ONTOLOGY	ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	qvalue	geneID	Count
KEGG	hsa05415	Diabetic cardiomyopathy	47/794	203/8135	1.071e-08	3.429e-06	2.684e-06	NDUFA6/NDUFS4/NDUFC1/SP1/ATP2A3/NDUFB6/UQCRC2/NDUFA13/COX5B/NDUFA2/PDHB/NDUFA4/NDUFA8/NDUFB7/NDUFB8/SDHB/CYBB/COX6C/CD36/NFKB1/PLCB2/COX7A1/RAC2/NDUFB3/NDUFB5/PIK3CD/NDUFA12/PRKCA/NDUFB9/NDUFS3/CYC1/COL3A1/UQCRFS1/NDUFA11/MMP2/AGER/COX6B1/SDHD/NDUFA3/COX8A/PDHA1/NDUFS7/PRKCB/IRS1/COX7C/NDUFS5/NDUFB1	47
KEGG	hsa04932	Non-alcoholic fatty liver disease	38/794	155/8135	5.645e-08	9.032e-06	7.071e-06	NDUFA6/NDUFS4/NDUFC1/XBP1/NDUFB6/UQCRC2/NDUFA13/COX5B/NDUFA2/NDUFA4/NDUFA8/PPARG/NDUFB7/NDUFB8/SDHB/COX6C/NFKB1/COX7A1/NDUFB3/NDUFB5/PIK3CD/NDUFA12/NDUFB9/NDUFS3/CYC1/CEBPA/UQCRFS1/NDUFA11/COX6B1/SDHD/MLXIPL/NDUFA3/COX8A/NDUFS7/IRS1/COX7C/NDUFS5/NDUFB1	38
KEGG	hsa05012	Parkinson disease	54/794	266/8135	1.066e-07	1.137e-05	8.9e-06	UCHL1/NDUFA6/NDUFS4/TRAP1/NDUFC1/SLC39A14/XBP1/MAPT/NDUFB6/PSMD8/UBE2J1/UQCRC2/NDUFA13/COX5B/NDUFA2/ATF6/ADORA2A/NDUFA4/NDUFA8/NDUFB7/PSMD4/HSPA5/NDUFB8/SDHB/DAXX/COX6C/TUBB2A/GNAI1/UBA7/COX7A1/NDUFB3/PSMB7/PARK7/NDUFB5/NDUFA12/NDUFB9/NDUFS3/CYC1/PINK1/PSMB5/UQCRFS1/NDUFA11/ITPR3/PSMD1/COX6B1/SDHD/NDUFA3/COX8A/NDUFS7/COX7C/PSMB3/NDUFS5/NDUFB1/SLC39A13	54
KEGG	hsa00190	Oxidative phosphorylation	33/794	134/8135	3.789e-07	3.031e-05	2.373e-05	NDUFA6/NDUFS4/NDUFC1/NDUFB6/UQCRC2/NDUFA13/COX5B/NDUFA2/NDUFA4/NDUFA8/NDUFB7/NDUFB8/SDHB/COX6C/COX17/COX7A1/NDUFB3/PPA2/NDUFB5/NDUFA12/NDUFB9/NDUFS3/CYC1/UQCRFS1/NDUFA11/COX6B1/SDHD/NDUFA3/COX8A/NDUFS7/COX7C/NDUFS5/NDUFB1	33
KEGG	hsa05208	Chemical carcinogenesis - reactive oxygen species	44/794	223/8135	3.652e-06	0.0002002	0.0001567	PTPN1/NDUFA6/NDUFS4/NDUFC1/NQO1/NDUFB6/UQCRC2/NDUFA13/COX5B/NDUFA2/NDUFA4/NDUFA8/IKBKG/NDUFB7/MGST3/NFKBIA/NDUFB8/SDHB/COX6C/AKR1C3/NFKB1/COX7A1/NDUFB3/NDUFB5/PIK3CD/NDUFA12/NDUFB9/NDUFS3/CYC1/UQCRFS1/NDUFA11/MGST2/COX6B1/SDHD/AKR1C2/NDUFA3/MAPK3/COX8A/NDUFS7/PRKD2/COX7C/NDUFS5/NDUFB1/GRB2	44
KEGG	hsa05169	Epstein-Barr virus infection	41/794	202/8135	3.753e-06	0.0002002	0.0001567	TAP1/CCND3/CD3D/CD247/E2F2/RUNX3/HLA-G/STAT1/IFNAR2/PLCG2/ENTPD1/HLA-DOB/SYK/NFKBIE/PSMD8/HLA-A/CD3G/CD19/HLA-DOA/IKBKG/ITGAL/PSMD4/NFKBIA/CXCL10/NFKB1/LYN/HES1/PIK3CD/IFNAR1/CD3E/IFNA16/IKBKE/PSMD1/HLA-DQA1/CD40/HLA-DMB/HLA-DPB1/IRF7/CDK6/IRF3/HLA-DRB4	41
KEGG	hsa04658	Th1 and Th2 cell differentiation	24/794	92/8135	5.039e-06	0.0002304	0.0001804	CD3D/CD247/IL4R/RUNX3/STAT1/IL2RG/HLA-DOB/NFKBIE/CD3G/HLA-DOA/JAK2/IKBKG/NFKBIA/TBX21/LAT/IL2RB/NFKB1/CD3E/HLA-DQA1/HLA-DMB/HLA-DPB1/MAPK3/LCK/HLA-DRB4	24
KEGG	hsa04659	Th17 cell differentiation	26/794	108/8135	1.012e-05	0.0004046	0.0003168	CD3D/CD247/IL4R/STAT1/IL2RG/HLA-DOB/IRF4/NFKBIE/CD3G/HLA-DOA/JAK2/IKBKG/NFKBIA/TBX21/LAT/IL27RA/IL2RB/NFKB1/CD3E/RARA/HLA-DQA1/HLA-DMB/HLA-DPB1/MAPK3/LCK/HLA-DRB4	26
KEGG	hsa05016	Huntington disease	53/794	306/8135	2.085e-05	0.0007415	0.0005805	NDUFA6/NDUFS4/NDUFC1/SP1/NDUFB6/PSMD8/POLR2I/POLR2F/UQCRC2/STX1A/GRIA2/NDUFA13/COX5B/DCTN3/NDUFA2/GPX5/NDUFA4/DCTN2/NDUFA8/POLR2C/PPARG/NDUFB7/PSMD4/NDUFB8/SDHB/COX6C/TUBB2A/PLCB2/COX7A1/NDUFB3/PSMB7/NDUFB5/DLG4/NDUFA12/POLR2H/NDUFB9/POLR2L/NDUFS3/CYC1/PSMB5/UQCRFS1/NDUFA11/PSMD1/COX6B1/SDHD/NDUFA3/COX8A/POLR2J3/NDUFS7/COX7C/PSMB3/NDUFS5/NDUFB1	53
KEGG	hsa05020	Prion disease	48/794	273/8135	3.445e-05	0.001027	0.0008044	NDUFA6/NDUFS4/NDUFC1/NDUFB6/PSMD8/UQCRC2/NDUFA13/COX5B/NDUFA2/NDUFA4/CCL5/NDUFA8/NDUFB7/PSMD4/HSPA5/NDUFB8/SDHB/CYBB/COX6C/TUBB2A/COX7A1/RAC2/NDUFB3/PSMB7/NDUFB5/PIK3CD/NDUFA12/NDUFB9/FYN/NDUFS3/CYC1/PSMB5/UQCRFS1/NDUFA11/ITPR3/PSMD1/C6/COX6B1/SDHD/NDUFA3/MAPK3/COX8A/NDUFS7/COX7C/PSMB3/C1QA/NDUFS5/NDUFB1	48
KEGG	hsa05340	Primary immunodeficiency	13/794	38/8135	3.532e-05	0.001027	0.0008044	TAP1/CD3D/IL7R/IL2RG/CD19/CD8A/IKBKG/CD3E/CIITA/CD79A/CD40/ADA/LCK	13
KEGG	hsa04623	Cytosolic DNA-sensing pathway	17/794	63/8135	7.532e-05	0.002009	0.001572	ZBP1/AIM2/POLR2F/CCL5/IKBKG/NFKBIA/POLR3K/CXCL10/NFKB1/RIPK3/POLR2H/POLR2L/IFNA16/IKBKE/TREX1/IRF7/IRF3	17
KEGG	hsa05022	Pathways of neurodegeneration - multiple diseases	72/794	476/8135	8.556e-05	0.002106	0.001649	UCHL1/NDUFA6/NDUFS4/TRAP1/NDUFC1/XBP1/ATP2A3/MAPT/NDUFB6/PSMD8/UBE2J1/UQCRC2/ATXN1/STX1A/GRIA2/NDUFA13/MAP1LC3B/COX5B/DCTN3/WNT11/NDUFA2/ATF6/GPX5/NDUFA4/DCTN2/NDUFA8/NDUFB7/TNFRSF1B/PSMD4/HSPA5/NDUFB8/SDHB/FZD5/CYBB/DAXX/COX6C/TUBB2A/NFKB1/PLCB2/UBA7/COX7A1/WNT1/NDUFB3/PSMB7/PARK7/NDUFB5/DLG4/NDUFA12/PRKCA/NDUFB9/NDUFS3/DKK4/CYC1/PINK1/PSMB5/UQCRFS1/NDUFA11/ITPR3/AGER/PSMD1/COX6B1/SDHD/NDUFA3/FZD2/MAPK3/COX8A/NDUFS7/PRKCB/COX7C/PSMB3/NDUFS5/NDUFB1	72
KEGG	hsa04510	Focal adhesion	37/794	201/8135	0.0001024	0.00234	0.001832	CCND3/BIRC3/ITGB7/DIAPH1/COL4A1/VEGFB/THBS3/LAMB1/PPP1R12C/ITGA5/MYLK4/THBS2/LAMA2/RAP1B/RAC2/RELN/PGF/ITGA7/PIK3CD/VASP/PRKCA/FYN/LAMC2/COL6A3/RAP1A/ACTB/ITGB4/TLN1/ELK1/TLN2/FN1/MAPK3/PRKCB/COL4A2/COL6A6/MYL9/GRB2	37
KEGG	hsa04714	Thermogenesis	41/794	232/8135	0.0001135	0.002422	0.001896	NDUFA6/NDUFS4/NDUFC1/ADCY1/NDUFB6/UQCRC2/PNPLA2/NDUFAF2/NDUFA13/COX5B/NDUFA2/NDUFA4/NDUFA8/PPARG/NDUFB7/NDUFB8/SDHB/COX6C/COX17/COX7A1/NDUFB3/LIPE/NDUFB5/NDUFA12/NDUFB9/RPS6KA1/NDUFS3/CYC1/UQCRFS1/ACTB/NDUFA11/COX6B1/SDHD/NDUFA3/COX8A/NDUFS7/COX7C/NDUFS5/NDUFB1/NDUFAF1/GRB2	41
KEGG	hsa05010	Alzheimer disease	60/794	384/8135	0.0001367	0.002673	0.002092	NDUFA6/NDUFS4/NDUFC1/SLC39A14/XBP1/ATP2A3/MAPT/NDUFB6/PSMD8/UQCRC2/NDUFA13/COX5B/WNT11/NDUFA2/ATF6/NDUFA4/NDUFA8/IKBKG/NDUFB7/PSMD4/NDUFB8/SDHB/FZD5/CYBB/COX6C/TUBB2A/NAE1/NFKB1/PLCB2/COX7A1/WNT1/LPL/NDUFB3/PSMB7/NDUFB5/PIK3CD/NDUFA12/NDUFB9/NDUFS3/DKK4/CYC1/PSMB5/UQCRFS1/NDUFA11/ITPR3/AGER/PSMD1/COX6B1/SDHD/NDUFA3/FZD2/MAPK3/COX8A/NDUFS7/IRS1/COX7C/PSMB3/NDUFS5/NDUFB1/SLC39A13	60
KEGG	hsa05416	Viral myocarditis	16/794	60/8135	0.000142	0.002673	0.002092	HLA-G/EIF4G3/HLA-DOB/HLA-A/HLA-DOA/SGCB/ITGAL/LAMA2/RAC2/FYN/ACTB/HLA-DQA1/CD40/HLA-DMB/HLA-DPB1/HLA-DRB4	16
KEGG	hsa00071	Fatty acid degradation	13/794	43/8135	0.0001504	0.002674	0.002093	ECHS1/ACAA1/HADH/ADH1A/ACAA2/HADHB/ADH1C/ACAT1/ACADS/ACADL/ALDH7A1/ACADM/ADH1B	13
KEGG	hsa04640	Hematopoietic cell lineage	22/794	99/8135	0.0001716	0.002889	0.002262	CD3D/CD2/CD7/IL4R/IL7R/CD38/HLA-DOB/CD3G/ANPEP/CD19/HLA-DOA/ITGA5/CD8A/CD59/CSF1R/CD36/CD3E/HLA-DQA1/CD14/HLA-DMB/HLA-DPB1/HLA-DRB4	22
