/STX1B/LRP4/CARM1/FGF13/TBX6/ARHGAP4/CDK10/LRP1/THY1/UBE3A/CTSZ/SEMA3B/VIM/SEMA5B/PMP22/GSK3A/RAPGEF2/SNAPIN/RAP1GAP2/PRNP/PTPRS/ITM2C/SEMA4D/ARF6/ARHGDIA/ID1/RUFY3/SEMA5A/RTN4R/CEP97/TRPC5/GDI1/FYN	54
BP	GO:0042073	intraciliary transport	17/4749	53/18670	0.1694	0.4505	0.3665	TTC30A/WDR34/DYNLRB1/ICK/IFT122/IFT172/TTC21A/KIF3C/IFT27/WDR60/BBS12/WDR19/IFT80/ARL3/TTC26/CLUAP1/TNPO1	17
BP	GO:1903307	positive regulation of regulated secretory pathway	17/4749	53/18670	0.1694	0.4505	0.3665	CDK5/GAB2/HYAL3/IL4R/SYT4/CD177/RAB3D/RAB27A/CNR1/UNC13D/IL13/LAMP1/DOC2B/RAB15/SPHK2/CACNB2/PTAFR	17
BP	GO:0030433	ubiquitin-dependent ERAD pathway	24/4749	78/18670	0.1696	0.4507	0.3667	HSPA5/DERL1/TRIM25/SYVN1/VCP/DNAJB12/USP19/HERPUD1/NPLOC4/FBXO27/UBE4A/SGTA/UBE2G2/BCAP31/TRIM13/SEC61B/JKAMP/EDEM2/UBQLN2/TMEM67/RNF121/TMUB2/FBXO44/DNAJB2	24
BP	GO:0019048	modulation by virus of host morphology or physiology	13/4749	39/18670	0.1702	0.4519	0.3677	TYMS/KPNA2/NTRK3/SCRIB/RXRA/KPNA3/CCNK/BCL2L1/ZC3H12A/INSR/ATG7/TGFB1/BAD	13
BP	GO:0030488	tRNA methylation	13/4749	39/18670	0.1702	0.4519	0.3677	TRMT12/GTPBP3/ALKBH8/TRMT1/TARBP1/NSUN6/TRMT10B/TRMT13/TRMT112/METTL8/TRMT10C/TRMT1L/NSUN2	13
BP	GO:0001754	eye photoreceptor cell differentiation	15/4749	46/18670	0.1704	0.4519	0.3677	MYO7A/VEGFA/NTRK2/ROM1/PRDM1/CCDC66/STAT3/NKD1/TUG1/PRKCI/THY1/SOX8/AGTPBP1/TOPORS/SDK2	15
BP	GO:0002067	glandular epithelial cell differentiation	15/4749	46/18670	0.1704	0.4519	0.3677	NOTCH1/TP63/ASCL1/SPDEF/WDR77/RXRA/SIDT2/ARNTL/GSK3A/IL13/FGF8/DLL1/RARA/PDX1/BAD	15
BP	GO:0033628	regulation of cell adhesion mediated by integrin	15/4749	46/18670	0.1704	0.4519	0.3677	CXCL13/WNK1/PTPN6/PLAU/SERPINE1/SWAP70/FERMT3/MUC1/CRK/PIEZO1/ACER2/CD3E/TESC/ADAM9/RAC3	15
BP	GO:0051646	mitochondrion localization	15/4749	46/18670	0.1704	0.4519	0.3677	BRAT1/UXT/ATCAY/ATP2A1/UBB/MSTO1/KAT2A/SYNJ2BP/MAP1S/LRPPRC/RHOT2/NEFL/UCHL1/SYBU/MGARP	15
BP	GO:0006497	protein lipidation	27/4749	89/18670	0.1724	0.4557	0.3707	ZDHHC12/CLIP3/PIGK/PIGH/DPM2/NMT1/ABCA1/PIGQ/ZDHHC24/PIGO/GBA/ZDHHC3/PIGC/PIGW/PIK3C3/ZDHHC4/ZDHHC9/WDR45/ZDHHC2/ZDHHC7/PIGM/PIGA/PORCN/ZDHHC16/ATG7/PIGG/PIGT	27
BP	GO:0072001	renal system development	82/4749	293/18670	0.1726	0.4557	0.3707	EGR1/CENPF/LIF/VEGFA/NOTCH1/SDC4/TP73/SULF2/CASP9/ITGA3/KANK2/CEP55/PDGFA/CTSH/TREX1/MYO1E/MPV17/MMP9/PTCH1/RRM2B/BAX/DCHS1/MPST/SMAD7/CFLAR/GLIS2/ARID5B/WWTR1/KLHL3/PKD2/NID1/SMAD6/PRKX/JAG1/HOXB7/AQP2/SDC1/LRP4/WDPCP/ITGA6/GREB1L/SOX8/BASP1/TFAP2B/IFT27/NFIA/ACVR2B/TMED10/CA2/SOX11/YAP1/DLG5/DACT2/SMAD1/SFRP1/ADIPOQ/CD34/UMOD/HOXA11/PYGO1/FGF8/NUP93/STAT1/PCSK5/HPGD/ACTA2/PBX1/ARL3/ADAMTS1/DLL1/CER1/TGFB1/KIF26B/C1GALT1/HAS2/RARA/RDH10/FMN1/LAMA5/PDGFB/GATA3/ILK	82
BP	GO:0001822	kidney development	78/4749	278/18670	0.1728	0.4557	0.3707	EGR1/CENPF/LIF/VEGFA/NOTCH1/SDC4/TP73/SULF2/CASP9/ITGA3/KANK2/PDGFA/CTSH/TREX1/MYO1E/MPV17/MMP9/PTCH1/RRM2B/BAX/DCHS1/MPST/SMAD7/CFLAR/GLIS2/ARID5B/WWTR1/KLHL3/PKD2/NID1/SMAD6/PRKX/JAG1/HOXB7/AQP2/SDC1/LRP4/WDPCP/GREB1L/SOX8/BASP1/TFAP2B/IFT27/ACVR2B/TMED10/CA2/SOX11/YAP1/DLG5/DACT2/SMAD1/SFRP1/ADIPOQ/CD34/UMOD/HOXA11/PYGO1/FGF8/STAT1/PCSK5/HPGD/ACTA2/PBX1/ARL3/ADAMTS1/DLL1/CER1/TGFB1/KIF26B/C1GALT1/HAS2/RARA/RDH10/FMN1/LAMA5/PDGFB/GATA3/ILK	78
BP	GO:0042440	pigment metabolic process	22/4749	71/18670	0.173	0.4557	0.3707	MTHFD1L/CPOX/TRPC1/CTNS/TSPO/FXN/MYO5A/HMOX1/IBA57/HPRT1/MTHFD1/ASIP/OCA2/BDH2/APRT/BLVRA/RAPGEF2/HMOX2/PPOX/PRPS1/DDT/TYRP1	22
BP	GO:1903707	negative regulation of hemopoiesis	45/4749	155/18670	0.1732	0.4557	0.3707	NOTCH1/HMGB3/TRIB1/BCL6/CBFB/TNFSF4/CEACAM1/HMGB1/ZFP36/TLR4/PIAS3/FOXP3/CTLA4/ZBTB46/IL4R/SMAD7/HLA-G/HSPA9/LILRB4/CCL3/CD74/HLX/PGLYRP3/LAG3/TOB2/ERBB2/NFKBIA/DTX1/ZC3H12A/TMEM176B/NRARP/SFRP1/GABPA/ADIPOQ/IL4/ZFP36L1/DLL1/ZNF675/CUL4A/JAK3/RARA/ZFPM1/LDB1/TCTA/NME2	45
BP	GO:0006379	mRNA cleavage	8/4749	22/18670	0.1738	0.4557	0.3707	POLR2I/ZNRD1/ERN1/CPSF1/TUT1/CPSF6/NCBP2/CSTF3	8
BP	GO:0006582	melanin metabolic process	8/4749	22/18670	0.1738	0.4557	0.3707	TRPC1/CTNS/MYO5A/ASIP/OCA2/RAPGEF2/DDT/TYRP1	8
BP	GO:0007063	regulation of sister chromatid cohesion	8/4749	22/18670	0.1738	0.4557	0.3707	ESPL1/CDCA5/BUB1/SFPQ/FEN1/DDX11/AXIN2/SMC5	8
BP	GO:0007398	ectoderm development	8/4749	22/18670	0.1738	0.4557	0.3707	NF2/ZBTB17/SMURF1/ITGA6/EPB41L5/VPS52/STX2/VAX2	8
BP	GO:0016226	iron-sulfur cluster assembly	8/4749	22/18670	0.1738	0.4557	0.3707	FXN/HSPA9/NDOR1/IBA57/NUBP1/ISCU/NFS1/ISCA2	8
BP	GO:0018230	peptidyl-L-cysteine S-palmitoylation	8/4749	22/18670	0.1738	0.4557	0.3707	ZDHHC12/CLIP3/ZDHHC24/ZDHHC3/ZDHHC4/ZDHHC9/ZDHHC2/ZDHHC7	8
BP	GO:0018231	peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine	8/4749	22/18670	0.1738	0.4557	0.3707	ZDHHC12/CLIP3/ZDHHC24/ZDHHC3/ZDHHC4/ZDHHC9/ZDHHC2/ZDHHC7	8
BP	GO:0031163	metallo-sulfur cluster assembly	8/4749	22/18670	0.1738	0.4557	0.3707	FXN/HSPA9/NDOR1/IBA57/NUBP1/ISCU/NFS1/ISCA2	8
BP	GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane	8/4749	22/18670	0.1738	0.4557	0.3707	STX11/SNAP47/SNAP29/STX1B/STX19/SNAP23/SNAPIN/STX2	8
BP	GO:0032928	regulation of superoxide anion generation	8/4749	22/18670	0.1738	0.4557	0.3707	ACP5/CLEC7A/CD177/GNAI2/FPR2/CYBA/TYROBP/TGFB1	8
BP	GO:0042359	vitamin D metabolic process	8/4749	22/18670	0.1738	0.4557	0.3707	VDR/IL1B/TNF/SNAI1/CYP27B1/CUBN/PIAS4/CYP11A1	8
BP	GO:0044321	response to leptin	8/4749	22/18670	0.1738	0.4557	0.3707	NR4A3/CCNA2/BBS2/STAT3/MKKS/ADIPOR1/CCND1/SIRT1	8
BP	GO:0044342	type B pancreatic cell proliferation	8/4749	22/18670	0.1738	0.4557	0.3707	NR4A1/NR4A3/IGFBP4/IGFBP3/SIDT2/SFRP1/NUPR1/BAD	8
BP	GO:0046628	positive regulation of insulin receptor signaling pathway	8/4749	22/18670	0.1738	0.4557	0.3707	SORL1/SRC/PAK1/ADIPOR1/GNAI2/NUCKS1/GKAP1/SIRT1	8
BP	GO:0048305	immunoglobulin secretion	8/4749	22/18670	0.1738	0.4557	0.3707	TNFSF4/GPI/TNF/TNFRSF4/HLA-E/TRAF2/TRAF6/POU2F2	8
BP	GO:0050765	negative regulation of phagocytosis	8/4749	22/18670	0.1738	0.4557	0.3707	SIRPA/HMGB1/CD300LF/CD47/TLR2/SYT11/ADIPOQ/TGFB1	8
BP	GO:0060390	regulation of SMAD protein signal transduction	8/4749	22/18670	0.1738	0.4557	0.3707	TGFB3/WWTR1/FAM89B/SPTBN1/NUP93/RBPMS/TGFB1/VEPH1	8
BP	GO:0060487	lung epithelial cell differentiation	8/4749	22/18670	0.1738	0.4557	0.3707	KLF2/THRA/ASCL1/NKX2-1/SPDEF/RBPJ/YAP1/IL13	8
BP	GO:0071359	cellular response to dsRNA	8/4749	22/18670	0.1738	0.4557	0.3707	IFIT1/PQBP1/FLOT1/IRF3/COLEC12/RALB/ZCCHC3/P2RX7	8
BP	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus	8/4749	22/18670	0.1738	0.4557	0.3707	VEGFA/NOTCH1/RBPJ/ATF4/RUNX2/SMAD1/DLX5/SESN2	8
BP	GO:1901685	glutathione derivative metabolic process	8/4749	22/18670	0.1738	0.4557	0.3707	GSTO1/GSTM1/GSTT1/MGST2/MGST3/GSTK1/GSTZ1/AKR1A1	8
BP	GO:1901687	glutathione derivative biosynthetic process	8/4749	22/18670	0.1738	0.4557	0.3707	GSTO1/GSTM1/GSTT1/MGST2/MGST3/GSTK1/GSTZ1/AKR1A1	8
BP	GO:0071322	cellular response to carbohydrate stimulus	42/4749	144/18670	0.1741	0.4563	0.3712	ICAM1/SRF/RAC1/PIM3/CLEC7A/SMARCB1/TIAM1/ARRB1/ENY2/C2CD2L/SRI/IGF1R/MAP2K6/LGALS1/CASR/SMARCA4/TRPM4/NADK/OXCT1/LRP1/SLC26A6/PRKCE/SIDT2/LRP5L/ZNF236/CYBA/MAP2K4/BRSK2/GHRL/ERN1/RAB11FIP5/COLEC12/ZFP36L1/GCLC/PRKCB/SLC9B2/CYP7A1/NDUFAF2/PDX1/SYBU/BAD/NME2	42
BP	GO:1904064	positive regulation of cation transmembrane transport	42/4749	144/18670	0.1741	0.4563	0.3712	WNK1/HSPA2/BAX/CXCL10/TRPC1/COX17/RNF207/CCR2/ATP2A1/AMIGO1/KCNE3/SRI/KCNJ2/PKD2/HTT/CCL2/ATP1B1/KCNMB1/GSTO1/PINK1/CACNG3/STAC3/ACTN4/CXCL9/PIRT/DRD1/STAC/THY1/CD19/SUMO1/NTSR1/CHP1/PARK7/ATP1B3/LACRT/IL13/KCNH2/F2R/TESC/CACNB2/EHD3/GALR2	42
BP	GO:0036498	IRE1-mediated unfolded protein response	20/4749	64/18670	0.1762	0.4616	0.3755	ATP6V0D1/HSPA5/BAX/TPP1/PTPN1/ZBTB17/LMNA/SYVN1/EXTL2/PARP16/BAK1/FICD/GSK3A/KLHDC3/YIF1A/DDX11/ERN1/SERP1/TMEM33/SHC1	20
BP	GO:0051279	regulation of release of sequestered calcium ion into cytosol	25/4749	82/18670	0.1765	0.4616	0.3756	PTPN6/JSRP1/BAX/CXCL10/TRPC1/MYO5A/PDE4D/SRI/PKD2/HTT/GSTO1/CORO1A/CXCL9/DRD1/FKBP1A/THY1/CD19/NTSR1/PRKCE/CYBA/LACRT/IL13/CAMK2D/F2R/TGFB1	25
BP	GO:0097581	lamellipodium organization	25/4749	82/18670	0.1765	0.4616	0.3756	FSCN1/ABLIM1/RAC1/CYFIP1/CORO1C/CAPZB/SRGAP2/CTTN/MTOR/SRC/CORO1B/S1PR1/VAV2/TWF2/PARVB/ARPC5/CD44/RAC2/FER/ABLIM2/WASF2/WHAMM/CDC42/WAS/SPATA13	25
BP	GO:1905954	positive regulation of lipid localization	25/4749	82/18670	0.1765	0.4616	0.3756	IL1B/ABCG1/ANXA2P2/PRELID1/SPP1/PTCH1/ANXA2/FITM2/FITM1/MAP2K6/ABCA1/LRP1/NTSR1/ABCB4/NFKBIA/ZC3H12A/GHRL/ADIPOQ/LDLRAP1/ACACB/TNFSF11/TMF1/P2RX7/SREBF2/SIRT1	25
BP	GO:0098727	maintenance of cell number	46/4749	159/18670	0.177	0.4627	0.3765	LIF/NOTCH1/ASPM/KLF4/SPI1/TP63/SMC3/SKI/STAT3/PELO/SETD6/RBPJ/PRDM16/FOXO1/ZFP36L2/JAG1/DIS3L2/SALL4/CNOT3/EZH2/FANCC/SS18/GNL3/WNT7A/ZHX2/POLR2I/ARID1A/VPS72/MMP24/POLR2C/YAP1/KLF10/ELAVL1/SFRP1/POLR2J/SMC1A/MED12/PBX1/LBH/MCPH1/DLL1/KDM4C/MED28/CUL4A/POLR2A/LDB1	46
BP	GO:0002440	production of molecular mediator of immune response	80/4749	286/18670	0.1774	0.4635	0.3771	IL1B/IL18/NR4A3/NLRP3/IL10/BATF/IL1R1/EXO1/BCL6/HK1/TREX1/TNFSF4/TFRC/MZB1/GALNT2/GPI/TNF/MSH6/TNFRSF4/SEMA7A/TLR4/FOXP3/ITM2A/PMS2P1/IL4R/RSAD2/SMAD7/FFAR2/SWAP70/CCR6/CCR2/HMOX1/HLA-G/TP53BP1/BTK/BST2/TGFB3/CD74/POLQ/TRIL/FFAR3/IRAK3/PTPRC/TRPM4/HLA-E/TLR2/SUPT6H/NOD2/AICDA/IL27RA/RNF8/ARG1/IL18R1/MR1/PMS2P5/IL7R/APLF/SAMHD1/POLM/IL13/TRAF2/CARD11/TNFSF13/IL4/TNFRSF1B/MAD2L2/KLK5/TRAF6/SPHK2/FZD5/ATM/POU2F2/TGFB1/JAK3/CD96/GATA3/ERCC1/RNF168/KLK3/SIRT1	80
BP	GO:0034329	cell junction assembly	68/4749	241/18670	0.1776	0.4638	0.3773	PLEC/VEGFA/SDC4/FSCN1/ITGA2/SRF/RAC1/CBFB/CORO1C/CD9/TNF/CTTN/ACTG1/SMAD7/SRC/SNAI1/TRIP6/RAB13/LIMS1/MPP7/GJD3/PRKCA/MPP5/CLASP2/WDPCP/VASP/PRKCI/LIMCH1/ITGA6/ACTN4/DUSP22/PKP4/FLOT1/S100A10/LRP1/THY1/CAPZA1/RAPGEF1/EPB41L5/CDH26/CD151/ECT2/WDR1/CDH9/PARD6G/ZNF703/CTNNA1/RAPGEF2/DLG5/SFRP1/ARVCF/PARD6B/APC/BCR/PARD6A/ARL2/FZD5/WHAMM/PIP5K1A/BCAS3/CDC42/CDH5/FMN1/LAMA5/LDB1/ILK/ACTB/GJA5	68
BP	GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	68/4749	241/18670	0.1776	0.4638	0.3773	SKIL/CD109/NOTCH1/TTK/ITGA3/CDKN2B/LRG1/PMEPA1/SNX25/TGFB1I1/HSPA5/HSPA1A/SKI/TMPRSS6/MSX1/DAND5/SMAD7/SORL1/NKX2-1/NUMA1/SDCBP/GREM2/PELO/UBB/SFRP4/TGFB3/WWTR1/FGF9/RBPJ/ZC3H3/PRDM16/SMAD6/RPS27A/SMURF1/FAM89B/SPTBN1/UBA52/LEMD3/FKBP1A/VASN/GDF7/LDLRAD4/TFAP2B/FKBP8/ACVR2B/RBPMS2/EID2/CITED2/SOX11/ZNF703/HTRA4/DACT2/SFRP1/LEFTY1/BMP10/BMP3/FBXL15/NUP93/RBPMS/CER1/HTRA1/TGFB1/ZNF451/CDH5/VEPH1/MIR17HG/ILK/SIRT1	68
BP	GO:0006903	vesicle targeting	28/4749	93/18670	0.1785	0.4661	0.3792	SEC13/GORASP1/SEC24D/MCFD2/F5/STX5/SEC16A/CNIH2/SNAP29/ANKRD28/TBC1D20/CLASP2/SCRIB/CEP19/TMED9/SNAP23/GBF1/TMED10/CTSZ/WDR11/TRAPPC4/RAB1A/AP1AR/PPP6C/PEF1/PPP6R1/RAB1B/USO1	28
BP	GO:0046425	regulation of JAK-STAT cascade	40/4749	137/18670	0.1791	0.4672	0.3801	LIF/NOTCH1/IL18/CSF2/IL21/CSF1R/IL10/DOT1L/BCL3/TNFRSF18/CNTF/CDK5/NF2/PPP2R1A/SOCS2/TNF/STAT3/PARP14/SOCS3/FLT3/PTK6/PTPRC/PPP2CA/ADIPOR1/IL26/OSM/HGS/GGNBP2/PIBF1/CNOT7/IL13/IL20/IL4/ARL2BP/F2R/CRLF3/IL10RA/JAK3/FYN/IL23A	40
BP	GO:0071398	cellular response to fatty acid	18/4749	57/18670	0.1791	0.4672	0.3801	PPARG/TNFSF4/E2F1/LDLR/FFAR2/CCNB1/SRC/PTGER4/ADCY6/FFAR3/PRKCE/PTGER2/ZC3H12A/SFRP1/CPT1A/DGAT2/PTAFR/NME2	18
BP	GO:0046928	regulation of neurotransmitter secretion	31/4749	104/18670	0.1796	0.4683	0.381	ADORA2A/RIMS3/CDK5/SYN1/NCS1/CHRNA5/HCRT/P2RX1/SYT4/HTR2A/CAMK2A/PFN2/APBA2/STX1B/DVL1/DRD1/DTNBP1/WNT7A/CNR1/FMR1/SYT11/TACR2/SNAPIN/NAPB/MCTP2/KCNC4/CHRNA3/PRKCB/P2RY1/CACNB2/FBXL20	31
BP	GO:0051283	negative regulation of sequestering of calcium ion	37/4749	126/18670	0.1797	0.4685	0.3811	PTPN6/CHERP/JSRP1/NOL3/BAX/CXCL10/TRPC1/MYO5A/PDE4D/HTR2A/CCL3/SRI/PKD2/CCR5/HTT/GSTO1/TPCN1/PTPRC/CORO1A/RASA3/ANXA5/CXCL9/DRD1/FKBP1A/DDIT3/THY1/CD19/NTSR1/PRKCE/CYBA/LACRT/IL13/CAMK2D/F2R/PLCB1/TGFB1/P2RX7	37
BP	GO:0043270	positive regulation of ion transport	77/4749	275/18670	0.1799	0.4686	0.3812	IL1B/WNK1/ADORA2A/HSPA2/CCR1/ANXA2P2/LGALS3/PRELID1/BAX/CXCL10/TRPC1/COX17/LILRA2/ANXA2/TSPO/RNF207/CCR2/HCRT/SCN1B/P2RX1/HOMER1/ABAT/SYT4/ATP2A1/CCL3/CAMK2A/AMIGO1/KCNE3/SRI/KCNJ2/PKD2/ATF4/MAP2K6/HTT/CCL2/CCK/ATP1B1/CASR/KCNMB1/GSTO1/PINK1/CACNG3/STAC3/ACTN4/CXCL9/BAK1/PIRT/DRD1/STAC/THY1/CD19/SUMO1/NTSR1/CHP1/PARK7/ATP1B3/ABCB4/TACR2/CEBPB/LILRA5/LACRT/MLLT6/IL13/KCNH2/P2RX5/F2R/TESC/P2RY1/SPHK2/CACNB2/TNFSF11/EHD3/FFAR1/GALR2/PDGFB/PTAFR/P2RX7	77
BP	GO:0006023	aminoglycan biosynthetic process	34/4749	115/18670	0.18	0.4686	0.3812	IL1B/B3GNT5/SDC4/HS3ST3B1/HS3ST3A1/CHST15/GPC1/CHPF2/B3GAT3/OGN/CSGALNACT1/SDC2/SLC35D2/SLC35D1/SDC1/B3GALT6/B3GNT2/CHST7/EXT1/EXTL2/GPC2/DSEL/ST3GAL3/HS6ST1/HAS3/CHPF/B4GALT5/CHST13/XYLT1/TGFB1/HAS2/PDGFB/B4GALT4/B4GALT7	34
BP	GO:0001960	negative regulation of cytokine-mediated signaling pathway	23/4749	75/18670	0.1805	0.4689	0.3814	PPARG/IL1RN/TREX1/RFFL/NOL3/MMP12/IL1R2/PARP14/TRAIP/IRAK3/PTPRC/SIGIRR/SCRIB/ARG1/SAMHD1/RABGEF1/CNOT7/YTHDF3/PADI2/PIAS4/ADIPOQ/CARD8/ZNF675	23
BP	GO:0006929	substrate-dependent cell migration	10/4749	29/18670	0.1806	0.4689	0.3814	ITGA2/TNFRSF12A/MYH10/CTTN/SDCBP/FMNL1/PTPRC/EPB41L5/CD2AP/VEGFC	10
BP	GO:0031116	positive regulation of microtubule polymerization	10/4749	29/18670	0.1806	0.4689	0.3814	FES/RAC1/HSPA1A/PSRC1/NUMA1/PAK1/RPS3/TERF1/ARL2/SLAIN2	10
BP	GO:0035666	TRIF-dependent toll-like receptor signaling pathway	10/4749	29/18670	0.1806	0.4689	0.3814	IRF7/TLR4/UBB/RPS27A/CD300LF/UBA52/TANK/TLR6/IRF3/BIRC3	10
BP	GO:0044068	modulation by symbiont of host cellular process	10/4749	29/18670	0.1806	0.4689	0.3814	GAPDH/KPNA2/NTRK3/SCRIB/KPNA3/CCNK/BCL2L1/ZC3H12A/ATG7/BAD	10
BP	GO:0070229	negative regulation of lymphocyte apoptotic process	10/4749	29/18670	0.1806	0.4689	0.3814	AURKB/BCL6/DOCK8/CD74/IL7R/IDO1/TSC22D3/SLC39A10/JAK3/MIR17HG	10
BP	GO:1900027	regulation of ruffle assembly	10/4749	29/18670	0.1806	0.4689	0.3814	ICAM1/CYFIP1/CORO1C/RHOG/SH3YL1/PFN2/EPS8L2/WDPCP/PLEKHM1/USP17L2	10
BP	GO:0014009	glial cell proliferation	16/4749	50/18670	0.1815	0.471	0.3832	IL1B/NOTCH1/CSF1R/NF2/TNF/CSF1/E2F1/SKI/MTOR/TSPO/ETV5/CLU/PRKCI/LTA/SOX11/DICER1	16
BP	GO:0048762	mesenchymal cell differentiation	62/4749	219/18670	0.1823	0.4729	0.3848	TWIST1/IL1B/NOTCH1/FAM83D/TGFB1I1/CORO1C/SEMA4C/SEMA7A/MTOR/MSX1/SMAD7/SEMA3G/PDCD4/SNAI1/NKX2-1/ALX1/TIAM1/SEMA6C/TRIM62/SDCBP/TGFB3/WWTR1/RBPJ/SEMA6B/EFNB1/CYP26C1/JAG1/FAM172A/CLASP2/CFL1/EZH2/PPP2CA/ADIPOR1/NOLC1/VASN/SOX8/LDLRAD4/DDX17/EPB41L5/SOX11/SEMA3B/ADAM15/ZNF703/SEMA5B/DLG5/PHLDB1/SFRP1/GLIPR2/MAD2L2/LRP6/SEMA4D/FGF8/STAT1/AXIN2/TGFB1/SEMA5A/HAS2/MAPK1/RDH10/PEF1/LAMA5/AMELX	62
BP	GO:0001953	negative regulation of cell-matrix adhesion	14/4749	43/18670	0.1829	0.4731	0.3849	BCL6/CORO1C/NF2/SERPINE1/MMP12/SRC/JAG1/CLASP2/DUSP22/CDKN2A/LRP1/ACER2/ADAM15/BCAS3	14
BP	GO:0032924	activin receptor signaling pathway	14/4749	43/18670	0.1829	0.4731	0.3849	SKI/DAND5/SMAD7/FGF9/ZC3H3/LEMD3/FKBP1A/GDF7/ACVR1C/ACVR2B/CITED2/DACT2/BMP10/CER1	14
BP	GO:0038202	TORC1 signaling	14/4749	43/18670	0.1829	0.4731	0.3849	SEC13/DYRK3/MTOR/ITFG2/SIK3/C12orf66/NPRL3/CARD11/KLHL22/ATM/RRAGB/SESN2/SEH1L/MLST8	14
BP	GO:0051293	establishment of spindle localization	14/4749	43/18670	0.1829	0.4731	0.3849	ESPL1/SAPCD2/CENPA/GPSM2/NUSAP1/PLK1/NUMA1/NDC80/ARHGEF2/HTT/MYH9/ACTR1A/NSFL1C/MCPH1	14
BP	GO:0086004	regulation of cardiac muscle cell contraction	14/4749	43/18670	0.1829	0.4731	0.3849	DSC2/RANGRF/RNF207/PDE4D/ATP2A1/KCNE3/PDE4B/SRI/KCNJ2/FGF13/TRPM4/SUMO1/CAMK2D/GJA5	14
BP	GO:1901985	positive regulation of protein acetylation	14/4749	43/18670	0.1829	0.4731	0.3849	LIF/IL1B/CAMK1/FOXP3/SMARCB1/NAP1L2/ARRB1/KAT2A/MUC1/ARNTL/TADA2A/SPHK2/TGFB1/GATA3	14
BP	GO:1901099	negative regulation of signal transduction in absence of ligand	12/4749	36/18670	0.1829	0.4731	0.3849	IL1B/CSF2/MCL1/TNF/HSPA1A/IFI6/EYA2/STRADB/BCL2L1/IL7/CTNNA1/FYN	12
BP	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	12/4749	36/18670	0.1829	0.4731	0.3849	IL1B/CSF2/MCL1/TNF/HSPA1A/IFI6/EYA2/STRADB/BCL2L1/IL7/CTNNA1/FYN	12
BP	GO:0030101	natural killer cell activation	26/4749	86/18670	0.1831	0.4733	0.3851	IL18/TYRO3/PRDM1/ULBP2/RAET1E/TOX/MERTK/HAVCR2/AXL/IL21R/PGLYRP3/PTPRC/CORO1A/HLA-E/MICA/IL18R1/RAB27A/RHBDD3/UNC13D/PIBF1/LAMP1/ULBP1/TYROBP/KLRK1/PRDX1/IL23A	26
BP	GO:0009411	response to UV	41/4749	141/18670	0.1833	0.4738	0.3854	AURKB/PBK/CDKN1A/DTL/CASP9/BCL3/TREX1/UBE2A/CDC25A/PML/DDB2/MSH6/CRIP1/BRCA2/BAX/UBE2B/FEN1/GPX1/HYAL3/RPL26/BMF/ATF4/CIRBP/ZRANB3/N4BP1/ERCC8/BAK1/TP53INP1/ERCC5/FMR1/ERCC2/CHEK1/GTF2H2/RBL2/ATR/XPA/WRN/CCND1/ERCC1/TIPIN/SIRT1	41
BP	GO:0006399	tRNA metabolic process	55/4749	193/18670	0.1838	0.4747	0.3862	GTF3C4/TSEN2/QTRT1/TRMT12/FAM98B/CTU1/GTPBP3/TSEN15/ALKBH8/NARS2/TRMT1/POP5/GTF3C2/OSGEPL1/ELP5/TARBP1/PUS1/NSUN6/TRMT10B/TSEN34/PPA2/PRORSD1P/ELAC1/SEPHS1/YARS2/TRMT13/TRPT1/TYW1B/TRIT1/ELP4/EXOSC2/TRMT112/PUSL1/METTL8/LARS2/MARS2/DUS1L/DTD2/KTI12/MTFMT/HARS2/CPSF1/VARS2/TRMT10C/GTF3C6/C9orf64/RPP30/TRMT1L/THG1L/NSUN2/TRNT1/EXOSC9/FARSA/CDKAL1/PUS10	55
BP	GO:0042157	lipoprotein metabolic process	38/4749	130/18670	0.1843	0.4757	0.387	ZDHHC12/LDLR/APOL5/CLIP3/PIGK/APOL4/PPT1/PIGH/DPM2/NMT1/LYPLAL1/ABCA1/PIGQ/ZDHHC24/PIGO/LRP1/GBA/CTSD/ZDHHC3/PIGC/APOL1/PIGW/PIK3C3/ZDHHC4/DGAT2/ZDHHC9/WDR45/ZDHHC2/ZDHHC7/PIGM/APOL6/PIGA/PORCN/ATM/ZDHHC16/ATG7/PIGG/PIGT	38
BP	GO:0010771	negative regulation of cell morphogenesis involved in differentiation	29/4749	97/18670	0.1845	0.4757	0.387	YWHAH/CDK5/CORO1C/SPP1/GORASP1/SEMA4C/SEMA7A/SEMA3G/SEMA6C/SEMA6B/LRP4/FGF13/ARHGAP4/ACTN4/THY1/UBE3A/SEMA3B/SEMA5B/RAPGEF2/PTPRS/SEMA4D/ARHGDIA/AP1AR/ID1/RUFY3/SEMA5A/RTN4R/TRPC5/GDI1	29
BP	GO:0045806	negative regulation of endocytosis	21/4749	68/18670	0.1845	0.4757	0.387	RAC1/SIRPA/LGALS3/HMGB1/SDCBP/UNC119/STX1B/CD300LF/LRPAP1/CD47/TLR2/SYT11/SNX33/RABGEF1/UBQLN2/ADIPOQ/LRSAM1/PACSIN1/ARF6/TGFB1/DLG4	21
BP	GO:0071230	cellular response to amino acid stimulus	21/4749	68/18670	0.1845	0.4757	0.387	NTRK2/BCL11A/TNF/CYBB/MTOR/AMIGO1/COL6A1/SLC38A9/SH3BP4/CEBPB/BCL2L1/CYBA/UBR2/LAMTOR4/GCLC/CPEB1/LAMTOR2/KLHL22/RRAGB/SESN2/FYN	21
BP	GO:0090276	regulation of peptide hormone secretion	59/4749	208/18670	0.1846	0.4759	0.3872	IL1B/RAC1/PIM3/SLC16A1/TNF/BLK/FFAR2/TIAM1/ABAT/ARRB1/ENY2/C2CD2L/SRI/ENHO/PER2/FFAR3/CASR/TCF7L2/PRKCA/TRPM4/NADK/ANXA5/OXCT1/PFKFB2/PSMD9/LRP1/CACNA2D2/SIRT3/ILDR1/CNR1/TFAP2B/ACVR1C/SLC25A5/PRKCE/SIDT2/LRP5L/ARNTL/GLUD1/BRSK2/SFRP1/GHRL/KCNG2/CPT1A/ARL2BP/SERP1/DOC2B/SLC25A4/PFKL/TNFSF11/ARL2/NPFF/PPARD/SLC9B2/FFAR1/NDUFAF2/PDX1/GIPR/SYBU/BAD	59
BP	GO:0001952	regulation of cell-matrix adhesion	35/4749	119/18670	0.1849	0.4764	0.3876	VEGFA/SDC4/RAC1/BCL6/CORO1C/NF2/CSF1/PLAU/NINJ1/SERPINE1/MMP12/SRC/LIMS1/JAG1/CLASP2/WDPCP/PLEKHA2/LIMCH1/DUSP22/S100A10/CDKN2A/LRP1/THY1/EPB41L5/ACER2/MINK1/ADAM15/DDR1/CD3E/SFRP1/UTRN/BCAS3/FMN1/LDB1/ILK	35
BP	GO:2000278	regulation of DNA biosynthetic process	32/4749	108/18670	0.185	0.4765	0.3876	AURKB/CDKN1A/PPARG/KLF4/NEK2/PARM1/SMG5/SRC/PIF1/RFC2/CCT5/PAK3/TERF1/DSCC1/TNKS2/ACD/CTC1/CHTF8/POT1/WRAP53/ADIPOQ/SMG6/ATR/TINF2/ATM/MAPK1/PDGFB/KCNK2/FBXO4/TERF2/CCT3/DUSP1	32
BP	GO:0007096	regulation of exit from mitosis	7/4749	19/18670	0.1869	0.4791	0.3897	ANLN/CDCA5/UBE2C/SIRT2/CDC14B/PPP1R9B/TGFB1	7
BP	GO:0010888	negative regulation of lipid storage	7/4749	19/18670	0.1869	0.4791	0.3897	PPARG/ABCG1/TNF/ABCA1/NFKBIA/TTC39B/PPARD	7
BP	GO:0016082	synaptic vesicle priming	7/4749	19/18670	0.1869	0.4791	0.3897	SNAP47/SNAP29/STX1B/SNAP23/ERC2/NAPB/SV2A	7
BP	GO:0032930	positive regulation of superoxide anion generation	7/4749	19/18670	0.1869	0.4791	0.3897	CLEC7A/CD177/GNAI2/FPR2/CYBA/TYROBP/TGFB1	7
BP	GO:0034471	ncRNA 5'-end processing	7/4749	19/18670	0.1869	0.4791	0.3897	POP5/NOP14/UTP20/ABT1/TRMT10C/RPP30/THG1L	7
BP	GO:0036303	lymph vessel morphogenesis	7/4749	19/18670	0.1869	0.4791	0.3897	VEGFA/PTPN14/VASH1/ACVR2B/LGALS8/FLT4/VEGFC	7
BP	GO:0045414	regulation of interleukin-8 biosynthetic process	7/4749	19/18670	0.1869	0.4791	0.3897	KLF4/BCL3/TLR8/CLEC7A/TNF/TLR4/CD74	7
BP	GO:0060149	negative regulation of posttranscriptional gene silencing	7/4749	19/18670	0.1869	0.4791	0.3897	PPARG/ZC3H12A/NEAT1/ELAVL1/ESR1/TGFB1/NCOR1	7
BP	GO:0060716	labyrinthine layer blood vessel development	7/4749	19/18670	0.1869	0.4791	0.3897	PLCD3/VASH1/RBPJ/GGNBP2/HS6ST1/FZD5/MAPK1	7
BP	GO:0060967	negative regulation of gene silencing by RNA	7/4749	19/18670	0.1869	0.4791	0.3897	PPARG/ZC3H12A/NEAT1/ELAVL1/ESR1/TGFB1/NCOR1	7
BP	GO:0071731	response to nitric oxide	7/4749	19/18670	0.1869	0.4791	0.3897	CCNA2/CFLAR/CDK2/FOXO1/CRK/TRAF2/MTR	7
BP	GO:0098581	detection of external biotic stimulus	7/4749	19/18670	0.1869	0.4791	0.3897	CLEC7A/TLR4/CD1D/PGLYRP3/TLR2/NOD2/TLR6	7
BP	GO:0007040	lysosome organization	19/4749	61/18670	0.1882	0.4822	0.3923	MYO7A/TREX1/GRN/TPP1/PPT1/HPS4/CORO1A/TMEM106B/ABCA1/GBA/TMEM175/HOOK2/TFEB/SNAPIN/CLVS1/HEXB/RAB34/CCDC115/P2RX7	19
BP	GO:0080171	lytic vacuole organization	19/4749	61/18670	0.1882	0.4822	0.3923	MYO7A/TREX1/GRN/TPP1/PPT1/HPS4/CORO1A/TMEM106B/ABCA1/GBA/TMEM175/HOOK2/TFEB/SNAPIN/CLVS1/HEXB/RAB34/CCDC115/P2RX7	19
BP	GO:0030641	regulation of cellular pH	27/4749	90/18670	0.1894	0.485	0.3946	GRN/ATP6V0D1/SLC4A2/ATP6V0B/SLC4A3/ATP6V1E1/PPT1/ATP6V0C/SLC9A7/SLC4A11/ATP6V1A/ROGDI/SLC26A6/SLC4A10/TMEM175/CHP1/CA2/RAB38/SNAPIN/ATP6V1G1/SLC9B1/DMXL1/ATP6V1E2/DMXL2/CCDC115/MAPK1/SLC9A6	27
BP	GO:0050830	defense response to Gram-positive bacterium	30/4749	101/18670	0.1902	0.4858	0.3952	NLRP3/ACP5/TIRAP/GBP2/TNF/CARD9/RNASE8/HAVCR2/LYZ/MPEG1/PGLYRP3/HLA-E/ROMO1/TLR2/IL27RA/LCE3C/LTA/DEFB114/RNASE6/RARRES2/PLA2G2A/RIPK2/RPL39/DEFA1B/KRT6A/DEFA4/GBP4/KLRK1/P2RX7/SEH1L	30
BP	GO:0002065	columnar/cuboidal epithelial cell differentiation	33/4749	112/18670	0.1902	0.4858	0.3952	MYO7A/NOTCH1/JAG2/CDKN1A/TP63/PRDM1/TYMS/ASCL1/SERPINE1/SPDEF/RBPJ/FAM20C/CBFA2T2/PTK6/JAG1/WDPCP/TRIOBP/SCRIB/WDR77/RXRA/CEBPB/SIDT2/STRC/SOX11/ARNTL/GSK3A/IL13/FGF8/DLL1/C1GALT1/RARA/PDX1/BAD	33
BP	GO:0043279	response to alkaloid	33/4749	112/18670	0.1902	0.4858	0.3952	PPARG/ICAM1/ADORA2A/CCNA2/CDK5/FOSB/HSPA5/DHODH/MAP1LC3A/PEA15/MTOR/HOMER2/RAD51/TIAM1/HOMER1/ABAT/EFTUD2/HTR2A/UQCRC1/AIF1/RECQL5/DRD1/CNR1/PPP5C/UBE3A/TMED10/PRKCE/BCL2L1/MBD1/PPP1R9B/NPFF/ATG7/PDX1	33
BP	GO:0051817	modification of morphology or physiology of other organism involved in symbiotic interaction	33/4749	112/18670	0.1902	0.4858	0.3952	CSF1R/GAPDH/ANXA2P2/TYMS/SMC3/KPNA2/ANXA2/SMARCB1/CCL3/NTRK3/SMARCA4/TBC1D20/CFL1/SCRIB/SP1/ARG1/RXRA/JUN/FMR1/KPNA3/TAF11/CCNK/ZNF639/BCL2L1/ZC3H12A/DEFA1B/KRT6A/INSR/STOM/NUCKS1/ATG7/TGFB1/BAD	33
BP	GO:1903510	mucopolysaccharide metabolic process	33/4749	112/18670	0.1902	0.4858	0.3952	IL1B/CHST15/GLB1/CHPF2/HYAL3/IDS/PIM1/OGN/CSGALNACT1/IDUA/SLC35D2/SLC35D1/ITIH3/B3GALT6/B3GNT2/SPOCK3/CHST7/CHP1/CD44/DSEL/ST3GAL3/HAS3/CHPF/B4GALT5/HEXB/GUSB/CHST13/XYLT1/ITIH6/TGFB1/HAS2/PDGFB/B4GALT4	33
BP	GO:1990748	cellular detoxification	33/4749	112/18670	0.1902	0.4858	0.3952	TXNDC17/ALOX5AP/TNF/GPX1/PRDX3/PRDX5/HBA2/NQO1/DHFR/GSTO1/NXN/FANCC/IPCEF1/TP53INP1/GPX4/PARK7/TXNRD3/GSTM1/MPO/HBG1/PRDX6/GSTT1/HBB/MGST2/NNT/MGST3/GSTK1/CCS/TXNRD2/GSTZ1/SESN2/AKR1A1/PRDX1	33
BP	GO:0043392	negative regulation of DNA binding	17/4749	54/18670	0.1917	0.489	0.3978	NEK2/E2F1/MSX1/HMOX1/SRI/SUMO3/ENHO/PER2/DDIT3/SUMO1/JUN/NFKBIA/SOX11/IFI16/MAD2L2/ZNF675/ID1	17
BP	GO:0045747	positive regulation of Notch signaling pathway	17/4749	54/18670	0.1917	0.489	0.3978	NOTCH1/JAG2/TSPAN5/TP63/ASCL1/MAML1/STAT3/ERH/MAML2/RBPJ/ENHO/JAG1/PRKCI/NOD2/AAK1/POGLUT1/DLL1	17
BP	GO:0061005	cell differentiation involved in kidney development	17/4749	54/18670	0.1917	0.489	0.3978	LIF/NOTCH1/MYO1E/MMP9/PTCH1/GLIS2/WWTR1/PRKX/JAG1/BASP1/YAP1/ADIPOQ/CD34/STAT1/ACTA2/PDGFB/GATA3	17
BP	GO:0038034	signal transduction in absence of ligand	22/4749	72/18670	0.1923	0.4901	0.3988	IL1B/CSF2/CASP9/MCL1/PPP2R1A/TNF/HSPA1A/BAX/IFI6/MOAP1/EYA2/STRADB/BCL2A1/BAK1/WWOX/BCL2L1/BAG3/IL7/CTNNA1/GSK3A/BAD/FYN	22
BP	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand	22/4749	72/18670	0.1923	0.4901	0.3988	IL1B/CSF2/CASP9/MCL1/PPP2R1A/TNF/HSPA1A/BAX/IFI6/MOAP1/EYA2/STRADB/BCL2A1/BAK1/WWOX/BCL2L1/BAG3/IL7/CTNNA1/GSK3A/BAD/FYN	22
BP	GO:0071248	cellular response to metal ion	54/4749	190/18670	0.1924	0.4902	0.3988	RASGRP2/PPIF/WNK1/CPNE7/ALOX5AP/MMP9/FOSB/HSPA5/GSN/CYBB/MAP1LC3A/MT1E/SLC25A23/MT2A/TSPO/CCNB1/HMOX1/SYT4/ATP13A2/CPNE5/PKD2/ATF4/NQO1/AQP2/MT1X/ANXA5/MT1H/HVCN1/SUMO1/MT1G/JUN/PPP5C/RASA4/ACER1/SYT11/ECT2/RASAL1/CLIC4/BRAF/EIF2AK3/CAMK2D/PRNP/MT1A/MT1B/MT1M/NCF1/CPNE4/FOS/OGG1/SYT15/MAPK1/SLC40A1/MT1F/DLG4	54
BP	GO:0018198	peptidyl-cysteine modification	15/4749	47/18670	0.1946	0.4931	0.4012	GAPDH/ZDHHC12/PRDX3/CLIP3/RAB3D/ZDHHC24/ATP2B4/PARK7/ZDHHC3/S100A8/ZDHHC4/ZDHHC9/ZDHHC2/ZDHHC7/CHCHD4	15
BP	GO:0030261	chromosome condensation	15/4749	47/18670	0.1946	0.4931	0.4012	CDCA5/NCAPG/CDK1/TOP2A/NUSAP1/NCAPD2/CCNB1/BANF1/NCAPH/PHF13/DFFB/CHMP1A/NCAPH2/MCPH1/PHF23	15
BP	GO:0047496	vesicle transport along microtubule	15/4749	47/18670	0.1946	0.4931	0.4012	KIF23/KIF1C/BLOC1S6/BLOC1S1/CNIH2/HTT/FYCO1/BLOC1S4/AP3D1/DTNBP1/AP3M2/SNAPIN/RAB1A/AP3B2/SYBU	15
BP	GO:0070169	positive regulation of biomineral tissue development	15/4749	47/18670	0.1946	0.4931	0.4012	ISG15/WNT10B/FBXO5/TGFB3/ATF4/FAM20C/ATRAID/AMTN/ACVR2B/CEBPB/FZD9/TMEM119/TGFB1/AMELX/P2RX7	15
BP	GO:2000107	negative regulation of leukocyte apoptotic process	15/4749	47/18670	0.1946	0.4931	0.4012	AURKB/IRF7/BCL6/DOCK8/MERTK/AXL/CD74/CCR5/NOD2/IL7R/IDO1/TSC22D3/SLC39A10/JAK3/MIR17HG	15
BP	GO:0006346	methylation-dependent chromatin silencing	9/4749	26/18670	0.1947	0.4931	0.4012	MBD2/MORC2/ZNF304/AICDA/HELLS/MBD1/PPHLN1/SETDB1/SIRT1	9
BP	GO:0030206	chondroitin sulfate biosynthetic process	9/4749	26/18670	0.1947	0.4931	0.4012	CHST15/CHPF2/CSGALNACT1/SLC35D1/B3GALT6/CHST7/CHPF/CHST13/XYLT1	9
BP	GO:0033561	regulation of water loss via skin	9/4749	26/18670	0.1947	0.4931	0.4012	SRF/TP63/FA2H/SFN/STMN1/GBA/ACER1/ELOVL1/CLDN4	9
BP	GO:0048843	negative regulation of axon extension involved in axon guidance	9/4749	26/18670	0.1947	0.4931	0.4012	SEMA4C/SEMA7A/SEMA3G/SEMA6C/SEMA6B/SEMA3B/SEMA5B/SEMA4D/SEMA5A	9
BP	GO:0050926	regulation of positive chemotaxis	9/4749	26/18670	0.1947	0.4931	0.4012	VEGFA/ITGA2/CCR4/NTRK3/S1PR1/CASR/F3/NTF3/VEGFC	9
BP	GO:0051875	pigment granule localization	9/4749	26/18670	0.1947	0.4931	0.4012	MYO7A/BBS2/MYO5A/BLOC1S6/VPS33B/MKKS/RAB27A/ASIP/RAB1A	9
BP	GO:0071624	positive regulation of granulocyte chemotaxis	9/4749	26/18670	0.1947	0.4931	0.4012	RAC1/TIRAP/DAPK2/CD74/C3AR1/RAC2/C1QBP/THBS4/IL23A	9
BP	GO:0097066	response to thyroid hormone	9/4749	26/18670	0.1947	0.4931	0.4012	GAS2L1/CTSH/ANXA2/CTSB/ANXA5/KLF9/GBA/GCLC/CRLS1	9
BP	GO:1903203	regulation of oxidative stress-induced neuron death	9/4749	26/18670	0.1947	0.4931	0.4012	NR4A3/IL10/MCL1/TLR4/ATF4/PINK1/TLR6/PARK7/ATG7	9
BP	GO:1904353	regulation of telomere capping	9/4749	26/18670	0.1947	0.4931	0.4012	AURKB/NEK2/TNKS2/XRCC1/SMG6/ATM/MAPK1/ERCC1/TERF2	9
BP	GO:0006304	DNA modification	34/4749	116/18670	0.1952	0.4941	0.402	SPI1/TREX1/APOBEC3H/MPG/USP9X/APOBEC3B/ALKBH2/TDRD9/PARP2/MBD2/GNAS/PRMT7/HEMK1/PICK1/ALKBH5/N6AMT1/EZH2/AICDA/MTRR/METTL4/MAPT-AS1/TDRD5/ASZ1/BAZ2A/MBD1/NEIL1/FOS/OGG1/MGMT/MUTYH/GATA3/ALKBH3/ZFP57/PIWIL4	34
BP	GO:0021987	cerebral cortex development	34/4749	116/18670	0.1952	0.4941	0.402	KIF14/MBOAT7/ASPM/NTRK2/WDR62/TACC3/CDK5/BBS2/YWHAE/ASCL1/LRP8/SRGAP2/BAX/NKX2-1/ARHGAP11B/SUN2/FGF13/BCL2A1/MKKS/LRP1/SLC38A2/CRK/HTR6/TMEM14B/PTPRS/LRP6/NEFL/EFHC1/MCPH1/LHX6/PLCB1/PEX13/SYNE2/BAD	34
BP	GO:0000726	non-recombinational repair	28/4749	94/18670	0.1955	0.4945	0.4023	RBBP8/DTX3L/TP53BP1/POLQ/XRCC6/UBE2N/TFIP11/RNF8/SUMO1/BRCC3/UVRAG/POLM/XRCC1/PRPF19/WRAP53/AUNIP/PIAS4/MDC1/NHEJ1/MAD2L2/RAD52/OGG1/ATM/HERC2/RNF138/ERCC1/BARD1/RNF168	28
BP	GO:0070167	regulation of biomineral tissue development	28/4749	94/18670	0.1955	0.4945	0.4023	TWIST1/NOTCH1/ISG15/CCR1/BMP2K/WNT10B/NBR1/FBXO5/CCL3/TGFB3/ATF4/FAM20C/BCOR/S1PR1/ATRAID/TRPM4/AMTN/CYP27B1/ACVR2B/CEBPB/SRGN/BGLAP/FZD9/TXLNG/TMEM119/TGFB1/AMELX/P2RX7	28
BP	GO:0008593	regulation of Notch signaling pathway	31/4749	105/18670	0.1957	0.4947	0.4025	NOTCH1/JAG2/CHAC1/BCL6/TSPAN5/TP63/ASCL1/MAML1/STAT3/ERH/MAML2/ARRB1/RBPJ/ENHO/CBFA2T2/SYNJ2BP/JAG1/PRKCI/NOD2/AAK1/CD46/NFKBIA/SLC35C1/DTX1/NRARP/POGLUT1/GDPD5/EGFL7/ARRDC1/HIF1AN/DLL1	31
BP	GO:0042026	protein refolding	13/4749	40/18670	0.1966	0.4953	0.403	PPIF/HSPA2/PDCL/HSPA5/HSPA1A/PPIH/HSPA9/FKBP1A/HSPA6/NKTR/HSPA1L/HSPA14/DNAJB2	13
BP	GO:0042036	negative regulation of cytokine biosynthetic process	13/4749	40/18670	0.1966	0.4953	0.403	IL10/KLF4/BCL3/ZFP36/FOXP3/PTPRC/SIGIRR/LAG3/GHRL/IL4/TYROBP/ASB1/ZFPM1	13
BP	GO:0072583	clathrin-dependent endocytosis	13/4749	40/18670	0.1966	0.4953	0.403	HIP1/CLTB/UNC119/HIP1R/AP2S1/AAK1/DNAJC6/SYT11/UBQLN2/CANX/DLL1/KIAA1107/SLC9B2	13
BP	GO:0009247	glycolipid biosynthetic process	20/4749	65/18670	0.1968	0.4953	0.403	B3GNT5/GBGT1/FA2H/PIGK/PIGH/DPM2/ST8SIA1/GAL3ST2/PIGQ/PIGO/PIGC/PIGW/B4GALT5/GAL3ST4/PIGM/PIGA/ST8SIA3/ST6GALNAC6/PIGG/PIGT	20
BP	GO:0035308	negative regulation of protein dephosphorylation	20/4749	65/18670	0.1968	0.4953	0.403	PPP1R14A/LGALS3/YWHAE/PPP1R14B/TNF/SWAP70/URI1/BOD1/PHACTR2/TIPRL/FKBP1A/GNAI2/STYXL1/PPP1R16B/MGAT5/PPP1R8/PPP1R26/PPP1R15A/PPP1R9B/PPP1R2	20
BP	GO:0070192	chromosome organization involved in meiotic cell cycle	20/4749	65/18670	0.1968	0.4953	0.403	BUB1B/TRIP13/BUB1/NCAPD2/PPP2R1A/SYCE3/UBE2B/RAD51/DMC1/CCNE2/TERF1/NCAPH/REC8/STAG3/SYCE2/NCAPH2/ANKRD31/ATM/MLH3/RNF212	20
BP	GO:0006370	7-methylguanosine mRNA capping	11/4749	33/18670	0.197	0.4953	0.403	CDK7/POLR2I/ERCC2/GTF2H2/POLR2C/GTF2H1/MNAT1/POLR2J/GTF2H5/NCBP2/POLR2A	11
BP	GO:0014072	response to isoquinoline alkaloid	11/4749	33/18670	0.197	0.4953	0.403	FOSB/MAP1LC3A/PEA15/MTOR/AIF1/CNR1/PPP5C/PRKCE/PPP1R9B/NPFF/ATG7	11
BP	GO:0033028	myeloid cell apoptotic process	11/4749	33/18670	0.197	0.4953	0.403	IRF7/THRA/CCR5/CDKN2A/NOD2/MAEA/IRF3/ADIPOQ/CLEC5A/ARF6/SIRT1	11
BP	GO:0043278	response to morphine	11/4749	33/18670	0.197	0.4953	0.403	FOSB/MAP1LC3A/PEA15/MTOR/AIF1/CNR1/PPP5C/PRKCE/PPP1R9B/NPFF/ATG7	11
BP	GO:0046633	alpha-beta T cell proliferation	11/4749	33/18670	0.197	0.4953	0.403	EBI3/IL18/TNFSF4/LGALS9/CCR2/PTPRC/HLA-E/CD3E/RIPK2/ZAP70/IL23A	11
BP	GO:0048011	neurotrophin TRK receptor signaling pathway	11/4749	33/18670	0.197	0.4953	0.403	NTRK2/NTRK1/CYFIP1/ZFYVE27/CYFIP2/SRC/NTRK3/DDIT4/NDN/NTF3/SLC9A6	11
BP	GO:0070232	regulation of T cell apoptotic process	11/4749	33/18670	0.197	0.4953	0.403	PDCD1/LGALS3/PRELID1/LGALS9/DOCK8/RIPK3/IL7R/IDO1/GIMAP8/TSC22D3/JAK3	11
BP	GO:1990138	neuron projection extension	48/4749	168/18670	0.197	0.4953	0.403	VEGFA/AURKA/SRF/BCL11A/CYFIP1/CDK5/SEMA4C/TNFRSF12A/SEMA7A/CTTN/USP9X/ZFYVE27/SEMA3G/CYFIP2/TIAM1/SYT4/SEMA6C/NTRK3/PLXNA1/PAK1/CPNE5/SEMA6B/SMURF1/ARHGAP4/TWF2/L1CAM/DVL1/ULK1/LRP1/LIMK1/TTL/NDN/SEMA3B/DDR1/SEMA5B/RASAL1/PTPRS/SEMA4D/LLPH/RAPH1/RUFY3/SEMA5A/RTN4R/ADNP/TRPC5/GDI1/ILK/SLC9A6	48
BP	GO:0007034	vacuolar transport	41/4749	142/18670	0.1972	0.4956	0.4032	NDFIP2/GRN/ATP6V0D1/CHMP2B/HSPA1A/UBXN6/SNF8/SORL1/DTX3L/MON1B/VCP/CLU/TMEM50A/M6PR/SMURF1/PINK1/TMEM106B/CACNG3/VPS51/AP3D1/LRP1/HMGXB4/HGS/HOOK2/NCOA4/MGRN1/VPS52/AP4M1/SNAPIN/LAMP1/VTI1B/CHMP1A/DENND3/CHMP2A/PIK3R4/VPS13D/VPS39/EHD3/CCDC91/CHMP3/RAB12	41
BP	GO:0061448	connective tissue development	76/4749	273/18670	0.1973	0.4956	0.4032	EGR1/NOTCH1/SULF2/COL5A1/SRF/EVC/ANXA2P2/BBS2/COL6A2/THRA/TYMS/CREB3L2/CSF1/CRIP1/ARRDC3/ITGB8/ANXA2/ESRRA/WNT10B/HYAL3/MSX1/BARX2/SORL1/SNAI1/ALX1/CFLAR/CSGALNACT1/GNAS/UBB/ARID5B/PTHLH/FGF9/SLC25A25/POC1A/COL6A1/RUNX2/RORC/CASR/CARM1/COL11A1/TRPM4/CHRDL2/MEF2D/OXCT1/MKKS/TRPS1/WNT7A/SOX8/TGFBI/GDF7/SH3PXD2B/SNX19/TIMP1/CD44/MAF/LRP5L/SMAD1/GHRL/EIF2AK3/IFT80/CD34/POR/DGAT2/LRP6/HOXA11/BMP10/BMP3/AXIN2/ACTA2/PPARD/CER1/TGFB1/RARA/PDGFB/AMELX/SIRT1	76
BP	GO:0043434	response to peptide hormone	119/4749	436/18670	0.1983	0.4979	0.4051	EGR1/NR4A1/EGR2/IL1B/RAB31/NR4A3/PPARG/ICAM1/SH2B2/IL10/CCNA2/CYFIP1/ATP6V0D1/TIMP4/MZB1/CEACAM1/CDC6/SOCS2/EIF4EBP1/SYAP1/SLC2A8/CYBB/PTPN1/ATP6V0B/MTOR/ESRRA/STAT3/ADCY4/SORL1/MYO5A/SRC/SOCS3/PKM/GGH/CFLAR/CAMK2A/RAB13/SRSF4/ATP6V1E1/IGF1R/CRY1/PAK1/ENHO/ADCY6/PHEX/FFAR3/SLC2A4/EIF2B3/MBD5/ATP6V0C/FOXO1/RNF40/PHIP/UPRT/ANXA5/PRKCI/ATP6V1A/TLR2/SP1/ADIPOR1/SLA2/ARG1/GNAI2/INSRR/STAT4/EPM2AIP1/ACVR1C/TIMP1/TSHR/CA2/CRK/ADCY3/CYBA/APRT/TFF1/BSG/GSK3A/RARRES2/ATP6V1G1/BGLAP/ADM/GHRL/CDC5L/ADIPOQ/GPR21/POR/TNFSF10/FER/AANAT/STAT5A/ZFP36L1/GCLC/CPEB1/LRP6/PRKCB/PRKACB/INSR/MAX/ADCY9/APC/HDAC9/STAT1/ATP6V1E2/NEFL/CYP11A1/NUCKS1/TGFB1/JAK3/TRIM16/SESN2/SHC1/GKAP1/LPIN1/FYN/NME2/TRIB3/MGARP/USO1/SIRT1	119
BP	GO:0051208	sequestering of calcium ion	38/4749	131/18670	0.1988	0.499	0.4059	PTPN6/CHERP/JSRP1/NOL3/BAX/CXCL10/TRPC1/SLC25A23/MYO5A/PDE4D/HTR2A/CCL3/SRI/PKD2/CCR5/HTT/GSTO1/TPCN1/PTPRC/CORO1A/RASA3/ANXA5/CXCL9/DRD1/FKBP1A/DDIT3/THY1/CD19/NTSR1/PRKCE/CYBA/LACRT/IL13/CAMK2D/F2R/PLCB1/TGFB1/P2RX7	38
BP	GO:0019827	stem cell population maintenance	45/4749	157/18670	0.1992	0.4998	0.4066	LIF/NOTCH1/ASPM/KLF4/SPI1/TP63/SMC3/SKI/STAT3/PELO/SETD6/RBPJ/PRDM16/FOXO1/ZFP36L2/JAG1/DIS3L2/SALL4/CNOT3/FANCC/SS18/GNL3/WNT7A/ZHX2/POLR2I/ARID1A/VPS72/MMP24/POLR2C/YAP1/KLF10/ELAVL1/SFRP1/POLR2J/SMC1A/MED12/PBX1/LBH/MCPH1/DLL1/KDM4C/MED28/CUL4A/POLR2A/LDB1	45
BP	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	26/4749	87/18670	0.2011	0.4998	0.4066	IL18/NTRK2/NTRK1/PDGFA/PTPN6/PLXNB1/TNF/SRC/NTRK3/IGF1R/PIK3R5/FLT3/OSM/FLT1/UBE3A/FLT4/F2R/SEMA4D/INSR/NCF1/NTF3/PPARD/HCST/PDGFB/FYN/SIRT1	26
BP	GO:0035904	aorta development	18/4749	58/18670	0.2012	0.4998	0.4066	NOTCH1/SRF/PRDM1/MYH10/ADAMTS6/RBPJ/PKD2/SMAD6/DCTN5/JAG1/PLXND1/LRP1/TFAP2B/TAB1/LOXL1/ADAMTS9/NPRL3/FGF8	18
BP	GO:0006086	acetyl-CoA biosynthetic process from pyruvate	6/4749	16/18670	0.2013	0.4998	0.4066	PDPR/PDHB/PDHX/DLAT/MPC1/GSTZ1	6
BP	GO:0006103	2-oxoglutarate metabolic process	6/4749	16/18670	0.2013	0.4998	0.4066	MRPS36/OGDH/DLST/GPT2/D2HGDH/ADHFE1	6
BP	GO:0009130	pyrimidine nucleoside monophosphate biosynthetic process	6/4749	16/18670	0.2013	0.4998	0.4066	TYMS/DHODH/UPRT/DCTD/CMPK1/UCK2	6
BP	GO:0010885	regulation of cholesterol storage	6/4749	16/18670	0.2013	0.4998	0.4066	PPARG/ABCG1/ABCA1/TTC39B/PPARD/SREBF2	6
BP	GO:0019372	lipoxygenase pathway	6/4749	16/18670	0.2013	0.4998	0.4066	ALOX5AP/GPX1/PON2/ALOX5/GPX4/HPGD	6
BP	GO:0030214	hyaluronan catabolic process	6/4749	16/18670	0.2013	0.4998	0.4066	HYAL3/CHP1/CD44/HEXB/GUSB/TGFB1	6
BP	GO:0030575	nuclear body organization	6/4749	16/18670	0.2013	0.4998	0.4066	DYRK3/PML/SERBP1/SUMO1/WRAP53/SUMO1P1	6
BP	GO:0030952	establishment or maintenance of cytoskeleton polarity	6/4749	16/18670	0.2013	0.4998	0.4066	KIF2C/LMNA/MAPKAP1/ARHGAP35/RHOF/CKAP5	6
BP	GO:0031269	pseudopodium assembly	6/4749	16/18670	0.2013	0.4998	0.4066	CDC42EP4/SRGAP2/CDC42EP1/APC/C15orf62/CDC42	6
BP	GO:0031958	corticosteroid receptor signaling pathway	6/4749	16/18670	0.2013	0.4998	0.4066	YWHAH/NR3C1/CRY1/ARID1A/PPP5C/ARNTL	6
BP	GO:0032604	granulocyte macrophage colony-stimulating factor production	6/4749	16/18670	0.2013	0.4998	0.4066	IL1B/IL18/CD80/LILRA2/PAEP/IL23A	6
BP	GO:0034116	positive regulation of heterotypic cell-cell adhesion	6/4749	16/18670	0.2013	0.4998	0.4066	IL1B/IL10/TNF/FLOT1/THY1/CD44	6
BP	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation	6/4749	16/18670	0.2013	0.4998	0.4066	CYFIP1/CORO1B/HIP1R/PICK1/AP1AR/WAS	6
BP	GO:0043174	nucleoside salvage	6/4749	16/18670	0.2013	0.4998	0.4066	TYMP/TK1/HPRT1/MTAP/APRT/UCK2	6
BP	GO:0043217	myelin maintenance	6/4749	16/18670	0.2013	0.4998	0.4066	ABCD1/FA2H/ABCD2/CLU/MPP5/NDRG1	6
BP	GO:0044827	modulation by host of viral genome replication	6/4749	16/18670	0.2013	0.4998	0.4066	TBC1D20/FMR1/CCNK/ZC3H12A/STOM/NUCKS1	6
BP	GO:0045116	protein neddylation	6/4749	16/18670	0.2013	0.4998	0.4066	RPL5/DCUN1D4/RNF7/NAE1/RPL11/UBE2F	6
BP	GO:0048385	regulation of retinoic acid receptor signaling pathway	6/4749	16/18670	0.2013	0.4998	0.4066	CYP26C1/EZH2/ASXL1/NR2C1/TRIM16/DHRS3	6
BP	GO:0048820	hair follicle maturation	6/4749	16/18670	0.2013	0.4998	0.4066	WNT10B/MYO5A/RBPJ/ERCC2/NOM1/NSUN2	6
BP	GO:0050774	negative regulation of dendrite morphogenesis	6/4749	16/18670	0.2013	0.4998	0.4066	YWHAH/GORASP1/UBE3A/RAPGEF2/ID1/TRPC5	6
BP	GO:0070293	renal absorption	6/4749	16/18670	0.2013	0.4998	0.4066	GSN/KLHL3/ADIPOQ/HBB/HAS2/CLDN4	6
BP	GO:0071871	response to epinephrine	6/4749	16/18670	0.2013	0.4998	0.4066	PDE4D/PDE4B/ATP2B4/SIRT2/ADIPOQ/RNLS	6
BP	GO:0072109	glomerular mesangium development	6/4749	16/18670	0.2013	0.4998	0.4066	EGR1/NOTCH1/CFLAR/CD34/ACTA2/PDGFB	6
BP	GO:2000369	regulation of clathrin-dependent endocytosis	6/4749	16/18670	0.2013	0.4998	0.4066	UNC119/HIP1R/AAK1/DNAJC6/SYT11/UBQLN2	6
BP	GO:1904892	regulation of STAT cascade	42/4749	146/18670	0.2013	0.4998	0.4066	LIF/NOTCH1/IL18/CSF2/IL21/CSF1R/IL10/DOT1L/BCL3/TNFRSF18/CNTF/CDK5/NF2/PPP2R1A/SOCS2/TNF/STAT3/PARP14/SOCS3/FLT3/PTK6/PTPRC/PPP2CA/ADIPOR1/IL26/OSM/HGS/GGNBP2/PIBF1/IL7R/MGAT5/CNOT7/IL13/IL20/IL4/ARL2BP/F2R/CRLF3/IL10RA/JAK3/FYN/IL23A	42
BP	GO:0008406	gonad development	61/4749	217/18670	0.2018	0.5008	0.4074	VEGFA/ASPM/ICAM1/NTRK1/FANCG/KIF18A/HSPA5/BRCA2/BAX/NASP/PLEKHA1/HYAL3/SRC/NUDT1/NKX2-1/ARRB1/RRM1/DMC1/RAB13/UBB/ARID5B/FGF9/BIK/SDC1/PATZ1/TBC1D20/MKKS/FNDC3A/SOX8/BASP1/UBE3A/NCOA4/REC8/WDR19/CITED2/CEBPB/IRX5/BCL2L1/ADAM15/ZNF830/CTNNA1/RBMY1B/SFRP1/ESR1/KDM5A/TNFSF10/HOXA11/INSR/NUPR1/FGF8/ARID4A/ADAMTS1/ATM/WDR48/TMF1/RARA/CCND1/RDH10/GATA3/ERCC1/SIRT1	61
BP	GO:0051961	negative regulation of nervous system development	87/4749	315/18670	0.2019	0.5008	0.4074	CRMP1/IL1B/NOTCH1/ASPM/TP73/DUSP10/BCL11A/CNTF/YWHAH/CDK5/SPP1/GORASP1/GPR161/SEMA4C/ASCL1/TNF/SEMA7A/SRGAP2/PLK2/CEND1/SKI/TNFRSF21/RGMA/LDLR/STAT3/SEMA3G/TSPO/SORL1/ARHGEF2/SYT4/SEMA6C/NTRK3/ADCY6/MYLIP/SEMA6B/PTPN9/LGALS1/CBFA2T2/JAG1/STX1B/LRP4/CARM1/FGF13/TBX6/ARHGAP4/IFT122/TLR2/LRP1/THY1/WNT7A/SOX8/ZHX2/UBE3A/CTSZ/HMG20A/DTX1/SOX11/SEMA3B/VIM/SEMA5B/PMP22/CTNNA1/GSK3A/RAPGEF2/SNAPIN/SIRT2/EIF2AK3/RAP1GAP2/PTPRS/ITM2C/DICER1/PRKACB/SEMA4D/ARF6/ARHGDIA/MBD1/PBX1/DLL1/NKX6-2/ID1/RUFY3/TGFB1/SEMA5A/RTN4R/TRPC5/GDI1/TLX3	87
BP	GO:0050921	positive regulation of chemotaxis	39/4749	135/18670	0.2032	0.5039	0.4099	CXCL13/VEGFA/ITGA2/WNK1/RAC1/TIRAP/CCR1/DAPK2/LGALS9/HMGB1/CSF1/CXCL10/SERPINE1/SWAP70/CCR6/CCR2/CCR4/TIAM1/CCL3/NTRK3/CD74/S1PR1/CASR/AIF1/FPR2/C3AR1/RAC2/RARRES2/F3/C1QBP/CCL7/NTF3/THBS4/TGFB1/SEMA5A/PDGFB/CCL27/VEGFC/IL23A	39
BP	GO:0051209	release of sequestered calcium ion into cytosol	36/4749	124/18670	0.2048	0.5078	0.4131	PTPN6/CHERP/JSRP1/NOL3/BAX/CXCL10/TRPC1/MYO5A/PDE4D/HTR2A/CCL3/SRI/PKD2/CCR5/HTT/GSTO1/TPCN1/PTPRC/CORO1A/RASA3/CXCL9/DRD1/FKBP1A/DDIT3/THY1/CD19/NTSR1/PRKCE/CYBA/LACRT/IL13/CAMK2D/F2R/PLCB1/TGFB1/P2RX7	36
BP	GO:0008088	axo-dendritic transport	21/4749	69/18670	0.2049	0.5078	0.4131	KIF4A/KIF1C/SFPQ/BLOC1S6/BLOC1S1/CNIH2/KLC3/BLOC1S4/AP3D1/DTNBP1/FMR1/AP3M2/SNAPIN/MAP1A/NEFL/AP3B2/UCHL1/SPG7/SYBU/MGARP/TERF2	21
BP	GO:0051452	intracellular pH reduction	16/4749	51/18670	0.2053	0.5087	0.4138	GRN/ATP6V0D1/ATP6V0B/ATP6V1E1/PPT1/ATP6V0C/ATP6V1A/ROGDI/CA2/RAB38/SNAPIN/ATP6V1G1/DMXL1/ATP6V1E2/DMXL2/CCDC115	16
BP	GO:0048640	negative regulation of developmental growth	33/4749	113/18670	0.2061	0.5105	0.4153	MAPK11/PLAC8/TP73/CDKN1A/DUSP10/BCL11A/CDK5/BBS2/SPP1/PTCH1/SOCS2/SEMA4C/SEMA7A/SEMA3G/FXN/NKD1/SEMA6C/PAK1/SEMA6B/FGF13/STK3/ARHGAP4/WWC2/SEMA3B/SEMA5B/GSK3A/SFRP1/PTPRS/SEMA4D/SEMA5A/RTN4R/MIR17HG/KCNK2	33
BP	GO:0071695	anatomical structure maturation	47/4749	165/18670	0.2066	0.5114	0.4161	CDKN1A/KLF2/AURKA/BCL11A/TRIP13/C1QL1/PPP2R1A/TYMS/PLXNB1/CEND1/BRCA2/MTOR/DCHS1/WNT10B/CCNB1/MYO5A/FBXO5/PABPC1L/DMC1/RBPJ/LYL1/FAM20C/S1PR1/PICK1/TBX6/SCARF1/FEM1B/DDIT3/MAEA/ERCC2/REC8/RECK/IRX5/B4GALT5/SIRT2/NOM1/C1QA/SEMA4D/MBTPS2/XYLT1/ANKRD17/NSUN2/CDC25B/CDH5/GATA3/CX3CR1/RAC3	47
BP	GO:0022617	extracellular matrix disassembly	24/4749	80/18670	0.2067	0.5115	0.4161	FURIN/FSCN1/TIMP2/MMP9/TMPRSS6/CAPN1/MMP12/CST3/CLASP2/A2M/FLOT1/LRP1/SH3PXD2B/TIMP1/CD44/ADAM15/DDR1/KLKB1/SCUBE1/BSG/CTRB1/KLK5/HTRA1/TGFB1	24
BP	GO:0006900	vesicle budding from membrane	30/4749	102/18670	0.207	0.5121	0.4166	SEC13/ANXA2P2/GORASP1/SEC24D/MCFD2/ANXA2/F5/STX5/SEC16A/CNIH2/SLC2A4/ANKRD28/TBC1D20/PRKCI/AP3D1/S100A10/INSIG1/TMED9/GBF1/TMED10/CTSZ/DNM1/TRAPPC4/RAB1A/PPP6C/PEF1/P2RX7/PPP6R1/RAB1B/USO1	30
BP	GO:0030510	regulation of BMP signaling pathway	27/4749	91/18670	0.2073	0.5126	0.417	SKIL/NOTCH1/ITGA3/SKI/TMPRSS6/MSX1/DAND5/SMAD7/SORL1/NUMA1/GREM2/PELO/SFRP4/RBPJ/SMAD6/SMURF1/LEMD3/TFAP2B/FKBP8/RBPMS2/SOX11/SFRP1/FBXL15/CER1/HTRA1/CDH5/ILK	27
BP	GO:2000404	regulation of T cell migration	14/4749	44/18670	0.2089	0.5156	0.4194	CXCL13/WNK1/CCL20/CD200/CXCL10/DOCK8/CCR6/RIPK3/CCR2/AIF1/IL27RA/CRK/CD99L2/CCL27	14
BP	GO:0034763	negative regulation of transmembrane transport	37/4749	128/18670	0.2094	0.5156	0.4194	TWIST1/PPIF/IL1B/GEM/SESTD1/MMP9/YWHAE/TNF/SIRT6/PEA15/MTOR/REM1/FABP5/KCNE3/SRI/PKD2/RSC1A1/GPR35/GSTO1/OAZ3/REM2/SUMO1/YWHAQ/NTSR1/FMR1/OAZ2/PRKCE/GSK3A/CAMK2D/KCNH2/KCNE4/ISCU/GOPC/PRKCB/OAZ1/TGFB1/CRBN	37
BP	GO:0060485	mesenchyme development	77/4749	278/18670	0.2099	0.5156	0.4194	TWIST1/IL1B/NOTCH1/FAM83D/TGFB1I1/CORO1C/SEMA4C/SEMA7A/MTOR/DCHS1/MSX1/DAND5/SMAD7/SEMA3G/PDCD4/SNAI1/NKX2-1/ACTG2/ALX1/TIAM1/SEMA6C/TRIM62/SDCBP/TGFB3/PTK7/WWTR1/FGF9/RBPJ/PKD2/SEMA6B/EFNB1/CYP26C1/JAG1/FAM172A/CLASP2/CFL1/EZH2/PPP2CA/ADIPOR1/NOLC1/VASN/MDM4/SOX8/LDLRAD4/BASP1/DDX17/EPB41L5/CITED2/SOX11/SEMA3B/YAP1/ADAM15/ZNF703/POGLUT1/SEMA5B/DLG5/PHLDB1/SFRP1/GLIPR2/PAX1/ZFP36L1/MAD2L2/LRP6/SEMA4D/FGF8/STAT1/AXIN2/ACTA2/CER1/TGFB1/SEMA5A/HAS2/MAPK1/RDH10/PEF1/LAMA5/AMELX	77
