ONTOLOGY	ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	qvalue	geneID	Count
KEGG	hsa04210	Apoptosis	38/968	136/8135	2.528e-07	8.243e-05	6.787e-05	FOS/BIRC3/JUN/GADD45G/CFLAR/DDIT3/PARP2/MCL1/TNFRSF10A/PARP3/BCL2A1/BID/NFKB1/DAXX/LMNB2/PMAIP1/RELA/MAP2K1/TNFRSF10B/LMNB1/CHUK/MAP3K5/TRAF1/NRAS/TNFSF10/CASP9/GADD45A/CASP6/GADD45B/BCL2L1/PIK3CD/APAF1/TUBA4A/BIRC2/SPTA1/TUBA1B/HRAS/PIK3CA	38
KEGG	hsa05222	Small cell lung cancer	26/968	92/8135	1.577e-05	0.001837	0.001513	BIRC3/CCND1/GADD45G/ITGA2/CDK4/CDKN1B/NFKB1/RELA/PTK2/CHUK/TRAF1/TRAF3/CASP9/GADD45A/CKS2/GADD45B/BCL2L1/RB1/CKS1B/E2F3/PIK3CD/APAF1/CDKN2B/BIRC2/CDK6/PIK3CA	26
KEGG	hsa05168	Herpes simplex virus 1 infection	90/968	495/8135	1.691e-05	0.001837	0.001513	BIRC3/IKBKE/IFNGR2/ZNF610/ZFP90/ZNF480/ITGB3/ZNF441/ZNF571/ZNF624/ZNF763/ZNF267/TAP2/ZNF419/IRF3/ZNF79/ZNF33B/ZNF630/ZNF337/BID/IFNAR2/ZNF334/IFNAR1/ZNF605/NFKB1/ZNF766/DAXX/ZNF554/ZNF182/ZNF879/RELA/TYK2/ZNF717/ZNF14/ZNF548/ZNF10/SRPK1/ZNF415/SOCS3/ZNF214/ZNF426/ZNF19/CHUK/SRSF8/ZNF3/ZNF154/ZNF829/ZNF30/ZNF596/ZNF836/ZNF658/TRAF3/CASP9/ZNF133/IRAK4/ZNF304/ZNF311/JAK2/ZNF268/BCL2L1/POU2F2/ZNF383/IFNG/POU2F1/ZNF519/ZNF607/ZNF112/ZNF606/PIK3CD/APAF1/ZNF282/ZNF169/ZNF442/ZNF224/ZNF180/IL12A/ZNF529/ZNF77/ZNF132/ZNF2/ZFP28/BIRC2/ZNF141/ZNF805/ZNF135/PIK3CA/ZNF782/ZNF420/TSC1/ZNF84	90
KEGG	hsa05164	Influenza A	39/968	171/8135	3.771e-05	0.003054	0.002514	IKBKE/NLRX1/IFNGR2/KPNA2/ICAM1/CDK4/TNFRSF10A/IRF3/BID/IFNAR2/IFNAR1/NFKB1/RAE1/RELA/TYK2/MAP2K1/TNFRSF10B/SOCS3/RAB11A/CHUK/TNFSF10/TRAF3/CASP9/IRAK4/JAK2/TLR4/IFNG/XPO1/KPNA1/CCND3/PIK3CD/NFKBIB/APAF1/NUP98/IL12A/NXT1/CDK6/PIK3CA/SLC25A4	39
KEGG	hsa05220	Chronic myeloid leukemia	22/968	76/8135	4.684e-05	0.003054	0.002514	CCND1/ABL1/GADD45G/CDK4/CDKN1B/NFKB1/RELA/MAP2K1/SHC1/CHUK/NRAS/GADD45A/GADD45B/BCL2L1/RB1/E2F3/PIK3CD/CRKL/HDAC2/CDK6/HRAS/PIK3CA	22
KEGG	hsa05202	Transcriptional misregulation in cancer	42/968	193/8135	6.189e-05	0.003363	0.002769	DUSP6/SIX1/BIRC3/RUNX1T1/NUPR1/HOXA11/HOXA10/GADD45G/LDB1/DDIT3/MLLT1/BCL2A1/CDKN1B/NFKB1/ETV4/DOT1L/RELA/ETV5/BCL6/ID2/PTK2/FUT8/CDKN2C/SS18L1/TRAF1/HMGA2/NR4A3/ETV1/GADD45A/GADD45B/BCL2L1/SP1/ETV6/CEBPA/PBX1/ATF1/HDAC2/BIRC2/KLF3/CCNT1/DDX5/IGF1	42
KEGG	hsa05169	Epstein-Barr virus infection	43/968	202/8135	8.728e-05	0.004065	0.003347	MAP2K6/NFKBIE/IKBKE/CCND1/RELB/JUN/GADD45G/BLNK/HES1/NFKB2/ICAM1/TAP2/CDK4/IRF3/BID/IFNAR2/IFNAR1/CDKN1B/NFKB1/RELA/PSMC2/TYK2/CHUK/RBPJ/ADRM1/TRAF3/CASP9/IRAK4/CD44/PSMD4/GADD45A/TNFAIP3/GADD45B/SNW1/RB1/E2F3/CCND3/PIK3CD/NFKBIB/APAF1/HDAC2/CDK6/PIK3CA	43
KEGG	hsa04146	Peroxisome	22/968	82/8135	0.0001626	0.006624	0.005454	IDH1/FAR2/PEX11A/CAT/PEX11G/PEX11B/ECH1/NUDT19/PEX12/MVK/EHHADH/HMGCL/MPV17/PRDX5/PEX16/PECR/SLC25A17/PEX1/ACAA1/PXMP4/ACSL4/ACOX3	22
KEGG	hsa05224	Breast cancer	33/968	147/8135	0.0002011	0.007203	0.005931	FOS/CCND1/JUN/GADD45G/HES1/NFKB2/FZD2/FGF1/CDK4/JAG1/TCF7L2/TNFSF11/FGF7/DVL3/MAP2K1/HEY2/SHC1/FZD1/DVL2/NRAS/GADD45A/GADD45B/FGFR1/SP1/RB1/E2F3/NOTCH1/PIK3CD/CDK6/PGR/HRAS/PIK3CA/IGF1	33
KEGG	hsa04668	TNF signaling pathway	27/968	112/8135	0.000221	0.007203	0.005931	FOS/TNFRSF1B/BIRC3/MAP2K6/LIF/JUN/MMP14/CREB3L4/CFLAR/ICAM1/JAG1/TAB3/NFKB1/ATF6B/RELA/MAP2K1/SOCS3/CHUK/MAP3K5/TRAF1/TRAF3/TNFAIP3/PIK3CD/JUNB/BIRC2/PIK3CA/VEGFC	27
KEGG	hsa04110	Cell cycle	29/968	126/8135	0.0003077	0.00912	0.007509	CCND1/ABL1/DBF4/CCNB1/GADD45G/ANAPC16/CDK4/CDKN1C/CDKN1B/SMC3/ORC2/CDKN2D/CDKN2C/ORC4/TFDP2/STAG1/GADD45A/GADD45B/RB1/E2F3/CCND3/E2F4/CDC25C/RAD21/CDKN2B/HDAC2/CDK6/CDC7/CDC27	29
KEGG	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	22/968	89/8135	0.0005698	0.01548	0.01275	FOS/MAP2K6/NFKBIE/IFNGR2/JUN/CD274/NFKB1/RELA/MAP3K3/MAP2K1/CHUK/NRAS/JAK2/BATF3/TLR4/IFNG/PIK3CD/EML4/NFKBIB/PPP3CC/HRAS/PIK3CA	22
KEGG	hsa04010	MAPK signaling pathway	54/968	294/8135	0.0006575	0.01649	0.01358	FOS/DUSP6/MAP2K6/MAP4K4/DUSP1/RELB/DUSP5/RASA2/JUN/GADD45G/DDIT3/NFKB2/MKNK2/FGF1/EPHA2/DUSP3/NFKB1/DAXX/MAPKAPK5/RELA/RPS6KA3/FGF7/MAP3K3/MAP2K1/FLNC/PPM1B/DUSP7/EREG/PGF/LAMTOR3/CHUK/CACNA2D4/MAP3K5/FGFR2/ELK1/NRAS/BDNF/IRAK4/PAK2/GADD45A/GADD45B/FGFR1/MAP4K3/HSPB1/PDGFRB/GNA12/PPP3CC/CRKL/RASA1/PRKACA/HRAS/NLK/VEGFC/IGF1	54
KEGG	hsa00280	Valine, leucine and isoleucine degradation	14/968	48/8135	0.001013	0.02358	0.01942	MCCC1/IVD/BCKDHB/ALDH7A1/PCCB/ABAT/BCAT2/EHHADH/HMGCL/MCEE/AACS/DBT/ALDH6A1/ACAA1	14
KEGG	hsa04910	Insulin signaling pathway	29/968	137/8135	0.001299	0.02726	0.02245	PRKAB2/SREBF1/MKNK2/HK1/ACACB/PRKAG1/PPP1R3E/PRKCZ/MAP2K1/PCK2/SHC1/SOCS3/ELK1/NRAS/PRKCI/PRKAR1A/EIF4E/PHKB/RHOQ/PIK3CD/FLOT1/HK2/CRKL/PHKA1/PRKAR2A/PRKACA/HRAS/PIK3CA/TSC1	29
KEGG	hsa04068	FoxO signaling pathway	28/968	131/8135	0.001338	0.02726	0.02245	PRKAB2/CCND1/CCNB1/GADD45G/FBXO25/CAT/PRKAG1/CDKN1B/CDKN2D/HOMER1/BCL6/MAP2K1/PCK2/CHUK/GABARAPL1/NRAS/TNFSF10/CSNK1E/GADD45A/GADD45B/FBXO32/GABARAP/PIK3CD/CDKN2B/HRAS/NLK/PIK3CA/IGF1	28
KEGG	hsa05218	Melanoma	18/968	72/8135	0.001528	0.02931	0.02413	CCND1/GADD45G/FGF1/CDK4/FGF7/MAP2K1/NRAS/GADD45A/GADD45B/FGFR1/RB1/E2F3/PDGFRB/PIK3CD/CDK6/HRAS/PIK3CA/IGF1	18
KEGG	hsa04115	p53 signaling pathway	18/968	73/8135	0.001808	0.03209	0.02643	CCND1/CCNB1/GADD45G/CDK4/TNFRSF10A/BID/SESN2/PMAIP1/SESN3/TNFRSF10B/CASP9/GADD45A/GADD45B/BCL2L1/CCND3/APAF1/CDK6/IGF1	18
KEGG	hsa03018	RNA degradation	19/968	79/8135	0.00187	0.03209	0.02643	DCP1A/PAN2/PAN3/DIS3L/EXOSC8/CNOT6L/PARN/CNOT6/LSM6/PABPC5/PFKP/MPHOSPH6/LSM2/TTC37/PFKM/EXOSC4/LSM4/TOB2/EXOSC10	19
KEGG	hsa04064	NF-kappa B signaling pathway	23/968	104/8135	0.002187	0.03565	0.02936	BIRC3/RELB/GADD45G/BLNK/CFLAR/NFKB2/ICAM1/TAB3/CXCL12/BCL2A1/NFKB1/TNFSF11/RELA/CHUK/TRAF1/TRAF3/IRAK4/GADD45A/TNFAIP3/GADD45B/BCL2L1/TLR4/BIRC2	23
KEGG	hsa04015	Rap1 signaling pathway	39/968	210/8135	0.002885	0.0424	0.03491	MAP2K6/RASSF5/ITGB3/PRKD3/FGF1/EPHA2/PRKD1/PRKCZ/PARD3/RALB/FGF7/MAP2K1/SIPA1L1/SIPA1L3/PLCB1/PGF/FGFR2/PFN4/TIAM1/MAGI2/NRAS/EVL/PRKCI/RAPGEF6/PFN2/FGFR1/VASP/PDGFRB/PIK3CD/ENAH/SIPA1L2/VAV3/CRKL/GNAI3/HRAS/PIK3CA/VEGFC/SIPA1/IGF1	39
KEGG	hsa01250	Biosynthesis of nucleotide sugars	11/968	37/8135	0.002919	0.0424	0.03491	UAP1/UXS1/GFPT2/HK1/GNE/UAP1L1/FPGT/GNPNAT1/UGDH/HK2/PMM1	11
KEGG	hsa00640	Propanoate metabolism	10/968	32/8135	0.002991	0.0424	0.03491	BCKDHB/ACACB/ACSS3/PCCB/ABAT/EHHADH/MCEE/DBT/ALDH6A1/ACOX3	10
KEGG	hsa05162	Measles	28/968	139/8135	0.003349	0.04432	0.03649	FOS/IKBKE/CCND1/JUN/CDK4/IRF3/BID/IFNAR2/IFNAR1/CDKN1B/NFKB1/RELA/TYK2/CHUK/RAB9B/TRAF3/CASP9/IRAK4/TNFAIP3/BCL2L1/TLR4/CCND3/PIK3CD/NFKBIB/APAF1/IL12A/CDK6/PIK3CA	28
KEGG	hsa04211	Longevity regulating pathway	20/968	89/8135	0.003399	0.04432	0.03649	PRKAB2/ULK1/CREB3L4/CAT/PRKAG1/NFKB1/SESN2/ATF6B/RELA/SESN3/CAMKK2/ATG101/NRAS/EIF4E/PIK3CD/PRKACA/HRAS/PIK3CA/TSC1/IGF1	20