KEGG	hsa04723	Retrograde endocannabinoid signaling	29/794	148/8135	0.000187	0.002992	0.002342	NDUFA6/NDUFS4/NDUFC1/ADCY1/NDUFB6/GRIA2/NDUFA13/NDUFA2/GNG11/NDUFA4/NDUFA8/NDUFB7/NDUFB8/GNAI1/PLCB2/NDUFB3/NDUFB5/NDUFA12/PRKCA/NDUFB9/NDUFS3/NDUFA11/ITPR3/NDUFA3/MAPK3/NDUFS7/PRKCB/NDUFS5/NDUFB1	29
KEGG	hsa04662	B cell receptor signaling pathway	19/794	82/8135	0.0002651	0.00404	0.003163	INPP5D/PLCG2/SYK/NFKBIE/CD19/CD72/IKBKG/NFKBIA/NFKB1/RAC2/LYN/PIK3CD/CD79A/LILRB3/CD79B/MAPK3/PRKCB/PIK3AP1/GRB2	19
KEGG	hsa05145	Toxoplasmosis	23/794	112/8135	0.0004205	0.006116	0.004788	PIK3CG/BIRC3/STAT1/HLA-DOB/LAMB1/HLA-DOA/JAK2/IKBKG/NFKBIA/LAMA2/IL10RA/GNAI1/NFKB1/LAMC2/BIRC7/CIITA/LY96/HLA-DQA1/CD40/HLA-DMB/HLA-DPB1/MAPK3/HLA-DRB4	23
KEGG	hsa05014	Amyotrophic lateral sclerosis	55/794	364/8135	0.0006062	0.008434	0.006603	NDUFA6/NDUFS4/NDUFC1/PFN2/XBP1/NDUFB6/PSMD8/UQCRC2/GRIA2/NDUFA13/POM121L2/MAP1LC3B/COX5B/DCTN3/NDUFA2/ATF6/GPX5/NDUFA4/DCTN2/NDUFA8/CHCHD10/NDUFB7/TNFRSF1B/PSMD4/HSPA5/NDUFB8/SDHB/DAXX/COX6C/TUBB2A/COX7A1/NDUFB3/PSMB7/NDUFB5/NDUFA12/NDUFB9/NDUFS3/CYC1/PINK1/PSMB5/UQCRFS1/ACTB/NDUFA11/ITPR3/PSMD1/COX6B1/SDHD/NDUFA3/COX8A/NDUFS7/COX7C/PSMB3/NDUFS5/NDUFB1/NUP210	55
KEGG	hsa04611	Platelet activation	24/794	124/8135	0.0007854	0.01013	0.007933	PIK3CG/PLCG2/ADCY1/SYK/MYLK4/RAP1B/GNAI1/PLCB2/LYN/RASGRP1/PIK3CD/VASP/FYN/COL3A1/RAP1A/ACTB/SNAP23/ITPR3/TLN1/VAMP8/ARHGEF1/TLN2/MAPK3/PTGS1	24
KEGG	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	19/794	89/8135	0.0007916	0.01013	0.007933	CD3D/CD247/STAT1/NFKBIE/CD3G/BATF3/BATF/JAK2/IKBKG/NFKBIA/LAT/NFKB1/TICAM2/RASGRP1/PIK3CD/EML4/CD3E/MAPK3/LCK	19
KEGG	hsa03060	Protein export	8/794	23/8135	0.001027	0.01222	0.009564	IMMP2L/SPCS2/SPCS3/SRPRB/SEC11C/HSPA5/SEC63/SEC61A1	8
KEGG	hsa05164	Influenza A	30/794	171/8135	0.001031	0.01222	0.009564	CCND3/STAT1/DNAJC3/IFNAR2/HLA-DOB/HLA-DOA/CCL5/JAK2/IKBKG/NFKBIA/CXCL10/NFKB1/PIK3CD/HNRNPUL1/PRKCA/IFNAR1/CIITA/ACTB/IFNA16/IKBKE/HLA-DQA1/HLA-DMB/HLA-DPB1/MAPK3/IRF7/PRKCB/CDK6/IRF3/HLA-DRB4/RNASEL	30
KEGG	hsa04670	Leukocyte transendothelial migration	22/794	114/8135	0.001331	0.01521	0.01191	EZR/ITK/PLCG2/SIPA1/ITGAL/CYBB/RAP1B/GNAI1/CLDN5/THY1/RAC2/PIK3CD/VASP/PRKCA/RAP1A/ACTB/MMP2/PRKCB/OCLN/MSN/CLDN14/MYL9	22
KEGG	hsa00620	Pyruvate metabolism	12/794	47/8135	0.00144	0.01589	0.01244	ADH1A/ACYP2/PDHB/ADH1C/ACAT1/ACSS2/GRHPR/LDHD/ALDH7A1/PDHA1/ACACA/ADH1B	12
KEGG	hsa00630	Glyoxylate and dicarboxylate metabolism	9/794	30/8135	0.001666	0.01776	0.0139	HYI/GCSH/ACAT1/ACSS2/GRHPR/SHMT2/AGXT/GLYCTK/HAO1	9
KEGG	hsa04062	Chemokine signaling pathway	32/794	192/8135	0.00172	0.01776	0.0139	PIK3CG/ITK/CXCL9/STAT1/PLCG2/ADCY1/CXCL13/PREX1/GNG11/CXCL6/CCL5/JAK2/IKBKG/XCL2/NFKBIA/CXCL10/RAP1B/GNAI1/NFKB1/PLCB2/RAC2/LYN/WAS/CXCL1/CCR7/PIK3CD/DOCK2/RAP1A/CCL13/MAPK3/PRKCB/GRB2	32
KEGG	hsa04620	Toll-like receptor signaling pathway	20/794	104/8135	0.00226	0.0226	0.0177	CXCL9/STAT1/IFNAR2/CCL5/IKBKG/NFKBIA/CXCL10/NFKB1/TICAM2/PIK3CD/IFNAR1/IFNA16/LY96/IKBKE/TOLLIP/CD40/CD14/MAPK3/IRF7/IRF3	20
KEGG	hsa05330	Allograft rejection	10/794	38/8135	0.002774	0.0269	0.02106	HLA-G/HLA-DOB/HLA-A/HLA-DOA/GZMB/HLA-DQA1/CD40/HLA-DMB/HLA-DPB1/HLA-DRB4	10
KEGG	hsa01200	Carbon metabolism	21/794	115/8135	0.00342	0.03219	0.0252	ECHS1/H6PD/SUCLA2/PDHB/GCSH/ACAT1/HIBCH/SDHB/ACSS2/ACADS/SHMT2/HK3/ADPGK/AGXT/IDH3B/GLYCTK/SDHD/SUCLG1/SDS/PDHA1/HAO1	21
KEGG	hsa00260	Glycine, serine and threonine metabolism	10/794	40/8135	0.004159	0.03803	0.02977	GCSH/CBS/GRHPR/SHMT2/ALDH7A1/AGXT/GLYCTK/CHDH/BHMT/SDS	10
KEGG	hsa04514	Cell adhesion molecules	25/794	149/8135	0.004807	0.04273	0.03345	ITGB7/CD2/CD6/HLA-G/HLA-DOB/HLA-A/GLG1/HLA-DOA/CD8A/ICAM3/ITGAL/CLDN5/SELL/CADM3/NLGN4Y/ALCAM/MAG/HLA-DQA1/CD226/CD40/HLA-DMB/HLA-DPB1/OCLN/CLDN14/HLA-DRB4	25
KEGG	hsa04064	NF-kappa B signaling pathway	19/794	104/8135	0.005194	0.04492	0.03517	BIRC3/PLCG2/SYK/TRAF1/LTA/IKBKG/NFKBIA/LTB/LAT/NFKB1/TICAM2/LYN/CXCL1/LY96/CD40/CCL13/CD14/PRKCB/LCK	19
KEGG	hsa00280	Valine, leucine and isoleucine degradation	11/794	48/8135	0.005542	0.04612	0.0361	HIBADH/ECHS1/ACAA1/HADH/ACAA2/HADHB/ACAT1/HIBCH/ACADS/ALDH7A1/ACADM	11
KEGG	hsa05417	Lipid and atherosclerosis	33/794	215/8135	0.00562	0.04612	0.0361	MMP3/HSP90B1/MMP1/XBP1/ATF6/CCL5/JAK2/IKBKG/PPARG/NFKBIA/HSPA5/CYBB/RAP1B/CD36/NFKB1/TICAM2/PLCB2/LYN/CXCL1/PIK3CD/PRKCA/RAP1A/IFNA16/LY96/IKBKE/AGER/VLDLR/CD40/CD14/ARHGEF1/MAPK3/IRF7/IRF3	33
KEGG	hsa04621	NOD-like receptor signaling pathway	29/794	184/8135	0.006286	0.05025	0.03934	BIRC3/PSTPIP1/GBP5/STAT1/AIM2/IFNAR2/GBP2/ATG16L1/MAP1LC3B/CCL5/IKBKG/NFKBIA/CYBB/CARD9/GABARAPL2/NFKB1/RIPK3/PLCB2/CARD8/CXCL1/IFNAR1/IFNA16/ITPR3/IKBKE/TRPM7/MAPK3/IRF7/IRF3/RNASEL	29
KEGG	hsa00512	Mucin type O-glycan biosynthesis	9/794	36/8135	0.006438	0.05025	0.03934	ST6GALNAC4/C1GALT1/C1GALT1C1/ST6GALNAC2/GALNT10/ST3GAL2/GALNT9/GALNT12/GALNT1	9
KEGG	hsa05140	Leishmaniasis	15/794	77/8135	0.006763	0.05151	0.04032	STAT1/HLA-DOB/HLA-DOA/JAK2/NFKBIA/CYBB/NFKB1/HLA-DQA1/ELK1/FCGR3B/HLA-DMB/HLA-DPB1/MAPK3/PRKCB/HLA-DRB4	15
KEGG	hsa05222	Small cell lung cancer	17/794	92/8135	0.007089	0.05151	0.04032	BIRC3/E2F2/COL4A1/LAMB1/TRAF1/IKBKG/NFKBIA/CKS1B/LAMA2/NFKB1/PIK3CD/LAMC2/BIRC7/TRAF4/FN1/CDK6/COL4A2	17
KEGG	hsa04940	Type I diabetes mellitus	10/794	43/8135	0.007199	0.05151	0.04032	HLA-G/HLA-DOB/HLA-A/HLA-DOA/LTA/GZMB/HLA-DQA1/HLA-DMB/HLA-DPB1/HLA-DRB4	10
KEGG	hsa05167	Kaposi sarcoma-associated herpesvirus infection	30/794	194/8135	0.007243	0.05151	0.04032	PIK3CG/E2F2/HLA-G/STAT1/IFNAR2/PLCG2/SYK/LEF1/HLA-A/PREX1/MICB/MAP1LC3B/GNG11/JAK2/IKBKG/NFKBIA/NFKB1/LYN/CXCL1/PIK3CD/IFNAR1/MAPKAPK2/CLEC2B/IFNA16/ITPR3/IKBKE/MAPK3/IRF7/CDK6/IRF3	30
KEGG	hsa04933	AGE-RAGE signaling pathway in diabetic complications	18/794	100/8135	0.007518	0.0523	0.04094	STAT1/DIAPH1/PLCG2/COL4A1/VEGFB/JAK2/CYBB/NFKB1/PLCB2/PIK3CD/PRKCA/COL3A1/MMP2/AGER/FN1/MAPK3/PRKCB/COL4A2	18
KEGG	hsa04650	Natural killer cell mediated cytotoxicity	22/794	131/8135	0.007786	0.05301	0.0415	CD247/HLA-G/IFNAR2/PLCG2/SH2D1A/SYK/HLA-A/MICB/ITGAL/LAT/RAC2/PIK3CD/PRKCA/IFNAR1/GZMB/FYN/IFNA16/FCGR3B/MAPK3/PRKCB/LCK/GRB2	22
KEGG	hsa05310	Asthma	8/794	31/8135	0.008192	0.05461	0.04276	FCER1A/HLA-DOB/HLA-DOA/HLA-DQA1/CD40/HLA-DMB/HLA-DPB1/HLA-DRB4	8
KEGG	hsa05166	Human T-cell leukemia virus 1 infection	33/794	222/8135	0.009096	0.0594	0.04651	CCND3/CD3D/E2F2/HLA-G/IL2RG/ADCY1/HLA-DOB/CDC20/HLA-A/CD3G/BUB3/HLA-DOA/LTA/IKBKG/ITGAL/GPS2/NFKBIA/IL2RB/NFKB1/PIK3CD/CD3E/TLN1/HLA-DQA1/ELK1/CD40/TLN2/HLA-DMB/HLA-DPB1/MAPK3/LCK/ETS1/HLA-DRB4/KAT5	33
