ONTOLOGY	ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	qvalue	geneID	Count
KEGG	hsa05022	Pathways of neurodegeneration - multiple diseases	53/515	476/8135	3.178e-05	0.007142	0.006884	TUBA3C/NDUFB5/DVL3/SDHB/TNFRSF1B/KLC1/DNAH8/NDUFB8/MAPK13/PSMA6/RAF1/PSMA2/CHMP2B/OPTN/KIF5C/RAB1A/UQCRC2/NDUFA12/DVL1/DCTN6/COX7A2L/PSMA4/VDAC2/COX7B/NEFL/CCS/AXIN2/TUBB1/ZFYVE1/NDUFC2/NDUFV2/VCP/PSMB5/NDUFB3/HTT/TUBB/NDUFV1/GNAQ/CALM2/NDUFB1/UBE2J2/UBE2G2/GRIN2A/UQCRHL/UQCRFS1/DCTN4/ATXN3/NDUFA13/PSMB1/TRPC3/MAP2K7/NDUFAB1/CSNK1E	53
KEGG	hsa05014	Amyotrophic lateral sclerosis	43/515	364/8135	4.638e-05	0.007142	0.006884	NUP62/TUBA3C/NDUFB5/NUP210/SDHB/TNFRSF1B/KLC1/DNAH8/NDUFB8/MAPK13/PSMA6/PSMA2/CHMP2B/OPTN/KIF5C/RAB1A/UQCRC2/NDUFA12/DCTN6/COX7A2L/PSMA4/COX7B/NEFL/CCS/TUBB1/NDUFC2/NDUFV2/VCP/PSMB5/NDUFB3/TUBB/NDUFV1/MATR3/NDUFB1/GRIN2A/UQCRHL/UQCRFS1/DCTN4/NDUFA13/PSMB1/NUP214/NUP188/NDUFAB1	43
KEGG	hsa00190	Oxidative phosphorylation	20/515	134/8135	0.0002704	0.02273	0.0219	NDUFB5/SDHB/NDUFB8/ATP6V1G3/UQCRC2/NDUFA12/COX7A2L/COX7B/NDUFC2/NDUFV2/NDUFB3/PPA1/NDUFV1/ATP6V0E1/NDUFB1/UQCRHL/UQCRFS1/NDUFA13/ATP6V1F/NDUFAB1	20
KEGG	hsa05012	Parkinson disease	32/515	266/8135	0.0003151	0.02273	0.0219	TUBA3C/NDUFB5/SDHB/KLC1/NDUFB8/PSMA6/PSMA2/KIF5C/UQCRC2/NDUFA12/COX7A2L/PSMA4/VDAC2/COX7B/TUBB1/NDUFC2/NDUFV2/PSMB5/NDUFB3/SLC39A8/GNAS/TUBB/NDUFV1/CALM2/NDUFB1/UBE2J2/UBE2G2/UQCRHL/UQCRFS1/NDUFA13/PSMB1/NDUFAB1	32
KEGG	hsa05208	Chemical carcinogenesis - reactive oxygen species	28/515	223/8135	0.0003689	0.02273	0.0219	NDUFB5/PRKD2/MGST1/SDHB/NDUFB8/MAPK13/RAF1/MGST2/UQCRC2/NDUFA12/COX7A2L/VDAC2/COX7B/NDUFC2/NDUFV2/NDUFB3/AHR/CHUK/NDUFV1/SRC/NDUFB1/UQCRHL/UQCRFS1/MAP3K14/GSTO1/NDUFA13/MAP2K7/NDUFAB1	28
KEGG	hsa05020	Prion disease	32/515	273/8135	0.0005012	0.02573	0.0248	TUBA3C/NDUFB5/SDHB/KLC1/NDUFB8/MAPK13/PSMA6/PSMA2/KIF5C/UQCRC2/NDUFA12/COX7A2L/PSMA4/VDAC2/COX7B/TUBB1/NDUFC2/NDUFV2/PSMB5/NDUFB3/C5/TUBB/NDUFV1/NDUFB1/GRIN2A/UQCRHL/UQCRFS1/RAC2/HSPA1L/NDUFA13/PSMB1/NDUFAB1	32
KEGG	hsa05016	Huntington disease	34/515	306/8135	0.0008913	0.03922	0.0378	TUBA3C/NDUFB5/SDHB/KLC1/DNAH8/NDUFB8/PSMA6/PSMA2/CREBBP/KIF5C/UQCRC2/NDUFA12/DCTN6/COX7A2L/PSMA4/VDAC2/COX7B/TUBB1/NDUFC2/NDUFV2/PSMB5/NDUFB3/HTT/TUBB/NDUFV1/GNAQ/NDUFB1/UQCRHL/UQCRFS1/DCTN4/NDUFA13/PSMB1/MAP2K7/NDUFAB1	34
KEGG	hsa05132	Salmonella infection	28/515	249/8135	0.002078	0.08001	0.07711	CYTH4/TUBA3C/DYNC1H1/ARPC3/CYTH1/LY96/KLC1/PAK3/MAPK13/RAF1/KIF5C/DCTN6/MYL7/SNX9/FHOD1/TUBB1/RAB9A/ARL8B/CHUK/TUBB/MYO6/DYNLT1/PLEKHM1/DCTN4/FLNB/CYFIP2/MAP2K7/DNM2	28
KEGG	hsa04723	Retrograde endocannabinoid signaling	19/515	148/8135	0.002426	0.08116	0.07822	DAGLB/NDUFB5/NDUFB8/MAPK13/GABRB3/GNG5/NDUFA12/NDUFC2/NDUFV2/NDUFB3/GNB1/NDUFV1/GNAQ/GABRA2/NDUFB1/SLC17A6/NDUFA13/MGLL/NDUFAB1	19
KEGG	hsa04810	Regulation of actin cytoskeleton	25/515	218/8135	0.002714	0.08116	0.07822	EZR/ITGAL/ARPC3/DIAPH1/VCL/PAK2/PAK3/RAF1/ACTN1/TMSB4X/DIAPH3/MYL7/ARHGEF12/TIAM1/GNA12/SPATA13/PDGFA/SRC/MRAS/PIP5K1B/MYH9/RAC2/ITGAE/SSH1/CYFIP2	25
KEGG	hsa05130	Pathogenic Escherichia coli infection	23/515	197/8135	0.003149	0.08116	0.07822	EZR/ABCF2/CYTH4/TUBA3C/ARPC3/CYTH1/PAK2/TMBIM6/PAK3/MAPK13/MYO1F/RAB1A/ARHGEF12/NCK2/TUBB1/GNA12/CHUK/TUBB/MYO6/SRC/MYH9/CLDN15/CYFIP2	23
KEGG	hsa04659	Th17 cell differentiation	15/515	108/8135	0.003162	0.08116	0.07822	IL23R/JAK1/STAT5A/LCK/GATA3/STAT5B/MAPK13/ZAP70/IL4R/HLA-DRA/RORC/HLA-DPB1/AHR/CHUK/IL27RA	15
KEGG	hsa05010	Alzheimer disease	38/515	384/8135	0.003774	0.08942	0.08618	TUBA3C/NDUFB5/DVL3/SDHB/KLC1/NDUFB8/PSMA6/RAF1/PSMA2/KIF5C/UQCRC2/NDUFA12/DVL1/COX7A2L/PSMA4/VDAC2/COX7B/AXIN2/TUBB1/NDUFC2/NDUFV2/PSMB5/NDUFB3/SLC39A8/CHUK/TUBB/NDUFV1/GNAQ/CALM2/NDUFB1/GRIN2A/UQCRHL/UQCRFS1/NDUFA13/PSMB1/MAP2K7/NDUFAB1/CSNK1E	38
KEGG	hsa04932	Non-alcoholic fatty liver disease	19/515	155/8135	0.004094	0.09006	0.0868	NDUFB5/SDHB/NDUFB8/MAPK13/PRKAG2/UQCRC2/NDUFA12/COX7A2L/COX7B/MLXIP/NDUFC2/NDUFV2/NDUFB3/NDUFV1/NDUFB1/UQCRHL/UQCRFS1/NDUFA13/NDUFAB1	19
KEGG	hsa04658	Th1 and Th2 cell differentiation	13/515	92/8135	0.005009	0.1029	0.09913	JAK1/STAT5A/LCK/GATA3/STAT5B/MAPK13/ZAP70/IL4R/HLA-DRA/HLA-DPB1/CHUK/MAML2/MAF	13
KEGG	hsa04714	Thermogenesis	25/515	232/8135	0.006133	0.1181	0.1138	SMARCA4/NDUFB5/SDHB/NDUFB8/MAPK13/COX19/PRKAG2/UQCRC2/NDUFA12/COX7A2L/SMARCC1/COX7B/SMARCC2/PLIN1/NDUFC2/NDUFV2/NDUFB3/GNAS/NDUFV1/NDUFB1/UQCRHL/UQCRFS1/NDUFA13/MGLL/NDUFAB1	25
KEGG	hsa03022	Basal transcription factors	8/515	45/8135	0.006582	0.1192	0.1149	TAF3/GTF2B/GTF2F1/CCNH/TAF5L/GTF2A2/GTF2E2/TAF9	8
KEGG	hsa03420	Nucleotide excision repair	8/515	47/8135	0.008596	0.1471	0.1418	XPC/RPA4/POLD1/POLE4/CCNH/DDB1/POLE/ERCC8	8
KEGG	hsa00604	Glycosphingolipid biosynthesis - ganglio series	4/515	15/8135	0.01237	0.1995	0.1922	ST3GAL2/ST3GAL5/ST6GALNAC6/HEXB	4
