ONTOLOGY	ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	qvalue	geneID	Count
BP	GO:0034341	response to interferon-gamma	70/2306	199/18670	5.75e-17	3.554e-13	2.734e-13	CCL20/ICAM1/CCL5/VCAM1/MT2A/CLDN1/IRF9/CCL2/CCL8/IRF1/OAS1/PARP14/CCL7/IFNGR1/OAS3/IFITM1/KYNU/IFNGR2/GBP2/DAPK1/STAT1/IRF7/MID1/GBP5/HLA-E/CCL3L3/SOCS1/SOCS3/ACTR3/CD44/TRIM25/HLA-F/CD58/OAS2/CAMK2D/GBP3/NUB1/CCL3/GBP1/GBP4/GCH1/HLA-A/OASL/EDN1/CYP27B1/SIRPA/CCL1/PDE12/FLNB/PARP9/WNT5A/TRIM21/GSN/CAMK2G/ASS1/SP100/UBD/STXBP1/TLR3/SYNCRIP/PRKCD/HLA-G/ZYX/HLA-DQB1/PPARG/ACTR2/TRIM38/ACTG1/HLA-B/HLA-H	70
BP	GO:0071346	cellular response to interferon-gamma	64/2306	180/18670	6.826e-16	2.109e-12	1.623e-12	CCL20/ICAM1/CCL5/VCAM1/MT2A/CLDN1/IRF9/CCL2/CCL8/IRF1/OAS1/PARP14/CCL7/IFNGR1/OAS3/IFNGR2/GBP2/DAPK1/STAT1/IRF7/MID1/GBP5/HLA-E/CCL3L3/SOCS1/SOCS3/ACTR3/CD44/TRIM25/HLA-F/CD58/OAS2/CAMK2D/GBP3/CCL3/GBP1/GBP4/HLA-A/OASL/EDN1/SIRPA/CCL1/PDE12/FLNB/PARP9/WNT5A/TRIM21/GSN/CAMK2G/ASS1/SP100/STXBP1/TLR3/SYNCRIP/PRKCD/HLA-G/ZYX/HLA-DQB1/PPARG/ACTR2/TRIM38/ACTG1/HLA-B/HLA-H	64
BP	GO:0009615	response to virus	89/2306	326/18670	1.682e-13	3.464e-10	2.665e-10	BIRC3/ZC3H12A/TNFAIP3/CCL5/IL6/IL1B/MX1/CXCL10/IL33/IRF9/ISG20/CCL8/CDK6/HSPB1/IRF1/OAS1/IFIH1/IFNAR2/IFI44L/IFNGR1/IFNAR1/MX2/BIRC2/ISG15/OAS3/XPR1/IFITM1/RSAD2/IFNGR2/PLSCR1/STAT1/DDX60/IRF7/TRAF3/IL12A/IFIT1/APOBEC3G/TSPAN6/TRIM25/CD40/IRAK3/PIM2/OAS2/DDX58/TRAF3IP2/GBP3/ADAR/FADD/GBP1/IFIT3/ITCH/OASL/IL15/EIF2AK4/DHX58/IFI44/APOBEC3H/CXCL9/PMAIP1/DMBT1/STAT2/DNAJC3/PDE12/RTP4/BATF3/PARP9/BCL3/POLR3D/ATG7/BCL2L1/FAM111A/ARF1/IFIT2/MICB/PRKRA/TNF/HERC5/IVNS1ABP/TLR3/TRIM6/GATA3/ADARB1/APOBEC3F/LGALS8/ABCF3/POLR3K/BTBD17/TICAM1/TRIM38	89
BP	GO:0060337	type I interferon signaling pathway	39/2306	95/18670	1.734e-12	2.143e-09	1.649e-09	MX1/IRF9/IFI35/ISG20/IRF1/OAS1/IFNAR2/IFNAR1/MX2/ISG15/PSMB8/OAS3/IFITM1/RSAD2/GBP2/XAF1/STAT1/IRF7/HLA-E/IFIT1/HLA-F/OAS2/ADAR/FADD/IFIT3/HLA-A/OASL/STAT2/WNT5A/IFIT2/TYK2/SP100/TRIM6/HLA-G/USP18/PTPN11/ZBP1/HLA-B/HLA-H	39
BP	GO:0071357	cellular response to type I interferon	39/2306	95/18670	1.734e-12	2.143e-09	1.649e-09	MX1/IRF9/IFI35/ISG20/IRF1/OAS1/IFNAR2/IFNAR1/MX2/ISG15/PSMB8/OAS3/IFITM1/RSAD2/GBP2/XAF1/STAT1/IRF7/HLA-E/IFIT1/HLA-F/OAS2/ADAR/FADD/IFIT3/HLA-A/OASL/STAT2/WNT5A/IFIT2/TYK2/SP100/TRIM6/HLA-G/USP18/PTPN11/ZBP1/HLA-B/HLA-H	39
BP	GO:0034340	response to type I interferon	39/2306	99/18670	8.089e-12	8.332e-09	6.41e-09	MX1/IRF9/IFI35/ISG20/IRF1/OAS1/IFNAR2/IFNAR1/MX2/ISG15/PSMB8/OAS3/IFITM1/RSAD2/GBP2/XAF1/STAT1/IRF7/HLA-E/IFIT1/HLA-F/OAS2/ADAR/FADD/IFIT3/HLA-A/OASL/STAT2/WNT5A/IFIT2/TYK2/SP100/TRIM6/HLA-G/USP18/PTPN11/ZBP1/HLA-B/HLA-H	39
BP	GO:0032496	response to lipopolysaccharide	85/2306	330/18670	1.73e-11	1.527e-08	1.175e-08	CXCL1/CXCL2/CXCL6/NFKBIA/ZC3H12A/ICAM1/TNFAIP3/IRAK2/BDKRB1/CCL5/PTGS2/IL6/CXCL5/VCAM1/CSF2/IL1B/CLDN1/RIPK2/PTGES/CXCL10/NFKB1/CCL2/NFKB2/TRIB1/ABCA1/PPARGC1A/CEBPB/IFNAR1/PRKCA/PDCD1LG2/TNFRSF1B/TNIP3/PF4V1/IDO1/NFKBIB/IL12A/PTGFR/CXCL3/CMPK2/IRAK3/PDE4D/CXCL11/CCL3/GCH1/ZFP36/EDN1/PTGER2/AKAP12/CYP27B1/CXCL9/HNRNPA0/SIRPA/F2R/ADH5/CYP1A2/LDOC1/GJB2/AXL/MEF2C/JUNB/WNT5A/ABCC2/AKAP8/LOXL1/TIMP4/HAVCR2/TNF/ASS1/SPARC/ATP2A2/IL12RB2/CNR2/TRIM6/CPS1/CHMP5/SERPINE1/ABL1/BCL10/PDE4B/DUSP10/FGF10/TICAM1/MGST2/P2RX7/CAPN2	85
BP	GO:0051607	defense response to virus	67/2306	238/18670	3.835e-11	2.962e-08	2.279e-08	BIRC3/ZC3H12A/TNFAIP3/IL6/IL1B/MX1/CXCL10/IL33/IRF9/ISG20/IRF1/OAS1/IFIH1/IFNAR2/IFI44L/MX2/BIRC2/ISG15/OAS3/IFITM1/RSAD2/PLSCR1/STAT1/DDX60/IRF7/TRAF3/IFIT1/APOBEC3G/TSPAN6/TRIM25/CD40/OAS2/DDX58/TRAF3IP2/GBP3/ADAR/FADD/GBP1/IFIT3/ITCH/OASL/IL15/EIF2AK4/DHX58/APOBEC3H/CXCL9/PMAIP1/DMBT1/STAT2/DNAJC3/PDE12/RTP4/PARP9/POLR3D/ATG7/FAM111A/IFIT2/MICB/HERC5/TLR3/TRIM6/ADARB1/APOBEC3F/ABCF3/POLR3K/TICAM1/TRIM38	67
BP	GO:0060333	interferon-gamma-mediated signaling pathway	36/2306	91/18670	4.422e-11	3.036e-08	2.336e-08	ICAM1/VCAM1/MT2A/IRF9/IRF1/OAS1/PARP14/IFNGR1/OAS3/IFNGR2/GBP2/STAT1/IRF7/MID1/HLA-E/SOCS1/SOCS3/CD44/TRIM25/HLA-F/OAS2/CAMK2D/GBP1/HLA-A/OASL/PARP9/TRIM21/CAMK2G/SP100/PRKCD/HLA-G/HLA-DQB1/PPARG/TRIM38/HLA-B/HLA-H	36
BP	GO:0002237	response to molecule of bacterial origin	85/2306	343/18670	1.463e-10	9.04e-08	6.955e-08	CXCL1/CXCL2/CXCL6/NFKBIA/ZC3H12A/ICAM1/TNFAIP3/IRAK2/BDKRB1/CCL5/PTGS2/IL6/CXCL5/VCAM1/CSF2/IL1B/CLDN1/RIPK2/PTGES/CXCL10/NFKB1/CCL2/NFKB2/TRIB1/ABCA1/PPARGC1A/CEBPB/IFNAR1/PRKCA/PDCD1LG2/TNFRSF1B/TNIP3/PF4V1/IDO1/NFKBIB/IL12A/PTGFR/CXCL3/CMPK2/IRAK3/PDE4D/CXCL11/CCL3/GCH1/ZFP36/EDN1/PTGER2/AKAP12/CYP27B1/CXCL9/HNRNPA0/SIRPA/F2R/ADH5/CYP1A2/LDOC1/GJB2/AXL/MEF2C/JUNB/WNT5A/ABCC2/AKAP8/LOXL1/TIMP4/HAVCR2/TNF/ASS1/SPARC/ATP2A2/IL12RB2/CNR2/TRIM6/CPS1/CHMP5/SERPINE1/ABL1/BCL10/PDE4B/DUSP10/FGF10/TICAM1/MGST2/P2RX7/CAPN2	85
BP	GO:0034612	response to tumor necrosis factor	79/2306	312/18670	2.174e-10	1.221e-07	9.397e-08	NFKBIA/CCL20/BIRC3/ZC3H12A/ICAM1/TNFAIP3/CCL5/PTGS2/CD70/VCAM1/PSME2/PID1/CLDN1/NFKB1/CCL2/PSMA6/CCL8/PSMB10/PPARGC1A/CCL7/TNFSF9/BIRC2/PSMB8/TNFRSF14/PSMB7/TNFRSF9/PSME1/GBP2/TNFRSF1B/STAT1/TNFSF13B/KLF2/TRAF3/PSMB9/CCL3L3/COL1A1/CD58/CD40/GBP3/NUB1/PSMA3/CCL3/GBP1/CYBA/GCH1/THBS1/ZFP36/CYLD/EDN1/AKAP12/ZFP36L2/CCL1/HAS2/PSMA1/CLIP3/PSMB2/SIRT1/TRAF2/ABCC2/NKX3-1/PSMB3/TNF/ASS1/ACTN4/UBD/CEBPA/GATA3/PSMA8/TAX1BP1/RBCK1/GAS6/PYDC2/PSME4/TNFRSF11B/PSMB5/PIAS3/ZNF675/PELI3/PSMF1	79
BP	GO:2000027	regulation of animal organ morphogenesis	68/2306	253/18670	2.542e-10	1.231e-07	9.471e-08	BMP2/TNFAIP3/PSME2/LIF/PSMA6/PSMB10/CSF1/AHI1/CITED2/DAB2/BASP1/PSMB8/PSMB7/SIX1/PSME1/ANKRD6/STAT1/VEGFA/CFLAR/BMP4/PSMB9/FZD1/GPC4/RXRA/BMPR2/LIMS2/PSMA3/HOXA11/PIM1/SULF2/EDN1/ROR1/FZD2/CLTC/TGFB2/SPRY1/SNAI2/CARM1/PSMA1/SIX4/ROBO1/PSMB2/VDR/WNT5A/SULF1/PSMB3/PTK7/TNF/TACSTD2/FZD4/RSPO2/GATA3/PSMA8/HOXB7/LGR4/ABL1/ENG/FGF10/PSME4/CDC42/TNFRSF11B/PSMB5/DVL1/DVL2/FZD7/PLEKHA4/PSMF1/NFIB	68
BP	GO:0071356	cellular response to tumor necrosis factor	75/2306	291/18670	2.589e-10	1.231e-07	9.471e-08	NFKBIA/CCL20/BIRC3/ZC3H12A/ICAM1/TNFAIP3/CCL5/CD70/VCAM1/PSME2/PID1/CLDN1/NFKB1/CCL2/PSMA6/CCL8/PSMB10/PPARGC1A/CCL7/TNFSF9/BIRC2/PSMB8/TNFRSF14/PSMB7/TNFRSF9/PSME1/GBP2/TNFRSF1B/STAT1/TNFSF13B/KLF2/TRAF3/PSMB9/CCL3L3/COL1A1/CD58/CD40/GBP3/PSMA3/CCL3/GBP1/CYBA/THBS1/ZFP36/CYLD/EDN1/AKAP12/ZFP36L2/CCL1/HAS2/PSMA1/CLIP3/PSMB2/SIRT1/TRAF2/ABCC2/NKX3-1/PSMB3/TNF/ASS1/ACTN4/CEBPA/GATA3/PSMA8/TAX1BP1/RBCK1/GAS6/PYDC2/PSME4/TNFRSF11B/PSMB5/PIAS3/ZNF675/PELI3/PSMF1	75
BP	GO:0071347	cellular response to interleukin-1	53/2306	179/18670	5.708e-10	2.52e-07	1.939e-07	NFKBIA/CCL20/ZC3H12A/ICAM1/IRAK2/CCL5/IL6/MAP3K8/PSME2/IL1B/RIPK2/NFKB1/CCL2/PSMA6/CCL8/PSMB10/IL1A/CCL7/SQSTM1/CEBPB/PSMB8/PSMB7/PSME1/GBP2/IRAK4/KLF2/PSMB9/CCL3L3/IRAK3/GBP3/PSMA3/CCL3/GBP1/EDN1/MAPK13/AKAP12/SIRPA/CCL1/RPS6KA4/HAS2/PSMA1/PSMB2/ABCC2/NKX3-1/PSMB3/PSMA8/UBB/PSME4/PSMB5/PELI2/ZNF675/PELI3/PSMF1	53
BP	GO:0070555	response to interleukin-1	57/2306	207/18670	2.668e-09	1.099e-06	8.457e-07	NFKBIA/CCL20/ZC3H12A/ICAM1/IRAK2/CCL5/IL6/MAP3K8/PSME2/IL1B/RIPK2/NFKB1/CCL2/PSMA6/CCL8/PSMB10/IL1A/CCL7/SQSTM1/CEBPB/PSMB8/PRKCA/PSMB7/PSME1/GBP2/IRAK4/KLF2/PSMB9/CCL3L3/IRAK3/ETS1/GBP3/PSMA3/CCL3/GBP1/CYBA/EDN1/MAPK13/AKAP12/HNMT/SIRPA/CCL1/RPS6KA4/HAS2/PSMA1/PSMB2/ABCC2/NKX3-1/PSMB3/PSMA8/UBB/PSME4/PSMB5/PELI2/ZNF675/PELI3/PSMF1	57
BP	GO:0045069	regulation of viral genome replication	34/2306	95/18670	3.407e-09	1.316e-06	1.013e-06	ZC3H12A/CCL5/TNIP1/MX1/ISG20/CCL8/OAS1/ISG15/FBXL2/OAS3/IFITM1/RSAD2/PLSCR1/IFIT1/APOBEC3G/ADAR/OASL/EIF2AK4/APOBEC3H/PPIA/PDE12/PABPC1/FAM111A/RAD23A/DDX5/TNF/STAU1/TRIM6/ADARB1/APOBEC3F/NUCKS1/BTBD17/PKN2/TRIM38	34
BP	GO:0019079	viral genome replication	39/2306	122/18670	1.001e-08	3.639e-06	2.8e-06	ZC3H12A/CCL5/TNIP1/MX1/CCL2/ISG20/CCL8/OAS1/ISG15/FBXL2/OAS3/IFITM1/RSAD2/NFIA/PLSCR1/IFIT1/APOBEC3G/ADAR/OASL/EIF2AK4/APOBEC3H/PPIA/PDE12/PABPC1/FAM111A/RAD23A/DDX5/TNF/STAU1/TRIM6/ADARB1/APOBEC3F/ROCK2/NUCKS1/GAS6/BTBD17/PKN2/CDC42/TRIM38	39
BP	GO:1905330	regulation of morphogenesis of an epithelium	50/2306	180/18670	1.815e-08	6.231e-06	4.794e-06	PSME2/LIF/CXCL10/PSMA6/PSMB10/AHI1/DAB2/PSMB8/PSMB7/SIX1/PSME1/ANKRD6/STAT1/VEGFA/BMP4/PSMB9/FZD1/GPC4/RXRA/PSMA3/ROR1/FZD2/CLTC/SNAI2/PSMA1/SIX4/PSMB2/PHLDB2/WNT5A/SULF1/PSMB3/PTK7/TNF/TACSTD2/FZD4/GATA3/PSMA8/HOXB7/LGR4/ABL1/FGF10/PSME4/CDC42/PSMB5/DVL1/DVL2/FZD7/PLEKHA4/SIRT6/PSMF1	50
BP	GO:0030198	extracellular matrix organization	82/2306	368/18670	5.738e-08	1.866e-05	1.436e-05	ICAM1/IL6/MMP1/VCAM1/ITGA1/NFKB2/MMP3/FSCN1/RECK/FGF2/PDPN/TNFRSF1B/CFLAR/JAM3/CTSS/LAMB1/COL1A1/JAM2/CD44/ETS1/LOXL4/ITGB5/VCAN/VWF/HSPG2/ITGA4/THBS1/SULF2/MYO1E/COL5A2/ERCC2/CCDC80/TGFB2/ITGB8/PHLDB1/ITGA2/CSGALNACT1/PLOD2/HAS2/MMP9/FLOT1/FLRT2/BCL3/MMP17/NID2/MMP11/PHLDB2/CRISPLD2/ITGA11/SULF1/COL6A3/MMP27/HSD17B12/TNC/LOXL1/FBN1/TNF/SH3PXD2B/SPARC/HAS1/SERPINH1/ELF3/HAS3/PTX3/COL16A1/COL4A1/SERPINE1/ABL1/COL24A1/ITGAE/COL1A2/GAS6/MMP24/ENG/TNFRSF11B/FERMT1/ITGA6/ICAM5/SERPINF2/COL5A1/ADAM8/CAPN2	82
BP	GO:0070482	response to oxygen levels	86/2306	394/18670	7.33e-08	2.265e-05	1.743e-05	BMP2/ICAM1/NAMPT/PTGS2/VCAM1/PSME2/SLC11A2/PSMA6/PSMB10/PPARGC1A/ARNT2/CITED2/BIRC2/DDAH1/PSMB8/PSMB7/PSME1/EPAS1/FOXO1/SLC2A1/VEGFA/EEF2K/AGTRAP/HK2/CFLAR/PAK1/PDGFRB/TBL2/PSMB9/MYB/COL1A1/PLAU/ETS1/FAS/PSMA3/LMNA/CYBA/THBS1/WTIP/FMN2/OXTR/ADA/EDN1/EGLN1/CRYAB/PMAIP1/HIPK2/ERCC2/TGFB2/ITGA2/LPAR1/GATA6/PLOD2/CYGB/PSMA1/ASCL2/POLB/ITPR2/PSMB2/SIRT1/ADORA1/ATG7/NKX3-1/PSMB3/ACAA2/ABAT/P2RX3/HMOX2/PGF/HYOU1/ACTN4/PSMA8/PDK3/ROCK2/MIR214/UBB/PPARG/CDKN1A/NPPA/PSME4/FAM162A/PSMB5/CLCA1/ADAM8/CAPN2/PSMF1	86
BP	GO:0043062	extracellular structure organization	90/2306	422/18670	1.127e-07	3.316e-05	2.551e-05	ICAM1/IL6/MMP1/VCAM1/ITGA1/NFKB2/MMP3/ABCA1/FSCN1/RECK/FGF2/PDPN/TNFRSF1B/CFLAR/JAM3/CTSS/LAMB1/COL1A1/JAM2/CD44/ETS1/LOXL4/ITGB5/VCAN/VWF/HSPG2/ITGA4/THBS1/SULF2/MYO1E/COL5A2/SDCBP/LIPG/ERCC2/CCDC80/TGFB2/ITGB8/PHLDB1/ITGA2/ABCA5/CSGALNACT1/PLOD2/HAS2/SOAT1/MMP9/FLOT1/FLRT2/BCL3/MMP17/NID2/MMP11/PHLDB2/CRISPLD2/ITGA11/SULF1/COL6A3/MMP27/ARF1/HSD17B12/TNC/LOXL1/FBN1/TNF/SH3PXD2B/SPARC/HAS1/SERPINH1/ELF3/HAS3/PTX3/COL16A1/COL4A1/SDC4/SERPINE1/ABL1/COL24A1/ITGAE/COL1A2/GAS6/MMP24/ENG/TNFRSF11B/FERMT1/ITGA6/ICAM5/SERPINF2/COL5A1/ADAM8/PDCD6IP/CAPN2	90
BP	GO:0071222	cellular response to lipopolysaccharide	52/2306	205/18670	2.397e-07	6.734e-05	5.181e-05	CXCL1/CXCL2/CXCL6/NFKBIA/ZC3H12A/ICAM1/TNFAIP3/IRAK2/CCL5/IL6/CXCL5/CSF2/IL1B/RIPK2/CXCL10/NFKB1/CCL2/TRIB1/ABCA1/PPARGC1A/CEBPB/PRKCA/PDCD1LG2/TNFRSF1B/TNIP3/PF4V1/NFKBIB/IL12A/CXCL3/CMPK2/PDE4D/CXCL11/CCL3/ZFP36/CXCL9/SIRPA/LDOC1/AXL/MEF2C/WNT5A/ABCC2/AKAP8/HAVCR2/TNF/ASS1/CHMP5/SERPINE1/ABL1/BCL10/PDE4B/TICAM1/CAPN2	52
BP	GO:0033002	muscle cell proliferation	58/2306	239/18670	2.549e-07	6.85e-05	5.27e-05	SOD2/AKR1B1/TNFAIP3/NAMPT/CCL5/PTGS2/IL6/ID2/TRIB1/ERN1/PPARGC1A/NPR3/FGF2/MEIS1/JARID2/SIX1/STAT1/EREG/IRAK4/CFLAR/BMP4/PAK1/PDGFRB/SIX5/IL12A/MYB/RXRA/PDE1A/KLF4/CYBA/THBS1/IL15/PIM1/EDN1/TCF7L2/HBEGF/PDGFD/TGFB2/ITGA2/GATA6/YAP1/MMP9/MEF2C/AKIRIN1/MIR19B2/HES5/FOXJ2/MIR137/TNF/MIR1-2/MIR214/PPARG/CDKN1A/MNAT1/MIR199A2/IGF1/STAT3/SERPINF2	58
BP	GO:0048608	reproductive structure development	90/2306	431/18670	3.038e-07	7.824e-05	6.02e-05	ICAM1/PTGS2/CSF2/LIF/PLCD3/NDP/CITED2/KIT/CEBPB/BASP1/BIRC2/ARID5B/PLCD1/EPAS1/VEGFA/EREG/BMP4/RAB13/PDGFRB/AFP/IRX5/SOCS3/DNAJC19/BCL2L2/RDH10/RXRA/SLIT2/NR2F2/BMPR2/PKD2/CCND1/IDH1/HOXA11/ADA/LHX8/STK4/HOXA10/SRD5A1/CYP27B1/PHLDA2/INHBB/TGFB2/ITGB8/GATA6/NUDT1/LDOC1/GJB2/RHOBTB3/ASB1/ASCL2/SIX4/AXL/VDR/SIRT1/JUNB/WNT5A/NKX3-1/SULF1/BCL2L1/TP63/CDKN1C/TNC/MAMLD1/RBM15/FZD4/EIF2B5/HOXA9/EIF2B4/BIRC6/DLX3/TLR3/CEBPA/PTX3/KRT19/GATA3/ZNF830/EIF2S2/ARID1A/LGR4/PRDM1/UBB/PPARG/PTPN11/FGF10/OSR1/BPTF/CYP19A1/CRKL/ARID4A/TBX3	90
BP	GO:0061458	reproductive system development	90/2306	434/18670	4.183e-07	0.0001033	7.951e-05	ICAM1/PTGS2/CSF2/LIF/PLCD3/NDP/CITED2/KIT/CEBPB/BASP1/BIRC2/ARID5B/PLCD1/EPAS1/VEGFA/EREG/BMP4/RAB13/PDGFRB/AFP/IRX5/SOCS3/DNAJC19/BCL2L2/RDH10/RXRA/SLIT2/NR2F2/BMPR2/PKD2/CCND1/IDH1/HOXA11/ADA/LHX8/STK4/HOXA10/SRD5A1/CYP27B1/PHLDA2/INHBB/TGFB2/ITGB8/GATA6/NUDT1/LDOC1/GJB2/RHOBTB3/ASB1/ASCL2/SIX4/AXL/VDR/SIRT1/JUNB/WNT5A/NKX3-1/SULF1/BCL2L1/TP63/CDKN1C/TNC/MAMLD1/RBM15/FZD4/EIF2B5/HOXA9/EIF2B4/BIRC6/DLX3/TLR3/CEBPA/PTX3/KRT19/GATA3/ZNF830/EIF2S2/ARID1A/LGR4/PRDM1/UBB/PPARG/PTPN11/FGF10/OSR1/BPTF/CYP19A1/CRKL/ARID4A/TBX3	90
BP	GO:1903900	regulation of viral life cycle	41/2306	149/18670	4.444e-07	0.0001033	7.951e-05	ZC3H12A/CCL5/TNIP1/MX1/ISG20/CCL8/OAS1/ISG15/FBXL2/OAS3/IFITM1/RSAD2/PLSCR1/IFIT1/APOBEC3G/TRIM25/CHMP4B/ADAR/OASL/EIF2AK4/APOBEC3H/PPIA/PDE12/PABPC1/TRIM21/FAM111A/RAD23A/GSN/DDX5/TNF/STAU1/TRIM6/PTX3/ADARB1/APOBEC3F/NUCKS1/KPNA2/BTBD17/PKN2/TRIM38/SNX3	41
BP	GO:0031331	positive regulation of cellular catabolic process	78/2306	361/18670	4.515e-07	0.0001033	7.951e-05	ZC3H12A/TNFAIP3/IL6/IL1B/RIPK2/IL33/TRIB1/TRIB2/BAG2/DAB2/TNFRSF1B/FOXO1/DAPK1/SESN1/TP53INP2/HK2/ROCK1/PLK2/NKD2/ANKIB1/PLEKHF1/MOV10/PIM2/FTO/HERPUD1/IRS1/NUB1/DDA1/ITCH/RNF14/ZFP36/TRIB3/EIF2AK4/RDX/RAB3GAP1/ZFP36L2/SH3BP4/ARIH2/CPT1A/TP53INP1/SESN3/CSNK1E/ABCD1/SH3D19/ARIH1/SIRT1/OPTN/PABPC1/VPS35/TRIM21/RNF144B/TPCN1/RGN/CAMKK2/BTG2/SESN2/PAFAH1B2/RAD23A/TNF/CNOT8/ABHD5/CEBPA/DET1/PRKCD/MAGEF1/ROCK2/PIP4K2A/TICAM1/SH3RF2/FBXL5/IGF1/DVL1/P2RX7/ADAM8/ZFAND2A/OSBPL7/ST20/ADRA2A	78
BP	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	26/2306	75/18670	4.79e-07	0.0001057	8.133e-05	PSME2/TAP1/TAP2/PSMA6/PSMB10/PSMB8/PSMB7/PSME1/HLA-E/PSMB9/HLA-F/ITGB5/PSMA3/CYBA/HLA-A/PSMA1/PSMB2/PSMB3/PSMA8/HLA-G/TAPBP/PSME4/PSMB5/HLA-B/HLA-H/PSMF1	26
BP	GO:0043901	negative regulation of multi-organism process	45/2306	171/18670	5.011e-07	0.0001057	8.133e-05	ZC3H12A/TNFAIP3/CCL5/TNIP1/MX1/TRIB1/ISG20/CCL8/OAS1/ISG15/OAS3/IFITM1/RSAD2/PLSCR1/STAT1/IFIT1/APOBEC3G/TSPAN6/TRIM25/CCL3/ITCH/ZFP36/OASL/ADA/EIF2AK4/DHX58/APOBEC3H/TRIM21/FAM111A/MICB/GSN/HAVCR2/TNF/ZP2/TRIM6/PTX3/NPR2/APOBEC3F/ZNF639/ARHGDIB/BTBD17/TRIM38/IGF1/MAPKBP1/SNX3	45
BP	GO:0010499	proteasomal ubiquitin-independent protein catabolic process	13/2306	23/18670	5.166e-07	0.0001057	8.133e-05	PSMA6/PSMB10/PSMB8/PSMB7/PSMB9/PSMA3/ENC1/PSMA1/PSMB2/PSMB3/PSMA8/PSME4/PSMB5	13
BP	GO:0048525	negative regulation of viral process	31/2306	99/18670	5.303e-07	0.0001057	8.133e-05	ZC3H12A/CCL5/TNIP1/MX1/ISG20/CCL8/OAS1/ISG15/OAS3/IFITM1/RSAD2/PLSCR1/STAT1/IFIT1/APOBEC3G/TRIM25/CCL3/ZFP36/OASL/EIF2AK4/APOBEC3H/TRIM21/FAM111A/GSN/TNF/TRIM6/PTX3/APOBEC3F/ZNF639/BTBD17/SNX3	31
BP	GO:0071496	cellular response to external stimulus	74/2306	339/18670	5.85e-07	0.000113	8.693e-05	ZC3H12A/ICAM1/NAMPT/PTGS2/VCAM1/IL1B/NFKB1/IRF1/XPR1/FOXO1/SESN1/GABARAPL1/SLC2A1/SLC38A2/CNN2/TBL2/COL1A1/CD40/FYN/P2RY11/BMPR2/FAS/SSH1/FADD/WIPI1/ITGA4/CYBA/IL15/PIM1/MAP3K1/EIF2AK4/GSDMD/SRD5A1/CYP27B1/INHBB/FNIP1/PMAIP1/PPP1R9B/ITGA2/NUDT1/SNAI2/SESN3/DNAJC15/AXL/VDR/SIRT1/ATG7/KCNB1/SESN2/TNC/P2RX3/MAP3K2/BGLAP/PPM1D/TNFRSF10B/MIR125B1/ASNS/TLR3/GLRX2/KPTN/WDR45/BCL10/PDXP/GAS6/MAX/PPARG/CDKN1A/PTPN11/ENG/NPPA/SIK1/ITGA6/P2RX7/MYBBP1A	74
BP	GO:0000209	protein polyubiquitination	69/2306	310/18670	6.6e-07	0.0001233	9.487e-05	TNFAIP3/HERC6/PSME2/PSMA6/PSMB10/BIRC2/PSMB8/PSMB7/LMO7/PSME1/KLHL3/RNF20/PSMB9/UBE4A/ANKIB1/NFE2L1/CDC16/PSMA3/ITCH/RNF14/ZFP91/RNF114/UBR5/UBE2Q2/ARIH2/HECTD1/DDB2/HECW2/PSMA1/PPIL2/ARIH1/SPSB1/PSMB2/RNF5/TRAF2/ANAPC13/TRIM21/RNF144B/UBE2E1/PSMB3/TRIM2/UBE2T/RNF4/FBXW4/FBXL22/TOPORS/HERC5/KLHL20/TRIM6/PSMA8/FBXO17/RBCK1/UBB/PSME4/FBXL5/PSMB5/TRIM38/CDC23/UBE4B/MYLIP/RNF126/PELI2/NEDD4/BFAR/MAGEL2/UBE2S/PELI3/PSMF1/CBFB	69
BP	GO:0070498	interleukin-1-mediated signaling pathway	31/2306	100/18670	6.784e-07	0.0001233	9.487e-05	NFKBIA/IRAK2/IL6/MAP3K8/PSME2/IL1B/RIPK2/NFKB1/PSMA6/PSMB10/IL1A/SQSTM1/PSMB8/PSMB7/PSME1/IRAK4/PSMB9/IRAK3/PSMA3/RPS6KA4/PSMA1/PSMB2/PSMB3/PSMA8/UBB/PSME4/PSMB5/PELI2/ZNF675/PELI3/PSMF1	31
BP	GO:0045444	fat cell differentiation	54/2306	223/18670	7.01e-07	0.0001238	9.523e-05	BMP2/ZC3H12A/PTGS2/IL6/ID2/TRIB2/CEBPD/PPARGC1A/CEBPB/PSMB8/ARID5B/FOXO1/WWTR1/SOCS1/CMKLR1/ARL4A/FTO/SORT1/CCND1/KLF4/ZFP36/NUDT7/MSX2/STK4/TRIB3/TCF7L2/ZFP36L2/NOC3L/INHBB/ENPP1/ARNTL/RGS2/TMEM64/SNAI2/BBS2/WNT5B/LRP5/CARM1/CLIP3/FNDC5/MMP11/SIRT1/WNT5A/TNF/SH3PXD2B/CEBPA/GATA3/DUSP10/PPARG/FGF10/GDF6/ITGA6/TBL1XR1/FAM120B	54
BP	GO:0071219	cellular response to molecule of bacterial origin	52/2306	212/18670	7.357e-07	0.0001263	9.717e-05	CXCL1/CXCL2/CXCL6/NFKBIA/ZC3H12A/ICAM1/TNFAIP3/IRAK2/CCL5/IL6/CXCL5/CSF2/IL1B/RIPK2/CXCL10/NFKB1/CCL2/TRIB1/ABCA1/PPARGC1A/CEBPB/PRKCA/PDCD1LG2/TNFRSF1B/TNIP3/PF4V1/NFKBIB/IL12A/CXCL3/CMPK2/PDE4D/CXCL11/CCL3/ZFP36/CXCL9/SIRPA/LDOC1/AXL/MEF2C/WNT5A/ABCC2/AKAP8/HAVCR2/TNF/ASS1/CHMP5/SERPINE1/ABL1/BCL10/PDE4B/TICAM1/CAPN2	52
BP	GO:2000736	regulation of stem cell differentiation	34/2306	116/18670	8.629e-07	0.0001412	0.0001087	PSME2/PSMA6/CDK6/PSMB10/PSMB8/PSMB7/PSME1/BMP4/PSMB9/MYB/TCF12/PSMA3/ITCH/LBH/ZFP36L2/SOX5/TGFB2/GATA6/YAP1/PSMA1/PSMB2/PSMB3/HES5/TACSTD2/PUS7/TRIM6/GATA3/PSMA8/ABL1/PSME4/PSMB5/STAT3/PSMF1/CBFB	34
BP	GO:0045071	negative regulation of viral genome replication	22/2306	59/18670	8.684e-07	0.0001412	0.0001087	ZC3H12A/CCL5/TNIP1/MX1/ISG20/CCL8/OAS1/ISG15/OAS3/IFITM1/RSAD2/PLSCR1/IFIT1/APOBEC3G/OASL/EIF2AK4/APOBEC3H/FAM111A/TNF/TRIM6/APOBEC3F/BTBD17	22
BP	GO:0048660	regulation of smooth muscle cell proliferation	44/2306	169/18670	9.183e-07	0.0001455	0.000112	SOD2/AKR1B1/TNFAIP3/NAMPT/CCL5/PTGS2/IL6/ID2/TRIB1/ERN1/PPARGC1A/NPR3/FGF2/STAT1/EREG/IRAK4/BMP4/PAK1/PDGFRB/IL12A/MYB/PDE1A/KLF4/CYBA/THBS1/IL15/EDN1/TCF7L2/HBEGF/PDGFD/ITGA2/MMP9/MEF2C/HES5/FOXJ2/MIR137/TNF/MIR1-2/MIR214/PPARG/CDKN1A/MNAT1/IGF1/SERPINF2	44
BP	GO:0042326	negative regulation of phosphorylation	94/2306	468/18670	1.035e-06	0.0001578	0.0001214	ZC3H12A/TNFAIP3/BDKRB1/TNIP1/PID1/IL1B/LIF/BDKRB2/TRIB1/ADORA2A/HSPB1/TRIB2/PARP14/PPARGC1A/CNKSR3/GPD1L/FOXO1/GPRC5A/DUSP6/CORO1C/DNAJA1/BMP4/WWTR1/SOCS1/SOCS3/COX11/PPIF/DUSP14/IRAK3/CALM1/SLIT2/PDE4D/NR2F2/LATS2/MYADM/KLF4/ADAR/GBP1/ITCH/UBASH3B/PIK3R2/PTPN13/CYLD/TRIB3/ENPP1/SEMA4D/SIRPA/KAT2B/RGS2/DNAJC3/SPRY1/SMYD3/ERRFI1/HEXIM2/PDE12/DNAJC15/DUSP3/LRP5/CDKN2C/SIRT1/RGS4/RGN/CDKN1C/MIR137/DYNLL1/CALM2/RNF149/CEBPA/SPINK1/DUSP16/PRKCD/ANKLE2/ADARB1/ITPRIP/GMFB/ABL1/DUSP18/DUSP10/PER1/PKIG/CTDSP2/CDKN1A/EPHA1/ENG/DUSP5/SH3RF2/CBLB/MIR218-1/STAT3/DVL1/P2RX7/CRKL/SIRT6/ZNF675	94
BP	GO:0043500	muscle adaptation	35/2306	122/18670	1.047e-06	0.0001578	0.0001214	IL1B/PPARGC1A/PRKCA/JARID2/TNFRSF1B/FOXO1/IL6ST/ROCK1/CFLAR/PAK1/CAMK2D/KLF4/LMNA/CYBA/LMCD1/IL15/EDN1/RGS2/GATA6/ERRFI1/MEF2C/MIR19B2/RGS4/GSN/CAMK2G/ATP2A2/MIR1-2/PPP3CA/ROCK2/MIR214/MYH6/NPPA/PDE5A/MIR199A2/IGF1	35
BP	GO:0071229	cellular response to acid chemical	51/2306	209/18670	1.105e-06	0.0001627	0.0001251	ZC3H12A/PID1/CLDN1/ABCA1/PPARGC1A/CEBPB/SIX1/SESN1/VEGFA/KLF2/MYB/SOCS1/PTGFR/COL1A1/FYN/IRS1/PKD2/KLF4/CYBA/EDN1/PTGER2/COL5A2/SH3BP4/PDGFD/CPT1A/ACACA/SESN3/WNT5B/YAP1/UBR1/WNT5A/BCL2L1/AKAP8/SESN2/TNC/PTK7/TNF/ASS1/FZD4/PDGFC/COL16A1/COL4A1/CPS1/PDK3/COL1A2/PPARG/ID3/OSR1/FZD7/CAPN2/GNG2	51
BP	GO:0035455	response to interferon-alpha	12/2306	21/18670	1.226e-06	0.0001762	0.0001356	IFNAR2/IFNAR1/MX2/IFITM1/ADAR/IFIT3/PDE12/AXL/IFIT2/KLHL20/GATA3/GAS6	12
BP	GO:0002819	regulation of adaptive immune response	42/2306	160/18670	1.275e-06	0.0001782	0.0001371	NFKBIZ/ZC3H12A/TNFAIP3/IL6/IL1B/RIPK2/IL33/IRF1/IL7R/TNFRSF14/RSAD2/C3/TNFRSF1B/IL6ST/IRF7/TNFSF13B/HLA-E/IL12A/IL18R1/IL4R/HLA-F/CD40/FADD/HLA-A/ADA/EXOSC6/EIF2AK4/ADCY7/CLCF1/STAT6/MEF2C/SIRT1/TRAF2/HAVCR2/TNF/GATA3/HLA-G/DUSP10/P2RX7/HLA-B/SASH3/HLA-H	42
BP	GO:0048659	smooth muscle cell proliferation	44/2306	171/18670	1.298e-06	0.0001782	0.0001371	SOD2/AKR1B1/TNFAIP3/NAMPT/CCL5/PTGS2/IL6/ID2/TRIB1/ERN1/PPARGC1A/NPR3/FGF2/STAT1/EREG/IRAK4/BMP4/PAK1/PDGFRB/IL12A/MYB/PDE1A/KLF4/CYBA/THBS1/IL15/EDN1/TCF7L2/HBEGF/PDGFD/ITGA2/MMP9/MEF2C/HES5/FOXJ2/MIR137/TNF/MIR1-2/MIR214/PPARG/CDKN1A/MNAT1/IGF1/SERPINF2	44
BP	GO:0031032	actomyosin structure organization	49/2306	199/18670	1.347e-06	0.000181	0.0001392	ASAP3/ROCK1/ARHGEF10/CFLAR/CNN2/PAK1/PDGFRB/PPFIA1/ITGB5/EPB41L4B/ARHGAP28/ACTC1/EDN1/PXN/MYOM1/EPB41L3/LPAR1/FHOD1/SIX4/CNN3/MEF2C/PHLDB2/FRMD3/MYO18A/MYOM3/PFN2/ARHGEF5/SH3PXD2B/TACSTD2/MIR1-2/EPB41L1/KRT19/SDC4/ZYX/ABL1/ROCK2/EPHA1/TMOD2/MYH6/CDC42/MYH9/EPB41L4A/MYH10/ACTG1/SERPINF2/CASQ1/PDCD6IP/WASF2/EPB41L2	49
BP	GO:0045088	regulation of innate immune response	91/2306	452/18670	1.382e-06	0.0001817	0.0001398	NFKBIA/BIRC3/TNFAIP3/IRAK2/CCL5/TNIP1/PSME2/RELB/RIPK2/NFKB1/PSMA6/PSMB10/IRF1/PARP14/IFIH1/IFNAR2/IFNGR1/BIRC2/PSMB8/RSAD2/PSMB7/IFNGR2/PSME1/PLSCR1/TNIP3/STAT1/EREG/DDX60/IRAK4/IRF7/PAK1/CTSS/TRAF3/GBP5/HLA-E/PSMB9/IL12A/SOCS1/SOCS3/TSPAN6/HLA-F/IRAK3/FYN/TIFA/DDX58/PSMA3/ADAR/FADD/CYBA/ITCH/CYLD/MAP3K1/DHX58/DMBT1/RAB11FIP2/FLOT1/PSMA1/PARP9/PSMB2/POLR3D/WNT5A/WDFY1/PSMB3/MICB/HAVCR2/SLAMF8/APPL2/TRAFD1/TLR3/TRIM6/PRKCD/PSMA8/HLA-G/RTN4/LGR4/NCR1/BCL10/DUSP10/USP18/UBB/MUC15/PPARG/MUC17/PTPN11/ZBP1/PSME4/PJA2/TICAM1/PSMB5/ADAM8/PSMF1	91
BP	GO:0022604	regulation of cell morphogenesis	96/2306	484/18670	1.422e-06	0.0001831	0.0001409	ICAM1/CCL2/ZSWIM4/CCL7/KIT/NTN1/PDPN/ZFYVE27/SIPA1L1/DBN1/CAPRIN1/CORO1C/VEGFA/EEF2K/PAK1/CDC42EP1/ARHGAP18/MOV10/CD44/FYN/NEDD9/CDC42EP3/SLIT2/RHOJ/BMPR2/MYADM/LIMS2/CCL3/RUFY3/MKLN1/SHROOM3/GBP1/NEUROG3/WTIP/RDX/SEMA4D/EPB41L3/RHOB/SDC2/FMNL2/FGD4/LPAR1/CHN1/GNA13/HECW2/RHOBTB3/HAS2/FGD1/GNA12/RHOU/PLEKHO1/IFRD1/SH3D19/ROBO1/ITPKA/ARPC2/CDK5/WNT5A/BHLHB9/SYT4/EPS8/PDLIM5/YWHAH/SPARC/TACSTD2/BRSK2/ACTN4/FERMT2/FZD4/DLG4/PLXND1/GDI1/DIAPH1/SYT1/RTN4/PPP3CA/ABL1/ZNF135/MYO10/YTHDF1/VAMP7/ACTR2/CDC42/MYH9/SEMA4F/MYH10/CDH4/DVL1/DVL2/MYCBP2/ZMYM1/NEDD4/NGEF/ANKRD27/CRKL/CAMSAP1	96
BP	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	26/2306	79/18670	1.496e-06	0.0001857	0.0001428	PSME2/TAP1/TAP2/PSMA6/PSMB10/PSMB8/PSMB7/PSME1/HLA-E/PSMB9/HLA-F/ITGB5/PSMA3/CYBA/HLA-A/PSMA1/PSMB2/PSMB3/PSMA8/HLA-G/TAPBP/PSME4/PSMB5/HLA-B/HLA-H/PSMF1	26
BP	GO:0060070	canonical Wnt signaling pathway	72/2306	335/18670	1.516e-06	0.0001857	0.0001428	BMP2/PSME2/NFKB1/PSMA6/PSMB10/NDP/DAB2/RECK/PSMB8/PSMB7/PSME1/FOXO1/MCC/ANKRD6/LZTS2/NKD2/PSMB9/WWTR1/FZD1/COL1A1/LATS2/KLF4/PSMA3/CYLD/SULF2/STK4/UBR5/TCF7L2/DIXDC1/FZD2/ARNTL/MITF/TMEM64/CSNK1G2/SNAI2/WNT5B/YAP1/CSNK1E/LRP5/DAAM2/PSMA1/FZD8/PSMB2/DACT3/MIR19B2/WNT5A/VPS35/PSMB3/PTK7/SOX7/MIR1-2/FZD4/RSPO2/JRK/GATA3/TCF7L1/PSMA8/LGR4/MYH6/FGF10/TLE1/PSME4/FERMT1/PSMB5/DVL1/DVL2/CSNK1G3/TBL1XR1/FZD7/SDHAF2/PLEKHA4/PSMF1	72
BP	GO:0045785	positive regulation of cell adhesion	83/2306	403/18670	1.557e-06	0.0001857	0.0001428	NFKBIZ/ICAM1/CCL5/IL6/CYTH3/CD70/VCAM1/MAP3K8/IL1B/CD83/RIPK2/CCL2/NINJ1/CDK6/CSF1/TNFSF9/CITED2/IL7R/PRKCA/PDPN/TNFRSF14/PDCD1LG2/IL6ST/VEGFA/ROCK1/TNFSF13B/PAK1/HLA-E/IL12A/MYB/IL4R/SOCS1/CD44/FYN/NEDD9/ETS1/EPB41L4B/MYADM/LIMS2/STX3/ANK3/FADD/ITGA4/IL15/CYLD/ADA/PODXL/SIRPA/CCDC80/TGFB2/EBI3/ITGA2/RSU1/HAS2/ZFHX3/FLOT1/EFNB1/ARPC2/WNT5A/HSD17B12/HAVCR2/TNF/TFE3/GATA3/COL16A1/HLA-G/PPP3CA/SDC4/ABL1/BCL10/DUSP10/MYO10/PTPN11/EPHA1/CDC42/FERMT1/IGF1/ITGA6/SERPINF2/SASH3/ADAM8/CRKL/CBFB	83
BP	GO:0048871	multicellular organismal homeostasis	96/2306	485/18670	1.562e-06	0.0001857	0.0001428	AKR1B1/TNFAIP3/PTGS2/IL6/IL1B/SLC11A2/CLDN1/HSPB1/DIO2/IL1A/PPARGC1A/CSF1/LPIN1/CEBPB/NPR3/PRKCA/EPAS1/FOXO1/G0S2/VEGFA/TP53INP2/ACACB/WWTR1/LDB2/IL18R1/IL4R/LIPA/CMKLR1/FTO/IRX3/UGCG/CHMP4B/SCD/AMPD3/SGIP1/IL15/UBASH3B/OXTR/KRT16/HADH/CYTL1/ARNTL/F2R/ADCY7/RAB11FIP2/ACACA/TMEM64/THRA/FH/BBS2/YAP1/ADIPOR2/ADCY9/HAS2/ADCY3/STAT6/GADD45G/ARRDC3/ADORA1/RCN3/TP63/MRAP2/ABAT/ACTB/TNF/BGLAP/APPL2/CLN8/TFE3/PDGFC/IAPP/ADRB3/PRKAB2/ZNF830/LGR4/SCNN1A/UBB/PCDH15/PTPN11/ANKRD11/TNFRSF11B/FLG/SERPINA3/STAT3/ACTG1/P2RX7/SASH3/ADAM8/HOMER2/SIRT6/ZNF675/CRTC3/ELOVL3/TFF1/POTEF/SNX10	96
BP	GO:0001101	response to acid chemical	73/2306	343/18670	1.883e-06	0.0002191	0.0001686	AKR1B1/ZC3H12A/ICAM1/PTGS2/PID1/CLDN1/PTGES/ABCA1/PPARGC1A/CEBPB/SIX1/FOXO1/SESN1/INSIG2/VEGFA/GIP/KLF2/PDGFRB/MYB/SOCS1/PTGFR/COL1A1/FYN/FABP3/RXRA/IRS1/PKD2/KLF4/SCD/CYBA/EDN1/PTGER2/COL5A2/SH3BP4/PDGFD/CPT1A/ACACA/ITGA2/SESN3/GJB2/WNT5B/YAP1/UBR1/IGF2R/LRP11/WNT5A/ABCC2/ATG7/BCL2L1/AKAP8/SESN2/TNC/MICB/GSN/PTK7/TNF/ASS1/SPARC/FZD4/ASNS/PDGFC/COL16A1/COL4A1/CPS1/PDK3/COL1A2/PPARG/ID3/OSR1/FZD7/GDAP2/CAPN2/GNG2	73
BP	GO:0043900	regulation of multi-organism process	83/2306	405/18670	1.914e-06	0.0002191	0.0001686	CXCL6/BIRC3/ZC3H12A/TNFAIP3/CCL5/TNIP1/IL1B/MX1/RIPK2/TRIB1/ISG20/CCL8/OAS1/BIRC2/ISG15/PRKCA/FBXL2/OAS3/IFITM1/RSAD2/PLSCR1/STAT1/DDX60/TRAF3/IFIT1/APOBEC3G/TSPAN6/TRIM25/DDX58/CHMP4B/TRAF3IP2/CCL3/ADAR/CYBA/ITCH/ZFP36/OASL/IL15/OXTR/ADA/EIF2AK4/DHX58/APOBEC3H/INHBB/LHFPL2/PPIA/PDE12/IGF2R/PARP9/NOX5/OPTN/PABPC1/TRIM21/FAM111A/MICB/RAD23A/GSN/DDX5/HAVCR2/TNF/HERC5/STAU1/ZP2/STXBP1/SPINK1/TRIM6/PTX3/ADARB1/NPR2/APOBEC3F/ZNF639/NUCKS1/ARHGDIB/KPNA2/BTBD17/PKN2/PDE5A/TRIM38/IGF1/P2RX7/GTF2F2/MAPKBP1/SNX3	83
BP	GO:1903901	negative regulation of viral life cycle	27/2306	85/18670	2.066e-06	0.0002321	0.0001786	ZC3H12A/CCL5/TNIP1/MX1/ISG20/CCL8/OAS1/ISG15/OAS3/IFITM1/RSAD2/PLSCR1/IFIT1/APOBEC3G/TRIM25/OASL/EIF2AK4/APOBEC3H/TRIM21/FAM111A/GSN/TNF/TRIM6/PTX3/APOBEC3F/BTBD17/SNX3	27
BP	GO:0032479	regulation of type I interferon production	35/2306	126/18670	2.378e-06	0.0002599	2e-04	TNFAIP3/RELB/RIPK2/NFKB1/NFKB2/IRF1/IFIH1/UBE2L6/ISG15/STAT1/IRF7/TRAF3/TRIM25/DDX58/POLR3GL/ITCH/UBA7/CYLD/DHX58/SIRPA/STAT6/FLOT1/POLR3D/TRIM21/HAVCR2/HERC5/TLR3/LRRFIP1/TAX1BP1/POLR3K/PTPN11/ZBP1/TICAM1/POLR1C/TRIM38	35
BP	GO:0045926	negative regulation of growth	57/2306	249/18670	2.397e-06	0.0002599	2e-04	MT1G/BDKRB1/MT1M/MT1E/MT1A/MT1X/MT2A/MT1H/MT1F/OSGIN2/NTN1/FHL1/MEIS1/JARID2/BMP4/PAK1/RERG/WWC1/NDRG3/SLIT2/BMPR2/STK4/CYP27B1/CRYAB/PPT1/SH3BP4/ENPP1/SEMA4D/DCBLD2/PPP1R9B/TGFB2/RGS2/TCHP/BBS2/ADIPOR2/SMARCA2/SERTAD2/IFRD1/CDKN2C/DACT3/CDK5/SIRT1/WNT5A/RGS4/GDF15/SESN2/MIR1-2/SOCS2/RTN4/DUSP10/PPARG/CDKN1A/NPPA/SEMA4F/MIR199A2/TSPYL2/ST20	57
BP	GO:0036293	response to decreased oxygen levels	77/2306	370/18670	2.443e-06	0.0002603	0.0002003	BMP2/ICAM1/NAMPT/PTGS2/VCAM1/PSME2/SLC11A2/PSMA6/PSMB10/PPARGC1A/ARNT2/CITED2/BIRC2/DDAH1/PSMB8/PSMB7/PSME1/EPAS1/SLC2A1/VEGFA/EEF2K/AGTRAP/HK2/CFLAR/PAK1/TBL2/PSMB9/MYB/PLAU/ETS1/PSMA3/LMNA/CYBA/THBS1/WTIP/FMN2/OXTR/ADA/EDN1/EGLN1/CRYAB/PMAIP1/HIPK2/ERCC2/TGFB2/ITGA2/GATA6/PLOD2/CYGB/PSMA1/ASCL2/ITPR2/PSMB2/SIRT1/ADORA1/NKX3-1/PSMB3/ACAA2/ABAT/P2RX3/HMOX2/PGF/HYOU1/ACTN4/PSMA8/PDK3/ROCK2/MIR214/UBB/NPPA/PSME4/FAM162A/PSMB5/CLCA1/ADAM8/CAPN2/PSMF1	77
BP	GO:0048661	positive regulation of smooth muscle cell proliferation	30/2306	101/18670	2.755e-06	0.0002886	0.000222	AKR1B1/NAMPT/CCL5/PTGS2/IL6/ID2/ERN1/PPARGC1A/FGF2/STAT1/EREG/IRAK4/BMP4/PAK1/PDGFRB/MYB/CYBA/THBS1/EDN1/HBEGF/PDGFD/ITGA2/MMP9/HES5/FOXJ2/TNF/MIR214/MNAT1/IGF1/SERPINF2	30
BP	GO:0030522	intracellular receptor signaling pathway	62/2306	280/18670	2.862e-06	0.0002897	0.0002229	NFKBIA/BIRC3/TNFAIP3/IRAK2/RIPK2/IFIH1/PPARGC1A/CITED2/DAB2/BIRC2/DAXX/AHR/DNAJA1/DDX60/IRF7/PAK1/TSPAN6/RXRA/TIFA/NR2F2/DDX58/ITCH/RNF14/FHL2/PIM1/DHRS3/CYLD/DHX58/LBH/UBR5/CYP27B1/ARNTL/DCBLD2/THRA/SNAI2/YAP1/CARM1/VDR/SIRT1/NKX3-1/TP63/DDX5/RNF4/YWHAH/ACTN4/KCTD6/GPAM/ARID1A/UFSP2/NCOR2/PDK3/UBB/PER1/PPARG/STAT3/FAM120B/CDK7/NEDD4/CRKL/TADA3/NCOA6/CBFB	62
BP	GO:1902036	regulation of hematopoietic stem cell differentiation	24/2306	72/18670	2.906e-06	0.0002897	0.0002229	PSME2/PSMA6/CDK6/PSMB10/PSMB8/PSMB7/PSME1/PSMB9/MYB/TCF12/PSMA3/ITCH/YAP1/PSMA1/PSMB2/PSMB3/PUS7/GATA3/PSMA8/ABL1/PSME4/PSMB5/PSMF1/CBFB	24
BP	GO:0051546	keratinocyte migration	11/2306	19/18670	2.91e-06	0.0002897	0.0002229	IQSEC1/EPB41L4B/KRT16/HBEGF/HAS2/MMP9/ARF6/KRT2/MAPRE2/FGF10/FERMT1	11
BP	GO:0022407	regulation of cell-cell adhesion	82/2306	403/18670	2.953e-06	0.0002897	0.0002229	NFKBIZ/BMP2/ZC3H12A/ICAM1/CCL5/IL6/CD70/VCAM1/MAP3K8/IL1B/CD83/RIPK2/CCL2/ADORA2A/IRF1/TNFSF9/CITED2/CEBPB/C1QTNF1/IL7R/PRKCA/PDPN/TNFRSF14/PDCD1LG2/IDO1/IL6ST/VEGFA/BMP4/TNFSF13B/PAK1/HLA-E/IL12A/MYB/IL4R/SOCS1/CD44/FYN/ETS1/LRRC32/MYADM/KLF4/ANK3/FADD/ITGA4/IL15/UBASH3B/CYLD/ADA/RDX/MBP/PODXL/MAD1L1/SIRPA/EBI3/SNAI2/HAS2/DUSP3/FLOT1/EFNB1/WNT5A/ABAT/HAVCR2/TNF/ASS1/GATA3/PRKCD/HLA-G/SDC4/ABL1/BCL10/DUSP10/MYO10/PTPN11/CDC42/PDE5A/IGF1/ITGA6/SERPINF2/SASH3/ADAM8/AKNA/CBFB	82
BP	GO:0001933	negative regulation of protein phosphorylation	86/2306	429/18670	3.196e-06	0.0002997	0.0002306	ZC3H12A/TNFAIP3/BDKRB1/TNIP1/PID1/IL1B/LIF/BDKRB2/TRIB1/ADORA2A/HSPB1/TRIB2/PARP14/PPARGC1A/CNKSR3/GPD1L/FOXO1/GPRC5A/DUSP6/CORO1C/DNAJA1/BMP4/WWTR1/SOCS1/SOCS3/DUSP14/IRAK3/CALM1/SLIT2/PDE4D/NR2F2/LATS2/MYADM/KLF4/ADAR/GBP1/ITCH/UBASH3B/PIK3R2/PTPN13/CYLD/TRIB3/ENPP1/SEMA4D/SIRPA/KAT2B/RGS2/DNAJC3/SPRY1/SMYD3/ERRFI1/HEXIM2/DUSP3/LRP5/CDKN2C/SIRT1/RGS4/RGN/CDKN1C/MIR137/CALM2/RNF149/CEBPA/SPINK1/DUSP16/PRKCD/ADARB1/ITPRIP/GMFB/ABL1/DUSP18/DUSP10/PER1/PKIG/CTDSP2/CDKN1A/EPHA1/ENG/DUSP5/SH3RF2/CBLB/MIR218-1/DVL1/P2RX7/CRKL/ZNF675	86
BP	GO:0001505	regulation of neurotransmitter levels	74/2306	354/18670	3.214e-06	0.0002997	0.0002306	ZC3H12A/ICAM1/PTGS2/IL1B/SLC7A2/ADORA2A/DDAH1/SLC22A2/SLC7A11/KLF2/PPFIA1/PNKD/ARL6IP5/PKD2/KLF4/STX3/BACE1/GCH1/GLA/EDN1/SRD5A1/RAB3GAP1/PPT1/HNMT/SIRPA/PRG3/RGS2/MOXD1/LIN7A/FLOT1/MEF2C/DAGLA/CDK5/RGS4/SNAP47/RAB3A/RGN/SYT4/AMT/ALDH7A1/PREPL/PFN2/SLC30A1/ABAT/DGKI/TNF/CACNA1B/ASS1/RPH3A/CLN8/ATP2A2/DAGLB/SNPH/STXBP1/DDAH2/ALDH5A1/PTX3/PHGDH/SYT1/CPS1/GRIN3A/ROCK2/HBB/SLC22A3/TOR1A/TICAM1/NAPB/MIR199A2/DVL1/LIN7C/P2RX7/PPFIA3/SLC29A1/SLC38A1	74
BP	GO:0072001	renal system development	64/2306	293/18670	3.231e-06	0.0002997	0.0002306	BMP2/AKR1B1/LIF/ID2/AHI1/BASP1/FGF2/ARID5B/NFIA/PLCE1/SIX1/STAT1/KLHL3/VEGFA/LZTS2/CFLAR/BMP4/PDGFRB/WWTR1/RDH10/SLIT2/IRX3/NUP133/PKD2/FADD/HOXA11/ACAT1/SULF2/MYO1E/BMPER/PODXL/PDGFD/TGFB2/SPRY1/YAP1/HAS2/MMP9/CEP290/SIX4/MMP17/MEF2C/WNT5A/NKX3-1/SULF1/RGN/HES5/CDKN1C/FBN1/PGF/ASS1/TACSTD2/OSR2/GCNT1/GATA3/COL4A1/HOXB7/C1GALT1/SDC4/LGR4/TMED10/ID3/FGF10/ITGA6/OSR1	64
BP	GO:0070997	neuron death	73/2306	348/18670	3.275e-06	0.0002997	0.0002306	SOD2/BID/NAMPT/CCL5/ITGA1/CCL2/ADORA2A/PPARGC1A/CSF1/CEBPB/NCOA7/DAXX/SIX1/TNFRSF1B/SLC7A11/ROCK1/MYB/FZD1/SET/LANCL1/HLA-F/FYN/CHMP4B/BACE1/CCL3/NRBP2/SSH1/FADD/PPT1/UBE2M/HIPK2/F2R/TGFB2/CLCF1/GDF5/SIX4/POLB/AXL/MEF2C/CDK5/SIRT1/WNT5A/TRAF2/ADORA1/ATG7/KCNB1/VPS35/BHLHB9/BCL2L1/TP63/BTG2/TRIM2/TNF/HYOU1/MIR125B1/STXBP1/GATA3/USP53/ADARB1/OXR1/ABL1/EN2/UBB/MAX/SIGMAR1/BTBD10/FAM162A/RILPL1/ATP13A2/STAT3/ADAM8/CAPN2/PICALM	73
BP	GO:0009896	positive regulation of catabolic process	85/2306	423/18670	3.297e-06	0.0002997	0.0002306	ZC3H12A/TNFAIP3/IL6/IL1B/RIPK2/IL33/TRIB1/TRIB2/BAG2/DAB2/TNFRSF1B/FOXO1/DAPK1/SESN1/TP53INP2/HK2/ROCK1/PLK2/NKD2/ANKIB1/PLEKHF1/MOV10/PIM2/FTO/HERPUD1/IRS1/NUB1/DDA1/ITCH/RNF14/ZFP36/TRIB3/EIF2AK4/RDX/RAB3GAP1/ZFP36L2/SH3BP4/ARIH2/CPT1A/TP53INP1/SESN3/HECW2/CSNK1E/ABCD1/SH3D19/ARIH1/ASB5/SIRT1/OPTN/WNT5A/PABPC1/ADORA1/ATG7/VPS35/TRIM21/RNF144B/TPCN1/RGN/CAMKK2/BTG2/SESN2/PAFAH1B2/RAD23A/TNF/CNOT8/ABHD5/CEBPA/DET1/PRKCD/MAGEF1/ROCK2/PIP4K2A/TICAM1/SH3RF2/FBXL5/IGF1/DVL1/P2RX7/MYLIP/NEDD4/ADAM8/ZFAND2A/OSBPL7/ST20/ADRA2A	85
BP	GO:0001655	urogenital system development	70/2306	330/18670	3.438e-06	0.0003079	0.0002369	BMP2/AKR1B1/LIF/ID2/AHI1/BASP1/FGF2/ARID5B/NFIA/PLCE1/SIX1/STAT1/KLHL3/VEGFA/LZTS2/CFLAR/BMP4/PDGFRB/WWTR1/RDH10/RXRA/SLIT2/IRX3/NUP133/PKD2/FADD/HOXA11/ACAT1/SULF2/MYO1E/BMPER/SRD5A1/PODXL/PDGFD/TGFB2/SPRY1/YAP1/HAS2/MMP9/CEP290/SIX4/MMP17/MEF2C/WNT5A/NKX3-1/SULF1/RGN/TP63/HES5/CDKN1C/TNC/FBN1/PGF/ASS1/TACSTD2/OSR2/GCNT1/GATA3/COL4A1/HOXB7/C1GALT1/SDC4/LGR4/TMED10/ID3/FGF10/ITGA6/OSR1/CYP19A1/CRKL	70
BP	GO:0032606	type I interferon production	35/2306	128/18670	3.52e-06	0.0003108	0.0002391	TNFAIP3/RELB/RIPK2/NFKB1/NFKB2/IRF1/IFIH1/UBE2L6/ISG15/STAT1/IRF7/TRAF3/TRIM25/DDX58/POLR3GL/ITCH/UBA7/CYLD/DHX58/SIRPA/STAT6/FLOT1/POLR3D/TRIM21/HAVCR2/HERC5/TLR3/LRRFIP1/TAX1BP1/POLR3K/PTPN11/ZBP1/TICAM1/POLR1C/TRIM38	35
BP	GO:0035567	non-canonical Wnt signaling pathway	39/2306	150/18670	3.871e-06	0.000337	0.0002592	PSME2/PSMA6/PSMB10/DAB2/PSMB8/PSMB7/PSME1/ANKRD6/PSMB9/FZD1/GPC4/MOV10/CALM1/PSMA3/TCF7L2/ROR1/FZD2/CLTC/CSNK1E/DAAM2/PSMA1/FZD8/PSMB2/WNT5A/PSMB3/PTK7/FZD4/PSMA8/PPP3CA/ABL1/PSME4/CDC42/PSMB5/DVL1/DVL2/FZD7/PLEKHA4/PSMF1/GNG2	39
BP	GO:0060071	Wnt signaling pathway, planar cell polarity pathway	31/2306	108/18670	4.189e-06	0.0003595	0.0002766	PSME2/PSMA6/PSMB10/DAB2/PSMB8/PSMB7/PSME1/ANKRD6/PSMB9/FZD1/GPC4/PSMA3/ROR1/FZD2/CLTC/PSMA1/PSMB2/WNT5A/PSMB3/PTK7/FZD4/PSMA8/ABL1/PSME4/CDC42/PSMB5/DVL1/DVL2/FZD7/PLEKHA4/PSMF1	31
BP	GO:0051090	regulation of DNA-binding transcription factor activity	86/2306	432/18670	4.264e-06	0.000361	0.0002778	NFKBIA/ZC3H12A/ICAM1/TNFAIP3/IRAK2/IL6/IL1B/RIPK2/NFKB1/ID2/PSMA6/NFKB2/TRIB1/NDP/PPARGC1A/KIT/NFKBIE/ARID5B/VEGFA/IRAK4/CFLAR/TRAF3/IL18R1/FZD1/CMKLR1/TRIM25/CD40/IRAK3/DDX58/PKD2/KLF4/TRIM37/NEUROG3/ITCH/PIM1/MSX2/CYLD/EDN1/EIF2AK4/EGLN1/TCF7L2/CYTL1/ROR1/FZD2/ENPP1/HIPK2/RPS6KA4/FLOT1/CARM1/SIRT1/MIR19B2/WNT5A/TRAF2/NKX3-1/ANXA4/TRIM21/RIPK4/ARHGEF5/HAVCR2/TNF/MIR1-2/FZD4/SP100/TLR3/PPP3CA/LRRFIP1/TAX1BP1/RBCK1/BCL10/UBB/GAS6/PPARG/PYDC2/ID3/SIK1/TICAM1/TRAPPC9/TRIM38/STAT3/DVL2/SRI/ADAM8/ADORA3/SGK3/ZNF675/CRTC3	86
BP	GO:0019932	second-messenger-mediated signaling	87/2306	439/18670	4.532e-06	0.0003756	0.000289	CCL20/VCAM1/MT2A/PPP3CC/CXCL10/ADORA2A/ABCA1/DDAH1/PRKCA/PLCE1/AHR/VEGFA/GIP/GSTO1/PTGFR/CMKLR1/CALM1/P2RY11/PDE4D/CAMK2D/PKD2/CXCL11/RASD1/CCL3/GBP1/THBS1/FHL2/DYRK2/LMCD1/ADA/EDN1/PTGER2/PTHLH/CXCL9/DMPK/ADM2/MC1R/ADCY7/PPP1R9B/SGCD/RGS2/LPAR1/GNA13/NDUFS4/ADCY9/ADCY3/RCAN1/ITPR2/ARRDC3/TMBIM4/RGN/CAMKK2/RAMP1/MRAP2/P2RX3/TNF/GPR161/CALM2/ATP2A2/MIR1-2/FKBP1A/IAPP/DDAH2/ADRB3/SPINK1/PPP3CA/LGR4/NPR2/SAMD14/PDE3B/MCOLN1/KSR1/NPPA/NMUR2/RCAN2/PDE5A/IGF1/CCR10/SRI/P2RX7/HINT1/CASQ1/HOMER2/ADRA2A/CHP2/CRTC3/GNG2	87
BP	GO:0042180	cellular ketone metabolic process	56/2306	248/18670	4.558e-06	0.0003756	0.000289	BMP2/AKR1B1/PTGS2/CBR3/PSME2/IL1B/PSMA6/PSMB10/PPARGC1A/PSMB8/KYNU/PSMB7/PSME1/INSIG2/IDO1/SLC7A11/GIP/ACACB/PSMB9/AFP/ELOVL5/RDH10/FABP3/PNKD/COQ10B/IRS1/NFE2L1/PSMA3/TRIB3/SRD5A1/CPT1A/CBR4/ADIPOR2/AADAT/PDSS2/UBIAD1/PSMA1/ABCD1/PSMB2/HAGH/SIRT1/COQ3/RGN/PSMB3/APPL2/PRKAB2/LONP2/PSMA8/NCOR2/PDK3/PPARG/PSME4/PSMB5/MID1IP1/CYP19A1/PSMF1	56
BP	GO:0001666	response to hypoxia	74/2306	359/18670	5.462e-06	0.0004441	0.0003417	BMP2/ICAM1/PTGS2/VCAM1/PSME2/SLC11A2/PSMA6/PSMB10/PPARGC1A/ARNT2/CITED2/BIRC2/DDAH1/PSMB8/PSMB7/PSME1/EPAS1/SLC2A1/VEGFA/AGTRAP/HK2/CFLAR/PAK1/TBL2/PSMB9/MYB/PLAU/ETS1/PSMA3/LMNA/CYBA/THBS1/WTIP/FMN2/ADA/EDN1/EGLN1/CRYAB/PMAIP1/HIPK2/ERCC2/TGFB2/ITGA2/GATA6/PLOD2/CYGB/PSMA1/ASCL2/ITPR2/PSMB2/SIRT1/ADORA1/NKX3-1/PSMB3/ACAA2/ABAT/P2RX3/HMOX2/PGF/HYOU1/ACTN4/PSMA8/PDK3/ROCK2/MIR214/UBB/NPPA/PSME4/FAM162A/PSMB5/CLCA1/ADAM8/CAPN2/PSMF1	74
BP	GO:0031668	cellular response to extracellular stimulus	59/2306	268/18670	5.96e-06	0.0004783	0.000368	ZC3H12A/ICAM1/NAMPT/PTGS2/VCAM1/XPR1/FOXO1/SESN1/GABARAPL1/SLC2A1/SLC38A2/TBL2/COL1A1/FYN/P2RY11/BMPR2/FAS/SSH1/WIPI1/ITGA4/CYBA/IL15/PIM1/EIF2AK4/GSDMD/SRD5A1/CYP27B1/INHBB/FNIP1/PMAIP1/PPP1R9B/NUDT1/SNAI2/SESN3/DNAJC15/AXL/VDR/SIRT1/ATG7/KCNB1/SESN2/TNC/P2RX3/BGLAP/PPM1D/MIR125B1/ASNS/GLRX2/KPTN/WDR45/PDXP/GAS6/MAX/PPARG/CDKN1A/SIK1/ITGA6/P2RX7/MYBBP1A	59
BP	GO:0055076	transition metal ion homeostasis	35/2306	131/18670	6.202e-06	0.0004914	0.0003781	SLC39A14/MT1G/MT1M/MT1E/MT1A/MT1X/SLC11A2/MT2A/ACO1/MT1H/MT1F/STEAP1/EPAS1/SLC25A28/FTH1/SLC25A37/SLC39A10/NDFIP1/SLC39A8/SLC30A9/CAND1/SLC30A7/ABCG2/ARF1/SLC30A1/CUTC/HMOX2/CYBRD1/BDH2/FTHL17/STEAP2/FBXL5/ATP13A2/SRI/PICALM	35
BP	GO:0090175	regulation of establishment of planar polarity	31/2306	110/18670	6.355e-06	0.0004971	0.0003825	PSME2/PSMA6/PSMB10/DAB2/PSMB8/PSMB7/PSME1/ANKRD6/PSMB9/FZD1/GPC4/PSMA3/ROR1/FZD2/CLTC/PSMA1/PSMB2/WNT5A/PSMB3/PTK7/FZD4/PSMA8/ABL1/PSME4/CDC42/PSMB5/DVL1/DVL2/FZD7/PLEKHA4/PSMF1	31
BP	GO:0007249	I-kappaB kinase/NF-kappaB signaling	59/2306	269/18670	6.731e-06	0.00052	4e-04	NFKBIA/BIRC3/ZC3H12A/TNFAIP3/IRAK2/TNIP1/IL1B/RELB/RIPK2/HSPB1/SQSTM1/BIRC2/TNIP3/STAT1/ROCK1/IRAK4/PLK2/CFLAR/TSPAN6/TRIM25/CD40/FYN/PIM2/TIFA/TRAF3IP2/FADD/NDFIP1/ROR1/SIRPA/F2R/CXXC5/LPAR1/TIAF1/BCL3/SIRT1/OPTN/WNT5A/TRAF2/TNF/TNFRSF10B/IRAK1BP1/FKBP1A/UBD/TLR3/NEK6/ABL1/RBCK1/ROCK2/BCL10/UBB/PER1/NDFIP2/TLE1/TICAM1/TRIM38/TMEM101/MAPKBP1/PELI2/ZNF675	59
BP	GO:0061687	detoxification of inorganic compound	10/2306	17/18670	6.905e-06	0.0005206	0.0004005	MT1G/MT1M/MT1E/MT1A/MT1X/MT2A/MT1H/MT1F/ABCC2/SLC30A1	10
BP	GO:1901532	regulation of hematopoietic progenitor cell differentiation	26/2306	85/18670	6.907e-06	0.0005206	0.0004005	PSME2/PSMA6/CDK6/PSMB10/PSMB8/PSMB7/PSME1/PSMB9/MYB/TCF12/PSMA3/ITCH/FNIP1/YAP1/PSMA1/PSMB2/PSMB3/HES5/PUS7/GATA3/PSMA8/ABL1/PSME4/PSMB5/PSMF1/CBFB	26
BP	GO:0007015	actin filament organization	80/2306	400/18670	7.617e-06	0.0005662	0.0004356	ICAM1/PLS3/FSCN1/ASAP3/ARPC1A/DBN1/CORO1C/ROCK1/ARHGEF10/PAK1/PPFIA1/CDC42EP1/CGNL1/ARHGAP18/LIMA1/ACTR3/NEDD9/CDC42EP3/SLIT2/RHOJ/ITGB5/MYADM/RUFY3/SHROOM3/ARHGAP28/FMN2/ACTC1/RDX/PXN/MYOM1/DPYSL3/DSTN/RHOB/PPP1R9B/PLEKHH2/LPAR1/RHOBTB3/TTC17/FHOD1/RHOU/TPM4/PHLDB2/ARPC2/RGS4/ENAH/CAPZA2/ARF6/SHROOM2/MICAL3/ARF1/MYOM3/PFN2/ARHGEF5/EPS8/GSN/BIN3/SH3PXD2B/TACSTD2/ACTN4/CAP2/DIAPH1/PRKCD/SDC4/ZYX/KPTN/GMFB/ABL1/SAMD14/ROCK2/MIR214/PDXP/EPHA1/ACTR2/TMOD2/CDC42/SERPINF2/PLEKHG2/MAGEL2/WASF2/PDLIM3	80
BP	GO:0001819	positive regulation of cytokine production	90/2306	464/18670	7.696e-06	0.0005662	0.0004356	BIRC3/PTGS2/IL6/CSF2/IL1B/CD83/RIPK2/IL33/NFKB1/NFKB2/HSPB1/IRF1/IL1A/IFIH1/CEBPB/IFNGR1/BIRC2/TNFRSF14/RSAD2/C3/IDO1/STAT1/IL6ST/PANX1/EREG/DDX60/IRF7/GBP5/HLA-E/IL12A/IL18R1/MYB/IL4R/TSPAN6/HLA-F/CD58/CD40/PDE4D/DDX58/IL26/PANX2/POLR3GL/CCL3/FADD/CYBA/THBS1/IL15/IL17RB/SULF2/MAPK13/DHX58/AKAP12/GSDMD/MBP/F2R/CCL1/PRG3/EBI3/STAT6/FLOT1/BCL3/POLR3D/WNT5A/TRAF2/SULF1/HAVCR2/TNF/IL12RB2/TLR3/TRIM6/GATA3/HLA-G/LRRFIP1/SERPINE1/ABL1/ROCK2/BCL10/PDE4B/POLR3K/PTPN11/ZBP1/TICAM1/POLR1C/FERMT1/STAT3/P2RX7/SERPINF2/SASH3/ADAM8/ADRA2A	90
BP	GO:0003012	muscle system process	90/2306	465/18670	8.41e-06	0.0006114	0.0004704	ZC3H12A/PTGS2/IL1B/ITGA1/BDKRB2/PPARGC1A/KIT/PRKCA/GPD1L/JARID2/PLCE1/TNFRSF1B/FOXO1/IL6ST/MYOF/ROCK1/CFLAR/PAK1/VCL/GSTO1/CALD1/CALM1/ITGB5/PDE4D/CAMK2D/KLF4/LMNA/CYBA/LMCD1/MYL5/IL15/OXTR/ADA/ACTC1/SULF2/EDN1/CRYAB/PXN/DMPK/MYOM1/F2R/SGCD/RGS2/ITGA2/GATA6/ERRFI1/BBS2/SYNM/HCN4/GAMT/TPM4/MEF2C/STAC/MIR19B2/RGS4/ADORA1/SULF1/MYOM3/MYLK/GSN/ABAT/P2RX3/PDLIM5/CAMK2G/CALM2/CHRNB1/ATP2A2/MIR1-2/DOCK4/ATP8A2/PPP3CA/SNTA1/ROCK2/MIR214/PDE4B/KCND3/TMOD2/MYH6/NPPA/SNTB1/NMUR2/PDE5A/MIR199A2/IGF1/SRI/TLN1/MYL12A/CASQ1/KCNB2/ADRA2A	90
BP	GO:0002244	hematopoietic progenitor cell differentiation	41/2306	166/18670	8.776e-06	0.0006307	0.0004852	HERC6/PSME2/PSMA6/CDK6/PSMB10/CEBPD/KIT/PSMB8/PSMB7/PSME1/BMP4/JAM3/PDGFRB/PSMB9/MYB/EML1/TCF12/PSMA3/ADAR/ITCH/WDR7/FNIP1/ERCC2/YAP1/PSMA1/WDR78/PSMB2/PSMB3/HES5/PUS7/MLF1/GATA3/FST/PSMA8/ABL1/PSME4/PSMB5/SSBP3/PSMF1/TMEM91/CBFB	41
BP	GO:2001236	regulation of extrinsic apoptotic signaling pathway	39/2306	155/18670	9.019e-06	0.0006402	0.0004925	BID/ICAM1/TNFAIP3/CSF2/IL1B/SH3RF1/IL1A/G0S2/CFLAR/BMP4/PPP2R1B/FYN/FAS/LMNA/FADD/THBS1/CYLD/STK4/TCF7L2/PMAIP1/SNAI2/YAP1/DEDD2/TRAF2/BCL2L1/TNF/TNFRSF10B/SP100/BIRC6/ITPRIP/SERPINE1/RBCK1/BCL10/FGF10/IGF1/ITGA6/EYA2/SGK3/PELI3	39
BP	GO:0010038	response to metal ion	74/2306	364/18670	9.116e-06	0.0006402	0.0004925	ICAM1/MT1G/PTGS2/MT1M/MT1E/MT1A/SLC25A24/MT1X/VCAM1/SLC11A2/MT2A/CLDN1/PTGES/ID2/ACO1/MT1H/MT1F/IL1A/PPARGC1A/KIT/DAXX/AQP9/EEF2K/ANXA11/KRT14/PPIF/CALM1/CAMK2D/NFE2L1/PKD2/CCND1/BACE1/ANK3/THBS1/EDN1/TRPC1/ADCY7/NUDT1/CYP1A2/CYB5A/MMP9/CPNE3/MEF2C/ATF1/JUNB/WNT5A/ABCC2/SYT4/SLC30A1/XRCC4/GSN/ABAT/BGLAP/ASS1/CALM2/SPARC/CYBRD1/EIF2B5/DLG4/STIM1/GDI1/CEBPA/SYT1/CPS1/PPP3CA/MCOLN1/MNAT1/TNFRSF11B/ATP13A2/P2RX7/NEDD4/CUTA/CHP2/TFF1	74
BP	GO:0097191	extrinsic apoptotic signaling pathway	51/2306	224/18670	9.344e-06	0.0006488	0.0004992	BID/ICAM1/TNFAIP3/CD70/CSF2/IL1B/IL33/SH3RF1/IL1A/DAXX/TNFRSF1B/G0S2/DAPK1/CFLAR/BMP4/PPP2R1B/IL12A/BCL2L2/FYN/SORT1/FAS/LMNA/FADD/THBS1/CYLD/MKNK2/STK4/TCF7L2/PMAIP1/TGFB2/SNAI2/YAP1/DEDD2/TRAF2/BCL2L1/TNF/TNFRSF10B/SP100/BIRC6/TLR3/ITPRIP/SERPINE1/RBCK1/BCL10/FGF10/IGF1/ITGA6/P2RX7/EYA2/SGK3/PELI3	51
BP	GO:0071216	cellular response to biotic stimulus	53/2306	236/18670	9.571e-06	0.00065	0.0005001	CXCL1/CXCL2/CXCL6/NFKBIA/ZC3H12A/ICAM1/TNFAIP3/IRAK2/CCL5/IL6/CXCL5/CSF2/IL1B/RIPK2/CXCL10/NFKB1/CCL2/TRIB1/ABCA1/PPARGC1A/CEBPB/PRKCA/PDCD1LG2/TNFRSF1B/TNIP3/PF4V1/NFKBIB/IL12A/CXCL3/CMPK2/PDE4D/CXCL11/CCL3/ZFP36/CXCL9/SIRPA/LDOC1/AXL/MEF2C/WNT5A/ABCC2/AKAP8/HAVCR2/TNF/ASS1/IGFBPL1/CHMP5/SERPINE1/ABL1/BCL10/PDE4B/TICAM1/CAPN2	53
BP	GO:0001822	kidney development	60/2306	278/18670	9.572e-06	0.00065	0.0005001	BMP2/AKR1B1/LIF/ID2/AHI1/BASP1/FGF2/ARID5B/PLCE1/SIX1/STAT1/KLHL3/VEGFA/LZTS2/CFLAR/BMP4/PDGFRB/WWTR1/RDH10/SLIT2/IRX3/NUP133/PKD2/FADD/HOXA11/ACAT1/SULF2/MYO1E/BMPER/PODXL/PDGFD/TGFB2/SPRY1/YAP1/HAS2/MMP9/CEP290/SIX4/MMP17/MEF2C/NKX3-1/SULF1/RGN/HES5/CDKN1C/FBN1/PGF/ASS1/TACSTD2/OSR2/GCNT1/GATA3/HOXB7/C1GALT1/SDC4/LGR4/TMED10/ID3/FGF10/OSR1	60
BP	GO:0006882	cellular zinc ion homeostasis	15/2306	36/18670	9.874e-06	0.0006633	0.0005103	SLC39A14/MT1G/MT1M/MT1E/MT1A/MT1X/MT2A/MT1H/MT1F/SLC39A10/SLC39A8/SLC30A9/SLC30A7/SLC30A1/ATP13A2	15
BP	GO:0033209	tumor necrosis factor-mediated signaling pathway	41/2306	167/18670	1.026e-05	0.000682	0.0005247	NFKBIA/BIRC3/TNFAIP3/CD70/PSME2/PSMA6/PSMB10/TNFSF9/BIRC2/PSMB8/TNFRSF14/PSMB7/TNFRSF9/PSME1/TNFRSF1B/STAT1/TNFSF13B/TRAF3/PSMB9/CD40/PSMA3/CYLD/PSMA1/CLIP3/PSMB2/TRAF2/PSMB3/TNF/ACTN4/PSMA8/TAX1BP1/RBCK1/GAS6/PYDC2/PSME4/TNFRSF11B/PSMB5/PIAS3/ZNF675/PELI3/PSMF1	41
BP	GO:0019058	viral life cycle	68/2306	328/18670	1.058e-05	0.0006861	0.0005279	ZC3H12A/ICAM1/CCL5/TNIP1/CLDN1/MX1/CCL2/ISG20/CCL8/OAS1/CHMP1B/ANPEP/ISG15/FBXL2/OAS3/XPR1/IFITM1/TNFRSF14/RSAD2/NFIA/PLSCR1/SLC20A2/IFIT1/APOBEC3G/TRIM25/EPS15/ITGB5/NUP133/CHMP4B/ADAR/ITCH/OASL/EIF2AK4/APOBEC3H/VPS37D/VPS37C/ITGA2/PPIA/PDE12/KPNA3/AXL/PABPC1/TRIM21/FAM111A/RAD23A/GSN/DDX5/TNF/STAU1/TRIM6/PTX3/ADARB1/CHMP5/APOBEC3F/ZNF639/ROCK2/NUCKS1/UBB/GAS6/KPNA2/BTBD17/PKN2/NUP35/CDC42/TRIM38/PDCD6IP/NMT2/SNX3	68
BP	GO:0060759	regulation of response to cytokine stimulus	45/2306	190/18670	1.061e-05	0.0006861	0.0005279	BIRC3/TNFAIP3/IRAK2/CCL5/IL6/RIPK2/PARP14/IFIH1/CSF1/IFNAR2/IFNGR1/BIRC2/IFNGR2/STAT1/IRF7/SOCS1/SOCS3/IRAK3/SLIT2/DDX58/KLF4/ADAR/FADD/CYLD/EDN1/PARP9/CLIP3/AXL/ROBO1/WNT5A/TRAF2/TNF/MIR125B1/TRIM6/TAX1BP1/RBCK1/USP18/GAS6/PPARG/PTPN11/ZBP1/PYDC2/ZNF675/PELI3/CBFB	45
BP	GO:0007517	muscle organ development	81/2306	410/18670	1.077e-05	0.0006861	0.0005279	BMP2/MAFF/LIF/CXCL10/MSC/PITX1/BASP1/FHL1/FGF2/MEIS1/JARID2/ARID5B/SIX1/CFLAR/BMP4/PAK1/POPDC2/FZD1/TCF12/RXRA/SAP30/NR2F2/PIM1/ACTC1/EDN1/FGFRL1/CRYAB/MYOM1/FZD2/HBEGF/ARNTL/SGCD/TGFB2/RGS2/SRPK3/GATA6/YAP1/HOXD9/ZFHX3/FLNB/FLOT1/MEOX2/SIX4/MEF2C/AKIRIN1/CDK5/SIRT1/MIR19B2/WNT5A/RGS4/ITGA11/COL6A3/BTG2/MYOM3/MYLK/DDX5/BIN3/ASS1/SGCG/ETV1/MIR1-2/FKBP1A/ADARB1/PPP3CA/ASB2/CHKB/MYH6/ENG/ID3/UBE4B/MIR199A2/IGF1/SRI/CASQ1/FZD7/SGCB/FOXO4/DNER/SIRT6/VAMP5/CD164	81
BP	GO:0019216	regulation of lipid metabolic process	81/2306	410/18670	1.077e-05	0.0006861	0.0005279	BMP2/PTGS2/IL1B/NFKB1/ID2/ABCA1/PPARGC1A/KIT/FGF2/C3/G0S2/INSIG2/GIP/PLIN2/PDGFRB/ACACB/ELOVL5/SOCS1/NPAS2/SOCS3/RDH10/RAB38/FABP3/RXRA/IRS1/NFE2L1/KLF4/SCD/DDX20/EDF1/IDH1/SMARCD3/FHL2/PIK3R2/TRIB3/CYP27B1/TM7SF2/CPT1A/ACACA/PIK3R3/THRA/SNAI2/ADIPOR2/DNAJC15/CARM1/ABCD1/VDR/SIRT1/ADORA1/TNFAIP8L3/RGN/ARF1/TNF/APPL2/TIAM2/ALAS1/ABHD5/SOCS2/GPAM/PRKAB2/PRKCD/LONP2/ME1/WDR91/NCOR2/PDK3/PDE3B/NSMAF/PPARG/IDI1/SIK1/SERPINA3/SIN3B/TBL1XR1/SAMD8/ACADM/MID1IP1/CAPN2/NCOA6/ADRA2A/CRTC3	81
BP	GO:0022409	positive regulation of cell-cell adhesion	56/2306	255/18670	1.097e-05	0.0006918	0.0005323	NFKBIZ/ICAM1/CCL5/IL6/CD70/VCAM1/MAP3K8/IL1B/CD83/RIPK2/CCL2/TNFSF9/CITED2/IL7R/PDPN/TNFRSF14/PDCD1LG2/IL6ST/TNFSF13B/PAK1/HLA-E/IL12A/MYB/IL4R/SOCS1/CD44/FYN/ETS1/ANK3/FADD/ITGA4/IL15/CYLD/ADA/PODXL/SIRPA/EBI3/HAS2/FLOT1/EFNB1/WNT5A/HAVCR2/TNF/GATA3/HLA-G/BCL10/DUSP10/MYO10/PTPN11/CDC42/IGF1/ITGA6/SERPINF2/SASH3/ADAM8/CBFB	56
BP	GO:0043434	response to peptide hormone	85/2306	436/18670	1.117e-05	0.0006976	0.0005367	ICAM1/PTGS2/PID1/IL1B/NFKB1/STAT4/LPIN1/FOXO1/PTPRE/INSIG2/SLC2A1/STAT1/EREG/EEF2K/AGTRAP/GIP/ROCK1/CFLAR/ATP6V1E2/RAB13/PAK1/SOCS1/SOCS3/COL1A1/ATP6V0B/FYN/FABP3/SORT1/IRS1/GRB14/TBC1D4/ATP6V0E2/CYBA/OXTR/PIK3R2/TRIB3/EDN1/HADH/SRD5A1/PXN/INHBB/ENPP1/GHR/ADCY7/PIK3R3/KAT2B/STAT2/ERRFI1/SESN3/GJB2/ADCY9/ADCY3/STAT6/SIRT1/ABCC2/GDF15/BTG2/SESN2/TIMP4/FBN1/BGLAP/ASS1/APPL2/SPARC/EIF2B5/EIF2B4/GCNT1/SOCS2/PRKCD/CPS1/ROCK2/NUCKS1/PDE3B/MAX/SLC25A33/AP3S1/PPARG/PTPN11/NCOA5/NPPA/STAT3/RAB31/ATP6V1E1/FOXO4/TFF1	85
BP	GO:0030177	positive regulation of Wnt signaling pathway	43/2306	179/18670	1.134e-05	0.0007002	0.0005387	BMP2/TNFAIP3/PSME2/NFKB1/PSMA6/PSMB10/DAB2/RECK/PSMB8/PSMB7/PSME1/ANKRD6/PSMB9/COL1A1/PSMA3/SULF2/UBR5/DIXDC1/ARNTL/CSNK1G2/YAP1/CSNK1E/DAAM2/PSMA1/PSMB2/WNT5A/VPS35/SULF1/PSMB3/PTK7/RSPO2/JRK/PSMA8/LGR4/ABL1/FGF10/SPIN1/PSME4/PSMB5/CSNK1G3/TBL1XR1/PLEKHA4/PSMF1	43
BP	GO:1903706	regulation of hemopoiesis	91/2306	475/18670	1.144e-05	0.0007002	0.0005387	NFKBIZ/NFKBIA/ZC3H12A/CSF2/PSME2/LIF/CD83/RIPK2/ID2/PSMA6/SH3RF1/TRIB1/CDK6/PSMB10/IRF1/CSF1/TNFSF9/CEBPB/ISG15/MEIS1/PSMB8/IL7R/PRKCA/MAFB/PSMB7/PSME1/STAT1/BMP4/IRF7/PSMB9/IL12A/MYB/IL4R/SOCS1/TCF12/MOV10/ETS1/PSMA3/CCL3/FADD/ITCH/THBS1/ZFP36/IL15/PIM1/UBASH3B/CYLD/ADA/PRMT1/ZFP36L2/FNIP1/KAT2B/KLF13/MITF/TMEM64/YAP1/PURB/PSMA1/ACIN1/AXL/MEF2C/PSMB2/PSMB3/HES5/FBN1/TNF/BGLAP/SLAMF8/PUS7/RBM15/MIR125B1/HOXA9/TFE3/RBBP5/TLR3/GATA3/PSMA8/HLA-G/PRDM1/ABL1/DUSP10/GAS6/PSME4/PSMB5/STAT3/SASH3/ADAM8/PIAS3/ZNF675/PSMF1/CBFB	91
BP	GO:0060828	regulation of canonical Wnt signaling pathway	61/2306	286/18670	1.193e-05	0.0007228	0.0005561	BMP2/PSME2/NFKB1/PSMA6/PSMB10/DAB2/RECK/PSMB8/PSMB7/PSME1/FOXO1/MCC/ANKRD6/LZTS2/NKD2/PSMB9/WWTR1/FZD1/COL1A1/LATS2/PSMA3/CYLD/SULF2/STK4/UBR5/TCF7L2/ARNTL/TMEM64/CSNK1G2/SNAI2/WNT5B/YAP1/CSNK1E/DAAM2/PSMA1/PSMB2/DACT3/MIR19B2/WNT5A/VPS35/PSMB3/PTK7/SOX7/MIR1-2/RSPO2/JRK/PSMA8/LGR4/FGF10/TLE1/PSME4/FERMT1/PSMB5/DVL1/DVL2/CSNK1G3/TBL1XR1/FZD7/SDHAF2/PLEKHA4/PSMF1	61
BP	GO:0001736	establishment of planar polarity	33/2306	124/18670	1.234e-05	0.0007333	0.0005642	PSME2/PSMA6/PSMB10/DAB2/PSMB8/PSMB7/PSME1/ANKRD6/PSMB9/FZD1/GPC4/PSMA3/ROR1/FZD2/CLTC/PSMA1/PSMB2/WNT5A/TP63/PSMB3/PTK7/BRSK2/FZD4/PSMA8/ABL1/PSME4/CDC42/PSMB5/DVL1/DVL2/FZD7/PLEKHA4/PSMF1	33
BP	GO:0007164	establishment of tissue polarity	33/2306	124/18670	1.234e-05	0.0007333	0.0005642	PSME2/PSMA6/PSMB10/DAB2/PSMB8/PSMB7/PSME1/ANKRD6/PSMB9/FZD1/GPC4/PSMA3/ROR1/FZD2/CLTC/PSMA1/PSMB2/WNT5A/TP63/PSMB3/PTK7/BRSK2/FZD4/PSMA8/ABL1/PSME4/CDC42/PSMB5/DVL1/DVL2/FZD7/PLEKHA4/PSMF1	33
BP	GO:0050688	regulation of defense response to virus	23/2306	73/18670	1.343e-05	0.0007864	0.0006051	BIRC3/ZC3H12A/TNFAIP3/IL1B/BIRC2/STAT1/DDX60/TRAF3/IFIT1/APOBEC3G/TSPAN6/DDX58/TRAF3IP2/ITCH/IL15/EIF2AK4/DHX58/PARP9/MICB/HERC5/TRIM6/APOBEC3F/TRIM38	23
BP	GO:0006979	response to oxidative stress	87/2306	451/18670	1.349e-05	0.0007864	0.0006051	SOD2/ZC3H12A/TNFAIP3/PTGS2/IL6/SLC25A24/GPR37L1/HSPB1/MMP3/PPARGC1A/NCOA7/ACOX2/EPAS1/FOXO1/DAPK1/SESN1/STAT1/SLC7A11/CFLAR/KLF2/PDGFRB/MYB/FZD1/COL1A1/PPIF/LANCL1/FYN/ETS1/NFE2L1/ARL6IP5/PKD2/KLF4/NET1/IDH1/CYBA/GCH1/SCARA3/ADA/EDN1/MAPK13/EGLN1/CRYAB/PXN/ARNTL/PDGFD/SIRPA/RHOB/ERCC2/TP53INP1/NME5/NUDT1/SESN3/GJB2/STAT6/CYGB/MMP9/ABCD1/AXL/NOX5/SIRT1/TRAF2/ABCC2/ATG7/RGN/CAMKK2/ADPRHL2/MTR/SESN2/TXN/MICB/PRKRA/TNF/HMOX2/CLN8/ATP2A2/STAU1/PRKCD/GLRX2/OXR1/ABL1/HBB/TOR1A/SIGMAR1/PTGS1/PSMB5/ATP13A2/CAPN2	87
BP	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	82/2306	419/18670	1.37e-05	0.0007914	0.0006089	PSME2/IL33/PSMA6/TRIB1/PSMB10/TRIB2/DAB2/BIRC2/PSMB8/FBXL2/PSMB7/PSME1/PLK2/NKD2/RAD23B/PSMB9/WWTR1/UBE4A/ANKIB1/TRIM25/HERPUD1/DNAJB9/NUB1/CDC16/PSMA3/DDA1/ITCH/RNF14/FBXL6/TRIB3/NCCRP1/ARNTL/SDCBP/ARIH2/MAP1A/HECW2/UBR1/CSNK1E/GNA12/PSMA1/ARIH1/SPSB1/PSMB2/RNF5/SIRT1/ARAF/RNF144B/CRBN/UBE2E1/PSMB3/TRIM2/RAD23A/RNF4/UBXN1/FBXW4/FBXL22/TOPORS/USP14/KLHL20/CEBPA/DET1/PSMA8/FBXO17/RBCK1/PPP2R5C/UBB/PSME4/SH3RF2/FBXL5/PSMB5/TRIM38/CDC23/UBE4B/DVL1/TBL1XR1/RNF121/RNF126/NEDD4/ZFAND2A/BFAR/UBE2S/PSMF1	82
BP	GO:0060218	hematopoietic stem cell differentiation	25/2306	83/18670	1.39e-05	0.0007934	0.0006104	PSME2/PSMA6/CDK6/PSMB10/PSMB8/PSMB7/PSME1/PSMB9/MYB/TCF12/PSMA3/ITCH/ERCC2/YAP1/PSMA1/PSMB2/PSMB3/PUS7/GATA3/PSMA8/ABL1/PSME4/PSMB5/PSMF1/CBFB	25
BP	GO:0045089	positive regulation of innate immune response	76/2306	381/18670	1.403e-05	0.0007934	0.0006104	NFKBIA/BIRC3/TNFAIP3/IRAK2/CCL5/TNIP1/PSME2/RELB/RIPK2/NFKB1/PSMA6/PSMB10/IRF1/IFIH1/BIRC2/PSMB8/RSAD2/PSMB7/PSME1/PLSCR1/TNIP3/EREG/DDX60/IRAK4/IRF7/PAK1/CTSS/TRAF3/GBP5/HLA-E/PSMB9/IL12A/TSPAN6/HLA-F/IRAK3/FYN/TIFA/DDX58/PSMA3/FADD/CYBA/ITCH/CYLD/MAP3K1/DHX58/DMBT1/RAB11FIP2/FLOT1/PSMA1/PARP9/PSMB2/POLR3D/WNT5A/WDFY1/PSMB3/MICB/HAVCR2/APPL2/TLR3/TRIM6/PRKCD/PSMA8/HLA-G/RTN4/LGR4/BCL10/UBB/MUC15/MUC17/ZBP1/PSME4/PJA2/TICAM1/PSMB5/ADAM8/PSMF1	76
BP	GO:0043405	regulation of MAP kinase activity	69/2306	337/18670	1.412e-05	0.0007934	0.0006104	BMP2/IRAK2/MAP3K8/IL1B/RIPK2/ITGA1/TRIB1/ERN1/TRIB2/TPD52L1/KIT/FGF2/DAXX/PLCE1/DUSP6/VEGFA/DNAJA1/BMP4/PAK1/PDGFRB/DUSP14/CD40/IRAK3/THBS1/KIDINS220/MAP3K1/TRIB3/EDN1/TGFA/GHR/PDGFD/F2R/RGS2/SPRY1/LPAR1/DUSP3/GADD45G/ROBO1/FZD8/WNT5A/RGS4/TRAF2/ADORA1/GDF15/ARHGEF5/TNF/MAP3K2/MLKL/FZD4/PDGFC/DUSP16/PRKCD/DUSP18/DUSP10/UBB/KSR1/PTPN11/FGF10/DUSP5/PDE5A/IGF1/MIR218-1/DVL2/P2RX7/TAOK1/ADAM8/CRKL/ZNF675/ADRA2A	69
BP	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	29/2306	104/18670	1.56e-05	0.0008685	0.0006682	ICAM1/TNFAIP3/CSF2/IL1B/SH3RF1/IL1A/CFLAR/BMP4/FYN/FAS/LMNA/FADD/THBS1/TCF7L2/SNAI2/YAP1/TRAF2/BCL2L1/TNF/TNFRSF10B/BIRC6/ITPRIP/SERPINE1/FGF10/IGF1/ITGA6/EYA2/SGK3/PELI3	29
BP	GO:0002483	antigen processing and presentation of endogenous peptide antigen	9/2306	15/18670	1.637e-05	0.0008951	0.0006886	TAP1/TAP2/HLA-E/HLA-F/HLA-A/HLA-G/TAPBP/HLA-B/HLA-H	9
BP	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	9/2306	15/18670	1.637e-05	0.0008951	0.0006886	TAP1/TAP2/HLA-E/HLA-F/HLA-A/HLA-G/TAPBP/HLA-B/HLA-H	9
BP	GO:0051549	positive regulation of keratinocyte migration	8/2306	12/18670	1.67e-05	0.0009055	0.0006967	IQSEC1/EPB41L4B/HBEGF/HAS2/MMP9/ARF6/MAPRE2/FGF10	8
BP	GO:0006469	negative regulation of protein kinase activity	52/2306	235/18670	1.786e-05	0.00096	0.0007386	TNFAIP3/IL1B/TRIB1/ADORA2A/HSPB1/TRIB2/GPRC5A/DUSP6/CORO1C/DNAJA1/BMP4/WWTR1/SOCS1/SOCS3/DUSP14/IRAK3/NR2F2/LATS2/ADAR/UBASH3B/TRIB3/KAT2B/RGS2/DNAJC3/SPRY1/SMYD3/ERRFI1/HEXIM2/DUSP3/LRP5/CDKN2C/SIRT1/RGS4/RGN/CDKN1C/CEBPA/DUSP16/PRKCD/ADARB1/ITPRIP/GMFB/ABL1/DUSP18/DUSP10/PKIG/CDKN1A/EPHA1/DUSP5/CBLB/MIR218-1/DVL1/ZNF675	52
BP	GO:0002821	positive regulation of adaptive immune response	29/2306	105/18670	1.904e-05	0.001014	0.0007803	NFKBIZ/IL6/IL1B/RIPK2/RSAD2/C3/IL6ST/TNFSF13B/HLA-E/IL12A/IL18R1/HLA-F/CD40/FADD/HLA-A/ADA/EXOSC6/EIF2AK4/CLCF1/STAT6/SIRT1/TRAF2/TNF/GATA3/HLA-G/P2RX7/HLA-B/SASH3/HLA-H	29
BP	GO:0045598	regulation of fat cell differentiation	34/2306	132/18670	1.948e-05	0.001026	0.0007897	BMP2/ZC3H12A/PTGS2/IL6/ID2/TRIB2/CEBPB/FOXO1/WWTR1/CMKLR1/FTO/SORT1/ZFP36/MSX2/STK4/TRIB3/ZFP36L2/ENPP1/ARNTL/TMEM64/SNAI2/WNT5B/LRP5/CARM1/FNDC5/MMP11/SIRT1/WNT5A/TNF/SH3PXD2B/CEBPA/GATA3/DUSP10/PPARG	34
BP	GO:0001959	regulation of cytokine-mediated signaling pathway	42/2306	177/18670	1.96e-05	0.001026	0.0007897	BIRC3/TNFAIP3/IRAK2/CCL5/IL6/RIPK2/PARP14/CSF1/IFNAR2/IFNGR1/BIRC2/IFNGR2/STAT1/IRF7/SOCS1/SOCS3/IRAK3/SLIT2/ADAR/FADD/CYLD/EDN1/PARP9/CLIP3/AXL/ROBO1/WNT5A/TRAF2/TNF/MIR125B1/TRIM6/TAX1BP1/RBCK1/USP18/GAS6/PPARG/PTPN11/ZBP1/PYDC2/ZNF675/PELI3/CBFB	42
BP	GO:1901653	cellular response to peptide	76/2306	385/18670	2.048e-05	0.001064	0.0008184	AKR1B1/ICAM1/NAMPT/VCAM1/PID1/IL1B/RIPK2/NFKB1/LPIN1/FOXO1/PTPRE/STAT1/EEF2K/AGTRAP/ROCK1/CFLAR/ATP6V1E2/RAB13/PAK1/KLF2/SOCS1/SOCS3/BCL2L2/ATP6V0B/FYN/IRS1/KLF4/BACE1/GRB14/TBC1D4/ATP6V0E2/ITGA4/CYBA/PIK3R2/TRIB3/EDN1/SRD5A1/PXN/INHBB/ENPP1/GHR/ADCY7/PIK3R3/KAT2B/ERRFI1/SESN3/LDOC1/GJB2/ADCY9/ADCY3/STAT6/CDK5/SIRT1/GDF15/FBN1/BGLAP/ASS1/APPL2/SOCS2/PRKCD/CPS1/CHMP5/ROCK2/NUCKS1/PDE3B/MAX/SLC25A33/AP3S1/PPARG/PTPN11/NCOA5/IGF1/STAT3/RAB31/ATP6V1E1/FOXO4	76
BP	GO:0001656	metanephros development	26/2306	90/18670	2.145e-05	0.001101	0.0008467	AKR1B1/LIF/ID2/BASP1/SIX1/STAT1/BMP4/PDGFRB/WWTR1/RDH10/IRX3/PKD2/HOXA11/ACAT1/SPRY1/YAP1/SIX4/NKX3-1/HES5/FBN1/OSR2/GATA3/LGR4/ID3/FGF10/OSR1	26
BP	GO:0055069	zinc ion homeostasis	15/2306	38/18670	2.155e-05	0.001101	0.0008467	SLC39A14/MT1G/MT1M/MT1E/MT1A/MT1X/MT2A/MT1H/MT1F/SLC39A10/SLC39A8/SLC30A9/SLC30A7/SLC30A1/ATP13A2	15
BP	GO:0010498	proteasomal protein catabolic process	90/2306	477/18670	2.344e-05	0.001188	0.0009136	PSME2/IL33/PSMA6/TRIB1/PSMB10/TRIB2/BAG2/DAB2/BIRC2/PSMB8/FBXL2/PSMB7/PSME1/PLK2/NKD2/RAD23B/PSMB9/WWTR1/UBE4A/ANKIB1/TRIM25/HERPUD1/DNAJB9/NFE2L1/NUB1/CDC16/PSMA3/DDA1/ENC1/ITCH/RNF14/FBXL6/TRIB3/NCCRP1/PMAIP1/ARNTL/SDCBP/ARIH2/MAP1A/HECW2/UBR1/CSNK1E/GNA12/PSMA1/ARIH1/SPSB1/PSMB2/RNF5/SIRT1/ARAF/RCN3/RNF144B/CRBN/UBE2E1/PSMB3/TRIM2/RAD23A/RNF4/UBXN1/FBXW4/FBXL22/TOPORS/USP14/BRSK2/KLHL20/CEBPA/DET1/PSMA8/FBXO17/RBCK1/PPP2R5C/UBB/TOR1A/PSME4/SH3RF2/FBXL5/PSMB5/TRIM38/CDC23/UBE4B/DVL1/TBL1XR1/RNF121/RNF126/NEDD4/ZFAND2A/BFAR/UBE2S/OSBPL7/PSMF1	90
BP	GO:0048754	branching morphogenesis of an epithelial tube	37/2306	150/18670	2.43e-05	0.001221	0.0009395	BMP2/CSF1/FGF2/SIX1/VEGFA/BMP4/PAK1/RDH10/SLIT2/PKD2/HOXA11/MSX2/STK4/EDN1/SPRY1/GNA13/YAP1/LRP5/SIX4/VDR/WNT5A/NKX3-1/TNC/TNF/PGF/TACSTD2/RBM15/RSPO2/PLXND1/COL4A1/HOXB7/LGR4/ABL1/ENG/FGF10/SIRT6/TBX3	37
BP	GO:0051235	maintenance of location	67/2306	330/18670	2.475e-05	0.001234	0.000949	NFKBIA/ZC3H12A/BDKRB1/IL6/IL1B/CXCL10/NFKB1/ABCA1/NFKBIE/FGF2/PLCE1/C3/DBN1/HK2/PLIN2/ACACB/GSTO1/CALM1/FTO/PDE4D/CAMK2D/PKD2/CXCL11/FTH1/CCL3/ANK3/CYBA/UBASH3B/CXCL9/ENPP1/GPSM2/EPB41L3/TRPC1/F2R/SLC30A7/SOAT1/FLNB/EHD1/BCL3/ITPR2/CDK5/SIRT1/SRGN/TPCN1/TXN/FBN1/GSN/TNF/CALM2/TOPORS/MIR1-2/SP100/ABHD5/FKBP1A/DIAPH1/ARHGAP21/ABL1/FTHL17/MCOLN1/PPARG/ARL2BP/SRI/P2RX7/TLN1/CASQ1/RER1/MORC3	67
BP	GO:0050792	regulation of viral process	47/2306	208/18670	2.525e-05	0.001248	0.0009605	ZC3H12A/CCL5/TNIP1/MX1/ISG20/CCL8/OAS1/ISG15/FBXL2/OAS3/IFITM1/RSAD2/PLSCR1/STAT1/IFIT1/APOBEC3G/TRIM25/CHMP4B/CCL3/ADAR/ZFP36/OASL/EIF2AK4/APOBEC3H/PPIA/PDE12/IGF2R/PABPC1/TRIM21/FAM111A/RAD23A/GSN/DDX5/TNF/STAU1/TRIM6/PTX3/ADARB1/APOBEC3F/ZNF639/NUCKS1/KPNA2/BTBD17/PKN2/TRIM38/GTF2F2/SNX3	47
BP	GO:1901214	regulation of neuron death	64/2306	313/18670	2.969e-05	0.001456	0.00112	SOD2/CCL5/ITGA1/CCL2/ADORA2A/PPARGC1A/CSF1/CEBPB/NCOA7/DAXX/SIX1/TNFRSF1B/SLC7A11/ROCK1/MYB/FZD1/SET/LANCL1/HLA-F/FYN/CHMP4B/BACE1/CCL3/NRBP2/SSH1/PPT1/UBE2M/HIPK2/F2R/TGFB2/CLCF1/GDF5/SIX4/AXL/MEF2C/CDK5/SIRT1/WNT5A/TRAF2/ADORA1/ATG7/KCNB1/VPS35/BHLHB9/BCL2L1/BTG2/TRIM2/TNF/HYOU1/MIR125B1/STXBP1/GATA3/OXR1/ABL1/EN2/UBB/SIGMAR1/BTBD10/RILPL1/ATP13A2/STAT3/ADAM8/CAPN2/PICALM	64
BP	GO:0002573	myeloid leukocyte differentiation	46/2306	204/18670	3.237e-05	0.001566	0.001205	MT1G/CSF2/RELB/LIF/ID2/TRIB1/CDK6/CSF1/KIT/CEBPB/PIK3CD/PRKCA/MAFB/VEGFA/BMP4/IRF7/CCL3/FADD/IL15/UBASH3B/MITF/TMEM64/BATF3/MMP9/ACIN1/MEF2C/SIRT1/JUNB/FBN1/TNF/BGLAP/MIR125B1/TFE3/UBD/TLR3/CEBPA/GATA3/PPARG/DHRS7B/CDC42/TSPAN2/MYH9/OSTM1/PIAS3/ZNF675/SNX10	46
BP	GO:0048872	homeostasis of number of cells	53/2306	246/18670	3.247e-05	0.001566	0.001205	CXCL6/TNFAIP3/IL6/SLC11A2/ID2/CDK6/CSF1/KIT/ISG15/PIK3CD/IL7R/MAFB/EPAS1/STAT1/SLC7A11/VEGFA/BMP4/TNFSF13B/JAM3/KLF2/LIPA/ETS1/NFE2L1/ADAR/FADD/AMPD3/ZFP36/CYLD/ADA/PRMT1/PMAIP1/HIPK2/F2R/ERCC2/KLF13/THRA/FH/ACIN1/POLB/AXL/MEF2C/CACNA1F/BAP1/GATA3/LGR4/ABL1/BCL10/PDE4B/PTPN11/STAT3/P2RX7/SASH3/ARID4A	53
BP	GO:1904894	positive regulation of STAT cascade	26/2306	92/18670	3.27e-05	0.001566	0.001205	AKR1B1/CCL5/IL6/CSF2/LIF/PARP14/KIT/IL7R/IL6ST/IL12A/SOCS1/SOCS3/CD40/FYN/IL26/IL15/GHR/F2R/CLCF1/PARP9/MIR19B2/HES5/TNF/IGF1/STAT3/ARL2BP	26
BP	GO:0010565	regulation of cellular ketone metabolic process	42/2306	181/18670	3.451e-05	0.001633	0.001256	BMP2/PTGS2/PSME2/IL1B/PSMA6/PSMB10/PPARGC1A/PSMB8/PSMB7/PSME1/INSIG2/SLC7A11/GIP/ACACB/PSMB9/ELOVL5/RDH10/FABP3/IRS1/NFE2L1/PSMA3/TRIB3/CPT1A/ADIPOR2/PSMA1/ABCD1/PSMB2/SIRT1/COQ3/RGN/PSMB3/APPL2/PRKAB2/LONP2/PSMA8/NCOR2/PDK3/PPARG/PSME4/PSMB5/MID1IP1/PSMF1	42
BP	GO:0034599	cellular response to oxidative stress	62/2306	302/18670	3.461e-05	0.001633	0.001256	SOD2/ZC3H12A/TNFAIP3/IL6/SLC25A24/GPR37L1/HSPB1/MMP3/PPARGC1A/NCOA7/EPAS1/FOXO1/DAPK1/SLC7A11/CFLAR/KLF2/MYB/FZD1/PPIF/LANCL1/FYN/ETS1/NFE2L1/ARL6IP5/PKD2/KLF4/NET1/CYBA/GCH1/MAPK13/PXN/ARNTL/PDGFD/SIRPA/RHOB/TP53INP1/NME5/GJB2/STAT6/MMP9/ABCD1/AXL/NOX5/SIRT1/TRAF2/ATG7/RGN/CAMKK2/ADPRHL2/MTR/SESN2/TXN/PRKRA/TNF/ATP2A2/STAU1/PRKCD/GLRX2/OXR1/ABL1/SIGMAR1/ATP13A2	62
BP	GO:0034350	regulation of glial cell apoptotic process	7/2306	10/18670	3.71e-05	0.001737	0.001337	CCL2/PRKCA/AKAP12/CDK5/TRAF2/PRKCD/GAS6	7
BP	GO:0061138	morphogenesis of a branching epithelium	42/2306	182/18670	3.959e-05	0.001839	0.001415	BMP2/CSF1/FGF2/SIX1/VEGFA/BMP4/PAK1/SOCS3/RDH10/RXRA/SLIT2/PKD2/HOXA11/MSX2/STK4/EDN1/SPRY1/GNA13/SNAI2/YAP1/LRP5/SIX4/VDR/WNT5A/NKX3-1/SULF1/TP63/TNC/TNF/PGF/TACSTD2/RBM15/RSPO2/PLXND1/COL4A1/HOXB7/LGR4/ABL1/ENG/FGF10/SIRT6/TBX3	42
BP	GO:0072006	nephron development	35/2306	142/18670	4.049e-05	0.001867	0.001437	BMP2/LIF/AHI1/BASP1/FGF2/PLCE1/SIX1/STAT1/KLHL3/VEGFA/LZTS2/CFLAR/BMP4/PDGFRB/WWTR1/IRX3/NUP133/PKD2/HOXA11/ACAT1/SULF2/MYO1E/PODXL/PDGFD/YAP1/SIX4/MEF2C/SULF1/HES5/PGF/TACSTD2/GATA3/HOXB7/LGR4/OSR1	35
BP	GO:0052548	regulation of endopeptidase activity	81/2306	425/18670	4.102e-05	0.001878	0.001445	BIRC3/BID/PTGS2/PSME2/SERPINA9/RIPK2/SERPINB2/SH3RF1/ADORA2A/SERPINB8/RECK/BIRC2/PSMB8/PRR7/PSME1/C3/DAPK1/TNFAIP8/PDCD5/VEGFA/CFLAR/PSMB9/CD44/FYN/HERPUD1/FAS/ARL6IP5/KLF4/PSMA3/MTCH1/FADD/PI3/THBS1/ANXA8/CRIM1/CRYAB/MBP/FNIP1/PMAIP1/F2R/CAST/MMP9/ROBO1/SIRT1/MIR19B2/TRAF2/NKX3-1/COL6A3/TP63/TIMP4/GSN/TNF/SPINK6/SOX7/USP14/ITIH1/TNFRSF10B/SERPINH1/SERPINB1/BIRC6/MAGEA3/SPINK1/WFDC3/SERPINE1/ROCK2/BCL10/HMSD/GAS6/PPARG/SERPINA4/UBE2Z/SERPINA3/FAM162A/ATP13A2/CSTB/STAT3/SERPINA1/SERPINF2/PICALM/PSMF1/ST20	81
BP	GO:0032103	positive regulation of response to external stimulus	65/2306	323/18670	4.313e-05	0.001954	0.001503	NFKBIZ/NFKBIA/CCL5/PTGS2/IL6/TNIP1/IL1B/RIPK2/CXCL10/IL33/HSPB1/C2CD4B/CSF1/CCL7/CEBPB/FGF2/PRKCA/OSMR/C3/IDO1/IL6ST/VEGFA/DDX60/PDGFRB/GBP5/HLA-E/IL12A/CCL3L3/CMKLR1/SLIT2/ETS1/BMPR2/STX3/CCL3/SNX4/CYBA/THBS1/IL15/IL17RB/EDN1/MAPK13/DHX58/CYP27B1/PDGFD/CCL1/ITGA2/LPAR1/ABCC1/AKIRIN1/OPTN/WNT5A/HAVCR2/TNF/PGF/TLR3/CEBPA/SERPINE1/GAS6/VAMP7/NPPA/FGF10/TICAM1/MGST2/SERPINF2/ADAM8	65
BP	GO:0002758	innate immune response-activating signal transduction	61/2306	298/18670	4.361e-05	0.001954	0.001503	NFKBIA/BIRC3/TNFAIP3/IRAK2/TNIP1/PSME2/RELB/RIPK2/NFKB1/PSMA6/PSMB10/IRF1/IFIH1/BIRC2/PSMB8/RSAD2/PSMB7/PSME1/TNIP3/DDX60/IRAK4/IRF7/PAK1/CTSS/TRAF3/PSMB9/TSPAN6/IRAK3/FYN/TIFA/DDX58/PSMA3/FADD/CYBA/ITCH/CYLD/MAP3K1/DHX58/DMBT1/RAB11FIP2/FLOT1/PSMA1/PSMB2/WDFY1/PSMB3/HAVCR2/APPL2/TLR3/PRKCD/PSMA8/RTN4/LGR4/BCL10/UBB/MUC15/MUC17/PSME4/PJA2/TICAM1/PSMB5/PSMF1	61
BP	GO:0033627	cell adhesion mediated by integrin	21/2306	68/18670	4.395e-05	0.001954	0.001503	ICAM1/CCL5/LPXN/PLAU/ITGB5/ITGA4/ADA/PODXL/TGFB2/ITGB8/ITGA2/SNAI2/ITGA11/FBN1/COL16A1/SERPINE1/PDE3B/PTPN11/FERMT1/ITGBL1/CRKL	21
BP	GO:0071230	cellular response to amino acid stimulus	21/2306	68/18670	4.395e-05	0.001954	0.001503	CEBPB/SIX1/SESN1/SOCS1/COL1A1/FYN/CYBA/COL5A2/SH3BP4/PDGFD/SESN3/UBR1/BCL2L1/SESN2/TNF/ASS1/PDGFC/COL16A1/COL4A1/COL1A2/CAPN2	21
BP	GO:0019395	fatty acid oxidation	27/2306	99/18670	4.639e-05	0.002048	0.001575	PPARGC1A/ACOX2/ACACB/FABP3/HIBCH/IRS1/CROT/ACAT1/HADH/ACAT2/CPT1A/AMACR/ADIPOR2/CYGB/ABCD1/SESN2/ACAA2/DECR2/APPL2/LONP2/BDH2/ACOT8/PECR/SCP2/PPARG/ACOXL/ACADM	27
BP	GO:0031669	cellular response to nutrient levels	51/2306	237/18670	4.682e-05	0.002052	0.001579	ZC3H12A/ICAM1/NAMPT/PTGS2/XPR1/FOXO1/SESN1/GABARAPL1/SLC2A1/SLC38A2/TBL2/COL1A1/FYN/P2RY11/BMPR2/FAS/SSH1/WIPI1/CYBA/IL15/PIM1/EIF2AK4/SRD5A1/CYP27B1/INHBB/FNIP1/PMAIP1/SNAI2/SESN3/DNAJC15/VDR/SIRT1/ATG7/KCNB1/SESN2/TNC/P2RX3/BGLAP/PPM1D/MIR125B1/ASNS/KPTN/WDR45/PDXP/GAS6/MAX/PPARG/CDKN1A/SIK1/P2RX7/MYBBP1A	51
BP	GO:0032970	regulation of actin filament-based process	75/2306	388/18670	4.817e-05	0.002097	0.001613	ICAM1/FSCN1/ASAP3/ARPC1A/PDPN/DBN1/ROCK1/ARHGEF10/CNN2/PAK1/JAM3/PDGFRB/PPFIA1/CDC42EP1/ARHGAP18/LIMA1/ACTR3/CDC42EP3/SLIT2/RHOJ/PDE4D/CAMK2D/MYADM/ARHGAP28/CCDC88A/FMN2/EDN1/RDX/PXN/DSTN/DIXDC1/RHOB/PLEKHH2/LPAR1/RHOBTB3/FHOD1/RHOU/HCN4/MEF2C/PHLDB2/ARPC2/CDK5/RGS4/ADORA1/CAPZA2/ARF6/ARF1/PFN2/ARHGEF5/EPS8/GSN/SH3PXD2B/TACSTD2/ATP2A2/MIR1-2/PRKCD/SDC4/GMFB/ABL1/ROCK2/MIR214/PDE4B/PDXP/ARHGDIB/EPHA1/ACTR2/TMOD2/CDC42/MYH9/SRI/SERPINF2/TAOK1/PLEKHG2/MAGEL2/WASF2	75
BP	GO:0060993	kidney morphogenesis	26/2306	94/18670	4.901e-05	0.002118	0.00163	BMP2/LIF/AHI1/BASP1/FGF2/SIX1/STAT1/KLHL3/VEGFA/LZTS2/BMP4/PDGFRB/WWTR1/IRX3/PKD2/HOXA11/SIX4/HES5/PGF/TACSTD2/GCNT1/GATA3/HOXB7/LGR4/FGF10/OSR1	26
BP	GO:0035690	cellular response to drug	72/2306	369/18670	4.948e-05	0.002124	0.001634	ZC3H12A/ICAM1/TNFAIP3/PTGS2/IL6/GPR37L1/IL1B/MT2A/RIPK2/NFKB1/MMP3/PPARGC1A/CCL7/DAXX/FOXO1/AHR/CFLAR/KLF2/MYB/PPIF/FYN/P2RY11/SLIT2/PPP1R12A/ETS1/KLF4/NET1/SSH1/CYBA/EDN1/MAPK13/SRD5A1/PDGFD/SIRPA/ADCY7/RHOB/PPP1R9B/TP53INP1/SMYD3/ERRFI1/LDOC1/GJB2/ADCY3/STAT6/AXL/ITPR2/MEF2C/SIRT1/TRAF2/ABCC2/ATG7/NKX3-1/MTR/TXN/P2RX3/ACTB/TNF/SLAMF8/ASS1/RNF149/TLR3/PRKCD/CHMP5/PPP3CA/ABL1/ROCK2/PDE4B/PDXP/GAS6/SIGMAR1/P2RX7/CRKL	72
BP	GO:0046427	positive regulation of JAK-STAT cascade	25/2306	89/18670	5.139e-05	0.00219	0.001685	AKR1B1/CCL5/IL6/CSF2/LIF/PARP14/KIT/IL6ST/IL12A/SOCS1/SOCS3/CD40/FYN/IL26/IL15/GHR/F2R/CLCF1/PARP9/MIR19B2/HES5/TNF/IGF1/STAT3/ARL2BP	25
BP	GO:0001763	morphogenesis of a branching structure	44/2306	196/18670	5.316e-05	0.00225	0.001731	BMP2/CSF1/FGF2/SIX1/VEGFA/BMP4/PAK1/SOCS3/RDH10/RXRA/SLIT2/PKD2/HOXA11/MSX2/STK4/EDN1/SPRY1/GNA13/SNAI2/YAP1/LRP5/SIX4/VDR/WNT5A/NKX3-1/SULF1/TP63/TNC/TNF/PGF/TACSTD2/RBM15/RSPO2/PLXND1/COL4A1/HOXB7/RTN4/LGR4/PRDM1/ABL1/ENG/FGF10/SIRT6/TBX3	44
BP	GO:0030099	myeloid cell differentiation	79/2306	416/18670	5.759e-05	0.002421	0.001863	NFKBIA/MT1G/CSF2/RELB/SLC11A2/LIF/ID2/TRIB1/CDK6/CSF1/KIT/CEBPB/ISG15/MEIS1/PIK3CD/PRKCA/MAFB/EPAS1/STAT1/VEGFA/BMP4/IRF7/KLF2/MOV10/ETS1/NFE2L1/CCL3/ADAR/FADD/THBS1/ZFP36/IL15/UBASH3B/PRMT1/HIPK2/ERCC2/KAT2B/KLF13/MITF/TMEM64/THRA/BATF3/PURB/MMP9/ACIN1/MEF2C/FLI1/SIRT1/JUNB/CDKN1C/FBN1/TNF/BGLAP/RBM15/MIR125B1/HOXA9/TFE3/UBD/RBBP5/TLR3/CEBPA/GATA3/HOXB7/PPARG/PTPN11/PIP4K2A/DHRS7B/CDC42/TSPAN2/MYH9/OSTM1/STAT3/PIAS3/ARID4A/ZNF675/NCOA6/WASF2/CBFB/SNX10	79
BP	GO:0046394	carboxylic acid biosynthetic process	86/2306	462/18670	5.829e-05	0.002427	0.001868	PTGS2/CH25H/IL1B/PTGES/NFKB1/PPARGC1A/ACOX2/SLC2A6/KYNU/GLS/INSIG2/MTHFD2L/IDO1/PLA2G4A/OSBPL1A/ALDH1A3/HK2/GIP/PSPH/ACACB/ELOVL5/ENO2/ADPGK/UGP2/RDH10/NUP133/VCAN/SCD/ELOVL7/PGM2L1/GCH1/GLUD1/TRIB3/EDN1/CLTC/LIPG/ACACA/PRG3/SEPHS1/AMACR/PSAT1/CYP1A2/CBR4/ADIPOR2/PLOD2/HAS2/ELOVL2/ABCD1/GAMT/NDUFAB1/SIRT1/OSBPL3/RGN/HSD17B12/MTR/DECR2/HSD3B7/ABAT/ASS1/BHMT2/HAS1/ASNS/HAS3/ABHD3/PHGDH/MTAP/PRKAB2/CPS1/PGAM4/ACOT8/PECR/SUCLA2/SCP2/PTGS1/NUP35/MGST2/IGF1/STAT3/ALDOC/BCAT2/P2RX7/MID1IP1/FADS3/SIRT6/OSBPL7/ELOVL3	86
BP	GO:0014896	muscle hypertrophy	29/2306	111/18670	5.852e-05	0.002427	0.001868	PRKCA/JARID2/TNFRSF1B/FOXO1/IL6ST/ROCK1/PAK1/CAMK2D/LMNA/CYBA/LMCD1/EDN1/RGS2/GATA6/ERRFI1/MEF2C/MIR19B2/RGS4/PDLIM5/ATP2A2/MIR1-2/PPP3CA/ROCK2/MIR214/MYH6/NPPA/PDE5A/MIR199A2/IGF1	29
BP	GO:0061326	renal tubule development	26/2306	95/18670	5.964e-05	0.002449	0.001884	BMP2/LIF/AHI1/FGF2/SIX1/STAT1/KLHL3/VEGFA/LZTS2/BMP4/WWTR1/IRX3/PKD2/HOXA11/ACAT1/YAP1/SIX4/MEF2C/HES5/PGF/TACSTD2/GATA3/COL4A1/HOXB7/LGR4/OSR1	26
BP	GO:0070671	response to interleukin-12	17/2306	50/18670	5.984e-05	0.002449	0.001884	SOD2/PSME2/RIPK2/SERPINB2/STAT4/CNN2/IL12A/GSTO1/SIRPA/PPIA/BOLA2/ARF1/TYK2/IL12RB2/MTAP/RALA/CDC42	17
BP	GO:0097501	stress response to metal ion	9/2306	17/18670	6.299e-05	0.002516	0.001936	MT1G/MT1M/MT1E/MT1A/MT1X/MT2A/MT1H/MT1F/SLC30A1	9
BP	GO:0016053	organic acid biosynthetic process	86/2306	463/18670	6.31e-05	0.002516	0.001936	PTGS2/CH25H/IL1B/PTGES/NFKB1/PPARGC1A/ACOX2/SLC2A6/KYNU/GLS/INSIG2/MTHFD2L/IDO1/PLA2G4A/OSBPL1A/ALDH1A3/HK2/GIP/PSPH/ACACB/ELOVL5/ENO2/ADPGK/UGP2/RDH10/NUP133/VCAN/SCD/ELOVL7/PGM2L1/GCH1/GLUD1/TRIB3/EDN1/CLTC/LIPG/ACACA/PRG3/SEPHS1/AMACR/PSAT1/CYP1A2/CBR4/ADIPOR2/PLOD2/HAS2/ELOVL2/ABCD1/GAMT/NDUFAB1/SIRT1/OSBPL3/RGN/HSD17B12/MTR/DECR2/HSD3B7/ABAT/ASS1/BHMT2/HAS1/ASNS/HAS3/ABHD3/PHGDH/MTAP/PRKAB2/CPS1/PGAM4/ACOT8/PECR/SUCLA2/SCP2/PTGS1/NUP35/MGST2/IGF1/STAT3/ALDOC/BCAT2/P2RX7/MID1IP1/FADS3/SIRT6/OSBPL7/ELOVL3	86
BP	GO:0003300	cardiac muscle hypertrophy	28/2306	106/18670	6.311e-05	0.002516	0.001936	PRKCA/JARID2/TNFRSF1B/FOXO1/IL6ST/ROCK1/PAK1/CAMK2D/LMNA/LMCD1/EDN1/RGS2/GATA6/ERRFI1/MEF2C/MIR19B2/RGS4/PDLIM5/ATP2A2/MIR1-2/PPP3CA/ROCK2/MIR214/MYH6/NPPA/PDE5A/MIR199A2/IGF1	28
BP	GO:0042136	neurotransmitter biosynthetic process	28/2306	106/18670	6.311e-05	0.002516	0.001936	ZC3H12A/ICAM1/PTGS2/IL1B/SLC7A2/DDAH1/SLC22A2/KLF2/PKD2/KLF4/GCH1/GLA/EDN1/SIRPA/PRG3/MOXD1/DAGLA/RGN/ABAT/TNF/ASS1/DAGLB/DDAH2/PTX3/ROCK2/HBB/TICAM1/MIR199A2	28
BP	GO:0034440	lipid oxidation	27/2306	101/18670	6.774e-05	0.00268	0.002062	PPARGC1A/ACOX2/ACACB/FABP3/HIBCH/IRS1/CROT/ACAT1/HADH/ACAT2/CPT1A/AMACR/ADIPOR2/CYGB/ABCD1/SESN2/ACAA2/DECR2/APPL2/LONP2/BDH2/ACOT8/PECR/SCP2/PPARG/ACOXL/ACADM	27
BP	GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism	48/2306	222/18670	6.808e-05	0.00268	0.002062	CXCL6/ZC3H12A/CCL5/TNIP1/MX1/ISG20/CCL8/OAS1/ISG15/FBXL2/OAS3/IFITM1/RSAD2/PLSCR1/STAT1/IFIT1/APOBEC3G/TRIM25/CHMP4B/CCL3/ADAR/ZFP36/OASL/EIF2AK4/APOBEC3H/PPIA/PDE12/IGF2R/PABPC1/TRIM21/FAM111A/RAD23A/GSN/DDX5/TNF/STAU1/TRIM6/PTX3/ADARB1/APOBEC3F/ZNF639/NUCKS1/KPNA2/BTBD17/PKN2/TRIM38/GTF2F2/SNX3	48
BP	GO:0009612	response to mechanical stimulus	46/2306	210/18670	6.868e-05	0.002686	0.002067	NFKBIA/BDKRB1/PTGS2/IL1B/CXCL10/NFKB1/IRF1/KIT/SLC2A1/STAT1/SLC38A2/PSPH/CNN2/COL1A1/CD40/FYN/ETS1/FAS/PKD2/BACE1/FADD/CYBA/THBS1/MAP3K1/EDN1/ITGA2/GDF5/LRP11/JUNB/BTG2/TNC/P2RX3/MAP3K2/BGLAP/ETV1/TNFRSF10B/ASNS/ATP8A2/TLR3/USP53/BCL10/PPARG/PTPN11/ENG/NPPA/P2RX7	46
BP	GO:0010611	regulation of cardiac muscle hypertrophy	22/2306	75/18670	6.989e-05	0.002716	0.00209	PRKCA/JARID2/TNFRSF1B/FOXO1/IL6ST/ROCK1/PAK1/CAMK2D/LMNA/LMCD1/EDN1/RGS2/ERRFI1/MIR19B2/RGS4/MIR1-2/PPP3CA/ROCK2/MIR214/PDE5A/MIR199A2/IGF1	22
BP	GO:0001701	in utero embryonic development	72/2306	373/18670	7.075e-05	0.002733	0.002102	BMP2/MAFF/CSF2/LIF/PLCD3/PPP4R4/MBNL1/ARNT2/CEBPB/PLCD1/EPAS1/DBN1/APBA3/VEGFA/PSPH/KLF2/TM4SF1/SOCS3/RDH10/RXRA/NR2F2/PKD2/MAFG/KIDINS220/ADA/STK4/EDN1/PRMT1/TET1/MYO1E/PHLDA2/STMN3/ERCC2/AKAP3/GATA6/GNA13/ADCY9/GNA12/ASCL2/POLB/JUNB/BCL2L1/CDKN1C/SLC30A1/HES3/MGAT1/SSR2/SLC25A20/ELF3/BIRC6/CEBPA/KRT19/GATA3/INPP5B/ZNF830/EIF2S2/RTN4/PRDM1/DAD1/ELL/ANKRD11/MYH6/POLG2/MYH9/MIB1/IGF1/MYH10/TBL1XR1/BPTF/CAPN2/NPM2/TBX3	72
BP	GO:0060562	epithelial tube morphogenesis	64/2306	322/18670	7.226e-05	0.002758	0.002122	BMP2/CXCL10/CSF1/AHI1/NTN1/FGF2/SIX1/KLHL3/VEGFA/LZTS2/BMP4/PAK1/FZD1/RDH10/SLIT2/IRX3/PKD2/SHROOM3/HOXA11/MSX2/STK4/EDN1/FZD2/PODXL/RHOB/TGFB2/SPRY1/GNA13/YAP1/STARD13/LRP5/SETDB2/CEP290/SIX4/MEF2C/VDR/WNT5A/NKX3-1/HES5/TNC/PTK7/TNF/PGF/TACSTD2/RBM15/RSPO2/PLXND1/GATA3/COL4A1/HOXB7/ARID1A/SDC4/LGR4/ABL1/BCL10/RALA/ENG/FGF10/MIB1/DVL1/OSR1/DVL2/SIRT6/TBX3	64
BP	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	26/2306	96/18670	7.23e-05	0.002758	0.002122	PSME2/TAP1/TAP2/PSMA6/PSMB10/PSMB8/PSMB7/PSME1/HLA-E/PSMB9/HLA-F/ITGB5/PSMA3/CYBA/HLA-A/PSMA1/PSMB2/PSMB3/PSMA8/HLA-G/TAPBP/PSME4/PSMB5/HLA-B/HLA-H/PSMF1	26
BP	GO:0010921	regulation of phosphatase activity	40/2306	175/18670	7.484e-05	0.002826	0.002174	BMP2/ITGA1/ENSA/PPP4R4/PPP1R15A/ROCK1/PPP2R1B/PDGFRB/SET/CALM1/PPP1R12A/SLC39A10/DMPK/SEMA4D/PPP1R9B/TGFB2/ITGA2/PHACTR2/CCDC8/NUAK1/RCAN1/MEF2C/RGN/TNF/PPP2R5E/CALM2/FKBP1A/TMEM225/ANKLE2/ROCK2/PPP2R5C/ELL/PPP1R14C/PPP1R7/FARP1/SH3RF2/RCAN2/SHOC2/MYO1D/CHP2	40
BP	GO:0052547	regulation of peptidase activity	84/2306	452/18670	7.499e-05	0.002826	0.002174	BIRC3/BID/PTGS2/PSME2/SERPINA9/RIPK2/SERPINB2/SH3RF1/ADORA2A/SERPINB8/RECK/BIRC2/PSMB8/PRR7/PSME1/C3/DAPK1/TNFAIP8/PDCD5/VEGFA/CFLAR/PSMB9/CD44/FYN/HERPUD1/FAS/ARL6IP5/KLF4/PSMA3/MTCH1/FADD/PI3/THBS1/ANXA8/CRIM1/CRYAB/MBP/FNIP1/PMAIP1/F2R/CAST/MMP9/ROBO1/SIRT1/MIR19B2/TRAF2/RCN3/NKX3-1/COL6A3/TP63/TIMP4/GSN/UBXN1/TNF/SPINK6/SOX7/USP14/ITIH1/TNFRSF10B/SERPINH1/SERPINB1/BIRC6/MAGEA3/SPINK1/WFDC3/SERPINE1/ROCK2/BCL10/HMSD/GAS6/PPARG/SERPINA4/PSME4/UBE2Z/SERPINA3/FAM162A/ATP13A2/CSTB/STAT3/SERPINA1/SERPINF2/PICALM/PSMF1/ST20	84
BP	GO:0050708	regulation of protein secretion	87/2306	472/18670	7.606e-05	0.002849	0.002192	ZC3H12A/TNFAIP3/CCL5/IL6/IL1B/RIPK2/IL33/KCNN4/ENSA/ADORA2A/IL1A/IFIH1/IFNGR1/PRKCA/TNFRSF14/RSAD2/TNFRSF1B/SLC2A1/PANX1/GIP/HLA-E/IL4R/SOCS1/CD58/CD40/LRRC32/IRS1/DDX58/IL26/PANX2/CCL3/GBP1/IL17RB/GLUD1/RHBDF2/HADH/AKAP12/GSDMD/TCF7L2/MBP/INHBB/MYOM1/ARNTL/F2R/CPT1A/CCL1/TGFB2/SERGEF/PPIA/LRP5/ITPR2/SRGN/WNT5A/TRAF2/KCNB1/VPS35/ANXA4/MYO18A/ARF6/SYT4/ARF1/ABAT/HAVCR2/TNF/SYTL4/DYNLL1/BRSK2/SERPINB1/TRIM6/GATA3/PPP3CA/LGR4/ABL1/RAB11FIP1/GAS6/PTPN11/PYDC2/FERMT1/ATP13A2/IGF1/MYH10/ARL2BP/SRI/P2RX7/MAPKBP1/ADAM8/ADRA2A	87
BP	GO:0051348	negative regulation of transferase activity	58/2306	285/18670	7.862e-05	0.00291	0.002239	TNFAIP3/IL1B/TRIB1/ADORA2A/HSPB1/TRIB2/BAG2/EIF4A2/GPRC5A/DUSP6/CORO1C/DNAJA1/BMP4/WWTR1/SOCS1/SOCS3/COX11/DUSP14/IRAK3/NR2F2/LATS2/ADAR/ZFP36/UBASH3B/TRIB3/KAT2B/RGS2/DNAJC3/SPRY1/SMYD3/ERRFI1/HEXIM2/DUSP3/POT1/LRP5/CDKN2C/SIRT1/RGS4/RGN/CDKN1C/CEBPA/DUSP16/PRKCD/ADARB1/ITPRIP/GMFB/ABL1/DUSP18/DUSP10/PKIG/PPARG/CDKN1A/EPHA1/DUSP5/CBLB/MIR218-1/DVL1/ZNF675	58
BP	GO:0031667	response to nutrient levels	91/2306	499/18670	7.863e-05	0.00291	0.002239	ZC3H12A/ICAM1/NAMPT/PTGS2/VCAM1/IL1B/CXCL10/ENSA/ABCA1/PPARGC1A/XPR1/KYNU/FOXO1/SESN1/GABARAPL1/SLC2A1/STAT1/PANX1/GIP/SLC38A2/PSPH/ACACB/TBL2/COL1A1/TRIM25/FYN/BCKDHB/P2RY11/BMPR2/FAS/CCND1/SSH1/WIPI1/SGIP1/CYBA/ZFP36/IL15/PIM1/ADA/ACAT1/EIF2AK4/SRD5A1/CYP27B1/INHBB/FNIP1/PMAIP1/LIPG/ITGA2/SNAI2/SESN3/BBS2/ADIPOR2/DNAJC15/TMEM135/LRP11/VDR/SIRT1/ATG7/KCNB1/GDF15/SESN2/TNC/GSN/P2RX3/BGLAP/PPM1D/ASS1/APPL2/SPARC/MIR125B1/ASNS/CPS1/KPTN/WDR45/BCL10/SLC22A3/PDXP/GAS6/DAD1/MAX/PPARG/CDKN1A/SIK1/TNFRSF11B/NMUR2/P2RX7/TBL1XR1/MYBBP1A/FOXO4/SIRT6/RMI1	91
BP	GO:0051346	negative regulation of hydrolase activity	86/2306	466/18670	7.979e-05	0.002935	0.002258	BIRC3/PTGS2/SERPINA9/ENSA/SERPINB2/SH3RF1/ADORA2A/SERPINB8/PPP4R4/RECK/BIRC2/C3/TNFAIP8/VEGFA/PPP1R15A/ROCK1/CFLAR/IFIT1/SET/PPIF/CD44/FICD/SLIT2/HERPUD1/SORT1/KLF4/PI3/THBS1/ANXA8/CRIM1/EGLN1/CRYAB/RDX/FNIP1/SH3BP4/THADA/SEMA4D/PPP1R9B/TGFB2/CAST/RGS2/SPRY1/PHACTR2/CCDC8/MMP9/CNN3/SIRT1/MIR19B2/COL6A3/RGN/TIMP4/DGKI/UBXN1/TNF/SPINK6/USP14/ITIH1/PXK/SERPINH1/SERPINB1/FKBP1A/BIRC6/TMEM225/MAGEA3/SPINK1/WFDC3/PTX3/SERPINE1/ABL1/ROCK2/HMSD/GAS6/ELL/PPP1R14C/FARP1/SERPINA4/MNAT1/UBE2Z/SH3RF2/SERPINA3/CSTB/MYO1D/SERPINA1/SERPINF2/PICALM/PSMF1	86
BP	GO:0051547	regulation of keratinocyte migration	8/2306	14/18670	8.05e-05	0.002944	0.002265	IQSEC1/EPB41L4B/HBEGF/HAS2/MMP9/ARF6/MAPRE2/FGF10	8
BP	GO:0001738	morphogenesis of a polarized epithelium	34/2306	141/18670	8.294e-05	0.003015	0.00232	PSME2/PSMA6/PSMB10/AHI1/DAB2/PSMB8/PSMB7/PSME1/ANKRD6/PSMB9/FZD1/GPC4/PSMA3/ROR1/FZD2/CLTC/PSMA1/PSMB2/WNT5A/TP63/PSMB3/PTK7/BRSK2/FZD4/PSMA8/ABL1/PSME4/CDC42/PSMB5/DVL1/DVL2/FZD7/PLEKHA4/PSMF1	34
BP	GO:0071280	cellular response to copper ion	12/2306	29/18670	8.342e-05	0.003015	0.00232	MT1G/MT1M/MT1E/MT1A/MT1X/MT2A/MT1H/MT1F/DAXX/NFE2L1/BACE1/CYP1A2	12
BP	GO:0090183	regulation of kidney development	18/2306	56/18670	8.489e-05	0.00305	0.002347	LIF/BASP1/SIX1/STAT1/VEGFA/CFLAR/BMP4/PDGFRB/WWTR1/PDGFD/YAP1/MMP9/SIX4/TACSTD2/GATA3/HOXB7/LGR4/OSR1	18
BP	GO:1903039	positive regulation of leukocyte cell-cell adhesion	47/2306	218/18670	8.673e-05	0.003083	0.002372	NFKBIZ/ICAM1/CCL5/IL6/CD70/VCAM1/MAP3K8/IL1B/CD83/RIPK2/CCL2/TNFSF9/IL7R/TNFRSF14/PDCD1LG2/IL6ST/TNFSF13B/PAK1/HLA-E/IL12A/MYB/IL4R/SOCS1/CD44/FYN/ETS1/FADD/ITGA4/IL15/CYLD/ADA/SIRPA/EBI3/HAS2/EFNB1/HAVCR2/TNF/GATA3/HLA-G/BCL10/DUSP10/PTPN11/CDC42/IGF1/SASH3/ADAM8/CBFB	47
BP	GO:0051091	positive regulation of DNA-binding transcription factor activity	54/2306	261/18670	8.681e-05	0.003083	0.002372	ICAM1/IRAK2/IL6/IL1B/RIPK2/NFKB1/PSMA6/NFKB2/NDP/PPARGC1A/KIT/ARID5B/VEGFA/IRAK4/CFLAR/IL18R1/FZD1/TRIM25/CD40/IRAK3/DDX58/TRIM37/NEUROG3/EDN1/CYTL1/ROR1/FZD2/HIPK2/RPS6KA4/FLOT1/CARM1/MIR19B2/WNT5A/TRAF2/NKX3-1/TRIM21/RIPK4/ARHGEF5/TNF/FZD4/TLR3/PPP3CA/LRRFIP1/RBCK1/BCL10/UBB/PPARG/TICAM1/TRAPPC9/TRIM38/STAT3/DVL2/ADAM8/CRTC3	54
BP	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	21/2306	71/18670	8.877e-05	0.003133	0.00241	CCL5/IL6/CSF2/LIF/PARP14/KIT/IL6ST/IL12A/SOCS3/CD40/FYN/IL15/GHR/CLCF1/PARP9/MIR19B2/HES5/TNF/IGF1/STAT3/ARL2BP	21
BP	GO:0045428	regulation of nitric oxide biosynthetic process	20/2306	66/18670	8.921e-05	0.003133	0.00241	ZC3H12A/ICAM1/PTGS2/IL1B/DDAH1/KLF2/PKD2/KLF4/GLA/EDN1/SIRPA/RGN/TNF/ASS1/DDAH2/PTX3/ROCK2/HBB/TICAM1/MIR199A2	20
BP	GO:0035457	cellular response to interferon-alpha	7/2306	11/18670	9.11e-05	0.003156	0.002428	IFNAR1/IFIT3/PDE12/AXL/IFIT2/GATA3/GAS6	7
BP	GO:0070757	interleukin-35-mediated signaling pathway	7/2306	11/18670	9.11e-05	0.003156	0.002428	STAT4/STAT1/IL6ST/IL12A/EBI3/IL12RB2/STAT3	7
BP	GO:0030111	regulation of Wnt signaling pathway	70/2306	363/18670	9.141e-05	0.003156	0.002428	BMP2/TNFAIP3/PSME2/NFKB1/PSMA6/PSMB10/DAB2/RECK/PSMB8/PSMB7/PSME1/FOXO1/MCC/ANKRD6/LZTS2/NKD2/PSMB9/WWTR1/FZD1/COL1A1/LATS2/PSMA3/CYLD/SULF2/STK4/UBR5/TCF7L2/DIXDC1/ARNTL/TMEM64/CSNK1G2/SNAI2/WNT5B/YAP1/CSNK1E/DAAM2/PSMA1/PSMB2/DACT3/MIR19B2/WNT5A/VPS35/SULF1/PSMB3/SHISA2/PTK7/SOX7/MIR1-2/RSPO2/JRK/TCF7L1/PSMA8/LGR4/ABL1/FGF10/TLE1/SPIN1/PSME4/FERMT1/PSMB5/DVL1/DVL2/CSNK1G3/TBL1XR1/FZD7/SDHAF2/PLEKHA4/PSMF1/CBFB/SNX3	70
BP	GO:0006631	fatty acid metabolic process	73/2306	383/18670	9.599e-05	0.003296	0.002536	PTGS2/IL1B/PTGES/PPARGC1A/LPIN1/ACOX2/SLC27A3/C3/INSIG2/PLA2G4A/GIP/ACACB/ELOVL5/AIG1/FABP3/HIBCH/PLA2G4C/IRS1/CYP2U1/NFE2L1/SCD/ELOVL7/NUDT7/CROT/ACAT1/TRIB3/EDN1/HADH/ACSF2/ACAT2/LIPG/CPT1A/ACACA/AMACR/ACSL5/CYP1A2/CBR4/ADIPOR2/CYGB/ELOVL2/ABCD1/DAGLA/NDUFAB1/SIRT1/CRYL1/RGN/HSD17B12/SESN2/ACAA2/DECR2/APPL2/DAGLB/ABHD5/ALDH5A1/ABHD3/GPAM/PRKAB2/LONP2/BDH2/PDK3/ACOT8/PECR/SCP2/PPARG/PTGS1/ACOXL/FAAH2/ACADM/CYP2C19/MID1IP1/CYP2S1/FADS3/ELOVL3	73
BP	GO:0046209	nitric oxide metabolic process	23/2306	82/18670	0.0001036	0.003536	0.002721	ZC3H12A/ICAM1/PTGS2/IL1B/SLC7A2/DDAH1/KLF2/PKD2/KLF4/GCH1/GLA/EDN1/SIRPA/RGN/TNF/ASS1/DDAH2/PTX3/CPS1/ROCK2/HBB/TICAM1/MIR199A2	23
BP	GO:0000302	response to reactive oxygen species	49/2306	232/18670	0.0001064	0.0036	0.00277	SOD2/TNFAIP3/IL6/GPR37L1/MMP3/PPARGC1A/FOXO1/SESN1/STAT1/CFLAR/KLF2/PDGFRB/MYB/COL1A1/PPIF/FYN/ETS1/PKD2/KLF4/NET1/GCH1/ADA/EDN1/MAPK13/EGLN1/CRYAB/PXN/PDGFD/SIRPA/RHOB/SESN3/STAT6/MMP9/AXL/SIRT1/TRAF2/RGN/CAMKK2/ADPRHL2/MTR/SESN2/TXN/TNF/PRKCD/GLRX2/ABL1/HBB/SIGMAR1/CAPN2	49
BP	GO:0014897	striated muscle hypertrophy	28/2306	109/18670	0.0001072	0.0036	0.00277	PRKCA/JARID2/TNFRSF1B/FOXO1/IL6ST/ROCK1/PAK1/CAMK2D/LMNA/LMCD1/EDN1/RGS2/GATA6/ERRFI1/MEF2C/MIR19B2/RGS4/PDLIM5/ATP2A2/MIR1-2/PPP3CA/ROCK2/MIR214/MYH6/NPPA/PDE5A/MIR199A2/IGF1	28
BP	GO:0072009	nephron epithelium development	28/2306	109/18670	0.0001072	0.0036	0.00277	BMP2/LIF/AHI1/BASP1/FGF2/SIX1/STAT1/KLHL3/VEGFA/LZTS2/BMP4/WWTR1/IRX3/PKD2/HOXA11/ACAT1/MYO1E/PODXL/YAP1/SIX4/MEF2C/HES5/PGF/TACSTD2/GATA3/HOXB7/LGR4/OSR1	28
BP	GO:0006809	nitric oxide biosynthetic process	22/2306	77/18670	0.0001078	0.0036	0.00277	ZC3H12A/ICAM1/PTGS2/IL1B/SLC7A2/DDAH1/KLF2/PKD2/KLF4/GCH1/GLA/EDN1/SIRPA/RGN/TNF/ASS1/DDAH2/PTX3/ROCK2/HBB/TICAM1/MIR199A2	22
BP	GO:0033673	negative regulation of kinase activity	53/2306	257/18670	0.0001096	0.003612	0.002779	TNFAIP3/IL1B/TRIB1/ADORA2A/HSPB1/TRIB2/GPRC5A/DUSP6/CORO1C/DNAJA1/BMP4/WWTR1/SOCS1/SOCS3/COX11/DUSP14/IRAK3/NR2F2/LATS2/ADAR/UBASH3B/TRIB3/KAT2B/RGS2/DNAJC3/SPRY1/SMYD3/ERRFI1/HEXIM2/DUSP3/LRP5/CDKN2C/SIRT1/RGS4/RGN/CDKN1C/CEBPA/DUSP16/PRKCD/ADARB1/ITPRIP/GMFB/ABL1/DUSP18/DUSP10/PKIG/CDKN1A/EPHA1/DUSP5/CBLB/MIR218-1/DVL1/ZNF675	53
BP	GO:0048863	stem cell differentiation	53/2306	257/18670	0.0001096	0.003612	0.002779	PSME2/LIF/PSMA6/CDK6/PSMB10/KIT/PSMB8/JARID2/PSMB7/PSME1/FAM172A/CORO1C/BMP4/PSMB9/MYB/FZD1/TCF12/RDH10/PSMA3/ITCH/MSX2/EDN1/LBH/ZFP36L2/ZNF281/SEMA4D/SOX5/ERCC2/TGFB2/GATA6/SNAI2/YAP1/EFNB1/PSMA1/MEF2C/PSMB2/TP63/PSMB3/HES5/TACSTD2/PUS7/TRIM6/GATA3/PSMA8/ABL1/PSME4/PSMB5/SEMA4F/STAT3/OSR1/FOXO4/PSMF1/CBFB	53
BP	GO:0071398	cellular response to fatty acid	18/2306	57/18670	0.0001099	0.003612	0.002779	ZC3H12A/PID1/CLDN1/PPARGC1A/PTGFR/IRS1/EDN1/PTGER2/CPT1A/ACACA/AKAP8/TNC/ASS1/CPS1/PDK3/PPARG/ID3/GNG2	18
BP	GO:0016042	lipid catabolic process	65/2306	333/18670	0.0001111	0.003632	0.002795	IL1B/PLD1/PLCD3/LPIN1/ACOX2/PLCE1/PLCD1/PLA2G4A/ACACB/LIPA/AIG1/FABP3/HIBCH/PLA2G4C/IRS1/IDH1/NUDT7/CROT/NAGA/GLA/ACAT1/HADH/SRD5A1/CYP27B1/IAH1/PPT1/ACAT2/LIPG/CPT1A/AMACR/CYP1A2/THRA/ABCD1/PLCB4/DAGLA/PLA2G12A/ADORA1/SESN2/ACAA2/DECR2/PAFAH1B2/HSD3B7/TNF/YWHAH/DAGLB/ABHD5/ABHD3/PRKCD/LONP2/CPS1/BDH2/HSD17B6/ACOT8/PECR/PDE3B/SCP2/MGST2/PNLIPRP3/ACOXL/TBL1XR1/ACADM/CYP19A1/ADRA2A/CRTC3/PLD3	65
BP	GO:1905276	regulation of epithelial tube formation	9/2306	18/18670	0.0001122	0.003643	0.002803	SIX1/FZD1/FZD2/SIX4/WNT5A/PTK7/GATA3/DVL1/DVL2	9
BP	GO:0072080	nephron tubule development	25/2306	93/18670	0.0001126	0.003643	0.002803	BMP2/LIF/AHI1/FGF2/SIX1/STAT1/KLHL3/VEGFA/LZTS2/BMP4/WWTR1/IRX3/PKD2/HOXA11/ACAT1/YAP1/SIX4/MEF2C/HES5/PGF/TACSTD2/GATA3/HOXB7/LGR4/OSR1	25
BP	GO:0046677	response to antibiotic	64/2306	327/18670	0.0001153	0.003703	0.002849	ZC3H12A/ICAM1/TNFAIP3/IL6/VCAM1/GPR37L1/CLDN1/CCL7/BIRC2/DAXX/FOXO1/AHR/STAT1/PLA2G4A/KLF2/PDGFRB/MYB/COL1A1/PPIF/FYN/ETS1/CCND1/KLF4/NET1/ADA/ACTC1/EDN1/MAPK13/SRD5A1/CRYAB/PDGFD/SIRPA/ADCY7/RHOB/TP53INP1/RGS2/GJB2/ADCY3/STAT6/POLB/AXL/ITPR2/MEF2C/SIRT1/RGS4/BCL2L1/TXN/TNC/EPS8/GSN/ABAT/BGLAP/SPARC/GATA3/PRKCD/GLRX2/GRIN3A/ABL1/HBB/ACTR2/SIGMAR1/ID3/STAT3/CAPN2	64
BP	GO:0007548	sex differentiation	55/2306	270/18670	0.0001156	0.003703	0.002849	ICAM1/CITED2/KIT/CEBPB/BASP1/ARID5B/VEGFA/EREG/RAB13/PDGFRB/AFP/IRX5/DNAJC19/BCL2L2/RDH10/SLIT2/CCND1/IDH1/HOXA11/LHX8/HOXA10/SRD5A1/INHBB/LHFPL2/TGFB2/GATA6/NUDT1/RHOBTB3/ASB1/SIX4/AXL/SIRT1/WNT5A/NKX3-1/BCL2L1/TP63/MAMLD1/FZD4/EIF2B5/HOXA9/EIF2B4/TLR3/PTX3/GATA3/ZNF830/EIF2S2/LGR4/UBB/PTPN11/FGF10/OSR1/CYP19A1/CRKL/ARID4A/TBX3	55
BP	GO:0014812	muscle cell migration	27/2306	104/18670	0.0001164	0.003709	0.002854	CCL5/TRIB1/PPARGC1A/SIX1/ROCK1/PAK1/PDGFRB/PLAU/SLIT2/NET1/SSH1/PDGFD/ITGA2/LPAR1/HAS2/PLEKHO1/SIX4/MEF2C/AKIRIN1/MIR137/BIN3/DOCK4/SERPINE1/MIR214/IGF1/MIR218-1/FOXO4	27
BP	GO:0006470	protein dephosphorylation	63/2306	321/18670	0.0001196	0.003791	0.002917	PPP3CC/ITGA1/ENSA/PPP4R4/PTPRE/DUSP6/PPP1R15A/ROCK1/PPP2R1B/PDGFRB/SET/DUSP14/CALM1/PPP1R12A/CDC25A/SSH1/SLC39A10/UBASH3B/PTPN13/DUSP23/DMPK/CDC14B/PPP1R9B/PHACTR2/PPP4C/NUAK1/RCAN1/DUSP3/ADORA1/UBLCP1/RGN/TNF/CAMK2G/PPM1D/PPP2R5E/CALM2/PPM1M/PTPRM/FKBP1A/DUSP12/DUSP16/PRKCD/ANKLE2/PPP3CA/DUSP18/CTDSPL2/ROCK2/PPP2R5C/DUSP10/PDXP/CTDSP2/PPP1R14C/PPP1R7/PTPN11/MYH6/DUSP5/SH3RF2/RCAN2/SHOC2/LRRC30/SBF1/EYA2/SDHAF2	63
BP	GO:0044282	small molecule catabolic process	82/2306	445/18670	0.0001219	0.003843	0.002956	CBR3/GK/LPIN1/ENTPD7/FGF2/DDAH1/ACOX2/KYNU/GLS/IDO1/TYMP/HK2/ACACB/GALM/ENO2/APOBEC3G/ADPGK/AIG1/CD44/NAGK/PNKD/HIBCH/BCKDHB/IRS1/IL4I1/PGM2L1/NUDT18/NUDT7/CROT/FAH/ADA/ACAT1/GLUD1/HADH/CYP27B1/PCYOX1/GLB1/APOBEC3H/ACAT2/HNMT/CPT1A/ADH5/IMPA2/AMACR/NUDT1/AADAT/LRP5/ABCD1/SULT1C4/HAGH/HIBADH/CRYL1/AMT/ALDH7A1/SESN2/ACAA2/DECR2/ESD/CDADC1/HSD3B7/ABAT/MGAT1/ADO/DDAH2/ALDH5A1/ABHD3/INPP5B/LONP2/BDH2/APOBEC3F/LDHD/ACOT8/ENOSF1/PECR/PDXP/SCP2/INPP1/ALDH1L2/ACOXL/ALDOC/BCAT2/ACADM	82
BP	GO:1903532	positive regulation of secretion by cell	75/2306	399/18670	0.0001228	0.003853	0.002964	IL6/IL1B/RIPK2/IL33/KCNN4/ADORA2A/IL1A/IFIH1/IFNGR1/C1QTNF1/TNFRSF14/RAB9A/PANX1/GIP/HLA-E/MYB/IL4R/HLA-F/CD58/DDX58/IL26/PANX2/CCL3/SNX4/OXTR/IL17RB/GLUD1/EDN1/RAB2B/AKAP12/GSDMD/TCF7L2/RAB3GAP1/MBP/INHBB/MYOM1/SDCBP/F2R/CCL1/TGFB2/PPIA/CDK5/WNT5A/KCNB1/NKX3-1/VPS35/MYO18A/RAB3A/ARF6/SYT4/ARF1/ABAT/HAVCR2/TNF/SYTL4/DYNLL1/STXBP5/STXBP1/TRIM6/GATA3/SYT1/SDC4/ABL1/VAMP7/PTPN11/NPPA/FERMT1/ATP13A2/IGF1/MYH10/SRI/P2RX7/ADAM8/PDCD6IP/CYP19A1	75
BP	GO:0001818	negative regulation of cytokine production	59/2306	296/18670	0.000125	0.003885	0.002989	ZC3H12A/TNFAIP3/IL6/RELB/CD83/IL33/NFKB1/TRIB2/IFIH1/UBE2L6/ISG15/PDCD1LG2/IDO1/KLF2/IL12A/CMKLR1/TRIM25/HLA-F/IRAK3/LRRC32/DDX58/KLF4/GBP1/ITCH/THBS1/ZFP36/UBA7/CYLD/DHX58/INHBB/SIRPA/MC1R/ADCY7/TGFB2/GATA6/ERRFI1/RPS6KA4/ASB1/ABCD1/BCL3/AXL/SRGN/ANXA4/AKAP8/HAVCR2/TNF/APPL2/HERC5/MIR125B1/SERPINB1/GATA3/NPTN/LGR4/TAX1BP1/GAS6/PYDC2/IGF1/MAPKBP1/HOMER2	59
BP	GO:0001659	temperature homeostasis	39/2306	173/18670	0.0001251	0.003885	0.002989	PTGS2/IL1B/DIO2/IL1A/PPARGC1A/LPIN1/CEBPB/NPR3/EPAS1/FOXO1/G0S2/VEGFA/IL18R1/IL4R/CMKLR1/FTO/SCD/IL15/OXTR/HADH/ARNTL/THRA/FH/ADIPOR2/STAT6/GADD45G/ARRDC3/ADORA1/ABAT/TNF/APPL2/TFE3/PDGFC/ADRB3/PRKAB2/LGR4/STAT3/SIRT6/ELOVL3	39
BP	GO:0002711	positive regulation of T cell mediated immunity	16/2306	48/18670	0.0001281	0.003959	0.003046	IL6/IL1B/RSAD2/HLA-E/IL12A/IL18R1/HLA-F/FADD/HLA-A/TRAF2/GATA3/HLA-G/P2RX7/HLA-B/SASH3/HLA-H	16
BP	GO:0071453	cellular response to oxygen levels	49/2306	234/18670	0.0001327	0.004029	0.0031	ICAM1/NAMPT/PTGS2/PSME2/PSMA6/PSMB10/PPARGC1A/CITED2/DDAH1/PSMB8/PSMB7/PSME1/EPAS1/FOXO1/VEGFA/EEF2K/CFLAR/TBL2/PSMB9/FAS/PSMA3/LMNA/FMN2/EDN1/EGLN1/PMAIP1/HIPK2/LPAR1/GATA6/PSMA1/PSMB2/SIRT1/ATG7/NKX3-1/PSMB3/ACAA2/HYOU1/PSMA8/PDK3/ROCK2/MIR214/UBB/PPARG/PSME4/FAM162A/PSMB5/CLCA1/ADAM8/PSMF1	49
BP	GO:0014743	regulation of muscle hypertrophy	22/2306	78/18670	0.0001328	0.004029	0.0031	PRKCA/JARID2/TNFRSF1B/FOXO1/IL6ST/ROCK1/PAK1/CAMK2D/LMNA/LMCD1/EDN1/RGS2/ERRFI1/MIR19B2/RGS4/MIR1-2/PPP3CA/ROCK2/MIR214/PDE5A/MIR199A2/IGF1	22
BP	GO:0072028	nephron morphogenesis	22/2306	78/18670	0.0001328	0.004029	0.0031	BMP2/LIF/AHI1/FGF2/SIX1/STAT1/KLHL3/VEGFA/LZTS2/BMP4/PDGFRB/IRX3/PKD2/HOXA11/SIX4/HES5/PGF/TACSTD2/GATA3/HOXB7/LGR4/OSR1	22
BP	GO:0008360	regulation of cell shape	35/2306	150/18670	0.000133	0.004029	0.0031	ICAM1/CCL2/CCL7/KIT/PDPN/VEGFA/CDC42EP1/ARHGAP18/FYN/CDC42EP3/RHOJ/CCL3/MKLN1/SHROOM3/RDX/SEMA4D/EPB41L3/RHOB/FMNL2/FGD4/LPAR1/GNA13/RHOBTB3/FGD1/GNA12/RHOU/PLEKHO1/EPS8/FERMT2/PLXND1/DIAPH1/MYO10/CDC42/MYH9/MYH10	35
BP	GO:0030856	regulation of epithelial cell differentiation	36/2306	156/18670	0.0001363	0.004095	0.003151	MAFF/IL1B/LIF/S1PR3/AHI1/CEBPB/STAT1/VEGFA/ROCK1/BMP4/WWTR1/CCND1/MAFG/ZFP36/MSX2/CYP27B1/ARNTL/ERRFI1/YAP1/MMP9/VDR/MIR18B/TP63/HES5/FOXJ2/CDKN1C/TNF/MIR1-2/GATA3/SERPINE1/ROCK2/OSR1/ATOH8/SULT2B1/TBX3/CBFB	36
BP	GO:0032964	collagen biosynthetic process	17/2306	53/18670	0.0001365	0.004095	0.003151	IL6/TRAM2/BMP4/PDGFRB/MYB/COL1A1/F2R/ITGA2/ERRFI1/CYGB/RCN3/SERPINH1/PPARG/ENG/MIR218-1/SERPINF2/COL5A1	17
BP	GO:1903037	regulation of leukocyte cell-cell adhesion	60/2306	304/18670	0.0001462	0.004363	0.003357	NFKBIZ/ZC3H12A/ICAM1/CCL5/IL6/CD70/VCAM1/MAP3K8/IL1B/CD83/RIPK2/CCL2/ADORA2A/IRF1/TNFSF9/CEBPB/IL7R/TNFRSF14/PDCD1LG2/IDO1/IL6ST/BMP4/TNFSF13B/PAK1/HLA-E/IL12A/MYB/IL4R/SOCS1/CD44/FYN/ETS1/LRRC32/KLF4/FADD/ITGA4/IL15/CYLD/ADA/MAD1L1/SIRPA/EBI3/HAS2/DUSP3/EFNB1/HAVCR2/TNF/ASS1/GATA3/HLA-G/SDC4/BCL10/DUSP10/PTPN11/CDC42/PDE5A/IGF1/SASH3/ADAM8/CBFB	60
BP	GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	34/2306	145/18670	0.0001488	0.004422	0.003402	NFKBIZ/ZC3H12A/TNFAIP3/IL6/IL1B/RIPK2/IL33/IL7R/RSAD2/C3/TNFRSF1B/TNFSF13B/HLA-E/IL12A/IL18R1/IL4R/HLA-F/CD40/FADD/HLA-A/ADA/EXOSC6/CLCF1/STAT6/MEF2C/TRAF2/HAVCR2/TNF/GATA3/HLA-G/P2RX7/HLA-B/SASH3/HLA-H	34
BP	GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	26/2306	100/18670	0.0001505	0.00445	0.003424	NFKBIZ/IL6/IL1B/RIPK2/RSAD2/C3/TNFSF13B/HLA-E/IL12A/IL18R1/HLA-F/CD40/FADD/HLA-A/ADA/EXOSC6/CLCF1/STAT6/TRAF2/TNF/GATA3/HLA-G/P2RX7/HLA-B/SASH3/HLA-H	26
BP	GO:0045137	development of primary sexual characteristics	47/2306	223/18670	0.0001533	0.004462	0.003433	ICAM1/CITED2/KIT/CEBPB/BASP1/ARID5B/VEGFA/EREG/RAB13/PDGFRB/AFP/IRX5/BCL2L2/RDH10/SLIT2/CCND1/IDH1/HOXA11/LHX8/HOXA10/SRD5A1/INHBB/LHFPL2/TGFB2/GATA6/NUDT1/RHOBTB3/SIX4/SIRT1/WNT5A/NKX3-1/BCL2L1/MAMLD1/FZD4/EIF2B5/HOXA9/EIF2B4/TLR3/PTX3/GATA3/ZNF830/EIF2S2/UBB/OSR1/CYP19A1/CRKL/ARID4A	47
BP	GO:0010273	detoxification of copper ion	8/2306	15/18670	0.0001538	0.004462	0.003433	MT1G/MT1M/MT1E/MT1A/MT1X/MT2A/MT1H/MT1F	8
BP	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase	8/2306	15/18670	0.0001538	0.004462	0.003433	ACOX2/CROT/AMACR/ABCD1/DECR2/ACOT8/SCP2/ACOXL	8
BP	GO:1990169	stress response to copper ion	8/2306	15/18670	0.0001538	0.004462	0.003433	MT1G/MT1M/MT1E/MT1A/MT1X/MT2A/MT1H/MT1F	8
BP	GO:0030225	macrophage differentiation	15/2306	44/18670	0.0001554	0.004475	0.003443	CSF2/LIF/ID2/TRIB1/CSF1/PRKCA/VEGFA/BMP4/FADD/IL15/MMP9/SIRT1/CEBPA/CDC42/TSPAN2	15
BP	GO:0008406	gonad development	46/2306	217/18670	0.0001557	0.004475	0.003443	ICAM1/CITED2/KIT/CEBPB/BASP1/ARID5B/VEGFA/EREG/RAB13/PDGFRB/AFP/IRX5/BCL2L2/RDH10/SLIT2/CCND1/IDH1/HOXA11/LHX8/HOXA10/SRD5A1/INHBB/TGFB2/GATA6/NUDT1/RHOBTB3/SIX4/SIRT1/WNT5A/NKX3-1/BCL2L1/MAMLD1/FZD4/EIF2B5/HOXA9/EIF2B4/TLR3/PTX3/GATA3/ZNF830/EIF2S2/UBB/OSR1/CYP19A1/CRKL/ARID4A	46
BP	GO:0110111	negative regulation of animal organ morphogenesis	13/2306	35/18670	0.0001583	0.00453	0.003486	STAT1/BMP4/BMPR2/LIMS2/TGFB2/WNT5A/SULF1/TNF/TACSTD2/RSPO2/GATA3/TNFRSF11B/NFIB	13
BP	GO:0045862	positive regulation of proteolysis	69/2306	363/18670	0.0001599	0.004554	0.003504	ZC3H12A/BID/TNIP1/PSME2/IL1B/RIPK2/IL33/TRIB1/TRIB2/BAG2/DAB2/PRR7/PSME1/C3/TNFRSF1B/DAPK1/PDCD5/PLK2/CFLAR/NKD2/ANKIB1/FYN/HERPUD1/FAS/ARL6IP5/NUB1/MTCH1/DDA1/FADD/RNF14/TRIB3/MBP/PMAIP1/F2R/ARIH2/CSNK1E/SH3D19/ROBO1/ARIH1/TNP2/SIRT1/TRAF2/RCN3/NKX3-1/RNF144B/RGN/RAD23A/GSN/TNF/SOX7/TNFRSF10B/CEBPA/DET1/MAGEF1/ROCK2/BCL10/PPARG/PSME4/SH3RF2/FAM162A/MYH9/STAT3/DVL1/ADAM8/ZFAND2A/PICALM/OSBPL7/ST20/ADRA2A	69
BP	GO:0043666	regulation of phosphoprotein phosphatase activity	29/2306	117/18670	0.0001608	0.004558	0.003507	ITGA1/ENSA/PPP4R4/PPP1R15A/ROCK1/PPP2R1B/PDGFRB/SET/CALM1/PPP1R12A/SLC39A10/DMPK/PPP1R9B/PHACTR2/NUAK1/RCAN1/RGN/TNF/PPP2R5E/CALM2/FKBP1A/ANKLE2/ROCK2/PPP2R5C/PPP1R14C/PPP1R7/SH3RF2/RCAN2/SHOC2	29
BP	GO:2001234	negative regulation of apoptotic signaling pathway	48/2306	230/18670	0.0001681	0.004737	0.003644	SOD2/BID/ICAM1/TNFAIP3/PTGS2/CSF2/IL1B/BDKRB2/SH3RF1/HSPB1/IL1A/DNAJA1/CFLAR/BMP4/PPIF/BCL2L2/CD44/FYN/HERPUD1/FAS/LMNA/FADD/THBS1/TCF7L2/GRINA/NME5/SNAI2/YAP1/MMP9/SIRT1/TRAF2/BCL2L1/ACAA2/TNF/HYOU1/TNFRSF10B/IVNS1ABP/BIRC6/MAGEA3/TMEM14A/ITPRIP/SERPINE1/FGF10/IGF1/ITGA6/EYA2/SGK3/PELI3	48
BP	GO:0071349	cellular response to interleukin-12	16/2306	49/18670	0.0001686	0.004737	0.003644	SOD2/PSME2/SERPINB2/STAT4/CNN2/IL12A/GSTO1/SIRPA/PPIA/BOLA2/ARF1/TYK2/IL12RB2/MTAP/RALA/CDC42	16
BP	GO:0071621	granulocyte chemotaxis	30/2306	123/18670	0.0001702	0.004761	0.003663	CXCL1/CXCL2/CXCL6/CCL20/CCL5/CXCL5/IL1B/ITGA1/CXCL10/CCL2/CCL8/CSF1/CCL7/PIK3CD/PF4V1/JAM3/CCL3L3/CXCL3/CMKLR1/SLIT2/PDE4D/CXCL11/CCL3/THBS1/EDN1/CXCL9/CCL1/TGFB2/AKIRIN1/PDE4B	30
BP	GO:0016050	vesicle organization	63/2306	325/18670	0.000172	0.004789	0.003685	TAP1/TAP2/ABCA1/CHMP1B/SQSTM1/FNBP1L/SAMD9L/CORO1C/NKD2/PLEKHF1/BET1/RAB38/EPS15/SORT1/CHMP4B/VAMP4/STX3/STX6/TBC1D4/ANXA8/TGFA/VPS37D/SDCBP/VPS36/F2R/VPS37C/SRGN/SNAP47/RAB32/MYO18A/RAB3A/SHROOM2/SYT4/CCDC136/ARF1/TMEM175/SAMD9/HOOK3/DLG4/STXBP1/SYT1/CHMP5/SDC4/STX16/TMED9/ZPBP2/TRAPPC4/TMED10/VAMP7/TAPBP/TSNARE1/CNIH2/PI4K2B/TRAPPC9/AKTIP/P2RX7/SERPINA1/ANKRD27/PDCD6IP/RFX2/PICALM/SNX3/SNX10	63
BP	GO:0010631	epithelial cell migration	67/2306	351/18670	0.0001741	0.004825	0.003712	ZC3H12A/PTGS2/HSPB1/KIT/FGF2/PRKCA/MCC/CORO1C/VEGFA/PLK2/BMP4/RAB13/CD40/SLIT2/RHOJ/IQSEC1/ETS1/NR2F2/BMPR2/EPB41L4B/KLF4/THBS1/EDN1/KRT16/BMPER/PXN/CARD10/HBEGF/RHOB/PIK3R3/TGFB2/ITGA2/HAS2/STARD13/MMP9/MEOX2/AMOTL1/ROBO1/MEF2C/SIRT1/MIR19B2/WNT5A/ARF6/KRT2/PFN2/MIR137/SPARC/TACSTD2/PTPRM/PLXND1/SP100/GATA3/RTN4/MAPRE2/ABL1/ROCK2/LGALS8/DUSP10/PPARG/PTPN11/FGF10/PKN2/FERMT1/MYH9/MIR199A2/GLIPR2/ATOH8	67
BP	GO:1903426	regulation of reactive oxygen species biosynthetic process	26/2306	101/18670	0.0001792	0.00494	0.003801	ZC3H12A/ICAM1/PTGS2/IL1B/DDAH1/CFLAR/KLF2/FYN/PKD2/KLF4/CYBA/GLA/EDN1/SIRPA/ABCD1/RGN/TNF/ASS1/DDAH2/PTX3/ROCK2/HBB/SLC25A33/TICAM1/MIR199A2/STAT3	26
BP	GO:0070527	platelet aggregation	18/2306	59/18670	0.0001799	0.00494	0.003801	HSPB1/C1QTNF1/PRKCA/PDPN/SLC7A11/VCL/UBASH3B/ABAT/ACTB/STXBP1/PEAR1/PRKCD/HBB/GAS6/MYH9/ACTG1/TLN1/MYL12A	18
BP	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	49/2306	237/18670	0.0001832	0.005008	0.003853	BIRC3/ZC3H12A/TNFAIP3/TNIP1/IL1B/RIPK2/HSPB1/SQSTM1/BIRC2/TNIP3/STAT1/IRAK4/PLK2/CFLAR/TSPAN6/TRIM25/CD40/FYN/PIM2/TIFA/TRAF3IP2/FADD/NDFIP1/ROR1/SIRPA/F2R/CXXC5/LPAR1/SIRT1/OPTN/WNT5A/TRAF2/TNF/TNFRSF10B/FKBP1A/UBD/TLR3/NEK6/ABL1/RBCK1/BCL10/PER1/NDFIP2/TLE1/TICAM1/TRIM38/TMEM101/MAPKBP1/PELI2	49
BP	GO:2001057	reactive nitrogen species metabolic process	23/2306	85/18670	0.0001872	0.005097	0.003921	ZC3H12A/ICAM1/PTGS2/IL1B/SLC7A2/DDAH1/KLF2/PKD2/KLF4/GCH1/GLA/EDN1/SIRPA/RGN/TNF/ASS1/DDAH2/PTX3/CPS1/ROCK2/HBB/TICAM1/MIR199A2	23
BP	GO:1990266	neutrophil migration	29/2306	118/18670	0.0001884	0.005106	0.003929	CXCL1/CXCL2/CXCL6/CCL20/CCL5/CXCL5/IL1B/ITGA1/CXCL10/CCL2/CCL8/CCL7/PIK3CD/PF4V1/IRAK4/JAM3/CCL3L3/CXCL3/SLIT2/PDE4D/CXCL11/CCL3/EDN1/CXCL9/CCL1/TGFB2/SLAMF8/PDE4B/ADAM8	29
BP	GO:0097530	granulocyte migration	33/2306	141/18670	0.0001919	0.005178	0.003984	CXCL1/CXCL2/CXCL6/CCL20/CCL5/CXCL5/IL1B/ITGA1/CXCL10/CCL2/CCL8/CSF1/CCL7/PIK3CD/PF4V1/IRAK4/JAM3/CCL3L3/CXCL3/CMKLR1/SLIT2/PDE4D/CXCL11/CCL3/THBS1/EDN1/CXCL9/CCL1/TGFB2/AKIRIN1/SLAMF8/PDE4B/ADAM8	33
BP	GO:0043502	regulation of muscle adaptation	27/2306	107/18670	0.0001943	0.005221	0.004017	PPARGC1A/PRKCA/JARID2/TNFRSF1B/FOXO1/IL6ST/ROCK1/PAK1/CAMK2D/KLF4/LMNA/LMCD1/EDN1/RGS2/ERRFI1/MIR19B2/RGS4/CAMK2G/ATP2A2/MIR1-2/PPP3CA/ROCK2/MIR214/PDE5A/MIR199A2/IGF1/CASQ1	27
BP	GO:0051608	histamine transport	7/2306	12/18670	0.0001953	0.005222	0.004018	CSF2/SNX4/ADA/EDN1/SLC22A3/VAMP7/NPPA	7
BP	GO:0010256	endomembrane system organization	80/2306	438/18670	0.0001967	0.005222	0.004018	ABCA1/CHMP1B/LPIN1/SQSTM1/ATP8B1/PRKCA/FNBP1L/TRAM2/ZFYVE27/PLSCR1/CORO1C/MYOF/COG2/PLEKHF1/RAB38/UGCG/CHMP4B/VAMP4/STX6/ANK3/LMNA/SGIP1/A4GALT/ANXA8/MICALL1/RAB3GAP1/DMPK/VPS37D/GCC2/VPS36/EPB41L3/F2R/VPS37C/DCTN1/TGFB2/TLCD1/SYPL2/FLOT1/ABCD1/SRGN/OPTN/MYO18A/RAB3A/SYT4/CCDC136/RAB18/GSN/ATL1/BIN3/SYTL4/HOOK3/ATP2A2/ASAP1/NEK6/PARP11/GOLGA8G/PRKCD/ANKLE2/ARHGAP21/CHMP5/RTN4/STX16/TMED9/ZPBP2/TOR1A/TMED10/PLSCR2/CDC42/MYH9/PI4K2B/MYH10/AKTIP/P2RX7/TMEM33/COL5A1/CASQ1/PDCD6IP/RFX2/SNX3/SNX10	80
BP	GO:0090263	positive regulation of canonical Wnt signaling pathway	34/2306	147/18670	0.0001969	0.005222	0.004018	PSME2/NFKB1/PSMA6/PSMB10/RECK/PSMB8/PSMB7/PSME1/PSMB9/COL1A1/PSMA3/SULF2/UBR5/ARNTL/CSNK1G2/YAP1/CSNK1E/DAAM2/PSMA1/PSMB2/VPS35/PSMB3/PTK7/RSPO2/JRK/PSMA8/LGR4/FGF10/PSME4/PSMB5/CSNK1G3/TBL1XR1/PLEKHA4/PSMF1	34
BP	GO:0030168	platelet activation	35/2306	153/18670	0.0002009	0.00526	0.004047	IL6/HSPB1/C1QTNF1/PRKCA/PDPN/PLSCR1/PF4V1/SLC7A11/VCL/COL1A1/CD40/FYN/VWF/UBASH3B/F2R/GNA13/GNA12/AXL/ITPR2/ABAT/DGKI/ACTB/STXBP1/PEAR1/PRKCD/COL1A2/HBB/GAS6/PTPN11/MYH9/ACTG1/TLN1/MYL12A/ADRA2A/GNG2	35
BP	GO:0042133	neurotransmitter metabolic process	35/2306	153/18670	0.0002009	0.00526	0.004047	ZC3H12A/ICAM1/PTGS2/IL1B/SLC7A2/DDAH1/SLC22A2/KLF2/PKD2/KLF4/GCH1/GLA/EDN1/SRD5A1/HNMT/SIRPA/PRG3/MOXD1/DAGLA/RGN/AMT/ALDH7A1/ABAT/TNF/ASS1/DAGLB/DDAH2/ALDH5A1/PTX3/PHGDH/CPS1/ROCK2/HBB/TICAM1/MIR199A2	35
BP	GO:0050729	positive regulation of inflammatory response	35/2306	153/18670	0.0002009	0.00526	0.004047	NFKBIZ/NFKBIA/PTGS2/IL6/TNIP1/IL1B/IL33/C2CD4B/CEBPB/OSMR/C3/IDO1/IL6ST/GBP5/HLA-E/CCL3L3/ETS1/CCL3/SNX4/IL15/IL17RB/MAPK13/CCL1/ITGA2/ABCC1/WNT5A/TNF/TLR3/CEBPA/SERPINE1/VAMP7/NPPA/TICAM1/MGST2/ADAM8	35
BP	GO:0038061	NIK/NF-kappaB signaling	40/2306	183/18670	0.0002074	0.00537	0.004132	NFKBIA/BIRC3/ZC3H12A/PSME2/IL1B/RELB/PSMA6/NFKB2/PSMB10/BIRC2/PSMB8/PSMB7/PSME1/PSMB9/IL18R1/TSPAN6/PSMA3/TRIP6/ZFP91/CYLD/EDN1/CARD10/PPP4C/PSMA1/BCL3/PSMB2/TRAF2/PSMB3/HAVCR2/TNF/TNFRSF10B/ACTN4/MIR125B1/TLR3/PSMA8/RBCK1/PYDC2/PSME4/PSMB5/PSMF1	40
BP	GO:0043487	regulation of RNA stability	40/2306	183/18670	0.0002074	0.00537	0.004132	ZC3H12A/PSME2/PSMA6/HSPB1/PSMB10/PSMB8/PRKCA/PSMB7/PSME1/TNFRSF1B/ROCK1/PSMB9/SET/MOV10/FTO/PSMA3/ZFP36/EXOSC6/ZFP36L2/CSDC2/HNRNPA0/PDE12/DCP1A/PSMA1/PSMB2/PABPC1/SERBP1/SAMD4B/PSMB3/SYNCRIP/PRKCD/PSMA8/FASTKD3/ROCK2/FXR2/UBB/ANGEL2/PSME4/PSMB5/PSMF1	40
BP	GO:0043488	regulation of mRNA stability	39/2306	177/18670	0.0002077	0.00537	0.004132	ZC3H12A/PSME2/PSMA6/HSPB1/PSMB10/PSMB8/PRKCA/PSMB7/PSME1/ROCK1/PSMB9/SET/MOV10/FTO/PSMA3/ZFP36/EXOSC6/ZFP36L2/CSDC2/HNRNPA0/PDE12/DCP1A/PSMA1/PSMB2/PABPC1/SERBP1/SAMD4B/PSMB3/SYNCRIP/PRKCD/PSMA8/FASTKD3/ROCK2/FXR2/UBB/ANGEL2/PSME4/PSMB5/PSMF1	39
BP	GO:0071375	cellular response to peptide hormone stimulus	62/2306	321/18670	0.0002138	0.005506	0.004236	PID1/IL1B/NFKB1/LPIN1/FOXO1/PTPRE/STAT1/EEF2K/AGTRAP/ROCK1/CFLAR/ATP6V1E2/RAB13/PAK1/SOCS1/SOCS3/ATP6V0B/FYN/IRS1/GRB14/TBC1D4/ATP6V0E2/CYBA/PIK3R2/TRIB3/EDN1/SRD5A1/PXN/INHBB/ENPP1/GHR/ADCY7/PIK3R3/KAT2B/ERRFI1/SESN3/GJB2/ADCY9/ADCY3/STAT6/SIRT1/GDF15/FBN1/BGLAP/ASS1/APPL2/SOCS2/PRKCD/CPS1/ROCK2/NUCKS1/PDE3B/MAX/SLC25A33/AP3S1/PPARG/PTPN11/NCOA5/STAT3/RAB31/ATP6V1E1/FOXO4	62
BP	GO:0090130	tissue migration	68/2306	360/18670	0.0002148	0.005509	0.004238	ZC3H12A/PTGS2/HSPB1/KIT/FGF2/PRKCA/MCC/CORO1C/VEGFA/PLK2/BMP4/RAB13/CD40/SLIT2/RHOJ/IQSEC1/ETS1/NR2F2/BMPR2/EPB41L4B/KLF4/THBS1/ACTC1/EDN1/KRT16/BMPER/PXN/CARD10/HBEGF/RHOB/PIK3R3/TGFB2/ITGA2/HAS2/STARD13/MMP9/MEOX2/AMOTL1/ROBO1/MEF2C/SIRT1/MIR19B2/WNT5A/ARF6/KRT2/PFN2/MIR137/SPARC/TACSTD2/PTPRM/PLXND1/SP100/GATA3/RTN4/MAPRE2/ABL1/ROCK2/LGALS8/DUSP10/PPARG/PTPN11/FGF10/PKN2/FERMT1/MYH9/MIR199A2/GLIPR2/ATOH8	68
BP	GO:0070534	protein K63-linked ubiquitination	16/2306	50/18670	0.0002198	0.005613	0.004319	BIRC2/ITCH/ZFP91/UBR5/ARIH2/HECTD1/RNF5/TRAF2/UBE2T/RNF4/RNF126/NEDD4/BFAR/MAGEL2/UBE2S/PELI3	16
BP	GO:0090132	epithelium migration	67/2306	354/18670	0.0002245	0.005703	0.004387	ZC3H12A/PTGS2/HSPB1/KIT/FGF2/PRKCA/MCC/CORO1C/VEGFA/PLK2/BMP4/RAB13/CD40/SLIT2/RHOJ/IQSEC1/ETS1/NR2F2/BMPR2/EPB41L4B/KLF4/THBS1/EDN1/KRT16/BMPER/PXN/CARD10/HBEGF/RHOB/PIK3R3/TGFB2/ITGA2/HAS2/STARD13/MMP9/MEOX2/AMOTL1/ROBO1/MEF2C/SIRT1/MIR19B2/WNT5A/ARF6/KRT2/PFN2/MIR137/SPARC/TACSTD2/PTPRM/PLXND1/SP100/GATA3/RTN4/MAPRE2/ABL1/ROCK2/LGALS8/DUSP10/PPARG/PTPN11/FGF10/PKN2/FERMT1/MYH9/MIR199A2/GLIPR2/ATOH8	67
BP	GO:0010876	lipid localization	74/2306	400/18670	0.0002253	0.005703	0.004387	NFKBIA/ZC3H12A/IL6/IL1B/KCNN4/NFKB1/BDKRB2/OSBPL10/ABCA1/PITPNC1/ATP8B1/C1QTNF1/TEX2/SLC27A3/C3/PLA2G4A/OSBPL1A/AQP9/ESYT1/PLIN2/ACACB/MYB/LIMA1/FABP3/RXRA/FTO/UGCG/THBS1/CROT/EDN1/ENPP1/LIPG/CPT1A/ACACA/STOML1/ABCA5/ABCC1/NPC1L1/APOL6/SOAT1/EHD1/PLEKHA3/ABCD1/PLA2G12A/SIRT1/MIR19B2/OSBPL3/ABCC2/TNFAIP8L3/NKX3-1/OSBPL5/TNF/SLC25A20/CLN8/FZD4/ATP8A2/ABHD5/PRKAB2/PRKCD/SCP2/VAMP7/PPARG/PTPN11/SIGMAR1/NMUR2/P2RX7/APOL4/GULP1/TMEM30B/MID1IP1/CYP19A1/OSBPL7/GRAMD1A/STARD7	74
BP	GO:0048013	ephrin receptor signaling pathway	23/2306	86/18670	0.0002261	0.005703	0.004387	ARPC1A/SIPA1L1/ROCK1/PAK1/ACTR3/FYN/SDCBP/SDC2/CHN1/APH1B/MMP9/EFNB1/ARPC2/PSENEN/ACTB/ROCK2/PTPN11/EPHA1/ACTR2/ANKS1A/CDC42/ACTG1/NGEF	23
BP	GO:0050852	T cell receptor signaling pathway	43/2306	202/18670	0.0002277	0.00572	0.004401	NFKBIZ/ZC3H12A/PSME2/RIPK2/KCNN4/NFKB1/PSMA6/PSMB10/PSMB8/PIK3CD/PSMB7/PSME1/BTN3A1/PAK1/PSMB9/FYN/PDE4D/PSMA3/GBP1/BTN2A1/PIK3R2/CYLD/ADA/BTN3A3/DUSP3/PSMA1/PSMB2/PSMB3/CACNA1F/EIF2B5/EIF2B4/PVRIG/GATA3/PSMA8/HLA-DQB1/ABL1/RBCK1/BCL10/PDE4B/PSME4/PSMB5/CRKL/PSMF1	43
BP	GO:0046916	cellular transition metal ion homeostasis	27/2306	108/18670	0.000229	0.00573	0.004409	SLC39A14/MT1G/MT1M/MT1E/MT1A/MT1X/SLC11A2/MT2A/ACO1/MT1H/MT1F/FTH1/SLC39A10/NDFIP1/SLC39A8/SLC30A9/CAND1/SLC30A7/ABCG2/ARF1/SLC30A1/HMOX2/CYBRD1/FTHL17/FBXL5/ATP13A2/SRI	27
BP	GO:0043406	positive regulation of MAP kinase activity	52/2306	258/18670	0.0002302	0.005731	0.004409	BMP2/IRAK2/MAP3K8/IL1B/RIPK2/ITGA1/ERN1/TPD52L1/KIT/FGF2/DAXX/PLCE1/DUSP6/VEGFA/BMP4/PAK1/PDGFRB/CD40/THBS1/KIDINS220/MAP3K1/EDN1/TGFA/GHR/PDGFD/F2R/LPAR1/GADD45G/ROBO1/FZD8/WNT5A/TRAF2/ADORA1/GDF15/ARHGEF5/TNF/MAP3K2/MLKL/FZD4/PDGFC/UBB/PTPN11/FGF10/DUSP5/PDE5A/IGF1/DVL2/P2RX7/TAOK1/ADAM8/CRKL/ADRA2A	52
BP	GO:1990868	response to chemokine	25/2306	97/18670	0.0002318	0.005731	0.004409	CXCL1/CXCL2/CXCL6/CCL20/ZC3H12A/CCL5/CXCL5/CXCL10/CCL2/CCL8/CCL7/PF4V1/CCL3L3/CXCL3/CMKLR1/SLIT2/CXCL11/CCL3/SLC12A2/EDN1/CXCL9/CCL1/ROBO1/RBM15/CCR10	25
BP	GO:1990869	cellular response to chemokine	25/2306	97/18670	0.0002318	0.005731	0.004409	CXCL1/CXCL2/CXCL6/CCL20/ZC3H12A/CCL5/CXCL5/CXCL10/CCL2/CCL8/CCL7/PF4V1/CCL3L3/CXCL3/CMKLR1/SLIT2/CXCL11/CCL3/SLC12A2/EDN1/CXCL9/CCL1/ROBO1/RBM15/CCR10	25
BP	GO:0097696	STAT cascade	37/2306	166/18670	0.000234	0.005758	0.00443	AKR1B1/CCL5/IL6/CSF2/LIF/CCL2/STAT4/PARP14/IFNAR2/KIT/IFNAR1/IL7R/STAT1/IL6ST/IL12A/SOCS1/SOCS3/CD40/FYN/PKD2/IL26/IL15/GHR/F2R/STAT2/CLCF1/STAT6/PARP9/BCL3/MIR19B2/HES5/TNF/MIR125B1/SOCS2/IGF1/STAT3/ARL2BP	37
BP	GO:0090090	negative regulation of canonical Wnt signaling pathway	39/2306	178/18670	0.0002348	0.005758	0.00443	BMP2/PSME2/PSMA6/PSMB10/DAB2/PSMB8/PSMB7/PSME1/FOXO1/MCC/ANKRD6/LZTS2/NKD2/PSMB9/WWTR1/FZD1/LATS2/PSMA3/CYLD/STK4/TCF7L2/TMEM64/SNAI2/WNT5B/PSMA1/PSMB2/DACT3/WNT5A/PSMB3/MIR1-2/PSMA8/TLE1/PSME4/FERMT1/PSMB5/DVL1/DVL2/SDHAF2/PSMF1	39
BP	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	22/2306	81/18670	0.0002415	0.005875	0.00452	IL33/TRIB1/TRIB2/DAB2/PLK2/NKD2/ANKIB1/HERPUD1/NUB1/DDA1/RNF14/TRIB3/ARIH2/CSNK1E/ARIH1/RNF144B/RAD23A/CEBPA/DET1/SH3RF2/DVL1/ZFAND2A	22
BP	GO:0110110	positive regulation of animal organ morphogenesis	22/2306	81/18670	0.0002415	0.005875	0.00452	BMP2/TNFAIP3/LIF/CSF1/BASP1/SIX1/VEGFA/CFLAR/BMP4/HOXA11/PIM1/EDN1/TGFB2/SPRY1/SIX4/ROBO1/VDR/GATA3/HOXB7/LGR4/ENG/FGF10	22
BP	GO:0072088	nephron epithelium morphogenesis	21/2306	76/18670	0.0002559	0.006202	0.004772	BMP2/LIF/AHI1/FGF2/SIX1/STAT1/KLHL3/VEGFA/LZTS2/BMP4/IRX3/PKD2/HOXA11/SIX4/HES5/PGF/TACSTD2/GATA3/HOXB7/LGR4/OSR1	21
BP	GO:0060326	cell chemotaxis	59/2306	304/18670	0.0002631	0.006352	0.004887	CXCL1/CXCL2/CXCL6/CCL20/CCL5/IL6/CH25H/CXCL5/VCAM1/IL1B/ITGA1/CXCL10/CCL2/CCL8/HSPB1/CSF1/CCL7/KIT/FGF2/PIK3CD/PF4V1/VEGFA/RAB13/JAM3/PDGFRB/IL12A/CCL3L3/CXCL3/CMKLR1/SLIT2/PDE4D/CXCL11/CCL3/THBS1/SLC12A2/EDN1/CXCL9/HBEGF/PDGFD/CCL1/TGFB2/LPAR1/ABCC1/AKIRIN1/WNT5A/ARHGEF5/HSD3B7/PGF/SLAMF8/DOCK4/CNR2/PRKCD/SERPINE1/PDE4B/GAS6/CCR10/ADAM8/CYP19A1/CRKL	59
BP	GO:0032956	regulation of actin cytoskeleton organization	65/2306	343/18670	0.0002664	0.006405	0.004928	ICAM1/FSCN1/ASAP3/ARPC1A/DBN1/ROCK1/ARHGEF10/PAK1/JAM3/PDGFRB/PPFIA1/CDC42EP1/ARHGAP18/LIMA1/ACTR3/CDC42EP3/SLIT2/RHOJ/MYADM/ARHGAP28/CCDC88A/FMN2/EDN1/RDX/PXN/DSTN/DIXDC1/RHOB/PLEKHH2/LPAR1/RHOBTB3/FHOD1/RHOU/MEF2C/PHLDB2/ARPC2/CDK5/RGS4/CAPZA2/ARF6/ARF1/PFN2/ARHGEF5/EPS8/GSN/SH3PXD2B/TACSTD2/MIR1-2/PRKCD/SDC4/GMFB/ABL1/ROCK2/MIR214/PDXP/ARHGDIB/EPHA1/ACTR2/TMOD2/CDC42/SERPINF2/TAOK1/PLEKHG2/MAGEL2/WASF2	65
BP	GO:0032480	negative regulation of type I interferon production	15/2306	46/18670	0.0002721	0.006517	0.005014	TNFAIP3/RELB/IFIH1/UBE2L6/ISG15/TRIM25/DDX58/ITCH/UBA7/CYLD/DHX58/SIRPA/HAVCR2/HERC5/TAX1BP1	15
BP	GO:0050848	regulation of calcium-mediated signaling	25/2306	98/18670	0.0002752	0.006567	0.005053	GSTO1/CMKLR1/CALM1/PDE4D/CAMK2D/PKD2/CCL3/GBP1/FHL2/DYRK2/LMCD1/ADA/RCAN1/TMBIM4/RGN/P2RX3/TNF/CALM2/FKBP1A/RCAN2/IGF1/SRI/HINT1/HOMER2/CHP2	25
BP	GO:0007159	leukocyte cell-cell adhesion	64/2306	337/18670	0.0002781	0.006611	0.005087	NFKBIZ/ZC3H12A/ICAM1/CCL5/IL6/TNIP1/CD70/VCAM1/MAP3K8/IL1B/CD83/RIPK2/CCL2/ADORA2A/IRF1/TNFSF9/CEBPB/IL7R/TNFRSF14/PDCD1LG2/IDO1/IL6ST/ROCK1/BMP4/TNFSF13B/PAK1/HLA-E/IL12A/MYB/IL4R/SOCS1/CD44/FYN/ETS1/LRRC32/KLF4/FADD/ITGA4/IL15/CYLD/ADA/MAD1L1/SEMA4D/SIRPA/EBI3/HAS2/DUSP3/EFNB1/HAVCR2/TNF/ASS1/GCNT1/GATA3/HLA-G/SDC4/BCL10/DUSP10/PTPN11/CDC42/PDE5A/IGF1/SASH3/ADAM8/CBFB	64
BP	GO:0032963	collagen metabolic process	28/2306	115/18670	0.0002847	0.006742	0.005187	IL6/MMP1/MMP3/TRAM2/BMP4/PDGFRB/CTSS/MYB/COL1A1/F2R/ITGA2/ERRFI1/PLOD2/CYGB/MMP9/MMP17/MMP11/RCN3/MMP27/SERPINH1/COL1A2/MMP24/PPARG/ENG/MIR218-1/P2RX7/SERPINF2/COL5A1	28
BP	GO:0060688	regulation of morphogenesis of a branching structure	17/2306	56/18670	0.0002881	0.006796	0.005228	SIX1/VEGFA/BMP4/RXRA/SNAI2/SIX4/WNT5A/SULF1/TNF/PGF/TACSTD2/HOXB7/RTN4/LGR4/ABL1/FGF10/SIRT6	17
BP	GO:0051403	stress-activated MAPK cascade	56/2306	286/18670	0.0002949	0.006915	0.00532	BMP2/ZC3H12A/IRAK2/MAP3K8/IL1B/RIPK2/NFKB1/SH3RF1/TRIB1/ERN1/TPD52L1/DAXX/FOXO1/ANKRD6/VEGFA/DNAJA1/IRAK4/MID1/PAK1/FAS/ARL6IP5/IL26/ITCH/ZFP36/CYLD/EDN1/PRMT1/MAPK13/CRYAB/SDCBP/HIPK2/SIRPA/TGFB2/DUSP3/GADD45G/FZD8/WNT5A/TRAF2/ARHGEF5/TNF/MAP3K2/MLKL/FZD4/TLR3/DUSP10/UBB/PER1/PJA2/SH3RF2/GDF6/DVL2/SERPINF2/TAOK1/FZD7/CRKL/ZNF675	56
BP	GO:0055001	muscle cell development	40/2306	186/18670	0.0002965	0.006915	0.00532	FLNC/SIX1/MYOF/VEGFA/CFLAR/BMP4/PAK1/PDGFRB/LMNA/ACTC1/EDN1/MYOM1/SGCD/RGS2/SMYD3/SYPL2/SIX4/MEF2C/MIR19B2/RGS4/MYOM3/BIN3/PDLIM5/CHRNB1/ATP2A2/MIR1-2/KRT19/PPP3CA/TMOD2/MYH6/ENG/NPPA/MIR199A2/IGF1/MYH10/ACTG1/CASQ1/SGCB/DNER/TBX3	40
BP	GO:0030593	neutrophil chemotaxis	26/2306	104/18670	0.0002965	0.006915	0.00532	CXCL1/CXCL2/CXCL6/CCL20/CCL5/CXCL5/IL1B/ITGA1/CXCL10/CCL2/CCL8/CCL7/PIK3CD/PF4V1/JAM3/CCL3L3/CXCL3/SLIT2/PDE4D/CXCL11/CCL3/EDN1/CXCL9/CCL1/TGFB2/PDE4B	26
BP	GO:0007259	JAK-STAT cascade	35/2306	156/18670	0.0002982	0.006929	0.005331	AKR1B1/CCL5/IL6/CSF2/LIF/CCL2/STAT4/PARP14/IFNAR2/KIT/IFNAR1/STAT1/IL6ST/IL12A/SOCS1/SOCS3/CD40/FYN/PKD2/IL26/IL15/GHR/F2R/STAT2/CLCF1/STAT6/PARP9/BCL3/MIR19B2/HES5/TNF/SOCS2/IGF1/STAT3/ARL2BP	35
BP	GO:0034405	response to fluid shear stress	13/2306	37/18670	0.0003011	0.006944	0.005343	PTGS2/CSF2/ABCA1/CITED2/KLF2/PDGFRB/ETS1/PKD2/KLF4/HAS2/MEF2C/ASS1/P2RX7	13
BP	GO:0050691	regulation of defense response to virus by host	13/2306	37/18670	0.0003011	0.006944	0.005343	ZC3H12A/TNFAIP3/IL1B/STAT1/APOBEC3G/DDX58/TRAF3IP2/IL15/EIF2AK4/PARP9/MICB/TRIM6/APOBEC3F	13
BP	GO:0009110	vitamin biosynthetic process	10/2306	24/18670	0.0003065	0.007008	0.005392	IL1B/NFKB1/CYP27B1/PNPO/PSAT1/SNAI2/UBIAD1/VDR/RGN/TNF	10
BP	GO:0060602	branch elongation of an epithelium	9/2306	20/18670	0.0003073	0.007008	0.005392	SIX1/BMP4/RDH10/SPRY1/YAP1/SIX4/WNT5A/TNC/FGF10	9
BP	GO:0072234	metanephric nephron tubule development	9/2306	20/18670	0.0003073	0.007008	0.005392	LIF/STAT1/WWTR1/PKD2/ACAT1/YAP1/HES5/LGR4/OSR1	9
BP	GO:0002218	activation of innate immune response	61/2306	319/18670	0.000316	0.00718	0.005524	NFKBIA/BIRC3/TNFAIP3/IRAK2/TNIP1/PSME2/RELB/RIPK2/NFKB1/PSMA6/PSMB10/IRF1/IFIH1/BIRC2/PSMB8/RSAD2/PSMB7/PSME1/TNIP3/DDX60/IRAK4/IRF7/PAK1/CTSS/TRAF3/PSMB9/TSPAN6/IRAK3/FYN/TIFA/DDX58/PSMA3/FADD/CYBA/ITCH/CYLD/MAP3K1/DHX58/DMBT1/RAB11FIP2/FLOT1/PSMA1/PSMB2/WDFY1/PSMB3/HAVCR2/APPL2/TLR3/PRKCD/PSMA8/RTN4/LGR4/BCL10/UBB/MUC15/MUC17/PSME4/PJA2/TICAM1/PSMB5/PSMF1	61
BP	GO:0070098	chemokine-mediated signaling pathway	23/2306	88/18670	0.0003257	0.007368	0.005669	CXCL1/CXCL2/CXCL6/CCL20/CCL5/CXCL5/CXCL10/CCL2/CCL8/CCL7/PF4V1/CCL3L3/CXCL3/CMKLR1/SLIT2/CXCL11/CCL3/EDN1/CXCL9/CCL1/ROBO1/RBM15/CCR10	23
BP	GO:0002831	regulation of response to biotic stimulus	32/2306	139/18670	0.0003267	0.007368	0.005669	CXCL6/BIRC3/ZC3H12A/TNFAIP3/IL1B/RIPK2/TRIB1/BIRC2/PRKCA/STAT1/DDX60/TRAF3/IL12A/IFIT1/APOBEC3G/TSPAN6/DDX58/TRAF3IP2/CYBA/ITCH/IL15/EIF2AK4/DHX58/PARP9/OPTN/MICB/HAVCR2/HERC5/TRIM6/APOBEC3F/TRIM38/MAPKBP1	32
