ONTOLOGY	ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	qvalue	geneID	Count
KEGG	hsa04110	Cell cycle	27/411	126/8135	9.705e-11	3.018e-08	2.891e-08	CHEK1/BUB1/E2F2/PLK1/BUB1B/CDC20/PKMYT1/CDC25A/TTK/MCM4/SKP2/CCNB1/CCNA2/CCNB2/MCM3/MAD2L1/CCNE1/PTTG1/MCM7/CCNE2/YWHAQ/MCM2/CDC23/BUB3/HDAC1/E2F1/MCM5	27
KEGG	hsa03030	DNA replication	13/411	36/8135	9.237e-09	1.436e-06	1.376e-06	RFC4/MCM4/RNASEH2A/MCM3/LIG1/POLE2/MCM7/POLA2/RFC5/FEN1/MCM2/POLE/MCM5	13
KEGG	hsa05166	Human T-cell leukemia virus 1 infection	25/411	222/8135	0.0001318	0.01367	0.01309	CHEK1/E2F2/PIK3CD/BUB1B/CDC20/CALR/CCNA2/CCNB2/MAD2L1/CCNE1/LCK/PTTG1/PPP3CA/MAP2K4/IL15/IL2RA/CCNE2/CRTC2/CD3E/CDC23/ELK1/BUB3/E2F1/ITGAL/MAPK9	25
KEGG	hsa05162	Measles	18/411	139/8135	0.0002066	0.01607	0.01539	PIK3CD/IRF7/CCNE1/TP73/IFNAR1/IL2RA/CCNE2/TRAF3/SLAMF1/CD3E/CD28/CD46/IL1A/STAT2/TLR9/FASLG/MAPK9/HSPA1L	18
KEGG	hsa05340	Primary immunodeficiency	8/411	38/8135	0.0005082	0.02539	0.02432	ADA/LCK/RFXANK/AICDA/RFXAP/CD3E/UNG/BLNK	8
KEGG	hsa05169	Epstein-Barr virus infection	22/411	202/8135	0.0005284	0.02539	0.02432	E2F2/PIK3CD/BCL2L11/IRF7/SKP2/CALR/CCNA2/CCNE1/IFNAR1/MAP2K4/PSMC3/CCNE2/TRAF3/CD3E/USP7/HDAC1/TRAF2/E2F1/ITGAL/STAT2/BLNK/MAPK9	22
KEGG	hsa04914	Progesterone-mediated oocyte maturation	14/411	102/8135	0.0005714	0.02539	0.02432	BUB1/PIK3CD/PLK1/PKMYT1/CDC25A/CCNB1/CCNA2/CCNB2/MAD2L1/ARAF/RPS6KA1/IGF1R/CDC23/MAPK9	14
KEGG	hsa04114	Oocyte meiosis	16/411	131/8135	0.000884	0.03437	0.03292	BUB1/PLK1/CDC20/PKMYT1/CCNB1/CCNB2/MAD2L1/CCNE1/PTTG1/PPP3CA/CCNE2/RPS6KA1/FBXO5/YWHAQ/IGF1R/CDC23	16
KEGG	hsa03410	Base excision repair	7/411	33/8135	0.001086	0.03754	0.03596	LIG1/POLE2/PARP1/FEN1/POLE/UNG/NEIL3	7
KEGG	hsa04218	Cellular senescence	17/411	156/8135	0.002202	0.06848	0.0656	CHEK1/E2F2/PIK3CD/CDC25A/CCNB1/CCNA2/CCNB2/CCNE1/FOXM1/PPP3CA/LIN9/CCNE2/HIPK2/CAPN1/CAPN2/E2F1/IL1A	17
KEGG	hsa05161	Hepatitis B	17/411	162/8135	0.003282	0.09279	0.08888	E2F2/PIK3CD/IRF7/CCNA2/CCNE1/ARAF/IFNAR1/MAP2K4/TLR3/CCNE2/TRAF3/YWHAQ/ELK1/E2F1/STAT2/FASLG/MAPK9	17
KEGG	hsa05226	Gastric cancer	15/411	149/8135	0.00815	0.2112	0.2023	E2F2/PIK3CD/RARB/FGF17/CDH1/CCNE1/ARAF/FZD2/TCF7L2/CCNE2/FZD7/CTNNA1/FGF23/LEF1/E2F1	15
KEGG	hsa04520	Adherens junction	9/411	71/8135	0.009066	0.2169	0.2077	CDH1/ACP1/TCF7L2/PTPRM/CTNNA1/IGF1R/LEF1/TJP1/CTNND1	9
KEGG	hsa04115	p53 signaling pathway	9/411	73/8135	0.01082	0.2403	0.2302	CHEK1/SESN3/GTSE1/COP1/CCNB1/CCNB2/CCNE1/TP73/CCNE2	9
KEGG	hsa00270	Cysteine and methionine metabolism	7/411	51/8135	0.0135	0.2799	0.2681	CBS/AHCY/CDO1/GOT1/DNMT1/AHCYL1/LDHAL6A	7
KEGG	hsa04068	FoxO signaling pathway	13/411	131/8135	0.01484	0.2885	0.2763	PIK3CD/PLK1/BCL2L11/PLK4/SKP2/CCNB1/CCNB2/ARAF/USP7/IGF1R/GABARAPL1/FASLG/MAPK9	13
KEGG	hsa05222	Small cell lung cancer	10/411	92/8135	0.01727	0.316	0.3026	E2F2/PIK3CD/RARB/SKP2/CCNE1/CCNE2/TRAF3/TRAF2/E2F1/CKS2	10
KEGG	hsa05221	Acute myeloid leukemia	8/411	67/8135	0.01898	0.3279	0.3141	PIK3CD/CCNA2/ARAF/TCF7L2/PIM1/PIM2/MPO/LEF1	8
KEGG	hsa04530	Tight junction	15/411	169/8135	0.02368	0.3583	0.3432	CGN/ARHGEF18/CLDN4/RAB8A/ARPC5L/RAPGEF6/HCLS1/ARHGEF2/ROCK2/PRKCZ/TJP3/ARPC3/TJP1/CGNL1/MAPK9	15
KEGG	hsa05215	Prostate cancer	10/411	97/8135	0.02415	0.3583	0.3432	E2F2/PIK3CD/CCNE1/ARAF/TCF7L2/CCNE2/HSP90B1/IGF1R/LEF1/E2F1	10
KEGG	hsa04668	TNF signaling pathway	11/411	112/8135	0.02562	0.3583	0.3432	PIK3CD/CX3CL1/EDN1/MAP2K4/IL15/TRAF3/ITCH/TRAF2/RIPK3/TNFRSF1B/MAPK9	11
KEGG	hsa05213	Endometrial cancer	7/411	58/8135	0.02598	0.3583	0.3432	PIK3CD/CDH1/ARAF/TCF7L2/CTNNA1/ELK1/LEF1	7
KEGG	hsa03430	Mismatch repair	4/411	23/8135	0.0265	0.3583	0.3432	RFC4/LIG1/EXO1/RFC5	4
KEGG	hsa05218	Melanoma	8/411	72/8135	0.02804	0.3634	0.3481	E2F2/PIK3CD/FGF17/CDH1/ARAF/IGF1R/FGF23/E2F1	8
KEGG	hsa04918	Thyroid hormone synthesis	8/411	75/8135	0.03473	0.432	0.4138	PDIA4/ASGR2/GPX3/TSHR/HSP90B1/ATP1A3/ASGR1/GPX2	8
KEGG	hsa05130	Pathogenic Escherichia coli infection	16/411	197/8135	0.04078	0.4875	0.4669	CLDN4/TMED10/ARPC5L/MYO6/NCKAP1/HCLS1/ARHGEF1/ARHGEF2/ROCK2/MYO1C/ARPC3/TJP1/TRAF2/F2R/FASLG/MAPK9	16
KEGG	hsa00330	Arginine and proline metabolism	6/411	51/8135	0.04232	0.4875	0.4669	P4HA3/CNDP2/OAT/ODC1/SMOX/GOT1	6
KEGG	hsa04810	Regulation of actin cytoskeleton	17/411	218/8135	0.04933	0.5479	0.5249	PIK3CD/FGD3/FGF17/ITGB6/ARPC5L/PIP5K1A/ARAF/NCKAP1/ARHGEF1/ROCK2/PFN2/FGF23/ARPC3/DIAPH2/F2R/ITGAL/GSN	17
KEGG	hsa04390	Hippo signaling pathway	13/411	157/8135	0.05395	0.5592	0.5357	SOX2/CDH1/FZD2/TP73/BMPR1A/TCF7L2/LATS1/FZD7/YWHAQ/CTNNA1/PRKCZ/LEF1/SAV1	13
