ONTOLOGY	ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	qvalue	geneID	Count
KEGG	hsa05169	Epstein-Barr virus infection	71/1069	202/8135	5.237e-16	1.723e-13	1.108e-13	CD247/CD3D/RUNX3/HLA-DRB4/HLA-DMA/MAPK13/GADD45A/TAP1/HLA-F/HLA-DMB/HLA-DOB/ITGAL/CDKN1A/GADD45B/IFNAR2/BLNK/PLCG2/CD40/MYD88/NFKBIE/BAK1/JUN/STAT1/HDAC1/OAS1/CCNA2/HES1/HLA-DPB1/TAPBP/CD3G/PSMC5/BTK/RELB/OAS2/HLA-DPA1/SYK/HLA-DOA/TNF/MAPK10/TRAF3/PSMC3/MYC/RAC1/NFKB1/DDB2/IKBKE/HLA-G/CXCL10/CD44/CD3E/HLA-A/LYN/EIF2AK2/ENTPD1/PIK3R1/USP7/HLA-DRA/GADD45G/PSMD8/BID/CDK4/CDK2/FAS/CD19/PIK3CA/TLR2/RB1/PDIA3/PSMC2/MAP2K6/FADD	71
KEGG	hsa05171	Coronavirus disease - COVID-19	70/1069	232/8135	4.443e-12	7.308e-10	4.7e-10	MMP3/AGTR1/C6/MAPK13/EGFR/PRKCB/C2/IFNAR2/PLCG2/MYD88/CFB/FAU/RPL34/JUN/STAT1/MMP1/RPS5/OAS1/RPL35/CFD/FCGR2A/MX2/OAS2/RPS25/RPL8/SYK/TNF/C3AR1/MAPK10/RPL13/TRAF3/RPL12/RPL18/RPS15/RPL14/RPL10A/RPL24/NFKB1/MAPK1/IKBKE/C1QB/CXCL10/RPL9/RPL31/RPS16/RPL27/EIF2AK2/RPS12/PIK3R1/RPLP0/RPS4Y1/RPL29/CASP1/RPS10/HBEGF/RPL30/RPL37/RPL11/RPS17/RPL38/RPL32/C7/PIK3CA/RPL19/TLR2/RPS28/MX1/RPL39/NLRP3/CYBB	70
KEGG	hsa04380	Osteoclast differentiation	45/1069	128/8135	1.324e-10	1.452e-08	9.337e-09	LILRB4/IL1R1/MAPK13/FOSL2/LCK/PPARG/IFNAR2/GRB2/BLNK/PLCG2/LCP2/FCGR3B/LILRA2/JUN/STAT1/FCGR3A/CYBA/LILRB2/FCGR2A/BTK/JUND/RELB/TNFSF11/SYK/FCGR2B/TYROBP/TNF/NCF2/MAPK10/SQSTM1/FOSB/RAC1/NFKB1/MAPK1/LILRA3/LILRB3/PIK3R1/CTSK/SOCS3/NCF4/PIK3CA/JUNB/IFNG/IFNGR2/MAP2K6	45
KEGG	hsa05140	Leishmaniasis	32/1069	77/8135	4.954e-10	4.075e-08	2.621e-08	HLA-DRB4/HLA-DMA/MAPK13/PTPN6/HLA-DMB/HLA-DOB/PRKCB/ITGB2/MYD88/FCGR3B/JUN/STAT1/FCGR3A/CYBA/HLA-DPB1/FCGR2A/EEF1A2/HLA-DPA1/HLA-DOA/ITGA4/TNF/NCF2/IL10/NFKB1/MAPK1/ITGAM/HLA-DRA/NCF4/TLR2/IFNG/IFNGR2/CYBB	32
KEGG	hsa05330	Allograft rejection	20/1069	38/8135	6.398e-09	4.21e-07	2.707e-07	HLA-DRB4/HLA-DMA/HLA-F/HLA-DMB/HLA-DOB/GZMB/CD40/HLA-DPB1/CD86/HLA-DPA1/HLA-DOA/TNF/IL10/HLA-G/HLA-A/HLA-DRA/PRF1/CD28/FAS/IFNG	20
KEGG	hsa05166	Human T-cell leukemia virus 1 infection	60/1069	222/8135	1.72e-08	9.43e-07	6.065e-07	CD3D/PTTG1/IL1R1/HLA-DRB4/HLA-DMA/LCK/IL2RG/IL2RB/ATF4/HLA-F/HLA-DMB/HLA-DOB/ITGAL/CDKN1A/ITGB2/CD40/CD4/CREB3L2/JUN/KAT5/CCNA2/HLA-DPB1/ADCY7/CD3G/RELB/ZFP36/HLA-DPA1/MSX2/HLA-DOA/EGR1/TNF/MAPK10/CCNB2/MYC/KAT2A/NFKB1/MAPK1/SMAD3/IL15/HLA-G/FDPS/IL15RA/TLN2/CD3E/HLA-A/GPS2/ADCY6/PIK3R1/CDKN2C/HLA-DRA/SLC25A6/CDK4/CDK2/MMP7/MAD2L1/NRAS/PIK3CA/TRRAP/RB1/BUB1B	60
KEGG	hsa04658	Th1 and Th2 cell differentiation	33/1069	92/8135	2.225e-08	1.046e-06	6.725e-07	CD247/CD3D/RUNX3/HLA-DRB4/HLA-DMA/MAPK13/LCK/IL2RG/IL2RB/HLA-DMB/HLA-DOB/CD4/NFKBIE/JUN/STAT1/HLA-DPB1/CD3G/HLA-DPA1/HLA-DOA/LAT/MAPK10/JAG1/NFKB1/MAPK1/STAT4/IL4R/CD3E/GATA3/ZAP70/HLA-DRA/MAF/IFNG/IFNGR2	33
KEGG	hsa05416	Viral myocarditis	25/1069	60/8135	3.714e-08	1.527e-06	9.821e-07	RAC2/HLA-DRB4/HLA-DMA/HLA-F/HLA-DMB/HLA-DOB/ITGAL/ITGB2/LAMA2/CD40/HLA-DPB1/CD86/HLA-DPA1/HLA-DOA/EIF4G1/RAC1/HLA-G/HLA-A/CD55/HLA-DRA/ABL2/PRF1/MYH7/BID/CD28	25
KEGG	hsa04940	Type I diabetes mellitus	20/1069	43/8135	9.522e-08	3.481e-06	2.238e-06	HLA-DRB4/HLA-DMA/HLA-F/HLA-DMB/HLA-DOB/GZMB/HLA-DPB1/CPE/CD86/HLA-DPA1/HLA-DOA/TNF/PTPRN2/HLA-G/HLA-A/HLA-DRA/PRF1/CD28/FAS/IFNG	20
KEGG	hsa05323	Rheumatoid arthritis	32/1069	93/8135	1.123e-07	3.694e-06	2.376e-06	CCL5/MMP3/HLA-DRB4/HLA-DMA/HLA-DMB/HLA-DOB/ITGAL/ITGB2/JUN/MMP1/HLA-DPB1/CD86/CTSL/TNFSF11/HLA-DPA1/CXCL6/HLA-DOA/TNF/LTB/IL15/CXCL1/TCIRG1/IL18/CTSK/HLA-DRA/CXCL12/CD28/TLR2/IFNG/CCL20/ATP6V1A/ANGPT1	32
KEGG	hsa04660	T cell receptor signaling pathway	34/1069	104/8135	1.869e-07	5.59e-06	3.595e-06	CD247/CD3D/MAPK13/LCK/PTPN6/CBLB/CD8A/VAV1/GRB2/CD4/LCP2/NFKBIE/PAK1/RASGRP1/ITK/JUN/PTPRC/CD3G/LAT/TNF/MAPK10/IL10/NFKB1/MAPK1/CD3E/PIK3R1/ZAP70/ICOS/CDK4/CD28/PAK2/NRAS/PIK3CA/IFNG	34
KEGG	hsa04666	Fc gamma R-mediated phagocytosis	32/1069	97/8135	3.389e-07	9.29e-06	5.975e-06	GSN/RAC2/INPP5D/WASF3/VAV1/PRKCB/PLCG2/BIN1/PAK1/FCGR3B/ARPC1B/ARPC2/MARCKS/FCGR3A/AMPH/HCK/PTPRC/FCGR2A/SYK/FCGR2B/LAT/ARPC3/ARPC5/VASP/RAC1/MAPK1/LYN/PIK3R1/MYO10/ARF6/PIK3CA/ACTR3	32
KEGG	hsa04064	NF-kappa B signaling pathway	33/1069	104/8135	6.155e-07	1.558e-05	1.002e-05	IL1R1/LCK/GADD45A/GADD45B/PRKCB/BLNK/PLCG2/CD40/MYD88/PARP1/CCL13/BTK/CD14/RELB/TNFSF11/SYK/LAT/TRAF1/TNF/LTB/TRAF3/NFKB1/CCL19/CXCL1/LYN/BIRC3/CSNK2A2/ZAP70/GADD45G/CXCL12/LY96/CARD10/BCL2A1	33
KEGG	hsa04662	B cell receptor signaling pathway	28/1069	82/8135	8.303e-07	1.951e-05	1.255e-05	RAC2/LILRB4/PTPN6/INPP5D/VAV1/PRKCB/GRB2/BLNK/PLCG2/NFKBIE/LILRA2/JUN/CD79A/LILRB2/BTK/SYK/FCGR2B/RAC1/NFKB1/MAPK1/LILRA3/LILRB3/LYN/PIK3R1/CD19/CD79B/NRAS/PIK3CA	28
KEGG	hsa04650	Natural killer cell mediated cytotoxicity	38/1069	131/8135	1.127e-06	2.473e-05	1.59e-05	CD247/RAC2/LCK/PTPN6/CD48/ITGAL/VAV1/PRKCB/ITGB2/IFNAR2/GZMB/GRB2/PLCG2/LCP2/PAK1/FCGR3B/FCGR3A/MICB/SYK/LAT/TYROBP/TNF/TNFSF10/FCER1G/RAC1/MAPK1/HLA-G/HLA-A/SH2D1A/PIK3R1/ZAP70/PRF1/BID/FAS/NRAS/PIK3CA/IFNG/IFNGR2	38
KEGG	hsa04672	Intestinal immune network for IgA production	20/1069	49/8135	1.281e-06	2.635e-05	1.695e-05	HLA-DRB4/HLA-DMA/HLA-DMB/ITGB7/HLA-DOB/CD40/TNFRSF17/HLA-DPB1/CD86/HLA-DPA1/CXCR4/HLA-DOA/ITGA4/IL10/IL15/IL15RA/HLA-DRA/CXCL12/ICOS/CD28	20
KEGG	hsa04659	Th17 cell differentiation	33/1069	108/8135	1.601e-06	3.068e-05	1.973e-05	CD247/CD3D/IL1R1/HLA-DRB4/HLA-DMA/MAPK13/LCK/IL2RG/IL2RB/HLA-DMB/HLA-DOB/CD4/NFKBIE/JUN/STAT1/HLA-DPB1/CD3G/HLA-DPA1/HLA-DOA/LAT/MAPK10/IL27RA/NFKB1/MAPK1/SMAD3/IL4R/CD3E/GATA3/ZAP70/HLA-DRA/HSP90AB1/IFNG/IFNGR2	33
KEGG	hsa05340	Primary immunodeficiency	17/1069	38/8135	1.743e-06	3.068e-05	1.973e-05	CD3D/LCK/IL2RG/TAP1/CD8A/BLNK/CD40/IL7R/RFX5/CD4/CD79A/PTPRC/BTK/CD3E/ZAP70/ICOS/CD19	17
KEGG	hsa04640	Hematopoietic cell lineage	31/1069	99/8135	1.848e-06	3.068e-05	1.973e-05	CD3D/IL1R1/HLA-DRB4/HLA-DMA/CD37/HLA-DMB/CD8A/HLA-DOB/CD2/IL7R/CD4/CSF2RA/HLA-DPB1/CD3G/CD14/HLA-DPA1/HLA-DOA/ITGA4/TNF/CD34/CD38/ITGAM/CD44/IL4R/CD3E/CD33/CD55/HLA-DRA/TFRC/CD19/MS4A1	31
KEGG	hsa05332	Graft-versus-host disease	18/1069	42/8135	1.865e-06	3.068e-05	1.973e-05	HLA-DRB4/HLA-DMA/HLA-F/HLA-DMB/HLA-DOB/GZMB/HLA-DPB1/CD86/HLA-DPA1/HLA-DOA/TNF/HLA-G/HLA-A/HLA-DRA/PRF1/CD28/FAS/IFNG	18
KEGG	hsa04612	Antigen processing and presentation	26/1069	78/8135	3.414e-06	5.349e-05	3.44e-05	HLA-DRB4/HLA-DMA/TAP1/HLA-F/HLA-DMB/CD8A/HLA-DOB/RFX5/CD4/HSPA6/HLA-DPB1/TAPBP/CTSL/HLA-DPA1/CTSS/HLA-DOA/TNF/CD74/PSME1/HLA-G/HLA-A/HLA-DRA/HSP90AB1/HSPA5/PDIA3/IFNG	26
KEGG	hsa05321	Inflammatory bowel disease	23/1069	65/8135	3.958e-06	5.918e-05	3.806e-05	HLA-DRB4/HLA-DMA/IL2RG/HLA-DMB/HLA-DOB/JUN/STAT1/HLA-DPB1/HLA-DPA1/HLA-DOA/TNF/IL10/NFKB1/STAT4/SMAD3/IL4R/GATA3/IL18/HLA-DRA/TLR2/MAF/IFNG/IFNGR2	23
KEGG	hsa04514	Cell adhesion molecules	40/1069	149/8135	5.064e-06	7.243e-05	4.658e-05	HLA-DRB4/SDC1/HLA-DMA/HLA-F/HLA-DMB/SELL/ICAM3/ITGB7/CD8A/HLA-DOB/ITGAL/CD2/ITGB2/SELPLG/SDC4/CD40/CLDN5/CD4/HLA-DPB1/PTPRC/CD86/HLA-DPA1/HLA-DOA/ITGA4/CLDN7/CD34/HLA-G/ITGAM/GLG1/HLA-A/SDC3/CD226/NLGN1/HLA-DRA/ICOS/CADM1/CD28/PTPRF/JAM3/CD6	40
KEGG	hsa04210	Apoptosis	37/1069	136/8135	8.166e-06	0.0001119	7.199e-05	GADD45A/ATF4/CTSH/GADD45B/GZMB/DDIT3/BAK1/JUN/CSF2RB/PARP1/CTSL/CTSC/CTSS/TRAF1/TNF/MAPK10/TNFSF10/NFKB1/MAPK1/PARP4/CTSW/CTSZ/PTPN13/BIRC3/PIK3R1/CTSK/DAXX/GADD45G/PRF1/LMNB1/BID/FAS/DFFA/NRAS/PIK3CA/BCL2A1/FADD	37
KEGG	hsa05135	Yersinia infection	37/1069	137/8135	9.803e-06	0.000129	8.296e-05	RAC2/MAPK13/LCK/RPS6KA1/CD8A/VAV1/MYD88/CD4/LCP2/ARPC1B/JUN/ARPC2/BAIAP2/FCGR2A/LAT/ITGA4/TNF/MAPK10/ARPC3/RHOG/ARPC5/IL10/RAC1/NFKB1/MAPK1/RPS6KA2/PIK3R1/IL18/ZAP70/CASP1/ARF6/PIK3CA/ACTR3/MAP2K6/SKAP2/NLRP3/ARHGEF7	37
KEGG	hsa05145	Toxoplasmosis	32/1069	112/8135	1.109e-05	0.0001354	8.71e-05	HLA-DRB4/HLA-DMA/MAPK13/HLA-DMB/HLA-DOB/LAMA2/IL10RA/CD40/MYD88/HSPA6/ALOX5/STAT1/LAMA3/HLA-DPB1/LDLR/HLA-DPA1/CCR5/HLA-DOA/TNF/MAPK10/IL10/NFKB1/MAPK1/BIRC3/LAMB2/HLA-DRA/LY96/TLR2/IFNG/IFNGR2/MAP2K6/PPIF	32