BP	GO:0042692	muscle cell differentiation	71/2306	385/18670	0.0003284	0.007378	0.005677	SOD2/BMP2/CXCL10/FLNC/KIT/SIX1/MYOF/VEGFA/EREG/CFLAR/BMP4/PAK1/POPDC2/PDGFRB/IL4R/RXRA/SORT1/LMNA/SMARCD3/ACTC1/EDN1/CXCL9/DMPK/MYOM1/SGCD/RGS2/SMYD3/GATA6/MORF4L2/SYPL2/FLOT1/EHD1/PLEKHO1/IFRD1/SIX4/MEF2C/SIRT1/MIR19B2/RGS4/GDF15/MYOM3/BIN3/PDLIM5/CHRNB1/ATP2A2/MIR1-2/MIR125B1/KRT19/ARID1A/PPP3CA/ABL1/ASF1A/TMOD2/MYH6/ENG/NPPA/FGF10/SIK1/CDC42/MYH9/MIR199A2/IGF1/MYH10/ACTG1/CASQ1/FZD7/SGCB/FOXO4/DNER/CAPN2/TBX3	71
BP	GO:0006635	fatty acid beta-oxidation	20/2306	72/18670	0.0003295	0.007378	0.005677	ACOX2/ACACB/HIBCH/IRS1/CROT/ACAT1/HADH/ACAT2/CPT1A/AMACR/ABCD1/SESN2/ACAA2/DECR2/LONP2/BDH2/ACOT8/SCP2/ACOXL/ACADM	20
BP	GO:0030595	leukocyte chemotaxis	46/2306	224/18670	0.0003325	0.007418	0.005707	CXCL1/CXCL2/CXCL6/CCL20/CCL5/IL6/CH25H/CXCL5/IL1B/ITGA1/CXCL10/CCL2/CCL8/CSF1/CCL7/KIT/PIK3CD/PF4V1/VEGFA/JAM3/IL12A/CCL3L3/CXCL3/CMKLR1/SLIT2/PDE4D/CXCL11/CCL3/THBS1/SLC12A2/EDN1/CXCL9/CCL1/TGFB2/AKIRIN1/WNT5A/ARHGEF5/HSD3B7/PGF/SLAMF8/CNR2/SERPINE1/PDE4B/GAS6/ADAM8/CYP19A1	46
BP	GO:0006790	sulfur compound metabolic process	69/2306	372/18670	0.0003339	0.007422	0.00571	ST3GAL1/PTGES/KYNU/MTHFD2L/SLC7A11/MAT2A/TPST1/ACACB/GSTO1/ELOVL5/B4GALT3/GSTA4/NFE2L1/VCAN/SCD/ELOVL7/CHST7/IDH1/DBI/NUDT7/ACAT1/PCYOX1/GLB1/PPT1/ACSF2/SLC19A3/ENPP1/GHR/ACACA/ACSL5/CBR4/CSGALNACT1/AADAT/CSGALNACT2/CHAC2/ELOVL2/ABCD1/GAMT/SULT1C4/HAGH/BOLA2/ABCC2/PPCS/HSD17B12/MTR/ESD/NUBPL/PDHB/BHMT2/ADO/PAPSS1/CHST8/ALDH5A1/PHGDH/MTAP/CPS1/MMS19/ST3GAL3/GLRX2/PDK3/CNDP2/ACOT8/SUCLA2/FAR1/MGST2/GNMT/SULT2B1/ELOVL3/ST3GAL4	69
BP	GO:0043087	regulation of GTPase activity	85/2306	479/18670	0.0003372	0.007468	0.005746	CCL20/ICAM1/CCL5/TBC1D2/CCL2/CCL8/CCL7/ASAP3/SIPA1L1/CORO1C/ARHGEF10/RIN3/CCL3L3/ARHGAP18/CD40/FICD/NEDD9/SLIT2/IQSEC1/NET1/CCL3/TBC1D4/ARHGAP28/RDX/RAB3GAP1/RABGAP1/RINL/SH3BP4/STMN3/SEMA4D/F2R/TBC1D22B/CCL1/RAB11FIP2/RGS2/FGD4/SPRY1/CHN1/ERRFI1/RSU1/RGS16/FGD1/STARD13/ZC3H15/WNT5A/EVI5L/RGS4/ARHGAP1/RGS7/RGN/RIN2/RANBP3L/FAM13B/ARHGEF5/DGKI/TIAM2/ARHGAP10/DOCK4/STXBP5/PLXND1/ARHGEF12/RALBP1/PKP4/GDI1/ASAP1/ARHGAP24/ARHGAP21/MAPRE2/PLEKHG4/TBC1D9B/TBC1D19/SBF2/ARHGDIB/EPHA1/TBC1D10C/RIN1/TBC1D8/ITGA6/DVL2/NGEF/SBF1/ANKRD27/CRKL/PICALM/ASAP2	85
BP	GO:0120032	regulation of plasma membrane bounded cell projection assembly	38/2306	175/18670	0.0003386	0.007474	0.00575	ICAM1/PLD1/FSCN1/KIT/ATP8B1/FNBP1L/CORO1C/AUTS2/CDC42EP1/CDC42EP3/SLIT2/CCDC88A/CYLD/DYNC2LI1/RDX/DPYSL3/PODXL/TCHP/AKIRIN1/ARPC2/EVI5L/ARF6/PFN2/EPS8/BIN3/DYNLL1/TACSTD2/PLEK2/PRKCD/MARK4/MIR214/MYO10/RALA/MNS1/CDC42/SH3YL1/P2RX7/WASF2	38
BP	GO:0019722	calcium-mediated signaling	45/2306	218/18670	0.0003405	0.007489	0.005762	CCL20/VCAM1/PPP3CC/PLCE1/GSTO1/PTGFR/CMKLR1/CALM1/P2RY11/PDE4D/CAMK2D/PKD2/CCL3/GBP1/FHL2/DYRK2/LMCD1/ADA/EDN1/DMPK/PPP1R9B/SGCD/RCAN1/TMBIM4/RGN/CAMKK2/P2RX3/TNF/CALM2/ATP2A2/MIR1-2/FKBP1A/PPP3CA/SAMD14/MCOLN1/NMUR2/RCAN2/IGF1/CCR10/SRI/P2RX7/HINT1/CASQ1/HOMER2/CHP2	45
BP	GO:0062012	regulation of small molecule metabolic process	82/2306	459/18670	0.0003426	0.007509	0.005777	BMP2/PTGS2/PSME2/PID1/IL1B/NFKB1/PSMA6/PSMB10/PPARGC1A/KIT/C1QTNF1/PSMB8/SLC2A6/PSMB7/PSME1/FOXO1/INSIG2/SLC7A11/GIP/PPP1R3F/ACACB/PSMB9/ELOVL5/COX11/PPIF/RDH10/FABP3/IRS1/NUP133/NFE2L1/PSMA3/SCD/DYRK2/TRIB3/CYP27B1/TM7SF2/PHLDA2/ENPP1/PMAIP1/CLTC/CPT1A/ACACA/KAT2B/SNAI2/ADIPOR2/PDE12/HAS2/DNAJC15/PSMA1/ABCD1/PSMB2/VDR/SIRT1/COQ3/RGN/PSMB3/SESN2/TNF/APPL2/DUSP12/GPAM/PRKAB2/LONP2/ME1/PSMA8/NCOR2/PDK3/SLC25A33/PPARG/IDI1/SLC35B4/SIK1/PSME4/NUP35/PSMB5/IGF1/GNMT/STAT3/P2RX7/MID1IP1/SIRT6/PSMF1	82
BP	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	29/2306	122/18670	0.0003458	0.007525	0.00579	IL33/TRIB1/TRIB2/DAB2/PLK2/NKD2/RAD23B/ANKIB1/HERPUD1/NUB1/DDA1/RNF14/TRIB3/SDCBP/ARIH2/MAP1A/CSNK1E/GNA12/ARIH1/ARAF/RNF144B/RAD23A/UBXN1/USP14/CEBPA/DET1/SH3RF2/DVL1/ZFAND2A	29
BP	GO:1903409	reactive oxygen species biosynthetic process	29/2306	122/18670	0.0003458	0.007525	0.00579	ZC3H12A/ICAM1/PTGS2/IL1B/SLC7A2/DDAH1/CFLAR/KLF2/FYN/PKD2/KLF4/CYBA/GCH1/GLA/EDN1/SIRPA/CYP1A2/ABCD1/RGN/TNF/ASS1/DDAH2/PTX3/ROCK2/HBB/SLC25A33/TICAM1/MIR199A2/STAT3	29
BP	GO:0007009	plasma membrane organization	26/2306	105/18670	0.0003485	0.007557	0.005814	FNBP1L/PLSCR1/MYOF/UGCG/ANK3/SGIP1/A4GALT/MICALL1/EPB41L3/TGFB2/TLCD1/SYPL2/FLOT1/ABCD1/RAB3A/GSN/BIN3/SYTL4/ATP2A2/ASAP1/PRKCD/PLSCR2/MYH9/MYH10/P2RX7/COL5A1	26
BP	GO:0042509	regulation of tyrosine phosphorylation of STAT protein	22/2306	83/18670	0.0003516	0.007598	0.005846	CCL5/IL6/CSF2/LIF/PARP14/KIT/IL6ST/IL12A/SOCS1/SOCS3/CD40/FYN/IL15/GHR/CLCF1/PARP9/MIR19B2/HES5/TNF/IGF1/STAT3/ARL2BP	22
BP	GO:0002791	regulation of peptide secretion	88/2306	500/18670	0.0003533	0.007606	0.005852	ZC3H12A/TNFAIP3/CCL5/IL6/IL1B/RIPK2/IL33/KCNN4/ENSA/ADORA2A/IL1A/IFIH1/IFNGR1/PRKCA/TNFRSF14/RSAD2/TNFRSF1B/SLC2A1/PANX1/GIP/HLA-E/IL4R/SOCS1/CD58/CD40/LRRC32/IRS1/DDX58/IL26/PANX2/CCL3/GBP1/IL17RB/GLUD1/RHBDF2/HADH/AKAP12/GSDMD/TCF7L2/MBP/INHBB/MYOM1/ARNTL/F2R/CPT1A/CCL1/TGFB2/SERGEF/PPIA/LRP5/ITPR2/SRGN/WNT5A/TRAF2/ADORA1/KCNB1/VPS35/ANXA4/MYO18A/ARF6/SYT4/ARF1/ABAT/HAVCR2/TNF/SYTL4/DYNLL1/BRSK2/SERPINB1/TRIM6/GATA3/PPP3CA/LGR4/ABL1/RAB11FIP1/GAS6/PTPN11/PYDC2/FERMT1/ATP13A2/IGF1/MYH10/ARL2BP/SRI/P2RX7/MAPKBP1/ADAM8/ADRA2A	88
BP	GO:0035722	interleukin-12-mediated signaling pathway	15/2306	47/18670	0.0003544	0.007606	0.005852	SOD2/PSME2/SERPINB2/STAT4/CNN2/IL12A/GSTO1/PPIA/BOLA2/ARF1/TYK2/IL12RB2/MTAP/RALA/CDC42	15
BP	GO:2001233	regulation of apoptotic signaling pathway	74/2306	406/18670	0.0003569	0.007632	0.005872	SOD2/BID/ICAM1/TNFAIP3/PTGS2/CSF2/IL1B/PPP3CC/BDKRB2/SH3RF1/ADORA2A/HSPB1/IL1A/TPD52L1/PRR7/G0S2/PDCD5/DNAJA1/CFLAR/BMP4/PPP2R1B/PPIF/PLEKHF1/BCL2L2/CD44/FYN/HERPUD1/FAS/LMNA/BCLAF1/FADD/THBS1/CYLD/STK4/TCF7L2/INHBB/PMAIP1/GRINA/NME5/SNAI2/YAP1/MMP9/DEDD2/SIRT1/TRAF2/NKX3-1/BCL2L1/TP63/ACAA2/PRKRA/GSN/TNF/YWHAH/HYOU1/TNFRSF10B/IVNS1ABP/SP100/BIRC6/MAGEA3/PRKCD/TMEM14A/ITPRIP/SERPINE1/RBCK1/BCL10/UBB/FGF10/TFDP1/FAM162A/IGF1/ITGA6/EYA2/SGK3/PELI3	74
BP	GO:0051098	regulation of binding	69/2306	373/18670	0.0003612	0.007698	0.005923	NFKBIA/BMP2/LIF/RIPK2/ID2/BAG2/DAB2/ROCK1/PLK2/BMP4/GREM2/IFIT1/ZFP90/PIM2/KLF4/EDF1/ARHGAP28/ITGA4/SMARCD3/UBASH3B/MSX2/CYLD/STK4/TRIB3/TCF7L2/PHLDA2/HIPK2/ERCC2/ITGA2/LDOC1/CSNK1E/MMP9/FLOT1/CARM1/PARP9/BCL3/MEF2C/CDK5/WNT5A/TRAF2/NKX3-1/ARF6/CRBN/IFIT2/TXN/ACTB/EIF3E/SUMO3/PLXND1/SP100/FKBP1A/TRIM6/GATA3/PRKCD/CRMP1/PPP3CA/ABL1/NUCKS1/MITD1/PPARG/ID3/TICAM1/CCPG1/MEPCE/IGF1/AKTIP/DVL1/SRI/ZNF675	69
BP	GO:1904019	epithelial cell apoptotic process	27/2306	111/18670	0.0003685	0.007825	0.006021	BID/ICAM1/TNFAIP3/IL6/CCL2/PPARGC1A/CFLAR/CD248/CD40/SORT1/BMPR2/ITGA4/THBS1/ZFP36/STK4/TCF7L2/E2F2/CAST/ARF6/BCL2L1/GSN/TNF/GATA3/HLA-G/SERPINE1/ABL1/GAS6	27
BP	GO:0072073	kidney epithelium development	32/2306	140/18670	0.0003741	0.007917	0.006091	BMP2/LIF/AHI1/BASP1/FGF2/SIX1/STAT1/KLHL3/VEGFA/LZTS2/BMP4/WWTR1/SLIT2/IRX3/PKD2/HOXA11/ACAT1/MYO1E/BMPER/PODXL/SPRY1/YAP1/SIX4/MEF2C/HES5/PGF/TACSTD2/GATA3/HOXB7/SDC4/LGR4/OSR1	32
BP	GO:0061333	renal tubule morphogenesis	21/2306	78/18670	0.0003773	0.007917	0.006091	BMP2/AHI1/FGF2/SIX1/KLHL3/VEGFA/LZTS2/BMP4/IRX3/PKD2/HOXA11/SIX4/MEF2C/HES5/PGF/TACSTD2/GATA3/COL4A1/HOXB7/LGR4/OSR1	21
BP	GO:0030656	regulation of vitamin metabolic process	7/2306	13/18670	0.0003779	0.007917	0.006091	IL1B/NFKB1/RDH10/CYP27B1/SNAI2/VDR/TNF	7
BP	GO:0051451	myoblast migration	7/2306	13/18670	0.0003779	0.007917	0.006091	SIX1/ROCK1/NET1/PLEKHO1/SIX4/AKIRIN1/BIN3	7
BP	GO:0001890	placenta development	34/2306	152/18670	0.0003829	0.007994	0.006151	PTGS2/CSF2/LIF/PLCD3/NDP/CEBPB/BIRC2/PLCD1/EPAS1/SOCS3/RXRA/NR2F2/BMPR2/PKD2/ADA/STK4/CYP27B1/PHLDA2/ITGB8/LDOC1/GJB2/ASCL2/VDR/JUNB/CDKN1C/RBM15/BIRC6/DLX3/CEBPA/KRT19/ARID1A/PRDM1/PPARG/BPTF	34
BP	GO:0043687	post-translational protein modification	67/2306	361/18670	0.000397	0.00826	0.006355	IL6/PSME2/PSMA6/PSMB10/CSF1/PSMB8/TMEM132A/PSMB7/LMO7/PSME1/EPAS1/C3/KLHL3/MXRA8/ASB8/BMP4/RAB13/LAMB1/PSMB9/AFP/SOCS3/RAB38/VCAN/NUB1/PSMA3/DDA1/KTN1/UBE2M/KLHL5/SDC2/CAND1/DNAJC3/DDB2/CCDC8/ASB1/PSMA1/KBTBD6/DCAF16/SPSB1/PSMB2/ASB5/FEM1C/ATG7/RABGGTA/RAB3A/COPS4/PSMB3/TNC/FBN1/FBXW4/FBXL22/KLHL20/UBD/RBBP5/SOCS2/KCTD6/KLHL13/PSMA8/FBXO17/GAS6/ASB2/PRSS23/PSME4/FBXL5/PSMB5/SERPINA1/PSMF1	67
BP	GO:0007265	Ras protein signal transduction	80/2306	448/18670	0.0004076	0.008453	0.006503	CYTH3/PLD1/RAB23/ABCA1/CSF1/NTN1/SQSTM1/FGF2/PDPN/PSD4/PLCE1/RAB9A/AUTS2/ROCK1/ARHGEF10/PLK2/RAB13/PDGFRB/RERG/CDC42EP1/RAB38/CDC42EP3/RHOJ/IQSEC1/NET1/RAB33A/RAB2B/RDX/STMN3/GPSM2/RAB40B/F2R/RHOB/TGFB2/FGD4/NISCH/SPRY1/LPAR1/GNA13/RAB4A/RHOBTB3/FGD1/GNA12/FLOT1/RHOU/ROBO1/ARHGAP1/RAB32/RAB3A/ARF6/RAB18/ARHGEF5/EPS8/DGKI/TIAM2/ARHGEF17/RAB9B/ARHGEF12/GDI1/MAPRE2/PLEKHG4/ABL1/COL1A2/ROCK2/RALA/ARHGDIB/KSR1/CDKN1A/FARP1/FGF10/RASSF1/CDC42/IGF1/SHOC2/RAB31/NGEF/PLEKHG2/CRKL/ADRA2A/WASF2	80
BP	GO:0044106	cellular amine metabolic process	30/2306	129/18670	0.0004117	0.00849	0.006532	PSME2/PSMA6/PSMB10/PSMB8/KYNU/SAT1/PSMB7/PSME1/IDO1/SLC7A11/PSMB9/PNKD/PSMA3/SMOX/HNMT/PRG3/MOXD1/AADAT/PSMA1/PSMB2/ABCC2/VPS35/ALDH7A1/PSMB3/ABAT/PSMA8/PSME4/PSMB5/DHPS/PSMF1	30
BP	GO:0051047	positive regulation of secretion	77/2306	428/18670	0.0004121	0.00849	0.006532	IL6/IL1B/RIPK2/IL33/KCNN4/ADORA2A/IL1A/IFIH1/IFNGR1/C1QTNF1/TNFRSF14/RAB9A/PANX1/GIP/HLA-E/MYB/IL4R/HLA-F/CD58/DDX58/IL26/PANX2/CCL3/SNX4/CYBA/OXTR/IL17RB/GLUD1/EDN1/RAB2B/AKAP12/GSDMD/TCF7L2/RAB3GAP1/MBP/INHBB/MYOM1/SDCBP/F2R/CCL1/TGFB2/PPIA/CDK5/WNT5A/ADORA1/KCNB1/NKX3-1/VPS35/MYO18A/RAB3A/ARF6/SYT4/ARF1/ABAT/HAVCR2/TNF/SYTL4/DYNLL1/STXBP5/STXBP1/TRIM6/GATA3/SYT1/SDC4/ABL1/VAMP7/PTPN11/NPPA/FERMT1/ATP13A2/IGF1/MYH10/SRI/P2RX7/ADAM8/PDCD6IP/CYP19A1	77
BP	GO:0015711	organic anion transport	85/2306	482/18670	0.0004139	0.008498	0.006538	SLC25A24/IL1B/SLC7A2/KCNN4/BDKRB2/SLC43A2/OSBPL10/ADORA2A/ABCA1/PITPNC1/SLC16A6/NFKBIE/ATP8B1/PDPN/SLC2A6/SLC27A3/GLS/SLC2A1/SLC7A11/PLA2G4A/AQP9/SLC38A2/PLIN2/ACACB/PPFIA1/CA12/FABP3/RXRA/NFE2L1/ARL6IP5/SLC16A5/THBS1/CROT/SLC3A2/EDN1/SLCO4A1/CYB5R2/RAB3GAP1/SLC35A1/CPT1A/ACACA/RGS2/ABCC1/PLEKHA3/LRRC8E/ABCD1/PLA2G12A/RGS4/ABCC2/ADORA1/TNFAIP8L3/RAB3A/SYT4/OSBPL5/ABAT/SLC38A4/SLC25A20/CLN8/ATP8A2/STXBP1/PRKAB2/PRKCD/GRM2/SYT1/SLC38A6/HBB/SLC26A3/SCP2/PPARG/SLC19A1/SLC35B4/SLC35B1/NMUR2/OSR1/P2RX7/SLC37A1/PPFIA3/SLC38A1/TMEM30B/MID1IP1/CA5B/SLC16A9/SFXN4/STARD7/ABCC11	85
BP	GO:0110020	regulation of actomyosin structure organization	24/2306	95/18670	0.0004219	0.008634	0.006643	ASAP3/ROCK1/ARHGEF10/PAK1/PPFIA1/ARHGAP28/EDN1/PXN/LPAR1/FHOD1/MEF2C/PHLDB2/PFN2/ARHGEF5/SH3PXD2B/TACSTD2/MIR1-2/SDC4/ABL1/ROCK2/EPHA1/CDC42/SERPINF2/WASF2	24
BP	GO:0051402	neuron apoptotic process	48/2306	239/18670	0.0004263	0.008695	0.00669	SOD2/BID/ITGA1/CCL2/ADORA2A/PPARGC1A/CEBPB/SIX1/ROCK1/MYB/SET/LANCL1/FYN/BACE1/CCL3/NRBP2/FADD/PPT1/UBE2M/HIPK2/F2R/TGFB2/CLCF1/GDF5/SIX4/POLB/AXL/MEF2C/CDK5/KCNB1/BHLHB9/BCL2L1/TP63/BTG2/TRIM2/TNF/HYOU1/MIR125B1/STXBP1/GATA3/USP53/ADARB1/OXR1/EN2/MAX/SIGMAR1/FAM162A/ADAM8	48
BP	GO:0060491	regulation of cell projection assembly	38/2306	177/18670	0.0004289	0.008718	0.006708	ICAM1/PLD1/FSCN1/KIT/ATP8B1/FNBP1L/CORO1C/AUTS2/CDC42EP1/CDC42EP3/SLIT2/CCDC88A/CYLD/DYNC2LI1/RDX/DPYSL3/PODXL/TCHP/AKIRIN1/ARPC2/EVI5L/ARF6/PFN2/EPS8/BIN3/DYNLL1/TACSTD2/PLEK2/PRKCD/MARK4/MIR214/MYO10/RALA/MNS1/CDC42/SH3YL1/P2RX7/WASF2	38
BP	GO:0045732	positive regulation of protein catabolic process	44/2306	214/18670	0.0004304	0.008721	0.00671	TNFAIP3/IL1B/IL33/TRIB1/TRIB2/BAG2/DAB2/TNFRSF1B/FOXO1/PLK2/NKD2/ANKIB1/HERPUD1/NUB1/DDA1/ITCH/RNF14/TRIB3/RDX/ARIH2/HECW2/CSNK1E/SH3D19/ARIH1/ASB5/WNT5A/ATG7/VPS35/RNF144B/RGN/RAD23A/TNF/CEBPA/DET1/MAGEF1/SH3RF2/FBXL5/DVL1/MYLIP/NEDD4/ADAM8/ZFAND2A/OSBPL7/ADRA2A	44
BP	GO:0071236	cellular response to antibiotic	33/2306	147/18670	0.0004323	0.00873	0.006717	ZC3H12A/TNFAIP3/IL6/GPR37L1/CCL7/DAXX/FOXO1/AHR/PLA2G4A/KLF2/MYB/PPIF/ETS1/KLF4/NET1/MAPK13/PDGFD/SIRPA/ADCY7/RHOB/TP53INP1/ADCY3/STAT6/AXL/ITPR2/MEF2C/SIRT1/TXN/PRKCD/ABL1/ACTR2/SIGMAR1/ID3	33
BP	GO:0051017	actin filament bundle assembly	34/2306	153/18670	0.0004349	0.008755	0.006736	PLS3/FSCN1/ASAP3/ROCK1/ARHGEF10/PAK1/PPFIA1/LIMA1/NEDD9/ITGB5/ARHGAP28/FMN2/RDX/PXN/DPYSL3/RHOB/LPAR1/FHOD1/PHLDB2/PFN2/ARHGEF5/EPS8/SH3PXD2B/TACSTD2/ACTN4/SDC4/ZYX/ABL1/ROCK2/PDXP/EPHA1/CDC42/SERPINF2/WASF2	34
BP	GO:0045429	positive regulation of nitric oxide biosynthetic process	14/2306	43/18670	0.0004398	0.008824	0.006789	ICAM1/PTGS2/IL1B/DDAH1/KLF2/PKD2/KLF4/EDN1/TNF/ASS1/DDAH2/PTX3/HBB/TICAM1	14
BP	GO:0071260	cellular response to mechanical stimulus	21/2306	79/18670	0.000455	0.009099	0.007001	PTGS2/IL1B/NFKB1/IRF1/SLC2A1/SLC38A2/CNN2/COL1A1/CD40/FAS/FADD/CYBA/MAP3K1/ITGA2/MAP3K2/TNFRSF10B/TLR3/BCL10/PTPN11/ENG/NPPA	21
BP	GO:0006694	steroid biosynthetic process	41/2306	196/18670	0.0004595	0.00916	0.007047	BMP2/AKR1B1/CH25H/IL1B/NFKB1/PPARGC1A/HSD11B1/ACOX2/INSIG2/OSBPL1A/ACACB/RDH8/SCD/DDX20/DHRS11/SRD5A1/CYP27B1/CYB5R2/TM7SF2/ACAT2/ACACA/AMACR/NPC1L1/SNAI2/VDR/SIRT1/OSBPL3/HSD17B12/ACAA2/HSD3B7/TNF/ACBD3/HSD17B7/GPAM/HSD17B6/STARD3NL/ACOT8/SCP2/IDI1/CYP19A1/OSBPL7	41
BP	GO:1905331	negative regulation of morphogenesis of an epithelium	8/2306	17/18670	0.0004621	0.009183	0.007065	STAT1/BMP4/PHLDB2/WNT5A/SULF1/TNF/TACSTD2/GATA3	8
BP	GO:0090257	regulation of muscle system process	51/2306	259/18670	0.0004674	0.009257	0.007122	ZC3H12A/PTGS2/PPARGC1A/KIT/PRKCA/JARID2/PLCE1/TNFRSF1B/FOXO1/IL6ST/ROCK1/PAK1/GSTO1/CALM1/PDE4D/CAMK2D/KLF4/LMNA/LMCD1/MYL5/OXTR/ADA/EDN1/DMPK/F2R/RGS2/ITGA2/ERRFI1/HCN4/MIR19B2/RGS4/ADORA1/ABAT/CAMK2G/CALM2/ATP2A2/MIR1-2/DOCK4/PPP3CA/ROCK2/MIR214/PDE4B/NPPA/NMUR2/PDE5A/MIR199A2/IGF1/SRI/CASQ1/KCNB2/ADRA2A	51
BP	GO:0150011	regulation of neuron projection arborization	6/2306	10/18670	0.0004752	0.009382	0.007218	MOV10/WNT5A/FZD4/DLG4/DVL1/DVL2	6
BP	GO:0042110	T cell activation	82/2306	464/18670	0.0004846	0.009538	0.007338	NFKBIZ/ZC3H12A/ICAM1/CCL5/IL6/CD70/VCAM1/MAP3K8/IL1B/RELB/CD83/RIPK2/CCL2/SH3RF1/ADORA2A/CDK6/PSMB10/IRF1/TNFSF9/KIT/CEBPB/PIK3CD/IL7R/MAFB/TNFRSF14/RSAD2/PDCD1LG2/PRR7/TNFRSF1B/BTN3A1/IDO1/IL6ST/BMP4/TNFSF13B/PAK1/HLA-E/IL12A/IL18R1/MYB/IL4R/SOCS1/CD44/FYN/LRRC32/FADD/IL15/CYLD/ADA/EIF2AK4/ZFP36L2/MAD1L1/SIRPA/EBI3/RPL22/STAT6/DUSP3/EFNB1/BCL3/FZD8/MICB/GSN/HAVCR2/FKBP1A/GATA3/HLA-G/PPP3CA/SDC4/PRDM1/ABL1/BCL10/DUSP10/PTPN11/CDC42/MYH9/PDE5A/IGF1/STAT3/P2RX7/SASH3/FZD7/ADAM8/CBFB	82
BP	GO:0010922	positive regulation of phosphatase activity	12/2306	34/18670	0.0004875	0.009565	0.007359	BMP2/ITGA1/PPP1R15A/PDGFRB/CALM1/PPP1R12A/SLC39A10/ITGA2/MEF2C/RGN/CALM2/CHP2	12
BP	GO:0043200	response to amino acid	27/2306	113/18670	0.0004988	0.009755	0.007505	ICAM1/PPARGC1A/CEBPB/SIX1/SESN1/GIP/SOCS1/COL1A1/FYN/CYBA/EDN1/COL5A2/SH3BP4/PDGFD/SESN3/UBR1/BCL2L1/SESN2/TNF/ASS1/ASNS/PDGFC/COL16A1/COL4A1/CPS1/COL1A2/CAPN2	27
BP	GO:0050900	leukocyte migration	87/2306	499/18670	0.0005189	0.01012	0.007783	CXCL1/CXCL2/CXCL6/CCL20/ICAM1/BDKRB1/CCL5/OLR1/IL6/CH25H/CXCL5/MMP1/VCAM1/IL1B/ITGA1/CXCL10/IL33/CCL2/CCL8/CSF1/CCL7/KIT/PIK3CD/TNFRSF14/PF4V1/SLC7A11/VEGFA/ROCK1/IRAK4/JAM3/IL12A/CCL3L3/CXCL3/COL1A1/CMKLR1/JAM2/CD44/CD58/FYN/SLIT2/PDE4D/CXCL11/CCL3/GRB14/FADD/ITGA4/THBS1/SLC12A2/SLC3A2/PIK3R2/ADA/EDN1/CXCL9/PDGFD/SIRPA/CCL1/TGFB2/SDC2/ITGA2/PPIA/PPIL2/GYPB/AKIRIN1/WNT5A/ADORA1/ARHGEF5/EPS8/HSD3B7/TNF/PGF/SLAMF8/CEACAM3/TNFRSF10B/GCNT1/CNR2/GATA3/SDC4/SERPINE1/COL1A2/PDE4B/GAS6/PTPN11/MYH9/ITGA6/ADAM8/CYP19A1/CRKL	87
BP	GO:0044262	cellular carbohydrate metabolic process	55/2306	286/18670	0.000526	0.01022	0.007865	AKR1B1/GK/PPARGC1A/C1QTNF1/PYGL/FOXO1/SLC2A1/IL6ST/MYOF/HK2/PPP1R3F/ACACB/COX11/UGP2/NAGK/CALM1/IRS1/NFE2L1/IDH1/PGM2L1/DYRK2/GNPTAB/GLB1/PHLDA2/ENPP1/PMAIP1/KAT2B/IMPA2/PHKB/CSGALNACT1/HAS2/CSGALNACT2/ITPKA/SIRT1/COQ3/RGN/SESN2/HAS1/GYG1/HAS3/DUSP12/INPP5B/GYS2/EXT1/HS2ST1/PDK3/ENOSF1/SLC35B4/PHKA2/SIK1/INPP1/IGF1/GNMT/STAT3/SIRT6	55
BP	GO:0002367	cytokine production involved in immune response	25/2306	102/18670	0.000529	0.01025	0.007885	IL6/IL1B/KIT/TNFRSF14/RSAD2/TNFRSF1B/HLA-E/IL12A/IL18R1/HLA-F/IRAK3/DDX58/TGFB2/SIRT1/WNT5A/TRAF2/TNF/TLR3/TRIM6/GATA3/HLA-G/BCL10/GAS6/TICAM1/SASH3	25
BP	GO:0055002	striated muscle cell development	37/2306	173/18670	0.0005468	0.01056	0.008125	FLNC/SIX1/MYOF/VEGFA/CFLAR/BMP4/PAK1/PDGFRB/LMNA/ACTC1/EDN1/MYOM1/SGCD/RGS2/SMYD3/SIX4/MEF2C/MIR19B2/RGS4/MYOM3/BIN3/PDLIM5/CHRNB1/MIR1-2/KRT19/PPP3CA/TMOD2/MYH6/NPPA/MIR199A2/IGF1/MYH10/ACTG1/CASQ1/SGCB/DNER/TBX3	37
BP	GO:0051146	striated muscle cell differentiation	56/2306	293/18670	0.0005506	0.0106	0.008155	BMP2/CXCL10/FLNC/SIX1/MYOF/VEGFA/CFLAR/BMP4/PAK1/POPDC2/PDGFRB/IL4R/RXRA/SORT1/LMNA/ACTC1/EDN1/CXCL9/DMPK/MYOM1/SGCD/RGS2/SMYD3/GATA6/MORF4L2/FLOT1/EHD1/PLEKHO1/SIX4/MEF2C/MIR19B2/RGS4/GDF15/MYOM3/BIN3/PDLIM5/CHRNB1/MIR1-2/KRT19/ARID1A/PPP3CA/TMOD2/MYH6/NPPA/SIK1/MYH9/MIR199A2/IGF1/MYH10/ACTG1/CASQ1/FZD7/SGCB/DNER/CAPN2/TBX3	56
BP	GO:0051188	cofactor biosynthetic process	61/2306	326/18670	0.0005681	0.01082	0.008324	NAMPT/PTGS2/SLC11A2/PPARGC1A/SLC2A6/KYNU/IDO1/SLC7A11/MAT2A/HK2/ACACB/ELOVL5/ENO2/ADPGK/FYN/COQ10B/NUP133/NFE2L1/SCD/ELOVL7/PGM2L1/CYBA/GCH1/ACAT1/NNMT/PPT1/PNPO/ACACA/PSAT1/ACSL5/CYP1A2/CBR4/PDSS2/CHAC2/ELOVL2/UBIAD1/PARP9/HAGH/COQ3/PPCS/RGN/HSD17B12/PDHB/ALAS1/SLC25A39/BDH2/PGAM4/PDK3/CNDP2/SUCLA2/NUP35/MGST2/MMADHC/IGF1/STAT3/ALDOC/PTS/P2RX7/SIRT6/SLC25A16/ELOVL3	61
BP	GO:0006195	purine nucleotide catabolic process	14/2306	44/18670	0.0005725	0.01082	0.008324	PDE4D/PDE1A/AMPD3/NUDT18/NUDT7/ADA/ACAT1/NT5C2/NUDT11/NUDT1/ABCD1/PDE4B/PDE5A/HINT1	14
BP	GO:0046688	response to copper ion	14/2306	44/18670	0.0005725	0.01082	0.008324	ICAM1/MT1G/MT1M/MT1E/MT1A/MT1X/MT2A/MT1H/MT1F/IL1A/DAXX/NFE2L1/BACE1/CYP1A2	14
BP	GO:0060412	ventricular septum morphogenesis	14/2306	44/18670	0.0005725	0.01082	0.008324	ID2/CITED2/BMP4/FZD1/SLIT2/BMPR2/FGFRL1/FZD2/TGFB2/ROBO1/WNT5A/MIR1-2/RBM15/TBX3	14
BP	GO:0070266	necroptotic process	14/2306	44/18670	0.0005725	0.01082	0.008324	BIRC3/BIRC2/PYGL/CFLAR/PPIF/FAS/FADD/CYLD/TNF/MLKL/TLR3/RBCK1/MIR214/TICAM1	14
BP	GO:1904407	positive regulation of nitric oxide metabolic process	14/2306	44/18670	0.0005725	0.01082	0.008324	ICAM1/PTGS2/IL1B/DDAH1/KLF2/PKD2/KLF4/EDN1/TNF/ASS1/DDAH2/PTX3/HBB/TICAM1	14
BP	GO:0042035	regulation of cytokine biosynthetic process	27/2306	114/18670	0.000578	0.01089	0.008378	IL6/IL1B/NFKB1/HSPB1/IRF1/TRIB2/IL1A/CEBPB/EREG/KLF4/THBS1/ZFP36/AKAP12/INHBB/PRG3/EBI3/ERRFI1/ASB1/BCL3/WNT5A/TNF/TLR3/GATA3/BCL10/ZNF287/TICAM1/STAT3	27
BP	GO:0002720	positive regulation of cytokine production involved in immune response	16/2306	54/18670	0.000582	0.01091	0.008396	IL6/IL1B/TNFRSF14/RSAD2/HLA-E/IL18R1/HLA-F/DDX58/WNT5A/TRAF2/TRIM6/GATA3/HLA-G/BCL10/TICAM1/SASH3	16
BP	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	40/2306	192/18670	0.0005827	0.01091	0.008396	ICAM1/CCL5/IL6/CSF2/LIF/RIPK2/EHD4/PARP14/KIT/TNFRSF14/IL6ST/VEGFA/EREG/IL12A/SOCS3/CD44/CD40/FYN/NEDD9/IL15/TGFA/HBEGF/GHR/SEMA4D/CLCF1/PARP9/MIR19B2/ADORA1/HES5/TNF/DLG4/ABL1/GAS6/PTPN11/FGF10/IGF1/STAT3/ARL2BP/DVL2/ADRA2A	40
BP	GO:0097300	programmed necrotic cell death	15/2306	49/18670	0.0005847	0.01092	0.008398	BIRC3/BIRC2/PYGL/CFLAR/PPIF/FAS/FADD/CYLD/TRAF2/TNF/MLKL/TLR3/RBCK1/MIR214/TICAM1	15
BP	GO:0036294	cellular response to decreased oxygen levels	44/2306	217/18670	0.0005864	0.01092	0.008398	ICAM1/NAMPT/PTGS2/PSME2/PSMA6/PSMB10/PPARGC1A/CITED2/DDAH1/PSMB8/PSMB7/PSME1/EPAS1/VEGFA/EEF2K/CFLAR/TBL2/PSMB9/PSMA3/LMNA/FMN2/EDN1/EGLN1/PMAIP1/HIPK2/GATA6/PSMA1/PSMB2/SIRT1/NKX3-1/PSMB3/ACAA2/HYOU1/PSMA8/PDK3/ROCK2/MIR214/UBB/PSME4/FAM162A/PSMB5/CLCA1/ADAM8/PSMF1	44
BP	GO:0030308	negative regulation of cell growth	39/2306	186/18670	0.0005941	0.01103	0.008483	BDKRB1/OSGIN2/NTN1/FHL1/PAK1/RERG/NDRG3/SLIT2/BMPR2/CYP27B1/CRYAB/PPT1/SH3BP4/ENPP1/SEMA4D/DCBLD2/PPP1R9B/TGFB2/RGS2/TCHP/ADIPOR2/SMARCA2/SERTAD2/IFRD1/CDKN2C/DACT3/CDK5/SIRT1/WNT5A/RGS4/SESN2/RTN4/PPARG/CDKN1A/NPPA/SEMA4F/MIR199A2/TSPYL2/ST20	39
BP	GO:0007260	tyrosine phosphorylation of STAT protein	22/2306	86/18670	0.0005989	0.01105	0.0085	CCL5/IL6/CSF2/LIF/PARP14/KIT/IL6ST/IL12A/SOCS1/SOCS3/CD40/FYN/IL15/GHR/CLCF1/PARP9/MIR19B2/HES5/TNF/IGF1/STAT3/ARL2BP	22
BP	GO:0070542	response to fatty acid	22/2306	86/18670	0.0005989	0.01105	0.0085	ZC3H12A/PTGS2/PID1/CLDN1/PPARGC1A/INSIG2/PTGFR/FABP3/IRS1/SCD/EDN1/PTGER2/CPT1A/ACACA/AKAP8/TNC/ASS1/CPS1/PDK3/PPARG/ID3/GNG2	22
BP	GO:0072329	monocarboxylic acid catabolic process	30/2306	132/18670	0.0006203	0.01141	0.008778	LPIN1/ACOX2/ACACB/AIG1/HIBCH/IRS1/NUDT7/CROT/FAH/ACAT1/HADH/ACAT2/CPT1A/AMACR/ABCD1/CRYL1/SESN2/ACAA2/DECR2/ABAT/ALDH5A1/ABHD3/LONP2/BDH2/LDHD/ACOT8/PECR/SCP2/ACOXL/ACADM	30
BP	GO:0001667	ameboidal-type cell migration	81/2306	461/18670	0.0006258	0.01147	0.008823	ZC3H12A/PTGS2/HSPB1/KIT/FGF2/PRKCA/ARID5B/MCC/CORO1C/VEGFA/PLK2/BMP4/RAB13/PAK1/CD40/SLIT2/RHOJ/IQSEC1/ETS1/NR2F2/BMPR2/EPB41L4B/KLF4/ITGA4/THBS1/EDN1/KRT16/BMPER/AKAP12/PXN/CARD10/HBEGF/SEMA4D/RHOB/PIK3R3/TGFB2/ITGA2/HAS2/STARD13/CYGB/MMP9/GNA12/EFNB1/MEOX2/AMOTL1/ROBO1/MEF2C/SIRT1/MIR19B2/WNT5A/ARF6/KRT2/PFN2/MIR137/APPL2/SPARC/TACSTD2/HAS1/PTPRM/PLXND1/SP100/GATA3/RTN4/SDC4/MAPRE2/ABL1/ROCK2/LGALS8/DUSP10/ARHGDIB/PPARG/PTPN11/FGF10/PKN2/FERMT1/MYH9/SEMA4F/MIR199A2/GLIPR2/ATOH8/WASF2	81
BP	GO:0009308	amine metabolic process	31/2306	138/18670	0.0006272	0.01147	0.008823	VCAM1/PSME2/PSMA6/PSMB10/PSMB8/KYNU/SAT1/PSMB7/PSME1/IDO1/SLC7A11/PSMB9/PNKD/PSMA3/SMOX/HNMT/PRG3/MOXD1/AADAT/PSMA1/PSMB2/ABCC2/VPS35/ALDH7A1/PSMB3/ABAT/PSMA8/PSME4/PSMB5/DHPS/PSMF1	31
BP	GO:0050673	epithelial cell proliferation	77/2306	434/18670	0.0006297	0.01148	0.008832	BMP2/TNFAIP3/CCL5/CCL2/ID2/ERN1/CDK6/KIT/CEBPB/FGF2/PRKCA/SIX1/MCC/STAT1/VEGFA/EREG/CFLAR/BMP4/LAMB1/BCL2L2/NR2F2/BMPR2/CCND1/IL26/LIMS2/ITGA4/CYBA/THBS1/ZFP36/SULF2/BMPER/TCF7L2/TGFA/TGFB2/ERRFI1/SNAI2/YAP1/HAS2/GDF5/STAT6/SIX4/ROBO1/MEF2C/NOX5/VDR/SIRT1/WNT5A/NKX3-1/SULF1/RGN/KRT2/TP63/HES5/CDKN1C/TNF/PGF/SPARC/TACSTD2/OSR2/SERPINB1/PTPRM/GATA3/RTN4/LGR4/DUSP10/PPARG/FGF10/BTBD10/FERMT1/IGF1/AGGF1/STAT3/OSR1/FZD7/SIRT6/ATOH8/NFIB	77
BP	GO:0061013	regulation of mRNA catabolic process	41/2306	199/18670	0.0006344	0.01153	0.008872	ZC3H12A/PSME2/PSMA6/HSPB1/PSMB10/PSMB8/PRKCA/PSMB7/PSME1/ROCK1/PSMB9/SET/MOV10/FTO/PSMA3/ZFP36/EXOSC6/ZFP36L2/CSDC2/HNRNPA0/PDE12/DCP1A/PSMA1/PSMB2/PABPC1/BTG2/SERBP1/SAMD4B/PSMB3/CNOT8/SYNCRIP/PRKCD/PSMA8/FASTKD3/ROCK2/FXR2/UBB/ANGEL2/PSME4/PSMB5/PSMF1	41
BP	GO:0034109	homotypic cell-cell adhesion	21/2306	81/18670	0.0006528	0.01183	0.009102	CCL5/HSPB1/C1QTNF1/PRKCA/PDPN/SLC7A11/VCL/ANK3/UBASH3B/RDX/ABAT/ACTB/STXBP1/PEAR1/PRKCD/HBB/GAS6/MYH9/ACTG1/TLN1/MYL12A	21
BP	GO:0045070	positive regulation of viral genome replication	12/2306	35/18670	0.0006593	0.01191	0.009166	CCL5/IFIT1/ADAR/PPIA/PDE12/PABPC1/RAD23A/STAU1/ADARB1/NUCKS1/PKN2/TRIM38	12
BP	GO:0042176	regulation of protein catabolic process	69/2306	381/18670	0.0006641	0.01197	0.009206	TNFAIP3/PSME2/IL1B/IL33/TRIB1/TRIB2/BAG2/DAB2/PSME1/TNFRSF1B/FOXO1/ROCK1/PLK2/NKD2/RAD23B/ANKIB1/IRAK3/FYN/HERPUD1/NFE2L1/NUB1/DDA1/ITCH/RNF14/FMN2/TRIB3/RDX/ARNTL/SDCBP/HIPK2/ARIH2/MAP1A/HECW2/CSNK1E/GNA12/SH3D19/ARIH1/ASB5/WNT5A/ATG7/ARAF/VPS35/RNF144B/RGN/TIMP4/RAD23A/UBXN1/TNF/USP14/BRSK2/CEBPA/DET1/WDR91/MAGEF1/UBB/SH3RF2/FBXL5/ATP13A2/DVL1/MYCBP2/MYLIP/NEDD4/ADAM8/ZFAND2A/SF3B3/OSBPL7/PSMF1/ADRA2A/SNX3	69
BP	GO:0046660	female sex differentiation	27/2306	115/18670	0.0006679	0.012	0.009232	ICAM1/KIT/CEBPB/ARID5B/VEGFA/EREG/AFP/SLIT2/IDH1/LHX8/SRD5A1/INHBB/LHFPL2/AXL/SIRT1/WNT5A/BCL2L1/TP63/FZD4/EIF2B5/EIF2B4/PTX3/ZNF830/UBB/FGF10/CYP19A1/TBX3	27
BP	GO:0060537	muscle tissue development	73/2306	408/18670	0.0006734	0.01206	0.009279	BMP2/MAFF/ID2/MSC/PPARGC1A/PITX1/FGF2/MEIS1/JARID2/SIX1/VEGFA/CFLAR/BMP4/PAK1/POPDC2/PDGFRB/RXRA/SAP30/NR2F2/PKD2/LMNA/PIM1/ACTC1/EDN1/MYOM1/ARNTL/SGCD/TGFB2/RGS2/SRPK3/GATA6/YAP1/HOXD9/FLNB/FLOT1/MEOX2/IFRD1/SIX4/MEF2C/AKIRIN1/CDK5/MIR19B2/WNT5A/RGS4/BTG2/MYOM3/MYLK/DDX5/BIN3/PDLIM5/SGCG/MIR1-2/FKBP1A/ARID1A/PPP3CA/ASB2/MYH6/ENG/NPPA/SIK1/UBE4B/MIR199A2/IGF1/MYH10/OSR1/CASQ1/FZD7/SGCB/EYA2/DNER/SIRT6/VAMP5/TBX3	73
BP	GO:0031098	stress-activated protein kinase signaling cascade	59/2306	315/18670	0.0006752	0.01206	0.009279	BMP2/AKR1B1/ZC3H12A/IRAK2/MAP3K8/IL1B/RIPK2/NFKB1/SH3RF1/TRIB1/ERN1/TPD52L1/DAXX/FOXO1/ANKRD6/VEGFA/DNAJA1/IRAK4/MID1/PAK1/FAS/ARL6IP5/IL26/ITCH/ZFP36/CYLD/MAP3K1/STK4/EDN1/PRMT1/MAPK13/CRYAB/SDCBP/HIPK2/SIRPA/TGFB2/DUSP3/GADD45G/FZD8/WNT5A/TRAF2/ARHGEF5/TNF/MAP3K2/MLKL/FZD4/TLR3/DUSP10/UBB/PER1/PJA2/SH3RF2/GDF6/DVL2/SERPINF2/TAOK1/FZD7/CRKL/ZNF675	59
BP	GO:0002478	antigen processing and presentation of exogenous peptide antigen	37/2306	175/18670	0.0006871	0.01224	0.009414	PSME2/TAP1/TAP2/PSMA6/PSMB10/PSMB8/PSMB7/PSME1/OSBPL1A/CTSS/HLA-E/PSMB9/HLA-F/ITGB5/PSMA3/CYBA/HLA-A/CLTC/DCTN1/PSMA1/PSMB2/CAPZA2/KIF4B/ARF1/PSMB3/DYNLL1/ACTR10/PSMA8/HLA-G/HLA-DQB1/TAPBP/PSME4/PSMB5/DCTN3/HLA-B/HLA-H/PSMF1	37
BP	GO:0001649	osteoblast differentiation	45/2306	225/18670	0.0006943	0.01233	0.009486	BMP2/IL6/ID2/CDK6/CEBPD/CEBPB/IFITM1/IL6ST/TP53INP2/BMP4/WWTR1/FZD1/COL1A1/BMPR2/VCAN/CCL3/ADAR/MSX2/PTHLH/CLTC/SEMA4D/TMEM64/SNAI2/LRP5/TPM4/MEF2C/JUNB/ITGA11/TP63/RANBP3L/TNC/DDX5/TNF/BGLAP/SH3PXD2B/RSPO2/CEBPA/SYNCRIP/LGR4/ASF1A/ID3/IGF1/ZHX3/MYBBP1A/CBFB	45
BP	GO:0002705	positive regulation of leukocyte mediated immunity	30/2306	133/18670	0.000708	0.01253	0.009638	IL6/IL1B/RSAD2/C3/HLA-E/IL12A/IL18R1/IL4R/HLA-F/CD40/DDX58/SNX4/FADD/HLA-A/EXOSC6/CLCF1/STAT6/TRAF2/MICB/TNF/STXBP1/GATA3/HLA-G/VAMP7/NPPA/TICAM1/P2RX7/HLA-B/SASH3/HLA-H	30
BP	GO:0061572	actin filament bundle organization	34/2306	157/18670	0.000711	0.01253	0.009638	PLS3/FSCN1/ASAP3/ROCK1/ARHGEF10/PAK1/PPFIA1/LIMA1/NEDD9/ITGB5/ARHGAP28/FMN2/RDX/PXN/DPYSL3/RHOB/LPAR1/FHOD1/PHLDB2/PFN2/ARHGEF5/EPS8/SH3PXD2B/TACSTD2/ACTN4/SDC4/ZYX/ABL1/ROCK2/PDXP/EPHA1/CDC42/SERPINF2/WASF2	34
BP	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	13/2306	40/18670	0.0007123	0.01253	0.009638	BDKRB1/CXCL10/GSTO1/CALM1/PKD2/CXCL11/CXCL9/TRPC1/F2R/CALM2/ABL1/SRI/CASQ1	13
BP	GO:0035304	regulation of protein dephosphorylation	31/2306	139/18670	0.0007135	0.01253	0.009638	ITGA1/ENSA/PPP4R4/PPP1R15A/ROCK1/PPP2R1B/PDGFRB/SET/CALM1/PPP1R12A/SLC39A10/DMPK/PPP1R9B/PHACTR2/NUAK1/RCAN1/ADORA1/RGN/TNF/PPP2R5E/CALM2/FKBP1A/PRKCD/ANKLE2/ROCK2/PPP2R5C/PPP1R14C/PPP1R7/SH3RF2/RCAN2/SHOC2	31
BP	GO:0019883	antigen processing and presentation of endogenous antigen	9/2306	22/18670	0.0007224	0.01261	0.009703	TAP1/TAP2/HLA-E/HLA-F/HLA-A/HLA-G/TAPBP/HLA-B/HLA-H	9
BP	GO:0048305	immunoglobulin secretion	9/2306	22/18670	0.0007224	0.01261	0.009703	IL6/IL33/TNFSF13B/HLA-E/POU2F2/CD40/TRAF3IP2/TRAF2/TNF	9
BP	GO:1901655	cellular response to ketone	23/2306	93/18670	0.0007589	0.0132	0.01016	AKR1B1/ICAM1/FOXO1/AHR/CFLAR/KLF2/PTGFR/KLF4/PTGER2/SRD5A1/ACACA/SMYD3/ERRFI1/GJB2/ADCY3/SIRT1/ABCC2/AKAP8/TNC/ASS1/ROCK2/PPARG/GNG2	23
BP	GO:0071456	cellular response to hypoxia	42/2306	207/18670	0.0007603	0.0132	0.01016	ICAM1/PTGS2/PSME2/PSMA6/PSMB10/PPARGC1A/CITED2/DDAH1/PSMB8/PSMB7/PSME1/EPAS1/VEGFA/CFLAR/TBL2/PSMB9/PSMA3/LMNA/FMN2/EDN1/EGLN1/PMAIP1/HIPK2/GATA6/PSMA1/PSMB2/SIRT1/NKX3-1/PSMB3/ACAA2/HYOU1/PSMA8/PDK3/ROCK2/MIR214/UBB/PSME4/FAM162A/PSMB5/CLCA1/ADAM8/PSMF1	42
BP	GO:0045765	regulation of angiogenesis	69/2306	383/18670	0.0007689	0.01331	0.01024	ZC3H12A/TNFAIP3/PTGS2/IL6/IL1B/CXCL10/THBS2/HSPB1/IL1A/RECK/FGF2/DDAH1/PRKCA/C3/STAT1/VEGFA/HK2/ROCK1/PLK2/KLF2/CD40/RHOJ/ETS1/KLF4/HSPG2/THBS1/EGLN1/BMPER/E2F2/CARD10/ADM2/HIPK2/RHOB/TGFB2/ITGB8/GATA6/STARD13/MEOX2/SIRT1/MIR19B2/WNT5A/SULF1/FOXJ2/MIR137/PGF/RNH1/SPARC/MIR1-2/MIR125B1/STIM1/PTPRM/PLXND1/SP100/TLR3/HLA-G/SERPINE1/ABL1/ROCK2/MIR214/PDE3B/HTATIP2/PPARG/EPHA1/ENG/MIR199A2/AGGF1/STAT3/FOXO4/SIRT6	69
BP	GO:0016311	dephosphorylation	83/2306	478/18670	0.0007813	0.01349	0.01038	BMP2/PPP3CC/ITGA1/ENSA/PPP4R4/LPIN1/PTPRE/DUSP6/PPP1R15A/ROCK1/PSPH/PPP2R1B/PDGFRB/SET/DUSP14/CALM1/PPP1R12A/CDC25A/SSH1/SLC39A10/UBASH3B/PTPN13/DUSP23/DMPK/NT5C2/CDC14B/SEMA4D/NT5DC3/PPP1R9B/TGFB2/IMPA2/ITGA2/PHACTR2/PPP4C/CCDC8/NUAK1/RCAN1/DUSP3/POLB/MEF2C/ADORA1/UBLCP1/RGN/TNF/CAMK2G/PPM1D/PPP2R5E/CALM2/PPM1M/PTPRM/FKBP1A/TMEM225/DUSP12/DUSP16/PRKCD/INPP5B/ANKLE2/PPP3CA/DUSP18/CTDSPL2/ROCK2/PPP2R5C/DUSP10/PDXP/CTDSP2/ELL/PPP1R14C/PPP1R7/PTPN11/FARP1/MYH6/DUSP5/INPP1/SH3RF2/RCAN2/SHOC2/LRRC30/MYO1D/SBF1/NT5DC1/EYA2/SDHAF2/CHP2	83
BP	GO:0003299	muscle hypertrophy in response to stress	11/2306	31/18670	0.0007912	0.01351	0.01039	FOXO1/LMNA/GATA6/ERRFI1/MEF2C/ATP2A2/PPP3CA/MIR214/MYH6/NPPA/MIR199A2	11
BP	GO:0009154	purine ribonucleotide catabolic process	11/2306	31/18670	0.0007912	0.01351	0.01039	PDE4D/PDE1A/AMPD3/NUDT18/NUDT7/ACAT1/NUDT11/ABCD1/PDE4B/PDE5A/HINT1	11
BP	GO:0014887	cardiac muscle adaptation	11/2306	31/18670	0.0007912	0.01351	0.01039	FOXO1/LMNA/GATA6/ERRFI1/MEF2C/ATP2A2/PPP3CA/MIR214/MYH6/NPPA/MIR199A2	11
BP	GO:0014898	cardiac muscle hypertrophy in response to stress	11/2306	31/18670	0.0007912	0.01351	0.01039	FOXO1/LMNA/GATA6/ERRFI1/MEF2C/ATP2A2/PPP3CA/MIR214/MYH6/NPPA/MIR199A2	11
BP	GO:0034763	negative regulation of transmembrane transport	29/2306	128/18670	0.0007989	0.0136	0.01046	PID1/IL1B/GSTO1/RRAD/PPIF/CALM1/CAMK2D/ARL6IP5/PKD2/ANK3/THBS1/ENPP1/THADA/RGS2/HECW2/MMP9/GEM/RGS4/CRBN/SLC30A1/TNF/APPL2/CALM2/MIR1-2/OSR1/SRI/NEDD4/SIRT6/ADRA2A	29
BP	GO:2000377	regulation of reactive oxygen species metabolic process	40/2306	195/18670	0.0008022	0.01362	0.01048	ZC3H12A/ICAM1/PTGS2/PID1/IL1B/MMP3/BIRC2/DDAH1/FOXO1/HK2/CFLAR/KLF2/PDGFRB/FYN/PKD2/KLF4/CYBA/GCH1/THBS1/GLA/EDN1/CRYAB/SIRPA/ABCD1/RGN/TNF/PARL/ASS1/DDAH2/PTX3/PRKCD/PDK3/ROCK2/HBB/VDAC1/SLC25A33/CDKN1A/TICAM1/MIR199A2/STAT3	40
BP	GO:0015800	acidic amino acid transport	18/2306	66/18670	0.0008154	0.01381	0.01062	ADORA2A/GLS/SLC7A11/SLC38A2/PPFIA1/ARL6IP5/RAB3GAP1/LRRC8E/ADORA1/RAB3A/SYT4/ABAT/CLN8/STXBP1/GRM2/SYT1/P2RX7/PPFIA3	18
BP	GO:0032868	response to insulin	52/2306	272/18670	0.0008447	0.01422	0.01094	ICAM1/PID1/IL1B/LPIN1/FOXO1/PTPRE/INSIG2/SLC2A1/STAT1/EEF2K/CFLAR/ATP6V1E2/RAB13/PAK1/SOCS1/SOCS3/ATP6V0B/FABP3/SORT1/IRS1/GRB14/TBC1D4/ATP6V0E2/PIK3R2/TRIB3/HADH/SRD5A1/INHBB/ENPP1/PIK3R3/KAT2B/ERRFI1/SESN3/SIRT1/SESN2/BGLAP/APPL2/GCNT1/SOCS2/PRKCD/NUCKS1/PDE3B/MAX/SLC25A33/AP3S1/PPARG/PTPN11/NCOA5/NPPA/RAB31/ATP6V1E1/FOXO4	52
BP	GO:0032481	positive regulation of type I interferon production	20/2306	77/18670	0.0008469	0.01422	0.01094	RIPK2/NFKB1/NFKB2/IRF1/IFIH1/STAT1/IRF7/DDX58/POLR3GL/DHX58/STAT6/FLOT1/POLR3D/TLR3/LRRFIP1/POLR3K/PTPN11/ZBP1/TICAM1/POLR1C	20
BP	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	20/2306	77/18670	0.0008469	0.01422	0.01094	PSME2/PSMA6/PSMB10/CITED2/PSMB8/PSMB7/PSME1/EPAS1/VEGFA/PSMB9/PSMA3/EGLN1/PSMA1/PSMB2/PSMB3/PSMA8/UBB/PSME4/PSMB5/PSMF1	20
BP	GO:0050870	positive regulation of T cell activation	41/2306	202/18670	0.000866	0.0145	0.01116	NFKBIZ/CCL5/IL6/CD70/VCAM1/MAP3K8/IL1B/CD83/RIPK2/CCL2/TNFSF9/IL7R/TNFRSF14/PDCD1LG2/IL6ST/TNFSF13B/PAK1/HLA-E/IL12A/MYB/IL4R/SOCS1/FYN/FADD/IL15/CYLD/ADA/SIRPA/EBI3/EFNB1/HAVCR2/GATA3/HLA-G/BCL10/DUSP10/PTPN11/CDC42/IGF1/SASH3/ADAM8/CBFB	41
BP	GO:0010634	positive regulation of epithelial cell migration	36/2306	171/18670	0.000874	0.01456	0.0112	ZC3H12A/PTGS2/HSPB1/FGF2/PRKCA/VEGFA/PLK2/BMP4/CD40/RHOJ/IQSEC1/ETS1/BMPR2/EPB41L4B/THBS1/EDN1/HBEGF/RHOB/TGFB2/ITGA2/HAS2/MMP9/AMOTL1/SIRT1/WNT5A/ARF6/SPARC/GATA3/RTN4/MAPRE2/ABL1/ROCK2/FGF10/MIR199A2/GLIPR2/ATOH8	36
BP	GO:0043547	positive regulation of GTPase activity	72/2306	405/18670	0.000876	0.01456	0.0112	CCL20/ICAM1/CCL5/TBC1D2/CCL2/CCL8/CCL7/ASAP3/SIPA1L1/CORO1C/ARHGEF10/RIN3/CCL3L3/ARHGAP18/CD40/NEDD9/IQSEC1/NET1/CCL3/TBC1D4/ARHGAP28/RAB3GAP1/RABGAP1/RINL/SEMA4D/F2R/TBC1D22B/CCL1/RAB11FIP2/RGS2/CHN1/ERRFI1/RSU1/RGS16/STARD13/ZC3H15/WNT5A/EVI5L/RGS4/ARHGAP1/RGS7/RGN/RIN2/RANBP3L/FAM13B/ARHGEF5/TIAM2/ARHGAP10/DOCK4/STXBP5/ARHGEF12/RALBP1/PKP4/GDI1/ASAP1/ARHGAP24/ARHGAP21/MAPRE2/PLEKHG4/TBC1D9B/TBC1D19/ARHGDIB/EPHA1/TBC1D10C/RIN1/TBC1D8/ITGA6/DVL2/ANKRD27/CRKL/PICALM/ASAP2	72
BP	GO:0030224	monocyte differentiation	12/2306	36/18670	0.0008789	0.01456	0.0112	MT1G/CSF2/CDK6/CSF1/VEGFA/BMP4/IRF7/ACIN1/MEF2C/MIR125B1/PPARG/MYH9	12
BP	GO:1903131	mononuclear cell differentiation	12/2306	36/18670	0.0008789	0.01456	0.0112	MT1G/CSF2/CDK6/CSF1/VEGFA/BMP4/IRF7/ACIN1/MEF2C/MIR125B1/PPARG/MYH9	12
BP	GO:0048545	response to steroid hormone	69/2306	385/18670	0.0008882	0.01468	0.01129	ICAM1/PTGS2/IL6/CLDN1/PPARGC1A/DAB2/PGRMC2/DAXX/FOXO1/DNAJA1/CFLAR/BMP4/PAK1/COL1A1/RXRA/SLIT2/NR2F2/CCND1/IDH1/CYBA/RNF14/THBS1/FHL2/ZFP36/OXTR/EDN1/PTGER2/LBH/UBR5/SRD5A1/GLB1/ZFP36L2/ARNTL/HNMT/TGFB2/SMYD3/ERRFI1/THRA/GJB2/YAP1/CARM1/VDR/SIRT1/ABCC2/NKX3-1/TP63/DDX5/RNF4/TNF/BGLAP/YWHAH/ASS1/SPARC/KCTD6/GPAM/PAPPA/CPS1/ARID1A/UFSP2/NCOR2/PER1/PPARG/CDKN1A/ENG/CDK7/NEDD4/TADA3/NCOA6/CBFB	69
BP	GO:0006869	lipid transport	66/2306	365/18670	0.0008949	0.01475	0.01135	NFKBIA/IL1B/KCNN4/NFKB1/BDKRB2/OSBPL10/ABCA1/PITPNC1/ATP8B1/C1QTNF1/TEX2/SLC27A3/PLA2G4A/OSBPL1A/AQP9/ESYT1/PLIN2/ACACB/MYB/LIMA1/FABP3/RXRA/UGCG/THBS1/CROT/EDN1/LIPG/CPT1A/ACACA/STOML1/ABCA5/ABCC1/NPC1L1/APOL6/SOAT1/PLEKHA3/ABCD1/PLA2G12A/SIRT1/MIR19B2/OSBPL3/ABCC2/TNFAIP8L3/NKX3-1/OSBPL5/SLC25A20/CLN8/FZD4/ATP8A2/PRKAB2/PRKCD/SCP2/VAMP7/PPARG/PTPN11/SIGMAR1/NMUR2/P2RX7/APOL4/GULP1/TMEM30B/MID1IP1/CYP19A1/OSBPL7/GRAMD1A/STARD7	66
BP	GO:0042089	cytokine biosynthetic process	28/2306	123/18670	0.0009008	0.01481	0.01139	IL6/IL1B/NFKB1/HSPB1/IRF1/TRIB2/IL1A/CEBPB/EREG/IRF7/KLF4/THBS1/ZFP36/AKAP12/INHBB/PRG3/EBI3/ERRFI1/ASB1/BCL3/WNT5A/TNF/TLR3/GATA3/BCL10/ZNF287/TICAM1/STAT3	28
BP	GO:0070646	protein modification by small protein removal	56/2306	299/18670	0.0009118	0.01495	0.0115	NFKBIA/BIRC3/ZC3H12A/TNFAIP3/TNIP1/PSME2/IL33/PSMA6/PSMB10/IFIH1/BIRC2/PSMB8/PSMB7/PSME1/USP12/TNIP3/TRAF3/RAD23B/PSMB9/SENP7/DDX58/PSMA3/CDC25A/ITCH/CYLD/KAT2B/DDB2/USP38/PSMA1/POLB/PSMB2/TRAF2/TRIM21/COPS4/PSMB3/INO80C/RAD23A/ACTB/UBXN1/USP14/BAP1/GATA3/USP53/PSMA8/USP18/UBB/TOR1A/PSME4/PSMB5/USP48/USP9X/UIMC1/FOXO4/TADA3/PSMF1/SNX3	56
BP	GO:0002262	myeloid cell homeostasis	32/2306	147/18670	0.000915	0.01496	0.01151	IL6/SLC11A2/ID2/CDK6/KIT/ISG15/PIK3CD/MAFB/EPAS1/STAT1/SLC7A11/VEGFA/BMP4/JAM3/KLF2/ETS1/NFE2L1/ADAR/AMPD3/ZFP36/PRMT1/HIPK2/ERCC2/KLF13/THRA/ACIN1/AXL/BAP1/GATA3/PDE4B/STAT3/ARID4A	32
BP	GO:0035337	fatty-acyl-CoA metabolic process	13/2306	41/18670	0.0009264	0.01506	0.01159	ELOVL5/SCD/ELOVL7/ACAT1/PPT1/ACACA/ACSL5/CBR4/ELOVL2/ABCD1/HSD17B12/FAR1/ELOVL3	13
BP	GO:0061028	establishment of endothelial barrier	13/2306	41/18670	0.0009264	0.01506	0.01159	ICAM1/IL1B/S1PR3/CLDN1/VEGFA/ROCK1/PDE4D/MYADM/RDX/TNF/ROCK2/ENG/TJP1	13
BP	GO:0035303	regulation of dephosphorylation	42/2306	209/18670	0.0009296	0.01506	0.01159	BMP2/ITGA1/ENSA/PPP4R4/PPP1R15A/ROCK1/PPP2R1B/PDGFRB/SET/CALM1/PPP1R12A/SLC39A10/DMPK/SEMA4D/PPP1R9B/TGFB2/ITGA2/PHACTR2/CCDC8/NUAK1/RCAN1/MEF2C/ADORA1/RGN/TNF/PPP2R5E/CALM2/FKBP1A/TMEM225/PRKCD/ANKLE2/ROCK2/PPP2R5C/ELL/PPP1R14C/PPP1R7/FARP1/SH3RF2/RCAN2/SHOC2/MYO1D/CHP2	42
BP	GO:0045599	negative regulation of fat cell differentiation	15/2306	51/18670	0.0009315	0.01506	0.01159	IL6/TRIB2/FOXO1/WWTR1/SORT1/MSX2/TRIB3/ZFP36L2/ENPP1/ARNTL/MMP11/SIRT1/WNT5A/TNF/GATA3	15
BP	GO:0001821	histamine secretion	6/2306	11/18670	0.0009361	0.01506	0.01159	CSF2/SNX4/ADA/EDN1/VAMP7/NPPA	6
BP	GO:0006853	carnitine shuttle	6/2306	11/18670	0.0009361	0.01506	0.01159	ACACB/CPT1A/ACACA/SLC25A20/PRKAB2/MID1IP1	6
BP	GO:0032874	positive regulation of stress-activated MAPK cascade	36/2306	172/18670	0.0009765	0.01567	0.01206	BMP2/ZC3H12A/IL1B/RIPK2/SH3RF1/ERN1/TPD52L1/DAXX/ANKRD6/VEGFA/MID1/PAK1/ARL6IP5/IL26/EDN1/PRMT1/SDCBP/HIPK2/TGFB2/GADD45G/FZD8/WNT5A/TRAF2/ARHGEF5/TNF/MAP3K2/MLKL/FZD4/TLR3/PJA2/SH3RF2/GDF6/DVL2/SERPINF2/TAOK1/FZD7	36
BP	GO:0015849	organic acid transport	61/2306	333/18670	0.0009873	0.01577	0.01213	IL1B/SLC7A2/BDKRB2/SLC43A2/ADORA2A/SLC16A6/NFKBIE/ATP8B1/PDPN/SLC27A3/GLS/SLC7A11/PLA2G4A/AQP9/SLC38A2/PLIN2/ACACB/PPFIA1/FABP3/RXRA/NFE2L1/ARL6IP5/SLC16A5/THBS1/CROT/SLC3A2/EDN1/RAB3GAP1/SLC35A1/CPT1A/ACACA/RGS2/ABCC1/LRRC8E/ABCD1/PLA2G12A/RGS4/ABCC2/ADORA1/RAB3A/SYT4/ABAT/SLC38A4/SLC25A20/CLN8/STXBP1/PRKAB2/GRM2/SYT1/SLC38A6/SLC26A3/PPARG/SLC19A1/NMUR2/OSR1/P2RX7/PPFIA3/SLC38A1/MID1IP1/SLC16A9/SFXN4	61
BP	GO:0046942	carboxylic acid transport	61/2306	333/18670	0.0009873	0.01577	0.01213	IL1B/SLC7A2/BDKRB2/SLC43A2/ADORA2A/SLC16A6/NFKBIE/ATP8B1/PDPN/SLC27A3/GLS/SLC7A11/PLA2G4A/AQP9/SLC38A2/PLIN2/ACACB/PPFIA1/FABP3/RXRA/NFE2L1/ARL6IP5/SLC16A5/THBS1/CROT/SLC3A2/EDN1/RAB3GAP1/SLC35A1/CPT1A/ACACA/RGS2/ABCC1/LRRC8E/ABCD1/PLA2G12A/RGS4/ABCC2/ADORA1/RAB3A/SYT4/ABAT/SLC38A4/SLC25A20/CLN8/STXBP1/PRKAB2/GRM2/SYT1/SLC38A6/SLC26A3/PPARG/SLC19A1/NMUR2/OSR1/P2RX7/PPFIA3/SLC38A1/MID1IP1/SLC16A9/SFXN4	61
BP	GO:0110053	regulation of actin filament organization	50/2306	261/18670	0.001002	0.01596	0.01228	ICAM1/ASAP3/ARPC1A/DBN1/ROCK1/ARHGEF10/PAK1/PPFIA1/CDC42EP1/ARHGAP18/LIMA1/ACTR3/CDC42EP3/SLIT2/MYADM/ARHGAP28/FMN2/RDX/PXN/DSTN/PLEKHH2/LPAR1/FHOD1/PHLDB2/ARPC2/RGS4/CAPZA2/ARF6/ARF1/PFN2/ARHGEF5/EPS8/GSN/SH3PXD2B/TACSTD2/PRKCD/SDC4/GMFB/ABL1/ROCK2/MIR214/PDXP/EPHA1/ACTR2/TMOD2/CDC42/SERPINF2/PLEKHG2/MAGEL2/WASF2	50
BP	GO:0097529	myeloid leukocyte migration	42/2306	210/18670	0.001026	0.0163	0.01254	CXCL1/CXCL2/CXCL6/CCL20/CCL5/IL6/CXCL5/IL1B/ITGA1/CXCL10/CCL2/CCL8/CSF1/CCL7/KIT/PIK3CD/PF4V1/VEGFA/IRAK4/JAM3/CCL3L3/CXCL3/CMKLR1/SLIT2/PDE4D/CXCL11/CCL3/THBS1/EDN1/CXCL9/PDGFD/SIRPA/CCL1/TGFB2/AKIRIN1/ARHGEF5/PGF/SLAMF8/SERPINE1/PDE4B/ADAM8/CYP19A1	42
BP	GO:0042107	cytokine metabolic process	28/2306	124/18670	0.001029	0.01631	0.01255	IL6/IL1B/NFKB1/HSPB1/IRF1/TRIB2/IL1A/CEBPB/EREG/IRF7/KLF4/THBS1/ZFP36/AKAP12/INHBB/PRG3/EBI3/ERRFI1/ASB1/BCL3/WNT5A/TNF/TLR3/GATA3/BCL10/ZNF287/TICAM1/STAT3	28
BP	GO:2000060	positive regulation of ubiquitin-dependent protein catabolic process	23/2306	95/18670	0.001039	0.01641	0.01263	IL33/TRIB1/TRIB2/DAB2/PLK2/NKD2/ANKIB1/HERPUD1/NUB1/DDA1/RNF14/TRIB3/ARIH2/CSNK1E/ARIH1/RNF144B/RAD23A/CEBPA/DET1/MAGEF1/SH3RF2/DVL1/ZFAND2A	23
BP	GO:0071294	cellular response to zinc ion	9/2306	23/18670	0.001058	0.01659	0.01276	MT1G/MT1M/MT1E/MT1A/MT1X/MT2A/MT1H/MT1F/ATP13A2	9
BP	GO:0072170	metanephric tubule development	9/2306	23/18670	0.001058	0.01659	0.01276	LIF/STAT1/WWTR1/PKD2/ACAT1/YAP1/HES5/LGR4/OSR1	9
BP	GO:0072243	metanephric nephron epithelium development	9/2306	23/18670	0.001058	0.01659	0.01276	LIF/STAT1/WWTR1/PKD2/ACAT1/YAP1/HES5/LGR4/OSR1	9
BP	GO:0071902	positive regulation of protein serine/threonine kinase activity	61/2306	334/18670	0.001066	0.01661	0.01278	BMP2/IRAK2/MAP3K8/IL1B/RIPK2/ITGA1/ERN1/TPD52L1/KIT/FGF2/DAXX/PLCE1/DUSP6/VEGFA/BMP4/PAK1/PDGFRB/CD40/CALM1/PKD2/CCND1/THBS1/KIDINS220/MAP3K1/STK4/EDN1/TGFA/GHR/PDGFD/F2R/LPAR1/GADD45G/ROBO1/FZD8/SIRT1/WNT5A/TRAF2/ADORA1/GDF15/MTCP1/ARHGEF5/CCNYL1/TNF/MAP3K2/MLKL/CALM2/FZD4/PDGFC/UBB/PTPN11/FGF10/MNAT1/DUSP5/PDE5A/IGF1/DVL2/P2RX7/TAOK1/ADAM8/CRKL/ADRA2A	61
BP	GO:0009261	ribonucleotide catabolic process	11/2306	32/18670	0.001072	0.01661	0.01278	PDE4D/PDE1A/AMPD3/NUDT18/NUDT7/ACAT1/NUDT11/ABCD1/PDE4B/PDE5A/HINT1	11
BP	GO:0046685	response to arsenic-containing substance	11/2306	32/18670	0.001072	0.01661	0.01278	ZC3H12A/DAXX/GSTO1/PPIF/MKNK2/MAPK13/ABCC2/RNF4/CDKN1A/TNFRSF11B/ZFAND2A	11
BP	GO:0046949	fatty-acyl-CoA biosynthetic process	11/2306	32/18670	0.001072	0.01661	0.01278	ELOVL5/SCD/ELOVL7/ACAT1/PPT1/ACACA/ACSL5/CBR4/ELOVL2/HSD17B12/ELOVL3	11
BP	GO:0071295	cellular response to vitamin	11/2306	32/18670	0.001072	0.01661	0.01278	COL1A1/IL15/PIM1/CYP27B1/SNAI2/VDR/TNC/BGLAP/MIR125B1/GAS6/PPARG	11
BP	GO:0032649	regulation of interferon-gamma production	24/2306	101/18670	0.001082	0.01668	0.01284	ZC3H12A/IL1B/RIPK2/IL33/ISG15/PDCD1LG2/IL12A/IL18R1/PDE4D/FADD/SIRPA/EBI3/BCL3/AXL/WNT5A/HAVCR2/TNF/IL12RB2/TLR3/GATA3/ABL1/PDE4B/GAS6/SASH3	24
BP	GO:0002718	regulation of cytokine production involved in immune response	21/2306	84/18670	0.001088	0.01668	0.01284	IL6/IL1B/TNFRSF14/RSAD2/TNFRSF1B/HLA-E/IL18R1/HLA-F/IRAK3/DDX58/TGFB2/WNT5A/TRAF2/TNF/TLR3/TRIM6/GATA3/HLA-G/BCL10/TICAM1/SASH3	21
BP	GO:0051492	regulation of stress fiber assembly	21/2306	84/18670	0.001088	0.01668	0.01284	ASAP3/ROCK1/ARHGEF10/PAK1/PPFIA1/ARHGAP28/PXN/LPAR1/FHOD1/PHLDB2/PFN2/ARHGEF5/SH3PXD2B/TACSTD2/SDC4/ABL1/ROCK2/EPHA1/CDC42/SERPINF2/WASF2	21
BP	GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	36/2306	173/18670	0.001089	0.01668	0.01284	BMP2/ZC3H12A/IL1B/RIPK2/SH3RF1/ERN1/TPD52L1/DAXX/ANKRD6/VEGFA/MID1/PAK1/ARL6IP5/IL26/EDN1/PRMT1/SDCBP/HIPK2/TGFB2/GADD45G/FZD8/WNT5A/TRAF2/ARHGEF5/TNF/MAP3K2/MLKL/FZD4/TLR3/PJA2/SH3RF2/GDF6/DVL2/SERPINF2/TAOK1/FZD7	36
BP	GO:0043393	regulation of protein binding	43/2306	217/18670	0.001093	0.01668	0.01284	BMP2/RIPK2/BAG2/DAB2/ROCK1/PLK2/BMP4/GREM2/IFIT1/PIM2/ITGA4/SMARCD3/UBASH3B/CYLD/STK4/TRIB3/TCF7L2/PHLDA2/HIPK2/LDOC1/CSNK1E/MMP9/FLOT1/CARM1/MEF2C/CDK5/WNT5A/TRAF2/NKX3-1/ARF6/CRBN/IFIT2/ACTB/PLXND1/FKBP1A/PRKCD/CRMP1/ABL1/MITD1/TICAM1/CCPG1/AKTIP/DVL1	43
BP	GO:0071241	cellular response to inorganic substance	43/2306	217/18670	0.001093	0.01668	0.01284	MT1G/PTGS2/MT1M/MT1E/MT1A/SLC25A24/MT1X/MT2A/CLDN1/ID2/MT1H/MT1F/MMP3/PPARGC1A/DAXX/FOXO1/EEF2K/CFLAR/PPIF/CAMK2D/NFE2L1/PKD2/BACE1/ANK3/EDN1/ADCY7/CYP1A2/MMP9/CPNE3/MEF2C/JUNB/WNT5A/TRAF2/SYT4/MTR/XRCC4/GSN/DLG4/CEBPA/SYT1/MCOLN1/ATP13A2/CHP2	43
BP	GO:1901342	regulation of vasculature development	74/2306	422/18670	0.001109	0.01688	0.01299	SOD2/ZC3H12A/TNFAIP3/PTGS2/IL6/IL1B/CXCL10/THBS2/HSPB1/IL1A/KIT/RECK/FGF2/DDAH1/PRKCA/C3/STAT1/VEGFA/HK2/ROCK1/PLK2/CFLAR/BMP4/KLF2/CD40/RHOJ/ETS1/KLF4/HSPG2/THBS1/EGLN1/BMPER/E2F2/CARD10/ADM2/HIPK2/PDGFD/RHOB/TGFB2/ITGB8/GATA6/STARD13/MEOX2/SIRT1/MIR19B2/WNT5A/SULF1/FOXJ2/MIR137/PGF/RNH1/SPARC/MIR1-2/MIR125B1/STIM1/PTPRM/PLXND1/SP100/TLR3/HLA-G/SERPINE1/ABL1/ROCK2/MIR214/PDE3B/HTATIP2/PPARG/EPHA1/ENG/MIR199A2/AGGF1/STAT3/FOXO4/SIRT6	74
BP	GO:0014888	striated muscle adaptation	16/2306	57/18670	0.001114	0.01692	0.01302	PPARGC1A/FOXO1/CFLAR/LMNA/IL15/GATA6/ERRFI1/MEF2C/GSN/CAMK2G/ATP2A2/PPP3CA/MIR214/MYH6/NPPA/MIR199A2	16
BP	GO:0034349	glial cell apoptotic process	7/2306	15/18670	0.001132	0.01697	0.01306	CCL2/PRKCA/AKAP12/CDK5/TRAF2/PRKCD/GAS6	7
BP	GO:0042362	fat-soluble vitamin biosynthetic process	7/2306	15/18670	0.001132	0.01697	0.01306	IL1B/NFKB1/CYP27B1/SNAI2/UBIAD1/VDR/TNF	7
BP	GO:0072075	metanephric mesenchyme development	7/2306	15/18670	0.001132	0.01697	0.01306	BASP1/SIX1/STAT1/PDGFRB/PKD2/SIX4/OSR1	7
BP	GO:0072160	nephron tubule epithelial cell differentiation	7/2306	15/18670	0.001132	0.01697	0.01306	LIF/STAT1/WWTR1/YAP1/MEF2C/GATA3/OSR1	7
BP	GO:1903729	regulation of plasma membrane organization	7/2306	15/18670	0.001132	0.01697	0.01306	TGFB2/RAB3A/GSN/SYTL4/ASAP1/PRKCD/MYH9	7
BP	GO:0002544	chronic inflammatory response	8/2306	19/18670	0.001144	0.01707	0.01314	TNFAIP3/CCL5/VCAM1/PTGES/IDO1/THBS1/TNF/CYP19A1	8
BP	GO:0072074	kidney mesenchyme development	8/2306	19/18670	0.001144	0.01707	0.01314	BASP1/SIX1/STAT1/BMP4/PDGFRB/PKD2/SIX4/OSR1	8
BP	GO:0071276	cellular response to cadmium ion	12/2306	37/18670	0.001156	0.01722	0.01325	MT1G/MT1M/MT1E/MT1A/MT1X/MT2A/MT1H/MT1F/DAXX/CYP1A2/MMP9/GSN	12
BP	GO:0051092	positive regulation of NF-kappaB transcription factor activity	32/2306	149/18670	0.001161	0.01725	0.01327	ICAM1/IRAK2/IL1B/RIPK2/NFKB1/PSMA6/NFKB2/IRAK4/CFLAR/IL18R1/TRIM25/CD40/IRAK3/TRIM37/ROR1/RPS6KA4/FLOT1/CARM1/WNT5A/TRAF2/RIPK4/TNF/TLR3/LRRFIP1/RBCK1/BCL10/UBB/TICAM1/TRAPPC9/TRIM38/STAT3/ADAM8	32
BP	GO:0032872	regulation of stress-activated MAPK cascade	46/2306	237/18670	0.001179	0.01747	0.01344	BMP2/ZC3H12A/IL1B/RIPK2/SH3RF1/ERN1/TPD52L1/DAXX/FOXO1/ANKRD6/VEGFA/DNAJA1/MID1/PAK1/FAS/ARL6IP5/IL26/ITCH/CYLD/EDN1/PRMT1/SDCBP/HIPK2/SIRPA/TGFB2/DUSP3/GADD45G/FZD8/WNT5A/TRAF2/ARHGEF5/TNF/MAP3K2/MLKL/FZD4/TLR3/DUSP10/PER1/PJA2/SH3RF2/GDF6/DVL2/SERPINF2/TAOK1/FZD7/ZNF675	46
BP	GO:0071383	cellular response to steroid hormone stimulus	48/2306	250/18670	0.001189	0.01758	0.01352	ICAM1/PPARGC1A/DAB2/PGRMC2/DAXX/FOXO1/DNAJA1/CFLAR/BMP4/PAK1/RXRA/NR2F2/RNF14/FHL2/ZFP36/EDN1/LBH/UBR5/SRD5A1/ZFP36L2/ARNTL/SMYD3/ERRFI1/THRA/GJB2/YAP1/CARM1/VDR/SIRT1/ABCC2/NKX3-1/TP63/DDX5/RNF4/YWHAH/ASS1/KCTD6/GPAM/ARID1A/UFSP2/NCOR2/PER1/PPARG/CDK7/NEDD4/TADA3/NCOA6/CBFB	48
BP	GO:0006509	membrane protein ectodomain proteolysis	13/2306	42/18670	0.001192	0.01758	0.01353	IL1B/BACE2/TNFRSF1B/ROCK1/BACE1/SH3D19/PSENEN/TIMP4/TNF/MYH9/P2RX7/ADAM8/ADRA2A	13
BP	GO:0006732	coenzyme metabolic process	71/2306	403/18670	0.001216	0.01789	0.01376	NAMPT/PTGS2/CBR3/PPARGC1A/SLC2A6/GPD1L/KYNU/SLC2A1/MTHFD2L/IDO1/MAT2A/HK2/ACACB/GSTO1/ELOVL5/ENO2/ADPGK/COQ10B/NUP133/SCD/ELOVL7/IDH1/PGM2L1/GCH1/DBI/NUDT7/CROT/ACAT1/NNMT/PPT1/MTHFD2/ACSF2/PNPO/ACACA/ACSL5/CBR4/AADAT/PDSS2/CYB5A/ELOVL2/UBIAD1/PARP9/ABCD1/GAMT/COQ3/PPCS/RGN/HSD17B12/LDHB/PDHB/BHMT2/ME1/PGAM4/PDK3/ACOT8/PDXP/SUCLA2/FAR1/SLC19A1/NUP35/ALDH1L2/MMADHC/IGF1/GNMT/STAT3/ALDOC/PTS/P2RX7/SIRT6/SLC25A16/ELOVL3	71
BP	GO:0016579	protein deubiquitination	53/2306	283/18670	0.001232	0.01809	0.01391	NFKBIA/BIRC3/ZC3H12A/TNFAIP3/TNIP1/PSME2/IL33/PSMA6/PSMB10/IFIH1/BIRC2/PSMB8/PSMB7/PSME1/USP12/TNIP3/TRAF3/RAD23B/PSMB9/DDX58/PSMA3/CDC25A/ITCH/CYLD/KAT2B/DDB2/USP38/PSMA1/POLB/PSMB2/TRAF2/TRIM21/PSMB3/INO80C/RAD23A/ACTB/UBXN1/USP14/BAP1/GATA3/USP53/PSMA8/USP18/UBB/PSME4/PSMB5/USP48/USP9X/UIMC1/FOXO4/TADA3/PSMF1/SNX3	53
BP	GO:0034614	cellular response to reactive oxygen species	35/2306	168/18670	0.00124	0.01816	0.01398	SOD2/TNFAIP3/IL6/GPR37L1/MMP3/FOXO1/CFLAR/KLF2/MYB/PPIF/ETS1/PKD2/KLF4/NET1/GCH1/MAPK13/PXN/PDGFD/SIRPA/RHOB/STAT6/MMP9/AXL/SIRT1/TRAF2/RGN/CAMKK2/ADPRHL2/MTR/TXN/TNF/PRKCD/GLRX2/ABL1/SIGMAR1	35
BP	GO:1901654	response to ketone	39/2306	193/18670	0.001244	0.01817	0.01398	AKR1B1/ICAM1/CLDN1/FOXO1/AHR/PSPH/CFLAR/KLF2/PTGFR/SLIT2/CCND1/KLF4/CYBA/THBS1/OXTR/EDN1/PTGER2/SRD5A1/GLB1/ACACA/TGFB2/SMYD3/ERRFI1/GJB2/YAP1/ADCY3/SIRT1/ABCC2/NKX3-1/BCL2L1/AKAP8/TNC/BGLAP/ASS1/CPS1/ROCK2/PPARG/CDKN1A/GNG2	39
BP	GO:0014706	striated muscle tissue development	69/2306	390/18670	0.001262	0.01839	0.01415	BMP2/MAFF/ID2/MSC/PITX1/FGF2/MEIS1/JARID2/SIX1/VEGFA/CFLAR/BMP4/PAK1/POPDC2/PDGFRB/RXRA/SAP30/NR2F2/LMNA/PIM1/ACTC1/EDN1/MYOM1/ARNTL/SGCD/TGFB2/RGS2/SRPK3/GATA6/YAP1/HOXD9/FLNB/FLOT1/MEOX2/IFRD1/SIX4/MEF2C/AKIRIN1/CDK5/MIR19B2/WNT5A/RGS4/BTG2/MYOM3/DDX5/BIN3/PDLIM5/SGCG/MIR1-2/FKBP1A/ARID1A/PPP3CA/ASB2/MYH6/ENG/NPPA/SIK1/UBE4B/MIR199A2/IGF1/MYH10/CASQ1/FZD7/SGCB/EYA2/DNER/SIRT6/VAMP5/TBX3	69
BP	GO:0045682	regulation of epidermis development	21/2306	85/18670	0.001279	0.01854	0.01427	MAFF/NAB1/ROCK1/BMP4/MAFG/ZFP36/MSX2/CYP27B1/TGFB2/ERRFI1/VDR/WNT5A/KRT2/TP63/HES5/TNF/FST/ROCK2/FERMT1/SULT2B1/CBFB	21
BP	GO:1905475	regulation of protein localization to membrane	38/2306	187/18670	0.00128	0.01854	0.01427	BID/PID1/PPP3CC/DAB2/SQSTM1/SLC7A11/PDCD5/PAK1/NKD2/PPFIA1/GPC4/FYN/STX3/ANK3/SSH1/GBP1/PMAIP1/CLTC/RAB11FIP2/CLIP3/CDK5/STAC/KCNB1/ARF6/BCL2L1/TP63/MRAP2/GSN/ACTB/TNF/YWHAH/GDI1/VAMP7/TFDP1/GRIPAP1/CRKL/RER1/PICALM	38
BP	GO:0046686	response to cadmium ion	17/2306	63/18670	0.001281	0.01854	0.01427	MT1G/MT1M/MT1E/MT1A/MT1X/MT2A/MT1H/MT1F/KIT/DAXX/NUDT1/CYP1A2/CYB5A/MMP9/SLC30A1/GSN/SPARC	17
BP	GO:0009062	fatty acid catabolic process	25/2306	108/18670	0.001286	0.01857	0.01429	LPIN1/ACOX2/ACACB/AIG1/HIBCH/IRS1/NUDT7/CROT/ACAT1/HADH/ACAT2/CPT1A/AMACR/ABCD1/SESN2/ACAA2/DECR2/ABHD3/LONP2/BDH2/ACOT8/PECR/SCP2/ACOXL/ACADM	25
BP	GO:0005976	polysaccharide metabolic process	26/2306	114/18670	0.00131	0.0188	0.01446	NFKB1/PYGL/IL6ST/PPP1R3F/UGP2/CALM1/IRS1/CHST7/PGM2L1/DYRK2/PHLDA2/ENPP1/CLTC/PHKB/CSGALNACT1/HAS2/CSGALNACT2/HAS1/GYG1/HAS3/GYS2/EXT1/HS2ST1/PHKA2/IGF1/GNMT	26
BP	GO:0031670	cellular response to nutrient	19/2306	74/18670	0.001311	0.0188	0.01446	PTGS2/COL1A1/FYN/P2RY11/SSH1/CYBA/IL15/PIM1/CYP27B1/SNAI2/VDR/TNC/P2RX3/BGLAP/MIR125B1/PDXP/GAS6/PPARG/P2RX7	19
BP	GO:0072078	nephron tubule morphogenesis	19/2306	74/18670	0.001311	0.0188	0.01446	BMP2/AHI1/FGF2/SIX1/KLHL3/VEGFA/LZTS2/BMP4/IRX3/PKD2/HOXA11/SIX4/HES5/PGF/TACSTD2/GATA3/HOXB7/LGR4/OSR1	19
BP	GO:0022612	gland morphogenesis	27/2306	120/18670	0.001326	0.01896	0.01459	TNFAIP3/CSF1/NTN1/CEBPB/CFLAR/BMP4/RXRA/LIMS2/MSX2/SULF2/TGFB2/SNAI2/STAT6/LRP5/POLB/VDR/WNT5A/NKX3-1/SULF1/TP63/TNC/TNF/ELF3/PLXND1/FGF10/TBX3/NFIB	27
BP	GO:0030518	intracellular steroid hormone receptor signaling pathway	29/2306	132/18670	0.001335	0.019	0.01462	PPARGC1A/DAB2/DAXX/DNAJA1/PAK1/RNF14/FHL2/LBH/UBR5/ARNTL/YAP1/CARM1/SIRT1/NKX3-1/TP63/DDX5/RNF4/YWHAH/KCTD6/GPAM/ARID1A/UFSP2/NCOR2/PER1/CDK7/NEDD4/TADA3/NCOA6/CBFB	29
BP	GO:0055007	cardiac muscle cell differentiation	29/2306	132/18670	0.001335	0.019	0.01462	BMP2/VEGFA/BMP4/PAK1/PDGFRB/RXRA/LMNA/ACTC1/EDN1/MYOM1/SGCD/RGS2/GATA6/MEF2C/MIR19B2/RGS4/MYOM3/PDLIM5/MIR1-2/ARID1A/MYH6/NPPA/SIK1/MIR199A2/IGF1/MYH10/FZD7/SGCB/TBX3	29
BP	GO:1901617	organic hydroxy compound biosynthetic process	51/2306	271/18670	0.001349	0.01917	0.01475	BMP2/AKR1B1/CH25H/IL1B/NFKB1/PLCD3/FGF2/ACOX2/PLCE1/PLCD1/INSIG2/SLC7A11/OSBPL1A/ACACB/SCD/GCH1/CYP27B1/CYB5R2/TM7SF2/ACAT2/MC1R/TRPC1/PNPO/ACACA/TGFB2/IMPA2/MOXD1/AMACR/PSAT1/NPC1L1/SNAI2/PLCB4/ITPKA/VDR/SIRT1/WNT5A/OSBPL3/VPS35/ACAA2/HSD3B7/TNF/HSD17B7/GPAM/GATA3/ACOT8/SCP2/IDI1/IP6K3/PTS/CYP19A1/OSBPL7	51
BP	GO:0035306	positive regulation of dephosphorylation	16/2306	58/18670	0.001365	0.01931	0.01485	BMP2/ITGA1/PPP1R15A/PDGFRB/CALM1/PPP1R12A/SLC39A10/ITGA2/MEF2C/ADORA1/RGN/CALM2/PRKCD/ANKLE2/PPP1R7/CHP2	16
BP	GO:0055081	anion homeostasis	16/2306	58/18670	0.001365	0.01931	0.01485	ABCA1/XPR1/SLC7A11/CA12/FABP3/SLC12A2/ENPP1/LIPG/TLCD1/ABCD1/SIRT1/ABCC2/ADORA1/RCN3/GRM2/CPS1	16
BP	GO:0001503	ossification	70/2306	398/18670	0.001372	0.01935	0.01489	BMP2/PTGS2/IL6/ID2/NAB1/CDK6/CEBPD/CSF1/CEBPB/ISG15/IFITM1/IL6ST/TP53INP2/BMP4/WWTR1/FZD1/COL1A1/SORT1/BMPR2/VCAN/CCL3/ADAR/DHRS3/MSX2/CYP27B1/PTHLH/COL5A2/ENPP1/CLTC/SEMA4D/ERCC2/TGFB2/TMEM64/CSGALNACT1/THRA/SNAI2/GDF5/LRP5/TPM4/MEF2C/JUNB/SRGN/WNT5A/ITGA11/TP63/RANBP3L/TNC/DDX5/TNF/BGLAP/BMP2K/SH3PXD2B/SPARC/OSR2/RSPO2/CEBPA/SYNCRIP/EXT1/LGR4/NPR2/COL1A2/ASF1A/ID3/IGF1/OSR1/ZHX3/P2RX7/MYBBP1A/CBFB/SNX10	70
BP	GO:0010632	regulation of epithelial cell migration	54/2306	291/18670	0.001383	0.01946	0.01497	ZC3H12A/PTGS2/HSPB1/FGF2/PRKCA/MCC/CORO1C/VEGFA/PLK2/BMP4/CD40/SLIT2/RHOJ/IQSEC1/ETS1/NR2F2/BMPR2/EPB41L4B/KLF4/THBS1/EDN1/BMPER/CARD10/HBEGF/RHOB/TGFB2/ITGA2/HAS2/STARD13/MMP9/MEOX2/AMOTL1/MEF2C/SIRT1/MIR19B2/WNT5A/ARF6/PFN2/MIR137/SPARC/TACSTD2/PTPRM/SP100/GATA3/RTN4/MAPRE2/ABL1/ROCK2/DUSP10/PPARG/FGF10/MIR199A2/GLIPR2/ATOH8	54
BP	GO:0019882	antigen processing and presentation	44/2306	226/18670	0.001396	0.01961	0.01508	ICAM1/PSME2/RELB/TAP1/TAP2/PSMA6/PSMB10/PSMB8/PSMB7/PSME1/OSBPL1A/CTSS/HLA-E/PSMB9/HLA-F/ITGB5/PSMA3/CYBA/THBS1/RAB33A/HLA-A/CLTC/DCTN1/RAB4A/PSMA1/PSMB2/CAPZA2/RAB32/KIF4B/ARF1/PSMB3/DYNLL1/ACTR10/PSMA8/HLA-G/HLA-DQB1/YTHDF1/TAPBP/PSME4/PSMB5/DCTN3/HLA-B/HLA-H/PSMF1	44
BP	GO:0120162	positive regulation of cold-induced thermogenesis	23/2306	97/18670	0.001403	0.01966	0.01512	DIO2/PPARGC1A/LPIN1/CEBPB/EPAS1/G0S2/VEGFA/IL4R/CMKLR1/SCD/OXTR/HADH/THRA/FH/ADIPOR2/STAT6/GADD45G/APPL2/PDGFC/ADRB3/PRKAB2/SIRT6/ELOVL3	23
BP	GO:0070302	regulation of stress-activated protein kinase signaling cascade	46/2306	239/18670	0.00141	0.01972	0.01517	BMP2/ZC3H12A/IL1B/RIPK2/SH3RF1/ERN1/TPD52L1/DAXX/FOXO1/ANKRD6/VEGFA/DNAJA1/MID1/PAK1/FAS/ARL6IP5/IL26/ITCH/CYLD/EDN1/PRMT1/SDCBP/HIPK2/SIRPA/TGFB2/DUSP3/GADD45G/FZD8/WNT5A/TRAF2/ARHGEF5/TNF/MAP3K2/MLKL/FZD4/TLR3/DUSP10/PER1/PJA2/SH3RF2/GDF6/DVL2/SERPINF2/TAOK1/FZD7/ZNF675	46
BP	GO:0070661	leukocyte proliferation	55/2306	298/18670	0.001427	0.01987	0.01529	TNFAIP3/CCL5/IL6/CD70/VCAM1/IL1B/RIPK2/IL33/SH3RF1/CCL8/PSMB10/IRF1/CSF1/TNFSF9/KIT/CEBPB/NPR3/IL7R/TNFRSF14/PDCD1LG2/TNFRSF1B/AHR/BTN3A1/IDO1/IL6ST/BMP4/TNFSF13B/HLA-E/IL12A/CD40/FYN/LRRC32/FADD/SLC39A10/IL15/ADA/MAD1L1/EBI3/CLCF1/EFNB1/IMPDH2/MEF2C/HAVCR2/CD79A/PRKCD/HLA-G/SDC4/ABL1/CDKN1A/FGF10/TICAM1/PDE5A/IGF1/P2RX7/SASH3	55
BP	GO:0035115	embryonic forelimb morphogenesis	11/2306	33/18670	0.001431	0.01987	0.01529	RECK/RDH10/HOXA11/MSX2/HOXD9/TP63/OSR2/RSPO2/HOXA9/OSR1/TBX3	11
BP	GO:0051955	regulation of amino acid transport	11/2306	33/18670	0.001431	0.01987	0.01529	ADORA2A/ARL6IP5/RAB3GAP1/RGS2/RGS4/ADORA1/SYT4/ABAT/STXBP1/OSR1/P2RX7	11
BP	GO:0010043	response to zinc ion	15/2306	53/18670	0.001438	0.01993	0.01533	MT1G/MT1M/MT1E/MT1A/MT1X/VCAM1/MT2A/MT1H/MT1F/KRT14/BGLAP/ASS1/CPS1/ATP13A2/P2RX7	15
BP	GO:0008217	regulation of blood pressure	37/2306	182/18670	0.001459	0.02013	0.01549	SOD2/NAMPT/BDKRB1/PTGS2/GPR37L1/ID2/NPR3/DDAH1/AGTRAP/PDE4D/NR2F2/BMPR2/CYBA/GCH1/OXTR/NAV2/EDN1/ADM2/F2R/ADH5/NISCH/LRP5/ADORA1/ABAT/CACNA1B/UTS2R/ADRB3/NPR2/COL1A2/HBB/GAS6/PPARG/PTGS1/MYH6/NPPA/MIR199A2/SERPINF2	37
BP	GO:0019884	antigen processing and presentation of exogenous antigen	37/2306	182/18670	0.001459	0.02013	0.01549	PSME2/TAP1/TAP2/PSMA6/PSMB10/PSMB8/PSMB7/PSME1/OSBPL1A/CTSS/HLA-E/PSMB9/HLA-F/ITGB5/PSMA3/CYBA/HLA-A/CLTC/DCTN1/PSMA1/PSMB2/CAPZA2/KIF4B/ARF1/PSMB3/DYNLL1/ACTR10/PSMA8/HLA-G/HLA-DQB1/TAPBP/PSME4/PSMB5/DCTN3/HLA-B/HLA-H/PSMF1	37
BP	GO:1902105	regulation of leukocyte differentiation	51/2306	272/18670	0.001466	0.02017	0.01552	NFKBIZ/ZC3H12A/LIF/CD83/RIPK2/ID2/SH3RF1/TRIB1/CDK6/IRF1/CSF1/TNFSF9/CEBPB/IL7R/PRKCA/MAFB/BMP4/IRF7/IL12A/MYB/IL4R/SOCS1/CCL3/FADD/IL15/UBASH3B/CYLD/ADA/ZFP36L2/MITF/TMEM64/ACIN1/AXL/FBN1/TNF/BGLAP/SLAMF8/MIR125B1/TFE3/TLR3/GATA3/HLA-G/PRDM1/ABL1/DUSP10/GAS6/SASH3/ADAM8/PIAS3/ZNF675/CBFB	51
BP	GO:0006865	amino acid transport	31/2306	145/18670	0.001484	0.02033	0.01564	SLC7A2/SLC43A2/ADORA2A/NFKBIE/PDPN/GLS/SLC7A11/SLC38A2/PPFIA1/NFE2L1/ARL6IP5/SLC3A2/RAB3GAP1/RGS2/LRRC8E/RGS4/ADORA1/RAB3A/SYT4/ABAT/SLC38A4/CLN8/STXBP1/GRM2/SYT1/SLC38A6/OSR1/P2RX7/PPFIA3/SLC38A1/SFXN4	31
BP	GO:0071901	negative regulation of protein serine/threonine kinase activity	31/2306	145/18670	0.001484	0.02033	0.01564	TNFAIP3/IL1B/HSPB1/DUSP6/DNAJA1/BMP4/DUSP14/IRAK3/NR2F2/LATS2/KAT2B/RGS2/SPRY1/HEXIM2/DUSP3/LRP5/CDKN2C/SIRT1/RGS4/CDKN1C/CEBPA/DUSP16/PRKCD/ABL1/DUSP18/DUSP10/PKIG/CDKN1A/DUSP5/MIR218-1/ZNF675	31
BP	GO:0032648	regulation of interferon-beta production	14/2306	48/18670	0.001492	0.0204	0.0157	RELB/RIPK2/IRF1/IFIH1/IRF7/TRAF3/DDX58/SIRPA/FLOT1/POLR3D/TLR3/PTPN11/TICAM1/TRIM38	14
BP	GO:1900077	negative regulation of cellular response to insulin stimulus	12/2306	38/18670	0.001502	0.0205	0.01577	PID1/IL1B/PTPRE/SOCS1/SOCS3/IRS1/GRB14/ENPP1/APPL2/SOCS2/PRKCD/NCOA5	12
BP	GO:0043433	negative regulation of DNA-binding transcription factor activity	35/2306	170/18670	0.001538	0.02092	0.0161	NFKBIA/ZC3H12A/TNFAIP3/IRAK2/ID2/TRIB1/NFKBIE/TRAF3/CMKLR1/IRAK3/PKD2/KLF4/TRIM37/ITCH/PIM1/MSX2/CYLD/EIF2AK4/EGLN1/TCF7L2/SIRT1/ANXA4/TRIM21/HAVCR2/MIR1-2/SP100/TAX1BP1/RBCK1/GAS6/PYDC2/ID3/SIK1/SRI/ADORA3/ZNF675	35
BP	GO:0050663	cytokine secretion	46/2306	240/18670	0.00154	0.02092	0.0161	ZC3H12A/TNFAIP3/IL1B/RIPK2/IL33/ABCA1/IL1A/IFIH1/IFNGR1/ISG15/TNFRSF14/TNFRSF1B/BTN3A1/PANX1/GBP5/IL4R/SOCS1/CD58/LRRC32/DDX58/IL26/PANX2/CCL3/GBP1/IL17RB/AKAP12/GSDMD/MBP/F2R/CCL1/NOX5/SRGN/WNT5A/ANXA4/HAVCR2/TNF/SERPINB1/TRIM6/GATA3/LGR4/ABL1/GAS6/PYDC2/FERMT1/P2RX7/MAPKBP1	46
BP	GO:0045600	positive regulation of fat cell differentiation	17/2306	64/18670	0.001547	0.02092	0.0161	BMP2/ZC3H12A/PTGS2/ID2/CEBPB/CMKLR1/ZFP36/STK4/TMEM64/SNAI2/WNT5B/LRP5/CARM1/FNDC5/SH3PXD2B/CEBPA/PPARG	17
BP	GO:0048247	lymphocyte chemotaxis	17/2306	64/18670	0.001547	0.02092	0.0161	CCL20/CCL5/CH25H/CXCL10/CCL2/CCL8/CCL7/PIK3CD/CCL3L3/CXCL11/CCL3/SLC12A2/CCL1/WNT5A/HSD3B7/GAS6/ADAM8	17
BP	GO:0048732	gland development	75/2306	434/18670	0.001555	0.02098	0.01614	BMP2/TNFAIP3/CLDN1/ID2/CSF1/PITX1/CITED2/NTN1/CEBPB/MAFB/JARID2/ARID5B/SIX1/ALDH1A3/VEGFA/HK2/CFLAR/BMP4/DBP/OAS2/RXRA/ETS1/PKD2/CCND1/LIMS2/FADD/MSX2/OXTR/ADA/ACAT1/SULF2/LBH/SRD5A1/MAD1L1/TGFB2/ITGA2/GATA6/THRA/SNAI2/HOXD9/IGF2R/STAT6/LRP5/SIX4/POLB/ROBO1/VDR/WNT5A/NKX3-1/SULF1/ARF6/RGN/TP63/CDKN1C/TNC/TNF/HOXD3/ASS1/HOXA9/ASNS/ELF3/PLXND1/SOCS2/CEBPA/GATA3/CPS1/RTN4/ABL1/NCOR2/ORAI1/FGF10/CYP19A1/CRKL/TBX3/NFIB	75
BP	GO:1901215	negative regulation of neuron death	41/2306	208/18670	0.001562	0.02103	0.01618	SOD2/CCL2/ADORA2A/PPARGC1A/CSF1/CEBPB/NCOA7/SIX1/TNFRSF1B/SLC7A11/ROCK1/FZD1/SET/HLA-F/FYN/CHMP4B/NRBP2/PPT1/HIPK2/F2R/CLCF1/GDF5/SIX4/AXL/MEF2C/CDK5/SIRT1/TRAF2/ATG7/VPS35/BHLHB9/BCL2L1/BTG2/HYOU1/STXBP1/OXR1/EN2/BTBD10/ATP13A2/STAT3/ADAM8	41
BP	GO:0061448	connective tissue development	51/2306	273/18670	0.001591	0.02137	0.01644	BMP2/ID2/PPARGC1A/CSF1/PITX1/FGF2/ARID5B/CFLAR/BMP4/PDGFRB/COL1A1/CD44/FTO/BMPR2/HOXA11/MSX2/SCARA3/ACAT1/SULF2/EDN1/PTHLH/CYTL1/PDGFD/SOX5/ITGB8/CSGALNACT1/THRA/SNAI2/BBS2/WNT5B/GDF5/LRP5/CARM1/MEF2C/SIRT1/WNT5A/ARRDC3/SULF1/COL6A3/HES5/HOXD3/SH3PXD2B/OSR2/SERPINH1/RSPO2/UBB/GDF6/OSR1/TBL1XR1/COL5A1/NFIB	51
BP	GO:0097237	cellular response to toxic substance	47/2306	247/18670	0.00161	0.02154	0.01657	SOD2/ZC3H12A/TNFAIP3/PTGS2/IL6/GPR37L1/NFKB1/PPARGC1A/CCL7/DAXX/FOXO1/SESN1/KLF2/GSTO1/MYB/PPIF/ETS1/KLF4/NET1/GCH1/MAPK13/PDGFD/SIRPA/ADCY7/RHOB/TP53INP1/ADH5/STAT6/CYGB/UBIAD1/AXL/ITPR2/SIRT1/RGN/ABCG2/SESN2/TXN/ESD/ACTB/TNF/PRKCD/CPS1/ABL1/HBB/SIGMAR1/PTGS1/MGST2	47
BP	GO:1903362	regulation of cellular protein catabolic process	47/2306	247/18670	0.00161	0.02154	0.01657	TNFAIP3/PSME2/IL33/TRIB1/TRIB2/BAG2/DAB2/PSME1/PLK2/NKD2/RAD23B/ANKIB1/HERPUD1/NFE2L1/NUB1/DDA1/RNF14/TRIB3/RDX/SDCBP/HIPK2/ARIH2/MAP1A/CSNK1E/GNA12/ARIH1/ARAF/VPS35/RNF144B/RGN/RAD23A/UBXN1/USP14/BRSK2/CEBPA/DET1/WDR91/MAGEF1/UBB/SH3RF2/FBXL5/ATP13A2/DVL1/MYLIP/ZFAND2A/OSBPL7/PSMF1	47
BP	GO:0061136	regulation of proteasomal protein catabolic process	37/2306	183/18670	0.001616	0.02157	0.01659	PSME2/IL33/TRIB1/TRIB2/BAG2/DAB2/PSME1/PLK2/NKD2/RAD23B/ANKIB1/HERPUD1/NFE2L1/NUB1/DDA1/RNF14/TRIB3/SDCBP/ARIH2/MAP1A/CSNK1E/GNA12/ARIH1/ARAF/RNF144B/RAD23A/UBXN1/USP14/BRSK2/CEBPA/DET1/UBB/SH3RF2/DVL1/ZFAND2A/OSBPL7/PSMF1	37
BP	GO:0030038	contractile actin filament bundle assembly	23/2306	98/18670	0.001623	0.02157	0.01659	ASAP3/ROCK1/ARHGEF10/PAK1/PPFIA1/ITGB5/ARHGAP28/PXN/LPAR1/FHOD1/PHLDB2/PFN2/ARHGEF5/SH3PXD2B/TACSTD2/SDC4/ZYX/ABL1/ROCK2/EPHA1/CDC42/SERPINF2/WASF2	23
BP	GO:0043149	stress fiber assembly	23/2306	98/18670	0.001623	0.02157	0.01659	ASAP3/ROCK1/ARHGEF10/PAK1/PPFIA1/ITGB5/ARHGAP28/PXN/LPAR1/FHOD1/PHLDB2/PFN2/ARHGEF5/SH3PXD2B/TACSTD2/SDC4/ZYX/ABL1/ROCK2/EPHA1/CDC42/SERPINF2/WASF2	23
BP	GO:0006936	muscle contraction	64/2306	360/18670	0.00164	0.02168	0.01668	ZC3H12A/PTGS2/ITGA1/BDKRB2/KIT/GPD1L/PLCE1/MYOF/ROCK1/VCL/GSTO1/CALD1/CALM1/ITGB5/PDE4D/CAMK2D/MYL5/OXTR/ADA/ACTC1/SULF2/EDN1/CRYAB/PXN/DMPK/MYOM1/F2R/SGCD/RGS2/ITGA2/BBS2/SYNM/HCN4/GAMT/TPM4/STAC/ADORA1/SULF1/MYOM3/MYLK/ABAT/P2RX3/CALM2/CHRNB1/ATP2A2/MIR1-2/DOCK4/ATP8A2/SNTA1/ROCK2/PDE4B/KCND3/TMOD2/MYH6/NPPA/SNTB1/NMUR2/PDE5A/SRI/TLN1/MYL12A/CASQ1/KCNB2/ADRA2A	64
BP	GO:0033619	membrane protein proteolysis	16/2306	59/18670	0.001662	0.02168	0.01668	IL1B/NFKB1/BACE2/TNFRSF1B/ROCK1/BACE1/APH1B/SH3D19/PSENEN/TIMP4/TNF/PARL/MYH9/P2RX7/ADAM8/ADRA2A	16
BP	GO:0031145	anaphase-promoting complex-dependent catabolic process	20/2306	81/18670	0.001663	0.02168	0.01668	PSME2/PSMA6/PSMB10/PSMB8/PSMB7/PSME1/PSMB9/CDC16/PSMA3/PSMA1/PSMB2/UBE2E1/PSMB3/PSMA8/UBB/PSME4/PSMB5/CDC23/UBE2S/PSMF1	20
BP	GO:0048708	astrocyte differentiation	20/2306	81/18670	0.001663	0.02168	0.01668	BMP2/IL6/GPR37L1/IL1B/LIF/ID2/ADORA2A/CDK6/IFNGR1/BACE2/IL6ST/ROR1/CLCF1/HES5/TNF/EIF2B5/ABL1/PTPN11/TSPAN2/STAT3	20
BP	GO:1901800	positive regulation of proteasomal protein catabolic process	24/2306	104/18670	0.001663	0.02168	0.01668	IL33/TRIB1/TRIB2/BAG2/DAB2/PLK2/NKD2/ANKIB1/HERPUD1/NUB1/DDA1/RNF14/TRIB3/ARIH2/CSNK1E/ARIH1/RNF144B/RAD23A/CEBPA/DET1/SH3RF2/DVL1/ZFAND2A/OSBPL7	24
BP	GO:0010649	regulation of cell communication by electrical coupling	6/2306	12/18670	0.001677	0.02168	0.01668	CALM1/PDE4D/CAMK2D/ANK3/CALM2/SRI	6
BP	GO:0042368	vitamin D biosynthetic process	6/2306	12/18670	0.001677	0.02168	0.01668	IL1B/NFKB1/CYP27B1/SNAI2/VDR/TNF	6
BP	GO:0051956	negative regulation of amino acid transport	6/2306	12/18670	0.001677	0.02168	0.01668	ARL6IP5/RGS2/RGS4/ADORA1/ABAT/OSR1	6
BP	GO:0090161	Golgi ribbon formation	6/2306	12/18670	0.001677	0.02168	0.01668	VAMP4/STX6/GCC2/OPTN/MYO18A/STX16	6
BP	GO:0097284	hepatocyte apoptotic process	6/2306	12/18670	0.001677	0.02168	0.01668	BID/CFLAR/STK4/ARF6/BCL2L1/GSN	6
BP	GO:0098974	postsynaptic actin cytoskeleton organization	6/2306	12/18670	0.001677	0.02168	0.01668	DBN1/ARF1/ACTB/MYH10/ACTG1/WASF2	6
BP	GO:0051924	regulation of calcium ion transport	48/2306	254/18670	0.001678	0.02168	0.01668	ICAM1/BDKRB1/CCL5/PTGS2/CXCL10/CCL2/ADORA2A/PDGFRB/GSTO1/RRAD/FYN/CALM1/PDE4D/CAMK2D/PKD2/CXCL11/CCL3/CYBA/UBASH3B/CXCL9/THADA/TRPC1/F2R/GJC2/GEM/STAC/RGS4/RGN/SLC30A1/MYLK/P2RX3/CACNA1B/CAMK2G/CALM2/MIR1-2/STIM1/FKBP1A/SPINK1/DIAPH1/ABL1/PDE4B/ORAI1/NPPA/SRI/P2RX7/CASQ1/HOMER2/ADRA2A	48
BP	GO:0033865	nucleoside bisphosphate metabolic process	30/2306	140/18670	0.001687	0.02168	0.01668	KYNU/TPST1/ACACB/ELOVL5/SCD/ELOVL7/DBI/NUDT7/CROT/ACAT1/PPT1/ACSF2/ENPP1/ACACA/ACSL5/CBR4/AADAT/ELOVL2/ABCD1/SULT1C4/PPCS/HSD17B12/PDHB/PAPSS1/PDK3/ACOT8/SUCLA2/FAR1/SULT2B1/ELOVL3	30
BP	GO:0033875	ribonucleoside bisphosphate metabolic process	30/2306	140/18670	0.001687	0.02168	0.01668	KYNU/TPST1/ACACB/ELOVL5/SCD/ELOVL7/DBI/NUDT7/CROT/ACAT1/PPT1/ACSF2/ENPP1/ACACA/ACSL5/CBR4/AADAT/ELOVL2/ABCD1/SULT1C4/PPCS/HSD17B12/PDHB/PAPSS1/PDK3/ACOT8/SUCLA2/FAR1/SULT2B1/ELOVL3	30
BP	GO:0034032	purine nucleoside bisphosphate metabolic process	30/2306	140/18670	0.001687	0.02168	0.01668	KYNU/TPST1/ACACB/ELOVL5/SCD/ELOVL7/DBI/NUDT7/CROT/ACAT1/PPT1/ACSF2/ENPP1/ACACA/ACSL5/CBR4/AADAT/ELOVL2/ABCD1/SULT1C4/PPCS/HSD17B12/PDHB/PAPSS1/PDK3/ACOT8/SUCLA2/FAR1/SULT2B1/ELOVL3	30
BP	GO:1903364	positive regulation of cellular protein catabolic process	30/2306	140/18670	0.001687	0.02168	0.01668	TNFAIP3/IL33/TRIB1/TRIB2/BAG2/DAB2/PLK2/NKD2/ANKIB1/HERPUD1/NUB1/DDA1/RNF14/TRIB3/RDX/ARIH2/CSNK1E/ARIH1/VPS35/RNF144B/RGN/RAD23A/CEBPA/DET1/MAGEF1/SH3RF2/FBXL5/DVL1/ZFAND2A/OSBPL7	30
BP	GO:0033559	unsaturated fatty acid metabolic process	25/2306	110/18670	0.001691	0.02168	0.01668	PTGS2/IL1B/PTGES/PLA2G4A/ELOVL5/PLA2G4C/CYP2U1/SCD/ELOVL7/EDN1/CYP1A2/ELOVL2/ABCD1/DAGLA/SIRT1/DECR2/DAGLB/ACOT8/SCP2/PTGS1/FAAH2/CYP2C19/CYP2S1/FADS3/ELOVL3	25
BP	GO:0002709	regulation of T cell mediated immunity	18/2306	70/18670	0.001705	0.02181	0.01678	IL6/IL1B/IL7R/RSAD2/TNFRSF1B/HLA-E/IL12A/IL18R1/HLA-F/FADD/HLA-A/TRAF2/GATA3/HLA-G/P2RX7/HLA-B/SASH3/HLA-H	18
BP	GO:0000910	cytokinesis	35/2306	171/18670	0.001709	0.02182	0.01679	CHMP1B/ROCK1/ANXA11/PLK2/LZTS2/ACTR3/CALM1/CHMP4B/ANK3/FMN2/SON/CDC14B/RHOB/KLHDC8B/NOX5/KIF4B/BCL2L1/ARF1/BIN3/CALM2/BIRC6/PKP4/KLHL13/CHMP5/ROCK2/PDXP/MITD1/ZFYVE19/ACTR2/PKN2/CDC42/MYH9/DCTN3/MYH10/PDCD6IP	35
BP	GO:0002687	positive regulation of leukocyte migration	28/2306	128/18670	0.001713	0.02182	0.01679	CCL20/ICAM1/BDKRB1/CCL5/IL6/CXCL10/CCL8/CSF1/CCL7/TNFRSF14/VEGFA/IL12A/CMKLR1/CCL3/FADD/ITGA4/THBS1/EDN1/PDGFD/CCL1/ITGA2/AKIRIN1/WNT5A/TNF/PGF/SERPINE1/GAS6/ADAM8	28
BP	GO:0032944	regulation of mononuclear cell proliferation	41/2306	209/18670	0.001716	0.02182	0.01679	CCL5/IL6/CD70/VCAM1/IL1B/RIPK2/SH3RF1/IRF1/CSF1/TNFSF9/CEBPB/TNFRSF14/PDCD1LG2/TNFRSF1B/AHR/IDO1/IL6ST/BMP4/TNFSF13B/HLA-E/IL12A/CD40/LRRC32/FADD/SLC39A10/IL15/ADA/MAD1L1/EBI3/CLCF1/EFNB1/MEF2C/HAVCR2/HLA-G/SDC4/CDKN1A/FGF10/TICAM1/PDE5A/IGF1/SASH3	41
BP	GO:0071248	cellular response to metal ion	38/2306	190/18670	0.001731	0.02197	0.0169	MT1G/PTGS2/MT1M/MT1E/MT1A/SLC25A24/MT1X/MT2A/CLDN1/ID2/MT1H/MT1F/PPARGC1A/DAXX/EEF2K/PPIF/CAMK2D/NFE2L1/PKD2/BACE1/ANK3/EDN1/ADCY7/CYP1A2/MMP9/CPNE3/MEF2C/JUNB/WNT5A/SYT4/XRCC4/GSN/DLG4/CEBPA/SYT1/MCOLN1/ATP13A2/CHP2	38
BP	GO:0016049	cell growth	82/2306	484/18670	0.001737	0.02197	0.0169	BDKRB1/OSGIN2/NTN1/FHL1/ZFYVE27/PLCE1/DBN1/AUTS2/VEGFA/PAK1/VCL/RERG/NDRG3/SLIT2/CAMK2D/BMPR2/NET1/RUFY3/ITGA4/CYBA/ITCH/IL17RB/EDN1/EIF2AK4/CYP27B1/CRYAB/PPT1/HBEGF/SH3BP4/ENPP1/SDCBP/SEMA4D/EPB41L3/ARIH2/DCBLD2/PPP1R9B/TGFB2/RGS2/TCHP/ADIPOR2/SMARCA2/SERTAD2/IFRD1/CDKN2C/DACT3/CDK5/SIRT1/MIR19B2/WNT5A/RGS4/SYT4/SESN2/BIN3/FLRT3/PDLIM5/IGFBPL1/BAP1/SOCS2/GDI1/SYT1/RTN4/ABL1/ZNF639/SLC25A33/PPARG/CDKN1A/NPPA/ROS1/CDC42/SEMA4F/MIR199A2/IGF1/CDH4/DVL1/TMEM108/RAPH1/USP9X/TSPYL2/CRKL/SIRT6/SGK3/ST20	82
BP	GO:0044706	multi-multicellular organism process	43/2306	222/18670	0.001742	0.02197	0.0169	AKR1B1/NAMPT/PTGS2/MAFF/IL1B/LIF/RECK/SLC2A1/IDO1/GIP/SLC38A2/PTGFR/RXRA/ETS1/PLA2G4C/NR2F2/BMPR2/OXTR/EDN1/CYP27B1/PTHLH/ARNTL/ADCY7/RGS2/ITGA2/LDOC1/GJB2/ADIPOR2/MMP9/TNP2/VDR/JUNB/ABCC2/HAVCR2/PGF/SH3PXD2B/COL16A1/PAPPA/ARID1A/PRDM1/ARHGDIB/NPPA/CAPN2	43
BP	GO:0070663	regulation of leukocyte proliferation	43/2306	222/18670	0.001742	0.02197	0.0169	TNFAIP3/CCL5/IL6/CD70/VCAM1/IL1B/RIPK2/SH3RF1/CCL8/IRF1/CSF1/TNFSF9/CEBPB/TNFRSF14/PDCD1LG2/TNFRSF1B/AHR/IDO1/IL6ST/BMP4/TNFSF13B/HLA-E/IL12A/CD40/LRRC32/FADD/SLC39A10/IL15/ADA/MAD1L1/EBI3/CLCF1/EFNB1/MEF2C/HAVCR2/HLA-G/SDC4/CDKN1A/FGF10/TICAM1/PDE5A/IGF1/SASH3	43
BP	GO:0006929	substrate-dependent cell migration	10/2306	29/18670	0.00175	0.02198	0.01691	NTN1/SLIT2/SDCBP/ITGA2/SNAI2/ROBO1/ITGA11/ANKS1A/MYH10/ADAM8	10
BP	GO:0050863	regulation of T cell activation	57/2306	314/18670	0.001758	0.02198	0.01691	NFKBIZ/ZC3H12A/CCL5/IL6/CD70/VCAM1/MAP3K8/IL1B/CD83/RIPK2/CCL2/SH3RF1/ADORA2A/IRF1/TNFSF9/CEBPB/IL7R/TNFRSF14/PDCD1LG2/TNFRSF1B/IDO1/IL6ST/BMP4/TNFSF13B/PAK1/HLA-E/IL12A/MYB/IL4R/SOCS1/FYN/LRRC32/FADD/IL15/CYLD/ADA/MAD1L1/SIRPA/EBI3/DUSP3/EFNB1/GSN/HAVCR2/GATA3/HLA-G/SDC4/PRDM1/ABL1/BCL10/DUSP10/PTPN11/CDC42/PDE5A/IGF1/SASH3/ADAM8/CBFB	57
BP	GO:0010524	positive regulation of calcium ion transport into cytosol	15/2306	54/18670	0.001767	0.02198	0.01691	BDKRB1/CXCL10/GSTO1/CALM1/PKD2/CXCL11/CXCL9/TRPC1/F2R/P2RX3/CALM2/ABL1/SRI/P2RX7/CASQ1	15
BP	GO:0032663	regulation of interleukin-2 production	15/2306	54/18670	0.001767	0.02198	0.01691	TNFAIP3/IL1B/CD83/RIPK2/IL1A/PDE4D/GBP1/ZFP36/TRAF2/HAVCR2/GATA3/ABL1/PDE4B/SASH3/HOMER2	15
BP	GO:0035384	thioester biosynthetic process	15/2306	54/18670	0.001767	0.02198	0.01691	ACACB/ELOVL5/SCD/ELOVL7/ACAT1/PPT1/ACACA/ACSL5/CBR4/ELOVL2/PPCS/HSD17B12/PDHB/PDK3/ELOVL3	15
BP	GO:0050994	regulation of lipid catabolic process	15/2306	54/18670	0.001767	0.02198	0.01691	IL1B/ACACB/IRS1/IDH1/CPT1A/THRA/ABCD1/ADORA1/TNF/ABHD5/PRKCD/LONP2/PDE3B/ADRA2A/CRTC3	15
BP	GO:0071616	acyl-CoA biosynthetic process	15/2306	54/18670	0.001767	0.02198	0.01691	ACACB/ELOVL5/SCD/ELOVL7/ACAT1/PPT1/ACACA/ACSL5/CBR4/ELOVL2/PPCS/HSD17B12/PDHB/PDK3/ELOVL3	15
BP	GO:0002475	antigen processing and presentation via MHC class Ib	7/2306	16/18670	0.001798	0.02216	0.01705	TAP2/HLA-E/HLA-F/HLA-A/HLA-G/HLA-B/HLA-H	7
BP	GO:0007567	parturition	7/2306	16/18670	0.001798	0.02216	0.01705	MAFF/PTGFR/PLA2G4C/OXTR/EDN1/ARNTL/LDOC1	7
BP	GO:0090036	regulation of protein kinase C signaling	7/2306	16/18670	0.001798	0.02216	0.01705	GPD1L/VEGFA/CD40/MYADM/AKAP12/MC1R/WNT5A	7
BP	GO:1902001	fatty acid transmembrane transport	7/2306	16/18670	0.001798	0.02216	0.01705	ACACB/THBS1/CPT1A/ACACA/SLC25A20/PRKAB2/MID1IP1	7
BP	GO:0007568	aging	58/2306	321/18670	0.0018	0.02216	0.01705	SOD2/ICAM1/NAMPT/PTGS2/VCAM1/CLDN1/ID2/NFKB2/CDK6/PPARGC1A/KYNU/TNFRSF1B/PLK2/PDGFRB/KRT14/PDE4D/LMNA/SLC12A2/IL15/ADA/EDN1/KRT16/CRYAB/ARNTL/ERCC2/NUDT1/GJB2/NUAK1/CARM1/POLB/NSMCE2/SIRT1/ATG7/RGN/TP63/CDKN1C/GSN/ABAT/BGLAP/ASS1/CLN8/EIF2B5/ATP8A2/NEK6/PRKCD/HLA-G/PPP3CA/GLRX2/SERPINE1/ABL1/KRTAP4-8/CDKN1A/ENG/STAT3/FOXO4/PICALM/TBX3/MORC3	58
BP	GO:0050714	positive regulation of protein secretion	50/2306	268/18670	0.001808	0.02217	0.01706	IL6/IL1B/RIPK2/IL33/KCNN4/ADORA2A/IL1A/IFIH1/IFNGR1/TNFRSF14/PANX1/GIP/HLA-E/IL4R/CD58/DDX58/IL26/PANX2/CCL3/IL17RB/GLUD1/AKAP12/GSDMD/TCF7L2/MBP/MYOM1/F2R/CCL1/TGFB2/PPIA/WNT5A/VPS35/MYO18A/ARF6/ARF1/ABAT/HAVCR2/TNF/SYTL4/DYNLL1/TRIM6/GATA3/ABL1/FERMT1/ATP13A2/IGF1/MYH10/SRI/P2RX7/ADAM8	50
BP	GO:0002699	positive regulation of immune effector process	42/2306	216/18670	0.001812	0.02217	0.01706	NFKBIZ/IL6/IL1B/RIPK2/IL33/TNFRSF14/RSAD2/C3/DDX60/HLA-E/IL12A/IL18R1/MYB/IL4R/HLA-F/CD40/DDX58/SNX4/FADD/HLA-A/EXOSC6/DHX58/CLCF1/STAT6/WNT5A/TRAF2/MYO18A/MICB/TNF/APPL2/STXBP1/TRIM6/GATA3/HLA-G/BCL10/VAMP7/NPPA/TICAM1/P2RX7/HLA-B/SASH3/HLA-H	42
BP	GO:0032869	cellular response to insulin stimulus	42/2306	216/18670	0.001812	0.02217	0.01706	PID1/IL1B/LPIN1/FOXO1/PTPRE/STAT1/EEF2K/CFLAR/ATP6V1E2/RAB13/PAK1/SOCS1/SOCS3/ATP6V0B/IRS1/GRB14/TBC1D4/ATP6V0E2/PIK3R2/TRIB3/SRD5A1/INHBB/ENPP1/PIK3R3/KAT2B/ERRFI1/SESN3/SIRT1/BGLAP/APPL2/SOCS2/PRKCD/NUCKS1/PDE3B/SLC25A33/AP3S1/PPARG/PTPN11/NCOA5/RAB31/ATP6V1E1/FOXO4	42
BP	GO:0045807	positive regulation of endocytosis	32/2306	153/18670	0.001832	0.02238	0.01722	IL1B/PPP3CC/CCL2/AHI1/DAB2/C3/VEGFA/EEF2K/IL15RA/SGIP1/CYBA/IL15/PPT1/SIRPA/ITGA2/FLOT1/CLIP3/AXL/WNT5A/MYO18A/ARF1/TNF/APPL2/ACTN4/PTX3/PPP3CA/SERPINE1/GAS6/TOR1A/PPARG/MIB1/RAB31	32
BP	GO:0002221	pattern recognition receptor signaling pathway	39/2306	197/18670	0.001844	0.02244	0.01726	NFKBIA/BIRC3/TNFAIP3/IRAK2/TNIP1/RIPK2/IRF1/IFIH1/BIRC2/RSAD2/TNIP3/DDX60/IRAK4/IRF7/CTSS/TRAF3/TSPAN6/IRAK3/TIFA/DDX58/FADD/CYBA/ITCH/CYLD/MAP3K1/DHX58/DMBT1/RAB11FIP2/FLOT1/WDFY1/HAVCR2/APPL2/TLR3/RTN4/LGR4/BCL10/UBB/PJA2/TICAM1	39
BP	GO:1904950	negative regulation of establishment of protein localization	39/2306	197/18670	0.001844	0.02244	0.01726	ZC3H12A/TNFAIP3/IL1B/IL33/RAB23/RSAD2/DNAJA1/LRRC32/IRS1/GBP1/NDFIP1/RHBDF2/HADH/INHBB/F2R/SERGEF/CDK5/SRGN/KCNB1/ANXA4/SYT4/TXN/TNF/SYTL4/SERPINB1/SP100/GDI1/PPP3CA/LGR4/RAB11FIP1/GAS6/PKIG/PTPN11/NDFIP2/PYDC2/FERMT1/MAPKBP1/ADRA2A/SNX3	39
BP	GO:0030857	negative regulation of epithelial cell differentiation	14/2306	49/18670	0.001855	0.02252	0.01733	S1PR3/STAT1/VEGFA/CCND1/MSX2/YAP1/MMP9/MIR18B/TP63/HES5/FOXJ2/MIR1-2/OSR1/TBX3	14
BP	GO:0016054	organic acid catabolic process	51/2306	275/18670	0.00187	0.02261	0.0174	LPIN1/FGF2/DDAH1/ACOX2/KYNU/GLS/IDO1/ACACB/AIG1/CD44/NAGK/HIBCH/BCKDHB/IRS1/IL4I1/NUDT7/CROT/FAH/ACAT1/GLUD1/HADH/PCYOX1/ACAT2/HNMT/CPT1A/AMACR/AADAT/ABCD1/HIBADH/CRYL1/AMT/ALDH7A1/SESN2/ACAA2/DECR2/ABAT/ADO/DDAH2/ALDH5A1/ABHD3/LONP2/BDH2/LDHD/ACOT8/ENOSF1/PECR/SCP2/ALDH1L2/ACOXL/BCAT2/ACADM	51
BP	GO:0046395	carboxylic acid catabolic process	51/2306	275/18670	0.00187	0.02261	0.0174	LPIN1/FGF2/DDAH1/ACOX2/KYNU/GLS/IDO1/ACACB/AIG1/CD44/NAGK/HIBCH/BCKDHB/IRS1/IL4I1/NUDT7/CROT/FAH/ACAT1/GLUD1/HADH/PCYOX1/ACAT2/HNMT/CPT1A/AMACR/AADAT/ABCD1/HIBADH/CRYL1/AMT/ALDH7A1/SESN2/ACAA2/DECR2/ABAT/ADO/DDAH2/ALDH5A1/ABHD3/LONP2/BDH2/LDHD/ACOT8/ENOSF1/PECR/SCP2/ALDH1L2/ACOXL/BCAT2/ACADM	51
BP	GO:0050707	regulation of cytokine secretion	41/2306	210/18670	0.001883	0.02273	0.01749	ZC3H12A/TNFAIP3/IL1B/RIPK2/IL33/IL1A/IFIH1/IFNGR1/TNFRSF14/TNFRSF1B/PANX1/IL4R/SOCS1/CD58/LRRC32/DDX58/IL26/PANX2/CCL3/GBP1/IL17RB/AKAP12/GSDMD/MBP/F2R/CCL1/SRGN/WNT5A/ANXA4/HAVCR2/TNF/SERPINB1/TRIM6/GATA3/LGR4/ABL1/GAS6/PYDC2/FERMT1/P2RX7/MAPKBP1	41
BP	GO:0006637	acyl-CoA metabolic process	24/2306	105/18670	0.001908	0.02295	0.01765	KYNU/ACACB/ELOVL5/SCD/ELOVL7/DBI/NUDT7/ACAT1/PPT1/ACSF2/ACACA/ACSL5/CBR4/AADAT/ELOVL2/ABCD1/PPCS/HSD17B12/PDHB/PDK3/ACOT8/SUCLA2/FAR1/ELOVL3	24
BP	GO:0035383	thioester metabolic process	24/2306	105/18670	0.001908	0.02295	0.01765	KYNU/ACACB/ELOVL5/SCD/ELOVL7/DBI/NUDT7/ACAT1/PPT1/ACSF2/ACACA/ACSL5/CBR4/AADAT/ELOVL2/ABCD1/PPCS/HSD17B12/PDHB/PDK3/ACOT8/SUCLA2/FAR1/ELOVL3	24
BP	GO:0014047	glutamate secretion	13/2306	44/18670	0.001914	0.02297	0.01767	ADORA2A/GLS/SLC38A2/PPFIA1/RAB3GAP1/ADORA1/RAB3A/SYT4/STXBP1/GRM2/SYT1/P2RX7/PPFIA3	13
BP	GO:0051279	regulation of release of sequestered calcium ion into cytosol	20/2306	82/18670	0.001948	0.02329	0.01792	BDKRB1/CXCL10/GSTO1/CALM1/PDE4D/CAMK2D/PKD2/CXCL11/CYBA/UBASH3B/CXCL9/TRPC1/F2R/CALM2/MIR1-2/FKBP1A/DIAPH1/ABL1/SRI/CASQ1	20
BP	GO:1905954	positive regulation of lipid localization	20/2306	82/18670	0.001948	0.02329	0.01792	NFKBIA/ZC3H12A/IL1B/NFKB1/ABCA1/C1QTNF1/C3/ACACB/MYB/FABP3/EDN1/LIPG/EHD1/SIRT1/NKX3-1/ATP8A2/PRKCD/SCP2/P2RX7/CYP19A1	20
BP	GO:0050730	regulation of peptidyl-tyrosine phosphorylation	48/2306	256/18670	0.001983	0.02366	0.0182	ICAM1/CCL5/IL6/CSF2/LIF/RIPK2/EHD4/PARP14/KIT/TNFRSF14/GPRC5A/IL6ST/VEGFA/EREG/IL12A/SOCS1/SOCS3/CD44/CD40/FYN/NEDD9/IL15/TGFA/HBEGF/GHR/SEMA4D/PDGFD/ERRFI1/CLCF1/PARP9/MIR19B2/ADORA1/HES5/TNF/DLG4/PDGFC/SPINK1/PRKCD/ABL1/GAS6/PTPN11/FGF10/IGF1/CBLB/STAT3/ARL2BP/DVL2/ADRA2A	48
BP	GO:1904427	positive regulation of calcium ion transmembrane transport	18/2306	71/18670	0.002025	0.02411	0.01855	BDKRB1/CXCL10/GSTO1/CALM1/PKD2/CXCL11/CXCL9/TRPC1/F2R/GJC2/STAC/RGN/CALM2/MIR1-2/STIM1/ABL1/SRI/CASQ1	18
BP	GO:1904035	regulation of epithelial cell apoptotic process	21/2306	88/18670	0.002036	0.0242	0.01862	ICAM1/TNFAIP3/IL6/CCL2/PPARGC1A/CFLAR/CD248/CD40/SORT1/ITGA4/THBS1/ZFP36/TCF7L2/CAST/GSN/TNF/GATA3/HLA-G/SERPINE1/ABL1/GAS6	21
BP	GO:0010951	negative regulation of endopeptidase activity	47/2306	250/18670	0.002076	0.02462	0.01894	BIRC3/PTGS2/SERPINA9/SERPINB2/SH3RF1/ADORA2A/SERPINB8/RECK/BIRC2/C3/TNFAIP8/VEGFA/CFLAR/CD44/HERPUD1/KLF4/PI3/THBS1/ANXA8/CRIM1/CRYAB/FNIP1/CAST/MMP9/MIR19B2/COL6A3/TIMP4/SPINK6/USP14/ITIH1/SERPINH1/SERPINB1/BIRC6/MAGEA3/SPINK1/WFDC3/SERPINE1/HMSD/GAS6/SERPINA4/UBE2Z/SERPINA3/CSTB/SERPINA1/SERPINF2/PICALM/PSMF1	47
BP	GO:0016197	endosomal transport	43/2306	224/18670	0.002083	0.02466	0.01897	EHD4/ABCA1/CHMP1B/SQSTM1/DENND5A/ANKRD50/RAB9A/CORO1C/RAB13/TOM1/EPS15/SORT1/CHMP4B/VAMP4/STX6/SNX4/ANXA8/MICALL1/VPS37D/GCC2/CLTC/VPS36/VPS37C/DCTN1/RHOBTB3/EHD1/ARHGAP1/VPS35/ARF6/PREPL/CCDC93/RAB9B/CHMP5/STX16/UBB/TBC1D10C/RASSF9/GRIPAP1/RNF126/ANKRD27/VPS26A/MAGEL2/PICALM	43
BP	GO:0034110	regulation of homotypic cell-cell adhesion	9/2306	25/18670	0.002101	0.02478	0.01907	CCL5/C1QTNF1/PRKCA/PDPN/ANK3/UBASH3B/RDX/ABAT/PRKCD	9
BP	GO:0061217	regulation of mesonephros development	9/2306	25/18670	0.002101	0.02478	0.01907	BASP1/SIX1/VEGFA/BMP4/SIX4/TACSTD2/GATA3/HOXB7/LGR4	9
BP	GO:0042063	gliogenesis	53/2306	290/18670	0.002146	0.02526	0.01943	BMP2/IL6/GPR37L1/IL1B/LIF/IL33/CCL2/ID2/NAB1/ADORA2A/CDK6/CSF1/IFNGR1/BACE2/TNFRSF1B/IL6ST/MXRA8/ARHGEF10/CNTNAP1/LAMB1/MYB/NFE2L1/CCL3/ROR1/GJC2/ERCC2/TGFB2/LPAR1/CLCF1/DAAM2/ASCL2/CDKN2C/CDK5/HES5/GSN/TNF/MIR125B1/EIF2B5/EIF2B4/FGF5/PHGDH/RTN4/ABL1/DUSP10/MMP24/PPARG/PTPN11/FGF10/TSPAN2/STAT3/CRKL/DNER/NFIB	53
BP	GO:0034446	substrate adhesion-dependent cell spreading	23/2306	100/18670	0.002152	0.02528	0.01945	PDPN/CORO1C/LAMB1/NEDD9/MYADM/LIMS2/HSPG2/GBP1/ITGA4/PXN/HAS2/AXL/ARPC2/TACSTD2/ACTN4/FERMT2/FZD4/MEGF9/ABL1/EPHA1/CDC42/FZD7/CRKL	23
BP	GO:0048016	inositol phosphate-mediated signaling	15/2306	55/18670	0.002157	0.0253	0.01946	PPP3CC/PLCE1/FHL2/DYRK2/LMCD1/EDN1/RCAN1/ITPR2/TNF/PPP3CA/NMUR2/RCAN2/IGF1/HOMER2/CHP2	15
BP	GO:0051963	regulation of synapse assembly	24/2306	106/18670	0.002184	0.02556	0.01967	THBS2/NTN1/SIX1/EEF2K/FZD1/GPC4/OXTR/SEMA4D/TPBG/FLRT2/SIX4/MEF2C/WNT5A/VPS35/ARF6/BHLHB9/LHFPL4/FLRT3/PDLIM5/LRRN1/SLITRK4/LRFN4/AMIGO3/LRRN3	24
BP	GO:0051209	release of sequestered calcium ion into cytosol	27/2306	124/18670	0.002198	0.02567	0.01975	BDKRB1/CXCL10/FGF2/PLCE1/GSTO1/CALM1/PDE4D/CAMK2D/PKD2/CXCL11/CCL3/CYBA/UBASH3B/CXCL9/TRPC1/F2R/ITPR2/TPCN1/CALM2/MIR1-2/FKBP1A/DIAPH1/ABL1/MCOLN1/SRI/P2RX7/CASQ1	27
BP	GO:1903828	negative regulation of cellular protein localization	25/2306	112/18670	0.002201	0.02567	0.01975	PID1/RAB23/DAB2/TP53INP2/DNAJA1/LZTS2/PPFIA1/ANKRD13A/GBP1/TRIM29/CLTC/MAP1A/CDK5/VPS35/ARF6/BCL2L1/TXN/MRAP2/SP100/GDI1/ROCK2/PKIG/FERMT1/DCLK2/PICALM	25
BP	GO:0051260	protein homooligomerization	62/2306	351/18670	0.002243	0.02611	0.02009	SOD2/BID/CLDN1/EHD4/C1QTNF1/GLS/ALDH1A3/SLC22A1/LNX1/HINT3/ACACB/GBP5/RXRA/TIFA/CHMP4B/PKD2/VWF/GBP1/GCH1/ACAT1/PRMT1/GSDMD/FGFRL1/CRYAB/DPYSL3/CRYZ/CPT1A/ACACA/CBR4/FLOT1/EHD1/KCTD3/IMPDH2/TRAF2/KCNB1/VPS35/KCND1/CRBN/TP63/P2RX3/ATL1/MLKL/APPL2/CD79A/IAPP/KCTD6/ALDH5A1/HLA-G/SYT1/PEX11B/BCL10/KCND3/TOR1A/MCOLN1/SIGMAR1/GNMT/SMARCAD1/KCNB2/PRTG/PDCD6IP/CRTC3/NPM2	62
BP	GO:0072593	reactive oxygen species metabolic process	52/2306	284/18670	0.002254	0.02619	0.02015	SOD2/ZC3H12A/ICAM1/PTGS2/PID1/IL1B/SLC7A2/MMP3/BIRC2/DDAH1/FOXO1/SESN1/HK2/CFLAR/KLF2/PDGFRB/FYN/PKD2/KLF4/CYBA/GCH1/THBS1/GLA/EDN1/CRYAB/PMAIP1/SIRPA/PRG3/CYP1A2/NDUFS4/ABCD1/NOX5/RGN/SESN2/TNF/PARL/SH3PXD2B/ASS1/DDAH2/PTX3/PRKCD/CPS1/PDK3/ROCK2/HBB/VDAC1/SLC25A33/CDKN1A/TICAM1/MIR199A2/STAT3/P2RX7	52
BP	GO:0032608	interferon-beta production	14/2306	50/18670	0.002288	0.02653	0.02041	RELB/RIPK2/IRF1/IFIH1/IRF7/TRAF3/DDX58/SIRPA/FLOT1/POLR3D/TLR3/PTPN11/TICAM1/TRIM38	14
BP	GO:0051224	negative regulation of protein transport	38/2306	193/18670	0.002314	0.02678	0.0206	ZC3H12A/TNFAIP3/IL1B/IL33/RAB23/RSAD2/LRRC32/IRS1/GBP1/NDFIP1/RHBDF2/HADH/INHBB/F2R/SERGEF/CDK5/SRGN/KCNB1/ANXA4/SYT4/TXN/TNF/SYTL4/SERPINB1/SP100/GDI1/PPP3CA/LGR4/RAB11FIP1/GAS6/PKIG/PTPN11/NDFIP2/PYDC2/FERMT1/MAPKBP1/ADRA2A/SNX3	38
BP	GO:0051056	regulation of small GTPase mediated signal transduction	60/2306	338/18670	0.002326	0.02685	0.02066	CYTH3/ABCA1/CSF1/SQSTM1/PSD4/PLCE1/SIPA1L1/AUTS2/ARHGEF10/PDGFRB/CGNL1/ARHGAP18/SLIT2/RHOJ/IQSEC1/NET1/ARHGAP28/PIK3R2/RDX/STMN3/F2R/RHOB/TGFB2/FGD4/SPRY1/LPAR1/CHN1/GNA13/FGD1/STARD13/FLOT1/RHOU/ROBO1/ARHGAP1/ARF6/FAM13B/ARHGEF5/EPS8/DGKI/TIAM2/ARHGEF17/ARHGAP10/ARHGEF12/RALBP1/GDI1/ARHGAP24/INPP5B/ARHGAP21/MAPRE2/PLEKHG4/ABL1/ARHGDIB/FARP1/FGF10/CDC42/IGF1/SHOC2/NGEF/PLEKHG2/CRKL	60
BP	GO:2000058	regulation of ubiquitin-dependent protein catabolic process	31/2306	149/18670	0.00233	0.02685	0.02066	IL33/TRIB1/TRIB2/DAB2/PLK2/NKD2/RAD23B/ANKIB1/HERPUD1/NUB1/DDA1/RNF14/TRIB3/SDCBP/HIPK2/ARIH2/MAP1A/CSNK1E/GNA12/ARIH1/ARAF/RNF144B/RAD23A/UBXN1/USP14/CEBPA/DET1/MAGEF1/SH3RF2/DVL1/ZFAND2A	31
BP	GO:0032728	positive regulation of interferon-beta production	10/2306	30/18670	0.002338	0.02685	0.02066	RIPK2/IRF1/IFIH1/IRF7/DDX58/FLOT1/POLR3D/TLR3/PTPN11/TICAM1	10
BP	GO:0061082	myeloid leukocyte cytokine production	10/2306	30/18670	0.002338	0.02685	0.02066	KIT/IRAK3/DDX58/TGFB2/SIRT1/WNT5A/HLA-G/BCL10/GAS6/TICAM1	10
BP	GO:0055013	cardiac muscle cell development	21/2306	89/18670	0.002361	0.02707	0.02083	VEGFA/BMP4/PAK1/PDGFRB/LMNA/ACTC1/EDN1/MYOM1/SGCD/RGS2/MIR19B2/RGS4/MYOM3/PDLIM5/MYH6/NPPA/MIR199A2/IGF1/MYH10/SGCB/TBX3	21
BP	GO:0106106	cold-induced thermogenesis	30/2306	143/18670	0.002378	0.02716	0.0209	DIO2/PPARGC1A/LPIN1/CEBPB/NPR3/EPAS1/G0S2/VEGFA/IL18R1/IL4R/CMKLR1/SCD/IL15/OXTR/HADH/ARNTL/THRA/FH/ADIPOR2/STAT6/GADD45G/ARRDC3/APPL2/TFE3/PDGFC/ADRB3/PRKAB2/LGR4/SIRT6/ELOVL3	30
BP	GO:0120161	regulation of cold-induced thermogenesis	30/2306	143/18670	0.002378	0.02716	0.0209	DIO2/PPARGC1A/LPIN1/CEBPB/NPR3/EPAS1/G0S2/VEGFA/IL18R1/IL4R/CMKLR1/SCD/IL15/OXTR/HADH/ARNTL/THRA/FH/ADIPOR2/STAT6/GADD45G/ARRDC3/APPL2/TFE3/PDGFC/ADRB3/PRKAB2/LGR4/SIRT6/ELOVL3	30
BP	GO:0002532	production of molecular mediator involved in inflammatory response	18/2306	72/18670	0.002394	0.02719	0.02092	ZC3H12A/SLC7A2/IDO1/GBP5/IL4R/SNX4/SIRPA/ADCY7/ABCD1/SLAMF8/APPL2/BAP1/SERPINE1/DUSP10/PER1/VAMP7/NPPA/TICAM1	18
BP	GO:1902903	regulation of supramolecular fiber organization	62/2306	352/18670	0.002402	0.02719	0.02092	ICAM1/ASAP3/ARPC1A/DBN1/ROCK1/ARHGEF10/MID1/PAK1/PPFIA1/CDC42EP1/ARHGAP18/LIMA1/ACTR3/CDC42EP3/SLIT2/MYADM/ARHGAP28/FMN2/EDN1/CRYAB/RDX/PXN/DSTN/DCTN1/PLEKHH2/MAP1A/LPAR1/FHOD1/CLIP3/MEF2C/PHLDB2/ARPC2/RGS4/CAPZA2/ARF6/ARF1/PFN2/ARHGEF5/EPS8/GSN/SH3PXD2B/TACSTD2/MIR1-2/IAPP/PRKCD/SDC4/GMFB/ABL1/ROCK2/MIR214/PDXP/EPHA1/ACTR2/TMOD2/CDC42/SERPINF2/TAOK1/PLEKHG2/MID1IP1/MAGEL2/CAMSAP1/WASF2	62
BP	GO:0002702	positive regulation of production of molecular mediator of immune response	22/2306	95/18670	0.002424	0.02719	0.02092	IL6/IL1B/IL33/TNFRSF14/RSAD2/HLA-E/IL18R1/IL4R/HLA-F/CD40/DDX58/EXOSC6/CLCF1/STAT6/WNT5A/TRAF2/TRIM6/GATA3/HLA-G/BCL10/TICAM1/SASH3	22
BP	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	22/2306	95/18670	0.002424	0.02719	0.02092	PSME2/PSMA6/PSMB10/PSMB8/FBXL2/PSMB7/PSME1/PSMB9/WWTR1/PSMA3/FBXL6/NCCRP1/PSMA1/PSMB2/PSMB3/FBXW4/PSMA8/FBXO17/PSME4/FBXL5/PSMB5/PSMF1	22
BP	GO:0055006	cardiac cell development	22/2306	95/18670	0.002424	0.02719	0.02092	VEGFA/BMP4/PAK1/PDGFRB/LMNA/ACTC1/EDN1/MYOM1/SGCD/RGS2/SPRY1/MIR19B2/RGS4/MYOM3/PDLIM5/MYH6/NPPA/MIR199A2/IGF1/MYH10/SGCB/TBX3	22
BP	GO:0034976	response to endoplasmic reticulum stress	52/2306	285/18670	0.002434	0.02719	0.02092	CCL2/ERN1/CEBPB/PPP1R15A/TBL2/UBE4A/TRIM25/FICD/HERPUD1/DNAJB9/NFE2L1/CCND1/TMEM117/LMNA/HDGF/WIPI1/THBS1/PIK3R2/TRIB3/EIF2AK4/NCCRP1/PMAIP1/DCTN1/SERP2/GRINA/DNAJC3/FLOT1/RNF5/SIRT1/TRAF2/RCN3/BCL2L1/SESN2/UBXN1/USP14/HYOU1/BRSK2/ATP2A2/TNFRSF10B/EIF2B5/ASNS/SSR1/MAGEA3/FBXO17/CTDSP2/TOR1A/UBE4B/RNF121/TSPYL2/TLN1/TMEM33/BFAR	52
BP	GO:0001893	maternal placenta development	11/2306	35/18670	0.002443	0.02719	0.02092	PTGS2/LIF/RXRA/NR2F2/BMPR2/CYP27B1/LDOC1/GJB2/VDR/JUNB/PRDM1	11
BP	GO:1905332	positive regulation of morphogenesis of an epithelium	11/2306	35/18670	0.002443	0.02719	0.02092	LIF/AHI1/SIX1/VEGFA/BMP4/SIX4/GATA3/HOXB7/LGR4/ABL1/SIRT6	11
BP	GO:0071548	response to dexamethasone	12/2306	40/18670	0.002451	0.02719	0.02092	ICAM1/CLDN1/FOXO1/CFLAR/EDN1/SRD5A1/SMYD3/ERRFI1/GJB2/ABCC2/ASS1/CPS1	12
BP	GO:0090184	positive regulation of kidney development	12/2306	40/18670	0.002451	0.02719	0.02092	LIF/BASP1/SIX1/VEGFA/CFLAR/BMP4/PDGFRB/PDGFD/SIX4/GATA3/HOXB7/LGR4	12
BP	GO:0030728	ovulation	8/2306	21/18670	0.002454	0.02719	0.02092	PTGS2/TNFAIP6/EREG/AFP/IL4R/INHBB/RGS2/SIRT1	8
BP	GO:0055093	response to hyperoxia	8/2306	21/18670	0.002454	0.02719	0.02092	FOXO1/PDGFRB/COL1A1/FAS/POLB/ATG7/PPARG/CDKN1A	8
BP	GO:0072111	cell proliferation involved in kidney development	8/2306	21/18670	0.002454	0.02719	0.02092	BMP2/STAT1/CFLAR/BMP4/PDGFRB/PDGFD/GATA3/OSR1	8
BP	GO:1901739	regulation of myoblast fusion	8/2306	21/18670	0.002454	0.02719	0.02092	CXCL10/CFLAR/IL4R/CXCL9/FLOT1/EHD1/GDF15/CAPN2	8
BP	GO:2000810	regulation of bicellular tight junction assembly	8/2306	21/18670	0.002454	0.02719	0.02092	CLDN1/ROCK1/SNAI2/TNF/ROCK2/TJP1/NPHP1/CBFB	8
BP	GO:0032946	positive regulation of mononuclear cell proliferation	28/2306	131/18670	0.002455	0.02719	0.02092	CCL5/IL6/CD70/VCAM1/IL1B/RIPK2/CSF1/TNFSF9/PDCD1LG2/IL6ST/TNFSF13B/HLA-E/IL12A/CD40/FADD/SLC39A10/IL15/ADA/EBI3/CLCF1/EFNB1/MEF2C/HAVCR2/CDKN1A/FGF10/TICAM1/IGF1/SASH3	28
BP	GO:0098754	detoxification	28/2306	131/18670	0.002455	0.02719	0.02092	SOD2/MT1G/PTGS2/MT1M/MT1E/MT1A/MT1X/MT2A/MT1H/MT1F/SESN1/GSTO1/GCH1/TP53INP1/ADH5/CYGB/UBIAD1/ABCC2/RGN/ABCG2/SESN2/TXN/SLC30A1/ESD/TNF/HBB/PTGS1/MGST2	28
BP	GO:0046632	alpha-beta T cell differentiation	23/2306	101/18670	0.002467	0.02728	0.02099	NFKBIZ/ZC3H12A/IL6/RELB/CD83/RIPK2/SH3RF1/IRF1/RSAD2/IL18R1/MYB/IL4R/SOCS1/ADA/RPL22/STAT6/BCL3/GATA3/PRDM1/ABL1/STAT3/SASH3/CBFB	23
BP	GO:0032609	interferon-gamma production	25/2306	113/18670	0.002502	0.02761	0.02124	ZC3H12A/IL1B/RIPK2/IL33/ISG15/PDCD1LG2/BTN3A1/IL12A/IL18R1/PDE4D/FADD/SIRPA/EBI3/BCL3/AXL/WNT5A/HAVCR2/TNF/IL12RB2/TLR3/GATA3/ABL1/PDE4B/GAS6/SASH3	25
BP	GO:1904951	positive regulation of establishment of protein localization	77/2306	456/18670	0.002576	0.02837	0.02183	ZC3H12A/BID/PTGS2/IL6/IL1B/PPP3CC/RIPK2/IL33/KCNN4/ADORA2A/IL1A/IFIH1/IFNGR1/TNFRSF14/PDCD5/PANX1/GIP/PAK1/HLA-E/IL4R/CD58/FYN/DDX58/IL26/PANX2/CCL3/ANK3/RUFY3/PIK3R2/IL17RB/GLUD1/UBR5/AKAP12/GSDMD/TCF7L2/MBP/MYOM1/PMAIP1/F2R/ARIH2/CCL1/TGFB2/PPIA/RHOU/CEP290/CDK5/WNT5A/KCNB1/VPS35/MYO18A/ARF6/TP63/ARF1/ARHGEF5/ABAT/HAVCR2/TNF/YWHAH/SYTL4/DYNLL1/BAP1/TRIM6/GATA3/PRKCD/ABL1/CTDSPL2/GAS6/TFDP1/FERMT1/ATP13A2/IGF1/MYH10/SRI/P2RX7/ADAM8/TMEM30B/CHP2	77
BP	GO:0097305	response to alcohol	44/2306	233/18670	0.002585	0.02842	0.02187	ICAM1/VCAM1/CLDN1/ABCA1/CCL7/BIRC2/AHR/KLF2/PTGFR/FYN/SLIT2/NFE2L1/CCND1/KLF4/CCL3/CYBA/ACTC1/PTGER2/GLB1/ADCY7/TP53INP1/ACACA/RGS2/ADCY3/POLB/ITPR2/RGS4/BCL2L1/AKAP8/TNC/EPS8/GSN/ABAT/BGLAP/SPARC/GATA3/GRIN3A/PPARG/CDKN1A/ACTR2/STAT3/OSBPL7/GNG2/GRAMD1A	44
BP	GO:0070936	protein K48-linked ubiquitination	15/2306	56/18670	0.002616	0.02866	0.02205	TNFAIP3/BIRC2/KLHL3/ITCH/UBR5/UBE2Q2/ARIH2/RNF5/UBE2E1/UBE2T/RNF4/TOPORS/TRIM38/RNF126/BFAR	15
BP	GO:0098586	cellular response to virus	15/2306	56/18670	0.002616	0.02866	0.02205	BIRC3/ZC3H12A/IFIH1/BIRC2/DDX60/IRF7/IL12A/TSPAN6/DDX58/ADAR/DHX58/BCL2L1/ARF1/TRIM6/LGALS8	15
BP	GO:0050808	synapse organization	70/2306	408/18670	0.002628	0.02875	0.02212	THBS2/NTN1/NFIA/SIX1/SIPA1L1/C3/DBN1/CAPRIN1/SLC7A11/EEF2K/FZD1/GPC4/FYN/PDZRN3/ANK3/SSH1/OXTR/SEMA4D/F2R/DCTN1/CAST/TPBG/FLRT2/SIX4/MEF2C/ITPKA/CDK5/WNT5A/VPS35/RAB3A/ARF6/BHLHB9/PCDHGC3/ARF1/LHFPL4/PFN2/TNC/ACTB/TNF/FLRT3/PDLIM5/LRRN1/CHRNB1/SPARC/STAU1/DLG4/SLITRK4/PLXND1/LRFN4/COL4A1/AMIGO3/NPTN/ABL1/ACTR2/FARP1/CDC42/PCDHB13/MYH10/DVL1/ACTG1/PCDH17/TMEM108/GRIPAP1/NEDD4/NGEF/CRKL/RER1/DNER/WASF2/LRRN3	70
BP	GO:0042108	positive regulation of cytokine biosynthetic process	17/2306	67/18670	0.002638	0.02881	0.02216	IL6/IL1B/HSPB1/IRF1/IL1A/EREG/THBS1/AKAP12/PRG3/EBI3/BCL3/WNT5A/TNF/TLR3/BCL10/TICAM1/STAT3	17
BP	GO:0014910	regulation of smooth muscle cell migration	20/2306	84/18670	0.002646	0.02884	0.02219	CCL5/TRIB1/PPARGC1A/PAK1/PDGFRB/PLAU/SLIT2/SSH1/PDGFD/ITGA2/LPAR1/HAS2/MEF2C/MIR137/DOCK4/SERPINE1/MIR214/IGF1/MIR218-1/FOXO4	20
BP	GO:0046631	alpha-beta T cell activation	29/2306	138/18670	0.00271	0.02948	0.02268	NFKBIZ/ZC3H12A/IL6/RELB/CD83/RIPK2/SH3RF1/ADORA2A/IRF1/TNFRSF14/RSAD2/HLA-E/IL12A/IL18R1/MYB/IL4R/SOCS1/IL15/ADA/EBI3/RPL22/STAT6/BCL3/GATA3/PRDM1/ABL1/STAT3/SASH3/CBFB	29
BP	GO:0045778	positive regulation of ossification	21/2306	90/18670	0.002728	0.02955	0.02273	BMP2/IL6/CEBPD/CEBPB/ISG15/IFITM1/IL6ST/BMP4/BMPR2/MSX2/TGFB2/LRP5/MEF2C/WNT5A/TP63/OSR2/CEBPA/IGF1/OSR1/ZHX3/P2RX7	21
BP	GO:0030540	female genitalia development	7/2306	17/18670	0.002734	0.02955	0.02273	SRD5A1/AXL/WNT5A/TP63/FGF10/CYP19A1/TBX3	7
BP	GO:0061298	retina vasculature development in camera-type eye	7/2306	17/18670	0.002734	0.02955	0.02273	NDP/PDGFRB/RHOJ/BMPR2/LRP5/FZD4/COL4A1	7
BP	GO:0072659	protein localization to plasma membrane	48/2306	260/18670	0.00274	0.02955	0.02273	PID1/DAB2/SQSTM1/ZFYVE27/ROCK1/RAB13/NKD2/PPFIA1/PLEKHF1/SYS1/MYADM/STX3/ANK3/GBP1/RDX/CLTC/EPB41L3/RAB11FIP2/BBS2/FLOT1/CLIP3/PPIL2/EFR3A/CDK5/STAC/OPTN/KCNB1/VPS35/RAB3A/ARF6/BCL2L1/RAMP1/PREPL/MRAP2/ACTB/TNF/STXBP1/ROCK2/GAS6/VAMP7/PACS2/RILPL1/RAB31/GRIPAP1/KCNB2/RER1/PICALM/VAMP5	48
BP	GO:0042476	odontogenesis	28/2306	132/18670	0.002756	0.02955	0.02273	BMP2/CSF1/FOXO1/BMP4/LAMB1/COL1A1/MSX2/LHX8/EDN1/TGFB2/TP63/TNC/BGLAP/OSR2/RSPO2/STIM1/DLX3/SERPINE1/COL1A2/ANKRD11/ID3/FGF10/TNFRSF11B/ROGDI/ITGA6/OSR1/CEMP1/SNX10	28
BP	GO:0019217	regulation of fatty acid metabolic process	22/2306	96/18670	0.002786	0.02955	0.02273	PTGS2/IL1B/PPARGC1A/INSIG2/GIP/ACACB/ELOVL5/FABP3/IRS1/NFE2L1/TRIB3/CPT1A/ADIPOR2/ABCD1/SIRT1/RGN/APPL2/PRKAB2/LONP2/PDK3/PPARG/MID1IP1	22
BP	GO:0014842	regulation of skeletal muscle satellite cell proliferation	6/2306	13/18670	0.00279	0.02955	0.02273	FGF2/SIX1/CFLAR/SIX5/AKIRIN1/STAT3	6
BP	GO:0036109	alpha-linolenic acid metabolic process	6/2306	13/18670	0.00279	0.02955	0.02273	ELOVL5/ELOVL2/ABCD1/ACOT8/SCP2/ELOVL3	6
BP	GO:0045779	negative regulation of bone resorption	6/2306	13/18670	0.00279	0.02955	0.02273	TNFAIP3/IL6/UBASH3B/IAPP/TNFRSF11B/P2RX7	6
BP	GO:0050872	white fat cell differentiation	6/2306	13/18670	0.00279	0.02955	0.02273	SNAI2/SIRT1/CEBPA/PPARG/FGF10/TBL1XR1	6
BP	GO:0072182	regulation of nephron tubule epithelial cell differentiation	6/2306	13/18670	0.00279	0.02955	0.02273	LIF/STAT1/WWTR1/YAP1/GATA3/OSR1	6
BP	GO:0090179	planar cell polarity pathway involved in neural tube closure	6/2306	13/18670	0.00279	0.02955	0.02273	FZD1/FZD2/WNT5A/PTK7/DVL1/DVL2	6
BP	GO:1901550	regulation of endothelial cell development	6/2306	13/18670	0.00279	0.02955	0.02273	IL1B/S1PR3/VEGFA/ROCK1/TNF/ROCK2	6
BP	GO:1903140	regulation of establishment of endothelial barrier	6/2306	13/18670	0.00279	0.02955	0.02273	IL1B/S1PR3/VEGFA/ROCK1/TNF/ROCK2	6
BP	GO:2000052	positive regulation of non-canonical Wnt signaling pathway	6/2306	13/18670	0.00279	0.02955	0.02273	DAB2/ANKRD6/CSNK1E/WNT5A/ABL1/PLEKHA4	6
BP	GO:0051283	negative regulation of sequestering of calcium ion	27/2306	126/18670	0.002794	0.02955	0.02273	BDKRB1/CXCL10/FGF2/PLCE1/GSTO1/CALM1/PDE4D/CAMK2D/PKD2/CXCL11/CCL3/CYBA/UBASH3B/CXCL9/TRPC1/F2R/ITPR2/TPCN1/CALM2/MIR1-2/FKBP1A/DIAPH1/ABL1/MCOLN1/SRI/P2RX7/CASQ1	27
BP	GO:0051496	positive regulation of stress fiber assembly	14/2306	51/18670	0.002802	0.02955	0.02273	ARHGEF10/PAK1/PXN/LPAR1/FHOD1/PFN2/ARHGEF5/SH3PXD2B/SDC4/ABL1/ROCK2/EPHA1/CDC42/SERPINF2	14
BP	GO:0072523	purine-containing compound catabolic process	14/2306	51/18670	0.002802	0.02955	0.02273	PDE4D/PDE1A/AMPD3/NUDT18/NUDT7/ADA/ACAT1/NT5C2/NUDT11/NUDT1/ABCD1/PDE4B/PDE5A/HINT1	14
BP	GO:0050670	regulation of lymphocyte proliferation	40/2306	208/18670	0.002818	0.0296	0.02277	CCL5/IL6/CD70/VCAM1/IL1B/RIPK2/SH3RF1/IRF1/TNFSF9/CEBPB/TNFRSF14/PDCD1LG2/TNFRSF1B/AHR/IDO1/IL6ST/BMP4/TNFSF13B/HLA-E/IL12A/CD40/LRRC32/FADD/SLC39A10/IL15/ADA/MAD1L1/EBI3/CLCF1/EFNB1/MEF2C/HAVCR2/HLA-G/SDC4/CDKN1A/FGF10/TICAM1/PDE5A/IGF1/SASH3	40
BP	GO:0010522	regulation of calcium ion transport into cytosol	23/2306	102/18670	0.002821	0.0296	0.02277	BDKRB1/CXCL10/GSTO1/FYN/CALM1/PDE4D/CAMK2D/PKD2/CXCL11/CYBA/UBASH3B/CXCL9/TRPC1/F2R/P2RX3/CALM2/MIR1-2/FKBP1A/DIAPH1/ABL1/SRI/P2RX7/CASQ1	23
BP	GO:1903052	positive regulation of proteolysis involved in cellular protein catabolic process	26/2306	120/18670	0.002821	0.0296	0.02277	IL33/TRIB1/TRIB2/BAG2/DAB2/PLK2/NKD2/ANKIB1/HERPUD1/NUB1/DDA1/RNF14/TRIB3/ARIH2/CSNK1E/ARIH1/RNF144B/RGN/RAD23A/CEBPA/DET1/MAGEF1/SH3RF2/DVL1/ZFAND2A/OSBPL7	26
BP	GO:0001916	positive regulation of T cell mediated cytotoxicity	9/2306	26/18670	0.002866	0.02992	0.02302	HLA-E/IL12A/HLA-F/FADD/HLA-A/HLA-G/P2RX7/HLA-B/HLA-H	9
BP	GO:0002230	positive regulation of defense response to virus by host	9/2306	26/18670	0.002866	0.02992	0.02302	ZC3H12A/STAT1/APOBEC3G/DDX58/TRAF3IP2/EIF2AK4/PARP9/TRIM6/APOBEC3F	9
BP	GO:0071711	basement membrane organization	9/2306	26/18670	0.002866	0.02992	0.02302	CTSS/LAMB1/PHLDB1/FLRT2/NID2/MMP11/PHLDB2/COL4A1/FERMT1	9
BP	GO:1903169	regulation of calcium ion transmembrane transport	31/2306	151/18670	0.00289	0.02999	0.02308	BDKRB1/CXCL10/GSTO1/RRAD/FYN/CALM1/PDE4D/CAMK2D/PKD2/CXCL11/CYBA/UBASH3B/CXCL9/THADA/TRPC1/F2R/GJC2/GEM/STAC/RGN/CALM2/MIR1-2/STIM1/FKBP1A/DIAPH1/ABL1/PDE4B/NPPA/SRI/CASQ1/ADRA2A	31
BP	GO:0002753	cytoplasmic pattern recognition receptor signaling pathway	16/2306	62/18670	0.002893	0.02999	0.02308	NFKBIA/BIRC3/TNFAIP3/IRAK2/RIPK2/IFIH1/BIRC2/DDX60/IRF7/TSPAN6/TIFA/DDX58/ITCH/CYLD/DHX58/UBB	16
BP	GO:0006521	regulation of cellular amino acid metabolic process	16/2306	62/18670	0.002893	0.02999	0.02308	PSME2/PSMA6/PSMB10/PSMB8/PSMB7/PSME1/SLC7A11/PSMB9/PSMA3/PSMA1/PSMB2/PSMB3/PSMA8/PSME4/PSMB5/PSMF1	16
BP	GO:0070265	necrotic cell death	16/2306	62/18670	0.002893	0.02999	0.02308	BIRC3/BIRC2/PYGL/CFLAR/PPIF/FAS/FADD/CYLD/TRAF2/TNF/MLKL/TMEM123/TLR3/RBCK1/MIR214/TICAM1	16
BP	GO:0048002	antigen processing and presentation of peptide antigen	37/2306	189/18670	0.002899	0.02999	0.02308	PSME2/TAP1/TAP2/PSMA6/PSMB10/PSMB8/PSMB7/PSME1/OSBPL1A/CTSS/HLA-E/PSMB9/HLA-F/ITGB5/PSMA3/CYBA/HLA-A/CLTC/DCTN1/PSMA1/PSMB2/CAPZA2/KIF4B/ARF1/PSMB3/DYNLL1/ACTR10/PSMA8/HLA-G/HLA-DQB1/TAPBP/PSME4/PSMB5/DCTN3/HLA-B/HLA-H/PSMF1	37
BP	GO:0032943	mononuclear cell proliferation	50/2306	274/18670	0.002902	0.02999	0.02308	CCL5/IL6/CD70/VCAM1/IL1B/RIPK2/SH3RF1/PSMB10/IRF1/CSF1/TNFSF9/CEBPB/IL7R/TNFRSF14/PDCD1LG2/TNFRSF1B/AHR/BTN3A1/IDO1/IL6ST/BMP4/TNFSF13B/HLA-E/IL12A/CD40/FYN/LRRC32/FADD/SLC39A10/IL15/ADA/MAD1L1/EBI3/CLCF1/EFNB1/IMPDH2/MEF2C/HAVCR2/CD79A/PRKCD/HLA-G/SDC4/ABL1/CDKN1A/FGF10/TICAM1/PDE5A/IGF1/P2RX7/SASH3	50
BP	GO:0003151	outflow tract morphogenesis	19/2306	79/18670	0.002959	0.03042	0.02341	CITED2/SIX1/VEGFA/BMP4/FZD1/BMPR2/DHRS3/MSX2/FZD2/TGFB2/GATA6/ROBO1/MEF2C/WNT5A/PLXND1/ENG/DVL2/CRKL/TBX3	19
BP	GO:0055072	iron ion homeostasis	19/2306	79/18670	0.002959	0.03042	0.02341	SLC11A2/ACO1/STEAP1/EPAS1/SLC25A28/FTH1/SLC25A37/NDFIP1/CAND1/ABCG2/HMOX2/CYBRD1/BDH2/FTHL17/STEAP2/FBXL5/ATP13A2/SRI/PICALM	19
BP	GO:0010883	regulation of lipid storage	13/2306	46/18670	0.002964	0.03042	0.02341	NFKBIA/ZC3H12A/IL6/NFKB1/ABCA1/C3/ACACB/FTO/EHD1/SIRT1/TNF/ABHD5/PPARG	13
BP	GO:0071354	cellular response to interleukin-6	13/2306	46/18670	0.002964	0.03042	0.02341	ICAM1/IL6/PID1/NFKB1/PPARGC1A/STAT1/IL6ST/SOCS3/ABCC2/MIR125B1/CEBPA/PTPN11/STAT3	13
BP	GO:0002675	positive regulation of acute inflammatory response	10/2306	31/18670	0.003074	0.03138	0.02414	PTGS2/IL6/IL1B/C2CD4B/OSMR/C3/IL6ST/HLA-E/TNF/ADAM8	10
BP	GO:0003401	axis elongation	10/2306	31/18670	0.003074	0.03138	0.02414	SIX1/BMP4/RDH10/SPRY1/YAP1/SIX4/WNT5A/TNC/PTK7/FGF10	10
BP	GO:0010762	regulation of fibroblast migration	10/2306	31/18670	0.003074	0.03138	0.02414	FGF2/CORO1C/PAK1/THBS1/AKAP12/CYGB/GNA12/APPL2/HAS1/SDC4	10
BP	GO:0035136	forelimb morphogenesis	12/2306	41/18670	0.003082	0.03138	0.02414	RECK/RDH10/HOXA11/MSX2/HOXD9/GDF5/TP63/OSR2/RSPO2/HOXA9/OSR1/TBX3	12
BP	GO:0050873	brown fat cell differentiation	12/2306	41/18670	0.003082	0.03138	0.02414	PTGS2/PPARGC1A/CEBPB/ARL4A/FTO/NUDT7/RGS2/FNDC5/SIRT1/CEBPA/DUSP10/ITGA6	12
BP	GO:0019915	lipid storage	17/2306	68/18670	0.003121	0.03172	0.0244	NFKBIA/ZC3H12A/IL6/IL1B/NFKB1/ABCA1/C3/PLIN2/ACACB/FTO/ENPP1/SOAT1/EHD1/SIRT1/TNF/ABHD5/PPARG	17
BP	GO:0046627	negative regulation of insulin receptor signaling pathway	11/2306	36/18670	0.003131	0.03173	0.02441	PID1/IL1B/PTPRE/SOCS1/SOCS3/IRS1/GRB14/ENPP1/SOCS2/PRKCD/NCOA5	11
BP	GO:0043270	positive regulation of ion transport	50/2306	275/18670	0.003132	0.03173	0.02441	BDKRB1/CCL5/IL1B/CXCL10/CCL2/ADORA2A/CEBPB/FHL1/CNKSR3/GPD1L/PDGFRB/CTSS/GSTO1/FABP3/CALM1/PKD2/CXCL11/CCL3/SNX4/ANK3/EDN1/RAB3GAP1/CXCL9/COX17/TRPC1/F2R/GJC2/STAC/ADORA1/RGN/SYT4/ARF1/MYLK/ABAT/P2RX3/CALM2/ACTN4/MIR1-2/STIM1/ATP8A2/STXBP1/PRKCD/ABL1/ORAI1/VAMP7/NPPA/SRI/P2RX7/CASQ1/ADRA2A	50
BP	GO:0060760	positive regulation of response to cytokine stimulus	15/2306	57/18670	0.003152	0.03183	0.02449	RIPK2/PARP14/IFIH1/CSF1/IRF7/DDX58/FADD/EDN1/PARP9/AXL/WNT5A/TRAF2/TRIM6/GAS6/ZBP1	15
BP	GO:1903428	positive regulation of reactive oxygen species biosynthetic process	15/2306	57/18670	0.003152	0.03183	0.02449	ICAM1/PTGS2/IL1B/DDAH1/KLF2/PKD2/KLF4/CYBA/EDN1/TNF/ASS1/DDAH2/PTX3/HBB/TICAM1	15
BP	GO:0051222	positive regulation of protein transport	71/2306	418/18670	0.003181	0.03207	0.02467	ZC3H12A/PTGS2/IL6/IL1B/RIPK2/IL33/KCNN4/ADORA2A/IL1A/IFIH1/IFNGR1/TNFRSF14/PDCD5/PANX1/GIP/PAK1/HLA-E/IL4R/CD58/FYN/DDX58/IL26/PANX2/CCL3/ANK3/RUFY3/PIK3R2/IL17RB/GLUD1/UBR5/AKAP12/GSDMD/TCF7L2/MBP/MYOM1/F2R/ARIH2/CCL1/TGFB2/PPIA/RHOU/CEP290/CDK5/WNT5A/KCNB1/VPS35/MYO18A/ARF6/ARF1/ARHGEF5/ABAT/HAVCR2/TNF/SYTL4/DYNLL1/BAP1/TRIM6/GATA3/PRKCD/ABL1/CTDSPL2/GAS6/FERMT1/ATP13A2/IGF1/MYH10/SRI/P2RX7/ADAM8/TMEM30B/CHP2	71
BP	GO:0032231	regulation of actin filament bundle assembly	22/2306	97/18670	0.003191	0.03207	0.02467	ASAP3/ROCK1/ARHGEF10/PAK1/PPFIA1/ARHGAP28/RDX/PXN/LPAR1/FHOD1/PHLDB2/PFN2/ARHGEF5/SH3PXD2B/TACSTD2/SDC4/ABL1/ROCK2/EPHA1/CDC42/SERPINF2/WASF2	22
BP	GO:1902882	regulation of response to oxidative stress	22/2306	97/18670	0.003191	0.03207	0.02467	SOD2/GPR37L1/HSPB1/MMP3/NCOA7/ACOX2/SESN1/SLC7A11/FZD1/LANCL1/FYN/GCH1/NME5/SESN3/ABCD1/SIRT1/ATG7/RGN/SESN2/TXN/TNF/OXR1	22
BP	GO:0010466	negative regulation of peptidase activity	48/2306	262/18670	0.003205	0.03215	0.02474	BIRC3/PTGS2/SERPINA9/SERPINB2/SH3RF1/ADORA2A/SERPINB8/RECK/BIRC2/C3/TNFAIP8/VEGFA/CFLAR/CD44/HERPUD1/KLF4/PI3/THBS1/ANXA8/CRIM1/CRYAB/FNIP1/CAST/MMP9/MIR19B2/COL6A3/TIMP4/UBXN1/SPINK6/USP14/ITIH1/SERPINH1/SERPINB1/BIRC6/MAGEA3/SPINK1/WFDC3/SERPINE1/HMSD/GAS6/SERPINA4/UBE2Z/SERPINA3/CSTB/SERPINA1/SERPINF2/PICALM/PSMF1	48
BP	GO:0034766	negative regulation of ion transmembrane transport	23/2306	103/18670	0.003216	0.03216	0.02475	GSTO1/RRAD/PPIF/CALM1/CAMK2D/ARL6IP5/PKD2/ANK3/THBS1/THADA/RGS2/HECW2/MMP9/GEM/RGS4/CRBN/SLC30A1/CALM2/MIR1-2/OSR1/SRI/NEDD4/ADRA2A	23
BP	GO:0044264	cellular polysaccharide metabolic process	23/2306	103/18670	0.003216	0.03216	0.02475	PYGL/IL6ST/PPP1R3F/UGP2/CALM1/IRS1/PGM2L1/DYRK2/PHLDA2/ENPP1/PHKB/CSGALNACT1/HAS2/CSGALNACT2/HAS1/GYG1/HAS3/GYS2/EXT1/HS2ST1/PHKA2/IGF1/GNMT	23
BP	GO:0007162	negative regulation of cell adhesion	52/2306	289/18670	0.003283	0.0326	0.02508	BMP2/ZC3H12A/ADORA2A/IRF1/CEBPB/C1QTNF1/TNFRSF14/PDCD1LG2/LPXN/IDO1/CORO1C/VEGFA/BMP4/IL4R/SOCS1/COL1A1/JAM2/LRRC32/MYADM/KLF4/GBP1/THBS1/UBASH3B/RDX/MBP/PODXL/MAD1L1/SEMA4D/SNAI2/DUSP3/PHLDB2/TNC/ABAT/HAVCR2/ASS1/TACSTD2/ACTN4/FZD4/PLXND1/PRKCD/HLA-G/SDC4/SERPINE1/ABL1/PDE3B/ARHGDIB/PTPN11/PDE5A/FZD7/AKNA/CBFB/CD164	52
BP	GO:0006836	neurotransmitter transport	49/2306	269/18670	0.003293	0.0326	0.02508	CSF2/ADORA2A/SLC22A2/SLC7A11/SLC22A1/PPFIA1/PNKD/ARL6IP5/STX3/BACE1/SNX4/ADA/EDN1/RAB3GAP1/PPT1/RGS2/LIN7A/FLOT1/MEF2C/CDK5/RGS4/SNAP47/RAB3A/SYT4/PREPL/PFN2/SLC30A1/ABAT/DGKI/CACNA1B/RPH3A/CLN8/ATP2A2/SNPH/STXBP1/SYT1/GRIN3A/HBB/SLC22A3/TOR1A/VAMP7/NPPA/NAPB/DVL1/LIN7C/P2RX7/PPFIA3/SLC29A1/SLC38A1	49
BP	GO:0002224	toll-like receptor signaling pathway	30/2306	146/18670	0.003298	0.0326	0.02508	NFKBIA/BIRC3/TNFAIP3/IRAK2/TNIP1/RIPK2/IRF1/BIRC2/RSAD2/TNIP3/IRAK4/IRF7/CTSS/TRAF3/IRAK3/FADD/CYBA/MAP3K1/RAB11FIP2/FLOT1/WDFY1/HAVCR2/APPL2/TLR3/RTN4/LGR4/BCL10/UBB/PJA2/TICAM1	30
BP	GO:0042542	response to hydrogen peroxide	30/2306	146/18670	0.003298	0.0326	0.02508	TNFAIP3/IL6/GPR37L1/FOXO1/STAT1/KLF2/PDGFRB/MYB/COL1A1/PPIF/FYN/ETS1/KLF4/NET1/ADA/MAPK13/CRYAB/PDGFD/SIRPA/RHOB/STAT6/AXL/SIRT1/TXN/PRKCD/GLRX2/ABL1/HBB/SIGMAR1/CAPN2	30
BP	GO:1904892	regulation of STAT cascade	30/2306	146/18670	0.003298	0.0326	0.02508	AKR1B1/CCL5/IL6/CSF2/LIF/PARP14/KIT/IL7R/IL6ST/IL12A/SOCS1/SOCS3/CD40/FYN/IL26/IL15/GHR/F2R/CLCF1/PARP9/BCL3/CDK5/MIR19B2/HES5/TNF/MIR125B1/SOCS2/IGF1/STAT3/ARL2BP	30
BP	GO:0043367	CD4-positive, alpha-beta T cell differentiation	18/2306	74/18670	0.003302	0.0326	0.02508	NFKBIZ/ZC3H12A/IL6/RELB/CD83/RIPK2/SH3RF1/RSAD2/IL18R1/MYB/IL4R/SOCS1/STAT6/BCL3/GATA3/STAT3/SASH3/CBFB	18
BP	GO:1900076	regulation of cellular response to insulin stimulus	18/2306	74/18670	0.003302	0.0326	0.02508	PID1/IL1B/PTPRE/PAK1/SOCS1/SOCS3/IRS1/GRB14/ENPP1/SESN3/SIRT1/BGLAP/APPL2/SOCS2/PRKCD/NUCKS1/PTPN11/NCOA5	18
BP	GO:0042098	T cell proliferation	36/2306	184/18670	0.003308	0.0326	0.02508	CCL5/IL6/CD70/VCAM1/IL1B/RIPK2/SH3RF1/PSMB10/IRF1/TNFSF9/CEBPB/TNFRSF14/PDCD1LG2/TNFRSF1B/BTN3A1/IDO1/IL6ST/BMP4/TNFSF13B/HLA-E/IL12A/FYN/LRRC32/FADD/IL15/MAD1L1/EBI3/EFNB1/HAVCR2/HLA-G/SDC4/ABL1/PDE5A/IGF1/P2RX7/SASH3	36
BP	GO:0043401	steroid hormone mediated signaling pathway	36/2306	184/18670	0.003308	0.0326	0.02508	PPARGC1A/DAB2/PGRMC2/DAXX/DNAJA1/BMP4/PAK1/RXRA/NR2F2/RNF14/FHL2/LBH/UBR5/ARNTL/THRA/YAP1/CARM1/VDR/SIRT1/NKX3-1/TP63/DDX5/RNF4/YWHAH/KCTD6/GPAM/ARID1A/UFSP2/NCOR2/PER1/PPARG/CDK7/NEDD4/TADA3/NCOA6/CBFB	36
BP	GO:0030178	negative regulation of Wnt signaling pathway	40/2306	210/18670	0.003361	0.03302	0.0254	BMP2/PSME2/PSMA6/PSMB10/DAB2/PSMB8/PSMB7/PSME1/FOXO1/MCC/ANKRD6/LZTS2/NKD2/PSMB9/WWTR1/FZD1/LATS2/PSMA3/CYLD/STK4/TCF7L2/TMEM64/SNAI2/WNT5B/PSMA1/PSMB2/DACT3/WNT5A/PSMB3/SHISA2/MIR1-2/PSMA8/TLE1/PSME4/FERMT1/PSMB5/DVL1/DVL2/SDHAF2/PSMF1	40
BP	GO:0043523	regulation of neuron apoptotic process	40/2306	210/18670	0.003361	0.03302	0.0254	SOD2/ITGA1/CCL2/ADORA2A/PPARGC1A/CEBPB/SIX1/ROCK1/MYB/SET/LANCL1/FYN/BACE1/CCL3/NRBP2/PPT1/UBE2M/HIPK2/F2R/TGFB2/CLCF1/GDF5/SIX4/AXL/MEF2C/CDK5/KCNB1/BHLHB9/BCL2L1/BTG2/TRIM2/TNF/HYOU1/MIR125B1/STXBP1/GATA3/OXR1/EN2/SIGMAR1/ADAM8	40
BP	GO:0043462	regulation of ATPase activity	19/2306	80/18670	0.00344	0.03346	0.02574	PLSCR1/DNAJA1/DNAJC19/PPIF/THADA/TMEM64/RAB4A/DNAJC15/CNN3/RAB3A/RGN/PFN2/NCAPH/DYNLL1/BRSK2/PXK/SETMAR/MYH6/FGF10	19
BP	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	8/2306	22/18670	0.003443	0.03346	0.02574	THBS1/SULF2/SPRY1/WNT5A/SULF1/SHISA2/MIR1-2/GATA3	8
BP	GO:0044321	response to leptin	8/2306	22/18670	0.003443	0.03346	0.02574	PID1/UGCG/CCND1/EDN1/INHBB/BBS2/SIRT1/STAT3	8
BP	GO:0045117	azole transport	8/2306	22/18670	0.003443	0.03346	0.02574	CSF2/SNX4/ADA/EDN1/SLC19A3/SLC22A3/VAMP7/NPPA	8
BP	GO:0060065	uterus development	8/2306	22/18670	0.003443	0.03346	0.02574	HOXA11/HOXA10/TGFB2/WNT5A/CDKN1C/HOXA9/GATA3/CYP19A1	8
BP	GO:0071359	cellular response to dsRNA	8/2306	22/18670	0.003443	0.03346	0.02574	NFKB1/IFIH1/IFIT1/DDX58/PDE12/FLOT1/TLR3/P2RX7	8
BP	GO:1903077	negative regulation of protein localization to plasma membrane	8/2306	22/18670	0.003443	0.03346	0.02574	PID1/DAB2/PPFIA1/GBP1/CLTC/BCL2L1/MRAP2/PICALM	8
BP	GO:0072511	divalent inorganic cation transport	81/2306	489/18670	0.003451	0.03348	0.02576	SLC39A14/ICAM1/BDKRB1/CCL5/PTGS2/SLC11A2/CXCL10/KCNN4/CCL2/CCL8/ADORA2A/FGF2/PLCE1/SLC41A2/PANX1/PDGFRB/GSTO1/RRAD/FYN/CALM1/PDE4D/CAMK2D/PKD2/CXCL11/CCL3/SLC39A10/CYBA/SLC3A2/UBASH3B/CACHD1/CYP27B1/CXCL9/SLC39A8/SLC30A9/THADA/NIPA1/TRPC1/F2R/GJC2/SLC30A7/ITPR2/GEM/VDR/CDK5/STAC/RGS4/ABCC2/TPCN1/RGN/RAMP1/SLC30A1/MYLK/P2RX3/CACNA1F/PARL/CACNA1B/CAMK2G/CALM2/ATP2A2/MIR1-2/STIM1/FKBP1A/SPINK1/DIAPH1/PPP3CA/GRIN3A/ABL1/PDE4B/VDAC1/ORAI1/GAS6/MCOLN1/NPPA/NMUR2/SRI/P2RX7/CLCA1/CASQ1/HOMER2/TMEM165/ADRA2A	81
BP	GO:0042594	response to starvation	37/2306	191/18670	0.003488	0.03378	0.02599	ZC3H12A/PPARGC1A/XPR1/FOXO1/SESN1/GABARAPL1/SLC2A1/GIP/SLC38A2/TBL2/BMPR2/FAS/WIPI1/ZFP36/ACAT1/EIF2AK4/SRD5A1/INHBB/FNIP1/PMAIP1/SESN3/DNAJC15/LRP11/SIRT1/ATG7/SESN2/PPM1D/ASNS/CPS1/KPTN/WDR45/GAS6/MAX/PPARG/CDKN1A/SIK1/MYBBP1A	37
BP	GO:0060348	bone development	41/2306	217/18670	0.003504	0.03388	0.02607	BMP2/NAB1/RAB23/PLS3/KIT/MEIS1/INSIG2/BMP4/COL1A1/BMPR2/HOXA11/DHRS3/MSX2/SCARA3/SULF2/SRD5A1/SEMA4D/CSGALNACT1/HAS2/LRP5/CARM1/MEF2C/FLI1/SULF1/COL6A3/RGN/RANBP3L/FBN1/BGLAP/SH3PXD2B/SPARC/OSR2/SERPINH1/PDGFC/NPR2/PTPN11/PIP4K2A/ANKRD11/ENG/IGF1/WASF2	41
BP	GO:0051282	regulation of sequestering of calcium ion	27/2306	128/18670	0.003521	0.034	0.02616	BDKRB1/CXCL10/FGF2/PLCE1/GSTO1/CALM1/PDE4D/CAMK2D/PKD2/CXCL11/CCL3/CYBA/UBASH3B/CXCL9/TRPC1/F2R/ITPR2/TPCN1/CALM2/MIR1-2/FKBP1A/DIAPH1/ABL1/MCOLN1/SRI/P2RX7/CASQ1	27
BP	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	20/2306	86/18670	0.003541	0.03414	0.02627	BID/ICAM1/TNFAIP3/DAXX/DAPK1/CFLAR/SORT1/FAS/FADD/THBS1/STK4/PMAIP1/DEDD2/TRAF2/BCL2L1/TNF/TNFRSF10B/SP100/ITPRIP/SERPINE1	20
BP	GO:0034101	erythrocyte homeostasis	26/2306	122/18670	0.003577	0.03443	0.02649	SLC11A2/ID2/CDK6/KIT/ISG15/MAFB/EPAS1/STAT1/VEGFA/BMP4/KLF2/ETS1/NFE2L1/ADAR/AMPD3/ZFP36/PRMT1/HIPK2/ERCC2/KLF13/THRA/ACIN1/AXL/GATA3/STAT3/ARID4A	26
BP	GO:0008202	steroid metabolic process	58/2306	331/18670	0.003646	0.03495	0.02689	BMP2/AKR1B1/CH25H/IL1B/NFKB1/ABCA1/PPARGC1A/KIT/HSD11B1/ATP8B1/ACOX2/INSIG2/OSBPL1A/ACACB/AFP/LIPA/LIMA1/RXRA/RDH8/NFE2L1/SCD/DDX20/DHRS11/ACAT1/SRD5A1/CYP27B1/CYB5R2/TM7SF2/ACAT2/ACACA/AMACR/CYP1A2/NPC1L1/SNAI2/SOAT1/VDR/SIRT1/OSBPL3/HSD17B12/ACAA2/OSBPL5/HSD3B7/TNF/YWHAH/CLN8/ACBD3/HSD17B7/CEBPA/GPAM/HSD17B6/STARD3NL/ACOT8/SCP2/IDI1/CYP2C19/CYP19A1/OSBPL7/SULT2B1	58
BP	GO:0070838	divalent metal ion transport	80/2306	483/18670	0.003648	0.03495	0.02689	SLC39A14/ICAM1/BDKRB1/CCL5/PTGS2/SLC11A2/CXCL10/KCNN4/CCL2/CCL8/ADORA2A/FGF2/PLCE1/SLC41A2/PANX1/PDGFRB/GSTO1/RRAD/FYN/CALM1/PDE4D/CAMK2D/PKD2/CXCL11/CCL3/SLC39A10/CYBA/SLC3A2/UBASH3B/CACHD1/CYP27B1/CXCL9/SLC39A8/SLC30A9/THADA/NIPA1/TRPC1/F2R/GJC2/SLC30A7/ITPR2/GEM/VDR/CDK5/STAC/RGS4/TPCN1/RGN/RAMP1/SLC30A1/MYLK/P2RX3/CACNA1F/PARL/CACNA1B/CAMK2G/CALM2/ATP2A2/MIR1-2/STIM1/FKBP1A/SPINK1/DIAPH1/PPP3CA/GRIN3A/ABL1/PDE4B/VDAC1/ORAI1/GAS6/MCOLN1/NPPA/NMUR2/SRI/P2RX7/CLCA1/CASQ1/HOMER2/TMEM165/ADRA2A	80
BP	GO:0006939	smooth muscle contraction	24/2306	110/18670	0.003648	0.03495	0.02689	PTGS2/BDKRB2/KIT/PLCE1/ROCK1/PDE4D/OXTR/ADA/SULF2/EDN1/F2R/RGS2/ITGA2/BBS2/ADORA1/SULF1/MYLK/ABAT/P2RX3/DOCK4/ROCK2/NMUR2/KCNB2/ADRA2A	24
BP	GO:0046822	regulation of nucleocytoplasmic transport	23/2306	104/18670	0.003657	0.03498	0.02691	ZC3H12A/PTGS2/IL1B/RAB23/MX2/BMP4/PPP1R12A/PIK3R2/UBR5/TCF7L2/CPSF6/CDK5/TXN/SP100/PRKCD/IWS1/CTDSPL2/GAS6/PKIG/PTPN11/FERMT1/NEDD4/CHP2	23
BP	GO:0060541	respiratory system development	38/2306	198/18670	0.003662	0.03498	0.02691	LIF/MSC/BASP1/HSD11B1/PDPN/SIX1/EPAS1/SLC7A11/ALDH1A3/VEGFA/BMP4/KLF2/PDGFRB/LIPA/RDH10/BMPR2/ADA/FGFRL1/SPRY1/GATA6/CYP1A2/ERRFI1/THRA/YAP1/SIX4/CRISPLD2/WNT5A/RCN3/RAB3A/TNC/PTK7/TNF/ASS1/SPARC/RSPO2/CEBPA/FGF10/NFIB	38