KEGG	hsa05160	Hepatitis C	13/411	157/8135	0.05395	0.5592	0.5357	E2F2/PIK3CD/CLDN4/IRF7/ARAF/IFNAR1/TLR3/TRAF3/YWHAQ/TRAF2/E2F1/STAT2/FASLG	13
KEGG	hsa05167	Kaposi sarcoma-associated herpesvirus infection	15/411	194/8135	0.06597	0.6433	0.6162	E2F2/PIK3CD/IRF7/PPP3CA/IFNAR1/MAP2K4/TCF7L2/TLR3/TRAF3/GNGT2/LEF1/TRAF2/E2F1/STAT2/MAPK9	15
KEGG	hsa05224	Breast cancer	12/411	147/8135	0.06801	0.6433	0.6162	E2F2/PIK3CD/FGF17/ARAF/FZD2/TCF7L2/FZD7/IGF1R/FGF23/LEF1/E2F1/HEYL	12
KEGG	hsa00480	Glutathione metabolism	6/411	58/8135	0.07117	0.6433	0.6162	GSTM3/IDH2/GPX3/ODC1/GPX2/CHAC1	6
KEGG	hsa04620	Toll-like receptor signaling pathway	9/411	104/8135	0.07929	0.6433	0.6162	PIK3CD/IRF7/IFNAR1/MAP2K4/TLR3/TRAF3/LBP/TLR9/MAPK9	9
KEGG	hsa04660	T cell receptor signaling pathway	9/411	104/8135	0.07929	0.6433	0.6162	PIK3CD/LCK/PPP3CA/GRAP2/CD3E/PDCD1/CD28/MAPK9/CARD11	9
KEGG	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	8/411	89/8135	0.07983	0.6433	0.6162	PIK3CD/BATF/LCK/PPP3CA/CD3E/PDCD1/CD28/TLR9	8
KEGG	hsa04210	Apoptosis	11/411	136/8135	0.08243	0.6433	0.6162	PIK3CD/CASP2/BCL2L11/PARP1/LMNB2/CAPN1/TRAF2/CAPN2/CTSZ/FASLG/MAPK9	11
KEGG	hsa05225	Hepatocellular carcinoma	13/411	168/8135	0.08253	0.6433	0.6162	GSTM3/E2F2/PIK3CD/ARAF/FZD2/SMARCD1/TCF7L2/SMARCB1/FZD7/IGF1R/ELK1/LEF1/E2F1	13
KEGG	hsa05135	Yersinia infection	11/411	137/8135	0.08579	0.6433	0.6162	PIK3CD/ARPC5L/LCK/PIP5K1A/MAP2K4/ARHGEF1/RPS6KA1/ROCK2/ARPC3/TRAF2/MAPK9	11
KEGG	hsa00140	Steroid hormone biosynthesis	6/411	61/8135	0.0863	0.6433	0.6162	UGT2B7/UGT2B17/HSD17B1/CYP11A1/CYP11B2/HSD3B1	6
KEGG	hsa00770	Pantothenate and CoA biosynthesis	3/411	21/8135	0.08675	0.6433	0.6162	PANK2/COASY/ENPP1	3
KEGG	hsa03420	Nucleotide excision repair	5/411	47/8135	0.08687	0.6433	0.6162	RFC4/LIG1/POLE2/RFC5/POLE	5
KEGG	hsa03020	RNA polymerase	4/411	34/8135	0.09033	0.6478	0.6205	CD3EAP/POLR1B/POLR2D/POLR2A	4
KEGG	hsa05418	Fluid shear stress and atherosclerosis	11/411	139/8135	0.09276	0.6478	0.6205	GSTM3/PIK3CD/EDN1/BMPR1A/MAP2K4/ARHGEF2/HSP90B1/PRKCZ/IL1A/DUSP1/MAPK9	11
KEGG	hsa04659	Th17 cell differentiation	9/411	108/8135	0.09506	0.6478	0.6205	LCK/PPP3CA/IL2RA/IL27RA/RORC/CD3E/GATA3/IL23A/MAPK9	9
KEGG	hsa00900	Terpenoid backbone biosynthesis	3/411	22/8135	0.09686	0.6478	0.6205	PDSS2/PCYOX1/PMVK	3
KEGG	hsa04672	Intestinal immune network for IgA production	5/411	49/8135	0.0997	0.6478	0.6205	CCR10/AICDA/IL15/CD28/CCL25	5
KEGG	hsa03018	RNA degradation	7/411	79/8135	0.1033	0.6478	0.6205	LSM2/PNLDC1/EXOSC3/PNPT1/CNOT3/LSM4/DCPS	7
KEGG	hsa00760	Nicotinate and nicotinamide metabolism	4/411	36/8135	0.1062	0.6478	0.6205	NNMT/ENPP1/SIRT7/NT5E	4
KEGG	hsa04217	Necroptosis	12/411	159/8135	0.1065	0.6478	0.6205	PARP1/IFNAR1/TLR3/CHMP7/CAPN1/TRAF2/CAPN2/IL1A/RIPK3/STAT2/FASLG/MAPK9	12
KEGG	hsa04614	Renin-angiotensin system	3/411	23/8135	0.1074	0.6478	0.6205	LNPEP/KLK2/PREP	3
KEGG	hsa04015	Rap1 signaling pathway	15/411	210/8135	0.1105	0.6478	0.6205	PIK3CD/SIPA1/FGF17/CDH1/RAPGEF6/ADORA2A/IGF1R/PFN2/FGF23/PRKCZ/CTNND1/F2R/ITGAL/PRKD2/RGS14	15
KEGG	hsa00230	Purine metabolism	10/411	128/8135	0.1125	0.6478	0.6205	ADA/NME1/PDE3A/PDE6G/PDE4C/AK1/ENPP1/PFAS/NUDT5/NT5E	10
KEGG	hsa04380	Osteoclast differentiation	10/411	128/8135	0.1125	0.6478	0.6205	SIRPB1/PIK3CD/LCK/PPP3CA/IFNAR1/TRAF2/IL1A/STAT2/BLNK/MAPK9	10
KEGG	hsa00600	Sphingolipid metabolism	5/411	52/8135	0.1206	0.682	0.6533	SPHK2/SGPL1/CERK/DEGS1/NEU1	5
KEGG	hsa05132	Salmonella infection	17/411	249/8135	0.1266	0.703	0.6733	PIK3CD/CSE1L/ARPC5L/MYO6/NCKAP1/MAP2K4/TCF7L2/KLC2/HSP90B1/ROCK2/PFN2/LEF1/ARPC3/TRAF2/RIPK3/TLR9/MAPK9	17
KEGG	hsa04144	Endocytosis	17/411	251/8135	0.1332	0.7228	0.6924	RAB8A/ARPC5L/PIP5K1A/VPS37B/PSD/EHD3/PSD4/VPS26B/IL2RA/CHMP7/IGF1R/AP2S1/STAMBP/ITCH/PRKCZ/ARPC3/HSPA1L	17
KEGG	hsa03460	Fanconi anemia pathway	5/411	54/8135	0.1356	0.7228	0.6924	UBE2T/RAD51/FANCE/FANCD2/BLM	5
KEGG	hsa01232	Nucleotide metabolism	7/411	85/8135	0.1371	0.7228	0.6924	TYMS/ADA/NME1/TK1/AK1/ENPP1/NT5E	7
KEGG	hsa05203	Viral carcinogenesis	14/411	204/8135	0.1505	0.7566	0.7247	CHEK1/PIK3CD/CDC20/IRF7/SKP2/CCNA2/CCNE1/CCNE2/TRAF3/YWHAQ/USP7/HDAC1/TRAF2/GSN	14
KEGG	hsa03440	Homologous recombination	4/411	41/8135	0.1509	0.7566	0.7247	RAD54L/RAD51/XRCC3/BLM	4
KEGG	hsa05219	Bladder cancer	4/411	41/8135	0.1509	0.7566	0.7247	E2F2/CDH1/ARAF/E2F1	4
KEGG	hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	2/411	14/8135	0.1555	0.7566	0.7247	B4GALT3/ST3GAL2	2