KEGG	hsa05130	Pathogenic Escherichia coli infection	48/1069	197/8135	1.111e-05	0.0001354	8.71e-05	IL1R1/MAPK13/PTPN6/WASF3/NCKAP1L/MYO1F/CLDN5/MYD88/PAK1/CYFIP2/ARPC1B/BAK1/JUN/ARPC2/BAIAP2/FCGR2A/MYH11/MYO1C/CYTH1/CYFIP1/TNF/MAPK10/CLDN7/HCLS1/SEC24D/ARPC3/NCL/CASP4/ARPC5/TNFSF10/RAC1/NFKB1/MAPK1/TUBB/IL18/CTTN/MYO10/CASP1/NCKAP1/ARF6/TMED10/FAS/PAK2/ACTR3/ABCF2/F2R/NLRP3/FADD	48
KEGG	hsa04062	Chemokine signaling pathway	47/1069	192/8135	1.201e-05	0.0001411	9.076e-05	CCL5/RAC2/CCL18/FOXO3/CX3CL1/VAV1/PRKCB/CXCL13/GRB2/PLCG2/PAK1/ITK/STAT1/CXCL9/CCR7/HCK/GRK5/ARRB2/ADCY7/CCL13/CXCL6/CXCR4/PLCB2/CCR5/PLCB1/CCR2/RAC1/NFKB1/MAPK1/DOCK2/CCL19/CXCL10/PARD3/CXCL1/LYN/ADCY6/PIK3R1/CXCR6/CCR1/CXCL12/GNG11/CX3CR1/NRAS/PIK3CA/CCL20/GNG5/CCR6	47
KEGG	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	27/1069	89/8135	1.623e-05	0.0001841	0.0001184	CD247/CD3D/MAPK13/EGFR/LCK/PTPN6/MYD88/CD4/NFKBIE/RASGRP1/JUN/STAT1/CD3G/LAT/NFKB1/MAPK1/CD3E/PIK3R1/CSNK2A2/ZAP70/CD28/NRAS/PIK3CA/TLR2/IFNG/IFNGR2/MAP2K6	27
KEGG	hsa05320	Autoimmune thyroid disease	19/1069	53/8135	2.199e-05	0.0002411	0.0001551	HLA-DRB4/HLA-DMA/HLA-F/HLA-DMB/HLA-DOB/GZMB/CD40/HLA-DPB1/CD86/HLA-DPA1/HLA-DOA/IL10/HLA-G/HLA-A/TPO/HLA-DRA/PRF1/CD28/FAS	19
KEGG	hsa04668	TNF signaling pathway	31/1069	112/8135	3.02e-05	0.0003163	0.0002034	CCL5/MMP3/MAPK13/ATF4/CX3CL1/CREB3L2/JUN/CXCL6/TRAF1/TNF/MAPK10/TRAF3/TNFRSF1B/JAG1/NFKB1/MAPK1/IL15/CXCL10/CXCL1/VEGFC/BIRC3/PIK3R1/SOCS3/FAS/PIK3CA/JUNB/CEBPB/CCL20/MAP2K6/FADD/MMP9	31
KEGG	hsa05202	Transcriptional misregulation in cancer	46/1069	193/8135	3.076e-05	0.0003163	0.0002034	ZBTB16/MMP3/FOXO1/GADD45A/IL2RB/ITGB7/CDKN1A/GADD45B/PPARG/GZMB/DDIT3/NUPR1/CD40/BAK1/HDAC1/CCNA2/CD14/BMP2K/CD86/HOXA10/HHEX/TRAF1/PAX8/LYL1/CCNT1/MYC/NFKB1/PLAT/DDB2/MLF1/ITGAM/BIRC3/CDKN2C/GADD45G/SIX1/ELANE/AFF1/RUNX1T1/PER2/EWSR1/MAF/FLI1/CEBPB/CDK9/BCL2A1/MMP9	46
KEGG	hsa05152	Tuberculosis	43/1069	180/8135	5.228e-05	0.0005213	0.0003352	CORO1A/HLA-DRB4/HLA-DMA/MAPK13/HLA-DMB/HLA-DOB/VDR/ITGB2/IL10RA/ITGAX/RFX5/MYD88/FCGR3B/STAT1/FCGR3A/HLA-DPB1/FCGR2A/CD14/HLA-DPA1/SYK/FCGR2B/CTSS/HLA-DOA/TNF/MAPK10/CD74/IL10/CALM1/FCER1G/NFKB1/MAPK1/ITGAM/TCIRG1/IL18/PLK3/HLA-DRA/BID/LAMP2/TLR2/CEBPB/IFNG/IFNGR2/FADD	43
KEGG	hsa04061	Viral protein interaction with cytokine and cytokine receptor	28/1069	100/8135	5.778e-05	0.0005417	0.0003484	CCL5/CCL18/IL2RG/IL2RB/CX3CL1/CXCL13/IL10RA/CXCL9/CCR7/CCL13/CXCL6/CXCR4/CCR5/TNF/CCR2/TNFRSF1B/IL10/TNFSF10/CCL19/CXCL10/CXCL1/IL18/CCR1/CXCL12/CX3CR1/ACKR3/CCL20/CCR6	28
KEGG	hsa04933	AGE-RAGE signaling pathway in diabetic complications	28/1069	100/8135	5.778e-05	0.0005417	0.0003484	AGTR1/MAPK13/COL1A1/FOXO1/COL3A1/COL1A2/PRKCB/PLCG2/JUN/STAT1/PLCB2/PLCB1/EGR1/TNF/MAPK10/RAC1/NFKB1/MAPK1/PIM1/SMAD3/VEGFC/PIK3R1/CDK4/NRAS/PIK3CA/VEGFB/AGT/CYBB	28
KEGG	hsa05417	Lipid and atherosclerosis	49/1069	215/8135	5.928e-05	0.0005417	0.0003484	CCL5/MMP3/MAPK13/ATF4/VAV1/PPARG/DDIT3/CD40/MYD88/HSPA6/JUN/MMP1/CYBA/XBP1/CD14/LDLR/PLCB2/PLCB1/TNF/NCF2/MAPK10/TRAF3/CALM1/TNFSF10/ABCG1/RAC1/NFKB1/MAPK1/IKBKE/CXCL1/LYN/PIK3R1/IL18/POU2F1/CASP1/VLDLR/HSP90AB1/BID/NCF4/LY96/HSPA5/FAS/NRAS/PIK3CA/TLR2/MAP2K6/NLRP3/MMP9/CYBB	49
KEGG	hsa04142	Lysosome	34/1069	132/8135	6.416e-05	0.0005705	0.0003669	CTSH/MAN2B1/NAGA/PPT1/TPP1/AP1G2/PLA2G15/LITAF/CTSL/CTSC/CTSS/ACP2/GNS/GALC/LAMP3/NPC1/LAPTM5/CTSW/CTSZ/CLTCL1/SCARB2/ARSA/TCIRG1/GLA/DNASE2/CTSK/CLTB/ARSB/NAGPA/LAMP2/HEXA/LIPA/IGF2R/AGA	34
KEGG	hsa05310	Asthma	13/1069	31/8135	6.745e-05	0.000584	0.0003756	HLA-DRB4/HLA-DMA/HLA-DMB/HLA-DOB/CD40/HLA-DPB1/HLA-DPA1/HLA-DOA/TNF/IL10/FCER1G/HLA-DRA/PRG2	13
KEGG	hsa05164	Influenza A	41/1069	171/8135	7.103e-05	0.0005992	0.0003854	CCL5/HLA-DRB4/HLA-DMA/HLA-DMB/HLA-DOB/PRKCB/IFNAR2/MYD88/BAK1/STAT1/OAS1/HLA-DPB1/DNAJB1/MX2/OAS2/HLA-DPA1/HLA-DOA/TNF/TRAF3/TNFSF10/NFKB1/MAPK1/IKBKE/CXCL10/FDPS/EIF2AK2/PIK3R1/IL18/CASP1/HLA-DRA/BID/SLC25A6/SOCS3/CDK4/FAS/PIK3CA/IFNG/IFNGR2/MX1/NLRP3/FADD	41
KEGG	hsa05167	Kaposi sarcoma-associated herpesvirus infection	45/1069	194/8135	7.546e-05	0.0006207	0.0003991	MAPK13/TCF7L2/HLA-F/CDKN1A/IFNAR2/PLCG2/TCF7/BAK1/JUN/STAT1/HCK/MICB/ZFP36/CD86/SYK/CCR5/MAPK10/TRAF3/CALM1/MYC/RAC1/NFKB1/MAPK1/IKBKE/HLA-G/HLA-A/CXCL1/LYN/EIF2AK2/RCAN1/PIK3R1/CCR1/GNG11/BID/CDK4/FAS/UBC/NRAS/PIK3CA/RB1/MAP1LC3B/MAP2K6/GNG5/FADD/LEF1	45
KEGG	hsa04664	Fc epsilon RI signaling pathway	21/1069	68/8135	0.0001046	0.0008224	0.0005289	RAC2/MAPK13/INPP5D/VAV1/GRB2/PLCG2/LCP2/ALOX5/BTK/SYK/LAT/TNF/MAPK10/FCER1G/RAC1/MAPK1/LYN/PIK3R1/NRAS/PIK3CA/MAP2K6	21
KEGG	hsa05132	Salmonella infection	54/1069	249/8135	0.000105	0.0008224	0.0005289	MAPK13/RHOB/TCF7L2/WASF3/RHOH/MYL9/NCKAP1L/TCF7/MYD88/PAK1/CYFIP2/ARPC1B/BAK1/JUN/ARPC2/PTPRC/CD14/CYTH1/CYFIP1/TNF/MAPK10/ARPC3/ANXA2/CASP4/RHOG/ARPC5/MYC/TNFSF10/RAC1/NFKB1/MAPK1/MYL2/DCTN3/BIRC3/KLC1/PFN1/TUBB/IL18/CASP1/NCKAP1/HSP90AB1/ARF6/LY96/RALA/PLEKHM1/PIK3CA/ACTR3/TLR2/KIF5C/MAP2K6/NLRP3/FADD/LEF1/S100A10	54
KEGG	hsa04670	Leukocyte transendothelial migration	30/1069	114/8135	0.000112	0.0008457	0.0005439	RAC2/MAPK13/RHOH/MYL9/ITGAL/VAV1/PRKCB/ITGB2/PLCG2/CLDN5/ITK/THY1/RAPGEF3/CYBA/CXCR4/ITGA4/NCF2/CLDN7/ACTN4/VASP/RAC1/ITGAM/MYL2/PIK3R1/CXCL12/NCF4/PIK3CA/JAM3/MMP9/CYBB	30
KEGG	hsa04145	Phagosome	37/1069	152/8135	0.0001131	0.0008457	0.0005439	CORO1A/HLA-DRB4/HLA-DMA/TAP1/HLA-F/HLA-DMB/HLA-DOB/ITGB2/FCGR3B/FCGR3A/CYBA/HLA-DPB1/FCGR2A/CD14/CTSL/HLA-DPA1/FCGR2B/CTSS/HLA-DOA/HGS/NCF2/RAC1/THBS2/HLA-G/ITGAM/HLA-A/TCIRG1/THBS3/TUBB/HLA-DRA/MSR1/TFRC/LAMP2/NCF4/TLR2/ATP6V1A/CYBB	37
KEGG	hsa05216	Thyroid cancer	14/1069	37/8135	0.0001355	0.0009905	0.000637	GADD45A/TCF7L2/CDKN1A/GADD45B/PPARG/TCF7/BAK1/PAX8/MYC/MAPK1/DDB2/GADD45G/NRAS/LEF1	14
KEGG	hsa04910	Insulin signaling pathway	34/1069	137/8135	0.0001418	0.001014	0.0006522	FASN/PCK1/FOXO1/SREBF1/SOCS2/LIPE/CBLB/HK3/EIF4E2/GRB2/PDE3B/IRS1/PPP1R3C/TRIP10/MAPK10/SLC2A4/CALM1/MAPK1/ACACB/PPP1CA/MKNK1/PRKAR2B/PIK3R1/SORBS1/PHKA1/SOCS3/EIF4EBP1/PTPRF/ACACA/NRAS/PHKG1/PIK3CA/RAPGEF1/PPP1CC	34
KEGG	hsa05150	Staphylococcus aureus infection	26/1069	96/8135	0.0001908	0.001335	0.0008588	HLA-DRB4/HLA-DMA/PTAFR/HLA-DMB/HLA-DOB/ITGAL/C2/ITGB2/SELPLG/CFB/FCGR3B/CFH/FCGR3A/HLA-DPB1/CFD/FCGR2A/HLA-DPA1/FCGR2B/HLA-DOA/C3AR1/IL10/FPR3/C1QB/ITGAM/HLA-DRA/FPR1	26
KEGG	hsa05221	Acute myeloid leukemia	20/1069	67/8135	0.0002537	0.001739	0.001118	ZBTB16/TCF7L2/GRB2/TCF7/PIM2/CCNA2/CD14/MYC/NFKB1/MAPK1/PIM1/ITGAM/PIK3R1/EIF4EBP1/NRAS/RUNX1T1/PER2/PIK3CA/BCL2A1/LEF1	20
KEGG	hsa04936	Alcoholic liver disease	34/1069	142/8135	0.0002954	0.001975	0.00127	FASN/ADH1A/ADH1B/SCD/ADH1C/ADIPOQ/MAPK13/FOXO1/ADIPOR2/SREBF1/TCF7L2/FOXO3/C2/TCF7/MYD88/LPIN1/CD14/TNF/C3AR1/MAPK10/TRAF3/NFKB1/ACACB/IKBKE/C1QB/ACADVL/CXCL1/ADH5/LY96/FAS/ACACA/MAP2K6/FADD/LEF1	34
KEGG	hsa04068	FoxO signaling pathway	32/1069	131/8135	0.0003002	0.001975	0.00127	PCK1/GABARAPL1/MAPK13/EGFR/CCNB1/FOXO1/GADD45A/FOXO3/CDKN1A/GADD45B/GRB2/IL7R/IRS1/MAPK10/CCNB2/SLC2A4/IL10/TNFSF10/MAPK1/SMAD3/PLK1/PIK3R1/FOXO4/USP7/PLK3/GADD45G/HOMER3/CDK2/NRAS/PIK3CA/STK11/CCNG2	32
KEGG	hsa05170	Human immunodeficiency virus 1 infection	46/1069	212/8135	0.0003306	0.002133	0.001371	CD247/CD3D/RAC2/MAPK13/CCNB1/TAP1/HLA-F/PRKCB/PLCG2/MYD88/CD4/PAK1/BAK1/JUN/APOBEC3G/APOBEC3C/AP1G2/TAPBP/CD3G/CXCR4/CCR5/TNF/MAPK10/CCNB2/TNFRSF1B/CALM1/RAC1/NFKB1/MAPK1/HLA-G/CD3E/HLA-A/WEE1/PIK3R1/GNG11/BID/FAS/PAK2/NRAS/PIK3CA/TLR2/SAMHD1/PDIA3/MAP2K6/GNG5/FADD	46
KEGG	hsa04657	IL-17 signaling pathway	25/1069	94/8135	0.0003416	0.002161	0.00139	MMP3/MAPK13/JUN/MMP1/TRAF3IP2/S100A9/JUND/CXCL6/TNF/MAPK10/TRAF3/S100A8/FOSB/NFKB1/MAPK1/IKBKE/CXCL10/CXCL1/MAPK7/HSP90AB1/CEBPB/IFNG/CCL20/FADD/MMP9	25
KEGG	hsa00350	Tyrosine metabolism	13/1069	36/8135	0.0004011	0.00249	0.001601	MAOA/ADH1A/ADH1B/ADH1C/AOC3/PNMT/FAH/AOX1/COMT/AOC2/TPO/ADH5/HPD	13
KEGG	hsa05162	Measles	33/1069	139/8135	0.0004251	0.002543	0.001635	CD3D/IL2RG/IL2RB/CBLB/SLAMF1/IFNAR2/MYD88/HSPA6/BAK1/JUN/STAT1/OAS1/CD3G/MX2/OAS2/FCGR2B/MAPK10/TRAF3/NFKB1/IKBKE/CD3E/EIF2AK2/PIK3R1/CSNK2A2/BID/CDK4/CD28/CDK2/FAS/PIK3CA/TLR2/MX1/FADD	33
KEGG	hsa05418	Fluid shear stress and atherosclerosis	33/1069	139/8135	0.0004251	0.002543	0.001635	RAC2/IL1R1/SDC1/MAPK13/NQO1/SDC4/ASS1/JUN/CYBA/CTSL/TNF/NCF2/MAPK10/BMP4/SQSTM1/CALM1/RAC1/NFKB1/PLAT/DUSP1/HMOX1/PIK3R1/MAPK7/HSP90AB1/GPC1/CAV2/PIK3CA/ACVR2B/GSTM3/IFNG/MAP2K6/GSTO1/MMP9	33
