ONTOLOGY	ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	qvalue	geneID	Count
KEGG	hsa05168	Herpes simplex virus 1 infection	25/215	495/8135	0.001302	0.3698	0.3698	ZNF10/ZIK1/FAS/ZNF91/ZNF439/HLA-DOA/CYCS/ZNF599/ZNF383/ZNF184/ZNF268/PIK3R3/ZNF682/ZNF658/ZNF548/ZNF611/IRAK1/ZNF528/ZNF562/IKBKE/ZNF429/ZNF786/ZNF441/ZNF331/C3	25
KEGG	hsa04115	p53 signaling pathway	6/215	73/8135	0.01242	0.8582	0.8582	FAS/CYCS/IGFBP3/GORAB/GADD45B/SIVA1	6
KEGG	hsa04936	Alcoholic liver disease	9/215	142/8135	0.01281	0.8582	0.8582	FAS/FOXO3/ADIPOQ/ADIPOR1/CD14/IRAK1/IKBKE/CYP2E1/C3	9
KEGG	hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	3/215	20/8135	0.01489	0.8582	0.8582	CSGALNACT1/CHST3/UST	3
KEGG	hsa05330	Allograft rejection	4/215	38/8135	0.01734	0.8582	0.8582	CD40/FAS/HLA-DOA/IL4	4
KEGG	hsa05213	Endometrial cancer	5/215	58/8135	0.01813	0.8582	0.8582	AXIN2/FOXO3/PIK3R3/GADD45B/EGF	5
KEGG	hsa05210	Colorectal cancer	6/215	86/8135	0.02593	0.8706	0.8706	AXIN2/CYCS/RPS6KB1/PIK3R3/GADD45B/EGF	6
KEGG	hsa04211	Longevity regulating pathway	6/215	89/8135	0.03006	0.8706	0.8706	FOXO3/ADIPOQ/RPS6KB1/ADCY8/PIK3R3/ADIPOR1	6
KEGG	hsa05131	Shigellosis	12/215	247/8135	0.03061	0.8706	0.8706	PLCD4/PLCZ1/CYCS/FOXO3/RPS6KB1/PIK3R3/PLCB2/CD14/UBE2V2/BNIP3/PIK3R4/C3	12
KEGG	hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	3/215	27/8135	0.0334	0.8706	0.8706	FUT2/GCNT2/ST3GAL4	3
KEGG	hsa04152	AMPK signaling pathway	7/215	120/8135	0.03946	0.8706	0.8706	STRADB/PPP2R3C/FOXO3/ADIPOQ/RPS6KB1/PIK3R3/ADIPOR1	7
KEGG	hsa04672	Intestinal immune network for IgA production	4/215	49/8135	0.03984	0.8706	0.8706	CD40/HLA-DOA/IL4/IL15RA	4
KEGG	hsa05310	Asthma	3/215	31/8135	0.04755	0.8706	0.8706	CD40/HLA-DOA/IL4	3
KEGG	hsa04060	Cytokine-cytokine receptor interaction	13/215	295/8135	0.04881	0.8706	0.8706	CD40/TNFRSF4/IL21R/FAS/IL9R/IL4/ACVR1/IL15RA/TNFRSF25/PF4/GDF11/CCR2/TNFRSF10D	13
KEGG	hsa05212	Pancreatic cancer	5/215	76/8135	0.05017	0.8706	0.8706	RPS6KB1/PIK3R3/PLD1/GADD45B/EGF	5
KEGG	hsa05320	Autoimmune thyroid disease	4/215	53/8135	0.0508	0.8706	0.8706	CD40/FAS/HLA-DOA/IL4	4
KEGG	hsa04932	Non-alcoholic fatty liver disease	8/215	155/8135	0.05286	0.8706	0.8706	FAS/CYCS/MLX/ADIPOQ/PIK3R3/ADIPOR1/CYP2E1/COX4I2	8
KEGG	hsa03410	Base excision repair	3/215	33/8135	0.05556	0.8706	0.8706	MUTYH/LIG1/POLD2	3
KEGG	hsa00603	Glycosphingolipid biosynthesis - globo and isoglobo series	2/215	15/8135	0.05824	0.8706	0.8706	FUT2/GLA	2
KEGG	hsa05134	Legionellosis	4/215	57/8135	0.06325	0.8982	0.8982	CYCS/CD14/BNIP3/C3	4
KEGG	hsa03030	DNA replication	3/215	36/8135	0.0687	0.9003	0.9003	LIG1/POLA2/POLD2	3
KEGG	hsa00450	Selenocompound metabolism	2/215	17/8135	0.0729	0.9003	0.9003	TXNRD2/SEPHS1	2
KEGG	hsa05145	Toxoplasmosis	6/215	112/8135	0.07587	0.9003	0.9003	LAMC1/CD40/HLA-DOA/CYCS/IRAK1/CIITA	6
KEGG	hsa04742	Taste transduction	5/215	86/8135	0.0769	0.9003	0.9003	TAS2R13/ADCY8/PLCB2/TAS2R19/TAS2R50	5
KEGG	hsa04213	Longevity regulating pathway - multiple species	4/215	62/8135	0.08086	0.9003	0.9003	FOXO3/RPS6KB1/ADCY8/PIK3R3	4
KEGG	hsa04512	ECM-receptor interaction	5/215	88/8135	0.08302	0.9003	0.9003	LAMC1/SV2C/ITGA10/COL6A6/ITGA2	5
KEGG	hsa05169	Epstein-Barr virus infection	9/215	202/8135	0.08702	0.9003	0.9003	CD40/FAS/HLA-DOA/CYCS/TNFAIP3/PIK3R3/IRAK1/IKBKE/GADD45B	9
KEGG	hsa05222	Small cell lung cancer	5/215	92/8135	0.096	0.9003	0.9003	LAMC1/CYCS/PIK3R3/ITGA2/GADD45B	5
KEGG	hsa00100	Steroid biosynthesis	2/215	20/8135	0.09679	0.9003	0.9003	FDFT1/NSDHL	2
KEGG	hsa05332	Graft-versus-host disease	3/215	42/8135	0.09868	0.9003	0.9003	KLRD1/FAS/HLA-DOA	3