BP	GO:0070265	necrotic cell death	19/4749	62/18670	0.2101	0.5156	0.4194	PPIF/TNF/TLR4/NOL3/BAX/TSPO/RIPK3/ARHGEF2/CFLAR/FAS/MAP3K5/CYLD/IRF3/BIRC3/TRAF2/FZD9/SLC25A4/SPATA2/PGAM5	19
BP	GO:1904356	regulation of telomere maintenance via telomere lengthening	19/4749	62/18670	0.2101	0.5156	0.4194	AURKB/NEK2/SMG5/SRC/PIF1/CCT5/TERF1/TNKS2/ACD/CTC1/POT1/SMG6/ATR/TINF2/ATM/MAPK1/FBXO4/TERF2/CCT3	19
BP	GO:0006359	regulation of transcription by RNA polymerase III	8/4749	23/18670	0.2104	0.5156	0.4194	MTOR/TENM1/NAB2/PRDX5/BRF2/ELL/ZNF345/MAF1	8
BP	GO:0006541	glutamine metabolic process	8/4749	23/18670	0.2104	0.5156	0.4194	PFAS/GLS2/ASNS/GLUD1/CTPS2/ALDH5A1/NIT2/ASNSD1	8
BP	GO:0007064	mitotic sister chromatid cohesion	8/4749	23/18670	0.2104	0.5156	0.4194	CDCA5/CDC20/BOD1/DSCC1/CHTF8/SMC1A/POGZ/SMC5	8
BP	GO:0009310	amine catabolic process	8/4749	23/18670	0.2104	0.5156	0.4194	SMOX/SARDH/SAT1/BHMT/ATP2B4/IDO1/ALDH7A1/SLC44A1	8
BP	GO:0010528	regulation of transposition	8/4749	23/18670	0.2104	0.5156	0.4194	APOBEC3H/APOBEC3B/TDRD9/AICDA/ZNF93/ZNF91/UBR2/PIWIL4	8
BP	GO:0010529	negative regulation of transposition	8/4749	23/18670	0.2104	0.5156	0.4194	APOBEC3H/APOBEC3B/TDRD9/AICDA/ZNF93/ZNF91/UBR2/PIWIL4	8
BP	GO:0016578	histone deubiquitination	8/4749	23/18670	0.2104	0.5156	0.4194	USP36/ENY2/BAP1/KAT2A/SUPT3H/ASXL1/TAF10/BRCC3	8
BP	GO:0032098	regulation of appetite	8/4749	23/18670	0.2104	0.5156	0.4194	BBS2/NENF/SLC22A3/CCK/MKKS/NUCB2/GHRL/NPFF	8
BP	GO:0032717	negative regulation of interleukin-8 production	8/4749	23/18670	0.2104	0.5156	0.4194	IL10/KLF4/BCL3/ARRB1/CD33/OTUD7B/TLR6/ANXA4	8
BP	GO:0034695	response to prostaglandin E	8/4749	23/18670	0.2104	0.5156	0.4194	PPARG/TNFSF4/PTGER4/ADCY6/PRKCE/PTGER2/SFRP1/AANAT	8
BP	GO:0051904	pigment granule transport	8/4749	23/18670	0.2104	0.5156	0.4194	MYO7A/BBS2/MYO5A/BLOC1S6/MKKS/RAB27A/ASIP/RAB1A	8
BP	GO:0060055	angiogenesis involved in wound healing	8/4749	23/18670	0.2104	0.5156	0.4194	MCAM/SRF/HPSE/SERPINE1/GPX1/ADIPOR2/PRCP/CD34	8
BP	GO:0060445	branching involved in salivary gland morphogenesis	8/4749	23/18670	0.2104	0.5156	0.4194	PDGFA/TNF/TGM2/PLXNA1/PLXND1/FGF8/LAMA5/ESRP2	8
BP	GO:0060479	lung cell differentiation	8/4749	23/18670	0.2104	0.5156	0.4194	KLF2/THRA/ASCL1/NKX2-1/SPDEF/RBPJ/YAP1/IL13	8
BP	GO:0072243	metanephric nephron epithelium development	8/4749	23/18670	0.2104	0.5156	0.4194	LIF/WWTR1/PKD2/SOX8/YAP1/ADIPOQ/UMOD/STAT1	8
BP	GO:0086012	membrane depolarization during cardiac muscle cell action potential	8/4749	23/18670	0.2104	0.5156	0.4194	RANGRF/SCN1B/HCN2/KCNJ2/TRPM4/CACNB2/SLMAP/GJA5	8
BP	GO:0099500	vesicle fusion to plasma membrane	8/4749	23/18670	0.2104	0.5156	0.4194	STX11/SNAP47/SNAP29/STX1B/STX19/SNAP23/SNAPIN/STX2	8
BP	GO:2000050	regulation of non-canonical Wnt signaling pathway	8/4749	23/18670	0.2104	0.5156	0.4194	NKD1/TIAM1/SFRP4/RNF213/SFRP1/IFT80/RSPO3/MLLT3	8
BP	GO:0043401	steroid hormone mediated signaling pathway	52/4749	184/18670	0.2107	0.5162	0.42	VDR/NR4A1/NR4A3/PPARG/NR3C2/KANK2/PMEPA1/CBFB/YWHAH/DNAJA1/CYP7B1/TGFB1I1/TP63/THRA/ESRRA/NR3C1/PAQR7/SRC/PPARGC1B/TRIP4/CRY1/PAK1/RORC/CARM1/CDK7/SMARCA4/PIAS1/RXRA/CREBRF/ARID1A/PARK7/PPP5C/UBE3A/NCOA4/DDX17/DDX54/PIAS2/ARNTL/YAP1/PADI2/SFRP1/TAF7/ESR1/DEFA1B/AKAP13/LBH/PPARD/STRN3/NR2C1/RARA/NCOR1/SIRT1	52
BP	GO:0050851	antigen receptor-mediated signaling pathway	87/4749	316/18670	0.2115	0.5172	0.4208	CD276/WNK1/SH2B2/PTPN6/CBFB/LGALS3/CEACAM1/BLK/HLA-DQB2/BAX/BTN2A2/SPPL3/TNFRSF21/FOXP3/ERMAP/PLEKHA1/CTLA4/GCSAM/PSMD8/LILRB4/PDE4D/BTK/PDE4B/PSMD1/PSMD2/PAK1/GRAP2/UBE2N/RPS3/PSMF1/EIF2B3/PAK3/HLA-DPA1/CD79B/PTPRC/EZR/CYLD/NFAM1/RFTN1/DUSP22/LAT/HLA-DRA/KCNN4/PSMD9/TXK/SLA2/PSMA5/PLCL2/THY1/CD19/MNDA/PSMB7/FBXW11/PSMD5/ZC3H12A/ITK/CD3E/HLA-DQA2/PSME2/BTRC/CARD11/PSMB5/BTN3A2/PRNP/RIPK2/PRKCB/PSMB4/HLA-DPB1/TRAF6/PSMA3/GCSAML/THEMIS/PSMD10/SLC39A10/PSMB1/WAS/PSMD7/PSMB3/HHLA2/MAPK1/HLA-DRB1/ZAP70/PSMC5/GATA3/FYN/PAK2/PSMD11	87
BP	GO:0002714	positive regulation of B cell mediated immunity	12/4749	37/18670	0.2116	0.5172	0.4208	TNFSF4/TFRC/TNF/TP53BP1/BTK/PTPRC/HLA-E/LTA/TNFSF13/IL4/MAD2L2/TGFB1	12
BP	GO:0002891	positive regulation of immunoglobulin mediated immune response	12/4749	37/18670	0.2116	0.5172	0.4208	TNFSF4/TFRC/TNF/TP53BP1/BTK/PTPRC/HLA-E/LTA/TNFSF13/IL4/MAD2L2/TGFB1	12
BP	GO:0006623	protein targeting to vacuole	12/4749	37/18670	0.2116	0.5172	0.4208	SORL1/MON1B/CLU/M6PR/SMURF1/AP3D1/HGS/NCOA4/AP4M1/VTI1B/PIK3R4/VPS13D	12
BP	GO:0060323	head morphogenesis	12/4749	37/18670	0.2116	0.5172	0.4208	CSRNP1/SKI/ASPH/PLEKHA1/MSX1/TGFB3/ARID5B/SSBP3/DLX5/LRP6/TGFB1/ANKRD11	12
BP	GO:2000249	regulation of actin cytoskeleton reorganization	12/4749	37/18670	0.2116	0.5172	0.4208	CSF1R/FES/HCK/CDK5/NTRK3/CD2AP/ARHGDIA/NTF3/TGFB1/BCAS3/CDC42/CCL27	12
BP	GO:0006801	superoxide metabolic process	22/4749	73/18670	0.2126	0.5185	0.4218	ACP5/NCF4/CLEC7A/TNF/NOXA1/CYBB/CD177/NQO1/DHFR/PREX1/FANCC/GNAI2/FPR2/PARK7/SH3PXD2B/MPO/CYBA/TYROBP/CCS/NCF1/TGFB1/PRDX1	22
BP	GO:0000038	very long-chain fatty acid metabolic process	10/4749	30/18670	0.2126	0.5185	0.4218	TECR/ABCD1/ABCD2/SLC27A2/TECRL/ELOVL7/PEX2/ELOVL1/CYP4F12/SLC27A4	10
BP	GO:0000305	response to oxygen radical	10/4749	30/18670	0.2126	0.5185	0.4218	TNF/NQO1/DHFR/FANCC/PARK7/MPO/CCS/ADPRHL2/TXNRD2/PRDX1	10
BP	GO:0048384	retinoic acid receptor signaling pathway	10/4749	30/18670	0.2126	0.5185	0.4218	PML/CYP26C1/EZH2/ACTN4/ASXL1/RXRA/NR2C1/RARA/TRIM16/DHRS3	10
BP	GO:0070979	protein K11-linked ubiquitination	10/4749	30/18670	0.2126	0.5185	0.4218	UBE2C/UBE2A/UBE2S/UBE2B/UBE2H/ANAPC11/ANAPC1/ANAPC13/CDC16/UBE2W	10
BP	GO:1904292	regulation of ERAD pathway	10/4749	30/18670	0.2126	0.5185	0.4218	USP19/HERPUD1/UBXN1/SGTA/UBE2G2/BCAP31/EDEM2/BRSK2/UBQLN2/UBAC2	10
BP	GO:0006816	calcium ion transport	118/4749	434/18670	0.2131	0.5187	0.422	VDR/GEM/ICAM1/ADORA2A/HSPA2/PTPN6/CCR1/SESTD1/ORAI2/CDK5/ANXA2P2/LGALS3/YWHAE/CHERP/PML/TSPAN13/CDH23/JSRP1/CHRNA10/NCS1/NOL3/BAX/CXCL10/TRPC1/LILRA2/SLC25A23/ANXA2/HOMER2/TSPO/MYO5A/HCRT/REM1/P2RX1/HOMER1/PDE4D/HTR2A/ATP2A1/CCL3/CAMK2A/KCNE3/PDE4B/SRI/MICU1/CD33/CYSLTR1/SLC3A2/PKD2/SLC25A25/CCR5/HTT/CCL2/PARL/GPR35/ATP1B1/CASR/GSTO1/TPCN1/PTPRC/REM2/CORO1A/TRPM4/RASA3/ANXA5/CACNG3/STAC3/ORAI3/CXCL9/KCNN4/BAK1/DRD1/LILRB2/FKBP1A/ATP2B4/STAC/DDIT3/THY1/CD19/CACNA2D2/SUMO1/GNAI2/NTSR1/SLC24A3/VDAC1/CYP27B1/FMR1/CAMK2G/PRKCE/CUL5/GRIN3B/CYBA/LILRA5/LACRT/IL13/CAMK2D/P2RX5/PRNP/F2R/CSN2/EPB41/PRKCB/TRPC7/AHNAK/SPHK2/CACNB2/TMC2/CATSPER2/EHD3/CLCA1/FFAR1/PLCB1/TGFB1/NMUR1/TRPC5/SPG7/PDGFB/P2RX7/SLC35G1/FYN	118
BP	GO:0014910	regulation of smooth muscle cell migration	25/4749	84/18670	0.2134	0.5187	0.422	NR4A3/ITGA2/TRIB1/PDGFA/PLAU/SERPINE1/SORL1/SRC/CORO1B/PLXNA1/PAK1/FGF9/IGFBP3/DOCK5/AIF1/VTN/LRP1/CRK/ADIPOQ/TPM1/ADAMTS1/PPARD/HAS2/PDGFB/ILK	25
BP	GO:0042177	negative regulation of protein catabolic process	38/4749	132/18670	0.2139	0.5187	0.422	PBK/FURIN/IL10/TIMP4/CTSA/TIMP2/ANXA2P2/PML/ANXA2/RYBP/RPL5/SDCBP/ATP13A2/CST3/USP19/PSMF1/N4BP1/UBXN1/IRAK3/PDCL3/SGTA/RPL23/UBE2G2/ATRAID/MDM4/PARK7/TIMP1/AGAP2/SCO1/SNX12/UCHL5/SIRT2/MAD2L2/TIMP3/MAP1A/RPL11/UBAC2/FYN	38
BP	GO:0006383	transcription by RNA polymerase III	17/4749	55/18670	0.2153	0.5187	0.422	GTF3C4/MTOR/TENM1/NAB2/SNAPC5/PRDX5/BRF2/POLR3H/GTF3C2/GTF3C6/BDP1/ELL/CRCP/POLR3GL/ZNF345/MAF1/SNAPC3	17
BP	GO:0042304	regulation of fatty acid biosynthetic process	17/4749	55/18670	0.2153	0.5187	0.422	IL1B/CEACAM1/ABCD1/ABCD2/FABP5/CD74/PRKAB2/ADIPOR2/SLC45A3/INSIG1/ADIPOR1/PRKAG2/PIBF1/ADIPOQ/CYP7A1/TRIB3/SIRT1	17
BP	GO:0043030	regulation of macrophage activation	17/4749	55/18670	0.2153	0.5187	0.422	IL10/TTBK1/GRN/CD200/TLR4/LDLR/IL4R/CCL3/HAVCR2/CD74/PTPRC/SHPK/TLR6/ZC3H12A/IL13/ATM/PJA2	17
BP	GO:0043113	receptor clustering	17/4749	55/18670	0.2153	0.5187	0.422	CDK5/GSN/ETV5/SYNJ2BP/DNAJA3/LRP4/PICK1/PIGR/IFT122/DVL1/SCRIB/THY1/WDR19/FZD9/TGFB1/DLG4/SHISA7	17
BP	GO:0046456	icosanoid biosynthetic process	17/4749	55/18670	0.2153	0.5187	0.422	IL1B/PTGIS/ALOX5AP/GGT1/FABP5/CD74/ALOX5/GGTLC2/TBXAS1/PIBF1/PTGES2/MGST2/GGT7/MGST3/HPGD/PLA2G5/SIRT1	17
BP	GO:0061098	positive regulation of protein tyrosine kinase activity	17/4749	55/18670	0.2153	0.5187	0.422	NTRK2/NEDD9/CSF1R/LRP8/PTPN1/FCGR1A/SRC/UNC119/DOCK3/LILRA5/GHRL/PRNP/NCF1/PDGFB/FYN/DLG4/PAK2	17
BP	GO:0098900	regulation of action potential	17/4749	55/18670	0.2153	0.5187	0.422	DSC2/RANGRF/RNF207/KCNE3/KCNJ2/GPR35/FGF13/TRPM4/GBA/SUMO1/CNR1/NTSR1/FMR1/NPS/CAMK2D/SLMAP/GJA5	17
BP	GO:0001667	ameboidal-type cell migration	125/4749	461/18670	0.2156	0.5187	0.422	CXCL13/EGR3/NR4A1/TWIST1/HBEGF/ANLN/VEGFA/NOTCH1/SDC4/PPARG/ITGA2/DUSP10/ITGA3/KANK2/SRF/KLF4/CTSH/GRN/RFFL/CEACAM1/CORO1C/MMP9/PML/SEMA4C/GPI/HMGB1/PDXDC1/SEMA7A/SRGAP2/PLK2/AKT3/MTOR/ADTRP/GPX1/BAG4/VASH1/SEMA3G/CCR6/SRC/EPHB4/HMOX1/MAPRE2/ALX1/MAP2K3/SEMA6C/CORO1B/RIC8A/DOCK1/RAB13/PAK1/ARID5B/PFN2/AMOT/SEMA6B/EFNB1/DOCK5/PRKX/C5orf30/STARD13/PAK3/SYNJ2BP/PRKCA/CLASP2/WDPCP/ARHGAP4/ATOH8/CFL1/PLXND1/PRCP/SP1/IQSEC1/ADIPOR1/WNT7A/SOX8/JUN/EPB41L5/ACVR1C/LGALS8/TIMP1/TNFSF12/PRKCE/PTPRM/SEMA3B/MAP3K3/ZC3H12A/TBXA2R/FLT4/SEMA5B/ADAMTS9/EMC10/INSL3/IL4/GLIPR2/KRIT1/MYH9/FER/STAT5A/CAPN7/CENPV/SEMA4D/C1QBP/BMP10/ARF6/FGF8/HDAC9/WASF2/PPARD/TMEM201/CER1/PIP5K1A/ID1/TGFB1/BCAS3/SEMA5A/LTB4R2/HAS2/ADAM9/LAMA5/PDGFB/GATA3/VEGFC/PTP4A3/ILK/PRSS3P2/SIRT1	125
BP	GO:0001765	membrane raft assembly	5/4749	13/18670	0.2171	0.5187	0.422	ANXA2P2/ANXA2/RFTN1/FLOT1/S100A10	5
BP	GO:0001845	phagolysosome assembly	5/4749	13/18670	0.2171	0.5187	0.422	MYO7A/CORO1A/TMEM175/RAB34/P2RX7	5
BP	GO:0001973	adenosine receptor signaling pathway	5/4749	13/18670	0.2171	0.5187	0.422	ACPP/ADORA2A/P2RY11/GNAI2/P2RY1	5
BP	GO:0002093	auditory receptor cell morphogenesis	5/4749	13/18670	0.2171	0.5187	0.422	MYO7A/WDPCP/TRIOBP/SCRIB/STRC	5
BP	GO:0002679	respiratory burst involved in defense response	5/4749	13/18670	0.2171	0.5187	0.422	DUSP10/HCK/GRN/RPS19/MPO	5
BP	GO:0002829	negative regulation of type 2 immune response	5/4749	13/18670	0.2171	0.5187	0.422	BCL6/CCR2/HLX/IL27RA/ARG1	5
BP	GO:0003157	endocardium development	5/4749	13/18670	0.2171	0.5187	0.422	NOTCH1/ANXA2P2/ANXA2/RBPJ/STK3	5
BP	GO:0009437	carnitine metabolic process	5/4749	13/18670	0.2171	0.5187	0.422	TMLHE/CPT1A/POR/ALDH9A1/SLC22A4	5
BP	GO:0010763	positive regulation of fibroblast migration	5/4749	13/18670	0.2171	0.5187	0.422	BAG4/PAK1/PAK3/PRKCE/TGFB1	5
BP	GO:0016024	CDP-diacylglycerol biosynthetic process	5/4749	13/18670	0.2171	0.5187	0.422	AGPAT3/AGPAT2/TAMM41/LCLAT1/GPAT2	5
BP	GO:0031274	positive regulation of pseudopodium assembly	5/4749	13/18670	0.2171	0.5187	0.422	CDC42EP4/CDC42EP1/APC/C15orf62/CDC42	5
BP	GO:0031953	negative regulation of protein autophosphorylation	5/4749	13/18670	0.2171	0.5187	0.422	MVP/PTPRC/CHP1/JUN/ADIPOQ	5
BP	GO:0032488	Cdc42 protein signal transduction	5/4749	13/18670	0.2171	0.5187	0.422	ABCA1/RHOV/RHOU/CDC42/WAS	5
BP	GO:0032536	regulation of cell projection size	5/4749	13/18670	0.2171	0.5187	0.422	PLS1/EZR/TWF2/WNT7A/NEFL	5
BP	GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production	5/4749	13/18670	0.2171	0.5187	0.422	IL1B/IL18/CD80/PAEP/IL23A	5
BP	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway	5/4749	13/18670	0.2171	0.5187	0.422	KANK2/CYP7B1/TP63/LBH/STRN3	5
BP	GO:0033623	regulation of integrin activation	5/4749	13/18670	0.2171	0.5187	0.422	CXCL13/KIF14/SRC/PTGER4/PIEZO1	5
BP	GO:0035563	positive regulation of chromatin binding	5/4749	13/18670	0.2171	0.5187	0.422	CDT1/GMNN/DTX3L/MBD2/DDX11	5
BP	GO:0035589	G protein-coupled purinergic nucleotide receptor signaling pathway	5/4749	13/18670	0.2171	0.5187	0.422	P2RY13/GPR34/P2RY10/P2RY1/PTAFR	5
BP	GO:0035745	T-helper 2 cell cytokine production	5/4749	13/18670	0.2171	0.5187	0.422	NLRP3/RSAD2/ARG1/IL4/GATA3	5
BP	GO:0043247	telomere maintenance in response to DNA damage	5/4749	13/18670	0.2171	0.5187	0.422	TFIP11/ACD/XRCC1/ERCC1/TERF2	5
BP	GO:0045059	positive thymic T cell selection	5/4749	13/18670	0.2171	0.5187	0.422	SRF/CD74/PTPRC/CD3E/ZAP70	5
BP	GO:0045820	negative regulation of glycolytic process	5/4749	13/18670	0.2171	0.5187	0.422	CBFA2T3/SIRT6/STAT3/DDIT4/NUPR1	5
BP	GO:0046040	IMP metabolic process	5/4749	13/18670	0.2171	0.5187	0.422	PFAS/HPRT1/AMPD2/AMPD3/NT5C2	5
BP	GO:0047484	regulation of response to osmotic stress	5/4749	13/18670	0.2171	0.5187	0.422	SLC25A23/ARHGEF2/MICU1/BDKRB2/BAD	5
BP	GO:0050872	white fat cell differentiation	5/4749	13/18670	0.2171	0.5187	0.422	PPARG/PER2/PRDM16/CTBP1/SIRT1	5
BP	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway	5/4749	13/18670	0.2171	0.5187	0.422	CYFIP1/CYFIP2/NTRK3/NTF3/SLC9A6	5
BP	GO:0060312	regulation of blood vessel remodeling	5/4749	13/18670	0.2171	0.5187	0.422	CEACAM1/CST3/FLT4/BCR/TGFB1	5
BP	GO:0060576	intestinal epithelial cell development	5/4749	13/18670	0.2171	0.5187	0.422	CDKN1A/PRDM1/TYMS/SPDEF/C1GALT1	5
BP	GO:0061042	vascular wound healing	5/4749	13/18670	0.2171	0.5187	0.422	MCAM/HPSE/SERPINE1/ADIPOR2/CD34	5
BP	GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	5/4749	13/18670	0.2171	0.5187	0.422	HSPA1A/TLR4/NOD2/NFKBIA/RIPK2	5
BP	GO:0070914	UV-damage excision repair	5/4749	13/18670	0.2171	0.5187	0.422	TREX1/DDB2/XPA/ERCC1/SIRT1	5
BP	GO:0071872	cellular response to epinephrine stimulus	5/4749	13/18670	0.2171	0.5187	0.422	PDE4D/PDE4B/ATP2B4/SIRT2/ADIPOQ	5
BP	GO:0072044	collecting duct development	5/4749	13/18670	0.2171	0.5187	0.422	NOTCH1/AQP2/TFAP2B/DLG5/DACT2	5
BP	GO:0072182	regulation of nephron tubule epithelial cell differentiation	5/4749	13/18670	0.2171	0.5187	0.422	LIF/WWTR1/YAP1/STAT1/GATA3	5
BP	GO:0090308	regulation of methylation-dependent chromatin silencing	5/4749	13/18670	0.2171	0.5187	0.422	MORC2/ZNF304/AICDA/PPHLN1/SETDB1	5
BP	GO:0090646	mitochondrial tRNA processing	5/4749	13/18670	0.2171	0.5187	0.422	PUS1/TRMT10B/TRIT1/TRMT10C/TRNT1	5
BP	GO:0090713	immunological memory process	5/4749	13/18670	0.2171	0.5187	0.422	BCL6/TNFSF4/IL12RB1/CD46/IL23A	5
BP	GO:0098787	mRNA cleavage involved in mRNA processing	5/4749	13/18670	0.2171	0.5187	0.422	ERN1/CPSF1/TUT1/CPSF6/NCBP2	5
BP	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response	5/4749	13/18670	0.2171	0.5187	0.422	BAX/PTPN1/BAK1/ERN1/TMEM33	5
BP	GO:1900225	regulation of NLRP3 inflammasome complex assembly	5/4749	13/18670	0.2171	0.5187	0.422	TLR4/DHX33/TLR6/NLRC3/SIRT2	5
BP	GO:1901550	regulation of endothelial cell development	5/4749	13/18670	0.2171	0.5187	0.422	IL1B/VEGFA/TNF/PROC/CDH5	5
BP	GO:1903140	regulation of establishment of endothelial barrier	5/4749	13/18670	0.2171	0.5187	0.422	IL1B/VEGFA/TNF/PROC/CDH5	5
BP	GO:0042593	glucose homeostasis	67/4749	241/18670	0.2181	0.521	0.4238	PPARG/ICAM1/SRF/RAC1/HK1/PIM3/SLC16A1/NMB/PTCH1/SIRT6/HK2/SMARCB1/CRTC2/STAT3/FFAR2/TIAM1/FABP5/RPS6/ARRB1/ENY2/C2CD2L/SRI/IGF1R/CRY1/SLC2A4/MBD5/LGALS1/FOXO1/CASR/TCF7L2/SMARCA4/TRPM4/NADK/ADIPOR2/OXCT1/PRCP/LRP1/ADIPOR1/CNR1/PARK7/TFAP2B/PRKCE/SIDT2/LRP5L/ZNF236/CYBA/OAS1/BRSK2/GHRL/ADIPOQ/ERN1/GPR21/RAB11FIP5/GCLC/FAM3B/INSR/NUCKS1/SLC9B2/CYP7A1/FFAR1/NDUFAF2/SESN2/PDX1/SYBU/BAD/NME2/SIRT1	67
BP	GO:0006687	glycosphingolipid metabolic process	20/4749	66/18670	0.2185	0.5215	0.4243	NAGA/CTSA/NEU4/GLB1/GM2A/NEU1/BAX/ITGB8/FA2H/ST8SIA1/SUMF1/GBA/B4GALT5/NEU3/GALC/HEXB/SUMF2/ST8SIA3/ALDH5A1/ST6GALNAC6	20
BP	GO:1901880	negative regulation of protein depolymerization	20/4749	66/18670	0.2185	0.5215	0.4243	CAPZB/GSN/CKAP2/SWAP70/TMOD2/CAPG/ARHGEF2/ADD3/SPTBN1/FGF13/CLASP2/TRIOBP/TWF2/SPTAN1/MID1/CAPZA1/TRIM54/VILL/APC/ADD2	20
BP	GO:0032481	positive regulation of type I interferon production	23/4749	77/18670	0.2198	0.5232	0.4257	IRF7/TLR8/HMGB1/NFKB2/PQBP1/IRF5/TLR4/MMP12/XRCC6/POLR3H/TLR2/FLOT1/IRAK1/DHX33/IRF3/IFI16/RIPK2/DDX41/CRCP/STAT1/POLR3GL/ZCCHC3/TRIM15	23
BP	GO:0048644	muscle organ morphogenesis	26/4749	88/18670	0.2199	0.5232	0.4257	LIF/NOTCH1/CNTF/SIRT6/MYLK2/SMAD7/ARID5B/RBPJ/S1PR1/COL11A1/MYBPC3/FKBP1A/RXRA/XIRP2/MYH7/TNNC1/MYOM1/SERP1/BMP10/TPM1/MYH6/TGFB1/TCAP/POU4F1/MYBPC2/ZFPM1	26
BP	GO:0061097	regulation of protein tyrosine kinase activity	26/4749	88/18670	0.2199	0.5232	0.4257	MVP/NTRK2/NEDD9/CSF1R/LRP8/PTPN1/FCGR1A/SRC/FGFR1OP/UNC119/DOCK3/PTK6/PTPRC/SH3BP5L/DUSP22/THY1/GGNBP2/LILRA5/GHRL/PRNP/NCF1/PDGFB/SHC1/FYN/DLG4/PAK2	26
BP	GO:1903725	regulation of phospholipid metabolic process	26/4749	88/18670	0.2199	0.5232	0.4257	KLF4/PDGFA/MTMR3/SOCS2/LDLR/SRC/SOCS3/DGKZ/HTR2A/AMBRA1/PIK3R5/FLT3/VAV2/MTMR9/NOD2/SLA2/CD19/FLT1/FPR2/AGAP2/RAB38/PIK3R4/TNFAIP8L3/TAZ/TGFB1/PDGFB	26
BP	GO:0002429	immune response-activating cell surface receptor signaling pathway	128/4749	473/18670	0.2201	0.5232	0.4257	CD276/RELB/NR4A3/WNK1/SH2B2/FPR1/HCK/RAC1/CLEC10A/PTPN6/CYFIP1/CBFB/FPR3/LGALS3/CEACAM1/BLK/HLA-DQB2/BAX/BTN2A2/SPPL3/WIPF2/LILRA2/TNFRSF21/FOXP3/ERMAP/ACTG1/CARD9/PLEKHA1/CTLA4/FFAR2/FCGR1A/FCN1/CYFIP2/SRC/GCSAM/PSMD8/LILRB4/PDE4D/BTK/DOCK1/PDE4B/PSMD1/PSMD2/PAK1/GRAP2/UBE2N/RPS3/PSMF1/EIF2B3/ARPC1B/GPR33/PAK3/HLA-DPA1/CD79B/VAV2/PTPRC/EZR/CYLD/NFAM1/CD47/RFTN1/DUSP22/LAT/HLA-DRA/KCNN4/ARPC5/MUC1/PSMD9/TXK/SLA2/PSMA5/PLCL2/LIMK1/THY1/CD19/MNDA/RAPGEF1/FPR2/CLEC4D/PSMB7/C3AR1/CR2/ICAM2/FBXW11/TAB1/CRK/PRKCE/PSMD5/ZC3H12A/RABGEF1/ITK/GPR32/CD3E/HLA-DQA2/PSME2/BTRC/CARD11/PSMB5/BTN3A2/PRNP/RIPK2/PRKCB/PRKACB/PSMB4/HLA-DPB1/TRAF6/PSMA3/GCSAML/THEMIS/WASF2/PSMD10/SLC39A10/CDC42/PSMB1/WAS/PSMD7/PSMB3/HHLA2/MAPK1/KLRK1/HLA-DRB1/ZAP70/PSMC5/GATA3/FYN/PAK2/PSMD11/ACTB	128
BP	GO:0007595	lactation	15/4749	48/18670	0.2202	0.5232	0.4257	VDR/VEGFA/OAS2/SOCS2/DHODH/HK2/FOXB1/PAM/USF2/UPRT/DDR1/APRT/CSN2/STAT5A/CCND1	15
BP	GO:0009311	oligosaccharide metabolic process	15/4749	48/18670	0.2202	0.5232	0.4257	NAGA/MPDU1/NEU4/GM2A/NEU1/IDUA/MAN2B1/BRAF/NEU3/HEXB/GAL3ST4/MANBA/ST8SIA3/ST6GALNAC6/MOGS	15
BP	GO:0032648	regulation of interferon-beta production	15/4749	48/18670	0.2202	0.5232	0.4257	IRF7/RELB/TLR8/SIRPA/TIRAP/IRF5/TLR4/TRAIP/TLR2/FLOT1/RNF216/NLRC3/IRF3/RIPK2/PTPRS	15
BP	GO:0044764	multi-organism cellular process	15/4749	48/18670	0.2202	0.5232	0.4257	IRF7/SEC14L1/CCR5/NPLOC4/PGLYRP3/ROMO1/IRF3/BIRC3/C1QBP/KRT6A/TSPAN6/ANKRD17/ZCCHC3/USP17L2/TRIM15	15
BP	GO:0045933	positive regulation of muscle contraction	15/4749	48/18670	0.2202	0.5232	0.4257	ITGA2/SRF/ENO1/ADRA2B/CTTN/RNF207/ABAT/ATP2A1/GSTO1/TRPM4/TACR2/TBXA2R/GHRL/F2R/PTAFR	15
BP	GO:0051653	spindle localization	15/4749	48/18670	0.2202	0.5232	0.4257	ESPL1/SAPCD2/CENPA/GPSM2/ASPM/NUSAP1/PLK1/NUMA1/NDC80/ARHGEF2/HTT/MYH9/ACTR1A/NSFL1C/MCPH1	15
BP	GO:0060324	face development	15/4749	48/18670	0.2202	0.5232	0.4257	SRF/CSRNP1/SKI/ASPH/PLEKHA1/MSX1/TGFB3/ARID5B/MKKS/DLX5/LRP6/TGFB1/RARA/MAPK1/ANKRD11	15
BP	GO:0071897	DNA biosynthetic process	55/4749	196/18670	0.2203	0.5232	0.4257	CENPF/AURKB/CDKN1A/PPARG/DTL/KLF4/NEK2/ISG15/TREX1/PARM1/TYMS/TK1/SMG5/TRIM25/SRC/VCP/PIF1/UBB/POLQ/RFC2/NPLOC4/RPS27A/CCT5/NOP10/PAK3/TERF1/DSCC1/UBA52/POLD4/TNKS2/ACD/CTC1/CHTF8/POLE/POLM/POT1/WRAP53/ADIPOQ/POLG2/SMG6/MAD2L2/ATR/POLN/TINF2/ATM/WRN/MAPK1/PDGFB/KCNK2/FBXO4/POLE2/TERF2/CCT3/SIRT1/DUSP1	55
BP	GO:0031330	negative regulation of cellular catabolic process	73/4749	264/18670	0.2219	0.5268	0.4286	PBK/FURIN/IL10/TIRAP/TIMP4/CTSA/LZTS1/MCL1/TIMP2/ANXA2P2/PML/CBFA2T3/SIRT6/ZFP36/E2F1/MTOR/ANXA2/STAT3/TSPO/SORL1/RYBP/DAP/USP36/HMOX1/RPL5/HNRNPA0/BMF/SDCBP/ATP13A2/CST3/USP19/PSMF1/CIRBP/N4BP1/UBXN1/PDCL3/SGTA/RPL23/PINK1/UBE2G2/MTMR9/QSOX1/NAMPT/ATRAID/DDIT4/RBM46/ATP2B4/CNR1/PARK7/FMR1/TIMP1/SCO1/UCHL5/GSK3A/ELAVL1/SIRT2/LRPPRC/RBM38/MAPKAPK2/ACACB/YBX1/TIMP3/MAP1A/NUPR1/KLHL22/PAM16/RPL11/AXIN2/IL10RA/PHF23/ATG7/NMNAT1/UBAC2	73
BP	GO:0042737	drug catabolic process	40/4749	140/18670	0.2224	0.5278	0.4294	IL4I1/SMOX/CTSH/CYP2S1/SDS/GPX1/PRDX3/MOXD1/GLDC/IDUA/PDXP/MTHFS/ALDH2/PRDX5/HBA2/GCAT/OVGP1/OXCT1/GNPDA1/OXCT2/DLST/CYP2C18/DPYD/MPO/HBG1/PRDX6/FAH/AMPD3/POR/ALDH3B1/HBB/NT5E/HGD/NNT/CYP2D6/AMT/CYP2U1/GSTZ1/NAGK/PRDX1	40
BP	GO:0002688	regulation of leukocyte chemotaxis	33/4749	114/18670	0.2228	0.5285	0.43	CXCL13/VEGFA/WNK1/RAC1/TIRAP/CCR1/DAPK2/LGALS9/HMGB1/CSF1/CXCL10/SERPINE1/SWAP70/CCR6/CCR2/CCL3/CD74/CCL2/AIF1/FPR2/C3AR1/RAC2/PADI2/RARRES2/C1QBP/CCL7/THBS4/DDT/KLRK1/CCL27/VEGFC/IL23A/DUSP1	33
BP	GO:0046847	filopodium assembly	18/4749	59/18670	0.2245	0.5307	0.4317	FSCN1/SRF/CAPZB/SRGAP2/FGD2/TENM1/TGFB3/EZR/ITGA6/ARAP1/RALA/PPP1R16B/FMR1/ARF6/PPP1R9B/BCAS3/CDC42/SPATA13	18
BP	GO:0070527	platelet aggregation	18/4749	59/18670	0.2245	0.5307	0.4317	TYRO3/TSPAN32/PTPN6/CEACAM1/CD9/CLIC1/ACTG1/ABAT/GNAS/BLOC1S4/PRKCA/FERMT3/FIBP/MYH9/HBB/ITGA2B/ILK/ACTB	18
BP	GO:0019985	translesion synthesis	13/4749	41/18670	0.2247	0.5307	0.4317	DTL/ISG15/TRIM25/VCP/UBB/RFC2/NPLOC4/RPS27A/UBA52/POLD4/MAD2L2/POLN/POLE2	13
BP	GO:0030835	negative regulation of actin filament depolymerization	13/4749	41/18670	0.2247	0.5307	0.4317	CAPZB/GSN/SWAP70/TMOD2/CAPG/ADD3/SPTBN1/TRIOBP/TWF2/SPTAN1/CAPZA1/VILL/ADD2	13
BP	GO:0044091	membrane biogenesis	13/4749	41/18670	0.2247	0.5307	0.4317	ANXA2P2/ANXA2/CLIP3/LRP4/SPTBN1/TLCD1/RFTN1/FLOT1/S100A10/PEX3/NLGN4Y/STX2/PEX11A	13
BP	GO:0045616	regulation of keratinocyte differentiation	13/4749	41/18670	0.2247	0.5307	0.4317	VDR/CD109/NOTCH1/CBFB/TP63/ZFP36/NUMA1/SGPP1/CYP27B1/IL20/ZFP36L1/TRIM16/NME2	13
BP	GO:0050873	brown fat cell differentiation	13/4749	41/18670	0.2247	0.5307	0.4317	PLAC8/DUSP10/SH2B2/LRG1/MTOR/PRDM16/SLC2A4/ITGA6/CEBPB/ADIPOQ/PEX11A/METRNL/SIRT1	13
BP	GO:1903053	regulation of extracellular matrix organization	13/4749	41/18670	0.2247	0.5307	0.4317	NOTCH1/FSCN1/ADTRP/CFLAR/CST3/AEBP1/CLASP2/LRP1/DDR1/PHLDB1/TNFRSF1B/TGFB1/HAS2	13
BP	GO:0051346	negative regulation of hydrolase activity	126/4749	466/18670	0.2254	0.5307	0.4317	PPIF/PKMYT1/FURIN/CD109/VEGFA/WNK1/BIRC5/ADORA2A/LMTK3/GPSM1/MICAL1/IFIT1/KLF4/SERPINB6/PTTG1/GAPDH/PLAUR/RFFL/TIMP4/SERPINB8/PPP1R14A/TIMP2/LGALS3/MMP9/YWHAE/RTKN/PPP1R14B/HMSD/TNF/PROS1/NOL3/CDC42SE1/SERPINE1/TNFAIP8/GPX1/BAG4/SORL1/CST5/SRC/MCM2/IFI6/PRDX3/CSTA/SFN/CFLAR/SH2D4A/ARRB1/CST3/BST2/URI1/HERPUD1/BOD1/AMOT/PRDX5/PSMF1/SPINT1/UBXN1/ITIH3/TERF1/PHACTR2/ABCE1/SPOCK3/TIPRL/SFI1/A2M/VTN/GCHFR/MKKS/FKBP1A/GNAI2/STYXL1/CHP1/PARK7/TFAP2B/SH3BP4/CRIM1/BCL2L12/RASA4/TIMP1/CD44/RECK/CEP192/MGAT5/UCHL5/FICD/SIAH2/BIRC3/SERPING1/IFI16/PPP1R8/LCN1/DNAJB6/PPP1R26/TSKS/POR/KDM5A/CST6/CSN2/MNAT1/ELL/TIMP3/SEMA4D/PAM16/BIRC7/SPHK2/PPP1R15A/HDAC9/CARD8/NEIL1/SERPINA4/ARL2/PPP1R9B/SERPINA10/ITIH6/CST1/CST2/BCAS3/CNST/PPP1R2/KLRK1/USP17L2/TFPI/SSPO/PAK2/TERF2/SIRT1	126
BP	GO:0006901	vesicle coating	21/4749	70/18670	0.2264	0.5307	0.4317	SEC13/GORASP1/SEC24D/MCFD2/F5/STX5/SEC16A/CNIH2/ANKRD28/TBC1D20/TMED9/GBF1/TMED10/CTSZ/TRAPPC4/RAB1A/PPP6C/PEF1/PPP6R1/RAB1B/USO1	21
BP	GO:0007004	telomere maintenance via telomerase	21/4749	70/18670	0.2264	0.5307	0.4317	AURKB/NEK2/SMG5/SRC/PIF1/CCT5/NOP10/TERF1/TNKS2/ACD/CTC1/POT1/WRAP53/SMG6/ATR/TINF2/ATM/MAPK1/FBXO4/TERF2/CCT3	21
BP	GO:0034121	regulation of toll-like receptor signaling pathway	21/4749	70/18670	0.2264	0.5307	0.4317	IRF7/GRAMD4/TYRO3/IRF4/TIRAP/HMGB1/TLR4/LILRA2/RSAD2/IRAK3/LRRC14/CD300LF/TLR2/FLOT1/TLR6/NFKBIL1/CYBA/BIRC3/ESR1/PTPRS/PJA2	21
BP	GO:0060395	SMAD protein signal transduction	21/4749	70/18670	0.2264	0.5307	0.4317	SKI/TGFB3/WWTR1/FAM89B/SPTBN1/ATOH8/BTBD11/GDF7/JUN/VIM/SLC33A1/SMAD1/LEFTY1/LNPEP/BMP10/BMP3/NUP93/RBPMS/FOS/TGFB1/VEPH1	21
BP	GO:0061515	myeloid cell development	21/4749	70/18670	0.2264	0.5307	0.4317	KLF2/SRF/PTPN6/BCL6/ZNF385A/ANXA2P2/LRRK1/ANXA2/SRC/RPS6/FAM20C/TLR2/MAEA/ERCC2/TYROBP/PIP4K2A/ARID4A/TNFSF11/WASF2/SLC9B2/ZFPM1	21
BP	GO:0007031	peroxisome organization	24/4749	81/18670	0.2267	0.5307	0.4317	MPV17/USP9X/ABCD1/SLC27A2/UBB/HMGCL/EPHX2/ACOX2/TYSND1/RPS27A/ACOT8/UBA52/AMACR/PEX2/PEX3/PEX5/PEX11A/GSTK1/NUDT19/PECR/PEX13/PEX1/DECR2/ZFAND6	24
BP	GO:0014032	neural crest cell development	24/4749	81/18670	0.2267	0.5307	0.4317	TWIST1/CORO1C/SEMA4C/SEMA7A/SEMA3G/ALX1/SEMA6C/SEMA6B/EFNB1/CYP26C1/JAG1/FAM172A/CFL1/NOLC1/SOX8/SOX11/SEMA3B/SEMA5B/SEMA4D/SEMA5A/MAPK1/RDH10/PEF1/LAMA5	24
BP	GO:0021766	hippocampus development	24/4749	81/18670	0.2267	0.5307	0.4317	KIF14/NR4A3/SRF/CDK5/BBS2/MFSD2A/YWHAE/NF2/LRP8/XRN2/NKX2-1/EIF2B3/FGF13/EZH2/MKKS/DRD1/ATP2B4/CRK/XRCC1/HSD3B2/PTPRS/NEFL/UBA6/RARA	24
BP	GO:0034109	homotypic cell-cell adhesion	24/4749	81/18670	0.2267	0.5307	0.4317	TYRO3/TSPAN32/PTPN6/DSC2/CEACAM1/CD9/CLIC1/ACTG1/ABAT/GNAS/BLOC1S4/LGALS1/CEACAM5/PRKCA/FERMT3/CD99L2/ZNF703/FIBP/MYH9/HBB/ITGA2B/TNFSF11/ILK/ACTB	24
BP	GO:0060761	negative regulation of response to cytokine stimulus	24/4749	81/18670	0.2267	0.5307	0.4317	PPARG/KLF4/IL1RN/TREX1/RFFL/NOL3/MMP12/IL1R2/PARP14/TRAIP/IRAK3/PTPRC/SIGIRR/SCRIB/ARG1/SAMHD1/RABGEF1/CNOT7/YTHDF3/PADI2/PIAS4/ADIPOQ/CARD8/ZNF675	24
BP	GO:0009219	pyrimidine deoxyribonucleotide metabolic process	7/4749	20/18670	0.2281	0.5307	0.4317	DCTPP1/TYMS/CMPK2/DTYMK/DCTD/NEIL1/OGG1	7
BP	GO:0010592	positive regulation of lamellipodium assembly	7/4749	20/18670	0.2281	0.5307	0.4317	FSCN1/RAC1/MTOR/TWF2/RAC2/WASF2/CDC42	7
BP	GO:0030220	platelet formation	7/4749	20/18670	0.2281	0.5307	0.4317	CASP9/SRF/PTPN6/ZNF385A/WDR1/MYH9/ZFPM1	7
BP	GO:0032816	positive regulation of natural killer cell activation	7/4749	20/18670	0.2281	0.5307	0.4317	IL18/TOX/AXL/HLA-E/LAMP1/TYROBP/IL23A	7
BP	GO:0033194	response to hydroperoxide	7/4749	20/18670	0.2281	0.5307	0.4317	GPX1/AIF1/SP1/TP53INP1/XRCC1/DAPK1/STX2	7
BP	GO:0042228	interleukin-8 biosynthetic process	7/4749	20/18670	0.2281	0.5307	0.4317	KLF4/BCL3/TLR8/CLEC7A/TNF/TLR4/CD74	7
BP	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process	7/4749	20/18670	0.2281	0.5307	0.4317	CLEC7A/TNFRSF8/CYBB/TLR4/CCR2/MAPKAPK2/TYROBP	7
BP	GO:0045655	regulation of monocyte differentiation	7/4749	20/18670	0.2281	0.5307	0.4317	IRF7/FES/CSF1/ZBTB46/CD74/JUN/ZFP36L1	7
BP	GO:0046823	negative regulation of nucleocytoplasmic transport	7/4749	20/18670	0.2281	0.5307	0.4317	CDK5/NUP153/CHP1/PARK7/CABP1/RAB23/BARD1	7
BP	GO:0070828	heterochromatin organization	7/4749	20/18670	0.2281	0.5307	0.4317	SETD7/SIRT6/SNAI1/PRDM16/CDKN2A/HELLS/CENPV	7
BP	GO:0072234	metanephric nephron tubule development	7/4749	20/18670	0.2281	0.5307	0.4317	LIF/WWTR1/PKD2/SOX8/YAP1/UMOD/STAT1	7
BP	GO:1900017	positive regulation of cytokine production involved in inflammatory response	7/4749	20/18670	0.2281	0.5307	0.4317	IL17A/CLEC7A/TLR4/NOD2/TLR6/IL17RC/CD6	7
BP	GO:1900424	regulation of defense response to bacterium	7/4749	20/18670	0.2281	0.5307	0.4317	GRN/HAVCR2/SYT11/CYBA/SIRT2/KLK5/SIGLEC11	7
BP	GO:1903599	positive regulation of autophagy of mitochondrion	7/4749	20/18670	0.2281	0.5307	0.4317	HK2/HTT/SMURF1/PINK1/GBA/PARK7/VPS13D	7
BP	GO:0007435	salivary gland morphogenesis	11/4749	34/18670	0.2283	0.5307	0.4317	PDGFA/TNF/TGM2/PLXNA1/TGFB3/PLXND1/FGF8/EDAR/TGFB1/LAMA5/ESRP2	11
BP	GO:0009452	7-methylguanosine RNA capping	11/4749	34/18670	0.2283	0.5307	0.4317	CDK7/POLR2I/ERCC2/GTF2H2/POLR2C/GTF2H1/MNAT1/POLR2J/GTF2H5/NCBP2/POLR2A	11
BP	GO:0010922	positive regulation of phosphatase activity	11/4749	34/18670	0.2283	0.5307	0.4317	ITGA2/MTOR/RIPK3/PPARGC1B/CD33/MTMR9/PTPRC/ITGA1/PPP1R15A/SLC39A10/PPP1R12A	11
BP	GO:0016601	Rac protein signal transduction	11/4749	34/18670	0.2283	0.5307	0.4317	RAC1/CYFIP1/RHOG/TIAM1/STMN3/AIF1/CRK/RAC2/RHOU/ARF6/WASF2	11
BP	GO:0017004	cytochrome complex assembly	11/4749	34/18670	0.2283	0.5307	0.4317	SCO2/COX17/PET117/COX18/COA3/SCO1/CYBA/FASTKD3/COA5/COA4/TTC19	11
BP	GO:0032212	positive regulation of telomere maintenance via telomerase	11/4749	34/18670	0.2283	0.5307	0.4317	AURKB/NEK2/CCT5/TNKS2/ACD/POT1/ATR/ATM/MAPK1/FBXO4/CCT3	11
BP	GO:0032594	protein transport within lipid bilayer	11/4749	34/18670	0.2283	0.5307	0.4317	REEP2/HIP1/GRIPAP1/SNAP47/ATP1B1/STX1B/RILPL2/CACNG3/RFTN1/AP3D1/SCRIB	11
BP	GO:0033120	positive regulation of RNA splicing	11/4749	34/18670	0.2283	0.5307	0.4317	RBM22/HSPA1A/NUP98/CIRBP/SF3B4/PRPF19/RBMY1B/PRDX6/ERN1/RBM3/POLR2A	11
BP	GO:0036260	RNA capping	11/4749	34/18670	0.2283	0.5307	0.4317	CDK7/POLR2I/ERCC2/GTF2H2/POLR2C/GTF2H1/MNAT1/POLR2J/GTF2H5/NCBP2/POLR2A	11
BP	GO:0071402	cellular response to lipoprotein particle stimulus	11/4749	34/18670	0.2283	0.5307	0.4317	PPARG/CD68/ABCG1/CD9/TLR4/ADTRP/LDLR/CASR/ABCA1/TLR6/SREBF2	11
BP	GO:0045137	development of primary sexual characteristics	62/4749	223/18670	0.2283	0.5307	0.4317	VEGFA/ASPM/ICAM1/NTRK1/FANCG/KIF18A/HSPA5/BRCA2/BAX/NASP/PLEKHA1/HYAL3/SRC/NUDT1/NKX2-1/ARRB1/RRM1/DMC1/RAB13/UBB/ARID5B/FGF9/BIK/SDC1/PATZ1/TBC1D20/CBX2/MKKS/FNDC3A/SOX8/BASP1/UBE3A/NCOA4/REC8/WDR19/CITED2/CEBPB/IRX5/BCL2L1/ADAM15/ZNF830/CTNNA1/RBMY1B/SFRP1/ESR1/KDM5A/TNFSF10/HOXA11/INSR/NUPR1/FGF8/ARID4A/ADAMTS1/ATM/WDR48/TMF1/RARA/CCND1/RDH10/GATA3/ERCC1/SIRT1	62
BP	GO:0033500	carbohydrate homeostasis	67/4749	242/18670	0.2297	0.5307	0.4317	PPARG/ICAM1/SRF/RAC1/HK1/PIM3/SLC16A1/NMB/PTCH1/SIRT6/HK2/SMARCB1/CRTC2/STAT3/FFAR2/TIAM1/FABP5/RPS6/ARRB1/ENY2/C2CD2L/SRI/IGF1R/CRY1/SLC2A4/MBD5/LGALS1/FOXO1/CASR/TCF7L2/SMARCA4/TRPM4/NADK/ADIPOR2/OXCT1/PRCP/LRP1/ADIPOR1/CNR1/PARK7/TFAP2B/PRKCE/SIDT2/LRP5L/ZNF236/CYBA/OAS1/BRSK2/GHRL/ADIPOQ/ERN1/GPR21/RAB11FIP5/GCLC/FAM3B/INSR/NUCKS1/SLC9B2/CYP7A1/FFAR1/NDUFAF2/SESN2/PDX1/SYBU/BAD/NME2/SIRT1	67
BP	GO:0098781	ncRNA transcription	31/4749	107/18670	0.2299	0.5307	0.4317	GTF3C4/MTOR/SMARCB1/POU2F1/SNAPC5/GTF3C2/CDK7/SMARCA4/CCNT2/NCL/SP1/POLR2I/RPRD1A/TAF11/CCNK/NPM3/INTS12/POLR2C/DDX11/TAF6/GTF3C6/ELL/POLR2J/IPPK/SIRT7/NCBP2/SNAPC3/POU2F2/POLR2A/POLR1B/SPIN1	31
BP	GO:0006730	one-carbon metabolic process	9/4749	27/18670	0.23	0.5307	0.4317	MTHFD2/MTHFD1L/SFXN1/TYMS/MTHFS/DHFR/MTHFD1/GNMT/SFXN3	9
BP	GO:0032201	telomere maintenance via semi-conservative replication	9/4749	27/18670	0.23	0.5307	0.4317	FEN1/UPF1/RFC2/TERF1/POLD4/POLE/DNA2/POLE2/TERF2	9
BP	GO:0036151	phosphatidylcholine acyl-chain remodeling	9/4749	27/18670	0.23	0.5307	0.4317	PLBD1/PLA2G12A/LPCAT2/TMEM86B/LPCAT3/LPCAT4/PLA2G2A/PLA2G5/PLB1	9
BP	GO:0036475	neuron death in response to oxidative stress	9/4749	27/18670	0.23	0.5307	0.4317	NR4A3/IL10/MCL1/TLR4/ATF4/PINK1/TLR6/PARK7/ATG7	9
BP	GO:0045671	negative regulation of osteoclast differentiation	9/4749	27/18670	0.23	0.5307	0.4317	TLR4/PIAS3/LILRB4/CCL3/TOB2/SFRP1/IL4/ZNF675/TCTA	9
BP	GO:0071450	cellular response to oxygen radical	9/4749	27/18670	0.23	0.5307	0.4317	TNF/NQO1/DHFR/FANCC/PARK7/MPO/CCS/ADPRHL2/PRDX1	9
BP	GO:0071451	cellular response to superoxide	9/4749	27/18670	0.23	0.5307	0.4317	TNF/NQO1/DHFR/FANCC/PARK7/MPO/CCS/ADPRHL2/PRDX1	9
BP	GO:0071514	genetic imprinting	9/4749	27/18670	0.23	0.5307	0.4317	GNAS/PRMT7/EED/ASIP/PCGF6/NDN/PCGF5/ARID4A/ZFP57	9
BP	GO:1904357	negative regulation of telomere maintenance via telomere lengthening	9/4749	27/18670	0.23	0.5307	0.4317	SRC/PIF1/TERF1/TNKS2/ACD/CTC1/POT1/TINF2/TERF2	9
BP	GO:0061041	regulation of wound healing	42/4749	148/18670	0.2305	0.5307	0.4317	HBEGF/CD109/CDKN1A/DUSP10/PDGFA/PLAUR/HPSE/CLEC7A/ANXA2P2/CEACAM1/CD9/TNFRSF12A/PROS1/TMPRSS6/TLR4/PROC/PLAU/SERPINE1/MTOR/ADTRP/ANXA2/VKORC1/PLAT/ABAT/PRKCA/CLASP2/ANXA5/VTN/ENPP4/CRK/PRKCE/KLKB1/TBXA2R/SERPING1/INSL3/F3/CD34/MYH9/F2R/PPARD/PDGFB/TFPI	42
BP	GO:0006301	postreplication repair	16/4749	52/18670	0.2306	0.5307	0.4317	DTL/ISG15/UBE2A/UBE2B/TRIM25/VCP/UBB/UBE2N/RFC2/NPLOC4/RPS27A/UBA52/POLD4/MAD2L2/POLN/POLE2	16
BP	GO:0090277	positive regulation of peptide hormone secretion	28/4749	96/18670	0.2318	0.5307	0.4317	RAC1/BLK/ABAT/ARRB1/C2CD2L/SRI/CASR/TCF7L2/TRPM4/NADK/OXCT1/PFKFB2/PSMD9/LRP1/SIRT3/ILDR1/PRKCE/GLUD1/GHRL/SERP1/DOC2B/TNFSF11/PPARD/FFAR1/PDX1/GIPR/SYBU/BAD	28
BP	GO:0014031	mesenchymal cell development	25/4749	85/18670	0.2332	0.5307	0.4317	TWIST1/NOTCH1/CORO1C/SEMA4C/SEMA7A/SEMA3G/ALX1/SEMA6C/SEMA6B/EFNB1/CYP26C1/JAG1/FAM172A/CFL1/NOLC1/SOX8/SOX11/SEMA3B/SEMA5B/SEMA4D/SEMA5A/MAPK1/RDH10/PEF1/LAMA5	25
BP	GO:0070373	negative regulation of ERK1 and ERK2 cascade	22/4749	74/18670	0.2338	0.5307	0.4317	LIF/DUSP10/DUSP4/KLF4/DUSP6/SIRPA/ATF3/TLR4/CHRNA10/BTN2A2/PTPN1/ARRB1/SYNJ2BP/PTPRC/EZR/NDRG2/SIRT3/RAPGEF1/C3orf33/ADIPOQ/TIMP3/DUSP1	22
BP	GO:1900076	regulation of cellular response to insulin stimulus	22/4749	74/18670	0.2338	0.5307	0.4317	IL1B/MZB1/SOCS2/PTPN1/ESRRA/SORL1/SRC/SOCS3/PAK1/ENHO/FFAR3/ADIPOR1/SLA2/GNAI2/GSK3A/BGLAP/GPR21/PRKCB/NUCKS1/GKAP1/USO1/SIRT1	22
BP	GO:1900182	positive regulation of protein localization to nucleus	22/4749	74/18670	0.2338	0.5307	0.4317	LIF/GTSE1/CDK1/RBM22/PLK1/SRC/DTX3L/GLIS2/CCT5/PARK7/EFCAB7/MCRS1/ECT2/ZC3H12A/BAG3/CD2AP/EIF2AK3/TGFB1/MAPK1/SESN2/FYN/CCT3	22
BP	GO:0000012	single strand break repair	4/4749	10/18670	0.2344	0.5307	0.4317	APLF/XRCC1/TERF2/SIRT1	4
BP	GO:0001660	fever generation	4/4749	10/18670	0.2344	0.5307	0.4317	IL1B/TNF/CNR1/TNFSF11	4
BP	GO:0001840	neural plate development	4/4749	10/18670	0.2344	0.5307	0.4317	PTCH1/DVL1/EPB41L5/FGF8	4
BP	GO:0006171	cAMP biosynthetic process	4/4749	10/18670	0.2344	0.5307	0.4317	ADCY4/ADCY6/ADCY3/ADCY9	4
BP	GO:0006188	IMP biosynthetic process	4/4749	10/18670	0.2344	0.5307	0.4317	PFAS/HPRT1/AMPD2/AMPD3	4
BP	GO:0006222	UMP biosynthetic process	4/4749	10/18670	0.2344	0.5307	0.4317	DHODH/UPRT/CMPK1/UCK2	4
BP	GO:0006228	UTP biosynthetic process	4/4749	10/18670	0.2344	0.5307	0.4317	NME4/NME3/NME9/NME2	4
BP	GO:0006285	base-excision repair, AP site formation	4/4749	10/18670	0.2344	0.5307	0.4317	MPG/NEIL1/OGG1/MUTYH	4
BP	GO:0006930	substrate-dependent cell migration, cell extension	4/4749	10/18670	0.2344	0.5307	0.4317	MYH10/CTTN/SDCBP/CD2AP	4
BP	GO:0006971	hypotonic response	4/4749	10/18670	0.2344	0.5307	0.4317	ITGA2/TSPO/SLC12A6/SLC12A5	4
BP	GO:0009173	pyrimidine ribonucleoside monophosphate metabolic process	4/4749	10/18670	0.2344	0.5307	0.4317	DHODH/UPRT/CMPK1/UCK2	4
BP	GO:0009174	pyrimidine ribonucleoside monophosphate biosynthetic process	4/4749	10/18670	0.2344	0.5307	0.4317	DHODH/UPRT/CMPK1/UCK2	4
BP	GO:0009396	folic acid-containing compound biosynthetic process	4/4749	10/18670	0.2344	0.5307	0.4317	MTHFD1L/MTHFS/DHFR/MTHFD1	4
BP	GO:0010944	negative regulation of transcription by competitive promoter binding	4/4749	10/18670	0.2344	0.5307	0.4317	SMAD7/MUC1/BHLHE41/MAD2L2	4
BP	GO:0014041	regulation of neuron maturation	4/4749	10/18670	0.2344	0.5307	0.4317	BCL11A/MTOR/TBX6/RAC3	4
BP	GO:0018242	protein O-linked glycosylation via serine	4/4749	10/18670	0.2344	0.5307	0.4317	GALNT2/MGAT5B/GALNT1/POGLUT1	4
BP	GO:0021694	cerebellar Purkinje cell layer formation	4/4749	10/18670	0.2344	0.5307	0.4317	FAIM2/CEND1/AGTPBP1/LDB1	4
BP	GO:0032000	positive regulation of fatty acid beta-oxidation	4/4749	10/18670	0.2344	0.5307	0.4317	TWIST1/ABCD1/ABCD2/CPT1A	4
BP	GO:0032070	regulation of deoxyribonuclease activity	4/4749	10/18670	0.2344	0.5307	0.4317	HMGB1/RPS3/DDX11/SIRT1	4
BP	GO:0032308	positive regulation of prostaglandin secretion	4/4749	10/18670	0.2344	0.5307	0.4317	IL1B/MAP2K6/TNFSF11/P2RX7	4
BP	GO:0032328	alanine transport	4/4749	10/18670	0.2344	0.5307	0.4317	SLC36A1/SLC1A4/SLC38A2/SLC36A4	4
BP	GO:0032464	positive regulation of protein homooligomerization	4/4749	10/18670	0.2344	0.5307	0.4317	BMF/CLU/BIK/BID	4
BP	GO:0032836	glomerular basement membrane development	4/4749	10/18670	0.2344	0.5307	0.4317	SULF2/MYO1E/MPV17/NID1	4
BP	GO:0033690	positive regulation of osteoblast proliferation	4/4749	10/18670	0.2344	0.5307	0.4317	HPSE/CTHRC1/SOX8/TMEM119	4
BP	GO:0034135	regulation of toll-like receptor 2 signaling pathway	4/4749	10/18670	0.2344	0.5307	0.4317	TIRAP/TLR6/CYBA/PJA2	4
BP	GO:0035090	maintenance of apical/basal cell polarity	4/4749	10/18670	0.2344	0.5307	0.4317	ANK1/WDR1/LIN7C/PDZD11	4
BP	GO:0035646	endosome to melanosome transport	4/4749	10/18670	0.2344	0.5307	0.4317	BLOC1S6/RAB32/AP3D1/RAB38	4
BP	GO:0042536	negative regulation of tumor necrosis factor biosynthetic process	4/4749	10/18670	0.2344	0.5307	0.4317	IL10/BCL3/GHRL/IL4	4
BP	GO:0042989	sequestering of actin monomers	4/4749	10/18670	0.2344	0.5307	0.4317	GSN/TMSB4Y/TWF2/TMSB15A	4
BP	GO:0043485	endosome to pigment granule transport	4/4749	10/18670	0.2344	0.5307	0.4317	BLOC1S6/RAB32/AP3D1/RAB38	4
BP	GO:0044359	modulation of molecular function in other organism	4/4749	10/18670	0.2344	0.5307	0.4317	ANXA2P2/ANXA2/SCRIB/NUCKS1	4
BP	GO:0045199	maintenance of epithelial cell apical/basal polarity	4/4749	10/18670	0.2344	0.5307	0.4317	ANK1/WDR1/LIN7C/PDZD11	4
BP	GO:0045348	positive regulation of MHC class II biosynthetic process	4/4749	10/18670	0.2344	0.5307	0.4317	IL10/TLR4/IL4/SIRT1	4
BP	GO:0045876	positive regulation of sister chromatid cohesion	4/4749	10/18670	0.2344	0.5307	0.4317	SFPQ/FEN1/DDX11/SMC5	4
BP	GO:0046049	UMP metabolic process	4/4749	10/18670	0.2344	0.5307	0.4317	DHODH/UPRT/CMPK1/UCK2	4
BP	GO:0046532	regulation of photoreceptor cell differentiation	4/4749	10/18670	0.2344	0.5307	0.4317	NOTCH1/CNTF/TUG1/SOX8	4
BP	GO:0046710	GDP metabolic process	4/4749	10/18670	0.2344	0.5307	0.4317	TJP2/LRGUK/CARD11/GUK1	4
BP	GO:0048262	determination of dorsal/ventral asymmetry	4/4749	10/18670	0.2344	0.5307	0.4317	GREM2/DDIT3/AIDA/CER1	4
BP	GO:0048382	mesendoderm development	4/4749	10/18670	0.2344	0.5307	0.4317	SSBP3/ZFP36L1/FGF8/LDB1	4
BP	GO:0048757	pigment granule maturation	4/4749	10/18670	0.2344	0.5307	0.4317	BLOC1S6/RAB32/AP3D1/RAB38	4
BP	GO:0051014	actin filament severing	4/4749	10/18670	0.2344	0.5307	0.4317	SRGAP2/GSN/FMNL1/MYH9	4
BP	GO:0051901	positive regulation of mitochondrial depolarization	4/4749	10/18670	0.2344	0.5307	0.4317	MLLT11/TSPO/CCK/P2RX7	4
BP	GO:0052205	modulation of molecular function in other organism involved in symbiotic interaction	4/4749	10/18670	0.2344	0.5307	0.4317	ANXA2P2/ANXA2/SCRIB/NUCKS1	4
BP	GO:0061140	lung secretory cell differentiation	4/4749	10/18670	0.2344	0.5307	0.4317	ASCL1/NKX2-1/SPDEF/IL13	4
BP	GO:0070314	G1 to G0 transition	4/4749	10/18670	0.2344	0.5307	0.4317	EZH2/CYP27B1/ZNF503/RAB11FIP4	4
BP	GO:0070391	response to lipoteichoic acid	4/4749	10/18670	0.2344	0.5307	0.4317	TIRAP/TLR4/TLR2/RIPK2	4
BP	GO:0071223	cellular response to lipoteichoic acid	4/4749	10/18670	0.2344	0.5307	0.4317	TIRAP/TLR4/TLR2/RIPK2	4
BP	GO:0071233	cellular response to leucine	4/4749	10/18670	0.2344	0.5307	0.4317	MTOR/UBR2/KLHL22/SESN2	4
BP	GO:0072610	interleukin-12 secretion	4/4749	10/18670	0.2344	0.5307	0.4317	MAPK11/TLR8/LGALS9/LILRA5	4
BP	GO:0090205	positive regulation of cholesterol metabolic process	4/4749	10/18670	0.2344	0.5307	0.4317	ABCG1/POR/LDLRAP1/CYP7A1	4
BP	GO:0090309	positive regulation of methylation-dependent chromatin silencing	4/4749	10/18670	0.2344	0.5307	0.4317	MORC2/ZNF304/PPHLN1/SETDB1	4
BP	GO:0098722	asymmetric stem cell division	4/4749	10/18670	0.2344	0.5307	0.4317	TEAD3/ETV5/ARHGEF2/FGF13	4
BP	GO:0098917	retrograde trans-synaptic signaling	4/4749	10/18670	0.2344	0.5307	0.4317	SYT4/FABP5/CNR1/PLCB1	4
BP	GO:0140052	cellular response to oxidised low-density lipoprotein particle stimulus	4/4749	10/18670	0.2344	0.5307	0.4317	CD68/TLR4/ADTRP/TLR6	4
BP	GO:1900122	positive regulation of receptor binding	4/4749	10/18670	0.2344	0.5307	0.4317	ANXA2P2/MMP9/ANXA2/PLCL2	4
BP	GO:1900222	negative regulation of amyloid-beta clearance	4/4749	10/18670	0.2344	0.5307	0.4317	SRF/TNF/LRPAP1/IFNGR1	4
BP	GO:1900426	positive regulation of defense response to bacterium	4/4749	10/18670	0.2344	0.5307	0.4317	GRN/HAVCR2/CYBA/KLK5	4
BP	GO:1902101	positive regulation of metaphase/anaphase transition of cell cycle	4/4749	10/18670	0.2344	0.5307	0.4317	ESPL1/CDT1/DLGAP5/ANAPC11	4
BP	GO:1902237	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	4/4749	10/18670	0.2344	0.5307	0.4317	SERINC3/PMAIP1/DDIT3/SIRT1	4
BP	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA	4/4749	10/18670	0.2344	0.5307	0.4317	ZC3H12A/ESR1/TGFB1/NCOR1	4
BP	GO:1903897	regulation of PERK-mediated unfolded protein response	4/4749	10/18670	0.2344	0.5307	0.4317	HSPA5/PTPN1/PPP1R15A/TMEM33	4
BP	GO:1904350	regulation of protein catabolic process in the vacuole	4/4749	10/18670	0.2344	0.5307	0.4317	LDLR/ATP13A2/LRP1/GBA	4
BP	GO:1904896	ESCRT complex disassembly	4/4749	10/18670	0.2344	0.5307	0.4317	CHMP2B/IST1/CHMP1A/CHMP2A	4
BP	GO:1904903	ESCRT III complex disassembly	4/4749	10/18670	0.2344	0.5307	0.4317	CHMP2B/IST1/CHMP1A/CHMP2A	4
BP	GO:2000035	regulation of stem cell division	4/4749	10/18670	0.2344	0.5307	0.4317	NAP1L2/CDK2AP2/PRDM15/LBH	4
BP	GO:2000271	positive regulation of fibroblast apoptotic process	4/4749	10/18670	0.2344	0.5307	0.4317	TP63/BID/SFRP1/STK17B	4
BP	GO:2000317	negative regulation of T-helper 17 type immune response	4/4749	10/18670	0.2344	0.5307	0.4317	FOXP3/SMAD7/IL27RA/ZC3H12A	4
BP	GO:0010951	negative regulation of endopeptidase activity	69/4749	250/18670	0.2348	0.531	0.432	FURIN/CD109/VEGFA/BIRC5/ADORA2A/MICAL1/KLF4/SERPINB6/PTTG1/GAPDH/PLAUR/RFFL/TIMP4/SERPINB8/TIMP2/MMP9/YWHAE/HMSD/PROS1/NOL3/SERPINE1/TNFAIP8/GPX1/SORL1/CST5/SRC/IFI6/PRDX3/CSTA/SFN/CFLAR/ARRB1/CST3/BST2/HERPUD1/PRDX5/PSMF1/SPINT1/ITIH3/SPOCK3/A2M/VTN/PARK7/TFAP2B/CRIM1/BCL2L12/TIMP1/CD44/RECK/UCHL5/SIAH2/BIRC3/SERPING1/IFI16/LCN1/DNAJB6/POR/CST6/CSN2/TIMP3/BIRC7/CARD8/SERPINA4/SERPINA10/ITIH6/CST1/CST2/TFPI/PAK2	69
BP	GO:0030072	peptide hormone secretion	69/4749	250/18670	0.2348	0.531	0.432	IL1B/RAC1/IL1RN/PIM3/SLC16A1/TNF/BLK/FFAR2/MYO5A/TIAM1/ABAT/ARRB1/ENY2/C2CD2L/SRI/ENHO/PER2/FFAR3/CASR/TCF7L2/PRKCA/TRPM4/NADK/ANXA5/OXCT1/PFKFB2/PSMD9/LRP1/CACNA2D2/SIRT3/ILDR1/CNR1/PARK7/TFAP2B/ACVR1C/SLC25A5/ACVR2B/SNX19/CAMK2G/PRKCE/TACR2/SIDT2/LRP5L/ARNTL/GLUD1/BRSK2/SFRP1/GHRL/KCNG2/CPT1A/ARL2BP/RAB11FIP5/SERP1/DOC2B/FAM3B/RAB1A/SLC25A4/PFKL/TNFSF11/ARL2/NPFF/PPARD/SLC9B2/FFAR1/NDUFAF2/PDX1/GIPR/SYBU/BAD	69