KEGG	hsa05210	Colorectal cancer	23/1069	86/8135	0.000534	0.003137	0.002017	RAC2/EGFR/GADD45A/TGFA/TCF7L2/CDKN1A/GADD45B/GRB2/TCF7/BAK1/JUN/MAPK10/MYC/RAC1/MAPK1/DDB2/SMAD3/PIK3R1/GADD45G/RALA/NRAS/PIK3CA/LEF1	23
KEGG	hsa00920	Sulfur metabolism	6/1069	10/8135	0.0006652	0.00384	0.002469	ETHE1/PAPSS2/MPST/SELENBP1/PAPSS1/TST	6
KEGG	hsa04152	AMPK signaling pathway	29/1069	120/8135	0.0006828	0.003873	0.002491	FASN/SCD/PCK1/ADIPOQ/FOXO1/ADIPOR2/SREBF1/LIPE/FOXO3/PPARG/CREB3L2/IRS1/CCNA2/EEF2/RAB8A/PFKFB1/SLC2A4/ACACB/PFKM/TBC1D1/PIK3R1/EIF4EBP1/HNF4A/ACACA/PIK3CA/ULK1/STK11/PPP2R5C/PFKFB3	29
KEGG	hsa05163	Human cytomegalovirus infection	47/1069	225/8135	0.0006998	0.003902	0.00251	CCL5/RAC2/IL1R1/MAPK13/EGFR/TAP1/ATF4/HLA-F/CX3CL1/CDKN1A/PRKCB/GRB2/IL10RA/CREB3L2/BAK1/PTGER3/ADCY7/TAPBP/CXCR4/PLCB2/CCR5/PLCB1/TNF/CALM1/MYC/RAC1/NFKB1/MAPK1/HLA-G/HLA-A/ADCY6/PIK3R1/CCR1/CXCL12/GNG11/BID/CDK4/EIF4EBP1/FAS/NRAS/PIK3CA/RB1/PDIA3/MAP2K6/GNG5/FADD/PTGER4	47
KEGG	hsa04620	Toll-like receptor signaling pathway	26/1069	104/8135	0.0007384	0.004049	0.002604	CCL5/MAPK13/SPP1/IFNAR2/CD40/MYD88/JUN/STAT1/CXCL9/CD14/CD86/TNF/MAPK10/TRAF3/RAC1/NFKB1/MAPK1/IKBKE/CXCL10/PIK3R1/CTSK/LY96/PIK3CA/TLR2/MAP2K6/FADD	26
KEGG	hsa05415	Diabetic cardiomyopathy	43/1069	203/8135	0.0008637	0.004602	0.002959	RAC2/AGTR1/MAPK13/COL1A1/COL3A1/COL1A2/PRKCB/COX7A1/CYBA/IRS1/PARP1/PLCB2/PLCB1/NCF2/MAPK10/PLN/SLC2A4/NDUFV1/NDUFS7/RAC1/NFKB1/NDUFB7/SMAD3/NDUFS5/PPP1CA/PIK3R1/SLC25A6/NCF4/NDUFC1/PIK3CA/AGT/UQCRFS1/NDUFB5/PDK4/PPIF/NDUFS6/NDUFAB1/PPP1CC/COX6A2/MMP9/PDHA1/PDK2/CYBB	43
KEGG	hsa04218	Cellular senescence	35/1069	156/8135	0.0008789	0.004602	0.002959	MAPK13/CCNB1/FOXO1/GADD45A/HLA-F/FOXO3/CDKN1A/ZFP36L2/GADD45B/CCNA2/TRAF3IP2/CCNB2/SQSTM1/CALM1/MYC/NFKB1/MAPK1/SMAD3/HLA-G/PPP1CA/HLA-A/FOXM1/PIK3R1/GADD45G/SLC25A6/CDK4/EIF4EBP1/CDK2/NRAS/PIK3CA/E2F5/RB1/LIN37/MAP2K6/PPP1CC	35
KEGG	hsa04060	Cytokine-cytokine receptor interaction	58/1069	295/8135	0.0008812	0.004602	0.002959	CCL5/CD27/IL1R1/CCL18/IL32/IL2RG/IL2RB/CX3CL1/IFNAR2/CXCL13/IL10RA/CD40/IL7R/CD4/CXCL9/CSF2RB/CCR7/TNFRSF17/CSF2RA/TNFSF9/CCL13/TNFSF11/CXCL6/CXCR4/CCR5/TNF/LTB/BMP4/IL27RA/CCR2/TNFRSF1B/IL1RN/INHBB/IL10/TNFSF10/GDF15/CCL19/IL15/CXCL10/IL15RA/IL4R/BMP5/CXCL1/LIFR/IL18/CXCR6/CCR1/CXCL12/CX3CR1/FAS/ACVR2B/ACKR3/TNFSF8/IFNG/CCL20/IFNGR2/CCR6/CD70	58
KEGG	hsa05213	Endometrial cancer	17/1069	58/8135	0.0009111	0.004683	0.003012	EGFR/GADD45A/TCF7L2/FOXO3/CDKN1A/GADD45B/GRB2/TCF7/BAK1/MYC/MAPK1/DDB2/PIK3R1/GADD45G/NRAS/PIK3CA/LEF1	17
KEGG	hsa04611	Platelet activation	29/1069	124/8135	0.001193	0.006041	0.003885	MAPK13/COL1A1/COL3A1/COL1A2/PLCG2/LCP2/VAMP8/RASGRP1/ADCY7/FCGR2A/BTK/SYK/PLCB2/PLCB1/VASP/MYLK/FCER1G/MAPK1/PPP1CA/TLN2/LYN/ADCY6/PIK3R1/STIM1/PIK3CA/PRKG1/SNAP23/F2R/PPP1CC	29
KEGG	hsa05142	Chagas disease	25/1069	102/8135	0.001258	0.006175	0.003971	CD247/CD3D/CCL5/MAPK13/GNA15/MYD88/JUN/CD3G/PLCB2/PLCB1/TNF/MAPK10/IL10/NFKB1/MAPK1/C1QB/CD3E/PIK3R1/FAS/PIK3CA/TLR2/BDKRB2/IFNG/IFNGR2/FADD	25
KEGG	hsa05146	Amoebiasis	25/1069	102/8135	0.001258	0.006175	0.003971	IL1R1/HSPB1/COL1A1/COL3A1/COL1A2/GNA15/PRKCB/ITGB2/LAMA2/LAMA3/CD14/PLCB2/PLCB1/TNF/ACTN4/IL10/NFKB1/ITGAM/CXCL1/PIK3R1/LAMB2/PRDX1/PIK3CA/TLR2/IFNG	25
KEGG	hsa05144	Malaria	15/1069	50/8135	0.001384	0.006696	0.004306	SDC1/ITGAL/ITGB2/CD40/MYD88/ACKR1/KLRB1/TNF/IL10/THBS2/GYPC/THBS3/IL18/TLR2/IFNG	15
KEGG	hsa05133	Pertussis	20/1069	76/8135	0.001494	0.007023	0.004517	MAPK13/C2/ITGB2/IRF8/MYD88/JUN/CD14/CXCL6/TNF/MAPK10/IL10/CALM1/NFKB1/MAPK1/C1QB/ITGAM/CASP1/LY96/SERPING1/NLRP3	20
KEGG	hsa05212	Pancreatic cancer	20/1069	76/8135	0.001494	0.007023	0.004517	RAC2/EGFR/GADD45A/TGFA/CDKN1A/GADD45B/BAK1/STAT1/MAPK10/RAC1/NFKB1/MAPK1/DDB2/SMAD3/PIK3R1/GADD45G/CDK4/RALA/PIK3CA/RB1	20
KEGG	hsa04110	Cell cycle	29/1069	126/8135	0.001555	0.007206	0.004634	PTTG1/CCNB1/GADD45A/CDKN1A/GADD45B/PCNA/HDAC1/CCNA2/CCNB2/MCM5/MYC/SMAD3/MCM6/PLK1/WEE1/YWHAB/CDKN2C/GADD45G/CDK4/CDC25B/CDK2/CDC6/MAD2L1/E2F5/RB1/PKMYT1/DBF4/TFDP1/BUB1B	29
KEGG	hsa04216	Ferroptosis	13/1069	41/8135	0.001628	0.00744	0.004784	TF/PCBP2/SLC39A14/GPX4/SLC39A8/ACSL1/HMOX1/TFRC/SLC3A2/PRNP/MAP1LC3B/GCLM/CYBB	13
KEGG	hsa05223	Non-small cell lung cancer	19/1069	72/8135	0.001875	0.008451	0.005435	EGFR/GADD45A/TGFA/FOXO3/CDKN1A/GADD45B/PRKCB/GRB2/PLCG2/BAK1/MAPK1/DDB2/PIK3R1/GADD45G/CDK4/NRAS/PIK3CA/RB1/KIF5C	19
KEGG	hsa04810	Regulation of actin cytoskeleton	44/1069	218/8135	0.002097	0.009321	0.005994	GSN/RAC2/EGFR/ITGB7/MYL9/ITGAL/VAV1/NCKAP1L/ITGB2/ITGAX/PAK1/CYFIP2/ARPC1B/ARPC2/BAIAP2/ITGA7/MYH11/CXCR4/ITGA4/CYFIP1/ARPC3/ARPC5/ACTN4/MYLK/RAC1/MAPK1/ITGAM/PPP1CA/MYL2/PFN1/PIK3R1/PPP1R12B/NCKAP1/CXCL12/PAK2/NRAS/PIK3CA/ACTR3/FGFR2/BDKRB2/DIAPH2/F2R/PPP1CC/ARHGEF7	44
KEGG	hsa00620	Pyruvate metabolism	14/1069	47/8135	0.002133	0.009358	0.006018	ADH1A/ADH1B/PCK1/ADH1C/AKR1A1/ME2/PC/ACACB/LDHB/ADH5/ACACA/ACAT2/GRHPR/PDHA1	14
KEGG	hsa04926	Relaxin signaling pathway	29/1069	129/8135	0.002273	0.009841	0.006329	MAPK13/EGFR/COL1A1/ATF4/COL3A1/COL1A2/GNA15/GRB2/CREB3L2/JUN/MMP1/ARRB2/ADCY7/EDNRB/PLCB2/PLCB1/MAPK10/NFKB1/MAPK1/VEGFC/ADCY6/PIK3R1/GNG11/NRAS/PIK3CA/VEGFB/GNG5/MMP9/ACTA2	29
KEGG	hsa05215	Prostate cancer	23/1069	97/8135	0.00306	0.01307	0.008407	MMP3/EGFR/FOXO1/TGFA/TCF7L2/ATF4/CDKN1A/GRB2/TCF7/CREB3L2/AR/NFKB1/MAPK1/PLAT/PIK3R1/HSP90AB1/CDK2/NRAS/PIK3CA/FGFR2/RB1/MMP9/LEF1	23
KEGG	hsa05214	Glioma	19/1069	75/8135	0.00311	0.01312	0.008436	EGFR/GADD45A/TGFA/CDKN1A/GADD45B/PRKCB/GRB2/PLCG2/BAK1/CALM1/MAPK1/CAMK1/DDB2/PIK3R1/GADD45G/CDK4/NRAS/PIK3CA/RB1	19
KEGG	hsa05205	Proteoglycans in cancer	41/1069	205/8135	0.003473	0.01446	0.009301	SDC1/MAPK13/EGFR/COL1A1/PTPN6/COL1A2/FZD2/VAV1/CDKN1A/PRKCB/GRB2/PLCG2/SDC4/GPC3/PAK1/HSPB2/FZD1/CTSL/TNF/HCLS1/MYC/RAC1/MAPK1/PPP1CA/CD44/WNT5A/PLAUR/TFAP4/PIK3R1/CTTN/PPP1R12B/HBEGF/GPC1/FAS/CAV2/NRAS/PIK3CA/TLR2/WNT11/PPP1CC/MMP9	41
KEGG	hsa05160	Hepatitis C	33/1069	157/8135	0.003739	0.01538	0.009889	EGFR/CDKN1A/IFNAR2/GRB2/CLDN5/BAK1/STAT1/OAS1/MX2/OAS2/LDLR/TNF/CLDN7/TRAF3/MYC/NFKB1/MAPK1/IKBKE/CXCL10/YWHAB/EIF2AK2/PIK3R1/BID/SOCS3/CDK4/CDK2/FAS/NRAS/PIK3CA/RB1/IFNG/MX1/FADD	33
KEGG	hsa04510	Focal adhesion	40/1069	201/8135	0.004232	0.01719	0.01106	RAC2/EGFR/COL1A1/SPP1/COL1A2/ITGB7/MYL9/VAV1/PRKCB/LAMA2/GRB2/PAK1/JUN/ITGA7/LAMA3/ITGA4/PARVA/MAPK10/ACTN4/VASP/MYLK/RAC1/THBS2/MAPK1/PPP1CA/TLN2/MYL2/VEGFC/BIRC3/THBS3/PIK3R1/LAMB2/PPP1R12B/TNC/PAK2/CAV2/PIK3CA/RAPGEF1/VEGFB/PPP1CC	40
KEGG	hsa04923	Regulation of lipolysis in adipocytes	15/1069	56/8135	0.004677	0.01876	0.01207	FABP4/PLIN1/LIPE/PTGER3/NPR1/PDE3B/IRS1/ADCY7/PNPLA2/ADORA1/MGLL/ADCY6/PIK3R1/PIK3CA/PRKG1	15
KEGG	hsa04015	Rap1 signaling pathway	41/1069	210/8135	0.005401	0.02141	0.01377	RAC2/MAPK13/EGFR/MAGI2/ITGAL/VAV1/PRKCB/ITGB2/LCP2/ID1/CNR1/RAPGEF3/ADCY7/PLCB2/PLCB1/SKAP1/LAT/VASP/CALM1/RAC1/MAPK1/ITGAM/PARD3/TLN2/DOCK4/VEGFC/PFN1/ADCY6/PIK3R1/EFNA1/FPR1/RALA/NRAS/PIK3CA/FGFR2/RAPGEF1/VEGFB/EFNA5/MAP2K6/F2R/ANGPT1	41
KEGG	hsa04722	Neurotrophin signaling pathway	26/1069	119/8135	0.005583	0.02186	0.01406	MAPK13/RPS6KA1/ATF4/FOXO3/ARHGDIB/GRB2/PLCG2/NFKBIE/JUN/SH2B3/IRS1/MATK/MAPK10/CALM1/RAC1/NFKB1/MAPK1/PSEN1/NTRK3/RPS6KA2/PIK3R1/MAPK7/NRAS/PIK3CA/PSEN2/RAPGEF1	26
KEGG	hsa04010	MAPK signaling pathway	54/1069	294/8135	0.005952	0.02304	0.01482	RAC2/IL1R1/MAPK13/HSPB1/EGFR/GADD45A/RPS6KA1/TGFA/ATF4/PTPN7/GADD45B/PRKCB/DDIT3/GRB2/MYD88/HSPA6/PAK1/RASGRP1/JUN/MAP4K1/ARRB2/CD14/JUND/RELB/DUSP4/TNF/MAPK10/MAP3K4/MYC/RAC1/NFKB1/MAPK1/CACNB3/DUSP1/STMN1/MKNK1/VEGFC/RPS6KA2/DAXX/EFNA1/MAPK7/GADD45G/CDC25B/FAS/PAK2/NRAS/FGFR2/DUSP3/VEGFB/EFNA5/NR4A1/MAP2K6/CACNA2D2/ANGPT1	54
KEGG	hsa04610	Complement and coagulation cascades	20/1069	85/8135	0.006065	0.0232	0.01492	C6/C2/ITGB2/ITGAX/CFB/CFH/SERPINA5/CFD/C3AR1/SERPINA1/PLAT/C1QB/ITGAM/PLAUR/CD55/C7/SERPING1/BDKRB2/F2R/SERPINF2	20
