ONTOLOGY ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count KEGG hsa00500 Starch and sucrose metabolism 3/64 36/8135 0.002756 0.2893 0.2814 G6PC2/GBA3/HKDC1 3 KEGG hsa04080 Neuroactive ligand-receptor interaction 8/64 353/8135 0.006143 0.3225 0.3136 GHRH/CORT/GABRP/GCGR/GABRA6/MTNR1A/PATE2/MC4R 8 KEGG hsa00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin 2/64 24/8135 0.01504 0.515 0.5008 HS6ST3/HS3ST3B1 2 KEGG hsa00052 Galactose metabolism 2/64 31/8135 0.02447 0.515 0.5008 G6PC2/HKDC1 2 KEGG hsa04610 Complement and coagulation cascades 3/64 85/8135 0.02905 0.515 0.5008 C6/F12/MASP1 3 KEGG hsa04742 Taste transduction 3/64 86/8135 0.02993 0.515 0.5008 PDE1B/TAS2R14/GABRA6 3 KEGG hsa05032 Morphine addiction 3/64 91/8135 0.03457 0.515 0.5008 GABRP/PDE1B/GABRA6 3 KEGG hsa05033 Nicotine addiction 2/64 40/8135 0.03924 0.515 0.5008 GABRP/GABRA6 2 KEGG hsa04973 Carbohydrate digestion and absorption 2/64 47/8135 0.05252 0.6128 0.5959 G6PC2/HKDC1 2 KEGG hsa00010 Glycolysis / Gluconeogenesis 2/64 67/8135 0.09733 0.783 0.7614 G6PC2/HKDC1 2 KEGG hsa05218 Melanoma 2/64 72/8135 0.1098 0.783 0.7614 FGF17/FGF20 2 KEGG hsa04020 Calcium signaling pathway 4/64 240/8135 0.1197 0.783 0.7614 PDE1B/FGF17/FGF20/CASQ1 4 KEGG hsa00450 Selenocompound metabolism 1/64 17/8135 0.1258 0.783 0.7614 MARS2 1 KEGG hsa00061 Fatty acid biosynthesis 1/64 18/8135 0.1327 0.783 0.7614 OLAH 1 KEGG hsa04146 Peroxisome 2/64 82/8135 0.1359 0.783 0.7614 MPV17L2/PIPOX 2 KEGG hsa00100 Steroid biosynthesis 1/64 20/8135 0.1463 0.783 0.7614 SOAT2 1 KEGG hsa04530 Tight junction 3/64 169/8135 0.1474 0.783 0.7614 IGSF5/CLDN20/PARD6B 3 KEGG hsa04727 GABAergic synapse 2/64 89/8135 0.1549 0.783 0.7614 GABRP/GABRA6 2 KEGG hsa04658 Th1 and Th2 cell differentiation 2/64 92/8135 0.1632 0.783 0.7614 RBPJL/IL12RB2 2 KEGG hsa05150 Staphylococcus aureus infection 2/64 96/8135 0.1743 0.783 0.7614 DEFA5/MASP1 2 KEGG hsa04621 NOD-like receptor signaling pathway 3/64 184/8135 0.176 0.783 0.7614 DEFA5/PYDC1/CARD18 3 KEGG hsa04010 MAPK signaling pathway 4/64 294/8135 0.2001 0.783 0.7614 RASGRP4/FGF17/FGF20/MAP3K6 4 KEGG hsa04060 Cytokine-cytokine receptor interaction 4/64 295/8135 0.2017 0.783 0.7614 GDF10/IL12RB2/TNFSF18/CTF1 4 KEGG hsa04744 Phototransduction 1/64 29/8135 0.205 0.783 0.7614 GNAT1 1 KEGG hsa04922 Glucagon signaling pathway 2/64 107/8135 0.2057 0.783 0.7614 G6PC2/GCGR 2 KEGG hsa03008 Ribosome biogenesis in eukaryotes 2/64 109/8135 0.2114 0.783 0.7614 MDN1/SPATA5 2 KEGG hsa04015 Rap1 signaling pathway 3/64 210/8135 0.2286 0.783 0.7614 FGF17/PARD6B/FGF20 3 KEGG hsa00051 Fructose and mannose metabolism 1/64 33/8135 0.2298 0.783 0.7614 HKDC1 1 KEGG hsa00350 Tyrosine metabolism 1/64 36/8135 0.248 0.783 0.7614 TYR 1 KEGG hsa01250 Biosynthesis of nucleotide sugars 1/64 37/8135 0.2539 0.783 0.7614 HKDC1 1 KEGG hsa00260 Glycine, serine and threonine metabolism 1/64 40/8135 0.2714 0.783 0.7614 PIPOX 1 KEGG hsa04014 Ras signaling pathway 3/64 232/8135 0.2752 0.783 0.7614 RASGRP4/FGF17/FGF20 3 KEGG hsa05171 Coronavirus