ONTOLOGY	ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	qvalue	geneID	Count
BP	GO:0006469	negative regulation of protein kinase activity	56/2159	235/18670	8.661e-08	0.0004803	0.000445	DUSP6/HIPK3/ABL1/SPRY2/DUSP1/SPRED1/DUSP5/SPRY4/CDK5RAP3/MLLT1/RGS4/CAV1/LAX1/CDKN1C/TRIB1/WWTR1/HEXIM2/DUSP3/CDKN1B/VPS25/CDKN2D/GSKIP/SOCS5/NR2F2/CEP85/CAMK2N1/CHORDC1/SPRED2/DUSP7/GMFB/SOCS3/ITPRIP/CDKN2C/SH2B3/ERRFI1/PRKAR1A/PAK2/GADD45A/TNFAIP3/GADD45B/RGS2/UBASH3B/RB1/IFNG/HSPB1/CEBPA/EPHB2/PPM1F/DTNBP1/TRIB2/SMYD3/DEPTOR/CDKN2B/DUSP19/PRKAR2A/ADARB1	56
BP	GO:0033673	negative regulation of kinase activity	59/2159	257/18670	1.592e-07	0.0004803	0.000445	DUSP6/HIPK3/ABL1/SPRY2/DUSP1/SPRED1/DUSP5/SPRY4/CDK5RAP3/MLLT1/RGS4/CAV1/LAX1/CDKN1C/TRIB1/WWTR1/HEXIM2/DUSP3/CDKN1B/VPS25/CDKN2D/GSKIP/SOCS5/NR2F2/CEP85/CAMK2N1/CHORDC1/SPRED2/DUSP7/GMFB/SOCS3/ITPRIP/CDKN2C/AJUBA/COX11/SH2B3/ERRFI1/PRKAR1A/PAK2/GADD45A/TNFAIP3/GADD45B/RGS2/UBASH3B/RB1/PIK3IP1/IFNG/HSPB1/CEBPA/EPHB2/PPM1F/DTNBP1/TRIB2/SMYD3/DEPTOR/CDKN2B/DUSP19/PRKAR2A/ADARB1	59
BP	GO:0051348	negative regulation of transferase activity	62/2159	285/18670	5.827e-07	0.001172	0.001086	DUSP6/HIPK3/ABL1/SPRY2/DUSP1/SPRED1/DUSP5/SPRY4/CDK5RAP3/MLLT1/RGS4/CAV1/LAX1/CDKN1C/PARP3/TRIB1/WWTR1/HEXIM2/DUSP3/CDKN1B/VPS25/CDKN2D/GSKIP/SOCS5/NR2F2/CEP85/CAMK2N1/CHORDC1/SPRED2/DUSP7/GMFB/SOCS3/ITPRIP/CDKN2C/AJUBA/COX11/SH2B3/ERRFI1/PRKAR1A/PAK2/GADD45A/TNFAIP3/GADD45B/RGS2/UBASH3B/RB1/PIK3IP1/IFNG/HSPB1/SMAD7/CEBPA/POT1/EPHB2/PPM1F/DTNBP1/TRIB2/SMYD3/DEPTOR/CDKN2B/DUSP19/PRKAR2A/ADARB1	62
BP	GO:0007249	I-kappaB kinase/NF-kappaB signaling	57/2159	269/18670	3.887e-06	0.005862	0.005431	BIRC3/IKBKE/NLRX1/ABL1/RELB/TANK/NDFIP2/TNIP1/NFKBIL1/CFLAR/RIPK2/SLC20A1/IL1RN/IRF3/TAB3/PRKD1/TRIM59/PELI1/F2RL1/TNFSF11/TRAF3IP2/RELA/USP10/TMEM101/MAP3K3/TNFRSF10B/PPM1B/VAPA/CHUK/NLRC3/AJUBA/TNFSF10/IRAK4/UBE2N/ECT2/TNFAIP3/CPNE1/MID2/TLR4/IRAK2/HSPB1/IL36RN/MTDH/TERF2IP/RHOC/ZDHHC13/FYN/TIFAB/TIAF1/GOLT1B/DDX21/BIRC2/SNIP1/ZFAND6/IL36B/IRAK1BP1/TRIM13	57
BP	GO:0010212	response to ionizing radiation	36/2159	147/18670	8.671e-06	0.009012	0.008349	POLG/CCND1/TANK/EGR1/ICAM1/ERCC6/IKBIP/NABP1/CCL7/RFWD3/RAD54L/PAXIP1/DNMT3A/THBD/POLB/HMGA2/ELK1/TP53BP1/BABAM1/YAP1/INIP/ECT2/GADD45A/BCL2L1/HSF1/RAD9A/GTF2H5/HRAS/TOPBP1/POLE3/LIG4/TRIM13/WRN/SWI5/NAMPT/USP28	36
BP	GO:0097193	intrinsic apoptotic signaling pathway	59/2159	289/18670	8.962e-06	0.009012	0.008349	BDKRB2/TNFRSF1B/DDX3X/IKBKE/ABL1/NUPR1/DDIT3/ERCC6/MCL1/CAV1/EPHA2/ZNF385B/PLEKHF1/CXCL12/JMY/ACKR3/BCL2A1/BID/PDK2/PTPMT1/PMAIP1/PPIF/CDKN2D/GSKIP/FNIP2/HIPK1/CASP4/POLB/SGPP1/TNFRSF10B/MLH1/ZNF622/MAP3K5/PLAUR/CASP9/CD44/RRN3/CUL3/JAK2/MUC1/CCAR2/BCL2L1/SNW1/TP63/HSPB1/CD24/MYBBP1A/NDUFS3/APAF1/PPM1F/RAD9A/STYXL1/NME5/HNRNPK/MLLT11/HRAS/DDX5/BCL2L2/USP28	59
BP	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	50/2159	237/18670	1.684e-05	0.01328	0.0123	BIRC3/IKBKE/NLRX1/ABL1/TANK/NDFIP2/TNIP1/CFLAR/RIPK2/SLC20A1/IL1RN/IRF3/TAB3/PRKD1/TRIM59/PELI1/F2RL1/TNFSF11/TRAF3IP2/RELA/USP10/TMEM101/MAP3K3/TNFRSF10B/PPM1B/VAPA/CHUK/NLRC3/AJUBA/TNFSF10/IRAK4/UBE2N/ECT2/TNFAIP3/CPNE1/MID2/TLR4/HSPB1/IL36RN/MTDH/TERF2IP/RHOC/ZDHHC13/FYN/GOLT1B/DDX21/BIRC2/ZFAND6/IL36B/TRIM13	50
BP	GO:0001933	negative regulation of protein phosphorylation	79/2159	429/18670	1.76e-05	0.01328	0.0123	BDKRB2/BDKRB1/DUSP6/HIPK3/ABL1/SPRY2/DUSP1/SPRED1/DUSP5/LIF/JUN/TNIP1/CCNB1/SPRY4/CDK5RAP3/MLLT1/RGS4/SLIT2/CAV1/LAX1/CDKN1C/TRIB1/WWTR1/HEXIM2/DUSP3/F2RL1/CDKN1B/PIP5KL1/VPS25/CDKN2D/PRKCZ/GSKIP/SOCS5/PARD3/NR2F2/CEP85/CAMK2N1/CHORDC1/SPRED2/PDE4D/DUSP7/GMFB/SOCS3/ITPRIP/GPD1L/CDKN2C/SH2B3/ENPP1/RNF149/ERRFI1/PRKAR1A/PAK2/GADD45A/TNFAIP3/GADD45B/RGS2/INPP5F/UBASH3B/RB1/TLR4/IFNG/HSPB1/SMAD7/CEBPA/IMPACT/EPHB2/TERF2IP/PPM1F/DTNBP1/TRIB2/SMYD3/DEPTOR/CRKL/CDKN2B/DUSP19/PRKAR2A/CASC2/ADARB1/EMILIN1	79
BP	GO:0042326	negative regulation of phosphorylation	84/2159	468/18670	2.577e-05	0.01727	0.016	BDKRB2/BDKRB1/DUSP6/HIPK3/ABL1/SPRY2/DUSP1/SPRED1/DUSP5/LIF/JUN/TNIP1/NUPR1/CCNB1/SPRY4/CDK5RAP3/MLLT1/RGS4/SLIT2/CAV1/LAX1/CDKN1C/TRIB1/WWTR1/HEXIM2/DUSP3/F2RL1/CDKN1B/PIP5KL1/VPS25/PPIF/CDKN2D/PRKCZ/GSKIP/SOCS5/PARD3/NR2F2/CEP85/CAMK2N1/CHORDC1/SPRED2/PDE4D/DUSP7/GMFB/SOCS3/ITPRIP/GPD1L/CDKN2C/AJUBA/COX11/SH2B3/ENPP1/RNF149/ERRFI1/PRKAR1A/PAK2/GADD45A/TNFAIP3/GADD45B/RGS2/INPP5F/UBASH3B/RB1/TLR4/PIK3IP1/IFNG/HSPB1/SMAD7/CEBPA/IMPACT/EPHB2/TERF2IP/PPM1F/DTNBP1/TRIB2/SMYD3/DEPTOR/CRKL/CDKN2B/DUSP19/PRKAR2A/CASC2/ADARB1/EMILIN1	84
BP	GO:0006732	coenzyme metabolic process	74/2159	403/18670	3.537e-05	0.01872	0.01735	GPD2/ZBTB7A/NT5E/NUPR1/GCDH/IDH1/RBKS/ACOT7/FAR2/PNPO/LIAS/PDP2/MCCC1/COQ5/GSTO1/HK1/ACACB/GSTZ1/PRKAG1/GSTO2/PDK2/GCH1/DCXR/RAE1/PCCB/RPIA/PPCDC/ELOVL7/MVK/FOXK2/HSD17B8/PANK1/ELOVL6/GPD1L/PCBD2/SLC2A3/AKR1A1/ACOT13/PKM/ACBD6/HMGCL/ADPGK/PARP16/RFK/COQ7/MCEE/PFKP/NUP35/IFNG/RNLS/SLC23A2/SEH1L/DLAT/COQ3/PPTC7/FMO2/NUP98/MDH1B/QDPR/HK2/NUP153/SLC25A32/PFKM/SLC46A1/ELOVL4/NUDT17/MVD/DERA/PDP1/PGLS/ACSL4/NAMPT/IGF1/PPCS	74
BP	GO:0007050	cell cycle arrest	49/2159	237/18670	3.541e-05	0.01872	0.01735	MAP2K6/PRKAB2/CCND1/ABL1/DUSP1/CCNB1/DDIT3/CRLF3/CDK4/CDKN1C/JMY/PRKAG1/TBRG4/CDKN1B/TCF7L2/CDKN2D/ID2/ING4/KMT2E/MAP2K1/PCBP4/CNOT6L/LAMTOR3/CDKN2C/CNOT6/HMGA2/BRINP1/MAGI2/TFDP2/LAMTOR4/MLST8/CDK5R1/MUC1/GADD45A/ZNF268/RB1/IFNG/NOTCH1/MYBBP1A/E2F4/SDE2/CDC25C/IL12A/CDKN2B/CDK6/PRKACA/RRAGC/HRAS/PPM1G	49
BP	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	27/2159	104/18670	3.724e-05	0.01872	0.01735	TNFRSF1B/IKBKE/ABL1/NUPR1/ERCC6/MCL1/EPHA2/CXCL12/ACKR3/BCL2A1/BID/CDKN2D/FNIP2/HIPK1/POLB/MLH1/CASP9/CD44/MUC1/CCAR2/BCL2L1/SNW1/TP63/RAD9A/HNRNPK/BCL2L2/USP28	27
BP	GO:0072331	signal transduction by p53 class mediator	53/2159	267/18670	5.535e-05	0.02569	0.0238	BDKRB2/PRKAB2/SPRED1/NUPR1/CCNB1/TP53RK/CDK5RAP3/ZNF385B/JMY/PRKAG1/PAXIP1/PDK2/CDKN1B/SESN2/PMAIP1/MAPKAPK5/HIPK1/USP10/PHF20/RAD50/ING4/SPRED2/PCBP4/CNOT6L/RPA2/CNOT6/KAT6A/TFDP2/CD44/RRN3/CDK5R1/MUC1/GADD45A/SNW1/TP63/TAF12/MYBBP1A/E2F4/RAD9A/RPA1/CDC25C/RAD17/HNRNPK/HDAC2/ANKRD1/TAF5/PAK1IP1/TAF4B/TOPBP1/DDX5/MTA2/WRN/USP28	53
BP	GO:0071549	cellular response to dexamethasone stimulus	12/2159	30/18670	6.462e-05	0.02629	0.02435	CFLAR/ICAM1/GJB2/AQP1/PCK2/CASP9/ERRFI1/EIF4E/NR3C1/FBXO32/AGTR2/SMYD3	12
BP	GO:0006352	DNA-templated transcription, initiation	50/2159	249/18670	6.536e-05	0.02629	0.02435	FOSL1/CCND1/CBFB/JUN/CCNB1/MED30/TFAM/SUB1/ATF7IP/NR1D2/BRF2/CDK4/WWTR1/PAXIP1/POLR1E/RRN3P1/PSMC2/HEY2/POLR2I/RBPJ/NR4A3/MED16/RRN3/GTF2F2/YAP1/TAF6L/POLR1C/NR3C1/SNW1/POLR2G/NR2F1/TAF12/E2F3/NOTCH1/THRA/GTF2I/NR4A2/SMARCA4/SETX/GTF2H5/MED20/VDR/MED7/NR2C2/TAF5/TAF4B/PGR/NR3C2/TEAD1/BAZ2A	50
BP	GO:0043254	regulation of protein complex assembly	82/2159	467/18670	7.035e-05	0.02653	0.02458	FOSL1/DDX3X/ABL1/VILL/ULK1/PAN2/JUN/ARHGAP28/ICAM1/ARF6/SUB1/ATF7IP/SLIT2/TMOD2/LMO4/JMY/PAN3/BID/PAXIP1/CDKN1B/RHOBTB1/ARPC5L/PMAIP1/PRKCZ/FNIP2/RALB/PSMC2/MPP7/HEY2/STX1A/BBS10/VPS11/ARPC5/GMFB/FMN2/CNOT6L/RPA2/KIF14/NLRC3/CNOT6/AJUBA/PFN4/EVL/ARPC2/MYO1C/RRN3/FCHSD2/MAPRE1/CDK5R1/RICTOR/AIM2/PFN2/ARPC4/ASAP1/IRGM/RB1/TLR4/IFNG/VASP/CPTP/IMPACT/TMOD3/THRA/TRIOBP/RHOC/PREX1/STYXL1/SETX/RPA1/GTF2H5/SEC24B/WASL/CHD1L/BIRC2/RASA1/CDC42EP2/MIEF2/SPTA1/NIN/STXBP1/DHX33/TFIP11	82
BP	GO:0071901	negative regulation of protein serine/threonine kinase activity	33/2159	145/18670	9.622e-05	0.03415	0.03164	DUSP6/HIPK3/ABL1/SPRY2/DUSP1/SPRED1/DUSP5/SPRY4/CDK5RAP3/RGS4/CAV1/LAX1/CDKN1C/HEXIM2/DUSP3/CDKN1B/CDKN2D/NR2F2/CHORDC1/SPRED2/DUSP7/CDKN2C/SH2B3/PRKAR1A/TNFAIP3/RGS2/RB1/HSPB1/CEBPA/DTNBP1/CDKN2B/DUSP19/PRKAR2A	33
BP	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	39/2159	183/18670	0.0001086	0.03638	0.03371	BIRC3/IKBKE/ABL1/NDFIP2/CFLAR/RIPK2/SLC20A1/IL1RN/IRF3/TAB3/PRKD1/PELI1/F2RL1/TNFSF11/TRAF3IP2/RELA/TMEM101/MAP3K3/TNFRSF10B/VAPA/CHUK/AJUBA/TNFSF10/IRAK4/UBE2N/ECT2/MID2/TLR4/IL36RN/MTDH/TERF2IP/RHOC/ZDHHC13/FYN/GOLT1B/DDX21/BIRC2/IL36B/TRIM13	39
BP	GO:1904029	regulation of cyclin-dependent protein kinase activity	26/2159	106/18670	0.0001427	0.04408	0.04084	CCND1/SERTAD1/CCNB1/CDK5RAP3/CCNYL1/CDK4/CDKN1C/HEXIM2/CCNJ/CDKN1B/CDKN2D/NR2F2/ADAM17/CAMK2N1/CDKN2C/CDK5R1/GADD45A/CKS2/TNFAIP3/CKS1B/CEBPA/CCND3/CDC25C/DIRAS3/CDKN2B/CCNT1	26
BP	GO:0097191	extrinsic apoptotic signaling pathway	45/2159	224/18670	0.0001461	0.04408	0.04084	TNFRSF1B/DDX3X/G0S2/CFLAR/ICAM1/MKNK2/PARP2/MCL1/CAV1/TNFRSF10A/BCL2A1/BID/CD27/FEM1B/TCF7L2/DAXX/PMAIP1/RELA/HIPK1/SGPP1/TNFRSF10B/ITPRIP/TRAF1/TNFSF10/CASP9/TNFRSF12A/YAP1/PAK2/HMGB2/JAK2/TNFAIP3/BCL2L1/FGFR1/IFNG/AGTR2/GABARAP/EYA4/IL12A/FYN/DEPTOR/PELI3/MLLT11/BCL2L2/BLOC1S2/IGF1	45
BP	GO:0006284	base-excision repair	14/2159	42/18670	0.0001663	0.04755	0.04405	POLG/HMGA1/ERCC6/PARP2/POLL/POLB/APEX1/RPA2/MPG/HMGA2/FEN1/MUTYH/RPA1/WRN	14
BP	GO:0035914	skeletal muscle cell differentiation	19/2159	68/18670	0.000181	0.04755	0.04405	FOS/SIX1/MAFF/HIVEP3/EGR1/NUPR1/EGR2/NR1D2/AKIRIN1/HLF/BCL9L/SOX8/MEF2D/EOMES/FOXN2/RB1/NOTCH1/KLF5/DDX5	19
BP	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	25/2159	102/18670	0.0001924	0.04755	0.04405	CCND1/SERTAD1/CCNB1/CDK5RAP3/CCNYL1/CDK4/CDKN1C/HEXIM2/CCNJ/CDKN1B/CDKN2D/NR2F2/ADAM17/CDKN2C/CDK5R1/GADD45A/CKS2/TNFAIP3/CKS1B/CEBPA/CCND3/CDC25C/DIRAS3/CDKN2B/CCNT1	25
BP	GO:0071902	positive regulation of protein serine/threonine kinase activity	61/2159	334/18670	0.0001926	0.04755	0.04405	DUSP6/MAP2K6/BMP2/DDX3X/CCND1/DBF4/SPRY2/GHR/DUSP5/CCNB1/GADD45G/ERCC6/RIPK2/CCNYL1/FGF1/TAB3/CDKN1B/TNFSF11/DAXX/MAPKAPK5/RALB/ADAM17/MAP3K3/DVL3/MAP2K1/SHC1/DUSP7/MAP4K5/DVL2/LAMTOR3/MAP3K5/AJUBA/HMGA2/TIAM1/UBE2N/PARP16/MLST8/CDK5R1/JAK2/GADD45A/CKS2/IRGM/GADD45B/FGFR1/TLR4/IFNG/MAP4K3/IRAK2/CKS1B/CD24/PDGFRB/CCND3/ROR2/CRKL/AVPI1/DUSP19/MAGED1/EPHA4/CCNT1/HRAS/IGF1	61
BP	GO:0006367	transcription initiation from RNA polymerase II promoter	39/2159	188/18670	0.000197	0.04755	0.04405	CCND1/CBFB/CCNB1/MED30/SUB1/ATF7IP/NR1D2/CDK4/WWTR1/PAXIP1/PSMC2/HEY2/POLR2I/RBPJ/NR4A3/MED16/GTF2F2/YAP1/TAF6L/NR3C1/SNW1/POLR2G/NR2F1/TAF12/E2F3/NOTCH1/THRA/GTF2I/NR4A2/GTF2H5/MED20/VDR/MED7/NR2C2/TAF5/TAF4B/PGR/NR3C2/TEAD1	39
BP	GO:0035329	hippo signaling	13/2159	38/18670	0.0002107	0.04889	0.04529	AMOTL1/WWC3/WWTR1/MOB1B/TJP1/PJA2/DVL2/MOB1A/AJUBA/FAT4/YAP1/MARK3/TEAD1	13
BP	GO:0051188	cofactor biosynthetic process	59/2159	326/18670	0.0003109	0.06947	0.06436	ZBTB7A/NUPR1/GCDH/ACOT7/PNPO/LIAS/PDP2/COQ5/HK1/ACACB/GSTZ1/COX15/SLC25A38/MMAB/PRKAG1/PDK2/GCH1/NFE2L1/RAE1/ALAS1/PPCDC/CTNS/ELOVL7/FOXK2/HSD17B8/PANK1/ABCB6/ELOVL6/PCBD2/AKR1A1/PKM/ADPGK/PARP16/RFK/COQ7/PFKP/NUP35/IFNG/RNLS/CPOX/SEH1L/DLAT/COQ3/PPTC7/NUP98/QDPR/HK2/FYN/NUP153/PFKM/SLC11A2/ELOVL4/SPTA1/PDP1/ACSL4/MGST2/NAMPT/IGF1/PPCS	59
BP	GO:1901888	regulation of cell junction assembly	22/2159	88/18670	0.0003378	0.06983	0.0647	ABL1/MAP4K4/SLK/CBFB/MACF1/MMP14/LDB1/PEAK1/CAV1/EPHA2/DUSP3/TJP1/BCAS3/SLC9A1/PTK2/SDC4/MYO1C/FLOT1/PPM1F/PRKACA/PHLDB2/TSC1	22
BP	GO:0043583	ear development	43/2159	219/18670	0.0003404	0.06983	0.0647	SIX1/BMP2/MKS1/SPRY2/ATP8B1/OSR2/HES1/FZD2/HOXA1/JAG1/GJB2/RDH10/CDKN1B/OTX1/IFT88/SLC4A7/HEY2/DVL2/SDC4/RBPJ/FGFR2/NR4A3/GSC/LIN7A/FAT4/LRIG3/MPV17/TSHZ1/FGFR1/CCM2/CEBPA/NOTCH1/PDGFRB/EPHB2/TRIOBP/ECE1/ROR2/SHROOM2/SEC24B/TIFAB/EPHA4/GJB6/HOXA2	43
BP	GO:0006997	nucleus organization	29/2159	130/18670	0.0003546	0.06983	0.0647	PPP2R2A/CCNB1/CHMP7/PITPNB/LEMD3/PSME4/TOR1A/SYNE1/TMF1/NFE2L1/GOLM1/VPS4A/SRPK1/AGFG1/TMEM170A/RRN3/AHCTF1/HMGB2/REEP3/PES1/NUP35/SEH1L/ZPR1/NUP98/NUP153/TOR1B/WDR73/PYGO1/WBP2NL	29
BP	GO:0021955	central nervous system neuron axonogenesis	12/2159	35/18670	0.0003588	0.06983	0.0647	EPHB3/FBXO45/SLIT2/B4GALT5/PTK2/B4GALT6/EPHB2/NR4A2/EPHA4/MYCBP2/NIN/ADARB1	12
BP	GO:0043405	regulation of MAP kinase activity	60/2159	337/18670	0.0004319	0.07834	0.07258	DUSP6/MAP2K6/BMP2/HIPK3/SPRY2/DUSP1/GHR/SPRED1/DUSP5/GADD45G/SPRY4/CDK5RAP3/ERCC6/RIPK2/RGS4/FGF1/CAV1/LAX1/TAB3/TRIB1/DUSP3/TNFSF11/DAXX/MAPKAPK5/MAP3K3/DVL3/MAP2K1/SPRED2/SHC1/DUSP7/MAP4K5/DVL2/LAMTOR3/MAP3K5/AJUBA/TIAM1/SH2B3/CDK12/UBE2N/JAK2/GADD45A/GADD45B/RGS2/FGFR1/TLR4/MAP4K3/IRAK2/CD24/PDGFRB/EPHB2/ROR2/DTNBP1/TRIB2/CRKL/AVPI1/DUSP19/MAGED1/EPHA4/HRAS/IGF1	60
BP	GO:0006790	sulfur compound metabolic process	65/2159	372/18670	0.000434	0.07834	0.07258	GHR/MTAP/CHST7/ST3GAL2/B4GALT3/GLCE/GCDH/IDH1/CHST2/ADO/ACOT7/FAR2/LIAS/PDP2/MCCC1/SLC35D1/ALDH5A1/GSTO1/PHGDH/ACACB/GSTZ1/CHST14/GSTO2/ST3GAL1/PDK2/B3GNT2/NFE2L1/PCCB/SLC19A2/B4GALT5/CTNS/ELOVL7/MVK/HSD17B8/ELOVL6/MPST/AKR1A1/ACOT13/ACBD6/BLMH/HMGCL/UGDH/ENPP1/B4GALT6/SULT4A1/MCEE/ABHD14B/CSGALNACT2/IMPAD1/SP1/SLC26A1/DLAT/CHST15/OMD/GLRX2/ACPP/ISCU/ELOVL4/MVD/PDP1/ACSL4/PCYOX1L/MGST2/CHST12/PPCS	65
BP	GO:0010869	regulation of receptor biosynthetic process	9/2159	22/18670	0.0004415	0.07834	0.07258	ITGB3/HOXA5/SEC24A/FURIN/JAK2/IFNG/ANKRD13C/HNRNPK/HDAC2	9
BP	GO:0016050	vesicle organization	58/2159	325/18670	0.0005017	0.08649	0.08013	CHMP7/TAP2/VAPB/STX6/CAV1/PLEKHF1/HOOK2/SEC23IP/RAB32/TMF1/TMEM175/PEF1/TRAPPC6A/VPS25/KLHL12/HOOK3/STX1A/C2CD5/VPS11/VPS4A/AKTIP/RAB11A/SPHK1/SDC4/VAPA/VPS8/SEC24A/HPS4/RAB22A/AGFG1/SNX10/VPS37A/PRKCI/PPP6R1/CUL3/SEC31B/SNAPIN/KIF5B/GOLGA2/TRAPPC2L/DLG4/DNM3/NKD2/AP2M1/GOLPH3/VPS28/RAB8B/PICALM/VAV3/SHROOM2/DTNBP1/VAMP4/LAPTM4B/SEC24B/WASL/GNAI3/STXBP1/BLOC1S2	58
BP	GO:0000188	inactivation of MAPK activity	10/2159	27/18670	0.0005491	0.09179	0.08504	DUSP6/DUSP1/SPRED1/DUSP5/RGS4/CAV1/LAX1/DUSP3/SPRED2/DUSP7	10
BP	GO:0006023	aminoglycan biosynthetic process	26/2159	115/18670	0.0005629	0.09179	0.08504	ABCC5/CHST7/ST3GAL2/B4GALT3/GLCE/CHST2/B3GNT9/SLC35D1/CHST14/ST3GAL1/B3GNT2/NFKB1/B4GALT5/SDC4/UGDH/B4GALT6/HAS1/HS2ST1/CSGALNACT2/PDGFRB/EXT1/CHST15/OMD/EXTL2/HS3ST3A1/CHST12	26
BP	GO:0044272	sulfur compound biosynthetic process	38/2159	192/18670	0.0006228	0.09654	0.08944	MTAP/CHST7/ST3GAL2/B4GALT3/GLCE/GCDH/CHST2/LIAS/PDP2/SLC35D1/GSTO1/ACACB/GSTZ1/CHST14/GSTO2/ST3GAL1/PDK2/B3GNT2/B4GALT5/ELOVL7/HSD17B8/ELOVL6/MPST/AKR1A1/UGDH/B4GALT6/CSGALNACT2/SP1/SLC26A1/DLAT/CHST15/OMD/ELOVL4/PDP1/ACSL4/MGST2/CHST12/PPCS	38
BP	GO:0006304	DNA modification	26/2159	116/18670	0.0006471	0.09654	0.08944	FOS/PARP2/ATF7IP/DNMT1/OTUD4/TET1/PARP3/DNMT3A/ALKBH3/CDADC1/ALKBH5/ASCC1/FTO/HEMK1/KMT2E/APEX1/BEND3/MPG/TDRD1/MUTYH/KDM1B/DMAP1/EXOSC4/PIK3CA/MTA2/BAZ2A	26
BP	GO:0006359	regulation of transcription by RNA polymerase III	9/2159	23/18670	0.0006513	0.09654	0.08944	ZNF143/ZC3H8/BRF2/PRDX5/ELL/POLR3C/CEBPA/NAB2/ICE2	9
BP	GO:0006024	glycosaminoglycan biosynthetic process	25/2159	110/18670	0.0006561	0.09654	0.08944	ABCC5/CHST7/ST3GAL2/B4GALT3/GLCE/CHST2/SLC35D1/CHST14/ST3GAL1/B3GNT2/NFKB1/B4GALT5/SDC4/UGDH/B4GALT6/HAS1/HS2ST1/CSGALNACT2/PDGFRB/EXT1/CHST15/OMD/EXTL2/HS3ST3A1/CHST12	25
BP	GO:0046488	phosphatidylinositol metabolic process	35/2159	174/18670	0.0007376	0.1021	0.09458	MPPE1/SYNJ2/PIGC/PGAP2/MTMR12/PIP5KL1/PLEKHA3/MTMR3/SOCS5/SH3YL1/MTMR9/LCLAT1/PLCB1/SOCS3/IMPA1/SOCS7/SBF1/IMPAD1/INPP5F/PIP4K2A/FAM126A/PIGB/PDGFRB/PIGV/INPP5B/PIK3CD/PIK3C2B/PLA2G12A/MTMR7/PGAP3/CDIPT/PIP5K1A/RUFY1/GALR2/PIK3CA	35
BP	GO:0001655	urogenital system development	58/2159	330/18670	0.0007404	0.1021	0.09458	SIX1/BMP2/LIF/TBX18/OSR2/EGR1/HOXA11/EPHB3/CFLAR/HES1/PTCD2/SLIT2/FGF1/CAT/ARG2/JAG1/CDKN1C/WWTR1/RDH10/FEM1B/CDKN1B/GCNT3/JMJD6/IFT88/SOX8/ID2/SDC4/PGF/MPST/KLHL3/FGFR2/FOXC2/MAGI2/EMX2/CASP9/FAT4/FSTL3/YAP1/MPV17/FGFR1/TP63/SMAD7/NOTCH1/ID3/CD24/PDGFRB/AGTR2/EPHB2/PBX1/APAF1/CRKL/FOXF1/MAGED1/EPHA4/OVOL1/FRAS1/PYGO1/TSC1	58
BP	GO:0006979	response to oxidative stress	75/2159	451/18670	0.0007446	0.1021	0.09458	FOSL1/FOS/ABL1/DUSP1/JUN/MMP14/MSRB2/CFLAR/IDH1/ERCC6/LIAS/MCL1/BRF2/CAT/KPNA4/GJB2/TOR1A/PRKD1/PDK2/AQP1/NDUFA6/GCH1/NFE2L1/EPAS1/UCN/SESN2/RELA/PPIF/GSKIP/ETV5/SESN3/PSIP1/APEX1/ADA/FZD1/CAMKK2/SPHK1/ZNF622/CHUK/COX1/FUT8/TXNIP/MAP3K5/ANGPTL7/NR4A3/OSER1/PPP2CB/MPV17/ECT2/JAK2/ATP13A2/TNFAIP3/PRDX5/SP1/TRPA1/TLR4/HSPB1/PDGFRB/SLC23A2/IMPACT/LANCL1/HSF1/NR4A2/GLRX2/SETX/REST/NME5/FYN/NDUFS2/GPX7/HDAC2/GPX8/ZNF580/WRN/TSC1	75
BP	GO:0032648	regulation of interferon-beta production	14/2159	48/18670	0.0007784	0.1044	0.09669	DDX3X/NLRX1/RELB/RIPK2/IRF3/PPM1B/NLRC3/RNF135/TRAF3/HMGB2/TLR4/POLR3C/FLOT1/NMI	14
BP	GO:2000209	regulation of anoikis	9/2159	24/18670	0.000936	0.1218	0.1128	MCL1/CAV1/PTRH2/PTK2/ZNF304/NOTCH1/MYBBP1A/ANKRD13C/PIK3CA	9
BP	GO:0071479	cellular response to ionizing radiation	18/2159	71/18670	0.0009504	0.1218	0.1128	TANK/EGR1/HMGA2/ELK1/TP53BP1/YAP1/ECT2/GADD45A/BCL2L1/HSF1/RAD9A/GTF2H5/HRAS/POLE3/LIG4/WRN/SWI5/NAMPT	18
BP	GO:0010506	regulation of autophagy	57/2159	327/18670	0.001002	0.1218	0.1128	PRKAB2/ABL1/ULK1/SREBF1/NUPR1/ATP6V1E2/DDIT3/RIPK2/FBXL2/MCL1/LRSAM1/PLEKHF1/TAB3/PRKAG1/PRKD1/EPM2A/SESN2/MTMR3/IFT88/USP10/RALB/SESN3/FOXK2/MTMR9/KDM4A/CAMKK2/PTK2/LAMTOR3/ATG101/ZKSCAN3/LAMTOR4/MLST8/CDK5R1/GOLGA2/ATP13A2/IRGM/MID2/SPTLC2/PIP4K2A/IFNG/CPTP/HSPB1/USP30/ATP6V1B2/MTDH/HK2/SNX5/HERC1/POLDIP2/PRKACA/RRAGC/GNAI3/PIK3CA/TRIM13/TSC1/RAB39B/NAMPT	57
BP	GO:0046677	response to antibiotic	57/2159	327/18670	0.001002	0.1218	0.1128	FOSL1/CCND1/ABL1/DUSP1/JUN/EGR1/ICAM1/ZC3H8/RGS4/CCL7/CAT/KPNA4/GJB2/CD27/DNMT3A/AQP1/CDKN1B/DAXX/RELA/PPIF/POLB/ABAT/SLC9A1/APEX1/ADA/SPHK1/CHUK/TXNIP/MAP3K5/FGFR2/ACTC1/NR4A3/SETDB1/OSER1/CASP9/PPP2CB/DDX11/AACS/ECT2/JAK2/TNFAIP3/BCL2L1/RGS2/TRPA1/ID3/PDGFRB/IMPACT/HSF1/GLRX2/DMAP1/SETX/JAGN1/CYB5R4/FYN/HDAC2/ZNF580/BIRC2	57
BP	GO:0032535	regulation of cellular component size	63/2159	370/18670	0.001042	0.1218	0.1128	ABL1/VILL/MACF1/ADNP/ARHGAP28/ICAM1/ARF6/PEX11A/SLIT2/LRRC8A/CDK4/TMOD2/CXCL12/JMY/PEX11G/PEX11B/AQP1/F2RL1/RHOBTB1/ARPC5L/UCN/WDR36/IFRD1/ARPC5/GMFB/RAB11A/FMN2/RAB22A/PFN4/BDNF/EVL/LAMTOR4/ARPC2/SEMA7A/MYO1C/GDI1/FCHSD2/TNFRSF12A/CDK5R1/RICTOR/RYK/PFN2/ARPC4/ATP13A2/VASP/SLC12A6/TMOD3/AP2M1/TRIOBP/PICALM/PREX1/VAV3/E2F4/WDR1/SEMA4G/DEPTOR/WASL/ZFYVE27/RASA1/CDC42EP2/SPTA1/TSC1/TTL	63
BP	GO:0072001	renal system development	52/2159	293/18670	0.001081	0.1218	0.1128	SIX1/BMP2/LIF/TBX18/OSR2/EGR1/HOXA11/CFLAR/HES1/PTCD2/SLIT2/FGF1/CAT/ARG2/JAG1/CDKN1C/WWTR1/RDH10/GCNT3/JMJD6/IFT88/SOX8/ID2/SDC4/PGF/MPST/KLHL3/FGFR2/FOXC2/MAGI2/EMX2/CASP9/FAT4/FSTL3/YAP1/MPV17/FGFR1/SMAD7/NOTCH1/ID3/CD24/PDGFRB/AGTR2/PBX1/APAF1/FOXF1/MAGED1/EPHA4/OVOL1/FRAS1/PYGO1/TSC1	52
BP	GO:0090398	cellular senescence	19/2159	78/18670	0.001171	0.1218	0.1128	ABL1/HMGA1/RSL1D1/ARG2/MAPKAPK5/BCL6/ID2/MAP3K3/MAP2K1/KAT6A/HMGA2/ZKSCAN3/NSMCE2/YPEL3/CDKN2B/TBX2/CDK6/HRAS/NAMPT	19
BP	GO:0097284	hepatocyte apoptotic process	6/2159	12/18670	0.00118	0.1218	0.1128	CFLAR/ARF6/BID/DNMT3A/BCL2L1/RB1	6
BP	GO:0045445	myoblast differentiation	20/2159	84/18670	0.001193	0.1218	0.1128	DDIT3/HINFP/JAG1/AKIRIN1/EID2B/TCF7L2/EPAS1/SOX8/IFRD1/PLCB1/BOC/RBPJ/MAP3K5/RB1/NOTCH1/ID3/REST/TBX2/DDX5/IGF1	20
BP	GO:0033108	mitochondrial respiratory chain complex assembly	22/2159	96/18670	0.001197	0.1218	0.1128	TFAM/NDUFV2/TIMMDC1/COA5/NDUFA6/OXA1L/NDUFB5/BCS1L/FOXRED1/UQCC1/NDUFAF3/NDUFAF4/TMEM126B/SAMM50/NDUFS3/TTC19/UQCR10/NDUFV1/NDUFS2/NDUFB10/NDUFA11/SURF1	22
BP	GO:0034333	adherens junction assembly	21/2159	90/18670	0.001201	0.1218	0.1128	ABL1/MAP4K4/SLK/MACF1/MMP14/LDB1/ITGA2/PEAK1/DUSP3/HIPK1/BCAS3/SLC9A1/PTK2/SDC4/AJUBA/TRIP6/SMAD7/PPM1F/PIP5K1A/PHLDB2/TSC1	21
BP	GO:0032608	interferon-beta production	14/2159	50/18670	0.001213	0.1218	0.1128	DDX3X/NLRX1/RELB/RIPK2/IRF3/PPM1B/NLRC3/RNF135/TRAF3/HMGB2/TLR4/POLR3C/FLOT1/NMI	14
BP	GO:0035970	peptidyl-threonine dephosphorylation	7/2159	16/18670	0.001213	0.1218	0.1128	DUSP1/DUSP5/PPM1B/PPP2CB/PPM1F/PDP1/PPM1G	7
BP	GO:0033865	nucleoside bisphosphate metabolic process	29/2159	140/18670	0.001252	0.1218	0.1128	HDDC3/GCDH/ACOT7/FAR2/PDP2/ACACB/GSTZ1/PDK2/PPCDC/ELOVL7/MVK/HSD17B8/PANK1/ELOVL6/ACOT13/ACBD6/HMGCL/ENPP1/SULT4A1/MCEE/ABHD14B/IMPAD1/SLC26A1/DLAT/ELOVL4/MVD/PDP1/ACSL4/PPCS	29
BP	GO:0033875	ribonucleoside bisphosphate metabolic process	29/2159	140/18670	0.001252	0.1218	0.1128	HDDC3/GCDH/ACOT7/FAR2/PDP2/ACACB/GSTZ1/PDK2/PPCDC/ELOVL7/MVK/HSD17B8/PANK1/ELOVL6/ACOT13/ACBD6/HMGCL/ENPP1/SULT4A1/MCEE/ABHD14B/IMPAD1/SLC26A1/DLAT/ELOVL4/MVD/PDP1/ACSL4/PPCS	29
BP	GO:0034032	purine nucleoside bisphosphate metabolic process	29/2159	140/18670	0.001252	0.1218	0.1128	HDDC3/GCDH/ACOT7/FAR2/PDP2/ACACB/GSTZ1/PDK2/PPCDC/ELOVL7/MVK/HSD17B8/PANK1/ELOVL6/ACOT13/ACBD6/HMGCL/ENPP1/SULT4A1/MCEE/ABHD14B/IMPAD1/SLC26A1/DLAT/ELOVL4/MVD/PDP1/ACSL4/PPCS	29
BP	GO:0021952	central nervous system projection neuron axonogenesis	9/2159	25/18670	0.001314	0.1218	0.1128	EPHB3/FBXO45/SLIT2/EPHB2/NR4A2/EPHA4/MYCBP2/NIN/ADARB1	9
BP	GO:0045333	cellular respiration	37/2159	193/18670	0.001339	0.1218	0.1128	GPD2/CCNB1/ETFB/IDH1/SLC25A22/CAT/ALDH5A1/NDUFV2/COX15/NOA1/BID/NDUFA6/TBRG4/ACO1/UCN/OXA1L/NDUFB5/CISD1/COX1/NR4A3/IDH3A/IFNG/PRDM16/SLC25A25/MYBBP1A/NDUFS3/DLAT/UQCR10/MDH1B/NDUFV1/NDUFS2/ISCU/NDUFB10/NDUFA11/SURF1/PIK3CA/D2HGDH	37
BP	GO:0009108	coenzyme biosynthetic process	47/2159	261/18670	0.00134	0.1218	0.1128	ZBTB7A/NUPR1/GCDH/ACOT7/PNPO/LIAS/PDP2/COQ5/HK1/ACACB/GSTZ1/PRKAG1/PDK2/GCH1/RAE1/PPCDC/ELOVL7/FOXK2/HSD17B8/PANK1/ELOVL6/PCBD2/AKR1A1/PKM/ADPGK/PARP16/RFK/COQ7/PFKP/NUP35/IFNG/RNLS/SEH1L/DLAT/COQ3/PPTC7/NUP98/QDPR/HK2/NUP153/PFKM/ELOVL4/PDP1/ACSL4/NAMPT/IGF1/PPCS	47
BP	GO:0031334	positive regulation of protein complex assembly	48/2159	268/18670	0.001349	0.1218	0.1128	FOSL1/PAN2/JUN/ICAM1/ARF6/SUB1/JMY/PAN3/BID/PAXIP1/CDKN1B/RHOBTB1/ARPC5L/PMAIP1/FNIP2/PSMC2/MPP7/ARPC5/GMFB/FMN2/CNOT6L/RPA2/CNOT6/AJUBA/EVL/ARPC2/MYO1C/FCHSD2/MAPRE1/CDK5R1/RICTOR/AIM2/PFN2/ARPC4/ASAP1/TLR4/IFNG/VASP/RHOC/SETX/RPA1/GTF2H5/WASL/CHD1L/CDC42EP2/MIEF2/NIN/DHX33	48
BP	GO:0010332	response to gamma radiation	15/2159	56/18670	0.001352	0.1218	0.1128	POLG/EGR1/ERCC6/CCL7/POLB/ELK1/YAP1/BCL2L1/HSF1/GTF2H5/HRAS/POLE3/LIG4/TRIM13/WRN	15
BP	GO:0060113	inner ear receptor cell differentiation	15/2159	56/18670	0.001352	0.1218	0.1128	MKS1/ATP8B1/HES1/FZD2/JAG1/IFT88/SLC4A7/HEY2/SDC4/RBPJ/FAT4/FGFR1/NOTCH1/TRIOBP/SEC24B	15
BP	GO:0071548	response to dexamethasone	12/2159	40/18670	0.001387	0.123	0.114	CFLAR/ICAM1/GJB2/AQP1/PCK2/CASP9/ERRFI1/EIF4E/NR3C1/FBXO32/AGTR2/SMYD3	12
BP	GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway	11/2159	35/18670	0.001428	0.1233	0.1142	BIRC3/MAP2K6/RIPK2/TAB3/RELA/UBE2N/TNFAIP3/IRGM/TLR4/IRAK2/BIRC2	11
BP	GO:0045787	positive regulation of cell cycle	65/2159	389/18670	0.00143	0.1233	0.1142	FOSL1/DDX3X/CCND1/ABL1/DBF4/CCNB1/HES1/CCNYL1/CRLF3/CDK4/DUSP3/CDKN1B/ID2/ADAM17/KMT2E/APEX1/PLCB1/PCBP4/EREG/RAB11A/SPHK1/GPSM2/CNOT6L/KIF14/FGFR2/CNOT6/HMGA2/NR4A3/C6orf89/TFDP2/FEN1/GIPC1/NSMCE2/CUL3/CDK5R1/DDX11/ECT2/MUC1/GADD45A/CKS2/ZNF268/EIF4E/MTA3/RAD51C/FGFR1/CEP120/RB1/CKS1B/PDGFRB/MYBBP1A/TMOD3/HSF1/CCND3/PBX1/E2F4/CDC25C/RAD21/OVOL1/PCID2/CCNT1/CDC7/POLDIP2/PRKACA/TTL/IGF1	65
BP	GO:0007265	Ras protein signal transduction	73/2159	448/18670	0.001529	0.1236	0.1145	ABL1/SPRY2/MAP4K4/RASA2/ARHGEF9/CTNNAL1/JUN/SPRY4/ARF6/CCDC125/DNMT1/RAB32/PRKD1/F2RL1/RHOBTB1/MAPKAPK5/RAB33A/BCL6/RALB/ARHGDIA/SHC1/RHOG/APOC3/RAB11A/RAB30/GPSM2/RAB37/CHUK/KIF14/KCTD13/RAB22A/PHACTR4/TIAM1/NRAS/RAB9B/SETDB1/GDI1/ZNF304/CUL3/PPP2CB/RAPGEF6/ECT2/JAK2/RB1/CDC42SE1/PDPN/STMN3/RAB23/NOTCH1/PDGFRB/RHOQ/EPHB2/RHOC/RAB8B/STAMBP/PREX1/GNA12/VAV3/FLOT1/STK19/MCF2L2/GPR20/MYO9B/CRKL/RGL2/RASA1/CDC42EP2/KCTD10/HRAS/NISCH/RAB39B/USP28/IGF1	73
BP	GO:0009314	response to radiation	73/2159	448/18670	0.001529	0.1236	0.1145	FOS/POLG/CCND1/DUSP1/TANK/SLC24A1/ZBTB1/JUN/EGR1/ICAM1/ERCC6/PER3/IKBIP/NABP1/HOXA1/CCL7/CAT/BEST1/CXCL12/RFWD3/UBE4B/RAD54L/PAXIP1/DNMT3A/AQP1/RELA/CDKN2D/THBD/POLB/ID2/PRIMPOL/DEAF1/CTNS/REEP6/NPTN/CACNA2D4/GPR88/HMGA2/ELK1/TP53BP1/FEN1/CASP9/BABAM1/YAP1/INIP/CIRBP/ECT2/PPEF1/CCAR2/GADD45A/BCL2L1/MAP4K3/IMPACT/HSF1/C9orf116/ST20/JUNB/E2F4/SDE2/RAD9A/IL12A/GTF2H5/ELOVL4/HRAS/TOPBP1/POLE3/LIG4/TRIM13/WRN/CRY1/SWI5/NAMPT/USP28	73
BP	GO:0033866	nucleoside bisphosphate biosynthetic process	17/2159	68/18670	0.001536	0.1236	0.1145	GCDH/ACOT7/PDP2/ACACB/GSTZ1/PDK2/PPCDC/ELOVL7/HSD17B8/PANK1/ELOVL6/SLC26A1/DLAT/ELOVL4/PDP1/ACSL4/PPCS	17
BP	GO:0034030	ribonucleoside bisphosphate biosynthetic process	17/2159	68/18670	0.001536	0.1236	0.1145	GCDH/ACOT7/PDP2/ACACB/GSTZ1/PDK2/PPCDC/ELOVL7/HSD17B8/PANK1/ELOVL6/SLC26A1/DLAT/ELOVL4/PDP1/ACSL4/PPCS	17
BP	GO:0034033	purine nucleoside bisphosphate biosynthetic process	17/2159	68/18670	0.001536	0.1236	0.1145	GCDH/ACOT7/PDP2/ACACB/GSTZ1/PDK2/PPCDC/ELOVL7/HSD17B8/PANK1/ELOVL6/SLC26A1/DLAT/ELOVL4/PDP1/ACSL4/PPCS	17
BP	GO:2000737	negative regulation of stem cell differentiation	8/2159	21/18670	0.001599	0.1254	0.1162	TRIM6/HES1/LBH/JAG1/CDK12/YAP1/NOTCH1/REST	8
BP	GO:0001503	ossification	66/2159	398/18670	0.001607	0.1254	0.1162	BMP2/ATP2B1/RSL1D1/MINPP1/CBFB/MN1/OSR2/MMP14/TWIST2/GDF5/ASF1A/EGR2/CAT/EPHA2/JAG1/WWTR1/CLIC1/PRKD1/TNFSF11/SOX8/PSMC2/ACVR2A/ID2/SATB2/FZD1/TUFT1/PTK2/MEF2D/RBPJ/FGFR2/FOXC2/SNX10/SEMA7A/ENPP1/FAT4/HSPE1/FSTL3/INTU/FBXL15/IMPAD1/PTHLH/TP63/CEBPA/NOTCH1/NAB2/ID3/MYBBP1A/DHRS3/EXT1/THRA/ROR2/OMD/PBX1/JUNB/REST/SH3PXD2B/DDX21/CDK6/HOXA2/PRKACA/TMEM119/DDX5/KREMEN2/TOB2/NPR2/IGF1	66
BP	GO:0048013	ephrin receptor signaling pathway	20/2159	86/18670	0.001622	0.1254	0.1162	EPHB3/EPHA2/YES1/ARPC5/SIPA1L1/PTK2/RBPJ/TIAM1/ARPC2/CDK5R1/AP2A2/ARPC4/AP2M1/EPHB2/VAV3/FYN/WASL/EPHA4/RASA1/HRAS	20
BP	GO:0051092	positive regulation of NF-kappaB transcription factor activity	30/2159	149/18670	0.00167	0.1258	0.1166	ZBTB7A/CFLAR/NFKB2/ICAM1/RIPK2/CAT/CAV1/TAB3/PRKD1/NFKB1/TNFSF11/RELA/PRKCZ/RHEBL1/SPHK1/CHUK/TRAF1/IRAK4/UBE2N/PRKCI/AIM2/MID2/TLR4/IRAK2/MTDH/TERF2IP/FLOT1/LRRFIP1/DHX33/TRIM13	30
BP	GO:0006338	chromatin remodeling	35/2159	182/18670	0.001681	0.1258	0.1166	BAZ1A/HMGA1/ZBTB1/ZBTB7A/SPTY2D1/ANP32E/CHD1/SMARCA1/TOP1/CENPN/PSME4/DAXX/CENPO/SCMH1/SATB2/KDM4A/VPS72/HMGA2/ACTR6/TAF6L/HMGB2/ARID1B/TP63/RB1/TADA2A/CENPU/BAZ2B/SMARCA4/DMAP1/SUV39H2/HDAC2/CHD1L/POLE3/MTA2/BAZ2A	35
BP	GO:0001822	kidney development	49/2159	278/18670	0.001715	0.1258	0.1166	SIX1/BMP2/LIF/OSR2/EGR1/HOXA11/CFLAR/HES1/PTCD2/SLIT2/FGF1/CAT/ARG2/JAG1/CDKN1C/WWTR1/RDH10/GCNT3/JMJD6/IFT88/SOX8/ID2/SDC4/PGF/MPST/KLHL3/FGFR2/FOXC2/MAGI2/CASP9/FAT4/FSTL3/YAP1/MPV17/FGFR1/SMAD7/NOTCH1/ID3/CD24/PDGFRB/AGTR2/PBX1/APAF1/MAGED1/EPHA4/OVOL1/FRAS1/PYGO1/TSC1	49
BP	GO:0045444	fat cell differentiation	41/2159	223/18670	0.001759	0.1258	0.1166	BMP2/CCND1/SREBF1/ZBTB7A/RUNX1T1/CCDC71L/DDIT3/HES1/WDFY2/EGR2/PEX11A/JAG1/ARL4A/MEDAG/WWTR1/AAMDC/TCF7L2/SOX8/ID2/FTO/PLCB1/IL11/TBL1XR1/TGFB1I1/CBY1/HMGA2/NR4A3/ENPP1/NOC3L/AACS/ARL6/RGS2/ALDH6A1/PRDM16/ATF5/BBS2/CEBPA/NR4A2/KLF5/TRIB2/SH3PXD2B	41
BP	GO:0032800	receptor biosynthetic process	9/2159	26/18670	0.001805	0.1258	0.1166	ITGB3/HOXA5/SEC24A/FURIN/JAK2/IFNG/ANKRD13C/HNRNPK/HDAC2	9
BP	GO:0030166	proteoglycan biosynthetic process	17/2159	69/18670	0.001823	0.1258	0.1166	CHST7/GLCE/SLC35D1/CHST14/TCF7L2/CHST10/UGDH/FOXL1/HS2ST1/FAM20B/CSGALNACT2/EXT1/CHST15/EXTL2/HS3ST3A1/CHST12/IGF1	17
BP	GO:0045931	positive regulation of mitotic cell cycle	32/2159	163/18670	0.001838	0.1258	0.1166	DDX3X/CCND1/ABL1/CCNB1/HES1/CDK4/DUSP3/ADAM17/KMT2E/APEX1/PLCB1/EREG/RAB11A/SPHK1/NSMCE2/CUL3/EIF4E/MTA3/RAD51C/FGFR1/RB1/PDGFRB/TMOD3/HSF1/CCND3/PBX1/CDC25C/PCID2/CDC7/POLDIP2/TTL/IGF1	32
BP	GO:0035872	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	11/2159	36/18670	0.001845	0.1258	0.1166	BIRC3/MAP2K6/RIPK2/TAB3/RELA/UBE2N/TNFAIP3/IRGM/TLR4/IRAK2/BIRC2	11
BP	GO:2000811	negative regulation of anoikis	7/2159	17/18670	0.001858	0.1258	0.1166	MCL1/CAV1/PTRH2/PTK2/ZNF304/NOTCH1/PIK3CA	7
BP	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity	10/2159	31/18670	0.001872	0.1258	0.1166	CCND1/CCNB1/CCNYL1/CDKN1B/ADAM17/CDK5R1/CKS2/CKS1B/CCND3/CCNT1	10
BP	GO:0007045	cell-substrate adherens junction assembly	19/2159	81/18670	0.001884	0.1258	0.1166	ABL1/MAP4K4/SLK/MACF1/MMP14/LDB1/ITGA2/PEAK1/DUSP3/BCAS3/SLC9A1/PTK2/SDC4/AJUBA/TRIP6/PPM1F/PIP5K1A/PHLDB2/TSC1	19
BP	GO:0048041	focal adhesion assembly	19/2159	81/18670	0.001884	0.1258	0.1166	ABL1/MAP4K4/SLK/MACF1/MMP14/LDB1/ITGA2/PEAK1/DUSP3/BCAS3/SLC9A1/PTK2/SDC4/AJUBA/TRIP6/PPM1F/PIP5K1A/PHLDB2/TSC1	19
BP	GO:0006914	autophagy	79/2159	496/18670	0.001928	0.1258	0.1166	PRKAB2/ABL1/ULK1/SREBF1/MAP1S/NUPR1/ATP6V1E2/DDIT3/RNF185/RIPK2/FBXL2/MCL1/LRSAM1/PLEKHF1/TAB3/PRKAG1/PRKD1/EPM2A/SESN2/VPS25/MTMR3/IFT88/USP10/RALB/SESN3/ATG4C/FOXK2/VPS11/MTMR9/VPS4A/KDM4A/CAMKK2/PTK2/LAMTOR3/TEX264/ATG101/KLHL3/GABARAPL1/MFN1/ZKSCAN3/LAMTOR4/VPS37A/TM9SF1/MLST8/SNAPIN/CDK5R1/GOLGA2/ATP13A2/IRGM/MID2/SPTLC2/PIP4K2A/IFNG/CPTP/RAB23/HSPB1/VPS51/USP30/ATP6V1B2/GABARAP/MTDH/VPS28/TECPR1/PIK3C2B/TMEM41B/HK2/SNX5/CLN3/EVA1A/HERC1/POLDIP2/PRKACA/RRAGC/GNAI3/PIK3CA/TRIM13/TSC1/RAB39B/NAMPT	79
BP	GO:0061919	process utilizing autophagic mechanism	79/2159	496/18670	0.001928	0.1258	0.1166	PRKAB2/ABL1/ULK1/SREBF1/MAP1S/NUPR1/ATP6V1E2/DDIT3/RNF185/RIPK2/FBXL2/MCL1/LRSAM1/PLEKHF1/TAB3/PRKAG1/PRKD1/EPM2A/SESN2/VPS25/MTMR3/IFT88/USP10/RALB/SESN3/ATG4C/FOXK2/VPS11/MTMR9/VPS4A/KDM4A/CAMKK2/PTK2/LAMTOR3/TEX264/ATG101/KLHL3/GABARAPL1/MFN1/ZKSCAN3/LAMTOR4/VPS37A/TM9SF1/MLST8/SNAPIN/CDK5R1/GOLGA2/ATP13A2/IRGM/MID2/SPTLC2/PIP4K2A/IFNG/CPTP/RAB23/HSPB1/VPS51/USP30/ATP6V1B2/GABARAP/MTDH/VPS28/TECPR1/PIK3C2B/TMEM41B/HK2/SNX5/CLN3/EVA1A/HERC1/POLDIP2/PRKACA/RRAGC/GNAI3/PIK3CA/TRIM13/TSC1/RAB39B/NAMPT	79
BP	GO:0016569	covalent chromatin modification	76/2159	474/18670	0.001939	0.1258	0.1166	BAZ1A/KDM7A/SREBF1/LIF/CCNB1/LDB1/TAF5L/JADE1/SUDS3/RNF20/ATF7IP/KANSL1L/DNMT1/CHD1/TET1/PCGF3/PAXIP1/PRKD1/DNMT3A/MRGBP/SETD1B/JMJD6/DOT1L/CPA4/UCN/PRMT9/BCL6/PHF20/MSL1/ING4/KMT2E/JADE3/KDM4A/BEND3/MIER2/TBL1XR1/DPF2/KAT6A/HMGA2/KDM3B/C6orf89/SETDB1/PHF1/UBE2N/ZNF304/TAF6L/JAK2/KANSL1/MUC1/MTA3/ASH2L/KDM1B/SNW1/TADA2A/PRDM16/TAF12/USP21/AKAP8/PAXBP1/PPM1F/DMAP1/WDR5B/REST/EYA4/SUV39H2/SMYD3/SETD3/HDAC2/TRIM16/TAF5/HAT1/SUPT7L/MSL3/POLE3/MTA2/BAZ2A	76
BP	GO:0048711	positive regulation of astrocyte differentiation	6/2159	13/18670	0.001978	0.1267	0.1174	BMP2/LIF/HES1/CLCF1/ID2/NOTCH1	6
BP	GO:0006473	protein acetylation	38/2159	204/18670	0.001995	0.1267	0.1174	BAZ1A/FAM161A/HINT2/LIF/NUPR1/LDB1/TAF5L/JADE1/KANSL1L/PAXIP1/MRGBP/CPA4/PHF20/MSL1/ING4/JADE3/NAA20/EHHADH/SPHK1/BEND3/DPF2/KAT6A/TAF6L/KANSL1/MUC1/TADA2A/TAF12/NATD1/TERF2IP/DMAP1/HDAC2/TRIM16/POR/TAF5/HAT1/SUPT7L/MSL3/POLE3	38
BP	GO:0018212	peptidyl-tyrosine modification	61/2159	366/18670	0.00209	0.1314	0.1217	MAP2K6/ABL1/GHR/LIF/EPHB3/ADNP/ITGB3/HES1/ICAM1/ERCC6/RIPK2/PEAK1/CLK4/CAV1/EPHA2/CLCF1/YES1/VPS25/PRKCZ/SOCS5/TEC/TYK2/FGF7/ADAM17/MAP2K1/NEK1/SHC1/SOCS3/HBEGF/EREG/IL11/CAMKK2/PTK2/DVL2/FGFR2/BDNF/SH2B3/CD44/ERRFI1/RICTOR/RYK/PAK2/JAK2/IL22RA2/DSTYK/FGFR1/INPP5F/DLG4/IFNG/CD24/PDGFRB/HSF1/EPHB2/ROR2/IL12A/FYN/HDAC2/SCYL1/EPHA4/TTL/IGF1	61
BP	GO:0034599	cellular response to oxidative stress	52/2159	302/18670	0.002131	0.1323	0.1226	FOS/ABL1/JUN/MSRB2/CFLAR/MCL1/BRF2/CAT/GJB2/PRKD1/PDK2/AQP1/GCH1/NFE2L1/EPAS1/SESN2/RELA/PPIF/GSKIP/ETV5/APEX1/FZD1/CAMKK2/SPHK1/ZNF622/CHUK/FUT8/MAP3K5/NR4A3/OSER1/MPV17/ECT2/JAK2/ATP13A2/TNFAIP3/PRDX5/TLR4/HSPB1/IMPACT/LANCL1/HSF1/NR4A2/GLRX2/SETX/REST/NME5/FYN/GPX7/HDAC2/GPX8/ZNF580/TSC1	52
BP	GO:0016570	histone modification	73/2159	454/18670	0.002182	0.1323	0.1226	BAZ1A/KDM7A/SREBF1/LIF/CCNB1/LDB1/TAF5L/JADE1/SUDS3/RNF20/KANSL1L/DNMT1/TET1/PCGF3/PAXIP1/PRKD1/MRGBP/SETD1B/JMJD6/DOT1L/CPA4/UCN/PRMT9/BCL6/PHF20/MSL1/ING4/KMT2E/JADE3/KDM4A/BEND3/MIER2/TBL1XR1/DPF2/KAT6A/HMGA2/KDM3B/C6orf89/SETDB1/PHF1/UBE2N/ZNF304/TAF6L/JAK2/KANSL1/MUC1/MTA3/ASH2L/KDM1B/SNW1/TADA2A/PRDM16/TAF12/USP21/AKAP8/PAXBP1/PPM1F/DMAP1/WDR5B/REST/EYA4/SUV39H2/SMYD3/SETD3/HDAC2/TRIM16/TAF5/HAT1/SUPT7L/MSL3/POLE3/MTA2/BAZ2A	73
BP	GO:0042278	purine nucleoside metabolic process	18/2159	76/18670	0.002186	0.1323	0.1226	HDDC3/MTAP/NT5E/GMPR2/NUDT18/IMPDH2/OARD1/ADA/PNP/AMPD3/MFN1/RAB23/RHOQ/ACPP/NME5/NME3/NME6/GNAI3	18
BP	GO:0051056	regulation of small GTPase mediated signal transduction	57/2159	338/18670	0.002193	0.1323	0.1226	ABL1/SPRY2/MAP4K4/ARHGAP19/RASA2/ARHGEF9/SPRY4/ARHGAP28/ARF6/CCDC125/SYDE2/SLIT2/F2RL1/RHOBTB1/STARD8/BCL6/ARHGDIA/SIPA1L1/SIPA1L3/SHC1/RHOG/APOC3/FRMD7/ARHGAP22/KIF14/KCTD13/TIAM1/GDI1/CUL3/PPP2CB/ECT2/JAK2/SRGAP1/CDC42SE1/STMN3/NOTCH1/PDGFRB/RHOQ/INPP5B/EPHB2/RHOC/SIPA1L2/STAMBP/PREX1/VAV3/FLOT1/STK19/MCF2L2/GPR20/MYO9B/CRKL/RGL2/RASA1/KCTD10/HRAS/SIPA1/IGF1	57
BP	GO:0048839	inner ear development	36/2159	192/18670	0.002296	0.1371	0.127	SIX1/BMP2/MKS1/SPRY2/ATP8B1/HES1/FZD2/HOXA1/JAG1/GJB2/CDKN1B/OTX1/IFT88/SLC4A7/HEY2/DVL2/SDC4/RBPJ/FGFR2/NR4A3/LIN7A/FAT4/LRIG3/MPV17/FGFR1/CCM2/CEBPA/NOTCH1/PDGFRB/EPHB2/TRIOBP/ROR2/SEC24B/TIFAB/EPHA4/GJB6	36
BP	GO:0098727	maintenance of cell number	31/2159	159/18670	0.002399	0.1419	0.1315	LIF/FOXP1/MED30/LDB1/HES1/LBH/JAG1/TET1/SMC3/ELAVL1/BCL9L/HOOK3/POLR2I/VPS72/RBPJ/EOMES/HMGA2/SRRT/YAP1/EIF4E/TP63/POLR2G/PRDM16/NOTCH1/PBX1/PELO/REST/MED7/ZC3H13/LIG4/IGF1	31
BP	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	9/2159	27/18670	0.002433	0.1425	0.132	CCND1/CCNB1/CDK4/RAB11A/MTA3/RAD51C/PBX1/CDC25C/CDC7	9
BP	GO:0042254	ribosome biogenesis	51/2159	297/18670	0.002476	0.1436	0.1331	DDX3X/RSL1D1/DIMT1/ZNF593/NOL8/LYAR/BRIX1/RPS24/NIP7/NVL/WDR36/UTP3/RRP15/DROSHA/ESF1/EXOSC8/RRNAD1/ZNF622/HEATR3/LSM6/ZNHIT6/ZNF658/FAM207A/RRN3/MPHOSPH6/RIOK1/PES1/BYSL/NOP10/XPO1/SURF6/MYBBP1A/UTP15/GNL2/PIH1D2/MRPL11/RCL1/MRPL10/CEBPZ/URB2/NAF1/NOP16/GTF2H5/NOM1/EXOSC4/DDX21/GEMIN4/PA2G4/PAK1IP1/TSC1/EXOSC10	51
BP	GO:0072073	kidney epithelium development	28/2159	140/18670	0.002588	0.1487	0.1377	SIX1/BMP2/LIF/HOXA11/HES1/SLIT2/FGF1/CAT/ARG2/JAG1/WWTR1/SOX8/SDC4/PGF/KLHL3/FGFR2/FOXC2/MAGI2/FAT4/YAP1/FGFR1/SMAD7/NOTCH1/CD24/AGTR2/PBX1/MAGED1/EPHA4	28