KEGG	hsa05414	Dilated cardiomyopathy	5/215	96/8135	0.1099	0.9003	0.9003	ITGA10/ADCY8/ITGA2/ACTC1/TNNC1	5
KEGG	hsa04070	Phosphatidylinositol signaling system	5/215	97/8135	0.1136	0.9003	0.9003	INPP5E/PLCD4/PLCZ1/PIK3R3/PLCB2	5
KEGG	hsa05417	Lipid and atherosclerosis	9/215	215/8135	0.116	0.9003	0.9003	CD40/FAS/CYCS/PIK3R3/PLCB2/CD14/IRAK1/IKBKE/VLDLR	9
KEGG	hsa05231	Choline metabolism in cancer	5/215	98/8135	0.1173	0.9003	0.9003	RPS6KB1/PIK3R3/PLD1/GPCPD1/EGF	5
KEGG	hsa04640	Hematopoietic cell lineage	5/215	99/8135	0.121	0.9003	0.9003	IL9R/HLA-DOA/IL4/ITGA2/CD14	5
KEGG	hsa05223	Non-small cell lung cancer	4/215	72/8135	0.1224	0.9003	0.9003	FOXO3/PIK3R3/GADD45B/EGF	4
KEGG	hsa03430	Mismatch repair	2/215	23/8135	0.1225	0.9003	0.9003	LIG1/POLD2	2
KEGG	hsa04926	Relaxin signaling pathway	6/215	129/8135	0.1263	0.9003	0.9003	RLN1/ADCY8/VEGFB/PIK3R3/PLCB2/RXFP1	6
KEGG	hsa00562	Inositol phosphate metabolism	4/215	73/8135	0.127	0.9003	0.9003	INPP5E/PLCD4/PLCZ1/PLCB2	4
KEGG	hsa01524	Platinum drug resistance	4/215	73/8135	0.127	0.9003	0.9003	POLH/FAS/CYCS/PIK3R3	4
KEGG	hsa05142	Chagas disease	5/215	102/8135	0.1326	0.9003	0.9003	FAS/PIK3R3/PLCB2/IRAK1/C3	5
KEGG	hsa05202	Transcriptional misregulation in cancer	8/215	193/8135	0.1388	0.9003	0.9003	CD40/IGFBP3/SUPT3H/CD14/KDM6A/GADD45B/LMO2/PAX7	8
KEGG	hsa04064	NF-kappa B signaling pathway	5/215	104/8135	0.1406	0.9003	0.9003	CD40/TNFAIP3/CD14/IRAK1/GADD45B	5
KEGG	hsa04620	Toll-like receptor signaling pathway	5/215	104/8135	0.1406	0.9003	0.9003	CD40/PIK3R3/CD14/IRAK1/IKBKE	5
KEGG	hsa05140	Leishmaniasis	4/215	77/8135	0.146	0.9003	0.9003	HLA-DOA/IL4/IRAK1/C3	4
KEGG	hsa04612	Antigen processing and presentation	4/215	78/8135	0.1509	0.9003	0.9003	KLRD1/HLA-DOA/CIITA/NFYC	4
KEGG	hsa01521	EGFR tyrosine kinase inhibitor resistance	4/215	79/8135	0.1559	0.9003	0.9003	FOXO3/RPS6KB1/PIK3R3/EGF	4
KEGG	hsa05162	Measles	6/215	139/8135	0.162	0.9003	0.9003	FAS/CYCS/TNFAIP3/PIK3R3/IRAK1/IKBKE	6
KEGG	hsa04510	Focal adhesion	8/215	201/8135	0.1628	0.9003	0.9003	LAMC1/MYLK4/ITGA10/VEGFB/COL6A6/PIK3R3/ITGA2/EGF	8
KEGG	hsa05165	Human papillomavirus infection	12/215	331/8135	0.1661	0.9003	0.9003	LAMC1/FAS/AXIN2/PPP2R3C/RPS6KB1/ITGA10/COL6A6/PIK3R3/ITGA2/IKBKE/ATP6V0E1/EGF	12
KEGG	hsa05164	Influenza A	7/215	171/8135	0.1668	0.9003	0.9003	FAS/HLA-DOA/CYCS/PIK3R3/IKBKE/TMPRSS11D/CIITA	7
KEGG	hsa03460	Fanconi anemia pathway	3/215	54/8135	0.1707	0.9003	0.9003	POLH/TELO2/FANCA	3
KEGG	hsa04392	Hippo signaling pathway - multiple species	2/215	29/8135	0.1779	0.9003	0.9003	DCHS1/RASSF4	2
KEGG	hsa04020	Calcium signaling pathway	9/215	240/8135	0.1846	0.9003	0.9003	PLCD4/PHKA2/PLCZ1/MYLK4/ADCY8/VEGFB/PLCB2/TNNC1/EGF	9
KEGG	hsa00030	Pentose phosphate pathway	2/215	30/8135	0.1875	0.9003	0.9003	PRPS1L1/PRPS2	2
KEGG	hsa04710	Circadian rhythm	2/215	31/8135	0.1971	0.9003	0.9003	FBXL3/CRY2	2
KEGG	hsa04072	Phospholipase D signaling pathway	6/215	148/8135	0.1974	0.9003	0.9003	ADCY8/PIK3R3/PLCB2/PLD1/AGPAT4/EGF	6
KEGG	hsa05152	Tuberculosis	7/215	180/8135	0.1989	0.9003	0.9003	HLA-DOA/CYCS/CD14/IRAK1/CIITA/C3/NFYC	7
KEGG	hsa04261	Adrenergic signaling in cardiomyocytes	6/215	150/8135	0.2056	0.9003	0.9003	PPP2R3C/ADCY8/PLCB2/ACTC1/CREM/TNNC1	6
KEGG	hsa04071	Sphingolipid signaling pathway	5/215	119/8135	0.2065	0.9003	0.9003	PPP2R3C/SGPP2/PIK3R3/PLCB2/PLD1	5
KEGG	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	4/215	89/8135	0.2088	0.9003	0.9003	RPS6KB1/PIK3R3/CD274/EGF	4
KEGG	hsa05416	Viral myocarditis	3/215	60/8135	0.2111	0.9003	0.9003	CD40/HLA-DOA/CYCS	3