disease - COVID-19 3/64 232/8135 0.2752 0.783 0.7614 C6/RPS11/MASP1 3 KEGG hsa04975 Fat digestion and absorption 1/64 43/8135 0.2886 0.783 0.7614 NPC1L1 1 KEGG hsa04910 Insulin signaling pathway 2/64 137/8135 0.2932 0.783 0.7614 G6PC2/HKDC1 2 KEGG hsa04151 PI3K-Akt signaling pathway 4/64 354/8135 0.3034 0.783 0.7614 G6PC2/FGF17/FGF20/LAMA5 4 KEGG hsa03050 Proteasome 1/64 46/8135 0.3053 0.783 0.7614 PSMA8 1 KEGG hsa04930 Type II diabetes mellitus 1/64 46/8135 0.3053 0.783 0.7614 HKDC1 1 KEGG hsa05017 Spinocerebellar ataxia 2/64 143/8135 0.3107 0.783 0.7614 RBPJL/PSMA8 2 KEGG hsa00520 Amino sugar and nucleotide sugar metabolism 1/64 49/8135 0.3217 0.783 0.7614 HKDC1 1 KEGG hsa05224 Breast cancer 2/64 147/8135 0.3223 0.783 0.7614 FGF17/FGF20 2 KEGG hsa04723 Retrograde endocannabinoid signaling 2/64 148/8135 0.3252 0.783 0.7614 GABRP/GABRA6 2 KEGG hsa04979 Cholesterol metabolism 1/64 50/8135 0.3271 0.783 0.7614 SOAT2 1 KEGG hsa05226 Gastric cancer 2/64 149/8135 0.3281 0.783 0.7614 FGF17/FGF20 2 KEGG hsa00600 Sphingolipid metabolism 1/64 52/8135 0.3377 0.7879 0.7662 ENPP7 1 KEGG hsa04630 JAK-STAT signaling pathway 2/64 162/8135 0.3655 0.7989 0.7769 IL12RB2/CTF1 2 KEGG hsa04330 Notch signaling pathway 1/64 59/8135 0.3735 0.7989 0.7769 RBPJL 1 KEGG hsa00310 Lysine degradation 1/64 63/8135 0.3932 0.7989 0.7769 PIPOX 1 KEGG hsa04927 Cortisol synthesis and secretion 1/64 65/8135 0.4028 0.7989 0.7769 NR5A1 1 KEGG hsa05321 Inflammatory bowel disease 1/64 65/8135 0.4028 0.7989 0.7769 IL12RB2 1 KEGG hsa00970 Aminoacyl-tRNA biosynthesis 1/64 66/8135 0.4075 0.7989 0.7769 MARS2 1 KEGG hsa04920 Adipocytokine signaling pathway 1/64 69/8135 0.4215 0.7989 0.7769 G6PC2 1 KEGG hsa04924 Renin secretion 1/64 69/8135 0.4215 0.7989 0.7769 PDE1B 1 KEGG hsa04622 RIG-I-like receptor signaling pathway 1/64 70/8135 0.4261 0.7989 0.7769 OTUD5 1 KEGG hsa05120 Epithelial cell signaling in Helicobacter pylori infection 1/64 70/8135 0.4261 0.7989 0.7769 IGSF5 1 KEGG hsa05230 Central carbon metabolism in cancer 1/64 70/8135 0.4261 0.7989 0.7769 HKDC1 1 KEGG hsa04918 Thyroid hormone synthesis 1/64 75/8135 0.4485 0.8215 0.7989 DUOXA2 1 KEGG hsa04740 Olfactory transduction 4/64 440/8135 0.4582 0.8215 0.7989 OR2W1/PDE1B/OR3A2/OR7A5 4 KEGG hsa05130 Pathogenic Escherichia coli infection 2/64 197/8135 0.4616 0.8215 0.7989 MYO5C/CLDN20 2 KEGG hsa05203 Viral carcinogenesis 2/64 204/8135 0.4799 0.828 0.8052 RBPJL/RANBP1 2 KEGG hsa05165 Human papillomavirus infection 3/64 331/8135 0.4863 0.828 0.8052 RBPJL/PARD6B/LAMA5 3 KEGG hsa05207 Chemical carcinogenesis - receptor activation 2/64 212/8135 0.5003 0.828 0.8052 FGF17/FGF20 2 KEGG hsa04512 ECM-receptor interaction 1/64 88/8135 0.5028 0.828 0.8052 LAMA5 1 KEGG hsa04810 Regulation of actin cytoskeleton 2/64 218/8135 0.5153 0.828 0.8052 FGF17/FGF20 2 KEGG hsa05222 Small cell lung cancer 1/64 92/8135 0.5185 0.828 0.8052 LAMA5 1 KEGG hsa04713 Circadian entrainment 1/64 97/8135 0.5373 0.828 0.8052 MTNR1A 1 KEGG hsa05215 Prostate cancer 1/64 97/8135 0.5373 0.828 0.8052 KLK3 1 