KEGG	hsa05161	Hepatitis B	33/1069	162/8135	0.006182	0.02328	0.01497	MAPK13/ATF4/CDKN1A/PRKCB/PCNA/GRB2/MYD88/CREB3L2/JUN/STAT1/CCNA2/TNF/MAPK10/TRAF3/MYC/NFKB1/MAPK1/STAT4/DDB2/SMAD3/IKBKE/YWHAB/PIK3R1/BID/CDK2/FAS/NRAS/PIK3CA/TLR2/RB1/MAP2K6/FADD/MMP9	33
KEGG	hsa03250	Viral life cycle - HIV-1	16/1069	63/8135	0.006227	0.02328	0.01497	CD4/APOBEC3G/APOBEC3C/MX2/CXCR4/CCR5/MAP1B/HGS/CCNT1/KAT2A/BICD2/SUPT5H/SERINC5/SAMHD1/CDK9/MX1	16
KEGG	hsa04066	HIF-1 signaling pathway	24/1069	109/8135	0.006851	0.02532	0.01629	EGFR/TIMP1/TF/HK3/CDKN1A/PRKCB/EIF4E2/PLCG2/NFKB1/MAPK1/PFKM/LDHB/MKNK1/HMOX1/PIK3R1/TFRC/EIF4EBP1/PIK3CA/IFNG/IFNGR2/PFKFB3/ANGPT1/PDHA1/CYBB	24
KEGG	hsa05222	Small cell lung cancer	21/1069	92/8135	0.007217	0.02638	0.01697	GADD45A/CDKN1A/GADD45B/LAMA2/BAK1/LAMA3/TRAF1/TRAF3/MYC/NFKB1/DDB2/CKS1B/BIRC3/PIK3R1/LAMB2/GADD45G/CKS2/CDK4/CDK2/PIK3CA/RB1	21
KEGG	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	17/1069	70/8135	0.007882	0.0285	0.01833	CCL5/MAPK13/EGFR/CSK/PLCG2/PAK1/JUN/MAPK10/RAC1/NFKB1/ADAM10/CXCL1/LYN/TCIRG1/HBEGF/JAM3/ATP6V1A	17
KEGG	hsa05131	Shigellosis	46/1069	247/8135	0.00825	0.0295	0.01897	CCL5/IL1R1/MAPK13/EGFR/FOXO1/FOXO3/MYL9/HK3/PLCG2/MYD88/ARPC1B/JUN/ARPC2/CD14/PLCB2/PLCB1/CYTH1/TNF/MAPK10/SQSTM1/HCLS1/ARPC3/FNBP1L/CASP4/ARPC5/ACTN4/RAC1/NFKB1/MAPK1/FNBP1/CD44/TLN2/MYL2/PFN1/PIK3R1/IL18/CTTN/FOXO4/UBE2D2/CASP1/ARF6/UBC/PIK3CA/ACTR3/MAP1LC3B/NLRP3	46
KEGG	hsa05220	Chronic myeloid leukemia	18/1069	76/8135	0.008355	0.02956	0.01901	GADD45A/CDKN1A/GADD45B/GRB2/BAK1/HDAC1/MYC/NFKB1/MAPK1/DDB2/SMAD3/BCR/PIK3R1/GADD45G/CDK4/NRAS/PIK3CA/RB1	18
KEGG	hsa04520	Adherens junction	17/1069	71/8135	0.009131	0.03196	0.02055	RAC2/EGFR/PTPN6/TCF7L2/WASF3/TCF7/BAIAP2/ACTN4/RAC1/MAPK1/SMAD3/PARD3/PTPRJ/SORBS1/CSNK2A2/PTPRF/LEF1	17
KEGG	hsa04211	Longevity regulating pathway	20/1069	89/8135	0.01028	0.03559	0.02289	ADIPOQ/FOXO1/ADIPOR2/ATF4/FOXO3/PPARG/EIF4E2/CREB3L2/IRS1/ADCY7/NFKB1/RB1CC1/ADCY6/PIK3R1/EHMT2/EIF4EBP1/NRAS/PIK3CA/ULK1/STK11	20
KEGG	hsa04012	ErbB signaling pathway	19/1069	85/8135	0.01288	0.04415	0.02839	EGFR/TGFA/CBLB/CDKN1A/PRKCB/GRB2/PLCG2/PAK1/JUN/MAPK10/MYC/MAPK1/PIK3R1/HBEGF/ABL2/EIF4EBP1/PAK2/NRAS/PIK3CA	19
KEGG	hsa03010	Ribosome	31/1069	158/8135	0.01336	0.0453	0.02913	FAU/RPL34/RPS5/RPL35/RPS25/RPL8/RPL13/RPL12/RPL18/RPS15/RPL14/RPL10A/RPL24/RPL9/RPL31/RPS16/RPL27/RPS12/RPLP0/RPS4Y1/RPL29/RPS10/RPL30/RPL37/RPL11/RPS17/RPL38/RPL32/RPL19/RPS28/RPL39	31
KEGG	hsa05219	Bladder cancer	11/1069	41/8135	0.01428	0.04762	0.03062	EGFR/CDKN1A/MMP1/TYMP/MYC/MAPK1/HBEGF/CDK4/NRAS/RB1/MMP9	11
KEGG	hsa04621	NOD-like receptor signaling pathway	35/1069	184/8135	0.01433	0.04762	0.03062	CCL5/GABARAPL1/MAPK13/IFNAR2/TXNIP/MYD88/JUN/STAT1/CYBA/OAS1/PSTPIP1/OAS2/AIM2/PLCB2/PLCB1/TNF/MAPK10/GBP1/TRAF3/CASP4/NFKB1/MAPK1/IKBKE/GBP2/CXCL1/BIRC3/IL18/CASP1/HSP90AB1/PANX1/MAP1LC3B/TP53BP1/NLRP3/FADD/CYBB	35
KEGG	hsa04625	C-type lectin receptor signaling pathway	22/1069	104/8135	0.01492	0.04909	0.03157	MAPK13/CBLB/PLCG2/PAK1/JUN/STAT1/RELB/SYK/TNF/MAPK10/IL10/CALM1/FCER1G/NFKB1/MAPK1/IKBKE/PIK3R1/CASP1/PLK3/NRAS/PIK3CA/NLRP3	22
KEGG	hsa04932	Non-alcoholic fatty liver disease	30/1069	155/8135	0.01771	0.05768	0.0371	ADIPOQ/MAPK13/ADIPOR2/SREBF1/ATF4/PPARG/DDIT3/JUN/COX7A1/IRS1/XBP1/TNF/MAPK10/NDUFV1/NDUFS7/RAC1/NFKB1/NDUFB7/NDUFS5/PIK3R1/BID/SOCS3/FAS/NDUFC1/PIK3CA/UQCRFS1/NDUFB5/NDUFS6/NDUFAB1/COX6A2	30
KEGG	hsa05143	African trypanosomiasis	10/1069	37/8135	0.01812	0.05837	0.03754	PRKCB/MYD88/PLCB2/PLCB1/TNF/APOL1/IL10/IL18/FAS/IFNG	10
KEGG	hsa05225	Hepatocellular carcinoma	32/1069	168/8135	0.01827	0.05837	0.03754	EGFR/GADD45A/TGFA/TCF7L2/FZD2/CDKN1A/NQO1/GADD45B/PRKCB/GRB2/PLCG2/TCF7/BAK1/FZD1/MYC/MAPK1/LRP5/DDB2/SMAD3/WNT5A/HMOX1/PIK3R1/GADD45G/SMARCD3/CDK4/NRAS/PIK3CA/WNT11/RB1/GSTM3/GSTO1/LEF1	32
KEGG	hsa04630	JAK-STAT signaling pathway	31/1069	162/8135	0.01877	0.05938	0.03819	EGFR/IL2RG/PTPN6/IL2RB/SOCS2/CDKN1A/IFNAR2/GRB2/IL10RA/IL7R/STAT1/CSF2RB/CSF2RA/AOX1/IL27RA/IL10/MYC/STAT4/PIM1/IL15/IL15RA/IL4R/LIFR/SOCS6/FHL1/GFAP/PIK3R1/SOCS3/PIK3CA/IFNG/IFNGR2	31
KEGG	hsa05020	Prion disease	48/1069	273/8135	0.0199	0.06236	0.0401	CCL5/RAC2/C6/MAPK13/ATF4/DDIT3/HSPA6/CREB3L2/COX7A1/CYBA/PSMA5/PSMC5/EGR1/TNF/NCF2/MAPK10/PSMC3/NDUFV1/NDUFS7/RAC1/MAPK1/NDUFB7/C1QB/NDUFS5/SOD1/KLC1/TUBB/PIK3R1/CSNK2A2/PSMD8/SLC25A6/NCF4/HSPA5/C7/NDUFC1/CAV2/PIK3CA/KIF5C/PSMC2/PRNP/UQCRFS1/NDUFB5/PPIF/NDUFS6/PSMB2/NDUFAB1/COX6A2/CYBB	48
KEGG	hsa00071	Fatty acid degradation	11/1069	43/8135	0.02035	0.06317	0.04062	ADH1A/ADH1B/ADH1C/HADH/ACADS/ECHS1/ECI1/ACSL1/ACADVL/ADH5/ACAT2	11
KEGG	hsa04931	Insulin resistance	22/1069	108/8135	0.0226	0.06948	0.04468	PCK1/FOXO1/RPS6KA1/SREBF1/PRKCB/CREB3L2/IRS1/PPP1R3C/TNF/MAPK10/SLC2A4/NFKB1/ACACB/PPP1CA/RPS6KA2/PIK3R1/SLC27A2/SOCS3/PTPRF/PIK3CA/AGT/PPP1CC	22
KEGG	hsa05165	Human papillomavirus infection	56/1069	331/8135	0.02588	0.07885	0.05071	EGFR/COL1A1/FOXO1/TCF7L2/HLA-F/SPP1/COL1A2/ITGB7/FZD2/CDKN1A/IFNAR2/LAMA2/GRB2/TCF7/CREB3L2/BAK1/STAT1/FZD1/HDAC1/ITGA7/CCNA2/LAMA3/HES1/MX2/ITGA4/TNF/TRAF3/JAG1/THBS2/NFKB1/MAPK1/IKBKE/HLA-G/PSEN1/PARD3/WNT5A/HLA-A/TCIRG1/EIF2AK2/THBS3/PIK3R1/LAMB2/CDK4/EIF4EBP1/CDK2/FAS/TNC/NRAS/PIK3CA/WNT11/RB1/PPP2R5C/ATP6V1A/MX1/FADD/PTGER4	56
KEGG	hsa04310	Wnt signaling pathway	31/1069	167/8135	0.02784	0.08403	0.05404	RAC2/TCF7L2/FZD2/PRKCB/TCF7/JUN/GPC4/FZD1/SFRP4/WIF1/PLCB2/PLCB1/MAPK10/MYC/DAAM2/SFRP1/RAC1/LRP5/SMAD3/PSEN1/WNT5A/TLE2/CSNK2A2/TLE1/RYK/MMP7/TLE4/ROR1/WNT11/LEF1/CBY1	31
KEGG	hsa05134	Legionellosis	13/1069	57/8135	0.03084	0.09225	0.05933	ITGB2/MYD88/HSPA6/EEF1A2/CD14/TNF/NFKB1/ITGAM/CXCL1/IL18/CASP1/TLR2/HSF1	13
KEGG	hsa05217	Basal cell carcinoma	14/1069	63/8135	0.03157	0.09287	0.05972	GADD45A/TCF7L2/FZD2/CDKN1A/GADD45B/TCF7/BAK1/FZD1/BMP4/DDB2/WNT5A/GADD45G/WNT11/LEF1	14
KEGG	hsa04912	GnRH signaling pathway	19/1069	93/8135	0.03161	0.09287	0.05972	MAPK13/EGFR/ATF4/PRKCB/GRB2/JUN/ADCY7/PLCB2/PLCB1/EGR1/MAPK10/MAP3K4/CALM1/MAPK1/ADCY6/HBEGF/MAPK7/NRAS/MAP2K6	19
KEGG	hsa03050	Proteasome	11/1069	46/8135	0.03275	0.09451	0.06078	PSMB9/PSMB10/PSMB8/PSMA5/PSMC5/PSMC3/PSME1/PSMD8/PSMC2/IFNG/PSMB2	11
KEGG	hsa04930	Type II diabetes mellitus	11/1069	46/8135	0.03275	0.09451	0.06078	ADIPOQ/SOCS2/HK3/IRS1/TNF/MAPK10/SLC2A4/MAPK1/PIK3R1/SOCS3/PIK3CA	11
KEGG	hsa04261	Adrenergic signaling in cardiomyocytes	28/1069	150/8135	0.03307	0.0946	0.06083	AGTR1/MAPK13/ATF4/TPM2/CREB3L2/PPP1R1A/RAPGEF3/ADCY7/PLCB2/PLCB1/PLN/TPM4/CALM1/MAPK1/CACNB3/ACTC1/PPP1CA/ATP1A1/MYL2/ADCY6/SCN7A/MYH7/CREM/MYL3/AGT/PPP2R5C/CACNA2D2/PPP1CC	28
KEGG	hsa05208	Chemical carcinogenesis - reactive oxygen species	39/1069	223/8135	0.03594	0.1019	0.06554	MAPK13/EGFR/FOXO3/NQO1/GRB2/JUN/AKR1A1/COX7A1/CYBA/AKR1C3/NCF2/MAPK10/NDUFV1/NDUFS7/RAC1/NFKB1/MAPK1/NDUFB7/NDUFS5/LPO/SOD1/HMOX1/PTPRJ/PIK3R1/ABL2/EPHX1/SLC25A6/NDUFC1/NRAS/PIK3CA/GSTM3/UQCRFS1/NDUFB5/PPIF/NDUFS6/CBR1/NDUFAB1/GSTO1/COX6A2	39
KEGG	hsa05022	Pathways of neurodegeneration - multiple diseases	76/1069	476/8135	0.03757	0.1057	0.06795	MAPK13/ATF4/GPX3/FZD2/PRKCB/DDIT3/BAK1/COX7A1/UBE2L6/FZD1/PINK1/XBP1/PSMA5/PSMC5/UBE2G2/PLCB2/PLCB1/RAB8A/TNF/MAPK10/SQSTM1/PSMC3/TNFRSF1B/NDUFV1/SLC6A3/CALM1/NDUFS7/RAC1/NFKB1/MAPK1/LRP5/NDUFB7/TRAP1/PSEN1/RB1CC1/NDUFS5/WNT5A/SOD1/CDK5/DCTN3/KLC1/TUBB/CSNK2A2/DAXX/UBE2G1/UBE2J1/HIP1/PSMD8/BID/SLC25A6/HSPA5/FIG4/FAS/UBC/NDUFC1/NRAS/UCHL1/ULK1/PSEN2/WNT11/KIF5C/PARK7/PSMC2/PRNP/MAP1LC3B/UQCRFS1/NDUFB5/MAP2K6/PPIF/NDUFS6/PSMB2/SPG11/NDUFAB1/FADD/COX6A2/CYBB	76
KEGG	hsa00100	Steroid biosynthesis	6/1069	20/8135	0.03854	0.1074	0.0691	DHCR24/DHCR7/TM7SF2/NSDHL/FDFT1/LIPA	6
KEGG	hsa04144	Endocytosis	43/1069	251/8135	0.03893	0.1076	0.06922	EGFR/IL2RG/IL2RB/HLA-F/CBLB/BIN1/HSPA6/ARPC1B/ARPC2/AMPH/GRK5/ARRB2/DNM1/PSD4/CAPZB/LDLR/CXCR4/CCR5/RAB8A/CYTH1/HGS/SH3GL2/ARPC3/ARPC5/ARAP1/SMAD3/HLA-G/CLTCL1/PARD3/HLA-A/RAB31/FOLR2/CLTB/TFRC/ARF6/CAV2/ACTR3/FGFR2/KIF5C/SMURF2/IGF2R/ACAP1/SH3GL1	43
KEGG	hsa04914	Progesterone-mediated oocyte maturation	20/1069	102/8135	0.0414	0.1131	0.07271	MAPK13/CCNB1/RPS6KA1/PDE3B/CCNA2/ADCY7/STK10/MAPK10/CCNB2/MAPK1/PLK1/RPS6KA2/ADCY6/PIK3R1/HSP90AB1/CDC25B/CDK2/MAD2L1/PIK3CA/PKMYT1	20