KEGG	hsa04621	NOD-like receptor signaling pathway	7/215	184/8135	0.214	0.9003	0.9003	TNFAIP3/DNM1L/PLCB2/TRPV2/AIM2/CASP5/IKBKE	7
KEGG	hsa05410	Hypertrophic cardiomyopathy	4/215	90/8135	0.2143	0.9003	0.9003	ITGA10/ITGA2/ACTC1/TNNC1	4
KEGG	hsa04130	SNARE interactions in vesicular transport	2/215	33/8135	0.2166	0.9003	0.9003	VTI1A/VAMP1	2
KEGG	hsa00561	Glycerolipid metabolism	3/215	61/8135	0.218	0.9003	0.9003	PNPLA3/GLA/AGPAT4	3
KEGG	hsa04611	Platelet activation	5/215	124/8135	0.2304	0.9003	0.9003	MYLK4/ADCY8/PIK3R3/PLCB2/ITGA2	5
KEGG	hsa04623	Cytosolic DNA-sensing pathway	3/215	63/8135	0.232	0.9003	0.9003	AIM2/IKBKE/POLR3G	3
KEGG	hsa05160	Hepatitis C	6/215	157/8135	0.2354	0.9003	0.9003	FAS/CYCS/CLDN5/PIK3R3/IKBKE/EGF	6
KEGG	hsa04927	Cortisol synthesis and secretion	3/215	65/8135	0.2461	0.9003	0.9003	ADCY8/PLCB2/KCNK3	3
KEGG	hsa05321	Inflammatory bowel disease	3/215	65/8135	0.2461	0.9003	0.9003	IL21R/HLA-DOA/IL4	3
KEGG	hsa00970	Aminoacyl-tRNA biosynthesis	3/215	66/8135	0.2533	0.9003	0.9003	LARS2/SARS2/PARS2	3
KEGG	hsa05143	African trypanosomiasis	2/215	37/8135	0.2559	0.9003	0.9003	FAS/PLCB2	2
KEGG	hsa04630	JAK-STAT signaling pathway	6/215	162/8135	0.2574	0.9003	0.9003	IL21R/IL9R/IL4/IL15RA/PIK3R3/EGF	6
KEGG	hsa00564	Glycerophospholipid metabolism	4/215	98/8135	0.26	0.9003	0.9003	PLD1/AGPAT4/GPCPD1/LPCAT1	4
KEGG	hsa04750	Inflammatory mediator regulation of TRP channels	4/215	98/8135	0.26	0.9003	0.9003	ADCY8/PIK3R3/PLCB2/TRPV2	4
KEGG	hsa05221	Acute myeloid leukemia	3/215	67/8135	0.2604	0.9003	0.9003	RPS6KB1/PIK3R3/CD14	3
KEGG	hsa04068	FoxO signaling pathway	5/215	131/8135	0.2652	0.9003	0.9003	FOXO3/PIK3R3/BNIP3/GADD45B/EGF	5
KEGG	hsa05340	Primary immunodeficiency	2/215	38/8135	0.2658	0.9003	0.9003	CD40/CIITA	2
KEGG	hsa04933	AGE-RAGE signaling pathway in diabetic complications	4/215	100/8135	0.2718	0.9003	0.9003	PLCD4/VEGFB/PIK3R3/PLCB2	4
KEGG	hsa04920	Adipocytokine signaling pathway	3/215	69/8135	0.2748	0.9003	0.9003	ACSL4/ADIPOQ/ADIPOR1	3
KEGG	hsa05146	Amoebiasis	4/215	102/8135	0.2836	0.9003	0.9003	LAMC1/PIK3R3/PLCB2/CD14	4
KEGG	hsa03450	Non-homologous end-joining	1/215	13/8135	0.2942	0.9003	0.9003	LIG4	1
KEGG	hsa04216	Ferroptosis	2/215	41/8135	0.2954	0.9003	0.9003	ACSL4/GSS	2
KEGG	hsa05218	Melanoma	3/215	72/8135	0.2965	0.9003	0.9003	PIK3R3/GADD45B/EGF	3
KEGG	hsa04371	Apelin signaling pathway	5/215	139/8135	0.3062	0.9003	0.9003	MYLK4/RPS6KB1/ADCY8/PLCB2/PIK3R4	5
KEGG	hsa00071	Fatty acid degradation	2/215	43/8135	0.3151	0.9003	0.9003	ACSL4/ECI1	2
KEGG	hsa00860	Porphyrin metabolism	2/215	43/8135	0.3151	0.9003	0.9003	MMAB/ALAS2	2
KEGG	hsa04940	Type I diabetes mellitus	2/215	43/8135	0.3151	0.9003	0.9003	FAS/HLA-DOA	2
KEGG	hsa04140	Autophagy - animal	5/215	141/8135	0.3167	0.9003	0.9003	RAB39B/RPS6KB1/PIK3R3/BNIP3/PIK3R4	5
KEGG	hsa01230	Biosynthesis of amino acids	3/215	75/8135	0.3184	0.9003	0.9003	PRPS1L1/ACO2/PRPS2	3
KEGG	hsa03320	PPAR signaling pathway	3/215	75/8135	0.3184	0.9003	0.9003	ACSL4/ADIPOQ/SORBS1	3
KEGG	hsa04918	Thyroid hormone synthesis	3/215	75/8135	0.3184	0.9003	0.9003	GPX7/ADCY8/PLCB2	3
KEGG	hsa05214	Glioma	3/215	75/8135	0.3184	0.9003	0.9003	PIK3R3/GADD45B/EGF	3
KEGG	hsa04971	Gastric acid secretion	3/215	76/8135	0.3256	0.9003	0.9003	MYLK4/ADCY8/PLCB2	3
KEGG	hsa05133	Pertussis	3/215	76/8135	0.3256	0.9003	0.9003	CD14/IRAK1/C3	3
KEGG	hsa05017	Spinocerebellar ataxia	5/215	143/8135	0.3271	0.9003	0.9003	CYCS/PIK3R3/PLCB2/VLDLR/PIK3R4	5
KEGG	hsa00730	Thiamine metabolism	1/215	15/8135	0.3311	0.9003	0.9003	TPK1	1