KEGG	hsa04141	Protein processing in endoplasmic reticulum	12/411	171/8135	0.1557	0.7566	0.7247	DNAJB11/SEC61A1/CALR/PDIA4/DNAJC3/HSP90B1/CAPN1/TRAF2/CAPN2/STT3A/MAPK9/HSPA1L	12
KEGG	hsa00562	Inositol phosphate metabolism	6/411	73/8135	0.1624	0.7771	0.7444	PIK3CD/MTMR1/PIP5K1A/INPP5D/IMPA1/MTMR4	6
KEGG	hsa00240	Pyrimidine metabolism	5/411	58/8135	0.1679	0.791	0.7577	TYMS/NME1/TK1/ENPP1/NT5E	5
KEGG	hsa00730	Thiamine metabolism	2/411	15/8135	0.1737	0.8062	0.7722	ACP1/AK1	2
KEGG	hsa04392	Hippo signaling pathway - multiple species	3/411	29/8135	0.1786	0.8097	0.7756	LATS1/SAV1/RASSF4	3
KEGG	hsa04120	Ubiquitin mediated proteolysis	10/411	142/8135	0.1807	0.8097	0.7756	SAE1/COP1/CDC20/SKP2/VHL/UBE2U/UBE2B/CDC23/ITCH/UBE2C	10
KEGG	hsa05170	Human immunodeficiency virus 1 infection	14/411	212/8135	0.1847	0.8097	0.7756	CHEK1/PIK3CD/CALR/CCNB1/CCNB2/PPP3CA/APOBEC3C/CD3E/GNGT2/TRAF2/TNFRSF1B/AP1G2/FASLG/MAPK9	14
KEGG	hsa05212	Pancreatic cancer	6/411	76/8135	0.1849	0.8097	0.7756	E2F2/PIK3CD/ARAF/RAD51/E2F1/MAPK9	6
KEGG	hsa01523	Antifolate resistance	3/411	30/8135	0.1916	0.8097	0.7756	TYMS/GGH/SLC19A1	3
KEGG	hsa05100	Bacterial invasion of epithelial cells	6/411	77/8135	0.1927	0.8097	0.7756	PIK3CD/CDH1/ARPC5L/HCLS1/CTNNA1/ARPC3	6
KEGG	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	6/411	77/8135	0.1927	0.8097	0.7756	ITGB6/TCF7L2/CTNNA1/ATP2A3/LEF1/SLC8A1	6
KEGG	hsa05417	Lipid and atherosclerosis	14/411	215/8135	0.1984	0.8226	0.7879	PIK3CD/IRF7/PPP3CA/MAP2K4/ARHGEF1/TRAF3/LBP/HSP90B1/ROCK2/TRAF2/AGER/FASLG/MAPK9/HSPA1L	14
KEGG	hsa03050	Proteasome	4/411	46/8135	0.2014	0.8243	0.7896	PSMC3/PSMB3/PSMF1/PSME2	4
KEGG	hsa00983	Drug metabolism - other enzymes	6/411	80/8135	0.2166	0.8485	0.8128	GSTM3/UGT2B7/UGT2B17/NME1/TK1/MPO	6
KEGG	hsa04670	Leukocyte transendothelial migration	8/411	114/8135	0.2181	0.8485	0.8128	PIK3CD/SIPA1/CLDN4/CTNNA1/ROCK2/ARHGAP5/CTNND1/ITGAL	8
KEGG	hsa04070	Phosphatidylinositol signaling system	7/411	97/8135	0.2183	0.8485	0.8128	PIK3CD/DGKE/MTMR1/PIP5K1A/INPP5D/IMPA1/MTMR4	7
KEGG	hsa04666	Fc gamma R-mediated phagocytosis	7/411	97/8135	0.2183	0.8485	0.8128	PIK3CD/SPHK2/ARPC5L/PIP5K1A/INPP5D/ARPC3/GSN	7
KEGG	hsa00051	Fructose and mannose metabolism	3/411	33/8135	0.2316	0.8798	0.8427	TSTA3/KHK/ALDOB	3
KEGG	hsa04933	AGE-RAGE signaling pathway in diabetic complications	7/411	100/8135	0.2409	0.8798	0.8427	PIK3CD/EDN1/PIM1/PRKCZ/IL1A/AGER/MAPK9	7
KEGG	hsa05110	Vibrio cholerae infection	4/411	50/8135	0.2449	0.8798	0.8427	SEC61A1/PDIA4/TJP1/KDELR2	4
KEGG	hsa05144	Malaria	4/411	50/8135	0.2449	0.8798	0.8427	KLRK1/ITGAL/TLR9/KLRB1	4
KEGG	hsa01240	Biosynthesis of cofactors	10/411	153/8135	0.2449	0.8798	0.8427	UGT2B7/UGT2B17/GGH/NME1/PANK2/COASY/AK1/LIPT1/FLAD1/PNPO	10
KEGG	hsa01210	2-Oxocarboxylic acid metabolism	2/411	19/8135	0.249	0.8798	0.8427	IDH2/GOT1	2
KEGG	hsa04071	Sphingolipid signaling pathway	8/411	119/8135	0.253	0.8798	0.8427	PIK3CD/SPHK2/SGPL1/DEGS1/ROCK2/PRKCZ/TRAF2/MAPK9	8
KEGG	hsa04913	Ovarian steroidogenesis	4/411	51/8135	0.2561	0.8798	0.8427	HSD17B1/CYP11A1/IGF1R/HSD3B1	4
KEGG	hsa05142	Chagas disease	7/411	102/8135	0.2563	0.8798	0.8427	PIK3CD/CALR/MAP2K4/CD3E/TLR9/FASLG/MAPK9	7
KEGG	hsa04932	Non-alcoholic fatty liver disease	10/411	155/8135	0.2574	0.8798	0.8427	PIK3CD/BCL2L11/COX7A1/ITCH/COX5A/TRAF2/NDUFS6/IL1A/FASLG/MAPK9	10
KEGG	hsa04934	Cushing syndrome	10/411	155/8135	0.2574	0.8798	0.8427	E2F2/CCNE1/FZD2/CYP11A1/TCF7L2/CCNE2/FZD7/LEF1/E2F1/HSD3B1	10
KEGG	hsa05210	Colorectal cancer	6/411	86/8135	0.2673	0.8965	0.8587	PIK3CD/BCL2L11/ARAF/TCF7L2/LEF1/MAPK9	6
KEGG	hsa00100	Steroid biosynthesis	2/411	20/8135	0.2681	0.8965	0.8587	EBP/LBR	2
KEGG	hsa04064	NF-kappa B signaling pathway	7/411	104/8135	0.272	0.9001	0.8621	LCK/PARP1/TRAF3/LBP/TRAF2/BLNK/CARD11	7
KEGG	hsa04961	Endocrine and other factor-regulated calcium reabsorption	4/411	53/8135	0.2788	0.9127	0.8743	AP2S1/ATP1A3/KLK2/SLC8A1	4
KEGG	hsa05216	Thyroid cancer	3/411	37/8135	0.2869	0.9294	0.8903	CDH1/TCF7L2/LEF1	3
KEGG	hsa04550	Signaling pathways regulating pluripotency of stem cells	9/411	143/8135	0.2969	0.9362	0.8967	PIK3CD/SOX2/PCGF2/INHBA/FZD2/BMPR1A/LHX5/FZD7/IGF1R	9
KEGG	hsa04137	Mitophagy - animal	5/411	72/8135	0.2985	0.9362	0.8967	BCL2L13/GABARAPL1/E2F1/MAPK9/PINK1	5
KEGG	hsa05223	Non-small cell lung cancer	5/411	72/8135	0.2985	0.9362	0.8967	E2F2/PIK3CD/RARB/ARAF/E2F1	5
KEGG	hsa05152	Tuberculosis	11/411	180/8135	0.301	0.9362	0.8967	SPHK2/RFXANK/PPP3CA/RFXAP/CORO1A/LBP/IL1A/CARD9/IL23A/TLR9/MAPK9	11
KEGG	hsa03013	Nucleocytoplasmic transport	7/411	108/8135	0.3042	0.9368	0.8973	CSE1L/NUP37/RANGAP1/SEH1L/NUP50/IPO11/DDX19A	7