BP	GO:2001020	regulation of response to DNA damage stimulus	39/2159	214/18670	0.002635	0.1487	0.1377	ABL1/SPRED1/ERCC6/MCL1/IER3/CXCL12/PARP3/RFWD3/ACKR3/BID/PAXIP1/FEM1B/PMAIP1/CDKN2D/SPRED2/FMN2/RPA2/FIGN/HMGA2/NSMCE1/TP53BP1/CASP9/KLHL15/CD44/UBE2N/BABAM1/DDX11/MUC1/CCAR2/BCL2L1/HSF1/TERF2IP/RAD9A/EYA4/HNRNPK/ANKRD1/DDX5/CRY1/TFIP11	39
BP	GO:1901796	regulation of signal transduction by p53 class mediator	34/2159	180/18670	0.002637	0.1487	0.1377	BDKRB2/PRKAB2/SPRED1/TP53RK/CDK5RAP3/JMY/PRKAG1/PMAIP1/MAPKAPK5/HIPK1/PHF20/RAD50/SPRED2/RPA2/KAT6A/CD44/RRN3/CDK5R1/MUC1/TP63/TAF12/RAD9A/RPA1/RAD17/HNRNPK/HDAC2/ANKRD1/TAF5/PAK1IP1/TAF4B/TOPBP1/DDX5/MTA2/WRN	34
BP	GO:0000724	double-strand break repair via homologous recombination	27/2159	134/18670	0.002738	0.152	0.1408	RECQL/NABP1/RFWD3/RAD54L/POLL/RAD50/MCM9/FAN1/RAD51D/RPA2/EXD2/FIGN/RAD54B/NSMCE1/TP53BP1/FEN1/NSMCE2/KLHL15/UBE2N/RAD51C/MCMDC2/TERF2IP/RPA1/HELQ/CDC7/WRN/SWI5	27
BP	GO:0018108	peptidyl-tyrosine phosphorylation	60/2159	363/18670	0.002746	0.152	0.1408	MAP2K6/ABL1/GHR/LIF/EPHB3/ADNP/ITGB3/HES1/ICAM1/ERCC6/RIPK2/PEAK1/CLK4/CAV1/EPHA2/CLCF1/YES1/VPS25/PRKCZ/SOCS5/TEC/TYK2/FGF7/ADAM17/MAP2K1/NEK1/SHC1/SOCS3/HBEGF/EREG/IL11/CAMKK2/PTK2/DVL2/FGFR2/BDNF/SH2B3/CD44/ERRFI1/RICTOR/RYK/PAK2/JAK2/IL22RA2/DSTYK/FGFR1/INPP5F/DLG4/IFNG/CD24/PDGFRB/HSF1/EPHB2/ROR2/IL12A/FYN/HDAC2/SCYL1/EPHA4/IGF1	60
BP	GO:2001252	positive regulation of chromosome organization	33/2159	174/18670	0.002824	0.1529	0.1417	SREBF1/LIF/CCNB1/RNF20/ATF7IP/DNMT1/TET1/PAXIP1/PRKD1/MAPKAPK5/BCL6/RAD50/KMT2E/PARN/C6orf89/SETDB1/PHF1/FEN1/NSMCE2/UBE2N/ZNF304/CUL3/DDX11/MUC1/SNW1/RB1/TADA2A/POT1/AKAP8/PAXBP1/NAF1/RAD21/LIG4	33
BP	GO:0051893	regulation of focal adhesion assembly	15/2159	60/18670	0.002838	0.1529	0.1417	ABL1/MAP4K4/SLK/MACF1/MMP14/LDB1/PEAK1/DUSP3/BCAS3/SLC9A1/PTK2/SDC4/PPM1F/PHLDB2/TSC1	15
BP	GO:0090109	regulation of cell-substrate junction assembly	15/2159	60/18670	0.002838	0.1529	0.1417	ABL1/MAP4K4/SLK/MACF1/MMP14/LDB1/PEAK1/DUSP3/BCAS3/SLC9A1/PTK2/SDC4/PPM1F/PHLDB2/TSC1	15
BP	GO:0009225	nucleotide-sugar metabolic process	11/2159	38/18670	0.002973	0.1553	0.1439	UAP1/UXS1/GFPT2/SLC35D1/GNE/UAP1L1/FUT8/GNPNAT1/UGDH/EXTL2/PMM1	11
BP	GO:0015804	neutral amino acid transport	11/2159	38/18670	0.002973	0.1553	0.1439	NFKBIE/RGS4/SLC25A38/NFE2L1/CTNS/SLC1A1/SFXN1/SLC1A4/RGS2/SLC38A2/SLC43A2	11
BP	GO:0034101	erythrocyte homeostasis	25/2159	122/18670	0.003045	0.1553	0.1439	ZBTB7A/LDB1/LYAR/SLC25A38/RPS24/HOXA5/NFE2L1/EPAS1/JMJD6/BCL6/ACVR2A/ID2/KMT2E/AMPD3/SFXN1/SH2B3/DNASE2/HMGB2/JAK2/RB1/KLF13/TMOD3/THRA/SLC11A2/CDK6	25
BP	GO:0000725	recombinational repair	27/2159	135/18670	0.003053	0.1553	0.1439	RECQL/NABP1/RFWD3/RAD54L/POLL/RAD50/MCM9/FAN1/RAD51D/RPA2/EXD2/FIGN/RAD54B/NSMCE1/TP53BP1/FEN1/NSMCE2/KLHL15/UBE2N/RAD51C/MCMDC2/TERF2IP/RPA1/HELQ/CDC7/WRN/SWI5	27
BP	GO:0035601	protein deacylation	22/2159	103/18670	0.003089	0.1553	0.1439	SPRED1/SREBF1/SUDS3/LYPLAL1/PRKD1/UCN/BCL6/SPRED2/MIER2/TBL1XR1/C6orf89/CCAR2/MTA3/IFNG/AKAP8/REST/ABHD13/HDAC2/LYPLA2/MSL3/MTA2/BAZ2A	22
BP	GO:0009226	nucleotide-sugar biosynthetic process	8/2159	23/18670	0.003119	0.1553	0.1439	UAP1/UXS1/GFPT2/SLC35D1/UAP1L1/GNPNAT1/UGDH/PMM1	8
BP	GO:0000075	cell cycle checkpoint	39/2159	216/18670	0.003119	0.1553	0.1439	CCND1/DUSP1/CCNB1/CDK5RAP3/NABP1/HINFP/RFWD3/FEM1B/CDKN1B/DOT1L/FBXO6/VPS4A/NSUN2/PCBP4/CNOT6L/RPA2/CNOT6/DONSON/HMGA2/TFDP2/TP53BP1/BABAM1/MUC1/NAE1/CCAR2/GADD45A/BCL2L1/RB1/E2F4/RAD9A/CDC25C/RAD17/CDKN2B/STK33/PCID2/HRAS/TOPBP1/CRY1/USP28	39
BP	GO:0006999	nuclear pore organization	6/2159	14/18670	0.003126	0.1553	0.1439	TMEM170A/AHCTF1/NUP35/SEH1L/NUP98/NUP153	6
BP	GO:0006307	DNA dealkylation involved in DNA repair	5/2159	10/18670	0.003141	0.1553	0.1439	ALKBH3/ALKBH5/ASCC1/FTO/MPG	5
BP	GO:1904526	regulation of microtubule binding	5/2159	10/18670	0.003141	0.1553	0.1439	ABL1/MAPRE1/PPP2CB/HSF1/GAS8	5
BP	GO:0051098	regulation of binding	61/2159	373/18670	0.003262	0.16	0.1483	BMP2/ABL1/LIF/ZBTB7A/JUN/TRIM6/BTBD1/ZFP90/ADNP/ARHGAP28/DDIT3/ITGA2/HES1/ARF6/RIPK2/ZNF593/CAV1/TCF7L2/TNFSF11/DOT1L/NVL/RALB/ID2/HEY2/BTAF1/AKTIP/STPG1/FRMD7/HMGA2/PLAUR/TIAM1/BDNF/ZNF304/MAPRE1/PPP2CB/SNAPIN/DDX11/CSNK1E/HMGB2/GOLGA2/JAK2/GREM2/MARK3/CPNE1/UBASH3B/RB1/IFNG/ID3/HSF1/LARP6/FLOT1/DTNBP1/HOXA3/ZNF462/GAS8/HDAC2/EPHA4/SPTA1/PRKACA/TFIP11/IGF1	61
BP	GO:0042490	mechanoreceptor differentiation	15/2159	61/18670	0.003369	0.1639	0.1519	MKS1/ATP8B1/HES1/FZD2/JAG1/IFT88/SLC4A7/HEY2/SDC4/RBPJ/FAT4/FGFR1/NOTCH1/TRIOBP/SEC24B	15
BP	GO:0009116	nucleoside metabolic process	25/2159	123/18670	0.003411	0.1641	0.1521	HDDC3/MTAP/NT5E/GMPR2/NUDT18/PRPS1/PRPSAP2/CDADC1/IMPDH2/OARD1/ADA/PNP/AMPD3/MFN1/PRPS2/DNPH1/RAB23/RHOQ/UCK1/ACPP/NME5/NME3/NME6/DERA/GNAI3	25
BP	GO:1903391	regulation of adherens junction organization	16/2159	67/18670	0.003438	0.1641	0.1521	ABL1/MAP4K4/SLK/MACF1/MMP14/LDB1/ARF6/PEAK1/DUSP3/BCAS3/SLC9A1/PTK2/SDC4/PPM1F/PHLDB2/TSC1	16
BP	GO:0046128	purine ribonucleoside metabolic process	17/2159	73/18670	0.003455	0.1641	0.1521	HDDC3/MTAP/NT5E/GMPR2/NUDT18/IMPDH2/ADA/PNP/AMPD3/MFN1/RAB23/RHOQ/ACPP/NME5/NME3/NME6/GNAI3	17
BP	GO:0098732	macromolecule deacylation	22/2159	104/18670	0.003499	0.1649	0.1528	SPRED1/SREBF1/SUDS3/LYPLAL1/PRKD1/UCN/BCL6/SPRED2/MIER2/TBL1XR1/C6orf89/CCAR2/MTA3/IFNG/AKAP8/REST/ABHD13/HDAC2/LYPLA2/MSL3/MTA2/BAZ2A	22
BP	GO:0009451	RNA modification	31/2159	163/18670	0.00356	0.1665	0.1542	ELP4/PUS10/TRMT6/RBM15/DIMT1/OSGEPL1/ALKBH3/ALKBH5/JMJD6/SEPHS2/FTO/BCDIN3D/NSUN2/RRNAD1/PARN/TRMT10C/NOP10/HENMT1/LCMT2/NAF1/RPUSD4/TRMT1L/SEPHS1/TRMT2A/OSGEP/QTRT1/TRMT5/ZC3H13/TRMU/DUS1L/ADARB1	31
BP	GO:0006260	DNA replication	47/2159	274/18670	0.00364	0.1689	0.1565	BAZ1A/POLG/DBF4/HMGA1/JUN/RBMS1/RECQL/PRIM1/SLFN11/TOP1/RFWD3/UCN/POLL/SMC3/ORC2/BCL6/RAD50/POLB/PRIMPOL/ING4/MCM9/EREG/RPA2/KCTD13/ORC4/DONSON/POLI/FEN1/NFIC/DDX11/FGFR1/ID3/MCMDC2/DTD1/ZPR1/NUP98/SDE2/RAD9A/ATF1/RPA1/RAD17/CDC7/HRAS/TOPBP1/POLE3/LIG4/WRN	47
BP	GO:0001959	regulation of cytokine-mediated signaling pathway	33/2159	177/18670	0.003732	0.1719	0.1592	BIRC3/SPPL2A/IKBKE/IFNGR2/CBFB/TRIM6/RIPK2/SLIT2/IL1RN/CAV1/OTUD4/IRF3/IFNAR2/F2RL1/LIFR/HIPK1/CASP4/ADAM17/SOCS3/SPHK1/CHUK/TRAF1/SH2B3/JAK2/TNFAIP3/CPNE1/IRGM/IFNG/IRAK2/IL36RN/CD24/PELI3/BIRC2	33
BP	GO:0019827	stem cell population maintenance	30/2159	157/18670	0.003809	0.1728	0.1601	LIF/FOXP1/MED30/LDB1/HES1/LBH/JAG1/TET1/SMC3/ELAVL1/BCL9L/HOOK3/POLR2I/VPS72/RBPJ/EOMES/HMGA2/SRRT/YAP1/EIF4E/TP63/POLR2G/PRDM16/NOTCH1/PBX1/PELO/REST/MED7/ZC3H13/LIG4	30
BP	GO:0031570	DNA integrity checkpoint	30/2159	157/18670	0.003809	0.1728	0.1601	CCND1/CCNB1/CDK5RAP3/HINFP/RFWD3/FEM1B/CDKN1B/DOT1L/FBXO6/PCBP4/CNOT6L/RPA2/CNOT6/DONSON/HMGA2/TFDP2/TP53BP1/BABAM1/MUC1/NAE1/CCAR2/GADD45A/E2F4/RAD9A/CDC25C/RAD17/STK33/TOPBP1/CRY1/USP28	30
BP	GO:1905515	non-motile cilium assembly	14/2159	56/18670	0.003867	0.1741	0.1613	MKS1/IFT172/ARL13B/IFT88/BBS10/INTU/TMEM17/IFT74/BBS2/IFT52/TMEM80/EXOC5/CC2D2A/CEP89	14
BP	GO:0071243	cellular response to arsenic-containing substance	7/2159	19/18670	0.003909	0.1747	0.1618	DDX3X/MKNK2/GSTO1/GSTO2/DAXX/PPIF/HSF1	7
BP	GO:0016241	regulation of macroautophagy	32/2159	171/18670	0.004006	0.1765	0.1635	PRKAB2/ULK1/NUPR1/ATP6V1E2/RIPK2/LRSAM1/PRKAG1/EPM2A/SESN2/MTMR3/IFT88/RALB/SESN3/LAMTOR3/ATG101/LAMTOR4/MLST8/CDK5R1/ATP13A2/IRGM/SPTLC2/PIP4K2A/USP30/ATP6V1B2/SNX5/POLDIP2/PRKACA/RRAGC/GNAI3/PIK3CA/TRIM13/TSC1	32
BP	GO:1904030	negative regulation of cyclin-dependent protein kinase activity	10/2159	34/18670	0.004007	0.1765	0.1635	CDKN1C/HEXIM2/CDKN1B/CDKN2D/NR2F2/CAMK2N1/CDKN2C/TNFAIP3/CEBPA/CDKN2B	10
BP	GO:0032147	activation of protein kinase activity	55/2159	333/18670	0.004075	0.1781	0.165	DUSP6/MAP2K6/BMP2/ABL1/MAP4K4/GHR/DUSP5/SLK/GADD45G/ADNP/ITGB3/ERCC6/RIPK2/ZFP91/FGF1/TNFRSF10A/TAB3/TNFSF11/DAXX/UCN/MAPKAPK5/PRKCZ/MAP3K3/MAP2K1/TNFRSF10B/NEK1/SHC1/DUSP7/MAP4K5/LAMTOR3/TNFSF15/MAP3K5/KIF14/UBE2N/MLST8/PRKAR1A/CDK5R1/RICTOR/PAK2/ECT2/JAK2/GADD45A/GADD45B/TLR4/MAP4K3/IRAK2/STK10/CRKL/AVPI1/DUSP19/PRKAR2A/PRKACA/PIK3CA/IGF1/GPRC5C	55
BP	GO:0033014	tetrapyrrole biosynthetic process	9/2159	29/18670	0.0042	0.1823	0.1689	COX15/SLC25A38/MMAB/NFE2L1/ALAS1/ABCB6/CPOX/SLC11A2/SPTA1	9
BP	GO:0032092	positive regulation of protein binding	20/2159	93/18670	0.004288	0.1835	0.17	BMP2/ABL1/ARF6/RIPK2/CAV1/TCF7L2/NVL/RALB/AKTIP/STPG1/TIAM1/BDNF/MAPRE1/PPP2CB/MARK3/HSF1/FLOT1/HOXA3/EPHA4/SPTA1	20
BP	GO:0006302	double-strand break repair	43/2159	248/18670	0.004304	0.1835	0.17	ZBTB7A/RECQL/PARP2/NABP1/PARP3/RFWD3/RAD54L/PAXIP1/POLL/DCLRE1A/RAD50/POLB/MCM9/FAN1/RAD51D/MLH1/FMN2/RPA2/EXD2/FIGN/HMGA2/RAD54B/NSMCE1/TP53BP1/FEN1/NSMCE2/KLHL15/UBE2N/BABAM1/DDX11/RAD51C/MCMDC2/HSF1/TERF2IP/SETX/RPA1/HELQ/RAD21/CDC7/LIG4/WRN/TFIP11/SWI5	43
BP	GO:1901653	cellular response to peptide	62/2159	385/18670	0.00433	0.1835	0.17	ATP2B1/GHR/SREBF1/ATP6V1E2/CFLAR/ICAM1/RIPK2/GRB10/CAV1/CDK4/GJB2/PDK2/APPL2/NFKB1/RELA/PRKCZ/CASP4/SESN3/SLC9A1/APEX1/C2CD5/GKAP1/PCK2/SHC1/SOCS3/PTK2/FOXC2/PKM/NR4A3/AGTRAP/MYO1C/ENPP1/ERRFI1/PRKCI/PRKAR1A/DDX11/ARID1B/JAK2/SP1/TLR4/AGTR2/ATP6V1B2/RHOQ/HSF1/CCND3/RAB8B/NR4A2/CPEB1/KLF5/MYO5A/IGFBP1/FYN/KLF3/EPHA4/POR/PRKAR2A/PRKACA/PIK3CA/BCL2L2/TSC1/NAMPT/IGF1	62
BP	GO:0000077	DNA damage checkpoint	28/2159	145/18670	0.00435	0.1835	0.17	CCND1/CCNB1/CDK5RAP3/HINFP/RFWD3/FEM1B/CDKN1B/DOT1L/FBXO6/PCBP4/CNOT6L/RPA2/CNOT6/DONSON/HMGA2/TFDP2/TP53BP1/BABAM1/MUC1/CCAR2/GADD45A/E2F4/RAD9A/CDC25C/RAD17/STK33/CRY1/USP28	28
BP	GO:0032392	DNA geometric change	24/2159	119/18670	0.004505	0.1887	0.1748	DDX3X/HMGA1/RECQL/CHD2/ERCC6/CHD1/SMARCA1/RAD54L/RAD50/CHD9/MCM9/RAD54B/GTF2F2/DDX11/HMGB2/POT1/RAD54L2/SETX/RPA1/GTF2H5/HELQ/CHD1L/ERCC6L/WRN	24
BP	GO:0007031	peroxisome organization	18/2159	81/18670	0.004553	0.1895	0.1755	IDH1/PEX11A/CAT/PEX11G/PEX11B/ECH1/NUDT19/PEX12/EHHADH/HMGCL/MPV17/PEX16/RAB8B/PECR/PEX1/ACAA1/ZFAND6/ACOX3	18
BP	GO:0071025	RNA surveillance	6/2159	15/18670	0.004704	0.1944	0.1801	EXOSC8/DXO/PELO/EXOSC4/PCID2/EXOSC10	6
BP	GO:0042542	response to hydrogen peroxide	28/2159	146/18670	0.004803	0.1971	0.1826	FOSL1/ABL1/DUSP1/JUN/CAT/KPNA4/AQP1/RELA/PPIF/APEX1/ADA/SPHK1/TXNIP/MAP3K5/NR4A3/OSER1/PPP2CB/ECT2/TNFAIP3/TRPA1/PDGFRB/IMPACT/HSF1/GLRX2/SETX/FYN/HDAC2/ZNF580	28
BP	GO:0007224	smoothened signaling pathway	26/2159	133/18670	0.004949	0.1999	0.1852	MKS1/IFT172/HES1/B9D1/ARL13B/HIPK1/NKX2-2/BOC/FGFR2/ENPP1/IFT46/INTU/TMEM17/ARL6/RB1/MGRN1/IFT52/ROR2/DCDC2/HHAT/TMEM231/GAS8/FOXF1/POR/CC2D2A/PRKACA	26
BP	GO:0071383	cellular response to steroid hormone stimulus	43/2159	250/18670	0.004987	0.1999	0.1852	ABHD2/ATP2B1/CBFB/ZBTB7A/FOXP1/CFLAR/ICAM1/PGRMC2/NR1D2/LBH/UFSP2/GJB2/AQP1/DAXX/NR2F2/PCK2/TGFB1I1/NR4A3/CASP9/ERRFI1/YAP1/JAK2/TRIM68/EIF4E/NR3C1/TP63/RB1/NR2F1/FBXO32/AGTR2/THRA/NR4A2/GPAM/SMARCA4/REST/STRN3/SMYD3/VDR/NR2C2/PGR/NR3C2/DDX5/CRY1	43
BP	GO:1904031	positive regulation of cyclin-dependent protein kinase activity	10/2159	35/18670	0.005038	0.1999	0.1852	CCND1/CCNB1/CCNYL1/CDKN1B/ADAM17/CDK5R1/CKS2/CKS1B/CCND3/CCNT1	10
BP	GO:0060562	epithelial tube morphogenesis	53/2159	322/18670	0.005089	0.1999	0.1852	SIX1/BMP2/MKS1/ABL1/SPRY2/RBM15/MMP14/HOXA11/FOXP1/IFT172/HES1/FZD2/LIAS/SLIT2/FGF1/EPHA2/LMO4/RDH10/HOXA5/ARL13B/ETV5/SOX8/DEAF1/DVL3/FZD1/DVL2/SDC4/PGF/RBPJ/KLHL3/FGFR2/PHACTR4/LUZP1/FOXC2/FAT4/YAP1/CCM2/VASP/NOTCH1/AGTR2/IFT52/PBX1/APAF1/SEC24B/FOXF1/VDR/TBX2/MAGED1/EPHA4/CC2D2A/PGR/PRKACA/TSC1	53
BP	GO:0032259	methylation	59/2159	366/18670	0.005168	0.1999	0.1852	FOS/TPMT/TRMT6/RBM15/PCMT1/COMTD1/DIMT1/PRDM10/RNF20/ATF7IP/DPH5/DNMT1/COQ5/GSTO1/TET1/PAXIP1/DNMT3A/SETD1B/DOT1L/METTL7B/PRMT9/SETD4/PCMTD2/AS3MT/METTL17/HEMK1/KMT2E/BCDIN3D/NSUN2/RRNAD1/BEND3/SETDB1/PHF1/METTL18/ZNF304/TDRD1/ASH2L/KDM1B/TRMT10C/SNW1/GSPT1/PRDM16/HENMT1/COQ3/PAXBP1/LCMT2/DMAP1/FAM98B/WDR5B/SUV39H2/SMYD3/TRMT1L/SETD3/TRMT2A/TRMT5/PIK3CA/ZC3H13/MTA2/BAZ2A	59
BP	GO:0000185	activation of MAPKKK activity	5/2159	11/18670	0.005213	0.1999	0.1852	GADD45G/MAP4K5/GADD45A/GADD45B/MAP4K3	5
BP	GO:0019852	L-ascorbic acid metabolic process	5/2159	11/18670	0.005213	0.1999	0.1852	GSTO1/GSTO2/SLC2A3/AKR1A1/SLC23A2	5
BP	GO:0032611	interleukin-1 beta production	21/2159	101/18670	0.005266	0.1999	0.1852	S1PR3/EGR1/FOXP1/RIPK2/ARG2/HK1/F2RL1/PANX1/SERPINB1/SPHK1/ERRFI1/AIM2/JAK2/TNFAIP3/TLR4/IFNG/CPTP/HSPB1/MR1/TRIM16/IGF1	21
BP	GO:0046580	negative regulation of Ras protein signal transduction	13/2159	52/18670	0.005279	0.1999	0.1852	SPRY2/RASA2/SPRY4/CCDC125/BCL6/KCTD13/CUL3/PPP2CB/STMN3/EPHB2/STAMBP/RASA1/KCTD10	13
BP	GO:1901657	glycosyl compound metabolic process	28/2159	147/18670	0.005294	0.1999	0.1852	HDDC3/MTAP/NT5E/GMPR2/NUDT18/PRPS1/PRPSAP2/CDADC1/IMPDH2/OARD1/ADA/PNP/AMPD3/MFN1/AKR1A1/ABHD10/PRPS2/DNPH1/RAB23/RHOQ/UCK1/LCMT2/ACPP/NME5/NME3/NME6/DERA/GNAI3	28
BP	GO:0030218	erythrocyte differentiation	23/2159	114/18670	0.005324	0.1999	0.1852	ZBTB7A/LDB1/LYAR/SLC25A38/HOXA5/NFE2L1/EPAS1/JMJD6/BCL6/ACVR2A/ID2/KMT2E/SFXN1/SH2B3/DNASE2/HMGB2/JAK2/RB1/KLF13/TMOD3/THRA/SLC11A2/CDK6	23
BP	GO:0071480	cellular response to gamma radiation	9/2159	30/18670	0.005395	0.1999	0.1852	EGR1/ELK1/YAP1/BCL2L1/HSF1/GTF2H5/HRAS/POLE3/WRN	9
BP	GO:1902751	positive regulation of cell cycle G2/M phase transition	9/2159	30/18670	0.005395	0.1999	0.1852	CCND1/CCNB1/CDK4/RAB11A/MTA3/RAD51C/PBX1/CDC25C/CDC7	9
BP	GO:0051058	negative regulation of small GTPase mediated signal transduction	14/2159	58/18670	0.005422	0.1999	0.1852	SPRY2/RASA2/SPRY4/CCDC125/SLIT2/BCL6/KCTD13/CUL3/PPP2CB/STMN3/EPHB2/STAMBP/RASA1/KCTD10	14
BP	GO:0071385	cellular response to glucocorticoid stimulus	14/2159	58/18670	0.005422	0.1999	0.1852	ATP2B1/CFLAR/ICAM1/GJB2/AQP1/PCK2/CASP9/ERRFI1/EIF4E/NR3C1/FBXO32/AGTR2/REST/SMYD3	14
BP	GO:0008154	actin polymerization or depolymerization	37/2159	209/18670	0.005456	0.1999	0.1852	VILL/MSRB2/ARHGAP28/ICAM1/DIAPH1/ARF6/SLIT2/TMOD2/CXCL12/JMY/F2RL1/RHOBTB1/ARPC5L/ARPC5/GMFB/FMN2/PFN4/EVL/ARPC2/MYO1C/FCHSD2/RICTOR/JAK2/PFN2/ARPC4/VASP/TMOD3/TRIOBP/MSRB1/ENAH/PREX1/WDR1/CAP2/WASL/RASA1/CDC42EP2/SPTA1	37
BP	GO:0010257	NADH dehydrogenase complex assembly	15/2159	64/18670	0.005468	0.1999	0.1852	NDUFV2/TIMMDC1/NDUFA6/OXA1L/NDUFB5/BCS1L/FOXRED1/NDUFAF3/NDUFAF4/TMEM126B/NDUFS3/NDUFV1/NDUFS2/NDUFB10/NDUFA11	15
BP	GO:0032981	mitochondrial respiratory chain complex I assembly	15/2159	64/18670	0.005468	0.1999	0.1852	NDUFV2/TIMMDC1/NDUFA6/OXA1L/NDUFB5/BCS1L/FOXRED1/NDUFAF3/NDUFAF4/TMEM126B/NDUFS3/NDUFV1/NDUFS2/NDUFB10/NDUFA11	15
BP	GO:0060119	inner ear receptor cell development	11/2159	41/18670	0.005641	0.2042	0.1892	MKS1/ATP8B1/HES1/FZD2/IFT88/SLC4A7/SDC4/FAT4/FGFR1/TRIOBP/SEC24B	11
BP	GO:0018205	peptidyl-lysine modification	63/2159	397/18670	0.005652	0.2042	0.1892	BAZ1A/HINT2/LOXL1/LIF/EGR1/LDB1/TAF5L/JADE1/LOXL4/EGR2/KANSL1L/DNMT1/PAXIP1/VIPAS39/MRGBP/SETD1B/JMJD6/DOT1L/CPA4/RAE1/RELA/PHF20/SETD4/MSL1/ING4/KMT2E/STX1A/JADE3/BEND3/SENP5/DPF2/KAT6A/SETDB1/PHF1/NSMCE2/ZNF304/TAF6L/KANSL1/MUC1/ASH2L/NUP35/SNW1/TADA2A/PRDM16/TAF12/UBA2/SEH1L/SAE1/DMAP1/NUP98/WDR5B/SUV39H2/SMYD3/NUP153/SETD3/HDAC2/TRIM16/POR/TAF5/HAT1/SUPT7L/MSL3/POLE3	63
BP	GO:0120163	negative regulation of cold-induced thermogenesis	12/2159	47/18670	0.006039	0.2151	0.1993	MAP2K6/DDIT3/TLE3/DOCK7/ADAM17/RBPJ/ACOT13/FOXC2/RB1/TLR4/NOTCH1/HOXC10	12
BP	GO:1901068	guanosine-containing compound metabolic process	12/2159	47/18670	0.006039	0.2151	0.1993	HDDC3/GMPR2/NUDT18/IMPDH2/AMPD3/MFN1/RAB23/RHOQ/NME5/NME3/NME6/GNAI3	12
BP	GO:0032543	mitochondrial translation	26/2159	135/18670	0.006061	0.2151	0.1993	MRPL40/RMND1/NOA1/DARS2/MRPS6/OXA1L/MTIF2/UQCC1/MRPS18C/MRPL17/MRPS14/TRMT10C/MRPS18A/NGRN/MTRF1L/MRPL11/MRPL10/MRPS16/RPUSD4/MRPL24/MRPS33/MRPS31/LARS2/MRRF/MRPS36/MRPL2	26
BP	GO:0008654	phospholipid biosynthetic process	44/2159	260/18670	0.006125	0.2154	0.1995	SAMD8/ETNK1/LPCAT1/IDH1/MPPE1/SYNJ2/PIGC/PGAP2/MTMR12/DDHD1/PTPMT1/SERAC1/PLEKHA3/MTMR3/MFSD2A/SH3YL1/MVK/MTMR9/LCLAT1/IMPA1/GPD1L/AJUBA/ACP6/CPNE1/SBF1/INPP5F/SPTLC2/PIP4K2A/PIGB/PIGV/NUS1/PIK3CD/GPAM/PIK3C2B/PLA2G12A/MTMR7/LPCAT4/PGAP3/CDIPT/PIP5K1A/ABHD3/MVD/RUFY1/PIK3CA	44
BP	GO:0018394	peptidyl-lysine acetylation	31/2159	169/18670	0.006172	0.2154	0.1995	BAZ1A/HINT2/LIF/LDB1/TAF5L/JADE1/KANSL1L/PAXIP1/MRGBP/CPA4/PHF20/MSL1/ING4/JADE3/BEND3/DPF2/KAT6A/TAF6L/KANSL1/MUC1/TADA2A/TAF12/DMAP1/HDAC2/TRIM16/POR/TAF5/HAT1/SUPT7L/MSL3/POLE3	31
BP	GO:2001233	regulation of apoptotic signaling pathway	64/2159	406/18670	0.006176	0.2154	0.1995	BDKRB2/DDX3X/NUPR1/G0S2/CFLAR/DDIT3/ICAM1/MCL1/CAV1/TNFRSF10A/PLEKHF1/CXCL12/ACKR3/BCL2A1/BID/FEM1B/TCF7L2/PTPMT1/PMAIP1/RELA/PPIF/CDKN2D/TNFRSF10B/ITPRIP/PDCD5/TRAF1/PLAUR/TFDP2/BDNF/TNFSF10/CD44/CAAP1/RRN3/TNFRSF12A/YAP1/PAK2/HMGB2/JAK2/MUC1/CCAR2/TNFAIP3/BCL2L1/FGFR1/TP63/RB1/HSPB1/AGTR2/NDUFS3/NR4A2/APAF1/RAD9A/STYXL1/EYA4/NME5/FYN/DEPTOR/PPP3CC/HNRNPK/PELI3/MAGED1/MLLT11/GNAI3/BCL2L2/IGF1	64
BP	GO:0060563	neuroepithelial cell differentiation	13/2159	53/18670	0.00627	0.2166	0.2007	BMP2/ABL1/HES1/JAG1/B9D1/SLC4A7/HEY2/RBPJ/FGFR1/NOTCH1/TRIOBP/TMEM231/SEC24B	13
BP	GO:0042795	snRNA transcription by RNA polymerase II	16/2159	71/18670	0.006283	0.2166	0.2007	ZNF143/ZC3H8/NABP1/POLR2I/INTS2/GTF2F2/SRRT/POU2F2/SP1/ELL/POLR2G/POU2F1/RPRD1A/TAF5/CCNT1/ICE2	16
BP	GO:0060759	regulation of response to cytokine stimulus	34/2159	190/18670	0.006344	0.2175	0.2015	BIRC3/SPPL2A/IKBKE/IFNGR2/CBFB/TRIM6/RIPK2/SLIT2/IL1RN/CAV1/OTUD4/IRF3/IFNAR2/F2RL1/LIFR/HIPK1/CASP4/ADAM17/SOCS3/SPHK1/CHUK/TRAF1/SH2B3/JAK2/TNFAIP3/CPNE1/IRGM/TLR4/IFNG/IRAK2/IL36RN/CD24/PELI3/BIRC2	34
BP	GO:0031058	positive regulation of histone modification	19/2159	90/18670	0.006513	0.2193	0.2032	SREBF1/LIF/CCNB1/RNF20/DNMT1/TET1/PAXIP1/PRKD1/BCL6/KMT2E/C6orf89/PHF1/UBE2N/ZNF304/MUC1/SNW1/TADA2A/AKAP8/PAXBP1	19
BP	GO:0032651	regulation of interleukin-1 beta production	19/2159	90/18670	0.006513	0.2193	0.2032	S1PR3/EGR1/FOXP1/RIPK2/ARG2/HK1/PANX1/SERPINB1/SPHK1/ERRFI1/AIM2/JAK2/TNFAIP3/TLR4/IFNG/CPTP/HSPB1/TRIM16/IGF1	19
BP	GO:0051091	positive regulation of DNA-binding transcription factor activity	44/2159	261/18670	0.006564	0.2193	0.2032	FOSL1/ZBTB7A/CFLAR/DDIT3/NFKB2/ICAM1/FZD2/RIPK2/CAT/CAV1/TAB3/NDP/JMY/PRKD1/NFKB1/TNFSF11/RELA/PRKCZ/RHEBL1/NKX2-2/FZD1/SPHK1/DVL2/CHUK/TRAF1/TP53BP1/IRAK4/UBE2N/PRKCI/AIM2/JAK2/MID2/TLR4/IRAK2/TAF12/MTDH/TERF2IP/SMARCA4/FLOT1/PPRC1/NHLH2/LRRFIP1/DHX33/TRIM13	44
BP	GO:0006661	phosphatidylinositol biosynthetic process	23/2159	116/18670	0.006623	0.2193	0.2032	MPPE1/SYNJ2/PIGC/PGAP2/MTMR12/PLEKHA3/MTMR3/SH3YL1/MTMR9/IMPA1/SBF1/INPP5F/PIP4K2A/PIGB/PIGV/PIK3CD/PIK3C2B/MTMR7/PGAP3/CDIPT/PIP5K1A/RUFY1/PIK3CA	23
BP	GO:0007033	vacuole organization	30/2159	163/18670	0.006646	0.2193	0.2032	ULK1/NUPR1/LRSAM1/HOOK2/NDP/TMEM175/MTMR3/IFT88/RALB/HOOK3/VPS11/VPS4A/AKTIP/ATG101/GABARAPL1/HPS4/ZKSCAN3/SNAPIN/CCDC115/ATP13A2/IRGM/PIP4K2A/RAB23/GABARAP/PIK3C2B/TMEM41B/MAN2A1/LAPTM4B/CLN3/ACP2	30
BP	GO:1905269	positive regulation of chromatin organization	21/2159	103/18670	0.006652	0.2193	0.2032	SREBF1/LIF/CCNB1/RNF20/ATF7IP/DNMT1/TET1/PAXIP1/PRKD1/BCL6/KMT2E/C6orf89/SETDB1/PHF1/UBE2N/ZNF304/MUC1/SNW1/TADA2A/AKAP8/PAXBP1	21
BP	GO:0044282	small molecule catabolic process	69/2159	445/18670	0.006778	0.2193	0.2032	ABHD2/HDDC3/GPD2/SDSL/NT5E/NUDT18/GCDH/ETFB/SCARF1/RBKS/ADO/MCCC1/ECI1/SYNJ2/IVD/ARG2/ALDH5A1/BCKDHB/HK1/ACACB/GSTZ1/FUT4/ALDH7A1/CDADC1/ECH1/DCXR/NUDT19/ENOSF1/SESN2/PCCB/ABAT/SLC9A1/FOXK2/BCAT2/ADA/PCK2/HYKK/EHHADH/GALM/PNP/IMPA1/MPST/FUT8/AKR1A1/PKM/ABHD10/BLMH/HMGCL/ADPGK/CD44/SNX17/MCEE/PFKP/DBT/ALDH6A1/INPP5B/PECR/SLC25A17/QDPR/HK2/MTMR7/PFKM/ACAA1/ABHD3/DERA/ACOX3/HOGA1/PCYOX1L/THNSL2	69
BP	GO:0010566	regulation of ketone biosynthetic process	6/2159	16/18670	0.006799	0.2193	0.2032	BMP2/EGR1/CLCN2/COQ3/PPTC7/REST	6
BP	GO:0035372	protein localization to microtubule	6/2159	16/18670	0.006799	0.2193	0.2032	DIAPH1/MAPRE1/MID2/MID1/CRIPT/MAP1A	6
BP	GO:0043981	histone H4-K5 acetylation	6/2159	16/18670	0.006799	0.2193	0.2032	JADE1/KANSL1L/PHF20/ING4/JADE3/KANSL1	6
BP	GO:0043982	histone H4-K8 acetylation	6/2159	16/18670	0.006799	0.2193	0.2032	JADE1/KANSL1L/PHF20/ING4/JADE3/KANSL1	6
BP	GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II	9/2159	31/18670	0.006836	0.2194	0.2032	FOS/BMP2/SREBF1/JUN/RELA/NR3C1/KLF5/SMARCA4/TEAD1	9
BP	GO:0007044	cell-substrate junction assembly	20/2159	97/18670	0.007009	0.2208	0.2046	ABL1/MAP4K4/SLK/MACF1/MMP14/LDB1/ITGA2/PEAK1/DUSP3/BCAS3/SLC9A1/PTK2/SDC4/AJUBA/TRIP6/PLEC/PPM1F/PIP5K1A/PHLDB2/TSC1	20
BP	GO:0060996	dendritic spine development	20/2159	97/18670	0.007009	0.2208	0.2046	EPHB3/ARF6/DOCK10/CTNND2/SIPA1L1/TIAM1/CDK5R1/PAK2/ARID1B/ASAP1/SRGAP2C/DLG4/DNM3/EPHB2/CAPRIN1/WASL/HDAC2/PDLIM5/EPHA4/ACSL4	20
BP	GO:0016331	morphogenesis of embryonic epithelium	28/2159	150/18670	0.007027	0.2208	0.2046	SIX1/MKS1/ABL1/TBX18/IFT172/FZD2/LIAS/LMO4/RDH10/SOX8/DEAF1/DVL3/FZD1/DVL2/SDC4/TGFB1I1/FGFR2/PHACTR4/LUZP1/TP63/VASP/IFT52/APAF1/SEC24B/CC2D2A/PRKACA/VEGFC/TSC1	28
BP	GO:0043407	negative regulation of MAP kinase activity	17/2159	78/18670	0.007028	0.2208	0.2046	DUSP6/HIPK3/SPRY2/DUSP1/SPRED1/DUSP5/SPRY4/CDK5RAP3/RGS4/CAV1/LAX1/DUSP3/SPRED2/DUSP7/SH2B3/RGS2/DUSP19	17
BP	GO:0043543	protein acylation	42/2159	248/18670	0.007183	0.2211	0.2049	BAZ1A/FAM161A/HINT2/LIF/NUPR1/LDB1/TAF5L/JADE1/KANSL1L/PAXIP1/MRGBP/CPA4/PHF20/MSL1/ING4/JADE3/NAA20/PPM1B/EHHADH/SPHK1/BEND3/DPF2/KAT6A/ZDHHC4/TAF6L/KANSL1/MUC1/TADA2A/TAF12/NATD1/TERF2IP/HHAT/DMAP1/HDAC2/TRIM16/POR/TAF5/ZDHHC5/HAT1/SUPT7L/MSL3/POLE3	42
BP	GO:0009301	snRNA transcription	16/2159	72/18670	0.007232	0.2211	0.2049	ZNF143/ZC3H8/NABP1/POLR2I/INTS2/GTF2F2/SRRT/POU2F2/SP1/ELL/POLR2G/POU2F1/RPRD1A/TAF5/CCNT1/ICE2	16
BP	GO:0006779	porphyrin-containing compound biosynthetic process	8/2159	26/18670	0.007248	0.2211	0.2049	COX15/SLC25A38/NFE2L1/ALAS1/ABCB6/CPOX/SLC11A2/SPTA1	8
BP	GO:0034329	cell junction assembly	41/2159	241/18670	0.007251	0.2211	0.2049	ABL1/MAP4K4/SLK/CBFB/MACF1/MMP14/LDB1/ITGA2/PEAK1/CAV1/EPHA2/GJB2/DUSP3/TJP1/HIPK1/PARD3/BCAS3/MPP7/SLC9A1/CTNND2/FLNC/PTK2/SDC4/AJUBA/LIMS2/TRIP6/MYO1C/PRKCI/PLEC/ECT2/VASP/SMAD7/MTDH/RHOC/WDR1/FLOT1/PPM1F/PIP5K1A/PRKACA/PHLDB2/TSC1	41
BP	GO:0009081	branched-chain amino acid metabolic process	7/2159	21/18670	0.007331	0.2211	0.2049	MCCC1/IVD/BCKDHB/BCAT2/HMGCL/DBT/ALDH6A1	7
BP	GO:0009083	branched-chain amino acid catabolic process	7/2159	21/18670	0.007331	0.2211	0.2049	MCCC1/IVD/BCKDHB/BCAT2/HMGCL/DBT/ALDH6A1	7
BP	GO:0055093	response to hyperoxia	7/2159	21/18670	0.007331	0.2211	0.2049	POLG/CAT/CAV1/CDK4/POLB/PDGFRB/HDAC2	7
BP	GO:1901992	positive regulation of mitotic cell cycle phase transition	19/2159	91/18670	0.007361	0.2211	0.2049	DDX3X/CCND1/CCNB1/CDK4/ADAM17/KMT2E/APEX1/PLCB1/RAB11A/NSMCE2/CUL3/MTA3/RAD51C/RB1/TMOD3/CCND3/PBX1/CDC25C/CDC7	19
BP	GO:0035384	thioester biosynthetic process	13/2159	54/18670	0.007404	0.2211	0.2049	GCDH/PDP2/ACACB/GSTZ1/PDK2/ELOVL7/HSD17B8/ELOVL6/DLAT/ELOVL4/PDP1/ACSL4/PPCS	13
BP	GO:0071616	acyl-CoA biosynthetic process	13/2159	54/18670	0.007404	0.2211	0.2049	GCDH/PDP2/ACACB/GSTZ1/PDK2/ELOVL7/HSD17B8/ELOVL6/DLAT/ELOVL4/PDP1/ACSL4/PPCS	13
BP	GO:2000142	regulation of DNA-templated transcription, initiation	10/2159	37/18670	0.007716	0.2293	0.2124	FOSL1/JUN/SUB1/ATF7IP/PAXIP1/PSMC2/HEY2/RRN3/THRA/SETX	10
BP	GO:0051260	protein homooligomerization	56/2159	351/18670	0.007798	0.2303	0.2133	IKBKE/LNX2/ZBTB1/EHD1/CAT/CAV1/ALDH5A1/ACACB/TOR1A/BID/PEX11B/APPL2/GCH1/DCXR/JMJD6/TNFSF11/KCTD18/IMPDH2/ANGPTL4/ELAVL1/DPYSL3/LY6G5C/SLC1A1/KCND1/BEND3/CBY1/TMEM38A/PCBD2/KCTD13/ACOT13/PKM/KCTD5/EVL/CEP57/TP53BP1/PRTG/PFKP/GOLGA2/ECT2/TP63/TRPA1/VASP/HSF1/RHOC/APAF1/FLOT1/ACPP/KCTD9/PFKM/SLC6A1/MICU1/MIEF2/KCTD10/TOR1B/CALHM1/EMILIN1	56
BP	GO:0032984	protein-containing complex disassembly	53/2159	329/18670	0.007824	0.2303	0.2133	MRPL40/HMGA1/VILL/MAP1S/CHMP7/FZD2/NFE2/CAV1/TMOD2/F2RL1/MRPS6/OXA1L/DVL3/VPS4A/MTIF2/FZD1/DVL2/GABARAPL1/MRPS18C/C12orf65/MRPL17/MRPS14/SNAPIN/KIF5B/SCAF8/IRGM/MRPS18A/GSPT1/STMN3/MID1/MTRF1L/TMOD3/MAP1A/GABARAP/TRIOBP/MRPL11/PELO/TECPR1/SMARCA4/MRPL10/WDR1/SETX/MRPS16/MRPL24/MRPS33/MRPS31/CLN3/SPTA1/MRRF/KIF2B/MRPS36/MRPL2/TFIP11	53
BP	GO:0051099	positive regulation of binding	32/2159	179/18670	0.008034	0.233	0.2159	BMP2/ABL1/TRIM6/ITGA2/HES1/ARF6/RIPK2/CAV1/TCF7L2/NVL/RALB/AKTIP/STPG1/HMGA2/PLAUR/TIAM1/BDNF/MAPRE1/PPP2CB/DDX11/HMGB2/JAK2/MARK3/RB1/IFNG/HSF1/LARP6/FLOT1/HOXA3/EPHA4/SPTA1/IGF1	32
BP	GO:0006733	oxidoreduction coenzyme metabolic process	36/2159	207/18670	0.00805	0.233	0.2159	GPD2/ZBTB7A/NT5E/NUPR1/IDH1/RBKS/COQ5/HK1/PRKAG1/DCXR/RAE1/RPIA/FOXK2/GPD1L/PKM/ADPGK/PARP16/COQ7/PFKP/NUP35/IFNG/RNLS/SEH1L/COQ3/PPTC7/FMO2/NUP98/MDH1B/HK2/NUP153/PFKM/NUDT17/DERA/PGLS/NAMPT/IGF1	36
BP	GO:0006020	inositol metabolic process	5/2159	12/18670	0.008093	0.233	0.2159	SLC5A3/PPIP5K1/IMPA1/PPIP5K2/IMPAD1	5
BP	GO:0090161	Golgi ribbon formation	5/2159	12/18670	0.008093	0.233	0.2159	STX6/TMED5/GOLGA2/GOLPH3/VAMP4	5
BP	GO:0061008	hepaticobiliary system development	26/2159	138/18670	0.00811	0.233	0.2159	MKS1/CCND1/JUN/CFLAR/ITGA2/HES1/ARF6/PTCD2/DBP/RELA/ADA/PCK2/MPST/GNPNAT1/LIMS2/PKM/HMGCL/CUL3/UPF2/AACS/TNFAIP3/CEBPA/NOTCH1/QDPR/MAN2A1/PIK3CA	26
BP	GO:0045687	positive regulation of glial cell differentiation	11/2159	43/18670	0.008275	0.2336	0.2164	TNFRSF1B/BMP2/LIF/HES1/CLCF1/RELA/ID2/NKX2-2/ZNF488/NOTCH1/HDAC2	11
BP	GO:0060612	adipose tissue development	11/2159	43/18670	0.008275	0.2336	0.2164	CDK4/PAXIP1/SOX8/ID2/FTO/TBL1XR1/AACS/SPTLC2/SLC25A25/SH3PXD2B/PIK3CA	11
BP	GO:0032496	response to lipopolysaccharide	53/2159	330/18670	0.008301	0.2336	0.2164	BDKRB1/FOS/TNFRSF1B/PTGER2/ABL1/LOXL1/JUN/TRIM6/CD274/FOXP1/NFKBIL1/NFKB2/ICAM1/RIPK2/LIAS/IL1RN/PTGFR/CDK4/IRF3/TRIB1/GJB2/PELI1/IFNAR1/NFKB1/GCH1/RELA/THBD/RPS6KA3/ADAM17/PDE4D/CHUK/FGFR2/CASP9/HMGB2/JAK2/TNFAIP3/IRGM/PDCD1LG2/TLR4/IRAK2/IL36RN/NOTCH1/HSF1/MTDH/AKAP8/NFKBIB/JUNB/IL12A/HDAC2/ANKRD1/GJB6/IL36B/MGST2	53
BP	GO:0006637	acyl-CoA metabolic process	21/2159	105/18670	0.008323	0.2336	0.2164	GCDH/ACOT7/FAR2/PDP2/ACACB/GSTZ1/PDK2/ELOVL7/MVK/HSD17B8/ELOVL6/ACOT13/ACBD6/HMGCL/MCEE/DLAT/ELOVL4/MVD/PDP1/ACSL4/PPCS	21
BP	GO:0035383	thioester metabolic process	21/2159	105/18670	0.008323	0.2336	0.2164	GCDH/ACOT7/FAR2/PDP2/ACACB/GSTZ1/PDK2/ELOVL7/MVK/HSD17B8/ELOVL6/ACOT13/ACBD6/HMGCL/MCEE/DLAT/ELOVL4/MVD/PDP1/ACSL4/PPCS	21
BP	GO:0042491	inner ear auditory receptor cell differentiation	9/2159	32/18670	0.008554	0.2342	0.217	HES1/JAG1/SLC4A7/HEY2/RBPJ/FGFR1/NOTCH1/TRIOBP/SEC24B	9
BP	GO:0046039	GTP metabolic process	9/2159	32/18670	0.008554	0.2342	0.217	IMPDH2/AMPD3/MFN1/RAB23/RHOQ/NME5/NME3/NME6/GNAI3	9
BP	GO:0046685	response to arsenic-containing substance	9/2159	32/18670	0.008554	0.2342	0.217	DDX3X/MKNK2/GSTO1/GSTO2/DAXX/PPIF/SRRT/CPOX/HSF1	9
BP	GO:0060674	placenta blood vessel development	9/2159	32/18670	0.008554	0.2342	0.217	FOSL1/RBM15/HES1/NR2F2/MAP2K1/HEY2/SOCS3/RBPJ/JUNB	9
BP	GO:0006475	internal protein amino acid acetylation	30/2159	166/18670	0.008621	0.2342	0.217	BAZ1A/LIF/LDB1/TAF5L/JADE1/KANSL1L/PAXIP1/MRGBP/CPA4/PHF20/MSL1/ING4/JADE3/EHHADH/BEND3/DPF2/KAT6A/TAF6L/KANSL1/MUC1/TADA2A/TAF12/DMAP1/TRIM16/POR/TAF5/HAT1/SUPT7L/MSL3/POLE3	30
BP	GO:0042733	embryonic digit morphogenesis	14/2159	61/18670	0.008658	0.2342	0.217	MKS1/OSR2/HOXA11/B9D1/INTU/IMPAD1/NOTCH1/IFT52/ECE1/ROR2/GNA12/TMEM231/HDAC2/TBX2	14
BP	GO:0071384	cellular response to corticosteroid stimulus	14/2159	61/18670	0.008658	0.2342	0.217	ATP2B1/CFLAR/ICAM1/GJB2/AQP1/PCK2/CASP9/ERRFI1/EIF4E/NR3C1/FBXO32/AGTR2/REST/SMYD3	14
BP	GO:0002011	morphogenesis of an epithelial sheet	13/2159	55/18670	0.008693	0.2342	0.217	JAG1/TOR1A/LIN7C/ADAM17/HBEGF/DVL2/AJUBA/PHACTR4/CD44/PDPN/NOTCH1/RHOC/PHLDB2	13
BP	GO:1903510	mucopolysaccharide metabolic process	22/2159	112/18670	0.008715	0.2342	0.217	ABCC5/CHST7/ST3GAL2/B4GALT3/GLCE/CHST2/SLC35D1/CHST14/ST3GAL1/B3GNT2/NFKB1/B4GALT5/SLC9A1/UGDH/CD44/B4GALT6/HAS1/CSGALNACT2/IMPAD1/CHST15/OMD/CHST12	22
BP	GO:1905475	regulation of protein localization to membrane	33/2159	187/18670	0.008734	0.2342	0.217	MMP14/ARF6/EPHA2/RAB11FIP2/BID/PMAIP1/PRKCZ/C2CD5/VPS4A/RHOG/STAC/RAB11A/PDCD5/TFDP2/MYO1C/GDI1/PRKCI/CDK5R1/KIF5B/BCL2L1/TP63/IFNG/NKD2/CRIPT/AP2M1/RHOQ/EPHB2/PICALM/FYN/PPP3CC/CRKL/MIEF2/HRAS	33
BP	GO:0030522	intracellular receptor signaling pathway	46/2159	280/18670	0.00889	0.2373	0.2199	BIRC3/MAP2K6/NLRX1/CBFB/SREBF1/ZBTB7A/FOXP1/DCBLD2/RIPK2/NR1D2/LBH/UFSP2/IRF3/TAB3/DAXX/RELA/NR2F2/TGFB1I1/NR4A3/UBE2N/YAP1/JAK2/TRIM68/TNFAIP3/IRGM/NR3C1/SNW1/TP63/RB1/TLR4/NR2F1/IRAK2/DHRS3/THRA/NR4A2/GPAM/SMARCA4/STRN3/CRKL/VDR/BIRC2/TRIM16/PGR/CREM/DDX5/CRY1	46
BP	GO:2001234	negative regulation of apoptotic signaling pathway	39/2159	230/18670	0.009133	0.2396	0.222	BDKRB2/DDX3X/CFLAR/ICAM1/MCL1/TNFRSF10A/CXCL12/ACKR3/BCL2A1/BID/TCF7L2/RELA/PPIF/CDKN2D/TNFRSF10B/ITPRIP/PLAUR/BDNF/TNFSF10/CD44/CAAP1/RRN3/YAP1/HMGB2/MUC1/CCAR2/TNFAIP3/BCL2L1/RB1/HSPB1/NDUFS3/NR4A2/EYA4/NME5/FYN/PELI3/GNAI3/BCL2L2/IGF1	39
BP	GO:0044839	cell cycle G2/M phase transition	44/2159	266/18670	0.009175	0.2396	0.222	CCND1/PPP2R2A/PHLDA1/CCNB1/CDK5RAP3/CDK4/PSME4/PAXIP1/PSMC2/VPS4A/PLCB1/ODF2/RAB11A/TUBB4B/HAUS5/KIF14/AJUBA/DONSON/HMGA2/CEP70/CEP57/PPME1/BABAM1/MAPRE1/HAUS6/PSMD4/CSNK1E/NAE1/FBXL15/MTA3/RAD51C/ATF5/AKAP8/PBX1/TUBA4A/CDC25C/RAD21/RAD17/CDKN2B/CDC7/PRKACA/TOPBP1/SDCCAG8/HAUS3	44
BP	GO:0043921	modulation by host of viral transcription	8/2159	27/18670	0.009276	0.2396	0.222	JUN/CHD1/HMGA2/SP1/SNW1/SMARCA4/REST/CCNT1	8
BP	GO:0046885	regulation of hormone biosynthetic process	8/2159	27/18670	0.009276	0.2396	0.222	BMP2/EGR1/NFKB1/IFNG/CLCN2/REST/VDR/POR	8
BP	GO:0052472	modulation by host of symbiont transcription	8/2159	27/18670	0.009276	0.2396	0.222	JUN/CHD1/HMGA2/SP1/SNW1/SMARCA4/REST/CCNT1	8
BP	GO:0044774	mitotic DNA integrity checkpoint	21/2159	106/18670	0.009278	0.2396	0.222	CCND1/CCNB1/CDK5RAP3/RFWD3/CDKN1B/PCBP4/CNOT6L/RPA2/CNOT6/DONSON/HMGA2/TFDP2/MUC1/NAE1/GADD45A/E2F4/RAD9A/CDC25C/RAD17/STK33/TOPBP1	21
BP	GO:0006476	protein deacetylation	19/2159	93/18670	0.009326	0.2396	0.222	SPRED1/SREBF1/SUDS3/PRKD1/UCN/BCL6/SPRED2/MIER2/TBL1XR1/C6orf89/CCAR2/MTA3/IFNG/AKAP8/REST/HDAC2/MSL3/MTA2/BAZ2A	19
BP	GO:1901655	cellular response to ketone	19/2159	93/18670	0.009326	0.2396	0.222	PTGER2/ATP2B1/CFLAR/ICAM1/PTGFR/CDK4/GJB2/AQP1/PCK2/ELK1/CASP9/ERRFI1/AACS/EIF4E/NR3C1/FBXO32/AGTR2/AKAP8/SMYD3	19
BP	GO:0032479	regulation of type I interferon production	24/2159	126/18670	0.009336	0.2396	0.222	DDX3X/IKBKE/NLRX1/RELB/NFKB2/RIPK2/IRF3/NFKB1/RELA/PPM1B/CHUK/POLR3K/NLRC3/RNF135/TRAF3/HMGB2/POLR1C/TNFAIP3/TLR4/POLR3C/FLOT1/LRRFIP1/DHX33/NMI	24
BP	GO:0032350	regulation of hormone metabolic process	10/2159	38/18670	0.00941	0.2396	0.222	BMP2/EGR1/RDH10/NFKB1/TCF7L2/IFNG/CLCN2/REST/VDR/POR	10
BP	GO:0072524	pyridine-containing compound metabolic process	34/2159	195/18670	0.009433	0.2396	0.222	GPD2/ZBTB7A/NT5E/NUPR1/IDH1/RBKS/PNPO/HK1/PRKAG1/DCXR/RAE1/RPIA/FOXK2/PNP/GPD1L/PKM/ADPGK/PARP16/PFKP/NUP35/IFNG/RNLS/SEH1L/FMO2/NUP98/MDH1B/HK2/NUP153/PFKM/NUDT17/DERA/PGLS/NAMPT/IGF1	34
BP	GO:0014015	positive regulation of gliogenesis	16/2159	74/18670	0.009472	0.2396	0.222	TNFRSF1B/BMP2/LIF/HES1/CLCF1/RELA/ETV5/SOX8/ID2/NKX2-2/ZNF488/TIAM1/PRKCI/NOTCH1/CRKL/HDAC2	16
BP	GO:0043923	positive regulation by host of viral transcription	6/2159	17/18670	0.009494	0.2396	0.222	JUN/CHD1/SP1/SNW1/SMARCA4/CCNT1	6
BP	GO:0042770	signal transduction in response to DNA damage	25/2159	133/18670	0.009574	0.2397	0.2221	ABL1/SPRED1/CCNB1/BID/PAXIP1/CDKN1B/SESN2/PMAIP1/USP10/ING4/SPRED2/PCBP4/CNOT6L/CNOT6/TFDP2/CASP9/CD44/BABAM1/MUC1/GADD45A/E2F4/CDC25C/ANKRD1/STK33/DDX5	25
BP	GO:0060547	negative regulation of necrotic cell death	7/2159	22/18670	0.009698	0.2397	0.2221	BIRC3/CFLAR/CAV1/PELI1/UCN/BIRC2/SLC25A4	7
BP	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus	7/2159	22/18670	0.009698	0.2397	0.2221	BMP2/SESN2/RELA/RBPJ/NOTCH1/CARF/SMAD9	7
BP	GO:2000773	negative regulation of cellular senescence	7/2159	22/18670	0.009698	0.2397	0.2221	ABL1/BCL6/MAP3K3/HMGA2/ZKSCAN3/CDK6/NAMPT	7
BP	GO:0006625	protein targeting to peroxisome	15/2159	68/18670	0.009785	0.2397	0.2221	IDH1/CAT/ECH1/NUDT19/PEX12/EHHADH/HMGCL/MPV17/PEX16/RAB8B/PECR/PEX1/ACAA1/ZFAND6/ACOX3	15
BP	GO:0072662	protein localization to peroxisome	15/2159	68/18670	0.009785	0.2397	0.2221	IDH1/CAT/ECH1/NUDT19/PEX12/EHHADH/HMGCL/MPV17/PEX16/RAB8B/PECR/PEX1/ACAA1/ZFAND6/ACOX3	15
BP	GO:0072663	establishment of protein localization to peroxisome	15/2159	68/18670	0.009785	0.2397	0.2221	IDH1/CAT/ECH1/NUDT19/PEX12/EHHADH/HMGCL/MPV17/PEX16/RAB8B/PECR/PEX1/ACAA1/ZFAND6/ACOX3	15
BP	GO:0060412	ventricular septum morphogenesis	11/2159	44/18670	0.009907	0.2397	0.2221	RBM15/HES1/FZD2/SLIT2/ID2/HEY2/FZD1/RBPJ/FGFR2/SMAD7/NOTCH1	11
BP	GO:0002262	myeloid cell homeostasis	27/2159	147/18670	0.009924	0.2397	0.2221	ZBTB7A/LDB1/LYAR/SLC25A38/RPS24/HOXA5/NFE2L1/EPAS1/JMJD6/BCL6/ACVR2A/ID2/ADAM17/KMT2E/AMPD3/SFXN1/SH2B3/DNASE2/HMGB2/JAK2/RB1/KLF13/TMOD3/THRA/PIK3CD/SLC11A2/CDK6	27
BP	GO:0046474	glycerophospholipid biosynthetic process	37/2159	217/18670	0.009987	0.2397	0.2221	ETNK1/LPCAT1/MPPE1/SYNJ2/PIGC/PGAP2/MTMR12/DDHD1/PTPMT1/PLEKHA3/MTMR3/MFSD2A/SH3YL1/MTMR9/LCLAT1/IMPA1/GPD1L/AJUBA/ACP6/CPNE1/SBF1/INPP5F/PIP4K2A/PIGB/PIGV/PIK3CD/GPAM/PIK3C2B/PLA2G12A/MTMR7/LPCAT4/PGAP3/CDIPT/PIP5K1A/ABHD3/RUFY1/PIK3CA	37
BP	GO:0009101	glycoprotein biosynthetic process	55/2159	348/18670	0.01	0.2397	0.2221	EDEM3/AGO2/TNIP1/PHLDA1/CHST7/ST3GAL2/ALG13/B4GALT3/GLCE/TMTC3/GFPT2/B3GNT9/SLC35D1/TET1/CHST14/ST3GAL1/B3GNT2/FUT4/EOGT/TCF7L2/GCNT3/CHST10/B4GALT5/TMTC2/PLCB1/HBEGF/FUT11/FUT8/UGDH/B4GALT6/FOXL1/POMGNT1/GALNT15/GOLGA2/HS2ST1/MUC1/FAM20B/CSGALNACT2/GBGT1/EXT1/SLC35C1/GOLPH3/NUS1/CHST15/MAN1B1/ST6GALNAC1/EXTL2/MAN2A1/GXYLT2/MGAT5/PMM1/MVD/HS3ST3A1/CHST12/IGF1	55