BP	GO:0071383	cellular response to steroid hormone stimulus	69/4749	250/18670	0.2348	0.531	0.432	VDR/NR4A1/NR4A3/PPARG/ICAM1/NR3C2/CASP9/KANK2/PMEPA1/CBFB/YWHAH/DNAJA1/CYP7B1/TGFB1I1/TP63/THRA/EIF4EBP1/ZFP36/ADTRP/ESRRA/NR3C1/PAQR7/SRC/PPARGC1B/CFLAR/TRIP4/CRY1/PAK1/URI1/FLT3/FOXO1/ZFP36L2/RORC/CARM1/CDK7/SMARCA4/PIAS1/DDIT4/KLF9/ARG1/RXRA/CREBRF/ARID1A/PARK7/PPP5C/UBE3A/NCOA4/DDX17/DDX54/PIAS2/ARNTL/YAP1/PADI2/SFRP1/TAF7/ESR1/ZFP36L1/DEFA1B/AKAP13/LBH/PPARD/TGFB1/STRN3/NR2C1/RARA/NCOR1/TFPI/MGARP/SIRT1	69
BP	GO:0035305	negative regulation of dephosphorylation	32/4749	111/18670	0.235	0.5315	0.4324	PKMYT1/WNK1/LMTK3/PPP1R14A/LGALS3/YWHAE/PPP1R14B/TNF/BAG4/SWAP70/SH2D4A/URI1/BOD1/PHACTR2/TIPRL/SFI1/FKBP1A/GNAI2/STYXL1/PPP1R16B/CHP1/CEP192/MGAT5/PPP1R8/PPP1R26/TSKS/ELL/SEMA4D/PPP1R15A/PPP1R9B/CNST/PPP1R2	32
BP	GO:0002833	positive regulation of response to biotic stimulus	14/4749	45/18670	0.2365	0.5344	0.4348	GRN/HAVCR2/CD180/PRKCA/ARG1/CYBA/RIPK2/LRSAM1/KLK5/TRAF6/ANKRD17/ZCCHC3/USP17L2/TRIM15	14
BP	GO:1902743	regulation of lamellipodium organization	14/4749	45/18670	0.2365	0.5344	0.4348	FSCN1/RAC1/CORO1C/CAPZB/MTOR/SRC/CORO1B/TWF2/CD44/RAC2/FER/WASF2/CDC42/WAS	14
BP	GO:0007517	muscle organ development	111/4749	410/18670	0.2368	0.5348	0.4351	EGR1/EGR3/CENPF/TWIST1/EGR2/LIF/HBEGF/MAPK11/NOTCH1/TP73/CDK1/SMTN/HLF/EVC/EPHB1/CNTF/GPC1/CDK5/ATF3/SIRT6/SGCB/POU6F1/SKI/CXCL10/SVIL/MTOR/ASB2/GPX1/WNT10B/MYLK2/MSX1/SMAD7/PIM1/CCNB1/BTBD1/PARP2/HOMER1/CFLAR/MYL6/ZNF609/MAPK12/USP19/SRI/PAK1/ARID5B/KAT2A/FGF9/RBPJ/ZFHX3/HLX/FKTN/S1PR1/ZNF689/TIFAB/COL11A1/CCNT2/MEF2D/STAC3/MRAS/FLOT1/MYBPC3/FKBP1A/RXRA/XIRP2/SOX8/MYH7/EMD/BASP1/CHRNA1/MEF2B/DDX17/PRR14/TNNC1/EID2/VGLL2/SOX11/ARNTL/YAP1/SPEG/MYL6B/GSK3A/SIRT2/MYOM1/SERP1/UTRN/EID2B/BMP10/NUPR1/FGF8/IGSF8/TPM1/HDAC9/MSC/HMG20B/FOS/POPDC3/DLL1/TEAD4/TAZ/GPCPD1/MYH6/TGFB1/TCAP/POU4F1/MYBPC2/MAPK1/LAMA5/MIR17HG/KCNK2/ZFPM1/SIRT1	111
BP	GO:0019216	regulation of lipid metabolic process	111/4749	410/18670	0.2368	0.5348	0.4351	VDR/EGR1/G0S2/TWIST1/TIAM2/IL1B/NR4A3/PPARG/ABCG1/KLF4/PDGFA/PDPR/HELZ2/TREX1/CEACAM1/MTMR3/SOCS2/THRA/TNF/TNFRSF21/MTOR/LDLR/ABCD1/PMVK/FDPS/TSPO/SORL1/SRC/FITM2/SCD/SOCS3/SNAI1/ABCD2/DGKZ/FABP5/HTR2A/CD74/ENHO/EPHX2/ACSL1/AMBRA1/PIK3R5/FLT3/TYSND1/RORC/CARM1/PRKAB2/VAV2/MTMR9/ADIPOR2/ABCA1/LMF1/SLC45A3/INSIG1/NOD2/SP1/ADIPOR1/SLA2/CD19/FLT1/RXRA/PRKAG2/CNR1/FPR2/CYP27B1/ABCB4/ACER1/AGAP2/PIBF1/PRKCE/PLIN2/DDX20/RAB38/RBL2/EEF1A2/SQLE/CREBL2/RARRES2/ADM/ADIPOQ/CPT1A/BSCL2/ARV1/GLIPR1/POR/DGAT2/EDF1/ORMDL2/LDLRAP1/ACACB/PEX11A/FASN/MBTPS2/SPHK2/PIK3R4/OPA3/TNFAIP8L3/TTC39B/PPARD/TAZ/CYP7A1/TGFB1/RDH10/GSTZ1/PDGFB/NCOR1/SREBF2/ORMDL3/NFYB/TRIB3/SIRT1	111
BP	GO:0090174	organelle membrane fusion	29/4749	100/18670	0.2374	0.536	0.436	ANXA2P2/CHMP2B/ANXA2/STX11/STX5/SYT4/SNAP47/SNAP29/STX1B/CORO1A/STX19/SNAP23/TMEM175/STX12/TAP1/VAMP3/STX16/UVRAG/SNAPIN/VTI1B/EEA1/STX2/DOC2B/RAB34/VPS39/VPS8/CHMP3/TRIM9/USO1	29
BP	GO:0003205	cardiac chamber development	48/4749	171/18670	0.2378	0.5367	0.4366	NOTCH1/LUZP1/SRF/PRDM1/MAML1/MYH10/ADAMTS6/DAND5/SMAD7/PTK7/RBPJ/LMO4/SMAD6/DCTN5/JAG1/COL11A1/SALL4/TBX6/PLXND1/GREB1L/MYBPC3/FKBP1A/MDM4/RXRA/XIRP2/ARID1A/MYH7/TAB1/TNNC1/CITED2/SOX11/GSK3A/NPRL3/BMP10/FGF8/TPM1/PCSK5/ADAMTS1/MYH6/TGFB1/POU4F1/RARA/MIR17HG/KCNK2/ZFPM1/DHRS3/GATA3/GJA5	48
BP	GO:0030856	regulation of epithelial cell differentiation	44/4749	156/18670	0.2381	0.5369	0.4368	VDR/LIF/IL1B/CD109/VEGFA/NOTCH1/CBFB/CEACAM1/MMP9/TP63/PTCH1/ASCL1/TNF/ZFP36/PROC/SERPINE1/WNT10B/NUMA1/SFN/SFRP4/WWTR1/SGPP1/PRKX/JAG1/ATOH8/EZH2/CYP27B1/CEBPB/ARNTL/YAP1/GSK3A/IL13/IL20/ADIPOQ/ZFP36L1/STAT1/DLL1/ID1/CCND1/CDH5/TRIM16/GATA3/BAD/NME2	44
BP	GO:0034767	positive regulation of ion transmembrane transport	44/4749	156/18670	0.2381	0.5369	0.4368	WNK1/HSPA2/BAX/CXCL10/TRPC1/COX17/RNF207/CCR2/ATP2A1/AMIGO1/KCNE3/SRI/KCNJ2/PKD2/HTT/CCL2/ATP1B1/KCNMB1/GSTO1/PINK1/CACNG3/STAC3/ACTN4/CXCL9/PIRT/DRD1/STAC/THY1/CD19/SUMO1/NTSR1/CHP1/PARK7/ATP1B3/LACRT/IL13/KCNH2/F2R/TESC/CACNB2/EHD3/GALR2/PTAFR/P2RX7	44
BP	GO:0060021	roof of mouth development	26/4749	89/18670	0.2394	0.5395	0.4389	TWIST1/JAG2/CSRNP1/SKI/ASPH/PLEKHA1/MSX1/SNAI1/ALX1/TGFB3/ARID5B/PRDM16/BCOR/WDPCP/INSIG1/IFT172/SUMO1/WNT7A/ACVR2B/SOX11/NPRL3/DLX5/LRP6/MSC/DHRS3/LRRC32	26
BP	GO:1901019	regulation of calcium ion transmembrane transporter activity	26/4749	89/18670	0.2394	0.5395	0.4389	GEM/HSPA2/YWHAE/JSRP1/MYO5A/REM1/PDE4D/ATP2A1/KCNE3/PDE4B/SRI/PKD2/HTT/GPR35/ATP1B1/GSTO1/REM2/STAC3/FKBP1A/STAC/SUMO1/FMR1/CAMK2D/AHNAK/CACNB2/EHD3	26
BP	GO:0050879	multicellular organismal movement	17/4749	56/18670	0.2401	0.5403	0.4396	C12orf57/ASCL1/JSRP1/MTOR/HOMER1/ATP2A1/KCNJ2/GSTO1/STAC3/STAC/MYH7/CHRNA1/TNNC1/XRCC1/GIGYF2/MAP1A/TCAP	17
BP	GO:0050881	musculoskeletal movement	17/4749	56/18670	0.2401	0.5403	0.4396	C12orf57/ASCL1/JSRP1/MTOR/HOMER1/ATP2A1/KCNJ2/GSTO1/STAC3/STAC/MYH7/CHRNA1/TNNC1/XRCC1/GIGYF2/MAP1A/TCAP	17
BP	GO:0070936	protein K48-linked ubiquitination	17/4749	56/18670	0.2401	0.5403	0.4396	ZNRF1/UBE2C/UBE2A/RFFL/UBE2B/SYVN1/UBE2H/DTX3L/TTC3/KLHL3/UBE2G2/RNF187/TRIM44/RNF8/RNF216/UBE3A/TOPORS	17
BP	GO:0090183	regulation of kidney development	17/4749	56/18670	0.2401	0.5403	0.4396	EGR1/LIF/VEGFA/PDGFA/MMP9/CFLAR/WWTR1/PRKX/HOXB7/SOX8/BASP1/YAP1/ADIPOQ/STAT1/TGFB1/PDGFB/GATA3	17
BP	GO:0008589	regulation of smoothened signaling pathway	23/4749	78/18670	0.2408	0.5415	0.4405	EVC/PDCL/PTCH1/GPR161/GLIS2/FGF9/RUNX2/IFT122/TCTN1/IFT172/MGRN1/WDR11/KCTD21/SCUBE1/CD3E/CTNNA1/BTRC/DLG5/SFRP1/POR/PRKACB/OTX2/RAB34	23
BP	GO:0072347	response to anesthetic	23/4749	78/18670	0.2408	0.5415	0.4405	CCNA2/CDK5/FOSB/HSPA5/MAP1LC3A/PEA15/MTOR/HOMER2/TIAM1/HOMER1/ABAT/EFTUD2/HTR2A/AIF1/DRD1/CNR1/PPP5C/UBE3A/PRKCE/MBD1/PPP1R9B/NPFF/ATG7	23
BP	GO:0019748	secondary metabolic process	20/4749	67/18670	0.2412	0.5418	0.4408	PGAM1/AS3MT/TRPC1/ETHE1/CTNS/MPST/MYO5A/PAM/CTH/N6AMT1/SP1/ASIP/OCA2/BDH2/RAPGEF2/FMO2/CYP2D6/DDT/TYRP1/AKR1A1	20
BP	GO:0043967	histone H4 acetylation	20/4749	67/18670	0.2412	0.5418	0.4408	IRF4/SPI1/BRCA2/SMARCB1/ING3/KANSL3/IWS1/ARRB1/MORF4L2/KANSL1L/KAT2A/ACTL6A/YEATS4/MUC1/MCRS1/KAT6B/CTBP1/TRIM16/KAT6A/SIRT1	20
BP	GO:2000573	positive regulation of DNA biosynthetic process	20/4749	67/18670	0.2412	0.5418	0.4408	AURKB/KLF4/NEK2/PARM1/SRC/RFC2/CCT5/PAK3/DSCC1/TNKS2/ACD/CHTF8/POT1/WRAP53/ATR/ATM/MAPK1/PDGFB/FBXO4/CCT3	20
BP	GO:0007519	skeletal muscle tissue development	45/4749	160/18670	0.2418	0.5418	0.4408	EGR1/TWIST1/EGR2/NOTCH1/HLF/EPHB1/GPC1/CDK5/ATF3/SKI/SVIL/ASB2/GPX1/WNT10B/MYLK2/HOMER1/CFLAR/MYL6/USP19/HLX/ZNF689/CCNT2/MEF2D/STAC3/FLOT1/SOX8/EMD/CHRNA1/DDX17/VGLL2/SOX11/ARNTL/MYL6B/MYOM1/NUPR1/IGSF8/HDAC9/MSC/HMG20B/FOS/POPDC3/DLL1/TAZ/GPCPD1/TGFB1	45
BP	GO:0071901	negative regulation of protein serine/threonine kinase activity	41/4749	145/18670	0.2419	0.5418	0.4408	IL1B/CDKN1A/WNK1/DUSP10/DUSP4/CDKN2B/PTPN6/DUSP6/SPRED2/HEXIM1/DNAJA1/PPP2R1A/PTPN1/PLK1/CDKN2C/PDCD4/SORL1/DUSP5/SFN/IRAK3/DUSP16/PPP2CA/CHORDC1/CDKN2A/GBA/DTNBP1/PRKAG2/DEFB114/DUSP18/SFRP1/ADIPOQ/AIDA/LRP6/STK38/DUSP14/APC/ZNF675/UCHL1/NUP62/SIRT1/DUSP1	41
BP	GO:0009225	nucleotide-sugar metabolic process	12/4749	38/18670	0.242	0.5418	0.4408	MPI/NANS/CSGALNACT1/SLC35D1/GNE/GNPDA1/EXTL2/GSK3A/GUK1/GALT/UAP1L1/NAGK	12
BP	GO:0019068	virion assembly	12/4749	38/18670	0.242	0.5418	0.4408	CHMP2B/SNF8/UBB/RPS27A/TBC1D20/UBA52/CHMP1A/LRSAM1/CHMP2A/RAB1A/CHMP3/RAB1B	12
BP	GO:0046329	negative regulation of JNK cascade	12/4749	38/18670	0.242	0.5418	0.4408	DUSP10/SIRPA/DNAJA1/PDCD4/FKTN/PINK1/CYLD/TAOK3/SFRP1/AIDA/ZNF675/NCOR1	12
BP	GO:0046636	negative regulation of alpha-beta T cell activation	12/4749	38/18670	0.242	0.5418	0.4408	ADORA2A/BCL6/CBFB/TNFSF4/LGALS9/HMGB1/FOXP3/IL4R/SMAD7/HLX/ZC3H12A/JAK3	12
BP	GO:0051693	actin filament capping	12/4749	38/18670	0.242	0.5418	0.4408	CAPZB/GSN/TMOD2/CAPG/ADD3/SPTBN1/TRIOBP/TWF2/SPTAN1/CAPZA1/VILL/ADD2	12
BP	GO:0086091	regulation of heart rate by cardiac conduction	12/4749	38/18670	0.242	0.5418	0.4408	DSC2/YWHAE/SCN1B/KCNE3/KCNJ2/TRPM4/CAMK2D/KCNH2/KCNE4/KCND3/CACNB2/GJA5	12
BP	GO:1901021	positive regulation of calcium ion transmembrane transporter activity	12/4749	38/18670	0.242	0.5418	0.4408	HSPA2/ATP2A1/KCNE3/PKD2/HTT/ATP1B1/GSTO1/STAC3/STAC/SUMO1/CACNB2/EHD3	12
BP	GO:2000279	negative regulation of DNA biosynthetic process	12/4749	38/18670	0.242	0.5418	0.4408	PPARG/SRC/PIF1/TERF1/ACD/CTC1/POT1/ADIPOQ/TINF2/KCNK2/TERF2/DUSP1	12
BP	GO:0007409	axonogenesis	126/4749	468/18670	0.2425	0.5425	0.4414	CRMP1/EGR2/SKIL/VEGFA/NOTCH1/NR4A3/MAP6/NTRK2/CSF1R/SIPA1L1/NTRK1/SRF/RAC1/EPHB1/PLXNB2/CYFIP1/VSTM2L/GPC1/C12orf57/CDK5/SPP1/PTCH1/SEMA4C/PLXNB1/TNFRSF12A/MYH10/SEMA7A/FOXB1/ZSWIM5/CTTN/USP9X/GAB2/ZFYVE27/PITPNA/CNP/SEMA3G/CYFIP2/SRC/EPHB4/NKX2-1/SCN1B/TIAM1/SEMA6C/AMIGO1/NTRK3/PLXNA1/PAK1/MYOT/CCKAR/SEMA6B/EFNB1/ARHGAP35/PDLIM7/CCK/PAK3/LRP4/SPTBN1/FGF13/EZR/PRKCA/STMN1/ARHGAP4/B3GNT2/VASP/S100A6/TWF2/L1CAM/PLXND1/TUBB3/TCTN1/DVL1/ULK1/EXT1/FLOT1/SPTAN1/LRP1/LIMK1/THY1/ZSWIM6/TTL/WNT7A/GDF7/STK25/DOK4/MAP1S/ERBB2/RAC2/PTPRM/NDN/SEMA3B/IST1/BSG/SEMA5B/BRSK2/CHN1/B4GALT5/SLITRK5/DLX5/PTPRS/DOK2/FEZF1/PARD6B/SEMA4D/MAP1A/FGF8/LRRC4C/OTX2/ARHGDIA/NEFL/RAPH1/RUFY3/SEMA5A/POU4F1/RTN4R/UCHL1/ADNP/MAPK1/TRPC5/VAX2/GATA3/GDI1/SHC1/FYN/ILK/SLC9A6/ACTB	126
BP	GO:0014812	muscle cell migration	30/4749	104/18670	0.2428	0.5431	0.4419	NR4A3/ITGA2/TRIB1/PDGFA/PLAU/SERPINE1/SORL1/PLAT/SRC/CORO1B/PLXNA1/PAK1/FGF9/IGFBP3/DOCK5/AIF1/VTN/ARPC5/LRP1/CRK/DDR1/ADIPOQ/TPM1/ADAMTS1/PPARD/THBS4/HAS2/NET1/PDGFB/ILK	30
BP	GO:0008361	regulation of cell size	50/4749	179/18670	0.2446	0.5469	0.4449	IQGAP3/VEGFA/SRF/RAC1/CYFIP1/CDK5/SPP1/SEMA4C/TNFRSF12A/SEMA7A/CTTN/AKT3/MTOR/ZFYVE27/SLC12A4/SEMA3G/SLC12A2/SEMA6C/NTRK3/PAK1/SEMA6B/VAV2/FGF13/ARHGAP4/TWF2/L1CAM/KCNN4/LRP1/LIMK1/TTL/DEPTOR/IL7R/SEMA3B/IST1/SEMA5B/RAP1GAP2/PTPRS/PRR16/LAMTOR4/SEMA4D/SLC12A6/RUFY3/SEMA5A/RTN4R/ADNP/TRPC5/SLC12A5/GDI1/P2RX7/ILK	50
BP	GO:0035821	modification of morphology or physiology of other organism	46/4749	164/18670	0.2454	0.5476	0.4455	CSF1R/GAPDH/CLEC7A/ANXA2P2/TYMS/SMC3/KPNA2/ANXA2/SMARCB1/RPL30/CCL3/NTRK3/LYZ/MPEG1/PGLYRP3/SMARCA4/RPS19/TBC1D20/ROMO1/CFL1/SCRIB/SP1/HMGN2/LCE3C/ARG1/RXRA/JUN/FMR1/KPNA3/TAF11/CCNK/ZNF639/BCL2L1/ZC3H12A/HTN3/APOL1/DEFA1B/KRT6A/INSR/DEFA4/STOM/NUCKS1/ATG7/TGFB1/P2RX7/BAD	46
BP	GO:0009154	purine ribonucleotide catabolic process	10/4749	31/18670	0.2468	0.5476	0.4455	PDE4A/ABCD1/NUDT16/PDE4D/PDE4B/HPRT1/NUDT3/AMPD3/NT5E/PDE7B	10
BP	GO:0021988	olfactory lobe development	10/4749	31/18670	0.2468	0.5476	0.4455	KIF14/CSF1R/SRF/ATF5/SEMA7A/SKI/EXT1/AGTPBP1/DLX5/FEZF1	10
BP	GO:0031572	G2 DNA damage checkpoint	10/4749	31/18670	0.2468	0.5476	0.4455	CDK1/DTL/CLSPN/PLK1/TAOK3/BRCC3/CHEK1/CDC14B/ATM/SYF2	10
BP	GO:0040020	regulation of meiotic nuclear division	10/4749	31/18670	0.2468	0.5476	0.4455	LIF/TTK/TRIP13/CDC20/FBXO43/UBE2B/MSX1/FBXO5/SIRT2/PLCB1	10
BP	GO:0045879	negative regulation of smoothened signaling pathway	10/4749	31/18670	0.2468	0.5476	0.4455	PTCH1/GPR161/GLIS2/RUNX2/IFT122/MGRN1/KCTD21/CD3E/BTRC/PRKACB	10
BP	GO:0045880	positive regulation of smoothened signaling pathway	10/4749	31/18670	0.2468	0.5476	0.4455	EVC/PDCL/FGF9/IFT172/SCUBE1/CTNNA1/DLG5/SFRP1/POR/RAB34	10
BP	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process	10/4749	31/18670	0.2468	0.5476	0.4455	CHST15/CHPF2/B3GAT3/CSGALNACT1/SLC35D1/B3GALT6/CHST7/CHPF/CHST13/XYLT1	10
BP	GO:0050685	positive regulation of mRNA processing	10/4749	31/18670	0.2468	0.5476	0.4455	NUP98/CCNB1/CIRBP/SF3B4/PRPF19/RBMY1B/PRDX6/CPEB1/RBM3/NCBP2	10
BP	GO:0070306	lens fiber cell differentiation	10/4749	31/18670	0.2468	0.5476	0.4455	SKIL/NF2/NTRK3/KDM5B/TBC1D20/WNT7A/MAF/VIM/BFSP2/TGFB1	10
BP	GO:1904707	positive regulation of vascular smooth muscle cell proliferation	15/4749	49/18670	0.2472	0.5476	0.4455	NR4A3/IL10/MMP9/TNF/PAK1/FGF9/MAP3K5/MEF2D/GNAI2/JUN/ERN1/LDLRAP1/HPGD/ADAMTS1/PDGFB	15
BP	GO:0030004	cellular monovalent inorganic cation homeostasis	31/4749	108/18670	0.248	0.5476	0.4455	GRN/ATP6V0D1/TMPRSS3/SLC4A2/ATP6V0B/SLC4A3/ATP6V1E1/PPT1/KCNJ2/ATP6V0C/ATP1B1/SLC9A7/SLC4A11/ATP6V1A/ROGDI/SLC26A6/SLC4A10/TMEM175/CHP1/ATP1B3/CA2/RAB38/SNAPIN/ATP6V1G1/SLC9B1/DMXL1/ATP6V1E2/DMXL2/CCDC115/MAPK1/SLC9A6	31
BP	GO:0000963	mitochondrial RNA processing	6/4749	17/18670	0.2481	0.5476	0.4455	PUS1/TRMT10B/TRIT1/TRMT10C/TBRG4/TRNT1	6
BP	GO:0002693	positive regulation of cellular extravasation	6/4749	17/18670	0.2481	0.5476	0.4455	ICAM1/IL1R1/CCR2/THY1/CD99L2/PTAFR	6
BP	GO:0009070	serine family amino acid biosynthetic process	6/4749	17/18670	0.2481	0.5476	0.4455	SERINC3/GGT1/CTH/MTHFD1/SEPHS1/PSPH	6
BP	GO:0009129	pyrimidine nucleoside monophosphate metabolic process	6/4749	17/18670	0.2481	0.5476	0.4455	TYMS/DHODH/UPRT/DCTD/CMPK1/UCK2	6
BP	GO:0010715	regulation of extracellular matrix disassembly	6/4749	17/18670	0.2481	0.5476	0.4455	FSCN1/CST3/CLASP2/LRP1/DDR1/TGFB1	6
BP	GO:0014733	regulation of skeletal muscle adaptation	6/4749	17/18670	0.2481	0.5476	0.4455	MTOR/GTF2IRD2B/MYH7/CAMK2G/TNNC1/GTF2IRD1	6
BP	GO:0015919	peroxisomal membrane transport	6/4749	17/18670	0.2481	0.5476	0.4455	ABCD1/PEX2/PEX3/PEX5/PEX13/PEX1	6
BP	GO:0017085	response to insecticide	6/4749	17/18670	0.2481	0.5476	0.4455	CPOX/CCNB1/SCN1B/UBA52/ZC3H12A/NEFL	6
BP	GO:0030011	maintenance of cell polarity	6/4749	17/18670	0.2481	0.5476	0.4455	ANK1/ARPC5/WDR1/DLG5/LIN7C/PDZD11	6
BP	GO:0031268	pseudopodium organization	6/4749	17/18670	0.2481	0.5476	0.4455	CDC42EP4/SRGAP2/CDC42EP1/APC/C15orf62/CDC42	6
BP	GO:0031649	heat generation	6/4749	17/18670	0.2481	0.5476	0.4455	IL1B/TNF/ARRDC3/ABAT/CNR1/TNFSF11	6
BP	GO:0035313	wound healing, spreading of epidermal cells	6/4749	17/18670	0.2481	0.5476	0.4455	HBEGF/COL5A1/MTOR/MMP12/CLASP2/WNT7A	6
BP	GO:0035855	megakaryocyte development	6/4749	17/18670	0.2481	0.5476	0.4455	SRF/PTPN6/ZNF385A/PIP4K2A/WASF2/ZFPM1	6
BP	GO:0036149	phosphatidylinositol acyl-chain remodeling	6/4749	17/18670	0.2481	0.5476	0.4455	MBOAT7/PLBD1/PLA2G12A/PLA2G2A/LCLAT1/PLA2G5	6
BP	GO:0042268	regulation of cytolysis	6/4749	17/18670	0.2481	0.5476	0.4455	CSF2/PGLYRP3/CFHR1/KRT6A/TGFB1/P2RX7	6
BP	GO:0042790	nucleolar large rRNA transcription by RNA polymerase I	6/4749	17/18670	0.2481	0.5476	0.4455	MTOR/SMARCB1/SMARCA4/NCL/DDX11/IPPK	6
BP	GO:0042953	lipoprotein transport	6/4749	17/18670	0.2481	0.5476	0.4455	PPARG/UNC119/LRP1/CUBN/PRKCB/UNC119B	6
BP	GO:0044872	lipoprotein localization	6/4749	17/18670	0.2481	0.5476	0.4455	PPARG/UNC119/LRP1/CUBN/PRKCB/UNC119B	6
BP	GO:0050665	hydrogen peroxide biosynthetic process	6/4749	17/18670	0.2481	0.5476	0.4455	CYBB/CTNS/STAT3/ZNF205/CYBA/FYN	6
BP	GO:0060644	mammary gland epithelial cell differentiation	6/4749	17/18670	0.2481	0.5476	0.4455	PTCH1/FOXB1/CEBPB/ZNF703/LBH/MGMT	6
BP	GO:0062033	positive regulation of mitotic sister chromatid segregation	6/4749	17/18670	0.2481	0.5476	0.4455	ESPL1/CDT1/DLGAP5/NUMA1/ANAPC11/SMC5	6
BP	GO:0071850	mitotic cell cycle arrest	6/4749	17/18670	0.2481	0.5476	0.4455	CDKN1A/GADD45A/CDC14B/GADD45GIP1/MCPH1/DUSP1	6
BP	GO:0097329	response to antimetabolite	6/4749	17/18670	0.2481	0.5476	0.4455	TREX1/ASNS/DHFR/TIMELESS/FMR1/DDX11	6
BP	GO:1903975	regulation of glial cell migration	6/4749	17/18670	0.2481	0.5476	0.4455	CSF1/CCR2/TIAM1/CCL3/LRP1/CX3CR1	6
BP	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell	6/4749	17/18670	0.2481	0.5476	0.4455	ICAM1/TNF/CCR2/IRAK1/TRAF6/PTAFR	6
BP	GO:2000811	negative regulation of anoikis	6/4749	17/18670	0.2481	0.5476	0.4455	NOTCH1/NTRK2/MCL1/SRC/CEACAM5/ZNF304	6
BP	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	21/4749	71/18670	0.2488	0.5482	0.446	LIF/IL18/CSF2/IL21/CSF1R/TNFRSF18/CNTF/TNF/STAT3/PARP14/SOCS3/FLT3/PTK6/OSM/PIBF1/IL13/IL20/IL4/ARL2BP/FYN/IL23A	21
BP	GO:0051893	regulation of focal adhesion assembly	18/4749	60/18670	0.249	0.5482	0.446	VEGFA/SDC4/RAC1/CORO1C/SRC/LIMS1/CLASP2/WDPCP/LIMCH1/DUSP22/S100A10/LRP1/THY1/EPB41L5/SFRP1/BCAS3/FMN1/LDB1	18
BP	GO:0090109	regulation of cell-substrate junction assembly	18/4749	60/18670	0.249	0.5482	0.446	VEGFA/SDC4/RAC1/CORO1C/SRC/LIMS1/CLASP2/WDPCP/LIMCH1/DUSP22/S100A10/LRP1/THY1/EPB41L5/SFRP1/BCAS3/FMN1/LDB1	18
BP	GO:0009100	glycoprotein metabolic process	113/4749	419/18670	0.2493	0.5482	0.446	HBEGF/B3GNT5/SULF2/PHLDA1/HS3ST3B1/TREX1/HS3ST3A1/MPDU1/DOLPP1/CHST15/NEU4/CANT1/HPSE/GBGT1/GPC1/GALNT2/GORASP1/MPI/MCFD2/SDF2L1/SERP2/GALNT12/CHPF2/ENTPD5/MGAT4B/ITM2A/MMP12/SYVN1/IDS/B3GAT3/POMT2/CSGALNACT1/IDUA/VCP/CST3/NUDT14/MAN2B1/ENGASE/EOGT/SLC35D1/NECAB3/FKTN/MGAT5B/DPM2/FBXO27/COG7/TCF7L2/GALNT1/B3GALT6/MGAT4A/UBE2G2/ST8SIA1/ACOT8/COL11A1/B3GNT2/ADAMTS13/SPOCK3/CHST7/ST6GALNAC4/TRIM13/EXT1/EXTL2/LMF1/MUC1/TMEM115/CHP1/PARK7/PRKCSH/DSEL/ST3GAL3/HS6ST1/SDF2/SLC35C1/EDEM2/ACER2/MGAT5/POGLUT1/ADAMTS9/ITM2B/CHPF/B4GALT5/GALNT10/COG3/RNF139/SERP1/XXYLT1/GANAB/ITM2C/FUT6/HS3ST4/AGA/HEXB/RAB1A/GAL3ST4/CHST13/PLOD3/MANBA/FBXO44/MAN1A1/ST8SIA3/PORCN/XYLT1/PPARD/DOLK/PLCB1/ALG6/C1GALT1/JAK3/ST6GALNAC6/B4GALT4/MOGS/B4GALT7/RAB1B	113
BP	GO:0009110	vitamin biosynthetic process	8/4749	24/18670	0.2496	0.5482	0.446	VDR/IL1B/TNF/MMAB/SNAI1/CYP27B1/MMACHC/AKR1A1	8
BP	GO:0021544	subpallium development	8/4749	24/18670	0.2496	0.5482	0.446	BBS2/ASCL1/HPRT1/MKKS/DRD1/ZSWIM6/SLITRK5/FGF8	8
BP	GO:0032897	negative regulation of viral transcription	8/4749	24/18670	0.2496	0.5482	0.446	ZFP36/TRIM62/CCL3/TRIM13/IFITM3/MID2/JUN/ZNF639	8
BP	GO:0034629	cellular protein-containing complex localization	8/4749	24/18670	0.2496	0.5482	0.446	TNFAIP2/SMAD7/EZR/KLHL21/SNAPIN/CEP72/RALB/SEH1L	8
BP	GO:0036010	protein localization to endosome	8/4749	24/18670	0.2496	0.5482	0.446	SORL1/DTX3L/MICALL1/TOLLIP/EZR/SCRIB/TMEM30A/ARF6	8
BP	GO:0042104	positive regulation of activated T cell proliferation	8/4749	24/18670	0.2496	0.5482	0.446	IL18/HMGB1/IL2RA/RPS3/IL12RB1/TNFSF9/HHLA2/IL23A	8
BP	GO:0051905	establishment of pigment granule localization	8/4749	24/18670	0.2496	0.5482	0.446	MYO7A/BBS2/MYO5A/BLOC1S6/MKKS/RAB27A/ASIP/RAB1A	8
BP	GO:0060343	trabecula formation	8/4749	24/18670	0.2496	0.5482	0.446	SRF/WNT10B/PPARGC1B/FKBP1A/SFRP1/BMP10/ADAMTS1/SLC40A1	8
BP	GO:1903421	regulation of synaptic vesicle recycling	8/4749	24/18670	0.2496	0.5482	0.446	CYFIP1/CDK5/GRIPAP1/SLC2A4/SH3GL1/STX1B/SYT11/DNM1	8
BP	GO:2000209	regulation of anoikis	8/4749	24/18670	0.2496	0.5482	0.446	NOTCH1/NTRK2/MCL1/SRC/CEACAM5/ZNF304/MYBBP1A/CHEK2	8
BP	GO:0007044	cell-substrate junction assembly	28/4749	97/18670	0.2511	0.5511	0.4484	PLEC/VEGFA/SDC4/ITGA2/RAC1/CORO1C/CTTN/SRC/TRIP6/LIMS1/CLASP2/WDPCP/LIMCH1/ITGA6/DUSP22/S100A10/LRP1/THY1/EPB41L5/CD151/SFRP1/BCR/WHAMM/PIP5K1A/BCAS3/FMN1/LAMA5/LDB1	28
BP	GO:0021543	pallium development	48/4749	172/18670	0.2523	0.5537	0.4504	KIF14/MBOAT7/ASPM/NR4A3/NTRK2/WDR62/SRF/TACC3/CDK5/BBS2/MFSD2A/YWHAE/NF2/ASCL1/LRP8/SRGAP2/BAX/XRN2/NKX2-1/ARHGAP11B/SUN2/EIF2B3/FGF13/EZH2/BCL2A1/MKKS/DRD1/ATP2B4/LRP1/SLC38A2/CRK/XRCC1/HTR6/TMEM14B/HSD3B2/PTPRS/LRP6/FGF8/NEFL/EFHC1/MCPH1/LHX6/PLCB1/PEX13/UBA6/RARA/SYNE2/BAD	48
BP	GO:0017158	regulation of calcium ion-dependent exocytosis	32/4749	112/18670	0.253	0.5548	0.4514	NOTCH1/ADORA2A/RIMS3/CDK5/SYN1/NCS1/CHRNA5/HYAL3/P2RX1/SYT4/HTR2A/CAMK2A/PFN2/APBA2/STX1B/DVL1/DRD1/DTNBP1/GNAI2/WNT7A/CNR1/FMR1/SYT11/SNAPIN/NAPB/DOC2B/PRKCB/P2RY1/CACNB2/FBXL20/SYT15/TRIM9	32
BP	GO:0098693	regulation of synaptic vesicle cycle	32/4749	112/18670	0.253	0.5548	0.4514	ADORA2A/CYFIP1/RIMS3/CDK5/SYN1/NCS1/CHRNA5/GRIPAP1/P2RX1/SYT4/HTR2A/CAMK2A/PFN2/SLC2A4/SH3GL1/APBA2/STX1B/DVL1/DRD1/DTNBP1/WNT7A/CNR1/FMR1/SYT11/BRSK2/SNAPIN/NAPB/DNM1/PRKCB/P2RY1/CACNB2/FBXL20	32
BP	GO:0007160	cell-matrix adhesion	62/4749	225/18670	0.2533	0.5553	0.4518	VEGFA/SDC4/ITGA2/ITGA3/SRF/RAC1/BCL6/ZYX/HPSE/CDK5/CORO1C/NF2/CSF1/CTTN/PLAU/NINJ1/SERPINE1/MMP12/SRC/TIAM1/TRIP6/LIMS1/NID1/JAG1/CLASP2/WDPCP/ITGA1/PLEKHA2/ADAMTS13/L1CAM/LIMCH1/ITGA6/DUSP22/VTN/S100A10/CDKN2A/LRP1/THY1/EPB41L5/CD44/ACER2/STRC/MSLN/MINK1/ADAM15/DDR1/CD3E/ADAMTS9/SFRP1/CD34/ITGA2B/UTRN/BCR/WHAMM/PIP5K1A/BCAS3/ADAM9/FMN1/LAMA5/CD96/LDB1/ILK	62
BP	GO:0007030	Golgi organization	40/4749	142/18670	0.2538	0.556	0.4524	CDK1/CIT/SURF4/PDE4DIP/GORASP1/ATP8B4/YWHAZ/PLEKHM2/STX5/SEC16A/HTT/NPLOC4/COG7/TMED3/TBC1D20/CLASP2/VPS51/PI4K2A/TMED9/COG1/STK25/GBF1/TMED10/TMED5/STX16/LMAN2/ATP8B3/TMED4/RAB2A/COG3/NSFL1C/RAB1A/EHD3/TMED1/BCAS3/CDC42/TMED6/TRAPPC12/MAPK1/USO1	40
BP	GO:1902904	negative regulation of supramolecular fiber organization	40/4749	142/18670	0.2538	0.556	0.4524	CAPZB/GSN/CKAP2/LDLR/MYADM/SWAP70/TMOD2/CAPG/ARHGEF2/CLIP3/CORO1B/CLU/ADD3/PFN2/HIP1R/S1PR1/PICK1/TMSB4Y/SPTBN1/FGF13/CORO1A/STMN1/CLASP2/TRIOBP/TWF2/SPTAN1/MKKS/ARAP1/MID1/CAPZA1/TUBB4A/TRIM54/KANK3/TMSB15A/VILL/APC/WASF2/WAS/CDH5/ADD2	40
BP	GO:0010559	regulation of glycoprotein biosynthetic process	13/4749	42/18670	0.2543	0.5565	0.4527	HBEGF/ITM2A/POMT2/NECAB3/FKTN/TCF7L2/ACOT8/CHP1/ACER2/ITM2B/ITM2C/PLCB1/JAK3	13
BP	GO:0015701	bicarbonate transport	13/4749	42/18670	0.2543	0.5565	0.4527	SLC4A2/SLC4A3/CYB5R2/HBA2/SLC4A11/SLC26A6/SLC4A10/CA2/CYB5R1/HBB/CA4/CYB5RL/CA13	13
BP	GO:0030517	negative regulation of axon extension	13/4749	42/18670	0.2543	0.5565	0.4527	CDK5/SEMA4C/SEMA7A/SEMA3G/SEMA6C/SEMA6B/ARHGAP4/SEMA3B/SEMA5B/PTPRS/SEMA4D/SEMA5A/RTN4R	13
BP	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	13/4749	42/18670	0.2543	0.5565	0.4527	XRN2/USB1/DCPS/ISG20/DIS3L2/ERI3/PAN3/EXOSC2/ANGEL1/ZC3H12A/CNOT7/DIS3L/EXOSC9	13
BP	GO:0032259	methylation	99/4749	366/18670	0.2546	0.5567	0.4529	DOT1L/SPI1/PHF19/PRDM1/AS3MT/TYMS/GAMT/SETD7/SMYD5/SMARCB1/LMNA/TRMT12/DPH5/TDRD9/PRDM8/FAM98B/IWS1/MBD2/GNAS/PRMT7/GTPBP3/SETD6/RAB3D/ALKBH8/NSUN4/PRDM16/HEMK1/TRMT1/BCOR/SATB1/PICK1/GSTO1/CARM1/ZNF304/NSUN5P1/N6AMT1/EED/BRD4/EZH2/SETD4/SUPT6H/BHMT/TARBP1/PRDM15/ASMTL/NSUN6/TRMT10B/TRMT13/MTRR/TRMT112/PCMTD2/METTL8/EMG1/SETD1B/SNRPB/METTL4/TRMT2A/MAPT-AS1/MLLT6/FBL/FDXACB1/RRNAD1/METTL16/GNMT/SETDB2/ZCCHC4/FBXO11/WDR5B/FAM86B2/TDRD5/METTL5/TRMT10C/DMRTC2/SMYD4/ASZ1/METTL25/BAZ2A/MTR/RRP8/GSPT1/WDR82/TRMT1L/AMT/MBD1/ARID4A/CAMKMT/FOS/TFB2M/KDM4C/NSUN2/NDUFAF5/MGMT/SETDB1/GATA3/METTL7B/BHMT2/ZFP57/PIWIL4/SIRT1	99
BP	GO:0046173	polyol biosynthetic process	22/4749	75/18670	0.2559	0.5595	0.4552	PLCD3/DHFR/IMPA2/GBA/PLCL2/NTSR1/ITPKC/CYP27B1/ACER1/PPIP5K1/ACER2/ASAH2/IP6K1/ASAH2B/P2RY1/SPHK2/IP6K2/IPPK/SPR/PLCB1/PTAFR/IP6K3	22
BP	GO:0000186	activation of MAPKK activity	16/4749	53/18670	0.257	0.5608	0.4562	NTRK1/MAP3K6/MAP3K2/MAP3K5/NRK/MAP3K11/TAOK3/RAPGEF1/CRK/MAP3K3/RIPK2/F2R/LAMTOR2/MAP3K9/MAPK1/ADAM9	16
BP	GO:0043331	response to dsRNA	16/4749	53/18670	0.257	0.5608	0.4562	IFIT1/PQBP1/PMAIP1/CARD9/SLC3A2/IRAK3/RFTN1/FLOT1/NFKBIA/IRF3/RIPK2/COLEC12/RALB/ZCCHC3/MAPK1/P2RX7	16
BP	GO:0045851	pH reduction	16/4749	53/18670	0.257	0.5608	0.4562	GRN/ATP6V0D1/ATP6V0B/ATP6V1E1/PPT1/ATP6V0C/ATP6V1A/ROGDI/CA2/RAB38/SNAPIN/ATP6V1G1/DMXL1/ATP6V1E2/DMXL2/CCDC115	16
BP	GO:0060563	neuroepithelial cell differentiation	16/4749	53/18670	0.257	0.5608	0.4562	MYO7A/NOTCH1/JAG2/ASCL1/SERPINE1/RBPJ/FAM20C/JAG1/WDPCP/TRIOBP/SCRIB/CEBPB/STRC/SOX11/FGF8/DLL1	16
BP	GO:0030032	lamellipodium assembly	19/4749	64/18670	0.2572	0.5608	0.4562	FSCN1/ABLIM1/RAC1/CYFIP1/CAPZB/SRGAP2/MTOR/S1PR1/VAV2/TWF2/PARVB/RAC2/FER/ABLIM2/WASF2/WHAMM/CDC42/WAS/SPATA13	19
BP	GO:0043297	apical junction assembly	19/4749	64/18670	0.2572	0.5608	0.4562	SRF/CBFB/TNF/SNAI1/RAB13/MPP7/MPP5/PRKCI/ACTN4/ECT2/WDR1/PARD6G/CTNNA1/DLG5/PARD6B/APC/PARD6A/ARL2/FZD5	19
BP	GO:0045669	positive regulation of osteoblast differentiation	19/4749	64/18670	0.2572	0.5608	0.4562	TP63/WNT10B/CLIC1/FBXO5/CTHRC1/GNAS/FAM20C/RUNX2/PDLIM7/JAG1/ATRAID/IFITM1/ACVR2B/CEBPB/SOX11/SMAD1/SUCO/TMEM119/ILK	19
BP	GO:0048278	vesicle docking	19/4749	64/18670	0.2572	0.5608	0.4562	STX11/STX5/BLOC1S6/CAMK2A/VPS33B/RAB3D/SCFD2/STX1B/STX19/STX12/PPFIA3/VAMP3/STX16/EXOC6B/VTI1B/STX2/RAB15/RALB/USO1	19
BP	GO:0045834	positive regulation of lipid metabolic process	41/4749	146/18670	0.2577	0.5617	0.4569	TWIST1/IL1B/NR4A3/PPARG/ABCG1/TNF/MTOR/LDLR/ABCD1/SRC/ABCD2/DGKZ/HTR2A/CD74/AMBRA1/FLT3/VAV2/SLC45A3/NOD2/CD19/FLT1/FPR2/AGAP2/PRKCE/RAB38/EEF1A2/CREBL2/ADM/ADIPOQ/CPT1A/POR/DGAT2/LDLRAP1/SPHK2/PIK3R4/TNFAIP8L3/TAZ/CYP7A1/TGFB1/RDH10/PDGFB	41
BP	GO:1900180	regulation of protein localization to nucleus	33/4749	116/18670	0.2578	0.5617	0.4569	LIF/GTSE1/CDK1/RBM22/NF2/PLK1/LMNA/SRC/DTX3L/LILRB4/GLIS2/CCT5/BYSL/OTUD7B/NOLC1/CHP1/PARK7/EFCAB7/MCRS1/CABP1/ECT2/ZC3H12A/BAG3/RAB23/CD2AP/EIF2AK3/TGFB1/MAPK1/NUP62/SESN2/FBXO4/FYN/CCT3	33
BP	GO:0016051	carbohydrate biosynthetic process	59/4749	214/18670	0.2581	0.5622	0.4574	B3GNT5/TPI1/GAPDH/MPDU1/CHST15/ENO1/PGAM1/ATF3/GPI/NANS/PPP1CB/SLC25A1/MTOR/SDS/CRTC2/PGM2L1/CSGALNACT1/GYG2/ALDOC/CRY1/KAT2A/ATF4/PER2/FOXO1/MDH2/IMPA2/B3GNT2/EXT1/EXTL2/ENO3/MAEA/PPP1R3E/NTSR1/C1QTNF3/EPM2AIP1/HAS3/GSK3A/PHKG2/B4GALT5/ALDOA/GNMT/ADIPOQ/DGAT2/P2RY1/INSR/CHST13/SLC35B4/ALDOB/PGD/TGFB1/CLK2/HAS2/ST6GALNAC6/PDGFB/SESN2/AKR1A1/PTAFR/PPP1R3B/SIRT1	59
BP	GO:0014033	neural crest cell differentiation	26/4749	90/18670	0.2597	0.5654	0.46	TWIST1/CORO1C/SEMA4C/SEMA7A/SEMA3G/ALX1/SEMA6C/SEMA6B/EFNB1/CYP26C1/JAG1/FAM172A/CFL1/NOLC1/SOX8/SOX11/SEMA3B/SEMA5B/SFRP1/LRP6/SEMA4D/SEMA5A/MAPK1/RDH10/PEF1/LAMA5	26
BP	GO:0045132	meiotic chromosome segregation	26/4749	90/18670	0.2597	0.5654	0.46	ESPL1/BUB1B/TTK/TOP2A/TRIP13/PTTG1/BUB1/PPP2R1A/SYCE3/NUF2/UBE2B/PLK1/DMC1/CCNE2/TERF1/HELQ/NCAPH/REC8/STAG3/EME1/SYCE2/NCAPH2/ANKRD31/ATM/MLH3/RNF212	26
BP	GO:0051294	establishment of spindle orientation	11/4749	35/18670	0.2613	0.5683	0.4623	SAPCD2/CENPA/GPSM2/PLK1/NUMA1/NDC80/ARHGEF2/HTT/ACTR1A/NSFL1C/MCPH1	11
BP	GO:0060338	regulation of type I interferon-mediated signaling pathway	11/4749	35/18670	0.2613	0.5683	0.4623	IRF7/PTPN6/TREX1/PTPN1/MMP12/ABCE1/SCRIB/IRF3/SAMHD1/CNOT7/YTHDF3	11
BP	GO:1901605	alpha-amino acid metabolic process	61/4749	222/18670	0.2636	0.573	0.4662	BCAT1/P4HA2/IL4I1/SLC6A8/SERINC3/GAMT/DDAH2/SDS/MPST/CARNS1/TST/PFAS/GGT1/SMS/GLS2/ATCAY/GLDC/OGDH/AMDHD1/MTHFS/SARDH/HMGCL/GPT/ASNS/CTH/GCAT/MRI1/DLST/MTHFD1/BHMT/ATP2B4/ARG1/NAGS/PARK7/SEPHS1/CKB/MTRR/MTAP/IDO1/PSPH/GLUD1/FAH/GNMT/P4HTM/ENOPH1/GCLC/HGD/AASDHPPT/HIBADH/CTPS2/MTR/GPT2/ALDH7A1/AMT/PLOD3/ALDH5A1/NIT2/GSTZ1/ADHFE1/ASNSD1/BHMT2	61
BP	GO:0048660	regulation of smooth muscle cell proliferation	47/4749	169/18670	0.2638	0.573	0.4662	HBEGF/IL18/CDKN1A/NR4A3/PPARG/ITGA2/IL10/TRIB1/KLF4/MMP9/TNF/MTOR/PDCD4/HMOX1/TGM2/OGN/TGFB3/PAK1/FGF9/XRCC6/IGFBP3/S1PR1/TCF7L2/MAP3K5/NAMPT/MEF2D/AIF1/IRAK1/NDRG2/GNAI2/JUN/RBPMS2/CYBA/IL13/ADIPOQ/ERN1/LDLRAP1/MNAT1/TRAF6/TPM1/STAT1/HPGD/ADAMTS1/PPARD/PDGFB/PTAFR/ILK	47
BP	GO:0050728	negative regulation of inflammatory response	47/4749	169/18670	0.2638	0.573	0.4662	PBK/TYRO3/PPARG/NLRP3/DUSP10/ADORA2A/IL10/ACP5/KLF4/GRN/PTGIS/SIRPA/IL2RA/CD200/PROC/FOXP3/LDLR/GPX1/ABCD1/IL1R2/PDCD4/SOCS3/ABCD2/PTGER4/C5orf30/PTPRC/RPS19/GBA/C1QTNF3/FPR2/NLRC3/ZC3H12A/RABGEF1/MMP26/GHRL/CHID1/ADIPOQ/IL4/TNFRSF1B/NT5E/PSMB4/SIGLEC10/BCR/PPARD/METRNL/CDH5/GATA3	47
BP	GO:0055067	monovalent inorganic cation homeostasis	43/4749	154/18670	0.2652	0.573	0.4662	ADORA2A/GRN/ATP6V0D1/TMPRSS3/SLC4A2/ATP6V0B/SLC12A4/SLC12A2/SLC4A3/ATP6V1E1/PPT1/KCNJ2/RHCG/ATP6V0C/ATP1B1/SLC9A7/SLC4A11/ATP6V1A/ROGDI/SLC26A6/SLC4A10/TMEM175/GNAI2/CHP1/TFAP2B/ATP1B3/CA2/RAB38/MLLT6/SNAPIN/ATP6V1G1/CYP4F12/KCNH2/SLC9B1/DMXL1/SLC12A6/ATP6V1E2/DMXL2/CCDC115/MAPK1/SLC12A5/MC3R/SLC9A6	43
BP	GO:0010883	regulation of lipid storage	14/4749	46/18670	0.2654	0.573	0.4662	PPARG/ABCG1/TNF/FITM2/FITM1/ABCA1/MEST/NFKBIA/ZC3H12A/ACACB/TTC39B/PPARD/SREBF2/SIRT1	14
BP	GO:0030810	positive regulation of nucleotide biosynthetic process	14/4749	46/18670	0.2654	0.573	0.4662	PFKFB3/ENO1/ENTPD5/STAT3/VCP/HTR2A/PFKFB4/GUCA1C/PINK1/PFKFB2/IL4/INSR/TAZ/P2RX7	14
BP	GO:0032480	negative regulation of type I interferon production	14/4749	46/18670	0.2654	0.573	0.4662	RELB/IL10/ISG15/SIRPA/TRIM25/TRAIP/HAVCR2/UBA7/NPLOC4/CYLD/RNF216/NLRC3/IRF3/PTPRS	14
BP	GO:0035088	establishment or maintenance of apical/basal cell polarity	14/4749	46/18670	0.2654	0.573	0.4662	FSCN1/ANK1/PTK7/SYNJ2BP/PRKCI/SCRIB/WDR1/CLIC4/ARF4/DLG5/LIN7C/CDC42/PDZD11/ILK	14
BP	GO:0043277	apoptotic cell clearance	14/4749	46/18670	0.2654	0.573	0.4662	TYRO3/TREX1/HMGB1/FCN1/MERTK/TGM2/TXNDC5/AXL/CCL2/CD300LF/LRP1/TYROBP/RARA/RAC3	14
BP	GO:0043330	response to exogenous dsRNA	14/4749	46/18670	0.2654	0.573	0.4662	IFIT1/PQBP1/CARD9/SLC3A2/IRAK3/RFTN1/FLOT1/NFKBIA/IRF3/RIPK2/COLEC12/RALB/ZCCHC3/MAPK1	14
BP	GO:0048599	oocyte development	14/4749	46/18670	0.2654	0.573	0.4662	AURKA/TRIP13/PPP2R1A/BRCA2/CCNB1/FBXO5/PABPC1L/DMC1/FIGLA/REC8/SIRT2/TDRD5/ATM/CDC25B	14
BP	GO:0061245	establishment or maintenance of bipolar cell polarity	14/4749	46/18670	0.2654	0.573	0.4662	FSCN1/ANK1/PTK7/SYNJ2BP/PRKCI/SCRIB/WDR1/CLIC4/ARF4/DLG5/LIN7C/CDC42/PDZD11/ILK	14
BP	GO:1900373	positive regulation of purine nucleotide biosynthetic process	14/4749	46/18670	0.2654	0.573	0.4662	PFKFB3/ENO1/ENTPD5/STAT3/VCP/HTR2A/PFKFB4/GUCA1C/PINK1/PFKFB2/IL4/INSR/TAZ/P2RX7	14
BP	GO:1904036	negative regulation of epithelial cell apoptotic process	14/4749	46/18670	0.2654	0.573	0.4662	ICAM1/SERPINE1/MTOR/HMOX1/CFLAR/PAK4/TCF7L2/IL13/IL4/KRIT1/NUPR1/SEMA5A/GATA3/PDX1	14
BP	GO:0006906	vesicle fusion	27/4749	94/18670	0.2655	0.573	0.4662	ANXA2P2/ANXA2/STX11/STX5/SYT4/SNAP47/SNAP29/STX1B/CORO1A/STX19/SNAP23/TMEM175/STX12/TAP1/VAMP3/STX16/UVRAG/SNAPIN/VTI1B/EEA1/STX2/DOC2B/RAB34/VPS39/VPS8/TRIM9/USO1	27
BP	GO:0042158	lipoprotein biosynthetic process	27/4749	94/18670	0.2655	0.573	0.4662	ZDHHC12/CLIP3/PIGK/PIGH/DPM2/NMT1/ABCA1/PIGQ/ZDHHC24/PIGO/GBA/ZDHHC3/PIGC/PIGW/PIK3C3/ZDHHC4/ZDHHC9/WDR45/ZDHHC2/ZDHHC7/PIGM/PIGA/PORCN/ZDHHC16/ATG7/PIGG/PIGT	27
BP	GO:0044728	DNA methylation or demethylation	27/4749	94/18670	0.2655	0.573	0.4662	SPI1/APOBEC3H/USP9X/APOBEC3B/ALKBH2/TDRD9/MBD2/GNAS/PRMT7/HEMK1/PICK1/N6AMT1/EZH2/AICDA/MTRR/METTL4/MAPT-AS1/TDRD5/ASZ1/BAZ2A/MBD1/FOS/MGMT/GATA3/ALKBH3/ZFP57/PIWIL4	27
BP	GO:0019751	polyol metabolic process	35/4749	124/18670	0.2668	0.573	0.4662	TPI1/GK/PLCD3/PLD4/SLC5A3/INPP4A/MYOF/SGPP1/DHFR/IMPA2/GALK1/GBA/PLCL2/NTSR1/ITPKC/CYP27B1/ACER1/PPIP5K1/INPP1/ACER2/ASAH2/NUDT3/MOGAT1/IP6K1/DGAT2/ASAH2B/P2RY1/SPHK2/IP6K2/IPPK/SPR/PLCB1/GALR2/PTAFR/IP6K3	35
BP	GO:0048284	organelle fusion	35/4749	124/18670	0.2668	0.573	0.4662	CDK1/ANXA2P2/CHMP2B/BAX/ANXA2/GDAP1/STX11/STX5/SYT4/SNAP47/SNAP29/CYP26C1/STX1B/CORO1A/STX19/BAK1/SNAP23/TMEM175/STX12/TAP1/VAMP3/STX16/UVRAG/SNAPIN/VTI1B/EEA1/STX2/DOC2B/RAB34/VPS39/VPS8/OMA1/CHMP3/TRIM9/USO1	35
BP	GO:0007205	protein kinase C-activating G protein-coupled receptor signaling pathway	9/4749	28/18670	0.2675	0.573	0.4662	ADORA2A/DGKD/HCRT/DGKZ/CCK/PICK1/PRKD3/LRP1/F2R	9
BP	GO:0010818	T cell chemotaxis	9/4749	28/18670	0.2675	0.573	0.4662	CXCL13/WNK1/CXCL10/CCR2/SLC12A2/CCL3/CXCL16/DEFA1B/CCL27	9
BP	GO:0031440	regulation of mRNA 3'-end processing	9/4749	28/18670	0.2675	0.573	0.4662	CCNB1/ZC3H3/RNF40/ZFP36L1/CPEB1/CPSF6/PAPOLA/NCBP2/BARD1	9
BP	GO:0032196	transposition	9/4749	28/18670	0.2675	0.573	0.4662	TREX1/APOBEC3H/APOBEC3B/TDRD9/AICDA/ZNF93/ZNF91/UBR2/PIWIL4	9
BP	GO:0036296	response to increased oxygen levels	9/4749	28/18670	0.2675	0.573	0.4662	CDKN1A/PPARG/ATP6V0D1/FOXO1/FAS/ATP6V1A/ATP6V1G1/ATG7/CCDC115	9
BP	GO:0051123	RNA polymerase II preinitiation complex assembly	9/4749	28/18670	0.2675	0.573	0.4662	THRA/HMGB1/WNT10B/TAF6L/TAF11/TAF7/ESR1/TAF6/PSMC5	9
BP	GO:0052312	modulation of transcription in other organism involved in symbiotic interaction	9/4749	28/18670	0.2675	0.573	0.4662	SMARCB1/CCL3/NTRK3/SMARCA4/SP1/JUN/TAF11/ZNF639/NUCKS1	9
BP	GO:0060122	inner ear receptor cell stereocilium organization	9/4749	28/18670	0.2675	0.573	0.4662	MYO7A/SDC4/CDH23/CTHRC1/TRIOBP/USH1G/SCRIB/IFT27/STRC	9
BP	GO:0070861	regulation of protein exit from endoplasmic reticulum	9/4749	28/18670	0.2675	0.573	0.4662	SORL1/SEC16A/UBE2G2/BCAP31/INSIG1/TMEM30A/EDEM2/BRSK2/UBAC2	9
BP	GO:1902003	regulation of amyloid-beta formation	9/4749	28/18670	0.2675	0.573	0.4662	ABCG1/TNF/SORL1/CLU/SPON1/TMED10/GSK3A/IFNGR1/PRNP	9
BP	GO:1902668	negative regulation of axon guidance	9/4749	28/18670	0.2675	0.573	0.4662	SEMA4C/SEMA7A/SEMA3G/SEMA6C/SEMA6B/SEMA3B/SEMA5B/SEMA4D/SEMA5A	9
BP	GO:0045913	positive regulation of carbohydrate metabolic process	24/4749	83/18670	0.269	0.573	0.4662	PFKFB3/ENTPD5/PMAIP1/SRC/HTR2A/PFKFB4/KAT2A/FOXO1/PFKFB2/SLC45A3/PPP1R3E/NTSR1/EPM2AIP1/PRKCE/PHKG2/DGAT2/P2RY1/INSR/HAS2/PDGFB/PTAFR/P2RX7/BAD/SIRT1	24
BP	GO:0060491	regulation of cell projection assembly	49/4749	177/18670	0.2704	0.573	0.4662	CDC42EP4/ANLN/FSCN1/ICAM1/SRF/RAC1/CYFIP1/CORO1C/KCTD17/CAPZB/CENPJ/MTOR/CDC42EP1/SRC/TENM1/RHOG/ATMIN/TGFB3/SH3YL1/FAM110C/PFN2/HTT/ARHGAP35/EPS8L2/CYLD/WDPCP/TWF2/CDK10/ZMYND10/ARAP1/RALA/PLEKHM1/PPP1R16B/FMR1/MARK4/RAC2/WRAP73/FER/ARF6/APC/WASF2/BCAS3/C15orf62/CDC42/WAS/CEP97/SYNE2/USP17L2/P2RX7	49
BP	GO:0006885	regulation of pH	28/4749	98/18670	0.2709	0.573	0.4662	GRN/ATP6V0D1/SLC4A2/ATP6V0B/SLC4A3/ATP6V1E1/PPT1/RHCG/ATP6V0C/SLC9A7/SLC4A11/ATP6V1A/ROGDI/SLC26A6/SLC4A10/TMEM175/CHP1/CA2/RAB38/SNAPIN/ATP6V1G1/SLC9B1/DMXL1/ATP6V1E2/DMXL2/CCDC115/MAPK1/SLC9A6	28
BP	GO:0050764	regulation of phagocytosis	28/4749	98/18670	0.2709	0.573	0.4662	IL1B/RAB31/PPARG/ITGA2/HCK/SIRPA/CLEC7A/HMGB1/TNF/IL2RB/MERTK/IL2RG/CCL2/IL15RA/PTPRC/CD300LF/CD47/TLR2/LRP1/RAB27A/RAPGEF1/FPR2/SYT11/CYBA/LMAN2/ADIPOQ/BCR/TGFB1	28
BP	GO:0001771	immunological synapse formation	5/4749	14/18670	0.2713	0.573	0.4662	EPHB1/LGALS3/DOCK8/HAVCR2/CD6	5
BP	GO:0003188	heart valve formation	5/4749	14/18670	0.2713	0.573	0.4662	TWIST1/NOTCH1/DCHS1/ZFPM1/GJA5	5
BP	GO:0009214	cyclic nucleotide catabolic process	5/4749	14/18670	0.2713	0.573	0.4662	PDE4A/CNP/PDE4D/PDE4B/PDE7B	5
BP	GO:0010755	regulation of plasminogen activation	5/4749	14/18670	0.2713	0.573	0.4662	ENO1/ANXA2P2/SERPINE1/ANXA2/CTSZ	5
BP	GO:0014819	regulation of skeletal muscle contraction	5/4749	14/18670	0.2713	0.573	0.4662	C12orf57/ATP2A1/KCNJ2/GSTO1/MYH7	5
BP	GO:0019081	viral translation	5/4749	14/18670	0.2713	0.573	0.4662	PTBP1/EIF3L/EIF2D/EIF3G/DENR	5
BP	GO:0030213	hyaluronan biosynthetic process	5/4749	14/18670	0.2713	0.573	0.4662	IL1B/HAS3/TGFB1/HAS2/PDGFB	5
BP	GO:0031272	regulation of pseudopodium assembly	5/4749	14/18670	0.2713	0.573	0.4662	CDC42EP4/CDC42EP1/APC/C15orf62/CDC42	5
BP	GO:0032688	negative regulation of interferon-beta production	5/4749	14/18670	0.2713	0.573	0.4662	RELB/SIRPA/TRAIP/NLRC3/PTPRS	5
BP	GO:0032802	low-density lipoprotein particle receptor catabolic process	5/4749	14/18670	0.2713	0.573	0.4662	FURIN/ANXA2P2/ANXA2/MYLIP/AP2S1	5
BP	GO:0034331	cell junction maintenance	5/4749	14/18670	0.2713	0.573	0.4662	CSF1R/CD177/PLEKHA7/F2R/PARD6A	5
BP	GO:0042487	regulation of odontogenesis of dentin-containing tooth	5/4749	14/18670	0.2713	0.573	0.4662	CSF1/RUNX2/AMTN/TNFRSF11B/FGF8	5
BP	GO:0043173	nucleotide salvage	5/4749	14/18670	0.2713	0.573	0.4662	HPRT1/AMPD2/APRT/AMPD3/UCK2	5
BP	GO:0043455	regulation of secondary metabolic process	5/4749	14/18670	0.2713	0.573	0.4662	PGAM1/SP1/ASIP/RAPGEF2/TYRP1	5
BP	GO:0045346	regulation of MHC class II biosynthetic process	5/4749	14/18670	0.2713	0.573	0.4662	IL10/SPI1/TLR4/IL4/SIRT1	5
BP	GO:0045651	positive regulation of macrophage differentiation	5/4749	14/18670	0.2713	0.573	0.4662	LIF/TRIB1/CSF1/PRKCA/TGFB1	5
BP	GO:0046341	CDP-diacylglycerol metabolic process	5/4749	14/18670	0.2713	0.573	0.4662	AGPAT3/AGPAT2/TAMM41/LCLAT1/GPAT2	5
BP	GO:0046629	gamma-delta T cell activation	5/4749	14/18670	0.2713	0.573	0.4662	EGR3/JAG2/PTPRC/MICA/NOD2	5
BP	GO:0048266	behavioral response to pain	5/4749	14/18670	0.2713	0.573	0.4662	NTRK1/TSPO/SCN9A/PIRT/THBS4	5
BP	GO:0050667	homocysteine metabolic process	5/4749	14/18670	0.2713	0.573	0.4662	MPST/TST/CTH/BHMT/MTRR	5
BP	GO:0051712	positive regulation of killing of cells of other organism	5/4749	14/18670	0.2713	0.573	0.4662	GAPDH/CLEC7A/PGLYRP3/ARG1/BAD	5
BP	GO:0055064	chloride ion homeostasis	5/4749	14/18670	0.2713	0.573	0.4662	SLC12A4/SLC12A2/CKB/SLC12A6/SLC12A5	5
BP	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning	5/4749	14/18670	0.2713	0.573	0.4662	PTCH1/GPR161/IFT122/WDR19/PRKACB	5
BP	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade	5/4749	14/18670	0.2713	0.573	0.4662	MTOR/HOMER2/ATP2B4/CHP1/PRNP	5
BP	GO:0072567	chemokine (C-X-C motif) ligand 2 production	5/4749	14/18670	0.2713	0.573	0.4662	KLF4/TIRAP/TNF/CD74/LRP1	5
BP	GO:0090069	regulation of ribosome biogenesis	5/4749	14/18670	0.2713	0.573	0.4662	USP36/NUDT16/RIOK1/TRMT112/MALSU1	5
BP	GO:0090110	cargo loading into COPII-coated vesicle	5/4749	14/18670	0.2713	0.573	0.4662	SEC13/SEC24D/TBC1D20/INSIG1/RAB1A	5
BP	GO:0097154	GABAergic neuron differentiation	5/4749	14/18670	0.2713	0.573	0.4662	ASCL1/NKX2-1/DRD1/LHX6/RAC3	5
BP	GO:0106057	negative regulation of calcineurin-mediated signaling	5/4749	14/18670	0.2713	0.573	0.4662	MTOR/HOMER2/ATP2B4/CHP1/PRNP	5
BP	GO:0106070	regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	5/4749	14/18670	0.2713	0.573	0.4662	ARRDC3/PRKCA/ATP2B4/GNAI2/GSK3A	5
BP	GO:1901386	negative regulation of voltage-gated calcium channel activity	5/4749	14/18670	0.2713	0.573	0.4662	GEM/REM1/GPR35/REM2/FMR1	5
BP	GO:1903054	negative regulation of extracellular matrix organization	5/4749	14/18670	0.2713	0.573	0.4662	NOTCH1/ADTRP/CST3/TNFRSF1B/TGFB1	5
BP	GO:1903351	cellular response to dopamine	5/4749	14/18670	0.2713	0.573	0.4662	ATF4/DRD1/GABPA/ID1/MAPK1	5
BP	GO:1904152	regulation of retrograde protein transport, ER to cytosol	5/4749	14/18670	0.2713	0.573	0.4662	UBE2G2/BCAP31/EDEM2/BRSK2/UBAC2	5
BP	GO:1904263	positive regulation of TORC1 signaling	5/4749	14/18670	0.2713	0.573	0.4662	SEC13/SIK3/KLHL22/RRAGB/SEH1L	5
BP	GO:1904814	regulation of protein localization to chromosome, telomeric region	5/4749	14/18670	0.2713	0.573	0.4662	CCT5/TERF1/GNL3/WRAP53/CCT3	5
BP	GO:1905049	negative regulation of metallopeptidase activity	5/4749	14/18670	0.2713	0.573	0.4662	TIMP2/SORL1/TIMP1/RECK/TIMP3	5
BP	GO:2001212	regulation of vasculogenesis	5/4749	14/18670	0.2713	0.573	0.4662	CEACAM1/RAPGEF2/ADM/CD34/HIF1AN	5
BP	GO:0046620	regulation of organ growth	32/4749	113/18670	0.2715	0.573	0.4662	MAPK11/NOTCH1/TP73/CDK1/DUSP6/MTOR/PIM1/FXN/CCNB1/PARP2/PAK1/FGF9/RBPJ/HLX/CARM1/STK3/WWC2/CACNA2D2/BASP1/YAP1/IL7/GSK3A/POR/SERP1/ACACB/BMP10/FGF8/RAG2/MYH6/MAPK1/MIR17HG/KCNK2	32
BP	GO:0010810	regulation of cell-substrate adhesion	59/4749	215/18670	0.2715	0.573	0.4662	VEGFA/NOTCH1/SDC4/ITGA3/NEDD9/RAC1/BCL6/CORO1C/NF2/CSF1/PLAU/NINJ1/SERPINE1/MYADM/MMP12/SRC/DOCK1/LIMS1/NID1/DOCK5/LGALS1/EMILIN2/JAG1/PREX1/CLASP2/WDPCP/TRIOBP/PLEKHA2/LIMCH1/ITGA6/ACTN4/DUSP22/VTN/S100A10/CDKN2A/LRP1/THY1/UNC13D/EPB41L5/CRK/PRKCE/RAC2/ACER2/MINK1/ADAM15/DDR1/CD3E/SFRP1/UTRN/C1QBP/ARL2/AP1AR/BCAS3/CDC42/HAS2/FMN1/LDB1/ILK/RAC3	59
BP	GO:0070374	positive regulation of ERK1 and ERK2 cascade	59/4749	215/18670	0.2715	0.573	0.4662	NOTCH1/ICAM1/CSF1R/CCL20/NTRK1/PDGFA/CCL3L3/CCL22/TIRAP/CCR1/GPNMB/LGALS9/HMGB1/TNF/SEMA7A/TLR4/SRC/CFLAR/SCIMP/ARRB1/HTR2A/CCL3/HAVCR2/CD74/FLT3/CCL2/CCL17/CASR/PTPRC/PRKCA/CCL18/NOD2/LRP1/IL26/FLT1/GNAI2/RAPGEF1/FPR2/JUN/CD44/FLT4/RAPGEF2/BRAF/GLIPR2/PLA2G2A/RIPK2/F2R/P2RY1/CCL23/FGF8/TNFAIP8L3/TNFSF11/CCL7/PLA2G5/DDT/TGFB1/CCL15/PDGFB/SHC1	59
BP	GO:0050768	negative regulation of neurogenesis	80/4749	295/18670	0.2716	0.573	0.4662	CRMP1/IL1B/NOTCH1/ASPM/TP73/DUSP10/BCL11A/CNTF/YWHAH/CDK5/SPP1/GORASP1/SEMA4C/ASCL1/TNF/SEMA7A/SRGAP2/PLK2/SKI/RGMA/LDLR/STAT3/SEMA3G/TSPO/SORL1/ARHGEF2/SYT4/SEMA6C/NTRK3/ADCY6/MYLIP/SEMA6B/PTPN9/LGALS1/CBFA2T2/JAG1/STX1B/LRP4/CARM1/FGF13/TBX6/ARHGAP4/LRP1/THY1/WNT7A/SOX8/ZHX2/UBE3A/CTSZ/HMG20A/DTX1/SOX11/SEMA3B/VIM/SEMA5B/PMP22/CTNNA1/GSK3A/RAPGEF2/SNAPIN/SIRT2/RAP1GAP2/PTPRS/ITM2C/DICER1/SEMA4D/ARF6/ARHGDIA/MBD1/PBX1/DLL1/NKX6-2/ID1/RUFY3/TGFB1/SEMA5A/RTN4R/TRPC5/GDI1/TLX3	80
BP	GO:0006631	fatty acid metabolic process	103/4749	383/18670	0.2716	0.573	0.4662	TWIST1/IL1B/NR4A3/PPARG/PDPR/TREX1/PTGIS/ALOX5AP/CYP2S1/CEACAM1/ACSM3/ACOT11/ABHD16A/FADS3/MTOR/ADTRP/TECR/GPX1/ABCD1/THEM5/PON2/MYO5A/MECR/SCD/FA2H/ABCD2/GGT1/PAM/AIG1/FABP5/SLC27A2/MORC2/MCAT/CD74/PER2/EPHX2/ACSL1/GLYATL2/ACOX2/TYSND1/TECRL/PRKAB2/HSD17B8/ACOT8/LIAS/ADIPOR2/ALOX5/SLC45A3/INSIG1/ZADH2/ADIPOR1/PRKAG2/GPX4/CNR1/TBXAS1/AMACR/ELOVL7/ETFA/PEX2/PIBF1/PTGES2/CYP2C18/ELOVL1/BDH2/PLA2G15/ACSL4/ASAH2/ABHD1/CYP4F12/ADIPOQ/CPT1A/OXSM/POR/DGAT2/ASAH2B/SLC27A4/ACACB/ETFB/ACSS1/FASN/PCCB/ACAD11/CYP2D6/ECI1/HPGD/CYP2U1/NUDT19/PECR/PPARD/CYP4V2/CYP7A1/PEX13/TYRP1/ALDH5A1/GPAT2/HADHB/ACOT6/GSTZ1/SESN2/LPIN1/DECR2/TRIB3/SIRT1	103
BP	GO:0000966	RNA 5'-end processing	7/4749	21/18670	0.2719	0.573	0.4662	POP5/NOP14/UTP20/ABT1/TRMT10C/RPP30/THG1L	7
BP	GO:0001779	natural killer cell differentiation	7/4749	21/18670	0.2719	0.573	0.4662	TYRO3/PRDM1/TOX/MERTK/AXL/PGLYRP3/PTPRC	7
BP	GO:0001956	positive regulation of neurotransmitter secretion	7/4749	21/18670	0.2719	0.573	0.4662	ADORA2A/CDK5/STX1B/DTNBP1/CNR1/TACR2/CACNB2	7
BP	GO:0006144	purine nucleobase metabolic process	7/4749	21/18670	0.2719	0.573	0.4662	MTHFD1L/ACPP/HPRT1/MTHFD1/DPYD/APRT/PRPS1	7
BP	GO:0006907	pinocytosis	7/4749	21/18670	0.2719	0.573	0.4662	AXL/PPT1/STX1B/ACTN4/SNX33/MAPKAPK2/EHD4	7
BP	GO:0017000	antibiotic biosynthetic process	7/4749	21/18670	0.2719	0.573	0.4662	CYBB/CTNS/STAT3/ZNF205/CYBA/ACSS1/FYN	7
BP	GO:0021697	cerebellar cortex formation	7/4749	21/18670	0.2719	0.573	0.4662	FAIM2/CDK5/CEND1/WNT7A/AGTPBP1/DLL1/LDB1	7
BP	GO:0032516	positive regulation of phosphoprotein phosphatase activity	7/4749	21/18670	0.2719	0.573	0.4662	MTOR/CD33/PTPRC/ITGA1/PPP1R15A/SLC39A10/PPP1R12A	7
BP	GO:0032674	regulation of interleukin-5 production	7/4749	21/18670	0.2719	0.573	0.4662	NLRP3/TNFRSF21/FOXP3/PDE4D/IL5RA/RARA/GATA3	7
BP	GO:0036344	platelet morphogenesis	7/4749	21/18670	0.2719	0.573	0.4662	CASP9/SRF/PTPN6/ZNF385A/WDR1/MYH9/ZFPM1	7
BP	GO:0042402	cellular biogenic amine catabolic process	7/4749	21/18670	0.2719	0.573	0.4662	SMOX/SARDH/SAT1/BHMT/IDO1/ALDH7A1/SLC44A1	7