KEGG	hsa04151	PI3K-Akt signaling pathway	11/215	354/8135	0.334	0.9003	0.9003	LAMC1/PPP2R3C/FOXO3/RPS6KB1/IL4/ITGA10/VEGFB/COL6A6/PIK3R3/ITGA2/EGF	11
KEGG	hsa04668	TNF signaling pathway	4/215	112/8135	0.3436	0.9003	0.9003	FAS/TNFAIP3/DNM1L/PIK3R3	4
KEGG	hsa04930	Type II diabetes mellitus	2/215	46/8135	0.3443	0.9003	0.9003	ADIPOQ/PIK3R3	2
KEGG	hsa05224	Breast cancer	5/215	147/8135	0.3481	0.9003	0.9003	AXIN2/RPS6KB1/PIK3R3/GADD45B/EGF	5
KEGG	hsa03420	Nucleotide excision repair	2/215	47/8135	0.3539	0.9003	0.9003	LIG1/POLD2	2
KEGG	hsa04973	Carbohydrate digestion and absorption	2/215	47/8135	0.3539	0.9003	0.9003	PIK3R3/PLCB2	2
KEGG	hsa05226	Gastric cancer	5/215	149/8135	0.3587	0.9003	0.9003	AXIN2/RPS6KB1/PIK3R3/GADD45B/EGF	5
KEGG	hsa01200	Carbon metabolism	4/215	115/8135	0.3617	0.9003	0.9003	PRPS1L1/ACO2/HIBCH/PRPS2	4
KEGG	hsa00280	Valine, leucine and isoleucine degradation	2/215	48/8135	0.3635	0.9003	0.9003	HIBCH/MCCC2	2
KEGG	hsa04146	Peroxisome	3/215	82/8135	0.3693	0.9003	0.9003	ACSL4/PEX7/PEX12	3
KEGG	hsa00565	Ether lipid metabolism	2/215	49/8135	0.3731	0.9003	0.9003	PLD1/LPCAT1	2
KEGG	hsa04010	MAPK signaling pathway	9/215	294/8135	0.3743	0.9003	0.9003	MAP4K3/FAS/MAPKAPK5/VEGFB/CD14/IRAK1/DUSP2/GADD45B/EGF	9
KEGG	hsa04145	Phagosome	5/215	152/8135	0.3745	0.9003	0.9003	HLA-DOA/ITGA2/CD14/C3/ATP6V0E1	5
KEGG	hsa01240	Biosynthesis of cofactors	5/215	153/8135	0.3798	0.9003	0.9003	MMAB/NMNAT1/GSS/ALAS2/TPK1	5
KEGG	hsa00061	Fatty acid biosynthesis	1/215	18/8135	0.3828	0.9003	0.9003	ACSL4	1
KEGG	hsa04935	Growth hormone synthesis, secretion and action	4/215	119/8135	0.3858	0.9003	0.9003	IGFBP3/ADCY8/PIK3R3/PLCB2	4
KEGG	hsa04934	Cushing syndrome	5/215	155/8135	0.3904	0.9003	0.9003	AXIN2/ADCY8/PLCB2/KCNK3/AIPL1	5
KEGG	hsa04012	ErbB signaling pathway	3/215	85/8135	0.3909	0.9003	0.9003	RPS6KB1/PIK3R3/EGF	3
KEGG	hsa04913	Ovarian steroidogenesis	2/215	51/8135	0.392	0.9003	0.9003	ADCY8/HSD17B1	2
KEGG	hsa04062	Chemokine signaling pathway	6/215	192/8135	0.3973	0.9003	0.9003	FOXO3/ADCY8/PIK3R3/PLCB2/PF4/CCR2	6
KEGG	hsa04919	Thyroid hormone signaling pathway	4/215	121/8135	0.3979	0.9003	0.9003	PLCD4/PLCZ1/PIK3R3/PLCB2	4
KEGG	hsa04911	Insulin secretion	3/215	86/8135	0.3981	0.9003	0.9003	RIMS2/ADCY8/PLCB2	3
KEGG	hsa01210	2-Oxocarboxylic acid metabolism	1/215	19/8135	0.3992	0.9003	0.9003	ACO2	1
KEGG	hsa00600	Sphingolipid metabolism	2/215	52/8135	0.4014	0.9003	0.9003	SGPP2/GLA	2
KEGG	hsa04260	Cardiac muscle contraction	3/215	87/8135	0.4052	0.9003	0.9003	ACTC1/COX4I2/TNNC1	3
KEGG	hsa05167	Kaposi sarcoma-associated herpesvirus infection	6/215	194/8135	0.4069	0.9003	0.9003	FAS/CYCS/CD200R1/PIK3R3/IKBKE/C3	6
KEGG	hsa04540	Gap junction	3/215	88/8135	0.4124	0.9003	0.9003	ADCY8/PLCB2/EGF	3
KEGG	hsa00670	One carbon pool by folate	1/215	20/8135	0.4151	0.9003	0.9003	TYMS	1
KEGG	hsa04727	GABAergic synapse	3/215	89/8135	0.4195	0.9003	0.9003	ADCY8/GABRR3/SLC12A5	3
KEGG	hsa05161	Hepatitis B	5/215	162/8135	0.4272	0.9003	0.9003	FAS/CYCS/PIK3R3/IRAK1/IKBKE	5
KEGG	hsa04340	Hedgehog signaling pathway	2/215	56/8135	0.4382	0.9003	0.9003	SMURF1/HHATL	2
KEGG	hsa04923	Regulation of lipolysis in adipocytes	2/215	56/8135	0.4382	0.9003	0.9003	ADCY8/PIK3R3	2
KEGG	hsa00230	Purine metabolism	4/215	128/8135	0.4396	0.9003	0.9003	PRPS1L1/ADCY8/GDA/PRPS2	4
KEGG	hsa04912	GnRH signaling pathway	3/215	93/8135	0.4476	0.9003	0.9003	ADCY8/PLCB2/PLD1	3
KEGG	hsa04350	TGF-beta signaling pathway	3/215	94/8135	0.4545	0.9003	0.9003	RPS6KB1/ACVR1/SMURF1	3
KEGG	hsa04657	IL-17 signaling pathway	3/215	94/8135	0.4545	0.9003	0.9003	TNFAIP3/IL4/IKBKE	3
KEGG	hsa00480	Glutathione metabolism	2/215	58/8135	0.4561	0.9003	0.9003	GPX7/GSS	2