KEGG	hsa03060	Protein export	5/515	23/8135	0.01295	0.1995	0.1922	SEC61B/SEC61G/SRP19/SPCS3/SEC11A	5
KEGG	hsa04660	T cell receptor signaling pathway	13/515	104/8135	0.01378	0.2021	0.1948	LCK/PAK2/PAK3/MAPK13/RAF1/CARD11/ZAP70/NCK2/CD40LG/CHUK/MAP3K14/GRAP2/MAP2K7	13
KEGG	hsa04630	JAK-STAT signaling pathway	17/515	162/8135	0.02713	0.3798	0.366	IL23R/SOCS6/JAK1/IL15/MCL1/STAT5A/CCND2/STAT5B/RAF1/CREBBP/OSMR/PIAS4/IL4R/IFNA8/PDGFA/IFNW1/IL27RA	17
KEGG	hsa05415	Diabetic cardiomyopathy	20/515	203/8135	0.03201	0.4286	0.4131	NDUFB5/SDHB/NDUFB8/MAPK13/UQCRC2/NDUFA12/COX7A2L/VDAC2/COX7B/NDUFC2/NDUFV2/NDUFB3/NDUFV1/NDUFB1/UQCRHL/UQCRFS1/RAC2/NDUFA13/PDHA1/NDUFAB1	20
KEGG	hsa04120	Ubiquitin mediated proteolysis	15/515	142/8135	0.03466	0.4449	0.4287	UBE2Z/CBL/UBE2D3/PIAS4/ANAPC5/UBA2/UBE2E1/UBE2E2/UBE2J2/UBE2G2/RCHY1/UBE2O/DDB1/CBLC/ERCC8	15
KEGG	hsa04742	Taste transduction	10/515	86/8135	0.04431	0.5326	0.5133	PDE1A/HTR3E/TAS2R8/SCNN1B/GABRA2/SCNN1G/HTR1A/TAS2R45/SCN3A/HCN4	10
KEGG	hsa03040	Spliceosome	15/515	147/8135	0.04496	0.5326	0.5133	SNRPD1/DHX16/SNRNP27/SF3B3/SART1/ACIN1/PHF5A/PRPF6/LSM6/SF3B2/DHX38/RBM17/PRPF8/HSPA1L/DDX23	15
KEGG	hsa05418	Fluid shear stress and atherosclerosis	14/515	139/8135	0.05637	0.643	0.6197	ASS1/SUMO1/MGST1/MAPK13/MGST2/PIAS4/SUMO2/CHUK/PDGFA/SRC/CALM2/RAC2/GSTO1/MAP2K7	14
KEGG	hsa04064	NF-kappa B signaling pathway	11/515	104/8135	0.0639	0.6735	0.6491	CCL13/LCK/LTB/LY96/CARD11/ZAP70/PIAS4/CD40LG/CHUK/TNFSF14/MAP3K14	11
KEGG	hsa03050	Proteasome	6/515	46/8135	0.06826	0.6735	0.6491	PSMA6/PSMA2/POMP/PSMA4/PSMB5/PSMB1	6
KEGG	hsa05323	Rheumatoid arthritis	10/515	93/8135	0.06867	0.6735	0.6491	ITGAL/IL15/LTB/ATP6V1G3/HLA-DRA/HLA-DPB1/CD86/ATP6V0E1/PTH/ATP6V1F	10
KEGG	hsa04530	Tight junction	16/515	169/8135	0.06869	0.6735	0.6491	EZR/RAPGEF2/TUBA3C/ARPC3/SCRIB/CD1D/LLGL2/ACTN1/PRKAG2/JAM3/TIAM1/SRC/MYH9/CLDN15/CD1B/MAP2K7	16
KEGG	hsa04015	Rap1 signaling pathway	19/515	210/8135	0.07277	0.6735	0.6491	ITGAL/RAPGEF2/EVL/RASGRP2/PRKD2/RASSF5/MAPK13/RAF1/PGF/TIAM1/GNAS/PDGFA/GNAQ/SRC/CALM2/MRAS/GRIN2A/RAC2/TLN1	19
KEGG	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	8/515	70/8135	0.07352	0.6735	0.6491	ATP6V1G3/MAPK13/JAM3/CHUK/SRC/ATP6V0E1/MAP3K14/ATP6V1F	8
KEGG	hsa03030	DNA replication	5/515	36/8135	0.07434	0.6735	0.6491	RPA4/POLD1/POLE4/POLA2/POLE	5
KEGG	hsa03013	Nucleocytoplasmic transport	11/515	108/8135	0.07917	0.6967	0.6714	NUP62/TNPO3/SUMO1/NUP210/ACIN1/DDX19A/THOC7/XPO6/SUMO2/NUP214/NUP188	11
KEGG	hsa05416	Viral myocarditis	7/515	60/8135	0.08322	0.7118	0.6861	ITGAL/HLA-DRA/CD40LG/HLA-DPB1/CD86/SGCB/RAC2	7
KEGG	hsa04672	Intestinal immune network for IgA production	6/515	49/8135	0.08719	0.7118	0.6861	IL15/HLA-DRA/CD40LG/HLA-DPB1/CD86/MAP3K14	6
KEGG	hsa04012	ErbB signaling pathway	9/515	85/8135	0.08783	0.7118	0.6861	STAT5A/PAK2/STAT5B/CBL/PAK3/RAF1/NCK2/SRC/MAP2K7	9
KEGG	hsa05110	Vibrio cholerae infection	6/515	50/8135	0.09408	0.7315	0.705	ATP6V1G3/SEC61B/SEC61G/GNAS/ATP6V0E1/ATP6V1F	6
KEGG	hsa05203	Viral carcinogenesis	18/515	204/8135	0.095	0.7315	0.705	CHD4/JAK1/STAT5A/SCRIB/CCND2/STAT5B/ACTN1/CREBBP/GTF2B/HDAC11/GTF2A2/HDAC10/HDAC7/SRC/CCR3/CDK6/GTF2E2/DDB1	18
KEGG	hsa04540	Gap junction	9/515	88/8135	0.1036	0.772	0.7441	TUBA3C/GJD2/RAF1/TUBB1/GNAS/TUBB/PDGFA/GNAQ/SRC	9
KEGG	hsa04670	Leukocyte transendothelial migration	11/515	114/8135	0.106	0.772	0.7441	EZR/ITGAL/VCL/CD99L2/RASSF5/MAPK13/ACTN1/JAM3/MYL7/RAC2/CLDN15	11
KEGG	hsa04392	Hippo signaling pathway - multiple species	4/515	29/8135	0.1078	0.772	0.7441	FRMD6/WWTR1/YAP1/CSNK1E	4
KEGG	hsa05321	Inflammatory bowel disease	7/515	65/8135	0.1153	0.7934	0.7646	IL23R/GATA3/IL4R/HLA-DRA/RORC/HLA-DPB1/MAF	7
KEGG	hsa04961	Endocrine and other factor-regulated calcium reabsorption	6/515	53/8135	0.1164	0.7934	0.7646	SLC8A3/GNAS/GNAQ/PTH/ATP1A1/DNM2	6
KEGG	hsa00020	Citrate cycle (TCA cycle)	4/515	30/8135	0.1185	0.7934	0.7646	OGDH/SDHB/MDH1/PDHA1	4
KEGG	hsa04625	C-type lectin receptor signaling pathway	10/515	104/8135	0.1215	0.796	0.7672	MAPK13/RAF1/ARHGEF12/CARD9/CHUK/SRC/CALM2/MRAS/MAP3K14/CLEC4D	10
KEGG	hsa03018	RNA degradation	8/515	79/8135	0.1255	0.8055	0.7764	DIS3L/LSM6/ENO2/TOB2/EXOSC10/ENO3/C1D/PABPC1L	8
KEGG	hsa04923	Regulation of lipolysis in adipocytes	6/515	56/8135	0.1412	0.8824	0.8504	PLIN1/GNAS/AQP7/FABP4/MGLL/PTGS1	6
KEGG	hsa04962	Vasopressin-regulated water reabsorption	5/515	44/8135	0.1432	0.8824	0.8504	DYNC1H1/STX4/DCTN6/GNAS/DCTN4	5
KEGG	hsa04514	Cell adhesion molecules	13/515	149/8135	0.1489	0.8901	0.8578	ITGAL/CD99L2/CD58/VCAN/GLG1/JAM3/HLA-DRA/CD40LG/HLA-DPB1/CD86/LRRC4/SELPLG/CLDN15	13
KEGG	hsa04917	Prolactin signaling pathway	7/515	70/8135	0.1528	0.8901	0.8578	SOCS6/STAT5A/CCND2/STAT5B/MAPK13/RAF1/SRC	7
KEGG	hsa03410	Base excision repair	4/515	33/8135	0.1532	0.8901	0.8578	MBD4/POLD1/POLE4/POLE	4