BP	GO:0070997	neuron death	55/2159	348/18670	0.01	0.2397	0.2221	FOS/SIX1/TNFRSF1B/ABL1/JUN/EGR1/NUPR1/ADNP/GDF5/DDIT3/USP53/PARP2/MCL1/CLCF1/BID/DAXX/UCN/POLB/SLC9A1/EGLN3/FZD1/MAP3K5/KIF14/ELK1/NR4A3/BDNF/CASP9/PRKCI/CDK5R1/JAK2/NAE1/ATP13A2/BCL2L1/TP63/RB1/TLR4/IFNG/LANCL1/HSF1/ZPR1/NR4A2/STAMBP/PICALM/APAF1/REST/FYN/RASA1/CLN3/HRAS/PIK3CA/STXBP1/LIG4/TSC1/ADARB1/NAMPT	55
BP	GO:0018393	internal peptidyl-lysine acetylation	29/2159	161/18670	0.01013	0.2397	0.2221	BAZ1A/LIF/LDB1/TAF5L/JADE1/KANSL1L/PAXIP1/MRGBP/CPA4/PHF20/MSL1/ING4/JADE3/BEND3/DPF2/KAT6A/TAF6L/KANSL1/MUC1/TADA2A/TAF12/DMAP1/TRIM16/POR/TAF5/HAT1/SUPT7L/MSL3/POLE3	29
BP	GO:0002931	response to ischemia	12/2159	50/18670	0.01013	0.2397	0.2221	MAP2K6/EGR1/CAV1/GJB2/PANX1/PPIF/MAP3K5/CASP9/ARID1B/RNLS/REST/HK2	12
BP	GO:0046854	phosphatidylinositol phosphorylation	12/2159	50/18670	0.01013	0.2397	0.2221	PIP5KL1/SOCS5/SOCS3/IMPA1/SOCS7/IMPAD1/PIP4K2A/FAM126A/PIK3CD/PIK3C2B/PIP5K1A/PIK3CA	12
BP	GO:0070671	response to interleukin-12	12/2159	50/18670	0.01013	0.2397	0.2221	MTAP/RIPK2/GSTO1/TYK2/PLCB1/LMNB1/CNN2/SERPINB2/PAK2/JAK2/IFNG/IL12A	12
BP	GO:0030041	actin filament polymerization	32/2159	182/18670	0.01023	0.2401	0.2224	VILL/MSRB2/ARHGAP28/ICAM1/DIAPH1/ARF6/SLIT2/TMOD2/JMY/RHOBTB1/ARPC5L/ARPC5/GMFB/FMN2/PFN4/EVL/ARPC2/MYO1C/FCHSD2/RICTOR/JAK2/PFN2/ARPC4/VASP/TMOD3/TRIOBP/MSRB1/PREX1/WASL/RASA1/CDC42EP2/SPTA1	32
BP	GO:0061138	morphogenesis of a branching epithelium	32/2159	182/18670	0.01023	0.2401	0.2224	SIX1/BMP2/MKS1/ABL1/SPRY2/RBM15/MMP14/HOXA11/SLIT2/FGF1/EPHA2/RDH10/FEM1B/HOXA5/ETV5/SOX8/FGF7/SOCS3/PGF/FGFR2/FOXC2/FAT4/YAP1/FGFR1/TP63/NOTCH1/AGTR2/PBX1/FOXF1/VDR/MAGED1/PGR	32
BP	GO:0006650	glycerophospholipid metabolic process	51/2159	319/18670	0.01031	0.2403	0.2227	ETNK1/LPCAT1/MPPE1/SYNJ2/ALDH5A1/PIGC/PGAP2/ABHD4/MTMR12/DDHD1/PTPMT1/PIP5KL1/SERAC1/PLEKHA3/MTMR3/MFSD2A/SOCS5/SH3YL1/MTMR9/LCLAT1/PLCB1/SOCS3/IMPA1/GPD1L/ENPP6/AJUBA/ACP6/SOCS7/CPNE1/SBF1/IMPAD1/INPP5F/PIP4K2A/FAM126A/PIGB/PDGFRB/PIGV/INPP5B/PIK3CD/GPAM/PIK3C2B/PLA2G12A/MTMR7/LPCAT4/PGAP3/CDIPT/PIP5K1A/ABHD3/RUFY1/GALR2/PIK3CA	51
BP	GO:0110110	positive regulation of animal organ morphogenesis	17/2159	81/18670	0.01032	0.2403	0.2227	SIX1/BMP2/LIF/HOXA11/CFLAR/FGF1/JAG1/SOX8/FGF7/RBPJ/FGFR2/TNFAIP3/FGFR1/NOTCH1/AGTR2/VDR/MAGED1	17
BP	GO:2000116	regulation of cysteine-type endopeptidase activity	40/2159	239/18670	0.01037	0.2404	0.2227	BIRC3/TNFAIP8/DDX3X/CFLAR/RIPK2/TNFRSF10A/BID/CD27/AQP1/PMAIP1/CDKN2D/CASP4/RPS6KA3/TNFRSF10B/EGLN3/PDCD5/TNFSF15/MAP3K5/PLAUR/TNFSF10/CASP9/CD44/HSPE1/CAAP1/AIM2/PAK2/JAK2/PRDX5/TP63/KHDC1/HSF1/ST20/APAF1/PPM1F/REST/FYN/BIRC2/POR/PCID2/CASC2	40
BP	GO:0006029	proteoglycan metabolic process	19/2159	94/18670	0.01045	0.2404	0.2227	BMP2/CHST7/GLCE/SLC35D1/CHST14/TCF7L2/CHST10/UGDH/FOXL1/HS2ST1/FAM20B/CSGALNACT2/IMPAD1/EXT1/CHST15/EXTL2/HS3ST3A1/CHST12/IGF1	19
BP	GO:0000302	response to reactive oxygen species	39/2159	232/18670	0.0105	0.2404	0.2227	FOSL1/FOS/ABL1/DUSP1/JUN/CFLAR/ERCC6/CAT/KPNA4/PDK2/AQP1/GCH1/SESN2/RELA/PPIF/SESN3/APEX1/ADA/CAMKK2/SPHK1/CHUK/TXNIP/MAP3K5/NR4A3/OSER1/PPP2CB/MPV17/ECT2/TNFAIP3/PRDX5/TRPA1/PDGFRB/IMPACT/HSF1/GLRX2/SETX/FYN/HDAC2/ZNF580	39
BP	GO:0034330	cell junction organization	47/2159	290/18670	0.01053	0.2404	0.2227	ABL1/MAP4K4/SLK/CBFB/MACF1/MMP14/LDB1/ITGA2/ARF6/PEAK1/CAV1/EPHA2/GJB2/DUSP3/F2RL1/TJP1/HIPK1/PARD3/BCAS3/MPP7/SLC9A1/CTNND2/FLNC/RASSF8/PTK2/SDC4/AJUBA/LIMS2/TRIP6/MYO1C/PRKCI/PLEC/ECT2/CCM2/VASP/SMAD7/CADM1/MTDH/RHOC/RAB8B/WDR1/FLOT1/PPM1F/PIP5K1A/PRKACA/PHLDB2/TSC1	47
BP	GO:0002756	MyD88-independent toll-like receptor signaling pathway	9/2159	33/18670	0.01058	0.2404	0.2227	BIRC3/IKBKE/TANK/IRF3/RAB11FIP2/CHUK/TRAF3/TLR4/BIRC2	9
BP	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	9/2159	33/18670	0.01058	0.2404	0.2227	CDKN1C/HEXIM2/CDKN1B/CDKN2D/NR2F2/CDKN2C/TNFAIP3/CEBPA/CDKN2B	9
BP	GO:0001649	osteoblast differentiation	38/2159	225/18670	0.01062	0.2404	0.2227	BMP2/RSL1D1/CBFB/TWIST2/ASF1A/CAT/EPHA2/JAG1/WWTR1/CLIC1/PRKD1/SOX8/PSMC2/ACVR2A/ID2/SATB2/FZD1/PTK2/MEF2D/FGFR2/SEMA7A/HSPE1/PTHLH/TP63/CEBPA/NOTCH1/ID3/MYBBP1A/JUNB/REST/SH3PXD2B/DDX21/CDK6/HOXA2/PRKACA/TMEM119/DDX5/IGF1	38
BP	GO:0008643	carbohydrate transport	27/2159	148/18670	0.01084	0.2404	0.2227	GRB10/SLC35D1/SLC2A10/APPL2/AQP1/YES1/SESN2/SLC5A3/MFSD2A/SLC2A11/TMEM144/C2CD5/SLC2A3/NR4A3/ENPP1/SLC37A4/PRKCI/SLC50A1/SLC45A1/SLC35B4/SLC23A2/RHOQ/SLC35C1/SLC35A2/HK2/TSC1/IGF1	27
BP	GO:0035148	tube formation	27/2159	148/18670	0.01084	0.2404	0.2227	SIX1/MKS1/ABL1/IFT172/FZD2/LIAS/HOXA1/LMO4/SOX8/BCAS3/DEAF1/DVL3/FZD1/DVL2/SDC4/FGFR2/PHACTR4/LUZP1/VASP/NOTCH1/IFT52/APAF1/SEC24B/CC2D2A/PRKACA/SDCCAG8/TSC1	27
BP	GO:2001236	regulation of extrinsic apoptotic signaling pathway	28/2159	155/18670	0.01094	0.2404	0.2227	G0S2/CFLAR/ICAM1/MCL1/CAV1/TNFRSF10A/BID/FEM1B/TCF7L2/PMAIP1/RELA/TNFRSF10B/ITPRIP/TRAF1/TNFSF10/TNFRSF12A/YAP1/PAK2/HMGB2/TNFAIP3/BCL2L1/FGFR1/AGTR2/EYA4/FYN/DEPTOR/PELI3/IGF1	28
BP	GO:0090068	positive regulation of cell cycle process	48/2159	298/18670	0.01097	0.2404	0.2227	DDX3X/CCND1/DBF4/CCNB1/CRLF3/CDK4/CDKN1B/ID2/ADAM17/KMT2E/APEX1/PLCB1/PCBP4/EREG/RAB11A/SPHK1/GPSM2/CNOT6L/KIF14/CNOT6/HMGA2/TFDP2/FEN1/GIPC1/NSMCE2/CUL3/CDK5R1/DDX11/ECT2/MUC1/GADD45A/MTA3/RAD51C/FGFR1/CEP120/RB1/PDGFRB/MYBBP1A/TMOD3/CCND3/PBX1/E2F4/CDC25C/RAD21/PCID2/CDC7/PRKACA/IGF1	48
BP	GO:0016073	snRNA metabolic process	20/2159	101/18670	0.01099	0.2404	0.2227	ZNF143/ZC3H8/NABP1/POLR2I/EXOSC8/INTS2/GTF2F2/SRRT/POU2F2/SP1/ELL/POLR2G/NOP10/POU2F1/RPRD1A/EXOSC4/TAF5/CCNT1/ICE2/EXOSC10	20
BP	GO:0140053	mitochondrial gene expression	29/2159	162/18670	0.01101	0.2404	0.2227	MRPL40/TFAM/RMND1/NOA1/TBRG4/DARS2/MRPS6/OXA1L/MTIF2/UQCC1/MRPS18C/MRPL17/MRPS14/TRMT10C/MRPS18A/NGRN/MTRF1L/MRPL11/MRPL10/MRPS16/RPUSD4/MRPL24/MRPS33/MRPS31/LARS2/MRRF/TRMT5/MRPS36/MRPL2	29
BP	GO:0043574	peroxisomal transport	15/2159	69/18670	0.0112	0.2404	0.2227	IDH1/CAT/ECH1/NUDT19/PEX12/EHHADH/HMGCL/MPV17/PEX16/RAB8B/PECR/PEX1/ACAA1/ZFAND6/ACOX3	15
BP	GO:0016311	dephosphorylation	72/2159	478/18670	0.01128	0.2404	0.2227	DUSP6/BMP2/PPP2R2A/DUSP1/SPRED1/SH2D4A/DUSP5/MINPP1/NT5E/CSRNP2/ITGA2/CDK5RAP3/PDP2/TSKS/SYNJ2/BOD1L2/RNGTT/DUSP3/PTPMT1/PPP1R3E/MTMR3/FAM220A/POLB/PTPN12/PPP1R14C/APEX1/SGPP1/MTMR9/PPM1H/PPM1B/DUSP7/IMPA1/PHOSPHO2/PHACTR4/MAGI2/DUSP28/ACP6/PPP6R1/PPME1/PPP2CB/JAK2/PPEF1/SBF1/PPP4R4/IMPAD1/INPP5F/SLC39A10/UBASH3B/SYTL2/ELL/IFNG/PDGFRB/AGTR2/INPP5B/PPTC7/PPM1F/STYXL1/DUSP27/EYA4/MTMR7/ACPP/RPRD1A/CDC25C/MGAT5/PPP3CC/DUSP19/CTTNBP2NL/PDP1/THNSL2/ACP2/TSC1/PPM1G	72
BP	GO:0032606	type I interferon production	24/2159	128/18670	0.01131	0.2404	0.2227	DDX3X/IKBKE/NLRX1/RELB/NFKB2/RIPK2/IRF3/NFKB1/RELA/PPM1B/CHUK/POLR3K/NLRC3/RNF135/TRAF3/HMGB2/POLR1C/TNFAIP3/TLR4/POLR3C/FLOT1/LRRFIP1/DHX33/NMI	24
BP	GO:1902229	regulation of intrinsic apoptotic signaling pathway in response to DNA damage	10/2159	39/18670	0.01137	0.2404	0.2227	CXCL12/ACKR3/BID/CDKN2D/CD44/MUC1/CCAR2/BCL2L1/RAD9A/HNRNPK	10
BP	GO:0002237	response to molecule of bacterial origin	54/2159	343/18670	0.01144	0.2404	0.2227	BDKRB1/FOS/TNFRSF1B/PTGER2/ABL1/LOXL1/JUN/TRIM6/CD274/FOXP1/NFKBIL1/NFKB2/ICAM1/RIPK2/LIAS/IL1RN/PTGFR/CDK4/IRF3/TRIB1/GJB2/PELI1/IFNAR1/NFKB1/GCH1/RELA/THBD/RPS6KA3/ADAM17/PDE4D/CHUK/FGFR2/CASP9/HMGB2/JAK2/TNFAIP3/IRGM/PDCD1LG2/TLR4/IRAK2/IL36RN/NOTCH1/CD24/HSF1/MTDH/AKAP8/NFKBIB/JUNB/IL12A/HDAC2/ANKRD1/GJB6/IL36B/MGST2	54
BP	GO:0001889	liver development	25/2159	135/18670	0.01152	0.2404	0.2227	CCND1/JUN/CFLAR/ITGA2/HES1/ARF6/PTCD2/DBP/RELA/ADA/PCK2/MPST/GNPNAT1/LIMS2/PKM/HMGCL/CUL3/UPF2/AACS/TNFAIP3/CEBPA/NOTCH1/QDPR/MAN2A1/PIK3CA	25
BP	GO:0007568	aging	51/2159	321/18670	0.01157	0.2404	0.2227	FOS/TNFRSF1B/POLG/ABL1/ATP2B1/HMGA1/RSL1D1/SREBF1/JUN/NFKB2/ICAM1/CAT/ARG2/CDKN1C/RAD54L/GJB2/BCL2A1/DNMT3A/KRT16/MAPKAPK5/RELA/BCL6/POLB/ID2/ABAT/MAP3K3/MAP2K1/APEX1/ADA/PDE4D/COX1/KAT6A/HMGA2/ZKSCAN3/CASP9/NSMCE2/COQ7/TP63/PDGFRB/GLRX2/PICALM/APAF1/IGFBP1/YPEL3/CDKN2B/TBX2/GJB6/CDK6/HRAS/WRN/NAMPT	51
BP	GO:0071375	cellular response to peptide hormone stimulus	51/2159	321/18670	0.01157	0.2404	0.2227	ATP2B1/GHR/SREBF1/ATP6V1E2/CFLAR/GRB10/CAV1/CDK4/GJB2/PDK2/APPL2/NFKB1/RELA/PRKCZ/SESN3/SLC9A1/APEX1/C2CD5/GKAP1/PCK2/SHC1/SOCS3/PTK2/FOXC2/PKM/NR4A3/AGTRAP/MYO1C/ENPP1/ERRFI1/PRKCI/PRKAR1A/ARID1B/JAK2/SP1/AGTR2/ATP6V1B2/RHOQ/HSF1/CCND3/RAB8B/NR4A2/CPEB1/MYO5A/IGFBP1/FYN/POR/PRKAR2A/PRKACA/PIK3CA/TSC1	51
BP	GO:0018146	keratan sulfate biosynthetic process	8/2159	28/18670	0.0117	0.2404	0.2227	ST3GAL2/B4GALT3/CHST2/ST3GAL1/B3GNT2/B4GALT5/B4GALT6/OMD	8
BP	GO:0021846	cell proliferation in forebrain	8/2159	28/18670	0.0117	0.2404	0.2227	AKNA/DOCK7/HOOK3/KIF14/FGFR2/EMX2/FGFR1/CEP120	8
BP	GO:0036296	response to increased oxygen levels	8/2159	28/18670	0.0117	0.2404	0.2227	POLG/CAT/CAV1/CDK4/POLB/CCDC115/PDGFRB/HDAC2	8
BP	GO:0052312	modulation of transcription in other organism involved in symbiotic interaction	8/2159	28/18670	0.0117	0.2404	0.2227	JUN/CHD1/HMGA2/SP1/SNW1/SMARCA4/REST/CCNT1	8
BP	GO:0032570	response to progesterone	11/2159	45/18670	0.01178	0.2404	0.2227	FOSL1/FOS/ABHD2/PTGER2/SREBF1/CAV1/GJB2/RELA/NKX2-2/TXNIP/YAP1	11
BP	GO:0032612	interleukin-1 production	22/2159	115/18670	0.01184	0.2404	0.2227	S1PR3/EGR1/FOXP1/RIPK2/ARG2/HK1/F2RL1/PANX1/SERPINB1/SPHK1/ERRFI1/AIM2/JAK2/TNFAIP3/TLR4/IFNG/CPTP/HSPB1/MR1/HDAC2/TRIM16/IGF1	22
BP	GO:1904375	regulation of protein localization to cell periphery	22/2159	115/18670	0.01184	0.2404	0.2227	MMP14/ARF6/EPHA2/RAB11FIP2/PRKCZ/VPS4A/RHOG/STAC/RAB11A/GPSM2/PRKCI/KIF5B/BCL2L1/IFNG/NKD2/AP2M1/RHOQ/EPHB2/MISP/PICALM/HRAS/EPB41L2	22
BP	GO:0060271	cilium assembly	57/2159	366/18670	0.01186	0.2404	0.2227	MKS1/FAM161A/TTLL1/IFT172/EHD1/CCDC113/MNS1/B9D1/WWTR1/ARMC9/POC1B/DNAL1/ARL13B/IFT88/TMEM138/BBS10/C5orf30/NEK1/ODF2/RAB11A/TUBB4B/CBY1/HAUS5/TTC30B/SNX10/CEP70/CEP57/IFT46/UNC119B/MAPRE1/HAUS6/INTU/TMEM17/CSNK1E/ASAP1/IFT74/ARL6/CEP120/RPGR/RAB23/BBS2/NOTCH1/IFT52/DCDC2/E2F4/TMEM231/NME5/TUBA4A/GAS8/TMEM80/EXOC5/CC2D2A/RILPL2/PRKACA/CEP89/SDCCAG8/HAUS3	57
BP	GO:0016573	histone acetylation	28/2159	156/18670	0.01191	0.2404	0.2227	BAZ1A/LIF/LDB1/TAF5L/JADE1/KANSL1L/PAXIP1/MRGBP/CPA4/PHF20/MSL1/ING4/JADE3/BEND3/DPF2/KAT6A/TAF6L/KANSL1/MUC1/TADA2A/TAF12/DMAP1/TRIM16/TAF5/HAT1/SUPT7L/MSL3/POLE3	28
BP	GO:0010870	positive regulation of receptor biosynthetic process	5/2159	13/18670	0.01191	0.2404	0.2227	HOXA5/JAK2/IFNG/HNRNPK/HDAC2	5
BP	GO:0014842	regulation of skeletal muscle satellite cell proliferation	5/2159	13/18670	0.01191	0.2404	0.2227	SIX1/CFLAR/AKIRIN1/JAK2/PAXBP1	5
BP	GO:0031953	negative regulation of protein autophosphorylation	5/2159	13/18670	0.01191	0.2404	0.2227	JUN/CAV1/ENPP1/ERRFI1/IMPACT	5
BP	GO:0046349	amino sugar biosynthetic process	5/2159	13/18670	0.01191	0.2404	0.2227	UAP1/GFPT2/GNE/UAP1L1/GNPNAT1	5
BP	GO:0070071	proton-transporting two-sector ATPase complex assembly	5/2159	13/18670	0.01191	0.2404	0.2227	ATPAF1/OXA1L/VMA21/ATPAF2/CCDC115	5
BP	GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	5/2159	13/18670	0.01191	0.2404	0.2227	RIPK2/RELA/TNFAIP3/IRGM/TLR4	5
BP	GO:0071027	nuclear RNA surveillance	5/2159	13/18670	0.01191	0.2404	0.2227	EXOSC8/DXO/EXOSC4/PCID2/EXOSC10	5
BP	GO:0071028	nuclear mRNA surveillance	5/2159	13/18670	0.01191	0.2404	0.2227	EXOSC8/DXO/EXOSC4/PCID2/EXOSC10	5
BP	GO:0072182	regulation of nephron tubule epithelial cell differentiation	5/2159	13/18670	0.01191	0.2404	0.2227	LIF/WWTR1/FAT4/YAP1/CD24	5
BP	GO:0090308	regulation of methylation-dependent chromatin silencing	5/2159	13/18670	0.01191	0.2404	0.2227	ATF7IP/DNMT1/TET1/SETDB1/ZNF304	5
BP	GO:1905477	positive regulation of protein localization to membrane	23/2159	122/18670	0.01216	0.2418	0.2241	ARF6/EPHA2/RAB11FIP2/BID/PMAIP1/C2CD5/RHOG/STAC/RAB11A/PDCD5/TFDP2/MYO1C/PRKCI/CDK5R1/KIF5B/TP63/IFNG/NKD2/EPHB2/FYN/PPP3CC/MIEF2/HRAS	23
BP	GO:1901264	carbohydrate derivative transport	16/2159	76/18670	0.01223	0.2418	0.2241	SLC35D1/GLTP/MFSD2A/ADA/SLC10A7/SLC37A4/SLC50A1/SLC35B4/SYTL2/SLC25A25/SLC35C1/SLC25A17/SLC35A2/SLC35E3/SLC25A4/CALHM1	16
BP	GO:0001823	mesonephros development	20/2159	102/18670	0.01223	0.2418	0.2241	SIX1/BMP2/OSR2/HOXA11/HES1/SLIT2/FGF1/CAT/ARG2/SOX8/SDC4/PGF/FGFR2/FOXC2/FAT4/FGFR1/SMAD7/AGTR2/PBX1/MAGED1	20
BP	GO:0006900	vesicle budding from membrane	20/2159	102/18670	0.01223	0.2418	0.2241	VAPB/SEC23IP/PEF1/TRAPPC6A/KLHL12/VPS4A/VAPA/SEC24A/PRKCI/PPP6R1/CUL3/SEC31B/GOLGA2/TRAPPC2L/DNM3/AP2M1/GOLPH3/PICALM/SEC24B/WASL	20
BP	GO:0050730	regulation of peptidyl-tyrosine phosphorylation	42/2159	256/18670	0.01226	0.2418	0.2241	ABL1/GHR/LIF/ADNP/ITGB3/HES1/ICAM1/ERCC6/RIPK2/CAV1/CLCF1/YES1/VPS25/PRKCZ/SOCS5/TEC/FGF7/ADAM17/SHC1/SOCS3/HBEGF/EREG/IL11/DVL2/BDNF/SH2B3/CD44/ERRFI1/RICTOR/PAK2/JAK2/IL22RA2/INPP5F/DLG4/IFNG/CD24/HSF1/IL12A/FYN/HDAC2/EPHA4/IGF1	42
BP	GO:0071560	cellular response to transforming growth factor beta stimulus	41/2159	249/18670	0.01247	0.2418	0.2241	FOS/ZBTB7A/JUN/GDF5/CFLAR/CAV1/NRROS/LEMD3/CDKN1C/SMURF2/APPL2/YES1/PRKCZ/BCL9L/PARD3/ACVR2A/ADAM17/RNF111/PTK2/PDCD5/TGFB1I1/FUT8/ZYX/FGFR2/GIPC1/NREP/FURIN/NR3C1/SNW1/PRDM16/SMAD7/GLG1/APAF1/FYN/CRKL/CDKN2B/HDAC2/ANKRD1/NLK/EMILIN1/SMAD9	41
BP	GO:1902749	regulation of cell cycle G2/M phase transition	36/2159	213/18670	0.01248	0.2418	0.2241	CCND1/CCNB1/CDK5RAP3/CDK4/PSME4/PAXIP1/PSMC2/VPS4A/ODF2/RAB11A/TUBB4B/HAUS5/KIF14/DONSON/HMGA2/CEP70/CEP57/BABAM1/MAPRE1/HAUS6/PSMD4/CSNK1E/NAE1/MTA3/RAD51C/ATF5/PBX1/TUBA4A/CDC25C/RAD21/RAD17/CDC7/PRKACA/TOPBP1/SDCCAG8/HAUS3	36
BP	GO:0031098	stress-activated protein kinase signaling cascade	50/2159	315/18670	0.01253	0.2418	0.2241	MAP2K6/BMP2/HIPK3/MAP4K4/DUSP1/SLK/GADD45G/ERCC6/RIPK2/IL1RN/TAB3/TRIB1/CD27/DUSP3/F2RL1/NFKB1/TNFSF11/DAXX/PJA2/MAP3K3/DVL3/MAP2K1/NEK1/PLCB1/MAP4K5/SPHK1/DVL2/ZNF622/CHUK/MAP3K5/TIAM1/IRAK4/UBE2N/PAK2/GADD45A/GADD45B/CCM2/TLR4/MAP4K3/IRAK2/MID1/IL36RN/ROR2/DTNBP1/STK10/CRKL/DUSP19/EPHA4/HRAS/IL36B	50
BP	GO:0042451	purine nucleoside biosynthetic process	7/2159	23/18670	0.01258	0.2418	0.2241	MTAP/NT5E/IMPDH2/ADA/NME5/NME3/NME6	7
BP	GO:0046129	purine ribonucleoside biosynthetic process	7/2159	23/18670	0.01258	0.2418	0.2241	MTAP/NT5E/IMPDH2/ADA/NME5/NME3/NME6	7
BP	GO:0072215	regulation of metanephros development	7/2159	23/18670	0.01258	0.2418	0.2241	LIF/EGR1/WWTR1/FAT4/YAP1/PDGFRB/AGTR2	7
BP	GO:0072337	modified amino acid transport	7/2159	23/18670	0.01258	0.2418	0.2241	SLC19A2/CTNS/SLC1A4/SLC22A5/SLC38A2/SLC25A32/SLC46A1	7
BP	GO:0106106	cold-induced thermogenesis	26/2159	143/18670	0.01276	0.2418	0.2241	MAP2K6/PRKAB2/IL4R/GADD45G/G0S2/DDIT3/GRB10/CAV1/TLE3/APPL2/DOCK7/EPAS1/ADAM17/ELOVL6/RBPJ/ACOT13/FOXC2/JAK2/RB1/OMA1/TLR4/PRDM16/NOTCH1/HSF1/THRA/HOXC10	26
BP	GO:0120161	regulation of cold-induced thermogenesis	26/2159	143/18670	0.01276	0.2418	0.2241	MAP2K6/PRKAB2/IL4R/GADD45G/G0S2/DDIT3/GRB10/CAV1/TLE3/APPL2/DOCK7/EPAS1/ADAM17/ELOVL6/RBPJ/ACOT13/FOXC2/JAK2/RB1/OMA1/TLR4/PRDM16/NOTCH1/HSF1/THRA/HOXC10	26
BP	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	33/2159	192/18670	0.01281	0.2418	0.2241	ABL1/GHR/LIF/ADNP/ITGB3/HES1/ICAM1/ERCC6/RIPK2/CLCF1/YES1/TEC/FGF7/ADAM17/SOCS3/HBEGF/EREG/IL11/DVL2/BDNF/CD44/RICTOR/PAK2/JAK2/DLG4/IFNG/CD24/HSF1/IL12A/FYN/HDAC2/EPHA4/IGF1	33
BP	GO:0046777	protein autophosphorylation	39/2159	235/18670	0.01286	0.2418	0.2241	ABL1/SLK/ULK1/JUN/EPHB3/MKNK2/PEAK1/MEX3B/CLK4/CAV1/MOB1B/PRKD1/YES1/MAPKAPK5/TEC/RAD50/MAP3K3/CAMKK2/PTK2/FGFR2/ENPP1/CDK12/ERRFI1/PAK2/JAK2/MARK3/ATP13A2/FGFR1/PDGFRB/IMPACT/FYN/STK10/PIM3/STK33/EPHA4/AAK1/PRKACA/NLK/VEGFC	39
BP	GO:0035994	response to muscle stretch	6/2159	18/18670	0.01287	0.2418	0.2241	FOS/JUN/NFKB1/RELA/SLC9A1/ANKRD1	6
BP	GO:0060192	negative regulation of lipase activity	6/2159	18/18670	0.01287	0.2418	0.2241	ABL1/ANGPTL4/APOC3/RGS2/BICD1/POR	6
BP	GO:0060546	negative regulation of necroptotic process	6/2159	18/18670	0.01287	0.2418	0.2241	BIRC3/CFLAR/CAV1/PELI1/BIRC2/SLC25A4	6
BP	GO:0060977	coronary vasculature morphogenesis	6/2159	18/18670	0.01287	0.2418	0.2241	SGCD/SPRED1/HEY2/NOTCH1/PDGFRB/SEC24B	6
BP	GO:1905276	regulation of epithelial tube formation	6/2159	18/18670	0.01287	0.2418	0.2241	SIX1/FZD2/DVL3/FZD1/DVL2/SEC24B	6
BP	GO:0048754	branching morphogenesis of an epithelial tube	27/2159	150/18670	0.01287	0.2418	0.2241	SIX1/BMP2/MKS1/ABL1/SPRY2/RBM15/MMP14/HOXA11/SLIT2/FGF1/EPHA2/RDH10/HOXA5/ETV5/SOX8/PGF/FGFR2/FOXC2/FAT4/YAP1/NOTCH1/AGTR2/PBX1/FOXF1/VDR/MAGED1/PGR	27
BP	GO:0010922	positive regulation of phosphatase activity	9/2159	34/18670	0.01295	0.2418	0.2241	BMP2/ITGA2/MTMR9/MAGI2/JAK2/SLC39A10/IFNG/PDGFRB/AGTR2	9
BP	GO:0043276	anoikis	9/2159	34/18670	0.01295	0.2418	0.2241	MCL1/CAV1/PTRH2/PTK2/ZNF304/NOTCH1/MYBBP1A/ANKRD13C/PIK3CA	9
BP	GO:0097327	response to antineoplastic agent	19/2159	96/18670	0.01304	0.2424	0.2246	EGR1/CFLAR/ICAM1/CDK4/GJB2/AQP1/DAXX/PCK2/KDM3B/CASP9/ERRFI1/DDX11/EIF4E/NR3C1/FBXO32/AGTR2/HSF1/PTGR1/SMYD3	19
BP	GO:0007569	cell aging	22/2159	116/18670	0.01306	0.2424	0.2246	ABL1/HMGA1/RSL1D1/ICAM1/ARG2/MAPKAPK5/BCL6/ID2/MAP3K3/MAP2K1/KAT6A/HMGA2/ZKSCAN3/NSMCE2/TP63/YPEL3/CDKN2B/TBX2/CDK6/HRAS/WRN/NAMPT	22
BP	GO:0007254	JNK cascade	36/2159	214/18670	0.01338	0.2476	0.2294	HIPK3/MAP4K4/GADD45G/ERCC6/RIPK2/IL1RN/TAB3/TRIB1/CD27/DUSP3/F2RL1/TNFSF11/DAXX/PJA2/DVL3/PLCB1/MAP4K5/DVL2/ZNF622/MAP3K5/TIAM1/IRAK4/UBE2N/GADD45A/GADD45B/TLR4/MAP4K3/IRAK2/IL36RN/ROR2/DTNBP1/CRKL/DUSP19/EPHA4/HRAS/IL36B	36
BP	GO:0032652	regulation of interleukin-1 production	20/2159	103/18670	0.01358	0.249	0.2307	S1PR3/EGR1/FOXP1/RIPK2/ARG2/HK1/PANX1/SERPINB1/SPHK1/ERRFI1/AIM2/JAK2/TNFAIP3/TLR4/IFNG/CPTP/HSPB1/HDAC2/TRIM16/IGF1	20
BP	GO:0006734	NADH metabolic process	10/2159	40/18670	0.01363	0.249	0.2307	GPD2/HK1/FOXK2/PKM/ADPGK/PFKP/MDH1B/HK2/PFKM/NUDT17	10
BP	GO:0060997	dendritic spine morphogenesis	13/2159	58/18670	0.01364	0.249	0.2307	EPHB3/DOCK10/CTNND2/SIPA1L1/TIAM1/CDK5R1/DLG4/DNM3/EPHB2/CAPRIN1/WASL/PDLIM5/EPHA4	13
BP	GO:0006399	tRNA metabolic process	33/2159	193/18670	0.01379	0.249	0.2307	ELP4/PUS10/TRMT6/TP53RK/OSGEPL1/PSTK/VARS2/DARS2/SEPHS2/BCDIN3D/NSUN2/HARS2/ELAC1/EXOSC8/POLR3K/LSM6/TRMT10C/MARS2/TYW1/DTD1/LCMT2/FAM98B/RPUSD4/TRMT1L/SEPHS1/OSGEP/QTRT1/LARS2/TRMT5/PRORSD1P/TRMU/EXOSC10/DUS1L	33
BP	GO:1901654	response to ketone	33/2159	193/18670	0.01379	0.249	0.2307	FOSL1/FOS/ABHD2/PTGER2/CCND1/ATP2B1/DUSP1/SREBF1/CFLAR/ICAM1/SLIT2/PTGFR/CAV1/CDK4/GJB2/AQP1/RELA/NKX2-2/PCK2/TXNIP/ELK1/CASP9/ERRFI1/YAP1/AACS/EIF4E/BCL2L1/NR3C1/FBXO32/AGTR2/HSF1/AKAP8/SMYD3	33
BP	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	16/2159	77/18670	0.01383	0.249	0.2307	AGO2/DCP1A/PAN2/PAN3/MLH1/EXOSC8/CNOT6L/PARN/CNOT6/LSM6/TNRC6A/POLR2G/LSM2/TTC37/EXOSC4/LSM4	16
BP	GO:0032481	positive regulation of type I interferon production	16/2159	77/18670	0.01383	0.249	0.2307	DDX3X/NFKB2/RIPK2/IRF3/NFKB1/RELA/CHUK/POLR3K/RNF135/HMGB2/POLR1C/TLR4/POLR3C/FLOT1/LRRFIP1/DHX33	16
BP	GO:0001843	neural tube closure	18/2159	90/18670	0.01387	0.249	0.2307	MKS1/ABL1/IFT172/FZD2/LIAS/LMO4/DEAF1/DVL3/FZD1/DVL2/SDC4/PHACTR4/VASP/APAF1/SEC24B/CC2D2A/PRKACA/TSC1	18
BP	GO:0022900	electron transport chain	32/2159	186/18670	0.01389	0.249	0.2307	GPD2/CCNB1/ETFB/SLC25A22/ALDH5A1/PHGDH/NDUFV2/COX15/GLRX/BID/NDUFA6/NDUFB5/COX1/AKR1A1/COX11/DMGDH/DEGS1/MYBBP1A/DHRS3/NDUFS3/UQCR10/GLRX2/QDPR/NDUFV1/NDUFS2/ISCU/POR/SH3BGRL3/NDUFB10/NDUFA11/SURF1/D2HGDH	32
BP	GO:0050706	regulation of interleukin-1 beta secretion	11/2159	46/18670	0.0139	0.249	0.2307	FOXP1/RIPK2/ARG2/HK1/PANX1/SERPINB1/AIM2/TNFAIP3/TLR4/CPTP/TRIM16	11
BP	GO:0043406	positive regulation of MAP kinase activity	42/2159	258/18670	0.01391	0.249	0.2307	DUSP6/MAP2K6/BMP2/GHR/DUSP5/GADD45G/ERCC6/RIPK2/FGF1/TAB3/TNFSF11/DAXX/MAPKAPK5/MAP3K3/DVL3/MAP2K1/SHC1/DUSP7/MAP4K5/DVL2/LAMTOR3/MAP3K5/AJUBA/TIAM1/UBE2N/JAK2/GADD45A/GADD45B/FGFR1/TLR4/MAP4K3/IRAK2/CD24/PDGFRB/ROR2/CRKL/AVPI1/DUSP19/MAGED1/EPHA4/HRAS/IGF1	42
BP	GO:0008064	regulation of actin polymerization or depolymerization	31/2159	179/18670	0.01397	0.2492	0.2309	VILL/ARHGAP28/ICAM1/ARF6/SLIT2/TMOD2/CXCL12/JMY/F2RL1/RHOBTB1/ARPC5L/ARPC5/GMFB/FMN2/PFN4/EVL/ARPC2/MYO1C/FCHSD2/RICTOR/PFN2/ARPC4/VASP/TMOD3/TRIOBP/PREX1/WDR1/WASL/RASA1/CDC42EP2/SPTA1	31
BP	GO:0032508	DNA duplex unwinding	21/2159	110/18670	0.01402	0.2492	0.2309	DDX3X/HMGA1/RECQL/CHD2/ERCC6/CHD1/RAD50/CHD9/MCM9/RAD54B/GTF2F2/DDX11/POT1/RAD54L2/SETX/RPA1/GTF2H5/HELQ/CHD1L/ERCC6L/WRN	21
BP	GO:0007093	mitotic cell cycle checkpoint	29/2159	165/18670	0.01405	0.2492	0.2309	CCND1/DUSP1/CCNB1/CDK5RAP3/NABP1/RFWD3/CDKN1B/VPS4A/PCBP4/CNOT6L/RPA2/CNOT6/DONSON/HMGA2/TFDP2/MUC1/NAE1/GADD45A/BCL2L1/RB1/E2F4/RAD9A/CDC25C/RAD17/CDKN2B/STK33/PCID2/HRAS/TOPBP1	29
BP	GO:0016236	macroautophagy	47/2159	295/18670	0.01418	0.2508	0.2324	PRKAB2/ULK1/NUPR1/ATP6V1E2/RIPK2/LRSAM1/PRKAG1/EPM2A/SESN2/VPS25/MTMR3/IFT88/RALB/SESN3/VPS4A/LAMTOR3/TEX264/ATG101/KLHL3/GABARAPL1/MFN1/LAMTOR4/VPS37A/MLST8/SNAPIN/CDK5R1/ATP13A2/IRGM/SPTLC2/PIP4K2A/RAB23/USP30/ATP6V1B2/GABARAP/VPS28/TECPR1/PIK3C2B/TMEM41B/SNX5/CLN3/POLDIP2/PRKACA/RRAGC/GNAI3/PIK3CA/TRIM13/TSC1	47
BP	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	36/2159	215/18670	0.01434	0.2528	0.2342	BIRC3/TNFAIP8/DDX3X/CFLAR/TNFRSF10A/BID/CD27/AQP1/PMAIP1/CDKN2D/CASP4/RPS6KA3/TNFRSF10B/EGLN3/PDCD5/TNFSF15/MAP3K5/PLAUR/TNFSF10/CASP9/CD44/HSPE1/CAAP1/PAK2/JAK2/PRDX5/TP63/KHDC1/HSF1/ST20/APAF1/PPM1F/REST/BIRC2/POR/CASC2	36
BP	GO:0031398	positive regulation of protein ubiquitination	22/2159	117/18670	0.01438	0.2528	0.2342	BIRC3/NDFIP2/RASSF5/RNF20/CDK5RAP3/RIPK2/CAV1/PAXIP1/DCUN1D2/PELI1/PEF1/RNF111/SPHK1/UBE2N/CUL3/UBE2S/GOLGA2/SMAD7/BIRC2/MYCBP2/CRY1/NMI	22
BP	GO:0001657	ureteric bud development	19/2159	97/18670	0.01451	0.2528	0.2342	SIX1/BMP2/HOXA11/HES1/SLIT2/FGF1/CAT/ARG2/SOX8/SDC4/PGF/FGFR2/FOXC2/FAT4/FGFR1/SMAD7/AGTR2/PBX1/MAGED1	19
BP	GO:0014020	primary neural tube formation	19/2159	97/18670	0.01451	0.2528	0.2342	MKS1/ABL1/IFT172/FZD2/LIAS/LMO4/DEAF1/DVL3/FZD1/DVL2/SDC4/PHACTR4/LUZP1/VASP/APAF1/SEC24B/CC2D2A/PRKACA/TSC1	19
BP	GO:0021602	cranial nerve morphogenesis	8/2159	29/18670	0.01455	0.2528	0.2342	SIX1/ATP8B1/EGR2/HOXA1/EPHB2/HOXA3/TIFAB/ADARB1	8
BP	GO:0035666	TRIF-dependent toll-like receptor signaling pathway	8/2159	29/18670	0.01455	0.2528	0.2342	BIRC3/IKBKE/TANK/IRF3/CHUK/TRAF3/TLR4/BIRC2	8
BP	GO:0048545	response to steroid hormone	59/2159	385/18670	0.01458	0.2528	0.2342	FOSL1/FOS/ABHD2/PTGER2/CCND1/ATP2B1/DUSP1/CBFB/SREBF1/ZBTB7A/FOXP1/CFLAR/IDH1/ICAM1/PGRMC2/NR1D2/LBH/SLIT2/IL1RN/UFSP2/CAV1/GJB2/AQP1/DAXX/UCN/RELA/NR2F2/NKX2-2/PCK2/TGFB1I1/TXNIP/NR4A3/CASP9/ERRFI1/YAP1/HMGB2/JAK2/TRIM68/EIF4E/NR3C1/TP63/RB1/NR2F1/NOTCH1/FBXO32/AGTR2/THRA/NR4A2/GPAM/SMARCA4/REST/STRN3/SMYD3/VDR/NR2C2/PGR/NR3C2/DDX5/CRY1	59
BP	GO:0051101	regulation of DNA binding	23/2159	124/18670	0.01466	0.2535	0.2348	LIF/ZBTB7A/JUN/TRIM6/ZFP90/DDIT3/ITGA2/HES1/ZNF593/DOT1L/ID2/HEY2/HMGA2/PLAUR/HMGB2/JAK2/CPNE1/RB1/IFNG/ID3/ZNF462/HDAC2/IGF1	23
BP	GO:0030832	regulation of actin filament length	31/2159	180/18670	0.01506	0.2596	0.2405	VILL/ARHGAP28/ICAM1/ARF6/SLIT2/TMOD2/CXCL12/JMY/F2RL1/RHOBTB1/ARPC5L/ARPC5/GMFB/FMN2/PFN4/EVL/ARPC2/MYO1C/FCHSD2/RICTOR/PFN2/ARPC4/VASP/TMOD3/TRIOBP/PREX1/WDR1/WASL/RASA1/CDC42EP2/SPTA1	31
BP	GO:0001659	temperature homeostasis	30/2159	173/18670	0.01514	0.2599	0.2408	MAP2K6/PRKAB2/IL4R/EGR1/GADD45G/G0S2/DDIT3/GRB10/CAV1/TLE3/APPL2/DOCK7/EPAS1/TNFSF11/ABAT/FTO/ADAM17/ELOVL6/RBPJ/ACOT13/FOXC2/JAK2/RB1/OMA1/TLR4/PRDM16/NOTCH1/HSF1/THRA/HOXC10	30
BP	GO:0030099	myeloid cell differentiation	63/2159	416/18670	0.01516	0.2599	0.2408	FOS/RELB/ZBTB46/RBM15/CBFB/LIF/ZBTB7A/JUN/FOXP1/LDB1/NFE2/NRROS/EPHA2/JAG1/LYAR/CDKN1C/TRIB1/SLC25A38/HOXA7/F2RL1/HOXA5/NFE2L1/EPAS1/JMJD6/TNFSF11/BCL6/ACVR2A/ID2/KMT2E/IL11/RBPJ/TCTA/SFXN1/KAT6A/NR4A3/SNX10/TNRC6A/SH2B3/DNASE2/CASP9/FSTL3/HMGB2/JAK2/ASH2L/BATF3/PIP4K2A/UBASH3B/RB1/TLR4/IFNG/KLF13/CEBPA/TMOD3/THRA/PIK3CD/ROR2/JUNB/WDR1/JAGN1/CDKN2B/SLC11A2/CDK6/TOB2	63
BP	GO:0060606	tube closure	18/2159	91/18670	0.01548	0.2636	0.2442	MKS1/ABL1/IFT172/FZD2/LIAS/LMO4/DEAF1/DVL3/FZD1/DVL2/SDC4/PHACTR4/VASP/APAF1/SEC24B/CC2D2A/PRKACA/TSC1	18
BP	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	16/2159	78/18670	0.01558	0.2636	0.2442	BDKRB2/NUPR1/ZNF385B/JMY/PDK2/PMAIP1/HIPK1/CD44/RRN3/MUC1/SNW1/TP63/MYBBP1A/HNRNPK/DDX5/USP28	16
BP	GO:0046578	regulation of Ras protein signal transduction	39/2159	238/18670	0.01563	0.2636	0.2442	ABL1/SPRY2/MAP4K4/RASA2/ARHGEF9/SPRY4/ARF6/CCDC125/F2RL1/BCL6/ARHGDIA/SHC1/APOC3/KIF14/KCTD13/TIAM1/CUL3/PPP2CB/ECT2/JAK2/CDC42SE1/STMN3/NOTCH1/PDGFRB/EPHB2/STAMBP/PREX1/VAV3/FLOT1/STK19/MCF2L2/GPR20/MYO9B/CRKL/RGL2/RASA1/KCTD10/HRAS/IGF1	39
BP	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic	9/2159	35/18670	0.01569	0.2636	0.2442	DCP1A/EXOSC8/CNOT6/LSM6/POLR2G/LSM2/TTC37/EXOSC4/LSM4	9
BP	GO:0035909	aorta morphogenesis	9/2159	35/18670	0.01569	0.2636	0.2442	SIX1/HES1/JAG1/HEY2/RBPJ/NOTCH1/PDGFRB/SEC24B/TBX2	9
BP	GO:0009110	vitamin biosynthetic process	7/2159	24/18670	0.01602	0.2636	0.2442	PNPO/MMAB/NFKB1/AKR1A1/RFK/IFNG/VDR	7
BP	GO:0010288	response to lead ion	7/2159	24/18670	0.01602	0.2636	0.2442	CAT/CDK4/DNMT3A/PPP2CB/CPOX/QDPR/SLC6A1	7
BP	GO:0016054	organic acid catabolic process	44/2159	275/18670	0.01604	0.2636	0.2442	ABHD2/SDSL/GCDH/ETFB/ADO/MCCC1/ECI1/IVD/ARG2/ALDH5A1/BCKDHB/ACACB/GSTZ1/ALDH7A1/ECH1/DCXR/NUDT19/ENOSF1/SESN2/PCCB/ABAT/SLC9A1/BCAT2/PCK2/HYKK/EHHADH/MPST/AKR1A1/ABHD10/BLMH/HMGCL/CD44/MCEE/DBT/ALDH6A1/PECR/SLC25A17/QDPR/ACAA1/ABHD3/ACOX3/HOGA1/PCYOX1L/THNSL2	44
BP	GO:0046395	carboxylic acid catabolic process	44/2159	275/18670	0.01604	0.2636	0.2442	ABHD2/SDSL/GCDH/ETFB/ADO/MCCC1/ECI1/IVD/ARG2/ALDH5A1/BCKDHB/ACACB/GSTZ1/ALDH7A1/ECH1/DCXR/NUDT19/ENOSF1/SESN2/PCCB/ABAT/SLC9A1/BCAT2/PCK2/HYKK/EHHADH/MPST/AKR1A1/ABHD10/BLMH/HMGCL/CD44/MCEE/DBT/ALDH6A1/PECR/SLC25A17/QDPR/ACAA1/ABHD3/ACOX3/HOGA1/PCYOX1L/THNSL2	44
BP	GO:2000027	regulation of animal organ morphogenesis	41/2159	253/18670	0.01605	0.2636	0.2442	SIX1/BMP2/MKS1/ABL1/LIF/HOXA11/CFLAR/HES1/FZD2/FGF1/JAG1/PSME4/SMURF2/ETV5/SOX8/PSMC2/FGF7/DVL3/FZD1/DVL2/RBPJ/FGFR2/FOXC2/LIMS2/TUG1/TIAM1/MAGI2/PSMD4/RYK/AP2A2/TNFAIP3/FGFR1/NOTCH1/AGTR2/AP2M1/ROR2/SEC24B/VDR/TBX2/MAGED1/POR	41
BP	GO:0009063	cellular amino acid catabolic process	23/2159	125/18670	0.01606	0.2636	0.2442	SDSL/GCDH/ADO/MCCC1/IVD/ARG2/ALDH5A1/BCKDHB/GSTZ1/ALDH7A1/ENOSF1/ABAT/BCAT2/HYKK/MPST/BLMH/HMGCL/DBT/ALDH6A1/QDPR/HOGA1/PCYOX1L/THNSL2	23
BP	GO:0050702	interleukin-1 beta secretion	12/2159	53/18670	0.0161	0.2636	0.2442	FOXP1/RIPK2/ARG2/HK1/F2RL1/PANX1/SERPINB1/AIM2/TNFAIP3/TLR4/CPTP/TRIM16	12
BP	GO:0009119	ribonucleoside metabolic process	19/2159	98/18670	0.0161	0.2636	0.2442	HDDC3/MTAP/NT5E/GMPR2/NUDT18/CDADC1/IMPDH2/ADA/PNP/AMPD3/MFN1/RAB23/RHOQ/UCK1/ACPP/NME5/NME3/NME6/GNAI3	19
BP	GO:0072163	mesonephric epithelium development	19/2159	98/18670	0.0161	0.2636	0.2442	SIX1/BMP2/HOXA11/HES1/SLIT2/FGF1/CAT/ARG2/SOX8/SDC4/PGF/FGFR2/FOXC2/FAT4/FGFR1/SMAD7/AGTR2/PBX1/MAGED1	19
BP	GO:0072164	mesonephric tubule development	19/2159	98/18670	0.0161	0.2636	0.2442	SIX1/BMP2/HOXA11/HES1/SLIT2/FGF1/CAT/ARG2/SOX8/SDC4/PGF/FGFR2/FOXC2/FAT4/FGFR1/SMAD7/AGTR2/PBX1/MAGED1	19
BP	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	19/2159	98/18670	0.0161	0.2636	0.2442	BDKRB2/DDX3X/MCL1/CXCL12/ACKR3/BCL2A1/BID/PPIF/CDKN2D/PLAUR/CD44/RRN3/MUC1/CCAR2/BCL2L1/HSPB1/NDUFS3/NME5/BCL2L2	19
BP	GO:0097178	ruffle assembly	10/2159	41/18670	0.01621	0.2636	0.2442	ICAM1/ARF6/CAV1/SH3YL1/RHOG/SNX10/EVL/PFN2/PIP5K1A/HRAS	10
BP	GO:0035722	interleukin-12-mediated signaling pathway	11/2159	47/18670	0.0163	0.2636	0.2442	MTAP/GSTO1/TYK2/PLCB1/LMNB1/CNN2/SERPINB2/PAK2/JAK2/IFNG/IL12A	11
BP	GO:0061614	pri-miRNA transcription by RNA polymerase II	11/2159	47/18670	0.0163	0.2636	0.2442	FOSL1/FOS/BMP2/SREBF1/JUN/RELA/NR3C1/KLF5/SMARCA4/DDX5/TEAD1	11
BP	GO:0033135	regulation of peptidyl-serine phosphorylation	25/2159	139/18670	0.01638	0.2636	0.2442	BDKRB2/SPRY2/LIF/TRIM6/ERCC6/RIPK2/CAV1/PRKD1/DOCK7/UCN/FNIP2/PDE4D/IL11/GPD1L/CD44/RICTOR/PFN2/IRGM/INPP5F/IFNG/SMAD7/TERF2IP/PPM1F/SMYD3/PIK3CA	25
BP	GO:0035019	somatic stem cell population maintenance	15/2159	72/18670	0.01643	0.2636	0.2442	FOXP1/LDB1/HES1/LBH/BCL9L/POLR2I/VPS72/RBPJ/YAP1/TP63/POLR2G/PRDM16/PBX1/REST/LIG4	15
BP	GO:0002224	toll-like receptor signaling pathway	26/2159	146/18670	0.01646	0.2636	0.2442	BIRC3/IKBKE/TANK/TNIP1/NFKBIL1/RIPK2/CAV1/OTUD4/TRIL/IRF3/TAB3/RAB11FIP2/APPL2/PELI1/F2RL1/RPS6KA3/PJA2/CHUK/TRAF3/IRAK4/TNFAIP3/TLR4/LRRC19/IRAK2/FLOT1/BIRC2	26
BP	GO:0007519	skeletal muscle tissue development	28/2159	160/18670	0.01647	0.2636	0.2442	FOS/SIX1/MAFF/HIVEP3/EGR1/NUPR1/CFLAR/EGR2/NR1D2/CAV1/AKIRIN1/MYOM2/HOMER1/HLF/BCL9L/SOX8/NR2F2/MEF2D/EOMES/MYL6B/FOXN2/RB1/NOTCH1/KLF5/FLOT1/MYOZ2/ANKRD1/DDX5	28
BP	GO:0021915	neural tube development	28/2159	160/18670	0.01647	0.2636	0.2442	MKS1/ABL1/SALL2/IFT172/HES1/FZD2/LIAS/EPHA2/LMO4/PHGDH/ARL13B/DEAF1/DVL3/FZD1/DVL2/SDC4/PHACTR4/LUZP1/GSC/INTU/VASP/NOTCH1/IFT52/APAF1/SEC24B/CC2D2A/PRKACA/TSC1	28
BP	GO:0030203	glycosaminoglycan metabolic process	28/2159	160/18670	0.01647	0.2636	0.2442	ABCC5/CHST7/ST3GAL2/B4GALT3/GLCE/CHST2/SLC35D1/CHST14/ST3GAL1/B3GNT2/NFKB1/B4GALT5/SLC9A1/SDC4/UGDH/CD44/B4GALT6/HAS1/HS2ST1/CSGALNACT2/IMPAD1/PDGFRB/EXT1/CHST15/OMD/EXTL2/HS3ST3A1/CHST12	28
BP	GO:0001841	neural tube formation	20/2159	105/18670	0.01661	0.2639	0.2445	MKS1/ABL1/IFT172/FZD2/LIAS/LMO4/DEAF1/DVL3/FZD1/DVL2/SDC4/PHACTR4/LUZP1/VASP/IFT52/APAF1/SEC24B/CC2D2A/PRKACA/TSC1	20
BP	GO:0110053	regulation of actin filament organization	42/2159	261/18670	0.01672	0.2639	0.2445	ABL1/VILL/ARHGAP28/ICAM1/ARF6/RGS4/SLIT2/FHOD1/TMOD2/CXCL12/JMY/F2RL1/RHOBTB1/ARPC5L/SLC9A1/ARPC5/GMFB/FMN2/SDC4/FRMD7/PFN4/EVL/ARPC2/MYO1C/FCHSD2/RICTOR/PFN2/ARPC4/VASP/TMOD3/TRIOBP/RHOC/PREX1/WDR1/PPM1F/SH3PXD2B/WASL/RASA1/CDC42EP2/SPTA1/PHLDB2/TSC1	42
BP	GO:0014841	skeletal muscle satellite cell proliferation	5/2159	14/18670	0.0168	0.2639	0.2445	SIX1/CFLAR/AKIRIN1/JAK2/PAXBP1	5
BP	GO:0014857	regulation of skeletal muscle cell proliferation	5/2159	14/18670	0.0168	0.2639	0.2445	SIX1/CFLAR/AKIRIN1/JAK2/PAXBP1	5
BP	GO:0032688	negative regulation of interferon-beta production	5/2159	14/18670	0.0168	0.2639	0.2445	NLRX1/RELB/PPM1B/NLRC3/NMI	5
BP	GO:0045651	positive regulation of macrophage differentiation	5/2159	14/18670	0.0168	0.2639	0.2445	LIF/TRIB1/ID2/RB1/ROR2	5
BP	GO:0090178	regulation of establishment of planar polarity involved in neural tube closure	5/2159	14/18670	0.0168	0.2639	0.2445	FZD2/DVL3/FZD1/DVL2/SEC24B	5
BP	GO:0016075	rRNA catabolic process	6/2159	19/18670	0.01701	0.2657	0.2461	DIS3L/DROSHA/EXOSC8/PELO/EXOSC4/EXOSC10	6
BP	GO:0032700	negative regulation of interleukin-17 production	6/2159	19/18670	0.01701	0.2657	0.2461	ARG2/TLR4/IL27RA/IFNG/IL36RN/IL12A	6
BP	GO:0001763	morphogenesis of a branching structure	33/2159	196/18670	0.01709	0.2657	0.2461	SIX1/BMP2/MKS1/ABL1/SPRY2/RBM15/MMP14/HOXA11/SLIT2/FGF1/EPHA2/RDH10/FEM1B/HOXA5/ETV5/SOX8/FGF7/SOCS3/PGF/FGFR2/FOXC2/FAT4/YAP1/FGFR1/TP63/NOTCH1/AGTR2/PBX1/FOXF1/VDR/MAGED1/PGR/ERMN	33
BP	GO:0010389	regulation of G2/M transition of mitotic cell cycle	33/2159	196/18670	0.01709	0.2657	0.2461	CCND1/CCNB1/CDK5RAP3/CDK4/PSME4/PSMC2/VPS4A/ODF2/RAB11A/TUBB4B/HAUS5/KIF14/DONSON/HMGA2/CEP70/CEP57/MAPRE1/HAUS6/PSMD4/CSNK1E/NAE1/MTA3/RAD51C/PBX1/TUBA4A/CDC25C/RAD21/RAD17/CDC7/PRKACA/TOPBP1/SDCCAG8/HAUS3	33
BP	GO:0045665	negative regulation of neuron differentiation	37/2159	225/18670	0.01725	0.2666	0.247	MAP4K4/HES1/ARF6/SLIT2/JAG1/DENND5A/HES4/SOX8/ID2/DPYSL3/IFRD1/ARHGDIA/NKX2-2/PTK2/SEMA7A/GDI1/SNAPIN/CDK5R1/LINGO1/RYK/ASAP1/EIF4E/SRGAP2C/INPP5F/DNM3/NR2F1/NOTCH1/ID3/EPHB2/PBX1/REST/SEMA4G/HDAC2/EPHA4/ISL2/HOXA2/TSC1	37
BP	GO:0019362	pyridine nucleotide metabolic process	32/2159	189/18670	0.01728	0.2666	0.247	GPD2/ZBTB7A/NT5E/NUPR1/IDH1/RBKS/HK1/PRKAG1/DCXR/RAE1/RPIA/FOXK2/GPD1L/PKM/ADPGK/PARP16/PFKP/NUP35/IFNG/RNLS/SEH1L/FMO2/NUP98/MDH1B/HK2/NUP153/PFKM/NUDT17/DERA/PGLS/NAMPT/IGF1	32
BP	GO:0046496	nicotinamide nucleotide metabolic process	32/2159	189/18670	0.01728	0.2666	0.247	GPD2/ZBTB7A/NT5E/NUPR1/IDH1/RBKS/HK1/PRKAG1/DCXR/RAE1/RPIA/FOXK2/GPD1L/PKM/ADPGK/PARP16/PFKP/NUP35/IFNG/RNLS/SEH1L/FMO2/NUP98/MDH1B/HK2/NUP153/PFKM/NUDT17/DERA/PGLS/NAMPT/IGF1	32
BP	GO:0000086	G2/M transition of mitotic cell cycle	40/2159	247/18670	0.0174	0.2672	0.2476	CCND1/PPP2R2A/PHLDA1/CCNB1/CDK5RAP3/CDK4/PSME4/PSMC2/VPS4A/PLCB1/ODF2/RAB11A/TUBB4B/HAUS5/KIF14/AJUBA/DONSON/HMGA2/CEP70/CEP57/PPME1/MAPRE1/HAUS6/PSMD4/CSNK1E/NAE1/FBXL15/MTA3/RAD51C/PBX1/TUBA4A/CDC25C/RAD21/RAD17/CDKN2B/CDC7/PRKACA/TOPBP1/SDCCAG8/HAUS3	40
BP	GO:1901987	regulation of cell cycle phase transition	71/2159	480/18670	0.01741	0.2672	0.2476	DDX3X/CCND1/DBF4/DUSP1/CCNB1/ANAPC16/JADE1/CDK5RAP3/SLFN11/CDK4/CDKN1C/RFWD3/PSME4/BID/PAXIP1/CDKN1B/CDKN2D/PSMC2/ID2/ADAM17/KMT2E/APEX1/VPS4A/PLCB1/ODF2/PCBP4/RAB11A/TUBB4B/CNOT6L/RPA2/CDKN2C/HAUS5/KIF14/CNOT6/DONSON/HMGA2/CEP70/TFDP2/CEP57/NSMCE2/BABAM1/CUL3/MAPRE1/HAUS6/PSMD4/CSNK1E/MUC1/NAE1/GADD45A/MTA3/RAD51C/RB1/ATF5/TMOD3/CCND3/PBX1/E2F4/TUBA4A/CDC25C/RAD21/RAD17/CDKN2B/OVOL1/CDK6/PCID2/CDC7/PRKACA/TOPBP1/SDCCAG8/HAUS3/CDC27	71
BP	GO:0003151	outflow tract morphogenesis	16/2159	79/18670	0.0175	0.268	0.2483	SIX1/JUN/HES1/FZD2/JAG1/HEY2/FZD1/DVL2/RBPJ/FGFR2/FOXC2/NOTCH1/DHRS3/SEC24B/CRKL/TBX2	16