KEGG	hsa04650	Natural killer cell mediated cytotoxicity	4/215	131/8135	0.4573	0.9003	0.9003	KLRD1/FAS/PIK3R3/RAET1E	4
KEGG	hsa05225	Hepatocellular carcinoma	5/215	168/8135	0.4584	0.9003	0.9003	TXNRD2/AXIN2/RPS6KB1/PIK3R3/GADD45B	5
KEGG	hsa04614	Renin-angiotensin system	1/215	23/8135	0.4604	0.9003	0.9003	PREP	1
KEGG	hsa05150	Staphylococcus aureus infection	3/215	96/8135	0.4683	0.9003	0.9003	HLA-DOA/DSG1/C3	3
KEGG	hsa04977	Vitamin digestion and absorption	1/215	24/8135	0.4747	0.9003	0.9003	TCN2	1
KEGG	hsa04270	Vascular smooth muscle contraction	4/215	134/8135	0.4748	0.9003	0.9003	CALD1/MYLK4/ADCY8/PLCB2	4
KEGG	hsa04666	Fc gamma R-mediated phagocytosis	3/215	97/8135	0.4751	0.9003	0.9003	RPS6KB1/PIK3R3/PLD1	3
KEGG	hsa01522	Endocrine resistance	3/215	98/8135	0.4819	0.9003	0.9003	RPS6KB1/ADCY8/PIK3R3	3
KEGG	hsa04925	Aldosterone synthesis and secretion	3/215	98/8135	0.4819	0.9003	0.9003	ADCY8/PLCB2/KCNK3	3
KEGG	hsa00140	Steroid hormone biosynthesis	2/215	61/8135	0.4823	0.9003	0.9003	HSD17B1/CYP2E1	2
KEGG	hsa00590	Arachidonic acid metabolism	2/215	61/8135	0.4823	0.9003	0.9003	GPX7/CYP2E1	2
KEGG	hsa04210	Apoptosis	4/215	136/8135	0.4863	0.9003	0.9003	FAS/CYCS/PIK3R3/GADD45B	4
KEGG	hsa05207	Chemical carcinogenesis - receptor activation	6/215	212/8135	0.4913	0.9003	0.9003	RPS6KB1/ADCY8/PIK3R3/IKBKE/AIPL1/EGF	6
KEGG	hsa04910	Insulin signaling pathway	4/215	137/8135	0.492	0.9003	0.9003	PHKA2/RPS6KB1/PIK3R3/SORBS1	4
KEGG	hsa04061	Viral protein interaction with cytokine and cytokine receptor	3/215	100/8135	0.4954	0.9003	0.9003	PF4/CCR2/TNFRSF10D	3
KEGG	hsa04915	Estrogen signaling pathway	4/215	138/8135	0.4977	0.9003	0.9003	ADCY8/PIK3R3/PLCB2/EBAG9	4
KEGG	hsa05217	Basal cell carcinoma	2/215	63/8135	0.4994	0.9003	0.9003	AXIN2/GADD45B	2
KEGG	hsa00563	Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	1/215	26/8135	0.5022	0.9003	0.9003	PIGN	1
KEGG	hsa00790	Folate biosynthesis	1/215	26/8135	0.5022	0.9003	0.9003	QDPR	1
KEGG	hsa04929	GnRH secretion	2/215	64/8135	0.5078	0.9003	0.9003	PIK3R3/PLCB2	2
KEGG	hsa04972	Pancreatic secretion	3/215	102/8135	0.5087	0.9003	0.9003	ADCY8/PLCB2/RAB27B	3
KEGG	hsa04966	Collecting duct acid secretion	1/215	27/8135	0.5154	0.9003	0.9003	ATP6V0E1	1
KEGG	hsa04810	Regulation of actin cytoskeleton	6/215	218/8135	0.5187	0.9003	0.9003	MYLK4/ITGA10/PIK3R3/ITGA2/DIAPH2/EGF	6
KEGG	hsa04360	Axon guidance	5/215	182/8135	0.5292	0.9003	0.9003	SEMA3D/SEMA3F/PIK3R3/PLXNB2/EPHB6	5
KEGG	hsa04720	Long-term potentiation	2/215	67/8135	0.5325	0.9003	0.9003	ADCY8/PLCB2	2
KEGG	hsa04928	Parathyroid hormone synthesis, secretion and action	3/215	106/8135	0.5347	0.9003	0.9003	ADCY8/PLCB2/PLD1	3
KEGG	hsa04664	Fc epsilon RI signaling pathway	2/215	68/8135	0.5405	0.9003	0.9003	IL4/PIK3R3	2
KEGG	hsa00591	Linoleic acid metabolism	1/215	29/8135	0.5407	0.9003	0.9003	CYP2E1	1
KEGG	hsa05208	Chemical carcinogenesis - reactive oxygen species	6/215	223/8135	0.541	0.9003	0.9003	FOXO3/PIK3R3/PLD1/CYP2E1/COX4I2/EGF	6
KEGG	hsa04659	Th17 cell differentiation	3/215	108/8135	0.5474	0.9003	0.9003	IL21R/HLA-DOA/IL4	3
KEGG	hsa04931	Insulin resistance	3/215	108/8135	0.5474	0.9003	0.9003	MLX/RPS6KB1/PIK3R3	3
KEGG	hsa05163	Human cytomegalovirus infection	6/215	225/8135	0.5499	0.9003	0.9003	FAS/CYCS/RPS6KB1/ADCY8/PIK3R3/PLCB2	6
KEGG	hsa00020	Citrate cycle (TCA cycle)	1/215	30/8135	0.5529	0.9003	0.9003	ACO2	1
KEGG	hsa00630	Glyoxylate and dicarboxylate metabolism	1/215	30/8135	0.5529	0.9003	0.9003	ACO2	1
KEGG	hsa01523	Antifolate resistance	1/215	30/8135	0.5529	0.9003	0.9003	TYMS	1