KEGG	hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	6/968	14/8135	0.0036	0.04514	0.03717	ST3GAL2/B4GALT3/CHST2/ST3GAL1/B3GNT2/FUT8	6
KEGG	hsa00520	Amino sugar and nucleotide sugar metabolism	13/968	49/8135	0.003835	0.04542	0.0374	UAP1/UXS1/GFPT2/HK1/GNE/UAP1L1/FPGT/GNPNAT1/UGDH/CYB5RL/HK2/CYB5R4/PMM1	13
KEGG	hsa05223	Non-small cell lung cancer	17/968	72/8135	0.003901	0.04542	0.0374	CCND1/RASSF5/GADD45G/CDK4/MAP2K1/NRAS/CASP9/KIF5B/GADD45A/GADD45B/RB1/E2F3/PIK3CD/EML4/CDK6/HRAS/PIK3CA	17
KEGG	hsa05132	Salmonella infection	44/968	249/8135	0.004287	0.04819	0.03968	FOS/BIRC3/MAP2K6/JUN/ARF6/RIPK2/FHOD1/TNFRSF10A/KPNA4/TAB3/NFKB1/TCF7L2/ARPC5L/RELA/CASP4/MAP2K1/VPS11/ARPC5/TNFRSF10B/FLNC/RHOG/TUBB4B/CHUK/PFN4/RAB9B/ARPC2/TNFSF10/IRAK4/KIF5B/PFN2/ARPC4/TLR4/MYL5/KPNA1/PIK3CD/PIK3C2B/TUBA4A/WASL/BIRC2/EXOC5/TUBA1B/HRAS/PIK3CA/TUBB3	44
KEGG	hsa01522	Endocrine resistance	21/968	98/8135	0.004938	0.05261	0.04332	FOS/CCND1/JUN/CDK4/JAG1/CDKN1B/MAP2K1/SHC1/HBEGF/PTK2/CDKN2C/NRAS/SP1/RB1/E2F3/NOTCH1/PIK3CD/PRKACA/HRAS/PIK3CA/IGF1	21
KEGG	hsa04218	Cellular senescence	30/968	156/8135	0.005003	0.05261	0.04332	MAP2K6/HIPK3/CCND1/RASSF5/CCNB1/GADD45G/CDK4/NFKB1/TRAF3IP2/RELA/HIPK1/RAD50/MAP2K1/MCU/NRAS/GADD45A/GADD45B/RB1/E2F3/CCND3/PIK3CD/E2F4/RAD9A/PPP3CC/CDKN2B/CDK6/HRAS/PIK3CA/TSC1/SLC25A4	30
KEGG	hsa04621	NOD-like receptor signaling pathway	34/968	184/8135	0.005625	0.0573	0.04718	BIRC3/IKBKE/NLRX1/TANK/JUN/RIPK2/IRF3/TAB3/IFNAR2/IFNAR1/NFKB1/PANX1/RELA/CASP4/TYK2/PLCB1/CHUK/TXNIP/GABARAPL1/MFN1/MCU/TRIP6/TP53BP1/TRAF3/IRAK4/AIM2/TNFAIP3/BCL2L1/TLR4/GABARAP/NFKBIB/BIRC2/DHX33/NAMPT	34
KEGG	hsa05212	Pancreatic cancer	17/968	76/8135	0.006967	0.06883	0.05667	CCND1/GADD45G/CDK4/NFKB1/RELA/RALB/MAP2K1/CHUK/CASP9/GADD45A/GADD45B/BCL2L1/RB1/E2F3/PIK3CD/CDK6/PIK3CA	17
KEGG	hsa04380	Osteoclast differentiation	25/968	128/8135	0.008085	0.07752	0.06383	FOSL1/FOS/MAP2K6/IFNGR2/RELB/JUN/BLNK/ITGB3/NFKB2/IFNAR2/IFNAR1/NFKB1/TNFSF11/RELA/TEC/TYK2/MAP2K1/SOCS3/CHUK/IFNG/PIK3CD/JUNB/FYN/PPP3CC/PIK3CA	25
KEGG	hsa05161	Hepatitis B	30/968	162/8135	0.008673	0.08078	0.06651	FOS/EGR3/MAP2K6/DDX3X/IKBKE/JUN/CREB3L4/EGR2/IRF3/BID/IFNAR1/NFKB1/ATF6B/RELA/TYK2/MAP2K1/CHUK/ELK1/NRAS/TRAF3/CASP9/IRAK4/JAK2/RB1/TLR4/E2F3/PIK3CD/APAF1/HRAS/PIK3CA	30
KEGG	hsa05215	Prostate cancer	20/968	97/8135	0.009306	0.08427	0.06938	CCND1/CREB3L4/CDKN1B/NFKB1/TCF7L2/RELA/ETV5/MAP2K1/CHUK/FGFR2/NRAS/CASP9/FGFR1/RB1/E2F3/PDGFRB/PIK3CD/HRAS/PIK3CA/IGF1	20
KEGG	hsa05030	Cocaine addiction	12/968	49/8135	0.01057	0.09105	0.07497	JUN/CREB3L4/NFKB1/MAOA/ATF6B/RELA/BDNF/CDK5R1/DLG4/GRM2/PRKACA/GNAI3	12
KEGG	hsa00562	Inositol phosphate metabolism	16/968	73/8135	0.01061	0.09105	0.07497	MINPP1/SYNJ2/PIP5KL1/MTMR3/PLCB1/IMPA1/INPP5F/ALDH6A1/PIP4K2A/INPP5B/PIK3CD/PIK3C2B/MTMR7/CDIPT/PIP5K1A/PIK3CA	16
KEGG	hsa04722	Neurotrophin signaling pathway	23/968	119/8135	0.01221	0.1021	0.08403	NFKBIE/ABL1/JUN/RIPK2/NFKB1/RELA/RPS6KA3/ARHGDIA/MAP3K3/MAP2K1/SHC1/MAP3K5/NRAS/BDNF/SH2B3/IRAK4/IRAK2/PIK3CD/NFKBIB/CRKL/MAGED1/HRAS/PIK3CA	23
KEGG	hsa03410	Base excision repair	9/968	33/8135	0.01257	0.1024	0.08433	PARP2/PARP3/POLL/POLB/APEX1/MPG/FEN1/MUTYH/POLE3	9
KEGG	hsa05214	Glioma	16/968	75/8135	0.01373	0.1092	0.08987	CCND1/GADD45G/CDK4/MAP2K1/SHC1/NRAS/GADD45A/GADD45B/RB1/E2F3/PDGFRB/PIK3CD/CDK6/HRAS/PIK3CA/IGF1	16
KEGG	hsa03250	Viral life cycle - HIV-1	14/968	63/8135	0.01443	0.112	0.09221	MAP1S/MLLT1/AFF4/PSIP1/VPS4A/TNPO3/FURIN/ELL/XPO1/MAP1A/BICD1/NUP153/CCNT1/BICD2	14
KEGG	hsa04810	Regulation of actin cytoskeleton	37/968	218/8135	0.01563	0.1155	0.09509	BDKRB2/BDKRB1/LIMK2/ITGB3/DIAPH2/ITGA2/DIAPH1/FGF1/CXCL12/ITGAE/ARPC5L/SLC9A1/FGF7/MAP2K1/ARPC5/PTK2/FGFR2/PFN4/TIAM1/NRAS/ARPC2/PAK2/PFN2/ARPC4/FGFR1/PIP4K2A/MYL5/PDGFRB/PIK3CD/ENAH/GNA12/VAV3/PIP5K1A/WASL/CRKL/HRAS/PIK3CA	37
KEGG	hsa05130	Pathogenic Escherichia coli infection	34/968	197/8135	0.01574	0.1155	0.09509	FOS/ABL1/JUN/MYO1H/ARF6/TNFRSF10A/TAB3/NFKB1/TJP1/ARPC5L/RELA/CASP4/ARPC5/TNFRSF10B/TUBB4B/CHUK/SEC24A/ARPC2/TNFSF10/CASP9/MYO1C/IRAK4/PAK2/ARPC4/TLR4/GNA12/NFKBIB/MYO5A/TUBA4A/FYN/SEC24B/WASL/TUBA1B/TUBB3	34
KEGG	hsa04917	Prolactin signaling pathway	15/968	70/8135	0.01607	0.1155	0.09509	FOS/CCND1/NFKB1/TNFSF11/RELA/SOCS5/MAP2K1/SHC1/SOCS3/NRAS/SOCS7/JAK2/PIK3CD/HRAS/PIK3CA	15
KEGG	hsa04150	mTOR signaling pathway	28/968	156/8135	0.01646	0.1155	0.09509	ULK1/ATP6V1E2/FZD2/GRB10/SESN2/EIF4B/FNIP2/RPS6KA3/DVL3/MAP2K1/FZD1/DVL2/LAMTOR3/CHUK/NRAS/LAMTOR4/MLST8/RICTOR/EIF4E/SEH1L/ATP6V1B2/PIK3CD/DEPTOR/RRAGC/HRAS/PIK3CA/TSC1/IGF1	28
KEGG	hsa05213	Endometrial cancer	13/968	58/8135	0.01682	0.1155	0.09509	CCND1/GADD45G/TCF7L2/MAP2K1/MLH1/ELK1/NRAS/CASP9/GADD45A/GADD45B/PIK3CD/HRAS/PIK3CA	13
KEGG	hsa04392	Hippo signaling pathway - multiple species	8/968	29/8135	0.017	0.1155	0.09509	WWTR1/MOB1B/MOB1A/AJUBA/FAT4/YAP1/CSNK1E/TEAD1	8
KEGG	hsa04390	Hippo signaling pathway	28/968	157/8135	0.01784	0.1187	0.09774	BIRC3/BMP2/CCND1/PPP2R2A/GDF5/FZD2/FGF1/WWTR1/MOB1B/TCF7L2/PRKCZ/PARD3/ID2/DVL3/FZD1/DVL2/MOB1A/AJUBA/PRKCI/PPP2CB/YAP1/CSNK1E/DLG4/NKD2/SMAD7/CCND3/BIRC2/TEAD1	28
KEGG	hsa00030	Pentose phosphate pathway	8/968	30/8135	0.02084	0.1359	0.1119	RBKS/PRPS1/RPIA/PRPS2/PFKP/PFKM/DERA/PGLS	8
KEGG	hsa04071	Sphingolipid signaling pathway	22/968	119/8135	0.02282	0.1458	0.1201	BDKRB2/PPP2R2A/S1PR3/BID/NFKB1/RELA/PRKCZ/MAP2K1/SGPP1/PLCB1/SPHK1/MAP3K5/NRAS/PPP2CB/SPTLC2/DEGS1/PIK3CD/GNA12/FYN/GNAI3/HRAS/PIK3CA	22
KEGG	hsa05210	Colorectal cancer	17/968	86/8135	0.02333	0.1463	0.1204	FOS/CCND1/JUN/GADD45G/TCF7L2/PMAIP1/RALB/MAP2K1/EREG/MLH1/NRAS/CASP9/GADD45A/GADD45B/PIK3CD/HRAS/PIK3CA	17
KEGG	hsa05221	Acute myeloid leukemia	14/968	67/8135	0.02414	0.1485	0.1223	DUSP6/CCND1/RUNX1T1/BCL2A1/NFKB1/TCF7L2/RELA/MAP2K1/CHUK/NRAS/CEBPA/PIK3CD/HRAS/PIK3CA	14
KEGG	hsa05216	Thyroid cancer	9/968	37/8135	0.02631	0.1588	0.1308	CCND1/GADD45G/TCF7L2/MAP2K1/CCDC6/NRAS/GADD45A/GADD45B/HRAS	9
KEGG	hsa03013	Nucleocytoplasmic transport	20/968	108/8135	0.02855	0.1686	0.1389	KPNA2/KPNA4/RAE1/SNUPN/THOC6/TNPO3/AHCTF1/UPF2/TMEM33/PNN/IPO4/NUP35/XPO1/DDX19B/KPNA1/SEH1L/UPF3B/NUP98/NUP153/NXT1	20
KEGG	hsa01200	Carbon metabolism	21/968	115/8135	0.02912	0.1686	0.1389	SDSL/IDH1/CAT/HK1/PHGDH/PRPS1/ACO1/PCCB/RPIA/PKM/ADPGK/MCEE/PRPS2/PFKP/IDH3A/ALDH6A1/DLAT/HK2/PFKM/PGLS/ACOX3	21
KEGG	hsa04550	Signaling pathways regulating pluripotency of stem cells	25/968	143/8135	0.03025	0.1686	0.1389	LIF/FZD2/HOXA1/PCGF3/LIFR/OTX1/ACVR2A/ID2/DVL3/MAP2K1/FZD1/DVL2/FGFR2/KAT6A/NRAS/SETDB1/JAK2/FGFR1/ID3/PIK3CD/REST/HRAS/PIK3CA/IGF1/SMAD9	25
KEGG	hsa05160	Hepatitis C	27/968	157/8135	0.03031	0.1686	0.1389	IKBKE/CCND1/PPP2R2A/CFLAR/CDK4/IRF3/BID/IFNAR2/IFNAR1/NFKB1/RELA/TYK2/MAP2K1/SOCS3/CHUK/NRAS/TRAF3/CASP9/PPP2CB/RB1/IFNG/E2F3/PIK3CD/APAF1/CDK6/HRAS/PIK3CA	27