KEGG	hsa00564	Glycerophospholipid metabolism	9/515	98/8135	0.1667	0.9148	0.8817	DGKD/PCYT1A/DGKH/CDS1/CHPT1/LYPLA2/LPCAT1/ETNK1/PTDSS2	9
KEGG	hsa05231	Choline metabolism in cancer	9/515	98/8135	0.1667	0.9148	0.8817	DGKD/PCYT1A/DGKH/RAF1/CHPT1/PDGFA/PIP5K1B/RAC2/SLC44A2	9
KEGG	hsa04330	Notch signaling pathway	6/515	59/8135	0.1681	0.9148	0.8817	DVL3/MFNG/CREBBP/DVL1/CTBP1/MAML2	6
KEGG	hsa04137	Mitophagy - animal	7/515	72/8135	0.1693	0.9148	0.8817	OPTN/RHOT2/SRC/MRAS/ATG5/TBC1D15/BCL2L13	7
KEGG	hsa04934	Cushing syndrome	13/515	155/8135	0.1824	0.9654	0.9304	WDR5/DVL3/CDKN2C/MRAP/DVL1/AXIN2/CYP11B1/AHR/GNAS/GNAQ/ARMC5/CDK6/KCNA4	13
KEGG	hsa04726	Serotonergic synapse	10/515	115/8135	0.1914	0.9654	0.9304	HTR3E/RAF1/GABRB3/GNG5/GNAS/GNB1/GNAQ/KCNN2/HTR1A/PTGS1	10
KEGG	hsa05017	Spinocerebellar ataxia	12/515	143/8135	0.194	0.9654	0.9304	PSMA6/PSMA2/GTF2B/PSMA4/VDAC2/ATXN10/PSMB5/GNAQ/GRIN2A/ATXN3/PSMB1/TRPC3	12
KEGG	hsa04141	Protein processing in endoplasmic reticulum	14/515	171/8135	0.1942	0.9654	0.9304	DNAJC5B/UBE2D3/MAN1B1/SAR1A/SEC61B/VCP/SEC61G/LMAN1L/UBE2J2/UBE2G2/HSPA1L/ATXN3/DNAJC3/MAP2K7	14
KEGG	hsa04390	Hippo signaling pathway	13/515	157/8135	0.1943	0.9654	0.9304	SCRIB/DVL3/LLGL2/CCND2/SNAI2/DVL1/GDF6/ID2/FRMD6/AXIN2/WWTR1/YAP1/CSNK1E	13
KEGG	hsa05220	Chronic myeloid leukemia	7/515	76/8135	0.2044	0.9929	0.9569	STAT5A/STAT5B/CBL/RAF1/CHUK/CTBP1/CDK6	7
KEGG	hsa04014	Ras signaling pathway	18/515	232/8135	0.2161	0.9929	0.9569	RASGRP2/PAK2/RASSF5/RALBP1/PAK3/RAF1/GNG5/RASAL3/ZAP70/PGF/TIAM1/CHUK/GNB1/PDGFA/CALM2/MRAS/GRIN2A/RAC2	18
KEGG	hsa05330	Allograft rejection	4/515	38/8135	0.2179	0.9929	0.9569	HLA-DRA/CD40LG/HLA-DPB1/CD86	4
KEGG	hsa00980	Metabolism of xenobiotics by cytochrome P450	7/515	78/8135	0.2229	0.9929	0.9569	MGST1/MGST2/AKR7A2/AKR7A3/UGT2B7/GSTO1/GSTK1	7
KEGG	hsa04721	Synaptic vesicle cycle	7/515	78/8135	0.2229	0.9929	0.9569	ATP6V1G3/STXBP1/ATP6V0E1/SLC17A6/SLC6A5/ATP6V1F/DNM2	7
KEGG	hsa00513	Various types of N-glycan biosynthesis	4/515	39/8135	0.2317	0.9929	0.9569	ALG1/MAN1B1/ALG13/HEXB	4
KEGG	hsa04144	Endocytosis	19/515	251/8135	0.24	0.9929	0.9569	CYTH4/ARPC3/CYTH1/CBL/ARF4/CHMP2B/KIF5C/VPS36/SNX3/RAB11FIP4/VPS29/RAB11FIP5/CHMP5/SRC/PIP5K1B/GRK4/HSPA1L/CBLC/DNM2	19
KEGG	hsa05166	Human T-cell leukemia virus 1 infection	17/515	222/8135	0.2406	0.9929	0.9569	ITGAL/JAK1/IL15/STAT5A/LCK/CCND2/STAT5B/CDKN2C/CREBBP/VDAC2/HLA-DRA/ANAPC5/HLA-DPB1/TRRAP/CHUK/MAP3K14/TLN1	17
KEGG	hsa04966	Collecting duct acid secretion	3/515	27/8135	0.2424	0.9929	0.9569	ATP6V1G3/ATP6V0E1/ATP6V1F	3
KEGG	hsa05320	Autoimmune thyroid disease	5/515	53/8135	0.2431	0.9929	0.9569	HLA-DRA/CD40LG/IFNA8/HLA-DPB1/CD86	5
KEGG	hsa00603	Glycosphingolipid biosynthesis - globo and isoglobo series	2/515	15/8135	0.2449	0.9929	0.9569	ST3GAL2/HEXB	2
KEGG	hsa05033	Nicotine addiction	4/515	40/8135	0.2456	0.9929	0.9569	GABRB3/GABRA2/SLC17A6/GRIN2A	4
KEGG	hsa05135	Yersinia infection	11/515	137/8135	0.2496	0.9929	0.9569	LCK/ARPC3/MAPK13/ZAP70/ARHGEF12/CHUK/GNAQ/SRC/PIP5K1B/RAC2/MAP2K7	11
KEGG	hsa05163	Human cytomegalovirus infection	17/515	225/8135	0.258	0.9929	0.9569	JAK1/AKAP13/MAPK13/RAF1/GNG5/ARHGEF12/IFNA8/GNA12/GNAS/CHUK/GNB1/GNAQ/SRC/CALM2/CCR3/CDK6/RAC2	17
KEGG	hsa04611	Platelet activation	10/515	124/8135	0.2591	0.9929	0.9569	RASGRP2/GP5/MAPK13/ARHGEF12/GNAS/GNAQ/SRC/GP6/TLN1/PTGS1	10
KEGG	hsa03440	Homologous recombination	4/515	41/8135	0.2598	0.9929	0.9569	RPA4/POLD1/SYCP3/MUS81	4
KEGG	hsa04216	Ferroptosis	4/515	41/8135	0.2598	0.9929	0.9569	ATG7/VDAC2/SLC39A8/ATG5	4
KEGG	hsa03015	mRNA surveillance pathway	8/515	97/8135	0.2707	0.9929	0.9569	ACIN1/DDX19A/CPSF1/WDR82/CSTF2T/DAZAP1/CLP1/PABPC1L	8
KEGG	hsa04340	Hedgehog signaling pathway	5/515	56/8135	0.2798	0.9929	0.9569	MEGF8/PTCH1/CCND2/CSNK1G2/CSNK1E	5
KEGG	hsa04622	RIG-I-like receptor signaling pathway	6/515	70/8135	0.2817	0.9929	0.9569	MAPK13/ATG12/IFNA8/CHUK/ATG5/IFNW1	6
KEGG	hsa04640	Hematopoietic cell lineage	8/515	99/8135	0.2893	0.9929	0.9569	CD1D/GP5/IL4R/HLA-DRA/HLA-DPB1/CD38/MS4A1/CD1B	8
KEGG	hsa04510	Focal adhesion	15/515	201/8135	0.2911	0.9929	0.9569	DIAPH1/VCL/PAK2/CCND2/PAK3/RAF1/ACTN1/MYL7/PGF/PDGFA/SRC/PIP5K1B/RAC2/FLNB/TLN1	15
KEGG	hsa05134	Legionellosis	5/515	57/8135	0.2923	0.9929	0.9569	SAR1A/RAB1A/VCP/HSPA1L/BCL2L13	5
KEGG	hsa04520	Adherens junction	6/515	71/8135	0.2928	0.9929	0.9569	VCL/SNAI2/ACTN1/CREBBP/SRC/RAC2	6
KEGG	hsa00120	Primary bile acid biosynthesis	2/515	17/8135	0.2931	0.9929	0.9569	CH25H/ACOT8	2
KEGG	hsa00982	Drug metabolism - cytochrome P450	6/515	72/8135	0.304	0.9929	0.9569	MGST1/MGST2/FMO5/UGT2B7/GSTO1/GSTK1	6
KEGG	hsa05223	Non-small cell lung cancer	6/515	72/8135	0.304	0.9929	0.9569	STAT5A/RASSF5/STAT5B/RAF1/KIF5C/CDK6	6
KEGG	hsa04260	Cardiac muscle contraction	7/515	87/8135	0.3121	0.9929	0.9569	SLC8A3/UQCRC2/COX7A2L/COX7B/UQCRHL/UQCRFS1/ATP1A1	7