BP	GO:0010001	glial cell differentiation	41/2306	218/18670	0.003812	0.03625	0.02789	BMP2/IL6/GPR37L1/IL1B/LIF/ID2/NAB1/ADORA2A/CDK6/IFNGR1/BACE2/TNFRSF1B/IL6ST/MXRA8/ARHGEF10/CNTNAP1/NFE2L1/ROR1/ERCC2/LPAR1/CLCF1/DAAM2/CDKN2C/CDK5/HES5/GSN/TNF/EIF2B5/EIF2B4/FGF5/PHGDH/ABL1/DUSP10/MMP24/PPARG/PTPN11/FGF10/TSPAN2/STAT3/DNER/NFIB	41
BP	GO:0050807	regulation of synapse organization	41/2306	218/18670	0.003812	0.03625	0.02789	THBS2/NTN1/SIX1/SIPA1L1/DBN1/CAPRIN1/SLC7A11/EEF2K/FZD1/GPC4/FYN/SSH1/OXTR/SEMA4D/DCTN1/TPBG/FLRT2/SIX4/MEF2C/ITPKA/CDK5/WNT5A/VPS35/ARF6/BHLHB9/LHFPL4/TNF/FLRT3/PDLIM5/LRRN1/SPARC/SLITRK4/LRFN4/AMIGO3/ABL1/ACTR2/GRIPAP1/NEDD4/NGEF/CRKL/LRRN3	41
BP	GO:0046661	male sex differentiation	32/2306	160/18670	0.003818	0.03625	0.02789	ICAM1/CITED2/KIT/ARID5B/RAB13/PDGFRB/BCL2L2/CCND1/HOXA11/HOXA10/SRD5A1/LHFPL2/TGFB2/GATA6/NUDT1/RHOBTB3/ASB1/SIX4/WNT5A/NKX3-1/BCL2L1/MAMLD1/HOXA9/TLR3/GATA3/EIF2S2/LGR4/UBB/FGF10/CRKL/ARID4A/TBX3	32
BP	GO:0044272	sulfur compound biosynthetic process	37/2306	192/18670	0.003818	0.03625	0.02789	ST3GAL1/MTHFD2L/SLC7A11/MAT2A/ACACB/GSTO1/ELOVL5/B4GALT3/GSTA4/VCAN/SCD/ELOVL7/CHST7/ACAT1/PPT1/ACACA/ACSL5/CBR4/CSGALNACT1/CSGALNACT2/CHAC2/ELOVL2/HAGH/PPCS/HSD17B12/MTR/ESD/PDHB/BHMT2/PAPSS1/MTAP/ST3GAL3/PDK3/CNDP2/MGST2/ELOVL3/ST3GAL4	37
BP	GO:0072207	metanephric epithelium development	9/2306	27/18670	0.003834	0.03633	0.02795	LIF/STAT1/WWTR1/PKD2/ACAT1/YAP1/HES5/LGR4/OSR1	9
BP	GO:0010613	positive regulation of cardiac muscle hypertrophy	12/2306	42/18670	0.003838	0.03633	0.02795	PRKCA/IL6ST/ROCK1/CAMK2D/EDN1/MIR19B2/PPP3CA/ROCK2/MIR214/PDE5A/MIR199A2/IGF1	12
BP	GO:0003281	ventricular septum development	18/2306	75/18670	0.003853	0.03641	0.02801	ID2/CITED2/BMP4/FZD1/SLIT2/BMPR2/FGFRL1/FZD2/TGFB2/HECTD1/ROBO1/WNT5A/PTK7/MIR1-2/RBM15/GATA3/PRDM1/TBX3	18
BP	GO:1990845	adaptive thermogenesis	31/2306	154/18670	0.003943	0.03719	0.02862	DIO2/PPARGC1A/LPIN1/CEBPB/NPR3/EPAS1/G0S2/VEGFA/IL18R1/IL4R/CMKLR1/SCD/IL15/OXTR/HADH/ARNTL/THADA/THRA/FH/ADIPOR2/STAT6/GADD45G/ARRDC3/APPL2/TFE3/PDGFC/ADRB3/PRKAB2/LGR4/SIRT6/ELOVL3	31
BP	GO:0003156	regulation of animal organ formation	11/2306	37/18670	0.003966	0.03719	0.02862	BMP2/CITED2/SIX1/BMP4/HOXA11/PIM1/SPRY1/ROBO1/WNT5A/SULF1/FGF10	11
BP	GO:0010614	negative regulation of cardiac muscle hypertrophy	11/2306	37/18670	0.003966	0.03719	0.02862	JARID2/TNFRSF1B/FOXO1/PAK1/LMNA/RGS2/ERRFI1/RGS4/MIR1-2/MIR214/MIR199A2	11
BP	GO:0030212	hyaluronan metabolic process	11/2306	37/18670	0.003966	0.03719	0.02862	IL1B/NFKB1/FGF2/CD44/IL15/PIM1/CLTC/HAS2/ITIH1/HAS1/HAS3	11
BP	GO:0033280	response to vitamin D	11/2306	37/18670	0.003966	0.03719	0.02862	PTGS2/CXCL10/TRIM25/IL15/PIM1/CYP27B1/SNAI2/VDR/TNC/BGLAP/MIR125B1	11
BP	GO:0001569	branching involved in blood vessel morphogenesis	10/2306	32/18670	0.003984	0.0372	0.02862	VEGFA/STK4/EDN1/GNA13/RBM15/PLXND1/COL4A1/ABL1/ENG/SIRT6	10
BP	GO:0042311	vasodilation	10/2306	32/18670	0.003984	0.0372	0.02862	SOD2/ITGA1/BDKRB2/ADORA2A/GCH1/RGS2/BBS2/ADORA1/ADRB3/CPS1	10
BP	GO:0033238	regulation of cellular amine metabolic process	19/2306	81/18670	0.003985	0.0372	0.02862	PSME2/PSMA6/PSMB10/PSMB8/PSMB7/PSME1/SLC7A11/PSMB9/PNKD/PSMA3/PSMA1/PSMB2/VPS35/PSMB3/ABAT/PSMA8/PSME4/PSMB5/PSMF1	19
BP	GO:0051928	positive regulation of calcium ion transport	26/2306	123/18670	0.004015	0.03742	0.02879	BDKRB1/CCL5/CXCL10/CCL2/PDGFRB/GSTO1/CALM1/PKD2/CXCL11/CCL3/CXCL9/TRPC1/F2R/GJC2/STAC/RGN/MYLK/P2RX3/CALM2/MIR1-2/STIM1/ABL1/ORAI1/SRI/P2RX7/CASQ1	26
BP	GO:0008643	carbohydrate transport	30/2306	148/18670	0.004066	0.03782	0.0291	PID1/IL1B/SLC2A6/C3/SLC2A1/AQP9/HK2/GIP/SORT1/IRS1/TMEM144/TRIB3/EDN1/SLC35A1/ENPP1/SLC2A12/AQP7/ADIPOR2/CLIP3/SESN2/TNF/APPL2/PTPN11/SLC35B4/SLC35B1/IGF1/SLC37A1/SLC2A10/SLC35C1/SIRT6	30
BP	GO:0006112	energy reserve metabolic process	20/2306	87/18670	0.004075	0.03782	0.0291	GFPT2/PID1/PYGL/IL6ST/PPP1R3F/UGP2/CALM1/IRS1/PGM2L1/DYRK2/PHLDA2/ENPP1/PHKB/MRAP2/GYG1/ADRB3/GYS2/PHKA2/IGF1/GNMT	20
BP	GO:0010508	positive regulation of autophagy	25/2306	117/18670	0.004076	0.03782	0.0291	ZC3H12A/RIPK2/FOXO1/DAPK1/SESN1/TP53INP2/HK2/ROCK1/PLK2/PLEKHF1/PIM2/EIF2AK4/RAB3GAP1/SH3BP4/TP53INP1/SESN3/SIRT1/OPTN/TRIM21/TPCN1/CAMKK2/SESN2/PAFAH1B2/PIP4K2A/TICAM1	25
BP	GO:0043331	response to dsRNA	14/2306	53/18670	0.004112	0.03807	0.02929	NFKBIA/RIPK2/NFKB1/IFIH1/IFIT1/IRAK3/DDX58/SLC3A2/PMAIP1/PDE12/FLOT1/TLR3/TICAM1/P2RX7	14
BP	GO:0046651	lymphocyte proliferation	49/2306	272/18670	0.004124	0.03807	0.02929	CCL5/IL6/CD70/VCAM1/IL1B/RIPK2/SH3RF1/PSMB10/IRF1/TNFSF9/CEBPB/IL7R/TNFRSF14/PDCD1LG2/TNFRSF1B/AHR/BTN3A1/IDO1/IL6ST/BMP4/TNFSF13B/HLA-E/IL12A/CD40/FYN/LRRC32/FADD/SLC39A10/IL15/ADA/MAD1L1/EBI3/CLCF1/EFNB1/IMPDH2/MEF2C/HAVCR2/CD79A/PRKCD/HLA-G/SDC4/ABL1/CDKN1A/FGF10/TICAM1/PDE5A/IGF1/P2RX7/SASH3	49
BP	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	21/2306	93/18670	0.004129	0.03807	0.02929	PSME2/PSMA6/PSMB10/FHL1/PSMB8/PSMB7/PSME1/PSMB9/PSMA3/PSMA1/PSMB2/MIR19B2/PSMB3/PSMA8/ZNF830/ZFYVE19/PSME4/PSMB5/TAOK1/FOXO4/PSMF1	21
BP	GO:0032092	positive regulation of protein binding	21/2306	93/18670	0.004129	0.03807	0.02929	BMP2/RIPK2/PLK2/BMP4/STK4/TRIB3/TCF7L2/HIPK2/MMP9/FLOT1/MEF2C/CDK5/WNT5A/TRAF2/ARF6/CRBN/PLXND1/FKBP1A/ABL1/TICAM1/AKTIP	21
BP	GO:0043583	ear development	41/2306	219/18670	0.004144	0.03807	0.02929	BMP2/LRIG1/CEBPD/AHI1/NTN1/ATP8B1/MAFB/SIX1/INSIG2/ALDH1A3/BMP4/PDGFRB/RDH10/TTC39C/EDN1/BMPER/CYTL1/ROR1/FZD2/TGFB2/LIN7A/GJB2/CEP290/SIX4/WNT5A/SHROOM2/HES5/PRKRA/PTK7/SPARC/OSR2/ATP8A2/CEBPA/GATA3/SDC4/PCDH15/PTPN11/FGF10/DVL1/OSR1/DVL2	41
BP	GO:0002708	positive regulation of lymphocyte mediated immunity	23/2306	105/18670	0.004148	0.03807	0.02929	IL6/IL1B/RSAD2/C3/HLA-E/IL12A/IL18R1/HLA-F/CD40/FADD/HLA-A/EXOSC6/CLCF1/STAT6/TRAF2/MICB/TNF/GATA3/HLA-G/P2RX7/HLA-B/SASH3/HLA-H	23
BP	GO:1902750	negative regulation of cell cycle G2/M phase transition	23/2306	105/18670	0.004148	0.03807	0.02929	PSME2/PSMA6/PSMB10/FHL1/PSMB8/PSMB7/PSME1/PSMB9/PSMA3/CDC14B/PSMA1/PSMB2/MIR19B2/PSMB3/PSMA8/ZNF830/ZFYVE19/PSME4/PSMB5/TAOK1/UIMC1/FOXO4/PSMF1	23
BP	GO:1901570	fatty acid derivative biosynthetic process	22/2306	99/18670	0.004152	0.03807	0.02929	PTGS2/IL1B/PTGES/PLA2G4A/ELOVL5/SCD/ELOVL7/ACAT1/EDN1/PPT1/ACACA/PRG3/ACSL5/CBR4/ELOVL2/SIRT1/HSD17B12/BDH2/FAR1/PTGS1/MGST2/ELOVL3	22
BP	GO:0032147	activation of protein kinase activity	58/2306	333/18670	0.004167	0.03815	0.02936	BMP2/IRAK2/CCL5/MAP3K8/IL1B/RIPK2/ITGA1/ERN1/KIT/FGF2/DAXX/PLCE1/GPRC5A/DUSP6/VEGFA/BMP4/PAK1/SOCS1/THBS1/ZFP91/KIDINS220/CCDC88A/MAP3K1/STK4/TGFA/CARD10/GHR/F2R/ADCY7/TGFB2/LPAR1/ADCY9/ADCY3/GADD45G/WNT5A/TRAF2/ADORA1/GDF15/TXN/TNF/MAP3K2/MLKL/TNFRSF10B/PDGFC/TLR3/PRKCD/ABL1/UBB/GAS6/PTPN11/FGF10/DUSP5/IGF1/P2RX7/TAOK1/CRKL/ADRA2A/PRR5	58
BP	GO:0003149	membranous septum morphogenesis	5/2306	10/18670	0.004213	0.03829	0.02946	ID2/BMP4/FZD1/FZD2/TGFB2	5
BP	GO:0014049	positive regulation of glutamate secretion	5/2306	10/18670	0.004213	0.03829	0.02946	ADORA2A/RAB3GAP1/SYT4/STXBP1/P2RX7	5
BP	GO:0060513	prostatic bud formation	5/2306	10/18670	0.004213	0.03829	0.02946	BMP4/WNT5A/SULF1/TP63/FGF10	5
BP	GO:0061299	retina vasculature morphogenesis in camera-type eye	5/2306	10/18670	0.004213	0.03829	0.02946	NDP/RHOJ/LRP5/FZD4/COL4A1	5
BP	GO:0072531	pyrimidine-containing compound transmembrane transport	5/2306	10/18670	0.004213	0.03829	0.02946	AQP9/SLC28A3/SLC19A3/SLC25A33/SLC25A36	5
BP	GO:2000116	regulation of cysteine-type endopeptidase activity	44/2306	239/18670	0.00422	0.03829	0.02946	BIRC3/BID/PTGS2/RIPK2/SH3RF1/ADORA2A/BIRC2/PRR7/DAPK1/TNFAIP8/PDCD5/VEGFA/CFLAR/PSMB9/CD44/FYN/HERPUD1/FAS/ARL6IP5/KLF4/MTCH1/FADD/THBS1/CRYAB/FNIP1/PMAIP1/F2R/CAST/MMP9/ROBO1/SIRT1/TRAF2/NKX3-1/TP63/GSN/TNF/SOX7/TNFRSF10B/MAGEA3/BCL10/GAS6/PPARG/FAM162A/ST20	44
BP	GO:0003007	heart morphogenesis	47/2306	259/18670	0.004239	0.03841	0.02955	BMP2/ID2/AHI1/CITED2/SIX1/VEGFA/BMP4/FZD1/RXRA/SLIT2/BMPR2/PKD2/SMARCD3/PIM1/DHRS3/MSX2/ACTC1/FGFRL1/MYOM1/FZD2/TGFB2/SPRY1/GATA6/SNAI2/YAP1/HAS2/SETDB2/FLRT2/ROBO1/MEF2C/WNT5A/MYOM3/MIR1-2/RBM15/PLXND1/FKBP1A/GATA3/RTN4/MYH6/ENG/MIB1/UBE4B/DVL2/COL5A1/CRKL/SIRT6/TBX3	47
BP	GO:0072503	cellular divalent inorganic cation homeostasis	81/2306	493/18670	0.00429	0.03882	0.02987	SLC39A14/MT1G/BDKRB1/CCL5/MT1M/MT1E/MT1A/MT1X/S1PR3/MT2A/CXCL10/BDKRB2/CCL8/MT1H/MT1F/CCL7/FGF2/C1QTNF1/PLCE1/GSTO1/PTGFR/CMKLR1/CD40/FYN/CALM1/HERPUD1/PDE4D/CAMK2D/PKD2/CXCL11/CCL3/SLC39A10/CYBA/UBASH3B/OXTR/EDN1/PTGER2/CXCL9/DMPK/SLC39A8/SLC30A9/THADA/TRPC1/F2R/CCL1/GRINA/LPAR1/SLC30A7/TMEM64/GNA13/SYPL2/ITPR2/VDR/CDK5/WNT5A/ATP13A3/ADORA1/TPCN1/RGN/SLC30A1/P2RX3/CALM2/ATP2A2/MIR1-2/DLG4/STIM1/FKBP1A/IAPP/DIAPH1/NPTN/ABL1/IMMT/MCOLN1/NMUR2/ATP13A2/MIR199A2/CCR10/SRI/P2RX7/CASQ1/TMEM165	81
BP	GO:0019933	cAMP-mediated signaling	36/2306	187/18670	0.004355	0.03914	0.03012	CXCL10/ADORA2A/ABCA1/PRKCA/AHR/GIP/PTGFR/CALM1/PDE4D/CXCL11/PTGER2/PTHLH/CXCL9/ADM2/MC1R/ADCY7/RGS2/LPAR1/GNA13/NDUFS4/ADCY9/ADCY3/ARRDC3/RAMP1/MRAP2/GPR161/CALM2/MIR1-2/IAPP/ADRB3/LGR4/PDE3B/KSR1/ADRA2A/CRTC3/GNG2	36
BP	GO:0014841	skeletal muscle satellite cell proliferation	6/2306	14/18670	0.004377	0.03914	0.03012	FGF2/SIX1/CFLAR/SIX5/AKIRIN1/STAT3	6
BP	GO:0014857	regulation of skeletal muscle cell proliferation	6/2306	14/18670	0.004377	0.03914	0.03012	FGF2/SIX1/CFLAR/SIX5/AKIRIN1/STAT3	6
BP	GO:0030213	hyaluronan biosynthetic process	6/2306	14/18670	0.004377	0.03914	0.03012	IL1B/NFKB1/CLTC/HAS2/HAS1/HAS3	6
BP	GO:0045651	positive regulation of macrophage differentiation	6/2306	14/18670	0.004377	0.03914	0.03012	LIF/ID2/TRIB1/CSF1/PRKCA/FADD	6
BP	GO:0051775	response to redox state	6/2306	14/18670	0.004377	0.03914	0.03012	SLC7A11/NPAS2/ARNTL/ADH5/GLRX2/ARHGDIB	6
BP	GO:0090178	regulation of establishment of planar polarity involved in neural tube closure	6/2306	14/18670	0.004377	0.03914	0.03012	FZD1/FZD2/WNT5A/PTK7/DVL1/DVL2	6
BP	GO:0099188	postsynaptic cytoskeleton organization	6/2306	14/18670	0.004377	0.03914	0.03012	DBN1/ARF1/ACTB/MYH10/ACTG1/WASF2	6
BP	GO:0050671	positive regulation of lymphocyte proliferation	27/2306	130/18670	0.004402	0.03931	0.03025	CCL5/IL6/CD70/VCAM1/IL1B/RIPK2/TNFSF9/PDCD1LG2/IL6ST/TNFSF13B/HLA-E/IL12A/CD40/FADD/SLC39A10/IL15/ADA/EBI3/CLCF1/EFNB1/MEF2C/HAVCR2/CDKN1A/FGF10/TICAM1/IGF1/SASH3	27
BP	GO:0060411	cardiac septum morphogenesis	18/2306	76/18670	0.004478	0.03994	0.03073	ID2/CITED2/BMP4/FZD1/SLIT2/BMPR2/DHRS3/MSX2/FGFRL1/FZD2/TGFB2/GATA6/ROBO1/WNT5A/MIR1-2/RBM15/ENG/TBX3	18
BP	GO:0032890	regulation of organic acid transport	15/2306	59/18670	0.004495	0.04003	0.0308	IL1B/ADORA2A/FABP3/ARL6IP5/THBS1/EDN1/RAB3GAP1/RGS2/RGS4/ADORA1/SYT4/ABAT/STXBP1/OSR1/P2RX7	15
BP	GO:0009267	cellular response to starvation	30/2306	149/18670	0.004504	0.04005	0.03081	ZC3H12A/XPR1/FOXO1/SESN1/GABARAPL1/SLC2A1/SLC38A2/TBL2/BMPR2/FAS/WIPI1/EIF2AK4/SRD5A1/INHBB/FNIP1/PMAIP1/SESN3/DNAJC15/SIRT1/ATG7/SESN2/PPM1D/ASNS/KPTN/WDR45/GAS6/MAX/CDKN1A/SIK1/MYBBP1A	30
BP	GO:0030879	mammary gland development	29/2306	143/18670	0.004644	0.04113	0.03164	ID2/CSF1/NTN1/CEBPB/VEGFA/HK2/BMP4/OAS2/CCND1/MSX2/OXTR/LBH/ITGA2/HOXD9/STAT6/LRP5/ROBO1/VDR/WNT5A/HOXA9/ELF3/SOCS2/GATA3/RTN4/NCOR2/ORAI1/FGF10/CYP19A1/TBX3	29
BP	GO:0003279	cardiac septum development	24/2306	112/18670	0.004645	0.04113	0.03164	ID2/CITED2/BMP4/FZD1/SLIT2/BMPR2/DHRS3/MSX2/FGFRL1/FZD2/TGFB2/HECTD1/GATA6/ROBO1/WNT5A/PTK7/MIR1-2/RBM15/PLXND1/GATA3/PRDM1/ENG/MYH10/TBX3	24
BP	GO:0060419	heart growth	24/2306	112/18670	0.004645	0.04113	0.03164	BASP1/FGF2/MEIS1/JARID2/DUSP6/PAK1/ACACB/RXRA/PIM1/EDN1/TGFB2/RGS2/GATA6/YAP1/MEF2C/MIR19B2/RGS4/PDLIM5/MIR1-2/MYH6/NPPA/MIR199A2/IGF1/SIRT6	24
BP	GO:0050803	regulation of synapse structure or activity	42/2306	227/18670	0.004652	0.04113	0.03164	THBS2/NTN1/SIX1/SIPA1L1/DBN1/CAPRIN1/SLC7A11/EEF2K/FZD1/GPC4/FYN/SSH1/OXTR/PPT1/SEMA4D/DCTN1/TPBG/FLRT2/SIX4/MEF2C/ITPKA/CDK5/WNT5A/VPS35/ARF6/BHLHB9/LHFPL4/TNF/FLRT3/PDLIM5/LRRN1/SPARC/SLITRK4/LRFN4/AMIGO3/ABL1/ACTR2/GRIPAP1/NEDD4/NGEF/CRKL/LRRN3	42
BP	GO:0032088	negative regulation of NF-kappaB transcription factor activity	20/2306	88/18670	0.004675	0.04122	0.03171	NFKBIA/ZC3H12A/TNFAIP3/IRAK2/TRAF3/CMKLR1/IRAK3/KLF4/TRIM37/ITCH/CYLD/SIRT1/ANXA4/TRIM21/HAVCR2/TAX1BP1/RBCK1/PYDC2/ADORA3/ZNF675	20
BP	GO:0045921	positive regulation of exocytosis	20/2306	88/18670	0.004675	0.04122	0.03171	RAB9A/IL4R/HLA-F/SNX4/RAB2B/SDCBP/CDK5/KCNB1/RAB3A/SYT4/ARF1/SYTL4/STXBP5/STXBP1/SYT1/SDC4/VAMP7/NPPA/ATP13A2/PDCD6IP	20
BP	GO:0006906	vesicle fusion	21/2306	94/18670	0.004712	0.04123	0.03172	TAP1/TAP2/SAMD9L/NKD2/BET1/VAMP4/STX3/STX6/TBC1D4/SNAP47/RAB3A/SYT4/TMEM175/SAMD9/STXBP1/SYT1/STX16/VAMP7/TAPBP/TSNARE1/ANKRD27	21
BP	GO:0051043	regulation of membrane protein ectodomain proteolysis	8/2306	23/18670	0.004715	0.04123	0.03172	IL1B/TNFRSF1B/ROCK1/SH3D19/TIMP4/TNF/ADAM8/ADRA2A	8
BP	GO:0071305	cellular response to vitamin D	8/2306	23/18670	0.004715	0.04123	0.03172	IL15/PIM1/CYP27B1/SNAI2/VDR/TNC/BGLAP/MIR125B1	8
BP	GO:0007254	JNK cascade	40/2306	214/18670	0.004718	0.04123	0.03172	IRAK2/IL1B/RIPK2/SH3RF1/TRIB1/ERN1/TPD52L1/DAXX/ANKRD6/DNAJA1/IRAK4/PAK1/ITCH/CYLD/EDN1/SDCBP/HIPK2/SIRPA/DUSP3/GADD45G/FZD8/WNT5A/TRAF2/ARHGEF5/TNF/MAP3K2/MLKL/FZD4/TLR3/DUSP10/UBB/PER1/PJA2/SH3RF2/DVL2/SERPINF2/TAOK1/FZD7/CRKL/ZNF675	40
BP	GO:1903050	regulation of proteolysis involved in cellular protein catabolic process	40/2306	214/18670	0.004718	0.04123	0.03172	PSME2/IL33/TRIB1/TRIB2/BAG2/DAB2/PSME1/PLK2/NKD2/RAD23B/ANKIB1/HERPUD1/NFE2L1/NUB1/DDA1/RNF14/TRIB3/SDCBP/HIPK2/ARIH2/MAP1A/CSNK1E/GNA12/ARIH1/ARAF/RNF144B/RGN/RAD23A/UBXN1/USP14/BRSK2/CEBPA/DET1/MAGEF1/UBB/SH3RF2/DVL1/ZFAND2A/OSBPL7/PSMF1	40
BP	GO:0014742	positive regulation of muscle hypertrophy	12/2306	43/18670	0.004737	0.04123	0.03172	PRKCA/IL6ST/ROCK1/CAMK2D/EDN1/MIR19B2/PPP3CA/ROCK2/MIR214/PDE5A/MIR199A2/IGF1	12
BP	GO:0030866	cortical actin cytoskeleton organization	12/2306	43/18670	0.004737	0.04123	0.03172	ROCK1/RAB13/EPB41L3/FMNL2/CDK5/ARF6/TNF/EPB41L1/ROCK2/TLN1/PDCD6IP/EPB41L2	12
BP	GO:0050850	positive regulation of calcium-mediated signaling	12/2306	43/18670	0.004737	0.04123	0.03172	GSTO1/CALM1/PKD2/CCL3/LMCD1/ADA/P2RX3/TNF/CALM2/IGF1/HINT1/CHP2	12
BP	GO:0060612	adipose tissue development	12/2306	43/18670	0.004737	0.04123	0.03172	ID2/PPARGC1A/CSF1/ARID5B/FTO/ACAT1/LRP5/SIRT1/ARRDC3/SH3PXD2B/UBB/TBL1XR1	12
BP	GO:0046425	regulation of JAK-STAT cascade	28/2306	137/18670	0.00478	0.04154	0.03196	AKR1B1/CCL5/IL6/CSF2/LIF/PARP14/KIT/IL6ST/IL12A/SOCS1/SOCS3/CD40/FYN/IL26/IL15/GHR/F2R/CLCF1/PARP9/BCL3/CDK5/MIR19B2/HES5/TNF/SOCS2/IGF1/STAT3/ARL2BP	28
BP	GO:0032729	positive regulation of interferon-gamma production	16/2306	65/18670	0.004796	0.04163	0.03203	IL1B/RIPK2/IL12A/IL18R1/PDE4D/FADD/EBI3/BCL3/WNT5A/HAVCR2/TNF/IL12RB2/TLR3/ABL1/PDE4B/SASH3	16
BP	GO:0042129	regulation of T cell proliferation	31/2306	156/18670	0.004813	0.04171	0.03209	CCL5/IL6/CD70/VCAM1/IL1B/RIPK2/SH3RF1/IRF1/TNFSF9/CEBPB/TNFRSF14/PDCD1LG2/TNFRSF1B/IDO1/IL6ST/BMP4/TNFSF13B/HLA-E/IL12A/LRRC32/FADD/IL15/MAD1L1/EBI3/EFNB1/HAVCR2/HLA-G/SDC4/PDE5A/IGF1/SASH3	31
BP	GO:0051208	sequestering of calcium ion	27/2306	131/18670	0.004908	0.04248	0.03268	BDKRB1/CXCL10/FGF2/PLCE1/GSTO1/CALM1/PDE4D/CAMK2D/PKD2/CXCL11/CCL3/CYBA/UBASH3B/CXCL9/TRPC1/F2R/ITPR2/TPCN1/CALM2/MIR1-2/FKBP1A/DIAPH1/ABL1/MCOLN1/SRI/P2RX7/CASQ1	27
BP	GO:0006636	unsaturated fatty acid biosynthetic process	14/2306	54/18670	0.004933	0.04264	0.03281	PTGS2/IL1B/PTGES/ELOVL5/SCD/ELOVL7/EDN1/ELOVL2/ABCD1/SIRT1/DECR2/PTGS1/FADS3/ELOVL3	14
BP	GO:0002793	positive regulation of peptide secretion	51/2306	288/18670	0.004951	0.04273	0.03288	IL6/IL1B/RIPK2/IL33/KCNN4/ADORA2A/IL1A/IFIH1/IFNGR1/TNFRSF14/PANX1/GIP/HLA-E/IL4R/CD58/DDX58/IL26/PANX2/CCL3/IL17RB/GLUD1/AKAP12/GSDMD/TCF7L2/MBP/MYOM1/F2R/CCL1/TGFB2/PPIA/WNT5A/ADORA1/VPS35/MYO18A/ARF6/ARF1/ABAT/HAVCR2/TNF/SYTL4/DYNLL1/TRIM6/GATA3/ABL1/FERMT1/ATP13A2/IGF1/MYH10/SRI/P2RX7/ADAM8	51
BP	GO:0035456	response to interferon-beta	9/2306	28/18670	0.00504	0.04338	0.03338	IRF1/IFNAR2/IFITM1/PLSCR1/XAF1/STAT1/TLR3/TRIM6/CAPN2	9
BP	GO:2000108	positive regulation of leukocyte apoptotic process	9/2306	28/18670	0.00504	0.04338	0.03338	CCL5/PIK3CD/IDO1/FNIP1/MEF2C/SIRT1/WNT5A/P2RX7/ADAM8	9
BP	GO:0001914	regulation of T cell mediated cytotoxicity	10/2306	33/18670	0.005094	0.04372	0.03364	IL7R/HLA-E/IL12A/HLA-F/FADD/HLA-A/HLA-G/P2RX7/HLA-B/HLA-H	10
BP	GO:0002756	MyD88-independent toll-like receptor signaling pathway	10/2306	33/18670	0.005094	0.04372	0.03364	BIRC3/BIRC2/TNIP3/IRF7/TRAF3/FADD/RAB11FIP2/TLR3/UBB/TICAM1	10
BP	GO:0072330	monocarboxylic acid biosynthetic process	59/2306	343/18670	0.005115	0.04384	0.03373	PTGS2/CH25H/IL1B/PTGES/PPARGC1A/ACOX2/SLC2A6/INSIG2/IDO1/OSBPL1A/ALDH1A3/HK2/GIP/ACACB/ELOVL5/ENO2/ADPGK/RDH10/NUP133/VCAN/SCD/ELOVL7/PGM2L1/TRIB3/EDN1/LIPG/ACACA/AMACR/CYP1A2/CBR4/ADIPOR2/ELOVL2/ABCD1/NDUFAB1/SIRT1/OSBPL3/RGN/HSD17B12/DECR2/HSD3B7/ABAT/ASNS/ABHD3/PRKAB2/PGAM4/ACOT8/PECR/SCP2/PTGS1/NUP35/IGF1/STAT3/ALDOC/P2RX7/MID1IP1/FADS3/SIRT6/OSBPL7/ELOVL3	59
BP	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	40/2306	215/18670	0.005122	0.04384	0.03373	BIRC3/BID/PTGS2/SH3RF1/ADORA2A/BIRC2/PRR7/DAPK1/TNFAIP8/PDCD5/VEGFA/CFLAR/CD44/HERPUD1/FAS/ARL6IP5/KLF4/MTCH1/FADD/THBS1/CRYAB/FNIP1/PMAIP1/F2R/MMP9/ROBO1/SIRT1/TRAF2/NKX3-1/TP63/GSN/TNF/SOX7/TNFRSF10B/MAGEA3/BCL10/GAS6/PPARG/FAM162A/ST20	40
BP	GO:1902107	positive regulation of leukocyte differentiation	29/2306	144/18670	0.005146	0.04398	0.03384	NFKBIZ/LIF/CD83/RIPK2/ID2/TRIB1/CSF1/TNFSF9/IL7R/PRKCA/IL12A/MYB/IL4R/SOCS1/FADD/IL15/CYLD/ADA/TMEM64/ACIN1/AXL/TNF/GATA3/HLA-G/DUSP10/GAS6/SASH3/ADAM8/CBFB	29
BP	GO:0046620	regulation of organ growth	24/2306	113/18670	0.005223	0.04459	0.0343	BASP1/FGF2/MEIS1/JARID2/DUSP6/PAK1/ACACB/WWC1/LATS2/PIM1/STK4/EDN1/RGS2/GATA6/YAP1/CARM1/MEF2C/MIR19B2/RGS4/MIR1-2/MYH6/MIR199A2/IGF1/SASH3	24
BP	GO:0050678	regulation of epithelial cell proliferation	64/2306	378/18670	0.005286	0.04503	0.03464	BMP2/TNFAIP3/CCL5/CCL2/CDK6/FGF2/PRKCA/SIX1/MCC/STAT1/VEGFA/EREG/CFLAR/BMP4/LAMB1/NR2F2/BMPR2/CCND1/IL26/LIMS2/ITGA4/CYBA/THBS1/ZFP36/SULF2/TCF7L2/TGFA/TGFB2/ERRFI1/SNAI2/YAP1/HAS2/GDF5/SIX4/ROBO1/MEF2C/VDR/SIRT1/WNT5A/NKX3-1/SULF1/RGN/TP63/HES5/CDKN1C/TNF/PGF/SPARC/TACSTD2/OSR2/PTPRM/GATA3/RTN4/DUSP10/PPARG/FGF10/IGF1/AGGF1/STAT3/OSR1/FZD7/SIRT6/ATOH8/NFIB	64
BP	GO:2000106	regulation of leukocyte apoptotic process	19/2306	83/18670	0.00529	0.04503	0.03464	CCL5/PIK3CD/IL7R/IDO1/SLC7A11/BMP4/IRF7/FADD/SLC39A10/ADA/FNIP1/AXL/MEF2C/SIRT1/WNT5A/BCL10/GAS6/P2RX7/ADAM8	19
BP	GO:0034504	protein localization to nucleus	47/2306	262/18670	0.005298	0.04504	0.03465	NFKBIA/ZC3H12A/PTGS2/LIF/RAB23/SIX1/GBP2/LZTS2/BMP4/COL1A1/FYN/NUP133/LMNA/TRIM29/PIK3R2/UBR5/CARD10/ARNTL/KPNA3/PARP9/SIX4/BCL3/CDK5/RPAIN/SESN2/TXN/APPL2/TOPORS/SP100/PRKCD/NOL8/PPP3CA/NXT1/PKIG/TOR1A/CDKN1A/KPNA2/RANBP17/NUP35/FERMT1/CBLB/STAT3/DVL1/ARL2BP/DCLK2/CHP2/MORC3	47
BP	GO:0097193	intrinsic apoptotic signaling pathway	51/2306	289/18670	0.005308	0.04506	0.03467	SOD2/BID/PTGS2/BDKRB2/ERN1/HSPB1/CEBPB/TNFRSF1B/PPP1R15A/DNAJA1/PPIF/PLEKHF1/BCL2L2/CD44/HERPUD1/ARL6IP5/TMEM117/FNIP2/BCLAF1/DYRK2/CYLD/TRIB3/E2F2/PMAIP1/HIPK2/GRINA/NME5/SNAI2/MMP9/POLB/BCL3/SIRT1/TRAF2/NKX3-1/BCL2L1/TP63/PRKRA/DDX5/TNF/TOPORS/HYOU1/BRSK2/TNFRSF10B/IVNS1ABP/MAGEA3/PRKCD/ABL1/UBB/CDKN1A/MYBBP1A/HINT1	51
BP	GO:0051651	maintenance of location in cell	21/2306	95/18670	0.005362	0.04545	0.03497	DBN1/HK2/FTH1/ANK3/GPSM2/EPB41L3/FLNB/BCL3/CDK5/SRGN/TXN/GSN/TOPORS/SP100/ARHGAP21/FTHL17/ARL2BP/SRI/TLN1/RER1/MORC3	21
BP	GO:0006816	calcium ion transport	72/2306	434/18670	0.005383	0.04557	0.03506	ICAM1/BDKRB1/CCL5/PTGS2/CXCL10/KCNN4/CCL2/CCL8/ADORA2A/FGF2/PLCE1/PANX1/PDGFRB/GSTO1/RRAD/FYN/CALM1/PDE4D/CAMK2D/PKD2/CXCL11/CCL3/CYBA/SLC3A2/UBASH3B/CACHD1/CYP27B1/CXCL9/THADA/TRPC1/F2R/GJC2/ITPR2/GEM/VDR/CDK5/STAC/RGS4/TPCN1/RGN/RAMP1/SLC30A1/MYLK/P2RX3/CACNA1F/PARL/CACNA1B/CAMK2G/CALM2/ATP2A2/MIR1-2/STIM1/FKBP1A/SPINK1/DIAPH1/PPP3CA/GRIN3A/ABL1/PDE4B/VDAC1/ORAI1/GAS6/MCOLN1/NPPA/NMUR2/SRI/P2RX7/CLCA1/CASQ1/HOMER2/TMEM165/ADRA2A	72
BP	GO:0043491	protein kinase B signaling	48/2306	269/18670	0.005405	0.0457	0.03516	CCL5/IL1B/CCL2/KIT/FGF2/C1QTNF1/PIK3CD/EREG/PDGFRB/CD40/FYN/IRS1/IL26/KLF4/CCL3/THBS1/PIK3R2/TRIB3/TCF7L2/TGFA/HBEGF/MC1R/PIK3R3/SESN3/AXL/SIRT1/TNFAIP8L3/RCN3/NKX3-1/GDF15/SESN2/TXN/MIR137/TNF/FGF5/PEAR1/IAPP/GATA3/HLA-G/RTN4/PPP2R5C/GAS6/PTPN11/ENG/FGF10/MIR199A2/IGF1/ADAM8	48
BP	GO:0002685	regulation of leukocyte migration	37/2306	196/18670	0.00542	0.04576	0.03521	CCL20/ICAM1/BDKRB1/CCL5/IL6/CXCL10/IL33/CCL2/CCL8/CSF1/CCL7/TNFRSF14/VEGFA/JAM3/IL12A/CMKLR1/SLIT2/CCL3/FADD/ITGA4/THBS1/ADA/EDN1/PDGFD/CCL1/ITGA2/AKIRIN1/WNT5A/ADORA1/TNF/PGF/SLAMF8/SERPINE1/GAS6/ADAM8/CYP19A1/CRKL	37
BP	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	35/2306	183/18670	0.005432	0.04579	0.03523	BIRC3/IL1B/RIPK2/BIRC2/IRAK4/PLK2/CFLAR/TSPAN6/TRIM25/CD40/FYN/PIM2/TIFA/TRAF3IP2/FADD/NDFIP1/ROR1/F2R/CXXC5/LPAR1/TRAF2/TNF/TNFRSF10B/FKBP1A/UBD/TLR3/NEK6/ABL1/RBCK1/BCL10/NDFIP2/TICAM1/TRIM38/TMEM101/PELI2	35
BP	GO:0046626	regulation of insulin receptor signaling pathway	16/2306	66/18670	0.005621	0.04714	0.03627	PID1/IL1B/PTPRE/PAK1/SOCS1/SOCS3/IRS1/GRB14/ENPP1/SESN3/SIRT1/SOCS2/PRKCD/NUCKS1/PTPN11/NCOA5	16
BP	GO:1901607	alpha-amino acid biosynthetic process	16/2306	66/18670	0.005621	0.04714	0.03627	GLS/MTHFD2L/PSPH/GLUD1/SEPHS1/PSAT1/PLOD2/GAMT/MTR/ASS1/BHMT2/ASNS/PHGDH/MTAP/CPS1/BCAT2	16
BP	GO:0030278	regulation of ossification	38/2306	203/18670	0.00563	0.04714	0.03627	BMP2/IL6/ID2/CDK6/CEBPD/CSF1/CEBPB/ISG15/IFITM1/IL6ST/BMP4/BMPR2/CCL3/DHRS3/MSX2/CYP27B1/ENPP1/SEMA4D/TGFB2/TMEM64/SNAI2/LRP5/MEF2C/SRGN/WNT5A/TP63/RANBP3L/DDX5/TNF/BGLAP/BMP2K/OSR2/CEBPA/ID3/IGF1/OSR1/ZHX3/P2RX7	38
BP	GO:1903311	regulation of mRNA metabolic process	56/2306	324/18670	0.005656	0.04714	0.03627	ZC3H12A/PSME2/WTAP/PSMA6/HSPB1/PSMB10/MBNL1/PSMB8/PRKCA/PSMB7/PSME1/YTHDC1/FAM172A/RNF20/ROCK1/PSMB9/SET/MOV10/FTO/PSMA3/ZFP36/EXOSC6/ZFP36L2/CSDC2/SON/HNRNPA0/SRPK3/PDE12/DCP1A/RBM17/PSMA1/CPSF6/C9orf78/PSMB2/PABPC1/BTG2/SERBP1/SAMD4B/PSMB3/DDX5/SLTM/RBM15/CNOT8/MBNL2/SYNCRIP/PRKCD/IWS1/PSMA8/FASTKD3/ROCK2/FXR2/UBB/ANGEL2/PSME4/PSMB5/PSMF1	56
BP	GO:0002726	positive regulation of T cell cytokine production	7/2306	19/18670	0.005668	0.04714	0.03627	IL6/IL1B/RSAD2/IL18R1/TRAF2/GATA3/SASH3	7
BP	GO:0034138	toll-like receptor 3 signaling pathway	7/2306	19/18670	0.005668	0.04714	0.03627	TNFAIP3/FADD/FLOT1/WDFY1/HAVCR2/TLR3/TICAM1	7
BP	GO:0071243	cellular response to arsenic-containing substance	7/2306	19/18670	0.005668	0.04714	0.03627	ZC3H12A/DAXX/GSTO1/PPIF/MKNK2/MAPK13/ZFAND2A	7
BP	GO:0071800	podosome assembly	7/2306	19/18670	0.005668	0.04714	0.03627	CSF2/FSCN1/ARHGEF5/GSN/TNF/SH3PXD2B/ASAP1	7
BP	GO:1902170	cellular response to reactive nitrogen species	7/2306	19/18670	0.005668	0.04714	0.03627	MMP3/PPARGC1A/FOXO1/CFLAR/STAT6/TRAF2/MTR	7
BP	GO:2000696	regulation of epithelial cell differentiation involved in kidney development	7/2306	19/18670	0.005668	0.04714	0.03627	LIF/STAT1/WWTR1/YAP1/MMP9/GATA3/OSR1	7
BP	GO:0032965	regulation of collagen biosynthetic process	12/2306	44/18670	0.005795	0.04807	0.03698	IL6/BMP4/PDGFRB/MYB/F2R/ITGA2/ERRFI1/CYGB/PPARG/ENG/MIR218-1/SERPINF2	12
BP	GO:0035850	epithelial cell differentiation involved in kidney development	12/2306	44/18670	0.005795	0.04807	0.03698	LIF/BASP1/STAT1/BMP4/WWTR1/MYO1E/PODXL/YAP1/MMP9/MEF2C/GATA3/OSR1	12
BP	GO:0061180	mammary gland epithelium development	17/2306	72/18670	0.005836	0.04834	0.03719	ID2/CSF1/NTN1/CEBPB/CCND1/MSX2/LBH/STAT6/LRP5/ROBO1/VDR/WNT5A/GATA3/RTN4/ORAI1/FGF10/TBX3	17
BP	GO:0030218	erythrocyte differentiation	24/2306	114/18670	0.00586	0.04839	0.03723	SLC11A2/ID2/CDK6/KIT/ISG15/MAFB/EPAS1/STAT1/VEGFA/BMP4/KLF2/ETS1/NFE2L1/ADAR/ZFP36/PRMT1/HIPK2/ERCC2/KLF13/THRA/ACIN1/GATA3/STAT3/ARID4A	24
BP	GO:0046546	development of primary male sexual characteristics	28/2306	139/18670	0.005881	0.04839	0.03723	ICAM1/CITED2/KIT/ARID5B/RAB13/PDGFRB/BCL2L2/CCND1/HOXA11/HOXA10/SRD5A1/LHFPL2/TGFB2/GATA6/NUDT1/RHOBTB3/SIX4/WNT5A/NKX3-1/BCL2L1/MAMLD1/HOXA9/TLR3/GATA3/EIF2S2/UBB/CRKL/ARID4A	28
BP	GO:0050715	positive regulation of cytokine secretion	28/2306	139/18670	0.005881	0.04839	0.03723	IL1B/RIPK2/IL33/IL1A/IFIH1/IFNGR1/TNFRSF14/PANX1/IL4R/CD58/DDX58/IL26/PANX2/CCL3/IL17RB/AKAP12/GSDMD/MBP/F2R/CCL1/WNT5A/HAVCR2/TNF/TRIM6/GATA3/ABL1/FERMT1/P2RX7	28
BP	GO:0051588	regulation of neurotransmitter transport	28/2306	139/18670	0.005881	0.04839	0.03723	ADORA2A/PNKD/ARL6IP5/BACE1/SNX4/RAB3GAP1/RGS2/FLOT1/MEF2C/CDK5/RGS4/RAB3A/SYT4/PREPL/PFN2/SLC30A1/ABAT/DGKI/ATP2A2/STXBP1/SYT1/GRIN3A/TOR1A/VAMP7/NPPA/NAPB/DVL1/P2RX7	28
BP	GO:0070665	positive regulation of leukocyte proliferation	28/2306	139/18670	0.005881	0.04839	0.03723	CCL5/IL6/CD70/VCAM1/IL1B/RIPK2/CSF1/TNFSF9/PDCD1LG2/IL6ST/TNFSF13B/HLA-E/IL12A/CD40/FADD/SLC39A10/IL15/ADA/EBI3/CLCF1/EFNB1/MEF2C/HAVCR2/CDKN1A/FGF10/TICAM1/IGF1/SASH3	28
BP	GO:1904018	positive regulation of vasculature development	42/2306	230/18670	0.005892	0.04842	0.03726	SOD2/ZC3H12A/PTGS2/IL1B/HSPB1/IL1A/KIT/FGF2/DDAH1/PRKCA/C3/VEGFA/HK2/PLK2/CFLAR/CD40/RHOJ/ETS1/KLF4/THBS1/BMPER/ADM2/HIPK2/PDGFD/RHOB/ITGB8/GATA6/SIRT1/WNT5A/PGF/MIR1-2/MIR125B1/STIM1/TLR3/SERPINE1/ABL1/EPHA1/ENG/MIR199A2/AGGF1/STAT3/SIRT6	42
BP	GO:1990778	protein localization to cell periphery	54/2306	311/18670	0.005912	0.04852	0.03733	PID1/DAB2/SQSTM1/ZFYVE27/ROCK1/RAB13/NKD2/PPFIA1/GPC4/PLEKHF1/SYS1/MYADM/STX3/ANK3/GBP1/RDX/CLTC/GPSM2/EPB41L3/RAB11FIP2/LIN7A/BBS2/FLOT1/CLIP3/PPIL2/EFR3A/CDK5/STAC/OPTN/KCNB1/SNAP47/VPS35/RAB3A/ARF6/BCL2L1/RAMP1/PREPL/MRAP2/ACTB/TNF/STXBP1/ROCK2/GAS6/VAMP7/PACS2/RILPL1/LIN7C/RAB31/GRIPAP1/KCNB2/RER1/PICALM/VAMP5/EPB41L2	54
BP	GO:0000271	polysaccharide biosynthetic process	18/2306	78/18670	0.005979	0.04901	0.03771	NFKB1/PPP1R3F/UGP2/IRS1/PGM2L1/DYRK2/ENPP1/CLTC/CSGALNACT1/HAS2/CSGALNACT2/HAS1/GYG1/HAS3/GYS2/EXT1/HS2ST1/IGF1	18
BP	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	22/2306	102/18670	0.006036	0.04928	0.03791	TNFAIP3/NR2F2/LATS2/PKD2/CCND1/CDC25A/CCNO/SERTAD1/KAT2B/HEXIM2/CCNG2/CDKN2C/CDKN1C/CCNYL1/ACTB/CCNG1/HERC5/CEBPA/CCNJL/CDKN1A/MNAT1/CDK7	22
BP	GO:0001823	mesonephros development	22/2306	102/18670	0.006036	0.04928	0.03791	BMP2/BASP1/FGF2/SIX1/VEGFA/LZTS2/BMP4/SLIT2/PKD2/HOXA11/BMPER/SPRY1/SIX4/PGF/TACSTD2/OSR2/GATA3/HOXB7/SDC4/LGR4/FGF10/OSR1	22
BP	GO:2000379	positive regulation of reactive oxygen species metabolic process	22/2306	102/18670	0.006036	0.04928	0.03791	ZC3H12A/ICAM1/PTGS2/PID1/IL1B/DDAH1/KLF2/PDGFRB/PKD2/KLF4/CYBA/THBS1/EDN1/RGN/TNF/ASS1/DDAH2/PTX3/PRKCD/HBB/CDKN1A/TICAM1	22
BP	GO:0060420	regulation of heart growth	19/2306	84/18670	0.006062	0.04943	0.03803	BASP1/FGF2/MEIS1/JARID2/DUSP6/PAK1/ACACB/PIM1/EDN1/RGS2/GATA6/YAP1/MEF2C/MIR19B2/RGS4/MIR1-2/MYH6/MIR199A2/IGF1	19
BP	GO:0006835	dicarboxylic acid transport	21/2306	96/18670	0.006083	0.04946	0.03806	ADORA2A/GLS/SLC7A11/SLC38A2/PPFIA1/ARL6IP5/RAB3GAP1/LRRC8E/ABCC2/ADORA1/RAB3A/SYT4/ABAT/CLN8/STXBP1/GRM2/SYT1/SLC26A3/SLC19A1/P2RX7/PPFIA3	21
BP	GO:0098876	vesicle-mediated transport to the plasma membrane	21/2306	96/18670	0.006083	0.04946	0.03806	ANKRD50/SYS1/STX3/ANK3/MICALL1/BBS2/OPTN/SNAP47/VPS35/ARF1/PREPL/OSBPL5/ARF3/CCDC93/VAMP7/STEAP2/RAB31/GRIPAP1/ANKRD27/VPS26A/VAMP5	21
BP	GO:0071674	mononuclear cell migration	20/2306	90/18670	0.006094	0.04949	0.03808	CCL20/CCL5/IL6/CXCL10/CCL2/CCL8/CSF1/CCL7/CCL3L3/CMKLR1/SLIT2/CCL3/THBS1/PDGFD/SIRPA/CCL1/AKIRIN1/TNF/SLAMF8/SERPINE1	20
BP	GO:0035265	organ growth	38/2306	204/18670	0.006116	0.0496	0.03816	BASP1/FGF2/MEIS1/JARID2/DUSP6/PAK1/PDGFRB/ACACB/WWC1/RXRA/LATS2/PIM1/MSX2/SCARA3/STK4/EDN1/TGFB2/RGS2/GATA6/YAP1/BNC2/CARM1/MEF2C/MIR19B2/RGS4/COL6A3/PDLIM5/MIR1-2/RSPO2/PTPN11/MYH6/NPPA/FGF10/MIR199A2/IGF1/SASH3/CYP19A1/SIRT6	38
BP	GO:0010761	fibroblast migration	11/2306	39/18670	0.006165	0.04986	0.03836	FGF2/ARID5B/CORO1C/PAK1/THBS1/AKAP12/CYGB/GNA12/APPL2/HAS1/SDC4	11
BP	GO:0014741	negative regulation of muscle hypertrophy	11/2306	39/18670	0.006165	0.04986	0.03836	JARID2/TNFRSF1B/FOXO1/PAK1/LMNA/RGS2/ERRFI1/RGS4/MIR1-2/MIR214/MIR199A2	11
BP	GO:0003170	heart valve development	15/2306	61/18670	0.006271	0.05046	0.03882	BMP2/TNFRSF1B/ROCK1/BMP4/SLIT2/BMPR2/FGFRL1/TGFB2/HECTD1/SNAI2/ROBO1/MEF2C/GATA3/PRDM1/ROCK2	15
BP	GO:0032370	positive regulation of lipid transport	15/2306	61/18670	0.006271	0.05046	0.03882	NFKBIA/IL1B/ABCA1/C1QTNF1/MYB/FABP3/EDN1/LIPG/SIRT1/NKX3-1/ATP8A2/PRKCD/SCP2/P2RX7/CYP19A1	15
BP	GO:0048645	animal organ formation	15/2306	61/18670	0.006271	0.05046	0.03882	CITED2/SIX1/BMP4/RDH10/HOXA11/SMARCD3/PIM1/SPRY1/GATA6/ROBO1/MEF2C/WNT5A/SULF1/TP63/FGF10	15
BP	GO:1903902	positive regulation of viral life cycle	15/2306	61/18670	0.006271	0.05046	0.03882	CCL5/IFIT1/CHMP4B/ADAR/PPIA/PDE12/PABPC1/TRIM21/RAD23A/STAU1/ADARB1/NUCKS1/KPNA2/PKN2/TRIM38	15
BP	GO:1902410	mitotic cytokinetic process	8/2306	24/18670	0.006319	0.05071	0.03902	CHMP1B/CHMP4B/KLHDC8B/ARF1/BIN3/CHMP5/MITD1/PDCD6IP	8
BP	GO:1904376	negative regulation of protein localization to cell periphery	8/2306	24/18670	0.006319	0.05071	0.03902	PID1/DAB2/PPFIA1/GBP1/CLTC/BCL2L1/MRAP2/PICALM	8
BP	GO:0060485	mesenchyme development	49/2306	278/18670	0.006334	0.05077	0.03906	BMP2/IL6/IL1B/CITED2/DAB2/BASP1/PDPN/SIX1/STAT1/FAM172A/CORO1C/BMP4/PDGFRB/WWTR1/COL1A1/RDH10/NUP133/BMPR2/PKD2/MSX2/ACTC1/EDN1/SDCBP/SEMA4D/TGFB2/PHLDB1/SPRY1/SNAI2/YAP1/BNC2/HAS2/EFNB1/SIX4/ROBO1/MEF2C/PHLDB2/DACT3/WNT5A/RANBP3L/DDX5/PTK7/RTN4/ENG/FGF10/SEMA4F/OSR1/SDHAF2/AKNA/GLIPR2	49
BP	GO:0001558	regulation of cell growth	69/2306	416/18670	0.006363	0.05093	0.03919	BDKRB1/OSGIN2/NTN1/FHL1/ZFYVE27/PLCE1/DBN1/VEGFA/PAK1/RERG/NDRG3/SLIT2/CAMK2D/BMPR2/NET1/RUFY3/CYBA/ITCH/IL17RB/EDN1/CYP27B1/CRYAB/PPT1/HBEGF/SH3BP4/ENPP1/SDCBP/SEMA4D/EPB41L3/DCBLD2/PPP1R9B/TGFB2/RGS2/TCHP/ADIPOR2/SMARCA2/SERTAD2/IFRD1/CDKN2C/DACT3/CDK5/SIRT1/MIR19B2/WNT5A/RGS4/SYT4/SESN2/IGFBPL1/BAP1/SOCS2/GDI1/SYT1/RTN4/ABL1/ZNF639/SLC25A33/PPARG/CDKN1A/NPPA/ROS1/CDC42/SEMA4F/MIR199A2/IGF1/CDH4/TSPYL2/CRKL/SGK3/ST20	69
BP	GO:0097009	energy homeostasis	10/2306	34/18670	0.006432	0.0511	0.03931	PPARGC1A/FOXO1/ACACB/IRX3/AMPD3/SGIP1/MRAP2/UBB/STAT3/CRTC3	10
BP	GO:0001961	positive regulation of cytokine-mediated signaling pathway	13/2306	50/18670	0.006457	0.0511	0.03931	RIPK2/PARP14/CSF1/IRF7/FADD/EDN1/PARP9/AXL/WNT5A/TRAF2/TRIM6/GAS6/ZBP1	13
BP	GO:0009409	response to cold	13/2306	50/18670	0.006457	0.0511	0.03931	NFKBIA/CXCL10/PPARGC1A/FOXO1/NFE2L1/EIF2AK4/DNAJC3/THRA/TMEM135/LRP11/P2RX3/APPL2/PPARG	13
BP	GO:0010171	body morphogenesis	13/2306	50/18670	0.006457	0.0511	0.03931	ARID5B/GREM2/COL1A1/RAB3GAP1/ZNF281/PHLDB1/PHLDB2/CRISPLD2/CRISPLD1/PTPN11/ANKRD11/MAB21L2/SSBP3	13
BP	GO:0010718	positive regulation of epithelial to mesenchymal transition	13/2306	50/18670	0.006457	0.0511	0.03931	BMP2/IL6/IL1B/DAB2/PDPN/BMP4/WWTR1/COL1A1/TCF7L2/SDCBP/TGFB2/ENG/GLIPR2	13
BP	GO:0070741	response to interleukin-6	13/2306	50/18670	0.006457	0.0511	0.03931	ICAM1/IL6/PID1/NFKB1/PPARGC1A/STAT1/IL6ST/SOCS3/ABCC2/MIR125B1/CEBPA/PTPN11/STAT3	13
BP	GO:0046328	regulation of JNK cascade	35/2306	185/18670	0.006467	0.0511	0.03931	IL1B/RIPK2/SH3RF1/ERN1/TPD52L1/DAXX/ANKRD6/DNAJA1/PAK1/ITCH/CYLD/EDN1/SDCBP/HIPK2/SIRPA/DUSP3/GADD45G/FZD8/WNT5A/TRAF2/ARHGEF5/TNF/MAP3K2/MLKL/FZD4/TLR3/DUSP10/PER1/PJA2/SH3RF2/DVL2/SERPINF2/TAOK1/FZD7/ZNF675	35
BP	GO:0097553	calcium ion transmembrane import into cytosol	28/2306	140/18670	0.006506	0.0511	0.03931	BDKRB1/CXCL10/FGF2/PLCE1/GSTO1/FYN/CALM1/PDE4D/CAMK2D/PKD2/CXCL11/CCL3/CYBA/UBASH3B/CXCL9/TRPC1/F2R/ITPR2/TPCN1/CALM2/MIR1-2/FKBP1A/DIAPH1/ABL1/MCOLN1/SRI/P2RX7/CASQ1	28
BP	GO:0010644	cell communication by electrical coupling	9/2306	29/18670	0.006521	0.0511	0.03931	GJD3/DBN1/CALM1/PDE4D/CAMK2D/ANK3/GJC2/CALM2/SRI	9
BP	GO:0030258	lipid modification	43/2306	238/18670	0.006521	0.0511	0.03931	PPARGC1A/PIK3CD/ACOX2/ACACB/SOCS1/SOCS3/FABP3/HIBCH/IRS1/CROT/PIK3R2/ACAT1/HADH/ACAT2/CPT1A/PIK3R3/IMPA2/AMACR/ADIPOR2/SOAT1/CYGB/ABCD1/EFR3A/SESN2/ACAA2/DECR2/DGKI/APPL2/SOCS2/INPP5B/LONP2/BDH2/ACOT8/PECR/SCP2/PPARG/PIP4K2A/INPP1/PI4K2B/ACOXL/ACADM/SLC35C1/ST3GAL4	43
BP	GO:0002467	germinal center formation	6/2306	15/18670	0.00654	0.0511	0.03931	TNFAIP3/NFKB2/TNFSF13B/ADA/BCL3/MEF2C	6
BP	GO:0009109	coenzyme catabolic process	6/2306	15/18670	0.00654	0.0511	0.03931	CBR3/NUDT7/ACAT1/ABCD1/PDXP/ALDH1L2	6
BP	GO:0014856	skeletal muscle cell proliferation	6/2306	15/18670	0.00654	0.0511	0.03931	FGF2/SIX1/CFLAR/SIX5/AKIRIN1/STAT3	6
BP	GO:0042921	glucocorticoid receptor signaling pathway	6/2306	15/18670	0.00654	0.0511	0.03931	ARNTL/YWHAH/ARID1A/PER1/NEDD4/NCOA6	6
BP	GO:0045073	regulation of chemokine biosynthetic process	6/2306	15/18670	0.00654	0.0511	0.03931	IL6/IL1B/WNT5A/TNF/TLR3/TICAM1	6
BP	GO:0046851	negative regulation of bone remodeling	6/2306	15/18670	0.00654	0.0511	0.03931	TNFAIP3/IL6/UBASH3B/IAPP/TNFRSF11B/P2RX7	6
BP	GO:0051044	positive regulation of membrane protein ectodomain proteolysis	6/2306	15/18670	0.00654	0.0511	0.03931	IL1B/TNFRSF1B/SH3D19/TNF/ADAM8/ADRA2A	6
BP	GO:0071801	regulation of podosome assembly	6/2306	15/18670	0.00654	0.0511	0.03931	CSF2/FSCN1/ARHGEF5/GSN/TNF/ASAP1	6
BP	GO:0090177	establishment of planar polarity involved in neural tube closure	6/2306	15/18670	0.00654	0.0511	0.03931	FZD1/FZD2/WNT5A/PTK7/DVL1/DVL2	6
BP	GO:0010927	cellular component assembly involved in morphogenesis	24/2306	115/18670	0.006559	0.05118	0.03938	CFLAR/PDGFRB/CNTNAP1/ACTC1/EDN1/MYOM1/EPB41L3/ERCC2/PHLDB1/SIX4/MEF2C/PHLDB2/CCDC136/MYOM3/UGT8/MIR1-2/KRT19/ZPBP2/TMOD2/MYH6/MYH10/ACTG1/CASQ1/RFX2	24
BP	GO:0018105	peptidyl-serine phosphorylation	52/2306	299/18670	0.006595	0.05138	0.03953	PTGS2/IL6/LIF/RIPK2/BDKRB2/ERN1/CNKSR3/PRKCA/GPD1L/VEGFA/ROCK1/PLK2/PAK1/CD44/BCAR3/PDE4D/CAMK2D/LATS2/FNIP2/DYRK2/MKNK2/STK4/MAPK13/STK38L/DMPK/FNIP1/HIPK2/SMYD3/CSNK1G2/RPS6KA4/CSNK1E/CDK5/WNT5A/ARAF/MTCP1/PFN2/TXN/TNF/TLK1/BRSK2/NEK6/TRIM6/PRKCD/PDK3/ROCK2/GAS6/PKN2/CSNK1G3/MAST4/DCLK2/SGK3/MORC3	52
BP	GO:0031589	cell-substrate adhesion	60/2306	354/18670	0.006601	0.05138	0.03953	VCAM1/ITGA1/NINJ1/CDK6/CSF1/PDPN/CORO1C/VEGFA/ROCK1/JAM3/VCL/LAMB1/PPFIA1/COL1A1/PLAU/CD44/NEDD9/ITGB5/MYADM/LIMS2/VWF/HSPG2/MKLN1/GBP1/ITGA4/THBS1/TRIP6/PXN/CCDC80/ITGA2/RSU1/HAS2/DUSP3/AXL/NID2/PHLDB2/ARPC2/CDK5/ITGA11/HSD17B12/HOXD3/TACSTD2/ACTN4/FERMT2/FZD4/COL16A1/MEGF9/SDC4/ZYX/SERPINE1/ABL1/ROCK2/GAS6/EPHA1/CDC42/FERMT1/ITGA6/ITGBL1/FZD7/CRKL	60
BP	GO:0007565	female pregnancy	36/2306	192/18670	0.006723	0.05214	0.04011	AKR1B1/NAMPT/PTGS2/IL1B/LIF/RECK/SLC2A1/IDO1/GIP/SLC38A2/RXRA/ETS1/NR2F2/BMPR2/OXTR/CYP27B1/PTHLH/ADCY7/RGS2/ITGA2/LDOC1/GJB2/ADIPOR2/MMP9/VDR/JUNB/ABCC2/HAVCR2/PGF/COL16A1/PAPPA/ARID1A/PRDM1/ARHGDIB/NPPA/CAPN2	36
BP	GO:0006766	vitamin metabolic process	27/2306	134/18670	0.006724	0.05214	0.04011	CBR3/IL1B/NFKB1/KYNU/SLC2A1/MTHFD2L/GSTO1/RDH10/RXRA/CYP27B1/MTHFD2/SLC19A3/ENPP1/PNPO/PSAT1/ABCC1/SNAI2/CYB5A/UBIAD1/VDR/RGN/MTR/TNF/PDXP/SLC19A1/ALDH1L2/MMADHC	27
BP	GO:0046683	response to organophosphorus	27/2306	134/18670	0.006724	0.05214	0.04011	PTGS2/IL1B/BIRC2/AHR/STAT1/AQP9/PANX1/EEF2K/COL1A1/P2RY11/PKD2/SSH1/SRD5A1/LPAR1/NDUFS4/CARM1/HCN4/ITPR2/JUNB/P2RX3/ASS1/SPARC/CPS1/PDXP/PER1/SLC26A3/P2RX7	27
BP	GO:2001235	positive regulation of apoptotic signaling pathway	34/2306	179/18670	0.006766	0.0524	0.04031	BID/PPP3CC/ADORA2A/TPD52L1/PRR7/G0S2/PDCD5/PPP2R1B/PPIF/PLEKHF1/FAS/BCLAF1/FADD/THBS1/CYLD/STK4/INHBB/PMAIP1/MMP9/DEDD2/SIRT1/TRAF2/NKX3-1/BCL2L1/TP63/PRKRA/GSN/YWHAH/PRKCD/RBCK1/BCL10/UBB/TFDP1/FAM162A	34
BP	GO:0015908	fatty acid transport	21/2306	97/18670	0.006882	0.05291	0.04071	IL1B/BDKRB2/SLC27A3/PLA2G4A/PLIN2/ACACB/FABP3/THBS1/CROT/EDN1/CPT1A/ACACA/ABCD1/PLA2G12A/ABCC2/SLC25A20/PRKAB2/PPARG/NMUR2/P2RX7/MID1IP1	21
BP	GO:0014909	smooth muscle cell migration	20/2306	91/18670	0.006926	0.05291	0.04071	CCL5/TRIB1/PPARGC1A/PAK1/PDGFRB/PLAU/SLIT2/SSH1/PDGFD/ITGA2/LPAR1/HAS2/MEF2C/MIR137/DOCK4/SERPINE1/MIR214/IGF1/MIR218-1/FOXO4	20
BP	GO:1904063	negative regulation of cation transmembrane transport	20/2306	91/18670	0.006926	0.05291	0.04071	GSTO1/RRAD/PPIF/CALM1/CAMK2D/PKD2/ANK3/THADA/RGS2/HECW2/MMP9/GEM/RGS4/SLC30A1/CALM2/MIR1-2/OSR1/SRI/NEDD4/ADRA2A	20
BP	GO:0007599	hemostasis	58/2306	341/18670	0.006942	0.05291	0.04071	MAFF/IL6/SERPINB2/ADORA2A/HSPB1/IRF1/C1QTNF1/PRKCA/PDPN/PLSCR1/PF4V1/SLC7A11/VCL/COL1A1/PLAU/CD40/FYN/VWF/THBS1/MAFG/ANXA8/UBASH3B/EDN1/F2R/ITGA2/GATA6/GNA13/GNA12/EHD1/AXL/ITPR2/FLI1/CAPZA2/ABAT/DGKI/P2RX3/ACTB/STXBP1/PEAR1/GATA3/PRKCD/SERPINE1/COL1A2/HBB/GAS6/PTPN11/CDC42/SH2B1/MYH9/ACTG1/P2RX7/SERPINA1/SERPINF2/TLN1/MYL12A/ADRA2A/VPS45/GNG2	58
BP	GO:0001778	plasma membrane repair	5/2306	11/18670	0.006943	0.05291	0.04071	MYOF/RAB3A/SYTL4/MYH9/MYH10	5
BP	GO:0010172	embryonic body morphogenesis	5/2306	11/18670	0.006943	0.05291	0.04071	GREM2/ZNF281/PHLDB1/PHLDB2/MAB21L2	5
BP	GO:0032060	bleb assembly	5/2306	11/18670	0.006943	0.05291	0.04071	ROCK1/LPAR1/EMP1/MYLK/P2RX7	5
BP	GO:0035747	natural killer cell chemotaxis	5/2306	11/18670	0.006943	0.05291	0.04071	CCL5/CCL2/CCL7/PIK3CD/CCL3	5
BP	GO:0046185	aldehyde catabolic process	5/2306	11/18670	0.006943	0.05291	0.04071	PNKD/ADH5/HAGH/ESD/PDXP	5
BP	GO:0055091	phospholipid homeostasis	5/2306	11/18670	0.006943	0.05291	0.04071	ABCA1/FABP3/LIPG/TLCD1/RCN3	5
BP	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity	5/2306	11/18670	0.006943	0.05291	0.04071	GSTO1/CALM1/PKD2/CALM2/SRI	5
BP	GO:0070106	interleukin-27-mediated signaling pathway	5/2306	11/18670	0.006943	0.05291	0.04071	STAT1/IL6ST/EBI3/TYK2/STAT3	5
BP	GO:0071803	positive regulation of podosome assembly	5/2306	11/18670	0.006943	0.05291	0.04071	CSF2/FSCN1/ARHGEF5/TNF/ASAP1	5
BP	GO:1902743	regulation of lamellipodium organization	12/2306	45/18670	0.007032	0.05352	0.04118	FSCN1/PDPN/CORO1C/AUTS2/CD44/SLIT2/AKIRIN1/ARPC2/BIN3/MIR214/CDC42/WASF2	12
BP	GO:0050709	negative regulation of protein secretion	28/2306	141/18670	0.007186	0.05462	0.04202	ZC3H12A/TNFAIP3/IL1B/IL33/RSAD2/LRRC32/IRS1/GBP1/RHBDF2/HADH/INHBB/F2R/SERGEF/SRGN/KCNB1/ANXA4/SYT4/TNF/SYTL4/SERPINB1/PPP3CA/LGR4/RAB11FIP1/GAS6/PTPN11/PYDC2/MAPKBP1/ADRA2A	28
BP	GO:0032623	interleukin-2 production	15/2306	62/18670	0.007349	0.05573	0.04288	TNFAIP3/IL1B/CD83/RIPK2/IL1A/PDE4D/GBP1/ZFP36/TRAF2/HAVCR2/GATA3/ABL1/PDE4B/SASH3/HOMER2	15
BP	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	15/2306	62/18670	0.007349	0.05573	0.04288	ERN1/CEBPB/PPP1R15A/HERPUD1/TMEM117/TRIB3/PMAIP1/GRINA/SIRT1/TRAF2/BCL2L1/HYOU1/BRSK2/TNFRSF10B/MAGEA3	15
BP	GO:0050817	coagulation	58/2306	342/18670	0.007379	0.05582	0.04295	MAFF/IL6/SERPINB2/ADORA2A/HSPB1/IRF1/C1QTNF1/PRKCA/PDPN/PLSCR1/PF4V1/SLC7A11/VCL/COL1A1/PLAU/CD40/FYN/VWF/THBS1/MAFG/ANXA8/UBASH3B/EDN1/F2R/ITGA2/GATA6/GNA13/GNA12/EHD1/AXL/ITPR2/MIR19B2/CAPZA2/ABAT/DGKI/P2RX3/ACTB/STXBP1/PEAR1/GATA3/PRKCD/SERPINE1/COL1A2/HBB/GAS6/PTPN11/CDC42/SH2B1/MYH9/ACTG1/P2RX7/SERPINA1/SERPINF2/TLN1/MYL12A/ADRA2A/VPS45/GNG2	58
BP	GO:0035051	cardiocyte differentiation	32/2306	167/18670	0.007389	0.05582	0.04295	BMP2/VCAM1/VEGFA/BMP4/PAK1/PDGFRB/RXRA/LMNA/ACTC1/EDN1/MYOM1/SGCD/TGFB2/RGS2/SPRY1/GATA6/MEF2C/MIR19B2/RGS4/MYOM3/PDLIM5/MIR1-2/ARID1A/MYH6/NPPA/SIK1/MIR199A2/IGF1/MYH10/FZD7/SGCB/TBX3	32
BP	GO:1901568	fatty acid derivative metabolic process	32/2306	167/18670	0.007389	0.05582	0.04295	PTGS2/IL1B/PTGES/PLA2G4A/ELOVL5/PLA2G4C/CYP2U1/SCD/ELOVL7/ACAT1/EDN1/PPT1/ACACA/PRG3/ACSL5/CYP1A2/ABCC1/CBR4/ELOVL2/ABCD1/DAGLA/SIRT1/HSD17B12/DAGLB/BDH2/FAR1/PTGS1/MGST2/FAAH2/CYP2C19/CYP2S1/ELOVL3	32
BP	GO:0048738	cardiac muscle tissue development	42/2306	233/18670	0.007401	0.05585	0.04297	BMP2/ID2/FGF2/MEIS1/JARID2/VEGFA/BMP4/PAK1/PDGFRB/RXRA/LMNA/PIM1/ACTC1/EDN1/MYOM1/SGCD/TGFB2/RGS2/GATA6/YAP1/MEF2C/MIR19B2/WNT5A/RGS4/MYOM3/PDLIM5/SGCG/MIR1-2/FKBP1A/ARID1A/MYH6/ENG/NPPA/SIK1/UBE4B/MIR199A2/IGF1/MYH10/FZD7/SGCB/SIRT6/TBX3	42
BP	GO:0050921	positive regulation of chemotaxis	27/2306	135/18670	0.007441	0.05608	0.04315	CCL5/IL6/CXCL10/HSPB1/CSF1/CCL7/FGF2/VEGFA/PDGFRB/IL12A/CMKLR1/SLIT2/BMPR2/STX3/CCL3/THBS1/EDN1/PDGFD/CCL1/ITGA2/LPAR1/AKIRIN1/WNT5A/PGF/SERPINE1/GAS6/FGF10	27
BP	GO:0010769	regulation of cell morphogenesis involved in differentiation	52/2306	301/18670	0.00752	0.05661	0.04355	ZSWIM4/NTN1/PDPN/ZFYVE27/SIPA1L1/DBN1/CAPRIN1/CORO1C/VEGFA/EEF2K/PAK1/NEDD9/SLIT2/BMPR2/MYADM/LIMS2/RUFY3/GBP1/NEUROG3/SEMA4D/SDC2/CHN1/HECW2/HAS2/IFRD1/ROBO1/ITPKA/ARPC2/CDK5/WNT5A/BHLHB9/PDLIM5/YWHAH/TACSTD2/BRSK2/ACTN4/PLXND1/GDI1/RTN4/PPP3CA/ABL1/YTHDF1/VAMP7/ACTR2/CDC42/SEMA4F/CDH4/MYCBP2/NEDD4/NGEF/ANKRD27/CRKL	52
BP	GO:0033866	nucleoside bisphosphate biosynthetic process	16/2306	68/18670	0.007614	0.0571	0.04393	ACACB/ELOVL5/SCD/ELOVL7/ACAT1/PPT1/ACACA/ACSL5/CBR4/ELOVL2/PPCS/HSD17B12/PDHB/PAPSS1/PDK3/ELOVL3	16
BP	GO:0034030	ribonucleoside bisphosphate biosynthetic process	16/2306	68/18670	0.007614	0.0571	0.04393	ACACB/ELOVL5/SCD/ELOVL7/ACAT1/PPT1/ACACA/ACSL5/CBR4/ELOVL2/PPCS/HSD17B12/PDHB/PAPSS1/PDK3/ELOVL3	16
BP	GO:0034033	purine nucleoside bisphosphate biosynthetic process	16/2306	68/18670	0.007614	0.0571	0.04393	ACACB/ELOVL5/SCD/ELOVL7/ACAT1/PPT1/ACACA/ACSL5/CBR4/ELOVL2/PPCS/HSD17B12/PDHB/PAPSS1/PDK3/ELOVL3	16
BP	GO:0071887	leukocyte apoptotic process	22/2306	104/18670	0.007645	0.05727	0.04406	CCL5/IL6/PIK3CD/IL7R/IDO1/SLC7A11/BMP4/IRF7/TRAF3IP2/FADD/SLC39A10/ADA/FNIP1/AXL/MEF2C/SIRT1/WNT5A/BCL10/GAS6/P2RX7/ADAM8/CRKL	22
BP	GO:0048146	positive regulation of fibroblast proliferation	13/2306	51/18670	0.007708	0.0576	0.04432	CDK6/EREG/PDGFRB/MYB/PDGFD/NDUFS4/WNT5A/PDGFC/GAS6/CDKN1A/FGF10/IGF1/SIRT6	13
BP	GO:0097366	response to bronchodilator	13/2306	51/18670	0.007708	0.0576	0.04432	ICAM1/ADORA2A/MMP3/FOXO1/CFLAR/OXTR/EGLN1/RGS2/RGS4/TRAF2/MTR/CNR2/PPP3CA	13
BP	GO:0001894	tissue homeostasis	41/2306	227/18670	0.007796	0.05797	0.0446	AKR1B1/TNFAIP3/IL6/HSPB1/CSF1/PRKCA/EPAS1/VEGFA/TP53INP2/WWTR1/LDB2/LIPA/CHMP4B/UBASH3B/CYTL1/F2R/ACACA/TMEM64/FH/BBS2/YAP1/RCN3/ACTB/BGLAP/CLN8/IAPP/ZNF830/PCDH15/PTPN11/ANKRD11/TNFRSF11B/SERPINA3/ACTG1/P2RX7/SASH3/ADAM8/HOMER2/ZNF675/TFF1/POTEF/SNX10	41
BP	GO:0007596	blood coagulation	57/2306	336/18670	0.007803	0.05797	0.0446	MAFF/IL6/SERPINB2/ADORA2A/HSPB1/IRF1/C1QTNF1/PRKCA/PDPN/PLSCR1/PF4V1/SLC7A11/VCL/COL1A1/PLAU/CD40/FYN/VWF/THBS1/MAFG/ANXA8/UBASH3B/EDN1/F2R/ITGA2/GATA6/GNA13/GNA12/EHD1/AXL/ITPR2/CAPZA2/ABAT/DGKI/P2RX3/ACTB/STXBP1/PEAR1/GATA3/PRKCD/SERPINE1/COL1A2/HBB/GAS6/PTPN11/CDC42/SH2B1/MYH9/ACTG1/P2RX7/SERPINA1/SERPINF2/TLN1/MYL12A/ADRA2A/VPS45/GNG2	57
BP	GO:0006677	glycosylceramide metabolic process	7/2306	20/18670	0.007804	0.05797	0.0446	B4GALT3/UGCG/NAGA/GLA/UGT8/ALDH5A1/PRKCD	7
BP	GO:0032816	positive regulation of natural killer cell activation	7/2306	20/18670	0.007804	0.05797	0.0446	HLA-E/IL12A/HLA-F/IL15/AXL/GAS6/TICAM1	7
BP	GO:0097709	connective tissue replacement	7/2306	20/18670	0.007804	0.05797	0.0446	IL1A/ROCK1/F2R/PPP3CA/ROCK2/MIR214/MIR199A2	7
BP	GO:0034637	cellular carbohydrate biosynthetic process	19/2306	86/18670	0.007885	0.05843	0.04495	AKR1B1/SLC2A1/PPP1R3F/UGP2/IRS1/PGM2L1/DYRK2/ENPP1/IMPA2/CSGALNACT1/HAS2/CSGALNACT2/HAS1/GYG1/HAS3/GYS2/EXT1/HS2ST1/IGF1	19
BP	GO:0042446	hormone biosynthetic process	19/2306	86/18670	0.007885	0.05843	0.04495	BMP2/AKR1B1/IL1B/NFKB1/DIO2/PPARGC1A/HSD11B1/RDH8/DHRS11/SRD5A1/CYP27B1/VDR/HSD17B12/TNF/HSD17B7/CHST8/HSD17B6/STARD3NL/CYP19A1	19
BP	GO:0006066	alcohol metabolic process	61/2306	364/18670	0.00792	0.05862	0.0451	BMP2/AKR1B1/CH25H/GK/IL1B/NFKB1/PLCD3/ABCA1/FGF2/PLCE1/PLCD1/INSIG2/OSBPL1A/ALDH1A3/MYOF/ACACB/LIMA1/CYP27C1/RDH10/CALM1/RXRA/RDH8/NFE2L1/SCD/GCH1/DHRS3/CYP27B1/TM7SF2/ACAT2/NUDT11/ADH5/ACACA/IMPA2/MOXD1/CYP1A2/NPC1L1/CBR4/SOAT1/PLCB4/SULT1C4/ITPKA/VDR/COQ3/ACAA2/OSBPL5/HSD3B7/TNF/CLN8/HSD17B7/CEBPA/GPAM/INPP5B/PECR/RDH13/ADH1C/IDI1/IP6K3/INPP1/IGF1/PTS/SULT2B1	61
BP	GO:0048511	rhythmic process	51/2306	295/18670	0.007946	0.05874	0.04519	NAMPT/CSF2/RELB/ID2/NFKB2/ADORA2A/PPARGC1A/AHR/EREG/AFP/DBP/NPAS2/SLIT2/ETS1/OXTR/TEF/ADA/SRD5A1/ARNTL/CPT1A/TGFB2/KAT2B/CSNK1E/HAS2/ZFHX3/AXL/IMPDH2/CDK5/SIRT1/ADORA1/ATG7/TIMP4/DDX5/ASS1/HAS1/FZD4/PTX3/ZNF830/LGR4/SERPINE1/NCOR2/ROCK2/PER1/PPARG/ID3/SIK1/MYCBP2/USP9X/MYBBP1A/ARNTL2/MAGEL2	51
BP	GO:0009108	coenzyme biosynthetic process	46/2306	261/18670	0.007981	0.05893	0.04534	NAMPT/PTGS2/PPARGC1A/SLC2A6/KYNU/IDO1/MAT2A/HK2/ACACB/ELOVL5/ENO2/ADPGK/COQ10B/NUP133/SCD/ELOVL7/PGM2L1/GCH1/ACAT1/NNMT/PPT1/PNPO/ACACA/ACSL5/CBR4/PDSS2/ELOVL2/UBIAD1/PARP9/COQ3/PPCS/RGN/HSD17B12/PDHB/PGAM4/PDK3/NUP35/MMADHC/IGF1/STAT3/ALDOC/PTS/P2RX7/SIRT6/SLC25A16/ELOVL3	46
BP	GO:0071706	tumor necrosis factor superfamily cytokine production	32/2306	168/18670	0.008075	0.05955	0.04582	ZC3H12A/TNFAIP3/RIPK2/HSPB1/IFIH1/IFNGR1/HLA-E/IRAK3/DDX58/CCL3/FADD/CYBA/THBS1/ZFP36/AKAP12/SIRPA/MC1R/ERRFI1/BCL3/AXL/WNT5A/AKAP8/HAVCR2/MIR125B1/TLR3/BCL10/GAS6/PTPN11/TICAM1/IGF1/SASH3/ADAM8	32
BP	GO:0048103	somatic stem cell division	8/2306	25/18670	0.008303	0.06073	0.04672	KIT/LBH/ZFP36L2/SOX5/TGFB2/NUMBL/FZD7/AKNA	8
BP	GO:0060330	regulation of response to interferon-gamma	8/2306	25/18670	0.008303	0.06073	0.04672	PARP14/IFNGR1/IFNGR2/STAT1/SOCS1/SOCS3/PARP9/PPARG	8
BP	GO:0060334	regulation of interferon-gamma-mediated signaling pathway	8/2306	25/18670	0.008303	0.06073	0.04672	PARP14/IFNGR1/IFNGR2/STAT1/SOCS1/SOCS3/PARP9/PPARG	8
BP	GO:0032743	positive regulation of interleukin-2 production	9/2306	30/18670	0.008313	0.06073	0.04672	IL1B/CD83/RIPK2/IL1A/PDE4D/TRAF2/ABL1/PDE4B/SASH3	9
BP	GO:0045948	positive regulation of translational initiation	9/2306	30/18670	0.008313	0.06073	0.04672	CCL5/PPP1R15A/RXRA/EIF2AK4/DNAJC3/DHX29/TNF/EIF2B5/YTHDF1	9
BP	GO:0046320	regulation of fatty acid oxidation	9/2306	30/18670	0.008313	0.06073	0.04672	PPARGC1A/ACACB/FABP3/IRS1/CPT1A/ABCD1/APPL2/LONP2/PPARG	9
BP	GO:0071549	cellular response to dexamethasone stimulus	9/2306	30/18670	0.008313	0.06073	0.04672	ICAM1/FOXO1/CFLAR/SRD5A1/SMYD3/ERRFI1/GJB2/ABCC2/ASS1	9
BP	GO:1905476	negative regulation of protein localization to membrane	9/2306	30/18670	0.008313	0.06073	0.04672	PID1/DAB2/PPFIA1/GBP1/CLTC/BCL2L1/MRAP2/GDI1/PICALM	9
BP	GO:0048568	embryonic organ development	70/2306	428/18670	0.008349	0.06091	0.04687	LRIG1/CSF2/LIF/ID2/PLCD3/AHI1/CITED2/KIT/NTN1/CEBPB/MAFB/PLCD1/SIX1/EPAS1/INSIG2/ALDH1A3/VEGFA/BMP4/RAD23B/IRX5/SOCS3/RDH10/NR2F2/PKD2/HOXA11/TTC39C/ADA/STK4/EDN1/PHLDA2/COL5A2/FZD2/HIPK2/ERCC2/TGFB2/YAP1/HOXD9/SETDB2/CEP290/ASCL2/SIX4/MEF2C/JUNB/WNT5A/CDKN1C/PRKRA/FBN1/PTK7/TNF/HOXD3/OSR2/ATP8A2/BIRC6/PDGFC/CEBPA/KRT19/GATA3/HOXB7/ARID1A/PRDM1/EN2/ENG/ID3/FGF10/MIB1/DVL1/OSR1/DVL2/BPTF/TBX3	70
BP	GO:0072676	lymphocyte migration	23/2306	111/18670	0.008379	0.061	0.04693	CCL20/ICAM1/CCL5/CH25H/CXCL10/CCL2/CCL8/CCL7/PIK3CD/TNFRSF14/CCL3L3/CXCL11/CCL3/FADD/ITGA4/SLC12A2/CCL1/WNT5A/HSD3B7/GATA3/GAS6/ADAM8/CRKL	23
BP	GO:0014074	response to purine-containing compound	29/2306	149/18670	0.00838	0.061	0.04693	PTGS2/IL1B/ADORA2A/PPARGC1A/BIRC2/AHR/STAT1/AQP9/PANX1/EEF2K/COL1A1/P2RY11/PKD2/SSH1/SRD5A1/NDUFS4/CARM1/HCN4/ITPR2/JUNB/P2RX3/ASS1/SPARC/CPS1/PDXP/PER1/SLC26A3/PPARG/P2RX7	29
BP	GO:0033628	regulation of cell adhesion mediated by integrin	12/2306	46/18670	0.008468	0.0615	0.04731	CCL5/LPXN/PLAU/ADA/PODXL/TGFB2/SNAI2/SERPINE1/PDE3B/PTPN11/FERMT1/CRKL	12
BP	GO:0071675	regulation of mononuclear cell migration	12/2306	46/18670	0.008468	0.0615	0.04731	CCL5/CXCL10/CSF1/CMKLR1/SLIT2/THBS1/PDGFD/CCL1/AKIRIN1/TNF/SLAMF8/SERPINE1	12
BP	GO:0019935	cyclic-nucleotide-mediated signaling	39/2306	215/18670	0.008646	0.06271	0.04825	CXCL10/ADORA2A/ABCA1/PRKCA/AHR/GIP/PTGFR/CALM1/PDE4D/CXCL11/THBS1/PTGER2/PTHLH/CXCL9/ADM2/MC1R/ADCY7/RGS2/LPAR1/GNA13/NDUFS4/ADCY9/ADCY3/ARRDC3/RAMP1/MRAP2/GPR161/CALM2/MIR1-2/IAPP/ADRB3/LGR4/NPR2/PDE3B/KSR1/NPPA/ADRA2A/CRTC3/GNG2	39
BP	GO:0048813	dendrite morphogenesis	28/2306	143/18670	0.008721	0.06308	0.04853	SLC11A2/SIPA1L1/DBN1/CAPRIN1/EEF2K/FYN/NEUROG3/KIDINS220/SEMA4D/SDC2/HECW2/ITPKA/CDK5/BHLHB9/PDLIM5/YWHAH/DLG4/TMEM106B/PPP3CA/VAMP7/ACTR2/FARP1/CDC42/DVL1/NEDD4/NGEF/ANKRD27/PICALM	28
BP	GO:1903829	positive regulation of cellular protein localization	55/2306	324/18670	0.008725	0.06308	0.04853	ZC3H12A/BID/PTGS2/IL1B/LIF/PPP3CC/SQSTM1/GPD1L/PDCD5/PAK1/NKD2/FYN/STX3/ANK3/SSH1/RUFY3/CCDC88A/PIK3R2/CYLD/UBR5/TCF7L2/RDX/CARD10/PMAIP1/GPSM2/ARIH2/RAB11FIP2/MAP1A/RHOU/CEP290/PARP9/CLIP3/CEP250/GNL3/CDK5/STAC/KCNB1/ARF6/TP63/SESN2/TNF/YWHAH/BAP1/PRKCD/RTN4/NPTN/CTDSPL2/ROCK2/MARK4/GAS6/TFDP1/TMEM30B/RER1/CHP2/EPB41L2	55
BP	GO:0070301	cellular response to hydrogen peroxide	21/2306	99/18670	0.008737	0.06308	0.04853	TNFAIP3/IL6/GPR37L1/FOXO1/KLF2/MYB/PPIF/ETS1/KLF4/NET1/MAPK13/PDGFD/SIRPA/RHOB/STAT6/AXL/SIRT1/TXN/PRKCD/ABL1/SIGMAR1	21
BP	GO:0010821	regulation of mitochondrion organization	34/2306	182/18670	0.008737	0.06308	0.04853	BID/PID1/PPP3CC/PPARGC1A/SQSTM1/PDCD5/HK2/PPIF/LMNA/FNIP2/FNIP1/PMAIP1/ARIH2/STAT2/MMP9/RHOU/TMEM135/OPTN/ATG7/VPS35/BCL2L1/CAMKK2/TP63/ACAA2/PARL/YWHAH/BAP1/IAPP/TMEM14A/VDAC1/TFDP1/FAM162A/ATP13A2/IGF1	34
BP	GO:0050804	modulation of chemical synaptic transmission	71/2306	436/18670	0.008775	0.06328	0.04868	PTGS2/IL1B/CCL2/ADORA2A/KIT/SQSTM1/SIPA1L1/DBN1/SLC7A11/GIP/PLK2/FYN/PNKD/STX3/BACE1/SSH1/OXTR/EDN1/EIF2AK4/AKAP12/RAB3GAP1/F2R/PPP1R9B/NISCH/MAP1A/RPL22/FLOT1/PLCB4/MEF2C/ITPKA/CDK5/RGS4/ADORA1/KCNB1/SNAP47/RAB3A/SYT4/ARF1/PREPL/PFN2/SLC30A1/ABAT/DGKI/P2RX3/TNF/CACNA1B/YWHAH/PXK/ATP2A2/STAU1/DLG4/CNR2/STXBP1/TSHZ3/GRM2/SYT1/GRIK4/PPP3CA/NPTN/GRIN3A/ABL1/TOR1A/YTHDF1/RIN1/NAPB/CNIH2/STAT3/DVL1/PCDH17/TMEM108/PPFIA3	71
BP	GO:0015909	long-chain fatty acid transport	16/2306	69/18670	0.008803	0.06341	0.04878	BDKRB2/SLC27A3/PLA2G4A/PLIN2/ACACB/FABP3/THBS1/CPT1A/ACACA/ABCD1/PLA2G12A/SLC25A20/PRKAB2/PPARG/NMUR2/MID1IP1	16
BP	GO:0033273	response to vitamin	20/2306	93/18670	0.008866	0.06378	0.04907	PTGS2/CXCL10/KYNU/COL1A1/TRIM25/CCND1/IL15/PIM1/ADA/CYP27B1/ITGA2/SNAI2/VDR/TNC/GSN/BGLAP/SPARC/MIR125B1/GAS6/PPARG	20
BP	GO:0006520	cellular amino acid metabolic process	61/2306	366/18670	0.008891	0.06389	0.04915	GFPT2/PSME2/SLC7A2/PSMA6/PSMB10/DDAH1/PSMB8/KYNU/GLS/PSMB7/PSME1/MTHFD2L/IDO1/SLC7A11/PSPH/PSMB9/HIBCH/BCKDHB/PSMA3/IL4I1/NARS2/FAH/P4HA2/ACAT1/GLUD1/BPHL/EGLN1/PCYOX1/HNMT/SEPHS1/PSAT1/AADAT/PLOD2/PSMA1/GAMT/PSMB2/HIBADH/AMT/ALDH7A1/PSMB3/MTR/ABAT/ASS1/BHMT2/ADO/ASNS/DDAH2/ALDH5A1/PHGDH/MTAP/PSMA8/CPS1/FARSB/ENOSF1/PSME4/PSMB5/GNMT/PTS/BCAT2/MARS2/PSMF1	61
BP	GO:1902117	positive regulation of organelle assembly	17/2306	75/18670	0.008932	0.06411	0.04933	CSF2/FSCN1/CCDC88A/EDN1/RAB3GAP1/GPSM2/SDCBP/ARHGEF5/TNF/DYNLL1/MIR1-2/ASAP1/SDC4/MARK4/PIP4K2A/MNS1/PDCD6IP	17
BP	GO:0001892	embryonic placenta development	19/2306	87/18670	0.008949	0.06416	0.04936	CSF2/LIF/PLCD3/CEBPB/PLCD1/EPAS1/SOCS3/NR2F2/PKD2/STK4/PHLDA2/ASCL2/JUNB/CDKN1C/BIRC6/CEBPA/KRT19/PRDM1/BPTF	19
BP	GO:0007031	peroxisome organization	18/2306	81/18670	0.008976	0.06427	0.04945	ACOX2/IDH1/NUDT7/CROT/AMACR/ABCD1/TMEM135/DECR2/PEX11G/LONP2/PEX1/PEX11B/ACOT8/PECR/UBB/SCP2/PEX26/USP9X	18
BP	GO:1903522	regulation of blood circulation	51/2306	297/18670	0.009041	0.06467	0.04975	ZC3H12A/ICAM1/PTGS2/BDKRB2/GPD1L/EPAS1/GJD3/POPDC2/GSTO1/IRX5/CALM1/PDE4D/CAMK2D/BMPR2/HSPB7/GCH1/OXTR/ADA/EDN1/PTGER2/DMPK/HBEGF/TRPC1/F2R/TGFB2/RGS2/THRA/HCN4/ITPR2/RGS4/ADORA1/KCND1/CACNA1F/CACNA1B/CALM2/ATP2A2/MIR1-2/STIM1/DOCK4/SNTA1/NPR2/PDE4B/KCND3/ATP1A4/MYH6/NPPA/PDE5A/SRI/CASQ1/ADORA3/ADRA2A	51
BP	GO:1900024	regulation of substrate adhesion-dependent cell spreading	13/2306	52/18670	0.009142	0.06532	0.05025	PDPN/CORO1C/NEDD9/MYADM/LIMS2/GBP1/HAS2/ARPC2/TACSTD2/ACTN4/ABL1/CDC42/CRKL	13
BP	GO:1901990	regulation of mitotic cell cycle phase transition	72/2306	444/18670	0.009208	0.06553	0.05042	BID/PSME2/CCL2/ID2/PSMA6/CDK6/PSMB10/FHL1/PSMB8/PSMB7/PSME1/PLK2/PSMB9/RPA2/PKD2/CCND1/KLF4/CDC16/PSMA3/CDC25A/SMARCD3/PRMT1/RDX/ZFP36L2/MAD1L1/CDC14B/GJC2/ERCC2/PPP1R9B/DCTN1/HECW2/CSNK1E/CARM1/PSMA1/CEP290/CEP250/PSMB2/CDKN2C/OFD1/NSMCE2/MIR19B2/UBE2E1/BTG2/PSMB3/CDKN1C/MIR137/ARID3A/CEP78/DYNLL1/CNOT8/UBD/NEK6/PSMA8/ZNF830/CDK2AP2/MIR214/CTDSP2/ZFYVE19/CDKN1A/FGF10/PSME4/TFDP1/PSMB5/DCTN3/CDC23/CEP63/MEPCE/PSMG2/TAOK1/FOXO4/PSMF1/NPM2	72
BP	GO:0007520	myoblast fusion	11/2306	41/18670	0.00922	0.06553	0.05042	CXCL10/MYOF/CFLAR/IL4R/CXCL9/FLOT1/EHD1/PLEKHO1/GDF15/MYH9/CAPN2	11
BP	GO:0031214	biomineral tissue development	31/2306	163/18670	0.009221	0.06553	0.05042	BMP2/PTGS2/CEBPB/ISG15/FOXO1/ROCK1/BMP4/COL1A1/BMPR2/CCL3/MSX2/CYP27B1/PTHLH/ENPP1/ERCC2/MEF2C/SRGN/BGLAP/BMP2K/OSR2/RSPO2/STIM1/LGR4/COL1A2/ROCK2/GAS6/IGF1/OSR1/P2RX7/CEMP1/SNX10	31
BP	GO:1903555	regulation of tumor necrosis factor superfamily cytokine production	31/2306	163/18670	0.009221	0.06553	0.05042	ZC3H12A/TNFAIP3/RIPK2/HSPB1/IFIH1/IFNGR1/HLA-E/IRAK3/DDX58/CCL3/FADD/CYBA/THBS1/ZFP36/AKAP12/SIRPA/MC1R/ERRFI1/BCL3/AXL/WNT5A/AKAP8/HAVCR2/MIR125B1/TLR3/GAS6/PTPN11/TICAM1/IGF1/SASH3/ADAM8	31
BP	GO:0099177	regulation of trans-synaptic signaling	71/2306	437/18670	0.009245	0.06553	0.05042	PTGS2/IL1B/CCL2/ADORA2A/KIT/SQSTM1/SIPA1L1/DBN1/SLC7A11/GIP/PLK2/FYN/PNKD/STX3/BACE1/SSH1/OXTR/EDN1/EIF2AK4/AKAP12/RAB3GAP1/F2R/PPP1R9B/NISCH/MAP1A/RPL22/FLOT1/PLCB4/MEF2C/ITPKA/CDK5/RGS4/ADORA1/KCNB1/SNAP47/RAB3A/SYT4/ARF1/PREPL/PFN2/SLC30A1/ABAT/DGKI/P2RX3/TNF/CACNA1B/YWHAH/PXK/ATP2A2/STAU1/DLG4/CNR2/STXBP1/TSHZ3/GRM2/SYT1/GRIK4/PPP3CA/NPTN/GRIN3A/ABL1/TOR1A/YTHDF1/RIN1/NAPB/CNIH2/STAT3/DVL1/PCDH17/TMEM108/PPFIA3	71
BP	GO:0032386	regulation of intracellular transport	69/2306	423/18670	0.009309	0.06553	0.05042	ZC3H12A/PTGS2/IL1B/RAB23/ADORA2A/DAB2/MX2/PDCD5/BMP4/PAK1/REEP6/IL4R/WWC1/FYN/PPP1R12A/BACE1/SNX4/ANK3/RUFY3/PIK3R2/UBR5/CRYAB/TCF7L2/RDX/RAB3GAP1/GCC2/ARIH2/EHD1/RHOU/CEP290/CPSF6/CDK5/KCNB1/ARHGAP1/RAB3A/SYT4/ARF1/PREPL/PFN2/TXN/DGKI/PARL/BRSK2/ATP2A2/BAP1/SP100/STXBP1/GDI1/PRKCD/IWS1/SYT1/GRIN3A/CTDSPL2/GAS6/PKIG/SCP2/VAMP7/PTPN11/NPPA/NAPB/FERMT1/CNIH2/ATP13A2/DVL1/GRIPAP1/NEDD4/TMEM30B/CHP2/SNX3	69
BP	GO:0000041	transition metal ion transport	23/2306	112/18670	0.009344	0.06553	0.05042	SLC39A14/SLC11A2/SLC25A28/ATP6V1E2/ATP6V0B/FTH1/SLC25A37/ATP6V0E2/SLC39A10/SLC39A8/COX17/SLC30A9/CLTC/TRPC1/SLC30A7/ABCC2/ARHGAP1/SLC30A1/CUTC/FTHL17/MCOLN1/STEAP2/ATP6V1E1	23
BP	GO:0014902	myotube differentiation	23/2306	112/18670	0.009344	0.06553	0.05042	CXCL10/SIX1/MYOF/CFLAR/IL4R/SORT1/CXCL9/DMPK/SMYD3/FLOT1/EHD1/PLEKHO1/SIX4/MEF2C/GDF15/BIN3/MIR1-2/PPP3CA/SIK1/MYH9/IGF1/DNER/CAPN2	23
BP	GO:0098693	regulation of synaptic vesicle cycle	23/2306	112/18670	0.009344	0.06553	0.05042	PPP3CC/PLD1/ADORA2A/ROCK1/VAMP4/BACE1/RAB3GAP1/CDK5/RAB3A/SYT4/PREPL/PFN2/DGKI/BRSK2/ATP2A2/STXBP1/SYT1/GRIN3A/TOR1A/NAPB/DVL1/PCDH17/GRIPAP1	23
BP	GO:0001780	neutrophil homeostasis	6/2306	16/18670	0.009385	0.06553	0.05042	IL6/PIK3CD/SLC7A11/JAM3/AXL/PDE4B	6
BP	GO:0002830	positive regulation of type 2 immune response	6/2306	16/18670	0.009385	0.06553	0.05042	IL6/IL33/RSAD2/IDO1/IL4R/GATA3	6
BP	GO:0010934	macrophage cytokine production	6/2306	16/18670	0.009385	0.06553	0.05042	IRAK3/TGFB2/SIRT1/WNT5A/HLA-G/GAS6	6
BP	GO:0014048	regulation of glutamate secretion	6/2306	16/18670	0.009385	0.06553	0.05042	ADORA2A/RAB3GAP1/ADORA1/SYT4/STXBP1/P2RX7	6
BP	GO:0031958	corticosteroid receptor signaling pathway	6/2306	16/18670	0.009385	0.06553	0.05042	ARNTL/YWHAH/ARID1A/PER1/NEDD4/NCOA6	6
BP	GO:0042033	chemokine biosynthetic process	6/2306	16/18670	0.009385	0.06553	0.05042	IL6/IL1B/WNT5A/TNF/TLR3/TICAM1	6
BP	GO:0050755	chemokine metabolic process	6/2306	16/18670	0.009385	0.06553	0.05042	IL6/IL1B/WNT5A/TNF/TLR3/TICAM1	6
BP	GO:0055119	relaxation of cardiac muscle	6/2306	16/18670	0.009385	0.06553	0.05042	PDE4D/CAMK2D/RGS2/ATP2A2/PDE4B/PDE5A	6
BP	GO:0060572	morphogenesis of an epithelial bud	6/2306	16/18670	0.009385	0.06553	0.05042	BMP4/RDH10/WNT5A/SULF1/TP63/FGF10	6
BP	GO:0071786	endoplasmic reticulum tubular network organization	6/2306	16/18670	0.009385	0.06553	0.05042	ZFYVE27/RAB3GAP1/RAB18/ATL1/RTN4/TMEM33	6
BP	GO:0072189	ureter development	6/2306	16/18670	0.009385	0.06553	0.05042	NFIA/SIX1/LZTS2/BMP4/GATA3/OSR1	6
BP	GO:0007266	Rho protein signal transduction	37/2306	203/18670	0.009582	0.06673	0.05134	ABCA1/NTN1/PDPN/ROCK1/ARHGEF10/PDGFRB/CDC42EP1/CDC42EP3/RHOJ/NET1/F2R/RHOB/FGD4/LPAR1/GNA13/RHOBTB3/FGD1/GNA12/FLOT1/RHOU/ROBO1/ARHGAP1/ARHGEF5/EPS8/TIAM2/ARHGEF17/ARHGEF12/PLEKHG4/ABL1/COL1A2/ROCK2/ARHGDIB/FARP1/CDC42/NGEF/PLEKHG2/ADRA2A	37
BP	GO:0002456	T cell mediated immunity	22/2306	106/18670	0.009588	0.06673	0.05134	ICAM1/IL6/CD70/IL1B/IL7R/RSAD2/TNFRSF1B/HLA-E/IL12A/IL18R1/HLA-F/FADD/HLA-A/BTN3A3/TRAF2/MICB/GATA3/HLA-G/P2RX7/HLA-B/SASH3/HLA-H	22
BP	GO:1904029	regulation of cyclin-dependent protein kinase activity	22/2306	106/18670	0.009588	0.06673	0.05134	TNFAIP3/NR2F2/LATS2/PKD2/CCND1/CDC25A/CCNO/SERTAD1/KAT2B/HEXIM2/CCNG2/CDKN2C/CDKN1C/CCNYL1/ACTB/CCNG1/HERC5/CEBPA/CCNJL/CDKN1A/MNAT1/CDK7	22
BP	GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors	14/2306	58/18670	0.009625	0.06691	0.05148	ICAM1/TNFAIP3/CFLAR/FAS/FADD/THBS1/STK4/PMAIP1/TRAF2/BCL2L1/TNFRSF10B/SP100/ITPRIP/SERPINE1	14
BP	GO:0061640	cytoskeleton-dependent cytokinesis	21/2306	100/18670	0.009806	0.06801	0.05233	CHMP1B/ROCK1/LZTS2/ACTR3/CHMP4B/ANK3/FMN2/SON/RHOB/KLHDC8B/NOX5/KIF4B/ARF1/BIN3/CHMP5/ROCK2/MITD1/ACTR2/DCTN3/MYH10/PDCD6IP	21
BP	GO:0090174	organelle membrane fusion	21/2306	100/18670	0.009806	0.06801	0.05233	TAP1/TAP2/SAMD9L/NKD2/BET1/VAMP4/STX3/STX6/TBC1D4/SNAP47/RAB3A/SYT4/TMEM175/SAMD9/STXBP1/SYT1/STX16/VAMP7/TAPBP/TSNARE1/ANKRD27	21
BP	GO:0006699	bile acid biosynthetic process	10/2306	36/18670	0.009911	0.06838	0.05261	CH25H/ACOX2/OSBPL1A/AMACR/SIRT1/OSBPL3/HSD3B7/ACOT8/SCP2/OSBPL7	10
BP	GO:0035137	hindlimb morphogenesis	10/2306	36/18670	0.009911	0.06838	0.05261	PITX1/BMP4/MSX2/HOXD9/GDF5/TP63/OSR2/RSPO2/OSR1/TBX3	10
BP	GO:1901099	negative regulation of signal transduction in absence of ligand	10/2306	36/18670	0.009911	0.06838	0.05261	CSF2/IL1B/IL1A/FYN/SNAI2/BCL2L1/TNF/FGF10/EYA2/SGK3	10
BP	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	10/2306	36/18670	0.009911	0.06838	0.05261	CSF2/IL1B/IL1A/FYN/SNAI2/BCL2L1/TNF/FGF10/EYA2/SGK3	10
BP	GO:0048638	regulation of developmental growth	58/2306	347/18670	0.009934	0.06838	0.05261	CSF1/NTN1/BASP1/FGF2/MEIS1/JARID2/ZFYVE27/SIX1/DBN1/DUSP6/VEGFA/BMP4/PAK1/ACACB/WWC1/FTO/BMPR2/LATS2/RUFY3/PIM1/STK4/EDN1/PHLDA2/GHR/SEMA4D/RGS2/GATA6/BBS2/YAP1/GDF5/CARM1/IFRD1/SIX4/GAMT/MEF2C/CDK5/MIR19B2/WNT5A/RGS4/SYT4/GDF15/SH3PXD2B/MIR1-2/ATP8A2/SOCS2/GDI1/SYT1/RTN4/ABL1/DUSP10/CDKN1A/MYH6/SEMA4F/MIR199A2/IGF1/CDH4/STAT3/SASH3	58
BP	GO:0036498	IRE1-mediated unfolded protein response	15/2306	64/18670	0.009947	0.06838	0.05261	ERN1/FICD/DNAJB9/LMNA/HDGF/WIPI1/DCTN1/DNAJC3/HYOU1/SSR1/CTDSP2/TSPYL2/TLN1/TMEM33/BFAR	15
BP	GO:0045669	positive regulation of osteoblast differentiation	15/2306	64/18670	0.009947	0.06838	0.05261	BMP2/IL6/CEBPD/CEBPB/IFITM1/IL6ST/BMP4/BMPR2/MSX2/LRP5/MEF2C/TP63/CEBPA/IGF1/ZHX3	15
BP	GO:0060135	maternal process involved in female pregnancy	15/2306	64/18670	0.009947	0.06838	0.05261	AKR1B1/PTGS2/LIF/RXRA/NR2F2/BMPR2/CYP27B1/ADCY7/RGS2/LDOC1/GJB2/VDR/JUNB/HAVCR2/PRDM1	15
BP	GO:0007416	synapse assembly	33/2306	177/18670	0.009963	0.06841	0.05264	THBS2/NTN1/SIX1/EEF2K/FZD1/GPC4/OXTR/SEMA4D/TPBG/FLRT2/SIX4/MEF2C/CDK5/WNT5A/VPS35/ARF6/BHLHB9/LHFPL4/FLRT3/PDLIM5/LRRN1/SLITRK4/PLXND1/LRFN4/AMIGO3/NPTN/FARP1/PCDHB13/DVL1/PCDH17/CRKL/DNER/LRRN3	33
BP	GO:0008584	male gonad development	27/2306	138/18670	0.009978	0.06843	0.05265	ICAM1/CITED2/KIT/ARID5B/RAB13/PDGFRB/BCL2L2/CCND1/HOXA11/HOXA10/SRD5A1/TGFB2/GATA6/NUDT1/RHOBTB3/SIX4/WNT5A/NKX3-1/BCL2L1/MAMLD1/HOXA9/TLR3/GATA3/EIF2S2/UBB/CRKL/ARID4A	27
BP	GO:0045621	positive regulation of lymphocyte differentiation	20/2306	94/18670	0.009988	0.06843	0.05265	NFKBIZ/CD83/RIPK2/TNFSF9/IL7R/IL12A/MYB/IL4R/SOCS1/IL15/CYLD/ADA/AXL/GATA3/HLA-G/DUSP10/GAS6/SASH3/ADAM8/CBFB	20
BP	GO:0044242	cellular lipid catabolic process	39/2306	217/18670	0.01005	0.06872	0.05287	LPIN1/ACOX2/PLA2G4A/ACACB/AIG1/FABP3/HIBCH/PLA2G4C/IRS1/IDH1/NUDT7/CROT/NAGA/GLA/ACAT1/HADH/PPT1/ACAT2/LIPG/CPT1A/AMACR/ABCD1/DAGLA/SESN2/ACAA2/DECR2/DAGLB/ABHD5/ABHD3/PRKCD/LONP2/CPS1/BDH2/ACOT8/PECR/SCP2/MGST2/ACOXL/ACADM	39
BP	GO:0050920	regulation of chemotaxis	39/2306	217/18670	0.01005	0.06872	0.05287	CCL5/IL6/CXCL10/CCL2/HSPB1/ZSWIM4/CSF1/CCL7/FGF2/VEGFA/JAM3/PDGFRB/IL12A/CMKLR1/SLIT2/BMPR2/STX3/CCL3/THBS1/EDN1/SEMA4D/PDGFD/CCL1/ITGA2/LPAR1/DUSP3/ROBO1/AKIRIN1/WNT5A/PGF/SLAMF8/USP14/SERPINE1/GAS6/YTHDF1/FGF10/SEMA4F/MYCBP2/CYP19A1	39
BP	GO:0006953	acute-phase response	12/2306	47/18670	0.01012	0.06899	0.05308	PTGS2/IL6/IL1B/IL1A/CEBPB/PLSCR1/TNF/ASS1/SERPINA3/STAT3/SERPINA1/SERPINF2	12
BP	GO:0008206	bile acid metabolic process	12/2306	47/18670	0.01012	0.06899	0.05308	CH25H/KIT/ATP8B1/ACOX2/OSBPL1A/AMACR/SIRT1/OSBPL3/HSD3B7/ACOT8/SCP2/OSBPL7	12
BP	GO:0106027	neuron projection organization	19/2306	88/18670	0.01013	0.06899	0.05308	SIPA1L1/DBN1/CAPRIN1/EEF2K/FYN/DCTN1/MAP1A/ABCD1/ITPKA/CDK5/VPS35/BHLHB9/ARF1/PDLIM5/DLG4/ACTR2/CDC42/DVL1/NGEF	19
BP	GO:0034121	regulation of toll-like receptor signaling pathway	16/2306	70/18670	0.01014	0.06899	0.05308	BIRC3/TNFAIP3/IRF1/BIRC2/RSAD2/IRF7/IRAK3/CYBA/FLOT1/WDFY1/APPL2/TLR3/RTN4/LGR4/PJA2/TICAM1	16
BP	GO:0045766	positive regulation of angiogenesis	37/2306	204/18670	0.01035	0.06993	0.05381	ZC3H12A/PTGS2/IL1B/HSPB1/IL1A/FGF2/DDAH1/PRKCA/C3/VEGFA/HK2/PLK2/CD40/RHOJ/ETS1/KLF4/THBS1/BMPER/ADM2/HIPK2/RHOB/ITGB8/GATA6/SIRT1/WNT5A/PGF/MIR1-2/STIM1/TLR3/SERPINE1/ABL1/EPHA1/ENG/MIR199A2/AGGF1/STAT3/SIRT6	37
BP	GO:0045995	regulation of embryonic development	26/2306	132/18670	0.01037	0.06993	0.05381	SIX1/BMP4/FZD1/MYADM/KLF4/STK4/PHLDA2/MBP/COL5A2/FZD2/PHLDB1/SIX4/PHLDB2/WNT5A/SULF1/HES5/PTK7/GPR161/MIR1-2/GATA3/IGF1/DVL1/OSR1/DVL2/COL5A1/FZD7	26
BP	GO:0002223	stimulatory C-type lectin receptor signaling pathway	23/2306	113/18670	0.0104	0.06993	0.05381	PSME2/RELB/NFKB1/PSMA6/PSMB10/PSMB8/PSMB7/PSME1/PAK1/PSMB9/FYN/PSMA3/PSMA1/PSMB2/PSMB3/PRKCD/PSMA8/BCL10/MUC15/MUC17/PSME4/PSMB5/PSMF1	23
BP	GO:0002724	regulation of T cell cytokine production	9/2306	31/18670	0.01046	0.06993	0.05381	IL6/IL1B/RSAD2/TNFRSF1B/IL18R1/HLA-F/TRAF2/GATA3/SASH3	9
BP	GO:0002888	positive regulation of myeloid leukocyte mediated immunity	9/2306	31/18670	0.01046	0.06993	0.05381	C3/HLA-E/IL4R/DDX58/SNX4/STXBP1/VAMP7/NPPA/TICAM1	9
BP	GO:0009954	proximal/distal pattern formation	9/2306	31/18670	0.01046	0.06993	0.05381	IRX3/HOXA11/HOXA10/HOXD9/TP63/HES5/HOXA9/FGF10/OSR1	9
BP	GO:0050849	negative regulation of calcium-mediated signaling	9/2306	31/18670	0.01046	0.06993	0.05381	GSTO1/CALM1/PKD2/FHL2/DYRK2/RCAN1/CALM2/SRI/HOMER2	9
BP	GO:1903393	positive regulation of adherens junction organization	9/2306	31/18670	0.01046	0.06993	0.05381	VEGFA/ROCK1/IQSEC1/DUSP3/ARF6/COL16A1/SDC4/MAPRE2/ABL1	9
BP	GO:0015874	norepinephrine transport	7/2306	21/18670	0.01048	0.06993	0.05381	ADORA2A/SLC22A1/OXTR/NISCH/KCNB1/ACTB/ADRA2A	7
BP	GO:0032516	positive regulation of phosphoprotein phosphatase activity	7/2306	21/18670	0.01048	0.06993	0.05381	ITGA1/PPP1R15A/PDGFRB/CALM1/PPP1R12A/SLC39A10/CALM2	7
BP	GO:0032891	negative regulation of organic acid transport	7/2306	21/18670	0.01048	0.06993	0.05381	ARL6IP5/THBS1/RGS2/RGS4/ADORA1/ABAT/OSR1	7
BP	GO:0035357	peroxisome proliferator activated receptor signaling pathway	7/2306	21/18670	0.01048	0.06993	0.05381	CITED2/RXRA/SIRT1/ACTN4/PDK3/PPARG/FAM120B	7
BP	GO:0036120	cellular response to platelet-derived growth factor stimulus	7/2306	21/18670	0.01048	0.06993	0.05381	PDGFRB/FYN/RDX/PDGFD/ERRFI1/HAS2/HAS1	7
BP	GO:0042402	cellular biogenic amine catabolic process	7/2306	21/18670	0.01048	0.06993	0.05381	KYNU/SAT1/IDO1/SMOX/HNMT/AADAT/ALDH7A1	7
BP	GO:0061213	positive regulation of mesonephros development	7/2306	21/18670	0.01048	0.06993	0.05381	BASP1/SIX1/VEGFA/SIX4/GATA3/HOXB7/LGR4	7
BP	GO:0071498	cellular response to fluid shear stress	7/2306	21/18670	0.01048	0.06993	0.05381	PTGS2/KLF2/PKD2/KLF4/HAS2/MEF2C/ASS1	7
BP	GO:0140058	neuron projection arborization	7/2306	21/18670	0.01048	0.06993	0.05381	ROCK1/MOV10/WNT5A/FZD4/DLG4/DVL1/DVL2	7
BP	GO:2001014	regulation of skeletal muscle cell differentiation	7/2306	21/18670	0.01048	0.06993	0.05381	SIX1/ARNTL/SIX4/MEF2C/AKIRIN1/DDX5/MIR1-2	7
BP	GO:0015697	quaternary ammonium group transport	5/2306	12/18670	0.01071	0.0707	0.0544	SLC22A1/SLC38A2/SLC22A4/SLC25A20/SLC22A3	5
BP	GO:0043476	pigment accumulation	5/2306	12/18670	0.01071	0.0707	0.0544	RAB38/SHROOM3/RAB32/SHROOM2/ANKRD27	5
BP	GO:0043482	cellular pigment accumulation	5/2306	12/18670	0.01071	0.0707	0.0544	RAB38/SHROOM3/RAB32/SHROOM2/ANKRD27	5
BP	GO:0045080	positive regulation of chemokine biosynthetic process	5/2306	12/18670	0.01071	0.0707	0.0544	IL1B/WNT5A/TNF/TLR3/TICAM1	5
BP	GO:0051798	positive regulation of hair follicle development	5/2306	12/18670	0.01071	0.0707	0.0544	MSX2/TGFB2/WNT5A/TNF/FST	5
BP	GO:0090085	regulation of protein deubiquitination	5/2306	12/18670	0.01071	0.0707	0.0544	ZC3H12A/TNIP1/ITCH/TRIM21/UBXN1	5
BP	GO:0010460	positive regulation of heart rate	8/2306	26/18670	0.01072	0.0707	0.0544	PDE4D/GCH1/ADA/EDN1/RGS4/ATP2A2/MIR1-2/NPPA	8
BP	GO:0045992	negative regulation of embryonic development	8/2306	26/18670	0.01072	0.0707	0.0544	BMP4/COL5A2/WNT5A/SULF1/GPR161/GATA3/COL5A1/FZD7	8
BP	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity	8/2306	26/18670	0.01072	0.0707	0.0544	GSTO1/CALM1/PDE4D/CAMK2D/PKD2/CALM2/FKBP1A/SRI	8
BP	GO:0060740	prostate gland epithelium morphogenesis	8/2306	26/18670	0.01072	0.0707	0.0544	BMP4/RXRA/WNT5A/NKX3-1/SULF1/TP63/TNC/FGF10	8
BP	GO:0080111	DNA demethylation	8/2306	26/18670	0.01072	0.0707	0.0544	APOBEC3G/FTO/TET1/APOBEC3H/TET3/GATA3/APOBEC3F/USP9X	8
BP	GO:0046890	regulation of lipid biosynthetic process	36/2306	198/18670	0.0109	0.07182	0.05525	BMP2/PTGS2/IL1B/NFKB1/PPARGC1A/C3/INSIG2/GIP/ACACB/ELOVL5/RDH10/RAB38/FABP3/SCD/DDX20/IDH1/TRIB3/CYP27B1/TM7SF2/ACACA/SNAI2/ADIPOR2/ABCD1/VDR/SIRT1/RGN/TNF/GPAM/PRKAB2/PRKCD/NSMAF/IDI1/SIK1/SAMD8/MID1IP1/CAPN2	36
BP	GO:0002700	regulation of production of molecular mediator of immune response	27/2306	139/18670	0.01097	0.07217	0.05552	IL6/IL1B/IL33/TNFRSF14/RSAD2/TNFRSF1B/HLA-E/IL18R1/IL4R/HLA-F/CD40/IRAK3/DDX58/EXOSC6/TGFB2/CLCF1/STAT6/WNT5A/TRAF2/TNF/TLR3/TRIM6/GATA3/HLA-G/BCL10/TICAM1/SASH3	27
BP	GO:0046545	development of primary female sexual characteristics	21/2306	101/18670	0.01098	0.07217	0.05553	ICAM1/KIT/CEBPB/ARID5B/VEGFA/EREG/AFP/SLIT2/IDH1/LHX8/INHBB/LHFPL2/SIRT1/BCL2L1/FZD4/EIF2B5/EIF2B4/PTX3/ZNF830/UBB/CYP19A1	21
BP	GO:0017145	stem cell division	11/2306	42/18670	0.01113	0.07297	0.05614	KIT/WWTR1/LBH/ZFP36L2/SOX5/TGFB2/GNL3/NUMBL/CDK2AP2/FZD7/AKNA	11
BP	GO:0042149	cellular response to glucose starvation	11/2306	42/18670	0.01113	0.07297	0.05614	ZC3H12A/SESN1/SLC2A1/TBL2/PMAIP1/SESN3/SESN2/ASNS/KPTN/SIK1/MYBBP1A	11
BP	GO:1904062	regulation of cation transmembrane transport	57/2306	342/18670	0.01113	0.07297	0.05614	BDKRB1/CXCL10/CCL2/PPARGC1A/FHL1/CNKSR3/GPD1L/DAPK1/CTSS/GSTO1/RRAD/PPIF/FYN/CALM1/PDE4D/CAMK2D/PKD2/CXCL11/ANK3/CYBA/UBASH3B/CXCL9/COX17/THADA/TRPC1/F2R/GJC2/RGS2/GRIA3/HECW2/MMP9/MEF2C/GEM/NOX5/STAC/RGS4/RGN/ARF1/SLC30A1/YWHAH/CALM2/ACTN4/MIR1-2/DLG4/STIM1/FKBP1A/DIAPH1/SNTA1/ABL1/PDE4B/NPPA/CNIH2/OSR1/SRI/CASQ1/NEDD4/ADRA2A	57
BP	GO:0023061	signal release	74/2306	462/18670	0.01115	0.07297	0.05614	CCL5/IL6/IL1B/LIF/ENSA/ADORA2A/C1QTNF1/PRKCA/SLC22A2/SLC2A1/GIP/PPFIA1/MYB/PNKD/IRS1/STX3/BACE1/SNX4/GLUD1/EDN1/HADH/TCF7L2/RAB3GAP1/PPT1/INHBB/ARNTL/CPT1A/RAB11FIP2/LIN7A/LRP5/ITPR2/MEF2C/CDK5/ADORA1/KCNB1/NKX3-1/SNAP47/VPS35/RAB3A/SYT4/PREPL/PFN2/SLC30A1/ABAT/DGKI/TNF/CACNA1B/CAMK2G/SYTL4/RPH3A/DYNLL1/BRSK2/ATP2A2/FZD4/SNPH/STXBP1/GATA3/SYT1/PPP3CA/GRIN3A/RAB11FIP1/VAMP7/PTPN11/NPPA/NAPB/DVL1/ARL2BP/LIN7C/SRI/P2RX7/PPFIA3/CYP19A1/ADRA2A/TBX3	74
BP	GO:1903708	positive regulation of hemopoiesis	34/2306	185/18670	0.01116	0.07299	0.05616	NFKBIZ/LIF/CD83/RIPK2/ID2/TRIB1/CSF1/TNFSF9/ISG15/IL7R/PRKCA/STAT1/IL12A/MYB/IL4R/SOCS1/ETS1/FADD/IL15/CYLD/ADA/PRMT1/TMEM64/ACIN1/AXL/TNF/GATA3/HLA-G/DUSP10/GAS6/STAT3/SASH3/ADAM8/CBFB	34
BP	GO:0044839	cell cycle G2/M phase transition	46/2306	266/18670	0.01119	0.0731	0.05624	PSME2/ENSA/PSMA6/PSMB10/TPD52L1/FHL1/PSMB8/PSMB7/PSME1/PHLDA1/PSMB9/PPP1R12A/CCND1/PSMA3/CDC25A/SMARCD3/CDC14B/DCTN1/CSNK1E/PSMA1/CEP290/CEP250/PSMB2/OFD1/OPTN/MIR19B2/AKAP8/PSMB3/CEP78/PPM1D/DYNLL1/BRSK2/PSMA8/ZNF830/ZFYVE19/CDKN1A/MNAT1/PSME4/PSMB5/DCTN3/CEP63/TAOK1/CDK7/UIMC1/FOXO4/PSMF1	46
BP	GO:1903076	regulation of protein localization to plasma membrane	20/2306	95/18670	0.01122	0.07323	0.05634	PID1/DAB2/SQSTM1/NKD2/PPFIA1/STX3/GBP1/CLTC/RAB11FIP2/CLIP3/CDK5/STAC/ARF6/BCL2L1/MRAP2/ACTB/TNF/GRIPAP1/RER1/PICALM	20
BP	GO:0032410	negative regulation of transporter activity	19/2306	89/18670	0.01142	0.07439	0.05723	GSTO1/RRAD/PPIF/CALM1/CAMK2D/PKD2/ANK3/NDFIP1/THADA/HECW2/MMP9/GEM/CALM2/MIR1-2/NDFIP2/OSR1/SRI/NEDD4/ADRA2A	19
BP	GO:0097306	cellular response to alcohol	19/2306	89/18670	0.01142	0.07439	0.05723	ABCA1/CCL7/AHR/KLF2/PTGFR/NFE2L1/KLF4/PTGER2/ADCY7/TP53INP1/ACACA/ADCY3/ITPR2/AKAP8/TNC/PPARG/OSBPL7/GNG2/GRAMD1A	19
BP	GO:0048839	inner ear development	35/2306	192/18670	0.01148	0.07452	0.05734	BMP2/LRIG1/CEBPD/AHI1/NTN1/ATP8B1/MAFB/SIX1/INSIG2/ALDH1A3/BMP4/PDGFRB/TTC39C/BMPER/CYTL1/ROR1/FZD2/TGFB2/LIN7A/GJB2/CEP290/SIX4/WNT5A/HES5/PTK7/SPARC/ATP8A2/CEBPA/GATA3/SDC4/PCDH15/PTPN11/FGF10/DVL1/DVL2	35
BP	GO:1901136	carbohydrate derivative catabolic process	35/2306	192/18670	0.01148	0.07452	0.05734	FGF2/GPD1L/TYMP/APOBEC3G/GPC4/CD44/NAGK/PDE4D/VCAN/PDE1A/HSPG2/AMPD3/NUDT18/NUDT7/ADA/NAGA/GLA/ACAT1/NCCRP1/GLB1/APOBEC3H/NUDT11/SDC2/NUDT1/ABCD1/CDADC1/MGAT1/PRKCD/SDC4/FBXO17/APOBEC3F/MBD4/PDE4B/PDE5A/HINT1	35
BP	GO:0006940	regulation of smooth muscle contraction	15/2306	65/18670	0.01149	0.07452	0.05734	PTGS2/KIT/PLCE1/OXTR/ADA/EDN1/F2R/RGS2/ITGA2/ADORA1/ABAT/DOCK4/NMUR2/KCNB2/ADRA2A	15
BP	GO:0072678	T cell migration	15/2306	65/18670	0.01149	0.07452	0.05734	CCL20/ICAM1/CCL5/CXCL10/CCL2/PIK3CD/TNFRSF14/CXCL11/CCL3/FADD/ITGA4/SLC12A2/WNT5A/ADAM8/CRKL	15
BP	GO:0006970	response to osmotic stress	18/2306	83/18670	0.01157	0.07494	0.05765	AKR1B1/PTGS2/RELB/CLDN1/BDKRB2/TSC22D2/SLC2A1/AQP9/PKD2/SLC12A2/MAPK13/HNMT/ITGA2/ERRFI1/LRRC8E/MYLK/TNF/TLR3	18
BP	GO:0033692	cellular polysaccharide biosynthetic process	16/2306	71/18670	0.01162	0.07522	0.05787	PPP1R3F/UGP2/IRS1/PGM2L1/DYRK2/ENPP1/CSGALNACT1/HAS2/CSGALNACT2/HAS1/GYG1/HAS3/GYS2/EXT1/HS2ST1/IGF1	16
BP	GO:0007584	response to nutrient	39/2306	219/18670	0.01164	0.07526	0.0579	PTGS2/VCAM1/IL1B/CXCL10/ENSA/ABCA1/KYNU/STAT1/PANX1/COL1A1/TRIM25/FYN/BCKDHB/P2RY11/CCND1/SSH1/CYBA/IL15/PIM1/ADA/CYP27B1/LIPG/ITGA2/SNAI2/ADIPOR2/VDR/TNC/GSN/P2RX3/BGLAP/ASS1/SPARC/MIR125B1/PDXP/GAS6/DAD1/PPARG/TNFRSF11B/P2RX7	39
BP	GO:0048771	tissue remodeling	33/2306	179/18670	0.01174	0.07572	0.05826	TNFAIP3/IL6/LIF/IL1A/PRKCA/EPAS1/ROCK1/LIPA/BMPR2/IL15/UBASH3B/F2R/MITF/TMEM64/GDF5/LRP5/AXL/MEF2C/VDR/BGLAP/ELF3/IAPP/PPP3CA/LGR4/ROCK2/MIR214/FGF10/TNFRSF11B/MIR199A2/P2RX7/ADAM8/ZNF675/SNX10	33
BP	GO:0018209	peptidyl-serine modification	54/2306	322/18670	0.01174	0.07572	0.05826	PTGS2/IL6/LIF/RIPK2/BDKRB2/ERN1/CNKSR3/PRKCA/GPD1L/VEGFA/ROCK1/PLK2/PAK1/CD44/BCAR3/PDE4D/CAMK2D/LATS2/FNIP2/DYRK2/MKNK2/STK4/MAPK13/STK38L/DMPK/FNIP1/HIPK2/SMYD3/CSNK1G2/RPS6KA4/CSNK1E/CDK5/WNT5A/ARAF/MTCP1/PFN2/TXN/TNF/TLK1/BRSK2/NEK6/TRIM6/PRKCD/PDK3/ROCK2/GALNT4/GAS6/PKN2/CSNK1G3/GALNT1/MAST4/DCLK2/SGK3/MORC3	54
BP	GO:0017038	protein import	36/2306	199/18670	0.01177	0.07584	0.05835	NFKBIA/ZC3H12A/PTGS2/RAB23/PDCD5/BMP4/DNAJC19/NUP133/LMNA/PIK3R2/UBR5/ARNTL/KPNA3/DNAJC15/RPAIN/ARHGEF5/APPL2/GRPEL1/GRPEL2/PRKCD/LONP2/PEX1/PPP3CA/CHCHD4/NXT1/PKIG/CDKN1A/KPNA2/RANBP17/NUP35/PEX26/FERMT1/CBLB/STAT3/CHP2/TIMM17B	36
BP	GO:0043620	regulation of DNA-templated transcription in response to stress	25/2306	127/18670	0.01188	0.07647	0.05884	PSME2/PSMA6/PSMB10/CITED2/CEBPB/PSMB8/PSMB7/PSME1/EPAS1/VEGFA/KLF2/PSMB9/PSMA3/BCLAF1/EGLN1/PSMA1/PSMB2/PSMB3/SESN2/PSMA8/UBB/PSME4/PSMB5/NEDD4/PSMF1	25
BP	GO:1904659	glucose transmembrane transport	22/2306	108/18670	0.01191	0.07661	0.05894	PID1/IL1B/SLC2A6/C3/SLC2A1/HK2/GIP/SORT1/IRS1/TRIB3/EDN1/ENPP1/SLC2A12/ADIPOR2/CLIP3/SESN2/TNF/APPL2/PTPN11/IGF1/SLC2A10/SIRT6	22
BP	GO:0007528	neuromuscular junction development	12/2306	48/18670	0.01202	0.07696	0.05921	SIX1/PDZRN3/ANK3/F2R/DCTN1/SIX4/TNC/COL4A1/DVL1/NEDD4/CRKL/RER1	12
BP	GO:0030865	cortical cytoskeleton organization	12/2306	48/18670	0.01202	0.07696	0.05921	ROCK1/RAB13/EPB41L3/FMNL2/CDK5/ARF6/TNF/EPB41L1/ROCK2/TLN1/PDCD6IP/EPB41L2	12
BP	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	12/2306	48/18670	0.01202	0.07696	0.05921	ITGA1/GPRC5A/EREG/EPS15/TGFA/HBEGF/SPRY1/ERRFI1/DUSP3/CDC42/CBLB/RNF126	12
BP	GO:0045933	positive regulation of muscle contraction	12/2306	48/18670	0.01202	0.07696	0.05921	PTGS2/KIT/GSTO1/OXTR/ADA/EDN1/F2R/RGS2/ITGA2/ABAT/MIR1-2/NPPA	12
BP	GO:0046330	positive regulation of JNK cascade	27/2306	140/18670	0.01203	0.07697	0.05922	IL1B/RIPK2/SH3RF1/ERN1/TPD52L1/DAXX/ANKRD6/PAK1/EDN1/SDCBP/HIPK2/GADD45G/FZD8/WNT5A/TRAF2/ARHGEF5/TNF/MAP3K2/MLKL/FZD4/TLR3/PJA2/SH3RF2/DVL2/SERPINF2/TAOK1/FZD7	27
BP	GO:0045923	positive regulation of fatty acid metabolic process	10/2306	37/18670	0.01211	0.07717	0.05937	PTGS2/IL1B/PPARGC1A/ELOVL5/IRS1/CPT1A/ABCD1/RGN/PPARG/MID1IP1	10
BP	GO:1903427	negative regulation of reactive oxygen species biosynthetic process	10/2306	37/18670	0.01211	0.07717	0.05937	ZC3H12A/CFLAR/FYN/GLA/SIRPA/ABCD1/RGN/ROCK2/MIR199A2/STAT3	10
BP	GO:1905314	semi-lunar valve development	10/2306	37/18670	0.01211	0.07717	0.05937	TNFRSF1B/ROCK1/BMP4/SLIT2/BMPR2/TGFB2/SNAI2/ROBO1/GATA3/ROCK2	10
BP	GO:2000403	positive regulation of lymphocyte migration	10/2306	37/18670	0.01211	0.07717	0.05937	CCL20/CCL5/CXCL10/CCL7/TNFRSF14/CCL3/FADD/ITGA4/WNT5A/ADAM8	10
BP	GO:0043618	regulation of transcription from RNA polymerase II promoter in response to stress	24/2306	121/18670	0.01234	0.07852	0.06041	PSME2/PSMA6/PSMB10/CITED2/CEBPB/PSMB8/PSMB7/PSME1/EPAS1/VEGFA/KLF2/PSMB9/PSMA3/EGLN1/PSMA1/PSMB2/PSMB3/SESN2/PSMA8/UBB/PSME4/PSMB5/NEDD4/PSMF1	24
BP	GO:0000086	G2/M transition of mitotic cell cycle	43/2306	247/18670	0.01237	0.07864	0.0605	PSME2/ENSA/PSMA6/PSMB10/TPD52L1/FHL1/PSMB8/PSMB7/PSME1/PHLDA1/PSMB9/PPP1R12A/CCND1/PSMA3/CDC25A/SMARCD3/DCTN1/CSNK1E/PSMA1/CEP290/CEP250/PSMB2/OFD1/OPTN/MIR19B2/PSMB3/CEP78/PPM1D/DYNLL1/BRSK2/PSMA8/ZNF830/ZFYVE19/CDKN1A/MNAT1/PSME4/PSMB5/DCTN3/CEP63/TAOK1/CDK7/FOXO4/PSMF1	43
BP	GO:0007219	Notch signaling pathway	35/2306	193/18670	0.0124	0.07876	0.0606	NFKBIA/BMP2/S1PR3/CDK6/GDPD5/KIT/STAT1/IL6ST/WWC1/GMDS/BEND6/ITCH/TGFB2/KAT2B/SNAI2/APH1B/ROBO1/PSENEN/ANXA4/TP63/HES5/TIMP4/HOXD3/RBM15/ELF3/PLXND1/PEAR1/CEBPA/KRT19/FGF10/MIB1/STAT3/GALNT11/SLC35C1/DNER	35
BP	GO:0010721	negative regulation of cell development	57/2306	344/18670	0.01248	0.07918	0.06092	IL6/GPR37L1/IL1B/S1PR3/ID2/NTN1/MEIS1/DENND5A/CORO1C/VEGFA/PLK2/PAK1/SLIT2/IRX3/RUFY3/GBP1/EIF2AK4/PTHLH/DPYSL3/DIXDC1/SEMA4D/RGS2/LPAR1/DAAM2/CARM1/ASCL2/IFRD1/CDK5/WNT5A/RGS4/ARF6/SYT4/HES5/MIR137/FBN1/TNF/YWHAH/APPL2/HOOK3/TACSTD2/ACTN4/GDI1/ASAP1/CRMP1/RTN4/PPP3CA/NPR2/DUSP10/ID3/SEMA4F/MIB1/MIR199A2/IGF1/STAT3/MYLIP/NGEF/PRTG	57
BP	GO:0032680	regulation of tumor necrosis factor production	30/2306	160/18670	0.01252	0.07935	0.06105	ZC3H12A/TNFAIP3/RIPK2/HSPB1/IFIH1/IFNGR1/HLA-E/IRAK3/DDX58/CCL3/FADD/CYBA/THBS1/ZFP36/AKAP12/SIRPA/MC1R/ERRFI1/BCL3/AXL/WNT5A/AKAP8/HAVCR2/MIR125B1/TLR3/GAS6/PTPN11/TICAM1/IGF1/SASH3	30
BP	GO:0008585	female gonad development	20/2306	96/18670	0.01257	0.07946	0.06113	ICAM1/KIT/CEBPB/ARID5B/VEGFA/EREG/AFP/SLIT2/IDH1/LHX8/INHBB/SIRT1/BCL2L1/FZD4/EIF2B5/EIF2B4/PTX3/ZNF830/UBB/CYP19A1	20
BP	GO:1990823	response to leukemia inhibitory factor	20/2306	96/18670	0.01257	0.07946	0.06113	GFPT2/ICAM1/MSC/JARID2/EIF4A2/ARID5B/MAT2A/HK2/SOCS3/TRIM25/KLF4/BCLAF1/SMARCA5/SIRT1/EPS8/FZD4/NUP35/BCAT2/RFX2/SNX10	20
BP	GO:1990830	cellular response to leukemia inhibitory factor	20/2306	96/18670	0.01257	0.07946	0.06113	GFPT2/ICAM1/MSC/JARID2/EIF4A2/ARID5B/MAT2A/HK2/SOCS3/TRIM25/KLF4/BCLAF1/SMARCA5/SIRT1/EPS8/FZD4/NUP35/BCAT2/RFX2/SNX10	20
BP	GO:0061005	cell differentiation involved in kidney development	13/2306	54/18670	0.01263	0.07972	0.06134	LIF/BASP1/STAT1/BMP4/WWTR1/MYO1E/PODXL/YAP1/MMP9/MEF2C/GATA3/LGR4/OSR1	13
BP	GO:1904375	regulation of protein localization to cell periphery	23/2306	115/18670	0.01279	0.08066	0.06206	PID1/DAB2/SQSTM1/NKD2/PPFIA1/GPC4/STX3/GBP1/CLTC/GPSM2/RAB11FIP2/CLIP3/CDK5/STAC/ARF6/BCL2L1/MRAP2/ACTB/TNF/GRIPAP1/RER1/PICALM/EPB41L2	23
BP	GO:0050867	positive regulation of cell activation	64/2306	394/18670	0.01298	0.08098	0.06231	NFKBIZ/CCL5/IL6/CD70/VCAM1/MAP3K8/IL1B/CD83/RIPK2/IL33/CCL2/TNFSF9/IL7R/PDPN/TNFRSF14/PDCD1LG2/IL6ST/TNFSF13B/PAK1/PDGFRB/HLA-E/IL12A/MYB/IL4R/SOCS1/HLA-F/CD40/FYN/CCL3/SNX4/FADD/SLC39A10/THBS1/IL15/CYLD/ADA/EXOSC6/SIRPA/EBI3/CLCF1/STAT6/EFNB1/AXL/MEF2C/WNT5A/HAVCR2/STXBP1/CEBPA/GATA3/HLA-G/BCL10/DUSP10/GAS6/VAMP7/CDKN1A/PTPN11/NPPA/FGF10/TICAM1/CDC42/IGF1/SASH3/ADAM8/CBFB	64
BP	GO:0003176	aortic valve development	9/2306	32/18670	0.01299	0.08098	0.06231	TNFRSF1B/ROCK1/BMP4/SLIT2/BMPR2/SNAI2/ROBO1/GATA3/ROCK2	9
BP	GO:0003338	metanephros morphogenesis	9/2306	32/18670	0.01299	0.08098	0.06231	LIF/BASP1/STAT1/BMP4/PDGFRB/PKD2/HES5/LGR4/FGF10	9
BP	GO:0032814	regulation of natural killer cell activation	9/2306	32/18670	0.01299	0.08098	0.06231	HLA-E/IL12A/HLA-F/IL15/AXL/HAVCR2/PRDM1/GAS6/TICAM1	9
BP	GO:0035510	DNA dealkylation	9/2306	32/18670	0.01299	0.08098	0.06231	APOBEC3G/FTO/TET1/APOBEC3H/TET3/GATA3/APOBEC3F/USP9X/ASCC3	9
BP	GO:0060674	placenta blood vessel development	9/2306	32/18670	0.01299	0.08098	0.06231	PLCD3/PLCD1/SOCS3/NR2F2/PKD2/ITGB8/JUNB/RBM15/ARID1A	9
BP	GO:0007379	segment specification	6/2306	17/18670	0.01301	0.08098	0.06231	MAFB/IRX3/MEOX2/HES5/OSR1/DVL2	6
BP	GO:0031649	heat generation	6/2306	17/18670	0.01301	0.08098	0.06231	PTGS2/IL1B/IL1A/ARRDC3/ABAT/TNF	6
BP	GO:0035855	megakaryocyte development	6/2306	17/18670	0.01301	0.08098	0.06231	KIT/MEIS1/FLI1/PTPN11/PIP4K2A/WASF2	6
BP	GO:0042249	establishment of planar polarity of embryonic epithelium	6/2306	17/18670	0.01301	0.08098	0.06231	FZD1/FZD2/WNT5A/PTK7/DVL1/DVL2	6
BP	GO:0048535	lymph node development	6/2306	17/18670	0.01301	0.08098	0.06231	IL7R/PDPN/CD248/FADD/IL15/POLB	6
BP	GO:0050884	neuromuscular process controlling posture	6/2306	17/18670	0.01301	0.08098	0.06231	CNTNAP1/PNKD/GCH1/CLN8/ATP8A2/ADARB1	6
BP	GO:0090185	negative regulation of kidney development	6/2306	17/18670	0.01301	0.08098	0.06231	STAT1/BMP4/MMP9/TACSTD2/GATA3/OSR1	6
BP	GO:0048167	regulation of synaptic plasticity	34/2306	187/18670	0.01306	0.08105	0.06236	PTGS2/ADORA2A/KIT/SQSTM1/SIPA1L1/DBN1/GIP/PLK2/STX3/SSH1/EIF2AK4/RAB3GAP1/MAP1A/MEF2C/ITPKA/CDK5/ADORA1/KCNB1/SNAP47/RAB3A/SYT4/ARF1/DGKI/P2RX3/YWHAH/STAU1/DLG4/STXBP1/TSHZ3/NPTN/ABL1/YTHDF1/RIN1/PPFIA3	34
BP	GO:1905897	regulation of response to endoplasmic reticulum stress	18/2306	84/18670	0.01307	0.08105	0.06236	ERN1/PPP1R15A/FICD/HERPUD1/DNAJB9/NFE2L1/PMAIP1/GRINA/DNAJC3/SIRT1/BCL2L1/UBXN1/USP14/HYOU1/BRSK2/MAGEA3/TMEM33/BFAR	18
BP	GO:0034329	cell junction assembly	42/2306	241/18670	0.01307	0.08105	0.06236	CLDN1/FLNC/FSCN1/PRKCA/GJD3/CORO1C/VEGFA/ROCK1/RAB13/CNTNAP1/VCL/KRT14/LIMS2/THBS1/TRIP6/EPB41L3/ITGA2/SNAI2/GJB2/DUSP3/FLOT1/PHLDB2/ACTB/UGT8/TNF/ACTN4/FERMT2/PKP4/COL16A1/SDC4/ABL1/ROCK2/PKN2/CDC42/TJP1/CDH4/ITGA6/ACTG1/TLN1/PDCD6IP/NPHP1/CBFB	42
BP	GO:0002696	positive regulation of leukocyte activation	62/2306	380/18670	0.01308	0.08105	0.06236	NFKBIZ/CCL5/IL6/CD70/VCAM1/MAP3K8/IL1B/CD83/RIPK2/IL33/CCL2/TNFSF9/IL7R/TNFRSF14/PDCD1LG2/IL6ST/TNFSF13B/PAK1/HLA-E/IL12A/MYB/IL4R/SOCS1/HLA-F/CD40/FYN/CCL3/SNX4/FADD/SLC39A10/THBS1/IL15/CYLD/ADA/EXOSC6/SIRPA/EBI3/CLCF1/STAT6/EFNB1/AXL/MEF2C/WNT5A/HAVCR2/STXBP1/CEBPA/GATA3/HLA-G/BCL10/DUSP10/GAS6/VAMP7/CDKN1A/PTPN11/NPPA/FGF10/TICAM1/CDC42/IGF1/SASH3/ADAM8/CBFB	62
BP	GO:0018212	peptidyl-tyrosine modification	60/2306	366/18670	0.01314	0.08139	0.06262	ICAM1/CCL5/IL6/CSF2/LIF/RIPK2/EHD4/PARP14/KIT/TNFRSF14/GPRC5A/IL6ST/VEGFA/EREG/TPST1/PDGFRB/IL12A/SOCS1/SOCS3/CD44/CD40/FYN/NEDD9/DYRK2/IL15/TGFA/ROR1/HBEGF/GHR/SEMA4D/PDGFD/ERRFI1/CLCF1/PARP9/AXL/MIR19B2/ADORA1/CAMKK2/HES5/TYK2/TNF/DLG4/IL12RB2/FRK/PDGFC/SPINK1/PRKCD/ABL1/CLK4/GAS6/PTPN11/EPHA1/FGF10/ROS1/IGF1/CBLB/STAT3/ARL2BP/DVL2/ADRA2A	60
BP	GO:0010827	regulation of glucose transmembrane transport	17/2306	78/18670	0.01322	0.08145	0.06267	PID1/IL1B/C3/SLC2A1/HK2/GIP/IRS1/TRIB3/EDN1/ENPP1/ADIPOR2/CLIP3/TNF/APPL2/PTPN11/IGF1/SIRT6	17
BP	GO:0043407	negative regulation of MAP kinase activity	17/2306	78/18670	0.01322	0.08145	0.06267	IL1B/DUSP6/DNAJA1/BMP4/DUSP14/IRAK3/RGS2/SPRY1/DUSP3/RGS4/DUSP16/PRKCD/DUSP18/DUSP10/DUSP5/MIR218-1/ZNF675	17
BP	GO:0072171	mesonephric tubule morphogenesis	15/2306	66/18670	0.01322	0.08145	0.06267	BMP2/FGF2/SIX1/VEGFA/LZTS2/BMP4/PKD2/HOXA11/SIX4/PGF/TACSTD2/GATA3/HOXB7/LGR4/OSR1	15
BP	GO:1901991	negative regulation of mitotic cell cycle phase transition	43/2306	248/18670	0.01322	0.08145	0.06267	PSME2/CCL2/PSMA6/CDK6/PSMB10/FHL1/PSMB8/PSMB7/PSME1/PLK2/PSMB9/RPA2/PKD2/CCND1/KLF4/PSMA3/PRMT1/ZFP36L2/MAD1L1/GJC2/CARM1/PSMA1/PSMB2/CDKN2C/MIR19B2/BTG2/PSMB3/MIR137/ARID3A/CNOT8/PSMA8/ZNF830/CDK2AP2/CTDSP2/ZFYVE19/CDKN1A/PSME4/TFDP1/PSMB5/PSMG2/TAOK1/FOXO4/PSMF1	43
BP	GO:0001676	long-chain fatty acid metabolic process	22/2306	109/18670	0.01323	0.08145	0.06267	PTGS2/PTGES/SLC27A3/PLA2G4A/ELOVL5/AIG1/PLA2G4C/CYP2U1/CPT1A/ACSL5/CYP1A2/ELOVL2/ABCD1/DAGLA/DAGLB/ACOT8/SCP2/PTGS1/FAAH2/CYP2C19/CYP2S1/ELOVL3	22
BP	GO:0051149	positive regulation of muscle cell differentiation	22/2306	109/18670	0.01323	0.08145	0.06267	SOD2/KIT/BMP4/IL4R/SMARCD3/EDN1/CXCL9/MORF4L2/FLOT1/EHD1/MEF2C/SIRT1/MIR19B2/GDF15/MIR1-2/MIR125B1/ABL1/ENG/CDC42/MIR199A2/IGF1/CAPN2	22
BP	GO:0021762	substantia nigra development	11/2306	43/18670	0.01333	0.08179	0.06292	BASP1/CALM1/GLUD1/MBP/SYPL2/GNB4/ACTB/YWHAH/DYNLL1/CALM2/CDC42	11
BP	GO:0033173	calcineurin-NFAT signaling cascade	11/2306	43/18670	0.01333	0.08179	0.06292	PPP3CC/FHL2/DYRK2/LMCD1/RCAN1/TNF/PPP3CA/RCAN2/IGF1/HOMER2/CHP2	11
BP	GO:0042088	T-helper 1 type immune response	11/2306	43/18670	0.01333	0.08179	0.06292	IL1B/RELB/RIPK2/IL33/IL12A/IL18R1/IL4R/EBI3/STAT6/BCL3/HAVCR2	11
BP	GO:0000188	inactivation of MAPK activity	8/2306	27/18670	0.01362	0.08303	0.06388	DUSP6/DUSP14/DUSP3/RGS4/DUSP16/DUSP18/DUSP10/DUSP5	8
BP	GO:0039528	cytoplasmic pattern recognition receptor signaling pathway in response to virus	8/2306	27/18670	0.01362	0.08303	0.06388	BIRC3/IFIH1/BIRC2/DDX60/IRF7/TSPAN6/DDX58/DHX58	8
BP	GO:0051953	negative regulation of amine transport	8/2306	27/18670	0.01362	0.08303	0.06388	ARL6IP5/RGS2/RGS4/ADORA1/SYT4/ABAT/OSR1/ADRA2A	8
BP	GO:0007229	integrin-mediated signaling pathway	21/2306	103/18670	0.01366	0.08303	0.06388	ITGA1/ISG15/NEDD9/ITGB5/LIMS2/ITGA4/ITGB8/ITGA2/ITGA11/FERMT2/COL16A1/ZYX/ABL1/ITGAE/PTPN11/CDC42/FERMT1/MYH9/ITGA6/TLN1/ITGBL1	21
BP	GO:0002703	regulation of leukocyte mediated immunity	36/2306	201/18670	0.01368	0.08303	0.06388	CXCL6/IL6/IL1B/IL7R/RSAD2/C3/TNFRSF1B/HLA-E/IL12A/IL18R1/IL4R/HLA-F/CD40/DDX58/SNX4/FADD/HLA-A/EXOSC6/CLCF1/STAT6/TRAF2/MICB/HAVCR2/TNF/STXBP1/TLR3/GATA3/HLA-G/NCR1/VAMP7/NPPA/TICAM1/P2RX7/HLA-B/SASH3/HLA-H	36
BP	GO:0022408	negative regulation of cell-cell adhesion	33/2306	181/18670	0.01376	0.08303	0.06388	BMP2/ZC3H12A/ADORA2A/IRF1/CEBPB/C1QTNF1/TNFRSF14/PDCD1LG2/IDO1/VEGFA/BMP4/IL4R/SOCS1/LRRC32/MYADM/KLF4/UBASH3B/RDX/MBP/PODXL/MAD1L1/SNAI2/DUSP3/ABAT/HAVCR2/ASS1/PRKCD/HLA-G/SDC4/ABL1/PDE5A/AKNA/CBFB	33
BP	GO:0051147	regulation of muscle cell differentiation	33/2306	181/18670	0.01376	0.08303	0.06388	SOD2/BMP2/CXCL10/KIT/EREG/CFLAR/BMP4/PAK1/IL4R/SMARCD3/EDN1/CXCL9/DMPK/RGS2/MORF4L2/FLOT1/EHD1/MEF2C/SIRT1/MIR19B2/RGS4/GDF15/MIR1-2/MIR125B1/ABL1/ENG/SIK1/CDC42/MIR199A2/IGF1/FZD7/FOXO4/CAPN2	33
BP	GO:0002792	negative regulation of peptide secretion	28/2306	148/18670	0.01376	0.08303	0.06388	ZC3H12A/TNFAIP3/IL1B/IL33/RSAD2/LRRC32/IRS1/GBP1/RHBDF2/HADH/INHBB/F2R/SERGEF/SRGN/KCNB1/ANXA4/SYT4/TNF/SYTL4/SERPINB1/PPP3CA/LGR4/RAB11FIP1/GAS6/PTPN11/PYDC2/MAPKBP1/ADRA2A	28
BP	GO:0035148	tube formation	28/2306	148/18670	0.01376	0.08303	0.06388	SIX1/VEGFA/BMP4/FZD1/IRX3/SHROOM3/STK4/FZD2/PODXL/TGFB2/CEP290/SIX4/WNT5A/HES5/PTK7/GATA3/ARID1A/SDC4/ABL1/BCL10/RALA/FGF10/MIB1/DVL1/OSR1/DVL2/ATOH8/NFIB	28
BP	GO:0051592	response to calcium ion	28/2306	148/18670	0.01376	0.08303	0.06388	SLC25A24/PTGES/EEF2K/ANXA11/PPIF/CALM1/CAMK2D/PKD2/CCND1/THBS1/EDN1/TRPC1/CPNE3/MEF2C/JUNB/WNT5A/SYT4/CALM2/SPARC/STIM1/GDI1/SYT1/PPP3CA/MCOLN1/MNAT1/P2RX7/NEDD4/CHP2	28
BP	GO:0001759	organ induction	7/2306	22/18670	0.01376	0.08303	0.06388	BMP2/SIX1/BMP4/HOXA11/SPRY1/ROBO1/FGF10	7
BP	GO:0006925	inflammatory cell apoptotic process	7/2306	22/18670	0.01376	0.08303	0.06388	CCL5/IL6/PIK3CD/SLC7A11/IRF7/MEF2C/SIRT1	7
BP	GO:0010842	retina layer formation	7/2306	22/18670	0.01376	0.08303	0.06388	AHI1/HIPK2/FJX1/TOPORS/PTPRM/ATP8A2/RDH13	7
BP	GO:0036119	response to platelet-derived growth factor	7/2306	22/18670	0.01376	0.08303	0.06388	PDGFRB/FYN/RDX/PDGFD/ERRFI1/HAS2/HAS1	7
BP	GO:0051457	maintenance of protein location in nucleus	7/2306	22/18670	0.01376	0.08303	0.06388	BCL3/CDK5/TXN/TOPORS/SP100/ARL2BP/MORC3	7
BP	GO:0071379	cellular response to prostaglandin stimulus	7/2306	22/18670	0.01376	0.08303	0.06388	PTGFR/PTGER2/ACACA/AKAP8/TNC/PPARG/GNG2	7
BP	GO:0090189	regulation of branching involved in ureteric bud morphogenesis	7/2306	22/18670	0.01376	0.08303	0.06388	SIX1/VEGFA/BMP4/SIX4/TACSTD2/HOXB7/LGR4	7
BP	GO:0030010	establishment of cell polarity	26/2306	135/18670	0.01377	0.08303	0.06388	CYTH3/FSCN1/ROCK1/PAK1/JAM3/WWC1/RUFY3/GPSM2/DCTN1/RAB11FIP2/SPRY1/AMOTL1/WNT5A/MYO18A/ARF6/HES5/GSN/PTK7/BRSK2/GATA3/ROCK2/FGF10/CDC42/FERMT1/MYH9/CRKL	26
BP	GO:0034330	cell junction organization	49/2306	290/18670	0.01382	0.08308	0.06392	CLDN1/FLNC/FSCN1/PRKCA/GJD3/CORO1C/VEGFA/ROCK1/RAB13/CNTNAP1/VCL/KRT14/IQSEC1/LIMS2/THBS1/TRIP6/RDX/EPB41L3/F2R/TGFB2/ITGA2/SNAI2/GJB2/DUSP3/FLOT1/PHLDB2/ARF6/ACTB/UGT8/TNF/ACTN4/FERMT2/NUMBL/PKP4/COL16A1/SDC4/MAPRE2/ABL1/ROCK2/PKN2/CDC42/TJP1/CDH4/ITGA6/ACTG1/TLN1/PDCD6IP/NPHP1/CBFB	49
BP	GO:0009755	hormone-mediated signaling pathway	41/2306	235/18670	0.01382	0.08308	0.06392	PPARGC1A/DAB2/PGRMC2/DAXX/DNAJA1/BMP4/PAK1/RXRA/NR2F2/LATS2/RNF14/FHL2/LBH/UBR5/ARNTL/THRA/YAP1/ADIPOR2/CARM1/VDR/SIRT1/NKX3-1/TP63/DDX5/RNF4/YWHAH/APPL2/KCTD6/GPAM/ARID1A/LGR4/UFSP2/NCOR2/PER1/PPARG/PTPN11/CDK7/NEDD4/TADA3/NCOA6/CBFB	41
BP	GO:0060560	developmental growth involved in morphogenesis	41/2306	235/18670	0.01382	0.08308	0.06392	CSF1/NTN1/ZFYVE27/SIX1/DBN1/AUTS2/VEGFA/LZTS2/BMP4/PAK1/VCL/RDH10/SLIT2/BMPR2/RUFY3/ITGA4/EIF2AK4/SEMA4D/SPRY1/YAP1/IFRD1/SIX4/CDK5/WNT5A/SYT4/TNC/PTK7/BIN3/FLRT3/GDI1/SYT1/RTN4/ABL1/FGF10/SEMA4F/CDH4/DVL1/TMEM108/RAPH1/USP9X/SIRT6	41
BP	GO:0001657	ureteric bud development	20/2306	97/18670	0.01405	0.0844	0.06494	BMP2/BASP1/FGF2/SIX1/VEGFA/LZTS2/BMP4/SLIT2/PKD2/HOXA11/BMPER/SPRY1/SIX4/PGF/TACSTD2/GATA3/HOXB7/SDC4/LGR4/OSR1	20
BP	GO:0002220	innate immune response activating cell surface receptor signaling pathway	23/2306	116/18670	0.01414	0.0847	0.06517	PSME2/RELB/NFKB1/PSMA6/PSMB10/PSMB8/PSMB7/PSME1/PAK1/PSMB9/FYN/PSMA3/PSMA1/PSMB2/PSMB3/PRKCD/PSMA8/BCL10/MUC15/MUC17/PSME4/PSMB5/PSMF1	23
BP	GO:0034219	carbohydrate transmembrane transport	23/2306	116/18670	0.01414	0.0847	0.06517	PID1/IL1B/SLC2A6/C3/SLC2A1/HK2/GIP/SORT1/IRS1/TMEM144/TRIB3/EDN1/ENPP1/SLC2A12/ADIPOR2/CLIP3/SESN2/TNF/APPL2/PTPN11/IGF1/SLC2A10/SIRT6	23
BP	GO:0010712	regulation of collagen metabolic process	12/2306	49/18670	0.01417	0.0847	0.06517	IL6/BMP4/PDGFRB/MYB/F2R/ITGA2/ERRFI1/CYGB/PPARG/ENG/MIR218-1/SERPINF2	12
BP	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	12/2306	49/18670	0.01417	0.0847	0.06517	ZC3H12A/TNFAIP3/TNIP1/TNIP3/STAT1/SIRPA/SIRT1/OPTN/ABL1/PER1/TLE1/MAPKBP1	12
BP	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	12/2306	49/18670	0.01417	0.0847	0.06517	BID/G0S2/PPP2R1B/FADD/THBS1/CYLD/STK4/PMAIP1/DEDD2/TRAF2/RBCK1/BCL10	12
BP	GO:0003206	cardiac chamber morphogenesis	25/2306	129/18670	0.01437	0.08583	0.06604	ID2/CITED2/BMP4/FZD1/RXRA/SLIT2/BMPR2/SMARCD3/DHRS3/MSX2/FGFRL1/FZD2/TGFB2/GATA6/ROBO1/MEF2C/WNT5A/MIR1-2/RBM15/FKBP1A/GATA3/MYH6/ENG/UBE4B/TBX3	25
BP	GO:0048814	regulation of dendrite morphogenesis	19/2306	91/18670	0.01441	0.08597	0.06615	SIPA1L1/DBN1/CAPRIN1/EEF2K/NEUROG3/SEMA4D/SDC2/HECW2/ITPKA/CDK5/BHLHB9/PDLIM5/YWHAH/PPP3CA/VAMP7/ACTR2/NEDD4/NGEF/ANKRD27	19
BP	GO:0032350	regulation of hormone metabolic process	10/2306	38/18670	0.01466	0.08715	0.06705	BMP2/IL1B/NFKB1/PPARGC1A/RDH10/CYP27B1/TCF7L2/VDR/TNF/GATA3	10
BP	GO:0035329	hippo signaling	10/2306	38/18670	0.01466	0.08715	0.06705	WWTR1/WWC1/LATS2/WTIP/STK4/YAP1/AMOTL1/PJA2/TJP1/DVL2	10
BP	GO:1904037	positive regulation of epithelial cell apoptotic process	10/2306	38/18670	0.01466	0.08715	0.06705	IL6/CCL2/PPARGC1A/CD248/CD40/SORT1/ITGA4/THBS1/GSN/HLA-G	10
BP	GO:0006024	glycosaminoglycan biosynthetic process	22/2306	110/18670	0.01467	0.08715	0.06705	IL1B/ST3GAL1/NFKB1/PDGFRB/GPC4/B4GALT3/VCAN/CHST7/HSPG2/CLTC/SDC2/CSGALNACT1/HAS2/CSGALNACT2/GALNT5/HAS1/HAS3/EXT1/ST3GAL3/SDC4/HS2ST1/ST3GAL4	22
BP	GO:0006575	cellular modified amino acid metabolic process	36/2306	202/18670	0.01472	0.0874	0.06724	PTGES/OSBPL10/DIO2/PLSCR1/MTHFD2L/SLC7A11/PLA2G4A/SLC22A4/GSTA4/NFE2L1/IDH1/GCH1/CROT/P4HA2/EGLN1/PCYOX1/MTHFD2/CPT1A/PLOD2/CHAC2/GAMT/HAGH/PLA2G12A/ALDH7A1/OSBPL5/ASS1/BHMT2/ALDH5A1/GATA3/GLRX2/CNDP2/SLC19A1/ALDH1L2/MGST2/GNMT/ACADM	36
BP	GO:0007032	endosome organization	17/2306	79/18670	0.01496	0.0886	0.06817	CHMP1B/SQSTM1/CORO1C/PLEKHF1/CHMP4B/STX6/ANXA8/VPS37D/VPS36/VPS37C/HOOK3/CHMP5/PI4K2B/AKTIP/PDCD6IP/SNX3/SNX10	17
BP	GO:0050773	regulation of dendrite development	28/2306	149/18670	0.01501	0.0886	0.06817	SIPA1L1/DBN1/CAPRIN1/EEF2K/PLK2/NEUROG3/SEMA4D/SDC2/LPAR1/HECW2/CARM1/MEF2C/ITPKA/CDK5/ARF6/BHLHB9/ARF1/PDLIM5/YWHAH/TMEM106B/ASAP1/PPP3CA/VAMP7/ACTR2/NEDD4/NGEF/ANKRD27/CRKL	28
BP	GO:0016266	O-glycan processing	14/2306	61/18670	0.01502	0.0886	0.06817	ST3GAL1/GALNT10/GXYLT1/POMGNT1/GALNT5/GCNT1/C1GALT1/ST3GAL3/GALNT4/MUC15/MUC17/GALNT11/GALNT1/ST3GAL4	14
BP	GO:0032233	positive regulation of actin filament bundle assembly	14/2306	61/18670	0.01502	0.0886	0.06817	ARHGEF10/PAK1/PXN/LPAR1/FHOD1/PFN2/ARHGEF5/SH3PXD2B/SDC4/ABL1/ROCK2/EPHA1/CDC42/SERPINF2	14
BP	GO:0045123	cellular extravasation	14/2306	61/18670	0.01502	0.0886	0.06817	ICAM1/VCAM1/ITGA1/CCL2/PIK3CD/ROCK1/FADD/ITGA4/PDGFD/SIRPA/TNF/GCNT1/ADAM8/CRKL	14
BP	GO:0045604	regulation of epidermal cell differentiation	14/2306	61/18670	0.01502	0.0886	0.06817	MAFF/ROCK1/BMP4/MAFG/ZFP36/MSX2/CYP27B1/ERRFI1/VDR/TP63/HES5/ROCK2/SULT2B1/CBFB	14
BP	GO:0050701	interleukin-1 secretion	14/2306	61/18670	0.01502	0.0886	0.06817	ZC3H12A/TNFAIP3/RIPK2/ABCA1/PANX1/GBP5/PANX2/CCL3/GSDMD/WNT5A/SERPINB1/GAS6/PYDC2/P2RX7	14
BP	GO:0000281	mitotic cytokinesis	16/2306	73/18670	0.01511	0.08901	0.06848	CHMP1B/ROCK1/LZTS2/CHMP4B/ANK3/SON/RHOB/KLHDC8B/KIF4B/ARF1/BIN3/CHMP5/ROCK2/MITD1/MYH10/PDCD6IP	16
BP	GO:0060538	skeletal muscle organ development	31/2306	169/18670	0.01525	0.08978	0.06908	MAFF/MSC/PITX1/BASP1/SIX1/CFLAR/POPDC2/SAP30/NR2F2/FGFRL1/MYOM1/ARNTL/SRPK3/HOXD9/FLNB/FLOT1/MEOX2/SIX4/MEF2C/AKIRIN1/CDK5/BTG2/DDX5/BIN3/ASS1/MIR1-2/PPP3CA/ASB2/CASQ1/DNER/VAMP5	31
BP	GO:0031346	positive regulation of cell projection organization	62/2306	383/18670	0.01531	0.09	0.06925	FSCN1/KIT/NTN1/FNBP1L/ZFYVE27/DBN1/CAPRIN1/CORO1C/AUTS2/VEGFA/EEF2K/CFLAR/PAK1/CDC42EP1/FZD1/FYN/CDC42EP3/SLIT2/BMPR2/RUFY3/KIDINS220/CCDC88A/DPYSL3/SEMA4D/RGS2/ITGA2/LPAR1/ROBO1/ITPKA/ATF1/AKIRIN1/ARPC2/WNT5A/BHLHB9/SYT4/ARF1/EPS8/PTK7/DYNLL1/PLEK2/FZD4/DLG4/ATP8A2/PLXND1/TMEM106B/GDI1/SYT1/NPTN/MARK4/RALA/VAMP7/ACTR2/MNS1/CDC42/CDH4/ITGA6/DVL1/DVL2/P2RX7/ANKRD27/WASF2/SNX3	62
BP	GO:0002761	regulation of myeloid leukocyte differentiation	23/2306	117/18670	0.0156	0.09031	0.06948	LIF/ID2/TRIB1/CDK6/CSF1/CEBPB/PRKCA/MAFB/IRF7/CCL3/FADD/UBASH3B/MITF/TMEM64/ACIN1/FBN1/TNF/BGLAP/MIR125B1/TFE3/TLR3/PIAS3/ZNF675	23
BP	GO:0051153	regulation of striated muscle cell differentiation	23/2306	117/18670	0.0156	0.09031	0.06948	BMP2/CXCL10/CFLAR/BMP4/PAK1/IL4R/EDN1/CXCL9/DMPK/RGS2/MORF4L2/FLOT1/EHD1/MEF2C/MIR19B2/RGS4/GDF15/MIR1-2/SIK1/MIR199A2/IGF1/FZD7/CAPN2	23
BP	GO:0001973	adenosine receptor signaling pathway	5/2306	13/18670	0.01565	0.09031	0.06948	ADORA2A/P2RY11/ADA/ADORA1/ADORA3	5
BP	GO:0006703	estrogen biosynthetic process	5/2306	13/18670	0.01565	0.09031	0.06948	RDH8/DHRS11/HSD17B12/HSD17B7/CYP19A1	5
BP	GO:0014745	negative regulation of muscle adaptation	5/2306	13/18670	0.01565	0.09031	0.06948	FOXO1/KLF4/LMNA/ERRFI1/MIR214	5
BP	GO:0030497	fatty acid elongation	5/2306	13/18670	0.01565	0.09031	0.06948	ELOVL5/ELOVL7/ELOVL2/ABCD1/ELOVL3	5
BP	GO:0031650	regulation of heat generation	5/2306	13/18670	0.01565	0.09031	0.06948	PTGS2/IL1B/ARRDC3/ABAT/TNF	5
BP	GO:0032488	Cdc42 protein signal transduction	5/2306	13/18670	0.01565	0.09031	0.06948	ABCA1/NTN1/RHOU/ABL1/CDC42	5
BP	GO:0038065	collagen-activated signaling pathway	5/2306	13/18670	0.01565	0.09031	0.06948	COL1A1/UBASH3B/ITGA2/ITGA11/COL4A1	5
BP	GO:0042635	positive regulation of hair cycle	5/2306	13/18670	0.01565	0.09031	0.06948	MSX2/TGFB2/WNT5A/TNF/FST	5
BP	GO:0043201	response to leucine	5/2306	13/18670	0.01565	0.09031	0.06948	PPARGC1A/SESN1/SESN3/UBR1/SESN2	5
BP	GO:0045006	DNA deamination	5/2306	13/18670	0.01565	0.09031	0.06948	APOBEC3G/EXOSC6/APOBEC3H/CDADC1/APOBEC3F	5
BP	GO:0048711	positive regulation of astrocyte differentiation	5/2306	13/18670	0.01565	0.09031	0.06948	BMP2/LIF/ID2/IL6ST/CLCF1	5
BP	GO:0060100	positive regulation of phagocytosis, engulfment	5/2306	13/18670	0.01565	0.09031	0.06948	C3/ITGA2/APPL2/PPARG/RAB31	5
BP	GO:0060340	positive regulation of type I interferon-mediated signaling pathway	5/2306	13/18670	0.01565	0.09031	0.06948	IRF7/FADD/WNT5A/TRIM6/ZBP1	5
BP	GO:0060601	lateral sprouting from an epithelium	5/2306	13/18670	0.01565	0.09031	0.06948	BMP4/WNT5A/SULF1/TP63/FGF10	5
BP	GO:0060712	spongiotrophoblast layer development	5/2306	13/18670	0.01565	0.09031	0.06948	LIF/SOCS3/PHLDA2/ASCL2/BIRC6	5
BP	GO:1903960	negative regulation of anion transmembrane transport	5/2306	13/18670	0.01565	0.09031	0.06948	ARL6IP5/THBS1/RGS2/RGS4/OSR1	5
BP	GO:1905155	positive regulation of membrane invagination	5/2306	13/18670	0.01565	0.09031	0.06948	C3/ITGA2/APPL2/PPARG/RAB31	5
BP	GO:0072163	mesonephric epithelium development	20/2306	98/18670	0.01567	0.09031	0.06948	BMP2/BASP1/FGF2/SIX1/VEGFA/LZTS2/BMP4/SLIT2/PKD2/HOXA11/BMPER/SPRY1/SIX4/PGF/TACSTD2/GATA3/HOXB7/SDC4/LGR4/OSR1	20
BP	GO:0072164	mesonephric tubule development	20/2306	98/18670	0.01567	0.09031	0.06948	BMP2/BASP1/FGF2/SIX1/VEGFA/LZTS2/BMP4/SLIT2/PKD2/HOXA11/BMPER/SPRY1/SIX4/PGF/TACSTD2/GATA3/HOXB7/SDC4/LGR4/OSR1	20
BP	GO:0003231	cardiac ventricle development	25/2306	130/18670	0.01577	0.09083	0.06988	ID2/CITED2/BMP4/FZD1/RXRA/SLIT2/BMPR2/SMARCD3/FGFRL1/FZD2/TGFB2/HECTD1/ROBO1/MEF2C/WNT5A/PTK7/MIR1-2/RBM15/FKBP1A/GATA3/PRDM1/MYH6/ENG/UBE4B/TBX3	25
BP	GO:0007050	cell cycle arrest	41/2306	237/18670	0.01581	0.09096	0.06998	ID2/ERN1/CDK6/IRF1/PPP1R15A/PLK2/IL12A/PKD2/CCND1/THBS1/PRMT1/EIF2AK4/TCF7L2/CDC14B/PPP1R9B/TP53INP1/TGFB2/KAT2B/GATA6/ZFHX3/CARM1/CDKN2C/CDK5/NKX3-1/BTG2/CDKN1C/ARID3A/MLF1/CNOT8/PRKAB2/ABL1/SETMAR/GAS6/SLC25A33/CDKN1A/FGF10/RASSF1/TFDP1/CDK7/MYBBP1A/FOXO4	41
BP	GO:0035307	positive regulation of protein dephosphorylation	11/2306	44/18670	0.01584	0.09096	0.06998	ITGA1/PPP1R15A/PDGFRB/CALM1/PPP1R12A/SLC39A10/ADORA1/CALM2/PRKCD/ANKLE2/PPP1R7	11
BP	GO:1903573	negative regulation of response to endoplasmic reticulum stress	11/2306	44/18670	0.01584	0.09096	0.06998	PPP1R15A/HERPUD1/DNAJB9/GRINA/DNAJC3/BCL2L1/UBXN1/USP14/HYOU1/MAGEA3/BFAR	11
BP	GO:0010591	regulation of lamellipodium assembly	9/2306	33/18670	0.01595	0.09119	0.07016	FSCN1/AUTS2/SLIT2/AKIRIN1/ARPC2/BIN3/MIR214/CDC42/WASF2	9
BP	GO:0033028	myeloid cell apoptotic process	9/2306	33/18670	0.01595	0.09119	0.07016	CCL5/IL6/PIK3CD/SLC7A11/IRF7/THRA/MEF2C/SIRT1/ARF6	9
BP	GO:0042755	eating behavior	9/2306	33/18670	0.01595	0.09119	0.07016	ADORA2A/OXTR/CPT1A/GDF15/ATP8A2/IAPP/NMUR2/STAT3/RMI1	9
BP	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	9/2306	33/18670	0.01595	0.09119	0.07016	TNFAIP3/NR2F2/LATS2/KAT2B/HEXIM2/CDKN2C/CDKN1C/CEBPA/CDKN1A	9
BP	GO:0048536	spleen development	9/2306	33/18670	0.01595	0.09119	0.07016	NFKB2/CITED2/JARID2/FADD/POLB/BCL3/RBM15/ABL1/FGF10	9
BP	GO:0032640	tumor necrosis factor production	30/2306	163/18670	0.01605	0.09161	0.07048	ZC3H12A/TNFAIP3/RIPK2/HSPB1/IFIH1/IFNGR1/HLA-E/IRAK3/DDX58/CCL3/FADD/CYBA/THBS1/ZFP36/AKAP12/SIRPA/MC1R/ERRFI1/BCL3/AXL/WNT5A/AKAP8/HAVCR2/MIR125B1/TLR3/GAS6/PTPN11/TICAM1/IGF1/SASH3	30
BP	GO:0099173	postsynapse organization	30/2306	163/18670	0.01605	0.09161	0.07048	SIPA1L1/DBN1/CAPRIN1/SLC7A11/EEF2K/FYN/SSH1/ITPKA/CDK5/WNT5A/VPS35/ARF6/BHLHB9/ARF1/LHFPL4/ACTB/PDLIM5/CHRNB1/DLG4/LRFN4/ACTR2/CDC42/MYH10/DVL1/ACTG1/TMEM108/NGEF/CRKL/RER1/WASF2	30
BP	GO:0007163	establishment or maintenance of cell polarity	37/2306	210/18670	0.01609	0.09174	0.07058	CYTH3/FSCN1/ROCK1/PAK1/JAM3/ACTR3/WWC1/RHOJ/LMNA/RUFY3/GPSM2/RHOB/DCTN1/RAB11FIP2/SPRY1/LIN7A/RHOBTB3/RHOU/AMOTL1/WNT5A/MYO18A/ARF6/HES5/GSN/PTK7/BRSK2/CAP2/GATA3/ROCK2/ACTR2/FGF10/CDC42/FERMT1/MYH9/LIN7C/PDCD6IP/CRKL	37
BP	GO:0035710	CD4-positive, alpha-beta T cell activation	19/2306	92/18670	0.01612	0.09183	0.07065	NFKBIZ/ZC3H12A/IL6/RELB/CD83/RIPK2/SH3RF1/RSAD2/IL12A/IL18R1/MYB/IL4R/SOCS1/STAT6/BCL3/GATA3/STAT3/SASH3/CBFB	19
BP	GO:0018108	peptidyl-tyrosine phosphorylation	59/2306	363/18670	0.01633	0.09289	0.07147	ICAM1/CCL5/IL6/CSF2/LIF/RIPK2/EHD4/PARP14/KIT/TNFRSF14/GPRC5A/IL6ST/VEGFA/EREG/PDGFRB/IL12A/SOCS1/SOCS3/CD44/CD40/FYN/NEDD9/DYRK2/IL15/TGFA/ROR1/HBEGF/GHR/SEMA4D/PDGFD/ERRFI1/CLCF1/PARP9/AXL/MIR19B2/ADORA1/CAMKK2/HES5/TYK2/TNF/DLG4/IL12RB2/FRK/PDGFC/SPINK1/PRKCD/ABL1/CLK4/GAS6/PTPN11/EPHA1/FGF10/ROS1/IGF1/CBLB/STAT3/ARL2BP/DVL2/ADRA2A	59
BP	GO:0016331	morphogenesis of embryonic epithelium	28/2306	150/18670	0.01634	0.09289	0.07147	SIX1/ALDH1A3/BMP4/FZD1/RDH10/IRX3/SHROOM3/STK4/FZD2/TGFB2/SIX4/WNT5A/SULF1/TP63/HES5/PTK7/GATA3/ARID1A/SDC4/ABL1/BCL10/RALA/GRSF1/FGF10/MIB1/DVL1/OSR1/DVL2	28
BP	GO:0002683	negative regulation of immune system process	73/2306	463/18670	0.01646	0.09348	0.07192	NFKBIA/ZC3H12A/TNFAIP3/IL33/CCL2/ID2/TRIB1/ADORA2A/CDK6/IRF1/PARP14/CEBPB/MEIS1/IL7R/MAFB/TNFRSF14/PDCD1LG2/LPXN/IDO1/BMP4/HLA-E/IL4R/SOCS1/TSPAN6/HLA-F/IRAK3/SLIT2/LRRC32/CCL3/ADAR/FADD/GBP1/ITCH/THBS1/ZFP36/UBASH3B/ADA/PRMT1/DHX58/MAD1L1/TGFB2/KLF13/STAT6/DUSP3/PSMA1/AXL/ADORA1/HES5/MICB/FBN1/HAVCR2/TNF/SLAMF8/RBM15/TRAFD1/MIR125B1/HOXA9/CNR2/PVRIG/TLR3/HLA-G/SDC4/LGR4/BCL10/DUSP10/PPARG/TICAM1/PDE5A/TRIM38/PIAS3/CYP19A1/ZNF675/CBFB	73
BP	GO:0046717	acid secretion	24/2306	124/18670	0.01647	0.09348	0.07192	IL1B/BDKRB2/ADORA2A/GLS/PLA2G4A/AQP9/SLC38A2/PPFIA1/OXTR/EDN1/RAB3GAP1/PLA2G12A/ABCC2/ADORA1/RAB3A/SYT4/ABAT/STXBP1/GRM2/SYT1/NMUR2/P2RX7/PPFIA3/SNX10	24
BP	GO:0001776	leukocyte homeostasis	18/2306	86/18670	0.01653	0.09372	0.0721	CXCL6/TNFAIP3/IL6/PIK3CD/SLC7A11/TNFSF13B/JAM3/FADD/ADA/PMAIP1/AXL/MEF2C/CACNA1F/BAP1/ABL1/BCL10/PDE4B/P2RX7	18
BP	GO:0002931	response to ischemia	12/2306	50/18670	0.01661	0.09391	0.07225	PPARGC1A/CSF1/SQSTM1/PANX1/EEF2K/HK2/PPIF/PANX2/GJB2/HYOU1/ROCK2/P2RX7	12
BP	GO:1903793	positive regulation of anion transport	12/2306	50/18670	0.01661	0.09391	0.07225	IL1B/ADORA2A/CEBPB/FABP3/EDN1/RAB3GAP1/SYT4/ABAT/ATP8A2/STXBP1/PRKCD/P2RX7	12
BP	GO:2000725	regulation of cardiac muscle cell differentiation	12/2306	50/18670	0.01661	0.09391	0.07225	BMP2/BMP4/PAK1/EDN1/RGS2/MEF2C/MIR19B2/RGS4/MIR1-2/MIR199A2/IGF1/FZD7	12
BP	GO:0050727	regulation of inflammatory response	76/2306	485/18670	0.01677	0.09476	0.07291	NFKBIZ/NFKBIA/BIRC3/ZC3H12A/TNFAIP3/CCL5/PTGS2/IL6/TNIP1/IL1B/TNFAIP6/SLC7A2/IL33/NFKB1/PSMA6/ADORA2A/MMP3/C2CD4B/CEBPB/BIRC2/OSMR/C3/TNFRSF1B/IDO1/IL6ST/GBP5/HLA-E/CCL3L3/SOCS3/ETS1/NFE2L1/KLF4/CCL3/SNX4/IL15/CYLD/ADA/IL17RB/MAPK13/SIRPA/ADCY7/CCL1/ITGA2/ABCC1/MMP9/PSMA1/ABCD1/SIGLEC10/WNT5A/ADORA1/VPS35/CFB/TNF/SLAMF8/APPL2/BAP1/CNR2/TLR3/CEBPA/GATA3/PRKCD/ZYX/SERPINE1/DUSP10/USP18/PER1/VAMP7/PPARG/PYDC2/NPPA/TICAM1/MGST2/IGF1/ADAM8/CYP19A1/AKNA	76
BP	GO:0015748	organophosphate ester transport	21/2306	105/18670	0.01683	0.09489	0.07301	SLC25A24/KCNN4/OSBPL10/ABCA1/PITPNC1/ATP8B1/ABCC1/PLEKHA3/ABCD1/TNFAIP8L3/OSBPL5/ATP8A2/PRKCD/SLC25A33/SCP2/P2RX7/SLC37A1/SLC25A36/TMEM30B/STARD7/ABCC11	21
BP	GO:0045185	maintenance of protein location	21/2306	105/18670	0.01683	0.09489	0.07301	NFKBIA/NFKBIE/DBN1/HK2/PKD2/ANK3/EPB41L3/FLNB/BCL3/CDK5/SRGN/TXN/FBN1/GSN/TOPORS/SP100/ARL2BP/SRI/TLN1/RER1/MORC3	21
BP	GO:0043271	negative regulation of ion transport	29/2306	157/18670	0.01689	0.09516	0.07321	ICAM1/PTGS2/GSTO1/RRAD/PPIF/CALM1/CAMK2D/ARL6IP5/PKD2/ANK3/THBS1/THADA/RGS2/HECW2/MMP9/GEM/RGS4/ADORA1/CRBN/SLC30A1/ABAT/CALM2/PXK/MIR1-2/SPINK1/OSR1/SRI/NEDD4/ADRA2A	29
BP	GO:0033598	mammary gland epithelial cell proliferation	8/2306	28/18670	0.01705	0.09562	0.07357	ID2/CEBPB/CCND1/STAT6/ROBO1/WNT5A/GATA3/RTN4	8
BP	GO:0035116	embryonic hindlimb morphogenesis	8/2306	28/18670	0.01705	0.09562	0.07357	PITX1/BMP4/MSX2/TP63/OSR2/RSPO2/OSR1/TBX3	8
BP	GO:0036296	response to increased oxygen levels	8/2306	28/18670	0.01705	0.09562	0.07357	FOXO1/PDGFRB/COL1A1/FAS/POLB/ATG7/PPARG/CDKN1A	8
BP	GO:0042634	regulation of hair cycle	8/2306	28/18670	0.01705	0.09562	0.07357	MSX2/ARNTL/TGFB2/WNT5A/TNF/FST/PER1/FERMT1	8
BP	GO:0060512	prostate gland morphogenesis	8/2306	28/18670	0.01705	0.09562	0.07357	BMP4/RXRA/WNT5A/NKX3-1/SULF1/TP63/TNC/FGF10	8
BP	GO:0005977	glycogen metabolic process	16/2306	74/18670	0.01713	0.09572	0.07364	PYGL/IL6ST/PPP1R3F/UGP2/CALM1/IRS1/PGM2L1/DYRK2/PHLDA2/ENPP1/PHKB/GYG1/GYS2/PHKA2/IGF1/GNMT	16
BP	GO:0014015	positive regulation of gliogenesis	16/2306	74/18670	0.01713	0.09572	0.07364	BMP2/IL6/IL1B/LIF/ID2/CSF1/TNFRSF1B/IL6ST/MYB/CCL3/GJC2/CLCF1/TNF/MIR125B1/PPARG/CRKL	16
BP	GO:0051145	smooth muscle cell differentiation	16/2306	74/18670	0.01713	0.09572	0.07364	SOD2/KIT/SIX1/VEGFA/EREG/BMP4/SMARCD3/GATA6/MEF2C/SIRT1/MIR1-2/MIR125B1/ENG/FGF10/SGCB/FOXO4	16
BP	GO:0060998	regulation of dendritic spine development	16/2306	74/18670	0.01713	0.09572	0.07364	SIPA1L1/DBN1/CAPRIN1/EEF2K/PLK2/LPAR1/MEF2C/ITPKA/CDK5/ARF6/BHLHB9/ARF1/PDLIM5/ASAP1/ACTR2/NGEF	16
BP	GO:0032835	glomerulus development	14/2306	62/18670	0.01726	0.09629	0.07408	BASP1/PLCE1/CFLAR/BMP4/PDGFRB/WWTR1/SULF2/MYO1E/PODXL/PDGFD/MEF2C/SULF1/LGR4/OSR1	14
BP	GO:0032922	circadian regulation of gene expression	14/2306	62/18670	0.01726	0.09629	0.07408	NAMPT/RELB/ID2/PPARGC1A/AHR/NPAS2/ARNTL/CSNK1E/ZFHX3/SIRT1/LGR4/PER1/MYCBP2/MYBBP1A	14
BP	GO:0043409	negative regulation of MAPK cascade	33/2306	184/18670	0.01731	0.09632	0.0741	TNIP1/IL1B/LIF/CNKSR3/FOXO1/DUSP6/DNAJA1/BMP4/DUSP14/IRAK3/KLF4/GBP1/ITCH/PIK3R2/CYLD/SIRPA/RGS2/SPRY1/ERRFI1/DUSP3/RGS4/RNF149/DUSP16/PRKCD/ABL1/DUSP18/DUSP10/PER1/DUSP5/SH3RF2/MIR218-1/P2RX7/ZNF675	33
BP	GO:0046486	glycerolipid metabolic process	66/2306	414/18670	0.01739	0.09632	0.0741	GK/PLD1/OSBPL10/LPIN1/FGF2/PIK3CD/GPD1L/PLCE1/PLSCR1/C3/INSIG2/PLA2G4A/PDGFRB/SLC22A4/SOCS1/SOCS3/RAB38/FABP3/PISD/PLA2G4C/PIGV/DBI/PIK3R2/PTPN13/LIPG/CPT1A/PIK3R3/IMPA2/RAB4A/PLEKHA3/CPNE3/DAGLA/EFR3A/PLA2G12A/SIRT1/RGN/ARF1/OSBPL5/ARF3/DGKI/DAGLB/ABHD5/SOCS2/ALDH5A1/ABHD3/GPAM/MPPE1/INPP5B/CPS1/PIGK/PIGS/PTPN11/CHKB/IP6K3/PIP4K2A/FAR1/SIK1/INPP1/PI4K2B/SH3YL1/TBL1XR1/SBF1/PLEKHA4/CAPN2/LCLAT1/STARD7	66
BP	GO:0006633	fatty acid biosynthetic process	30/2306	164/18670	0.0174	0.09632	0.0741	PTGS2/IL1B/PTGES/INSIG2/GIP/ACACB/ELOVL5/SCD/ELOVL7/TRIB3/EDN1/LIPG/ACACA/CYP1A2/CBR4/ADIPOR2/ELOVL2/ABCD1/NDUFAB1/SIRT1/RGN/HSD17B12/DECR2/ABHD3/PRKAB2/PECR/PTGS1/MID1IP1/FADS3/ELOVL3	30
BP	GO:0010612	regulation of cardiac muscle adaptation	6/2306	18/18670	0.01752	0.09632	0.0741	FOXO1/LMNA/ERRFI1/PPP3CA/MIR214/MIR199A2	6
BP	GO:0044320	cellular response to leptin stimulus	6/2306	18/18670	0.01752	0.09632	0.0741	PID1/UGCG/INHBB/BBS2/SIRT1/STAT3	6
BP	GO:0048739	cardiac muscle fiber development	6/2306	18/18670	0.01752	0.09632	0.0741	VEGFA/BMP4/MYOM1/SGCD/MYOM3/MYH6	6
BP	GO:0051023	regulation of immunoglobulin secretion	6/2306	18/18670	0.01752	0.09632	0.0741	IL6/IL33/HLA-E/CD40/TRAF2/TNF	6