KEGG	hsa04151	PI3K-Akt signaling pathway	58/1069	354/8135	0.04158	0.1131	0.07271	PCK1/EGFR/COL1A1/IL2RG/MAGI2/IL2RB/TGFA/ATF4/SPP1/COL1A2/FOXO3/ITGB7/PHLPP1/CDKN1A/EIF4E2/IFNAR2/LAMA2/GRB2/IL7R/CREB3L2/DDIT4/IRS1/ITGA7/LAMA3/SYK/ITGA4/MYC/RAC1/THBS2/NFKB1/MAPK1/IL4R/VEGFC/YWHAB/THBS3/PIK3R1/LAMB2/EFNA1/GNG11/HSP90AB1/CDK4/EIF4EBP1/CDK2/TNC/CD19/NRAS/PIK3CA/TLR2/FGFR2/TCL1A/VEGFB/EFNA5/STK11/NR4A1/PPP2R5C/GNG5/F2R/ANGPT1	58
KEGG	hsa05414	Dilated cardiomyopathy	19/1069	96/8135	0.04232	0.1141	0.07339	ITGB7/DES/LAMA2/TPM2/ITGA7/ADCY7/EMD/ITGA4/TNF/PLN/TPM4/CACNB3/ACTC1/MYL2/ADCY6/MYH7/MYL3/AGT/CACNA2D2	19
KEGG	hsa05224	Breast cancer	27/1069	147/8135	0.0429	0.1148	0.0738	EGFR/GADD45A/TCF7L2/FZD2/CDKN1A/GADD45B/GRB2/TCF7/BAK1/JUN/FZD1/HES1/TNFSF11/JAG1/MYC/MAPK1/LRP5/DDB2/WNT5A/PIK3R1/GADD45G/CDK4/NRAS/PIK3CA/WNT11/RB1/LEF1	27
KEGG	hsa04978	Mineral absorption	13/1069	60/8135	0.04502	0.1194	0.07681	MT1X/MT1B/TF/MT1A/VDR/MT1F/MT1H/MT1E/SLC31A1/STEAP1/ATP1A1/HMOX1/MT2A	13
KEGG	hsa00790	Folate biosynthesis	7/1069	26/8135	0.04576	0.1204	0.07745	AKR1C3/AKR1B10/MOCS1/ALPL/AKR1B1/GGH/CBR1	7
KEGG	hsa05322	Systemic lupus erythematosus	25/1069	136/8135	0.04953	0.1284	0.08259	HLA-DRB4/C6/HLA-DMA/HLA-DMB/HLA-DOB/C2/CD40/FCGR3B/FCGR3A/HLA-DPB1/FCGR2A/CD86/HLA-DPA1/HLA-DOA/TNF/ACTN4/IL10/C1QB/SNRPD1/HLA-DRA/CD28/TRIM21/ELANE/C7/IFNG	25
KEGG	hsa00562	Inositol phosphate metabolism	15/1069	73/8135	0.04996	0.1284	0.08259	INPP5D/ALDH6A1/PLCG2/PLCB2/PLCB1/ITPKC/PI4K2A/MINPP1/IMPA2/SYNJ2/FIG4/PIK3CA/INPP5K/ITPK1/MTMR1	15
KEGG	hsa01524	Platinum drug resistance	15/1069	73/8135	0.04996	0.1284	0.08259	CDKN1A/BAK1/REV3L/TOP2A/MAPK1/SLC31A1/BIRC3/PIK3R1/BID/FAS/PIK3CA/ERCC1/GSTM3/FADD/GSTO1	15
KEGG	hsa04613	Neutrophil extracellular trap formation	33/1069	190/8135	0.05476	0.1397	0.08982	RAC2/MAPK13/ITGAL/PRKCB/ITGB2/SELPLG/PLCG2/FCGR3B/AQP9/FCGR3A/CYBA/HDAC1/FCGR2A/SYK/PLCB2/PLCB1/NCF2/CASP4/RAC1/NFKB1/MAPK1/FPR3/ITGAM/PIK3R1/CASP1/SLC25A6/NCF4/FPR1/ELANE/PIK3CA/TLR2/PPIF/CYBB	33
KEGG	hsa04213	Longevity regulating pathway - multiple species	13/1069	62/8135	0.05667	0.1434	0.09223	CRYAB/FOXO1/FOXO3/HSPA6/IRS1/HDAC1/ADCY7/EIF4EBP2/SOD1/ADCY6/PIK3R1/NRAS/PIK3CA	13
KEGG	hsa00051	Fructose and mannose metabolism	8/1069	33/8135	0.05937	0.1491	0.09589	HK3/AKR1B10/PFKFB1/ENOSF1/PFKM/AKR1B1/PMM1/PFKFB3	8
KEGG	hsa05012	Parkinson disease	44/1069	266/8135	0.06064	0.1512	0.0972	MAOA/ATF4/DDIT3/COX7A1/UBE2L6/PINK1/XBP1/PSMA5/PSMC5/SLC39A14/UBE2G2/MAPK10/PSMC3/NDUFV1/SLC6A3/CALM1/NDUFS7/SLC39A8/NDUFB7/TRAP1/DUSP1/NDUFS5/SOD1/KLC1/TUBB/DAXX/UBE2G1/UBE2J1/PSMD8/SLC25A6/HSPA5/UBC/NDUFC1/UCHL1/KIF5C/PARK7/PSMC2/UQCRFS1/NDUFB5/PPIF/NDUFS6/PSMB2/NDUFAB1/COX6A2	44
KEGG	hsa03320	PPAR signaling pathway	15/1069	75/8135	0.06119	0.1514	0.09734	SCD/PCK1/FABP4/ADIPOQ/LPL/PLIN1/PPARG/PLIN2/MMP1/PLTP/ACSL1/SORBS1/GK/SLC27A2/UBC	15
KEGG	hsa04920	Adipocytokine signaling pathway	14/1069	69/8135	0.06231	0.153	0.09838	PCK1/ADIPOQ/ADIPOR2/NFKBIE/IRS1/TNF/MAPK10/TNFRSF1B/SLC2A4/NFKB1/ACACB/ACSL1/SOCS3/STK11	14
KEGG	hsa01212	Fatty acid metabolism	12/1069	57/8135	0.06375	0.1545	0.09934	FASN/SCD/PPT1/HADH/ACADS/ECHS1/ACSL1/ACADVL/ELOVL5/ACACA/TECR/ACAT2	12
KEGG	hsa00270	Cysteine and methionine metabolism	11/1069	51/8135	0.06386	0.1545	0.09934	CDO1/MPST/PHGDH/CTH/CBS/LDHB/TST/BCAT2/AHCYL1/DNMT1/GCLM	11
KEGG	hsa04917	Prolactin signaling pathway	14/1069	70/8135	0.0689	0.1632	0.105	MAPK13/SOCS2/FOXO3/GRB2/STAT1/TNFSF11/MAPK10/NFKB1/MAPK1/SOCS6/PIK3R1/SOCS3/NRAS/PIK3CA	14
KEGG	hsa05230	Central carbon metabolism in cancer	14/1069	70/8135	0.0689	0.1632	0.105	EGFR/HK3/IDH2/SLC1A5/MYC/MAPK1/PFKM/LDHB/NTRK3/PIK3R1/NRAS/PIK3CA/FGFR2/PDHA1	14
KEGG	hsa04919	Thyroid hormone signaling pathway	22/1069	121/8135	0.06896	0.1632	0.105	FOXO1/MED13L/PRKCB/PLCG2/STAT1/HDAC1/THRA/PLCB2/PLCB1/BMP4/PLN/MYC/KAT2A/MAPK1/PFKM/ATP1A1/DIO3/RCAN1/PIK3R1/MYH7/NRAS/PIK3CA	22
KEGG	hsa00260	Glycine, serine and threonine metabolism	9/1069	40/8135	0.07105	0.1665	0.1071	MAOA/AOC3/PHGDH/CTH/GATM/CBS/AOC2/SHMT2/GRHPR	9
KEGG	hsa00230	Purine metabolism	23/1069	128/8135	0.07137	0.1665	0.1071	NPR1/PDE3B/ADCY7/PAPSS2/AMPD3/IMPDH2/NT5E/IMPDH1/AMPD1/PAPSS1/PDE8B/PDE9A/ADCY6/DCK/ENTPD1/PDE2A/PDE6D/HDDC2/PGM1/PDE1B/APRT/PDE1A/HPRT1	23
KEGG	hsa05100	Bacterial invasion of epithelial cells	15/1069	77/8135	0.074	0.1715	0.1103	ARPC1B/ARPC2/DNM1/HCLS1/ARPC3/RHOG/ARPC5/RAC1/CLTCL1/PIK3R1/CTTN/CLTB/CAV2/PIK3CA/ACTR3	15
KEGG	hsa04530	Tight junction	29/1069	169/8135	0.07741	0.1781	0.1145	YBX3/MYL9/PCNA/TJP2/CLDN5/ARPC1B/JUN/ARPC2/AMOT/WHAMM/MYH11/RAB8A/MAPK10/CLDN7/HCLS1/ARPC3/ARPC5/ACTN4/VASP/RAC1/PARD3/AMOTL2/MYL2/CTTN/ARHGEF18/CDK4/ACTR3/JAM3/STK11	29
KEGG	hsa04961	Endocrine and other factor-regulated calcium reabsorption	11/1069	53/8135	0.08038	0.1836	0.1181	VDR/PRKCB/DNM1/PLCB2/PLCB1/CLTCL1/ATP1A1/ADCY6/CLTB/PTH1R/BDKRB2	11
KEGG	hsa01522	Endocrine resistance	18/1069	98/8135	0.08634	0.1959	0.126	MAPK13/EGFR/CDKN1A/GRB2/JUN/ADCY7/MAPK10/JAG1/MAPK1/ADCY6/PIK3R1/CDKN2C/HBEGF/CDK4/NRAS/PIK3CA/RB1/MMP9	18
KEGG	hsa04115	p53 signaling pathway	14/1069	73/8135	0.09135	0.2058	0.1324	CCNB1/GADD45A/CDKN1A/GADD45B/TP53I3/CCNB2/DDB2/EI24/GADD45G/BID/CDK4/CDK2/FAS/CCNG2	14
KEGG	hsa04720	Long-term potentiation	13/1069	67/8135	0.09417	0.2108	0.1355	RPS6KA1/ATF4/PRKCB/PPP1R1A/RAPGEF3/PLCB2/PLCB1/CALM1/MAPK1/PPP1CA/RPS6KA2/NRAS/PPP1CC	13
KEGG	hsa04935	Growth hormone synthesis, secretion and action	21/1069	119/8135	0.09526	0.2118	0.1362	MAPK13/SOCS2/ATF4/PRKCB/GRB2/PLCG2/CREB3L2/STAT1/IRS1/ADCY7/PLCB2/PLCB1/MAPK10/MAPK1/ADCY6/PIK3R1/SOCS3/NRAS/PIK3CA/JUNB/MAP2K6	21
KEGG	hsa04928	Parathyroid hormone synthesis, secretion and action	19/1069	106/8135	0.09644	0.2124	0.1366	EGFR/ATF4/VDR/CDKN1A/PRKCB/CREB3L2/ARRB2/ADCY7/JUND/TNFSF11/PLCB2/PLCB1/EGR1/MAPK1/LRP5/GATA3/ADCY6/HBEGF/PTH1R	19
KEGG	hsa00561	Glycerolipid metabolism	12/1069	61/8135	0.09686	0.2124	0.1366	LPL/AGPAT2/AKR1A1/LPIN1/AKR1B10/PNPLA2/MGLL/DGAT1/GLA/GK/AKR1B1/AGPAT1	12
KEGG	hsa04022	cGMP-PKG signaling pathway	28/1069	167/8135	0.1019	0.222	0.1428	AGTR1/ATF4/MYL9/CREB3L2/NPR1/PDE3B/IRS1/ADCY7/EDNRB/PLCB2/PLCB1/PLN/VASP/CALM1/MYLK/ADORA1/MAPK1/PPP1CA/ATP1A1/ADCY6/PDE2A/MYH7/SLC25A6/ADRA2A/BDKRB2/PRKG1/PPIF/PPP1CC	28
KEGG	hsa04960	Aldosterone-regulated sodium reabsorption	8/1069	37/8135	0.1037	0.2245	0.1444	PRKCB/IRS1/MAPK1/ATP1A1/SLC9A3R2/PIK3R1/SCNN1B/PIK3CA	8
KEGG	hsa04270	Vascular smooth muscle contraction	23/1069	134/8135	0.1063	0.2285	0.1469	AGTR1/ADM/MYL9/PRKCB/RAMP2/NPR1/ADCY7/MYH11/PLCB2/PLCB1/CALM1/MYLK/MAPK1/PPP1CA/ADCY6/PPP1R12B/AGT/RAMP1/AVPR1A/PRKG1/ACTG2/PPP1CC/ACTA2	23
KEGG	hsa04512	ECM-receptor interaction	16/1069	88/8135	0.1089	0.2326	0.1496	SDC1/COL1A1/SPP1/COL1A2/ITGB7/LAMA2/SDC4/ITGA7/LAMA3/ITGA4/THBS2/CD44/THBS3/LAMB2/TNC/AGRN	16
KEGG	hsa04360	Axon guidance	30/1069	182/8135	0.1098	0.2331	0.1499	RAC2/MYL9/PLXNB2/PLCG2/PLXNC1/PAK1/ABLIM1/CXCR4/SEMA3E/RAC1/MAPK1/EPHA4/PARD3/WNT5A/ABLIM3/CDK5/PIK3R1/EFNA1/RYK/CXCL12/SLIT3/PAK2/NRAS/PIK3CA/UNC5B/PLXNA2/SEMA3C/EPHB2/EFNA5/RND1	30
KEGG	hsa04934	Cushing syndrome	26/1069	155/8135	0.1112	0.2346	0.1509	AGTR1/EGFR/TCF7L2/ATF4/FZD2/CDKN1A/TCF7/CREB3L2/FZD1/ADCY7/LDLR/PLCB2/PLCB1/MAPK1/PDE8B/WNT5A/ADCY6/CDKN2C/ASH2L/CDK4/CDK2/WNT11/AGT/RB1/NR4A1/LEF1	26
KEGG	hsa05226	Gastric cancer	25/1069	149/8135	0.1163	0.2436	0.1567	EGFR/GADD45A/TCF7L2/FZD2/CDKN1A/GADD45B/GRB2/TCF7/BAK1/FZD1/MYC/MAPK1/LRP5/DDB2/SMAD3/WNT5A/PIK3R1/GADD45G/CDK2/NRAS/PIK3CA/FGFR2/WNT11/RB1/LEF1	25
KEGG	hsa04150	mTOR signaling pathway	26/1069	156/8135	0.1176	0.2437	0.1567	RPS6KA1/FZD2/PRKCB/EIF4E2/GRB2/LPIN1/DDIT4/FZD1/IRS1/TNF/MAPK1/LRP5/MAPKAP1/NPRL3/WNT5A/RPS6KA2/PIK3R1/EIF4EBP1/SLC3A2/NRAS/PIK3CA/ULK1/WNT11/STK11/LAMTOR5/ATP6V1A	26
KEGG	hsa00640	Propanoate metabolism	7/1069	32/8135	0.1178	0.2437	0.1567	ALDH6A1/ACADS/ECHS1/BCKDHA/ACACB/LDHB/ACACA	7
KEGG	hsa00603	Glycosphingolipid biosynthesis - globo and isoglobo series	4/1069	15/8135	0.1239	0.2548	0.1638	NAGA/GLA/HEXA/ST3GAL2	4