BP	GO:0018105	peptidyl-serine phosphorylation	47/2159	299/18670	0.01779	0.2711	0.2511	BDKRB2/HIPK3/IKBKE/SPRY2/ULK1/LIF/TRIM6/CCNB1/ERCC6/RIPK2/MKNK2/CAV1/TOP1/PRKD1/DOCK7/UCN/MAPKAPK5/PRKCZ/FNIP2/HIPK1/RPS6KA3/PDE4D/IL11/GPD1L/CHUK/HMGA2/PKN3/CD44/PRKCI/CDK5R1/RICTOR/PAK2/CSNK1E/PFN2/MARK3/IRGM/INPP5F/IFNG/SMAD7/TERF2IP/PPM1F/STK32A/SMYD3/CDC7/PRKACA/NLK/PIK3CA	47
BP	GO:0046330	positive regulation of JNK cascade	25/2159	140/18670	0.01782	0.2711	0.2511	GADD45G/ERCC6/RIPK2/IL1RN/CD27/F2RL1/TNFSF11/DAXX/PJA2/DVL3/PLCB1/MAP4K5/DVL2/ZNF622/MAP3K5/TIAM1/GADD45A/GADD45B/TLR4/IL36RN/ROR2/DUSP19/EPHA4/HRAS/IL36B	25
BP	GO:0032728	positive regulation of interferon-beta production	8/2159	30/18670	0.01788	0.2711	0.2511	DDX3X/RIPK2/IRF3/RNF135/HMGB2/TLR4/POLR3C/FLOT1	8
BP	GO:0061842	microtubule organizing center localization	8/2159	30/18670	0.01788	0.2711	0.2511	FHOD1/PARD3/ARPC5/GPSM2/KIF5B/MISP/NIN/BICD2	8
BP	GO:0043966	histone H3 acetylation	13/2159	60/18670	0.01797	0.2717	0.2517	LIF/LDB1/TAF5L/JADE1/ING4/JADE3/KAT6A/TAF6L/TADA2A/TAF12/TRIM16/SUPT7L/POLE3	13
BP	GO:0071559	response to transforming growth factor beta	41/2159	255/18670	0.01813	0.2734	0.2533	FOS/ZBTB7A/JUN/GDF5/CFLAR/CAV1/NRROS/LEMD3/CDKN1C/SMURF2/APPL2/YES1/PRKCZ/BCL9L/PARD3/ACVR2A/ADAM17/RNF111/PTK2/PDCD5/TGFB1I1/FUT8/ZYX/FGFR2/GIPC1/NREP/FURIN/NR3C1/SNW1/PRDM16/SMAD7/GLG1/APAF1/FYN/CRKL/CDKN2B/HDAC2/ANKRD1/NLK/EMILIN1/SMAD9	41
BP	GO:0005996	monosaccharide metabolic process	46/2159	292/18670	0.01822	0.2741	0.2539	GPD2/RBKS/ALDH5A1/GSTO1/HK1/ACACB/FGGY/GSTO2/PDK2/FUT4/NFE2L1/DCXR/SESN2/PMAIP1/PPP1R3E/RPIA/FPGT/FOXK2/PCK2/GALM/FUT8/SLC2A3/AKR1A1/PKM/COX11/ABHD10/ENPP1/ADPGK/SLC37A4/PFKP/SLC35B4/GDPGP1/OMA1/SLC23A2/DLAT/CHST15/SLC35A2/HK2/MAN2A1/PFKM/PMM1/CREM/NISCH/PIK3CA/CRY1/IGF1	46
BP	GO:0034404	nucleobase-containing small molecule biosynthetic process	37/2159	226/18670	0.0184	0.2761	0.2558	HDDC3/MTAP/ZBTB7A/NT5E/NUPR1/NUDT18/ACOT7/HK1/PRKAG1/IMPDH2/RAE1/FOXK2/ADA/PDE4D/PNP/AMPD3/PKM/ENPP1/ADPGK/PFKP/SMPDL3A/NUP35/DNPH1/IFNG/SEH1L/UCK1/NUP98/HK2/NME5/NME3/NUP153/NME6/PFKM/NUDT17/DERA/NUDT11/IGF1	37
BP	GO:0046434	organophosphate catabolic process	40/2159	248/18670	0.0185	0.277	0.2566	HDDC3/GPD2/ZBTB7A/NT5E/NUPR1/NUDT18/IDH1/ACOT7/SYNJ2/HK1/PRKAG1/RAE1/FOXK2/ADA/PDE4D/PNP/IMPA1/AMPD3/GPD1L/ENPP6/PKM/ENPP1/ADPGK/PFKP/SMPDL3A/INPP5F/NUP35/DNPH1/IFNG/SEH1L/INPP5B/NUP98/HK2/MTMR7/NUP153/PFKM/NUDT17/DERA/NUDT11/IGF1	40
BP	GO:0043392	negative regulation of DNA binding	12/2159	54/18670	0.01858	0.2775	0.2571	JUN/ZFP90/DDIT3/ZNF593/ID2/HEY2/HMGA2/JAK2/CPNE1/ID3/ZNF462/HDAC2	12
BP	GO:0050769	positive regulation of neurogenesis	70/2159	474/18670	0.01872	0.2787	0.2582	TNFRSF1B/BMP2/ZC4H2/LIF/MACF1/ADNP/GDF5/CFLAR/SCARF1/HES1/SLIT2/CLCF1/CXCL12/PRKD1/ZNF804A/RELA/ETV5/SOX8/BCL6/ID2/DPYSL3/ARHGDIA/MMD/DVL3/MAP2K1/NKX2-2/ZNF488/FZD1/NPTN/RAB11A/DVL2/SS18L1/BRINP1/TIAM1/MAGI2/BDNF/SEMA7A/GDI1/PRKCI/RRN3/TNFRSF12A/SRRT/CSNK1E/ECT2/TMEM30A/CPNE1/SRGAP2C/RGS2/FGFR1/DLG4/SNW1/IFNG/NOTCH1/IMPACT/EPHB2/STYXL1/SETX/ATF1/REST/CAPRIN1/FYN/MAN2A1/CRKL/ZFYVE27/HDAC2/ANKRD1/EPHA4/NIN/VEGFC/LIG4	70
BP	GO:0021953	central nervous system neuron differentiation	31/2159	183/18670	0.01875	0.2787	0.2582	ZC4H2/IFT172/EPHB3/LDB1/HES1/FBXO45/ZSWIM6/SLIT2/LMO4/NFE2L1/B4GALT5/NKX2-2/SATB2/FZD1/PTK2/FGFR2/EOMES/B4GALT6/RYK/CSNK1E/ATF5/EPHB2/NR4A2/CRKL/EPHA4/MYCBP2/ISL2/NIN/HERC1/HOXC10/ADARB1	31
BP	GO:0045740	positive regulation of DNA replication	9/2159	36/18670	0.01882	0.279	0.2585	DBF4/JUN/UCN/EREG/KCTD13/FGFR1/ATF1/CDC7/HRAS	9
BP	GO:0072080	nephron tubule development	18/2159	93/18670	0.01912	0.2828	0.262	SIX1/BMP2/LIF/HOXA11/HES1/FGF1/JAG1/WWTR1/SOX8/PGF/KLHL3/FAT4/YAP1/NOTCH1/CD24/AGTR2/PBX1/MAGED1	18
BP	GO:0030833	regulation of actin filament polymerization	28/2159	162/18670	0.01922	0.2833	0.2625	VILL/ARHGAP28/ICAM1/ARF6/SLIT2/TMOD2/JMY/RHOBTB1/ARPC5L/ARPC5/GMFB/FMN2/PFN4/EVL/ARPC2/MYO1C/FCHSD2/RICTOR/PFN2/ARPC4/VASP/TMOD3/TRIOBP/PREX1/WASL/RASA1/CDC42EP2/SPTA1	28
BP	GO:1901990	regulation of mitotic cell cycle phase transition	66/2159	444/18670	0.01925	0.2833	0.2625	DDX3X/CCND1/DUSP1/CCNB1/ANAPC16/JADE1/CDK5RAP3/SLFN11/CDK4/CDKN1C/RFWD3/PSME4/BID/CDKN1B/CDKN2D/PSMC2/ID2/ADAM17/KMT2E/APEX1/VPS4A/PLCB1/ODF2/PCBP4/RAB11A/TUBB4B/CNOT6L/RPA2/CDKN2C/HAUS5/KIF14/CNOT6/DONSON/HMGA2/CEP70/TFDP2/CEP57/NSMCE2/CUL3/MAPRE1/HAUS6/PSMD4/CSNK1E/MUC1/NAE1/GADD45A/MTA3/RAD51C/RB1/TMOD3/CCND3/PBX1/E2F4/TUBA4A/CDC25C/RAD21/RAD17/CDKN2B/CDK6/PCID2/CDC7/PRKACA/TOPBP1/SDCCAG8/HAUS3/CDC27	66
BP	GO:0043967	histone H4 acetylation	14/2159	67/18670	0.01954	0.2865	0.2654	JADE1/KANSL1L/PHF20/MSL1/ING4/JADE3/BEND3/KAT6A/KANSL1/MUC1/DMAP1/TRIM16/HAT1/MSL3	14
BP	GO:0097061	dendritic spine organization	16/2159	80/18670	0.0196	0.2865	0.2654	EPHB3/DOCK10/ZNF804A/HOMER1/CTNND2/SIPA1L1/TIAM1/CDK5R1/DLG4/DNM3/EPHB2/CAPRIN1/FYN/WASL/PDLIM5/EPHA4	16
BP	GO:0051403	stress-activated MAPK cascade	45/2159	286/18670	0.01973	0.2865	0.2654	BMP2/HIPK3/MAP4K4/DUSP1/GADD45G/ERCC6/RIPK2/IL1RN/TAB3/TRIB1/CD27/DUSP3/F2RL1/NFKB1/TNFSF11/DAXX/PJA2/MAP3K3/DVL3/MAP2K1/PLCB1/MAP4K5/SPHK1/DVL2/ZNF622/CHUK/MAP3K5/TIAM1/IRAK4/UBE2N/GADD45A/GADD45B/CCM2/TLR4/MAP4K3/IRAK2/MID1/IL36RN/ROR2/DTNBP1/CRKL/DUSP19/EPHA4/HRAS/IL36B	45
BP	GO:0009299	mRNA transcription	7/2159	25/18670	0.02008	0.2865	0.2654	HIPK3/SREBF1/ZBTB1/DDIT3/EREG/HSF1/DDX5	7
BP	GO:0032438	melanosome organization	7/2159	25/18670	0.02008	0.2865	0.2654	RAB32/TRAPPC6A/HPS4/SNAPIN/SHROOM2/DTNBP1/BLOC1S2	7
BP	GO:0051156	glucose 6-phosphate metabolic process	7/2159	25/18670	0.02008	0.2865	0.2654	RBKS/HK1/NFE2L1/RPIA/HK2/DERA/PGLS	7
BP	GO:1904385	cellular response to angiotensin	7/2159	25/18670	0.02008	0.2865	0.2654	CAV1/NFKB1/RELA/AGTRAP/ARID1B/AGTR2/HSF1	7
BP	GO:0044782	cilium organization	58/2159	384/18670	0.02011	0.2865	0.2654	MKS1/FAM161A/TTLL1/IFT172/EHD1/CCDC113/MNS1/B9D1/WWTR1/ARMC9/POC1B/DNAL1/ARL13B/IFT88/TMEM138/BBS10/C5orf30/NEK1/ODF2/RAB11A/TUBB4B/CBY1/HAUS5/TTC30B/SNX10/CEP70/CEP57/IFT46/UNC119B/MAPRE1/HAUS6/INTU/TMEM17/CSNK1E/ASAP1/IFT74/ARL6/CEP120/RPGR/RAB23/BBS2/NOTCH1/IFT52/DCDC2/E2F4/TTC30A/TMEM231/NME5/TUBA4A/GAS8/TMEM80/EXOC5/CC2D2A/RILPL2/PRKACA/CEP89/SDCCAG8/HAUS3	58
BP	GO:0030330	DNA damage response, signal transduction by p53 class mediator	20/2159	107/18670	0.02016	0.2865	0.2654	SPRED1/CCNB1/PAXIP1/CDKN1B/SESN2/PMAIP1/USP10/ING4/SPRED2/PCBP4/CNOT6L/CNOT6/TFDP2/CD44/MUC1/GADD45A/E2F4/CDC25C/ANKRD1/DDX5	20
BP	GO:0098781	ncRNA transcription	20/2159	107/18670	0.02016	0.2865	0.2654	ZNF143/ZC3H8/NABP1/POLR1E/POLR2I/SPIN1/INTS2/GTF2F2/SRRT/DDX11/POU2F2/SP1/ELL/POLR2G/POU2F1/SMARCA4/RPRD1A/TAF5/CCNT1/ICE2	20
BP	GO:0006644	phospholipid metabolic process	64/2159	430/18670	0.0204	0.2865	0.2654	SAMD8/ETNK1/LPCAT1/IDH1/MPPE1/SYNJ2/ALDH5A1/PIGC/PGAP2/ABHD4/PRKD1/MTMR12/DDHD1/PTPMT1/PIP5KL1/SERAC1/PLEKHA3/MTMR3/MFSD2A/SOCS5/SH3YL1/MVK/SGPP1/MTMR9/LCLAT1/PLCB1/SOCS3/PTK2/IMPA1/GPD1L/ENPP6/AJUBA/ACP6/SOCS7/CPNE1/SBF1/IMPAD1/INPP5F/SPTLC2/PIP4K2A/FAM126A/PIK3IP1/PIGB/PDGFRB/PIGV/INPP5B/NUS1/PIK3CD/GPAM/VAV3/PIK3C2B/PLA2G12A/MTMR7/LPCAT4/PGAP3/CDIPT/PIP5K1A/FDFT1/CLN3/ABHD3/MVD/RUFY1/GALR2/PIK3CA	64
BP	GO:0043414	macromolecule methylation	48/2159	309/18670	0.02044	0.2865	0.2654	FOS/TRMT6/RBM15/PCMT1/DIMT1/RNF20/ATF7IP/DNMT1/TET1/PAXIP1/DNMT3A/SETD1B/DOT1L/PRMT9/SETD4/PCMTD2/HEMK1/KMT2E/BCDIN3D/NSUN2/RRNAD1/BEND3/SETDB1/PHF1/ZNF304/TDRD1/ASH2L/KDM1B/TRMT10C/SNW1/GSPT1/PRDM16/HENMT1/PAXBP1/LCMT2/DMAP1/FAM98B/WDR5B/SUV39H2/SMYD3/TRMT1L/SETD3/TRMT2A/TRMT5/PIK3CA/ZC3H13/MTA2/BAZ2A	48
BP	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	13/2159	61/18670	0.02049	0.2865	0.2654	BIRC3/SPPL2A/F2RL1/HIPK1/CASP4/ADAM17/SPHK1/CHUK/TRAF1/TNFAIP3/CPNE1/PELI3/BIRC2	13
BP	GO:0008543	fibroblast growth factor receptor signaling pathway	21/2159	114/18670	0.0205	0.2865	0.2654	SPRY2/SPRED1/SPRY4/FGF1/FGF7/POLR2I/SPRED2/NPTN/FGFBP3/FGFR2/CEP57/SHISA2/FAT4/GTF2F2/KIF16B/DSTYK/FGFR1/POLR2G/SETX/FLRT1/CRKL	21
BP	GO:0006022	aminoglycan metabolic process	29/2159	170/18670	0.02056	0.2865	0.2654	ABCC5/CHST7/ST3GAL2/B4GALT3/GLCE/CHST2/B3GNT9/SLC35D1/CHST14/ST3GAL1/B3GNT2/NFKB1/B4GALT5/SLC9A1/SDC4/UGDH/CD44/B4GALT6/HAS1/HS2ST1/CSGALNACT2/IMPAD1/PDGFRB/EXT1/CHST15/OMD/EXTL2/HS3ST3A1/CHST12	29
BP	GO:0006081	cellular aldehyde metabolic process	15/2159	74/18670	0.02083	0.2865	0.2654	BMP2/IDH1/RBKS/PNPO/RDH10/ALDH7A1/RELA/RPIA/AKR1A1/CLCN2/REST/GRHPR/DERA/PGLS/HOGA1	15
BP	GO:0007015	actin filament organization	60/2159	400/18670	0.02088	0.2865	0.2654	ABL1/VILL/MSRB2/ARHGAP28/DIAPH2/ICAM1/DIAPH1/ARF6/RGS4/SLIT2/FHOD1/TMOD2/CXCL12/JMY/F2RL1/RHOBTB1/MYOM2/ARPC5L/DPYSL3/SLC9A1/ARPC5/GMFB/RHOG/FMN2/SDC4/FRMD7/ZYX/KCTD13/PFN4/ACTC1/EVL/ARPC2/MYO1C/PRKCI/CUL3/FCHSD2/RICTOR/JAK2/PFN2/ARPC4/VASP/TMOD3/RHOQ/TRIOBP/MSRB1/RHOC/ENAH/PREX1/WDR1/PPM1F/SHROOM2/CAP2/SH3PXD2B/WASL/RASA1/CDC42EP2/SPTA1/ERMN/PHLDB2/TSC1	60
BP	GO:1903322	positive regulation of protein modification by small protein conjugation or removal	24/2159	135/18670	0.02098	0.2865	0.2654	BIRC3/TANK/NDFIP2/TNIP1/RASSF5/RNF20/CDK5RAP3/RIPK2/CAV1/PAXIP1/DCUN1D2/PELI1/PEF1/RNF111/SPHK1/UBE2N/CUL3/UBE2S/GOLGA2/SMAD7/BIRC2/MYCBP2/CRY1/NMI	24
BP	GO:0034332	adherens junction organization	25/2159	142/18670	0.02099	0.2865	0.2654	ABL1/MAP4K4/SLK/MACF1/MMP14/LDB1/ITGA2/ARF6/PEAK1/DUSP3/HIPK1/BCAS3/SLC9A1/RASSF8/PTK2/SDC4/AJUBA/TRIP6/SMAD7/CADM1/RAB8B/PPM1F/PIP5K1A/PHLDB2/TSC1	25
BP	GO:0003149	membranous septum morphogenesis	4/2159	10/18670	0.02108	0.2865	0.2654	FZD2/ID2/FZD1/FGFR2	4
BP	GO:0006002	fructose 6-phosphate metabolic process	4/2159	10/18670	0.02108	0.2865	0.2654	GFPT2/NFE2L1/PFKP/PFKM	4
BP	GO:0007028	cytoplasm organization	4/2159	10/18670	0.02108	0.2865	0.2654	FOSL1/RRN3/KIF5B/ETV6	4
BP	GO:0010603	regulation of cytoplasmic mRNA processing body assembly	4/2159	10/18670	0.02108	0.2865	0.2654	PAN2/PAN3/CNOT6L/CNOT6	4
BP	GO:0015937	coenzyme A biosynthetic process	4/2159	10/18670	0.02108	0.2865	0.2654	ACOT7/PPCDC/PANK1/PPCS	4
BP	GO:0032926	negative regulation of activin receptor signaling pathway	4/2159	10/18670	0.02108	0.2865	0.2654	LEMD3/FST/MAGI2/FSTL3	4
BP	GO:0033690	positive regulation of osteoblast proliferation	4/2159	10/18670	0.02108	0.2865	0.2654	BMP2/ABL1/SOX8/TMEM119	4
BP	GO:0034058	endosomal vesicle fusion	4/2159	10/18670	0.02108	0.2865	0.2654	VPS11/VPS4A/SPHK1/VPS8	4
BP	GO:0045713	low-density lipoprotein particle receptor biosynthetic process	4/2159	10/18670	0.02108	0.2865	0.2654	ITGB3/SEC24A/FURIN/HNRNPK	4
BP	GO:0045876	positive regulation of sister chromatid cohesion	4/2159	10/18670	0.02108	0.2865	0.2654	FEN1/NSMCE2/DDX11/RAD21	4
BP	GO:0045945	positive regulation of transcription by RNA polymerase III	4/2159	10/18670	0.02108	0.2865	0.2654	ZC3H8/ELL/CEBPA/ICE2	4
BP	GO:0052646	alditol phosphate metabolic process	4/2159	10/18670	0.02108	0.2865	0.2654	GPD2/GPD1L/ACP6/GPAM	4
BP	GO:0090030	regulation of steroid hormone biosynthetic process	4/2159	10/18670	0.02108	0.2865	0.2654	BMP2/CLCN2/REST/POR	4
BP	GO:0090309	positive regulation of methylation-dependent chromatin silencing	4/2159	10/18670	0.02108	0.2865	0.2654	ATF7IP/DNMT1/SETDB1/ZNF304	4
BP	GO:2000628	regulation of miRNA metabolic process	4/2159	10/18670	0.02108	0.2865	0.2654	NFKB1/RELA/DROSHA/HRAS	4
BP	GO:0044728	DNA methylation or demethylation	18/2159	94/18670	0.02118	0.2865	0.2654	FOS/ATF7IP/DNMT1/OTUD4/TET1/DNMT3A/ALKBH3/FTO/HEMK1/KMT2E/APEX1/BEND3/TDRD1/KDM1B/DMAP1/PIK3CA/MTA2/BAZ2A	18
BP	GO:0051289	protein homotetramerization	18/2159	94/18670	0.02118	0.2865	0.2654	CAT/ALDH5A1/ACACB/APPL2/DCXR/IMPDH2/CBY1/PCBD2/ACOT13/PKM/EVL/PFKP/GOLGA2/TP63/TRPA1/VASP/ACPP/PFKM	18
BP	GO:0044319	wound healing, spreading of cells	8/2159	31/18670	0.02173	0.2919	0.2704	TOR1A/ADAM17/HBEGF/AJUBA/CD44/PDPN/RHOC/PHLDB2	8
BP	GO:0090505	epiboly involved in wound healing	8/2159	31/18670	0.02173	0.2919	0.2704	TOR1A/ADAM17/HBEGF/AJUBA/CD44/PDPN/RHOC/PHLDB2	8
BP	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	8/2159	31/18670	0.02173	0.2919	0.2704	CXCL12/ACKR3/BID/CDKN2D/CD44/MUC1/CCAR2/BCL2L1	8
BP	GO:0022406	membrane docking	30/2159	178/18670	0.02187	0.292	0.2705	MKS1/ICAM1/VAPB/STX6/B9D1/RALB/STX1A/VPS11/ODF2/RAB11A/TUBB4B/HAUS5/CEP70/CEP57/MAPRE1/HAUS6/CSNK1E/SNPH/SYTL2/PEX16/RAB8B/TUBA4A/EXOC5/CC2D2A/PRKACA/STXBP1/CEP89/SDCCAG8/HAUS3/VPS45	30
BP	GO:1902930	regulation of alcohol biosynthetic process	16/2159	81/18670	0.02189	0.292	0.2705	BMP2/SREBF1/FGF1/ACACB/NFKB1/MVK/ELOVL6/SP1/IFNG/CLCN2/GPAM/REST/VDR/FDFT1/POR/MVD	16
BP	GO:0042474	middle ear morphogenesis	6/2159	20/18670	0.02197	0.292	0.2705	SIX1/OSR2/GSC/TSHZ1/FGFR1/HOXA2	6
BP	GO:0060602	branch elongation of an epithelium	6/2159	20/18670	0.02197	0.292	0.2705	SIX1/SPRY2/FGF1/RDH10/FGFR2/YAP1	6
BP	GO:0072234	metanephric nephron tubule development	6/2159	20/18670	0.02197	0.292	0.2705	LIF/HES1/WWTR1/SOX8/FAT4/YAP1	6
BP	GO:0071349	cellular response to interleukin-12	11/2159	49/18670	0.02202	0.292	0.2705	MTAP/GSTO1/TYK2/PLCB1/LMNB1/CNN2/SERPINB2/PAK2/JAK2/IFNG/IL12A	11
BP	GO:0071156	regulation of cell cycle arrest	20/2159	108/18670	0.02214	0.292	0.2705	CCND1/CCNB1/CRLF3/CDK4/CDKN1B/ID2/PCBP4/CNOT6L/CNOT6/HMGA2/TFDP2/CDK5R1/MUC1/GADD45A/ZNF268/MYBBP1A/E2F4/SDE2/CDC25C/PRKACA	20
BP	GO:0045017	glycerolipid biosynthetic process	40/2159	251/18670	0.02214	0.292	0.2705	SREBF1/ETNK1/LPCAT1/MPPE1/SYNJ2/PIGC/PGAP2/MTMR12/DDHD1/PTPMT1/PLEKHA3/MTMR3/MFSD2A/SH3YL1/MTMR9/PCK2/LCLAT1/IMPA1/GPD1L/AJUBA/ACP6/CPNE1/SBF1/INPP5F/PIP4K2A/PIGB/PIGV/PIK3CD/GPAM/PIK3C2B/PLA2G12A/MTMR7/LPCAT4/PGAP3/CDIPT/PIP5K1A/ABHD3/RUFY1/ACSL4/PIK3CA	40
BP	GO:0051090	regulation of DNA-binding transcription factor activity	64/2159	432/18670	0.0223	0.292	0.2705	FOSL1/FOS/NFKBIE/ZBTB7A/JUN/NUPR1/NFKBIL1/CFLAR/DDIT3/NFKB2/ICAM1/CDK5RAP3/FZD2/RIPK2/CAT/CAV1/TAB3/NDP/JMY/TRIB1/PAXIP1/PRKD1/PELI1/NFKB1/TCF7L2/TNFSF11/RELA/PRKCZ/RHEBL1/ID2/NKX2-2/FZD1/SPHK1/DVL2/CHUK/NLRC3/EOMES/TRAF1/TP53BP1/TRAF3/ENPP1/IRAK4/UBE2N/PRKCI/AIM2/JAK2/TNFAIP3/MID2/RB1/TLR4/IRAK2/TAF12/SMAD7/ID3/MTDH/TERF2IP/SMARCA4/FLOT1/HDAC2/PPRC1/NHLH2/LRRFIP1/DHX33/TRIM13	64
BP	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	9/2159	37/18670	0.0224	0.292	0.2705	AGO2/PAN2/PAN3/MLH1/CNOT6L/PARN/CNOT6/TNRC6A/POLR2G	9
BP	GO:0048644	muscle organ morphogenesis	17/2159	88/18670	0.02273	0.292	0.2705	BMP2/LIF/FZD2/PTCD2/UBE4B/MYOM2/HEY2/FZD1/RBPJ/FGFR2/FOXC2/ACTC1/GSC/SMAD7/NOTCH1/ANKRD1/ADARB1	17
BP	GO:0106027	neuron projection organization	17/2159	88/18670	0.02273	0.292	0.2705	EPHB3/DOCK10/ZNF804A/HOMER1/CTNND2/SIPA1L1/TIAM1/CDK5R1/DLG4/DNM3/MAP1A/EPHB2/CAPRIN1/FYN/WASL/PDLIM5/EPHA4	17
BP	GO:0001829	trophectodermal cell differentiation	5/2159	15/18670	0.02284	0.292	0.2705	ADA/EOMES/CUL3/BYSL/JUNB	5
BP	GO:0002467	germinal center formation	5/2159	15/18670	0.02284	0.292	0.2705	NFKB2/BCL6/ADAM17/ADA/TNFAIP3	5
BP	GO:0014856	skeletal muscle cell proliferation	5/2159	15/18670	0.02284	0.292	0.2705	SIX1/CFLAR/AKIRIN1/JAK2/PAXBP1	5
BP	GO:0032988	ribonucleoprotein complex disassembly	5/2159	15/18670	0.02284	0.292	0.2705	MTIF2/KIF5B/PELO/MRRF/TFIP11	5
BP	GO:0042762	regulation of sulfur metabolic process	5/2159	15/18670	0.02284	0.292	0.2705	PDP2/GSTZ1/PDK2/SP1/PDP1	5
BP	GO:0043101	purine-containing compound salvage	5/2159	15/18670	0.02284	0.292	0.2705	MTAP/GMPR2/ADA/PNP/AMPD3	5
BP	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	5/2159	15/18670	0.02284	0.292	0.2705	SPRED1/PMAIP1/SPRED2/ANKRD1/DDX5	5
BP	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	5/2159	15/18670	0.02284	0.292	0.2705	MAP2K6/JAK2/TLR4/IFNG/NAMPT	5
BP	GO:0072148	epithelial cell fate commitment	5/2159	15/18670	0.02284	0.292	0.2705	NR2F2/NKX2-2/RBPJ/PDPN/NOTCH1	5
BP	GO:0072160	nephron tubule epithelial cell differentiation	5/2159	15/18670	0.02284	0.292	0.2705	LIF/WWTR1/FAT4/YAP1/CD24	5
BP	GO:0090177	establishment of planar polarity involved in neural tube closure	5/2159	15/18670	0.02284	0.292	0.2705	FZD2/DVL3/FZD1/DVL2/SEC24B	5
BP	GO:0043087	regulation of GTPase activity	70/2159	479/18670	0.02315	0.295	0.2733	SPRY2/MAP4K4/ARHGAP19/RASA2/JUN/EPHB3/ARHGAP28/ICAM1/SMAP2/CCDC125/RGS4/SYDE2/SLIT2/CCL7/RP2/EPHA2/RAB11FIP2/F2RL1/DOCK10/DOCK7/TBC1D19/TRAPPC6A/STARD8/BCL6/BCAS3/RABGAP1/RGS17/ARHGDIA/DVL3/AGAP1/SIPA1L1/SIPA1L3/PLCB1/RHOG/LRCH1/PTK2/DVL2/ARHGAP22/AJUBA/AGFG1/TIAM1/ACAP2/GDI1/ERRFI1/RAPGEF6/RICTOR/ECT2/ASAP1/SRGAP1/SBF1/RGS2/CDC42SE1/STMN3/SIPA1L2/PICALM/PREX1/VAV3/EVI5/ELMOD3/MYO9B/RGS16/PIP5K1A/CRKL/EPHA4/AGAP6/RASA1/CDC42EP2/HRAS/TSC1/SIPA1	70
BP	GO:0002753	cytoplasmic pattern recognition receptor signaling pathway	13/2159	62/18670	0.02327	0.295	0.2733	BIRC3/MAP2K6/NLRX1/RIPK2/IRF3/TAB3/RELA/UBE2N/TNFAIP3/IRGM/TLR4/IRAK2/BIRC2	13
BP	GO:0032922	circadian regulation of gene expression	13/2159	62/18670	0.02327	0.295	0.2733	CIART/RELB/EGR1/PER3/TOP1/ID2/CSNK1E/MYBBP1A/HDAC2/MAGED1/MYCBP2/CRY1/NAMPT	13
BP	GO:0007517	muscle organ development	61/2159	410/18670	0.02328	0.295	0.2733	FOS/EGR3/SIX1/BMP2/MAFF/SGCD/HIVEP3/LIF/EGR1/NUPR1/CHD2/BTBD1/CCNB1/CFLAR/EGR2/FZD2/PARP2/RGS4/NR1D2/PTCD2/CAV1/UBE4B/AKIRIN1/EID2B/MYOM2/HOMER1/HLF/BCL9L/SOX8/NR2F2/SMTN/HEY2/FZD1/HBEGF/MEF2D/RBPJ/FGFR2/EOMES/FOXC2/ACTC1/MYL6B/GSC/ETV1/YAP1/RGS2/FGFR1/FOXN2/RB1/SMAD7/NOTCH1/ID3/KLF5/PAXBP1/FLOT1/MYOZ2/TIFAB/ANKRD1/TBX2/DDX5/ADARB1/IGF1	61
BP	GO:0061326	renal tubule development	18/2159	95/18670	0.02339	0.2959	0.2741	SIX1/BMP2/LIF/HOXA11/HES1/FGF1/JAG1/WWTR1/SOX8/PGF/KLHL3/FAT4/YAP1/NOTCH1/CD24/AGTR2/PBX1/MAGED1	18
BP	GO:0030324	lung development	29/2159	172/18670	0.02375	0.2992	0.2772	SPRY2/SREBF1/LIF/MMP14/HES1/FGF1/RDH10/HOXA5/EPAS1/JMJD6/FGF7/MAP2K1/ADA/RBPJ/FGFR2/ERRFI1/FSTL3/YAP1/EIF4E/FGFR1/PDPN/CEBPA/NOTCH1/PDGFRB/THRA/MAN2A1/SEC24B/FOXF1/PGR	29
BP	GO:0032874	positive regulation of stress-activated MAPK cascade	29/2159	172/18670	0.02375	0.2992	0.2772	BMP2/GADD45G/ERCC6/RIPK2/IL1RN/CD27/F2RL1/TNFSF11/DAXX/PJA2/MAP3K3/DVL3/PLCB1/MAP4K5/SPHK1/DVL2/ZNF622/MAP3K5/TIAM1/GADD45A/GADD45B/TLR4/MID1/IL36RN/ROR2/DUSP19/EPHA4/HRAS/IL36B	29
BP	GO:2001242	regulation of intrinsic apoptotic signaling pathway	28/2159	165/18670	0.02402	0.3019	0.2797	BDKRB2/DDX3X/NUPR1/DDIT3/MCL1/CAV1/PLEKHF1/CXCL12/ACKR3/BCL2A1/BID/PTPMT1/PMAIP1/PPIF/CDKN2D/PLAUR/CD44/RRN3/MUC1/CCAR2/BCL2L1/HSPB1/NDUFS3/RAD9A/STYXL1/NME5/HNRNPK/BCL2L2	28
BP	GO:0072009	nephron epithelium development	20/2159	109/18670	0.02426	0.3043	0.2819	SIX1/BMP2/LIF/HOXA11/HES1/FGF1/JAG1/WWTR1/SOX8/PGF/KLHL3/FOXC2/MAGI2/FAT4/YAP1/NOTCH1/CD24/AGTR2/PBX1/MAGED1	20
BP	GO:0071158	positive regulation of cell cycle arrest	16/2159	82/18670	0.02437	0.3047	0.2823	CCNB1/CRLF3/CDKN1B/ID2/PCBP4/CNOT6L/CNOT6/HMGA2/TFDP2/CDK5R1/MUC1/GADD45A/MYBBP1A/E2F4/CDC25C/PRKACA	16
BP	GO:0090183	regulation of kidney development	12/2159	56/18670	0.02439	0.3047	0.2823	SIX1/LIF/EGR1/CFLAR/WWTR1/SOX8/FAT4/YAP1/CD24/PDGFRB/AGTR2/MAGED1	12
BP	GO:0008033	tRNA processing	23/2159	130/18670	0.0247	0.3079	0.2852	ELP4/PUS10/TRMT6/TP53RK/OSGEPL1/SEPHS2/BCDIN3D/NSUN2/ELAC1/POLR3K/LSM6/TRMT10C/TYW1/LCMT2/FAM98B/RPUSD4/TRMT1L/SEPHS1/OSGEP/QTRT1/TRMT5/TRMU/DUS1L	23
BP	GO:0048753	pigment granule organization	7/2159	26/18670	0.02481	0.308	0.2854	RAB32/TRAPPC6A/HPS4/SNAPIN/SHROOM2/DTNBP1/BLOC1S2	7
BP	GO:1903203	regulation of oxidative stress-induced neuron death	7/2159	26/18670	0.02481	0.308	0.2854	MCL1/FZD1/NR4A3/TLR4/LANCL1/REST/TSC1	7
BP	GO:0070126	mitochondrial translational termination	17/2159	89/18670	0.02517	0.3114	0.2885	MRPL40/MRPS6/OXA1L/MRPS18C/MRPL17/MRPS14/MRPS18A/MTRF1L/MRPL11/MRPL10/MRPS16/MRPL24/MRPS33/MRPS31/MRRF/MRPS36/MRPL2	17
BP	GO:0072522	purine-containing compound biosynthetic process	48/2159	313/18670	0.02519	0.3114	0.2885	MTAP/ZBTB7A/NT5E/NUPR1/GMPR2/GCDH/ACOT7/PDP2/HK1/ACACB/GSTZ1/PRKAG1/PDK2/PRPS1/PRPSAP2/IMPDH2/RAE1/PPCDC/ELOVL7/FOXK2/HSD17B8/ADA/PANK1/ELOVL6/PNP/AMPD3/PKM/ADPGK/PRPS2/PFKP/NUP35/SLC26A1/IFNG/SEH1L/DLAT/NUP98/HK2/NME5/NME3/NUP153/NME6/PFKM/ELOVL4/PDP1/ACSL4/NPR2/IGF1/PPCS	48
BP	GO:0033059	cellular pigmentation	11/2159	50/18670	0.02537	0.3125	0.2896	RAB32/TRAPPC6A/RAB11A/HPS4/SNAPIN/ARL6/BBS2/MYO5A/SHROOM2/DTNBP1/BLOC1S2	11
BP	GO:0048872	homeostasis of number of cells	39/2159	246/18670	0.02545	0.3125	0.2896	TSC22D3/ABL1/ZBTB7A/LDB1/VPS54/ZC3H8/LYAR/SLC25A38/DOCK10/RPS24/HOXA5/NFE2L1/EPAS1/JMJD6/PMAIP1/BCL6/POLB/ACVR2A/ID2/ADAM17/KMT2E/ADA/AMPD3/SFXN1/SH2B3/DNASE2/RRN3/HMGB2/JAK2/TNFAIP3/RB1/KLF13/NOTCH1/TMOD3/THRA/PIK3CD/SLC11A2/CDK6/SPTA1	39
BP	GO:0003002	regionalization	53/2159	351/18670	0.02546	0.3125	0.2896	MEOX1/SIX1/BMP2/MKS1/TBX18/HOXA11/IFT172/HOXA10/LDB1/HOXD8/MNS1/DDIT3/HES1/EGR2/FGF1/HOXA7/HOXA5/OTX1/ARL13B/MESP2/HES4/HOXA6/HIPK1/ACVR2A/NR2F2/HEY2/NKX2-2/SCMH1/DVL2/RBPJ/FGFR2/EOMES/FOXC2/GSC/EMX2/INTU/GREM2/FBXL15/TSHZ1/FGFR1/TP63/NOTCH1/IFT52/ROR2/PBX1/HOXA3/TIFAB/CRKL/FOXF1/HOXA2/PRKACA/HOXD4/HOXC10	53
BP	GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	29/2159	173/18670	0.02549	0.3125	0.2896	BMP2/GADD45G/ERCC6/RIPK2/IL1RN/CD27/F2RL1/TNFSF11/DAXX/PJA2/MAP3K3/DVL3/PLCB1/MAP4K5/SPHK1/DVL2/ZNF622/MAP3K5/TIAM1/GADD45A/GADD45B/TLR4/MID1/IL36RN/ROR2/DUSP19/EPHA4/HRAS/IL36B	29
BP	GO:0019674	NAD metabolic process	15/2159	76/18670	0.02608	0.3132	0.2902	GPD2/NT5E/HK1/FOXK2/GPD1L/PKM/ADPGK/PARP16/PFKP/RNLS/MDH1B/HK2/PFKM/NUDT17/NAMPT	15
BP	GO:0060411	cardiac septum morphogenesis	15/2159	76/18670	0.02608	0.3132	0.2902	MKS1/RBM15/HES1/FZD2/SLIT2/JAG1/ID2/HEY2/FZD1/RBPJ/FGFR2/SMAD7/NOTCH1/DHRS3/TBX2	15
BP	GO:0006195	purine nucleotide catabolic process	10/2159	44/18670	0.0261	0.3132	0.2902	HDDC3/NT5E/NUDT18/ACOT7/ADA/PDE4D/PNP/AMPD3/DNPH1/NUDT11	10
BP	GO:0070897	transcription preinitiation complex assembly	10/2159	44/18670	0.0261	0.3132	0.2902	ATF7IP/BRF2/POLR1E/PSMC2/RRN3/TAF6L/TAF12/THRA/SMARCA4/BAZ2A	10
BP	GO:0090311	regulation of protein deacetylation	10/2159	44/18670	0.0261	0.3132	0.2902	SPRED1/SREBF1/PRKD1/UCN/BCL6/SPRED2/C6orf89/CCAR2/IFNG/AKAP8	10
BP	GO:0003176	aortic valve development	8/2159	32/18670	0.02612	0.3132	0.2902	TNFRSF1B/SLIT2/JAG1/HEY2/RBPJ/RB1/NOTCH1/EMILIN1	8
BP	GO:0006739	NADP metabolic process	8/2159	32/18670	0.02612	0.3132	0.2902	IDH1/RBKS/DCXR/RPIA/FMO2/NUDT17/DERA/PGLS	8
BP	GO:0035510	DNA dealkylation	8/2159	32/18670	0.02612	0.3132	0.2902	OTUD4/TET1/ALKBH3/ALKBH5/ASCC1/FTO/APEX1/MPG	8
BP	GO:0090504	epiboly	8/2159	32/18670	0.02612	0.3132	0.2902	TOR1A/ADAM17/HBEGF/AJUBA/CD44/PDPN/RHOC/PHLDB2	8
BP	GO:1900745	positive regulation of p38MAPK cascade	8/2159	32/18670	0.02612	0.3132	0.2902	BMP2/GADD45G/PJA2/MAP3K3/SPHK1/MAP3K5/GADD45A/GADD45B	8
BP	GO:1901976	regulation of cell cycle checkpoint	8/2159	32/18670	0.02612	0.3132	0.2902	DUSP1/CCNB1/RFWD3/FEM1B/RPA2/CCAR2/PCID2/CRY1	8
BP	GO:0031571	mitotic G1 DNA damage checkpoint	13/2159	63/18670	0.02632	0.3138	0.2907	CCND1/CCNB1/RFWD3/CDKN1B/PCBP4/CNOT6L/RPA2/CNOT6/TFDP2/MUC1/GADD45A/E2F4/CDC25C	13
BP	GO:0044819	mitotic G1/S transition checkpoint	13/2159	63/18670	0.02632	0.3138	0.2907	CCND1/CCNB1/RFWD3/CDKN1B/PCBP4/CNOT6L/RPA2/CNOT6/TFDP2/MUC1/GADD45A/E2F4/CDC25C	13
BP	GO:1904377	positive regulation of protein localization to cell periphery	13/2159	63/18670	0.02632	0.3138	0.2907	ARF6/EPHA2/RAB11FIP2/RHOG/STAC/RAB11A/GPSM2/PRKCI/KIF5B/IFNG/NKD2/EPHB2/EPB41L2	13
BP	GO:0006040	amino sugar metabolic process	9/2159	38/18670	0.02643	0.3138	0.2907	UAP1/CHST7/CHST2/GFPT2/ST3GAL1/GNE/UAP1L1/GNPNAT1/EXTL2	9
BP	GO:0006084	acetyl-CoA metabolic process	9/2159	38/18670	0.02643	0.3138	0.2907	PDP2/ACACB/GSTZ1/PDK2/MVK/DLAT/MVD/PDP1/PPCS	9
BP	GO:1901292	nucleoside phosphate catabolic process	31/2159	188/18670	0.02647	0.3138	0.2907	HDDC3/ZBTB7A/NT5E/NUPR1/NUDT18/ACOT7/HK1/PRKAG1/RAE1/FOXK2/ADA/PDE4D/PNP/AMPD3/PKM/ENPP1/ADPGK/PFKP/SMPDL3A/NUP35/DNPH1/IFNG/SEH1L/NUP98/HK2/NUP153/PFKM/NUDT17/DERA/NUDT11/IGF1	31
BP	GO:0043434	response to peptide hormone	64/2159	436/18670	0.02654	0.3139	0.2908	ATP2B1/GHR/SREBF1/EGR1/ATP6V1E2/CFLAR/ICAM1/EGR2/GRB10/CAT/CAV1/CDK4/CXCL12/GJB2/PDK2/APPL2/CDKN1B/NFKB1/SESN2/RELA/PRKCZ/SESN3/SLC9A1/APEX1/C2CD5/GKAP1/PCK2/SHC1/SOCS3/EREG/PTK2/CHUK/FOXC2/PKM/NR4A3/AGTRAP/TNFSF10/MYO1C/ENPP1/ERRFI1/PRKCI/PRKAR1A/ARID1B/JAK2/SP1/AGTR2/ATP6V1B2/RHOQ/HSF1/CCND3/RAB8B/NR4A2/CPEB1/MYO5A/IGFBP1/QDPR/FYN/TRIM16/POR/PRKAR2A/PRKACA/PIK3CA/TSC1/CRY1	64
BP	GO:0001736	establishment of planar polarity	22/2159	124/18670	0.0268	0.3152	0.292	MKS1/ABL1/FZD2/PSME4/SMURF2/PSMC2/DVL3/FZD1/DVL2/TIAM1/MAGI2/INTU/PSMD4/RYK/AP2A2/ASTN2/TP63/AP2M1/ROR2/WDR1/SEC24B/EXOC5	22
BP	GO:0001838	embryonic epithelial tube formation	22/2159	124/18670	0.0268	0.3152	0.292	SIX1/MKS1/ABL1/IFT172/FZD2/LIAS/LMO4/SOX8/DEAF1/DVL3/FZD1/DVL2/SDC4/PHACTR4/LUZP1/VASP/IFT52/APAF1/SEC24B/CC2D2A/PRKACA/TSC1	22
BP	GO:0007164	establishment of tissue polarity	22/2159	124/18670	0.0268	0.3152	0.292	MKS1/ABL1/FZD2/PSME4/SMURF2/PSMC2/DVL3/FZD1/DVL2/TIAM1/MAGI2/INTU/PSMD4/RYK/AP2A2/ASTN2/TP63/AP2M1/ROR2/WDR1/SEC24B/EXOC5	22
BP	GO:0042509	regulation of tyrosine phosphorylation of STAT protein	16/2159	83/18670	0.02706	0.3176	0.2942	GHR/LIF/HES1/CAV1/CLCF1/SOCS3/SH2B3/JAK2/IL22RA2/INPP5F/IFNG/HSF1/IL12A/FYN/HDAC2/IGF1	16
BP	GO:0051310	metaphase plate congression	12/2159	57/18670	0.02775	0.3229	0.2991	CCNB1/CHMP7/GEM/VPS4A/MLH1/RAB11A/KIF14/CUL3/SEH1L/MIS12/KIF2B/TTL	12
BP	GO:0046486	glycerolipid metabolic process	61/2159	414/18670	0.02779	0.3229	0.2991	ABHD2/SREBF1/ETNK1/LPCAT1/MPPE1/SYNJ2/CAT/CAV1/ALDH5A1/PIGC/PGAP2/ABHD4/MTMR12/DDHD1/PTPMT1/PIP5KL1/SERAC1/PLEKHA3/MTMR3/MFSD2A/SOCS5/SH3YL1/MTMR9/PCK2/LCLAT1/PLCB1/SOCS3/APOC3/PNPLA4/IMPA1/GPD1L/ENPP6/TBL1XR1/AJUBA/ACP6/SOCS7/CPNE1/SBF1/IMPAD1/INPP5F/PIP4K2A/FAM126A/PIGB/PDGFRB/DAGLB/PIGV/INPP5B/PIK3CD/GPAM/PIK3C2B/PLA2G12A/MTMR7/LPCAT4/PGAP3/CDIPT/PIP5K1A/ABHD3/RUFY1/GALR2/ACSL4/PIK3CA	61
BP	GO:0001656	metanephros development	17/2159	90/18670	0.0278	0.3229	0.2991	SIX1/LIF/OSR2/EGR1/HOXA11/HES1/WWTR1/RDH10/SOX8/ID2/FOXC2/FAT4/YAP1/ID3/PDGFRB/AGTR2/FRAS1	17
BP	GO:0007409	axonogenesis	68/2159	468/18670	0.02781	0.3229	0.2991	ABL1/ULK1/MAP1S/MACF1/EPHB3/ADNP/PALLD/NEXN/EGR2/FBXO45/ZSWIM6/GRB10/SLIT2/EPHA2/CXCL12/B3GNT2/DOCK7/B4GALT5/WDR36/PARD3/IFRD1/ARHGDIA/MAP2K1/SIPA1L1/SHC1/NPTN/RAB11A/BOC/PTK2/FGFR2/TIAM1/NR4A3/BDNF/EVL/SEMA7A/GDI1/B4GALT6/TNFRSF12A/ETV1/CDK5R1/LINGO1/RYK/CCKAR/VASP/NOTCH1/MAP1A/EXT1/EPHB2/PIK3CD/ENAH/NR4A2/PICALM/FLOT1/SEMA4G/FYN/ZFYVE27/LYPLA2/EPHA4/MYCBP2/ISL2/SPTA1/NIN/HOXA2/PIK3CA/STXBP1/TUBB3/TTL/ADARB1	68
BP	GO:0003177	pulmonary valve development	6/2159	21/18670	0.02783	0.3229	0.2991	TNFRSF1B/SLIT2/JAG1/HEY2/RBPJ/NOTCH1	6
BP	GO:0042135	neurotransmitter catabolic process	6/2159	21/18670	0.02783	0.3229	0.2991	ALDH5A1/ALDH7A1/MAOA/ABAT/DMGDH/POR	6
BP	GO:0034976	response to endoplasmic reticulum stress	44/2159	285/18670	0.02803	0.3246	0.3007	EDEM3/CCND1/JUN/NUPR1/CREB3L4/TMTC3/DDIT3/CDK5RAP3/RNF185/VAPB/CAV1/UBE4B/TOR1A/FBXO17/NFE2L1/CALR3/SESN2/PMAIP1/ATF6B/CASP4/FBXO6/TATDN2/TNFRSF10B/SHC1/MAP3K5/PARP16/PPP2CB/DDX11/ATXN3/TMEM33/BCL2L1/DNAJB14/RNFT1/MAN1B1/APAF1/FLOT1/UFC1/EXTL2/TMX1/IGFBP1/TMUB2/JKAMP/MANF/TRIM13	44
BP	GO:0044773	mitotic DNA damage checkpoint	18/2159	97/18670	0.02835	0.3271	0.303	CCND1/CCNB1/CDK5RAP3/RFWD3/CDKN1B/PCBP4/CNOT6L/RPA2/CNOT6/DONSON/HMGA2/TFDP2/MUC1/GADD45A/E2F4/RAD9A/CDC25C/STK33	18
BP	GO:0006261	DNA-dependent DNA replication	26/2159	153/18670	0.02837	0.3271	0.303	BAZ1A/POLG/DBF4/HMGA1/RECQL/PRIM1/SLFN11/RFWD3/SMC3/ORC2/BCL6/POLB/PRIMPOL/MCM9/RPA2/ORC4/DONSON/FEN1/DDX11/FGFR1/MCMDC2/ZPR1/RPA1/CDC7/POLE3/WRN	26
BP	GO:0034470	ncRNA processing	57/2159	384/18670	0.02863	0.3271	0.303	AGO2/ELP4/PUS10/TRMT6/RSL1D1/DIMT1/TP53RK/OSGEPL1/NOL8/LYAR/RPS24/NVL/SEPHS2/WDR36/UTP3/RRP15/BCDIN3D/DROSHA/NSUN2/ESF1/ELAC1/EXOSC8/RRNAD1/POLR3K/INTS2/PARN/LSM6/ZNHIT6/FAM207A/SRRT/MPHOSPH6/RIOK1/PES1/TRMT10C/BYSL/NOP10/TYW1/UTP15/PIH1D2/RCL1/LCMT2/FAM98B/NAF1/RPUSD4/GTF2H5/TRMT1L/SEPHS1/OSGEP/EXOSC4/DDX21/GEMIN4/QTRT1/PA2G4/TRMT5/TRMU/EXOSC10/DUS1L	57
BP	GO:0006415	translational termination	19/2159	104/18670	0.02873	0.3271	0.303	MRPL40/MRPS6/OXA1L/MRPS18C/C12orf65/MRPL17/MRPS14/MRPS18A/GSPT1/MTRF1L/MRPL11/MRPL10/MRPS16/MRPL24/MRPS33/MRPS31/MRRF/MRPS36/MRPL2	19
BP	GO:0072175	epithelial tube formation	23/2159	132/18670	0.02902	0.3271	0.303	SIX1/MKS1/ABL1/IFT172/FZD2/LIAS/LMO4/SOX8/DEAF1/DVL3/FZD1/DVL2/SDC4/FGFR2/PHACTR4/LUZP1/VASP/IFT52/APAF1/SEC24B/CC2D2A/PRKACA/TSC1	23
BP	GO:0072329	monocarboxylic acid catabolic process	23/2159	132/18670	0.02902	0.3271	0.303	ABHD2/GCDH/ETFB/ECI1/IVD/ALDH5A1/ACACB/ECH1/DCXR/NUDT19/SESN2/PCCB/ABAT/PCK2/EHHADH/AKR1A1/MCEE/PECR/SLC25A17/ACAA1/ABHD3/ACOX3/HOGA1	23
BP	GO:0016575	histone deacetylation	15/2159	77/18670	0.02905	0.3271	0.303	SREBF1/SUDS3/PRKD1/UCN/BCL6/MIER2/TBL1XR1/C6orf89/MTA3/AKAP8/REST/HDAC2/MSL3/MTA2/BAZ2A	15
BP	GO:0030326	embryonic limb morphogenesis	22/2159	125/18670	0.02909	0.3271	0.303	MKS1/OSR2/HOXA11/HOXA10/GDF5/B9D1/RDH10/INTU/FGFR1/IMPAD1/TP63/NOTCH1/IFT52/ECE1/ROR2/PBX1/GNA12/TMEM231/HDAC2/TBX2/FRAS1/HOXC10	22
BP	GO:0035113	embryonic appendage morphogenesis	22/2159	125/18670	0.02909	0.3271	0.303	MKS1/OSR2/HOXA11/HOXA10/GDF5/B9D1/RDH10/INTU/FGFR1/IMPAD1/TP63/NOTCH1/IFT52/ECE1/ROR2/PBX1/GNA12/TMEM231/HDAC2/TBX2/FRAS1/HOXC10	22
BP	GO:0015931	nucleobase-containing compound transport	38/2159	241/18670	0.02924	0.3271	0.303	NPIPA1/ZNF593/SLC35D1/ALKBH5/U2AF1L4/RAE1/SNUPN/THOC6/AGFG1/MYO1C/AHCTF1/UPF2/EIF4E/DDX39A/SLC35B4/NUP35/XPO1/DDX19B/SLC25A25/SEH1L/HSF1/SLC35C1/SRSF11/UPF3B/FLOT1/NUP98/SLC25A17/SLC35A2/NUP153/SLC25A32/NXT1/PCID2/BICD2/SLC35E3/TSC1/RFTN2/SLC25A4/CALHM1	38
BP	GO:0046165	alcohol biosynthetic process	29/2159	175/18670	0.02925	0.3271	0.303	BMP2/SREBF1/FGF1/ACACB/NFKB1/GCH1/MVK/PPIP5K1/PCK2/PLCB1/ELOVL6/SPHK1/IMPA1/PCBD2/ARV1/PPIP5K2/IMPAD1/SPTLC2/SP1/IFNG/CLCN2/NUS1/GPAM/REST/QDPR/VDR/FDFT1/POR/MVD	29
BP	GO:0010498	proteasomal protein catabolic process	69/2159	477/18670	0.02926	0.3271	0.303	EDEM3/NUPR1/UBE2H/CCNB1/ANAPC16/TMTC3/DDIT3/RNF185/FBXO45/FBXL2/ARMC8/CAV1/TRIB1/WWTR1/UBE4B/PSME4/SMURF2/TOR1A/FBXO17/TMF1/PELI1/NFE2L1/FBXO33/PMAIP1/ZFAND2B/SOCS5/FBXO6/PSMC2/ENC1/SPOPL/DET1/ZNRF1/LTN1/TBL1XR1/KIF14/KCTD13/KCTD5/GIPC1/KLHL15/CUL3/UBE2S/PPP2CB/PSMD4/RHBDF1/CSNK1E/ATXN3/CCAR2/FBXL15/UBR1/NKD2/SMAD7/CEBPA/DNAJB14/MAP1A/RNFT1/MAN1B1/GNA12/FBXL22/DDA1/TRIB2/TMUB2/KLHL42/BIRC2/PRKACA/KCTD10/JKAMP/SPSB2/TRIM13/CDC27	69
BP	GO:0010952	positive regulation of peptidase activity	32/2159	197/18670	0.0296	0.3271	0.303	DDX3X/TANK/CFLAR/RIPK2/CAV1/TNFRSF10A/PSME4/BID/PMAIP1/CASP4/TNFRSF10B/EGLN3/PDCD5/TNFSF15/MAP3K5/ADRM1/TNFSF10/SEMG2/CASP9/HSPE1/AIM2/JAK2/KHDC1/HSF1/PICALM/ST20/APAF1/PPM1F/REST/FYN/EPHA4/CASC2	32
BP	GO:0016445	somatic diversification of immunoglobulins	13/2159	64/18670	0.02965	0.3271	0.303	CLCF1/PARP3/PAXIP1/POLL/BCL6/POLB/MLH1/TP53BP1/IL27RA/CTNNBL1/PMS2P3/PMS2P1/LIG4	13
BP	GO:0044783	G1 DNA damage checkpoint	13/2159	64/18670	0.02965	0.3271	0.303	CCND1/CCNB1/RFWD3/CDKN1B/PCBP4/CNOT6L/RPA2/CNOT6/TFDP2/MUC1/GADD45A/E2F4/CDC25C	13
BP	GO:0046782	regulation of viral transcription	13/2159	64/18670	0.02965	0.3271	0.303	JUN/CHD1/POLR2I/HMGA2/GTF2F2/MID2/SP1/SNW1/POLR2G/SMARCA4/REST/CCNT1/TRIM13	13
BP	GO:0046834	lipid phosphorylation	13/2159	64/18670	0.02965	0.3271	0.303	PIP5KL1/SOCS5/SOCS3/SPHK1/IMPA1/SOCS7/IMPAD1/PIP4K2A/FAM126A/PIK3CD/PIK3C2B/PIP5K1A/PIK3CA	13
BP	GO:0010507	negative regulation of autophagy	16/2159	84/18670	0.02996	0.3271	0.303	NUPR1/MCL1/TAB3/FOXK2/MTMR9/KDM4A/PTK2/ZKSCAN3/GOLGA2/CPTP/USP30/HERC1/POLDIP2/PIK3CA/TSC1/NAMPT	16
BP	GO:0006047	UDP-N-acetylglucosamine metabolic process	5/2159	16/18670	0.03014	0.3271	0.303	UAP1/GFPT2/GNE/UAP1L1/GNPNAT1	5
BP	GO:0006086	acetyl-CoA biosynthetic process from pyruvate	5/2159	16/18670	0.03014	0.3271	0.303	PDP2/GSTZ1/PDK2/DLAT/PDP1	5
BP	GO:0051447	negative regulation of meiotic cell cycle	5/2159	16/18670	0.03014	0.3271	0.303	DUSP1/LIF/PRKAR1A/OVOL1/NPR2	5
BP	GO:0072109	glomerular mesangium development	5/2159	16/18670	0.03014	0.3271	0.303	EGR1/CFLAR/FOXC2/NOTCH1/PDGFRB	5
BP	GO:0003264	regulation of cardioblast proliferation	4/2159	11/18670	0.03015	0.3271	0.303	SIX1/MKS1/HES1/NOTCH1	4
BP	GO:0006048	UDP-N-acetylglucosamine biosynthetic process	4/2159	11/18670	0.03015	0.3271	0.303	UAP1/GFPT2/UAP1L1/GNPNAT1	4
BP	GO:0006183	GTP biosynthetic process	4/2159	11/18670	0.03015	0.3271	0.303	IMPDH2/NME5/NME3/NME6	4
BP	GO:0009125	nucleoside monophosphate catabolic process	4/2159	11/18670	0.03015	0.3271	0.303	NT5E/AMPD3/DNPH1/NUDT11	4
BP	GO:0009629	response to gravity	4/2159	11/18670	0.03015	0.3271	0.303	FOSL1/FOS/STX1A/PKM	4
BP	GO:0045628	regulation of T-helper 2 cell differentiation	4/2159	11/18670	0.03015	0.3271	0.303	IL4R/PRKCZ/SOCS5/BCL6	4
BP	GO:0060379	cardiac muscle cell myoblast differentiation	4/2159	11/18670	0.03015	0.3271	0.303	RBPJ/NOTCH1/REST/TBX2	4
BP	GO:0060837	blood vessel endothelial cell differentiation	4/2159	11/18670	0.03015	0.3271	0.303	HEY2/RBPJ/CCM2/NOTCH1	4
BP	GO:0061314	Notch signaling involved in heart development	4/2159	11/18670	0.03015	0.3271	0.303	JAG1/HEY2/RBPJ/NOTCH1	4
BP	GO:2000786	positive regulation of autophagosome assembly	4/2159	11/18670	0.03015	0.3271	0.303	ULK1/LRSAM1/RALB/PIP4K2A	4
BP	GO:0048538	thymus development	10/2159	45/18670	0.03019	0.3271	0.303	SIX1/ABL1/ZBTB1/EPHB3/HES1/LMO4/MAP2K1/PBX1/HOXA3/CRKL	10
BP	GO:0006735	NADH regeneration	7/2159	27/18670	0.03025	0.3271	0.303	HK1/FOXK2/PKM/ADPGK/PFKP/HK2/PFKM	7
BP	GO:0036475	neuron death in response to oxidative stress	7/2159	27/18670	0.03025	0.3271	0.303	MCL1/FZD1/NR4A3/TLR4/LANCL1/REST/TSC1	7
BP	GO:0061621	canonical glycolysis	7/2159	27/18670	0.03025	0.3271	0.303	HK1/FOXK2/PKM/ADPGK/PFKP/HK2/PFKM	7
BP	GO:0061718	glucose catabolic process to pyruvate	7/2159	27/18670	0.03025	0.3271	0.303	HK1/FOXK2/PKM/ADPGK/PFKP/HK2/PFKM	7