KEGG	hsa05165	Human papillomavirus infection	19/411	331/8135	0.3145	0.9388	0.8993	PIK3CD/ITGB6/CCNA2/CCNE1/FZD2/IFNAR1/MFNG/TCF7L2/TLR3/CCNE2/TRAF3/FZD7/PRKCZ/HDAC1/TUBG1/E2F1/HEYL/STAT2/FASLG	19
KEGG	hsa04658	Th1 and Th2 cell differentiation	6/411	92/8135	0.3205	0.9388	0.8993	LCK/PPP3CA/IL2RA/CD3E/GATA3/MAPK9	6
KEGG	hsa04060	Cytokine-cytokine receptor interaction	17/411	295/8135	0.3218	0.9388	0.8993	GDF9/INHBA/IL16/CX3CL1/TNFRSF8/BMPR1A/IFNAR1/CCR10/IL15/IL2RA/IL27RA/IL1A/TNFRSF1B/CCL25/TNFRSF14/IL23A/FASLG	17
KEGG	hsa03040	Spliceosome	9/411	147/8135	0.3251	0.9388	0.8993	SNRPC/U2AF1L4/LSM2/SNRPG/SNRPF/LSM4/EFTUD2/PPIH/HSPA1L	9
KEGG	hsa03060	Protein export	2/411	23/8135	0.3251	0.9388	0.8993	SEC61A1/SRP68	2
KEGG	hsa04964	Proximal tubule bicarbonate reclamation	2/411	23/8135	0.3251	0.9388	0.8993	AQP1/ATP1A3	2
KEGG	hsa05214	Glioma	5/411	75/8135	0.3287	0.9388	0.8993	E2F2/PIK3CD/ARAF/IGF1R/E2F1	5
KEGG	hsa00260	Glycine, serine and threonine metabolism	3/411	40/8135	0.329	0.9388	0.8993	GLDC/CBS/GLYCTK	3
KEGG	hsa05220	Chronic myeloid leukemia	5/411	76/8135	0.3388	0.9579	0.9176	E2F2/PIK3CD/ARAF/HDAC1/E2F1	5
KEGG	hsa04650	Natural killer cell mediated cytotoxicity	8/411	131/8135	0.3426	0.9599	0.9194	PIK3CD/KLRK1/LCK/ARAF/PPP3CA/IFNAR1/ITGAL/FASLG	8
KEGG	hsa05163	Human cytomegalovirus infection	13/411	225/8135	0.3491	0.9694	0.9285	E2F2/PIK3CD/CX3CL1/CALR/PPP3CA/AKAP13/ARHGEF1/ROCK2/GNGT2/ELK1/TRAF2/E2F1/FASLG	13
KEGG	hsa05332	Graft-versus-host disease	3/411	42/8135	0.3571	0.9797	0.9385	CD28/IL1A/FASLG	3
KEGG	hsa04612	Antigen processing and presentation	5/411	78/8135	0.3591	0.9797	0.9385	CALR/RFXANK/RFXAP/PSME2/HSPA1L	5
KEGG	hsa04940	Type I diabetes mellitus	3/411	43/8135	0.3711	0.9923	0.9505	CD28/IL1A/FASLG	3
KEGG	hsa01522	Endocrine resistance	6/411	98/8135	0.3751	0.9923	0.9505	E2F2/PIK3CD/ARAF/IGF1R/E2F1/MAPK9	6
KEGG	hsa04213	Longevity regulating pathway - multiple species	4/411	62/8135	0.3832	0.9923	0.9505	PIK3CD/IGF1R/HDAC1/HSPA1L	4
KEGG	hsa04150	mTOR signaling pathway	9/411	156/8135	0.3902	0.9923	0.9505	PIK3CD/SKP2/RRAGA/TBC1D7/FZD2/SEH1L/RPS6KA1/FZD7/IGF1R	9
KEGG	hsa04061	Viral protein interaction with cytokine and cytokine receptor	6/411	100/8135	0.3934	0.9923	0.9505	CX3CL1/CCR10/IL2RA/TNFRSF1B/CCL25/TNFRSF14	6
KEGG	hsa00310	Lysine degradation	4/411	63/8135	0.3948	0.9923	0.9505	GCDH/EZH2/PRDM9/SUV39H1	4
KEGG	hsa05217	Basal cell carcinoma	4/411	63/8135	0.3948	0.9923	0.9505	FZD2/TCF7L2/FZD7/LEF1	4
KEGG	hsa04662	B cell receptor signaling pathway	5/411	82/8135	0.3998	0.9923	0.9505	PIK3CD/PPP3CA/INPP5D/BLNK/CARD11	5
KEGG	hsa04930	Type II diabetes mellitus	3/411	46/8135	0.4127	0.9923	0.9505	PIK3CD/PRKCZ/MAPK9	3
KEGG	hsa04010	MAPK signaling pathway	16/411	294/8135	0.4161	0.9923	0.9505	FGF17/ARAF/PPP3CA/MAP2K4/PTPN7/RPS6KA1/IGF1R/FGF23/ELK1/TRAF2/IL1A/MAP4K1/DUSP1/FASLG/MAPK9/HSPA1L	16
KEGG	hsa05321	Inflammatory bowel disease	4/411	65/8135	0.4179	0.9923	0.9505	RORC/GATA3/IL1A/IL23A	4
KEGG	hsa00514	Other types of O-glycan biosynthesis	3/411	47/8135	0.4264	0.9923	0.9505	B4GALT3/MFNG/GALNT11	3
KEGG	hsa04625	C-type lectin receptor signaling pathway	6/411	104/8135	0.4299	0.9923	0.9505	PIK3CD/PPP3CA/STAT2/CARD9/IL23A/MAPK9	6
KEGG	hsa04012	ErbB signaling pathway	5/411	85/8135	0.4302	0.9923	0.9505	PIK3CD/ARAF/MAP2K4/ELK1/MAPK9	5
KEGG	hsa04360	Axon guidance	10/411	182/8135	0.4391	0.9923	0.9505	PIK3CD/RYK/SEMA5A/PPP3CA/DPYSL2/EPHA1/ROCK2/BOC/PRKCZ/SLIT1	10
KEGG	hsa04024	cAMP signaling pathway	12/411	221/8135	0.4412	0.9923	0.9505	PIK3CD/PDE3A/EDN1/PDE4C/TSHR/ADORA2A/ROCK2/ATP1A3/ATP2A3/CNGA4/F2R/MAPK9	12
KEGG	hsa04928	Parathyroid hormone synthesis, secretion and action	6/411	106/8135	0.4481	0.9923	0.9505	ARAF/AKAP13/PDE4C/ARHGEF1/FGF23/GATA3	6
KEGG	hsa04260	Cardiac muscle contraction	5/411	87/8135	0.4503	0.9923	0.9505	COX7A1/ATP1A3/ATP2A3/COX5A/SLC8A1	5
KEGG	hsa00030	Pentose phosphate pathway	2/411	30/8135	0.4521	0.9923	0.9505	GLYCTK/ALDOB	2
KEGG	hsa00053	Ascorbate and aldarate metabolism	2/411	30/8135	0.4521	0.9923	0.9505	UGT2B7/UGT2B17	2
KEGG	hsa00630	Glyoxylate and dicarboxylate metabolism	2/411	30/8135	0.4521	0.9923	0.9505	GLDC/GLYCTK	2
KEGG	hsa04664	Fc epsilon RI signaling pathway	4/411	68/8135	0.4522	0.9923	0.9505	PIK3CD/MAP2K4/INPP5D/MAPK9	4
KEGG	hsa00520	Amino sugar and nucleotide sugar metabolism	3/411	49/8135	0.4534	0.9923	0.9505	GNPDA2/TSTA3/NPL	3
KEGG	hsa05205	Proteoglycans in cancer	11/411	205/8135	0.4632	0.9923	0.9505	PIK3CD/ARAF/FZD2/HCLS1/ARHGEF1/FZD7/IGF1R/ROCK2/ELK1/PDCD4/FASLG	11