BP	GO:0051957	positive regulation of amino acid transport	6/2306	18/18670	0.01752	0.09632	0.0741	ADORA2A/RAB3GAP1/SYT4/ABAT/STXBP1/P2RX7	6
BP	GO:0060546	negative regulation of necroptotic process	6/2306	18/18670	0.01752	0.09632	0.0741	BIRC3/BIRC2/CFLAR/FADD/RBCK1/MIR214	6
BP	GO:0070230	positive regulation of lymphocyte apoptotic process	6/2306	18/18670	0.01752	0.09632	0.0741	CCL5/IDO1/FNIP1/WNT5A/P2RX7/ADAM8	6
BP	GO:0070233	negative regulation of T cell apoptotic process	6/2306	18/18670	0.01752	0.09632	0.0741	CCL5/IL7R/IDO1/BMP4/FADD/ADA	6
BP	GO:0071318	cellular response to ATP	6/2306	18/18670	0.01752	0.09632	0.0741	PTGS2/P2RY11/SSH1/P2RX3/PDXP/P2RX7	6
BP	GO:0072079	nephron tubule formation	6/2306	18/18670	0.01752	0.09632	0.0741	SIX1/IRX3/SIX4/HES5/GATA3/OSR1	6
BP	GO:0090330	regulation of platelet aggregation	6/2306	18/18670	0.01752	0.09632	0.0741	C1QTNF1/PRKCA/PDPN/UBASH3B/ABAT/PRKCD	6
BP	GO:1903242	regulation of cardiac muscle hypertrophy in response to stress	6/2306	18/18670	0.01752	0.09632	0.0741	FOXO1/LMNA/ERRFI1/PPP3CA/MIR214/MIR199A2	6
BP	GO:1904262	negative regulation of TORC1 signaling	6/2306	18/18670	0.01752	0.09632	0.0741	SESN1/FNIP2/FNIP1/SESN3/SESN2/KPTN	6
BP	GO:0032506	cytokinetic process	10/2306	39/18670	0.01759	0.09632	0.0741	CHMP1B/ANXA11/CHMP4B/KLHDC8B/ARF1/BIN3/CHMP5/MITD1/MYH9/PDCD6IP	10
BP	GO:0045684	positive regulation of epidermis development	10/2306	39/18670	0.01759	0.09632	0.0741	BMP4/MSX2/CYP27B1/TGFB2/VDR/WNT5A/KRT2/TNF/FST/SULT2B1	10
BP	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	10/2306	39/18670	0.01759	0.09632	0.0741	ICAM1/TNFAIP3/CFLAR/FAS/FADD/TRAF2/BCL2L1/TNFRSF10B/ITPRIP/SERPINE1	10
BP	GO:0006541	glutamine metabolic process	7/2306	23/18670	0.01772	0.09632	0.0741	GFPT2/GLS/GLUD1/ASNS/ALDH5A1/PHGDH/CPS1	7
BP	GO:0009310	amine catabolic process	7/2306	23/18670	0.01772	0.09632	0.0741	KYNU/SAT1/IDO1/SMOX/HNMT/AADAT/ALDH7A1	7
BP	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules	7/2306	23/18670	0.01772	0.09632	0.0741	BMP2/CLDN1/CLDN12/CLDN14/CLDN20/CLDN7/CLDN17	7
BP	GO:0034123	positive regulation of toll-like receptor signaling pathway	7/2306	23/18670	0.01772	0.09632	0.0741	RSAD2/CYBA/FLOT1/WDFY1/TLR3/RTN4/PJA2	7
BP	GO:0050995	negative regulation of lipid catabolic process	7/2306	23/18670	0.01772	0.09632	0.0741	IL1B/ACACB/ADORA1/TNF/PDE3B/ADRA2A/CRTC3	7
BP	GO:0051152	positive regulation of smooth muscle cell differentiation	7/2306	23/18670	0.01772	0.09632	0.0741	SOD2/KIT/SMARCD3/SIRT1/MIR1-2/MIR125B1/ENG	7
BP	GO:0051589	negative regulation of neurotransmitter transport	7/2306	23/18670	0.01772	0.09632	0.0741	PNKD/ARL6IP5/RGS2/RGS4/SYT4/SLC30A1/ABAT	7
BP	GO:0072215	regulation of metanephros development	7/2306	23/18670	0.01772	0.09632	0.0741	LIF/BASP1/STAT1/BMP4/PDGFRB/WWTR1/YAP1	7
BP	GO:0089718	amino acid import across plasma membrane	7/2306	23/18670	0.01772	0.09632	0.0741	SLC7A2/SLC7A11/ARL6IP5/SLC3A2/RGS2/RGS4/CLN8	7
BP	GO:2000050	regulation of non-canonical Wnt signaling pathway	7/2306	23/18670	0.01772	0.09632	0.0741	DAB2/ANKRD6/CSNK1E/DAAM2/WNT5A/ABL1/PLEKHA4	7
BP	GO:0003205	cardiac chamber development	31/2306	171/18670	0.01786	0.09688	0.07454	ID2/CITED2/BMP4/FZD1/RXRA/SLIT2/BMPR2/SMARCD3/DHRS3/MSX2/FGFRL1/FZD2/TGFB2/HECTD1/GATA6/ROBO1/MEF2C/WNT5A/PTK7/MIR1-2/RBM15/PLXND1/FKBP1A/GATA3/ARID1A/PRDM1/MYH6/ENG/UBE4B/MYH10/TBX3	31
BP	GO:0006937	regulation of muscle contraction	31/2306	171/18670	0.01786	0.09688	0.07454	ZC3H12A/PTGS2/KIT/PLCE1/GSTO1/CALM1/PDE4D/CAMK2D/MYL5/OXTR/ADA/EDN1/DMPK/F2R/RGS2/ITGA2/HCN4/ADORA1/ABAT/CALM2/ATP2A2/MIR1-2/DOCK4/PDE4B/NPPA/NMUR2/PDE5A/SRI/CASQ1/KCNB2/ADRA2A	31
BP	GO:0008645	hexose transmembrane transport	22/2306	112/18670	0.0179	0.09704	0.07466	PID1/IL1B/SLC2A6/C3/SLC2A1/HK2/GIP/SORT1/IRS1/TRIB3/EDN1/ENPP1/SLC2A12/ADIPOR2/CLIP3/SESN2/TNF/APPL2/PTPN11/IGF1/SLC2A10/SIRT6	22
BP	GO:0046634	regulation of alpha-beta T cell activation	19/2306	93/18670	0.01798	0.09741	0.07494	NFKBIZ/ZC3H12A/CD83/RIPK2/SH3RF1/ADORA2A/IRF1/TNFRSF14/HLA-E/IL12A/MYB/IL4R/SOCS1/ADA/EBI3/GATA3/PRDM1/SASH3/CBFB	19
BP	GO:0031348	negative regulation of defense response	41/2306	239/18670	0.01802	0.09752	0.07503	ZC3H12A/TNFAIP3/TNFAIP6/NFKB1/ADORA2A/PARP14/TNFRSF1B/HLA-E/SOCS3/TSPAN6/HLA-F/IRAK3/ETS1/KLF4/ADAR/ITCH/ADA/DHX58/SIRPA/ADCY7/PSMA1/ABCD1/SIGLEC10/ADORA1/VPS35/MICB/HAVCR2/SLAMF8/APPL2/TRAFD1/CNR2/GATA3/PRKCD/HLA-G/DUSP10/PPARG/PYDC2/TRIM38/IGF1/MAPKBP1/CYP19A1	41
BP	GO:0045471	response to ethanol	24/2306	125/18670	0.01807	0.0977	0.07517	ICAM1/VCAM1/CLDN1/CCL7/BIRC2/FYN/CCND1/ACTC1/ADCY7/TP53INP1/RGS2/POLB/ITPR2/RGS4/TNC/EPS8/GSN/ABAT/BGLAP/SPARC/GATA3/GRIN3A/ACTR2/STAT3	24
BP	GO:0032102	negative regulation of response to external stimulus	59/2306	365/18670	0.01813	0.09793	0.07534	ZC3H12A/TNFAIP3/TNFAIP6/NFKB1/CCL2/SERPINB2/TRIB1/ADORA2A/FGF2/C1QTNF1/TNFRSF1B/SOCS3/PLAU/TSPAN6/SLIT2/ETS1/KLF4/BACE1/ITCH/THBS1/UBASH3B/ADA/EDN1/DHX58/SEMA4D/SIRPA/ADCY7/SNAI2/BBS2/DUSP3/PSMA1/ABCD1/SIGLEC10/ROBO1/PHLDB2/WNT5A/ADORA1/VPS35/MICB/ABAT/HAVCR2/SLAMF8/APPL2/CNR2/GATA3/PRKCD/GRIN3A/SERPINE1/DUSP10/PPARG/CDKN1A/PYDC2/TRIM38/SEMA4F/IGF1/DVL1/SERPINF2/MAPKBP1/CYP19A1	59
BP	GO:0016482	cytosolic transport	29/2306	158/18670	0.01832	0.0988	0.07601	DAB2/DENND5A/RAB9A/SYS1/EPS15/SORT1/STX6/WIPI1/RDX/GCC2/CLTC/DCTN1/RHOBTB3/VPS35/PREPL/HOOK3/KLHL20/RAB9B/WDR91/STX16/ACTR2/TBC1D10C/AKTIP/MYO1D/RNF126/ANKRD27/VPS26A/MAGEL2/SNX3	29
BP	GO:0060402	calcium ion transport into cytosol	29/2306	158/18670	0.01832	0.0988	0.07601	BDKRB1/CXCL10/FGF2/PLCE1/GSTO1/FYN/CALM1/PDE4D/CAMK2D/PKD2/CXCL11/CCL3/CYBA/UBASH3B/CXCL9/TRPC1/F2R/ITPR2/TPCN1/P2RX3/CALM2/MIR1-2/FKBP1A/DIAPH1/ABL1/MCOLN1/SRI/P2RX7/CASQ1	29
BP	GO:1901988	negative regulation of cell cycle phase transition	45/2306	267/18670	0.01843	0.09932	0.07641	PSME2/CCL2/PSMA6/CDK6/PSMB10/FHL1/PSMB8/PSMB7/PSME1/PLK2/PSMB9/RPA2/PKD2/CCND1/KLF4/PSMA3/PRMT1/ZFP36L2/MAD1L1/CDC14B/GJC2/CARM1/PSMA1/PSMB2/CDKN2C/MIR19B2/BTG2/PSMB3/MIR137/ARID3A/CNOT8/PSMA8/ZNF830/CDK2AP2/CTDSP2/ZFYVE19/CDKN1A/PSME4/TFDP1/PSMB5/PSMG2/TAOK1/UIMC1/FOXO4/PSMF1	45
BP	GO:0072175	epithelial tube formation	25/2306	132/18670	0.01888	0.1017	0.07821	SIX1/BMP4/FZD1/IRX3/SHROOM3/STK4/FZD2/PODXL/TGFB2/CEP290/SIX4/WNT5A/HES5/PTK7/GATA3/ARID1A/SDC4/ABL1/BCL10/RALA/FGF10/MIB1/DVL1/OSR1/DVL2	25
BP	GO:0014855	striated muscle cell proliferation	17/2306	81/18670	0.01897	0.102	0.0785	FGF2/MEIS1/JARID2/SIX1/CFLAR/SIX5/RXRA/PIM1/TGFB2/GATA6/YAP1/MEF2C/AKIRIN1/MIR19B2/MIR1-2/MIR199A2/STAT3	17
BP	GO:0016358	dendrite development	40/2306	233/18670	0.01907	0.1025	0.07884	SLC11A2/NTN1/SIPA1L1/DBN1/CAPRIN1/EEF2K/PLK2/FYN/NEUROG3/KIDINS220/SEMA4D/SDC2/MAP1A/LPAR1/HECW2/CARM1/MEF2C/ITPKA/CDK5/ARF6/BHLHB9/ARF1/PDLIM5/YWHAH/DLG4/TMEM106B/ASAP1/PPP3CA/GRIN3A/TRAPPC4/VAMP7/ACTR2/FARP1/CDC42/DVL1/NEDD4/NGEF/ANKRD27/CRKL/PICALM	40
BP	GO:0150063	visual system development	59/2306	366/18670	0.01909	0.1025	0.07884	NINJ1/NDP/AHI1/MEIS1/C3/SLC7A11/ALDH1A3/VEGFA/BMP4/PDGFRB/SIX5/IRX5/RDH10/BCAR3/RXRA/RHOJ/BMPR2/KLF4/SMARCD3/CRYAB/CRYGS/RAB3GAP1/MYOM1/COL5A2/HIPK2/TGFB2/MITF/WNT5B/ZDHHC16/LRP5/CEP290/IMPDH2/WNT5A/SHROOM2/HES5/FJX1/CDKN1C/RAB18/FBN1/SH3PXD2B/TOPORS/CLN8/SALL2/FZD4/OSR2/PTPRM/ATP8A2/GATA3/COL4A1/ARID1A/PRDM1/MAX/RDH13/FGF10/MYH10/STAT3/COL5A1/MAB21L2/NPHP1	59
BP	GO:0030217	T cell differentiation	41/2306	240/18670	0.01922	0.1031	0.07931	NFKBIZ/ZC3H12A/IL6/RELB/CD83/RIPK2/SH3RF1/CDK6/IRF1/TNFSF9/KIT/PIK3CD/IL7R/MAFB/RSAD2/PRR7/BMP4/IL12A/IL18R1/MYB/IL4R/SOCS1/FADD/IL15/CYLD/ADA/ZFP36L2/RPL22/STAT6/BCL3/FZD8/GATA3/HLA-G/PRDM1/ABL1/DUSP10/STAT3/SASH3/FZD7/ADAM8/CBFB	41
BP	GO:0030324	lung development	31/2306	172/18670	0.01928	0.1031	0.07936	LIF/HSD11B1/PDPN/EPAS1/SLC7A11/VEGFA/BMP4/KLF2/PDGFRB/LIPA/RDH10/BMPR2/ADA/SPRY1/GATA6/CYP1A2/ERRFI1/THRA/YAP1/CRISPLD2/WNT5A/RCN3/RAB3A/TNC/PTK7/TNF/SPARC/RSPO2/CEBPA/FGF10/NFIB	31
BP	GO:0000187	activation of MAPK activity	28/2306	152/18670	0.01929	0.1031	0.07936	BMP2/IRAK2/IL1B/RIPK2/ITGA1/ERN1/KIT/FGF2/DAXX/PLCE1/DUSP6/THBS1/TGFA/GHR/LPAR1/WNT5A/GDF15/TNF/MAP3K2/MLKL/UBB/PTPN11/FGF10/DUSP5/IGF1/P2RX7/TAOK1/CRKL	28
BP	GO:0019369	arachidonic acid metabolic process	12/2306	51/18670	0.01935	0.1031	0.07936	PTGS2/PTGES/PLA2G4A/PLA2G4C/CYP2U1/CYP1A2/DAGLA/DAGLB/PTGS1/FAAH2/CYP2C19/CYP2S1	12
BP	GO:0006073	cellular glucan metabolic process	16/2306	75/18670	0.01935	0.1031	0.07936	PYGL/IL6ST/PPP1R3F/UGP2/CALM1/IRS1/PGM2L1/DYRK2/PHLDA2/ENPP1/PHKB/GYG1/GYS2/PHKA2/IGF1/GNMT	16
BP	GO:0044042	glucan metabolic process	16/2306	75/18670	0.01935	0.1031	0.07936	PYGL/IL6ST/PPP1R3F/UGP2/CALM1/IRS1/PGM2L1/DYRK2/PHLDA2/ENPP1/PHKB/GYG1/GYS2/PHKA2/IGF1/GNMT	16
BP	GO:0032892	positive regulation of organic acid transport	9/2306	34/18670	0.01938	0.1031	0.07936	IL1B/ADORA2A/FABP3/EDN1/RAB3GAP1/SYT4/ABAT/STXBP1/P2RX7	9
BP	GO:0070884	regulation of calcineurin-NFAT signaling cascade	9/2306	34/18670	0.01938	0.1031	0.07936	FHL2/DYRK2/LMCD1/RCAN1/TNF/RCAN2/IGF1/HOMER2/CHP2	9
BP	GO:0106056	regulation of calcineurin-mediated signaling	9/2306	34/18670	0.01938	0.1031	0.07936	FHL2/DYRK2/LMCD1/RCAN1/TNF/RCAN2/IGF1/HOMER2/CHP2	9
BP	GO:1904030	negative regulation of cyclin-dependent protein kinase activity	9/2306	34/18670	0.01938	0.1031	0.07936	TNFAIP3/NR2F2/LATS2/KAT2B/HEXIM2/CDKN2C/CDKN1C/CEBPA/CDKN1A	9
BP	GO:0050769	positive regulation of neurogenesis	74/2306	474/18670	0.01957	0.1041	0.08007	BMP2/IL6/IL1B/LIF/ID2/CSF1/GDPD5/KIT/NTN1/ZFYVE27/TNFRSF1B/DBN1/CAPRIN1/IL6ST/VEGFA/EEF2K/CFLAR/BMP4/PAK1/MYB/FZD1/TCF12/FYN/SLIT2/IRX3/BMPR2/CCL3/RUFY3/NEUROG3/BEND6/SMARCD3/KIDINS220/DPYSL3/SEMA4D/GJC2/RGS2/LPAR1/CLCF1/CSNK1E/GDF5/ROBO1/MEF2C/ITPKA/ATF1/WNT5A/BHLHB9/SYT4/ARF1/MIR137/PTK7/TNF/HOXD3/MIR125B1/NUMBL/FZD4/DLG4/ATP8A2/PLXND1/SOCS2/TMEM106B/GDI1/SYT1/NPTN/VAMP7/PPARG/ACTR2/GDF6/CDH4/ITGA6/DVL1/DVL2/ANKRD27/CRKL/SNX3	74
BP	GO:0042698	ovulation cycle	15/2306	69/18670	0.01962	0.1041	0.0801	EREG/AFP/SLIT2/ETS1/OXTR/TGFB2/HAS2/AXL/SIRT1/TIMP4/HAS1/FZD4/PTX3/ZNF830/NCOR2	15
BP	GO:0043574	peroxisomal transport	15/2306	69/18670	0.01962	0.1041	0.0801	ACOX2/IDH1/NUDT7/CROT/AMACR/ABCD1/DECR2/LONP2/PEX1/ACOT8/PECR/UBB/SCP2/PEX26/USP9X	15
BP	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	26/2306	139/18670	0.01963	0.1041	0.0801	CXCL10/ADORA2A/ABCA1/PRKCA/PTGFR/PDE4D/CXCL11/PTGER2/PTHLH/CXCL9/ADM2/MC1R/ADCY7/GNA13/ADCY9/ADCY3/ARRDC3/RAMP1/MRAP2/GPR161/MIR1-2/IAPP/ADRB3/LGR4/ADRA2A/GNG2	26
BP	GO:0051099	positive regulation of binding	32/2306	179/18670	0.0197	0.1044	0.08032	BMP2/RIPK2/PLK2/BMP4/KLF4/EDF1/STK4/TRIB3/TCF7L2/HIPK2/ERCC2/ITGA2/MMP9/FLOT1/PARP9/MEF2C/CDK5/WNT5A/TRAF2/ARF6/CRBN/TXN/EIF3E/PLXND1/FKBP1A/TRIM6/GATA3/ABL1/PPARG/TICAM1/IGF1/AKTIP	32
BP	GO:0048640	negative regulation of developmental growth	22/2306	113/18670	0.01971	0.1044	0.08032	NTN1/MEIS1/JARID2/BMP4/PAK1/WWC1/STK4/SEMA4D/RGS2/BBS2/IFRD1/CDK5/WNT5A/RGS4/GDF15/MIR1-2/SOCS2/RTN4/DUSP10/CDKN1A/SEMA4F/MIR199A2	22
BP	GO:0045667	regulation of osteoblast differentiation	24/2306	126/18670	0.01979	0.1047	0.08055	BMP2/IL6/ID2/CDK6/CEBPD/CEBPB/IFITM1/IL6ST/BMP4/BMPR2/MSX2/SEMA4D/TMEM64/SNAI2/LRP5/MEF2C/TP63/RANBP3L/DDX5/TNF/CEBPA/ID3/IGF1/ZHX3	24
BP	GO:0051289	protein homotetramerization	19/2306	94/18670	0.02001	0.1058	0.08139	SOD2/GLS/ALDH1A3/HINT3/ACACB/GBP5/RXRA/PKD2/CRYZ/ACACA/CBR4/IMPDH2/TP63/APPL2/CD79A/ALDH5A1/MCOLN1/GNMT/CRTC3	19
BP	GO:0040013	negative regulation of locomotion	63/2306	396/18670	0.02056	0.1086	0.08355	IL33/CCL2/TRIB1/ADORA2A/PPARGC1A/CITED2/RECK/FGF2/IFITM1/MCC/CORO1C/RNF20/VCL/TRIM25/SLIT2/NR2F2/KLF4/THBS1/ADA/KRT16/DPYSL3/CARD10/SEMA4D/RHOB/TP53INP1/NISCH/MITF/STARD13/CYGB/DUSP3/MEOX2/ROBO1/MEF2C/PHLDB2/MIR19B2/WNT5A/ARRDC3/ADORA1/TRIM21/SULF1/RGN/PFN2/MIR137/MIR491/SLAMF8/TACSTD2/HAS1/PTPRM/SP100/GATA3/ADARB1/SERPINE1/MIR214/DUSP10/ARHGDIB/PPARG/EPHA1/ENG/SEMA4F/MIR218-1/STAT3/CYP19A1/ADORA3	63
BP	GO:0043506	regulation of JUN kinase activity	18/2306	88/18670	0.02066	0.1087	0.08361	RIPK2/ERN1/DAXX/DNAJA1/PAK1/EDN1/FZD8/WNT5A/TRAF2/ARHGEF5/TNF/MAP3K2/MLKL/FZD4/DUSP10/DVL2/TAOK1/ZNF675	18
BP	GO:0048644	muscle organ morphogenesis	18/2306	88/18670	0.02066	0.1087	0.08361	BMP2/LIF/ARID5B/FZD1/RXRA/ACTC1/MYOM1/FZD2/TGFB2/WNT5A/MYOM3/MYLK/FKBP1A/ADARB1/MYH6/ENG/UBE4B/SIRT6	18
BP	GO:1900407	regulation of cellular response to oxidative stress	18/2306	88/18670	0.02066	0.1087	0.08361	SOD2/GPR37L1/HSPB1/MMP3/NCOA7/SLC7A11/FZD1/LANCL1/FYN/GCH1/NME5/ABCD1/SIRT1/ATG7/RGN/TXN/TNF/OXR1	18
BP	GO:1903557	positive regulation of tumor necrosis factor superfamily cytokine production	18/2306	88/18670	0.02066	0.1087	0.08361	RIPK2/HSPB1/IFIH1/IFNGR1/HLA-E/DDX58/CCL3/FADD/CYBA/THBS1/AKAP12/WNT5A/HAVCR2/TLR3/PTPN11/TICAM1/SASH3/ADAM8	18
BP	GO:1903725	regulation of phospholipid metabolic process	18/2306	88/18670	0.02066	0.1087	0.08361	KIT/FGF2/PDGFRB/SOCS1/SOCS3/RAB38/FABP3/IRS1/KLF4/IDH1/PIK3R2/PIK3R3/TNFAIP8L3/ARF1/SOCS2/PRKCD/WDR91/CAPN2	18
BP	GO:0003015	heart process	48/2306	290/18670	0.02083	0.1092	0.08402	ZC3H12A/GPD1L/EPAS1/POPDC2/WWTR1/GSTO1/IRX5/FYN/CALM1/PDE4D/CAMK2D/HSPB7/GCH1/ADA/ACTC1/EDN1/DMPK/HBEGF/TRPC1/SGCD/TGFB2/RGS2/THRA/YAP1/HCN4/ITPR2/RGS4/ADORA1/PPCS/KCND1/CACNA1F/CACNA1B/SGCG/CALM2/ATP2A2/MIR1-2/STIM1/SNTA1/NPR2/PDE4B/KCND3/ATP1A4/MYH6/NPPA/PDE5A/SRI/CASQ1/ADORA3	48
BP	GO:0002369	T cell cytokine production	10/2306	40/18670	0.02093	0.1092	0.08402	IL6/IL1B/RSAD2/TNFRSF1B/IL12A/IL18R1/HLA-F/TRAF2/GATA3/SASH3	10
BP	GO:0009187	cyclic nucleotide metabolic process	10/2306	40/18670	0.02093	0.1092	0.08402	PDE4D/PDE1A/PTHLH/ADCY7/ADCY9/ADCY3/NPR2/PDE4B/NPPA/PDE5A	10
BP	GO:0045124	regulation of bone resorption	10/2306	40/18670	0.02093	0.1092	0.08402	TNFAIP3/IL6/PRKCA/UBASH3B/TMEM64/BGLAP/IAPP/TNFRSF11B/P2RX7/ADAM8	10
BP	GO:0045823	positive regulation of heart contraction	10/2306	40/18670	0.02093	0.1092	0.08402	PDE4D/GCH1/ADA/EDN1/TGFB2/RGS2/RGS4/ATP2A2/MIR1-2/NPPA	10
BP	GO:0006294	nucleotide-excision repair, preincision complex assembly	8/2306	29/18670	0.02106	0.1092	0.08402	RAD23B/RPA2/ERCC2/DDB2/GTF2H5/UBB/MNAT1/CDK7	8
BP	GO:0007263	nitric oxide mediated signal transduction	8/2306	29/18670	0.02106	0.1092	0.08402	MT2A/DDAH1/VEGFA/RASD1/THBS1/DDAH2/SPINK1/PDE5A	8
BP	GO:0010575	positive regulation of vascular endothelial growth factor production	8/2306	29/18670	0.02106	0.1092	0.08402	PTGS2/IL6/IL1B/IL1A/C3/IL6ST/SULF2/SULF1	8
BP	GO:0010954	positive regulation of protein processing	8/2306	29/18670	0.02106	0.1092	0.08402	IL1B/BAG2/C3/NKD2/TNP2/GSN/MYH9/ADAM8	8
BP	GO:0035666	TRIF-dependent toll-like receptor signaling pathway	8/2306	29/18670	0.02106	0.1092	0.08402	BIRC3/BIRC2/IRF7/TRAF3/FADD/TLR3/UBB/TICAM1	8
BP	GO:0044068	modulation by symbiont of host cellular process	8/2306	29/18670	0.02106	0.1092	0.08402	ZC3H12A/TNIP1/CCL8/EIF2AK4/KPNA3/ATG7/BCL2L1/KPNA2	8
BP	GO:0060142	regulation of syncytium formation by plasma membrane fusion	8/2306	29/18670	0.02106	0.1092	0.08402	CXCL10/CFLAR/IL4R/CXCL9/FLOT1/EHD1/GDF15/CAPN2	8
BP	GO:0060441	epithelial tube branching involved in lung morphogenesis	8/2306	29/18670	0.02106	0.1092	0.08402	BMP4/RDH10/SPRY1/YAP1/TNC/TNF/RSPO2/FGF10	8
BP	GO:0070102	interleukin-6-mediated signaling pathway	8/2306	29/18670	0.02106	0.1092	0.08402	IL6/STAT1/IL6ST/SOCS3/MIR125B1/CEBPA/PTPN11/STAT3	8
BP	GO:0070229	negative regulation of lymphocyte apoptotic process	8/2306	29/18670	0.02106	0.1092	0.08402	CCL5/IL7R/IDO1/BMP4/FADD/SLC39A10/ADA/BCL10	8
BP	GO:0070528	protein kinase C signaling	8/2306	29/18670	0.02106	0.1092	0.08402	GPD1L/VEGFA/CD40/MYADM/AKAP12/MC1R/FLOT1/WNT5A	8
BP	GO:0090162	establishment of epithelial cell polarity	8/2306	29/18670	0.02106	0.1092	0.08402	CYTH3/WNT5A/MYO18A/ARF6/HES5/PTK7/CDC42/FERMT1	8
BP	GO:0097581	lamellipodium organization	17/2306	82/18670	0.02126	0.1101	0.08475	FSCN1/KIT/PDPN/CORO1C/AUTS2/VCL/CD44/SLIT2/CCDC88A/PLEKHO1/AKIRIN1/ARPC2/BIN3/MIR214/CDC42/SH2B1/WASF2	17
BP	GO:0002027	regulation of heart rate	20/2306	101/18670	0.02138	0.1107	0.08516	GPD1L/EPAS1/POPDC2/IRX5/CALM1/PDE4D/CAMK2D/GCH1/ADA/EDN1/HCN4/RGS4/CALM2/ATP2A2/MIR1-2/SNTA1/KCND3/MYH6/NPPA/SRI	20
BP	GO:0002688	regulation of leukocyte chemotaxis	22/2306	114/18670	0.02167	0.1119	0.08607	CCL5/IL6/CXCL10/CCL2/CSF1/CCL7/VEGFA/JAM3/IL12A/CMKLR1/SLIT2/CCL3/THBS1/EDN1/CCL1/AKIRIN1/WNT5A/PGF/SLAMF8/SERPINE1/GAS6/CYP19A1	22
BP	GO:0015749	monosaccharide transmembrane transport	22/2306	114/18670	0.02167	0.1119	0.08607	PID1/IL1B/SLC2A6/C3/SLC2A1/HK2/GIP/SORT1/IRS1/TRIB3/EDN1/ENPP1/SLC2A12/ADIPOR2/CLIP3/SESN2/TNF/APPL2/PTPN11/IGF1/SLC2A10/SIRT6	22
BP	GO:0030282	bone mineralization	22/2306	114/18670	0.02167	0.1119	0.08607	BMP2/PTGS2/ISG15/BMP4/BMPR2/CCL3/CYP27B1/PTHLH/ENPP1/ERCC2/MEF2C/SRGN/BGLAP/BMP2K/OSR2/RSPO2/LGR4/COL1A2/IGF1/OSR1/P2RX7/SNX10	22
BP	GO:0099504	synaptic vesicle cycle	34/2306	194/18670	0.02189	0.1123	0.08641	PPP3CC/PLD1/ADORA2A/ROCK1/VAMP4/STX3/BACE1/STX6/RAB3GAP1/CDK5/SNAP47/RAB3A/ARF6/SYT4/PREPL/PFN2/DGKI/ACTB/BRSK2/ATP2A2/STXBP5/SNPH/STXBP1/SYT1/GRIN3A/TOR1A/NAPB/DVL1/ACTG1/P2RX7/PCDH17/PPFIA3/GRIPAP1/PICALM	34
BP	GO:1902115	regulation of organelle assembly	34/2306	194/18670	0.02189	0.1123	0.08641	CSF2/FSCN1/CHMP1B/PLK2/CHMP4B/TRIM37/CCDC88A/CYLD/DYNC2LI1/EDN1/RDX/RAB3GAP1/GPSM2/SDCBP/KAT2B/TCHP/MEF2C/RNF5/EVI5L/ARHGEF5/GSN/RNF4/TNF/DYNLL1/MIR1-2/ASAP1/LRFN4/CHMP5/SDC4/MARK4/PIP4K2A/MNS1/FEZ2/PDCD6IP	34
BP	GO:0014075	response to amine	11/2306	46/18670	0.0219	0.1123	0.08641	ICAM1/ADORA2A/OXTR/HNMT/RGS2/ITGA2/RGS4/ASS1/CNR2/CPS1/PPP3CA	11
BP	GO:0060443	mammary gland morphogenesis	11/2306	46/18670	0.0219	0.1123	0.08641	CSF1/NTN1/BMP4/MSX2/STAT6/LRP5/VDR/WNT5A/ELF3/FGF10/TBX3	11
BP	GO:0097720	calcineurin-mediated signaling	11/2306	46/18670	0.0219	0.1123	0.08641	PPP3CC/FHL2/DYRK2/LMCD1/RCAN1/TNF/PPP3CA/RCAN2/IGF1/HOMER2/CHP2	11
BP	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	5/2306	14/18670	0.02192	0.1123	0.08641	ZNHIT3/RPL7/BOP1/URB1/FTSJ3	5
BP	GO:0042487	regulation of odontogenesis of dentin-containing tooth	5/2306	14/18670	0.02192	0.1123	0.08641	BMP2/CSF1/BMP4/RSPO2/TNFRSF11B	5
BP	GO:0072498	embryonic skeletal joint development	5/2306	14/18670	0.02192	0.1123	0.08641	BMP4/HOXA11/OSR2/EXT1/OSR1	5
BP	GO:1905205	positive regulation of connective tissue replacement	5/2306	14/18670	0.02192	0.1123	0.08641	ROCK1/PPP3CA/ROCK2/MIR214/MIR199A2	5
BP	GO:0042102	positive regulation of T cell proliferation	19/2306	95/18670	0.02221	0.1134	0.08728	CCL5/IL6/CD70/VCAM1/IL1B/RIPK2/TNFSF9/PDCD1LG2/IL6ST/TNFSF13B/HLA-E/IL12A/FADD/IL15/EBI3/EFNB1/HAVCR2/IGF1/SASH3	19
BP	GO:0042116	macrophage activation	19/2306	95/18670	0.02221	0.1134	0.08728	ZC3H12A/NAMPT/IL6/CSF2/SLC7A2/IL33/IFNGR1/IL4R/CCL3/THBS1/WNT5A/MYO18A/HAVCR2/TNF/TLR3/CEBPA/PJA2/TICAM1/CRTC3	19
BP	GO:0044070	regulation of anion transport	19/2306	95/18670	0.02221	0.1134	0.08728	IL1B/ADORA2A/CEBPB/FABP3/ARL6IP5/THBS1/EDN1/RAB3GAP1/RGS2/RGS4/ADORA1/SYT4/ABAT/ATP8A2/STXBP1/PRKCD/ROS1/OSR1/P2RX7	19
BP	GO:0050766	positive regulation of phagocytosis	15/2306	70/18670	0.02221	0.1134	0.08728	IL1B/CCL2/C3/IL15RA/CYBA/IL15/SIRPA/ITGA2/MYO18A/TNF/APPL2/PTX3/GAS6/PPARG/RAB31	15
BP	GO:0001654	eye development	58/2306	362/18670	0.02235	0.114	0.08773	NINJ1/NDP/AHI1/MEIS1/SLC7A11/ALDH1A3/VEGFA/BMP4/PDGFRB/SIX5/IRX5/RDH10/BCAR3/RXRA/RHOJ/BMPR2/KLF4/SMARCD3/CRYAB/CRYGS/RAB3GAP1/MYOM1/COL5A2/HIPK2/TGFB2/MITF/WNT5B/ZDHHC16/LRP5/CEP290/IMPDH2/WNT5A/SHROOM2/HES5/FJX1/CDKN1C/RAB18/FBN1/SH3PXD2B/TOPORS/CLN8/SALL2/FZD4/OSR2/PTPRM/ATP8A2/GATA3/COL4A1/ARID1A/PRDM1/MAX/RDH13/FGF10/MYH10/STAT3/COL5A1/MAB21L2/NPHP1	58
BP	GO:0046488	phosphatidylinositol metabolic process	31/2306	174/18670	0.02241	0.114	0.08773	FGF2/PIK3CD/PLA2G4A/PDGFRB/SOCS1/SOCS3/PLA2G4C/PIGV/PIK3R2/PTPN13/PIK3R3/IMPA2/RAB4A/PLEKHA3/EFR3A/PLA2G12A/ARF1/ARF3/SOCS2/MPPE1/INPP5B/PIGK/PIGS/IP6K3/PIP4K2A/INPP1/PI4K2B/SH3YL1/SBF1/PLEKHA4/LCLAT1	31
BP	GO:0003179	heart valve morphogenesis	12/2306	52/18670	0.02241	0.114	0.08773	BMP2/ROCK1/BMP4/SLIT2/BMPR2/FGFRL1/TGFB2/SNAI2/ROBO1/MEF2C/GATA3/ROCK2	12
BP	GO:0050996	positive regulation of lipid catabolic process	7/2306	24/18670	0.02242	0.114	0.08773	IL1B/IRS1/CPT1A/ABCD1/ADORA1/ABHD5/PRKCD	7
BP	GO:0032355	response to estradiol	25/2306	134/18670	0.02246	0.114	0.08773	PTGS2/PPARGC1A/ARNT2/CFLAR/PDGFRB/PTGFR/COL1A1/BCL2L2/ETS1/NR2F2/CCND1/MSX2/OXTR/SRD5A1/CRYAB/ITGA2/CYP1A2/GJB2/ASS1/STXBP1/SOCS2/NCOR2/MBD4/FGF10/STAT3	25
BP	GO:0006826	iron ion transport	14/2306	64/18670	0.02249	0.114	0.08773	SLC39A14/SLC11A2/SLC25A28/ATP6V1E2/ATP6V0B/FTH1/SLC25A37/ATP6V0E2/CLTC/ARHGAP1/FTHL17/MCOLN1/STEAP2/ATP6V1E1	14
BP	GO:0032768	regulation of monooxygenase activity	14/2306	64/18670	0.02249	0.114	0.08773	IL1B/NFKB1/NPR3/DDAH1/CALM1/GCH1/GLA/CYP27B1/NOSTRIN/CYGB/VDR/TNF/CNR2/DDAH2	14
BP	GO:0045670	regulation of osteoclast differentiation	14/2306	64/18670	0.02249	0.114	0.08773	CSF1/CEBPB/MAFB/CCL3/UBASH3B/MITF/TMEM64/FBN1/TNF/BGLAP/TFE3/TLR3/PIAS3/ZNF675	14
BP	GO:2000378	negative regulation of reactive oxygen species metabolic process	14/2306	64/18670	0.02249	0.114	0.08773	ZC3H12A/MMP3/HK2/CFLAR/FYN/GLA/CRYAB/SIRPA/ABCD1/RGN/ROCK2/VDAC1/MIR199A2/STAT3	14
BP	GO:0030520	intracellular estrogen receptor signaling pathway	13/2306	58/18670	0.02258	0.1141	0.08778	PAK1/LBH/YAP1/CARM1/TP63/DDX5/KCTD6/GPAM/ARID1A/UFSP2/TADA3/NCOA6/CBFB	13
BP	GO:0031663	lipopolysaccharide-mediated signaling pathway	13/2306	58/18670	0.02258	0.1141	0.08778	NFKBIA/TNFAIP3/IRAK2/CCL5/IL1B/RIPK2/CCL2/TRIB1/PRKCA/CCL3/TNF/BCL10/TICAM1	13
BP	GO:0035904	aorta development	13/2306	58/18670	0.02258	0.1141	0.08778	SIX1/PDGFRB/PKD2/TGFB2/HECTD1/ROBO1/NKX3-1/LOXL1/MYLK/PLXND1/PRDM1/ENG/MYH10	13
BP	GO:0060997	dendritic spine morphogenesis	13/2306	58/18670	0.02258	0.1141	0.08778	SIPA1L1/DBN1/CAPRIN1/EEF2K/ITPKA/CDK5/BHLHB9/PDLIM5/DLG4/ACTR2/CDC42/DVL1/NGEF	13
BP	GO:0010770	positive regulation of cell morphogenesis involved in differentiation	28/2306	154/18670	0.02264	0.1142	0.08789	NTN1/ZFYVE27/DBN1/CAPRIN1/VEGFA/EEF2K/PAK1/NEDD9/SLIT2/BMPR2/MYADM/LIMS2/RUFY3/SEMA4D/HAS2/ROBO1/ITPKA/ARPC2/BHLHB9/PLXND1/GDI1/ABL1/VAMP7/ACTR2/CDC42/CDH4/ANKRD27/CRKL	28
BP	GO:0061025	membrane fusion	28/2306	154/18670	0.02264	0.1142	0.08789	TAP1/TAP2/MX1/MX2/SAMD9L/NKD2/BET1/VAMP4/STX3/STX6/TBC1D4/PPIA/NOX5/ATG7/SNAP47/RAB3A/SYT4/TMEM175/SAMD9/STXBP1/SYT1/STX16/GAS6/VAMP7/TAPBP/TSNARE1/GCA/ANKRD27	28
BP	GO:0030968	endoplasmic reticulum unfolded protein response	23/2306	121/18670	0.02268	0.1143	0.08798	CCL2/ERN1/PPP1R15A/TBL2/FICD/HERPUD1/DNAJB9/CCND1/LMNA/HDGF/WIPI1/DCTN1/SERP2/DNAJC3/HYOU1/ASNS/SSR1/CTDSP2/RNF121/TSPYL2/TLN1/TMEM33/BFAR	23
BP	GO:0030336	negative regulation of cell migration	54/2306	334/18670	0.02285	0.1147	0.08828	IL33/CCL2/TRIB1/PPARGC1A/CITED2/RECK/FGF2/IFITM1/MCC/CORO1C/RNF20/VCL/SLIT2/NR2F2/KLF4/THBS1/ADA/KRT16/DPYSL3/CARD10/RHOB/TP53INP1/NISCH/MITF/STARD13/CYGB/DUSP3/MEOX2/ROBO1/MEF2C/PHLDB2/MIR19B2/ADORA1/SULF1/PFN2/MIR137/MIR491/SLAMF8/TACSTD2/HAS1/PTPRM/SP100/ADARB1/SERPINE1/MIR214/DUSP10/ARHGDIB/PPARG/EPHA1/ENG/MIR218-1/STAT3/CYP19A1/ADORA3	54
BP	GO:0010506	regulation of autophagy	53/2306	327/18670	0.02296	0.1147	0.08828	ZC3H12A/NAMPT/RIPK2/ERN1/HSPB1/DRAM1/FBXL2/FOXO1/DAPK1/SESN1/TP53INP2/HK2/ROCK1/PLK2/ATP6V1E2/PLEKHF1/ATP6V0B/PIM2/CHMP4B/NRBP2/ATP6V0E2/PIK3R2/TRIB3/EIF2AK4/RAB3GAP1/SH3BP4/TP53INP1/SESN3/RNF5/CDK5/SIRT1/OPTN/ATG7/VPS35/TRIM21/TPCN1/CAMKK2/SESN2/PAFAH1B2/PRKAB2/ABL1/VDAC1/POLDIP2/PIP4K2A/FEZ2/TICAM1/ATP13A2/MIR199A2/STAT3/NEDD4/ATP6V1E1/VPS26A/OSBPL7	53
BP	GO:0003085	negative regulation of systemic arterial blood pressure	6/2306	19/18670	0.02299	0.1147	0.08828	SOD2/GPR37L1/BMPR2/ADORA1/ADRB3/NPPA	6
BP	GO:0010888	negative regulation of lipid storage	6/2306	19/18670	0.02299	0.1147	0.08828	NFKBIA/IL6/ABCA1/TNF/ABHD5/PPARG	6
BP	GO:0019184	nonribosomal peptide biosynthetic process	6/2306	19/18670	0.02299	0.1147	0.08828	SLC7A11/CHAC2/HAGH/BDH2/CNDP2/MGST2	6
BP	GO:0034755	iron ion transmembrane transport	6/2306	19/18670	0.02299	0.1147	0.08828	SLC39A14/SLC11A2/SLC25A28/SLC25A37/MCOLN1/STEAP2	6
BP	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process	6/2306	19/18670	0.02299	0.1147	0.08828	ELOVL5/ELOVL7/ACSL5/ELOVL2/HSD17B12/ELOVL3	6
BP	GO:0060231	mesenchymal to epithelial transition	6/2306	19/18670	0.02299	0.1147	0.08828	LIF/BASP1/STAT1/BMP4/GATA3/FZD7	6
BP	GO:0060973	cell migration involved in heart development	6/2306	19/18670	0.02299	0.1147	0.08828	BMP4/PDGFRB/SNAI2/FLRT3/MIR1-2/ENG	6
BP	GO:0071731	response to nitric oxide	6/2306	19/18670	0.02299	0.1147	0.08828	MMP3/FOXO1/CFLAR/EGLN1/TRAF2/MTR	6
BP	GO:1901741	positive regulation of myoblast fusion	6/2306	19/18670	0.02299	0.1147	0.08828	IL4R/CXCL9/FLOT1/EHD1/GDF15/CAPN2	6
BP	GO:0051271	negative regulation of cellular component movement	61/2306	384/18670	0.023	0.1147	0.08828	IL33/CCL2/TRIB1/PPARGC1A/CITED2/RECK/FGF2/IFITM1/MCC/CORO1C/RNF20/VCL/SLIT2/NR2F2/KLF4/THBS1/ADA/KRT16/DPYSL3/CARD10/SEMA4D/RHOB/TP53INP1/NISCH/MITF/STARD13/CYGB/DUSP3/MEOX2/ROBO1/MEF2C/PHLDB2/MIR19B2/WNT5A/ADORA1/SULF1/RGN/PFN2/MIR137/MIR491/SLAMF8/TACSTD2/ACTN4/HAS1/PTPRM/SP100/GATA3/ADARB1/SERPINE1/MIR214/DUSP10/ARHGDIB/PPARG/EPHA1/ENG/CNIH2/SEMA4F/MIR218-1/STAT3/CYP19A1/ADORA3	61
BP	GO:1901019	regulation of calcium ion transmembrane transporter activity	18/2306	89/18670	0.023	0.1147	0.08828	GSTO1/RRAD/CALM1/PDE4D/CAMK2D/PKD2/THADA/GEM/STAC/RGN/CALM2/STIM1/FKBP1A/PDE4B/NPPA/SRI/CASQ1/ADRA2A	18
BP	GO:0009266	response to temperature stimulus	41/2306	243/18670	0.02319	0.1156	0.08893	NFKBIA/PTGS2/CXCL10/IL1A/BAG2/PPARGC1A/ST8SIA1/DAXX/FOXO1/MYOF/DNAJA1/RPA2/CAMK2D/NUP133/NFE2L1/THBS1/EIF2AK4/CRYAB/TP53INP1/DNAJC3/THRA/TMEM135/LRP11/STAC/SIRT1/ABCC2/ADORA1/MICB/P2RX3/CAMK2G/APPL2/ATP2A2/EIF2B5/EIF2B4/GLRX2/MMP24/PPARG/CDKN1A/NUP35/IGF1/CASQ1	41
BP	GO:0060338	regulation of type I interferon-mediated signaling pathway	9/2306	35/18670	0.02331	0.116	0.08922	IFNAR2/IRF7/ADAR/FADD/WNT5A/TRIM6/USP18/PTPN11/ZBP1	9
BP	GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway	9/2306	35/18670	0.02331	0.116	0.08922	NFKBIA/BIRC3/TNFAIP3/IRAK2/RIPK2/BIRC2/ITCH/CYLD/UBB	9
BP	GO:0010595	positive regulation of endothelial cell migration	24/2306	128/18670	0.0236	0.1174	0.09029	ZC3H12A/PTGS2/HSPB1/FGF2/PRKCA/VEGFA/PLK2/BMP4/CD40/RHOJ/ETS1/BMPR2/THBS1/EDN1/RHOB/AMOTL1/SIRT1/WNT5A/SPARC/GATA3/ABL1/ROCK2/MIR199A2/ATOH8	24
BP	GO:0008652	cellular amino acid biosynthetic process	17/2306	83/18670	0.02376	0.1177	0.09056	GLS/MTHFD2L/PSPH/GLUD1/SEPHS1/PSAT1/PLOD2/GAMT/MTR/ABAT/ASS1/BHMT2/ASNS/PHGDH/MTAP/CPS1/BCAT2	17
BP	GO:0045582	positive regulation of T cell differentiation	17/2306	83/18670	0.02376	0.1177	0.09056	NFKBIZ/CD83/RIPK2/TNFSF9/IL7R/IL12A/MYB/IL4R/SOCS1/CYLD/ADA/GATA3/HLA-G/DUSP10/SASH3/ADAM8/CBFB	17
BP	GO:0048145	regulation of fibroblast proliferation	17/2306	83/18670	0.02376	0.1177	0.09056	CDK6/EREG/PDGFRB/MYB/FTH1/PDGFD/TP53INP1/NDUFS4/WNT5A/PDGFC/GAS6/PPARG/CDKN1A/FGF10/IGF1/SIRT6/MORC3	17
BP	GO:0006023	aminoglycan biosynthetic process	22/2306	115/18670	0.02377	0.1177	0.09056	IL1B/ST3GAL1/NFKB1/PDGFRB/GPC4/B4GALT3/VCAN/CHST7/HSPG2/CLTC/SDC2/CSGALNACT1/HAS2/CSGALNACT2/GALNT5/HAS1/HAS3/EXT1/ST3GAL3/SDC4/HS2ST1/ST3GAL4	22
BP	GO:0032612	interleukin-1 production	22/2306	115/18670	0.02377	0.1177	0.09056	ZC3H12A/TNFAIP3/IL1B/S1PR3/RIPK2/HSPB1/ABCA1/PANX1/GBP5/PANX2/CCL3/GSDMD/SIRPA/F2R/ERRFI1/WNT5A/HAVCR2/SERPINB1/GAS6/PYDC2/IGF1/P2RX7	22
BP	GO:2000146	negative regulation of cell motility	56/2306	349/18670	0.0238	0.1177	0.09059	IL33/CCL2/TRIB1/PPARGC1A/CITED2/RECK/FGF2/IFITM1/MCC/CORO1C/RNF20/VCL/SLIT2/NR2F2/KLF4/THBS1/ADA/KRT16/DPYSL3/CARD10/RHOB/TP53INP1/NISCH/MITF/STARD13/CYGB/DUSP3/MEOX2/ROBO1/MEF2C/PHLDB2/MIR19B2/ADORA1/SULF1/RGN/PFN2/MIR137/MIR491/SLAMF8/TACSTD2/HAS1/PTPRM/SP100/GATA3/ADARB1/SERPINE1/MIR214/DUSP10/ARHGDIB/PPARG/EPHA1/ENG/MIR218-1/STAT3/CYP19A1/ADORA3	56
BP	GO:0014065	phosphatidylinositol 3-kinase signaling	27/2306	148/18670	0.02388	0.1181	0.09083	CCL5/IER3/KIT/PIK3CD/FBXL2/PDGFRB/FYN/IRS1/KLF4/PIK3R2/PTPN13/EDN1/SEMA4D/PDGFD/F2R/TGFB2/SIRT1/NKX3-1/TNF/PEAR1/PDGFC/GATA3/PPP2R5C/PIP4K2A/IGF1/NEDD4/PRR5	27
BP	GO:0048880	sensory system development	59/2306	371/18670	0.02451	0.1211	0.09314	NINJ1/NDP/AHI1/MEIS1/C3/SLC7A11/ALDH1A3/VEGFA/BMP4/PDGFRB/SIX5/IRX5/RDH10/BCAR3/RXRA/RHOJ/BMPR2/KLF4/SMARCD3/CRYAB/CRYGS/RAB3GAP1/MYOM1/COL5A2/HIPK2/TGFB2/MITF/WNT5B/ZDHHC16/LRP5/CEP290/IMPDH2/WNT5A/SHROOM2/HES5/FJX1/CDKN1C/RAB18/FBN1/SH3PXD2B/TOPORS/CLN8/SALL2/FZD4/OSR2/PTPRM/ATP8A2/GATA3/COL4A1/ARID1A/PRDM1/MAX/RDH13/FGF10/MYH10/STAT3/COL5A1/MAB21L2/NPHP1	59
BP	GO:0048010	vascular endothelial growth factor receptor signaling pathway	19/2306	96/18670	0.02458	0.1213	0.09336	IL1B/HSPB1/MYOF/VEGFA/ROCK1/FYN/CYBA/PIK3R2/PXN/AXL/SULF1/SHB/PGF/FZD4/ROCK2/FGF10/CDC42/NEDD4/WASF2	19
BP	GO:0008016	regulation of heart contraction	42/2306	251/18670	0.02471	0.1216	0.09355	ZC3H12A/GPD1L/EPAS1/GJD3/POPDC2/GSTO1/IRX5/CALM1/PDE4D/CAMK2D/HSPB7/GCH1/ADA/EDN1/DMPK/HBEGF/TRPC1/TGFB2/RGS2/THRA/HCN4/ITPR2/RGS4/ADORA1/KCND1/CACNA1F/CACNA1B/CALM2/ATP2A2/MIR1-2/STIM1/SNTA1/NPR2/PDE4B/KCND3/ATP1A4/MYH6/NPPA/PDE5A/SRI/CASQ1/ADORA3	42
BP	GO:0045637	regulation of myeloid cell differentiation	42/2306	251/18670	0.02471	0.1216	0.09355	NFKBIA/CSF2/LIF/ID2/TRIB1/CDK6/CSF1/CEBPB/ISG15/MEIS1/PRKCA/MAFB/STAT1/IRF7/MOV10/ETS1/CCL3/FADD/THBS1/ZFP36/UBASH3B/PRMT1/KAT2B/KLF13/MITF/TMEM64/PURB/ACIN1/MEF2C/FBN1/TNF/BGLAP/RBM15/MIR125B1/HOXA9/TFE3/RBBP5/TLR3/STAT3/PIAS3/ZNF675/CBFB	42
BP	GO:0150077	regulation of neuroinflammatory response	10/2306	41/18670	0.02471	0.1216	0.09355	PTGS2/IL6/IL1B/IL33/MMP3/TNFRSF1B/CCL3/MMP9/TNF/IGF1	10
BP	GO:1903053	regulation of extracellular matrix organization	10/2306	41/18670	0.02471	0.1216	0.09355	IL6/FSCN1/PDPN/TNFRSF1B/CFLAR/ETS1/PHLDB1/HAS2/PHLDB2/ABL1	10
BP	GO:0050795	regulation of behavior	15/2306	71/18670	0.02505	0.1231	0.09475	CSF2/ADORA2A/AHI1/NPAS2/CCL3/SGIP1/ADA/EIF2AK4/ZFHX3/MEF2C/ARRDC3/ADORA1/VPS35/DLG4/STAT3	15
BP	GO:0014911	positive regulation of smooth muscle cell migration	11/2306	47/18670	0.0255	0.1242	0.09558	CCL5/PAK1/PDGFRB/SSH1/PDGFD/ITGA2/LPAR1/HAS2/DOCK4/IGF1/FOXO4	11
BP	GO:0031952	regulation of protein autophosphorylation	11/2306	47/18670	0.0255	0.1242	0.09558	VEGFA/EEF2K/CALM1/ENPP1/PDGFD/ERRFI1/PPP2R5E/CALM2/PDGFC/PPP2R5C/ENG	11
BP	GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	11/2306	47/18670	0.0255	0.1242	0.09558	NFKBIZ/ZC3H12A/CD83/RIPK2/SH3RF1/MYB/IL4R/SOCS1/GATA3/SASH3/CBFB	11
BP	GO:0048806	genitalia development	11/2306	47/18670	0.0255	0.1242	0.09558	DNAJC19/SRD5A1/ASB1/AXL/WNT5A/TP63/LGR4/PTPN11/FGF10/CYP19A1/TBX3	11
BP	GO:0061614	pri-miRNA transcription by RNA polymerase II	11/2306	47/18670	0.0255	0.1242	0.09558	BMP2/BMP4/ETS1/KLF4/TGFB2/GNL3/DDX5/PPARG/STAT3/ATOH8/NFIB	11
BP	GO:1900744	regulation of p38MAPK cascade	11/2306	47/18670	0.0255	0.1242	0.09558	BMP2/ZC3H12A/IL1B/VEGFA/CYLD/PRMT1/GADD45G/DUSP10/PER1/PJA2/GDF6	11
BP	GO:2000107	negative regulation of leukocyte apoptotic process	11/2306	47/18670	0.0255	0.1242	0.09558	CCL5/IL7R/IDO1/BMP4/IRF7/FADD/SLC39A10/ADA/AXL/BCL10/GAS6	11
BP	GO:2001239	regulation of extrinsic apoptotic signaling pathway in absence of ligand	11/2306	47/18670	0.0255	0.1242	0.09558	CSF2/IL1B/IL1A/PPP2R1B/FYN/SNAI2/BCL2L1/TNF/FGF10/EYA2/SGK3	11
BP	GO:0007269	neurotransmitter secretion	30/2306	169/18670	0.0255	0.1242	0.09558	ADORA2A/SLC22A2/PPFIA1/PNKD/STX3/BACE1/RAB3GAP1/PPT1/LIN7A/MEF2C/CDK5/SNAP47/RAB3A/SYT4/PREPL/PFN2/SLC30A1/DGKI/CACNA1B/RPH3A/ATP2A2/SNPH/STXBP1/SYT1/GRIN3A/NAPB/DVL1/LIN7C/P2RX7/PPFIA3	30
BP	GO:0060675	ureteric bud morphogenesis	14/2306	65/18670	0.02551	0.1242	0.09558	BMP2/FGF2/SIX1/VEGFA/LZTS2/BMP4/PKD2/HOXA11/SIX4/PGF/TACSTD2/GATA3/HOXB7/LGR4	14
BP	GO:0072577	endothelial cell apoptotic process	14/2306	65/18670	0.02551	0.1242	0.09558	ICAM1/TNFAIP3/CCL2/CD248/CD40/BMPR2/ITGA4/THBS1/TNF/GATA3/HLA-G/SERPINE1/ABL1/GAS6	14
BP	GO:0072665	protein localization to vacuole	14/2306	65/18670	0.02551	0.1242	0.09558	TNFAIP3/GBP1/GNPTAB/VPS37D/SH3BP4/GCC2/VPS36/VPS37C/RTN4/KPTN/ROCK2/VAMP7/M6PR/NEDD4	14
BP	GO:0001885	endothelial cell development	13/2306	59/18670	0.02579	0.1246	0.09589	ICAM1/IL1B/S1PR3/CLDN1/VEGFA/ROCK1/PDE4D/MYADM/RDX/TNF/ROCK2/ENG/TJP1	13
BP	GO:0045824	negative regulation of innate immune response	13/2306	59/18670	0.02579	0.1246	0.09589	TNFAIP3/PARP14/HLA-E/HLA-F/IRAK3/ADAR/DHX58/HAVCR2/SLAMF8/TRAFD1/HLA-G/DUSP10/PPARG	13
BP	GO:0097755	positive regulation of blood vessel diameter	13/2306	59/18670	0.02579	0.1246	0.09589	SOD2/ITGA1/BDKRB2/ADORA2A/BMPR2/GCH1/RGS2/BBS2/ADORA1/PTPRM/DOCK4/ADRB3/CPS1	13
BP	GO:2000351	regulation of endothelial cell apoptotic process	13/2306	59/18670	0.02579	0.1246	0.09589	ICAM1/TNFAIP3/CCL2/CD248/CD40/ITGA4/THBS1/TNF/GATA3/HLA-G/SERPINE1/ABL1/GAS6	13
BP	GO:0035065	regulation of histone acetylation	12/2306	53/18670	0.02581	0.1246	0.09589	IL1B/LIF/PPARGC1A/AUTS2/SET/SNAI2/RPS6KA4/SIRT1/GATA3/IWS1/SETD5/ZNF451	12
BP	GO:0038066	p38MAPK cascade	12/2306	53/18670	0.02581	0.1246	0.09589	BMP2/ZC3H12A/IL1B/VEGFA/ZFP36/CYLD/PRMT1/GADD45G/DUSP10/PER1/PJA2/GDF6	12
BP	GO:0050702	interleukin-1 beta secretion	12/2306	53/18670	0.02581	0.1246	0.09589	ZC3H12A/TNFAIP3/RIPK2/ABCA1/PANX1/GBP5/CCL3/GSDMD/WNT5A/SERPINB1/PYDC2/P2RX7	12
BP	GO:0050704	regulation of interleukin-1 secretion	12/2306	53/18670	0.02581	0.1246	0.09589	ZC3H12A/TNFAIP3/RIPK2/PANX1/PANX2/CCL3/GSDMD/WNT5A/SERPINB1/GAS6/PYDC2/P2RX7	12
BP	GO:0070228	regulation of lymphocyte apoptotic process	12/2306	53/18670	0.02581	0.1246	0.09589	CCL5/IL7R/IDO1/BMP4/FADD/SLC39A10/ADA/FNIP1/WNT5A/BCL10/P2RX7/ADAM8	12
BP	GO:1901185	negative regulation of ERBB signaling pathway	12/2306	53/18670	0.02581	0.1246	0.09589	ITGA1/GPRC5A/EREG/EPS15/TGFA/HBEGF/SPRY1/ERRFI1/DUSP3/CDC42/CBLB/RNF126	12
BP	GO:1903307	positive regulation of regulated secretory pathway	12/2306	53/18670	0.02581	0.1246	0.09589	IL4R/HLA-F/SNX4/CDK5/KCNB1/RAB3A/SYT4/ARF1/STXBP1/SYT1/VAMP7/NPPA	12
BP	GO:0002706	regulation of lymphocyte mediated immunity	27/2306	149/18670	0.02584	0.1247	0.09592	IL6/IL1B/IL7R/RSAD2/C3/TNFRSF1B/HLA-E/IL12A/IL18R1/HLA-F/CD40/FADD/HLA-A/EXOSC6/CLCF1/STAT6/TRAF2/MICB/HAVCR2/TNF/GATA3/HLA-G/NCR1/P2RX7/HLA-B/SASH3/HLA-H	27
BP	GO:0006986	response to unfolded protein	31/2306	176/18670	0.02592	0.1247	0.09597	CCL2/ERN1/HSPB1/HSPB2/DAXX/PPP1R15A/DNAJA1/TBL2/FICD/HERPUD1/DNAJB9/CCND1/LMNA/HDGF/HSPB7/WIPI1/THBS1/DCTN1/SERP2/DNAJC3/OPTN/HYOU1/SERPINH1/ASNS/SSR1/CTDSP2/RNF121/TSPYL2/TLN1/TMEM33/BFAR	31
BP	GO:0030323	respiratory tube development	31/2306	176/18670	0.02592	0.1247	0.09597	LIF/HSD11B1/PDPN/EPAS1/SLC7A11/VEGFA/BMP4/KLF2/PDGFRB/LIPA/RDH10/BMPR2/ADA/SPRY1/GATA6/CYP1A2/ERRFI1/THRA/YAP1/CRISPLD2/WNT5A/RCN3/RAB3A/TNC/PTK7/TNF/SPARC/RSPO2/CEBPA/FGF10/NFIB	31
BP	GO:0051897	positive regulation of protein kinase B signaling	31/2306	176/18670	0.02592	0.1247	0.09597	KIT/FGF2/C1QTNF1/PIK3CD/EREG/PDGFRB/FYN/IRS1/IL26/CCL3/THBS1/PIK3R2/TCF7L2/TGFA/HBEGF/MC1R/AXL/TNFAIP8L3/GDF15/TXN/TNF/FGF5/IAPP/GATA3/RTN4/GAS6/PTPN11/ENG/FGF10/MIR199A2/ADAM8	31
BP	GO:1903320	regulation of protein modification by small protein conjugation or removal	39/2306	231/18670	0.02604	0.1249	0.09607	BIRC3/ZC3H12A/TNFAIP3/TNIP1/RIPK2/BAG2/BIRC2/ISG15/DAXX/PRR7/DNAJA1/RNF20/FYN/HERPUD1/ITCH/NDFIP1/TRIB3/UBR5/CDC14B/ARRDC4/GNL3/CDK5/ARRDC3/TRIM21/DCUN1D4/UBXN1/TOPORS/PRMT3/IVNS1ABP/FKBP1A/ABL1/BCL10/UBB/NDFIP2/TICAM1/SH3RF2/MYCBP2/PIAS3/UBE2S	39
BP	GO:0010959	regulation of metal ion transport	62/2306	394/18670	0.02631	0.1249	0.09607	ICAM1/BDKRB1/CCL5/PTGS2/CXCL10/CCL2/ADORA2A/FHL1/CNKSR3/GPD1L/PDGFRB/GSTO1/RRAD/FYN/CALM1/PDE4D/CAMK2D/PKD2/CXCL11/CCL3/ANK3/CYBA/UBASH3B/CXCL9/THADA/TRPC1/F2R/GJC2/HECW2/GEM/STAC/RGS4/ADORA1/RGN/ARF1/SLC30A1/MYLK/P2RX3/CACNA1B/CAMK2G/YWHAH/CALM2/ACTN4/MIR1-2/STIM1/FKBP1A/SPINK1/DIAPH1/SNTA1/ABL1/PDE4B/ORAI1/PER1/NPPA/SIK1/OSR1/SRI/P2RX7/CASQ1/NEDD4/HOMER2/ADRA2A	62
BP	GO:0001660	fever generation	4/2306	10/18670	0.02635	0.1249	0.09607	PTGS2/IL1B/IL1A/TNF	4
BP	GO:0007016	cytoskeletal anchoring at plasma membrane	4/2306	10/18670	0.02635	0.1249	0.09607	ANK3/EPB41L3/FLNB/TLN1	4
BP	GO:0007220	Notch receptor processing	4/2306	10/18670	0.02635	0.1249	0.09607	APH1B/PSENEN/GALNT11/DNER	4
BP	GO:0010749	regulation of nitric oxide mediated signal transduction	4/2306	10/18670	0.02635	0.1249	0.09607	VEGFA/THBS1/SPINK1/PDE5A	4
BP	GO:0032463	negative regulation of protein homooligomerization	4/2306	10/18670	0.02635	0.1249	0.09607	CRYAB/VPS35/CRBN/IAPP	4
BP	GO:0033210	leptin-mediated signaling pathway	4/2306	10/18670	0.02635	0.1249	0.09607	UGCG/BBS2/SIRT1/STAT3	4
BP	GO:0039530	MDA-5 signaling pathway	4/2306	10/18670	0.02635	0.1249	0.09607	IFIH1/DDX60/IRF7/DHX58	4
BP	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity	4/2306	10/18670	0.02635	0.1249	0.09607	EREG/TGFA/ADORA1/ADRA2A	4
BP	GO:0051014	actin filament severing	4/2306	10/18670	0.02635	0.1249	0.09607	DSTN/GSN/GMFB/MYH9	4
BP	GO:0070099	regulation of chemokine-mediated signaling pathway	4/2306	10/18670	0.02635	0.1249	0.09607	CCL5/SLIT2/EDN1/ROBO1	4
BP	GO:0070341	fat cell proliferation	4/2306	10/18670	0.02635	0.1249	0.09607	PID1/FTO/FGF10/TFDP1	4
BP	GO:0070344	regulation of fat cell proliferation	4/2306	10/18670	0.02635	0.1249	0.09607	PID1/FTO/FGF10/TFDP1	4
BP	GO:0071233	cellular response to leucine	4/2306	10/18670	0.02635	0.1249	0.09607	SESN1/SESN3/UBR1/SESN2	4
BP	GO:0071670	smooth muscle cell chemotaxis	4/2306	10/18670	0.02635	0.1249	0.09607	PDGFRB/SLIT2/PDGFD/LPAR1	4
BP	GO:0090037	positive regulation of protein kinase C signaling	4/2306	10/18670	0.02635	0.1249	0.09607	VEGFA/CD40/MC1R/WNT5A	4
BP	GO:1903789	regulation of amino acid transmembrane transport	4/2306	10/18670	0.02635	0.1249	0.09607	ARL6IP5/RGS2/RGS4/OSR1	4
BP	GO:1990253	cellular response to leucine starvation	4/2306	10/18670	0.02635	0.1249	0.09607	SESN1/EIF2AK4/SESN3/SESN2	4
BP	GO:2000109	regulation of macrophage apoptotic process	4/2306	10/18670	0.02635	0.1249	0.09607	CCL5/IRF7/MEF2C/SIRT1	4
BP	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	17/2306	84/18670	0.02647	0.1253	0.09638	BIRC3/PTGS2/SH3RF1/ADORA2A/BIRC2/TNFAIP8/VEGFA/CFLAR/CD44/HERPUD1/KLF4/THBS1/CRYAB/FNIP1/MMP9/MAGEA3/GAS6	17
BP	GO:0048144	fibroblast proliferation	17/2306	84/18670	0.02647	0.1253	0.09638	CDK6/EREG/PDGFRB/MYB/FTH1/PDGFD/TP53INP1/NDUFS4/WNT5A/PDGFC/GAS6/PPARG/CDKN1A/FGF10/IGF1/SIRT6/MORC3	17
BP	GO:0060996	dendritic spine development	19/2306	97/18670	0.02715	0.1284	0.09876	SIPA1L1/DBN1/CAPRIN1/EEF2K/PLK2/LPAR1/MEF2C/ITPKA/CDK5/ARF6/BHLHB9/ARF1/PDLIM5/DLG4/ASAP1/ACTR2/CDC42/DVL1/NGEF	19
BP	GO:0044344	cellular response to fibroblast growth factor stimulus	26/2306	143/18670	0.02728	0.1289	0.09915	CCL5/CCL2/FGF2/COL1A1/CD44/THBS1/ZFP36/SULF2/FGFRL1/ZFP36L2/SPRY1/FLRT2/WNT5A/SULF1/SHISA2/FLRT3/MIR1-2/FGF5/GATA3/CPS1/NPTN/PTPN11/FGF10/SHOC2/GTF2F2/CRKL	26
BP	GO:1903531	negative regulation of secretion by cell	36/2306	211/18670	0.02731	0.1289	0.09919	ZC3H12A/TNFAIP3/IL1B/LIF/IL33/RSAD2/TNFRSF1B/HLA-F/PNKD/LRRC32/IRS1/GBP1/RHBDF2/EDN1/HADH/INHBB/F2R/SERGEF/SRGN/ADORA1/KCNB1/ANXA4/SYT4/SLC30A1/ABAT/TNF/SYTL4/SERPINB1/PPP3CA/LGR4/RAB11FIP1/GAS6/PTPN11/PYDC2/MAPKBP1/ADRA2A	36
BP	GO:0032413	negative regulation of ion transmembrane transporter activity	16/2306	78/18670	0.02735	0.1289	0.09919	GSTO1/RRAD/CALM1/CAMK2D/PKD2/ANK3/THADA/HECW2/MMP9/GEM/CALM2/MIR1-2/OSR1/SRI/NEDD4/ADRA2A	16
BP	GO:0033143	regulation of intracellular steroid hormone receptor signaling pathway	16/2306	78/18670	0.02735	0.1289	0.09919	DAB2/PAK1/RNF14/LBH/ARNTL/YAP1/CARM1/SIRT1/TP63/DDX5/KCTD6/GPAM/UFSP2/NCOR2/PER1/CBFB	16
BP	GO:0099643	signal release from synapse	30/2306	170/18670	0.02742	0.1292	0.09938	ADORA2A/SLC22A2/PPFIA1/PNKD/STX3/BACE1/RAB3GAP1/PPT1/LIN7A/MEF2C/CDK5/SNAP47/RAB3A/SYT4/PREPL/PFN2/SLC30A1/DGKI/CACNA1B/RPH3A/ATP2A2/SNPH/STXBP1/SYT1/GRIN3A/NAPB/DVL1/LIN7C/P2RX7/PPFIA3	30
BP	GO:0030100	regulation of endocytosis	46/2306	281/18670	0.02766	0.1298	0.09983	IL1B/PPP3CC/CCL2/EHD4/AHI1/DAB2/C3/VEGFA/EEF2K/ROCK1/IL15RA/VAMP4/ANKRD13A/MKLN1/SGIP1/CYBA/IL15/PPT1/SDCBP/SIRPA/ITGA2/RAB4A/FLOT1/CLIP3/AXL/WNT5A/MYO18A/ARF6/SYT4/ARF1/TNF/APPL2/ACTN4/DLG4/PTX3/PPP3CA/SERPINE1/ABL1/GAS6/TOR1A/PPARG/MIB1/MIR199A2/RAB31/PICALM/SNX3	46
BP	GO:0010742	macrophage derived foam cell differentiation	9/2306	36/18670	0.02777	0.1298	0.09983	NFKBIA/CSF2/NFKB1/ABCA1/CSF1/STAT1/ABCA5/SOAT1/PPARG	9
BP	GO:0014808	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	9/2306	36/18670	0.02777	0.1298	0.09983	GSTO1/CALM1/PDE4D/CAMK2D/CCL3/CALM2/MIR1-2/SRI/CASQ1	9
BP	GO:0034390	smooth muscle cell apoptotic process	9/2306	36/18670	0.02777	0.1298	0.09983	SOD2/IL12A/PDE1A/STK4/EDN1/SIRT1/MIR1-2/PPARG/IGF1	9
BP	GO:0034391	regulation of smooth muscle cell apoptotic process	9/2306	36/18670	0.02777	0.1298	0.09983	SOD2/IL12A/PDE1A/STK4/EDN1/SIRT1/MIR1-2/PPARG/IGF1	9
BP	GO:0035872	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	9/2306	36/18670	0.02777	0.1298	0.09983	NFKBIA/BIRC3/TNFAIP3/IRAK2/RIPK2/BIRC2/ITCH/CYLD/UBB	9
BP	GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	9/2306	36/18670	0.02777	0.1298	0.09983	THBS1/SULF2/SPRY1/WNT5A/SULF1/SHISA2/MIR1-2/GATA3/NPTN	9
BP	GO:0060428	lung epithelium development	9/2306	36/18670	0.02777	0.1298	0.09983	BMP4/KLF2/GATA6/ERRFI1/THRA/YAP1/RCN3/FGF10/NFIB	9
BP	GO:0090077	foam cell differentiation	9/2306	36/18670	0.02777	0.1298	0.09983	NFKBIA/CSF2/NFKB1/ABCA1/CSF1/STAT1/ABCA5/SOAT1/PPARG	9
BP	GO:1901020	negative regulation of calcium ion transmembrane transporter activity	9/2306	36/18670	0.02777	0.1298	0.09983	GSTO1/RRAD/CALM1/PKD2/THADA/GEM/CALM2/SRI/ADRA2A	9
BP	GO:0019054	modulation by virus of host process	7/2306	25/18670	0.0279	0.1298	0.09983	ZC3H12A/CCL8/EIF2AK4/KPNA3/ATG7/BCL2L1/KPNA2	7
BP	GO:0035336	long-chain fatty-acyl-CoA metabolic process	7/2306	25/18670	0.0279	0.1298	0.09983	ELOVL5/ELOVL7/ACSL5/ELOVL2/HSD17B12/FAR1/ELOVL3	7
BP	GO:0043951	negative regulation of cAMP-mediated signaling	7/2306	25/18670	0.0279	0.1298	0.09983	PDE4D/RGS2/LPAR1/ARRDC3/MRAP2/PDE3B/CRTC3	7
BP	GO:0061050	regulation of cell growth involved in cardiac muscle cell development	7/2306	25/18670	0.0279	0.1298	0.09983	PAK1/EDN1/RGS2/MIR19B2/RGS4/MIR199A2/IGF1	7
BP	GO:0072202	cell differentiation involved in metanephros development	7/2306	25/18670	0.0279	0.1298	0.09983	LIF/STAT1/BMP4/WWTR1/YAP1/LGR4/OSR1	7
BP	GO:0072273	metanephric nephron morphogenesis	7/2306	25/18670	0.0279	0.1298	0.09983	LIF/STAT1/BMP4/PDGFRB/PKD2/HES5/LGR4	7
BP	GO:0072677	eosinophil migration	7/2306	25/18670	0.0279	0.1298	0.09983	CCL5/CCL2/CCL8/CCL7/CCL3/CCL1/ADAM8	7
BP	GO:0071774	response to fibroblast growth factor	27/2306	150/18670	0.02793	0.1298	0.09985	CCL5/CCL2/FGF2/COL1A1/CD44/THBS1/ZFP36/SULF2/FGFRL1/ZFP36L2/SPRY1/FLRT2/WNT5A/SULF1/TNC/SHISA2/FLRT3/MIR1-2/FGF5/GATA3/CPS1/NPTN/PTPN11/FGF10/SHOC2/GTF2F2/CRKL	27
BP	GO:0048017	inositol lipid-mediated signaling	32/2306	184/18670	0.02817	0.1308	0.1006	CCL5/PLD1/IER3/KIT/NPR3/PIK3CD/FBXL2/PLCE1/PDGFRB/FYN/IRS1/KLF4/PIK3R2/PTPN13/EDN1/SEMA4D/PDGFD/F2R/TGFB2/SIRT1/TNFAIP8L3/NKX3-1/GSN/TNF/PEAR1/PDGFC/GATA3/PPP2R5C/PIP4K2A/IGF1/NEDD4/PRR5	32
BP	GO:0071214	cellular response to abiotic stimulus	53/2306	331/18670	0.02822	0.1308	0.1007	AKR1B1/NAMPT/PTGS2/IL1B/RELB/NFKB1/BDKRB2/IRF1/SLC2A1/SLC38A2/CNN2/COL1A1/CD40/CALM1/FAS/PKD2/NET1/CDC25A/FADD/CYBA/MAP3K1/MAPK13/EIF2AK4/CRYAB/MC1R/RHOB/TP53INP1/DDB2/ITGA2/ERRFI1/SNAI2/YAP1/LRRC8E/GPR68/SIRT1/BCL2L1/MYLK/MAP3K2/TNFRSF10B/C9orf116/TLR3/GATA3/GTF2H5/NUCKS1/BCL10/MCOLN1/CDKN1A/PTPN11/ENG/NPPA/NEDD4/NMT2/ST20	53
BP	GO:0104004	cellular response to environmental stimulus	53/2306	331/18670	0.02822	0.1308	0.1007	AKR1B1/NAMPT/PTGS2/IL1B/RELB/NFKB1/BDKRB2/IRF1/SLC2A1/SLC38A2/CNN2/COL1A1/CD40/CALM1/FAS/PKD2/NET1/CDC25A/FADD/CYBA/MAP3K1/MAPK13/EIF2AK4/CRYAB/MC1R/RHOB/TP53INP1/DDB2/ITGA2/ERRFI1/SNAI2/YAP1/LRRC8E/GPR68/SIRT1/BCL2L1/MYLK/MAP3K2/TNFRSF10B/C9orf116/TLR3/GATA3/GTF2H5/NUCKS1/BCL10/MCOLN1/CDKN1A/PTPN11/ENG/NPPA/NEDD4/NMT2/ST20	53
BP	GO:0010906	regulation of glucose metabolic process	22/2306	117/18670	0.02843	0.1317	0.1013	PPARGC1A/C1QTNF1/FOXO1/PPP1R3F/ACACB/COX11/IRS1/NFE2L1/DYRK2/PHLDA2/ENPP1/PMAIP1/KAT2B/SIRT1/RGN/SESN2/DUSP12/PDK3/SLC35B4/SIK1/IGF1/GNMT	22
BP	GO:1905952	regulation of lipid localization	28/2306	157/18670	0.02851	0.132	0.1015	NFKBIA/ZC3H12A/IL6/IL1B/NFKB1/ABCA1/C1QTNF1/C3/ACACB/MYB/FABP3/FTO/THBS1/EDN1/LIPG/EHD1/SIRT1/MIR19B2/NKX3-1/TNF/ATP8A2/ABHD5/PRKCD/SCP2/PPARG/PTPN11/P2RX7/CYP19A1	28
BP	GO:0070371	ERK1 and ERK2 cascade	51/2306	317/18670	0.02857	0.132	0.1016	CCL20/BMP2/ICAM1/CCL5/TNIP1/IL1B/LIF/RIPK2/CCL2/CCL8/CCL7/KIT/FGF2/CNKSR3/PRKCA/DUSP6/CFLAR/BMP4/PDGFRB/CCL3L3/CD44/IL26/KLF4/CCL3/GBP1/OXTR/BMPER/AKAP12/ZFP36L2/PDGFD/SIRPA/F2R/CCL1/SPRY1/ERRFI1/DUSP3/TNFAIP8L3/HAVCR2/TNF/PDGFC/NPTN/ABL1/DUSP10/GAS6/PTPN11/FGF10/ROS1/IGF1/SERPINF2/CRKL/GLIPR2	51
BP	GO:0010923	negative regulation of phosphatase activity	20/2306	104/18670	0.02859	0.132	0.1016	ENSA/PPP4R4/PPP1R15A/ROCK1/SET/SEMA4D/PPP1R9B/TGFB2/PHACTR2/CCDC8/RGN/TNF/FKBP1A/TMEM225/ROCK2/ELL/PPP1R14C/FARP1/SH3RF2/MYO1D	20
BP	GO:0019233	sensory perception of pain	20/2306	104/18670	0.02859	0.132	0.1016	BDKRB1/PTGS2/CCL2/GIP/FYN/BACE1/CCL3/EDN1/NIPSNAP1/MC1R/F2R/ITGA2/CDK5/ADORA1/P2RX3/CNR2/IAPP/MMP24/NMUR2/P2RX7	20
BP	GO:0006513	protein monoubiquitination	14/2306	66/18670	0.02882	0.1328	0.1022	BIRC2/FBXL2/RNF20/TRIM25/TRIM37/DDB2/TRIM21/UBE2E1/UBE2T/TOPORS/UBB/UBE4B/RNF126/ZNF598	14
BP	GO:0051926	negative regulation of calcium ion transport	14/2306	66/18670	0.02882	0.1328	0.1022	ICAM1/PTGS2/GSTO1/RRAD/CALM1/PKD2/THADA/GEM/SLC30A1/CALM2/MIR1-2/SPINK1/SRI/ADRA2A	14
BP	GO:1905207	regulation of cardiocyte differentiation	14/2306	66/18670	0.02882	0.1328	0.1022	BMP2/BMP4/PAK1/EDN1/TGFB2/RGS2/GATA6/MEF2C/MIR19B2/RGS4/MIR1-2/MIR199A2/IGF1/FZD7	14
BP	GO:0010470	regulation of gastrulation	10/2306	42/18670	0.02896	0.1331	0.1024	MYADM/KLF4/MBP/COL5A2/PHLDB1/PHLDB2/MIR1-2/OSR1/COL5A1/FZD7	10
BP	GO:0032515	negative regulation of phosphoprotein phosphatase activity	13/2306	60/18670	0.02932	0.1331	0.1024	ENSA/PPP4R4/PPP1R15A/ROCK1/SET/PPP1R9B/PHACTR2/RGN/TNF/FKBP1A/ROCK2/PPP1R14C/SH3RF2	13
BP	GO:0034404	nucleobase-containing small molecule biosynthetic process	38/2306	226/18670	0.02935	0.1331	0.1024	PPARGC1A/SLC2A6/TYMP/HK2/ENO2/ADPGK/PDE4D/NUP133/PDE1A/AMPD3/PGM2L1/NUDT18/NUDT7/ADA/ACAT1/NT5C2/ENPP1/NUDT11/NME5/NUDT1/ABCD1/IMPDH2/GUK1/MTAP/PRTFDC1/PGAM4/MBD4/PDE4B/TK2/NUP35/PDE5A/DCK/IGF1/STAT3/ALDOC/P2RX7/HINT1/SIRT6	38
BP	GO:0060401	cytosolic calcium ion transport	30/2306	171/18670	0.02946	0.1331	0.1024	BDKRB1/CXCL10/FGF2/PLCE1/GSTO1/FYN/CALM1/PDE4D/CAMK2D/PKD2/CXCL11/CCL3/CYBA/UBASH3B/CXCL9/TRPC1/F2R/ITPR2/TPCN1/P2RX3/CALM2/ATP2A2/MIR1-2/FKBP1A/DIAPH1/ABL1/MCOLN1/SRI/P2RX7/CASQ1	30
BP	GO:0007043	cell-cell junction assembly	23/2306	124/18670	0.02946	0.1331	0.1024	CLDN1/FSCN1/PRKCA/GJD3/ROCK1/RAB13/CNTNAP1/VCL/EPB41L3/SNAI2/GJB2/UGT8/TNF/ACTN4/PKP4/ROCK2/PKN2/TJP1/CDH4/TLN1/PDCD6IP/NPHP1/CBFB	23
BP	GO:0010592	positive regulation of lamellipodium assembly	6/2306	20/18670	0.0295	0.1331	0.1024	FSCN1/AUTS2/AKIRIN1/ARPC2/CDC42/WASF2	6
BP	GO:0034104	negative regulation of tissue remodeling	6/2306	20/18670	0.0295	0.1331	0.1024	TNFAIP3/IL6/UBASH3B/IAPP/TNFRSF11B/P2RX7	6
BP	GO:0042474	middle ear morphogenesis	6/2306	20/18670	0.0295	0.1331	0.1024	SIX1/INSIG2/EDN1/PRKRA/OSR2/OSR1	6
BP	GO:0045019	negative regulation of nitric oxide biosynthetic process	6/2306	20/18670	0.0295	0.1331	0.1024	ZC3H12A/GLA/SIRPA/RGN/ROCK2/MIR199A2	6
BP	GO:0046823	negative regulation of nucleocytoplasmic transport	6/2306	20/18670	0.0295	0.1331	0.1024	RAB23/CDK5/TXN/SP100/PKIG/FERMT1	6
BP	GO:0048745	smooth muscle tissue development	6/2306	20/18670	0.0295	0.1331	0.1024	SIX1/BMP4/PKD2/MYLK/ENG/OSR1	6
BP	GO:0051797	regulation of hair follicle development	6/2306	20/18670	0.0295	0.1331	0.1024	MSX2/TGFB2/WNT5A/TNF/FST/FERMT1	6
BP	GO:1904406	negative regulation of nitric oxide metabolic process	6/2306	20/18670	0.0295	0.1331	0.1024	ZC3H12A/GLA/SIRPA/RGN/ROCK2/MIR199A2	6
BP	GO:1905523	positive regulation of macrophage migration	6/2306	20/18670	0.0295	0.1331	0.1024	CCL5/CSF1/CMKLR1/CCL3/THBS1/AKIRIN1	6
BP	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	11/2306	48/18670	0.0295	0.1331	0.1024	BMP2/DAB2/BMP4/BMPR2/INHBB/SDCBP/TGFB2/GDF5/GDF15/ENG/GDF6	11
BP	GO:0061647	histone H3-K9 modification	11/2306	48/18670	0.0295	0.1331	0.1024	JARID2/MYB/LMNA/KAT2B/SETDB2/SIRT1/GATA3/SETD5/ZNF451/SIRT6/ARID4A	11
BP	GO:1904064	positive regulation of cation transmembrane transport	26/2306	144/18670	0.0295	0.1331	0.1024	BDKRB1/CXCL10/CCL2/CNKSR3/CTSS/GSTO1/CALM1/PKD2/CXCL11/ANK3/CXCL9/COX17/TRPC1/F2R/GJC2/STAC/RGN/ARF1/CALM2/ACTN4/MIR1-2/STIM1/ABL1/NPPA/SRI/CASQ1	26
BP	GO:1904645	response to amyloid-beta	12/2306	54/18670	0.02958	0.1331	0.1024	ICAM1/NAMPT/VCAM1/MMP3/BCL2L2/FYN/BACE1/ITGA4/MMP9/CDK5/CACNA1B/IGF1	12
BP	GO:0010759	positive regulation of macrophage chemotaxis	5/2306	15/18670	0.0296	0.1331	0.1024	CCL5/CSF1/CMKLR1/THBS1/AKIRIN1	5
BP	GO:0030730	sequestering of triglyceride	5/2306	15/18670	0.0296	0.1331	0.1024	IL1B/ENPP1/TNF/ABHD5/PPARG	5
BP	GO:0032352	positive regulation of hormone metabolic process	5/2306	15/18670	0.0296	0.1331	0.1024	IL1B/PPARGC1A/RDH10/TNF/GATA3	5
BP	GO:0033008	positive regulation of mast cell activation involved in immune response	5/2306	15/18670	0.0296	0.1331	0.1024	IL4R/SNX4/STXBP1/VAMP7/NPPA	5
BP	GO:0034111	negative regulation of homotypic cell-cell adhesion	5/2306	15/18670	0.0296	0.1331	0.1024	C1QTNF1/UBASH3B/RDX/ABAT/PRKCD	5
BP	GO:0034616	response to laminar fluid shear stress	5/2306	15/18670	0.0296	0.1331	0.1024	ABCA1/KLF2/ETS1/KLF4/ASS1	5
BP	GO:0043101	purine-containing compound salvage	5/2306	15/18670	0.0296	0.1331	0.1024	AMPD3/ADA/MTAP/PRTFDC1/DCK	5
BP	GO:0043306	positive regulation of mast cell degranulation	5/2306	15/18670	0.0296	0.1331	0.1024	IL4R/SNX4/STXBP1/VAMP7/NPPA	5
BP	GO:0046321	positive regulation of fatty acid oxidation	5/2306	15/18670	0.0296	0.1331	0.1024	PPARGC1A/IRS1/CPT1A/ABCD1/PPARG	5
BP	GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	5/2306	15/18670	0.0296	0.1331	0.1024	GSTO1/CALM1/PKD2/CALM2/SRI	5
BP	GO:0060099	regulation of phagocytosis, engulfment	5/2306	15/18670	0.0296	0.1331	0.1024	C3/ITGA2/APPL2/PPARG/RAB31	5
BP	GO:0071599	otic vesicle development	5/2306	15/18670	0.0296	0.1331	0.1024	AHI1/SIX1/CEP290/GATA3/FGF10	5
BP	GO:1901841	regulation of high voltage-gated calcium channel activity	5/2306	15/18670	0.0296	0.1331	0.1024	RRAD/GEM/PDE4B/NPPA/SRI	5
BP	GO:1905065	positive regulation of vascular smooth muscle cell differentiation	5/2306	15/18670	0.0296	0.1331	0.1024	SOD2/KIT/MIR1-2/MIR125B1/ENG	5
BP	GO:1905203	regulation of connective tissue replacement	5/2306	15/18670	0.0296	0.1331	0.1024	ROCK1/PPP3CA/ROCK2/MIR214/MIR199A2	5
BP	GO:2001185	regulation of CD8-positive, alpha-beta T cell activation	5/2306	15/18670	0.0296	0.1331	0.1024	SH3RF1/IRF1/HLA-E/SOCS1/CBFB	5
BP	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	19/2306	98/18670	0.02991	0.1343	0.1034	SOD2/BID/PTGS2/BDKRB2/HSPB1/DNAJA1/PPIF/BCL2L2/CD44/HERPUD1/GRINA/NME5/SNAI2/MMP9/SIRT1/BCL2L1/HYOU1/IVNS1ABP/MAGEA3	19
BP	GO:0035966	response to topologically incorrect protein	34/2306	199/18670	0.03067	0.1377	0.1059	CCL2/ERN1/HSPB1/HSPB2/DAXX/PPP1R15A/DNAJA1/TBL2/FICD/HERPUD1/DNAJB9/CCND1/LMNA/HDGF/HSPB7/WIPI1/THBS1/DCTN1/SERP2/DNAJC3/RNF5/OPTN/HYOU1/SERPINH1/ASNS/SSR1/CTDSP2/TOR1A/RNF121/TSPYL2/TLN1/RNF126/TMEM33/BFAR	34
BP	GO:0010458	exit from mitosis	8/2306	31/18670	0.031	0.1384	0.1065	CHMP4B/CDC14B/PPP1R9B/CDKN1C/EPS8/CDC23/UBE2S/NPM2	8
BP	GO:0033198	response to ATP	8/2306	31/18670	0.031	0.1384	0.1065	PTGS2/IL1B/PANX1/P2RY11/SSH1/P2RX3/PDXP/P2RX7	8
BP	GO:0034694	response to prostaglandin	8/2306	31/18670	0.031	0.1384	0.1065	PTGFR/EDN1/PTGER2/ACACA/AKAP8/TNC/PPARG/GNG2	8
BP	GO:0048710	regulation of astrocyte differentiation	8/2306	31/18670	0.031	0.1384	0.1065	BMP2/IL6/GPR37L1/LIF/ID2/IL6ST/CLCF1/HES5	8
BP	GO:0090075	relaxation of muscle	8/2306	31/18670	0.031	0.1384	0.1065	PDE4D/CAMK2D/RGS2/ADORA1/ATP2A2/PDE4B/PDE5A/SRI	8
BP	GO:1903319	positive regulation of protein maturation	8/2306	31/18670	0.031	0.1384	0.1065	IL1B/BAG2/C3/NKD2/TNP2/GSN/MYH9/ADAM8	8
BP	GO:2000406	positive regulation of T cell migration	8/2306	31/18670	0.031	0.1384	0.1065	CCL20/CCL5/CXCL10/TNFRSF14/FADD/ITGA4/WNT5A/ADAM8	8
BP	GO:0050680	negative regulation of epithelial cell proliferation	29/2306	165/18670	0.03119	0.1391	0.107	CCL2/CDK6/MCC/STAT1/EREG/BMP4/NR2F2/IL26/LIMS2/THBS1/TGFB2/SNAI2/GDF5/ROBO1/MEF2C/VDR/WNT5A/NKX3-1/SULF1/RGN/CDKN1C/TNF/SPARC/PTPRM/GATA3/DUSP10/PPARG/ATOH8/NFIB	29
BP	GO:0071559	response to transforming growth factor beta	42/2306	255/18670	0.0312	0.1391	0.107	CLDN1/PPARGC1A/CITED2/DAB2/PDCD5/ROCK1/CFLAR/COL1A1/FYN/LRRC32/ITGB5/BMPR2/THBS1/EDN1/PXN/ZFP36L2/SDCBP/HIPK2/PDGFD/SOX5/TGFB2/ZFHX3/GDF5/MEF2C/SIRT1/WNT5A/GDF15/CDKN1C/FBN1/APPL2/FERMT2/LTBP2/ZYX/COL1A2/ROCK2/UBB/ENG/FERMT1/USP9X/ZNF451/CRKL/SMAD9	42
BP	GO:2000117	negative regulation of cysteine-type endopeptidase activity	18/2306	92/18670	0.03125	0.1392	0.1071	BIRC3/PTGS2/SH3RF1/ADORA2A/BIRC2/TNFAIP8/VEGFA/CFLAR/CD44/HERPUD1/KLF4/THBS1/CRYAB/FNIP1/CAST/MMP9/MAGEA3/GAS6	18
BP	GO:0051249	regulation of lymphocyte activation	74/2306	485/18670	0.03128	0.1393	0.1072	NFKBIZ/ZC3H12A/TNFAIP3/CCL5/IL6/CD70/VCAM1/MAP3K8/IL1B/CD83/RIPK2/CCL2/ID2/SH3RF1/ADORA2A/IRF1/TNFSF9/CEBPB/IL7R/TNFRSF14/PDCD1LG2/TNFRSF1B/AHR/IDO1/IL6ST/BMP4/TNFSF13B/PAK1/HLA-E/IL12A/MYB/IL4R/SOCS1/HLA-F/CD40/FYN/LRRC32/FADD/SLC39A10/IL15/CYLD/ADA/EXOSC6/ZFP36L2/MAD1L1/SIRPA/EBI3/CLCF1/STAT6/DUSP3/EFNB1/AXL/MEF2C/GSN/HAVCR2/SLAMF8/GATA3/HLA-G/SDC4/PRDM1/ABL1/BCL10/DUSP10/GAS6/CDKN1A/PTPN11/FGF10/TICAM1/CDC42/PDE5A/IGF1/SASH3/ADAM8/CBFB	74
BP	GO:0033138	positive regulation of peptidyl-serine phosphorylation	20/2306	105/18670	0.03135	0.1394	0.1073	PTGS2/IL6/LIF/RIPK2/VEGFA/PAK1/CD44/BCAR3/FNIP2/STK4/FNIP1/SMYD3/WNT5A/ARAF/MTCP1/PFN2/TXN/TNF/TRIM6/GAS6	20
BP	GO:0055017	cardiac muscle tissue growth	20/2306	105/18670	0.03135	0.1394	0.1073	FGF2/MEIS1/JARID2/PAK1/RXRA/PIM1/EDN1/TGFB2/RGS2/GATA6/YAP1/MEF2C/MIR19B2/RGS4/PDLIM5/MIR1-2/NPPA/MIR199A2/IGF1/SIRT6	20
BP	GO:0030239	myofibril assembly	15/2306	73/18670	0.03152	0.1397	0.1075	CFLAR/PDGFRB/ACTC1/EDN1/MYOM1/SIX4/MEF2C/MYOM3/MIR1-2/KRT19/TMOD2/MYH6/MYH10/ACTG1/CASQ1	15
BP	GO:0043627	response to estrogen	15/2306	73/18670	0.03152	0.1397	0.1075	CITED2/PDGFRB/IL4R/TRIM25/CCND1/SRD5A1/CYP27B1/GATA6/ABCC2/BGLAP/RBBP5/KRT19/GATA3/PPARG/TNFRSF11B	15
BP	GO:1903524	positive regulation of blood circulation	15/2306	73/18670	0.03152	0.1397	0.1075	ICAM1/PTGS2/PDE4D/GCH1/OXTR/ADA/EDN1/PTGER2/F2R/TGFB2/RGS2/RGS4/ATP2A2/MIR1-2/NPPA	15
BP	GO:1903779	regulation of cardiac conduction	15/2306	73/18670	0.03152	0.1397	0.1075	CALM1/PDE4D/CAMK2D/DMPK/TRPC1/ITPR2/CALM2/ATP2A2/MIR1-2/STIM1/NPR2/ATP1A4/NPPA/SRI/CASQ1	15
BP	GO:0048662	negative regulation of smooth muscle cell proliferation	14/2306	67/18670	0.03243	0.1435	0.1104	SOD2/TNFAIP3/TRIB1/PPARGC1A/NPR3/IL12A/KLF4/IL15/MEF2C/MIR137/MIR1-2/MIR214/PPARG/CDKN1A	14
BP	GO:0048747	muscle fiber development	14/2306	67/18670	0.03243	0.1435	0.1104	FLNC/SIX1/MYOF/VEGFA/BMP4/MYOM1/SGCD/MYOM3/BIN3/CHRNB1/PPP3CA/MYH6/SGCB/DNER	14
BP	GO:1903391	regulation of adherens junction organization	14/2306	67/18670	0.03243	0.1435	0.1104	CORO1C/VEGFA/ROCK1/IQSEC1/THBS1/RDX/DUSP3/PHLDB2/ARF6/COL16A1/SDC4/MAPRE2/ABL1/ROCK2	14
BP	GO:0032675	regulation of interleukin-6 production	27/2306	152/18670	0.03249	0.1436	0.1105	ZC3H12A/TNFAIP3/IL6/IL1B/RIPK2/IL33/IFIH1/CEBPB/EREG/KLF2/IRAK3/DDX58/CYBA/MAPK13/MBP/SIRPA/F2R/WNT5A/HAVCR2/TNF/TLR3/GAS6/PTPN11/TICAM1/STAT3/P2RX7/CAPN2	27
BP	GO:0032760	positive regulation of tumor necrosis factor production	17/2306	86/18670	0.03259	0.1439	0.1107	RIPK2/HSPB1/IFIH1/IFNGR1/HLA-E/DDX58/CCL3/FADD/CYBA/THBS1/AKAP12/WNT5A/HAVCR2/TLR3/PTPN11/TICAM1/SASH3	17
BP	GO:0051817	modification of morphology or physiology of other organism involved in symbiotic interaction	21/2306	112/18670	0.03263	0.1441	0.1108	CXCL6/ZC3H12A/CCL5/TNIP1/CCL8/FBXL2/RAB9A/CALM1/RXRA/CCL3/EIF2AK4/HIPK2/KPNA3/IGF2R/ATG7/BCL2L1/CALM2/PTX3/ZNF639/NUCKS1/KPNA2	21
BP	GO:0051251	positive regulation of lymphocyte activation	53/2306	334/18670	0.03276	0.1445	0.1112	NFKBIZ/CCL5/IL6/CD70/VCAM1/MAP3K8/IL1B/CD83/RIPK2/CCL2/TNFSF9/IL7R/TNFRSF14/PDCD1LG2/IL6ST/TNFSF13B/PAK1/HLA-E/IL12A/MYB/IL4R/SOCS1/HLA-F/CD40/FYN/FADD/SLC39A10/IL15/CYLD/ADA/EXOSC6/SIRPA/EBI3/CLCF1/STAT6/EFNB1/AXL/MEF2C/HAVCR2/GATA3/HLA-G/BCL10/DUSP10/GAS6/CDKN1A/PTPN11/FGF10/TICAM1/CDC42/IGF1/SASH3/ADAM8/CBFB	53
BP	GO:1903514	release of sequestered calcium ion into cytosol by endoplasmic reticulum	9/2306	37/18670	0.0328	0.1446	0.1113	GSTO1/CALM1/PDE4D/CAMK2D/CCL3/CALM2/MIR1-2/SRI/CASQ1	9
BP	GO:0099003	vesicle-mediated transport in synapse	35/2306	207/18670	0.03287	0.1448	0.1114	PPP3CC/ADORA2A/ROCK1/EPS15/VAMP4/STX3/BACE1/STX6/RAB3GAP1/LIN7A/CDK5/SNAP47/VPS35/RAB3A/ARF6/SYT4/ARF1/PREPL/PFN2/DGKI/ACTB/ATP2A2/SNPH/STXBP1/SYT1/GRIN3A/TOR1A/AP3S1/NAPB/CNIH2/DVL1/ACTG1/P2RX7/PPFIA3/PICALM	35
BP	GO:0003158	endothelium development	24/2306	132/18670	0.03292	0.1449	0.1115	ICAM1/IL1B/S1PR3/CLDN1/CXCL10/PDPN/VEGFA/ROCK1/BMP4/PDE4D/NR2F2/BMPR2/MYADM/EDF1/RDX/RHOB/STARD13/FOXJ2/TNF/MIR1-2/ROCK2/ENG/TJP1/ATOH8	24
BP	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	37/2306	221/18670	0.03307	0.1455	0.1119	GPR37L1/S1PR3/CXCL10/ADORA2A/ABCA1/NPR3/PRKCA/PTGFR/PDE4D/CXCL11/EDN1/PTGER2/AKAP12/PTHLH/CXCL9/ADM2/MC1R/ADCY7/RGS2/LPAR1/GNA13/ADCY9/ADCY3/GNA12/ARRDC3/ADORA1/RAMP1/MRAP2/GPR161/MIR1-2/IAPP/ADRB3/GRM2/LGR4/ADRA2A/WASF2/GNG2	37
BP	GO:0007040	lysosome organization	13/2306	61/18670	0.03319	0.1456	0.112	ABCA1/GNPTAB/PPT1/VPS35/ARF1/TMEM175/HOOK3/CLN8/TMEM106B/CHMP5/AKTIP/P2RX7/TMEM165	13
BP	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	13/2306	61/18670	0.03319	0.1456	0.112	BIRC3/TNFAIP3/BIRC2/CYLD/CLIP3/TRAF2/TNF/TAX1BP1/RBCK1/GAS6/PYDC2/ZNF675/PELI3	13
BP	GO:0030521	androgen receptor signaling pathway	13/2306	61/18670	0.03319	0.1456	0.112	PPARGC1A/DAB2/DAXX/DNAJA1/RNF14/FHL2/SIRT1/NKX3-1/DDX5/RNF4/ARID1A/NCOR2/CDK7	13
BP	GO:0080171	lytic vacuole organization	13/2306	61/18670	0.03319	0.1456	0.112	ABCA1/GNPTAB/PPT1/VPS35/ARF1/TMEM175/HOOK3/CLN8/TMEM106B/CHMP5/AKTIP/P2RX7/TMEM165	13
BP	GO:0032365	intracellular lipid transport	10/2306	43/18670	0.03369	0.1471	0.1132	ABCA1/ACACB/FABP3/CPT1A/ACACA/PLEKHA3/SLC25A20/PRKAB2/SCP2/MID1IP1	10
BP	GO:0043616	keratinocyte proliferation	10/2306	43/18670	0.03369	0.1471	0.1132	EREG/ZFP36/SNAI2/YAP1/HAS2/VDR/KRT2/TP63/FGF10/FERMT1	10
BP	GO:0070296	sarcoplasmic reticulum calcium ion transport	10/2306	43/18670	0.03369	0.1471	0.1132	GSTO1/CALM1/PDE4D/CAMK2D/CCL3/CALM2/ATP2A2/MIR1-2/SRI/CASQ1	10
BP	GO:0002011	morphogenesis of an epithelial sheet	12/2306	55/18670	0.03373	0.1471	0.1132	PDPN/CD44/MSX2/HBEGF/PHLDB2/WNT5A/FLRT3/TOR1A/DVL1/LIN7C/DVL2/COL5A1	12
BP	GO:0032781	positive regulation of ATPase activity	12/2306	55/18670	0.03373	0.1471	0.1132	PLSCR1/DNAJA1/DNAJC19/RAB4A/DNAJC15/RAB3A/RGN/PFN2/NCAPH/DYNLL1/SETMAR/FGF10	12
BP	GO:0042304	regulation of fatty acid biosynthetic process	12/2306	55/18670	0.03373	0.1471	0.1132	PTGS2/IL1B/INSIG2/GIP/ELOVL5/TRIB3/ADIPOR2/ABCD1/SIRT1/RGN/PRKAB2/MID1IP1	12
BP	GO:0043030	regulation of macrophage activation	12/2306	55/18670	0.03373	0.1471	0.1132	ZC3H12A/IL6/SLC7A2/IL33/IL4R/CCL3/THBS1/WNT5A/MYO18A/HAVCR2/CEBPA/PJA2	12
BP	GO:0043551	regulation of phosphatidylinositol 3-kinase activity	12/2306	55/18670	0.03373	0.1471	0.1132	KIT/FGF2/PDGFRB/SOCS1/SOCS3/IRS1/KLF4/PIK3R2/PIK3R3/TNFAIP8L3/SOCS2/WDR91	12
BP	GO:0003018	vascular process in circulatory system	30/2306	173/18670	0.03387	0.1476	0.1136	SOD2/ICAM1/PTGS2/ITGA1/BDKRB2/ADORA2A/C2CD4B/DDAH1/VEGFA/ROCK1/SLIT2/BMPR2/GCH1/OXTR/EDN1/AKAP12/F2R/RGS2/BBS2/ADORA1/PTPRM/DOCK4/UTS2R/ADRB3/CPS1/ROCK2/HBB/NPPA/SERPINF2/ADRA2A	30
BP	GO:0097061	dendritic spine organization	16/2306	80/18670	0.0339	0.1476	0.1136	SIPA1L1/DBN1/CAPRIN1/EEF2K/FYN/ITPKA/CDK5/VPS35/BHLHB9/ARF1/PDLIM5/DLG4/ACTR2/CDC42/DVL1/NGEF	16
BP	GO:0001913	T cell mediated cytotoxicity	11/2306	49/18670	0.03394	0.1476	0.1136	IL7R/HLA-E/IL12A/HLA-F/FADD/HLA-A/MICB/HLA-G/P2RX7/HLA-B/HLA-H	11
BP	GO:0032757	positive regulation of interleukin-8 production	11/2306	49/18670	0.03394	0.1476	0.1136	IL1B/CD58/DDX58/FADD/F2R/PRG3/WNT5A/TNF/TLR3/SERPINE1/BCL10	11
BP	GO:0010758	regulation of macrophage chemotaxis	7/2306	26/18670	0.03423	0.148	0.1139	CCL5/CSF1/CMKLR1/THBS1/AKIRIN1/SLAMF8/CYP19A1	7
BP	GO:0032967	positive regulation of collagen biosynthetic process	7/2306	26/18670	0.03423	0.148	0.1139	BMP4/PDGFRB/MYB/F2R/ITGA2/ENG/SERPINF2	7
BP	GO:0034114	regulation of heterotypic cell-cell adhesion	7/2306	26/18670	0.03423	0.148	0.1139	IL1B/CD44/MYADM/KLF4/MBP/FLOT1/TNF	7
BP	GO:0043090	amino acid import	7/2306	26/18670	0.03423	0.148	0.1139	SLC7A2/SLC7A11/ARL6IP5/SLC3A2/RGS2/RGS4/CLN8	7
BP	GO:0060037	pharyngeal system development	7/2306	26/18670	0.03423	0.148	0.1139	SIX1/BMP4/BMPR2/TGFB2/SIX4/NKX3-1/GATA3	7
BP	GO:0060544	regulation of necroptotic process	7/2306	26/18670	0.03423	0.148	0.1139	BIRC3/BIRC2/CFLAR/FADD/CYLD/RBCK1/MIR214	7
BP	GO:0060706	cell differentiation involved in embryonic placenta development	7/2306	26/18670	0.03423	0.148	0.1139	LIF/SOCS3/NR2F2/STK4/ASCL2/KRT19/PRDM1	7
BP	GO:1903579	negative regulation of ATP metabolic process	7/2306	26/18670	0.03423	0.148	0.1139	PID1/PPARGC1A/PPIF/PDE12/DNAJC15/STAT3/SIRT6	7
BP	GO:0002697	regulation of immune effector process	70/2306	458/18670	0.03425	0.148	0.1139	CXCL6/NFKBIZ/BIRC3/ZC3H12A/TNFAIP3/IL6/IL1B/RIPK2/IL33/BIRC2/IL7R/TNFRSF14/RSAD2/C3/TNFRSF1B/STAT1/DDX60/TRAF3/HLA-E/IL12A/IL18R1/MYB/IL4R/IFIT1/APOBEC3G/TSPAN6/HLA-F/CD40/IRAK3/DDX58/TRAF3IP2/SNX4/FADD/ITCH/HLA-A/IL15/EXOSC6/EIF2AK4/DHX58/TGFB2/CLCF1/STAT6/PARP9/WNT5A/TRAF2/MYO18A/CFB/MICB/HAVCR2/TNF/SLAMF8/APPL2/HERC5/STXBP1/TLR3/TRIM6/GATA3/HLA-G/NCR1/APOBEC3F/BCL10/DUSP10/VAMP7/NPPA/TICAM1/TRIM38/P2RX7/HLA-B/SASH3/HLA-H	70
BP	GO:1901987	regulation of cell cycle phase transition	73/2306	480/18670	0.03435	0.1483	0.1141	BID/PSME2/CCL2/ID2/PSMA6/CDK6/PSMB10/FHL1/PSMB8/PSMB7/PSME1/PLK2/PSMB9/RPA2/PKD2/CCND1/KLF4/CDC16/PSMA3/CDC25A/SMARCD3/PRMT1/RDX/ZFP36L2/MAD1L1/CDC14B/GJC2/ERCC2/PPP1R9B/DCTN1/HECW2/CSNK1E/CARM1/PSMA1/CEP290/CEP250/PSMB2/CDKN2C/OFD1/NSMCE2/MIR19B2/UBE2E1/BTG2/PSMB3/CDKN1C/MIR137/ARID3A/CEP78/DYNLL1/CNOT8/UBD/NEK6/PSMA8/ZNF830/CDK2AP2/MIR214/CTDSP2/ZFYVE19/CDKN1A/FGF10/PSME4/TFDP1/PSMB5/DCTN3/CDC23/CEP63/MEPCE/PSMG2/TAOK1/UIMC1/FOXO4/PSMF1/NPM2	73
BP	GO:0032507	maintenance of protein location in cell	15/2306	74/18670	0.03517	0.1516	0.1166	DBN1/HK2/ANK3/EPB41L3/FLNB/BCL3/CDK5/TXN/GSN/TOPORS/SP100/ARL2BP/TLN1/RER1/MORC3	15
BP	GO:0032677	regulation of interleukin-8 production	15/2306	74/18670	0.03517	0.1516	0.1166	IL1B/CD58/DDX58/KLF4/FADD/F2R/PRG3/BCL3/WNT5A/ANXA4/TNF/TLR3/SERPINE1/BCL10/MAPKBP1	15
BP	GO:0043507	positive regulation of JUN kinase activity	15/2306	74/18670	0.03517	0.1516	0.1166	RIPK2/ERN1/DAXX/PAK1/EDN1/FZD8/WNT5A/TRAF2/ARHGEF5/TNF/MAP3K2/MLKL/FZD4/DVL2/TAOK1	15
BP	GO:0007519	skeletal muscle tissue development	28/2306	160/18670	0.03547	0.1527	0.1175	MAFF/MSC/PITX1/SIX1/CFLAR/POPDC2/SAP30/NR2F2/MYOM1/ARNTL/SRPK3/HOXD9/FLNB/FLOT1/MEOX2/SIX4/MEF2C/AKIRIN1/CDK5/BTG2/DDX5/BIN3/MIR1-2/PPP3CA/ASB2/CASQ1/DNER/VAMP5	28
BP	GO:0030203	glycosaminoglycan metabolic process	28/2306	160/18670	0.03547	0.1527	0.1175	IL1B/ST3GAL1/NFKB1/FGF2/PDGFRB/GPC4/B4GALT3/CD44/VCAN/CHST7/HSPG2/IL15/PIM1/GLB1/CLTC/SDC2/CSGALNACT1/HAS2/CSGALNACT2/GALNT5/ITIH1/HAS1/HAS3/EXT1/ST3GAL3/SDC4/HS2ST1/ST3GAL4	28
BP	GO:0070372	regulation of ERK1 and ERK2 cascade	48/2306	300/18670	0.03572	0.1536	0.1182	CCL20/BMP2/ICAM1/CCL5/TNIP1/IL1B/LIF/RIPK2/CCL2/CCL8/CCL7/KIT/FGF2/CNKSR3/PRKCA/DUSP6/CFLAR/BMP4/PDGFRB/CCL3L3/CD44/IL26/KLF4/CCL3/GBP1/BMPER/AKAP12/PDGFD/SIRPA/F2R/CCL1/SPRY1/ERRFI1/DUSP3/TNFAIP8L3/HAVCR2/TNF/PDGFC/NPTN/ABL1/DUSP10/GAS6/PTPN11/FGF10/ROS1/SERPINF2/CRKL/GLIPR2	48
BP	GO:0002690	positive regulation of leukocyte chemotaxis	17/2306	87/18670	0.036	0.1546	0.119	CCL5/IL6/CXCL10/CSF1/CCL7/VEGFA/IL12A/CMKLR1/CCL3/THBS1/EDN1/CCL1/AKIRIN1/WNT5A/PGF/SERPINE1/GAS6	17
BP	GO:0051781	positive regulation of cell division	17/2306	87/18670	0.036	0.1546	0.119	IL1B/IL1A/FGF2/VEGFA/EREG/LBH/TGFA/CDC14B/PDGFD/TGFB2/NKX3-1/PGF/FGF5/PDGFC/PKP4/PKN2/CDC42	17
BP	GO:0120034	positive regulation of plasma membrane bounded cell projection assembly	19/2306	100/18670	0.03606	0.1547	0.1191	FSCN1/KIT/FNBP1L/AUTS2/CDC42EP1/CDC42EP3/CCDC88A/DPYSL3/AKIRIN1/ARPC2/EPS8/DYNLL1/PLEK2/MARK4/RALA/MNS1/CDC42/P2RX7/WASF2	19
BP	GO:0006625	protein targeting to peroxisome	14/2306	68/18670	0.03636	0.1557	0.1198	ACOX2/IDH1/NUDT7/CROT/AMACR/DECR2/LONP2/PEX1/ACOT8/PECR/UBB/SCP2/PEX26/USP9X	14
BP	GO:0072662	protein localization to peroxisome	14/2306	68/18670	0.03636	0.1557	0.1198	ACOX2/IDH1/NUDT7/CROT/AMACR/DECR2/LONP2/PEX1/ACOT8/PECR/UBB/SCP2/PEX26/USP9X	14
BP	GO:0072663	establishment of protein localization to peroxisome	14/2306	68/18670	0.03636	0.1557	0.1198	ACOX2/IDH1/NUDT7/CROT/AMACR/DECR2/LONP2/PEX1/ACOT8/PECR/UBB/SCP2/PEX26/USP9X	14
BP	GO:0034620	cellular response to unfolded protein	25/2306	140/18670	0.03638	0.1557	0.1198	CCL2/ERN1/DAXX/PPP1R15A/TBL2/FICD/HERPUD1/DNAJB9/CCND1/LMNA/HDGF/WIPI1/DCTN1/SERP2/DNAJC3/OPTN/HYOU1/ASNS/SSR1/CTDSP2/RNF121/TSPYL2/TLN1/TMEM33/BFAR	25
BP	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	8/2306	32/18670	0.037	0.1557	0.1198	GSTO1/CALM1/PDE4D/CAMK2D/CALM2/MIR1-2/SRI/CASQ1	8
BP	GO:0045987	positive regulation of smooth muscle contraction	8/2306	32/18670	0.037	0.1557	0.1198	PTGS2/KIT/OXTR/ADA/EDN1/F2R/ITGA2/ABAT	8
BP	GO:0050779	RNA destabilization	8/2306	32/18670	0.037	0.1557	0.1198	ZC3H12A/TNFRSF1B/ROCK1/MOV10/FTO/ZFP36/ZFP36L2/ROCK2	8
BP	GO:0060317	cardiac epithelial to mesenchymal transition	8/2306	32/18670	0.037	0.1557	0.1198	BMP2/MSX2/TGFB2/SPRY1/SNAI2/HAS2/RTN4/ENG	8
BP	GO:1900745	positive regulation of p38MAPK cascade	8/2306	32/18670	0.037	0.1557	0.1198	BMP2/ZC3H12A/IL1B/VEGFA/PRMT1/GADD45G/PJA2/GDF6	8
BP	GO:0045017	glycerolipid biosynthetic process	41/2306	251/18670	0.03701	0.1557	0.1198	GK/PLD1/LPIN1/FGF2/PIK3CD/GPD1L/PLCE1/PLSCR1/C3/PLA2G4A/RAB38/FABP3/PISD/PIGV/PIK3R2/PTPN13/PIK3R3/RAB4A/PLEKHA3/CPNE3/PLA2G12A/RGN/ARF1/ARF3/ABHD5/ABHD3/GPAM/MPPE1/PIGK/PIGS/CHKB/PIP4K2A/FAR1/SIK1/PI4K2B/SH3YL1/SBF1/PLEKHA4/CAPN2/LCLAT1/STARD7	41
BP	GO:0043524	negative regulation of neuron apoptotic process	26/2306	147/18670	0.03703	0.1557	0.1198	SOD2/CCL2/ADORA2A/PPARGC1A/CEBPB/SIX1/ROCK1/SET/FYN/NRBP2/PPT1/HIPK2/F2R/CLCF1/GDF5/SIX4/AXL/MEF2C/BHLHB9/BCL2L1/BTG2/HYOU1/STXBP1/OXR1/EN2/ADAM8	26
BP	GO:1901657	glycosyl compound metabolic process	26/2306	147/18670	0.03703	0.1557	0.1198	AKR1B1/RAB23/PRPS1/TYMP/PRPS1L1/APOBEC3G/AMPD3/NUDT18/ADA/NAGA/GLA/APOBEC3H/NT5C2/NME5/CBR4/IMPDH2/GAMT/CDADC1/GUK1/LCMT2/MTAP/PRTFDC1/APOBEC3F/TK2/DCK/GNMT	26
BP	GO:0000470	maturation of LSU-rRNA	6/2306	21/18670	0.0371	0.1557	0.1198	ZNHIT3/RPL7/MRPL1/BOP1/URB1/FTSJ3	6
BP	GO:0001779	natural killer cell differentiation	6/2306	21/18670	0.0371	0.1557	0.1198	ID2/PIK3CD/IL15/AXL/PRDM1/GAS6	6
BP	GO:0003094	glomerular filtration	6/2306	21/18670	0.0371	0.1557	0.1198	SULF2/MYO1E/F2R/ADORA1/SULF1/GAS6	6
BP	GO:0003177	pulmonary valve development	6/2306	21/18670	0.0371	0.1557	0.1198	TNFRSF1B/BMP4/SLIT2/BMPR2/TGFB2/ROBO1	6
BP	GO:0010829	negative regulation of glucose transmembrane transport	6/2306	21/18670	0.0371	0.1557	0.1198	PID1/IL1B/ENPP1/TNF/APPL2/SIRT6	6
BP	GO:0035743	CD4-positive, alpha-beta T cell cytokine production	6/2306	21/18670	0.0371	0.1557	0.1198	IL6/IL1B/RSAD2/IL12A/IL18R1/GATA3	6
BP	GO:0048245	eosinophil chemotaxis	6/2306	21/18670	0.0371	0.1557	0.1198	CCL5/CCL2/CCL8/CCL7/CCL3/CCL1	6
BP	GO:0061003	positive regulation of dendritic spine morphogenesis	6/2306	21/18670	0.0371	0.1557	0.1198	DBN1/CAPRIN1/EEF2K/ITPKA/BHLHB9/ACTR2	6
BP	GO:1903055	positive regulation of extracellular matrix organization	6/2306	21/18670	0.0371	0.1557	0.1198	IL6/FSCN1/PDPN/CFLAR/PHLDB1/PHLDB2	6
BP	GO:1904469	positive regulation of tumor necrosis factor secretion	6/2306	21/18670	0.0371	0.1557	0.1198	IFIH1/IFNGR1/DDX58/AKAP12/WNT5A/HAVCR2	6
BP	GO:2000737	negative regulation of stem cell differentiation	6/2306	21/18670	0.0371	0.1557	0.1198	LBH/ZFP36L2/YAP1/HES5/TRIM6/STAT3	6
BP	GO:0006006	glucose metabolic process	35/2306	209/18670	0.03721	0.1557	0.1198	OAS1/PPARGC1A/C1QTNF1/FOXO1/HK2/PPP1R3F/ACACB/GALM/ENO2/ADPGK/COX11/IRS1/NFE2L1/PGM2L1/DYRK2/PHLDA2/ENPP1/PMAIP1/CPT1A/KAT2B/NISCH/LRP5/SIRT1/RGN/SESN2/TNF/PDHB/ALDH5A1/DUSP12/PDK3/SLC35B4/SIK1/IGF1/GNMT/ALDOC	35
BP	GO:0008154	actin polymerization or depolymerization	35/2306	209/18670	0.03721	0.1557	0.1198	ICAM1/ARPC1A/DBN1/CDC42EP1/ARHGAP18/LIMA1/ACTR3/CDC42EP3/SLIT2/MYADM/ARHGAP28/FMN2/RDX/DSTN/PLEKHH2/TTC17/ARPC2/ENAH/CAPZA2/ARF6/MICAL3/ARF1/PFN2/EPS8/GSN/CAP2/DIAPH1/PRKCD/GMFB/MIR214/PDXP/ACTR2/TMOD2/PLEKHG2/MAGEL2	35
BP	GO:0051216	cartilage development	35/2306	209/18670	0.03721	0.1557	0.1198	BMP2/PITX1/FGF2/BMP4/COL1A1/CD44/BMPR2/HOXA11/MSX2/SCARA3/SULF2/EDN1/PTHLH/CYTL1/SOX5/ITGB8/CSGALNACT1/THRA/SNAI2/BBS2/WNT5B/GDF5/CARM1/MEF2C/WNT5A/SULF1/COL6A3/HES5/HOXD3/OSR2/SERPINH1/RSPO2/GDF6/OSR1/NFIB	35
BP	GO:0048857	neural nucleus development	13/2306	62/18670	0.03742	0.1557	0.1198	BASP1/ALDH1A3/CALM1/GLUD1/MBP/SYPL2/GNB4/ACTB/YWHAH/DYNLL1/CALM2/CDC42/NFIB	13
BP	GO:0003093	regulation of glomerular filtration	4/2306	11/18670	0.03744	0.1557	0.1198	CYBA/F2R/ADORA1/GAS6	4
BP	GO:0009151	purine deoxyribonucleotide metabolic process	4/2306	11/18670	0.03744	0.1557	0.1198	NUDT18/ADA/NUDT1/GUK1	4
BP	GO:0019042	viral latency	4/2306	11/18670	0.03744	0.1557	0.1198	IRF7/PPIA/XRCC4/NUCKS1	4
BP	GO:0019852	L-ascorbic acid metabolic process	4/2306	11/18670	0.03744	0.1557	0.1198	SLC2A1/GSTO1/CYB5A/RGN	4
BP	GO:0031652	positive regulation of heat generation	4/2306	11/18670	0.03744	0.1557	0.1198	PTGS2/IL1B/ABAT/TNF	4
BP	GO:0033629	negative regulation of cell adhesion mediated by integrin	4/2306	11/18670	0.03744	0.1557	0.1198	SNAI2/SERPINE1/PDE3B/PTPN11	4
BP	GO:0044793	negative regulation by host of viral process	4/2306	11/18670	0.03744	0.1557	0.1198	ZC3H12A/CCL8/EIF2AK4/PTX3	4
BP	GO:0048548	regulation of pinocytosis	4/2306	11/18670	0.03744	0.1557	0.1198	PPT1/AXL/APPL2/ACTN4	4
BP	GO:0051574	positive regulation of histone H3-K9 methylation	4/2306	11/18670	0.03744	0.1557	0.1198	JARID2/MYB/LMNA/SIRT1	4
BP	GO:0060272	embryonic skeletal joint morphogenesis	4/2306	11/18670	0.03744	0.1557	0.1198	BMP4/HOXA11/OSR2/OSR1	4
BP	GO:0060992	response to fungicide	4/2306	11/18670	0.03744	0.1557	0.1198	KLF2/KLF4/SRD5A1/BCL2L1	4
BP	GO:0072110	glomerular mesangial cell proliferation	4/2306	11/18670	0.03744	0.1557	0.1198	CFLAR/BMP4/PDGFRB/PDGFD	4
BP	GO:0072537	fibroblast activation	4/2306	11/18670	0.03744	0.1557	0.1198	PDGFRB/MYB/AKAP12/CYGB	4
BP	GO:0072683	T cell extravasation	4/2306	11/18670	0.03744	0.1557	0.1198	ICAM1/CCL2/FADD/CRKL	4
BP	GO:0090073	positive regulation of protein homodimerization activity	4/2306	11/18670	0.03744	0.1557	0.1198	MEF2C/TRAF2/ARF6/CRBN	4
BP	GO:1900003	regulation of serine-type endopeptidase activity	4/2306	11/18670	0.03744	0.1557	0.1198	ANXA8/MIR19B2/SPINK6/SPINK1	4
BP	GO:1901077	regulation of relaxation of muscle	4/2306	11/18670	0.03744	0.1557	0.1198	PDE4D/CAMK2D/PDE4B/SRI	4
BP	GO:1902571	regulation of serine-type peptidase activity	4/2306	11/18670	0.03744	0.1557	0.1198	ANXA8/MIR19B2/SPINK6/SPINK1	4
BP	GO:1904396	regulation of neuromuscular junction development	4/2306	11/18670	0.03744	0.1557	0.1198	SIX1/DCTN1/SIX4/CRKL	4
BP	GO:0051341	regulation of oxidoreductase activity	20/2306	107/18670	0.03748	0.1558	0.1198	IL1B/NFKB1/NPR3/DDAH1/CALM1/CYBA/GCH1/GLA/EDN1/CYP27B1/COX17/NOSTRIN/CYGB/VDR/RGN/TNF/SLAMF8/CNR2/DDAH2/ABL1	20
BP	GO:0070167	regulation of biomineral tissue development	18/2306	94/18670	0.03785	0.1569	0.1207	BMP2/CEBPB/ISG15/ROCK1/BMP4/BMPR2/CCL3/CYP27B1/ENPP1/MEF2C/SRGN/BGLAP/BMP2K/OSR2/ROCK2/GAS6/OSR1/P2RX7	18
BP	GO:0032635	interleukin-6 production	28/2306	161/18670	0.03806	0.1569	0.1207	ZC3H12A/TNFAIP3/IL6/IL1B/RIPK2/IL33/IFIH1/CEBPB/EREG/KLF2/IRAK3/DDX58/CYBA/MAPK13/MBP/SIRPA/F2R/WNT5A/HAVCR2/TNF/TLR3/BCL10/GAS6/PTPN11/TICAM1/STAT3/P2RX7/CAPN2	28
BP	GO:0035967	cellular response to topologically incorrect protein	28/2306	161/18670	0.03806	0.1569	0.1207	CCL2/ERN1/DAXX/PPP1R15A/TBL2/FICD/HERPUD1/DNAJB9/CCND1/LMNA/HDGF/WIPI1/DCTN1/SERP2/DNAJC3/RNF5/OPTN/HYOU1/ASNS/SSR1/CTDSP2/TOR1A/RNF121/TSPYL2/TLN1/RNF126/TMEM33/BFAR	28
BP	GO:0050879	multicellular organismal movement	12/2306	56/18670	0.03827	0.1569	0.1207	GSTO1/DMPK/HIPK2/MAP1A/SYNM/STAC/VPS35/CHRNB1/CLN8/ATP2A2/ATP8A2/CASQ1	12
BP	GO:0050881	musculoskeletal movement	12/2306	56/18670	0.03827	0.1569	0.1207	GSTO1/DMPK/HIPK2/MAP1A/SYNM/STAC/VPS35/CHRNB1/CLN8/ATP2A2/ATP8A2/CASQ1	12
BP	GO:1903202	negative regulation of oxidative stress-induced cell death	12/2306	56/18670	0.03827	0.1569	0.1207	SOD2/GPR37L1/HSPB1/NCOA7/SLC7A11/FZD1/FYN/NME5/SIRT1/ATG7/TXN/OXR1	12
BP	GO:0003298	physiological muscle hypertrophy	9/2306	38/18670	0.03843	0.1569	0.1207	PAK1/EDN1/RGS2/MIR19B2/RGS4/PDLIM5/NPPA/MIR199A2/IGF1	9
BP	GO:0003301	physiological cardiac muscle hypertrophy	9/2306	38/18670	0.03843	0.1569	0.1207	PAK1/EDN1/RGS2/MIR19B2/RGS4/PDLIM5/NPPA/MIR199A2/IGF1	9
BP	GO:0006084	acetyl-CoA metabolic process	9/2306	38/18670	0.03843	0.1569	0.1207	KYNU/ACACB/NUDT7/ACAT1/ACACA/AADAT/PPCS/PDHB/PDK3	9
BP	GO:0009225	nucleotide-sugar metabolic process	9/2306	38/18670	0.03843	0.1569	0.1207	GFPT2/UGP2/NAGK/GMDS/GMPPB/CSGALNACT1/PGM3/MGAT1/GUK1	9
BP	GO:0046329	negative regulation of JNK cascade	9/2306	38/18670	0.03843	0.1569	0.1207	DNAJA1/ITCH/CYLD/SIRPA/DUSP3/DUSP10/PER1/SH3RF2/ZNF675	9
BP	GO:0046825	regulation of protein export from nucleus	9/2306	38/18670	0.03843	0.1569	0.1207	IL1B/TCF7L2/CDK5/TXN/SP100/IWS1/CTDSPL2/GAS6/PTPN11	9
BP	GO:0048246	macrophage chemotaxis	9/2306	38/18670	0.03843	0.1569	0.1207	CCL5/CCL2/CSF1/CMKLR1/CCL3/THBS1/AKIRIN1/SLAMF8/CYP19A1	9
BP	GO:0051590	positive regulation of neurotransmitter transport	9/2306	38/18670	0.03843	0.1569	0.1207	ADORA2A/SNX4/RAB3GAP1/CDK5/STXBP1/SYT1/VAMP7/NPPA/P2RX7	9
BP	GO:0060416	response to growth hormone	9/2306	38/18670	0.03843	0.1569	0.1207	SRD5A1/PXN/GHR/STAT6/GDF15/ASS1/SOCS2/CPS1/STAT3	9
BP	GO:0061049	cell growth involved in cardiac muscle cell development	9/2306	38/18670	0.03843	0.1569	0.1207	PAK1/EDN1/RGS2/MIR19B2/RGS4/PDLIM5/NPPA/MIR199A2/IGF1	9
BP	GO:1903523	negative regulation of blood circulation	9/2306	38/18670	0.03843	0.1569	0.1207	ZC3H12A/PDE4D/BMPR2/F2R/ADORA1/ATP2A2/DOCK4/PDE5A/SRI	9
BP	GO:0043542	endothelial cell migration	44/2306	273/18670	0.03855	0.1569	0.1207	ZC3H12A/PTGS2/HSPB1/FGF2/PRKCA/VEGFA/PLK2/BMP4/RAB13/CD40/SLIT2/RHOJ/ETS1/NR2F2/BMPR2/KLF4/THBS1/EDN1/BMPER/PXN/CARD10/RHOB/PIK3R3/STARD13/MEOX2/AMOTL1/ROBO1/MEF2C/SIRT1/MIR19B2/WNT5A/MIR137/SPARC/PTPRM/PLXND1/SP100/GATA3/ABL1/ROCK2/LGALS8/PPARG/MYH9/MIR199A2/ATOH8	44
BP	GO:0034765	regulation of ion transmembrane transport	73/2306	483/18670	0.03869	0.1569	0.1207	BDKRB1/CXCL10/CCL2/PPARGC1A/FHL1/CNKSR3/GPD1L/DAPK1/CTSS/GSTO1/RRAD/PPIF/FYN/CALM1/PDE4D/CAMK2D/CLIC6/ARL6IP5/PKD2/CXCL11/ANK3/CYBA/THBS1/UBASH3B/CXCL9/COX17/THADA/TRPC1/F2R/GJC2/CLIC3/CLCNKA/RGS2/GRIA3/HECW2/MMP9/HCN4/MEF2C/GEM/NOX5/STAC/RGS4/KCNB1/KCND1/TPCN1/RGN/CRBN/ARF1/SLC30A1/CACNA1F/CACNA1B/YWHAH/CALM2/ACTN4/MIR1-2/DLG4/STIM1/FKBP1A/DIAPH1/SNTA1/ABL1/PDE4B/KCND3/NPPA/KCNK17/CNIH2/OSR1/SRI/P2RX7/CASQ1/NEDD4/KCNB2/ADRA2A	73
BP	GO:0045446	endothelial cell differentiation	21/2306	114/18670	0.03872	0.1569	0.1207	ICAM1/IL1B/S1PR3/CLDN1/PDPN/VEGFA/ROCK1/BMP4/PDE4D/NR2F2/BMPR2/MYADM/EDF1/RDX/FOXJ2/TNF/MIR1-2/ROCK2/ENG/TJP1/ATOH8	21
BP	GO:0002739	regulation of cytokine secretion involved in immune response	5/2306	16/18670	0.0388	0.1569	0.1207	TNFRSF14/TNFRSF1B/WNT5A/TNF/TRIM6	5
BP	GO:0030033	microvillus assembly	5/2306	16/18670	0.0388	0.1569	0.1207	PLD1/FSCN1/ATP8B1/RDX/PODXL	5
BP	GO:0035372	protein localization to microtubule	5/2306	16/18670	0.0388	0.1569	0.1207	MID1/MAP1A/DIAPH1/MAPRE2/DVL1	5
BP	GO:0042447	hormone catabolic process	5/2306	16/18670	0.0388	0.1569	0.1207	DIO2/SRD5A1/YWHAH/HSD17B6/CYP19A1	5
BP	GO:0043174	nucleoside salvage	5/2306	16/18670	0.0388	0.1569	0.1207	TYMP/MTAP/PRTFDC1/TK2/DCK	5
BP	GO:0044827	modulation by host of viral genome replication	5/2306	16/18670	0.0388	0.1569	0.1207	ZC3H12A/CCL8/FBXL2/EIF2AK4/NUCKS1	5
BP	GO:0044849	estrous cycle	5/2306	16/18670	0.0388	0.1569	0.1207	ETS1/OXTR/HAS2/HAS1/NCOR2	5
BP	GO:0046325	negative regulation of glucose import	5/2306	16/18670	0.0388	0.1569	0.1207	PID1/ENPP1/TNF/APPL2/SIRT6	5
BP	GO:0048820	hair follicle maturation	5/2306	16/18670	0.0388	0.1569	0.1207	MSX2/ERCC2/TGFB2/WNT5A/FERMT1	5
BP	GO:0050711	negative regulation of interleukin-1 secretion	5/2306	16/18670	0.0388	0.1569	0.1207	ZC3H12A/TNFAIP3/SERPINB1/GAS6/PYDC2	5
BP	GO:0070293	renal absorption	5/2306	16/18670	0.0388	0.1569	0.1207	KLHL3/HAS2/GSN/HBB/GAS6	5
BP	GO:0071380	cellular response to prostaglandin E stimulus	5/2306	16/18670	0.0388	0.1569	0.1207	PTGER2/ACACA/AKAP8/PPARG/GNG2	5
BP	GO:0071732	cellular response to nitric oxide	5/2306	16/18670	0.0388	0.1569	0.1207	MMP3/FOXO1/CFLAR/TRAF2/MTR	5
BP	GO:0072176	nephric duct development	5/2306	16/18670	0.0388	0.1569	0.1207	AHI1/BMP4/PKD2/GATA3/OSR1	5
BP	GO:0072488	ammonium transmembrane transport	5/2306	16/18670	0.0388	0.1569	0.1207	SLC22A1/SLC22A4/SLC12A2/SLC25A20/RHD	5
BP	GO:0090335	regulation of brown fat cell differentiation	5/2306	16/18670	0.0388	0.1569	0.1207	PTGS2/FTO/FNDC5/SIRT1/DUSP10	5
BP	GO:0097067	cellular response to thyroid hormone stimulus	5/2306	16/18670	0.0388	0.1569	0.1207	PPARGC1A/KIT/SIX1/CTSS/RDX	5
BP	GO:1905153	regulation of membrane invagination	5/2306	16/18670	0.0388	0.1569	0.1207	C3/ITGA2/APPL2/PPARG/RAB31	5
BP	GO:0042398	cellular modified amino acid biosynthetic process	11/2306	50/18670	0.03883	0.1569	0.1207	PLSCR1/SLC7A11/GCH1/PLOD2/CHAC2/GAMT/HAGH/ALDH7A1/CNDP2/MGST2/ACADM	11
BP	GO:0046854	phosphatidylinositol phosphorylation	11/2306	50/18670	0.03883	0.1569	0.1207	PIK3CD/SOCS1/SOCS3/PIK3R2/PIK3R3/IMPA2/EFR3A/SOCS2/PIP4K2A/INPP1/PI4K2B	11
BP	GO:0097035	regulation of membrane lipid distribution	11/2306	50/18670	0.03883	0.1569	0.1207	KCNN4/ABCA1/ATP8B1/PLSCR1/ABCC1/TLCD1/ATP8A2/PRKCD/PLSCR2/P2RX7/TMEM30B	11
BP	GO:0010463	mesenchymal cell proliferation	10/2306	44/18670	0.03895	0.1569	0.1207	BMP2/SIX1/STAT1/VEGFA/BMP4/LMNA/LRP5/WNT5A/OSR1/NFIB	10
BP	GO:0014002	astrocyte development	10/2306	44/18670	0.03895	0.1569	0.1207	IL6/IL1B/ADORA2A/CDK6/IFNGR1/BACE2/ROR1/TNF/EIF2B5/TSPAN2	10
BP	GO:0034105	positive regulation of tissue remodeling	10/2306	44/18670	0.03895	0.1569	0.1207	PRKCA/ROCK1/IL15/TMEM64/VDR/PPP3CA/ROCK2/MIR214/MIR199A2/ADAM8	10
BP	GO:0045601	regulation of endothelial cell differentiation	10/2306	44/18670	0.03895	0.1569	0.1207	IL1B/S1PR3/VEGFA/ROCK1/BMP4/FOXJ2/TNF/MIR1-2/ROCK2/ATOH8	10
BP	GO:0061001	regulation of dendritic spine morphogenesis	10/2306	44/18670	0.03895	0.1569	0.1207	SIPA1L1/DBN1/CAPRIN1/EEF2K/ITPKA/CDK5/BHLHB9/PDLIM5/ACTR2/NGEF	10
BP	GO:0090382	phagosome maturation	10/2306	44/18670	0.03895	0.1569	0.1207	ATP6V1E2/ATP6V0B/RAB38/ATP6V0E2/RAB32/TMEM175/SLAMF8/P2RX7/RAB31/ATP6V1E1	10
BP	GO:0015914	phospholipid transport	15/2306	75/18670	0.03913	0.1574	0.1211	KCNN4/OSBPL10/ABCA1/PITPNC1/ATP8B1/ABCC1/PLEKHA3/TNFAIP8L3/OSBPL5/ATP8A2/PRKCD/SCP2/P2RX7/TMEM30B/STARD7	15
BP	GO:0150076	neuroinflammatory response	15/2306	75/18670	0.03913	0.1574	0.1211	NAMPT/PTGS2/IL6/IL1B/IL33/ADORA2A/MMP3/IFNGR1/BACE2/TNFRSF1B/CCL3/MMP9/TNF/TLR3/IGF1	15
BP	GO:0008286	insulin receptor signaling pathway	25/2306	141/18670	0.03922	0.1577	0.1213	PID1/IL1B/FOXO1/PTPRE/ATP6V1E2/PAK1/SOCS1/SOCS3/ATP6V0B/IRS1/GRB14/ATP6V0E2/PIK3R2/ENPP1/PIK3R3/SESN3/SIRT1/SOCS2/PRKCD/NUCKS1/AP3S1/PTPN11/NCOA5/ATP6V1E1/FOXO4	25
BP	GO:0046578	regulation of Ras protein signal transduction	39/2306	238/18670	0.03937	0.1581	0.1217	CYTH3/ABCA1/CSF1/SQSTM1/PSD4/PLCE1/AUTS2/ARHGEF10/PDGFRB/IQSEC1/NET1/RDX/STMN3/F2R/TGFB2/FGD4/SPRY1/LPAR1/FGD1/FLOT1/ROBO1/ARF6/ARHGEF5/EPS8/DGKI/TIAM2/ARHGEF17/ARHGEF12/MAPRE2/PLEKHG4/ABL1/ARHGDIB/FARP1/FGF10/IGF1/SHOC2/NGEF/PLEKHG2/CRKL	39
BP	GO:0010389	regulation of G2/M transition of mitotic cell cycle	33/2306	196/18670	0.03938	0.1581	0.1217	PSME2/PSMA6/PSMB10/FHL1/PSMB8/PSMB7/PSME1/PSMB9/CCND1/PSMA3/CDC25A/SMARCD3/DCTN1/CSNK1E/PSMA1/CEP290/CEP250/PSMB2/OFD1/MIR19B2/PSMB3/CEP78/DYNLL1/PSMA8/ZNF830/ZFYVE19/PSME4/PSMB5/DCTN3/CEP63/TAOK1/FOXO4/PSMF1	33
BP	GO:0031532	actin cytoskeleton reorganization	19/2306	101/18670	0.03946	0.1582	0.1217	PDLIM4/KIT/SIPA1L1/AUTS2/PAK1/NEDD9/MKLN1/CDK5/EPS8/GSN/PTK7/BRSK2/PLEK2/ABL1/RALA/ARHGDIB/FGF10/CDC42/MYH9	19
BP	GO:0032611	interleukin-1 beta production	19/2306	101/18670	0.03946	0.1582	0.1217	ZC3H12A/TNFAIP3/IL1B/S1PR3/RIPK2/HSPB1/ABCA1/PANX1/GBP5/CCL3/GSDMD/SIRPA/F2R/ERRFI1/WNT5A/SERPINB1/PYDC2/IGF1/P2RX7	19
BP	GO:0046474	glycerophospholipid biosynthetic process	36/2306	217/18670	0.03954	0.1585	0.1219	PLD1/LPIN1/FGF2/PIK3CD/GPD1L/PLSCR1/PLA2G4A/RAB38/FABP3/PISD/PIGV/PIK3R2/PTPN13/PIK3R3/RAB4A/PLEKHA3/CPNE3/PLA2G12A/ARF1/ARF3/ABHD5/ABHD3/GPAM/MPPE1/PIGK/PIGS/CHKB/PIP4K2A/FAR1/PI4K2B/SH3YL1/SBF1/PLEKHA4/CAPN2/LCLAT1/STARD7	36
BP	GO:0006767	water-soluble vitamin metabolic process	17/2306	88/18670	0.03968	0.1587	0.1221	KYNU/SLC2A1/MTHFD2L/GSTO1/MTHFD2/SLC19A3/ENPP1/PNPO/PSAT1/ABCC1/CYB5A/RGN/MTR/PDXP/SLC19A1/ALDH1L2/MMADHC	17
BP	GO:0034103	regulation of tissue remodeling	17/2306	88/18670	0.03968	0.1587	0.1221	TNFAIP3/IL6/PRKCA/ROCK1/IL15/UBASH3B/TMEM64/VDR/BGLAP/IAPP/PPP3CA/ROCK2/MIR214/TNFRSF11B/MIR199A2/P2RX7/ADAM8	17
BP	GO:1901888	regulation of cell junction assembly	17/2306	88/18670	0.03968	0.1587	0.1221	CLDN1/CORO1C/VEGFA/ROCK1/THBS1/SNAI2/DUSP3/FLOT1/PHLDB2/TNF/COL16A1/SDC4/ABL1/ROCK2/TJP1/NPHP1/CBFB	17
BP	GO:0046718	viral entry into host cell	22/2306	121/18670	0.03981	0.159	0.1223	ICAM1/CLDN1/ANPEP/XPR1/IFITM1/TNFRSF14/SLC20A2/TRIM25/EPS15/ITGB5/ITCH/ITGA2/PPIA/KPNA3/AXL/TRIM21/GSN/PTX3/ZNF639/GAS6/TRIM38/SNX3	22
BP	GO:0048675	axon extension	22/2306	121/18670	0.03981	0.159	0.1223	NTN1/ZFYVE27/DBN1/AUTS2/VEGFA/PAK1/VCL/SLIT2/BMPR2/RUFY3/SEMA4D/IFRD1/CDK5/WNT5A/GDI1/RTN4/ABL1/SEMA4F/CDH4/DVL1/RAPH1/USP9X	22
BP	GO:0070227	lymphocyte apoptotic process	14/2306	69/18670	0.04062	0.1622	0.1248	CCL5/IL7R/IDO1/BMP4/TRAF3IP2/FADD/SLC39A10/ADA/FNIP1/WNT5A/BCL10/P2RX7/ADAM8/CRKL	14
BP	GO:0002576	platelet degranulation	23/2306	128/18670	0.04074	0.1625	0.125	BRPF3/VEGFA/VCL/CALM1/VWF/THBS1/LHFPL2/TGFB2/PHACTR2/SRGN/SYTL4/SPARC/ACTN4/STXBP1/SERPINE1/GAS6/SERPINA4/SERPINA3/IGF1/APOOL/SERPINA1/SERPINF2/TLN1	23
BP	GO:0015718	monocarboxylic acid transport	28/2306	162/18670	0.04078	0.1625	0.125	IL1B/BDKRB2/SLC16A6/ATP8B1/SLC27A3/PLA2G4A/AQP9/PLIN2/ACACB/FABP3/RXRA/SLC16A5/THBS1/CROT/EDN1/CPT1A/ACACA/ABCD1/PLA2G12A/ABCC2/ABAT/SLC25A20/PRKAB2/PPARG/NMUR2/P2RX7/MID1IP1/SLC16A9	28
BP	GO:0031960	response to corticosteroid	28/2306	162/18670	0.04078	0.1625	0.125	ICAM1/PTGS2/IL6/CLDN1/FOXO1/CFLAR/COL1A1/SLIT2/CCND1/CYBA/ZFP36/EDN1/SRD5A1/GLB1/ZFP36L2/HNMT/SMYD3/ERRFI1/GJB2/ABCC2/TNF/BGLAP/ASS1/SPARC/PAPPA/CPS1/CDKN1A/ENG	28
BP	GO:0032526	response to retinoic acid	20/2306	108/18670	0.04086	0.1627	0.1252	PTGES/ABCA1/PDGFRB/MYB/COL1A1/RXRA/KLF4/GJB2/WNT5B/YAP1/IGF2R/WNT5A/TNC/MICB/PTK7/FZD4/PPARG/OSR1/FZD7/GDAP2	20
BP	GO:0045619	regulation of lymphocyte differentiation	29/2306	169/18670	0.04114	0.1637	0.1259	NFKBIZ/ZC3H12A/CD83/RIPK2/ID2/SH3RF1/IRF1/TNFSF9/IL7R/BMP4/IL12A/MYB/IL4R/SOCS1/IL15/CYLD/ADA/ZFP36L2/AXL/SLAMF8/GATA3/HLA-G/PRDM1/ABL1/DUSP10/GAS6/SASH3/ADAM8/CBFB	29
BP	GO:0002021	response to dietary excess	7/2306	27/18670	0.04145	0.1637	0.126	PPARGC1A/SGIP1/GDF15/APPL2/NMUR2/TBL1XR1/RMI1	7
BP	GO:0003148	outflow tract septum morphogenesis	7/2306	27/18670	0.04145	0.1637	0.126	BMP4/BMPR2/MSX2/TGFB2/GATA6/ROBO1/ENG	7
BP	GO:0006706	steroid catabolic process	7/2306	27/18670	0.04145	0.1637	0.126	SRD5A1/CYP27B1/CYP1A2/HSD3B7/YWHAH/HSD17B6/CYP19A1	7
BP	GO:0007176	regulation of epidermal growth factor-activated receptor activity	7/2306	27/18670	0.04145	0.1637	0.126	GPRC5A/EREG/TGFA/ERRFI1/ADORA1/CBLB/ADRA2A	7
BP	GO:0010714	positive regulation of collagen metabolic process	7/2306	27/18670	0.04145	0.1637	0.126	BMP4/PDGFRB/MYB/F2R/ITGA2/ENG/SERPINF2	7
BP	GO:0032673	regulation of interleukin-4 production	7/2306	27/18670	0.04145	0.1637	0.126	CD83/IL33/CEBPB/HLA-E/HAVCR2/GATA3/SASH3	7
BP	GO:0035902	response to immobilization stress	7/2306	27/18670	0.04145	0.1637	0.126	HNMT/CYP1A2/LRP11/PPARG/ACTR2/FOXO4/TFF1	7
BP	GO:0043032	positive regulation of macrophage activation	7/2306	27/18670	0.04145	0.1637	0.126	IL33/IL4R/CCL3/THBS1/WNT5A/HAVCR2/CEBPA	7
BP	GO:0045671	negative regulation of osteoclast differentiation	7/2306	27/18670	0.04145	0.1637	0.126	MAFB/CCL3/UBASH3B/FBN1/TLR3/PIAS3/ZNF675	7
BP	GO:0045932	negative regulation of muscle contraction	7/2306	27/18670	0.04145	0.1637	0.126	ZC3H12A/PTGS2/RGS2/ADORA1/DOCK4/PDE5A/SRI	7
BP	GO:0046885	regulation of hormone biosynthetic process	7/2306	27/18670	0.04145	0.1637	0.126	BMP2/IL1B/NFKB1/PPARGC1A/CYP27B1/VDR/TNF	7
BP	GO:0060415	muscle tissue morphogenesis	16/2306	82/18670	0.04153	0.1637	0.126	BMP2/FZD1/RXRA/ACTC1/MYOM1/FZD2/TGFB2/WNT5A/MYOM3/MYLK/FKBP1A/ADARB1/MYH6/ENG/UBE4B/SIRT6	16
BP	GO:0001889	liver development	24/2306	135/18670	0.04154	0.1637	0.126	TNFAIP3/CLDN1/CITED2/CEBPB/JARID2/ARID5B/CFLAR/DBP/PKD2/CCND1/LIMS2/ADA/ACAT1/SULF2/SRD5A1/ITGA2/GATA6/IGF2R/ARF6/RGN/ASS1/ASNS/CEBPA/CPS1	24
BP	GO:1903825	organic acid transmembrane transport	24/2306	135/18670	0.04154	0.1637	0.126	SLC7A2/SLC43A2/PDPN/SLC7A11/AQP9/SLC38A2/ACACB/ARL6IP5/THBS1/SLC3A2/CPT1A/ACACA/RGS2/LRRC8E/RGS4/SLC38A4/SLC25A20/CLN8/PRKAB2/SLC38A6/SLC19A1/OSR1/SLC38A1/MID1IP1	24
BP	GO:1905039	carboxylic acid transmembrane transport	24/2306	135/18670	0.04154	0.1637	0.126	SLC7A2/SLC43A2/PDPN/SLC7A11/AQP9/SLC38A2/ACACB/ARL6IP5/THBS1/SLC3A2/CPT1A/ACACA/RGS2/LRRC8E/RGS4/SLC38A4/SLC25A20/CLN8/PRKAB2/SLC38A6/SLC19A1/OSR1/SLC38A1/MID1IP1	24
BP	GO:0033157	regulation of intracellular protein transport	37/2306	225/18670	0.04186	0.1649	0.1269	ZC3H12A/PTGS2/IL1B/RAB23/PDCD5/BMP4/PAK1/FYN/ANK3/RUFY3/PIK3R2/UBR5/TCF7L2/GCC2/ARIH2/RHOU/CEP290/CDK5/KCNB1/TXN/PARL/BRSK2/BAP1/SP100/GDI1/PRKCD/IWS1/CTDSPL2/GAS6/PKIG/VAMP7/PTPN11/FERMT1/ATP13A2/GRIPAP1/TMEM30B/CHP2	37
BP	GO:0010952	positive regulation of peptidase activity	33/2306	197/18670	0.04189	0.1649	0.1269	BID/PSME2/RIPK2/PRR7/PSME1/DAPK1/PDCD5/CFLAR/FYN/FAS/ARL6IP5/MTCH1/FADD/MBP/PMAIP1/F2R/ROBO1/SIRT1/TRAF2/RCN3/NKX3-1/GSN/TNF/SOX7/TNFRSF10B/ROCK2/BCL10/PPARG/PSME4/FAM162A/STAT3/PICALM/ST20	33
BP	GO:0034764	positive regulation of transmembrane transport	34/2306	204/18670	0.04195	0.165	0.127	BDKRB1/CXCL10/CCL2/CNKSR3/C3/GIP/CTSS/GSTO1/CALM1/IRS1/PKD2/CXCL11/ANK3/CXCL9/COX17/TRPC1/F2R/GJC2/ADIPOR2/CLIP3/STAC/RGN/ARF1/CALM2/ACTN4/MIR1-2/STIM1/ABL1/PTPN11/NPPA/IGF1/SRI/P2RX7/CASQ1	34
BP	GO:0006893	Golgi to plasma membrane transport	13/2306	63/18670	0.04201	0.1651	0.127	SYS1/ANK3/BBS2/OPTN/ARF1/PREPL/OSBPL5/ARF3/CCDC93/VAMP7/STEAP2/RAB31/VAMP5	13
BP	GO:0046637	regulation of alpha-beta T cell differentiation	13/2306	63/18670	0.04201	0.1651	0.127	NFKBIZ/ZC3H12A/CD83/RIPK2/SH3RF1/MYB/IL4R/SOCS1/ADA/GATA3/PRDM1/SASH3/CBFB	13
BP	GO:1902904	negative regulation of supramolecular fiber organization	25/2306	142/18670	0.04222	0.1658	0.1275	MID1/PPFIA1/LIMA1/SLIT2/MYADM/ARHGAP28/CRYAB/RDX/PLEKHH2/CLIP3/PHLDB2/CAPZA2/PFN2/EPS8/GSN/TACSTD2/IAPP/PRKCD/GMFB/MIR214/TMOD2/TAOK1/MID1IP1/CAMSAP1/WASF2	25
BP	GO:0055074	calcium ion homeostasis	71/2306	471/18670	0.04298	0.1687	0.1298	BDKRB1/CCL5/S1PR3/CXCL10/BDKRB2/CCL8/CCL7/FGF2/C1QTNF1/PLCE1/GSTO1/PTGFR/CMKLR1/CD40/FYN/CALM1/HERPUD1/PDE4D/CAMK2D/PKD2/CXCL11/CCL3/CYBA/UBASH3B/OXTR/EDN1/PTGER2/CYP27B1/CXCL9/DMPK/THADA/TRPC1/F2R/CCL1/SGCD/GRINA/LPAR1/TMEM64/GNA13/SYPL2/ITPR2/VDR/CDK5/WNT5A/ATP13A3/ADORA1/TPCN1/RGN/SLC30A1/P2RX3/CALM2/ATP2A2/MIR1-2/DLG4/STIM1/FKBP1A/IAPP/DIAPH1/NPTN/ABL1/IMMT/MCOLN1/NMUR2/ATP13A2/MIR199A2/CCR10/SRI/P2RX7/CASQ1/TMEM165/SNX10	71
BP	GO:1905477	positive regulation of protein localization to membrane	22/2306	122/18670	0.04311	0.169	0.1301	BID/PPP3CC/SQSTM1/PDCD5/PAK1/NKD2/FYN/STX3/ANK3/SSH1/PMAIP1/RAB11FIP2/CLIP3/CDK5/STAC/KCNB1/ARF6/TP63/TNF/YWHAH/TFDP1/RER1	22
BP	GO:1900408	negative regulation of cellular response to oxidative stress	12/2306	57/18670	0.04323	0.1694	0.1303	SOD2/GPR37L1/HSPB1/NCOA7/SLC7A11/FZD1/FYN/NME5/SIRT1/ATG7/TXN/OXR1	12
BP	GO:0034767	positive regulation of ion transmembrane transport	27/2306	156/18670	0.04326	0.1694	0.1304	BDKRB1/CXCL10/CCL2/CNKSR3/CTSS/GSTO1/CALM1/PKD2/CXCL11/ANK3/CXCL9/COX17/TRPC1/F2R/GJC2/STAC/RGN/ARF1/CALM2/ACTN4/MIR1-2/STIM1/ABL1/NPPA/SRI/P2RX7/CASQ1	27
BP	GO:0007033	vacuole organization	28/2306	163/18670	0.04365	0.1703	0.1311	RAB23/NDP/ABCA1/GABARAPL1/TP53INP2/CHMP4B/WIPI1/GNPTAB/RAB3GAP1/PPT1/TP53INP1/RNF5/ATG7/VPS35/ARF1/TMEM175/HOOK3/CLN8/TMEM106B/CHMP5/WDR45/PACS2/PIP4K2A/FEZ2/ATP13A2/AKTIP/P2RX7/TMEM165	28
BP	GO:0097479	synaptic vesicle localization	28/2306	163/18670	0.04365	0.1703	0.1311	ADORA2A/STX3/BACE1/RAB3GAP1/LIN7A/CDK5/SNAP47/RAB3A/SYT4/ARF1/PREPL/PFN2/DGKI/BRSK2/ATP2A2/SNPH/STXBP1/SYT1/GRIN3A/TOR1A/AP3S1/NAPB/CNIH2/DVL1/P2RX7/PCDH17/PPFIA3/PICALM	28
BP	GO:0010092	specification of animal organ identity	8/2306	33/18670	0.04374	0.1703	0.1311	SIX1/BMP4/HOXA11/SMARCD3/SPRY1/ROBO1/MEF2C/FGF10	8
BP	GO:0010464	regulation of mesenchymal cell proliferation	8/2306	33/18670	0.04374	0.1703	0.1311	SIX1/STAT1/VEGFA/BMP4/LMNA/LRP5/WNT5A/NFIB	8
BP	GO:0060603	mammary gland duct morphogenesis	8/2306	33/18670	0.04374	0.1703	0.1311	CSF1/NTN1/MSX2/LRP5/VDR/WNT5A/FGF10/TBX3	8
BP	GO:0061036	positive regulation of cartilage development	8/2306	33/18670	0.04374	0.1703	0.1311	BMP2/BMP4/BMPR2/HOXA11/SOX5/GDF5/WNT5A/GDF6	8
BP	GO:0070232	regulation of T cell apoptotic process	8/2306	33/18670	0.04374	0.1703	0.1311	CCL5/IL7R/IDO1/BMP4/FADD/ADA/WNT5A/ADAM8	8
BP	GO:1901890	positive regulation of cell junction assembly	8/2306	33/18670	0.04374	0.1703	0.1311	CLDN1/VEGFA/ROCK1/FLOT1/COL16A1/SDC4/ABL1/NPHP1	8
BP	GO:2001024	negative regulation of response to drug	8/2306	33/18670	0.04374	0.1703	0.1311	GPR37L1/ARL6IP5/RGS2/RGS4/TXN/ABAT/PTPN11/OSR1	8
BP	GO:0032007	negative regulation of TOR signaling	11/2306	51/18670	0.04418	0.1717	0.1321	SESN1/FNIP2/FNIP1/SH3BP4/ARNTL/SESN3/UBR1/SIRT1/SESN2/KPTN/SIK1	11
BP	GO:0043949	regulation of cAMP-mediated signaling	11/2306	51/18670	0.04418	0.1717	0.1321	PRKCA/GIP/CALM1/PDE4D/RGS2/LPAR1/ARRDC3/MRAP2/CALM2/PDE3B/CRTC3	11
BP	GO:0050999	regulation of nitric-oxide synthase activity	11/2306	51/18670	0.04418	0.1717	0.1321	IL1B/NPR3/DDAH1/CALM1/GCH1/GLA/NOSTRIN/CYGB/TNF/CNR2/DDAH2	11
BP	GO:0048762	mesenchymal cell differentiation	36/2306	219/18670	0.04442	0.1726	0.1328	BMP2/IL6/IL1B/DAB2/PDPN/STAT1/FAM172A/CORO1C/BMP4/WWTR1/COL1A1/RDH10/MSX2/EDN1/SDCBP/SEMA4D/TGFB2/PHLDB1/SPRY1/SNAI2/HAS2/EFNB1/MEF2C/PHLDB2/DACT3/WNT5A/RANBP3L/DDX5/RTN4/ENG/FGF10/SEMA4F/OSR1/SDHAF2/AKNA/GLIPR2	36
BP	GO:0019048	modulation by virus of host morphology or physiology	9/2306	39/18670	0.04469	0.173	0.1331	ZC3H12A/CCL8/RXRA/EIF2AK4/HIPK2/KPNA3/ATG7/BCL2L1/KPNA2	9
BP	GO:0033146	regulation of intracellular estrogen receptor signaling pathway	9/2306	39/18670	0.04469	0.173	0.1331	PAK1/LBH/YAP1/CARM1/TP63/KCTD6/GPAM/UFSP2/CBFB	9
BP	GO:0033574	response to testosterone	9/2306	39/18670	0.04469	0.173	0.1331	PSPH/CFLAR/THBS1/EDN1/SRD5A1/SIRT1/NKX3-1/BGLAP/ROCK2	9
BP	GO:0072350	tricarboxylic acid metabolic process	9/2306	39/18670	0.04469	0.173	0.1331	ACO1/IDH1/GLUD1/FH/ASS1/PDHB/SDHD/SUCLA2/SDHAF2	9
BP	GO:0072595	maintenance of protein localization in organelle	9/2306	39/18670	0.04469	0.173	0.1331	HK2/BCL3/CDK5/TXN/TOPORS/SP100/ARL2BP/RER1/MORC3	9
BP	GO:0032456	endocytic recycling	10/2306	45/18670	0.04474	0.173	0.1331	EHD4/RAB13/EPS15/STX6/SNX4/MICALL1/EHD1/ARHGAP1/ARF6/CCDC93	10
BP	GO:0048538	thymus development	10/2306	45/18670	0.04474	0.173	0.1331	MAFB/JARID2/SIX1/FADD/MAD1L1/SIX4/GATA3/ABL1/FGF10/CRKL	10
BP	GO:0006650	glycerophospholipid metabolic process	50/2306	319/18670	0.04486	0.1734	0.1334	PLD1/OSBPL10/LPIN1/FGF2/PIK3CD/GPD1L/PLSCR1/PLA2G4A/PDGFRB/SOCS1/SOCS3/RAB38/FABP3/PISD/PLA2G4C/PIGV/DBI/PIK3R2/PTPN13/PIK3R3/IMPA2/RAB4A/PLEKHA3/CPNE3/EFR3A/PLA2G12A/ARF1/OSBPL5/ARF3/ABHD5/SOCS2/ALDH5A1/ABHD3/GPAM/MPPE1/INPP5B/PIGK/PIGS/CHKB/IP6K3/PIP4K2A/FAR1/INPP1/PI4K2B/SH3YL1/SBF1/PLEKHA4/CAPN2/LCLAT1/STARD7	50
BP	GO:0051966	regulation of synaptic transmission, glutamatergic	14/2306	70/18670	0.04523	0.1746	0.1343	PTGS2/CCL2/ADORA2A/OXTR/RAB3GAP1/MEF2C/CDK5/ADORA1/DGKI/TNF/STXBP1/TSHZ3/GRM2/SYT1	14
BP	GO:0060395	SMAD protein signal transduction	14/2306	70/18670	0.04523	0.1746	0.1343	BMP2/DAB2/BMP4/WWTR1/AFP/INHBB/HIPK2/TGFB2/GDF5/GDF15/SUB1/GDF6/ATOH8/SMAD9	14
BP	GO:0006606	protein import into nucleus	25/2306	143/18670	0.04538	0.1747	0.1344	NFKBIA/ZC3H12A/PTGS2/RAB23/BMP4/NUP133/LMNA/PIK3R2/UBR5/ARNTL/KPNA3/RPAIN/APPL2/PRKCD/PPP3CA/NXT1/PKIG/CDKN1A/KPNA2/RANBP17/NUP35/FERMT1/CBLB/STAT3/CHP2	25
BP	GO:0035296	regulation of tube diameter	25/2306	143/18670	0.04538	0.1747	0.1344	SOD2/ICAM1/PTGS2/ITGA1/BDKRB2/ADORA2A/ROCK1/BMPR2/GCH1/OXTR/EDN1/F2R/RGS2/BBS2/ADORA1/PTPRM/DOCK4/UTS2R/ADRB3/CPS1/ROCK2/HBB/NPPA/SERPINF2/ADRA2A	25
BP	GO:0050880	regulation of blood vessel size	25/2306	143/18670	0.04538	0.1747	0.1344	SOD2/ICAM1/PTGS2/ITGA1/BDKRB2/ADORA2A/ROCK1/BMPR2/GCH1/OXTR/EDN1/F2R/RGS2/BBS2/ADORA1/PTPRM/DOCK4/UTS2R/ADRB3/CPS1/ROCK2/HBB/NPPA/SERPINF2/ADRA2A	25
BP	GO:0097746	regulation of blood vessel diameter	25/2306	143/18670	0.04538	0.1747	0.1344	SOD2/ICAM1/PTGS2/ITGA1/BDKRB2/ADORA2A/ROCK1/BMPR2/GCH1/OXTR/EDN1/F2R/RGS2/BBS2/ADORA1/PTPRM/DOCK4/UTS2R/ADRB3/CPS1/ROCK2/HBB/NPPA/SERPINF2/ADRA2A	25
BP	GO:0032755	positive regulation of interleukin-6 production	18/2306	96/18670	0.04541	0.1747	0.1344	IL6/IL1B/RIPK2/IL33/IFIH1/EREG/DDX58/CYBA/MAPK13/MBP/F2R/WNT5A/TNF/TLR3/PTPN11/TICAM1/STAT3/P2RX7	18
BP	GO:0032535	regulation of cellular component size	57/2306	370/18670	0.04551	0.1749	0.1346	ICAM1/KCNN4/NTN1/IL7R/ARPC1A/ZFYVE27/DBN1/VEGFA/PPP1R15A/PAK1/CDC42EP1/ARHGAP18/LIMA1/ACTR3/CDC42EP3/SLIT2/BMPR2/MYADM/RUFY3/ARHGAP28/SLC12A2/FMN2/EDN1/RDX/DSTN/SEMA4D/PLEKHH2/IFRD1/ARPC2/CDK5/WNT5A/CAPZA2/ARF6/ARF1/PFN2/EPS8/GSN/TMEM123/CLN8/PEX11G/GDI1/PRKCD/RTN4/PEX11B/GMFB/ABL1/MIR214/PDXP/ACTR2/TMOD2/ATP13A2/SEMA4F/CDH4/P2RX7/PLEKHG2/MAGEL2/PICALM	57
BP	GO:0007569	cell aging	21/2306	116/18670	0.04561	0.1749	0.1346	ICAM1/NAMPT/ID2/CDK6/PLK2/LMNA/ARNTL/NUAK1/NSMCE2/SIRT1/TP63/BGLAP/NEK6/PRKCD/HLA-G/SERPINE1/ABL1/CDKN1A/ENG/TBX3/MORC3	21
BP	GO:0021782	glial cell development	21/2306	116/18670	0.04561	0.1749	0.1346	IL6/IL1B/ID2/ADORA2A/CDK6/IFNGR1/BACE2/MXRA8/ARHGEF10/CNTNAP1/ROR1/ERCC2/LPAR1/CDK5/HES5/GSN/TNF/EIF2B5/EIF2B4/PHGDH/TSPAN2	21
BP	GO:0010226	response to lithium ion	6/2306	22/18670	0.04585	0.1749	0.1346	PTGS2/ID2/ADCY7/XRCC4/EIF2B5/CEBPA	6
BP	GO:0032069	regulation of nuclease activity	6/2306	22/18670	0.04585	0.1749	0.1346	OAS1/OAS3/OAS2/OASL/SIRT1/PRKCD	6
BP	GO:0032727	positive regulation of interferon-alpha production	6/2306	22/18670	0.04585	0.1749	0.1346	RIPK2/IFIH1/STAT1/IRF7/DDX58/TLR3	6
BP	GO:0042359	vitamin D metabolic process	6/2306	22/18670	0.04585	0.1749	0.1346	IL1B/NFKB1/CYP27B1/SNAI2/VDR/TNF	6
BP	GO:0043496	regulation of protein homodimerization activity	6/2306	22/18670	0.04585	0.1749	0.1346	ITGA4/MEF2C/TRAF2/ARF6/CRBN/TICAM1	6
BP	GO:0045649	regulation of macrophage differentiation	6/2306	22/18670	0.04585	0.1749	0.1346	LIF/ID2/TRIB1/CSF1/PRKCA/FADD	6
BP	GO:0045723	positive regulation of fatty acid biosynthetic process	6/2306	22/18670	0.04585	0.1749	0.1346	PTGS2/IL1B/ELOVL5/ABCD1/RGN/MID1IP1	6
BP	GO:0046058	cAMP metabolic process	6/2306	22/18670	0.04585	0.1749	0.1346	PDE4D/PTHLH/ADCY7/ADCY9/ADCY3/PDE4B	6
BP	GO:0060487	lung epithelial cell differentiation	6/2306	22/18670	0.04585	0.1749	0.1346	KLF2/GATA6/THRA/YAP1/FGF10/NFIB	6
BP	GO:0060547	negative regulation of necrotic cell death	6/2306	22/18670	0.04585	0.1749	0.1346	BIRC3/BIRC2/CFLAR/FADD/RBCK1/MIR214	6
BP	GO:0097205	renal filtration	6/2306	22/18670	0.04585	0.1749	0.1346	SULF2/MYO1E/F2R/ADORA1/SULF1/GAS6	6
BP	GO:0045861	negative regulation of proteolysis	56/2306	363/18670	0.04604	0.1755	0.1351	BIRC3/PTGS2/SERPINA9/SERPINB2/SH3RF1/ADORA2A/SERPINB8/RECK/BIRC2/C3/TNFAIP8/VEGFA/ROCK1/CFLAR/CD44/HERPUD1/KLF4/PI3/THBS1/ANXA8/CRIM1/CRYAB/FNIP1/SDCBP/HIPK2/CAST/MAP1A/TM4SF20/MMP9/CDK5/MIR19B2/TRIM21/COL6A3/TIMP4/UBXN1/SPINK6/USP14/CLN8/ITIH1/SERPINH1/SERPINB1/BIRC6/MAGEA3/SPINK1/WFDC3/SERPINE1/HMSD/GAS6/SERPINA4/UBE2Z/SERPINA3/CSTB/SERPINA1/SERPINF2/PICALM/PSMF1	56
BP	GO:0046434	organophosphate catabolic process	40/2306	248/18670	0.04621	0.1761	0.1355	PPARGC1A/SLC2A6/GPD1L/PLA2G4A/HK2/ENO2/ADPGK/PLA2G4C/PDE4D/NUP133/PDE1A/IDH1/AMPD3/PGM2L1/NUDT18/NUDT7/ADA/ACAT1/NT5C2/ENPP1/NUDT11/LIPG/IMPA2/NUDT1/ABCD1/PRKCD/INPP5B/PGAM4/MBD4/PDE4B/PDXP/NUP35/INPP1/PDE5A/IGF1/STAT3/ALDOC/P2RX7/HINT1/SIRT6	40
BP	GO:0048588	developmental cell growth	38/2306	234/18670	0.04668	0.1777	0.1367	NTN1/ZFYVE27/DBN1/AUTS2/VEGFA/PAK1/VCL/SLIT2/BMPR2/RUFY3/ITGA4/EDN1/EIF2AK4/SEMA4D/ARIH2/RGS2/IFRD1/CDK5/MIR19B2/WNT5A/RGS4/SYT4/FLRT3/PDLIM5/GDI1/SYT1/RTN4/ABL1/NPPA/SEMA4F/MIR199A2/IGF1/CDH4/DVL1/TMEM108/RAPH1/USP9X/SIRT6	38
BP	GO:0032652	regulation of interleukin-1 production	19/2306	103/18670	0.04695	0.1786	0.1374	ZC3H12A/TNFAIP3/S1PR3/RIPK2/HSPB1/PANX1/PANX2/CCL3/GSDMD/SIRPA/F2R/ERRFI1/WNT5A/HAVCR2/SERPINB1/GAS6/PYDC2/IGF1/P2RX7	19
BP	GO:0030032	lamellipodium assembly	13/2306	64/18670	0.04699	0.1786	0.1374	FSCN1/KIT/AUTS2/VCL/SLIT2/CCDC88A/AKIRIN1/ARPC2/BIN3/MIR214/CDC42/SH2B1/WASF2	13
BP	GO:0043297	apical junction assembly	13/2306	64/18670	0.04699	0.1786	0.1374	CLDN1/ROCK1/RAB13/VCL/SNAI2/TNF/ACTN4/ROCK2/PKN2/TJP1/PDCD6IP/NPHP1/CBFB	13
BP	GO:0010950	positive regulation of endopeptidase activity	30/2306	178/18670	0.0471	0.1788	0.1376	BID/PSME2/RIPK2/PRR7/PSME1/DAPK1/PDCD5/FYN/FAS/ARL6IP5/MTCH1/FADD/MBP/PMAIP1/F2R/ROBO1/SIRT1/TRAF2/NKX3-1/GSN/TNF/SOX7/TNFRSF10B/ROCK2/BCL10/PPARG/FAM162A/STAT3/PICALM/ST20	30
BP	GO:0022406	membrane docking	30/2306	178/18670	0.0471	0.1788	0.1376	ICAM1/VCAM1/AHI1/ROCK1/ESYT1/STX3/STX6/SCFD2/DCTN1/CSNK1E/CEP290/CEP250/OFD1/KCNB1/RAB3A/CEP78/DYNLL1/TMEM216/SNPH/STXBP1/SYT1/STX16/MARK4/TSNARE1/DCTN3/CEP63/PPFIA3/VPS45/NPHP1/SNX3	30
BP	GO:1902749	regulation of cell cycle G2/M phase transition	35/2306	213/18670	0.04715	0.1789	0.1376	PSME2/PSMA6/PSMB10/FHL1/PSMB8/PSMB7/PSME1/PSMB9/CCND1/PSMA3/CDC25A/SMARCD3/CDC14B/DCTN1/CSNK1E/PSMA1/CEP290/CEP250/PSMB2/OFD1/MIR19B2/PSMB3/CEP78/DYNLL1/PSMA8/ZNF830/ZFYVE19/PSME4/PSMB5/DCTN3/CEP63/TAOK1/UIMC1/FOXO4/PSMF1	35
BP	GO:0010717	regulation of epithelial to mesenchymal transition	17/2306	90/18670	0.04782	0.1812	0.1394	BMP2/IL6/IL1B/DAB2/PDPN/BMP4/WWTR1/COL1A1/TCF7L2/SDCBP/TGFB2/PHLDB1/PHLDB2/DACT3/ENG/SDHAF2/GLIPR2	17
BP	GO:0042475	odontogenesis of dentin-containing tooth	17/2306	90/18670	0.04782	0.1812	0.1394	BMP2/CSF1/FOXO1/BMP4/MSX2/LHX8/TP63/TNC/RSPO2/STIM1/DLX3/SERPINE1/ANKRD11/FGF10/TNFRSF11B/ROGDI/ITGA6	17
BP	GO:0090596	sensory organ morphogenesis	41/2306	256/18670	0.0484	0.1833	0.141	LRIG1/AHI1/NTN1/MEIS1/MAFB/SIX1/INSIG2/ALDH1A3/VEGFA/BMP4/IRX5/HOXC13/BCAR3/TTC39C/EDN1/COL5A2/FZD2/HIPK2/LRP5/CEP290/SIX4/WNT5A/SHROOM2/FJX1/PRKRA/FBN1/PTK7/TOPORS/OSR2/PTPRM/ATP8A2/GATA3/ARID1A/PRDM1/RDH13/FGF10/STAT3/DVL1/OSR1/DVL2/COL5A1	41
BP	GO:0042093	T-helper cell differentiation	12/2306	58/18670	0.04862	0.1838	0.1414	NFKBIZ/ZC3H12A/IL6/RELB/RIPK2/IL18R1/MYB/IL4R/STAT6/BCL3/GATA3/STAT3	12
BP	GO:0071385	cellular response to glucocorticoid stimulus	12/2306	58/18670	0.04862	0.1838	0.1414	ICAM1/FOXO1/CFLAR/ZFP36/EDN1/SRD5A1/ZFP36L2/SMYD3/ERRFI1/GJB2/ABCC2/ASS1	12
BP	GO:1904589	regulation of protein import	12/2306	58/18670	0.04862	0.1838	0.1414	ZC3H12A/PTGS2/RAB23/PDCD5/BMP4/PIK3R2/UBR5/ARHGEF5/PRKCD/PKIG/FERMT1/CHP2	12
BP	GO:0035150	regulation of tube size	25/2306	144/18670	0.04872	0.184	0.1416	SOD2/ICAM1/PTGS2/ITGA1/BDKRB2/ADORA2A/ROCK1/BMPR2/GCH1/OXTR/EDN1/F2R/RGS2/BBS2/ADORA1/PTPRM/DOCK4/UTS2R/ADRB3/CPS1/ROCK2/HBB/NPPA/SERPINF2/ADRA2A	25
BP	GO:0043254	regulation of protein complex assembly	70/2306	467/18670	0.04891	0.1845	0.1419	BID/ICAM1/MMP1/CSF2/MMP3/ABCA1/FSCN1/BIRC2/ARPC1A/DBN1/VEGFA/PAK1/GBP5/CDC42EP1/ARHGAP18/ACTR3/RPA2/CDC42EP3/SLIT2/MYADM/FNIP2/BCLAF1/ARHGAP28/FMN2/CRYAB/RDX/FNIP1/PMAIP1/DR1/ERCC2/DCTN1/CAND1/DDB2/MITF/THRA/DNAJC15/CLIP3/ARPC2/CAPZA2/VPS35/RAB3A/ARF6/CRBN/ARF1/PFN2/ARHGEF5/EPS8/GSN/RNF4/TNF/SUB1/STXBP1/IAPP/ASAP1/PRKCD/GTF2H5/GMFB/ABL1/MIR214/PTPN11/ACTR2/TMOD2/PYDC2/CDC42/NAPB/ZNF451/PLEKHG2/ANKRD27/MAGEL2/CAMSAP1	70
BP	GO:0055088	lipid homeostasis	26/2306	151/18670	0.04918	0.1845	0.1419	ABCA1/ACOX2/GIP/LIMA1/FABP3/NFE2L1/THADA/LIPG/ACACA/TLCD1/SOAT1/MALL/EHD1/LRP5/ABCD1/SIRT1/MIR19B2/ADORA1/RCN3/SESN2/ABHD5/CEBPA/RTN4/PPARG/ACOXL/MYLIP	26
BP	GO:0002693	positive regulation of cellular extravasation	5/2306	17/18670	0.04954	0.1845	0.1419	ICAM1/FADD/ITGA4/PDGFD/ADAM8	5
BP	GO:0006577	amino-acid betaine metabolic process	5/2306	17/18670	0.04954	0.1845	0.1419	SLC22A4/CROT/CPT1A/ALDH7A1/ACADM	5
BP	GO:0006750	glutathione biosynthetic process	5/2306	17/18670	0.04954	0.1845	0.1419	SLC7A11/CHAC2/HAGH/CNDP2/MGST2	5
BP	GO:0006895	Golgi to endosome transport	5/2306	17/18670	0.04954	0.1845	0.1419	SYS1/EPS15/SORT1/WIPI1/KLHL20	5
BP	GO:0032780	negative regulation of ATPase activity	5/2306	17/18670	0.04954	0.1845	0.1419	PPIF/THADA/CNN3/RGN/PXK	5
BP	GO:0032966	negative regulation of collagen biosynthetic process	5/2306	17/18670	0.04954	0.1845	0.1419	IL6/ERRFI1/CYGB/PPARG/MIR218-1	5
BP	GO:0048243	norepinephrine secretion	5/2306	17/18670	0.04954	0.1845	0.1419	ADORA2A/OXTR/NISCH/KCNB1/ADRA2A	5
BP	GO:0051284	positive regulation of sequestering of calcium ion	5/2306	17/18670	0.04954	0.1845	0.1419	GSTO1/CALM1/PKD2/CALM2/SRI	5
BP	GO:0061952	midbody abscission	5/2306	17/18670	0.04954	0.1845	0.1419	CHMP1B/CHMP4B/CHMP5/MITD1/PDCD6IP	5
BP	GO:0071360	cellular response to exogenous dsRNA	5/2306	17/18670	0.04954	0.1845	0.1419	IFIH1/IFIT1/DDX58/FLOT1/TLR3	5
BP	GO:0072673	lamellipodium morphogenesis	5/2306	17/18670	0.04954	0.1845	0.1419	PDPN/CORO1C/CD44/PLEKHO1/WASF2	5
BP	GO:1902683	regulation of receptor localization to synapse	5/2306	17/18670	0.04954	0.1845	0.1419	DBN1/GPC4/NPTN/CNIH2/GRIPAP1	5
BP	GO:0051591	response to cAMP	18/2306	97/18670	0.04957	0.1845	0.1419	BIRC2/AHR/STAT1/AQP9/EEF2K/COL1A1/PKD2/SRD5A1/NDUFS4/CARM1/HCN4/ITPR2/JUNB/ASS1/SPARC/CPS1/PER1/SLC26A3	18
BP	GO:0003180	aortic valve morphogenesis	7/2306	28/18670	0.04958	0.1845	0.1419	ROCK1/BMP4/SLIT2/SNAI2/ROBO1/GATA3/ROCK2	7
BP	GO:0006972	hyperosmotic response	7/2306	28/18670	0.04958	0.1845	0.1419	AKR1B1/CLDN1/SLC2A1/SLC12A2/HNMT/ERRFI1/TLR3	7
BP	GO:0010818	T cell chemotaxis	7/2306	28/18670	0.04958	0.1845	0.1419	CCL5/CXCL10/PIK3CD/CXCL11/CCL3/SLC12A2/WNT5A	7
BP	GO:0032647	regulation of interferon-alpha production	7/2306	28/18670	0.04958	0.1845	0.1419	RIPK2/IFIH1/STAT1/IRF7/DDX58/HAVCR2/TLR3	7
BP	GO:0034698	response to gonadotropin	7/2306	28/18670	0.04958	0.1845	0.1419	ICAM1/PPARGC1A/SRD5A1/GATA6/GJB2/ASNS/PAPPA	7
BP	GO:1900543	negative regulation of purine nucleotide metabolic process	7/2306	28/18670	0.04958	0.1845	0.1419	PID1/PPARGC1A/PPIF/PDE12/DNAJC15/STAT3/SIRT6	7
BP	GO:1902003	regulation of amyloid-beta formation	7/2306	28/18670	0.04958	0.1845	0.1419	IFNGR1/ROCK1/TNF/ROCK2/TMED10/IGF1/PICALM	7
BP	GO:1902745	positive regulation of lamellipodium organization	7/2306	28/18670	0.04958	0.1845	0.1419	FSCN1/CORO1C/AUTS2/AKIRIN1/ARPC2/CDC42/WASF2	7
BP	GO:1903792	negative regulation of anion transport	7/2306	28/18670	0.04958	0.1845	0.1419	ARL6IP5/THBS1/RGS2/RGS4/ADORA1/ABAT/OSR1	7
BP	GO:1990776	response to angiotensin	7/2306	28/18670	0.04958	0.1845	0.1419	PTGS2/NFKB1/AGTRAP/ROCK1/CYBA/PRKCD/ROCK2	7
BP	GO:0043010	camera-type eye development	49/2306	314/18670	0.04976	0.185	0.1424	NINJ1/NDP/AHI1/MEIS1/SLC7A11/ALDH1A3/VEGFA/BMP4/PDGFRB/SIX5/IRX5/RDH10/BCAR3/RXRA/RHOJ/BMPR2/KLF4/SMARCD3/CRYAB/CRYGS/RAB3GAP1/MYOM1/HIPK2/TGFB2/MITF/WNT5B/LRP5/IMPDH2/WNT5A/SHROOM2/HES5/FJX1/CDKN1C/FBN1/TOPORS/CLN8/FZD4/OSR2/PTPRM/ATP8A2/GATA3/COL4A1/ARID1A/MAX/RDH13/FGF10/MYH10/MAB21L2/NPHP1	49