KEGG	hsa04710	Circadian rhythm	3/515	31/8135	0.3127	0.9929	0.9569	PRKAG2/RORC/CSNK1E	3
KEGG	hsa05310	Asthma	3/515	31/8135	0.3127	0.9929	0.9569	HLA-DRA/CD40LG/HLA-DPB1	3
KEGG	hsa00511	Other glycan degradation	2/515	18/8135	0.317	0.9929	0.9569	ENGASE/HEXB	2
KEGG	hsa04730	Long-term depression	5/515	60/8135	0.3303	0.9929	0.9569	RAF1/GNAZ/GNA12/GNAS/GNAQ	5
KEGG	hsa04978	Mineral absorption	5/515	60/8135	0.3303	0.9929	0.9569	SLC8A3/SLC6A19/CYBRD1/ATP1A1/MT1X	5
KEGG	hsa04136	Autophagy - other	3/515	32/8135	0.3304	0.9929	0.9569	ATG7/ATG12/ATG5	3
KEGG	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	7/515	89/8135	0.3328	0.9929	0.9569	JAK1/LCK/MAPK13/RAF1/ZAP70/CHUK/BATF	7
KEGG	hsa04072	Phospholipase D signaling pathway	11/515	148/8135	0.3352	0.9929	0.9569	CYTH4/DGKD/CYTH1/DGKH/RAF1/GNA12/GNAS/PDGFA/MRAS/PIP5K1B/DNM2	11
KEGG	hsa00531	Glycosaminoglycan degradation	2/515	19/8135	0.3408	0.9929	0.9569	HPSE2/HEXB	2
KEGG	hsa05167	Kaposi sarcoma-associated herpesvirus infection	14/515	194/8135	0.3448	0.9929	0.9569	JAK1/MAPK13/RAF1/CREBBP/GNG5/IFNA8/CHUK/CD86/GNB1/SRC/CALM2/CCR3/CDK6/MAP2K7	14
KEGG	hsa04130	SNARE interactions in vesicular transport	3/515	33/8135	0.3482	0.9929	0.9569	STX4/VAMP7/VAMP5	3
KEGG	hsa05212	Pancreatic cancer	6/515	76/8135	0.3496	0.9929	0.9569	JAK1/RALBP1/RAF1/CHUK/CDK6/RAC2	6
KEGG	hsa05032	Morphine addiction	7/515	91/8135	0.3537	0.9929	0.9569	PDE1A/GABRB3/GNG5/GNAS/GNB1/GABRA2/GRK4	7
KEGG	hsa04928	Parathyroid hormone synthesis, secretion and action	8/515	106/8135	0.3564	0.9929	0.9569	AKAP13/GATA3/RAF1/MMP15/GNA12/GNAS/GNAQ/PTH	8
KEGG	hsa04919	Thyroid hormone signaling pathway	9/515	121/8135	0.3581	0.9929	0.9569	MED16/MED24/RAF1/CREBBP/MED30/MED4/SLC16A10/SRC/ATP1A1	9
KEGG	hsa05100	Bacterial invasion of epithelial cells	6/515	77/8135	0.3611	0.9929	0.9569	ARHGAP10/ARPC3/VCL/CBL/SRC/DNM2	6
KEGG	hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	2/515	20/8135	0.3643	0.9929	0.9569	CSGALNACT2/B3GALT6	2
KEGG	hsa00670	One carbon pool by folate	2/515	20/8135	0.3643	0.9929	0.9569	MTHFD2/TYMS	2
KEGG	hsa04145	Phagosome	11/515	152/8135	0.3677	0.9929	0.9569	TUBA3C/DYNC1H1/ATP6V1G3/SEC61B/HLA-DRA/HLA-DPB1/TUBB1/SEC61G/TUBB/ATP6V0E1/ATP6V1F	11
KEGG	hsa04912	GnRH signaling pathway	7/515	93/8135	0.3748	0.9929	0.9569	MAPK13/RAF1/GNAS/GNAQ/SRC/CALM2/MAP2K7	7
KEGG	hsa01240	Biosynthesis of cofactors	11/515	153/8135	0.3759	0.9929	0.9569	NME6/PPCS/CAD/PDXK/ALPL/MMAB/PANK3/EARS2/MTHFD2/KYNU/UGT2B7	11
KEGG	hsa04921	Oxytocin signaling pathway	11/515	154/8135	0.3841	0.9929	0.9569	EEF2K/CAMK1D/EEF2/RAF1/PRKAG2/GNAS/GNAQ/SRC/CD38/CALM2/CAMKK2	11
KEGG	hsa05162	Measles	10/515	139/8135	0.385	0.9929	0.9569	JAK1/STAT5A/CCND2/STAT5B/IFNA8/RAB9A/CHUK/CDK6/RCHY1/HSPA1L	10
KEGG	hsa00770	Pantothenate and CoA biosynthesis	2/515	21/8135	0.3874	0.9929	0.9569	PPCS/PANK3	2
KEGG	hsa00510	N-Glycan biosynthesis	4/515	50/8135	0.391	0.9929	0.9569	ALG1/MAN1B1/ALG13/DPM1	4
KEGG	hsa04927	Cortisol synthesis and secretion	5/515	65/8135	0.3943	0.9929	0.9569	MRAP/CYP11B1/GNAS/GNAQ/KCNA4	5
KEGG	hsa00512	Mucin type O-glycan biosynthesis	3/515	36/8135	0.4009	0.9929	0.9569	ST3GAL2/GALNT6/ST6GALNAC1	3
KEGG	hsa00270	Cysteine and methionine metabolism	4/515	51/8135	0.4056	0.9929	0.9569	MRI1/DNMT1/MDH1/DNMT3A	4
KEGG	hsa05145	Toxoplasmosis	8/515	112/8135	0.4152	0.9929	0.9569	JAK1/LY96/MAPK13/HLA-DRA/CD40LG/HLA-DPB1/CHUK/HSPA1L	8
KEGG	hsa04070	Phosphatidylinositol signaling system	7/515	97/8135	0.4171	0.9929	0.9569	DGKD/PPIP5K1/DGKH/CDS1/PPIP5K2/CALM2/PIP5K1B	7
KEGG	hsa04960	Aldosterone-regulated sodium reabsorption	3/515	37/8135	0.4182	0.9929	0.9569	SCNN1B/SCNN1G/ATP1A1	3
KEGG	hsa00010	Glycolysis / Gluconeogenesis	5/515	67/8135	0.4199	0.9929	0.9569	GALM/ENO2/GAPDHS/ENO3/PDHA1	5
KEGG	hsa04720	Long-term potentiation	5/515	67/8135	0.4199	0.9929	0.9569	RAF1/CREBBP/GNAQ/CALM2/GRIN2A	5
KEGG	hsa00600	Sphingolipid metabolism	4/515	52/8135	0.4201	0.9929	0.9569	CERK/SMPD1/HEXB/GALC	4
KEGG	hsa04613	Neutrophil extracellular trap formation	13/515	190/8135	0.4273	0.9929	0.9569	ITGAL/MAPK13/RAF1/ATG7/CLCN3/HDAC11/VDAC2/C5/HDAC10/HDAC7/SRC/SELPLG/RAC2	13
KEGG	hsa04925	Aldosterone synthesis and secretion	7/515	98/8135	0.4276	0.9929	0.9569	DAGLB/PRKD2/CAMK1D/GNAS/GNAQ/CALM2/ATP1A1	7
KEGG	hsa00515	Mannose type O-glycan biosynthesis	2/515	23/8135	0.4326	0.9929	0.9569	B3GAT2/FKTN	2
KEGG	hsa03430	Mismatch repair	2/515	23/8135	0.4326	0.9929	0.9569	RPA4/POLD1	2
KEGG	hsa04964	Proximal tubule bicarbonate reclamation	2/515	23/8135	0.4326	0.9929	0.9569	MDH1/ATP1A1	2
KEGG	hsa05340	Primary immunodeficiency	3/515	38/8135	0.4354	0.9929	0.9569	LCK/ZAP70/CD40LG	3
KEGG	hsa04062	Chemokine signaling pathway	13/515	192/8135	0.4424	0.9929	0.9569	CCL13/RASGRP2/STAT5B/RAF1/GNG5/TIAM1/CHUK/GNB1/GNAQ/SRC/CCR3/GRK4/RAC2	13
KEGG	hsa05204	Chemical carcinogenesis - DNA adducts	5/515	69/8135	0.4452	0.9929	0.9569	MGST1/MGST2/UGT2B7/GSTO1/GSTK1	5