KEGG	hsa04924	Renin secretion	4/411	69/8135	0.4635	0.9923	0.9505	AQP1/PDE3A/EDN1/PPP3CA	4
KEGG	hsa04931	Insulin resistance	6/411	108/8135	0.4661	0.9923	0.9505	PIK3CD/PPP1R3C/CRTC2/RPS6KA1/PRKCZ/MAPK9	6
KEGG	hsa00410	beta-Alanine metabolism	2/411	31/8135	0.4692	0.9923	0.9505	CNDP2/SMOX	2
KEGG	hsa04710	Circadian rhythm	2/411	31/8135	0.4692	0.9923	0.9505	RORC/PER3	2
KEGG	hsa04976	Bile secretion	5/411	89/8135	0.4701	0.9923	0.9505	AQP1/UGT2B7/UGT2B17/ABCB4/ATP1A3	5
KEGG	hsa04310	Wnt signaling pathway	9/411	167/8135	0.4704	0.9923	0.9505	WIF1/RYK/FZD2/PPP3CA/TCF7L2/FZD7/ROCK2/LEF1/MAPK9	9
KEGG	hsa04622	RIG-I-like receptor signaling pathway	4/411	70/8135	0.4747	0.9923	0.9505	IRF7/TRAF3/TRAF2/MAPK9	4
KEGG	hsa04066	HIF-1 signaling pathway	6/411	109/8135	0.4751	0.9923	0.9505	PIK3CD/VHL/EDN1/IGF1R/ALDOB/LDHAL6A	6
KEGG	hsa05014	Amyotrophic lateral sclerosis	19/411	364/8135	0.4759	0.9923	0.9505	RAB8A/NUP37/DNAH3/PPP3CA/SEH1L/COX7A1/GPX3/PSMC3/KLC2/NUP50/PFN2/PSMB3/ANXA7/COX5A/TRAF2/NDUFS6/TNFRSF1B/GPX2/PINK1	19
KEGG	hsa04926	Relaxin signaling pathway	7/411	129/8135	0.4789	0.9923	0.9505	PIK3CD/EDN1/MAP2K4/GNGT2/PRKCZ/INSL3/MAPK9	7
KEGG	hsa05131	Shigellosis	13/411	247/8135	0.4808	0.9923	0.9505	PIK3CD/U2AF1L4/ARPC5L/RRAGA/HCLS1/ARHGEF2/ROCK2/PFN2/CAPN1/ARPC3/TRAF2/CAPN2/MAPK9	13
KEGG	hsa04514	Cell adhesion molecules	8/411	149/8135	0.4821	0.9923	0.9505	CLDN4/CDH1/CD6/PDCD1/PTPRM/CD2/CD28/ITGAL	8
KEGG	hsa04215	Apoptosis - multiple species	2/411	32/8135	0.486	0.9923	0.9505	BCL2L11/MAPK9	2
KEGG	hsa03450	Non-homologous end-joining	1/411	13/8135	0.4906	0.9923	0.9505	FEN1	1
KEGG	hsa05164	Influenza A	9/411	171/8135	0.4991	0.9923	0.9505	PIK3CD/IRF7/DNAJC3/IFNAR1/TLR3/TRAF3/IL1A/STAT2/FASLG	9
KEGG	hsa05320	Autoimmune thyroid disease	3/411	53/8135	0.5057	0.9923	0.9505	TSHR/CD28/FASLG	3
KEGG	hsa01524	Platinum drug resistance	4/411	73/8135	0.5077	0.9923	0.9505	GSTM3/PIK3CD/TOP2A/FASLG	4
KEGG	hsa05323	Rheumatoid arthritis	5/411	93/8135	0.5092	0.9923	0.9505	IL15/CD28/IL1A/ITGAL/IL23A	5
KEGG	hsa00040	Pentose and glucuronate interconversions	2/411	34/8135	0.5184	0.9923	0.9505	UGT2B7/UGT2B17	2
KEGG	hsa04151	PI3K-Akt signaling pathway	18/411	354/8135	0.5245	0.9923	0.9505	PIK3CD/BCL2L11/FGF17/ITGB6/CCNE1/MYB/IFNAR1/IL2RA/CCNE2/CRTC2/HSP90B1/YWHAQ/TCL1A/IGF1R/FGF23/GNGT2/F2R/FASLG	18
KEGG	hsa01200	Carbon metabolism	6/411	115/8135	0.5278	0.9923	0.9505	ESD/GLDC/IDH2/GLYCTK/GOT1/ALDOB	6
KEGG	hsa01230	Biosynthesis of amino acids	4/411	75/8135	0.5292	0.9923	0.9505	IDH2/CBS/GOT1/ALDOB	4
KEGG	hsa05022	Pathways of neurodegeneration - multiple diseases	24/411	476/8135	0.5358	0.9923	0.9505	RAB8A/DNAH3/ARAF/FZD2/PPP3CA/COX7A1/GPX3/PSMC3/KLC2/FZD7/PSMB3/ATP2A3/CAPN1/COX5A/TRAF2/CAPN2/NDUFS6/IL1A/TNFRSF1B/AGER/GPX2/FASLG/MAPK9/PINK1	24
KEGG	hsa00603	Glycosphingolipid biosynthesis - globo and isoglobo series	1/411	15/8135	0.5408	0.9923	0.9505	ST3GAL2	1
KEGG	hsa00604	Glycosphingolipid biosynthesis - ganglio series	1/411	15/8135	0.5408	0.9923	0.9505	ST3GAL2	1
KEGG	hsa00500	Starch and sucrose metabolism	2/411	36/8135	0.5495	0.9923	0.9505	ENPP1/GANC	2
KEGG	hsa00512	Mucin type O-glycan biosynthesis	2/411	36/8135	0.5495	0.9923	0.9505	ST3GAL2/GALNT11	2
KEGG	hsa04925	Aldosterone synthesis and secretion	5/411	98/8135	0.5563	0.9923	0.9505	CYP11A1/CYP11B2/ATP1A3/HSD3B1/PRKD2	5
KEGG	hsa04722	Neurotrophin signaling pathway	6/411	119/8135	0.5617	0.9923	0.9505	PIK3CD/ARHGDIB/TP73/RPS6KA1/FASLG/MAPK9	6
KEGG	hsa00360	Phenylalanine metabolism	1/411	16/8135	0.5641	0.9923	0.9505	GOT1	1
KEGG	hsa00430	Taurine and hypotaurine metabolism	1/411	16/8135	0.5641	0.9923	0.9505	CDO1	1
KEGG	hsa04960	Aldosterone-regulated sodium reabsorption	2/411	37/8135	0.5645	0.9923	0.9505	PIK3CD/ATP1A3	2
KEGG	hsa05143	African trypanosomiasis	2/411	37/8135	0.5645	0.9923	0.9505	TLR9/FASLG	2
KEGG	hsa04640	Hematopoietic cell lineage	5/411	99/8135	0.5654	0.9923	0.9505	CD5/IL2RA/CD3E/CD2/IL1A	5
KEGG	hsa01521	EGFR tyrosine kinase inhibitor resistance	4/411	79/8135	0.5708	0.9923	0.9505	PIK3CD/BCL2L11/ARAF/IGF1R	4
KEGG	hsa05010	Alzheimer disease	19/411	384/8135	0.5728	0.9923	0.9505	PIK3CD/SLC39A11/ARAF/FZD2/PPP3CA/COX7A1/PSMC3/KLC2/FZD7/PSMB3/ATP2A3/CAPN1/COX5A/TRAF2/CAPN2/NDUFS6/IL1A/AGER/MAPK9	19
KEGG	hsa04140	Autophagy - animal	7/411	141/8135	0.5742	0.9923	0.9505	PIK3CD/RAB8A/RRAGA/IGF1R/MTMR4/GABARAPL1/MAPK9	7
KEGG	hsa05208	Chemical carcinogenesis - reactive oxygen species	11/411	223/8135	0.5774	0.9923	0.9505	GSTM3/PIK3CD/ARAF/MAP2K4/COX7A1/ACP1/SLC26A6/COX5A/NDUFS6/PRKD2/MAPK9	11