BP	GO:0048026	positive regulation of mRNA splicing, via spliceosome	7/4749	21/18670	0.2719	0.573	0.4662	NUP98/CIRBP/SF3B4/PRPF19/RBMY1B/PRDX6/RBM3	7
BP	GO:0071498	cellular response to fluid shear stress	7/4749	21/18670	0.2719	0.573	0.4662	KLF2/KLF4/SRC/PKD2/CA2/HAS2/SREBF2	7
BP	GO:0090280	positive regulation of calcium ion import	7/4749	21/18670	0.2719	0.573	0.4662	LGALS3/ATP2A1/CCL3/CCL2/CASR/SPHK2/PDGFB	7
BP	GO:1902884	positive regulation of response to oxidative stress	7/4749	21/18670	0.2719	0.573	0.4662	MCL1/SFPQ/TNF/TLR4/ACOX2/TLR6/PARK7	7
BP	GO:1903392	negative regulation of adherens junction organization	7/4749	21/18670	0.2719	0.573	0.4662	VEGFA/CORO1C/SRC/CLASP2/DUSP22/LRP1/BCAS3	7
BP	GO:2000316	regulation of T-helper 17 type immune response	7/4749	21/18670	0.2719	0.573	0.4662	NLRP3/FOXP3/SMAD7/IL12RB1/IL27RA/ZC3H12A/IL23A	7
BP	GO:2000737	negative regulation of stem cell differentiation	7/4749	21/18670	0.2719	0.573	0.4662	NOTCH1/STAT3/HSPA9/ZFP36L2/JAG1/YAP1/LBH	7
BP	GO:0000723	telomere maintenance	45/4749	162/18670	0.2723	0.5736	0.4667	AURKB/EXO1/NEK2/PML/SIRT6/BRCA2/SMG5/FEN1/RAD51/SRC/PIF1/XRCC6/CCNE2/UPF1/RFC2/CCT5/NOP10/TERF1/TFIP11/POLD4/TNKS2/ACD/CTC1/GNL3/POLE/RECQL4/POT1/XRCC3/XRCC1/WRAP53/YLPM1/DNA2/SMG6/ATR/TINF2/ATM/WRN/SMC5/MAPK1/ERCC1/FBXO4/ZBTB48/POLE2/TERF2/CCT3	45
BP	GO:0030258	lipid modification	65/4749	238/18670	0.2739	0.5764	0.4689	TWIST1/TTC7A/NR4A3/PPARG/ABCG1/DGKD/GBGT1/MTMR3/SOCS2/TTC7B/MTOR/ABCD1/MECR/SOCS3/FA2H/ABCD2/DGKZ/SLC27A2/MCAT/EPHX2/TMEM150A/ACOX2/TYSND1/PIKFYVE/MTMR9/IMPA2/ACOT8/ADIPOR2/PIP5K1B/PI4K2A/GBA/ADIPOR1/SLA2/PRKAG2/CNR1/AMACR/ETFA/PEX2/INPP1/SLC35C1/BDH2/FAM126B/PIK3C3/IP6K1/ADIPOQ/CPT1A/POR/DGAT2/ACACB/ETFB/ACAD11/SPHK2/PIP4K2A/ECI1/IP6K2/AGK/PIP4K2B/PECR/PPARD/CYP4V2/PIP5K1A/PEX13/HADHB/SESN2/DECR2	65
BP	GO:0007257	activation of JUN kinase activity	12/4749	39/18670	0.274	0.5764	0.4689	PTPN1/MAP3K6/MAP3K2/MAP3K5/MAP3K11/MAP2K4/MAP4K1/ERN1/RIPK2/BIRC7/TNFSF11/MAP3K9	12
BP	GO:0033574	response to testosterone	12/4749	39/18670	0.274	0.5764	0.4689	SPP1/NASP/TSPO/CFLAR/GBA/ELK1/PSPH/TBXA2R/BGLAP/BAD/SIRT1/DUSP1	12
BP	GO:0050856	regulation of T cell receptor signaling pathway	12/4749	39/18670	0.274	0.5764	0.4689	PTPN6/LGALS3/CEACAM1/BTN2A2/LILRB4/RPS3/EZR/CYLD/DUSP22/KCNN4/THY1/PRNP	12
BP	GO:0006027	glycosaminoglycan catabolic process	18/4749	61/18670	0.2744	0.5765	0.469	SDC4/GLB1/HPSE/GPC1/HYAL3/IDS/OGN/IDUA/SDC2/SDC1/PGLYRP3/CHP1/GPC2/CD44/HEXB/GUSB/FUCA1/TGFB1	18
BP	GO:0042490	mechanoreceptor differentiation	18/4749	61/18670	0.2744	0.5765	0.469	MYO7A/NOTCH1/SDC4/JAG2/NTRK2/NTRK1/CDH23/CTHRC1/NTRK3/RBPJ/JAG1/WDPCP/TRIOBP/USH1G/SCRIB/IFT27/STRC/DLL1	18
BP	GO:0045604	regulation of epidermal cell differentiation	18/4749	61/18670	0.2744	0.5765	0.469	VDR/CD109/NOTCH1/CBFB/TP63/PTCH1/ZFP36/NUMA1/SFN/SFRP4/SGPP1/EZH2/CYP27B1/IL20/ZFP36L1/DLL1/TRIM16/NME2	18
BP	GO:0046513	ceramide biosynthetic process	18/4749	61/18670	0.2744	0.5765	0.469	SGMS1/SPTSSA/SGMS2/TNF/FA2H/P2RX1/GBA/ELOVL1/ASAH2/B4GALT5/ORMDL2/SPHK2/AGK/ST8SIA3/CERS3/ST6GALNAC6/P2RX7/ORMDL3	18
BP	GO:0030518	intracellular steroid hormone receptor signaling pathway	37/4749	132/18670	0.2753	0.5773	0.4697	KANK2/PMEPA1/CBFB/YWHAH/DNAJA1/CYP7B1/TGFB1I1/TP63/NR3C1/SRC/PPARGC1B/TRIP4/CRY1/PAK1/CARM1/CDK7/SMARCA4/PIAS1/ARID1A/PARK7/PPP5C/UBE3A/NCOA4/DDX17/DDX54/PIAS2/ARNTL/YAP1/PADI2/SFRP1/TAF7/ESR1/DEFA1B/LBH/STRN3/NCOR1/SIRT1	37
BP	GO:0009409	response to cold	15/4749	50/18670	0.2754	0.5773	0.4697	PLAC8/PPARG/HSPA2/THRA/ACOT11/CXCL10/CIRBP/FOXO1/NFKBIA/ADM/EIF2AK3/RBM3/FOS/METRNL/LRP11	15
BP	GO:0009948	anterior/posterior axis specification	15/4749	50/18670	0.2754	0.5773	0.4697	AURKA/SRF/SKI/TIFAB/TBX6/DDIT3/BASP1/EPB41L5/NRARP/TDRD5/LRP6/OTX2/FZD5/CER1/LDB1	15
BP	GO:0031113	regulation of microtubule polymerization	15/4749	50/18670	0.2754	0.5773	0.4697	FES/RAC1/HSPA1A/RANGRF/PSRC1/NUMA1/CLIP3/PAK1/RPS3/TERF1/STMN1/TUBB4A/ARL2/SLAIN2/CDH5	15
BP	GO:0032608	interferon-beta production	15/4749	50/18670	0.2754	0.5773	0.4697	IRF7/RELB/TLR8/SIRPA/TIRAP/IRF5/TLR4/TRAIP/TLR2/FLOT1/RNF216/NLRC3/IRF3/RIPK2/PTPRS	15
BP	GO:0032784	regulation of DNA-templated transcription, elongation	15/4749	50/18670	0.2754	0.5773	0.4697	CCNT2/BRD4/EZH2/SUPT6H/RECQL5/RNF8/CCNK/ZNF326/HTATSF1/ELL/TCEA2/POU4F1/EAPP/LDB1/RNF168	15
BP	GO:0060425	lung morphogenesis	15/4749	50/18670	0.2754	0.5773	0.4697	LIF/SRF/CTSH/TNF/NKX2-1/CTSZ/SOX11/YAP1/DLG5/FGF8/PLOD3/ID1/MAPK1/RDH10/ESRP2	15
BP	GO:0030148	sphingolipid biosynthetic process	29/4749	102/18670	0.2761	0.5786	0.4707	SGMS1/SPTSSA/SGMS2/KDSR/TNF/FA2H/P2RX1/SGPP1/ST8SIA1/PRKD3/GBA/ELOVL7/ACER1/ELOVL1/ACER2/ASAH2/B4GALT5/ALDH3B1/ASAH2B/ORMDL2/SPHK2/AGK/ST8SIA3/CERS3/CSNK1G2/ST6GALNAC6/PPM1L/P2RX7/ORMDL3	29
BP	GO:0016999	antibiotic metabolic process	42/4749	151/18670	0.2777	0.5817	0.4732	MTHFD1L/RAC1/NOXA1/CYBB/CTNS/GPX1/STAT3/PRDX3/OGDH/AMDHD1/PDHB/MTHFS/ALDH2/PRDX5/GNE/HBA2/MDH2/PINK1/GNPDA1/DLST/DLAT/PARK7/CS/ACO1/RAC2/MPO/ZNF205/CYBA/HBG1/IDH3B/PRDX6/ME3/ALDH3B1/HBB/NNT/ACSS1/ALDH5A1/CMAS/NAGK/AKR1A1/PRDX1/FYN	42
BP	GO:0030500	regulation of bone mineralization	22/4749	76/18670	0.2788	0.5839	0.475	TWIST1/ISG15/CCR1/BMP2K/WNT10B/NBR1/CCL3/TGFB3/FAM20C/BCOR/S1PR1/ATRAID/TRPM4/CYP27B1/ACVR2B/SRGN/BGLAP/FZD9/TXLNG/TMEM119/TGFB1/P2RX7	22
BP	GO:0006836	neurotransmitter transport	73/4749	269/18670	0.2802	0.5866	0.4773	SLC29A2/CSF2/ADORA2A/SLC6A6/SLC1A1/SLC6A8/PPFIA4/RIMS3/CDK5/SYN1/SYNGR3/NCS1/SLC36A1/CHRNA5/SLC29A1/STX11/HCRT/BLOC1S6/SEC14L1/P2RX1/ABAT/SYT4/BTK/SNAP47/HTR2A/CAMK2A/SLC22A3/SLC6A16/PPT1/SNAP29/PFN2/PER2/APBA2/STX1B/DVL1/FLOT1/SCRIB/STX19/DRD1/SNAP23/DTNBP1/WNT7A/PPFIA3/CNR1/NTSR1/PARK7/FMR1/SYT11/TACR2/PRAF2/ERC2/SNAPIN/NAPB/MCTP2/KCNC4/STX2/HBB/RPH3A/DOC2B/CHRNA3/PRKCB/SLC6A20/P2RY1/SYN2/CACNB2/FBXL20/TNFSF11/LIN7C/SV2A/PDZD11/P2RX7/TRIM9/SLC44A1	73
BP	GO:0010811	positive regulation of cell-substrate adhesion	34/4749	121/18670	0.2805	0.5871	0.4777	VEGFA/SDC4/ITGA3/NEDD9/RAC1/CSF1/NINJ1/MYADM/DOCK1/LIMS1/NID1/DOCK5/EMILIN2/PREX1/TRIOBP/PLEKHA2/ITGA6/VTN/S100A10/THY1/UNC13D/EPB41L5/CRK/PRKCE/CD3E/SFRP1/UTRN/C1QBP/ARL2/CDC42/HAS2/FMN1/ILK/RAC3	34
BP	GO:0007041	lysosomal transport	30/4749	106/18670	0.2811	0.588	0.4784	GRN/CHMP2B/HSPA1A/UBXN6/SORL1/DTX3L/VCP/CLU/M6PR/PINK1/TMEM106B/CACNG3/VPS51/AP3D1/LRP1/HMGXB4/HGS/HOOK2/NCOA4/MGRN1/VPS52/AP4M1/SNAPIN/LAMP1/DENND3/VPS39/EHD3/CCDC91/CHMP3/RAB12	30
BP	GO:0090287	regulation of cellular response to growth factor stimulus	79/4749	292/18670	0.2812	0.588	0.4784	CXCL13/SKIL/IL1B/CD109/VEGFA/NOTCH1/SULF2/ITGA3/CDKN2B/LRG1/PMEPA1/CYFIP1/SNX25/GPC1/TGFB1I1/HSPA5/HSPA1A/SKI/TMPRSS6/PTPN1/MSX1/DAND5/SMAD7/SORL1/CYFIP2/NKX2-1/NUMA1/CFLAR/SDCBP/GREM2/NTRK3/PELO/UBB/SFRP4/TGFB3/MYOF/FGF9/RBPJ/PRDM16/FAM20C/SMAD6/RUNX2/RPS27A/SMURF1/FAM89B/UBA52/VTN/LEMD3/HGS/FLT1/VASN/LDLRAD4/TFAP2B/FKBP8/RBPMS2/EID2/CITED2/SOX11/ZNF703/HTRA4/SFRP1/PRKCB/OTX2/FBXL15/NTF3/DLL1/CER1/HTRA1/TGFB1/ZNF451/CDH5/VEPH1/MIR17HG/GATA3/VEGFC/PTP4A3/ILK/SLC9A6/SIRT1	79
BP	GO:0006026	aminoglycan catabolic process	19/4749	65/18670	0.2821	0.589	0.4792	SDC4/GLB1/HPSE/GPC1/HYAL3/IDS/OGN/IDUA/SDC2/SDC1/OVGP1/PGLYRP3/CHP1/GPC2/CD44/HEXB/GUSB/FUCA1/TGFB1	19
BP	GO:0007219	Notch signaling pathway	53/4749	193/18670	0.2826	0.589	0.4792	NOTCH1/JAG2/CHAC1/DLGAP5/BCL6/TSPAN5/PERP/TIMP4/TP63/ASCL1/MAML1/IL2RA/TRAF7/STAT3/ERH/MAML2/SNAI1/DTX3L/DTX3/ARRB1/CFD/RBPJ/ENHO/CBFA2T2/SYNJ2BP/JAG1/RPS19/PRKCI/PLXND1/NOD2/DTX4/IFT172/AAK1/CD46/ANXA4/NFKBIA/SLC35C1/DTX1/NRARP/KRT19/POGLUT1/GDPD5/EGFL7/WDR12/YBX1/ARRDC1/DTX2/HIF1AN/STAT1/PBX1/DLL1/TGFB1/PTP4A3	53
BP	GO:0006739	NADP metabolic process	10/4749	32/18670	0.2826	0.589	0.4792	PGAM1/TP53I3/NADK/SHPK/NUDT17/FMO2/NNT/RPE/PGD/ASPDH	10
BP	GO:0035510	DNA dealkylation	10/4749	32/18670	0.2826	0.589	0.4792	APOBEC3H/MPG/USP9X/APOBEC3B/ALKBH2/ALKBH5/AICDA/MGMT/GATA3/ALKBH3	10
BP	GO:0042491	inner ear auditory receptor cell differentiation	10/4749	32/18670	0.2826	0.589	0.4792	MYO7A/NOTCH1/JAG2/RBPJ/JAG1/WDPCP/TRIOBP/SCRIB/STRC/DLL1	10
BP	GO:0042744	hydrogen peroxide catabolic process	10/4749	32/18670	0.2826	0.589	0.4792	GPX1/PRDX3/PRDX5/HBA2/MPO/HBG1/PRDX6/HBB/NNT/PRDX1	10
BP	GO:0045987	positive regulation of smooth muscle contraction	10/4749	32/18670	0.2826	0.589	0.4792	ITGA2/SRF/ADRA2B/CTTN/ABAT/TACR2/TBXA2R/GHRL/F2R/PTAFR	10
BP	GO:0046949	fatty-acyl-CoA biosynthetic process	10/4749	32/18670	0.2826	0.589	0.4792	SLC25A1/TECR/SCD/PPT1/ACSL1/HSD17B8/ELOVL7/ELOVL1/ACSL4/FASN	10
BP	GO:0048841	regulation of axon extension involved in axon guidance	10/4749	32/18670	0.2826	0.589	0.4792	VEGFA/SEMA4C/SEMA7A/SEMA3G/SEMA6C/SEMA6B/SEMA3B/SEMA5B/SEMA4D/SEMA5A	10
BP	GO:0055094	response to lipoprotein particle	10/4749	32/18670	0.2826	0.589	0.4792	PPARG/CD68/CD9/TLR4/ADTRP/LDLR/CASR/ABCA1/TLR6/SREBF2	10
BP	GO:0060317	cardiac epithelial to mesenchymal transition	10/4749	32/18670	0.2826	0.589	0.4792	TWIST1/NOTCH1/MSX1/PDCD4/SNAI1/RBPJ/JAG1/ADAM15/FGF8/HAS2	10
BP	GO:0072073	kidney epithelium development	39/4749	140/18670	0.2832	0.5898	0.4799	LIF/VEGFA/NOTCH1/SDC4/KANK2/MYO1E/PTCH1/DCHS1/SMAD7/WWTR1/KLHL3/PKD2/SMAD6/JAG1/HOXB7/SDC1/GREB1L/SOX8/BASP1/TFAP2B/YAP1/SMAD1/SFRP1/ADIPOQ/CD34/UMOD/HOXA11/FGF8/STAT1/PBX1/DLL1/CER1/TGFB1/KIF26B/RARA/FMN1/LAMA5/GATA3/ILK	39
BP	GO:0097553	calcium ion transmembrane import into cytosol	39/4749	140/18670	0.2832	0.5898	0.4799	PTPN6/CHERP/JSRP1/NOL3/BAX/CXCL10/TRPC1/MYO5A/PDE4D/HTR2A/CCL3/SRI/PKD2/CCR5/HTT/GSTO1/TPCN1/PTPRC/CORO1A/RASA3/CXCL9/DRD1/FKBP1A/ATP2B4/DDIT3/THY1/CD19/NTSR1/PRKCE/CYBA/LACRT/IL13/CAMK2D/PRNP/F2R/PLCB1/TGFB1/P2RX7/FYN	39
BP	GO:0050994	regulation of lipid catabolic process	16/4749	54/18670	0.2846	0.5922	0.4818	TWIST1/IL1B/THRA/TNF/MTOR/LDLR/ABCD1/SORL1/ABCD2/TYSND1/CNR1/PRKCE/RARRES2/CPT1A/BSCL2/ACACB	16
BP	GO:0051353	positive regulation of oxidoreductase activity	16/4749	54/18670	0.2846	0.5922	0.4818	VDR/IL1B/TNF/COX17/RIPK3/FXN/DHFR/NOD2/GNAI2/PARK7/CYP27B1/CYBA/POR/CCS/PPM1K/TERF2	16
BP	GO:0009063	cellular amino acid catabolic process	35/4749	125/18670	0.2848	0.5922	0.4818	BCAT1/IL4I1/DDAH2/SDS/BCKDK/MPST/CARNS1/TST/GLS2/ABAT/GLDC/OGDH/AMDHD1/SARDH/HMGCL/GPT/CTH/GCAT/ENOSF1/DLST/ATP2B4/ARG1/MTRR/IDO1/GLUD1/FAH/HGD/HIBADH/GPT2/ALDH7A1/AMT/PPM1K/ALDH5A1/GSTZ1/ADHFE1	35
BP	GO:0048194	Golgi vesicle budding	23/4749	80/18670	0.2852	0.5922	0.4818	SEC13/GORASP1/SEC24D/MCFD2/F5/STX5/SEC16A/CNIH2/ANKRD28/TBC1D20/PRKCI/INSIG1/TMED9/GBF1/TMED10/CTSZ/TRAPPC4/RAB1A/PPP6C/PEF1/PPP6R1/RAB1B/USO1	23
BP	GO:0006775	fat-soluble vitamin metabolic process	13/4749	43/18670	0.2853	0.5922	0.4818	VDR/IL1B/VKORC1L1/TNF/VKORC1/SNAI1/CYP26C1/CYP27B1/CUBN/PIAS4/CYP4F12/CYP11A1/PPARD	13
BP	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress	13/4749	43/18670	0.2853	0.5922	0.4818	GSKIP/MELK/MCL1/SFPQ/PML/NOL3/GPX1/MAP3K5/PINK1/PARK7/STK25/VNN1/SIRT1	13
BP	GO:0010863	positive regulation of phospholipase C activity	13/4749	43/18670	0.2853	0.5922	0.4818	GNA15/NTRK2/HTR2A/NTRK3/TXK/FLT1/RASGRP4/ITK/ESR1/GNAQ/NTF3/NMUR1/PTAFR	13
BP	GO:0033173	calcineurin-NFAT signaling cascade	13/4749	43/18670	0.2853	0.5922	0.4818	CHERP/TNF/SPPL3/MTOR/HOMER2/PTBP1/LMCD1/C10orf71/ATP2B4/CHP1/CAMTA1/LACRT/PRNP	13
BP	GO:0045687	positive regulation of glial cell differentiation	13/4749	43/18670	0.2853	0.5922	0.4818	LIF/NOTCH1/TP73/PPARG/TTBK1/MTOR/SPINT1/TLR2/PRPF19/TNFRSF1B/DICER1/NKX6-2/TGFB1	13
BP	GO:0045746	negative regulation of Notch signaling pathway	13/4749	43/18670	0.2853	0.5922	0.4818	JAG2/CHAC1/BCL6/ARRB1/CBFA2T2/JAG1/NFKBIA/SLC35C1/NRARP/GDPD5/EGFL7/ARRDC1/HIF1AN	13
BP	GO:0010466	negative regulation of peptidase activity	71/4749	262/18670	0.2882	0.5964	0.4852	FURIN/CD109/VEGFA/BIRC5/ADORA2A/MICAL1/KLF4/SERPINB6/PTTG1/GAPDH/PLAUR/RFFL/TIMP4/SERPINB8/TIMP2/MMP9/YWHAE/HMSD/PROS1/NOL3/SERPINE1/TNFAIP8/GPX1/SORL1/CST5/SRC/IFI6/PRDX3/CSTA/SFN/CFLAR/ARRB1/CST3/BST2/HERPUD1/PRDX5/PSMF1/SPINT1/UBXN1/ITIH3/SPOCK3/A2M/VTN/PARK7/TFAP2B/CRIM1/BCL2L12/TIMP1/CD44/RECK/UCHL5/SIAH2/BIRC3/SERPING1/IFI16/LCN1/DNAJB6/POR/CST6/CSN2/TIMP3/BIRC7/CARD8/SERPINA4/SERPINA10/ITIH6/CST1/CST2/TFPI/SSPO/PAK2	71
BP	GO:0010876	lipid localization	107/4749	400/18670	0.2884	0.5964	0.4852	IL1B/PPARG/ABCC1/ABCG1/NMB/ANXA2P2/PCTP/CEACAM1/MFSD2A/ATP11A/PRELID1/SPP1/PTCH1/ATP8B4/TNF/GM2A/GRAMD1C/OSBP2/ANXA2/LDLR/ABCD1/PITPNA/APOL5/FFAR2/TSPO/SORL1/FITM2/LRP10/SLC27A2/PLA2G12A/CLU/FITM1/C2CD2L/APOL4/CRY1/MAP2K6/ACSL1/PITPNM1/SGPP1/SLC51A/NME4/PRKAB2/GRAMD1B/CFHR4/KDM5B/VPS51/ABCA1/KCNN4/LRP1/STARD10/TMEM30A/SLCO3A1/STX12/RXRA/BDKRB2/PRKAG2/NTSR1/ABCB4/ACVR1C/PLEKHA8/MEST/NFKBIA/ATP10A/PLIN2/ZC3H12A/MFSD2B/ATP8B3/SQLE/ABCA5/ACSL4/APOL1/LCN1/ATP10D/GHRL/ADIPOQ/CPT1A/BSCL2/PLA2G2A/ARV1/DGAT2/PLA2G2C/SLC27A4/LDLRAP1/ACACB/TEX2/LRP6/APOBR/CETP/OSBPL7/HEXB/TNFAIP8L3/GLTPD2/APOL6/ATP11C/TTC39B/TNFSF11/ABCA3/GRAMD1A/PLA2G5/PPARD/TMF1/PLEKHA3/P2RX7/NCOR1/SREBF2/OSBPL9/SIRT1	107
BP	GO:0030166	proteoglycan biosynthetic process	20/4749	69/18670	0.2893	0.5964	0.4852	HS3ST3B1/HS3ST3A1/CHST15/CANT1/CHPF2/B3GAT3/CSGALNACT1/SLC35D1/TCF7L2/B3GALT6/CHST7/EXT1/EXTL2/DSEL/HS6ST1/CHPF/HS3ST4/GAL3ST4/CHST13/XYLT1	20
BP	GO:0036465	synaptic vesicle recycling	20/4749	69/18670	0.2893	0.5964	0.4852	CYFIP1/CDK5/ACTG1/GRIPAP1/STON2/SLC2A4/SH3GL1/STX1B/AP3D1/SCRIB/WNT7A/DNAJC6/SYT11/NLGN4Y/DNM1/CANX/PACSIN1/ARF6/KIAA1107/ACTB	20
BP	GO:0050771	negative regulation of axonogenesis	20/4749	69/18670	0.2893	0.5964	0.4852	CDK5/SPP1/SEMA4C/SEMA7A/SEMA3G/SEMA6C/SEMA6B/LRP4/FGF13/ARHGAP4/THY1/SEMA3B/SEMA5B/PTPRS/SEMA4D/ARHGDIA/RUFY3/SEMA5A/RTN4R/GDI1	20
BP	GO:0051865	protein autoubiquitination	20/4749	69/18670	0.2893	0.5964	0.4852	UBE2A/UHRF1/DDB2/UBE2B/DTX3L/UBE3D/RNF187/ERCC8/TRIM13/RNF8/RNF19B/RNF213/UBE3A/RNF133/TRAF2/LRSAM1/TRAF6/MTA1/UHRF2/RNF186	20
BP	GO:0006690	icosanoid metabolic process	32/4749	114/18670	0.2905	0.5964	0.4852	IL1B/ABCC1/PTGIS/ALOX5AP/CYP2S1/ABHD16A/CYP4F22/GPX1/PON2/GGT1/FABP5/CD74/EPHX2/TLR2/ALOX5/GGTLC2/ZADH2/GPX4/TBXAS1/PIBF1/PTGES2/CYP2C18/CYP4F12/MAPKAPK2/MGST2/GGT7/CYP2D6/MGST3/HPGD/CYP2U1/PLA2G5/SIRT1	32
BP	GO:0015749	monosaccharide transmembrane transport	32/4749	114/18670	0.2905	0.5964	0.4852	IL1B/NR4A3/TNF/SIRT6/SLC2A8/HK2/PEA15/SLC2A3/SLC5A3/CLIP3/FABP5/SLC2A4/RSC1A1/PRKCI/ADIPOR2/SLC45A3/DRD1/PRKAG2/GSK3A/CREBL2/SLC2A11/BRAF/ADIPOQ/SLC2A14/SLC23A2/SLC5A4/PRKCB/INSR/PPBP/PPARD/SESN2/TRIB3	32
BP	GO:0051592	response to calcium ion	41/4749	148/18670	0.2907	0.5964	0.4852	RASGRP2/PPIF/TXNIP/WNK1/CPNE7/ALOX5AP/FOSB/HSPA5/TRPC1/SLC25A23/HOMER1/SYT4/CPNE5/PKD2/CASR/SDC1/KCNMB1/ANXA5/JUN/RASA4/ACER1/SYT11/ECT2/RASAL1/CLIC4/BRAF/CAMK2D/AANAT/MNAT1/CPNE4/FOS/SYT15/CCND1/ADAM9/PEF1/AMELX/GDI1/P2RX7/GIPR/BAD/DUSP1	41
BP	GO:0000729	DNA double-strand break processing	8/4749	25/18670	0.2909	0.5964	0.4852	RBBP8/UBE2N/DNA2/HELB/RAD52/ATM/RNF138/BARD1	8
BP	GO:0009404	toxin metabolic process	8/4749	25/18670	0.2909	0.5964	0.4852	AS3MT/ETHE1/MPST/PAM/CTH/N6AMT1/SP1/FMO2	8
BP	GO:0019430	removal of superoxide radicals	8/4749	25/18670	0.2909	0.5964	0.4852	TNF/NQO1/DHFR/FANCC/PARK7/MPO/CCS/PRDX1	8
BP	GO:0031639	plasminogen activation	8/4749	25/18670	0.2909	0.5964	0.4852	ENO1/ANXA2P2/PLAU/SERPINE1/ANXA2/PLAT/CTSZ/KLKB1	8
BP	GO:0032400	melanosome localization	8/4749	25/18670	0.2909	0.5964	0.4852	BBS2/MYO5A/BLOC1S6/VPS33B/MKKS/RAB27A/ASIP/RAB1A	8
BP	GO:0032509	endosome transport via multivesicular body sorting pathway	8/4749	25/18670	0.2909	0.5964	0.4852	CHMP2B/UBXN6/SNF8/VCP/TMEM50A/CHMP1A/CHMP2A/CHMP3	8
BP	GO:0035336	long-chain fatty-acyl-CoA metabolic process	8/4749	25/18670	0.2909	0.5964	0.4852	TECR/THEM5/FAR2/ACSL1/ELOVL7/ELOVL1/ACSL4/DGAT2	8
BP	GO:0035459	cargo loading into vesicle	8/4749	25/18670	0.2909	0.5964	0.4852	SEC13/SEC24D/CTAGE4/TBC1D20/INSIG1/TMED10/CTAGE9/RAB1A	8
BP	GO:0045724	positive regulation of cilium assembly	8/4749	25/18670	0.2909	0.5964	0.4852	KCTD17/CENPJ/ATMIN/HTT/ARHGAP35/ZMYND10/MARK4/WRAP73	8
BP	GO:0045830	positive regulation of isotype switching	8/4749	25/18670	0.2909	0.5964	0.4852	TNFSF4/TFRC/TP53BP1/PTPRC/TNFSF13/IL4/MAD2L2/TGFB1	8
BP	GO:0048103	somatic stem cell division	8/4749	25/18670	0.2909	0.5964	0.4852	NOTCH1/ASPM/TEAD3/ARHGEF2/ZFP36L2/FGF13/WNT7A/LBH	8
BP	GO:0070199	establishment of protein localization to chromosome	8/4749	25/18670	0.2909	0.5964	0.4852	BRCA2/CCT5/TERF1/ACD/POT1/WRAP53/LRWD1/CCT3	8
BP	GO:0090025	regulation of monocyte chemotaxis	8/4749	25/18670	0.2909	0.5964	0.4852	CCR1/HMGB1/CXCL10/SERPINE1/CCR2/AIF1/FPR2/DUSP1	8
BP	GO:1900101	regulation of endoplasmic reticulum unfolded protein response	8/4749	25/18670	0.2909	0.5964	0.4852	HSPA5/BAX/PTPN1/BAK1/FICD/ERN1/PPP1R15A/TMEM33	8
BP	GO:2000482	regulation of interleukin-8 secretion	8/4749	25/18670	0.2909	0.5964	0.4852	LGALS9/FFAR2/FCN1/TLR2/CD58/TLR6/ANXA4/F2R	8
BP	GO:0072511	divalent inorganic cation transport	130/4749	489/18670	0.2932	0.5964	0.4852	VDR/GEM/ICAM1/ADORA2A/SLC39A1/HSPA2/PTPN6/CCR1/SESTD1/ORAI2/CDK5/ANXA2P2/LGALS3/SLC39A7/YWHAE/CHERP/PML/NIPAL4/TSPAN13/CDH23/JSRP1/CHRNA10/NCS1/NOL3/BAX/CXCL10/TRPC1/LILRA2/SLC25A23/ANXA2/HOMER2/TSPO/MYO5A/HCRT/REM1/P2RX1/HOMER1/PDE4D/HTR2A/ATP2A1/CCL3/CAMK2A/KCNE3/PDE4B/SRI/MICU1/CD33/CYSLTR1/TCN1/KCNJ2/SLC3A2/PKD2/SLC25A25/CCR5/HTT/TCN2/CCL2/SLC39A11/PARL/GPR35/ATP1B1/CASR/GSTO1/TPCN1/PTPRC/CNNM4/REM2/CORO1A/TRPM4/RASA3/ANXA5/CACNG3/STAC3/ORAI3/CXCL9/KCNN4/BAK1/DRD1/LILRB2/FKBP1A/ATP2B4/STAC/DDIT3/THY1/CD19/CACNA2D2/SUMO1/GNAI2/NTSR1/SLC24A3/VDAC1/CYP27B1/FMR1/CAMK2G/PRKCE/CUL5/GRIN3B/CYBA/LILRA5/LACRT/IL13/SLC41A2/CAMK2D/P2RX5/PRNP/ISCU/F2R/CSN2/EPB41/PRKCB/TRPC7/AHNAK/SPHK2/CACNB2/TMC2/CATSPER2/EHD3/CLCA1/FFAR1/PLCB1/SLC39A10/TGFB1/NMUR1/TRPC5/SPG7/PDGFB/SLC40A1/P2RX7/SLC35G1/FYN	130
BP	GO:0010634	positive regulation of epithelial cell migration	47/4749	171/18670	0.2946	0.5964	0.4852	HBEGF/VEGFA/ITGA2/ITGA3/CTSH/GRN/MMP9/GPI/HMGB1/PLK2/AKT3/MTOR/CCR6/SRC/HMOX1/MAPRE2/MAP2K3/DOCK1/DOCK5/PRKCA/CLASP2/ATOH8/SP1/IQSEC1/WNT7A/JUN/EPB41L5/PRKCE/MAP3K3/ZC3H12A/FLT4/EMC10/INSL3/GLIPR2/STAT5A/CAPN7/ARF6/HDAC9/TGFB1/BCAS3/SEMA5A/HAS2/ADAM9/PDGFB/GATA3/VEGFC/SIRT1	47
BP	GO:0048659	smooth muscle cell proliferation	47/4749	171/18670	0.2946	0.5964	0.4852	HBEGF/IL18/CDKN1A/NR4A3/PPARG/ITGA2/IL10/TRIB1/KLF4/MMP9/TNF/MTOR/PDCD4/HMOX1/TGM2/OGN/TGFB3/PAK1/FGF9/XRCC6/IGFBP3/S1PR1/TCF7L2/MAP3K5/NAMPT/MEF2D/AIF1/IRAK1/NDRG2/GNAI2/JUN/RBPMS2/CYBA/IL13/ADIPOQ/ERN1/LDLRAP1/MNAT1/TRAF6/TPM1/STAT1/HPGD/ADAMTS1/PPARD/PDGFB/PTAFR/ILK	47
BP	GO:0061383	trabecula morphogenesis	14/4749	47/18670	0.2954	0.5964	0.4852	NOTCH1/SRF/PLXNB1/SBNO2/WNT10B/PPARGC1B/RBPJ/S1PR1/FKBP1A/SFRP1/SEMA4D/BMP10/ADAMTS1/SLC40A1	14
BP	GO:0070849	response to epidermal growth factor	14/4749	47/18670	0.2954	0.5964	0.4852	ASCL1/SYAP1/ZFP36/BAG4/CFLAR/MCM7/ZFP36L2/DUSP22/NCL/EEF1A1/ERBB2/ZFP36L1/ID1/MAPK1	14
BP	GO:2001239	regulation of extrinsic apoptotic signaling pathway in absence of ligand	14/4749	47/18670	0.2954	0.5964	0.4852	IL1B/CSF2/MCL1/PPP2R1A/TNF/HSPA1A/IFI6/EYA2/STRADB/WWOX/BCL2L1/IL7/CTNNA1/FYN	14
BP	GO:0000154	rRNA modification	11/4749	36/18670	0.2957	0.5964	0.4852	NSUN4/NOP10/NSUN5P1/TRMT112/EMG1/FBL/FDXACB1/RRNAD1/METTL16/ZCCHC4/TFB2M	11
BP	GO:0000578	embryonic axis specification	11/4749	36/18670	0.2957	0.5964	0.4852	STIL/PTCH1/SMAD6/TIFAB/TBX6/WNT7A/BASP1/EPB41L5/NRARP/TDRD5/FZD5	11
BP	GO:0006699	bile acid biosynthetic process	11/4749	36/18670	0.2957	0.5964	0.4852	HSD3B7/CH25H/CYP7B1/SLC27A2/ACOX2/ACOT8/AMACR/OSBPL7/CYP7A1/OSBPL9/SIRT1	11
BP	GO:0034314	Arp2/3 complex-mediated actin nucleation	11/4749	36/18670	0.2957	0.5964	0.4852	CYFIP1/CORO1B/WHAMMP3/HIP1R/ARPC1B/PICK1/ARPC5/ACTR3B/WHAMM/AP1AR/WAS	11
BP	GO:0042554	superoxide anion generation	11/4749	36/18670	0.2957	0.5964	0.4852	ACP5/CLEC7A/NOXA1/CYBB/CD177/GNAI2/FPR2/CYBA/TYROBP/NCF1/TGFB1	11
BP	GO:0071634	regulation of transforming growth factor beta production	11/4749	36/18670	0.2957	0.5964	0.4852	FURIN/LGALS9/CD200/FOXP3/ITGB8/CD46/IL13/CD2AP/CD34/TYROBP/LRRC32	11
BP	GO:0090322	regulation of superoxide metabolic process	11/4749	36/18670	0.2957	0.5964	0.4852	ACP5/CLEC7A/TNF/CD177/DHFR/GNAI2/FPR2/PARK7/CYBA/TYROBP/TGFB1	11
BP	GO:0097242	amyloid-beta clearance	11/4749	36/18670	0.2957	0.5964	0.4852	SRF/TNF/LDLR/CLU/IGF1R/LRP4/LRPAP1/LRP1/IFNGR1/IL4/INSR	11
BP	GO:1902622	regulation of neutrophil migration	11/4749	36/18670	0.2957	0.5964	0.4852	IL1R1/RAC1/TIRAP/DAPK2/CD74/C3AR1/RAC2/CD99L2/C1QBP/THBS4/IL23A	11
BP	GO:0009988	cell-cell recognition	21/4749	73/18670	0.2961	0.5964	0.4852	EPHB1/LGALS3/CD9/ASTL/DOCK8/HAVCR2/CCT5/OVGP1/HVCN1/KCNU1/ATP8B3/PAEP/ZP1/ALDOA/PCSK4/CD6/HSPA1L/ADAM20/CATSPER2/ST6GALNAC6/CCT3	21
BP	GO:0045685	regulation of glial cell differentiation	21/4749	73/18670	0.2961	0.5964	0.4852	LIF/NOTCH1/TP73/CDK1/PPARG/DUSP10/TTBK1/TNFRSF21/MTOR/LDLR/NTRK3/SPINT1/TLR2/SLC45A3/WDR1/PRPF19/TNFRSF1B/DICER1/MBD1/NKX6-2/TGFB1	21
BP	GO:0050684	regulation of mRNA processing	38/4749	137/18670	0.2968	0.5964	0.4852	NUP98/CCNB1/SMU1/IWS1/PTBP1/RNPS1/SRSF4/ZC3H3/CIRBP/RNF40/SLTM/FAM172A/SUPT6H/CELF6/RBM4B/SF3B4/FMR1/DDX17/MBNL3/RBM17/PRPF19/C9orf78/MAGOH/RBMY1B/PRDX6/METTL16/RBM11/ZFP36L1/CPEB1/C1QBP/CPSF6/HNRNPL/PAPOLA/RBM3/NCBP2/CWC22/YTHDC1/BARD1	38
BP	GO:0106027	neuron projection organization	25/4749	88/18670	0.2969	0.5964	0.4852	ITGA3/SIPA1L1/EPHB1/CDK5/LRP8/CTTN/ABCD1/ABCD2/TIAM1/HOMER1/IGF1R/PAK3/PICK1/CFL1/DVL1/TANC1/WNT7A/UBE3A/ARHGAP33/PRNP/MAP1A/INSR/CDC42/FYN/DLG4	25
BP	GO:1901888	regulation of cell junction assembly	25/4749	88/18670	0.2969	0.5964	0.4852	VEGFA/SDC4/RAC1/CBFB/CORO1C/TNF/SRC/SNAI1/LIMS1/CLASP2/WDPCP/LIMCH1/DUSP22/FLOT1/S100A10/LRP1/THY1/RAPGEF1/EPB41L5/RAPGEF2/SFRP1/FZD5/BCAS3/FMN1/LDB1	25
BP	GO:0002098	tRNA wobble uridine modification	6/4749	18/18670	0.2977	0.5964	0.4852	CTU1/GTPBP3/ALKBH8/ELP5/ELP4/KTI12	6
BP	GO:0006349	regulation of gene expression by genetic imprinting	6/4749	18/18670	0.2977	0.5964	0.4852	PRMT7/EED/PCGF6/PCGF5/ARID4A/ZFP57	6
BP	GO:0007194	negative regulation of adenylate cyclase activity	6/4749	18/18670	0.2977	0.5964	0.4852	AKAP5/P2RY13/CCR2/GNAI2/LTB4R2/GALR2	6
BP	GO:0009048	dosage compensation by inactivation of X chromosome	6/4749	18/18670	0.2977	0.5964	0.4852	UPF1/PCGF6/RLIM/PCGF5/CDYL/YTHDC1	6
BP	GO:0010832	negative regulation of myotube differentiation	6/4749	18/18670	0.2977	0.5964	0.4852	NOTCH1/CXCL10/CFLAR/CEACAM5/BHLHE41/TMEM119	6
BP	GO:0010878	cholesterol storage	6/4749	18/18670	0.2977	0.5964	0.4852	PPARG/ABCG1/ABCA1/TTC39B/PPARD/SREBF2	6
BP	GO:0021756	striatum development	6/4749	18/18670	0.2977	0.5964	0.4852	BBS2/HPRT1/MKKS/DRD1/ZSWIM6/SLITRK5	6
BP	GO:0031065	positive regulation of histone deacetylation	6/4749	18/18670	0.2977	0.5964	0.4852	VEGFA/BCL6/PINK1/C6orf89/CTBP1/TGFB1	6
BP	GO:0034199	activation of protein kinase A activity	6/4749	18/18670	0.2977	0.5964	0.4852	ADCY4/ADCY6/PRRC1/ADCY3/PRKACB/ADCY9	6
BP	GO:0039692	single stranded viral RNA replication via double stranded DNA intermediate	6/4749	18/18670	0.2977	0.5964	0.4852	TOP2A/APOBEC3H/SMARCB1/MORC2/AICDA/SETDB1	6
BP	GO:0051782	negative regulation of cell division	6/4749	18/18670	0.2977	0.5964	0.4852	AURKB/TXNIP/ASPM/E2F7/E2F8/PTCH1	6
BP	GO:0051895	negative regulation of focal adhesion assembly	6/4749	18/18670	0.2977	0.5964	0.4852	CORO1C/SRC/CLASP2/DUSP22/LRP1/BCAS3	6
BP	GO:0051957	positive regulation of amino acid transport	6/4749	18/18670	0.2977	0.5964	0.4852	ADORA2A/ABAT/SYT4/CCK/NTSR1/P2RX7	6
BP	GO:0071605	monocyte chemotactic protein-1 production	6/4749	18/18670	0.2977	0.5964	0.4852	TWIST1/IL1B/CLEC7A/LGALS9/C1QTNF3/ADIPOQ	6
BP	GO:0071637	regulation of monocyte chemotactic protein-1 production	6/4749	18/18670	0.2977	0.5964	0.4852	TWIST1/IL1B/CLEC7A/LGALS9/C1QTNF3/ADIPOQ	6
BP	GO:0097094	craniofacial suture morphogenesis	6/4749	18/18670	0.2977	0.5964	0.4852	TWIST1/TGFB3/TIFAB/INSIG1/RAB23/TGFB1	6
BP	GO:0150078	positive regulation of neuroinflammatory response	6/4749	18/18670	0.2977	0.5964	0.4852	IL1B/IL18/TTBK1/TNF/CCL3/NUPR1	6
BP	GO:0150079	negative regulation of neuroinflammatory response	6/4749	18/18670	0.2977	0.5964	0.4852	GRN/CD200/LDLR/PTPRC/IL4/TNFRSF1B	6
BP	GO:2000319	regulation of T-helper 17 cell differentiation	6/4749	18/18670	0.2977	0.5964	0.4852	NLRP3/FOXP3/SMAD7/IL12RB1/ZC3H12A/IL23A	6
BP	GO:2000479	regulation of cAMP-dependent protein kinase activity	6/4749	18/18670	0.2977	0.5964	0.4852	HTT/ATP2B4/RAPGEF2/ADIPOQ/SESN2/SIRT1	6
BP	GO:0001778	plasma membrane repair	4/4749	11/18670	0.2987	0.5964	0.4852	MYH10/MYOF/SYT11/MYH9	4
BP	GO:0002730	regulation of dendritic cell cytokine production	4/4749	11/18670	0.2987	0.5964	0.4852	TLR4/BST2/NOD2/JAK3	4
BP	GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	4/4749	11/18670	0.2987	0.5964	0.4852	PTPN6/TNF/PTPRC/LTA	4
BP	GO:0003093	regulation of glomerular filtration	4/4749	11/18670	0.2987	0.5964	0.4852	CYBA/F2R/PDGFB/GJA5	4
BP	GO:0006054	N-acetylneuraminate metabolic process	4/4749	11/18670	0.2987	0.5964	0.4852	GNE/GNPDA1/CMAS/NAGK	4
BP	GO:0006558	L-phenylalanine metabolic process	4/4749	11/18670	0.2987	0.5964	0.4852	IL4I1/FAH/HGD/GSTZ1	4
BP	GO:0006559	L-phenylalanine catabolic process	4/4749	11/18670	0.2987	0.5964	0.4852	IL4I1/FAH/HGD/GSTZ1	4
BP	GO:0006620	posttranslational protein targeting to endoplasmic reticulum membrane	4/4749	11/18670	0.2987	0.5964	0.4852	HSPA5/SEC61A2/SGTA/SEC61B	4
BP	GO:0006853	carnitine shuttle	4/4749	11/18670	0.2987	0.5964	0.4852	PRKAB2/PRKAG2/CPT1A/ACACB	4
BP	GO:0007256	activation of JNKK activity	4/4749	11/18670	0.2987	0.5964	0.4852	NRK/MAP3K11/RIPK2/MAP3K9	4
BP	GO:0009125	nucleoside monophosphate catabolic process	4/4749	11/18670	0.2987	0.5964	0.4852	HPRT1/NUDT3/AMPD3/NT5E	4
BP	GO:0015791	polyol transport	4/4749	11/18670	0.2987	0.5964	0.4852	SLC5A3/AQP2/SLC26A6/AQP7	4
BP	GO:0019042	viral latency	4/4749	11/18670	0.2987	0.5964	0.4852	IRF7/XRCC6/BANF1/NUCKS1	4
BP	GO:0030241	skeletal muscle myosin thick filament assembly	4/4749	11/18670	0.2987	0.5964	0.4852	MYBPC3/MYOM1/TCAP/MYBPC2	4
BP	GO:0032060	bleb assembly	4/4749	11/18670	0.2987	0.5964	0.4852	EMP1/ANLN/PMP22/P2RX7	4
BP	GO:0032306	regulation of prostaglandin secretion	4/4749	11/18670	0.2987	0.5964	0.4852	IL1B/MAP2K6/TNFSF11/P2RX7	4
BP	GO:0032377	regulation of intracellular lipid transport	4/4749	11/18670	0.2987	0.5964	0.4852	ANXA2P2/ANXA2/ARV1/LDLRAP1	4
BP	GO:0032380	regulation of intracellular sterol transport	4/4749	11/18670	0.2987	0.5964	0.4852	ANXA2P2/ANXA2/ARV1/LDLRAP1	4
BP	GO:0032383	regulation of intracellular cholesterol transport	4/4749	11/18670	0.2987	0.5964	0.4852	ANXA2P2/ANXA2/ARV1/LDLRAP1	4
BP	GO:0032490	detection of molecule of bacterial origin	4/4749	11/18670	0.2987	0.5964	0.4852	TLR4/TLR2/NOD2/TLR6	4
BP	GO:0032908	regulation of transforming growth factor beta1 production	4/4749	11/18670	0.2987	0.5964	0.4852	FURIN/FOXP3/CD2AP/TYROBP	4
BP	GO:0033089	positive regulation of T cell differentiation in thymus	4/4749	11/18670	0.2987	0.5964	0.4852	EGR3/FOXP3/IL7R/VNN1	4
BP	GO:0033327	Leydig cell differentiation	4/4749	11/18670	0.2987	0.5964	0.4852	PLEKHA1/NKX2-1/TMF1/CCND1	4
BP	GO:0033860	regulation of NAD(P)H oxidase activity	4/4749	11/18670	0.2987	0.5964	0.4852	GNAI2/PARK7/CYBA/IL13	4
BP	GO:0035404	histone-serine phosphorylation	4/4749	11/18670	0.2987	0.5964	0.4852	AURKB/AURKA/CCNB1/DRD1	4
BP	GO:0035457	cellular response to interferon-alpha	4/4749	11/18670	0.2987	0.5964	0.4852	IFIT3/AXL/IFIT2/GATA3	4
BP	GO:0035747	natural killer cell chemotaxis	4/4749	11/18670	0.2987	0.5964	0.4852	CCL3/CCL2/CCL7/KLRK1	4
BP	GO:0036462	TRAIL-activated apoptotic signaling pathway	4/4749	11/18670	0.2987	0.5964	0.4852	ATF3/TNFRSF10B/PARK7/TIMP3	4
BP	GO:0039532	negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway	4/4749	11/18670	0.2987	0.5964	0.4852	SEC14L1/NPLOC4/C1QBP/TSPAN6	4
BP	GO:0043117	positive regulation of vascular permeability	4/4749	11/18670	0.2987	0.5964	0.4852	VEGFA/TACR2/TGFB1/PTP4A3	4
BP	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress	4/4749	11/18670	0.2987	0.5964	0.4852	HMOX1/ATF4/EPAS1/SESN2	4
BP	GO:0045060	negative thymic T cell selection	4/4749	11/18670	0.2987	0.5964	0.4852	CD74/PTPRC/CD3E/ZAP70	4
BP	GO:0045176	apical protein localization	4/4749	11/18670	0.2987	0.5964	0.4852	ARF4/SHROOM3/DLG5/GOPC	4
BP	GO:0046950	cellular ketone body metabolic process	4/4749	11/18670	0.2987	0.5964	0.4852	HMGCL/OXCT1/OXCT2/BDH2	4
BP	GO:0048096	chromatin-mediated maintenance of transcription	4/4749	11/18670	0.2987	0.5964	0.4852	PABPC1L/ARID1A/CHEK1/PADI2	4
BP	GO:0048548	regulation of pinocytosis	4/4749	11/18670	0.2987	0.5964	0.4852	AXL/PPT1/STX1B/ACTN4	4
BP	GO:0051024	positive regulation of immunoglobulin secretion	4/4749	11/18670	0.2987	0.5964	0.4852	TNFSF4/GPI/TNFRSF4/HLA-E	4
BP	GO:0051574	positive regulation of histone H3-K9 methylation	4/4749	11/18670	0.2987	0.5964	0.4852	LMNA/ZNF304/DMRTC2/SIRT1	4
BP	GO:0060088	auditory receptor cell stereocilium organization	4/4749	11/18670	0.2987	0.5964	0.4852	MYO7A/TRIOBP/SCRIB/STRC	4
BP	GO:0060992	response to fungicide	4/4749	11/18670	0.2987	0.5964	0.4852	KLF2/KLF4/KDM5B/BCL2L1	4
BP	GO:0061314	Notch signaling involved in heart development	4/4749	11/18670	0.2987	0.5964	0.4852	NOTCH1/SNAI1/RBPJ/JAG1	4
BP	GO:0070203	regulation of establishment of protein localization to telomere	4/4749	11/18670	0.2987	0.5964	0.4852	CCT5/TERF1/WRAP53/CCT3	4
BP	GO:0070933	histone H4 deacetylation	4/4749	11/18670	0.2987	0.5964	0.4852	RCOR1/SIRT2/HDAC9/SIRT7	4
BP	GO:0071688	striated muscle myosin thick filament assembly	4/4749	11/18670	0.2987	0.5964	0.4852	MYBPC3/MYOM1/TCAP/MYBPC2	4
BP	GO:0072070	loop of Henle development	4/4749	11/18670	0.2987	0.5964	0.4852	PKD2/JAG1/UMOD/DLL1	4
BP	GO:0072608	interleukin-10 secretion	4/4749	11/18670	0.2987	0.5964	0.4852	ISG15/LGALS9/TNFRSF21/LILRA5	4
BP	GO:0072711	cellular response to hydroxyurea	4/4749	11/18670	0.2987	0.5964	0.4852	TREX1/TIMELESS/FMR1/DDX11	4
BP	GO:0086023	adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process	4/4749	11/18670	0.2987	0.5964	0.4852	PDE4D/ATP2B4/GNAI2/AKAP13	4
BP	GO:0090193	positive regulation of glomerulus development	4/4749	11/18670	0.2987	0.5964	0.4852	EGR1/CFLAR/ADIPOQ/PDGFB	4
BP	GO:0098883	synapse pruning	4/4749	11/18670	0.2987	0.5964	0.4852	CDK5/C1QB/C1QA/CX3CR1	4
BP	GO:1901096	regulation of autophagosome maturation	4/4749	11/18670	0.2987	0.5964	0.4852	FYCO1/CALCOCO2/UVRAG/PHF23	4
BP	GO:1902221	erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process	4/4749	11/18670	0.2987	0.5964	0.4852	IL4I1/FAH/HGD/GSTZ1	4
BP	GO:1902222	erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process	4/4749	11/18670	0.2987	0.5964	0.4852	IL4I1/FAH/HGD/GSTZ1	4
BP	GO:1902563	regulation of neutrophil activation	4/4749	11/18670	0.2987	0.5964	0.4852	GRN/CD177/BCR/PTAFR	4
BP	GO:1902946	protein localization to early endosome	4/4749	11/18670	0.2987	0.5964	0.4852	SORL1/DTX3L/EZR/SCRIB	4
BP	GO:1905214	regulation of RNA binding	4/4749	11/18670	0.2987	0.5964	0.4852	CARM1/FMR1/EIF3E/NUCKS1	4
BP	GO:1905383	protein localization to presynapse	4/4749	11/18670	0.2987	0.5964	0.4852	DVL1/WNT7A/MAP1A/TERF2	4
BP	GO:2000392	regulation of lamellipodium morphogenesis	4/4749	11/18670	0.2987	0.5964	0.4852	CORO1C/SRC/CORO1B/CD44	4
BP	GO:2000551	regulation of T-helper 2 cell cytokine production	4/4749	11/18670	0.2987	0.5964	0.4852	NLRP3/RSAD2/ARG1/GATA3	4
BP	GO:0048568	embryonic organ development	114/4749	428/18670	0.2993	0.5973	0.4859	MYO7A/TWIST1/LIF/VEGFA/NOTCH1/E2F7/E2F8/STIL/CSF2/MTHFD1L/NR4A3/IL10/SLC39A1/SRF/PDGFA/PHLDA2/PLCD3/PRDM1/PLK4/PTCH1/ST14/TNF/CHRNA10/RPL38/MSX1/VASH1/MICAL2/RNF207/SOCS3/SNAI1/ALX1/CTHRC1/MBD2/GNAS/TGFB3/GTPBP3/FZD6/PTK7/FGF9/RBPJ/PKD2/TMIE/HLX/SPINT1/RUNX2/HOXB7/TIFAB/RAD23B/COL11A1/STK3/WDPCP/TBX6/TRIOBP/IFT122/PCDH12/USH1G/NRK/DVL1/MTHFD1/SCRIB/MKKS/INSIG1/IFT172/ARID1A/POLE/ERCC2/GGNBP2/WDR60/RBPMS2/HS6ST1/WDR19/HOXB2/EPAS1/CITED2/TTC39C/CEBPB/VPS52/IRX5/STRC/SOX11/TFEB/YAP1/KRT19/RARRES2/DNAJB6/ADM/RSPO3/SETDB2/DLX5/ZFP36L1/LRP6/HOXA11/FGF8/BCR/PCSK5/MED12/MYO3B/PBX1/FZD5/DLL1/WDR48/TGFB1/TCAP/RARA/MAPK1/RDH10/SYF2/VAX2/PDGFB/ZFPM1/GATA3/ERCC1/GCM1/GJA5	114
BP	GO:0050678	regulation of epithelial cell proliferation	101/4749	378/18670	0.2995	0.5975	0.4861	VDR/EGR3/IQGAP3/NR4A1/TWIST1/CD109/VEGFA/NOTCH1/NR4A3/PPARG/SULF2/DUSP10/IL10/CDKN2B/LRG1/GRN/UHRF1/CYP7B1/CEACAM1/TP63/PTCH1/HMGB1/TNF/SIRT6/ZFP36/BRCA2/AKT3/BAX/MTOR/GPX1/WNT10B/MMP12/STAT3/VASH1/HMOX1/SFN/CFLAR/FGF9/CCL2/SYNJ2BP/PDCL3/TCF7L2/ZNF304/KDM5B/PRKCA/IFT122/KLF9/TGM1/ATOH8/NOD2/SP1/IFT172/WDR77/IL26/ARG1/FLT1/WNT7A/PPP1R16B/JUN/PEX2/ERBB2/TNFSF12/PTPRM/SOX11/CYBA/NLRC3/YAP1/NRARP/ZNF703/LACRT/FLT4/EGFL7/EMC10/SFRP1/GHRL/IFT80/F3/KRIT1/DLX5/STAT5A/ZFP36L1/NUPR1/EAF2/STAT1/TINF2/PPARD/HTRA1/THBS4/WDR48/ID1/TGFB1/SEMA5A/HAS2/CCND1/PDGFB/ESRP2/GATA3/VEGFC/BAD/NME2/SIRT1	101
BP	GO:0015711	organic anion transport	128/4749	482/18670	0.2999	0.5981	0.4866	IL1B/SLCO4A1/SLC16A3/SLC35A2/PPARG/ADORA2A/NTRK2/ABCC1/SLC1A5/ABCG1/SLC6A6/SLC1A1/SLC7A5/SLC6A8/PPFIA4/SLC16A1/NMB/SFXN1/PCTP/CEACAM1/MFSD2A/ATP11A/PRELID1/ATP8B4/SLC2A8/SLC25A1/NFKBIE/SLC4A2/SLC36A1/CTNS/SLC25A23/LDLR/ABCD1/PITPNA/SLC35B1/SLC43A1/SLC7A5P1/GLS2/SLC4A3/SLC1A4/ABAT/SYT4/SLC52A1/SLC27A2/PLA2G12A/C2CD2L/SLC3A2/SLC25A25/PER2/SLC35D2/MAP2K6/ACSL1/CYB5R2/SLC35D1/PITPNM1/HBA2/CCK/SLC51A/CASR/PRKAB2/SLC52A2/SLC25A14/SLC4A11/SLC35B2/ABCA1/KCNN4/STARD10/TMEM30A/SLCO3A1/SLC26A6/ARG1/SLC4A10/RXRA/BDKRB2/PRKAG2/PPFIA3/NTSR1/SLC38A9/SLC38A2/ABCB4/OCA2/SLC25A5/SLC7A1/PLEKHA8/CA2/ATP10A/CYB5R1/PLIN2/PRAF2/SLC38A6/ATP8B3/ACSL4/SLC33A1/LCN1/SLC16A6/SLC36A4/ATP10D/CPT1A/PLA2G2A/SLC16A10/HBB/PLA2G2C/SLC27A4/SLC2A14/ACACB/SLC23A2/SLC25A42/SLC6A20/CETP/TNFAIP8L3/LRRC8D/CA4/CYB5RL/SLC35B4/SLC25A4/GLTPD2/ATP11C/TNFSF11/PLA2G5/PPARD/MPC1/CA13/SV2A/PLEKHA3/SLCO4C1/SLC22A25/P2RX7/NCOR1	128
BP	GO:0046890	regulation of lipid biosynthetic process	54/4749	198/18670	0.3002	0.5984	0.4869	VDR/EGR1/IL1B/ABCG1/PDGFA/TREX1/CEACAM1/TNF/MTOR/LDLR/ABCD1/PMVK/FDPS/TSPO/FITM2/SCD/SNAI1/ABCD2/FABP5/HTR2A/CD74/ENHO/PRKAB2/ADIPOR2/SLC45A3/INSIG1/SP1/ADIPOR1/PRKAG2/FPR2/CYP27B1/AGAP2/PIBF1/DDX20/RAB38/SQLE/CREBL2/ADM/ADIPOQ/POR/DGAT2/ORMDL2/ACACB/FASN/MBTPS2/SPHK2/CYP7A1/RDH10/PDGFB/SREBF2/ORMDL3/NFYB/TRIB3/SIRT1	54
BP	GO:0046661	male sex differentiation	44/4749	160/18670	0.301	0.6	0.4881	ASPM/ICAM1/NTRK1/KIF18A/BAX/NASP/PLEKHA1/NUDT1/NKX2-1/RRM1/RAB13/UBB/ARID5B/FGF9/BIK/SDC1/PATZ1/TBC1D20/GREB1L/FNDC3A/SOX8/NCOA4/REC8/CITED2/BCL2L1/ADAM15/CTNNA1/RBMY1B/SFRP1/ESR1/KDM5A/TNFSF10/HOXA11/INSR/NUPR1/FGF8/ARID4A/WDR48/ASB1/TMF1/RARA/CCND1/GATA3/ERCC1	44
BP	GO:0009746	response to hexose	55/4749	202/18670	0.3029	0.6036	0.491	EGR1/TXNIP/ICAM1/SRF/RAC1/LDHA/PIM3/COL6A2/SMARCB1/TIAM1/ARRB1/ENY2/C2CD2L/SRI/IGF1R/EIF2B3/GJD3/LGALS1/CASR/TCF7L2/SMARCA4/NAMPT/TRPM4/NADK/OXCT1/PFKFB2/LRP1/SLC26A6/ACVR1C/ACVR2B/PRKCE/SIDT2/LRP5L/ZNF236/CYBA/BRSK2/NDUFA9/GHRL/ADIPOQ/ERN1/RAB11FIP5/GCLC/PFKL/PPARD/SLC9B2/CYP7A1/ATG7/TGFB1/NDUFAF2/SESN2/PDX1/GIPR/SYBU/BAD/NME2	55
BP	GO:0045667	regulation of osteoblast differentiation	35/4749	126/18670	0.3033	0.6041	0.4914	TWIST1/NOTCH1/RASSF2/TP63/PTCH1/TNF/SKI/ESRRA/WNT10B/CLIC1/NBR1/FBXO5/CTHRC1/LIMD1/GNAS/FAM20C/SMAD6/RUNX2/PDLIM7/JAG1/ATRAID/TRPM4/IFITM1/ACVR2B/CEBPB/SOX11/SMAD1/SFRP1/SUCO/SEMA4D/AXIN2/TMEM119/ID1/TMEM64/ILK	35
BP	GO:0001954	positive regulation of cell-matrix adhesion	15/4749	51/18670	0.3046	0.6062	0.4932	VEGFA/SDC4/RAC1/CSF1/NINJ1/LIMS1/PLEKHA2/S100A10/THY1/EPB41L5/CD3E/SFRP1/UTRN/FMN1/ILK	15
BP	GO:0009994	oocyte differentiation	15/4749	51/18670	0.3046	0.6062	0.4932	AURKA/TRIP13/PPP2R1A/BRCA2/CCNB1/FBXO5/PABPC1L/DMC1/FIGLA/REC8/SIRT2/TDRD5/SOHLH1/ATM/CDC25B	15
BP	GO:0032206	positive regulation of telomere maintenance	15/4749	51/18670	0.3046	0.6062	0.4932	AURKB/NEK2/PML/SIRT6/CCT5/TNKS2/ACD/GNL3/POT1/ATR/ATM/MAPK1/ERCC1/FBXO4/CCT3	15
BP	GO:0000303	response to superoxide	9/4749	29/18670	0.3066	0.6079	0.4946	TNF/NQO1/DHFR/FANCC/PARK7/MPO/CCS/ADPRHL2/PRDX1	9
BP	GO:0007271	synaptic transmission, cholinergic	9/4749	29/18670	0.3066	0.6079	0.4946	ADORA2A/CHRNA10/CHRNA5/RIC3/NQO1/CHRNA1/TACR2/CHRNA3/CHRNG	9
BP	GO:0031114	regulation of microtubule depolymerization	9/4749	29/18670	0.3066	0.6079	0.4946	CKAP2/ARHGEF2/FGF13/CLASP2/MID1/MAP1S/TRIM54/MAP1A/APC	9
BP	GO:0033032	regulation of myeloid cell apoptotic process	9/4749	29/18670	0.3066	0.6079	0.4946	IRF7/THRA/CCR5/CDKN2A/NOD2/MAEA/ADIPOQ/CLEC5A/SIRT1	9
BP	GO:0042219	cellular modified amino acid catabolic process	9/4749	29/18670	0.3066	0.6079	0.4946	CHAC1/ABHD16A/CHAC2/GGT1/MTHFS/SARDH/BHMT/GGTLC2/GGT7	9
BP	GO:0048261	negative regulation of receptor-mediated endocytosis	9/4749	29/18670	0.3066	0.6079	0.4946	RAC1/SDCBP/UNC119/LRPAP1/SYT11/RABGEF1/UBQLN2/ARF6/DLG4	9
BP	GO:0050855	regulation of B cell receptor signaling pathway	9/4749	29/18670	0.3066	0.6079	0.4946	CBFB/BLK/GCSAM/NFAM1/PLCL2/CD19/PRKCB/GCSAML/SLC39A10	9
BP	GO:0050974	detection of mechanical stimulus involved in sensory perception	9/4749	29/18670	0.3066	0.6079	0.4946	ITGA2/NTRK1/CHRNA10/HTR2A/COL11A1/MKKS/STRC/TMC2/FYN	9
BP	GO:0055075	potassium ion homeostasis	9/4749	29/18670	0.3066	0.6079	0.4946	SLC12A4/SLC12A2/KCNJ2/ATP1B1/TFAP2B/ATP1B3/KCNH2/SLC12A6/SLC12A5	9
BP	GO:0060142	regulation of syncytium formation by plasma membrane fusion	9/4749	29/18670	0.3066	0.6079	0.4946	CAMK1/CXCL10/IL4R/CFLAR/CXCL9/FLOT1/TYROBP/ADAM9/GCM1	9
BP	GO:0072606	interleukin-8 secretion	9/4749	29/18670	0.3066	0.6079	0.4946	LGALS9/FFAR2/FCN1/TLR2/CD58/TLR6/ANXA4/F2R/RAB1A	9
BP	GO:2000765	regulation of cytoplasmic translation	9/4749	29/18670	0.3066	0.6079	0.4946	ZNF385A/MTOR/DPH5/DPH1/CNBP/FMR1/DNAJC24/CPEB1/UNK	9
BP	GO:0032008	positive regulation of TOR signaling	12/4749	40/18670	0.3072	0.6081	0.4947	SEC13/AKT3/SIK3/WDR24/SLC38A9/HTR6/LAMTOR4/LAMTOR2/KLHL22/RRAGB/SEH1L/MLST8	12
BP	GO:0035735	intraciliary transport involved in cilium assembly	12/4749	40/18670	0.3072	0.6081	0.4947	WDR34/DYNLRB1/IFT122/IFT172/KIF3C/IFT27/WDR60/WDR19/IFT80/TTC26/CLUAP1/TNPO1	12
BP	GO:0090184	positive regulation of kidney development	12/4749	40/18670	0.3072	0.6081	0.4947	EGR1/LIF/VEGFA/PDGFA/CFLAR/HOXB7/SOX8/BASP1/ADIPOQ/TGFB1/PDGFB/GATA3	12
BP	GO:0098760	response to interleukin-7	12/4749	40/18670	0.3072	0.6081	0.4947	SOCS2/STAT3/STIP1/BTK/IL2RG/SMARCA4/RAD23B/IL7R/IL7/STAT5A/JAK3/JAK1	12
BP	GO:0098761	cellular response to interleukin-7	12/4749	40/18670	0.3072	0.6081	0.4947	SOCS2/STAT3/STIP1/BTK/IL2RG/SMARCA4/RAD23B/IL7R/IL7/STAT5A/JAK3/JAK1	12
BP	GO:0040014	regulation of multicellular organism growth	19/4749	66/18670	0.3079	0.6087	0.4952	PLAC8/BBS2/PTCH1/SOCS2/GAMT/CSF1/STAT3/FXN/PLS1/MBD5/EZR/TNKS2/MKKS/CACNA2D2/SH3PXD2B/GHRL/GPR21/STAT5A/ATRN	19
BP	GO:0046626	regulation of insulin receptor signaling pathway	19/4749	66/18670	0.3079	0.6087	0.4952	IL1B/MZB1/SOCS2/PTPN1/SORL1/SRC/SOCS3/PAK1/ENHO/FFAR3/ADIPOR1/SLA2/GNAI2/GSK3A/GPR21/PRKCB/NUCKS1/GKAP1/SIRT1	19
BP	GO:0048207	vesicle targeting, rough ER to cis-Golgi	19/4749	66/18670	0.3079	0.6087	0.4952	SEC13/GORASP1/SEC24D/MCFD2/F5/STX5/SEC16A/CNIH2/ANKRD28/TBC1D20/TMED10/CTSZ/TRAPPC4/RAB1A/PPP6C/PEF1/PPP6R1/RAB1B/USO1	19
BP	GO:0048208	COPII vesicle coating	19/4749	66/18670	0.3079	0.6087	0.4952	SEC13/GORASP1/SEC24D/MCFD2/F5/STX5/SEC16A/CNIH2/ANKRD28/TBC1D20/TMED10/CTSZ/TRAPPC4/RAB1A/PPP6C/PEF1/PPP6R1/RAB1B/USO1	19
BP	GO:0001510	RNA methylation	23/4749	81/18670	0.3084	0.6095	0.4959	TRMT12/GTPBP3/ALKBH8/NSUN4/TRMT1/NSUN5P1/TARBP1/NSUN6/TRMT10B/TRMT13/TRMT112/METTL8/EMG1/TRMT2A/FBL/FDXACB1/RRNAD1/METTL16/ZCCHC4/TRMT10C/TRMT1L/TFB2M/NSUN2	23
BP	GO:0034248	regulation of cellular amide metabolic process	128/4749	483/18670	0.3094	0.6112	0.4972	ITGA2/LARP4/ABCG1/PDPR/BCL3/GAPDH/CYFIP1/ZNF385A/CTSA/PGAM1/TYMS/EIF4EBP1/TNF/ZFP36/ZC3H12D/PLEKHN1/MTOR/RPL38/POLDIP3/KLHL25/STAT3/SORL1/DPH5/RPL5/RPL26/ATP13A2/CLU/TNRC6B/PAIP2B/EIF5B/ATF4/PER2/CTIF/RPS3/NSUN4/CIRBP/UPF1/ZFP36L2/DHFR/PINK1/FASTKD2/ZNF598/DPH1/PA2G4/CNOT3/CNBP/COA3/NCL/TRNAU1AP/MEX3D/RPS9/EIF4H/NOLC1/RBM4B/RXRA/EEF1A1/TRUB2/RBM23/MKNK1/FMR1/ACO1/SPON1/ERBB2/TMED10/RPS4X/ZC3H12A/VIM/EEF1A2/MRPL13/MTG1/GSK3A/UPF3A/ELAVL1/CNOT7/YTHDF3/EIF3H/EIF2S3/PTCD3/FASTKD3/MAGOH/DAPK1/METTL16/IFNGR1/EIF2AK3/OGFOD1/SAMD4B/GIGYF2/EIF4E2/LRPPRC/ZCCHC4/ILF3/DNAJC24/PRNP/MIF4GD/UHMK1/PRR16/RNF139/ORMDL2/TRMT10C/SERP1/ZFP36L1/CPEB1/GLE1/C1QBP/EIF4E3/SPHK2/ZNF540/PPP1R15A/NGRN/MIR181D/EIF3E/RBM3/NCBP2/SECISBP2L/GUF1/RARA/MAPK1/GSTZ1/GEMIN5/UNK/SESN2/PTAFR/KHSRP/ORMDL3/RPL22/NGDN/MALSU1/PIWIL4	128
BP	GO:0070838	divalent metal ion transport	128/4749	483/18670	0.3094	0.6112	0.4972	VDR/GEM/ICAM1/ADORA2A/SLC39A1/HSPA2/PTPN6/CCR1/SESTD1/ORAI2/CDK5/ANXA2P2/LGALS3/SLC39A7/YWHAE/CHERP/PML/NIPAL4/TSPAN13/CDH23/JSRP1/CHRNA10/NCS1/NOL3/BAX/CXCL10/TRPC1/LILRA2/SLC25A23/ANXA2/HOMER2/TSPO/MYO5A/HCRT/REM1/P2RX1/HOMER1/PDE4D/HTR2A/ATP2A1/CCL3/CAMK2A/KCNE3/PDE4B/SRI/MICU1/CD33/CYSLTR1/KCNJ2/SLC3A2/PKD2/SLC25A25/CCR5/HTT/CCL2/SLC39A11/PARL/GPR35/ATP1B1/CASR/GSTO1/TPCN1/PTPRC/CNNM4/REM2/CORO1A/TRPM4/RASA3/ANXA5/CACNG3/STAC3/ORAI3/CXCL9/KCNN4/BAK1/DRD1/LILRB2/FKBP1A/ATP2B4/STAC/DDIT3/THY1/CD19/CACNA2D2/SUMO1/GNAI2/NTSR1/SLC24A3/VDAC1/CYP27B1/FMR1/CAMK2G/PRKCE/CUL5/GRIN3B/CYBA/LILRA5/LACRT/IL13/SLC41A2/CAMK2D/P2RX5/PRNP/ISCU/F2R/CSN2/EPB41/PRKCB/TRPC7/AHNAK/SPHK2/CACNB2/TMC2/CATSPER2/EHD3/CLCA1/FFAR1/PLCB1/SLC39A10/TGFB1/NMUR1/TRPC5/SPG7/PDGFB/SLC40A1/P2RX7/SLC35G1/FYN	128
BP	GO:0010927	cellular component assembly involved in morphogenesis	32/4749	115/18670	0.31	0.6121	0.498	SRF/GPC1/CD9/RFX2/MYH10/ACTG1/TMOD2/CFLAR/CCDC136/PIKFYVE/TBC1D20/MPP5/CLASP2/TLR2/MYBPC3/ERCC2/NRAP/WDR1/KRT19/PMP22/PHLDB1/MYOM1/OBSCN/DICER1/BMP10/TPM1/AKAP13/MYH6/TCAP/TMF1/MYBPC2/ILK	32
BP	GO:0046683	response to organophosphorus	37/4749	134/18670	0.311	0.614	0.4995	IL1B/FOSL1/LDHA/FOSB/TYMS/HSPA5/WNT10B/PPARGC1B/P2RX1/P2RY11/PDXP/HCN2/P2RX6/PKD2/SDC1/CARM1/EZR/TRPM4/SLC26A6/RAPGEF1/JUN/BSG/RAPGEF2/ALDH3A1/ADIPOQ/P2RX5/AANAT/ZFP36L1/P2RY1/STAT1/PLA2G5/FOS/TRIM16/PTAFR/P2RX7/CRLS1/DUSP1	37