KEGG	hsa04512	ECM-receptor interaction	16/794	88/8135	0.01032	0.06606	0.05172	ITGB7/COL4A1/THBS3/LAMB1/ITGA5/THBS2/LAMA2/CD36/RELN/ITGA7/LAMC2/COL6A3/ITGB4/FN1/COL4A2/COL6A6	16
KEGG	hsa04151	PI3K-Akt signaling pathway	48/794	354/8135	0.01121	0.06925	0.05422	HSP90B1/CCND3/PIK3CG/ITGB7/IL4R/IL7R/IFNAR2/COL4A1/IL2RG/LPAR5/VEGFB/SYK/THBS3/LAMB1/LPAR2/CD19/YWHAH/GNG11/MAGI1/ITGA5/JAK2/IKBKG/CSF1R/THBS2/LAMA2/IL2RB/NFKB1/PPP2R5A/RELN/PGF/ITGA7/PIK3CD/PRKCA/IFNAR1/LAMC2/COL6A3/MYB/IFNA16/ITGB4/FN1/PHLPP1/MAPK3/CDK6/IRS1/PIK3AP1/COL4A2/COL6A6/GRB2	48
KEGG	hsa04660	T cell receptor signaling pathway	18/794	104/8135	0.01125	0.06925	0.05422	ITK/CD3D/CD247/NFKBIE/CD3G/CBLB/CD8A/IKBKG/NFKBIA/LAT/NFKB1/RASGRP1/PIK3CD/CD3E/FYN/MAPK3/LCK/GRB2	18
KEGG	hsa05320	Autoimmune thyroid disease	11/794	53/8135	0.01194	0.07109	0.05565	HLA-G/HLA-DOB/HLA-A/HLA-DOA/GZMB/IFNA16/HLA-DQA1/CD40/HLA-DMB/HLA-DPB1/HLA-DRB4	11
KEGG	hsa04666	Fc gamma R-mediated phagocytosis	17/794	97/8135	0.012	0.07109	0.05565	INPP5D/PLCG2/ACTR2/SYK/WASF3/ARPC1A/LAT/RAC2/LYN/WAS/PIK3CD/VASP/PRKCA/AMPH/FCGR3B/MAPK3/PRKCB	17
KEGG	hsa00062	Fatty acid elongation	7/794	27/8135	0.01279	0.07442	0.05826	ECHS1/HADH/ACAA2/HADHB/ACOT2/ACOT1/ACOT4	7
KEGG	hsa04664	Fc epsilon RI signaling pathway	13/794	68/8135	0.01316	0.07522	0.05889	INPP5D/FCER1A/PLCG2/SYK/LAT/RAC2/LYN/PIK3CD/PRKCA/FYN/MAPK3/ALOX5AP/GRB2	13
KEGG	hsa03020	RNA polymerase	8/794	34/8135	0.01452	0.08069	0.06317	POLR2I/POLR2F/POLR2C/POLR3K/POLR2H/POLR2L/POLR2J3/TWISTNB	8
KEGG	hsa04141	Protein processing in endoplasmic reticulum	26/794	171/8135	0.01462	0.08069	0.06317	PDIA4/HSP90B1/DNAJB11/RPN2/DNAJC3/HYOU1/XBP1/DERL3/UBE2J1/TXNDC5/RRBP1/SSR4/RPN1/ATF6/UBXN6/UBE2D4/HSPA5/CRYAB/SEC63/EDEM2/P4HB/RNF185/LMAN2/SIL1/SEC61A1/CKAP4	26
KEGG	hsa00900	Terpenoid backbone biosynthesis	6/794	22/8135	0.01616	0.08767	0.06864	ACAT1/PMVK/FNTB/IDI1/MVD/ZMPSTE24	6
KEGG	hsa00130	Ubiquinone and other terpenoid-quinone biosynthesis	4/794	11/8135	0.01699	0.0906	0.07093	NQO1/VKORC1L1/COQ5/COQ3	4
KEGG	hsa00310	Lysine degradation	12/794	63/8135	0.01733	0.09089	0.07116	ECHS1/SETMAR/HADH/ACAT1/NSD1/PLOD3/PLOD1/SETD1A/ALDH7A1/EHMT1/EZH2/PLOD2	12
KEGG	hsa05332	Graft-versus-host disease	9/794	42/8135	0.01799	0.09287	0.07271	HLA-G/HLA-DOB/HLA-A/HLA-DOA/GZMB/HLA-DQA1/HLA-DMB/HLA-DPB1/HLA-DRB4	9
KEGG	hsa04657	IL-17 signaling pathway	16/794	94/8135	0.0189	0.09601	0.07517	MMP3/HSP90B1/MMP1/S100A8/CXCL6/IKBKG/NFKBIA/CXCL10/IL17RB/NFKB1/CXCL1/TRAF4/IKBKE/MAPK4/MAPK3/IL17D	16
KEGG	hsa00020	Citrate cycle (TCA cycle)	7/794	30/8135	0.0227	0.1135	0.08884	SUCLA2/PDHB/SDHB/IDH3B/SDHD/SUCLG1/PDHA1	7
KEGG	hsa04960	Aldosterone-regulated sodium reabsorption	8/794	37/8135	0.02383	0.1173	0.09183	NR3C2/PIK3CD/PRKCA/ATP1B1/SLC9A3R2/MAPK3/PRKCB/IRS1	8
KEGG	hsa05165	Human papillomavirus infection	43/794	331/8135	0.03053	0.1468	0.1149	IRF1/CCND3/ITGB7/HLA-G/STAT1/IFNAR2/COL4A1/HLA-A/THBS3/LAMB1/WNT11/MAGI1/ITGA5/MFNG/IKBKG/FZD5/THBS2/LAMA2/NFKB1/WNT1/PPP2R5A/HES1/MPP5/RELN/ITGA7/PIK3CD/SLC9A3R1/HEYL/IFNAR1/HES6/LAMC2/COL6A3/IFNA16/ITGB4/IKBKE/FN1/FZD2/MAPK3/CDK6/IRF3/COL4A2/COL6A6/GRB2	43
KEGG	hsa05133	Pertussis	13/794	76/8135	0.0312	0.1468	0.1149	IRF1/CXCL6/ITGA5/GNAI1/NFKB1/TICAM2/LY96/CD14/C2/MAPK3/C1QA/IRF3/C1S	13
KEGG	hsa03050	Proteasome	9/794	46/8135	0.03136	0.1468	0.1149	PSME4/PSMB10/PSMD8/PSMD4/PSMB7/PSME2/PSMB5/PSMD1/PSMB3	9
KEGG	hsa00640	Propanoate metabolism	7/794	32/8135	0.03166	0.1468	0.1149	ECHS1/SUCLA2/HIBCH/ACSS2/ACADS/SUCLG1/ACACA	7
KEGG	hsa04061	Viral protein interaction with cytokine and cytokine receptor	16/794	100/8135	0.0321	0.1468	0.1149	CXCL9/IL2RG/CXCL13/LTA/CXCL6/CCL5/XCL2/TNFRSF1B/CSF1R/CXCL10/IL10RA/IL2RB/CXCL1/CCR7/CCL13/TNFRSF14	16
KEGG	hsa04015	Rap1 signaling pathway	29/794	210/8135	0.03425	0.1544	0.1208	SKAP1/PFN2/ADCY1/LPAR5/VEGFB/RAPGEF6/LPAR2/RALGDS/ADORA2A/SIPA1/MAGI1/ITGAL/CSF1R/LAT/RAP1B/GNAI1/PLCB2/RAC2/PGF/PIK3CD/VASP/PRKCA/RAP1A/ACTB/TLN1/TLN2/MAPK3/PRKD2/PRKCB	29
KEGG	hsa04612	Antigen processing and presentation	13/794	78/8135	0.03766	0.1654	0.1295	TAP1/HLA-G/HLA-DOB/HLA-A/HLA-DOA/CD8A/HSPA5/PSME2/CIITA/HLA-DQA1/HLA-DMB/HLA-DPB1/HLA-DRB4	13
KEGG	hsa05146	Amoebiasis	16/794	102/8135	0.03773	0.1654	0.1295	COL4A1/ADCY1/LAMB1/LAMA2/NFKB1/PLCB2/CXCL1/PIK3CD/PRKCA/LAMC2/COL3A1/GNA15/CD14/FN1/PRKCB/COL4A2	16
KEGG	hsa04145	Phagosome	22/794	152/8135	0.03836	0.1659	0.1299	TAP1/HLA-G/HLA-DOB/HLA-A/THBS3/MARCO/HLA-DOA/ITGA5/CORO1A/THBS2/CYBB/TUBB2A/CD36/ACTB/HLA-DQA1/CD14/FCGR3B/SEC61A1/HLA-DMB/HLA-DPB1/RILP/HLA-DRB4	22
KEGG	hsa04668	TNF signaling pathway	17/794	112/8135	0.04332	0.1826	0.143	MMP3/IRF1/BIRC3/RPS6KA4/TRAF1/LTA/CXCL6/CCL5/IKBKG/TNFRSF1B/NFKBIA/CXCL10/NFKB1/RIPK3/CXCL1/PIK3CD/MAPK3	17
KEGG	hsa05171	Coronavirus disease - COVID-19	31/794	232/8135	0.04337	0.1826	0.143	MMP3/CFB/MMP1/STAT1/IFNAR2/PLCG2/SYK/IKBKG/NFKBIA/CXCL10/CYBB/NFKB1/PIK3CD/PRKCA/IFNAR1/RPL36/RPS16/IFNA16/IKBKE/C6/RPS21/RPL27/C2/MAPK3/PRKCB/C1QA/IRF3/C1S/RPS25/RPS4Y2/RPL13	31
KEGG	hsa04625	C-type lectin receptor signaling pathway	16/794	104/8135	0.04405	0.1826	0.143	IRF1/STAT1/PLCG2/SYK/CBLB/IKBKG/NFKBIA/EGR3/CARD9/NFKB1/PIK3CD/MAPKAPK2/ITPR3/IKBKE/MAPK3/IL17D	16
KEGG	hsa05150	Staphylococcus aureus infection	15/794	96/8135	0.04461	0.1826	0.143	CFB/HLA-DOB/HLA-DOA/ITGAL/FPR3/KRT13/HLA-DQA1/FCGR3B/HLA-DMB/C2/HLA-DPB1/DEFB1/C1QA/HLA-DRB4/C1S	15
KEGG	hsa04672	Intestinal immune network for IgA production	9/794	49/8135	0.04508	0.1826	0.143	ITGB7/TNFRSF17/HLA-DOB/HLA-DOA/HLA-DQA1/CD40/HLA-DMB/HLA-DPB1/HLA-DRB4	9
KEGG	hsa01212	Fatty acid metabolism	10/794	57/8135	0.04717	0.1887	0.1477	ECHS1/ACAA1/HADH/ACAA2/HADHB/ACAT1/ACADS/ACADL/ACADM/ACACA	10
KEGG	hsa05321	Inflammatory bowel disease	11/794	65/8135	0.04839	0.1912	0.1497	IL4R/STAT1/IL2RG/HLA-DOB/HLA-DOA/TBX21/NFKB1/HLA-DQA1/HLA-DMB/HLA-DPB1/HLA-DRB4	11
KEGG	hsa05162	Measles	20/794	139/8135	0.04922	0.1921	0.1504	CCND3/CD3D/STAT1/IFNAR2/IL2RG/CD3G/CBLB/IKBKG/NFKBIA/IL2RB/NFKB1/PIK3CD/IFNAR1/CD3E/IFNA16/IKBKE/IRF7/CDK6/MSN/IRF3	20
KEGG	hsa05160	Hepatitis C	22/794	157/8135	0.05204	0.2006	0.1571	IFIT1/E2F2/STAT1/IFNAR2/YWHAH/IKBKG/NFKBIA/CXCL10/CLDN5/NFKB1/PIK3CD/IFNAR1/IFNA16/IKBKE/MAPK3/IRF7/OCLN/CDK6/CLDN14/IRF3/RNASEL/GRB2	22