BP	GO:0000082	G1/S transition of mitotic cell cycle	43/2159	279/18670	0.03034	0.3274	0.3034	DDX3X/CCND1/DBF4/CCNB1/JADE1/PRIM1/SLFN11/CRLF3/CDK4/HINFP/RFWD3/BID/CDKN1B/ORC2/CDKN2D/ID2/ADAM17/KMT2E/APEX1/PLCB1/PCBP4/CNOT6L/RPA2/CDKN2C/KIF14/CNOT6/ORC4/TFDP2/CUL3/MUC1/GADD45A/EIF4E/RB1/GSPT1/CCND3/ZPR1/E2F4/RPA1/CDC25C/CDKN2B/CDK6/CDC7/POLE3	43
BP	GO:1990845	adaptive thermogenesis	26/2159	154/18670	0.03051	0.3287	0.3045	MAP2K6/PRKAB2/IL4R/GADD45G/G0S2/DDIT3/GRB10/CAV1/TLE3/APPL2/DOCK7/EPAS1/ADAM17/ELOVL6/RBPJ/ACOT13/FOXC2/JAK2/RB1/OMA1/TLR4/PRDM16/NOTCH1/HSF1/THRA/HOXC10	26
BP	GO:0071236	cellular response to antibiotic	25/2159	147/18670	0.03085	0.329	0.3048	ABL1/EGR1/CCL7/DNMT3A/AQP1/CDKN1B/DAXX/RELA/PPIF/SLC9A1/APEX1/SPHK1/MAP3K5/NR4A3/OSER1/DDX11/ECT2/TNFAIP3/ID3/IMPACT/HSF1/SETX/JAGN1/HDAC2/ZNF580	25
BP	GO:0031062	positive regulation of histone methylation	9/2159	39/18670	0.03094	0.329	0.3048	RNF20/DNMT1/TET1/PAXIP1/KMT2E/PHF1/ZNF304/SNW1/PAXBP1	9
BP	GO:0048713	regulation of oligodendrocyte differentiation	9/2159	39/18670	0.03094	0.329	0.3048	TNFRSF1B/HES1/ID2/NKX2-2/ZNF488/NOTCH1/WDR1/HDAC2/DAAM2	9
BP	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	9/2159	39/18670	0.03094	0.329	0.3048	CFLAR/ICAM1/TNFRSF10A/TNFRSF10B/ITPRIP/TNFSF10/HMGB2/TNFAIP3/BCL2L1	9
BP	GO:2000826	regulation of heart morphogenesis	9/2159	39/18670	0.03094	0.329	0.3048	SIX1/BMP2/MKS1/HES1/JAG1/RBPJ/FOXC2/NOTCH1/TBX2	9
BP	GO:0036003	positive regulation of transcription from RNA polymerase II promoter in response to stress	8/2159	33/18670	0.03109	0.329	0.3048	DDIT3/SESN2/ATF6B/RBPJ/HSF2/MUC1/NOTCH1/HSF1	8
BP	GO:0042339	keratan sulfate metabolic process	8/2159	33/18670	0.03109	0.329	0.3048	ST3GAL2/B4GALT3/CHST2/ST3GAL1/B3GNT2/B4GALT5/B4GALT6/OMD	8
BP	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	8/2159	33/18670	0.03109	0.329	0.3048	DCP1A/EXOSC8/CNOT6/LSM6/LSM2/TTC37/EXOSC4/LSM4	8
BP	GO:0048536	spleen development	8/2159	33/18670	0.03109	0.329	0.3048	ABL1/RBM15/NFKB2/POLB/ADAM17/PBX1/CDKN2B/PCID2	8
BP	GO:1901890	positive regulation of cell junction assembly	8/2159	33/18670	0.03109	0.329	0.3048	ABL1/MAP4K4/CAV1/EPHA2/SDC4/FLOT1/PPM1F/TSC1	8
BP	GO:0045862	positive regulation of proteolysis	54/2159	363/18670	0.03127	0.3299	0.3057	TNFRSF1B/DDX3X/TANK/TNIP1/NUPR1/MMP14/CFLAR/TMTC3/RNF185/RIPK2/CAV1/TNFRSF10A/TRIB1/PSME4/BID/PMAIP1/SOCS5/CASP4/PSMC2/DET1/TNFRSF10B/EGLN3/PTK2/PDCD5/TNFSF15/MAP3K5/ADRM1/TNFSF10/SEMG2/CASP9/HSPE1/FURIN/AIM2/CSNK1E/JAK2/ATXN3/IFNG/KHDC1/NKD2/SMAD7/CEBPA/HSF1/RNFT1/PICALM/ST20/APAF1/PPM1F/REST/DDA1/TRIB2/FYN/HDAC2/EPHA4/CASC2	54
BP	GO:0030323	respiratory tube development	29/2159	176/18670	0.03128	0.3299	0.3057	SPRY2/SREBF1/LIF/MMP14/HES1/FGF1/RDH10/HOXA5/EPAS1/JMJD6/FGF7/MAP2K1/ADA/RBPJ/FGFR2/ERRFI1/FSTL3/YAP1/EIF4E/FGFR1/PDPN/CEBPA/NOTCH1/PDGFRB/THRA/MAN2A1/SEC24B/FOXF1/PGR	29
BP	GO:0015748	organophosphate ester transport	19/2159	105/18670	0.03141	0.3301	0.3059	ATP8B1/TMEM30B/ATP10D/PITPNB/GLTP/PLEKHA3/MFSD2A/APOC3/ATP11B/SLC37A4/ATP8B3/TMEM30A/CPTP/PITPNC1/SLC25A25/SLC25A17/SLC25A32/SLC25A4/CALHM1	19
BP	GO:0032006	regulation of TOR signaling	19/2159	105/18670	0.03141	0.3301	0.3059	NIM1K/EPM2A/SESN2/MAPKAPK5/FNIP2/SESN3/LAMTOR3/LAMTOR4/MLST8/RICTOR/UBR1/SEH1L/GOLPH3/GNA12/SIK3/DEPTOR/RRAGC/PIK3CA/TSC1	19
BP	GO:0048706	embryonic skeletal system development	22/2159	126/18670	0.03153	0.3304	0.3061	SIX1/MKS1/OSR2/MMP14/HOXA11/HOXA1/SLC35D1/HOXA7/RDH10/HOXA5/HOXA6/ACVR2A/DEAF1/SATB2/FGFR2/FOXC2/GSC/EXT1/PBX1/HOXA3/HOXA2/HOXD4	22
BP	GO:0006354	DNA-templated transcription, elongation	20/2159	112/18670	0.03157	0.3304	0.3061	ELP4/LDB1/ERCC6/EAF1/MLLT1/AFF4/POLR1E/POLR2I/ADRM1/CDK12/GTF2F2/SCAF8/CCAR2/POLR1C/ELL/POLR2G/GTF2H5/EAPP/PCID2/CCNT1	20
BP	GO:0001952	regulation of cell-matrix adhesion	21/2159	119/18670	0.0316	0.3304	0.3061	ABL1/MAP4K4/SLK/MACF1/MMP14/LDB1/PEAK1/JAG1/HOXA7/DUSP3/PRKCZ/BCL6/BCAS3/SLC9A1/PTK2/SDC4/PPM1F/RASA1/CDK6/PHLDB2/TSC1	21
BP	GO:0060538	skeletal muscle organ development	28/2159	169/18670	0.03181	0.3314	0.3071	FOS/SIX1/MAFF/HIVEP3/EGR1/NUPR1/CFLAR/EGR2/NR1D2/CAV1/AKIRIN1/MYOM2/HOMER1/HLF/BCL9L/SOX8/NR2F2/MEF2D/EOMES/MYL6B/FOXN2/RB1/NOTCH1/KLF5/FLOT1/MYOZ2/ANKRD1/DDX5	28
BP	GO:0140056	organelle localization by membrane tethering	28/2159	169/18670	0.03181	0.3314	0.3071	MKS1/VAPB/STX6/B9D1/RALB/STX1A/VPS11/ODF2/RAB11A/TUBB4B/HAUS5/CEP70/CEP57/MAPRE1/HAUS6/CSNK1E/SNPH/SYTL2/RAB8B/TUBA4A/EXOC5/CC2D2A/PRKACA/STXBP1/CEP89/SDCCAG8/HAUS3/VPS45	28
BP	GO:0021954	central nervous system neuron development	15/2159	78/18670	0.03225	0.3355	0.3108	EPHB3/FBXO45/SLIT2/B4GALT5/PTK2/FGFR2/B4GALT6/ATF5/EPHB2/NR4A2/CRKL/EPHA4/MYCBP2/NIN/ADARB1	15
BP	GO:0043401	steroid hormone mediated signaling pathway	30/2159	184/18670	0.0328	0.34	0.315	ABHD2/CBFB/ZBTB7A/FOXP1/PGRMC2/NR1D2/LBH/UFSP2/DAXX/NR2F2/TGFB1I1/NR4A3/YAP1/JAK2/TRIM68/NR3C1/TP63/RB1/NR2F1/THRA/NR4A2/GPAM/SMARCA4/STRN3/VDR/NR2C2/PGR/NR3C2/DDX5/CRY1	30
BP	GO:2000045	regulation of G1/S transition of mitotic cell cycle	30/2159	184/18670	0.0328	0.34	0.315	DDX3X/CCND1/CCNB1/JADE1/SLFN11/CDK4/RFWD3/BID/CDKN1B/CDKN2D/ID2/ADAM17/KMT2E/APEX1/PLCB1/PCBP4/CNOT6L/RPA2/CDKN2C/KIF14/CNOT6/TFDP2/MUC1/GADD45A/RB1/CCND3/E2F4/CDC25C/CDKN2B/CDK6	30
BP	GO:0060421	positive regulation of heart growth	11/2159	52/18670	0.03316	0.3414	0.3163	CCNB1/PARP2/ACACB/HEY2/RBPJ/FGFR2/YAP1/FGFR1/NOTCH1/TBX2/IGF1	11
BP	GO:0099518	vesicle cytoskeletal trafficking	11/2159	52/18670	0.03316	0.3414	0.3163	SYBU/PRKCZ/MYO1C/SNAPIN/KIF5B/MYO5A/DTNBP1/AP3M2/WASL/CLN3/BLOC1S2	11
BP	GO:2000677	regulation of transcription regulatory region DNA binding	11/2159	52/18670	0.03316	0.3414	0.3163	LIF/ZBTB7A/TRIM6/DDIT3/ZNF593/DOT1L/HEY2/HMGA2/RB1/IFNG/IGF1	11
BP	GO:2000772	regulation of cellular senescence	11/2159	52/18670	0.03316	0.3414	0.3163	ABL1/HMGA1/RSL1D1/ARG2/BCL6/MAP3K3/HMGA2/ZKSCAN3/YPEL3/CDK6/NAMPT	11
BP	GO:0017038	protein import	32/2159	199/18670	0.03354	0.3448	0.3194	KPNA2/RBM22/KPNA4/APPL2/PEX12/SNUPN/DNAJC19/PDCD5/HEATR3/TXNIP/TNPO3/ECT2/IPO4/NUP35/IFNG/TIMM10/SAMM50/RAB23/PEX16/AGTR2/KPNA1/ZPR1/RAB8B/DMAP1/GRPEL1/NUP98/NUP153/PEX1/DNLZ/FAM53C/NXT1/RANBP6	32
BP	GO:0050673	epithelial cell proliferation	63/2159	434/18670	0.03371	0.3459	0.3204	EGR3/SIX1/BMP2/CCND1/JUN/OSR2/NUPR1/MMP14/IFT172/GDF5/CFLAR/ITGB3/HES1/FGF1/CAV1/EPHA2/CXCL12/CDKN1C/PRKD1/CDKN1B/HOXA5/TCF7L2/TNFSF11/SERPINB1/ACVR2A/NR2F2/ID2/DEAF1/FGF7/ADAM17/MAP2K1/EREG/PGF/FGFR2/NLRC3/LIMS2/NR4A3/NRAS/C6orf89/ERRFI1/ZNF304/INTU/YAP1/RICTOR/HMGB2/IFT74/TNFAIP3/FGFR1/SP1/TP63/RB1/NOTCH1/IFT52/CDKN2B/ZNF580/VDR/MAGED1/CDK6/PGR/HRAS/BCL2L2/VEGFC/IGF1	63
BP	GO:0030838	positive regulation of actin filament polymerization	18/2159	99/18670	0.03406	0.3488	0.3231	ICAM1/ARF6/JMY/RHOBTB1/ARPC5L/ARPC5/GMFB/FMN2/EVL/ARPC2/MYO1C/FCHSD2/RICTOR/PFN2/ARPC4/VASP/WASL/CDC42EP2	18
BP	GO:1901989	positive regulation of cell cycle phase transition	19/2159	106/18670	0.03427	0.3488	0.3231	DDX3X/CCND1/CCNB1/CDK4/ADAM17/KMT2E/APEX1/PLCB1/RAB11A/NSMCE2/CUL3/MTA3/RAD51C/RB1/TMOD3/CCND3/PBX1/CDC25C/CDC7	19
BP	GO:0009100	glycoprotein metabolic process	61/2159	419/18670	0.03437	0.3488	0.3231	BMP2/EDEM3/AGO2/TNIP1/PHLDA1/CHST7/ST3GAL2/ALG13/B4GALT3/GLCE/TMTC3/GFPT2/RNF185/B3GNT9/SLC35D1/TET1/CHST14/FBXO17/ST3GAL1/B3GNT2/FUT4/EOGT/TCF7L2/GCNT3/CHST10/B4GALT5/TMTC2/FBXO6/PLCB1/HBEGF/FUT11/FUT8/UGDH/B4GALT6/FOXL1/POMGNT1/GALNT15/GOLGA2/HS2ST1/MUC1/FAM20B/CSGALNACT2/IMPAD1/GBGT1/EXT1/SLC35C1/GOLPH3/NUS1/CHST15/MAN1B1/ST6GALNAC1/EXTL2/MAN2A1/GXYLT2/MGAT5/PMM1/MVD/HS3ST3A1/CHST12/TRIM13/IGF1	61
BP	GO:0006085	acetyl-CoA biosynthetic process	6/2159	22/18670	0.03463	0.3488	0.3231	PDP2/GSTZ1/PDK2/DLAT/PDP1/PPCS	6
BP	GO:0006783	heme biosynthetic process	6/2159	22/18670	0.03463	0.3488	0.3231	COX15/SLC25A38/NFE2L1/ALAS1/CPOX/SLC11A2	6
BP	GO:0007289	spermatid nucleus differentiation	6/2159	22/18670	0.03463	0.3488	0.3231	PSME4/TMF1/SRPK1/AGFG1/HMGB2/PYGO1	6
BP	GO:0034311	diol metabolic process	6/2159	22/18670	0.03463	0.3488	0.3231	GCH1/SGPP1/SPHK1/PCBD2/SPTLC2/QDPR	6
BP	GO:0045649	regulation of macrophage differentiation	6/2159	22/18670	0.03463	0.3488	0.3231	ZBTB46/LIF/TRIB1/ID2/RB1/ROR2	6
BP	GO:0090312	positive regulation of protein deacetylation	6/2159	22/18670	0.03463	0.3488	0.3231	SREBF1/PRKD1/BCL6/C6orf89/IFNG/AKAP8	6
BP	GO:0140112	extracellular vesicle biogenesis	6/2159	22/18670	0.03463	0.3488	0.3231	VPS4A/RAB11A/SDC4/ATP13A2/IFNG/ARRDC1	6
BP	GO:1901798	positive regulation of signal transduction by p53 class mediator	6/2159	22/18670	0.03463	0.3488	0.3231	SPRED1/CDK5RAP3/PMAIP1/SPRED2/ANKRD1/DDX5	6
BP	GO:0006643	membrane lipid metabolic process	33/2159	207/18670	0.03486	0.3506	0.3248	SAMD8/ST3GAL2/B4GALT3/PRKD3/MPPE1/VAPB/ALDH5A1/PIGC/PGAP2/PRKD1/GLTP/B4GALT5/ELOVL7/SGPP1/ELOVL6/SPHK1/VAPA/NEU1/KDSR/ARV1/B4GALT6/SPTLC2/CPTP/PIGB/DEGS1/GBGT1/PIGV/PGAP3/SUMF2/ELOVL4/CLN3/CREM/MGST2	33
BP	GO:0015711	organic anion transport	69/2159	482/18670	0.0356	0.3552	0.3291	BDKRB2/MAP2K6/NFKBIE/PRKAB2/ATP8B1/ABCC5/TMEM30B/ATP10D/SLC25A22/RGS4/SLCO4A1/PITPNB/SLC7A4/LRRC8A/SLC35D1/SLC7A6/ACACB/SLC25A38/SLCO3A1/AQP1/NFE2L1/TNFSF11/GLTP/SLC16A14/PLEKHA3/MFSD2A/SLC19A2/CTNS/ABAT/SLC4A7/STX1A/SLC1A1/APOC3/SLC10A7/ATP11B/SFXN1/GIPC1/SLC37A4/SLC1A4/SLC26A4/CYB5RL/ATP8B3/TMEM30A/RGS2/SLC35B4/SLC26A1/PDPN/CPTP/PITPNC1/GRM2/SLC23A2/SLC25A25/AGTR2/SLC38A2/SLC25A17/PLA2G12A/SLC35A2/CYB5R4/SLC25A32/SLC46A1/SLC6A1/CLN3/SLC16A6/SLC43A2/ACSL4/SLC52A2/STXBP1/SLC25A4/CALHM1	69
BP	GO:0007032	endosome organization	15/2159	79/18670	0.03571	0.3552	0.3291	CHMP7/STX6/PLEKHF1/HOOK2/VPS25/HOOK3/VPS11/VPS4A/AKTIP/RAB11A/RAB22A/SNX10/VPS37A/VPS28/LAPTM4B	15
BP	GO:0032956	regulation of actin cytoskeleton organization	51/2159	343/18670	0.03575	0.3552	0.3291	ABL1/VILL/ARHGAP28/ICAM1/ARF6/RGS4/SLIT2/FHOD1/TMOD2/CXCL12/JMY/F2RL1/RHOBTB1/ARPC5L/BCAS3/SLC9A1/ARHGDIA/ARPC5/GMFB/RHOG/FMN2/SDC4/FRMD7/PFN4/EVL/ARPC2/MYO1C/MLST8/FCHSD2/CDK5R1/RICTOR/ECT2/PFN2/ARPC4/VASP/PDGFRB/TMOD3/RHOQ/TRIOBP/RHOC/PREX1/WDR1/PPM1F/SH3PXD2B/WASL/RASA1/CDC42EP2/SPTA1/HRAS/PHLDB2/TSC1	51
BP	GO:0032008	positive regulation of TOR signaling	9/2159	40/18670	0.03597	0.3552	0.3291	LAMTOR3/LAMTOR4/MLST8/RICTOR/SEH1L/GOLPH3/SIK3/RRAGC/PIK3CA	9
BP	GO:0035315	hair cell differentiation	9/2159	40/18670	0.03597	0.3552	0.3291	HES1/JAG1/SLC4A7/HEY2/RBPJ/FGFR1/NOTCH1/TRIOBP/SEC24B	9
BP	GO:0090184	positive regulation of kidney development	9/2159	40/18670	0.03597	0.3552	0.3291	SIX1/LIF/EGR1/CFLAR/SOX8/CD24/PDGFRB/AGTR2/MAGED1	9
BP	GO:0046467	membrane lipid biosynthetic process	24/2159	142/18670	0.03612	0.3552	0.3291	SAMD8/ST3GAL2/B4GALT3/PRKD3/MPPE1/VAPB/PIGC/PGAP2/PRKD1/B4GALT5/ELOVL7/SGPP1/ELOVL6/SPHK1/VAPA/KDSR/B4GALT6/SPTLC2/PIGB/DEGS1/GBGT1/PIGV/PGAP3/ELOVL4	24
BP	GO:0072006	nephron development	24/2159	142/18670	0.03612	0.3552	0.3291	SIX1/BMP2/LIF/EGR1/HOXA11/CFLAR/HES1/FGF1/JAG1/WWTR1/SOX8/PGF/KLHL3/FOXC2/MAGI2/FAT4/YAP1/MPV17/NOTCH1/CD24/PDGFRB/AGTR2/PBX1/MAGED1	24
BP	GO:0010810	regulation of cell-substrate adhesion	34/2159	215/18670	0.03613	0.3552	0.3291	ABL1/MAP4K4/SLK/MACF1/MMP14/LDB1/ECM2/PEAK1/JAG1/HOXA7/DUSP3/PRKCZ/BCL6/BCAS3/SLC9A1/PTK2/SDC4/LIMS2/ARPC2/JAK2/ATXN3/PDPN/NOTCH1/TRIOBP/PREX1/ABI3BP/PPM1F/CRKL/FOXF1/RASA1/CDK6/PHLDB2/TSC1/EMILIN1	34
BP	GO:0033137	negative regulation of peptidyl-serine phosphorylation	7/2159	28/18670	0.03644	0.3552	0.3291	BDKRB2/CAV1/PDE4D/GPD1L/INPP5F/SMAD7/PPM1F	7
BP	GO:0051984	positive regulation of chromosome segregation	7/2159	28/18670	0.03644	0.3552	0.3291	CCNB1/FEN1/NSMCE2/CUL3/DDX11/RB1/RAD21	7
BP	GO:0060122	inner ear receptor cell stereocilium organization	7/2159	28/18670	0.03644	0.3552	0.3291	MKS1/HES1/IFT88/SDC4/FAT4/TRIOBP/SEC24B	7
BP	GO:0061615	glycolytic process through fructose-6-phosphate	7/2159	28/18670	0.03644	0.3552	0.3291	HK1/FOXK2/PKM/ADPGK/PFKP/HK2/PFKM	7
BP	GO:0061620	glycolytic process through glucose-6-phosphate	7/2159	28/18670	0.03644	0.3552	0.3291	HK1/FOXK2/PKM/ADPGK/PFKP/HK2/PFKM	7
BP	GO:0090344	negative regulation of cell aging	7/2159	28/18670	0.03644	0.3552	0.3291	ABL1/BCL6/MAP3K3/HMGA2/ZKSCAN3/CDK6/NAMPT	7
BP	GO:1990776	response to angiotensin	7/2159	28/18670	0.03644	0.3552	0.3291	CAV1/NFKB1/RELA/AGTRAP/ARID1B/AGTR2/HSF1	7
BP	GO:0006400	tRNA modification	16/2159	86/18670	0.03644	0.3552	0.3291	ELP4/PUS10/TRMT6/OSGEPL1/SEPHS2/BCDIN3D/NSUN2/TRMT10C/LCMT2/TRMT1L/SEPHS1/OSGEP/QTRT1/TRMT5/TRMU/DUS1L	16
BP	GO:0007260	tyrosine phosphorylation of STAT protein	16/2159	86/18670	0.03644	0.3552	0.3291	GHR/LIF/HES1/CAV1/CLCF1/SOCS3/SH2B3/JAK2/IL22RA2/INPP5F/IFNG/HSF1/IL12A/FYN/HDAC2/IGF1	16
BP	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	16/2159	86/18670	0.03644	0.3552	0.3291	DDX3X/CFLAR/ICAM1/TNFRSF10A/BID/FEM1B/DAXX/PMAIP1/TNFRSF10B/ITPRIP/TNFSF10/HMGB2/TNFAIP3/BCL2L1/GABARAP/BLOC1S2	16
BP	GO:0017004	cytochrome complex assembly	8/2159	34/18670	0.03667	0.3568	0.3306	COX15/COA5/OXA1L/BCS1L/UQCC1/TTC19/UQCR10/SURF1	8
BP	GO:0070498	interleukin-1-mediated signaling pathway	18/2159	100/18670	0.03721	0.3609	0.3344	EGR1/RIPK2/IL1RN/OTUD4/TAB3/PSME4/PELI1/NFKB1/RELA/PSMC2/MAP3K3/PLCB1/CHUK/IRAK4/UBE2N/PSMD4/IRAK2/PELI3	18
BP	GO:0090174	organelle membrane fusion	18/2159	100/18670	0.03721	0.3609	0.3344	TAP2/STX6/TMEM175/STX1A/C2CD5/VPS11/VPS4A/SPHK1/VPS8/MFN1/SNAPIN/KIF5B/NKD2/RAB8B/VAV3/VAMP4/GNAI3/STXBP1	18
BP	GO:0030258	lipid modification	37/2159	238/18670	0.03751	0.3632	0.3365	ST3GAL2/GCDH/ETFB/ECI1/SYNJ2/IVD/ACACB/APPL2/ECH1/PIP5KL1/SESN2/MTMR3/SOCS5/MTMR9/SOCS3/EHHADH/SPHK1/IMPA1/NR4A3/SOCS7/IMPAD1/INPP5F/PIP4K2A/FAM126A/GBGT1/INPP5B/SLC35C1/PIK3CD/PECR/PIK3C2B/SLC25A17/MTMR7/PIP5K1A/ACAA1/POR/ACOX3/PIK3CA	37
BP	GO:0031122	cytoplasmic microtubule organization	11/2159	53/18670	0.03763	0.3632	0.3365	SLK/IFT172/HOOK2/HOOK3/KATNAL2/RAB11A/FIGN/CEP120/STMN3/CRIPT/WDR73	11
BP	GO:0050704	regulation of interleukin-1 secretion	11/2159	53/18670	0.03763	0.3632	0.3365	FOXP1/RIPK2/ARG2/HK1/PANX1/SERPINB1/AIM2/TNFAIP3/TLR4/CPTP/TRIM16	11
BP	GO:0071774	response to fibroblast growth factor	25/2159	150/18670	0.03826	0.3686	0.3415	EGR3/IER2/SPRY2/SPRED1/SPRY4/FGF1/FGF7/POLR2I/SPRED2/NPTN/FGFBP3/FGFR2/ELK1/CEP57/SHISA2/FAT4/CD44/GTF2F2/KIF16B/DSTYK/FGFR1/POLR2G/SETX/FLRT1/CRKL	25
BP	GO:0045685	regulation of glial cell differentiation	14/2159	73/18670	0.0385	0.3686	0.3415	TNFRSF1B/BMP2/LIF/HES1/CLCF1/RELA/ID2/NKX2-2/ZNF488/NOTCH1/WDR1/HDAC2/DAAM2/EPHA4	14
BP	GO:0006266	DNA ligation	5/2159	17/18670	0.03874	0.3686	0.3415	PARP3/POLB/HMGB2/LIG4/TFIP11	5
BP	GO:0030011	maintenance of cell polarity	5/2159	17/18670	0.03874	0.3686	0.3415	LIN7C/SLC9A1/ARPC5/LIN7A/WDR1	5
BP	GO:0042249	establishment of planar polarity of embryonic epithelium	5/2159	17/18670	0.03874	0.3686	0.3415	FZD2/DVL3/FZD1/DVL2/SEC24B	5
BP	GO:0070131	positive regulation of mitochondrial translation	5/2159	17/18670	0.03874	0.3686	0.3415	RMND1/UQCC1/TRMT10C/NGRN/RPUSD4	5
BP	GO:0070525	tRNA threonylcarbamoyladenosine metabolic process	5/2159	17/18670	0.03874	0.3686	0.3415	TP53RK/OSGEPL1/TRMT10C/OSGEP/TRMT5	5
BP	GO:2000001	regulation of DNA damage checkpoint	5/2159	17/18670	0.03874	0.3686	0.3415	RFWD3/FEM1B/RPA2/CCAR2/CRY1	5
BP	GO:2000136	regulation of cell proliferation involved in heart morphogenesis	5/2159	17/18670	0.03874	0.3686	0.3415	SIX1/MKS1/HES1/RBPJ/NOTCH1	5
BP	GO:0018209	peptidyl-serine modification	48/2159	322/18670	0.03908	0.3713	0.344	BDKRB2/HIPK3/IKBKE/SPRY2/ULK1/LIF/TRIM6/CCNB1/ERCC6/RIPK2/MKNK2/PARP2/CAV1/TOP1/PRKD1/DOCK7/UCN/MAPKAPK5/PRKCZ/FNIP2/HIPK1/RPS6KA3/PDE4D/IL11/GPD1L/CHUK/HMGA2/PKN3/CD44/PRKCI/CDK5R1/RICTOR/PAK2/CSNK1E/PFN2/MARK3/IRGM/INPP5F/IFNG/SMAD7/TERF2IP/PPM1F/STK32A/SMYD3/CDC7/PRKACA/NLK/PIK3CA	48
BP	GO:0048194	Golgi vesicle budding	15/2159	80/18670	0.03942	0.374	0.3465	VAPB/SEC23IP/PEF1/TRAPPC6A/KLHL12/VAPA/SEC24A/PRKCI/PPP6R1/CUL3/SEC31B/GOLGA2/TRAPPC2L/GOLPH3/SEC24B	15
BP	GO:0090287	regulation of cellular response to growth factor stimulus	44/2159	292/18670	0.03996	0.3785	0.3507	ABL1/SPRY2/ZBTB7A/GDF5/SPRY4/CFLAR/ITGB3/HES1/GRB10/SLIT2/FGF1/CAV1/NRROS/LEMD3/FST/CDKN1C/SMURF2/BCL9L/ADAM17/RNF111/FZD1/NPTN/RBPJ/TGFB1I1/FGFBP3/SHISA2/GIPC1/MYO1C/FSTL3/NREP/GREM2/FBXL15/DSTYK/FGFR1/SNW1/PRDM16/SMAD7/NOTCH1/AGTR2/GLG1/PELO/CDKN2B/VEGFC/EMILIN1	44
BP	GO:0006906	vesicle fusion	17/2159	94/18670	0.04041	0.3809	0.3529	TAP2/STX6/TMEM175/STX1A/C2CD5/VPS11/VPS4A/SPHK1/VPS8/SNAPIN/KIF5B/NKD2/RAB8B/VAV3/VAMP4/GNAI3/STXBP1	17
BP	GO:0060993	kidney morphogenesis	17/2159	94/18670	0.04041	0.3809	0.3529	SIX1/BMP2/LIF/HOXA11/HES1/FGF1/WWTR1/GCNT3/SOX8/PGF/KLHL3/FAT4/PDGFRB/AGTR2/PBX1/MAGED1/FRAS1	17
BP	GO:1901216	positive regulation of neuron death	17/2159	94/18670	0.04041	0.3809	0.3529	FOS/ABL1/JUN/EGR1/NUPR1/DDIT3/MCL1/DAXX/MAP3K5/ELK1/CASP9/CDK5R1/TLR4/IFNG/PICALM/REST/FYN	17
BP	GO:1905330	regulation of morphogenesis of an epithelium	29/2159	180/18670	0.04051	0.3809	0.3529	SIX1/MKS1/ABL1/LIF/FOXP1/FZD2/FGF1/PSME4/SMURF2/ETV5/SOX8/PSMC2/FGF7/DVL3/FZD1/DVL2/TIAM1/MAGI2/PSMD4/RYK/AP2A2/FGFR1/AGTR2/AP2M1/ROR2/SEC24B/TBX2/MAGED1/PHLDB2	29
BP	GO:0043393	regulation of protein binding	34/2159	217/18670	0.04053	0.3809	0.3529	BMP2/ABL1/BTBD1/ADNP/ARF6/RIPK2/CAV1/TCF7L2/TNFSF11/NVL/RALB/AKTIP/STPG1/FRMD7/TIAM1/BDNF/MAPRE1/PPP2CB/SNAPIN/DDX11/CSNK1E/GOLGA2/GREM2/MARK3/UBASH3B/HSF1/FLOT1/DTNBP1/HOXA3/GAS8/EPHA4/SPTA1/PRKACA/TFIP11	34
BP	GO:0046390	ribose phosphate biosynthetic process	45/2159	300/18670	0.04073	0.381	0.353	ZBTB7A/NUPR1/GCDH/ACOT7/PDP2/HK1/ACACB/GSTZ1/PRKAG1/PDK2/PRPS1/PRPSAP2/IMPDH2/RAE1/PPCDC/ELOVL7/FOXK2/HSD17B8/PANK1/ELOVL6/AMPD3/PKM/ADPGK/RFK/PRPS2/PFKP/NUP35/SLC26A1/IFNG/SEH1L/DLAT/UCK1/NUP98/HK2/NME5/NME3/NUP153/NME6/PFKM/ELOVL4/PDP1/ACSL4/NPR2/IGF1/PPCS	45
BP	GO:0015980	energy derivation by oxidation of organic compounds	43/2159	285/18670	0.04114	0.381	0.353	GPD2/CCNB1/ETFB/IDH1/GFPT2/SLC25A22/CAT/ALDH5A1/NDUFV2/COX15/NOA1/BID/NDUFA6/TBRG4/ACO1/UCN/OXA1L/NDUFB5/PPP1R3E/CISD1/COX1/NR4A3/ENPP1/IDH3A/PHKB/IFNG/PRDM16/SLC25A25/MYBBP1A/NDUFS3/DLAT/UQCR10/MDH1B/NDUFV1/NDUFS2/ISCU/PHKA1/NDUFB10/NDUFA11/SURF1/PIK3CA/D2HGDH/IGF1	43
BP	GO:0002903	negative regulation of B cell apoptotic process	4/2159	12/18670	0.04118	0.381	0.353	FOXP1/BCL6/ADA/SLC39A10	4
BP	GO:0015867	ATP transport	4/2159	12/18670	0.04118	0.381	0.353	SLC25A25/SLC25A17/SLC25A4/CALHM1	4
BP	GO:0016188	synaptic vesicle maturation	4/2159	12/18670	0.04118	0.381	0.353	SNAPIN/DLG4/PICALM/STXBP1	4
BP	GO:0035751	regulation of lysosomal lumen pH	4/2159	12/18670	0.04118	0.381	0.353	TMEM175/SNAPIN/CCDC115/CLN3	4
BP	GO:0051549	positive regulation of keratinocyte migration	4/2159	12/18670	0.04118	0.381	0.353	MAP4K4/ARF6/FGF7/HBEGF	4
BP	GO:0060742	epithelial cell differentiation involved in prostate gland development	4/2159	12/18670	0.04118	0.381	0.353	FEM1B/FGFR2/TP63/NOTCH1	4
BP	GO:0072393	microtubule anchoring at microtubule organizing center	4/2159	12/18670	0.04118	0.381	0.353	HOOK3/BICD1/NIN/BICD2	4
BP	GO:1902337	regulation of apoptotic process involved in morphogenesis	4/2159	12/18670	0.04118	0.381	0.353	TNFRSF1B/FOXC2/NOTCH1/VDR	4
BP	GO:0046365	monosaccharide catabolic process	13/2159	67/18670	0.04146	0.3817	0.3537	RBKS/HK1/FUT4/DCXR/FOXK2/GALM/FUT8/AKR1A1/PKM/ADPGK/PFKP/HK2/PFKM	13
BP	GO:0050434	positive regulation of viral transcription	9/2159	41/18670	0.04152	0.3817	0.3537	JUN/CHD1/POLR2I/GTF2F2/SP1/SNW1/POLR2G/SMARCA4/CCNT1	9
BP	GO:1902893	regulation of pri-miRNA transcription by RNA polymerase II	9/2159	41/18670	0.04152	0.3817	0.3537	FOS/BMP2/SREBF1/JUN/RELA/NR3C1/KLF5/SMARCA4/TEAD1	9
BP	GO:0071214	cellular response to abiotic stimulus	49/2159	331/18670	0.04157	0.3817	0.3537	BDKRB2/DDX3X/RELB/TANK/ZBTB1/EGR1/ITGA2/TNFRSF10A/RAB11FIP5/AQP1/GPR68/NFKB1/SLC9A1/TNFRSF10B/CNN2/GPR88/HMGA2/ELK1/TP53BP1/CASP9/ERRFI1/YAP1/ECT2/PPEF1/GADD45A/BCL2L1/TLR4/SLC12A6/IMPACT/HSF1/C9orf116/SLC38A2/ST20/E2F4/SDE2/RAD9A/REST/GTF2H5/ANKRD1/MICU1/HRAS/POLE3/LIG4/WRN/CRY1/SWI5/NAMPT/USP28/SIPA1	49
BP	GO:0104004	cellular response to environmental stimulus	49/2159	331/18670	0.04157	0.3817	0.3537	BDKRB2/DDX3X/RELB/TANK/ZBTB1/EGR1/ITGA2/TNFRSF10A/RAB11FIP5/AQP1/GPR68/NFKB1/SLC9A1/TNFRSF10B/CNN2/GPR88/HMGA2/ELK1/TP53BP1/CASP9/ERRFI1/YAP1/ECT2/PPEF1/GADD45A/BCL2L1/TLR4/SLC12A6/IMPACT/HSF1/C9orf116/SLC38A2/ST20/E2F4/SDE2/RAD9A/REST/GTF2H5/ANKRD1/MICU1/HRAS/POLE3/LIG4/WRN/CRY1/SWI5/NAMPT/USP28/SIPA1	49
BP	GO:1902107	positive regulation of leukocyte differentiation	24/2159	144/18670	0.04167	0.382	0.354	FOS/EGR3/IL4R/ZBTB46/CBFB/ZBTB1/LIF/JUN/MMP14/RIPK2/TRIB1/CD27/TNFSF11/PRKCZ/SOCS5/BCL6/ID2/ADA/PNP/RB1/IFNG/ROR2/IL12A/PCID2	24
BP	GO:0001558	regulation of cell growth	60/2159	416/18670	0.04173	0.382	0.354	BDKRB1/DDX3X/ABL1/MACF1/MMP14/ADNP/JADE1/DCBLD2/PARP2/RGS4/SLIT2/CRLF3/CXCL12/TMEM97/CDKN1B/UCN/SESN2/CDKN2D/WDR36/BCL6/RPS6KA3/SLC9A1/IFRD1/ADAM17/HBEGF/RAB11A/SPHK1/NDRG3/CDKN2C/KIF14/BDNF/SEMA7A/ING1/SERTAD3/GDI1/ENPP1/TNFRSF12A/CDK5R1/RYK/CCAR2/RGS2/RB1/DNPH1/AGTR2/BLZF1/ATAD3A/NDUFS3/ST20/SMARCA4/IGFBP1/SEMA4G/OGFR/NME6/CRKL/ZFYVE27/EBAG9/EXOSC4/TTL/SIPA1/IGF1	60
BP	GO:0032799	low-density lipoprotein receptor particle metabolic process	6/2159	23/18670	0.04241	0.3857	0.3573	ITGB3/SEC24A/FURIN/AP2A2/AP2M1/HNRNPK	6
BP	GO:0072170	metanephric tubule development	6/2159	23/18670	0.04241	0.3857	0.3573	LIF/HES1/WWTR1/SOX8/FAT4/YAP1	6
BP	GO:0072243	metanephric nephron epithelium development	6/2159	23/18670	0.04241	0.3857	0.3573	LIF/HES1/WWTR1/SOX8/FAT4/YAP1	6
BP	GO:0097150	neuronal stem cell population maintenance	6/2159	23/18670	0.04241	0.3857	0.3573	HES1/JAG1/HOOK3/SRRT/NOTCH1/REST	6
BP	GO:0051353	positive regulation of oxidoreductase activity	11/2159	54/18670	0.0425	0.3857	0.3573	ABL1/PDP2/GCH1/RFK/IFNG/AGTR2/NUS1/VDR/POR/PDP1/GNAI3	11
BP	GO:0070373	negative regulation of ERK1 and ERK2 cascade	14/2159	74/18670	0.04262	0.3857	0.3573	DUSP6/ABL1/SPRY2/DUSP1/SPRED1/LIF/TNIP1/SPRY4/DUSP3/CAMK2N1/ERRFI1/TLR4/EPHB2/EMILIN1	14
BP	GO:0034142	toll-like receptor 4 signaling pathway	8/2159	35/18670	0.04288	0.3857	0.3573	RIPK2/TRIL/RAB11FIP2/APPL2/PELI1/F2RL1/TNFAIP3/TLR4	8
BP	GO:0042455	ribonucleoside biosynthetic process	8/2159	35/18670	0.04288	0.3857	0.3573	MTAP/NT5E/IMPDH2/ADA/UCK1/NME5/NME3/NME6	8
BP	GO:0048333	mesodermal cell differentiation	8/2159	35/18670	0.04288	0.3857	0.3573	HOXA11/ITGB3/ITGA2/FGFR2/FOXC2/HMGA2/FGFR1/FOXF1	8
BP	GO:0044262	cellular carbohydrate metabolic process	43/2159	286/18670	0.04319	0.3857	0.3573	GPD2/NUPR1/IDH1/RBKS/SYNJ2/B3GNT9/HK1/ACACB/FGGY/PDK2/B3GNT2/NFE2L1/ENOSF1/SESN2/PMAIP1/PPP1R3E/SLC5A3/B4GALT5/GNE/PPIP5K1/FOXK2/PCK2/IMPA1/AOAH/PPIP5K2/COX11/ABHD10/ENPP1/HAS1/HS2ST1/CSGALNACT2/IMPAD1/SLC35B4/PHKB/INPP5B/EXT1/COQ3/EXTL2/HK2/MTMR7/PHKA1/CRY1/IGF1	43
BP	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	7/2159	29/18670	0.0434	0.3857	0.3573	CDKN1C/ADAM17/RNF111/TGFB1I1/GIPC1/SNW1/CDKN2B	7
BP	GO:0051642	centrosome localization	7/2159	29/18670	0.0434	0.3857	0.3573	FHOD1/PARD3/GPSM2/KIF5B/MISP/NIN/BICD2	7
BP	GO:0070229	negative regulation of lymphocyte apoptotic process	7/2159	29/18670	0.0434	0.3857	0.3573	TSC22D3/FOXP1/ARG2/CD27/BCL6/ADA/SLC39A10	7
BP	GO:0090162	establishment of epithelial cell polarity	7/2159	29/18670	0.0434	0.3857	0.3573	HES1/ARF6/PARD3/SIPA1L3/GOLPH3/FRMD4A/FOXF1	7
BP	GO:1900027	regulation of ruffle assembly	7/2159	29/18670	0.0434	0.3857	0.3573	ICAM1/CAV1/SH3YL1/RHOG/EVL/PFN2/HRAS	7
BP	GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus	7/2159	29/18670	0.0434	0.3857	0.3573	CDKN1C/ADAM17/RNF111/TGFB1I1/GIPC1/SNW1/CDKN2B	7
BP	GO:2000036	regulation of stem cell population maintenance	7/2159	29/18670	0.0434	0.3857	0.3573	LBH/ELAVL1/HMGA2/YAP1/TP63/REST/ZC3H13	7
BP	GO:2000515	negative regulation of CD4-positive, alpha-beta T cell activation	7/2159	29/18670	0.0434	0.3857	0.3573	IL4R/CBFB/CD274/ARG2/SOCS5/BCL6/SMAD7	7
BP	GO:0014855	striated muscle cell proliferation	15/2159	81/18670	0.04341	0.3857	0.3573	SIX1/CCNB1/CFLAR/AKIRIN1/HEY2/RBPJ/FGFR2/FOXC2/PRKAR1A/YAP1/JAK2/FGFR1/NOTCH1/PAXBP1/TBX2	15
BP	GO:0048708	astrocyte differentiation	15/2159	81/18670	0.04341	0.3857	0.3573	BMP2/ABL1/LIF/HES1/CLCF1/SOX8/ID2/MAP2K1/NKX2-2/TLR4/IFNG/NOTCH1/ROR2/EPHA4/CDK6	15
BP	GO:0034219	carbohydrate transmembrane transport	20/2159	116/18670	0.04372	0.3875	0.359	GRB10/SLC2A10/APPL2/YES1/SESN2/SLC5A3/SLC2A11/TMEM144/C2CD5/SLC2A3/NR4A3/ENPP1/PRKCI/SLC50A1/SLC45A1/SLC23A2/RHOQ/HK2/TSC1/IGF1	20
BP	GO:0030111	regulation of Wnt signaling pathway	53/2159	363/18670	0.04387	0.3875	0.359	BMP2/DDX3X/MKS1/ABL1/CBFB/TBX18/EGR1/MACF1/JADE1/DDIT3/GRB10/SCYL2/CAV1/WWTR1/PSME4/TLE3/SMURF2/NFKB1/TCF7L2/GSKIP/KLHL12/PSMC2/DVL3/CTNND2/SPIN1/FZD1/DVL2/TBL1XR1/RBPJ/CBY1/FGFR2/TIAM1/GSC/SHISA2/CUL3/FOXL1/PSMD4/YAP1/CSNK1E/CCAR2/TNFAIP3/NKD2/NOTCH1/ROR2/DCDC2/SMARCA4/IGFBP1/ZRANB1/HMGXB4/DAAM2/NLK/KREMEN2/PFDN5	53
BP	GO:0001890	placenta development	25/2159	152/18670	0.04389	0.3875	0.359	FOSL1/RBM15/LIF/HES1/NDP/CDKN1C/GJB2/CDKN1B/EPAS1/NR2F2/MAP2K1/HEY2/STOX2/ADA/SOCS3/PTK2/RBPJ/FGFR2/EOMES/CEBPA/ZFAT/HSF1/JUNB/VDR/BIRC2	25
BP	GO:0006767	water-soluble vitamin metabolic process	16/2159	88/18670	0.04389	0.3875	0.359	PNPO/MCCC1/GSTO1/MMAB/GSTO2/PCCB/SLC19A2/SLC2A3/AKR1A1/ENPP1/RFK/SLC23A2/ACPP/SLC25A32/SLC46A1/SLC52A2	16
BP	GO:0050810	regulation of steroid biosynthetic process	17/2159	95/18670	0.04412	0.3875	0.359	BMP2/SREBF1/EGR1/FGF1/ACACB/NFKB1/MVK/ELOVL6/SP1/IFNG/CLCN2/GPAM/REST/VDR/FDFT1/POR/MVD	17
BP	GO:0097711	ciliary basal body-plasma membrane docking	17/2159	95/18670	0.04412	0.3875	0.359	MKS1/B9D1/ODF2/RAB11A/TUBB4B/HAUS5/CEP70/CEP57/MAPRE1/HAUS6/CSNK1E/TUBA4A/CC2D2A/PRKACA/CEP89/SDCCAG8/HAUS3	17
BP	GO:1903076	regulation of protein localization to plasma membrane	17/2159	95/18670	0.04412	0.3875	0.359	MMP14/ARF6/EPHA2/RAB11FIP2/VPS4A/RHOG/STAC/RAB11A/PRKCI/KIF5B/BCL2L1/IFNG/NKD2/AP2M1/RHOQ/EPHB2/PICALM	17
BP	GO:0051495	positive regulation of cytoskeleton organization	35/2159	226/18670	0.04413	0.3875	0.359	ABL1/ICAM1/ARF6/FHOD1/JMY/F2RL1/CDKN1B/RHOBTB1/ARPC5L/BCAS3/ARPC5/GMFB/FMN2/SDC4/GPSM2/EVL/ARPC2/MYO1C/FCHSD2/MAPRE1/CDK5R1/RICTOR/PFN2/ARPC4/CEP120/VASP/RHOC/WDR1/PPM1F/SH3PXD2B/WASL/CDC42EP2/NIN/HRAS/TSC1	35
BP	GO:0045604	regulation of epidermal cell differentiation	12/2159	61/18670	0.04456	0.3902	0.3615	MAFF/CBFB/HES1/HOXA7/HEY2/SGPP1/ERRFI1/MAFG/TP63/NOTCH1/VDR/TRIM16	12
BP	GO:0050701	interleukin-1 secretion	12/2159	61/18670	0.04456	0.3902	0.3615	FOXP1/RIPK2/ARG2/HK1/F2RL1/PANX1/SERPINB1/AIM2/TNFAIP3/TLR4/CPTP/TRIM16	12
BP	GO:0055023	positive regulation of cardiac muscle tissue growth	10/2159	48/18670	0.04514	0.3937	0.3647	CCNB1/PARP2/HEY2/RBPJ/FGFR2/YAP1/FGFR1/NOTCH1/TBX2/IGF1	10
BP	GO:1902905	positive regulation of supramolecular fiber organization	32/2159	204/18670	0.04515	0.3937	0.3647	ABL1/ICAM1/ARF6/FHOD1/JMY/F2RL1/CDKN1B/RHOBTB1/ARPC5L/ARPC5/GMFB/FMN2/SDC4/EVL/ARPC2/MYO1C/FCHSD2/MAPRE1/CDK5R1/RICTOR/PFN2/ARPC4/RB1/VASP/RHOC/WDR1/PPM1F/SH3PXD2B/WASL/CDC42EP2/NIN/TSC1	32
BP	GO:0019318	hexose metabolic process	38/2159	249/18670	0.04516	0.3937	0.3647	GPD2/ALDH5A1/HK1/ACACB/PDK2/FUT4/NFE2L1/DCXR/SESN2/PMAIP1/PPP1R3E/FPGT/FOXK2/PCK2/GALM/FUT8/AKR1A1/PKM/COX11/ENPP1/ADPGK/SLC37A4/PFKP/SLC35B4/GDPGP1/OMA1/DLAT/CHST15/SLC35A2/HK2/MAN2A1/PFKM/PMM1/CREM/NISCH/PIK3CA/CRY1/IGF1	38
BP	GO:0009952	anterior/posterior pattern specification	34/2159	219/18670	0.04533	0.3946	0.3656	MEOX1/BMP2/TBX18/HOXA11/HOXA10/LDB1/HOXD8/DDIT3/HES1/HOXA7/HOXA5/OTX1/MESP2/HES4/HOXA6/HIPK1/ACVR2A/NR2F2/HEY2/SCMH1/RBPJ/FOXC2/EMX2/TSHZ1/NOTCH1/ROR2/PBX1/HOXA3/TIFAB/CRKL/FOXF1/HOXA2/HOXD4/HOXC10	34
BP	GO:0009166	nucleotide catabolic process	29/2159	182/18670	0.04582	0.3983	0.3691	HDDC3/ZBTB7A/NT5E/NUPR1/NUDT18/ACOT7/HK1/PRKAG1/RAE1/FOXK2/ADA/PDE4D/PNP/AMPD3/PKM/ADPGK/PFKP/NUP35/DNPH1/IFNG/SEH1L/NUP98/HK2/NUP153/PFKM/NUDT17/DERA/NUDT11/IGF1	29
BP	GO:0016239	positive regulation of macroautophagy	13/2159	68/18670	0.04604	0.3991	0.3697	ULK1/RIPK2/LRSAM1/EPM2A/SESN2/RALB/SESN3/IRGM/SPTLC2/PIP4K2A/GNAI3/TRIM13/TSC1	13
BP	GO:0071230	cellular response to amino acid stimulus	13/2159	68/18670	0.04604	0.3991	0.3697	SIX1/DNMT1/DNMT3A/SESN2/SESN3/LAMTOR3/LAMTOR4/BCL2L1/UBR1/HSF1/CPEB1/FYN/RRAGC	13
BP	GO:0002221	pattern recognition receptor signaling pathway	31/2159	197/18670	0.04631	0.4008	0.3714	BIRC3/MAP2K6/IKBKE/NLRX1/TANK/TNIP1/NFKBIL1/RIPK2/CAV1/OTUD4/TRIL/IRF3/TAB3/RAB11FIP2/APPL2/PELI1/F2RL1/RELA/RPS6KA3/PJA2/CHUK/TRAF3/IRAK4/UBE2N/TNFAIP3/IRGM/TLR4/LRRC19/IRAK2/FLOT1/BIRC2	31
BP	GO:0019751	polyol metabolic process	21/2159	124/18670	0.0467	0.4036	0.3739	MINPP1/GPD2/SYNJ2/GCH1/SLC5A3/PPIP5K1/SGPP1/PCK2/PLCB1/SPHK1/IMPA1/PCBD2/PPIP5K2/IMPAD1/SPTLC2/INPP5B/COQ3/QDPR/MTMR7/GALR2/NUDT11	21
BP	GO:0120032	regulation of plasma membrane bounded cell projection assembly	28/2159	175/18670	0.0469	0.4047	0.375	ATP8B1/MNS1/ICAM1/ARF6/SLIT2/CAV1/EPHA2/AKIRIN1/F2RL1/IFT88/BCAS3/DPYSL3/SH3YL1/RHOG/FRMD7/EVL/ARPC2/PFN2/SRGAP2C/CEP120/DNM3/RHOQ/KLF5/DCDC2/WASL/CDC42EP2/HRAS/SDCCAG8	28
BP	GO:0001707	mesoderm formation	14/2159	75/18670	0.04704	0.4047	0.375	HOXA11/ITGB3/ITGA2/EPHA2/MESP2/FGFR2/EOMES/FOXC2/HMGA2/NR4A3/PRKAR1A/FGFR1/FOXF1/PRKACA	14
BP	GO:0002200	somatic diversification of immune receptors	14/2159	75/18670	0.04704	0.4047	0.375	CLCF1/PARP3/PAXIP1/POLL/BCL6/POLB/MLH1/TP53BP1/HMGB2/IL27RA/CTNNBL1/PMS2P3/PMS2P1/LIG4	14
BP	GO:0010508	positive regulation of autophagy	20/2159	117/18670	0.04722	0.4047	0.375	ULK1/RIPK2/LRSAM1/PLEKHF1/PRKD1/EPM2A/SESN2/RALB/SESN3/CAMKK2/IRGM/MID2/SPTLC2/PIP4K2A/IFNG/MTDH/HK2/GNAI3/TRIM13/TSC1	20
BP	GO:0022904	respiratory electron transport chain	20/2159	117/18670	0.04722	0.4047	0.375	GPD2/CCNB1/ETFB/SLC25A22/ALDH5A1/NDUFV2/COX15/BID/NDUFA6/NDUFB5/COX1/MYBBP1A/NDUFS3/UQCR10/NDUFV1/NDUFS2/ISCU/NDUFB10/NDUFA11/D2HGDH	20
BP	GO:0032970	regulation of actin filament-based process	56/2159	388/18670	0.04723	0.4047	0.375	ABL1/VILL/ARHGAP28/ICAM1/ABRACL/ARF6/RGS4/SLIT2/FHOD1/CAV1/TMOD2/CXCL12/JMY/F2RL1/RHOBTB1/ARPC5L/BCAS3/SLC9A1/ARHGDIA/ARPC5/PDE4D/GMFB/RHOG/FMN2/CNN2/SDC4/FRMD7/PFN4/EVL/ARPC2/MYO1C/MLST8/FCHSD2/CDK5R1/RICTOR/ECT2/PFN2/ARPC4/PDPN/VASP/PDGFRB/TMOD3/RHOQ/TRIOBP/RHOC/PREX1/WDR1/PPM1F/SH3PXD2B/WASL/RASA1/CDC42EP2/SPTA1/HRAS/PHLDB2/TSC1	56
BP	GO:0017145	stem cell division	9/2159	42/18670	0.04763	0.4068	0.3769	LBH/AKNA/WWTR1/DOCK7/ETV5/FGFR2/CUL3/FGFR1/NOTCH1	9
BP	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	9/2159	42/18670	0.04763	0.4068	0.3769	PAN2/PAN3/DIS3L/EXOSC8/CNOT6L/PARN/CNOT6/EXOSC4/EXOSC10	9
BP	GO:0060415	muscle tissue morphogenesis	15/2159	82/18670	0.04767	0.4068	0.3769	BMP2/FZD2/PTCD2/UBE4B/MYOM2/HEY2/FZD1/RBPJ/FGFR2/FOXC2/ACTC1/SMAD7/NOTCH1/ANKRD1/ADARB1	15
BP	GO:0006383	transcription by RNA polymerase III	11/2159	55/18670	0.04779	0.4072	0.3773	ZNF143/ZC3H8/BRF2/POLR3K/POLR1C/PRDX5/ELL/POLR3C/CEBPA/NAB2/ICE2	11
BP	GO:1990823	response to leukemia inhibitory factor	17/2159	96/18670	0.04806	0.4084	0.3784	SPRY2/GFPT2/ICAM1/B3GNT2/TNFSF11/BCAT2/SOCS3/GNPNAT1/SNX10/PARP16/PFKP/NUP35/SMAD7/KLF5/HK2/PMM1/VEGFC	17
BP	GO:1990830	cellular response to leukemia inhibitory factor	17/2159	96/18670	0.04806	0.4084	0.3784	SPRY2/GFPT2/ICAM1/B3GNT2/TNFSF11/BCAT2/SOCS3/GNPNAT1/SNX10/PARP16/PFKP/NUP35/SMAD7/KLF5/HK2/PMM1/VEGFC	17
BP	GO:0050770	regulation of axonogenesis	29/2159	183/18670	0.04866	0.4091	0.379	ABL1/MACF1/EPHB3/ADNP/ZSWIM6/SLIT2/CXCL12/WDR36/IFRD1/ARHGDIA/MAP2K1/SIPA1L1/RAB11A/PTK2/TIAM1/BDNF/SEMA7A/GDI1/TNFRSF12A/CDK5R1/LINGO1/RYK/EPHB2/SEMA4G/ZFYVE27/EPHA4/MYCBP2/NIN/TTL	29
BP	GO:0031333	negative regulation of protein complex assembly	23/2159	139/18670	0.04868	0.4091	0.379	DDX3X/VILL/ULK1/SLIT2/TMOD2/LMO4/PRKCZ/HEY2/KIF14/NLRC3/PFN4/MAPRE1/PFN2/CPTP/IMPACT/TMOD3/THRA/TRIOBP/STYXL1/BIRC2/SPTA1/STXBP1/TFIP11	23
BP	GO:0007221	positive regulation of transcription of Notch receptor target	5/2159	18/18670	0.04869	0.4091	0.379	RBM15/RBPJ/SNW1/NOTCH1/PBX1	5
BP	GO:0016446	somatic hypermutation of immunoglobulin genes	5/2159	18/18670	0.04869	0.4091	0.379	POLL/POLB/MLH1/PMS2P3/PMS2P1	5
BP	GO:0031065	positive regulation of histone deacetylation	5/2159	18/18670	0.04869	0.4091	0.379	SREBF1/PRKD1/BCL6/C6orf89/AKAP8	5
BP	GO:0046459	short-chain fatty acid metabolic process	5/2159	18/18670	0.04869	0.4091	0.379	ALDH5A1/PCCB/PCK2/MCEE/THNSL2	5
BP	GO:0060749	mammary gland alveolus development	5/2159	18/18670	0.04869	0.4091	0.379	CCND1/HOXA5/TNFSF11/ID2/FOXF1	5
BP	GO:0061377	mammary gland lobule development	5/2159	18/18670	0.04869	0.4091	0.379	CCND1/HOXA5/TNFSF11/ID2/FOXF1	5
BP	GO:0051054	positive regulation of DNA metabolic process	35/2159	228/18670	0.04914	0.4123	0.382	DBF4/JUN/ERCC6/ATF7IP/DNMT1/OTUD4/CLCF1/PARP3/PAXIP1/NVL/UCN/MAPKAPK5/RAD50/EREG/MLH1/FMN2/PARN/KCTD13/SETDB1/TP53BP1/UBE2N/ZNF304/BABAM1/DDX11/FGFR1/PDGFRB/POT1/HSF1/ST20/ATF1/EYA4/NAF1/CDC7/HRAS/WRN	35
BP	GO:0048568	embryonic organ development	61/2159	428/18670	0.04922	0.4124	0.3821	SIX1/MKS1/SPRY2/LIF/OSR2/MMP14/HOXA11/IFT172/HES1/FZD2/HOXA1/EPHA2/CDKN1C/HOXA7/RDH10/HOXA5/OTX1/EPAS1/ARL13B/HOXA6/HIPK1/NR2F2/ID2/MAP2K1/HEY2/ADA/SATB2/SOCS3/DVL2/RBPJ/FGFR2/EOMES/PHACTR4/FOXC2/NR4A3/GSC/SH2B3/LRIG3/YAP1/TSHZ1/FGFR1/CEBPA/NOTCH1/ID3/ZFAT/IFT52/HSF1/EPHB2/TRIOBP/ROR2/PBX1/JUNB/HOXA3/SEC24B/TIFAB/FOXF1/TBX2/GJB6/CC2D2A/HOXA2/HOXD4	61
BP	GO:0032835	glomerulus development	12/2159	62/18670	0.04968	0.4152	0.3847	EGR1/CFLAR/HES1/JAG1/WWTR1/FOXC2/MAGI2/MPV17/NOTCH1/CD24/PDGFRB/AGTR2	12
BP	GO:0034314	Arp2/3 complex-mediated actin nucleation	8/2159	36/18670	0.04976	0.4152	0.3847	JMY/ARPC5L/ARPC5/GMFB/ARPC2/FCHSD2/ARPC4/WASL	8
BP	GO:0060428	lung epithelium development	8/2159	36/18670	0.04976	0.4152	0.3847	HOXA5/FGF7/MAP2K1/RBPJ/FGFR2/ERRFI1/YAP1/THRA	8