CC	GO:0005819	spindle	144/4919	347/19717	7.047e-12	5.419e-09	4.399e-09	KIF20A/ESPL1/CENPF/CRMP1/CKAP2L/AURKB/CDCA8/GPSM2/TPX2/KIF14/SKA1/KIFC1/ASPM/KIF4A/BUB1B/FAM83D/GEM/TTK/KIF15/CDK1/SHCBP1/BIRC5/AURKA/KIF23/NEDD9/HSPA2/WDR62/KIF20B/NEK2/CDC20/DLGAP5/SKA3/NUSAP1/EML4/TACC3/SPAG5/RACGAP1/FAM110A/KIF18A/CDC6/SAC3D1/SMC3/MYH10/INCENP/PLK2/ODF2/CTTN/KIF11/PLK1/UXT/CKAP2/PSRC1/NR3C1/CCNB1/MAPRE2/CENPE/FBXO5/MZT2A/NUMA1/CAPG/ARHGEF2/KAT2A/FAM110C/PKD2/BOD1/TOPBP1/POC1A/UNC119/RPS3/PPP2R3C/TERF1/TUBGCP2/STX1B/CYLD/CLASP2/NUDCD2/PKP4/KLHL21/PPP2CA/CEP19/TUBG2/SBDS/MID1/MAEA/MZT2B/BRCC3/EMD/INVS/ERCC2/MAP1S/WDR73/SLC25A5/TOPORS/WDR60/RAE1/ECT2/PRC1/BEX4/MICAL3/ALMS1/PRPF19/HAUS5/AUNIP/DDX11/SIRT2/KATNAL2/CDC14B/MYH9/ARL2BP/RAB11FIP4/NSFL1C/TUBG1/UMOD/MAD2L2/CCDC69/CENPV/KATNBL1/KLHL22/TBCK/SMC1A/CHAMP1/MAP9/EFHC1/ARL3/ATM/AAAS/CEP44/TMEM201/NSUN2/PIN4/CDC42/TTC28/CEP89/CDC25B/TUBGCP5/MAPK1/DIDO1/NUP62/CDC16/NCOR1/CKAP5/SPIN1/SPECC1L/TUBGCP3	144
CC	GO:0044391	ribosomal subunit	88/4919	190/19717	1.17e-10	4.498e-08	3.651e-08	LARP4/RPL3/MRPL37/MRPL28/RPS8/RPL32/RPS25/RPS12/RPL10A/RPS18/RPS27/MRPL51/MRPS36/RPL35/RPL38/RPS10/RPS3A/RPLP2/RPL21/MRPL22/RPL19/RPL23A/RPS5/RPL36/RPL5/RPL4/RPL30/MRPL18/RPL27A/RPL26/MRPS5/RPS23/RPS6/RPS15/MRPS18C/RPL36A/MRPS11/RPL7/RPL18A/RPS13/RPS20/RPL6/RPS3/NSUN4/RPS15A/HBA2/C12orf65/RPS27A/MRPS6/RPL23/RPS11/RPS19/UBA52/RPS16/MRPL20/RPS9/RPL14/MRPL50/RPL37A/MRPL36/MRPS2/RPL37/MRPL35/MRPL27/MRPL15/RPL29/MRPL34/RPS4X/RPL12/MRPS14/MRPL13/RPSA/EIF2D/RPS28/MRPL10/RPL7A/RPL39/MRPL54/DAP3/MRPL2/RPL11/MRPL39/RBM3/GEMIN5/MRPL43/RPL22/MRPL48/MALSU1	88
CC	GO:0030496	midbody	81/4919	173/19717	3.291e-10	8.436e-08	6.848e-08	KIF20A/CENPF/CRMP1/AURKB/CDCA8/KIF14/ANLN/ASPM/KIF4A/GEM/CDK1/SHCBP1/BIRC5/AURKA/KIF23/CIT/CEP55/MICAL1/KIF20B/NEK2/LAP3/BCL3/RASGEF1B/SPAG5/RACGAP1/PTCH1/MYH10/HSPA5/INCENP/SVIL/PLK1/ANXA2/PSRC1/ERH/CENPE/CAPG/PDXP/MPLKIP/MBD5/PITPNM1/KLHL9/CYLD/TRIOBP/PKP4/CCDC124/RALA/DTNBP1/RNF8/GNAI2/RAB11FIP3/TOPORS/MARK4/ECT2/PRC1/C6orf89/IST1/UVRAG/MICAL3/CLIC4/DDX11/PIK3C3/SIRT2/ARL2BP/RAB11FIP4/CCDC69/ARF6/TBCK/TTC19/CHAMP1/RALB/ARL3/CEP44/MITD1/WIZ/ALKBH4/CDC42/TTC28/NUP62/GDI1/KLHL13/KLHDC8B	81
CC	GO:0022626	cytosolic ribosome	58/4919	112/19717	9.131e-10	1.755e-07	1.425e-07	LARP4/RPL3/RPS8/RPL32/RPS25/RPS12/RPL10A/RPS18/RPS27/RPL35/RPL38/RPS10/RPS3A/RPLP2/RPL21/RPL19/RPL23A/RPS5/RPL36/RPL5/RPL4/RPL30/RPL27A/RPL26/RPS23/RPS6/RPS15/RPL36A/RPL7/RPL18A/RPS13/RPS20/RPL6/RPS3/RPS15A/HBA2/RPS27A/RPL23/RPS11/RPS19/UBA52/RPS16/RPS9/RPL14/RPL37A/RPL37/RPL29/RPS4X/RPL12/RPSA/EIF2D/EIF2AK3/RPS28/RPL7A/RPL39/RPL11/GEMIN5/RPL22	58
CC	GO:0005924	cell-substrate adherens junction	154/4919	408/19717	5.119e-09	6.867e-07	5.574e-07	PLEC/MCAM/LAYN/SDC4/ITGA2/ICAM1/ITGA3/KIF23/NEDD9/FES/MARCKS/HCK/RAC1/SNTB1/LAP3/PLAUR/CYFIP1/ZYX/RPL3/TGFB1I1/CORO1C/YWHAE/CD9/YWHAZ/RPS8/HSPA5/PPP1CB/ARMC5/GSN/HSPA1A/SLC4A2/CTTN/SVIL/RPL10A/PLAU/RPS18/TLE2/NHS/ITGB8/RPL38/CAPN1/RPS10/RPS3A/RPLP2/ACTG1/RPL19/CDC42EP1/RPS5/MAPRE2/RPL5/RPL4/RPL30/TGM2/RHOG/ARHGEF2/LIMD1/LMLN/HSPA9/TRIP6/CORO1B/FBLN7/PAK4/RPS15/SDCBP/ARHGAP31/RPL7/PAK1/RPS13/PTK7/RPL6/APBB1IP/LIMS1/RPS3/ATP6V0C/ARPC1B/PDLIM7/CAPN5/RPL23/RPS11/PTPRC/RPS19/EZR/CLASP2/ITGA1/VASP/TRIOBP/ANXA5/TNS3/L1CAM/CFL1/PARVB/ITGA6/ACTN4/FLOT1/RPS16/ARPC5/RPS9/LRP1/SNAP23/RALA/LIMK1/THY1/FLT1/XIRP2/RPL37A/YWHAQ/CD46/CHP1/ABCB4/EPB41L5/NRAP/CD44/RAC2/AFAP1/CD151/STX16/RPS4X/EPB41L2/CD99L2/CYBA/RPL12/VIM/TSPAN4/BSG/CTNNA1/RHOU/MDC1/MYH9/RPL7A/ITGA2B/CNN2/ARF6/AHNAK/AIF1L/ARL2/SORBS3/ARHGAP24/LASP1/EHD3/PIP5K1A/CDC42/UBOX5/PPP1R12A/MAPK1/SLC9A3R2/ADAM9/SYNE2/TADA1/RPL22/RRAS2/ILK/JAK1/ARL14EP/ACTB	154
CC	GO:0005925	focal adhesion	153/4919	405/19717	5.358e-09	6.867e-07	5.574e-07	PLEC/MCAM/LAYN/SDC4/ITGA2/ICAM1/ITGA3/KIF23/NEDD9/FES/MARCKS/HCK/RAC1/SNTB1/LAP3/PLAUR/CYFIP1/ZYX/RPL3/TGFB1I1/CORO1C/YWHAE/CD9/YWHAZ/RPS8/HSPA5/PPP1CB/ARMC5/GSN/HSPA1A/SLC4A2/CTTN/SVIL/RPL10A/PLAU/RPS18/TLE2/NHS/ITGB8/RPL38/CAPN1/RPS10/RPS3A/RPLP2/ACTG1/RPL19/CDC42EP1/RPS5/MAPRE2/RPL5/RPL4/RPL30/TGM2/RHOG/ARHGEF2/LIMD1/LMLN/HSPA9/TRIP6/CORO1B/FBLN7/PAK4/RPS15/SDCBP/ARHGAP31/RPL7/PAK1/RPS13/PTK7/RPL6/APBB1IP/LIMS1/RPS3/ATP6V0C/ARPC1B/PDLIM7/CAPN5/RPL23/RPS11/PTPRC/RPS19/EZR/CLASP2/ITGA1/VASP/TRIOBP/ANXA5/TNS3/L1CAM/CFL1/PARVB/ITGA6/ACTN4/FLOT1/RPS16/ARPC5/RPS9/LRP1/SNAP23/RALA/LIMK1/THY1/FLT1/XIRP2/RPL37A/YWHAQ/CD46/CHP1/ABCB4/EPB41L5/CD44/RAC2/AFAP1/CD151/STX16/RPS4X/EPB41L2/CD99L2/CYBA/RPL12/VIM/TSPAN4/BSG/CTNNA1/RHOU/MDC1/MYH9/RPL7A/ITGA2B/CNN2/ARF6/AHNAK/AIF1L/ARL2/SORBS3/ARHGAP24/LASP1/EHD3/PIP5K1A/CDC42/UBOX5/PPP1R12A/MAPK1/SLC9A3R2/ADAM9/SYNE2/TADA1/RPL22/RRAS2/ILK/JAK1/ARL14EP/ACTB	153
CC	GO:0030055	cell-substrate junction	154/4919	412/19717	1.1e-08	1.209e-06	9.813e-07	PLEC/MCAM/LAYN/SDC4/ITGA2/ICAM1/ITGA3/KIF23/NEDD9/FES/MARCKS/HCK/RAC1/SNTB1/LAP3/PLAUR/CYFIP1/ZYX/RPL3/TGFB1I1/CORO1C/YWHAE/CD9/YWHAZ/RPS8/HSPA5/PPP1CB/ARMC5/GSN/HSPA1A/SLC4A2/CTTN/SVIL/RPL10A/PLAU/RPS18/TLE2/NHS/ITGB8/RPL38/CAPN1/RPS10/RPS3A/RPLP2/ACTG1/RPL19/CDC42EP1/RPS5/MAPRE2/RPL5/RPL4/RPL30/TGM2/RHOG/ARHGEF2/LIMD1/LMLN/HSPA9/TRIP6/CORO1B/FBLN7/PAK4/RPS15/SDCBP/ARHGAP31/RPL7/PAK1/RPS13/PTK7/RPL6/APBB1IP/LIMS1/RPS3/ATP6V0C/ARPC1B/PDLIM7/CAPN5/RPL23/RPS11/PTPRC/RPS19/EZR/CLASP2/ITGA1/VASP/TRIOBP/ANXA5/TNS3/L1CAM/CFL1/PARVB/ITGA6/ACTN4/FLOT1/RPS16/ARPC5/RPS9/LRP1/SNAP23/RALA/LIMK1/THY1/FLT1/XIRP2/RPL37A/YWHAQ/CD46/CHP1/ABCB4/EPB41L5/NRAP/CD44/RAC2/AFAP1/CD151/STX16/RPS4X/EPB41L2/CD99L2/CYBA/RPL12/VIM/TSPAN4/BSG/CTNNA1/RHOU/MDC1/MYH9/RPL7A/ITGA2B/CNN2/ARF6/AHNAK/AIF1L/ARL2/SORBS3/ARHGAP24/LASP1/EHD3/PIP5K1A/CDC42/UBOX5/PPP1R12A/MAPK1/SLC9A3R2/ADAM9/SYNE2/TADA1/RPL22/RRAS2/ILK/JAK1/ARL14EP/ACTB	154
CC	GO:0005759	mitochondrial matrix	168/4919	469/19717	7.461e-08	7.172e-06	5.821e-06	PPIF/MTHFD2/CDK1/MTHFD1L/SUOX/TOP3A/PDPR/SCO2/MRPL37/MRPL28/ACSM3/TYMS/ACOT11/MPG/FDXR/MRPL51/ETHE1/MRPS36/PPTC7/GPX1/RAD51/BCKDK/MRPL22/THEM5/MPST/NR3C1/FXN/CCNB1/TST/DTYMK/MMAB/MECR/LDHAL6B/NUDT1/PRDX3/GLS2/MRPL18/ABAT/HSPA9/MRPS5/GLDC/OGDH/MRPS18C/BLOC1S1/MRPS11/MCAT/PDHB/IBA57/LRRC59/MTHFS/SARDH/HMGCL/ALDH2/PRDX5/RPS3/NSUN4/PDHX/NARS2/AK3/NDUFB8/C12orf65/MDH2/NME4/DNAJA3/MRPS6/HSD17B8/ABCE1/LIAS/FASTKD2/TMLHE/OXCT1/OXCT2/DLST/ACP6/FASTK/MRPL20/NDUFS1/DLAT/GRPEL1/PUS1/SIRT3/MRPL50/STYXL1/MRPL36/MRPS2/PPA2/NDUFS7/NAGS/VDAC1/TRUB2/MRPL35/PARK7/MRPL27/YARS2/MRPL15/CS/ETFA/ATAD3A/SLC25A5/TRIT1/NAT8L/AK4/MRPL34/BCL2L1/LARS2/GLUD1/MARS2/MRPS14/MRPL13/MTG1/NDUFA9/IDH3B/CHPF/DNA2/MIPEP/LRPPRC/ME3/GADD45GIP1/ARL2BP/POLG2/SSBP1/MRPL10/ISCU/HARS2/DHRS2/TRMT10C/HSPA1L/MRPL54/ETFB/HIBADH/DAP3/C1QBP/ACSS1/PCCB/PAM16/GPT2/MRPL2/TBRG4/ALDH7A1/AMT/ECI1/GSTK1/TP53AIP1/D2HGDH/ADPRHL2/ARL2/NFS1/ISCA2/MRPL39/CYP11A1/TFB2M/TXNRD2/PPM1K/PIN4/ALDH5A1/GUF1/HADHB/GSTZ1/NMNAT3/NUDT13/MRPL43/ADHFE1/TUFM/TRNT1/SHC1/MRPL48/MALSU1/GFM1	168
CC	GO:0044445	cytosolic part	99/4919	247/19717	1.018e-07	8.698e-06	7.061e-06	NLRP3/CASP9/LARP4/RPL3/ENO1/PFKP/EIF4EBP1/RPS8/RPL32/RPS25/RPS12/NCS1/RPL10A/RPS18/RPS27/MTOR/RPL35/RPL38/RPS10/RPS3A/IFIT5/RPLP2/RPL21/RPL19/RPL23A/FXN/RPS5/RPL36/BLOC1S6/RPL5/RPL4/RPL30/RPL27A/HOMER1/RPL26/CFLAR/RPS23/RPS6/SNAP47/RPS15/RRM1/CTU1/RPL36A/BLOC1S1/RPL7/BCAS4/PSMD1/PSMD2/RPL18A/RPS13/RPS20/RPL6/RPS3/HTT/RPS15A/BLOC1S4/HBA2/RPS27A/CCT5/STXBP5/HPS4/SGTA/RPL23/RPS11/RPS19/UBA52/RPS16/RPS9/PI4K2A/DTNBP1/ENO3/RPL14/STX12/DHX33/RPL37A/RPL37/RPL29/RPS4X/RPL12/HBG1/RPSA/EIF2D/RRM2/SNAPIN/EIF2AK3/RPS28/HBB/RPL7A/RPL39/PRKCB/RPL11/CARD8/PFKL/GEMIN5/PSMC5/RPL22/TRIM9/CCT3/UBL4A	99
CC	GO:0098852	lytic vacuole membrane	131/4919	355/19717	3.099e-07	2.193e-05	1.78e-05	MYO7A/ANPEP/ACPP/CD68/FPR1/SEC13/TLR8/GRN/ATP6V0D1/SURF4/CTSA/HPSE/ATP11A/BRI3/SLC2A8/TM9SF1/NEU1/HLA-DQB2/SLC36A1/AP5S1/CTNS/UBXN6/MTOR/ANXA2/LDLR/HLA-DMA/ABCD1/SLC12A4/TMEM150C/CCZ1/ITFG2/HLA-H/TMEM63A/DTX3L/ARRB1/ATP13A2/BLOC1S1/CD1B/BST2/VPS33B/ATP6V1E1/CD74/RAB3D/SNAP29/CD1D/COL6A1/ATP6V0C/SLC39A11/M6PR/TPCN1/HLA-DPA1/WDR24/ATRAID/PIGR/NFAM1/C12orf66/TMEM106B/ATP6V1A/UBA52/HLA-DRA/AP3D1/FLOT1/PRCP/AP1S1/TOM1/LITAF/PI4K2A/AP2S1/IFITM3/LRP1/TRIM23/GBA/CTSD/TMEM30A/TMEM175/VASN/PLEKHM1/EEF1A1/SLC38A9/C3AR1/OCA2/CUBN/GPR137B/WDR11/KIAA1324/SIDT2/GNB4/HLA-DMB/SLC29A3/EEF1A2/ABCA5/HLA-DQA2/CKAP4/TM6SF1/RDH14/SNAPIN/ATP6V1G1/NPRL3/LAMP1/RAB2A/VTI1B/SYNGR1/GLIPR1/CYBRD1/GOPC/LAMTOR4/ITM2C/LNPEP/HLA-DPB1/LAMTOR2/GNAQ/AHNAK/SPHK2/LMBRD1/NAPG/RAB37/VNN1/ATP11C/LAPTM4A/MANBA/VPS39/STOM/CLCN5/RRAGB/MFSD12/DRAM1/SLCO4C1/HLA-DRB1/SEH1L/RAB12/NPRL2	131
CC	GO:0022627	cytosolic small ribosomal subunit	27/4919	44/19717	3.3e-07	2.193e-05	1.78e-05	LARP4/RPS8/RPS25/RPS12/RPS18/RPS27/RPS10/RPS3A/RPS5/RPS23/RPS6/RPS15/RPS13/RPS20/RPS3/RPS15A/HBA2/RPS27A/RPS11/RPS19/UBA52/RPS16/RPS9/RPS4X/RPSA/EIF2D/RPS28	27
CC	GO:0098687	chromosomal region	129/4919	349/19717	3.423e-07	2.193e-05	1.78e-05	CENPF/AURKB/KIF2C/CDCA8/CENPA/SKA1/HJURP/CDCA5/BUB1B/NCAPG/TTK/PMF1/CDK1/CDT1/BIRC5/ZWINT/AURKA/CENPM/RASSF2/DOT1L/NEK2/SEC13/ESCO2/SKA3/MCM4/SPC25/ERCC6L/BUB1/SPC24/SPAG5/MCM5/NCAPD2/KIF18A/PPP2R1A/PML/SMC3/CENPW/NUF2/INCENP/SIRT6/PPP1CB/NUP98/BRCA2/PLK1/FEN1/RAD51/ZNF276/CCNB1/MCM2/CBX5/SNAI1/CENPE/NDC80/TP53BP1/PIF1/CDK2/CENPT/DMC1/ORC1/ZNFX1/SUMO3/CENPO/BOD1/XRCC6/MBD6/SUN2/MBD5/DCTN5/UPF1/MCM7/TERF1/CLASP2/DSCC1/EID3/TFIP11/EZH2/NUDCD2/TNKS2/CENPI/PPP2CA/TOX4/ACD/CTC1/THOC3/RNF8/CENPP/CENPN/FMR1/MCM3/REC8/CHEK1/CEBPB/RECQL4/HELLS/UVRAG/OIP5/STAG3/POT1/XRCC3/XRCC1/FBXO28/WRAP53/SIRT2/DNA2/SMG6/ATR/CHEK2/CENPV/WDR82/APC/SMC1A/CHAMP1/TINF2/SIRT7/ATM/WRN/SMC5/KDM4C/ORC2/PPP1R12A/TRAPPC12/LRWD1/SEH1L/ERCC1/CKAP5/NGDN/ZBTB48/CENPK/TERF2	129
CC	GO:0005765	lysosomal membrane	130/4919	354/19717	4.667e-07	2.595e-05	2.106e-05	MYO7A/ANPEP/ACPP/CD68/FPR1/SEC13/TLR8/GRN/ATP6V0D1/SURF4/CTSA/HPSE/ATP11A/BRI3/SLC2A8/TM9SF1/NEU1/HLA-DQB2/SLC36A1/AP5S1/CTNS/UBXN6/MTOR/ANXA2/LDLR/HLA-DMA/ABCD1/SLC12A4/TMEM150C/CCZ1/ITFG2/HLA-H/TMEM63A/DTX3L/ARRB1/ATP13A2/BLOC1S1/CD1B/BST2/VPS33B/ATP6V1E1/CD74/RAB3D/SNAP29/CD1D/COL6A1/ATP6V0C/M6PR/TPCN1/HLA-DPA1/WDR24/ATRAID/PIGR/NFAM1/C12orf66/TMEM106B/ATP6V1A/UBA52/HLA-DRA/AP3D1/FLOT1/PRCP/AP1S1/TOM1/LITAF/PI4K2A/AP2S1/IFITM3/LRP1/TRIM23/GBA/CTSD/TMEM30A/TMEM175/VASN/PLEKHM1/EEF1A1/SLC38A9/C3AR1/OCA2/CUBN/GPR137B/WDR11/KIAA1324/SIDT2/GNB4/HLA-DMB/SLC29A3/EEF1A2/ABCA5/HLA-DQA2/CKAP4/TM6SF1/RDH14/SNAPIN/ATP6V1G1/NPRL3/LAMP1/RAB2A/VTI1B/SYNGR1/GLIPR1/CYBRD1/GOPC/LAMTOR4/ITM2C/LNPEP/HLA-DPB1/LAMTOR2/GNAQ/AHNAK/SPHK2/LMBRD1/NAPG/RAB37/VNN1/ATP11C/LAPTM4A/MANBA/VPS39/STOM/CLCN5/RRAGB/MFSD12/DRAM1/SLCO4C1/HLA-DRB1/SEH1L/RAB12/NPRL2	130
CC	GO:0000922	spindle pole	70/4919	164/19717	4.724e-07	2.595e-05	2.106e-05	CENPF/CKAP2L/AURKB/GPSM2/TPX2/ASPM/FAM83D/AURKA/NEDD9/WDR62/KIF20B/NEK2/CDC20/DLGAP5/TACC3/SPAG5/FAM110A/CDC6/SMC3/PLK2/ODF2/KIF11/PLK1/UXT/CKAP2/PSRC1/CCNB1/NUMA1/FAM110C/BOD1/TOPBP1/POC1A/UNC119/TUBGCP2/NUDCD2/PKP4/KLHL21/PPP2CA/CEP19/SBDS/BRCC3/EMD/WDR73/TOPORS/WDR60/RAE1/PRC1/BEX4/ALMS1/AUNIP/DDX11/KATNAL2/CDC14B/NSFL1C/TUBG1/UMOD/KATNBL1/KLHL22/SMC1A/EFHC1/AAAS/CEP44/TMEM201/TTC28/CEP89/CDC25B/TUBGCP5/NUP62/CKAP5/TUBGCP3	70
CC	GO:0005840	ribosome	103/4919	272/19717	1.414e-06	7.251e-05	5.886e-05	LARP4/RPL3/MRPL37/MRPL28/RPS8/RPL32/RPS25/RPS12/RPL10A/RPS18/RPS27/MRPL51/MRPS36/RPL35/RPL38/RPS10/RPS3A/RPLP2/RPL21/MRPL22/RPL19/RPL23A/DNAJC21/RPS5/RPL36/RPL5/RPL4/RPL30/MRPL18/RPL27A/RPL26/MRPS5/RPS23/RPS6/RPS15/MRPS18C/RPL36A/MRPS11/RPL7/RPL18A/RPS13/RPS20/RPL6/RPS3/NSUN4/RPS15A/HBA2/C12orf65/RPS27A/MRPS6/RPL23/RPS11/RPS19/UBA52/RPS16/MRPL20/RPS9/RPL14/MRPL50/RPL37A/MRPL36/MRPS2/RPL37/MRPL35/MRPL27/FMR1/MRPL15/HULC/MRPS25/RPL29/MRPL34/RPS4X/RPL12/MRPS14/MRPL13/MTG1/RPSA/EIF3H/EIF2D/PTCD3/RPS6KL1/EIF2AK3/RRBP1/RPS28/GADD45GIP1/MRPL10/RPL7A/SERP1/CANX/RPL39/MRPL54/DAP3/NUFIP2/HSPA14/MRPL2/RPL11/MRPL39/RBM3/GEMIN5/MRPL43/RPL22/MRPL48/MALSU1	103
CC	GO:0005774	vacuolar membrane	145/4919	412/19717	1.797e-06	8.197e-05	6.654e-05	MYO7A/ANPEP/ACPP/CD68/FPR1/ABCC1/SEC13/TLR8/GRN/ATP6V0D1/SURF4/CTSA/HPSE/ATP11A/TEX264/BRI3/SLC2A8/TM9SF1/NEU1/HLA-DQB2/SLC36A1/AP5S1/MAP1LC3A/ATP6V0B/CTNS/UBXN6/MTOR/ANXA2/LDLR/HLA-DMA/ABCD1/SLC12A4/TMEM150C/CCZ1/ITFG2/HLA-H/TMEM63A/DTX3L/ARRB1/ATP13A2/BLOC1S1/CD1B/BST2/VPS33B/ATP6V1E1/CD74/RAB3D/SNAP29/MAN2B1/CD1D/COL6A1/ATP6V0C/CALCOCO2/SLC39A11/M6PR/SBF2/TPCN1/HLA-DPA1/WDR24/ATRAID/PIGR/NFAM1/C12orf66/TMEM106B/ATP6V1A/UBA52/HLA-DRA/ULK1/AP3D1/FLOT1/PRCP/AP1S1/TOM1/LITAF/PI4K2A/AP2S1/IFITM3/LRP1/TRIM23/GBA/CTSD/TMEM30A/TMEM175/VASN/PLEKHM1/EEF1A1/SLC38A9/ABCC6/C3AR1/OCA2/CUBN/GPR137B/WDR11/KIAA1324/SIDT2/GNB4/HLA-DMB/SLC29A3/EEF1A2/UVRAG/ABCA5/HLA-DQA2/CKAP4/ENTPD4/TM6SF1/RDH14/SNAPIN/NAPB/ATP6V1G1/NPRL3/LAMP1/RAB2A/VTI1B/SYNGR1/GLIPR1/CYBRD1/GOPC/LAMTOR4/ITM2C/LNPEP/HLA-DPB1/LAMTOR2/GNAQ/AHNAK/SPHK2/TMEM150B/LMBRD1/NAPG/RAB37/VNN1/ATP11C/LAPTM4A/MANBA/VPS39/STOM/CLCN5/RRAGB/MFSD12/CCDC115/DRAM1/SLCO4C1/HLA-DRB1/SEH1L/RAB12/NPRL2	145
CC	GO:0015934	large ribosomal subunit	54/4919	121/19717	1.812e-06	8.197e-05	6.654e-05	RPL3/MRPL37/MRPL28/RPL32/RPL10A/MRPL51/RPL35/RPL38/RPLP2/RPL21/MRPL22/RPL19/RPL23A/RPL36/RPL5/RPL4/RPL30/MRPL18/RPL27A/RPL26/RPL36A/RPL7/RPL18A/RPL6/NSUN4/C12orf65/RPL23/UBA52/MRPL20/RPL14/MRPL50/RPL37A/MRPL36/RPL37/MRPL35/MRPL27/MRPL15/RPL29/MRPL34/RPL12/MRPL13/MRPL10/RPL7A/RPL39/MRPL54/MRPL2/RPL11/MRPL39/RBM3/GEMIN5/MRPL43/RPL22/MRPL48/MALSU1	54
CC	GO:0005766	primary lysosome	65/4919	155/19717	2.489e-06	0.0001007	8.177e-05	PLAC8/ACPP/CD68/FPR1/GRN/CPPED1/SURF4/CTSA/GLB1/BRI3/GM2A/ANXA2/TUBB/HLA-H/GGH/FABP5/VCP/TXNDC5/SDCBP/BST2/LYZ/PSMD1/TUBB4B/RAB3D/SNAP29/MAN2B1/ATP6V0C/TOLLIP/PIGR/NFAM1/FUCA2/PA2G4/PRCP/TOM1/SNAP23/TMEM30A/ARG1/FTL/MNDA/UNC13D/C3AR1/C6orf120/PTGES2/MPO/IST1/IMPDH1/CKAP4/PADI2/PRDX6/LAMP1/SYNGR1/GLIPR1/DEFA1B/AGA/HEXB/GUSB/DEFA4/RAB37/VNN1/MANBA/STOM/FUCA1/MAPK1/SLCO4C1/NHLRC3	65
CC	GO:0042582	azurophil granule	65/4919	155/19717	2.489e-06	0.0001007	8.177e-05	PLAC8/ACPP/CD68/FPR1/GRN/CPPED1/SURF4/CTSA/GLB1/BRI3/GM2A/ANXA2/TUBB/HLA-H/GGH/FABP5/VCP/TXNDC5/SDCBP/BST2/LYZ/PSMD1/TUBB4B/RAB3D/SNAP29/MAN2B1/ATP6V0C/TOLLIP/PIGR/NFAM1/FUCA2/PA2G4/PRCP/TOM1/SNAP23/TMEM30A/ARG1/FTL/MNDA/UNC13D/C3AR1/C6orf120/PTGES2/MPO/IST1/IMPDH1/CKAP4/PADI2/PRDX6/LAMP1/SYNGR1/GLIPR1/DEFA1B/AGA/HEXB/GUSB/DEFA4/RAB37/VNN1/MANBA/STOM/FUCA1/MAPK1/SLCO4C1/NHLRC3	65
CC	GO:0000775	chromosome, centromeric region	77/4919	193/19717	3.13e-06	0.0001203	9.769e-05	CENPF/AURKB/KIF2C/CDCA8/CENPA/SKA1/HJURP/CDCA5/BUB1B/NCAPG/TTK/PMF1/CDT1/BIRC5/ZWINT/AURKA/CENPM/RASSF2/NEK2/SEC13/ESCO2/SKA3/SPC25/ERCC6L/BUB1/SPC24/SPAG5/NCAPD2/KIF18A/PPP2R1A/SMC3/CENPW/NUF2/INCENP/NUP98/PLK1/ZNF276/CCNB1/CBX5/SNAI1/CENPE/NDC80/TP53BP1/CENPT/ZNFX1/SUMO3/CENPO/BOD1/DCTN5/CLASP2/DSCC1/NUDCD2/CENPI/PPP2CA/CENPP/CENPN/FMR1/REC8/CEBPB/HELLS/UVRAG/OIP5/STAG3/FBXO28/CENPV/APC/SMC1A/CHAMP1/KDM4C/ORC2/PPP1R12A/TRAPPC12/LRWD1/SEH1L/CKAP5/NGDN/CENPK	77
CC	GO:0015935	small ribosomal subunit	35/4919	72/19717	1.196e-05	0.000438	0.0003555	LARP4/RPS8/RPS25/RPS12/RPS18/RPS27/MRPS36/RPS10/RPS3A/RPS5/MRPS5/RPS23/RPS6/RPS15/MRPS18C/MRPS11/RPS13/RPS20/RPS3/RPS15A/HBA2/RPS27A/MRPS6/RPS11/RPS19/UBA52/RPS16/RPS9/MRPS2/RPS4X/MRPS14/RPSA/EIF2D/RPS28/DAP3	35
CC	GO:0034774	secretory granule lumen	114/4919	321/19717	1.378e-05	0.0004816	0.0003909	QPCT/VEGFA/PLAC8/MVP/PDGFA/PTPN6/LRG1/CTSH/GRN/CPPED1/CYFIP1/CTSA/GLB1/CANT1/HPSE/TIMP2/PGAM1/TEX264/GPI/HMGB1/GSN/PROS1/GM2A/NEU1/SERPINE1/ANXA2/F5/ARHGAP9/TUBB/FCN1/PKM/GGH/FABP5/ALDOC/VCP/TXNDC5/SDCBP/CLU/LYZ/PSMD1/TUBB4B/TGFB3/PSMD2/CFD/TCN1/MAN2B1/XRCC6/CTSW/ITIH3/PNP/TOLLIP/QSOX1/FUCA2/PA2G4/ACTN4/A2M/COTL1/SPTAN1/ARPC5/FERMT3/ALOX5/CTSD/PSMA5/ARG1/FTL/RAB27A/EEF1A1/MNDA/UNC13D/PSMB7/S100A11/TIMP1/C6orf120/PTGES2/CTSZ/MPO/IST1/SRGN/APRT/IMPDH1/HSPA6/SERPING1/PADI2/RARRES2/PRDX6/ALDOA/GHRL/S100A8/VTI1B/AMPD3/CNN2/DEFA1B/TIMP3/AGA/HEXB/ISLR/GUSB/DEFA4/SERPINA4/PFKL/PPBP/FUCA1/OLA1/ATG7/TGFB1/PSMB1/PSMD7/NIT2/MAPK1/PDGFB/VEGFC/NME2/NHLRC3/PSMD11	114
CC	GO:0000776	kinetochore	56/4919	135/19717	1.755e-05	0.0005867	0.0004762	CENPF/AURKB/KIF2C/CENPA/SKA1/HJURP/BUB1B/TTK/PMF1/CDT1/BIRC5/ZWINT/CENPM/RASSF2/NEK2/SEC13/SKA3/SPC25/ERCC6L/BUB1/SPC24/SPAG5/KIF18A/CENPW/NUF2/INCENP/NUP98/PLK1/ZNF276/CCNB1/CBX5/CENPE/NDC80/TP53BP1/CENPT/SUMO3/CENPO/BOD1/DCTN5/CLASP2/NUDCD2/CENPI/CENPN/REC8/FBXO28/CENPV/APC/SMC1A/CHAMP1/ORC2/PPP1R12A/TRAPPC12/LRWD1/SEH1L/CKAP5/CENPK	56
CC	GO:0000779	condensed chromosome, centromeric region	50/4919	118/19717	2.458e-05	0.0007067	0.0005737	CENPF/AURKB/KIF2C/CENPA/SKA1/HJURP/BUB1B/NCAPG/PMF1/CDT1/BIRC5/ZWINT/AURKA/CENPM/RASSF2/NEK2/SKA3/SPC25/ERCC6L/BUB1/SPC24/SPAG5/NCAPD2/CENPW/NUF2/INCENP/PLK1/ZNF276/CCNB1/CENPE/NDC80/TP53BP1/CENPT/CENPO/BOD1/DCTN5/CLASP2/NUDCD2/CENPN/REC8/CEBPB/FBXO28/CENPV/SMC1A/CHAMP1/ORC2/LRWD1/SEH1L/CKAP5/CENPK	50
CC	GO:0042470	melanosome	46/4919	106/19717	2.474e-05	0.0007067	0.0005737	MYO7A/SLC1A5/RAC1/TFRC/ANXA2P2/GPNMB/YWHAE/YWHAZ/HSPA5/CALU/TPP1/CTNS/ANXA2/CNP/MYO5A/CAPG/SLC1A4/GGH/RAB32/SDCBP/SLC3A2/PDIA4/CTSB/HPS4/FLOT1/GCHFR/CTSD/DTNBP1/SYTL1/RAB27A/ATP1B3/OCA2/TMED10/RAB38/BSG/LAMP1/RAB2A/SYNGR1/CANX/GANAB/FASN/RAB1A/STOM/TMEM33/TYRP1/PRDX1	46
CC	GO:0048770	pigment granule	46/4919	106/19717	2.474e-05	0.0007067	0.0005737	MYO7A/SLC1A5/RAC1/TFRC/ANXA2P2/GPNMB/YWHAE/YWHAZ/HSPA5/CALU/TPP1/CTNS/ANXA2/CNP/MYO5A/CAPG/SLC1A4/GGH/RAB32/SDCBP/SLC3A2/PDIA4/CTSB/HPS4/FLOT1/GCHFR/CTSD/DTNBP1/SYTL1/RAB27A/ATP1B3/OCA2/TMED10/RAB38/BSG/LAMP1/RAB2A/SYNGR1/CANX/GANAB/FASN/RAB1A/STOM/TMEM33/TYRP1/PRDX1	46
CC	GO:0072686	mitotic spindle	47/4919	109/19717	2.481e-05	0.0007067	0.0005737	ESPL1/CKAP2L/AURKB/GPSM2/TPX2/SKA1/KIFC1/ASPM/FAM83D/GEM/CDK1/AURKA/KIF23/KIF20B/NUSAP1/EML4/TACC3/SPAG5/RACGAP1/KIF18A/SMC3/CTTN/KIF11/CENPE/NUMA1/CAPG/KAT2A/PKD2/RPS3/CLASP2/PKP4/RAE1/ECT2/SIRT2/CDC14B/KATNBL1/KLHL22/TBCK/SMC1A/MAP9/EFHC1/AAAS/CDC42/TTC28/MAPK1/NUP62/NCOR1	47
CC	GO:0051233	spindle midzone	20/4919	34/19717	2.736e-05	0.0007165	0.0005816	AURKB/CDCA8/KIF14/GEM/AURKA/KIF20B/RACGAP1/KIF18A/CDC6/CTTN/PLK1/MAPRE2/CENPE/NUMA1/UNC119/PKP4/CCDC69/CENPV/MAP9/CDC42	20
CC	GO:0022625	cytosolic large ribosomal subunit	31/4919	63/19717	2.741e-05	0.0007165	0.0005816	RPL3/RPL32/RPL10A/RPL35/RPL38/RPLP2/RPL21/RPL19/RPL23A/RPL36/RPL5/RPL4/RPL30/RPL27A/RPL26/RPL36A/RPL7/RPL18A/RPL6/RPL23/UBA52/RPL14/RPL37A/RPL37/RPL29/RPL12/RPL7A/RPL39/RPL11/GEMIN5/RPL22	31
CC	GO:0000151	ubiquitin ligase complex	101/4919	282/19717	2.804e-05	0.0007165	0.0005816	CCNF/RNF144A/UBE2C/BUB1B/DTL/CDC20/UBE2A/DCAF12/KCTD17/UBE2S/FBXL19/DDB2/ZSWIM5/DERL1/SPSB1/UBE2B/DET1/MED20/ASB2/KLHL25/TRAF7/SYVN1/AMN1/GID8/CKS2/TSPAN17/KCTD5/UBE3D/TNFAIP1/FBXL18/CKS1B/KLHL3/UBE2N/FBXL14/BCOR/KLHL9/FBXO48/RNF40/FBXO27/FBXO31/UBE4A/CBX8/PHC3/ERCC8/CBX2/PHC2/KLHL21/FBXL8/RNF8/ZSWIM6/MAEA/DCAF10/ANAPC11/RNF19B/BRCC3/PCGF6/FBXW11/PCGF1/TOPORS/CBX7/CUL5/DCAF5/SPSB2/DCAF4/DCAF15/DCUN1D4/ANAPC1/RNF7/DCAF17/BTRC/PCGF5/GAN/TRAF2/FBXL4/FBXO11/KCTD13/ZYG11B/LZTR1/FBXO9/UBR2/RANBP10/MAD2L2/KLHL22/FBXL15/FBXL20/MED12/FBXO44/KLHL7/ANAPC13/ASB1/CUL4A/GLMN/FBXO10/BMI1/PEF1/CDC16/CRBN/FBXO4/KLHL13/BARD1/RNF168	101
CC	GO:0070938	contractile ring	9/4919	10/19717	2.889e-05	0.0007165	0.0005816	ANLN/KIF20B/RTKN/PDXP/MAEA/PRC1/MYH9/UTRN/ALKBH4	9
CC	GO:0001726	ruffle	67/4919	172/19717	3.278e-05	0.0007878	0.0006395	RASGRP2/LAYN/FSCN1/RINL/SH2B2/RAC1/FRMD4B/CYFIP1/TIRAP/CORO1C/KSR1/KIF18A/PDE4A/NF2/SNX9/TNFRSF12A/GSN/FGD2/CTTN/ANXA2/MYADM/IFIT5/PLEKHA1/MYO5A/SRC/PSD4/CAPG/TIAM1/ARHGEF2/SAMSN1/PDXP/PAK1/SH3YL1/AMOT/RPS3/HIP1R/PDLIM7/PTK6/EPS8L2/MTMR9/EZR/CLASP2/S100A6/AIF1/CFL1/EEF1A1/PSD3/ARAP3/EPB41L5/S100A11/MTMR14/ARF4/CD2AP/MYH9/TESC/PACSIN1/ARF6/TPM1/AIF1L/APC/PARD6A/PPP1R9B/WASF2/PIP5K1A/SPATA13/NME2/ARHGEF26	67
CC	GO:0000777	condensed chromosome kinetochore	45/4919	105/19717	4.384e-05	0.001022	0.0008293	CENPF/KIF2C/CENPA/SKA1/HJURP/BUB1B/PMF1/CDT1/BIRC5/ZWINT/CENPM/RASSF2/NEK2/SKA3/SPC25/ERCC6L/BUB1/SPC24/SPAG5/CENPW/NUF2/INCENP/PLK1/ZNF276/CCNB1/CENPE/NDC80/TP53BP1/CENPT/CENPO/BOD1/DCTN5/CLASP2/NUDCD2/CENPN/REC8/FBXO28/CENPV/SMC1A/CHAMP1/ORC2/LRWD1/SEH1L/CKAP5/CENPK	45
CC	GO:0031461	cullin-RING ubiquitin ligase complex	62/4919	158/19717	4.904e-05	0.001109	0.0009003	CCNF/UBE2C/BUB1B/DTL/CDC20/DCAF12/KCTD17/UBE2S/FBXL19/DDB2/ZSWIM5/SPSB1/DET1/KLHL25/AMN1/CKS2/KCTD5/TNFAIP1/FBXL18/CKS1B/KLHL3/FBXL14/KLHL9/FBXO48/FBXO27/FBXO31/ERCC8/KLHL21/FBXL8/ZSWIM6/DCAF10/ANAPC11/FBXW11/CUL5/DCAF5/SPSB2/DCAF4/DCAF15/ANAPC1/RNF7/DCAF17/BTRC/GAN/FBXL4/KCTD13/ZYG11B/LZTR1/FBXO9/MAD2L2/KLHL22/FBXL15/FBXL20/FBXO44/KLHL7/ANAPC13/CUL4A/GLMN/PEF1/CDC16/CRBN/FBXO4/KLHL13	62
CC	GO:0045171	intercellular bridge	29/4919	59/19717	5.061e-05	0.001112	0.0009027	KIF20A/CDCA8/TPX2/KIF4A/KIF23/CEP55/MICAL1/TRIM45/ESRRA/USB1/RFXANK/KIF4B/UNC119/QSOX1/FASTKD2/PRKCI/RAB11FIP3/THAP11/GSTM1/SNRNP25/EAF1/CD34/NCAPH2/PRKACB/XPA/FAN1/SRA1/NINL/KLHDC8B	29
CC	GO:0000793	condensed chromosome	82/4919	223/19717	5.401e-05	0.001154	0.0009365	CENPF/AURKB/KIF2C/CENPA/SKA1/HJURP/CDCA5/BUB1B/NCAPG/PMF1/MKI67/CDT1/TOP2A/BIRC5/ZWINT/AURKA/CENPM/HSPA2/RASSF2/NEK2/SKA3/SPC25/ERCC6L/BUB1/SPC24/SPAG5/NCAPD2/SMC3/CENPW/SYN1/SYCE3/HMGB1/NUF2/INCENP/BRCA2/PLK1/RAD51/ZNF276/CCNB1/CENPE/NDC80/TP53BP1/UBE2I/CDK2/CENPT/DMC1/ADD3/CENPO/BOD1/TOPBP1/SUN2/DCTN5/CLASP2/EID3/BRD4/NUDCD2/BANF1/NCAPH/CENPN/REC8/CHEK1/CEBPB/STAG3/RCC1/FBXO28/SYCE2/CHMP1A/LRPPRC/NCAPH2/TUBG1/CENPV/SMC1A/CHAMP1/MLH3/SMC5/RNF212/ORC2/LRWD1/SEH1L/CKAP5/CENPK/RAD9A	82
CC	GO:0005874	microtubule	139/4919	416/19717	5.645e-05	0.001173	0.0009524	TUBB6/KIF20A/AURKB/KIF2C/TPX2/KIF14/SKA1/KIFC1/GTSE1/ASPM/KIF4A/KIF15/CDK1/BIRC5/MAP6/AURKA/KIF23/KIF24/KIF20B/NEK2/SKA3/NUSAP1/EML4/GAS2L3/KIF1C/SPAG5/RACGAP1/TUBA1B/CDK5/REEP2/KIF18A/TUBA1C/REEP3/TTC30A/INCENP/ODF2/KIF11/SVIL/MAP1LC3A/PLK1/CCDC66/CENPJ/CKAP2/KLC1/FSD1/TUBB/PSRC1/MYO5A/TPPP3/TPPP/MAPRE2/CENPE/NUMA1/TIAM1/ARHGEF2/DYNLRB1/REEP4/KIF4B/TUBB4B/RAB3D/PBXIP1/CDK2AP2/JAKMIP1/FAM110C/BOD1/KLC3/ENKD1/CCT5/MDM1/TUBGCP2/FGF13/CYLD/NDRG1/EML5/STMN1/CLASP2/ARHGAP4/TUBE1/TUBB3/DVL1/KLHL21/EFHC2/TUBG2/SS18/MAP3K11/RASSF3/MID1/TTLL1/KIF3C/NICN1/MID2/SPAG6/TUBB2A/HOOK2/EMD/INVS/TUBB4A/MAP1S/SHROOM1/PRC1/TRIM54/BEX4/KLC4/HAUS5/SHROOM3/BAG2/DNAI2/SIRT2/KATNAL2/DNM1/LRPPRC/TUBG1/SERP1/FAM161B/MAP1A/KLHL22/TEKT2/MTA1/APC/ODF3L2/MAP9/TCP11L1/ARL3/WHAMM/SLAIN2/BCAS3/KIF26B/TCTE3/TUBGCP5/NCKAP5/KIF19/CDC16/SYBU/CKAP5/NINL/KIFC2/DNAH6/CCT3/TUBGCP3	139
CC	GO:0005775	vacuolar lumen	66/4919	172/19717	6.425e-05	0.001271	0.001032	PLAC8/SDC4/CD1E/GRN/CPPED1/CTSA/NEU4/GLB1/DAPK2/HPSE/GPC1/IFI30/GM2A/NEU1/TPP1/ANXA2/TUBB/IDS/OGN/GGH/IDUA/FABP5/VCP/TXNDC5/SDCBP/ATP13A2/LYZ/SDC2/PSMD1/TUBB4B/CD74/PPT1/MAN2B1/CTSF/CTSB/TCN2/TOLLIP/SDC1/FUCA2/PA2G4/GBA/CTSD/ARG1/FTL/GPC2/MNDA/UNC13D/CUBN/C6orf120/PTGES2/MPO/IST1/IMPDH1/PADI2/PRDX6/CHID1/DEFA1B/GALC/AGA/HEXB/GUSB/LIPA/MANBA/FUCA1/MAPK1/NHLRC3	66
CC	GO:0060205	cytoplasmic vesicle lumen	116/4919	338/19717	6.447e-05	0.001271	0.001032	QPCT/VEGFA/PLAC8/MVP/PDGFA/PTPN6/LRG1/CTSH/GRN/CPPED1/CYFIP1/CTSA/GLB1/CANT1/HPSE/TIMP2/PGAM1/TEX264/GPI/HMGB1/GSN/PROS1/GM2A/NEU1/SERPINE1/ANXA2/F5/ARHGAP9/TUBB/FCN1/PKM/GGH/FABP5/ALDOC/VCP/TXNDC5/SDCBP/CLU/LYZ/PSMD1/TUBB4B/TGFB3/PSMD2/CFD/TCN1/MAN2B1/XRCC6/CTSW/HBA2/ITIH3/PNP/TOLLIP/QSOX1/FUCA2/PA2G4/ACTN4/A2M/COTL1/SPTAN1/ARPC5/FERMT3/ALOX5/CTSD/PSMA5/ARG1/FTL/RAB27A/EEF1A1/MNDA/UNC13D/PSMB7/S100A11/TIMP1/C6orf120/PTGES2/CTSZ/MPO/IST1/SRGN/APRT/IMPDH1/HSPA6/SERPING1/PADI2/RARRES2/PRDX6/ALDOA/GHRL/S100A8/VTI1B/AMPD3/HBB/CNN2/DEFA1B/TIMP3/AGA/HEXB/ISLR/GUSB/DEFA4/SERPINA4/PFKL/PPBP/FUCA1/OLA1/ATG7/TGFB1/PSMB1/PSMD7/NIT2/MAPK1/PDGFB/VEGFC/NME2/NHLRC3/PSMD11	116
CC	GO:0031983	vesicle lumen	116/4919	339/19717	7.424e-05	0.001427	0.001158	QPCT/VEGFA/PLAC8/MVP/PDGFA/PTPN6/LRG1/CTSH/GRN/CPPED1/CYFIP1/CTSA/GLB1/CANT1/HPSE/TIMP2/PGAM1/TEX264/GPI/HMGB1/GSN/PROS1/GM2A/NEU1/SERPINE1/ANXA2/F5/ARHGAP9/TUBB/FCN1/PKM/GGH/FABP5/ALDOC/VCP/TXNDC5/SDCBP/CLU/LYZ/PSMD1/TUBB4B/TGFB3/PSMD2/CFD/TCN1/MAN2B1/XRCC6/CTSW/HBA2/ITIH3/PNP/TOLLIP/QSOX1/FUCA2/PA2G4/ACTN4/A2M/COTL1/SPTAN1/ARPC5/FERMT3/ALOX5/CTSD/PSMA5/ARG1/FTL/RAB27A/EEF1A1/MNDA/UNC13D/PSMB7/S100A11/TIMP1/C6orf120/PTGES2/CTSZ/MPO/IST1/SRGN/APRT/IMPDH1/HSPA6/SERPING1/PADI2/RARRES2/PRDX6/ALDOA/GHRL/S100A8/VTI1B/AMPD3/HBB/CNN2/DEFA1B/TIMP3/AGA/HEXB/ISLR/GUSB/DEFA4/SERPINA4/PFKL/PPBP/FUCA1/OLA1/ATG7/TGFB1/PSMB1/PSMD7/NIT2/MAPK1/PDGFB/VEGFC/NME2/NHLRC3/PSMD11	116
CC	GO:0031252	cell leading edge	134/4919	403/19717	9.749e-05	0.001829	0.001484	RASGRP2/TIAM2/LAYN/FSCN1/ABLIM1/PTPN13/RINL/ADORA2A/SH2B2/NEDD9/RAC1/FRMD4B/CYFIP1/TIRAP/CDK5/CDC42BPG/CORO1C/KSR1/KIF18A/PDE4A/NF2/SNX9/TNFRSF12A/MYH10/AKAP5/SRGAP2/GSN/FGD2/ANK1/CTTN/NHS/ANXA2/MYADM/IFIT5/PLEKHA1/DOCK8/SWAP70/MYO5A/SRC/PSD4/PDLIM4/ACTG2/DGKZ/CAPG/TIAM1/ARHGEF2/SCIMP/CORO1B/SAMSN1/PDXP/RAB13/ARHGAP31/PAK1/APBB1IP/CD177/SH3YL1/PKD2/ATF4/AMOT/RPS3/HIP1R/LMO4/PDLIM7/PTK6/EPS8L2/FAM89B/SPTBN1/MTMR9/EZR/CORO1A/CLASP2/VASP/S100A6/AIF1/PRKCI/TWF2/CFL1/PLXND1/PARVB/TUBB3/DUSP22/FLOT1/SCRIB/ARPC5/AAK1/LIMK1/THY1/NRBP1/SCYL3/EEF1A1/PSD3/ARAP3/GBF1/EPB41L5/S100A11/CD44/PIEZO1/RAC2/PTPRM/VIM/MTMR14/GABRG2/CTNNA1/ARF4/CD2AP/MYH9/KCNC4/FER/STX2/TUBG1/TESC/PACSIN1/INSR/ARF6/TPM1/AIF1L/APC/PARD6A/ACTA2/PPP1R9B/WASF2/RAPH1/PIP5K1A/RUFY3/BCAS3/SYNE2/SRA1/LDB1/SPATA13/NME2/ARHGEF26/ILK/RAC3/SHISA7	134
CC	GO:0000778	condensed nuclear chromosome kinetochore	11/4919	15/19717	0.0001123	0.002056	0.001669	CENPA/BUB1B/PMF1/BUB1/NUF2/PLK1/CCNB1/NDC80/CENPO/REC8/CENPK	11
CC	GO:0000152	nuclear ubiquitin ligase complex	22/4919	43/19717	0.0001918	0.003431	0.002785	UBE2C/BUB1B/CDC20/UBE2S/BCOR/CBX8/PHC3/CBX2/PHC2/ANAPC11/BRCC3/PCGF6/PCGF1/CBX7/ANAPC1/RNF7/PCGF5/MAD2L2/ANAPC13/BMI1/CDC16/BARD1	22
CC	GO:0044450	microtubule organizing center part	68/4919	185/19717	0.0002265	0.00387	0.003141	CCNF/STIL/TOP2A/AURKA/CEP55/WDR62/KIF24/DYRK3/SPAG5/PLK4/HSPA1A/PLK2/ODF2/PLK1/CCDC66/CENPJ/UXT/WDR34/FGFR1OP/MZT2A/CAPG/CCDC146/PDE4B/NEURL4/POC1A/HTT/NUBP1/MDM1/TUBGCP2/CEP152/TUBE1/SFI1/FLOT1/TNKS2/CEP19/TUBG2/ZMYND10/BBS9/MZT2B/TOPORS/WDR60/MARK4/PIBF1/CEP192/TSGA10/C10orf90/NEK1/ALMS1/HSPA6/WRAP73/SIRT2/TSKS/ACTR1A/TUBG1/CETN2/CEP72/PARD6A/CETN3/ALDOB/AGBL2/HERC2/STARD9/CEP89/TUBGCP5/CCHCR1/MPHOSPH9/CKAP5/TUBGCP3	68
CC	GO:0101002	ficolin-1-rich granule	68/4919	185/19717	0.0002265	0.00387	0.003141	QPCT/MVP/FPR1/RAC1/LRG1/SERPINB6/CTSH/SIRPA/GLB1/CANT1/TIMP2/LGALS3/PGAM1/MMP9/GPI/HMGB1/GSN/HSPA1A/CAPN1/SLC2A3/ITGAX/FCN1/PKM/ALDOC/PLEKHO2/VCP/CST3/PSMD2/CFD/XRCC6/CTSB/ATP6V0C/TBC1D10C/PNP/PRG2/COTL1/PRCP/ARPC5/ALOX5/CD58/LILRB2/CTSD/PSMA5/EEF1A1/MNDA/FPR2/ENPP4/CLEC4D/PSMB7/CTSZ/FTH1/FCAR/IMPDH1/HSPA6/LAMP1/ALDOA/AMPD3/HBB/GUSB/PFKL/ATG7/PSMB1/PSMD7/MAPK1/DSC1/NME2/CD93/PSMD11	68
CC	GO:1904813	ficolin-1-rich granule lumen	49/4919	124/19717	0.0002368	0.003959	0.003213	QPCT/MVP/LRG1/CTSH/GLB1/CANT1/TIMP2/PGAM1/MMP9/GPI/HMGB1/GSN/HSPA1A/CAPN1/FCN1/PKM/ALDOC/PLEKHO2/VCP/CST3/PSMD2/CFD/XRCC6/CTSB/PNP/PRG2/COTL1/ARPC5/ALOX5/CTSD/PSMA5/EEF1A1/MNDA/PSMB7/CTSZ/FTH1/IMPDH1/HSPA6/ALDOA/AMPD3/HBB/GUSB/PFKL/ATG7/PSMB1/PSMD7/MAPK1/NME2/PSMD11	49
CC	GO:0035578	azurophil granule lumen	38/4919	91/19717	0.0003157	0.005166	0.004193	PLAC8/GRN/CPPED1/CTSA/GLB1/GM2A/ANXA2/TUBB/GGH/FABP5/VCP/TXNDC5/SDCBP/LYZ/PSMD1/TUBB4B/MAN2B1/TOLLIP/FUCA2/PA2G4/ARG1/FTL/MNDA/UNC13D/C6orf120/PTGES2/MPO/IST1/IMPDH1/PADI2/PRDX6/DEFA1B/AGA/HEXB/GUSB/FUCA1/MAPK1/NHLRC3	38
CC	GO:0010369	chromocenter	10/4919	14/19717	0.0003339	0.00535	0.004342	AURKB/CDCA8/ESCO2/INCENP/CBX5/MBD6/MBD5/FMR1/OIP5/TINF2	10
CC	GO:0000930	gamma-tubulin complex	13/4919	21/19717	0.0003608	0.005662	0.004596	CENPJ/UXT/MZT2A/PDE4B/TUBGCP2/TUBG2/MZT2B/TOPORS/MARK4/TUBG1/TUBGCP5/CKAP5/TUBGCP3	13
CC	GO:0030176	integral component of endoplasmic reticulum membrane	56/4919	150/19717	0.0004966	0.007564	0.006139	SGMS1/DOLPP1/SGMS2/HSPA5/DERL1/HLA-DQB2/SPPL3/TECR/ZFYVE27/SYVN1/SLC35B1/FITM2/HLA-H/SCD/HLA-G/EMC9/SLC27A2/PIGK/DNAJB12/FITM1/CD74/PKD2/DPM2/HLA-DPA1/BCAP31/HLA-E/SLC35B2/HLA-DRA/EXT1/INSIG1/RCE1/RTN1/TAP1/ELOVL7/FKBP8/ELOVL1/FICD/HLA-DQA2/EMC10/EIF2AK3/RRBP1/BSCL2/ERN1/DGAT2/CANX/XXYLT1/SLC37A3/HLA-DPB1/SLC35B4/PORCN/DOLK/TMEM33/HLA-DRB1/SREBF2/PIGG/PIGT	56
CC	GO:0000794	condensed nuclear chromosome	40/4919	99/19717	0.0005016	0.007564	0.006139	AURKB/CENPA/BUB1B/PMF1/AURKA/HSPA2/NEK2/BUB1/NCAPD2/SMC3/SYN1/SYCE3/NUF2/INCENP/BRCA2/PLK1/RAD51/CCNB1/NDC80/UBE2I/DMC1/ADD3/CENPO/TOPBP1/SUN2/BRD4/NCAPH/REC8/CHEK1/STAG3/RCC1/SYCE2/CHMP1A/LRPPRC/TUBG1/SMC1A/MLH3/RNF212/CENPK/RAD9A	40
CC	GO:0032155	cell division site part	28/4919	63/19717	0.0005719	0.008243	0.006691	KIF20A/ANLN/CIT/CEP55/RACGAP1/PLCD3/PLK4/RTKN/NF2/STAMBP/MYH10/SVIL/FSD1/PDXP/PITPNM1/TUBGCP2/RALA/MAEA/RAB11FIP3/ICAM2/WDR73/ECT2/MYH9/RAB11FIP4/ARF6/TUBGCP5/KLHDC8B/TUBGCP3	28
CC	GO:0000792	heterochromatin	33/4919	78/19717	0.0005762	0.008243	0.006691	CENPA/ESCO2/UBE2A/UHRF1/PML/INCENP/SIRT6/UBE2B/CBX5/SNAI1/MBD2/MORC2/SATB1/RNF40/CBX8/SALL4/EED/CBX2/PHC2/CDKN2A/SUMO1/WDR76/HELLS/EME1/SIRT2/BAZ2A/RRP8/UHRF2/SIRT7/KDM4C/ORC2/LRWD1/SIRT1	33
CC	GO:0042788	polysomal ribosome	17/4919	32/19717	0.0005788	0.008243	0.006691	RPL32/RPL10A/RPL38/RPL19/RPL36/RPL30/RPS23/RPL36A/RPL18A/RPL6/FMR1/EIF3H/RPS28/RPL7A/RPL39/NUFIP2/RPL11	17
CC	GO:0010008	endosome membrane	151/4919	479/19717	0.0005986	0.008369	0.006793	NDFIP2/RNF144A/FURIN/SNX8/IRF7/RAB31/NTRK2/CD68/SLC1A1/NTRK1/FCGR1B/RAC1/TLR8/EPHB1/PMEPA1/MRC1/ATP6V0D1/RFFL/TFRC/NCF4/SNX25/PARM1/GPNMB/CORO1C/PML/CHMP2B/CD1A/FGD2/TLR4/HLA-DQB2/AP5S1/ATP6V0B/PLEKHM2/UBXN6/ANXA2/LDLR/ZFYVE27/HLA-DMA/CD1C/STEAP3/PLIN3/SNF8/FCGR1A/SORL1/HLA-H/PDLIM4/GRIPAP1/DTX3L/CD207/ATG9A/HLA-G/CLIP3/ATP13A2/CD1B/RAB13/STAM/VPS33B/UBB/GGA2/ZFYVE9/CD1D/SUN2/ATP6V0C/SH3GL1/PIKFYVE/RPS27A/MICALL1/SBF2/TPCN1/HLA-DPA1/NDRG1/SLC9A7/TMEM106B/HLA-E/UBA52/HLA-DRA/AP3D1/ANTXR2/LITAF/AP2S1/IFITM3/IRAK1/CTSD/SLA2/DTNBP1/HGS/TMEM175/STX12/RAB27A/PLEKHM1/LDLRAD4/ACAP1/SLC38A9/RAB11FIP3/OCA2/CUBN/SNX19/ERBB2/TAB1/YIPF2/VAMP3/PRAF2/VPS52/KIAA1324/HLA-DMB/SLC29A3/RABGEF1/ABCA5/HLA-DQA2/RHOV/PLEKHB2/ITM2B/RAB23/LAMP1/VTI1B/CHMP1A/EEA1/RAB11FIP5/RAB11FIP4/LZTR1/CLVS1/LAMTOR4/LRP6/SORCS2/HLA-DPB1/CHMP2A/LAMTOR2/INSR/RAB15/TRAF6/ARF6/ZDHHC2/TMEM150B/LAPTM4A/FZD5/VPS39/CLCN5/SLC9B2/ARHGAP1/MITD1/EHD3/ARHGAP32/TYRP1/TOM1L1/HLA-DRB1/CHMP3/EHD4/OSBPL9/GPR135/RAB12/SLC9A6	151
CC	GO:0031227	intrinsic component of endoplasmic reticulum membrane	58/4919	158/19717	0.0006517	0.008949	0.007264	SGMS1/DOLPP1/SGMS2/HSPA5/DERL1/HLA-DQB2/SPPL3/TECR/ZFYVE27/SYVN1/SLC35B1/FITM2/HLA-H/SCD/HLA-G/EMC9/SLC27A2/PIGK/DNAJB12/FITM1/CD74/PKD2/DPM2/HLA-DPA1/BCAP31/HLA-E/SLC35B2/HLA-DRA/EXT1/INSIG1/RCE1/RTN1/TAP1/ELOVL7/FKBP8/ELOVL1/FICD/HLA-DQA2/EMC10/EIF2AK3/RRBP1/BSCL2/ERN1/DGAT2/CANX/XXYLT1/SLC37A3/HLA-DPB1/SLC35B4/GRAMD1A/PORCN/DOLK/TMEM33/DNAJB2/HLA-DRB1/SREBF2/PIGG/PIGT	58
CC	GO:0030027	lamellipodium	68/4919	193/19717	0.0008775	0.01184	0.009609	TIAM2/FSCN1/ABLIM1/PTPN13/NEDD9/RAC1/CYFIP1/CDK5/CORO1C/NF2/MYH10/SRGAP2/GSN/FGD2/CTTN/NHS/DOCK8/SWAP70/PDLIM4/ACTG2/DGKZ/CAPG/CORO1B/PDXP/RAB13/ARHGAP31/PAK1/APBB1IP/CD177/PKD2/AMOT/FAM89B/CORO1A/VASP/AIF1/TWF2/CFL1/PLXND1/PARVB/TUBB3/DUSP22/FLOT1/SCRIB/ARPC5/LIMK1/NRBP1/SCYL3/ARAP3/CD44/PIEZO1/RAC2/PTPRM/CTNNA1/FER/STX2/TESC/APC/ACTA2/PPP1R9B/WASF2/RAPH1/PIP5K1A/RUFY3/SYNE2/SPATA13/NME2/ILK/RAC3	68
CC	GO:1905368	peptidase complex	36/4919	89/19717	0.0009116	0.01209	0.009811	PSMD8/VCP/ENY2/PSMD1/PSMD2/PSMF1/RAD23B/TAF9B/SEC11C/PSMD9/PSMA5/TAF6L/PSMB7/UBE3A/RAD23A/PSMD5/UCHL5/PSME2/F3/ZFAND2A/PSMB5/ZFAND2B/TAF6/PSMB4/PSMA3/PAAF1/SPCS3/PSMD10/PSMB1/PSMD7/PSMB3/DNAJB2/SPG7/PSMC5/TADA1/PSMD11	36
CC	GO:0031301	integral component of organelle membrane	74/4919	214/19717	0.0009819	0.0127	0.01031	FURIN/SLC35A2/SGMS1/SFXN1/SCO2/GALNT2/SGMS2/TMEM43/TIMM17A/VOPP1/ABCD1/GDAP1/SLC35B1/P2RX1/SYT4/FAR2/CSGALNACT1/SLC27A2/ATP13A2/MICU1/P2RX6/SUN2/TMEM11/FKTN/COX18/SYNJ2BP/BID/PINK1/QSOX1/TBC1D20/SLC35B2/LEMD3/COA3/BAK1/CHCHD6/STX12/CNR1/SLC38A9/PEX2/SYT11/VAMP3/SCO1/ACER2/STX16/ENTPD4/YIF1A/PEX3/ITM2B/YIF1B/LAMP1/SYNGR1/CPT1A/P2RX5/PCSK4/PTPRS/RHOT2/PPOX/PEX11A/FUNDC2/UNC50/PCSK5/SLC35B4/SLC25A4/AGK/TMEM201/PEX13/MPC1/COX11/SV2A/SPG7/P2RX7/TRABD2B/MGARP/FUNDC1	74
CC	GO:0030666	endocytic vesicle membrane	60/4919	167/19717	0.0009906	0.0127	0.01031	HBEGF/RAB31/FCGR1B/RAB11FIP1/ATP6V0D1/HIP1/PTCH1/CD9/GPR161/CYBB/HLA-DQB2/ATP6V0B/LDLR/FCGR1A/HLA-H/CD207/HLA-G/RAB32/CAMK2A/UBB/CD74/HIP1R/ATP6V0C/RPS27A/PICK1/HLA-DPA1/CORO1A/HLA-E/CACNG3/UBA52/SCARF1/TLR2/HLA-DRA/HVCN1/AP2S1/LRP1/SNAP23/TAP1/WNT7A/TLR6/RAPGEF1/CAMK2G/RAC2/VAMP3/RAB38/CYBA/HLA-DQA2/RAB23/LAMP1/PIK3C3/CAMK2D/COLEC12/HLA-DPB1/PIK3R4/RAB34/FZD5/KIAA1107/TYRP1/HLA-DRB1/DLG4	60
CC	GO:0032153	cell division site	29/4919	68/19717	0.001039	0.01277	0.01037	KIF20A/ANLN/CIT/CEP55/RACGAP1/PLCD3/PLK4/RTKN/NF2/STAMBP/MYH10/SVIL/FSD1/PDXP/PITPNM1/TUBGCP2/RALA/MAEA/RAB11FIP3/ICAM2/WDR73/ECT2/RHOF/MYH9/RAB11FIP4/ARF6/TUBGCP5/KLHDC8B/TUBGCP3	29
CC	GO:0016605	PML body	39/4919	99/19717	0.001046	0.01277	0.01037	SQSTM1/TOP3A/TP53INP2/SP140/PML/SKI/MTOR/RAD51/CBX5/UBE2I/SUMO3/RFWD3/TOPBP1/N4BP1/SATB1/ISG20/LRCH4/TCF7L2/PIAS1/TP53INP1/SUMO1/CASP8AP2/UBN1/PARK7/TOPORS/PIAS2/ARNTL/PIAS4/ATR/CHEK2/MAX/EIF3E/SMC5/ZNF451/NR2C1/TRIM16/KAT6A/MAGEA2B/SIRT1	39
CC	GO:0070820	tertiary granule	59/4919	164/19717	0.001046	0.01277	0.01037	QPCT/FPR1/RAC1/PTPN6/LRG1/SERPINB6/CTSH/CYSTM1/CYFIP1/OLR1/LAIR1/SIRPA/CANT1/TIMP2/LGALS3/CEACAM1/ATP11A/MMP9/ATP8B4/CYBB/PLAU/SLC2A3/ITGAX/TMEM63A/GGH/ALDOC/CST3/LYZ/CD33/TCN1/CD177/ATP6V0C/TBC1D10C/QSOX1/CD47/SPTAN1/PRCP/CD58/LILRB2/SNAP23/CTSD/FPR2/ENPP4/CLEC4D/FTH1/FCAR/CYBA/LAMP1/ALDOA/HBB/CLEC5A/CNN2/LAMTOR2/PPBP/STOM/NIT2/PTAFR/DSC1/CD93	59
CC	GO:0005635	nuclear envelope	145/4919	464/19717	0.001129	0.01356	0.01101	NR4A1/CENPF/SLC16A3/SLC29A2/TYRO3/DTL/MVP/LMNB1/BNIP3L/SEC13/SMOX/GAPDH/TREX1/ALOX5AP/TFPT/SP140/MX1/TOR3A/AGPAT3/NUP98/CYBB/RGPD2/BAX/HTATIP2/TNRC18/LMNB2/TMEM43/CLIC1/LMNA/TUBB/CSE1L/SORL1/NUDT1/CBX5/P2RX1/TMC8/PDE4D/RRP12/UBE2I/RRM1/DNAJB12/SDCBP/ENY2/MYOF/LRRC59/PAK1/P2RX6/FAM169A/NUP153/SUN2/DCTN5/IL15RA/TMEM120B/CEP70/TMEM120A/TBC1D20/ATRAID/YEATS4/S100A6/ROGDI/LEMD3/TNKS2/PARP16/GCHFR/ALOX5/FAM156B/THAP7/BANF1/SPAG4/NUP88/SUMO1/GPX4/EMD/SEPHS1/KPNA3/ANXA4/TMEM170A/PARP11/POM121C/CLCA2/RAC2/NUP205/TMPO/RAE1/PHLPP1/INA/AEN/BCL2L1/IST1/NUP50/TMEM176B/RCC1/SYNE3/NUCB2/SMAD1/RAP1GAP2/LRPPRC/POM121L2/ERN1/P2RX5/PRNP/ZNF224/DHRS2/RAB40B/MGST2/POLR2M/YBX1/GRK5/ZNF383/GLE1/CETN2/SNUPN/CHMP2A/GNAQ/INSR/TXLNG/TRPC7/DTX2/MTA1/UNC50/NUP93/DDX19A/MGST3/CETN3/NUP35/SHISA5/AAAS/TMEM201/ANKRD17/PLCB1/TMEM33/SCRN1/CERS3/BNIP2/MLX/DNAJB2/RGPD1/SYNE2/NUP62/PHF8/P2RX7/SEH1L/LPIN1/SPIN1/SIRT1	145
CC	GO:0000307	cyclin-dependent protein kinase holoenzyme complex	20/4919	42/19717	0.001205	0.01425	0.01157	CCNF/CDK1/CDKN1A/CCNG2/CCNA2/CCNB2/CKS2/CCNB1/CDK2/CKS1B/CCNE2/CDK14/CDK7/CCNT2/CCNK/CCNJ/MNAT1/CCNY/CCNI/CCND1	20
CC	GO:0005844	polysome	30/4919	72/19717	0.001349	0.01572	0.01276	LARP4/MYH10/RPL32/RPL10A/RPL38/RPL19/RPL36/RPL30/RPS23/RPS6/RPL36A/MSI2/RPL18A/RPL6/RPS3/DIS3L2/EIF4H/FMR1/MCRS1/RPS4X/VIM/EIF3H/NAA38/RPS28/RPL7A/RPL39/NUFIP2/HSPA14/RPL11/UNK	30
CC	GO:0000502	proteasome complex	27/4919	63/19717	0.001397	0.01573	0.01277	PSMD8/VCP/PSMD1/PSMD2/PSMF1/RAD23B/PSMD9/PSMA5/PSMB7/UBE3A/RAD23A/PSMD5/UCHL5/PSME2/ZFAND2A/PSMB5/ZFAND2B/PSMB4/PSMA3/PAAF1/PSMD10/PSMB1/PSMD7/PSMB3/DNAJB2/PSMC5/PSMD11	27
CC	GO:0030139	endocytic vesicle	99/4919	303/19717	0.001408	0.01573	0.01277	CDC42EP4/HBEGF/RAB31/FCGR1B/ZYX/RAB11FIP1/ATP6V0D1/TIRAP/NCF4/MYO1E/HIP1/PTCH1/CD9/CLTB/UNC93B1/PLD4/GPR161/SRGAP2/GSN/CYBB/HLA-DQB2/ATP6V0B/LDLR/ACTG1/CTLA4/FCGR1A/HLA-H/CD207/HLA-G/RAB32/CAMK2A/RAB13/UBB/CD74/FMNL1/AMOT/HIP1R/AMBRA1/ATP6V0C/HBA2/RPS27A/MPEG1/PICK1/HLA-DPA1/CORO1A/HLA-E/CACNG3/UBA52/SCARF1/TLR2/ABCA1/HLA-DRA/HVCN1/AP2S1/LRP1/SNAP23/RALA/STX12/TAP1/WNT7A/TLR6/RAPGEF1/RAB11FIP3/CUBN/CAMK2G/SYT11/RAC2/VAMP3/RAB38/MPO/CYBA/VIM/UVRAG/HLA-DQA2/HEATR5B/RAPGEF2/RAB23/CD2AP/LAMP1/PIK3C3/CAMK2D/RAB11FIP4/HBB/COLEC12/HLA-DPB1/ARF6/PIK3R4/LMBRD1/RAB34/FZD5/NCF1/KIAA1107/EHD3/TYRP1/WAS/HLA-DRB1/AMELX/DLG4/RAB12	99
CC	GO:0032587	ruffle membrane	37/4919	94/19717	0.001411	0.01573	0.01277	RASGRP2/RAC1/TIRAP/CORO1C/KSR1/PDE4A/NF2/FGD2/IFIT5/PLEKHA1/SRC/PSD4/TIAM1/ARHGEF2/PDXP/PAK1/SH3YL1/RPS3/HIP1R/EPS8L2/MTMR9/EZR/CLASP2/AIF1/CFL1/EEF1A1/PSD3/EPB41L5/ARF4/TESC/PACSIN1/TPM1/AIF1L/APC/PPP1R9B/PIP5K1A/SPATA13	37
CC	GO:0035579	specific granule membrane	36/4919	91/19717	0.001463	0.01608	0.01305	PLAUR/OLR1/LAIR1/CEACAM1/ATP11A/ATP8B4/CYBB/PLAU/AGPAT2/SLC2A3/TMEM63A/P2RX1/SLC27A2/CD33/CD177/CD47/TOM1/HVCN1/SNAP23/TMEM30A/FPR2/CLEC4D/C3AR1/FCAR/CYBA/CKAP4/TNFRSF1B/ALDH3B1/HMOX2/CLEC5A/LAMTOR2/RAB37/STOM/SLCO4C1/ORMDL3/CD93	36
CC	GO:0042581	specific granule	57/4919	160/19717	0.001635	0.01771	0.01438	QPCT/PTPN6/LRG1/PLAUR/CYFIP1/OLR1/LAIR1/CANT1/HPSE/TIMP2/CEACAM1/ATP11A/ATP8B4/NEU1/CYBB/PLAU/AGPAT2/SLC2A3/TMEM63A/P2RX1/GGH/SLC27A2/LYZ/CD33/TCN1/CD177/TOLLIP/QSOX1/CD47/SPTAN1/TOM1/HVCN1/SNAP23/CTSD/TMEM30A/ARG1/RAB27A/FPR2/CLEC4D/C3AR1/CTSZ/FCAR/CYBA/CKAP4/TNFRSF1B/ALDH3B1/HMOX2/CLEC5A/CNN2/LAMTOR2/DEFA4/RAB37/STOM/NIT2/SLCO4C1/ORMDL3/CD93	57
CC	GO:0045121	membrane raft	102/4919	315/19717	0.001672	0.01786	0.01449	FURIN/SDC4/ICAM1/FAIM2/HCK/EPHB1/HK1/PTGIS/OLR1/HPSE/TUBA1B/GPC1/CORO1C/KIF18A/PTCH1/TNF/LRP8/AKAP5/CD1A/ADTRP/ANXA2/MYADM/RANGRF/TUBB/SRC/HMOX1/P2RX1/CFLAR/CLIP3/BTK/HTR2A/SDCBP/BST2/KCNE3/MYOF/PPT1/CD177/KCNA3/ADD3/EFNB1/SLC2A4/PIKFYVE/S1PR1/ATP1B1/LRP4/FAS/RGS19/PTPRC/EZR/ITGA1/LTB4R/RFTN1/LAT/TLR2/ABCA1/FLOT1/S100A10/PPP2CA/PI4K2A/ATP2B4/CTSD/THY1/CD19/STX12/GNAI2/CNR1/NTSR1/TLR6/VDAC1/SLC38A9/PARK7/ATP1B3/ABCB4/CD48/SLC25A5/CRK/BSG/BIRC3/CTNNA1/ASAH2/TRAF2/CARD11/PRNP/TNFRSF1B/F2R/LAMTOR4/CHRNA3/LRP6/LAMTOR2/INSR/AHNAK/DLL1/STOM/RGMB/HAS2/RTN4R/MAPK1/TRPC5/ZAP70/ADD2/TFPI/FYN	102
CC	GO:1905369	endopeptidase complex	27/4919	64/19717	0.001848	0.01925	0.01562	PSMD8/VCP/PSMD1/PSMD2/PSMF1/RAD23B/PSMD9/PSMA5/PSMB7/UBE3A/RAD23A/PSMD5/UCHL5/PSME2/ZFAND2A/PSMB5/ZFAND2B/PSMB4/PSMA3/PAAF1/PSMD10/PSMB1/PSMD7/PSMB3/DNAJB2/PSMC5/PSMD11	27
CC	GO:0098857	membrane microdomain	102/4919	316/19717	0.001873	0.01925	0.01562	FURIN/SDC4/ICAM1/FAIM2/HCK/EPHB1/HK1/PTGIS/OLR1/HPSE/TUBA1B/GPC1/CORO1C/KIF18A/PTCH1/TNF/LRP8/AKAP5/CD1A/ADTRP/ANXA2/MYADM/RANGRF/TUBB/SRC/HMOX1/P2RX1/CFLAR/CLIP3/BTK/HTR2A/SDCBP/BST2/KCNE3/MYOF/PPT1/CD177/KCNA3/ADD3/EFNB1/SLC2A4/PIKFYVE/S1PR1/ATP1B1/LRP4/FAS/RGS19/PTPRC/EZR/ITGA1/LTB4R/RFTN1/LAT/TLR2/ABCA1/FLOT1/S100A10/PPP2CA/PI4K2A/ATP2B4/CTSD/THY1/CD19/STX12/GNAI2/CNR1/NTSR1/TLR6/VDAC1/SLC38A9/PARK7/ATP1B3/ABCB4/CD48/SLC25A5/CRK/BSG/BIRC3/CTNNA1/ASAH2/TRAF2/CARD11/PRNP/TNFRSF1B/F2R/LAMTOR4/CHRNA3/LRP6/LAMTOR2/INSR/AHNAK/DLL1/STOM/RGMB/HAS2/RTN4R/MAPK1/TRPC5/ZAP70/ADD2/TFPI/FYN	102
CC	GO:0035577	azurophil granule membrane	25/4919	58/19717	0.001877	0.01925	0.01562	ACPP/CD68/FPR1/SURF4/BRI3/HLA-H/BST2/RAB3D/SNAP29/ATP6V0C/PIGR/NFAM1/PRCP/TOM1/TMEM30A/C3AR1/CKAP4/LAMP1/SYNGR1/GLIPR1/RAB37/VNN1/MANBA/STOM/SLCO4C1	25
CC	GO:0000940	condensed chromosome outer kinetochore	9/4919	14/19717	0.002113	0.0211	0.01713	CENPF/SKA1/BUB1B/SKA3/BUB1/PLK1/CCNB1/NDC80/BOD1	9
CC	GO:0005767	secondary lysosome	9/4919	14/19717	0.002113	0.0211	0.01713	SQSTM1/NCF4/MAP1LC3A/FTL/NCOA4/FTH1/LAMP1/PIK3C3/NCF1	9
CC	GO:0005876	spindle microtubule	25/4919	59/19717	0.002496	0.02427	0.0197	AURKB/SKA1/KIF4A/CDK1/BIRC5/AURKA/SKA3/NUSAP1/KIF18A/KIF11/PLK1/PSRC1/CENPE/NUMA1/BOD1/CLASP2/KLHL21/TUBG2/PRC1/TUBG1/KLHL22/MAP9/ARL3/CDC16/TUBGCP3	25
CC	GO:0016607	nuclear speck	124/4919	397/19717	0.002508	0.02427	0.0197	E2F7/DUSP10/BNIP3L/U2AF1/DYRK3/PRPF40B/C12orf57/PSPC1/BMP2K/SFPQ/MAML1/PQBP1/HSPA1A/CDC25C/GADD45A/PIAS3/POMP/POLDIP3/CWC25/LMNA/NR3C1/MAML2/USP36/RMI2/LUC7L3/TENM1/DGKZ/SMU1/PPIH/RNPS1/EFTUD2/GLIS2/DOCK1/SRSF4/SNRNP40/STK19/TRIM22/GCAT/LHPP/NAMPT/PIAS1/ALKBH5/TIMM50/TFIP11/ATOH8/SART1/HSF4/PRPF31/THAP7/PNISR/THOC3/SNURF/LIMK1/RBM4B/AKAP17A/SUMO1/PPP1R16B/ITPKC/RSRC1/BASP1/DDX17/SF3B2/TAB1/TOPORS/U2AF1L4/VPS72/HIF3A/GTF2H2/HOXB2/EPAS1/WBP4/PIAS2/ATPAF2/DDX42/SETD1B/OIP5/FIBP/SDCBP2/TBXA2R/ZNF830/PRPF19/CNOT7/CKAP4/IFI16/PPP1R8/MAGOH/CDYL/YLPM1/PRPF3/CDC5L/CCNL2/EAF1/FBXL4/CLK3/RBM11/PASD1/PNN/RFXAP/GRK5/TUT1/ZNF638/ELL/BAZ2A/FNBP4/CPSF6/ARHGAP18/EAF2/CDC40/MBD1/RBM27/OGG1/WRN/SMC5/PIP5K1A/PLCB1/CWC22/CLK2/PHF5A/SYF2/PDX1/YTHDC1/BARD1/KAT6A/DPP3	124
CC	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	46/4919	126/19717	0.002525	0.02427	0.0197	ANPEP/SURF4/GORASP1/HMGB1/HSPA5/MCFD2/SPPL3/MGAT4B/F5/STX5/CNIH2/WHAMMP3/NUCB1/TMED3/BCAP31/TBC1D20/LRPAP1/TMED9/TAP1/CHP1/GBF1/TMED10/PIEZO1/PRRG4/CTSZ/TMED5/IST1/LMAN2/TMED4/NUCB2/YIF1A/YIF1B/RAB2A/DICER1/CA4/RAB37/MAN1A1/STK17B/WHAMM/TMED1/RGMB/COPG2/TMED6/TRAPPC12/CCDC115/RAB1B	46
CC	GO:0098589	membrane region	104/4919	328/19717	0.003194	0.03032	0.02461	FURIN/SDC4/ICAM1/FAIM2/HCK/EPHB1/HK1/PTGIS/OLR1/HPSE/TUBA1B/GPC1/CORO1C/KIF18A/PTCH1/TNF/LRP8/AKAP5/CD1A/ADTRP/ANXA2/MYADM/RANGRF/TUBB/SRC/HMOX1/P2RX1/CFLAR/CLIP3/BTK/HTR2A/SDCBP/BST2/KCNE3/MYOF/PPT1/CD177/KCNA3/ADD3/EFNB1/SLC2A4/PIKFYVE/S1PR1/ATP1B1/LRP4/FAS/RGS19/PTPRC/EZR/ITGA1/LTB4R/RFTN1/LAT/TLR2/ABCA1/FLOT1/S100A10/PPP2CA/PI4K2A/ATP2B4/CTSD/THY1/CD19/STX12/GNAI2/CNR1/NTSR1/TLR6/CD46/VDAC1/SLC38A9/PARK7/ATP1B3/ABCB4/CD48/SLC25A5/CRK/BSG/BIRC3/CTNNA1/ASAH2/TRAF2/CARD11/PRNP/TNFRSF1B/F2R/LAMTOR4/CHRNA3/LRP6/LAMTOR2/INSR/AHNAK/DLL1/STOM/RGMB/HAS2/RTN4R/MAPK1/TRPC5/ZAP70/NUP62/ADD2/TFPI/FYN	104
CC	GO:0042611	MHC protein complex	13/4919	25/19717	0.003286	0.03081	0.02501	HLA-DQB2/HLA-DMA/HLA-H/HLA-G/CD74/HLA-DPA1/HLA-E/HLA-DRA/MR1/HLA-DMB/HLA-DQA2/HLA-DPB1/HLA-DRB1	13
CC	GO:0030667	secretory granule membrane	95/4919	298/19717	0.003928	0.03639	0.02954	CD109/ANPEP/RAB31/ACPP/CD68/FPR1/RAC1/SERPINB6/CYSTM1/PLAUR/OLR1/LAIR1/SIRPA/SURF4/LGALS3/CEACAM1/ATP11A/CD9/BRI3/ATP8B4/CYBB/PLAU/AGPAT2/SLC2A3/HYAL3/ITGAX/HLA-H/TMEM63A/P2RX1/RHOG/MOXD1/SYT4/PAM/FABP5/SLC27A2/BST2/SRI/CD33/CD177/CCDC136/RAB3D/SNAP29/ATP6V0C/TBC1D10C/PHACTR2/PTPRC/PIGR/NFAM1/CD47/TLR2/PRCP/TOM1/HVCN1/CD58/LILRB2/SNAP23/TMEM30A/RAB27A/CD46/FPR2/ENPP4/CLEC4D/C3AR1/TMED10/CD44/CYB5R1/FCAR/CYBA/ATP8B3/RHOF/BSG/CKAP4/LAMP1/SYNGR1/PCSK4/TNFRSF1B/GLIPR1/TYROBP/ALDH3B1/HMOX2/ITGA2B/CLEC5A/LAMTOR2/CA4/RAB37/VNN1/MANBA/ABCA3/STOM/CLCA1/SLCO4C1/PTAFR/DSC1/ORMDL3/CD93	95