KEGG	hsa05410	Hypertrophic cardiomyopathy	16/1069	90/8135	0.1263	0.2582	0.166	ITGB7/DES/LAMA2/TPM2/ITGA7/EMD/ITGA4/TNF/TPM4/CACNB3/ACTC1/MYL2/MYH7/MYL3/AGT/CACNA2D2	16
KEGG	hsa00062	Fatty acid elongation	6/1069	27/8135	0.1341	0.2723	0.1751	PPT1/HADH/ECHS1/ACOT7/ELOVL5/TECR	6
KEGG	hsa04750	Inflammatory mediator regulation of TRP channels	17/1069	98/8135	0.1388	0.2785	0.1791	IL1R1/MAPK13/PRKCB/PLCG2/ADCY7/PLCB2/PLCB1/MAPK10/CALM1/PPP1CA/ADCY6/PIK3R1/PIK3CA/BDKRB2/MAP2K6/PTGER4/PPP1CC	17
KEGG	hsa04925	Aldosterone synthesis and secretion	17/1069	98/8135	0.1388	0.2785	0.1791	AGTR1/ATF4/LIPE/PRKCB/CREB3L2/NPR1/ADCY7/LDLR/PLCB2/PLCB1/CALM1/CAMK1/ATP1A1/ADCY6/PDE2A/AGT/NR4A1	17
KEGG	hsa04371	Apelin signaling pathway	23/1069	139/8135	0.1424	0.2839	0.1826	AGTR1/PLIN1/SPP1/LIPE/PDE3B/ADCY7/PLCB2/PLCB1/EGR1/JAG1/CALM1/MYLK/MAPK1/PLAT/SMAD3/MYL2/ADCY6/GNG11/NRAS/MYL3/MAP1LC3B/GNG5/ACTA2	23
KEGG	hsa05218	Melanoma	13/1069	72/8135	0.144	0.2846	0.183	EGFR/GADD45A/CDKN1A/GADD45B/BAK1/MAPK1/DDB2/PIK3R1/GADD45G/CDK4/NRAS/PIK3CA/RB1	13
KEGG	hsa04370	VEGF signaling pathway	11/1069	59/8135	0.1445	0.2846	0.183	RAC2/MAPK13/HSPB1/PRKCB/PLCG2/SH2D2A/RAC1/MAPK1/PIK3R1/NRAS/PIK3CA	11
KEGG	hsa01521	EGFR tyrosine kinase inhibitor resistance	14/1069	79/8135	0.1485	0.2899	0.1864	EGFR/TGFA/FOXO3/PRKCB/EIF4E2/AXL/GRB2/PLCG2/MAPK1/PIK3R1/EIF4EBP1/NRAS/PIK3CA/FGFR2	14
KEGG	hsa00360	Phenylalanine metabolism	4/1069	16/8135	0.1489	0.2899	0.1864	MAOA/AOC3/AOC2/HPD	4
KEGG	hsa03020	RNA polymerase	7/1069	34/8135	0.1502	0.2906	0.1869	POLR2E/POLR2I/POLR2H/POLR2B/TWISTNB/POLR2J/POLR3C	7
KEGG	hsa04921	Oxytocin signaling pathway	25/1069	154/8135	0.1523	0.2931	0.1885	EGFR/MYL9/CDKN1A/PRKCB/JUN/NPR1/EEF2/ADCY7/PLCB2/PLCB1/CD38/CALM1/MYLK/MAPK1/CAMK1/CACNB3/PPP1CA/ADCY6/RCAN1/PPP1R12B/MAPK7/NRAS/OXT/CACNA2D2/PPP1CC	25
KEGG	hsa04072	Phospholipase D signaling pathway	24/1069	148/8135	0.1595	0.3051	0.1962	AGTR1/EGFR/AGPAT2/GRB2/PLCG2/RAPGEF3/DNM1/ADCY7/SYK/PLCB2/PLCB1/CYTH1/FCER1G/MAPK1/ADCY6/PIK3R1/ARF6/AGPAT1/RALA/NRAS/PIK3CA/AGT/AVPR1A/F2R	24
KEGG	hsa00010	Glycolysis / Gluconeogenesis	12/1069	67/8135	0.1627	0.3095	0.199	ADH1A/ADH1B/PCK1/ADH1C/HK3/AKR1A1/PFKM/LDHB/MINPP1/ADH5/PGM1/PDHA1	12
KEGG	hsa00130	Ubiquinone and other terpenoid-quinone biosynthesis	3/1069	11/8135	0.167	0.3145	0.2022	NQO1/HPD/COQ2	3
KEGG	hsa04020	Calcium signaling pathway	37/1069	240/8135	0.1674	0.3145	0.2022	AGTR1/EGFR/PTAFR/GNA15/PRKCB/PLCG2/PTGER3/ADCY7/CXCR4/EDNRB/P2RX4/PLCB2/PLCB1/PLN/CD38/CALM1/MYLK/CAMK1/NTRK3/ITPKC/P2RX5/ORAI2/VEGFC/STIM1/PHKA1/SLC25A6/PDE1B/PHKG1/FGFR2/VEGFB/PDE1A/AVPR1A/BDKRB2/PPIF/TNNC2/F2R/CASQ2	37
KEGG	hsa04916	Melanogenesis	17/1069	101/8135	0.1682	0.3145	0.2022	TCF7L2/FZD2/PRKCB/TCF7/CREB3L2/FZD1/ADCY7/EDNRB/PLCB2/PLCB1/CALM1/MAPK1/WNT5A/ADCY6/NRAS/WNT11/LEF1	17
KEGG	hsa01230	Biosynthesis of amino acids	13/1069	75/8135	0.1796	0.3338	0.2147	ASNS/ASS1/TKT/PC/IDH2/PHGDH/CTH/CBS/GLUL/PFKM/BCAT2/IDH3B/SHMT2	13
KEGG	hsa03030	DNA replication	7/1069	36/8135	0.1863	0.3443	0.2214	PCNA/POLD2/MCM5/LIG1/FEN1/MCM6/RPA1	7
KEGG	hsa04924	Renin secretion	12/1069	69/8135	0.1888	0.345	0.2219	AGTR1/NPR1/PDE3B/PLCB2/PLCB1/CALM1/ADORA1/ADCY6/PDE1B/PDE1A/AGT/PTGER4	12
KEGG	hsa05211	Renal cell carcinoma	12/1069	69/8135	0.1888	0.345	0.2219	TGFA/CDKN1A/GRB2/PAK1/JUN/RAC1/MAPK1/PIK3R1/PAK2/NRAS/PIK3CA/RAPGEF1	12
KEGG	hsa00020	Citrate cycle (TCA cycle)	6/1069	30/8135	0.1934	0.3497	0.2249	PCK1/PC/ACLY/IDH2/IDH3B/PDHA1	6
KEGG	hsa01523	Antifolate resistance	6/1069	30/8135	0.1934	0.3497	0.2249	TYMS/TNF/NFKB1/FOLR2/SHMT2/GGH	6
KEGG	hsa00061	Fatty acid biosynthesis	4/1069	18/8135	0.2039	0.3645	0.2344	FASN/ACACB/ACSL1/ACACA	4
KEGG	hsa00511	Other glycan degradation	4/1069	18/8135	0.2039	0.3645	0.2344	MAN2B1/MAN2B2/HEXA/AGA	4
KEGG	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	13/1069	77/8135	0.2055	0.3654	0.235	TCF7L2/ITGB7/DES/LAMA2/TCF7/ITGA7/EMD/ITGA4/CACNB3/GJA1/DSC2/CACNA2D2/LEF1	13
KEGG	hsa04929	GnRH secretion	11/1069	64/8135	0.2133	0.3764	0.242	SPP1/PRKCB/ARRB2/KCNN4/PLCB2/PLCB1/MAPK1/KCNN3/PIK3R1/NRAS/PIK3CA	11
KEGG	hsa00052	Galactose metabolism	6/1069	31/8135	0.2151	0.3764	0.242	HK3/AKR1B10/PFKM/GLA/AKR1B1/PGM1	6
KEGG	hsa05010	Alzheimer disease	56/1069	384/8135	0.2157	0.3764	0.242	LPL/ATF4/FZD2/DDIT3/COX7A1/FZD1/IRS1/XBP1/PSMA5/PSMC5/SLC39A14/PLCB2/PLCB1/TNF/MAPK10/PSMC3/NDUFV1/CALM1/NDUFS7/SLC39A8/NFKB1/MAPK1/LRP5/NDUFB7/PSEN1/ADAM10/RB1CC1/NDUFS5/WNT5A/CDK5/EIF2AK2/KLC1/TUBB/PIK3R1/CSNK2A2/PSMD8/BID/SLC25A6/FAS/NDUFC1/NRAS/PIK3CA/ULK1/PSEN2/WNT11/KIF5C/PSMC2/UQCRFS1/NDUFB5/PPIF/NDUFS6/PSMB2/NDUFAB1/FADD/COX6A2/CYBB	56
KEGG	hsa05203	Viral carcinogenesis	31/1069	204/8135	0.2162	0.3764	0.242	GSN/ATF4/HLA-F/CDKN1A/GRB2/CREB3L2/BAK1/JUN/HDAC1/CCNA2/SYK/CCR5/TRAF1/TRAF3/ACTN4/KAT2A/RAC1/NFKB1/MAPK1/HLA-G/HLA-A/LYN/YWHAB/EIF2AK2/PIK3R1/USP7/CDK4/CDK2/NRAS/PIK3CA/RB1	31
KEGG	hsa04927	Cortisol synthesis and secretion	11/1069	65/8135	0.2285	0.3957	0.2545	AGTR1/ATF4/CREB3L2/ADCY7/LDLR/PLCB2/PLCB1/PDE8B/ADCY6/AGT/NR4A1	11
KEGG	hsa04137	Mitophagy - animal	12/1069	72/8135	0.2311	0.398	0.256	GABARAPL1/ATF4/FOXO3/JUN/PINK1/MAPK10/SQSTM1/CSNK2A2/UBC/NRAS/ULK1/MAP1LC3B	12
KEGG	hsa04141	Protein processing in endoplasmic reticulum	26/1069	171/8135	0.2398	0.4109	0.2642	CRYAB/ATF4/BAG1/DDIT3/HSPA6/BAK1/UBXN1/XBP1/DNAJB1/RAD23A/PPP1R15A/SEL1L/UBE2G2/MAPK10/SEC24D/LMAN1/SSR4/WFS1/EIF2AK2/UBE2D2/UBE2G1/HSP90AB1/UBE2J1/HSPA5/PDIA3/RPN2	26
KEGG	hsa04550	Signaling pathways regulating pluripotency of stem cells	22/1069	143/8135	0.2443	0.4165	0.2678	MAPK13/FZD2/GRB2/TCF7/ID1/FZD1/ZFHX3/BMP4/KLF4/INHBB/MYC/MAPK1/SMAD3/WNT5A/LIFR/PIK3R1/PCGF2/NRAS/PIK3CA/ACVR2B/FGFR2/WNT11	22
KEGG	hsa04350	TGF-beta signaling pathway	15/1069	94/8135	0.2481	0.4208	0.2706	ID1/TGIF1/TNF/BMP4/INHBB/MYC/MAPK1/SMAD3/LTBP1/BMP5/ACVR2B/E2F5/SMURF2/IFNG/TFDP1	15
KEGG	hsa03410	Base excision repair	6/1069	33/8135	0.2607	0.4399	0.2829	PCNA/PARP1/POLD2/LIG1/PARP4/FEN1	6
KEGG	hsa00670	One carbon pool by folate	4/1069	20/8135	0.2636	0.4426	0.2846	ALDH1L1/TYMS/MTHFD2/SHMT2	4
KEGG	hsa04915	Estrogen signaling pathway	21/1069	138/8135	0.2675	0.4468	0.2873	EGFR/TGFA/ATF4/GRB2/HSPA6/FKBP5/CREB3L2/JUN/ADCY7/PLCB2/PLCB1/FKBP4/CALM1/MAPK1/ADCY6/PIK3R1/HBEGF/HSP90AB1/NRAS/PIK3CA/MMP9	21
KEGG	hsa04114	Oocyte meiosis	20/1069	131/8135	0.269	0.447	0.2875	PTTG1/MAPK13/CCNB1/RPS6KA1/ADCY7/AR/CCNB2/CALM1/MAPK1/PPP1CA/PLK1/YWHAB/RPS6KA2/ADCY6/CDK2/MAD2L1/PKMYT1/PPP2R5C/PPP1CC/SLK	20
KEGG	hsa04973	Carbohydrate digestion and absorption	8/1069	47/8135	0.2714	0.4488	0.2886	HK3/PRKCB/PLCB2/PLCB1/ATP1A1/PIK3R1/PIK3CA/SLC37A4	8
KEGG	hsa04918	Thyroid hormone synthesis	12/1069	75/8135	0.2767	0.4552	0.2927	ATF4/GPX3/PRKCB/CREB3L2/ADCY7/PLCB2/PLCB1/PAX8/ATP1A1/ADCY6/TPO/HSPA5	12
KEGG	hsa00280	Valine, leucine and isoleucine degradation	8/1069	48/8135	0.2915	0.4771	0.3068	ALDH6A1/HADH/ACADS/AOX1/ECHS1/BCKDHA/BCAT2/ACAT2	8
KEGG	hsa05031	Amphetamine addiction	11/1069	69/8135	0.2931	0.4774	0.307	MAOA/ATF4/PRKCB/CREB3L2/JUN/HDAC1/FOSB/SLC6A3/CALM1/PPP1CA/PPP1CC	11
KEGG	hsa04071	Sphingolipid signaling pathway	18/1069	119/8135	0.297	0.4813	0.3096	RAC2/MAPK13/PRKCB/PLCB2/PLCB1/TNF/MAPK10/FCER1G/ADORA1/RAC1/NFKB1/MAPK1/PIK3R1/BID/NRAS/PIK3CA/BDKRB2/PPP2R5C	18
KEGG	hsa04623	Cytosolic DNA-sensing pathway	10/1069	63/8135	0.3111	0.498	0.3202	CCL5/AIM2/POLR2E/NFKB1/IKBKE/CXCL10/IL18/CASP1/POLR2H/POLR3C	10
KEGG	hsa00520	Amino sugar and nucleotide sugar metabolism	8/1069	49/8135	0.3118	0.498	0.3202	HK3/GNE/UAP1/CYB5R1/HEXA/CYB5R3/PGM1/PMM1	8
KEGG	hsa05030	Cocaine addiction	8/1069	49/8135	0.3118	0.498	0.3202	MAOA/ATF4/CREB3L2/JUN/FOSB/SLC6A3/NFKB1/CDK5	8
KEGG	hsa01232	Nucleotide metabolism	13/1069	85/8135	0.3225	0.5126	0.3296	TYMS/TK1/TYMP/AMPD3/IMPDH2/NT5E/IMPDH1/AMPD1/DCK/ENTPD1/HDDC2/APRT/HPRT1	13
KEGG	hsa04922	Glucagon signaling pathway	16/1069	107/8135	0.3289	0.5203	0.3346	PCK1/FOXO1/ATF4/CREB3L2/PDE3B/PLCB2/PLCB1/PFKFB1/CALM1/ACACB/PFKM/LDHB/PHKA1/ACACA/PHKG1/PDHA1	16
KEGG	hsa04970	Salivary secretion	14/1069	93/8135	0.3351	0.5275	0.3392	PRKCB/ADCY7/KCNN4/PLCB2/PLCB1/VAMP2/CD38/CALM1/ATP1A1/LPO/ADCY6/BST1/PRKG1/LYZ	14