BP	GO:0006090	pyruvate metabolic process	25/2159	154/18670	0.05009	0.4174	0.3867	ZBTB7A/NUPR1/PDP2/HK1/GSTZ1/PRKAG1/PDK2/RAE1/FOXK2/PCK2/PKM/NR4A3/ADPGK/PFKP/NUP35/IFNG/SEH1L/DLAT/NUP98/HK2/NUP153/PFKM/PDP1/HOGA1/IGF1	25
BP	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	21/2159	125/18670	0.05025	0.4177	0.387	CCND1/CCNB1/JADE1/SLFN11/CDK4/RFWD3/CDKN1B/CDKN2D/PCBP4/CNOT6L/RPA2/CDKN2C/CNOT6/TFDP2/MUC1/GADD45A/RB1/E2F4/CDC25C/CDKN2B/CDK6	21
BP	GO:0071478	cellular response to radiation	30/2159	191/18670	0.05033	0.4177	0.387	TANK/ZBTB1/EGR1/AQP1/GPR88/HMGA2/ELK1/TP53BP1/CASP9/YAP1/ECT2/PPEF1/GADD45A/BCL2L1/IMPACT/HSF1/C9orf116/ST20/E2F4/SDE2/RAD9A/GTF2H5/HRAS/POLE3/LIG4/WRN/CRY1/SWI5/NAMPT/USP28	30
BP	GO:0042471	ear morphogenesis	20/2159	118/18670	0.05093	0.4177	0.387	SIX1/SPRY2/OSR2/FZD2/HOXA1/OTX1/DVL2/FGFR2/NR4A3/GSC/LRIG3/TSHZ1/FGFR1/EPHB2/TRIOBP/ROR2/SEC24B/TIFAB/GJB6/HOXA2	20
BP	GO:0002686	negative regulation of leukocyte migration	10/2159	49/18670	0.05107	0.4177	0.387	DUSP1/SLIT2/CXCL12/HOXA7/ADA/PLCB1/LRCH1/IL27RA/WASL/EMILIN1	10
BP	GO:0030857	negative regulation of epithelial cell differentiation	10/2159	49/18670	0.05107	0.4177	0.387	CCND1/S1PR3/HES1/CAV1/JAG1/HOXA7/YAP1/TP63/IFNG/NOTCH1	10
BP	GO:0045010	actin nucleation	10/2159	49/18670	0.05107	0.4177	0.387	JMY/ARPC5L/ARPC5/GMFB/FMN2/EVL/ARPC2/FCHSD2/ARPC4/WASL	10
BP	GO:0097300	programmed necrotic cell death	10/2159	49/18670	0.05107	0.4177	0.387	BIRC3/CFLAR/CAV1/IRF3/PELI1/PPIF/MAP3K5/TLR4/BIRC2/SLC25A4	10
BP	GO:0010586	miRNA metabolic process	7/2159	30/18670	0.05116	0.4177	0.387	AGO2/NFKB1/RELA/BCDIN3D/DROSHA/PARN/HRAS	7
BP	GO:0090200	positive regulation of release of cytochrome c from mitochondria	7/2159	30/18670	0.05116	0.4177	0.387	BID/PMAIP1/PPIF/PDCD5/PLAUR/TNFSF10/MLLT11	7
BP	GO:0014706	striated muscle tissue development	56/2159	390/18670	0.05118	0.4177	0.387	FOS/SIX1/BMP2/MAFF/SGCD/HIVEP3/EGR1/NUPR1/CCNB1/CFLAR/EGR2/PARP2/RGS4/NR1D2/PTCD2/CAV1/NDUFV2/UBE4B/AKIRIN1/MYOM2/HOMER1/HLF/BCL9L/SOX8/NR2F2/ID2/SLC9A1/IFRD1/HEY2/MEF2D/RBPJ/CBY1/FGFR2/EOMES/FOXC2/ACTC1/MYL6B/PRKAR1A/YAP1/RGS2/FGFR1/FOXN2/RB1/SMAD7/NOTCH1/PDGFRB/AGTR2/KLF5/FLOT1/MYOZ2/PDLIM5/ANKRD1/TBX2/DDX5/TSC1/IGF1	56
BP	GO:0001783	B cell apoptotic process	6/2159	24/18670	0.05121	0.4177	0.387	FOXP1/TRAF3IP2/BCL6/ADA/SLC39A10/CRKL	6
BP	GO:0032925	regulation of activin receptor signaling pathway	6/2159	24/18670	0.05121	0.4177	0.387	LEMD3/FST/ACVR2A/MAGI2/FSTL3/SMAD7	6
BP	GO:0034629	cellular protein-containing complex localization	6/2159	24/18670	0.05121	0.4177	0.387	SGCD/RALB/SNAPIN/SMAD7/SEH1L/WASL	6
BP	GO:0071218	cellular response to misfolded protein	6/2159	24/18670	0.05121	0.4177	0.387	RNF185/TOR1A/KLHL15/CUL3/ATXN3/DNAJB14	6
BP	GO:0099563	modification of synaptic structure	6/2159	24/18670	0.05121	0.4177	0.387	ABL1/TIAM1/PFN2/REST/EPHA4/DLGAP3	6
BP	GO:0016049	cell growth	68/2159	484/18670	0.05123	0.4177	0.387	BDKRB1/DDX3X/ABL1/ULK1/MACF1/MMP14/ADNP/JADE1/DCBLD2/PARP2/RGS4/SLIT2/CRLF3/CXCL12/TMEM97/CDKN1B/UCN/SESN2/CDKN2D/PRKCZ/WDR36/BCL6/RPS6KA3/SLC9A1/IFRD1/ADAM17/HBEGF/RAB11A/SPHK1/NDRG3/CDKN2C/KIF14/TIAM1/BDNF/SEMA7A/ING1/SERTAD3/GDI1/ENPP1/TNFRSF12A/CDK5R1/RYK/CCAR2/CPNE1/RGS2/RB1/DNPH1/IMPACT/AGTR2/BLZF1/ATAD3A/NDUFS3/ST20/SMARCA4/IGFBP1/SEMA4G/FLRT1/OGFR/NME6/CRKL/ZFYVE27/EBAG9/PDLIM5/EXOSC4/NIN/TTL/SIPA1/IGF1	68
BP	GO:1903509	liposaccharide metabolic process	19/2159	111/18670	0.0515	0.4193	0.3885	ST3GAL2/B4GALT3/MPPE1/ALDH5A1/PIGC/PGAP2/GLTP/B4GALT5/NEU1/AOAH/B4GALT6/CPTP/PIGB/GBGT1/PIGV/PGAP3/SUMF2/CLN3/CREM	19
BP	GO:0050000	chromosome localization	14/2159	76/18670	0.05178	0.4204	0.3895	CCNB1/CHMP7/GEM/VPS4A/MLH1/RAB11A/FMN2/KIF14/CUL3/SEH1L/MIS12/NUP98/KIF2B/TTL	14
BP	GO:0007179	transforming growth factor beta receptor signaling pathway	31/2159	199/18670	0.05191	0.4204	0.3895	FOS/ZBTB7A/JUN/GDF5/CAV1/NRROS/LEMD3/CDKN1C/SMURF2/APPL2/PRKCZ/BCL9L/PARD3/ACVR2A/ADAM17/RNF111/PTK2/TGFB1I1/FUT8/ZYX/GIPC1/NREP/FURIN/SNW1/PRDM16/SMAD7/GLG1/CDKN2B/NLK/EMILIN1/SMAD9	31
BP	GO:0016052	carbohydrate catabolic process	31/2159	199/18670	0.05191	0.4204	0.3895	GPD2/ZBTB7A/NUPR1/RBKS/HK1/PRKAG1/FUT4/DCXR/ENOSF1/RAE1/FOXK2/GALM/NEU1/FUT8/AOAH/AKR1A1/PKM/ABHD10/ADPGK/PFKP/NUP35/PHKB/IFNG/SEH1L/NUP98/HK2/NUP153/PFKM/PHKA1/DERA/IGF1	31
BP	GO:0035966	response to topologically incorrect protein	31/2159	199/18670	0.05191	0.4204	0.3895	EDEM3/CCND1/CREB3L4/DDIT3/HSPH1/CDK5RAP3/RNF185/VAPB/TOR1A/CALR3/DAXX/ATF6B/DNAJB5/FBXO6/TATDN2/SHC1/KLHL15/HSPE1/PARP16/CUL3/DDX11/ATXN3/TMEM33/HSPB1/DNAJB14/HSF1/EXTL2/IGFBP1/JKAMP/TOR1B/MANF	31
BP	GO:1901214	regulation of neuron death	46/2159	313/18670	0.0521	0.4213	0.3904	FOS/SIX1/TNFRSF1B/ABL1/JUN/EGR1/NUPR1/ADNP/GDF5/DDIT3/PARP2/MCL1/CLCF1/DAXX/UCN/EGLN3/FZD1/MAP3K5/KIF14/ELK1/NR4A3/BDNF/CASP9/PRKCI/CDK5R1/JAK2/NAE1/ATP13A2/BCL2L1/TLR4/IFNG/LANCL1/HSF1/ZPR1/NR4A2/STAMBP/PICALM/REST/FYN/RASA1/CLN3/HRAS/PIK3CA/STXBP1/LIG4/TSC1	46
BP	GO:2001022	positive regulation of response to DNA damage stimulus	17/2159	97/18670	0.05225	0.422	0.391	SPRED1/ERCC6/PARP3/PAXIP1/PMAIP1/SPRED2/FMN2/HMGA2/NSMCE1/UBE2N/BABAM1/DDX11/CCAR2/RAD9A/EYA4/ANKRD1/DDX5	17
BP	GO:0006470	protein dephosphorylation	47/2159	321/18670	0.05279	0.4251	0.3939	DUSP6/PPP2R2A/DUSP1/DUSP5/MINPP1/PDP2/BOD1L2/RNGTT/DUSP3/PTPMT1/PPP1R3E/MTMR3/FAM220A/PTPN12/PPP1R14C/PPM1H/PPM1B/DUSP7/PHACTR4/MAGI2/DUSP28/PPP6R1/PPME1/PPP2CB/JAK2/PPEF1/SBF1/PPP4R4/SLC39A10/UBASH3B/PDGFRB/AGTR2/PPTC7/PPM1F/STYXL1/DUSP27/EYA4/MTMR7/RPRD1A/CDC25C/MGAT5/PPP3CC/DUSP19/CTTNBP2NL/PDP1/TSC1/PPM1G	47
BP	GO:0060491	regulation of cell projection assembly	28/2159	177/18670	0.05294	0.4251	0.3939	ATP8B1/MNS1/ICAM1/ARF6/SLIT2/CAV1/EPHA2/AKIRIN1/F2RL1/IFT88/BCAS3/DPYSL3/SH3YL1/RHOG/FRMD7/EVL/ARPC2/PFN2/SRGAP2C/CEP120/DNM3/RHOQ/KLF5/DCDC2/WASL/CDC42EP2/HRAS/SDCCAG8	28
BP	GO:1902903	regulation of supramolecular fiber organization	51/2159	352/18670	0.05296	0.4251	0.3939	ABL1/VILL/MAP1S/ARHGAP28/ICAM1/ARF6/RGS4/SLIT2/FHOD1/TMOD2/CXCL12/JMY/F2RL1/CDKN1B/RHOBTB1/ARPC5L/SLC9A1/ARPC5/GMFB/FMN2/SDC4/FRMD7/PFN4/EVL/ARPC2/MYO1C/FCHSD2/MAPRE1/CDK5R1/RICTOR/PFN2/ARPC4/RB1/VASP/MID1/TMOD3/MAP1A/TRIOBP/RHOC/PREX1/WDR1/PPM1F/SH3PXD2B/WASL/RASA1/CDC42EP2/SPTA1/NIN/PHLDB2/TSC1/EMILIN1	51
BP	GO:0046148	pigment biosynthetic process	11/2159	56/18670	0.05351	0.4251	0.3939	COX15/SLC25A38/PRPS1/NFE2L1/ALAS1/CTNS/ADA/GIPC1/CPOX/MYO5A/SLC11A2	11
BP	GO:1903078	positive regulation of protein localization to plasma membrane	11/2159	56/18670	0.05351	0.4251	0.3939	ARF6/EPHA2/RAB11FIP2/RHOG/STAC/RAB11A/PRKCI/KIF5B/IFNG/NKD2/EPHB2	11
BP	GO:0007389	pattern specification process	63/2159	446/18670	0.05372	0.4251	0.3939	MEOX1/SIX1/BMP2/MKS1/TBX18/HOXA11/IFT172/HOXA10/LDB1/HOXD8/MNS1/DDIT3/HES1/EGR2/FGF1/HOXA7/HOXA5/OTX1/ARL13B/MESP2/HES4/HOXA6/HIPK1/ACVR2A/NR2F2/HEY2/NKX2-2/SCMH1/SATB2/RNF111/DVL2/RBPJ/FGFR2/EOMES/FOXC2/GSC/EMX2/INTU/GREM2/FBXL15/IFT74/TSHZ1/ARL6/FGFR1/TP63/MID1/NOTCH1/IFT52/C9orf116/ROR2/PBX1/HOXA3/GAS8/TIFAB/CRKL/FOXF1/DAAM2/TBX2/CC2D2A/HOXA2/PRKACA/HOXD4/HOXC10	63
BP	GO:0051258	protein polymerization	42/2159	283/18670	0.0538	0.4251	0.3939	ABL1/VILL/TRIM6/MSRB2/ARHGAP28/ICAM1/DIAPH1/ARF6/SLIT2/TMOD2/JMY/CDKN1B/RHOBTB1/ARPC5L/MAP7D3/ARPC5/GMFB/FMN2/PFN4/EVL/ARPC2/MYO1C/UBE2S/FCHSD2/MAPRE1/CDK5R1/RICTOR/GOLGA2/JAK2/PFN2/ARPC4/ARL6/VASP/TMOD3/TRIOBP/MSRB1/PREX1/WASL/RASA1/CDC42EP2/SPTA1/NIN	42
BP	GO:0002829	negative regulation of type 2 immune response	4/2159	13/18670	0.05419	0.4251	0.3939	ARG2/SOCS5/BCL6/IL27RA	4
BP	GO:0030656	regulation of vitamin metabolic process	4/2159	13/18670	0.05419	0.4251	0.3939	RDH10/NFKB1/IFNG/VDR	4
BP	GO:0035627	ceramide transport	4/2159	13/18670	0.05419	0.4251	0.3939	GLTP/PLEKHA3/SGPP1/CPTP	4
BP	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein	4/2159	13/18670	0.05419	0.4251	0.3939	CAV1/SOCS3/SH2B3/INPP5F	4
BP	GO:0043247	telomere maintenance in response to DNA damage	4/2159	13/18670	0.05419	0.4251	0.3939	DCLRE1A/APEX1/TERF2IP/TFIP11	4
BP	GO:0048715	negative regulation of oligodendrocyte differentiation	4/2159	13/18670	0.05419	0.4251	0.3939	HES1/ID2/NOTCH1/DAAM2	4
BP	GO:0050872	white fat cell differentiation	4/2159	13/18670	0.05419	0.4251	0.3939	TBL1XR1/AACS/PRDM16/CEBPA	4
BP	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain	4/2159	13/18670	0.05419	0.4251	0.3939	ITGA2/CXCL12/TRPA1/FYN	4
BP	GO:0061000	negative regulation of dendritic spine development	4/2159	13/18670	0.05419	0.4251	0.3939	ASAP1/SRGAP2C/DNM3/HDAC2	4
BP	GO:0070986	left/right axis specification	4/2159	13/18670	0.05419	0.4251	0.3939	IFT172/MNS1/ARL13B/NOTCH1	4
BP	GO:0071285	cellular response to lithium ion	4/2159	13/18670	0.05419	0.4251	0.3939	CDKN1B/ID2/CEBPA/LIG4	4
BP	GO:0090179	planar cell polarity pathway involved in neural tube closure	4/2159	13/18670	0.05419	0.4251	0.3939	FZD2/DVL3/FZD1/DVL2	4
BP	GO:0106074	aminoacyl-tRNA metabolism involved in translational fidelity	4/2159	13/18670	0.05419	0.4251	0.3939	VARS2/DTD1/LARS2/PRORSD1P	4
BP	GO:1900225	regulation of NLRP3 inflammasome complex assembly	4/2159	13/18670	0.05419	0.4251	0.3939	NLRC3/TLR4/CPTP/DHX33	4
BP	GO:1902947	regulation of tau-protein kinase activity	4/2159	13/18670	0.05419	0.4251	0.3939	EGR1/RB1/IFNG/NAB2	4
BP	GO:0006403	RNA localization	35/2159	230/18670	0.05456	0.4267	0.3953	NPIPA1/ZNF593/ALKBH5/U2AF1L4/RAE1/SNUPN/THOC6/PARN/AGFG1/ZNHIT6/MYO1C/AHCTF1/UPF2/EIF4E/DDX39A/NUP35/NOP10/XPO1/DDX19B/SEH1L/PRPF6/HSF1/SRSF11/UPF3B/BICD1/FLOT1/NUP98/NAF1/NUP153/NXT1/PCID2/BICD2/TSC1/RFTN2/EXOSC10	35
BP	GO:0035107	appendage morphogenesis	24/2159	148/18670	0.0546	0.4267	0.3953	MKS1/OSR2/HOXA11/HOXA10/GDF5/B9D1/RDH10/FGFR2/INTU/FGFR1/IMPAD1/TP63/NOTCH1/IFT52/ECE1/ROR2/PBX1/GNA12/TMEM231/HDAC2/TBX2/ZNF141/FRAS1/HOXC10	24
BP	GO:0035108	limb morphogenesis	24/2159	148/18670	0.0546	0.4267	0.3953	MKS1/OSR2/HOXA11/HOXA10/GDF5/B9D1/RDH10/FGFR2/INTU/FGFR1/IMPAD1/TP63/NOTCH1/IFT52/ECE1/ROR2/PBX1/GNA12/TMEM231/HDAC2/TBX2/ZNF141/FRAS1/HOXC10	24
BP	GO:0046328	regulation of JNK cascade	29/2159	185/18670	0.05473	0.4271	0.3957	HIPK3/MAP4K4/GADD45G/ERCC6/RIPK2/IL1RN/CD27/DUSP3/F2RL1/TNFSF11/DAXX/PJA2/DVL3/PLCB1/MAP4K5/DVL2/ZNF622/MAP3K5/TIAM1/GADD45A/GADD45B/TLR4/IL36RN/ROR2/DTNBP1/DUSP19/EPHA4/HRAS/IL36B	29
BP	GO:0002065	columnar/cuboidal epithelial cell differentiation	19/2159	112/18670	0.05557	0.4322	0.4004	BMP2/ABL1/HES1/JAG1/B9D1/HOXA5/SLC4A7/HEY2/NKX2-2/RBPJ/FGFR2/FGFR1/TP63/NOTCH1/TRIOBP/KLF5/TMEM231/SEC24B/CDK6	19
BP	GO:0051817	modification of morphology or physiology of other organism involved in symbiotic interaction	19/2159	112/18670	0.05557	0.4322	0.4004	KPNA2/JUN/TNIP1/FBXL2/VAPB/CHD1/KPNA4/AQP1/F2RL1/SMC3/VAPA/HMGA2/BCL2L1/SP1/SNW1/KPNA1/SMARCA4/REST/CCNT1	19
BP	GO:0051170	import into nucleus	26/2159	163/18670	0.05559	0.4322	0.4004	KPNA2/RBM22/KPNA4/PRKAG1/APPL2/SNUPN/HEATR3/TXNIP/GEMIN8/TNPO3/ECT2/IPO4/HTATIP2/NUP35/IFNG/RAB23/AGTR2/KPNA1/ZPR1/DMAP1/NUP98/NUP153/FAM53C/GEMIN4/NXT1/RANBP6	26
BP	GO:0001738	morphogenesis of a polarized epithelium	23/2159	141/18670	0.05575	0.4328	0.401	MKS1/ABL1/FZD2/PSME4/SMURF2/PSMC2/DVL3/FZD1/DVL2/TIAM1/MAGI2/INTU/PSMD4/RYK/AP2A2/ASTN2/TP63/AP2M1/ROR2/WDR1/SEC24B/FOXF1/EXOC5	23
BP	GO:0010950	positive regulation of endopeptidase activity	28/2159	178/18670	0.05617	0.435	0.403	DDX3X/RIPK2/TNFRSF10A/BID/PMAIP1/CASP4/TNFRSF10B/EGLN3/PDCD5/TNFSF15/MAP3K5/ADRM1/TNFSF10/SEMG2/CASP9/HSPE1/AIM2/JAK2/KHDC1/HSF1/PICALM/ST20/APAF1/PPM1F/REST/FYN/EPHA4/CASC2	28
BP	GO:0033138	positive regulation of peptidyl-serine phosphorylation	18/2159	105/18670	0.0562	0.435	0.403	SPRY2/LIF/TRIM6/ERCC6/RIPK2/CAV1/PRKD1/DOCK7/UCN/FNIP2/IL11/CD44/PFN2/IRGM/IFNG/TERF2IP/SMYD3/PIK3CA	18
BP	GO:0070988	demethylation	13/2159	70/18670	0.05624	0.435	0.403	KDM7A/OTUD4/TET1/ALKBH3/ALKBH5/JMJD6/FTO/APEX1/KDM4A/KDM3B/PPME1/KDM1B/POR	13
BP	GO:0048332	mesoderm morphogenesis	14/2159	77/18670	0.05683	0.438	0.4058	HOXA11/ITGB3/ITGA2/EPHA2/MESP2/FGFR2/EOMES/FOXC2/HMGA2/NR4A3/PRKAR1A/FGFR1/FOXF1/PRKACA	14
BP	GO:0006766	vitamin metabolic process	22/2159	134/18670	0.05686	0.438	0.4058	PNPO/MCCC1/GSTO1/MMAB/GSTO2/RDH10/NFKB1/PCCB/SLC19A2/SLC2A3/AKR1A1/ENPP1/RFK/FGFR1/IFNG/SLC23A2/ACPP/CBR1/SLC25A32/SLC46A1/VDR/SLC52A2	22
BP	GO:0032273	positive regulation of protein polymerization	22/2159	134/18670	0.05686	0.438	0.4058	ICAM1/ARF6/JMY/CDKN1B/RHOBTB1/ARPC5L/ARPC5/GMFB/FMN2/EVL/ARPC2/MYO1C/FCHSD2/MAPRE1/CDK5R1/RICTOR/PFN2/ARPC4/VASP/WASL/CDC42EP2/NIN	22
BP	GO:0007259	JAK-STAT cascade	25/2159	156/18670	0.05691	0.438	0.4058	GHR/LIF/HES1/ERCC6/CRLF3/CAV1/CLCF1/IFNAR2/IFNAR1/DOT1L/SOCS5/SOCS3/SH2B3/JAK2/IL22RA2/INPP5F/IFNG/NOTCH1/HSF1/STAMBP/IL12A/FYN/HDAC2/NMI/IGF1	25
BP	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	15/2159	84/18670	0.05705	0.4385	0.4062	BIRC3/TNFAIP8/DDX3X/CFLAR/CD27/AQP1/CDKN2D/RPS6KA3/PLAUR/CD44/CAAP1/PAK2/PRDX5/BIRC2/POR	15
BP	GO:0003156	regulation of animal organ formation	8/2159	37/18670	0.05731	0.4385	0.4063	SIX1/BMP2/MKS1/HOXA11/HES1/FGF1/FGFR1/NOTCH1	8
BP	GO:1905314	semi-lunar valve development	8/2159	37/18670	0.05731	0.4385	0.4063	TNFRSF1B/SLIT2/JAG1/HEY2/RBPJ/RB1/NOTCH1/EMILIN1	8
BP	GO:0010718	positive regulation of epithelial to mesenchymal transition	10/2159	50/18670	0.0575	0.4385	0.4063	BMP2/JAG1/WWTR1/TCF7L2/BCL9L/TGFB1I1/TIAM1/PDPN/NOTCH1/HDAC2	10
BP	GO:0045540	regulation of cholesterol biosynthetic process	10/2159	50/18670	0.0575	0.4385	0.4063	SREBF1/FGF1/ACACB/MVK/ELOVL6/SP1/GPAM/FDFT1/POR/MVD	10
BP	GO:0060425	lung morphogenesis	10/2159	50/18670	0.0575	0.4385	0.4063	SPRY2/LIF/RDH10/HOXA5/FGF7/MAP2K1/FGFR2/YAP1/SEC24B/FOXF1	10
BP	GO:0106118	regulation of sterol biosynthetic process	10/2159	50/18670	0.0575	0.4385	0.4063	SREBF1/FGF1/ACACB/MVK/ELOVL6/SP1/GPAM/FDFT1/POR/MVD	10
BP	GO:0032869	cellular response to insulin stimulus	33/2159	216/18670	0.05781	0.4403	0.408	ATP2B1/SREBF1/ATP6V1E2/CFLAR/GRB10/CDK4/PDK2/APPL2/RELA/PRKCZ/SESN3/SLC9A1/C2CD5/GKAP1/PCK2/SHC1/SOCS3/FOXC2/PKM/MYO1C/ENPP1/ERRFI1/PRKCI/SP1/ATP6V1B2/RHOQ/CCND3/RAB8B/CPEB1/MYO5A/IGFBP1/PIK3CA/TSC1	33
BP	GO:0006164	purine nucleotide biosynthetic process	44/2159	300/18670	0.05795	0.4404	0.408	ZBTB7A/NUPR1/GCDH/ACOT7/PDP2/HK1/ACACB/GSTZ1/PRKAG1/PDK2/PRPS1/PRPSAP2/IMPDH2/RAE1/PPCDC/ELOVL7/FOXK2/HSD17B8/ADA/PANK1/ELOVL6/AMPD3/PKM/ADPGK/PRPS2/PFKP/NUP35/SLC26A1/IFNG/SEH1L/DLAT/NUP98/HK2/NME5/NME3/NUP153/NME6/PFKM/ELOVL4/PDP1/ACSL4/NPR2/IGF1/PPCS	44
BP	GO:0030308	negative regulation of cell growth	29/2159	186/18670	0.05796	0.4404	0.408	BDKRB1/DDX3X/JADE1/DCBLD2/RGS4/SLIT2/CRLF3/CDKN1B/SESN2/CDKN2D/BCL6/IFRD1/NDRG3/CDKN2C/SEMA7A/ING1/SERTAD3/ENPP1/CDK5R1/RYK/CCAR2/RGS2/AGTR2/NDUFS3/ST20/SMARCA4/SEMA4G/NME6/SIPA1	29
BP	GO:2001056	positive regulation of cysteine-type endopeptidase activity	24/2159	149/18670	0.05823	0.4415	0.409	DDX3X/RIPK2/TNFRSF10A/BID/PMAIP1/CASP4/TNFRSF10B/EGLN3/PDCD5/TNFSF15/MAP3K5/TNFSF10/CASP9/HSPE1/AIM2/JAK2/KHDC1/HSF1/ST20/APAF1/PPM1F/REST/FYN/CASC2	24
BP	GO:0033002	muscle cell proliferation	36/2159	239/18670	0.05861	0.4415	0.409	SIX1/JUN/FOXP1/CCNB1/CFLAR/ITGA2/DNMT1/TRIB1/AKIRIN1/CDKN1B/TCF7L2/ID2/HEY2/HBEGF/EREG/MEF2D/RBPJ/MAP3K5/FGFR2/FOXC2/NR4A3/IRAK4/PRKAR1A/YAP1/JAK2/TNFAIP3/FGFR1/IFNG/NOTCH1/PDGFRB/PAXBP1/IL12A/TBX2/GNAI3/NAMPT/IGF1	36
BP	GO:0051402	neuron apoptotic process	36/2159	239/18670	0.05861	0.4415	0.409	SIX1/JUN/NUPR1/ADNP/GDF5/DDIT3/USP53/MCL1/CLCF1/BID/POLB/EGLN3/KIF14/NR4A3/BDNF/CASP9/PRKCI/CDK5R1/JAK2/NAE1/BCL2L1/TP63/RB1/LANCL1/ZPR1/NR4A2/STAMBP/APAF1/FYN/RASA1/CLN3/HRAS/PIK3CA/STXBP1/LIG4/ADARB1	36
BP	GO:0050678	regulation of epithelial cell proliferation	54/2159	378/18670	0.05897	0.4415	0.409	EGR3/SIX1/BMP2/CCND1/JUN/OSR2/NUPR1/IFT172/GDF5/CFLAR/ITGB3/HES1/FGF1/CAV1/CXCL12/CDKN1C/PRKD1/CDKN1B/HOXA5/TCF7L2/NR2F2/DEAF1/FGF7/ADAM17/EREG/PGF/FGFR2/NLRC3/LIMS2/NR4A3/NRAS/ERRFI1/ZNF304/INTU/YAP1/RICTOR/HMGB2/IFT74/TNFAIP3/FGFR1/SP1/TP63/RB1/NOTCH1/IFT52/CDKN2B/ZNF580/VDR/MAGED1/CDK6/PGR/HRAS/VEGFC/IGF1	54
BP	GO:0009165	nucleotide biosynthetic process	55/2159	386/18670	0.05941	0.4415	0.409	ZBTB7A/NUPR1/GCDH/ACOT7/PDP2/HK1/ACACB/GSTZ1/PRKAG1/PDK2/PRPS1/PRPSAP2/CDADC1/IMPDH2/RAE1/PPCDC/RAD50/ELOVL7/FOXK2/HSD17B8/ADA/LCLAT1/PANK1/ELOVL6/PNP/AMPD3/PKM/ADPGK/PARP16/RFK/PRPS2/PFKP/NUP35/SLC26A1/IFNG/RNLS/SEH1L/DLAT/GPAM/UCK1/NUP98/HK2/NME5/NME3/NUP153/NME6/PFKM/ELOVL4/PDP1/ACSL4/NPR2/DCTD/NAMPT/IGF1/PPCS	55
BP	GO:0003401	axis elongation	7/2159	31/18670	0.05975	0.4415	0.409	SIX1/SPRY2/FGF1/RDH10/FGFR2/MAGI2/YAP1	7
BP	GO:0009154	purine ribonucleotide catabolic process	7/2159	31/18670	0.05975	0.4415	0.409	HDDC3/NT5E/NUDT18/ACOT7/PDE4D/AMPD3/NUDT11	7
BP	GO:0010165	response to X-ray	7/2159	31/18670	0.05975	0.4415	0.409	CCND1/ERCC6/IKBIP/THBD/HMGA2/TP53BP1/LIG4	7
BP	GO:0010543	regulation of platelet activation	7/2159	31/18670	0.05975	0.4415	0.409	TEC/THBD/ABAT/SH2B3/UBASH3B/TLR4/PDPN	7
BP	GO:0021988	olfactory lobe development	7/2159	31/18670	0.05975	0.4415	0.409	SLIT2/ID2/KIF14/EOMES/SEMA7A/ATF5/EXT1	7
BP	GO:0032786	positive regulation of DNA-templated transcription, elongation	7/2159	31/18670	0.05975	0.4415	0.409	ERCC6/CDK12/GTF2F2/SCAF8/ELL/EAPP/CCNT1	7
BP	GO:0033687	osteoblast proliferation	7/2159	31/18670	0.05975	0.4415	0.409	BMP2/ABL1/OSR2/SOX8/FGFR2/JUNB/TMEM119	7
BP	GO:0034661	ncRNA catabolic process	7/2159	31/18670	0.05975	0.4415	0.409	DIS3L/DROSHA/EXOSC8/PARN/PELO/EXOSC4/EXOSC10	7
BP	GO:0043457	regulation of cellular respiration	7/2159	31/18670	0.05975	0.4415	0.409	CCNB1/NOA1/CISD1/IFNG/PRDM16/ISCU/PIK3CA	7
BP	GO:0048710	regulation of astrocyte differentiation	7/2159	31/18670	0.05975	0.4415	0.409	BMP2/LIF/HES1/CLCF1/ID2/NOTCH1/EPHA4	7
BP	GO:1903393	positive regulation of adherens junction organization	7/2159	31/18670	0.05975	0.4415	0.409	ABL1/MAP4K4/ARF6/DUSP3/SDC4/PPM1F/TSC1	7
BP	GO:0002566	somatic diversification of immune receptors via somatic mutation	5/2159	19/18670	0.06	0.4415	0.409	POLL/POLB/MLH1/PMS2P3/PMS2P1	5
BP	GO:0006044	N-acetylglucosamine metabolic process	5/2159	19/18670	0.06	0.4415	0.409	CHST7/CHST2/GNE/GNPNAT1/EXTL2	5
BP	GO:0016074	snoRNA metabolic process	5/2159	19/18670	0.06	0.4415	0.409	PARN/NOP10/NAF1/EXOSC4/EXOSC10	5
BP	GO:0034138	toll-like receptor 3 signaling pathway	5/2159	19/18670	0.06	0.4415	0.409	CAV1/PELI1/F2RL1/TNFAIP3/FLOT1	5
BP	GO:0034312	diol biosynthetic process	5/2159	19/18670	0.06	0.4415	0.409	GCH1/SPHK1/PCBD2/SPTLC2/QDPR	5
BP	GO:0034755	iron ion transmembrane transport	5/2159	19/18670	0.06	0.4415	0.409	SLC39A14/IFNG/ISCU/SLC11A2/SLC25A37	5
BP	GO:0051546	keratinocyte migration	5/2159	19/18670	0.06	0.4415	0.409	MAP4K4/ARF6/KRT16/FGF7/HBEGF	5
BP	GO:0070989	oxidative demethylation	5/2159	19/18670	0.06	0.4415	0.409	TET1/ALKBH3/ALKBH5/JMJD6/FTO	5
BP	GO:1990182	exosomal secretion	5/2159	19/18670	0.06	0.4415	0.409	VPS4A/RAB11A/SDC4/ATP13A2/IFNG	5
BP	GO:2000696	regulation of epithelial cell differentiation involved in kidney development	5/2159	19/18670	0.06	0.4415	0.409	LIF/WWTR1/FAT4/YAP1/CD24	5
BP	GO:0007498	mesoderm development	22/2159	135/18670	0.06082	0.4444	0.4117	HOXA11/LDB1/ITGB3/ITGA2/EPHA2/MEST/MESP2/ACVR2A/FGFR2/EOMES/FOXC2/HMGA2/NR4A3/PRKAR1A/YAP1/JAK2/FGFR1/TP63/EXT1/FOXF1/OVOL1/PRKACA	22
BP	GO:0031069	hair follicle morphogenesis	6/2159	25/18670	0.06104	0.4444	0.4117	TMEM79/FGF7/FGFR2/INTU/TP63/NOTCH1	6
BP	GO:0034035	purine ribonucleoside bisphosphate metabolic process	6/2159	25/18670	0.06104	0.4444	0.4117	HDDC3/ENPP1/SULT4A1/ABHD14B/IMPAD1/SLC26A1	6
BP	GO:0035336	long-chain fatty-acyl-CoA metabolic process	6/2159	25/18670	0.06104	0.4444	0.4117	ACOT7/FAR2/ELOVL7/ELOVL6/ELOVL4/ACSL4	6
BP	GO:0045332	phospholipid translocation	6/2159	25/18670	0.06104	0.4444	0.4117	ATP8B1/TMEM30B/ATP10D/ATP11B/ATP8B3/TMEM30A	6
BP	GO:0046856	phosphatidylinositol dephosphorylation	6/2159	25/18670	0.06104	0.4444	0.4117	SYNJ2/MTMR3/MTMR9/INPP5F/INPP5B/MTMR7	6
BP	GO:0048103	somatic stem cell division	6/2159	25/18670	0.06104	0.4444	0.4117	LBH/AKNA/DOCK7/FGFR2/FGFR1/NOTCH1	6
BP	GO:0072012	glomerulus vasculature development	6/2159	25/18670	0.06104	0.4444	0.4117	EGR1/CFLAR/HES1/FOXC2/NOTCH1/PDGFRB	6
BP	GO:0043297	apical junction assembly	12/2159	64/18670	0.06106	0.4444	0.4117	CBFB/EPHA2/TJP1/PARD3/MPP7/MYO1C/PRKCI/ECT2/MTDH/RHOC/WDR1/PRKACA	12
BP	GO:0048732	gland development	61/2159	434/18670	0.06152	0.4469	0.4141	SIX1/BMP2/CCND1/ABL1/ZBTB1/JUN/EPHB3/CFLAR/ITGA2/HES1/ARF6/LBH/PTCD2/DBP/CAV1/EPHA2/LMO4/CDKN1C/FEM1B/CDKN1B/HOXA5/TNFSF11/RELA/ETV5/POLB/ID2/DEAF1/FGF7/MAP2K1/ADA/PCK2/MPST/RBPJ/GNPNAT1/FGFR2/LIMS2/PKM/HMGCL/CUL3/FSTL3/UPF2/AACS/JAK2/TNFAIP3/FGFR1/TP63/CEBPA/NOTCH1/CLCN2/THRA/PBX1/QDPR/HK2/MAN2A1/HOXA3/CRKL/FOXF1/VDR/TBX2/PGR/PIK3CA	61
BP	GO:0035850	epithelial cell differentiation involved in kidney development	9/2159	44/18670	0.06156	0.4469	0.4141	LIF/JAG1/WWTR1/FOXC2/MAGI2/FAT4/YAP1/NOTCH1/CD24	9
BP	GO:2000117	negative regulation of cysteine-type endopeptidase activity	16/2159	92/18670	0.06189	0.4488	0.4158	BIRC3/TNFAIP8/DDX3X/CFLAR/CD27/AQP1/CDKN2D/RPS6KA3/PLAUR/CD44/CAAP1/PAK2/PRDX5/BIRC2/POR/PCID2	16
BP	GO:0045682	regulation of epidermis development	15/2159	85/18670	0.06219	0.45	0.4169	MAFF/TMEM79/CBFB/HES1/FST/HOXA7/HEY2/SGPP1/ERRFI1/MAFG/TP63/NOTCH1/NAB2/VDR/TRIM16	15
BP	GO:0072028	nephron morphogenesis	14/2159	78/18670	0.06221	0.45	0.4169	SIX1/BMP2/LIF/HOXA11/HES1/FGF1/SOX8/PGF/KLHL3/FAT4/PDGFRB/AGTR2/PBX1/MAGED1	14
BP	GO:0030705	cytoskeleton-dependent intracellular transport	28/2159	180/18670	0.06303	0.4554	0.4219	MAP1S/IFT172/HOOK2/SYBU/IFT88/PRKCZ/HOOK3/COPG2/TTC30B/MYO1C/IFT46/SNAPIN/KIF5B/IFT74/RPGR/HSPB1/MAP1A/IFT52/BICD1/MYO5A/TTC30A/DTNBP1/AP3M2/WASL/CLN3/BICD2/TUBA1B/BLOC1S2	28
BP	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	59/2159	419/18670	0.06318	0.4559	0.4224	EDEM3/UBE2H/CCNB1/ANAPC16/DDIT3/RNF185/FBXO45/FBXL2/ARMC8/CAV1/TRIB1/WWTR1/UBE4B/PSME4/SMURF2/FBXO17/PELI1/FBXO33/ZFAND2B/SOCS5/FBXO6/PSMC2/SPOPL/DET1/ZNRF1/LTN1/TBL1XR1/KIF14/KCTD13/KCTD5/GIPC1/KLHL15/CUL3/UBE2S/PPP2CB/PSMD4/CSNK1E/ATXN3/CCAR2/FBXL15/UBR1/NKD2/SMAD7/CEBPA/DNAJB14/MAP1A/MAN1B1/GNA12/FBXL22/DDA1/TRIB2/TMUB2/KLHL42/BIRC2/KCTD10/JKAMP/SPSB2/TRIM13/CDC27	59
BP	GO:0044344	cellular response to fibroblast growth factor stimulus	23/2159	143/18670	0.06351	0.4578	0.4241	EGR3/SPRY2/SPRED1/SPRY4/FGF1/FGF7/POLR2I/SPRED2/NPTN/FGFBP3/FGFR2/CEP57/SHISA2/FAT4/CD44/GTF2F2/KIF16B/DSTYK/FGFR1/POLR2G/SETX/FLRT1/CRKL	23
BP	GO:0032271	regulation of protein polymerization	33/2159	218/18670	0.06412	0.4616	0.4277	ABL1/VILL/ARHGAP28/ICAM1/ARF6/SLIT2/TMOD2/JMY/CDKN1B/RHOBTB1/ARPC5L/ARPC5/GMFB/FMN2/PFN4/EVL/ARPC2/MYO1C/FCHSD2/MAPRE1/CDK5R1/RICTOR/PFN2/ARPC4/VASP/TMOD3/TRIOBP/PREX1/WASL/RASA1/CDC42EP2/SPTA1/NIN	33
BP	GO:0015749	monosaccharide transmembrane transport	19/2159	114/18670	0.06438	0.4616	0.4277	GRB10/SLC2A10/APPL2/YES1/SESN2/SLC5A3/SLC2A11/C2CD5/SLC2A3/NR4A3/ENPP1/PRKCI/SLC50A1/SLC45A1/SLC23A2/RHOQ/HK2/TSC1/IGF1	19
BP	GO:0021545	cranial nerve development	10/2159	51/18670	0.06443	0.4616	0.4277	SIX1/ATP8B1/HES1/EGR2/HOXA1/NKX2-2/EPHB2/HOXA3/TIFAB/ADARB1	10
BP	GO:0048146	positive regulation of fibroblast proliferation	10/2159	51/18670	0.06443	0.4616	0.4277	JUN/CCNB1/CDK4/AQP1/EREG/SPHK1/PDGFRB/CDK6/LIG4/IGF1	10
BP	GO:0072523	purine-containing compound catabolic process	10/2159	51/18670	0.06443	0.4616	0.4277	HDDC3/NT5E/NUDT18/ACOT7/ADA/PDE4D/PNP/AMPD3/DNPH1/NUDT11	10
BP	GO:0030278	regulation of ossification	31/2159	203/18670	0.06458	0.4622	0.4282	BMP2/ATP2B1/OSR2/TWIST2/EGR2/JAG1/CLIC1/PRKD1/ACVR2A/ID2/PTK2/RBPJ/FGFR2/ENPP1/INTU/TP63/CEBPA/NOTCH1/ID3/DHRS3/OMD/PBX1/REST/CDK6/HOXA2/PRKACA/TMEM119/DDX5/KREMEN2/TOB2/IGF1	31
BP	GO:0048524	positive regulation of viral process	18/2159	107/18670	0.06542	0.4657	0.4315	DDX3X/KPNA2/JUN/VAPB/CHD1/SMC3/POLR2I/VPS4A/SRPK1/VAPA/GTF2F2/SP1/SNW1/POLR2G/NOTCH1/SMARCA4/CCNT1/ADARB1	18
BP	GO:0006298	mismatch repair	8/2159	38/18670	0.06554	0.4657	0.4315	ABL1/MCM9/MLH1/RPA2/MUTYH/PMS2P3/RPA1/PMS2P1	8
BP	GO:0006778	porphyrin-containing compound metabolic process	8/2159	38/18670	0.06554	0.4657	0.4315	COX15/SLC25A38/NFE2L1/ALAS1/ABCB6/CPOX/SLC11A2/SPTA1	8
BP	GO:0010939	regulation of necrotic cell death	8/2159	38/18670	0.06554	0.4657	0.4315	BIRC3/CFLAR/CAV1/PELI1/UCN/PPIF/BIRC2/SLC25A4	8
BP	GO:0032620	interleukin-17 production	8/2159	38/18670	0.06554	0.4657	0.4315	ARG2/SPHK1/TLR4/IL27RA/IFNG/IL36RN/MR1/IL12A	8
BP	GO:0060045	positive regulation of cardiac muscle cell proliferation	8/2159	38/18670	0.06554	0.4657	0.4315	CCNB1/HEY2/RBPJ/FGFR2/YAP1/FGFR1/NOTCH1/TBX2	8
BP	GO:0032868	response to insulin	40/2159	272/18670	0.06568	0.4662	0.4319	ATP2B1/SREBF1/EGR1/ATP6V1E2/CFLAR/ICAM1/EGR2/GRB10/CAT/CDK4/PDK2/APPL2/SESN2/RELA/PRKCZ/SESN3/SLC9A1/C2CD5/GKAP1/PCK2/SHC1/SOCS3/FOXC2/PKM/TNFSF10/MYO1C/ENPP1/ERRFI1/PRKCI/SP1/ATP6V1B2/RHOQ/CCND3/RAB8B/CPEB1/MYO5A/IGFBP1/PIK3CA/TSC1/CRY1	40
BP	GO:0035904	aorta development	11/2159	58/18670	0.06627	0.4693	0.4348	SIX1/LOXL1/HES1/JAG1/HEY2/RBPJ/SNX17/NOTCH1/PDGFRB/SEC24B/TBX2	11
BP	GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors	11/2159	58/18670	0.06627	0.4693	0.4348	CFLAR/ICAM1/TNFRSF10A/FEM1B/PMAIP1/TNFRSF10B/ITPRIP/TNFSF10/HMGB2/TNFAIP3/BCL2L1	11
BP	GO:0097696	STAT cascade	26/2159	166/18670	0.06655	0.4705	0.4359	GHR/LIF/HES1/ERCC6/CRLF3/CAV1/CLCF1/IFNAR2/IFNAR1/DOT1L/SOCS5/SOCS3/SH2B3/JAK2/IL22RA2/INPP5F/IFNG/NOTCH1/HSF1/STAMBP/IL12A/FYN/MGAT5/HDAC2/NMI/IGF1	26
BP	GO:1990778	protein localization to cell periphery	45/2159	311/18670	0.06673	0.4705	0.4359	MACF1/MMP14/ARF6/CAV1/EPHA2/PLEKHF1/RAB11FIP2/ARL13B/LIN7C/PRKCZ/C2CD5/VPS4A/RHOG/STAC/RAB11A/GPSM2/LIN7A/PRKCI/RAPGEF6/KIF5B/ARL6/BCL2L1/FAM126A/SYTL2/IFNG/NKD2/BBS2/PREPL/AP2M1/RHOQ/BLZF1/EPHB2/GOLPH3/RAB8B/MISP/PICALM/MYO5A/FLOT1/PIP5K1A/ZFYVE27/EXOC5/RILPL2/HRAS/EPB41L2/STXBP1	45
BP	GO:0048704	embryonic skeletal system morphogenesis	16/2159	93/18670	0.06708	0.4705	0.4359	SIX1/OSR2/MMP14/HOXA11/HOXA1/HOXA7/RDH10/HOXA5/HOXA6/SATB2/FGFR2/FOXC2/GSC/HOXA3/HOXA2/HOXD4	16
BP	GO:0043547	positive regulation of GTPase activity	57/2159	405/18670	0.06731	0.4705	0.4359	MAP4K4/ARHGAP19/RASA2/JUN/ARHGAP28/ICAM1/SMAP2/CCDC125/RGS4/SYDE2/CCL7/RP2/EPHA2/RAB11FIP2/F2RL1/DOCK10/DOCK7/TBC1D19/STARD8/BCAS3/RABGAP1/RGS17/ARHGDIA/DVL3/AGAP1/SIPA1L1/SIPA1L3/PLCB1/RHOG/DVL2/ARHGAP22/AGFG1/TIAM1/ACAP2/GDI1/ERRFI1/RAPGEF6/ECT2/ASAP1/SRGAP1/RGS2/SIPA1L2/PICALM/PREX1/VAV3/EVI5/ELMOD3/MYO9B/RGS16/PIP5K1A/CRKL/AGAP6/RASA1/CDC42EP2/HRAS/TSC1/SIPA1	57
BP	GO:0043900	regulation of multi-organism process	57/2159	405/18670	0.06731	0.4705	0.4359	BIRC3/AGO2/DDX3X/NLRX1/KPNA2/JUN/TRIM6/TNIP1/FOXP1/NFKBIL1/ERCC6/RIPK2/FBXL2/VAPB/CHD1/LRSAM1/CAV1/ARG2/TRIB1/SMURF2/TRIM59/F2RL1/SMC3/TRAF3IP2/POLR2I/ADA/VPS4A/SRPK1/PPM1B/PLCB1/VAPA/HMGA2/SETDB1/TRAF3/GTF2F2/AIM2/TNFAIP3/MID2/SP1/SNW1/POLR2G/IFNG/NOTCH1/SMARCA4/REST/HDAC2/CCDC87/FCN3/BIRC2/SIGLEC16/CCNT1/DDX5/STXBP1/TRIM13/NPR2/ADARB1/IGF1	57
BP	GO:0022604	regulation of cell morphogenesis	67/2159	484/18670	0.06731	0.4705	0.4359	ABL1/MACF1/EPHB3/ADNP/FMNL3/ICAM1/DIAPH1/ZSWIM6/SLIT2/CCL7/CXCL12/ZMYM5/WDR36/BCL9L/IFRD1/ARHGDIA/DVL3/MAP2K1/SIPA1L1/MKLN1/RHOG/RAB11A/PTK2/DVL2/SS18L1/LIMS2/TIAM1/LARP4/BDNF/ARPC2/SEMA7A/GDI1/CD44/ZMYM4/TNFRSF12A/CDK5R1/LINGO1/RYK/DLG4/CDC42SE1/PDPN/DNM3/RHOQ/EPHB2/TRIOBP/RHOC/ZMYM3/PREX1/GNA12/WDR1/CAPRIN1/ZRANB1/SEMA4G/FYN/CRKL/ZFYVE27/PDLIM5/EPHA4/MYCBP2/RASA1/CDC42EP2/SPTA1/NIN/ZNF135/ERMN/PLEKHO1/TTL	67
BP	GO:0048562	embryonic organ morphogenesis	42/2159	288/18670	0.06738	0.4705	0.4359	SIX1/SPRY2/OSR2/MMP14/HOXA11/IFT172/HES1/FZD2/HOXA1/EPHA2/HOXA7/RDH10/HOXA5/OTX1/ARL13B/HOXA6/HIPK1/ID2/SATB2/DVL2/FGFR2/PHACTR4/FOXC2/NR4A3/GSC/LRIG3/YAP1/TSHZ1/FGFR1/NOTCH1/IFT52/EPHB2/TRIOBP/ROR2/HOXA3/SEC24B/TIFAB/FOXF1/TBX2/GJB6/HOXA2/HOXD4	42
BP	GO:0071824	protein-DNA complex subunit organization	42/2159	288/18670	0.06738	0.4705	0.4359	HMGA1/ASF1A/SPTY2D1/NFE2/ATF7IP/ANP32E/BRF2/SMARCA1/CENPN/PSME4/POLR1E/DAXX/CENPO/PSMC2/HEY2/RPA2/VPS72/KAT6A/NAP1L3/RRN3/ACTR6/TAF6L/HMGB2/IPO4/RB1/TAF12/MCMDC2/MIS12/CENPU/THRA/SMARCA4/DMAP1/RPA1/GTF2H5/SMYD3/CHD1L/TSPYL4/HAT1/POLE3/BAZ2A/SWI5/TSPY26P	42
BP	GO:0006303	double-strand break repair via nonhomologous end joining	15/2159	86/18670	0.06763	0.4705	0.4359	ZBTB7A/PARP3/PAXIP1/POLL/DCLRE1A/RAD50/POLB/MLH1/HMGA2/TP53BP1/UBE2N/BABAM1/HSF1/LIG4/TFIP11	15
BP	GO:0006305	DNA alkylation	13/2159	72/18670	0.06786	0.4705	0.4359	FOS/ATF7IP/DNMT1/DNMT3A/HEMK1/KMT2E/BEND3/TDRD1/KDM1B/DMAP1/PIK3CA/MTA2/BAZ2A	13
BP	GO:0006306	DNA methylation	13/2159	72/18670	0.06786	0.4705	0.4359	FOS/ATF7IP/DNMT1/DNMT3A/HEMK1/KMT2E/BEND3/TDRD1/KDM1B/DMAP1/PIK3CA/MTA2/BAZ2A	13
BP	GO:0061180	mammary gland epithelium development	13/2159	72/18670	0.06786	0.4705	0.4359	CCND1/LBH/EPHA2/HOXA5/TNFSF11/ETV5/ID2/DEAF1/FGFR2/JAK2/FOXF1/VDR/PGR	13
BP	GO:0090114	COPII-coated vesicle budding	13/2159	72/18670	0.06786	0.4705	0.4359	VAPB/SEC23IP/PEF1/TRAPPC6A/KLHL12/VAPA/SEC24A/PPP6R1/CUL3/SEC31B/GOLGA2/TRAPPC2L/SEC24B	13
BP	GO:0001570	vasculogenesis	14/2159	79/18670	0.06791	0.4705	0.4359	SPRED1/CAV1/EPHA2/ACKR3/PAXIP1/HEY2/PTK2/YAP1/CCM2/NOTCH1/PDGFRB/JUNB/FOXF1/RASA1	14
BP	GO:1901293	nucleoside phosphate biosynthetic process	55/2159	390/18670	0.06913	0.4705	0.4359	ZBTB7A/NUPR1/GCDH/ACOT7/PDP2/HK1/ACACB/GSTZ1/PRKAG1/PDK2/PRPS1/PRPSAP2/CDADC1/IMPDH2/RAE1/PPCDC/RAD50/ELOVL7/FOXK2/HSD17B8/ADA/LCLAT1/PANK1/ELOVL6/PNP/AMPD3/PKM/ADPGK/PARP16/RFK/PRPS2/PFKP/NUP35/SLC26A1/IFNG/RNLS/SEH1L/DLAT/GPAM/UCK1/NUP98/HK2/NME5/NME3/NUP153/NME6/PFKM/ELOVL4/PDP1/ACSL4/NPR2/DCTD/NAMPT/IGF1/PPCS	55
BP	GO:0003214	cardiac left ventricle morphogenesis	4/2159	14/18670	0.06914	0.4705	0.4359	HEY2/RBPJ/NOTCH1/FOXF1	4
BP	GO:0006241	CTP biosynthetic process	4/2159	14/18670	0.06914	0.4705	0.4359	UCK1/NME5/NME3/NME6	4
BP	GO:0006268	DNA unwinding involved in DNA replication	4/2159	14/18670	0.06914	0.4705	0.4359	HMGA1/RECQL/RPA1/WRN	4
BP	GO:0015780	nucleotide-sugar transmembrane transport	4/2159	14/18670	0.06914	0.4705	0.4359	SLC35D1/SLC35B4/SLC35C1/SLC35A2	4
BP	GO:0031937	positive regulation of chromatin silencing	4/2159	14/18670	0.06914	0.4705	0.4359	ATF7IP/DNMT1/SETDB1/ZNF304	4
BP	GO:0044090	positive regulation of vacuole organization	4/2159	14/18670	0.06914	0.4705	0.4359	ULK1/LRSAM1/RALB/PIP4K2A	4
BP	GO:0044546	NLRP3 inflammasome complex assembly	4/2159	14/18670	0.06914	0.4705	0.4359	NLRC3/TLR4/CPTP/DHX33	4
BP	GO:0045064	T-helper 2 cell differentiation	4/2159	14/18670	0.06914	0.4705	0.4359	IL4R/PRKCZ/SOCS5/BCL6	4
BP	GO:0045346	regulation of MHC class II biosynthetic process	4/2159	14/18670	0.06914	0.4705	0.4359	JAK2/TLR4/IFNG/HDAC2	4
BP	GO:0045605	negative regulation of epidermal cell differentiation	4/2159	14/18670	0.06914	0.4705	0.4359	HES1/HOXA7/TP63/NOTCH1	4
BP	GO:0046036	CTP metabolic process	4/2159	14/18670	0.06914	0.4705	0.4359	UCK1/NME5/NME3/NME6	4
BP	GO:0046855	inositol phosphate dephosphorylation	4/2159	14/18670	0.06914	0.4705	0.4359	SYNJ2/IMPA1/INPP5B/MTMR7	4
BP	GO:0051547	regulation of keratinocyte migration	4/2159	14/18670	0.06914	0.4705	0.4359	MAP4K4/ARF6/FGF7/HBEGF	4
BP	GO:0070672	response to interleukin-15	4/2159	14/18670	0.06914	0.4705	0.4359	IL15RA/SHC1/PLCB1/ACSL4	4
BP	GO:0072216	positive regulation of metanephros development	4/2159	14/18670	0.06914	0.4705	0.4359	LIF/EGR1/PDGFRB/AGTR2	4
BP	GO:1901070	guanosine-containing compound biosynthetic process	4/2159	14/18670	0.06914	0.4705	0.4359	IMPDH2/NME5/NME3/NME6	4
BP	GO:1902570	protein localization to nucleolus	4/2159	14/18670	0.06914	0.4705	0.4359	NOL8/NVL/BYSL/WRN	4
BP	GO:1904748	regulation of apoptotic process involved in development	4/2159	14/18670	0.06914	0.4705	0.4359	TNFRSF1B/FOXC2/NOTCH1/VDR	4
BP	GO:0009261	ribonucleotide catabolic process	7/2159	32/18670	0.06917	0.4705	0.4359	HDDC3/NT5E/NUDT18/ACOT7/PDE4D/AMPD3/NUDT11	7
BP	GO:0015012	heparan sulfate proteoglycan biosynthetic process	7/2159	32/18670	0.06917	0.4705	0.4359	GLCE/TCF7L2/UGDH/HS2ST1/EXT1/EXTL2/HS3ST3A1	7
BP	GO:0046425	regulation of JAK-STAT cascade	22/2159	137/18670	0.06931	0.4709	0.4362	GHR/LIF/HES1/ERCC6/CRLF3/CAV1/CLCF1/DOT1L/SOCS3/SH2B3/CDK5R1/JAK2/IL22RA2/INPP5F/IFNG/NOTCH1/HSF1/IL12A/FYN/HDAC2/NLK/IGF1	22
BP	GO:0009062	fatty acid catabolic process	18/2159	108/18670	0.07039	0.4777	0.4426	ABHD2/GCDH/ETFB/ECI1/IVD/ACACB/ECH1/NUDT19/SESN2/PCCB/PCK2/EHHADH/MCEE/PECR/SLC25A17/ACAA1/ABHD3/ACOX3	18
BP	GO:0048661	positive regulation of smooth muscle cell proliferation	17/2159	101/18670	0.07154	0.4824	0.4469	JUN/FOXP1/ITGA2/DNMT1/ID2/HBEGF/EREG/MEF2D/MAP3K5/FGFR2/NR4A3/IRAK4/JAK2/PDGFRB/GNAI3/NAMPT/IGF1	17
BP	GO:0031529	ruffle organization	10/2159	52/18670	0.07187	0.4824	0.4469	ICAM1/ARF6/CAV1/SH3YL1/RHOG/SNX10/EVL/PFN2/PIP5K1A/HRAS	10
BP	GO:0032731	positive regulation of interleukin-1 beta production	10/2159	52/18670	0.07187	0.4824	0.4469	EGR1/RIPK2/HK1/PANX1/AIM2/JAK2/TLR4/IFNG/HSPB1/TRIM16	10
BP	GO:0006309	apoptotic DNA fragmentation	6/2159	26/18670	0.0719	0.4824	0.4469	DNASE2/HMGB2/KPNA1/HSF1/ST20/APAF1	6
BP	GO:0006346	methylation-dependent chromatin silencing	6/2159	26/18670	0.0719	0.4824	0.4469	ATF7IP/DNMT1/TET1/DNMT3A/SETDB1/ZNF304	6
BP	GO:0010460	positive regulation of heart rate	6/2159	26/18670	0.0719	0.4824	0.4469	RGS4/GCH1/HEY2/SLC1A1/ADA/PDE4D	6
BP	GO:0030206	chondroitin sulfate biosynthetic process	6/2159	26/18670	0.0719	0.4824	0.4469	CHST7/SLC35D1/UGDH/CSGALNACT2/CHST15/CHST12	6
BP	GO:0034204	lipid translocation	6/2159	26/18670	0.0719	0.4824	0.4469	ATP8B1/TMEM30B/ATP10D/ATP11B/ATP8B3/TMEM30A	6
BP	GO:0051788	response to misfolded protein	6/2159	26/18670	0.0719	0.4824	0.4469	RNF185/TOR1A/KLHL15/CUL3/ATXN3/DNAJB14	6
BP	GO:0060544	regulation of necroptotic process	6/2159	26/18670	0.0719	0.4824	0.4469	BIRC3/CFLAR/CAV1/PELI1/BIRC2/SLC25A4	6