KEGG	hsa04920	Adipocytokine signaling pathway	14/968	69/8135	0.03052	0.1686	0.1389	TNFRSF1B/NFKBIE/PRKAB2/ACACB/PRKAG1/NFKB1/RELA/PCK2/SOCS3/CAMKK2/CHUK/JAK2/NFKBIB/ACSL4	14
KEGG	hsa05166	Human T-cell leukemia virus 1 infection	36/968	222/8135	0.03198	0.1712	0.1409	FOSL1/FOS/CCND1/RELB/JUN/EGR1/CREB3L4/ANAPC16/NFKB2/ICAM1/EGR2/CDK4/NFKB1/ATF6B/RELA/POLB/MAP3K3/IL15RA/MAP2K1/CHUK/CDKN2C/ELK1/NRAS/BCL2L1/RB1/XPO1/E2F3/CCND3/PIK3CD/PPP3CC/CDKN2B/PRKACA/HRAS/PIK3CA/SLC25A4/CDC27	36
KEGG	hsa05417	Lipid and atherosclerosis	35/968	215/8135	0.03241	0.1712	0.1409	FOS/MAP2K6/IKBKE/TANK/JUN/DDIT3/ICAM1/TNFRSF10A/IRF3/BID/NFKB1/RELA/TNFRSF10B/PLCB1/PTK2/CHUK/MAP3K5/NRAS/TNFSF10/TRAF3/CASP9/IRAK4/JAK2/CASP6/BCL2L1/POU2F2/TLR4/POU2F1/PIK3CD/VAV3/APAF1/IL12A/PPP3CC/HRAS/PIK3CA	35
KEGG	hsa05135	Yersinia infection	24/968	137/8135	0.03255	0.1712	0.1409	FOS/MAP2K6/JUN/ARF6/IRF3/NFKB1/ARPC5L/RELA/RPS6KA3/MAP2K1/ARPC5/RHOG/PTK2/CHUK/ARPC2/IRAK4/ARPC4/TLR4/PIK3CD/VAV3/PIP5K1A/WASL/CRKL/PIK3CA	24
KEGG	hsa05230	Central carbon metabolism in cancer	14/968	70/8135	0.03414	0.1766	0.1454	IDH1/HK1/MAP2K1/FGFR2/PKM/NRAS/PFKP/FGFR1/PDGFRB/PIK3CD/HK2/PFKM/HRAS/PIK3CA	14
KEGG	hsa04660	T cell receptor signaling pathway	19/968	104/8135	0.03653	0.1861	0.1532	FOS/NFKBIE/JUN/CDK4/NFKB1/RELA/TEC/MAP2K1/CHUK/NRAS/PAK2/IFNG/PIK3CD/VAV3/NFKBIB/FYN/PPP3CC/HRAS/PIK3CA	19
KEGG	hsa04658	Th1 and Th2 cell differentiation	17/968	92/8135	0.04203	0.2108	0.1736	FOS/NFKBIE/IFNGR2/IL4R/JUN/JAG1/NFKB1/RELA/TYK2/CHUK/RBPJ/JAK2/IFNG/NOTCH1/NFKBIB/IL12A/PPP3CC	17
KEGG	hsa04630	JAK-STAT signaling pathway	27/968	162/8135	0.04295	0.2109	0.1736	IFNGR2/CCND1/IL4R/GHR/LIF/IL21R/MCL1/IFNAR2/IFNAR1/LIFR/SOCS5/TYK2/IL15RA/SOCS3/IL11/SOCS7/JAK2/IL22RA2/BCL2L1/IL27RA/IFNG/PDGFRB/CCND3/PIK3CD/IL12A/HRAS/PIK3CA	27
KEGG	hsa04928	Parathyroid hormone synthesis, secretion and action	19/968	106/8135	0.04334	0.2109	0.1736	FOS/EGR1/MMP14/CREB3L4/TNFSF11/ATF6B/MAP2K1/PDE4D/PLCB1/HBEGF/MEF2D/FGFR1/PTHLH/SP1/NR4A2/GNA12/VDR/PRKACA/GNAI3	19
KEGG	hsa04933	AGE-RAGE signaling pathway in diabetic complications	18/968	100/8135	0.04663	0.2208	0.1818	CCND1/JUN/EGR1/ICAM1/DIAPH1/CDK4/CDKN1B/NFKB1/RELA/PRKCZ/THBD/PLCB1/NRAS/JAK2/PIK3CD/HRAS/PIK3CA/VEGFC	18
KEGG	hsa01524	Platinum drug resistance	14/968	73/8135	0.04682	0.2208	0.1818	BIRC3/GSTO1/GSTO2/BID/PMAIP1/MLH1/MAP3K5/CASP9/BCL2L1/PIK3CD/APAF1/BIRC2/PIK3CA/MGST2	14
KEGG	hsa04144	Endocytosis	39/968	251/8135	0.04742	0.2208	0.1818	EHD1/ARF6/CHMP7/SMAP2/CAV1/SMURF2/RAB11FIP2/RAB11FIP5/ARPC5L/PIP5KL1/VPS25/PRKCZ/PARD3/ARPC5/VPS4A/AGAP1/RAB11A/FGFR2/RAB22A/ACAP2/ARPC2/VPS37A/PRKCI/KIF5B/AP2A2/ARPC4/ASAP1/DNM3/AP2M1/VPS28/STAMBP/PIP5K1A/SNX5/WASL/ZFYVE27/AGAP6/RUFY1/HRAS/VPS45	39
KEGG	hsa03440	Homologous recombination	9/968	41/8135	0.04826	0.2216	0.1824	RAD54L/RAD50/RAD51D/RPA2/RAD54B/BABAM1/RAD51C/RPA1/TOPBP1	9
KEGG	hsa05208	Chemical carcinogenesis - reactive oxygen species	35/968	223/8135	0.05136	0.2325	0.1915	FOS/ABL1/JUN/PRKD3/CAT/GSTO1/NDUFV2/GSTO2/PRKD1/NDUFA6/NFKB1/NDUFB5/RELA/PPIF/AS3MT/MAP2K1/PTK2/CHUK/COX1/MAP3K5/AKR1A1/NRAS/SLC26A1/NDUFS3/PIK3CD/UQCR10/CBR1/NDUFV1/NDUFS2/NDUFB10/NDUFA11/HRAS/PIK3CA/MGST2/SLC25A4	35
KEGG	hsa05142	Chagas disease	18/968	102/8135	0.05502	0.2457	0.2023	BDKRB2/FOS/IFNGR2/PPP2R2A/JUN/CFLAR/NFKB1/RELA/PLCB1/CHUK/IRAK4/PPP2CB/TLR4/IFNG/PIK3CD/IL12A/GNAI3/PIK3CA	18
KEGG	hsa04662	B cell receptor signaling pathway	15/968	82/8135	0.05807	0.2558	0.2106	FOS/NFKBIE/JUN/BLNK/NFKB1/RELA/MAP2K1/CHUK/NRAS/PIK3CD/VAV3/NFKBIB/PPP3CC/HRAS/PIK3CA	15
KEGG	hsa03450	Non-homologous end-joining	4/968	13/8135	0.05914	0.257	0.2116	POLL/RAD50/FEN1/LIG4	4
KEGG	hsa05203	Viral carcinogenesis	32/968	204/8135	0.06073	0.2605	0.2145	EGR3/DDX3X/CCND1/RASA2/JUN/CREB3L4/NFKB2/EGR2/CDK4/IRF3/CDKN1B/NFKB1/PMAIP1/ATF6B/RELA/POLB/RBPJ/TRAF1/PKM/NRAS/TRAF3/SNW1/RB1/CCND3/PIK3CD/HNRNPK/CDKN2B/HDAC2/CDK6/PRKACA/HRAS/PIK3CA	32
KEGG	hsa05207	Chemical carcinogenesis - receptor activation	33/968	212/8135	0.06282	0.266	0.219	FOS/IKBKE/CCND1/KPNA2/JUN/CREB3L4/GSTO1/JAG1/KPNA4/GSTO2/NFKB1/TNFSF11/ATF6B/RELA/BCL6/RPS6KA3/FGF7/MAP2K1/NRAS/JAK2/RB1/PAQR5/KPNA1/CCND3/PIK3CD/KLF5/VDR/PGR/PRKACA/GNAI3/HRAS/PIK3CA/MGST2	33
KEGG	hsa04935	Growth hormone synthesis, secretion and action	20/968	119/8135	0.06871	0.2785	0.2293	FOS/MAP2K6/GHR/CREB3L4/ATF6B/MAP2K1/SHC1/PLCB1/SOCS3/PTK2/NRAS/JAK2/PIK3CD/JUNB/CRKL/PRKACA/GNAI3/HRAS/PIK3CA/IGF1	20
KEGG	hsa04932	Non-alcoholic fatty liver disease	25/968	155/8135	0.06892	0.2785	0.2293	FOS/PRKAB2/SREBF1/JUN/DDIT3/NDUFV2/PRKAG1/MLX/BID/NDUFA6/NFKB1/NDUFB5/RELA/SOCS3/COX1/MAP3K5/CEBPA/NDUFS3/PIK3CD/UQCR10/NDUFV1/NDUFS2/NDUFB10/NDUFA11/PIK3CA	25
KEGG	hsa04934	Cushing syndrome	25/968	155/8135	0.06892	0.2785	0.2293	RASD1/CCND1/CREB3L4/FZD2/CDK4/CDKN1B/TCF7L2/ATF6B/DVL3/MAP2K1/PLCB1/FZD1/DVL2/CDKN2C/ASH2L/SP1/RB1/E2F3/PBX1/WDR5B/CDKN2B/CDK6/NCEH1/PRKACA/GNAI3	25
KEGG	hsa05145	Toxoplasmosis	19/968	112/8135	0.06919	0.2785	0.2293	BIRC3/MAP2K6/IFNGR2/NFKB1/RELA/PPIF/TYK2/CHUK/CASP9/IRAK4/JAK2/IRGM/BCL2L1/TLR4/IFNG/NFKBIB/IL12A/BIRC2/GNAI3	19
KEGG	hsa04012	ErbB signaling pathway	15/968	85/8135	0.07516	0.2988	0.246	ABL1/JUN/CDKN1B/MAP2K1/SHC1/HBEGF/EREG/PTK2/ELK1/NRAS/PAK2/PIK3CD/CRKL/HRAS/PIK3CA	15
KEGG	hsa04215	Apoptosis - multiple species	7/968	32/8135	0.07803	0.3037	0.25	BIRC3/BID/PMAIP1/CASP9/BCL2L1/APAF1/BIRC2	7
KEGG	hsa05167	Kaposi sarcoma-associated herpesvirus infection	30/968	194/8135	0.07849	0.3037	0.25	FOS/MAP2K6/IKBKE/CCND1/JUN/ICAM1/CDK4/GNG11/IRF3/BID/IFNAR2/IFNAR1/NFKB1/TCF7L2/RELA/TYK2/MAP2K1/CHUK/NRAS/TRAF3/CASP9/JAK2/RB1/E2F3/PIK3CD/PREX1/PPP3CC/CDK6/HRAS/PIK3CA	30
KEGG	hsa03022	Basal transcription factors	9/968	45/8135	0.0798	0.3037	0.25	TAF5L/GTF2IRD1/GTF2F2/TAF6L/TAF12/GTF2I/GTF2H5/TAF5/TAF4B	9
KEGG	hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	5/968	20/8135	0.08011	0.3037	0.25	CHST7/CHST14/CSGALNACT2/CHST15/CHST12	5
KEGG	hsa05163	Human cytomegalovirus infection	34/968	225/8135	0.0832	0.3118	0.2567	MAP2K6/PTGER2/CCND1/CREB3L4/ITGB3/TAP2/CDK4/GNG11/IRF3/CXCL12/BID/NFKB1/ATF6B/RELA/MAP2K1/PLCB1/PTK2/CHUK/ELK1/NRAS/CASP9/SP1/RB1/E2F3/PIK3CD/GNA12/PPP3CC/CRKL/CDK6/PRKACA/GNAI3/HRAS/PIK3CA/TSC1	34
KEGG	hsa04330	Notch signaling pathway	11/968	59/8135	0.08565	0.3137	0.2583	HES1/JAG1/TLE3/ADAM17/DVL3/HEY2/DVL2/RBPJ/SNW1/NOTCH1/HDAC2	11
KEGG	hsa04370	VEGF signaling pathway	11/968	59/8135	0.08565	0.3137	0.2583	MAP2K1/PTK2/SPHK1/SH2D2A/NRAS/CASP9/HSPB1/PIK3CD/PPP3CC/HRAS/PIK3CA	11
KEGG	hsa00051	Fructose and mannose metabolism	7/968	33/8135	0.08936	0.3237	0.2665	HK1/ENOSF1/FPGT/PFKP/HK2/PFKM/PMM1	7
KEGG	hsa01040	Biosynthesis of unsaturated fatty acids	6/968	27/8135	0.09323	0.3309	0.2724	ACOT7/ELOVL7/ELOVL6/ACAA1/ELOVL4/ACOX3	6