KEGG	hsa04630	JAK-STAT signaling pathway	8/411	162/8135	0.5783	0.9923	0.9505	PIK3CD/IFNAR1/IL15/IL2RA/IL27RA/PIM1/STAT2/IL23A	8
KEGG	hsa04330	Notch signaling pathway	3/411	59/8135	0.579	0.9923	0.9505	MFNG/HDAC1/HEYL	3
KEGG	hsa04370	VEGF signaling pathway	3/411	59/8135	0.579	0.9923	0.9505	PIK3CD/SPHK2/PPP3CA	3
KEGG	hsa05330	Allograft rejection	2/411	38/8135	0.5792	0.9923	0.9505	CD28/FASLG	2
KEGG	hsa04936	Alcoholic liver disease	7/411	142/8135	0.5818	0.9923	0.9505	MAP2K4/TCF7L2/TRAF3/LBP/LEF1/FASLG/MAPK9	7
KEGG	hsa04916	Melanogenesis	5/411	101/8135	0.5834	0.9923	0.9505	FZD2/EDN1/TCF7L2/FZD7/LEF1	5
KEGG	hsa05016	Huntington disease	15/411	306/8135	0.5871	0.9923	0.9505	DNAH3/COX7A1/GPX3/PSMC3/KLC2/POLR2D/PSMB3/AP2S1/HDAC1/COX5A/TRAF2/NDUFS6/GPX2/POLR2A/MAPK9	15
KEGG	hsa04621	NOD-like receptor signaling pathway	9/411	184/8135	0.5888	0.9923	0.9505	IRF7/IFNAR1/TRAF3/GABARAPL1/TRAF2/RIPK3/STAT2/CARD9/MAPK9	9
KEGG	hsa04978	Mineral absorption	3/411	60/8135	0.5906	0.9923	0.9505	ATP1A3/SLC26A6/SLC8A1	3
KEGG	hsa00513	Various types of N-glycan biosynthesis	2/411	39/8135	0.5934	0.9923	0.9505	B4GALT3/STT3A	2
KEGG	hsa00511	Other glycan degradation	1/411	18/8135	0.6071	0.9999	0.9578	NEU1	1
KEGG	hsa00670	One carbon pool by folate	1/411	20/8135	0.6459	0.9999	0.9578	TYMS	1
KEGG	hsa00860	Porphyrin metabolism	2/411	43/8135	0.6469	0.9999	0.9578	UGT2B7/UGT2B17	2
KEGG	hsa04720	Long-term potentiation	3/411	67/8135	0.6654	0.9999	0.9578	ARAF/PPP3CA/RPS6KA1	3
KEGG	hsa05410	Hypertrophic cardiomyopathy	4/411	90/8135	0.6737	0.9999	0.9578	ITGB6/EDN1/ATP2A3/SLC8A1	4
KEGG	hsa04270	Vascular smooth muscle contraction	6/411	134/8135	0.6772	0.9999	0.9578	CALCB/ARAF/EDN1/ARHGEF1/ADORA2A/ROCK2	6
KEGG	hsa00220	Arginine biosynthesis	1/411	22/8135	0.6808	0.9999	0.9578	GOT1	1
KEGG	hsa00340	Histidine metabolism	1/411	22/8135	0.6808	0.9999	0.9578	CNDP2	1
KEGG	hsa04920	Adipocytokine signaling pathway	3/411	69/8135	0.6849	0.9999	0.9578	TRAF2/TNFRSF1B/MAPK9	3
KEGG	hsa05204	Chemical carcinogenesis - DNA adducts	3/411	69/8135	0.6849	0.9999	0.9578	GSTM3/UGT2B7/UGT2B17	3
KEGG	hsa05211	Renal cell carcinoma	3/411	69/8135	0.6849	0.9999	0.9578	PIK3CD/VHL/ARAF	3
KEGG	hsa04510	Focal adhesion	9/411	201/8135	0.6934	0.9999	0.9578	PIK3CD/ITGB6/PIP5K1A/IGF1R/ROCK2/ARHGAP5/ELK1/CAPN2/MAPK9	9
KEGG	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	3/411	70/8135	0.6943	0.9999	0.9578	MAP2K4/TJP1/MAPK9	3
KEGG	hsa05230	Central carbon metabolism in cancer	3/411	70/8135	0.6943	0.9999	0.9578	PIK3CD/IDH2/LDHAL6A	3
KEGG	hsa04973	Carbohydrate digestion and absorption	2/411	47/8135	0.6947	0.9999	0.9578	PIK3CD/ATP1A3	2
KEGG	hsa00515	Mannose type O-glycan biosynthesis	1/411	23/8135	0.697	0.9999	0.9578	B4GALT3	1
KEGG	hsa04910	Insulin signaling pathway	6/411	137/8135	0.6978	0.9999	0.9578	PIK3CD/ARAF/PPP1R3C/ELK1/PRKCZ/MAPK9	6
KEGG	hsa05415	Diabetic cardiomyopathy	9/411	203/8135	0.7046	0.9999	0.9578	PIK3CD/PARP1/COX7A1/ATP2A3/PRKCZ/COX5A/NDUFS6/AGER/MAPK9	9
KEGG	hsa04350	TGF-beta signaling pathway	4/411	94/8135	0.7065	0.9999	0.9578	INHBA/BMPR1A/FMOD/RGMB	4
KEGG	hsa04657	IL-17 signaling pathway	4/411	94/8135	0.7065	0.9999	0.9578	TRAF3/HSP90B1/TRAF2/MAPK9	4
KEGG	hsa05206	MicroRNAs in cancer	14/411	310/8135	0.7076	0.9999	0.9578	E2F2/PIK3CD/CDC25A/BCL2L11/CDCA5/KIF23/CCNE1/EZH2/CCNE2/PIM1/DNMT1/HDAC1/PDCD4/E2F1	14
KEGG	hsa00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	1/411	24/8135	0.7124	0.9999	0.9578	HS3ST1	1
KEGG	hsa04977	Vitamin digestion and absorption	1/411	24/8135	0.7124	0.9999	0.9578	SLC19A1	1
KEGG	hsa00982	Drug metabolism - cytochrome P450	3/411	72/8135	0.7125	0.9999	0.9578	GSTM3/UGT2B7/UGT2B17	3
KEGG	hsa00565	Ether lipid metabolism	2/411	49/8135	0.7165	0.9999	0.9578	PAFAH1B3/PAFAH1B1	2
KEGG	hsa00510	N-Glycan biosynthesis	2/411	50/8135	0.7269	0.9999	0.9578	B4GALT3/STT3A	2
KEGG	hsa03015	mRNA surveillance pathway	4/411	97/8135	0.7296	0.9999	0.9578	CPSF3/SMG7/DAZAP1/DDX19A	4
KEGG	hsa04152	AMPK signaling pathway	5/411	120/8135	0.7322	0.9999	0.9578	PIK3CD/RAB8A/CCNA2/CRTC2/IGF1R	5
KEGG	hsa05020	Prion disease	12/411	273/8135	0.7327	0.9999	0.9578	PIK3CD/PPP3CA/COX7A1/PSMC3/KLC2/PSMB3/COX5A/NDUFS6/IL1A/STIP1/MAPK9/HSPA1L	12
KEGG	hsa05017	Spinocerebellar ataxia	6/411	143/8135	0.7363	0.9999	0.9578	PIK3CD/PSMC3/PSMB3/ATP2A3/TRAF2/MAPK9	6
KEGG	hsa05231	Choline metabolism in cancer	4/411	98/8135	0.737	0.9999	0.9578	PIK3CD/DGKE/PIP5K1A/MAPK9	4
KEGG	hsa00790	Folate biosynthesis	1/411	26/8135	0.7408	0.9999	0.9578	GGH	1
KEGG	hsa04950	Maturity onset diabetes of the young	1/411	26/8135	0.7408	0.9999	0.9578	FOXA3	1