BP	GO:0006865	amino acid transport	23/2159	145/18670	0.072	0.4824	0.4469	NFKBIE/SLC25A22/RGS4/SLC7A4/LRRC8A/SLC7A6/SLC25A38/NFE2L1/CTNS/ABAT/STX1A/SLC1A1/SFXN1/GIPC1/SLC1A4/RGS2/PDPN/GRM2/SLC38A2/SLC6A1/CLN3/SLC43A2/STXBP1	23
BP	GO:0010002	cardioblast differentiation	5/2159	20/18670	0.07268	0.4824	0.4469	RBPJ/EOMES/NOTCH1/REST/TBX2	5
BP	GO:0032495	response to muramyl dipeptide	5/2159	20/18670	0.07268	0.4824	0.4469	RIPK2/JAG1/RELA/TNFAIP3/NOTCH1	5
BP	GO:0043371	negative regulation of CD4-positive, alpha-beta T cell differentiation	5/2159	20/18670	0.07268	0.4824	0.4469	IL4R/CBFB/SOCS5/BCL6/SMAD7	5
BP	GO:0045655	regulation of monocyte differentiation	5/2159	20/18670	0.07268	0.4824	0.4469	ZBTB46/JUN/FOXP1/HOXA7/CDK6	5
BP	GO:0051580	regulation of neurotransmitter uptake	5/2159	20/18670	0.07268	0.4824	0.4469	ITGB3/RGS4/TOR1A/RGS2/FLOT1	5
BP	GO:0051767	nitric-oxide synthase biosynthetic process	5/2159	20/18670	0.07268	0.4824	0.4469	MAP2K6/JAK2/TLR4/IFNG/NAMPT	5
BP	GO:0051769	regulation of nitric-oxide synthase biosynthetic process	5/2159	20/18670	0.07268	0.4824	0.4469	MAP2K6/JAK2/TLR4/IFNG/NAMPT	5
BP	GO:0070262	peptidyl-serine dephosphorylation	5/2159	20/18670	0.07268	0.4824	0.4469	PPP2R2A/DUSP1/PPP2CB/PPTC7/PPM1F	5
BP	GO:0097734	extracellular exosome biogenesis	5/2159	20/18670	0.07268	0.4824	0.4469	VPS4A/RAB11A/SDC4/ATP13A2/IFNG	5
BP	GO:0032732	positive regulation of interleukin-1 production	11/2159	59/18670	0.07334	0.4859	0.4502	EGR1/RIPK2/HK1/PANX1/AIM2/JAK2/TLR4/IFNG/HSPB1/HDAC2/TRIM16	11
BP	GO:0001892	embryonic placenta development	15/2159	87/18670	0.07338	0.4859	0.4502	LIF/HES1/CDKN1C/EPAS1/NR2F2/MAP2K1/HEY2/SOCS3/RBPJ/FGFR2/EOMES/CEBPA/ZFAT/HSF1/JUNB	15
BP	GO:0060541	respiratory system development	30/2159	198/18670	0.07388	0.4887	0.4528	SIX1/SPRY2/SREBF1/LIF/MMP14/HES1/FGF1/RDH10/HOXA5/EPAS1/JMJD6/FGF7/MAP2K1/ADA/RBPJ/FGFR2/ERRFI1/FSTL3/YAP1/EIF4E/FGFR1/PDPN/CEBPA/NOTCH1/PDGFRB/THRA/MAN2A1/SEC24B/FOXF1/PGR	30
BP	GO:1904888	cranial skeletal system development	12/2159	66/18670	0.07406	0.4894	0.4534	SIX1/MMP14/HOXA1/RDH10/FGFR2/FOXC2/TP63/RAB23/TIFAB/SH3PXD2B/CRKL/HOXA2	12
BP	GO:0044843	cell cycle G1/S phase transition	43/2159	298/18670	0.07419	0.4897	0.4537	DDX3X/CCND1/DBF4/CCNB1/JADE1/PRIM1/SLFN11/CRLF3/CDK4/HINFP/RFWD3/BID/CDKN1B/ORC2/CDKN2D/ID2/ADAM17/KMT2E/APEX1/PLCB1/PCBP4/CNOT6L/RPA2/CDKN2C/KIF14/CNOT6/ORC4/TFDP2/CUL3/MUC1/GADD45A/EIF4E/RB1/GSPT1/CCND3/ZPR1/E2F4/RPA1/CDC25C/CDKN2B/CDK6/CDC7/POLE3	43
BP	GO:0034614	cellular response to reactive oxygen species	26/2159	168/18670	0.07464	0.4921	0.4559	FOS/ABL1/JUN/CFLAR/PDK2/AQP1/GCH1/RELA/PPIF/APEX1/CAMKK2/SPHK1/CHUK/MAP3K5/NR4A3/OSER1/MPV17/ECT2/TNFAIP3/PRDX5/IMPACT/HSF1/GLRX2/SETX/HDAC2/ZNF580	26
BP	GO:1902807	negative regulation of cell cycle G1/S phase transition	21/2159	131/18670	0.07568	0.4985	0.4618	CCND1/CCNB1/JADE1/SLFN11/CDK4/RFWD3/CDKN1B/CDKN2D/PCBP4/CNOT6L/RPA2/CDKN2C/CNOT6/TFDP2/MUC1/GADD45A/RB1/E2F4/CDC25C/CDKN2B/CDK6	21
BP	GO:1904892	regulation of STAT cascade	23/2159	146/18670	0.07652	0.5034	0.4664	GHR/LIF/HES1/ERCC6/CRLF3/CAV1/CLCF1/DOT1L/SOCS3/SH2B3/CDK5R1/JAK2/IL22RA2/INPP5F/IFNG/NOTCH1/HSF1/IL12A/FYN/MGAT5/HDAC2/NLK/IGF1	23
BP	GO:0042692	muscle cell differentiation	54/2159	385/18670	0.07682	0.5048	0.4677	SIX1/BMP2/ABL1/SGCD/IL4R/MMP14/CCNB1/EHD1/CFLAR/ASF1A/HES1/PARP2/RGS4/DNMT1/PTCD2/TMOD2/SYNE1/MYOM2/HOMER1/SLC9A1/IFRD1/HEY2/CHRNB1/FLNC/EREG/BOC/CHUK/RBPJ/CBY1/FGFR2/ACTC1/BDNF/PRKAR1A/RGS2/RB1/NOTCH1/PDGFRB/AGTR2/TMOD3/KLF5/WDR1/FLOT1/KCNH1/MYOZ2/SMYD3/SETD3/FOXF1/PDLIM5/ANKRD1/TBX2/TMEM119/PLEKHO1/TSC1/IGF1	54
BP	GO:0032872	regulation of stress-activated MAPK cascade	35/2159	237/18670	0.07694	0.5051	0.4679	BMP2/HIPK3/MAP4K4/DUSP1/GADD45G/ERCC6/RIPK2/IL1RN/CD27/DUSP3/F2RL1/TNFSF11/DAXX/PJA2/MAP3K3/DVL3/MAP2K1/PLCB1/MAP4K5/SPHK1/DVL2/ZNF622/MAP3K5/TIAM1/GADD45A/GADD45B/TLR4/MID1/IL36RN/ROR2/DTNBP1/DUSP19/EPHA4/HRAS/IL36B	35
BP	GO:0048284	organelle fusion	20/2159	124/18670	0.07751	0.5083	0.4709	TAP2/STX6/TMEM175/STX1A/C2CD5/VPS11/VPS4A/SPHK1/VPS8/MFN1/SNAPIN/KIF5B/OMA1/NKD2/USP30/RAB8B/VAV3/VAMP4/GNAI3/STXBP1	20
BP	GO:0031032	actomyosin structure organization	30/2159	199/18670	0.07778	0.5087	0.4713	ABL1/ARHGAP28/CFLAR/FHOD1/TMOD2/MYOM2/SLC9A1/VPS4A/CNN2/SDC4/FRMD7/ZYX/KCTD13/ACTC1/EVL/CUL3/PRKAR1A/ECT2/PFN2/PDGFRB/TMOD3/RHOC/WDR1/PPM1F/MYOZ2/SH3PXD2B/ANKRD1/EPB41L2/PHLDB2/TSC1	30
BP	GO:0006221	pyrimidine nucleotide biosynthetic process	9/2159	46/18670	0.07783	0.5087	0.4713	PRPS1/CDADC1/LCLAT1/GPAM/UCK1/NME5/NME3/NME6/DCTD	9
BP	GO:0032480	negative regulation of type I interferon production	9/2159	46/18670	0.07783	0.5087	0.4713	IKBKE/NLRX1/RELB/IRF3/PPM1B/NLRC3/RNF135/TNFAIP3/NMI	9
BP	GO:0051196	regulation of coenzyme metabolic process	16/2159	95/18670	0.07831	0.5113	0.4737	ZBTB7A/NUPR1/PDP2/GSTZ1/PRKAG1/PDK2/RAE1/NUP35/IFNG/SEH1L/COQ3/PPTC7/NUP98/NUP153/PDP1/IGF1	16
BP	GO:0043409	negative regulation of MAPK cascade	28/2159	184/18670	0.0785	0.512	0.4743	DUSP6/HIPK3/ABL1/SPRY2/DUSP1/SPRED1/DUSP5/LIF/TNIP1/SPRY4/CDK5RAP3/RGS4/CAV1/LAX1/DUSP3/F2RL1/CAMK2N1/SPRED2/DUSP7/SH2B3/RNF149/ERRFI1/RGS2/TLR4/EPHB2/DUSP19/CASC2/EMILIN1	28
BP	GO:0016072	rRNA metabolic process	37/2159	253/18670	0.07907	0.5148	0.4769	RSL1D1/DIMT1/NOL8/LYAR/POLR1E/RPS24/NVL/DIS3L/WDR36/UTP3/RRP15/DROSHA/SPIN1/ESF1/EXOSC8/RRNAD1/LSM6/ZNHIT6/FAM207A/DDX11/MPHOSPH6/RIOK1/PES1/BYSL/NOP10/UTP15/PIH1D2/PELO/RCL1/SMARCA4/NAF1/GTF2H5/EXOSC4/DDX21/GEMIN4/PA2G4/EXOSC10	37
BP	GO:0021700	developmental maturation	41/2159	284/18670	0.07915	0.5148	0.4769	BMP2/ABHD2/TMEM79/CBFB/ZBTB7A/CCNB1/DDIT3/SCARF1/HES1/CDKN1C/SYBU/RAB32/FEM1B/HOXA5/EPAS1/B4GALT5/SOX8/ID2/NSUN2/EREG/RBPJ/KIF14/SEMG2/FAT4/B4GALT6/SNAPIN/CDK5R1/FGFR1/POU2F2/DLG4/RB1/CEBPA/NR4A2/PICALM/MYO5A/NOM1/PGR/PRKACA/STXBP1/NPR2/IGF1	41
BP	GO:0045191	regulation of isotype switching	7/2159	33/18670	0.07942	0.5148	0.4769	CLCF1/PARP3/PAXIP1/BCL6/MLH1/TP53BP1/IL27RA	7
BP	GO:0048821	erythrocyte development	7/2159	33/18670	0.07942	0.5148	0.4769	ZBTB7A/LYAR/JMJD6/BCL6/SH2B3/TMOD3/SLC11A2	7
BP	GO:0061097	regulation of protein tyrosine kinase activity	15/2159	88/18670	0.07944	0.5148	0.4769	ERCC6/CAV1/VPS25/SOCS5/ADAM17/SHC1/EREG/DVL2/BDNF/ERRFI1/PAK2/DLG4/CD24/FYN/EPHA4	15
BP	GO:0070125	mitochondrial translational elongation	15/2159	88/18670	0.07944	0.5148	0.4769	MRPL40/MRPS6/OXA1L/MRPS18C/MRPL17/MRPS14/MRPS18A/MRPL11/MRPL10/MRPS16/MRPL24/MRPS33/MRPS31/MRPS36/MRPL2	15
BP	GO:0043331	response to dsRNA	10/2159	53/18670	0.07984	0.5166	0.4786	RIPK2/CAV1/IRF3/PELI1/NFKB1/PMAIP1/RALB/FLOT1/DDX21/RFTN2	10
BP	GO:0006310	DNA recombination	42/2159	292/18670	0.07989	0.5166	0.4786	KPNA2/RECQL/NABP1/CLCF1/PARP3/RFWD3/RAD54L/PAXIP1/POLL/BCL6/RAD50/POLB/MCM9/FAN1/APEX1/RAD51D/MLH1/RPA2/EXD2/FIGN/RAD54B/NSMCE1/TP53BP1/FEN1/NSMCE2/KLHL15/UBE2N/THAP9/HMGB2/RAD51C/IL27RA/MCMDC2/KPNA1/TERF2IP/SETX/RPA1/HELQ/RAD21/CDC7/LIG4/WRN/SWI5	42
BP	GO:0071496	cellular response to external stimulus	48/2159	339/18670	0.08026	0.5184	0.4803	FOSL1/FOS/ATP2B1/ULK1/SREBF1/NIM1K/JUN/ADNP/ITGA2/ICAM1/TNFRSF10A/PRKD1/PDK2/AQP1/NFKB1/SESN2/PMAIP1/MTMR3/NMRAL1/RALB/SESN3/SLC9A1/TNFRSF10B/CNN2/GABARAPL1/MAP3K5/TNRC6A/GADD45A/SNW1/TLR4/IMPACT/MYBBP1A/SEH1L/HSF1/GABARAP/NR4A2/GLRX2/SLC38A2/PIK3C2B/FYN/CDKN2B/ANKRD1/VDR/RRAGC/WRN/TSC1/NAMPT/SIPA1	48
BP	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	21/2159	132/18670	0.08064	0.5203	0.4821	DDX3X/TNFRSF10A/BID/PMAIP1/CASP4/TNFRSF10B/EGLN3/PDCD5/TNFSF15/MAP3K5/TNFSF10/CASP9/HSPE1/JAK2/KHDC1/HSF1/ST20/APAF1/PPM1F/REST/CASC2	21
BP	GO:0046794	transport of virus	11/2159	60/18670	0.08086	0.5206	0.4823	KPNA2/CAV1/RAE1/VPS37A/NUP35/XPO1/KPNA1/SEH1L/VPS28/NUP98/NUP153	11
BP	GO:0090342	regulation of cell aging	11/2159	60/18670	0.08086	0.5206	0.4823	ABL1/HMGA1/RSL1D1/ARG2/BCL6/MAP3K3/HMGA2/ZKSCAN3/YPEL3/CDK6/NAMPT	11
BP	GO:1900076	regulation of cellular response to insulin stimulus	13/2159	74/18670	0.08095	0.5207	0.4824	ATP2B1/GRB10/CDK4/APPL2/RELA/PRKCZ/SESN3/GKAP1/SOCS3/MYO1C/ENPP1/CCND3/TSC1	13
BP	GO:0006664	glycolipid metabolic process	18/2159	110/18670	0.08108	0.5209	0.4826	ST3GAL2/B4GALT3/MPPE1/ALDH5A1/PIGC/PGAP2/GLTP/B4GALT5/NEU1/B4GALT6/CPTP/PIGB/GBGT1/PIGV/PGAP3/SUMF2/CLN3/CREM	18
BP	GO:1903829	positive regulation of cellular protein localization	46/2159	324/18670	0.08239	0.5288	0.4899	LIF/TMEM30B/CDK5RAP3/ARF6/RBM22/EPHA2/RAB11FIP2/BID/TCF7L2/SESN2/PMAIP1/BCAS3/C2CD5/VPS11/RHOG/NPTN/STAC/RAB11A/GPSM2/PDCD5/GPD1L/HPS4/TFDP2/MYO1C/PRKCI/CDK5R1/KIF5B/ECT2/TMEM30A/TP63/IFNG/NKD2/SAE1/MAP1A/EPHB2/ZPR1/VPS28/BICD1/DMAP1/FYN/PPP3CC/GAS8/MIEF2/PRKACA/HRAS/EPB41L2	46
BP	GO:0031929	TOR signaling	20/2159	125/18670	0.08271	0.5294	0.4905	NIM1K/EPM2A/SESN2/MAPKAPK5/FNIP2/RHEBL1/SESN3/LAMTOR3/LAMTOR4/MLST8/RICTOR/UBR1/SEH1L/GOLPH3/GNA12/SIK3/DEPTOR/RRAGC/PIK3CA/TSC1	20
BP	GO:1903708	positive regulation of hemopoiesis	28/2159	185/18670	0.08273	0.5294	0.4905	FOS/EGR3/IL4R/ZBTB46/CBFB/ZBTB1/LIF/JUN/MMP14/RIPK2/JAG1/TRIB1/CD27/HOXA5/TNFSF11/PRKCZ/SOCS5/BCL6/ACVR2A/ID2/ADA/PNP/HMGB2/RB1/IFNG/ROR2/IL12A/PCID2	28
BP	GO:0045785	positive regulation of cell adhesion	56/2159	403/18670	0.08308	0.5294	0.4905	EGR3/ABL1/MAP4K4/IL4R/CBFB/ZBTB1/CD274/LDB1/HSPH1/ITGA2/HES1/ICAM1/ECM2/RIPK2/CAV1/CXCL12/CD27/YES1/TNFSF11/RELA/PRKCZ/SOCS5/BCL6/ADA/SDC4/PNP/FOXC2/LIMS2/NR4A3/ARPC2/CD44/FSTL3/PAK2/JAK2/IFT74/PDCD1LG2/IFNG/PDPN/SMAD7/CD24/TRIOBP/PREX1/VAV3/ABI3BP/FLOT1/PPM1F/IL12A/FYN/CRKL/FOXF1/CDK6/SPTA1/PIK3CA/TSC1/EMILIN1/IGF1	56
BP	GO:1903320	regulation of protein modification by small protein conjugation or removal	34/2159	231/18670	0.08323	0.5294	0.4905	BIRC3/ABL1/TANK/NDFIP2/EGR1/TNIP1/RASSF5/RNF20/CDK5RAP3/RIPK2/CAV1/OTUD4/PAXIP1/DCUN1D2/PELI1/FEM1B/PEF1/DAXX/RELA/SPOPL/RNF111/SPHK1/UBE2N/CUL3/UBE2S/GOLGA2/TNFAIP3/SMAD7/VPS28/FYN/BIRC2/MYCBP2/CRY1/NMI	34
BP	GO:0009260	ribonucleotide biosynthetic process	42/2159	293/18670	0.08326	0.5294	0.4905	ZBTB7A/NUPR1/GCDH/ACOT7/PDP2/HK1/ACACB/GSTZ1/PRKAG1/PDK2/IMPDH2/RAE1/PPCDC/ELOVL7/FOXK2/HSD17B8/PANK1/ELOVL6/AMPD3/PKM/ADPGK/RFK/PFKP/NUP35/SLC26A1/IFNG/SEH1L/DLAT/UCK1/NUP98/HK2/NME5/NME3/NUP153/NME6/PFKM/ELOVL4/PDP1/ACSL4/NPR2/IGF1/PPCS	42
BP	GO:0051146	striated muscle cell differentiation	42/2159	293/18670	0.08326	0.5294	0.4905	SIX1/BMP2/SGCD/IL4R/MMP14/CCNB1/EHD1/CFLAR/PARP2/RGS4/PTCD2/TMOD2/MYOM2/HOMER1/SLC9A1/HEY2/CHRNB1/FLNC/CHUK/RBPJ/CBY1/ACTC1/BDNF/PRKAR1A/RGS2/RB1/NOTCH1/PDGFRB/AGTR2/TMOD3/KLF5/WDR1/FLOT1/KCNH1/MYOZ2/SMYD3/PDLIM5/ANKRD1/TMEM119/PLEKHO1/TSC1/IGF1	42
BP	GO:0034504	protein localization to nucleus	38/2159	262/18670	0.08361	0.5294	0.4905	SIX1/KPNA2/LIF/ZBTB7A/RASSF5/CDK5RAP3/NOL8/RBM22/KPNA4/TOR1A/SYNE1/APPL2/NVL/SESN2/SNUPN/HEATR3/TXNIP/TNPO3/ECT2/IPO4/BYSL/NUP35/IFNG/RAB23/XPO1/AGTR2/KPNA1/ZPR1/DMAP1/NUP98/FYN/NUP153/FAM53C/NXT1/SUPT7L/RANBP6/PYGO1/WRN	38
BP	GO:0010977	negative regulation of neuron projection development	24/2159	155/18670	0.08367	0.5294	0.4905	MAP4K4/ARF6/SLIT2/DENND5A/DPYSL3/IFRD1/ARHGDIA/PTK2/SEMA7A/GDI1/SNAPIN/CDK5R1/LINGO1/RYK/ASAP1/SRGAP2C/INPP5F/DNM3/NR2F1/EPHB2/SEMA4G/HDAC2/EPHA4/TSC1	24
BP	GO:0000460	maturation of 5.8S rRNA	6/2159	27/18670	0.0838	0.5294	0.4905	EXOSC8/MPHOSPH6/PES1/RCL1/EXOSC4/EXOSC10	6
BP	GO:0007176	regulation of epidermal growth factor-activated receptor activity	6/2159	27/18670	0.0838	0.5294	0.4905	VPS25/SOCS5/ADAM17/SHC1/EREG/ERRFI1	6
BP	GO:0061437	renal system vasculature development	6/2159	27/18670	0.0838	0.5294	0.4905	EGR1/CFLAR/HES1/FOXC2/NOTCH1/PDGFRB	6
BP	GO:0061440	kidney vasculature development	6/2159	27/18670	0.0838	0.5294	0.4905	EGR1/CFLAR/HES1/FOXC2/NOTCH1/PDGFRB	6
BP	GO:0071514	genetic imprinting	6/2159	27/18670	0.0838	0.5294	0.4905	CDKN1C/PCGF3/DNMT3A/KDM1B/DIRAS3/PIK3CA	6
BP	GO:0072207	metanephric epithelium development	6/2159	27/18670	0.0838	0.5294	0.4905	LIF/HES1/WWTR1/SOX8/FAT4/YAP1	6
BP	GO:2000144	positive regulation of DNA-templated transcription, initiation	6/2159	27/18670	0.0838	0.5294	0.4905	FOSL1/JUN/SUB1/PAXIP1/PSMC2/SETX	6
BP	GO:0045823	positive regulation of heart contraction	8/2159	40/18670	0.0841	0.5296	0.4907	RGS4/GCH1/UCN/HEY2/SLC1A1/ADA/PDE4D/RGS2	8
BP	GO:0072583	clathrin-dependent endocytosis	8/2159	40/18670	0.0841	0.5296	0.4907	SCYL2/FCHSD2/AP2A2/INPP5F/AP2M1/PICALM/WASL/AAK1	8
BP	GO:2000008	regulation of protein localization to cell surface	8/2159	40/18670	0.0841	0.5296	0.4907	ARF6/TOR1A/RAB11FIP5/GPD1L/BDNF/ASTN2/MAP1A/PICALM	8
BP	GO:0070302	regulation of stress-activated protein kinase signaling cascade	35/2159	239/18670	0.08436	0.5304	0.4914	BMP2/HIPK3/MAP4K4/DUSP1/GADD45G/ERCC6/RIPK2/IL1RN/CD27/DUSP3/F2RL1/TNFSF11/DAXX/PJA2/MAP3K3/DVL3/MAP2K1/PLCB1/MAP4K5/SPHK1/DVL2/ZNF622/MAP3K5/TIAM1/GADD45A/GADD45B/TLR4/MID1/IL36RN/ROR2/DTNBP1/DUSP19/EPHA4/HRAS/IL36B	35
BP	GO:0007219	Notch signaling pathway	29/2159	193/18670	0.08443	0.5304	0.4914	BMP2/S1PR3/RBM15/ZBTB7A/MMP14/IFT172/HES1/JAG1/CDKN1B/MESP2/BCL6/ADAM17/HEY2/RBPJ/FOXC2/FAT4/PRKCI/NEURL1B/IFT74/SNW1/TP63/CEBPA/NOTCH1/SLC35C1/PBX1/TBX2/ARRDC1/CDK6/AAK1	29
BP	GO:0006066	alcohol metabolic process	51/2159	364/18670	0.0846	0.5304	0.4914	BMP2/MINPP1/GPD2/SREBF1/SCARF1/SYNJ2/FGF1/CAT/ACACB/RDH10/NFKB1/GCH1/NFE2L1/SLC5A3/MVK/PPIP5K1/SGPP1/PCK2/PLCB1/PNPLA4/ELOVL6/SPHK1/IMPA1/PCBD2/AKR1A1/ARV1/PPIP5K2/SNX17/FGFR1/IMPAD1/SPTLC2/SP1/IFNG/CEBPA/DHRS3/INPP5B/CLCN2/NUS1/GPAM/COQ3/PECR/REST/QDPR/MTMR7/VDR/FDFT1/POR/MVD/GALR2/NUDT11/IGF1	51
BP	GO:0006414	translational elongation	21/2159	133/18670	0.0858	0.5304	0.4914	MRPL40/DPH5/MRPS6/TRNAU1AP/OXA1L/LTN1/MRPS18C/MRPL17/MRPS14/MRPS18A/ABTB1/MRPL11/MRPL10/SECISBP2L/MRPS16/MRPL24/MRPS33/MRPS31/DPH6/MRPS36/MRPL2	21
BP	GO:0000098	sulfur amino acid catabolic process	4/2159	15/18670	0.08598	0.5304	0.4914	ADO/MPST/BLMH/PCYOX1L	4
BP	GO:0006098	pentose-phosphate shunt	4/2159	15/18670	0.08598	0.5304	0.4914	RBKS/RPIA/DERA/PGLS	4
BP	GO:0009209	pyrimidine ribonucleoside triphosphate biosynthetic process	4/2159	15/18670	0.08598	0.5304	0.4914	UCK1/NME5/NME3/NME6	4
BP	GO:0015936	coenzyme A metabolic process	4/2159	15/18670	0.08598	0.5304	0.4914	ACOT7/PPCDC/PANK1/PPCS	4
BP	GO:0019321	pentose metabolic process	4/2159	15/18670	0.08598	0.5304	0.4914	RBKS/FGGY/DCXR/RPIA	4
BP	GO:0032352	positive regulation of hormone metabolic process	4/2159	15/18670	0.08598	0.5304	0.4914	EGR1/RDH10/IFNG/POR	4
BP	GO:0034134	toll-like receptor 2 signaling pathway	4/2159	15/18670	0.08598	0.5304	0.4914	RIPK2/F2RL1/PJA2/TNFAIP3	4
BP	GO:0036445	neuronal stem cell division	4/2159	15/18670	0.08598	0.5304	0.4914	AKNA/DOCK7/FGFR2/FGFR1	4
BP	GO:0045342	MHC class II biosynthetic process	4/2159	15/18670	0.08598	0.5304	0.4914	JAK2/TLR4/IFNG/HDAC2	4
BP	GO:0046184	aldehyde biosynthetic process	4/2159	15/18670	0.08598	0.5304	0.4914	BMP2/PNPO/CLCN2/REST	4
BP	GO:0046838	phosphorylated carbohydrate dephosphorylation	4/2159	15/18670	0.08598	0.5304	0.4914	SYNJ2/IMPA1/INPP5B/MTMR7	4
BP	GO:0055057	neuroblast division	4/2159	15/18670	0.08598	0.5304	0.4914	AKNA/DOCK7/FGFR2/FGFR1	4
BP	GO:1903543	positive regulation of exosomal secretion	4/2159	15/18670	0.08598	0.5304	0.4914	VPS4A/SDC4/ATP13A2/IFNG	4
BP	GO:0009199	ribonucleoside triphosphate metabolic process	48/2159	341/18670	0.08659	0.5304	0.4914	ZBTB7A/NUPR1/CCNB1/HK1/NDUFV2/COX15/PRKAG1/BID/NDUFA6/IMPDH2/NDUFB5/RAE1/PPIF/CTNS/FOXK2/BEND3/AMPD3/COX1/MFN1/PKM/ENPP1/ADPGK/PFKP/NUP35/IFNG/RAB23/SLC25A25/SEH1L/ATP6V1B2/RHOQ/NDUFS3/UQCR10/UCK1/NUP98/HK2/NME5/NME3/NDUFV1/NUP153/NDUFS2/NME6/ISCU/PFKM/NDUFB10/NDUFA11/SURF1/GNAI3/IGF1	48
BP	GO:0006450	regulation of translational fidelity	5/2159	21/18670	0.0867	0.5304	0.4914	VARS2/YRDC/DTD1/LARS2/PRORSD1P	5
BP	GO:0010801	negative regulation of peptidyl-threonine phosphorylation	5/2159	21/18670	0.0867	0.5304	0.4914	SPRY2/SPRED1/PARD3/SPRED2/SMAD7	5
BP	GO:0032516	positive regulation of phosphoprotein phosphatase activity	5/2159	21/18670	0.0867	0.5304	0.4914	MAGI2/JAK2/SLC39A10/PDGFRB/AGTR2	5
BP	GO:0033962	cytoplasmic mRNA processing body assembly	5/2159	21/18670	0.0867	0.5304	0.4914	PAN2/PAN3/CNOT6L/CNOT6/LSM4	5
BP	GO:0036120	cellular response to platelet-derived growth factor stimulus	5/2159	21/18670	0.0867	0.5304	0.4914	YES1/ERRFI1/HAS1/PDGFRB/FYN	5
BP	GO:0043984	histone H4-K16 acetylation	5/2159	21/18670	0.0867	0.5304	0.4914	KANSL1L/PHF20/MSL1/KANSL1/MSL3	5
BP	GO:1903055	positive regulation of extracellular matrix organization	5/2159	21/18670	0.0867	0.5304	0.4914	CFLAR/RB1/PDPN/PHLDB2/EMILIN1	5
BP	GO:1904886	beta-catenin destruction complex disassembly	5/2159	21/18670	0.0867	0.5304	0.4914	FZD2/CAV1/DVL3/FZD1/DVL2	5
BP	GO:2000810	regulation of bicellular tight junction assembly	5/2159	21/18670	0.0867	0.5304	0.4914	CBFB/EPHA2/TJP1/MYO1C/PRKACA	5
BP	GO:0010799	regulation of peptidyl-threonine phosphorylation	9/2159	47/18670	0.08687	0.5304	0.4914	SPRY2/SPRED1/TRIM6/RIPK2/PARD3/SPRED2/SPHK1/IRGM/SMAD7	9
BP	GO:1900744	regulation of p38MAPK cascade	9/2159	47/18670	0.08687	0.5304	0.4914	BMP2/DUSP1/GADD45G/PJA2/MAP3K3/SPHK1/MAP3K5/GADD45A/GADD45B	9
BP	GO:1901659	glycosyl compound biosynthetic process	9/2159	47/18670	0.08687	0.5304	0.4914	MTAP/NT5E/IMPDH2/ADA/UCK1/LCMT2/NME5/NME3/NME6	9
BP	GO:0090305	nucleic acid phosphodiester bond hydrolysis	43/2159	302/18670	0.08736	0.5323	0.4931	AGO2/POLG/DCP1A/PAN2/PAN3/DIS3L/DCLRE1A/RAD50/TATDN2/FAN1/APEX1/POLR2I/DROSHA/ELAC1/EXOSC8/CNOT6L/RPA2/POLR3K/EXD2/PARN/CNOT6/DXO/DNASE2/FEN1/ENPP1/HMGB2/HARBI1/PCF11/KPNA1/HSF1/PELO/RCL1/ST20/APAF1/RAD9A/RPA1/DNASE1/GTF2H5/CHD1L/ASTE1/EXOSC4/WRN/EXOSC10	43
BP	GO:0006006	glucose metabolic process	31/2159	209/18670	0.08745	0.5323	0.4931	GPD2/ALDH5A1/HK1/ACACB/PDK2/NFE2L1/DCXR/SESN2/PMAIP1/PPP1R3E/FOXK2/PCK2/GALM/AKR1A1/PKM/COX11/ENPP1/ADPGK/SLC37A4/PFKP/SLC35B4/GDPGP1/OMA1/DLAT/HK2/PFKM/CREM/NISCH/PIK3CA/CRY1/IGF1	31
BP	GO:0071229	cellular response to acid chemical	31/2159	209/18670	0.08745	0.5323	0.4931	SIX1/PTGER2/SREBF1/EGR1/CCNB1/DNMT1/PTGFR/CDK4/DNMT3A/AQP1/YES1/SESN2/SESN3/LAMTOR3/FGFR2/BRINP1/LAMTOR4/YAP1/BCL2L1/UBR1/SNW1/ID3/HSF1/AKAP8/CPEB1/SETX/FYN/HDAC2/HOXA2/RRAGC/SIPA1	31
BP	GO:0003281	ventricular septum development	13/2159	75/18670	0.08806	0.5323	0.4931	RBM15/HES1/FZD2/SLIT2/LMO4/ID2/HEY2/FZD1/RBPJ/FGFR2/LUZP1/SMAD7/NOTCH1	13
BP	GO:0015914	phospholipid transport	13/2159	75/18670	0.08806	0.5323	0.4931	ATP8B1/TMEM30B/ATP10D/PITPNB/GLTP/PLEKHA3/MFSD2A/APOC3/ATP11B/ATP8B3/TMEM30A/CPTP/PITPNC1	13
BP	GO:0051303	establishment of chromosome localization	13/2159	75/18670	0.08806	0.5323	0.4931	CCNB1/CHMP7/GEM/VPS4A/MLH1/RAB11A/FMN2/KIF14/CUL3/SEH1L/MIS12/KIF2B/TTL	13
BP	GO:1902117	positive regulation of organelle assembly	13/2159	75/18670	0.08806	0.5323	0.4931	ULK1/PAN2/MNS1/LRSAM1/PAN3/RALB/SDC4/GPSM2/CNOT6L/CNOT6/ASAP1/CEP120/PIP4K2A	13
BP	GO:0045667	regulation of osteoblast differentiation	20/2159	126/18670	0.08813	0.5323	0.4931	BMP2/TWIST2/JAG1/CLIC1/PRKD1/ACVR2A/ID2/PTK2/FGFR2/TP63/CEBPA/NOTCH1/ID3/REST/CDK6/HOXA2/PRKACA/TMEM119/DDX5/IGF1	20
BP	GO:0061005	cell differentiation involved in kidney development	10/2159	54/18670	0.08832	0.5323	0.4931	LIF/HES1/JAG1/WWTR1/FOXC2/MAGI2/FAT4/YAP1/NOTCH1/CD24	10
BP	GO:0030856	regulation of epithelial cell differentiation	24/2159	156/18670	0.08854	0.5323	0.4931	MAFF/CCND1/S1PR3/CBFB/LIF/HES1/CAV1/JAG1/CDKN1C/WWTR1/HOXA7/CDKN1B/HEY2/SGPP1/FAT4/ERRFI1/YAP1/MAFG/TP63/IFNG/NOTCH1/CD24/VDR/TRIM16	24
BP	GO:0009411	response to UV	22/2159	141/18670	0.08863	0.5323	0.4931	CCND1/ZBTB1/ERCC6/CAT/UBE4B/AQP1/RELA/CDKN2D/PRIMPOL/FEN1/CASP9/CIRBP/CCAR2/MAP4K3/IMPACT/C9orf116/ST20/E2F4/SDE2/IL12A/WRN/USP28	22
BP	GO:0070585	protein localization to mitochondrion	22/2159	141/18670	0.08863	0.5323	0.4931	SREBF1/DDIT3/HK1/IMMP1L/BID/OXA1L/PMAIP1/DNAJC19/VPS11/PDCD5/HPS4/TOMM34/TFDP2/TP63/MTCH2/TIMM10/SAMM50/SAE1/GRPEL1/HK2/PPP3CC/DNLZ	22
BP	GO:0035924	cellular response to vascular endothelial growth factor stimulus	12/2159	68/18670	0.0887	0.5323	0.4931	EGR3/SPRY2/PRKD1/RELA/SPHK1/PGF/MYO1C/HSPB1/NOTCH1/PDGFRB/NUS1/VEGFC	12
BP	GO:0071887	leukocyte apoptotic process	17/2159	104/18670	0.08879	0.5323	0.4931	TSC22D3/CD274/FOXP1/ZC3H8/ARG2/IRF3/CXCL12/CD27/TRAF3IP2/BCL6/ADAM17/ADA/NR4A3/CASP9/SLC39A10/PIK3CD/CRKL	17
BP	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	17/2159	104/18670	0.08879	0.5323	0.4931	CFLAR/ICAM1/MCL1/TNFRSF10A/TCF7L2/RELA/TNFRSF10B/ITPRIP/TNFSF10/YAP1/HMGB2/TNFAIP3/BCL2L1/EYA4/FYN/PELI3/IGF1	17
BP	GO:0043624	cellular protein complex disassembly	32/2159	217/18670	0.0888	0.5323	0.4931	MRPL40/VILL/MAP1S/TMOD2/F2RL1/MRPS6/OXA1L/VPS4A/MRPS18C/C12orf65/MRPL17/MRPS14/MRPS18A/GSPT1/STMN3/MID1/MTRF1L/TMOD3/MAP1A/TRIOBP/MRPL11/MRPL10/WDR1/MRPS16/MRPL24/MRPS33/MRPS31/SPTA1/MRRF/KIF2B/MRPS36/MRPL2	32
BP	GO:0007040	lysosome organization	11/2159	61/18670	0.08884	0.5323	0.4931	HOOK2/TMEM175/HOOK3/AKTIP/HPS4/ZKSCAN3/SNAPIN/CCDC115/LAPTM4B/CLN3/ACP2	11
BP	GO:0048645	animal organ formation	11/2159	61/18670	0.08884	0.5323	0.4931	SIX1/HOXA11/HES1/FGF1/RDH10/MAP2K1/RBPJ/FGFR2/FGFR1/TP63/HOXA3	11
BP	GO:0080171	lytic vacuole organization	11/2159	61/18670	0.08884	0.5323	0.4931	HOOK2/TMEM175/HOOK3/AKTIP/HPS4/ZKSCAN3/SNAPIN/CCDC115/LAPTM4B/CLN3/ACP2	11
BP	GO:0048871	multicellular organismal homeostasis	66/2159	485/18670	0.08988	0.5358	0.4964	MAP2K6/PRKAB2/MKS1/TMEM79/IL4R/EGR1/LPCAT1/GADD45G/G0S2/LDB1/ITGB3/DDIT3/VPS54/ERCC6/NR1D2/GRB10/CAV1/ACACB/WWTR1/TLE3/RAB11FIP2/APPL2/AQP1/DOCK7/EPAS1/TNFSF11/POC1B/KRT16/HOMER1/MDM1/WDR36/ABAT/FTO/ADAM17/BBS10/RAB11A/ELOVL6/SPATA7/AMPD3/RBPJ/ACOT13/FOXC2/NR4A3/SNX10/PRKAR1A/YAP1/JAK2/TNFAIP3/UBASH3B/TP63/RB1/OMA1/TLR4/PRDM16/BBS2/HSPB1/NOTCH1/SLC22A5/HSF1/THRA/SLC11A2/PRKAR2A/PRKACA/TMEM119/PIK3CA/HOXC10	66
BP	GO:0009144	purine nucleoside triphosphate metabolic process	48/2159	342/18670	0.08988	0.5358	0.4964	ZBTB7A/NUPR1/CCNB1/HK1/NDUFV2/COX15/PRKAG1/BID/NDUFA6/IMPDH2/NDUFB5/RAE1/PPIF/CTNS/FOXK2/ADA/BEND3/AMPD3/COX1/MFN1/PKM/ENPP1/ADPGK/PFKP/NUP35/IFNG/RAB23/SLC25A25/SEH1L/ATP6V1B2/RHOQ/NDUFS3/UQCR10/NUP98/HK2/NME5/NME3/NDUFV1/NUP153/NDUFS2/NME6/ISCU/PFKM/NDUFB10/NDUFA11/SURF1/GNAI3/IGF1	48
BP	GO:0048736	appendage development	27/2159	179/18670	0.08991	0.5358	0.4964	MKS1/OSR2/HOXA11/IFT172/HOXA10/GDF5/B9D1/RDH10/NR2F2/FGFR2/INTU/FGFR1/IMPAD1/TP63/NOTCH1/IFT52/ECE1/ROR2/PBX1/GNA12/TMEM231/HDAC2/TBX2/ZNF141/KREMEN2/FRAS1/HOXC10	27
BP	GO:0060173	limb development	27/2159	179/18670	0.08991	0.5358	0.4964	MKS1/OSR2/HOXA11/IFT172/HOXA10/GDF5/B9D1/RDH10/NR2F2/FGFR2/INTU/FGFR1/IMPAD1/TP63/NOTCH1/IFT52/ECE1/ROR2/PBX1/GNA12/TMEM231/HDAC2/TBX2/ZNF141/KREMEN2/FRAS1/HOXC10	27
BP	GO:0048511	rhythmic process	42/2159	295/18670	0.09028	0.5358	0.4964	EGR3/MAP2K6/CIART/ARNTL2/RELB/SREBF1/JUN/EGR1/ADNP/NFKB2/EGR2/PER3/NR1D2/SLIT2/DBP/CDK4/TOP1/ENOX1/IMPDH2/HLF/ID2/ADA/EREG/HAS1/CDK5R1/CSNK1E/CCAR2/SP1/ATF5/ID3/MYBBP1A/SETX/SUV39H2/HDAC2/MAGED1/MYCBP2/PGR/NHLH2/CREM/DDX5/CRY1/NAMPT	42
BP	GO:0050768	negative regulation of neurogenesis	42/2159	295/18670	0.09028	0.5358	0.4964	MAP4K4/HES1/ARF6/SLIT2/JAG1/DENND5A/APPL2/HES4/SOX8/HOOK3/ID2/DPYSL3/IFRD1/ARHGDIA/NKX2-2/PTK2/BRINP1/SEMA7A/GDI1/PRTG/SNAPIN/CDK5R1/LINGO1/RYK/ASAP1/EIF4E/SRGAP2C/INPP5F/DNM3/NR2F1/NOTCH1/ID3/EPHB2/PBX1/REST/SEMA4G/HDAC2/DAAM2/EPHA4/ISL2/HOXA2/TSC1	42
BP	GO:1902806	regulation of cell cycle G1/S phase transition	30/2159	202/18670	0.09032	0.5358	0.4964	DDX3X/CCND1/CCNB1/JADE1/SLFN11/CDK4/RFWD3/BID/CDKN1B/CDKN2D/ID2/ADAM17/KMT2E/APEX1/PLCB1/PCBP4/CNOT6L/RPA2/CDKN2C/KIF14/CNOT6/TFDP2/MUC1/GADD45A/RB1/CCND3/E2F4/CDC25C/CDKN2B/CDK6	30
BP	GO:0000737	DNA catabolic process, endonucleolytic	7/2159	34/18670	0.09051	0.5358	0.4964	DNASE2/HMGB2/KPNA1/HSF1/ST20/APAF1/DNASE1	7
BP	GO:0009164	nucleoside catabolic process	7/2159	34/18670	0.09051	0.5358	0.4964	HDDC3/NT5E/NUDT18/CDADC1/ADA/PNP/DERA	7
BP	GO:0021522	spinal cord motor neuron differentiation	7/2159	34/18670	0.09051	0.5358	0.4964	ZC4H2/IFT172/LMO4/NFE2L1/NKX2-2/ISL2/HOXC10	7
BP	GO:0031128	developmental induction	7/2159	34/18670	0.09051	0.5358	0.4964	SIX1/BMP2/HOXA11/FGF1/HIPK1/SOX8/FGFR1	7
BP	GO:0032660	regulation of interleukin-17 production	7/2159	34/18670	0.09051	0.5358	0.4964	ARG2/SPHK1/TLR4/IL27RA/IFNG/IL36RN/IL12A	7
CC	GO:0005759	mitochondrial matrix	90/2257	469/19717	5.202e-07	0.0003683	0.0003444	POLG/MRPL40/CCNB1/DIMT1/TFAM/GCDH/ETFB/LIAS/PDP2/MCCC1/ECI1/COQ5/IVD/ARG2/ALDH5A1/BCKDHB/GSTZ1/ACSS3/MMAB/PDK2/ALDH7A1/TBRG4/DARS2/MRPS6/NUDT13/OXA1L/PCCB/FASTK/ALAS1/PPIF/DNAJC19/PRIMPOL/ABAT/BCAT2/HSD17B8/PCK2/HYKK/SHC1/HARS2/MPST/MPG/PABPC5/MRPS18C/C12orf65/MRPL17/DMGDH/ABHD10/ACP6/HMGCL/HSPE1/MRPS14/MCEE/DBT/ATXN3/CCAR2/IDH3A/BCL2L1/PRDX5/TRMT10C/ALDH6A1/MRPS18A/NR3C1/MARS2/MTRF1L/ATAD3A/NDUFS3/DLAT/GLRX2/COQ3/MRPL11/PPTC7/MRPL10/GRPEL1/STYXL1/MRPS16/RPUSD4/NDUFS2/MRPL24/MRPS33/ISCU/MRPS31/LARS2/POLDIP2/MRRF/PDP1/TRMT5/HOGA1/MRPS36/MRPL2/D2HGDH	90
CC	GO:0061695	transferase complex, transferring phosphorus-containing groups	56/2257	259/19717	1.81e-06	0.0006406	0.0005991	POLG/PRKAB2/CCND1/ULK1/NIM1K/ZBTB7A/CCNB1/TAF5L/PRIM1/CDK4/PRKAG1/PRPS1/PRPSAP2/POLR1E/CCNJ/SESN2/CDKN2D/SOCS5/ACVR2A/POLR2I/SOCS3/CHUK/POLR3K/MAP3K5/PKM/CDK12/PRKAR1A/GTF2F2/CDK5R1/PRPS2/TAF6L/SOCS7/PFKP/POLR1C/CKS2/SNW1/RB1/POLR2G/PHKB/TAF12/CKS1B/POLR3C/CCND3/PIK3CD/PIK3C2B/RPRD1A/GTF2H5/PFKM/PHKA1/PRKAR2A/CDK6/TAF5/TAF4B/CCNT1/POLE3/PIK3CA	56
CC	GO:1902911	protein kinase complex	28/2257	109/19717	2.768e-05	0.006533	0.006109	PRKAB2/CCND1/ULK1/NIM1K/ZBTB7A/CCNB1/CDK4/PRKAG1/CCNJ/SESN2/CDKN2D/ACVR2A/CHUK/MAP3K5/CDK12/PRKAR1A/CDK5R1/CKS2/SNW1/RB1/PHKB/CKS1B/CCND3/GTF2H5/PHKA1/PRKAR2A/CDK6/CCNT1	28
CC	GO:0035327	transcriptionally active chromatin	11/2257	25/19717	4.151e-05	0.007347	0.006871	ZC3H8/AFF4/BCAS3/PSIP1/KMT2E/ELL/TTC37/EXOSC4/PCID2/ICE2/EXOSC10	11
CC	GO:0005777	peroxisome	31/2257	134/19717	9.323e-05	0.008292	0.007754	IDH1/FAR2/PEX11A/CAT/LACC1/PEX11G/AKAP11/PEX11B/ECH1/NUDT19/PEX12/ISOC1/IMPDH2/MVK/EHHADH/HMGCL/MPV17/PRDX5/TTC1/PEX16/RAB8B/PECR/MYO5A/SLC25A17/PEX1/ACAA1/PXMP4/GRHPR/NUDT17/ACSL4/ACOX3	31
CC	GO:0042579	microbody	31/2257	134/19717	9.323e-05	0.008292	0.007754	IDH1/FAR2/PEX11A/CAT/LACC1/PEX11G/AKAP11/PEX11B/ECH1/NUDT19/PEX12/ISOC1/IMPDH2/MVK/EHHADH/HMGCL/MPV17/PRDX5/TTC1/PEX16/RAB8B/PECR/MYO5A/SLC25A17/PEX1/ACAA1/PXMP4/GRHPR/NUDT17/ACSL4/ACOX3	31
CC	GO:0005667	transcription factor complex	66/2257	365/19717	0.000109	0.008292	0.007754	FOS/SIX1/ARNTL2/HMGA1/CBFB/JUN/HOXA11/HOXA10/LDB1/TAF5L/DDIT3/SUB1/ATF7IP/NR1D2/RCOR3/BRF2/CDK4/LMO4/WWTR1/TLE3/TCF7L2/EPAS1/ASCC1/ATF6B/RELA/BCL9L/SOX8/DEAF1/APEX1/SATB2/RCOR2/RBPJ/AJUBA/NR4A3/GSC/TFDP2/GTF2F2/YAP1/TAF6L/RB1/POU2F1/ATF5/TAF12/E2F3/SMAD7/SIX6/CEBPA/THRA/NR4A2/KLF5/PBX1/JUNB/E2F4/ATF1/GTF2H5/FOXF1/VDR/MED7/TBX2/TAF5/TAF4B/NHLH2/CREM/TEAD1/MTA2/SMAD9	66
CC	GO:0005635	nuclear envelope	80/2257	464/19717	0.0001152	0.008292	0.007754	ABL1/SMOX/RBM15/SREBF1/ZBTB1/CREB3L4/MNS1/NPIPA1/CHMP7/PGRMC2/CDK4/LEMD3/KPNA4/TMEM97/TOR1A/HOXA7/MLX/SYNE1/CLIC1/AQP1/AKIRIN1/GCH1/TOR3A/CALR3/LMNB2/RAE1/PRKCZ/PHF20/SNUPN/IL15RA/STX1A/PDE4D/SPIN1/PLCB1/LMNB1/VAPA/ATP11B/INTS2/TMEM38A/AGFG1/C2orf42/CEP70/TMEM18/MYO1C/TMEM170A/THAP7/PARP16/AHCTF1/TMEM33/SH3BGRL2/CPNE1/BCL2L1/HTATIP2/NUP35/ZNF383/CPTP/XPO1/RNF13/DDX19B/DNAJB14/KPNA1/ROGDI/SEH1L/MTDH/TERF2IP/KCNH1/NUP98/ZNF224/CUEDC2/DNASE1/NUP153/SEPHS1/SLC22A18/KLHDC2/NXT1/PCID2/BICD2/TOR1B/GHDC/MGST2	80
CC	GO:0044438	microbody part	25/2257	100/19717	0.0001171	0.008292	0.007754	IDH1/FAR2/PEX11A/CAT/PEX11G/PEX11B/ECH1/NUDT19/PEX12/IMPDH2/EHHADH/HMGCL/MPV17/PRDX5/TTC1/PEX16/RAB8B/PECR/SLC25A17/PEX1/ACAA1/PXMP4/GRHPR/ACSL4/ACOX3	25
CC	GO:0044439	peroxisomal part	25/2257	100/19717	0.0001171	0.008292	0.007754	IDH1/FAR2/PEX11A/CAT/PEX11G/PEX11B/ECH1/NUDT19/PEX12/IMPDH2/EHHADH/HMGCL/MPV17/PRDX5/TTC1/PEX16/RAB8B/PECR/SLC25A17/PEX1/ACAA1/PXMP4/GRHPR/ACSL4/ACOX3	25
CC	GO:0000151	ubiquitin ligase complex	53/2257	282/19717	0.000186	0.01197	0.0112	ANAPC16/PHC2/MED30/FBXO25/RNF20/FBXO45/FBXL2/ARMC8/ZSWIM6/FBXO10/YPEL5/UBE4B/SMURF2/PCGF3/FBXO17/DCUN1D2/CDKN1B/PEF1/FBXO33/KLHL12/DCAF16/FBXO6/ENC1/SPOPL/DET1/MKLN1/KLHL3/KCTD13/KCTD5/KLHL2/KLHL15/UBE2N/CUL3/UBE2S/WDR26/CKS2/FBXL15/UBR1/ABTB1/DCAF17/FBXO24/CKS1B/FBXO32/DCAF7/FBXO21/ASB1/DDA1/KLHL42/MED20/MED7/KCTD10/SPSB2/CDC27	53
CC	GO:1902554	serine/threonine protein kinase complex	22/2257	88/19717	0.0002932	0.0173	0.01618	CCND1/ULK1/ZBTB7A/CCNB1/CDK4/CCNJ/SESN2/CDKN2D/ACVR2A/CHUK/CDK12/CDK5R1/CKS2/SNW1/RB1/PHKB/CKS1B/CCND3/GTF2H5/PHKA1/CDK6/CCNT1	22
CC	GO:0031965	nuclear membrane	54/2257	296/19717	0.0003515	0.01915	0.0179	ABL1/SMOX/RBM15/ZBTB1/CREB3L4/NPIPA1/CDK4/LEMD3/KPNA4/TMEM97/TOR1A/HOXA7/MLX/SYNE1/CLIC1/AQP1/AKIRIN1/GCH1/LMNB2/PHF20/IL15RA/STX1A/PDE4D/SPIN1/PLCB1/LMNB1/VAPA/ATP11B/INTS2/TMEM38A/C2orf42/CEP70/TMEM18/THAP7/AHCTF1/SH3BGRL2/CPNE1/BCL2L1/NUP35/ZNF383/CPTP/XPO1/RNF13/DDX19B/DNAJB14/MTDH/KCNH1/NUP98/ZNF224/CUEDC2/NUP153/SEPHS1/KLHDC2/TOR1B	54
CC	GO:0031461	cullin-RING ubiquitin ligase complex	33/2257	158/19717	0.000433	0.0219	0.02048	ANAPC16/FBXO25/FBXO45/FBXL2/ZSWIM6/FBXO17/CDKN1B/PEF1/FBXO33/KLHL12/DCAF16/FBXO6/ENC1/SPOPL/DET1/KLHL3/KCTD13/KCTD5/KLHL2/KLHL15/CUL3/UBE2S/CKS2/FBXL15/DCAF17/CKS1B/FBXO32/DCAF7/DDA1/KLHL42/KCTD10/SPSB2/CDC27	33
CC	GO:0000307	cyclin-dependent protein kinase holoenzyme complex	13/2257	42/19717	0.0005784	0.02516	0.02353	CCND1/CCNB1/CDK4/CCNJ/CDKN2D/CDK12/CKS2/SNW1/RB1/CKS1B/CCND3/CDK6/CCNT1	13
CC	GO:0031463	Cul3-RING ubiquitin ligase complex	12/2257	37/19717	0.000583	0.02516	0.02353	PEF1/KLHL12/ENC1/SPOPL/KLHL3/KCTD13/KCTD5/KLHL2/KLHL15/CUL3/KLHL42/KCTD10	12
CC	GO:0005874	microtubule	70/2257	416/19717	0.0006042	0.02516	0.02353	SPRY2/FAM161A/TTLL1/CLIP2/MAP1S/MACF1/RASSF5/HSPH1/CDK5RAP3/AKNA/HOOK2/CLMP/SYBU/BOD1L2/DCXR/DNAL1/ZNF804A/MDM1/HOOK3/POLB/BCAS3/KATNAL2/ODF2/RAB11A/TUBB4B/GABARAPL1/HAUS5/KIF14/FIGN/RASSF3/TTC30B/DNAL4/TIAM1/CEP57/CUL3/MAPRE1/HAUS6/KIF5B/GOLGA2/REEP3/MID2/ARL6/KIF16B/WDR47/SNPH/NICN1/DNM3/MID1/MAP1A/GABARAP/ROR2/MISP/EML4/DCDC2/EML6/BICD1/MYO5A/SHROOM2/TTC30A/TUBA4A/GAS8/STAU2/NIN/TUBA1B/KIF2B/TTLL6/TUBB3/TBCB/HAUS3/CDC27	70
CC	GO:0005779	integral component of peroxisomal membrane	7/2257	15/19717	0.0007122	0.02654	0.02482	FAR2/PEX11A/PEX11G/PEX11B/PEX12/PEX16/SLC25A17	7
CC	GO:0031231	intrinsic component of peroxisomal membrane	7/2257	15/19717	0.0007122	0.02654	0.02482	FAR2/PEX11A/PEX11G/PEX11B/PEX12/PEX16/SLC25A17	7
CC	GO:0005778	peroxisomal membrane	16/2257	60/19717	0.0008952	0.03018	0.02822	FAR2/PEX11A/CAT/PEX11G/PEX11B/PEX12/IMPDH2/MPV17/TTC1/PEX16/RAB8B/PECR/SLC25A17/PEX1/PXMP4/ACSL4	16
CC	GO:0031903	microbody membrane	16/2257	60/19717	0.0008952	0.03018	0.02822	FAR2/PEX11A/CAT/PEX11G/PEX11B/PEX12/IMPDH2/MPV17/TTC1/PEX16/RAB8B/PECR/SLC25A17/PEX1/PXMP4/ACSL4	16
CC	GO:0000123	histone acetyltransferase complex	20/2257	85/19717	0.001231	0.03962	0.03705	TAF5L/JADE1/KANSL1L/ZZZ3/MRGBP/PHF20/MSL1/ING4/JADE3/DPF2/KAT6A/TAF6L/KANSL1/TADA2A/TAF12/DMAP1/TAF5/SUPT7L/MSL3/POLE3	20
CC	GO:0001650	fibrillar center	27/2257	132/19717	0.001894	0.0583	0.05452	NFKBIE/MLLT1/KLF6/CHD1/AKNA/B3GNT9/TOP1/ZNF385B/AFF4/POLR1E/RAE1/DCLRE1A/DEAF1/ZNF415/KDM4A/NFIC/CDK12/UBE2N/DDX11/SMAD7/RAI14/CRIPT/UTP15/MTDH/JAZF1/ANKRD1/TAF4B	27
CC	GO:0031248	protein acetyltransferase complex	21/2257	95/19717	0.002171	0.06147	0.05749	TAF5L/JADE1/KANSL1L/ZZZ3/MRGBP/PHF20/MSL1/ING4/JADE3/NAA20/DPF2/KAT6A/TAF6L/KANSL1/TADA2A/TAF12/DMAP1/TAF5/SUPT7L/MSL3/POLE3	21
CC	GO:1902493	acetyltransferase complex	21/2257	95/19717	0.002171	0.06147	0.05749	TAF5L/JADE1/KANSL1L/ZZZ3/MRGBP/PHF20/MSL1/ING4/JADE3/NAA20/DPF2/KAT6A/TAF6L/KANSL1/TADA2A/TAF12/DMAP1/TAF5/SUPT7L/MSL3/POLE3	21
CC	GO:0000932	P-body	19/2257	84/19717	0.002617	0.06863	0.06419	AGO2/DCP1A/PAN2/BTBD1/MEX3B/TOP1/PAN3/SYNE1/PSMC2/LSM6/AJUBA/TNRC6A/EIF4E/POLR2G/LSM2/BTBD2/CPEB1/CAPRIN1/LSM4	19
CC	GO:0017053	transcriptional repressor complex	19/2257	84/19717	0.002617	0.06863	0.06419	CCND1/RELB/ZBTB7A/TBX18/JUN/RCOR3/HEY2/RCOR2/TBL1XR1/RBPJ/MTA3/SP1/PRDM16/REST/ZNF224/JAZF1/HDAC2/MTA2/BAZ2A	19
CC	GO:0031588	nucleotide-activated protein kinase complex	6/2257	14/19717	0.002967	0.07219	0.06751	PRKAB2/NIM1K/PRKAG1/SESN2/PRKAR1A/PRKAR2A	6
CC	GO:0005925	focal adhesion	65/2257	405/19717	0.003052	0.07219	0.06751	HMGA1/MAP4K4/PPFIBP1/MMP14/SPRY4/ITGB3/ITGA2/PALLD/NEXN/ICAM1/ARF6/FZD2/PEAK1/CAT/CAV1/EPHA2/ARL14EP/DOCK7/YES1/ARPC5L/STARD8/SLC9A1/ADAM17/PTPN12/MAP2K1/ARPC5/FLNC/FZD1/RHOG/PTK2/CNN2/SDC4/LAMTOR3/TGFB1I1/ARHGAP22/MPRIP/ZYX/AJUBA/LIMS2/PLAUR/ACTC1/TRIP6/EVL/ARPC2/CD44/PLEC/MAPRE1/JAK2/VASP/TM4SF20/HSPB1/PDGFRB/TRIOBP/ENAH/MISP/GNA12/FLOT1/NHS/AFAP1/FLRT1/PIP5K1A/HNRNPK/PRKAR2A/EPB41L2/PHLDB2	65
CC	GO:0090575	RNA polymerase II transcription factor complex	31/2257	163/19717	0.003059	0.07219	0.06751	FOS/HMGA1/CBFB/JUN/LDB1/TAF5L/DDIT3/NR1D2/TLE3/TCF7L2/ATF6B/BCL9L/TFDP2/GTF2F2/YAP1/TAF6L/RB1/POU2F1/TAF12/E2F3/CEBPA/THRA/PBX1/JUNB/E2F4/ATF1/GTF2H5/VDR/TAF5/TAF4B/TEAD1	31
CC	GO:0036464	cytoplasmic ribonucleoprotein granule	38/2257	212/19717	0.003349	0.07463	0.0698	AGO2/DDX3X/GHR/DCP1A/PAN2/BTBD1/BLNK/TAF5L/MEX3B/TOP1/PAN3/SYNE1/SHB/FXR2/ELAVL1/PSMC2/NSUN2/LSM6/AJUBA/PABPC5/POLI/TNRC6A/LARP4/GABPB1/CIRBP/UPF2/TDRD1/EIF4E/POLR2G/DDX19B/HENMT1/LSM2/BTBD2/CPEB1/CAPRIN1/HNRNPK/LSM4/LIG4	38
CC	GO:0005741	mitochondrial outer membrane	33/2257	178/19717	0.003496	0.07463	0.0698	DDX3X/NLRX1/ULK1/RNF185/MCL1/HK1/ACACB/AKAP1/RAB32/BCL2A1/RAB11FIP5/BID/MAOA/PMAIP1/CISD1/ABCB6/TOMM34/LETMD1/MFN1/BCL2L1/SAMM50/USP30/GPAM/HK2/SLC11A2/QTRT1/EPHA4/MIEF2/PGR/BRI3BP/ACSL4/ARMCX6/BCL2L2	33
CC	GO:0034399	nuclear periphery	26/2257	131/19717	0.003505	0.07463	0.0698	RUNX1T1/PAXIP1/DNMT3A/LMNB2/SMC3/PRKCZ/ENC1/SATB2/SRPK1/LMNB1/TGFB1I1/FIGN/GMCL1/AHCTF1/SCAF8/JAK2/ATXN3/STAG1/NUP35/SNW1/DCAF7/AKAP8/NUP98/NUP153/RAD21/HAT1	26