KEGG	hsa05211	Renal cell carcinoma	5/515	69/8135	0.4452	0.9929	0.9569	PAK2/PAK3/RAF1/EGLN3/CREBBP	5
KEGG	hsa05161	Hepatitis B	11/515	162/8135	0.4502	0.9929	0.9569	JAK1/STAT5A/STAT5B/MAPK13/RAF1/CREBBP/IFNA8/CHUK/SRC/DDB1/MAP2K7	11
KEGG	hsa04142	Lysosome	9/515	132/8135	0.459	0.9929	0.9569	AP3D1/LAPTM4A/NAGPA/LGMN/ENTPD4/SMPD1/CD63/HEXB/GALC	9
KEGG	hsa04916	Melanogenesis	7/515	101/8135	0.4591	0.9929	0.9569	DVL3/RAF1/CREBBP/DVL1/GNAS/GNAQ/CALM2	7
KEGG	hsa05170	Human immunodeficiency virus 1 infection	14/515	212/8135	0.4752	0.9929	0.9569	PAK2/TNFRSF1B/PAK3/MAPK13/RAF1/GNG5/IFNA8/CHUK/GNB1/GNAQ/CALM2/RAC2/DDB1/MAP2K7	14
KEGG	hsa04360	Axon guidance	12/515	182/8135	0.4854	0.9929	0.9569	PAK2/PTCH1/PAK3/RAF1/ARHGEF12/NCK2/SEMA4C/SRC/LRRC4/RAC2/SSH1/TRPC3	12
KEGG	hsa04310	Wnt signaling pathway	11/515	167/8135	0.4911	0.9929	0.9569	GPC4/DVL3/CCND2/CREBBP/DVL1/LGR5/AXIN2/CTBP1/RAC2/PRICKLE1/CSNK1E	11
KEGG	hsa04976	Bile secretion	6/515	89/8135	0.498	0.9929	0.9569	NR0B2/SCTR/GNAS/KCNN2/UGT2B7/ATP1A1	6
KEGG	hsa05225	Hepatocellular carcinoma	11/515	168/8135	0.4993	0.9929	0.9569	SMARCA4/MGST1/DVL3/RAF1/MGST2/DVL1/SMARCC1/SMARCC2/AXIN2/CDK6/GSTO1	11
KEGG	hsa05131	Shigellosis	16/515	247/8135	0.4999	0.9929	0.9569	CYTH4/ARPC3/DIAPH1/CYTH1/VCL/MAPK13/ACTN1/UBE2D3/ATG12/FNBP1L/MYL7/CHUK/SRC/ATG5/CBX3/TLN1	16
KEGG	hsa05332	Graft-versus-host disease	3/515	42/8135	0.502	0.9929	0.9569	HLA-DRA/HLA-DPB1/CD86	3
KEGG	hsa00240	Pyrimidine metabolism	4/515	58/8135	0.505	0.9929	0.9569	NME6/CAD/ENTPD4/TYMS	4
KEGG	hsa00480	Glutathione metabolism	4/515	58/8135	0.505	0.9929	0.9569	MGST1/MGST2/GSTO1/GSTK1	4
KEGG	hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	2/515	27/8135	0.5172	0.9929	0.9569	ST3GAL4/FUT7	2
KEGG	hsa00860	Porphyrin metabolism	3/515	43/8135	0.518	0.9929	0.9569	MMAB/EARS2/UGT2B7	3
KEGG	hsa04940	Type I diabetes mellitus	3/515	43/8135	0.518	0.9929	0.9569	HLA-DRA/HLA-DPB1/CD86	3
KEGG	hsa04370	VEGF signaling pathway	4/515	59/8135	0.5187	0.9929	0.9569	MAPK13/RAF1/SRC/RAC2	4
KEGG	hsa04918	Thyroid hormone synthesis	5/515	75/8135	0.5193	0.9929	0.9569	TTF1/ALB/GNAS/GNAQ/ATP1A1	5
KEGG	hsa05214	Glioma	5/515	75/8135	0.5193	0.9929	0.9569	CAMK1D/RAF1/PDGFA/CALM2/CDK6	5
KEGG	hsa04922	Glucagon signaling pathway	7/515	107/8135	0.5207	0.9929	0.9569	CREBBP/PRKAG2/PYGB/GNAS/GNAQ/CALM2/PDHA1	7
KEGG	hsa04371	Apelin signaling pathway	9/515	139/8135	0.5221	0.9929	0.9569	SLC8A3/RAF1/GNG5/PRKAG2/PLIN1/GNB1/GNAQ/CALM2/MRAS	9
KEGG	hsa04218	Cellular senescence	10/515	156/8135	0.5311	0.9929	0.9569	LIN54/RASSF5/CCND2/MAPK13/RAF1/VDAC2/HIPK1/CALM2/MRAS/CDK6	10
KEGG	hsa04971	Gastric acid secretion	5/515	76/8135	0.5313	0.9929	0.9569	EZR/GNAS/GNAQ/CALM2/ATP1A1	5
KEGG	hsa00650	Butanoate metabolism	2/515	28/8135	0.537	0.9929	0.9569	BDH1/ACSM2B	2
KEGG	hsa04936	Alcoholic liver disease	9/515	142/8135	0.5484	0.9929	0.9569	LY96/MAPK13/PRKAG2/IFNA8/C5/CHUK/MAP3K14/CAMKK2/MAP2K7	9
KEGG	hsa04110	Cell cycle	8/515	126/8135	0.5493	0.9929	0.9569	ORC4/CCND2/CDKN2C/SMC1A/CREBBP/ANAPC5/CCNH/CDK6	8
KEGG	hsa04744	Phototransduction	2/515	29/8135	0.5562	0.9929	0.9569	GNB1/CALM2	2
KEGG	hsa01521	EGFR tyrosine kinase inhibitor resistance	5/515	79/8135	0.5663	0.9929	0.9569	JAK1/RAF1/GAS6/PDGFA/SRC	5
KEGG	hsa04623	Cytosolic DNA-sensing pathway	4/515	63/8135	0.5713	0.9929	0.9569	POLR3A/IFNA8/CHUK/POLR3F	4
KEGG	hsa05217	Basal cell carcinoma	4/515	63/8135	0.5713	0.9929	0.9569	DVL3/PTCH1/DVL1/AXIN2	4
KEGG	hsa05150	Staphylococcus aureus infection	6/515	96/8135	0.5733	0.9929	0.9569	ITGAL/DEFB1/HLA-DRA/HLA-DPB1/C5/SELPLG	6
KEGG	hsa01523	Antifolate resistance	2/515	30/8135	0.5748	0.9929	0.9569	CHUK/TYMS	2
KEGG	hsa00983	Drug metabolism - other enzymes	5/515	80/8135	0.5777	0.9929	0.9569	NME6/MGST1/MGST2/UGT2B7/GSTO1	5
KEGG	hsa04713	Circadian entrainment	6/515	97/8135	0.5836	0.9929	0.9569	GNG5/GNAS/GNB1/GNAQ/CALM2/GRIN2A	6
KEGG	hsa05152	Tuberculosis	11/515	180/8135	0.5934	0.9929	0.9569	JAK1/MAPK13/RAF1/CREBBP/HLA-DRA/ARHGEF12/IFNA8/CARD9/HLA-DPB1/SRC/CALM2	11
KEGG	hsa04068	FoxO signaling pathway	8/515	131/8135	0.5942	0.9929	0.9569	CCND2/MAPK13/RAF1/CREBBP/PRKAG2/ATG12/CHUK/CSNK1E	8
KEGG	hsa01200	Carbon metabolism	7/515	115/8135	0.5984	0.9929	0.9569	H6PD/OGDH/SDHB/MDH1/ENO2/ENO3/PDHA1	7
KEGG	hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	1/515	14/8135	0.6	0.9929	0.9569	ST3GAL2	1
KEGG	hsa04728	Dopaminergic synapse	8/515	132/8135	0.603	0.9929	0.9569	MAPK13/KIF5C/GNG5/GNAS/GNB1/GNAQ/CALM2/GRIN2A	8
KEGG	hsa00565	Ether lipid metabolism	3/515	49/8135	0.6078	0.9929	0.9569	CHPT1/LPCAT1/TMEM189	3
KEGG	hsa04270	Vascular smooth muscle contraction	8/515	134/8135	0.6201	0.9929	0.9569	RAMP3/RAF1/ARHGEF12/GNA12/GNAS/GNAQ/CALM2/MYH9	8
KEGG	hsa05221	Acute myeloid leukemia	4/515	67/8135	0.6206	0.9929	0.9569	STAT5A/STAT5B/RAF1/CHUK	4