BP	GO:0016051	carbohydrate biosynthetic process	35/2306	214/18670	0.04992	0.1852	0.1425	AKR1B1/NFKB1/PPARGC1A/FOXO1/SLC2A1/PPP1R3F/ENO2/UGP2/IRS1/PGM2L1/DYRK2/ENPP1/CLTC/KAT2B/IMPA2/CSGALNACT1/HAS2/CSGALNACT2/SIRT1/RGN/SESN2/MGAT2/HAS1/GYG1/CHST8/HAS3/GYS2/EXT1/HS2ST1/SLC35B4/SIK1/IGF1/GNMT/ALDOC/ST3GAL4	35
BP	GO:0060421	positive regulation of heart growth	11/2306	52/18670	0.05003	0.1852	0.1425	BASP1/FGF2/ACACB/PIM1/EDN1/GATA6/YAP1/MEF2C/MIR19B2/MIR199A2/IGF1	11
BP	GO:0008064	regulation of actin polymerization or depolymerization	30/2306	179/18670	0.05015	0.1852	0.1425	ICAM1/ARPC1A/DBN1/CDC42EP1/ARHGAP18/LIMA1/ACTR3/CDC42EP3/SLIT2/MYADM/ARHGAP28/FMN2/RDX/DSTN/PLEKHH2/ARPC2/CAPZA2/ARF6/ARF1/PFN2/EPS8/GSN/PRKCD/GMFB/MIR214/PDXP/ACTR2/TMOD2/PLEKHG2/MAGEL2	30
BP	GO:0070507	regulation of microtubule cytoskeleton organization	31/2306	186/18670	0.05021	0.1852	0.1425	CHMP1B/PLK2/MID1/PAK1/CHMP4B/TRIM37/CYLD/DIXDC1/CLTC/STMN3/GPSM2/DCTN1/KAT2B/PHLDB1/MAP1A/CLIP3/CEP250/PHLDB2/RNF4/CDK2AP2/CHMP5/MAPRE2/ABL1/ROCK2/MARK4/RASSF1/TAOK1/BICD2/MID1IP1/PDCD6IP/CAMSAP1	31
BP	GO:0001838	embryonic epithelial tube formation	22/2306	124/18670	0.0503	0.1852	0.1425	SIX1/BMP4/FZD1/IRX3/SHROOM3/STK4/FZD2/TGFB2/SIX4/WNT5A/HES5/PTK7/GATA3/ARID1A/SDC4/ABL1/BCL10/RALA/MIB1/DVL1/OSR1/DVL2	22
BP	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling	22/2306	124/18670	0.0503	0.1852	0.1425	CCL5/IER3/KIT/PIK3CD/FBXL2/PDGFRB/FYN/KLF4/PTPN13/SEMA4D/PDGFD/F2R/TGFB2/SIRT1/NKX3-1/TNF/PDGFC/PPP2R5C/PIP4K2A/IGF1/NEDD4/PRR5	22
BP	GO:0048284	organelle fusion	22/2306	124/18670	0.0503	0.1852	0.1425	PID1/TAP1/TAP2/SAMD9L/NKD2/BET1/VAMP4/STX3/STX6/TBC1D4/SNAP47/RAB3A/SYT4/TMEM175/SAMD9/STXBP1/SYT1/STX16/VAMP7/TAPBP/TSNARE1/ANKRD27	22
BP	GO:0051101	regulation of DNA binding	22/2306	124/18670	0.0503	0.1852	0.1425	NFKBIA/LIF/ID2/ZFP90/KLF4/EDF1/MSX2/HIPK2/ERCC2/ITGA2/MMP9/BCL3/TXN/SUMO3/SP100/TRIM6/GATA3/PPARG/ID3/IGF1/SRI/ZNF675	22
BP	GO:0045445	myoblast differentiation	16/2306	84/18670	0.05032	0.1852	0.1425	CXCL10/MBNL1/PITX1/EPAS1/BMP4/TCF7L2/CXCL9/IFRD1/MEF2C/AKIRIN1/RANBP3L/DDX5/TNF/ID3/IGF1/TBX3	16
BP	GO:1902803	regulation of synaptic vesicle transport	16/2306	84/18670	0.05032	0.1852	0.1425	ADORA2A/BACE1/RAB3GAP1/CDK5/RAB3A/SYT4/PREPL/PFN2/DGKI/ATP2A2/STXBP1/SYT1/GRIN3A/NAPB/CNIH2/DVL1	16
BP	GO:0002371	dendritic cell cytokine production	4/2306	12/18670	0.0508	0.1852	0.1425	KIT/DDX58/TLR3/TICAM1	4
BP	GO:0002551	mast cell chemotaxis	4/2306	12/18670	0.0508	0.1852	0.1425	KIT/PIK3CD/VEGFA/PGF	4
BP	GO:0006216	cytidine catabolic process	4/2306	12/18670	0.0508	0.1852	0.1425	APOBEC3G/APOBEC3H/CDADC1/APOBEC3F	4
BP	GO:0009086	methionine biosynthetic process	4/2306	12/18670	0.0508	0.1852	0.1425	MTHFD2L/MTR/BHMT2/MTAP	4
BP	GO:0009972	cytidine deamination	4/2306	12/18670	0.0508	0.1852	0.1425	APOBEC3G/APOBEC3H/CDADC1/APOBEC3F	4
BP	GO:0014889	muscle atrophy	4/2306	12/18670	0.0508	0.1852	0.1425	PPARGC1A/CFLAR/IL15/GSN	4
BP	GO:0016188	synaptic vesicle maturation	4/2306	12/18670	0.0508	0.1852	0.1425	RAB3A/DLG4/STXBP1/PICALM	4
BP	GO:0033197	response to vitamin E	4/2306	12/18670	0.0508	0.1852	0.1425	COL1A1/CCND1/ADA/PPARG	4
BP	GO:0046087	cytidine metabolic process	4/2306	12/18670	0.0508	0.1852	0.1425	APOBEC3G/APOBEC3H/CDADC1/APOBEC3F	4
BP	GO:0051095	regulation of helicase activity	4/2306	12/18670	0.0508	0.1852	0.1425	IFIT1/POT1/SIRT1/MNAT1	4
BP	GO:0060707	trophoblast giant cell differentiation	4/2306	12/18670	0.0508	0.1852	0.1425	LIF/SOCS3/NR2F2/PRDM1	4
BP	GO:0070243	regulation of thymocyte apoptotic process	4/2306	12/18670	0.0508	0.1852	0.1425	BMP4/ADA/WNT5A/ADAM8	4
BP	GO:0070486	leukocyte aggregation	4/2306	12/18670	0.0508	0.1852	0.1425	IL1B/CD44/SEMA4D/HAS2	4
BP	GO:0071888	macrophage apoptotic process	4/2306	12/18670	0.0508	0.1852	0.1425	CCL5/IRF7/MEF2C/SIRT1	4
BP	GO:0072178	nephric duct morphogenesis	4/2306	12/18670	0.0508	0.1852	0.1425	AHI1/BMP4/GATA3/OSR1	4
BP	GO:0072578	neurotransmitter-gated ion channel clustering	4/2306	12/18670	0.0508	0.1852	0.1425	SLC7A11/SSH1/LHFPL4/DLG4	4
BP	GO:0090148	membrane fission	4/2306	12/18670	0.0508	0.1852	0.1425	MX1/MX2/CORO1C/CHMP4B	4
BP	GO:0090331	negative regulation of platelet aggregation	4/2306	12/18670	0.0508	0.1852	0.1425	C1QTNF1/UBASH3B/ABAT/PRKCD	4
BP	GO:0097531	mast cell migration	4/2306	12/18670	0.0508	0.1852	0.1425	KIT/PIK3CD/VEGFA/PGF	4
BP	GO:1903894	regulation of IRE1-mediated unfolded protein response	4/2306	12/18670	0.0508	0.1852	0.1425	FICD/DNAJB9/TMEM33/BFAR	4
BP	GO:1903909	regulation of receptor clustering	4/2306	12/18670	0.0508	0.1852	0.1425	SLC7A11/SSH1/GSN/CRKL	4
BP	GO:1905461	positive regulation of vascular associated smooth muscle cell apoptotic process	4/2306	12/18670	0.0508	0.1852	0.1425	SOD2/STK4/MIR1-2/PPARG	4
BP	GO:2000650	negative regulation of sodium ion transmembrane transporter activity	4/2306	12/18670	0.0508	0.1852	0.1425	CAMK2D/HECW2/OSR1/NEDD4	4
BP	GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	19/2306	104/18670	0.05105	0.1856	0.1428	BMP2/CITED2/DAB2/BMP4/BMPR2/THBS1/MSX2/INHBB/SDCBP/HIPK2/TGFB2/GDF5/SULF1/GDF15/HES5/CDKN1C/ENG/FERMT1/GDF6	19
BP	GO:0001504	neurotransmitter uptake	10/2306	46/18670	0.05108	0.1856	0.1428	SLC7A11/ARL6IP5/RGS2/FLOT1/RGS4/CLN8/SLC22A3/TOR1A/SLC29A1/SLC38A1	10
BP	GO:0043330	response to exogenous dsRNA	10/2306	46/18670	0.05108	0.1856	0.1428	NFKBIA/RIPK2/IFIH1/IFIT1/IRAK3/DDX58/SLC3A2/FLOT1/TLR3/TICAM1	10
BP	GO:0044003	modification by symbiont of host morphology or physiology	10/2306	46/18670	0.05108	0.1856	0.1428	ZC3H12A/TNIP1/CCL8/RXRA/EIF2AK4/HIPK2/KPNA3/ATG7/BCL2L1/KPNA2	10
BP	GO:0045776	negative regulation of blood pressure	10/2306	46/18670	0.05108	0.1856	0.1428	SOD2/BDKRB1/GPR37L1/BMPR2/GCH1/ADM2/ADORA1/ABAT/ADRB3/NPPA	10
BP	GO:0050706	regulation of interleukin-1 beta secretion	10/2306	46/18670	0.05108	0.1856	0.1428	ZC3H12A/TNFAIP3/RIPK2/PANX1/CCL3/GSDMD/WNT5A/SERPINB1/PYDC2/P2RX7	10
BP	GO:0007435	salivary gland morphogenesis	8/2306	34/18670	0.05124	0.1856	0.1428	TGFB2/SNAI2/POLB/NKX3-1/TNF/PLXND1/FGF10/NFIB	8
BP	GO:0010574	regulation of vascular endothelial growth factor production	8/2306	34/18670	0.05124	0.1856	0.1428	PTGS2/IL6/IL1B/IL1A/C3/IL6ST/SULF2/SULF1	8
BP	GO:0031128	developmental induction	8/2306	34/18670	0.05124	0.1856	0.1428	BMP2/SIX1/BMP4/HOXA11/HIPK2/SPRY1/ROBO1/FGF10	8
BP	GO:0034205	amyloid-beta formation	8/2306	34/18670	0.05124	0.1856	0.1428	IFNGR1/ROCK1/PSENEN/TNF/ROCK2/TMED10/IGF1/PICALM	8
BP	GO:0043094	cellular metabolic compound salvage	8/2306	34/18670	0.05124	0.1856	0.1428	TYMP/AMPD3/ADA/BHMT2/MTAP/PRTFDC1/TK2/DCK	8
BP	GO:0042036	negative regulation of cytokine biosynthetic process	9/2306	40/18670	0.05158	0.1865	0.1435	IL6/NFKB1/TRIB2/KLF4/ZFP36/INHBB/ERRFI1/ASB1/BCL3	9
BP	GO:0046621	negative regulation of organ growth	9/2306	40/18670	0.05158	0.1865	0.1435	MEIS1/JARID2/PAK1/WWC1/STK4/RGS2/RGS4/MIR1-2/MIR199A2	9
BP	GO:0071470	cellular response to osmotic stress	9/2306	40/18670	0.05158	0.1865	0.1435	AKR1B1/PTGS2/RELB/BDKRB2/SLC2A1/PKD2/ERRFI1/LRRC8E/MYLK	9
BP	GO:0042119	neutrophil activation	74/2306	498/18670	0.0516	0.1865	0.1435	CXCL1/CXCL6/CCL5/OLR1/TNFAIP6/PLD1/NFKB1/ANPEP/PSMB7/PYGL/C3/TNFRSF1B/ROCK1/CNN2/CTSS/TOM1/VCL/FRMPD3/PLAU/CD44/CD58/FTH1/IDH1/AMPD3/CYBA/IL15/GLA/COMMD3/GSDMD/GLB1/SDCBP/SIRPA/METTL7A/PRG3/CAND1/DNAJC3/PPIA/IGF2R/MMP9/S100A11/CEP290/IMPDH2/CPNE3/CRISPLD2/ATG7/RAB3A/PAFAH1B2/RAB18/GSN/HMOX2/CEACAM3/DYNLL1/ACTR10/SERPINB1/GYG1/RAB9B/FRK/PTX3/DIAPH1/PRKCD/AGA/HBB/VAMP7/ACTR2/TBC1D10C/SERPINA3/GCA/CSTB/ALDOC/SERPINA1/RAB31/UBR4/HLA-H/ADAM8	74
BP	GO:0061008	hepaticobiliary system development	24/2306	138/18670	0.05172	0.1868	0.1437	TNFAIP3/CLDN1/CITED2/CEBPB/JARID2/ARID5B/CFLAR/DBP/PKD2/CCND1/LIMS2/ADA/ACAT1/SULF2/SRD5A1/ITGA2/GATA6/IGF2R/ARF6/RGN/ASS1/ASNS/CEBPA/CPS1	24
BP	GO:0035305	negative regulation of dephosphorylation	20/2306	111/18670	0.0523	0.1886	0.1451	ENSA/PPP4R4/PPP1R15A/ROCK1/SET/SEMA4D/PPP1R9B/TGFB2/PHACTR2/CCDC8/RGN/TNF/FKBP1A/TMEM225/ROCK2/ELL/PPP1R14C/FARP1/SH3RF2/MYO1D	20
BP	GO:0010594	regulation of endothelial cell migration	37/2306	229/18670	0.05231	0.1886	0.1451	ZC3H12A/PTGS2/HSPB1/FGF2/PRKCA/VEGFA/PLK2/BMP4/CD40/SLIT2/RHOJ/ETS1/NR2F2/BMPR2/KLF4/THBS1/EDN1/BMPER/CARD10/RHOB/STARD13/MEOX2/AMOTL1/MEF2C/SIRT1/MIR19B2/WNT5A/MIR137/SPARC/PTPRM/SP100/GATA3/ABL1/ROCK2/PPARG/MIR199A2/ATOH8	37
BP	GO:0045638	negative regulation of myeloid cell differentiation	17/2306	91/18670	0.05231	0.1886	0.1451	NFKBIA/TRIB1/CDK6/MEIS1/MAFB/CCL3/ZFP36/UBASH3B/PRMT1/KLF13/FBN1/RBM15/MIR125B1/HOXA9/TLR3/PIAS3/ZNF675	17
BP	GO:0002548	monocyte chemotaxis	13/2306	65/18670	0.05236	0.1886	0.1451	CCL20/CCL5/IL6/CXCL10/CCL2/CCL8/CCL7/CCL3L3/SLIT2/CCL3/CCL1/SLAMF8/SERPINE1	13
BP	GO:0035308	negative regulation of protein dephosphorylation	13/2306	65/18670	0.05236	0.1886	0.1451	ENSA/PPP4R4/PPP1R15A/ROCK1/SET/PPP1R9B/PHACTR2/RGN/TNF/FKBP1A/ROCK2/PPP1R14C/SH3RF2	13
BP	GO:0048489	synaptic vesicle transport	26/2306	152/18670	0.05263	0.1893	0.1457	ADORA2A/STX3/BACE1/RAB3GAP1/LIN7A/CDK5/SNAP47/RAB3A/SYT4/ARF1/PREPL/PFN2/DGKI/ATP2A2/SNPH/STXBP1/SYT1/GRIN3A/TOR1A/AP3S1/NAPB/CNIH2/DVL1/P2RX7/PPFIA3/PICALM	26
BP	GO:0097480	establishment of synaptic vesicle localization	26/2306	152/18670	0.05263	0.1893	0.1457	ADORA2A/STX3/BACE1/RAB3GAP1/LIN7A/CDK5/SNAP47/RAB3A/SYT4/ARF1/PREPL/PFN2/DGKI/ATP2A2/SNPH/STXBP1/SYT1/GRIN3A/TOR1A/AP3S1/NAPB/CNIH2/DVL1/P2RX7/PPFIA3/PICALM	26
BP	GO:0010810	regulation of cell-substrate adhesion	35/2306	215/18670	0.05281	0.1894	0.1457	NINJ1/CDK6/CSF1/PDPN/CORO1C/VEGFA/ROCK1/COL1A1/PLAU/NEDD9/MYADM/LIMS2/GBP1/THBS1/CCDC80/RSU1/HAS2/DUSP3/PHLDB2/ARPC2/HSD17B12/TACSTD2/ACTN4/FZD4/COL16A1/SDC4/SERPINE1/ABL1/ROCK2/EPHA1/CDC42/FERMT1/ITGA6/FZD7/CRKL	35
BP	GO:0032388	positive regulation of intracellular transport	35/2306	215/18670	0.05281	0.1894	0.1457	ZC3H12A/PTGS2/IL1B/DAB2/PDCD5/PAK1/IL4R/FYN/SNX4/ANK3/RUFY3/PIK3R2/UBR5/TCF7L2/RDX/ARIH2/EHD1/RHOU/CEP290/CPSF6/CDK5/KCNB1/ARF1/BAP1/STXBP1/PRKCD/SYT1/CTDSPL2/GAS6/SCP2/VAMP7/NPPA/NEDD4/TMEM30B/CHP2	35
BP	GO:0070374	positive regulation of ERK1 and ERK2 cascade	35/2306	215/18670	0.05281	0.1894	0.1457	CCL20/BMP2/ICAM1/CCL5/RIPK2/CCL2/CCL8/CCL7/KIT/FGF2/PRKCA/CFLAR/BMP4/PDGFRB/CCL3L3/CD44/IL26/CCL3/BMPER/AKAP12/PDGFD/F2R/CCL1/TNFAIP8L3/HAVCR2/TNF/PDGFC/NPTN/ABL1/GAS6/PTPN11/FGF10/SERPINF2/CRKL/GLIPR2	35
BP	GO:0001910	regulation of leukocyte mediated cytotoxicity	15/2306	78/18670	0.05289	0.1894	0.1457	CXCL6/ICAM1/IL7R/HLA-E/IL12A/HLA-F/FADD/HLA-A/MICB/HAVCR2/HLA-G/NCR1/P2RX7/HLA-B/HLA-H	15
BP	GO:0042246	tissue regeneration	15/2306	78/18670	0.05289	0.1894	0.1457	NINJ1/CFLAR/YAP1/IFRD1/AKIRIN1/GSN/BIN3/NINJ2/PPP3CA/DUSP10/CDKN1A/FGF10/MIR199A2/IGF1/FZD7	15
BP	GO:0055021	regulation of cardiac muscle tissue growth	15/2306	78/18670	0.05289	0.1894	0.1457	FGF2/MEIS1/JARID2/PAK1/PIM1/EDN1/RGS2/GATA6/YAP1/MEF2C/MIR19B2/RGS4/MIR1-2/MIR199A2/IGF1	15
BP	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	15/2306	78/18670	0.05289	0.1894	0.1457	BDKRB2/CD44/DYRK2/E2F2/PMAIP1/HIPK2/BCL3/SIRT1/TP63/DDX5/TOPORS/UBB/CDKN1A/MYBBP1A/HINT1	15
BP	GO:2000300	regulation of synaptic vesicle exocytosis	15/2306	78/18670	0.05289	0.1894	0.1457	ADORA2A/BACE1/RAB3GAP1/CDK5/RAB3A/SYT4/PREPL/PFN2/DGKI/ATP2A2/STXBP1/SYT1/GRIN3A/NAPB/DVL1	15
BP	GO:0030832	regulation of actin filament length	30/2306	180/18670	0.05334	0.1908	0.1468	ICAM1/ARPC1A/DBN1/CDC42EP1/ARHGAP18/LIMA1/ACTR3/CDC42EP3/SLIT2/MYADM/ARHGAP28/FMN2/RDX/DSTN/PLEKHH2/ARPC2/CAPZA2/ARF6/ARF1/PFN2/EPS8/GSN/PRKCD/GMFB/MIR214/PDXP/ACTR2/TMOD2/PLEKHG2/MAGEL2	30
BP	GO:0042471	ear morphogenesis	21/2306	118/18670	0.05334	0.1908	0.1468	LRIG1/NTN1/MAFB/SIX1/INSIG2/ALDH1A3/TTC39C/EDN1/FZD2/CEP290/SIX4/WNT5A/PRKRA/PTK7/OSR2/ATP8A2/GATA3/FGF10/DVL1/OSR1/DVL2	21
BP	GO:0002446	neutrophil mediated immunity	74/2306	499/18670	0.0535	0.1911	0.147	CXCL1/CXCL6/OLR1/IL6/TNFAIP6/PLD1/NFKB1/ANPEP/PSMB7/PYGL/C3/TNFRSF1B/ROCK1/IRAK4/CNN2/CTSS/TOM1/VCL/FRMPD3/PLAU/CD44/CD58/FTH1/IDH1/AMPD3/CYBA/GLA/COMMD3/GSDMD/GLB1/SDCBP/SIRPA/METTL7A/PRG3/CAND1/DNAJC3/PPIA/IGF2R/MMP9/S100A11/CEP290/IMPDH2/CPNE3/CRISPLD2/ATG7/RAB3A/PAFAH1B2/RAB18/GSN/HMOX2/CEACAM3/DYNLL1/ACTR10/SERPINB1/GYG1/RAB9B/FRK/PTX3/DIAPH1/PRKCD/AGA/HBB/VAMP7/ACTR2/TBC1D10C/SERPINA3/GCA/CSTB/ALDOC/SERPINA1/RAB31/UBR4/HLA-H/ADAM8	74
BP	GO:0010975	regulation of neuron projection development	74/2306	499/18670	0.0535	0.1911	0.147	ZSWIM4/NTN1/ZFYVE27/DENND5A/SIPA1L1/DBN1/CAPRIN1/VEGFA/EEF2K/PLK2/CFLAR/PAK1/FZD1/MOV10/FYN/SLIT2/BMPR2/KLF4/RUFY3/NEUROG3/KIDINS220/CCDC88A/DPYSL3/SEMA4D/SDC2/RGS2/LPAR1/CHN1/HECW2/CARM1/IFRD1/ROBO1/MEF2C/ITPKA/ATF1/CDK5/WNT5A/ARF6/BHLHB9/SYT4/ARF1/PTK7/PDLIM5/YWHAH/BRSK2/FZD4/DLG4/ATP8A2/PLXND1/TMEM106B/GDI1/ASAP1/GATA3/SYT1/CRMP1/RTN4/PPP3CA/NPTN/ABL1/YTHDF1/VAMP7/ACTR2/SEMA4F/CDH4/ITGA6/DVL1/DVL2/MYCBP2/MYLIP/NEDD4/NGEF/ANKRD27/CRKL/SNX3	74
BP	GO:0009063	cellular amino acid catabolic process	22/2306	125/18670	0.05421	0.1935	0.1489	DDAH1/KYNU/GLS/IDO1/HIBCH/BCKDHB/IL4I1/FAH/ACAT1/GLUD1/PCYOX1/HNMT/AADAT/HIBADH/AMT/ALDH7A1/ABAT/ADO/DDAH2/ALDH5A1/ENOSF1/BCAT2	22
BP	GO:0001658	branching involved in ureteric bud morphogenesis	12/2306	59/18670	0.05445	0.1937	0.1491	BMP2/FGF2/SIX1/VEGFA/BMP4/PKD2/HOXA11/SIX4/PGF/TACSTD2/HOXB7/LGR4	12
BP	GO:0045843	negative regulation of striated muscle tissue development	12/2306	59/18670	0.05445	0.1937	0.1491	BMP2/MEIS1/JARID2/BMP4/PAK1/RGS2/SIX4/AKIRIN1/RGS4/MIR1-2/MIR199A2/FZD7	12
BP	GO:0046847	filopodium assembly	12/2306	59/18670	0.05445	0.1937	0.1491	FSCN1/FNBP1L/DPYSL3/PPP1R9B/FGD4/FGD1/ARF6/PRKCD/MYO10/RALA/CDC42/ITGA6	12
BP	GO:1902883	negative regulation of response to oxidative stress	12/2306	59/18670	0.05445	0.1937	0.1491	SOD2/GPR37L1/HSPB1/NCOA7/SLC7A11/FZD1/FYN/NME5/SIRT1/ATG7/TXN/OXR1	12
BP	GO:2000756	regulation of peptidyl-lysine acetylation	12/2306	59/18670	0.05445	0.1937	0.1491	IL1B/LIF/PPARGC1A/AUTS2/SET/SNAI2/RPS6KA4/SIRT1/GATA3/IWS1/SETD5/ZNF451	12
BP	GO:0051896	regulation of protein kinase B signaling	39/2306	244/18670	0.05445	0.1937	0.1491	KIT/FGF2/C1QTNF1/PIK3CD/EREG/PDGFRB/FYN/IRS1/IL26/KLF4/CCL3/THBS1/PIK3R2/TRIB3/TCF7L2/TGFA/HBEGF/MC1R/SESN3/AXL/SIRT1/TNFAIP8L3/RCN3/GDF15/TXN/MIR137/TNF/FGF5/IAPP/GATA3/HLA-G/RTN4/PPP2R5C/GAS6/PTPN11/ENG/FGF10/MIR199A2/ADAM8	39
BP	GO:0060047	heart contraction	44/2306	280/18670	0.05486	0.1951	0.1501	ZC3H12A/GPD1L/EPAS1/POPDC2/GSTO1/IRX5/CALM1/PDE4D/CAMK2D/HSPB7/GCH1/ADA/ACTC1/EDN1/DMPK/HBEGF/TRPC1/SGCD/TGFB2/RGS2/THRA/HCN4/ITPR2/RGS4/ADORA1/KCND1/CACNA1F/CACNA1B/SGCG/CALM2/ATP2A2/MIR1-2/STIM1/SNTA1/NPR2/PDE4B/KCND3/ATP1A4/MYH6/NPPA/PDE5A/SRI/CASQ1/ADORA3	44
BP	GO:0045930	negative regulation of mitotic cell cycle	52/2306	338/18670	0.05505	0.1956	0.1505	PSME2/CCL2/PSMA6/CDK6/PSMB10/BTG3/FHL1/PSMB8/PSMB7/PSME1/PLK2/BMP4/PSMB9/RPA2/PKD2/CCND1/KLF4/PSMA3/PRMT1/ZFP36L2/MAD1L1/CDC14B/GJC2/CARM1/PSMA1/PSMB2/CDKN2C/MIR19B2/NKX3-1/BCL2L1/BTG2/PSMB3/MIR137/ARID3A/TNF/CNOT8/PSMA8/ZNF830/CDK2AP2/ABL1/SETMAR/CTDSP2/ZFYVE19/CDKN1A/ANGEL2/PSME4/TFDP1/PSMB5/PSMG2/TAOK1/FOXO4/PSMF1	52
BP	GO:0033135	regulation of peptidyl-serine phosphorylation	24/2306	139/18670	0.05548	0.1963	0.151	PTGS2/IL6/LIF/RIPK2/BDKRB2/CNKSR3/GPD1L/VEGFA/PAK1/CD44/BCAR3/PDE4D/FNIP2/STK4/FNIP1/SMYD3/WNT5A/ARAF/MTCP1/PFN2/TXN/TNF/TRIM6/GAS6	24
BP	GO:0045580	regulation of T cell differentiation	24/2306	139/18670	0.05548	0.1963	0.151	NFKBIZ/ZC3H12A/CD83/RIPK2/SH3RF1/IRF1/TNFSF9/IL7R/BMP4/IL12A/MYB/IL4R/SOCS1/IL15/CYLD/ADA/GATA3/HLA-G/PRDM1/ABL1/DUSP10/SASH3/ADAM8/CBFB	24
BP	GO:0038034	signal transduction in absence of ligand	14/2306	72/18670	0.0555	0.1963	0.151	CSF2/IL1B/IL1A/PPP2R1B/BCL2L2/FYN/FADD/MKNK2/SNAI2/BCL2L1/TNF/FGF10/EYA2/SGK3	14
BP	GO:0051155	positive regulation of striated muscle cell differentiation	14/2306	72/18670	0.0555	0.1963	0.151	BMP4/IL4R/EDN1/CXCL9/MORF4L2/FLOT1/EHD1/MEF2C/MIR19B2/GDF15/MIR1-2/MIR199A2/IGF1/CAPN2	14
BP	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand	14/2306	72/18670	0.0555	0.1963	0.151	CSF2/IL1B/IL1A/PPP2R1B/BCL2L2/FYN/FADD/MKNK2/SNAI2/BCL2L1/TNF/FGF10/EYA2/SGK3	14
BP	GO:0009067	aspartate family amino acid biosynthetic process	6/2306	23/18670	0.05578	0.1963	0.151	MTHFD2L/PLOD2/MTR/BHMT2/ASNS/MTAP	6
BP	GO:0009226	nucleotide-sugar biosynthetic process	6/2306	23/18670	0.05578	0.1963	0.151	GFPT2/UGP2/NAGK/GMDS/GMPPB/PGM3	6
BP	GO:0010528	regulation of transposition	6/2306	23/18670	0.05578	0.1963	0.151	APOBEC3G/MOV10/MYBL1/APOBEC3H/ZNF91/APOBEC3F	6
BP	GO:0010529	negative regulation of transposition	6/2306	23/18670	0.05578	0.1963	0.151	APOBEC3G/MOV10/MYBL1/APOBEC3H/ZNF91/APOBEC3F	6
BP	GO:0032703	negative regulation of interleukin-2 production	6/2306	23/18670	0.05578	0.1963	0.151	TNFAIP3/GBP1/ZFP36/HAVCR2/GATA3/HOMER2	6
BP	GO:0032753	positive regulation of interleukin-4 production	6/2306	23/18670	0.05578	0.1963	0.151	IL33/CEBPB/HLA-E/HAVCR2/GATA3/SASH3	6
BP	GO:0042451	purine nucleoside biosynthetic process	6/2306	23/18670	0.05578	0.1963	0.151	ADA/NME5/IMPDH2/GUK1/MTAP/PRTFDC1	6
BP	GO:0042454	ribonucleoside catabolic process	6/2306	23/18670	0.05578	0.1963	0.151	APOBEC3G/NUDT18/ADA/APOBEC3H/CDADC1/APOBEC3F	6
BP	GO:0046129	purine ribonucleoside biosynthetic process	6/2306	23/18670	0.05578	0.1963	0.151	ADA/NME5/IMPDH2/GUK1/MTAP/PRTFDC1	6
BP	GO:0060479	lung cell differentiation	6/2306	23/18670	0.05578	0.1963	0.151	KLF2/GATA6/THRA/YAP1/FGF10/NFIB	6
BP	GO:1901889	negative regulation of cell junction assembly	6/2306	23/18670	0.05578	0.1963	0.151	CORO1C/ROCK1/THBS1/PHLDB2/TNF/ROCK2	6
BP	GO:2000726	negative regulation of cardiac muscle cell differentiation	6/2306	23/18670	0.05578	0.1963	0.151	BMP2/PAK1/RGS2/RGS4/MIR199A2/FZD7	6
BP	GO:0051384	response to glucocorticoid	25/2306	146/18670	0.05592	0.1967	0.1513	ICAM1/PTGS2/IL6/CLDN1/FOXO1/CFLAR/SLIT2/CCND1/ZFP36/EDN1/SRD5A1/GLB1/ZFP36L2/HNMT/SMYD3/ERRFI1/GJB2/ABCC2/TNF/BGLAP/ASS1/SPARC/PAPPA/CPS1/CDKN1A	25
BP	GO:0051701	interaction with host	34/2306	209/18670	0.05608	0.1971	0.1517	ZC3H12A/ICAM1/TNIP1/CLDN1/CCL8/ANPEP/XPR1/IFITM1/TNFRSF14/SLC20A2/IFIT1/TRIM25/EPS15/RXRA/ITGB5/CHMP4B/ITCH/EIF2AK4/HIPK2/ITGA2/PPIA/KPNA3/AXL/ATG7/TRIM21/BCL2L1/GSN/PTX3/ZNF639/GAS6/KPNA2/TRIM38/NEDD4/SNX3	34
BP	GO:0006401	RNA catabolic process	60/2306	397/18670	0.05624	0.1976	0.152	ZC3H12A/PSME2/PSMA6/ERN1/ISG20/HSPB1/PSMB10/PSMB8/PRKCA/PSMB7/PSME1/TNFRSF1B/ROCK1/TTC37/PSMB9/SET/MOV10/OAS2/FTO/PSMA3/RPS3A/ZFP36/EXOSC6/ZFP36L2/CSDC2/HNRNPA0/RPL7/RPL22/PDE12/DCP1A/PSMA1/PSMB2/DEDD2/PABPC1/RPL37A/DIS3L/BTG2/SERBP1/SAMD4B/PSMB3/DDX5/EIF3E/RNH1/CNOT8/SYNCRIP/RPL15/PRKCD/FEN1/PSMA8/FASTKD3/ROCK2/FXR2/UBB/LSM6/PATL1/ANGEL2/PSME4/PSMB5/PSMF1/RPS18	60
BP	GO:0000186	activation of MAPKK activity	11/2306	53/18670	0.05637	0.1979	0.1523	MAP3K8/RIPK2/BMP4/KIDINS220/MAP3K1/F2R/ADORA1/MAP3K2/MLKL/TAOK1/CRKL	11
BP	GO:1903510	mucopolysaccharide metabolic process	20/2306	112/18670	0.05657	0.1985	0.1528	IL1B/ST3GAL1/NFKB1/FGF2/B4GALT3/CD44/VCAN/CHST7/IL15/PIM1/GLB1/CLTC/CSGALNACT1/HAS2/CSGALNACT2/ITIH1/HAS1/HAS3/ST3GAL3/ST3GAL4	20
BP	GO:0048015	phosphatidylinositol-mediated signaling	30/2306	181/18670	0.05667	0.1988	0.1529	CCL5/IER3/KIT/NPR3/PIK3CD/FBXL2/PLCE1/PDGFRB/FYN/IRS1/KLF4/PIK3R2/PTPN13/EDN1/SEMA4D/PDGFD/F2R/TGFB2/SIRT1/NKX3-1/GSN/TNF/PEAR1/PDGFC/GATA3/PPP2R5C/PIP4K2A/IGF1/NEDD4/PRR5	30
BP	GO:0010948	negative regulation of cell cycle process	55/2306	361/18670	0.05774	0.2024	0.1557	PSME2/LIF/CCL2/PSMA6/CDK6/PSMB10/FHL1/PSMB8/PSMB7/PSME1/PLK2/BMP4/PSMB9/RPA2/PKD2/CCND1/KLF4/PSMA3/TRIM37/PRMT1/ZFP36L2/MAD1L1/CDC14B/GJC2/KAT2B/CARM1/PSMA1/PSMB2/CDKN2C/MIR19B2/E2F6/BTG2/PSMB3/MIR137/ARID3A/CNOT8/PSMA8/ZNF830/HLA-G/CDK2AP2/SETMAR/MAX/CTDSP2/ZFYVE19/CDKN1A/FGF10/PSME4/TFDP1/PSMB5/PSMG2/TAOK1/UIMC1/PHC3/FOXO4/PSMF1	55
BP	GO:0051048	negative regulation of secretion	38/2306	238/18670	0.05777	0.2024	0.1557	ZC3H12A/TNFAIP3/IL1B/LIF/IL33/RSAD2/TNFRSF1B/HLA-F/PNKD/LRRC32/IRS1/GBP1/OXTR/ADA/RHBDF2/EDN1/HADH/INHBB/F2R/SERGEF/SRGN/ADORA1/KCNB1/ANXA4/SYT4/SLC30A1/ABAT/TNF/SYTL4/SERPINB1/PPP3CA/LGR4/RAB11FIP1/GAS6/PTPN11/PYDC2/MAPKBP1/ADRA2A	38
BP	GO:0045646	regulation of erythrocyte differentiation	10/2306	47/18670	0.05799	0.2028	0.156	ID2/CDK6/ISG15/MAFB/STAT1/ETS1/ZFP36/PRMT1/KLF13/STAT3	10
BP	GO:0050435	amyloid-beta metabolic process	10/2306	47/18670	0.05799	0.2028	0.156	IFNGR1/BACE2/ROCK1/BACE1/PSENEN/TNF/ROCK2/TMED10/IGF1/PICALM	10
BP	GO:1901659	glycosyl compound biosynthetic process	10/2306	47/18670	0.05799	0.2028	0.156	TYMP/ADA/NME5/IMPDH2/GUK1/LCMT2/MTAP/PRTFDC1/TK2/DCK	10
BP	GO:0006687	glycosphingolipid metabolic process	13/2306	66/18670	0.05813	0.2028	0.156	KIT/ST8SIA1/ESYT1/B4GALT3/UGCG/A4GALT/NAGA/GLA/GLB1/ITGB8/UGT8/ALDH5A1/PRKCD	13
BP	GO:0046888	negative regulation of hormone secretion	13/2306	66/18670	0.05813	0.2028	0.156	IL1B/LIF/IRS1/EDN1/HADH/INHBB/ADORA1/KCNB1/SYTL4/PPP3CA/RAB11FIP1/PTPN11/ADRA2A	13
BP	GO:0051785	positive regulation of nuclear division	13/2306	66/18670	0.05813	0.2028	0.156	IL1B/IL1A/EREG/PDGFRB/MSX2/EDN1/TGFA/LRP5/NSMCE2/WNT5A/SH2B1/IGF1/NPM2	13
BP	GO:1904888	cranial skeletal system development	13/2306	66/18670	0.05813	0.2028	0.156	RAB23/SIX1/INSIG2/BMP4/IRX5/RDH10/MSX2/TGFB2/SIX4/MEF2C/TP63/SH3PXD2B/CRKL	13
BP	GO:0006446	regulation of translational initiation	15/2306	79/18670	0.05814	0.2028	0.156	CCL5/HSPB1/EIF4A2/PPP1R15A/RXRA/EIF2AK4/EIF4G3/DNAJC3/EIF1/DHX29/EIF3E/TNF/EIF2B5/YTHDF1/EIF1B	15
BP	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	7/2306	29/18670	0.05866	0.2034	0.1565	CITED2/DAB2/THBS1/SDCBP/HIPK2/CDKN1C/FERMT1	7
BP	GO:0033032	regulation of myeloid cell apoptotic process	7/2306	29/18670	0.05866	0.2034	0.1565	CCL5/PIK3CD/SLC7A11/IRF7/THRA/MEF2C/SIRT1	7
BP	GO:0044788	modulation by host of viral process	7/2306	29/18670	0.05866	0.2034	0.1565	ZC3H12A/CCL8/FBXL2/EIF2AK4/IGF2R/PTX3/NUCKS1	7
BP	GO:0045980	negative regulation of nucleotide metabolic process	7/2306	29/18670	0.05866	0.2034	0.1565	PID1/PPARGC1A/PPIF/PDE12/DNAJC15/STAT3/SIRT6	7
BP	GO:0120033	negative regulation of plasma membrane bounded cell projection assembly	7/2306	29/18670	0.05866	0.2034	0.1565	SLIT2/TCHP/EVI5L/PFN2/TACSTD2/PRKCD/MIR214	7
BP	GO:1900027	regulation of ruffle assembly	7/2306	29/18670	0.05866	0.2034	0.1565	ICAM1/CORO1C/RDX/PFN2/EPS8/TACSTD2/SH3YL1	7
BP	GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus	7/2306	29/18670	0.05866	0.2034	0.1565	CITED2/DAB2/THBS1/SDCBP/HIPK2/CDKN1C/FERMT1	7
BP	GO:1990126	retrograde transport, endosome to plasma membrane	7/2306	29/18670	0.05866	0.2034	0.1565	ANKRD50/MICALL1/VPS35/CCDC93/GRIPAP1/ANKRD27/VPS26A	7
BP	GO:2000171	negative regulation of dendrite development	7/2306	29/18670	0.05866	0.2034	0.1565	PLK2/CARM1/ARF6/YWHAH/ASAP1/PPP3CA/NGEF	7
BP	GO:2000727	positive regulation of cardiac muscle cell differentiation	7/2306	29/18670	0.05866	0.2034	0.1565	BMP4/EDN1/MEF2C/MIR19B2/MIR1-2/MIR199A2/IGF1	7
BP	GO:0042770	signal transduction in response to DNA damage	23/2306	133/18670	0.05895	0.2042	0.1571	BID/PLK2/CD44/PRMT1/PMAIP1/HIPK2/CDC14B/SNAI2/CARM1/BCL3/SIRT1/BTG2/SESN2/DDX5/ARID3A/PPM1D/CNOT8/SP100/ABL1/CDKN1A/TFDP1/CEP63/UIMC1	23
BP	GO:0030890	positive regulation of B cell proliferation	9/2306	41/18670	0.05914	0.2042	0.1571	TNFSF13B/CD40/SLC39A10/ADA/CLCF1/MEF2C/CDKN1A/TICAM1/SASH3	9
BP	GO:0042572	retinol metabolic process	9/2306	41/18670	0.05914	0.2042	0.1571	AKR1B1/ALDH1A3/CYP27C1/RDH10/RDH8/DHRS3/CYP1A2/RDH13/ADH1C	9
BP	GO:0044743	protein transmembrane import into intracellular organelle	9/2306	41/18670	0.05914	0.2042	0.1571	DNAJC19/DNAJC15/GRPEL1/GRPEL2/LONP2/PEX1/CHCHD4/PEX26/TIMM17B	9
BP	GO:0045616	regulation of keratinocyte differentiation	9/2306	41/18670	0.05914	0.2042	0.1571	ROCK1/ZFP36/MSX2/CYP27B1/ERRFI1/VDR/TP63/ROCK2/CBFB	9
BP	GO:0097178	ruffle assembly	9/2306	41/18670	0.05914	0.2042	0.1571	ICAM1/CORO1C/RDX/ARF6/PFN2/EPS8/TACSTD2/SH3YL1/SNX10	9
BP	GO:1903170	negative regulation of calcium ion transmembrane transport	9/2306	41/18670	0.05914	0.2042	0.1571	GSTO1/RRAD/CALM1/PKD2/THADA/GEM/CALM2/SRI/ADRA2A	9
BP	GO:1905209	positive regulation of cardiocyte differentiation	9/2306	41/18670	0.05914	0.2042	0.1571	BMP4/EDN1/TGFB2/GATA6/MEF2C/MIR19B2/MIR1-2/MIR199A2/IGF1	9
BP	GO:0001837	epithelial to mesenchymal transition	24/2306	140/18670	0.05943	0.2047	0.1575	BMP2/IL6/IL1B/DAB2/PDPN/BMP4/WWTR1/COL1A1/MSX2/SDCBP/TGFB2/PHLDB1/SPRY1/SNAI2/HAS2/PHLDB2/DACT3/WNT5A/DDX5/RTN4/ENG/SDHAF2/AKNA/GLIPR2	24
BP	GO:0000266	mitochondrial fission	8/2306	35/18670	0.05952	0.2047	0.1575	MX1/PPARGC1A/MX2/MTFR1/STAT2/TMEM135/VPS35/GGNBP1	8
BP	GO:0015695	organic cation transport	8/2306	35/18670	0.05952	0.2047	0.1575	ADORA2A/SLC22A2/SLC22A1/SLC38A2/SLC22A4/SLC25A20/RALBP1/SLC22A3	8
BP	GO:0033363	secretory granule organization	8/2306	35/18670	0.05952	0.2047	0.1575	ABCA1/RAB38/F2R/SRGN/SYT4/CCDC136/ZPBP2/RFX2	8
BP	GO:0042092	type 2 immune response	8/2306	35/18670	0.05952	0.2047	0.1575	IL6/IL33/RSAD2/IDO1/IL4R/STAT6/BCL3/GATA3	8
BP	GO:0051954	positive regulation of amine transport	8/2306	35/18670	0.05952	0.2047	0.1575	ADORA2A/OXTR/RAB3GAP1/KCNB1/SYT4/ABAT/STXBP1/P2RX7	8
BP	GO:1902991	regulation of amyloid precursor protein catabolic process	8/2306	35/18670	0.05952	0.2047	0.1575	IFNGR1/ROCK1/TNF/FKBP1A/ROCK2/TMED10/IGF1/PICALM	8
BP	GO:0046165	alcohol biosynthetic process	29/2306	175/18670	0.06023	0.207	0.1592	BMP2/AKR1B1/IL1B/NFKB1/PLCD3/FGF2/PLCE1/PLCD1/INSIG2/ACACB/SCD/GCH1/CYP27B1/TM7SF2/ACAT2/ACACA/IMPA2/MOXD1/NPC1L1/PLCB4/ITPKA/VDR/ACAA2/TNF/HSD17B7/GPAM/IDI1/IP6K3/PTS	29
BP	GO:1990138	neuron projection extension	28/2306	168/18670	0.06025	0.207	0.1592	NTN1/ZFYVE27/DBN1/AUTS2/VEGFA/PAK1/VCL/SLIT2/BMPR2/RUFY3/ITGA4/EIF2AK4/SEMA4D/IFRD1/CDK5/WNT5A/SYT4/FLRT3/GDI1/SYT1/RTN4/ABL1/SEMA4F/CDH4/DVL1/TMEM108/RAPH1/USP9X	28
BP	GO:0042058	regulation of epidermal growth factor receptor signaling pathway	16/2306	86/18670	0.06033	0.2071	0.1594	ITGA1/GPRC5A/EREG/EPS15/RHBDF2/TGFA/HBEGF/SPRY1/ERRFI1/MMP9/DUSP3/ADORA1/CDC42/CBLB/RNF126/ADRA2A	16
BP	GO:0006874	cellular calcium ion homeostasis	68/2306	458/18670	0.06068	0.2082	0.1602	BDKRB1/CCL5/S1PR3/CXCL10/BDKRB2/CCL8/CCL7/FGF2/C1QTNF1/PLCE1/GSTO1/PTGFR/CMKLR1/CD40/FYN/CALM1/HERPUD1/PDE4D/CAMK2D/PKD2/CXCL11/CCL3/CYBA/UBASH3B/OXTR/EDN1/PTGER2/CXCL9/DMPK/THADA/TRPC1/F2R/CCL1/GRINA/LPAR1/TMEM64/GNA13/SYPL2/ITPR2/VDR/CDK5/WNT5A/ATP13A3/ADORA1/TPCN1/RGN/SLC30A1/P2RX3/CALM2/ATP2A2/MIR1-2/DLG4/STIM1/FKBP1A/IAPP/DIAPH1/NPTN/ABL1/IMMT/MCOLN1/NMUR2/ATP13A2/MIR199A2/CCR10/SRI/P2RX7/CASQ1/TMEM165	68
BP	GO:0002294	CD4-positive, alpha-beta T cell differentiation involved in immune response	12/2306	60/18670	0.06073	0.2082	0.1602	NFKBIZ/ZC3H12A/IL6/RELB/RIPK2/IL18R1/MYB/IL4R/STAT6/BCL3/GATA3/STAT3	12
BP	GO:0048635	negative regulation of muscle organ development	12/2306	60/18670	0.06073	0.2082	0.1602	BMP2/MEIS1/JARID2/BMP4/PAK1/RGS2/SIX4/AKIRIN1/RGS4/MIR1-2/MIR199A2/FZD7	12
BP	GO:1901983	regulation of protein acetylation	14/2306	73/18670	0.06119	0.2096	0.1613	IL1B/LIF/PPARGC1A/AUTS2/SET/ARNTL/SNAI2/RPS6KA4/SIRT1/GATA3/IWS1/SETD5/TAOK1/ZNF451	14
BP	GO:0007160	cell-matrix adhesion	36/2306	225/18670	0.06177	0.2107	0.1621	VCAM1/ITGA1/NINJ1/CDK6/CSF1/CORO1C/VEGFA/ROCK1/JAM3/VCL/PPFIA1/PLAU/CD44/ITGB5/MKLN1/ITGA4/THBS1/TRIP6/ITGA2/DUSP3/NID2/PHLDB2/CDK5/ITGA11/HOXD3/FERMT2/COL16A1/SDC4/ZYX/SERPINE1/ABL1/ROCK2/EPHA1/FERMT1/ITGA6/ITGBL1	36
BP	GO:0001911	negative regulation of leukocyte mediated cytotoxicity	5/2306	18/18670	0.06185	0.2107	0.1621	IL7R/HLA-E/HLA-F/HAVCR2/HLA-G	5
BP	GO:0007221	positive regulation of transcription of Notch receptor target	5/2306	18/18670	0.06185	0.2107	0.1621	STAT1/WWC1/KAT2B/RBM15/PLXND1	5
BP	GO:0007250	activation of NF-kappaB-inducing kinase activity	5/2306	18/18670	0.06185	0.2107	0.1621	ZFP91/CARD10/TRAF2/TNFRSF10B/TLR3	5
BP	GO:0010713	negative regulation of collagen metabolic process	5/2306	18/18670	0.06185	0.2107	0.1621	IL6/ERRFI1/CYGB/PPARG/MIR218-1	5
BP	GO:0031998	regulation of fatty acid beta-oxidation	5/2306	18/18670	0.06185	0.2107	0.1621	ACACB/IRS1/CPT1A/ABCD1/LONP2	5
BP	GO:0072574	hepatocyte proliferation	5/2306	18/18670	0.06185	0.2107	0.1621	TNFAIP3/CEBPB/CFLAR/LIMS2/SULF2	5
BP	GO:0072575	epithelial cell proliferation involved in liver morphogenesis	5/2306	18/18670	0.06185	0.2107	0.1621	TNFAIP3/CEBPB/CFLAR/LIMS2/SULF2	5
BP	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	5/2306	18/18670	0.06185	0.2107	0.1621	SIX1/VEGFA/SIX4/HOXB7/LGR4	5
BP	GO:0150078	positive regulation of neuroinflammatory response	5/2306	18/18670	0.06185	0.2107	0.1621	IL6/IL1B/IL33/CCL3/TNF	5
BP	GO:0003014	renal system process	21/2306	120/18670	0.06196	0.211	0.1623	AKR1B1/ADORA2A/NPR3/KLHL3/BMP4/CYBA/SULF2/EDN1/MYO1E/F2R/ADCY7/RAB11FIP2/ADCY9/HAS2/ADCY3/ADORA1/SULF1/GSN/HBB/GAS6/SERPINF2	21
BP	GO:0007589	body fluid secretion	17/2306	93/18670	0.06215	0.2112	0.1625	KCNN4/NPR3/SLC22A2/VEGFA/HK2/SLC22A4/OAS2/CCND1/CYBA/OXTR/ADA/EDN1/VDR/ADORA1/SOCS2/NCOR2/FGF10	17
BP	GO:0035249	synaptic transmission, glutamatergic	17/2306	93/18670	0.06215	0.2112	0.1625	PTGS2/CCL2/ADORA2A/OXTR/RAB3GAP1/MEF2C/CDK5/ADORA1/DGKI/TNF/STXBP1/TSHZ3/GRM2/SYT1/GRIK4/NAPB/CNIH2	17
BP	GO:0036473	cell death in response to oxidative stress	17/2306	93/18670	0.06215	0.2112	0.1625	SOD2/GPR37L1/HSPB1/MMP3/NCOA7/SLC7A11/FZD1/LANCL1/FYN/ARL6IP5/NME5/SIRT1/ATG7/TXN/PRKCD/OXR1/SIGMAR1	17
BP	GO:1901184	regulation of ERBB signaling pathway	17/2306	93/18670	0.06215	0.2112	0.1625	ITGA1/GPRC5A/EREG/EPS15/RHBDF2/TGFA/HBEGF/SPRY1/ERRFI1/MMP9/DUSP3/ADORA1/RTN4/CDC42/CBLB/RNF126/ADRA2A	17
BP	GO:0035270	endocrine system development	22/2306	127/18670	0.06265	0.2127	0.1637	BMP2/IL6/CDK6/PITX1/CITED2/ARID5B/SIX1/FOXO1/GIP/BMP4/ETS1/NEUROG3/SRD5A1/ARNTL/GATA6/THRA/WNT5A/CDKN1C/HOXD3/GATA3/FGF10/CRKL	22
BP	GO:0031396	regulation of protein ubiquitination	33/2306	204/18670	0.06296	0.2137	0.1644	BIRC3/TNFAIP3/RIPK2/BAG2/BIRC2/ISG15/DAXX/PRR7/DNAJA1/RNF20/FYN/HERPUD1/NDFIP1/TRIB3/UBR5/CDC14B/ARRDC4/CDK5/ARRDC3/DCUN1D4/UBXN1/TOPORS/PRMT3/IVNS1ABP/FKBP1A/ABL1/BCL10/UBB/NDFIP2/TICAM1/SH3RF2/MYCBP2/UBE2S	33
BP	GO:0032409	regulation of transporter activity	44/2306	283/18670	0.06322	0.2142	0.1648	CCL2/PPARGC1A/FHL1/CNKSR3/GPD1L/DAPK1/CTSS/GSTO1/RRAD/PPIF/CALM1/PDE4D/CAMK2D/PKD2/ANK3/NDFIP1/COX17/THADA/GRIA3/HECW2/MMP9/MEF2C/GEM/STAC/RGN/ACTB/YWHAH/CALM2/ACTN4/MIR1-2/DLG4/STIM1/FKBP1A/PRKCD/PDE4B/PPARG/NDFIP2/NPPA/CNIH2/OSR1/SRI/CASQ1/NEDD4/ADRA2A	44
BP	GO:0009066	aspartate family amino acid metabolic process	11/2306	54/18670	0.06322	0.2142	0.1648	MTHFD2L/AADAT/PLOD2/ALDH7A1/MTR/ASS1/BHMT2/ASNS/PHGDH/MTAP/GNMT	11
BP	GO:0051353	positive regulation of oxidoreductase activity	11/2306	54/18670	0.06322	0.2142	0.1648	IL1B/NPR3/CYBA/GCH1/EDN1/CYP27B1/COX17/VDR/RGN/TNF/ABL1	11
BP	GO:0055024	regulation of cardiac muscle tissue development	18/2306	100/18670	0.06365	0.2155	0.1658	BMP2/FGF2/MEIS1/JARID2/BMP4/PAK1/PIM1/EDN1/RGS2/GATA6/YAP1/MEF2C/MIR19B2/RGS4/MIR1-2/MIR199A2/IGF1/FZD7	18
BP	GO:0051494	negative regulation of cytoskeleton organization	25/2306	148/18670	0.06385	0.216	0.1662	MID1/PPFIA1/LIMA1/SLIT2/MYADM/TRIM37/ARHGAP28/RDX/KAT2B/PLEKHH2/CLIP3/PHLDB2/CAPZA2/PFN2/EPS8/GSN/TACSTD2/PRKCD/GMFB/MIR214/TMOD2/TAOK1/MID1IP1/CAMSAP1/WASF2	25
BP	GO:0061041	regulation of wound healing	25/2306	148/18670	0.06385	0.216	0.1662	TNFAIP3/SERPINB2/FGF2/C1QTNF1/PRKCA/PDPN/PLAU/THBS1/UBASH3B/EDN1/HBEGF/F2R/PHLDB2/RAB3A/MYLK/ABAT/SYTL4/PRKCD/SERPINE1/DUSP10/CDKN1A/MYH9/MIR199A2/SERPINF2/ADRA2A	25
BP	GO:1903707	negative regulation of hemopoiesis	26/2306	155/18670	0.064	0.2164	0.1665	NFKBIA/ZC3H12A/ID2/TRIB1/CDK6/IRF1/MEIS1/MAFB/BMP4/IL4R/SOCS1/CCL3/ZFP36/UBASH3B/PRMT1/KLF13/HES5/FBN1/RBM15/MIR125B1/HOXA9/TLR3/HLA-G/PIAS3/ZNF675/CBFB	26
BP	GO:0045666	positive regulation of neuron differentiation	56/2306	371/18670	0.06441	0.2175	0.1674	BMP2/GDPD5/NTN1/ZFYVE27/DBN1/CAPRIN1/VEGFA/EEF2K/CFLAR/BMP4/PAK1/FZD1/TCF12/FYN/SLIT2/IRX3/BMPR2/RUFY3/NEUROG3/BEND6/KIDINS220/DPYSL3/SEMA4D/RGS2/LPAR1/CSNK1E/GDF5/ROBO1/MEF2C/ITPKA/ATF1/WNT5A/BHLHB9/SYT4/ARF1/MIR137/PTK7/HOXD3/FZD4/DLG4/ATP8A2/PLXND1/SOCS2/TMEM106B/GDI1/SYT1/NPTN/VAMP7/ACTR2/GDF6/CDH4/ITGA6/DVL1/DVL2/ANKRD27/SNX3	56
BP	GO:0006644	phospholipid metabolic process	64/2306	430/18670	0.06441	0.2175	0.1674	PLD1/OSBPL10/KIT/LPIN1/FGF2/PIK3CD/GPD1L/PLCD1/PLSCR1/PLA2G4A/PDGFRB/SOCS1/SOCS3/RAB38/FABP3/PISD/PLA2G4C/IRS1/PIGV/KLF4/IDH1/DBI/PIK3R2/PTPN13/LIPG/PIK3R3/IMPA2/GATA6/RAB4A/PLEKHA3/CPNE3/EFR3A/PLA2G12A/TNFAIP8L3/ARF1/OSBPL5/ARF3/CLN8/ABHD5/SOCS2/ALDH5A1/ABHD3/GPAM/MPPE1/PRKCD/INPP5B/SGMS2/WDR91/PIGK/PIGS/CHKB/IDI1/IP6K3/PIP4K2A/FAR1/INPP1/PI4K2B/SH3YL1/SAMD8/SBF1/PLEKHA4/CAPN2/LCLAT1/STARD7	64
BP	GO:0009165	nucleotide biosynthetic process	58/2306	386/18670	0.06515	0.2199	0.1692	NAMPT/PTGS2/PID1/PRPS1/PPARGC1A/SLC2A6/KYNU/MTHFD2L/IDO1/HK2/PRPS1L1/ACACB/ELOVL5/ENO2/ADPGK/CMPK2/NUP133/AK1/SCD/ELOVL7/AMPD3/PGM2L1/ADA/ACAT1/NNMT/PPT1/ADCY7/ACACA/NME5/ACSL5/CBR4/ADCY9/ADCY3/ELOVL2/PARP9/IMPDH2/PPCS/HSD17B12/CDADC1/PDHB/PAPSS1/GUK1/GPAM/ME1/PGAM4/NPR2/PDK3/TK2/NPPA/NUP35/DCK/IGF1/STAT3/ALDOC/P2RX7/SIRT6/ELOVL3/LCLAT1	58
BP	GO:0002762	negative regulation of myeloid leukocyte differentiation	10/2306	48/18670	0.06549	0.2202	0.1694	TRIB1/CDK6/MAFB/CCL3/UBASH3B/FBN1/MIR125B1/TLR3/PIAS3/ZNF675	10
BP	GO:0044764	multi-organism cellular process	10/2306	48/18670	0.06549	0.2202	0.1694	BIRC3/IFIH1/BIRC2/DDX60/IRF7/TSPAN6/DDX58/DHX58/PPIA/GAS6	10
BP	GO:0046850	regulation of bone remodeling	10/2306	48/18670	0.06549	0.2202	0.1694	TNFAIP3/IL6/PRKCA/UBASH3B/TMEM64/BGLAP/IAPP/TNFRSF11B/P2RX7/ADAM8	10
BP	GO:0051150	regulation of smooth muscle cell differentiation	10/2306	48/18670	0.06549	0.2202	0.1694	SOD2/KIT/EREG/BMP4/SMARCD3/SIRT1/MIR1-2/MIR125B1/ENG/FOXO4	10
BP	GO:0061014	positive regulation of mRNA catabolic process	10/2306	48/18670	0.06549	0.2202	0.1694	ZC3H12A/ROCK1/MOV10/FTO/ZFP36/ZFP36L2/PABPC1/BTG2/CNOT8/ROCK2	10
BP	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	16/2306	87/18670	0.06581	0.2202	0.1694	CCL5/KIT/PIK3CD/PDGFRB/FYN/SEMA4D/PDGFD/F2R/TGFB2/SIRT1/NKX3-1/TNF/PDGFC/IGF1/NEDD4/PRR5	16
BP	GO:0072522	purine-containing compound biosynthetic process	48/2306	313/18670	0.06594	0.2202	0.1694	PID1/PRPS1/PPARGC1A/SLC2A6/MTHFD2L/HK2/PRPS1L1/ACACB/ELOVL5/ENO2/ADPGK/NUP133/AK1/SCD/ELOVL7/AMPD3/PGM2L1/ADA/ACAT1/PPT1/ADCY7/ACACA/NME5/ACSL5/CBR4/ADCY9/ADCY3/ELOVL2/IMPDH2/PPCS/HSD17B12/PDHB/PAPSS1/GUK1/MTAP/PRTFDC1/PGAM4/NPR2/PDK3/NPPA/NUP35/DCK/IGF1/STAT3/ALDOC/P2RX7/SIRT6/ELOVL3	48
BP	GO:0005513	detection of calcium ion	4/2306	13/18670	0.06642	0.2202	0.1694	CALM1/CALM2/STIM1/SYT1	4
BP	GO:0006012	galactose metabolic process	4/2306	13/18670	0.06642	0.2202	0.1694	PPARGC1A/GALM/PGM2L1/GLB1	4
BP	GO:0009162	deoxyribonucleoside monophosphate metabolic process	4/2306	13/18670	0.06642	0.2202	0.1694	CDADC1/GUK1/TK2/DCK	4
BP	GO:0009437	carnitine metabolic process	4/2306	13/18670	0.06642	0.2202	0.1694	SLC22A4/CROT/CPT1A/ACADM	4
BP	GO:0009650	UV protection	4/2306	13/18670	0.06642	0.2202	0.1694	SCARA3/MC1R/ERCC2/FEN1	4
BP	GO:0010745	negative regulation of macrophage derived foam cell differentiation	4/2306	13/18670	0.06642	0.2202	0.1694	NFKBIA/ABCA1/ABCA5/PPARG	4
BP	GO:0031274	positive regulation of pseudopodium assembly	4/2306	13/18670	0.06642	0.2202	0.1694	KIT/CDC42EP1/CDC42EP3/CDC42	4
BP	GO:0032530	regulation of microvillus organization	4/2306	13/18670	0.06642	0.2202	0.1694	PLD1/FSCN1/ATP8B1/PODXL	4
BP	GO:0032754	positive regulation of interleukin-5 production	4/2306	13/18670	0.06642	0.2202	0.1694	IL33/PDE4D/IL17RB/GATA3	4
BP	GO:0032823	regulation of natural killer cell differentiation	4/2306	13/18670	0.06642	0.2202	0.1694	IL15/AXL/PRDM1/GAS6	4
BP	GO:0042415	norepinephrine metabolic process	4/2306	13/18670	0.06642	0.2202	0.1694	AKR1B1/EPAS1/MOXD1/GATA3	4
BP	GO:0042761	very long-chain fatty acid biosynthetic process	4/2306	13/18670	0.06642	0.2202	0.1694	ELOVL5/ELOVL7/ELOVL2/ELOVL3	4
BP	GO:0043116	negative regulation of vascular permeability	4/2306	13/18670	0.06642	0.2202	0.1694	ADORA2A/DDAH1/SLIT2/AKAP12	4
BP	GO:0045602	negative regulation of endothelial cell differentiation	4/2306	13/18670	0.06642	0.2202	0.1694	S1PR3/VEGFA/FOXJ2/MIR1-2	4
BP	GO:0048715	negative regulation of oligodendrocyte differentiation	4/2306	13/18670	0.06642	0.2202	0.1694	ID2/DAAM2/HES5/DUSP10	4
BP	GO:0048875	chemical homeostasis within a tissue	4/2306	13/18670	0.06642	0.2202	0.1694	EPAS1/VEGFA/RCN3/HOMER2	4
BP	GO:0050713	negative regulation of interleukin-1 beta secretion	4/2306	13/18670	0.06642	0.2202	0.1694	ZC3H12A/TNFAIP3/SERPINB1/PYDC2	4
BP	GO:0060576	intestinal epithelial cell development	4/2306	13/18670	0.06642	0.2202	0.1694	YIPF6/C1GALT1/PRDM1/CDKN1A	4
BP	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development	4/2306	13/18670	0.06642	0.2202	0.1694	PAK1/RGS2/RGS4/MIR199A2	4
BP	GO:0070986	left/right axis specification	4/2306	13/18670	0.06642	0.2202	0.1694	AHI1/CITED2/SETDB2/MNS1	4
BP	GO:0071285	cellular response to lithium ion	4/2306	13/18670	0.06642	0.2202	0.1694	ID2/ADCY7/XRCC4/CEBPA	4
BP	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading	4/2306	13/18670	0.06642	0.2202	0.1694	CORO1C/GBP1/TACSTD2/ACTN4	4
BP	GO:1902306	negative regulation of sodium ion transmembrane transport	4/2306	13/18670	0.06642	0.2202	0.1694	CAMK2D/HECW2/OSR1/NEDD4	4
BP	GO:0097164	ammonium ion metabolic process	33/2306	205/18670	0.0665	0.2202	0.1694	AKR1B1/LPIN1/SAT1/PLA2G4A/SLC22A4/RAB38/FABP3/PNKD/PLA2G4C/GCH1/DBI/SMOX/CROT/SRD5A1/HNMT/CPT1A/TGFB2/PRG3/MOXD1/CBR4/PLA2G12A/VPS35/ALDH7A1/ABAT/ABHD3/PRKCD/SGMS2/CHKB/DHPS/SAMD8/ACADM/CAPN2/STARD7	33
BP	GO:0010811	positive regulation of cell-substrate adhesion	21/2306	121/18670	0.06662	0.2202	0.1694	NINJ1/CDK6/CSF1/VEGFA/ROCK1/NEDD9/MYADM/LIMS2/CCDC80/RSU1/HAS2/ARPC2/HSD17B12/COL16A1/SDC4/ABL1/EPHA1/CDC42/FERMT1/ITGA6/CRKL	21
BP	GO:0034248	regulation of cellular amide metabolic process	71/2306	483/18670	0.06685	0.2202	0.1694	ZC3H12A/CCL5/IL6/ACO1/HSPB1/DIO2/IFNGR1/EIF4A2/DAPK1/CAPRIN1/SLC7A11/PPP1R15A/ROCK1/MOV10/NGDN/RXRA/FTO/DPH5/ENC1/THBS1/ZFP36/MKNK2/EIF2AK4/ZFP36L2/PRG3/EIF4G3/RGS2/DNAJC3/ITGA2/MPV17L2/RPL22/EIF1/BCL3/SECISBP2L/MIR19B2/PABPC1/DHX29/BTG2/SAMD4B/SESN2/NSUN3/EIF3E/TNF/PUS7/MIR1-2/MIR125B1/CNOT8/EIF2B5/EIF2B4/MIR298/SYNCRIP/PRKCD/FASTKD3/PDK3/ROCK2/FXR2/PER1/NSMAF/TMED10/YTHDF1/ZNF706/ZNF540/ATP13A2/IGF1/MRPL13/MIR218-1/STAT3/SAMD8/PICALM/EIF1B/ZNF598	71
BP	GO:0001783	B cell apoptotic process	6/2306	24/18670	0.06691	0.2202	0.1694	TRAF3IP2/SLC39A10/ADA/FNIP1/BCL10/CRKL	6
BP	GO:0006862	nucleotide transport	6/2306	24/18670	0.06691	0.2202	0.1694	SLC25A24/ABCD1/SLC25A33/P2RX7/SLC25A36/ABCC11	6
BP	GO:0032528	microvillus organization	6/2306	24/18670	0.06691	0.2202	0.1694	PLD1/FSCN1/ATP8B1/RDX/PODXL/PTPN11	6
BP	GO:0036010	protein localization to endosome	6/2306	24/18670	0.06691	0.2202	0.1694	ANKRD13A/MICALL1/RDX/VPS35/ARF6/ROCK2	6
BP	GO:0042832	defense response to protozoan	6/2306	24/18670	0.06691	0.2202	0.1694	GBP2/IL12A/IL4R/CD40/GBP4/BCL3	6
BP	GO:0043302	positive regulation of leukocyte degranulation	6/2306	24/18670	0.06691	0.2202	0.1694	IL4R/HLA-F/SNX4/STXBP1/VAMP7/NPPA	6
BP	GO:0046697	decidualization	6/2306	24/18670	0.06691	0.2202	0.1694	PTGS2/LIF/CYP27B1/GJB2/VDR/JUNB	6
BP	GO:0060396	growth hormone receptor signaling pathway	6/2306	24/18670	0.06691	0.2202	0.1694	PXN/GHR/STAT6/GDF15/SOCS2/STAT3	6
BP	GO:0071677	positive regulation of mononuclear cell migration	6/2306	24/18670	0.06691	0.2202	0.1694	CCL5/CXCL10/PDGFD/CCL1/TNF/SERPINE1	6
BP	GO:0086064	cell communication by electrical coupling involved in cardiac conduction	6/2306	24/18670	0.06691	0.2202	0.1694	GJD3/CALM1/PDE4D/CAMK2D/CALM2/SRI	6
BP	GO:0090103	cochlea morphogenesis	6/2306	24/18670	0.06691	0.2202	0.1694	SIX1/FZD2/WNT5A/PTK7/DVL1/DVL2	6
BP	GO:0099563	modification of synaptic structure	6/2306	24/18670	0.06691	0.2202	0.1694	PFN2/STAU1/ABL1/CDC42/MYH10/GRIPAP1	6
BP	GO:1903421	regulation of synaptic vesicle recycling	6/2306	24/18670	0.06691	0.2202	0.1694	PPP3CC/ROCK1/VAMP4/CDK5/TOR1A/GRIPAP1	6
BP	GO:2000178	negative regulation of neural precursor cell proliferation	6/2306	24/18670	0.06691	0.2202	0.1694	ID2/LIMS2/WNT5A/BTG2/MIR137/APPL2	6
BP	GO:0002639	positive regulation of immunoglobulin production	9/2306	42/18670	0.06737	0.2213	0.1703	IL6/IL33/HLA-E/IL4R/CD40/EXOSC6/CLCF1/STAT6/SASH3	9
BP	GO:0010907	positive regulation of glucose metabolic process	9/2306	42/18670	0.06737	0.2213	0.1703	PPARGC1A/FOXO1/IRS1/DYRK2/PMAIP1/KAT2B/SIRT1/RGN/IGF1	9
BP	GO:0002287	alpha-beta T cell activation involved in immune response	12/2306	61/18670	0.06748	0.2213	0.1703	NFKBIZ/ZC3H12A/IL6/RELB/RIPK2/IL18R1/MYB/IL4R/STAT6/BCL3/GATA3/STAT3	12
BP	GO:0002293	alpha-beta T cell differentiation involved in immune response	12/2306	61/18670	0.06748	0.2213	0.1703	NFKBIZ/ZC3H12A/IL6/RELB/RIPK2/IL18R1/MYB/IL4R/STAT6/BCL3/GATA3/STAT3	12
BP	GO:0006879	cellular iron ion homeostasis	12/2306	61/18670	0.06748	0.2213	0.1703	SLC11A2/ACO1/FTH1/NDFIP1/CAND1/ABCG2/HMOX2/CYBRD1/FTHL17/FBXL5/ATP13A2/SRI	12
BP	GO:0071384	cellular response to corticosteroid stimulus	12/2306	61/18670	0.06748	0.2213	0.1703	ICAM1/FOXO1/CFLAR/ZFP36/EDN1/SRD5A1/ZFP36L2/SMYD3/ERRFI1/GJB2/ABCC2/ASS1	12
BP	GO:1901216	positive regulation of neuron death	17/2306	94/18670	0.06752	0.2214	0.1703	ITGA1/DAXX/MYB/FYN/BACE1/CCL3/SSH1/UBE2M/TGFB2/CDK5/WNT5A/ADORA1/TNF/MIR125B1/ABL1/CAPN2/PICALM	17
BP	GO:0010675	regulation of cellular carbohydrate metabolic process	24/2306	142/18670	0.06792	0.2226	0.1712	PPARGC1A/C1QTNF1/FOXO1/PPP1R3F/ACACB/COX11/IRS1/NFE2L1/DYRK2/PHLDA2/ENPP1/PMAIP1/KAT2B/SIRT1/RGN/SESN2/DUSP12/PDK3/SLC35B4/SIK1/IGF1/GNMT/STAT3/SIRT6	24
BP	GO:0006022	aminoglycan metabolic process	28/2306	170/18670	0.068	0.2227	0.1714	IL1B/ST3GAL1/NFKB1/FGF2/PDGFRB/GPC4/B4GALT3/CD44/VCAN/CHST7/HSPG2/IL15/PIM1/GLB1/CLTC/SDC2/CSGALNACT1/HAS2/CSGALNACT2/GALNT5/ITIH1/HAS1/HAS3/EXT1/ST3GAL3/SDC4/HS2ST1/ST3GAL4	28
BP	GO:0051170	import into nucleus	27/2306	163/18670	0.06812	0.223	0.1715	NFKBIA/ZC3H12A/PTGS2/RAB23/BMP4/NUP133/LMNA/DDX20/PIK3R2/UBR5/ARNTL/KPNA3/RPAIN/APPL2/PRKCD/PPP3CA/NXT1/PKIG/HTATIP2/CDKN1A/KPNA2/RANBP17/NUP35/FERMT1/CBLB/STAT3/CHP2	27
BP	GO:0045216	cell-cell junction organization	26/2306	156/18670	0.06815	0.223	0.1715	CLDN1/FSCN1/PRKCA/GJD3/ROCK1/RAB13/CNTNAP1/VCL/LIMS2/EPB41L3/F2R/TGFB2/SNAI2/GJB2/UGT8/TNF/ACTN4/PKP4/ROCK2/PKN2/TJP1/CDH4/TLN1/PDCD6IP/NPHP1/CBFB	26
BP	GO:0009410	response to xenobiotic stimulus	45/2306	292/18670	0.06845	0.2231	0.1716	ICAM1/CBR3/CLDN1/ADORA2A/PPARGC1A/ARNT2/FOXO1/AHR/CFLAR/CMBL/GSTO1/GSTA4/CYP2U1/FADD/OXTR/ADA/EDN1/BPHL/SRD5A1/GHR/HNMT/CRYZ/PPP1R9B/RGS2/SMYD3/CYP1A2/ERRFI1/GJB2/CDK5/RGS4/ABCC2/ATG7/ABAT/CYB5B/ASS1/CNR2/PHGDH/CPS1/PPP3CA/PPARG/PTGS1/MGST2/CYP2C19/HOMER2/CYP2S1	45
BP	GO:0002755	MyD88-dependent toll-like receptor signaling pathway	8/2306	36/18670	0.06859	0.2231	0.1716	IRAK2/TNIP1/IRF1/IRAK4/IRF7/IRAK3/MAP3K1/UBB	8
BP	GO:0010573	vascular endothelial growth factor production	8/2306	36/18670	0.06859	0.2231	0.1716	PTGS2/IL6/IL1B/IL1A/C3/IL6ST/SULF2/SULF1	8
BP	GO:0071634	regulation of transforming growth factor beta production	8/2306	36/18670	0.06859	0.2231	0.1716	PTGS2/MYB/LRRC32/THBS1/TGFB2/ITGB8/GATA6/SERPINF2	8
BP	GO:0000002	mitochondrial genome maintenance	7/2306	30/18670	0.06869	0.2231	0.1716	PPARGC1A/TYMP/ATG7/SESN2/SLC25A33/POLG2/SLC25A36	7
BP	GO:0002828	regulation of type 2 immune response	7/2306	30/18670	0.06869	0.2231	0.1716	IL6/IL33/RSAD2/IDO1/IL4R/STAT6/GATA3	7
BP	GO:0010743	regulation of macrophage derived foam cell differentiation	7/2306	30/18670	0.06869	0.2231	0.1716	NFKBIA/CSF2/NFKB1/ABCA1/CSF1/ABCA5/PPARG	7
BP	GO:0032607	interferon-alpha production	7/2306	30/18670	0.06869	0.2231	0.1716	RIPK2/IFIH1/STAT1/IRF7/DDX58/HAVCR2/TLR3	7
BP	GO:0035066	positive regulation of histone acetylation	7/2306	30/18670	0.06869	0.2231	0.1716	IL1B/LIF/PPARGC1A/AUTS2/SNAI2/RPS6KA4/GATA3	7
BP	GO:0036258	multivesicular body assembly	7/2306	30/18670	0.06869	0.2231	0.1716	CHMP1B/CHMP4B/VPS37D/VPS36/VPS37C/CHMP5/PDCD6IP	7
BP	GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	7/2306	30/18670	0.06869	0.2231	0.1716	NFKBIZ/CD83/RIPK2/MYB/IL4R/SOCS1/SASH3	7
BP	GO:0046596	regulation of viral entry into host cell	7/2306	30/18670	0.06869	0.2231	0.1716	IFITM1/TRIM25/TRIM21/GSN/PTX3/TRIM38/SNX3	7
BP	GO:0048873	homeostasis of number of cells within a tissue	7/2306	30/18670	0.06869	0.2231	0.1716	CSF1/LIPA/F2R/FH/PTPN11/P2RX7/SASH3	7
BP	GO:0061157	mRNA destabilization	7/2306	30/18670	0.06869	0.2231	0.1716	ZC3H12A/ROCK1/MOV10/FTO/ZFP36/ZFP36L2/ROCK2	7
BP	GO:0006839	mitochondrial transport	40/2306	256/18670	0.06922	0.2247	0.1729	BID/SLC25A24/PPP3CC/SLC25A28/PDCD5/HK2/ACACB/DNAJC19/PPIF/SLC25A37/PMAIP1/MIPEP/ARIH2/CPT1A/TOMM34/ACACA/DNAJC15/ABCB10/RHOU/VPS35/BCL2L1/TP63/ACAA2/PARL/YWHAH/SLC25A20/BAP1/GRPEL1/GRPEL2/PRKAB2/TMEM14A/CHCHD4/SLC25A33/TFDP1/STAT3/SLC25A36/EYA2/MID1IP1/SLC25A16/TIMM17B	40
BP	GO:0071560	cellular response to transforming growth factor beta stimulus	39/2306	249/18670	0.06996	0.2269	0.1746	CLDN1/PPARGC1A/CITED2/DAB2/PDCD5/CFLAR/COL1A1/FYN/LRRC32/ITGB5/BMPR2/THBS1/EDN1/PXN/ZFP36L2/SDCBP/HIPK2/PDGFD/SOX5/TGFB2/GDF5/MEF2C/SIRT1/WNT5A/GDF15/CDKN1C/FBN1/APPL2/FERMT2/LTBP2/ZYX/COL1A2/UBB/ENG/FERMT1/USP9X/ZNF451/CRKL/SMAD9	39
BP	GO:0015696	ammonium transport	19/2306	108/18670	0.06999	0.2269	0.1746	CSF2/ADORA2A/SLC22A1/SLC38A2/SLC22A4/SNX4/SLC12A2/ADA/EDN1/SYT4/ABAT/SLC25A20/RALBP1/SYT1/SLC22A3/TOR1A/VAMP7/RHD/NPPA	19
BP	GO:0001541	ovarian follicle development	11/2306	55/18670	0.0706	0.2285	0.1758	ICAM1/KIT/CEBPB/VEGFA/EREG/INHBB/BCL2L1/EIF2B5/EIF2B4/PTX3/ZNF830	11
BP	GO:0010823	negative regulation of mitochondrion organization	11/2306	55/18670	0.0706	0.2285	0.1758	PPARGC1A/PPIF/LMNA/FNIP2/FNIP1/ATG7/BCL2L1/ACAA2/IAPP/TMEM14A/IGF1	11
BP	GO:0070830	bicellular tight junction assembly	11/2306	55/18670	0.0706	0.2285	0.1758	CLDN1/ROCK1/RAB13/SNAI2/TNF/ACTN4/ROCK2/TJP1/PDCD6IP/NPHP1/CBFB	11
BP	GO:0046777	protein autophosphorylation	37/2306	235/18670	0.07138	0.231	0.1777	ERN1/KIT/DAPK1/VEGFA/EEF2K/PAK1/PDGFRB/IRAK3/FYN/CALM1/PIM2/CAMK2D/PIM1/MKNK2/STK4/EIF2AK4/ENPP1/PDGFD/CSNK1G2/ERRFI1/CDK5/CAMKK2/PPP2R5E/CALM2/FRK/PDGFC/NEK6/ABL1/PPP2R5C/CLK4/EPHA1/ENG/MEX3B/ROS1/SIK1/ATP13A2/TAOK1	37
BP	GO:0009791	post-embryonic development	16/2306	88/18670	0.07162	0.2315	0.1781	ACO1/ARID5B/VEGFA/BMP4/KLF4/MYO1E/ERCC2/CYP1A2/IGF2R/RAB3A/FBN1/ALDH5A1/GATA3/PRDM1/ABL1/MORC3	16
BP	GO:0043312	neutrophil degranulation	71/2306	485/18670	0.07163	0.2315	0.1781	CXCL1/OLR1/TNFAIP6/PLD1/NFKB1/ANPEP/PSMB7/PYGL/C3/TNFRSF1B/ROCK1/CNN2/CTSS/TOM1/VCL/FRMPD3/PLAU/CD44/CD58/FTH1/IDH1/AMPD3/CYBA/GLA/COMMD3/GSDMD/GLB1/SDCBP/SIRPA/METTL7A/PRG3/CAND1/DNAJC3/PPIA/IGF2R/MMP9/S100A11/CEP290/IMPDH2/CPNE3/CRISPLD2/ATG7/RAB3A/PAFAH1B2/RAB18/GSN/HMOX2/CEACAM3/DYNLL1/ACTR10/SERPINB1/GYG1/RAB9B/FRK/PTX3/DIAPH1/PRKCD/AGA/HBB/VAMP7/ACTR2/TBC1D10C/SERPINA3/GCA/CSTB/ALDOC/SERPINA1/RAB31/UBR4/HLA-H/ADAM8	71
BP	GO:0070588	calcium ion transmembrane transport	48/2306	315/18670	0.07187	0.2322	0.1786	BDKRB1/CXCL10/FGF2/PLCE1/PANX1/GSTO1/RRAD/FYN/CALM1/PDE4D/CAMK2D/PKD2/CXCL11/CCL3/CYBA/UBASH3B/CACHD1/CXCL9/THADA/TRPC1/F2R/GJC2/ITPR2/GEM/STAC/TPCN1/RGN/CACNA1F/PARL/CACNA1B/CALM2/ATP2A2/MIR1-2/STIM1/FKBP1A/DIAPH1/GRIN3A/ABL1/PDE4B/VDAC1/ORAI1/GAS6/MCOLN1/NPPA/SRI/P2RX7/CASQ1/ADRA2A	48
BP	GO:0045787	positive regulation of cell cycle	58/2306	389/18670	0.07315	0.2362	0.1817	IL1B/ID2/IL1A/GDPD5/CITED2/PRKCA/EREG/PLK2/PDGFRB/PKD2/CCND1/CDC25A/SMARCD3/MSX2/EDN1/PRMT1/RDX/TGFA/GPSM2/CDC14B/TGFB2/GATA6/DUSP3/LRP5/CARM1/NSMCE2/WNT5A/NKX3-1/TRIM21/BTG2/RAD23A/ARID3A/CCNYL1/CNOT8/ASNS/PKP4/FEN1/ABL1/ROCK2/SETMAR/MIR214/POLDIP2/CDKN1A/PTPN11/FGF10/MNAT1/PKN2/TFDP1/CDC42/SH2B1/CCPG1/MEPCE/IGF1/MYBBP1A/FOXO4/NPM2/TBX3/DYNLT3	58
BP	GO:0050810	regulation of steroid biosynthetic process	17/2306	95/18670	0.07319	0.2362	0.1817	BMP2/IL1B/NFKB1/PPARGC1A/INSIG2/ACACB/SCD/DDX20/CYP27B1/TM7SF2/ACACA/SNAI2/VDR/SIRT1/TNF/GPAM/IDI1	17
BP	GO:0002534	cytokine production involved in inflammatory response	10/2306	49/18670	0.07358	0.2373	0.1826	ZC3H12A/IDO1/GBP5/SIRPA/ADCY7/ABCD1/APPL2/BAP1/PER1/TICAM1	10
BP	GO:0032482	Rab protein signal transduction	14/2306	75/18670	0.07372	0.2375	0.1828	RAB23/RAB9A/RAB13/RAB38/RAB33A/RAB2B/RAB40B/RAB4A/RAB32/RAB3A/RAB18/RAB9B/GDI1/RAB31	14
BP	GO:1903201	regulation of oxidative stress-induced cell death	14/2306	75/18670	0.07372	0.2375	0.1828	SOD2/GPR37L1/HSPB1/MMP3/NCOA7/SLC7A11/FZD1/LANCL1/FYN/NME5/SIRT1/ATG7/TXN/OXR1	14
BP	GO:0002064	epithelial cell development	33/2306	207/18670	0.07399	0.2383	0.1833	ICAM1/IL1B/S1PR3/CLDN1/CDK6/VEGFA/ROCK1/BMP4/RAB13/PDE4D/MYADM/SHROOM3/MYO1E/RDX/PODXL/ARNTL/YIPF6/WNT5B/FLNB/WNT5A/KRT2/TP63/TNF/C1GALT1/PRDM1/ROCK2/CDKN1A/ENG/ROS1/TJP1/PALLD/RILPL1/ARID4A	33
BP	GO:0035335	peptidyl-tyrosine dephosphorylation	18/2306	102/18670	0.07443	0.2396	0.1843	PTPRE/DUSP6/DUSP14/CDC25A/SSH1/UBASH3B/PTPN13/DUSP23/CDC14B/DUSP3/PTPRM/DUSP12/DUSP16/DUSP18/DUSP10/PTPN11/DUSP5/EYA2	18
BP	GO:0045453	bone resorption	12/2306	62/18670	0.07469	0.2398	0.1845	TNFAIP3/IL6/PRKCA/UBASH3B/TMEM64/BGLAP/IAPP/TNFRSF11B/P2RX7/ADAM8/ZNF675/SNX10	12
BP	GO:0046635	positive regulation of alpha-beta T cell activation	12/2306	62/18670	0.07469	0.2398	0.1845	NFKBIZ/CD83/RIPK2/HLA-E/IL12A/MYB/IL4R/SOCS1/ADA/EBI3/SASH3/CBFB	12
BP	GO:0046824	positive regulation of nucleocytoplasmic transport	12/2306	62/18670	0.07469	0.2398	0.1845	ZC3H12A/PTGS2/IL1B/PIK3R2/UBR5/TCF7L2/CPSF6/PRKCD/CTDSPL2/GAS6/NEDD4/CHP2	12
BP	GO:0060393	regulation of pathway-restricted SMAD protein phosphorylation	12/2306	62/18670	0.07469	0.2398	0.1845	BMP2/DAB2/BMP4/BMPR2/BMPER/INHBB/SDCBP/TGFB2/GDF5/GDF15/ENG/GDF6	12
BP	GO:1901862	negative regulation of muscle tissue development	12/2306	62/18670	0.07469	0.2398	0.1845	BMP2/MEIS1/JARID2/BMP4/PAK1/RGS2/SIX4/AKIRIN1/RGS4/MIR1-2/MIR199A2/FZD7	12
BP	GO:0050851	antigen receptor-mediated signaling pathway	48/2306	316/18670	0.07497	0.2406	0.1851	NFKBIZ/ZC3H12A/PSME2/RIPK2/KCNN4/NFKB1/PSMA6/PSMB10/PSMB8/PIK3CD/PSMB7/LPXN/PSME1/BTN3A1/PAK1/PSMB9/FYN/PDE4D/PSMA3/GBP1/SLC39A10/BTN2A1/PIK3R2/CYLD/ADA/BTN3A3/DUSP3/PSMA1/MEF2C/PSMB2/PSMB3/CACNA1F/EIF2B5/EIF2B4/CD79A/PVRIG/GATA3/PSMA8/HLA-DQB1/ABL1/RBCK1/BCL10/PDE4B/PSME4/PSMB5/CRKL/PSMF1/CBFB	48
BP	GO:0006493	protein O-linked glycosylation	19/2306	109/18670	0.07539	0.2408	0.1852	ST3GAL1/GALNT10/IL15/TET1/GXYLT1/POMGNT1/PGM3/GALNT5/GCNT1/TET3/C1GALT1/ST3GAL3/GALNT4/MUC15/MUC17/GALNT11/GALNT1/SLC35C1/ST3GAL4	19
BP	GO:0006337	nucleosome disassembly	5/2306	19/18670	0.07573	0.2408	0.1852	SET/SMARCD3/ARID1A/PBRM1/SMARCE1	5
BP	GO:0006555	methionine metabolic process	5/2306	19/18670	0.07573	0.2408	0.1852	MTHFD2L/MTR/BHMT2/MTAP/GNMT	5
BP	GO:0007096	regulation of exit from mitosis	5/2306	19/18670	0.07573	0.2408	0.1852	CDC14B/PPP1R9B/CDKN1C/CDC23/NPM2	5
BP	GO:0010523	negative regulation of calcium ion transport into cytosol	5/2306	19/18670	0.07573	0.2408	0.1852	GSTO1/CALM1/PKD2/CALM2/SRI	5
BP	GO:0030150	protein import into mitochondrial matrix	5/2306	19/18670	0.07573	0.2408	0.1852	DNAJC19/DNAJC15/GRPEL1/GRPEL2/TIMM17B	5
BP	GO:0030859	polarized epithelial cell differentiation	5/2306	19/18670	0.07573	0.2408	0.1852	AHI1/WNT5A/TP63/PTK7/CDC42	5
BP	GO:0045063	T-helper 1 cell differentiation	5/2306	19/18670	0.07573	0.2408	0.1852	RELB/RIPK2/IL18R1/IL4R/STAT6	5
BP	GO:0045414	regulation of interleukin-8 biosynthetic process	5/2306	19/18670	0.07573	0.2408	0.1852	KLF4/PRG3/BCL3/TNF/BCL10	5
BP	GO:0046597	negative regulation of viral entry into host cell	5/2306	19/18670	0.07573	0.2408	0.1852	IFITM1/TRIM25/GSN/PTX3/SNX3	5
BP	GO:0060149	negative regulation of posttranscriptional gene silencing	5/2306	19/18670	0.07573	0.2408	0.1852	ZC3H12A/ADAR/PPP3CA/NCOR2/PPARG	5
BP	GO:0060252	positive regulation of glial cell proliferation	5/2306	19/18670	0.07573	0.2408	0.1852	IL6/IL1B/MYB/TNF/MIR125B1	5
BP	GO:0060967	negative regulation of gene silencing by RNA	5/2306	19/18670	0.07573	0.2408	0.1852	ZC3H12A/ADAR/PPP3CA/NCOR2/PPARG	5
BP	GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response	5/2306	19/18670	0.07573	0.2408	0.1852	DDX58/WNT5A/HLA-G/BCL10/TICAM1	5
BP	GO:0072576	liver morphogenesis	5/2306	19/18670	0.07573	0.2408	0.1852	TNFAIP3/CEBPB/CFLAR/LIMS2/SULF2	5
BP	GO:1903798	regulation of production of miRNAs involved in gene silencing by miRNA	5/2306	19/18670	0.07573	0.2408	0.1852	ZC3H12A/BMP4/DDX5/PPP3CA/NCOR2	5
BP	GO:1905288	vascular associated smooth muscle cell apoptotic process	5/2306	19/18670	0.07573	0.2408	0.1852	SOD2/STK4/MIR1-2/PPARG/IGF1	5
BP	GO:1905459	regulation of vascular associated smooth muscle cell apoptotic process	5/2306	19/18670	0.07573	0.2408	0.1852	SOD2/STK4/MIR1-2/PPARG/IGF1	5
BP	GO:0030098	lymphocyte differentiation	53/2306	353/18670	0.07577	0.2408	0.1852	NFKBIZ/ZC3H12A/IL6/VCAM1/RELB/CD83/RIPK2/ID2/SH3RF1/CDK6/IRF1/TNFSF9/KIT/PIK3CD/IL7R/MAFB/RSAD2/PRR7/BMP4/IL12A/IL18R1/MYB/IL4R/SOCS1/POU2F2/DNAJB9/FADD/ITGA4/IL15/CYLD/ADA/ZFP36L2/FNIP1/RPL22/CLCF1/STAT6/BCL3/AXL/FZD8/IRF2BP2/SLAMF8/CD79A/GATA3/HLA-G/PRDM1/ABL1/DUSP10/GAS6/STAT3/SASH3/FZD7/ADAM8/CBFB	53
BP	GO:0006855	drug transmembrane transport	15/2306	82/18670	0.07597	0.2408	0.1852	SLC7A2/ATP8B1/SLC22A2/SLC7A11/SLC22A1/ARL6IP5/SLC19A3/RGS2/ABCC1/RGS4/ABCC2/CLN8/RALBP1/SLC22A3/SLC19A1	15
BP	GO:0032637	interleukin-8 production	15/2306	82/18670	0.07597	0.2408	0.1852	IL1B/CD58/DDX58/KLF4/FADD/F2R/PRG3/BCL3/WNT5A/ANXA4/TNF/TLR3/SERPINE1/BCL10/MAPKBP1	15
BP	GO:0032642	regulation of chemokine production	15/2306	82/18670	0.07597	0.2408	0.1852	CXCL6/IL6/IL1B/RIPK2/IL33/IL4R/KLF4/MBP/SIRPA/SNAI2/WNT5A/HAVCR2/TNF/TLR3/TICAM1	15
BP	GO:0055117	regulation of cardiac muscle contraction	15/2306	82/18670	0.07597	0.2408	0.1852	ZC3H12A/GSTO1/CALM1/PDE4D/CAMK2D/RGS2/HCN4/ADORA1/CALM2/ATP2A2/MIR1-2/PDE4B/NPPA/PDE5A/SRI	15
BP	GO:1901293	nucleoside phosphate biosynthetic process	58/2306	390/18670	0.07597	0.2408	0.1852	NAMPT/PTGS2/PID1/PRPS1/PPARGC1A/SLC2A6/KYNU/MTHFD2L/IDO1/HK2/PRPS1L1/ACACB/ELOVL5/ENO2/ADPGK/CMPK2/NUP133/AK1/SCD/ELOVL7/AMPD3/PGM2L1/ADA/ACAT1/NNMT/PPT1/ADCY7/ACACA/NME5/ACSL5/CBR4/ADCY9/ADCY3/ELOVL2/PARP9/IMPDH2/PPCS/HSD17B12/CDADC1/PDHB/PAPSS1/GUK1/GPAM/ME1/PGAM4/NPR2/PDK3/TK2/NPPA/NUP35/DCK/IGF1/STAT3/ALDOC/P2RX7/SIRT6/ELOVL3/LCLAT1	58
BP	GO:0000096	sulfur amino acid metabolic process	9/2306	43/18670	0.07629	0.2408	0.1853	MTHFD2L/SLC7A11/PCYOX1/MTR/BHMT2/ADO/MTAP/CPS1/GNMT	9
BP	GO:0009163	nucleoside biosynthetic process	9/2306	43/18670	0.07629	0.2408	0.1853	TYMP/ADA/NME5/IMPDH2/GUK1/MTAP/PRTFDC1/TK2/DCK	9
BP	GO:0032881	regulation of polysaccharide metabolic process	9/2306	43/18670	0.07629	0.2408	0.1853	NFKB1/PPP1R3F/IRS1/DYRK2/PHLDA2/ENPP1/CLTC/HAS2/IGF1	9
BP	GO:0045773	positive regulation of axon extension	9/2306	43/18670	0.07629	0.2408	0.1853	NTN1/ZFYVE27/DBN1/VEGFA/PAK1/BMPR2/RUFY3/GDI1/CDH4	9
BP	GO:0055026	negative regulation of cardiac muscle tissue development	9/2306	43/18670	0.07629	0.2408	0.1853	BMP2/MEIS1/JARID2/PAK1/RGS2/RGS4/MIR1-2/MIR199A2/FZD7	9
BP	GO:1901658	glycosyl compound catabolic process	9/2306	43/18670	0.07629	0.2408	0.1853	TYMP/APOBEC3G/NUDT18/ADA/NAGA/GLA/APOBEC3H/CDADC1/APOBEC3F	9
BP	GO:1901985	positive regulation of protein acetylation	9/2306	43/18670	0.07629	0.2408	0.1853	IL1B/LIF/PPARGC1A/AUTS2/ARNTL/SNAI2/RPS6KA4/GATA3/TAOK1	9
BP	GO:1904646	cellular response to amyloid-beta	9/2306	43/18670	0.07629	0.2408	0.1853	ICAM1/NAMPT/VCAM1/BCL2L2/FYN/BACE1/ITGA4/CDK5/IGF1	9
BP	GO:1901605	alpha-amino acid metabolic process	35/2306	222/18670	0.07651	0.2414	0.1857	GFPT2/DDAH1/KYNU/GLS/MTHFD2L/IDO1/SLC7A11/PSPH/HIBCH/IL4I1/FAH/P4HA2/ACAT1/GLUD1/EGLN1/HNMT/SEPHS1/PSAT1/AADAT/PLOD2/GAMT/HIBADH/AMT/ALDH7A1/MTR/ASS1/BHMT2/ASNS/DDAH2/ALDH5A1/PHGDH/MTAP/CPS1/GNMT/BCAT2	35
BP	GO:0002062	chondrocyte differentiation	21/2306	123/18670	0.07663	0.2415	0.1858	BMP2/BMP4/BMPR2/HOXA11/MSX2/SCARA3/SULF2/PTHLH/CYTL1/SOX5/SNAI2/WNT5B/GDF5/MEF2C/SULF1/COL6A3/OSR2/SERPINH1/GDF6/OSR1/NFIB	21
BP	GO:0009116	nucleoside metabolic process	21/2306	123/18670	0.07663	0.2415	0.1858	RAB23/PRPS1/TYMP/PRPS1L1/APOBEC3G/AMPD3/NUDT18/ADA/APOBEC3H/NT5C2/NME5/IMPDH2/GAMT/CDADC1/GUK1/MTAP/PRTFDC1/APOBEC3F/TK2/DCK/GNMT	21
BP	GO:0060021	roof of mouth development	16/2306	89/18670	0.07776	0.2449	0.1884	MSC/ARID5B/INSIG2/FZD1/LRRC32/DHRS3/FZD2/TGFB2/SNAI2/BNC2/MEOX2/MEF2C/WNT5A/OSR2/OSR1/TBX3	16
BP	GO:0071300	cellular response to retinoic acid	13/2306	69/18670	0.07797	0.2455	0.1888	ABCA1/MYB/COL1A1/KLF4/WNT5B/YAP1/WNT5A/TNC/PTK7/FZD4/PPARG/OSR1/FZD7	13
BP	GO:0007431	salivary gland development	8/2306	37/18670	0.07846	0.2457	0.1891	TGFB2/SNAI2/POLB/NKX3-1/TNF/PLXND1/FGF10/NFIB	8
BP	GO:0014912	negative regulation of smooth muscle cell migration	8/2306	37/18670	0.07846	0.2457	0.1891	TRIB1/PPARGC1A/SLIT2/MEF2C/MIR137/SERPINE1/MIR214/MIR218-1	8
BP	GO:0032885	regulation of polysaccharide biosynthetic process	8/2306	37/18670	0.07846	0.2457	0.1891	NFKB1/PPP1R3F/IRS1/DYRK2/ENPP1/CLTC/HAS2/IGF1	8
BP	GO:0060323	head morphogenesis	8/2306	37/18670	0.07846	0.2457	0.1891	ARID5B/COL1A1/RAB3GAP1/CRISPLD2/CRISPLD1/PTPN11/ANKRD11/SSBP3	8
BP	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	8/2306	37/18670	0.07846	0.2457	0.1891	NEDD9/MYADM/LIMS2/HAS2/ARPC2/ABL1/CDC42/CRKL	8
BP	GO:0000768	syncytium formation by plasma membrane fusion	11/2306	56/18670	0.0785	0.2457	0.1891	CXCL10/MYOF/CFLAR/IL4R/CXCL9/FLOT1/EHD1/PLEKHO1/GDF15/MYH9/CAPN2	11
BP	GO:0006749	glutathione metabolic process	11/2306	56/18670	0.0785	0.2457	0.1891	PTGES/SLC7A11/GSTA4/NFE2L1/IDH1/CHAC2/HAGH/ALDH5A1/GLRX2/CNDP2/MGST2	11
BP	GO:0009435	NAD biosynthetic process	11/2306	56/18670	0.0785	0.2457	0.1891	NAMPT/PTGS2/KYNU/IDO1/HK2/ENO2/ADPGK/PGM2L1/NNMT/PARP9/ALDOC	11
BP	GO:0032615	interleukin-12 production	11/2306	56/18670	0.0785	0.2457	0.1891	RIPK2/NFKB1/IRF1/IDO1/CMKLR1/CD40/IRAK3/THBS1/TLR3/PRKCD/HLA-G	11
BP	GO:0120192	tight junction assembly	11/2306	56/18670	0.0785	0.2457	0.1891	CLDN1/ROCK1/RAB13/SNAI2/TNF/ACTN4/ROCK2/TJP1/PDCD6IP/NPHP1/CBFB	11
BP	GO:0140253	cell-cell fusion	11/2306	56/18670	0.0785	0.2457	0.1891	CXCL10/MYOF/CFLAR/IL4R/CXCL9/FLOT1/EHD1/PLEKHO1/GDF15/MYH9/CAPN2	11
BP	GO:0001562	response to protozoan	6/2306	25/18670	0.07922	0.2465	0.1896	GBP2/IL12A/IL4R/CD40/GBP4/BCL3	6
BP	GO:0002507	tolerance induction	6/2306	25/18670	0.07922	0.2465	0.1896	TNFAIP3/IDO1/HLA-E/IRAK3/HAVCR2/HLA-G	6
BP	GO:0045332	phospholipid translocation	6/2306	25/18670	0.07922	0.2465	0.1896	KCNN4/ABCA1/ATP8B1/ABCC1/ATP8A2/TMEM30B	6
BP	GO:0045956	positive regulation of calcium ion-dependent exocytosis	6/2306	25/18670	0.07922	0.2465	0.1896	CDK5/KCNB1/SYT4/ARF1/STXBP1/SYT1	6
BP	GO:0046755	viral budding	6/2306	25/18670	0.07922	0.2465	0.1896	CHMP1B/CHMP4B/VPS37D/VPS37C/CHMP5/PDCD6IP	6
BP	GO:0060444	branching involved in mammary gland duct morphogenesis	6/2306	25/18670	0.07922	0.2465	0.1896	CSF1/MSX2/LRP5/VDR/WNT5A/TBX3	6
BP	GO:0060571	morphogenesis of an epithelial fold	6/2306	25/18670	0.07922	0.2465	0.1896	BMP4/RDH10/WNT5A/SULF1/TP63/FGF10	6
BP	GO:0071378	cellular response to growth hormone stimulus	6/2306	25/18670	0.07922	0.2465	0.1896	PXN/GHR/STAT6/GDF15/SOCS2/STAT3	6
BP	GO:0090025	regulation of monocyte chemotaxis	6/2306	25/18670	0.07922	0.2465	0.1896	CCL5/CXCL10/SLIT2/CCL1/SLAMF8/SERPINE1	6
BP	GO:1900101	regulation of endoplasmic reticulum unfolded protein response	6/2306	25/18670	0.07922	0.2465	0.1896	ERN1/PPP1R15A/FICD/DNAJB9/TMEM33/BFAR	6
BP	GO:1904385	cellular response to angiotensin	6/2306	25/18670	0.07922	0.2465	0.1896	NFKB1/AGTRAP/ROCK1/CYBA/PRKCD/ROCK2	6
BP	GO:2000353	positive regulation of endothelial cell apoptotic process	6/2306	25/18670	0.07922	0.2465	0.1896	CCL2/CD248/CD40/ITGA4/THBS1/HLA-G	6
BP	GO:0002283	neutrophil activation involved in immune response	71/2306	488/18670	0.07924	0.2465	0.1896	CXCL1/OLR1/TNFAIP6/PLD1/NFKB1/ANPEP/PSMB7/PYGL/C3/TNFRSF1B/ROCK1/CNN2/CTSS/TOM1/VCL/FRMPD3/PLAU/CD44/CD58/FTH1/IDH1/AMPD3/CYBA/GLA/COMMD3/GSDMD/GLB1/SDCBP/SIRPA/METTL7A/PRG3/CAND1/DNAJC3/PPIA/IGF2R/MMP9/S100A11/CEP290/IMPDH2/CPNE3/CRISPLD2/ATG7/RAB3A/PAFAH1B2/RAB18/GSN/HMOX2/CEACAM3/DYNLL1/ACTR10/SERPINB1/GYG1/RAB9B/FRK/PTX3/DIAPH1/PRKCD/AGA/HBB/VAMP7/ACTR2/TBC1D10C/SERPINA3/GCA/CSTB/ALDOC/SERPINA1/RAB31/UBR4/HLA-H/ADAM8	71
BP	GO:0009394	2'-deoxyribonucleotide metabolic process	7/2306	31/18670	0.07968	0.2473	0.1903	CMPK2/NUDT18/ADA/NUDT1/CDADC1/GUK1/MBD4	7
BP	GO:0036257	multivesicular body organization	7/2306	31/18670	0.07968	0.2473	0.1903	CHMP1B/CHMP4B/VPS37D/VPS36/VPS37C/CHMP5/PDCD6IP	7
BP	GO:0044319	wound healing, spreading of cells	7/2306	31/18670	0.07968	0.2473	0.1903	PDPN/CD44/MSX2/HBEGF/PHLDB2/TOR1A/COL5A1	7
BP	GO:0090505	epiboly involved in wound healing	7/2306	31/18670	0.07968	0.2473	0.1903	PDPN/CD44/MSX2/HBEGF/PHLDB2/TOR1A/COL5A1	7
BP	GO:1902106	negative regulation of leukocyte differentiation	18/2306	103/18670	0.08025	0.249	0.1915	ZC3H12A/ID2/TRIB1/CDK6/IRF1/MAFB/BMP4/IL4R/SOCS1/CCL3/UBASH3B/FBN1/MIR125B1/TLR3/HLA-G/PIAS3/ZNF675/CBFB	18
BP	GO:0071466	cellular response to xenobiotic stimulus	29/2306	180/18670	0.08041	0.2493	0.1918	ICAM1/CBR3/PPARGC1A/ARNT2/FOXO1/AHR/CFLAR/CMBL/GSTO1/GSTA4/CYP2U1/BPHL/SRD5A1/GHR/CRYZ/PPP1R9B/SMYD3/CYP1A2/ERRFI1/GJB2/ABCC2/ATG7/CYB5B/ASS1/PHGDH/PTGS1/MGST2/CYP2C19/CYP2S1	29
BP	GO:0030500	regulation of bone mineralization	14/2306	76/18670	0.08057	0.2495	0.1919	BMP2/ISG15/BMP4/BMPR2/CCL3/CYP27B1/ENPP1/MEF2C/SRGN/BGLAP/BMP2K/OSR2/OSR1/P2RX7	14
BP	GO:0061045	negative regulation of wound healing	14/2306	76/18670	0.08057	0.2495	0.1919	SERPINB2/FGF2/C1QTNF1/PLAU/THBS1/UBASH3B/EDN1/PHLDB2/ABAT/PRKCD/SERPINE1/DUSP10/CDKN1A/SERPINF2	14
BP	GO:1901264	carbohydrate derivative transport	14/2306	76/18670	0.08057	0.2495	0.1919	SLC25A24/CYBA/ADA/SLC28A3/SLC35A1/ABCD1/ADORA1/GUK1/RALBP1/SLC35B4/SLC35B1/SLC37A1/SLC29A1/SLC35C1	14
BP	GO:0016525	negative regulation of angiogenesis	28/2306	173/18670	0.08091	0.2504	0.1926	CXCL10/THBS2/STAT1/ROCK1/PLK2/KLF2/KLF4/HSPG2/THBS1/E2F2/CARD10/TGFB2/STARD13/MEOX2/MIR19B2/SULF1/FOXJ2/MIR137/SPARC/MIR125B1/PTPRM/HLA-G/SERPINE1/ROCK2/MIR214/PDE3B/PPARG/FOXO4	28
BP	GO:1901222	regulation of NIK/NF-kappaB signaling	20/2306	117/18670	0.08162	0.2525	0.1942	NFKBIA/ZC3H12A/IL1B/BIRC2/IL18R1/TSPAN6/TRIP6/ZFP91/CYLD/EDN1/CARD10/BCL3/TRAF2/HAVCR2/TNF/TNFRSF10B/ACTN4/TLR3/RBCK1/PYDC2	20
BP	GO:0006665	sphingolipid metabolic process	26/2306	159/18670	0.08171	0.2526	0.1943	KIT/ST8SIA1/TEX2/ESYT1/ELOVL5/B4GALT3/UGCG/ELOVL7/A4GALT/NAGA/GLA/GLB1/PPT1/ITGB8/CSNK1G2/ELOVL2/UGT8/TNF/CLN8/ALDH5A1/PRKCD/SGMS2/NSMAF/P2RX7/SAMD8/ELOVL3	26
BP	GO:0008637	apoptotic mitochondrial changes	21/2306	124/18670	0.082	0.2532	0.1948	SOD2/BID/PPP3CC/PDCD5/HK2/PPIF/PIM2/LMNA/PMAIP1/MMP9/VPS35/BCL2L1/TP63/IFIT2/ACAA2/YWHAH/TMEM14A/TFDP1/FAM162A/IGF1/EYA2	21
BP	GO:0014013	regulation of gliogenesis	21/2306	124/18670	0.082	0.2532	0.1948	BMP2/IL6/GPR37L1/IL1B/LIF/ID2/CSF1/TNFRSF1B/IL6ST/MYB/CCL3/GJC2/CLCF1/DAAM2/ASCL2/HES5/TNF/MIR125B1/DUSP10/PPARG/CRKL	21
BP	GO:0032873	negative regulation of stress-activated MAPK cascade	10/2306	50/18670	0.08227	0.2535	0.195	FOXO1/DNAJA1/ITCH/CYLD/SIRPA/DUSP3/DUSP10/PER1/SH3RF2/ZNF675	10
BP	GO:0034656	nucleobase-containing small molecule catabolic process	10/2306	50/18670	0.08227	0.2535	0.195	ENTPD7/TYMP/APOBEC3G/NUDT18/ADA/APOBEC3H/NUDT1/CDADC1/MGAT1/APOBEC3F	10
BP	GO:0060425	lung morphogenesis	10/2306	50/18670	0.08227	0.2535	0.195	LIF/BMP4/RDH10/SPRY1/YAP1/TNC/TNF/RSPO2/FGF10/NFIB	10
BP	GO:0060976	coronary vasculature development	10/2306	50/18670	0.08227	0.2535	0.195	VEGFA/BMP4/PDGFRB/SGCD/GATA6/PTK7/MIR1-2/PLXND1/PRDM1/MYH10	10
BP	GO:0070303	negative regulation of stress-activated protein kinase signaling cascade	10/2306	50/18670	0.08227	0.2535	0.195	FOXO1/DNAJA1/ITCH/CYLD/SIRPA/DUSP3/DUSP10/PER1/SH3RF2/ZNF675	10
BP	GO:0046622	positive regulation of organ growth	12/2306	63/18670	0.08238	0.2535	0.1951	BASP1/FGF2/ACACB/PIM1/EDN1/GATA6/YAP1/MEF2C/MIR19B2/MIR199A2/IGF1/SASH3	12
BP	GO:2000401	regulation of lymphocyte migration	12/2306	63/18670	0.08238	0.2535	0.1951	CCL20/CCL5/CXCL10/CCL2/CCL7/TNFRSF14/CCL3/FADD/ITGA4/WNT5A/ADAM8/CRKL	12
BP	GO:0009101	glycoprotein biosynthetic process	52/2306	348/18670	0.08319	0.2558	0.1968	GFPT2/TNIP1/ST3GAL1/ST8SIA1/BACE2/MAN1A1/PHLDA1/B4GALT3/BMPR2/VCAN/GALNT10/CHST7/MAN1C1/A4GALT/IL15/TET1/TCF7L2/CYTL1/GXYLT1/HBEGF/SERP2/CSGALNACT1/SOAT1/CSGALNACT2/MOGS/POMGNT1/RAMP1/PGM3/GALNT5/MGAT1/MGAT2/GCNT1/TET3/CHST8/C1GALT1/EXT1/ST3GAL3/ALG3/HS2ST1/GALNT4/ACOT8/DAD1/DPY19L4/MUC15/MUC17/IGF1/ALG13/GALNT11/GALNT1/SLC35C1/TMEM165/ST3GAL4	52
BP	GO:0008654	phospholipid biosynthetic process	40/2306	260/18670	0.08337	0.2558	0.1968	PLD1/LPIN1/FGF2/PIK3CD/GPD1L/PLSCR1/PLA2G4A/RAB38/FABP3/PISD/PIGV/IDH1/PIK3R2/PTPN13/PIK3R3/RAB4A/PLEKHA3/CPNE3/PLA2G12A/ARF1/ARF3/ABHD5/ABHD3/GPAM/MPPE1/SGMS2/PIGK/PIGS/CHKB/IDI1/PIP4K2A/FAR1/PI4K2B/SH3YL1/SAMD8/SBF1/PLEKHA4/CAPN2/LCLAT1/STARD7	40
BP	GO:0002091	negative regulation of receptor internalization	4/2306	14/18670	0.08422	0.2558	0.1968	ANKRD13A/SDCBP/DLG4/MIR199A2	4
BP	GO:0003128	heart field specification	4/2306	14/18670	0.08422	0.2558	0.1968	BMP4/SMARCD3/ROBO1/MEF2C	4
BP	GO:0009214	cyclic nucleotide catabolic process	4/2306	14/18670	0.08422	0.2558	0.1968	PDE4D/PDE1A/PDE4B/PDE5A	4
BP	GO:0010935	regulation of macrophage cytokine production	4/2306	14/18670	0.08422	0.2558	0.1968	IRAK3/TGFB2/WNT5A/HLA-G	4
BP	GO:0015780	nucleotide-sugar transmembrane transport	4/2306	14/18670	0.08422	0.2558	0.1968	SLC35A1/SLC35B4/SLC35B1/SLC35C1	4
BP	GO:0031272	regulation of pseudopodium assembly	4/2306	14/18670	0.08422	0.2558	0.1968	KIT/CDC42EP1/CDC42EP3/CDC42	4
BP	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway	4/2306	14/18670	0.08422	0.2558	0.1968	NAMPT/PTGS2/NNMT/PARP9	4
BP	GO:0035810	positive regulation of urine volume	4/2306	14/18670	0.08422	0.2558	0.1968	ADORA2A/NPR3/EDN1/HAS2	4
BP	GO:0036295	cellular response to increased oxygen levels	4/2306	14/18670	0.08422	0.2558	0.1968	FOXO1/FAS/ATG7/PPARG	4
BP	GO:0042574	retinal metabolic process	4/2306	14/18670	0.08422	0.2558	0.1968	ALDH1A3/CYP27C1/RDH10/RDH13	4
BP	GO:0045953	negative regulation of natural killer cell mediated cytotoxicity	4/2306	14/18670	0.08422	0.2558	0.1968	HLA-E/HLA-F/HAVCR2/HLA-G	4
BP	GO:0046133	pyrimidine ribonucleoside catabolic process	4/2306	14/18670	0.08422	0.2558	0.1968	APOBEC3G/APOBEC3H/CDADC1/APOBEC3F	4
BP	GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development	4/2306	14/18670	0.08422	0.2558	0.1968	EDN1/MIR19B2/MIR199A2/IGF1	4
BP	GO:0070234	positive regulation of T cell apoptotic process	4/2306	14/18670	0.08422	0.2558	0.1968	CCL5/IDO1/WNT5A/ADAM8	4
BP	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade	4/2306	14/18670	0.08422	0.2558	0.1968	FHL2/DYRK2/RCAN1/HOMER2	4
BP	GO:0071361	cellular response to ethanol	4/2306	14/18670	0.08422	0.2558	0.1968	CCL7/ADCY7/TP53INP1/ITPR2	4
BP	GO:0106057	negative regulation of calcineurin-mediated signaling	4/2306	14/18670	0.08422	0.2558	0.1968	FHL2/DYRK2/RCAN1/HOMER2	4
BP	GO:1901722	regulation of cell proliferation involved in kidney development	4/2306	14/18670	0.08422	0.2558	0.1968	CFLAR/BMP4/PDGFD/GATA3	4
BP	GO:1904748	regulation of apoptotic process involved in development	4/2306	14/18670	0.08422	0.2558	0.1968	TNFRSF1B/TGFB2/VDR/MIR19B2	4
BP	GO:2000345	regulation of hepatocyte proliferation	4/2306	14/18670	0.08422	0.2558	0.1968	TNFAIP3/CFLAR/LIMS2/SULF2	4
BP	GO:2001279	regulation of unsaturated fatty acid biosynthetic process	4/2306	14/18670	0.08422	0.2558	0.1968	PTGS2/IL1B/ABCD1/SIRT1	4
BP	GO:0030901	midbrain development	16/2306	90/18670	0.08423	0.2558	0.1968	BASP1/FZD1/CALM1/GLUD1/MBP/SYPL2/CSNK1E/GNB4/WNT5A/ACTB/HES3/YWHAH/DYNLL1/CALM2/EN2/CDC42	16
BP	GO:0032651	regulation of interleukin-1 beta production	16/2306	90/18670	0.08423	0.2558	0.1968	ZC3H12A/TNFAIP3/S1PR3/RIPK2/HSPB1/PANX1/CCL3/GSDMD/SIRPA/F2R/ERRFI1/WNT5A/SERPINB1/PYDC2/IGF1/P2RX7	16
BP	GO:0046849	bone remodeling	16/2306	90/18670	0.08423	0.2558	0.1968	TNFAIP3/IL6/PRKCA/UBASH3B/MITF/TMEM64/GDF5/LRP5/BGLAP/IAPP/LGR4/TNFRSF11B/P2RX7/ADAM8/ZNF675/SNX10	16
BP	GO:0006367	transcription initiation from RNA polymerase II promoter	30/2306	188/18670	0.08427	0.2558	0.1968	PPARGC1A/WWTR1/MED10/RXRA/CCND1/E2F2/DR1/ERCC2/KAT2B/CAND1/THRA/YAP1/VDR/TAF13/PPM1D/CDK8/SUB1/MED8/TAF7L/GTF2H5/TAF6L/PPARG/CDKN1A/MED20/NPPA/MNAT1/GTF2F2/CDK7/ZNF451/CBFB	30
BP	GO:1901292	nucleoside phosphate catabolic process	30/2306	188/18670	0.08427	0.2558	0.1968	PPARGC1A/SLC2A6/HK2/ENO2/ADPGK/PDE4D/NUP133/PDE1A/AMPD3/PGM2L1/NUDT18/NUDT7/ADA/ACAT1/NT5C2/ENPP1/NUDT11/NUDT1/ABCD1/PGAM4/MBD4/PDE4B/NUP35/PDE5A/IGF1/STAT3/ALDOC/P2RX7/HINT1/SIRT6	30
BP	GO:0032720	negative regulation of tumor necrosis factor production	13/2306	70/18670	0.08543	0.2589	0.1992	ZC3H12A/TNFAIP3/IRAK3/SIRPA/MC1R/ERRFI1/BCL3/AXL/AKAP8/HAVCR2/MIR125B1/GAS6/IGF1	13
BP	GO:0006942	regulation of striated muscle contraction	17/2306	97/18670	0.08545	0.2589	0.1992	ZC3H12A/GSTO1/CALM1/PDE4D/CAMK2D/DMPK/RGS2/HCN4/ADORA1/CALM2/ATP2A2/MIR1-2/PDE4B/NPPA/PDE5A/SRI/CASQ1	17
BP	GO:0010771	negative regulation of cell morphogenesis involved in differentiation	17/2306	97/18670	0.08545	0.2589	0.1992	NTN1/CORO1C/SLIT2/RUFY3/GBP1/SEMA4D/IFRD1/CDK5/WNT5A/YWHAH/TACSTD2/ACTN4/GDI1/RTN4/PPP3CA/SEMA4F/NGEF	17
BP	GO:0030316	osteoclast differentiation	17/2306	97/18670	0.08545	0.2589	0.1992	CSF1/CEBPB/MAFB/CCL3/UBASH3B/MITF/TMEM64/JUNB/FBN1/TNF/BGLAP/TFE3/TLR3/OSTM1/PIAS3/ZNF675/SNX10	17
BP	GO:0042987	amyloid precursor protein catabolic process	9/2306	44/18670	0.08589	0.2597	0.1998	IFNGR1/ROCK1/PSENEN/TNF/FKBP1A/ROCK2/TMED10/IGF1/PICALM	9
BP	GO:0046189	phenol-containing compound biosynthetic process	9/2306	44/18670	0.08589	0.2597	0.1998	SLC7A11/GCH1/MC1R/TRPC1/TGFB2/MOXD1/WNT5A/VPS35/GATA3	9
BP	GO:1902667	regulation of axon guidance	9/2306	44/18670	0.08589	0.2597	0.1998	ZSWIM4/VEGFA/SLIT2/BMPR2/SEMA4D/WNT5A/YTHDF1/SEMA4F/MYCBP2	9
BP	GO:2000404	regulation of T cell migration	9/2306	44/18670	0.08589	0.2597	0.1998	CCL20/CCL5/CXCL10/TNFRSF14/FADD/ITGA4/WNT5A/ADAM8/CRKL	9
BP	GO:0046928	regulation of neurotransmitter secretion	18/2306	104/18670	0.08636	0.261	0.2008	ADORA2A/PNKD/BACE1/RAB3GAP1/MEF2C/CDK5/RAB3A/SYT4/PREPL/PFN2/SLC30A1/DGKI/ATP2A2/STXBP1/SYT1/GRIN3A/NAPB/DVL1	18
BP	GO:0050819	negative regulation of coagulation	11/2306	57/18670	0.08693	0.2626	0.202	SERPINB2/C1QTNF1/PLAU/THBS1/UBASH3B/EDN1/MIR19B2/ABAT/PRKCD/SERPINE1/SERPINF2	11
BP	GO:0006402	mRNA catabolic process	54/2306	364/18670	0.08709	0.2629	0.2023	ZC3H12A/PSME2/PSMA6/ERN1/HSPB1/PSMB10/PSMB8/PRKCA/PSMB7/PSME1/ROCK1/TTC37/PSMB9/SET/MOV10/FTO/PSMA3/RPS3A/ZFP36/EXOSC6/ZFP36L2/CSDC2/HNRNPA0/RPL7/RPL22/PDE12/DCP1A/PSMA1/PSMB2/PABPC1/RPL37A/BTG2/SERBP1/SAMD4B/PSMB3/DDX5/EIF3E/RNH1/CNOT8/SYNCRIP/RPL15/PRKCD/PSMA8/FASTKD3/ROCK2/FXR2/UBB/LSM6/PATL1/ANGEL2/PSME4/PSMB5/PSMF1/RPS18	54
BP	GO:0055123	digestive system development	24/2306	146/18670	0.08734	0.2634	0.2027	ID2/AHI1/KIT/GIP/BMP4/OXTR/ADA/TGFB2/YIPF6/GATA6/WNT5A/TP63/CDKN1C/TNF/ASS1/PDGFC/CPS1/C1GALT1/LGR4/PRDM1/CDKN1A/FGF10/ITGA6/CRKL	24
BP	GO:2000241	regulation of reproductive process	24/2306	146/18670	0.08734	0.2634	0.2027	LIF/CITED2/BMP4/RXRA/CDC25A/MSX2/OXTR/ADA/STK4/PHLDA2/INHBB/LHFPL2/NOX5/WNT5A/NKX3-1/SULF1/ZP2/STXBP1/SPINK1/NPR2/ARHGDIB/PDE5A/IGF1/NPM2	24
BP	GO:0031333	negative regulation of protein complex assembly	23/2306	139/18670	0.08756	0.2639	0.2031	BIRC2/SLIT2/MYADM/CRYAB/RDX/THRA/DNAJC15/CLIP3/CAPZA2/VPS35/CRBN/PFN2/EPS8/GSN/STXBP1/IAPP/PRKCD/MIR214/TMOD2/PYDC2/CDC42/ZNF451/ANKRD27	23
BP	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	22/2306	132/18670	0.08765	0.2641	0.2032	BID/PRR7/DAPK1/PDCD5/FAS/ARL6IP5/MTCH1/FADD/PMAIP1/F2R/ROBO1/SIRT1/TRAF2/NKX3-1/GSN/TNF/SOX7/TNFRSF10B/BCL10/PPARG/FAM162A/ST20	22
BP	GO:0016575	histone deacetylation	14/2306	77/18670	0.08782	0.2643	0.2034	VEGFA/SAP30/CAMK2D/MORF4L2/TBL1Y/SIRT1/AKAP8/PER1/MSL3/SIN3B/TBL1XR1/SMARCAD1/TADA3/SIRT6	14
BP	GO:0051851	modification by host of symbiont morphology or physiology	14/2306	77/18670	0.08782	0.2643	0.2034	CXCL6/ZC3H12A/CCL5/CCL8/FBXL2/RAB9A/CALM1/CCL3/EIF2AK4/IGF2R/CALM2/PTX3/ZNF639/NUCKS1	14
BP	GO:0006778	porphyrin-containing compound metabolic process	8/2306	38/18670	0.08913	0.2667	0.2052	SLC11A2/NFE2L1/CYP1A2/HMOX2/ALAS1/SLC25A39/BDH2/SUCLA2	8
BP	GO:0007190	activation of adenylate cyclase activity	8/2306	38/18670	0.08913	0.2667	0.2052	P2RY11/ADCY7/ADCY9/ADCY3/CAP2/ADRB3/LGR4/ADORA3	8
BP	GO:0007223	Wnt signaling pathway, calcium modulating pathway	8/2306	38/18670	0.08913	0.2667	0.2052	MOV10/CALM1/TCF7L2/FZD2/WNT5A/FZD4/PPP3CA/GNG2	8
BP	GO:0010939	regulation of necrotic cell death	8/2306	38/18670	0.08913	0.2667	0.2052	BIRC3/BIRC2/CFLAR/PPIF/FADD/CYLD/RBCK1/MIR214	8
BP	GO:0015682	ferric iron transport	8/2306	38/18670	0.08913	0.2667	0.2052	ATP6V1E2/ATP6V0B/ATP6V0E2/CLTC/ARHGAP1/MCOLN1/STEAP2/ATP6V1E1	8
BP	GO:0015804	neutral amino acid transport	8/2306	38/18670	0.08913	0.2667	0.2052	SLC43A2/NFKBIE/SLC38A2/NFE2L1/SLC3A2/RGS2/RGS4/SLC38A1	8
BP	GO:0019068	virion assembly	8/2306	38/18670	0.08913	0.2667	0.2052	CHMP1B/CHMP4B/VPS37D/VPS37C/PPIA/CHMP5/UBB/PDCD6IP	8
BP	GO:0046676	negative regulation of insulin secretion	8/2306	38/18670	0.08913	0.2667	0.2052	IRS1/HADH/INHBB/KCNB1/SYTL4/PPP3CA/PTPN11/ADRA2A	8
BP	GO:0048009	insulin-like growth factor receptor signaling pathway	8/2306	38/18670	0.08913	0.2667	0.2052	BMP2/IRS1/CRIM1/GHR/IGF2R/NKX3-1/MIR1-2/IGF1	8
BP	GO:0071604	transforming growth factor beta production	8/2306	38/18670	0.08913	0.2667	0.2052	PTGS2/MYB/LRRC32/THBS1/TGFB2/ITGB8/GATA6/SERPINF2	8
BP	GO:0072512	trivalent inorganic cation transport	8/2306	38/18670	0.08913	0.2667	0.2052	ATP6V1E2/ATP6V0B/ATP6V0E2/CLTC/ARHGAP1/MCOLN1/STEAP2/ATP6V1E1	8
BP	GO:1901021	positive regulation of calcium ion transmembrane transporter activity	8/2306	38/18670	0.08913	0.2667	0.2052	GSTO1/CALM1/PKD2/STAC/RGN/CALM2/STIM1/CASQ1	8
BP	GO:0009166	nucleotide catabolic process	29/2306	182/18670	0.08963	0.2681	0.2063	PPARGC1A/SLC2A6/HK2/ENO2/ADPGK/PDE4D/NUP133/PDE1A/AMPD3/PGM2L1/NUDT18/NUDT7/ADA/ACAT1/NT5C2/NUDT11/NUDT1/ABCD1/PGAM4/MBD4/PDE4B/NUP35/PDE5A/IGF1/STAT3/ALDOC/P2RX7/HINT1/SIRT6	29
BP	GO:0032886	regulation of microtubule-based process	34/2306	218/18670	0.08966	0.2681	0.2063	CHMP1B/PLK2/MID1/PAK1/CHMP4B/TRIM37/CYLD/DIXDC1/CLTC/STMN3/GPSM2/DCTN1/KAT2B/PHLDB1/MAP1A/BBS2/CLIP3/CEP250/PHLDB2/RNF4/DIAPH1/CDK2AP2/CHMP5/MAPRE2/ABL1/ROCK2/MARK4/RASSF1/CNIH2/TAOK1/BICD2/MID1IP1/PDCD6IP/CAMSAP1	34
BP	GO:2000181	negative regulation of blood vessel morphogenesis	28/2306	175/18670	0.09037	0.2684	0.2065	CXCL10/THBS2/STAT1/ROCK1/PLK2/KLF2/KLF4/HSPG2/THBS1/E2F2/CARD10/TGFB2/STARD13/MEOX2/MIR19B2/SULF1/FOXJ2/MIR137/SPARC/MIR125B1/PTPRM/HLA-G/SERPINE1/ROCK2/MIR214/PDE3B/PPARG/FOXO4	28
BP	GO:0043550	regulation of lipid kinase activity	12/2306	64/18670	0.09054	0.2684	0.2065	KIT/FGF2/PDGFRB/SOCS1/SOCS3/IRS1/KLF4/PIK3R2/PIK3R3/TNFAIP8L3/SOCS2/WDR91	12
BP	GO:0046579	positive regulation of Ras protein signal transduction	12/2306	64/18670	0.09054	0.2684	0.2065	CSF1/AUTS2/PDGFRB/F2R/LPAR1/ROBO1/DGKI/MAPRE2/FGF10/IGF1/SHOC2/CRKL	12
BP	GO:0046834	lipid phosphorylation	12/2306	64/18670	0.09054	0.2684	0.2065	PIK3CD/SOCS1/SOCS3/PIK3R2/PIK3R3/IMPA2/EFR3A/DGKI/SOCS2/PIP4K2A/INPP1/PI4K2B	12
BP	GO:0048278	vesicle docking	12/2306	64/18670	0.09054	0.2684	0.2065	STX3/STX6/SCFD2/KCNB1/RAB3A/SNPH/STXBP1/SYT1/STX16/TSNARE1/PPFIA3/VPS45	12
BP	GO:0030510	regulation of BMP signaling pathway	16/2306	91/18670	0.09104	0.2684	0.2065	BMP4/GREM2/FZD1/BMPR2/MSX2/BMPER/HIPK2/GDF5/WNT5A/SULF1/HES5/FBN1/FST/ABL1/CTDSPL2/ENG	16
BP	GO:0050806	positive regulation of synaptic transmission	27/2306	168/18670	0.09106	0.2684	0.2065	PTGS2/CCL2/ADORA2A/SQSTM1/GIP/PLK2/STX3/SSH1/OXTR/EIF2AK4/RAB3GAP1/FLOT1/CDK5/RGS4/ADORA1/SNAP47/ABAT/TNF/STAU1/DLG4/STXBP1/TSHZ3/SYT1/NPTN/ABL1/YTHDF1/DVL1	27
BP	GO:0051302	regulation of cell division	27/2306	168/18670	0.09106	0.2684	0.2065	IL1B/IL1A/FGF2/VEGFA/EREG/PLK2/CALM1/LBH/TGFA/CDC14B/PDGFD/TGFB2/NKX3-1/BCL2L1/TP63/PGF/CALM2/FGF5/BIRC6/PDGFC/PKP4/KLHL13/CDK2AP2/PDXP/ZFYVE19/PKN2/CDC42	27
BP	GO:0015850	organic hydroxy compound transport	40/2306	262/18670	0.09115	0.2684	0.2065	NFKBIA/NFKB1/OSBPL10/ADORA2A/ABCA1/ATP8B1/C1QTNF1/OSBPL1A/AQP9/SLC22A1/MYB/LIMA1/RXRA/OXTR/LIPG/NISCH/AQP7/ABCA5/NPC1L1/SOAT1/SIRT1/MIR19B2/OSBPL3/ABCC2/KCNB1/SYT4/OSBPL5/ABAT/ACTB/RALBP1/SYT1/SLC22A3/TOR1A/SCP2/PPARG/PTPN11/CYP19A1/OSBPL7/ADRA2A/GRAMD1A	40
BP	GO:0002320	lymphoid progenitor cell differentiation	5/2306	20/18670	0.09115	0.2684	0.2065	KIT/BMP4/FNIP1/HES5/GATA3	5
BP	GO:0002374	cytokine secretion involved in immune response	5/2306	20/18670	0.09115	0.2684	0.2065	TNFRSF14/TNFRSF1B/WNT5A/TNF/TRIM6	5
BP	GO:0006525	arginine metabolic process	5/2306	20/18670	0.09115	0.2684	0.2065	DDAH1/FAH/ASS1/DDAH2/CPS1	5
BP	GO:0010560	positive regulation of glycoprotein biosynthetic process	5/2306	20/18670	0.09115	0.2684	0.2065	IL15/TCF7L2/SOAT1/RAMP1/IGF1	5
BP	GO:0032462	regulation of protein homooligomerization	5/2306	20/18670	0.09115	0.2684	0.2065	BID/CRYAB/VPS35/CRBN/IAPP	5
BP	GO:0032495	response to muramyl dipeptide	5/2306	20/18670	0.09115	0.2684	0.2065	NFKBIA/TNFAIP3/RIPK2/LDOC1/CHMP5	5
BP	GO:0033005	positive regulation of mast cell activation	5/2306	20/18670	0.09115	0.2684	0.2065	IL4R/SNX4/STXBP1/VAMP7/NPPA	5
BP	GO:0034393	positive regulation of smooth muscle cell apoptotic process	5/2306	20/18670	0.09115	0.2684	0.2065	SOD2/IL12A/STK4/MIR1-2/PPARG	5
BP	GO:0035458	cellular response to interferon-beta	5/2306	20/18670	0.09115	0.2684	0.2065	IRF1/STAT1/TLR3/TRIM6/CAPN2	5
BP	GO:0039529	RIG-I signaling pathway	5/2306	20/18670	0.09115	0.2684	0.2065	BIRC3/BIRC2/DDX60/DDX58/DHX58	5
BP	GO:0042228	interleukin-8 biosynthetic process	5/2306	20/18670	0.09115	0.2684	0.2065	KLF4/PRG3/BCL3/TNF/BCL10	5
BP	GO:0043586	tongue development	5/2306	20/18670	0.09115	0.2684	0.2065	KIT/SIX1/HOXC13/BNC2/SIX4	5
BP	GO:0045655	regulation of monocyte differentiation	5/2306	20/18670	0.09115	0.2684	0.2065	CDK6/CSF1/IRF7/ACIN1/MIR125B1	5
BP	GO:0050802	circadian sleep/wake cycle, sleep	5/2306	20/18670	0.09115	0.2684	0.2065	CSF2/ADORA2A/ADA/SRD5A1/ADORA1	5
BP	GO:0051580	regulation of neurotransmitter uptake	5/2306	20/18670	0.09115	0.2684	0.2065	ARL6IP5/RGS2/FLOT1/RGS4/TOR1A	5
BP	GO:0051767	nitric-oxide synthase biosynthetic process	5/2306	20/18670	0.09115	0.2684	0.2065	NAMPT/CCL2/STAT1/EDN1/AKAP12	5
BP	GO:0051769	regulation of nitric-oxide synthase biosynthetic process	5/2306	20/18670	0.09115	0.2684	0.2065	NAMPT/CCL2/STAT1/EDN1/AKAP12	5
BP	GO:0060216	definitive hemopoiesis	5/2306	20/18670	0.09115	0.2684	0.2065	MEIS1/ADAR/ZFP36L2/HOXA9/CBFB	5
BP	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	5/2306	20/18670	0.09115	0.2684	0.2065	HERPUD1/GRINA/BCL2L1/HYOU1/MAGEA3	5
BP	GO:1903204	negative regulation of oxidative stress-induced neuron death	5/2306	20/18670	0.09115	0.2684	0.2065	NCOA7/SLC7A11/FZD1/ATG7/OXR1	5
BP	GO:0001954	positive regulation of cell-matrix adhesion	10/2306	51/18670	0.09156	0.2684	0.2065	NINJ1/CDK6/CSF1/VEGFA/ROCK1/COL16A1/SDC4/ABL1/EPHA1/FERMT1	10
BP	GO:2001258	negative regulation of cation channel activity	10/2306	51/18670	0.09156	0.2684	0.2065	GSTO1/RRAD/CALM1/PKD2/ANK3/MMP9/GEM/CALM2/MIR1-2/SRI	10
BP	GO:0001975	response to amphetamine	7/2306	32/18670	0.09162	0.2684	0.2065	ICAM1/ADORA2A/OXTR/RGS2/RGS4/CNR2/PPP3CA	7
BP	GO:0035587	purinergic receptor signaling pathway	7/2306	32/18670	0.09162	0.2684	0.2065	ADORA2A/P2RY11/ADA/ADORA1/P2RX3/P2RX7/ADORA3	7
BP	GO:0045745	positive regulation of G protein-coupled receptor signaling pathway	7/2306	32/18670	0.09162	0.2684	0.2065	PRKCA/C3/FZD2/WNT5A/VPS35/MRAP2/TMOD2	7
BP	GO:0051968	positive regulation of synaptic transmission, glutamatergic	7/2306	32/18670	0.09162	0.2684	0.2065	PTGS2/CCL2/ADORA2A/OXTR/RAB3GAP1/STXBP1/TSHZ3	7
BP	GO:0055022	negative regulation of cardiac muscle tissue growth	7/2306	32/18670	0.09162	0.2684	0.2065	MEIS1/JARID2/PAK1/RGS2/RGS4/MIR1-2/MIR199A2	7
BP	GO:0060325	face morphogenesis	7/2306	32/18670	0.09162	0.2684	0.2065	ARID5B/COL1A1/RAB3GAP1/CRISPLD2/CRISPLD1/PTPN11/ANKRD11	7
BP	GO:0061117	negative regulation of heart growth	7/2306	32/18670	0.09162	0.2684	0.2065	MEIS1/JARID2/PAK1/RGS2/RGS4/MIR1-2/MIR199A2	7
BP	GO:0061311	cell surface receptor signaling pathway involved in heart development	7/2306	32/18670	0.09162	0.2684	0.2065	BMP2/BMP4/MSX2/SNAI2/MIR19B2/WNT5A/GALNT11	7
BP	GO:0090504	epiboly	7/2306	32/18670	0.09162	0.2684	0.2065	PDPN/CD44/MSX2/HBEGF/PHLDB2/TOR1A/COL5A1	7
BP	GO:1901661	quinone metabolic process	7/2306	32/18670	0.09162	0.2684	0.2065	AKR1B1/CBR3/COQ10B/CBR4/PDSS2/UBIAD1/COQ3	7
BP	GO:1902235	regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	7/2306	32/18670	0.09162	0.2684	0.2065	HERPUD1/PMAIP1/GRINA/SIRT1/BCL2L1/HYOU1/MAGEA3	7
BP	GO:1904467	regulation of tumor necrosis factor secretion	7/2306	32/18670	0.09162	0.2684	0.2065	ZC3H12A/IFIH1/IFNGR1/DDX58/AKAP12/WNT5A/HAVCR2	7
BP	GO:1902905	positive regulation of supramolecular fiber organization	32/2306	204/18670	0.09167	0.2684	0.2065	ICAM1/ARPC1A/ARHGEF10/PAK1/CDC42EP1/ACTR3/CDC42EP3/FMN2/EDN1/PXN/DSTN/DCTN1/LPAR1/FHOD1/ARPC2/ARF6/ARF1/PFN2/ARHGEF5/GSN/SH3PXD2B/MIR1-2/SDC4/GMFB/ABL1/ROCK2/PDXP/EPHA1/ACTR2/CDC42/SERPINF2/MAGEL2	32
BP	GO:0042472	inner ear morphogenesis	17/2306	98/18670	0.09206	0.2692	0.2071	LRIG1/NTN1/MAFB/SIX1/INSIG2/ALDH1A3/TTC39C/FZD2/CEP290/SIX4/WNT5A/PTK7/ATP8A2/GATA3/FGF10/DVL1/DVL2	17
BP	GO:0099175	regulation of postsynapse organization	17/2306	98/18670	0.09206	0.2692	0.2071	SIPA1L1/DBN1/CAPRIN1/SLC7A11/EEF2K/FYN/SSH1/ITPKA/CDK5/WNT5A/VPS35/BHLHB9/PDLIM5/LRFN4/ACTR2/NGEF/CRKL	17
BP	GO:0021591	ventricular system development	6/2306	26/18670	0.09272	0.27	0.2078	CDK6/SLC7A11/NME5/NUMBL/MNAT1/MYH10	6
BP	GO:0034204	lipid translocation	6/2306	26/18670	0.09272	0.27	0.2078	KCNN4/ABCA1/ATP8B1/ABCC1/ATP8A2/TMEM30B	6
BP	GO:0042481	regulation of odontogenesis	6/2306	26/18670	0.09272	0.27	0.2078	BMP2/CSF1/BMP4/EDN1/RSPO2/TNFRSF11B	6
BP	GO:0060914	heart formation	6/2306	26/18670	0.09272	0.27	0.2078	SIX1/BMP4/SMARCD3/PIM1/ROBO1/MEF2C	6
BP	GO:0071377	cellular response to glucagon stimulus	6/2306	26/18670	0.09272	0.27	0.2078	ADCY7/GJB2/ADCY9/ADCY3/ASS1/CPS1	6
BP	GO:0097066	response to thyroid hormone	6/2306	26/18670	0.09272	0.27	0.2078	AKR1B1/PPARGC1A/KIT/SIX1/CTSS/RDX	6
BP	GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	6/2306	26/18670	0.09272	0.27	0.2078	BID/PPP3CC/PMAIP1/TP63/YWHAH/TFDP1	6
BP	GO:1900740	positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	6/2306	26/18670	0.09272	0.27	0.2078	BID/PPP3CC/PMAIP1/TP63/YWHAH/TFDP1	6
BP	GO:1903203	regulation of oxidative stress-induced neuron death	6/2306	26/18670	0.09272	0.27	0.2078	NCOA7/SLC7A11/FZD1/LANCL1/ATG7/OXR1	6
BP	GO:0051495	positive regulation of cytoskeleton organization	35/2306	226/18670	0.09295	0.2706	0.2082	ICAM1/ARPC1A/ARHGEF10/PAK1/CDC42EP1/ACTR3/CDC42EP3/FMN2/EDN1/PXN/DSTN/GPSM2/DCTN1/LPAR1/FHOD1/ARPC2/CDK5/ARF6/ARF1/PFN2/ARHGEF5/GSN/SH3PXD2B/MIR1-2/SDC4/GMFB/ABL1/ROCK2/PDXP/EPHA1/ACTR2/CDC42/P2RX7/SERPINF2/MAGEL2	35
BP	GO:0042303	molting cycle	19/2306	112/18670	0.0932	0.2711	0.2085	PTGS2/LRIG1/KRT14/LDB2/HOXC13/MSX2/KRT16/ARNTL/ERCC2/TGFB2/WNT5A/TP63/TNF/FST/LGR4/PER1/KRTAP4-8/FGF10/FERMT1	19
BP	GO:0042633	hair cycle	19/2306	112/18670	0.0932	0.2711	0.2085	PTGS2/LRIG1/KRT14/LDB2/HOXC13/MSX2/KRT16/ARNTL/ERCC2/TGFB2/WNT5A/TP63/TNF/FST/LGR4/PER1/KRTAP4-8/FGF10/FERMT1	19
BP	GO:0042440	pigment metabolic process	13/2306	71/18670	0.09333	0.2712	0.2086	SLC11A2/PRPS1/PPARGC1A/SLC7A11/NFE2L1/ADA/MC1R/TRPC1/WNT5A/HMOX2/ALAS1/SLC25A39/BDH2	13
BP	GO:0071479	cellular response to ionizing radiation	13/2306	71/18670	0.09333	0.2712	0.2086	NAMPT/NET1/CYBA/CRYAB/RHOB/SNAI2/YAP1/SIRT1/BCL2L1/GATA3/GTF2H5/NUCKS1/CDKN1A	13
BP	GO:0016079	synaptic vesicle exocytosis	20/2306	119/18670	0.09343	0.2713	0.2087	ADORA2A/STX3/BACE1/RAB3GAP1/CDK5/SNAP47/RAB3A/SYT4/PREPL/PFN2/DGKI/ATP2A2/SNPH/STXBP1/SYT1/GRIN3A/NAPB/DVL1/P2RX7/PPFIA3	20
BP	GO:0009408	response to heat	28/2306	176/18670	0.09537	0.2768	0.213	PTGS2/CXCL10/IL1A/BAG2/ST8SIA1/DAXX/MYOF/DNAJA1/RPA2/CAMK2D/NUP133/THBS1/CRYAB/TP53INP1/LRP11/STAC/SIRT1/ABCC2/MICB/P2RX3/CAMK2G/ATP2A2/EIF2B5/EIF2B4/CDKN1A/NUP35/IGF1/CASQ1	28
BP	GO:0090398	cellular senescence	14/2306	78/18670	0.09546	0.277	0.2131	NAMPT/ID2/CDK6/PLK2/ARNTL/NUAK1/NSMCE2/SIRT1/NEK6/PRKCD/HLA-G/ABL1/CDKN1A/TBX3	14
BP	GO:0006949	syncytium formation	11/2306	58/18670	0.0959	0.2778	0.2138	CXCL10/MYOF/CFLAR/IL4R/CXCL9/FLOT1/EHD1/PLEKHO1/GDF15/MYH9/CAPN2	11
BP	GO:0032722	positive regulation of chemokine production	11/2306	58/18670	0.0959	0.2778	0.2138	IL6/IL1B/RIPK2/IL33/IL4R/MBP/WNT5A/HAVCR2/TNF/TLR3/TICAM1	11
BP	GO:0061951	establishment of protein localization to plasma membrane	11/2306	58/18670	0.0959	0.2778	0.2138	SYS1/ANK3/BBS2/OPTN/VPS35/PREPL/VAMP7/RILPL1/RAB31/GRIPAP1/VAMP5	11
BP	GO:0031018	endocrine pancreas development	9/2306	45/18670	0.09618	0.2782	0.214	IL6/CDK6/FOXO1/GIP/BMP4/NEUROG3/ARNTL/GATA6/WNT5A	9
BP	GO:0050728	negative regulation of inflammatory response	27/2306	169/18670	0.0962	0.2782	0.214	ZC3H12A/TNFAIP3/TNFAIP6/NFKB1/ADORA2A/TNFRSF1B/SOCS3/ETS1/KLF4/ADA/SIRPA/ADCY7/PSMA1/ABCD1/SIGLEC10/ADORA1/VPS35/SLAMF8/APPL2/CNR2/GATA3/PRKCD/DUSP10/PPARG/PYDC2/IGF1/CYP19A1	27
BP	GO:0051100	negative regulation of binding	27/2306	169/18670	0.0962	0.2782	0.214	NFKBIA/ID2/BAG2/DAB2/ROCK1/IFIT1/ZFP90/PIM2/ARHGAP28/ITGA4/MSX2/CSNK1E/CARM1/NKX3-1/IFIT2/ACTB/SUMO3/SP100/PRKCD/CRMP1/PPP3CA/MITD1/ID3/MEPCE/DVL1/SRI/ZNF675	27
BP	GO:0006164	purine nucleotide biosynthetic process	45/2306	300/18670	0.0962	0.2782	0.214	PID1/PRPS1/PPARGC1A/SLC2A6/MTHFD2L/HK2/PRPS1L1/ACACB/ELOVL5/ENO2/ADPGK/NUP133/AK1/SCD/ELOVL7/AMPD3/PGM2L1/ADA/ACAT1/PPT1/ADCY7/ACACA/NME5/ACSL5/CBR4/ADCY9/ADCY3/ELOVL2/IMPDH2/PPCS/HSD17B12/PDHB/PAPSS1/GUK1/PGAM4/NPR2/PDK3/NPPA/NUP35/IGF1/STAT3/ALDOC/P2RX7/SIRT6/ELOVL3	45
BP	GO:0009100	glycoprotein metabolic process	61/2306	419/18670	0.09644	0.2788	0.2145	BMP2/GFPT2/TNIP1/ST3GAL1/ST8SIA1/BACE2/MAN1A1/PHLDA1/B4GALT3/BMPR2/VCAN/GALNT10/CHST7/MAN1C1/A4GALT/GNPTAB/IL15/SULF2/TET1/NCCRP1/TCF7L2/CYTL1/GXYLT1/HBEGF/SERP2/CSGALNACT1/SOAT1/CSGALNACT2/MOGS/POMGNT1/RNF5/SULF1/RAMP1/PGM3/GALNT5/MGAT1/MGAT2/GCNT1/TET3/CHST8/PTX3/AGA/C1GALT1/EXT1/ST3GAL3/ALG3/FBXO17/HS2ST1/GALNT4/ACOT8/DAD1/DPY19L4/MUC15/MUC17/IGF1/ALG13/GALNT11/GALNT1/SLC35C1/TMEM165/ST3GAL4	61
BP	GO:0007187	G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	39/2306	256/18670	0.09656	0.279	0.2146	GPR37L1/S1PR3/CXCL10/CCL2/ADORA2A/ABCA1/NPR3/PRKCA/PTGFR/PDE4D/CXCL11/EDN1/PTGER2/AKAP12/PTHLH/CXCL9/ADM2/MC1R/ADCY7/RGS2/LPAR1/GNA13/ADCY9/ADCY3/GNA12/ARRDC3/ADORA1/RAMP1/MRAP2/GPR161/MIR1-2/CNR2/IAPP/ADRB3/GRM2/LGR4/ADRA2A/WASF2/GNG2	39
BP	GO:0030833	regulation of actin filament polymerization	26/2306	162/18670	0.09697	0.2799	0.2153	ICAM1/ARPC1A/DBN1/CDC42EP1/ARHGAP18/ACTR3/CDC42EP3/SLIT2/MYADM/ARHGAP28/FMN2/RDX/ARPC2/CAPZA2/ARF6/ARF1/PFN2/EPS8/GSN/PRKCD/GMFB/MIR214/ACTR2/TMOD2/PLEKHG2/MAGEL2	26
BP	GO:0034308	primary alcohol metabolic process	15/2306	85/18670	0.09704	0.2799	0.2153	BMP2/AKR1B1/ALDH1A3/CYP27C1/RDH10/RDH8/DHRS3/ADH5/CYP1A2/CBR4/SULT1C4/PECR/RDH13/ADH1C/IGF1	15
BP	GO:1904705	regulation of vascular smooth muscle cell proliferation	15/2306	85/18670	0.09704	0.2799	0.2153	SOD2/ERN1/FGF2/PAK1/EDN1/MMP9/MEF2C/FOXJ2/MIR137/TNF/MIR1-2/MIR214/PPARG/CDKN1A/IGF1	15
BP	GO:1990874	vascular smooth muscle cell proliferation	15/2306	85/18670	0.09704	0.2799	0.2153	SOD2/ERN1/FGF2/PAK1/EDN1/MMP9/MEF2C/FOXJ2/MIR137/TNF/MIR1-2/MIR214/PPARG/CDKN1A/IGF1	15
BP	GO:0031099	regeneration	31/2306	198/18670	0.09742	0.2808	0.2161	CLDN1/NINJ1/LPIN1/CEBPB/CFLAR/JAM3/CCND1/KLF4/SULF2/NNMT/YAP1/IGF2R/IFRD1/AXL/AKIRIN1/RGN/MTR/TNC/GSN/PGF/BIN3/NINJ2/PPP3CA/DUSP10/GAS6/PPARG/CDKN1A/FGF10/MIR199A2/IGF1/FZD7	31
BP	GO:1901861	regulation of muscle tissue development	25/2306	155/18670	0.09767	0.2814	0.2165	BMP2/PPARGC1A/FGF2/MEIS1/JARID2/SIX1/BMP4/PAK1/PIM1/EDN1/ARNTL/RGS2/GATA6/YAP1/FLOT1/SIX4/MEF2C/AKIRIN1/MIR19B2/RGS4/DDX5/MIR1-2/MIR199A2/IGF1/FZD7	25
BP	GO:0045833	negative regulation of lipid metabolic process	16/2306	92/18670	0.09819	0.2828	0.2176	BMP2/IL1B/NFKB1/INSIG2/ACACB/TRIB3/CYP27B1/SNAI2/SIRT1/ADORA1/TNF/APPL2/PDE3B/SIK1/ADRA2A/CRTC3	16
BP	GO:0072527	pyrimidine-containing compound metabolic process	17/2306	99/18670	0.09898	0.2849	0.2192	PRPS1/TYMP/APOBEC3G/CMPK2/TET1/APOBEC3H/SLC19A3/NME5/CDADC1/TET3/GPAM/CPS1/APOBEC3F/MBD4/TK2/DCK/LCLAT1	17
BP	GO:0060389	pathway-restricted SMAD protein phosphorylation	12/2306	65/18670	0.09919	0.2849	0.2192	BMP2/DAB2/BMP4/BMPR2/BMPER/INHBB/SDCBP/TGFB2/GDF5/GDF15/ENG/GDF6	12
BP	GO:0030260	entry into host cell	22/2306	134/18670	0.09926	0.2849	0.2192	ICAM1/CLDN1/ANPEP/XPR1/IFITM1/TNFRSF14/SLC20A2/TRIM25/EPS15/ITGB5/ITCH/ITGA2/PPIA/KPNA3/AXL/TRIM21/GSN/PTX3/ZNF639/GAS6/TRIM38/SNX3	22
BP	GO:0044409	entry into host	22/2306	134/18670	0.09926	0.2849	0.2192	ICAM1/CLDN1/ANPEP/XPR1/IFITM1/TNFRSF14/SLC20A2/TRIM25/EPS15/ITGB5/ITCH/ITGA2/PPIA/KPNA3/AXL/TRIM21/GSN/PTX3/ZNF639/GAS6/TRIM38/SNX3	22
BP	GO:0048565	digestive tract development	22/2306	134/18670	0.09926	0.2849	0.2192	ID2/AHI1/KIT/BMP4/OXTR/ADA/TGFB2/YIPF6/GATA6/WNT5A/TP63/TNF/ASS1/PDGFC/CPS1/C1GALT1/LGR4/PRDM1/CDKN1A/FGF10/ITGA6/CRKL	22
BP	GO:0051806	entry into cell of other organism involved in symbiotic interaction	22/2306	134/18670	0.09926	0.2849	0.2192	ICAM1/CLDN1/ANPEP/XPR1/IFITM1/TNFRSF14/SLC20A2/TRIM25/EPS15/ITGB5/ITCH/ITGA2/PPIA/KPNA3/AXL/TRIM21/GSN/PTX3/ZNF639/GAS6/TRIM38/SNX3	22
BP	GO:0051828	entry into other organism involved in symbiotic interaction	22/2306	134/18670	0.09926	0.2849	0.2192	ICAM1/CLDN1/ANPEP/XPR1/IFITM1/TNFRSF14/SLC20A2/TRIM25/EPS15/ITGB5/ITCH/ITGA2/PPIA/KPNA3/AXL/TRIM21/GSN/PTX3/ZNF639/GAS6/TRIM38/SNX3	22
BP	GO:0048639	positive regulation of developmental growth	29/2306	184/18670	0.09954	0.2856	0.2197	CSF1/NTN1/BASP1/FGF2/ZFYVE27/DBN1/VEGFA/PAK1/ACACB/BMPR2/RUFY3/PIM1/EDN1/GHR/SEMA4D/GATA6/BBS2/YAP1/MEF2C/MIR19B2/SYT4/SH3PXD2B/ATP8A2/GDI1/SYT1/MIR199A2/IGF1/CDH4/SASH3	29
BP	GO:0030501	positive regulation of bone mineralization	8/2306	39/18670	0.1006	0.2874	0.2211	BMP2/ISG15/BMP4/BMPR2/MEF2C/OSR2/OSR1/P2RX7	8
BP	GO:0035886	vascular smooth muscle cell differentiation	8/2306	39/18670	0.1006	0.2874	0.2211	SOD2/KIT/VEGFA/GATA6/MIR1-2/MIR125B1/ENG/SGCB	8
BP	GO:0043001	Golgi to plasma membrane protein transport	8/2306	39/18670	0.1006	0.2874	0.2211	SYS1/ANK3/BBS2/OPTN/PREPL/VAMP7/RAB31/VAMP5	8
BP	GO:0050775	positive regulation of dendrite morphogenesis	8/2306	39/18670	0.1006	0.2874	0.2211	DBN1/CAPRIN1/EEF2K/ITPKA/BHLHB9/VAMP7/ACTR2/ANKRD27	8
BP	GO:0050856	regulation of T cell receptor signaling pathway	8/2306	39/18670	0.1006	0.2874	0.2211	KCNN4/GBP1/CYLD/ADA/DUSP3/CACNA1F/PVRIG/BCL10	8
BP	GO:0072529	pyrimidine-containing compound catabolic process	8/2306	39/18670	0.1006	0.2874	0.2211	TYMP/APOBEC3G/TET1/APOBEC3H/CDADC1/TET3/APOBEC3F/MBD4	8
BP	GO:1904591	positive regulation of protein import	8/2306	39/18670	0.1006	0.2874	0.2211	ZC3H12A/PTGS2/PDCD5/PIK3R2/UBR5/ARHGEF5/PRKCD/CHP2	8
BP	GO:1905521	regulation of macrophage migration	8/2306	39/18670	0.1006	0.2874	0.2211	CCL5/CSF1/CMKLR1/CCL3/THBS1/AKIRIN1/SLAMF8/CYP19A1	8
BP	GO:2000826	regulation of heart morphogenesis	8/2306	39/18670	0.1006	0.2874	0.2211	BMP2/SIX1/BMP4/BMPR2/PIM1/TGFB2/ROBO1/ENG	8
BP	GO:0006998	nuclear envelope organization	10/2306	52/18670	0.1015	0.2896	0.2228	LPIN1/PRKCA/CHMP4B/LMNA/DMPK/DCTN1/NEK6/PARP11/ANKLE2/TOR1A	10
BP	GO:0031529	ruffle organization	10/2306	52/18670	0.1015	0.2896	0.2228	ICAM1/CORO1C/LIMA1/RDX/ARF6/PFN2/EPS8/TACSTD2/SH3YL1/SNX10	10
BP	GO:0050805	negative regulation of synaptic transmission	13/2306	72/18670	0.1017	0.2899	0.2231	PTGS2/IL1B/PLK2/PNKD/ADORA1/KCNB1/SYT4/ARF1/SLC30A1/DGKI/CNR2/STXBP1/PCDH17	13
BP	GO:1903556	negative regulation of tumor necrosis factor superfamily cytokine production	13/2306	72/18670	0.1017	0.2899	0.2231	ZC3H12A/TNFAIP3/IRAK3/SIRPA/MC1R/ERRFI1/BCL3/AXL/AKAP8/HAVCR2/MIR125B1/GAS6/IGF1	13
BP	GO:0006914	autophagy	71/2306	496/18670	0.1023	0.2916	0.2243	ZC3H12A/NAMPT/RIPK2/RAB23/ERN1/HSPB1/DRAM1/PPARGC1A/SQSTM1/FBXL2/FNBP1L/FOXO1/DAPK1/SESN1/GABARAPL1/KLHL3/TP53INP2/HK2/ROCK1/PLK2/ATP6V1E2/PLEKHF1/ATP6V0B/PIM2/CHMP4B/NRBP2/ATP6V0E2/WIPI1/PIK3R2/TRIB3/EIF2AK4/RAB3GAP1/VPS37D/SH3BP4/CLTC/VPS36/VPS37C/TP53INP1/SESN3/RNF5/CDK5/SIRT1/OPTN/ATG7/VPS35/TRIM21/TPCN1/CAMKK2/SESN2/PAFAH1B2/DYNLL1/TMEM208/PRKAB2/ABL1/WDR45/LGALS8/VDAC1/POLDIP2/SBF2/MCOLN1/PACS2/PIP4K2A/FEZ2/TICAM1/ATP13A2/MIR199A2/STAT3/NEDD4/ATP6V1E1/VPS26A/OSBPL7	71
BP	GO:0061919	process utilizing autophagic mechanism	71/2306	496/18670	0.1023	0.2916	0.2243	ZC3H12A/NAMPT/RIPK2/RAB23/ERN1/HSPB1/DRAM1/PPARGC1A/SQSTM1/FBXL2/FNBP1L/FOXO1/DAPK1/SESN1/GABARAPL1/KLHL3/TP53INP2/HK2/ROCK1/PLK2/ATP6V1E2/PLEKHF1/ATP6V0B/PIM2/CHMP4B/NRBP2/ATP6V0E2/WIPI1/PIK3R2/TRIB3/EIF2AK4/RAB3GAP1/VPS37D/SH3BP4/CLTC/VPS36/VPS37C/TP53INP1/SESN3/RNF5/CDK5/SIRT1/OPTN/ATG7/VPS35/TRIM21/TPCN1/CAMKK2/SESN2/PAFAH1B2/DYNLL1/TMEM208/PRKAB2/ABL1/WDR45/LGALS8/VDAC1/POLDIP2/SBF2/MCOLN1/PACS2/PIP4K2A/FEZ2/TICAM1/ATP13A2/MIR199A2/STAT3/NEDD4/ATP6V1E1/VPS26A/OSBPL7	71
BP	GO:0045931	positive regulation of mitotic cell cycle	26/2306	163/18670	0.1024	0.2918	0.2245	IL1B/IL1A/PRKCA/EREG/PDGFRB/CCND1/CDC25A/SMARCD3/EDN1/RDX/TGFA/DUSP3/LRP5/NSMCE2/NKX3-1/ASNS/ABL1/MIR214/POLDIP2/PTPN11/FGF10/PKN2/SH2B1/MEPCE/IGF1/DYNLT3	26
BP	GO:0021675	nerve development	14/2306	79/18670	0.1035	0.2935	0.2258	LRIG1/VCAM1/ATP8B1/MAFB/SIX1/ITGA4/NAV2/SULF2/LPAR1/SIX4/SULF1/HES3/HOXD3/ADARB1	14
BP	GO:0002716	negative regulation of natural killer cell mediated immunity	4/2306	15/18670	0.1041	0.2935	0.2258	HLA-E/HLA-F/HAVCR2/HLA-G	4
BP	GO:0007216	G protein-coupled glutamate receptor signaling pathway	4/2306	15/18670	0.1041	0.2935	0.2258	DAGLA/DAGLB/GRM2/HOMER2	4
BP	GO:0015936	coenzyme A metabolic process	4/2306	15/18670	0.1041	0.2935	0.2258	NUDT7/CROT/ACAT1/PPCS	4
BP	GO:0017014	protein nitrosylation	4/2306	15/18670	0.1041	0.2935	0.2258	NCOA7/ADH5/SNTA1/OXR1	4
BP	GO:0018119	peptidyl-cysteine S-nitrosylation	4/2306	15/18670	0.1041	0.2935	0.2258	NCOA7/ADH5/SNTA1/OXR1	4
BP	GO:0032736	positive regulation of interleukin-13 production	4/2306	15/18670	0.1041	0.2935	0.2258	IL33/HLA-E/IL17RB/GATA3	4
BP	GO:0034134	toll-like receptor 2 signaling pathway	4/2306	15/18670	0.1041	0.2935	0.2258	TNFAIP3/RIPK2/CYBA/PJA2	4
BP	GO:0043584	nose development	4/2306	15/18670	0.1041	0.2935	0.2258	SIX1/ALDH1A3/RDH10/SIX4	4
BP	GO:0045410	positive regulation of interleukin-6 biosynthetic process	4/2306	15/18670	0.1041	0.2935	0.2258	IL1B/EREG/TNF/STAT3	4
BP	GO:0048172	regulation of short-term neuronal synaptic plasticity	4/2306	15/18670	0.1041	0.2935	0.2258	RAB3GAP1/RAB3A/SYT4/PPFIA3	4
BP	GO:0048569	post-embryonic animal organ development	4/2306	15/18670	0.1041	0.2935	0.2258	VEGFA/KLF4/MYO1E/FBN1	4
BP	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	4/2306	15/18670	0.1041	0.2935	0.2258	NAMPT/CCL2/STAT1/AKAP12	4
BP	GO:0060026	convergent extension	4/2306	15/18670	0.1041	0.2935	0.2258	WNT5A/PTK7/DVL1/DVL2	4
BP	GO:0060134	prepulse inhibition	4/2306	15/18670	0.1041	0.2935	0.2258	ADORA2A/BACE1/GRIN3A/DVL1	4
BP	GO:0090136	epithelial cell-cell adhesion	4/2306	15/18670	0.1041	0.2935	0.2258	SERPINB8/KIT/VCL/ITGB5	4
BP	GO:0090197	positive regulation of chemokine secretion	4/2306	15/18670	0.1041	0.2935	0.2258	IL33/IL4R/MBP/TNF	4
BP	GO:1903543	positive regulation of exosomal secretion	4/2306	15/18670	0.1041	0.2935	0.2258	SDCBP/SDC4/ATP13A2/PDCD6IP	4
BP	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway	4/2306	15/18670	0.1041	0.2935	0.2258	DAB2/ANKRD6/ABL1/PLEKHA4	4
BP	GO:2001256	regulation of store-operated calcium entry	4/2306	15/18670	0.1041	0.2935	0.2258	STIM1/SPINK1/CASQ1/HOMER2	4
BP	GO:2001056	positive regulation of cysteine-type endopeptidase activity	24/2306	149/18670	0.1041	0.2935	0.2258	BID/RIPK2/PRR7/DAPK1/PDCD5/FYN/FAS/ARL6IP5/MTCH1/FADD/PMAIP1/F2R/ROBO1/SIRT1/TRAF2/NKX3-1/GSN/TNF/SOX7/TNFRSF10B/BCL10/PPARG/FAM162A/ST20	24
BP	GO:0006471	protein ADP-ribosylation	7/2306	33/18670	0.1045	0.2935	0.2258	PARP12/PARP14/KAT2B/PARP9/PARP11/PARP15/SIRT6	7
BP	GO:0010737	protein kinase A signaling	7/2306	33/18670	0.1045	0.2935	0.2258	RAB13/AKAP12/RDX/MYOM1/MC1R/IAPP/PJA2	7
BP	GO:0010837	regulation of keratinocyte proliferation	7/2306	33/18670	0.1045	0.2935	0.2258	ZFP36/SNAI2/YAP1/HAS2/VDR/TP63/FGF10	7
BP	GO:0019692	deoxyribose phosphate metabolic process	7/2306	33/18670	0.1045	0.2935	0.2258	CMPK2/NUDT18/ADA/NUDT1/CDADC1/GUK1/MBD4	7
BP	GO:0030513	positive regulation of BMP signaling pathway	7/2306	33/18670	0.1045	0.2935	0.2258	BMP4/BMPR2/MSX2/GDF5/SULF1/HES5/ENG	7
BP	GO:0032633	interleukin-4 production	7/2306	33/18670	0.1045	0.2935	0.2258	CD83/IL33/CEBPB/HLA-E/HAVCR2/GATA3/SASH3	7
BP	GO:0046633	alpha-beta T cell proliferation	7/2306	33/18670	0.1045	0.2935	0.2258	RIPK2/SH3RF1/IRF1/TNFRSF14/HLA-E/IL15/EBI3	7
BP	GO:0051443	positive regulation of ubiquitin-protein transferase activity	7/2306	33/18670	0.1045	0.2935	0.2258	TRIB3/CDC14B/ARRDC4/ARRDC3/DCUN1D4/TOPORS/UBE2S	7
BP	GO:0071985	multivesicular body sorting pathway	7/2306	33/18670	0.1045	0.2935	0.2258	CHMP1B/SORT1/VPS37D/VPS36/VPS37C/SYTL4/CHMP5	7
BP	GO:2000758	positive regulation of peptidyl-lysine acetylation	7/2306	33/18670	0.1045	0.2935	0.2258	IL1B/LIF/PPARGC1A/AUTS2/SNAI2/RPS6KA4/GATA3	7
BP	GO:0003333	amino acid transmembrane transport	15/2306	86/18670	0.1048	0.294	0.2262	SLC7A2/SLC43A2/PDPN/SLC7A11/SLC38A2/ARL6IP5/SLC3A2/RGS2/LRRC8E/RGS4/SLC38A4/CLN8/SLC38A6/OSR1/SLC38A1	15
BP	GO:0030101	natural killer cell activation	15/2306	86/18670	0.1048	0.294	0.2262	ID2/PIK3CD/HLA-E/IL12A/IL18R1/HLA-F/IL15/AXL/MICB/HAVCR2/NCR1/PRDM1/GAS6/VAMP7/TICAM1	15
BP	GO:0042130	negative regulation of T cell proliferation	11/2306	59/18670	0.1054	0.2953	0.2272	CEBPB/TNFRSF14/PDCD1LG2/IDO1/BMP4/LRRC32/MAD1L1/HAVCR2/HLA-G/SDC4/PDE5A	11
BP	GO:0043388	positive regulation of DNA binding	11/2306	59/18670	0.1054	0.2953	0.2272	KLF4/EDF1/HIPK2/ERCC2/ITGA2/MMP9/TXN/TRIM6/GATA3/PPARG/IGF1	11
BP	GO:1903322	positive regulation of protein modification by small protein conjugation or removal	22/2306	135/18670	0.1054	0.2953	0.2272	BIRC3/ZC3H12A/TNIP1/RIPK2/BIRC2/RNF20/NDFIP1/TRIB3/CDC14B/ARRDC4/GNL3/ARRDC3/DCUN1D4/TOPORS/FKBP1A/BCL10/UBB/NDFIP2/TICAM1/MYCBP2/PIAS3/UBE2S	22
BP	GO:0003073	regulation of systemic arterial blood pressure	16/2306	93/18670	0.1057	0.2959	0.2277	SOD2/GPR37L1/DDAH1/PDE4D/NR2F2/BMPR2/CYBA/OXTR/NAV2/EDN1/F2R/ADORA1/ADRB3/GAS6/NPPA/SERPINF2	16
BP	GO:0006643	membrane lipid metabolic process	32/2306	207/18670	0.1061	0.2962	0.2279	KIT/ST8SIA1/TEX2/ESYT1/ELOVL5/B4GALT3/UGCG/PIGV/ELOVL7/A4GALT/NAGA/GLA/GLB1/PPT1/ITGB8/CSNK1G2/ELOVL2/UGT8/TNF/CLN8/ALDH5A1/MPPE1/PRKCD/SGMS2/PIGK/PIGS/NSMAF/MGST2/P2RX7/SAMD8/ELOVL3/ST3GAL4	32
BP	GO:0030330	DNA damage response, signal transduction by p53 class mediator	18/2306	107/18670	0.1065	0.2962	0.2279	PLK2/CD44/PRMT1/PMAIP1/HIPK2/SNAI2/CARM1/BCL3/SIRT1/BTG2/SESN2/DDX5/ARID3A/PPM1D/CNOT8/SP100/CDKN1A/TFDP1	18
BP	GO:0048524	positive regulation of viral process	18/2306	107/18670	0.1065	0.2962	0.2279	CCL5/IFIT1/CHMP4B/ADAR/PPIA/PDE12/IGF2R/PABPC1/TRIM21/RAD23A/STAU1/ADARB1/ZNF639/NUCKS1/KPNA2/PKN2/TRIM38/GTF2F2	18
BP	GO:0050905	neuromuscular process	18/2306	107/18670	0.1065	0.2962	0.2279	ADORA2A/ALDH1A3/CNTNAP1/PNKD/BACE1/GCH1/NPAS1/DCTN1/CLN8/DLG4/ATP8A2/ADARB1/GRIN3A/ABL1/PCDH15/MYH10/DVL1/MYCBP2	18
BP	GO:0062014	negative regulation of small molecule metabolic process	18/2306	107/18670	0.1065	0.2962	0.2279	BMP2/PID1/NFKB1/PPARGC1A/INSIG2/ACACB/PPIF/TRIB3/CYP27B1/CLTC/SNAI2/PDE12/DNAJC15/SIRT1/APPL2/SIK1/STAT3/SIRT6	18
BP	GO:0008543	fibroblast growth factor receptor signaling pathway	19/2306	114/18670	0.1065	0.2962	0.2279	FGF2/THBS1/SULF2/FGFRL1/SPRY1/FLRT2/WNT5A/SULF1/SHISA2/FLRT3/MIR1-2/FGF5/GATA3/NPTN/PTPN11/FGF10/SHOC2/GTF2F2/CRKL	19
BP	GO:0010633	negative regulation of epithelial cell migration	19/2306	114/18670	0.1065	0.2962	0.2279	FGF2/MCC/CORO1C/SLIT2/NR2F2/KLF4/THBS1/CARD10/STARD13/MEOX2/MEF2C/MIR19B2/PFN2/MIR137/TACSTD2/PTPRM/SP100/DUSP10/PPARG	19
BP	GO:0005978	glycogen biosynthetic process	9/2306	46/18670	0.1071	0.2962	0.2279	PPP1R3F/UGP2/IRS1/PGM2L1/DYRK2/ENPP1/GYG1/GYS2/IGF1	9
BP	GO:0009250	glucan biosynthetic process	9/2306	46/18670	0.1071	0.2962	0.2279	PPP1R3F/UGP2/IRS1/PGM2L1/DYRK2/ENPP1/GYG1/GYS2/IGF1	9
BP	GO:0031648	protein destabilization	9/2306	46/18670	0.1071	0.2962	0.2279	BMP2/RNF5/SIRT1/VPS35/TRIM21/RAD23A/GSN/MYLIP/SIRT6	9
BP	GO:1900015	regulation of cytokine production involved in inflammatory response	9/2306	46/18670	0.1071	0.2962	0.2279	ZC3H12A/GBP5/SIRPA/ADCY7/ABCD1/APPL2/BAP1/PER1/TICAM1	9
BP	GO:1904036	negative regulation of epithelial cell apoptotic process	9/2306	46/18670	0.1071	0.2962	0.2279	ICAM1/TNFAIP3/CFLAR/TCF7L2/CAST/GATA3/SERPINE1/ABL1/GAS6	9
BP	GO:0002825	regulation of T-helper 1 type immune response	6/2306	27/18670	0.1074	0.2962	0.2279	IL1B/RIPK2/IL33/IL18R1/IL4R/HAVCR2	6
BP	GO:0006829	zinc ion transport	6/2306	27/18670	0.1074	0.2962	0.2279	SLC39A14/SLC39A10/SLC39A8/SLC30A9/SLC30A7/SLC30A1	6
BP	GO:0036336	dendritic cell migration	6/2306	27/18670	0.1074	0.2962	0.2279	CCL5/IL12A/ARHGEF5/EPS8/SLAMF8/GAS6	6
BP	GO:0036475	neuron death in response to oxidative stress	6/2306	27/18670	0.1074	0.2962	0.2279	NCOA7/SLC7A11/FZD1/LANCL1/ATG7/OXR1	6
BP	GO:0048143	astrocyte activation	6/2306	27/18670	0.1074	0.2962	0.2279	IL6/IL1B/ADORA2A/IFNGR1/BACE2/TNF	6
BP	GO:0060143	positive regulation of syncytium formation by plasma membrane fusion	6/2306	27/18670	0.1074	0.2962	0.2279	IL4R/CXCL9/FLOT1/EHD1/GDF15/CAPN2	6
BP	GO:0060384	innervation	6/2306	27/18670	0.1074	0.2962	0.2279	LRIG1/VCAM1/ITGA4/SULF2/SULF1/ADARB1	6
BP	GO:0061437	renal system vasculature development	6/2306	27/18670	0.1074	0.2962	0.2279	CFLAR/BMP4/PDGFRB/PKD2/PDGFD/OSR1	6
BP	GO:0061440	kidney vasculature development	6/2306	27/18670	0.1074	0.2962	0.2279	CFLAR/BMP4/PDGFRB/PKD2/PDGFD/OSR1	6
BP	GO:0071450	cellular response to oxygen radical	6/2306	27/18670	0.1074	0.2962	0.2279	SOD2/GCH1/RGN/ADPRHL2/TNF/GLRX2	6
BP	GO:0071451	cellular response to superoxide	6/2306	27/18670	0.1074	0.2962	0.2279	SOD2/GCH1/RGN/ADPRHL2/TNF/GLRX2	6
BP	GO:1901623	regulation of lymphocyte chemotaxis	6/2306	27/18670	0.1074	0.2962	0.2279	CCL5/CXCL10/CCL2/CCL7/CCL3/WNT5A	6
BP	GO:1905208	negative regulation of cardiocyte differentiation	6/2306	27/18670	0.1074	0.2962	0.2279	BMP2/PAK1/RGS2/RGS4/MIR199A2/FZD7	6
BP	GO:0098656	anion transmembrane transport	43/2306	288/18670	0.1075	0.2962	0.2279	SLC7A2/SLC43A2/ABCA1/PDPN/XPR1/SLC7A11/AQP9/SLC20A2/SLC38A2/ACACB/CLIC6/ARL6IP5/THBS1/SLC12A2/SLC3A2/PCYOX1/SLC35A1/CPT1A/CLIC3/CLCNKA/ACACA/RGS2/ABCC1/LRRC8E/RGS4/SLC38A4/SLC25A20/CLN8/PRKAB2/GABRA3/SLC38A6/VDAC1/SLC26A3/SLC19A1/SLC35B4/SLC35B1/CLDN17/OSR1/SLC37A1/CLCA1/SLC38A1/MID1IP1/SLC9A9	43
BP	GO:0001956	positive regulation of neurotransmitter secretion	5/2306	21/18670	0.108	0.2962	0.2279	ADORA2A/RAB3GAP1/CDK5/STXBP1/SYT1	5
BP	GO:0002115	store-operated calcium entry	5/2306	21/18670	0.108	0.2962	0.2279	STIM1/SPINK1/ORAI1/CASQ1/HOMER2	5
BP	GO:0006907	pinocytosis	5/2306	21/18670	0.108	0.2962	0.2279	EHD4/PPT1/AXL/APPL2/ACTN4	5
BP	GO:0009081	branched-chain amino acid metabolic process	5/2306	21/18670	0.108	0.2962	0.2279	HIBCH/BCKDHB/ACAT1/HIBADH/BCAT2	5
BP	GO:0009083	branched-chain amino acid catabolic process	5/2306	21/18670	0.108	0.2962	0.2279	HIBCH/BCKDHB/ACAT1/HIBADH/BCAT2	5
BP	GO:0009713	catechol-containing compound biosynthetic process	5/2306	21/18670	0.108	0.2962	0.2279	GCH1/TGFB2/MOXD1/VPS35/GATA3	5
BP	GO:0016553	base conversion or substitution editing	5/2306	21/18670	0.108	0.2962	0.2279	APOBEC3G/ADAR/APOBEC3H/ADARB1/APOBEC3F	5
BP	GO:0031498	chromatin disassembly	5/2306	21/18670	0.108	0.2962	0.2279	SET/SMARCD3/ARID1A/PBRM1/SMARCE1	5
BP	GO:0032986	protein-DNA complex disassembly	5/2306	21/18670	0.108	0.2962	0.2279	SET/SMARCD3/ARID1A/PBRM1/SMARCE1	5
BP	GO:0036499	PERK-mediated unfolded protein response	5/2306	21/18670	0.108	0.2962	0.2279	CCL2/PPP1R15A/HERPUD1/ASNS/TMEM33	5
BP	GO:0039531	regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway	5/2306	21/18670	0.108	0.2962	0.2279	BIRC3/BIRC2/DDX60/TSPAN6/DHX58	5
BP	GO:0039702	viral budding via host ESCRT complex	5/2306	21/18670	0.108	0.2962	0.2279	CHMP1B/CHMP4B/VPS37D/VPS37C/PDCD6IP	5
BP	GO:0042135	neurotransmitter catabolic process	5/2306	21/18670	0.108	0.2962	0.2279	HNMT/AMT/ALDH7A1/ABAT/ALDH5A1	5