KEGG	hsa00430	Taurine and hypotaurine metabolism	3/1069	16/8135	0.3526	0.5521	0.3551	CDO1/GGT5/FMO2	3
KEGG	hsa04260	Cardiac muscle contraction	13/1069	87/8135	0.3541	0.5521	0.3551	TPM2/COX7A1/TPM4/CACNB3/ACTC1/ATP1A1/MYL2/MYH7/MYL3/UQCRFS1/CACNA2D2/CASQ2/COX6A2	13
KEGG	hsa03430	Mismatch repair	4/1069	23/8135	0.3577	0.5552	0.357	PCNA/POLD2/LIG1/RPA1	4
KEGG	hsa05207	Chemical carcinogenesis - receptor activation	30/1069	212/8135	0.3597	0.5556	0.3573	EGFR/RPS6KA1/ATF4/VDR/PRKCB/GRB2/CREB3L2/JUN/ARRB2/ADCY7/AR/TNFSF11/KLF4/JAG1/MYC/NFKB1/MAPK1/IKBKE/RPS6KA2/ADCY6/PIK3R1/HSP90AB1/EPHX1/EIF4EBP1/CDC6/NRAS/PIK3CA/RB1/GSTM3/GSTO1	30
KEGG	hsa04330	Notch signaling pathway	9/1069	59/8135	0.3701	0.5663	0.3642	HDAC1/HES1/JAG1/KAT2A/PSEN1/TLE2/TLE1/TLE4/PSEN2	9
KEGG	hsa04540	Gap junction	13/1069	88/8135	0.3701	0.5663	0.3642	EGFR/PRKCB/GRB2/ADCY7/PLCB2/PLCB1/MAPK1/ADCY6/TUBB/MAPK7/GJA1/NRAS/PRKG1	13
KEGG	hsa03040	Spliceosome	21/1069	147/8135	0.3752	0.5704	0.3668	HNRNPA1/SF3B2/HSPA6/SNRPD2/SNRPA/PRPF3/SF3A3/SART1/SRSF4/BUD31/SNRPD1/DHX38/SRSF6/PUF60/SNRNP40/PQBP1/PRPF6/SNRNP70/DDX42/U2AF2/PRPF19	21
KEGG	hsa04974	Protein digestion and absorption	15/1069	103/8135	0.3762	0.5704	0.3668	COL1A1/COL3A1/COL1A2/SLC7A7/COL8A1/COL5A2/SLC7A8/KCNN4/SLC1A5/DPP4/CPB1/ATP1A1/CELA2B/SLC3A2/CPA1	15
KEGG	hsa00410	beta-Alanine metabolism	5/1069	31/8135	0.3863	0.5829	0.3749	AOC3/ALDH6A1/ACADS/ECHS1/AOC2	5
KEGG	hsa00450	Selenocompound metabolism	3/1069	17/8135	0.3906	0.5841	0.3756	PAPSS2/CTH/PAPSS1	3
KEGG	hsa00910	Nitrogen metabolism	3/1069	17/8135	0.3906	0.5841	0.3756	CA4/GLUL/CA12	3
KEGG	hsa04070	Phosphatidylinositol signaling system	14/1069	97/8135	0.3966	0.5905	0.3797	INPP5D/PRKCB/PLCG2/PLCB2/PLCB1/CALM1/ITPKC/PI4K2A/IMPA2/SYNJ2/PIK3R1/PIK3CA/ITPK1/MTMR1	14
KEGG	hsa05231	Choline metabolism in cancer	14/1069	98/8135	0.4122	0.6077	0.3908	RAC2/EGFR/WASF3/PRKCB/GRB2/JUN/MAPK10/RAC1/MAPK1/PIK3R1/EIF4EBP1/NRAS/PIK3CA/LYPLA1	14
KEGG	hsa04014	Ras signaling pathway	32/1069	232/8135	0.4123	0.6077	0.3908	RAC2/EGFR/TGFA/PRKCB/GRB2/PLCG2/PAK1/RASGRP1/LAT/MAPK10/CALM1/RAC1/NFKB1/MAPK1/VEGFC/PIK3R1/FOXO4/ZAP70/EFNA1/ABL2/GNG11/ARF6/RALA/PAK2/NRAS/PIK3CA/FGFR2/VEGFB/EFNA5/GNG5/BRAP/ANGPT1	32
KEGG	hsa04215	Apoptosis - multiple species	5/1069	32/8135	0.4138	0.6077	0.3908	BAK1/MAPK10/BIRC3/BID/FADD	5
KEGG	hsa05032	Morphine addiction	13/1069	91/8135	0.4186	0.6121	0.3936	PRKCB/PDE3B/GRK5/ARRB2/ADCY7/ADORA1/PDE8B/ADCY6/PDE2A/GNG11/PDE1B/PDE1A/GNG5	13
KEGG	hsa03420	Nucleotide excision repair	7/1069	47/8135	0.4238	0.6169	0.3967	PCNA/RAD23A/POLD2/LIG1/DDB2/RPA1/ERCC1	7
KEGG	hsa01200	Carbon metabolism	16/1069	115/8135	0.444	0.6435	0.4139	ALDH6A1/HK3/ME2/TKT/ACADS/PC/IDH2/ECHS1/PHGDH/PFKM/ADH5/IDH3B/SHMT2/ESD/ACAT2/PDHA1	16
KEGG	hsa00310	Lysine degradation	9/1069	63/8135	0.449	0.6477	0.4165	EZH1/HADH/ECHS1/AASS/SETD1A/EHMT2/ACAT2/SETD2/PLOD2	9
KEGG	hsa05014	Amyotrophic lateral sclerosis	49/1069	364/8135	0.4508	0.6477	0.4165	MAPK13/HNRNPA1/ATF4/GPX3/DDIT3/ANG/COX7A1/PINK1/XBP1/PSMA5/PSMC5/RAB8A/TNF/SQSTM1/PSMC3/TNFRSF1B/NDUFV1/NUP210/NDUFS7/RAC1/NDUFB7/RB1CC1/NDUFS5/SOD1/DCTN3/KLC1/PFN1/TUBB/CASP1/DAXX/PSMD8/BID/HSPA5/FIG4/POM121/NDUFC1/ULK1/NUP62/KIF5C/PSMC2/MAP1LC3B/UQCRFS1/NDUFB5/MAP2K6/NDUFS6/PSMB2/SPG11/NDUFAB1/COX6A2	49
KEGG	hsa04024	cAMP signaling pathway	30/1069	221/8135	0.4539	0.6492	0.4175	RAC2/LIPE/MYL9/VAV1/PAK1/CREB3L2/PTGER3/JUN/NPR1/PDE3B/RAPGEF3/ADCY7/MAPK10/PLN/FXYD1/CALM1/ADORA1/RAC1/NFKB1/MAPK1/PPP1CA/ATP1A1/ADCY6/PIK3R1/SOX9/PIK3CA/OXT/VIPR2/F2R/PPP1CC	30
KEGG	hsa00531	Glycosaminoglycan degradation	3/1069	19/8135	0.4644	0.6585	0.4235	GNS/ARSB/HEXA	3
KEGG	hsa01210	2-Oxocarboxylic acid metabolism	3/1069	19/8135	0.4644	0.6585	0.4235	IDH2/BCAT2/IDH3B	3
KEGG	hsa04728	Dopaminergic synapse	18/1069	132/8135	0.4717	0.6641	0.427	MAOA/MAPK13/ATF4/PRKCB/CREB3L2/ARRB2/PLCB2/PLCB1/MAPK10/SLC6A3/COMT/CALM1/PPP1CA/GNG11/KIF5C/PPP2R5C/GNG5/PPP1CC	18
KEGG	hsa05016	Huntington disease	41/1069	306/8135	0.4723	0.6641	0.427	GPX3/PPARG/CREB3L2/COX7A1/HDAC1/PSMA5/PSMC5/PLCB2/PLCB1/MAPK10/PSMC3/NDUFV1/POLR2E/NDUFS7/POLR2I/NDUFB7/RB1CC1/CLTCL1/NDUFS5/SOD1/DCTN3/KLC1/TUBB/CLTB/POLR2H/HIP1/PSMD8/SLC25A6/NDUFC1/ULK1/POLR2B/KIF5C/PSMC2/UQCRFS1/NDUFB5/PPIF/NDUFS6/POLR2J/PSMB2/NDUFAB1/COX6A2	41
KEGG	hsa01040	Biosynthesis of unsaturated fatty acids	4/1069	27/8135	0.4821	0.6737	0.4333	SCD/ACOT7/ELOVL5/TECR	4
KEGG	hsa04723	Retrograde endocannabinoid signaling	20/1069	148/8135	0.4833	0.6737	0.4333	MAPK13/PRKCB/CNR1/ADCY7/PLCB2/PLCB1/MAPK10/NDUFV1/NDUFS7/MAPK1/NDUFB7/MGLL/NDUFS5/ADCY6/GNG11/NDUFC1/NDUFB5/GNG5/NDUFS6/NDUFAB1	20
KEGG	hsa00480	Glutathione metabolism	8/1069	58/8135	0.4997	0.6928	0.4455	GPX3/PRDX6/IDH2/GPX4/GGT5/GSTM3/GSTO1/GCLM	8
KEGG	hsa04390	Hippo signaling pathway	21/1069	157/8135	0.5011	0.6928	0.4455	TCF7L2/FZD2/ITGB2/TCF7/ID1/FZD1/AMOT/BMP4/MYC/SMAD3/PPP1CA/PARD3/WNT5A/BMP5/YWHAB/BIRC3/TEAD4/DLG5/WNT11/PPP1CC/LEF1	21
KEGG	hsa00650	Butanoate metabolism	4/1069	28/8135	0.5118	0.7045	0.4531	HADH/ACADS/ECHS1/ACAT2	4
KEGG	hsa05017	Spinocerebellar ataxia	19/1069	143/8135	0.5171	0.7089	0.4559	PRKCB/KAT5/XBP1/PSMA5/PSMC5/PLCB2/PLCB1/MAPK10/PSMC3/RB1CC1/PIK3R1/VLDLR/PSMD8/SLC25A6/PIK3CA/ULK1/PSMC2/PPIF/PSMB2	19
KEGG	hsa04217	Necroptosis	21/1069	159/8135	0.526	0.7181	0.4618	IFNAR2/STAT1/PARP1/TNF/MAPK10/SQSTM1/TNFSF10/GLUL/STAT4/BIRC3/EIF2AK2/CASP1/HSP90AB1/BID/SLC25A6/FAS/IFNG/IFNGR2/NLRP3/FADD/CYBB	21
KEGG	hsa04730	Long-term depression	8/1069	60/8135	0.5401	0.7343	0.4722	PRKCB/PLCB2/PLCB1/MAPK1/GNAZ/LYN/NRAS/PRKG1	8
KEGG	hsa00250	Alanine, aspartate and glutamate metabolism	5/1069	37/8135	0.5463	0.7366	0.4737	ASNS/ASS1/GLUL/ALDH4A1/ASPA	5
KEGG	hsa01250	Biosynthesis of nucleotide sugars	5/1069	37/8135	0.5463	0.7366	0.4737	HK3/GNE/UAP1/PGM1/PMM1	5
KEGG	hsa00900	Terpenoid backbone biosynthesis	3/1069	22/8135	0.5668	0.7575	0.4872	FDPS/MVD/ACAT2	3
KEGG	hsa04714	Thermogenesis	30/1069	232/8135	0.5684	0.7575	0.4872	MAPK13/RPS6KA1/PLIN1/LIPE/PPARG/GRB2/CNR1/CREB3L2/COX7A1/NPR1/ADCY7/PNPLA2/NDUFV1/NDUFAF1/NDUFS7/NDUFB7/MGLL/NDUFS5/ACSL1/RPS6KA2/ADCY6/SMARCD3/NDUFC1/NRAS/UQCRFS1/PRKG1/NDUFB5/NDUFS6/NDUFAB1/COX6A2	30
KEGG	hsa00630	Glyoxylate and dicarboxylate metabolism	4/1069	30/8135	0.5687	0.7575	0.4872	GLUL/SHMT2/ACAT2/GRHPR	4
KEGG	hsa04622	RIG-I-like receptor signaling pathway	9/1069	70/8135	0.5818	0.7719	0.4964	MAPK13/TNF/MAPK10/TRAF3/NFKB1/IKBKE/CXCL10/TBKBP1/FADD	9
KEGG	hsa04911	Insulin secretion	11/1069	86/8135	0.587	0.7756	0.4988	ATF4/PRKCB/CREB3L2/ADCY7/KCNN4/PLCB2/PLCB1/VAMP2/KCNN3/ATP1A1/ADCY6	11
KEGG	hsa04972	Pancreatic secretion	13/1069	102/8135	0.592	0.7779	0.5002	PRKCB/ADCY7/PLCB2/PLCB1/RAB8A/CD38/RAC1/CPB1/ATP1A1/ADCY6/BST1/CELA2B/CPA1	13
KEGG	hsa00513	Various types of N-glycan biosynthesis	5/1069	39/8135	0.5952	0.7779	0.5002	MAN2A1/MAN2A2/HEXA/RPN2/MGAT1	5
KEGG	hsa04614	Renin-angiotensin system	3/1069	23/8135	0.5982	0.7779	0.5002	AGTR1/ATP6AP2/AGT	3
KEGG	hsa04964	Proximal tubule bicarbonate reclamation	3/1069	23/8135	0.5982	0.7779	0.5002	PCK1/CA4/ATP1A1	3
KEGG	hsa04120	Ubiquitin mediated proteolysis	18/1069	142/8135	0.6037	0.7807	0.5021	CBLB/UBE2L6/UBE2C/UBE2G2/DDB2/BIRC3/UBE2E1/UBE2D2/UBE2A/UBE2G1/UBE2J1/SOCS3/HUWE1/UBC/SMURF2/PRPF19/UBA3/MID1	18
KEGG	hsa00604	Glycosphingolipid biosynthesis - ganglio series	2/1069	15/8135	0.6051	0.7807	0.5021	HEXA/ST3GAL2	2
KEGG	hsa00982	Drug metabolism - cytochrome P450	9/1069	72/8135	0.6171	0.7931	0.51	MAOA/ADH1A/ADH1B/ADH1C/AOX1/ADH5/GSTM3/FMO2/GSTO1	9
KEGG	hsa04130	SNARE interactions in vesicular transport	4/1069	33/8135	0.6466	0.8278	0.5324	VAMP8/VAMP5/VAMP2/SNAP23	4
KEGG	hsa04146	Peroxisome	10/1069	82/8135	0.6499	0.8288	0.533	IDH2/CRAT/ECH1/PEX19/PEX11A/ACSL1/SOD1/SLC27A2/PRDX1/CROT	10
KEGG	hsa00240	Pyrimidine metabolism	7/1069	58/8135	0.6544	0.8313	0.5346	TYMS/TK1/TYMP/NT5E/DCK/ENTPD1/HDDC2	7
KEGG	hsa05110	Vibrio cholerae infection	6/1069	50/8135	0.6577	0.8323	0.5352	PLCG2/TJP2/KDELR3/TCIRG1/KDELR1/ATP6V1A	6
KEGG	hsa00380	Tryptophan metabolism	5/1069	42/8135	0.6627	0.8354	0.5372	MAOA/HADH/AOX1/ECHS1/ACAT2	5