KEGG	hsa00730	Thiamine metabolism	1/515	15/8135	0.6254	0.9929	0.9569	ALPL	1
KEGG	hsa04664	Fc epsilon RI signaling pathway	4/515	68/8135	0.6324	0.9929	0.9569	MAPK13/RAF1/RAC2/MAP2K7	4
KEGG	hsa05146	Amoebiasis	6/515	102/8135	0.6331	0.9929	0.9569	VCL/CD1D/ACTN1/GNAS/GNAQ/CD1B	6
KEGG	hsa05169	Epstein-Barr virus infection	12/515	202/8135	0.6335	0.9929	0.9569	ITGAL/JAK1/CD58/CCND2/MAPK13/HLA-DRA/IFNA8/HLA-DPB1/CHUK/CDK6/MAP3K14/MAP2K7	12
KEGG	hsa04071	Sphingolipid signaling pathway	7/515	119/8135	0.6348	0.9929	0.9569	MAPK13/RAF1/GNA12/S1PR2/GNAQ/SMPD1/RAC2	7
KEGG	hsa04935	Growth hormone synthesis, secretion and action	7/515	119/8135	0.6348	0.9929	0.9569	STAT5A/STAT5B/MAPK13/RAF1/CREBBP/GNAS/GNAQ	7
KEGG	hsa05322	Systemic lupus erythematosus	8/515	136/8135	0.6369	0.9929	0.9569	SNRPD1/ACTN1/HLA-DRA/CD40LG/HLA-DPB1/C5/CD86/GRIN2A	8
KEGG	hsa04974	Protein digestion and absorption	6/515	103/8135	0.6425	0.9929	0.9569	SLC8A3/SLC7A9/SLC16A10/SLC6A19/KCNE3/ATP1A1	6
KEGG	hsa03020	RNA polymerase	2/515	34/8135	0.6437	0.9929	0.9569	POLR3A/POLR3F	2
KEGG	hsa04920	Adipocytokine signaling pathway	4/515	69/8135	0.6439	0.9929	0.9569	TNFRSF1B/PRKAG2/CHUK/CAMKK2	4
KEGG	hsa04924	Renin secretion	4/515	69/8135	0.6439	0.9929	0.9569	PDE1A/GNAS/GNAQ/CALM2	4
KEGG	hsa00430	Taurine and hypotaurine metabolism	1/515	16/8135	0.6491	0.9929	0.9569	FMO5	1
KEGG	hsa04620	Toll-like receptor signaling pathway	6/515	104/8135	0.6519	0.9929	0.9569	LY96/MAPK13/IFNA8/CHUK/CD86/MAP2K7	6
KEGG	hsa05205	Proteoglycans in cancer	12/515	205/8135	0.6538	0.9929	0.9569	EZR/HPSE2/PTCH1/CBL/MAPK13/RAF1/ARHGEF12/TIAM1/SRC/MRAS/CD63/FLNB	12
KEGG	hsa04727	GABAergic synapse	5/515	89/8135	0.6724	0.9929	0.9569	GABRB3/GNG5/GNB1/SRC/GABRA2	5
KEGG	hsa03460	Fanconi anemia pathway	3/515	54/8135	0.6736	0.9929	0.9569	RPA4/ATRIP/MUS81	3
KEGG	hsa00500	Starch and sucrose metabolism	2/515	36/8135	0.6747	0.9929	0.9569	PYGB/GYG1	2
KEGG	hsa04140	Autophagy - animal	8/515	141/8135	0.6769	0.9929	0.9569	RAF1/ATG7/RAB1A/ATG12/ZFYVE1/MRAS/ATG5/CAMKK2	8
KEGG	hsa04217	Necroptosis	9/515	159/8135	0.6843	0.9929	0.9569	JAK1/STAT5A/STAT5B/CHMP2B/PYGB/VDAC2/IFNA8/CHMP5/SMPD1	9
KEGG	hsa04115	p53 signaling pathway	4/515	73/8135	0.6875	0.9929	0.9569	CCND2/CDK6/CD82/RCHY1	4
KEGG	hsa00250	Alanine, aspartate and glutamate metabolism	2/515	37/8135	0.6893	0.9929	0.9569	ASS1/CAD	2
KEGG	hsa04060	Cytokine-cytokine receptor interaction	17/515	295/8135	0.6934	0.9929	0.9569	IL23R/CCL13/IL15/TNFRSF1B/LTB/CXCL17/GDF6/OSMR/IL4R/CD40LG/IFNA8/IL17RB/TNFRSF25/TNFSF14/CCR3/IFNW1/IL27RA	17
KEGG	hsa03008	Ribosome biogenesis in eukaryotes	6/515	109/8135	0.6962	0.9929	0.9569	UTP14A/PWP2/BMS1/NOP10/RRP7A/RBM28	6
KEGG	hsa05165	Human papillomavirus infection	19/515	331/8135	0.7069	0.9929	0.9569	CHD4/JAK1/SCRIB/DVL3/LLGL2/CCND2/MFNG/ATP6V1G3/RAF1/CREBBP/DVL1/IFNA8/AXIN2/GNAS/CHUK/ATP6V0E1/CDK6/MAML2/ATP6V1F	19
KEGG	hsa03320	PPAR signaling pathway	4/515	75/8135	0.7079	0.9929	0.9569	PLIN1/AQP7/FABP4/SLC27A6	4
KEGG	hsa04970	Salivary secretion	5/515	93/8135	0.7097	0.9929	0.9569	GNAS/GNAQ/CD38/CALM2/ATP1A1	5
KEGG	hsa04926	Relaxin signaling pathway	7/515	129/8135	0.7169	0.9929	0.9569	MAPK13/RAF1/GNG5/GNAS/GNB1/SRC/MAP2K7	7
KEGG	hsa05133	Pertussis	4/515	76/8135	0.7177	0.9929	0.9569	LY96/MAPK13/C5/CALM2	4
KEGG	hsa04668	TNF signaling pathway	6/515	112/8135	0.721	0.9929	0.9569	IL15/TNFRSF1B/MAPK13/CHUK/MAP3K14/MAP2K7	6
KEGG	hsa05140	Leishmaniasis	4/515	77/8135	0.7273	0.9929	0.9569	JAK1/MAPK13/HLA-DRA/HLA-DPB1	4
KEGG	hsa04612	Antigen processing and presentation	4/515	78/8135	0.7366	0.9929	0.9569	LGMN/HLA-DRA/HLA-DPB1/HSPA1L	4
KEGG	hsa04724	Glutamatergic synapse	6/515	114/8135	0.7367	0.9929	0.9569	GNG5/GNAS/GNB1/GNAQ/SLC17A6/GRIN2A	6
KEGG	hsa05219	Bladder cancer	2/515	41/8135	0.7426	0.9929	0.9569	RAF1/SRC	2
KEGG	hsa04666	Fc gamma R-mediated phagocytosis	5/515	97/8135	0.7439	0.9929	0.9569	ARPC3/RAF1/PIP5K1B/RAC2/DNM2	5
KEGG	hsa05215	Prostate cancer	5/515	97/8135	0.7439	0.9929	0.9569	RAF1/CREBBP/ERG/CHUK/PDGFA	5
KEGG	hsa00140	Steroid hormone biosynthesis	3/515	61/8135	0.7515	0.9929	0.9569	CYP11B1/DHRS11/UGT2B7	3
KEGG	hsa00561	Glycerolipid metabolism	3/515	61/8135	0.7515	0.9929	0.9569	DGKD/DGKH/MGLL	3
KEGG	hsa01522	Endocrine resistance	5/515	98/8135	0.752	0.9929	0.9569	CDKN2C/MAPK13/RAF1/GNAS/SRC	5
KEGG	hsa04750	Inflammatory mediator regulation of TRP channels	5/515	98/8135	0.752	0.9929	0.9569	MAPK13/GNAS/GNAQ/SRC/CALM2	5
KEGG	hsa05034	Alcoholism	10/515	187/8135	0.7546	0.9929	0.9569	RAF1/GNG5/HDAC11/GNAS/GNB1/HDAC10/HDAC7/CALM2/GRIN2A/CAMKK2	10
KEGG	hsa04213	Longevity regulating pathway - multiple species	3/515	62/8135	0.7613	0.9929	0.9569	PRKAG2/ATG5/HSPA1L	3
KEGG	hsa00220	Arginine biosynthesis	1/515	22/8135	0.7632	0.9929	0.9569	ASS1	1
KEGG	hsa00340	Histidine metabolism	1/515	22/8135	0.7632	0.9929	0.9569	HDC	1