KEGG	hsa00010	Glycolysis / Gluconeogenesis	12/968	67/8135	0.09526	0.3309	0.2724	MINPP1/HK1/ALDH7A1/PCK2/GALM/AKR1A1/PKM/ADPGK/PFKP/DLAT/HK2/PFKM	12
KEGG	hsa00770	Pantothenate and CoA biosynthesis	5/968	21/8135	0.09531	0.3309	0.2724	PPCDC/BCAT2/PANK1/ENPP1/PPCS	5
KEGG	hsa05225	Hepatocellular carcinoma	26/968	168/8135	0.0954	0.3309	0.2724	CCND1/GADD45G/FZD2/CDK4/GSTO1/GSTO2/TCF7L2/DVL3/MAP2K1/SHC1/FZD1/DVL2/ELK1/NRAS/ARID1B/GADD45A/GADD45B/BCL2L1/RB1/E2F3/PIK3CD/SMARCA4/CDK6/HRAS/PIK3CA/MGST2	26
KEGG	hsa05418	Fluid shear stress and atherosclerosis	22/968	139/8135	0.0982	0.337	0.2775	FOS/MAP2K6/DUSP1/JUN/ITGB3/ICAM1/CAV1/GSTO1/GSTO2/NFKB1/RELA/PRKCZ/THBD/ACVR2A/PTK2/SDC4/CHUK/MAP3K5/IFNG/PIK3CD/PIK3CA/MGST2	22
KEGG	hsa01230	Biosynthesis of amino acids	13/968	75/8135	0.1038	0.3526	0.2903	SDSL/IDH1/ARG2/PHGDH/PRPS1/ACO1/RPIA/BCAT2/PKM/PRPS2/PFKP/IDH3A/PFKM	13
KEGG	hsa05219	Bladder cancer	8/968	41/8135	0.1069	0.3566	0.2936	CCND1/CDK4/MAP2K1/HBEGF/NRAS/RB1/E2F3/HRAS	8
KEGG	hsa04620	Toll-like receptor signaling pathway	17/968	104/8135	0.1074	0.3566	0.2936	FOS/MAP2K6/IKBKE/JUN/IRF3/IFNAR2/IFNAR1/NFKB1/RELA/MAP2K1/CHUK/TRAF3/IRAK4/TLR4/PIK3CD/IL12A/PIK3CA	17
KEGG	hsa04070	Phosphatidylinositol signaling system	16/968	97/8135	0.109	0.3566	0.2936	SYNJ2/MTMR3/PPIP5K1/PLCB1/IMPA1/PPIP5K2/IMPAD1/INPP5F/PIP4K2A/INPP5B/PIK3CD/PIK3C2B/MTMR7/CDIPT/PIP5K1A/PIK3CA	16
KEGG	hsa04140	Autophagy - animal	22/968	141/8135	0.1102	0.3566	0.2936	ULK1/TANK/CFLAR/MTMR3/ATG4C/MAP2K1/CAMKK2/ATG101/GABARAPL1/NRAS/MLST8/PPP2CB/BCL2L1/GABARAP/PIK3CD/DEPTOR/PRKACA/RRAGC/HRAS/PIK3CA/TSC1/RAB39B	22
KEGG	hsa05165	Human papillomavirus infection	47/968	331/8135	0.1105	0.3566	0.2936	IKBKE/CCND1/PPP2R2A/CREB3L4/ATP6V1E2/ITGB3/ITGA2/HES1/FZD2/CDK4/JAG1/IRF3/IFNAR2/IFNAR1/CDKN1B/NFKB1/TCF7L2/HES4/RELA/PRKCZ/PARD3/TYK2/DVL3/MAP2K1/HEY2/FZD1/PTK2/DVL2/CHUK/RBPJ/PKM/NRAS/TRAF3/PRKCI/PPP2CB/RB1/NOTCH1/PDGFRB/ATP6V1B2/CCND3/PIK3CD/HDAC2/CDK6/PRKACA/HRAS/PIK3CA/TSC1	47
KEGG	hsa05226	Gastric cancer	23/968	149/8135	0.1139	0.3639	0.2996	CCND1/GADD45G/FZD2/FGF1/CDKN1B/TCF7L2/FGF7/DVL3/MAP2K1/SHC1/FZD1/MLH1/DVL2/FGFR2/NRAS/GADD45A/GADD45B/RB1/E2F3/PIK3CD/CDKN2B/HRAS/PIK3CA	23
KEGG	hsa05100	Bacterial invasion of epithelial cells	13/968	77/8135	0.1213	0.384	0.3161	CAV1/ARPC5L/ARPC5/SHC1/RHOG/PTK2/ARPC2/ARPC4/DNM3/PIK3CD/WASL/CRKL/PIK3CA	13
KEGG	hsa00310	Lysine degradation	11/968	63/8135	0.1228	0.3848	0.3168	GCDH/ALDH7A1/SETD1B/DOT1L/KMT2E/HYKK/EHHADH/SETDB1/PRDM16/SUV39H2/SMYD3	11
KEGG	hsa04360	Axon guidance	27/968	182/8135	0.1322	0.4104	0.3379	ABL1/EPHB3/LIMK2/SLIT2/EPHA2/CXCL12/PRKCZ/PARD3/BOC/PTK2/NRAS/SEMA7A/RYK/PAK2/SRGAP1/MYL5/EPHB2/PIK3CD/ENAH/SEMA4G/FYN/PPP3CC/EPHA4/RASA1/GNAI3/HRAS/PIK3CA	27
KEGG	hsa00130	Ubiquinone and other terpenoid-quinone biosynthesis	3/968	11/8135	0.1339	0.411	0.3384	COQ5/COQ7/COQ3	3
KEGG	hsa00450	Selenocompound metabolism	4/968	17/8135	0.1349	0.411	0.3384	PSTK/SEPHS2/MARS2/SEPHS1	4
KEGG	hsa05016	Huntington disease	43/968	306/8135	0.1373	0.4144	0.3412	ULK1/CREB3L4/TFAM/NDUFV2/NDUFA6/DNAL1/NDUFB5/PPIF/PSMC2/STX1A/POLR2I/PLCB1/TUBB4B/COX1/ATG101/MAP3K5/DNAL4/BDNF/ADRM1/CASP9/PSMD4/KIF5B/AP2A2/DLG4/SP1/POLR2G/AP2M1/NDUFS3/UQCR10/APAF1/REST/TUBA4A/NDUFV1/NDUFS2/GPX7/HDAC2/GPX8/TAF4B/NDUFB10/NDUFA11/TUBA1B/TUBB3/SLC25A4	43
KEGG	hsa00630	Glyoxylate and dicarboxylate metabolism	6/968	30/8135	0.1386	0.4144	0.3412	CAT/ACO1/PCCB/MCEE/GRHPR/HOGA1	6
KEGG	hsa04350	TGF-beta signaling pathway	15/968	94/8135	0.1446	0.4275	0.352	BMP2/GDF5/FST/SMURF2/ACVR2A/ID2/PPP2CB/GREM2/SP1/IFNG/SMAD7/ID3/E2F4/CDKN2B/SMAD9	15
KEGG	hsa04530	Tight junction	25/968	169/8135	0.1463	0.4275	0.352	PRKAB2/CCND1/PPP2R2A/AMOTL1/JUN/CDK4/PRKAG1/TJP1/ARPC5L/PRKCZ/PARD3/ARPC5/MAP3K5/TIAM1/MYL6B/ARPC2/PRKCI/PPP2CB/RAPGEF6/ARPC4/VASP/RAB8B/TUBA4A/PRKACA/TUBA1B	25
KEGG	hsa04066	HIF-1 signaling pathway	17/968	109/8135	0.1469	0.4275	0.352	IFNGR2/MKNK2/HK1/CDKN1B/NFKB1/RELA/MAP2K1/EGLN3/PFKP/EIF4E/TLR4/IFNG/PIK3CD/HK2/PFKM/PIK3CA/IGF1	17
KEGG	hsa00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	5/968	24/8135	0.1487	0.4291	0.3533	GLCE/HS2ST1/EXT1/EXTL2/HS3ST3A1	5
KEGG	hsa00410	beta-Alanine metabolism	6/968	31/8135	0.1556	0.4409	0.363	SMOX/ALDH7A1/ABAT/EHHADH/ALDH6A1/ACOX3	6
KEGG	hsa04510	Focal adhesion	29/968	201/8135	0.1559	0.4409	0.363	BIRC3/CCND1/JUN/ITGB3/ITGA2/DIAPH1/CAV1/MAP2K1/SHC1/FLNC/PTK2/PGF/ZYX/ELK1/PAK2/VASP/MYL5/PDGFRB/CCND3/PIK3CD/VAV3/FYN/PIP5K1A/CRKL/BIRC2/HRAS/PIK3CA/VEGFC/IGF1	29
KEGG	hsa04014	Ras signaling pathway	33/968	232/8135	0.1569	0.4409	0.363	ABL1/RASA2/RASSF5/ARF6/FGF1/GNG11/EPHA2/NFKB1/RELA/RALB/FGF7/MAP2K1/SHC1/PGF/CHUK/FGFR2/ELK1/TIAM1/NRAS/BDNF/PAK2/BCL2L1/FGFR1/PDGFRB/PIK3CD/PLA2G12A/RGL2/RASA1/PRKACA/HRAS/PIK3CA/VEGFC/IGF1	33
KEGG	hsa04936	Alcoholic liver disease	21/968	142/8135	0.1718	0.4718	0.3884	MAP2K6/IKBKE/PRKAB2/CCND1/SREBF1/IRF3/TAB3/ACACB/PRKAG1/ALDH7A1/NFKB1/TCF7L2/RELA/CAMKK2/CHUK/MAP3K5/TRAF3/IRAK4/TLR4/IL12A/ACOX3	21
KEGG	hsa04961	Endocrine and other factor-regulated calcium reabsorption	9/968	53/8135	0.1727	0.4718	0.3884	BDKRB2/ATP2B1/PLCB1/RAB11A/AP2A2/DNM3/AP2M1/VDR/PRKACA	9
KEGG	hsa04136	Autophagy - other	6/968	32/8135	0.1735	0.4718	0.3884	ATG4C/ATG101/GABARAPL1/MLST8/PPP2CB/GABARAP	6
KEGG	hsa04666	Fc gamma R-mediated phagocytosis	15/968	97/8135	0.1737	0.4718	0.3884	LIMK2/ARF6/ARPC5L/MAP2K1/ARPC5/SPHK1/ARPC2/ARPC4/ASAP1/VASP/PIK3CD/VAV3/PIP5K1A/CRKL/PIK3CA	15
KEGG	hsa04152	AMPK signaling pathway	18/968	120/8135	0.1783	0.4804	0.3956	PRKAB2/CCND1/PPP2R2A/ULK1/SREBF1/CREB3L4/ACACB/PRKAG1/ELAVL1/PCK2/CAMKK2/PPP2CB/PFKP/PIK3CD/PFKM/PIK3CA/TSC1/IGF1	18
KEGG	hsa04151	PI3K-Akt signaling pathway	48/968	354/8135	0.1824	0.4818	0.3967	CCND1/PPP2R2A/IL4R/GHR/CREB3L4/ITGB3/ITGA2/MCL1/FGF1/CDK4/GNG11/EPHA2/IFNAR2/IFNAR1/CDKN1B/NFKB1/EIF4B/ATF6B/RELA/FGF7/MAP2K1/PCK2/EREG/PTK2/PGF/CHUK/FGFR2/MAGI2/NRAS/BDNF/CASP9/PKN3/MLST8/PPP2CB/JAK2/EIF4E/BCL2L1/FGFR1/TLR4/PDGFRB/CCND3/PIK3CD/CDK6/HRAS/PIK3CA/VEGFC/TSC1/IGF1	48
KEGG	hsa01210	2-Oxocarboxylic acid metabolism	4/968	19/8135	0.1825	0.4818	0.3967	IDH1/ACO1/BCAT2/IDH3A	4
KEGG	hsa05205	Proteoglycans in cancer	29/968	205/8135	0.1833	0.4818	0.3967	CCND1/TWIST2/ITGB3/ITGA2/FZD2/CAV1/EIF4B/SLC9A1/MAP2K1/DROSHA/FLNC/FZD1/HBEGF/PTK2/SDC4/PLAUR/ELK1/TIAM1/NRAS/CD44/FGFR1/TLR4/PIK3CD/VAV3/PRKACA/HRAS/DDX5/PIK3CA/IGF1	29
KEGG	hsa04919	Thyroid hormone signaling pathway	18/968	121/8135	0.1877	0.4895	0.403	CCND1/MED30/ITGB3/SLC9A1/MAP2K1/PLCB1/NRAS/CASP9/MED16/PFKP/NOTCH1/THRA/PIK3CD/PFKM/HDAC2/PRKACA/HRAS/PIK3CA	18
KEGG	hsa00620	Pyruvate metabolism	8/968	47/8135	0.1898	0.491	0.4043	ACACB/ALDH7A1/PCK2/AKR1A1/PKM/ACYP1/DLAT/GRHPR	8
KEGG	hsa00260	Glycine, serine and threonine metabolism	7/968	40/8135	0.1917	0.4922	0.4053	SDSL/PHGDH/ALDH7A1/MAOA/ALAS1/DMGDH/GRHPR	7