KEGG	hsa05133	Pertussis	3/411	76/8135	0.7463	0.9999	0.9578	IL1A/IL23A/MAPK9	3
KEGG	hsa05207	Chemical carcinogenesis - receptor activation	9/411	212/8135	0.7515	0.9999	0.9578	GSTM3/UGT2B7/UGT2B17/PIK3CD/CDC25A/FGF17/RPS6KA1/HSP90B1/E2F1	9
KEGG	hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	1/411	27/8135	0.7539	0.9999	0.9578	B4GALT3	1
KEGG	hsa04611	Platelet activation	5/411	124/8135	0.7581	0.9999	0.9578	PIK3CD/ARHGEF1/ROCK2/PRKCZ/F2R	5
KEGG	hsa04062	Chemokine signaling pathway	8/411	192/8135	0.7616	0.9999	0.9578	PIK3CD/CX3CL1/CCR10/ROCK2/GNGT2/PRKCZ/STAT2/CCL25	8
KEGG	hsa00980	Metabolism of xenobiotics by cytochrome P450	3/411	78/8135	0.762	0.9999	0.9578	GSTM3/UGT2B7/UGT2B17	3
KEGG	hsa00650	Butanoate metabolism	1/411	28/8135	0.7664	0.9999	0.9578	OXCT2	1
KEGG	hsa05202	Transcriptional misregulation in cancer	8/411	193/8135	0.7666	0.9999	0.9578	SS18/CCNA2/WT1/SIX4/IGF1R/MPO/HDAC1/HOXA10	8
KEGG	hsa04974	Protein digestion and absorption	4/411	103/8135	0.7716	0.9999	0.9578	ATP1A3/SLC36A1/SLC8A1/COL14A1	4
KEGG	hsa04744	Phototransduction	1/411	29/8135	0.7782	0.9999	0.9578	PDE6G	1
KEGG	hsa04340	Hedgehog signaling pathway	2/411	56/8135	0.7828	0.9999	0.9578	GAS1/BOC	2
KEGG	hsa04923	Regulation of lipolysis in adipocytes	2/411	56/8135	0.7828	0.9999	0.9578	PIK3CD/TSHR	2
KEGG	hsa00020	Citrate cycle (TCA cycle)	1/411	30/8135	0.7895	0.9999	0.9578	IDH2	1
KEGG	hsa05134	Legionellosis	2/411	57/8135	0.791	0.9999	0.9578	BCL2L13/HSPA1L	2
KEGG	hsa04146	Peroxisome	3/411	82/8135	0.7911	0.9999	0.9578	IDH2/PEX13/PMVK	3
KEGG	hsa05012	Parkinson disease	11/411	266/8135	0.7954	0.9999	0.9578	SLC39A11/COX7A1/PSMC3/KLC2/ADORA2A/PSMB3/COX5A/NDUFS6/DUSP1/MAPK9/PINK1	11
KEGG	hsa00052	Galactose metabolism	1/411	31/8135	0.8002	0.9999	0.9578	GANC	1
KEGG	hsa00640	Propanoate metabolism	1/411	32/8135	0.8103	0.9999	0.9578	LDHAL6A	1
KEGG	hsa04136	Autophagy - other	1/411	32/8135	0.8103	0.9999	0.9578	GABARAPL1	1
KEGG	hsa04730	Long-term depression	2/411	60/8135	0.8142	0.9999	0.9578	ARAF/IGF1R	2
KEGG	hsa05416	Viral myocarditis	2/411	60/8135	0.8142	0.9999	0.9578	CD28/ITGAL	2
KEGG	hsa03010	Ribosome	6/411	158/8135	0.8169	0.9999	0.9578	MRPL28/MRPL12/RPS15/MRPL36/RPL15/RPL10L	6
KEGG	hsa00561	Glycerolipid metabolism	2/411	61/8135	0.8214	0.9999	0.9578	DGKE/GLYCTK	2
KEGG	hsa00590	Arachidonic acid metabolism	2/411	61/8135	0.8214	0.9999	0.9578	GPX3/GPX2	2
KEGG	hsa04512	ECM-receptor interaction	3/411	88/8135	0.8291	0.9999	0.9578	HMMR/ITGB6/CD47	3
KEGG	hsa05168	Herpes simplex virus 1 infection	21/411	495/8135	0.8297	0.9999	0.9578	PIK3CD/IRF7/CALR/ZNF25/IFNAR1/ZNF230/ZNF160/ZNF514/TLR3/TRAF3/ZNF169/ZNF200/ZNF10/ZNF577/TRAF2/STAT2/ZNF667/CARD9/TNFRSF14/TLR9/FASLG	21
KEGG	hsa04211	Longevity regulating pathway	3/411	89/8135	0.8348	0.9999	0.9578	SESN3/PIK3CD/IGF1R	3
KEGG	hsa04727	GABAergic synapse	3/411	89/8135	0.8348	0.9999	0.9578	SLC38A5/GNGT2/GABARAPL1	3
KEGG	hsa03250	Viral life cycle - HIV-1	2/411	63/8135	0.835	0.9999	0.9578	APOBEC3C/SMARCB1	2
KEGG	hsa04623	Cytosolic DNA-sensing pathway	2/411	63/8135	0.835	0.9999	0.9578	IRF7/RIPK3	2
KEGG	hsa05171	Coronavirus disease - COVID-19	9/411	232/8135	0.8365	0.9999	0.9578	PIK3CD/IFNAR1/TLR3/TRAF3/RPS15/RPL15/STAT2/MAPK9/RPL10L	9
KEGG	hsa04929	GnRH secretion	2/411	64/8135	0.8415	0.9999	0.9578	PIK3CD/KISS1R	2
KEGG	hsa05032	Morphine addiction	3/411	91/8135	0.8457	0.9999	0.9578	PDE3A/PDE4C/GNGT2	3
KEGG	hsa00350	Tyrosine metabolism	1/411	36/8135	0.846	0.9999	0.9578	GOT1	1
KEGG	hsa04927	Cortisol synthesis and secretion	2/411	65/8135	0.8477	0.9999	0.9578	CYP11A1/HSD3B1	2
KEGG	hsa00970	Aminoacyl-tRNA biosynthesis	2/411	66/8135	0.8538	0.9999	0.9578	SARS2/NARS2	2
KEGG	hsa00250	Alanine, aspartate and glutamate metabolism	1/411	37/8135	0.8538	0.9999	0.9578	GOT1	1
KEGG	hsa01250	Biosynthesis of nucleotide sugars	1/411	37/8135	0.8538	0.9999	0.9578	TSTA3	1
KEGG	hsa04022	cGMP-PKG signaling pathway	6/411	167/8135	0.8551	0.9999	0.9578	PDE3A/PPP3CA/ROCK2/ATP1A3/ATP2A3/SLC8A1	6
KEGG	hsa04912	GnRH signaling pathway	3/411	93/8135	0.856	0.9999	0.9578	MAP2K4/ELK1/MAPK9	3
KEGG	hsa00010	Glycolysis / Gluconeogenesis	2/411	67/8135	0.8595	0.9999	0.9578	ALDOB/LDHAL6A	2
KEGG	hsa04080	Neuroactive ligand-receptor interaction	14/411	353/8135	0.861	0.9999	0.9578	CALCB/GPR35/GRIK5/NMU/EDN1/GALR2/TSHR/ADORA2A/CHRNA6/P2RX3/PYY/KISS1R/INSL3/F2R	14
KEGG	hsa04020	Calcium signaling pathway	9/411	240/8135	0.8635	0.9999	0.9578	FGF17/SPHK2/PPP3CA/ADORA2A/P2RX3/FGF23/ATP2A3/F2R/SLC8A1	9