KEGG	hsa05131	Shigellosis	32/794	247/8135	0.05793	0.2169	0.1698	FNBP1L/DIAPH1/PFN2/PLCG2/ACTR2/FNBP1/ATG16L1/MAP1LC3B/ARPC1A/CCL5/ITGA5/IKBKG/RRAGA/HCLS1/UBE2D4/NFKBIA/CYTH2/NFKB1/PLCB2/CYTH4/HK3/PIK3CD/ACTB/ITPR3/TLN1/CD14/TLN2/MAPK3/RRAGD/WASL/IRF3/MYL9	32
KEGG	hsa04720	Long-term potentiation	11/794	67/8135	0.05828	0.2169	0.1698	ADCY1/GRIA2/RAP1B/PLCB2/PRKCA/RPS6KA1/RAP1A/ITPR3/MAPK3/PPP1R1A/PRKCB	11
KEGG	hsa05221	Acute myeloid leukemia	11/794	67/8135	0.05828	0.2169	0.1698	PIM2/LEF1/IKBKG/CSF1R/NFKB1/PIK3CD/CEBPA/RARA/CD14/MAPK3/GRB2	11
KEGG	hsa01250	Biosynthesis of nucleotide sugars	7/794	37/8135	0.06356	0.2338	0.183	GMPPA/PMM1/PGM1/GALK1/UAP1/HK3/MPI	7
KEGG	hsa04060	Cytokine-cytokine receptor interaction	37/794	295/8135	0.06542	0.2373	0.1858	CXCL9/TNFRSF17/CD27/IL4R/IL7R/IFNAR2/IL2RG/CXCL13/CNTFR/LTA/CXCL6/CCL5/XCL2/TNFRSF1B/CSF1R/CXCL10/LTB/IL17RB/IL10RA/IL27RA/IL2RB/CXCL1/CCR7/TNFRSF21/IFNAR1/GDF10/IL32/CTF1/IFNA16/AMH/CD40/CCL13/IL13RA2/TNFRSF14/TNFRSF4/BMP5/IL17D	37
KEGG	hsa00920	Sulfur metabolism	3/794	10/8135	0.06601	0.2373	0.1858	SUOX/MPST/PAPSS2	3
KEGG	hsa05142	Chagas disease	15/794	102/8135	0.06938	0.2467	0.1931	CD3D/CD247/ADCY1/CD3G/CCL5/IKBKG/NFKBIA/GNAI1/NFKB1/PLCB2/PIK3CD/CD3E/GNA15/MAPK3/C1QA	15
KEGG	hsa05135	Yersinia infection	19/794	137/8135	0.07322	0.2575	0.2016	ACTR2/ARPC1A/ITGA5/CD8A/IKBKG/NFKBIA/LAT/NFKB1/RAC2/WAS/PIK3CD/RPS6KA1/ACTB/ARHGEF1/FN1/MAPK3/WASL/LCK/IRF3	19
KEGG	hsa00910	Nitrogen metabolism	4/794	17/8135	0.07674	0.2669	0.209	CA12/CA5B/CA4/CA8	4
KEGG	hsa00514	Other types of O-glycan biosynthesis	8/794	47/8135	0.08258	0.2842	0.2225	C1GALT1/C1GALT1C1/MFNG/PLOD3/GALNT10/GALNT9/GALNT12/GALNT1	8
KEGG	hsa05223	Non-small cell lung cancer	11/794	72/8135	0.08853	0.3014	0.236	E2F2/STK4/PLCG2/PIK3CD/EML4/PRKCA/RET/MAPK3/PRKCB/CDK6/GRB2	11
KEGG	hsa04923	Regulation of lipolysis in adipocytes	9/794	56/8135	0.09107	0.3068	0.2402	ADCY1/PNPLA2/FABP4/GNAI1/LIPE/PIK3CD/AQP7/PTGS1/IRS1	9
KEGG	hsa04530	Tight junction	22/794	169/8135	0.09826	0.3275	0.2564	EZR/ACTR2/MICALL2/RAPGEF6/ARPC1A/MAGI1/HCLS1/EPB41L4B/CLDN5/WAS/MPP5/VASP/SLC9A3R1/RAP1A/ARHGEF18/ACTB/MYL6B/RAB8B/OCLN/MSN/CLDN14/MYL9	22
KEGG	hsa00520	Amino sugar and nucleotide sugar metabolism	8/794	49/8135	0.1	0.3301	0.2584	GMPPA/PMM1/PGM1/GALK1/UAP1/HK3/CYB5RL/MPI	8
KEGG	hsa05017	Spinocerebellar ataxia	19/794	143/8135	0.1017	0.3319	0.2599	XBP1/SP1/ATP2A3/PSMD8/ATXN1/GRIA2/PSMD4/PLCB2/PSMB7/RELN/PIK3CD/PRKCA/PSMB5/ITPR3/PSMD1/VLDLR/PRKCB/PSMB3/KAT5	19
KEGG	hsa05130	Pathogenic Escherichia coli infection	25/794	197/8135	0.1029	0.3326	0.2604	EZR/MYO1G/LPAR5/ACTR2/WASF3/LPAR2/ARPC1A/IKBKG/HCLS1/NFKBIA/CYTH2/TUBB2A/CLDN5/NFKB1/CYTH4/MYO5A/NCKAP1L/SLC9A3R1/FYN/ACTB/ARHGEF1/MAPK3/OCLN/CLDN14/WASL	25
KEGG	hsa00510	N-Glycan biosynthesis	8/794	50/8135	0.1095	0.3503	0.2743	MAN2A1/RPN2/FUT8/RPN1/ALG5/ALG12/MGAT1/DPM3	8
KEGG	hsa04918	Thyroid hormone synthesis	11/794	75/8135	0.1106	0.3503	0.2743	PDIA4/HSP90B1/ADCY1/TTR/GPX5/HSPA5/PLCB2/PRKCA/ATP1B1/ITPR3/PRKCB	11
KEGG	hsa00010	Glycolysis / Gluconeogenesis	10/794	67/8135	0.114	0.3575	0.2799	ADH1A/PGM1/PDHB/ADH1C/ACSS2/HK3/ADPGK/ALDH7A1/PDHA1/ADH1B	10
KEGG	hsa04380	Osteoclast differentiation	17/794	128/8135	0.117	0.361	0.2826	STAT1/IFNAR2/PLCG2/SYK/IKBKG/PPARG/CSF1R/NFKBIA/NFKB1/PIK3CD/IFNAR1/FYN/FCGR3B/LILRB3/MAPK3/LCK/GRB2	17
KEGG	hsa05323	Rheumatoid arthritis	13/794	93/8135	0.1173	0.361	0.2826	MMP3/MMP1/HLA-DOB/HLA-DOA/CXCL6/CCL5/ITGAL/LTB/CXCL1/HLA-DQA1/HLA-DMB/HLA-DPB1/HLA-DRB4	13
KEGG	hsa04926	Relaxin signaling pathway	17/794	129/8135	0.1232	0.3715	0.2909	MMP1/COL4A1/ADCY1/VEGFB/GNG11/NFKBIA/GNAI1/NFKB1/PLCB2/PIK3CD/PRKCA/COL3A1/GNA15/MMP2/MAPK3/COL4A2/GRB2	17
KEGG	hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	4/794	20/8135	0.1242	0.3715	0.2909	CHST15/CHPF/CHPF2/CHSY1	4
KEGG	hsa00670	One carbon pool by folate	4/794	20/8135	0.1242	0.3715	0.2909	MTHFD2L/SHMT2/ALDH1L1/MTHFS	4
KEGG	hsa04974	Protein digestion and absorption	14/794	103/8135	0.1267	0.3753	0.2938	COL4A1/COL5A2/COL8A1/SLC1A5/SLC7A7/COL6A3/COL11A2/COL3A1/ATP1B1/SLC36A1/SLC6A19/COL4A2/COL6A6/CTRB2	14
KEGG	hsa05170	Human immunodeficiency virus 1 infection	26/794	212/8135	0.131	0.3826	0.2995	TAP1/CD3D/CD247/HLA-G/PLCG2/APOBEC3D/HLA-A/CD3G/AP1G2/GNG11/IKBKG/TNFRSF1B/NFKBIA/CCNB1/GNAI1/NFKB1/RAC2/PIK3CD/PRKCA/CD3E/IFNA16/ITPR3/MAPK3/PRKCB/IRF3/BST2	26
KEGG	hsa00650	Butanoate metabolism	5/794	28/8135	0.1315	0.3826	0.2995	ECHS1/HADH/ACSM5/ACAT1/ACADS	5
KEGG	hsa00561	Glycerolipid metabolism	9/794	61/8135	0.1363	0.3929	0.3076	PNPLA2/GK2/LPL/DGKQ/ALDH7A1/GLYCTK/AGPAT2/MOGAT1/GPAM	9
KEGG	hsa04260	Cardiac muscle contraction	12/794	87/8135	0.1383	0.3951	0.3093	ATP2A3/UQCRC2/COX5B/COX6C/TPM1/COX7A1/CYC1/UQCRFS1/ATP1B1/COX6B1/COX8A/COX7C	12
KEGG	hsa05230	Central carbon metabolism in cancer	10/794	70/8135	0.141	0.3993	0.3126	SLC7A5/SCO2/PDHB/SLC16A3/HK3/PIK3CD/SLC1A5/RET/MAPK3/PDHA1	10
KEGG	hsa04936	Alcoholic liver disease	18/794	142/8135	0.1497	0.4176	0.3269	LEF1/ADH1A/ADH1C/IKBKG/NFKBIA/NFKB1/CXCL1/ALDH7A1/IFNA16/LY96/IKBKE/CD14/ACADM/C2/ACACA/C1QA/IRF3/ADH1B	18
KEGG	hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	3/794	14/8135	0.1501	0.4176	0.3269	FUT8/ST3GAL2/B4GALT4	3
KEGG	hsa01523	Antifolate resistance	5/794	30/8135	0.1631	0.4498	0.3522	ABCC3/IKBKG/NFKB1/SHMT2/ABCC4	5
KEGG	hsa04929	GnRH secretion	9/794	64/8135	0.1681	0.4598	0.36	PLCB2/PIK3CD/PRKCA/HCN1/ITPR3/KCNN2/MAPK3/PRKCB/KISS1R	9
KEGG	hsa00562	Inositol phosphate metabolism	10/794	73/8135	0.1711	0.464	0.3632	PIK3CG/INPP5D/PLCG2/IMPA2/ISYNA1/PLCB2/PIK3CD/SACM1L/PI4K2B/ITPK1	10
KEGG	hsa00604	Glycosphingolipid biosynthesis - ganglio series	3/794	15/8135	0.1747	0.4681	0.3665	ST6GALNAC4/ST6GALNAC6/ST3GAL2	3
KEGG	hsa00513	Various types of N-glycan biosynthesis	6/794	39/8135	0.1755	0.4681	0.3665	MAN2A1/RPN2/FUT8/RPN1/ALG12/MGAT1	6
KEGG	hsa05202	Transcriptional misregulation in cancer	23/794	193/8135	0.1825	0.4826	0.3778	MMP3/BIRC3/ITGB7/ETV6/FUT8/SP1/TRAF1/PPARG/CSF1R/FLI1/IL2RB/NFKB1/WT1/GZMB/CEBPA/ETV5/NUPR1/RARA/CD40/CD14/MLLT3/NFKBIZ/TFE3	23
KEGG	hsa03320	PPAR signaling pathway	10/794	75/8135	0.1927	0.5038	0.3944	MMP1/ACAA1/GK2/PPARG/FABP4/CD36/ACADL/LPL/AQP7/ACADM	10
KEGG	hsa04072	Phospholipase D signaling pathway	18/794	148/8135	0.1936	0.5038	0.3944	PIK3CG/FCER1A/PLCG2/ADCY1/LPAR5/SYK/LPAR2/RALGDS/CYTH2/PLCB2/CYTH4/DGKQ/PIK3CD/PRKCA/FYN/AGPAT2/MAPK3/GRB2	18