KEGG	hsa04213	Longevity regulating pathway - multiple species	10/968	62/8135	0.1971	0.5019	0.4133	PRKAB2/CAT/PRKAG1/NRAS/PIK3CD/HDAC2/PRKACA/HRAS/PIK3CA/IGF1	10
KEGG	hsa05140	Leishmaniasis	12/968	77/8135	0.2	0.5023	0.4136	FOS/IFNGR2/JUN/NFKB1/RELA/ELK1/IRAK4/JAK2/TLR4/IFNG/NFKBIB/IL12A	12
KEGG	hsa01240	Biosynthesis of cofactors	22/968	153/8135	0.2003	0.5023	0.4136	PNPO/LIAS/COQ5/COX15/MMAB/GCH1/ALAS1/PPCDC/BCAT2/PANK1/PHOSPHO2/AKR1A1/UGDH/RFK/COQ7/CPOX/DHRS3/COQ3/NME3/NME6/PMM1/PPCS	22
KEGG	hsa05131	Shigellosis	34/968	247/8135	0.2038	0.5072	0.4176	JUN/TNIP1/DIAPH1/ARF6/RIPK2/HK1/IRF3/TAB3/NFKB1/ARPC5L/U2AF1L4/RELA/CASP4/ARPC5/PLCB1/PTK2/CHUK/PFN4/ARPC2/CD44/UBE2N/PFN2/ARPC4/BCL2L1/TLR4/MYL5/PIK3CD/NFKBIB/TECPR1/HK2/WASL/CRKL/RRAGC/PIK3CA	34
KEGG	hsa04622	RIG-I-like receptor signaling pathway	11/968	70/8135	0.2055	0.5075	0.4179	DDX3X/IKBKE/NLRX1/TANK/IRF3/NFKB1/RELA/CHUK/TRAF3/NFKBIB/IL12A	11
KEGG	hsa04931	Insulin resistance	16/968	108/8135	0.2099	0.511	0.4208	PRKAB2/SREBF1/CREB3L4/GFPT2/ACACB/PRKAG1/MLX/NFKB1/PPP1R3E/RELA/PRKCZ/RPS6KA3/PCK2/SOCS3/PIK3CD/PIK3CA	16
KEGG	hsa04623	Cytosolic DNA-sensing pathway	10/968	63/8135	0.2111	0.511	0.4208	IKBKE/IRF3/NFKB1/RELA/CHUK/POLR3K/AIM2/POLR1C/POLR3C/NFKBIB	10
KEGG	hsa03020	RNA polymerase	6/968	34/8135	0.2116	0.511	0.4208	POLR1E/POLR2I/POLR3K/POLR1C/POLR2G/POLR3C	6
KEGG	hsa04340	Hedgehog signaling pathway	9/968	56/8135	0.2167	0.5194	0.4277	CCND1/SMURF2/SPOPL/BOC/CUL3/CSNK1E/MGRN1/HHAT/PRKACA	9
KEGG	hsa04657	IL-17 signaling pathway	14/968	94/8135	0.2236	0.5321	0.4382	FOSL1/FOS/IKBKE/JUN/CCL7/TAB3/NFKB1/TRAF3IP2/ELAVL1/RELA/CHUK/TRAF3/TNFAIP3/IFNG	14
KEGG	hsa01521	EGFR tyrosine kinase inhibitor resistance	12/968	79/8135	0.2255	0.5327	0.4386	MAP2K1/SHC1/FGFR2/NRAS/JAK2/EIF4E/BCL2L1/PDGFRB/PIK3CD/HRAS/PIK3CA/IGF1	12
KEGG	hsa05134	Legionellosis	9/968	57/8135	0.2322	0.542	0.4463	NFKB2/CLK4/NFKB1/RELA/CASP9/TLR4/HSF1/APAF1/IL12A	9
KEGG	hsa04137	Mitophagy - animal	11/968	72/8135	0.2328	0.542	0.4463	ULK1/JUN/RELA/GABARAPL1/MFN1/NRAS/BCL2L1/SP1/USP30/GABARAP/HRAS	11
KEGG	hsa00650	Butanoate metabolism	5/968	28/8135	0.2347	0.5426	0.4467	ALDH5A1/ABAT/EHHADH/HMGCL/AACS	5
KEGG	hsa05014	Amyotrophic lateral sclerosis	48/968	364/8135	0.2409	0.553	0.4554	TNFRSF1B/MAP2K6/ULK1/TANK/DDIT3/VAPB/CAT/NDUFV2/BID/NDUFA6/DNAL1/DAXX/NDUFB5/RAE1/PSMC2/TUBB4B/COX1/ATG101/MAP3K5/PFN4/MCU/DNAL4/ADRM1/CASP9/PSMD4/KIF5B/PFN2/BCL2L1/NUP35/SEH1L/NDUFS3/UQCR10/APAF1/NUP98/SETX/TUBA4A/NDUFV1/NUP153/NDUFS2/PPP3CC/GPX7/GPX8/NXT1/NDUFB10/NDUFA11/TUBA1B/TUBB3/RAB39B	48
KEGG	hsa00071	Fatty acid degradation	7/968	43/8135	0.2458	0.5604	0.4614	GCDH/ECI1/ALDH7A1/EHHADH/ACAA1/ACSL4/ACOX3	7
KEGG	hsa04625	C-type lectin receptor signaling pathway	15/968	104/8135	0.2516	0.5672	0.4671	EGR3/IKBKE/RELB/JUN/NFKB2/EGR2/NFKB1/RELA/CHUK/NRAS/PIK3CD/IL12A/PPP3CC/HRAS/PIK3CA	15
KEGG	hsa00512	Mucin type O-glycan biosynthesis	6/968	36/8135	0.2523	0.5672	0.4671	ST3GAL2/ST3GAL1/GCNT3/B4GALT5/GALNT15/ST6GALNAC1	6
KEGG	hsa00270	Cysteine and methionine metabolism	8/968	51/8135	0.2564	0.5724	0.4713	SDSL/MTAP/DNMT1/LACC1/PHGDH/DNMT3A/BCAT2/MPST	8
KEGG	hsa00603	Glycosphingolipid biosynthesis - globo and isoglobo series	3/968	15/8135	0.2611	0.579	0.4767	ST3GAL2/ST3GAL1/GBGT1	3
KEGG	hsa05010	Alzheimer disease	50/968	384/8135	0.2656	0.585	0.4817	ULK1/DDIT3/FZD2/SLC39A14/NDUFV2/BID/NDUFA6/NFKB1/NDUFB5/RELA/PPIF/PSMC2/RTN3/ADAM17/DVL3/MAP2K1/PLCB1/FZD1/TUBB4B/DVL2/CHUK/COX1/ATG101/MAP3K5/MCU/NRAS/ADRM1/CASP9/PSMD4/CDK5R1/KIF5B/CSNK1E/NAE1/SLC39A10/NDUFS3/PIK3CD/UQCR10/APAF1/TUBA4A/NDUFV1/NDUFS2/PPP3CC/SLC11A2/NDUFB10/NDUFA11/TUBA1B/HRAS/PIK3CA/TUBB3/SLC25A4	50
KEGG	hsa04926	Relaxin signaling pathway	18/968	129/8135	0.2705	0.588	0.4841	FOS/JUN/CREB3L4/GNG11/NFKB1/ATF6B/RELA/PRKCZ/MAP2K1/SHC1/PLCB1/NRAS/PIK3CD/PRKACA/GNAI3/HRAS/PIK3CA/VEGFC	18
KEGG	hsa04714	Thermogenesis	31/968	232/8135	0.2705	0.588	0.4841	PRKAB2/CREB3L4/NDUFV2/COX15/PRKAG1/COA5/NDUFA6/NDUFB5/RPS6KA3/COX1/MAP3K5/KDM3B/NRAS/COX11/MLST8/NDUFAF3/NDUFAF4/ARID1B/FGFR1/PRDM16/NDUFS3/UQCR10/SMARCA4/NDUFV1/NDUFS2/PRKACA/NDUFB10/NDUFA11/HRAS/ACSL4/TSC1	31
KEGG	hsa05416	Viral myocarditis	9/968	60/8135	0.2811	0.6007	0.4946	CCND1/ABL1/SGCD/ICAM1/CAV1/BID/EIF4G3/CASP9/FYN	9
KEGG	hsa00020	Citrate cycle (TCA cycle)	5/968	30/8135	0.2819	0.6007	0.4946	IDH1/ACO1/PCK2/IDH3A/DLAT	5
KEGG	hsa01523	Antifolate resistance	5/968	30/8135	0.2819	0.6007	0.4946	ABCC5/NFKB1/RELA/CHUK/SLC46A1	5
KEGG	hsa05012	Parkinson disease	35/968	266/8135	0.2863	0.606	0.499	DUSP1/DDIT3/SLC39A14/NDUFV2/NDUFA6/MAOA/DAXX/NDUFB5/PPIF/PSMC2/TUBB4B/COX1/MAP3K5/MFN1/MCU/ADRM1/CASP9/PSMD4/KIF5B/BCL2L1/SLC39A10/NDUFS3/UQCR10/APAF1/TUBA4A/NDUFV1/NDUFS2/SLC11A2/PRKACA/NDUFB10/NDUFA11/TUBA1B/GNAI3/TUBB3/SLC25A4	35
KEGG	hsa00515	Mannose type O-glycan biosynthesis	4/968	23/8135	0.2898	0.6095	0.5018	B4GALT3/FUT4/CHST10/POMGNT1	4
KEGG	hsa04650	Natural killer cell mediated cytotoxicity	18/968	131/8135	0.2931	0.6125	0.5043	IFNGR2/ICAM1/TNFRSF10A/BID/IFNAR2/IFNAR1/MAP2K1/TNFRSF10B/SHC1/NRAS/TNFSF10/IFNG/PIK3CD/VAV3/FYN/PPP3CC/HRAS/PIK3CA	18
KEGG	hsa04659	Th17 cell differentiation	15/968	108/8135	0.3012	0.6163	0.5074	FOS/NFKBIE/IFNGR2/IL4R/IL21R/JUN/NFKB1/RELA/TYK2/CHUK/JAK2/IL27RA/IFNG/NFKBIB/PPP3CC	15
KEGG	hsa05211	Renal cell carcinoma	10/968	69/8135	0.3026	0.6163	0.5074	JUN/EPAS1/MAP2K1/EGLN3/NRAS/PAK2/PIK3CD/CRKL/HRAS/PIK3CA	10
KEGG	hsa04930	Type II diabetes mellitus	7/968	46/8135	0.3039	0.6163	0.5074	HK1/PRKCZ/SOCS3/PKM/PIK3CD/HK2/PIK3CA	7
KEGG	hsa05170	Human immunodeficiency virus 1 infection	28/968	212/8135	0.3056	0.6163	0.5074	FOS/TNFRSF1B/MAP2K6/JUN/CCNB1/LIMK2/TAP2/GNG11/IRF3/BID/NFKB1/RELA/MAP2K1/PTK2/CHUK/NRAS/CASP9/IRAK4/PAK2/BCL2L1/TLR4/PIK3CD/CDC25C/PPP3CC/CRKL/GNAI3/HRAS/PIK3CA	28
KEGG	hsa00052	Galactose metabolism	5/968	31/8135	0.3062	0.6163	0.5074	HK1/GALM/PFKP/HK2/PFKM	5
KEGG	hsa04710	Circadian rhythm	5/968	31/8135	0.3062	0.6163	0.5074	PRKAB2/PER3/PRKAG1/CSNK1E/CRY1	5
KEGG	hsa01232	Nucleotide metabolism	12/968	85/8135	0.3088	0.617	0.508	NT5E/GMPR2/LACC1/IMPDH2/ADA/PNP/AMPD3/ENPP1/UCK1/NME3/NME6/DCTD	12
KEGG	hsa03460	Fanconi anemia pathway	8/968	54/8135	0.3104	0.617	0.508	HES1/FANCF/FAN1/MLH1/RPA2/POLI/RAD51C/RPA1	8
KEGG	hsa00513	Various types of N-glycan biosynthesis	6/968	39/8135	0.3167	0.6258	0.5153	ALG13/B4GALT3/FUT8/MAN1B1/MAN2A1/B4GALNT3	6
KEGG	hsa04914	Progesterone-mediated oocyte maturation	14/968	102/8135	0.3262	0.6403	0.5272	CCNB1/ANAPC16/RPS6KA3/MAP2K1/PIK3CD/CPEB1/CDC25C/STK10/PGR/PRKACA/GNAI3/PIK3CA/CDC27/IGF1	14
KEGG	hsa04120	Ubiquitin mediated proteolysis	19/968	142/8135	0.328	0.6403	0.5272	BIRC3/UBE2H/ANAPC16/UBE4B/SMURF2/RHOBTB1/UBE2Q2/DET1/SOCS3/UBE2N/CUL3/UBE2S/MID1/UBA2/MGRN1/SAE1/BIRC2/HERC1/CDC27	19