BP	GO:0042423	catecholamine biosynthetic process	5/2306	21/18670	0.108	0.2962	0.2279	GCH1/TGFB2/MOXD1/VPS35/GATA3	5
BP	GO:0070584	mitochondrion morphogenesis	5/2306	21/18670	0.108	0.2962	0.2279	PID1/BCL2L1/NUBPL/POLDIP2/POLG2	5
BP	GO:0070920	regulation of production of small RNA involved in gene silencing by RNA	5/2306	21/18670	0.108	0.2962	0.2279	ZC3H12A/BMP4/DDX5/PPP3CA/NCOR2	5
BP	GO:1900016	negative regulation of cytokine production involved in inflammatory response	5/2306	21/18670	0.108	0.2962	0.2279	ZC3H12A/SIRPA/ADCY7/ABCD1/APPL2	5
BP	GO:1900273	positive regulation of long-term synaptic potentiation	5/2306	21/18670	0.108	0.2962	0.2279	ADORA2A/SQSTM1/EIF2AK4/STAU1/NPTN	5
BP	GO:1903392	negative regulation of adherens junction organization	5/2306	21/18670	0.108	0.2962	0.2279	CORO1C/VEGFA/THBS1/RDX/PHLDB2	5
BP	GO:2000114	regulation of establishment of cell polarity	5/2306	21/18670	0.108	0.2962	0.2279	ROCK1/RUFY3/GSN/GATA3/ROCK2	5
BP	GO:2000738	positive regulation of stem cell differentiation	5/2306	21/18670	0.108	0.2962	0.2279	BMP4/SOX5/TGFB2/GATA6/TACSTD2	5
BP	GO:0007088	regulation of mitotic nuclear division	26/2306	164/18670	0.1081	0.2963	0.228	IL1B/IL1A/CHMP1B/EREG/BMP4/PDGFRB/CHMP4B/NFE2L1/EDN1/TGFA/MAD1L1/CDC14B/PPP1R9B/HECW2/CCDC8/LRP5/NSMCE2/CDKN1C/NEK6/CHMP5/PDXP/SH2B1/CDC23/IGF1/PSMG2/NPM2	26
BP	GO:0040014	regulation of multicellular organism growth	12/2306	66/18670	0.1083	0.2967	0.2283	CSF1/FTO/GHR/BBS2/GDF5/GAMT/GDF15/SH3PXD2B/ATP8A2/SOCS2/IGF1/STAT3	12
BP	GO:0010976	positive regulation of neuron projection development	42/2306	281/18670	0.1092	0.299	0.2301	NTN1/ZFYVE27/DBN1/CAPRIN1/VEGFA/EEF2K/CFLAR/PAK1/FZD1/FYN/SLIT2/BMPR2/RUFY3/KIDINS220/DPYSL3/SEMA4D/RGS2/LPAR1/ROBO1/ITPKA/ATF1/WNT5A/BHLHB9/SYT4/ARF1/PTK7/FZD4/DLG4/ATP8A2/PLXND1/TMEM106B/GDI1/SYT1/NPTN/VAMP7/ACTR2/CDH4/ITGA6/DVL1/DVL2/ANKRD27/SNX3	42
BP	GO:0022900	electron transport chain	29/2306	186/18670	0.1101	0.3014	0.2319	AKR1B1/BID/C15orf48/PPARGC1A/IDO1/COX11/CYBA/NDUFB7/DHRS3/P4HA2/SRD5A1/ADH5/CYP1A2/NDUFS4/DNAJC15/CYB5A/NDUFAB1/SDHD/ALDH5A1/PHGDH/CYB561/ME1/HSD17B6/GLRX2/POLG2/MYBBP1A/SDHAF2/CYP19A1/UQCRHL	29
BP	GO:0031100	animal organ regeneration	13/2306	73/18670	0.1104	0.3021	0.2324	CLDN1/LPIN1/CEBPB/CCND1/SULF2/NNMT/IGF2R/AXL/RGN/PGF/GAS6/PPARG/CDKN1A	13
BP	GO:0007623	circadian rhythm	32/2306	208/18670	0.1112	0.3041	0.234	NAMPT/CSF2/RELB/ID2/ADORA2A/PPARGC1A/AHR/DBP/NPAS2/ADA/SRD5A1/ARNTL/CPT1A/CSNK1E/ZFHX3/IMPDH2/SIRT1/ADORA1/ATG7/ASS1/LGR4/SERPINE1/ROCK2/PER1/PPARG/ID3/SIK1/MYCBP2/USP9X/MYBBP1A/ARNTL2/MAGEL2	32
BP	GO:0048736	appendage development	28/2306	179/18670	0.1114	0.3045	0.2343	MBNL1/PITX1/RECK/SLC7A11/BMP4/RDH10/HOXC13/NR2F2/BMPR2/HOXA11/MSX2/HOXA10/TGFB2/KAT2B/HOXD9/GDF5/GNA12/MEOX2/WNT5A/TP63/FBXW4/OSR2/RSPO2/HOXA9/FGF10/ITGA6/OSR1/TBX3	28
BP	GO:0060173	limb development	28/2306	179/18670	0.1114	0.3045	0.2343	MBNL1/PITX1/RECK/SLC7A11/BMP4/RDH10/HOXC13/NR2F2/BMPR2/HOXA11/MSX2/HOXA10/TGFB2/KAT2B/HOXD9/GDF5/GNA12/MEOX2/WNT5A/TP63/FBXW4/OSR2/RSPO2/HOXA9/FGF10/ITGA6/OSR1/TBX3	28
BP	GO:0022617	extracellular matrix disassembly	14/2306	80/18670	0.1119	0.305	0.2347	IL6/MMP1/MMP3/FSCN1/PDPN/CTSS/CD44/ETS1/MMP9/FLOT1/MMP11/SH3PXD2B/ADAM8/CAPN2	14
BP	GO:0140029	exocytic process	14/2306	80/18670	0.1119	0.305	0.2347	STX3/SNX4/SCFD2/KCNB1/SNAP47/RAB3A/SNPH/STXBP1/SYT1/VAMP7/NPPA/NAPB/PPFIA3/VPS45	14
BP	GO:0030195	negative regulation of blood coagulation	10/2306	53/18670	0.1119	0.305	0.2347	SERPINB2/C1QTNF1/PLAU/THBS1/UBASH3B/EDN1/ABAT/PRKCD/SERPINE1/SERPINF2	10
BP	GO:0045214	sarcomere organization	10/2306	53/18670	0.1119	0.305	0.2347	EDN1/MYOM1/SIX4/MEF2C/MYOM3/MIR1-2/KRT19/MYH6/ACTG1/CASQ1	10
BP	GO:0045840	positive regulation of mitotic nuclear division	10/2306	53/18670	0.1119	0.305	0.2347	IL1B/IL1A/EREG/PDGFRB/EDN1/TGFA/LRP5/NSMCE2/SH2B1/IGF1	10
BP	GO:0071320	cellular response to cAMP	10/2306	53/18670	0.1119	0.305	0.2347	AHR/AQP9/EEF2K/PKD2/SRD5A1/HCN4/ITPR2/ASS1/CPS1/SLC26A3	10
BP	GO:0001941	postsynaptic membrane organization	8/2306	40/18670	0.1128	0.3068	0.2361	SLC7A11/SSH1/LHFPL4/CHRNB1/DLG4/DVL1/CRKL/RER1	8
BP	GO:0061462	protein localization to lysosome	8/2306	40/18670	0.1128	0.3068	0.2361	GNPTAB/SH3BP4/GCC2/RTN4/KPTN/ROCK2/M6PR/NEDD4	8
BP	GO:0072210	metanephric nephron development	8/2306	40/18670	0.1128	0.3068	0.2361	LIF/STAT1/BMP4/PDGFRB/PKD2/HES5/LGR4/OSR1	8
BP	GO:0098760	response to interleukin-7	8/2306	40/18670	0.1128	0.3068	0.2361	IL7R/RAD23B/SOCS1/IRS1/HDGF/SOCS2/STAT3/CRKL	8
BP	GO:0098761	cellular response to interleukin-7	8/2306	40/18670	0.1128	0.3068	0.2361	IL7R/RAD23B/SOCS1/IRS1/HDGF/SOCS2/STAT3/CRKL	8
BP	GO:0007204	positive regulation of cytosolic calcium ion concentration	47/2306	319/18670	0.1132	0.3075	0.2366	BDKRB1/S1PR3/CXCL10/BDKRB2/FGF2/C1QTNF1/PLCE1/GSTO1/PTGFR/CMKLR1/FYN/CALM1/PDE4D/CAMK2D/PKD2/CXCL11/CCL3/CYBA/UBASH3B/OXTR/EDN1/PTGER2/CXCL9/TRPC1/F2R/CCL1/LPAR1/GNA13/ITPR2/CDK5/TPCN1/P2RX3/CALM2/MIR1-2/DLG4/FKBP1A/IAPP/DIAPH1/NPTN/ABL1/MCOLN1/NMUR2/MIR199A2/CCR10/SRI/P2RX7/CASQ1	47
BP	GO:0071156	regulation of cell cycle arrest	18/2306	108/18670	0.1138	0.3086	0.2374	ID2/PLK2/PKD2/CCND1/PRMT1/GATA6/CARM1/CDK5/BTG2/ARID3A/CNOT8/SETMAR/SLC25A33/CDKN1A/FGF10/TFDP1/MYBBP1A/FOXO4	18
BP	GO:0006417	regulation of translation	61/2306	424/18670	0.1138	0.3086	0.2374	ZC3H12A/CCL5/IL6/ACO1/HSPB1/DIO2/EIF4A2/DAPK1/CAPRIN1/PPP1R15A/ROCK1/MOV10/NGDN/RXRA/FTO/DPH5/ENC1/THBS1/ZFP36/MKNK2/EIF2AK4/ZFP36L2/PRG3/EIF4G3/RGS2/DNAJC3/ITGA2/MPV17L2/RPL22/EIF1/BCL3/SECISBP2L/MIR19B2/PABPC1/DHX29/BTG2/SAMD4B/SESN2/NSUN3/EIF3E/TNF/PUS7/MIR1-2/MIR125B1/CNOT8/EIF2B5/EIF2B4/MIR298/SYNCRIP/FASTKD3/ROCK2/FXR2/PER1/YTHDF1/ZNF706/ZNF540/MRPL13/MIR218-1/STAT3/EIF1B/ZNF598	61
BP	GO:2001242	regulation of intrinsic apoptotic signaling pathway	26/2306	165/18670	0.114	0.3086	0.2374	SOD2/BID/PTGS2/BDKRB2/HSPB1/DNAJA1/PPIF/PLEKHF1/BCL2L2/CD44/HERPUD1/BCLAF1/CYLD/PMAIP1/GRINA/NME5/SNAI2/MMP9/SIRT1/NKX3-1/BCL2L1/PRKRA/HYOU1/IVNS1ABP/MAGEA3/UBB	26
BP	GO:0032412	regulation of ion transmembrane transporter activity	39/2306	260/18670	0.1145	0.3086	0.2374	CCL2/PPARGC1A/FHL1/CNKSR3/GPD1L/DAPK1/CTSS/GSTO1/RRAD/PPIF/CALM1/PDE4D/CAMK2D/PKD2/ANK3/COX17/THADA/GRIA3/HECW2/MMP9/MEF2C/GEM/STAC/RGN/YWHAH/CALM2/ACTN4/MIR1-2/DLG4/STIM1/FKBP1A/PDE4B/NPPA/CNIH2/OSR1/SRI/CASQ1/NEDD4/ADRA2A	39
BP	GO:0033013	tetrapyrrole metabolic process	11/2306	60/18670	0.1154	0.3086	0.2374	SLC11A2/NFE2L1/CYP1A2/ABCC1/MTR/HMOX2/ALAS1/SLC25A39/BDH2/SUCLA2/MMADHC	11
BP	GO:0043966	histone H3 acetylation	11/2306	60/18670	0.1154	0.3086	0.2374	LIF/BRPF3/DR1/KAT2B/YEATS2/SIRT1/GATA3/TAF6L/PER1/ZNF451/TADA3	11
BP	GO:0120193	tight junction organization	11/2306	60/18670	0.1154	0.3086	0.2374	CLDN1/ROCK1/RAB13/SNAI2/TNF/ACTN4/ROCK2/TJP1/PDCD6IP/NPHP1/CBFB	11
BP	GO:1901343	negative regulation of vasculature development	29/2306	187/18670	0.1157	0.3086	0.2374	CXCL10/THBS2/STAT1/ROCK1/PLK2/BMP4/KLF2/KLF4/HSPG2/THBS1/E2F2/CARD10/TGFB2/STARD13/MEOX2/MIR19B2/SULF1/FOXJ2/MIR137/SPARC/MIR125B1/PTPRM/HLA-G/SERPINE1/ROCK2/MIR214/PDE3B/PPARG/FOXO4	29
BP	GO:0006171	cAMP biosynthetic process	3/2306	10/18670	0.1162	0.3086	0.2374	ADCY7/ADCY9/ADCY3	3
BP	GO:0006569	tryptophan catabolic process	3/2306	10/18670	0.1162	0.3086	0.2374	KYNU/IDO1/AADAT	3
BP	GO:0006930	substrate-dependent cell migration, cell extension	3/2306	10/18670	0.1162	0.3086	0.2374	NTN1/SDCBP/MYH10	3
BP	GO:0009157	deoxyribonucleoside monophosphate biosynthetic process	3/2306	10/18670	0.1162	0.3086	0.2374	CDADC1/TK2/DCK	3
BP	GO:0010615	positive regulation of cardiac muscle adaptation	3/2306	10/18670	0.1162	0.3086	0.2374	PPP3CA/MIR214/MIR199A2	3
BP	GO:0010739	positive regulation of protein kinase A signaling	3/2306	10/18670	0.1162	0.3086	0.2374	AKAP12/MC1R/IAPP	3
BP	GO:0016559	peroxisome fission	3/2306	10/18670	0.1162	0.3086	0.2374	PEX11G/PEX11B/ACOT8	3
BP	GO:0032000	positive regulation of fatty acid beta-oxidation	3/2306	10/18670	0.1162	0.3086	0.2374	IRS1/CPT1A/ABCD1	3
BP	GO:0032308	positive regulation of prostaglandin secretion	3/2306	10/18670	0.1162	0.3086	0.2374	IL1B/EDN1/P2RX7	3
BP	GO:0032353	negative regulation of hormone biosynthetic process	3/2306	10/18670	0.1162	0.3086	0.2374	BMP2/NFKB1/CYP27B1	3
BP	GO:0032836	glomerular basement membrane development	3/2306	10/18670	0.1162	0.3086	0.2374	SULF2/MYO1E/SULF1	3
BP	GO:0034135	regulation of toll-like receptor 2 signaling pathway	3/2306	10/18670	0.1162	0.3086	0.2374	TNFAIP3/CYBA/PJA2	3
BP	GO:0035090	maintenance of apical/basal cell polarity	3/2306	10/18670	0.1162	0.3086	0.2374	LIN7A/LIN7C/PDCD6IP	3
BP	GO:0035247	peptidyl-arginine omega-N-methylation	3/2306	10/18670	0.1162	0.3086	0.2374	PRMT1/CARM1/PRMT3	3
BP	GO:0035646	endosome to melanosome transport	3/2306	10/18670	0.1162	0.3086	0.2374	RAB38/RAB32/ANKRD27	3
BP	GO:0035672	oligopeptide transmembrane transport	3/2306	10/18670	0.1162	0.3086	0.2374	SLC15A3/SLC7A11/ABCC1	3
BP	GO:0035878	nail development	3/2306	10/18670	0.1162	0.3086	0.2374	HOXC13/MSX2/ITGA6	3
BP	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway	3/2306	10/18670	0.1162	0.3086	0.2374	COL1A1/UBASH3B/COL4A1	3
BP	GO:0042436	indole-containing compound catabolic process	3/2306	10/18670	0.1162	0.3086	0.2374	KYNU/IDO1/AADAT	3
BP	GO:0043485	endosome to pigment granule transport	3/2306	10/18670	0.1162	0.3086	0.2374	RAB38/RAB32/ANKRD27	3
BP	GO:0044359	modulation of molecular function in other organism	3/2306	10/18670	0.1162	0.3086	0.2374	RAB9A/PTX3/NUCKS1	3
BP	GO:0045199	maintenance of epithelial cell apical/basal polarity	3/2306	10/18670	0.1162	0.3086	0.2374	LIN7A/LIN7C/PDCD6IP	3
BP	GO:0045988	negative regulation of striated muscle contraction	3/2306	10/18670	0.1162	0.3086	0.2374	ZC3H12A/PDE5A/SRI	3
BP	GO:0046218	indolalkylamine catabolic process	3/2306	10/18670	0.1162	0.3086	0.2374	KYNU/IDO1/AADAT	3
BP	GO:0048757	pigment granule maturation	3/2306	10/18670	0.1162	0.3086	0.2374	RAB38/RAB32/ANKRD27	3
BP	GO:0051409	response to nitrosative stress	3/2306	10/18670	0.1162	0.3086	0.2374	DUSP6/DNAJA1/ADH5	3
BP	GO:0051918	negative regulation of fibrinolysis	3/2306	10/18670	0.1162	0.3086	0.2374	THBS1/SERPINE1/SERPINF2	3
BP	GO:0052205	modulation of molecular function in other organism involved in symbiotic interaction	3/2306	10/18670	0.1162	0.3086	0.2374	RAB9A/PTX3/NUCKS1	3
BP	GO:0052646	alditol phosphate metabolic process	3/2306	10/18670	0.1162	0.3086	0.2374	GK/GPD1L/GPAM	3
BP	GO:0060281	regulation of oocyte development	3/2306	10/18670	0.1162	0.3086	0.2374	NPR2/PDE5A/IGF1	3
BP	GO:0061140	lung secretory cell differentiation	3/2306	10/18670	0.1162	0.3086	0.2374	GATA6/FGF10/NFIB	3
BP	GO:0072015	glomerular visceral epithelial cell development	3/2306	10/18670	0.1162	0.3086	0.2374	BMP4/MYO1E/PODXL	3
BP	GO:0072124	regulation of glomerular mesangial cell proliferation	3/2306	10/18670	0.1162	0.3086	0.2374	CFLAR/BMP4/PDGFD	3
BP	GO:0072203	cell proliferation involved in metanephros development	3/2306	10/18670	0.1162	0.3086	0.2374	STAT1/PDGFRB/OSR1	3
BP	GO:0090154	positive regulation of sphingolipid biosynthetic process	3/2306	10/18670	0.1162	0.3086	0.2374	TNF/PRKCD/NSMAF	3
BP	GO:0090557	establishment of endothelial intestinal barrier	3/2306	10/18670	0.1162	0.3086	0.2374	ICAM1/CLDN1/TJP1	3
BP	GO:0097050	type B pancreatic cell apoptotic process	3/2306	10/18670	0.1162	0.3086	0.2374	IL6/TCF7L2/CAST	3
BP	GO:0098917	retrograde trans-synaptic signaling	3/2306	10/18670	0.1162	0.3086	0.2374	DAGLA/SYT4/DAGLB	3
BP	GO:0110096	cellular response to aldehyde	3/2306	10/18670	0.1162	0.3086	0.2374	AKR1B1/ADH5/ESD	3
BP	GO:1903244	positive regulation of cardiac muscle hypertrophy in response to stress	3/2306	10/18670	0.1162	0.3086	0.2374	PPP3CA/MIR214/MIR199A2	3
BP	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA	3/2306	10/18670	0.1162	0.3086	0.2374	ZC3H12A/PPP3CA/NCOR2	3
BP	GO:1905879	regulation of oogenesis	3/2306	10/18670	0.1162	0.3086	0.2374	NPR2/PDE5A/IGF1	3
BP	GO:1990535	neuron projection maintenance	3/2306	10/18670	0.1162	0.3086	0.2374	DCTN1/MAP1A/ABCD1	3
BP	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin	3/2306	10/18670	0.1162	0.3086	0.2374	FLOT1/WNT5A/SERPINF2	3
BP	GO:2000304	positive regulation of ceramide biosynthetic process	3/2306	10/18670	0.1162	0.3086	0.2374	TNF/PRKCD/NSMAF	3
BP	GO:0016999	antibiotic metabolic process	24/2306	151/18670	0.1163	0.3088	0.2376	AKR1B1/CYP4B1/ST3GAL1/ACO1/MMP3/FYN/NAGK/IDH1/CYBA/ADH5/CYP1A2/CBR4/FH/SULT1C4/ABCC2/ESD/PDHB/SDHD/ALDH5A1/HBB/SUCLA2/ADH1C/STAT3/SDHAF2	24
BP	GO:0022898	regulation of transmembrane transporter activity	40/2306	268/18670	0.1174	0.3114	0.2396	CCL2/PPARGC1A/FHL1/CNKSR3/GPD1L/DAPK1/CTSS/GSTO1/RRAD/PPIF/CALM1/PDE4D/CAMK2D/PKD2/ANK3/COX17/THADA/GRIA3/HECW2/MMP9/MEF2C/GEM/STAC/RGN/ACTB/YWHAH/CALM2/ACTN4/MIR1-2/DLG4/STIM1/FKBP1A/PDE4B/NPPA/CNIH2/OSR1/SRI/CASQ1/NEDD4/ADRA2A	40
BP	GO:0032387	negative regulation of intracellular transport	12/2306	67/18670	0.1179	0.3124	0.2404	RAB23/CRYAB/CDK5/ARHGAP1/SYT4/TXN/SP100/GDI1/PKIG/FERMT1/CNIH2/SNX3	12
BP	GO:0051298	centrosome duplication	12/2306	67/18670	0.1179	0.3124	0.2404	RTTN/CHMP1B/ARHGEF10/PLK2/CHMP4B/PKD2/TRIM37/KAT2B/CHMP5/ROCK2/CEP63/PDCD6IP	12
BP	GO:0060038	cardiac muscle cell proliferation	12/2306	67/18670	0.1179	0.3124	0.2404	FGF2/MEIS1/JARID2/RXRA/PIM1/TGFB2/GATA6/YAP1/MEF2C/MIR19B2/MIR1-2/MIR199A2	12
BP	GO:0010639	negative regulation of organelle organization	57/2306	395/18670	0.1179	0.3124	0.2404	LIF/PPARGC1A/JARID2/BMP4/MID1/PPFIA1/LIMA1/SET/PPIF/SLIT2/CHMP4B/MYADM/LMNA/TRIM37/TBC1D4/FNIP2/ARHGAP28/TET1/UBR5/RDX/FNIP1/MAD1L1/KAT2B/PLEKHH2/TCHP/POT1/CLIP3/PHLDB2/SIRT1/EVI5L/ATG7/CAPZA2/BCL2L1/SYT4/PFN2/ACAA2/EPS8/GSN/TACSTD2/IAPP/PRKCD/TMEM14A/GMFB/SETMAR/MIR214/ASF1A/TMOD2/MNAT1/FEZ2/IGF1/PSMG2/TAOK1/ZNF451/ANKRD27/MID1IP1/CAMSAP1/WASF2	57
BP	GO:0006099	tricarboxylic acid cycle	7/2306	34/18670	0.1183	0.3126	0.2405	ACO1/IDH1/FH/PDHB/SDHD/SUCLA2/SDHAF2	7
BP	GO:0009164	nucleoside catabolic process	7/2306	34/18670	0.1183	0.3126	0.2405	TYMP/APOBEC3G/NUDT18/ADA/APOBEC3H/CDADC1/APOBEC3F	7
BP	GO:0016601	Rac protein signal transduction	7/2306	34/18670	0.1183	0.3126	0.2405	AUTS2/STMN3/NISCH/RHOU/ARF6/EPS8/WASF2	7
BP	GO:0032148	activation of protein kinase B activity	7/2306	34/18670	0.1183	0.3126	0.2405	CCDC88A/WNT5A/TXN/GAS6/IGF1/ADRA2A/PRR5	7
BP	GO:0042558	pteridine-containing compound metabolic process	7/2306	34/18670	0.1183	0.3126	0.2405	MTHFD2L/GCH1/MTHFD2/MTR/SLC19A1/ALDH1L2/PTS	7
BP	GO:0071875	adrenergic receptor signaling pathway	7/2306	34/18670	0.1183	0.3126	0.2405	PDE4D/RGS2/ADCY9/ARRDC3/MIR1-2/ADRB3/ADRA2A	7
BP	GO:0002832	negative regulation of response to biotic stimulus	9/2306	47/18670	0.1188	0.313	0.2409	TNFAIP3/TRIB1/TSPAN6/ITCH/DHX58/MICB/HAVCR2/TRIM38/MAPKBP1	9
BP	GO:0046638	positive regulation of alpha-beta T cell differentiation	9/2306	47/18670	0.1188	0.313	0.2409	NFKBIZ/CD83/RIPK2/MYB/IL4R/SOCS1/ADA/SASH3/CBFB	9
BP	GO:0060986	endocrine hormone secretion	9/2306	47/18670	0.1188	0.313	0.2409	IL1B/C1QTNF1/INHBB/NKX3-1/FZD4/GATA3/RAB11FIP1/PTPN11/TBX3	9
BP	GO:0070169	positive regulation of biomineral tissue development	9/2306	47/18670	0.1188	0.313	0.2409	BMP2/CEBPB/ISG15/BMP4/BMPR2/MEF2C/OSR2/OSR1/P2RX7	9
BP	GO:0070231	T cell apoptotic process	9/2306	47/18670	0.1188	0.313	0.2409	CCL5/IL7R/IDO1/BMP4/FADD/ADA/WNT5A/BCL10/ADAM8	9
BP	GO:1903115	regulation of actin filament-based movement	9/2306	47/18670	0.1188	0.313	0.2409	PDPN/PDE4D/CAMK2D/HCN4/ADORA1/ATP2A2/MIR1-2/PDE4B/SRI	9
BP	GO:0006997	nucleus organization	21/2306	130/18670	0.1194	0.3144	0.2419	CHMP1B/LPIN1/PRKCA/ETS1/NUP133/CHMP4B/NFE2L1/LMNA/DMPK/HIPK2/DCTN1/TNP2/SERBP1/NEK6/PARP11/ANKLE2/CHMP5/RTN4/TOR1A/PSME4/NUP35	21
BP	GO:0006081	cellular aldehyde metabolic process	13/2306	74/18670	0.1196	0.3148	0.2422	BMP2/ALDH1A3/CYP27C1/RDH10/PNKD/IDH1/PNPO/ADH5/HAGH/ALDH7A1/ESD/PDXP/RDH13	13
BP	GO:0009064	glutamine family amino acid metabolic process	13/2306	74/18670	0.1196	0.3148	0.2422	GFPT2/DDAH1/GLS/SLC7A11/FAH/GLUD1/AADAT/ASS1/ASNS/DDAH2/ALDH5A1/PHGDH/CPS1	13
BP	GO:0030104	water homeostasis	13/2306	74/18670	0.1196	0.3148	0.2422	AKR1B1/CLDN1/AQP9/UGCG/KRT16/ADCY7/RAB11FIP2/ADCY9/HAS2/ADCY3/TP63/SCNN1A/FLG	13
BP	GO:0006913	nucleocytoplasmic transport	50/2306	343/18670	0.12	0.3155	0.2428	NFKBIA/ZC3H12A/PTGS2/IL1B/RAB23/MX2/YTHDC1/LZTS2/BMP4/PPP1R12A/NUP133/LMNA/DDX20/PIK3R2/UBR5/TCF7L2/CPSF2/ARNTL/NXF1/KPNA3/CPSF6/CDK5/RPAIN/TXN/RANBP3L/APPL2/SP100/DUSP16/PRKCD/IWS1/PPP3CA/CTDSPL2/NXT1/GAS6/PKIG/HTATIP2/CDKN1A/PTPN11/KPNA2/RANBP17/NUP35/ANP32C/FERMT1/CBLB/STAT3/NEDD4/NUP62CL/CHP2/XPO7/DDX19A	50
BP	GO:0016125	sterol metabolic process	26/2306	166/18670	0.12	0.3155	0.2428	CH25H/ABCA1/INSIG2/OSBPL1A/ACACB/LIPA/LIMA1/RXRA/NFE2L1/SCD/CYB5R2/TM7SF2/ACAT2/ACACA/NPC1L1/SOAT1/ACAA2/OSBPL5/HSD3B7/CLN8/HSD17B7/CEBPA/GPAM/IDI1/CYP19A1/SULT2B1	26
BP	GO:0060761	negative regulation of response to cytokine stimulus	14/2306	81/18670	0.1208	0.3173	0.2441	CCL5/IL6/PARP14/IRAK3/SLIT2/KLF4/ADAR/ROBO1/MIR125B1/GAS6/PPARG/PYDC2/ZNF675/PELI3	14
BP	GO:1900180	regulation of protein localization to nucleus	19/2306	116/18670	0.1208	0.3174	0.2442	ZC3H12A/PTGS2/LIF/RAB23/LZTS2/BMP4/FYN/LMNA/TRIM29/PIK3R2/UBR5/CARD10/PARP9/SESN2/PRKCD/PKIG/FERMT1/DCLK2/CHP2	19
BP	GO:0042147	retrograde transport, endosome to Golgi	15/2306	88/18670	0.1214	0.3181	0.2448	DENND5A/RAB9A/STX6/GCC2/CLTC/DCTN1/RHOBTB3/VPS35/PREPL/RAB9B/STX16/TBC1D10C/RNF126/VPS26A/MAGEL2	15
BP	GO:1903321	negative regulation of protein modification by small protein conjugation or removal	15/2306	88/18670	0.1214	0.3181	0.2448	TNFAIP3/BAG2/ISG15/PRR7/DNAJA1/FYN/UBR5/CDK5/TRIM21/UBXN1/PRMT3/IVNS1ABP/ABL1/SH3RF2/PIAS3	15
BP	GO:0031345	negative regulation of cell projection organization	29/2306	188/18670	0.1214	0.3181	0.2448	NTN1/DENND5A/PLK2/FYN/SLIT2/RUFY3/DPYSL3/SEMA4D/LPAR1/TCHP/CARM1/IFRD1/CDK5/WNT5A/EVI5L/ARF6/PFN2/YWHAH/TACSTD2/GDI1/ASAP1/PRKCD/CRMP1/RTN4/PPP3CA/MIR214/SEMA4F/MYLIP/NGEF	29
BP	GO:0043902	positive regulation of multi-organism process	29/2306	188/18670	0.1214	0.3181	0.2448	CCL5/RIPK2/PRKCA/DDX60/IFIT1/CHMP4B/ADAR/CYBA/OXTR/DHX58/INHBB/LHFPL2/PPIA/PDE12/IGF2R/OPTN/PABPC1/TRIM21/RAD23A/HAVCR2/STAU1/ADARB1/ZNF639/NUCKS1/KPNA2/PKN2/PDE5A/TRIM38/GTF2F2	29
BP	GO:0051783	regulation of nuclear division	29/2306	188/18670	0.1214	0.3181	0.2448	IL1B/LIF/IL1A/CHMP1B/EREG/BMP4/PDGFRB/CHMP4B/NFE2L1/MSX2/EDN1/TGFA/MAD1L1/CDC14B/PPP1R9B/HECW2/CCDC8/LRP5/NSMCE2/WNT5A/CDKN1C/NEK6/CHMP5/PDXP/SH2B1/CDC23/IGF1/PSMG2/NPM2	29
BP	GO:0098727	maintenance of cell number	25/2306	159/18670	0.1214	0.3181	0.2448	LIF/KIT/FGF2/FOXO1/LDB2/MED10/KLF4/TET1/LBH/ZFP36L2/YAP1/ASCL2/GNL3/TP63/HES5/HOOK3/ARID1A/MMP24/EPHA1/FGF10/ZNF706/IGF1/STAT3/FZD7/TBX3	25
BP	GO:0015837	amine transport	17/2306	102/18670	0.1216	0.3184	0.2449	ADORA2A/AQP9/ARL6IP5/OXTR/RAB3GAP1/RGS2/RGS4/ADORA1/KCNB1/SYT4/ABAT/STXBP1/SYT1/TOR1A/OSR1/P2RX7/ADRA2A	17
BP	GO:0030148	sphingolipid biosynthetic process	17/2306	102/18670	0.1216	0.3184	0.2449	ST8SIA1/ELOVL5/B4GALT3/UGCG/ELOVL7/A4GALT/CSNK1G2/ELOVL2/UGT8/TNF/CLN8/PRKCD/SGMS2/NSMAF/P2RX7/SAMD8/ELOVL3	17
BP	GO:0051952	regulation of amine transport	16/2306	95/18670	0.1217	0.3184	0.2449	ADORA2A/ARL6IP5/OXTR/RAB3GAP1/RGS2/RGS4/ADORA1/KCNB1/SYT4/ABAT/STXBP1/SYT1/TOR1A/OSR1/P2RX7/ADRA2A	16
BP	GO:0016202	regulation of striated muscle tissue development	24/2306	152/18670	0.1228	0.32	0.2462	BMP2/FGF2/MEIS1/JARID2/SIX1/BMP4/PAK1/PIM1/EDN1/ARNTL/RGS2/GATA6/YAP1/FLOT1/SIX4/MEF2C/AKIRIN1/MIR19B2/RGS4/DDX5/MIR1-2/MIR199A2/IGF1/FZD7	24
BP	GO:0030042	actin filament depolymerization	10/2306	54/18670	0.123	0.32	0.2462	LIMA1/RDX/DSTN/PLEKHH2/CAPZA2/MICAL3/EPS8/GSN/PDXP/TMOD2	10
BP	GO:0030199	collagen fibril organization	10/2306	54/18670	0.123	0.32	0.2462	COL1A1/LOXL4/COL5A2/TGFB2/PLOD2/MMP11/SERPINH1/COL1A2/SERPINF2/COL5A1	10
BP	GO:0032655	regulation of interleukin-12 production	10/2306	54/18670	0.123	0.32	0.2462	RIPK2/NFKB1/IRF1/IDO1/CMKLR1/CD40/IRAK3/THBS1/TLR3/HLA-G	10
BP	GO:0070206	protein trimerization	10/2306	54/18670	0.123	0.32	0.2462	C1QTNF1/COL1A1/TRAF2/TRIM21/P2RX3/MLKL/TRIM6/HLA-G/COL1A2/SIGMAR1	10
BP	GO:1900047	negative regulation of hemostasis	10/2306	54/18670	0.123	0.32	0.2462	SERPINB2/C1QTNF1/PLAU/THBS1/UBASH3B/EDN1/ABAT/PRKCD/SERPINE1/SERPINF2	10
BP	GO:0001516	prostaglandin biosynthetic process	6/2306	28/18670	0.1231	0.32	0.2462	PTGS2/IL1B/PTGES/EDN1/SIRT1/PTGS1	6
BP	GO:0009074	aromatic amino acid family catabolic process	6/2306	28/18670	0.1231	0.32	0.2462	KYNU/IDO1/IL4I1/FAH/HNMT/AADAT	6
BP	GO:0032196	transposition	6/2306	28/18670	0.1231	0.32	0.2462	APOBEC3G/MOV10/MYBL1/APOBEC3H/ZNF91/APOBEC3F	6
BP	GO:0043501	skeletal muscle adaptation	6/2306	28/18670	0.1231	0.32	0.2462	PPARGC1A/CFLAR/IL15/CAMK2G/ATP2A2/PPP3CA	6
BP	GO:0046457	prostanoid biosynthetic process	6/2306	28/18670	0.1231	0.32	0.2462	PTGS2/IL1B/PTGES/EDN1/SIRT1/PTGS1	6
BP	GO:0090383	phagosome acidification	6/2306	28/18670	0.1231	0.32	0.2462	ATP6V1E2/ATP6V0B/RAB38/ATP6V0E2/SLAMF8/ATP6V1E1	6
BP	GO:0006941	striated muscle contraction	27/2306	174/18670	0.1247	0.32	0.2462	ZC3H12A/GPD1L/GSTO1/CALM1/PDE4D/CAMK2D/ACTC1/DMPK/SGCD/RGS2/SYNM/HCN4/STAC/ADORA1/CALM2/CHRNB1/ATP2A2/MIR1-2/ATP8A2/SNTA1/PDE4B/KCND3/MYH6/NPPA/PDE5A/SRI/CASQ1	27
BP	GO:0090287	regulation of cellular response to growth factor stimulus	43/2306	292/18670	0.1256	0.32	0.2462	IL1B/CITED2/DAB2/FGF2/MYOF/VEGFA/CFLAR/BMP4/GREM2/FZD1/SLIT2/BMPR2/DOK5/THBS1/MSX2/SULF2/BMPER/SDCBP/HIPK2/SPRY1/GDF5/ROBO1/SIRT1/WNT5A/SULF1/HES5/CDKN1C/SHISA2/FBN1/MIR1-2/FZD4/GATA3/FST/NPTN/ABL1/CTDSPL2/UBB/ENG/FGF10/FERMT1/TMEM108/ZNF451/NEDD4	43
BP	GO:0001977	renal system process involved in regulation of blood volume	4/2306	16/18670	0.1258	0.32	0.2462	CYBA/F2R/ADORA1/GAS6	4
BP	GO:0002643	regulation of tolerance induction	4/2306	16/18670	0.1258	0.32	0.2462	IDO1/IRAK3/HAVCR2/HLA-G	4
BP	GO:0006047	UDP-N-acetylglucosamine metabolic process	4/2306	16/18670	0.1258	0.32	0.2462	GFPT2/NAGK/PGM3/MGAT1	4
BP	GO:0014061	regulation of norepinephrine secretion	4/2306	16/18670	0.1258	0.32	0.2462	ADORA2A/OXTR/KCNB1/ADRA2A	4
BP	GO:0014866	skeletal myofibril assembly	4/2306	16/18670	0.1258	0.32	0.2462	CFLAR/ACTC1/MYOM1/MYOM3	4
BP	GO:0030397	membrane disassembly	4/2306	16/18670	0.1258	0.32	0.2462	LPIN1/PRKCA/DCTN1/NEK6	4
BP	GO:0031269	pseudopodium assembly	4/2306	16/18670	0.1258	0.32	0.2462	KIT/CDC42EP1/CDC42EP3/CDC42	4
BP	GO:0032225	regulation of synaptic transmission, dopaminergic	4/2306	16/18670	0.1258	0.32	0.2462	PTGS2/PNKD/FLOT1/TOR1A	4
BP	GO:0032354	response to follicle-stimulating hormone	4/2306	16/18670	0.1258	0.32	0.2462	PPARGC1A/SRD5A1/ASNS/PAPPA	4
BP	GO:0032695	negative regulation of interleukin-12 production	4/2306	16/18670	0.1258	0.32	0.2462	NFKB1/CMKLR1/IRAK3/THBS1	4
BP	GO:0033631	cell-cell adhesion mediated by integrin	4/2306	16/18670	0.1258	0.32	0.2462	CCL5/ITGA4/ADA/PODXL	4
BP	GO:0034116	positive regulation of heterotypic cell-cell adhesion	4/2306	16/18670	0.1258	0.32	0.2462	IL1B/CD44/FLOT1/TNF	4
BP	GO:0035970	peptidyl-threonine dephosphorylation	4/2306	16/18670	0.1258	0.32	0.2462	PPM1D/DUSP18/DUSP10/DUSP5	4
BP	GO:0044065	regulation of respiratory system process	4/2306	16/18670	0.1258	0.32	0.2462	GLS/FTO/ADORA1/TSHZ3	4
BP	GO:0045722	positive regulation of gluconeogenesis	4/2306	16/18670	0.1258	0.32	0.2462	PPARGC1A/FOXO1/KAT2B/SIRT1	4
BP	GO:0045986	negative regulation of smooth muscle contraction	4/2306	16/18670	0.1258	0.32	0.2462	PTGS2/RGS2/ADORA1/DOCK4	4
BP	GO:0045989	positive regulation of striated muscle contraction	4/2306	16/18670	0.1258	0.32	0.2462	GSTO1/RGS2/MIR1-2/NPPA	4
BP	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter	4/2306	16/18670	0.1258	0.32	0.2462	RAB3GAP1/SYT4/ATP2A2/SYT1	4
BP	GO:0051081	nuclear envelope disassembly	4/2306	16/18670	0.1258	0.32	0.2462	LPIN1/PRKCA/DCTN1/NEK6	4
BP	GO:0051238	sequestering of metal ion	4/2306	16/18670	0.1258	0.32	0.2462	FTH1/SLC30A7/FTHL17/SRI	4
BP	GO:0055012	ventricular cardiac muscle cell differentiation	4/2306	16/18670	0.1258	0.32	0.2462	RXRA/LMNA/MEF2C/MYH10	4
BP	GO:0060965	negative regulation of gene silencing by miRNA	4/2306	16/18670	0.1258	0.32	0.2462	ZC3H12A/PPP3CA/NCOR2/PPARG	4
BP	GO:0061158	3'-UTR-mediated mRNA destabilization	4/2306	16/18670	0.1258	0.32	0.2462	ZC3H12A/MOV10/ZFP36/ZFP36L2	4
BP	GO:0061548	ganglion development	4/2306	16/18670	0.1258	0.32	0.2462	TUBB3/SIX1/SIX4/RGS4	4
BP	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade	4/2306	16/18670	0.1258	0.32	0.2462	LMCD1/TNF/IGF1/CHP2	4
BP	GO:0071871	response to epinephrine	4/2306	16/18670	0.1258	0.32	0.2462	PPARGC1A/PDE4D/SRD5A1/PDE4B	4
BP	GO:0072109	glomerular mesangium development	4/2306	16/18670	0.1258	0.32	0.2462	CFLAR/BMP4/PDGFRB/PDGFD	4
BP	GO:0090153	regulation of sphingolipid biosynthetic process	4/2306	16/18670	0.1258	0.32	0.2462	TNF/PRKCD/NSMAF/SAMD8	4
BP	GO:0090493	catecholamine uptake	4/2306	16/18670	0.1258	0.32	0.2462	SLC22A1/ACTB/SLC22A3/TOR1A	4
BP	GO:0106058	positive regulation of calcineurin-mediated signaling	4/2306	16/18670	0.1258	0.32	0.2462	LMCD1/TNF/IGF1/CHP2	4
BP	GO:1900242	regulation of synaptic vesicle endocytosis	4/2306	16/18670	0.1258	0.32	0.2462	PPP3CC/ROCK1/VAMP4/TOR1A	4
BP	GO:1902004	positive regulation of amyloid-beta formation	4/2306	16/18670	0.1258	0.32	0.2462	IFNGR1/TNF/ROCK2/PICALM	4
BP	GO:1903541	regulation of exosomal secretion	4/2306	16/18670	0.1258	0.32	0.2462	SDCBP/SDC4/ATP13A2/PDCD6IP	4
BP	GO:1905038	regulation of membrane lipid metabolic process	4/2306	16/18670	0.1258	0.32	0.2462	TNF/PRKCD/NSMAF/SAMD8	4
BP	GO:1990000	amyloid fibril formation	4/2306	16/18670	0.1258	0.32	0.2462	CRYAB/GSN/FKBP1A/IAPP	4
BP	GO:2000303	regulation of ceramide biosynthetic process	4/2306	16/18670	0.1258	0.32	0.2462	TNF/PRKCD/NSMAF/SAMD8	4
BP	GO:2001170	negative regulation of ATP biosynthetic process	4/2306	16/18670	0.1258	0.32	0.2462	PID1/PPARGC1A/STAT3/SIRT6	4
BP	GO:0040019	positive regulation of embryonic development	8/2306	41/18670	0.1259	0.32	0.2462	SIX1/PHLDB1/SIX4/PHLDB2/MIR1-2/GATA3/IGF1/OSR1	8
BP	GO:0048286	lung alveolus development	8/2306	41/18670	0.1259	0.32	0.2462	LIF/SLC7A11/BMP4/BMPR2/ADA/GATA6/ERRFI1/FGF10	8
BP	GO:0050798	activated T cell proliferation	8/2306	41/18670	0.1259	0.32	0.2462	TNFSF9/PDCD1LG2/BTN3A1/FYN/LRRC32/FADD/ABL1/IGF1	8
BP	GO:0098927	vesicle-mediated transport between endosomal compartments	8/2306	41/18670	0.1259	0.32	0.2462	DAB2/RDX/HOOK3/WDR91/AKTIP/MYO1D/ANKRD27/SNX3	8
BP	GO:0034113	heterotypic cell-cell adhesion	11/2306	61/18670	0.126	0.32	0.2462	VCAM1/IL1B/CD44/CD58/MYADM/KLF4/ITGA4/MBP/SIRPA/FLOT1/TNF	11
BP	GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	11/2306	61/18670	0.126	0.32	0.2462	NFKBIZ/ZC3H12A/CD83/RIPK2/SH3RF1/MYB/IL4R/SOCS1/GATA3/SASH3/CBFB	11
BP	GO:0009914	hormone transport	47/2306	322/18670	0.1263	0.32	0.2462	CCL5/IL6/IL1B/LIF/ENSA/ADORA2A/C1QTNF1/PRKCA/SLC2A1/SLC22A1/GIP/MYB/IRS1/SNX4/GLUD1/EDN1/HADH/SLCO4A1/TCF7L2/INHBB/ARNTL/CPT1A/RAB11FIP2/LRP5/ITPR2/ABCC2/ADORA1/KCNB1/NKX3-1/ABAT/TNF/CAMK2G/SYTL4/DYNLL1/BRSK2/FZD4/GATA3/PPP3CA/RAB11FIP1/VAMP7/PTPN11/NPPA/ARL2BP/SRI/CYP19A1/ADRA2A/TBX3	47
BP	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	5/2306	22/18670	0.1263	0.32	0.2462	RCL1/UTP20/BOP1/URB1/FTSJ3	5
BP	GO:0000717	nucleotide-excision repair, DNA duplex unwinding	5/2306	22/18670	0.1263	0.32	0.2462	RAD23B/ERCC2/DDB2/GTF2H5/UBB	5
BP	GO:0002089	lens morphogenesis in camera-type eye	5/2306	22/18670	0.1263	0.32	0.2462	MEIS1/BMP4/BCAR3/HIPK2/SHROOM2	5
BP	GO:0005980	glycogen catabolic process	5/2306	22/18670	0.1263	0.32	0.2462	PYGL/CALM1/PGM2L1/PHKB/PHKA2	5
BP	GO:0006379	mRNA cleavage	5/2306	22/18670	0.1263	0.32	0.2462	ERN1/MOV10/CPSF2/CPSF6/RNASE4	5
BP	GO:0009190	cyclic nucleotide biosynthetic process	5/2306	22/18670	0.1263	0.32	0.2462	ADCY7/ADCY9/ADCY3/NPR2/NPPA	5
BP	GO:0010884	positive regulation of lipid storage	5/2306	22/18670	0.1263	0.32	0.2462	ZC3H12A/NFKB1/C3/ACACB/EHD1	5
BP	GO:0031342	negative regulation of cell killing	5/2306	22/18670	0.1263	0.32	0.2462	IL7R/HLA-E/HLA-F/HAVCR2/HLA-G	5
BP	GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane	5/2306	22/18670	0.1263	0.32	0.2462	STX3/SNAP47/RAB3A/STXBP1/SYT1	5
BP	GO:0032469	endoplasmic reticulum calcium ion homeostasis	5/2306	22/18670	0.1263	0.32	0.2462	HERPUD1/CAMK2D/THADA/GRINA/ATP2A2	5
BP	GO:0035809	regulation of urine volume	5/2306	22/18670	0.1263	0.32	0.2462	AKR1B1/ADORA2A/NPR3/EDN1/HAS2	5
BP	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	5/2306	22/18670	0.1263	0.32	0.2462	VPS37D/VPS36/VPS37C/RNF126/NEDD4	5
BP	GO:0046628	positive regulation of insulin receptor signaling pathway	5/2306	22/18670	0.1263	0.32	0.2462	PAK1/IRS1/SIRT1/NUCKS1/PTPN11	5
BP	GO:0051195	negative regulation of cofactor metabolic process	5/2306	22/18670	0.1263	0.32	0.2462	MMP3/PPARGC1A/FYN/STAT3/SIRT6	5
BP	GO:0052652	cyclic purine nucleotide metabolic process	5/2306	22/18670	0.1263	0.32	0.2462	ADCY7/ADCY9/ADCY3/NPR2/NPPA	5
BP	GO:0060575	intestinal epithelial cell differentiation	5/2306	22/18670	0.1263	0.32	0.2462	YIPF6/GATA6/C1GALT1/PRDM1/CDKN1A	5
BP	GO:0072643	interferon-gamma secretion	5/2306	22/18670	0.1263	0.32	0.2462	ZC3H12A/ISG15/BTN3A1/GATA3/ABL1	5
BP	GO:0097320	plasma membrane tubulation	5/2306	22/18670	0.1263	0.32	0.2462	FNBP1L/SGIP1/MICALL1/BIN3/ASAP1	5
BP	GO:0140112	extracellular vesicle biogenesis	5/2306	22/18670	0.1263	0.32	0.2462	SDCBP/ARRDC4/SDC4/ATP13A2/PDCD6IP	5
BP	GO:2000773	negative regulation of cellular senescence	5/2306	22/18670	0.1263	0.32	0.2462	NAMPT/CDK6/PLK2/SIRT1/ABL1	5
BP	GO:0015980	energy derivation by oxidation of organic compounds	42/2306	285/18670	0.1277	0.3234	0.2488	BID/GFPT2/PID1/ACO1/PPARGC1A/PYGL/IL6ST/PPP1R3F/UGP2/CALM1/COQ10B/IRS1/IDH1/PGM2L1/NDUFB7/FASTKD5/DYRK2/MTFR1/PHLDA2/ENPP1/PHKB/CYP1A2/FH/NDUFS4/DNAJC15/NDUFAB1/MRAP2/PDHB/SDHD/GYG1/ALDH5A1/ADRB3/GYS2/FASTKD3/SUCLA2/PHKA2/POLG2/IGF1/GNMT/MYBBP1A/SDHAF2/UQCRHL	42
BP	GO:0002292	T cell differentiation involved in immune response	12/2306	68/18670	0.128	0.3235	0.2489	NFKBIZ/ZC3H12A/IL6/RELB/RIPK2/IL18R1/MYB/IL4R/STAT6/BCL3/GATA3/STAT3	12
BP	GO:0046323	glucose import	12/2306	68/18670	0.128	0.3235	0.2489	PID1/HK2/SORT1/IRS1/ENPP1/ADIPOR2/SESN2/TNF/APPL2/PTPN11/IGF1/SIRT6	12
BP	GO:0050891	multicellular organismal water homeostasis	12/2306	68/18670	0.128	0.3235	0.2489	AKR1B1/CLDN1/UGCG/KRT16/ADCY7/RAB11FIP2/ADCY9/HAS2/ADCY3/TP63/SCNN1A/FLG	12
BP	GO:0051965	positive regulation of synapse assembly	12/2306	68/18670	0.128	0.3235	0.2489	THBS2/EEF2K/OXTR/SEMA4D/TPBG/FLRT2/BHLHB9/FLRT3/LRRN1/SLITRK4/AMIGO3/LRRN3	12
BP	GO:0046390	ribose phosphate biosynthetic process	44/2306	300/18670	0.1282	0.3239	0.2492	PID1/PRPS1/PPARGC1A/SLC2A6/PYGL/HK2/PRPS1L1/ACACB/ELOVL5/ENO2/ADPGK/NUP133/AK1/SCD/ELOVL7/AMPD3/PGM2L1/ACAT1/PPT1/ADCY7/ACACA/NME5/ACSL5/CBR4/ADCY9/ADCY3/ELOVL2/IMPDH2/PPCS/HSD17B12/PDHB/PAPSS1/GUK1/PGAM4/NPR2/PDK3/NPPA/NUP35/IGF1/STAT3/ALDOC/P2RX7/SIRT6/ELOVL3	44
BP	GO:0030041	actin filament polymerization	28/2306	182/18670	0.1291	0.3261	0.2509	ICAM1/ARPC1A/DBN1/CDC42EP1/ARHGAP18/ACTR3/CDC42EP3/SLIT2/MYADM/ARHGAP28/FMN2/RDX/TTC17/ARPC2/CAPZA2/ARF6/ARF1/PFN2/EPS8/GSN/DIAPH1/PRKCD/GMFB/MIR214/ACTR2/TMOD2/PLEKHG2/MAGEL2	28
BP	GO:0006664	glycolipid metabolic process	18/2306	110/18670	0.1292	0.3261	0.2509	KIT/ST8SIA1/ESYT1/B4GALT3/UGCG/PIGV/A4GALT/NAGA/GLA/GLB1/ITGB8/UGT8/ALDH5A1/MPPE1/PRKCD/PIGK/PIGS/ST3GAL4	18
BP	GO:0001960	negative regulation of cytokine-mediated signaling pathway	13/2306	75/18670	0.1293	0.3261	0.2509	CCL5/IL6/PARP14/IRAK3/SLIT2/ADAR/ROBO1/MIR125B1/GAS6/PPARG/PYDC2/ZNF675/PELI3	13
BP	GO:0043242	negative regulation of protein complex disassembly	13/2306	75/18670	0.1293	0.3261	0.2509	MID1/LIMA1/IRAK3/RDX/PLEKHH2/CAPZA2/EPS8/GSN/TNF/TMOD2/TAOK1/MID1IP1/CAMSAP1	13
BP	GO:0051702	interaction with symbiont	14/2306	82/18670	0.13	0.3277	0.2522	CXCL6/ZC3H12A/CCL5/CCL8/FBXL2/RAB9A/CALM1/CCL3/EIF2AK4/IGF2R/CALM2/PTX3/ZNF639/NUCKS1	14
BP	GO:0030516	regulation of axon extension	16/2306	96/18670	0.1302	0.328	0.2523	NTN1/ZFYVE27/DBN1/VEGFA/PAK1/BMPR2/RUFY3/SEMA4D/IFRD1/CDK5/WNT5A/GDI1/RTN4/ABL1/SEMA4F/CDH4	16
BP	GO:0097327	response to antineoplastic agent	16/2306	96/18670	0.1302	0.328	0.2523	ZC3H12A/ICAM1/CLDN1/DAXX/FOXO1/CFLAR/EDN1/MAPK13/SRD5A1/SMYD3/ERRFI1/GJB2/ABCC2/ASS1/ASNS/CPS1	16
BP	GO:0032602	chemokine production	15/2306	89/18670	0.1303	0.328	0.2524	CXCL6/IL6/IL1B/RIPK2/IL33/IL4R/KLF4/MBP/SIRPA/SNAI2/WNT5A/HAVCR2/TNF/TLR3/TICAM1	15
BP	GO:0038093	Fc receptor signaling pathway	36/2306	241/18670	0.1304	0.3281	0.2524	PSME2/NFKB1/PSMA6/PSMB10/KIT/PSMB8/ARPC1A/PSMB7/PSME1/PAK1/PSMB9/ACTR3/FYN/CALM1/PSMA3/PIK3R2/MAP3K1/PSMA1/PSMB2/ARPC2/PSMB3/ACTB/APPL2/PRKCD/PSMA8/PPP3CA/ABL1/BCL10/MYO10/ACTR2/PSME4/CDC42/PSMB5/ACTG1/PSMF1/WASF2	36
BP	GO:0042593	glucose homeostasis	36/2306	241/18670	0.1304	0.3281	0.2524	ICAM1/ERN1/OAS1/PPARGC1A/BACE2/PYGL/FOXO1/HK2/IRS1/CYBA/PIK3R2/TCF7L2/RAB11FIP2/SESN3/ADIPOR2/LRP5/SIRT1/KCNB1/SESN2/APPL2/DYNLL1/BRSK2/CEBPA/PPP3CA/PDK3/NUCKS1/GAS6/PPARG/PTPN11/NCOA5/STAT3/SRI/FOXO4/SIRT6/RMI1/ADRA2A	36
BP	GO:0035264	multicellular organism growth	23/2306	146/18670	0.131	0.3288	0.253	CSF1/ARID5B/KLF2/WWTR1/FTO/PDE4D/GHR/ERCC2/BBS2/GDF5/GAMT/GDF15/CDKN1C/SH3PXD2B/ATP8A2/SOCS2/ADARB1/PTPN11/ANKRD11/IGF1/STAT3/TBL1XR1/RMI1	23
BP	GO:0045834	positive regulation of lipid metabolic process	23/2306	146/18670	0.131	0.3288	0.253	PTGS2/IL1B/PPARGC1A/KIT/FGF2/PDGFRB/ELOVL5/RDH10/RAB38/FABP3/IRS1/CPT1A/ABCD1/ADORA1/TNFAIP8L3/RGN/TNF/ABHD5/PRKCD/NSMAF/PPARG/MID1IP1/CAPN2	23
BP	GO:0030850	prostate gland development	9/2306	48/18670	0.1311	0.3288	0.253	BMP4/RXRA/WNT5A/NKX3-1/SULF1/TP63/TNC/FGF10/CYP19A1	9
BP	GO:0055023	positive regulation of cardiac muscle tissue growth	9/2306	48/18670	0.1311	0.3288	0.253	FGF2/PIM1/EDN1/GATA6/YAP1/MEF2C/MIR19B2/MIR199A2/IGF1	9
BP	GO:0060324	face development	9/2306	48/18670	0.1311	0.3288	0.253	ARID5B/ALDH1A3/COL1A1/RAB3GAP1/CRISPLD2/WNT5A/CRISPLD1/PTPN11/ANKRD11	9
BP	GO:0072666	establishment of protein localization to vacuole	9/2306	48/18670	0.1311	0.3288	0.253	TNFAIP3/GNPTAB/VPS37D/GCC2/VPS36/VPS37C/VAMP7/M6PR/NEDD4	9
BP	GO:0090199	regulation of release of cytochrome c from mitochondria	9/2306	48/18670	0.1311	0.3288	0.253	BID/PDCD5/PPIF/LMNA/PMAIP1/MMP9/BCL2L1/FAM162A/IGF1	9
BP	GO:1903727	positive regulation of phospholipid metabolic process	9/2306	48/18670	0.1311	0.3288	0.253	KIT/FGF2/PDGFRB/RAB38/FABP3/IRS1/TNFAIP8L3/PRKCD/CAPN2	9
BP	GO:0006101	citrate metabolic process	7/2306	35/18670	0.133	0.3327	0.256	ACO1/IDH1/FH/PDHB/SDHD/SUCLA2/SDHAF2	7
BP	GO:0009262	deoxyribonucleotide metabolic process	7/2306	35/18670	0.133	0.3327	0.256	CMPK2/NUDT18/ADA/NUDT1/CDADC1/GUK1/MBD4	7
BP	GO:0032689	negative regulation of interferon-gamma production	7/2306	35/18670	0.133	0.3327	0.256	ZC3H12A/IL33/PDCD1LG2/AXL/HAVCR2/GATA3/GAS6	7
BP	GO:0033144	negative regulation of intracellular steroid hormone receptor signaling pathway	7/2306	35/18670	0.133	0.3327	0.256	DAB2/LBH/ARNTL/SIRT1/TP63/NCOR2/PER1	7
BP	GO:0034142	toll-like receptor 4 signaling pathway	7/2306	35/18670	0.133	0.3327	0.256	NFKBIA/TNFAIP3/RIPK2/TNIP3/RAB11FIP2/WDFY1/APPL2	7
BP	GO:0098751	bone cell development	7/2306	35/18670	0.133	0.3327	0.256	KIT/MEIS1/FLI1/FBN1/PTPN11/PIP4K2A/WASF2	7
BP	GO:1990774	tumor necrosis factor secretion	7/2306	35/18670	0.133	0.3327	0.256	ZC3H12A/IFIH1/IFNGR1/DDX58/AKAP12/WNT5A/HAVCR2	7
BP	GO:0051169	nuclear transport	50/2306	346/18670	0.1331	0.3328	0.2561	NFKBIA/ZC3H12A/PTGS2/IL1B/RAB23/MX2/YTHDC1/LZTS2/BMP4/PPP1R12A/NUP133/LMNA/DDX20/PIK3R2/UBR5/TCF7L2/CPSF2/ARNTL/NXF1/KPNA3/CPSF6/CDK5/RPAIN/TXN/RANBP3L/APPL2/SP100/DUSP16/PRKCD/IWS1/PPP3CA/CTDSPL2/NXT1/GAS6/PKIG/HTATIP2/CDKN1A/PTPN11/KPNA2/RANBP17/NUP35/ANP32C/FERMT1/CBLB/STAT3/NEDD4/NUP62CL/CHP2/XPO7/DDX19A	50
BP	GO:0019318	hexose metabolic process	37/2306	249/18670	0.1336	0.3338	0.2568	AKR1B1/OAS1/PPARGC1A/C1QTNF1/FOXO1/HK2/PPP1R3F/ACACB/GALM/ENO2/ADPGK/COX11/IRS1/NFE2L1/PGM2L1/DYRK2/GLB1/PHLDA2/ENPP1/PMAIP1/CPT1A/KAT2B/NISCH/LRP5/SIRT1/RGN/SESN2/TNF/PDHB/ALDH5A1/DUSP12/PDK3/SLC35B4/SIK1/IGF1/GNMT/ALDOC	37
BP	GO:0002886	regulation of myeloid leukocyte mediated immunity	10/2306	55/18670	0.1347	0.3356	0.2582	CXCL6/C3/HLA-E/IL4R/DDX58/SNX4/STXBP1/VAMP7/NPPA/TICAM1	10
BP	GO:0006576	cellular biogenic amine metabolic process	10/2306	55/18670	0.1347	0.3356	0.2582	KYNU/SAT1/IDO1/SMOX/HNMT/PRG3/MOXD1/AADAT/ALDH7A1/DHPS	10
BP	GO:0042306	regulation of protein import into nucleus	10/2306	55/18670	0.1347	0.3356	0.2582	ZC3H12A/PTGS2/RAB23/BMP4/PIK3R2/UBR5/PRKCD/PKIG/FERMT1/CHP2	10
BP	GO:0043113	receptor clustering	10/2306	55/18670	0.1347	0.3356	0.2582	SLC7A11/SSH1/ITGA4/CDK5/LHFPL4/GSN/DLG4/DVL1/CRKL/RER1	10
BP	GO:0061098	positive regulation of protein tyrosine kinase activity	10/2306	55/18670	0.1347	0.3356	0.2582	CCL5/EREG/FYN/NEDD9/TGFA/ADORA1/DLG4/GAS6/DVL2/ADRA2A	10
BP	GO:0097120	receptor localization to synapse	10/2306	55/18670	0.1347	0.3356	0.2582	DBN1/GPC4/STX3/SNAP47/KIF17/VPS35/DLG4/NPTN/CNIH2/GRIPAP1	10
BP	GO:2000242	negative regulation of reproductive process	10/2306	55/18670	0.1347	0.3356	0.2582	LIF/BMP4/ADA/WNT5A/NKX3-1/SULF1/ZP2/NPR2/ARHGDIB/IGF1	10
BP	GO:0030326	embryonic limb morphogenesis	20/2306	125/18670	0.1351	0.3362	0.2586	MBNL1/PITX1/RECK/BMP4/RDH10/HOXA11/MSX2/HOXA10/TGFB2/HOXD9/GDF5/GNA12/WNT5A/TP63/FBXW4/OSR2/RSPO2/HOXA9/OSR1/TBX3	20
BP	GO:0031929	TOR signaling	20/2306	125/18670	0.1351	0.3362	0.2586	SIK3/SESN1/FNIP2/CCDC88A/FNIP1/SH3BP4/ARNTL/SESN3/UBR1/GNA12/SIRT1/ARAF/SESN2/GATA3/KPTN/GAS6/ROS1/SIK1/MIR199A2/PRR5	20
BP	GO:0035113	embryonic appendage morphogenesis	20/2306	125/18670	0.1351	0.3362	0.2586	MBNL1/PITX1/RECK/BMP4/RDH10/HOXA11/MSX2/HOXA10/TGFB2/HOXD9/GDF5/GNA12/WNT5A/TP63/FBXW4/OSR2/RSPO2/HOXA9/OSR1/TBX3	20
BP	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	20/2306	125/18670	0.1351	0.3362	0.2586	CCL2/CDK6/FHL1/PLK2/RPA2/PKD2/CCND1/KLF4/PRMT1/GJC2/CARM1/CDKN2C/BTG2/MIR137/ARID3A/CNOT8/CDK2AP2/CTDSP2/CDKN1A/TFDP1	20
BP	GO:0033500	carbohydrate homeostasis	36/2306	242/18670	0.1358	0.3378	0.2599	ICAM1/ERN1/OAS1/PPARGC1A/BACE2/PYGL/FOXO1/HK2/IRS1/CYBA/PIK3R2/TCF7L2/RAB11FIP2/SESN3/ADIPOR2/LRP5/SIRT1/KCNB1/SESN2/APPL2/DYNLL1/BRSK2/CEBPA/PPP3CA/PDK3/NUCKS1/GAS6/PPARG/PTPN11/NCOA5/STAT3/SRI/FOXO4/SIRT6/RMI1/ADRA2A	36
BP	GO:0017156	calcium ion regulated exocytosis	24/2306	154/18670	0.1363	0.3388	0.2607	ADORA2A/STX3/BACE1/RAB3GAP1/CDK5/KCNB1/SNAP47/RAB3A/SYT4/ARF1/PREPL/PFN2/DGKI/ATP2A2/SNPH/STXBP1/SYT1/GRIN3A/VAMP7/NAPB/DVL1/P2RX7/PPFIA3/ADRA2A	24
BP	GO:0010830	regulation of myotube differentiation	11/2306	62/18670	0.137	0.3402	0.2618	CXCL10/CFLAR/IL4R/CXCL9/DMPK/FLOT1/EHD1/GDF15/MIR1-2/SIK1/CAPN2	11
BP	GO:0055025	positive regulation of cardiac muscle tissue development	11/2306	62/18670	0.137	0.3402	0.2618	FGF2/BMP4/PIM1/EDN1/GATA6/YAP1/MEF2C/MIR19B2/MIR1-2/MIR199A2/IGF1	11
BP	GO:1902305	regulation of sodium ion transmembrane transport	11/2306	62/18670	0.137	0.3402	0.2618	CNKSR3/GPD1L/CAMK2D/ANK3/HECW2/ARF1/YWHAH/ACTN4/SNTA1/OSR1/NEDD4	11
BP	GO:0007409	axonogenesis	66/2306	468/18670	0.1374	0.3409	0.2623	TUBB3/NEXN/ZSWIM4/NTN1/PIK3CD/PRKCA/ZFYVE27/SIPA1L1/DBN1/AUTS2/VEGFA/PAK1/VCL/FYN/SLIT2/BMPR2/DOK5/ANK3/RUFY3/ITGA4/SEMA4D/MAP1A/CHN1/FLOT1/EFNB1/FLRT2/IFRD1/ROBO1/CDK5/WNT5A/ENAH/RAB3A/ACTB/ATL1/FLRT3/BRSK2/ETV1/NUMBL/SLITRK4/PTPRM/ATP8A2/PLXND1/STXBP1/GDI1/GATA3/CRMP1/ADARB1/RTN4/EXT1/DOK4/NPTN/ABL1/YTHDF1/PTPN11/EPHA1/FEZ2/PALLD/SEMA4F/MYH10/CDH4/DVL1/MYCBP2/RAPH1/USP9X/PICALM/NFIB	66
BP	GO:1903509	liposaccharide metabolic process	18/2306	111/18670	0.1374	0.3409	0.2623	KIT/ST8SIA1/ESYT1/B4GALT3/UGCG/PIGV/A4GALT/NAGA/GLA/GLB1/ITGB8/UGT8/ALDH5A1/MPPE1/PRKCD/PIGK/PIGS/ST3GAL4	18
BP	GO:0006892	post-Golgi vesicle-mediated transport	17/2306	104/18670	0.1383	0.3429	0.2638	SYS1/EPS15/SORT1/ANK3/WIPI1/BBS2/OPTN/ARF1/PREPL/OSBPL5/ARF3/CCDC93/KLHL20/VAMP7/STEAP2/RAB31/VAMP5	17
BP	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	17/2306	104/18670	0.1383	0.3429	0.2638	BID/TNFRSF1B/BCL2L2/CD44/FNIP2/DYRK2/HIPK2/SNAI2/POLB/BCL3/SIRT1/BCL2L1/TP63/TNF/TOPORS/ABL1/CDKN1A	17
BP	GO:0036465	synaptic vesicle recycling	12/2306	69/18670	0.1385	0.3429	0.2638	PPP3CC/ROCK1/VAMP4/CDK5/RAB3A/ARF6/ACTB/SYT1/TOR1A/ACTG1/GRIPAP1/PICALM	12
BP	GO:0051865	protein autoubiquitination	12/2306	69/18670	0.1385	0.3429	0.2638	SH3RF1/TRIM37/ITCH/DDB2/RNF141/TRAF2/TRIM21/UBE2T/RNF4/SH3RF2/UBE4B/BFAR	12
BP	GO:0055008	cardiac muscle tissue morphogenesis	12/2306	69/18670	0.1385	0.3429	0.2638	BMP2/RXRA/ACTC1/MYOM1/TGFB2/WNT5A/MYOM3/FKBP1A/MYH6/ENG/UBE4B/SIRT6	12
BP	GO:0007044	cell-substrate junction assembly	16/2306	97/18670	0.139	0.3429	0.2638	CORO1C/VEGFA/ROCK1/KRT14/THBS1/TRIP6/ITGA2/DUSP3/PHLDB2/FERMT2/COL16A1/SDC4/ABL1/ROCK2/ITGA6/TLN1	16
BP	GO:0043255	regulation of carbohydrate biosynthetic process	16/2306	97/18670	0.139	0.3429	0.2638	NFKB1/PPARGC1A/FOXO1/PPP1R3F/IRS1/DYRK2/ENPP1/CLTC/KAT2B/HAS2/SIRT1/SESN2/SLC35B4/SIK1/IGF1/GNMT	16
BP	GO:0090630	activation of GTPase activity	16/2306	97/18670	0.139	0.3429	0.2638	TBC1D2/SIPA1L1/CORO1C/ARHGEF10/NEDD9/TBC1D4/RABGAP1/TBC1D22B/WNT5A/EVI5L/PLEKHG4/TBC1D9B/EPHA1/TBC1D10C/TBC1D8/CRKL	16
BP	GO:0019674	NAD metabolic process	13/2306	76/18670	0.1393	0.3429	0.2638	NAMPT/PTGS2/GPD1L/KYNU/IDO1/HK2/ENO2/ADPGK/PGM2L1/NNMT/PARP9/LDHB/ALDOC	13
BP	GO:0046902	regulation of mitochondrial membrane permeability	13/2306	76/18670	0.1393	0.3429	0.2638	BID/PPP3CC/HK2/PPIF/PMAIP1/BCL2L1/TP63/ACAA2/YWHAH/TMEM14A/TFDP1/STAT3/EYA2	13
BP	GO:0140056	organelle localization by membrane tethering	26/2306	169/18670	0.1394	0.3429	0.2638	AHI1/ESYT1/STX3/STX6/SCFD2/DCTN1/CSNK1E/CEP290/CEP250/OFD1/KCNB1/RAB3A/CEP78/DYNLL1/TMEM216/SNPH/STXBP1/SYT1/STX16/MARK4/TSNARE1/DCTN3/CEP63/PPFIA3/VPS45/NPHP1	26
BP	GO:0030641	regulation of cellular pH	15/2306	90/18670	0.1395	0.3429	0.2638	ATP6V1E2/ATP6V0B/RAB38/ATP6V0E2/MAFG/PPT1/TMEM175/SLAMF8/DMXL1/SLC26A3/ATP1A4/ROGDI/ATP6V1E1/SLC9A9/TMEM165	15
BP	GO:0031058	positive regulation of histone modification	15/2306	90/18670	0.1395	0.3429	0.2638	IL1B/LIF/PPARGC1A/JARID2/AUTS2/VEGFA/RNF20/MYB/LMNA/TET1/SNAI2/RPS6KA4/SIRT1/AKAP8/GATA3	15
BP	GO:1903035	negative regulation of response to wounding	15/2306	90/18670	0.1395	0.3429	0.2638	SERPINB2/FGF2/C1QTNF1/PLAU/THBS1/UBASH3B/EDN1/SIGLEC10/PHLDB2/ABAT/PRKCD/SERPINE1/DUSP10/CDKN1A/SERPINF2	15
BP	GO:0071277	cellular response to calcium ion	14/2306	83/18670	0.1396	0.3429	0.2638	SLC25A24/EEF2K/PPIF/CAMK2D/PKD2/EDN1/CPNE3/MEF2C/JUNB/WNT5A/SYT4/SYT1/MCOLN1/CHP2	14
BP	GO:1901879	regulation of protein depolymerization	14/2306	83/18670	0.1396	0.3429	0.2638	MID1/LIMA1/RDX/DSTN/PLEKHH2/MAP1A/CAPZA2/EPS8/GSN/PDXP/TMOD2/TAOK1/MID1IP1/CAMSAP1	14
BP	GO:0010559	regulation of glycoprotein biosynthetic process	8/2306	42/18670	0.1396	0.3429	0.2638	BACE2/IL15/TCF7L2/HBEGF/SOAT1/RAMP1/ACOT8/IGF1	8
BP	GO:0051154	negative regulation of striated muscle cell differentiation	8/2306	42/18670	0.1396	0.3429	0.2638	BMP2/CXCL10/CFLAR/PAK1/RGS2/RGS4/MIR199A2/FZD7	8
BP	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	8/2306	42/18670	0.1396	0.3429	0.2638	ZC3H12A/ISG20/EXOSC6/PDE12/REXO2/DIS3L/CNOT8/ANGEL2	8
BP	GO:0097028	dendritic cell differentiation	8/2306	42/18670	0.1396	0.3429	0.2638	CSF2/RELB/CEBPB/BATF3/AXL/UBD/HLA-G/GAS6	8
BP	GO:1901031	regulation of response to reactive oxygen species	8/2306	42/18670	0.1396	0.3429	0.2638	GPR37L1/SESN1/GCH1/SESN3/RGN/SESN2/TXN/TNF	8
BP	GO:0035725	sodium ion transmembrane transport	22/2306	140/18670	0.1397	0.3429	0.2638	CNKSR3/GPD1L/SLC20A2/CAMK2D/PKD2/ANK3/SLC12A2/SLC3A2/SLC28A3/HECW2/HCN4/TPCN1/SHROOM2/ARF1/YWHAH/ACTN4/SNTA1/SCNN1A/ATP1A4/OSR1/NEDD4/SLC9A9	22
BP	GO:0000303	response to superoxide	6/2306	29/18670	0.1399	0.3429	0.2638	SOD2/GCH1/RGN/ADPRHL2/TNF/GLRX2	6
BP	GO:0003016	respiratory system process	6/2306	29/18670	0.1399	0.3429	0.2638	GLS/FTO/ADH5/ADORA1/RAB3A/TSHZ3	6
BP	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling	6/2306	29/18670	0.1399	0.3429	0.2638	GSTO1/CALM1/CAMK2D/CALM2/ATP2A2/MIR1-2	6
BP	GO:0021884	forebrain neuron development	6/2306	29/18670	0.1399	0.3429	0.2638	SLIT2/LHX8/ROBO1/WNT5A/UBB/DCLK2	6
BP	GO:0042226	interleukin-6 biosynthetic process	6/2306	29/18670	0.1399	0.3429	0.2638	IL1B/CEBPB/EREG/TNF/BCL10/STAT3	6
BP	GO:0044550	secondary metabolite biosynthetic process	6/2306	29/18670	0.1399	0.3429	0.2638	SLC7A11/MC1R/TRPC1/CYP1A2/WNT5A/BDH2	6
BP	GO:0045822	negative regulation of heart contraction	6/2306	29/18670	0.1399	0.3429	0.2638	ZC3H12A/PDE4D/ADORA1/ATP2A2/PDE5A/SRI	6
BP	GO:0048261	negative regulation of receptor-mediated endocytosis	6/2306	29/18670	0.1399	0.3429	0.2638	ANKRD13A/SDCBP/ARF6/DLG4/MIR199A2/PICALM	6
BP	GO:1900181	negative regulation of protein localization to nucleus	6/2306	29/18670	0.1399	0.3429	0.2638	RAB23/LZTS2/TRIM29/PKIG/FERMT1/DCLK2	6
BP	GO:0009152	purine ribonucleotide biosynthetic process	41/2306	280/18670	0.1401	0.3431	0.264	PID1/PPARGC1A/SLC2A6/HK2/ACACB/ELOVL5/ENO2/ADPGK/NUP133/AK1/SCD/ELOVL7/AMPD3/PGM2L1/ACAT1/PPT1/ADCY7/ACACA/NME5/ACSL5/CBR4/ADCY9/ADCY3/ELOVL2/IMPDH2/PPCS/HSD17B12/PDHB/PAPSS1/GUK1/PGAM4/NPR2/PDK3/NPPA/NUP35/IGF1/STAT3/ALDOC/P2RX7/SIRT6/ELOVL3	41
BP	GO:0016236	macroautophagy	43/2306	295/18670	0.1403	0.3435	0.2642	RIPK2/RAB23/ERN1/SQSTM1/SESN1/GABARAPL1/KLHL3/TP53INP2/ATP6V1E2/ATP6V0B/PIM2/CHMP4B/NRBP2/ATP6V0E2/WIPI1/RAB3GAP1/VPS37D/VPS36/VPS37C/TP53INP1/SESN3/RNF5/CDK5/SIRT1/OPTN/ATG7/VPS35/SESN2/PAFAH1B2/DYNLL1/PRKAB2/WDR45/LGALS8/VDAC1/POLDIP2/MCOLN1/PACS2/PIP4K2A/FEZ2/ATP13A2/NEDD4/ATP6V1E1/VPS26A	43
BP	GO:0050768	negative regulation of neurogenesis	43/2306	295/18670	0.1403	0.3435	0.2642	IL6/GPR37L1/IL1B/ID2/NTN1/MEIS1/DENND5A/PLK2/SLIT2/IRX3/RUFY3/EIF2AK4/DPYSL3/DIXDC1/SEMA4D/LPAR1/DAAM2/CARM1/ASCL2/IFRD1/CDK5/WNT5A/ARF6/SYT4/HES5/MIR137/TNF/YWHAH/APPL2/HOOK3/GDI1/ASAP1/CRMP1/RTN4/PPP3CA/DUSP10/ID3/SEMA4F/MIB1/STAT3/MYLIP/NGEF/PRTG	43
BP	GO:0006109	regulation of carbohydrate metabolic process	31/2306	206/18670	0.1414	0.346	0.2662	NFKB1/PPARGC1A/C1QTNF1/SLC2A6/FOXO1/PPP1R3F/ACACB/COX11/IRS1/NUP133/NFE2L1/DYRK2/PHLDA2/ENPP1/PMAIP1/CLTC/KAT2B/HAS2/SIRT1/RGN/SESN2/DUSP12/PDK3/SLC35B4/SIK1/NUP35/IGF1/GNMT/STAT3/P2RX7/SIRT6	31
BP	GO:2000045	regulation of G1/S transition of mitotic cell cycle	28/2306	184/18670	0.1418	0.3467	0.2667	BID/PSME2/CCL2/ID2/CDK6/FHL1/PSME1/PLK2/RPA2/PKD2/CCND1/KLF4/PRMT1/RDX/GJC2/CARM1/CDKN2C/BTG2/MIR137/ARID3A/CNOT8/CDK2AP2/MIR214/CTDSP2/CDKN1A/FGF10/TFDP1/MEPCE	28
BP	GO:1902652	secondary alcohol metabolic process	24/2306	155/18670	0.1434	0.3467	0.2667	CH25H/ABCA1/INSIG2/OSBPL1A/ACACB/LIMA1/RXRA/NFE2L1/SCD/CYP27B1/TM7SF2/ACAT2/ACACA/NPC1L1/SOAT1/ACAA2/OSBPL5/HSD3B7/CLN8/HSD17B7/CEBPA/GPAM/IDI1/SULT2B1	24
BP	GO:0045010	actin nucleation	9/2306	49/18670	0.144	0.3467	0.2667	ARPC1A/ACTR3/FMN2/ARPC2/ARF1/GSN/GMFB/ACTR2/MAGEL2	9
BP	GO:0060042	retina morphogenesis in camera-type eye	9/2306	49/18670	0.144	0.3467	0.2667	AHI1/IRX5/HIPK2/LRP5/FJX1/TOPORS/PTPRM/ATP8A2/RDH13	9
BP	GO:0071715	icosanoid transport	9/2306	49/18670	0.144	0.3467	0.2667	IL1B/BDKRB2/PLA2G4A/EDN1/ABCC1/PLA2G12A/ABCC2/NMUR2/P2RX7	9
BP	GO:1901571	fatty acid derivative transport	9/2306	49/18670	0.144	0.3467	0.2667	IL1B/BDKRB2/PLA2G4A/EDN1/ABCC1/PLA2G12A/ABCC2/NMUR2/P2RX7	9
BP	GO:1903018	regulation of glycoprotein metabolic process	9/2306	49/18670	0.144	0.3467	0.2667	BACE2/IL15/TCF7L2/HBEGF/SOAT1/RAMP1/PTX3/ACOT8/IGF1	9
BP	GO:1904707	positive regulation of vascular smooth muscle cell proliferation	9/2306	49/18670	0.144	0.3467	0.2667	ERN1/FGF2/PAK1/EDN1/MMP9/FOXJ2/TNF/MIR214/IGF1	9
BP	GO:0007173	epidermal growth factor receptor signaling pathway	19/2306	119/18670	0.1445	0.3467	0.2667	ITGA1/PLCE1/GPRC5A/EREG/EPS15/RHBDF2/TGFA/HBEGF/SPRY1/ERRFI1/MMP9/DUSP3/ADORA1/ABL1/PTPN11/CDC42/CBLB/RNF126/ADRA2A	19
BP	GO:0051668	localization within membrane	23/2306	148/18670	0.1454	0.3467	0.2667	DBN1/SLC7A11/GPC4/EPS15/NUP133/STX3/SSH1/ITGA4/CDK5/SNAP47/KIF17/VPS35/LHFPL4/GSN/DLG4/NPTN/RALA/RILPL1/CNIH2/DVL1/GRIPAP1/CRKL/RER1	23
BP	GO:0000050	urea cycle	3/2306	11/18670	0.1457	0.3467	0.2667	ASS1/CEBPA/CPS1	3
BP	GO:0000478	endonucleolytic cleavage involved in rRNA processing	3/2306	11/18670	0.1457	0.3467	0.2667	RCL1/UTP20/BOP1	3
BP	GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	3/2306	11/18670	0.1457	0.3467	0.2667	RCL1/UTP20/BOP1	3
BP	GO:0002730	regulation of dendritic cell cytokine production	3/2306	11/18670	0.1457	0.3467	0.2667	DDX58/TLR3/TICAM1	3
BP	GO:0006048	UDP-N-acetylglucosamine biosynthetic process	3/2306	11/18670	0.1457	0.3467	0.2667	GFPT2/NAGK/PGM3	3
BP	GO:0006681	galactosylceramide metabolic process	3/2306	11/18670	0.1457	0.3467	0.2667	B4GALT3/UGT8/ALDH5A1	3
BP	GO:0006857	oligopeptide transport	3/2306	11/18670	0.1457	0.3467	0.2667	SLC15A3/SLC7A11/ABCC1	3
BP	GO:0008655	pyrimidine-containing compound salvage	3/2306	11/18670	0.1457	0.3467	0.2667	TYMP/TK2/DCK	3
BP	GO:0014820	tonic smooth muscle contraction	3/2306	11/18670	0.1457	0.3467	0.2667	EDN1/BBS2/MYLK	3
BP	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	3/2306	11/18670	0.1457	0.3467	0.2667	CSGALNACT1/EXT1/HS2ST1	3
BP	GO:0019371	cyclooxygenase pathway	3/2306	11/18670	0.1457	0.3467	0.2667	PTGS2/PTGES/PTGS1	3
BP	GO:0021670	lateral ventricle development	3/2306	11/18670	0.1457	0.3467	0.2667	CDK6/NUMBL/MYH10	3
BP	GO:0031915	positive regulation of synaptic plasticity	3/2306	11/18670	0.1457	0.3467	0.2667	PTGS2/DBN1/SSH1	3
BP	GO:0031987	locomotion involved in locomotory behavior	3/2306	11/18670	0.1457	0.3467	0.2667	ARRDC3/VPS35/FZD4	3
BP	GO:0032306	regulation of prostaglandin secretion	3/2306	11/18670	0.1457	0.3467	0.2667	IL1B/EDN1/P2RX7	3
BP	GO:0032351	negative regulation of hormone metabolic process	3/2306	11/18670	0.1457	0.3467	0.2667	BMP2/NFKB1/CYP27B1	3
BP	GO:0032494	response to peptidoglycan	3/2306	11/18670	0.1457	0.3467	0.2667	IL6/RIPK2/IRAK3	3
BP	GO:0033089	positive regulation of T cell differentiation in thymus	3/2306	11/18670	0.1457	0.3467	0.2667	IL7R/ADA/ADAM8	3
BP	GO:0033632	regulation of cell-cell adhesion mediated by integrin	3/2306	11/18670	0.1457	0.3467	0.2667	CCL5/ADA/PODXL	3
BP	GO:0034115	negative regulation of heterotypic cell-cell adhesion	3/2306	11/18670	0.1457	0.3467	0.2667	MYADM/KLF4/MBP	3
BP	GO:0035246	peptidyl-arginine N-methylation	3/2306	11/18670	0.1457	0.3467	0.2667	PRMT1/CARM1/PRMT3	3
BP	GO:0040015	negative regulation of multicellular organism growth	3/2306	11/18670	0.1457	0.3467	0.2667	BBS2/GDF15/SOCS2	3
BP	GO:0042482	positive regulation of odontogenesis	3/2306	11/18670	0.1457	0.3467	0.2667	BMP2/CSF1/EDN1	3
BP	GO:0043097	pyrimidine nucleoside salvage	3/2306	11/18670	0.1457	0.3467	0.2667	TYMP/TK2/DCK	3
BP	GO:0043129	surfactant homeostasis	3/2306	11/18670	0.1457	0.3467	0.2667	EPAS1/VEGFA/RCN3	3
BP	GO:0045176	apical protein localization	3/2306	11/18670	0.1457	0.3467	0.2667	SHROOM3/RDX/SHROOM2	3
BP	GO:0045351	type I interferon biosynthetic process	3/2306	11/18670	0.1457	0.3467	0.2667	IRF7/TLR3/TICAM1	3
BP	GO:0046886	positive regulation of hormone biosynthetic process	3/2306	11/18670	0.1457	0.3467	0.2667	IL1B/PPARGC1A/TNF	3
BP	GO:0051024	positive regulation of immunoglobulin secretion	3/2306	11/18670	0.1457	0.3467	0.2667	IL6/IL33/HLA-E	3
BP	GO:0051791	medium-chain fatty acid metabolic process	3/2306	11/18670	0.1457	0.3467	0.2667	CROT/ABHD3/ACADM	3
BP	GO:0060856	establishment of blood-brain barrier	3/2306	11/18670	0.1457	0.3467	0.2667	RECK/MXRA8/ENG	3
BP	GO:0060947	cardiac vascular smooth muscle cell differentiation	3/2306	11/18670	0.1457	0.3467	0.2667	VEGFA/GATA6/MIR1-2	3
BP	GO:0070189	kynurenine metabolic process	3/2306	11/18670	0.1457	0.3467	0.2667	KYNU/IDO1/AADAT	3
BP	GO:0070254	mucus secretion	3/2306	11/18670	0.1457	0.3467	0.2667	CYBA/ADA/ADORA1	3
BP	GO:0070587	regulation of cell-cell adhesion involved in gastrulation	3/2306	11/18670	0.1457	0.3467	0.2667	MYADM/KLF4/MBP	3
BP	GO:0070673	response to interleukin-18	3/2306	11/18670	0.1457	0.3467	0.2667	CLDN1/RIPK2/IL18R1	3
BP	GO:0072070	loop of Henle development	3/2306	11/18670	0.1457	0.3467	0.2667	IRX3/PKD2/HES5	3
BP	GO:0072310	glomerular epithelial cell development	3/2306	11/18670	0.1457	0.3467	0.2667	BMP4/MYO1E/PODXL	3
BP	GO:0072321	chaperone-mediated protein transport	3/2306	11/18670	0.1457	0.3467	0.2667	TIMM8A/CLIP3/TOR1A	3
BP	GO:1900102	negative regulation of endoplasmic reticulum unfolded protein response	3/2306	11/18670	0.1457	0.3467	0.2667	PPP1R15A/DNAJB9/BFAR	3
BP	GO:1900115	extracellular regulation of signal transduction	3/2306	11/18670	0.1457	0.3467	0.2667	GREM2/ZNF653/FBN1	3
BP	GO:1900116	extracellular negative regulation of signal transduction	3/2306	11/18670	0.1457	0.3467	0.2667	GREM2/ZNF653/FBN1	3
BP	GO:1903977	positive regulation of glial cell migration	3/2306	11/18670	0.1457	0.3467	0.2667	CSF1/CCL3/CRKL	3
BP	GO:1905214	regulation of RNA binding	3/2306	11/18670	0.1457	0.3467	0.2667	CARM1/EIF3E/NUCKS1	3
BP	GO:1905383	protein localization to presynapse	3/2306	11/18670	0.1457	0.3467	0.2667	HSPB1/MAP1A/DVL1	3
BP	GO:2000392	regulation of lamellipodium morphogenesis	3/2306	11/18670	0.1457	0.3467	0.2667	PDPN/CORO1C/CD44	3
BP	GO:2000551	regulation of T-helper 2 cell cytokine production	3/2306	11/18670	0.1457	0.3467	0.2667	IL6/RSAD2/GATA3	3
BP	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	3/2306	11/18670	0.1457	0.3467	0.2667	PRR7/FAS/GSN	3
BP	GO:0002065	columnar/cuboidal epithelial cell differentiation	18/2306	112/18670	0.1459	0.3467	0.2667	BMP2/CDK6/CEBPB/BMP4/RXRA/ARNTL/YIPF6/GATA6/WNT5A/TP63/HES5/DLX3/C1GALT1/PRDM1/SERPINE1/ABL1/CDKN1A/ROS1	18
BP	GO:0015918	sterol transport	18/2306	112/18670	0.1459	0.3467	0.2667	NFKBIA/NFKB1/OSBPL10/ABCA1/OSBPL1A/LIMA1/LIPG/ABCA5/NPC1L1/SOAT1/SIRT1/MIR19B2/OSBPL3/OSBPL5/SCP2/PPARG/OSBPL7/GRAMD1A	18
BP	GO:0017158	regulation of calcium ion-dependent exocytosis	18/2306	112/18670	0.1459	0.3467	0.2667	ADORA2A/BACE1/RAB3GAP1/CDK5/KCNB1/RAB3A/SYT4/ARF1/PREPL/PFN2/DGKI/ATP2A2/STXBP1/SYT1/GRIN3A/NAPB/DVL1/ADRA2A	18
BP	GO:0050868	negative regulation of T cell activation	18/2306	112/18670	0.1459	0.3467	0.2667	ZC3H12A/ADORA2A/IRF1/CEBPB/TNFRSF14/PDCD1LG2/IDO1/BMP4/IL4R/SOCS1/LRRC32/MAD1L1/DUSP3/HAVCR2/HLA-G/SDC4/PDE5A/CBFB	18
BP	GO:1990748	cellular detoxification	18/2306	112/18670	0.1459	0.3467	0.2667	SOD2/PTGS2/SESN1/GSTO1/GCH1/TP53INP1/ADH5/CYGB/UBIAD1/RGN/ABCG2/SESN2/TXN/ESD/TNF/HBB/PTGS1/MGST2	18
BP	GO:0009251	glucan catabolic process	5/2306	23/18670	0.1459	0.3467	0.2667	PYGL/CALM1/PGM2L1/PHKB/PHKA2	5
BP	GO:0022410	circadian sleep/wake cycle process	5/2306	23/18670	0.1459	0.3467	0.2667	CSF2/ADORA2A/ADA/SRD5A1/ADORA1	5
BP	GO:0030539	male genitalia development	5/2306	23/18670	0.1459	0.3467	0.2667	SRD5A1/ASB1/LGR4/FGF10/TBX3	5
BP	GO:0032373	positive regulation of sterol transport	5/2306	23/18670	0.1459	0.3467	0.2667	NFKBIA/ABCA1/LIPG/SIRT1/SCP2	5
BP	GO:0032376	positive regulation of cholesterol transport	5/2306	23/18670	0.1459	0.3467	0.2667	NFKBIA/ABCA1/LIPG/SIRT1/SCP2	5
BP	GO:0034695	response to prostaglandin E	5/2306	23/18670	0.1459	0.3467	0.2667	PTGER2/ACACA/AKAP8/PPARG/GNG2	5
BP	GO:0036037	CD8-positive, alpha-beta T cell activation	5/2306	23/18670	0.1459	0.3467	0.2667	SH3RF1/IRF1/HLA-E/SOCS1/CBFB	5
BP	GO:0043950	positive regulation of cAMP-mediated signaling	5/2306	23/18670	0.1459	0.3467	0.2667	PRKCA/GIP/CALM1/MRAP2/CALM2	5
BP	GO:0061436	establishment of skin barrier	5/2306	23/18670	0.1459	0.3467	0.2667	CLDN1/UGCG/KRT16/TP63/FLG	5
BP	GO:0072337	modified amino acid transport	5/2306	23/18670	0.1459	0.3467	0.2667	SLC7A11/SLC38A2/SLC22A4/ABCC1/SLC19A1	5
BP	GO:0099500	vesicle fusion to plasma membrane	5/2306	23/18670	0.1459	0.3467	0.2667	STX3/SNAP47/RAB3A/STXBP1/SYT1	5
BP	GO:2000637	positive regulation of gene silencing by miRNA	5/2306	23/18670	0.1459	0.3467	0.2667	BMP4/ZFP36/WTIP/DDX5/STAT3	5
BP	GO:0001912	positive regulation of leukocyte mediated cytotoxicity	10/2306	56/18670	0.1469	0.3475	0.2674	HLA-E/IL12A/HLA-F/FADD/HLA-A/MICB/HLA-G/P2RX7/HLA-B/HLA-H	10
BP	GO:0010332	response to gamma radiation	10/2306	56/18670	0.1469	0.3475	0.2674	CXCL10/CCL7/CYBA/CRYAB/YAP1/POLB/BCL2L1/GATA3/GTF2H5/CDKN1A	10
BP	GO:0046148	pigment biosynthetic process	10/2306	56/18670	0.1469	0.3475	0.2674	SLC11A2/PRPS1/SLC7A11/NFE2L1/ADA/MC1R/TRPC1/WNT5A/ALAS1/SLC25A39	10
BP	GO:0048488	synaptic vesicle endocytosis	10/2306	56/18670	0.1469	0.3475	0.2674	PPP3CC/ROCK1/VAMP4/CDK5/ARF6/ACTB/SYT1/TOR1A/ACTG1/PICALM	10
BP	GO:0065002	intracellular protein transmembrane transport	10/2306	56/18670	0.1469	0.3475	0.2674	TRAM2/DNAJC19/DNAJC15/GRPEL1/GRPEL2/LONP2/PEX1/CHCHD4/PEX26/TIMM17B	10
BP	GO:0072528	pyrimidine-containing compound biosynthetic process	10/2306	56/18670	0.1469	0.3475	0.2674	PRPS1/TYMP/CMPK2/NME5/CDADC1/GPAM/CPS1/TK2/DCK/LCLAT1	10
BP	GO:0140238	presynaptic endocytosis	10/2306	56/18670	0.1469	0.3475	0.2674	PPP3CC/ROCK1/VAMP4/CDK5/ARF6/ACTB/SYT1/TOR1A/ACTG1/PICALM	10
BP	GO:0032006	regulation of TOR signaling	17/2306	105/18670	0.1471	0.3475	0.2674	SIK3/SESN1/FNIP2/FNIP1/SH3BP4/ARNTL/SESN3/UBR1/GNA12/SIRT1/ARAF/SESN2/KPTN/GAS6/ROS1/SIK1/MIR199A2	17
BP	GO:0006885	regulation of pH	16/2306	98/18670	0.1482	0.3475	0.2674	ATP6V1E2/ATP6V0B/RAB38/ATP6V0E2/MAFG/EDN1/PPT1/TMEM175/SLAMF8/DMXL1/SLC26A3/ATP1A4/ROGDI/ATP6V1E1/SLC9A9/TMEM165	16
BP	GO:0009119	ribonucleoside metabolic process	16/2306	98/18670	0.1482	0.3475	0.2674	RAB23/APOBEC3G/AMPD3/NUDT18/ADA/APOBEC3H/NT5C2/NME5/IMPDH2/GAMT/CDADC1/GUK1/MTAP/PRTFDC1/APOBEC3F/GNMT	16
BP	GO:0050764	regulation of phagocytosis	16/2306	98/18670	0.1482	0.3475	0.2674	IL1B/CCL2/C3/IL15RA/CYBA/IL15/SIRPA/ITGA2/MYO18A/TNF/APPL2/PTX3/GAS6/PPARG/RAB31/SNX3	16
BP	GO:0007369	gastrulation	28/2306	185/18670	0.1485	0.3475	0.2674	BMP4/LAMB1/ITGB5/BMPR2/MYADM/KLF4/HOXA11/ITGA4/MBP/COL5A2/PHLDB1/ITGA2/GATA6/MMP9/LRP5/PHLDB2/WNT5A/SOX7/MIR1-2/EXT1/ARID1A/DVL1/OSR1/DVL2/COL5A1/FZD7/EYA2/ATOH8	28
BP	GO:0002637	regulation of immunoglobulin production	11/2306	63/18670	0.1486	0.3475	0.2674	IL6/IL33/HLA-E/IL4R/CD40/EXOSC6/CLCF1/STAT6/TRAF2/TNF/SASH3	11
BP	GO:0035418	protein localization to synapse	11/2306	63/18670	0.1486	0.3475	0.2674	HSPB1/GPC4/STX3/MAP1A/CDK5/WNT5A/SNAP47/VPS35/DLG4/DVL1/GRIPAP1	11
BP	GO:0042982	amyloid precursor protein metabolic process	11/2306	63/18670	0.1486	0.3475	0.2674	IFNGR1/BACE2/ROCK1/SOAT1/PSENEN/TNF/FKBP1A/ROCK2/TMED10/IGF1/PICALM	11
BP	GO:1904377	positive regulation of protein localization to cell periphery	11/2306	63/18670	0.1486	0.3475	0.2674	SQSTM1/NKD2/STX3/GPSM2/RAB11FIP2/CLIP3/STAC/ARF6/TNF/RER1/EPB41L2	11
BP	GO:0033572	transferrin transport	7/2306	36/18670	0.1486	0.3475	0.2674	ATP6V1E2/ATP6V0B/ATP6V0E2/CLTC/ARHGAP1/MCOLN1/ATP6V1E1	7
BP	GO:0033762	response to glucagon	7/2306	36/18670	0.1486	0.3475	0.2674	ADCY7/GJB2/ADCY9/ADCY3/ABCC2/ASS1/CPS1	7
BP	GO:0034314	Arp2/3 complex-mediated actin nucleation	7/2306	36/18670	0.1486	0.3475	0.2674	ARPC1A/ACTR3/ARPC2/ARF1/GMFB/ACTR2/MAGEL2	7
BP	GO:0050931	pigment cell differentiation	7/2306	36/18670	0.1486	0.3475	0.2674	KIT/RAB38/ENPP1/MITF/MEF2C/RAB32/ANKRD27	7
BP	GO:0090313	regulation of protein targeting to membrane	7/2306	36/18670	0.1486	0.3475	0.2674	PAK1/FYN/ANK3/CDK5/KCNB1/GDI1/VAMP7	7
BP	GO:2000310	regulation of NMDA receptor activity	7/2306	36/18670	0.1486	0.3475	0.2674	CCL2/PPARGC1A/DAPK1/GRIA3/MEF2C/DLG4/CNIH2	7
BP	GO:2000516	positive regulation of CD4-positive, alpha-beta T cell activation	7/2306	36/18670	0.1486	0.3475	0.2674	NFKBIZ/CD83/RIPK2/MYB/IL4R/SOCS1/SASH3	7
BP	GO:0060606	tube closure	15/2306	91/18670	0.149	0.3475	0.2674	BMP4/FZD1/SHROOM3/FZD2/TGFB2/WNT5A/PTK7/ARID1A/SDC4/ABL1/BCL10/RALA/FGF10/DVL1/DVL2	15
BP	GO:0000097	sulfur amino acid biosynthetic process	4/2306	17/18670	0.1493	0.3475	0.2674	MTHFD2L/MTR/BHMT2/MTAP	4
BP	GO:0003184	pulmonary valve morphogenesis	4/2306	17/18670	0.1493	0.3475	0.2674	BMP4/SLIT2/TGFB2/ROBO1	4
BP	GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	4/2306	17/18670	0.1493	0.3475	0.2674	MSX2/TGFB2/SNAI2/ENG	4
BP	GO:0006089	lactate metabolic process	4/2306	17/18670	0.1493	0.3475	0.2674	PNKD/HAGH/LDHB/LDHD	4
BP	GO:0006744	ubiquinone biosynthetic process	4/2306	17/18670	0.1493	0.3475	0.2674	COQ10B/PDSS2/UBIAD1/COQ3	4
BP	GO:0006825	copper ion transport	4/2306	17/18670	0.1493	0.3475	0.2674	SLC11A2/COX17/CUTC/STEAP2	4
BP	GO:0009070	serine family amino acid biosynthetic process	4/2306	17/18670	0.1493	0.3475	0.2674	PSPH/SEPHS1/PSAT1/PHGDH	4
BP	GO:0010715	regulation of extracellular matrix disassembly	4/2306	17/18670	0.1493	0.3475	0.2674	IL6/FSCN1/PDPN/ETS1	4
BP	GO:0015732	prostaglandin transport	4/2306	17/18670	0.1493	0.3475	0.2674	IL1B/EDN1/ABCC2/P2RX7	4
BP	GO:0015919	peroxisomal membrane transport	4/2306	17/18670	0.1493	0.3475	0.2674	ABCD1/LONP2/PEX1/PEX26	4
BP	GO:0021783	preganglionic parasympathetic fiber development	4/2306	17/18670	0.1493	0.3475	0.2674	SIX1/NAV2/HES3/ADARB1	4
BP	GO:0031268	pseudopodium organization	4/2306	17/18670	0.1493	0.3475	0.2674	KIT/CDC42EP1/CDC42EP3/CDC42	4
BP	GO:0032460	negative regulation of protein oligomerization	4/2306	17/18670	0.1493	0.3475	0.2674	CRYAB/VPS35/CRBN/IAPP	4
BP	GO:0033599	regulation of mammary gland epithelial cell proliferation	4/2306	17/18670	0.1493	0.3475	0.2674	CCND1/ROBO1/GATA3/RTN4	4
BP	GO:0035313	wound healing, spreading of epidermal cells	4/2306	17/18670	0.1493	0.3475	0.2674	MSX2/HBEGF/PHLDB2/COL5A1	4
BP	GO:0036149	phosphatidylinositol acyl-chain remodeling	4/2306	17/18670	0.1493	0.3475	0.2674	PLA2G4A/PLA2G4C/PLA2G12A/LCLAT1	4
BP	GO:0042994	cytoplasmic sequestering of transcription factor	4/2306	17/18670	0.1493	0.3475	0.2674	NFKBIA/NFKBIE/PKD2/SRI	4
BP	GO:0043651	linoleic acid metabolic process	4/2306	17/18670	0.1493	0.3475	0.2674	ELOVL5/ELOVL2/ABCD1/ELOVL3	4
BP	GO:0045187	regulation of circadian sleep/wake cycle, sleep	4/2306	17/18670	0.1493	0.3475	0.2674	CSF2/ADORA2A/ADA/ADORA1	4
BP	GO:0046068	cGMP metabolic process	4/2306	17/18670	0.1493	0.3475	0.2674	PDE1A/NPR2/NPPA/PDE5A	4
BP	GO:0046500	S-adenosylmethionine metabolic process	4/2306	17/18670	0.1493	0.3475	0.2674	MAT2A/GAMT/BHMT2/GNMT	4
BP	GO:0050665	hydrogen peroxide biosynthetic process	4/2306	17/18670	0.1493	0.3475	0.2674	FYN/CYBA/CYP1A2/STAT3	4
BP	GO:0061318	renal filtration cell differentiation	4/2306	17/18670	0.1493	0.3475	0.2674	BASP1/BMP4/MYO1E/PODXL	4
BP	GO:0061323	cell proliferation involved in heart morphogenesis	4/2306	17/18670	0.1493	0.3475	0.2674	SIX1/BMP4/BMPR2/PIM1	4
BP	GO:0070242	thymocyte apoptotic process	4/2306	17/18670	0.1493	0.3475	0.2674	BMP4/ADA/WNT5A/ADAM8	4
BP	GO:0072112	glomerular visceral epithelial cell differentiation	4/2306	17/18670	0.1493	0.3475	0.2674	BASP1/BMP4/MYO1E/PODXL	4
BP	GO:1901663	quinone biosynthetic process	4/2306	17/18670	0.1493	0.3475	0.2674	COQ10B/PDSS2/UBIAD1/COQ3	4
BP	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell	4/2306	17/18670	0.1493	0.3475	0.2674	ICAM1/ETS1/ITGA4/TNF	4
BP	GO:2000136	regulation of cell proliferation involved in heart morphogenesis	4/2306	17/18670	0.1493	0.3475	0.2674	SIX1/BMP4/BMPR2/PIM1	4
BP	GO:2001267	regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	4/2306	17/18670	0.1493	0.3475	0.2674	PRR7/FAS/MMP9/GSN	4
BP	GO:0061515	myeloid cell development	12/2306	70/18670	0.1495	0.3475	0.2674	SLC11A2/KIT/MEIS1/KLF2/ERCC2/FLI1/FBN1/PTPN11/PIP4K2A/TSPAN2/ARID4A/WASF2	12
BP	GO:2001259	positive regulation of cation channel activity	12/2306	70/18670	0.1495	0.3475	0.2674	CCL2/CTSS/GSTO1/CALM1/PKD2/ANK3/STAC/CALM2/MIR1-2/STIM1/NPPA/CASQ1	12
BP	GO:0046889	positive regulation of lipid biosynthetic process	14/2306	84/18670	0.1496	0.3475	0.2674	PTGS2/IL1B/PPARGC1A/ELOVL5/RDH10/RAB38/FABP3/ABCD1/RGN/TNF/PRKCD/NSMAF/MID1IP1/CAPN2	14
BP	GO:0050818	regulation of coagulation	14/2306	84/18670	0.1496	0.3475	0.2674	SERPINB2/C1QTNF1/PRKCA/PDPN/PLAU/THBS1/UBASH3B/EDN1/F2R/MIR19B2/ABAT/PRKCD/SERPINE1/SERPINF2	14
BP	GO:0050886	endocrine process	14/2306	84/18670	0.1496	0.3475	0.2674	IL1B/C1QTNF1/CYBA/OXTR/EDN1/INHBB/F2R/NKX3-1/FZD4/GATA3/RAB11FIP1/PTPN11/SERPINF2/TBX3	14
BP	GO:0031397	negative regulation of protein ubiquitination	13/2306	77/18670	0.1498	0.3477	0.2675	TNFAIP3/BAG2/ISG15/PRR7/DNAJA1/FYN/UBR5/CDK5/UBXN1/PRMT3/IVNS1ABP/ABL1/SH3RF2	13
BP	GO:1901224	positive regulation of NIK/NF-kappaB signaling	13/2306	77/18670	0.1498	0.3477	0.2675	IL1B/IL18R1/TRIP6/ZFP91/EDN1/CARD10/TRAF2/HAVCR2/TNF/TNFRSF10B/ACTN4/TLR3/RBCK1	13
BP	GO:0016573	histone acetylation	24/2306	156/18670	0.1507	0.3495	0.2689	IL1B/LIF/BRPF3/PPARGC1A/AUTS2/SET/DR1/KAT2B/SNAI2/MORF4L2/RPS6KA4/YEATS2/SIRT1/MSL1/GATA3/IWS1/SETD5/TAF6L/PER1/GTF3C4/MSL3/ZNF451/TADA3/PHF10	24
BP	GO:0048634	regulation of muscle organ development	24/2306	156/18670	0.1507	0.3495	0.2689	BMP2/FGF2/MEIS1/JARID2/SIX1/BMP4/PAK1/PIM1/EDN1/ARNTL/RGS2/GATA6/YAP1/FLOT1/SIX4/MEF2C/AKIRIN1/MIR19B2/RGS4/DDX5/MIR1-2/MIR199A2/IGF1/FZD7	24
BP	GO:0032368	regulation of lipid transport	20/2306	127/18670	0.1511	0.3504	0.2696	NFKBIA/IL1B/NFKB1/ABCA1/C1QTNF1/MYB/FABP3/THBS1/EDN1/LIPG/SIRT1/MIR19B2/NKX3-1/ATP8A2/PRKCD/SCP2/PPARG/PTPN11/P2RX7/CYP19A1	20
BP	GO:0048592	eye morphogenesis	23/2306	149/18670	0.1529	0.3544	0.2727	AHI1/MEIS1/ALDH1A3/VEGFA/BMP4/IRX5/BCAR3/COL5A2/HIPK2/LRP5/CEP290/WNT5A/SHROOM2/FJX1/FBN1/TOPORS/PTPRM/ATP8A2/ARID1A/PRDM1/RDH13/STAT3/COL5A1	23
BP	GO:0016241	regulation of macroautophagy	26/2306	171/18670	0.1533	0.3551	0.2732	RIPK2/ERN1/SESN1/ATP6V1E2/ATP6V0B/PIM2/CHMP4B/NRBP2/ATP6V0E2/RAB3GAP1/SESN3/RNF5/CDK5/SIRT1/OPTN/VPS35/SESN2/PAFAH1B2/PRKAB2/POLDIP2/PIP4K2A/FEZ2/ATP13A2/NEDD4/ATP6V1E1/VPS26A	26
BP	GO:0051650	establishment of vesicle localization	42/2306	290/18670	0.1535	0.3555	0.2735	ADORA2A/FNBP1L/BET1/STX3/BACE1/WIPI1/ITGA4/RAB3GAP1/TGFA/LIN7A/BBS2/CDK5/SNAP47/RAB3A/SHROOM2/SYT4/ARF1/PREPL/PFN2/DGKI/ATP2A2/ACTN4/SNPH/STXBP1/SYT1/GRIN3A/TMED9/STARD3NL/TOR1A/TRAPPC4/TMED10/AP3S1/VAMP7/NAPB/CNIH2/TRAPPC9/DVL1/P2RX7/SERPINA1/PPFIA3/GRIPAP1/PICALM	42
BP	GO:0003009	skeletal muscle contraction	8/2306	43/18670	0.1541	0.3559	0.2738	GSTO1/DMPK/SYNM/STAC/CHRNB1/ATP2A2/ATP8A2/CASQ1	8
BP	GO:0006904	vesicle docking involved in exocytosis	8/2306	43/18670	0.1541	0.3559	0.2738	STX3/SCFD2/KCNB1/RAB3A/SNPH/STXBP1/PPFIA3/VPS45	8
BP	GO:0010824	regulation of centrosome duplication	8/2306	43/18670	0.1541	0.3559	0.2738	CHMP1B/PLK2/CHMP4B/TRIM37/KAT2B/CHMP5/ROCK2/PDCD6IP	8
BP	GO:0032459	regulation of protein oligomerization	8/2306	43/18670	0.1541	0.3559	0.2738	BID/MMP1/MMP3/CRYAB/PMAIP1/VPS35/CRBN/IAPP	8
BP	GO:0034198	cellular response to amino acid starvation	8/2306	43/18670	0.1541	0.3559	0.2738	SESN1/SLC38A2/FAS/EIF2AK4/SESN3/SESN2/KPTN/CDKN1A	8
BP	GO:0071364	cellular response to epidermal growth factor stimulus	8/2306	43/18670	0.1541	0.3559	0.2738	CFLAR/COL1A1/ZFP36/ZFP36L2/ERRFI1/SNAI2/DUSP3/PTPN11	8
BP	GO:0086004	regulation of cardiac muscle cell contraction	8/2306	43/18670	0.1541	0.3559	0.2738	PDE4D/CAMK2D/HCN4/ADORA1/ATP2A2/MIR1-2/PDE4B/SRI	8
BP	GO:0099054	presynapse assembly	8/2306	43/18670	0.1541	0.3559	0.2738	FZD1/GPC4/WNT5A/VPS35/ARF6/LRFN4/DVL1/PCDH17	8
BP	GO:0038127	ERBB signaling pathway	22/2306	142/18670	0.1551	0.3579	0.2754	ITGA1/PRKCA/PLCE1/GPRC5A/EREG/EPS15/RHBDF2/TGFA/HBEGF/SPRY1/ERRFI1/MMP9/DUSP3/CPNE3/ADORA1/RTN4/ABL1/PTPN11/CDC42/CBLB/RNF126/ADRA2A	22
BP	GO:0046467	membrane lipid biosynthetic process	22/2306	142/18670	0.1551	0.3579	0.2754	ST8SIA1/ELOVL5/B4GALT3/UGCG/PIGV/ELOVL7/A4GALT/CSNK1G2/ELOVL2/UGT8/TNF/CLN8/MPPE1/PRKCD/SGMS2/PIGK/PIGS/NSMAF/P2RX7/SAMD8/ELOVL3/ST3GAL4	22
BP	GO:0072698	protein localization to microtubule cytoskeleton	9/2306	50/18670	0.1576	0.3624	0.2789	MID1/MAP1A/CEP250/HOOK3/DIAPH1/MAPRE2/MARK4/DVL1/SNX10	9
BP	GO:0043648	dicarboxylic acid metabolic process	16/2306	99/18670	0.1577	0.3624	0.2789	KYNU/GLS/MTHFD2L/SLC7A11/IDH1/GLUD1/MTHFD2/FH/AADAT/ASS1/ALDH5A1/ME1/ACOT8/SUCLA2/SLC19A1/ALDH1L2	16
BP	GO:0000305	response to oxygen radical	6/2306	30/18670	0.1578	0.3624	0.2789	SOD2/GCH1/RGN/ADPRHL2/TNF/GLRX2	6
BP	GO:0001782	B cell homeostasis	6/2306	30/18670	0.1578	0.3624	0.2789	TNFAIP3/TNFSF13B/ADA/MEF2C/ABL1/BCL10	6
BP	GO:0001844	protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	6/2306	30/18670	0.1578	0.3624	0.2789	BID/PPP3CC/PMAIP1/TP63/YWHAH/TFDP1	6
BP	GO:0046640	regulation of alpha-beta T cell proliferation	6/2306	30/18670	0.1578	0.3624	0.2789	RIPK2/SH3RF1/IRF1/TNFRSF14/HLA-E/EBI3	6
BP	GO:0048265	response to pain	6/2306	30/18670	0.1578	0.3624	0.2789	GCH1/THBS1/P2RX3/CACNA1B/NMUR2/CAPN2	6
BP	GO:0070168	negative regulation of biomineral tissue development	6/2306	30/18670	0.1578	0.3624	0.2789	ROCK1/CCL3/ENPP1/SRGN/ROCK2/GAS6	6
BP	GO:0070979	protein K11-linked ubiquitination	6/2306	30/18670	0.1578	0.3624	0.2789	CDC16/ANAPC13/UBE2T/RNF4/CDC23/UBE2S	6
BP	GO:0071480	cellular response to gamma radiation	6/2306	30/18670	0.1578	0.3624	0.2789	CYBA/CRYAB/YAP1/BCL2L1/GTF2H5/CDKN1A	6
BP	GO:0090200	positive regulation of release of cytochrome c from mitochondria	6/2306	30/18670	0.1578	0.3624	0.2789	BID/PDCD5/PPIF/PMAIP1/MMP9/FAM162A	6
BP	GO:1904893	negative regulation of STAT cascade	6/2306	30/18670	0.1578	0.3624	0.2789	PARP14/SOCS1/SOCS3/BCL3/MIR125B1/SOCS2	6
BP	GO:1903034	regulation of response to wounding	27/2306	179/18670	0.1578	0.3625	0.2789	TNFAIP3/SERPINB2/FGF2/C1QTNF1/PRKCA/PDPN/PLAU/KLF4/THBS1/UBASH3B/EDN1/HBEGF/F2R/SIGLEC10/PHLDB2/RAB3A/MYLK/ABAT/SYTL4/PRKCD/SERPINE1/DUSP10/CDKN1A/MYH9/MIR199A2/SERPINF2/ADRA2A	27
BP	GO:0019827	stem cell population maintenance	24/2306	157/18670	0.1582	0.3631	0.2794	LIF/KIT/FGF2/FOXO1/LDB2/MED10/KLF4/TET1/LBH/ZFP36L2/YAP1/ASCL2/GNL3/TP63/HES5/HOOK3/ARID1A/MMP24/EPHA1/FGF10/ZNF706/STAT3/FZD7/TBX3	24
BP	GO:0051648	vesicle localization	44/2306	306/18670	0.1586	0.364	0.2801	ADORA2A/FNBP1L/BET1/STX3/BACE1/WIPI1/ITGA4/RAB3GAP1/TGFA/LIN7A/BBS2/CDK5/SNAP47/RAB3A/SHROOM2/SYT4/ARF1/PREPL/PFN2/DGKI/BRSK2/ATP2A2/ACTN4/SNPH/STXBP1/SYT1/GRIN3A/TMED9/STARD3NL/TOR1A/TRAPPC4/TMED10/AP3S1/VAMP7/NAPB/CNIH2/TRAPPC9/DVL1/P2RX7/PCDH17/SERPINA1/PPFIA3/GRIPAP1/PICALM	44
BP	GO:0048008	platelet-derived growth factor receptor signaling pathway	10/2306	57/18670	0.1596	0.366	0.2816	ARID5B/VEGFA/PDGFRB/PDGFRL/MYO1E/PDGFD/PDGFC/ABL1/PTPN11/CBLB	10
BP	GO:0060043	regulation of cardiac muscle cell proliferation	10/2306	57/18670	0.1596	0.366	0.2816	FGF2/MEIS1/JARID2/PIM1/GATA6/YAP1/MEF2C/MIR19B2/MIR1-2/MIR199A2	10
BP	GO:0002028	regulation of sodium ion transport	14/2306	85/18670	0.1599	0.3666	0.2821	CNKSR3/GPD1L/CAMK2D/ANK3/HECW2/ARF1/YWHAH/ACTN4/SNTA1/PER1/SIK1/OSR1/P2RX7/NEDD4	14
BP	GO:0051262	protein tetramerization	26/2306	172/18670	0.1605	0.3677	0.2829	SOD2/CCL5/GLS/ALDH1A3/HINT3/ACACB/GBP5/RXRA/PKD2/CRYZ/ACACA/CBR4/PDSS2/IMPDH2/CPSF6/TP63/CUTC/APPL2/CD79A/ALDH5A1/ME1/FARSB/SBF2/MCOLN1/GNMT/CRTC3	26
BP	GO:0070664	negative regulation of leukocyte proliferation	13/2306	78/18670	0.1606	0.3678	0.283	TNFAIP3/CCL8/CEBPB/TNFRSF14/PDCD1LG2/IDO1/BMP4/LRRC32/MAD1L1/HAVCR2/HLA-G/SDC4/PDE5A	13
BP	GO:0008203	cholesterol metabolic process	23/2306	150/18670	0.1606	0.3678	0.283	CH25H/ABCA1/INSIG2/OSBPL1A/ACACB/LIMA1/RXRA/NFE2L1/SCD/TM7SF2/ACAT2/ACACA/NPC1L1/SOAT1/ACAA2/OSBPL5/HSD3B7/CLN8/HSD17B7/CEBPA/GPAM/IDI1/SULT2B1	23
BP	GO:0043647	inositol phosphate metabolic process	12/2306	71/18670	0.1609	0.3682	0.2833	PLCD3/FGF2/PLCE1/PLCD1/CALM1/NUDT11/IMPA2/PLCB4/ITPKA/INPP5B/IP6K3/INPP1	12
BP	GO:0051057	positive regulation of small GTPase mediated signal transduction	12/2306	71/18670	0.1609	0.3682	0.2833	CSF1/AUTS2/PDGFRB/F2R/LPAR1/ROBO1/DGKI/MAPRE2/FGF10/IGF1/SHOC2/CRKL	12
BP	GO:0001704	formation of primary germ layer	19/2306	121/18670	0.1616	0.3695	0.2843	BMP4/LAMB1/ITGB5/BMPR2/KLF4/HOXA11/ITGA4/COL5A2/ITGA2/GATA6/MMP9/WNT5A/SOX7/MIR1-2/ARID1A/COL5A1/FZD7/EYA2/ATOH8	19
BP	GO:0021700	developmental maturation	41/2306	284/18670	0.1619	0.3701	0.2848	BMP2/ID2/RECK/NFIA/EPAS1/C3/VEGFA/EREG/KLF2/IRX5/POU2F2/RAB38/MTCH1/IL15/MSX2/SEMA4D/ERCC2/TGFB2/AXL/WNT5A/RAB32/RAB3A/SYT4/HES5/CDKN1C/DLG4/STXBP1/CEBPA/SPINK1/GATA3/NPR2/SLC26A3/PPARG/CDKN1A/ANKS1A/BSPH1/FERMT1/IGF1/ANKRD27/PICALM/CBFB	41
BP	GO:0031056	regulation of histone modification	22/2306	143/18670	0.1631	0.3728	0.2868	IL1B/LIF/PPARGC1A/JARID2/AUTS2/VEGFA/RNF20/MYB/SET/CAMK2D/LMNA/TET1/UBR5/SNAI2/RPS6KA4/SIRT1/AKAP8/GATA3/IWS1/SETD5/ZNF451/TADA3	22
BP	GO:0006690	icosanoid metabolic process	18/2306	114/18670	0.1636	0.3737	0.2875	PTGS2/IL1B/PTGES/PLA2G4A/PLA2G4C/CYP2U1/EDN1/PRG3/CYP1A2/ABCC1/DAGLA/SIRT1/DAGLB/PTGS1/MGST2/FAAH2/CYP2C19/CYP2S1	18
BP	GO:0060349	bone morphogenesis	18/2306	114/18670	0.1636	0.3737	0.2875	NAB1/RAB23/INSIG2/BMP4/COL1A1/BMPR2/HOXA11/DHRS3/MSX2/SCARA3/CSGALNACT1/HAS2/LRP5/CARM1/MEF2C/COL6A3/OSR2/SERPINH1	18
BP	GO:0017157	regulation of exocytosis	32/2306	217/18670	0.1643	0.3751	0.2886	ADORA2A/RAB9A/IL4R/HLA-F/BACE1/SNX4/RAB2B/RAB3GAP1/SDCBP/CDK5/KCNB1/RAB3A/SYT4/ARF1/PREPL/PFN2/DGKI/SYTL4/ATP2A2/STXBP5/STXBP1/SYT1/SDC4/GRIN3A/RALA/VAMP7/NPPA/NAPB/ATP13A2/DVL1/PDCD6IP/ADRA2A	32
BP	GO:0042445	hormone metabolic process	34/2306	232/18670	0.1648	0.3753	0.2888	BMP2/AKR1B1/IL1B/NFKB1/DIO2/PPARGC1A/HSD11B1/BACE2/ALDH1A3/AFP/CYP27C1/RDH10/RDH8/DHRS11/DHRS3/SRD5A1/CYP27B1/TCF7L2/GHR/CYP1A2/VDR/HSD17B12/TNF/YWHAH/HSD17B7/CHST8/GATA3/HSD17B6/STARD3NL/RDH13/ADH1C/PTPN11/CYP2S1/CYP19A1	34
BP	GO:0002714	positive regulation of B cell mediated immunity	7/2306	37/18670	0.165	0.3753	0.2888	C3/HLA-E/CD40/EXOSC6/CLCF1/STAT6/TNF	7
BP	GO:0002891	positive regulation of immunoglobulin mediated immune response	7/2306	37/18670	0.165	0.3753	0.2888	C3/HLA-E/CD40/EXOSC6/CLCF1/STAT6/TNF	7
BP	GO:0006623	protein targeting to vacuole	7/2306	37/18670	0.165	0.3753	0.2888	GNPTAB/VPS37D/GCC2/VPS37C/VAMP7/M6PR/NEDD4	7
BP	GO:0043114	regulation of vascular permeability	7/2306	37/18670	0.165	0.3753	0.2888	BDKRB2/ADORA2A/C2CD4B/DDAH1/VEGFA/SLIT2/AKAP12	7
BP	GO:0045777	positive regulation of blood pressure	7/2306	37/18670	0.165	0.3753	0.2888	ID2/PDE4D/NR2F2/CYBA/OXTR/ADH5/ADORA1	7
BP	GO:0051567	histone H3-K9 methylation	7/2306	37/18670	0.165	0.3753	0.2888	JARID2/MYB/LMNA/SETDB2/SIRT1/SETD5/ARID4A	7
BP	GO:1903432	regulation of TORC1 signaling	7/2306	37/18670	0.165	0.3753	0.2888	SIK3/SESN1/FNIP2/FNIP1/SESN3/SESN2/KPTN	7
BP	GO:2000142	regulation of DNA-templated transcription, initiation	7/2306	37/18670	0.165	0.3753	0.2888	BCLAF1/DR1/CAND1/MITF/THRA/SUB1/ZNF451	7
BP	GO:0002407	dendritic cell chemotaxis	5/2306	24/18670	0.1667	0.3768	0.2899	CCL5/IL12A/ARHGEF5/SLAMF8/GAS6	5
BP	GO:0003272	endocardial cushion formation	5/2306	24/18670	0.1667	0.3768	0.2899	MSX2/TGFB2/SNAI2/ROBO1/ENG	5
BP	GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	5/2306	24/18670	0.1667	0.3768	0.2899	GSTO1/CALM1/CAMK2D/CALM2/MIR1-2	5
BP	GO:0032878	regulation of establishment or maintenance of cell polarity	5/2306	24/18670	0.1667	0.3768	0.2899	ROCK1/RUFY3/GSN/GATA3/ROCK2	5
BP	GO:0032897	negative regulation of viral transcription	5/2306	24/18670	0.1667	0.3768	0.2899	CCL5/CCL3/ZFP36/TRIM21/ZNF639	5
BP	GO:0034162	toll-like receptor 9 signaling pathway	5/2306	24/18670	0.1667	0.3768	0.2899	IRAK2/RSAD2/IRAK4/HAVCR2/RTN4	5
BP	GO:0035588	G protein-coupled purinergic receptor signaling pathway	5/2306	24/18670	0.1667	0.3768	0.2899	ADORA2A/P2RY11/ADA/ADORA1/ADORA3	5
BP	GO:0042738	exogenous drug catabolic process	5/2306	24/18670	0.1667	0.3768	0.2899	CYP4B1/CYP2U1/CYP1A2/CYP2C19/CYP2S1	5
BP	GO:0046135	pyrimidine nucleoside catabolic process	5/2306	24/18670	0.1667	0.3768	0.2899	TYMP/APOBEC3G/APOBEC3H/CDADC1/APOBEC3F	5
BP	GO:0046426	negative regulation of JAK-STAT cascade	5/2306	24/18670	0.1667	0.3768	0.2899	PARP14/SOCS1/SOCS3/BCL3/SOCS2	5
BP	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process	5/2306	24/18670	0.1667	0.3768	0.2899	TPST1/ENPP1/SULT1C4/PAPSS1/SULT2B1	5
BP	GO:0050687	negative regulation of defense response to virus	5/2306	24/18670	0.1667	0.3768	0.2899	TSPAN6/ITCH/DHX58/MICB/TRIM38	5
BP	GO:0051220	cytoplasmic sequestering of protein	5/2306	24/18670	0.1667	0.3768	0.2899	NFKBIA/NFKBIE/DBN1/PKD2/SRI	5
BP	GO:0060148	positive regulation of posttranscriptional gene silencing	5/2306	24/18670	0.1667	0.3768	0.2899	BMP4/ZFP36/WTIP/DDX5/STAT3	5
BP	GO:0062009	secondary palate development	5/2306	24/18670	0.1667	0.3768	0.2899	FZD1/LRRC32/FZD2/TGFB2/WNT5A	5
BP	GO:1900078	positive regulation of cellular response to insulin stimulus	5/2306	24/18670	0.1667	0.3768	0.2899	PAK1/IRS1/SIRT1/NUCKS1/PTPN11	5
BP	GO:1903020	positive regulation of glycoprotein metabolic process	5/2306	24/18670	0.1667	0.3768	0.2899	IL15/TCF7L2/SOAT1/RAMP1/IGF1	5
BP	GO:2000209	regulation of anoikis	5/2306	24/18670	0.1667	0.3768	0.2899	SNAI2/PTRH2/TLE1/SIK1/MYBBP1A	5
BP	GO:0010657	muscle cell apoptotic process	16/2306	100/18670	0.1675	0.3782	0.291	SOD2/ZC3H12A/CFLAR/IL12A/CAMK2D/PDE1A/STK4/EDN1/DMPK/SIRT1/MIR19B2/MIR1-2/PPARG/MIR199A2/IGF1/CAPN2	16
BP	GO:0060840	artery development	16/2306	100/18670	0.1675	0.3782	0.291	SIX1/VEGFA/BMP4/PDGFRB/BMPR2/PKD2/TGFB2/HECTD1/ROBO1/NKX3-1/LOXL1/MYLK/PLXND1/PRDM1/ENG/MYH10	16
BP	GO:0045165	cell fate commitment	39/2306	270/18670	0.168	0.3791	0.2916	BMP2/IL6/ID2/PITX1/CEBPB/FGF2/PDPN/SIX1/EPAS1/BMP4/NR2F2/NFE2L1/KLF4/HOXA11/CYLD/TCF7L2/SOX5/MITF/GATA6/WNT5B/STAT6/IFRD1/MEF2C/MIR19B2/WNT5A/HES5/SLAMF8/SH3PXD2B/MIR1-2/GATA3/ZNF521/PRDM1/PPARG/FGF10/OLIG3/STAT3/FZD7/EYA2/TBX3	39
BP	GO:0006639	acylglycerol metabolic process	20/2306	129/18670	0.1681	0.3791	0.2916	GK/LPIN1/PLCE1/C3/INSIG2/SLC22A4/FABP3/LIPG/CPT1A/DAGLA/SIRT1/RGN/DGKI/DAGLB/ABHD5/GPAM/CPS1/PTPN11/SIK1/TBL1XR1	20
BP	GO:0034754	cellular hormone metabolic process	20/2306	129/18670	0.1681	0.3791	0.2916	BMP2/AKR1B1/PPARGC1A/ALDH1A3/AFP/CYP27C1/RDH10/RDH8/DHRS11/DHRS3/SRD5A1/CYP1A2/HSD17B12/HSD17B7/HSD17B6/STARD3NL/RDH13/ADH1C/CYP2S1/CYP19A1	20
BP	GO:1903038	negative regulation of leukocyte cell-cell adhesion	20/2306	129/18670	0.1681	0.3791	0.2916	ZC3H12A/ADORA2A/IRF1/CEBPB/TNFRSF14/PDCD1LG2/IDO1/BMP4/IL4R/SOCS1/LRRC32/KLF4/MAD1L1/DUSP3/HAVCR2/ASS1/HLA-G/SDC4/PDE5A/CBFB	20
BP	GO:0003197	endocardial cushion development	8/2306	44/18670	0.1693	0.3808	0.293	BMP2/BMP4/BMPR2/MSX2/TGFB2/SNAI2/ROBO1/ENG	8
BP	GO:0014003	oligodendrocyte development	8/2306	44/18670	0.1693	0.3808	0.293	ID2/CNTNAP1/ERCC2/LPAR1/HES5/GSN/EIF2B5/EIF2B4	8
BP	GO:0051489	regulation of filopodium assembly	8/2306	44/18670	0.1693	0.3808	0.293	FSCN1/FNBP1L/DPYSL3/ARF6/PRKCD/MYO10/RALA/CDC42	8
BP	GO:0060999	positive regulation of dendritic spine development	8/2306	44/18670	0.1693	0.3808	0.293	DBN1/CAPRIN1/EEF2K/LPAR1/ITPKA/BHLHB9/ARF1/ACTR2	8
BP	GO:0061756	leukocyte adhesion to vascular endothelial cell	8/2306	44/18670	0.1693	0.3808	0.293	ICAM1/VCAM1/ROCK1/ETS1/KLF4/ITGA4/TNF/GCNT1	8
BP	GO:0071622	regulation of granulocyte chemotaxis	8/2306	44/18670	0.1693	0.3808	0.293	CCL5/CSF1/JAM3/CMKLR1/SLIT2/THBS1/EDN1/AKIRIN1	8
BP	GO:1901028	regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	8/2306	44/18670	0.1693	0.3808	0.293	BID/PPP3CC/PMAIP1/TP63/ACAA2/YWHAH/TMEM14A/TFDP1	8
BP	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	14/2306	86/18670	0.1707	0.3827	0.2944	BID/FAS/MTCH1/FADD/PMAIP1/F2R/ROBO1/TRAF2/NKX3-1/TNF/TNFRSF10B/PPARG/FAM162A/ST20	14
BP	GO:0090559	regulation of membrane permeability	14/2306	86/18670	0.1707	0.3827	0.2944	BID/PPP3CC/HK2/PPIF/PMAIP1/BCL2L1/TP63/ACAA2/YWHAH/TMEM14A/TFDP1/STAT3/EYA2/PDCD6IP	14
BP	GO:0006814	sodium ion transport	32/2306	218/18670	0.1709	0.3827	0.2944	CNKSR3/GPD1L/KLHL3/SLC20A2/SLC38A2/SLC22A4/CAMK2D/PKD2/ANK3/SLC12A2/SLC3A2/COMMD3/SLC28A3/HECW2/HCN4/TPCN1/SHROOM2/ARF1/SLC38A4/YWHAH/ACTN4/SNTA1/SLC38A6/SCNN1A/PER1/ATP1A4/SIK1/OSR1/P2RX7/NEDD4/SLC38A1/SLC9A9	32
BP	GO:0060041	retina development in camera-type eye	22/2306	144/18670	0.1714	0.3827	0.2944	NDP/AHI1/PDGFRB/IRX5/RHOJ/BMPR2/SMARCD3/HIPK2/TGFB2/LRP5/IMPDH2/FJX1/TOPORS/CLN8/FZD4/PTPRM/ATP8A2/COL4A1/MAX/RDH13/MYH10/NPHP1	22
BP	GO:0021545	cranial nerve development	9/2306	51/18670	0.1717	0.3827	0.2944	ATP8B1/MAFB/SIX1/NAV2/LPAR1/SIX4/HES3/HOXD3/ADARB1	9
BP	GO:0030834	regulation of actin filament depolymerization	9/2306	51/18670	0.1717	0.3827	0.2944	LIMA1/RDX/DSTN/PLEKHH2/CAPZA2/EPS8/GSN/PDXP/TMOD2	9
BP	GO:0051452	intracellular pH reduction	9/2306	51/18670	0.1717	0.3827	0.2944	ATP6V1E2/ATP6V0B/RAB38/ATP6V0E2/PPT1/SLAMF8/DMXL1/ROGDI/ATP6V1E1	9
BP	GO:0030193	regulation of blood coagulation	13/2306	79/18670	0.1719	0.3827	0.2944	SERPINB2/C1QTNF1/PRKCA/PDPN/PLAU/THBS1/UBASH3B/EDN1/F2R/ABAT/PRKCD/SERPINE1/SERPINF2	13
BP	GO:0043536	positive regulation of blood vessel endothelial cell migration	13/2306	79/18670	0.1719	0.3827	0.2944	PTGS2/HSPB1/FGF2/PRKCA/VEGFA/PLK2/CD40/RHOJ/ETS1/THBS1/AMOTL1/SIRT1/ABL1	13
BP	GO:0035019	somatic stem cell population maintenance	12/2306	72/18670	0.1728	0.3827	0.2944	KIT/FGF2/LDB2/KLF4/LBH/ZFP36L2/YAP1/ASCL2/TP63/EPHA1/FGF10/STAT3	12
BP	GO:0051881	regulation of mitochondrial membrane potential	12/2306	72/18670	0.1728	0.3827	0.2944	BID/PID1/ADORA2A/ARL6IP5/PMAIP1/ABCD1/BCL2L1/ABL1/UBB/SLC25A33/P2RX7/SLC25A36	12
BP	GO:1903747	regulation of establishment of protein localization to mitochondrion	12/2306	72/18670	0.1728	0.3827	0.2944	BID/PPP3CC/PDCD5/DNAJA1/PMAIP1/ARIH2/RHOU/TP63/PARL/YWHAH/BAP1/TFDP1	12
BP	GO:0030837	negative regulation of actin filament polymerization	10/2306	58/18670	0.1729	0.3827	0.2944	SLIT2/MYADM/RDX/CAPZA2/PFN2/EPS8/GSN/PRKCD/MIR214/TMOD2	10
BP	GO:0046605	regulation of centrosome cycle	10/2306	58/18670	0.1729	0.3827	0.2944	CHMP1B/PLK2/CHMP4B/TRIM37/KAT2B/CEP250/CHMP5/ROCK2/MARK4/PDCD6IP	10
BP	GO:0061900	glial cell activation	10/2306	58/18670	0.1729	0.3827	0.2944	NAMPT/IL6/IL1B/IL33/ADORA2A/IFNGR1/BACE2/CCL3/TNF/TLR3	10
BP	GO:1903749	positive regulation of establishment of protein localization to mitochondrion	10/2306	58/18670	0.1729	0.3827	0.2944	BID/PPP3CC/PDCD5/PMAIP1/ARIH2/RHOU/TP63/YWHAH/BAP1/TFDP1	10
BP	GO:0050854	regulation of antigen receptor-mediated signaling pathway	11/2306	65/18670	0.1732	0.3827	0.2944	KCNN4/LPXN/GBP1/SLC39A10/CYLD/ADA/DUSP3/CACNA1F/PVRIG/BCL10/CBFB	11
BP	GO:0071806	protein transmembrane transport	11/2306	65/18670	0.1732	0.3827	0.2944	TRAM2/DNAJC19/SEC61G/DNAJC15/GRPEL1/GRPEL2/LONP2/PEX1/CHCHD4/PEX26/TIMM17B	11
BP	GO:0060048	cardiac muscle contraction	21/2306	137/18670	0.1741	0.3827	0.2944	ZC3H12A/GPD1L/GSTO1/CALM1/PDE4D/CAMK2D/ACTC1/SGCD/RGS2/HCN4/ADORA1/CALM2/ATP2A2/MIR1-2/SNTA1/PDE4B/KCND3/MYH6/NPPA/PDE5A/SRI	21
BP	GO:0072655	establishment of protein localization to mitochondrion	21/2306	137/18670	0.1741	0.3827	0.2944	BID/PPP3CC/PDCD5/DNAJA1/HK2/DNAJC19/PMAIP1/MIPEP/ARIH2/TOMM34/DNAJC15/RHOU/TP63/PARL/YWHAH/BAP1/GRPEL1/GRPEL2/CHCHD4/TFDP1/TIMM17B	21
BP	GO:0002902	regulation of B cell apoptotic process	4/2306	18/18670	0.1743	0.3827	0.2944	SLC39A10/ADA/FNIP1/BCL10	4
BP	GO:0006607	NLS-bearing protein import into nucleus	4/2306	18/18670	0.1743	0.3827	0.2944	KPNA3/KPNA2/NUP35/CBLB	4
BP	GO:0006743	ubiquinone metabolic process	4/2306	18/18670	0.1743	0.3827	0.2944	COQ10B/PDSS2/UBIAD1/COQ3	4
BP	GO:0009084	glutamine family amino acid biosynthetic process	4/2306	18/18670	0.1743	0.3827	0.2944	GLS/GLUD1/ASS1/CPS1	4
BP	GO:0009200	deoxyribonucleoside triphosphate metabolic process	4/2306	18/18670	0.1743	0.3827	0.2944	CMPK2/ADA/NUDT1/GUK1	4
BP	GO:0010766	negative regulation of sodium ion transport	4/2306	18/18670	0.1743	0.3827	0.2944	CAMK2D/HECW2/OSR1/NEDD4	4
BP	GO:0010878	cholesterol storage	4/2306	18/18670	0.1743	0.3827	0.2944	ABCA1/SOAT1/EHD1/PPARG	4
BP	GO:0030809	negative regulation of nucleotide biosynthetic process	4/2306	18/18670	0.1743	0.3827	0.2944	PID1/PPARGC1A/STAT3/SIRT6	4
BP	GO:0035089	establishment of apical/basal cell polarity	4/2306	18/18670	0.1743	0.3827	0.2944	FSCN1/WNT5A/PTK7/CDC42	4
BP	GO:0035994	response to muscle stretch	4/2306	18/18670	0.1743	0.3827	0.2944	NFKBIA/NFKB1/EDN1/NPPA	4
BP	GO:0039535	regulation of RIG-I signaling pathway	4/2306	18/18670	0.1743	0.3827	0.2944	BIRC3/BIRC2/DDX60/DHX58	4
BP	GO:0043011	myeloid dendritic cell differentiation	4/2306	18/18670	0.1743	0.3827	0.2944	CSF2/RELB/BATF3/UBD	4
BP	GO:0043555	regulation of translation in response to stress	4/2306	18/18670	0.1743	0.3827	0.2944	PPP1R15A/EIF2AK4/DNAJC3/SESN2	4
BP	GO:0045683	negative regulation of epidermis development	4/2306	18/18670	0.1743	0.3827	0.2944	MSX2/TP63/HES5/FERMT1	4
BP	GO:0048268	clathrin coat assembly	4/2306	18/18670	0.1743	0.3827	0.2944	EPS15/SGIP1/CLTC/PICALM	4
BP	GO:0050908	detection of light stimulus involved in visual perception	4/2306	18/18670	0.1743	0.3827	0.2944	REEP6/CEP250/CACNA1F/ATP8A2	4
BP	GO:0050962	detection of light stimulus involved in sensory perception	4/2306	18/18670	0.1743	0.3827	0.2944	REEP6/CEP250/CACNA1F/ATP8A2	4
BP	GO:0060192	negative regulation of lipase activity	4/2306	18/18670	0.1743	0.3827	0.2944	SORT1/ANXA8/RGS2/ABL1	4
BP	GO:0060749	mammary gland alveolus development	4/2306	18/18670	0.1743	0.3827	0.2944	ID2/VEGFA/CCND1/SOCS2	4
BP	GO:0060977	coronary vasculature morphogenesis	4/2306	18/18670	0.1743	0.3827	0.2944	VEGFA/PDGFRB/SGCD/MIR1-2	4
BP	GO:0061377	mammary gland lobule development	4/2306	18/18670	0.1743	0.3827	0.2944	ID2/VEGFA/CCND1/SOCS2	4
BP	GO:0072311	glomerular epithelial cell differentiation	4/2306	18/18670	0.1743	0.3827	0.2944	BASP1/BMP4/MYO1E/PODXL	4
BP	GO:0090026	positive regulation of monocyte chemotaxis	4/2306	18/18670	0.1743	0.3827	0.2944	CCL5/CXCL10/CCL1/SERPINE1	4
BP	GO:0090196	regulation of chemokine secretion	4/2306	18/18670	0.1743	0.3827	0.2944	IL33/IL4R/MBP/TNF	4
BP	GO:0097094	craniofacial suture morphogenesis	4/2306	18/18670	0.1743	0.3827	0.2944	RAB23/INSIG2/BMP4/MSX2	4
BP	GO:0098877	neurotransmitter receptor transport to plasma membrane	4/2306	18/18670	0.1743	0.3827	0.2944	STX3/SNAP47/VPS35/GRIPAP1	4
BP	GO:0098969	neurotransmitter receptor transport to postsynaptic membrane	4/2306	18/18670	0.1743	0.3827	0.2944	STX3/SNAP47/VPS35/GRIPAP1	4
BP	GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	4/2306	18/18670	0.1743	0.3827	0.2944	ZFP36/ZFP36L2/PABPC1/BTG2	4
BP	GO:1900372	negative regulation of purine nucleotide biosynthetic process	4/2306	18/18670	0.1743	0.3827	0.2944	PID1/PPARGC1A/STAT3/SIRT6	4
BP	GO:1903019	negative regulation of glycoprotein metabolic process	4/2306	18/18670	0.1743	0.3827	0.2944	BACE2/HBEGF/PTX3/ACOT8	4
BP	GO:2000047	regulation of cell-cell adhesion mediated by cadherin	4/2306	18/18670	0.1743	0.3827	0.2944	VEGFA/FLOT1/WNT5A/SERPINF2	4
BP	GO:2000193	positive regulation of fatty acid transport	4/2306	18/18670	0.1743	0.3827	0.2944	IL1B/FABP3/EDN1/P2RX7	4
BP	GO:0001963	synaptic transmission, dopaminergic	6/2306	31/18670	0.1765	0.3827	0.2944	PTGS2/ADORA2A/PNKD/FLOT1/CDK5/TOR1A	6
BP	GO:0010543	regulation of platelet activation	6/2306	31/18670	0.1765	0.3827	0.2944	C1QTNF1/PRKCA/PDPN/UBASH3B/ABAT/PRKCD	6
BP	GO:0030431	sleep	6/2306	31/18670	0.1765	0.3827	0.2944	CSF2/ADORA2A/OXTR/ADA/SRD5A1/ADORA1	6
BP	GO:0031338	regulation of vesicle fusion	6/2306	31/18670	0.1765	0.3827	0.2944	TBC1D4/RAB3A/SYT4/STXBP1/SYT1/ANKRD27	6
BP	GO:0042168	heme metabolic process	6/2306	31/18670	0.1765	0.3827	0.2944	SLC11A2/NFE2L1/HMOX2/ALAS1/SLC25A39/BDH2	6
BP	GO:0045648	positive regulation of erythrocyte differentiation	6/2306	31/18670	0.1765	0.3827	0.2944	ID2/ISG15/STAT1/ETS1/PRMT1/STAT3	6
BP	GO:0060292	long-term synaptic depression	6/2306	31/18670	0.1765	0.3827	0.2944	PLK2/ADORA1/KCNB1/ARF1/DGKI/STXBP1	6
BP	GO:0071880	adenylate cyclase-activating adrenergic receptor signaling pathway	6/2306	31/18670	0.1765	0.3827	0.2944	PDE4D/ADCY9/ARRDC3/MIR1-2/ADRB3/ADRA2A	6
BP	GO:0006638	neutral lipid metabolic process	20/2306	130/18670	0.1769	0.3827	0.2944	GK/LPIN1/PLCE1/C3/INSIG2/SLC22A4/FABP3/LIPG/CPT1A/DAGLA/SIRT1/RGN/DGKI/DAGLB/ABHD5/GPAM/CPS1/PTPN11/SIK1/TBL1XR1	20
BP	GO:0008033	tRNA processing	20/2306	130/18670	0.1769	0.3827	0.2944	TSEN15/ELP4/THADA/QTRT1/METTL6/SEPHS1/PUS10/LAGE3/NSUN3/USP14/PUS7/ALKBH8/LCMT2/LSM6/GRSF1/POLR3K/ADAT1/CDKAL1/TRMU/OSGEPL1	20
BP	GO:0002863	positive regulation of inflammatory response to antigenic stimulus	3/2306	12/18670	0.1774	0.3827	0.2944	C3/HLA-E/TNF	3
BP	GO:0002903	negative regulation of B cell apoptotic process	3/2306	12/18670	0.1774	0.3827	0.2944	SLC39A10/ADA/BCL10	3
BP	GO:0003334	keratinocyte development	3/2306	12/18670	0.1774	0.3827	0.2944	FLNB/KRT2/PALLD	3
BP	GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis	3/2306	12/18670	0.1774	0.3827	0.2944	LIF/STAT1/BMP4	3
BP	GO:0006527	arginine catabolic process	3/2306	12/18670	0.1774	0.3827	0.2944	DDAH1/FAH/DDAH2	3
BP	GO:0006563	L-serine metabolic process	3/2306	12/18670	0.1774	0.3827	0.2944	PSPH/PSAT1/PHGDH	3
BP	GO:0006568	tryptophan metabolic process	3/2306	12/18670	0.1774	0.3827	0.2944	KYNU/IDO1/AADAT	3
BP	GO:0006662	glycerol ether metabolic process	3/2306	12/18670	0.1774	0.3827	0.2944	TXN/FAR1/DHRS7B	3
BP	GO:0007077	mitotic nuclear envelope disassembly	3/2306	12/18670	0.1774	0.3827	0.2944	LPIN1/PRKCA/NEK6	3
BP	GO:0009111	vitamin catabolic process	3/2306	12/18670	0.1774	0.3827	0.2944	CBR3/CYP27B1/PDXP	3
BP	GO:0009265	2'-deoxyribonucleotide biosynthetic process	3/2306	12/18670	0.1774	0.3827	0.2944	CMPK2/CDADC1/GUK1	3
BP	GO:0010623	programmed cell death involved in cell development	3/2306	12/18670	0.1774	0.3827	0.2944	IL1B/IL1A/KIT	3
BP	GO:0014831	gastro-intestinal system smooth muscle contraction	3/2306	12/18670	0.1774	0.3827	0.2944	KIT/SULF2/SULF1	3
BP	GO:0016081	synaptic vesicle docking	3/2306	12/18670	0.1774	0.3827	0.2944	STX3/SNPH/PPFIA3	3
BP	GO:0016554	cytidine to uridine editing	3/2306	12/18670	0.1774	0.3827	0.2944	APOBEC3G/APOBEC3H/APOBEC3F	3
BP	GO:0019336	phenol-containing compound catabolic process	3/2306	12/18670	0.1774	0.3827	0.2944	DIO2/FAH/MOXD1	3
BP	GO:0019374	galactolipid metabolic process	3/2306	12/18670	0.1774	0.3827	0.2944	B4GALT3/UGT8/ALDH5A1	3
BP	GO:0021889	olfactory bulb interneuron differentiation	3/2306	12/18670	0.1774	0.3827	0.2944	SLIT2/ROBO1/WNT5A	3
BP	GO:0030002	cellular anion homeostasis	3/2306	12/18670	0.1774	0.3827	0.2944	XPR1/ENPP1/ABCC2	3
BP	GO:0030320	cellular monovalent inorganic anion homeostasis	3/2306	12/18670	0.1774	0.3827	0.2944	XPR1/ENPP1/ABCC2	3
BP	GO:0031392	regulation of prostaglandin biosynthetic process	3/2306	12/18670	0.1774	0.3827	0.2944	PTGS2/IL1B/SIRT1	3
BP	GO:0032429	regulation of phospholipase A2 activity	3/2306	12/18670	0.1774	0.3827	0.2944	ANXA8/PPT1/NMUR2	3
BP	GO:0034497	protein localization to phagophore assembly site	3/2306	12/18670	0.1774	0.3827	0.2944	WIPI1/WDR45/PACS2	3
BP	GO:0035721	intraciliary retrograde transport	3/2306	12/18670	0.1774	0.3827	0.2944	DYNC2LI1/DYNLL1/ICK	3
BP	GO:0035751	regulation of lysosomal lumen pH	3/2306	12/18670	0.1774	0.3827	0.2944	PPT1/TMEM175/TMEM165	3
BP	GO:0038003	opioid receptor signaling pathway	3/2306	12/18670	0.1774	0.3827	0.2944	PPP1R9B/SIGMAR1/OGFRL1	3
BP	GO:0042118	endothelial cell activation	3/2306	12/18670	0.1774	0.3827	0.2944	CXCL10/BMPER/HOXA9	3
BP	GO:0042308	negative regulation of protein import into nucleus	3/2306	12/18670	0.1774	0.3827	0.2944	RAB23/PKIG/FERMT1	3
BP	GO:0042416	dopamine biosynthetic process	3/2306	12/18670	0.1774	0.3827	0.2944	GCH1/TGFB2/VPS35	3
BP	GO:0043922	negative regulation by host of viral transcription	3/2306	12/18670	0.1774	0.3827	0.2944	CCL5/CCL3/ZNF639	3
BP	GO:0044650	adhesion of symbiont to host cell	3/2306	12/18670	0.1774	0.3827	0.2944	ICAM1/INHBB/GAS6	3
BP	GO:0045416	positive regulation of interleukin-8 biosynthetic process	3/2306	12/18670	0.1774	0.3827	0.2944	PRG3/TNF/BCL10	3
BP	GO:0046385	deoxyribose phosphate biosynthetic process	3/2306	12/18670	0.1774	0.3827	0.2944	CMPK2/CDADC1/GUK1	3
BP	GO:0046929	negative regulation of neurotransmitter secretion	3/2306	12/18670	0.1774	0.3827	0.2944	PNKD/SYT4/SLC30A1	3
BP	GO:0052803	imidazole-containing compound metabolic process	3/2306	12/18670	0.1774	0.3827	0.2944	MTHFD2L/HNMT/PRG3	3
BP	GO:0060019	radial glial cell differentiation	3/2306	12/18670	0.1774	0.3827	0.2944	HES5/FGF10/STAT3	3
BP	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	3/2306	12/18670	0.1774	0.3827	0.2944	ZFP36/PABPC1/BTG2	3
BP	GO:0060442	branching involved in prostate gland morphogenesis	3/2306	12/18670	0.1774	0.3827	0.2944	BMP4/RXRA/NKX3-1	3
BP	GO:0060788	ectodermal placode formation	3/2306	12/18670	0.1774	0.3827	0.2944	SIX1/SIX4/TBX3	3
BP	GO:0060900	embryonic camera-type eye formation	3/2306	12/18670	0.1774	0.3827	0.2944	ALDH1A3/WNT5A/ARID1A	3
BP	GO:0070586	cell-cell adhesion involved in gastrulation	3/2306	12/18670	0.1774	0.3827	0.2944	MYADM/KLF4/MBP	3
BP	GO:0071073	positive regulation of phospholipid biosynthetic process	3/2306	12/18670	0.1774	0.3827	0.2944	RAB38/FABP3/CAPN2	3
BP	GO:0071340	skeletal muscle acetylcholine-gated channel clustering	3/2306	12/18670	0.1774	0.3827	0.2944	DVL1/CRKL/RER1	3
BP	GO:0071697	ectodermal placode morphogenesis	3/2306	12/18670	0.1774	0.3827	0.2944	SIX1/SIX4/TBX3	3
BP	GO:0072393	microtubule anchoring at microtubule organizing center	3/2306	12/18670	0.1774	0.3827	0.2944	DCTN1/HOOK3/BICD2	3
BP	GO:0097340	inhibition of cysteine-type endopeptidase activity	3/2306	12/18670	0.1774	0.3827	0.2944	BIRC3/BIRC2/CAST	3
BP	GO:0097341	zymogen inhibition	3/2306	12/18670	0.1774	0.3827	0.2944	BIRC3/BIRC2/CAST	3
BP	GO:0099550	trans-synaptic signaling, modulating synaptic transmission	3/2306	12/18670	0.1774	0.3827	0.2944	F2R/SYT4/NPTN	3
BP	GO:1902337	regulation of apoptotic process involved in morphogenesis	3/2306	12/18670	0.1774	0.3827	0.2944	TNFRSF1B/TGFB2/VDR	3
BP	GO:1904590	negative regulation of protein import	3/2306	12/18670	0.1774	0.3827	0.2944	RAB23/PKIG/FERMT1	3
BP	GO:1904862	inhibitory synapse assembly	3/2306	12/18670	0.1774	0.3827	0.2944	SEMA4D/WNT5A/LHFPL4	3
BP	GO:1904953	Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation	3/2306	12/18670	0.1774	0.3827	0.2944	FZD1/CSNK1E/WNT5A	3
BP	GO:1905666	regulation of protein localization to endosome	3/2306	12/18670	0.1774	0.3827	0.2944	ANKRD13A/RDX/ROCK2	3
BP	GO:2000121	regulation of removal of superoxide radicals	3/2306	12/18670	0.1774	0.3827	0.2944	GCH1/RGN/TNF	3
BP	GO:2000341	regulation of chemokine (C-X-C motif) ligand 2 production	3/2306	12/18670	0.1774	0.3827	0.2944	KLF4/MBP/TNF	3
BP	GO:0007631	feeding behavior	16/2306	101/18670	0.1776	0.3829	0.2946	ADORA2A/GLS/FYN/SGIP1/OXTR/EIF2AK4/ADM2/CPT1A/MMP17/GDF15/MRAP2/ATP8A2/IAPP/NMUR2/STAT3/RMI1	16
BP	GO:1990542	mitochondrial transmembrane transport	16/2306	101/18670	0.1776	0.3829	0.2946	SLC25A28/ACACB/DNAJC19/SLC25A37/CPT1A/ACACA/DNAJC15/SLC25A20/GRPEL1/GRPEL2/PRKAB2/CHCHD4/SLC25A33/SLC25A36/MID1IP1/TIMM17B	16
BP	GO:0006352	DNA-templated transcription, initiation	36/2306	249/18670	0.1777	0.383	0.2947	PPARGC1A/WWTR1/MED10/RXRA/CCND1/BCLAF1/E2F2/SMARCA5/DR1/ERCC2/KAT2B/CAND1/MITF/THRA/YAP1/VDR/TAF13/PPM1D/CDK8/SUB1/MED8/TAF7L/GTF2H5/TAF6L/PPARG/CDKN1A/MED20/NPPA/MNAT1/POLR1C/GTF3C4/GTF2F2/CDK7/ZNF451/NCOA6/CBFB	36
BP	GO:0006605	protein targeting	60/2306	432/18670	0.1809	0.3897	0.2998	BID/ACOX2/TRAM2/PDCD5/PAK1/DNAJC19/FYN/SEC61G/CHMP4B/ANK3/IDH1/RPS3A/NUDT7/GNPTAB/CROT/MICALL1/AKAP12/VPS37D/GCC2/MIPEP/SDCBP/ARIH2/VPS37C/TOMM34/RPL7/AMACR/RPL22/RTP4/DNAJC15/RHOU/CDK5/ADORA1/KCNB1/RPL37A/DECR2/PARL/SSR2/BAP1/SSR1/GRPEL1/GRPEL2/GDI1/LTBP2/RPL15/LONP2/PEX1/ACOT8/CHCHD4/PECR/UBB/SCP2/VAMP7/ZDHHC18/M6PR/PEX26/RASSF9/USP9X/NEDD4/RPS18/TIMM17B	60
BP	GO:0021915	neural tube development	24/2306	160/18670	0.1819	0.3911	0.3009	BMP4/FZD1/NUP133/PKD2/SHROOM3/STK4/FZD2/TGFB2/WNT5A/HES5/PTK7/HES3/GPR161/SALL2/PHGDH/ARID1A/SDC4/ABL1/BCL10/RALA/MIB1/DVL1/DVL2/SSBP3	24
BP	GO:0006040	amino sugar metabolic process	7/2306	38/18670	0.1821	0.3911	0.3009	GFPT2/ST3GAL1/NAGK/CHST7/CSGALNACT1/PGM3/MGAT1	7
BP	GO:0006656	phosphatidylcholine biosynthetic process	7/2306	38/18670	0.1821	0.3911	0.3009	LPIN1/RAB38/FABP3/ABHD3/CHKB/CAPN2/STARD7	7
BP	GO:0010831	positive regulation of myotube differentiation	7/2306	38/18670	0.1821	0.3911	0.3009	IL4R/CXCL9/FLOT1/EHD1/GDF15/MIR1-2/CAPN2	7
BP	GO:0045022	early endosome to late endosome transport	7/2306	38/18670	0.1821	0.3911	0.3009	DAB2/RDX/HOOK3/WDR91/AKTIP/ANKRD27/SNX3	7
BP	GO:0050716	positive regulation of interleukin-1 secretion	7/2306	38/18670	0.1821	0.3911	0.3009	RIPK2/PANX1/PANX2/CCL3/GSDMD/WNT5A/P2RX7	7
BP	GO:0060045	positive regulation of cardiac muscle cell proliferation	7/2306	38/18670	0.1821	0.3911	0.3009	FGF2/PIM1/GATA6/YAP1/MEF2C/MIR19B2/MIR199A2	7
BP	GO:1902742	apoptotic process involved in development	7/2306	38/18670	0.1821	0.3911	0.3009	TNFRSF1B/PPP2R1B/SLIT2/CRYAB/TGFB2/VDR/MIR19B2	7
BP	GO:1904706	negative regulation of vascular smooth muscle cell proliferation	7/2306	38/18670	0.1821	0.3911	0.3009	SOD2/MEF2C/MIR137/MIR1-2/MIR214/PPARG/CDKN1A	7
BP	GO:0006661	phosphatidylinositol biosynthetic process	18/2306	116/18670	0.1825	0.3919	0.3015	FGF2/PIK3CD/PIGV/PIK3R2/PTPN13/PIK3R3/RAB4A/PLEKHA3/ARF1/ARF3/MPPE1/PIGK/PIGS/PIP4K2A/PI4K2B/SH3YL1/SBF1/PLEKHA4	18
BP	GO:0030048	actin filament-based movement	21/2306	138/18670	0.1829	0.3926	0.3021	PDPN/FNBP1L/GPD1L/ROCK1/PDE4D/CAMK2D/ACTC1/MYO1E/SGCD/TPM4/ADORA1/ACTN4/MIR1-2/SNTA1/PDE4B/KCND3/MYH6/MYH9/MYH10/SRI/WASF2	21
BP	GO:0002088	lens development in camera-type eye	13/2306	80/18670	0.1835	0.3937	0.3029	MEIS1/SLC7A11/BMP4/SIX5/BCAR3/CRYAB/CRYGS/HIPK2/WNT5B/WNT5A/SHROOM2/CDKN1C/GATA3	13
BP	GO:1900046	regulation of hemostasis	13/2306	80/18670	0.1835	0.3937	0.3029	SERPINB2/C1QTNF1/PRKCA/PDPN/PLAU/THBS1/UBASH3B/EDN1/F2R/ABAT/PRKCD/SERPINE1/SERPINF2	13
BP	GO:0033555	multicellular organismal response to stress	12/2306	73/18670	0.185	0.3958	0.3045	IDO1/NPAS2/GCH1/THBS1/LRP11/MEF2C/P2RX3/CACNA1B/PPP3CA/VDAC1/NMUR2/CAPN2	12
BP	GO:0045685	regulation of glial cell differentiation	12/2306	73/18670	0.185	0.3958	0.3045	BMP2/IL6/GPR37L1/LIF/ID2/TNFRSF1B/IL6ST/CLCF1/DAAM2/HES5/DUSP10/PPARG	12
BP	GO:0046128	purine ribonucleoside metabolic process	12/2306	73/18670	0.185	0.3958	0.3045	RAB23/AMPD3/NUDT18/ADA/NT5C2/NME5/IMPDH2/GAMT/GUK1/MTAP/PRTFDC1/GNMT	12
BP	GO:0002820	negative regulation of adaptive immune response	8/2306	45/18670	0.1851	0.3958	0.3045	ZC3H12A/IL33/IL7R/TNFRSF14/IL4R/HLA-F/HAVCR2/HLA-G	8
BP	GO:0002833	positive regulation of response to biotic stimulus	8/2306	45/18670	0.1851	0.3958	0.3045	RIPK2/PRKCA/DDX60/IL12A/CYBA/DHX58/OPTN/HAVCR2	8
BP	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	8/2306	45/18670	0.1851	0.3958	0.3045	CD44/DYRK2/HIPK2/BCL3/SIRT1/TP63/TOPORS/CDKN1A	8
BP	GO:0090278	negative regulation of peptide hormone secretion	8/2306	45/18670	0.1851	0.3958	0.3045	IRS1/HADH/INHBB/KCNB1/SYTL4/PPP3CA/PTPN11/ADRA2A	8
BP	GO:1900271	regulation of long-term synaptic potentiation	8/2306	45/18670	0.1851	0.3958	0.3045	ADORA2A/SQSTM1/EIF2AK4/ADORA1/STAU1/NPTN/ABL1/YTHDF1	8
BP	GO:0034250	positive regulation of cellular amide metabolic process	23/2306	153/18670	0.1851	0.3958	0.3045	CCL5/IL6/IFNGR1/PPP1R15A/RXRA/THBS1/EIF2AK4/DNAJC3/ITGA2/MPV17L2/BCL3/PABPC1/DHX29/EIF3E/TNF/EIF2B5/PRKCD/FASTKD3/ROCK2/FXR2/NSMAF/YTHDF1/PICALM	23
BP	GO:0062013	positive regulation of small molecule metabolic process	23/2306	153/18670	0.1851	0.3958	0.3045	PTGS2/PID1/IL1B/NFKB1/PPARGC1A/FOXO1/ELOVL5/RDH10/IRS1/DYRK2/PMAIP1/CPT1A/KAT2B/HAS2/ABCD1/SIRT1/RGN/TNF/PPARG/IGF1/STAT3/P2RX7/MID1IP1	23
BP	GO:1902807	negative regulation of cell cycle G1/S phase transition	20/2306	131/18670	0.186	0.3975	0.3058	CCL2/CDK6/FHL1/PLK2/RPA2/PKD2/CCND1/KLF4/PRMT1/GJC2/CARM1/CDKN2C/BTG2/MIR137/ARID3A/CNOT8/CDK2AP2/CTDSP2/CDKN1A/TFDP1	20
BP	GO:1901880	negative regulation of protein depolymerization	11/2306	66/18670	0.1861	0.3976	0.3059	MID1/LIMA1/RDX/PLEKHH2/CAPZA2/EPS8/GSN/TMOD2/TAOK1/MID1IP1/CAMSAP1	11
BP	GO:0051438	regulation of ubiquitin-protein transferase activity	9/2306	52/18670	0.1864	0.3977	0.306	BAG2/TRIB3/CDC14B/ARRDC4/ARRDC3/DCUN1D4/TOPORS/ABL1/UBE2S	9
BP	GO:0072132	mesenchyme morphogenesis	9/2306	52/18670	0.1864	0.3977	0.306	BMP2/MSX2/ACTC1/TGFB2/SNAI2/ROBO1/WNT5A/ENG/OSR1	9
BP	GO:2000649	regulation of sodium ion transmembrane transporter activity	9/2306	52/18670	0.1864	0.3977	0.306	CNKSR3/GPD1L/CAMK2D/ANK3/HECW2/YWHAH/ACTN4/OSR1/NEDD4	9
BP	GO:2000772	regulation of cellular senescence	9/2306	52/18670	0.1864	0.3977	0.306	NAMPT/CDK6/PLK2/ARNTL/NUAK1/SIRT1/NEK6/HLA-G/ABL1	9
BP	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	49/2306	349/18670	0.1866	0.3979	0.3062	BMP2/CITED2/DAB2/BMP4/WWTR1/AFP/GREM2/FZD1/LRRC32/ITGB5/BMPR2/THBS1/MSX2/BMPER/PXN/INHBB/SDCBP/HIPK2/TGFB2/AKAP3/GDF5/SIRT1/WNT5A/SULF1/GDF15/HES5/CDKN1C/FBN1/DDX5/APPL2/FERMT2/SUB1/FKBP1A/LTBP2/FST/ZYX/ABL1/CTDSPL2/COL1A2/UBB/MYH6/ENG/FGF10/FERMT1/GDF6/USP9X/ZNF451/ATOH8/SMAD9	49
BP	GO:0001836	release of cytochrome c from mitochondria	10/2306	59/18670	0.1867	0.3979	0.3062	SOD2/BID/PDCD5/PPIF/LMNA/PMAIP1/MMP9/BCL2L1/FAM162A/IGF1	10
BP	GO:0051250	negative regulation of lymphocyte activation	22/2306	146/18670	0.1885	0.4	0.3077	ZC3H12A/TNFAIP3/ID2/ADORA2A/IRF1/CEBPB/TNFRSF14/PDCD1LG2/IDO1/BMP4/IL4R/SOCS1/HLA-F/LRRC32/MAD1L1/DUSP3/AXL/HAVCR2/HLA-G/SDC4/PDE5A/CBFB	22
BP	GO:0001945	lymph vessel development	5/2306	25/18670	0.1886	0.4	0.3077	PDPN/VEGFA/NR2F2/BMPR2/LGALS8	5
BP	GO:0002053	positive regulation of mesenchymal cell proliferation	5/2306	25/18670	0.1886	0.4	0.3077	SIX1/STAT1/VEGFA/LRP5/WNT5A	5
BP	GO:0003071	renal system process involved in regulation of systemic arterial blood pressure	5/2306	25/18670	0.1886	0.4	0.3077	CYBA/F2R/ADORA1/GAS6/SERPINF2	5
BP	GO:0003309	type B pancreatic cell differentiation	5/2306	25/18670	0.1886	0.4	0.3077	CDK6/BMP4/ARNTL/GATA6/WNT5A	5
BP	GO:0006688	glycosphingolipid biosynthetic process	5/2306	25/18670	0.1886	0.4	0.3077	ST8SIA1/B4GALT3/UGCG/A4GALT/UGT8	5
BP	GO:0032509	endosome transport via multivesicular body sorting pathway	5/2306	25/18670	0.1886	0.4	0.3077	CHMP1B/SORT1/VPS37D/VPS36/VPS37C	5
BP	GO:0034035	purine ribonucleoside bisphosphate metabolic process	5/2306	25/18670	0.1886	0.4	0.3077	TPST1/ENPP1/SULT1C4/PAPSS1/SULT2B1	5
BP	GO:0044247	cellular polysaccharide catabolic process	5/2306	25/18670	0.1886	0.4	0.3077	PYGL/CALM1/PGM2L1/PHKB/PHKA2	5
BP	GO:0045662	negative regulation of myoblast differentiation	5/2306	25/18670	0.1886	0.4	0.3077	CXCL10/BMP4/TNF/ID3/TBX3	5
BP	GO:0050901	leukocyte tethering or rolling	5/2306	25/18670	0.1886	0.4	0.3077	VCAM1/ROCK1/ITGA4/TNF/GCNT1	5
BP	GO:0051894	positive regulation of focal adhesion assembly	5/2306	25/18670	0.1886	0.4	0.3077	VEGFA/ROCK1/COL16A1/SDC4/ABL1	5
BP	GO:0060561	apoptotic process involved in morphogenesis	5/2306	25/18670	0.1886	0.4	0.3077	TNFRSF1B/PPP2R1B/CRYAB/TGFB2/VDR	5
BP	GO:0072012	glomerulus vasculature development	5/2306	25/18670	0.1886	0.4	0.3077	CFLAR/BMP4/PDGFRB/PDGFD/OSR1	5
BP	GO:2000482	regulation of interleukin-8 secretion	5/2306	25/18670	0.1886	0.4	0.3077	CD58/F2R/WNT5A/ANXA4/MAPKBP1	5
BP	GO:0051480	regulation of cytosolic calcium ion concentration	50/2306	357/18670	0.1887	0.4	0.3078	BDKRB1/S1PR3/CXCL10/BDKRB2/FGF2/C1QTNF1/PLCE1/GSTO1/PTGFR/CMKLR1/FYN/CALM1/PDE4D/CAMK2D/PKD2/CXCL11/CCL3/CYBA/UBASH3B/OXTR/EDN1/PTGER2/CXCL9/TRPC1/F2R/CCL1/LPAR1/TMEM64/GNA13/ITPR2/CDK5/WNT5A/ADORA1/TPCN1/P2RX3/CALM2/MIR1-2/DLG4/FKBP1A/IAPP/DIAPH1/NPTN/ABL1/MCOLN1/NMUR2/MIR199A2/CCR10/SRI/P2RX7/CASQ1	50
BP	GO:0019751	polyol metabolic process	19/2306	124/18670	0.1892	0.4009	0.3084	AKR1B1/GK/PLCD3/FGF2/PLCE1/PLCD1/MYOF/CALM1/GCH1/CYP27B1/NUDT11/IMPA2/PLCB4/ITPKA/COQ3/INPP5B/IP6K3/INPP1/PTS	19
BP	GO:0046883	regulation of hormone secretion	38/2306	266/18670	0.19	0.4026	0.3098	CCL5/IL1B/LIF/ENSA/ADORA2A/C1QTNF1/PRKCA/SLC2A1/GIP/MYB/IRS1/SNX4/GLUD1/EDN1/HADH/TCF7L2/INHBB/ARNTL/CPT1A/LRP5/ITPR2/ADORA1/KCNB1/NKX3-1/ABAT/TNF/SYTL4/DYNLL1/BRSK2/PPP3CA/RAB11FIP1/VAMP7/PTPN11/NPPA/ARL2BP/SRI/CYP19A1/ADRA2A	38
BP	GO:0018393	internal peptidyl-lysine acetylation	24/2306	161/18670	0.1901	0.4027	0.3098	IL1B/LIF/BRPF3/PPARGC1A/AUTS2/SET/DR1/KAT2B/SNAI2/MORF4L2/RPS6KA4/YEATS2/SIRT1/MSL1/GATA3/IWS1/SETD5/TAF6L/PER1/GTF3C4/MSL3/ZNF451/TADA3/PHF10	24
BP	GO:0042100	B cell proliferation	15/2306	95/18670	0.1906	0.4035	0.3105	CD70/IL7R/AHR/TNFSF13B/CD40/SLC39A10/ADA/CLCF1/MEF2C/CD79A/PRKCD/ABL1/CDKN1A/TICAM1/SASH3	15
BP	GO:0050796	regulation of insulin secretion	26/2306	176/18670	0.1912	0.4046	0.3113	CCL5/IL1B/ENSA/PRKCA/SLC2A1/GIP/IRS1/GLUD1/HADH/TCF7L2/INHBB/ARNTL/CPT1A/LRP5/ITPR2/KCNB1/ABAT/TNF/SYTL4/DYNLL1/BRSK2/PPP3CA/PTPN11/ARL2BP/SRI/ADRA2A	26
BP	GO:0001935	endothelial cell proliferation	28/2306	191/18670	0.1918	0.4057	0.3121	BMP2/CCL2/ERN1/FGF2/PRKCA/STAT1/VEGFA/BMP4/NR2F2/BMPR2/ITGA4/CYBA/THBS1/BMPER/MEF2C/NOX5/SIRT1/WNT5A/SULF1/TNF/PGF/SPARC/PTPRM/PPARG/AGGF1/STAT3/SIRT6/ATOH8	28
BP	GO:0016571	histone methylation	21/2306	139/18670	0.1919	0.4058	0.3122	JARID2/AUTS2/RNF20/MYB/LMNA/PRMT1/TET1/SMYD3/CARM1/SETDB2/SIRT1/PRMT3/TET3/RBBP5/GATA3/PRDM13/IWS1/SETMAR/SETD5/RLF/ARID4A	21