KEGG	hsa00830	Retinol metabolism	2/411	68/8135	0.8651	0.9999	0.9578	UGT2B7/UGT2B17	2
KEGG	hsa04919	Thyroid hormone signaling pathway	4/411	121/8135	0.8673	0.9999	0.9578	PIK3CD/ATP1A3/ATP2A3/HDAC1	4
KEGG	hsa05414	Dilated cardiomyopathy	3/411	96/8135	0.8704	0.9999	0.9578	ITGB6/ATP2A3/SLC8A1	3
KEGG	hsa05031	Amphetamine addiction	2/411	69/8135	0.8705	0.9999	0.9578	PPP3CA/HDAC1	2
KEGG	hsa05033	Nicotine addiction	1/411	40/8135	0.8749	0.9999	0.9578	CHRNA6	1
KEGG	hsa04072	Phospholipase D signaling pathway	5/411	148/8135	0.8751	0.9999	0.9578	PIK3CD/DGKE/SPHK2/PIP5K1A/F2R	5
KEGG	hsa04917	Prolactin signaling pathway	2/411	70/8135	0.8757	0.9999	0.9578	PIK3CD/MAPK9	2
KEGG	hsa00380	Tryptophan metabolism	1/411	42/8135	0.8873	0.9999	0.9578	GCDH	1
KEGG	hsa00071	Fatty acid degradation	1/411	43/8135	0.893	0.9999	0.9578	GCDH	1
KEGG	hsa04972	Pancreatic secretion	3/411	102/8135	0.8953	0.9999	0.9578	RAB8A/ATP1A3/ATP2A3	3
KEGG	hsa04962	Vasopressin-regulated water reabsorption	1/411	44/8135	0.8985	0.9999	0.9578	ARHGDIB	1
KEGG	hsa02010	ABC transporters	1/411	45/8135	0.9036	0.9999	0.9578	ABCB4	1
KEGG	hsa03022	Basal transcription factors	1/411	45/8135	0.9036	0.9999	0.9578	TAF5	1
KEGG	hsa04014	Ras signaling pathway	8/411	232/8135	0.9067	0.9999	0.9578	PIK3CD/FGF17/IGF1R/FGF23/GNGT2/ELK1/FASLG/MAPK9	8
KEGG	hsa05140	Leishmaniasis	2/411	77/8135	0.9069	0.9999	0.9578	ELK1/IL1A	2
KEGG	hsa04922	Glucagon signaling pathway	3/411	107/8135	0.9127	0.9999	0.9578	PPP3CA/CRTC2/LDHAL6A	3
KEGG	hsa00620	Pyruvate metabolism	1/411	47/8135	0.9132	0.9999	0.9578	LDHAL6A	1
KEGG	hsa00280	Valine, leucine and isoleucine degradation	1/411	48/8135	0.9176	0.9999	0.9578	OXCT2	1
KEGG	hsa04371	Apelin signaling pathway	4/411	139/8135	0.9264	0.9999	0.9578	CDH1/SPHK2/GNGT2/SLC8A1	4
KEGG	hsa04725	Cholinergic synapse	3/411	113/8135	0.9301	0.9999	0.9578	PIK3CD/CHRNA6/GNGT2	3
KEGG	hsa04724	Glutamatergic synapse	3/411	114/8135	0.9327	0.9999	0.9578	GRIK5/PPP3CA/GNGT2	3
KEGG	hsa04610	Complement and coagulation cascades	2/411	85/8135	0.9336	0.9999	0.9578	CD46/F2R	2
KEGG	hsa04726	Serotonergic synapse	3/411	115/8135	0.9352	0.9999	0.9578	ARAF/GNGT2/DUSP1	3
KEGG	hsa04935	Growth hormone synthesis, secretion and action	3/411	119/8135	0.9443	0.9999	0.9578	PIK3CD/MAP2K4/MAPK9	3
KEGG	hsa04145	Phagosome	4/411	152/8135	0.953	0.9999	0.9578	SEC61A1/CALR/CORO1A/MPO	4
KEGG	hsa04713	Circadian entrainment	2/411	97/8135	0.9605	0.9999	0.9578	PER3/GNGT2	2
KEGG	hsa04750	Inflammatory mediator regulation of TRP channels	2/411	98/8135	0.9622	0.9999	0.9578	PIK3CD/MAPK9	2
KEGG	hsa04142	Lysosome	3/411	132/8135	0.9663	0.9999	0.9578	NEU1/CTSZ/AP1G2	3
KEGG	hsa04728	Dopaminergic synapse	3/411	132/8135	0.9663	0.9999	0.9578	PPP3CA/GNGT2/MAPK9	3
KEGG	hsa04613	Neutrophil extracellular trap formation	5/411	190/8135	0.967	0.9999	0.9578	PIK3CD/MPO/HDAC1/ITGAL/AGER	5
KEGG	hsa00190	Oxidative phosphorylation	3/411	134/8135	0.9689	0.9999	0.9578	COX7A1/COX5A/NDUFS6	3
KEGG	hsa04915	Estrogen signaling pathway	3/411	138/8135	0.9735	0.9999	0.9578	PIK3CD/HSP90B1/HSPA1L	3
KEGG	hsa04714	Thermogenesis	6/411	232/8135	0.9796	0.9999	0.9578	SMARCD1/COX7A1/RPS6KA1/SMARCB1/COX5A/NDUFS6	6
KEGG	hsa05145	Toxoplasmosis	2/411	112/8135	0.9797	0.9999	0.9578	MAPK9/HSPA1L	2
KEGG	hsa04971	Gastric acid secretion	1/411	76/8135	0.9809	0.9999	0.9578	ATP1A3	1
KEGG	hsa04723	Retrograde endocannabinoid signaling	3/411	148/8135	0.9823	0.9999	0.9578	GNGT2/NDUFS6/MAPK9	3
KEGG	hsa04721	Synaptic vesicle cycle	1/411	78/8135	0.9828	0.9999	0.9578	AP2S1	1
KEGG	hsa04261	Adrenergic signaling in cardiomyocytes	3/411	150/8135	0.9837	0.9999	0.9578	ATP1A3/ATP2A3/SLC8A1	3
KEGG	hsa04921	Oxytocin signaling pathway	3/411	154/8135	0.9861	0.9999	0.9578	PPP3CA/ROCK2/ELK1	3
KEGG	hsa05034	Alcoholism	4/411	187/8135	0.9871	0.9999	0.9578	ARAF/ADORA2A/GNGT2/HDAC1	4
KEGG	hsa04742	Taste transduction	1/411	86/8135	0.9887	0.9999	0.9578	P2RX3	1
KEGG	hsa04911	Insulin secretion	1/411	86/8135	0.9887	0.9999	0.9578	ATP1A3	1
KEGG	hsa04540	Gap junction	1/411	88/8135	0.9898	0.9999	0.9578	TJP1	1
KEGG	hsa04970	Salivary secretion	1/411	93/8135	0.9922	0.9999	0.9578	ATP1A3	1
KEGG	hsa05150	Staphylococcus aureus infection	1/411	96/8135	0.9933	0.9999	0.9578	ITGAL	1
KEGG	hsa00564	Glycerophospholipid metabolism	1/411	98/8135	0.994	0.9999	0.9578	DGKE	1
KEGG	hsa05146	Amoebiasis	1/411	102/8135	0.9951	0.9999	0.9578	PIK3CD	1
KEGG	hsa05322	Systemic lupus erythematosus	1/411	136/8135	0.9992	0.9999	0.9578	CD28	1
KEGG	hsa04740	Olfactory transduction	8/411	440/8135	0.9999	0.9999	0.9578	OR1L1/OR9Q1/OR10H4/OR5M3/OR11H4/CNGA4/OR5M1/SLC8A1	8