KEGG	hsa04723	Retrograde endocannabinoid signaling	4/215	148/8135	0.5531	0.9003	0.9003	ADCY8/NAPEPLD/PLCB2/GABRR3	4
KEGG	hsa04066	HIF-1 signaling pathway	3/215	109/8135	0.5537	0.9003	0.9003	RPS6KB1/PIK3R3/EGF	3
KEGG	hsa04917	Prolactin signaling pathway	2/215	70/8135	0.5562	0.9003	0.9003	FOXO3/PIK3R3	2
KEGG	hsa04514	Cell adhesion molecules	4/215	149/8135	0.5585	0.9003	0.9003	CD40/HLA-DOA/CLDN5/CD274	4
KEGG	hsa04520	Adherens junction	2/215	71/8135	0.564	0.9003	0.9003	PTPRB/SORBS1	2
KEGG	hsa00052	Galactose metabolism	1/215	31/8135	0.5648	0.9003	0.9003	GLA	1
KEGG	hsa00410	beta-Alanine metabolism	1/215	31/8135	0.5648	0.9003	0.9003	HIBCH	1
KEGG	hsa04137	Mitophagy - animal	2/215	72/8135	0.5716	0.9003	0.9003	FOXO3/BNIP3	2
KEGG	hsa00640	Propanoate metabolism	1/215	32/8135	0.5763	0.9003	0.9003	HIBCH	1
KEGG	hsa04136	Autophagy - other	1/215	32/8135	0.5763	0.9003	0.9003	PIK3R4	1
KEGG	hsa04215	Apoptosis - multiple species	1/215	32/8135	0.5763	0.9003	0.9003	CYCS	1
KEGG	hsa04725	Cholinergic synapse	3/215	113/8135	0.5783	0.9003	0.9003	ADCY8/PIK3R3/PLCB2	3
KEGG	hsa04714	Thermogenesis	6/215	232/8135	0.5801	0.9003	0.9003	ACSL4/RPS6KB1/ADCY8/COX20/COA4/COX4I2	6
KEGG	hsa04724	Glutamatergic synapse	3/215	114/8135	0.5843	0.9019	0.9019	ADCY8/PLCB2/PLD1	3
KEGG	hsa00051	Fructose and mannose metabolism	1/215	33/8135	0.5876	0.902	0.902	ENOSF1	1
KEGG	hsa04150	mTOR signaling pathway	4/215	156/8135	0.5951	0.9034	0.9034	STRADB/RPS6KB1/PIK3R3/TELO2	4
KEGG	hsa04218	Cellular senescence	4/215	156/8135	0.5951	0.9034	0.9034	FOXO3/IGFBP3/PIK3R3/GADD45B	4
KEGG	hsa03020	RNA polymerase	1/215	34/8135	0.5985	0.9034	0.9034	POLR3G	1
KEGG	hsa05220	Chronic myeloid leukemia	2/215	76/8135	0.6012	0.9034	0.9034	PIK3R3/GADD45B	2
KEGG	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	2/215	77/8135	0.6084	0.9069	0.9069	ITGA10/ITGA2	2
KEGG	hsa04217	Necroptosis	4/215	159/8135	0.6102	0.9069	0.9069	FAS/TNFAIP3/DNM1L/SPATA2	4
KEGG	hsa04722	Neurotrophin signaling pathway	3/215	119/8135	0.6136	0.9069	0.9069	FOXO3/PIK3R3/IRAK1	3
KEGG	hsa00350	Tyrosine metabolism	1/215	36/8135	0.6195	0.9069	0.9069	HGD	1
KEGG	hsa00760	Nicotinate and nicotinamide metabolism	1/215	36/8135	0.6195	0.9069	0.9069	NMNAT1	1
KEGG	hsa04960	Aldosterone-regulated sodium reabsorption	1/215	37/8135	0.6296	0.9123	0.9123	PIK3R3	1
KEGG	hsa05216	Thyroid cancer	1/215	37/8135	0.6296	0.9123	0.9123	GADD45B	1
KEGG	hsa00513	Various types of N-glycan biosynthesis	1/215	39/8135	0.649	0.9157	0.9157	MGAT4A	1
KEGG	hsa05132	Salmonella infection	6/215	249/8135	0.6491	0.9157	0.9157	DCTN5/CYCS/CD14/IRAK1/CASP5/VPS33A	6
KEGG	hsa04015	Rap1 signaling pathway	5/215	210/8135	0.6565	0.9157	0.9157	ADCY8/VEGFB/PIK3R3/PLCB2/EGF	5
KEGG	hsa04530	Tight junction	4/215	169/8135	0.658	0.9157	0.9157	CLDN5/TJP3/MPDZ/YBX3	4
KEGG	hsa00260	Glycine, serine and threonine metabolism	1/215	40/8135	0.6584	0.9157	0.9157	ALAS2	1
KEGG	hsa05033	Nicotine addiction	1/215	40/8135	0.6584	0.9157	0.9157	GABRR3	1
KEGG	hsa01232	Nucleotide metabolism	2/215	85/8135	0.6621	0.9157	0.9157	TYMS/GDA	2
KEGG	hsa04610	Complement and coagulation cascades	2/215	85/8135	0.6621	0.9157	0.9157	CFHR5/C3	2
KEGG	hsa05170	Human immunodeficiency virus 1 infection	5/215	212/8135	0.6647	0.9157	0.9157	FAS/CYCS/RPS6KB1/PIK3R3/IRAK1	5
KEGG	hsa03440	Homologous recombination	1/215	41/8135	0.6674	0.9157	0.9157	POLD2	1
KEGG	hsa05219	Bladder cancer	1/215	41/8135	0.6674	0.9157	0.9157	EGF	1
KEGG	hsa04114	Oocyte meiosis	3/215	131/8135	0.678	0.9171	0.9171	PLCZ1/FBXO5/ADCY8	3
KEGG	hsa04728	Dopaminergic synapse	3/215	132/8135	0.683	0.9171	0.9171	PPP2R3C/PLCB2/DRD4	3