KEGG	hsa05217	Basal cell carcinoma	9/968	63/8135	0.3325	0.6452	0.5312	BMP2/GADD45G/FZD2/TCF7L2/DVL3/FZD1/DVL2/GADD45A/GADD45B	9
KEGG	hsa00920	Sulfur metabolism	2/968	10/8135	0.3378	0.6482	0.5337	MPST/IMPAD1	2
KEGG	hsa04310	Wnt signaling pathway	22/968	167/8135	0.338	0.6482	0.5337	FOSL1/CCND1/JUN/FZD2/TLE3/TCF7L2/DVL3/CTNND2/PLCB1/FZD1/DVL2/TBL1XR1/CBY1/RYK/CSNK1E/NKD2/CCND3/ROR2/PPP3CC/DAAM2/PRKACA/NLK	22
KEGG	hsa05020	Prion disease	35/968	273/8135	0.3437	0.6553	0.5396	EGR1/CREB3L4/DDIT3/CAV1/NDUFV2/NDUFA6/NDUFB5/ATF6B/PPIF/PSMC2/TUBB4B/COX1/MCU/ADRM1/CASP9/PSMD4/KIF5B/NOTCH1/NDUFS3/PIK3CD/UQCR10/APAF1/TUBA4A/FYN/NDUFV1/NDUFS2/PPP3CC/STIP1/PRKACA/NDUFB10/NDUFA11/TUBA1B/PIK3CA/TUBB3/SLC25A4	35
KEGG	hsa04540	Gap junction	12/968	88/8135	0.3532	0.6695	0.5512	TJP1/MAP2K1/PLCB1/TUBB4B/NRAS/PDGFRB/TUBA4A/PRKACA/TUBA1B/GNAI3/HRAS/TUBB3	12
KEGG	hsa00061	Fatty acid biosynthesis	3/968	18/8135	0.3638	0.6848	0.5639	ACACB/HSD17B8/ACSL4	3
KEGG	hsa01212	Fatty acid metabolism	8/968	57/8135	0.3664	0.6848	0.5639	ELOVL7/HSD17B8/EHHADH/ELOVL6/ACAA1/ELOVL4/ACSL4/ACOX3	8
KEGG	hsa05321	Inflammatory bowel disease	9/968	65/8135	0.3676	0.6848	0.5639	IFNGR2/IL4R/IL21R/JUN/NFKB1/RELA/TLR4/IFNG/IL12A	9
KEGG	hsa00563	Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	4/968	26/8135	0.3748	0.6887	0.5671	MPPE1/PIGC/PIGB/PIGV	4
KEGG	hsa00790	Folate biosynthesis	4/968	26/8135	0.3748	0.6887	0.5671	GCH1/PCBD2/QDPR/CBR1	4
KEGG	hsa04915	Estrogen signaling pathway	18/968	138/8135	0.3761	0.6887	0.5671	FOS/JUN/CREB3L4/KRT16/ATF6B/MAP2K1/SHC1/PLCB1/HBEGF/NRAS/SP1/PIK3CD/EBAG9/PGR/PRKACA/GNAI3/HRAS/PIK3CA	18
KEGG	hsa03040	Spliceosome	19/968	147/8135	0.3865	0.7039	0.5796	DHX15/SNRNP27/RBM22/ZMAT2/U2AF1L4/SRSF8/LSM6/RBM25/RP9/SNW1/CTNNBL1/PRPF6/LSM2/AQR/HNRNPK/LSM4/PRPF4/SRSF10/DDX5	19
KEGG	hsa00062	Fatty acid elongation	4/968	27/8135	0.4032	0.7302	0.6012	ACOT7/ELOVL7/ELOVL6/ELOVL4	4
KEGG	hsa04730	Long-term depression	8/968	60/8135	0.4232	0.7559	0.6224	MAP2K1/PLCB1/NRAS/PPP2CB/GNA12/GNAI3/HRAS/IGF1	8
KEGG	hsa00600	Sphingolipid metabolism	7/968	52/8135	0.4256	0.7559	0.6224	SGPP1/SPHK1/NEU1/KDSR/B4GALT6/SPTLC2/DEGS1	7
KEGG	hsa04912	GnRH signaling pathway	12/968	93/8135	0.429	0.7559	0.6224	MAP2K6/JUN/EGR1/MMP14/MAP3K3/MAP2K1/PLCB1/HBEGF/ELK1/NRAS/PRKACA/HRAS	12
KEGG	hsa03030	DNA replication	5/968	36/8135	0.4298	0.7559	0.6224	PRIM1/RPA2/FEN1/RPA1/POLE3	5
KEGG	hsa04062	Chemokine signaling pathway	24/968	192/8135	0.4309	0.7559	0.6224	CCL7/GNG11/CXCL12/NFKB1/RELA/PRKCZ/PARD3/MAP2K1/SHC1/PLCB1/PTK2/CHUK/TIAM1/NRAS/JAK2/PIK3CD/PREX1/VAV3/NFKBIB/CRKL/PRKACA/GNAI3/HRAS/PIK3CA	24
KEGG	hsa04217	Necroptosis	20/968	159/8135	0.4313	0.7559	0.6224	BIRC3/IFNGR2/CFLAR/CHMP7/SPATA2L/TNFRSF10A/BID/IFNAR2/IFNAR1/TYK2/VPS4A/TNFRSF10B/TNFSF10/JAK2/TNFAIP3/TLR4/IFNG/USP21/BIRC2/SLC25A4	20
KEGG	hsa05031	Amphetamine addiction	9/968	69/8135	0.4386	0.7646	0.6296	FOS/JUN/CREB3L4/MAOA/ATF6B/STX1A/PPP3CC/HDAC2/PRKACA	9
KEGG	hsa05022	Pathways of neurodegeneration - multiple diseases	58/968	476/8135	0.4437	0.7694	0.6335	TNFRSF1B/MAP2K6/ULK1/TANK/DDIT3/FZD2/VAPB/CAT/NDUFV2/BID/NDUFA6/NFKB1/DNAL1/DAXX/NDUFB5/RELA/PPIF/PSMC2/DVL3/MAP2K1/STX1A/PLCB1/FZD1/TUBB4B/DVL2/COX1/ATG101/MAP3K5/MFN1/MCU/DNAL4/NRAS/BDNF/ADRM1/CASP9/PSMD4/CDK5R1/KIF5B/CSNK1E/ATXN3/BCL2L1/DLG4/NDUFS3/UQCR10/APAF1/TUBA4A/NDUFV1/NDUFS2/PPP3CC/GPX7/GPX8/NDUFB10/NDUFA11/TUBA1B/HRAS/TUBB3/RAB39B/SLC25A4	58
KEGG	hsa05143	African trypanosomiasis	5/968	37/8135	0.4543	0.7829	0.6446	ICAM1/F2RL1/PLCB1/IFNG/IL12A	5
KEGG	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	9/968	70/8135	0.4563	0.7829	0.6446	JUN/ATP6V1E2/NFKB1/TJP1/RELA/ADAM17/HBEGF/CHUK/ATP6V1B2	9
KEGG	hsa03015	mRNA surveillance pathway	12/968	97/8135	0.4895	0.8355	0.688	PPP2R2A/RNGTT/PABPC5/PPP2CB/UPF2/PNN/PCF11/GSPT1/DDX19B/UPF3B/PELO/NXT1	12
KEGG	hsa04973	Carbohydrate digestion and absorption	6/968	47/8135	0.4935	0.8378	0.6898	HK1/PLCB1/SLC37A4/PIK3CD/HK2/PIK3CA	6
KEGG	hsa00900	Terpenoid backbone biosynthesis	3/968	22/8135	0.496	0.8378	0.6898	MVK/NUS1/MVD	3
KEGG	hsa04072	Phospholipase D signaling pathway	18/968	148/8135	0.4987	0.838	0.69	ARF6/PTGFR/RALB/MAP2K1/SHC1/PLCB1/SPHK1/NRAS/DNM3/GRM2/PDGFRB/PIK3CD/GNA12/FYN/PIP5K1A/HRAS/PIK3CA/TSC1	18
KEGG	hsa05231	Choline metabolism in cancer	12/968	98/8135	0.5045	0.8434	0.6944	FOS/JUN/MAP2K1/NRAS/SP1/PDGFRB/SLC22A5/PIK3CD/PIP5K1A/HRAS/PIK3CA/TSC1	12
KEGG	hsa04922	Glucagon signaling pathway	13/968	107/8135	0.5129	0.853	0.7024	PRKAB2/CREB3L4/ACACB/PRKAG1/PCK2/PLCB1/PKM/PFKP/PHKB/PPP3CC/PFKM/PHKA1/PRKACA	13
KEGG	hsa04022	cGMP-PKG signaling pathway	20/968	167/8135	0.524	0.8672	0.714	BDKRB2/ATP2B1/CREB3L4/GTF2IRD1/ATF6B/PPIF/MRVI1/KCNMB3/MAP2K1/PLCB1/MEF2D/RGS2/VASP/GTF2I/GNA12/PPP3CC/GNAI3/KCNJ8/NPR2/SLC25A4	20
KEGG	hsa03430	Mismatch repair	3/968	23/8135	0.5269	0.8676	0.7143	MLH1/RPA2/RPA1	3
KEGG	hsa05017	Spinocerebellar ataxia	17/968	143/8135	0.5409	0.8854	0.729	ULK1/PPIF/PSMC2/PLCB1/RBPJ/ATG101/MAP3K5/MCU/ADRM1/PSMD4/FGF14/ATXN3/SP1/OMA1/PIK3CD/PIK3CA/SLC25A4	17
KEGG	hsa00480	Glutathione metabolism	7/968	58/8135	0.5447	0.8854	0.729	IDH1/GSTO1/GSTO2/LANCL1/GPX7/GPX8/MGST2	7
KEGG	hsa00604	Glycosphingolipid biosynthesis - ganglio series	2/968	15/8135	0.5478	0.8854	0.729	ST3GAL2/ST3GAL1	2
KEGG	hsa04916	Melanogenesis	12/968	101/8135	0.5486	0.8854	0.729	CREB3L4/FZD2/TCF7L2/DVL3/MAP2K1/PLCB1/FZD1/DVL2/NRAS/PRKACA/GNAI3/HRAS	12
KEGG	hsa00510	N-Glycan biosynthesis	6/968	50/8135	0.5564	0.8902	0.7329	ALG13/B4GALT3/FUT8/MAN1B1/MAN2A1/MGAT5	6
KEGG	hsa05133	Pertussis	9/968	76/8135	0.5594	0.8902	0.7329	FOS/JUN/IRF3/NFKB1/RELA/IRAK4/TLR4/IL12A/GNAI3	9
KEGG	hsa05146	Amoebiasis	12/968	102/8135	0.563	0.8902	0.7329	ARG2/NFKB1/RELA/PLCB1/PTK2/TLR4/IFNG/HSPB1/PIK3CD/IL12A/PRKACA/PIK3CA	12
KEGG	hsa00230	Purine metabolism	15/968	128/8135	0.5667	0.8902	0.7329	HDDC3/NT5E/GMPR2/LACC1/PRPS1/IMPDH2/ADA/PDE4D/PNP/AMPD3/ENPP1/PRPS2/NME3/NME6/NPR2	15
KEGG	hsa04664	Fc epsilon RI signaling pathway	8/968	68/8135	0.57	0.8902	0.7329	MAP2K6/MAP2K1/NRAS/PIK3CD/VAV3/FYN/HRAS/PIK3CA	8
KEGG	hsa04921	Oxytocin signaling pathway	18/968	154/8135	0.5704	0.8902	0.7329	FOS/PRKAB2/CCND1/JUN/PRKAG1/MAP2K1/PLCB1/CAMKK2/CACNA2D4/ELK1/NRAS/MYL6B/RGS2/PPP3CC/PRKACA/GNAI3/HRAS/NPR2	18
KEGG	hsa00380	Tryptophan metabolism	5/968	42/8135	0.5707	0.8902	0.7329	GCDH/CAT/ALDH7A1/MAOA/EHHADH	5
KEGG	hsa00330	Arginine and proline metabolism	6/968	51/8135	0.5766	0.8951	0.737	SMOX/ARG2/ALDH7A1/MAOA/P4HA3/HOGA1	6
KEGG	hsa00430	Taurine and hypotaurine metabolism	2/968	16/8135	0.5838	0.9003	0.7413	ADO/FMO2	2
KEGG	hsa00592	alpha-Linolenic acid metabolism	3/968	25/8135	0.5855	0.9003	0.7413	PLA2G12A/ACAA1/ACOX3	3
KEGG	hsa04721	Synaptic vesicle cycle	9/968	78/8135	0.592	0.9044	0.7446	ATP6V1E2/STX1A/SLC1A1/AP2A2/DNM3/ATP6V1B2/AP2M1/SLC6A1/STXBP1	9