CC	GO:0031083	BLOC-1 complex	9/4919	15/19717	0.004116	0.03724	0.03023	BLOC1S6/SNAP47/BLOC1S1/BCAS4/BLOC1S4/PI4K2A/DTNBP1/STX12/SNAPIN	9
CC	GO:0035102	PRC1 complex	9/4919	15/19717	0.004116	0.03724	0.03023	CBX8/PHC3/CBX2/PHC2/PCGF6/PCGF1/CBX7/PCGF5/BMI1	9
CC	GO:0030863	cortical cytoskeleton	42/4919	116/19717	0.004486	0.04012	0.03256	ANLN/RIMS3/PVALB/HIP1/RTKN/NF2/SNX9/GSN/CTTN/WIPF2/MYADM/LANCL2/NUMA1/PLS1/GYPC/HIP1R/SPTBN1/EZR/CORO1A/CFL1/ACTN4/COTL1/FLOT1/SPTAN1/MAEA/CAPZA1/EEF1A1/SHROOM1/WDR1/EPB41L2/KRT19/SHROOM3/CALB2/MYH9/EPB41/UTRN/AKAP13/LASP1/MED28/WAS/DLG4/ACTB	42
CC	GO:0030864	cortical actin cytoskeleton	34/4919	90/19717	0.004688	0.04143	0.03363	ANLN/PVALB/HIP1/RTKN/NF2/SNX9/GSN/CTTN/WIPF2/MYADM/LANCL2/PLS1/HIP1R/SPTBN1/CORO1A/CFL1/COTL1/FLOT1/SPTAN1/MAEA/CAPZA1/EEF1A1/SHROOM1/WDR1/EPB41L2/KRT19/SHROOM3/CALB2/MYH9/UTRN/AKAP13/LASP1/MED28/WAS	34
CC	GO:0000780	condensed nuclear chromosome, centromeric region	13/4919	26/19717	0.005085	0.04444	0.03607	AURKB/CENPA/BUB1B/PMF1/AURKA/BUB1/NUF2/PLK1/CCNB1/NDC80/CENPO/REC8/CENPK	13
CC	GO:0055038	recycling endosome membrane	31/4919	81/19717	0.005403	0.04649	0.03774	SLC1A1/NTRK1/RAC1/RFFL/ZFYVE27/HLA-H/PDLIM4/GRIPAP1/HLA-G/CLIP3/RAB13/MICALL1/NDRG1/SLC9A7/HLA-E/STX12/ACAP1/RAB11FIP3/VAMP3/PLEKHB2/VTI1B/RAB11FIP5/RAB11FIP4/LZTR1/SORCS2/ARF6/ZDHHC2/EHD3/EHD4/RAB12/SLC9A6	31
CC	GO:0071556	integral component of lumenal side of endoplasmic reticulum membrane	14/4919	29/19717	0.005501	0.04649	0.03774	HLA-DQB2/SPPL3/HLA-H/HLA-G/CD74/PKD2/HLA-DPA1/BCAP31/HLA-E/HLA-DRA/HLA-DQA2/CANX/HLA-DPB1/HLA-DRB1	14
CC	GO:0098553	lumenal side of endoplasmic reticulum membrane	14/4919	29/19717	0.005501	0.04649	0.03774	HLA-DQB2/SPPL3/HLA-H/HLA-G/CD74/PKD2/HLA-DPA1/BCAP31/HLA-E/HLA-DRA/HLA-DQA2/CANX/HLA-DPB1/HLA-DRB1	14
CC	GO:0061695	transferase complex, transferring phosphorus-containing groups	83/4919	259/19717	0.005745	0.04802	0.03898	CCNF/CDK1/CDKN1A/CCNG2/CCNA2/CCNB2/CDK5/PFKP/SOCS2/IFIT5/CKS2/CCNB1/SOCS3/PKM/CDK2/IGF1R/ZNFX1/CKS1B/KAT2A/CCNE2/CDK14/PIK3R5/POLR2J3/POLR3H/CDK7/PRKAB2/TAF1L/MAP3K5/CCNT2/SUPT3H/POLR1D/POLD4/PRPSAP2/ULK1/TAF9B/RECQL5/SLA2/TAF6L/TAF10/PRKAG2/INSRR/POLR2I/POLE/MCM3/ERCC2/PEX2/ACVR1C/ACVR2B/RPRD1A/TAF11/CCNK/GTF2H2/POLR2C/GTF2H1/UVRAG/ZNRD1/ZNF768/PHKG2/CCNJ/PIK3C3/DNA2/TAF7/ERN1/TAF6/POLR2M/MNAT1/MAD2L2/INSR/POLR2J/PIK3R4/CCNY/PRPS1/CRCP/GTF2H5/POLR3GL/PFKL/POLR2A/CCNI/CCND1/SESN2/POLR1B/ERCC1/POLE2	83
CC	GO:1902554	serine/threonine protein kinase complex	33/4919	88/19717	0.006018	0.04977	0.0404	CCNF/CDK1/CDKN1A/CCNG2/CCNA2/CCNB2/CDK5/IFIT5/CKS2/CCNB1/CDK2/CKS1B/CCNE2/CDK14/CDK7/CCNT2/ULK1/ERCC2/ACVR1C/ACVR2B/CCNK/GTF2H2/GTF2H1/UVRAG/PHKG2/CCNJ/ERN1/MNAT1/CCNY/GTF2H5/CCNI/CCND1/SESN2	33
CC	GO:0030669	clathrin-coated endocytic vesicle membrane	19/4919	44/19717	0.006181	0.05006	0.04063	HBEGF/FCGR1B/HIP1/CD9/HLA-DQB2/LDLR/FCGR1A/CD207/CD74/HIP1R/HLA-DPA1/HLA-DRA/AP2S1/HLA-DQA2/HLA-DPB1/FZD5/KIAA1107/TYRP1/HLA-DRB1	19
CC	GO:0043596	nuclear replication fork	18/4919	41/19717	0.006184	0.05006	0.04063	TREX1/MCM10/TONSL/CDC45/GINS2/GINS4/ZRANB3/POLD4/TIMELESS/ERCC5/MCM3/PRPF19/CDC5L/ETAA1/PURB/HELB/XPA/TIPIN	18
CC	GO:0014069	postsynaptic density	101/4919	324/19717	0.006284	0.05033	0.04086	SLC16A3/ADORA2A/NTRK2/SIPA1L1/BCL11A/LZTS1/CAMK1/CDK5/PTCH1/SEMA4C/CHMP2B/SYN1/LRP8/AKAP5/SRGAP2/RPS25/NCS1/RPL10A/NETO2/RPS18/RPS27/RPL38/HOMER2/STAT3/SRC/DGKZ/RPL30/TIAM1/HOMER1/ARHGEF2/FABP5/ARRB1/SNAP47/HNRNPA3/CAMK2A/PDE4B/RPL7/CNIH2/RPS13/P2RX6/RPL6/ADD3/DLGAP3/CRTC1/RPS3/HIP1R/NRGN/SH3GL1/PAK3/SYNJ2BP/LRP4/PICK1/RPL23/SPTBN1/RPS19/DLGAP1/CACNG3/DVL1/PKP4/TANC2/SCRIB/DTNBP1/RPL14/TANC1/PSD3/FMR1/DNAJC6/CABP1/SYT11/ADAM22/SAMD14/RPL12/MINK1/LRFN4/DLG5/NLGN4Y/DNM1/LRFN2/PRNP/PTPRS/EPB41/GOPC/CHRNA3/CPEB1/SORCS2/P2RY1/CLSTN3/SYN2/LRRC4C/BCR/PPP1R9B/LIN7C/ARHGAP32/MAPK1/IQSEC3/ADD2/FYN/DLG4/PAK2/PJA2/SHISA7	101
CC	GO:0043202	lysosomal lumen	35/4919	95/19717	0.006577	0.05214	0.04233	SDC4/CD1E/CTSA/NEU4/GLB1/HPSE/GPC1/IFI30/GM2A/NEU1/TPP1/IDS/OGN/IDUA/TXNDC5/ATP13A2/SDC2/CD74/PPT1/MAN2B1/CTSF/CTSB/TCN2/SDC1/GBA/CTSD/GPC2/CUBN/CHID1/GALC/HEXB/GUSB/LIPA/MANBA/FUCA1	35
CC	GO:0045335	phagocytic vesicle	46/4919	132/19717	0.006901	0.05415	0.04396	CDC42EP4/RAB31/ZYX/RAB11FIP1/ATP6V0D1/NCF4/UNC93B1/PLD4/SRGAP2/GSN/CYBB/ATP6V0B/ACTG1/HLA-H/HLA-G/RAB32/FMNL1/AMBRA1/ATP6V0C/MPEG1/CORO1A/HLA-E/TLR2/ABCA1/HVCN1/SNAP23/STX12/TAP1/TLR6/RAPGEF1/SYT11/RAC2/VAMP3/RAB38/MPO/CYBA/VIM/UVRAG/RAB23/LAMP1/PIK3C3/PIK3R4/RAB34/NCF1/WAS/RAB12	46
CC	GO:0042613	MHC class II protein complex	9/4919	16/19717	0.007339	0.05701	0.04627	HLA-DQB2/HLA-DMA/CD74/HLA-DPA1/HLA-DRA/HLA-DMB/HLA-DQA2/HLA-DPB1/HLA-DRB1	9
CC	GO:0044448	cell cortex part	61/4919	184/19717	0.007424	0.05709	0.04634	SAPCD2/GPSM2/ANLN/TNFAIP2/RIMS3/PVALB/ENO1/HIP1/RTKN/CLTB/NF2/SNX9/GSN/CTTN/WIPF2/MYADM/LANCL2/ASPH/NUMA1/MYL12B/PLS1/C2CD2L/GYPC/PKD2/HIP1R/SPTBN1/EZR/CORO1A/CLASP2/CFL1/ACTN4/COTL1/FLOT1/SPTAN1/MAEA/CAPZA1/PPFIA3/EEF1A1/EMD/SHROOM1/CTSZ/WDR1/EPB41L2/KRT19/EXOC6B/ERC2/SHROOM3/CALB2/PHLDB1/MYH9/ACTR1A/ARV1/EPB41/UTRN/AKAP13/CTBP1/LASP1/MED28/WAS/DLG4/ACTB	61
CC	GO:1902911	protein kinase complex	39/4919	109/19717	0.007524	0.05721	0.04644	CCNF/CDK1/CDKN1A/CCNG2/CCNA2/CCNB2/CDK5/IFIT5/CKS2/CCNB1/CDK2/IGF1R/CKS1B/CCNE2/CDK14/CDK7/PRKAB2/MAP3K5/CCNT2/ULK1/PRKAG2/INSRR/ERCC2/ACVR1C/ACVR2B/CCNK/GTF2H2/GTF2H1/UVRAG/PHKG2/CCNJ/ERN1/MNAT1/INSR/CCNY/GTF2H5/CCNI/CCND1/SESN2	39
CC	GO:0005938	cell cortex	96/4919	308/19717	0.007588	0.05721	0.04644	MYO7A/SAPCD2/GPSM2/ANLN/TNFAIP2/GPSM1/NEDD9/TRIP10/MELK/MARCKS/RIMS3/PVALB/ENO1/CORO1C/HIP1/RTKN/CLTB/NF2/SNX9/MYH10/GSN/CTTN/WIPF2/ANXA2/MYADM/LANCL2/ASPH/NUMA1/RHOG/MYL12B/PLS1/C2CD2L/ADD3/GYPC/FMNL1/FAM110C/PKD2/HIP1R/SPTBN1/EZR/CORO1A/CLASP2/WDPCP/CFL1/ACTN4/COTL1/FLOT1/SPTAN1/NCL/MAEA/NRBP1/CAPZA1/PPFIA3/EEF1A1/EMD/CABP1/SHROOM1/CTSZ/WDR1/EPB41L2/MYO9B/PARD6G/KRT19/EXOC6B/RHOF/MICAL3/ERC2/RHOV/PDZD4/SHROOM3/CALB2/RHOU/PHLDB1/BFSP2/TRAF2/MYH9/ACTR1A/ARV1/FER/EPB41/UTRN/PARD6B/AQP7/TRAF6/ARF6/AKAP13/CTBP1/PARD6A/LASP1/RIC8B/ARHGAP32/MED28/CDC42/WAS/DLG4/ACTB	96
CC	GO:0070821	tertiary granule membrane	28/4919	73/19717	0.007672	0.05728	0.04649	SERPINB6/CYSTM1/OLR1/LAIR1/SIRPA/CEACAM1/ATP11A/ATP8B4/CYBB/PLAU/SLC2A3/ITGAX/TMEM63A/CD33/CD177/ATP6V0C/CD47/LILRB2/SNAP23/FPR2/CLEC4D/FCAR/CYBA/CLEC5A/LAMTOR2/STOM/PTAFR/CD93	28
CC	GO:0031300	intrinsic component of organelle membrane	76/4919	237/19717	0.007795	0.05764	0.04679	FURIN/SLC35A2/SGMS1/SFXN1/SCO2/GALNT2/SGMS2/SYN1/TMEM43/TIMM17A/VOPP1/ABCD1/GDAP1/SLC35B1/P2RX1/SYT4/FAR2/CSGALNACT1/SLC27A2/ATP13A2/MICU1/P2RX6/SUN2/TMEM11/FKTN/COX18/SYNJ2BP/BID/PINK1/QSOX1/TBC1D20/SLC35B2/LEMD3/COA3/BAK1/CHCHD6/STX12/CNR1/SLC38A9/PEX2/SYT11/VAMP3/SCO1/ACER2/STX16/ENTPD4/YIF1A/PEX3/ITM2B/YIF1B/LAMP1/SYNGR1/CPT1A/P2RX5/PCSK4/PTPRS/RHOT2/PPOX/ZDHHC9/PEX11A/FUNDC2/UNC50/PCSK5/SLC35B4/SLC25A4/AGK/TMEM201/PEX13/MPC1/COX11/SV2A/SPG7/P2RX7/TRABD2B/MGARP/FUNDC1	76
CC	GO:0099738	cell cortex region	18/4919	42/19717	0.008338	0.06049	0.0491	SAPCD2/GPSM2/ANLN/RIMS3/ENO1/CLTB/NUMA1/MYL12B/PKD2/CLASP2/PPFIA3/CTSZ/EPB41L2/ERC2/PHLDB1/ACTR1A/EPB41/CTBP1	18
CC	GO:1990391	DNA repair complex	18/4919	42/19717	0.008338	0.06049	0.0491	RCOR1/MSH6/ZSWIM7/PMS2P1/TP53BP1/XRCC6/RAD23B/ERCC8/ERCC5/PMS2P5/XRCC1/NHEJ1/CETN2/XPA/ATM/MLH3/ERCC1/PMS1	18
CC	GO:0019898	extrinsic component of membrane	92/4919	295/19717	0.008657	0.06222	0.0505	GNG4/GNA15/FES/HCK/PLAUR/RACGAP1/HIP1/MTMR3/GNG10/PRSS27/PML/SOCS2/ST14/SNX9/KPNA2/SYN1/SYAP1/BLK/UBXN6/ANXA2/SMAD7/FCN1/SRC/SOCS3/BLOC1S6/GRIPAP1/NUMA1/TIAM1/GNAS/GNG7/JAKMIP1/NOA1/PIK3R5/RNF40/PTK6/MICALL1/STXBP5/NUCB1/NMT1/DNAJA3/SGTA/EZR/CYLD/S100A6/STAC3/ULK1/SCRIB/S100A10/FKBP1A/GBA/STAC/AAK1/SLA2/SYTL1/GNAI2/EFCAB7/FMR1/CUBN/CDH26/ATG2B/SNX33/CDH9/ZC3H12A/RGS1/SCUBE1/CTNNA1/PIK3C3/PRNP/EEA1/FER/GML/SYTL3/UMOD/RPH3A/TAMM41/WDR45/CYTH1/GNAQ/PAM16/PIK3R4/APC/VPS13D/D2HGDH/NCF1/GRAMD1A/MITD1/NDUFAF5/CCDC115/GNAT3/CDH5/FYN/DLG4	92
CC	GO:0000781	chromosome, telomeric region	54/4919	161/19717	0.008751	0.06231	0.05058	CDK1/DOT1L/MCM4/MCM5/PML/SIRT6/PPP1CB/BRCA2/FEN1/RAD51/MCM2/CBX5/TP53BP1/PIF1/CDK2/DMC1/ORC1/XRCC6/SUN2/UPF1/MCM7/TERF1/EID3/TFIP11/EZH2/TNKS2/TOX4/ACD/CTC1/THOC3/RNF8/MCM3/CHEK1/RECQL4/POT1/XRCC3/XRCC1/WRAP53/SIRT2/DNA2/SMG6/ATR/CHEK2/WDR82/TINF2/SIRT7/ATM/WRN/SMC5/ORC2/LRWD1/ERCC1/ZBTB48/TERF2	54
CC	GO:0032279	asymmetric synapse	101/4919	328/19717	0.009172	0.06471	0.05252	SLC16A3/ADORA2A/NTRK2/SIPA1L1/BCL11A/LZTS1/CAMK1/CDK5/PTCH1/SEMA4C/CHMP2B/SYN1/LRP8/AKAP5/SRGAP2/RPS25/NCS1/RPL10A/NETO2/RPS18/RPS27/RPL38/HOMER2/STAT3/SRC/DGKZ/RPL30/TIAM1/HOMER1/ARHGEF2/FABP5/ARRB1/SNAP47/HNRNPA3/CAMK2A/PDE4B/RPL7/CNIH2/RPS13/P2RX6/RPL6/ADD3/DLGAP3/CRTC1/RPS3/HIP1R/NRGN/SH3GL1/PAK3/SYNJ2BP/LRP4/PICK1/RPL23/SPTBN1/RPS19/DLGAP1/CACNG3/DVL1/PKP4/TANC2/SCRIB/DTNBP1/RPL14/TANC1/PSD3/FMR1/DNAJC6/CABP1/SYT11/ADAM22/SAMD14/RPL12/MINK1/LRFN4/DLG5/NLGN4Y/DNM1/LRFN2/PRNP/PTPRS/EPB41/GOPC/CHRNA3/CPEB1/SORCS2/P2RY1/CLSTN3/SYN2/LRRC4C/BCR/PPP1R9B/LIN7C/ARHGAP32/MAPK1/IQSEC3/ADD2/FYN/DLG4/PAK2/PJA2/SHISA7	101
CC	GO:0097038	perinuclear endoplasmic reticulum	11/4919	22/19717	0.009776	0.06705	0.05443	CREB3L2/CYBB/OSBP2/CLU/BCAP31/TRIM13/CYBA/GDPD5/DGAT2/OSBPL7/FYN	11
CC	GO:0005871	kinesin complex	22/4919	55/19717	0.009853	0.06705	0.05443	KIF20A/KIF2C/KIF14/KIFC1/KIF4A/KIF15/KIF23/KIF24/KIF20B/KIF1C/KIF18A/YWHAE/KIF11/KLC1/CENPE/KIF4B/KLC3/KIF3C/KLC4/KIF26B/KIF19/KIFC2	22
CC	GO:0032154	cleavage furrow	22/4919	55/19717	0.009853	0.06705	0.05443	KIF20A/CIT/CEP55/RACGAP1/PLCD3/PLK4/NF2/STAMBP/MYH10/SVIL/FSD1/PDXP/PITPNM1/RALA/RAB11FIP3/ICAM2/WDR73/ECT2/MYH9/RAB11FIP4/ARF6/KLHDC8B	22
CC	GO:1904724	tertiary granule lumen	22/4919	55/19717	0.009853	0.06705	0.05443	QPCT/PTPN6/LRG1/CTSH/CYFIP1/CANT1/TIMP2/MMP9/GGH/ALDOC/CST3/LYZ/TCN1/QSOX1/SPTAN1/CTSD/FTH1/ALDOA/HBB/CNN2/PPBP/NIT2	22
CC	GO:0031463	Cul3-RING ubiquitin ligase complex	16/4919	37/19717	0.01136	0.07663	0.0622	KCTD17/KLHL25/KCTD5/TNFAIP1/KLHL3/KLHL9/KLHL21/RNF7/GAN/KCTD13/LZTR1/KLHL22/KLHL7/GLMN/PEF1/KLHL13	16
CC	GO:0031965	nuclear membrane	91/4919	296/19717	0.0134	0.08961	0.07274	NR4A1/SLC16A3/SLC29A2/DTL/LMNB1/SMOX/GAPDH/ALOX5AP/TFPT/MX1/NUP98/TNRC18/LMNB2/TMEM43/CLIC1/LMNA/NUDT1/P2RX1/TMC8/PDE4D/RRP12/DNAJB12/SDCBP/MYOF/PAK1/P2RX6/FAM169A/NUP153/SUN2/DCTN5/IL15RA/TMEM120B/CEP70/TMEM120A/TBC1D20/YEATS4/LEMD3/GCHFR/ALOX5/THAP7/SPAG4/SUMO1/EMD/SEPHS1/ANXA4/POM121C/CLCA2/NUP205/PHLPP1/INA/AEN/BCL2L1/NUP50/TMEM176B/RCC1/SYNE3/NUCB2/SMAD1/RAP1GAP2/LRPPRC/ERN1/P2RX5/PRNP/ZNF224/YBX1/GRK5/ZNF383/GLE1/GNAQ/TXLNG/DTX2/UNC50/NUP93/DDX19A/NUP35/SHISA5/AAAS/TMEM201/ANKRD17/PLCB1/SCRN1/CERS3/MLX/DNAJB2/SYNE2/NUP62/PHF8/P2RX7/LPIN1/SPIN1/SIRT1	91
CC	GO:0031082	BLOC complex	10/4919	20/19717	0.01362	0.09027	0.07327	BLOC1S6/SNAP47/BLOC1S1/BCAS4/BLOC1S4/HPS4/PI4K2A/DTNBP1/STX12/SNAPIN	10
CC	GO:0000109	nucleotide-excision repair complex	7/4919	12/19717	0.01406	0.09241	0.07501	RAD23B/ERCC8/ERCC5/XRCC1/CETN2/XPA/ERCC1	7
CC	GO:0099572	postsynaptic specialization	105/4919	348/19717	0.01482	0.09515	0.07724	SLC16A3/ADORA2A/NTRK2/SIPA1L1/BCL11A/LZTS1/CAMK1/CDK5/PTCH1/SEMA4C/CHMP2B/KPNA2/SYN1/LRP8/AKAP5/SRGAP2/RPS25/CHRNA10/NCS1/RPL10A/NETO2/RPS18/RPS27/RPL38/HOMER2/STAT3/SRC/DGKZ/RPL30/TIAM1/HOMER1/ARHGEF2/FABP5/ARRB1/SNAP47/HNRNPA3/CAMK2A/PDE4B/RPL7/CNIH2/RPS13/P2RX6/RPL6/ADD3/DLGAP3/CRTC1/RPS3/HIP1R/NRGN/SH3GL1/PAK3/SYNJ2BP/LRP4/PICK1/RPL23/SPTBN1/RPS19/DLGAP1/CACNG3/DVL1/PKP4/TANC2/SCRIB/DTNBP1/RPL14/TANC1/PSD3/CHRNA1/FMR1/DNAJC6/CABP1/SYT11/ADAM22/SAMD14/RPL12/MINK1/LRFN4/DLG5/NLGN4Y/DNM1/LRFN2/PRNP/PTPRS/KCND3/EPB41/GOPC/CHRNA3/CPEB1/SORCS2/P2RY1/CLSTN3/SYN2/LRRC4C/BCR/PPP1R9B/LIN7C/ARHGAP32/MAPK1/IQSEC3/ADD2/FYN/DLG4/PAK2/PJA2/SHISA7	105
CC	GO:0018995	host	27/4919	73/19717	0.01485	0.09515	0.07724	TOP2A/IFIT1/SEC13/GBP2/KPNA2/NUP98/UBB/AXL/NUP153/RPS27A/UBA52/PI4K2A/NUP88/FMR1/KPNA3/POM121C/NUP205/RAE1/SCO1/NUP50/CNOT7/NUP93/NUP35/AAAS/GBP4/NUP62/SEH1L	27
CC	GO:0043657	host cell	27/4919	73/19717	0.01485	0.09515	0.07724	TOP2A/IFIT1/SEC13/GBP2/KPNA2/NUP98/UBB/AXL/NUP153/RPS27A/UBA52/PI4K2A/NUP88/FMR1/KPNA3/POM121C/NUP205/RAE1/SCO1/NUP50/CNOT7/NUP93/NUP35/AAAS/GBP4/NUP62/SEH1L	27
CC	GO:0030134	COPII-coated ER to Golgi transport vesicle	33/4919	93/19717	0.01503	0.09553	0.07754	SEC13/YIPF5/SEC24D/MCFD2/HLA-DQB2/F5/STX5/HLA-H/SEC16A/HLA-G/CNIH2/CD74/TMED3/HLA-DPA1/HLA-E/HLA-DRA/TMED9/TMED10/CTSZ/TMED5/LMAN2/HLA-DQA2/TMED4/YIF1A/YIF1B/VTI1B/HLA-DPB1/TMED1/TMED6/PEF1/HLA-DRB1/SREBF2/USO1	33
CC	GO:0000315	organellar large ribosomal subunit	22/4919	57/19717	0.01563	0.09725	0.07894	MRPL37/MRPL28/MRPL51/MRPL22/MRPL18/NSUN4/C12orf65/MRPL20/MRPL50/MRPL36/MRPL35/MRPL27/MRPL15/MRPL34/MRPL13/MRPL10/MRPL54/MRPL2/MRPL39/MRPL43/MRPL48/MALSU1	22
CC	GO:0005762	mitochondrial large ribosomal subunit	22/4919	57/19717	0.01563	0.09725	0.07894	MRPL37/MRPL28/MRPL51/MRPL22/MRPL18/NSUN4/C12orf65/MRPL20/MRPL50/MRPL36/MRPL35/MRPL27/MRPL15/MRPL34/MRPL13/MRPL10/MRPL54/MRPL2/MRPL39/MRPL43/MRPL48/MALSU1	22
CC	GO:0005657	replication fork	26/4919	70/19717	0.01568	0.09725	0.07894	BCL6/TREX1/UHRF1/MCM10/UBE2B/TONSL/TP53BP1/CDC45/PIF1/GINS2/GINS4/ZRANB3/RFC2/POLD4/TIMELESS/ERCC5/MCM3/XRCC3/PRPF19/CDC5L/ETAA1/PURB/HELB/XPA/WRN/TIPIN	26
CC	GO:0034399	nuclear periphery	44/4919	131/19717	0.01624	0.09993	0.08111	CENPF/KIF4A/LMNB1/UHRF1/PSPC1/TGFB1I1/SFPQ/PML/SMC3/CENPW/NUP98/LMNB2/LMNA/TENM1/NUMA1/NARF/KIF4B/MORC2/ATF4/NUP153/SATB1/ATXN1/YEATS4/CFL1/ERCC8/ALOX5/MAEA/PRR14/ZNF326/NUP205/CEBPB/VIM/ZNF703/CLIC4/PIAS4/CHMP1A/ATF7/NUP93/SMC1A/MBD1/TINF2/NUP35/OGG1/PHF5A	44
CC	GO:0000313	organellar ribosome	31/4919	87/19717	0.01695	0.1016	0.08248	MRPL37/MRPL28/MRPL51/MRPS36/MRPL22/MRPL18/MRPS5/MRPS18C/MRPS11/NSUN4/C12orf65/MRPS6/MRPL20/MRPL50/MRPL36/MRPS2/MRPL35/MRPL27/MRPL15/MRPL34/MRPS14/MRPL13/MTG1/MRPL10/MRPL54/DAP3/MRPL2/MRPL39/MRPL43/MRPL48/MALSU1	31
CC	GO:0005761	mitochondrial ribosome	31/4919	87/19717	0.01695	0.1016	0.08248	MRPL37/MRPL28/MRPL51/MRPS36/MRPL22/MRPL18/MRPS5/MRPS18C/MRPS11/NSUN4/C12orf65/MRPS6/MRPL20/MRPL50/MRPL36/MRPS2/MRPL35/MRPL27/MRPL15/MRPL34/MRPS14/MRPL13/MTG1/MRPL10/MRPL54/DAP3/MRPL2/MRPL39/MRPL43/MRPL48/MALSU1	31
CC	GO:0005639	integral component of nuclear inner membrane	8/4919	15/19717	0.01705	0.1016	0.08248	TMEM43/P2RX1/P2RX6/SUN2/LEMD3/P2RX5/TMEM201/P2RX7	8
CC	GO:0031229	intrinsic component of nuclear inner membrane	8/4919	15/19717	0.01705	0.1016	0.08248	TMEM43/P2RX1/P2RX6/SUN2/LEMD3/P2RX5/TMEM201/P2RX7	8
CC	GO:0019005	SCF ubiquitin ligase complex	24/4919	64/19717	0.01746	0.1033	0.08385	CCNF/FBXL19/SPSB1/AMN1/CKS2/FBXL18/CKS1B/FBXL14/FBXO48/FBXO27/FBXO31/FBXL8/FBXW11/CUL5/SPSB2/RNF7/BTRC/FBXL4/FBXO9/FBXL15/FBXL20/FBXO44/CUL4A/FBXO4	24
CC	GO:0005884	actin filament	38/4919	111/19717	0.01776	0.1042	0.08462	SMTN/SH2B2/HCK/RAC1/CTTN/WIPF2/ACTG1/MYO5A/SRC/PDLIM4/CORO1B/PLS1/PAK1/PKD2/AMOT/PDLIM7/DNAJA3/EZR/CORO1A/AIF1/TWF2/DUSP22/COTL1/TPM2/RAC2/WDR1/MYO9B/CD2AP/TPM1/AIF1L/MYO18B/AKAP13/PSTPIP2/WAS/FMN1/FYN/RAC3/SPECC1L	38
CC	GO:0031527	filopodium membrane	9/4919	18/19717	0.01904	0.1109	0.09004	ITGA3/NF2/HLA-G/TBC1D10C/VASP/FZD9/UTRN/ARF6/SYNE2	9
CC	GO:0000242	pericentriolar material	10/4919	21/19717	0.02028	0.1173	0.09517	DYRK3/CEP152/TUBE1/TNKS2/TUBG2/BBS9/WDR60/CEP192/NEK1/TUBG1	10
CC	GO:0080008	Cul4-RING E3 ubiquitin ligase complex	14/4919	33/19717	0.02087	0.1198	0.09723	DTL/DCAF12/DDB2/DET1/ERCC8/DCAF10/DCAF5/DCAF4/DCAF15/RNF7/DCAF17/CUL4A/GLMN/CRBN	14
CC	GO:0098984	neuron to neuron synapse	104/4919	350/19717	0.02334	0.1308	0.1062	SLC16A3/ADORA2A/NTRK2/SIPA1L1/BCL11A/LZTS1/CAMK1/CDK5/PTCH1/YWHAZ/SEMA4C/CHMP2B/SYN1/LRP8/AKAP5/SRGAP2/RPS25/NCS1/RPL10A/NETO2/RPS18/RPS27/RPL38/HOMER2/STAT3/SRC/DGKZ/RPL30/TIAM1/HOMER1/ARHGEF2/FABP5/ARRB1/SNAP47/HNRNPA3/CAMK2A/PDE4B/RPL7/CNIH2/RPS13/P2RX6/RPL6/ADD3/DLGAP3/CRTC1/RPS3/HIP1R/NRGN/SH3GL1/PAK3/SYNJ2BP/LRP4/PICK1/RPL23/SPTBN1/RPS19/DLGAP1/CACNG3/DVL1/PKP4/TANC2/SCRIB/DTNBP1/RPL14/TANC1/NTSR1/PSD3/FMR1/DNAJC6/CABP1/SYT11/ADAM22/SAMD14/RPL12/MINK1/LRFN4/DLG5/NLGN4Y/DNM1/LRFN2/PRNP/PTPRS/EPB41/GOPC/CHRNA3/CPEB1/AKAP7/SORCS2/P2RY1/CLSTN3/SYN2/LRRC4C/BCR/PPP1R9B/LIN7C/ARHGAP32/MAPK1/IQSEC3/ADD2/FYN/DLG4/PAK2/PJA2/SHISA7	104
CC	GO:0044798	nuclear transcription factor complex	63/4919	201/19717	0.02341	0.1308	0.1062	VDR/E2F7/E2F8/PPARG/GTF3C4/E2F2/KLF4/CBFB/TLE4/SFPQ/THRA/ASCL1/E2F1/MXD3/STAT3/POU2F1/MED4/KAT2A/ATF4/BRF2/TCF7L2/CARM1/GTF3C2/CDK7/TAF1L/SUPT3H/TLE3/TFDP2/TAF9B/DDIT3/TAF6L/PTOV1/TAF10/RXRA/WWOX/SOX8/JUN/ERCC2/TAF11/GTF2H2/CEBPB/SOX11/YAP1/GTF2H1/TAF1A/TAF7/TAF6/GTF3C6/BDP1/MNAT1/TAF1D/MAX/GTF2H5/PBX1/POU2AF1/FOS/PPARD/MXI1/RARA/GEMIN5/LDB1/ERCC1/NFYB	63
CC	GO:0005667	transcription factor complex	108/4919	365/19717	0.02383	0.1308	0.1062	VDR/NR4A1/E2F7/E2F8/PMF1/NR4A3/PPARG/GTF3C4/E2F2/KLF4/RCOR1/SPI1/CBFB/TLE4/SFPQ/ARNTL2/THRA/ASCL1/ATF5/E2F1/SKI/TEAD3/MXD3/TLE2/STAT3/SNF8/SMAD7/BARX2/NKX2-1/ALX1/POU2F1/LIMD1/CDK2/MED4/WWTR1/KAT2A/RBPJ/ATF4/XRCC6/ZFHX3/SSBP3/LMO4/SMAD6/RUNX2/FIGLA/BRF2/TCF7L2/CARM1/GTF3C2/CDK7/TAF1L/SUPT3H/TLE3/TFDP2/TAF9B/PBX2/DDIT3/TAF6L/PTOV1/TAF10/RXRA/WWOX/SOX8/NAA16/JUN/RCOR3/MEF2B/ERCC2/TAF11/GTF2H2/EPAS1/CEBPB/SOX11/RBL2/ARNTL/YY2/YAP1/GTF2H1/TAF1A/POU3F1/SMAD1/TAF7/ABT1/TAF6/GTF3C6/BDP1/MNAT1/TAF1D/HOXA11/MAX/CTBP1/HDAC9/GTF2H5/PBX1/POU2AF1/FOS/PPARD/TEAD4/ARNT2/MXI1/RARA/GEMIN5/ZFPM1/SRA1/LDB1/ERCC1/NFYB/GCM1	108
CC	GO:0000782	telomere cap complex	7/4919	13/19717	0.02398	0.1308	0.1062	XRCC6/TERF1/ACD/CTC1/POT1/TINF2/TERF2	7
CC	GO:0000783	nuclear telomere cap complex	7/4919	13/19717	0.02398	0.1308	0.1062	XRCC6/TERF1/ACD/CTC1/POT1/TINF2/TERF2	7
CC	GO:0001741	XY body	7/4919	13/19717	0.02398	0.1308	0.1062	ESCO2/UBE2A/PBX4/PLK4/UBE2B/SUMO1/DMRTC2	7
CC	GO:1990023	mitotic spindle midzone	7/4919	13/19717	0.02398	0.1308	0.1062	AURKB/KIF20B/KIF18A/CTTN/CENPE/NUMA1/MAP9	7
CC	GO:0005881	cytoplasmic microtubule	25/4919	69/19717	0.02425	0.1313	0.1066	KIF2C/GTSE1/TUBA1B/REEP2/KIF18A/TTC30A/CKAP2/MAPRE2/NUMA1/RAB3D/ENKD1/TUBGCP2/CYLD/CLASP2/TUBG2/SS18/MID1/TUBG1/SERP1/FAM161B/APC/ODF3L2/MAP9/ARL3/BCAS3	25
CC	GO:0031256	leading edge membrane	54/4919	170/19717	0.02636	0.1417	0.115	RASGRP2/ADORA2A/RAC1/TIRAP/CORO1C/KSR1/PDE4A/NF2/AKAP5/FGD2/ANK1/IFIT5/PLEKHA1/DOCK8/SRC/PSD4/TIAM1/ARHGEF2/SCIMP/PDXP/PAK1/SH3YL1/ATF4/RPS3/HIP1R/EPS8L2/SPTBN1/MTMR9/EZR/CLASP2/VASP/AIF1/CFL1/PLXND1/THY1/EEF1A1/PSD3/EPB41L5/CD44/PIEZO1/GABRG2/ARF4/KCNC4/TESC/PACSIN1/INSR/TPM1/AIF1L/APC/PPP1R9B/PIP5K1A/SYNE2/SPATA13/SHISA7	54
CC	GO:0090575	RNA polymerase II transcription factor complex	52/4919	163/19717	0.02666	0.1419	0.1152	VDR/E2F7/E2F8/PPARG/E2F2/CBFB/TLE4/SFPQ/THRA/ASCL1/E2F1/MXD3/STAT3/POU2F1/MED4/KAT2A/ATF4/TCF7L2/CARM1/CDK7/TAF1L/SUPT3H/TLE3/TFDP2/TAF9B/DDIT3/TAF6L/TAF10/RXRA/WWOX/JUN/ERCC2/TAF11/GTF2H2/CEBPB/YAP1/GTF2H1/TAF7/TAF6/MNAT1/MAX/GTF2H5/PBX1/POU2AF1/FOS/PPARD/MXI1/RARA/GEMIN5/LDB1/ERCC1/NFYB	52
CC	GO:0044453	nuclear membrane part	8/4919	16/19717	0.02675	0.1419	0.1152	TMEM43/P2RX1/P2RX6/SUN2/LEMD3/P2RX5/TMEM201/P2RX7	8
CC	GO:0032592	integral component of mitochondrial membrane	26/4919	73/19717	0.02728	0.1428	0.1159	SFXN1/SCO2/TIMM17A/GDAP1/MICU1/TMEM11/COX18/SYNJ2BP/BID/PINK1/COA3/BAK1/CHCHD6/CNR1/SCO1/CPT1A/RHOT2/PPOX/FUNDC2/SLC25A4/AGK/MPC1/COX11/SPG7/MGARP/FUNDC1	26
CC	GO:0045334	clathrin-coated endocytic vesicle	23/4919	63/19717	0.0273	0.1428	0.1159	HBEGF/FCGR1B/MYO1E/HIP1/CD9/CLTB/HLA-DQB2/LDLR/CTLA4/FCGR1A/CD207/CD74/HIP1R/HLA-DPA1/HLA-DRA/AP2S1/HLA-DQA2/HLA-DPB1/LMBRD1/FZD5/KIAA1107/TYRP1/HLA-DRB1	23
CC	GO:0043073	germ cell nucleus	9/4919	19/19717	0.02832	0.1471	0.1194	AURKA/HSPA2/MARCKS/TRIP13/TOPBP1/ACTRT3/REC8/TCFL5/MLH3	9
CC	GO:0098562	cytoplasmic side of membrane	56/4919	178/19717	0.02896	0.1472	0.1195	GNG4/GEM/GNA15/FES/HCK/PTPN7/RACGAP1/DNAJA1/HIP1/GNG10/SNX9/SYAP1/AKAP5/GM2A/BLK/ANK1/PTPN1/SPPL3/SRC/TIAM1/GNAS/GNG7/C2CD2L/PKD2/PTPN4/PTK6/PTPRC/EZR/CYLD/S100A6/RASA3/STAC3/PKP4/LITAF/FKBP1A/STAC/GNAI2/NTSR1/EEF1A1/EPM2AIP1/RGS1/EEF1A2/TRAF2/RPS28/FER/LDLRAP1/EPB41/CYTH1/GNAQ/ACP1/TRAF6/D2HGDH/GRAMD1A/GNAT3/FYN/DLG4	56
CC	GO:0016460	myosin II complex	10/4919	22/19717	0.02903	0.1472	0.1195	MYH10/MYL1/LIMCH1/MYBPC3/MYH7/MYH4/MYL6B/MYH9/MYOM1/MYH6	10
CC	GO:0032982	myosin filament	10/4919	22/19717	0.02903	0.1472	0.1195	MYH10/ACTG2/MYBPC3/MYH7B/MYH7/MYH4/MYH9/MYOM1/MYH6/MYBPC2	10
CC	GO:0005814	centriole	45/4919	139/19717	0.02909	0.1472	0.1195	CCNF/STIL/TOP2A/AURKA/CEP55/WDR62/KIF24/PLK4/HSPA1A/PLK2/ODF2/PLK1/CENPJ/WDR34/FGFR1OP/CAPG/CCDC146/NEURL4/POC1A/HTT/NUBP1/MDM1/CEP152/SFI1/CEP19/TOPORS/CEP192/TSGA10/C10orf90/ALMS1/HSPA6/WRAP73/SIRT2/TSKS/ACTR1A/TUBG1/CETN2/CETN3/AGBL2/HERC2/STARD9/CEP89/CCHCR1/MPHOSPH9/TUBGCP3	45
CC	GO:0031201	SNARE complex	18/4919	47/19717	0.02948	0.1472	0.1195	STX11/STX5/BLOC1S6/SNAP47/SNAP29/STXBP5/STX1B/STX19/SNAP23/STX12/VAMP3/STX16/NAPB/VTI1B/STX2/DOC2B/SYN2/NAPG	18
CC	GO:0031519	PcG protein complex	18/4919	47/19717	0.02948	0.1472	0.1195	PHF19/ASXL2/RYBP/BAP1/CBX8/PHC3/EED/EZH2/CBX2/PHC2/ASXL1/PCGF6/PCGF1/CBX7/YY2/PCGF5/BMI1/SIRT1	18
CC	GO:0044215	other organism	27/4919	77/19717	0.03035	0.1487	0.1207	TOP2A/IFIT1/SEC13/GBP2/KPNA2/NUP98/UBB/AXL/NUP153/RPS27A/UBA52/PI4K2A/NUP88/FMR1/KPNA3/POM121C/NUP205/RAE1/SCO1/NUP50/CNOT7/NUP93/NUP35/AAAS/GBP4/NUP62/SEH1L	27
CC	GO:0044216	other organism cell	27/4919	77/19717	0.03035	0.1487	0.1207	TOP2A/IFIT1/SEC13/GBP2/KPNA2/NUP98/UBB/AXL/NUP153/RPS27A/UBA52/PI4K2A/NUP88/FMR1/KPNA3/POM121C/NUP205/RAE1/SCO1/NUP50/CNOT7/NUP93/NUP35/AAAS/GBP4/NUP62/SEH1L	27
CC	GO:0044217	other organism part	27/4919	77/19717	0.03035	0.1487	0.1207	TOP2A/IFIT1/SEC13/GBP2/KPNA2/NUP98/UBB/AXL/NUP153/RPS27A/UBA52/PI4K2A/NUP88/FMR1/KPNA3/POM121C/NUP205/RAE1/SCO1/NUP50/CNOT7/NUP93/NUP35/AAAS/GBP4/NUP62/SEH1L	27
CC	GO:0031093	platelet alpha granule lumen	24/4919	67/19717	0.03085	0.1502	0.1219	VEGFA/PDGFA/TEX264/PROS1/SERPINE1/F5/CLU/TGFB3/CFD/QSOX1/ACTN4/A2M/FERMT3/TIMP1/SRGN/SERPING1/ALDOA/VTI1B/ISLR/PPBP/OLA1/TGFB1/PDGFB/VEGFC	24
CC	GO:0031091	platelet alpha granule	31/4919	91/19717	0.03213	0.1554	0.1261	CD109/VEGFA/PDGFA/TEX264/CD9/PROS1/SERPINE1/F5/CLU/VPS33B/TGFB3/CFD/THBS2/PHACTR2/QSOX1/ACTN4/A2M/FERMT3/TIMP1/CYB5R1/SRGN/SERPING1/ALDOA/VTI1B/ITGA2B/ISLR/PPBP/OLA1/TGFB1/PDGFB/VEGFC	31
CC	GO:0098573	intrinsic component of mitochondrial membrane	26/4919	74/19717	0.03233	0.1554	0.1261	SFXN1/SCO2/TIMM17A/GDAP1/MICU1/TMEM11/COX18/SYNJ2BP/BID/PINK1/COA3/BAK1/CHCHD6/CNR1/SCO1/CPT1A/RHOT2/PPOX/FUNDC2/SLC25A4/AGK/MPC1/COX11/SPG7/MGARP/FUNDC1	26
CC	GO:0019897	extrinsic component of plasma membrane	52/4919	165/19717	0.03323	0.1587	0.1288	GNG4/GNA15/FES/HCK/RACGAP1/HIP1/GNG10/PRSS27/ST14/SNX9/KPNA2/SYAP1/BLK/ANXA2/SMAD7/FCN1/SRC/NUMA1/TIAM1/GNAS/GNG7/PTK6/STXBP5/DNAJA3/CYLD/S100A6/STAC3/SCRIB/S100A10/STAC/AAK1/SYTL1/GNAI2/FMR1/CUBN/CDH26/CDH9/RGS1/SCUBE1/CTNNA1/EEA1/FER/SYTL3/CYTH1/GNAQ/APC/D2HGDH/GRAMD1A/GNAT3/CDH5/FYN/DLG4	52
CC	GO:0005652	nuclear lamina	6/4919	11/19717	0.03395	0.1612	0.1308	LMNB1/LMNB2/LMNA/NARF/PRR14/NUP35	6
CC	GO:0055037	recycling endosome	55/4919	176/19717	0.03416	0.1612	0.1308	ABCG1/SLC1A1/NTRK1/RAC1/RAB11FIP1/RFFL/TFRC/ATP11A/GPR161/TNF/ZFYVE27/SNF8/SORL1/MYO5A/HLA-H/PDLIM4/GRIPAP1/ATG9A/HLA-G/CLIP3/RAB13/VPS33B/MICALL1/AQP2/NDRG1/SLC9A7/HLA-E/VPS51/ULK1/KCNK1/STX12/ACAP1/UNC13D/RAB11FIP3/SYT11/VAMP3/VPS52/RABGEF1/PLEKHB2/VTI1B/EEA1/RAB11FIP5/RAB11FIP4/LZTR1/TUBG1/LDLRAP1/SORCS2/ARF6/ZDHHC2/ATP11C/EHD3/DENND6A/EHD4/RAB12/SLC9A6	55
CC	GO:0005791	rough endoplasmic reticulum	29/4919	85/19717	0.03658	0.1715	0.1392	TP63/CYBB/DERL1/SPPL3/RANGRF/HCRT/RPL4/RPS23/SEC61A2/RPL6/KCNJ2/NUCB1/LRPAP1/TRAM2/VTN/SEC61B/NAT8L/ZC3H12A/CKAP4/SYNE3/BGLAP/RPS28/SUCO/CANX/STAU1/CA4/PLOD3/NCF1/CDKAL1	29
CC	GO:0033162	melanosome membrane	7/4919	14/19717	0.03781	0.1741	0.1413	GPNMB/RAB32/DTNBP1/RAB27A/OCA2/RAB38/TYRP1	7
CC	GO:0045009	chitosome	7/4919	14/19717	0.03781	0.1741	0.1413	GPNMB/RAB32/DTNBP1/RAB27A/OCA2/RAB38/TYRP1	7
CC	GO:0090741	pigment granule membrane	7/4919	14/19717	0.03781	0.1741	0.1413	GPNMB/RAB32/DTNBP1/RAB27A/OCA2/RAB38/TYRP1	7
CC	GO:0098685	Schaffer collateral - CA1 synapse	28/4919	82/19717	0.03904	0.178	0.1445	CDK5/SYN1/ACTG1/STAT3/PLAT/CAMK2A/PFN2/SH3GL1/APBA2/STXBP5/PRKCI/CACNG3/DVL1/DTNBP1/WNT7A/RNF216/SYT11/INA/GHRL/LRFN2/PTPRS/SYN2/LRRC4C/BCR/FBXL20/NEFL/FYN/ACTB	28
CC	GO:0016459	myosin complex	23/4919	65/19717	0.03913	0.178	0.1445	MYO7A/MYO1E/MYH10/MYO5C/MYO5A/ACTG2/MYL12B/MYL6/BMF/MYL1/LIMCH1/MYBPC3/MYH7B/MYH7/MYH4/MYO9B/MYL6B/MYH9/MYOM1/MYO18B/MYO3B/MYH6/MYBPC2	23
CC	GO:0031307	integral component of mitochondrial outer membrane	9/4919	20/19717	0.04034	0.1825	0.1481	GDAP1/SYNJ2BP/PINK1/BAK1/CPT1A/RHOT2/FUNDC2/MGARP/FUNDC1	9
CC	GO:0005741	mitochondrial outer membrane	55/4919	178/19717	0.04181	0.188	0.1526	GK/BNIP3L/HK1/MCL1/CYB5B/HK2/BAX/PMAIP1/MTOR/GDAP1/QTRT1/CNP/RSAD2/TSPO/MOAP1/RAB32/BMF/UBB/MSTO1/ACSL1/AMBRA1/RPS27A/SYNJ2BP/BID/PINK1/UBA52/LETMD1/ULK1/TOMM6/BCL2A1/BAK1/ARG1/CNR1/VDAC1/CYP27B1/MTX3/BCL2L1/ACSL4/CPT1A/RAB11FIP5/RHOT2/BPHL/ACACB/FUNDC2/PPP1R15A/TOMM22/AGK/GPAT2/PGAM5/HADHB/LPIN1/BAD/MGARP/FUNDC1/SLC44A1	55
CC	GO:0005776	autophagosome	31/4919	93/19717	0.04284	0.1914	0.1554	SQSTM1/TP53INP2/DAPK2/TEX264/TM9SF1/MAP1LC3A/NBR1/ATG9A/ATP13A2/SNAP29/HTT/FYCO1/AMBRA1/CALCOCO2/ULK1/TP53INP1/FTL/NCOA4/FTH1/UVRAG/ENTPD4/UBQLN2/RAB23/LAMP1/PIK3C3/OSBPL7/PIP4K2A/PIK3R4/TMEM150B/PIP4K2B/RAB12	31
CC	GO:0030133	transport vesicle	113/4919	392/19717	0.04306	0.1914	0.1554	ZNRF1/FURIN/MAP6/HCK/SEC13/SPRED2/ATP6V0D1/SURF4/CEACAM1/CLTB/SEC24D/SEMA4C/SYN1/SYNGR3/MCFD2/SLC2A8/HLA-DQB2/AFTPH/PLIN3/ASTL/STX11/STX5/HLA-H/HCRT/BLOC1S6/SEC16A/ATG9A/HLA-G/SYT4/PAM/KDELR2/SNAP47/ATP13A2/PDE4B/CNIH2/CD74/PPT1/RAB3D/STON2/SLC2A4/NRGN/APBA2/TPRG1L/STXBP5/PRG2/M6PR/SYNGR2/STX1B/AQP2/SGTA/OVGP1/TMED3/PICK1/HLA-DPA1/HLA-E/HLA-DRA/ROGDI/AP1S1/COPE/STX19/TMED9/DTNBP1/TMEM30A/SYTL1/STX12/RAB27A/NRSN2/CHP1/VDAC1/UNC13D/TMED10/YIPF2/SYT11/VAMP3/STX16/BCL2L1/HLA-DQA2/SNAPIN/MCTP2/LAMP1/VTI1B/SYNGR1/DNM1/RAB11FIP5/PTPRS/STX2/SYTL3/RPH3A/GOPC/TRAPPC4/HLA-DPB1/RAB15/SYN2/RAB1A/CA4/DMXL2/NTF3/KIAA1107/SLC9B2/AP1AR/COPG2/SYT15/CNST/SSPN/SV2A/PEF1/HLA-DRB1/SLC40A1/SREBF2/RAB1B/TRIM9/DLG4/USO1	113
CC	GO:0030670	phagocytic vesicle membrane	26/4919	76/19717	0.04452	0.1968	0.1597	RAB31/RAB11FIP1/ATP6V0D1/CYBB/ATP6V0B/HLA-H/HLA-G/RAB32/ATP6V0C/CORO1A/HLA-E/TLR2/HVCN1/SNAP23/TAP1/TLR6/RAPGEF1/RAC2/VAMP3/RAB38/CYBA/RAB23/LAMP1/PIK3C3/PIK3R4/RAB34	26
CC	GO:0005770	late endosome	76/4919	256/19717	0.04731	0.2079	0.1687	NDFIP2/CD1E/SQSTM1/CD68/NTRK1/CTSH/GRN/RASGEF1B/PARM1/CHMP2B/DERL1/AP5S1/MAP1LC3A/CTNS/UBXN6/ANXA2/LDLR/HLA-DMA/STEAP3/NBR1/CCZ1/SNF8/SORL1/MYO5A/SRC/ATG9A/MON1B/ATP13A2/BST2/VPS33B/CD74/HTT/SLC2A4/FYCO1/PIKFYVE/MICALL1/M6PR/TMEM106B/HLA-DRA/LITAF/IFITM3/SLA2/DDIT3/HGS/NAPSA/RAB27A/SLC38A9/UNC13D/YIPF2/KIAA1324/HLA-DMB/SLC29A3/UVRAG/ABCA5/RAPGEF2/LAMP1/PIK3C3/CHID1/VTI1B/CHMP1A/F2R/LAMTOR4/CHMP2A/LAMTOR2/PIK3R4/LAPTM4A/VPS39/AP1AR/MITD1/WDR48/RNF215/MAPK1/HLA-DRB1/CHMP3/OSBPL9/SLC9A6	76
CC	GO:0002102	podosome	12/4919	30/19717	0.0498	0.2176	0.1766	FSCN1/GSN/CTTN/SVIL/SRC/ARHGEF5/ARHGEF2/SH3GL1/FERMT3/SH3PXD2B/WDR1/RHOU	12
CC	GO:0005689	U12-type spliceosomal complex	11/4919	27/19717	0.05195	0.2178	0.1768	RNPC3/SNRNP48/SF3B4/SF3B2/SNRNP25/SNRPB/SNRPD2/YBX1/RBM41/PHF5A/SNRNP35	11
CC	GO:0097431	mitotic spindle pole	11/4919	27/19717	0.05195	0.2178	0.1768	GPSM2/ASPM/FAM83D/AURKA/KIF20B/SPAG5/SMC3/NUMA1/RAE1/KATNBL1/SMC1A	11
CC	GO:0017053	transcriptional repressor complex	28/4919	84/19717	0.05226	0.2178	0.1768	RELB/RBBP8/RCOR1/HMGB1/SKI/CBX5/RBPJ/PRDM16/SP1/JUN/RCOR3/DDX20/RLIM/SIRT2/PASD1/ZNF224/BAZ2A/AKIRIN2/RRP8/MTA1/CTBP1/ARID4A/MTA3/DEPDC1/CCND1/ZFPM1/NCOR1/SIRT1	28
CC	GO:0005845	mRNA cap binding complex	6/4919	12/19717	0.05385	0.2178	0.1768	CYFIP1/ZFP36/FMR1/EIF4E2/EIF4E3/NCBP2	6
CC	GO:0008540	proteasome regulatory particle, base subcomplex	6/4919	12/19717	0.05385	0.2178	0.1768	PSMD1/PSMD2/PSMD9/PSMD5/PSMD10/PSMC5	6
CC	GO:0017119	Golgi transport complex	6/4919	12/19717	0.05385	0.2178	0.1768	COG8/COG7/COG1/TMEM115/COG3/CDC42	6
CC	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	6/4919	12/19717	0.05385	0.2178	0.1768	DTL/DET1/ERCC8/CUL4A/GLMN/CRBN	6
CC	GO:0042555	MCM complex	6/4919	12/19717	0.05385	0.2178	0.1768	MCM4/MCM5/MCM2/TONSL/MCM7/MCM3	6
CC	GO:0044615	nuclear pore nuclear basket	6/4919	12/19717	0.05385	0.2178	0.1768	NUP98/ENY2/NUP153/CETN2/CETN3/NUP35	6
CC	GO:0071564	npBAF complex	6/4919	12/19717	0.05385	0.2178	0.1768	PHF10/SMARCB1/ACTL6A/SMARCA4/SS18/ARID1A	6
CC	GO:0022624	proteasome accessory complex	10/4919	24/19717	0.05387	0.2178	0.1768	PSMD8/PSMD1/PSMD2/PSMD9/PSMD5/PSME2/PSMD10/PSMD7/PSMC5/PSMD11	10
CC	GO:0005680	anaphase-promoting complex	9/4919	21/19717	0.05539	0.2178	0.1768	UBE2C/BUB1B/CDC20/UBE2S/ANAPC11/ANAPC1/MAD2L2/ANAPC13/CDC16	9
CC	GO:0005838	proteasome regulatory particle	9/4919	21/19717	0.05539	0.2178	0.1768	PSMD8/PSMD1/PSMD2/PSMD9/PSMD5/PSMD10/PSMD7/PSMC5/PSMD11	9
CC	GO:0031306	intrinsic component of mitochondrial outer membrane	9/4919	21/19717	0.05539	0.2178	0.1768	GDAP1/SYNJ2BP/PINK1/BAK1/CPT1A/RHOT2/FUNDC2/MGARP/FUNDC1	9
CC	GO:0005777	peroxisome	42/4919	134/19717	0.05552	0.2178	0.1768	MPV17/ABCD1/PMVK/MYO5A/ABCD2/FAR2/VWA8/SLC27A2/CD33/HMGCL/EPHX2/PRDX5/ACSL1/ACOX2/TYSND1/ACOT8/GRHPR/ZADH2/AMACR/GBF1/PEX2/PXMP4/PXMP2/NUDT17/ATAD1/VIM/ACSL4/PEX3/PIK3C3/PEX5/LACC1/PEX11A/ACAD11/GSTK1/NUDT19/PECR/IDI2/PEX13/HSDL2/ACOT6/PEX1/DECR2	42
CC	GO:0042579	microbody	42/4919	134/19717	0.05552	0.2178	0.1768	MPV17/ABCD1/PMVK/MYO5A/ABCD2/FAR2/VWA8/SLC27A2/CD33/HMGCL/EPHX2/PRDX5/ACSL1/ACOX2/TYSND1/ACOT8/GRHPR/ZADH2/AMACR/GBF1/PEX2/PXMP4/PXMP2/NUDT17/ATAD1/VIM/ACSL4/PEX3/PIK3C3/PEX5/LACC1/PEX11A/ACAD11/GSTK1/NUDT19/PECR/IDI2/PEX13/HSDL2/ACOT6/PEX1/DECR2	42
CC	GO:0005811	lipid droplet	27/4919	81/19717	0.05588	0.2178	0.1768	G0S2/HSD3B7/GAPDH/ANXA2/PLIN3/RSAD2/LMLN/VCP/LPCAT2/PITPNM1/STARD13/SYNGR2/BCAP31/IRAK1/GBF1/ATG2B/PLIN2/ACSL4/PRPF19/CKAP4/GIMAP2/CIDEB/DGAT2/AQP7/TRAF6/RDH10/DHRS3	27
CC	GO:0001673	male germ cell nucleus	7/4919	15/19717	0.05598	0.2178	0.1768	HSPA2/TRIP13/TOPBP1/ACTRT3/REC8/TCFL5/MLH3	7
CC	GO:0005662	DNA replication factor A complex	7/4919	15/19717	0.05598	0.2178	0.1768	TONSL/ERCC5/PRPF19/CDC5L/PURB/HELB/XPA	7
CC	GO:0005779	integral component of peroxisomal membrane	7/4919	15/19717	0.05598	0.2178	0.1768	ABCD1/FAR2/SLC27A2/PEX2/PEX3/PEX11A/PEX13	7
CC	GO:0031231	intrinsic component of peroxisomal membrane	7/4919	15/19717	0.05598	0.2178	0.1768	ABCD1/FAR2/SLC27A2/PEX2/PEX3/PEX11A/PEX13	7
CC	GO:0031970	organelle envelope lumen	29/4919	88/19717	0.05607	0.2178	0.1768	TXNIP/SUOX/PRELID1/CPOX/COX17/TUBB/SORL1/DTYMK/TIMM10/BLOC1S1/MICU1/NME4/PINK1/ALOX5/NDUFS1/PARK7/COX6B2/HSD3B2/FBXL4/ARL2BP/PPOX/COA4/AGK/ARL2/CHCHD4/AK2/CEP89/CMC4/TIMM9	29
CC	GO:0030135	coated vesicle	84/4919	289/19717	0.06096	0.2356	0.1912	HBEGF/FURIN/FCGR1B/SEC13/TFRC/YIPF5/MYO1E/HIP1/CD9/CLTB/SEC24D/SNX9/MCFD2/SLC2A8/HLA-DQB2/AFTPH/LDLR/F5/CTLA4/FCGR1A/STX5/HLA-H/SEC16A/CD207/HLA-G/IDUA/KDELR2/VPS33B/CNIH2/CD74/GGA2/STON2/HIP1R/SLC2A4/NRGN/M6PR/TMED3/HLA-DPA1/RGS19/BCAP31/HLA-E/HLA-DRA/DVL1/AP1S1/COPE/TMED9/AP2S1/LRP1/AAK1/RAB27A/UNC13D/SH3BP4/ABCB4/TMED10/VAMP3/CTSZ/TMED5/IL7R/LMAN2/HLA-DQA2/TMED4/YIF1A/YIF1B/VTI1B/ACTR1A/CLVS1/LDLRAP1/GOPC/PACSIN1/HLA-DPB1/LMBRD1/CLINT1/FZD5/KIAA1107/AP3B2/TMED1/COPG2/TYRP1/TMED6/CCDC115/PEF1/HLA-DRB1/SREBF2/USO1	84
CC	GO:0035770	ribonucleoprotein granule	66/4919	223/19717	0.06424	0.247	0.2005	SQSTM1/LARP4/RAC1/CTSH/DYRK3/APOBEC3H/ZFP36/ZC3H12D/POLDIP3/TUBB/TDRD9/BTBD1/LIMD1/PABPC1L/RPS6/VCP/HNRNPA3/TNRC6B/RPL6/DCPS/PITPNM1/CIRBP/UPF1/DIS3L2/FASTKD2/CNOT3/NCL/PAN3/AICDA/GABPB1/SUMO1/EDC4/RBM23/FMR1/INA/RPS4X/ARNTL/ZC3H12A/ELAVL1/CNOT7/CKAP4/OGFOD1/SAMD4B/GIGYF2/UHMK1/TDRD5/YBX1/ZFP36L1/CPEB1/ASZ1/NUFIP2/STAU1/HNRNPL/PNRC2/DDX19A/RBPMS/SMN1/ZFAND1/NSUN2/CDC42/KHSRP/BARD1/PIWIL4/LSM2/ACTB/TRIM5	66
CC	GO:0031968	organelle outer membrane	60/4919	201/19717	0.06468	0.2475	0.2009	GK/BNIP3L/HK1/MCL1/CYB5B/HK2/BAX/PMAIP1/MTOR/GDAP1/QTRT1/CNP/RSAD2/TSPO/MOAP1/RAB32/BMF/UBB/MSTO1/ACSL1/AMBRA1/RPS27A/SYNJ2BP/BID/PINK1/UBA52/LETMD1/ULK1/TOMM6/BCL2A1/BAK1/ARG1/CNR1/VDAC1/EMD/CYP27B1/MTX3/BCL2L1/ACSL4/SYNE3/NUCB2/CPT1A/LRPPRC/RAB11FIP5/RHOT2/BPHL/ACACB/FUNDC2/PPP1R15A/TOMM22/AGK/GPAT2/PGAM5/HADHB/SYNE2/LPIN1/BAD/MGARP/FUNDC1/SLC44A1	60
CC	GO:0005637	nuclear inner membrane	20/4919	58/19717	0.06662	0.2536	0.2059	LMNB1/LMNB2/TMEM43/P2RX1/P2RX6/FAM169A/SUN2/TMEM120B/TMEM120A/LEMD3/SPAG4/EMD/SMAD1/LRPPRC/ERN1/P2RX5/UNC50/TMEM201/P2RX7/SIRT1	20
CC	GO:0009898	cytoplasmic side of plasma membrane	47/4919	154/19717	0.06767	0.2563	0.2081	GNG4/GEM/GNA15/FES/HCK/PTPN7/RACGAP1/HIP1/GNG10/SNX9/SYAP1/AKAP5/GM2A/BLK/ANK1/SRC/TIAM1/GNAS/GNG7/C2CD2L/PTPN4/PTK6/PTPRC/EZR/CYLD/S100A6/RASA3/STAC3/PKP4/LITAF/STAC/GNAI2/NTSR1/RGS1/TRAF2/FER/LDLRAP1/EPB41/CYTH1/GNAQ/ACP1/TRAF6/D2HGDH/GRAMD1A/GNAT3/FYN/DLG4	47
CC	GO:0005758	mitochondrial intermembrane space	26/4919	79/19717	0.06866	0.2588	0.2101	TXNIP/SUOX/PRELID1/CPOX/COX17/DTYMK/TIMM10/BLOC1S1/MICU1/NME4/PINK1/NDUFS1/PARK7/COX6B2/HSD3B2/FBXL4/ARL2BP/PPOX/COA4/AGK/ARL2/CHCHD4/AK2/CEP89/CMC4/TIMM9	26
CC	GO:0012507	ER to Golgi transport vesicle membrane	21/4919	62/19717	0.07274	0.2715	0.2204	SEC13/SEC24D/MCFD2/HLA-DQB2/STX5/HLA-H/SEC16A/HLA-G/CNIH2/CD74/HLA-DPA1/HLA-E/HLA-DRA/TMED10/HLA-DQA2/VTI1B/HLA-DPB1/PEF1/HLA-DRB1/SREBF2/USO1	21
CC	GO:0035580	specific granule lumen	21/4919	62/19717	0.07274	0.2715	0.2204	QPCT/PTPN6/LRG1/CYFIP1/CANT1/HPSE/TIMP2/NEU1/GGH/LYZ/TCN1/TOLLIP/QSOX1/SPTAN1/CTSD/ARG1/RAB27A/CTSZ/CNN2/DEFA4/NIT2	21
CC	GO:0005743	mitochondrial inner membrane	132/4919	473/19717	0.07454	0.2769	0.2248	PPIF/SLC25A45/SFXN1/SCO2/C15orf48/MRPL37/MRPL28/LGALS3/MPV17/SLC25A44/TYMS/COX8A/DHODH/SLC25A1/CPOX/FDXR/MRPL51/TIMM17A/MRPS36/SLC25A23/MTCH2/DNAJC30/MRPL22/CNP/STAT3/RSAD2/SRC/IFI6/MRPL18/MRPS5/TIMM10/MRPS18C/CLU/MRPS11/NDUFB11/MICU1/COX6A1/UQCRC1/SLC25A25/RPS3/NOA1/TMEM11/NDUFB8/COX18/GCAT/PARL/NME4/MRPS6/PINK1/TIMM22/HIGD2A/SLC25A14/TIMM50/ROMO1/SLC25A28/LETMD1/COA3/MRPL20/NDUFS1/CHCHD6/GRPEL1/MRPL50/SLC25A43/MRPL36/MRPS2/NDUFS7/MRPL35/MRPL27/MRPL15/ATAD3A/SLC25A5/COX6B2/MRPS25/NDUFB10/SCO1/MRPL34/BCL2L1/NDUFC1/MRPS14/MRPL13/IMMP1L/MTG1/PTPMT1/SLC25A36/NDUFA9/PTCD3/COX4I1/DUSP18/ECSIT/UQCR11/HSD3B2/SLC25A48/MRPL10/NDUFA12/PPOX/COQ10A/TAMM41/MRPL54/NNT/SLC25A42/DAP3/PAM16/ACAD11/SPHK2/TTC19/MRPL2/SLC25A4/AGK/MRPL39/CYP11A1/SLC9B2/TAZ/NDUFA4/NDUFB2/MPC1/NDUFAF5/SLC25A40/GUF1/NDUFA13/COX11/HADHB/SLC25A52/OMA1/ABCB8/SPG7/NDUFAF2/MRPL43/SLC25A16/TIMM9/MRPL48/CRLS1/PGS1	132
CC	GO:0019867	outer membrane	60/4919	203/19717	0.07622	0.2818	0.2287	GK/BNIP3L/HK1/MCL1/CYB5B/HK2/BAX/PMAIP1/MTOR/GDAP1/QTRT1/CNP/RSAD2/TSPO/MOAP1/RAB32/BMF/UBB/MSTO1/ACSL1/AMBRA1/RPS27A/SYNJ2BP/BID/PINK1/UBA52/LETMD1/ULK1/TOMM6/BCL2A1/BAK1/ARG1/CNR1/VDAC1/EMD/CYP27B1/MTX3/BCL2L1/ACSL4/SYNE3/NUCB2/CPT1A/LRPPRC/RAB11FIP5/RHOT2/BPHL/ACACB/FUNDC2/PPP1R15A/TOMM22/AGK/GPAT2/PGAM5/HADHB/SYNE2/LPIN1/BAD/MGARP/FUNDC1/SLC44A1	60
CC	GO:0016461	unconventional myosin complex	5/4919	10/19717	0.07747	0.2829	0.2296	MYO7A/MYO5A/MYL6/MYL6B/MYO18B	5
CC	GO:0033643	host cell part	7/4919	16/19717	0.07871	0.2829	0.2296	GBP2/AXL/PI4K2A/FMR1/SCO1/CNOT7/GBP4	7
CC	GO:0071437	invadopodium	7/4919	16/19717	0.07871	0.2829	0.2296	FSCN1/ITGA3/PLAUR/SVIL/PAK1/EZR/RUFY3	7
CC	GO:0005875	microtubule associated complex	46/4919	152/19717	0.07895	0.2829	0.2296	KIF20A/AURKB/KIF2C/CDCA8/KIF14/KIFC1/KIF4A/KIF15/BIRC5/AURKA/KIF23/KIF24/KIF20B/TTBK1/KIF1C/KIF18A/YWHAE/LRP8/KIF11/PEA15/KLC1/WDR34/CENPE/DYNLRB1/KIF4B/KLC3/CCDC114/DNHD1/MID1/KIF3C/MAP1S/TOPORS/WDR60/TRIM54/KLC4/HAUS5/DNAI2/ACTR1A/MAP1A/STAU1/FNTB/KIF26B/TCTE3/KIF19/KIFC2/DNAH6	46
CC	GO:0005681	spliceosomal complex	55/4919	185/19717	0.07897	0.2829	0.2296	U2AF1/PRPF40B/LGALS3/RBM22/CWC25/LUC7L3/SMU1/PPIH/EFTUD2/HNRNPA3/SNRPC/CCDC12/SNRNP40/CIRBP/UPF1/RNPC3/MAGOHB/MFAP1/TFIP11/SART1/PRPF31/SNRNP48/AKAP17A/SF3B4/SF3B2/RBM17/U2AF1L4/WBP4/DHX35/SNRNP25/DHX38/CWF19L2/ZNF830/SNRPB/PRPF19/C9orf78/PPP1R8/MAGOH/RBMY1B/PRPF3/CDC5L/DDX41/PNN/HTATSF1/SNRPD2/YBX1/CDC40/RBM3/CWC22/RBM41/PHF5A/SYF2/SNRNP35/PRPF38B/LSM2	55
CC	GO:0001931	uropod	6/4919	13/19717	0.07945	0.2829	0.2296	SCIMP/EZR/PIP5K1B/FLOT1/ICAM2/MYH9	6
CC	GO:0005675	transcription factor TFIIH holo complex	6/4919	13/19717	0.07945	0.2829	0.2296	CDK7/ERCC2/GTF2H2/GTF2H1/MNAT1/GTF2H5	6
CC	GO:0031254	cell trailing edge	6/4919	13/19717	0.07945	0.2829	0.2296	SCIMP/EZR/PIP5K1B/FLOT1/ICAM2/MYH9	6
CC	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	29/4919	91/19717	0.0821	0.2909	0.2362	GNG4/GNA15/FES/HCK/RACGAP1/HIP1/GNG10/SNX9/SYAP1/BLK/SRC/TIAM1/GNAS/GNG7/PTK6/CYLD/S100A6/STAC3/STAC/GNAI2/RGS1/FER/CYTH1/GNAQ/D2HGDH/GRAMD1A/GNAT3/FYN/DLG4	29
CC	GO:0015030	Cajal body	25/4919	77/19717	0.08399	0.2963	0.2405	U2AF1/SCARNA17/EFTUD2/CDK2/SCARNA10/SNRPC/TRIM22/NOP10/ISG20/SART1/PRPF31/NOLC1/FMR1/DDX42/OIP5/SCARNA13/NPAT/FBL/WRAP53/PRPF3/EAF1/ELL/LSG1/SMN1/SCARNA15	25
CC	GO:0036464	cytoplasmic ribonucleoprotein granule	62/4919	212/19717	0.08633	0.3031	0.2461	SQSTM1/LARP4/RAC1/CTSH/DYRK3/APOBEC3H/ZFP36/ZC3H12D/POLDIP3/TUBB/TDRD9/BTBD1/LIMD1/PABPC1L/RPS6/VCP/TNRC6B/RPL6/DCPS/PITPNM1/CIRBP/UPF1/DIS3L2/CNOT3/NCL/PAN3/AICDA/GABPB1/EDC4/RBM23/FMR1/INA/RPS4X/ARNTL/ZC3H12A/ELAVL1/CNOT7/CKAP4/OGFOD1/SAMD4B/GIGYF2/UHMK1/TDRD5/YBX1/ZFP36L1/CPEB1/ASZ1/NUFIP2/STAU1/PNRC2/DDX19A/RBPMS/SMN1/ZFAND1/NSUN2/CDC42/KHSRP/BARD1/PIWIL4/LSM2/ACTB/TRIM5	62
CC	GO:0009897	external side of plasma membrane	110/4919	393/19717	0.08985	0.3141	0.2549	EBI3/MCAM/CD86/ANPEP/CD1E/CD276/ITGA2/ICAM1/ITGA3/IL1R1/ABCG1/CD83/CD80/CXCR6/PDCD1/TLR8/IL17A/CSF3R/TFRC/CCR1/CCRL2/ENOX1/CD9/ULBP2/TNF/TNFRSF4/SEMA7A/IL2RA/CD1A/TLR4/BTN2A2/CXCL10/RAET1E/LDLR/IL2RB/ERMAP/CD1C/CTLA4/CCR6/FCN1/CCR2/HLA-H/CCR4/P2RX1/LY6G5C/HLA-G/IL2RG/CD1B/IL12RB2/CD33/CD74/CD1D/AMOT/CCR5/SLC2A4/S1PR1/CEACAM5/SDC1/MAP3K5/CD79B/PTPRC/TNFRSF9/ITGA1/HLA-E/ANXA5/ITGA6/CXCL9/ABCA1/FLOT1/FCGRT/CSF2RA/ANTXR2/MICA/IL12RB1/IL27RA/THY1/CD19/LAG3/ITGAE/MR1/CUBN/IL5RA/IL7R/CCR8/IL11RA/PDCD1LG2/SCUBE1/CD3E/IL13/DNAI2/LAMP1/F3/BTN3A2/CD34/PRNP/ULBP1/CD6/ITGA2B/INSR/FGF8/CA4/CD248/RTN4R/HHLA2/ADAM9/CDH5/KLRK1/CXCR5/P2RX7/CX3CR1	110
CC	GO:0030173	integral component of Golgi membrane	20/4919	60/19717	0.09057	0.3151	0.2558	FURIN/SLC35A2/SGMS1/GALNT2/SGMS2/SLC35B1/SYT4/CSGALNACT1/FKTN/QSOX1/TBC1D20/SLC35B2/ACER2/ENTPD4/YIF1A/YIF1B/PCSK4/UNC50/PCSK5/SLC35B4	20
CC	GO:0033267	axon part	107/4919	382/19717	0.09172	0.3177	0.2579	TIAM2/TPX2/FSCN1/KIF4A/ITGA2/ADORA2A/AURKA/ITGA3/NTRK2/MICAL1/KIF20B/CYFIP1/ATP6V0D1/KIF1C/ORAI2/CDK5/TIMP2/YWHAE/PTCH1/SYAP1/MYH10/ANK1/CTTN/NCS1/USP9X/ZFYVE27/KLC1/ACTG1/CYTH2/TMOD2/MYO5A/BLOC1S6/SCN1B/TIAM1/BLOC1S1/AMIGO1/SRI/KCNA3/BLOC1S4/RNF40/STMN3/TPRG1L/CCK/PREX1/CASR/PINK1/SPTBN1/FGF13/ARHGAP4/TWF2/L1CAM/TUBB3/DVL1/AP3D1/AP1S1/ARPC5/LRP1/AAK1/DTNBP1/NDRG2/THY1/SLC4A10/TANC1/CNR1/NTSR1/ELK1/BASP1/FMR1/TUBB4A/KCNQ3/SYT11/CTSZ/AP3M2/GDPD5/ERC2/BRSK2/SNAPIN/SIRT2/DNM1/EEA1/TNFRSF1B/KCNC4/UTRN/DICER1/PRKCB/PACSIN1/MAP1A/OTX2/ANKRD9/NEFL/NPFF/AP3B2/RUFY3/RTN4R/UCHL1/TRPC5/SPG7/KCNK2/SYBU/DLG4/MGARP/ILK/RAC3/PCDH9/SLC9A6/TERF2/ACTB	107
CC	GO:0009295	nucleoid	15/4919	43/19717	0.09453	0.3245	0.2634	MPG/HSPA9/LRRC59/FASTKD2/VDAC1/ATAD3A/SLC25A5/DNA2/LRPPRC/POLG2/SSBP1/TRMT10C/TFB2M/HADHB/TUFM	15
CC	GO:0042645	mitochondrial nucleoid	15/4919	43/19717	0.09453	0.3245	0.2634	MPG/HSPA9/LRRC59/FASTKD2/VDAC1/ATAD3A/SLC25A5/DNA2/LRPPRC/POLG2/SSBP1/TRMT10C/TFB2M/HADHB/TUFM	15
CC	GO:0046930	pore complex	9/4919	23/19717	0.09516	0.3249	0.2637	PPIF/BAX/PLEKHA7/BAK1/VDAC1/CD34/C6/SPG7/PDZD11	9
CC	GO:0043025	neuronal cell body	137/4919	497/19717	0.09549	0.3249	0.2637	NCDN/TPX2/ADORA2A/AURKA/CIT/PTPRF/NTRK1/TTBK1/CYFIP1/ZNF385A/PVALB/TMPRSS3/CDK5/TIMP2/ASCL1/SYAP1/MYH10/DHODH/LRP8/CD200/CYBB/CHRNA10/MTOR/HOMER2/SLC2A3/CCR2/MYO5A/SCN1B/CCR4/NUMA1/TIAM1/SLC1A4/ARHGEF2/SYT4/PAM/SNAP47/HTR2A/RRM1/ATP13A2/AMIGO1/KCNE3/TMEM50A/UBB/TGFB3/PPT1/P2RX6/KCNJ2/CPNE5/MYOT/RIC3/CRTC1/HIP1R/NRGN/UBXN1/NQO1/CCK/MAGOHB/CASR/FBXO31/SMURF1/LRP4/CNNM4/TRPM4/ITGA1/AIF1/L1CAM/ERCC8/KCNN4/DVL1/ROGDI/SEZ6L/PI4K2A/KCNK1/LRP1/THY1/ARG1/SLC4A10/TANC1/NTSR1/NRSN2/NDUFS7/ELK1/SLC38A2/PPP5C/FMR1/TUBB4A/MAP1S/CKB/MCRS1/NDN/GRIN3B/CYBA/EEF1A2/MAP2K4/SIAH2/GDPD5/GSK3A/ACSL4/RAPGEF2/BGLAP/LAMP1/SIRT2/VTI1B/GIGYF2/TNFRSF1B/KCNC4/PTPRS/KCND3/CANX/POLR2M/CHRNA3/LRP6/MAP1A/INSR/STAU1/EFHC1/FZD5/NCF1/SMN1/NPFF/RUFY3/TGFB1/CDC42/STRN3/RTN4R/SV2A/UCHL1/ADNP/MAPK1/TRPC5/KCND1/KCNK2/GDI1/P2RX7/CX3CR1/ILK/RAC3	137
CC	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane	23/4919	71/19717	0.09652	0.327	0.2654	SURF4/GORASP1/MCFD2/SPPL3/F5/STX5/CNIH2/WHAMMP3/TMED3/BCAP31/TBC1D20/TMED9/TAP1/TMED10/PIEZO1/PRRG4/CTSZ/TMED5/LMAN2/RAB2A/WHAMM/TMED1/RAB1B	23
CC	GO:0000784	nuclear chromosome, telomeric region	38/4919	125/19717	0.09697	0.3271	0.2655	CDK1/MCM4/MCM5/PML/SIRT6/PPP1CB/BRCA2/FEN1/RAD51/MCM2/CBX5/TP53BP1/PIF1/ORC1/XRCC6/SUN2/UPF1/MCM7/TERF1/TFIP11/TNKS2/TOX4/ACD/CTC1/THOC3/MCM3/POT1/XRCC3/XRCC1/DNA2/ATR/WDR82/TINF2/SIRT7/ATM/ORC2/ERCC1/TERF2	38
CC	GO:0055029	nuclear DNA-directed RNA polymerase complex	33/4919	107/19717	0.09857	0.3309	0.2686	KAT2A/POLR2J3/POLR3H/CDK7/TAF1L/SUPT3H/POLR1D/TAF9B/RECQL5/TAF6L/TAF10/POLR2I/MCM3/ERCC2/PEX2/RPRD1A/TAF11/GTF2H2/POLR2C/GTF2H1/ZNRD1/ZNF768/TAF7/TAF6/POLR2M/MNAT1/POLR2J/CRCP/GTF2H5/POLR3GL/POLR2A/POLR1B/ERCC1	33
CC	GO:0005721	pericentric heterochromatin	8/4919	20/19717	0.1007	0.3309	0.2686	CENPA/ESCO2/INCENP/CBX5/SNAI1/HELLS/KDM4C/LRWD1	8
CC	GO:0005839	proteasome core complex	8/4919	20/19717	0.1007	0.3309	0.2686	PSMF1/PSMA5/PSMB7/PSMB5/PSMB4/PSMA3/PSMB1/PSMB3	8
CC	GO:0035145	exon-exon junction complex	8/4919	20/19717	0.1007	0.3309	0.2686	RNPS1/UPF1/MAGOHB/UPF3A/MAGOH/R3HCC1/PNN/SMG6	8
CC	GO:0035371	microtubule plus-end	8/4919	20/19717	0.1007	0.3309	0.2686	KIF2C/SPAG5/MYO5A/MAPRE2/NUMA1/SLAIN2/NCKAP5/CKAP5	8