KEGG	hsa04976	Bile secretion	2/215	89/8135	0.6867	0.9171	0.9171	ADCY8/SLC51A	2
KEGG	hsa05010	Alzheimer disease	9/215	384/8135	0.6925	0.9171	0.9171	FAS/IDE/AXIN2/CYCS/PIK3R3/PLCB2/SNCA/COX4I2/PIK3R4	9
KEGG	hsa00190	Oxidative phosphorylation	3/215	134/8135	0.6928	0.9171	0.9171	CYCS/COX4I2/ATP6V0E1	3
KEGG	hsa04962	Vasopressin-regulated water reabsorption	1/215	44/8135	0.6932	0.9171	0.9171	DCTN5	1
KEGG	hsa05032	Morphine addiction	2/215	91/8135	0.6984	0.9171	0.9171	ADCY8/GABRR3	2
KEGG	hsa05322	Systemic lupus erythematosus	3/215	136/8135	0.7024	0.9171	0.9171	CD40/HLA-DOA/C3	3
KEGG	hsa05166	Human T-cell leukemia virus 1 infection	5/215	222/8135	0.7039	0.9171	0.9171	CD40/HLA-DOA/ADCY8/IL15RA/PIK3R3	5
KEGG	hsa04658	Th1 and Th2 cell differentiation	2/215	92/8135	0.7042	0.9171	0.9171	HLA-DOA/IL4	2
KEGG	hsa04970	Salivary secretion	2/215	93/8135	0.7098	0.9171	0.9171	ADCY8/PLCB2	2
KEGG	hsa05323	Rheumatoid arthritis	2/215	93/8135	0.7098	0.9171	0.9171	HLA-DOA/ATP6V0E1	2
KEGG	hsa05022	Pathways of neurodegeneration - multiple diseases	11/215	476/8135	0.7211	0.9171	0.9171	FAS/DCTN5/AXIN2/CYCS/RAB39B/GPX7/PLCB2/SNCA/SIGMAR1/COX4I2/PIK3R4	11
KEGG	hsa04080	Neuroactive ligand-receptor interaction	8/215	353/8135	0.7222	0.9171	0.9171	RLN1/MC5R/RXFP1/DRD4/GABRR3/OPRK1/MCHR2/C3	8
KEGG	hsa03015	mRNA surveillance pathway	2/215	97/8135	0.7315	0.9171	0.9171	PPP2R3C/CSTF2T	2
KEGG	hsa04713	Circadian entrainment	2/215	97/8135	0.7315	0.9171	0.9171	ADCY8/PLCB2	2
KEGG	hsa05215	Prostate cancer	2/215	97/8135	0.7315	0.9171	0.9171	PIK3R3/EGF	2
KEGG	hsa04550	Signaling pathways regulating pluripotency of stem cells	3/215	143/8135	0.7342	0.9171	0.9171	AXIN2/ACVR1/PIK3R3	3
KEGG	hsa00510	N-Glycan biosynthesis	1/215	50/8135	0.739	0.9171	0.9171	MGAT4A	1
KEGG	hsa05110	Vibrio cholerae infection	1/215	50/8135	0.739	0.9171	0.9171	ATP6V0E1	1
KEGG	hsa05144	Malaria	1/215	50/8135	0.739	0.9171	0.9171	CD40	1
KEGG	hsa05171	Coronavirus disease - COVID-19	5/215	232/8135	0.7397	0.9171	0.9171	PIK3R3/IRAK1/IKBKE/C3/RPS4Y1	5
KEGG	hsa00270	Cysteine and methionine metabolism	1/215	51/8135	0.746	0.9171	0.9171	GSS	1
KEGG	hsa00330	Arginine and proline metabolism	1/215	51/8135	0.746	0.9171	0.9171	P4HA1	1
KEGG	hsa04916	Melanogenesis	2/215	101/8135	0.7518	0.9203	0.9203	ADCY8/PLCB2	2
KEGG	hsa04914	Progesterone-mediated oocyte maturation	2/215	102/8135	0.7566	0.9215	0.9215	ADCY8/PIK3R3	2
KEGG	hsa04961	Endocrine and other factor-regulated calcium reabsorption	1/215	53/8135	0.7593	0.9215	0.9215	PLCB2	1
KEGG	hsa04625	C-type lectin receptor signaling pathway	2/215	104/8135	0.7661	0.9219	0.9219	PIK3R3/IKBKE	2
KEGG	hsa04660	T cell receptor signaling pathway	2/215	104/8135	0.7661	0.9219	0.9219	IL4/PIK3R3	2
KEGG	hsa05130	Pathogenic Escherichia coli infection	4/215	197/8135	0.77	0.9227	0.9227	FAS/CYCS/CLDN5/IRAK1	4
KEGG	hsa04921	Oxytocin signaling pathway	3/215	154/8135	0.7787	0.9265	0.9265	MYLK4/ADCY8/PLCB2	3
KEGG	hsa04922	Glucagon signaling pathway	2/215	107/8135	0.7797	0.9265	0.9265	PHKA2/PLCB2	2
KEGG	hsa01212	Fatty acid metabolism	1/215	57/8135	0.7839	0.9267	0.9267	ACSL4	1
KEGG	hsa03008	Ribosome biogenesis in eukaryotes	2/215	109/8135	0.7884	0.9267	0.9267	RBM28/NOP58	2
KEGG	hsa00240	Pyrimidine metabolism	1/215	58/8135	0.7897	0.9267	0.9267	TYMS	1
KEGG	hsa04370	VEGF signaling pathway	1/215	59/8135	0.7953	0.9268	0.9268	PIK3R3	1
KEGG	hsa05205	Proteoglycans in cancer	4/215	205/8135	0.7962	0.9268	0.9268	FAS/RPS6KB1/PIK3R3/ITGA2	4
KEGG	hsa04730	Long-term depression	1/215	60/8135	0.8007	0.9282	0.9282	PLCB2	1