KEGG	hsa05164	Influenza A	9/515	171/8135	0.7635	0.9929	0.9569	JAK1/RAF1/CREBBP/HLA-DRA/IFNA8/HLA-DPB1/CHUK/CDK6/DNAJC3	9
KEGG	hsa04210	Apoptosis	7/515	136/8135	0.7664	0.9929	0.9569	TUBA3C/MCL1/DFFA/RAF1/LMNB2/CHUK/MAP3K14	7
KEGG	hsa04146	Peroxisome	4/515	82/8135	0.7715	0.9929	0.9569	PEX2/PEX5/ACOT8/GSTK1	4
KEGG	hsa04662	B cell receptor signaling pathway	4/515	82/8135	0.7715	0.9929	0.9569	RAF1/CARD11/CHUK/RAC2	4
KEGG	hsa04010	MAPK signaling pathway	16/515	294/8135	0.7719	0.9929	0.9569	DUSP16/RAPGEF2/RASGRP2/PAK2/MAPK13/RAF1/PGF/GNA12/CHUK/PDGFA/MRAS/RAC2/HSPA1L/MAP3K14/FLNB/MAP2K7	16
KEGG	hsa04614	Renin-angiotensin system	1/515	23/8135	0.7783	0.9929	0.9569	MRGPRD	1
KEGG	hsa04929	GnRH secretion	3/515	64/8135	0.78	0.9929	0.9569	RAF1/GNAQ/KCNN2	3
KEGG	hsa04914	Progesterone-mediated oocyte maturation	5/515	102/8135	0.7823	0.9929	0.9569	MAPK13/RAF1/STK10/ANAPC5/SPDYE2	5
KEGG	hsa04972	Pancreatic secretion	5/515	102/8135	0.7823	0.9929	0.9569	SCTR/GNAS/GNAQ/CD38/ATP1A1	5
KEGG	hsa02010	ABC transporters	2/515	45/8135	0.7878	0.9929	0.9569	DEFB1/ABCA3	2
KEGG	hsa00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	1/515	24/8135	0.7923	0.9929	0.9569	B3GALT6	1
KEGG	hsa01232	Nucleotide metabolism	4/515	85/8135	0.7952	0.9929	0.9569	NME6/ENTPD4/DGUOK/TYMS	4
KEGG	hsa04911	Insulin secretion	4/515	86/8135	0.8026	0.9929	0.9569	GNAS/GNAQ/KCNN2/ATP1A1	4
KEGG	hsa00514	Other types of O-glycan biosynthesis	2/515	47/8135	0.8077	0.9929	0.9569	MFNG/GALNT6	2
KEGG	hsa00620	Pyruvate metabolism	2/515	47/8135	0.8077	0.9929	0.9569	MDH1/PDHA1	2
KEGG	hsa04550	Signaling pathways regulating pluripotency of stem cells	7/515	143/8135	0.8093	0.9929	0.9569	JAK1/DVL3/MAPK13/RAF1/DVL1/ID2/AXIN2	7
KEGG	hsa00830	Retinol metabolism	3/515	68/8135	0.8138	0.9929	0.9569	CYP2W1/UGT2B7/ALDH1A1	3
KEGG	hsa00563	Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	1/515	26/8135	0.8179	0.9929	0.9569	PIGF	1
KEGG	hsa00790	Folate biosynthesis	1/515	26/8135	0.8179	0.9929	0.9569	ALPL	1
KEGG	hsa05031	Amphetamine addiction	3/515	69/8135	0.8215	0.9929	0.9569	GNAS/CALM2/GRIN2A	3
KEGG	hsa00520	Amino sugar and nucleotide sugar metabolism	2/515	49/8135	0.8259	0.9929	0.9569	CYB5R4/HEXB	2
KEGG	hsa05030	Cocaine addiction	2/515	49/8135	0.8259	0.9929	0.9569	GNAS/GRIN2A	2
KEGG	hsa04066	HIF-1 signaling pathway	5/515	109/8135	0.8285	0.9929	0.9569	EGLN3/CREBBP/ENO2/ENO3/PDHA1	5
KEGG	hsa00230	Purine metabolism	6/515	128/8135	0.829	0.9929	0.9569	NME6/GUCY2C/PDE1A/ENTPD4/DGUOK/PDE9A	6
KEGG	hsa04380	Osteoclast differentiation	6/515	128/8135	0.829	0.9929	0.9569	JAK1/LCK/MAPK13/CHUK/MAP3K14/MAP2K7	6
KEGG	hsa00062	Fatty acid elongation	1/515	27/8135	0.8294	0.9929	0.9569	THEM5	1
KEGG	hsa04621	NOD-like receptor signaling pathway	9/515	184/8135	0.8323	0.9929	0.9569	JAK1/NLRP1/MAPK13/ATG12/VDAC2/IFNA8/CARD9/CHUK/ATG5	9
KEGG	hsa05144	Malaria	2/515	50/8135	0.8344	0.9929	0.9569	ITGAL/CD40LG	2
KEGG	hsa04024	cAMP signaling pathway	11/515	221/8135	0.8359	0.9929	0.9569	PTCH1/RAF1/CREBBP/TIAM1/GNAS/CALM2/GRIN2A/HTR1A/RAC2/HCN4/ATP1A1	11
KEGG	hsa04022	cGMP-PKG signaling pathway	8/515	167/8135	0.8384	0.9929	0.9569	SLC8A3/RAF1/VDAC2/GNA12/GNAQ/CALM2/ADRA2A/ATP1A1	8
KEGG	hsa05218	Melanoma	3/515	72/8135	0.8431	0.9929	0.9569	RAF1/PDGFA/CDK6	3
KEGG	hsa04650	Natural killer cell mediated cytotoxicity	6/515	131/8135	0.845	0.9929	0.9569	ITGAL/LCK/RAF1/ZAP70/IFNA8/RAC2	6
KEGG	hsa01524	Platinum drug resistance	3/515	73/8135	0.8497	0.9929	0.9569	MGST1/MGST2/GSTO1	3
KEGG	hsa04657	IL-17 signaling pathway	4/515	94/8135	0.8546	0.9929	0.9569	MAPK13/ANAPC5/IL17RB/CHUK	4
KEGG	hsa00030	Pentose phosphate pathway	1/515	30/8135	0.8599	0.9929	0.9569	H6PD	1
KEGG	hsa00053	Ascorbate and aldarate metabolism	1/515	30/8135	0.8599	0.9929	0.9569	UGT2B7	1
KEGG	hsa00630	Glyoxylate and dicarboxylate metabolism	1/515	30/8135	0.8599	0.9929	0.9569	MDH1	1
KEGG	hsa01230	Biosynthesis of amino acids	3/515	75/8135	0.8623	0.9929	0.9569	ASS1/ENO2/ENO3	3
KEGG	hsa00052	Galactose metabolism	1/515	31/8135	0.8688	0.9929	0.9569	GALM	1
KEGG	hsa05202	Transcriptional misregulation in cancer	9/515	193/8135	0.8701	0.9929	0.9569	FEV/CCND2/CDKN2C/SIX1/ID2/ERG/CD86/PDGFA/MAF	9
KEGG	hsa05207	Chemical carcinogenesis - receptor activation	10/515	212/8135	0.8718	0.9929	0.9569	STAT5A/MGST1/STAT5B/RAF1/MGST2/AHR/GNAS/SRC/UGT2B7/GSTO1	10
KEGG	hsa04915	Estrogen signaling pathway	6/515	138/8135	0.8777	0.9929	0.9569	RAF1/GNAS/GNAQ/SRC/CALM2/HSPA1L	6
KEGG	hsa04061	Viral protein interaction with cytokine and cytokine receptor	4/515	100/8135	0.8855	0.9929	0.9569	CCL13/TNFRSF1B/TNFSF14/CCR3	4
KEGG	hsa04933	AGE-RAGE signaling pathway in diabetic complications	4/515	100/8135	0.8855	0.9929	0.9569	STAT5A/DIAPH1/STAT5B/MAPK13	4
KEGG	hsa05213	Endometrial cancer	2/515	58/8135	0.89	0.9929	0.9569	RAF1/AXIN2	2
KEGG	hsa00040	Pentose and glucuronate interconversions	1/515	34/8135	0.8923	0.9929	0.9569	UGT2B7	1