KEGG	hsa00480	Glutathione metabolism	8/794	58/8135	0.201	0.5186	0.406	PRDX6/ANPEP/GPX5/MGST3/MGST2/LANCL1/NAT8/GPX4	8
KEGG	hsa04971	Gastric acid secretion	10/794	76/8135	0.2039	0.5216	0.4084	EZR/ADCY1/MYLK4/GNAI1/PLCB2/PRKCA/ACTB/ATP1B1/ITPR3/PRKCB	10
KEGG	hsa04216	Ferroptosis	6/794	41/8135	0.2063	0.5216	0.4084	SLC39A14/MAP1LC3B/SAT2/CYBB/PCBP1/GPX4	6
KEGG	hsa05163	Human cytomegalovirus infection	26/794	225/8135	0.207	0.5216	0.4084	TAP1/E2F2/HLA-G/SP1/ADCY1/HLA-A/GNG11/CCL5/IKBKG/NFKBIA/IL10RA/GNAI1/NFKB1/PLCB2/RAC2/PIK3CD/PRKCA/IFNA16/ITPR3/ELK1/ARHGEF1/MAPK3/PRKCB/CDK6/IRF3/GRB2	26
KEGG	hsa00051	Fructose and mannose metabolism	5/794	33/8135	0.2153	0.534	0.4181	GMPPA/PMM1/HK3/PFKFB1/MPI	5
KEGG	hsa04130	SNARE interactions in vesicular transport	5/794	33/8135	0.2153	0.534	0.4181	STX1A/USE1/STX19/SNAP23/VAMP8	5
KEGG	hsa05152	Tuberculosis	21/794	180/8135	0.2238	0.5441	0.426	STAT1/VDR/HLA-DOB/SYK/CEBPG/HLA-DOA/JAK2/CORO1A/CARD9/IL10RA/NFKB1/CIITA/IFNA16/HLA-DQA1/CD14/IRAK2/FCGR3B/HLA-DMB/HLA-DPB1/MAPK3/HLA-DRB4	21
KEGG	hsa04810	Regulation of actin cytoskeleton	25/794	218/8135	0.224	0.5441	0.426	EZR/ITGB7/FGD3/DIAPH1/PFN2/LPAR5/ACTR2/LPAR2/ARPC1A/PPP1R12C/ITGA5/ITGAL/MYLK4/RAC2/ITGA7/PIK3CD/NCKAP1L/ACTB/ITGB4/ARHGEF1/FN1/MAPK3/MSN/WASL/MYL9	25
KEGG	hsa04730	Long-term depression	8/794	60/8135	0.2276	0.5441	0.426	GRIA2/GNAI1/PLCB2/LYN/PRKCA/ITPR3/MAPK3/PRKCB	8
KEGG	hsa04978	Mineral absorption	8/794	60/8135	0.2276	0.5441	0.426	MT1F/MT1G/MT1H/VDR/ATP1B1/TRPM7/SLC6A19/MT1A	8
KEGG	hsa04920	Adipocytokine signaling pathway	9/794	69/8135	0.2279	0.5441	0.426	NFKBIE/JAK2/IKBKG/TNFRSF1B/NFKBIA/CD36/NFKB1/POMC/IRS1	9
KEGG	hsa05161	Hepatitis B	19/794	162/8135	0.2309	0.5474	0.4286	E2F2/STAT1/JAK2/IKBKG/NFKBIA/EGR3/NFKB1/TICAM2/PIK3CD/PRKCA/IFNAR1/IFNA16/IKBKE/ELK1/MAPK3/IRF7/PRKCB/IRF3/GRB2	19
KEGG	hsa01240	Biosynthesis of cofactors	18/794	153/8135	0.2346	0.5485	0.4295	UROD/SPR/NQO1/GMPPA/MTHFD2L/PMM1/VKORC1L1/DHRS3/ALAD/COQ5/RDH11/SHMT2/NME4/NMNAT3/PPCS/NADSYN1/COQ3/MPI	18
KEGG	hsa04070	Phosphatidylinositol signaling system	12/794	97/8135	0.2348	0.5485	0.4295	INPP5D/PLCG2/IMPA2/PLCB2/DGKQ/PIK3CD/SACM1L/PRKCA/ITPR3/PRKCB/PI4K2B/ITPK1	12
KEGG	hsa00790	Folate biosynthesis	4/794	26/8135	0.2448	0.5657	0.4429	SPR/PCBD1/QDPR/AKR1C3	4
KEGG	hsa05231	Choline metabolism in cancer	12/794	98/8135	0.2457	0.5657	0.4429	SP1/WASF3/RALGDS/RAC2/DGKQ/WAS/PIK3CD/PRKCA/MAPK3/SLC22A4/PRKCB/GRB2	12
KEGG	hsa04520	Adherens junction	9/794	71/8135	0.2537	0.58	0.4541	PTPN1/LEF1/WASF3/RAC2/WAS/FYN/ACTB/MAPK3/WASL	9
KEGG	hsa04137	Mitophagy - animal	9/794	72/8135	0.267	0.598	0.4682	FIS1/TBC1D17/SP1/MAP1LC3B/BCL2L13/USP8/GABARAPL2/PINK1/TFE3	9
KEGG	hsa01040	Biosynthesis of unsaturated fatty acids	4/794	27/8135	0.2671	0.598	0.4682	ACAA1/ACOT2/ACOT1/ACOT4	4
KEGG	hsa05205	Proteoglycans in cancer	23/794	205/8135	0.2698	0.598	0.4682	EZR/PLCG2/WNT11/PPP1R12C/ITGA5/HCLS1/FZD5/WNT1/PIK3CD/PRKCA/ACTB/MMP2/ITPR3/ELK1/ARHGEF1/FN1/GPC3/FZD2/MAPK3/PRKCB/MSN/HSPB2/GRB2	23
KEGG	hsa04722	Neurotrophin signaling pathway	14/794	119/8135	0.2699	0.598	0.4682	ARHGDIB/PLCG2/NFKBIE/NFKBIA/RAP1B/NFKB1/PIK3CD/RPS6KA1/RAP1A/MAPKAPK2/IRAK2/MAPK3/IRS1/GRB2	14
KEGG	hsa00350	Tyrosine metabolism	5/794	36/8135	0.2719	0.598	0.4682	ADH1A/ADH1C/PNMT/FAH/ADH1B	5
KEGG	hsa02010	ABC transporters	6/794	45/8135	0.2729	0.598	0.4682	TAP1/ABCC3/ABCA9/ABCA8/DEFB1/ABCC4	6
KEGG	hsa04146	Peroxisome	10/794	82/8135	0.2765	0.6018	0.4712	ACAA1/PHYH/PRDX5/PXMP2/PMVK/PEX7/ECH1/AGXT/HAO1/CRAT	10
KEGG	hsa04916	Melanogenesis	12/794	101/8135	0.2794	0.6042	0.473	ADCY1/LEF1/WNT11/FZD5/GNAI1/PLCB2/WNT1/PRKCA/POMC/FZD2/MAPK3/PRKCB	12
KEGG	hsa04972	Pancreatic secretion	12/794	102/8135	0.291	0.6216	0.4867	CD38/ATP2A3/ADCY1/PLA2G2A/RAP1B/PLCB2/PRKCA/RAP1A/ATP1B1/ITPR3/PRKCB/CTRB2	12
KEGG	hsa00250	Alanine, aspartate and glutamate metabolism	5/794	37/8135	0.2914	0.6216	0.4867	ASPA/ALDH4A1/AGXT/NIT2/NAT8L	5
KEGG	hsa04725	Cholinergic synapse	13/794	113/8135	0.3079	0.6472	0.5067	PIK3CG/ADCY1/GNG11/JAK2/GNAI1/PLCB2/PIK3CD/PRKCA/FYN/ITPR3/MAPK3/PRKCB/KCNJ4	13
KEGG	hsa05214	Glioma	9/794	75/8135	0.308	0.6472	0.5067	E2F2/PLCG2/CAMK1G/PIK3CD/PRKCA/MAPK3/PRKCB/CDK6/GRB2	9
KEGG	hsa05132	Salmonella infection	27/794	249/8135	0.3095	0.6472	0.5067	HSP90B1/PIK3CG/BIRC3/PFN2/ACTR2/LEF1/WASF3/DCTN3/ARPC1A/DCTN2/IKBKG/NFKBIA/CYTH2/TUBB2A/NFKB1/RIPK3/CYTH4/PIK3CD/NCKAP1L/ACTB/LY96/CD14/DYNLL2/MAPK3/RILP/WASL/MYL9	27
KEGG	hsa04392	Hippo signaling pathway - multiple species	4/794	29/8135	0.3125	0.6494	0.5084	RASSF4/WTIP/RASSF2/STK3	4
KEGG	hsa04630	JAK-STAT signaling pathway	18/794	162/8135	0.3161	0.6526	0.5109	CCND3/IL4R/IL7R/STAT1/IFNAR2/IL2RG/CNTFR/JAK2/IL10RA/IL27RA/IL2RB/PIK3CD/IFNAR1/CTF1/IFNA16/IL13RA2/IL17D/GRB2	18
KEGG	hsa05212	Pancreatic cancer	9/794	76/8135	0.322	0.6605	0.5171	E2F2/STAT1/RALGDS/IKBKG/NFKB1/RAC2/PIK3CD/MAPK3/CDK6	9
KEGG	hsa04911	Insulin secretion	10/794	86/8135	0.3285	0.6696	0.5243	ADCY1/STX1A/KCNMB1/PLCB2/PRKCA/ATP1B1/ITPR3/KCNN2/RIMS2/PRKCB	10
KEGG	hsa04921	Oxytocin signaling pathway	17/794	154/8135	0.3328	0.6722	0.5263	PIK3CG/CD38/ADCY1/CAMK1G/PPP1R12C/MYLK4/GNAI1/PLCB2/PRKCA/ACTB/MYL6B/ITPR3/ELK1/MAPK3/PRKCB/KCNJ4/MYL9	17
KEGG	hsa00030	Pentose phosphate pathway	4/794	30/8135	0.3355	0.6722	0.5263	H6PD/PGM1/GLYCTK/RBKS	4
KEGG	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	9/794	77/8135	0.3361	0.6722	0.5263	ITGB7/ATP2A3/LEF1/SGCB/ITGA5/LAMA2/ITGA7/ACTB/ITGB4	9
KEGG	hsa04928	Parathyroid hormone synthesis, secretion and action	12/794	106/8135	0.3384	0.6726	0.5266	VDR/SP1/ADCY1/GNAI1/PLCB2/MMP25/SLC9A3R1/PRKCA/ITPR3/ARHGEF1/MAPK3/PRKCB	12
KEGG	hsa04934	Cushing syndrome	17/794	155/8135	0.3428	0.6763	0.5295	E2F2/SP1/ADCY1/LEF1/WNT11/USP8/FZD5/RAP1B/GNAI1/PLCB2/WNT1/POMC/RAP1A/ITPR3/FZD2/MAPK3/CDK6	17
KEGG	hsa04110	Cell cycle	14/794	126/8135	0.3455	0.6763	0.5295	CCND3/E2F2/CDC7/CDKN1C/E2F5/CDC20/BUB3/YWHAH/TTK/CCNB1/CDKN2D/MCM4/CDC14A/CDK6	14
KEGG	hsa05215	Prostate cancer	11/794	97/8135	0.3466	0.6763	0.5295	MMP3/HSP90B1/E2F2/LEF1/IKBKG/NFKBIA/NFKB1/PIK3CD/ETV5/MAPK3/GRB2	11
KEGG	hsa04370	VEGF signaling pathway	7/794	59/8135	0.3526	0.6838	0.5354	PLCG2/RAC2/PIK3CD/PRKCA/MAPKAPK2/MAPK3/PRKCB	7
KEGG	hsa04540	Gap junction	10/794	88/8135	0.3553	0.6849	0.5362	ADCY1/MAP3K2/TUBB2A/GNAI1/PLCB2/PRKCA/ITPR3/MAPK3/PRKCB/GRB2	10
KEGG	hsa00410	beta-Alanine metabolism	4/794	31/8135	0.3586	0.6859	0.537	ECHS1/HIBCH/ACADS/ALDH7A1	4