KEGG	hsa04670	Leukocyte transendothelial migration	2/215	114/8135	0.8088	0.9338	0.9338	CLDN5/PIK3R3	2
KEGG	hsa04022	cGMP-PKG signaling pathway	3/215	167/8135	0.8232	0.9415	0.9415	MYLK4/ADCY8/PLCB2	3
KEGG	hsa04310	Wnt signaling pathway	3/215	167/8135	0.8232	0.9415	0.9415	LGR4/AXIN2/PLCB2	3
KEGG	hsa05016	Huntington disease	6/215	306/8135	0.8255	0.9415	0.9415	DCTN5/CYCS/GPX7/PLCB2/COX4I2/PIK3R4	6
KEGG	hsa04924	Renin secretion	1/215	69/8135	0.8437	0.9443	0.9443	PLCB2	1
KEGG	hsa05204	Chemical carcinogenesis - DNA adducts	1/215	69/8135	0.8437	0.9443	0.9443	CYP2E1	1
KEGG	hsa05211	Renal cell carcinoma	1/215	69/8135	0.8437	0.9443	0.9443	PIK3R3	1
KEGG	hsa04622	RIG-I-like receptor signaling pathway	1/215	70/8135	0.8479	0.9443	0.9443	IKBKE	1
KEGG	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	1/215	70/8135	0.8479	0.9443	0.9443	ATP6V0E1	1
KEGG	hsa05230	Central carbon metabolism in cancer	1/215	70/8135	0.8479	0.9443	0.9443	PIK3R3	1
KEGG	hsa05014	Amyotrophic lateral sclerosis	7/215	364/8135	0.8535	0.9458	0.9458	DCTN5/CYCS/RAB39B/GPX7/SIGMAR1/COX4I2/PIK3R4	7
KEGG	hsa00982	Drug metabolism - cytochrome P450	1/215	72/8135	0.8559	0.9458	0.9458	CYP2E1	1
KEGG	hsa04014	Ras signaling pathway	4/215	232/8135	0.8674	0.9503	0.9503	VEGFB/PIK3R3/PLD1/EGF	4
KEGG	hsa05100	Bacterial invasion of epithelial cells	1/215	77/8135	0.8741	0.9503	0.9503	PIK3R3	1
KEGG	hsa00980	Metabolism of xenobiotics by cytochrome P450	1/215	78/8135	0.8775	0.9503	0.9503	CYP2E1	1
KEGG	hsa04721	Synaptic vesicle cycle	1/215	78/8135	0.8775	0.9503	0.9503	ATP6V0E1	1
KEGG	hsa05135	Yersinia infection	2/215	137/8135	0.8818	0.9503	0.9503	PIK3R3/IRAK1	2
KEGG	hsa04613	Neutrophil extracellular trap formation	3/215	190/8135	0.8834	0.9503	0.9503	PIK3R3/PLCB2/C3	3
KEGG	hsa00983	Drug metabolism - other enzymes	1/215	80/8135	0.8839	0.9503	0.9503	CYP2E1	1
KEGG	hsa05418	Fluid shear stress and atherosclerosis	2/215	139/8135	0.8868	0.9503	0.9503	ACVR1/PIK3R3	2
KEGG	hsa04662	B cell receptor signaling pathway	1/215	82/8135	0.89	0.9503	0.9503	PIK3R3	1
KEGG	hsa04120	Ubiquitin mediated proteolysis	2/215	142/8135	0.8939	0.9508	0.9508	FBXO4/SMURF1	2
KEGG	hsa04144	Endocytosis	4/215	251/8135	0.9037	0.9552	0.9552	EHD4/PLD1/ACAP3/SMURF1	4
KEGG	hsa03040	Spliceosome	2/215	147/8135	0.9047	0.9552	0.9552	HNRNPU/CRNKL1	2
KEGG	hsa05415	Diabetic cardiomyopathy	3/215	203/8135	0.9087	0.9558	0.9558	PIK3R3/PLCB2/COX4I2	3
KEGG	hsa03010	Ribosome	2/215	158/8135	0.9251	0.9695	0.9695	MRPL18/RPS4Y1	2
KEGG	hsa05020	Prion disease	4/215	273/8135	0.9346	0.972	0.972	LAMC1/CYCS/PIK3R3/COX4I2	4
KEGG	hsa04024	cAMP signaling pathway	3/215	221/8135	0.9356	0.972	0.972	ADCY8/PIK3R3/PLD1	3
KEGG	hsa04974	Protein digestion and absorption	1/215	103/8135	0.9377	0.972	0.972	COL6A6	1
KEGG	hsa03013	Nucleocytoplasmic transport	1/215	108/8135	0.9456	0.9766	0.9766	IPO13	1
KEGG	hsa04726	Serotonergic synapse	1/215	115/8135	0.9551	0.9827	0.9827	PLCB2	1
KEGG	hsa04110	Cell cycle	1/215	126/8135	0.9667	0.9846	0.9846	GADD45B	1
KEGG	hsa04380	Osteoclast differentiation	1/215	128/8135	0.9684	0.9846	0.9846	PIK3R3	1
KEGG	hsa04142	Lysosome	1/215	132/8135	0.9717	0.9846	0.9846	GLA	1
KEGG	hsa05203	Viral carcinogenesis	2/215	204/8135	0.9736	0.9846	0.9846	PIK3R3/C3	2
KEGG	hsa05012	Parkinson disease	3/215	266/8135	0.9742	0.9846	0.9846	CYCS/SNCA/COX4I2	3
KEGG	hsa04390	Hippo signaling pathway	1/215	157/8135	0.9857	0.9927	0.9927	AXIN2	1
KEGG	hsa04740	Olfactory transduction	4/215	440/8135	0.9977	0.9998	0.9998	OR2W1/OR1A2/OR10A4/OR2C3	4
KEGG	hsa05206	MicroRNAs in cancer	1/215	310/8135	0.9998	0.9998	0.9998	PIK3R3	1