CC	GO:0071782	endoplasmic reticulum tubular network	8/4919	20/19717	0.1007	0.3309	0.2686	ZFYVE27/ASPH/C2CD2L/PARP16/EMD/ARV1/REEP5/REEP1	8
CC	GO:0000795	synaptonemal complex	14/4919	40/19717	0.1016	0.331	0.2687	HSPA2/SMC3/SYN1/SYCE3/INCENP/BRCA2/PLK1/RAD51/UBE2I/REC8/STAG3/SYCE2/MLH3/RNF212	14
CC	GO:0099086	synaptonemal structure	14/4919	40/19717	0.1016	0.331	0.2687	HSPA2/SMC3/SYN1/SYCE3/INCENP/BRCA2/PLK1/RAD51/UBE2I/REC8/STAG3/SYCE2/MLH3/RNF212	14
CC	GO:0000803	sex chromosome	11/4919	30/19717	0.1043	0.3384	0.2747	ESCO2/UBE2A/PBX4/PLK4/UBE2B/CDK2/EED/SUMO1/PCGF5/DMRTC2/SMC5	11
CC	GO:0030175	filopodium	32/4919	104/19717	0.1052	0.3398	0.2758	TIAM2/FSCN1/ACPP/ITGA3/EPHB1/CYFIP1/CDK5/NF2/DEF6/MYO5A/ACTG2/HLA-G/TBC1D10C/FGF13/EZR/VASP/TWF2/ITGA6/TUBB3/FMR1/ARL4C/FZD9/UTRN/ARF6/ACTA2/PPP1R9B/RAPH1/RUFY3/CDC42/SYNE2/SPATA13/NGDN	32
CC	GO:0000790	nuclear chromatin	105/4919	377/19717	0.1056	0.3398	0.2758	CENPA/CDCA5/HMGB3/ASF1B/KLF2/SRF/KLF4/IRF4/C17orf49/ESCO2/SPI1/CHAF1A/UBE2A/ZNF385A/UHRF1/TFPT/TP63/CHAF1B/DPF3/ZNHIT1/HMGB1/SIRT6/E2F1/MSH6/PHF10/UBE2B/NASP/RAD51/SMARCB1/ING3/STAT3/RAD51AP1/ASXL2/TTI1/CBX5/MBD2/DVL3/KAT2A/ACTL6A/RUNX2/SATB1/CBX8/TCF7L2/SMARCA4/MEF2D/TBX6/EED/EZH2/TIMELESS/MUC1/SS18/SP1/ASXL1/HMGXB4/TRPS1/RXRA/ARID1A/JUN/MEF2B/MCRS1/CBX7/CITED2/CEBPB/UCHL5/YY2/BRD9/DFFB/RCC1/XRCC1/EME1/KLHDC3/SFR1/DDX11/GABPA/SIRT2/KAT6B/ESR1/DLX5/FER/YY1AP1/DPF1/CPSF6/MAX/MTA1/STAT1/MBD1/POLR3GL/MTA3/UHRF2/SIRT7/POGZ/NUCKS1/PPARD/KDM4C/PLCB1/POU4F1/RARA/ASF1A/LDB1/GATA3/NCOR1/TIPIN/KAT6A/ACTB/SIRT1	105
CC	GO:0000428	DNA-directed RNA polymerase complex	33/4919	108/19717	0.1092	0.343	0.2784	KAT2A/POLR2J3/POLR3H/CDK7/TAF1L/SUPT3H/POLR1D/TAF9B/RECQL5/TAF6L/TAF10/POLR2I/MCM3/ERCC2/PEX2/RPRD1A/TAF11/GTF2H2/POLR2C/GTF2H1/ZNRD1/ZNF768/TAF7/TAF6/POLR2M/MNAT1/POLR2J/CRCP/GTF2H5/POLR3GL/POLR2A/POLR1B/ERCC1	33
CC	GO:0005798	Golgi-associated vesicle	52/4919	178/19717	0.1098	0.343	0.2784	FURIN/MAP6/SEC13/YIPF5/CLTB/SEC24D/MCFD2/HLA-DQB2/AFTPH/SPPL3/F5/STX5/HLA-H/SEC16A/HLA-G/KDELR2/CNIH2/CD74/SLC2A4/NRGN/STK16/NUCB1/TMED3/HLA-DPA1/HLA-E/HLA-DRA/AP1S1/COPE/TMED9/TMED10/CTSZ/TMED5/LMAN2/HLA-DQA2/TMED4/YIF1A/ITM2B/YIF1B/VTI1B/ACTR1A/GOPC/PACSIN1/HLA-DPB1/TMED1/COPG2/TMED6/CCDC115/PEF1/CHIC2/HLA-DRB1/SREBF2/USO1	52
CC	GO:0005684	U2-type spliceosomal complex	28/4919	90/19717	0.1106	0.343	0.2784	PRPF40B/RBM22/CWC25/LUC7L3/SMU1/EFTUD2/SNRPC/CCDC12/SNRNP40/MAGOHB/MFAP1/TFIP11/SART1/PRPF31/SF3B4/SF3B2/WBP4/SNRPB/PRPF19/PRPF3/CDC5L/HTATSF1/SNRPD2/CDC40/CWC22/PHF5A/SYF2/LSM2	28
CC	GO:0005744	TIM23 mitochondrial import inner membrane translocase complex	6/4919	14/19717	0.1107	0.343	0.2784	TIMM17A/TIMM10/TIMM50/ROMO1/GRPEL1/PAM16	6
CC	GO:0030688	preribosome, small subunit precursor	6/4919	14/19717	0.1107	0.343	0.2784	RRP1/BYSL/FAM207A/RIOK1/NOP14/UTP20	6
CC	GO:0033276	transcription factor TFTC complex	6/4919	14/19717	0.1107	0.343	0.2784	KAT2A/SUPT3H/TAF9B/TAF10/TAF7/TAF6	6
CC	GO:0034518	RNA cap binding complex	6/4919	14/19717	0.1107	0.343	0.2784	CYFIP1/ZFP36/FMR1/EIF4E2/EIF4E3/NCBP2	6
CC	GO:0031228	intrinsic component of Golgi membrane	21/4919	65/19717	0.1112	0.343	0.2784	FURIN/SLC35A2/SGMS1/GALNT2/SGMS2/SLC35B1/SYT4/CSGALNACT1/FKTN/QSOX1/TBC1D20/SLC35B2/ACER2/ENTPD4/YIF1A/YIF1B/PCSK4/ZDHHC9/UNC50/PCSK5/SLC35B4	21
CC	GO:0035861	site of double-strand break	19/4919	58/19717	0.1122	0.343	0.2784	RBBP8/ESCO2/RAD51/TP53BP1/VCP/RFWD3/TIMELESS/ARPC5/RNF8/APLF/SAMHD1/PRPF19/WRAP53/MAD2L2/HELB/SMC5/RNF138/WAS/RNF168	19
CC	GO:0016591	RNA polymerase II, holoenzyme	26/4919	83/19717	0.1131	0.343	0.2784	KAT2A/POLR2J3/CDK7/TAF1L/SUPT3H/TAF9B/RECQL5/TAF6L/TAF10/POLR2I/ERCC2/PEX2/RPRD1A/TAF11/GTF2H2/POLR2C/GTF2H1/ZNF768/TAF7/TAF6/POLR2M/MNAT1/POLR2J/GTF2H5/POLR2A/ERCC1	26
CC	GO:0030880	RNA polymerase complex	34/4919	112/19717	0.1132	0.343	0.2784	ZNFX1/KAT2A/POLR2J3/POLR3H/CDK7/TAF1L/SUPT3H/POLR1D/TAF9B/RECQL5/TAF6L/TAF10/POLR2I/MCM3/ERCC2/PEX2/RPRD1A/TAF11/GTF2H2/POLR2C/GTF2H1/ZNRD1/ZNF768/TAF7/TAF6/POLR2M/MNAT1/POLR2J/CRCP/GTF2H5/POLR3GL/POLR2A/POLR1B/ERCC1	34
CC	GO:0030426	growth cone	50/4919	171/19717	0.1135	0.343	0.2784	TIAM2/FSCN1/ITGA3/KIF20B/CYFIP1/ORAI2/CDK5/TIMP2/YWHAE/PTCH1/SYAP1/MYH10/CTTN/USP9X/ZFYVE27/KLC1/CYTH2/TMOD2/MYO5A/TIAM1/STMN3/PREX1/PINK1/FGF13/ARHGAP4/TWF2/L1CAM/TUBB3/DVL1/ARPC5/LRP1/DTNBP1/NDRG2/THY1/CNR1/BASP1/FMR1/CTSZ/GDPD5/ERC2/SIRT2/UTRN/DICER1/OTX2/NEFL/RUFY3/RTN4R/TRPC5/RAC3/PCDH9	50
CC	GO:0019774	proteasome core complex, beta-subunit complex	5/4919	11/19717	0.1137	0.343	0.2784	PSMB7/PSMB5/PSMB4/PSMB1/PSMB3	5
CC	GO:0031932	TORC2 complex	5/4919	11/19717	0.1137	0.343	0.2784	MTOR/TTI1/MAPKAP1/SESN2/MLST8	5
CC	GO:0045240	dihydrolipoyl dehydrogenase complex	5/4919	11/19717	0.1137	0.343	0.2784	MRPS36/BCKDK/OGDH/KAT2A/DLST	5
CC	GO:0072687	meiotic spindle	5/4919	11/19717	0.1137	0.343	0.2784	ASPM/AURKA/HSPA2/FBXO5/SIRT2	5
CC	GO:0031253	cell projection membrane	96/4919	345/19717	0.119	0.3575	0.2902	RASGRP2/FSCN1/ADORA2A/ITGA3/RAC1/EVC/PLAUR/IQCE/TIRAP/BBS2/CEACAM1/ROM1/CORO1C/KSR1/PTCH1/PDE4A/CLTB/NF2/GPR161/AKAP5/FGD2/ANK1/CYS1/IFIT5/PLEKHA1/DOCK8/SRC/PSD4/TIAM1/ARHGEF2/HLA-G/SCIMP/PDXP/PAK1/SH3YL1/SNAP29/PKD2/ATF4/RPS3/HIP1R/TBC1D10C/GUCA1C/EPS8L2/SPTBN1/MTMR9/EZR/CLASP2/VASP/AIF1/CFL1/PLXND1/DRD1/KCNK1/BBS9/THY1/SLC26A6/SYTL1/EEF1A1/PSD3/CNGA1/EFCAB7/CUBN/EPB41L5/CD44/PIEZO1/PHLPP1/GABRG2/EVC2/ARF4/TAS2R43/KCNC4/TAS2R4/UMOD/SLC27A4/CYBRD1/FZD9/UTRN/TMEM67/TESC/PACSIN1/INSR/PCDHB13/ARF6/TPM1/AIF1L/CA4/APC/PPP1R9B/EHD3/PIP5K1A/PLB1/SYNE2/DHRS3/PDE6B/SPATA13/SHISA7	96
CC	GO:0043601	nuclear replisome	9/4919	24/19717	0.1199	0.3589	0.2913	TONSL/POLD4/ERCC5/MCM3/PRPF19/CDC5L/PURB/HELB/XPA	9
CC	GO:0016363	nuclear matrix	33/4919	109/19717	0.1206	0.3594	0.2918	CENPF/KIF4A/LMNB1/UHRF1/PSPC1/TGFB1I1/SFPQ/PML/SMC3/CENPW/TENM1/NUMA1/KIF4B/MORC2/SATB1/ATXN1/YEATS4/CFL1/ERCC8/ALOX5/MAEA/ZNF326/CEBPB/VIM/ZNF703/CLIC4/PIAS4/CHMP1A/SMC1A/MBD1/TINF2/OGG1/PHF5A	33
CC	GO:0016323	basolateral plasma membrane	62/4919	217/19717	0.1235	0.3664	0.2974	SLC29A2/ITGA3/ABCC1/TFRC/CEACAM1/ST14/GM2A/ANK1/SLC4A2/SLC29A1/ANXA2/LDLR/ARRB1/RHCG/PKD2/CD1D/HEPH/CEACAM5/SLC51A/SYNJ2BP/ATP1B1/CASR/AQP2/EZR/CNNM4/SLC4A11/ITGA6/FLOT1/SCRIB/NOD2/ATP2B4/LRP1/SLC26A6/SLC4A10/CADM1/ABCC6/ERBB2/CD44/TSHR/CA2/SLC22A8/CLCA2/CLDN7/CA11/CD34/SLC16A10/STX2/UMOD/LDLRAP1/EPB41/SLC23A2/P2RY1/SLC12A6/HPGD/SLC9B2/LIN7C/ADAM9/SLCO4C1/PDGFB/CLDN4/SLC40A1/PDZD11	62
CC	GO:0090734	site of DNA damage	23/4919	73/19717	0.1239	0.3664	0.2974	RBBP8/ESCO2/RAD51/CBX5/TP53BP1/VCP/RFWD3/TIMELESS/ARPC5/RNF8/WDR76/APLF/SAMHD1/PRPF19/WRAP53/AUNIP/MAD2L2/HELB/ADPRHL2/SMC5/RNF138/WAS/RNF168	23
CC	GO:0030427	site of polarized growth	51/4919	176/19717	0.1252	0.3689	0.2994	TIAM2/FSCN1/ITGA3/KIF20B/CYFIP1/ORAI2/CDK5/TIMP2/YWHAE/PTCH1/SYAP1/MYH10/CTTN/USP9X/ZFYVE27/KLC1/CYTH2/TMOD2/MYO5A/TIAM1/STMN3/PREX1/PINK1/FGF13/ARHGAP4/TWF2/L1CAM/TUBB3/DVL1/ARPC5/PI4K2A/LRP1/DTNBP1/NDRG2/THY1/CNR1/BASP1/FMR1/CTSZ/GDPD5/ERC2/SIRT2/UTRN/DICER1/OTX2/NEFL/RUFY3/RTN4R/TRPC5/RAC3/PCDH9	51
CC	GO:0032806	carboxy-terminal domain protein kinase complex	8/4919	21/19717	0.1286	0.3774	0.3063	CDK7/CCNT2/ERCC2/CCNK/GTF2H2/GTF2H1/MNAT1/GTF2H5	8
CC	GO:0070461	SAGA-type complex	10/4919	28/19717	0.1368	0.3986	0.3235	ENY2/KAT2A/SUPT3H/TAF9B/TAF6L/TAF10/TAF7/TAF6/TADA2A/TADA1	10
CC	GO:0090543	Flemming body	10/4919	28/19717	0.1368	0.3986	0.3235	KIF14/KIF23/CEP55/RACGAP1/CAPG/RALA/IST1/ARF6/CHAMP1/NUP62	10
CC	GO:0005859	muscle myosin complex	7/4919	18/19717	0.1377	0.3996	0.3243	MYL1/MYBPC3/MYH7/MYH4/MYL6B/MYOM1/MYH6	7
CC	GO:0005720	nuclear heterochromatin	12/4919	35/19717	0.1403	0.4055	0.3291	CENPA/ESCO2/UHRF1/SIRT6/CBX5/SATB1/EED/EME1/SIRT2/UHRF2/SIRT7/SIRT1	12
CC	GO:0000123	histone acetyltransferase complex	26/4919	85/19717	0.1409	0.4058	0.3294	DPF3/PHF10/ING3/ING5/KANSL3/MORF4L2/KANSL1L/ENY2/KAT2A/ACTL6A/YEATS4/SUPT3H/TAF9B/TAF6L/TAF10/MCRS1/BRPF3/TAF7/KAT6B/DPF1/TAF6/TADA2A/TADA1/ZZZ3/KAT6A/ACTB	26
CC	GO:0001725	stress fiber	21/4919	67/19717	0.1427	0.408	0.3312	FSCN1/ABLIM1/SH2B2/ZYX/FHOD1/MYH10/PDLIM4/TRIP6/CORO1B/PDLIM7/LIMCH1/ACTN4/XIRP2/MYH7/CYBA/BAG3/MYH9/CNN2/TPM1/MYH6/ILK	21
CC	GO:0097517	contractile actin filament bundle	21/4919	67/19717	0.1427	0.408	0.3312	FSCN1/ABLIM1/SH2B2/ZYX/FHOD1/MYH10/PDLIM4/TRIP6/CORO1B/PDLIM7/LIMCH1/ACTN4/XIRP2/MYH7/CYBA/BAG3/MYH9/CNN2/TPM1/MYH6/ILK	21
CC	GO:0030658	transport vesicle membrane	59/4919	208/19717	0.1439	0.4097	0.3326	ZNRF1/MAP6/SEC13/SPRED2/CEACAM1/CLTB/SEC24D/SEMA4C/SYN1/SYNGR3/MCFD2/HLA-DQB2/AFTPH/STX5/HLA-H/SEC16A/HLA-G/SYT4/PAM/SNAP47/CNIH2/CD74/NRGN/TPRG1L/SYNGR2/AQP2/SGTA/HLA-DPA1/HLA-E/HLA-DRA/AP1S1/DTNBP1/TMEM30A/STX12/TMED10/SYT11/VAMP3/STX16/BCL2L1/HLA-DQA2/SNAPIN/MCTP2/LAMP1/VTI1B/SYNGR1/RAB11FIP5/PTPRS/RPH3A/HLA-DPB1/SYN2/RAB1A/CA4/DMXL2/SLC9B2/SV2A/PEF1/HLA-DRB1/SREBF2/USO1	59
CC	GO:0005643	nuclear pore	27/4919	89/19717	0.1461	0.413	0.3352	MVP/SEC13/NUP98/RGPD2/ENY2/NUP153/NUP88/SUMO1/KPNA3/PARP11/POM121C/NUP205/RAE1/NUP50/POM121L2/GLE1/CETN2/SNUPN/NUP93/DDX19A/CETN3/NUP35/AAAS/TMEM33/RGPD1/NUP62/SEH1L	27
CC	GO:0005665	RNA polymerase II, core complex	6/4919	15/19717	0.1471	0.413	0.3352	POLR2J3/POLR2I/POLR2C/ZNF768/POLR2J/POLR2A	6
CC	GO:0031616	spindle pole centrosome	6/4919	15/19717	0.1471	0.413	0.3352	AURKB/AURKA/DLGAP5/NUMA1/EMD/NSFL1C	6
CC	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane	6/4919	15/19717	0.1471	0.413	0.3352	DNAJA1/PTPN1/SPPL3/PKD2/EPM2AIP1/RPS28	6
CC	GO:0150034	distal axon	79/4919	285/19717	0.1539	0.4268	0.3464	TIAM2/FSCN1/ITGA2/ITGA3/NTRK2/MICAL1/KIF20B/CYFIP1/ATP6V0D1/ORAI2/CDK5/TIMP2/YWHAE/PTCH1/SYAP1/MYH10/CTTN/NCS1/USP9X/ZFYVE27/KLC1/ACTG1/CYTH2/TMOD2/MYO5A/TIAM1/SRI/KCNA3/RNF40/STMN3/TPRG1L/CCK/PREX1/CASR/PINK1/FGF13/ARHGAP4/TWF2/L1CAM/TUBB3/DVL1/AP3D1/AP1S1/ARPC5/LRP1/AAK1/DTNBP1/NDRG2/THY1/SLC4A10/TANC1/CNR1/NTSR1/ELK1/BASP1/FMR1/SYT11/CTSZ/GDPD5/ERC2/BRSK2/SIRT2/KCNC4/UTRN/DICER1/PRKCB/PACSIN1/OTX2/NEFL/NPFF/RUFY3/RTN4R/TRPC5/KCNK2/ILK/RAC3/PCDH9/SLC9A6/ACTB	79
CC	GO:0032432	actin filament bundle	23/4919	75/19717	0.1555	0.4268	0.3464	FSCN1/ABLIM1/SH2B2/MARCKS/ZYX/FHOD1/MYH10/PDLIM4/TRIP6/CORO1B/PLS1/PDLIM7/LIMCH1/ACTN4/XIRP2/MYH7/CYBA/BAG3/MYH9/CNN2/TPM1/MYH6/ILK	23
CC	GO:0031901	early endosome membrane	43/4919	149/19717	0.1557	0.4268	0.3464	SNX8/RAB31/NTRK2/SLC1A1/NTRK1/FCGR1B/EPHB1/PMEPA1/GPNMB/PML/FGD2/UBXN6/FCGR1A/HLA-H/PDLIM4/GRIPAP1/DTX3L/CD207/HLA-G/CLIP3/STAM/VPS33B/GGA2/ZFYVE9/SH3GL1/PIKFYVE/HLA-E/LITAF/HGS/STX12/LDLRAD4/SNX19/RABGEF1/VTI1B/EEA1/RAB11FIP5/CLVS1/LRP6/SORCS2/ARF6/FZD5/EHD4/SLC9A6	43
CC	GO:0005751	mitochondrial respiratory chain complex IV	5/4919	12/19717	0.1565	0.4268	0.3464	C15orf48/COX6A1/COA3/COX4I1/NDUFA4	5
CC	GO:0030914	STAGA complex	5/4919	12/19717	0.1565	0.4268	0.3464	KAT2A/SUPT3H/TAF6L/TAF10/TADA1	5
CC	GO:0071006	U2-type catalytic step 1 spliceosome	5/4919	12/19717	0.1565	0.4268	0.3464	RBM22/CWC25/MAGOHB/PRPF19/CWC22	5
CC	GO:0071012	catalytic step 1 spliceosome	5/4919	12/19717	0.1565	0.4268	0.3464	RBM22/CWC25/MAGOHB/PRPF19/CWC22	5
CC	GO:0090576	RNA polymerase III transcription factor complex	5/4919	12/19717	0.1565	0.4268	0.3464	GTF3C4/BRF2/GTF3C2/GTF3C6/BDP1	5
CC	GO:1904115	axon cytoplasm	18/4919	57/19717	0.1572	0.4271	0.3467	KIF4A/KIF1C/BLOC1S6/BLOC1S1/BLOC1S4/AP3D1/DTNBP1/FMR1/AP3M2/SNAPIN/MAP1A/NEFL/AP3B2/UCHL1/SPG7/SYBU/MGARP/TERF2	18
CC	GO:0031258	lamellipodium membrane	8/4919	22/19717	0.16	0.4316	0.3503	DOCK8/PDXP/VASP/CFL1/PLXND1/CD44/PIEZO1/SYNE2	8
CC	GO:0097225	sperm midpiece	8/4919	22/19717	0.16	0.4316	0.3503	SQSTM1/HYAL3/CCR6/IFT172/SLC26A6/IFT27/PTCHD3/TACR2	8
CC	GO:0005911	cell-cell junction	124/4919	459/19717	0.1632	0.4375	0.3552	IQGAP3/CDC42EP4/SAPCD2/VEGFA/FSCN1/CDCA3/PTPN6/FRMD4B/PERP/ZYX/YWHAH/DSC2/MYO1E/CEACAM1/PPL/SGSM3/FHOD1/USP53/TJP2/NHS/ANXA2/MYADM/RANGRF/SMAD7/CDC42EP1/CYTH2/FRMD4A/PDLIM4/SCN1B/TIAM1/ARHGEF2/LIMD1/PAK4/PDXP/RAB13/PAK1/PTK7/KCNJ2/ADD3/LIMS1/PKD2/PLEKHA7/AMOT/MPP7/GJD3/PIKFYVE/PDLIM7/ATP1B1/FGF13/CORO1A/MPP5/NDRG1/VASP/PRKCI/PCDH12/CFL1/ITGA6/ACTN4/AMTN/LAT/PKP4/FLOT1/SCRIB/TRAF4/STARD10/SNAP23/CADM1/ILDR1/UBN1/PARK7/IGSF5/ABCB4/S100A11/NRAP/SHROOM1/PTPRM/CDH26/ECT2/WDR1/CDH9/CD99L2/PARD6G/ITK/CD3E/PMP22/CTNNA1/RAPGEF2/CLIC4/SHROOM3/CALB2/DLG5/CLDN7/CD2AP/SIRT2/KRIT1/MYH9/PNN/ARVCF/CNN2/CYTH1/PARD6B/AQP7/AHNAK/ARHGAP17/APC/THEMIS/PARD6A/FZD5/WASF2/LIN7C/WAS/SV2A/CCND1/CDH5/ZAP70/CLDN4/PDZD11/P2RX7/DSC1/MAGI1/ILK/PCDH9/GJA5/SPECC1L	124
CC	GO:1990752	microtubule end	10/4919	29/19717	0.1645	0.4375	0.3552	KIF2C/ASPM/SPAG5/SVIL/MYO5A/MAPRE2/NUMA1/SLAIN2/NCKAP5/CKAP5	10
CC	GO:0101003	ficolin-1-rich granule membrane	19/4919	61/19717	0.1649	0.4375	0.3552	FPR1/RAC1/SERPINB6/SIRPA/LGALS3/SLC2A3/ITGAX/ATP6V0C/TBC1D10C/PRCP/CD58/LILRB2/FPR2/ENPP4/CLEC4D/FCAR/LAMP1/DSC1/CD93	19
CC	GO:0001772	immunological synapse	12/4919	36/19717	0.165	0.4375	0.3552	ICAM1/LGALS3/SCIMP/HAVCR2/EZR/CORO1A/LAT/CD3E/CARD11/MYH9/CD6/ZAP70	12
CC	GO:0008180	COP9 signalosome	12/4919	36/19717	0.165	0.4375	0.3552	HSPA5/HSPA1A/AMOT/LAT/FLOT1/BASP1/EPB41L2/HSPA6/MYH9/HSPA1L/THEMIS/COPS7A	12
CC	GO:0030136	clathrin-coated vesicle	53/4919	188/19717	0.1712	0.4522	0.3671	HBEGF/FURIN/FCGR1B/TFRC/MYO1E/HIP1/CD9/CLTB/SNX9/SLC2A8/HLA-DQB2/AFTPH/LDLR/CTLA4/FCGR1A/CD207/VPS33B/CD74/GGA2/STON2/HIP1R/SLC2A4/NRGN/M6PR/HLA-DPA1/RGS19/BCAP31/HLA-DRA/DVL1/AP1S1/TMED9/AP2S1/LRP1/AAK1/RAB27A/UNC13D/SH3BP4/ABCB4/TMED10/VAMP3/IL7R/HLA-DQA2/CLVS1/LDLRAP1/GOPC/HLA-DPB1/LMBRD1/CLINT1/FZD5/KIAA1107/AP3B2/TYRP1/HLA-DRB1	53
CC	GO:0070382	exocytic vesicle	58/4919	207/19717	0.1717	0.4522	0.3671	ZNRF1/ATP6V0D1/CLTB/SEMA4C/SYN1/SYNGR3/SLC2A8/STX11/HCRT/ATG9A/SYT4/SNAP47/PDE4B/PPT1/RAB3D/STON2/APBA2/TPRG1L/STXBP5/SYNGR2/STX1B/SGTA/PICK1/ROGDI/STX19/TMED9/DTNBP1/SYTL1/STX12/RAB27A/VDAC1/UNC13D/SYT11/VAMP3/STX16/BCL2L1/SNAPIN/MCTP2/LAMP1/VTI1B/SYNGR1/DNM1/PTPRS/STX2/SYTL3/RPH3A/TRAPPC4/RAB15/SYN2/DMXL2/NTF3/KIAA1107/SLC9B2/SYT15/SV2A/SLC40A1/TRIM9/DLG4	58
CC	GO:0043034	costamere	7/4919	19/19717	0.1734	0.455	0.3693	PLEC/SDC4/SVIL/HOMER1/KRT19/AHNAK/ILK	7
CC	GO:0030894	replisome	9/4919	26/19717	0.1786	0.4672	0.3793	TONSL/POLD4/ERCC5/MCM3/PRPF19/CDC5L/PURB/HELB/XPA	9
CC	GO:0031248	protein acetyltransferase complex	28/4919	95/19717	0.1822	0.4698	0.3813	DPF3/PHF10/ING3/ING5/KANSL3/MORF4L2/KANSL1L/ENY2/KAT2A/ACTL6A/YEATS4/SUPT3H/TAF9B/TAF6L/TAF10/NAA16/MCRS1/NAA38/BRPF3/TAF7/KAT6B/DPF1/TAF6/TADA2A/TADA1/ZZZ3/KAT6A/ACTB	28
CC	GO:1902493	acetyltransferase complex	28/4919	95/19717	0.1822	0.4698	0.3813	DPF3/PHF10/ING3/ING5/KANSL3/MORF4L2/KANSL1L/ENY2/KAT2A/ACTL6A/YEATS4/SUPT3H/TAF9B/TAF6L/TAF10/NAA16/MCRS1/NAA38/BRPF3/TAF7/KAT6B/DPF1/TAF6/TADA2A/TADA1/ZZZ3/KAT6A/ACTB	28
CC	GO:0098858	actin-based cell projection	58/4919	208/19717	0.1825	0.4698	0.3813	MYO7A/TIAM2/FSCN1/ACPP/ITGA3/PDGFA/EPHB1/CYFIP1/PVALB/CDK5/BBS2/CEACAM1/NF2/CDH23/HOMER2/DEF6/CNP/MYO5A/ACTG2/HLA-G/ATP6V1E1/ADCY6/TBC1D10C/EPS8L2/FGF13/EZR/VASP/TWF2/ATP6V1A/ITGA6/TUBB3/STARD10/SYTL1/WWOX/FMR1/ICAM2/CD44/CA2/ARL4C/STRC/CLIC4/CALB2/SLC27A4/FZD9/UTRN/ARF6/MYO3B/ACTA2/TMC2/PPP1R9B/RAPH1/CLCA1/RUFY3/TGFB1/CDC42/SYNE2/SPATA13/NGDN	58
CC	GO:0005771	multivesicular body	16/4919	51/19717	0.1827	0.4698	0.3813	NDFIP2/CTSH/CHMP2B/STEAP3/SORL1/ATP13A2/BST2/CD74/SLC2A4/HGS/NAPSA/RAB27A/LAMP1/CHMP1A/CHMP2A/CHMP3	16
CC	GO:0071011	precatalytic spliceosome	16/4919	51/19717	0.1827	0.4698	0.3813	SMU1/EFTUD2/MAGOHB/MFAP1/SART1/PRPF31/SF3B4/SF3B2/WBP4/SNRPB/PRPF3/SNRPD2/CWC22/PHF5A/PRPF38B/LSM2	16
CC	GO:0120111	neuron projection cytoplasm	25/4919	84/19717	0.1841	0.4719	0.383	KIF4A/KIF1C/SFPQ/BLOC1S6/BLOC1S1/HIP1R/BLOC1S4/AP3D1/DTNBP1/FMR1/MAP2K4/AP3M2/SNAPIN/UHMK1/CANX/MAP1A/NEFL/AP3B2/UCHL1/MAPK1/SPG7/SYBU/DLG4/MGARP/TERF2	25
CC	GO:0042575	DNA polymerase complex	6/4919	16/19717	0.1882	0.4808	0.3903	POLD4/POLE/DNA2/MAD2L2/CRCP/POLE2	6
CC	GO:0016592	mediator complex	12/4919	37/19717	0.1917	0.4882	0.3963	MED20/PPARGC1B/HAVCR2/MED4/MED9/MED24/MED22/MED19/MED12L/MED12/MED28/CCNC	12
CC	GO:0034451	centriolar satellite	10/4919	30/19717	0.1945	0.4921	0.3995	SPAG5/PLK1/CCDC66/FLOT1/ZMYND10/BBS9/PIBF1/CEP72/PARD6A/ALDOB	10
CC	GO:0071007	U2-type catalytic step 2 spliceosome	10/4919	30/19717	0.1945	0.4921	0.3995	RBM22/EFTUD2/SNRNP40/SNRPB/PRPF19/CDC5L/SNRPD2/CDC40/CWC22/SYF2	10
CC	GO:0005802	trans-Golgi network	65/4919	236/19717	0.1964	0.4953	0.402	FURIN/RAB31/RAC1/CHAC1/LAP3/GRN/ATP11A/CLTB/PLD4/SNX9/HLA-DQB2/AFTPH/SORL1/ATG9A/PAM/CLIP3/RAB32/RAB13/CD74/GGA2/COG8/NUCB1/COG7/M6PR/PICK1/HLA-DPA1/CLASP2/SLC9A7/CHST7/VPS51/HLA-DRA/AP1S1/PI4K2A/GBA/ARAP1/COG1/TGFBI/GBF1/PLEKHA8/YIPF2/VAMP3/WDR11/VPS52/KIAA1324/STX16/MMP24/RAB38/AP4M1/HLA-DQA2/CORO7/CHID1/PCSK4/COG3/CLVS1/HLA-DPB1/CA4/PCSK5/PLOD3/ATP11C/CNST/CCDC91/HLA-DRB1/ARL5A/CALN1/RAB12	65
CC	GO:0044438	microbody part	29/4919	100/19717	0.2035	0.5061	0.4108	MPV17/ABCD1/ABCD2/FAR2/SLC27A2/HMGCL/EPHX2/PRDX5/ACSL1/ACOX2/TYSND1/ACOT8/GRHPR/AMACR/PEX2/PXMP4/PXMP2/ATAD1/ACSL4/PEX3/PEX5/PEX11A/GSTK1/NUDT19/PECR/PEX13/ACOT6/PEX1/DECR2	29
CC	GO:0044439	peroxisomal part	29/4919	100/19717	0.2035	0.5061	0.4108	MPV17/ABCD1/ABCD2/FAR2/SLC27A2/HMGCL/EPHX2/PRDX5/ACSL1/ACOX2/TYSND1/ACOT8/GRHPR/AMACR/PEX2/PXMP4/PXMP2/ATAD1/ACSL4/PEX3/PEX5/PEX11A/GSTK1/NUDT19/PECR/PEX13/ACOT6/PEX1/DECR2	29
CC	GO:0000800	lateral element	5/4919	13/19717	0.2047	0.5061	0.4108	SMC3/INCENP/BRCA2/RAD51/REC8	5
CC	GO:0000974	Prp19 complex	5/4919	13/19717	0.2047	0.5061	0.4108	RBM22/PRPF19/CDC5L/POLR2A/SYF2	5
CC	GO:0044233	Mitochondria-associated ER Membrane	5/4919	13/19717	0.2047	0.5061	0.4108	MBOAT7/RAB32/RAB38/ACSL4/CANX	5
CC	GO:0099243	extrinsic component of synaptic membrane	5/4919	13/19717	0.2047	0.5061	0.4108	HIP1/KPNA2/TIAM1/STXBP5/SCRIB	5
CC	GO:0008021	synaptic vesicle	53/4919	191/19717	0.2063	0.5084	0.4126	ZNRF1/ATP6V0D1/CLTB/SEMA4C/SYN1/SYNGR3/SLC2A8/STX11/HCRT/ATG9A/SYT4/SNAP47/PDE4B/PPT1/RAB3D/STON2/APBA2/TPRG1L/STXBP5/SYNGR2/STX1B/SGTA/PICK1/ROGDI/STX19/TMED9/DTNBP1/STX12/VDAC1/SYT11/VAMP3/STX16/BCL2L1/SNAPIN/MCTP2/LAMP1/VTI1B/SYNGR1/DNM1/PTPRS/STX2/RPH3A/TRAPPC4/RAB15/SYN2/DMXL2/NTF3/KIAA1107/SLC9B2/SV2A/SLC40A1/TRIM9/DLG4	53
CC	GO:0098636	protein complex involved in cell adhesion	11/4919	34/19717	0.2083	0.5118	0.4154	ITGA2/ITGA3/TSPAN32/CD80/ITGB8/CTLA4/ITGAX/ITGA1/ITGA6/ITGAE/ITGA2B	11
CC	GO:0030990	intraciliary transport particle	9/4919	27/19717	0.212	0.5187	0.4211	TTC30A/IFT122/IFT172/TTC21A/IFT27/WDR19/IFT80/TTC26/CLUAP1	9
CC	GO:0044232	organelle membrane contact site	7/4919	20/19717	0.2125	0.5187	0.4211	MBOAT7/RAB32/RAB38/ACSL4/CANX/PIK3R4/GRAMD1A	7
CC	GO:0005778	peroxisomal membrane	18/4919	60/19717	0.2216	0.5356	0.4347	MPV17/ABCD1/ABCD2/FAR2/SLC27A2/ACSL1/PEX2/PXMP4/PXMP2/ATAD1/ACSL4/PEX3/PEX5/PEX11A/PECR/PEX13/PEX1/DECR2	18
CC	GO:0031903	microbody membrane	18/4919	60/19717	0.2216	0.5356	0.4347	MPV17/ABCD1/ABCD2/FAR2/SLC27A2/ACSL1/PEX2/PXMP4/PXMP2/ATAD1/ACSL4/PEX3/PEX5/PEX11A/PECR/PEX13/PEX1/DECR2	18
CC	GO:0000164	protein phosphatase type 1 complex	4/4919	10/19717	0.2229	0.5356	0.4347	PPP1CB/PPP1R15A/PPP1R9B/PPP1R3B	4
CC	GO:0000815	ESCRT III complex	4/4919	10/19717	0.2229	0.5356	0.4347	CHMP2B/CHMP1A/CHMP2A/CHMP3	4
CC	GO:0036513	Derlin-1 retrotranslocation complex	4/4919	10/19717	0.2229	0.5356	0.4347	DERL1/SYVN1/VCP/RNF139	4
CC	GO:0042641	actomyosin	23/4919	79/19717	0.2305	0.5514	0.4476	FSCN1/ABLIM1/SH2B2/ZYX/FHOD1/MYH10/MYO5A/PDLIM4/TRIP6/CORO1B/PDLIM7/LIMCH1/ACTN4/XIRP2/MYH7/WDR1/CYBA/BAG3/MYH9/CNN2/TPM1/MYH6/ILK	23
CC	GO:0097386	glial cell projection	8/4919	24/19717	0.2318	0.5514	0.4476	SYT4/TMEM50A/PINK1/EZR/FMR1/SIRT2/KCNK2/FYN	8
CC	GO:0099522	region of cytosol	8/4919	24/19717	0.2318	0.5514	0.4476	EIF4EBP1/NCS1/MTOR/HOMER1/HTT/STXBP5/PRKCB/TRIM9	8
CC	GO:0035859	Seh1-associated complex	6/4919	17/19717	0.233	0.5514	0.4476	SEC13/WDR24/NPRL3/SESN2/SEH1L/NPRL2	6
CC	GO:0042599	lamellar body	6/4919	17/19717	0.233	0.5514	0.4476	CTSH/NAPSA/CKAP4/LAMP1/KLK5/ABCA3	6
CC	GO:0031594	neuromuscular junction	22/4919	76/19717	0.2463	0.5809	0.4715	CDK5/SYNGR3/MYH10/TRIP4/DLGAP3/STXBP5/SYNJ2BP/DNAJA3/SYNGR2/STX1B/LRP4/CHRNA1/SYNGR1/MYH9/F2R/KCNC4/UTRN/NEFL/SV2A/LAMA5/P2RX7/DLG4	22
CC	GO:0031430	M band	9/4919	28/19717	0.2476	0.5824	0.4727	ENO1/ANK1/NBR1/SPTBN1/MYBPC3/ALDOA/MYOM1/OBSCN/MYBPC2	9
CC	GO:0071005	U2-type precatalytic spliceosome	15/4919	50/19717	0.2489	0.5827	0.473	SMU1/EFTUD2/MAGOHB/MFAP1/SART1/PRPF31/SF3B4/SF3B2/WBP4/SNRPB/PRPF3/SNRPD2/CWC22/PHF5A/LSM2	15
CC	GO:0030660	Golgi-associated vesicle membrane	32/4919	114/19717	0.2502	0.5827	0.473	SEC13/CLTB/SEC24D/MCFD2/HLA-DQB2/AFTPH/SPPL3/STX5/HLA-H/SEC16A/HLA-G/KDELR2/CNIH2/CD74/NRGN/TMED3/HLA-DPA1/HLA-E/HLA-DRA/AP1S1/COPE/TMED10/HLA-DQA2/ITM2B/VTI1B/GOPC/HLA-DPB1/COPG2/PEF1/HLA-DRB1/SREBF2/USO1	32
CC	GO:0005669	transcription factor TFIID complex	12/4919	39/19717	0.2505	0.5827	0.473	TAF1L/SUPT3H/TAF9B/TAF6L/TAF10/ERCC2/TAF11/GTF2H2/TAF7/TAF6/GTF2H5/ERCC1	12
CC	GO:0005901	caveola	23/4919	80/19717	0.2514	0.5827	0.473	HCK/PTGIS/CORO1C/KIF18A/PTCH1/LRP8/ADTRP/RANGRF/SRC/HMOX1/HTR2A/MYOF/ATP1B1/FLOT1/ATP2B4/ATP1B3/CTNNA1/ASAH2/F2R/LRP6/INSR/MAPK1/TFPI	23
CC	GO:0031089	platelet dense granule lumen	5/4919	14/19717	0.2569	0.5827	0.473	CTSW/ITIH3/RARRES2/TIMP3/SERPINA4	5
CC	GO:0032300	mismatch repair complex	5/4919	14/19717	0.2569	0.5827	0.473	MSH6/PMS2P1/PMS2P5/MLH3/PMS1	5
CC	GO:0033646	host intracellular part	5/4919	14/19717	0.2569	0.5827	0.473	GBP2/FMR1/SCO1/CNOT7/GBP4	5
CC	GO:0038201	TOR complex	5/4919	14/19717	0.2569	0.5827	0.473	MTOR/TTI1/MAPKAP1/SESN2/MLST8	5
CC	GO:0043218	compact myelin	5/4919	14/19717	0.2569	0.5827	0.473	ANXA2/MPP5/PRKCI/PMP22/SIRT2	5
CC	GO:0043656	intracellular region of host	5/4919	14/19717	0.2569	0.5827	0.473	GBP2/FMR1/SCO1/CNOT7/GBP4	5
CC	GO:0045239	tricarboxylic acid cycle enzyme complex	5/4919	14/19717	0.2569	0.5827	0.473	MRPS36/BCKDK/OGDH/KAT2A/DLST	5
CC	GO:0099523	presynaptic cytosol	5/4919	14/19717	0.2569	0.5827	0.473	NCS1/HTT/STXBP5/PRKCB/TRIM9	5
CC	GO:0005795	Golgi stack	41/4919	149/19717	0.2606	0.5859	0.4756	TMEM87A/SGMS1/SULF2/CIT/CANT1/GALNT2/CHPF2/ASAP2/MGAT4B/SORL1/CSGALNACT1/CLIP3/LPCAT2/NECAB3/PITPNM1/NUCB1/TMED3/GALNT1/B3GALT6/BCAP31/GAL3ST2/ARAP1/B4GALNT4/TMEM115/GBF1/ST3GAL3/YIPF2/STX16/CHPF/B4GALT5/COG3/NSFL1C/TRAPPC4/FUT6/RAB34/GAL3ST4/XYLT1/TOM1L1/B4GALT4/B4GALT7/USO1	41
CC	GO:0000407	phagophore assembly site	10/4919	32/19717	0.2609	0.5859	0.4756	SQSTM1/NBR1/ATG9A/ULK1/STX12/ATG2B/PIK3C3/WDR45/ATG7/RAB1B	10
CC	GO:0031941	filamentous actin	10/4919	32/19717	0.2609	0.5859	0.4756	SMTN/ACTG1/PDLIM4/PKD2/PDLIM7/DUSP22/CD2AP/MYO18B/RAC3/SPECC1L	10
CC	GO:0098793	presynapse	129/4919	491/19717	0.2613	0.5859	0.4756	ZNRF1/SLC29A2/ITGA2/FOSL1/ADORA2A/NTRK2/MICAL1/PPFIA4/CYFIP1/ATP6V0D1/RIMS3/CDK5/HIP1/C1QL1/CLTB/SEMA4C/SYN1/SYAP1/SYNGR3/SLC2A8/NCS1/SLC29A1/ACTG1/STX11/HCRT/BLOC1S6/P2RX1/ATG9A/SYT4/SNAP47/HTR2A/PDE4B/SRI/PPT1/KCNA3/RAB3D/SNAP29/PFN2/HTT/STON2/SLC2A4/SH3GL1/RNF40/APBA2/TPRG1L/CCK/STXBP5/SYNGR2/CASR/STX1B/SGTA/PICK1/DVL1/AP3D1/ROGDI/FLOT1/AP1S1/SCRIB/STX19/PI4K2A/DRD1/PNISR/TMED9/ATP2B4/AAK1/SNAP23/DTNBP1/SLC4A10/TANC1/STX12/WNT7A/PPFIA3/CNR1/NTSR1/VDAC1/PARK7/ELK1/FMR1/DNAJC6/SYT11/VAMP3/STX16/CDH9/BCL2L1/ERC2/CALB2/SNAPIN/MCTP2/LAMP1/NLGN4Y/VTI1B/SYNGR1/DNM1/KCNC4/PTPRS/STX2/CANX/RPH3A/DOC2B/TRAPPC4/PRKCB/PACSIN1/P2RY1/C1QBP/RAB15/ARF6/SYN2/CACNB2/CTBP1/FBXL20/NEFL/DMXL2/NTF3/NPFF/KIAA1107/SLC9B2/LIN7C/RTN4R/SV2A/KCNK2/SLC40A1/PDZD11/P2RX7/RPL22/TRIM9/DLG4/ILK/SLC9A6/ACTB	129
CC	GO:0043292	contractile fiber	63/4919	234/19717	0.2631	0.5881	0.4774	PLEC/SDC4/SQSTM1/TIMP4/SCO2/PDE4DIP/ENO1/CORO1C/CAPZB/ANK1/SVIL/ACTG1/NBR1/MYLK2/TMOD2/PDLIM4/HOMER1/PDE4B/SRI/PAK1/MYOT/MYL1/PDLIM7/SPTBN1/TWF2/PARVB/ACTN4/TPM2/C10orf71/MYBPC3/FKBP1A/ATP2B4/MYH7B/XIRP2/MYH7/NRAP/TNNC1/MYH4/SCO1/TRIM54/IDO1/BAG3/KRT19/MYL6B/DNAJB6/ALDOA/MYOM1/OBSCN/BMP10/AHNAK/TPM1/MYO18B/FBXL22/PPP1R12B/PYROXD1/ACTA2/SMN1/MYH6/TCAP/MYBPC2/PPP1R12A/SYNE2/ILK	63
CC	GO:0032588	trans-Golgi network membrane	26/4919	92/19717	0.2652	0.5911	0.4798	RAB31/PLD4/HLA-DQB2/AFTPH/CLIP3/CD74/COG8/COG7/M6PR/PICK1/HLA-DPA1/VPS51/HLA-DRA/AP1S1/COG1/VAMP3/VPS52/STX16/MMP24/AP4M1/HLA-DQA2/COG3/CLVS1/HLA-DPB1/HLA-DRB1/CALN1	26
CC	GO:0031902	late endosome membrane	37/4919	134/19717	0.266	0.5912	0.4799	NDFIP2/CD68/NTRK1/CHMP2B/AP5S1/UBXN6/ANXA2/HLA-DMA/SNF8/ATG9A/ATP13A2/VPS33B/PIKFYVE/MICALL1/TMEM106B/HLA-DRA/LITAF/IFITM3/HGS/RAB27A/SLC38A9/YIPF2/KIAA1324/HLA-DMB/SLC29A3/ABCA5/LAMP1/VTI1B/LAMTOR4/CHMP2A/LAMTOR2/LAPTM4A/VPS39/MITD1/HLA-DRB1/CHMP3/OSBPL9	37
CC	GO:0098798	mitochondrial protein complex	70/4919	262/19717	0.2736	0.6063	0.4922	PPIF/C15orf48/MRPL37/MRPL28/BAX/MRPL51/TIMM17A/MRPS36/BCKDK/MRPL22/MRPL18/MRPS5/TIMM10/MRPS18C/MRPS11/NDUFB11/MICU1/COX6A1/UQCRC1/NSUN4/NDUFB8/C12orf65/MRPS6/TIMM22/TIMM50/ROMO1/TOMM6/COA3/MRPL20/NDUFS1/DLAT/CHCHD6/GRPEL1/MRPL50/MRPL36/MRPS2/NDUFS7/VDAC1/MRPL35/MRPL27/MRPL15/MTX3/NDUFB10/MRPL34/NDUFC1/MRPS14/MRPL13/IMMP1L/MTG1/NDUFA9/COX4I1/DNA2/MRPL10/NDUFA12/TRMT10C/MRPL54/DAP3/PAM16/MRPL2/TOMM22/AGK/MRPL39/NDUFA4/NDUFB2/NDUFA13/SPG7/MRPL43/TIMM9/MRPL48/MALSU1	70
CC	GO:0030016	myofibril	60/4919	224/19717	0.2843	0.6144	0.4987	PLEC/SDC4/SQSTM1/TIMP4/SCO2/PDE4DIP/ENO1/CORO1C/CAPZB/ANK1/SVIL/ACTG1/NBR1/MYLK2/TMOD2/PDLIM4/HOMER1/PDE4B/SRI/PAK1/MYOT/MYL1/PDLIM7/SPTBN1/TWF2/PARVB/ACTN4/TPM2/C10orf71/MYBPC3/FKBP1A/ATP2B4/MYH7B/XIRP2/MYH7/NRAP/TNNC1/MYH4/SCO1/TRIM54/BAG3/KRT19/DNAJB6/ALDOA/MYOM1/OBSCN/BMP10/AHNAK/TPM1/MYO18B/FBXL22/PPP1R12B/PYROXD1/SMN1/MYH6/TCAP/MYBPC2/PPP1R12A/SYNE2/ILK	60
CC	GO:0002116	semaphorin receptor complex	4/4919	11/19717	0.2852	0.6144	0.4987	PLXNB2/PLXNB1/PLXNA1/PLXND1	4
CC	GO:0002178	palmitoyltransferase complex	4/4919	11/19717	0.2852	0.6144	0.4987	SPTSSA/ORMDL2/ZDHHC9/ORMDL3	4
CC	GO:0032797	SMN complex	4/4919	11/19717	0.2852	0.6144	0.4987	FMR1/DDX20/SMN1/GEMIN5	4
CC	GO:0034992	microtubule organizing center attachment site	4/4919	11/19717	0.2852	0.6144	0.4987	SUN2/SPAG4/SYNE3/SYNE2	4
CC	GO:0034993	meiotic nuclear membrane microtubule tethering complex	4/4919	11/19717	0.2852	0.6144	0.4987	SUN2/SPAG4/SYNE3/SYNE2	4
CC	GO:0043220	Schmidt-Lanterman incisure	4/4919	11/19717	0.2852	0.6144	0.4987	ANXA2/MPP5/PRKCI/SIRT2	4
CC	GO:0106083	nuclear membrane protein complex	4/4919	11/19717	0.2852	0.6144	0.4987	SUN2/SPAG4/SYNE3/SYNE2	4
CC	GO:0106094	nuclear membrane microtubule tethering complex	4/4919	11/19717	0.2852	0.6144	0.4987	SUN2/SPAG4/SYNE3/SYNE2	4
CC	GO:1990907	beta-catenin-TCF complex	4/4919	11/19717	0.2852	0.6144	0.4987	TLE4/TCF7L2/TLE3/LDB1	4
CC	GO:0031985	Golgi cisterna	32/4919	116/19717	0.2867	0.6158	0.4998	TMEM87A/SGMS1/CIT/CANT1/GALNT2/CHPF2/ASAP2/SORL1/CSGALNACT1/NECAB3/PITPNM1/NUCB1/TMED3/GALNT1/B3GALT6/BCAP31/GAL3ST2/ARAP1/B4GALNT4/TMEM115/ST3GAL3/YIPF2/STX16/CHPF/B4GALT5/COG3/FUT6/RAB34/GAL3ST4/XYLT1/B4GALT4/B4GALT7	32
MF	GO:0044389	ubiquitin-like protein ligase binding	121/4733	308/17697	9.154e-07	0.001088	0.00102	EGR2/TXNIP/UBE2C/CDKN1A/SQSTM1/AURKA/TPI1/TRIB1/UBE2A/RFFL/TUBA1B/DNAJA1/YWHAE/PML/YWHAZ/SNX9/GPI/HSPA5/HSPA1A/SKI/DERL1/UBE2B/MAP1LC3A/SMG5/DET1/BAG4/ACTG1/TUBB/SMAD7/CCNB1/SRC/MOAP1/DTX3L/RPL5/SUMO4/HSPA9/ARRB1/VCP/TRIP4/CLU/STAM/USP19/UBB/PSMD1/FZD6/SUMO3/UQCRC1/UBE2N/AMBRA1/ATP6V0C/SMAD6/UBXN1/NPLOC4/RPS27A/FOXO1/RNF40/TOLLIP/BID/RPL23/PINK1/PIAS1/TRIOBP/PA2G4/UBA52/CCDC50/ZNF746/TRAF4/TANK/AICDA/RALA/MID1/RNF8/HGS/SUMO1/FZD8/JUN/JKAMP/SLC25A5/CKB/NFKBIA/TRAF1/SYT11/CEBPB/PIAS2/CUL5/DTX1/WRAP53/BAG2/TRAF2/PRDX6/PIAS4/EIF4E2/LRPPRC/KCNH2/TNFRSF1B/NAE1/HSPA1L/ARRDC1/PRKACB/CHEK2/TRAF6/PSMA3/APC/STAT1/RPL11/PER3/AXIN2/RALB/FZD5/ZNF675/HERC2/CUL4A/POLR2A/GLMN/UBOX5/UCHL1/GGN/TRIB3/UBE2W/MAGEA2B/JAK1	121
MF	GO:0031625	ubiquitin protein ligase binding	111/4733	290/17697	1.031e-05	0.006127	0.005739	EGR2/TXNIP/CDKN1A/SQSTM1/AURKA/TPI1/TRIB1/UBE2A/RFFL/TUBA1B/DNAJA1/YWHAE/PML/YWHAZ/SNX9/GPI/HSPA5/HSPA1A/SKI/DERL1/UBE2B/MAP1LC3A/SMG5/DET1/BAG4/ACTG1/TUBB/SMAD7/SRC/MOAP1/RPL5/HSPA9/ARRB1/VCP/CLU/USP19/UBB/PSMD1/FZD6/UQCRC1/UBE2N/AMBRA1/ATP6V0C/SMAD6/UBXN1/NPLOC4/RPS27A/FOXO1/RNF40/TOLLIP/BID/RPL23/PINK1/PIAS1/TRIOBP/PA2G4/UBA52/CCDC50/ZNF746/TRAF4/TANK/AICDA/RALA/MID1/RNF8/SUMO1/FZD8/JUN/JKAMP/SLC25A5/CKB/NFKBIA/TRAF1/SYT11/PIAS2/CUL5/DTX1/WRAP53/BAG2/TRAF2/PRDX6/PIAS4/EIF4E2/LRPPRC/KCNH2/TNFRSF1B/NAE1/HSPA1L/ARRDC1/PRKACB/CHEK2/TRAF6/PSMA3/APC/RPL11/PER3/AXIN2/RALB/FZD5/ZNF675/HERC2/CUL4A/POLR2A/GLMN/UBOX5/UCHL1/GGN/TRIB3/UBE2W/MAGEA2B/JAK1	111
MF	GO:0008017	microtubule binding	93/4733	246/17697	8.832e-05	0.03501	0.03279	KIF20A/KIF2C/KIF14/SKA1/KIFC1/KIF4A/FAM83D/KIF15/GAS2L1/BIRC5/MAP6/KIF23/FES/KIF24/KIF20B/GAPDH/NUSAP1/EML4/GAS2L3/KIF1C/LZTS1/SPAG5/RACGAP1/KIF18A/MX1/KIF11/MAP1LC3A/PLK1/CCDC66/UXT/FSD1/PSRC1/TPPP/MAPRE2/CENPE/NUMA1/TIAM1/ARHGEF2/CLIP3/REEP4/KIF4B/JAKMIP1/KLC3/RPS3/SUN2/MDM1/TERF1/TUBGCP2/FGF13/EZR/NDRG1/EML5/CLASP2/MAST2/SBDS/MID1/KIF3C/CHP1/MID2/HOOK2/PPP5C/FMR1/MAP1S/MARK4/RAE1/PRC1/TRIM54/CCDC88B/KATNAL2/S100A8/DNM1/LRPPRC/KRIT1/PRNP/CETN2/CCDC69/MAP1A/APC/MAP9/CETN3/ARL3/WHAMM/OGG1/KIF26B/STARD9/TUBGCP5/FMN1/KIF19/SYBU/CKAP5/KIFC2/REEP1/TUBGCP3	93
MF	GO:0003735	structural constituent of ribosome	78/4733	202/17697	0.0001435	0.03514	0.03292	RPL3/MRPL37/MRPL28/RPS8/RPL32/RPS25/RPS12/RPL10A/RPS18/RPS27/MRPL51/MRPS36/RPL35/RPL38/RPS10/RPS3A/RPLP2/RPL21/MRPL22/RPL19/RPL23A/RPS5/RPL36/RPL5/RPL4/RPL30/MRPL18/RPL27A/RPL26/MRPS5/RPS23/RPS6/RPS15/MRPS18C/RPL36A/MRPS11/RPL7/RPL18A/RPS13/RPS20/RPL6/RPS3/RPS15A/RPS27A/MRPS6/RPL23/RPS11/RPS19/UBA52/RPS16/MRPL20/RPS9/RPL14/RPL37A/MRPL36/MRPS2/RPL37/MRPL35/MRPL27/MRPL15/MRPS25/RPL29/MRPL34/RPS4X/RPL12/MRPS14/MRPL13/RPSA/RPS28/MRPL10/RPL7A/RPL39/MRPL54/DAP3/MRPL2/RPL11/MRPL43/RPL22	78
MF	GO:0015631	tubulin binding	120/4733	336/17697	0.0001654	0.03514	0.03292	KIF20A/KIF2C/KIF14/SKA1/KIFC1/KIF4A/FAM83D/KIF15/GAS2L1/BIRC5/MAP6/KIF23/FES/KIF24/KIF20B/GAPDH/NUSAP1/EML4/GAS2L3/KIF1C/LZTS1/SPAG5/RACGAP1/KIF18A/SMC3/MX1/ATF5/BRCA2/KIF11/MAP1LC3A/PLK1/CCDC66/CENPJ/UXT/FSD1/PSRC1/B9D2/TPPP3/TPPP/MAPRE2/CENPE/NUMA1/TIAM1/ARHGEF2/CLIP3/REEP4/KIF4B/PDE4B/JAKMIP1/FAM110C/KLC3/RPS3/SUN2/HTT/PDCD5/STMN3/CCT5/MDM1/TERF1/TUBGCP2/FGF13/CEP70/EZR/NDRG1/EML5/STMN1/CLASP2/MAST2/SBDS/MID1/KIF3C/CHP1/MID2/HOOK2/EMD/AGTPBP1/PPP5C/FMR1/MAP1S/MARK4/SYT11/RAE1/PRC1/TRIM54/ARL4C/NDN/BEX4/CCDC88B/ALDOA/KATNAL2/S100A8/DNM1/LRPPRC/KRIT1/PRNP/RAB11FIP5/CETN2/CCDC69/MAP1A/TBCEL/APC/MAP9/EFHC1/CETN3/ARL3/WHAMM/OGG1/BCAS3/KIF26B/STARD9/TUBGCP5/ADNP/FMN1/KIF19/SYBU/CKAP5/FYN/KIFC2/REEP1/TUBGCP3	120
MF	GO:0015932	nucleobase-containing compound transmembrane transporter activity	23/4733	43/17697	0.0001773	0.03514	0.03292	SLC29A2/SLC35A2/SLC35E4/SLC29A1/SLC25A23/ABCD1/SLC35B1/HNRNPA3/SLC25A25/SLC35D2/SLC35D1/SLC35B2/SLC35E3/SLC25A5/SLC35C1/SIDT2/SLC29A3/SLC25A36/SLC33A1/SLC25A42/SLC35B4/SLC25A4/SLC28A1	23
MF	GO:0070181	small ribosomal subunit rRNA binding	9/4733	11/17697	0.0002212	0.03757	0.03519	MRPS18C/MRPS11/RPS13/RPS3/NSUN4/CIRBP/MRPS6/UTP23/RBM3	9
MF	GO:0016776	phosphotransferase activity, phosphate group as acceptor	21/4733	39/17697	0.0002983	0.0404	0.03784	TJP2/CMPK2/PMVK/DTYMK/AK5/AK3/NME4/NME3/PPIP5K1/AK4/LRGUK/CARD11/GUK1/IP6K1/AK1/CMPK1/IP6K2/NME9/AK2/IP6K3/NME2	21
MF	GO:0019843	rRNA binding	30/4733	63/17697	0.0003058	0.0404	0.03784	RPL3/RPS18/RPL23A/TST/RPS5/RPL5/MRPL18/MRPS18C/MRPS11/RPS13/RPS3/NSUN4/CIRBP/MRPS6/RPL23/RPS11/FASTKD2/SBDS/MRPL20/RPS9/RPL37/RPS4X/EMG1/RPL12/UTP23/PTCD3/RPL11/NGRN/RPF1/RBM3	30
MF	GO:0032356	oxidized DNA binding	8/4733	10/17697	0.0006828	0.08119	0.07604	MSH6/RPS3/RECQL4/POT1/XRCC1/OGG1/WRN/MUTYH	8
MF	GO:0003714	transcription corepressor activity	86/4733	238/17697	0.0008612	0.09186	0.08604	E2F7/E2F8/RELB/RBBP8/ARID5A/TLE4/ATF3/GMNN/CBFA2T3/ATF5/SIRT6/HSPA1A/SKI/CCAR1/CENPJ/UXT/TLE2/FOXP3/DRAP1/RYBP/ALX1/TONSL/NAB2/LIMD1/KLF12/AEBP1/URI1/WWTR1/PBXIP1/ARHGAP35/BCOR/BHLHE40/ZNF85/PFDN5/TRIM22/CBFA2T2/LMCD1/SMARCA4/KDM5B/PIAS1/ZBTB32/TLE3/CDYL2/EZH2/TAF9B/HSF4/ZNF653/DDIT3/ZNF281/KCTD1/CASP8AP2/ZHX2/BASP1/TFAP2B/RCOR3/MIER2/TOB2/MXD4/MYBBP1A/DDX54/CITED2/YAP1/SIAH2/RLIM/CNOT7/NPAT/CDYL/PIAS4/BHLHE41/C1QBP/MTA1/CTBP1/HDAC9/MSC/IRF2BP1/MTA3/MXI1/POU4F1/ZNF451/RARA/CCND1/LDB1/NCOR1/UBP1/TRIB3/SIRT1	86
MF	GO:0004674	protein serine/threonine kinase activity	147/4733	439/17697	0.0009275	0.09186	0.08604	AURKB/PKMYT1/PBK/MAPK11/BUB1B/TTK/CDK1/WNK1/SQSTM1/AURKA/LMTK3/CIT/MELK/NEK2/TTBK1/PIM3/BUB1/DYRK3/DAPK2/CAMK1/CDK5/CDC42BPG/BMP2K/PLK4/PLK2/LRRK1/AKT3/PLK1/MTOR/BCKDK/CAMKV/MAST4/MYLK2/PIM1/RIPK3/MAP3K6/MAP2K3/PAK4/PIM2/CCL3/CDK2/MAP3K2/CAMK2A/MAPK12/ICK/PAK1/ADCK1/NUAK2/MAP2K6/FAM20C/CDK14/STK19/STK16/IRAK3/PRKX/PAK3/SIK3/CDK18/CDK7/PRKAB2/TAF1L/MAP3K5/PINK1/PRKD3/KSR2/PRKCA/STRADB/STK3/PRKCI/BRD4/DYRK4/NRK/CDK10/RIOK1/MAST2/ULK1/PNCK/FASTK/SNRK/MAP3K11/AAK1/IRAK1/LIMK1/LIMK2/TAOK3/PRKAG2/STK25/MKNK1/ERCC2/ACVR1C/ACVR2B/CHEK1/MARK4/CCNK/CAMK2G/GTF2H2/PRKCE/MAP3K3/GTF2H1/MINK1/NEK1/SPEG/MAP2K4/NEK8/GSK3A/PHKG2/BRSK2/BRAF/DAPK1/SGK2/RPS6KL1/EIF2AK3/CAMK2D/MAP4K1/CLK3/ERN1/RIPK2/MAPKAPK2/OBSCN/UHMK1/STK32C/GRK5/MNAT1/PRKCB/PRKACB/ATR/CHEK2/STK38/PIK3R4/AKAP13/BCR/MYO3B/TSSK3/STK17B/ATM/CDKL2/GRK6/NEK9/MAP3K9/CLK2/CSNK1G2/SBK1/MAPK1/NME2/PAK2/ILK/PSKH2	147
MF	GO:0004896	cytokine receptor activity	40/4733	96/17697	0.00106	0.09186	0.08604	EBI3/CSF2RB/IL1R1/CXCR6/CSF3R/CCR1/CCRL2/IL2RA/IL2RB/IL17RE/IL1R2/IL4R/CCR6/CCR2/CCR4/IL2RG/IL12RB2/IL9R/CD74/IL21R/CCR5/FLT3/GPR35/IL15RA/CSF2RA/IL12RB1/IL27RA/IL17RD/IL18R1/IL17RC/CD44/IL5RA/IL7R/CCR8/IL11RA/IFNGR1/F3/IL10RA/CXCR5/CX3CR1	40
MF	GO:0060589	nucleoside-triphosphatase regulator activity	118/4733	344/17697	0.001082	0.09186	0.08604	RGS16/TIAM2/GPSM2/RINL/ARHGAP23/GPSM1/ADPRH/SIPA1L1/SIRPA/RACGAP1/DNAJA1/SGSM3/ELMOD1/DEPDC1B/RTKN/TBC1D9/PLXNB1/SRGAP2/SIPA1L2/RGPD2/CDC42SE1/ASAP2/ARHGAP9/TBC1D2B/ARHGEF12/ARHGAP11A/ARRB1/AHSA1/RIC8A/DOCK1/ARHGAP31/TBC1D22A/ARHGAP19/DOCK5/ARHGAP35/TBC1D10C/STARD13/ARHGAP5/STXBP5/RASAL2/PREX1/DNAJA3/RUNDC1/ATP1B1/TBC1D3H/TBC1D20/ARHGAP4/TBC1D10B/RASA3/VPS9D1/RALGDS/TBC1D8/MYBPC3/ARAP1/GRPEL1/THY1/AGAP5/NCAPH/ADAP2/ARHGAP15/ACAP1/SRGAP3/JUN/ARAP3/SH3BP4/ATP1B3/RASA4/TBC1D22B/AGAP2/ARHGAP33/ECT2/NUP50/TBC1D2/MYO9B/RGS1/BAG3/RASAL1/BRSK2/RAPGEF2/CHN1/BAG2/NPRL3/DNAJB6/RAP1GAP2/KRIT1/ARL2BP/DNAJC24/TBC1D13/GNAQ/TBCK/ARHGAP18/ARHGDIA/ARHGAP17/TBC1D3C/RGS5/BCR/RIN2/DNAJB4/ARL2/ARHGAP24/CHN2/ARHGAP1/DEPDC1/RIC8B/ARHGAP32/ALS2CL/PLCB1/WAS/BNIP2/PGAM5/DNAJB2/RGPD1/RALGAPA1/SESN2/GDI1/RALBP1/RGS7/NPRL2	118
MF	GO:0017048	Rho GTPase binding	66/4733	177/17697	0.001312	0.104	0.09742	IQGAP3/CDC42EP4/TIAM2/ANLN/PLEKHG2/ARHGEF39/ARHGEF40/CYFIP1/CORO1C/RTKN/ARHGEF18/NOXA1/SRGAP2/FGD2/CDC42SE1/SRGAP2B/MCF2L2/CDC42EP1/ARHGEF12/ARHGEF5/TNFAIP1/TIAM1/ARHGEF2/PAK4/DOCK1/DVL3/WHAMMP3/PAK1/FMNL1/DOCK3/RASGRF2/PAK3/PREX1/PLEKHG1/EPS8L2/VAV2/ARHGAP4/TRIOBP/DIAPH3/PLEKHG7/DVL1/MAP3K11/SRGAP3/ECT2/MYO9B/PARD6G/KCTD13/OBSCN/CDC42SE2/PARD6B/ARHGDIA/ARHGAP17/AKAP13/BCR/PARD6A/WHAMM/MCF2L/C15orf62/WAS/STRN3/NET1/SPATA13/PPP6R1/RALBP1/PAK2/ARHGEF26	66
MF	GO:0030228	lipoprotein particle receptor activity	10/4733	15/17697	0.001402	0.1042	0.09762	LRP8/LDLR/SORL1/LRP10/CXCL16/LRP1/ILDR1/LRP12/LRP6/APOBR	10
MF	GO:0042393	histone binding	72/4733	197/17697	0.001532	0.1071	0.1003	HJURP/ASF1B/PHF19/UHRF1/PTMA/NCAPD2/CHAF1B/DPF3/MSH6/ING1/PHF10/SPTY2D1/NASP/ING3/NAP1L2/ING5/CKS2/MCM2/CBX5/DTX3L/TONSL/TP53BP1/PRMT7/CKS1B/CD1D/PHIP/CBX8/CARM1/TAF1L/SMARCA4/KDM5B/BRD4/CDYL2/CBX2/SUPT6H/FAM156B/RNF8/KDM8/FMR1/ATAD2/VPS72/NPM3/PHF13/SAP30L/BRD9/RCC1/MBTD1/MLLT6/CDYL/WRAP53/TAF7/KAT6B/WDR5B/MLLT3/KDM5A/DPF1/PRKCB/PYGO1/BAZ2A/SPHK2/RRP8/STAT1/UHRF2/RAG2/BCAS3/ASF1A/PHF8/LRWD1/RNF168/KAT6A/SPIN1/SIRT1	72
MF	GO:0017116	single-stranded DNA-dependent ATP-dependent DNA helicase activity	12/4733	20/17697	0.00177	0.1107	0.1037	MCM5/RAD51/MCM2/PIF1/POLQ/RFC2/MCM7/HELQ/DSCC1/CHTF8/DNA2/HELB	12
MF	GO:0043142	single-stranded DNA-dependent ATPase activity	12/4733	20/17697	0.00177	0.1107	0.1037	MCM5/RAD51/MCM2/PIF1/POLQ/RFC2/MCM7/HELQ/DSCC1/CHTF8/DNA2/HELB	12
MF	GO:0031386	protein tag	8/4733	11/17697	0.001914	0.1113	0.1043	ISG15/SUMO4/UBB/SUMO3/RPS27A/UBA52/SUMO1/UBL5	8
MF	GO:0031267	small GTPase binding	146/4733	443/17697	0.001966	0.1113	0.1043	IQGAP3/CDC42EP4/TIAM2/ANLN/PLEKHG2/ARHGEF39/BIRC5/ADPRH/MICAL1/RAC1/ARHGEF40/RASGEF1B/CYFIP1/RAB11FIP1/RIMS3/SBF1/ANXA2P2/CORO1C/SGSM3/RTKN/TBC1D9/ARHGEF18/NOXA1/SRGAP2/FGD2/RGPD2/CDC42SE1/ANXA2/SRGAP2B/RANGRF/MCF2L2/CDC42EP1/CSE1L/SORL1/MYO5A/TBC1D2B/ARHGEF12/ARHGEF5/TNFAIP1/TIAM1/ARHGEF2/MAPKAP1/PAK4/DOCK1/RAPGEF5/DVL3/TBC1D22A/WHAMMP3/PAK1/GGA2/FMNL1/DOCK3/TBC1D10C/STK19/RASGRF2/PAK3/MICALL1/STXBP5/PREX1/RUNDC1/SBF2/PLEKHG1/HPS4/TBC1D3H/EPS8L2/VAV2/TBC1D20/NDRG1/RILPL2/ARHGAP4/TBC1D10B/TRIOBP/SH3BP5L/DIAPH3/PLEKHG7/ABCA1/DVL1/ULK1/XPO6/TBC1D8/MAP3K11/SYTL1/RASGRP4/RAPGEF1/SRGAP3/UNC13D/SH3BP4/RAB11FIP3/TBC1D22B/YIPF2/DENND2D/ECT2/VPS52/RABGGTB/NUP50/TBC1D2/MYO9B/PARD6G/RCC1/RABGEF1/MICAL3/RGL3/RAPGEF2/PEX5/KCTD13/RALGPS1/RAB11FIP5/RAB11FIP4/LZTR1/OBSCN/DENND3/SYTL3/RPH3A/TRAPPC4/CDC42SE2/PARD6B/TBC1D13/SPHK2/TBCK/ARHGDIA/ARHGAP17/TBC1D3C/RAB34/AKAP13/BCR/RIN2/PARD6A/DMXL2/WHAMM/ARHGAP1/MCF2L/C15orf62/WAS/STRN3/NET1/RGPD1/DENND6A/RUSC2/TNPO1/GDI1/SPATA13/PPP6R1/RALBP1/PAK2/ARHGEF26/LSM2	146
MF	GO:0030695	GTPase regulator activity	104/4733	304/17697	0.002266	0.1225	0.1147	RGS16/TIAM2/GPSM2/RINL/ARHGAP23/GPSM1/ADPRH/SIPA1L1/SIRPA/RACGAP1/SGSM3/ELMOD1/DEPDC1B/RTKN/TBC1D9/PLXNB1/SRGAP2/SIPA1L2/RGPD2/CDC42SE1/ASAP2/ARHGAP9/TBC1D2B/ARHGEF12/ARHGAP11A/ARRB1/RIC8A/DOCK1/ARHGAP31/TBC1D22A/ARHGAP19/DOCK5/ARHGAP35/TBC1D10C/STARD13/ARHGAP5/STXBP5/RASAL2/PREX1/DNAJA3/RUNDC1/TBC1D3H/TBC1D20/ARHGAP4/TBC1D10B/RASA3/VPS9D1/RALGDS/TBC1D8/ARAP1/THY1/AGAP5/ADAP2/ARHGAP15/ACAP1/SRGAP3/JUN/ARAP3/SH3BP4/RASA4/TBC1D22B/AGAP2/ARHGAP33/ECT2/NUP50/TBC1D2/MYO9B/RGS1/RASAL1/RAPGEF2/CHN1/NPRL3/RAP1GAP2/KRIT1/ARL2BP/TBC1D13/GNAQ/TBCK/ARHGAP18/ARHGDIA/ARHGAP17/TBC1D3C/RGS5/BCR/RIN2/ARL2/ARHGAP24/CHN2/ARHGAP1/DEPDC1/RIC8B/ARHGAP32/ALS2CL/PLCB1/WAS/BNIP2/PGAM5/RGPD1/RALGAPA1/SESN2/GDI1/RALBP1/RGS7/NPRL2	104
MF	GO:0017016	Ras GTPase binding	141/4733	429/17697	0.002603	0.1346	0.126	IQGAP3/CDC42EP4/TIAM2/ANLN/PLEKHG2/ARHGEF39/BIRC5/ADPRH/MICAL1/RAC1/ARHGEF40/RASGEF1B/CYFIP1/RAB11FIP1/RIMS3/SBF1/ANXA2P2/CORO1C/SGSM3/RTKN/TBC1D9/ARHGEF18/NOXA1/SRGAP2/FGD2/RGPD2/CDC42SE1/ANXA2/SRGAP2B/RANGRF/MCF2L2/CDC42EP1/CSE1L/MYO5A/TBC1D2B/ARHGEF12/ARHGEF5/TNFAIP1/TIAM1/ARHGEF2/MAPKAP1/PAK4/DOCK1/RAPGEF5/DVL3/TBC1D22A/WHAMMP3/PAK1/FMNL1/DOCK3/TBC1D10C/STK19/RASGRF2/PAK3/MICALL1/STXBP5/PREX1/RUNDC1/SBF2/PLEKHG1/HPS4/TBC1D3H/EPS8L2/VAV2/TBC1D20/NDRG1/ARHGAP4/TBC1D10B/TRIOBP/SH3BP5L/DIAPH3/PLEKHG7/DVL1/ULK1/XPO6/TBC1D8/MAP3K11/SYTL1/RASGRP4/RAPGEF1/SRGAP3/UNC13D/SH3BP4/RAB11FIP3/TBC1D22B/YIPF2/DENND2D/ECT2/VPS52/RABGGTB/NUP50/TBC1D2/MYO9B/PARD6G/RCC1/RABGEF1/MICAL3/RGL3/RAPGEF2/KCTD13/RALGPS1/RAB11FIP5/RAB11FIP4/LZTR1/OBSCN/DENND3/SYTL3/RPH3A/TRAPPC4/CDC42SE2/PARD6B/TBC1D13/SPHK2/TBCK/ARHGDIA/ARHGAP17/TBC1D3C/RAB34/AKAP13/BCR/RIN2/PARD6A/DMXL2/WHAMM/ARHGAP1/MCF2L/C15orf62/WAS/STRN3/NET1/RGPD1/DENND6A/RUSC2/TNPO1/GDI1/SPATA13/PPP6R1/RALBP1/PAK2/ARHGEF26/LSM2	141
MF	GO:0004003	ATP-dependent DNA helicase activity	12/4733	21/17697	0.00313	0.1378	0.1291	MCM5/RAD51/MCM2/PIF1/POLQ/RFC2/MCM7/HELQ/DSCC1/CHTF8/DNA2/HELB	12
MF	GO:0008026	ATP-dependent helicase activity	12/4733	21/17697	0.00313	0.1378	0.1291	MCM5/RAD51/MCM2/PIF1/POLQ/RFC2/MCM7/HELQ/DSCC1/CHTF8/DNA2/HELB	12
MF	GO:0019200	carbohydrate kinase activity	12/4733	21/17697	0.00313	0.1378	0.1291	HK1/PFKFB3/PFKP/HK2/PFKFB4/GNE/GALK2/GALK1/PFKFB2/FGGY/PFKL/NAGK	12
MF	GO:0070035	purine NTP-dependent helicase activity	12/4733	21/17697	0.00313	0.1378	0.1291	MCM5/RAD51/MCM2/PIF1/POLQ/RFC2/MCM7/HELQ/DSCC1/CHTF8/DNA2/HELB	12
MF	GO:0070491	repressing transcription factor binding	30/4733	71/17697	0.003304	0.1403	0.1314	RBBP8/PPARG/BBS2/TLE4/GMNN/HMGB1/SKI/TLE2/STAT3/CBX5/SRI/RBPJ/RUNX2/TCF7L2/TLE3/MKKS/SP1/PARK7/MIER2/DDX20/ARNTL/ZNF703/MTA1/CTBP1/HDAC9/STAT1/MTA3/PPARD/NFYB/MAGEA2B	30
MF	GO:0000287	magnesium ion binding	75/4733	213/17697	0.003834	0.1572	0.1472	MTHFD2/GEM/WNK1/TOP2A/ADPRH/DCTPP1/PPM1N/TREX1/DYRK3/ENO1/CDC42BPG/ATP11A/ATP8B4/MSH6/NCS1/PLK1/FEN1/MAST4/NUDT16/MAP3K6/PKM/PIF1/CDK2/MAPK12/MORC2/PDXP/ICK/HPRT1/HMGCL/NUAK2/EPHX2/IRAK3/EYA2/SIK3/LHPP/MAP3K5/PINK1/DIS3L2/STK3/ENOSF1/CLYBL/MAST2/FIGNL1/PRPSAP2/SNRK/PI4K2A/ENO3/PPA2/ATP10A/PSPH/ATP8B3/BRSK2/IDH3B/NUDT3/ATP10D/ENOPH1/ERN1/ENDOV/XXYLT1/GCLC/TESC/AASDHPPT/PRKACB/STK38/PRPS1/ATP11C/THG1L/PAPOLA/TSSK3/ADPRHL2/ARL3/GSS/YDJC/WRN/FAN1	75
MF	GO:0005200	structural constituent of cytoskeleton	40/4733	102/17697	0.003986	0.158	0.148	TUBB6/PLEC/TUBA1B/PPL/CCDC6/HIP1/TUBA1C/ANK1/ACTG1/TUBB/PLS1/TUBB4B/ADD3/ARPC1B/SPTBN1/YEATS4/TUBE1/TUBB3/SPTAN1/ARPC5/TUBG2/TUBB2A/TUBB4A/INA/VIM/KRT19/VILL/KRT20/BFSP2/KRT31/CD2AP/TUBG1/EPB41/KRT6A/TPM1/NEFL/SORBS3/ADD2/ACTB/TUBGCP3	40
MF	GO:0005085	guanyl-nucleotide exchange factor activity	75/4733	214/17697	0.004383	0.1633	0.1529	RASGRP2/TIAM2/PLEKHG2/ARHGEF39/RINL/ARHGEF40/RASGEF1B/SBF1/ARHGEF18/FGD2/BCAR3/RANGRF/CCZ1/MCF2L2/DOCK8/CYTH2/PSD4/ARHGEF12/ARHGEF5/TIAM1/ARHGEF2/RIC8A/DOCK1/RAPGEF5/EEF1B2/DOCK5/DOCK3/EIF2B3/RABIF/RASGRF2/PREX1/SBF2/PLEKHG1/HPS4/EPS8L2/VAV2/SH3BP5L/PLEKHG7/RALGDS/IQSEC1/SEC61B/RASGRP4/PSD3/RAPGEF1/GBF1/RASGEF1C/SH2D3A/SH2D3C/DENND2D/ECT2/RCC1/RABGEF1/RGL3/TBXA2R/RAPGEF2/ARF4/RALGPS1/OBSCN/DENND3/DOCK9/LAMTOR4/TRAPPC4/CYTH1/LAMTOR2/AKAP13/BCR/RIN2/RIC8B/MCF2L/HERC2/NET1/DENND6A/IQSEC3/SPATA13/ARHGEF26	75
MF	GO:0005041	low-density lipoprotein particle receptor activity	8/4733	12/17697	0.004395	0.1633	0.1529	LRP8/LDLR/SORL1/LRP10/CXCL16/LRP1/LRP12/LRP6	8
MF	GO:0051015	actin filament binding	70/4733	198/17697	0.004552	0.1633	0.1529	MYO7A/FSCN1/ABLIM1/MICAL1/MARCKS/CYFIP1/MYO1E/CORO1C/HIP1/CAPZB/MYH10/GSN/CTTN/SVIL/WIPF2/MYO5C/MYO5A/BLOC1S6/CAPG/CORO1B/PLS1/ADD3/FMNL1/HIP1R/ARPC1B/PICK1/EZR/CORO1A/AIF1/TRIOBP/TWF2/CFL1/ACTN4/COTL1/TPM2/ARPC5/MYBPC3/MYH7B/XIRP2/CAPZA1/MYH7/MAP1S/NRAP/TNNC1/SHROOM1/MYH4/ACTR3B/WDR1/SAMD14/CTNNA1/CORO7/SYNE3/SHROOM3/VILL/MYH9/MYOM1/ABLIM2/UTRN/TPM1/AIF1L/CACNB2/PSTPIP2/PPP1R9B/LASP1/TMEM201/MYH6/WAS/MYBPC2/SYNE2/ADD2	70