KEGG	hsa04725	Cholinergic synapse	13/968	113/8135	0.5958	0.9044	0.7446	FOS/CREB3L4/GNG11/MAP2K1/PLCB1/NRAS/JAK2/PIK3CD/FYN/PRKACA/GNAI3/HRAS/PIK3CA	13
KEGG	hsa04371	Apelin signaling pathway	16/968	139/8135	0.5964	0.9044	0.7446	PRKAB2/CCND1/EGR1/TFAM/GNG11/JAG1/PRKAG1/SLC9A1/MAP2K1/PLCB1/SPHK1/MEF2D/NRAS/PRKACA/GNAI3/HRAS	16
KEGG	hsa04520	Adherens junction	8/968	71/8135	0.6206	0.9367	0.7712	TCF7L2/YES1/TJP1/PARD3/FGFR1/FYN/WASL/NLK	8
KEGG	hsa04750	Inflammatory mediator regulation of TRP channels	11/968	98/8135	0.6291	0.9452	0.7782	BDKRB2/BDKRB1/MAP2K6/PTGER2/F2RL1/PLCB1/TRPA1/PIK3CD/PRKACA/PIK3CA/IGF1	11
KEGG	hsa00760	Nicotinate and nicotinamide metabolism	4/968	36/8135	0.6352	0.9498	0.7821	NT5E/PNP/ENPP1/NAMPT	4
KEGG	hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	3/968	27/8135	0.6392	0.9514	0.7834	B4GALT3/B3GNT2/FUT4	3
KEGG	hsa03050	Proteasome	5/968	46/8135	0.6537	0.9619	0.792	PSME4/PSMC2/ADRM1/PSMD4/IFNG	5
KEGG	hsa00250	Alanine, aspartate and glutamate metabolism	4/968	37/8135	0.6571	0.9619	0.792	GFPT2/ALDH5A1/ABAT/NIT2	4
KEGG	hsa04960	Aldosterone-regulated sodium reabsorption	4/968	37/8135	0.6571	0.9619	0.792	PIK3CD/NR3C2/PIK3CA/IGF1	4
KEGG	hsa03008	Ribosome biogenesis in eukaryotes	12/968	109/8135	0.658	0.9619	0.792	RPP25L/NVL/WDR36/DROSHA/RIOK1/NOP10/XPO1/UTP15/GNL2/RCL1/SPATA5/NXT1	12
KEGG	hsa04927	Cortisol synthesis and secretion	7/968	65/8135	0.6684	0.9728	0.801	CREB3L4/ATF6B/PLCB1/SP1/PBX1/NCEH1/PRKACA	7
KEGG	hsa03420	Nucleotide excision repair	5/968	47/8135	0.6728	0.9748	0.8026	ERCC6/RPA2/RPA1/GTF2H5/POLE3	5
KEGG	hsa05340	Primary immunodeficiency	4/968	38/8135	0.6781	0.9782	0.8054	BLNK/TAP2/RFXAP/ADA	4
KEGG	hsa05323	Rheumatoid arthritis	10/968	93/8135	0.6821	0.9795	0.8065	FOS/JUN/ATP6V1E2/ICAM1/CXCL12/TNFSF11/IL11/TLR4/IFNG/ATP6V1B2	10
KEGG	hsa04720	Long-term potentiation	7/968	67/8135	0.6997	0.9979	0.8216	RPS6KA3/MAP2K1/PLCB1/NRAS/PPP3CC/PRKACA/HRAS	7
KEGG	hsa00240	Pyrimidine metabolism	6/968	58/8135	0.7033	0.9979	0.8216	NT5E/ENPP1/UCK1/NME3/NME6/DCTD	6
KEGG	hsa04114	Oocyte meiosis	14/968	131/8135	0.707	0.9979	0.8216	SLK/CCNB1/ANAPC16/SMC3/RPS6KA3/MAP2K1/PPP2CB/CPEB1/CDC25C/PPP3CC/PGR/PRKACA/CDC27/IGF1	14
KEGG	hsa00565	Ether lipid metabolism	5/968	49/8135	0.7088	0.9979	0.8216	PAFAH1B3/LPCAT1/ENPP6/PLA2G12A/LPCAT4	5
KEGG	hsa00053	Ascorbate and aldarate metabolism	3/968	30/8135	0.7102	0.9979	0.8216	ALDH7A1/AKR1A1/UGDH	3
KEGG	hsa04979	Cholesterol metabolism	5/968	50/8135	0.7258	1	0.8234	VAPB/ANGPTL4/APOC3/VAPA/NCEH1	5
KEGG	hsa04978	Mineral absorption	6/968	60/8135	0.7343	1	0.8234	ATP2B1/STEAP1/CLCN2/SLC46A1/VDR/SLC11A2	6
KEGG	hsa00190	Oxidative phosphorylation	14/968	134/8135	0.7384	1	0.8234	ATP6V1E2/NDUFV2/COX15/NDUFA6/NDUFB5/COX1/COX11/ATP6V1B2/NDUFS3/UQCR10/NDUFV1/NDUFS2/NDUFB10/NDUFA11	14
KEGG	hsa04060	Cytokine-cytokine receptor interaction	32/968	295/8135	0.7414	1	0.8234	TNFRSF1B/BMP2/IFNGR2/IL4R/GHR/LIF/IL21R/GDF5/IL1RN/CCL7/TNFRSF10A/CLCF1/CXCL12/ACKR3/IFNAR2/CD27/IFNAR1/LIFR/TNFSF11/TNFRSF10D/ACVR2A/IL15RA/TNFRSF10B/IL11/TNFSF15/TNFSF10/TNFRSF12A/IL27RA/IFNG/IL36RN/IL12A/IL36B	32
KEGG	hsa00564	Glycerophospholipid metabolism	10/968	98/8135	0.7443	1	0.8234	GPD2/ETNK1/LPCAT1/LCLAT1/GPD1L/GPAM/PLA2G12A/LPCAT4/CDIPT/LYPLA2	10
KEGG	hsa04925	Aldosterone synthesis and secretion	10/968	98/8135	0.7443	1	0.8234	ATP2B1/CREB3L4/PRKD3/PRKD1/ATF6B/PLCB1/DAGLB/NR4A2/ATF1/PRKACA	10
KEGG	hsa00983	Drug metabolism - other enzymes	8/968	80/8135	0.7511	1	0.8234	TPMT/GSTO1/GSTO2/IMPDH2/UCK1/NME3/NME6/MGST2	8
KEGG	hsa00340	Histidine metabolism	2/968	22/8135	0.7558	1	0.8234	ALDH7A1/MAOA	2
KEGG	hsa00860	Porphyrin metabolism	4/968	43/8135	0.7695	1	0.8234	COX15/MMAB/ALAS1/CPOX	4
KEGG	hsa04130	SNARE interactions in vesicular transport	3/968	33/8135	0.7699	1	0.8234	STX6/STX1A/VAMP4	3
KEGG	hsa03060	Protein export	2/968	23/8135	0.7776	1	0.8234	IMMP1L/OXA1L	2
KEGG	hsa04614	Renin-angiotensin system	2/968	23/8135	0.7776	1	0.8234	AGTR2/PREP	2
KEGG	hsa04964	Proximal tubule bicarbonate reclamation	2/968	23/8135	0.7776	1	0.8234	AQP1/PCK2	2
KEGG	hsa04962	Vasopressin-regulated water reabsorption	4/968	44/8135	0.7851	1	0.8234	CREB3L4/ARHGDIA/RAB11A/PRKACA	4
KEGG	hsa05415	Diabetic cardiomyopathy	21/968	203/8135	0.7861	1	0.8234	GFPT2/NDUFV2/PDK2/NDUFA6/NFKB1/NDUFB5/RELA/PPIF/PRKCZ/PLCB1/COX1/SP1/NDUFS3/PIK3CD/UQCR10/NDUFV1/NDUFS2/NDUFB10/NDUFA11/PIK3CA/SLC25A4	21
KEGG	hsa00040	Pentose and glucuronate interconversions	3/968	34/8135	0.7874	1	0.8234	DCXR/AKR1A1/UGDH	3
KEGG	hsa04929	GnRH secretion	6/968	64/8135	0.7893	1	0.8234	MAP2K1/PLCB1/NRAS/PIK3CD/HRAS/PIK3CA	6
KEGG	hsa04977	Vitamin digestion and absorption	2/968	24/8135	0.7976	1	0.8234	SLC19A2/SLC46A1	2
KEGG	hsa02010	ABC transporters	4/968	45/8135	0.7999	1	0.8234	ABCC5/TAP2/ABCB6/ABCB10	4
KEGG	hsa03320	PPAR signaling pathway	7/968	75/8135	0.8046	1	0.8234	ANGPTL4/PCK2/APOC3/EHHADH/ACAA1/ACSL4/ACOX3	7
KEGG	hsa04918	Thyroid hormone synthesis	7/968	75/8135	0.8046	1	0.8234	CREB3L4/ATF6B/PLCB1/SLC26A4/GPX7/GPX8/PRKACA	7
KEGG	hsa04670	Leukocyte transendothelial migration	11/968	114/8135	0.8123	1	0.8234	RASSF5/ICAM1/CXCL12/PTK2/VASP/MYL5/PIK3CD/VAV3/GNAI3/PIK3CA/SIPA1	11
KEGG	hsa00970	Aminoacyl-tRNA biosynthesis	6/968	66/8135	0.8134	1	0.8234	PSTK/VARS2/DARS2/HARS2/MARS2/LARS2	6
KEGG	hsa00500	Starch and sucrose metabolism	3/968	36/8135	0.8192	1	0.8234	HK1/ENPP1/HK2	3
KEGG	hsa00514	Other types of O-glycan biosynthesis	4/968	47/8135	0.8269	1	0.8234	B4GALT3/EOGT/GALNT15/GXYLT2	4
KEGG	hsa04950	Maturity onset diabetes of the young	2/968	26/8135	0.833	1	0.8234	HES1/NKX2-2	2
KEGG	hsa04924	Renin secretion	6/968	69/8135	0.8453	1	0.8234	PTGER2/AQP1/PLCB1/PPP3CC/PRKACA/GNAI3	6
KEGG	hsa04727	GABAergic synapse	8/968	89/8135	0.8465	1	0.8234	GNG11/ABAT/GABARAPL1/GABARAP/SLC38A2/SLC6A1/PRKACA/GNAI3	8
KEGG	hsa04966	Collecting duct acid secretion	2/968	27/8135	0.8485	1	0.8234	ATP6V1E2/ATP6V1B2	2
KEGG	hsa05410	Hypertrophic cardiomyopathy	8/968	90/8135	0.855	1	0.8234	PRKAB2/SGCD/ITGB3/ITGA2/PRKAG1/CACNA2D4/ACTC1/IGF1	8
KEGG	hsa05110	Vibrio cholerae infection	4/968	50/8135	0.8617	1	0.8234	ATP6V1E2/TJP1/ATP6V1B2/PRKACA	4
KEGG	hsa05144	Malaria	4/968	50/8135	0.8617	1	0.8234	ICAM1/TLR4/IFNG/IL12A	4
KEGG	hsa00360	Phenylalanine metabolism	1/968	16/8135	0.8685	1	0.8234	MAOA	1
KEGG	hsa04728	Dopaminergic synapse	12/968	132/8135	0.8756	1	0.8234	FOS/PPP2R2A/CREB3L4/GNG11/MAOA/ATF6B/PLCB1/PPP2CB/KIF5B/PPP3CC/PRKACA/GNAI3	12
KEGG	hsa05152	Tuberculosis	17/968	180/8135	0.8762	1	0.8234	IFNGR2/RIPK2/BID/NFKB1/RELA/RFXAP/SPHK1/CASP9/IRAK4/JAK2/TLR4/IFNG/IRAK2/APAF1/IL12A/PPP3CC/VDR	17
KEGG	hsa04216	Ferroptosis	3/968	41/8135	0.8814	1	0.8234	SLC39A14/SLC11A2/ACSL4	3