BP	GO:0010822	positive regulation of mitochondrion organization	18/2306	117/18670	0.1923	0.4065	0.3127	BID/PPP3CC/PPARGC1A/PDCD5/HK2/PPIF/PMAIP1/ARIH2/MMP9/RHOU/OPTN/VPS35/CAMKK2/TP63/YWHAH/BAP1/TFDP1/FAM162A	18
BP	GO:0031398	positive regulation of protein ubiquitination	18/2306	117/18670	0.1923	0.4065	0.3127	BIRC3/RIPK2/BIRC2/RNF20/NDFIP1/TRIB3/CDC14B/ARRDC4/ARRDC3/DCUN1D4/TOPORS/FKBP1A/BCL10/UBB/NDFIP2/TICAM1/MYCBP2/UBE2S	18
BP	GO:0046879	hormone secretion	44/2306	312/18670	0.193	0.4077	0.3137	CCL5/IL6/IL1B/LIF/ENSA/ADORA2A/C1QTNF1/PRKCA/SLC2A1/GIP/MYB/IRS1/SNX4/GLUD1/EDN1/HADH/TCF7L2/INHBB/ARNTL/CPT1A/RAB11FIP2/LRP5/ITPR2/ADORA1/KCNB1/NKX3-1/ABAT/TNF/CAMK2G/SYTL4/DYNLL1/BRSK2/FZD4/GATA3/PPP3CA/RAB11FIP1/VAMP7/PTPN11/NPPA/ARL2BP/SRI/CYP19A1/ADRA2A/TBX3	44
BP	GO:1901863	positive regulation of muscle tissue development	14/2306	88/18670	0.1931	0.4079	0.3139	PPARGC1A/FGF2/BMP4/PIM1/EDN1/ARNTL/GATA6/YAP1/FLOT1/MEF2C/MIR19B2/MIR1-2/MIR199A2/IGF1	14
BP	GO:0002429	immune response-activating cell surface receptor signaling pathway	65/2306	473/18670	0.1935	0.4086	0.3144	NFKBIZ/ZC3H12A/PSME2/RELB/RIPK2/KCNN4/NFKB1/PSMA6/PSMB10/PSMB8/PIK3CD/ARPC1A/PSMB7/LPXN/PSME1/PLSCR1/BTN3A1/PAK1/PSMB9/ACTR3/CMKLR1/FYN/PDE4D/PSMA3/GBP1/SLC39A10/BTN2A1/PIK3R2/CYLD/ADA/BTN3A3/DUSP3/PSMA1/MEF2C/PSMB2/ARPC2/PSMB3/MICB/ACTB/CACNA1F/APPL2/EIF2B5/EIF2B4/CD79A/PVRIG/GATA3/PRKCD/PSMA8/HLA-DQB1/ABL1/RBCK1/BCL10/PDE4B/MYO10/MUC15/MUC17/ACTR2/PSME4/CDC42/PSMB5/ACTG1/CRKL/PSMF1/WASF2/CBFB	65
BP	GO:0016101	diterpenoid metabolic process	17/2306	110/18670	0.1955	0.4121	0.3171	AKR1B1/ALDH1A3/CYP27C1/GPC4/RDH10/RDH8/HSPG2/DHRS3/SRD5A1/ADH5/SDC2/CYP1A2/SDC4/PECR/RDH13/ADH1C/CYP2S1	17
BP	GO:0098739	import across plasma membrane	17/2306	110/18670	0.1955	0.4121	0.3171	SLC39A14/SLC7A2/SLC7A11/FYN/ARL6IP5/SLC39A10/SLC12A2/SLC3A2/SLC39A8/RGS2/HCN4/RGS4/SLC30A1/CLN8/ATP1A4/SLC19A1/SLC9A9	17
BP	GO:0007045	cell-substrate adherens junction assembly	13/2306	81/18670	0.1955	0.4121	0.3171	CORO1C/VEGFA/ROCK1/THBS1/TRIP6/ITGA2/DUSP3/PHLDB2/FERMT2/COL16A1/SDC4/ABL1/ROCK2	13
BP	GO:0016126	sterol biosynthetic process	13/2306	81/18670	0.1955	0.4121	0.3171	CH25H/INSIG2/ACACB/SCD/CYB5R2/TM7SF2/ACAT2/ACACA/NPC1L1/ACAA2/HSD17B7/GPAM/IDI1	13
BP	GO:0048041	focal adhesion assembly	13/2306	81/18670	0.1955	0.4121	0.3171	CORO1C/VEGFA/ROCK1/THBS1/TRIP6/ITGA2/DUSP3/PHLDB2/FERMT2/COL16A1/SDC4/ABL1/ROCK2	13
BP	GO:0008210	estrogen metabolic process	6/2306	32/18670	0.1961	0.4127	0.3176	RDH8/DHRS11/CYP1A2/HSD17B12/HSD17B7/CYP19A1	6
BP	GO:0032228	regulation of synaptic transmission, GABAergic	6/2306	32/18670	0.1961	0.4127	0.3176	ADORA2A/OXTR/NISCH/ADORA1/CNR2/STXBP1	6
BP	GO:0039694	viral RNA genome replication	6/2306	32/18670	0.1961	0.4127	0.3176	FBXL2/APOBEC3G/APOBEC3H/APOBEC3F/ROCK2/CDC42	6
BP	GO:2000778	positive regulation of interleukin-6 secretion	6/2306	32/18670	0.1961	0.4127	0.3176	IL1B/IFIH1/DDX58/MBP/F2R/TNF	6
BP	GO:0010212	response to ionizing radiation	22/2306	147/18670	0.1974	0.4153	0.3195	ICAM1/NAMPT/VCAM1/CXCL10/CCL7/KRT14/CCND1/NET1/CYBA/CRYAB/RHOB/SNAI2/YAP1/POLB/SIRT1/BCL2L1/XRCC4/GATA3/GTF2H5/NUCKS1/CDKN1A/UIMC1	22
BP	GO:0050710	negative regulation of cytokine secretion	12/2306	74/18670	0.1977	0.4155	0.3197	ZC3H12A/TNFAIP3/LRRC32/GBP1/SRGN/ANXA4/TNF/SERPINB1/LGR4/GAS6/PYDC2/MAPKBP1	12
BP	GO:0070373	negative regulation of ERK1 and ERK2 cascade	12/2306	74/18670	0.1977	0.4155	0.3197	TNIP1/LIF/CNKSR3/DUSP6/KLF4/GBP1/SIRPA/SPRY1/ERRFI1/DUSP3/ABL1/DUSP10	12
BP	GO:1901616	organic hydroxy compound catabolic process	12/2306	74/18670	0.1977	0.4155	0.3197	GK/DIO2/FAH/CYP27B1/IMPA2/MOXD1/SULT1C4/HSD3B7/INPP5B/LDHD/PDXP/INPP1	12
BP	GO:0018958	phenol-containing compound metabolic process	16/2306	103/18670	0.1987	0.4163	0.3203	AKR1B1/DIO2/EPAS1/SLC7A11/PNKD/GCH1/FAH/SRD5A1/MC1R/TRPC1/TGFB2/MOXD1/WNT5A/VPS35/ABAT/GATA3	16
BP	GO:0048259	regulation of receptor-mediated endocytosis	16/2306	103/18670	0.1987	0.4163	0.3203	AHI1/DAB2/C3/VEGFA/ANKRD13A/MKLN1/SGIP1/PPT1/SDCBP/FLOT1/ARF6/ARF1/DLG4/SERPINE1/MIR199A2/PICALM	16
BP	GO:1905269	positive regulation of chromatin organization	16/2306	103/18670	0.1987	0.4163	0.3203	IL1B/LIF/PPARGC1A/JARID2/AUTS2/VEGFA/RNF20/MYB/LMNA/TET1/SNAI2/RPS6KA4/SIRT1/AKAP8/GATA3/SIRT6	16
BP	GO:0007257	activation of JUN kinase activity	7/2306	39/18670	0.1999	0.4163	0.3203	RIPK2/ERN1/DAXX/WNT5A/MAP3K2/MLKL/TAOK1	7
BP	GO:0009072	aromatic amino acid family metabolic process	7/2306	39/18670	0.1999	0.4163	0.3203	KYNU/MTHFD2L/IDO1/IL4I1/FAH/HNMT/AADAT	7
BP	GO:0010661	positive regulation of muscle cell apoptotic process	7/2306	39/18670	0.1999	0.4163	0.3203	SOD2/IL12A/CAMK2D/STK4/MIR1-2/PPARG/CAPN2	7
BP	GO:0031062	positive regulation of histone methylation	7/2306	39/18670	0.1999	0.4163	0.3203	JARID2/AUTS2/RNF20/MYB/LMNA/TET1/SIRT1	7
BP	GO:0032692	negative regulation of interleukin-1 production	7/2306	39/18670	0.1999	0.4163	0.3203	ZC3H12A/TNFAIP3/ERRFI1/SERPINB1/GAS6/PYDC2/IGF1	7
BP	GO:0038179	neurotrophin signaling pathway	7/2306	39/18670	0.1999	0.4163	0.3203	ZFYVE27/SORT1/DOK5/KIDINS220/SPRY1/PTPN11/TMEM108	7
BP	GO:0045911	positive regulation of DNA recombination	7/2306	39/18670	0.1999	0.4163	0.3203	CD40/EXOSC6/ERCC2/CLCF1/STAT6/MMS19/ACTR2	7
BP	GO:0060969	negative regulation of gene silencing	7/2306	39/18670	0.1999	0.4163	0.3203	ZC3H12A/ADAR/TET1/PPP3CA/NCOR2/ASF1A/PPARG	7
BP	GO:0001710	mesodermal cell fate commitment	4/2306	19/18670	0.2006	0.4163	0.3203	BMP4/KLF4/HOXA11/EYA2	4
BP	GO:0002076	osteoblast development	4/2306	19/18670	0.2006	0.4163	0.3203	MSX2/PTHLH/LRP5/BGLAP	4
BP	GO:0002689	negative regulation of leukocyte chemotaxis	4/2306	19/18670	0.2006	0.4163	0.3203	CCL2/SLIT2/SLAMF8/CYP19A1	4
BP	GO:0003159	morphogenesis of an endothelium	4/2306	19/18670	0.2006	0.4163	0.3203	CXCL10/BMP4/RHOB/STARD13	4
BP	GO:0010544	negative regulation of platelet activation	4/2306	19/18670	0.2006	0.4163	0.3203	C1QTNF1/UBASH3B/ABAT/PRKCD	4
BP	GO:0016082	synaptic vesicle priming	4/2306	19/18670	0.2006	0.4163	0.3203	SNAP47/RAB3A/STXBP1/NAPB	4
BP	GO:0032011	ARF protein signal transduction	4/2306	19/18670	0.2006	0.4163	0.3203	CYTH3/PSD4/IQSEC1/MAPRE2	4
BP	GO:0032012	regulation of ARF protein signal transduction	4/2306	19/18670	0.2006	0.4163	0.3203	CYTH3/PSD4/IQSEC1/MAPRE2	4
BP	GO:0032026	response to magnesium ion	4/2306	19/18670	0.2006	0.4163	0.3203	CCND1/ANK3/THBS1/TNFRSF11B	4
BP	GO:0032288	myelin assembly	4/2306	19/18670	0.2006	0.4163	0.3203	CNTNAP1/EPB41L3/ERCC2/UGT8	4
BP	GO:0035493	SNARE complex assembly	4/2306	19/18670	0.2006	0.4163	0.3203	VAMP4/STXBP1/VAMP7/ANKRD27	4
BP	GO:0036303	lymph vessel morphogenesis	4/2306	19/18670	0.2006	0.4163	0.3203	PDPN/VEGFA/BMPR2/LGALS8	4
BP	GO:0042693	muscle cell fate commitment	4/2306	19/18670	0.2006	0.4163	0.3203	MEF2C/MIR19B2/FGF10/TBX3	4
BP	GO:0046653	tetrahydrofolate metabolic process	4/2306	19/18670	0.2006	0.4163	0.3203	MTHFD2L/GCH1/MTHFD2/ALDH1L2	4
BP	GO:0048486	parasympathetic nervous system development	4/2306	19/18670	0.2006	0.4163	0.3203	SIX1/NAV2/HES3/ADARB1	4
BP	GO:0061154	endothelial tube morphogenesis	4/2306	19/18670	0.2006	0.4163	0.3203	CXCL10/BMP4/RHOB/STARD13	4
BP	GO:0070989	oxidative demethylation	4/2306	19/18670	0.2006	0.4163	0.3203	FTO/TET1/CYP1A2/TET3	4
BP	GO:0071071	regulation of phospholipid biosynthetic process	4/2306	19/18670	0.2006	0.4163	0.3203	RAB38/FABP3/IDH1/CAPN2	4
BP	GO:0072087	renal vesicle development	4/2306	19/18670	0.2006	0.4163	0.3203	LIF/STAT1/BMP4/OSR1	4
BP	GO:0090201	negative regulation of release of cytochrome c from mitochondria	4/2306	19/18670	0.2006	0.4163	0.3203	PPIF/LMNA/BCL2L1/IGF1	4
BP	GO:1902074	response to salt	4/2306	19/18670	0.2006	0.4163	0.3203	ZC3H12A/DAXX/EDN1/MAPK13	4
BP	GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	4/2306	19/18670	0.2006	0.4163	0.3203	SOD2/HSPB1/NME5/SIRT1	4
BP	GO:1903540	establishment of protein localization to postsynaptic membrane	4/2306	19/18670	0.2006	0.4163	0.3203	STX3/SNAP47/VPS35/GRIPAP1	4
BP	GO:1904683	regulation of metalloendopeptidase activity	4/2306	19/18670	0.2006	0.4163	0.3203	RECK/MBP/STAT3/PICALM	4
BP	GO:1990182	exosomal secretion	4/2306	19/18670	0.2006	0.4163	0.3203	SDCBP/SDC4/ATP13A2/PDCD6IP	4
BP	GO:2000010	positive regulation of protein localization to cell surface	4/2306	19/18670	0.2006	0.4163	0.3203	GPD1L/STX3/MAP1A/TNF	4
BP	GO:0046324	regulation of glucose import	10/2306	60/18670	0.2009	0.4163	0.3203	PID1/HK2/IRS1/ENPP1/ADIPOR2/TNF/APPL2/PTPN11/IGF1/SIRT6	10
BP	GO:0051893	regulation of focal adhesion assembly	10/2306	60/18670	0.2009	0.4163	0.3203	CORO1C/VEGFA/ROCK1/THBS1/DUSP3/PHLDB2/COL16A1/SDC4/ABL1/ROCK2	10
BP	GO:0090109	regulation of cell-substrate junction assembly	10/2306	60/18670	0.2009	0.4163	0.3203	CORO1C/VEGFA/ROCK1/THBS1/DUSP3/PHLDB2/COL16A1/SDC4/ABL1/ROCK2	10
BP	GO:0090342	regulation of cell aging	10/2306	60/18670	0.2009	0.4163	0.3203	NAMPT/CDK6/PLK2/LMNA/ARNTL/NUAK1/SIRT1/NEK6/HLA-G/ABL1	10
BP	GO:0035023	regulation of Rho protein signal transduction	21/2306	140/18670	0.2011	0.4163	0.3203	ABCA1/ARHGEF10/PDGFRB/NET1/F2R/FGD4/LPAR1/FGD1/FLOT1/ROBO1/ARHGEF5/EPS8/TIAM2/ARHGEF17/ARHGEF12/PLEKHG4/ABL1/ARHGDIB/FARP1/NGEF/PLEKHG2	21
BP	GO:0060078	regulation of postsynaptic membrane potential	21/2306	140/18670	0.2011	0.4163	0.3203	ADORA2A/SSH1/RAB3GAP1/GRIA3/MEF2C/CDK5/RGS4/ADORA1/ABAT/DGKI/P2RX3/CHRNB1/DLG4/GABRA3/GRIK4/PPP3CA/GRIN3A/DVL1/P2RX7/TMEM108/RGS7BP	21
BP	GO:0002067	glandular epithelial cell differentiation	8/2306	46/18670	0.2015	0.4163	0.3203	BMP2/CDK6/BMP4/RXRA/ARNTL/GATA6/WNT5A/TP63	8
BP	GO:0022602	ovulation cycle process	8/2306	46/18670	0.2015	0.4163	0.3203	EREG/AFP/SLIT2/TGFB2/SIRT1/FZD4/PTX3/ZNF830	8
BP	GO:0035196	production of miRNAs involved in gene silencing by miRNA	8/2306	46/18670	0.2015	0.4163	0.3203	ZC3H12A/BMP4/ADAR/ZC3H7A/PRKRA/DDX5/PPP3CA/NCOR2	8
BP	GO:0050919	negative chemotaxis	8/2306	46/18670	0.2015	0.4163	0.3203	NTN1/SLIT2/SEMA4D/FLRT2/ROBO1/WNT5A/FLRT3/SEMA4F	8
BP	GO:0099172	presynapse organization	8/2306	46/18670	0.2015	0.4163	0.3203	FZD1/GPC4/WNT5A/VPS35/ARF6/LRFN4/DVL1/PCDH17	8
BP	GO:1990928	response to amino acid starvation	8/2306	46/18670	0.2015	0.4163	0.3203	SESN1/SLC38A2/FAS/EIF2AK4/SESN3/SESN2/KPTN/CDKN1A	8
BP	GO:0045661	regulation of myoblast differentiation	9/2306	53/18670	0.2017	0.4163	0.3203	CXCL10/BMP4/CXCL9/MEF2C/AKIRIN1/RANBP3L/TNF/ID3/TBX3	9
BP	GO:0045851	pH reduction	9/2306	53/18670	0.2017	0.4163	0.3203	ATP6V1E2/ATP6V0B/RAB38/ATP6V0E2/PPT1/SLAMF8/DMXL1/ROGDI/ATP6V1E1	9
BP	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	9/2306	53/18670	0.2017	0.4163	0.3203	PARP14/GPRC5A/SOCS1/SOCS3/SEMA4D/ERRFI1/SPINK1/PRKCD/CBLB	9
BP	GO:1902475	L-alpha-amino acid transmembrane transport	9/2306	53/18670	0.2017	0.4163	0.3203	SLC7A2/SLC43A2/SLC7A11/ARL6IP5/SLC3A2/RGS2/RGS4/CLN8/SLC38A1	9
BP	GO:1905517	macrophage migration	9/2306	53/18670	0.2017	0.4163	0.3203	CCL5/CCL2/CSF1/CMKLR1/CCL3/THBS1/AKIRIN1/SLAMF8/CYP19A1	9
BP	GO:0010660	regulation of muscle cell apoptotic process	15/2306	96/18670	0.2018	0.4164	0.3204	SOD2/ZC3H12A/CFLAR/IL12A/CAMK2D/PDE1A/STK4/EDN1/SIRT1/MIR19B2/MIR1-2/PPARG/MIR199A2/IGF1/CAPN2	15
BP	GO:0051258	protein polymerization	40/2306	283/18670	0.2019	0.4165	0.3205	ICAM1/MX1/MX2/ARPC1A/DBN1/PAK1/CDC42EP1/ARHGAP18/ACTR3/CDC42EP3/SLIT2/MYADM/ARHGAP28/FMN2/RDX/DCTN1/TTC17/CLIP3/ARPC2/CAPZA2/ARF6/ARF1/PFN2/EPS8/GSN/TRIM6/DIAPH1/PRKCD/GMFB/ABL1/MIR214/ACTR2/TMOD2/CASQ1/PLEKHG2/MID1IP1/MAGEL2/CAMSAP1/UBE2S/TUBGCP4	40
BP	GO:0009743	response to carbohydrate	33/2306	230/18670	0.2023	0.4172	0.321	ICAM1/NAMPT/PTGS2/IL1B/ENSA/ERN1/PPARGC1A/GJD3/GIP/CYBA/THBS1/MAPK13/TCF7L2/RAB11FIP2/ITGA2/LRP5/ATG7/KCNB1/SESN2/P2RX3/DYNLL1/SPARC/BRSK2/EIF2B5/EIF2B4/ME1/GYS2/PPP3CA/PDK3/GAS6/SRI/RMI1/ADRA2A	33
BP	GO:0031334	positive regulation of protein complex assembly	38/2306	268/18670	0.2032	0.4187	0.3221	BID/ICAM1/MMP1/CSF2/MMP3/ABCA1/FSCN1/ARPC1A/VEGFA/PAK1/GBP5/CDC42EP1/ACTR3/RPA2/CDC42EP3/FNIP2/BCLAF1/FMN2/FNIP1/PMAIP1/ERCC2/DCTN1/CAND1/DDB2/MITF/ARPC2/ARF6/ARF1/PFN2/ARHGEF5/GSN/TNF/SUB1/ASAP1/GTF2H5/GMFB/ACTR2/MAGEL2	38
BP	GO:0071772	response to BMP	25/2306	170/18670	0.2032	0.4187	0.3221	BMP2/BMP4/GREM2/FZD1/BMPR2/MSX2/BMPER/HIPK2/GATA6/GDF5/WNT5A/SULF1/GDF15/HES5/FBN1/DDX5/GATA3/FST/ABL1/CTDSPL2/MYH6/ENG/GDF6/USP9X/SMAD9	25
BP	GO:0071773	cellular response to BMP stimulus	25/2306	170/18670	0.2032	0.4187	0.3221	BMP2/BMP4/GREM2/FZD1/BMPR2/MSX2/BMPER/HIPK2/GATA6/GDF5/WNT5A/SULF1/GDF15/HES5/FBN1/DDX5/GATA3/FST/ABL1/CTDSPL2/MYH6/ENG/GDF6/USP9X/SMAD9	25
BP	GO:0006497	protein lipidation	14/2306	89/18670	0.2049	0.4219	0.3246	ABCA1/UGCG/PIGV/WIPI1/RAB3GAP1/ZDHHC16/CLIP3/ATG7/MPPE1/PIGK/WDR45/PIGS/ZDHHC18/NMT2	14
BP	GO:0007411	axon guidance	39/2306	276/18670	0.2059	0.4239	0.3261	TUBB3/NEXN/ZSWIM4/NTN1/PIK3CD/PRKCA/VEGFA/FYN/SLIT2/BMPR2/DOK5/SEMA4D/CHN1/EFNB1/FLRT2/ROBO1/CDK5/WNT5A/ENAH/FLRT3/ETV1/PTPRM/PLXND1/GATA3/CRMP1/EXT1/DOK4/NPTN/YTHDF1/PTPN11/EPHA1/FEZ2/PALLD/SEMA4F/MYH10/CDH4/DVL1/MYCBP2/NFIB	39
BP	GO:0009451	RNA modification	24/2306	163/18670	0.2073	0.426	0.3277	WTAP/APOBEC3G/FTO/ELP4/ADAR/PUS7L/APOBEC3H/THADA/QTRT1/METTL6/SEPHS1/PUS10/NSUN3/PUS7/RBM15/ALKBH8/LCMT2/ADARB1/APOBEC3F/CDKAL1/MEPCE/TRMU/OSGEPL1/FTSJ3	24
BP	GO:2001257	regulation of cation channel activity	26/2306	178/18670	0.2076	0.426	0.3277	CCL2/PPARGC1A/DAPK1/CTSS/GSTO1/RRAD/CALM1/PDE4D/CAMK2D/PKD2/ANK3/GRIA3/MMP9/MEF2C/GEM/STAC/CALM2/MIR1-2/DLG4/STIM1/FKBP1A/PDE4B/NPPA/CNIH2/SRI/CASQ1	26
BP	GO:0071158	positive regulation of cell cycle arrest	13/2306	82/18670	0.2079	0.426	0.3277	ID2/PLK2/PKD2/PRMT1/GATA6/CARM1/BTG2/ARID3A/CNOT8/CDKN1A/TFDP1/MYBBP1A/FOXO4	13
BP	GO:0048706	embryonic skeletal system development	19/2306	126/18670	0.2088	0.426	0.3277	SIX1/BMP4/IRX5/COL1A1/RDH10/HOXA11/SULF2/HOXD9/SIX4/MEF2C/WNT5A/SULF1/HOXD3/OSR2/HOXA9/HSD17B7/HOXB7/EXT1/OSR1	19
BP	GO:0032414	positive regulation of ion transmembrane transporter activity	16/2306	104/18670	0.2096	0.426	0.3277	CCL2/CNKSR3/CTSS/GSTO1/CALM1/PKD2/ANK3/COX17/STAC/RGN/CALM2/ACTN4/MIR1-2/STIM1/NPPA/CASQ1	16
BP	GO:0070585	protein localization to mitochondrion	21/2306	141/18670	0.2105	0.426	0.3277	BID/PPP3CC/PDCD5/DNAJA1/HK2/DNAJC19/PMAIP1/MIPEP/ARIH2/TOMM34/DNAJC15/RHOU/TP63/PARL/YWHAH/BAP1/GRPEL1/GRPEL2/CHCHD4/TFDP1/TIMM17B	21
BP	GO:0002087	regulation of respiratory gaseous exchange by neurological system process	3/2306	13/18670	0.2106	0.426	0.3277	GLS/ADORA1/TSHZ3	3
BP	GO:0002281	macrophage activation involved in immune response	3/2306	13/18670	0.2106	0.426	0.3277	IL33/HAVCR2/TICAM1	3
BP	GO:0002679	respiratory burst involved in defense response	3/2306	13/18670	0.2106	0.426	0.3277	PIK3CD/SLAMF8/DUSP10	3
BP	GO:0003084	positive regulation of systemic arterial blood pressure	3/2306	13/18670	0.2106	0.426	0.3277	NR2F2/CYBA/ADORA1	3
BP	GO:0003306	Wnt signaling pathway involved in heart development	3/2306	13/18670	0.2106	0.426	0.3277	BMP2/MIR19B2/WNT5A	3
BP	GO:0007494	midgut development	3/2306	13/18670	0.2106	0.426	0.3277	WNT5A/ASS1/CPS1	3
BP	GO:0009143	nucleoside triphosphate catabolic process	3/2306	13/18670	0.2106	0.426	0.3277	ADA/ENPP1/NUDT1	3
BP	GO:0009635	response to herbicide	3/2306	13/18670	0.2106	0.426	0.3277	ZC3H12A/DAXX/MAPK13	3
BP	GO:0010763	positive regulation of fibroblast migration	3/2306	13/18670	0.2106	0.426	0.3277	PAK1/THBS1/AKAP12	3
BP	GO:0010838	positive regulation of keratinocyte proliferation	3/2306	13/18670	0.2106	0.426	0.3277	HAS2/TP63/FGF10	3
BP	GO:0016558	protein import into peroxisome matrix	3/2306	13/18670	0.2106	0.426	0.3277	LONP2/PEX1/PEX26	3
BP	GO:0019627	urea metabolic process	3/2306	13/18670	0.2106	0.426	0.3277	ASS1/CEBPA/CPS1	3
BP	GO:0031953	negative regulation of protein autophosphorylation	3/2306	13/18670	0.2106	0.426	0.3277	ENPP1/ERRFI1/ENG	3
BP	GO:0033127	regulation of histone phosphorylation	3/2306	13/18670	0.2106	0.426	0.3277	IL1B/RPS6KA4/AKAP8	3
BP	GO:0034214	protein hexamerization	3/2306	13/18670	0.2106	0.426	0.3277	MAT2A/PANX1/PANX2	3
BP	GO:0034969	histone arginine methylation	3/2306	13/18670	0.2106	0.426	0.3277	PRMT1/CARM1/PRMT3	3
BP	GO:0035723	interleukin-15-mediated signaling pathway	3/2306	13/18670	0.2106	0.426	0.3277	IL15RA/IL15/STAT3	3
BP	GO:0035745	T-helper 2 cell cytokine production	3/2306	13/18670	0.2106	0.426	0.3277	IL6/RSAD2/GATA3	3
BP	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein	3/2306	13/18670	0.2106	0.426	0.3277	PARP14/SOCS1/SOCS3	3
BP	GO:0043970	histone H3-K9 acetylation	3/2306	13/18670	0.2106	0.426	0.3277	KAT2B/GATA3/ZNF451	3
BP	GO:0045820	negative regulation of glycolytic process	3/2306	13/18670	0.2106	0.426	0.3277	PPARGC1A/STAT3/SIRT6	3
BP	GO:0046349	amino sugar biosynthetic process	3/2306	13/18670	0.2106	0.426	0.3277	GFPT2/NAGK/PGM3	3
BP	GO:0046415	urate metabolic process	3/2306	13/18670	0.2106	0.426	0.3277	PRPS1/ABCG2/SLC16A9	3
BP	GO:0048505	regulation of timing of cell differentiation	3/2306	13/18670	0.2106	0.426	0.3277	GDPD5/HES5/HES3	3
BP	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain	3/2306	13/18670	0.2106	0.426	0.3277	FYN/BACE1/ITGA2	3
BP	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway	3/2306	13/18670	0.2106	0.426	0.3277	DOK5/SPRY1/TMEM108	3
BP	GO:0061000	negative regulation of dendritic spine development	3/2306	13/18670	0.2106	0.426	0.3277	PLK2/ASAP1/NGEF	3
BP	GO:0061042	vascular wound healing	3/2306	13/18670	0.2106	0.426	0.3277	TNFAIP3/ADIPOR2/SERPINE1	3
BP	GO:0061430	bone trabecula morphogenesis	3/2306	13/18670	0.2106	0.426	0.3277	COL1A1/MSX2/SEMA4D	3
BP	GO:0061478	response to platelet aggregation inhibitor	3/2306	13/18670	0.2106	0.426	0.3277	AHR/ADCY3/ACTB	3
BP	GO:0070208	protein heterotrimerization	3/2306	13/18670	0.2106	0.426	0.3277	C1QTNF1/COL1A1/COL1A2	3
BP	GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	3/2306	13/18670	0.2106	0.426	0.3277	NFKBIA/TNFAIP3/RIPK2	3
BP	GO:0070831	basement membrane assembly	3/2306	13/18670	0.2106	0.426	0.3277	LAMB1/PHLDB1/PHLDB2	3
BP	GO:0070914	UV-damage excision repair	3/2306	13/18670	0.2106	0.426	0.3277	MC1R/DDB2/SIRT1	3
BP	GO:0071350	cellular response to interleukin-15	3/2306	13/18670	0.2106	0.426	0.3277	IL15RA/IL15/STAT3	3
BP	GO:0071696	ectodermal placode development	3/2306	13/18670	0.2106	0.426	0.3277	SIX1/SIX4/TBX3	3
BP	GO:0071872	cellular response to epinephrine stimulus	3/2306	13/18670	0.2106	0.426	0.3277	PDE4D/SRD5A1/PDE4B	3
BP	GO:0090239	regulation of histone H4 acetylation	3/2306	13/18670	0.2106	0.426	0.3277	AUTS2/SIRT1/IWS1	3
BP	GO:0090481	pyrimidine nucleotide-sugar transmembrane transport	3/2306	13/18670	0.2106	0.426	0.3277	SLC35A1/SLC35B4/SLC35B1	3
BP	GO:0090594	inflammatory response to wounding	3/2306	13/18670	0.2106	0.426	0.3277	IL1A/F2R/SIGLEC10	3
BP	GO:0090677	reversible differentiation	3/2306	13/18670	0.2106	0.426	0.3277	SOD2/MIR1-2/MIR214	3
BP	GO:0098712	L-glutamate import across plasma membrane	3/2306	13/18670	0.2106	0.426	0.3277	SLC7A11/ARL6IP5/CLN8	3
BP	GO:0046173	polyol biosynthetic process	12/2306	75/18670	0.2107	0.426	0.3277	AKR1B1/PLCD3/FGF2/PLCE1/PLCD1/GCH1/CYP27B1/IMPA2/PLCB4/ITPKA/IP6K3/PTS	12
BP	GO:0005996	monosaccharide metabolic process	41/2306	292/18670	0.211	0.426	0.3277	AKR1B1/OAS1/PPARGC1A/C1QTNF1/FOXO1/SLC2A1/HK2/PPP1R3F/ACACB/GALM/GSTO1/ENO2/ADPGK/COX11/IRS1/NFE2L1/PGM2L1/DYRK2/GLB1/PHLDA2/ENPP1/PMAIP1/CPT1A/KAT2B/NISCH/CYB5A/LRP5/SIRT1/CRYL1/RGN/SESN2/TNF/PDHB/ALDH5A1/DUSP12/PDK3/SLC35B4/SIK1/IGF1/GNMT/ALDOC	41
BP	GO:0006779	porphyrin-containing compound biosynthetic process	5/2306	26/18670	0.2114	0.426	0.3277	SLC11A2/NFE2L1/ALAS1/SLC25A39/SUCLA2	5
BP	GO:0006817	phosphate ion transport	5/2306	26/18670	0.2114	0.426	0.3277	CEBPB/XPR1/SLC20A2/ROS1/SLC37A1	5
BP	GO:0030194	positive regulation of blood coagulation	5/2306	26/18670	0.2114	0.426	0.3277	PDPN/THBS1/F2R/SERPINE1/SERPINF2	5
BP	GO:0031954	positive regulation of protein autophosphorylation	5/2306	26/18670	0.2114	0.426	0.3277	VEGFA/CALM1/PDGFD/CALM2/PDGFC	5
BP	GO:0033561	regulation of water loss via skin	5/2306	26/18670	0.2114	0.426	0.3277	CLDN1/UGCG/KRT16/TP63/FLG	5
BP	GO:0042044	fluid transport	5/2306	26/18670	0.2114	0.426	0.3277	CSF2/AQP9/EDN1/AQP7/HAS2	5
BP	GO:0042745	circadian sleep/wake cycle	5/2306	26/18670	0.2114	0.426	0.3277	CSF2/ADORA2A/ADA/SRD5A1/ADORA1	5
BP	GO:0051125	regulation of actin nucleation	5/2306	26/18670	0.2114	0.426	0.3277	FMN2/ARF1/GSN/GMFB/MAGEL2	5
BP	GO:0051497	negative regulation of stress fiber assembly	5/2306	26/18670	0.2114	0.426	0.3277	PPFIA1/ARHGAP28/PHLDB2/TACSTD2/WASF2	5
BP	GO:0055003	cardiac myofibril assembly	5/2306	26/18670	0.2114	0.426	0.3277	PDGFRB/ACTC1/MYOM1/MYOM3/MYH10	5
BP	GO:0055083	monovalent inorganic anion homeostasis	5/2306	26/18670	0.2114	0.426	0.3277	XPR1/CA12/SLC12A2/ENPP1/ABCC2	5
BP	GO:0070911	global genome nucleotide-excision repair	5/2306	26/18670	0.2114	0.426	0.3277	RAD23B/ERCC2/DDB2/GTF2H5/UBB	5
BP	GO:1900048	positive regulation of hemostasis	5/2306	26/18670	0.2114	0.426	0.3277	PDPN/THBS1/F2R/SERPINE1/SERPINF2	5
BP	GO:1900120	regulation of receptor binding	5/2306	26/18670	0.2114	0.426	0.3277	GREM2/PHLDA2/LDOC1/MMP9/NKX3-1	5
BP	GO:1903959	regulation of anion transmembrane transport	5/2306	26/18670	0.2114	0.426	0.3277	ARL6IP5/THBS1/RGS2/RGS4/OSR1	5
BP	GO:0051961	negative regulation of nervous system development	44/2306	315/18670	0.2115	0.426	0.3278	IL6/GPR37L1/IL1B/ID2/NTN1/MEIS1/DENND5A/PLK2/SLIT2/IRX3/RUFY3/EIF2AK4/DPYSL3/DIXDC1/SEMA4D/LPAR1/DAAM2/CARM1/ASCL2/IFRD1/CDK5/WNT5A/ARF6/SYT4/HES5/MIR137/TNF/YWHAH/APPL2/GPR161/HOOK3/GDI1/ASAP1/CRMP1/RTN4/PPP3CA/DUSP10/ID3/SEMA4F/MIB1/STAT3/MYLIP/NGEF/PRTG	44
BP	GO:0097485	neuron projection guidance	39/2306	277/18670	0.2126	0.4282	0.3294	TUBB3/NEXN/ZSWIM4/NTN1/PIK3CD/PRKCA/VEGFA/FYN/SLIT2/BMPR2/DOK5/SEMA4D/CHN1/EFNB1/FLRT2/ROBO1/CDK5/WNT5A/ENAH/FLRT3/ETV1/PTPRM/PLXND1/GATA3/CRMP1/EXT1/DOK4/NPTN/YTHDF1/PTPN11/EPHA1/FEZ2/PALLD/SEMA4F/MYH10/CDH4/DVL1/MYCBP2/NFIB	39
BP	GO:0048709	oligodendrocyte differentiation	15/2306	97/18670	0.2133	0.4291	0.3302	ID2/TNFRSF1B/CNTNAP1/ERCC2/LPAR1/DAAM2/CDKN2C/CDK5/HES5/GSN/EIF2B5/EIF2B4/DUSP10/PPARG/TSPAN2	15
BP	GO:2001022	positive regulation of response to DNA damage stimulus	15/2306	97/18670	0.2133	0.4291	0.3302	NPAS2/BCLAF1/FMN2/PMAIP1/PARP9/SIRT1/NKX3-1/DDX5/PRKCD/MMS19/SETMAR/ACTR2/FGF10/UIMC1/EYA2	15
BP	GO:0035914	skeletal muscle cell differentiation	11/2306	68/18670	0.2133	0.4291	0.3302	MAFF/SIX1/SAP30/ARNTL/SIX4/MEF2C/AKIRIN1/BTG2/DDX5/MIR1-2/ASB2	11
BP	GO:0030888	regulation of B cell proliferation	10/2306	61/18670	0.2156	0.4333	0.3334	AHR/TNFSF13B/CD40/SLC39A10/ADA/CLCF1/MEF2C/CDKN1A/TICAM1/SASH3	10
BP	GO:0046513	ceramide biosynthetic process	10/2306	61/18670	0.2156	0.4333	0.3334	B4GALT3/UGCG/UGT8/TNF/CLN8/PRKCD/SGMS2/NSMAF/P2RX7/SAMD8	10
BP	GO:1905953	negative regulation of lipid localization	10/2306	61/18670	0.2156	0.4333	0.3334	NFKBIA/IL6/NFKB1/ABCA1/THBS1/MIR19B2/TNF/ABHD5/PPARG/PTPN11	10
BP	GO:0008277	regulation of G protein-coupled receptor signaling pathway	22/2306	149/18670	0.2157	0.4334	0.3334	CCL5/PRKCA/PLCE1/C3/ROCK1/CALM1/ADA/EDN1/FZD2/PPP1R9B/RGS2/RGS16/WNT5A/ARRDC3/RGS4/VPS35/RAMP1/MRAP2/ROCK2/TMOD2/HOMER2/NMT2	22
BP	GO:0010039	response to iron ion	6/2306	33/18670	0.2164	0.4337	0.3337	SLC11A2/ACO1/CCND1/ABAT/CYBRD1/TFF1	6
BP	GO:0032691	negative regulation of interleukin-1 beta production	6/2306	33/18670	0.2164	0.4337	0.3337	ZC3H12A/TNFAIP3/ERRFI1/SERPINB1/PYDC2/IGF1	6
BP	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	6/2306	33/18670	0.2164	0.4337	0.3337	TTC37/EXOSC6/DCP1A/CNOT8/LSM6/PATL1	6
BP	GO:0048011	neurotrophin TRK receptor signaling pathway	6/2306	33/18670	0.2164	0.4337	0.3337	ZFYVE27/SORT1/DOK5/SPRY1/PTPN11/TMEM108	6
BP	GO:0050718	positive regulation of interleukin-1 beta secretion	6/2306	33/18670	0.2164	0.4337	0.3337	RIPK2/PANX1/CCL3/GSDMD/WNT5A/P2RX7	6
BP	GO:0051204	protein insertion into mitochondrial membrane	6/2306	33/18670	0.2164	0.4337	0.3337	BID/PPP3CC/PMAIP1/TP63/YWHAH/TFDP1	6
BP	GO:1901186	positive regulation of ERBB signaling pathway	6/2306	33/18670	0.2164	0.4337	0.3337	EREG/TGFA/MMP9/ADORA1/RTN4/ADRA2A	6
BP	GO:2000352	negative regulation of endothelial cell apoptotic process	6/2306	33/18670	0.2164	0.4337	0.3337	ICAM1/TNFAIP3/GATA3/SERPINE1/ABL1/GAS6	6
BP	GO:0032411	positive regulation of transporter activity	17/2306	112/18670	0.2168	0.434	0.3339	CCL2/CNKSR3/CTSS/GSTO1/CALM1/PKD2/ANK3/COX17/STAC/RGN/CALM2/ACTN4/MIR1-2/STIM1/PRKCD/NPPA/CASQ1	17
BP	GO:0043279	response to alkaloid	17/2306	112/18670	0.2168	0.434	0.3339	ICAM1/ADORA2A/PPARGC1A/FADD/OXTR/ADA/HNMT/PPP1R9B/CDK5/RGS4/ATG7/BCL2L1/ABAT/TMED10/PPARG/HOMER2/CASP7	17
BP	GO:0048593	camera-type eye morphogenesis	17/2306	112/18670	0.2168	0.434	0.3339	AHI1/MEIS1/ALDH1A3/VEGFA/BMP4/IRX5/BCAR3/HIPK2/LRP5/WNT5A/SHROOM2/FJX1/TOPORS/PTPRM/ATP8A2/ARID1A/RDH13	17
BP	GO:0001843	neural tube closure	14/2306	90/18670	0.2169	0.434	0.3339	BMP4/FZD1/SHROOM3/FZD2/TGFB2/WNT5A/PTK7/ARID1A/SDC4/ABL1/BCL10/RALA/DVL1/DVL2	14
BP	GO:0034333	adherens junction assembly	14/2306	90/18670	0.2169	0.434	0.3339	CORO1C/VEGFA/ROCK1/VCL/THBS1/TRIP6/ITGA2/DUSP3/PHLDB2/FERMT2/COL16A1/SDC4/ABL1/ROCK2	14
BP	GO:0002763	positive regulation of myeloid leukocyte differentiation	9/2306	54/18670	0.2174	0.4341	0.334	LIF/ID2/TRIB1/CSF1/PRKCA/FADD/TMEM64/ACIN1/TNF	9
BP	GO:0006584	catecholamine metabolic process	9/2306	54/18670	0.2174	0.4341	0.334	AKR1B1/EPAS1/PNKD/GCH1/TGFB2/MOXD1/VPS35/ABAT/GATA3	9
BP	GO:0009712	catechol-containing compound metabolic process	9/2306	54/18670	0.2174	0.4341	0.334	AKR1B1/EPAS1/PNKD/GCH1/TGFB2/MOXD1/VPS35/ABAT/GATA3	9
BP	GO:0043392	negative regulation of DNA binding	9/2306	54/18670	0.2174	0.4341	0.334	NFKBIA/ID2/ZFP90/MSX2/SUMO3/SP100/ID3/SRI/ZNF675	9
BP	GO:0045747	positive regulation of Notch signaling pathway	9/2306	54/18670	0.2174	0.4341	0.334	KIT/TGFB2/KAT2B/ROBO1/TP63/HES5/ELF3/FGF10/STAT3	9
BP	GO:0097345	mitochondrial outer membrane permeabilization	9/2306	54/18670	0.2174	0.4341	0.334	BID/PPP3CC/PMAIP1/TP63/ACAA2/YWHAH/TMEM14A/TFDP1/EYA2	9
BP	GO:0009260	ribonucleotide biosynthetic process	41/2306	293/18670	0.2176	0.4343	0.3342	PID1/PPARGC1A/SLC2A6/HK2/ACACB/ELOVL5/ENO2/ADPGK/NUP133/AK1/SCD/ELOVL7/AMPD3/PGM2L1/ACAT1/PPT1/ADCY7/ACACA/NME5/ACSL5/CBR4/ADCY9/ADCY3/ELOVL2/IMPDH2/PPCS/HSD17B12/PDHB/PAPSS1/GUK1/PGAM4/NPR2/PDK3/NPPA/NUP35/IGF1/STAT3/ALDOC/P2RX7/SIRT6/ELOVL3	41
BP	GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	7/2306	40/18670	0.2184	0.4355	0.3351	ZC3H12A/IL33/IL7R/IL4R/HLA-F/HAVCR2/HLA-G	7
BP	GO:2000008	regulation of protein localization to cell surface	7/2306	40/18670	0.2184	0.4355	0.3351	GPD1L/STX3/MAP1A/ARF6/TNF/TOR1A/PICALM	7
BP	GO:0030574	collagen catabolic process	8/2306	47/18670	0.2185	0.4355	0.3351	MMP1/MMP3/CTSS/MMP9/MMP17/MMP11/MMP27/MMP24	8
BP	GO:0070849	response to epidermal growth factor	8/2306	47/18670	0.2185	0.4355	0.3351	CFLAR/COL1A1/ZFP36/ZFP36L2/ERRFI1/SNAI2/DUSP3/PTPN11	8
BP	GO:0007034	vacuolar transport	21/2306	142/18670	0.2201	0.4386	0.3375	CHMP1B/SORT1/CHMP4B/GNPTAB/NDFIP1/VPS37D/GCC2/VPS36/RHOB/VPS37C/IGF2R/VPS35/ARF1/HOOK3/TMEM106B/CHMP5/VAMP7/NDFIP2/M6PR/AKTIP/NEDD4	21
BP	GO:0045913	positive regulation of carbohydrate metabolic process	13/2306	83/18670	0.2205	0.4393	0.338	NFKB1/PPARGC1A/FOXO1/IRS1/DYRK2/PMAIP1/KAT2B/HAS2/SIRT1/RGN/DUSP12/IGF1/P2RX7	13
BP	GO:0030509	BMP signaling pathway	23/2306	157/18670	0.2206	0.4393	0.338	BMP2/BMP4/GREM2/FZD1/BMPR2/MSX2/BMPER/HIPK2/GDF5/WNT5A/SULF1/GDF15/HES5/FBN1/DDX5/FST/ABL1/CTDSPL2/MYH6/ENG/GDF6/USP9X/SMAD9	23
BP	GO:0001841	neural tube formation	16/2306	105/18670	0.2209	0.4395	0.3381	BMP4/FZD1/SHROOM3/STK4/FZD2/TGFB2/WNT5A/PTK7/ARID1A/SDC4/ABL1/BCL10/RALA/MIB1/DVL1/DVL2	16
BP	GO:0006641	triglyceride metabolic process	16/2306	105/18670	0.2209	0.4395	0.3381	GK/LPIN1/C3/INSIG2/SLC22A4/FABP3/LIPG/CPT1A/SIRT1/RGN/ABHD5/GPAM/CPS1/PTPN11/SIK1/TBL1XR1	16
BP	GO:0008593	regulation of Notch signaling pathway	16/2306	105/18670	0.2209	0.4395	0.3381	NFKBIA/GDPD5/KIT/IL6ST/BEND6/TGFB2/KAT2B/ROBO1/TP63/HES5/ELF3/PEAR1/FGF10/STAT3/GALNT11/SLC35C1	16
BP	GO:0002698	negative regulation of immune effector process	18/2306	120/18670	0.2233	0.4439	0.3415	ZC3H12A/IL33/IL7R/HLA-E/IL4R/TSPAN6/HLA-F/IRAK3/ITCH/DHX58/TGFB2/MICB/HAVCR2/TNF/SLAMF8/HLA-G/DUSP10/TRIM38	18
BP	GO:0006721	terpenoid metabolic process	18/2306	120/18670	0.2233	0.4439	0.3415	AKR1B1/ALDH1A3/CYP27C1/GPC4/RDH10/RDH8/HSPG2/DHRS3/SRD5A1/ADH5/SDC2/CYP1A2/SDC4/PECR/RDH13/ADH1C/CYP2C19/CYP2S1	18
BP	GO:0072089	stem cell proliferation	18/2306	120/18670	0.2233	0.4439	0.3415	FGF2/VEGFA/EML1/SMARCD3/PIM1/SOX5/ARIH2/SNAI2/YAP1/DAGLA/WNT5A/MIR137/NUMBL/DAGLB/FERMT1/SIRT6/AKNA/TBX3	18
BP	GO:0072524	pyridine-containing compound metabolic process	28/2306	195/18670	0.2239	0.4449	0.3423	NAMPT/PTGS2/PPARGC1A/SLC2A6/GPD1L/KYNU/IDO1/HK2/ENO2/ADPGK/NUP133/IDH1/PGM2L1/NNMT/PNPO/PSAT1/PARP9/LDHB/PDHB/ME1/PGAM4/PDXP/NUP35/IGF1/STAT3/ALDOC/P2RX7/SIRT6	28
BP	GO:0007492	endoderm development	12/2306	76/18670	0.2241	0.445	0.3424	BMP4/LAMB1/ITGB5/ITGA4/COL5A2/GATA6/MMP9/SOX7/EXT1/BPTF/COL5A1/SSBP3	12
BP	GO:0042278	purine nucleoside metabolic process	12/2306	76/18670	0.2241	0.445	0.3424	RAB23/AMPD3/NUDT18/ADA/NT5C2/NME5/IMPDH2/GAMT/GUK1/MTAP/PRTFDC1/GNMT	12
BP	GO:0001824	blastocyst development	15/2306	98/18670	0.2251	0.4464	0.3435	PPP4R4/TM4SF1/ADA/TET1/STMN3/AKAP3/JUNB/ELF3/ZNF830/RTN4/DAD1/IGF1/TBL1XR1/CAPN2/NPM2	15
BP	GO:0002042	cell migration involved in sprouting angiogenesis	15/2306	98/18670	0.2251	0.4464	0.3435	PTGS2/FGF2/VEGFA/PLK2/SLIT2/RHOJ/KLF4/THBS1/CARD10/PIK3R3/STARD13/MEOX2/ROBO1/MIR19B2/ABL1	15
BP	GO:0031341	regulation of cell killing	15/2306	98/18670	0.2251	0.4464	0.3435	CXCL6/ICAM1/IL7R/HLA-E/IL12A/HLA-F/FADD/HLA-A/MICB/HAVCR2/HLA-G/NCR1/P2RX7/HLA-B/HLA-H	15
BP	GO:0050777	negative regulation of immune response	22/2306	150/18670	0.2252	0.4464	0.3435	ZC3H12A/TNFAIP3/IL33/PARP14/IL7R/TNFRSF14/HLA-E/IL4R/HLA-F/IRAK3/ADAR/DHX58/TGFB2/STAT6/PSMA1/HAVCR2/TNF/SLAMF8/TRAFD1/HLA-G/DUSP10/PPARG	22
BP	GO:0072525	pyridine-containing compound biosynthetic process	22/2306	150/18670	0.2252	0.4464	0.3435	NAMPT/PTGS2/PPARGC1A/SLC2A6/KYNU/IDO1/HK2/ENO2/ADPGK/NUP133/PGM2L1/NNMT/PNPO/PSAT1/PARP9/PGAM4/NUP35/IGF1/STAT3/ALDOC/P2RX7/SIRT6	22
BP	GO:0032271	regulation of protein polymerization	31/2306	218/18670	0.2261	0.4481	0.3448	ICAM1/ARPC1A/DBN1/PAK1/CDC42EP1/ARHGAP18/ACTR3/CDC42EP3/SLIT2/MYADM/ARHGAP28/FMN2/RDX/DCTN1/CLIP3/ARPC2/CAPZA2/ARF6/ARF1/PFN2/EPS8/GSN/PRKCD/GMFB/ABL1/MIR214/ACTR2/TMOD2/PLEKHG2/MAGEL2/CAMSAP1	31
BP	GO:0030166	proteoglycan biosynthetic process	11/2306	69/18670	0.2275	0.4481	0.3448	BMPR2/VCAN/CHST7/TCF7L2/CYTL1/CSGALNACT1/CSGALNACT2/CHST8/EXT1/HS2ST1/IGF1	11
BP	GO:0003323	type B pancreatic cell development	4/2306	20/18670	0.228	0.4481	0.3448	CDK6/BMP4/ARNTL/WNT5A	4
BP	GO:0007620	copulation	4/2306	20/18670	0.228	0.4481	0.3448	PI3/OXTR/ADA/ABAT	4
BP	GO:0009264	deoxyribonucleotide catabolic process	4/2306	20/18670	0.228	0.4481	0.3448	NUDT18/ADA/NUDT1/MBD4	4
BP	GO:0010738	regulation of protein kinase A signaling	4/2306	20/18670	0.228	0.4481	0.3448	AKAP12/MC1R/IAPP/PJA2	4
BP	GO:0016137	glycoside metabolic process	4/2306	20/18670	0.228	0.4481	0.3448	AKR1B1/NAGA/GLA/CBR4	4
BP	GO:0030903	notochord development	4/2306	20/18670	0.228	0.4481	0.3448	COL5A2/YAP1/WNT5A/ID3	4
BP	GO:0032042	mitochondrial DNA metabolic process	4/2306	20/18670	0.228	0.4481	0.3448	PPARGC1A/ATG7/SESN2/POLG2	4
BP	GO:0032769	negative regulation of monooxygenase activity	4/2306	20/18670	0.228	0.4481	0.3448	NFKB1/GLA/CYP27B1/CNR2	4
BP	GO:0033194	response to hydroperoxide	4/2306	20/18670	0.228	0.4481	0.3448	DAPK1/TP53INP1/PRKCD/OXR1	4
BP	GO:0033630	positive regulation of cell adhesion mediated by integrin	4/2306	20/18670	0.228	0.4481	0.3448	CCL5/PODXL/TGFB2/FERMT1	4
BP	GO:0043369	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment	4/2306	20/18670	0.228	0.4481	0.3448	IL6/CYLD/STAT6/STAT3	4
BP	GO:0043691	reverse cholesterol transport	4/2306	20/18670	0.228	0.4481	0.3448	ABCA1/LIPG/ABCA5/MIR19B2	4
BP	GO:0046655	folic acid metabolic process	4/2306	20/18670	0.228	0.4481	0.3448	MTHFD2L/MTHFD2/SLC19A1/ALDH1L2	4
BP	GO:0048148	behavioral response to cocaine	4/2306	20/18670	0.228	0.4481	0.3448	FADD/CDK5/ABAT/HOMER2	4
BP	GO:0051016	barbed-end actin filament capping	4/2306	20/18670	0.228	0.4481	0.3448	RDX/CAPZA2/EPS8/GSN	4
BP	GO:0061162	establishment of monopolar cell polarity	4/2306	20/18670	0.228	0.4481	0.3448	FSCN1/WNT5A/PTK7/CDC42	4
BP	GO:0070932	histone H3 deacetylation	4/2306	20/18670	0.228	0.4481	0.3448	SIRT1/PER1/SMARCAD1/SIRT6	4
BP	GO:0071397	cellular response to cholesterol	4/2306	20/18670	0.228	0.4481	0.3448	ABCA1/NFE2L1/OSBPL7/GRAMD1A	4
BP	GO:0071636	positive regulation of transforming growth factor beta production	4/2306	20/18670	0.228	0.4481	0.3448	PTGS2/MYB/THBS1/SERPINF2	4
BP	GO:0090195	chemokine secretion	4/2306	20/18670	0.228	0.4481	0.3448	IL33/IL4R/MBP/TNF	4
BP	GO:0097503	sialylation	4/2306	20/18670	0.228	0.4481	0.3448	ST3GAL1/ST8SIA1/ST3GAL3/ST3GAL4	4
BP	GO:0097734	extracellular exosome biogenesis	4/2306	20/18670	0.228	0.4481	0.3448	SDCBP/SDC4/ATP13A2/PDCD6IP	4
BP	GO:1900151	regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	4/2306	20/18670	0.228	0.4481	0.3448	ZFP36/ZFP36L2/PABPC1/BTG2	4
BP	GO:1900424	regulation of defense response to bacterium	4/2306	20/18670	0.228	0.4481	0.3448	CXCL6/CYBA/HAVCR2/MAPKBP1	4
BP	GO:1902993	positive regulation of amyloid precursor protein catabolic process	4/2306	20/18670	0.228	0.4481	0.3448	IFNGR1/TNF/ROCK2/PICALM	4
BP	GO:0045639	positive regulation of myeloid cell differentiation	14/2306	91/18670	0.2293	0.4505	0.3466	LIF/ID2/TRIB1/CSF1/ISG15/PRKCA/STAT1/ETS1/FADD/PRMT1/TMEM64/ACIN1/TNF/STAT3	14
BP	GO:0002260	lymphocyte homeostasis	10/2306	62/18670	0.2307	0.4528	0.3484	TNFAIP3/TNFSF13B/FADD/ADA/PMAIP1/MEF2C/CACNA1F/ABL1/BCL10/P2RX7	10
BP	GO:0003407	neural retina development	10/2306	62/18670	0.2307	0.4528	0.3484	AHI1/IRX5/SMARCD3/HIPK2/TGFB2/FJX1/TOPORS/PTPRM/ATP8A2/RDH13	10
BP	GO:0010676	positive regulation of cellular carbohydrate metabolic process	10/2306	62/18670	0.2307	0.4528	0.3484	PPARGC1A/FOXO1/IRS1/DYRK2/PMAIP1/KAT2B/SIRT1/RGN/DUSP12/IGF1	10
BP	GO:1902686	mitochondrial outer membrane permeabilization involved in programmed cell death	10/2306	62/18670	0.2307	0.4528	0.3484	BID/PPP3CC/PPIF/PMAIP1/TP63/ACAA2/YWHAH/TMEM14A/TFDP1/EYA2	10
BP	GO:0042391	regulation of membrane potential	59/2306	434/18670	0.2324	0.4558	0.3506	BID/PID1/KCNN4/ADORA2A/FHL1/GPD1L/POPDC2/CNTNAP1/CAMK2D/ARL6IP5/ANK3/SSH1/EDN1/RAB3GAP1/PMAIP1/GRIA3/ABCD1/HCN4/HTR3B/MEF2C/CDK5/RGS4/ADORA1/KCNB1/BCL2L1/ABAT/DGKI/P2RX3/CACNA1B/YWHAH/CHRNB1/PXK/ATP2A2/MIR1-2/DLG4/CNR2/USP53/GABRA3/GRIK4/PPP3CA/GRIN3A/SNTA1/ABL1/UBB/KCND3/SLC26A3/SLC25A33/ATP1A4/NPPA/KCNK17/CNIH2/DVL1/SRI/P2RX7/TMEM108/RGS7BP/SLC25A36/NEDD4/PIAS3	59
BP	GO:1901606	alpha-amino acid catabolic process	16/2306	106/18670	0.2324	0.4558	0.3506	DDAH1/KYNU/GLS/IDO1/HIBCH/IL4I1/FAH/ACAT1/GLUD1/HNMT/AADAT/HIBADH/AMT/ALDH7A1/DDAH2/BCAT2	16
BP	GO:0051453	regulation of intracellular pH	13/2306	84/18670	0.2335	0.4574	0.3519	ATP6V1E2/ATP6V0B/RAB38/ATP6V0E2/PPT1/TMEM175/SLAMF8/DMXL1/SLC26A3/ROGDI/ATP6V1E1/SLC9A9/TMEM165	13
BP	GO:0002090	regulation of receptor internalization	9/2306	55/18670	0.2336	0.4574	0.3519	AHI1/VEGFA/ANKRD13A/MKLN1/SDCBP/FLOT1/ARF1/DLG4/MIR199A2	9
BP	GO:0006383	transcription by RNA polymerase III	9/2306	55/18670	0.2336	0.4574	0.3519	POLR3GL/POLR3D/IVNS1ABP/CEBPA/ELL/POLR3K/POLR1C/GTF3C4/GTF3A	9
BP	GO:0044380	protein localization to cytoskeleton	9/2306	55/18670	0.2336	0.4574	0.3519	MID1/MAP1A/CEP250/HOOK3/DIAPH1/MAPRE2/MARK4/DVL1/SNX10	9
BP	GO:0046456	icosanoid biosynthetic process	9/2306	55/18670	0.2336	0.4574	0.3519	PTGS2/IL1B/PTGES/PLA2G4A/EDN1/PRG3/SIRT1/PTGS1/MGST2	9
BP	GO:0006475	internal protein amino acid acetylation	24/2306	166/18670	0.2343	0.4582	0.3526	IL1B/LIF/BRPF3/PPARGC1A/AUTS2/SET/DR1/KAT2B/SNAI2/MORF4L2/RPS6KA4/YEATS2/SIRT1/MSL1/GATA3/IWS1/SETD5/TAF6L/PER1/GTF3C4/MSL3/ZNF451/TADA3/PHF10	24
BP	GO:0000272	polysaccharide catabolic process	5/2306	27/18670	0.2351	0.4582	0.3526	PYGL/CALM1/PGM2L1/PHKB/PHKA2	5
BP	GO:0000460	maturation of 5.8S rRNA	5/2306	27/18670	0.2351	0.4582	0.3526	RCL1/UTP20/BOP1/URB1/FTSJ3	5
BP	GO:0001964	startle response	5/2306	27/18670	0.2351	0.4582	0.3526	ADORA2A/BACE1/NPAS1/GRIN3A/DVL1	5
BP	GO:0006730	one-carbon metabolic process	5/2306	27/18670	0.2351	0.4582	0.3526	MTHFD2L/MAT2A/MTHFD2/ALDH1L2/GNMT	5
BP	GO:0006735	NADH regeneration	5/2306	27/18670	0.2351	0.4582	0.3526	HK2/ENO2/ADPGK/PGM2L1/ALDOC	5
BP	GO:0034067	protein localization to Golgi apparatus	5/2306	27/18670	0.2351	0.4582	0.3526	GBP5/SYS1/GCC2/OPTN/BICD2	5
BP	GO:0035883	enteroendocrine cell differentiation	5/2306	27/18670	0.2351	0.4582	0.3526	CDK6/BMP4/ARNTL/GATA6/WNT5A	5
BP	GO:0050820	positive regulation of coagulation	5/2306	27/18670	0.2351	0.4582	0.3526	PDPN/THBS1/F2R/SERPINE1/SERPINF2	5
BP	GO:0061621	canonical glycolysis	5/2306	27/18670	0.2351	0.4582	0.3526	HK2/ENO2/ADPGK/PGM2L1/ALDOC	5
BP	GO:0061718	glucose catabolic process to pyruvate	5/2306	27/18670	0.2351	0.4582	0.3526	HK2/ENO2/ADPGK/PGM2L1/ALDOC	5
BP	GO:0080154	regulation of fertilization	5/2306	27/18670	0.2351	0.4582	0.3526	LHFPL2/NOX5/ZP2/STXBP1/SPINK1	5
BP	GO:0090169	regulation of spindle assembly	5/2306	27/18670	0.2351	0.4582	0.3526	CHMP1B/CHMP4B/GPSM2/RNF4/CHMP5	5
BP	GO:2000191	regulation of fatty acid transport	5/2306	27/18670	0.2351	0.4582	0.3526	IL1B/FABP3/THBS1/EDN1/P2RX7	5
BP	GO:0048562	embryonic organ morphogenesis	40/2306	288/18670	0.2358	0.4589	0.3531	LRIG1/ID2/AHI1/NTN1/MAFB/SIX1/INSIG2/ALDH1A3/BMP4/IRX5/RDH10/PKD2/HOXA11/TTC39C/EDN1/FZD2/HIPK2/YAP1/HOXD9/SETDB2/CEP290/SIX4/MEF2C/WNT5A/PRKRA/FBN1/PTK7/HOXD3/OSR2/ATP8A2/GATA3/HOXB7/ARID1A/ENG/FGF10/MIB1/DVL1/OSR1/DVL2/TBX3	40
BP	GO:0002063	chondrocyte development	8/2306	48/18670	0.2359	0.4589	0.3531	BMPR2/MSX2/SCARA3/SULF2/PTHLH/SULF1/COL6A3/SERPINH1	8
BP	GO:0006111	regulation of gluconeogenesis	8/2306	48/18670	0.2359	0.4589	0.3531	PPARGC1A/FOXO1/KAT2B/SIRT1/SESN2/SLC35B4/SIK1/GNMT	8
BP	GO:0007595	lactation	8/2306	48/18670	0.2359	0.4589	0.3531	VEGFA/HK2/OAS2/CCND1/OXTR/VDR/SOCS2/NCOR2	8
BP	GO:0035272	exocrine system development	8/2306	48/18670	0.2359	0.4589	0.3531	TGFB2/SNAI2/POLB/NKX3-1/TNF/PLXND1/FGF10/NFIB	8
BP	GO:0051653	spindle localization	8/2306	48/18670	0.2359	0.4589	0.3531	ACTR3/FMN2/GPSM2/DCTN1/SPRY1/ACTR2/FGF10/MYH9	8
BP	GO:0072604	interleukin-6 secretion	8/2306	48/18670	0.2359	0.4589	0.3531	ZC3H12A/IL1B/IFIH1/DDX58/MBP/F2R/TNF/GAS6	8
BP	GO:0010955	negative regulation of protein processing	7/2306	41/18670	0.2374	0.4603	0.3542	BIRC3/BIRC2/THBS1/CAST/MAGEA3/SERPINE1/SERPINF2	7
BP	GO:0030835	negative regulation of actin filament depolymerization	7/2306	41/18670	0.2374	0.4603	0.3542	LIMA1/RDX/PLEKHH2/CAPZA2/EPS8/GSN/TMOD2	7
BP	GO:0043403	skeletal muscle tissue regeneration	7/2306	41/18670	0.2374	0.4603	0.3542	CFLAR/IFRD1/AKIRIN1/BIN3/PPP3CA/IGF1/FZD7	7
BP	GO:0090224	regulation of spindle organization	7/2306	41/18670	0.2374	0.4603	0.3542	CHMP1B/CHMP4B/CLTC/GPSM2/DCTN1/RNF4/CHMP5	7
BP	GO:0090279	regulation of calcium ion import	7/2306	41/18670	0.2374	0.4603	0.3542	CCL2/PDGFRB/FYN/PKD2/CCL3/SLC30A1/SPINK1	7
BP	GO:0090317	negative regulation of intracellular protein transport	7/2306	41/18670	0.2374	0.4603	0.3542	RAB23/CDK5/TXN/SP100/GDI1/PKIG/FERMT1	7
BP	GO:1902893	regulation of pri-miRNA transcription by RNA polymerase II	7/2306	41/18670	0.2374	0.4603	0.3542	BMP2/BMP4/TGFB2/GNL3/STAT3/ATOH8/NFIB	7
BP	GO:1903318	negative regulation of protein maturation	7/2306	41/18670	0.2374	0.4603	0.3542	BIRC3/BIRC2/THBS1/CAST/MAGEA3/SERPINE1/SERPINF2	7
BP	GO:0043276	anoikis	6/2306	34/18670	0.2375	0.4603	0.3542	SNAI2/PTRH2/TLE1/SIK1/TFDP1/MYBBP1A	6
BP	GO:0060795	cell fate commitment involved in formation of primary germ layer	6/2306	34/18670	0.2375	0.4603	0.3542	BMP4/KLF4/HOXA11/GATA6/FZD7/EYA2	6
BP	GO:0070050	neuron cellular homeostasis	6/2306	34/18670	0.2375	0.4603	0.3542	IL6/DCTN1/MAP1A/CDK5/ADORA1/TAOK1	6
BP	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	12/2306	77/18670	0.2378	0.4607	0.3545	TTC37/ZFP36/EXOSC6/ZFP36L2/PDE12/DCP1A/PABPC1/BTG2/SAMD4B/CNOT8/LSM6/PATL1	12
BP	GO:0051937	catecholamine transport	12/2306	77/18670	0.2378	0.4607	0.3545	ADORA2A/SLC22A1/OXTR/NISCH/KCNB1/SYT4/ABAT/ACTB/SYT1/SLC22A3/TOR1A/ADRA2A	12
BP	GO:0042752	regulation of circadian rhythm	17/2306	114/18670	0.239	0.4629	0.3561	CSF2/ID2/ADORA2A/PPARGC1A/ADA/ARNTL/CSNK1E/ZFHX3/ADORA1/ATG7/ROCK2/PER1/PPARG/SIK1/USP9X/ARNTL2/MAGEL2	17
BP	GO:0006486	protein glycosylation	36/2306	258/18670	0.2406	0.4656	0.3582	GFPT2/ST3GAL1/ST8SIA1/MAN1A1/B4GALT3/GALNT10/MAN1C1/A4GALT/IL15/TET1/GXYLT1/SERP2/MOGS/POMGNT1/RAMP1/PGM3/GALNT5/MGAT1/MGAT2/GCNT1/TET3/C1GALT1/EXT1/ST3GAL3/ALG3/GALNT4/DAD1/DPY19L4/MUC15/MUC17/ALG13/GALNT11/GALNT1/SLC35C1/TMEM165/ST3GAL4	36
BP	GO:0043413	macromolecule glycosylation	36/2306	258/18670	0.2406	0.4656	0.3582	GFPT2/ST3GAL1/ST8SIA1/MAN1A1/B4GALT3/GALNT10/MAN1C1/A4GALT/IL15/TET1/GXYLT1/SERP2/MOGS/POMGNT1/RAMP1/PGM3/GALNT5/MGAT1/MGAT2/GCNT1/TET3/C1GALT1/EXT1/ST3GAL3/ALG3/GALNT4/DAD1/DPY19L4/MUC15/MUC17/ALG13/GALNT11/GALNT1/SLC35C1/TMEM165/ST3GAL4	36
BP	GO:0006672	ceramide metabolic process	14/2306	92/18670	0.2419	0.4667	0.359	B4GALT3/UGCG/NAGA/GLA/ITGB8/UGT8/TNF/CLN8/ALDH5A1/PRKCD/SGMS2/NSMAF/P2RX7/SAMD8	14
BP	GO:0010517	regulation of phospholipase activity	11/2306	70/18670	0.2421	0.4667	0.359	CCL5/KIT/FGF2/PDGFRB/ANXA8/PPT1/RGS2/LPAR1/GNA13/ABL1/NMUR2	11
BP	GO:0033077	T cell differentiation in thymus	11/2306	70/18670	0.2421	0.4667	0.359	CDK6/IL7R/MAFB/BMP4/FADD/ADA/ZFP36L2/FZD8/GATA3/FZD7/ADAM8	11
BP	GO:0032259	methylation	50/2306	366/18670	0.2422	0.4667	0.359	WTAP/JARID2/MAT2A/AUTS2/RNF20/GSTO1/MYB/DPH5/LMNA/NNMT/PRMT1/TET1/HNMT/THADA/METTL7A/METTL6/SMYD3/CYP1A2/METTL5/CARM1/SETDB2/GAMT/SIRT1/COQ3/COMTD1/AMT/BTG2/MTR/NSUN3/PPM1D/BHMT2/RBM15/PRMT3/TET3/RBBP5/ALKBH8/LCMT2/GATA3/PRDM13/IWS1/PRDM1/SETMAR/SETD5/RLF/MEPCE/GNMT/TPMT/PCMT1/ARID4A/FTSJ3	50
BP	GO:0006338	chromatin remodeling	26/2306	182/18670	0.2424	0.4667	0.359	DAXX/JARID2/PAK1/MYB/SMARCD3/SMARCA5/DR1/KAT2B/SMARCA2/CHD4/TNP2/ZMIZ2/TP63/INO80C/ACTB/GATA3/ARID1A/PBRM1/TAF6L/ITGB3BP/SMARCE1/PSME4/BPTF/SMARCAD1/SIRT6/NPM2	26
BP	GO:0001909	leukocyte mediated cytotoxicity	16/2306	107/18670	0.2441	0.4667	0.359	CXCL6/ICAM1/IL7R/HLA-E/IL12A/HLA-F/FADD/HLA-A/MICB/HAVCR2/HLA-G/NCR1/VAMP7/P2RX7/HLA-B/HLA-H	16
BP	GO:0002523	leukocyte migration involved in inflammatory response	3/2306	14/18670	0.2451	0.4667	0.359	JAM3/SLAMF8/ADAM8	3
BP	GO:0006684	sphingomyelin metabolic process	3/2306	14/18670	0.2451	0.4667	0.359	PRKCD/SGMS2/SAMD8	3
BP	GO:0006999	nuclear pore organization	3/2306	14/18670	0.2451	0.4667	0.359	NUP133/RTN4/NUP35	3
BP	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity	3/2306	14/18670	0.2451	0.4667	0.359	GPRC5A/ERRFI1/CBLB	3
BP	GO:0010457	centriole-centriole cohesion	3/2306	14/18670	0.2451	0.4667	0.359	RTTN/DCTN1/CEP250	3
BP	GO:0010752	regulation of cGMP-mediated signaling	3/2306	14/18670	0.2451	0.4667	0.359	THBS1/NPR2/NPPA	3
BP	GO:0010755	regulation of plasminogen activation	3/2306	14/18670	0.2451	0.4667	0.359	THBS1/SERPINE1/SERPINF2	3
BP	GO:0014819	regulation of skeletal muscle contraction	3/2306	14/18670	0.2451	0.4667	0.359	GSTO1/DMPK/CASQ1	3
BP	GO:0030240	skeletal muscle thin filament assembly	3/2306	14/18670	0.2451	0.4667	0.359	ACTC1/MYOM1/MYOM3	3
BP	GO:0032310	prostaglandin secretion	3/2306	14/18670	0.2451	0.4667	0.359	IL1B/EDN1/P2RX7	3
BP	GO:0035020	regulation of Rac protein signal transduction	3/2306	14/18670	0.2451	0.4667	0.359	AUTS2/STMN3/ARF6	3
BP	GO:0035435	phosphate ion transmembrane transport	3/2306	14/18670	0.2451	0.4667	0.359	XPR1/SLC20A2/SLC37A1	3
BP	GO:0035791	platelet-derived growth factor receptor-beta signaling pathway	3/2306	14/18670	0.2451	0.4667	0.359	PDGFRB/PDGFRL/ABL1	3
BP	GO:0038166	angiotensin-activated signaling pathway	3/2306	14/18670	0.2451	0.4667	0.359	AGTRAP/ROCK1/ROCK2	3
BP	GO:0040034	regulation of development, heterochronic	3/2306	14/18670	0.2451	0.4667	0.359	GDPD5/HES5/HES3	3
BP	GO:0043374	CD8-positive, alpha-beta T cell differentiation	3/2306	14/18670	0.2451	0.4667	0.359	IRF1/SOCS1/CBFB	3
BP	GO:0043558	regulation of translational initiation in response to stress	3/2306	14/18670	0.2451	0.4667	0.359	PPP1R15A/EIF2AK4/DNAJC3	3
BP	GO:0045064	T-helper 2 cell differentiation	3/2306	14/18670	0.2451	0.4667	0.359	IL4R/BCL3/GATA3	3
BP	GO:0045198	establishment of epithelial cell apical/basal polarity	3/2306	14/18670	0.2451	0.4667	0.359	WNT5A/PTK7/CDC42	3
BP	GO:0045591	positive regulation of regulatory T cell differentiation	3/2306	14/18670	0.2451	0.4667	0.359	SOCS1/HLA-G/DUSP10	3
BP	GO:0045605	negative regulation of epidermal cell differentiation	3/2306	14/18670	0.2451	0.4667	0.359	MSX2/TP63/HES5	3
BP	GO:0045836	positive regulation of meiotic nuclear division	3/2306	14/18670	0.2451	0.4667	0.359	MSX2/WNT5A/NPM2	3
BP	GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	3/2306	14/18670	0.2451	0.4667	0.359	APOBEC3G/APOBEC3H/APOBEC3F	3
BP	GO:0046479	glycosphingolipid catabolic process	3/2306	14/18670	0.2451	0.4667	0.359	NAGA/GLA/PRKCD	3
BP	GO:0046855	inositol phosphate dephosphorylation	3/2306	14/18670	0.2451	0.4667	0.359	IMPA2/INPP5B/INPP1	3
BP	GO:0048266	behavioral response to pain	3/2306	14/18670	0.2451	0.4667	0.359	THBS1/P2RX3/CAPN2	3
BP	GO:0050862	positive regulation of T cell receptor signaling pathway	3/2306	14/18670	0.2451	0.4667	0.359	KCNN4/CYLD/ADA	3
BP	GO:0050930	induction of positive chemotaxis	3/2306	14/18670	0.2451	0.4667	0.359	VEGFA/PGF/FGF10	3
BP	GO:0051645	Golgi localization	3/2306	14/18670	0.2451	0.4667	0.359	HOOK3/ARHGAP21/CDC42	3
BP	GO:0051917	regulation of fibrinolysis	3/2306	14/18670	0.2451	0.4667	0.359	THBS1/SERPINE1/SERPINF2	3
BP	GO:0051938	L-glutamate import	3/2306	14/18670	0.2451	0.4667	0.359	SLC7A11/ARL6IP5/CLN8	3
BP	GO:0055064	chloride ion homeostasis	3/2306	14/18670	0.2451	0.4667	0.359	CA12/SLC12A2/ABCC2	3
BP	GO:0060009	Sertoli cell development	3/2306	14/18670	0.2451	0.4667	0.359	ICAM1/RAB13/ARID4A	3
BP	GO:0060211	regulation of nuclear-transcribed mRNA poly(A) tail shortening	3/2306	14/18670	0.2451	0.4667	0.359	ZFP36/PABPC1/BTG2	3
BP	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway	3/2306	14/18670	0.2451	0.4667	0.359	GHR/STAT6/STAT3	3
BP	GO:0060452	positive regulation of cardiac muscle contraction	3/2306	14/18670	0.2451	0.4667	0.359	RGS2/MIR1-2/NPPA	3
BP	GO:0070672	response to interleukin-15	3/2306	14/18670	0.2451	0.4667	0.359	IL15RA/IL15/STAT3	3
BP	GO:0071941	nitrogen cycle metabolic process	3/2306	14/18670	0.2451	0.4667	0.359	ASS1/CEBPA/CPS1	3
BP	GO:0072216	positive regulation of metanephros development	3/2306	14/18670	0.2451	0.4667	0.359	LIF/BASP1/PDGFRB	3
BP	GO:0072567	chemokine (C-X-C motif) ligand 2 production	3/2306	14/18670	0.2451	0.4667	0.359	KLF4/MBP/TNF	3
BP	GO:0099171	presynaptic modulation of chemical synaptic transmission	3/2306	14/18670	0.2451	0.4667	0.359	RPL22/CDK5/SYT1	3
BP	GO:0106070	regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	3/2306	14/18670	0.2451	0.4667	0.359	PRKCA/ARRDC3/MRAP2	3
BP	GO:1900452	regulation of long-term synaptic depression	3/2306	14/18670	0.2451	0.4667	0.359	ADORA1/KCNB1/DGKI	3
BP	GO:1901070	guanosine-containing compound biosynthetic process	3/2306	14/18670	0.2451	0.4667	0.359	NME5/IMPDH2/GUK1	3
BP	GO:1901626	regulation of postsynaptic membrane organization	3/2306	14/18670	0.2451	0.4667	0.359	SLC7A11/SSH1/CRKL	3
BP	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	3/2306	14/18670	0.2451	0.4667	0.359	THBS1/STK4/PMAIP1	3
BP	GO:1903624	regulation of DNA catabolic process	3/2306	14/18670	0.2451	0.4667	0.359	IL6/RGN/ST20	3
BP	GO:0031571	mitotic G1 DNA damage checkpoint	10/2306	63/18670	0.2462	0.4683	0.3603	PLK2/RPA2/CCND1/PRMT1/CARM1/BTG2/ARID3A/CNOT8/CDKN1A/TFDP1	10
BP	GO:0034394	protein localization to cell surface	10/2306	63/18670	0.2462	0.4683	0.3603	GPD1L/VCL/STX3/MAP1A/ARF6/TNF/PIGK/TOR1A/FGF10/PICALM	10
BP	GO:0044819	mitotic G1/S transition checkpoint	10/2306	63/18670	0.2462	0.4683	0.3603	PLK2/RPA2/CCND1/PRMT1/CARM1/BTG2/ARID3A/CNOT8/CDKN1A/TFDP1	10
BP	GO:0050772	positive regulation of axonogenesis	13/2306	85/18670	0.2468	0.4694	0.3611	NTN1/ZFYVE27/DBN1/VEGFA/PAK1/SLIT2/BMPR2/RUFY3/SEMA4D/ROBO1/PLXND1/GDI1/CDH4	13
BP	GO:1903305	regulation of regulated secretory pathway	23/2306	160/18670	0.2491	0.4734	0.3643	ADORA2A/IL4R/HLA-F/BACE1/SNX4/RAB3GAP1/CDK5/KCNB1/RAB3A/SYT4/ARF1/PREPL/PFN2/DGKI/ATP2A2/STXBP1/SYT1/GRIN3A/VAMP7/NPPA/NAPB/DVL1/ADRA2A	23
BP	GO:0007215	glutamate receptor signaling pathway	15/2306	100/18670	0.2494	0.4736	0.3644	CCL2/PPARGC1A/DAPK1/FYN/GRIA3/MEF2C/DAGLA/KCNB1/DLG4/DAGLB/GRM2/GRIK4/GRIN3A/CNIH2/HOMER2	15
BP	GO:0022600	digestive system process	15/2306	100/18670	0.2494	0.4736	0.3644	KCNN4/ACO1/NPR3/TYMP/LIMA1/UGCG/OXTR/NPC1L1/VDR/ZNF830/FGF10/SERPINA3/ADRA2A/TFF1/SNX10	15
BP	GO:0060079	excitatory postsynaptic potential	15/2306	100/18670	0.2494	0.4736	0.3644	ADORA2A/SSH1/RAB3GAP1/MEF2C/CDK5/RGS4/ADORA1/DGKI/P2RX3/CHRNB1/DLG4/PPP3CA/DVL1/P2RX7/TMEM108	15
BP	GO:0031295	T cell costimulation	9/2306	56/18670	0.2502	0.4749	0.3654	MAP3K8/TNFRSF14/PDCD1LG2/TNFSF13B/PAK1/FYN/EFNB1/PTPN11/CDC42	9
BP	GO:1903078	positive regulation of protein localization to plasma membrane	9/2306	56/18670	0.2502	0.4749	0.3654	SQSTM1/NKD2/STX3/RAB11FIP2/CLIP3/STAC/ARF6/TNF/RER1	9
BP	GO:0042157	lipoprotein metabolic process	19/2306	130/18670	0.2506	0.4755	0.3659	ABCA1/UGCG/PIGV/WIPI1/RAB3GAP1/PPT1/LIPG/NPC1L1/APOL6/ZDHHC16/CLIP3/ATG7/MPPE1/PIGK/WDR45/PIGS/ZDHHC18/APOL4/NMT2	19
BP	GO:0021954	central nervous system neuron development	12/2306	78/18670	0.2518	0.4777	0.3675	SLIT2/LHX8/ROBO1/CDK5/WNT5A/BTG2/ADARB1/UBB/MYCBP2/DCLK2/CRKL/NFIB	12
BP	GO:0050679	positive regulation of epithelial cell proliferation	29/2306	206/18670	0.2528	0.4793	0.3688	BMP2/TNFAIP3/CCL5/FGF2/PRKCA/VEGFA/CFLAR/BMP4/LAMB1/BMPR2/CCND1/ITGA4/CYBA/TCF7L2/TGFA/HAS2/SIRT1/WNT5A/TP63/PGF/OSR2/RTN4/FGF10/IGF1/AGGF1/STAT3/OSR1/FZD7/SIRT6	29
BP	GO:0032984	protein-containing complex disassembly	45/2306	329/18670	0.253	0.4797	0.3691	CHMP1B/MRPS24/GABARAPL1/MID1/FZD1/LIMA1/SET/IRAK3/MRPS35/SMARCD3/RDX/MRPS9/DSTN/FZD2/STMN3/DENR/PLEKHH2/MRPL1/MAP1A/CAPZA2/MRPS18C/MICAL3/EPS8/GSN/TNF/MRPL24/MTIF3/CHMP5/ARID1A/PBRM1/PDXP/SMARCE1/MCOLN1/MRPL14/TMOD2/NAPB/MRPL3/MRPL13/MRPL17/DVL1/DVL2/TAOK1/MRPL48/MID1IP1/CAMSAP1	45
BP	GO:0003044	regulation of systemic arterial blood pressure mediated by a chemical signal	8/2306	49/18670	0.2539	0.4807	0.3698	SOD2/PDE4D/CYBA/OXTR/EDN1/F2R/ADRB3/SERPINF2	8
BP	GO:0003254	regulation of membrane depolarization	8/2306	49/18670	0.2539	0.4807	0.3698	FHL1/GPD1L/CAMK2D/ANK3/ABCD1/HCN4/MIR1-2/P2RX7	8
BP	GO:0008347	glial cell migration	8/2306	49/18670	0.2539	0.4807	0.3698	CCL2/CSF1/LAMB1/CCL3/TGFB2/CDK5/RTN4/CRKL	8
BP	GO:0051205	protein insertion into membrane	8/2306	49/18670	0.2539	0.4807	0.3698	BID/PPP3CC/TRAM2/PMAIP1/RTP4/TP63/YWHAH/TFDP1	8
BP	GO:0090316	positive regulation of intracellular protein transport	22/2306	153/18670	0.2546	0.4807	0.3698	ZC3H12A/PTGS2/IL1B/PDCD5/PAK1/FYN/ANK3/RUFY3/PIK3R2/UBR5/TCF7L2/ARIH2/RHOU/CEP290/CDK5/KCNB1/BAP1/PRKCD/CTDSPL2/GAS6/TMEM30B/CHP2	22
BP	GO:0006476	protein deacetylation	14/2306	93/18670	0.2548	0.4807	0.3698	VEGFA/SAP30/CAMK2D/MORF4L2/TBL1Y/SIRT1/AKAP8/PER1/MSL3/SIN3B/TBL1XR1/SMARCAD1/TADA3/SIRT6	14
BP	GO:0099565	chemical synaptic transmission, postsynaptic	16/2306	108/18670	0.2561	0.4807	0.3698	ADORA2A/SSH1/RAB3GAP1/MEF2C/CDK5/RGS4/ADORA1/ABAT/DGKI/P2RX3/CHRNB1/DLG4/PPP3CA/DVL1/P2RX7/TMEM108	16
BP	GO:0002438	acute inflammatory response to antigenic stimulus	4/2306	21/18670	0.2562	0.4807	0.3698	ICAM1/C3/HLA-E/GATA3	4
BP	GO:0006293	nucleotide-excision repair, preincision complex stabilization	4/2306	21/18670	0.2562	0.4807	0.3698	RPA2/ERCC2/DDB2/GTF2H5	4
BP	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion	4/2306	21/18670	0.2562	0.4807	0.3698	RPA2/ERCC2/DDB2/GTF2H5	4
BP	GO:0006622	protein targeting to lysosome	4/2306	21/18670	0.2562	0.4807	0.3698	GNPTAB/GCC2/M6PR/NEDD4	4
BP	GO:0007035	vacuolar acidification	4/2306	21/18670	0.2562	0.4807	0.3698	ATP6V0E2/PPT1/DMXL1/ROGDI	4
BP	GO:0017000	antibiotic biosynthetic process	4/2306	21/18670	0.2562	0.4807	0.3698	FYN/CYBA/CYP1A2/STAT3	4
BP	GO:0031290	retinal ganglion cell axon guidance	4/2306	21/18670	0.2562	0.4807	0.3698	VEGFA/SLIT2/PTPRM/SEMA4F	4
BP	GO:0032332	positive regulation of chondrocyte differentiation	4/2306	21/18670	0.2562	0.4807	0.3698	HOXA11/SOX5/GDF5/GDF6	4
BP	GO:0032674	regulation of interleukin-5 production	4/2306	21/18670	0.2562	0.4807	0.3698	IL33/PDE4D/IL17RB/GATA3	4
BP	GO:0035162	embryonic hemopoiesis	4/2306	21/18670	0.2562	0.4807	0.3698	KIT/VEGFA/STK4/GATA3	4
BP	GO:0036150	phosphatidylserine acyl-chain remodeling	4/2306	21/18670	0.2562	0.4807	0.3698	OSBPL10/PLA2G4A/PLA2G12A/OSBPL5	4
BP	GO:0042438	melanin biosynthetic process	4/2306	21/18670	0.2562	0.4807	0.3698	SLC7A11/MC1R/TRPC1/WNT5A	4
BP	GO:0042749	regulation of circadian sleep/wake cycle	4/2306	21/18670	0.2562	0.4807	0.3698	CSF2/ADORA2A/ADA/ADORA1	4
BP	GO:0043984	histone H4-K16 acetylation	4/2306	21/18670	0.2562	0.4807	0.3698	AUTS2/SIRT1/MSL1/MSL3	4
BP	GO:0046386	deoxyribose phosphate catabolic process	4/2306	21/18670	0.2562	0.4807	0.3698	NUDT18/ADA/NUDT1/MBD4	4
BP	GO:0046827	positive regulation of protein export from nucleus	4/2306	21/18670	0.2562	0.4807	0.3698	IL1B/TCF7L2/CTDSPL2/GAS6	4
BP	GO:0060044	negative regulation of cardiac muscle cell proliferation	4/2306	21/18670	0.2562	0.4807	0.3698	MEIS1/JARID2/MIR1-2/MIR199A2	4
BP	GO:0060972	left/right pattern formation	4/2306	21/18670	0.2562	0.4807	0.3698	AHI1/CITED2/SETDB2/MNS1	4
BP	GO:0061339	establishment or maintenance of monopolar cell polarity	4/2306	21/18670	0.2562	0.4807	0.3698	FSCN1/WNT5A/PTK7/CDC42	4
BP	GO:0072010	glomerular epithelium development	4/2306	21/18670	0.2562	0.4807	0.3698	BASP1/BMP4/MYO1E/PODXL	4
BP	GO:0140131	positive regulation of lymphocyte chemotaxis	4/2306	21/18670	0.2562	0.4807	0.3698	CCL5/CCL7/CCL3/WNT5A	4
BP	GO:1902307	positive regulation of sodium ion transmembrane transport	4/2306	21/18670	0.2562	0.4807	0.3698	CNKSR3/ANK3/ARF1/ACTN4	4
BP	GO:1902473	regulation of protein localization to synapse	4/2306	21/18670	0.2562	0.4807	0.3698	GPC4/WNT5A/DVL1/GRIPAP1	4
BP	GO:1902884	positive regulation of response to oxidative stress	4/2306	21/18670	0.2562	0.4807	0.3698	MMP3/ACOX2/RGN/TNF	4
BP	GO:1904753	negative regulation of vascular associated smooth muscle cell migration	4/2306	21/18670	0.2562	0.4807	0.3698	MEF2C/MIR137/MIR214/MIR218-1	4
BP	GO:1904886	beta-catenin destruction complex disassembly	4/2306	21/18670	0.2562	0.4807	0.3698	FZD1/FZD2/DVL1/DVL2	4
BP	GO:2000269	regulation of fibroblast apoptotic process	4/2306	21/18670	0.2562	0.4807	0.3698	BID/API5/TP63/GAS6	4
BP	GO:0006654	phosphatidic acid biosynthetic process	7/2306	42/18670	0.257	0.4808	0.3699	PLD1/GPD1L/PLA2G4A/PLA2G12A/ABHD5/GPAM/LCLAT1	7
BP	GO:0021983	pituitary gland development	7/2306	42/18670	0.257	0.4808	0.3699	BMP2/PITX1/BMP4/ETS1/SRD5A1/WNT5A/FGF10	7
BP	GO:0030517	negative regulation of axon extension	7/2306	42/18670	0.257	0.4808	0.3699	NTN1/SEMA4D/IFRD1/CDK5/WNT5A/RTN4/SEMA4F	7
BP	GO:0032958	inositol phosphate biosynthetic process	7/2306	42/18670	0.257	0.4808	0.3699	PLCD3/FGF2/PLCE1/PLCD1/PLCB4/ITPKA/IP6K3	7
BP	GO:0033003	regulation of mast cell activation	7/2306	42/18670	0.257	0.4808	0.3699	PLSCR1/IL4R/SNX4/CNR2/STXBP1/VAMP7/NPPA	7
BP	GO:0042181	ketone biosynthetic process	7/2306	42/18670	0.257	0.4808	0.3699	BMP2/PPARGC1A/COQ10B/PDSS2/UBIAD1/COQ3/CYP19A1	7
BP	GO:0001936	regulation of endothelial cell proliferation	25/2306	176/18670	0.257	0.4808	0.3699	BMP2/CCL2/FGF2/PRKCA/STAT1/VEGFA/BMP4/NR2F2/BMPR2/ITGA4/CYBA/THBS1/MEF2C/SIRT1/WNT5A/SULF1/TNF/PGF/SPARC/PTPRM/PPARG/AGGF1/STAT3/SIRT6/ATOH8	25
BP	GO:0050866	negative regulation of cell activation	28/2306	199/18670	0.2583	0.4808	0.3699	ZC3H12A/TNFAIP3/ID2/ADORA2A/IRF1/CEBPB/C1QTNF1/TNFRSF14/PDCD1LG2/IDO1/BMP4/IL4R/SOCS1/HLA-F/LRRC32/UBASH3B/MAD1L1/CYGB/DUSP3/AXL/ABAT/HAVCR2/CNR2/PRKCD/HLA-G/SDC4/PDE5A/CBFB	28
BP	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic	6/2306	35/18670	0.2591	0.4808	0.3699	TTC37/EXOSC6/DCP1A/CNOT8/LSM6/PATL1	6
BP	GO:0003203	endocardial cushion morphogenesis	6/2306	35/18670	0.2591	0.4808	0.3699	BMP2/MSX2/TGFB2/SNAI2/ROBO1/ENG	6
BP	GO:0014904	myotube cell development	6/2306	35/18670	0.2591	0.4808	0.3699	SIX1/SMYD3/BIN3/PPP3CA/IGF1/DNER	6
BP	GO:0032735	positive regulation of interleukin-12 production	6/2306	35/18670	0.2591	0.4808	0.3699	RIPK2/IRF1/IDO1/CD40/TLR3/HLA-G	6
BP	GO:0042455	ribonucleoside biosynthetic process	6/2306	35/18670	0.2591	0.4808	0.3699	ADA/NME5/IMPDH2/GUK1/MTAP/PRTFDC1	6
BP	GO:0060251	regulation of glial cell proliferation	6/2306	35/18670	0.2591	0.4808	0.3699	IL6/IL1B/MYB/ASCL2/TNF/MIR125B1	6
BP	GO:0070873	regulation of glycogen metabolic process	6/2306	35/18670	0.2591	0.4808	0.3699	PPP1R3F/IRS1/DYRK2/PHLDA2/ENPP1/IGF1	6
BP	GO:0071312	cellular response to alkaloid	6/2306	35/18670	0.2591	0.4808	0.3699	ICAM1/PPARGC1A/PPP1R9B/ATG7/BCL2L1/CASP7	6
BP	GO:0098801	regulation of renal system process	6/2306	35/18670	0.2591	0.4808	0.3699	ADORA2A/CYBA/EDN1/F2R/ADORA1/GAS6	6
BP	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	6/2306	35/18670	0.2591	0.4808	0.3699	BID/PPP3CC/PMAIP1/TP63/YWHAH/TFDP1	6
BP	GO:1901385	regulation of voltage-gated calcium channel activity	6/2306	35/18670	0.2591	0.4808	0.3699	RRAD/GEM/STAC/PDE4B/NPPA/SRI	6
BP	GO:0001773	myeloid dendritic cell activation	5/2306	28/18670	0.2594	0.4808	0.3699	CSF2/RELB/BATF3/HAVCR2/UBD	5
BP	GO:0001958	endochondral ossification	5/2306	28/18670	0.2594	0.4808	0.3699	NAB1/BMP4/COL1A1/CSGALNACT1/MEF2C	5
BP	GO:0002691	regulation of cellular extravasation	5/2306	28/18670	0.2594	0.4808	0.3699	ICAM1/FADD/ITGA4/PDGFD/ADAM8	5
BP	GO:0006760	folic acid-containing compound metabolic process	5/2306	28/18670	0.2594	0.4808	0.3699	MTHFD2L/GCH1/MTHFD2/SLC19A1/ALDH1L2	5
BP	GO:0007205	protein kinase C-activating G protein-coupled receptor signaling pathway	5/2306	28/18670	0.2594	0.4808	0.3699	BDKRB1/ADORA2A/EDN1/F2R/DGKI	5
BP	GO:0008045	motor neuron axon guidance	5/2306	28/18670	0.2594	0.4808	0.3699	NTN1/SLIT2/CHN1/CDK5/MYCBP2	5
BP	GO:0009065	glutamine family amino acid catabolic process	5/2306	28/18670	0.2594	0.4808	0.3699	DDAH1/GLS/FAH/GLUD1/DDAH2	5
BP	GO:0010894	negative regulation of steroid biosynthetic process	5/2306	28/18670	0.2594	0.4808	0.3699	BMP2/NFKB1/INSIG2/CYP27B1/SNAI2	5
BP	GO:0036075	replacement ossification	5/2306	28/18670	0.2594	0.4808	0.3699	NAB1/BMP4/COL1A1/CSGALNACT1/MEF2C	5
BP	GO:0042730	fibrinolysis	5/2306	28/18670	0.2594	0.4808	0.3699	SERPINB2/PLAU/THBS1/SERPINE1/SERPINF2	5
BP	GO:0045408	regulation of interleukin-6 biosynthetic process	5/2306	28/18670	0.2594	0.4808	0.3699	IL1B/CEBPB/EREG/TNF/STAT3	5
BP	GO:0045686	negative regulation of glial cell differentiation	5/2306	28/18670	0.2594	0.4808	0.3699	GPR37L1/ID2/DAAM2/HES5/DUSP10	5
BP	GO:0048520	positive regulation of behavior	5/2306	28/18670	0.2594	0.4808	0.3699	ADORA2A/NPAS2/SGIP1/MEF2C/VPS35	5
BP	GO:0051123	RNA polymerase II preinitiation complex assembly	5/2306	28/18670	0.2594	0.4808	0.3699	DR1/CAND1/THRA/TAF7L/TAF6L	5
BP	GO:0060260	regulation of transcription initiation from RNA polymerase II promoter	5/2306	28/18670	0.2594	0.4808	0.3699	DR1/CAND1/THRA/SUB1/ZNF451	5
BP	GO:0061615	glycolytic process through fructose-6-phosphate	5/2306	28/18670	0.2594	0.4808	0.3699	HK2/ENO2/ADPGK/PGM2L1/ALDOC	5
BP	GO:0061620	glycolytic process through glucose-6-phosphate	5/2306	28/18670	0.2594	0.4808	0.3699	HK2/ENO2/ADPGK/PGM2L1/ALDOC	5
BP	GO:0085029	extracellular matrix assembly	5/2306	28/18670	0.2594	0.4808	0.3699	HAS2/HAS1/HAS3/COL1A2/GAS6	5
BP	GO:0090344	negative regulation of cell aging	5/2306	28/18670	0.2594	0.4808	0.3699	NAMPT/CDK6/PLK2/SIRT1/ABL1	5
BP	GO:1904994	regulation of leukocyte adhesion to vascular endothelial cell	5/2306	28/18670	0.2594	0.4808	0.3699	ICAM1/ETS1/KLF4/ITGA4/TNF	5
BP	GO:1905063	regulation of vascular smooth muscle cell differentiation	5/2306	28/18670	0.2594	0.4808	0.3699	SOD2/KIT/MIR1-2/MIR125B1/ENG	5
BP	GO:0006400	tRNA modification	13/2306	86/18670	0.2604	0.4824	0.3711	ELP4/THADA/QTRT1/METTL6/SEPHS1/PUS10/NSUN3/PUS7/ALKBH8/LCMT2/CDKAL1/TRMU/OSGEPL1	13
BP	GO:0060291	long-term synaptic potentiation	13/2306	86/18670	0.2604	0.4824	0.3711	ADORA2A/SQSTM1/GIP/PLK2/STX3/EIF2AK4/ADORA1/SNAP47/STAU1/TSHZ3/NPTN/ABL1/YTHDF1	13
BP	GO:0006733	oxidoreduction coenzyme metabolic process	29/2306	207/18670	0.2615	0.4841	0.3724	NAMPT/PTGS2/PPARGC1A/SLC2A6/GPD1L/KYNU/IDO1/HK2/ENO2/ADPGK/COQ10B/NUP133/IDH1/PGM2L1/NNMT/PDSS2/UBIAD1/PARP9/COQ3/LDHB/PDHB/ME1/PGAM4/NUP35/IGF1/STAT3/ALDOC/P2RX7/SIRT6	29
BP	GO:0034284	response to monosaccharide	29/2306	207/18670	0.2615	0.4841	0.3724	ICAM1/NAMPT/PTGS2/ENSA/ERN1/PPARGC1A/GJD3/GIP/CYBA/THBS1/TCF7L2/RAB11FIP2/ITGA2/LRP5/ATG7/KCNB1/SESN2/DYNLL1/SPARC/BRSK2/EIF2B5/EIF2B4/GYS2/PPP3CA/PDK3/GAS6/SRI/RMI1/ADRA2A	29
BP	GO:0000018	regulation of DNA recombination	15/2306	101/18670	0.2619	0.4846	0.3728	IL7R/RPA2/CD40/EXOSC6/ERCC2/CLCF1/PPP4C/STAT6/MMS19/MAGEF1/ACTR2/KPNA2/ZSCAN4/SMARCAD1/SIRT6	15
BP	GO:0035794	positive regulation of mitochondrial membrane permeability	10/2306	64/18670	0.2621	0.4846	0.3728	BID/PPP3CC/PPIF/PMAIP1/TP63/ACAA2/YWHAH/TMEM14A/TFDP1/EYA2	10
BP	GO:0044783	G1 DNA damage checkpoint	10/2306	64/18670	0.2621	0.4846	0.3728	PLK2/RPA2/CCND1/PRMT1/CARM1/BTG2/ARID3A/CNOT8/CDKN1A/TFDP1	10
BP	GO:0050922	negative regulation of chemotaxis	10/2306	64/18670	0.2621	0.4846	0.3728	CCL2/SLIT2/THBS1/SEMA4D/DUSP3/ROBO1/WNT5A/SLAMF8/SEMA4F/CYP19A1	10
BP	GO:0018394	peptidyl-lysine acetylation	24/2306	169/18670	0.2628	0.4859	0.3738	IL1B/LIF/BRPF3/PPARGC1A/AUTS2/SET/DR1/KAT2B/SNAI2/MORF4L2/RPS6KA4/YEATS2/SIRT1/MSL1/GATA3/IWS1/SETD5/TAF6L/PER1/GTF3C4/MSL3/ZNF451/TADA3/PHF10	24
BP	GO:0070085	glycosylation	37/2306	269/18670	0.2658	0.4913	0.378	GFPT2/ST3GAL1/ST8SIA1/MAN1A1/B4GALT3/PIGV/GALNT10/MAN1C1/A4GALT/IL15/TET1/GXYLT1/SERP2/MOGS/POMGNT1/RAMP1/PGM3/GALNT5/MGAT1/MGAT2/GCNT1/TET3/C1GALT1/EXT1/ST3GAL3/ALG3/GALNT4/DAD1/DPY19L4/MUC15/MUC17/ALG13/GALNT11/GALNT1/SLC35C1/TMEM165/ST3GAL4	37
BP	GO:0006720	isoprenoid metabolic process	20/2306	139/18670	0.2665	0.4923	0.3788	AKR1B1/ALDH1A3/CYP27C1/GPC4/RDH10/RDH8/HSPG2/DHRS3/SRD5A1/ADH5/SDC2/CYP1A2/PDSS2/SDC4/PECR/RDH13/ADH1C/IDI1/CYP2C19/CYP2S1	20
BP	GO:0002066	columnar/cuboidal epithelial cell development	9/2306	57/18670	0.2672	0.493	0.3793	CDK6/BMP4/ARNTL/YIPF6/WNT5A/C1GALT1/PRDM1/CDKN1A/ROS1	9
BP	GO:0018208	peptidyl-proline modification	9/2306	57/18670	0.2672	0.493	0.3793	PPIF/P4HA2/EGLN1/PPIA/PPIL2/FKBP3/PPIL4/FKBP1A/NKTR	9
BP	GO:0031294	lymphocyte costimulation	9/2306	57/18670	0.2672	0.493	0.3793	MAP3K8/TNFRSF14/PDCD1LG2/TNFSF13B/PAK1/FYN/EFNB1/PTPN11/CDC42	9
BP	GO:0043525	positive regulation of neuron apoptotic process	9/2306	57/18670	0.2672	0.493	0.3793	ITGA1/MYB/BACE1/CCL3/UBE2M/TGFB2/CDK5/TNF/MIR125B1	9
BP	GO:0019218	regulation of steroid metabolic process	18/2306	124/18670	0.2677	0.4938	0.3799	BMP2/IL1B/NFKB1/PPARGC1A/KIT/INSIG2/ACACB/SCD/DDX20/CYP27B1/TM7SF2/ACACA/SNAI2/VDR/SIRT1/TNF/GPAM/IDI1	18
BP	GO:0006029	proteoglycan metabolic process	14/2306	94/18670	0.2679	0.494	0.3801	BMP2/BMPR2/VCAN/CHST7/SULF2/TCF7L2/CYTL1/CSGALNACT1/CSGALNACT2/SULF1/CHST8/EXT1/HS2ST1/IGF1	14
BP	GO:0042158	lipoprotein biosynthetic process	14/2306	94/18670	0.2679	0.494	0.3801	ABCA1/UGCG/PIGV/WIPI1/RAB3GAP1/ZDHHC16/CLIP3/ATG7/MPPE1/PIGK/WDR45/PIGS/ZDHHC18/NMT2	14
BP	GO:0006289	nucleotide-excision repair	16/2306	109/18670	0.2683	0.4943	0.3803	RAD23B/RPA2/SLC30A9/ERCC2/DDB2/SIRT1/COPS4/RAD23A/ZNF830/MMS19/GTF2H5/UBB/MNAT1/RFC2/CDK7/NEIL3	16
BP	GO:0051261	protein depolymerization	16/2306	109/18670	0.2683	0.4943	0.3803	MID1/LIMA1/RDX/DSTN/STMN3/PLEKHH2/MAP1A/CAPZA2/MICAL3/EPS8/GSN/PDXP/TMOD2/TAOK1/MID1IP1/CAMSAP1	16
BP	GO:0009314	response to radiation	60/2306	448/18670	0.2688	0.4951	0.3809	ICAM1/NAMPT/PTGS2/VCAM1/CXCL10/ID2/CCL7/KIT/SLC7A11/KRT14/IL12A/REEP6/CALM1/CCND1/NET1/CDC25A/BACE1/CYBA/SCARA3/MAPK13/EIF2AK4/CRYAB/MC1R/RHOB/ERCC2/TP53INP1/DDB2/SNAI2/YAP1/POLB/BCL3/CEP250/CDK5/SIRT1/JUNB/BCL2L1/TXN/XRCC4/CACNA1F/PPM1D/ASNS/C9orf116/ATP8A2/GATA3/FEN1/NPTN/IVL/GTF2H5/NUCKS1/MBD4/PER1/RDH13/CDKN1A/SIK1/UBE4B/UIMC1/NEDD4/NMT2/ST20/NPHP1	60
BP	GO:0032272	negative regulation of protein polymerization	11/2306	72/18670	0.2721	0.5006	0.3852	SLIT2/MYADM/RDX/CLIP3/CAPZA2/PFN2/EPS8/GSN/PRKCD/MIR214/TMOD2	11
BP	GO:0061035	regulation of cartilage development	11/2306	72/18670	0.2721	0.5006	0.3852	BMP2/BMP4/BMPR2/HOXA11/PTHLH/SOX5/SNAI2/GDF5/CARM1/WNT5A/GDF6	11
BP	GO:0001706	endoderm formation	8/2306	50/18670	0.2722	0.5006	0.3852	LAMB1/ITGB5/ITGA4/COL5A2/GATA6/MMP9/SOX7/COL5A1	8
BP	GO:0014009	glial cell proliferation	8/2306	50/18670	0.2722	0.5006	0.3852	IL6/IL1B/IL33/CSF1/MYB/ASCL2/TNF/MIR125B1	8
BP	GO:0045104	intermediate filament cytoskeleton organization	8/2306	50/18670	0.2722	0.5006	0.3852	KRT14/KRT16/SYNM/KRT2/CLN8/ATP8A2/PRPH/TOR1A	8
BP	GO:0042552	myelination	19/2306	132/18670	0.2727	0.5015	0.3858	NAB1/TNFRSF1B/TYMP/ARHGEF10/JAM3/CNTNAP1/MBP/EPB41L3/ERCC2/LPAR1/MALL/ABCD1/HES5/UGT8/EIF2B5/EIF2B4/SBF2/TSPAN2/CMTM8	19
BP	GO:0006413	translational initiation	27/2306	193/18670	0.2732	0.5023	0.3864	CCL5/HSPB1/EIF4A2/PPP1R15A/RXRA/RPS3A/EIF2AK4/DENR/EIF4G3/DNAJC3/RPL7/RPL22/EIF1/EIF4A1/PABPC1/RPL37A/DHX29/EIF3E/TNF/MTIF3/EIF2B5/EIF2B4/RPL15/EIF2S2/YTHDF1/RPS18/EIF1B	27
BP	GO:0045844	positive regulation of striated muscle tissue development	13/2306	87/18670	0.2742	0.5038	0.3876	FGF2/BMP4/PIM1/EDN1/ARNTL/GATA6/YAP1/FLOT1/MEF2C/MIR19B2/MIR1-2/MIR199A2/IGF1	13
BP	GO:0048636	positive regulation of muscle organ development	13/2306	87/18670	0.2742	0.5038	0.3876	FGF2/BMP4/PIM1/EDN1/ARNTL/GATA6/YAP1/FLOT1/MEF2C/MIR19B2/MIR1-2/MIR199A2/IGF1	13
BP	GO:0098869	cellular oxidant detoxification	15/2306	102/18670	0.2746	0.5044	0.3881	SOD2/PTGS2/SESN1/GSTO1/GCH1/TP53INP1/CYGB/UBIAD1/RGN/SESN2/TXN/TNF/HBB/PTGS1/MGST2	15
BP	GO:0010977	negative regulation of neuron projection development	22/2306	155/18670	0.2751	0.5051	0.3886	NTN1/DENND5A/PLK2/SLIT2/RUFY3/DPYSL3/SEMA4D/LPAR1/CARM1/IFRD1/CDK5/WNT5A/ARF6/YWHAH/GDI1/ASAP1/CRMP1/RTN4/PPP3CA/SEMA4F/MYLIP/NGEF	22
BP	GO:0000413	protein peptidyl-prolyl isomerization	7/2306	43/18670	0.277	0.5062	0.3895	PPIF/PPIA/PPIL2/FKBP3/PPIL4/FKBP1A/NKTR	7
BP	GO:0006692	prostanoid metabolic process	7/2306	43/18670	0.277	0.5062	0.3895	PTGS2/IL1B/PTGES/EDN1/SIRT1/PTGS1/CYP2S1	7
BP	GO:0006693	prostaglandin metabolic process	7/2306	43/18670	0.277	0.5062	0.3895	PTGS2/IL1B/PTGES/EDN1/SIRT1/PTGS1/CYP2S1	7
BP	GO:0006775	fat-soluble vitamin metabolic process	7/2306	43/18670	0.277	0.5062	0.3895	IL1B/NFKB1/CYP27B1/SNAI2/UBIAD1/VDR/TNF	7
BP	GO:0032924	activin receptor signaling pathway	7/2306	43/18670	0.277	0.5062	0.3895	CITED2/BMPR2/INHBB/FKBP1A/FST/FGF10/GDF6	7
BP	GO:0038202	TORC1 signaling	7/2306	43/18670	0.277	0.5062	0.3895	SIK3/SESN1/FNIP2/FNIP1/SESN3/SESN2/KPTN	7
BP	GO:0045687	positive regulation of glial cell differentiation	7/2306	43/18670	0.277	0.5062	0.3895	BMP2/LIF/ID2/TNFRSF1B/IL6ST/CLCF1/PPARG	7
BP	GO:0046460	neutral lipid biosynthetic process	7/2306	43/18670	0.277	0.5062	0.3895	GK/LPIN1/PLCE1/C3/RGN/GPAM/SIK1	7
BP	GO:0046463	acylglycerol biosynthetic process	7/2306	43/18670	0.277	0.5062	0.3895	GK/LPIN1/PLCE1/C3/RGN/GPAM/SIK1	7
BP	GO:0046473	phosphatidic acid metabolic process	7/2306	43/18670	0.277	0.5062	0.3895	PLD1/GPD1L/PLA2G4A/PLA2G12A/ABHD5/GPAM/LCLAT1	7
BP	GO:0002440	production of molecular mediator of immune response	39/2306	286/18670	0.2777	0.5062	0.3895	IL6/IL1B/IL33/KIT/IL7R/TNFRSF14/RSAD2/TNFRSF1B/TNFSF13B/HLA-E/IL12A/IL18R1/IL4R/POU2F2/HLA-F/CD40/IRAK3/DNAJB9/DDX58/TRAF3IP2/EXOSC6/TGFB2/CLCF1/STAT6/POLB/SIRT1/WNT5A/TRAF2/XRCC4/TNF/TLR3/TRIM6/GATA3/HLA-G/HLA-DQB1/BCL10/GAS6/TICAM1/SASH3	39
BP	GO:0009247	glycolipid biosynthetic process	10/2306	65/18670	0.2782	0.5062	0.3895	ST8SIA1/B4GALT3/UGCG/PIGV/A4GALT/UGT8/MPPE1/PIGK/PIGS/ST3GAL4	10
BP	GO:0045739	positive regulation of DNA repair	10/2306	65/18670	0.2782	0.5062	0.3895	NPAS2/FMN2/PARP9/SIRT1/MMS19/SETMAR/ACTR2/FGF10/UIMC1/EYA2	10
BP	GO:0051148	negative regulation of muscle cell differentiation	10/2306	65/18670	0.2782	0.5062	0.3895	BMP2/CXCL10/EREG/CFLAR/PAK1/RGS2/RGS4/MIR199A2/FZD7/FOXO4	10
BP	GO:0017148	negative regulation of translation	29/2306	209/18670	0.2792	0.5062	0.3895	ZC3H12A/DAPK1/CAPRIN1/ROCK1/MOV10/FTO/ENC1/ZFP36/EIF2AK4/ZFP36L2/PRG3/RGS2/MIR19B2/BTG2/SAMD4B/SESN2/EIF3E/PUS7/MIR1-2/MIR125B1/CNOT8/MIR298/SYNCRIP/ROCK2/FXR2/ZNF540/MRPL13/MIR218-1/STAT3	29
BP	GO:0006491	N-glycan processing	3/2306	15/18670	0.2804	0.5062	0.3895	MAN1A1/MAN1C1/GNPTAB	3
BP	GO:0006646	phosphatidylethanolamine biosynthetic process	3/2306	15/18670	0.2804	0.5062	0.3895	LPIN1/PISD/CHKB	3
BP	GO:0007351	tripartite regional subdivision	3/2306	15/18670	0.2804	0.5062	0.3895	BASP1/WNT5A/TBX3	3
BP	GO:0007512	adult heart development	3/2306	15/18670	0.2804	0.5062	0.3895	MYH6/MNAT1/MYH10	3
BP	GO:0008595	anterior/posterior axis specification, embryo	3/2306	15/18670	0.2804	0.5062	0.3895	BASP1/WNT5A/TBX3	3
BP	GO:0009263	deoxyribonucleotide biosynthetic process	3/2306	15/18670	0.2804	0.5062	0.3895	CMPK2/CDADC1/GUK1	3
BP	GO:0009415	response to water	3/2306	15/18670	0.2804	0.5062	0.3895	AKR1B1/PKD2/LRP11	3
BP	GO:0010561	negative regulation of glycoprotein biosynthetic process	3/2306	15/18670	0.2804	0.5062	0.3895	BACE2/HBEGF/ACOT8	3
BP	GO:0015671	oxygen transport	3/2306	15/18670	0.2804	0.5062	0.3895	CYGB/NGB/HBB	3
BP	GO:0018158	protein oxidation	3/2306	15/18670	0.2804	0.5062	0.3895	LOXL4/LOXL1/CHCHD4	3
BP	GO:0018216	peptidyl-arginine methylation	3/2306	15/18670	0.2804	0.5062	0.3895	PRMT1/CARM1/PRMT3	3
BP	GO:0030812	negative regulation of nucleotide catabolic process	3/2306	15/18670	0.2804	0.5062	0.3895	PPARGC1A/STAT3/SIRT6	3
BP	GO:0032239	regulation of nucleobase-containing compound transport	3/2306	15/18670	0.2804	0.5062	0.3895	CPSF6/ADORA1/IWS1	3
BP	GO:0033604	negative regulation of catecholamine secretion	3/2306	15/18670	0.2804	0.5062	0.3895	SYT4/ABAT/ADRA2A	3
BP	GO:0035067	negative regulation of histone acetylation	3/2306	15/18670	0.2804	0.5062	0.3895	SET/SIRT1/ZNF451	3
BP	GO:0036445	neuronal stem cell division	3/2306	15/18670	0.2804	0.5062	0.3895	SOX5/NUMBL/AKNA	3
BP	GO:0042976	activation of Janus kinase activity	3/2306	15/18670	0.2804	0.5062	0.3895	CCL5/SOCS1/GHR	3
BP	GO:0043508	negative regulation of JUN kinase activity	3/2306	15/18670	0.2804	0.5062	0.3895	DNAJA1/DUSP10/ZNF675	3
BP	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	3/2306	15/18670	0.2804	0.5062	0.3895	CD44/SNAI2/SIRT1	3
BP	GO:0043650	dicarboxylic acid biosynthetic process	3/2306	15/18670	0.2804	0.5062	0.3895	KYNU/GLS/GLUD1	3
BP	GO:0044406	adhesion of symbiont to host	3/2306	15/18670	0.2804	0.5062	0.3895	ICAM1/INHBB/GAS6	3
BP	GO:0045838	positive regulation of membrane potential	3/2306	15/18670	0.2804	0.5062	0.3895	BID/ANK3/PIAS3	3
BP	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly	3/2306	15/18670	0.2804	0.5062	0.3895	DR1/CAND1/THRA	3
BP	GO:0046838	phosphorylated carbohydrate dephosphorylation	3/2306	15/18670	0.2804	0.5062	0.3895	IMPA2/INPP5B/INPP1	3
BP	GO:0050651	dermatan sulfate proteoglycan biosynthetic process	3/2306	15/18670	0.2804	0.5062	0.3895	VCAN/CSGALNACT1/CSGALNACT2	3
BP	GO:0051127	positive regulation of actin nucleation	3/2306	15/18670	0.2804	0.5062	0.3895	FMN2/GSN/MAGEL2	3
BP	GO:0051198	negative regulation of coenzyme metabolic process	3/2306	15/18670	0.2804	0.5062	0.3895	PPARGC1A/STAT3/SIRT6	3
BP	GO:0055057	neuroblast division	3/2306	15/18670	0.2804	0.5062	0.3895	SOX5/NUMBL/AKNA	3
BP	GO:0055089	fatty acid homeostasis	3/2306	15/18670	0.2804	0.5062	0.3895	ABCD1/SIRT1/ADORA1	3
BP	GO:0060766	negative regulation of androgen receptor signaling pathway	3/2306	15/18670	0.2804	0.5062	0.3895	DAB2/SIRT1/NCOR2	3
BP	GO:0060841	venous blood vessel development	3/2306	15/18670	0.2804	0.5062	0.3895	VEGFA/BMPR2/ENG	3
BP	GO:0071474	cellular hyperosmotic response	3/2306	15/18670	0.2804	0.5062	0.3895	AKR1B1/SLC2A1/ERRFI1	3
BP	GO:0072283	metanephric renal vesicle morphogenesis	3/2306	15/18670	0.2804	0.5062	0.3895	LIF/STAT1/BMP4	3
BP	GO:0090192	regulation of glomerulus development	3/2306	15/18670	0.2804	0.5062	0.3895	CFLAR/BMP4/PDGFD	3
BP	GO:0090494	dopamine uptake	3/2306	15/18670	0.2804	0.5062	0.3895	SLC22A1/SLC22A3/TOR1A	3
BP	GO:0097428	protein maturation by iron-sulfur cluster transfer	3/2306	15/18670	0.2804	0.5062	0.3895	BOLA2/MMS19/MAGEF1	3
BP	GO:0099558	maintenance of synapse structure	3/2306	15/18670	0.2804	0.5062	0.3895	DCTN1/RAB3A/ARF6	3
BP	GO:1900037	regulation of cellular response to hypoxia	3/2306	15/18670	0.2804	0.5062	0.3895	DDAH1/HYOU1/ROCK2	3
BP	GO:1900119	positive regulation of execution phase of apoptosis	3/2306	15/18670	0.2804	0.5062	0.3895	ZC3H12A/IL6/ST20	3
BP	GO:1902514	regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	3/2306	15/18670	0.2804	0.5062	0.3895	CAMK2D/MIR1-2/NPPA	3
BP	GO:2000484	positive regulation of interleukin-8 secretion	3/2306	15/18670	0.2804	0.5062	0.3895	CD58/F2R/WNT5A	3
BP	GO:2001028	positive regulation of endothelial cell chemotaxis	3/2306	15/18670	0.2804	0.5062	0.3895	HSPB1/FGF2/VEGFA	3
BP	GO:0061387	regulation of extent of cell growth	16/2306	110/18670	0.2807	0.5066	0.3897	NTN1/ZFYVE27/DBN1/VEGFA/PAK1/BMPR2/RUFY3/SEMA4D/IFRD1/CDK5/WNT5A/GDI1/RTN4/ABL1/SEMA4F/CDH4	16
BP	GO:0070509	calcium ion import	12/2306	80/18670	0.2808	0.5066	0.3898	CCL2/PDGFRB/FYN/PKD2/CCL3/CDK5/SLC30A1/CACNA1F/CACNA1B/ATP2A2/SPINK1/ORAI1	12
BP	GO:0003091	renal water homeostasis	6/2306	36/18670	0.2812	0.5066	0.3898	AKR1B1/ADCY7/RAB11FIP2/ADCY9/HAS2/ADCY3	6
BP	GO:0006007	glucose catabolic process	6/2306	36/18670	0.2812	0.5066	0.3898	HK2/ENO2/ADPGK/PGM2L1/LRP5/ALDOC	6
BP	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	6/2306	36/18670	0.2812	0.5066	0.3898	IL1B/MYOF/VEGFA/FZD4/FGF10/NEDD4	6
BP	GO:0071392	cellular response to estradiol stimulus	6/2306	36/18670	0.2812	0.5066	0.3898	PPARGC1A/CFLAR/BCL2L2/MSX2/SRD5A1/ITGA2	6
BP	GO:0097242	amyloid-beta clearance	6/2306	36/18670	0.2812	0.5066	0.3898	IFNGR1/C3/ROCK1/CLTC/TNF/PICALM	6
BP	GO:0035107	appendage morphogenesis	21/2306	148/18670	0.2816	0.5071	0.3902	MBNL1/PITX1/RECK/BMP4/RDH10/HOXA11/MSX2/HOXA10/TGFB2/HOXD9/GDF5/GNA12/WNT5A/TP63/FBXW4/OSR2/RSPO2/HOXA9/FGF10/OSR1/TBX3	21
BP	GO:0035108	limb morphogenesis	21/2306	148/18670	0.2816	0.5071	0.3902	MBNL1/PITX1/RECK/BMP4/RDH10/HOXA11/MSX2/HOXA10/TGFB2/HOXD9/GDF5/GNA12/WNT5A/TP63/FBXW4/OSR2/RSPO2/HOXA9/FGF10/OSR1/TBX3	21
BP	GO:0000082	G1/S transition of mitotic cell cycle	38/2306	279/18670	0.2835	0.5084	0.3912	BID/PSME2/CCL2/ID2/CDK6/FHL1/PSME1/PLK2/RPA2/PIM2/LATS2/PKD2/CCND1/KLF4/CDC25A/PRMT1/RDX/GJC2/CARM1/RHOU/CDKN2C/PRIM2/E2F6/BTG2/MIR137/ARID3A/CNOT8/CDK2AP2/PPP3CA/MIR214/MAX/CTDSP2/CDKN1A/FGF10/MNAT1/TFDP1/MEPCE/CDK7	38
BP	GO:0005979	regulation of glycogen biosynthetic process	5/2306	29/18670	0.2843	0.5084	0.3912	PPP1R3F/IRS1/DYRK2/ENPP1/IGF1	5
BP	GO:0010800	positive regulation of peptidyl-threonine phosphorylation	5/2306	29/18670	0.2843	0.5084	0.3912	RIPK2/CALM1/WNT5A/CALM2/TRIM6	5
BP	GO:0010962	regulation of glucan biosynthetic process	5/2306	29/18670	0.2843	0.5084	0.3912	PPP1R3F/IRS1/DYRK2/ENPP1/IGF1	5
BP	GO:0021602	cranial nerve morphogenesis	5/2306	29/18670	0.2843	0.5084	0.3912	ATP8B1/MAFB/SIX1/HOXD3/ADARB1	5
BP	GO:0031114	regulation of microtubule depolymerization	5/2306	29/18670	0.2843	0.5084	0.3912	MID1/MAP1A/TAOK1/MID1IP1/CAMSAP1	5
BP	GO:0032232	negative regulation of actin filament bundle assembly	5/2306	29/18670	0.2843	0.5084	0.3912	PPFIA1/ARHGAP28/PHLDB2/TACSTD2/WASF2	5
BP	GO:0033014	tetrapyrrole biosynthetic process	5/2306	29/18670	0.2843	0.5084	0.3912	SLC11A2/NFE2L1/ALAS1/SLC25A39/SUCLA2	5
BP	GO:0060536	cartilage morphogenesis	5/2306	29/18670	0.2843	0.5084	0.3912	SCARA3/SNAI2/MEF2C/COL6A3/RSPO2	5
BP	GO:0060765	regulation of androgen receptor signaling pathway	5/2306	29/18670	0.2843	0.5084	0.3912	DAB2/RNF14/SIRT1/DDX5/NCOR2	5
BP	GO:0070723	response to cholesterol	5/2306	29/18670	0.2843	0.5084	0.3912	ABCA1/NFE2L1/CCL3/OSBPL7/GRAMD1A	5
BP	GO:0072606	interleukin-8 secretion	5/2306	29/18670	0.2843	0.5084	0.3912	CD58/F2R/WNT5A/ANXA4/MAPKBP1	5
BP	GO:0045665	negative regulation of neuron differentiation	31/2306	225/18670	0.2845	0.5084	0.3912	GPR37L1/ID2/NTN1/MEIS1/DENND5A/PLK2/SLIT2/IRX3/RUFY3/EIF2AK4/DPYSL3/DIXDC1/SEMA4D/LPAR1/CARM1/IFRD1/CDK5/WNT5A/ARF6/HES5/YWHAH/GDI1/ASAP1/CRMP1/RTN4/PPP3CA/ID3/SEMA4F/MIB1/MYLIP/NGEF	31
BP	GO:0019229	regulation of vasoconstriction	9/2306	58/18670	0.2845	0.5084	0.3912	ICAM1/PTGS2/BDKRB2/BMPR2/OXTR/EDN1/F2R/DOCK4/ADRA2A	9
BP	GO:0002097	tRNA wobble base modification	4/2306	22/18670	0.2851	0.5084	0.3912	ELP4/NSUN3/ALKBH8/TRMU	4
BP	GO:0006085	acetyl-CoA biosynthetic process	4/2306	22/18670	0.2851	0.5084	0.3912	ACAT1/PPCS/PDHB/PDK3	4
BP	GO:0006582	melanin metabolic process	4/2306	22/18670	0.2851	0.5084	0.3912	SLC7A11/MC1R/TRPC1/WNT5A	4
BP	GO:0006783	heme biosynthetic process	4/2306	22/18670	0.2851	0.5084	0.3912	SLC11A2/NFE2L1/ALAS1/SLC25A39	4
BP	GO:0010155	regulation of proton transport	4/2306	22/18670	0.2851	0.5084	0.3912	PPIF/COX17/NOX5/ACTN4	4
BP	GO:0021854	hypothalamus development	4/2306	22/18670	0.2851	0.5084	0.3912	ETS1/SRD5A1/RAB3GAP1/UBB	4
BP	GO:0030878	thyroid gland development	4/2306	22/18670	0.2851	0.5084	0.3912	SIX1/THRA/HOXD3/FGF10	4
BP	GO:0032634	interleukin-5 production	4/2306	22/18670	0.2851	0.5084	0.3912	IL33/PDE4D/IL17RB/GATA3	4
BP	GO:0032656	regulation of interleukin-13 production	4/2306	22/18670	0.2851	0.5084	0.3912	IL33/HLA-E/IL17RB/GATA3	4
BP	GO:0035584	calcium-mediated signaling using intracellular calcium source	4/2306	22/18670	0.2851	0.5084	0.3912	CCL20/VCAM1/PTGFR/HOMER2	4
BP	GO:0035929	steroid hormone secretion	4/2306	22/18670	0.2851	0.5084	0.3912	C1QTNF1/NKX3-1/FZD4/PTPN11	4
BP	GO:0045624	positive regulation of T-helper cell differentiation	4/2306	22/18670	0.2851	0.5084	0.3912	NFKBIZ/RIPK2/MYB/IL4R	4
BP	GO:0045663	positive regulation of myoblast differentiation	4/2306	22/18670	0.2851	0.5084	0.3912	CXCL9/MEF2C/AKIRIN1/RANBP3L	4
BP	GO:0046339	diacylglycerol metabolic process	4/2306	22/18670	0.2851	0.5084	0.3912	PLCE1/DAGLA/DGKI/DAGLB	4
BP	GO:0060390	regulation of SMAD protein signal transduction	4/2306	22/18670	0.2851	0.5084	0.3912	DAB2/BMP4/WWTR1/GDF5	4
BP	GO:0071577	zinc ion transmembrane transport	4/2306	22/18670	0.2851	0.5084	0.3912	SLC39A14/SLC39A10/SLC39A8/SLC30A1	4
BP	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus	4/2306	22/18670	0.2851	0.5084	0.3912	BMP2/VEGFA/SESN2/SMAD9	4
BP	GO:1901685	glutathione derivative metabolic process	4/2306	22/18670	0.2851	0.5084	0.3912	GSTO1/GSTA4/ESD/MGST2	4
BP	GO:1901687	glutathione derivative biosynthetic process	4/2306	22/18670	0.2851	0.5084	0.3912	GSTO1/GSTA4/ESD/MGST2	4
BP	GO:1902806	regulation of cell cycle G1/S phase transition	28/2306	202/18670	0.2855	0.509	0.3916	BID/PSME2/CCL2/ID2/CDK6/FHL1/PSME1/PLK2/RPA2/PKD2/CCND1/KLF4/PRMT1/RDX/GJC2/CARM1/CDKN2C/BTG2/MIR137/ARID3A/CNOT8/CDK2AP2/MIR214/CTDSP2/CDKN1A/FGF10/TFDP1/MEPCE	28
BP	GO:0032945	negative regulation of mononuclear cell proliferation	11/2306	73/18670	0.2876	0.5118	0.3937	CEBPB/TNFRSF14/PDCD1LG2/IDO1/BMP4/LRRC32/MAD1L1/HAVCR2/HLA-G/SDC4/PDE5A	11
BP	GO:0044766	multi-organism transport	11/2306	73/18670	0.2876	0.5118	0.3937	IFIT1/EPS15/NUP133/VPS37D/RAB40B/VPS37C/KPNA3/UBB/KPNA2/NUP35/NMT2	11
BP	GO:0050672	negative regulation of lymphocyte proliferation	11/2306	73/18670	0.2876	0.5118	0.3937	CEBPB/TNFRSF14/PDCD1LG2/IDO1/BMP4/LRRC32/MAD1L1/HAVCR2/HLA-G/SDC4/PDE5A	11
BP	GO:0060350	endochondral bone morphogenesis	11/2306	73/18670	0.2876	0.5118	0.3937	NAB1/BMP4/COL1A1/BMPR2/HOXA11/SCARA3/CSGALNACT1/CARM1/MEF2C/COL6A3/SERPINH1	11
BP	GO:1902579	multi-organism localization	11/2306	73/18670	0.2876	0.5118	0.3937	IFIT1/EPS15/NUP133/VPS37D/RAB40B/VPS37C/KPNA3/UBB/KPNA2/NUP35/NMT2	11
BP	GO:0032091	negative regulation of protein binding	15/2306	103/18670	0.2876	0.5118	0.3937	BAG2/DAB2/ROCK1/IFIT1/PIM2/ITGA4/CSNK1E/CARM1/NKX3-1/IFIT2/ACTB/PRKCD/CRMP1/MITD1/DVL1	15
BP	GO:0035601	protein deacylation	15/2306	103/18670	0.2876	0.5118	0.3937	VEGFA/SAP30/CAMK2D/PPT1/MORF4L2/TBL1Y/SIRT1/AKAP8/PER1/MSL3/SIN3B/TBL1XR1/SMARCAD1/TADA3/SIRT6	15
BP	GO:0022404	molting cycle process	13/2306	88/18670	0.2883	0.5125	0.3943	LRIG1/LDB2/HOXC13/MSX2/ERCC2/TGFB2/WNT5A/TP63/TNF/FST/LGR4/FGF10/FERMT1	13
BP	GO:0022405	hair cycle process	13/2306	88/18670	0.2883	0.5125	0.3943	LRIG1/LDB2/HOXC13/MSX2/ERCC2/TGFB2/WNT5A/TP63/TNF/FST/LGR4/FGF10/FERMT1	13
BP	GO:0061097	regulation of protein tyrosine kinase activity	13/2306	88/18670	0.2883	0.5125	0.3943	CCL5/GPRC5A/EREG/FYN/NEDD9/TGFA/ERRFI1/ADORA1/DLG4/GAS6/CBLB/DVL2/ADRA2A	13
BP	GO:0009411	response to UV	20/2306	141/18670	0.2884	0.5126	0.3944	PTGS2/IL12A/CCND1/CDC25A/SCARA3/MAPK13/EIF2AK4/MC1R/ERCC2/TP53INP1/DDB2/BCL3/SIRT1/C9orf116/FEN1/IVL/CDKN1A/UBE4B/NEDD4/ST20	20
BP	GO:0035821	modification of morphology or physiology of other organism	23/2306	164/18670	0.2892	0.5138	0.3953	CXCL6/ZC3H12A/CCL5/TNIP1/CCL8/FBXL2/RAB9A/CALM1/RXRA/CCL3/EIF2AK4/GSDMD/HIPK2/KPNA3/IGF2R/ATG7/BCL2L1/CALM2/PTX3/ZNF639/NUCKS1/KPNA2/P2RX7	23
BP	GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	33/2306	241/18670	0.2893	0.5138	0.3953	BMP2/CITED2/DAB2/BMP4/WWTR1/GREM2/FZD1/BMPR2/THBS1/MSX2/BMPER/INHBB/SDCBP/HIPK2/TGFB2/GDF5/SIRT1/WNT5A/SULF1/GDF15/HES5/CDKN1C/FBN1/FKBP1A/FST/ABL1/CTDSPL2/UBB/ENG/FGF10/FERMT1/GDF6/ZNF451	33
BP	GO:0006213	pyrimidine nucleoside metabolic process	8/2306	51/18670	0.2909	0.5157	0.3968	TYMP/APOBEC3G/APOBEC3H/NME5/CDADC1/APOBEC3F/TK2/DCK	8
BP	GO:0007566	embryo implantation	8/2306	51/18670	0.2909	0.5157	0.3968	PTGS2/IL1B/LIF/RECK/RXRA/MMP9/ARID1A/ARHGDIB	8
BP	GO:0031050	dsRNA processing	8/2306	51/18670	0.2909	0.5157	0.3968	ZC3H12A/BMP4/ADAR/ZC3H7A/PRKRA/DDX5/PPP3CA/NCOR2	8
BP	GO:0045103	intermediate filament-based process	8/2306	51/18670	0.2909	0.5157	0.3968	KRT14/KRT16/SYNM/KRT2/CLN8/ATP8A2/PRPH/TOR1A	8
BP	GO:0045668	negative regulation of osteoblast differentiation	8/2306	51/18670	0.2909	0.5157	0.3968	ID2/CDK6/SEMA4D/TMEM64/LRP5/RANBP3L/TNF/ID3	8
BP	GO:0048641	regulation of skeletal muscle tissue development	8/2306	51/18670	0.2909	0.5157	0.3968	SIX1/ARNTL/FLOT1/SIX4/MEF2C/AKIRIN1/DDX5/MIR1-2	8
BP	GO:0070918	production of small RNA involved in gene silencing by RNA	8/2306	51/18670	0.2909	0.5157	0.3968	ZC3H12A/BMP4/ADAR/ZC3H7A/PRKRA/DDX5/PPP3CA/NCOR2	8
BP	GO:1905710	positive regulation of membrane permeability	10/2306	66/18670	0.2947	0.5223	0.4018	BID/PPP3CC/PPIF/PMAIP1/TP63/ACAA2/YWHAH/TMEM14A/TFDP1/EYA2	10
BP	GO:0030219	megakaryocyte differentiation	14/2306	96/18670	0.2949	0.5223	0.4019	KIT/MEIS1/MOV10/THBS1/PRMT1/KAT2B/MEF2C/FLI1/RBM15/RBBP5/PTPN11/PIP4K2A/WASF2/CBFB	14
BP	GO:1905037	autophagosome organization	14/2306	96/18670	0.2949	0.5223	0.4019	RAB23/GABARAPL1/TP53INP2/CHMP4B/WIPI1/RAB3GAP1/TP53INP1/RNF5/ATG7/WDR45/PACS2/PIP4K2A/FEZ2/ATP13A2	14
BP	GO:0007272	ensheathment of neurons	19/2306	134/18670	0.2955	0.5228	0.4022	NAB1/TNFRSF1B/TYMP/ARHGEF10/JAM3/CNTNAP1/MBP/EPB41L3/ERCC2/LPAR1/MALL/ABCD1/HES5/UGT8/EIF2B5/EIF2B4/SBF2/TSPAN2/CMTM8	19
BP	GO:0008366	axon ensheathment	19/2306	134/18670	0.2955	0.5228	0.4022	NAB1/TNFRSF1B/TYMP/ARHGEF10/JAM3/CNTNAP1/MBP/EPB41L3/ERCC2/LPAR1/MALL/ABCD1/HES5/UGT8/EIF2B5/EIF2B4/SBF2/TSPAN2/CMTM8	19
BP	GO:0018210	peptidyl-threonine modification	19/2306	134/18670	0.2955	0.5228	0.4022	RIPK2/PRKCA/ROCK1/CALM1/CAMK2D/DYRK2/HIPK2/CSNK1G2/CSNK1E/CDK5/WNT5A/CALM2/TRIM6/PRKCD/ROCK2/GALNT4/CSNK1G3/GALNT11/GALNT1	19
BP	GO:1902930	regulation of alcohol biosynthetic process	12/2306	81/18670	0.2956	0.5228	0.4022	BMP2/IL1B/NFKB1/ACACB/SCD/CYP27B1/TM7SF2/ACACA/VDR/TNF/GPAM/IDI1	12
BP	GO:1903533	regulation of protein targeting	12/2306	81/18670	0.2956	0.5228	0.4022	PDCD5/PAK1/FYN/ANK3/ARIH2/RHOU/CDK5/KCNB1/PARL/BAP1/GDI1/VAMP7	12
BP	GO:0043534	blood vessel endothelial cell migration	25/2306	180/18670	0.2958	0.523	0.4024	PTGS2/HSPB1/FGF2/PRKCA/VEGFA/PLK2/CD40/SLIT2/RHOJ/ETS1/KLF4/THBS1/CARD10/PIK3R3/STARD13/MEOX2/AMOTL1/ROBO1/MEF2C/SIRT1/MIR19B2/MIR137/ABL1/PPARG/MYH9	25
BP	GO:0010828	positive regulation of glucose transmembrane transport	7/2306	44/18670	0.2973	0.5253	0.4041	C3/GIP/IRS1/ADIPOR2/CLIP3/PTPN11/IGF1	7
BP	GO:0042269	regulation of natural killer cell mediated cytotoxicity	7/2306	44/18670	0.2973	0.5253	0.4041	HLA-E/IL12A/HLA-F/MICB/HAVCR2/HLA-G/NCR1	7
BP	GO:0044060	regulation of endocrine process	7/2306	44/18670	0.2973	0.5253	0.4041	IL1B/C1QTNF1/INHBB/F2R/NKX3-1/RAB11FIP1/PTPN11	7
BP	GO:0001952	regulation of cell-matrix adhesion	17/2306	119/18670	0.2983	0.5269	0.4054	NINJ1/CDK6/CSF1/CORO1C/VEGFA/ROCK1/PLAU/THBS1/DUSP3/PHLDB2/COL16A1/SDC4/SERPINE1/ABL1/ROCK2/EPHA1/FERMT1	17
BP	GO:0034332	adherens junction organization	20/2306	142/18670	0.2996	0.529	0.407	CORO1C/VEGFA/ROCK1/VCL/IQSEC1/THBS1/TRIP6/RDX/ITGA2/DUSP3/PHLDB2/ARF6/FERMT2/NUMBL/COL16A1/SDC4/MAPRE2/ABL1/ROCK2/CDH4	20
BP	GO:0001523	retinoid metabolic process	15/2306	104/18670	0.3007	0.5307	0.4083	AKR1B1/ALDH1A3/CYP27C1/GPC4/RDH10/RDH8/HSPG2/DHRS3/ADH5/SDC2/CYP1A2/SDC4/RDH13/ADH1C/CYP2S1	15
BP	GO:0098732	macromolecule deacylation	15/2306	104/18670	0.3007	0.5307	0.4083	VEGFA/SAP30/CAMK2D/PPT1/MORF4L2/TBL1Y/SIRT1/AKAP8/PER1/MSL3/SIN3B/TBL1XR1/SMARCAD1/TADA3/SIRT6	15
BP	GO:0032732	positive regulation of interleukin-1 production	9/2306	59/18670	0.3021	0.533	0.4101	RIPK2/HSPB1/PANX1/PANX2/CCL3/GSDMD/WNT5A/HAVCR2/P2RX7	9
BP	GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	13/2306	89/18670	0.3025	0.5334	0.4104	GPR37L1/S1PR3/NPR3/EDN1/AKAP12/ADCY7/RGS2/LPAR1/ADCY9/ADCY3/ADORA1/GRM2/ADRA2A	13
BP	GO:0010469	regulation of signaling receptor activity	24/2306	173/18670	0.3028	0.5334	0.4104	CCL2/PPARGC1A/GPRC5A/DAPK1/EREG/GREM2/PLAU/PDE4D/ZNF653/TGFA/PHLDA2/ERRFI1/GRIA3/LDOC1/CNRIP1/MEF2C/CDK5/ADORA1/DLG4/PRKCD/SERPINE1/CNIH2/CBLB/ADRA2A	24
BP	GO:0045727	positive regulation of translation	18/2306	127/18670	0.3029	0.5334	0.4104	CCL5/IL6/PPP1R15A/RXRA/THBS1/EIF2AK4/DNAJC3/ITGA2/MPV17L2/BCL3/PABPC1/DHX29/EIF3E/TNF/EIF2B5/FASTKD3/FXR2/YTHDF1	18
BP	GO:0032418	lysosome localization	11/2306	74/18670	0.3033	0.5334	0.4104	KIT/PIK3CD/IL4R/SNX4/RAB3A/SYTL4/STXBP1/TMEM106B/VAMP7/NPPA/MYH9	11
BP	GO:1900006	positive regulation of dendrite development	11/2306	74/18670	0.3033	0.5334	0.4104	DBN1/CAPRIN1/EEF2K/LPAR1/ITPKA/BHLHB9/ARF1/TMEM106B/VAMP7/ACTR2/ANKRD27	11
BP	GO:1900182	positive regulation of protein localization to nucleus	11/2306	74/18670	0.3033	0.5334	0.4104	ZC3H12A/PTGS2/LIF/FYN/PIK3R2/UBR5/CARD10/PARP9/SESN2/PRKCD/CHP2	11
BP	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion	6/2306	37/18670	0.3037	0.5334	0.4104	RPA2/ERCC2/DDB2/GTF2H5/UBB/RFC2	6
BP	GO:0030201	heparan sulfate proteoglycan metabolic process	6/2306	37/18670	0.3037	0.5334	0.4104	SULF2/TCF7L2/CSGALNACT1/SULF1/EXT1/HS2ST1	6
BP	GO:0031076	embryonic camera-type eye development	6/2306	37/18670	0.3037	0.5334	0.4104	ALDH1A3/RDH10/HIPK2/WNT5A/ARID1A/FGF10	6
BP	GO:0032941	secretion by tissue	6/2306	37/18670	0.3037	0.5334	0.4104	KCNN4/NPR3/CYBA/ADA/ADORA1/FGF10	6
BP	GO:0042307	positive regulation of protein import into nucleus	6/2306	37/18670	0.3037	0.5334	0.4104	ZC3H12A/PTGS2/PIK3R2/UBR5/PRKCD/CHP2	6
BP	GO:0048846	axon extension involved in axon guidance	6/2306	37/18670	0.3037	0.5334	0.4104	VEGFA/SLIT2/BMPR2/SEMA4D/WNT5A/SEMA4F	6
BP	GO:0060236	regulation of mitotic spindle organization	6/2306	37/18670	0.3037	0.5334	0.4104	CHMP1B/CHMP4B/CLTC/GPSM2/DCTN1/CHMP5	6
BP	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	6/2306	37/18670	0.3037	0.5334	0.4104	PTGS2/FGF2/VEGFA/PLK2/RHOJ/ABL1	6
BP	GO:1902284	neuron projection extension involved in neuron projection guidance	6/2306	37/18670	0.3037	0.5334	0.4104	VEGFA/SLIT2/BMPR2/SEMA4D/WNT5A/SEMA4F	6
BP	GO:0007498	mesoderm development	19/2306	135/18670	0.3071	0.5393	0.4149	CITED2/VEGFA/BMP4/IRX3/NUP133/BMPR2/KLF4/HOXA11/ITGA2/YAP1/WNT5A/TP63/PUS7/MIR1-2/EXT1/OSR1/EYA2/SSBP3/TBX3	19
BP	GO:0048193	Golgi vesicle transport	49/2306	368/18670	0.3078	0.5404	0.4157	CYTH3/NKD2/COG2/BET1/SYS1/EPS15/SORT1/NRBP2/STX6/ANK3/WIPI1/RAB33A/TGFA/GCC2/DCTN1/SEC22C/BBS2/OPTN/CAPZA2/MYO18A/KIF4B/ARF1/PREPL/OSBPL5/ARF3/BGLAP/DYNLL1/ACTR10/HYOU1/CCDC93/KLHL20/MPPE1/TMED9/GAS6/TRAPPC4/TMED10/VAMP7/TAPBP/STEAP2/ERGIC1/CNIH2/TRAPPC9/DCTN3/SERPINA1/RAB31/BICD2/COG5/RER1/VAMP5	49
BP	GO:0010596	negative regulation of endothelial cell migration	14/2306	97/18670	0.3086	0.5415	0.4166	FGF2/SLIT2/NR2F2/KLF4/THBS1/CARD10/STARD13/MEOX2/MEF2C/MIR19B2/MIR137/PTPRM/SP100/PPARG	14
BP	GO:0014020	primary neural tube formation	14/2306	97/18670	0.3086	0.5415	0.4166	BMP4/FZD1/SHROOM3/FZD2/TGFB2/WNT5A/PTK7/ARID1A/SDC4/ABL1/BCL10/RALA/DVL1/DVL2	14
BP	GO:0000038	very long-chain fatty acid metabolic process	5/2306	30/18670	0.3096	0.5415	0.4166	ELOVL5/ELOVL7/ELOVL2/ABCD1/ELOVL3	5
BP	GO:0003209	cardiac atrium morphogenesis	5/2306	30/18670	0.3096	0.5415	0.4166	BMPR2/TGFB2/WNT5A/MYH6/ENG	5
BP	GO:0006362	transcription elongation from RNA polymerase I promoter	5/2306	30/18670	0.3096	0.5415	0.4166	ERCC2/GTF2H5/MNAT1/POLR1C/CDK7	5
BP	GO:0007274	neuromuscular synaptic transmission	5/2306	30/18670	0.3096	0.5415	0.4166	RAB3A/P2RX3/CHRNB1/STXBP1/ADARB1	5
BP	GO:0021772	olfactory bulb development	5/2306	30/18670	0.3096	0.5415	0.4166	ID2/SLIT2/ROBO1/WNT5A/EXT1	5
BP	GO:0038111	interleukin-7-mediated signaling pathway	5/2306	30/18670	0.3096	0.5415	0.4166	IL7R/SOCS1/IRS1/SOCS2/STAT3	5
BP	GO:0045939	negative regulation of steroid metabolic process	5/2306	30/18670	0.3096	0.5415	0.4166	BMP2/NFKB1/INSIG2/CYP27B1/SNAI2	5
BP	GO:0051491	positive regulation of filopodium assembly	5/2306	30/18670	0.3096	0.5415	0.4166	FSCN1/FNBP1L/DPYSL3/RALA/CDC42	5
BP	GO:0090314	positive regulation of protein targeting to membrane	5/2306	30/18670	0.3096	0.5415	0.4166	PAK1/FYN/ANK3/CDK5/KCNB1	5
BP	GO:0097421	liver regeneration	5/2306	30/18670	0.3096	0.5415	0.4166	CLDN1/CEBPB/CCND1/SULF2/RGN	5
BP	GO:1905606	regulation of presynapse assembly	5/2306	30/18670	0.3096	0.5415	0.4166	FZD1/GPC4/VPS35/ARF6/LRFN4	5
BP	GO:0030514	negative regulation of BMP signaling pathway	8/2306	52/18670	0.3099	0.5416	0.4167	GREM2/FZD1/BMPER/HIPK2/WNT5A/FBN1/ABL1/CTDSPL2	8
BP	GO:0048168	regulation of neuronal synaptic plasticity	8/2306	52/18670	0.3099	0.5416	0.4167	KIT/DBN1/RAB3GAP1/RAB3A/SYT4/DLG4/NPTN/PPFIA3	8
BP	GO:2000677	regulation of transcription regulatory region DNA binding	8/2306	52/18670	0.3099	0.5416	0.4167	LIF/KLF4/MSX2/TRIM6/GATA3/IGF1/SRI/ZNF675	8
BP	GO:0090068	positive regulation of cell cycle process	40/2306	298/18670	0.3105	0.5421	0.4171	IL1B/ID2/IL1A/EREG/PLK2/PDGFRB/PKD2/CCND1/CDC25A/SMARCD3/MSX2/EDN1/PRMT1/RDX/TGFA/GPSM2/CDC14B/GATA6/LRP5/CARM1/NSMCE2/WNT5A/BTG2/ARID3A/CNOT8/PKP4/FEN1/ROCK2/MIR214/CDKN1A/FGF10/PKN2/TFDP1/CDC42/SH2B1/MEPCE/IGF1/MYBBP1A/FOXO4/NPM2	40
BP	GO:0016925	protein sumoylation	12/2306	82/18670	0.3106	0.5421	0.4171	IFIH1/NUP133/GNL3/NSMCE2/ZMIZ2/TOPORS/SUMO3/KIAA1586/RNF212/NUP35/ZNF451/PIAS3	12
BP	GO:0030279	negative regulation of ossification	12/2306	82/18670	0.3106	0.5421	0.4171	ID2/CDK6/CCL3/ENPP1/SEMA4D/TMEM64/LRP5/MEF2C/SRGN/RANBP3L/TNF/ID3	12
BP	GO:0034644	cellular response to UV	12/2306	82/18670	0.3106	0.5421	0.4171	PTGS2/CDC25A/MAPK13/EIF2AK4/MC1R/TP53INP1/DDB2/SIRT1/C9orf116/CDKN1A/NEDD4/ST20	12
BP	GO:0090049	regulation of cell migration involved in sprouting angiogenesis	12/2306	82/18670	0.3106	0.5421	0.4171	PTGS2/FGF2/VEGFA/PLK2/RHOJ/KLF4/THBS1/CARD10/STARD13/MEOX2/MIR19B2/ABL1	12
BP	GO:0072331	signal transduction by p53 class mediator	36/2306	267/18670	0.312	0.5445	0.4189	BDKRB2/PLK2/RPA2/CD44/DYRK2/PRMT1/E2F2/PMAIP1/HIPK2/TP53INP1/SNAI2/NUAK1/CARM1/CHD4/BCL3/CDK5/SIRT1/TP63/BTG2/SESN2/TAF13/DDX5/ARID3A/PPM1D/TOPORS/CNOT8/SP100/PRKAB2/UBB/CDKN1A/TFDP1/RFC2/BOP1/MYBBP1A/HINT1/RMI1	36
BP	GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	48/2306	361/18670	0.3137	0.5454	0.4196	NFKBIZ/ZC3H12A/ICAM1/TNFAIP3/IL6/CD70/IL1B/RELB/RIPK2/IL33/NFKB2/IL7R/RSAD2/C3/TNFRSF1B/IRF7/TNFSF13B/HLA-E/IL12A/IL18R1/IL4R/POU2F2/HLA-F/CD40/FADD/HLA-A/ADA/BTN3A3/EXOSC6/EBI3/CLCF1/STAT6/BCL3/MEF2C/TRAF2/MICB/HAVCR2/TNF/GATA3/PRKCD/HLA-G/HLA-DQB1/BCL10/STAT3/P2RX7/HLA-B/SASH3/HLA-H	48
BP	GO:0000715	nucleotide-excision repair, DNA damage recognition	4/2306	23/18670	0.3144	0.5454	0.4196	RAD23B/DDB2/COPS4/UBB	4
BP	GO:0002347	response to tumor cell	4/2306	23/18670	0.3144	0.5454	0.4196	IL12A/HNMT/HAVCR2/IGFBPL1	4
BP	GO:0019400	alditol metabolic process	4/2306	23/18670	0.3144	0.5454	0.4196	AKR1B1/GK/MYOF/COQ3	4
BP	GO:0032331	negative regulation of chondrocyte differentiation	4/2306	23/18670	0.3144	0.5454	0.4196	BMP4/PTHLH/SNAI2/GDF5	4
BP	GO:0032717	negative regulation of interleukin-8 production	4/2306	23/18670	0.3144	0.5454	0.4196	KLF4/BCL3/ANXA4/MAPKBP1	4
BP	GO:0032959	inositol trisphosphate biosynthetic process	4/2306	23/18670	0.3144	0.5454	0.4196	PLCD3/PLCE1/PLCD1/PLCB4	4
BP	GO:0042401	cellular biogenic amine biosynthetic process	4/2306	23/18670	0.3144	0.5454	0.4196	SAT1/SMOX/PRG3/MOXD1	4
BP	GO:0043576	regulation of respiratory gaseous exchange	4/2306	23/18670	0.3144	0.5454	0.4196	GLS/FTO/ADORA1/TSHZ3	4
BP	GO:0051570	regulation of histone H3-K9 methylation	4/2306	23/18670	0.3144	0.5454	0.4196	JARID2/MYB/LMNA/SIRT1	4
BP	GO:0060055	angiogenesis involved in wound healing	4/2306	23/18670	0.3144	0.5454	0.4196	TNFAIP3/ETS1/ADIPOR2/SERPINE1	4
BP	GO:0060294	cilium movement involved in cell motility	4/2306	23/18670	0.3144	0.5454	0.4196	TTLL1/WDR63/BBS2/RSPH9	4
BP	GO:0060445	branching involved in salivary gland morphogenesis	4/2306	23/18670	0.3144	0.5454	0.4196	SNAI2/TNF/PLXND1/FGF10	4
BP	GO:0090140	regulation of mitochondrial fission	4/2306	23/18670	0.3144	0.5454	0.4196	PPARGC1A/STAT2/TMEM135/VPS35	4
BP	GO:0097150	neuronal stem cell population maintenance	4/2306	23/18670	0.3144	0.5454	0.4196	FOXO1/HES5/HOOK3/MMP24	4
BP	GO:0051291	protein heterooligomerization	18/2306	128/18670	0.315	0.5454	0.4196	BIRC3/CLDN1/SQSTM1/BIRC2/C1QTNF1/MAT2A/COL1A1/PKD2/GCH1/CBR4/PDSS2/CPSF6/TRAF2/SYT1/COL1A2/BCL10/HBB/FARSB	18
BP	GO:0002295	T-helper cell lineage commitment	3/2306	16/18670	0.316	0.5454	0.4196	IL6/STAT6/STAT3	3
BP	GO:0003222	ventricular trabecula myocardium morphogenesis	3/2306	16/18670	0.316	0.5454	0.4196	TGFB2/ENG/UBE4B	3
BP	GO:0010225	response to UV-C	3/2306	16/18670	0.316	0.5454	0.4196	BCL3/C9orf116/ST20	3
BP	GO:0010566	regulation of ketone biosynthetic process	3/2306	16/18670	0.316	0.5454	0.4196	BMP2/PPARGC1A/COQ3	3
BP	GO:0010875	positive regulation of cholesterol efflux	3/2306	16/18670	0.316	0.5454	0.4196	NFKBIA/ABCA1/SIRT1	3
BP	GO:0010885	regulation of cholesterol storage	3/2306	16/18670	0.316	0.5454	0.4196	ABCA1/EHD1/PPARG	3
BP	GO:0014744	positive regulation of muscle adaptation	3/2306	16/18670	0.316	0.5454	0.4196	PPP3CA/MIR214/MIR199A2	3
BP	GO:0015074	DNA integration	3/2306	16/18670	0.316	0.5454	0.4196	ZNF91/SETMAR/RLF	3
BP	GO:0019377	glycolipid catabolic process	3/2306	16/18670	0.316	0.5454	0.4196	NAGA/GLA/PRKCD	3
BP	GO:0021542	dentate gyrus development	3/2306	16/18670	0.316	0.5454	0.4196	CDK6/BTG2/TMEM108	3
BP	GO:0030575	nuclear body organization	3/2306	16/18670	0.316	0.5454	0.4196	ETS1/HIPK2/SERBP1	3
BP	GO:0032305	positive regulation of icosanoid secretion	3/2306	16/18670	0.316	0.5454	0.4196	IL1B/EDN1/P2RX7	3
BP	GO:0036124	histone H3-K9 trimethylation	3/2306	16/18670	0.316	0.5454	0.4196	LMNA/SIRT1/ARID4A	3
BP	GO:0042448	progesterone metabolic process	3/2306	16/18670	0.316	0.5454	0.4196	PPARGC1A/AFP/SRD5A1	3
BP	GO:0050655	dermatan sulfate proteoglycan metabolic process	3/2306	16/18670	0.316	0.5454	0.4196	VCAN/CSGALNACT1/CSGALNACT2	3
BP	GO:0050774	negative regulation of dendrite morphogenesis	3/2306	16/18670	0.316	0.5454	0.4196	YWHAH/PPP3CA/NGEF	3
BP	GO:0070593	dendrite self-avoidance	3/2306	16/18670	0.316	0.5454	0.4196	NEXN/NPTN/PALLD	3
BP	GO:0071545	inositol phosphate catabolic process	3/2306	16/18670	0.316	0.5454	0.4196	IMPA2/INPP5B/INPP1	3
BP	GO:0072224	metanephric glomerulus development	3/2306	16/18670	0.316	0.5454	0.4196	PDGFRB/LGR4/OSR1	3
BP	GO:0086103	G protein-coupled receptor signaling pathway involved in heart process	3/2306	16/18670	0.316	0.5454	0.4196	PDE4D/RGS2/MIR1-2	3
BP	GO:0097091	synaptic vesicle clustering	3/2306	16/18670	0.316	0.5454	0.4196	RAB3A/BRSK2/PCDH17	3
BP	GO:1902992	negative regulation of amyloid precursor protein catabolic process	3/2306	16/18670	0.316	0.5454	0.4196	ROCK1/IGF1/PICALM	3
BP	GO:2000651	positive regulation of sodium ion transmembrane transporter activity	3/2306	16/18670	0.316	0.5454	0.4196	CNKSR3/ANK3/ACTN4	3
BP	GO:0032309	icosanoid secretion	7/2306	45/18670	0.318	0.548	0.4216	IL1B/BDKRB2/PLA2G4A/EDN1/PLA2G12A/NMUR2/P2RX7	7
BP	GO:0035987	endodermal cell differentiation	7/2306	45/18670	0.318	0.548	0.4216	LAMB1/ITGB5/ITGA4/COL5A2/GATA6/MMP9/COL5A1	7
BP	GO:0044275	cellular carbohydrate catabolic process	7/2306	45/18670	0.318	0.548	0.4216	GK/PYGL/CALM1/PGM2L1/PHKB/ENOSF1/PHKA2	7
BP	GO:0048483	autonomic nervous system development	7/2306	45/18670	0.318	0.548	0.4216	VCAM1/SIX1/NAV2/TP63/HES3/GATA3/ADARB1	7
BP	GO:0051932	synaptic transmission, GABAergic	7/2306	45/18670	0.318	0.548	0.4216	ADORA2A/OXTR/NISCH/ADORA1/CNR2/STXBP1/GABRA3	7
BP	GO:0007292	female gamete generation	19/2306	136/18670	0.3188	0.5492	0.4226	PTGS2/TNFAIP6/EREG/AFP/IL4R/DDX20/FMN2/INHBB/RGS2/SIRT1/NCAPH/PTX3/ZNF830/NPR2/UBB/PDE5A/IGF1/USP9X/NPM2	19
BP	GO:0043244	regulation of protein complex disassembly	16/2306	113/18670	0.3189	0.5492	0.4226	MID1/LIMA1/IRAK3/RDX/DSTN/PLEKHH2/MAP1A/CAPZA2/EPS8/GSN/TNF/PDXP/TMOD2/TAOK1/MID1IP1/CAMSAP1	16
BP	GO:0006695	cholesterol biosynthetic process	11/2306	75/18670	0.3192	0.5496	0.4228	INSIG2/ACACB/SCD/TM7SF2/ACAT2/ACACA/NPC1L1/ACAA2/HSD17B7/GPAM/IDI1	11
BP	GO:0045576	mast cell activation	9/2306	60/18670	0.32	0.5505	0.4235	KIT/PIK3CD/PLSCR1/IL4R/SNX4/CNR2/STXBP1/VAMP7/NPPA	9
BP	GO:0046794	transport of virus	9/2306	60/18670	0.32	0.5505	0.4235	EPS15/NUP133/VPS37D/VPS37C/KPNA3/UBB/KPNA2/NUP35/NMT2	9
BP	GO:1902110	positive regulation of mitochondrial membrane permeability involved in apoptotic process	9/2306	60/18670	0.32	0.5505	0.4235	BID/PPP3CC/PMAIP1/TP63/ACAA2/YWHAH/TMEM14A/TFDP1/EYA2	9
BP	GO:0006626	protein targeting to mitochondrion	14/2306	98/18670	0.3226	0.5548	0.4269	BID/PDCD5/DNAJC19/MIPEP/ARIH2/TOMM34/DNAJC15/RHOU/PARL/BAP1/GRPEL1/GRPEL2/CHCHD4/TIMM17B	14
BP	GO:0015893	drug transport	29/2306	214/18670	0.3253	0.5594	0.4304	SLC25A24/CLDN1/SLC7A2/ADORA2A/NFKBIE/ATP8B1/SLC22A2/SLC7A11/SLC22A1/ARL6IP5/EDN1/SLC19A3/RGS2/ABCC1/CYGB/RGS4/ABCC2/SYT4/ABAT/CLN8/FZD4/RALBP1/SYT1/NGB/HBB/SLC22A3/TOR1A/PTPN11/SLC19A1	29
BP	GO:0050770	regulation of axonogenesis	25/2306	183/18670	0.3261	0.5601	0.4309	ZSWIM4/NTN1/ZFYVE27/SIPA1L1/DBN1/VEGFA/PAK1/SLIT2/BMPR2/RUFY3/SEMA4D/CHN1/IFRD1/ROBO1/CDK5/WNT5A/BRSK2/PLXND1/GDI1/RTN4/ABL1/YTHDF1/SEMA4F/CDH4/MYCBP2	25
BP	GO:0007340	acrosome reaction	6/2306	38/18670	0.3265	0.5601	0.4309	AKAP3/ADCY3/TNP2/RAB3A/STXBP1/SPINK1	6
BP	GO:0016572	histone phosphorylation	6/2306	38/18670	0.3265	0.5601	0.4309	IL1B/PRKCA/RPS6KA4/CDK5/AKAP8/PRKCD	6
BP	GO:0046636	negative regulation of alpha-beta T cell activation	6/2306	38/18670	0.3265	0.5601	0.4309	ZC3H12A/ADORA2A/TNFRSF14/IL4R/SOCS1/CBFB	6
BP	GO:0050892	intestinal absorption	6/2306	38/18670	0.3265	0.5601	0.4309	ACO1/LIMA1/UGCG/NPC1L1/VDR/ADRA2A	6
BP	GO:0071867	response to monoamine	6/2306	38/18670	0.3265	0.5601	0.4309	PPARGC1A/PDE4D/SRD5A1/ABL1/PDE4B/GNG2	6
BP	GO:0071869	response to catecholamine	6/2306	38/18670	0.3265	0.5601	0.4309	PPARGC1A/PDE4D/SRD5A1/ABL1/PDE4B/GNG2	6
BP	GO:1905898	positive regulation of response to endoplasmic reticulum stress	6/2306	38/18670	0.3265	0.5601	0.4309	ERN1/PPP1R15A/HERPUD1/PMAIP1/SIRT1/TMEM33	6
BP	GO:0009799	specification of symmetry	18/2306	129/18670	0.3271	0.5611	0.4317	RTTN/AHI1/CITED2/BMP4/GREM2/PKD2/DYNC2LI1/DAAM2/SETDB2/MEF2C/OFD1/WNT5A/C9orf116/ENG/FGF10/MIB1/GALNT11/TBX3	18
BP	GO:0002286	T cell activation involved in immune response	15/2306	106/18670	0.3275	0.5616	0.4321	NFKBIZ/ZC3H12A/ICAM1/IL6/RELB/RIPK2/IL18R1/MYB/IL4R/EIF2AK4/STAT6/BCL3/HAVCR2/GATA3/STAT3	15
BP	GO:0010812	negative regulation of cell-substrate adhesion	10/2306	68/18670	0.3283	0.5623	0.4326	CORO1C/COL1A1/GBP1/THBS1/PHLDB2/TACSTD2/ACTN4/FZD4/SERPINE1/FZD7	10
BP	GO:0016239	positive regulation of macroautophagy	10/2306	68/18670	0.3283	0.5623	0.4326	RIPK2/SESN1/PIM2/RAB3GAP1/SESN3/SIRT1/OPTN/SESN2/PAFAH1B2/PIP4K2A	10
BP	GO:0031343	positive regulation of cell killing	10/2306	68/18670	0.3283	0.5623	0.4326	HLA-E/IL12A/HLA-F/FADD/HLA-A/MICB/HLA-G/P2RX7/HLA-B/HLA-H	10
BP	GO:0050918	positive chemotaxis	10/2306	68/18670	0.3283	0.5623	0.4326	CCL5/CXCL10/FGF2/VEGFA/BMP4/CCL3/ITGA2/WNT5A/PGF/FGF10	10
BP	GO:0032715	negative regulation of interleukin-6 production	8/2306	53/18670	0.3291	0.5636	0.4336	ZC3H12A/TNFAIP3/KLF2/IRAK3/SIRPA/HAVCR2/TNF/GAS6	8
BP	GO:0090150	establishment of protein localization to membrane	44/2306	332/18670	0.3313	0.5672	0.4364	BID/PPP3CC/TRAM2/PDCD5/PAK1/SYS1/FYN/CHMP4B/STX3/ANK3/RPS3A/MICALL1/RAB3GAP1/VPS37D/PMAIP1/SDCBP/VPS37C/RPL7/RPL22/BBS2/RTP4/CDK5/OPTN/ADORA1/KCNB1/RPL37A/SNAP47/VPS35/TP63/PREPL/YWHAH/SSR2/SSR1/GDI1/RPL15/VAMP7/ZDHHC18/PEX26/TFDP1/RILPL1/RAB31/GRIPAP1/VAMP5/RPS18	44
BP	GO:0051899	membrane depolarization	13/2306	91/18670	0.3316	0.5675	0.4366	ADORA2A/FHL1/GPD1L/CAMK2D/ANK3/EDN1/ABCD1/HCN4/CACNA1B/YWHAH/MIR1-2/ABL1/P2RX7	13
BP	GO:0030073	insulin secretion	28/2306	207/18670	0.3329	0.5695	0.4382	CCL5/IL1B/ENSA/PRKCA/SLC2A1/GIP/IRS1/GLUD1/HADH/TCF7L2/INHBB/ARNTL/CPT1A/RAB11FIP2/LRP5/ITPR2/KCNB1/ABAT/TNF/CAMK2G/SYTL4/DYNLL1/BRSK2/PPP3CA/PTPN11/ARL2BP/SRI/ADRA2A	28
BP	GO:0002082	regulation of oxidative phosphorylation	5/2306	31/18670	0.3352	0.5706	0.439	PPIF/PDE12/DNAJC15/ABCD1/SLC25A33	5
BP	GO:0006363	termination of RNA polymerase I transcription	5/2306	31/18670	0.3352	0.5706	0.439	ERCC2/GTF2H5/MNAT1/POLR1C/CDK7	5
BP	GO:0006658	phosphatidylserine metabolic process	5/2306	31/18670	0.3352	0.5706	0.439	OSBPL10/PLSCR1/PLA2G4A/PLA2G12A/OSBPL5	5
BP	GO:0010165	response to X-ray	5/2306	31/18670	0.3352	0.5706	0.439	CCND1/XRCC4/GATA3/NUCKS1/CDKN1A	5
BP	GO:0021988	olfactory lobe development	5/2306	31/18670	0.3352	0.5706	0.439	ID2/SLIT2/ROBO1/WNT5A/EXT1	5
BP	GO:0033687	osteoblast proliferation	5/2306	31/18670	0.3352	0.5706	0.439	BMP2/NPR3/JUNB/OSR2/ABL1	5
BP	GO:0035767	endothelial cell chemotaxis	5/2306	31/18670	0.3352	0.5706	0.439	HSPB1/FGF2/VEGFA/RAB13/THBS1	5
BP	GO:0040018	positive regulation of multicellular organism growth	5/2306	31/18670	0.3352	0.5706	0.439	CSF1/GHR/BBS2/SH3PXD2B/ATP8A2	5
BP	GO:0043304	regulation of mast cell degranulation	5/2306	31/18670	0.3352	0.5706	0.439	IL4R/SNX4/STXBP1/VAMP7/NPPA	5
BP	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	5/2306	31/18670	0.3352	0.5706	0.439	EREG/TGFA/MMP9/ADORA1/ADRA2A	5
BP	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process	5/2306	31/18670	0.3352	0.5706	0.439	VCAN/CHST7/CYTL1/CSGALNACT1/CSGALNACT2	5
BP	GO:0099174	regulation of presynapse organization	5/2306	31/18670	0.3352	0.5706	0.439	FZD1/GPC4/VPS35/ARF6/LRFN4	5
BP	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	5/2306	31/18670	0.3352	0.5706	0.439	BID/CD44/SNAI2/SIRT1/BCL2L1	5
BP	GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II	5/2306	31/18670	0.3352	0.5706	0.439	BMP2/TGFB2/GNL3/STAT3/ATOH8	5
BP	GO:2000781	positive regulation of double-strand break repair	5/2306	31/18670	0.3352	0.5706	0.439	FMN2/PARP9/MMS19/SETMAR/ACTR2	5
BP	GO:0000422	autophagy of mitochondrion	11/2306	76/18670	0.3353	0.5706	0.439	PPARGC1A/SQSTM1/GABARAPL1/HK2/WIPI1/OPTN/ATG7/CAMKK2/WDR45/VDAC1/ATP13A2	11
BP	GO:0001937	negative regulation of endothelial cell proliferation	11/2306	76/18670	0.3353	0.5706	0.439	CCL2/STAT1/NR2F2/THBS1/MEF2C/SULF1/TNF/SPARC/PTPRM/PPARG/ATOH8	11
BP	GO:0061726	mitochondrion disassembly	11/2306	76/18670	0.3353	0.5706	0.439	PPARGC1A/SQSTM1/GABARAPL1/HK2/WIPI1/OPTN/ATG7/CAMKK2/WDR45/VDAC1/ATP13A2	11
BP	GO:1902653	secondary alcohol biosynthetic process	11/2306	76/18670	0.3353	0.5706	0.439	INSIG2/ACACB/SCD/TM7SF2/ACAT2/ACACA/NPC1L1/ACAA2/HSD17B7/GPAM/IDI1	11