KEGG	hsa05142	Chagas disease	4/515	102/8135	0.8945	0.9929	0.9569	MAPK13/GNAS/CHUK/GNAQ	4
KEGG	hsa04020	Calcium signaling pathway	11/515	240/8135	0.9017	0.9929	0.9569	SLC8A3/CAMK1D/PDE1A/VDAC2/CASQ1/GNAS/PDGFA/GNAQ/CD38/CALM2/GRIN2A	11
KEGG	hsa00760	Nicotinate and nicotinamide metabolism	1/515	36/8135	0.9055	0.9929	0.9569	CD38	1
KEGG	hsa05143	African trypanosomiasis	1/515	37/8135	0.9116	0.9929	0.9569	GNAQ	1
KEGG	hsa04610	Complement and coagulation cascades	3/515	85/8135	0.9123	0.9929	0.9569	C5/CFHR2/F12	3
KEGG	hsa00310	Lysine degradation	2/515	63/8135	0.9154	0.9929	0.9569	SETMAR/SETD1B	2
KEGG	hsa03250	Viral life cycle - HIV-1	2/515	63/8135	0.9154	0.9929	0.9569	TNPO3/CREBBP	2
KEGG	hsa05210	Colorectal cancer	3/515	86/8135	0.9163	0.9929	0.9569	RAF1/AXIN2/RAC2	3
KEGG	hsa04931	Insulin resistance	4/515	108/8135	0.9177	0.9929	0.9569	PRKAG2/PYGB/MLXIP/SLC27A6	4
KEGG	hsa04261	Adrenergic signaling in cardiomyocytes	6/515	150/8135	0.9202	0.9929	0.9569	SLC8A3/MAPK13/GNAS/GNAQ/CALM2/ATP1A1	6
KEGG	hsa04114	Oocyte meiosis	5/515	131/8135	0.9244	0.9929	0.9569	SMC1A/MAPK13/ANAPC5/CALM2/SPDYE2	5
KEGG	hsa04211	Longevity regulating pathway	3/515	89/8135	0.9272	0.9929	0.9569	PRKAG2/ATG5/CAMKK2	3
KEGG	hsa05410	Hypertrophic cardiomyopathy	3/515	90/8135	0.9306	0.9929	0.9569	SLC8A3/PRKAG2/SGCB	3
KEGG	hsa05417	Lipid and atherosclerosis	9/515	215/8135	0.934	0.9929	0.9569	LY96/MAPK13/CD40LG/IFNA8/CHUK/SRC/CALM2/HSPA1L/MAP2K7	9
KEGG	hsa04740	Olfactory transduction	21/515	440/8135	0.9354	0.9929	0.9569	SLC8A3/PDE1A/OR10S1/OR4K17/OR51I2/OR1N2/OR4C16/OR52N5/OR4C45/OR6S1/OR6P1/GNB1/OR5B2/OR1B1/OR6X1/CALM2/OR4S1/OR4E2/OR56A5/OR3A3/OR10G2	21
KEGG	hsa04150	mTOR signaling pathway	6/515	156/8135	0.9361	0.9929	0.9569	DVL3/ATP6V1G3/RAF1/DVL1/CHUK/ATP6V1F	6
KEGG	hsa00380	Tryptophan metabolism	1/515	42/8135	0.9363	0.9929	0.9569	KYNU	1
KEGG	hsa05222	Small cell lung cancer	3/515	92/8135	0.9368	0.9929	0.9569	CHUK/CDK6/CKS1B	3
KEGG	hsa05160	Hepatitis C	6/515	157/8135	0.9385	0.9929	0.9569	JAK1/RAF1/IFNA8/CHUK/CDK6/CLDN15	6
KEGG	hsa04975	Fat digestion and absorption	1/515	43/8135	0.9404	0.9929	0.9569	MTTP	1
KEGG	hsa04910	Insulin signaling pathway	5/515	137/8135	0.9405	0.9929	0.9569	CBL/RAF1/PRKAG2/PYGB/CALM2	5
KEGG	hsa05230	Central carbon metabolism in cancer	2/515	70/8135	0.9419	0.9929	0.9569	RAF1/PDHA1	2
KEGG	hsa04350	TGF-beta signaling pathway	3/515	94/8135	0.9426	0.9929	0.9569	CREBBP/GDF6/ID2	3
KEGG	hsa05414	Dilated cardiomyopathy	3/515	96/8135	0.9478	0.9929	0.9569	SLC8A3/GNAS/SGCB	3
KEGG	hsa04722	Neurotrophin signaling pathway	4/515	119/8135	0.9488	0.9929	0.9569	MAPK13/RAF1/CALM2/MAP2K7	4
KEGG	hsa04152	AMPK signaling pathway	4/515	120/8135	0.951	0.9929	0.9569	EEF2K/EEF2/PRKAG2/CAMKK2	4
KEGG	hsa04973	Carbohydrate digestion and absorption	1/515	47/8135	0.9542	0.9929	0.9569	ATP1A1	1
KEGG	hsa00280	Valine, leucine and isoleucine degradation	1/515	48/8135	0.9571	0.9929	0.9569	IVD	1
KEGG	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	2/515	77/8135	0.9603	0.9929	0.9569	SLC8A3/SGCB	2
KEGG	hsa05224	Breast cancer	5/515	147/8135	0.9605	0.9929	0.9569	DVL3/RAF1/DVL1/AXIN2/CDK6	5
KEGG	hsa04979	Cholesterol metabolism	1/515	50/8135	0.9624	0.9929	0.9569	VDAC2	1
KEGG	hsa00330	Arginine and proline metabolism	1/515	51/8135	0.9648	0.9929	0.9569	OAT	1
KEGG	hsa04913	Ovarian steroidogenesis	1/515	51/8135	0.9648	0.9929	0.9569	GNAS	1
KEGG	hsa03010	Ribosome	5/515	158/8135	0.9753	0.9929	0.9569	RSL24D1/MRPL33/MRPL10/RPS2/MRPS15	5
KEGG	hsa04725	Cholinergic synapse	3/515	113/8135	0.9775	0.9929	0.9569	GNG5/GNB1/GNAQ	3
KEGG	hsa04512	ECM-receptor interaction	2/515	88/8135	0.9785	0.9929	0.9569	GP5/GP6	2
KEGG	hsa00590	Arachidonic acid metabolism	1/515	61/8135	0.9818	0.9929	0.9569	PTGS1	1
KEGG	hsa05168	Herpes simplex virus 1 infection	21/515	495/8135	0.9846	0.9929	0.9569	ZNF841/JAK1/ZNF468/ZNF350/ZNF160/HLA-DRA/IFNA8/CARD9/HLA-DPB1/C5/CHUK/EIF2B1/TNFSF14/SRC/ZNF440/ZNF37A/ZNF562/ZNF705A/ZNF573/ZNF300/ZNF667	21
KEGG	hsa00970	Aminoacyl-tRNA biosynthesis	1/515	66/8135	0.9869	0.9929	0.9569	EARS2	1
KEGG	hsa05226	Gastric cancer	4/515	149/8135	0.9872	0.9929	0.9569	DVL3/RAF1/DVL1/AXIN2	4
KEGG	hsa05206	MicroRNAs in cancer	11/515	310/8135	0.99	0.9929	0.9569	EZR/MCL1/CCND2/RAF1/CREBBP/DNMT1/PDGFA/CDK6/SLC7A1/FOXP1/DNMT3A	11
KEGG	hsa04080	Neuroactive ligand-receptor interaction	13/515	353/8135	0.9906	0.9929	0.9569	TAAR8/GABRB3/HCRT/TAAR9/SCTR/C5/S1PR2/GRP/GABRA2/PTH/GRIN2A/HTR1A/ADRA2A	13
KEGG	hsa04151	PI3K-Akt signaling pathway	13/515	354/8135	0.9909	0.9929	0.9569	JAK1/MCL1/CCND2/RAF1/GNG5/OSMR/IL4R/IFNA8/PGF/CHUK/GNB1/PDGFA/CDK6	13
KEGG	hsa00562	Inositol phosphate metabolism	1/515	73/8135	0.9917	0.9929	0.9569	PIP5K1B	1
KEGG	hsa05171	Coronavirus disease - COVID-19	7/515	232/8135	0.9929	0.9929	0.9569	JAK1/MAPK13/RSL24D1/IFNA8/C5/CHUK/RPS2	7