CC	GO:0005924	cell-substrate adherens junction	65/2257	408/19717	0.003638	0.07463	0.0698	HMGA1/MAP4K4/PPFIBP1/MMP14/SPRY4/ITGB3/ITGA2/PALLD/NEXN/ICAM1/ARF6/FZD2/PEAK1/CAT/CAV1/EPHA2/ARL14EP/DOCK7/YES1/ARPC5L/STARD8/SLC9A1/ADAM17/PTPN12/MAP2K1/ARPC5/FLNC/FZD1/RHOG/PTK2/CNN2/SDC4/LAMTOR3/TGFB1I1/ARHGAP22/MPRIP/ZYX/AJUBA/LIMS2/PLAUR/ACTC1/TRIP6/EVL/ARPC2/CD44/PLEC/MAPRE1/JAK2/VASP/TM4SF20/HSPB1/PDGFRB/TRIOBP/ENAH/MISP/GNA12/FLOT1/NHS/AFAP1/FLRT1/PIP5K1A/HNRNPK/PRKAR2A/EPB41L2/PHLDB2	65
CC	GO:0030992	intraciliary transport particle B	7/2257	19/19717	0.00369	0.07463	0.0698	IFT172/IFT88/TTC30B/IFT46/IFT74/IFT52/TTC30A	7
CC	GO:0030055	cell-substrate junction	65/2257	412/19717	0.004569	0.08834	0.08261	HMGA1/MAP4K4/PPFIBP1/MMP14/SPRY4/ITGB3/ITGA2/PALLD/NEXN/ICAM1/ARF6/FZD2/PEAK1/CAT/CAV1/EPHA2/ARL14EP/DOCK7/YES1/ARPC5L/STARD8/SLC9A1/ADAM17/PTPN12/MAP2K1/ARPC5/FLNC/FZD1/RHOG/PTK2/CNN2/SDC4/LAMTOR3/TGFB1I1/ARHGAP22/MPRIP/ZYX/AJUBA/LIMS2/PLAUR/ACTC1/TRIP6/EVL/ARPC2/CD44/PLEC/MAPRE1/JAK2/VASP/TM4SF20/HSPB1/PDGFRB/TRIOBP/ENAH/MISP/GNA12/FLOT1/NHS/AFAP1/FLRT1/PIP5K1A/HNRNPK/PRKAR2A/EPB41L2/PHLDB2	65
CC	GO:0035770	ribonucleoprotein granule	39/2257	223/19717	0.004617	0.08834	0.08261	AGO2/DDX3X/GHR/DCP1A/PAN2/BTBD1/BLNK/TAF5L/MEX3B/TOP1/PAN3/SYNE1/SHB/FXR2/ELAVL1/PSMC2/NSUN2/LSM6/AJUBA/PABPC5/POLI/TNRC6A/LARP4/GABPB1/CIRBP/UPF2/TDRD1/EIF4E/POLR2G/DDX19B/HENMT1/HSF1/LSM2/BTBD2/CPEB1/CAPRIN1/HNRNPK/LSM4/LIG4	39
CC	GO:0019867	outer membrane	36/2257	203/19717	0.00503	0.09372	0.08765	DDX3X/NLRX1/ULK1/SLC24A1/RNF185/MCL1/HK1/ACACB/AKAP1/RAB32/BCL2A1/SYNE1/RAB11FIP5/BID/MAOA/PMAIP1/CISD1/ABCB6/TOMM34/LETMD1/MFN1/BCL2L1/CPTP/SAMM50/USP30/GPAM/HK2/SLC11A2/QTRT1/EPHA4/MIEF2/PGR/BRI3BP/ACSL4/ARMCX6/BCL2L2	36
CC	GO:0016363	nuclear matrix	22/2257	109/19717	0.005596	0.1016	0.095	RUNX1T1/PAXIP1/DNMT3A/SMC3/PRKCZ/ENC1/SATB2/SRPK1/LMNB1/TGFB1I1/FIGN/GMCL1/AHCTF1/SCAF8/JAK2/ATXN3/STAG1/SNW1/DCAF7/AKAP8/RAD21/HAT1	22
CC	GO:0044452	nucleolar part	32/2257	178/19717	0.006397	0.1132	0.1059	NFKBIE/MLLT1/KLF6/CHD1/AKNA/B3GNT9/TOP1/ZNF385B/AFF4/POLR1E/RAE1/DCLRE1A/WDR36/DEAF1/ZNF415/KDM4A/NFIC/CDK12/UBE2N/DDX11/POLR1C/PES1/NOP10/SMAD7/SURF6/RAI14/CRIPT/UTP15/MTDH/JAZF1/ANKRD1/TAF4B	32
CC	GO:0016607	nuclear speck	62/2257	397/19717	0.006881	0.1188	0.1111	DDX3X/RBM15/DHX15/TAF5L/JADE1/EAF1/TAP2/HIF3A/ZNF217/PSME4/SMURF2/HEXIM2/ALKBH5/SETD1B/EPAS1/U2AF1L4/ASCC1/HIPK1/TATDN2/FTO/THOC6/RFXAP/KMT2E/APEX1/ATPAF2/PLCB1/VPS72/CBY1/SRSF8/KAT6A/POLI/WBP4/BDNF/CDK12/THAP7/NOC3L/RBM25/HAUS6/GADD45A/DDX39A/PNN/NR3C1/SNW1/ELL/SURF2/PRPF6/NR4A2/SRSF11/STK19/CDC25C/PIP5K1A/OSGEP/NXT1/PRPF4/PRKACA/RUFY1/SRSF10/ZC3H13/WRN/TFIP11/BAZ2A/NAMPT	62
CC	GO:0031968	organelle outer membrane	35/2257	201/19717	0.007496	0.1264	0.1182	DDX3X/NLRX1/ULK1/RNF185/MCL1/HK1/ACACB/AKAP1/RAB32/BCL2A1/SYNE1/RAB11FIP5/BID/MAOA/PMAIP1/CISD1/ABCB6/TOMM34/LETMD1/MFN1/BCL2L1/CPTP/SAMM50/USP30/GPAM/HK2/SLC11A2/QTRT1/EPHA4/MIEF2/PGR/BRI3BP/ACSL4/ARMCX6/BCL2L2	35
CC	GO:0005819	spindle	55/2257	347/19717	0.007792	0.1283	0.12	FAM161A/MAP1S/CCNB1/DIAPH1/YPEL5/BOD1L2/AGBL5/POC1B/SMC3/RAE1/MAP7D3/POLB/CEP85/GEM/KATNAL2/VPS4A/CBX1/NSUN2/SPIN1/ODF2/RAB11A/JTB/FMN2/GPSM2/TBL1XR1/HAUS5/KIF14/ACOT13/CUL3/MAPRE1/HAUS6/PPP2CB/DDX11/GOLGA2/ECT2/STAG1/NR3C1/RB1/MID1/HSPB1/HSF1/MISP/EML4/DCDC2/EVI5/RAD21/KLHL42/NIN/CDC7/TOPBP1/WDR73/KIF2B/CEP89/HAUS3/CDC27	55
CC	GO:0097431	mitotic spindle pole	8/2257	27/19717	0.008736	0.1406	0.1315	FAM161A/YPEL5/SMC3/RAE1/GPSM2/STAG1/HSF1/NIN	8
CC	GO:0000176	nuclear exosome (RNase complex)	6/2257	17/19717	0.00904	0.1422	0.133	NVL/DIS3L/EXOSC8/MPHOSPH6/EXOSC4/EXOSC10	6
CC	GO:0098798	mitochondrial protein complex	43/2257	262/19717	0.00959	0.1476	0.138	POLG/MRPL40/MCCC1/BCKDHB/IMMP1L/NDUFV2/PDK2/NDUFA6/MRPS6/NDUFB5/BCS1L/PPIF/DNAJC19/FOXRED1/COX1/MFN1/MCU/MRPS18C/C12orf65/MRPL17/MRPS14/DBT/TRMT10C/MRPS18A/TIMM10/SAMM50/NDUFS3/DLAT/UQCR10/MRPL11/MRPL10/GRPEL1/MRPS16/NDUFV1/NDUFS2/MRPL24/MRPS33/MRPS31/MICU1/NDUFB10/NDUFA11/MRPS36/MRPL2	43
CC	GO:0000314	organellar small ribosomal subunit	8/2257	28/19717	0.01103	0.1617	0.1512	MRPS6/MRPS18C/MRPS14/MRPS18A/MRPS16/MRPS33/MRPS31/MRPS36	8
CC	GO:0005763	mitochondrial small ribosomal subunit	8/2257	28/19717	0.01103	0.1617	0.1512	MRPS6/MRPS18C/MRPS14/MRPS18A/MRPS16/MRPS33/MRPS31/MRPS36	8
CC	GO:0072686	mitotic spindle	21/2257	109/19717	0.01139	0.1617	0.1512	FAM161A/DIAPH1/YPEL5/AGBL5/SMC3/RAE1/GEM/GPSM2/TBL1XR1/MAPRE1/GOLGA2/ECT2/STAG1/HSF1/MISP/EML4/DCDC2/NIN/CDC7/KIF2B/HAUS3	21
CC	GO:0036038	MKS complex	5/2257	13/19717	0.01142	0.1617	0.1512	MKS1/B9D1/TMEM17/TMEM231/CC2D2A	5
CC	GO:0036064	ciliary basal body	24/2257	133/19717	0.01584	0.2199	0.2057	MKS1/FAM161A/IFT172/JADE1/RP2/B9D1/ARMC9/POC1B/IFT88/SPATA7/CBY1/PIFO/TTC30B/AGBL2/IFT46/INTU/RPGR/BBS2/IFT52/TTC30A/GAS8/RILPL2/SDCCAG8/TTLL6	24
CC	GO:0070160	tight junction	23/2257	128/19717	0.01877	0.2533	0.2369	CCND1/AMOTL1/USP53/CDK4/EPHA2/CLMP/TJP1/LIN7C/PRKCZ/PARD3/MPP7/SIPA1L3/VAPA/MAGI2/LIN7A/PRKCI/ECT2/VASP/MTDH/FRMD4A/SHROOM2/NHS/MXRA8	23
CC	GO:0010008	endosome membrane	70/2257	479/19717	0.01896	0.2533	0.2369	SPPL2A/IKBKE/NDFIP2/CD274/EHD1/TMEM9/CYB561A3/ARF6/CHMP7/SCYL2/CAV1/STOML1/STEAP1/PLEKHF1/PDLIM4/TAB3/RAB11FIP2/RAB11FIP5/APPL2/TMEM175/VPS25/MMD/SLC1A1/VPS11/VPS4A/OSBPL9/ABCB6/RAB11A/SPHK1/LAMTOR3/ATP11B/STARD3NL/GNPNAT1/RAB22A/CMTM6/SNX10/ACAP2/LAMTOR4/IRAK4/SNX17/VPS37A/FURIN/AP2A2/SLC48A1/ATP13A2/KIF16B/INPP5F/TLR4/CPTP/IRAK2/RAB23/RNF13/AP2M1/INPP5B/ECE1/VPS28/YIPF2/RAB8B/KCNH1/DTNBP1/SLC9A7/LAPTM4B/PLEKHF2/SNX5/ZFYVE27/SLC11A2/EPHA4/RUFY1/KREMEN2/VPS45	70
CC	GO:0031252	cell leading edge	60/2257	403/19717	0.01997	0.2619	0.2449	ABL1/ATP2B1/SPRY2/AMOTL1/SLK/MACF1/SPRY4/LDB1/ITGB3/PALLD/DIAPH1/ARF6/SLC39A14/EPHA2/LMO4/PDLIM4/JMY/APPL2/PRKCZ/BCAS3/DPYSL3/SH3YL1/SLC9A1/ADAM17/C2CD5/ARPC5/MTMR9/MKLN1/PTK2/GABARAPL1/RAB22A/AJUBA/PHACTR4/TIAM1/ACTC1/KLHL2/EVL/ARPC2/MYO1C/CD44/PRKCI/TNFRSF12A/PDPN/VASP/ATP6V1B2/ENAH/MYO5A/FLOT1/NHS/PIP5K1A/SNX5/WASL/RASA1/CDK6/AAK1/PIK3CA/PLEKHO1/PHLDB2/TUBB3/TSC1	60
CC	GO:0044798	nuclear transcription factor complex	33/2257	201/19717	0.02104	0.2708	0.2533	FOS/HMGA1/CBFB/JUN/LDB1/TAF5L/DDIT3/NR1D2/BRF2/TLE3/TCF7L2/ATF6B/BCL9L/SOX8/TFDP2/GTF2F2/YAP1/TAF6L/RB1/POU2F1/TAF12/E2F3/CEBPA/THRA/PBX1/JUNB/E2F4/ATF1/GTF2H5/VDR/TAF5/TAF4B/TEAD1	33
CC	GO:0030127	COPII vesicle coat	5/2257	15/19717	0.02194	0.2774	0.2594	PEF1/KLHL12/SEC24A/SEC31B/SEC24B	5
CC	GO:0005881	cytoplasmic microtubule	14/2257	69/19717	0.02297	0.2853	0.2668	FAM161A/CLIP2/CLMP/DCXR/BCAS3/TTC30B/MAPRE1/ARL6/SNPH/MID1/MISP/BICD1/TTC30A/TUBA1B	14
CC	GO:0070603	SWI/SNF superfamily-type complex	15/2257	76/19717	0.02405	0.2936	0.2746	BAZ1A/ZBTB7A/ANP32E/SMARCA1/SS18L1/DPF2/ACTR6/ARID1B/MTA3/RB1/SMARCA4/DMAP1/HMGXB4/HDAC2/MTA2	15
CC	GO:0005782	peroxisomal matrix	11/2257	51/19717	0.02722	0.3196	0.2988	IDH1/FAR2/CAT/ECH1/NUDT19/EHHADH/HMGCL/PRDX5/ACAA1/GRHPR/ACOX3	11
CC	GO:0031907	microbody lumen	11/2257	51/19717	0.02722	0.3196	0.2988	IDH1/FAR2/CAT/ECH1/NUDT19/EHHADH/HMGCL/PRDX5/ACAA1/GRHPR/ACOX3	11
CC	GO:0030990	intraciliary transport particle	7/2257	27/19717	0.02879	0.3196	0.2988	IFT172/IFT88/TTC30B/IFT46/IFT74/IFT52/TTC30A	7
CC	GO:0005885	Arp2/3 protein complex	4/2257	11/19717	0.02915	0.3196	0.2988	ARPC5L/ARPC5/ARPC2/ARPC4	4
CC	GO:0031932	TORC2 complex	4/2257	11/19717	0.02915	0.3196	0.2988	SESN2/SESN3/MLST8/RICTOR	4
CC	GO:1990907	beta-catenin-TCF complex	4/2257	11/19717	0.02915	0.3196	0.2988	LDB1/TLE3/TCF7L2/BCL9L	4
CC	GO:0008023	transcription elongation factor complex	12/2257	58/19717	0.02934	0.3196	0.2988	ELP4/ERCC6/ZC3H8/EAF1/MLLT1/AFF4/CDK12/SNW1/RB1/ELL/CCNT1/ICE2	12
CC	GO:0016605	PML body	18/2257	99/19717	0.03121	0.3348	0.3131	HIPK3/IKBKE/CIART/MKNK2/NFE2/RFWD3/TCF7L2/DAXX/HIPK1/RNF111/RPA2/KAT6A/NSMCE2/RB1/HSF1/RPA1/TRIM16/TOPBP1	18
CC	GO:0090734	site of DNA damage	14/2257	73/19717	0.03576	0.3779	0.3534	ZBTB7A/SLFN11/PARP3/RFWD3/RAD50/OARD1/ARPC5/CBX1/RPA2/TP53BP1/ARPC2/PHF1/ARPC4/RPA1	14
CC	GO:0005743	mitochondrial inner membrane	67/2257	473/19717	0.03835	0.3866	0.3615	MRPL40/GPD2/SLC25A22/TMEM65/COQ5/IMMP1L/NDUFV2/COX15/TIMMDC1/SLC25A38/NOA1/NDUFA6/MRPS6/PTPMT1/OXA1L/NDUFB5/BCS1L/PPIF/DNAJC19/FOXRED1/MICU3/COX1/SFXN1/LETMD1/UQCC1/MCU/MRPS18C/COX11/MRPL17/ABCB10/MRPS14/COQ7/NDUFAF3/MPV17/NDUFAF4/BCL2L1/MRPS18A/OMA1/MTCH2/TMEM126B/TIMM10/SLC25A25/CPOX/ATAD3A/NDUFS3/TTC19/SLC25A53/UQCR10/COQ3/MRPL11/MRPL10/GRPEL1/MRPS16/NDUFV1/NDUFS2/MRPL24/SLC25A32/MRPS33/MRPS31/MICU1/SLC25A37/NDUFB10/NDUFA11/SURF1/MRPS36/MRPL2/SLC25A4	67
CC	GO:0005923	bicellular tight junction	21/2257	123/19717	0.03951	0.3866	0.3615	CCND1/AMOTL1/USP53/CDK4/CLMP/TJP1/LIN7C/PRKCZ/PARD3/MPP7/VAPA/MAGI2/LIN7A/PRKCI/ECT2/VASP/MTDH/FRMD4A/SHROOM2/NHS/MXRA8	21
CC	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex	4/2257	12/19717	0.03986	0.3866	0.3615	CDK12/SNW1/RB1/CCNT1	4
CC	GO:0030897	HOPS complex	4/2257	12/19717	0.03986	0.3866	0.3615	HOOK2/HOOK3/VPS11/AKTIP	4
CC	GO:0030914	STAGA complex	4/2257	12/19717	0.03986	0.3866	0.3615	TAF5L/TAF6L/TAF12/SUPT7L	4
CC	GO:0044615	nuclear pore nuclear basket	4/2257	12/19717	0.03986	0.3866	0.3615	NUP35/NUP98/NUP153/PCID2	4
CC	GO:0030687	preribosome, large subunit precursor	6/2257	23/19717	0.04063	0.3887	0.3635	ZNF593/NIP7/MAK16/RRP15/ZNF622/PES1	6
CC	GO:0005643	nuclear pore	16/2257	89/19717	0.04441	0.4193	0.3921	NPIPA1/RAE1/SNUPN/AGFG1/MYO1C/AHCTF1/TMEM33/NUP35/DDX19B/KPNA1/SEH1L/NUP98/NUP153/NXT1/PCID2/BICD2	16
CC	GO:0044455	mitochondrial membrane part	35/2257	229/19717	0.04595	0.428	0.4003	COQ5/IMMP1L/NDUFV2/COX15/NOA1/BID/NDUFA6/OXA1L/NDUFB5/BCS1L/PPIF/DNAJC19/FOXRED1/CISD1/ABCB6/COX1/SFXN1/MFN1/MCU/COX11/ABCB10/COQ7/TIMM10/SAMM50/NDUFS3/UQCR10/COQ3/GRPEL1/NDUFV1/NDUFS2/MICU1/NDUFB10/NDUFA11/SURF1/SLC25A4	35
CC	GO:0000421	autophagosome membrane	8/2257	36/19717	0.0473	0.4349	0.4067	ULK1/PRKD1/TEX264/GABARAPL1/TM9SF1/IRGM/GABARAP/TECPR1	8
CC	GO:0002102	podosome	7/2257	30/19717	0.04885	0.4401	0.4115	PALLD/TJP1/PTPN12/ASAP1/WDR1/SH3PXD2B/HNRNPK	7
CC	GO:0000178	exosome (RNase complex)	6/2257	24/19717	0.0491	0.4401	0.4115	NVL/DIS3L/EXOSC8/MPHOSPH6/EXOSC4/EXOSC10	6
CC	GO:1990204	oxidoreductase complex	19/2257	112/19717	0.05112	0.4524	0.4231	GPD2/BCKDHB/NDUFV2/PDK2/NDUFA6/NDUFB5/BCS1L/FOXRED1/GPD1L/COX1/DBT/NDUFS3/DLAT/UQCR10/NDUFV1/NDUFS2/NDUFB10/NDUFA11/MRPS36	19
CC	GO:0016281	eukaryotic translation initiation factor 4F complex	4/2257	13/19717	0.05249	0.4532	0.4239	EIF4B/EIF4G3/EIF4E/OTUD6B	4
CC	GO:0099243	extrinsic component of synaptic membrane	4/2257	13/19717	0.05249	0.4532	0.4239	KPNA2/TIAM1/PICALM/CRKL	4
CC	GO:0001726	ruffle	27/2257	172/19717	0.05528	0.4665	0.4363	SPRY2/MACF1/SPRY4/ITGB3/PALLD/DIAPH1/ARF6/EPHA2/APPL2/SH3YL1/ADAM17/C2CD5/MTMR9/MKLN1/RAB22A/TIAM1/KLHL2/MYO1C/TNFRSF12A/PDPN/ATP6V1B2/MYO5A/PIP5K1A/SNX5/RASA1/CDK6/PLEKHO1	27
CC	GO:0098687	chromosomal region	50/2257	349/19717	0.05592	0.4665	0.4363	CCNB1/ANAPC16/NABP1/DNMT1/CENPN/BOD1L2/DNMT3A/DOT1L/DAXX/CENPO/SMC3/ORC2/DCLRE1A/RAD50/THOC6/APEX1/RAD51D/CBX1/SCMH1/RPA2/SS18L1/ORC4/NSMCE1/TP53BP1/FEN1/NSMCE2/PPP2CB/AHCTF1/KANSL1/STAG1/TOX4/XPO1/POT1/SEH1L/MIS12/CENPU/HSF1/TERF2IP/NUP98/SETX/RPA1/SUV39H2/RAD21/RAD17/HAT1/ERCC6L/KIF2B/LIG4/WRN/TFIP11	50
CC	GO:0005774	vacuolar membrane	58/2257	412/19717	0.05601	0.4665	0.4363	SPPL2A/TMEM79/ULK1/LPCAT1/TMEM9/CYB561A3/TMEM192/PLEKHF1/PRKD1/TMEM175/TMEM138/THBD/CTNS/MMD/VPS11/VPS4A/ABCB6/VAPA/LAMTOR3/RAB37/TEX264/ATP11B/NEU1/STARD3NL/GABARAPL1/CMTM6/LAMTOR4/ENPP1/TM9SF1/SNAPIN/BRI3/AP2A2/CCDC115/SLC48A1/NAPG/ATP13A2/TMEM30A/CPNE1/IRGM/RNF13/DAGLB/SEH1L/ATP6V1B2/AP2M1/GABARAP/ECE1/TECPR1/FLOT1/ACPP/LAPTM4B/SLC11A2/AP5B1/CLN3/EVA1A/RRAGC/GNAI3/BLOC1S2/ACP2	58
CC	GO:0019005	SCF ubiquitin ligase complex	12/2257	64/19717	0.05734	0.4714	0.4408	FBXO25/FBXO45/FBXL2/FBXO17/FBXO33/FBXO6/CUL3/CKS2/FBXL15/CKS1B/FBXO32/SPSB2	12
CC	GO:0005769	early endosome	50/2257	350/19717	0.05825	0.4714	0.4408	CD274/EHD1/DIAPH2/WDFY2/ARF6/STX6/CAV1/PDLIM4/RAB32/ACKR3/RAB11FIP5/APPL2/F2RL1/VIPAS39/NIPA1/USP10/MAP2K1/SLC1A1/VPS11/VPS4A/APOC3/SPHK1/VPS8/ATP11B/RAB22A/CMTM6/SNX17/NEURL1B/ASTN2/KIF16B/INPP5F/TMEM230/TLR4/MGRN1/INPP5B/VPS28/STAMBP/PICALM/MYO5A/FLOT1/KCNH1/LAPTM4B/PLEKHF2/SNX5/SLC11A2/EPHA4/CLN3/RUFY1/NISCH/KREMEN2	50
CC	GO:1905354	exoribonuclease complex	6/2257	25/19717	0.05859	0.4714	0.4408	NVL/DIS3L/EXOSC8/MPHOSPH6/EXOSC4/EXOSC10	6
CC	GO:0030120	vesicle coat	11/2257	58/19717	0.06248	0.4971	0.4648	PEF1/KLHL12/COPZ2/COPG2/SEC24A/SEC31B/AP2A2/AP2M1/PICALM/SEC24B/SCYL1	11
CC	GO:1904949	ATPase complex	17/2257	101/19717	0.06637	0.5048	0.4721	BAZ1A/ZBTB7A/ANP32E/SMARCA1/SLC9A1/ABCB6/SS18L1/DPF2/ACTR6/ARID1B/MTA3/RB1/SMARCA4/DMAP1/HMGXB4/HDAC2/MTA2	17
CC	GO:0031314	extrinsic component of mitochondrial inner membrane	4/2257	14/19717	0.06705	0.5048	0.4721	COQ5/NOA1/COQ7/COQ3	4
CC	GO:0038201	TOR complex	4/2257	14/19717	0.06705	0.5048	0.4721	SESN2/SESN3/MLST8/RICTOR	4
CC	GO:0032587	ruffle membrane	16/2257	94/19717	0.06749	0.5048	0.4721	SPRY2/MACF1/SPRY4/ITGB3/DIAPH1/EPHA2/APPL2/SH3YL1/ADAM17/C2CD5/MTMR9/TIAM1/MYO1C/PDPN/PIP5K1A/PLEKHO1	16
CC	GO:0031985	Golgi cisterna	19/2257	116/19717	0.06845	0.5048	0.4721	ST3GAL2/B4GALT3/UXS1/ST3GAL1/FUT4/B4GALT5/GOLGA8N/SLC10A7/FUT11/RAB30/FUT8/B4GALT6/GOLGA2/CSGALNACT2/GOLPH3/YIPF2/MOB4/MAN2A1/B4GALNT3	19
CC	GO:0000313	organellar ribosome	15/2257	87/19717	0.06845	0.5048	0.4721	MRPL40/MRPS6/MRPS18C/C12orf65/MRPL17/MRPS14/MRPS18A/MRPL11/MRPL10/MRPS16/MRPL24/MRPS33/MRPS31/MRPS36/MRPL2	15
CC	GO:0005761	mitochondrial ribosome	15/2257	87/19717	0.06845	0.5048	0.4721	MRPL40/MRPS6/MRPS18C/C12orf65/MRPL17/MRPS14/MRPS18A/MRPL11/MRPL10/MRPS16/MRPL24/MRPS33/MRPS31/MRPS36/MRPL2	15
CC	GO:0000781	chromosome, telomeric region	25/2257	161/19717	0.07003	0.5068	0.4739	NABP1/DOT1L/ORC2/DCLRE1A/RAD50/THOC6/APEX1/RAD51D/CBX1/RPA2/ORC4/NSMCE1/TP53BP1/FEN1/NSMCE2/TOX4/POT1/TERF2IP/SETX/RPA1/RAD17/HAT1/LIG4/WRN/TFIP11	25
CC	GO:0031082	BLOC complex	5/2257	20/19717	0.07014	0.5068	0.4739	BCAS4/HPS4/SNAPIN/DTNBP1/BLOC1S2	5
CC	GO:0005746	mitochondrial respiratory chain	15/2257	88/19717	0.07418	0.5305	0.4961	NDUFV2/COX15/NDUFA6/OXA1L/NDUFB5/BCS1L/FOXRED1/COX1/NDUFS3/UQCR10/NDUFV1/NDUFS2/NDUFB10/NDUFA11/SURF1	15
MF	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	88/2189	439/17697	2.579e-06	0.002775	0.002664	MEOX1/FOSL1/FOS/SIX1/IER2/MAFF/SALL2/SREBF1/TBX18/JUN/EGR1/CSRNP2/CREB3L4/HOXA10/ZNF143/HOXD8/DDIT3/ZSCAN21/NFKB2/EGR2/SUB1/KLF6/ELK3/DBP/HOXA1/AKNA/IRF3/HOXA7/HOXA5/NFKB1/ETV4/NFE2L1/OTX1/EPAS1/CSRNP1/ATF6B/RELA/HLF/ETV5/SOX8/FOXK2/SATB2/MEF2D/RBPJ/NKRF/EOMES/FOXC2/HMGA2/ELK1/NR4A3/TFDP2/HSF2/NFIC/ETV1/STAG1/MAFG/POU2F2/SP1/NR3C1/TP63/ETV6/ATF5/E2F3/KLF13/SIX6/CEBPA/NOTCH1/ZFAT/NR4A2/KLF5/PBX1/JUNB/E2F4/CEBPZ/ATF1/REST/IRF2BPL/GMEB1/HNRNPK/FOXF1/TBX2/CARF/NR2C2/OVOL1/PGR/NHLH2/HOXD4/HOXC10	88
MF	GO:0019887	protein kinase regulator activity	44/2189	180/17697	5.769e-06	0.003103	0.002978	DDX3X/CCND1/ELP4/DBF4/SPRY2/SPRED1/CCNB1/ERCC6/CCNYL1/CDK4/CDKN1C/TRIB1/PRKAG1/HEXIM2/CCNJ/CDKN1B/DAXX/CDKN2D/GSKIP/MAP2K1/CAMK2N1/SPRED2/GMFB/SOCS3/ITPRIP/CDKN2C/PARP16/MLST8/PRKAR1A/CDK5R1/PAK2/CKS2/IRGM/CKS1B/HSPB1/CD24/CCND3/TRIB2/CDKN2B/DUSP19/PRKAR2A/CCNT1/PIK3CA/GPRC5C	44
MF	GO:0019207	kinase regulator activity	48/2189	207/17697	1.041e-05	0.003732	0.003582	DDX3X/CCND1/ELP4/DBF4/SPRY2/SPRED1/CCNB1/ERCC6/CCNYL1/CDK4/CDKN1C/TRIB1/PRKAG1/MOB1B/HEXIM2/CCNJ/CDKN1B/DAXX/CDKN2D/GSKIP/SOCS5/MAP2K1/CAMK2N1/SPRED2/GMFB/SOCS3/ITPRIP/LAMTOR3/CDKN2C/PARP16/MLST8/PRKAR1A/CDK5R1/SOCS7/PAK2/CKS2/IRGM/CKS1B/HSPB1/CD24/CCND3/TRIB2/CDKN2B/DUSP19/PRKAR2A/CCNT1/PIK3CA/GPRC5C	48
MF	GO:0004860	protein kinase inhibitor activity	20/2189	63/17697	4.351e-05	0.01171	0.01123	SPRY2/SPRED1/CDKN1C/TRIB1/HEXIM2/CDKN1B/CDKN2D/GSKIP/CAMK2N1/SPRED2/GMFB/SOCS3/ITPRIP/CDKN2C/PRKAR1A/HSPB1/TRIB2/CDKN2B/DUSP19/PRKAR2A	20
MF	GO:0003713	transcription coactivator activity	64/2189	319/17697	5.602e-05	0.01206	0.01157	ABL1/HMGA1/CBFB/JUN/NUPR1/MED30/TAF5L/JADE1/RNF20/NFKB2/SUB1/NFE2/NR1D2/HINFP/JMY/WWTR1/JMJD6/DAXX/GMEB2/BCL9L/ING4/RFXAP/APEX1/NKX2-2/TGFB1I1/SS18L1/KAT6A/HSF2/MED16/YAP1/TAF6L/HMGB2/ARID1B/CCAR2/MTA3/HTATIP2/SNW1/RB1/TADA2A/NR2F1/PRDM16/TAF12/CEBPA/USP21/PRPF6/THRA/MTDH/NFKBIB/SMARCA4/JUNB/NUP98/GMEB1/SETD3/MED20/ANKRD1/VDR/BIRC2/MED7/MAGED1/PPRC1/NR2C2/SUPT7L/MTA2/WBP2NL	64
MF	GO:0019210	kinase inhibitor activity	20/2189	67/17697	0.0001147	0.02056	0.01973	SPRY2/SPRED1/CDKN1C/TRIB1/HEXIM2/CDKN1B/CDKN2D/GSKIP/CAMK2N1/SPRED2/GMFB/SOCS3/ITPRIP/CDKN2C/PRKAR1A/HSPB1/TRIB2/CDKN2B/DUSP19/PRKAR2A	20
MF	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	16/2189	49/17697	0.0001713	0.02633	0.02527	CCND1/CCNB1/CCNYL1/CDK4/CDKN1C/HEXIM2/CCNJ/CDKN1B/CDKN2D/CDKN2C/CDK5R1/CKS2/CKS1B/CCND3/CDKN2B/CCNT1	16
MF	GO:0140097	catalytic activity, acting on DNA	45/2189	213/17697	0.0002034	0.02735	0.02625	DDX3X/POLG/HMGA1/RECQL/CHD2/DNMT1/CHD1/SMARCA1/TOP1/RAD54L/DNMT3A/ALKBH3/POLL/DCLRE1A/RAD50/POLB/PRIMPOL/TATDN2/FTO/CHD9/MCM9/FAN1/APEX1/MPG/EXD2/HMGA2/POLI/RAD54B/DNASE2/FEN1/THAP9/GTF2F2/DDX11/MUTYH/RAD51C/RAD54L2/RAD9A/SETX/DNASE1/HELQ/CHD1L/ERCC6L/POLE3/LIG4/WRN	45
MF	GO:0030291	protein serine/threonine kinase inhibitor activity	12/2189	32/17697	0.0002576	0.0308	0.02956	SPRY2/SPRED1/CDKN1C/HEXIM2/CDKN1B/CDKN2D/SPRED2/CDKN2C/PRKAR1A/HSPB1/CDKN2B/PRKAR2A	12
MF	GO:0030145	manganese ion binding	18/2189	62/17697	0.000363	0.03906	0.03749	ABL1/MPPE1/ARG2/PRIMPOL/PCK2/PPM1B/IMPA1/FEN1/HMGCL/POMGNT1/PPEF1/ATP13A2/EXTL2/CDIPT/MGAT5/PRKACA/MPPED2/WRN	18
MF	GO:0048487	beta-tubulin binding	12/2189	38/17697	0.001521	0.1367	0.1312	MAP1S/ADNP/VAPB/SMC3/BCAS3/PDCD5/GABARAPL1/PIFO/CDK5R1/IFT74/RGS2/GABARAP	12
MF	GO:0019209	kinase activator activity	21/2189	86/17697	0.001525	0.1367	0.1312	DDX3X/DBF4/SPRY2/CCNB1/ERCC6/MOB1B/DAXX/MAP2K1/LAMTOR3/PARP16/MLST8/CDK5R1/PAK2/CKS2/IRGM/CKS1B/CD24/DUSP19/CCNT1/PIK3CA/GPRC5C	21
MF	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	6/2189	12/17697	0.001689	0.1398	0.1342	CDKN1C/HEXIM2/CDKN1B/CDKN2D/CDKN2C/CDKN2B	6
MF	GO:0008138	protein tyrosine/serine/threonine phosphatase activity	13/2189	45/17697	0.002422	0.1745	0.1674	DUSP6/DUSP1/DUSP5/RNGTT/DUSP3/PTPMT1/DUSP7/DUSP28/SBF1/PPM1F/STYXL1/DUSP27/DUSP19	13
MF	GO:0001103	RNA polymerase II repressing transcription factor binding	11/2189	35/17697	0.00247	0.1745	0.1674	TCF7L2/BBS10/MIER2/RBPJ/GSC/MTA3/SP1/BBS2/DMAP1/HDAC2/MTA2	11
MF	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	7/2189	17/17697	0.002756	0.1745	0.1674	ZC3H4/ZC3H8/BCL6/EMX2/HSF2/HSF1/SMYD3	7
MF	GO:0044213	intronic transcription regulatory region DNA binding	7/2189	17/17697	0.002756	0.1745	0.1674	ZC3H4/ZC3H8/BCL6/EMX2/HSF2/HSF1/SMYD3	7
MF	GO:0030295	protein kinase activator activity	19/2189	80/17697	0.003493	0.2062	0.1979	DDX3X/DBF4/SPRY2/CCNB1/ERCC6/DAXX/MAP2K1/PARP16/MLST8/CDK5R1/PAK2/CKS2/IRGM/CKS1B/CD24/DUSP19/CCNT1/PIK3CA/GPRC5C	19
MF	GO:0019902	phosphatase binding	36/2189	185/17697	0.003709	0.2062	0.1979	IKBKE/PPP2R2A/SPRED1/SH2D4A/CSRNP2/FBXL2/PDLIM4/AKAP11/BOD1L2/CDKN1B/MTMR3/PARD3/PPP1R18/SH3YL1/SLC9A1/MTMR9/PTK2/SPHK1/RPA2/MAP3K5/PHACTR4/MAGI2/TRAF3/PPP6R1/PPME1/DLG4/SYTL2/ELL/TERF2IP/STYXL1/MYOZ2/STRN3/PPP1R32/CTTNBP2NL/CRY1/CDC27	36
MF	GO:0004527	exonuclease activity	19/2189	81/17697	0.004046	0.2062	0.1979	POLG/PAN2/PAN3/DIS3L/DCLRE1A/RAD50/FAN1/APEX1/CNOT6L/EXD2/PARN/CNOT6/DXO/FEN1/ENPP1/RAD9A/EXOSC4/WRN/EXOSC10	19
MF	GO:0051400	BH domain binding	5/2189	10/17697	0.004239	0.2062	0.1979	MCL1/BCL2A1/IRGM/BCL2L1/BCL2L2	5
MF	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding	6/2189	14/17697	0.004408	0.2062	0.1979	ZC3H4/ZC3H8/EMX2/HSF2/HSF1/SMYD3	6
MF	GO:0098847	sequence-specific single stranded DNA binding	6/2189	14/17697	0.004408	0.2062	0.1979	RAD50/RPA2/POT1/HSF1/TERF2IP/RPA1	6
MF	GO:0015631	tubulin binding	58/2189	336/17697	0.005206	0.2334	0.224	MAP4K4/FAM161A/JAKMIP3/CLIP2/MAP1S/MACF1/ADNP/HSPH1/VAPB/HOOK2/SYBU/RAB11FIP5/AGBL5/DNAL1/SMC3/RAE1/MDM1/MAP7D3/HOOK3/POLB/BCAS3/RABGAP1/KATNAL2/RAD51D/RAB11A/VAPA/STARD9/PDCD5/GABARAPL1/KIF14/PIFO/TIAM1/CEP70/CEP57/MAPRE1/CDK5R1/KIF5B/GOLGA2/IFT74/MID2/KIF16B/RGS2/DNM3/STMN3/ATF5/MID1/C9orf24/CRIPT/MAP1A/GABARAP/SPATA4/EML4/EML6/FYN/GAS8/KIF2B/BLOC1S2/TTLL6	58
MF	GO:0001047	core promoter binding	14/2189	55/17697	0.005954	0.2464	0.2365	FOS/AGO2/PRDM10/ZNF827/SOX8/RRN3/GADD45A/NR3C1/POU2F1/SMARCA4/REST/ZNF462/ZNF513/BAZ2A	14
MF	GO:0008408	3'-5' exonuclease activity	14/2189	55/17697	0.005954	0.2464	0.2365	POLG/PAN2/PAN3/DIS3L/RAD50/APEX1/CNOT6L/EXD2/PARN/CNOT6/RAD9A/EXOSC4/WRN/EXOSC10	14
MF	GO:0035035	histone acetyltransferase binding	9/2189	29/17697	0.006581	0.2531	0.2429	ZBTB7A/EGR1/KANSL1L/EPAS1/BCAS3/NR4A3/KANSL1/TRIM68/SP1	9
MF	GO:0072349	modified amino acid transmembrane transporter activity	6/2189	15/17697	0.006586	0.2531	0.2429	SLC19A2/CTNS/SLC1A4/SLC22A5/SLC25A32/SLC46A1	6
MF	GO:0033613	activating transcription factor binding	19/2189	85/17697	0.007026	0.255	0.2447	FOS/ZBTB7A/TBX18/JUN/LDB1/EGR2/RELA/HEY2/MEF2D/EOMES/TP53BP1/YAP1/RB1/PRDM16/SETD3/TBX2/NHLH2/HOXD4/DHX33	19
MF	GO:0001046	core promoter sequence-specific DNA binding	12/2189	45/17697	0.00711	0.255	0.2447	FOS/PRDM10/ZNF827/SOX8/RRN3/GADD45A/POU2F1/SMARCA4/REST/ZNF462/ZNF513/BAZ2A	12
MF	GO:0061608	nuclear import signal receptor activity	7/2189	20/17697	0.007864	0.273	0.262	KPNA2/KPNA4/SNUPN/TNPO3/IPO4/KPNA1/RANBP6	7
MF	GO:0001085	RNA polymerase II transcription factor binding	30/2189	155/17697	0.008193	0.2755	0.2644	FOS/TBX18/JUN/LDB1/EGR2/TCF7L2/ID2/HEY2/BBS10/MIER2/RBPJ/EOMES/ELK1/ZNHIT6/GSC/TP53BP1/MTA3/SP1/RB1/BBS2/ID3/MTDH/DMAP1/SETD3/HDAC2/ANKRD1/TBX2/NHLH2/TEAD1/MTA2	30
MF	GO:0016307	phosphatidylinositol phosphate kinase activity	6/2189	16/17697	0.00945	0.3081	0.2957	PIP5KL1/PIP4K2A/PIK3CD/PIK3C2B/PIP5K1A/PIK3CA	6
MF	GO:0042169	SH2 domain binding	10/2189	36/17697	0.01001	0.309	0.2965	ABL1/LAX1/PTK2/PAG1/JAK2/FGFR1/AFAP1/SH3PXD2B/RUFY1/NLK	10
MF	GO:0003779	actin binding	70/2189	431/17697	0.01005	0.309	0.2965	ABL1/VILL/CTNNAL1/MAP1S/MACF1/MSRB2/FBXO25/DIAPH2/FMNL3/PALLD/NEXN/MYO1H/DIAPH1/FHOD1/TMOD2/PDLIM4/JMY/SYNE1/PANX1/MYOM2/ARPC5L/PPP1R18/SMTN/ENC1/ARPC5/FLNC/GMFB/FMN2/PTK2/CNN2/KLHL3/MPRIP/INF2/AJUBA/PFN4/PHACTR4/KLHL2/EVL/ARPC2/GIPC1/MYO1C/PLEC/CDK5R1/PFN2/ARPC4/VASP/IMPACT/TMOD3/MAP1A/TRIOBP/MSRB1/ENAH/MISP/MYO5A/WDR1/SHROOM2/AFAP1/MYOZ2/DNASE1/CAP2/MYO9B/WASL/SETD3/PXK/PDLIM5/DAAM2/MYH2/SPTA1/EPB41L2/ERMN	70
MF	GO:0019200	carbohydrate kinase activity	7/2189	21/17697	0.01056	0.3132	0.3006	RBKS/HK1/FGGY/GNE/PFKP/HK2/PFKM	7
MF	GO:0043047	single-stranded telomeric DNA binding	5/2189	12/17697	0.01077	0.3132	0.3006	RAD50/RPA2/POT1/TERF2IP/RPA1	5
MF	GO:0003684	damaged DNA binding	15/2189	65/17697	0.01163	0.3294	0.3161	DCLRE1A/POLB/APEX1/RPA2/MPG/POLI/TP53BP1/FEN1/HMGB2/MUTYH/TP63/POT1/SDE2/RPA1/WRN	15
MF	GO:0000287	magnesium ion binding	38/2189	213/17697	0.01253	0.3348	0.3213	ABL1/ATP8B1/NIM1K/NUDT18/IDH1/ATP10D/RP2/PRPS1/PRPSAP2/ENOSF1/RPS6KA3/GEM/FAN1/MVK/FOXK2/SRPK1/PPM1B/SPHK1/IMPA1/ATP11B/MAP3K5/PKM/DXO/FEN1/HMGCL/IRAK4/PRPS2/ATP8B3/IDH3A/S100P/UBA2/SIK3/YDJC/CIB4/PRKACA/RRAGC/NLK/WRN	38
MF	GO:0004713	protein tyrosine kinase activity	26/2189	134/17697	0.01276	0.3348	0.3213	MAP2K6/HIPK3/ABL1/EPHB3/RIPK2/PEAK1/CLK4/EPHA2/YES1/HIPK1/TEC/TYK2/MAP2K1/NEK1/CAMKK2/PTK2/FGFR2/JAK2/DSTYK/FGFR1/PDGFRB/EPHB2/ROR2/FYN/SCYL1/EPHA4	26
MF	GO:0070851	growth factor receptor binding	26/2189	134/17697	0.01276	0.3348	0.3213	ITGB3/IL1RN/FGF1/YES1/SOCS5/FGF7/ADAM17/ESM1/SHC1/HBEGF/NPTN/EREG/IL11/PGF/TRIP6/IRAK4/LINGO1/JAK2/IL36RN/PDGFRB/VAV3/FLRT1/IL12A/FYN/IL36B/VEGFC	26
MF	GO:0004724	magnesium-dependent protein serine/threonine phosphatase activity	6/2189	17/17697	0.0131	0.3356	0.3221	PDP2/PPM1H/PPM1B/PPM1F/PDP1/PPM1G	6
MF	GO:0015605	organophosphate ester transmembrane transporter activity	8/2189	27/17697	0.01373	0.3436	0.3297	ATP8B1/TMEM30B/SLC37A4/TMEM30A/SLC25A25/SLC25A17/SLC25A32/SLC25A4	8
MF	GO:0004535	poly(A)-specific ribonuclease activity	5/2189	13/17697	0.01574	0.3765	0.3613	PAN2/PAN3/CNOT6L/PARN/CNOT6	5
MF	GO:0097617	annealing activity	5/2189	13/17697	0.01574	0.3765	0.3613	DDX3X/RECQL/SMARCA1/RAD54L/EIF4B	5
MF	GO:0003707	steroid hormone receptor activity	13/2189	56/17697	0.01724	0.3948	0.3789	ABHD2/PGRMC2/NR1D2/NR2F2/NR4A3/NR3C1/NR2F1/THRA/NR4A2/VDR/NR2C2/PGR/NR3C2	13
MF	GO:0051287	NAD binding	13/2189	56/17697	0.01724	0.3948	0.3789	UXS1/IDH1/PHGDH/HSD17B8/NUDT6/GPD1L/UGDH/IDH3A/RNLS/QDPR/NDUFV1/NDUFS2/GRHPR	13
MF	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	9/2189	34/17697	0.01954	0.4161	0.3993	FOS/PRDM10/ZNF827/SOX8/GADD45A/POU2F1/REST/ZNF462/ZNF513	9
MF	GO:0003725	double-stranded RNA binding	16/2189	75/17697	0.01959	0.4161	0.3993	AGO2/DDX3X/DHX15/ELAVL1/EIF4B/YRDC/DROSHA/TUBB4B/ILF2/MTDH/DDX21/STAU2/LRRFIP1/TUBA1B/DHX33/ADARB1	16
MF	GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	13/2189	57/17697	0.01988	0.4161	0.3993	PAN2/PAN3/DIS3L/DCLRE1A/APEX1/CNOT6L/EXD2/PARN/CNOT6/FEN1/RAD9A/EXOSC4/EXOSC10	13
MF	GO:0003697	single-stranded DNA binding	22/2189	113/17697	0.02	0.4161	0.3993	RBMS1/PRIM1/SUB1/NABP1/TOP1/RAD50/MCM9/RAD51D/MLH1/RPA2/DDX11/HMGB2/NUP35/POLR2G/SSBP2/POLR3C/MCMDC2/POT1/HSF1/TERF2IP/RPA1/HNRNPK	22
MF	GO:0043539	protein serine/threonine kinase activator activity	8/2189	29/17697	0.02123	0.4161	0.3993	DDX3X/DBF4/SPRY2/MAP2K1/PARP16/MLST8/CDK5R1/IRGM	8
MF	GO:0051059	NF-kappaB binding	8/2189	29/17697	0.02123	0.4161	0.3993	CDK5RAP3/RELA/APEX1/CPNE1/MTDH/AKAP8/HDAC2/TAF4B	8
MF	GO:0004842	ubiquitin-protein transferase activity	61/2189	382/17697	0.02136	0.4161	0.3993	RNF24/BIRC3/NEURL2/TRIM6/UBE2H/MED30/FBXO25/RNF20/PJA1/RNF185/ZFP91/FBXL2/LRSAM1/FBXO10/RFWD3/UBE4B/SMURF2/FBXO17/TRIM59/PELI1/FEM1B/PEX12/UBE2Q2/FBXO6/PJA2/ZNRF1/G2E3/RNF111/WDSUB1/RNF167/LTN1/KCTD13/NSMCE1/RNF135/TRAF3/RNF149/UBE2N/CUL3/UBE2S/NEURL1B/TRIM68/FBXL15/TNFAIP3/UBR1/FBXO24/RNF13/MGRN1/RNFT1/FBXO21/ASB1/FBXL22/IRF2BPL/PELI3/KLHL42/MED20/BIRC2/MED7/MYCBP2/HERC1/KCTD10/TRIM13	61
MF	GO:0005338	nucleotide-sugar transmembrane transporter activity	5/2189	14/17697	0.02204	0.4161	0.3993	SLC35D1/SLC35B4/SLC35C1/SLC35A2/SLC35E3	5
MF	GO:0035497	cAMP response element binding	5/2189	14/17697	0.02204	0.4161	0.3993	JUN/CREB3L4/ATF6B/HMGA2/NR4A3	5
MF	GO:0052745	inositol phosphate phosphatase activity	5/2189	14/17697	0.02204	0.4161	0.3993	MINPP1/IMPA1/IMPAD1/INPP5F/INPP5B	5
MF	GO:0008168	methyltransferase activity	37/2189	215/17697	0.02305	0.4277	0.4104	TPMT/TRMT6/PCMT1/COMTD1/DIMT1/PRDM10/DPH5/DNMT1/COQ5/DNMT3A/SETD1B/DOT1L/METTL7B/PRMT9/SETD4/PCMTD2/AS3MT/METTL17/HEMK1/BCDIN3D/NSUN2/RRNAD1/SETDB1/METTL18/ASH2L/TRMT10C/PRDM16/HENMT1/COQ3/LCMT2/FAM98B/SUV39H2/SMYD3/TRMT1L/SETD3/TRMT2A/TRMT5	37
MF	GO:0019787	ubiquitin-like protein transferase activity	64/2189	407/17697	0.02526	0.4595	0.4409	RNF24/BIRC3/NEURL2/TRIM6/UBE2H/MED30/FBXO25/RNF20/PJA1/EGR2/RNF185/ZFP91/FBXL2/LRSAM1/FBXO10/RFWD3/UBE4B/SMURF2/FBXO17/TRIM59/PELI1/FEM1B/PEX12/UBE2Q2/FBXO6/PJA2/ZNRF1/G2E3/RNF111/WDSUB1/RNF167/LTN1/KCTD13/NSMCE1/RNF135/TRAF3/NSMCE2/RNF149/UBE2N/CUL3/UBE2S/NEURL1B/TRIM68/FBXL15/TNFAIP3/UBR1/FBXO24/RNF13/MGRN1/RNFT1/FBXO21/ASB1/UFC1/FBXL22/IRF2BPL/PELI3/KLHL42/MED20/BIRC2/MED7/MYCBP2/HERC1/KCTD10/TRIM13	64
MF	GO:0140098	catalytic activity, acting on RNA	61/2189	386/17697	0.02591	0.4595	0.4409	AGO2/DDX3X/PUS10/TRMT6/PAN2/DHX15/DIMT1/PRIM1/VARS2/PTRH2/PAN3/ALKBH3/POLR1E/ALKBH5/DARS2/JMJD6/DIS3L/PRIMPOL/FTO/APEX1/POLR2I/BCDIN3D/DDX50/DROSHA/NSUN2/HARS2/ELAC1/RRNAD1/CNOT6L/POLR3K/PARN/CNOT6/RAD54B/FEN1/POLR1C/DDX39A/TRMT10C/MARS2/POLR2G/DDX19B/TYW1/POLR3C/HENMT1/DTD1/RCL1/LCMT2/AQR/TRMT1L/MED20/TRMT2A/EXOSC4/DDX21/QTRT1/LARS2/TRMT5/DDX5/PRORSD1P/DHX33/PTRHD1/EXOSC10/DUS1L	61
MF	GO:0001102	RNA polymerase II activating transcription factor binding	12/2189	53/17697	0.02607	0.4595	0.4409	FOS/TBX18/JUN/LDB1/EGR2/HEY2/EOMES/TP53BP1/RB1/SETD3/TBX2/NHLH2	12
MF	GO:0098505	G-rich strand telomeric DNA binding	4/2189	10/17697	0.02647	0.4595	0.4409	RPA2/POT1/TERF2IP/RPA1	4
MF	GO:0004386	helicase activity	29/2189	163/17697	0.02739	0.465	0.4462	DDX3X/RECQL/CHD2/DHX15/SLFN11/CHD1/SMARCA1/RAD54L/RAD50/CHD9/MCM9/BTAF1/DDX50/RAD54B/GTF2F2/DDX11/DDX39A/DDX19B/RAD54L2/SMARCA4/SETX/AQR/HELQ/CHD1L/DDX21/ERCC6L/DDX5/DHX33/WRN	29
MF	GO:0016407	acetyltransferase activity	21/2189	110/17697	0.02766	0.465	0.4462	PAFAH1B3/LPCAT1/TAF5L/KANSL1L/PHF20/NAA20/SPHK1/GNPNAT1/DPF2/KAT6A/TAF6L/DBT/KANSL1/TADA2A/TAF12/DLAT/LPCAT4/TAF5/HAT1/SUPT7L/POLE3	21
MF	GO:0033549	MAP kinase phosphatase activity	5/2189	15/17697	0.02977	0.4794	0.4601	DUSP6/DUSP1/DUSP5/DUSP3/DUSP7	5
MF	GO:1990841	promoter-specific chromatin binding	11/2189	48/17697	0.02977	0.4794	0.4601	EGR1/DNMT1/NFE2L1/FOXC2/SETDB1/ZNF304/HSF1/E2F4/NUP98/HDAC2/DDX5	11
MF	GO:0140030	modification-dependent protein binding	26/2189	144/17697	0.02995	0.4794	0.4601	IKBKE/KDM7A/ZBTB1/TNIP1/SPIN3/CHD1/PSME4/UBL7/ZFAND2B/ING4/KMT2E/FAN1/KDM4A/SPIN1/DPF2/TP53BP1/PHF1/ING1/PSMD4/TNFAIP3/SMARCA4/ZRANB1/ZFAND6/MSL3/PYGO1/BAZ2A	26
MF	GO:0050699	WW domain binding	8/2189	31/17697	0.03123	0.4794	0.4601	NDFIP2/NFE2/TCEAL3/TP63/ENAH/CDC25C/TCEAL4/WBP2NL	8
MF	GO:0140142	nucleocytoplasmic carrier activity	8/2189	31/17697	0.03123	0.4794	0.4601	KPNA2/KPNA4/SNUPN/TNPO3/IPO4/XPO1/KPNA1/RANBP6	8
MF	GO:0015144	carbohydrate transmembrane transporter activity	9/2189	37/17697	0.03307	0.4794	0.4601	SLC2A10/AQP1/SLC5A3/SLC2A11/TMEM144/SLC2A3/SLC50A1/SLC45A1/SLC23A2	9
MF	GO:0042162	telomeric DNA binding	9/2189	37/17697	0.03307	0.4794	0.4601	RAD50/APEX1/RPA2/TP53BP1/UPF2/POT1/TERF2IP/RPA1/WRN	9
MF	GO:0046332	SMAD binding	16/2189	80/17697	0.03428	0.4794	0.4601	FOS/BMP2/ZBTB7A/JUN/SMURF2/ACVR2A/DROSHA/RNF111/TGFB1I1/HMGA2/MAGI2/SNW1/PRDM16/SMAD7/ANKRD1/DDX5	16
MF	GO:0005112	Notch binding	7/2189	26/17697	0.03447	0.4794	0.4601	JAG1/ADAM17/CUL3/SNW1/NOTCH1/AAK1/KCTD10	7
MF	GO:0019903	protein phosphatase binding	25/2189	140/17697	0.0369	0.4794	0.4601	IKBKE/PPP2R2A/FBXL2/PDLIM4/AKAP11/BOD1L2/CDKN1B/MTMR3/PARD3/SLC9A1/MTMR9/PTK2/SPHK1/RPA2/MAP3K5/PHACTR4/TRAF3/PPP6R1/PPME1/DLG4/STYXL1/MYOZ2/STRN3/CTTNBP2NL/CDC27	25
MF	GO:0051184	cofactor transmembrane transporter activity	6/2189	21/17697	0.03733	0.4794	0.4601	ABCB6/SLC48A1/SLC23A2/SLC25A17/SLC25A32/SLC46A1	6
MF	GO:0005522	profilin binding	4/2189	11/17697	0.03761	0.4794	0.4601	EVL/VASP/RHOQ/ENAH	4
MF	GO:0032404	mismatch repair complex binding	4/2189	11/17697	0.03761	0.4794	0.4601	MCM9/MLH1/MUTYH/WRN	4
MF	GO:0070181	small ribosomal subunit rRNA binding	4/2189	11/17697	0.03761	0.4794	0.4601	MRPS6/MRPS18C/CIRBP/MRPS18A	4
MF	GO:0060090	molecular adaptor activity	39/2189	237/17697	0.03787	0.4794	0.4601	TRIM6/BLNK/WWC3/GRB10/CAV1/OTUD4/COX15/PEF1/SHB/HOMER1/RAD50/MPP7/SLC9A1/STX1A/VPS11/DET1/SHC1/DVL2/LAMTOR3/SH2D2A/PAG1/SH2B3/LAMTOR4/AP2A2/ARPC4/SH3BGR/AP2M1/MAP1A/FRMD4A/BICD1/VAV3/FLRT1/PDE4DIP/ISCU/CRKL/DUSP19/ARRDC1/BICD2/SPSB2	39
MF	GO:0003678	DNA helicase activity	16/2189	81/17697	0.038	0.4794	0.4601	DDX3X/RECQL/CHD2/CHD1/RAD50/CHD9/MCM9/RAD54B/GTF2F2/DDX11/RAD54L2/SETX/HELQ/CHD1L/ERCC6L/WRN	16
MF	GO:0000400	four-way junction DNA binding	5/2189	16/17697	0.03901	0.4794	0.4601	ABL1/RAD51D/HMGB2/RAD51C/WRN	5
MF	GO:0004697	protein kinase C activity	5/2189	16/17697	0.03901	0.4794	0.4601	PRKD3/PRKD1/PRKCZ/PKN3/PRKCI	5
MF	GO:0005149	interleukin-1 receptor binding	5/2189	16/17697	0.03901	0.4794	0.4601	IL1RN/TRIP6/IRAK4/IL36RN/IL36B	5
MF	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	5/2189	16/17697	0.03901	0.4794	0.4601	LOXL1/LOXL4/PNPO/MAOA/RNLS	5
MF	GO:0016881	acid-amino acid ligase activity	5/2189	16/17697	0.03901	0.4794	0.4601	TTLL1/GHDC/TTLL6/TTL/PPCS	5
MF	GO:0071837	HMG box domain binding	5/2189	16/17697	0.03901	0.4794	0.4601	MEOX1/JUN/EGR2/SP1/HOXA3	5
MF	GO:0050681	androgen receptor binding	10/2189	44/17697	0.03927	0.4794	0.4601	ZBTB7A/FOXP1/DAXX/TGFB1I1/TRIM68/SNW1/RB1/PRPF6/SMARCA4/DDX5	10
MF	GO:1901505	carbohydrate derivative transmembrane transporter activity	10/2189	44/17697	0.03927	0.4794	0.4601	SLC35D1/SLC37A4/SLC50A1/SLC35B4/SLC25A25/SLC35C1/SLC25A17/SLC35A2/SLC35E3/SLC25A4	10
MF	GO:0004721	phosphoprotein phosphatase activity	31/2189	182/17697	0.03965	0.4794	0.4601	DUSP6/PPP2R2A/DUSP1/DUSP5/MINPP1/PDP2/RNGTT/DUSP3/PTPMT1/PPP1R3E/MTMR3/PTPN12/PPM1H/PPM1B/DUSP7/DUSP28/PPP2CB/PPEF1/SBF1/UBASH3B/PPTC7/PPM1F/STYXL1/DUSP27/EYA4/MTMR7/CDC25C/PPP3CC/DUSP19/PDP1/PPM1G	31
MF	GO:0042393	histone binding	33/2189	197/17697	0.04257	0.509	0.4885	KDM7A/CHD2/ASF1A/RNF20/SPTY2D1/ANP32E/SPIN3/CHD1/HINFP/PSME4/DAXX/BCAS3/ING4/KMT2E/KDM4A/SPIN1/VPS72/TBL1XR1/DPF2/KAT6A/TP53BP1/PHF1/ING1/JAK2/CKS2/KDM1B/CKS1B/SMARCA4/WDR5B/HAT1/MSL3/PYGO1/BAZ2A	33
MF	GO:0047485	protein N-terminus binding	20/2189	109/17697	0.04499	0.517	0.4961	ARF6/ERCC6/NFE2/GLRX/DAXX/VPS25/RELA/MAP2K1/STX1A/RPA2/TBL1XR1/RBPJ/THAP7/GADD45A/SMARCA4/PDLIM5/BIRC2/EXOC5/STXBP1/TSC1	20
MF	GO:0016741	transferase activity, transferring one-carbon groups	37/2189	226/17697	0.04507	0.517	0.4961	TPMT/TRMT6/PCMT1/COMTD1/DIMT1/PRDM10/DPH5/DNMT1/COQ5/DNMT3A/SETD1B/DOT1L/METTL7B/PRMT9/SETD4/PCMTD2/AS3MT/METTL17/HEMK1/BCDIN3D/NSUN2/RRNAD1/SETDB1/METTL18/ASH2L/TRMT10C/PRDM16/HENMT1/COQ3/LCMT2/FAM98B/SUV39H2/SMYD3/TRMT1L/SETD3/TRMT2A/TRMT5	37
MF	GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors	10/2189	45/17697	0.04511	0.517	0.4961	KDM7A/HSPBAP1/TET1/ALKBH3/ALKBH5/JMJD6/FTO/P4HA3/KDM4A/EGLN3	10
MF	GO:0031625	ubiquitin protein ligase binding	46/2189	290/17697	0.04516	0.517	0.4961	TNFRSF1B/IKBKE/TANK/JUN/RNF20/EGR2/PER3/TRIB1/BID/DAXX/RELA/CCDC50/RALB/SPOPL/DET1/KDM4A/RPA2/TXNIP/GABARAPL1/TRAF1/TRAF3/UBE2N/CUL3/PRKAR1A/DBT/ATXN3/NAE1/UBASH3B/RB1/NKD2/MID1/SMAD7/BLZF1/GABARAP/TRIOBP/TRIB2/LAPTM4B/NDUFS2/SLC22A18/ARRDC1/PA2G4/PRKAR2A/PRKACA/JKAMP/TUBA1B/NLK	46