KEGG	hsa05144	Malaria	6/794	50/8135	0.3616	0.6859	0.537	GYPC/THBS3/ITGAL/THBS2/CD36/CD40	6
KEGG	hsa04727	GABAergic synapse	10/794	89/8135	0.3688	0.6859	0.537	ADCY1/GNG11/SLC38A1/TRAK2/GNAI1/GABARAPL2/PRKCA/SLC6A1/PRKCB/SLC38A5	10
KEGG	hsa05219	Bladder cancer	5/794	41/8135	0.3713	0.6859	0.537	MMP1/E2F2/TYMP/MMP2/MAPK3	5
KEGG	hsa03010	Ribosome	17/794	158/8135	0.373	0.6859	0.537	MRPS15/MRPL24/MRPS11/MRPL33/MRPS9/MRPL16/RPL36/RPS16/MRPL35/MRPS18C/MRPL34/RPS21/RPL27/RPS25/MRPL22/RPS4Y2/RPL13	17
KEGG	hsa05225	Hepatocellular carcinoma	18/794	168/8135	0.3743	0.6859	0.537	E2F2/NQO1/PLCG2/LEF1/WNT11/MGST3/FZD5/WNT1/PIK3CD/PRKCA/ACTB/MGST2/ELK1/FZD2/MAPK3/PRKCB/CDK6/GRB2	18
KEGG	hsa04622	RIG-I-like receptor signaling pathway	8/794	70/8135	0.3747	0.6859	0.537	IKBKG/NFKBIA/CXCL10/NFKB1/IFNA16/IKBKE/IRF7/IRF3	8
KEGG	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	8/794	70/8135	0.3747	0.6859	0.537	PLCG2/CSK/CCL5/IKBKG/NFKBIA/NFKB1/LYN/CXCL1	8
KEGG	hsa04071	Sphingolipid signaling pathway	13/794	119/8135	0.3772	0.6859	0.537	FCER1A/GNAI1/NFKB1/PLCB2/PPP2R5A/RAC2/PIK3CD/PRKCA/FYN/MAPK3/PRKCB/S1PR3/S1PR4	13
KEGG	hsa04935	Growth hormone synthesis, secretion and action	13/794	119/8135	0.3772	0.6859	0.537	STAT1/PLCG2/ADCY1/JAK2/GNAI1/PLCB2/PIK3CD/PRKCA/ITPR3/MAPK3/PRKCB/IRS1/GRB2	13
KEGG	hsa04913	Ovarian steroidogenesis	6/794	51/8135	0.3797	0.6865	0.5374	ADCY1/ACOT2/AKR1C3/ACOT1/ACOT4/HSD17B1	6
KEGG	hsa04014	Ras signaling pathway	24/794	232/8135	0.4132	0.7428	0.5815	RASAL3/STK4/PLCG2/VEGFB/RALGDS/GNG11/IKBKG/PLA2G2A/CSF1R/LAT/RAP1B/NFKB1/RAC2/PGF/RASGRP1/PIK3CD/PRKCA/RAP1A/RGL1/ELK1/MAPK3/PRKCB/ETS1/GRB2	24
KEGG	hsa00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	3/794	24/8135	0.4198	0.7506	0.5876	NDST2/EXT1/HS3ST2	3
KEGG	hsa04912	GnRH signaling pathway	10/794	93/8135	0.4231	0.7523	0.5889	ADCY1/MAP3K2/PLCB2/PRKCA/MMP2/ITPR3/ELK1/MAPK3/PRKCB/GRB2	10
KEGG	hsa05203	Viral carcinogenesis	21/794	204/8135	0.4323	0.7643	0.5983	CCND3/HLA-G/GTF2H4/SYK/CDC20/HLA-A/YWHAH/TRAF1/IKBKG/MRPS18B/NFKBIA/EGR3/NFKB1/LYN/PIK3CD/MAPKAPK2/MAPK3/IRF7/CDK6/IRF3/GRB2	21
KEGG	hsa04270	Vascular smooth muscle contraction	14/794	134/8135	0.436	0.7663	0.5999	ADCY1/KCNMB1/ADORA2A/PPP1R12C/PLA2G2A/MYLK4/PLCB2/PRKCA/MYL6B/ITPR3/ARHGEF1/MAPK3/PRKCB/MYL9	14
KEGG	hsa00603	Glycosphingolipid biosynthesis - globo and isoglobo series	2/794	15/8135	0.4382	0.7663	0.5999	GBGT1/ST3GAL2	2
KEGG	hsa05414	Dilated cardiomyopathy	10/794	96/8135	0.4639	0.8009	0.627	ITGB7/ATP2A3/ADCY1/SGCB/ITGA5/LAMA2/TPM1/ITGA7/ACTB/ITGB4	10
KEGG	hsa05220	Chronic myeloid leukemia	8/794	76/8135	0.4666	0.8009	0.627	E2F2/IKBKG/NFKBIA/NFKB1/PIK3CD/MAPK3/CDK6/GRB2	8
KEGG	hsa00500	Starch and sucrose metabolism	4/794	36/8135	0.4722	0.8009	0.627	PGM1/HK3/GYG2/TREH	4
KEGG	hsa00760	Nicotinate and nicotinamide metabolism	4/794	36/8135	0.4722	0.8009	0.627	CD38/NMNAT3/NADSYN1/SIRT2	4
KEGG	hsa03030	DNA replication	4/794	36/8135	0.4722	0.8009	0.627	POLE4/LIG1/SSBP1/MCM4	4
KEGG	hsa00563	Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	3/794	26/8135	0.473	0.8009	0.627	PIGM/GPAA1/PIGY	3
KEGG	hsa04713	Circadian entrainment	10/794	97/8135	0.4773	0.8039	0.6294	ADCY1/GRIA2/GNG11/PER3/GNAI1/PLCB2/PRKCA/ITPR3/MAPK3/PRKCB	10
KEGG	hsa05100	Bacterial invasion of epithelial cells	8/794	77/8135	0.4818	0.8072	0.6319	ACTR2/ARPC1A/ITGA5/HCLS1/PIK3CD/ACTB/FN1/WASL	8
KEGG	hsa03420	Nucleotide excision repair	5/794	47/8135	0.4903	0.8094	0.6337	GTF2H4/GTF2H5/POLE4/LIG1/ERCC5	5
KEGG	hsa04973	Carbohydrate digestion and absorption	5/794	47/8135	0.4903	0.8094	0.6337	PLCB2/HK3/PIK3CD/ATP1B1/PRKCB	5
KEGG	hsa04925	Aldosterone synthesis and secretion	10/794	98/8135	0.4908	0.8094	0.6337	ADCY1/CAMK1G/PLCB2/LIPE/PRKCA/POMC/ATP1B1/ITPR3/PRKD2/PRKCB	10
KEGG	hsa05216	Thyroid cancer	4/794	37/8135	0.4941	0.8094	0.6337	LEF1/PPARG/RET/MAPK3	4
KEGG	hsa00980	Metabolism of xenobiotics by cytochrome P450	8/794	78/8135	0.4968	0.8094	0.6337	ADH1A/ADH1C/MGST3/MGST2/AKR7A3/CYP2S1/AKR7A2/ADH1B	8
KEGG	hsa00830	Retinol metabolism	7/794	68/8135	0.5004	0.8094	0.6337	ADH1A/DHRS3/ADH1C/RDH11/CYP3A7/CYP2S1/ADH1B	7
KEGG	hsa04066	HIF-1 signaling pathway	11/794	109/8135	0.5008	0.8094	0.6337	TIMP1/PLCG2/PDHB/CYBB/NFKB1/HK3/PIK3CD/PRKCA/MAPK3/PDHA1/PRKCB	11
KEGG	hsa00240	Pyrimidine metabolism	6/794	58/8135	0.5045	0.8113	0.6352	ENTPD1/NME4/HDDC2/TYMP/NUDT2/DCTPP1	6
KEGG	hsa05211	Renal cell carcinoma	7/794	69/8135	0.5163	0.8261	0.6467	RAP1B/PIK3CD/RAP1A/TFE3/MAPK3/ETS1/GRB2	7
KEGG	hsa05410	Hypertrophic cardiomyopathy	9/794	90/8135	0.5216	0.8304	0.6501	ITGB7/ATP2A3/SGCB/ITGA5/LAMA2/TPM1/ITGA7/ACTB/ITGB4	9
KEGG	hsa04120	Ubiquitin mediated proteolysis	14/794	142/8135	0.5261	0.8328	0.652	BIRC3/UBE2Z/DET1/UBE2J1/CDC20/CBLB/UBE2D4/UBE2B/UBA7/KLHL13/BIRC7/UBA6/FBXW7/TRIM32	14
KEGG	hsa05030	Cocaine addiction	5/794	49/8135	0.5283	0.8328	0.652	PPP1R1B/GRIA2/GNAI1/NFKB1/DLG4	5
KEGG	hsa04917	Prolactin signaling pathway	7/794	70/8135	0.532	0.8346	0.6534	IRF1/STAT1/JAK2/NFKB1/PIK3CD/MAPK3/GRB2	7
KEGG	hsa05110	Vibrio cholerae infection	5/794	50/8135	0.5468	0.8536	0.6683	PDIA4/PLCG2/PRKCA/ACTB/SEC61A1	5
KEGG	hsa04724	Glutamatergic synapse	11/794	114/8135	0.5629	0.8651	0.6773	ADCY1/GRIA2/GNG11/SLC38A1/GNAI1/PLCB2/DLG4/PRKCA/ITPR3/MAPK3/PRKCB	11
KEGG	hsa04150	mTOR signaling pathway	15/794	156/8135	0.5649	0.8651	0.6773	SLC7A5/STRADB/WNT11/RRAGA/FZD5/WNT1/PIK3CD/PRKCA/RPS6KA1/FZD2/MAPK3/PRKCB/IRS1/RRAGD/GRB2	15
KEGG	hsa04218	Cellular senescence	15/794	156/8135	0.5649	0.8651	0.6773	CCND3/E2F2/HLA-G/E2F5/HLA-A/CCNB1/NFKB1/PIK3CD/ZFP36L1/MAPKAPK2/ITPR3/TRPM7/MAPK3/CDK6/ETS1	15
KEGG	hsa00330	Arginine and proline metabolism	5/794	51/8135	0.565	0.8651	0.6773	SAT2/ALDH18A1/ALDH7A1/ALDH4A1/CKMT1A	5
KEGG	hsa04390	Hippo signaling pathway	15/794	157/8135	0.5752	0.8765	0.6862	CCND3/BIRC3/LEF1/WNT11/YWHAH/FZD5/WTIP/WNT1/MPP5/DLG4/ACTB/STK3/AMH/FZD2/BMP5	15
KEGG	hsa00052	Galactose metabolism	3/794	31/8135	0.5947	0.8933	0.6994	PGM1/GALK1/HK3	3
KEGG	hsa04915	Estrogen signaling pathway	13/794	138/8135	0.5968	0.8933	0.6994	HSP90B1/SP1/ADCY1/GNAI1/PLCB2/PIK3CD/POMC/KRT13/MMP2/ITPR3/RARA/MAPK3/GRB2	13
KEGG	hsa00380	Tryptophan metabolism	4/794	42/8135	0.597	0.8933	0.6994	ECHS1/HADH/ACAT1/ALDH7A1	4
KEGG	hsa04012	ErbB signaling pathway	8/794	85/8135	0.5974	0.8933	0.6994	PLCG2/CBLB/PIK3CD/PRKCA/ELK1/MAPK3/PRKCB/GRB2	8