MF	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	22/4733	49/17697	0.004669	0.1633	0.1529	CCNF/CDKN1A/CDKN2B/CCNG2/CCNA2/HEXIM1/CCNB2/CDKN2C/CKS2/CCNB1/CKS1B/CCNE2/CCNT2/CDKN2A/CCNK/CCNJ/CCNL2/MNAT1/CCNY/CCNC/CCNI/CCND1	22
MF	GO:0031419	cobalamin binding	7/4733	10/17697	0.00529	0.1747	0.1636	MMAB/TCN1/TCN2/CUBN/MMACHC/MTR/LMBRD1	7
MF	GO:0071723	lipopeptide binding	7/4733	10/17697	0.00529	0.1747	0.1636	CD1E/CD1A/CD1C/CD1B/CD1D/TLR2/TLR6	7
MF	GO:0019205	nucleobase-containing compound kinase activity	20/4733	44/17697	0.005778	0.1808	0.1693	TK1/TJP2/CMPK2/DTYMK/AK5/AK3/NME4/NOL9/NME3/AK4/LRGUK/CARD11/GUK1/AK1/CMPK1/UCK2/N4BP2/NME9/AK2/NME2	20
MF	GO:1901505	carbohydrate derivative transmembrane transporter activity	20/4733	44/17697	0.005778	0.1808	0.1693	SLC29A2/SLC35A2/SLC35E4/SLC29A1/SLC25A23/ABCD1/SLC35B1/SLC25A25/SLC35D2/SLC35D1/SLC35B2/SLC35E3/SLC25A5/SLC35C1/SLC29A3/SLC33A1/SLC25A42/SLC35B4/SLC25A4/SLC28A1	20
MF	GO:0008022	protein C-terminus binding	66/4733	187/17697	0.005993	0.1827	0.1711	CENPF/GPSM2/MKI67/PPARG/TOP2A/CDC20/KSR1/BRCA2/PIAS3/RAD51/SNF8/SRC/SAE1/PRDX3/NUMA1/STIP1/ATF4/TOPBP1/XRCC6/SH3GL1/SYNJ2BP/ATP1B1/SDC1/PICK1/CDK7/ATXN1/PIAS1/EZR/CORO1A/YEATS4/NCL/PPP2CA/BANF1/SP1/SUMO1/YWHAQ/HIC2/ERCC2/KPNA3/ERBB2/PCGF1/VGLL2/YAP1/SDCBP2/NPAT/CD2AP/PIAS4/MDC1/DNM1/MIF4GD/EPB41/CTBP1/MED12/NEIL1/NEFL/EFHC1/ID1/POLR2A/SLC9A3R2/PEX1/SREBF2/ERCC1/MAGI1/DLG4/TERF2/SIRT1	66
MF	GO:0042826	histone deacetylase binding	42/4733	111/17697	0.00678	0.1973	0.1848	TOP2A/SRF/KLF4/RAC1/CDC20/YWHAE/PRDM1/SFPQ/GMNN/KPNA2/ZNHIT1/HSPA1A/SMG5/FOXP3/CBX5/RFXANK/CRY1/UHRF1BP1/KAT2A/BCOR/MEF2D/SP1/MIER2/MEF2B/CEBPB/DDX20/KCTD21/BEX4/SIRT2/BHLHE41/TRAF6/MTA1/HDAC9/MTA3/NR2C1/RARA/CCND1/HDAC10/NCOR1/MAGEA2B/RAD9A/GCM1	42
MF	GO:0004953	icosanoid receptor activity	9/4733	15/17697	0.006802	0.1973	0.1848	PPARG/PTGER4/CYSLTR1/LTB4R/PTGER2/TBXA2R/PTGER1/HPGD/LTB4R2	9
MF	GO:0004721	phosphoprotein phosphatase activity	64/4733	182/17697	0.007365	0.2085	0.1953	PTPN13/DUSP10/DUSP4/CDKN3/PTPRF/PTPN6/DLGAP5/PPM1N/DUSP6/CPPED1/PTPN7/SBF1/CDC25A/MTMR3/PPP2R1A/PPP1CB/PTPN1/CDC25C/PPTC7/PTPN14/DUSP5/PDXP/PALD1/PTPN4/PTPN9/EYA2/LHPP/DUSP16/PTPRC/TIMM50/DUSP23/DUSP22/PPP2CA/PTPN18/PPP1R3E/STYXL1/PPA2/PPP5C/PPM1G/TAB1/DNAJC6/CAMK2G/PTPRM/PHLPP1/PTPMT1/MTMR14/DUSP18/DUPD1/CDC14B/PTPRS/SSH2/ACP1/PPP2R3B/DUSP14/PPP6C/PPM1J/PPM1K/MYH6/PGAM5/CDC25B/PPM1L/PPP1R3B/PTP4A3/DUSP1	64
MF	GO:0019787	ubiquitin-like protein transferase activity	131/4733	407/17697	0.007863	0.2174	0.2037	EGR2/ZNRF1/RNF144A/UBE2C/DTL/UBE2A/RFFL/UHRF1/UBE2S/DDB2/UBE2B/PIAS3/TRIM25/MED20/ASB2/TRAF7/NOSIP/TRIM47/SYVN1/AMN1/TSPAN17/UBE2H/DTX3L/UBE3D/TNFAIP1/TRAIP/FBXL18/TRIM62/UBE2I/TTC3/UBA7/RNF130/RFWD3/NEURL4/MYLIP/HERC3/UBE2N/FBXL14/BCOR/KLHL9/RNF40/FBXO27/UBE4A/SMURF1/UBE2G2/PIAS1/ZNF598/RNF187/ERCC8/TRIM13/KLHL21/DTX4/TRIM23/FBXL8/FEM1B/RNF8/MAEA/PDZRN4/ANAPC11/RNF19B/RNF216/RNF24/RNF213/UBE3A/MGRN1/FBXW11/TOPORS/KIAA1586/HERC2P3/RNF133/PIAS2/LNX1/CUL5/C10orf90/RABGEF1/SIAH2/BIRC3/ANAPC1/RNF7/RLIM/PDZD4/PRPF19/BTRC/TRAF2/HERC6/PIAS4/FBXL4/FBXO11/KCTD13/FBXO9/NEURL2/RNF139/UBR2/LRSAM1/WDSUB1/RNF121/TRAF6/MKRN1/BIRC7/FBXL22/FBXL15/FBXL20/MED12/FBXO44/IRF2BP1/UHRF2/UBE3B/RAG2/HERC2/RNF138/CDC42/ASB1/RNF215/RNF212/HECTD3/UBOX5/ZNF451/FBXO10/UBE2F/FBXO4/RNF148/RNF186/KLHL13/TRIM9/BARD1/RNF168/NHLRC3/UBE2W/PJA2/UBL4A/TRIM5	131
MF	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	8/4733	13/17697	0.008758	0.2323	0.2175	DUSP10/DUSP4/DUSP6/DUSP5/DUSP16/DUSP18/DUSP14/DUSP1	8
MF	GO:0004725	protein tyrosine phosphatase activity	38/4733	100/17697	0.008947	0.2323	0.2175	PTPN13/DUSP10/DUSP4/CDKN3/PTPRF/PTPN6/DUSP6/PTPN7/CDC25A/MTMR3/PTPN1/CDC25C/PTPN14/DUSP5/PALD1/PTPN4/PTPN9/EYA2/DUSP16/PTPRC/TIMM50/DUSP23/DUSP22/PTPN18/DNAJC6/PTPRM/PTPMT1/MTMR14/DUSP18/DUPD1/CDC14B/PTPRS/SSH2/ACP1/DUSP14/CDC25B/PTP4A3/DUSP1	38
MF	GO:0005096	GTPase activator activity	91/4733	273/17697	0.008985	0.2323	0.2175	RGS16/TIAM2/RINL/ARHGAP23/ADPRH/SIPA1L1/RACGAP1/SGSM3/ELMOD1/DEPDC1B/TBC1D9/PLXNB1/SRGAP2/SIPA1L2/RGPD2/ASAP2/ARHGAP9/TBC1D2B/ARHGEF12/ARHGAP11A/ARRB1/RIC8A/DOCK1/ARHGAP31/TBC1D22A/ARHGAP19/DOCK5/ARHGAP35/TBC1D10C/STARD13/ARHGAP5/STXBP5/RASAL2/PREX1/RUNDC1/TBC1D3H/TBC1D20/ARHGAP4/TBC1D10B/RASA3/VPS9D1/TBC1D8/ARAP1/THY1/AGAP5/ADAP2/ARHGAP15/ACAP1/SRGAP3/JUN/ARAP3/RASA4/TBC1D22B/AGAP2/ARHGAP33/ECT2/NUP50/TBC1D2/MYO9B/RGS1/RASAL1/RAPGEF2/CHN1/NPRL3/RAP1GAP2/TBC1D13/GNAQ/TBCK/ARHGAP18/ARHGDIA/ARHGAP17/TBC1D3C/RGS5/BCR/RIN2/ARHGAP24/CHN2/ARHGAP1/DEPDC1/RIC8B/ARHGAP32/ALS2CL/PLCB1/BNIP2/PGAM5/RGPD1/RALGAPA1/GDI1/RALBP1/RGS7/NPRL2	91
MF	GO:0031996	thioesterase binding	7/4733	11/17697	0.0112	0.2774	0.2598	RAC1/TRAF4/TRAF1/TRAF2/TRAF6/ARF6/CDC42	7
MF	GO:0034713	type I transforming growth factor beta receptor binding	7/4733	11/17697	0.0112	0.2774	0.2598	SNX25/SMAD7/TGFB3/SMAD6/FKBP1A/ACVR2B/TGFB1	7
MF	GO:0043531	ADP binding	17/4733	38/17697	0.0127	0.3082	0.2887	MYO7A/ABCG1/MYH10/MSH6/ABCD1/PKM/VCP/CHORDC1/TAP1/PRKAG2/PPP5C/GLUD1/MYO9B/MYH9/ERN1/GCLC/P2RY1	17
MF	GO:0051539	4 iron, 4 sulfur cluster binding	18/4733	41/17697	0.01313	0.3122	0.2925	RSAD2/NUBP1/LIAS/NDUFS1/NDUFS7/POLE/RSAD1/ACO1/ERCC2/TYW1B/DPYD/MOCS1/DDX11/DNA2/ISCU/ISCA2/MUTYH/CDKAL1	18
MF	GO:0003684	damaged DNA binding	26/4733	65/17697	0.01362	0.3127	0.2929	RBBP8/FANCG/TP63/DDB2/HMGB1/MSH6/MPG/NEIL3/FEN1/TP53BP1/POLQ/XRCC6/RPS3/RAD23B/ERCC2/RAD23A/RECQL4/POT1/XRCC1/AUNIP/NEIL1/XPA/OGG1/WRN/MUTYH/ERCC1	26
MF	GO:0005125	cytokine activity	74/4733	220/17697	0.01368	0.3127	0.2929	CXCL13/EBI3/LIF/IL1B/VEGFA/IL18/CSF2/IL21/IL10/CCL20/CCL3L3/TXLNA/IL17A/IL1RN/GRN/CCL22/TNFSF4/CNTF/SPP1/GPI/HMGB1/TNF/CSF1/CXCL10/CMTM7/CCL3/GREM2/TGFB3/CCL2/CCL17/NAMPT/CCL18/CXCL9/CXCL16/SECTM1/IL26/OSM/LTA/CXCL2/WNT7A/GDF7/CXCL3/CMTM2/TIMP1/TNFSF12/IL22/TNFSF9/IL7/IL13/IL20/CMTM8/TNFSF13/LEFTY1/ADIPOQ/IL4/TNFRSF11B/CKLF/TNFSF10/IL36A/FAM3B/BMP10/CCL23/IL17C/BMP3/TNFSF11/CCL7/PPBP/CER1/TGFB1/CCL15/IL32/CCL27/IL37/IL23A	74
MF	GO:0004550	nucleoside diphosphate kinase activity	10/4733	19/17697	0.01454	0.3202	0.2999	CMPK2/DTYMK/AK5/NME4/NME3/AK4/AK1/CMPK1/NME9/NME2	10
MF	GO:0031690	adrenergic receptor binding	10/4733	19/17697	0.01454	0.3202	0.2999	AKAP5/ARRDC3/PDE4D/ARRB1/GNAS/SH3GL1/RAPGEF2/C1QBP/UCHL1/DLG4	10
MF	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	14/4733	30/17697	0.01503	0.3216	0.3012	PHLDA3/SESTD1/HIP1/GAB2/PLEKHA1/DAPP1/MAPKAP1/HIP1R/PLEKHA2/ADAP2/ARAP3/OBSCN/NCF1/RAG2	14
MF	GO:0000295	adenine nucleotide transmembrane transporter activity	8/4733	14/17697	0.01569	0.3216	0.3012	SLC25A23/ABCD1/SLC25A25/SLC35B2/SLC25A5/SLC33A1/SLC25A42/SLC25A4	8
MF	GO:0005338	nucleotide-sugar transmembrane transporter activity	8/4733	14/17697	0.01569	0.3216	0.3012	SLC35A2/SLC35E4/SLC35B1/SLC35D2/SLC35D1/SLC35E3/SLC35C1/SLC35B4	8
MF	GO:0005346	purine ribonucleotide transmembrane transporter activity	8/4733	14/17697	0.01569	0.3216	0.3012	SLC25A23/ABCD1/SLC25A25/SLC35B2/SLC25A5/SLC33A1/SLC25A42/SLC25A4	8
MF	GO:0008094	DNA-dependent ATPase activity	27/4733	69/17697	0.01659	0.3311	0.3101	TOP2A/ERCC6L/MCM5/RAD54L/MSH6/RAD51/MCM2/PIF1/DMC1/POLQ/ZRANB3/RFC2/MCM7/CDK7/SMARCA4/HELQ/DSCC1/CHTF8/ERCC2/GTF2H2/GTF2H1/XRCC3/DDX11/DNA2/MNAT1/HELB/RAD54B	27
MF	GO:0050145	nucleoside monophosphate kinase activity	11/4733	22/17697	0.01671	0.3311	0.3101	TJP2/CMPK2/DTYMK/AK5/AK4/LRGUK/CARD11/GUK1/AK1/CMPK1/AK2	11
MF	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	17/4733	39/17697	0.01701	0.3316	0.3106	PHLDA3/RACGAP1/GAB2/ARHGAP9/DAPP1/MAPKAP1/BTK/HIP1R/NRGN/PIRT/ARAP1/ADAP2/ARAP3/GBF1/PLEKHB2/OBSCN/RAG2	17
MF	GO:0050840	extracellular matrix binding	23/4733	57/17697	0.0175	0.3357	0.3144	VEGFA/ITGA2/ITGA3/GPC1/ANXA2P2/LGALS3/SPP1/ANXA2/NID1/LGALS1/COL11A1/LRRC15/PLEKHA2/SPOCK3/ITGA6/VTN/TGFBI/LACRT/RPSA/ITGA2B/CD248/ADAM9/TINAGL1	23
MF	GO:0048027	mRNA 5'-UTR binding	12/4733	25/17697	0.01843	0.3478	0.3258	MYH10/RPS3A/RPL5/RPL26/MRPS11/RPS13/CCT5/NCL/GNL3/FMR1/UTP23/RARA	12
MF	GO:0055106	ubiquitin-protein transferase regulator activity	9/4733	17/17697	0.01935	0.3544	0.3319	TRIB1/CDC20/RPL5/FBXO5/CBX8/RPL23/RPL11/GLMN/TRIB3	9
MF	GO:0043130	ubiquitin binding	29/4733	76/17697	0.01937	0.3544	0.3319	TOP2A/SQSTM1/TP53INP2/NBR1/CKS2/OTUB2/CKS1B/UBE2N/UBXN1/NPLOC4/TOLLIP/RAD23B/RNF8/RNF19B/MARK4/RAD23A/RAE1/USP5/UCHL3/SIRT2/ZFAND2B/NSFL1C/UBXN11/WDR48/TOM1L1/UCHL1/DNAJB2/NUP62/RNF168	29
MF	GO:0005525	GTP binding	118/4733	374/17697	0.0208	0.358	0.3353	TUBB6/GEM/RAB31/GNA15/RAC1/IRGQ/GBP2/TUBA1B/RAB33A/RABL2A/RTKN/TUBA1C/MX1/LRRK1/SCG5/LANCL2/TUBB/NUDT16/REM1/ARHGEF5/TGM2/RHOG/GPN1/RAB32/EFTUD2/GNAS/RAB13/TUBB4B/GTPBP3/EIF5B/RAB3D/NOA1/ARHGAP35/AK3/ARHGAP5/RAB19/RASD1/REM2/UPRT/TUBE1/GPN2/TUBB3/MRAS/TUBG2/TRIM23/RALA/RASEF/GNL3/NOLC1/GNAI2/RAB27A/EEF1A1/TUBB2A/DRG2/SEPHS1/IFT27/RASD2/RASL11A/TUBB4A/AGAP2/AK4/RAC2/ARL4C/RAB38/MOCS1/GLUD1/EEF1A2/SAMHD1/RHOF/MTG1/GIMAP8/RHOV/ARL16/EIF2S3/ARF4/RHOU/GIMAP2/DAPK1/RAB39B/RAB23/RAB2A/DNM1/RAB40B/TUBG1/RHOT2/RAB40C/GVINP1/DAP3/GNAQ/INSR/RAB15/ARF6/GSPT1/RAB1A/RAB34/LSG1/RAB37/THG1L/RALB/ARL2/ARL3/OLA1/GBP4/RRAGB/EHD3/CDC42/SPAG1/GUF1/GNAT3/TUFM/RAB28/ARL5A/EHD4/RRAS2/RAB1B/RAC3/RAB12/GFM1	118
MF	GO:0140030	modification-dependent protein binding	50/4733	144/17697	0.02085	0.358	0.3353	SQSTM1/PTPN6/PHF19/UHRF1/MSH6/ING1/ING3/ING5/CBX5/TP53BP1/VCP/ZRANB3/UBXN1/PHIP/CBX8/CARM1/TAF1L/SMARCA4/RAD23B/BRD4/CDYL2/CBX2/FAM156B/OTUD7B/KDM8/BRCC3/FMR1/RAD23A/PHF13/BRD9/MBTD1/TNIP3/CDYL/UBQLN2/TAF7/ZFAND2B/MLLT3/KDM5A/PYGO1/BAZ2A/RRP8/UBQLNL/RAG2/FAN1/DNAJB2/PHF8/LRWD1/RNF168/SPIN1/ZFAND6	50
MF	GO:0032550	purine ribonucleoside binding	119/4733	378/17697	0.02172	0.358	0.3353	TUBB6/GEM/RAB31/GNA15/RAC1/IRGQ/GBP2/TUBA1B/RAB33A/RABL2A/RTKN/TUBA1C/MX1/LRRK1/SCG5/LANCL2/TUBB/NUDT16/REM1/ARHGEF5/TGM2/RHOG/GPN1/RAB32/EFTUD2/GNAS/RAB13/TUBB4B/GTPBP3/EIF5B/RAB3D/NOA1/ARHGAP35/AK3/ARHGAP5/RAB19/RASD1/REM2/UPRT/TUBE1/GPN2/TUBB3/MRAS/TUBG2/TRIM23/RALA/RASEF/GNL3/NOLC1/GNAI2/RAB27A/EEF1A1/TUBB2A/DRG2/SEPHS1/IFT27/RASD2/RASL11A/TUBB4A/AGAP2/AK4/RAC2/ARL4C/RAB38/MOCS1/GLUD1/EEF1A2/SAMHD1/RHOF/MTG1/GIMAP8/RHOV/ARL16/EIF2S3/ARF4/RHOU/GIMAP2/DAPK1/RAB39B/RAB23/RAB2A/DNM1/RAB40B/TUBG1/RHOT2/RAB40C/GVINP1/DAP3/GNAQ/INSR/RAB15/ARF6/GSPT1/RAB1A/RAB34/LSG1/RAB37/THG1L/RALB/ARL2/ARL3/OLA1/GBP4/RRAGB/EHD3/CDC42/SPAG1/GUF1/GNAT3/TUFM/RAB28/ARL5A/EHD4/RRAS2/NME2/RAB1B/RAC3/RAB12/GFM1	119
MF	GO:0042162	telomeric DNA binding	16/4733	37/17697	0.02204	0.358	0.3353	SMG5/TP53BP1/PIF1/XRCC6/UPF1/TERF1/NCL/ACD/CTC1/POT1/UPF3A/SMG6/TINF2/WRN/ZBTB48/TERF2	16
MF	GO:0001047	core promoter binding	22/4733	55/17697	0.02212	0.358	0.3353	GADD45A/UBTF/ZBTB17/SMARCB1/MMP12/NR3C1/POU2F1/ELK4/SMARCA4/EZH2/ZNF507/SOX8/ZNF827/CEBPB/KLF10/ZNF407/BAZ2A/STAT1/POU2AF1/POGZ/FOS/ZNF451	22
MF	GO:0043138	3'-5' DNA helicase activity	10/4733	20/17697	0.02222	0.358	0.3353	MCM5/MCM2/CDC45/GINS2/GINS1/GINS4/MCM7/RECQL5/RECQL4/WRN	10
MF	GO:0004842	ubiquitin-protein transferase activity	120/4733	382/17697	0.02267	0.358	0.3353	ZNRF1/RNF144A/UBE2C/DTL/UBE2A/RFFL/UHRF1/UBE2S/DDB2/UBE2B/TRIM25/MED20/ASB2/TRAF7/NOSIP/TRIM47/SYVN1/AMN1/TSPAN17/UBE2H/DTX3L/UBE3D/TNFAIP1/TRAIP/FBXL18/TRIM62/TTC3/UBA7/RNF130/RFWD3/NEURL4/MYLIP/HERC3/UBE2N/FBXL14/BCOR/KLHL9/RNF40/FBXO27/UBE4A/SMURF1/UBE2G2/ZNF598/RNF187/ERCC8/TRIM13/KLHL21/DTX4/TRIM23/FBXL8/FEM1B/RNF8/MAEA/PDZRN4/ANAPC11/RNF19B/RNF216/RNF24/RNF213/UBE3A/MGRN1/FBXW11/TOPORS/HERC2P3/RNF133/LNX1/CUL5/C10orf90/RABGEF1/SIAH2/BIRC3/ANAPC1/RNF7/RLIM/PDZD4/PRPF19/BTRC/TRAF2/HERC6/FBXL4/FBXO11/KCTD13/FBXO9/NEURL2/RNF139/UBR2/LRSAM1/WDSUB1/RNF121/TRAF6/MKRN1/BIRC7/FBXL22/FBXL15/FBXL20/MED12/FBXO44/IRF2BP1/UHRF2/UBE3B/RAG2/HERC2/RNF138/CDC42/ASB1/RNF215/HECTD3/UBOX5/FBXO10/FBXO4/RNF148/RNF186/KLHL13/TRIM9/BARD1/RNF168/NHLRC3/UBE2W/PJA2/TRIM5	120
MF	GO:0032549	ribonucleoside binding	120/4733	382/17697	0.02267	0.358	0.3353	TUBB6/GEM/RAB31/GNA15/RAC1/IRGQ/GBP2/TUBA1B/RAB33A/RABL2A/RTKN/TUBA1C/MX1/LRRK1/SCG5/LANCL2/TUBB/NUDT16/REM1/ARHGEF5/TGM2/RHOG/GPN1/RAB32/EFTUD2/GNAS/RAB13/TUBB4B/GTPBP3/EIF5B/RAB3D/NOA1/ARHGAP35/AK3/ARHGAP5/RAB19/RASD1/REM2/UPRT/TUBE1/GPN2/TUBB3/MRAS/TUBG2/TRIM23/RALA/RASEF/GNL3/NOLC1/GNAI2/RAB27A/EEF1A1/TUBB2A/DRG2/SEPHS1/IFT27/RASD2/RASL11A/TUBB4A/AGAP2/AK4/RAC2/ARL4C/RAB38/MOCS1/GLUD1/EEF1A2/SAMHD1/RHOF/MTG1/GIMAP8/RHOV/ARL16/EIF2S3/ARF4/RHOU/GIMAP2/DAPK1/RAB39B/RAB23/RAB2A/DNM1/RAB40B/TUBG1/RHOT2/RAB40C/GVINP1/DAP3/GNAQ/INSR/RAB15/ARF6/GSPT1/RAB1A/RAB34/LSG1/RAB37/THG1L/RALB/ARL2/ARL3/OLA1/GBP4/RRAGB/EHD3/CDC42/SPAG1/GUF1/GNAT3/TUFM/POLR1B/RAB28/ARL5A/EHD4/RRAS2/NME2/RAB1B/RAC3/RAB12/GFM1	120
MF	GO:0001882	nucleoside binding	122/4733	389/17697	0.02282	0.358	0.3353	TUBB6/GEM/RAB31/GNA15/RAC1/IRGQ/GBP2/TUBA1B/RAB33A/RABL2A/RTKN/TUBA1C/MX1/LRRK1/SCG5/LANCL2/TUBB/NUDT16/REM1/ARHGEF5/TGM2/RHOG/GPN1/RAB32/EFTUD2/GNAS/RAB13/TUBB4B/GTPBP3/EIF5B/RAB3D/NOA1/ARHGAP35/AK3/PNP/ARHGAP5/RAB19/RASD1/REM2/UPRT/TUBE1/ACTN4/GPN2/TUBB3/MRAS/TUBG2/TRIM23/RALA/RASEF/GNL3/NOLC1/GNAI2/RAB27A/EEF1A1/TUBB2A/DRG2/SEPHS1/IFT27/RASD2/RASL11A/TUBB4A/AGAP2/AK4/RAC2/ARL4C/RAB38/MOCS1/GLUD1/EEF1A2/SAMHD1/RHOF/MTG1/GIMAP8/RHOV/ARL16/EIF2S3/ARF4/RHOU/GIMAP2/DAPK1/RAB39B/RAB23/RAB2A/DNM1/RAB40B/TUBG1/RHOT2/RAB40C/GVINP1/DAP3/GNAQ/INSR/RAB15/ARF6/GSPT1/RAB1A/RAB34/LSG1/RAB37/THG1L/RALB/ARL2/ARL3/OLA1/GBP4/RRAGB/EHD3/CDC42/SPAG1/GUF1/GNAT3/TUFM/POLR1B/RAB28/ARL5A/EHD4/RRAS2/NME2/RAB1B/RAC3/RAB12/GFM1	122
MF	GO:0032182	ubiquitin-like protein binding	35/4733	96/17697	0.02306	0.358	0.3353	TOP2A/SQSTM1/TP53INP2/PML/SERBP1/NBR1/NR3C1/CKS2/OTUB2/CKS1B/UBE2N/UBXN1/NPLOC4/TOLLIP/RAD23B/RNF8/CASP8AP2/RNF19B/MARK4/RAD23A/RAE1/USP5/UCHL3/DCUN1D4/SIRT2/ZFAND2B/NSFL1C/UBXN11/WDR48/HERC2/TOM1L1/UCHL1/DNAJB2/NUP62/RNF168	35
MF	GO:0005126	cytokine receptor binding	92/4733	286/17697	0.02309	0.358	0.3353	CXCL13/EBI3/LIF/IL1B/VEGFA/IL18/CSF2/IL21/IL10/CCL20/NTRK1/CCL3L3/LRG1/IL1RN/SPRED2/CCL22/TNFSF4/CNTF/SNX25/CCRL2/SOCS2/TNF/CSF1/NOL3/CXCL10/STAT3/SMAD7/CCR2/CFLAR/TRIP6/CCL3/SDCBP/TGFB3/SMAD6/CCL2/TOLLIP/PDCL3/CCL17/BID/CD300LF/TIMM50/CCL18/CXCL9/CXCL16/TRAF4/IL12RB1/FKBP1A/FEM1B/OSM/LTA/CXCL2/CASP8AP2/GDF7/CXCL3/ACVR2B/TNFSF12/TRAF1/PIBF1/IL22/TNFSF9/IL7/ERAP1/IL13/IL20/TRAF2/CD2AP/TNFSF13/LEFTY1/IL4/CKLF/TNFSF10/IL36A/BMP10/TRAF6/CCL23/BMP3/STAT1/TNFSF11/CCL7/NTF3/PPBP/DDT/TGFB1/CCL15/CDH5/GATA3/SHC1/CCL27/VEGFC/IL37/JAK1/IL23A	92
MF	GO:0045296	cadherin binding	105/4733	331/17697	0.02401	0.358	0.3353	PLEC/ANLN/FSCN1/LDHA/CCNB2/ENO1/PFKP/PPL/YWHAE/YWHAZ/SERBP1/SNX9/CHMP2B/CAPZB/HSPA5/PDXDC1/HSPA1A/CTTN/PTPN1/TJP2/TRIM25/ANXA2/CLIC1/PLIN3/RPL23A/CDC42EP1/SWAP70/STX5/SRC/CAPG/SFN/PKM/CORO1B/PAK4/AHSA1/LRRC59/RPL6/SLC3A2/MPP7/SH3GL1/MICALL1/EPS8L2/SPTBN1/EZR/NDRG1/VASP/TWF2/ITGA6/DIAPH3/PKP4/SPTAN1/SCRIB/EIF4H/RPL14/VASN/CAPZA1/CD46/PARK7/EMD/UBFD1/S100A11/FXYD5/RPL29/PTPRM/CDH26/TMPO/MMP24/CDH9/IST1/TBC1D2/BAG3/BSG/CTNNA1/EIF2S3/PRDX6/CD2AP/ALDOA/GIGYF2/MYH9/ZC3HAV1/RPL7A/DOCK9/ARVCF/CNN2/STK38/FASN/AHNAK/ARHGAP18/RAB1A/STAT1/CLINT1/CCS/EIF3E/WASF2/LASP1/ARHGAP1/OLA1/LAD1/SLC9A3R2/CDH5/PRDX1/CKAP5/EHD4/PAK2/USO1	105
MF	GO:0019902	phosphatase binding	62/4733	185/17697	0.02419	0.358	0.3353	PPARG/WNK1/MVP/CSF1R/NEK2/SIRPA/LGALS3/CEACAM1/MTMR3/STRN4/EIF4EBP1/AKAP5/ANK1/PTPN1/SMG5/STAT3/PDLIM4/SH2D4A/VCP/PPP1R18/CD33/CRY1/SH3YL1/KAT2A/BOD1/SH3GL1/FOXO1/SBF2/MAP3K5/MTMR9/ITGA1/SFI1/KCNN4/MAST2/LILRB2/ATP2B4/PPP1R32/STYXL1/ERBB2/CEP192/FLT4/TRAF2/EIF2AK3/CDC5L/FER/ELL/STAU1/SIGLEC10/PPP1R15A/STAT1/PPP1R9B/SIGLEC11/CNST/STRN3/JAK3/MAPK1/SLC9A3R2/CDH5/PPP6R1/BAD/DLG4/JAK1	62
MF	GO:0044183	protein binding involved in protein folding	11/4733	23/17697	0.02442	0.358	0.3353	HSPA2/HSPA5/HSPA1A/PFDN2/HSPA9/CD74/RIC3/PDCL3/HSPA6/HSPA1L/HSPA14	11
MF	GO:0035064	methylated histone binding	25/4733	65/17697	0.0258	0.358	0.3353	PHF19/UHRF1/MSH6/ING1/ING3/ING5/CBX5/TP53BP1/CBX8/CDYL2/CBX2/FAM156B/KDM8/FMR1/PHF13/MBTD1/CDYL/TAF7/KDM5A/PYGO1/RRP8/RAG2/PHF8/LRWD1/SPIN1	25
MF	GO:0140034	methylation-dependent protein binding	25/4733	65/17697	0.0258	0.358	0.3353	PHF19/UHRF1/MSH6/ING1/ING3/ING5/CBX5/TP53BP1/CBX8/CDYL2/CBX2/FAM156B/KDM8/FMR1/PHF13/MBTD1/CDYL/TAF7/KDM5A/PYGO1/RRP8/RAG2/PHF8/LRWD1/SPIN1	25
MF	GO:0015216	purine nucleotide transmembrane transporter activity	8/4733	15/17697	0.02584	0.358	0.3353	SLC25A23/ABCD1/SLC25A25/SLC35B2/SLC25A5/SLC33A1/SLC25A42/SLC25A4	8
MF	GO:0033549	MAP kinase phosphatase activity	8/4733	15/17697	0.02584	0.358	0.3353	DUSP10/DUSP4/DUSP6/DUSP5/DUSP16/DUSP18/DUSP14/DUSP1	8
MF	GO:0035925	mRNA 3'-UTR AU-rich region binding	12/4733	26/17697	0.02606	0.358	0.3353	ZFP36/HNRNPA0/ZFP36L2/MEX3D/ZC3H12A/ELAVL1/ILF3/CPSF1/ZFP36L1/CPEB1/KHSRP/EXOSC9	12
MF	GO:0043015	gamma-tubulin binding	12/4733	26/17697	0.02606	0.358	0.3353	RACGAP1/BRCA2/B9D2/PDE4B/TUBGCP2/CEP70/NDRG1/MARK4/NDN/RAB11FIP5/TUBGCP5/TUBGCP3	12
MF	GO:0003697	single-stranded DNA binding	40/4733	113/17697	0.02629	0.358	0.3353	RBBP8/TOP3A/MCM4/TREX1/MCM5/MCM10/HMGB1/BRCA2/NEIL3/RAD51/RAD51AP1/MCM2/CDC45/DMC1/SSBP3/MCM7/TERF1/RAD23B/SSBP2/CNBP/CTC1/ERCC5/MCM3/RAD23A/TSNAX/SAMHD1/POT1/DDX11/LRPPRC/SSBP1/PURB/YBX1/RAD52/NUP35/NUCKS1/RNF138/POU4F1/ERCC1/TERF2/TSN	40
MF	GO:0035035	histone acetyltransferase binding	13/4733	29/17697	0.02724	0.358	0.3353	EGR1/NR4A3/FOXP3/KANSL1L/TRIP4/SP1/EPAS1/CITED2/CEBPB/SIRT2/TAF7/STAT1/BCAS3	13
MF	GO:0043236	laminin binding	13/4733	29/17697	0.02724	0.358	0.3353	ITGA2/ITGA3/GPC1/LGALS3/NID1/LGALS1/LRRC15/PLEKHA2/ITGA6/LACRT/RPSA/ADAM9/TINAGL1	13
MF	GO:0071889	14-3-3 protein binding	13/4733	29/17697	0.02724	0.358	0.3353	KSR1/ZFP36/TBC1D22A/DDIT4/YWHAQ/TBC1D22B/PRKCE/NEK1/AANAT/ZFP36L1/KLHL22/PPP1R12A/BAD	13
MF	GO:0001883	purine nucleoside binding	119/4733	381/17697	0.02738	0.358	0.3353	TUBB6/GEM/RAB31/GNA15/RAC1/IRGQ/GBP2/TUBA1B/RAB33A/RABL2A/RTKN/TUBA1C/MX1/LRRK1/SCG5/LANCL2/TUBB/NUDT16/REM1/ARHGEF5/TGM2/RHOG/GPN1/RAB32/EFTUD2/GNAS/RAB13/TUBB4B/GTPBP3/EIF5B/RAB3D/NOA1/ARHGAP35/AK3/ARHGAP5/RAB19/RASD1/REM2/UPRT/TUBE1/GPN2/TUBB3/MRAS/TUBG2/TRIM23/RALA/RASEF/GNL3/NOLC1/GNAI2/RAB27A/EEF1A1/TUBB2A/DRG2/SEPHS1/IFT27/RASD2/RASL11A/TUBB4A/AGAP2/AK4/RAC2/ARL4C/RAB38/MOCS1/GLUD1/EEF1A2/SAMHD1/RHOF/MTG1/GIMAP8/RHOV/ARL16/EIF2S3/ARF4/RHOU/GIMAP2/DAPK1/RAB39B/RAB23/RAB2A/DNM1/RAB40B/TUBG1/RHOT2/RAB40C/GVINP1/DAP3/GNAQ/INSR/RAB15/ARF6/GSPT1/RAB1A/RAB34/LSG1/RAB37/THG1L/RALB/ARL2/ARL3/OLA1/GBP4/RRAGB/EHD3/CDC42/SPAG1/GUF1/GNAT3/TUFM/RAB28/ARL5A/EHD4/RRAS2/NME2/RAB1B/RAC3/RAB12/GFM1	119
MF	GO:0140078	class I DNA-(apurinic or apyrimidinic site) endonuclease activity	6/4733	10/17697	0.0274	0.358	0.3353	APEX2/NEIL3/RPS3/APLF/NEIL1/OGG1	6
MF	GO:0019956	chemokine binding	14/4733	32/17697	0.02806	0.3626	0.3396	CXCR6/CCR1/CCRL2/PLP2/HMGB1/ZFP36/CCR6/CCR2/CCR4/CCR5/A2M/CCR8/CXCR5/CX3CR1	14
MF	GO:0030674	protein binding, bridging	57/4733	170/17697	0.02936	0.3752	0.3515	FSCN1/GAS2L1/SH2B2/BCL3/TIRAP/SLA/HIP1/SOCS2/SH2D2A/ANK1/SPSB1/TJP2/DET1/GAB2/CUX1/CLNK/FRMD4A/SRC/CBX5/ARRB1/SH2D1A/SDCBP/STAM/COL8A2/HERPUD1/GRAP2/HIP1R/TRIM22/COL11A1/ARHGAP4/LAT/ARRDC4/AP2S1/SLA2/SUMO1/ADAP2/ERCC2/SH2D3A/CRK/SH2D3C/DDX20/SPSB2/CHN1/PEX3/CDYL/ACTR1A/DOK2/LDLRAP1/ARRDC1/MAP1A/NEFL/CHN2/LASP1/ARHGAP1/TCAP/SHC1/TRIM5	57
MF	GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	9/4733	18/17697	0.02967	0.3752	0.3515	CDK1/CDK7/BRD4/ERCC2/CCNK/GTF2H2/GTF2H1/MNAT1/MAPK1	9
MF	GO:0044325	ion channel binding	43/4733	124/17697	0.03099	0.3855	0.3611	RIMS3/YWHAH/YWHAE/CHERP/YWHAZ/ANK1/RANGRF/TSPO/RNF207/SRC/SCN1B/HOMER1/PDE4D/ARRB1/KCNE3/PDE4B/SRI/HERPUD1/PKD2/HTT/SH3GL1/CASR/FGF13/ACTN4/S100A10/BAK1/PIRT/FKBP1A/STAC/YWHAQ/VDAC1/PRKCSH/FMR1/BAG2/CAMK2D/KCNE4/PRNP/KCND3/GOPC/ANKRD9/TCAP/CDH5/FYN	43
MF	GO:0035091	phosphatidylinositol binding	79/4733	245/17697	0.03137	0.3855	0.3611	SNX8/PHLDA3/FES/TIRAP/SESTD1/NCF4/RACGAP1/SNX25/ANXA2P2/MYO1E/HIP1/SNX9/FGD2/PLEKHN1/GAB2/ANXA2/ARHGAP9/LANCL2/PITPNA/PLEKHA1/DAPP1/NUMA1/MAPKAP1/BTK/PIGK/SDCBP/ATP13A2/C2CD2L/PXDC1/SH3YL1/KCNJ2/ZFYVE9/PFN2/HIP1R/NRGN/PITPNM1/CEACAM5/GSDMC/SBF2/TPCN1/PLEKHA2/TWF2/PIRT/ARAP1/THY1/ADAP2/ARAP3/GBF1/SH3PXD2B/SNX11/SNX19/PLEKHA8/ARHGAP33/SNX33/SNX12/SAP30L/SDCBP2/SNX15/PLEKHB2/KRIT1/EEA1/OBSCN/CLVS1/LDLRAP1/RPH3A/EPB41/WDR45/AIDA/GSDMA/TNFAIP8L3/NCF1/GSDMB/MITD1/MCF2L/ARHGAP32/RAG2/PLCB1/PLEKHA3/ZCCHC14	79
MF	GO:0004713	protein tyrosine kinase activity	46/4733	134/17697	0.03145	0.3855	0.3611	TTK/TYRO3/NTRK2/CSF1R/FES/NTRK1/MELK/HCK/EPHB1/DYRK3/SLA/BLK/SRC/EPHB4/MERTK/MAP2K3/BTK/NTRK3/AXL/IGF1R/MAP2K6/FLT3/STK16/PTK6/DYRK4/TXK/FLT1/INSRR/CRIM1/ERBB2/DDR1/NEK1/ITK/MAP2K4/FLT4/CLK3/LTK/RIPK2/FER/INSR/TIE1/CLK2/JAK3/ZAP70/FYN/JAK1	46
MF	GO:0017049	GTP-Rho binding	10/4733	21/17697	0.03245	0.3898	0.3651	CDC42EP4/ANLN/RTKN/CDC42EP1/TNFAIP1/WHAMMP3/TRIOBP/KCTD13/WHAMM/C15orf62	10
MF	GO:0019789	SUMO transferase activity	10/4733	21/17697	0.03245	0.3898	0.3651	EGR2/PIAS3/UBE2I/PIAS1/TOPORS/KIAA1586/PIAS2/PIAS4/RNF212/ZNF451	10
MF	GO:0019955	cytokine binding	44/4733	128/17697	0.03398	0.4004	0.375	EBI3/CD109/IL18BP/CSF1R/IL1R1/CXCR6/IL1RN/CSF3R/CCR1/CCRL2/PLP2/HMGB1/ZFP36/IL2RA/IL2RB/IL1R2/CCR6/CCR2/CCR4/IL2RG/GREM2/IL12RB2/TGFB3/CD74/CCR5/A2M/CSF2RA/IL12RB1/IL27RA/VASN/IL18R1/PARK7/IL5RA/CCR8/IL11RA/IFNGR1/TNFRSF1B/IL10RA/CER1/TCAP/CXCR5/TRIM16/CX3CR1/LRRC32	44
MF	GO:0003688	DNA replication origin binding	11/4733	24/17697	0.03442	0.4004	0.375	MCM4/MCM5/CDC6/MCM10/MCM2/CDC45/ORC1/MCM7/MCM3/DDX11/ORC2	11
MF	GO:0019957	C-C chemokine binding	11/4733	24/17697	0.03442	0.4004	0.375	CXCR6/CCR1/CCRL2/ZFP36/CCR6/CCR2/CCR4/CCR5/CCR8/CXCR5/CX3CR1	11
MF	GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	7/4733	13/17697	0.03468	0.4004	0.375	NDOR1/CYB5R2/NQO1/MTRR/CYB5R1/POR/CYB5RL	7
MF	GO:0001046	core promoter sequence-specific DNA binding	18/4733	45/17697	0.03635	0.4116	0.3855	GADD45A/UBTF/SMARCB1/POU2F1/SMARCA4/EZH2/ZNF507/SOX8/ZNF827/CEBPB/KLF10/ZNF407/BAZ2A/STAT1/POU2AF1/POGZ/FOS/ZNF451	18
MF	GO:0008138	protein tyrosine/serine/threonine phosphatase activity	18/4733	45/17697	0.03635	0.4116	0.3855	DUSP10/DUSP4/CDKN3/DUSP6/SBF1/DUSP5/DUSP16/DUSP23/DUSP22/STYXL1/PTPMT1/DUSP18/DUPD1/CDC14B/SSH2/DUSP14/PTP4A3/DUSP1	18
MF	GO:0005543	phospholipid binding	131/4733	427/17697	0.03696	0.4145	0.3883	SNX8/ABCG1/PHLDA3/FES/CPNE7/TIRAP/SESTD1/NCF4/RACGAP1/SNX25/ANXA2P2/MYO1E/PCTP/HIP1/SNX9/HMGB1/FGD2/PLEKHN1/MAP1LC3A/GAB2/ANXA2/ARHGAP9/LANCL2/PITPNA/PLEKHA1/PSD4/DAPP1/NUMA1/SYT4/MAPKAP1/BTK/PIGK/SDCBP/ATP13A2/C2CD2L/AXL/PXDC1/MYOF/SH3YL1/KCNJ2/CPNE5/ZFYVE9/PFN2/HIP1R/NRGN/PITPNM1/ARHGAP35/CEACAM5/MICALL1/JAG1/GSDMC/NME4/PREX1/SBF2/SMURF1/PICK1/TPCN1/GRAMD1B/SPTBN1/CD300LF/ANXA9/PLEKHA2/ANXA5/PRKCI/TWF2/ABCA1/PIRT/ARAP1/THY1/ADAP2/ARAP3/GBF1/GPR12/RASA4/SH3PXD2B/SNX11/SNX19/ANXA4/PLEKHA8/SYT11/ARHGAP33/SNX33/SNX12/SAP30L/SDCBP2/PLA2G15/RASAL1/RAPGEF2/SNX15/PLEKHB2/F3/KRIT1/PLA2G2A/EEA1/OBSCN/NSFL1C/PLA2G2C/CLVS1/SYTL3/LDLRAP1/RPH3A/EPB41/DOC2B/GRK5/WDR45/AIDA/PACSIN1/GLE1/CHMP2A/CETP/GSDMA/TNFAIP8L3/GLTPD2/NCF1/CPNE4/NUP35/PLA2G5/GSDMB/MITD1/MCF2L/ARHGAP32/RAG2/PLCB1/SYT15/PLEKHA3/NUP62/PTAFR/SHC1/ZCCHC14/CHMP3/BAD	131
MF	GO:0031072	heat shock protein binding	41/4733	119/17697	0.03819	0.4244	0.3975	CDK1/HSPA2/CDK5/DNAJA1/KSR1/HSPA5/ZFP36/HSPA1A/BAX/NR3C1/RNF207/HSPA9/STIP1/AHSA1/DNAJB12/PDXP/USP19/RPS3/HTT/BCOR/DNAJA3/FKBP5/CHORDC1/BAK1/NOD2/IRAK1/LIMK1/PPP5C/ARNTL/LMAN2/FICD/HSPA6/BAG2/DNAJB6/EIF2AK3/ERN1/HSPA1L/HSPA14/CAMKMT/DNAJB2/NUP62	41
MF	GO:0022841	potassium ion leak channel activity	8/4733	16/17697	0.03979	0.4301	0.4029	KCNK5/KCNK6/KCNK7/KCNK1/TMEM175/KCNK15/KCNK18/KCNK2	8
MF	GO:0023026	MHC class II protein complex binding	8/4733	16/17697	0.03979	0.4301	0.4029	YWHAE/HLA-DMA/PKM/CD74/ATP1B1/HLA-DRA/HLA-DMB/HLA-DRB1	8
MF	GO:0071617	lysophospholipid acyltransferase activity	8/4733	16/17697	0.03979	0.4301	0.4029	MBOAT7/AGPAT3/AGPAT2/LPCAT2/LPCAT4/LCLAT1/TAZ/CRLS1	8
MF	GO:0005086	ARF guanyl-nucleotide exchange factor activity	9/4733	19/17697	0.04328	0.439	0.4112	CYTH2/PSD4/IQSEC1/SEC61B/PSD3/GBF1/ARF4/CYTH1/IQSEC3	9
MF	GO:0015215	nucleotide transmembrane transporter activity	9/4733	19/17697	0.04328	0.439	0.4112	SLC25A23/ABCD1/SLC25A25/SLC35B2/SLC25A5/SLC25A36/SLC33A1/SLC25A42/SLC25A4	9
MF	GO:0016722	oxidoreductase activity, oxidizing metal ions	9/4733	19/17697	0.04328	0.439	0.4112	STEAP3/FXN/HEPH/FTL/MMACHC/MTRR/FRRS1/FTH1/CYBRD1	9
MF	GO:0070300	phosphatidic acid binding	9/4733	19/17697	0.04328	0.439	0.4112	SESTD1/PLEKHN1/MAPKAP1/ATP13A2/NRGN/PITPNM1/MICALL1/GRAMD1B/RAPGEF2	9
MF	GO:0008009	chemokine activity	19/4733	49/17697	0.04421	0.439	0.4112	CXCL13/CCL20/CCL3L3/CCL22/CXCL10/CCL3/CCL2/CCL17/CCL18/CXCL9/CXCL16/CXCL2/CXCL3/CKLF/CCL23/CCL7/PPBP/CCL15/CCL27	19
MF	GO:0032813	tumor necrosis factor receptor superfamily binding	18/4733	46/17697	0.0452	0.439	0.4112	TNFSF4/TNF/NOL3/CFLAR/BID/TRAF4/FEM1B/LTA/CASP8AP2/TNFSF12/TRAF1/TNFSF9/TRAF2/TNFSF13/TNFSF10/TRAF6/STAT1/TNFSF11	18
MF	GO:0019838	growth factor binding	46/4733	137/17697	0.04533	0.439	0.4112	CXCL13/FURIN/CD109/NTRK2/IL1R1/NTRK1/COL5A1/PDGFA/IGFBP4/IL1RN/CSF3R/GPC1/IL2RA/S100A13/IL2RB/IL1R2/IL2RG/NTRK3/IGF1R/TGFB3/COL6A1/IGFBP3/RPS19/ITGA6/A2M/SEC61B/FLT1/VASN/CRIM1/ACVR1C/ACVR2B/ERBB2/IL11RA/FIBP/FLT4/HTRA4/FGFBP2/INSR/IL10RA/HTRA1/PDGFB/TRIM16/SHC1/IGFBP6/LRRC32/DUSP1	46
MF	GO:0004519	endonuclease activity	43/4733	127/17697	0.04538	0.439	0.4112	ZC3H12C/RBBP8/EXO1/APEX2/ZC3H12D/FEN1/TSEN2/NUDT16/RNASE8/PELO/TSEN15/RPS3/ZRANB3/POP5/RNASEH2A/TSEN34/ELAC1/ENDOD1/ERCC5/YBEY/RNASE6/DNASE1L2/APLF/TSNAX/ZC3H12A/XRCC3/XRCC1/EME1/PPP1R8/DNA2/ERN1/ENDOV/SMG6/DICER1/N4BP2/RPP30/ZC3H12B/RCL1/OGG1/FAN1/DIS3L/ERCC1/TSN	43
MF	GO:0030742	GTP-dependent protein binding	10/4733	22/17697	0.04558	0.439	0.4112	RAB32/RAPGEF5/RAB3D/MRAS/GCHFR/RASGRP4/RAB38/EEA1/RAB34/PARD6A	10
MF	GO:0048020	CCR chemokine receptor binding	17/4733	43/17697	0.04609	0.439	0.4112	CXCL13/CCL20/CCL3L3/CCL22/CCRL2/STAT3/CCR2/CCL3/CCL2/CCL17/CCL18/CCL23/STAT1/CCL7/CCL15/CCL27/JAK1	17
MF	GO:0004954	prostanoid receptor activity	6/4733	11/17697	0.04683	0.439	0.4112	PPARG/PTGER4/PTGER2/TBXA2R/PTGER1/HPGD	6
MF	GO:0070411	I-SMAD binding	6/4733	11/17697	0.04683	0.439	0.4112	TGFB1I1/SMAD7/SMAD6/SMURF1/SMAD1/AXIN2	6
MF	GO:0008139	nuclear localization sequence binding	11/4733	25/17697	0.04699	0.439	0.4112	KPNA2/NUP98/NUP153/NOLC1/RANBP6/KPNA3/NFKBIA/CABP1/POM121C/POM121L2/TNPO1	11
MF	GO:0035586	purinergic receptor activity	11/4733	25/17697	0.04699	0.439	0.4112	ADORA2A/P2RY13/P2RX1/P2RY11/GPR34/P2RX6/P2RY10/P2RX5/P2RY1/PTAFR/P2RX7	11
MF	GO:0017147	Wnt-protein binding	15/4733	37/17697	0.04748	0.439	0.4112	TYRO3/MERTK/CTHRC1/AXL/SFRP4/FZD6/FZD8/RECK/LRP5L/SFRP1/FZD9/LRP6/FZD5/PORCN/TRABD2B	15
MF	GO:0051393	alpha-actinin binding	15/4733	37/17697	0.04748	0.439	0.4112	PPARG/ADORA2A/PDLIM4/MYOT/PKD2/PDLIM7/MYBPC3/XIRP2/NRAP/C10orf90/ALMS1/MYOM1/MYBPC2/RARA/MAGI1	15
MF	GO:0017091	AU-rich element binding	12/4733	28/17697	0.04774	0.439	0.4112	ZFP36/HNRNPA0/ZFP36L2/MEX3D/ZC3H12A/ELAVL1/ILF3/CPSF1/ZFP36L1/CPEB1/KHSRP/EXOSC9	12
MF	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	12/4733	28/17697	0.04774	0.439	0.4112	PHLDA3/SESTD1/HIP1/MAPKAP1/ATP13A2/HIP1R/TPCN1/GBF1/SH3PXD2B/CLVS1/WDR45/RAG2	12
MF	GO:0005164	tumor necrosis factor receptor binding	13/4733	31/17697	0.048	0.439	0.4112	TNFSF4/TNF/TRAF4/LTA/TNFSF12/TRAF1/TNFSF9/TRAF2/TNFSF13/TNFSF10/TRAF6/STAT1/TNFSF11	13
MF	GO:0015175	neutral amino acid transmembrane transporter activity	13/4733	31/17697	0.048	0.439	0.4112	SLC1A5/SLC1A1/SLC7A5/SFXN1/SLC36A1/SLC43A1/SLC1A4/SLC3A2/SLC38A9/SLC38A2/SLC36A4/SLC6A20/SFXN3	13
MF	GO:0004536	deoxyribonuclease activity	22/4733	59/17697	0.04929	0.4473	0.419	RBBP8/EXO1/TREX1/APEX2/FEN1/RPS3/ZRANB3/ISG20/ERCC5/POLE/DNASE1L2/APLF/DFFB/XRCC3/XRCC1/EME1/DNA2/ENDOV/DICER1/FAN1/ERCC1/RAD9A	22
MF	GO:0061659	ubiquitin-like protein ligase activity	73/4733	230/17697	0.05153	0.4625	0.4332	EGR2/ZNRF1/RNF144A/RFFL/UHRF1/PIAS3/TRIM25/MED20/ASB2/NOSIP/SYVN1/UBE3D/TRAIP/FBXL18/RNF130/NEURL4/MYLIP/FBXO27/UBE4A/SMURF1/PIAS1/ZNF598/TRIM13/FBXL8/RNF8/PDZRN4/ANAPC11/RNF19B/RNF216/RNF24/UBE3A/MGRN1/FBXW11/TOPORS/KIAA1586/RNF133/PIAS2/C10orf90/RABGEF1/SIAH2/BIRC3/ANAPC1/RNF7/RLIM/PDZD4/PRPF19/BTRC/PIAS4/NEURL2/RNF139/UBR2/LRSAM1/RNF121/TRAF6/MKRN1/BIRC7/FBXL22/MED12/FBXO44/IRF2BP1/UHRF2/RAG2/RNF138/CDC42/ASB1/RNF215/UBOX5/ZNF451/FBXO4/RNF148/RNF186/NHLRC3/PJA2	73
MF	GO:0140097	catalytic activity, acting on DNA	68/4733	213/17697	0.05232	0.4625	0.4332	RBBP8/TOP2A/TOP3A/EXO1/MCM4/TREX1/ERCC6L/MCM5/RAD54L/APEX2/MPG/NEIL3/FEN1/RAD51/ALKBH2/MCM2/CDC45/PIF1/GINS2/DMC1/GINS1/POLQ/GINS4/XRCC6/RPS3/ZRANB3/RFC2/MCM7/ISG20/TERF1/N6AMT1/HELQ/DSCC1/POLD4/RECQL5/CHTF8/ERCC5/POLE/MCM3/ERCC2/DNASE1L2/APLF/RECQL4/DFFB/POLM/XRCC3/XRCC1/EME1/METTL4/DDX11/DNA2/ENDOV/POLG2/DICER1/HELB/POLN/NEIL1/OGG1/WRN/FAN1/MGMT/MUTYH/ERCC1/ALKBH3/POLE2/TERF2/RAD54B/RAD9A	68
MF	GO:0005080	protein kinase C binding	20/4733	53/17697	0.05241	0.4625	0.4332	SDC4/TOP2A/SQSTM1/MARCKS/TIRAP/ADCY4/SRC/ADCY6/PICK1/TWF2/PRKCSH/PARD6G/DACT2/GRK5/PRKCB/PARD6B/C1QBP/HDAC9/PARD6A/ADAM9	20
MF	GO:0048365	Rac GTPase binding	25/4733	69/17697	0.05281	0.4625	0.4332	CYFIP1/CORO1C/NOXA1/SRGAP2/SRGAP2B/TIAM1/ARHGEF2/PAK4/DVL3/PAK1/FMNL1/DOCK3/PAK3/PREX1/EPS8L2/ARHGAP4/DVL1/MAP3K11/SRGAP3/ARHGDIA/ARHGAP17/WAS/SPATA13/RALBP1/PAK2	25
MF	GO:0019001	guanyl nucleotide binding	120/4733	394/17697	0.05336	0.4625	0.4332	TUBB6/GEM/RAB31/GNA15/RAC1/IRGQ/GBP2/TUBA1B/RAB33A/RABL2A/RTKN/TUBA1C/MX1/LRRK1/SCG5/LANCL2/TUBB/NUDT16/REM1/ARHGEF5/TGM2/RHOG/GPN1/RAB32/EFTUD2/GNAS/RAB13/TUBB4B/GTPBP3/EIF5B/RAB3D/NOA1/ARHGAP35/AK3/ARHGAP5/RAB19/RASD1/REM2/UPRT/TUBE1/GPN2/TUBB3/MRAS/TUBG2/TRIM23/RALA/RASEF/GNL3/NOLC1/GNAI2/RAB27A/EEF1A1/TUBB2A/CNGA1/DRG2/SEPHS1/IFT27/RASD2/RASL11A/TUBB4A/AGAP2/AK4/RAC2/ARL4C/RAB38/MOCS1/GLUD1/EEF1A2/SAMHD1/RHOF/MTG1/GIMAP8/RHOV/ARL16/EIF2S3/ARF4/RHOU/GIMAP2/DAPK1/RAB39B/RAB23/RAB2A/DNM1/RAB40B/TUBG1/RHOT2/RAB40C/GVINP1/DAP3/GNAQ/INSR/RAB15/ARF6/GSPT1/RAB1A/RAB34/LSG1/RAB37/THG1L/RALB/ARL2/ARL3/OLA1/GBP4/RRAGB/EHD3/CDC42/SPAG1/GUF1/GNAT3/TUFM/RAB28/ARL5A/EHD4/RRAS2/NME2/RAB1B/RAC3/RAB12/GFM1	120
MF	GO:0032561	guanyl ribonucleotide binding	120/4733	394/17697	0.05336	0.4625	0.4332	TUBB6/GEM/RAB31/GNA15/RAC1/IRGQ/GBP2/TUBA1B/RAB33A/RABL2A/RTKN/TUBA1C/MX1/LRRK1/SCG5/LANCL2/TUBB/NUDT16/REM1/ARHGEF5/TGM2/RHOG/GPN1/RAB32/EFTUD2/GNAS/RAB13/TUBB4B/GTPBP3/EIF5B/RAB3D/NOA1/ARHGAP35/AK3/ARHGAP5/RAB19/RASD1/REM2/UPRT/TUBE1/GPN2/TUBB3/MRAS/TUBG2/TRIM23/RALA/RASEF/GNL3/NOLC1/GNAI2/RAB27A/EEF1A1/TUBB2A/CNGA1/DRG2/SEPHS1/IFT27/RASD2/RASL11A/TUBB4A/AGAP2/AK4/RAC2/ARL4C/RAB38/MOCS1/GLUD1/EEF1A2/SAMHD1/RHOF/MTG1/GIMAP8/RHOV/ARL16/EIF2S3/ARF4/RHOU/GIMAP2/DAPK1/RAB39B/RAB23/RAB2A/DNM1/RAB40B/TUBG1/RHOT2/RAB40C/GVINP1/DAP3/GNAQ/INSR/RAB15/ARF6/GSPT1/RAB1A/RAB34/LSG1/RAB37/THG1L/RALB/ARL2/ARL3/OLA1/GBP4/RRAGB/EHD3/CDC42/SPAG1/GUF1/GNAT3/TUFM/RAB28/ARL5A/EHD4/RRAS2/NME2/RAB1B/RAC3/RAB12/GFM1	120
MF	GO:0070403	NAD+ binding	7/4733	14/17697	0.05368	0.4625	0.4332	SIRT6/SIRT3/GLUD1/SIRT2/HPGD/SIRT7/SIRT1	7
MF	GO:0042379	chemokine receptor binding	24/4733	66/17697	0.05474	0.4679	0.4383	CXCL13/CCL20/CCL3L3/CCL22/CCRL2/CXCL10/STAT3/CCR2/CCL3/CCL2/CCL17/CCL18/CXCL9/CXCL16/CXCL2/CXCL3/CKLF/CCL23/STAT1/CCL7/PPBP/CCL15/CCL27/JAK1	24
MF	GO:0016763	transferase activity, transferring pentosyl groups	18/4733	47/17697	0.05549	0.4679	0.4383	TYMP/SIRT6/QTRT1/PARP14/PARP2/HPRT1/PNP/NAMPT/TNKS2/PARP16/PARP11/MTAP/APRT/POGLUT1/PARP6/XXYLT1/PARP8/XYLT1	18
MF	GO:0035254	glutamate receptor binding	18/4733	47/17697	0.05549	0.4679	0.4383	SQSTM1/ADORA2A/HIP1/AKAP5/NETO2/HOMER2/HOMER1/GNAS/CAMK2A/SYNJ2BP/CACNG3/FLOT1/SCRIB/PRNP/CANX/FYN/DLG4/SHISA7	18
MF	GO:0051536	iron-sulfur cluster binding	23/4733	63/17697	0.05673	0.4717	0.4418	RSAD2/FXN/ABAT/RPS3/NUBP1/LIAS/NDUFS1/NDUFS7/POLE/RSAD1/ACO1/ERCC2/TYW1B/DPYD/MOCS1/DDX11/RFESD/DNA2/ISCU/NFS1/ISCA2/MUTYH/CDKAL1	23
MF	GO:0051540	metal cluster binding	23/4733	63/17697	0.05673	0.4717	0.4418	RSAD2/FXN/ABAT/RPS3/NUBP1/LIAS/NDUFS1/NDUFS7/POLE/RSAD1/ACO1/ERCC2/TYW1B/DPYD/MOCS1/DDX11/RFESD/DNA2/ISCU/NFS1/ISCA2/MUTYH/CDKAL1	23
MF	GO:0035173	histone kinase activity	8/4733	17/17697	0.05796	0.4751	0.445	AURKB/CDK1/AURKA/CCNB1/CDK2/PRKCA/CHEK1/PRKCB	8
MF	GO:0004520	endodeoxyribonuclease activity	16/4733	41/17697	0.05836	0.4751	0.445	RBBP8/EXO1/FEN1/RPS3/ZRANB3/ERCC5/DNASE1L2/APLF/XRCC3/XRCC1/EME1/DNA2/ENDOV/DICER1/FAN1/ERCC1	16
MF	GO:0003774	motor activity	45/4733	136/17697	0.05923	0.4751	0.445	MYO7A/KIF20A/KIF2C/KIF14/KIFC1/KIF4A/KIF15/KIF23/KIF24/KIF20B/KIF1C/MYO1E/KIF18A/SMC3/MYH10/KIF11/MYO5C/KLC1/WDR34/MYO5A/CENPE/DYNLRB1/MYL6/KIF4B/KLC3/DNHD1/MYH7B/KIF3C/MYH7/WDR60/MYH4/MYO9B/KLC4/MYL6B/DNAI2/MYH9/MYO18B/MYO3B/MYH6/KIF26B/TCTE3/STARD9/KIF19/KIFC2/DNAH6	45
MF	GO:0001614	purinergic nucleotide receptor activity	9/4733	20/17697	0.06051	0.4751	0.445	P2RY13/P2RX1/GPR34/P2RX6/P2RY10/P2RX5/P2RY1/PTAFR/P2RX7	9
MF	GO:0008329	signaling pattern recognition receptor activity	9/4733	20/17697	0.06051	0.4751	0.445	TLR8/CLEC7A/TLR4/FCN1/PGLYRP3/TLR2/COLEC12/PTAFR/TRIM5	9
MF	GO:0016502	nucleotide receptor activity	9/4733	20/17697	0.06051	0.4751	0.445	P2RY13/P2RX1/GPR34/P2RX6/P2RY10/P2RX5/P2RY1/PTAFR/P2RX7	9
MF	GO:0042288	MHC class I protein binding	9/4733	20/17697	0.06051	0.4751	0.445	DERL1/TUBB/VCP/TUBB4B/BCAP31/HLA-E/LILRB2/TAP1/KLRK1	9
MF	GO:0016493	C-C chemokine receptor activity	10/4733	23/17697	0.06185	0.4751	0.445	CXCR6/CCR1/CCRL2/CCR6/CCR2/CCR4/CCR5/CCR8/CXCR5/CX3CR1	10
MF	GO:0030215	semaphorin receptor binding	10/4733	23/17697	0.06185	0.4751	0.445	SEMA4C/PLXNB1/SEMA7A/SEMA3G/SEMA6C/SEMA6B/SEMA3B/SEMA5B/SEMA4D/SEMA5A	10
MF	GO:0046966	thyroid hormone receptor binding	12/4733	29/17697	0.06221	0.4751	0.445	GAS2L1/ARID5A/TRIP6/MED4/OASL/MED24/TAF11/ZNHIT3/TAF7/MED12/NUP62/NCOR1	12
MF	GO:0001637	G protein-coupled chemoattractant receptor activity	11/4733	26/17697	0.06233	0.4751	0.445	CXCR6/CCR1/CCRL2/CCR6/CCR2/CCR4/CCR5/GPR35/CCR8/CXCR5/CX3CR1	11
MF	GO:0004950	chemokine receptor activity	11/4733	26/17697	0.06233	0.4751	0.445	CXCR6/CCR1/CCRL2/CCR6/CCR2/CCR4/CCR5/GPR35/CCR8/CXCR5/CX3CR1	11
MF	GO:0030371	translation repressor activity	11/4733	26/17697	0.06233	0.4751	0.445	TYMS/EIF4EBP1/PAIP2B/CIRBP/DHFR/FMR1/SAMD4B/CPEB1/ZNF540/RBM3/RARA	11
MF	GO:0035591	signaling adaptor activity	28/4733	80/17697	0.0639	0.4838	0.4531	SH2B2/SLA/KSR1/SOCS2/SH2D2A/GAB2/CLNK/SRC/HOMER1/SH2D1A/STAM/GRAP2/MPP7/ARHGAP4/LAT/SLA2/SH2D3A/CRK/SH2D3C/CHN1/DOK2/LDLRAP1/CDC42SE2/AKAP13/CHN2/LASP1/ARHGAP1/SHC1	28
MF	GO:0017124	SH3 domain binding	43/4733	130/17697	0.06428	0.4838	0.4531	CASP9/CIT/MICAL1/PTPN6/PTTG1/SIRPA/ADAM12/CCDC6/ADAM19/SH2D2A/NOXA1/AKAP5/PLSCR4/GPX1/DOCK1/ARHGAP31/HIP1R/DOCK3/SH3GL1/PAK3/VASP/RAPGEF1/DNAJC6/CRK/AFAP1/DTX1/CYBA/ADAM15/UVRAG/CD3E/RUFY2/CD2AP/DNM1/ARHGAP17/NCF1/WASF2/ARHGAP1/TOM1L1/WAS/ADAM9/FMN1/ILK/RAD9A	43
MF	GO:0005088	Ras guanyl-nucleotide exchange factor activity	45/4733	137/17697	0.06603	0.4938	0.4625	TIAM2/PLEKHG2/ARHGEF39/ARHGEF40/RASGEF1B/SBF1/ARHGEF18/FGD2/RANGRF/MCF2L2/ARHGEF12/ARHGEF5/TIAM1/ARHGEF2/DOCK1/RAPGEF5/DOCK3/RASGRF2/PREX1/SBF2/PLEKHG1/EPS8L2/VAV2/SH3BP5L/PLEKHG7/RASGRP4/RAPGEF1/DENND2D/ECT2/RCC1/RABGEF1/RGL3/RAPGEF2/RALGPS1/OBSCN/DENND3/TRAPPC4/AKAP13/BCR/RIN2/MCF2L/NET1/DENND6A/SPATA13/ARHGEF26	45
MF	GO:1901981	phosphatidylinositol phosphate binding	52/4733	161/17697	0.06752	0.5017	0.47	PHLDA3/TIRAP/SESTD1/NCF4/RACGAP1/ANXA2P2/HIP1/FGD2/PLEKHN1/GAB2/ANXA2/ARHGAP9/LANCL2/PLEKHA1/DAPP1/MAPKAP1/BTK/SDCBP/ATP13A2/KCNJ2/PFN2/HIP1R/NRGN/GSDMC/TPCN1/PLEKHA2/TWF2/PIRT/ARAP1/ADAP2/ARAP3/GBF1/SH3PXD2B/SNX11/SNX19/PLEKHA8/SAP30L/SDCBP2/PLEKHB2/KRIT1/OBSCN/CLVS1/LDLRAP1/RPH3A/WDR45/GSDMA/NCF1/GSDMB/ARHGAP32/RAG2/PLCB1/PLEKHA3	52
MF	GO:0016887	ATPase activity	116/4733	384/17697	0.06913	0.5105	0.4782	MYO7A/KIF20A/KIF2C/KIF14/KIFC1/KIF4A/KIF15/TOP2A/KIF23/ABCC1/HSPA2/ABCG1/KIF24/KIF20B/ERCC6L/ATP6V0D1/KIF1C/MCM5/MYO1E/KIF18A/RAD54L/TOR3A/MYH10/HSPA5/MSH6/HSPA1A/KIF11/ATP6V0B/RAD51/ABCD1/WDR34/PMS2P1/TDRD9/CARNS1/ATP13A1/MCM2/ABCD2/CENPE/ATP13A4/HSPA9/VWA8/VCP/MYL6/PIF1/ATP2A1/ATP13A2/KIF4B/DMC1/MORC2/ATP6V1E1/POLQ/PFN2/ATP6V0C/ZRANB3/RFC2/MCM7/ATP1B1/CDK7/SMARCA4/ABCE1/HELQ/DNHD1/DSCC1/ANXA5/ATP6V1A/ABCA1/FIGNL1/CHTF8/ATP2B4/TAP1/KIF3C/MYH7/RNF213/ABCC6/ATP1B3/ABCB4/ERCC2/DDX17/ATAD2/WDR60/GTF2H2/MYH4/PMS2P5/ATAD1/GTF2H1/MYO9B/ABCA5/XRCC3/HSPA6/ATP6V1G1/DDX11/DNAI2/KATNAL2/DNA2/MYH9/MDN1/HSPA1L/MNAT1/HELB/HSPA14/LMBRD1/ATP6V1E2/ABCA3/OLA1/MLH3/WRN/MYH6/ABCB8/KIF19/PSMC5/PEX1/PMS1/RALBP1/KIFC2/DNAH6/RAD54B	116
MF	GO:0003777	microtubule motor activity	29/4733	84/17697	0.07056	0.5179	0.4851	KIF20A/KIF2C/KIF14/KIFC1/KIF4A/KIF15/KIF23/KIF24/KIF20B/KIF1C/KIF18A/SMC3/KIF11/KLC1/WDR34/CENPE/DYNLRB1/KIF4B/KLC3/DNHD1/KIF3C/WDR60/KLC4/DNAI2/KIF26B/STARD9/KIF19/KIFC2/DNAH6	29
MF	GO:0000340	RNA 7-methylguanosine cap binding	6/4733	12/17697	0.07295	0.5194	0.4865	CYFIP1/DCPS/EIF4E2/EIF4E3/NCBP2/GEMIN5	6
MF	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	6/4733	12/17697	0.07295	0.5194	0.4865	SLC35A2/SLC35E4/SLC35B1/SLC35D2/SLC35D1/SLC35B4	6
MF	GO:0030898	actin-dependent ATPase activity	6/4733	12/17697	0.07295	0.5194	0.4865	MYO7A/MYH10/MYL6/MYH7/MYH9/MYH6	6
MF	GO:0031994	insulin-like growth factor I binding	6/4733	12/17697	0.07295	0.5194	0.4865	IGFBP4/IGF1R/IGFBP3/ITGA6/INSR/IGFBP6	6
MF	GO:0035325	Toll-like receptor binding	6/4733	12/17697	0.07295	0.5194	0.4865	TIRAP/UNC93B1/TOLLIP/TLR2/TLR6/S100A8	6
MF	GO:0003779	actin binding	129/4733	431/17697	0.07364	0.5212	0.4882	MYO7A/PLEC/ANLN/FSCN1/ABLIM1/SMTN/MICAL1/MARCKS/SNTB1/CYFIP1/GAS2L3/MSRB1/YWHAH/MYO1E/CEACAM1/CORO1C/HIP1/KIF18A/KLHL5/NF2/FHOD1/CAPZB/SYN1/MYH10/GSN/CTTN/SVIL/WIPF2/LSP1/MYO5C/HOMER2/VASH1/MICAL2/TMOD2/MYO5A/PDLIM4/BLOC1S6/GCSAM/BCL7B/CAPG/CORO1B/PLS1/PPP1R18/ADD3/FMNL1/KLHL3/MYOT/PFN2/CCR5/HIP1R/ARPC1B/PDLIM7/PICK1/PHACTR2/EPS8L2/TMSB4Y/SPTBN1/EZR/CORO1A/VASP/AIF1/TRIOBP/TWF2/LIMCH1/CFL1/PARVB/ACTN4/DIAPH3/COTL1/SPTAN1/TPM2/ARPC5/NOD2/MYBPC3/MYH7B/MAEA/XIRP2/CAPZA1/MYH7/EMD/MAP1S/NRAP/FXYD5/TNNC1/SHROOM1/PRKCE/MYH4/AFAP1/ACTR3B/WDR1/SAMD14/EPB41L2/MYO9B/MICAL3/CTNNA1/CORO7/SYNE3/SHROOM3/TMSB15A/VILL/ALDOA/MYH9/MYOM1/EPB41/ABLIM2/UTRN/SSH2/CNN2/MAP1A/TPM1/AIF1L/MYO18B/CACNB2/PSTPIP2/MYO3B/PPP1R9B/WASF2/WHAMM/LASP1/TMEM201/MYH6/MED28/ALKBH4/WAS/MYBPC2/TRPC5/SYNE2/FMN1/ADD2	129
MF	GO:0002020	protease binding	42/4733	128/17697	0.07472	0.5241	0.4909	FURIN/ITGA3/IL1R1/SERPINB6/RFFL/TIMP4/TIMP2/ANXA2P2/TNF/BRCA2/DERL1/NOL3/SERPINE1/ANXA2/LDLR/ADAMTSL4/SYVN1/CSTA/CFLAR/VCP/TRIP4/CST3/DVL3/SRI/CD177/TYSND1/PINK1/A2M/FLOT1/LRP1/BDKRB2/NDUFS7/PARK7/TIMP1/RAD23A/INSL3/F3/PRNP/RIPK2/RNF139/TIMP3/CHMP3	42
MF	GO:0035257	nuclear hormone receptor binding	49/4733	152/17697	0.07621	0.5241	0.4909	VDR/NR4A1/NR4A3/PPARG/GAS2L1/ARID5A/YWHAH/TGFB1I1/STAT3/SRC/PPARGC1B/TRIP6/ARRB1/TRIP4/CRY1/MED4/OASL/FLT3/TCF7L2/CDK7/SMARCA4/PIAS1/ACTN4/MED24/ASXL1/TAF10/RXRA/SUMO1/ARID1A/PARK7/TOB2/NCOA4/TAF11/ZNHIT3/DDX54/CEBPB/PIAS2/PADI2/TAF7/ESR1/PRKCB/BAZ2A/STAT1/MED12/KDM4C/BCAS3/NUP62/NCOR1/SIRT1	49
MF	GO:0005070	SH3/SH2 adaptor activity	19/4733	52/17697	0.07778	0.5241	0.4909	SH2B2/SLA/SOCS2/SH2D2A/CLNK/SRC/SH2D1A/STAM/GRAP2/ARHGAP4/LAT/SLA2/SH2D3A/CRK/SH2D3C/CHN1/CHN2/LASP1/ARHGAP1	19
MF	GO:0005548	phospholipid transporter activity	19/4733	52/17697	0.07778	0.5241	0.4909	ABCG1/PCTP/MFSD2A/PRELID1/PLSCR4/PITPNA/C2CD2L/PITPNM1/ABCA1/STARD10/TMEM30A/ABCB4/PLEKHA8/PLSCR2/CETP/TNFAIP8L3/GLTPD2/ANO4/PLEKHA3	19
MF	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	7/4733	15/17697	0.07804	0.5241	0.4909	MBOAT7/AGPAT3/AGPAT2/LPCAT2/LCLAT1/TAZ/CRLS1	7
MF	GO:0042171	lysophosphatidic acid acyltransferase activity	7/4733	15/17697	0.07804	0.5241	0.4909	MBOAT7/AGPAT3/AGPAT2/LPCAT2/LCLAT1/TAZ/CRLS1	7
MF	GO:0042809	vitamin D receptor binding	7/4733	15/17697	0.07804	0.5241	0.4909	MED4/MED24/RXRA/TOB2/TAF11/TAF7/MED12	7
MF	GO:1990404	protein ADP-ribosylase activity	7/4733	15/17697	0.07804	0.5241	0.4909	PARP14/PARP2/TNKS2/PARP16/PARP11/PARP6/PARP8	7
MF	GO:0016791	phosphatase activity	83/4733	270/17697	0.0784	0.5241	0.4909	PTPN13/ACPP/DUSP10/DUSP4/CDKN3/PTPRF/ACP5/PTPN6/DLGAP5/PPM1N/DUSP6/PFKFB3/CPPED1/PTPN7/SBF1/CDC25A/MTMR3/PPP2R1A/NT5DC2/PPP1CB/PTPN1/CDC25C/PPTC7/PTPN14/NUDT16/DUSP5/INPP4A/PDXP/PALD1/PFKFB4/EPHX2/PTPN4/PTPN9/PIKFYVE/SGPP1/EYA2/LHPP/DUSP16/PTPRC/IMPA2/TIMM50/DUSP23/DUSP22/ACP6/PFKFB2/PPP2CA/PTPN18/PPP1R3E/STYXL1/PPA2/PPP5C/PPM1G/TAB1/DNAJC6/CAMK2G/PTPRM/INPP1/PHLPP1/PSPH/PTPMT1/MTMR14/DUSP18/DUPD1/ENOPH1/CDC14B/PTPRS/NT5E/SSH2/ACP1/PPP2R3B/DUSP14/PPP6C/PPM1J/PPM1K/MYH6/NT5C2/PGAM5/CDC25B/PPM1L/LPIN1/PPP1R3B/PTP4A3/DUSP1	83
MF	GO:0048029	monosaccharide binding	26/4733	75/17697	0.07994	0.5241	0.4909	P4HA2/HK1/MRC1/PFKP/LGALS9/GPI/SLC2A8/HK2/SLC2A3/CD207/PAM/GALK2/M6PR/GALK1/LMAN2/BSG/ALDOA/OGFOD1/P4HTM/COLEC12/PLOD3/MANBA/PFKL/ALDOB/OGFOD2/ALKBH3	26
MF	GO:0038024	cargo receptor activity	29/4733	85/17697	0.08066	0.5241	0.4909	MRC1/TFRC/TMPRSS3/HIP1/LRP8/LDLR/PRG4/SORL1/LRP10/ARRB1/HIP1R/SCARF1/CXCL16/ABCA1/VTN/AP2S1/LRP1/ILDR1/FPR2/CUBN/CFI/LRP12/CD6/LDLRAP1/COLEC12/LRP6/APOBR/INSR/TINAGL1	29
MF	GO:0000217	DNA secondary structure binding	10/4733	24/17697	0.08144	0.5241	0.4909	HMGB3/RBBP8/HMGB1/MSH6/NEIL3/ERCC5/RECQL4/POT1/XRCC3/WRN	10
MF	GO:0001965	G-protein alpha-subunit binding	10/4733	24/17697	0.08144	0.5241	0.4909	GPSM2/HTR2A/RIC8A/NUCB1/RGS19/DRD1/PPP5C/RGS1/F2R/RIC8B	10
MF	GO:0051119	sugar transmembrane transporter activity	10/4733	24/17697	0.08144	0.5241	0.4909	SLC2A8/SLC2A3/SLC5A3/SLC2A4/SLC45A3/SLC2A11/SLC2A14/SLC23A2/SLC5A4/PPBP	10
MF	GO:0004602	glutathione peroxidase activity	9/4733	21/17697	0.08155	0.5241	0.4909	ALOX5AP/GPX1/GPX4/PRDX6/GSTT1/MGST2/MGST3/GSTK1/GSTZ1	9
MF	GO:0016411	acylglycerol O-acyltransferase activity	9/4733	21/17697	0.08155	0.5241	0.4909	MBOAT7/AGPAT3/AGPAT2/LPCAT2/MOGAT1/DGAT2/LCLAT1/TAZ/CRLS1	9
MF	GO:0038187	pattern recognition receptor activity	9/4733	21/17697	0.08155	0.5241	0.4909	TLR8/CLEC7A/TLR4/FCN1/PGLYRP3/TLR2/COLEC12/PTAFR/TRIM5	9