KEGG	hsa04724	Glutamatergic synapse	10/968	114/8135	0.8856	1	0.8234	GNG11/HOMER1/SLC1A1/PLCB1/DLG4/GRM2/SLC38A2/PPP3CC/PRKACA/GNAI3	10
KEGG	hsa04611	Platelet activation	11/968	124/8135	0.8864	1	0.8234	ITGB3/ITGA2/PRKCZ/PLCB1/PRKCI/VASP/PIK3CD/FYN/PRKACA/GNAI3/PIK3CA	11
KEGG	hsa04726	Serotonergic synapse	10/968	115/8135	0.8917	1	0.8234	DUSP1/GNG11/MAOA/MAP2K1/PLCB1/NRAS/HTR1D/PRKACA/GNAI3/HRAS	10
KEGG	hsa00511	Other glycan degradation	1/968	18/8135	0.898	1	0.8234	NEU1	1
KEGG	hsa04911	Insulin secretion	7/968	86/8135	0.9	1	0.8234	CREB3L4/ATF6B/KCNMB3/STX1A/PLCB1/CCKAR/PRKACA	7
KEGG	hsa04940	Type I diabetes mellitus	3/968	43/8135	0.9003	1	0.8234	IFNG/IL12A/ICA1	3
KEGG	hsa04723	Retrograde endocannabinoid signaling	13/968	148/8135	0.9094	1	0.8234	GNG11/NDUFV2/NDUFA6/NDUFB5/PLCB1/DAGLB/NDUFS3/NDUFV1/NDUFS2/PRKACA/NDUFB10/NDUFA11/GNAI3	13
KEGG	hsa04923	Regulation of lipolysis in adipocytes	4/968	56/8135	0.9137	1	0.8234	PIK3CD/PRKACA/GNAI3/PIK3CA	4
KEGG	hsa04261	Adrenergic signaling in cardiomyocytes	13/968	150/8135	0.9184	1	0.8234	ATP2B1/PPP2R2A/CREB3L4/ATF6B/SLC9A1/PLCB1/CACNA2D4/ACTC1/PPP2CB/AGTR2/PRKACA/CREM/GNAI3	13
KEGG	hsa04061	Viral protein interaction with cytokine and cytokine receptor	8/968	100/8135	0.9209	1	0.8234	TNFRSF1B/CCL7/TNFRSF10A/CXCL12/ACKR3/TNFRSF10D/TNFRSF10B/TNFSF10	8
KEGG	hsa00100	Steroid biosynthesis	1/968	20/8135	0.9209	1	0.8234	FDFT1	1
KEGG	hsa04141	Protein processing in endoplasmic reticulum	15/968	171/8135	0.9236	1	0.8234	EDEM3/DDIT3/HSPH1/RNF185/UBE4B/ATF6B/FBXO6/SEC24A/MAP3K5/SEC31B/ATXN3/TRAM1L1/MAN1B1/SIL1/SEC24B	15
KEGG	hsa04020	Calcium signaling pathway	22/968	240/8135	0.9276	1	0.8234	BDKRB2/BDKRB1/ATP2B1/PTGFR/FGF1/STIM2/ORAI3/PPIF/FGF7/PLCB1/SPHK1/FGFR2/MCU/CCKAR/FGFR1/PHKB/PDGFRB/PPP3CC/PHKA1/PRKACA/VEGFC/SLC25A4	22
KEGG	hsa00220	Arginine biosynthesis	1/968	22/8135	0.9386	1	0.8234	ARG2	1
KEGG	hsa00350	Tyrosine metabolism	2/968	36/8135	0.9391	1	0.8234	GSTZ1/MAOA	2
KEGG	hsa00982	Drug metabolism - cytochrome P450	5/968	72/8135	0.9411	1	0.8234	GSTO1/GSTO2/MAOA/FMO2/MGST2	5
KEGG	hsa00561	Glycerolipid metabolism	4/968	61/8135	0.9428	1	0.8234	ALDH7A1/LCLAT1/AKR1A1/GPAM	4
KEGG	hsa00590	Arachidonic acid metabolism	4/968	61/8135	0.9428	1	0.8234	PLA2G12A/CBR1/GPX7/GPX8	4
KEGG	hsa05414	Dilated cardiomyopathy	7/968	96/8135	0.9491	1	0.8234	SGCD/ITGB3/ITGA2/CACNA2D4/ACTC1/PRKACA/IGF1	7
KEGG	hsa05330	Allograft rejection	2/968	38/8135	0.9506	1	0.8234	IFNG/IL12A	2
KEGG	hsa04713	Circadian entrainment	7/968	97/8135	0.9526	1	0.8234	FOS/RASD1/PER3/GNG11/PLCB1/PRKACA/GNAI3	7
KEGG	hsa04024	cAMP signaling pathway	19/968	221/8135	0.9549	1	0.8234	FOS/PTGER2/ATP2B1/JUN/CREB3L4/NFKB1/RELA/SLC9A1/MAP2K1/PDE4D/TIAM1/BDNF/PIK3CD/VAV3/HTR1D/PRKACA/GNAI3/ACOX3/PIK3CA	19
KEGG	hsa04260	Cardiac muscle contraction	6/968	87/8135	0.956	1	0.8234	SLC9A1/CACNA2D4/COX1/ACTC1/UQCR10/SLC9A7	6
KEGG	hsa05171	Coronavirus disease - COVID-19	20/968	232/8135	0.9573	1	0.8234	FOS/IKBKE/JUN/IRF3/IFNAR2/IFNAR1/RPS24/NFKB1/RELA/TYK2/ADAM17/HBEGF/CHUK/TRAF3/IRAK4/TLR4/PIK3CD/NFKBIB/IL12A/PIK3CA	20
KEGG	hsa05206	MicroRNAs in cancer	28/968	310/8135	0.9576	1	0.8234	CCND1/ABL1/SPRY2/FOXP1/ITGB3/MCL1/DNMT1/DNMT3A/CDKN1B/NFKB1/MAP2K1/SHC1/HMGA2/NRAS/CD44/TP63/E2F3/NOTCH1/PDGFRB/PIK3CD/CDC25C/HNRNPK/CRKL/HDAC2/CDK6/HRAS/PIK3CA/BCL2L2	28
KEGG	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	5/968	77/8135	0.9603	1	0.8234	SGCD/ITGB3/ITGA2/TCF7L2/CACNA2D4	5
KEGG	hsa05204	Chemical carcinogenesis - DNA adducts	4/968	69/8135	0.9714	1	0.8234	GSTO1/GSTO2/CBR1/MGST2	4
KEGG	hsa00591	Linoleic acid metabolism	1/968	29/8135	0.9748	1	0.8234	PLA2G12A	1
KEGG	hsa04744	Phototransduction	1/968	29/8135	0.9748	1	0.8234	SLC24A1	1
KEGG	hsa04610	Complement and coagulation cascades	5/968	85/8135	0.9795	1	0.8234	BDKRB2/BDKRB1/THBD/SERPINB2/PLAUR	5
KEGG	hsa05034	Alcoholism	14/968	187/8135	0.9823	1	0.8234	CREB3L4/GNG11/MAOA/ATF6B/MAP2K1/SHC1/CAMKK2/NRAS/BDNF/HDAC2/HAT1/PRKACA/GNAI3/HRAS	14
KEGG	hsa04640	Hematopoietic cell lineage	6/968	99/8135	0.9828	1	0.8234	IL4R/ITGB3/ITGA2/IL11/CD44/CD24	6
KEGG	hsa04270	Vascular smooth muscle contraction	9/968	134/8135	0.9836	1	0.8234	MRVI1/KCNMB3/MAP2K1/PLCB1/MYL6B/GNA12/PLA2G12A/PRKACA/NPR2	9
KEGG	hsa04512	ECM-receptor interaction	5/968	88/8135	0.9842	1	0.8234	ITGB3/ITGA2/SDC4/CD44/FRAS1	5
KEGG	hsa04971	Gastric acid secretion	4/968	76/8135	0.9848	1	0.8234	SLC9A1/PLCB1/PRKACA/GNAI3	4
KEGG	hsa04672	Intestinal immune network for IgA production	2/968	49/8135	0.9849	1	0.8234	CXCL12/IL15RA	2
KEGG	hsa03010	Ribosome	11/968	158/8135	0.9856	1	0.8234	RPS24/MRPS6/MRPS18C/MRPL17/MRPS14/MRPS18A/MRPL11/MRPL10/MRPS16/MRPL24/MRPL2	11
KEGG	hsa04972	Pancreatic secretion	6/968	102/8135	0.9865	1	0.8234	ATP2B1/SLC9A1/PLCB1/RAB11A/CCKAR/PLA2G12A	6
KEGG	hsa00980	Metabolism of xenobiotics by cytochrome P450	4/968	78/8135	0.9873	1	0.8234	GSTO1/GSTO2/CBR1/MGST2	4
KEGG	hsa04913	Ovarian steroidogenesis	2/968	51/8135	0.9879	1	0.8234	PRKACA/IGF1	2
KEGG	hsa04145	Phagosome	10/968	152/8135	0.9899	1	0.8234	ATP6V1E2/ITGB3/ITGA2/TAP2/TUBB4B/TLR4/ATP6V1B2/TUBA4A/TUBA1B/TUBB3	10
KEGG	hsa00830	Retinol metabolism	3/968	68/8135	0.9908	1	0.8234	RDH10/PNPLA4/DHRS3	3
KEGG	hsa04142	Lysosome	8/968	132/8135	0.9919	1	0.8234	CTNS/NEU1/DNASE2/AP3M2/LAPTM4B/SLC11A2/CLN3/ACP2	8
KEGG	hsa04613	Neutrophil extracellular trap formation	13/968	190/8135	0.9927	1	0.8234	ITGB3/NFKB1/RELA/PPIF/CASP4/MAP2K1/PLCB1/TLR4/PIK3CD/HDAC2/HAT1/PIK3CA/SLC25A4	13
KEGG	hsa04742	Taste transduction	4/968	86/8135	0.994	1	0.8234	PLCB1/HTR1D/PRKACA/CALHM1	4
KEGG	hsa05332	Graft-versus-host disease	1/968	42/8135	0.9952	1	0.8234	IFNG	1
KEGG	hsa04976	Bile secretion	4/968	89/8135	0.9955	1	0.8234	AQP1/SLC9A1/NCEH1/PRKACA	4
KEGG	hsa04975	Fat digestion and absorption	1/968	43/8135	0.9958	1	0.8234	PLA2G12A	1
KEGG	hsa05032	Morphine addiction	4/968	91/8135	0.9963	1	0.8234	GNG11/PDE4D/PRKACA/GNAI3	4
KEGG	hsa04612	Antigen processing and presentation	3/968	78/8135	0.9967	1	0.8234	TAP2/RFXAP/IFNG	3
KEGG	hsa04970	Salivary secretion	4/968	93/8135	0.997	1	0.8234	ATP2B1/SLC9A1/PLCB1/PRKACA	4
KEGG	hsa00140	Steroid hormone biosynthesis	1/968	61/8135	0.9996	1	0.8234	HSD17B8	1
KEGG	hsa04974	Protein digestion and absorption	3/968	103/8135	0.9998	1	0.8234	SLC1A1/COL21A1/SLC38A2	3
KEGG	hsa04514	Cell adhesion molecules	6/968	149/8135	0.9998	1	0.8234	CD274/ICAM1/SDC4/PDCD1LG2/CADM1/GLG1	6
KEGG	hsa05150	Staphylococcus aureus infection	2/968	96/8135	0.9999	1	0.8234	ICAM1/KRT16	2
KEGG	hsa04080	Neuroactive ligand-receptor interaction	19/968	353/8135	1	1	0.8234	BDKRB2/BDKRB1/PTGER2/S1PR3/GHR/PTGFR/F2RL1/UCN/PARD3/CHRNB1/TAAR5/CCKAR/GRP/NR3C1/GRM2/AGTR2/THRA/HTR1D/GALR2	19
KEGG	hsa05322	Systemic lupus erythematosus	1/968	136/8135	1	1	0.8234	IFNG	1
KEGG	hsa04740	Olfactory transduction	2/968	440/8135	1	1	0.8234	RGS2/PRKACA	2