KEGG	hsa04961	Endocrine and other factor-regulated calcium reabsorption	5/794	53/8135	0.6002	0.8933	0.6994	VDR/PLCB2/PRKCA/ATP1B1/PRKCB	5
KEGG	hsa04975	Fat digestion and absorption	4/794	43/8135	0.616	0.9126	0.7145	PLA2G2A/ACAT1/CD36/AGPAT2	4
KEGG	hsa04962	Vasopressin-regulated water reabsorption	4/794	44/8135	0.6345	0.9322	0.7298	ARHGDIB/DCTN2/DYNLL2/AQP2	4
KEGG	hsa04068	FoxO signaling pathway	12/794	131/8135	0.636	0.9322	0.7298	IL7R/STK4/CCNB1/GABARAPL2/PIK3CD/CDKN2D/PRMT1/PLK4/MAPK3/IRS1/S1PR4/GRB2	12
KEGG	hsa03410	Base excision repair	3/794	33/8135	0.6379	0.9322	0.7298	POLE4/LIG1/XRCC1	3
KEGG	hsa04919	Thyroid hormone signaling pathway	11/794	121/8135	0.6441	0.9345	0.7316	STAT1/PLCG2/ATP2A3/THRA/PLCB2/PIK3CD/PRKCA/ACTB/ATP1B1/MAPK3/PRKCB	11
KEGG	hsa00340	Histidine metabolism	2/794	22/8135	0.6475	0.9345	0.7316	ASPA/ALDH7A1	2
KEGG	hsa04010	MAPK signaling pathway	27/794	294/8135	0.6624	0.9345	0.7316	PTPN7/ECSIT/STK4/MAPT/VEGFB/MAP3K2/MAP4K1/RPS6KA4/IKBKG/CSF1R/DAXX/RAP1B/NFKB1/DUSP5/RAC2/PGF/RASGRP1/PRKCA/RPS6KA1/RAP1A/MAPKAPK2/STK3/ELK1/CD14/MAPK3/PRKCB/GRB2	27
KEGG	hsa01521	EGFR tyrosine kinase inhibitor resistance	7/794	79/8135	0.6627	0.9345	0.7316	PLCG2/JAK2/PIK3CD/PRKCA/MAPK3/PRKCB/GRB2	7
KEGG	hsa03018	RNA degradation	7/794	79/8135	0.6627	0.9345	0.7316	PABPC1L/CNOT10/PABPC4L/PABPC1/EXOSC7/LSM3/CNOT4	7
KEGG	hsa05168	Herpes simplex virus 1 infection	46/794	495/8135	0.6644	0.9345	0.7316	TAP1/BIRC3/ZNF433/ZNF275/HLA-G/STAT1/IFNAR2/ZNF583/HLA-DOB/SYK/HLA-A/ZNF354B/ZNF584/HLA-DOA/ZNF749/LTA/CCL5/ITGA5/JAK2/IKBKG/NFKBIA/ZNF442/CARD9/DAXX/ZNF19/NFKB1/ZNF517/PIK3CD/HCFC1/ZNF746/IFNAR1/IFNA16/ZNF599/IKBKE/HLA-DQA1/TNFRSF14/HLA-DMB/HLA-DPB1/IRF7/ZNF766/ZNF878/IRF3/HLA-DRB4/ZNF596/BST2/RNASEL	46
KEGG	hsa05134	Legionellosis	5/794	57/8135	0.6654	0.9345	0.7316	BCL2L13/NFKBIA/NFKB1/CXCL1/CD14	5
KEGG	hsa04930	Type II diabetes mellitus	4/794	46/8135	0.6696	0.9345	0.7316	HK3/PIK3CD/MAPK3/IRS1	4
KEGG	hsa03430	Mismatch repair	2/794	23/8135	0.6718	0.9345	0.7316	LIG1/SSBP1	2
KEGG	hsa04964	Proximal tubule bicarbonate reclamation	2/794	23/8135	0.6718	0.9345	0.7316	CA4/ATP1B1	2
KEGG	hsa04310	Wnt signaling pathway	15/794	167/8135	0.6726	0.9345	0.7316	CTNNBIP1/CCND3/ROR2/LEF1/WNT11/FZD5/PLCB2/WNT1/RAC2/PRKCA/GPC4/DKK4/WIF1/FZD2/PRKCB	15
KEGG	hsa04024	cAMP signaling pathway	20/794	221/8135	0.6746	0.9345	0.7316	ATP2A3/ADCY1/PPP1R1B/GRIA2/ADORA2A/NFKBIA/RAP1B/GNAI1/NFKB1/RAC2/LIPE/PIK3CD/POMC/RAP1A/ATP1B1/AMH/FXYD1/MAPK3/ABCC4/MYL9	20
KEGG	hsa05213	Endometrial cancer	5/794	58/8135	0.6806	0.9371	0.7337	LEF1/PIK3CD/ELK1/MAPK3/GRB2	5
KEGG	hsa04210	Apoptosis	12/794	136/8135	0.6873	0.9371	0.7337	BIRC3/TRAF1/IKBKG/NFKBIA/DAXX/NFKB1/PIK3CD/GZMB/ACTB/ITPR3/MAPK3/SPTAN1	12
KEGG	hsa05322	Systemic lupus erythematosus	12/794	136/8135	0.6873	0.9371	0.7337	HLA-DOB/HLA-DOA/HLA-DQA1/C6/CD40/FCGR3B/HLA-DMB/C2/HLA-DPB1/C1QA/HLA-DRB4/C1S	12
KEGG	hsa05224	Breast cancer	13/794	147/8135	0.6882	0.9371	0.7337	E2F2/SP1/LEF1/WNT11/FZD5/WNT1/HES1/PIK3CD/HEYL/FZD2/MAPK3/CDK6/GRB2	13
KEGG	hsa04977	Vitamin digestion and absorption	2/794	24/8135	0.6947	0.941	0.7367	RBP2/BTD	2
KEGG	hsa04726	Serotonergic synapse	10/794	115/8135	0.6969	0.941	0.7367	GNG11/GNAI1/PLCB2/PRKCA/ITPR3/KCNN2/MAPK3/PTGS1/PRKCB/CYP4X1	10
KEGG	hsa05143	African trypanosomiasis	3/794	37/8135	0.7144	0.959	0.7508	PLCB2/PRKCA/PRKCB	3
KEGG	hsa00592	alpha-Linolenic acid metabolism	2/794	25/8135	0.7163	0.959	0.7508	ACAA1/PLA2G2A	2
KEGG	hsa00590	Arachidonic acid metabolism	5/794	61/8135	0.7233	0.9644	0.7551	PTGES/GPX5/PLA2G2A/AKR1C3/PTGS1	5
KEGG	hsa01232	Nucleotide metabolism	7/794	85/8135	0.7361	0.9697	0.7592	ENTPD1/NME4/HDDC2/TYMP/ADA/IMPDH2/DCTPP1	7
KEGG	hsa04950	Maturity onset diabetes of the young	2/794	26/8135	0.7365	0.9697	0.7592	HES1/ONECUT1	2
KEGG	hsa04931	Insulin resistance	9/794	108/8135	0.7395	0.9697	0.7592	PTPN1/NFKBIA/CD36/NFKB1/PIK3CD/RPS6KA1/MLXIPL/PRKCB/IRS1	9
KEGG	hsa03015	mRNA surveillance pathway	8/794	97/8135	0.7428	0.9697	0.7592	SAP18/PABPC1L/WDR33/FIP1L1/PPP2R5A/CPSF3/PABPC4L/PABPC1	8
KEGG	hsa00270	Cysteine and methionine metabolism	4/794	51/8135	0.747	0.9697	0.7592	MPST/CBS/BHMT/SDS	4
KEGG	hsa03250	Viral life cycle - HIV-1	5/794	63/8135	0.7494	0.9697	0.7592	APOBEC3D/SUPT5H/BICD2/MLLT3/BST2	5
KEGG	hsa05217	Basal cell carcinoma	5/794	63/8135	0.7494	0.9697	0.7592	LEF1/WNT11/FZD5/WNT1/FZD2	5
KEGG	hsa04550	Signaling pathways regulating pluripotency of stem cells	12/794	143/8135	0.7515	0.9697	0.7592	WNT11/JAK2/FZD5/WNT1/ISL1/PIK3CD/FZD2/MAPK3/MYF5/PCGF1/ONECUT1/GRB2	12
KEGG	hsa04022	cGMP-PKG signaling pathway	14/794	167/8135	0.7648	0.9829	0.7695	PIK3CG/ATP2A3/ADCY1/ADRA2A/KCNMB1/MYLK4/GNAI1/PLCB2/VASP/ATP1B1/ITPR3/MAPK3/IRS1/MYL9	14
KEGG	hsa04927	Cortisol synthesis and secretion	5/794	65/8135	0.7737	0.9903	0.7753	SP1/ADCY1/PLCB2/POMC/ITPR3	5
KEGG	hsa04360	Axon guidance	15/794	182/8135	0.7923	0.9933	0.7776	SEMA4A/SEMA4D/ABLIM3/PLCG2/GNAI1/RAC2/RGS3/SEMA4B/PIK3CD/PRKCA/FYN/RHOD/MAPK3/SEMA3B/MYL9	15
KEGG	hsa04910	Insulin signaling pathway	11/794	137/8135	0.7946	0.9933	0.7776	PTPN1/CBLB/LIPE/HK3/PIK3CD/PHKG1/ELK1/MAPK3/IRS1/ACACA/GRB2	11
KEGG	hsa04144	Endocytosis	21/794	251/8135	0.8044	0.9933	0.7776	PSD4/HLA-G/ACAP1/IL2RG/ACTR2/ARFGEF1/HLA-A/VPS28/SMAP2/CBLB/ARAP2/ARPC1A/USP8/CYTH2/IL2RB/CYTH4/EHD4/AMPH/EPN3/VPS37A/WASL	21
KEGG	hsa00860	Porphyrin metabolism	3/794	43/8135	0.8049	0.9933	0.7776	UROD/ALAD/BLVRB	3
KEGG	hsa04970	Salivary secretion	7/794	93/8135	0.8156	0.9933	0.7776	CD38/ADCY1/PLCB2/PRKCA/ATP1B1/ITPR3/PRKCB	7
KEGG	hsa05031	Amphetamine addiction	5/794	69/8135	0.8167	0.9933	0.7776	PPP1R1B/STX1A/GRIA2/PRKCA/PRKCB	5
KEGG	hsa04350	TGF-beta signaling pathway	7/794	94/8135	0.8241	0.9933	0.7776	TGIF2/SP1/E2F5/FST/AMH/MAPK3/BMP5	7
KEGG	hsa00450	Selenocompound metabolism	1/794	17/8135	0.8258	0.9933	0.7776	PAPSS2	1
KEGG	hsa03022	Basal transcription factors	3/794	45/8135	0.8291	0.9933	0.7776	GTF2H4/GTF2H5/GTF2F1	3
KEGG	hsa04922	Glucagon signaling pathway	8/794	107/8135	0.8326	0.9933	0.7776	PDHB/PLCB2/PHKG1/PRMT1/PFKFB1/ITPR3/PDHA1/ACACA	8
KEGG	hsa04136	Autophagy - other	2/794	32/8135	0.8338	0.9933	0.7776	ATG16L1/GABARAPL2	2
KEGG	hsa04215	Apoptosis - multiple species	2/794	32/8135	0.8338	0.9933	0.7776	BIRC3/BIRC7	2
KEGG	hsa05207	Chemical carcinogenesis - receptor activation	17/794	212/8135	0.8372	0.9933	0.7776	HSP90B1/CCND3/VDR/ADCY1/JAK2/MGST3/GNAI1/NFKB1/WNT1/PIK3CD/PRKCA/RPS6KA1/MGST2/IKBKE/MAPK3/PRKCB/GRB2	17