KEGG hsa04916 Melanogenesis 1/64 101/8135 0.5519 0.828 0.8052 TYR 1 KEGG hsa05146 Amoebiasis 1/64 102/8135 0.5555 0.828 0.8052 LAMA5 1 KEGG hsa04928 Parathyroid hormone synthesis, secretion and action 1/64 106/8135 0.5695 0.828 0.8052 SOST 1 KEGG hsa04931 Insulin resistance 1/64 108/8135 0.5763 0.828 0.8052 G6PC2 1 KEGG hsa04066 HIF-1 signaling pathway 1/64 109/8135 0.5797 0.828 0.8052 HKDC1 1 KEGG hsa05145 Toxoplasmosis 1/64 112/8135 0.5896 0.828 0.8052 LAMA5 1 KEGG hsa04670 Leukocyte transendothelial migration 1/64 114/8135 0.5962 0.828 0.8052 CLDN20 1 KEGG hsa04724 Glutamatergic synapse 1/64 114/8135 0.5962 0.828 0.8052 SHANK1 1 KEGG hsa01200 Carbon metabolism 1/64 115/8135 0.5994 0.828 0.8052 HKDC1 1 KEGG hsa04935 Growth hormone synthesis, secretion and action 1/64 119/8135 0.612 0.828 0.8052 GHRH 1 KEGG hsa04152 AMPK signaling pathway 1/64 120/8135 0.6151 0.828 0.8052 G6PC2 1 KEGG hsa04110 Cell cycle 1/64 126/8135 0.6332 0.8284 0.8056 CDC45 1 KEGG hsa05020 Prion disease 2/64 273/8135 0.6385 0.8284 0.8056 C6/PSMA8 2 KEGG hsa00230 Purine metabolism 1/64 128/8135 0.639 0.8284 0.8056 PDE1B 1 KEGG hsa04068 FoxO signaling pathway 1/64 131/8135 0.6476 0.8293 0.8064 G6PC2 1 KEGG hsa05322 Systemic lupus erythematosus 1/64 136/8135 0.6615 0.8368 0.8138 C6 1 KEGG hsa04120 Ubiquitin mediated proteolysis 1/64 142/8135 0.6774 0.8452 0.8219 HERC1 1 KEGG hsa04514 Cell adhesion molecules 1/64 149/8135 0.6951 0.8452 0.8219 CLDN20 1 KEGG hsa04934 Cushing syndrome 1/64 155/8135 0.7095 0.8452 0.8219 NR5A1 1 KEGG hsa04390 Hippo signaling pathway 1/64 157/8135 0.7141 0.8452 0.8219 PARD6B 1 KEGG hsa05160 Hepatitis C 1/64 157/8135 0.7141 0.8452 0.8219 CLDN20 1 KEGG hsa03010 Ribosome 1/64 158/8135 0.7164 0.8452 0.8219 RPS11 1 KEGG hsa04310 Wnt signaling pathway 1/64 167/8135 0.7362 0.8589 0.8353 SOST 1 KEGG hsa04360 Axon guidance 1/64 182/8135 0.7663 0.8842 0.8598 PARD6B 1 KEGG hsa05034 Alcoholism 1/64 187/8135 0.7756 0.8852 0.8608 SLC29A2 1 KEGG hsa05202 Transcriptional misregulation in cancer 1/64 193/8135 0.7862 0.8856 0.8612 DEFA5 1 KEGG hsa04510 Focal adhesion 1/64 201/8135 0.7996 0.8856 0.8612 LAMA5 1 KEGG hsa05169 Epstein-Barr virus infection 1/64 202/8135 0.8012 0.8856 0.8612 RBPJL 1 KEGG hsa05166 Human T-cell leukemia virus 1 infection 1/64 222/8135 0.831 0.9089 0.8838 RANBP1 1 KEGG hsa05131 Shigellosis 1/64 247/8135 0.8621 0.919 0.8937 HKDC1 1 KEGG hsa05132 Salmonella infection 1/64 249/8135 0.8643 0.919 0.8937 RHOB 1 KEGG hsa04144 Endocytosis 1/64 251/8135 0.8665 0.919 0.8937 PARD6B 1 KEGG hsa05012 Parkinson disease 1/64 266/8135 0.8819 0.926 0.9004 PSMA8 1 KEGG hsa05016 Huntington disease 1/64 306/8135 0.9149 0.9511 0.9249 PSMA8 1 KEGG hsa05014 Amyotrophic lateral sclerosis 1/64 364/8135 0.9472 0.9738 0.947 PSMA8 1 KEGG hsa05010 Alzheimer disease 1/64 384/8135 0.9553 0.9738 0.947 PSMA8 1 KEGG hsa05022 Pathways of neurodegeneration - multiple diseases 1/64 476/8135 0.9792 0.9823 0.9552 PSMA8 1 KEGG hsa05168 Herpes simplex virus 1 infection 1/64 495/8135 0.9823 0.9823 0.9552 ZNF324 1