KEGG	hsa00040	Pentose and glucuronate interconversions	4/1069	34/8135	0.6704	0.8419	0.5414	AKR1A1/AKR1B10/AKR1B1/XYLB	4
KEGG	hsa04950	Maturity onset diabetes of the young	3/1069	26/8135	0.683	0.8544	0.5494	HES1/HHEX/HNF4A	3
KEGG	hsa04140	Autophagy - animal	17/1069	141/8135	0.687	0.8561	0.5506	GABARAPL1/VAMP8/DDIT4/IRS1/CTSL/RAB8A/MAPK10/SQSTM1/MAPK1/RB1CC1/PIK3R1/LAMP2/NRAS/PIK3CA/ULK1/STK11/MAP1LC3B	17
KEGG	hsa04962	Vasopressin-regulated water reabsorption	5/1069	44/8135	0.7034	0.8733	0.5616	ARHGDIB/CREB3L2/VAMP2/AQP3/ADCY6	5
KEGG	hsa00980	Metabolism of xenobiotics by cytochrome P450	9/1069	78/8135	0.7128	0.8773	0.5642	ADH1A/ADH1B/ADH1C/ADH5/EPHX1/GSTM3/CBR1/CYP2A13/GSTO1	9
KEGG	hsa00500	Starch and sucrose metabolism	4/1069	36/8135	0.7147	0.8773	0.5642	HK3/GBE1/GYG2/PGM1	4
KEGG	hsa00760	Nicotinate and nicotinamide metabolism	4/1069	36/8135	0.7147	0.8773	0.5642	AOX1/CD38/NT5E/BST1	4
KEGG	hsa04725	Cholinergic synapse	13/1069	113/8135	0.7386	0.9034	0.581	ATF4/PRKCB/CREB3L2/ADCY7/PLCB2/PLCB1/MAPK1/ADCY6/PIK3R1/GNG11/NRAS/PIK3CA/GNG5	13
KEGG	hsa03015	mRNA surveillance pathway	11/1069	97/8135	0.7451	0.9045	0.5817	CASC3/CLP1/UPF3A/PPP1CA/GSPT1/CSTF3/PAPOLA/CSTF1/PPP2R5C/RNPS1/PPP1CC	11
KEGG	hsa04713	Circadian entrainment	11/1069	97/8135	0.7451	0.9045	0.5817	PRKCB/ADCY7/PLCB2/PLCB1/CALM1/MAPK1/ADCY6/GNG11/PER2/PRKG1/GNG5	11
KEGG	hsa04392	Hippo signaling pathway - multiple species	3/1069	29/8135	0.7537	0.9116	0.5863	PAK1/RASSF2/TEAD4	3
KEGG	hsa00564	Glycerophospholipid metabolism	11/1069	98/8135	0.7572	0.9124	0.5867	GPD1/AGPAT2/LPIN1/PLA2G15/PCYT2/PNPLA6/PEMT/GPD1L/AGPAT1/LYPLA1/MBOAT7	11
KEGG	hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	2/1069	20/8135	0.7598	0.9124	0.5867	CHST7/UST	2
KEGG	hsa00030	Pentose phosphate pathway	3/1069	30/8135	0.7742	0.9263	0.5957	TKT/PFKM/PGM1	3
KEGG	hsa00770	Pantothenate and CoA biosynthesis	2/1069	21/8135	0.7836	0.9341	0.6007	VNN2/BCAT2	2
KEGG	hsa04971	Gastric acid secretion	8/1069	76/8135	0.7988	0.9421	0.6058	PRKCB/ADCY7/PLCB2/PLCB1/CALM1/MYLK/ATP1A1/ADCY6	8
KEGG	hsa00510	N-Glycan biosynthesis	5/1069	50/8135	0.8044	0.9421	0.6058	ST6GAL1/MAN2A1/MAN2A2/RPN2/MGAT1	5
KEGG	hsa04979	Cholesterol metabolism	5/1069	50/8135	0.8044	0.9421	0.6058	LPL/LDLR/PLTP/NPC1/LIPA	5
KEGG	hsa00220	Arginine biosynthesis	2/1069	22/8135	0.8053	0.9421	0.6058	ASS1/GLUL	2
KEGG	hsa00340	Histidine metabolism	2/1069	22/8135	0.8053	0.9421	0.6058	MAOA/ASPA	2
KEGG	hsa00830	Retinol metabolism	7/1069	68/8135	0.8075	0.9421	0.6058	ADH1A/ADH1B/ADH1C/DHRS3/AOX1/DGAT1/ADH5	7
KEGG	hsa00330	Arginine and proline metabolism	5/1069	51/8135	0.8183	0.9479	0.6096	MAOA/CKB/GATM/CKMT2/ALDH4A1	5
KEGG	hsa04913	Ovarian steroidogenesis	5/1069	51/8135	0.8183	0.9479	0.6096	ALOX5/AKR1C3/ADCY7/LDLR/ADCY6	5
KEGG	hsa04721	Synaptic vesicle cycle	8/1069	78/8135	0.8216	0.9484	0.6099	STXBP1/DNM1/VAMP2/SLC6A3/CLTCL1/TCIRG1/CLTB/ATP6V1A	8
KEGG	hsa03060	Protein export	2/1069	23/8135	0.825	0.949	0.6103	SPCS2/HSPA5	2
KEGG	hsa00590	Arachidonic acid metabolism	6/1069	61/8135	0.8303	0.9518	0.6121	GPX3/ALOX5/AKR1C3/PTGES/GGT5/CBR1	6
KEGG	hsa04975	Fat digestion and absorption	4/1069	43/8135	0.8348	0.9537	0.6133	AGPAT2/DGAT1/AGPAT1/ACAT2	4
KEGG	hsa03450	Non-homologous end-joining	1/1069	13/8135	0.8401	0.9563	0.615	FEN1	1
KEGG	hsa04977	Vitamin digestion and absorption	2/1069	24/8135	0.8429	0.9563	0.615	SLC5A6/TCN2	2
KEGG	hsa03460	Fanconi anemia pathway	5/1069	54/8135	0.8551	0.9668	0.6217	FANCC/REV3L/HES1/RPA1/ERCC1	5
KEGG	hsa02010	ABC transporters	4/1069	45/8135	0.8602	0.9669	0.6218	TAP1/ABCA8/ABCG1/ABCC10	4
KEGG	hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	1/1069	14/8135	0.8611	0.9669	0.6218	ST3GAL2	1
KEGG	hsa00730	Thiamine metabolism	1/1069	15/8135	0.8794	0.9841	0.6329	ALPL	1
KEGG	hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	2/1069	27/8135	0.8871	0.986	0.6341	ST3GAL4/ABO	2
KEGG	hsa04966	Collecting duct acid secretion	2/1069	27/8135	0.8871	0.986	0.6341	TCIRG1/ATP6V1A	2
KEGG	hsa04726	Serotonergic synapse	11/1069	115/8135	0.9048	1	0.6431	MAOA/PRKCB/ALOX5/RAPGEF3/PLCB2/PLCB1/MAPK1/DUSP1/GNG11/NRAS/GNG5	11
KEGG	hsa03018	RNA degradation	7/1069	79/8135	0.9092	1	0.6431	BTG2/BTG1/LSM1/PAN2/TOB2/PFKM/EXOSC7	7
KEGG	hsa00190	Oxidative phosphorylation	13/1069	134/8135	0.9107	1	0.6431	COX7A1/NDUFV1/NDUFS7/NDUFB7/NDUFS5/TCIRG1/NDUFC1/UQCRFS1/NDUFB5/ATP6V1A/NDUFS6/NDUFAB1/COX6A2	13
KEGG	hsa00983	Drug metabolism - other enzymes	7/1069	80/8135	0.9156	1	0.6431	TK1/TYMP/IMPDH2/IMPDH1/GSTM3/GSTO1/HPRT1	7
KEGG	hsa00600	Sphingolipid metabolism	4/1069	52/8135	0.9245	1	0.6431	GALC/ARSA/GLA/HEXA	4
KEGG	hsa04710	Circadian rhythm	2/1069	31/8135	0.9282	1	0.6431	NPAS2/PER2	2
KEGG	hsa04724	Glutamatergic synapse	10/1069	114/8135	0.9437	1	0.6431	PRKCB/ADCY7/PLCB2/PLCB1/GLUL/MAPK1/ADCY6/GNG11/HOMER3/GNG5	10
KEGG	hsa04727	GABAergic synapse	7/1069	89/8135	0.9577	1	0.6431	GABARAPL1/PRKCB/ADCY7/GLUL/ADCY6/GNG11/GNG5	7
KEGG	hsa05204	Chemical carcinogenesis - DNA adducts	5/1069	69/8135	0.9586	1	0.6431	EPHX1/GSTM3/CBR1/CYP2A13/GSTO1	5
KEGG	hsa03008	Ribosome biogenesis in eukaryotes	9/1069	109/8135	0.9591	1	0.6431	FBL/NHP2/POP5/POP4/IMP4/CSNK2A2/TBL3/EMG1/WDR43	9
KEGG	hsa00512	Mucin type O-glycan biosynthesis	2/1069	36/8135	0.9599	1	0.6431	GCNT1/ST3GAL2	2
KEGG	hsa00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	1/1069	24/8135	0.9662	1	0.6431	EXT1	1
KEGG	hsa05168	Herpes simplex virus 1 infection	52/1069	495/8135	0.9713	1	0.6431	CCL5/HLA-DRB4/HLA-DMA/TAP1/HLA-F/HLA-DMB/HLA-DOB/IFNAR2/ZNF473/MYD88/BAK1/STAT1/OAS1/HLA-DPB1/TAPBP/OAS2/HLA-DPA1/CFP/SYK/HLA-DOA/TNF/CD74/SRSF4/TRAF3/NFKB1/IKBKE/HLA-G/PPP1CA/EIF2B4/HLA-A/BIRC3/EIF2AK2/ZNF248/PIK3R1/POU2F1/ZNF205/DAXX/HLA-DRA/BID/SOCS3/EIF4EBP1/FAS/SRSF6/PIK3CA/TLR2/PDIA3/ZNF250/IFNG/IFNGR2/FADD/ZNF549/PPP1CC	52
KEGG	hsa01240	Biosynthesis of cofactors	13/1069	153/8135	0.9727	1	0.6431	NQO1/AKR1A1/DHRS3/MTHFD2/MOCS1/ALPL/BCAT2/SHMT2/GGH/PMM1/HPD/COQ2/GCLM	13
KEGG	hsa00563	Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	1/1069	26/8135	0.9745	1	0.6431	PIGQ	1
KEGG	hsa05206	MicroRNAs in cancer	30/1069	310/8135	0.9766	1	0.6431	EGFR/CDKN1A/PRKCB/GRB2/PLCG2/BAK1/MARCKS/DDIT4/IRS1/HDAC1/SPRY2/BCL2L2/MYC/NFKB1/MAPK1/PIM1/STMN1/CD44/HMOX1/PIK3R1/EFNA1/MAPK7/CDC25B/TNC/DNMT1/NRAS/PIK3CA/EFNA5/FSCN1/MMP9	30
KEGG	hsa04742	Taste transduction	6/1069	86/8135	0.9769	1	0.6431	PLCB2/PLCB1/ADCY6/SCNN1B/PDE1B/PDE1A	6
KEGG	hsa03440	Homologous recombination	2/1069	41/8135	0.9779	1	0.6431	POLD2/RPA1	2
KEGG	hsa05034	Alcoholism	16/1069	187/8135	0.9813	1	0.6431	MAOA/ATF4/GRB2/CREB3L2/HDAC1/FOSB/SLC6A3/CALM1/MAPK1/SLC29A1/PPP1CA/GNG11/NRAS/GNG5/PPP1CC/SLC29A2	16
KEGG	hsa04976	Bile secretion	6/1069	89/8135	0.9823	1	0.6431	AQP9/ADCY7/LDLR/ATP1A1/ADCY6/EPHX1	6
KEGG	hsa00860	Porphyrin metabolism	2/1069	43/8135	0.9826	1	0.6431	BLVRA/HMOX1	2
KEGG	hsa04744	Phototransduction	1/1069	29/8135	0.9833	1	0.6431	CALM1	1
KEGG	hsa04340	Hedgehog signaling pathway	3/1069	56/8135	0.9835	1	0.6431	ARRB2/GPR161/SMURF2	3
KEGG	hsa00053	Ascorbate and aldarate metabolism	1/1069	30/8135	0.9855	1	0.6431	AKR1A1	1
KEGG	hsa03022	Basal transcription factors	2/1069	45/8135	0.9864	1	0.6431	TAF11/TAF6	2
KEGG	hsa04136	Autophagy - other	1/1069	32/8135	0.9891	1	0.6431	GABARAPL1	1
KEGG	hsa00140	Steroid hormone biosynthesis	3/1069	61/8135	0.9905	1	0.6431	AKR1C3/SRD5A1/COMT	3
KEGG	hsa03013	Nucleocytoplasmic transport	7/1069	108/8135	0.9916	1	0.6431	CASC3/EEF1A2/NUP210/UPF3A/POM121/NUP62/RNPS1	7
KEGG	hsa00514	Other types of O-glycan biosynthesis	1/1069	47/8135	0.9987	1	0.6431	ST6GAL1	1
KEGG	hsa04080	Neuroactive ligand-receptor interaction	29/1069	353/8135	0.9988	1	0.6431	AGTR1/ADM/P2RY6/PTAFR/GZMA/VIPR1/CNR1/PTGER3/NMB/THRA/EDNRB/P2RX4/C3AR1/ADORA1/FPR3/P2RX5/PARD3/GAL/PTH1R/ADRA2A/FPR1/P2RY10/OXT/AGT/AVPR1A/BDKRB2/VIPR2/F2R/PTGER4	29
KEGG	hsa00565	Ether lipid metabolism	1/1069	49/8135	0.999	1	0.6431	PLA2G7	1
KEGG	hsa00970	Aminoacyl-tRNA biosynthesis	2/1069	66/8135	0.999	1	0.6431	FARSA/GATC	2
KEGG	hsa04740	Olfactory transduction	6/1069	440/8135	1	1	0.6431	ARRB2/CALM1/PDE2A/PDE1B/PDE1A/PRKG1	6