KEGG	hsa04152	AMPK signaling pathway	9/794	120/8135	0.8407	0.9933	0.7776	STRADB/PPARG/CD36/PPP2R5A/LIPE/PIK3CD/PFKFB1/IRS1/ACACA	9
KEGG	hsa04330	Notch signaling pathway	4/794	59/8135	0.8409	0.9933	0.7776	ATXN1/MFNG/HES1/HEYL	4
KEGG	hsa04613	Neutrophil extracellular trap formation	15/794	190/8135	0.8418	0.9933	0.7776	PLCG2/SYK/ITGAL/CYBB/NFKB1/PLCB2/RAC2/FPR3/PIK3CD/PRKCA/ACTB/AGER/FCGR3B/MAPK3/PRKCB	15
KEGG	hsa00061	Fatty acid biosynthesis	1/794	18/8135	0.8429	0.9933	0.7776	ACACA	1
KEGG	hsa00982	Drug metabolism - cytochrome P450	5/794	72/8135	0.8445	0.9933	0.7776	ADH1A/ADH1C/MGST3/MGST2/ADH1B	5
KEGG	hsa04610	Complement and coagulation cascades	6/794	85/8135	0.8494	0.9933	0.7776	CFB/CD59/C6/C2/C1QA/C1S	6
KEGG	hsa01524	Platinum drug resistance	5/794	73/8135	0.8529	0.9933	0.7776	BIRC3/MGST3/PIK3CD/MGST2/MAPK3	5
KEGG	hsa04115	p53 signaling pathway	5/794	73/8135	0.8529	0.9933	0.7776	CCND3/SIVA1/CCNB1/PERP/CDK6	5
KEGG	hsa01522	Endocrine resistance	7/794	98/8135	0.855	0.9933	0.7776	E2F2/SP1/ADCY1/PIK3CD/MMP2/MAPK3/GRB2	7
KEGG	hsa04750	Inflammatory mediator regulation of TRP channels	7/794	98/8135	0.855	0.9933	0.7776	PLCG2/ADCY1/PLCB2/PIK3CD/PRKCA/ITPR3/PRKCB	7
KEGG	hsa05210	Colorectal cancer	6/794	86/8135	0.8571	0.9933	0.7776	LEF1/RALGDS/RAC2/PIK3CD/MAPK3/GRB2	6
KEGG	hsa01210	2-Oxocarboxylic acid metabolism	1/794	19/8135	0.8582	0.9933	0.7776	IDH3B	1
KEGG	hsa00140	Steroid hormone biosynthesis	4/794	61/8135	0.8592	0.9933	0.7776	AKR1C3/CYP3A7/AKR1C2/HSD17B1	4
KEGG	hsa04217	Necroptosis	12/794	159/8135	0.8629	0.9933	0.7776	BIRC3/ZBP1/STAT1/IFNAR2/SPATA2L/JAK2/CYBB/RIPK3/TICAM2/IFNAR1/IFNA16/TRPM7	12
KEGG	hsa04213	Longevity regulating pathway - multiple species	4/794	62/8135	0.8676	0.9933	0.7776	ADCY1/CRYAB/PIK3CD/IRS1	4
KEGG	hsa01230	Biosynthesis of amino acids	5/794	75/8135	0.8687	0.9933	0.7776	CBS/SHMT2/ALDH18A1/IDH3B/SDS	5
KEGG	hsa04261	Adrenergic signaling in cardiomyocytes	11/794	150/8135	0.878	0.9933	0.7776	PIK3CG/ATP2A3/ADCY1/GNAI1/PLCB2/TPM1/PPP2R5A/PRKCA/ATP1B1/MAPK3/PPP1R1A	11
KEGG	hsa04211	Longevity regulating pathway	6/794	89/8135	0.8782	0.9933	0.7776	ADCY1/PPARG/NFKB1/PIK3CD/EHMT1/IRS1	6
KEGG	hsa04976	Bile secretion	6/794	89/8135	0.8782	0.9933	0.7776	ADCY1/ABCC3/ATP1B1/KCNN2/SLC22A7/ABCC4	6
KEGG	hsa04371	Apelin signaling pathway	10/794	139/8135	0.8832	0.9933	0.7776	PIK3CG/ADCY1/MAP1LC3B/GNG11/MYLK4/GNAI1/PLCB2/LIPE/ITPR3/MAPK3	10
KEGG	hsa05418	Fluid shear stress and atherosclerosis	10/794	139/8135	0.8832	0.9933	0.7776	HSP90B1/NQO1/IKBKG/MGST3/NFKB1/RAC2/PIK3CD/ACTB/MGST2/MMP2	10
KEGG	hsa00770	Pantothenate and CoA biosynthesis	1/794	21/8135	0.8846	0.9933	0.7776	PPCS	1
KEGG	hsa00230	Purine metabolism	9/794	128/8135	0.8891	0.9947	0.7788	ADCY1/ENTPD1/PGM1/PAPSS2/NME4/HDDC2/NUDT2/ADA/IMPDH2	9
KEGG	hsa00983	Drug metabolism - other enzymes	5/794	80/8135	0.9019	1	0.7829	MGST3/NME4/TYMP/MGST2/IMPDH2	5
KEGG	hsa04614	Renin-angiotensin system	1/794	23/8135	0.9061	1	0.7829	ANPEP	1
KEGG	hsa04728	Dopaminergic synapse	9/794	132/8135	0.9083	1	0.7829	PPP1R1B/GRIA2/GNG11/GNAI1/PLCB2/PPP2R5A/PRKCA/ITPR3/PRKCB	9
KEGG	hsa05204	Chemical carcinogenesis - DNA adducts	4/794	69/8135	0.9154	1	0.7829	MGST3/CYP3A7/MGST2/AKR1C2	4
KEGG	hsa03440	Homologous recombination	2/794	41/8135	0.9199	1	0.7829	TOPBP1/SSBP1	2
KEGG	hsa00564	Glycerophospholipid metabolism	6/794	98/8135	0.9263	1	0.7829	PLA2G2A/DGKQ/GPD1/PNPLA6/AGPAT2/GPAM	6
KEGG	hsa05218	Melanoma	4/794	72/8135	0.9307	1	0.7829	E2F2/PIK3CD/MAPK3/CDK6	4
KEGG	hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	1/794	27/8135	0.9378	1	0.7829	B4GALT4	1
KEGG	hsa04140	Autophagy - animal	9/794	141/8135	0.9414	1	0.7829	ATG16L1/MAP1LC3B/RRAGA/GABARAPL2/PIK3CD/VAMP8/MAPK3/IRS1/RRAGD	9
KEGG	hsa04914	Progesterone-mediated oocyte maturation	6/794	102/8135	0.9417	1	0.7829	ADCY1/CCNB1/GNAI1/PIK3CD/RPS6KA1/MAPK3	6
KEGG	hsa00591	Linoleic acid metabolism	1/794	29/8135	0.9494	1	0.7829	PLA2G2A	1
KEGG	hsa04114	Oocyte meiosis	8/794	131/8135	0.9498	1	0.7829	ADCY1/CDC20/YWHAH/CCNB1/PPP2R5A/RPS6KA1/ITPR3/MAPK3	8
KEGG	hsa05032	Morphine addiction	5/794	91/8135	0.9504	1	0.7829	ADCY1/GNG11/GNAI1/PRKCA/PRKCB	5
KEGG	hsa00053	Ascorbate and aldarate metabolism	1/794	30/8135	0.9544	1	0.7829	ALDH7A1	1
KEGG	hsa04710	Circadian rhythm	1/794	31/8135	0.9588	1	0.7829	PER3	1
KEGG	hsa05226	Gastric cancer	9/794	149/8135	0.9616	1	0.7829	E2F2/LEF1/WNT11/FZD5/WNT1/PIK3CD/FZD2/MAPK3/GRB2	9
KEGG	hsa03008	Ribosome biogenesis in eukaryotes	6/794	109/8135	0.9619	1	0.7829	POP5/POP7/SNORD3C/NHP2/GNL3L/SNORD3A	6
KEGG	hsa04979	Cholesterol metabolism	2/794	50/8135	0.9627	1	0.7829	CD36/LPL	2
KEGG	hsa04020	Calcium signaling pathway	16/794	240/8135	0.9656	1	0.7829	CD38/PLCG2/ATP2A3/ADCY1/VEGFB/CAMK1G/ADORA2A/MCOLN2/MYLK4/PLCB2/PRKCA/PHKG1/GNA15/ITPR3/RET/PRKCB	16
KEGG	hsa00040	Pentose and glucuronate interconversions	1/794	34/8135	0.9698	1	0.7829	DCXR	1
KEGG	hsa04924	Renin secretion	3/794	69/8135	0.9704	1	0.7829	GNAI1/PLCB2/ITPR3	3
KEGG	hsa05206	MicroRNAs in cancer	21/794	310/8135	0.9762	1	0.7829	EZR/SLC7A1/E2F2/PLCG2/MIR126/ITGA5/SPRY2/BCL2L2/NFKB1/TPM1/FOXP1/PIK3CD/PRKCA/MIR101-1/MAPK3/EZH2/PRKCB/CDK6/IRS1/MIR206/GRB2	21
KEGG	hsa03040	Spliceosome	8/794	147/8135	0.9799	1	0.7829	PRPF40A/PUF60/RNU4-1/RNU4-2/SNRPC/LSM3/PCBP1/DHX8	8
KEGG	hsa05033	Nicotine addiction	1/794	40/8135	0.9837	1	0.7829	GRIA2	1
KEGG	hsa03013	Nucleocytoplasmic transport	5/794	108/8135	0.9842	1	0.7829	SAP18/XPO5/POM121L2/THOC7/NUP210	5
KEGG	hsa04142	Lysosome	6/794	132/8135	0.9916	1	0.7829	AP1G2/LAMP3/LAPTM5/ACP2/DNASE2/SLC17A5	6
KEGG	hsa04742	Taste transduction	3/794	86/8135	0.9925	1	0.7829	SCN9A/PLCB2/ITPR3	3
KEGG	hsa00565	Ether lipid metabolism	1/794	49/8135	0.9936	1	0.7829	PLA2G2A	1
KEGG	hsa00600	Sphingolipid metabolism	1/794	52/8135	0.9953	1	0.7829	UGCG	1
KEGG	hsa03460	Fanconi anemia pathway	1/794	54/8135	0.9962	1	0.7829	HES1	1
KEGG	hsa04721	Synaptic vesicle cycle	2/794	78/8135	0.997	1	0.7829	STX1A/SLC6A1	2
KEGG	hsa05034	Alcoholism	6/794	187/8135	0.9999	1	0.7829	PPP1R1B/ADORA2A/GNG11/GNAI1/MAPK3/GRB2	6
KEGG	hsa04080	Neuroactive ligand-receptor interaction	15/794	353/8135	1	1	0.7829	GZMA/ADRA2A/GRIA2/LPAR2/ADORA2A/THRA/VIPR1/FPR3/CHRNA1/PENK/POMC/S1PR3/S1PR4/KISS1R/P2RY8	15
KEGG	hsa04740	Olfactory transduction	5/794	440/8135	1	1	0.7829	OR9I1/OR7G1/OR52N1/OR2B6/OR2M4	5