BP	GO:0030838	positive regulation of actin filament polymerization	14/2306	99/18670	0.3367	0.5728	0.4407	ICAM1/ARPC1A/CDC42EP1/ACTR3/CDC42EP3/FMN2/ARPC2/ARF6/ARF1/PFN2/GSN/GMFB/ACTR2/MAGEL2	14
BP	GO:0045927	positive regulation of growth	36/2306	270/18670	0.3373	0.5738	0.4415	CSF1/NTN1/BASP1/FGF2/ZFYVE27/DBN1/VEGFA/PAK1/ACACB/BMPR2/RUFY3/CYBA/PIM1/EDN1/HBEGF/GHR/SDCBP/SEMA4D/TGFB2/GATA6/BBS2/YAP1/MEF2C/MIR19B2/SYT4/SH3PXD2B/ATP8A2/GDI1/SYT1/ZNF639/SLC25A33/CDC42/MIR199A2/IGF1/CDH4/SASH3	36
BP	GO:0007405	neuroblast proliferation	9/2306	61/18670	0.338	0.5745	0.442	VEGFA/EML1/SMARCD3/SOX5/DAGLA/MIR137/NUMBL/DAGLB/AKNA	9
BP	GO:0090303	positive regulation of wound healing	9/2306	61/18670	0.338	0.5745	0.442	PDPN/THBS1/HBEGF/F2R/MYLK/SERPINE1/MIR199A2/SERPINF2/ADRA2A	9
BP	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	9/2306	61/18670	0.338	0.5745	0.442	BID/PLEKHF1/BCLAF1/PMAIP1/SIRT1/NKX3-1/BCL2L1/PRKRA/UBB	9
BP	GO:0002715	regulation of natural killer cell mediated immunity	7/2306	46/18670	0.3389	0.5749	0.4423	HLA-E/IL12A/HLA-F/MICB/HAVCR2/HLA-G/NCR1	7
BP	GO:0006984	ER-nucleus signaling pathway	7/2306	46/18670	0.3389	0.5749	0.4423	CCL2/INSIG2/PPP1R15A/HERPUD1/ATP2A2/ASNS/TMEM33	7
BP	GO:0035088	establishment or maintenance of apical/basal cell polarity	7/2306	46/18670	0.3389	0.5749	0.4423	FSCN1/LIN7A/WNT5A/PTK7/CDC42/LIN7C/PDCD6IP	7
BP	GO:0048512	circadian behavior	7/2306	46/18670	0.3389	0.5749	0.4423	CSF2/ID2/ADORA2A/ADA/SRD5A1/ZFHX3/ADORA1	7
BP	GO:0061245	establishment or maintenance of bipolar cell polarity	7/2306	46/18670	0.3389	0.5749	0.4423	FSCN1/LIN7A/WNT5A/PTK7/CDC42/LIN7C/PDCD6IP	7
BP	GO:1904738	vascular associated smooth muscle cell migration	7/2306	46/18670	0.3389	0.5749	0.4423	PAK1/SSH1/MEF2C/MIR137/DOCK4/MIR214/MIR218-1	7
BP	GO:1904752	regulation of vascular associated smooth muscle cell migration	7/2306	46/18670	0.3389	0.5749	0.4423	PAK1/SSH1/MEF2C/MIR137/DOCK4/MIR214/MIR218-1	7
BP	GO:0048705	skeletal system morphogenesis	32/2306	239/18670	0.3401	0.5768	0.4438	NAB1/RAB23/ARID5B/SIX1/INSIG2/BMP4/IRX5/COL1A1/RDH10/BMPR2/HOXA11/DHRS3/MSX2/SCARA3/CSGALNACT1/THRA/HOXD9/HAS2/LRP5/CARM1/SIX4/MEF2C/COL6A3/PRKRA/HOXD3/SH3PXD2B/OSR2/SERPINH1/HOXB7/ANKRD11/OSR1/P2RX7	32
BP	GO:0030307	positive regulation of cell growth	23/2306	169/18670	0.3422	0.5775	0.4443	NTN1/ZFYVE27/DBN1/VEGFA/PAK1/BMPR2/RUFY3/CYBA/EDN1/HBEGF/SDCBP/SEMA4D/TGFB2/MIR19B2/SYT4/GDI1/SYT1/ZNF639/SLC25A33/CDC42/MIR199A2/IGF1/CDH4	23
BP	GO:0002861	regulation of inflammatory response to antigenic stimulus	4/2306	24/18670	0.3439	0.5775	0.4443	C3/HLA-E/PSMA1/TNF	4
BP	GO:0007097	nuclear migration	4/2306	24/18670	0.3439	0.5775	0.4443	NTN1/FHOD1/HOOK3/MYH10	4
BP	GO:0009309	amine biosynthetic process	4/2306	24/18670	0.3439	0.5775	0.4443	SAT1/SMOX/PRG3/MOXD1	4
BP	GO:0010288	response to lead ion	4/2306	24/18670	0.3439	0.5775	0.4443	PTGS2/CLDN1/BACE1/SPARC	4
BP	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	4/2306	24/18670	0.3439	0.5775	0.4443	GAS6/PYDC2/ZNF675/PELI3	4
BP	GO:0014850	response to muscle activity	4/2306	24/18670	0.3439	0.5775	0.4443	PPARGC1A/SRD5A1/ITGA2/FNDC5	4
BP	GO:0031579	membrane raft organization	4/2306	24/18670	0.3439	0.5775	0.4443	MYADM/PPT1/FLOT1/GSN	4
BP	GO:0033081	regulation of T cell differentiation in thymus	4/2306	24/18670	0.3439	0.5775	0.4443	IL7R/BMP4/ADA/ADAM8	4
BP	GO:0034505	tooth mineralization	4/2306	24/18670	0.3439	0.5775	0.4443	FOXO1/COL1A1/MSX2/STIM1	4
BP	GO:0036315	cellular response to sterol	4/2306	24/18670	0.3439	0.5775	0.4443	ABCA1/NFE2L1/OSBPL7/GRAMD1A	4
BP	GO:0042430	indole-containing compound metabolic process	4/2306	24/18670	0.3439	0.5775	0.4443	KYNU/IDO1/SRD5A1/AADAT	4
BP	GO:0042537	benzene-containing compound metabolic process	4/2306	24/18670	0.3439	0.5775	0.4443	CYP4B1/KYNU/IDO1/AADAT	4
BP	GO:0044346	fibroblast apoptotic process	4/2306	24/18670	0.3439	0.5775	0.4443	BID/API5/TP63/GAS6	4
BP	GO:0045606	positive regulation of epidermal cell differentiation	4/2306	24/18670	0.3439	0.5775	0.4443	BMP4/CYP27B1/VDR/SULT2B1	4
BP	GO:0046174	polyol catabolic process	4/2306	24/18670	0.3439	0.5775	0.4443	GK/IMPA2/INPP5B/INPP1	4
BP	GO:0046639	negative regulation of alpha-beta T cell differentiation	4/2306	24/18670	0.3439	0.5775	0.4443	ZC3H12A/IL4R/SOCS1/CBFB	4
BP	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway	4/2306	24/18670	0.3439	0.5775	0.4443	KCNN4/SLC39A10/CYLD/ADA	4
BP	GO:0051446	positive regulation of meiotic cell cycle	4/2306	24/18670	0.3439	0.5775	0.4443	CDC25A/MSX2/WNT5A/NPM2	4
BP	GO:1905564	positive regulation of vascular endothelial cell proliferation	4/2306	24/18670	0.3439	0.5775	0.4443	FGF2/ITGA4/STAT3/SIRT6	4
BP	GO:2001026	regulation of endothelial cell chemotaxis	4/2306	24/18670	0.3439	0.5775	0.4443	HSPB1/FGF2/VEGFA/THBS1	4
BP	GO:0048469	cell maturation	24/2306	177/18670	0.3445	0.5775	0.4443	ID2/EPAS1/C3/VEGFA/EREG/KLF2/IRX5/POU2F2/MTCH1/IL15/ERCC2/AXL/HES5/CDKN1C/CEBPA/SPINK1/GATA3/NPR2/SLC26A3/PPARG/CDKN1A/ANKS1A/BSPH1/CBFB	24
BP	GO:0050771	negative regulation of axonogenesis	10/2306	69/18670	0.3454	0.5775	0.4443	NTN1/SLIT2/RUFY3/SEMA4D/IFRD1/CDK5/WNT5A/GDI1/RTN4/SEMA4F	10
BP	GO:0086003	cardiac muscle cell contraction	10/2306	69/18670	0.3454	0.5775	0.4443	GPD1L/PDE4D/CAMK2D/SGCD/ADORA1/MIR1-2/SNTA1/PDE4B/KCND3/SRI	10
BP	GO:0061337	cardiac conduction	20/2306	146/18670	0.3456	0.5775	0.4443	GJD3/CALM1/PDE4D/CAMK2D/DMPK/TRPC1/HCN4/ITPR2/KCND1/CACNA1F/CALM2/ATP2A2/MIR1-2/STIM1/NPR2/KCND3/ATP1A4/NPPA/SRI/CASQ1	20
BP	GO:0018205	peptidyl-lysine modification	52/2306	397/18670	0.3461	0.5775	0.4443	IL1B/LIF/BRPF3/IFIH1/PPARGC1A/JARID2/AUTS2/MYB/SET/SENP7/LOXL4/NUP133/LMNA/DR1/KAT2B/SMYD3/SNAI2/MORF4L2/RPS6KA4/PLOD2/SETDB2/YEATS2/GNL3/NSMCE2/NDUFAB1/SIRT1/ZMIZ2/LOXL1/TOPORS/SUMO3/TET3/RBBP5/MSL1/GATA3/IWS1/IVL/KIAA1586/SETMAR/SETD5/TAF6L/PER1/RLF/RNF212/NUP35/GTF3C4/DHPS/MSL3/ZNF451/PIAS3/TADA3/ARID4A/PHF10	52
BP	GO:1902275	regulation of chromatin organization	25/2306	185/18670	0.3467	0.5775	0.4443	IL1B/LIF/PPARGC1A/JARID2/AUTS2/VEGFA/RNF20/MYB/SET/CAMK2D/LMNA/TET1/UBR5/SNAI2/RPS6KA4/SIRT1/AKAP8/TLK1/GATA3/IWS1/SETD5/ASF1A/ZNF451/TADA3/SIRT6	25
BP	GO:0008207	C21-steroid hormone metabolic process	6/2306	39/18670	0.3495	0.5775	0.4443	BMP2/AKR1B1/PPARGC1A/AFP/SRD5A1/STARD3NL	6
BP	GO:0033683	nucleotide-excision repair, DNA incision	6/2306	39/18670	0.3495	0.5775	0.4443	RPA2/ERCC2/DDB2/GTF2H5/UBB/RFC2	6
BP	GO:0042417	dopamine metabolic process	6/2306	39/18670	0.3495	0.5775	0.4443	PNKD/GCH1/TGFB2/MOXD1/VPS35/ABAT	6
BP	GO:0042769	DNA damage response, detection of DNA damage	6/2306	39/18670	0.3495	0.5775	0.4443	DNAJA1/RPA2/MRPS35/MRPS9/UBB/RFC2	6
BP	GO:0048713	regulation of oligodendrocyte differentiation	6/2306	39/18670	0.3495	0.5775	0.4443	ID2/TNFRSF1B/DAAM2/HES5/DUSP10/PPARG	6
BP	GO:0051930	regulation of sensory perception of pain	6/2306	39/18670	0.3495	0.5775	0.4443	CCL3/EDN1/F2R/ADORA1/P2RX3/NMUR2	6
BP	GO:1902116	negative regulation of organelle assembly	6/2306	39/18670	0.3495	0.5775	0.4443	CHMP4B/TRIM37/KAT2B/TCHP/EVI5L/FEZ2	6
BP	GO:0036503	ERAD pathway	14/2306	100/18670	0.3509	0.5775	0.4443	UBE4A/TRIM25/HERPUD1/DNAJB9/NCCRP1/RNF5/RCN3/UBXN1/USP14/BRSK2/FBXO17/TOR1A/UBE4B/RNF121	14
BP	GO:0001522	pseudouridine synthesis	3/2306	17/18670	0.3518	0.5775	0.4443	PUS7L/PUS10/PUS7	3
BP	GO:0001675	acrosome assembly	3/2306	17/18670	0.3518	0.5775	0.4443	CCDC136/ZPBP2/RFX2	3
BP	GO:0006586	indolalkylamine metabolic process	3/2306	17/18670	0.3518	0.5775	0.4443	KYNU/IDO1/AADAT	3
BP	GO:0006595	polyamine metabolic process	3/2306	17/18670	0.3518	0.5775	0.4443	SAT1/SMOX/DHPS	3
BP	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	3/2306	17/18670	0.3518	0.5775	0.4443	HIPK2/SP100/CDKN1A	3
BP	GO:0010224	response to UV-B	3/2306	17/18670	0.3518	0.5775	0.4443	IL12A/IVL/CDKN1A	3
BP	GO:0010744	positive regulation of macrophage derived foam cell differentiation	3/2306	17/18670	0.3518	0.5775	0.4443	CSF2/NFKB1/CSF1	3
BP	GO:0010819	regulation of T cell chemotaxis	3/2306	17/18670	0.3518	0.5775	0.4443	CCL5/CXCL10/WNT5A	3
BP	GO:0014733	regulation of skeletal muscle adaptation	3/2306	17/18670	0.3518	0.5775	0.4443	CAMK2G/ATP2A2/PPP3CA	3
BP	GO:0017085	response to insecticide	3/2306	17/18670	0.3518	0.5775	0.4443	ZC3H12A/DAXX/MAPK13	3
BP	GO:0017121	phospholipid scrambling	3/2306	17/18670	0.3518	0.5775	0.4443	PLSCR1/PLSCR2/P2RX7	3
BP	GO:0018904	ether metabolic process	3/2306	17/18670	0.3518	0.5775	0.4443	TXN/FAR1/DHRS7B	3
BP	GO:0030011	maintenance of cell polarity	3/2306	17/18670	0.3518	0.5775	0.4443	LIN7A/LIN7C/PDCD6IP	3
BP	GO:0031000	response to caffeine	3/2306	17/18670	0.3518	0.5775	0.4443	ADORA2A/PPARGC1A/PPARG	3
BP	GO:0032740	positive regulation of interleukin-17 production	3/2306	17/18670	0.3518	0.5775	0.4443	IL6/IL15/CCL1	3
BP	GO:0036270	response to diuretic	3/2306	17/18670	0.3518	0.5775	0.4443	ADORA2A/PPARGC1A/PPARG	3
BP	GO:0042753	positive regulation of circadian rhythm	3/2306	17/18670	0.3518	0.5775	0.4443	ADORA2A/ARNTL/ARNTL2	3
BP	GO:0043373	CD4-positive, alpha-beta T cell lineage commitment	3/2306	17/18670	0.3518	0.5775	0.4443	IL6/STAT6/STAT3	3
BP	GO:0043649	dicarboxylic acid catabolic process	3/2306	17/18670	0.3518	0.5775	0.4443	GLUD1/ACOT8/ALDH1L2	3
BP	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate	3/2306	17/18670	0.3518	0.5775	0.4443	APOBEC3G/APOBEC3H/APOBEC3F	3
BP	GO:0045725	positive regulation of glycogen biosynthetic process	3/2306	17/18670	0.3518	0.5775	0.4443	IRS1/DYRK2/IGF1	3
BP	GO:0048521	negative regulation of behavior	3/2306	17/18670	0.3518	0.5775	0.4443	ADA/ARRDC3/ADORA1	3
BP	GO:0055070	copper ion homeostasis	3/2306	17/18670	0.3518	0.5775	0.4443	MT2A/ARF1/CUTC	3
BP	GO:0060644	mammary gland epithelial cell differentiation	3/2306	17/18670	0.3518	0.5775	0.4443	ID2/CEBPB/LBH	3
BP	GO:0060850	regulation of transcription involved in cell fate commitment	3/2306	17/18670	0.3518	0.5775	0.4443	CEBPB/NR2F2/PPARG	3
BP	GO:0061577	calcium ion transmembrane transport via high voltage-gated calcium channel	3/2306	17/18670	0.3518	0.5775	0.4443	CAMK2D/MIR1-2/NPPA	3
BP	GO:0070166	enamel mineralization	3/2306	17/18670	0.3518	0.5775	0.4443	FOXO1/MSX2/STIM1	3
BP	GO:0071850	mitotic cell cycle arrest	3/2306	17/18670	0.3518	0.5775	0.4443	CDC14B/NKX3-1/CDKN1A	3
BP	GO:0098856	intestinal lipid absorption	3/2306	17/18670	0.3518	0.5775	0.4443	LIMA1/UGCG/NPC1L1	3
BP	GO:0099010	modification of postsynaptic structure	3/2306	17/18670	0.3518	0.5775	0.4443	PFN2/STAU1/MYH10	3
BP	GO:1902931	negative regulation of alcohol biosynthetic process	3/2306	17/18670	0.3518	0.5775	0.4443	BMP2/NFKB1/CYP27B1	3
BP	GO:1903975	regulation of glial cell migration	3/2306	17/18670	0.3518	0.5775	0.4443	CSF1/CCL3/CRKL	3
BP	GO:1904948	midbrain dopaminergic neuron differentiation	3/2306	17/18670	0.3518	0.5775	0.4443	FZD1/CSNK1E/WNT5A	3
BP	GO:2000641	regulation of early endosome to late endosome transport	3/2306	17/18670	0.3518	0.5775	0.4443	DAB2/RDX/SNX3	3
BP	GO:2000811	negative regulation of anoikis	3/2306	17/18670	0.3518	0.5775	0.4443	SNAI2/PTRH2/TLE1	3
BP	GO:0030004	cellular monovalent inorganic cation homeostasis	15/2306	108/18670	0.3548	0.5775	0.4443	ATP6V1E2/ATP6V0B/RAB38/ATP6V0E2/MAFG/PPT1/TMEM175/SLAMF8/DMXL1/SLC26A3/ATP1A4/ROGDI/ATP6V1E1/SLC9A9/TMEM165	15
BP	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA	2/2306	10/18670	0.3554	0.5775	0.4443	DCP1A/PATL1	2
BP	GO:0000338	protein deneddylation	2/2306	10/18670	0.3554	0.5775	0.4443	COPS4/TOR1A	2
BP	GO:0001768	establishment of T cell polarity	2/2306	10/18670	0.3554	0.5775	0.4443	GSN/MYH9	2
BP	GO:0001787	natural killer cell proliferation	2/2306	10/18670	0.3554	0.5775	0.4443	HLA-E/IL15	2
BP	GO:0001840	neural plate development	2/2306	10/18670	0.3554	0.5775	0.4443	DVL1/DVL2	2
BP	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	2/2306	10/18670	0.3554	0.5775	0.4443	ICAM1/HAVCR2	2
BP	GO:0002934	desmosome organization	2/2306	10/18670	0.3554	0.5775	0.4443	PRKCA/SNAI2	2
BP	GO:0003211	cardiac ventricle formation	2/2306	10/18670	0.3554	0.5775	0.4443	SMARCD3/MEF2C	2
BP	GO:0003376	sphingosine-1-phosphate receptor signaling pathway	2/2306	10/18670	0.3554	0.5775	0.4443	S1PR3/S1PR5	2
BP	GO:0006002	fructose 6-phosphate metabolic process	2/2306	10/18670	0.3554	0.5775	0.4443	GFPT2/NFE2L1	2
BP	GO:0006307	DNA dealkylation involved in DNA repair	2/2306	10/18670	0.3554	0.5775	0.4443	FTO/ASCC3	2
BP	GO:0006547	histidine metabolic process	2/2306	10/18670	0.3554	0.5775	0.4443	MTHFD2L/HNMT	2
BP	GO:0006971	hypotonic response	2/2306	10/18670	0.3554	0.5775	0.4443	ITGA2/MYLK	2
BP	GO:0007084	mitotic nuclear envelope reassembly	2/2306	10/18670	0.3554	0.5775	0.4443	LMNA/ANKLE2	2
BP	GO:0007168	receptor guanylyl cyclase signaling pathway	2/2306	10/18670	0.3554	0.5775	0.4443	NPR2/NPPA	2
BP	GO:0010998	regulation of translational initiation by eIF2 alpha phosphorylation	2/2306	10/18670	0.3554	0.5775	0.4443	EIF2AK4/DNAJC3	2
BP	GO:0015937	coenzyme A biosynthetic process	2/2306	10/18670	0.3554	0.5775	0.4443	ACAT1/PPCS	2
BP	GO:0016102	diterpenoid biosynthetic process	2/2306	10/18670	0.3554	0.5775	0.4443	ALDH1A3/RDH10	2
BP	GO:0018065	protein-cofactor linkage	2/2306	10/18670	0.3554	0.5775	0.4443	NDUFAB1/SDHAF2	2
BP	GO:0018242	protein O-linked glycosylation via serine	2/2306	10/18670	0.3554	0.5775	0.4443	GALNT4/GALNT1	2
BP	GO:0019062	virion attachment to host cell	2/2306	10/18670	0.3554	0.5775	0.4443	ICAM1/GAS6	2
BP	GO:0030647	aminoglycoside antibiotic metabolic process	2/2306	10/18670	0.3554	0.5775	0.4443	AKR1B1/CBR4	2
BP	GO:0032070	regulation of deoxyribonuclease activity	2/2306	10/18670	0.3554	0.5775	0.4443	SIRT1/PRKCD	2
BP	GO:0033131	regulation of glucokinase activity	2/2306	10/18670	0.3554	0.5775	0.4443	COX11/DUSP12	2
BP	GO:0033182	regulation of histone ubiquitination	2/2306	10/18670	0.3554	0.5775	0.4443	RNF20/UBR5	2
BP	GO:0033483	gas homeostasis	2/2306	10/18670	0.3554	0.5775	0.4443	SOD2/EGLN1	2
BP	GO:0033690	positive regulation of osteoblast proliferation	2/2306	10/18670	0.3554	0.5775	0.4443	BMP2/ABL1	2
BP	GO:0034058	endosomal vesicle fusion	2/2306	10/18670	0.3554	0.5775	0.4443	SAMD9L/SAMD9	2
BP	GO:0034454	microtubule anchoring at centrosome	2/2306	10/18670	0.3554	0.5775	0.4443	DCTN1/HOOK3	2
BP	GO:0035845	photoreceptor cell outer segment organization	2/2306	10/18670	0.3554	0.5775	0.4443	AHI1/TOPORS	2
BP	GO:0035865	cellular response to potassium ion	2/2306	10/18670	0.3554	0.5775	0.4443	PPARGC1A/DLG4	2
BP	GO:0035999	tetrahydrofolate interconversion	2/2306	10/18670	0.3554	0.5775	0.4443	MTHFD2L/MTHFD2	2
BP	GO:0042536	negative regulation of tumor necrosis factor biosynthetic process	2/2306	10/18670	0.3554	0.5775	0.4443	ERRFI1/BCL3	2
BP	GO:0042758	long-chain fatty acid catabolic process	2/2306	10/18670	0.3554	0.5775	0.4443	AIG1/ABCD1	2
BP	GO:0043084	penile erection	2/2306	10/18670	0.3554	0.5775	0.4443	OXTR/ADA	2
BP	GO:0044557	relaxation of smooth muscle	2/2306	10/18670	0.3554	0.5775	0.4443	RGS2/ADORA1	2
BP	GO:0044803	multi-organism membrane organization	2/2306	10/18670	0.3554	0.5775	0.4443	PPIA/GAS6	2
BP	GO:0045625	regulation of T-helper 1 cell differentiation	2/2306	10/18670	0.3554	0.5775	0.4443	RIPK2/IL4R	2
BP	GO:0045657	positive regulation of monocyte differentiation	2/2306	10/18670	0.3554	0.5775	0.4443	CSF1/ACIN1	2
BP	GO:0045876	positive regulation of sister chromatid cohesion	2/2306	10/18670	0.3554	0.5775	0.4443	NSMCE2/FEN1	2
BP	GO:0045945	positive regulation of transcription by RNA polymerase III	2/2306	10/18670	0.3554	0.5775	0.4443	CEBPA/ELL	2
BP	GO:0046322	negative regulation of fatty acid oxidation	2/2306	10/18670	0.3554	0.5775	0.4443	ACACB/APPL2	2
BP	GO:0046485	ether lipid metabolic process	2/2306	10/18670	0.3554	0.5775	0.4443	FAR1/DHRS7B	2
BP	GO:0046498	S-adenosylhomocysteine metabolic process	2/2306	10/18670	0.3554	0.5775	0.4443	GAMT/GNMT	2
BP	GO:0046710	GDP metabolic process	2/2306	10/18670	0.3554	0.5775	0.4443	NUDT18/GUK1	2
BP	GO:0048021	regulation of melanin biosynthetic process	2/2306	10/18670	0.3554	0.5775	0.4443	SLC7A11/WNT5A	2
BP	GO:0048703	embryonic viscerocranium morphogenesis	2/2306	10/18670	0.3554	0.5775	0.4443	RDH10/MEF2C	2
BP	GO:0051124	synaptic growth at neuromuscular junction	2/2306	10/18670	0.3554	0.5775	0.4443	SIX1/SIX4	2
BP	GO:0051255	spindle midzone assembly	2/2306	10/18670	0.3554	0.5775	0.4443	LZTS2/KIF4B	2
BP	GO:0060033	anatomical structure regression	2/2306	10/18670	0.3554	0.5775	0.4443	NINJ1/CD248	2
BP	GO:0060068	vagina development	2/2306	10/18670	0.3554	0.5775	0.4443	AXL/WNT5A	2
BP	GO:0060346	bone trabecula formation	2/2306	10/18670	0.3554	0.5775	0.4443	COL1A1/MSX2	2
BP	GO:0060923	cardiac muscle cell fate commitment	2/2306	10/18670	0.3554	0.5775	0.4443	MIR19B2/TBX3	2
BP	GO:0061635	regulation of protein complex stability	2/2306	10/18670	0.3554	0.5775	0.4443	SQSTM1/TAPBP	2
BP	GO:0070091	glucagon secretion	2/2306	10/18670	0.3554	0.5775	0.4443	IL6/GIP	2
BP	GO:0070314	G1 to G0 transition	2/2306	10/18670	0.3554	0.5775	0.4443	CYP27B1/PHGDH	2
BP	GO:0070472	regulation of uterine smooth muscle contraction	2/2306	10/18670	0.3554	0.5775	0.4443	OXTR/ABAT	2
BP	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain	2/2306	10/18670	0.3554	0.5775	0.4443	PPIL4/GTF2H5	2
BP	GO:0071104	response to interleukin-9	2/2306	10/18670	0.3554	0.5775	0.4443	STAT1/STAT3	2
BP	GO:0071501	cellular response to sterol depletion	2/2306	10/18670	0.3554	0.5775	0.4443	INSIG2/NPC1L1	2
BP	GO:0071600	otic vesicle morphogenesis	2/2306	10/18670	0.3554	0.5775	0.4443	CEP290/FGF10	2
BP	GO:0072641	type I interferon secretion	2/2306	10/18670	0.3554	0.5775	0.4443	IFIH1/DDX58	2
BP	GO:0090336	positive regulation of brown fat cell differentiation	2/2306	10/18670	0.3554	0.5775	0.4443	PTGS2/FNDC5	2
BP	GO:0097048	dendritic cell apoptotic process	2/2306	10/18670	0.3554	0.5775	0.4443	AXL/GAS6	2
BP	GO:0106049	regulation of cellular response to osmotic stress	2/2306	10/18670	0.3554	0.5775	0.4443	PTGS2/BDKRB2	2
BP	GO:1900222	negative regulation of amyloid-beta clearance	2/2306	10/18670	0.3554	0.5775	0.4443	IFNGR1/TNF	2
BP	GO:1900426	positive regulation of defense response to bacterium	2/2306	10/18670	0.3554	0.5775	0.4443	CYBA/HAVCR2	2
BP	GO:1901033	positive regulation of response to reactive oxygen species	2/2306	10/18670	0.3554	0.5775	0.4443	RGN/TNF	2
BP	GO:1901725	regulation of histone deacetylase activity	2/2306	10/18670	0.3554	0.5775	0.4443	VEGFA/CAMK2D	2
BP	GO:1902237	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	2/2306	10/18670	0.3554	0.5775	0.4443	PMAIP1/SIRT1	2
BP	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA	2/2306	10/18670	0.3554	0.5775	0.4443	BMP4/DDX5	2
BP	GO:1903897	regulation of PERK-mediated unfolded protein response	2/2306	10/18670	0.3554	0.5775	0.4443	PPP1R15A/TMEM33	2
BP	GO:1904350	regulation of protein catabolic process in the vacuole	2/2306	10/18670	0.3554	0.5775	0.4443	VPS35/ATP13A2	2
BP	GO:1904684	negative regulation of metalloendopeptidase activity	2/2306	10/18670	0.3554	0.5775	0.4443	RECK/PICALM	2
BP	GO:1904779	regulation of protein localization to centrosome	2/2306	10/18670	0.3554	0.5775	0.4443	CEP250/MARK4	2
BP	GO:1904896	ESCRT complex disassembly	2/2306	10/18670	0.3554	0.5775	0.4443	CHMP1B/CHMP5	2
BP	GO:1904903	ESCRT III complex disassembly	2/2306	10/18670	0.3554	0.5775	0.4443	CHMP1B/CHMP5	2
BP	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus	2/2306	10/18670	0.3554	0.5775	0.4443	EEF2K/TMEM108	2
BP	GO:2000035	regulation of stem cell division	2/2306	10/18670	0.3554	0.5775	0.4443	LBH/CDK2AP2	2
BP	GO:2000271	positive regulation of fibroblast apoptotic process	2/2306	10/18670	0.3554	0.5775	0.4443	BID/TP63	2
BP	GO:2000425	regulation of apoptotic cell clearance	2/2306	10/18670	0.3554	0.5775	0.4443	CCL2/C3	2
BP	GO:2000480	negative regulation of cAMP-dependent protein kinase activity	2/2306	10/18670	0.3554	0.5775	0.4443	SIRT1/PKIG	2
BP	GO:2000628	regulation of miRNA metabolic process	2/2306	10/18670	0.3554	0.5775	0.4443	ZC3H12A/NFKB1	2
BP	GO:2000644	regulation of receptor catabolic process	2/2306	10/18670	0.3554	0.5775	0.4443	ITCH/MYLIP	2
BP	GO:2000665	regulation of interleukin-13 secretion	2/2306	10/18670	0.3554	0.5775	0.4443	IL17RB/GATA3	2
BP	GO:2000668	regulation of dendritic cell apoptotic process	2/2306	10/18670	0.3554	0.5775	0.4443	AXL/GAS6	2
BP	GO:2000833	positive regulation of steroid hormone secretion	2/2306	10/18670	0.3554	0.5775	0.4443	C1QTNF1/NKX3-1	2
BP	GO:2001135	regulation of endocytic recycling	2/2306	10/18670	0.3554	0.5775	0.4443	EHD1/ARHGAP1	2
BP	GO:0003002	regionalization	46/2306	351/18670	0.3561	0.5786	0.4452	BMP2/AHI1/CITED2/BASP1/MAFB/SIX1/C3/BMP4/GREM2/HOXC13/IRX3/NR2F2/BMPR2/HOXA11/SMARCD3/MSX2/EDN1/HOXA10/HIPK2/SPRY1/HOXD9/MEOX2/LRP5/SETDB2/ROBO1/MEF2C/WNT5A/NKX3-1/TP63/BTG2/HES5/HES3/HOXD3/GPR161/HOXA9/HOXB7/GRSF1/MNS1/FGF10/MIB1/OSR1/DVL2/BPTF/CRKL/SSBP3/TBX3	46
BP	GO:0007585	respiratory gaseous exchange	9/2306	62/18670	0.3563	0.5786	0.4452	MAFB/GLS/FTO/EDN1/HNMT/ADH5/ADORA1/RAB3A/TSHZ3	9
BP	GO:0019359	nicotinamide nucleotide biosynthetic process	20/2306	147/18670	0.3574	0.58	0.4462	NAMPT/PTGS2/PPARGC1A/SLC2A6/KYNU/IDO1/HK2/ENO2/ADPGK/NUP133/PGM2L1/NNMT/PARP9/PGAM4/NUP35/IGF1/STAT3/ALDOC/P2RX7/SIRT6	20
BP	GO:0019363	pyridine nucleotide biosynthetic process	20/2306	147/18670	0.3574	0.58	0.4462	NAMPT/PTGS2/PPARGC1A/SLC2A6/KYNU/IDO1/HK2/ENO2/ADPGK/NUP133/PGM2L1/NNMT/PARP9/PGAM4/NUP35/IGF1/STAT3/ALDOC/P2RX7/SIRT6	20
BP	GO:0061351	neural precursor cell proliferation	20/2306	147/18670	0.3574	0.58	0.4462	GPR37L1/ID2/DBN1/FOXO1/VEGFA/EML1/LIMS2/SMARCD3/DIXDC1/SOX5/GJC2/DAGLA/WNT5A/BTG2/MIR137/APPL2/HOOK3/NUMBL/DAGLB/AKNA	20
BP	GO:0016570	histone modification	59/2306	454/18670	0.3575	0.58	0.4462	IL1B/LIF/BRPF3/PPARGC1A/PRKCA/JARID2/AUTS2/VEGFA/RNF20/MYB/SET/SAP30/CAMK2D/LMNA/TRIM37/PRMT1/TET1/UBR5/DR1/KAT2B/DDB2/SMYD3/SNAI2/MORF4L2/RPS6KA4/CARM1/SETDB2/YEATS2/TBL1Y/CDK5/SIRT1/AKAP8/UBE2E1/PRMT3/BAP1/TET3/RBBP5/MSL1/GATA3/PRDM13/PRKCD/IWS1/SETMAR/SETD5/TAF6L/PER1/RLF/GTF3C4/MSL3/SIN3B/TBL1XR1/UIMC1/ZNF451/SMARCAD1/EYA2/TADA3/SIRT6/ARID4A/PHF10	59
BP	GO:0007622	rhythmic behavior	7/2306	47/18670	0.36	0.583	0.4486	CSF2/ID2/ADORA2A/ADA/SRD5A1/ZFHX3/ADORA1	7
BP	GO:0018198	peptidyl-cysteine modification	7/2306	47/18670	0.36	0.583	0.4486	NCOA7/ADH5/CLIP3/SNTA1/OXR1/CHCHD4/ZDHHC18	7
BP	GO:0043303	mast cell degranulation	7/2306	47/18670	0.36	0.583	0.4486	KIT/PIK3CD/IL4R/SNX4/STXBP1/VAMP7/NPPA	7
BP	GO:0048066	developmental pigmentation	7/2306	47/18670	0.36	0.583	0.4486	KIT/RAB38/ENPP1/MITF/MEF2C/RAB32/ANKRD27	7
BP	GO:0051181	cofactor transport	7/2306	47/18670	0.36	0.583	0.4486	SLC7A11/FLVCR2/PPT1/ABCC1/SLC25A20/SLC19A1/P2RX7	7
BP	GO:0061383	trabecula morphogenesis	7/2306	47/18670	0.36	0.583	0.4486	COL1A1/MSX2/SEMA4D/TGFB2/FKBP1A/ENG/UBE4B	7
BP	GO:0120163	negative regulation of cold-induced thermogenesis	7/2306	47/18670	0.36	0.583	0.4486	NPR3/IL18R1/IL15/ARNTL/ARRDC3/TFE3/LGR4	7
BP	GO:0009746	response to hexose	27/2306	202/18670	0.3607	0.5831	0.4487	ICAM1/NAMPT/PTGS2/ENSA/ERN1/PPARGC1A/GJD3/GIP/CYBA/THBS1/TCF7L2/RAB11FIP2/LRP5/ATG7/KCNB1/SESN2/DYNLL1/BRSK2/EIF2B5/EIF2B4/GYS2/PPP3CA/PDK3/GAS6/SRI/RMI1/ADRA2A	27
BP	GO:0033006	regulation of mast cell activation involved in immune response	5/2306	32/18670	0.3609	0.5831	0.4487	IL4R/SNX4/STXBP1/VAMP7/NPPA	5
BP	GO:0042573	retinoic acid metabolic process	5/2306	32/18670	0.3609	0.5831	0.4487	ALDH1A3/CYP27C1/RDH10/ADH1C/CYP2S1	5
BP	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	5/2306	32/18670	0.3609	0.5831	0.4487	KIT/FGF2/PDGFRB/IRS1/TNFAIP8L3	5
BP	GO:0045589	regulation of regulatory T cell differentiation	5/2306	32/18670	0.3609	0.5831	0.4487	IRF1/SOCS1/HLA-G/DUSP10/CBFB	5
BP	GO:0045922	negative regulation of fatty acid metabolic process	5/2306	32/18670	0.3609	0.5831	0.4487	INSIG2/ACACB/TRIB3/SIRT1/APPL2	5
BP	GO:0048841	regulation of axon extension involved in axon guidance	5/2306	32/18670	0.3609	0.5831	0.4487	VEGFA/BMPR2/SEMA4D/WNT5A/SEMA4F	5
BP	GO:0070207	protein homotrimerization	5/2306	32/18670	0.3609	0.5831	0.4487	TRAF2/P2RX3/MLKL/HLA-G/SIGMAR1	5
BP	GO:0071353	cellular response to interleukin-4	5/2306	32/18670	0.3609	0.5831	0.4487	PARP14/IL4R/STAT6/IMPDH2/GATA3	5
BP	GO:0000045	autophagosome assembly	13/2306	93/18670	0.3612	0.5835	0.4489	RAB23/GABARAPL1/TP53INP2/CHMP4B/WIPI1/RAB3GAP1/TP53INP1/RNF5/ATG7/WDR45/PACS2/PIP4K2A/FEZ2	13
BP	GO:0070988	demethylation	10/2306	70/18670	0.3626	0.5855	0.4505	JARID2/APOBEC3G/FTO/TET1/APOBEC3H/CYP1A2/TET3/GATA3/APOBEC3F/USP9X	10
BP	GO:0008361	regulation of cell size	24/2306	179/18670	0.3659	0.5908	0.4545	KCNN4/NTN1/IL7R/ZFYVE27/DBN1/VEGFA/PAK1/BMPR2/RUFY3/SLC12A2/EDN1/RDX/SEMA4D/IFRD1/CDK5/WNT5A/TMEM123/CLN8/GDI1/RTN4/ABL1/SEMA4F/CDH4/P2RX7	24
BP	GO:0042737	drug catabolic process	19/2306	140/18670	0.3669	0.5922	0.4556	CYP4B1/NAGK/CYP2U1/IL4I1/AMPD3/SMOX/FAH/ADA/ACAT1/MOXD1/CYP1A2/AADAT/SULT1C4/AMT/HBB/PDXP/FMO4/CYP2C19/CYP2S1	19
BP	GO:0006487	protein N-linked glycosylation	11/2306	78/18670	0.3679	0.5932	0.4564	GFPT2/ST3GAL1/MAN1C1/MOGS/PGM3/MGAT1/MGAT2/ALG3/DAD1/ALG13/TMEM165	11
BP	GO:0008306	associative learning	11/2306	78/18670	0.3679	0.5932	0.4564	KIT/SLC7A11/PPT1/MAP1A/ADCY3/CDK5/BTG2/CLN8/NPTN/ACTR2/RIN1	11
BP	GO:0031016	pancreas development	11/2306	78/18670	0.3679	0.5932	0.4564	IL6/CDK6/FOXO1/GIP/BMP4/NEUROG3/TCF7L2/ARNTL/GATA6/WNT5A/FGF10	11
BP	GO:0003229	ventricular cardiac muscle tissue development	8/2306	55/18670	0.3681	0.5932	0.4564	ID2/RXRA/TGFB2/FKBP1A/MYH6/ENG/UBE4B/TBX3	8
BP	GO:0032613	interleukin-10 production	8/2306	55/18670	0.3681	0.5932	0.4564	CD83/TRIB2/ISG15/PDCD1LG2/IDO1/BCL3/PRKCD/SASH3	8
BP	GO:0044273	sulfur compound catabolic process	8/2306	55/18670	0.3681	0.5932	0.4564	VCAN/NUDT7/ACAT1/PCYOX1/GLB1/CHAC2/ABCD1/ADO	8
BP	GO:0043535	regulation of blood vessel endothelial cell migration	21/2306	156/18670	0.3714	0.5983	0.4603	PTGS2/HSPB1/FGF2/PRKCA/VEGFA/PLK2/CD40/RHOJ/ETS1/KLF4/THBS1/CARD10/STARD13/MEOX2/AMOTL1/MEF2C/SIRT1/MIR19B2/MIR137/ABL1/PPARG	21
BP	GO:0001942	hair follicle development	12/2306	86/18670	0.3724	0.5989	0.4607	LDB2/HOXC13/MSX2/ERCC2/TGFB2/WNT5A/TP63/TNF/FST/LGR4/FGF10/FERMT1	12
BP	GO:0001709	cell fate determination	6/2306	40/18670	0.3726	0.5989	0.4607	BMP4/KLF4/GATA6/IFRD1/MEF2C/GATA3	6
BP	GO:0051931	regulation of sensory perception	6/2306	40/18670	0.3726	0.5989	0.4607	CCL3/EDN1/F2R/ADORA1/P2RX3/NMUR2	6
BP	GO:0072583	clathrin-dependent endocytosis	6/2306	40/18670	0.3726	0.5989	0.4607	DAB2/FNBP1L/SGIP1/ITGA4/CLTC/PICALM	6
BP	GO:0002068	glandular epithelial cell development	4/2306	25/18670	0.3735	0.5989	0.4607	CDK6/BMP4/ARNTL/WNT5A	4
BP	GO:0002335	mature B cell differentiation	4/2306	25/18670	0.3735	0.5989	0.4607	POU2F2/ADA/BCL3/SLAMF8	4
BP	GO:0002719	negative regulation of cytokine production involved in immune response	4/2306	25/18670	0.3735	0.5989	0.4607	HLA-F/IRAK3/TGFB2/TNF	4
BP	GO:0007026	negative regulation of microtubule depolymerization	4/2306	25/18670	0.3735	0.5989	0.4607	MID1/TAOK1/MID1IP1/CAMSAP1	4
BP	GO:0019430	removal of superoxide radicals	4/2306	25/18670	0.3735	0.5989	0.4607	SOD2/GCH1/RGN/TNF	4
BP	GO:0021952	central nervous system projection neuron axonogenesis	4/2306	25/18670	0.3735	0.5989	0.4607	SLIT2/ADARB1/MYCBP2/NFIB	4
BP	GO:0031639	plasminogen activation	4/2306	25/18670	0.3735	0.5989	0.4607	PLAU/THBS1/SERPINE1/SERPINF2	4
BP	GO:0032461	positive regulation of protein oligomerization	4/2306	25/18670	0.3735	0.5989	0.4607	BID/MMP1/MMP3/PMAIP1	4
BP	GO:0032616	interleukin-13 production	4/2306	25/18670	0.3735	0.5989	0.4607	IL33/HLA-E/IL17RB/GATA3	4
BP	GO:0045724	positive regulation of cilium assembly	4/2306	25/18670	0.3735	0.5989	0.4607	CCDC88A/DYNLL1/MARK4/MNS1	4
BP	GO:0045830	positive regulation of isotype switching	4/2306	25/18670	0.3735	0.5989	0.4607	CD40/EXOSC6/CLCF1/STAT6	4
BP	GO:0050927	positive regulation of positive chemotaxis	4/2306	25/18670	0.3735	0.5989	0.4607	VEGFA/ITGA2/PGF/FGF10	4
BP	GO:0097186	amelogenesis	4/2306	25/18670	0.3735	0.5989	0.4607	FOXO1/MSX2/STIM1/ITGA6	4
BP	GO:2000679	positive regulation of transcription regulatory region DNA binding	4/2306	25/18670	0.3735	0.5989	0.4607	KLF4/TRIM6/GATA3/IGF1	4
BP	GO:0006805	xenobiotic metabolic process	17/2306	125/18670	0.3744	0.6003	0.4618	CBR3/ARNT2/AHR/CMBL/GSTO1/GSTA4/CYP2U1/BPHL/GHR/CRYZ/CYP1A2/CYB5B/PHGDH/PTGS1/MGST2/CYP2C19/CYP2S1	17
BP	GO:0045815	positive regulation of gene expression, epigenetic	9/2306	63/18670	0.3746	0.6004	0.4619	TET1/SMARCA5/KAT2B/ZMIZ2/ACTB/ARID1A/ASF1A/POLR1C/MYBBP1A	9
BP	GO:0006900	vesicle budding from membrane	14/2306	102/18670	0.3796	0.6082	0.4679	FNBP1L/BET1/TGFA/MYO18A/ARF1/TMED9/TRAPPC4/TMED10/CNIH2/TRAPPC9/P2RX7/SERPINA1/PICALM/SNX3	14
BP	GO:0006473	protein acetylation	27/2306	204/18670	0.381	0.6097	0.4691	IL1B/LIF/BRPF3/PPARGC1A/FOXO1/AUTS2/SET/ARNTL/DR1/KAT2B/SNAI2/MORF4L2/RPS6KA4/YEATS2/SIRT1/MSL1/GATA3/IWS1/SETD5/TAF6L/PER1/GTF3C4/MSL3/TAOK1/ZNF451/TADA3/PHF10	27
BP	GO:0001774	microglial cell activation	7/2306	48/18670	0.3812	0.6097	0.4691	NAMPT/IL6/IL33/IFNGR1/CCL3/TNF/TLR3	7
BP	GO:0002269	leukocyte activation involved in inflammatory response	7/2306	48/18670	0.3812	0.6097	0.4691	NAMPT/IL6/IL33/IFNGR1/CCL3/TNF/TLR3	7
BP	GO:0002279	mast cell activation involved in immune response	7/2306	48/18670	0.3812	0.6097	0.4691	KIT/PIK3CD/IL4R/SNX4/STXBP1/VAMP7/NPPA	7
BP	GO:0045912	negative regulation of carbohydrate metabolic process	7/2306	48/18670	0.3812	0.6097	0.4691	PPARGC1A/COX11/ENPP1/CLTC/SIK1/STAT3/SIRT6	7
BP	GO:0101023	vascular endothelial cell proliferation	7/2306	48/18670	0.3812	0.6097	0.4691	CCL2/FGF2/ITGA4/MEF2C/PPARG/STAT3/SIRT6	7
BP	GO:1905562	regulation of vascular endothelial cell proliferation	7/2306	48/18670	0.3812	0.6097	0.4691	CCL2/FGF2/ITGA4/MEF2C/PPARG/STAT3/SIRT6	7
BP	GO:0001570	vasculogenesis	11/2306	79/18670	0.3843	0.6138	0.4722	VEGFA/PDGFRB/MYO1E/ITGB8/YAP1/HAS2/JUNB/MIR1-2/FZD4/ENG/AGGF1	11
BP	GO:0031110	regulation of microtubule polymerization or depolymerization	11/2306	79/18670	0.3843	0.6138	0.4722	MID1/PAK1/STMN3/DCTN1/MAP1A/CLIP3/MAPRE2/ABL1/TAOK1/MID1IP1/CAMSAP1	11
BP	GO:0051054	positive regulation of DNA metabolic process	30/2306	228/18670	0.3844	0.6138	0.4722	IL6/PPARGC1A/FGF2/EREG/PDGFRB/NPAS2/CD40/KLF4/FMN2/EXOSC6/ERCC2/CLCF1/STAT6/POT1/PARP9/GNL3/ATF1/SIRT1/PRKCD/MMS19/SETMAR/ACTR2/FGF10/RFC2/USP9X/UIMC1/EYA2/SIRT6/ST20/NPM2	30
BP	GO:0002717	positive regulation of natural killer cell mediated immunity	5/2306	33/18670	0.3867	0.6138	0.4722	HLA-E/IL12A/HLA-F/MICB/HLA-G	5
BP	GO:0006370	7-methylguanosine mRNA capping	5/2306	33/18670	0.3867	0.6138	0.4722	ERCC2/GTF2H5/MNAT1/GTF2F2/CDK7	5
BP	GO:0014072	response to isoquinoline alkaloid	5/2306	33/18670	0.3867	0.6138	0.4722	FADD/ADA/PPP1R9B/RGS4/ATG7	5
BP	GO:0036314	response to sterol	5/2306	33/18670	0.3867	0.6138	0.4722	ABCA1/NFE2L1/CCL3/OSBPL7/GRAMD1A	5
BP	GO:0042339	keratan sulfate metabolic process	5/2306	33/18670	0.3867	0.6138	0.4722	ST3GAL1/B4GALT3/GLB1/ST3GAL3/ST3GAL4	5
BP	GO:0043278	response to morphine	5/2306	33/18670	0.3867	0.6138	0.4722	FADD/ADA/PPP1R9B/RGS4/ATG7	5
BP	GO:0002098	tRNA wobble uridine modification	3/2306	18/18670	0.3872	0.6138	0.4722	ELP4/ALKBH8/TRMU	3
BP	GO:0007252	I-kappaB phosphorylation	3/2306	18/18670	0.3872	0.6138	0.4722	SIRPA/TRAF2/TLR3	3
BP	GO:0008090	retrograde axonal transport	3/2306	18/18670	0.3872	0.6138	0.4722	MAP1A/ACTR10/TMEM108	3
BP	GO:0009048	dosage compensation by inactivation of X chromosome	3/2306	18/18670	0.3872	0.6138	0.4722	YTHDC1/EIF1/RBM15	3
BP	GO:0009312	oligosaccharide biosynthetic process	3/2306	18/18670	0.3872	0.6138	0.4722	SLC2A1/MGAT2/ST3GAL4	3
BP	GO:0015865	purine nucleotide transport	3/2306	18/18670	0.3872	0.6138	0.4722	SLC25A24/ABCD1/ABCC11	3
BP	GO:0021756	striatum development	3/2306	18/18670	0.3872	0.6138	0.4722	SLC7A11/ALDH1A3/BBS2	3
BP	GO:0031293	membrane protein intracellular domain proteolysis	3/2306	18/18670	0.3872	0.6138	0.4722	NFKB1/APH1B/PSENEN	3
BP	GO:0031468	nuclear envelope reassembly	3/2306	18/18670	0.3872	0.6138	0.4722	CHMP4B/LMNA/ANKLE2	3
BP	GO:0032693	negative regulation of interleukin-10 production	3/2306	18/18670	0.3872	0.6138	0.4722	TRIB2/PDCD1LG2/IDO1	3
BP	GO:0034199	activation of protein kinase A activity	3/2306	18/18670	0.3872	0.6138	0.4722	ADCY7/ADCY9/ADCY3	3
BP	GO:0036166	phenotypic switching	3/2306	18/18670	0.3872	0.6138	0.4722	SOD2/MIR1-2/MIR214	3
BP	GO:0039692	single stranded viral RNA replication via double stranded DNA intermediate	3/2306	18/18670	0.3872	0.6138	0.4722	APOBEC3G/APOBEC3H/APOBEC3F	3
BP	GO:0042772	DNA damage response, signal transduction resulting in transcription	3/2306	18/18670	0.3872	0.6138	0.4722	HIPK2/SP100/CDKN1A	3
BP	GO:0045056	transcytosis	3/2306	18/18670	0.3872	0.6138	0.4722	CLTC/VPS35/PICALM	3
BP	GO:0045780	positive regulation of bone resorption	3/2306	18/18670	0.3872	0.6138	0.4722	PRKCA/TMEM64/ADAM8	3
BP	GO:0046852	positive regulation of bone remodeling	3/2306	18/18670	0.3872	0.6138	0.4722	PRKCA/TMEM64/ADAM8	3
BP	GO:0048339	paraxial mesoderm development	3/2306	18/18670	0.3872	0.6138	0.4722	NUP133/YAP1/WNT5A	3
BP	GO:0051895	negative regulation of focal adhesion assembly	3/2306	18/18670	0.3872	0.6138	0.4722	CORO1C/THBS1/PHLDB2	3
BP	GO:0070633	transepithelial transport	3/2306	18/18670	0.3872	0.6138	0.4722	CSF2/SLC12A2/EDN1	3
BP	GO:0070875	positive regulation of glycogen metabolic process	3/2306	18/18670	0.3872	0.6138	0.4722	IRS1/DYRK2/IGF1	3
BP	GO:0072077	renal vesicle morphogenesis	3/2306	18/18670	0.3872	0.6138	0.4722	LIF/STAT1/BMP4	3
BP	GO:1900221	regulation of amyloid-beta clearance	3/2306	18/18670	0.3872	0.6138	0.4722	IFNGR1/ROCK1/TNF	3
BP	GO:2000479	regulation of cAMP-dependent protein kinase activity	3/2306	18/18670	0.3872	0.6138	0.4722	SIRT1/SESN2/PKIG	3
BP	GO:2000647	negative regulation of stem cell proliferation	3/2306	18/18670	0.3872	0.6138	0.4722	SNAI2/MIR137/FERMT1	3
BP	GO:2000757	negative regulation of peptidyl-lysine acetylation	3/2306	18/18670	0.3872	0.6138	0.4722	SET/SIRT1/ZNF451	3
BP	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	8/2306	56/18670	0.3878	0.6142	0.4725	PLK2/PRMT1/CARM1/BTG2/ARID3A/CNOT8/CDKN1A/TFDP1	8
BP	GO:0051568	histone H3-K4 methylation	8/2306	56/18670	0.3878	0.6142	0.4725	AUTS2/MYB/TET3/RBBP5/GATA3/SETMAR/RLF/ARID4A	8
BP	GO:1902017	regulation of cilium assembly	8/2306	56/18670	0.3878	0.6142	0.4725	CCDC88A/CYLD/DYNC2LI1/TCHP/EVI5L/DYNLL1/MARK4/MNS1	8
BP	GO:0019362	pyridine nucleotide metabolic process	25/2306	189/18670	0.3889	0.6156	0.4736	NAMPT/PTGS2/PPARGC1A/SLC2A6/GPD1L/KYNU/IDO1/HK2/ENO2/ADPGK/NUP133/IDH1/PGM2L1/NNMT/PARP9/LDHB/PDHB/ME1/PGAM4/NUP35/IGF1/STAT3/ALDOC/P2RX7/SIRT6	25
BP	GO:0046496	nicotinamide nucleotide metabolic process	25/2306	189/18670	0.3889	0.6156	0.4736	NAMPT/PTGS2/PPARGC1A/SLC2A6/GPD1L/KYNU/IDO1/HK2/ENO2/ADPGK/NUP133/IDH1/PGM2L1/NNMT/PARP9/LDHB/PDHB/ME1/PGAM4/NUP35/IGF1/STAT3/ALDOC/P2RX7/SIRT6	25
BP	GO:0043588	skin development	54/2306	419/18670	0.3901	0.6173	0.4749	CLDN1/EREG/ROCK1/KRT14/LDB2/KRTAP1-5/COL1A1/HOXC13/KRTAP1-3/UGCG/PI3/ZFP36/MSX2/STK4/KRT16/CYP27B1/KRTAP4-1/COL5A2/ERCC2/TGFB2/ITGA2/ERRFI1/YAP1/FLNB/KRT24/KRT82/VDR/WNT5A/ARRDC3/KRT2/TP63/TNF/SPINK6/KRTAP10-12/ATP8A2/PKP4/KRT19/FST/LGR4/IVL/COL1A2/ROCK2/KRTAP4-8/KRTAP19-4/FGF10/FLG/PALLD/FERMT1/ITGA6/COL5A1/KRT80/LCE6A/KRT79/CBFB	54
BP	GO:0097711	ciliary basal body-plasma membrane docking	13/2306	95/18670	0.3913	0.619	0.4763	AHI1/DCTN1/CSNK1E/CEP290/CEP250/OFD1/CEP78/DYNLL1/TMEM216/MARK4/DCTN3/CEP63/NPHP1	13
BP	GO:0009895	negative regulation of catabolic process	40/2306	308/18670	0.3919	0.6199	0.477	NAMPT/IL1B/PPARGC1A/ROCK1/ACACB/IRAK3/FYN/CHMP4B/NRBP2/ZFP36/FMN2/SDCBP/HNRNPA0/HIPK2/MAP1A/RNF5/PABPC1/ADORA1/ATG7/VPS35/RGN/TIMP4/UBXN1/TNF/USP14/SYNCRIP/POLDIP2/PDE3B/ANGEL2/FEZ2/ATP13A2/MIR199A2/STAT3/MYCBP2/SF3B3/SIRT6/PSMF1/ADRA2A/CRTC3/SNX3	40
BP	GO:1903672	positive regulation of sprouting angiogenesis	9/2306	64/18670	0.393	0.6208	0.4776	PTGS2/FGF2/VEGFA/PLK2/RHOJ/KLF4/BMPER/MIR1-2/ABL1	9
BP	GO:0034249	negative regulation of cellular amide metabolic process	30/2306	229/18670	0.3941	0.6208	0.4776	ZC3H12A/DAPK1/CAPRIN1/ROCK1/MOV10/FTO/ENC1/ZFP36/EIF2AK4/ZFP36L2/PRG3/RGS2/MIR19B2/BTG2/SAMD4B/SESN2/EIF3E/PUS7/MIR1-2/MIR125B1/CNOT8/MIR298/SYNCRIP/ROCK2/FXR2/ZNF540/IGF1/MRPL13/MIR218-1/STAT3	30
BP	GO:0009132	nucleoside diphosphate metabolic process	21/2306	158/18670	0.3946	0.6208	0.4776	PPARGC1A/SLC2A6/HK2/ENO2/ADPGK/CMPK2/NUP133/AK1/AMPD3/PGM2L1/NUDT18/NUDT7/NME5/GUK1/PGAM4/NUP35/IGF1/STAT3/ALDOC/P2RX7/SIRT6	21
BP	GO:0019432	triglyceride biosynthetic process	6/2306	41/18670	0.3958	0.6208	0.4776	GK/LPIN1/C3/RGN/GPAM/SIK1	6
BP	GO:0019985	translesion synthesis	6/2306	41/18670	0.3958	0.6208	0.4776	UBE2L6/ISG15/RPA2/TRIM25/UBB/RFC2	6
BP	GO:0070317	negative regulation of G0 to G1 transition	6/2306	41/18670	0.3958	0.6208	0.4776	E2F6/HLA-G/MAX/TFDP1/PHC3/FOXO4	6
BP	GO:0031623	receptor internalization	15/2306	111/18670	0.3965	0.6208	0.4776	AHI1/VEGFA/EPS15/ANKRD13A/MKLN1/CLTC/SDCBP/FLOT1/RAMP1/ARF1/DLG4/MIR199A2/RAB31/NEDD4/PICALM	15
BP	GO:0007368	determination of left/right symmetry	16/2306	119/18670	0.3986	0.6208	0.4776	RTTN/AHI1/CITED2/PKD2/DYNC2LI1/DAAM2/SETDB2/MEF2C/OFD1/WNT5A/C9orf116/ENG/FGF10/MIB1/GALNT11/TBX3	16
BP	GO:0000185	activation of MAPKKK activity	2/2306	11/18670	0.402	0.6208	0.4776	GADD45G/TNF	2
BP	GO:0001731	formation of translation preinitiation complex	2/2306	11/18670	0.402	0.6208	0.4776	DENR/EIF2S2	2
BP	GO:0001767	establishment of lymphocyte polarity	2/2306	11/18670	0.402	0.6208	0.4776	GSN/MYH9	2
BP	GO:0001976	neurological system process involved in regulation of systemic arterial blood pressure	2/2306	11/18670	0.402	0.6208	0.4776	SOD2/NAV2	2
BP	GO:0002328	pro-B cell differentiation	2/2306	11/18670	0.402	0.6208	0.4776	FNIP1/HES5	2
BP	GO:0002517	T cell tolerance induction	2/2306	11/18670	0.402	0.6208	0.4776	IDO1/HLA-G	2
BP	GO:0003264	regulation of cardioblast proliferation	2/2306	11/18670	0.402	0.6208	0.4776	SIX1/PIM1	2
BP	GO:0006054	N-acetylneuraminate metabolic process	2/2306	11/18670	0.402	0.6208	0.4776	ST3GAL1/NAGK	2
BP	GO:0006182	cGMP biosynthetic process	2/2306	11/18670	0.402	0.6208	0.4776	NPR2/NPPA	2
BP	GO:0006183	GTP biosynthetic process	2/2306	11/18670	0.402	0.6208	0.4776	NME5/IMPDH2	2
BP	GO:0006558	L-phenylalanine metabolic process	2/2306	11/18670	0.402	0.6208	0.4776	IL4I1/FAH	2
BP	GO:0006559	L-phenylalanine catabolic process	2/2306	11/18670	0.402	0.6208	0.4776	IL4I1/FAH	2
BP	GO:0006702	androgen biosynthetic process	2/2306	11/18670	0.402	0.6208	0.4776	SRD5A1/HSD17B6	2
BP	GO:0007256	activation of JNKK activity	2/2306	11/18670	0.402	0.6208	0.4776	RIPK2/MLKL	2
BP	GO:0009113	purine nucleobase biosynthetic process	2/2306	11/18670	0.402	0.6208	0.4776	PRPS1/ADA	2
BP	GO:0009125	nucleoside monophosphate catabolic process	2/2306	11/18670	0.402	0.6208	0.4776	AMPD3/NUDT11	2
BP	GO:0009629	response to gravity	2/2306	11/18670	0.402	0.6208	0.4776	BGLAP/SPARC	2
BP	GO:0014883	transition between fast and slow fiber	2/2306	11/18670	0.402	0.6208	0.4776	ATP2A2/PPP3CA	2
BP	GO:0015791	polyol transport	2/2306	11/18670	0.402	0.6208	0.4776	AQP9/AQP7	2
BP	GO:0016264	gap junction assembly	2/2306	11/18670	0.402	0.6208	0.4776	GJD3/GJB2	2
BP	GO:0018095	protein polyglutamylation	2/2306	11/18670	0.402	0.6208	0.4776	TTLL1/TTLL4	2
BP	GO:0021561	facial nerve development	2/2306	11/18670	0.402	0.6208	0.4776	SIX1/ADARB1	2
BP	GO:0021610	facial nerve morphogenesis	2/2306	11/18670	0.402	0.6208	0.4776	SIX1/ADARB1	2
BP	GO:0030241	skeletal muscle myosin thick filament assembly	2/2306	11/18670	0.402	0.6208	0.4776	MYOM1/MYOM3	2
BP	GO:0032908	regulation of transforming growth factor beta1 production	2/2306	11/18670	0.402	0.6208	0.4776	THBS1/GATA6	2
BP	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway	2/2306	11/18670	0.402	0.6208	0.4776	PAK1/YAP1	2
BP	GO:0033235	positive regulation of protein sumoylation	2/2306	11/18670	0.402	0.6208	0.4776	GNL3/PIAS3	2
BP	GO:0033860	regulation of NAD(P)H oxidase activity	2/2306	11/18670	0.402	0.6208	0.4776	CYBA/SLAMF8	2
BP	GO:0034379	very-low-density lipoprotein particle assembly	2/2306	11/18670	0.402	0.6208	0.4776	SOAT1/ARF1	2
BP	GO:0035542	regulation of SNARE complex assembly	2/2306	11/18670	0.402	0.6208	0.4776	STXBP1/ANKRD27	2
BP	GO:0036462	TRAIL-activated apoptotic signaling pathway	2/2306	11/18670	0.402	0.6208	0.4776	FADD/TNFRSF10B	2
BP	GO:0039532	negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway	2/2306	11/18670	0.402	0.6208	0.4776	TSPAN6/DHX58	2
BP	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress	2/2306	11/18670	0.402	0.6208	0.4776	EPAS1/SESN2	2
BP	GO:0045793	positive regulation of cell size	2/2306	11/18670	0.402	0.6208	0.4776	EDN1/TMEM123	2
BP	GO:0046007	negative regulation of activated T cell proliferation	2/2306	11/18670	0.402	0.6208	0.4776	PDCD1LG2/LRRC32	2
BP	GO:0046348	amino sugar catabolic process	2/2306	11/18670	0.402	0.6208	0.4776	NAGK/MGAT1	2
BP	GO:0046689	response to mercury ion	2/2306	11/18670	0.402	0.6208	0.4776	AQP9/ABCC2	2
BP	GO:0046950	cellular ketone body metabolic process	2/2306	11/18670	0.402	0.6208	0.4776	ACAT1/BDH2	2
BP	GO:0048096	chromatin-mediated maintenance of transcription	2/2306	11/18670	0.402	0.6208	0.4776	ZMIZ2/ARID1A	2
BP	GO:0051974	negative regulation of telomerase activity	2/2306	11/18670	0.402	0.6208	0.4776	POT1/PPARG	2
BP	GO:0055015	ventricular cardiac muscle cell development	2/2306	11/18670	0.402	0.6208	0.4776	LMNA/MYH10	2
BP	GO:0060159	regulation of dopamine receptor signaling pathway	2/2306	11/18670	0.402	0.6208	0.4776	RGS4/VPS35	2
BP	GO:0060439	trachea morphogenesis	2/2306	11/18670	0.402	0.6208	0.4776	BMP4/RSPO2	2
BP	GO:0060525	prostate glandular acinus development	2/2306	11/18670	0.402	0.6208	0.4776	RXRA/TP63	2
BP	GO:0061314	Notch signaling involved in heart development	2/2306	11/18670	0.402	0.6208	0.4776	SNAI2/GALNT11	2
BP	GO:0070213	protein auto-ADP-ribosylation	2/2306	11/18670	0.402	0.6208	0.4776	PARP12/PARP11	2
BP	GO:0070278	extracellular matrix constituent secretion	2/2306	11/18670	0.402	0.6208	0.4776	TNFRSF1B/ENG	2
BP	GO:0070471	uterine smooth muscle contraction	2/2306	11/18670	0.402	0.6208	0.4776	OXTR/ABAT	2
BP	GO:0071688	striated muscle myosin thick filament assembly	2/2306	11/18670	0.402	0.6208	0.4776	MYOM1/MYOM3	2
BP	GO:0072173	metanephric tubule morphogenesis	2/2306	11/18670	0.402	0.6208	0.4776	HES5/LGR4	2
BP	GO:0072611	interleukin-13 secretion	2/2306	11/18670	0.402	0.6208	0.4776	IL17RB/GATA3	2
BP	GO:0086023	adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process	2/2306	11/18670	0.402	0.6208	0.4776	PDE4D/MIR1-2	2
BP	GO:0090193	positive regulation of glomerulus development	2/2306	11/18670	0.402	0.6208	0.4776	CFLAR/PDGFD	2
BP	GO:0098814	spontaneous synaptic transmission	2/2306	11/18670	0.402	0.6208	0.4776	RPH3A/SYT1	2
BP	GO:0098883	synapse pruning	2/2306	11/18670	0.402	0.6208	0.4776	C3/CDK5	2
BP	GO:0098887	neurotransmitter receptor transport, endosome to postsynaptic membrane	2/2306	11/18670	0.402	0.6208	0.4776	VPS35/GRIPAP1	2
BP	GO:0099639	neurotransmitter receptor transport, endosome to plasma membrane	2/2306	11/18670	0.402	0.6208	0.4776	VPS35/GRIPAP1	2
BP	GO:0106072	negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	2/2306	11/18670	0.402	0.6208	0.4776	ARRDC3/MRAP2	2
BP	GO:1900112	regulation of histone H3-K9 trimethylation	2/2306	11/18670	0.402	0.6208	0.4776	LMNA/SIRT1	2
BP	GO:1901569	fatty acid derivative catabolic process	2/2306	11/18670	0.402	0.6208	0.4776	ACAT1/ABCD1	2
BP	GO:1901894	regulation of calcium-transporting ATPase activity	2/2306	11/18670	0.402	0.6208	0.4776	THADA/RGN	2
BP	GO:1902221	erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process	2/2306	11/18670	0.402	0.6208	0.4776	IL4I1/FAH	2
BP	GO:1902222	erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process	2/2306	11/18670	0.402	0.6208	0.4776	IL4I1/FAH	2
BP	GO:1902805	positive regulation of synaptic vesicle transport	2/2306	11/18670	0.402	0.6208	0.4776	CDK5/SYT1	2
BP	GO:1902946	protein localization to early endosome	2/2306	11/18670	0.402	0.6208	0.4776	RDX/ROCK2	2
BP	GO:1903011	negative regulation of bone development	2/2306	11/18670	0.402	0.6208	0.4776	RGN/FBN1	2
BP	GO:1903299	regulation of hexokinase activity	2/2306	11/18670	0.402	0.6208	0.4776	COX11/DUSP12	2
BP	GO:1904321	response to forskolin	2/2306	11/18670	0.402	0.6208	0.4776	AHR/ADCY3	2
BP	GO:1904322	cellular response to forskolin	2/2306	11/18670	0.402	0.6208	0.4776	AHR/ADCY3	2
BP	GO:1905146	lysosomal protein catabolic process	2/2306	11/18670	0.402	0.6208	0.4776	VPS35/ATP13A2	2
BP	GO:1905245	regulation of aspartic-type peptidase activity	2/2306	11/18670	0.402	0.6208	0.4776	ROCK2/PICALM	2
BP	GO:1905668	positive regulation of protein localization to endosome	2/2306	11/18670	0.402	0.6208	0.4776	RDX/ROCK2	2
BP	GO:2000615	regulation of histone H3-K9 acetylation	2/2306	11/18670	0.402	0.6208	0.4776	GATA3/ZNF451	2
BP	GO:2000786	positive regulation of autophagosome assembly	2/2306	11/18670	0.402	0.6208	0.4776	RAB3GAP1/PIP4K2A	2
BP	GO:0002448	mast cell mediated immunity	7/2306	49/18670	0.4024	0.6208	0.4776	KIT/PIK3CD/IL4R/SNX4/STXBP1/VAMP7/NPPA	7
BP	GO:0002686	negative regulation of leukocyte migration	7/2306	49/18670	0.4024	0.6208	0.4776	IL33/CCL2/SLIT2/ADA/ADORA1/SLAMF8/CYP19A1	7
BP	GO:0034260	negative regulation of GTPase activity	7/2306	49/18670	0.4024	0.6208	0.4776	FICD/SLIT2/RDX/SH3BP4/SPRY1/RGN/DGKI	7
BP	GO:0035094	response to nicotine	7/2306	49/18670	0.4024	0.6208	0.4776	VCAM1/NFKB1/SLC7A11/EDN1/ABAT/TNF/CHRNB1	7
BP	GO:1990090	cellular response to nerve growth factor stimulus	7/2306	49/18670	0.4024	0.6208	0.4776	EEF2K/SORT1/KIDINS220/MICALL1/EHD1/ARF6/TMEM108	7
BP	GO:0001835	blastocyst hatching	4/2306	26/18670	0.4029	0.6208	0.4776	PPP4R4/STMN3/AKAP3/TBL1XR1	4
BP	GO:0002360	T cell lineage commitment	4/2306	26/18670	0.4029	0.6208	0.4776	IL6/CYLD/STAT6/STAT3	4
BP	GO:0006700	C21-steroid hormone biosynthetic process	4/2306	26/18670	0.4029	0.6208	0.4776	BMP2/AKR1B1/PPARGC1A/STARD3NL	4
BP	GO:0030206	chondroitin sulfate biosynthetic process	4/2306	26/18670	0.4029	0.6208	0.4776	VCAN/CHST7/CSGALNACT1/CSGALNACT2	4
BP	GO:0030318	melanocyte differentiation	4/2306	26/18670	0.4029	0.6208	0.4776	KIT/ENPP1/MITF/MEF2C	4
BP	GO:0032957	inositol trisphosphate metabolic process	4/2306	26/18670	0.4029	0.6208	0.4776	PLCD3/PLCE1/PLCD1/PLCB4	4
BP	GO:0034453	microtubule anchoring	4/2306	26/18670	0.4029	0.6208	0.4776	GCC2/DCTN1/HOOK3/BICD2	4
BP	GO:0035188	hatching	4/2306	26/18670	0.4029	0.6208	0.4776	PPP4R4/STMN3/AKAP3/TBL1XR1	4
BP	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway	4/2306	26/18670	0.4029	0.6208	0.4776	BMP2/NKX3-1/MIR1-2/IGF1	4
BP	GO:0048596	embryonic camera-type eye morphogenesis	4/2306	26/18670	0.4029	0.6208	0.4776	ALDH1A3/HIPK2/WNT5A/ARID1A	4
BP	GO:0050926	regulation of positive chemotaxis	4/2306	26/18670	0.4029	0.6208	0.4776	VEGFA/ITGA2/PGF/FGF10	4
BP	GO:0071684	organism emergence from protective structure	4/2306	26/18670	0.4029	0.6208	0.4776	PPP4R4/STMN3/AKAP3/TBL1XR1	4
BP	GO:0072539	T-helper 17 cell differentiation	4/2306	26/18670	0.4029	0.6208	0.4776	NFKBIZ/ZC3H12A/IL6/STAT3	4
BP	GO:0099560	synaptic membrane adhesion	4/2306	26/18670	0.4029	0.6208	0.4776	GPC4/FLRT3/LRFN4/PCDH17	4
BP	GO:0099632	protein transport within plasma membrane	4/2306	26/18670	0.4029	0.6208	0.4776	STX3/SNAP47/VPS35/GRIPAP1	4
BP	GO:0099637	neurotransmitter receptor transport	4/2306	26/18670	0.4029	0.6208	0.4776	STX3/SNAP47/VPS35/GRIPAP1	4
BP	GO:1905048	regulation of metallopeptidase activity	4/2306	26/18670	0.4029	0.6208	0.4776	RECK/MBP/STAT3/PICALM	4
BP	GO:0030900	forebrain development	49/2306	381/18670	0.4034	0.6213	0.478	BMP2/ID2/CDK6/PPARGC1A/GDPD5/PITX1/SLC2A1/SLC7A11/ALDH1A3/SLC38A2/BMP4/LAMB1/FYN/SLIT2/ETS1/NR2F2/NEUROG3/OXTR/LHX8/SRD5A1/RAB3GAP1/DIXDC1/LPAR1/BBS2/ZDHHC16/AXL/ROBO1/CDK5/WNT5A/BTG2/HES5/HOOK3/NUMBL/EIF2B5/TACC2/RTN4/EXT1/ARID1A/UBB/FGF10/TRAPPC9/MYH10/MYO1D/TMEM108/DCLK2/CRKL/AKNA/TBX3/NFIB	49
BP	GO:0070125	mitochondrial translational elongation	12/2306	88/18670	0.4038	0.6217	0.4783	MRPS24/MRPS35/GFM1/MRPS9/MRPL1/MRPS18C/MRPL24/MRPL14/MRPL3/MRPL13/MRPL17/MRPL48	12
BP	GO:0098773	skin epidermis development	12/2306	88/18670	0.4038	0.6217	0.4783	LDB2/HOXC13/MSX2/ERCC2/TGFB2/WNT5A/TP63/TNF/FST/LGR4/FGF10/FERMT1	12
BP	GO:0051052	regulation of DNA metabolic process	55/2306	429/18670	0.4046	0.6228	0.4792	IL6/PPARGC1A/FGF2/IL7R/EREG/PDGFRB/NPAS2/RPA2/CD40/BMPR2/KLF4/CCDC88A/FMN2/EXOSC6/TET1/UBR5/ERCC2/CLCF1/PPP4C/STAT6/POT1/S100A11/PARP9/GNL3/ATF1/SIRT1/ATG7/RGN/ZNF91/GATA3/PRKCD/ZNF830/MMS19/MAGEF1/SETMAR/NUCKS1/PPARG/CDKN1A/RLF/ACTR2/KPNA2/ID3/FGF10/TFDP1/SH2B1/RFC2/USP9X/TSPYL2/UIMC1/ZSCAN4/SMARCAD1/EYA2/SIRT6/ST20/NPM2	55
BP	GO:0060249	anatomical structure homeostasis	56/2306	437/18670	0.4048	0.6229	0.4793	AKR1B1/TNFAIP3/IL6/HSPB1/CSF1/PRKCA/EPAS1/VEGFA/TP53INP2/WWTR1/LDB2/LIPA/RPA2/CHMP4B/UBASH3B/CYTL1/F2R/DCTN1/ACACA/MAP1A/TMEM64/FH/BBS2/YAP1/POT1/GNL3/NSMCE2/CDK5/PRIM2/ADORA1/RCN3/ACTB/BGLAP/CLN8/SP100/IAPP/FEN1/ZNF830/PCDH15/PTPN11/ANKRD11/TNFRSF11B/SERPINA3/ACTG1/P2RX7/RFC2/TAOK1/SASH3/ZSCAN4/ADAM8/HOMER2/SIRT6/ZNF675/TFF1/POTEF/SNX10	56
BP	GO:0007029	endoplasmic reticulum organization	8/2306	57/18670	0.4075	0.6261	0.4817	TRAM2/ZFYVE27/RAB3GAP1/RAB18/ATL1/RTN4/TMEM33/CASQ1	8
BP	GO:0019320	hexose catabolic process	8/2306	57/18670	0.4075	0.6261	0.4817	HK2/GALM/ENO2/ADPGK/PGM2L1/GLB1/LRP5/ALDOC	8
BP	GO:0051055	negative regulation of lipid biosynthetic process	8/2306	57/18670	0.4075	0.6261	0.4817	BMP2/NFKB1/INSIG2/TRIB3/CYP27B1/SNAI2/SIRT1/SIK1	8
BP	GO:0072431	signal transduction involved in mitotic G1 DNA damage checkpoint	8/2306	57/18670	0.4075	0.6261	0.4817	PLK2/PRMT1/CARM1/BTG2/ARID3A/CNOT8/CDKN1A/TFDP1	8
BP	GO:0075733	intracellular transport of virus	8/2306	57/18670	0.4075	0.6261	0.4817	NUP133/VPS37D/VPS37C/KPNA3/UBB/KPNA2/NUP35/NMT2	8
BP	GO:1902400	intracellular signal transduction involved in G1 DNA damage checkpoint	8/2306	57/18670	0.4075	0.6261	0.4817	PLK2/PRMT1/CARM1/BTG2/ARID3A/CNOT8/CDKN1A/TFDP1	8
BP	GO:0002695	negative regulation of leukocyte activation	23/2306	175/18670	0.4085	0.6275	0.4828	ZC3H12A/TNFAIP3/ID2/ADORA2A/IRF1/CEBPB/TNFRSF14/PDCD1LG2/IDO1/BMP4/IL4R/SOCS1/HLA-F/LRRC32/MAD1L1/DUSP3/AXL/HAVCR2/CNR2/HLA-G/SDC4/PDE5A/CBFB	23
BP	GO:0071478	cellular response to radiation	25/2306	191/18670	0.4102	0.63	0.4847	NAMPT/PTGS2/CALM1/NET1/CDC25A/CYBA/MAPK13/EIF2AK4/CRYAB/MC1R/RHOB/TP53INP1/DDB2/SNAI2/YAP1/SIRT1/BCL2L1/C9orf116/GATA3/GTF2H5/NUCKS1/CDKN1A/NEDD4/NMT2/ST20	25
BP	GO:0007179	transforming growth factor beta receptor signaling pathway	26/2306	199/18670	0.411	0.6303	0.4849	CITED2/DAB2/LRRC32/ITGB5/BMPR2/THBS1/PXN/SDCBP/HIPK2/TGFB2/GDF5/SIRT1/GDF15/CDKN1C/FBN1/APPL2/FERMT2/LTBP2/ZYX/COL1A2/UBB/ENG/FERMT1/USP9X/ZNF451/SMAD9	26
BP	GO:0031060	regulation of histone methylation	9/2306	65/18670	0.4115	0.6303	0.4849	JARID2/AUTS2/RNF20/MYB/LMNA/TET1/SIRT1/GATA3/IWS1	9
BP	GO:0051187	cofactor catabolic process	9/2306	65/18670	0.4115	0.6303	0.4849	CBR3/NUDT7/ACAT1/CHAC2/ABCD1/HMOX2/HBB/PDXP/ALDH1L2	9
BP	GO:0007389	pattern specification process	57/2306	446/18670	0.412	0.6303	0.4849	BMP2/RTTN/AHI1/CITED2/BASP1/MAFB/SIX1/C3/BMP4/MID1/GREM2/HOXC13/IRX3/NR2F2/BMPR2/PKD2/SHROOM3/HOXA11/SMARCD3/MSX2/DYNC2LI1/EDN1/HOXA10/HIPK2/SPRY1/HOXD9/EFNB1/MEOX2/LRP5/DAAM2/SETDB2/ROBO1/MEF2C/OFD1/WNT5A/NKX3-1/TP63/BTG2/HES5/HES3/HOXD3/GPR161/HOXA9/C9orf116/HOXB7/GRSF1/MNS1/ENG/FGF10/MIB1/OSR1/DVL2/GALNT11/BPTF/CRKL/SSBP3/TBX3	57
BP	GO:0002183	cytoplasmic translational initiation	5/2306	34/18670	0.4125	0.6303	0.4849	EIF4A2/DENR/EIF4A1/EIF3E/EIF2S2	5
BP	GO:0006536	glutamate metabolic process	5/2306	34/18670	0.4125	0.6303	0.4849	GLS/SLC7A11/GLUD1/AADAT/ALDH5A1	5
BP	GO:0009452	7-methylguanosine RNA capping	5/2306	34/18670	0.4125	0.6303	0.4849	ERCC2/GTF2H5/MNAT1/GTF2F2/CDK7	5
BP	GO:0010765	positive regulation of sodium ion transport	5/2306	34/18670	0.4125	0.6303	0.4849	CNKSR3/GPD1L/ANK3/ARF1/ACTN4	5
BP	GO:0032594	protein transport within lipid bilayer	5/2306	34/18670	0.4125	0.6303	0.4849	STX3/SNAP47/VPS35/RILPL1/GRIPAP1	5
BP	GO:0036260	RNA capping	5/2306	34/18670	0.4125	0.6303	0.4849	ERCC2/GTF2H5/MNAT1/GTF2F2/CDK7	5
BP	GO:0042533	tumor necrosis factor biosynthetic process	5/2306	34/18670	0.4125	0.6303	0.4849	HSPB1/THBS1/AKAP12/ERRFI1/BCL3	5
BP	GO:0042534	regulation of tumor necrosis factor biosynthetic process	5/2306	34/18670	0.4125	0.6303	0.4849	HSPB1/THBS1/AKAP12/ERRFI1/BCL3	5
BP	GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator	5/2306	34/18670	0.4125	0.6303	0.4849	CD44/PMAIP1/SNAI2/SIRT1/DDX5	5
BP	GO:0045066	regulatory T cell differentiation	5/2306	34/18670	0.4125	0.6303	0.4849	IRF1/SOCS1/HLA-G/DUSP10/CBFB	5
BP	GO:0048048	embryonic eye morphogenesis	5/2306	34/18670	0.4125	0.6303	0.4849	ALDH1A3/HIPK2/WNT5A/FBN1/ARID1A	5
BP	GO:0048566	embryonic digestive tract development	5/2306	34/18670	0.4125	0.6303	0.4849	ID2/ADA/TGFB2/TNF/FGF10	5
BP	GO:0070670	response to interleukin-4	5/2306	34/18670	0.4125	0.6303	0.4849	PARP14/IL4R/STAT6/IMPDH2/GATA3	5
BP	GO:0071868	cellular response to monoamine stimulus	5/2306	34/18670	0.4125	0.6303	0.4849	PDE4D/SRD5A1/ABL1/PDE4B/GNG2	5
BP	GO:0071870	cellular response to catecholamine stimulus	5/2306	34/18670	0.4125	0.6303	0.4849	PDE4D/SRD5A1/ABL1/PDE4B/GNG2	5
BP	GO:0098901	regulation of cardiac muscle cell action potential	5/2306	34/18670	0.4125	0.6303	0.4849	CAMK2D/ANK3/HCN4/ATP2A2/MIR1-2	5
BP	GO:0009855	determination of bilateral symmetry	17/2306	128/18670	0.4136	0.6319	0.4862	RTTN/AHI1/CITED2/GREM2/PKD2/DYNC2LI1/DAAM2/SETDB2/MEF2C/OFD1/WNT5A/C9orf116/ENG/FGF10/MIB1/GALNT11/TBX3	17
BP	GO:0006801	superoxide metabolic process	10/2306	73/18670	0.4147	0.6329	0.487	SOD2/CYBA/GCH1/EDN1/PRG3/NOX5/RGN/TNF/SH3PXD2B/PRKCD	10
BP	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	10/2306	73/18670	0.4147	0.6329	0.487	CXCL1/CXCL2/CXCL6/CXCL5/CXCL10/PF4V1/CXCL3/CXCL11/CXCL9/DEFB127	10
BP	GO:0072401	signal transduction involved in DNA integrity checkpoint	10/2306	73/18670	0.4147	0.6329	0.487	PLK2/PRMT1/CDC14B/CARM1/BTG2/ARID3A/CNOT8/CDKN1A/TFDP1/UIMC1	10
BP	GO:0072422	signal transduction involved in DNA damage checkpoint	10/2306	73/18670	0.4147	0.6329	0.487	PLK2/PRMT1/CDC14B/CARM1/BTG2/ARID3A/CNOT8/CDKN1A/TFDP1/UIMC1	10
BP	GO:0046939	nucleotide phosphorylation	18/2306	136/18670	0.4149	0.6332	0.4871	PPARGC1A/SLC2A6/HK2/ENO2/ADPGK/CMPK2/NUP133/AK1/PGM2L1/NME5/GUK1/PGAM4/NUP35/IGF1/STAT3/ALDOC/P2RX7/SIRT6	18
BP	GO:0006284	base-excision repair	6/2306	42/18670	0.4189	0.6389	0.4916	RPA2/POLB/FEN1/MBD4/NEIL3/SIRT6	6
BP	GO:0010677	negative regulation of cellular carbohydrate metabolic process	6/2306	42/18670	0.4189	0.6389	0.4916	PPARGC1A/COX11/ENPP1/SIK1/STAT3/SIRT6	6
BP	GO:0032465	regulation of cytokinesis	12/2306	89/18670	0.4196	0.6398	0.4922	PLK2/CALM1/CDC14B/BCL2L1/CALM2/BIRC6/PKP4/KLHL13/PDXP/ZFYVE19/PKN2/CDC42	12
BP	GO:0044773	mitotic DNA damage checkpoint	13/2306	97/18670	0.4215	0.6407	0.4929	PLK2/RPA2/CCND1/PRMT1/CARM1/BTG2/ARID3A/CNOT8/ZNF830/CDKN1A/TFDP1/TAOK1/FOXO4	13
BP	GO:0055092	sterol homeostasis	13/2306	97/18670	0.4215	0.6407	0.4929	ABCA1/LIMA1/FABP3/NFE2L1/LIPG/SOAT1/MALL/EHD1/LRP5/ABCD1/SIRT1/MIR19B2/MYLIP	13
BP	GO:0002363	alpha-beta T cell lineage commitment	3/2306	19/18670	0.4222	0.6407	0.4929	IL6/STAT6/STAT3	3
BP	GO:0002710	negative regulation of T cell mediated immunity	3/2306	19/18670	0.4222	0.6407	0.4929	IL7R/HLA-F/HLA-G	3
BP	GO:0002922	positive regulation of humoral immune response	3/2306	19/18670	0.4222	0.6407	0.4929	IL1B/C3/TNF	3
BP	GO:0006833	water transport	3/2306	19/18670	0.4222	0.6407	0.4929	AQP9/AQP7/HAS2	3
BP	GO:0007350	blastoderm segmentation	3/2306	19/18670	0.4222	0.6407	0.4929	BASP1/WNT5A/TBX3	3
BP	GO:0007625	grooming behavior	3/2306	19/18670	0.4222	0.6407	0.4929	PPT1/DLG4/NMUR2	3
BP	GO:0015669	gas transport	3/2306	19/18670	0.4222	0.6407	0.4929	CYGB/NGB/HBB	3
BP	GO:0016075	rRNA catabolic process	3/2306	19/18670	0.4222	0.6407	0.4929	EXOSC6/DEDD2/DIS3L	3
BP	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway	3/2306	19/18670	0.4222	0.6407	0.4929	IL1B/VEGFA/FGF10	3
BP	GO:0032303	regulation of icosanoid secretion	3/2306	19/18670	0.4222	0.6407	0.4929	IL1B/EDN1/P2RX7	3
BP	GO:0045076	regulation of interleukin-2 biosynthetic process	3/2306	19/18670	0.4222	0.6407	0.4929	IL1B/IL1A/ZFP36	3
BP	GO:0046112	nucleobase biosynthetic process	3/2306	19/18670	0.4222	0.6407	0.4929	PRPS1/ADA/CPS1	3
BP	GO:0046641	positive regulation of alpha-beta T cell proliferation	3/2306	19/18670	0.4222	0.6407	0.4929	RIPK2/HLA-E/EBI3	3
BP	GO:0060716	labyrinthine layer blood vessel development	3/2306	19/18670	0.4222	0.6407	0.4929	PLCD3/PLCD1/JUNB	3
BP	GO:1900409	positive regulation of cellular response to oxidative stress	3/2306	19/18670	0.4222	0.6407	0.4929	MMP3/RGN/TNF	3
BP	GO:1902644	tertiary alcohol metabolic process	3/2306	19/18670	0.4222	0.6407	0.4929	BMP2/AKR1B1/CBR4	3
BP	GO:2000251	positive regulation of actin cytoskeleton reorganization	3/2306	19/18670	0.4222	0.6407	0.4929	CDK5/ABL1/CDC42	3
BP	GO:2000831	regulation of steroid hormone secretion	3/2306	19/18670	0.4222	0.6407	0.4929	C1QTNF1/NKX3-1/PTPN11	3
BP	GO:0007611	learning or memory	33/2306	256/18670	0.4242	0.6435	0.4951	PTGS2/SLC11A2/KIT/CEBPB/SLC7A11/GIP/PLK2/FYN/OXTR/LHX8/EIF2AK4/PPT1/MAP1A/THRA/ADCY3/MEF2C/CDK5/BHLHB9/SYT4/BTG2/DGKI/CLN8/DLG4/FEN1/NPTN/GMFB/VDAC1/YTHDF1/ACTR2/TMOD2/RIN1/PJA2/PICALM	33
BP	GO:0044782	cilium organization	49/2306	384/18670	0.4262	0.6463	0.4973	RTTN/RAB23/AHI1/FNBP1L/LRRC49/TMEM138/WWTR1/TTLL1/ACTR3/PKD2/CCDC88A/TTC39C/CYLD/DYNC2LI1/WDR63/CCNO/CDC14B/DCTN1/NME5/TCHP/BBS2/TTC17/CSNK1E/EHD1/CEP290/CEP250/OFD1/EVI5L/KIF17/GSN/TTC36/CEP78/DYNLL1/TMEM216/ICK/ASAP1/SPATA6/MARK4/ACTR2/MNS1/RILPL1/DCTN3/CEP63/CCDC113/GALNT11/RSPH9/RFX2/NPHP1/SNX10	49
BP	GO:0034605	cellular response to heat	18/2306	137/18670	0.4277	0.6484	0.4989	PTGS2/CXCL10/IL1A/BAG2/ST8SIA1/DAXX/MYOF/RPA2/CAMK2D/NUP133/THBS1/CRYAB/STAC/SIRT1/CAMK2G/ATP2A2/CDKN1A/NUP35	18
BP	GO:0007612	learning	19/2306	145/18670	0.4285	0.6495	0.4997	PTGS2/KIT/SLC7A11/FYN/EIF2AK4/PPT1/MAP1A/ADCY3/CDK5/BTG2/DGKI/CLN8/DLG4/NPTN/GMFB/VDAC1/YTHDF1/ACTR2/RIN1	19
CC	GO:0005925	focal adhesion	102/2382	405/19717	1.902e-13	1.106e-10	9.412e-11	ICAM1/ITGA1/FLNC/HSPB1/NEXN/MPZL1/DAB2/ASAP3/FHL1/LMO7/LPXN/CORO1C/CNN2/PAK1/PDGFRB/VCL/ZFYVE21/PPFIA1/CDC42EP1/FZD1/LIMA1/ACTR3/PLAU/MPRIP/CD44/NEDD9/PPP1R12A/ITGB5/LIMS2/HSPG2/RPS3A/ITGA4/CYBA/FHL2/TRIP6/ACTC1/AKAP12/RDX/PXN/DIXDC1/FZD2/CLTC/SDCBP/RHOB/ITGB8/ITGA2/RPL7/RPL22/PPIA/GNA13/RSU1/IGF2R/TM4SF20/FLNB/GNA12/FLOT1/RHOU/FLRT2/ZNF185/CPNE3/CNN3/TPM4/PHLDB2/ARPC2/REXO2/PABPC1/ENAH/RPL37A/ITGA11/ARF6/ARF1/TNC/GSN/PTK7/ACTB/FLRT3/HYOU1/ACTN4/FERMT2/ARHGAP24/SDC4/MAPRE2/ZYX/STX16/RALA/PPFIBP1/ACTR2/ENG/LPP/CDC42/SNTB1/PALLD/FERMT1/MYH9/ITGA6/ACTG1/TLN1/ITGBL1/PDCD6IP/CAPN2/EPB41L2/RPS18	102
CC	GO:0005924	cell-substrate adherens junction	102/2382	408/19717	3.121e-13	1.106e-10	9.412e-11	ICAM1/ITGA1/FLNC/HSPB1/NEXN/MPZL1/DAB2/ASAP3/FHL1/LMO7/LPXN/CORO1C/CNN2/PAK1/PDGFRB/VCL/ZFYVE21/PPFIA1/CDC42EP1/FZD1/LIMA1/ACTR3/PLAU/MPRIP/CD44/NEDD9/PPP1R12A/ITGB5/LIMS2/HSPG2/RPS3A/ITGA4/CYBA/FHL2/TRIP6/ACTC1/AKAP12/RDX/PXN/DIXDC1/FZD2/CLTC/SDCBP/RHOB/ITGB8/ITGA2/RPL7/RPL22/PPIA/GNA13/RSU1/IGF2R/TM4SF20/FLNB/GNA12/FLOT1/RHOU/FLRT2/ZNF185/CPNE3/CNN3/TPM4/PHLDB2/ARPC2/REXO2/PABPC1/ENAH/RPL37A/ITGA11/ARF6/ARF1/TNC/GSN/PTK7/ACTB/FLRT3/HYOU1/ACTN4/FERMT2/ARHGAP24/SDC4/MAPRE2/ZYX/STX16/RALA/PPFIBP1/ACTR2/ENG/LPP/CDC42/SNTB1/PALLD/FERMT1/MYH9/ITGA6/ACTG1/TLN1/ITGBL1/PDCD6IP/CAPN2/EPB41L2/RPS18	102
CC	GO:0030055	cell-substrate junction	102/2382	412/19717	5.97e-13	1.411e-10	1.2e-10	ICAM1/ITGA1/FLNC/HSPB1/NEXN/MPZL1/DAB2/ASAP3/FHL1/LMO7/LPXN/CORO1C/CNN2/PAK1/PDGFRB/VCL/ZFYVE21/PPFIA1/CDC42EP1/FZD1/LIMA1/ACTR3/PLAU/MPRIP/CD44/NEDD9/PPP1R12A/ITGB5/LIMS2/HSPG2/RPS3A/ITGA4/CYBA/FHL2/TRIP6/ACTC1/AKAP12/RDX/PXN/DIXDC1/FZD2/CLTC/SDCBP/RHOB/ITGB8/ITGA2/RPL7/RPL22/PPIA/GNA13/RSU1/IGF2R/TM4SF20/FLNB/GNA12/FLOT1/RHOU/FLRT2/ZNF185/CPNE3/CNN3/TPM4/PHLDB2/ARPC2/REXO2/PABPC1/ENAH/RPL37A/ITGA11/ARF6/ARF1/TNC/GSN/PTK7/ACTB/FLRT3/HYOU1/ACTN4/FERMT2/ARHGAP24/SDC4/MAPRE2/ZYX/STX16/RALA/PPFIBP1/ACTR2/ENG/LPP/CDC42/SNTB1/PALLD/FERMT1/MYH9/ITGA6/ACTG1/TLN1/ITGBL1/PDCD6IP/CAPN2/EPB41L2/RPS18	102
CC	GO:0030027	lamellipodium	52/2382	193/19717	1.395e-08	2.472e-06	2.103e-06	SLC39A14/TUBB3/PDLIM4/SH3RF1/FSCN1/PDPN/DBN1/MCC/CORO1C/ROCK1/RAB13/PAK1/ACTR3/CD44/NEDD9/PKD2/STX3/SSH1/RUFY3/CCDC88A/PTPN13/ACTC1/RDX/PXN/DPYSL3/PODXL/PPP1R9B/PLEKHH2/FGD4/FGD1/FLOT1/AMOTL1/ARPC2/CDK5/ENAH/MYLK/GSN/TIAM2/FERMT2/PLEK2/PTPRM/PLXND1/KPTN/MYO10/PDXP/VAMP7/ACTR2/PKN2/PALLD/MYH10/RAPH1/WASF2	52
CC	GO:0031252	cell leading edge	85/2382	403/19717	1.626e-07	2.306e-05	1.961e-05	SLC39A14/CYTH3/TUBB3/PDLIM4/SH3RF1/ADORA2A/CDK6/FSCN1/ASAP3/PDPN/PSD4/DBN1/MCC/GABARAPL1/CORO1C/ROCK1/RAB13/PAK1/LDB2/LIMA1/ACTR3/WWC1/CD44/NEDD9/DDX58/MYADM/PKD2/STX3/SSH1/RUFY3/MKLN1/CCDC88A/PTPN13/ACTC1/RDX/PXN/RINL/DPYSL3/PODXL/EPB41L3/PPP1R9B/PLEKHH2/FGD4/FGD1/FLOT1/S100A11/PLEKHO1/AMOTL1/PHLDB2/ARPC2/CDK5/ENAH/ADORA1/KCNB1/ARF6/ARF1/MYLK/EPS8/GSN/APPL2/TIAM2/FERMT2/PLEK2/PTPRM/PLXND1/DIAPH1/GABRA3/KPTN/ABL1/MYO10/PDXP/KSR1/VAMP7/ACTR2/PKN2/PALLD/VEZT/FERMT1/MYH9/SH3YL1/MYH10/MYO1D/RAPH1/TLN1/WASF2	85
CC	GO:0042641	actomyosin	27/2382	79/19717	2.581e-07	3.049e-05	2.594e-05	PDLIM4/FSCN1/DBN1/CNN2/LIMA1/CYBA/TRIP6/ACTC1/PXN/ROR1/KAT2B/FHOD1/FLNB/TPM4/MYO18A/MYLK/PDLIM5/ACTN4/FERMT2/PDLIM2/ZYX/MYH6/LPP/MYH9/MYH10/PDCD6IP/PDLIM3	27
CC	GO:0005839	proteasome core complex	12/2382	20/19717	4.646e-07	4.706e-05	4.003e-05	PSMA6/PSMB10/PSMB8/PSMB7/PSMB9/PSMA3/PSMA1/PSMB2/PSMB3/PSMA8/PSMB5/PSMF1	12
CC	GO:0005911	cell-cell junction	92/2382	459/19717	5.738e-07	5.086e-05	4.326e-05	AKR1B1/CYTH3/CLDN1/PDLIM4/FSCN1/AHI1/KIT/STEAP1/GJD3/DBN1/SLC2A1/MXRA8/VEGFA/PANX1/RAB13/CNN2/PAK1/JAM3/CNTNAP1/VCL/CDC42EP1/CGNL1/ACTR3/JAM2/BMPR2/DDX58/EPB41L4B/MYADM/PKD2/CCND1/LIMS2/STX3/PANX2/ANK3/SHROOM3/TRIM29/WTIP/CLDN12/CLDN14/OXTR/MYO1E/FGFRL1/RDX/PODXL/EPB41L3/GJC2/AQP7/LIN7A/TCHP/GJB2/FHOD1/FLOT1/S100A11/FLRT2/AMOTL1/CNN3/TMEM47/ABCC2/SHROOM2/CLDN20/PTK7/PDZD2/FLRT3/PDLIM5/YWHAH/TACSTD2/ATP2A2/ACTN4/FZD4/PTPRM/PKP4/PRKCD/USP53/PDLIM2/PPP3CA/ZYX/CLDN7/MPDZ/PDXP/PKN2/TJP1/MYH9/CLDN17/CDH4/ITGA6/LIN7C/P2RX7/PDCD6IP/WASF2/VAMP5/NPHP1/PDLIM3	92
CC	GO:0030666	endocytic vesicle membrane	42/2382	167/19717	2.399e-06	0.000189	0.0001608	TAP1/TAP2/RAB23/ENTPD7/RAB9A/HLA-E/HLA-F/ATP6V0B/RAB38/EPS15/CAMK2D/ATP6V0E2/SGIP1/CYBA/HLA-A/FZD2/HBEGF/CLTC/DMBT1/NOSTRIN/GRIA3/WNT5B/WNT5A/RAB32/CAMK2G/APPL2/GPR161/FZD4/DLG4/RAB9B/INPP5B/HLA-G/HLA-DQB1/RAB11FIP1/UBB/MCOLN1/VAMP7/TAPBP/RAB31/HLA-B/HLA-H/PICALM	42
CC	GO:0002102	podosome	14/2382	30/19717	2.981e-06	0.0002113	0.0001798	VCAM1/FSCN1/LPXN/VCL/RHOU/TPM4/ARHGEF5/GSN/SH3PXD2B/ASAP1/ACTR2/TJP1/PALLD/ADAM8	14
CC	GO:0032432	actin filament bundle	24/2382	75/19717	4.435e-06	0.0002696	0.0002293	PDLIM4/PLS3/FSCN1/CNN2/LIMA1/CYBA/TRIP6/CRYAB/PXN/ROR1/FHOD1/FLNB/TPM4/MYLK/PDLIM5/ACTN4/FERMT2/PDLIM2/ZYX/MYH6/LPP/MYH9/MYH10/PDLIM3	24
CC	GO:0045335	phagocytic vesicle	35/2382	132/19717	4.563e-06	0.0002696	0.0002293	TAP1/TAP2/RAB23/ABCA1/RAB9A/ANXA11/HLA-E/HLA-F/ATP6V0B/RAB38/ITGB5/STX6/ATP6V0E2/CYBA/HLA-A/DMBT1/FLNB/RAB32/GSN/APPL2/RAB9B/STXBP1/INPP5B/HLA-G/ZYX/RAB11FIP1/MCOLN1/VAMP7/TAPBP/ACTG1/RAB31/HLA-B/HLA-H/ADAM8/SNX3	35
CC	GO:0030139	endocytic vesicle	64/2382	303/19717	5.034e-06	0.0002745	0.0002336	TAP1/TAP2/PLD1/RAB23/ABCA1/ENTPD7/RAB9A/ANXA11/RAB13/HLA-E/HLA-F/ATP6V0B/RAB38/EPS15/ITGB5/CAMK2D/STX6/ATP6V0E2/SGIP1/CYBA/HLA-A/MYO1E/FZD2/HBEGF/CLTC/DMBT1/LPAR1/NOSTRIN/GRIA3/WNT5B/IGF2R/FLNB/WNT5A/RAB32/ARF6/GSN/CAMK2G/APPL2/GPR161/HYOU1/SPARC/FZD4/DLG4/RAB9B/STXBP1/INPP5B/HLA-G/ZYX/HLA-DQB1/RAB11FIP1/HBB/RALA/UBB/MCOLN1/VAMP7/TAPBP/ACTG1/DVL2/RAB31/HLA-B/HLA-H/ADAM8/PICALM/SNX3	64
CC	GO:0030670	phagocytic vesicle membrane	24/2382	76/19717	5.745e-06	0.0002909	0.0002475	TAP1/TAP2/RAB23/RAB9A/HLA-E/HLA-F/ATP6V0B/RAB38/ATP6V0E2/CYBA/HLA-A/DMBT1/RAB32/APPL2/RAB9B/INPP5B/HLA-G/RAB11FIP1/MCOLN1/VAMP7/TAPBP/RAB31/HLA-B/HLA-H	24
CC	GO:0001725	stress fiber	22/2382	67/19717	6.864e-06	0.0003042	0.0002588	PDLIM4/FSCN1/CNN2/LIMA1/CYBA/TRIP6/PXN/ROR1/FHOD1/FLNB/TPM4/MYLK/PDLIM5/ACTN4/FERMT2/PDLIM2/ZYX/MYH6/LPP/MYH9/MYH10/PDLIM3	22
CC	GO:0097517	contractile actin filament bundle	22/2382	67/19717	6.864e-06	0.0003042	0.0002588	PDLIM4/FSCN1/CNN2/LIMA1/CYBA/TRIP6/PXN/ROR1/FHOD1/FLNB/TPM4/MYLK/PDLIM5/ACTN4/FERMT2/PDLIM2/ZYX/MYH6/LPP/MYH9/MYH10/PDLIM3	22
CC	GO:0000502	proteasome complex	21/2382	63/19717	8.467e-06	0.0003531	0.0003004	PSME2/PSMA6/HSPB1/PSMB10/PSMB8/PSMB7/PSME1/RAD23B/PSMB9/PSMA3/UBR1/PSMA1/PSMB2/PSMB3/RAD23A/USP14/PSMA8/PSME4/PSMB5/ZFAND2A/PSMF1	21
CC	GO:1905369	endopeptidase complex	21/2382	64/19717	1.118e-05	0.0004403	0.0003745	PSME2/PSMA6/HSPB1/PSMB10/PSMB8/PSMB7/PSME1/RAD23B/PSMB9/PSMA3/UBR1/PSMA1/PSMB2/PSMB3/RAD23A/USP14/PSMA8/PSME4/PSMB5/ZFAND2A/PSMF1	21
CC	GO:0030176	integral component of endoplasmic reticulum membrane	37/2382	150/19717	1.492e-05	0.0005566	0.0004735	TAP1/TAP2/ERN1/ZFYVE27/INSIG2/ESYT1/TBL2/HLA-E/ELOVL5/HLA-F/FICD/PKD2/SCD/ELOVL7/HLA-A/TM7SF2/ELOVL2/STIM1/ANKLE2/HLA-G/SGMS2/RTN4/EXT1/ALG3/HLA-DQB1/PIGK/PIGS/TAPBP/SLC35B4/SLC35B1/SLC37A1/SAMD8/HLA-B/TMEM33/HLA-H/BFAR/ELOVL3	37
CC	GO:0031227	intrinsic component of endoplasmic reticulum membrane	38/2382	158/19717	2.131e-05	0.0007554	0.0006427	TAP1/TAP2/ERN1/ZFYVE27/INSIG2/ESYT1/TBL2/HLA-E/ELOVL5/HLA-F/FICD/PKD2/SCD/ELOVL7/HLA-A/TM7SF2/ELOVL2/STIM1/ANKLE2/HLA-G/SGMS2/RTN4/EXT1/ALG3/HLA-DQB1/PIGK/PIGS/TAPBP/SLC35B4/SLC35B1/SLC37A1/SAMD8/HLA-B/TMEM33/HLA-H/BFAR/ELOVL3/GRAMD1A	38
CC	GO:0005938	cell cortex	62/2382	308/19717	3.323e-05	0.001122	0.0009544	TNFAIP2/FNBP1L/DBN1/SLC2A1/CORO1C/AGTRAP/ACTR3/CALD1/NEDD9/RHOJ/PLA2G4C/MYADM/PKD2/MKLN1/SHROOM3/FMN2/AKAP12/RDX/PXN/DSTN/GPSM2/RHOB/DCTN1/PHLDB1/PLEKHH2/AQP7/TCHP/RHOBTB3/FLNB/FLOT1/RHOU/ITPR2/TPM4/PHLDB2/TRAF2/CAPZA2/ARF6/SHROOM2/MICAL3/EPS8/GSN/ACTB/BIN3/ACTN4/FERMT2/DLG4/STIM1/CAP2/KRT19/GYS2/GMFB/MYO10/ACTR2/CDC42/MYH9/MYH10/MYO1D/PPFIA3/NEDD4/CAPN2/EPB41L2/POTEF	62
CC	GO:0030173	integral component of Golgi membrane	19/2382	60/19717	5.054e-05	0.001629	0.001386	TPST1/BET1/SYS1/MAN1C1/A4GALT/SLC35A1/CSGALNACT1/CSGALNACT2/UBIAD1/POMGNT1/QSOX2/SYT4/SGMS2/SLC35B4/STEAP2/SLC35B1/SAMD8/UNC50/RER1	19
CC	GO:0019774	proteasome core complex, beta-subunit complex	7/2382	11/19717	7.886e-05	0.002431	0.002068	PSMB10/PSMB8/PSMB7/PSMB9/PSMB2/PSMB3/PSMB5	7
CC	GO:0010008	endosome membrane	85/2382	479/19717	0.0001645	0.004765	0.004054	IRAK2/SLC11A2/PLD1/PDLIM4/RAB23/EHD4/CHMP1B/STEAP1/ZFYVE27/CORO1C/IRAK4/IRF7/RAB13/HLA-E/PLEKHF1/HLA-F/ATP6V0B/EPS15/SORT1/CHMP4B/BACE1/GRB14/SNX4/ATP6V0E2/WIPI1/ITCH/ANXA8/HLA-A/MICALL1/NDFIP1/VPS37D/CLTC/VPS36/RHOB/VPS37C/RAB11FIP2/STOML1/ABCA5/RAB4A/APH1B/EHD1/CLIP3/OPTN/ARHGAP1/VPS35/PSENEN/ARF6/TPCN1/TMEM175/APPL2/TMEM9/SCAMP4/PLEKHF2/TMEM106B/TLR3/INPP5B/HLA-G/CHMP5/WDR91/HSD17B6/HLA-DQB1/STARD3NL/SBF2/UBB/MITD1/MCOLN1/VAMP7/TM9SF2/STEAP2/NDFIP2/TICAM1/ATP13A2/TMEM108/RAB31/HLA-B/GRIPAP1/FZD7/HLA-H/VPS26A/SLC9A9/TMEM165/VPS45/SNX3/CD164/SNX10	85
CC	GO:0031228	intrinsic component of Golgi membrane	19/2382	65/19717	0.000168	0.004765	0.004054	TPST1/BET1/SYS1/MAN1C1/A4GALT/SLC35A1/CSGALNACT1/CSGALNACT2/UBIAD1/POMGNT1/QSOX2/SYT4/SGMS2/SLC35B4/STEAP2/SLC35B1/SAMD8/UNC50/RER1	19
CC	GO:1905368	peptidase complex	23/2382	89/19717	0.0002821	0.007242	0.006161	PSME2/PSMA6/HSPB1/PSMB10/PSMB8/PSMB7/PSME1/RAD23B/PSMB9/PSMA3/UBR1/PSMA1/PSMB2/PSMB3/RAD23A/USP14/PSMA8/TAF6L/PSME4/PSMB5/ZFAND2A/TADA3/PSMF1	23
CC	GO:0044449	contractile fiber part	45/2382	221/19717	0.0002873	0.007242	0.006161	AHNAK2/FLNC/PDLIM4/PSMA6/HSPB1/NEXN/SQSTM1/SLC2A1/IDO1/CORO1C/PAK1/VCL/CALM1/PPP1R12A/ANK3/FHL2/MYL5/ACTC1/CRYAB/MYOM1/KAT2B/FLNB/SYNM/TPM4/ARF1/MYOM3/TIMP4/PDLIM5/FBXL22/CALM2/ACTN4/FERMT2/FKBP1A/KCTD6/KRT19/PDLIM2/PPP3CA/SDC4/PDE4B/TMOD2/MYH6/PALLD/SRI/CASQ1/PDLIM3	45
CC	GO:0005667	transcription factor complex	67/2382	365/19717	0.0002958	0.007242	0.006161	ARNT2/PITX1/CEBPB/MEIS1/MAFB/RCOR3/SIX1/EPAS1/AHR/SIX5/WWTR1/LDB2/NPAS2/TCF12/RXRA/ETS1/KLF4/HOXA11/WTIP/RCOR2/HOXA10/TCF7L2/E2F2/ARNTL/HIPK2/ERCC2/GATA6/THRA/YAP1/ZFHX3/CARM1/ASCL2/SIX4/ATF1/VDR/JUNB/ONECUT3/E2F6/TAF13/SOX7/HOXA9/IVNS1ABP/SUB1/CEBPA/MED8/TCF7L1/TAF7L/MMS19/GTF2H5/TAF6L/ASCL3/MAX/PPARG/TLE1/MNAT1/TFDP1/GTF3C4/STAT3/POU2AF1/GTF2F2/CDK7/ARNTL2/TADA3/SSBP3/NCOA6/SMAD9/CBFB	67
CC	GO:0043292	contractile fiber	47/2382	234/19717	0.0002962	0.007242	0.006161	AHNAK2/FLNC/PDLIM4/PSMA6/HSPB1/NEXN/SQSTM1/SLC2A1/IDO1/CORO1C/PAK1/VCL/CALD1/CALM1/PPP1R12A/ANK3/FHL2/MYL5/ACTC1/CRYAB/MYOM1/KAT2B/FLNB/SYNM/TPM4/ARF1/MYOM3/TIMP4/PDLIM5/FBXL22/CALM2/ACTN4/FERMT2/FKBP1A/KCTD6/KRT19/PDLIM2/PPP3CA/SDC4/PDE4B/TMOD2/MYH6/PALLD/ACTG1/SRI/CASQ1/PDLIM3	47
CC	GO:0030016	myofibril	45/2382	224/19717	0.0003918	0.009259	0.007877	AHNAK2/FLNC/PDLIM4/PSMA6/HSPB1/NEXN/SQSTM1/SLC2A1/CORO1C/PAK1/VCL/CALD1/CALM1/PPP1R12A/ANK3/FHL2/ACTC1/CRYAB/MYOM1/KAT2B/FLNB/SYNM/TPM4/ARF1/MYOM3/TIMP4/PDLIM5/FBXL22/CALM2/ACTN4/FERMT2/FKBP1A/KCTD6/KRT19/PDLIM2/PPP3CA/SDC4/PDE4B/TMOD2/MYH6/PALLD/ACTG1/SRI/CASQ1/PDLIM3	45
CC	GO:0016605	PML body	24/2382	99/19717	0.0005834	0.01334	0.01135	ISG20/PPARGC1A/SQSTM1/DAXX/TP53INP2/RPA2/MKNK2/TCF7L2/ARNTL/HIPK2/TP53INP1/NSMCE2/SIRT1/RPAIN/RNF4/EIF3E/TOPORS/SUMO3/KLHL20/SP100/MAX/PATL1/ZNF451/MORC3	24
CC	GO:0001726	ruffle	36/2382	172/19717	0.0006527	0.01446	0.0123	CYTH3/CDK6/FSCN1/ASAP3/PDPN/PSD4/CORO1C/ROCK1/PAK1/LIMA1/WWC1/DDX58/MYADM/MKLN1/RDX/RINL/PODXL/PPP1R9B/FGD4/FGD1/S100A11/PLEKHO1/ARF6/EPS8/GSN/APPL2/DIAPH1/MYO10/PDXP/KSR1/PALLD/FERMT1/MYH9/SH3YL1/TLN1/WASF2	36
CC	GO:0030864	cortical actin cytoskeleton	22/2382	90/19717	0.0008605	0.01849	0.01573	DBN1/SLC2A1/ACTR3/CALD1/MYADM/SHROOM3/RDX/DSTN/PLEKHH2/FLOT1/CAPZA2/SHROOM2/GSN/BIN3/CAP2/KRT19/GYS2/GMFB/ACTR2/MYH9/CAPN2/EPB41L2	22
CC	GO:0090575	RNA polymerase II transcription factor complex	34/2382	163/19717	0.0009659	0.01984	0.01688	CEBPB/TCF12/RXRA/TCF7L2/E2F2/HIPK2/ERCC2/THRA/YAP1/CARM1/ASCL2/ATF1/VDR/JUNB/E2F6/TAF13/CEBPA/MED8/TAF7L/MMS19/GTF2H5/TAF6L/ASCL3/MAX/PPARG/TLE1/MNAT1/TFDP1/STAT3/POU2AF1/GTF2F2/CDK7/TADA3/CBFB	34
CC	GO:0031301	integral component of organelle membrane	42/2382	214/19717	0.0009795	0.01984	0.01688	BID/TPST1/COX11/BET1/SYS1/PISD/VAMP4/STX6/MAN1C1/A4GALT/DMPK/SLC35A1/CPT1A/CSGALNACT1/CSGALNACT2/ABCB10/UBIAD1/POMGNT1/ABCD1/QSOX2/SYT4/P2RX3/PEX11G/SYT1/SGMS2/STX16/PEX11B/IMMT/VAMP7/FAR1/SLC35B4/STEAP2/PEX26/SLC35B1/ATP13A2/APOOL/P2RX7/SAMD8/UNC50/RER1/VAMP5/TIMM17B	42
CC	GO:0030175	filopodium	24/2382	104/19717	0.001228	0.0236	0.02007	VCAM1/TUBB3/FSCN1/PDPN/NGDN/RUFY3/ACTC1/RDX/PODXL/PPP1R9B/FGD4/CDK5/OSBPL3/ENAH/ARF6/TIAM2/HLA-G/CBX6/MYO10/FARP1/TBC1D10C/CDC42/ITGA6/RAPH1	24
CC	GO:0030863	cortical cytoskeleton	26/2382	116/19717	0.001242	0.0236	0.02007	DBN1/SLC2A1/ACTR3/CALD1/MYADM/SHROOM3/RDX/DSTN/PLEKHH2/FLOT1/TPM4/CAPZA2/SHROOM2/GSN/ACTB/BIN3/ACTN4/DLG4/CAP2/KRT19/GYS2/GMFB/ACTR2/MYH9/CAPN2/EPB41L2	26
CC	GO:0055038	recycling endosome membrane	20/2382	81/19717	0.001269	0.0236	0.02007	PDLIM4/EHD4/ZFYVE27/RAB13/HLA-E/HLA-F/HLA-A/MICALL1/RAB11FIP2/RAB4A/EHD1/CLIP3/OPTN/ARF6/SCAMP4/HLA-G/HLA-B/GRIPAP1/FZD7/HLA-H	20
CC	GO:0030017	sarcomere	40/2382	204/19717	0.001298	0.0236	0.02007	AHNAK2/FLNC/PDLIM4/PSMA6/HSPB1/NEXN/SQSTM1/SLC2A1/CORO1C/PAK1/CALM1/PPP1R12A/ANK3/FHL2/ACTC1/CRYAB/MYOM1/KAT2B/FLNB/TPM4/ARF1/MYOM3/TIMP4/PDLIM5/FBXL22/CALM2/ACTN4/FERMT2/FKBP1A/KCTD6/KRT19/PDLIM2/PPP3CA/PDE4B/TMOD2/MYH6/PALLD/SRI/CASQ1/PDLIM3	40
CC	GO:0031674	I band	30/2382	143/19717	0.001693	0.02991	0.02544	AHNAK2/FLNC/PDLIM4/HSPB1/NEXN/SLC2A1/PAK1/PPP1R12A/ANK3/FHL2/ACTC1/CRYAB/MYOM1/KAT2B/FLNB/MYOM3/PDLIM5/FBXL22/ACTN4/FERMT2/FKBP1A/KRT19/PDLIM2/PPP3CA/PDE4B/MYH6/PALLD/SRI/CASQ1/PDLIM3	30
CC	GO:0032154	cleavage furrow	15/2382	55/19717	0.00173	0.02991	0.02544	PLCD3/LIMA1/SSH1/RDX/RHOB/KLHDC8B/ARF6/MYLK/RALA/PDXP/ZFYVE19/PKN2/MYH9/DCTN3/MYH10	15
CC	GO:0031300	intrinsic component of organelle membrane	44/2382	237/19717	0.002377	0.04013	0.03414	BID/TPST1/COX11/BET1/SYS1/PISD/VAMP4/STX6/MAN1C1/A4GALT/DMPK/SLC35A1/CPT1A/CSGALNACT1/RAB4A/CSGALNACT2/ABCB10/UBIAD1/POMGNT1/ABCD1/QSOX2/RAB3A/SYT4/P2RX3/PEX11G/SYT1/SGMS2/STX16/PEX11B/IMMT/VAMP7/FAR1/SLC35B4/STEAP2/PEX26/SLC35B1/ATP13A2/APOOL/P2RX7/SAMD8/UNC50/RER1/VAMP5/TIMM17B	44
CC	GO:0032155	cell division site part	16/2382	63/19717	0.002752	0.04538	0.03861	PLCD3/LIMA1/SSH1/RDX/RHOB/KLHDC8B/ARF6/MYLK/RALA/PDXP/ZFYVE19/PKN2/MYH9/DCTN3/MYH10/TUBGCP4	16
CC	GO:0005923	bicellular tight junction	26/2382	123/19717	0.002976	0.04796	0.0408	CYTH3/CLDN1/MXRA8/RAB13/JAM3/CGNL1/JAM2/DDX58/EPB41L4B/CCND1/ANK3/CLDN12/CLDN14/LIN7A/AMOTL1/SHROOM2/CLDN20/TACSTD2/USP53/CLDN7/MPDZ/TJP1/CLDN17/LIN7C/PDCD6IP/NPHP1	26
CC	GO:0030136	clathrin-coated vesicle	36/2382	188/19717	0.003325	0.05152	0.04383	DAB2/IL7R/EREG/REEP6/EPS15/SORT1/VAMP4/STX6/VWF/WIPI1/SGIP1/EDN1/MYO1E/TGFA/FZD2/HBEGF/SH3BP4/CLTC/MALL/IGF2R/WNT5A/RAB3A/NECAP2/FZD4/SYT1/HLA-DQB1/TMED9/TMED10/VAMP7/STEAP2/M6PR/RASSF9/DVL1/DVL2/PICALM/SNX3	36
CC	GO:1904813	ficolin-1-rich granule lumen	26/2382	124/19717	0.003343	0.05152	0.04383	TNFAIP6/PSMB7/PYGL/CTSS/VCL/FTH1/IDH1/AMPD3/COMMD3/GSDMD/GLB1/CAND1/PPIA/MMP9/IMPDH2/CRISPLD2/ATG7/PAFAH1B2/GSN/ACTR10/GYG1/HBB/ACTR2/CSTB/ALDOC/SERPINA1	26
CC	GO:0044438	microbody part	22/2382	100/19717	0.003612	0.05335	0.04539	ACOX2/IDH1/NUDT7/CROT/AMACR/PXMP4/ABCD1/TMEM135/IMPDH2/FNDC5/ARF1/DECR2/PEX11G/LONP2/PEX1/PEX11B/ACOT8/PECR/SCP2/FAR1/PEX26/ACOXL	22
CC	GO:0044439	peroxisomal part	22/2382	100/19717	0.003612	0.05335	0.04539	ACOX2/IDH1/NUDT7/CROT/AMACR/PXMP4/ABCD1/TMEM135/IMPDH2/FNDC5/ARF1/DECR2/PEX11G/LONP2/PEX1/PEX11B/ACOT8/PECR/SCP2/FAR1/PEX26/ACOXL	22
CC	GO:0030018	Z disc	27/2382	132/19717	0.004051	0.05861	0.04986	AHNAK2/FLNC/PDLIM4/HSPB1/NEXN/SLC2A1/PAK1/PPP1R12A/ANK3/FHL2/CRYAB/MYOM1/FLNB/MYOM3/PDLIM5/FBXL22/ACTN4/FKBP1A/KRT19/PDLIM2/PPP3CA/PDE4B/MYH6/PALLD/SRI/CASQ1/PDLIM3	27
CC	GO:0044448	cell cortex part	35/2382	184/19717	0.004194	0.05947	0.05059	TNFAIP2/DBN1/SLC2A1/ACTR3/CALD1/MYADM/PKD2/SHROOM3/RDX/DSTN/GPSM2/DCTN1/PHLDB1/PLEKHH2/TCHP/FLOT1/TPM4/PHLDB2/CAPZA2/SHROOM2/GSN/ACTB/BIN3/ACTN4/DLG4/STIM1/CAP2/KRT19/GYS2/GMFB/ACTR2/MYH9/PPFIA3/CAPN2/EPB41L2	35
CC	GO:1904724	tertiary granule lumen	14/2382	55/19717	0.004829	0.06713	0.05711	CXCL1/TNFAIP6/CNN2/CTSS/FTH1/IDH1/GSDMD/METTL7A/PRG3/MMP9/PTX3/HBB/CSTB/ALDOC	14
CC	GO:0043034	costamere	7/2382	19/19717	0.005007	0.06774	0.05763	AHNAK2/FLNC/VCL/ANK3/SYNM/KRT19/SDC4	7
CC	GO:0070160	tight junction	26/2382	128/19717	0.00521	0.06774	0.05763	CYTH3/CLDN1/MXRA8/RAB13/JAM3/CGNL1/JAM2/DDX58/EPB41L4B/CCND1/ANK3/CLDN12/CLDN14/LIN7A/AMOTL1/SHROOM2/CLDN20/TACSTD2/USP53/CLDN7/MPDZ/TJP1/CLDN17/LIN7C/PDCD6IP/NPHP1	26
CC	GO:0031091	platelet alpha granule	20/2382	91/19717	0.005428	0.06774	0.05763	THBS2/VEGFA/VWF/THBS1/LHFPL2/TGFB2/PHACTR2/SRGN/SYTL4/SPARC/ACTN4/STXBP1/SERPINE1/GAS6/VAMP7/SERPINA3/IGF1/APOOL/SERPINA1/SERPINF2	20
CC	GO:0000151	ubiquitin ligase complex	49/2382	282/19717	0.005517	0.06774	0.05763	ZSWIM4/UBE2L6/FBXL2/LMO7/KLHL3/RNF20/UBE4A/MED10/ANKIB1/CDC16/DDA1/MKLN1/ENC1/RNF14/DYRK2/FBXL6/NCCRP1/ARIH2/CAND1/DDB2/UBR1/ASB1/ARIH1/DCAF16/SPSB1/TRAF2/ANAPC13/TRIM21/RNF144B/CRBN/UBE2E1/DCUN1D4/FBXW4/TOPORS/KLHL20/DET1/KLHL13/FBXO17/RBCK1/ASB2/MED20/DCAF12L2/FBXL5/CDC23/UBE4B/PHC3/NEDD4/PHC2/UBE2S	49
CC	GO:0071556	integral component of lumenal side of endoplasmic reticulum membrane	9/2382	29/19717	0.005634	0.06774	0.05763	HLA-E/HLA-F/PKD2/HLA-A/HLA-G/HLA-DQB1/TAPBP/HLA-B/HLA-H	9
CC	GO:0098553	lumenal side of endoplasmic reticulum membrane	9/2382	29/19717	0.005634	0.06774	0.05763	HLA-E/HLA-F/PKD2/HLA-A/HLA-G/HLA-DQB1/TAPBP/HLA-B/HLA-H	9
CC	GO:0031253	cell projection membrane	58/2382	345/19717	0.005641	0.06774	0.05763	GPR37L1/SLC11A2/ADORA2A/FSCN1/ATP8B1/PDPN/PSD4/GABARAPL1/SLC7A11/CORO1C/MXRA8/PAK1/LIMA1/WWC1/CD44/EPS15/DDX58/PKD2/DHRS3/PODXL/EPB41L3/PPP1R9B/NPC1L1/GNA13/BBS2/GNA12/EHD1/PLEKHO1/ARPC2/ABCC2/ADORA1/KCNB1/ARF6/EPS8/APPL2/GPR161/CYBRD1/FERMT2/PLEK2/PLXND1/ASAP1/DIAPH1/HLA-G/GABRA3/SCNN1A/MYO10/PDXP/SLC26A3/KSR1/TBC1D10C/VEZT/FERMT1/PCDHB13/SH3YL1/SHOC2/LRRC30/MYO1D/TLN1	58
CC	GO:0044798	nuclear transcription factor complex	37/2382	201/19717	0.005783	0.06774	0.05763	CEBPB/TCF12/RXRA/KLF4/TCF7L2/E2F2/HIPK2/ERCC2/THRA/YAP1/CARM1/ASCL2/ATF1/VDR/JUNB/E2F6/TAF13/SOX7/CEBPA/MED8/TAF7L/MMS19/GTF2H5/TAF6L/ASCL3/MAX/PPARG/TLE1/MNAT1/TFDP1/GTF3C4/STAT3/POU2AF1/GTF2F2/CDK7/TADA3/CBFB	37
CC	GO:0008287	protein serine/threonine phosphatase complex	12/2382	45/19717	0.005897	0.06774	0.05763	PPP3CC/PPP4R4/PPP1R15A/PPP2R1B/PPP1R12A/PPP1R9B/PPP4C/TOX4/PPP2R5E/PPP3CA/PPP2R5C/SHOC2	12
CC	GO:1903293	phosphatase complex	12/2382	45/19717	0.005897	0.06774	0.05763	PPP3CC/PPP4R4/PPP1R15A/PPP2R1B/PPP1R12A/PPP1R9B/PPP4C/TOX4/PPP2R5E/PPP3CA/PPP2R5C/SHOC2	12
CC	GO:0098858	actin-based cell projection	38/2382	208/19717	0.005924	0.06774	0.05763	AKR1B1/VCAM1/TUBB3/FSCN1/ATP8B1/PDPN/CD44/NGDN/RUFY3/FMN2/OXTR/ACTC1/RDX/PODXL/PPP1R9B/FGD4/BBS2/CDK5/OSBPL3/ENAH/ARF6/EPS8/TIAM2/DOCK4/HLA-G/KPTN/CBX6/MYO10/PCDH15/FARP1/TBC1D10C/CDC42/VEZT/ITGA6/CLCA1/RAPH1/ATP6V1E1/HOMER2	38
CC	GO:0042383	sarcolemma	27/2382	136/19717	0.006162	0.06835	0.05814	VCAM1/AHNAK2/FLNC/SLC2A1/CORO1C/SLC38A2/POPDC2/VCL/CAMK2D/ANK3/RDX/SGCD/SYNM/FLOT1/STAC/KCNB1/COL6A3/SLC30A1/SGCG/KRT19/PPP3CA/SNTA1/KCND3/SNTB1/SRI/CASQ1/SGCB	27
CC	GO:0032153	cell division site	16/2382	68/19717	0.00617	0.06835	0.05814	PLCD3/LIMA1/SSH1/RDX/RHOB/KLHDC8B/ARF6/MYLK/RALA/PDXP/ZFYVE19/PKN2/MYH9/DCTN3/MYH10/TUBGCP4	16
CC	GO:0016528	sarcoplasm	18/2382	80/19717	0.006277	0.06847	0.05825	FLNC/HK2/FABP3/CAMK2D/RASD1/ANK3/THBS1/DMPK/SGCD/ITPR2/MEF2C/GSN/CAMK2G/ATP2A2/STIM1/FKBP1A/SRI/CASQ1	18
CC	GO:0045178	basal part of cell	13/2382	51/19717	0.006412	0.06886	0.05858	SLC11A2/ITGA1/KRT14/EPS15/BMPR2/PKD2/ANK3/EDN1/PHLDB1/ITGA2/PHLDB2/TACSTD2/ITGA6	13
CC	GO:0043296	apical junction complex	28/2382	143/19717	0.006508	0.06886	0.05858	CYTH3/CLDN1/MXRA8/RAB13/JAM3/CGNL1/JAM2/DDX58/EPB41L4B/CCND1/ANK3/SHROOM3/CLDN12/CLDN14/LIN7A/AMOTL1/SHROOM2/CLDN20/TACSTD2/USP53/CLDN7/MPDZ/PKN2/TJP1/CLDN17/LIN7C/PDCD6IP/NPHP1	28
CC	GO:0016328	lateral plasma membrane	14/2382	57/19717	0.006778	0.07067	0.06012	CLDN1/CORO1C/RAB13/NKD2/ANK3/CLDN12/GPSM2/GJB2/GNA12/KCNB1/TACSTD2/SNTA1/DVL1/DVL2	14
CC	GO:0005769	early endosome	58/2382	350/19717	0.007634	0.07844	0.06673	VCAM1/SLC11A2/PDLIM4/EHD4/SAMD9L/RIN3/TOM1/HLA-E/HLA-F/RAB38/EPS15/SORT1/BACE1/STX6/SNX4/ITCH/HLA-A/NIPA1/F2R/LIPG/RHOB/NISCH/RAB4A/IGF2R/FLOT1/EHD1/CLIP3/ARRDC4/ARRDC3/VPS35/RAB32/ARF6/WDFY1/HAVCR2/APPL2/CCDC93/PLEKHF2/TLR3/INPP5B/HLA-G/WDR91/HSD17B6/STEAP2/MYO1D/TMEM108/RAB31/HLA-B/GRIPAP1/HLA-H/ANKRD27/DNER/VPS26A/MAGEL2/SGK3/PICALM/TMEM165/WASF2/SNX3	58
CC	GO:0060205	cytoplasmic vesicle lumen	56/2382	338/19717	0.008668	0.0878	0.07469	CXCL1/NFKB1/PSMB7/PYGL/C3/VEGFA/GIP/ROCK1/CNN2/VCL/BACE1/VWF/IDH1/AMPD3/THBS1/ADA/GLA/GSDMD/GLB1/SDCBP/TGFB2/PRG3/CAND1/DNAJC3/PPIA/S100A11/CEP290/IMPDH2/CRISPLD2/SRGN/ATG7/PAFAH1B2/GSN/ACTR10/HYOU1/SPARC/ACTN4/SERPINB1/GYG1/FRK/PTX3/PRKCD/AGA/SERPINE1/HBB/GAS6/ACTR2/SERPINA4/SERPINA3/GCA/CSTB/IGF1/ALDOC/APOOL/SERPINA1/SERPINF2	56
CC	GO:0008305	integrin complex	9/2382	31/19717	0.00908	0.09054	0.07702	ITGA1/ITGB5/ITGA4/ITGB8/ITGA2/ITGA11/ITGAE/ITGA6/ITGBL1	9
CC	GO:0031983	vesicle lumen	56/2382	339/19717	0.009195	0.09054	0.07702	CXCL1/NFKB1/PSMB7/PYGL/C3/VEGFA/GIP/ROCK1/CNN2/VCL/BACE1/VWF/IDH1/AMPD3/THBS1/ADA/GLA/GSDMD/GLB1/SDCBP/TGFB2/PRG3/CAND1/DNAJC3/PPIA/S100A11/CEP290/IMPDH2/CRISPLD2/SRGN/ATG7/PAFAH1B2/GSN/ACTR10/HYOU1/SPARC/ACTN4/SERPINB1/GYG1/FRK/PTX3/PRKCD/AGA/SERPINE1/HBB/GAS6/ACTR2/SERPINA4/SERPINA3/GCA/CSTB/IGF1/ALDOC/APOOL/SERPINA1/SERPINF2	56
CC	GO:0071564	npBAF complex	5/2382	12/19717	0.00975	0.09469	0.08056	SMARCD3/SMARCA2/ARID1A/SMARCE1/PHF10	5
CC	GO:0000932	P-body	18/2382	84/19717	0.01054	0.101	0.08589	ZC3H12A/PSMA6/SQSTM1/CAPRIN1/APOBEC3G/MOV10/ZFP36/WTIP/BTBD2/APOBEC3H/DCP1A/TRIM21/SAMD4B/CNOT8/APOBEC3F/LSM6/PATL1/MEX3B	18
CC	GO:0005913	cell-cell adherens junction	23/2382	117/19717	0.01221	0.1154	0.0982	PDLIM4/VEGFA/VCL/CDC42EP1/BMPR2/TRIM29/OXTR/RDX/FLOT1/S100A11/CNN3/SHROOM2/PDLIM5/ATP2A2/PTPRM/PKP4/PDLIM2/ZYX/TJP1/MYH9/CDH4/ITGA6/PDLIM3	23
CC	GO:0098862	cluster of actin-based cell projections	28/2382	150/19717	0.01242	0.1159	0.09856	SLC11A2/ATP8B1/IDO1/SLC7A11/SLC38A2/LIMA1/ACTR3/MYO1E/RDX/NPC1L1/GNA13/BBS2/FLNB/GNA12/ABCC2/CAPZA2/EPS8/CYBRD1/ACTN4/DOCK4/KPTN/SLC26A3/PCDH15/VEZT/MYH9/MYH10/MYO1D/HOMER2	28
CC	GO:0098562	cytoplasmic side of membrane	32/2382	178/19717	0.01363	0.1251	0.1064	CYTH3/KIT/BIRC2/DNAJA1/ESYT1/TRAF3/FYN/CHMP4B/PKD2/CYLD/GNG11/THADA/RGS2/ERRFI1/GNA13/GNA12/GEM/STAC/TRAF2/ATP2A2/FERMT2/DLG4/CNR2/FKBP1A/FRK/PKP4/PPP3CA/CBX6/FARP1/PLEKHA4/GNG2/GRAMD1A	32
CC	GO:0101002	ficolin-1-rich granule	33/2382	185/19717	0.01385	0.1251	0.1064	TNFAIP6/PSMB7/PYGL/CTSS/VCL/CD58/FTH1/IDH1/AMPD3/COMMD3/GSDMD/GLB1/SIRPA/CAND1/PPIA/MMP9/IMPDH2/CRISPLD2/ATG7/PAFAH1B2/GSN/DYNLL1/ACTR10/GYG1/DIAPH1/HBB/ACTR2/TBC1D10C/CSTB/ALDOC/SERPINA1/UBR4/ADAM8	33
CC	GO:0005903	brush border	20/2382	99/19717	0.01394	0.1251	0.1064	SLC11A2/ATP8B1/SLC7A11/SLC38A2/LIMA1/ACTR3/MYO1E/NPC1L1/GNA13/FLNB/GNA12/ABCC2/CAPZA2/EPS8/CYBRD1/ACTN4/SLC26A3/MYH9/MYH10/MYO1D	20
CC	GO:0005675	transcription factor TFIIH holo complex	5/2382	13/19717	0.01429	0.1251	0.1064	ERCC2/MMS19/GTF2H5/MNAT1/CDK7	5
CC	GO:0099243	extrinsic component of synaptic membrane	5/2382	13/19717	0.01429	0.1251	0.1064	DGKI/STXBP5/KPNA2/CRKL/PICALM	5
CC	GO:0005811	lipid droplet	17/2382	81/19717	0.01553	0.1339	0.1139	RSAD2/G0S2/PLA2G4A/PLIN2/SET/RDH10/DHRS3/RAB3GAP1/METTL7A/AQP7/STARD13/EHD1/TMEM135/HSD3B7/ABHD5/SIGMAR1/FAAH2	17
CC	GO:0030496	midbody	31/2382	173/19717	0.01567	0.1339	0.1139	CHMP1B/SLC2A1/ANXA11/LZTS2/CHMP4B/SSH1/CYLD/RDX/KLHDC8B/BCL3/GEM/ARF6/MICAL3/TOPORS/BIRC6/PKP4/GDI1/KLHL13/ZNF330/CRMP1/MARK4/RALA/PDXP/MITD1/ZFYVE19/PKN2/CDC42/DCTN3/MYH10/ARL2BP/PDCD6IP	31
CC	GO:0034774	secretory granule lumen	52/2382	321/19717	0.01672	0.1411	0.12	CXCL1/NFKB1/PSMB7/PYGL/C3/VEGFA/GIP/ROCK1/CNN2/VCL/VWF/IDH1/AMPD3/THBS1/GLA/GSDMD/GLB1/SDCBP/TGFB2/PRG3/CAND1/DNAJC3/PPIA/S100A11/CEP290/IMPDH2/CRISPLD2/SRGN/ATG7/PAFAH1B2/GSN/ACTR10/SPARC/ACTN4/SERPINB1/GYG1/FRK/PTX3/PRKCD/AGA/SERPINE1/GAS6/ACTR2/SERPINA4/SERPINA3/GCA/CSTB/IGF1/ALDOC/APOOL/SERPINA1/SERPINF2	52
CC	GO:0098636	protein complex involved in cell adhesion	9/2382	34/19717	0.01695	0.1413	0.1202	ITGA1/ITGB5/ITGA4/ITGB8/ITGA2/ITGA11/ITGAE/ITGA6/ITGBL1	9
CC	GO:0009898	cytoplasmic side of plasma membrane	28/2382	154/19717	0.01739	0.1413	0.1202	CYTH3/KIT/BIRC2/ESYT1/TRAF3/FYN/CHMP4B/CYLD/GNG11/RGS2/ERRFI1/GNA13/GNA12/GEM/STAC/TRAF2/ATP2A2/FERMT2/DLG4/CNR2/FRK/PKP4/PPP3CA/CBX6/FARP1/PLEKHA4/GNG2/GRAMD1A	28
CC	GO:0005777	peroxisome	25/2382	134/19717	0.01754	0.1413	0.1202	ACOX2/TRIM37/IDH1/NUDT7/CROT/AMACR/PXMP4/ABCD1/TMEM135/IMPDH2/FNDC5/ARF1/DECR2/PEX11G/LONP2/PEX1/PEX11B/ACOT8/PECR/SCP2/IDI1/FAR1/PEX26/ACOXL/HSDL2	25
CC	GO:0042579	microbody	25/2382	134/19717	0.01754	0.1413	0.1202	ACOX2/TRIM37/IDH1/NUDT7/CROT/AMACR/PXMP4/ABCD1/TMEM135/IMPDH2/FNDC5/ARF1/DECR2/PEX11G/LONP2/PEX1/PEX11B/ACOT8/PECR/SCP2/IDI1/FAR1/PEX26/ACOXL/HSDL2	25
CC	GO:0043025	neuronal cell body	76/2382	497/19717	0.01783	0.142	0.1208	ITGA1/KCNN4/ADORA2A/PPARGC1A/GDPD5/PDE1C/TNFRSF1B/IL6ST/GIP/SLC38A2/ELOVL5/ENO2/SORT1/BMPR2/PDE1A/BACE1/RUFY3/ITGA4/CYBA/ADA/AKAP12/SRD5A1/CRYAB/PPT1/MBP/GJC2/DCTN1/TGFB2/MAP1A/LPAR1/CYGB/FLNB/CNN3/CDK5/ADORA1/KCNB1/SNAP47/VPS35/KCND1/SYT4/DGKI/P2RX3/UBXN1/BGLAP/CACNA1F/CACNA1B/ASS1/STAU1/SNPH/CNR2/IAPP/GDI1/NGB/RTN4/GLRX2/GRIN3A/ABL1/CBX6/MYO10/FXR2/UBB/KCND3/RIN1/CDC42/ATP13A2/SEMA4F/ROGDI/MYH10/MYO1D/DVL1/P2RX7/KCNB2/HOMER2/DNER/CAPN2/PICALM	76
CC	GO:0030665	clathrin-coated vesicle membrane	22/2382	115/19717	0.01893	0.1481	0.126	DAB2/IL7R/EREG/REEP6/EPS15/VAMP4/SGIP1/TGFA/FZD2/HBEGF/CLTC/IGF2R/WNT5A/RAB3A/NECAP2/FZD4/SYT1/HLA-DQB1/VAMP7/M6PR/RASSF9/PICALM	22
CC	GO:0005788	endoplasmic reticulum lumen	50/2382	309/19717	0.01901	0.1481	0.126	PTGS2/IL6/CSF1/TMEM132A/C3/MXRA8/GIP/BMP4/LAMB1/IL12A/AFP/COL1A1/DNAJB9/VCAN/BACE1/THBS1/DBI/P4HA2/EDN1/KTN1/COL5A2/PDGFD/SDC2/DNAJC3/EBI3/WNT5B/WNT5A/RCN3/COL6A3/ARSK/TNC/ESD/FBN1/BGLAP/HYOU1/SERPINH1/TOR3A/PDGFC/COL16A1/COL4A1/COL24A1/COL1A2/GAS6/TOR1A/PRSS23/ADAMTSL1/SERPINA1/COL5A1/CASQ1/TXNDC16	50
CC	GO:0005744	TIM23 mitochondrial import inner membrane translocase complex	5/2382	14/19717	0.02005	0.1545	0.1315	DNAJC19/DNAJC15/GRPEL1/GRPEL2/TIMM17B	5
CC	GO:0030135	coated vesicle	47/2382	289/19717	0.02063	0.1552	0.132	DAB2/IL7R/EREG/HLA-E/REEP6/HLA-F/EPS15/SORT1/VAMP4/STX6/VWF/WIPI1/SGIP1/HLA-A/CCDC88A/EDN1/MYO1E/TGFA/FZD2/HBEGF/SH3BP4/CLTC/YIPF6/MALL/IGF2R/WNT5A/RAB3A/ARF1/NECAP2/FZD4/HLA-G/SYT1/HLA-DQB1/TMED9/TMED10/VAMP7/STEAP2/M6PR/RASSF9/CNIH2/DVL1/DVL2/SERPINA1/HLA-B/HLA-H/PICALM/SNX3	47
CC	GO:0016010	dystrophin-associated glycoprotein complex	6/2382	19/19717	0.02079	0.1552	0.132	SGCD/SGCG/KRT19/SNTA1/SNTB1/SGCB	6
CC	GO:0090665	glycoprotein complex	6/2382	19/19717	0.02079	0.1552	0.132	SGCD/SGCG/KRT19/SNTA1/SNTB1/SGCB	6
CC	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	18/2382	91/19717	0.02322	0.1715	0.1459	CYTH3/ESYT1/FYN/CYLD/GNG11/ERRFI1/GNA13/GNA12/STAC/ATP2A2/FERMT2/DLG4/CNR2/FRK/FARP1/PLEKHA4/GNG2/GRAMD1A	18
CC	GO:0005778	peroxisomal membrane	13/2382	60/19717	0.02495	0.1791	0.1524	PXMP4/ABCD1/TMEM135/IMPDH2/FNDC5/ARF1/DECR2/PEX11G/PEX1/PEX11B/PECR/FAR1/PEX26	13
CC	GO:0031903	microbody membrane	13/2382	60/19717	0.02495	0.1791	0.1524	PXMP4/ABCD1/TMEM135/IMPDH2/FNDC5/ARF1/DECR2/PEX11G/PEX1/PEX11B/PECR/FAR1/PEX26	13
CC	GO:0042611	MHC protein complex	7/2382	25/19717	0.02501	0.1791	0.1524	HLA-E/HLA-F/HLA-A/HLA-G/HLA-DQB1/HLA-B/HLA-H	7
CC	GO:0001650	fibrillar center	24/2382	132/19717	0.02617	0.1851	0.1575	DAB2/NFKBIE/RSAD2/SESN1/LIPA/JAZF1/SMARCA5/ACACA/CDCA7L/NUAK1/TMEM217/RPAIN/FAM111A/INO80C/FOXJ2/PAFAH1B2/ICK/UBD/EN2/DDX46/BTBD10/URB1/AKNA/NFIB	24
CC	GO:0030904	retromer complex	6/2382	20/19717	0.02674	0.1851	0.1575	DENND5A/DCTN1/VPS35/VPS26A/MAGEL2/SNX3	6
CC	GO:0071782	endoplasmic reticulum tubular network	6/2382	20/19717	0.02674	0.1851	0.1575	ZFYVE27/RAB3GAP1/RAB18/ATL1/STIM1/RTN4	6
CC	GO:0005779	integral component of peroxisomal membrane	5/2382	15/19717	0.02715	0.1851	0.1575	ABCD1/PEX11G/PEX11B/FAR1/PEX26	5
CC	GO:0031231	intrinsic component of peroxisomal membrane	5/2382	15/19717	0.02715	0.1851	0.1575	ABCD1/PEX11G/PEX11B/FAR1/PEX26	5
CC	GO:0031093	platelet alpha granule lumen	14/2382	67/19717	0.02745	0.1854	0.1577	VEGFA/VWF/THBS1/TGFB2/SRGN/SPARC/ACTN4/SERPINE1/GAS6/SERPINA3/IGF1/APOOL/SERPINA1/SERPINF2	14
CC	GO:0019898	extrinsic component of membrane	47/2382	295/19717	0.02864	0.1916	0.163	ZC3H12A/CYTH3/PIK3CD/ESYT1/SOCS1/SOCS3/FYN/WIPI1/PIK3R2/CYLD/MICALL1/GNG11/DMBT1/PIK3R3/ERRFI1/GNA13/GNA12/STAC/COQ3/MMP27/DGKI/SYTL4/RPH3A/ATP2A2/FERMT2/DLG4/STXBP5/CNR2/FKBP1A/FRK/SOCS2/WDR91/WDR45/MITD1/TOR1A/KPNA2/FARP1/CDH4/OSR1/GRIPAP1/PLEKHA4/NMT2/CRKL/PICALM/GNG2/GRAMD1A/SNX10	47
CC	GO:0030133	transport vesicle	60/2382	392/19717	0.03166	0.209	0.1778	IL33/RAB9A/NKD2/HLA-E/BET1/HLA-F/SORT1/VAMP4/STX3/BACE1/STX6/HLA-A/CCDC88A/WDR7/EDN1/FGFRL1/TGFA/PPT1/DPYSL3/CLTC/RAB4A/SYPL2/APH1B/IGF2R/CRISPLD2/SNAP47/RAB3A/COPS4/BCL2L1/SYT4/DGKI/SYTL4/RPH3A/DLG4/STXBP5/PLEKHF2/HLA-G/SYT1/HLA-DQB1/STX16/TMED9/PDE4B/VDAC1/TOR1A/TRAPPC4/TMED10/AP3S1/VAMP7/STEAP2/M6PR/RASSF9/CNIH2/ATP13A2/ROGDI/IGF1/HLA-B/HLA-H/ANKRD27/PICALM/VPS45	60
CC	GO:0055037	recycling endosome	30/2382	176/19717	0.03217	0.209	0.1778	SLC11A2/PDLIM4/EHD4/ZFYVE27/RAB13/HLA-E/HLA-F/BACE1/HLA-A/MICALL1/RAB11FIP2/NISCH/RAB4A/EHD1/CLIP3/OPTN/ARF6/TNF/GPR161/SCAMP4/HLA-G/RAB11FIP1/RASSF9/HLA-B/GRIPAP1/FZD7/HLA-H/SLC9A9/SGK3/TUBGCP4	30
CC	GO:0031941	filamentous actin	8/2382	32/19717	0.03297	0.209	0.1778	PDLIM4/PKD2/DPYSL3/PDLIM5/PDLIM2/KPTN/ACTG1/PDLIM3	8
CC	GO:1902554	serine/threonine protein kinase complex	17/2382	88/19717	0.03307	0.209	0.1778	ERN1/CDK6/CCND1/CCNO/ERCC2/PHKB/CCNG2/CDK5/SESN2/CCNG1/MMS19/GTF2H5/CCNJL/CDKN1A/PHKA2/MNAT1/CDK7	17
CC	GO:0005583	fibrillar collagen trimer	4/2382	11/19717	0.03482	0.209	0.1778	COL1A1/COL5A2/COL1A2/COL5A1	4
CC	GO:0005885	Arp2/3 protein complex	4/2382	11/19717	0.03482	0.209	0.1778	ARPC1A/ACTR3/ARPC2/ACTR2	4
CC	GO:0031094	platelet dense tubular network	4/2382	11/19717	0.03482	0.209	0.1778	F2R/EHD1/ITPR2/ATP2A2	4
CC	GO:0031932	TORC2 complex	4/2382	11/19717	0.03482	0.209	0.1778	SESN1/SESN3/SESN2/PRR5	4
CC	GO:0035631	CD40 receptor complex	4/2382	11/19717	0.03482	0.209	0.1778	BIRC2/TRAF3/CD40/TRAF2	4
CC	GO:0042589	zymogen granule membrane	4/2382	11/19717	0.03482	0.209	0.1778	STX3/DMBT1/TMED10/CLCA1	4
CC	GO:0098643	banded collagen fibril	4/2382	11/19717	0.03482	0.209	0.1778	COL1A1/COL5A2/COL1A2/COL5A1	4
CC	GO:0005759	mitochondrial matrix	70/2382	469/19717	0.03558	0.209	0.1778	SOD2/MRPS24/GLS/MTHFD2L/DNAJC19/PPIF/HIBCH/BCKDHB/NARS2/MRPS35/FASTKD5/GFM1/ACAT1/GLUD1/HADH/MTHFD2/ACSF2/MRPS9/MIPEP/MPV17L2/NUDT1/CBR4/FH/PDE12/AADAT/DNAJC15/PDSS2/NDUFAB1/HAGH/REXO2/HIBADH/COQ3/BCL2L1/AMT/ALDH7A1/ADPRHL2/MRPS18C/ACAA2/ABAT/NSUN3/MRPL24/TOP1MT/NUBPL/PDHB/ALAS1/GRPEL1/GRPEL2/ALDH5A1/CPS1/GLRX2/PDK3/VDAC1/POLDIP2/GRSF1/SUCLA2/TK2/MRPL14/ALDH1L2/MRPL3/POLG2/MRPL13/MRPL17/ARL2BP/BCAT2/MRPL48/ACADM/CASQ1/MARS2/SDHAF2/CA5B	70
CC	GO:0030479	actin cortical patch	5/2382	16/19717	0.03566	0.209	0.1778	ACTR3/CAPZA2/BIN3/GMFB/ACTR2	5
CC	GO:0061645	endocytic patch	5/2382	16/19717	0.03566	0.209	0.1778	ACTR3/CAPZA2/BIN3/GMFB/ACTR2	5
CC	GO:0071437	invadopodium	5/2382	16/19717	0.03566	0.209	0.1778	FSCN1/PDPN/PAK1/RUFY3/ACTR2	5
CC	GO:0005770	late endosome	41/2382	256/19717	0.03605	0.2095	0.1782	SLC11A2/PLD1/CHMP1B/SQSTM1/IFNAR1/OSBPL1A/RAB9A/CTSS/IL12A/CHMP4B/BACE1/ANKRD13A/ANXA8/KIDINS220/MICALL1/VPS37D/VPS36/F2R/RHOB/VPS37C/STOML1/ABCA5/IGF2R/VPS35/ARF1/TMEM9/CD79A/ZP2/TMEM106B/WDR91/STARD3NL/MITD1/MCOLN1/VAMP7/NDFIP2/M6PR/ATP13A2/ANKRD27/SLC9A9/TMEM165/VAMP5	41
CC	GO:1902911	protein kinase complex	20/2382	109/19717	0.03648	0.2103	0.1789	ERN1/CDK6/IRS1/CCND1/CCNO/ERCC2/PHKB/CCNG2/CDK5/SESN2/CCNG1/PRKAB2/MMS19/GTF2H5/CCNJL/CDKN1A/PHKA2/MNAT1/SIK1/CDK7	20
CC	GO:0045121	membrane raft	49/2382	315/19717	0.03776	0.2159	0.1837	BIRC3/ICAM1/PTGS2/OLR1/ITGA1/ABCA1/BIRC2/PDPN/PLSCR1/TNFRSF1B/SLC2A1/CORO1C/MYOF/CFLAR/PPP2R1B/FYN/IRS1/BMPR2/FAS/MYADM/BACE1/FADD/PPT1/PODXL/SDCBP/F2R/STOML1/HAS2/MALL/STAT6/FLOT1/EFNB1/CLIP3/TRAF2/SULF1/ARID3A/P2RX3/TNF/LDHB/SERPINH1/STIM1/CD79A/SDC4/BCL10/VDAC1/ORAI1/CBLB/MYO1D/CAPN2	49
CC	GO:0005802	trans-Golgi network	38/2382	236/19717	0.03935	0.2212	0.1882	BACE2/DENND5A/RAB9A/RAB13/COG2/SYS1/RAB38/VAMP4/BACE1/STX6/CHST7/WIPI1/GCC2/CLTC/YIPF6/RHOBTB3/IGF2R/CLIP3/OPTN/RAB32/MYO18A/ARF1/PREPL/GCNT1/KLHL20/SCAMP4/BIRC6/HLA-DQB1/STX16/MMP24/VAMP7/M6PR/TAS2R16/PI4K2B/TRAPPC9/RAB31/COG5/TMEM165	38
CC	GO:0033017	sarcoplasmic reticulum membrane	9/2382	39/19717	0.03957	0.2212	0.1882	CAMK2D/DMPK/ITPR2/CAMK2G/ATP2A2/STIM1/FKBP1A/SRI/CASQ1	9
CC	GO:0098857	membrane microdomain	49/2382	316/19717	0.03962	0.2212	0.1882	BIRC3/ICAM1/PTGS2/OLR1/ITGA1/ABCA1/BIRC2/PDPN/PLSCR1/TNFRSF1B/SLC2A1/CORO1C/MYOF/CFLAR/PPP2R1B/FYN/IRS1/BMPR2/FAS/MYADM/BACE1/FADD/PPT1/PODXL/SDCBP/F2R/STOML1/HAS2/MALL/STAT6/FLOT1/EFNB1/CLIP3/TRAF2/SULF1/ARID3A/P2RX3/TNF/LDHB/SERPINH1/STIM1/CD79A/SDC4/BCL10/VDAC1/ORAI1/CBLB/MYO1D/CAPN2	49
CC	GO:0031258	lamellipodium membrane	6/2382	22/19717	0.04177	0.2296	0.1953	PDPN/CD44/FERMT2/PLEK2/PLXND1/PDXP	6
CC	GO:0097038	perinuclear endoplasmic reticulum	6/2382	22/19717	0.04177	0.2296	0.1953	GDPD5/FYN/CYBA/OSBPL3/CAPN2/OSBPL7	6
CC	GO:0035770	ribonucleoprotein granule	36/2382	223/19717	0.0425	0.2304	0.196	NFKBIZ/ZC3H12A/PSMA6/MBNL1/SQSTM1/EIF4A2/CAPRIN1/ROCK1/SOCS1/APOBEC3G/MOV10/FASTKD5/ZFP36/WTIP/BTBD2/APOBEC3H/ARNTL/GHR/DCP1A/HELZ/PABPC1/TRIM21/SHB/SAMD4B/ACTB/CNOT8/STAU1/APOBEC3F/ROCK2/FXR2/LSM6/GRSF1/PATL1/MEX3B/CDC42/DDX19A	36
CC	GO:0016529	sarcoplasmic reticulum	14/2382	71/19717	0.0429	0.2304	0.196	HK2/CAMK2D/RASD1/ANK3/THBS1/DMPK/SGCD/ITPR2/CAMK2G/ATP2A2/STIM1/FKBP1A/SRI/CASQ1	14
CC	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane	14/2382	71/19717	0.0429	0.2304	0.196	TAP1/TAP2/BET1/TGFA/ROBO1/CLN8/MPPE1/TMED9/TMED10/TAPBP/ERGIC1/CNIH2/PRRG4/SERPINA1	14
CC	GO:1990909	Wnt signalosome	4/2382	12/19717	0.04736	0.251	0.2135	RECK/FZD1/LRP5/DVL1	4
CC	GO:0030662	coated vesicle membrane	30/2382	182/19717	0.04744	0.251	0.2135	DAB2/IL7R/EREG/HLA-E/REEP6/HLA-F/EPS15/VAMP4/SGIP1/HLA-A/TGFA/FZD2/HBEGF/CLTC/IGF2R/WNT5A/RAB3A/NECAP2/FZD4/HLA-G/SYT1/HLA-DQB1/TMED10/VAMP7/M6PR/RASSF9/CNIH2/HLA-B/HLA-H/PICALM	30
CC	GO:0032588	trans-Golgi network membrane	17/2382	92/19717	0.04804	0.2523	0.2147	RAB9A/COG2/SYS1/VAMP4/STX6/CLTC/RHOBTB3/IGF2R/CLIP3/SCAMP4/HLA-DQB1/STX16/MMP24/M6PR/RAB31/COG5/TMEM165	17
CC	GO:0098589	membrane region	50/2382	328/19717	0.04914	0.2562	0.2179	BIRC3/ICAM1/PTGS2/OLR1/ITGA1/ABCA1/BIRC2/PDPN/PLSCR1/TNFRSF1B/SLC2A1/CORO1C/MYOF/CFLAR/PPP2R1B/FYN/IRS1/BMPR2/FAS/MYADM/BACE1/FADD/PPT1/PODXL/SDCBP/F2R/STOML1/HAS2/MALL/STAT6/FLOT1/EFNB1/CLIP3/TRAF2/SULF1/ARID3A/P2RX3/TNF/LDHB/SERPINH1/STIM1/CD79A/SDC4/BCL10/VDAC1/ORAI1/CBLB/MYO1D/BICD2/CAPN2	50
CC	GO:0031201	SNARE complex	10/2382	47/19717	0.05118	0.2633	0.224	BET1/STX3/STX6/SNX4/SNAP47/STXBP5/STX16/VAMP7/TSNARE1/NAPB	10
CC	GO:0036464	cytoplasmic ribonucleoprotein granule	34/2382	212/19717	0.05141	0.2633	0.224	NFKBIZ/ZC3H12A/PSMA6/MBNL1/SQSTM1/EIF4A2/CAPRIN1/ROCK1/SOCS1/APOBEC3G/MOV10/ZFP36/WTIP/BTBD2/APOBEC3H/ARNTL/GHR/DCP1A/HELZ/PABPC1/TRIM21/SHB/SAMD4B/ACTB/CNOT8/STAU1/APOBEC3F/ROCK2/FXR2/LSM6/PATL1/MEX3B/CDC42/DDX19A	34
CC	GO:0031902	late endosome membrane	23/2382	134/19717	0.05163	0.2633	0.224	SLC11A2/PLD1/CHMP1B/CHMP4B/ANXA8/MICALL1/VPS37D/VPS36/RHOB/VPS37C/STOML1/ABCA5/TMEM9/TMEM106B/WDR91/STARD3NL/MITD1/MCOLN1/VAMP7/NDFIP2/ATP13A2/SLC9A9/TMEM165	23
CC	GO:0031256	leading edge membrane	28/2382	170/19717	0.0544	0.2755	0.2344	ADORA2A/PDPN/PSD4/GABARAPL1/CORO1C/PAK1/WWC1/CD44/DDX58/EPB41L3/PPP1R9B/PLEKHO1/ADORA1/KCNB1/EPS8/APPL2/FERMT2/PLEK2/PLXND1/DIAPH1/GABRA3/PDXP/KSR1/VEZT/FERMT1/SH3YL1/MYO1D/TLN1	28
CC	GO:0031527	filopodium membrane	5/2382	18/19717	0.05712	0.2872	0.2443	PDPN/ARF6/HLA-G/MYO10/TBC1D10C	5
CC	GO:0000307	cyclin-dependent protein kinase holoenzyme complex	9/2382	42/19717	0.06009	0.3	0.2552	CDK6/CCND1/CCNO/CCNG2/CCNG1/CCNJL/CDKN1A/MNAT1/CDK7	9
CC	GO:0044304	main axon	13/2382	68/19717	0.06156	0.3052	0.2596	ADORA2A/TNFRSF1B/CNTNAP1/NAV1/ANK3/MBP/EPB41L3/GJC2/MAP1A/DAGLA/ADORA1/DLG4/MYO1D	13
CC	GO:0031461	cullin-RING ubiquitin ligase complex	26/2382	158/19717	0.06248	0.3076	0.2617	ZSWIM4/FBXL2/KLHL3/CDC16/DDA1/ENC1/FBXL6/NCCRP1/ARIH2/CAND1/DDB2/ARIH1/DCAF16/SPSB1/ANAPC13/TRIM21/CRBN/FBXW4/KLHL20/DET1/KLHL13/FBXO17/DCAF12L2/FBXL5/CDC23/UBE2S	26
CC	GO:0098685	Schaffer collateral - CA1 synapse	15/2382	82/19717	0.06523	0.3168	0.2695	FYN/STX3/AKAP12/CDK5/PFN2/SLC30A1/DGKI/P2RX3/ACTB/STXBP5/PPP3CA/NPTN/STAT3/DVL1/ACTG1	15
CC	GO:0043209	myelin sheath	10/2382	49/19717	0.06524	0.3168	0.2695	AKR1B1/JAM3/SRD5A1/MBP/GJC2/GSN/GDI1/MPDZ/TSPAN2/MYO1D	10
CC	GO:0098984	neuron to neuron synapse	52/2382	350/19717	0.0666	0.3212	0.2733	ADORA2A/PRR7/SIPA1L1/DBN1/EEF2K/FYN/BMPR2/BACE1/CRYAB/EPB41L3/PPP1R9B/RPL7/LIN7A/PLCB4/CNN3/CDK5/ADORA1/SNAP47/VPS35/ARF1/SLC30A1/EPS8/DGKI/P2RX3/PDLIM5/DLG4/CAP2/PKP4/LRFN4/SYT1/GRIK4/RTN4/NPTN/GRIN3A/SAMD14/PDE4B/MPDZ/FXR2/VAMP7/ACTR2/SIGMAR1/PJA2/CNIH2/SEMA4F/MIB1/STAT3/DVL1/LIN7C/TMEM108/RGS7BP/HOMER2/RPS18	52
CC	GO:0005635	nuclear envelope	67/2382	464/19717	0.06866	0.3289	0.2798	WTAP/MX1/PTGES/ERN1/LPIN1/PGRMC2/MX2/LMO7/MYOF/ANXA11/PAK1/IL15RA/PLA2G4C/SORT1/PDE4D/NUP133/CHMP4B/LMNA/GCH1/SMOX/ABCF1/TM7SF2/DMPK/SDCBP/RAB40B/MAD1L1/NXF1/DCTN1/SEPHS1/GATA6/NUDT1/KPNA3/IGF2R/STAT6/AKIRIN1/SIRT1/OSBPL3/QSOX2/ANXA4/BCL2L1/RANBP3L/SLC30A1/P2RX3/RBM15/TOR3A/PARP11/RTN4/ABL1/NXT1/DPY19L4/TOR1A/MRGPRF/HTATIP2/MNS1/SIGMAR1/RANBP17/SPIN1/NUP35/MGST2/ROGDI/P2RX7/BICD2/UNC50/TMEM33/NUP62CL/XPO7/DDX19A	67
CC	GO:0016514	SWI/SNF complex	5/2382	19/19717	0.07009	0.3313	0.2818	SMARCD3/SMARCA2/ARID1A/NCR1/SMARCE1	5
CC	GO:0098644	complex of collagen trimers	5/2382	19/19717	0.07009	0.3313	0.2818	COL1A1/COL5A2/COL4A1/COL1A2/COL5A1	5
CC	GO:0030140	trans-Golgi network transport vesicle	7/2382	31/19717	0.07244	0.3401	0.2893	SORT1/CLTC/IGF2R/TMED9/TMED10/STEAP2/RASSF9	7
CC	GO:0030669	clathrin-coated endocytic vesicle membrane	9/2382	44/19717	0.07696	0.3539	0.3011	EPS15/SGIP1/FZD2/HBEGF/CLTC/WNT5A/FZD4/HLA-DQB1/PICALM	9
CC	GO:0017053	transcriptional repressor complex	15/2382	84/19717	0.07735	0.3539	0.3011	RELB/RCOR3/CCND1/HDGF/DDX20/RCOR2/JAZF1/SMARCA5/DR1/CHD4/SIRT1/CORO2A/NCOR2/TBL1XR1/ARID4A	15
CC	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	21/2382	126/19717	0.07825	0.3539	0.3011	TAP1/TAP2/ANPEP/MAN1A1/BET1/TGFA/GJB2/ROBO1/MYO18A/CLN8/SERPINH1/MPPE1/INPP5B/TMED9/TMED10/TAPBP/ERGIC1/CNIH2/PRRG4/SERPINA1/RER1	21
CC	GO:0030673	axolemma	4/2382	14/19717	0.07886	0.3539	0.3011	ADORA2A/EPB41L3/ADORA1/MYO1D	4
CC	GO:0038201	TOR complex	4/2382	14/19717	0.07886	0.3539	0.3011	SESN1/SESN3/SESN2/PRR5	4
CC	GO:0042588	zymogen granule	4/2382	14/19717	0.07886	0.3539	0.3011	STX3/DMBT1/TMED10/CLCA1	4
CC	GO:0043218	compact myelin	4/2382	14/19717	0.07886	0.3539	0.3011	AKR1B1/JAM3/MBP/MPDZ	4
CC	GO:0005782	peroxisomal matrix	10/2382	51/19717	0.08156	0.3614	0.3075	ACOX2/IDH1/NUDT7/CROT/AMACR/LONP2/ACOT8/SCP2/FAR1/ACOXL	10
CC	GO:0031907	microbody lumen	10/2382	51/19717	0.08156	0.3614	0.3075	ACOX2/IDH1/NUDT7/CROT/AMACR/LONP2/ACOT8/SCP2/FAR1/ACOXL	10
CC	GO:0099572	postsynaptic specialization	51/2382	348/19717	0.08281	0.3647	0.3102	ADORA2A/PRR7/SIPA1L1/DBN1/EEF2K/FYN/BMPR2/CRYAB/EPB41L3/PPP1R9B/RPL7/LIN7A/PLCB4/CNN3/CDK5/ADORA1/SNAP47/VPS35/ARF1/SLC30A1/EPS8/DGKI/PDLIM5/CHRNB1/DLG4/CAP2/PKP4/LRFN4/GABRA3/RTN4/NPTN/GRIN3A/SAMD14/PDE4B/MPDZ/FXR2/KCND3/ACTR2/KPNA2/SIGMAR1/PJA2/CNIH2/SEMA4F/MIB1/STAT3/DVL1/LIN7C/TMEM108/RGS7BP/HOMER2/RPS18	51
CC	GO:0005921	gap junction	7/2382	32/19717	0.08349	0.3654	0.3108	GJD3/DBN1/PANX1/PANX2/GJC2/GJB2/TJP1	7
CC	GO:0005868	cytoplasmic dynein complex	5/2382	20/19717	0.08454	0.3677	0.3128	SNX4/DYNC2LI1/DYNLL1/TOPORS/DYNLT3	5
CC	GO:0070382	exocytic vesicle	32/2382	207/19717	0.0852	0.3683	0.3134	NKD2/VAMP4/STX3/BACE1/STX6/WDR7/PPT1/DPYSL3/RAB4A/SYPL2/SNAP47/RAB3A/COPS4/BCL2L1/SYT4/DGKI/SYTL4/RPH3A/DLG4/STXBP5/SYT1/STX16/TMED9/PDE4B/VDAC1/TOR1A/TRAPPC4/VAMP7/ROGDI/IGF1/PICALM/VPS45	32
CC	GO:0061695	transferase complex, transferring phosphorus-containing groups	39/2382	259/19717	0.08609	0.3687	0.3136	ERN1/CDK6/PRPS1/PIK3CD/PRPS1L1/SOCS1/SOCS3/IRS1/CCND1/POLR3GL/PIK3R2/CCNO/ERCC2/PIK3R3/PHKB/CCNG2/CDK5/PRIM2/POLR3D/SESN2/TAF13/CCNG1/SOCS2/PRKAB2/TAF7L/MMS19/GTF2H5/SETD5/TAF6L/CCNJL/POLR3K/CDKN1A/PHKA2/MNAT1/SIK1/POLR1C/GTF2F2/CDK7/TADA3	39
CC	GO:0031901	early endosome membrane	24/2382	149/19717	0.08632	0.3687	0.3136	PDLIM4/EHD4/HLA-E/HLA-F/EPS15/SNX4/ITCH/HLA-A/RAB4A/EHD1/CLIP3/ARF6/APPL2/PLEKHF2/INPP5B/HLA-G/WDR91/HSD17B6/RAB31/HLA-B/GRIPAP1/HLA-H/TMEM165/SNX3	24
CC	GO:0030426	growth cone	27/2382	171/19717	0.08772	0.3724	0.3168	TUBB3/FSCN1/GDPD5/BASP1/ZFYVE27/DBN1/AUTS2/STX3/SSH1/RUFY3/ITGA4/DPYSL3/STMN3/CDK5/EPS8/FLRT3/TIAM2/TSHZ3/CBX6/TOR1A/TMOD2/SIGMAR1/PALLD/MYH10/DVL1/USP9X/NGEF	27
CC	GO:0070820	tertiary granule	26/2382	164/19717	0.08902	0.3757	0.3196	CXCL1/OLR1/TNFAIP6/PLD1/CNN2/CTSS/FRMPD3/PLAU/CD58/FTH1/IDH1/CYBA/GSDMD/SIRPA/METTL7A/PRG3/MMP9/DYNLL1/PTX3/DIAPH1/HBB/TBC1D10C/CSTB/ALDOC/UBR4/ADAM8	26
CC	GO:0080008	Cul4-RING E3 ubiquitin ligase complex	7/2382	33/19717	0.09545	0.4004	0.3406	DDA1/DDB2/ARIH1/DCAF16/CRBN/DET1/DCAF12L2	7
CC	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex	4/2382	15/19717	0.09767	0.4023	0.3422	DR1/KAT2B/YEATS2/TADA3	4
CC	GO:0071565	nBAF complex	4/2382	15/19717	0.09767	0.4023	0.3422	SMARCD3/SMARCA2/ARID1A/SMARCE1	4
CC	GO:0032587	ruffle membrane	16/2382	94/19717	0.09812	0.4023	0.3422	PDPN/PSD4/CORO1C/PAK1/WWC1/DDX58/PPP1R9B/PLEKHO1/EPS8/APPL2/DIAPH1/PDXP/KSR1/FERMT1/SH3YL1/TLN1	16
CC	GO:0062023	collagen-containing extracellular matrix	58/2382	406/19717	0.09868	0.4023	0.3422	ICAM1/THBS2/SERPINB8/NDP/NTN1/PLSCR1/ANXA11/CTSS/LAMB1/COL1A1/GPC4/C17orf58/VCAN/VWF/HDGF/HSPG2/THBS1/ANXA8/SCARA3/NAV2/COL5A2/CCDC80/TGFB2/PRG3/SDC2/WNT5B/MMP9/NID2/WNT5A/ANXA4/SULF1/COL6A3/GDF15/TNC/LOXL1/FBN1/SPARC/ITIH1/SERPINH1/SERPINB1/ZP2/LTBP2/COL16A1/COL4A1/MEGF9/SERPINE1/COL24A1/COL1A2/MUC17/NPPA/FGF10/FLG/SERPINA3/CSTB/ITGA6/SERPINA1/SERPINF2/COL5A1	58
CC	GO:0005942	phosphatidylinositol 3-kinase complex	6/2382	27/19717	0.09891	0.4023	0.3422	PIK3CD/SOCS1/SOCS3/PIK3R2/PIK3R3/SOCS2	6
CC	GO:0031526	brush border membrane	10/2382	53/19717	0.1002	0.4023	0.3422	SLC11A2/ATP8B1/SLC7A11/LIMA1/NPC1L1/GNA13/GNA12/ABCC2/CYBRD1/SLC26A3	10
CC	GO:0000930	gamma-tubulin complex	5/2382	21/19717	0.1004	0.4023	0.3422	CEP290/TOPORS/MARK4/PDE4B/TUBGCP4	5
CC	GO:0032806	carboxy-terminal domain protein kinase complex	5/2382	21/19717	0.1004	0.4023	0.3422	ERCC2/MMS19/GTF2H5/MNAT1/CDK7	5
CC	GO:0072686	mitotic spindle	18/2382	109/19717	0.1041	0.4146	0.3527	EML1/PKD2/CLTC/GPSM2/MAD1L1/CDC14B/HECW2/CKAP2L/YEATS2/GEM/DYNLL1/PKP4/DIAPH1/CDC42/TBL1XR1/MAPKBP1/TADA3/DYNLT3	18
CC	GO:0014069	postsynaptic density	47/2382	324/19717	0.105	0.4157	0.3537	ADORA2A/PRR7/SIPA1L1/DBN1/EEF2K/FYN/BMPR2/CRYAB/EPB41L3/PPP1R9B/RPL7/LIN7A/PLCB4/CNN3/CDK5/ADORA1/SNAP47/VPS35/ARF1/SLC30A1/EPS8/DGKI/PDLIM5/DLG4/CAP2/PKP4/LRFN4/RTN4/NPTN/GRIN3A/SAMD14/PDE4B/MPDZ/FXR2/ACTR2/SIGMAR1/PJA2/CNIH2/SEMA4F/MIB1/STAT3/DVL1/LIN7C/TMEM108/RGS7BP/HOMER2/RPS18	47
CC	GO:0000164	protein phosphatase type 1 complex	3/2382	10/19717	0.1104	0.4299	0.3657	PPP1R15A/PPP1R9B/SHOC2	3
CC	GO:0031010	ISWI-type complex	3/2382	10/19717	0.1104	0.4299	0.3657	C17orf49/SMARCA5/BPTF	3
CC	GO:0031313	extrinsic component of endosome membrane	3/2382	10/19717	0.1104	0.4299	0.3657	WDR91/GRIPAP1/SNX10	3
CC	GO:0005643	nuclear pore	15/2382	89/19717	0.1137	0.4391	0.3736	MX2/NUP133/MAD1L1/NXF1/KPNA3/RANBP3L/PARP11/NXT1/RANBP17/NUP35/BICD2/TMEM33/NUP62CL/XPO7/DDX19A	15
CC	GO:0030427	site of polarized growth	27/2382	176/19717	0.114	0.4391	0.3736	TUBB3/FSCN1/GDPD5/BASP1/ZFYVE27/DBN1/AUTS2/STX3/SSH1/RUFY3/ITGA4/DPYSL3/STMN3/CDK5/EPS8/FLRT3/TIAM2/TSHZ3/CBX6/TOR1A/TMOD2/SIGMAR1/PALLD/MYH10/DVL1/USP9X/NGEF	27
CC	GO:0016460	myosin II complex	5/2382	22/19717	0.1177	0.4486	0.3816	MYL5/MYOM1/MYH6/MYH9/MYH10	5
CC	GO:0042629	mast cell granule	5/2382	22/19717	0.1177	0.4486	0.3816	AKR1B1/KIT/PIK3CD/SRGN/NPPA	5
CC	GO:0032279	asymmetric synapse	47/2382	328/19717	0.1214	0.4604	0.3917	ADORA2A/PRR7/SIPA1L1/DBN1/EEF2K/FYN/BMPR2/CRYAB/EPB41L3/PPP1R9B/RPL7/LIN7A/PLCB4/CNN3/CDK5/ADORA1/SNAP47/VPS35/ARF1/SLC30A1/EPS8/DGKI/PDLIM5/DLG4/CAP2/PKP4/LRFN4/RTN4/NPTN/GRIN3A/SAMD14/PDE4B/MPDZ/FXR2/ACTR2/SIGMAR1/PJA2/CNIH2/SEMA4F/MIB1/STAT3/DVL1/LIN7C/TMEM108/RGS7BP/HOMER2/RPS18	47
CC	GO:0033267	axon part	54/2382	382/19717	0.1231	0.4621	0.3931	TUBB3/ADORA2A/HSPB1/FSCN1/GDPD5/BASP1/ZFYVE27/TNFRSF1B/DBN1/AUTS2/CNTNAP1/NAV1/STX3/ANK3/SSH1/RUFY3/ITGA4/MBP/DPYSL3/ROR1/STMN3/EPB41L3/GJC2/ITGA2/MAP1A/DAGLA/CDK5/ADORA1/RAB3A/EPS8/DGKI/P2RX3/ACTB/FLRT3/TIAM2/DYNLL1/ACTR10/BRSK2/DLG4/TSHZ3/CBX6/TOR1A/AP3S1/TMOD2/SIGMAR1/PALLD/MYH10/MYO1D/DVL1/ACTG1/SRI/TMEM108/USP9X/NGEF	54
CC	GO:0070603	SWI/SNF superfamily-type complex	13/2382	76/19717	0.1232	0.4621	0.3931	C17orf49/SMARCD3/SMARCA5/SMARCA2/CHD4/INO80C/ARID1A/PBRM1/NCR1/EN2/SMARCE1/BPTF/PHF10	13
CC	GO:0005741	mitochondrial outer membrane	27/2382	178/19717	0.1257	0.4666	0.397	BID/GK/SLC11A2/LPIN1/RSAD2/PPP1R15A/HK2/ACACB/BCL2L2/BPHL/CYP27B1/DMPK/PMAIP1/CPT1A/QTRT1/TOMM34/ACSL5/ARMCX2/CYB5A/RAB32/BCL2L1/CYB5B/ASS1/GPAM/VDAC1/UBB/STARD7	27
CC	GO:0044452	nucleolar part	27/2382	178/19717	0.1257	0.4666	0.397	DAB2/NFKBIE/RSAD2/SESN1/LIPA/JAZF1/SMARCA5/ACACA/CDCA7L/NUAK1/TMEM217/RPAIN/FAM111A/INO80C/FOXJ2/PAFAH1B2/ICK/UBD/EN2/DDX46/IMP3/BTBD10/POLR1C/BOP1/URB1/AKNA/NFIB	27
CC	GO:0099738	cell cortex region	8/2382	42/19717	0.1273	0.4701	0.3999	PKD2/GPSM2/DCTN1/PHLDB1/TCHP/PHLDB2/PPFIA3/EPB41L2	8
CC	GO:0044665	MLL1/2 complex	6/2382	29/19717	0.1295	0.4709	0.4006	C17orf49/E2F6/INO80C/RBBP5/MAX/HCFC2	6
CC	GO:0071339	MLL1 complex	6/2382	29/19717	0.1295	0.4709	0.4006	C17orf49/E2F6/INO80C/RBBP5/MAX/HCFC2	6
CC	GO:0005795	Golgi stack	23/2382	149/19717	0.1295	0.4709	0.4006	ST3GAL1/COG2/BET1/B4GALT3/SORT1/SULF2/YIPF6/CSGALNACT1/CSGALNACT2/CLIP3/TMBIM4/PSENEN/SULF1/ATL1/MGAT2/GCNT1/GOLGA8G/ST3GAL3/STX16/TRAPPC4/GALNT1/ST3GAL4/ASAP2	23
CC	GO:0045334	clathrin-coated endocytic vesicle	11/2382	63/19717	0.1331	0.4795	0.408	EPS15/SGIP1/MYO1E/FZD2/HBEGF/CLTC/WNT5A/FZD4/HLA-DQB1/DVL2/PICALM	11
CC	GO:0045211	postsynaptic membrane	46/2382	323/19717	0.1332	0.4795	0.408	PDLIM4/ADORA2A/PRR7/SIPA1L1/DBN1/ANK3/F2R/MAGEE1/LIN7A/GRIA3/HTR3B/DAGLA/CDK5/ADORA1/KCNB1/ARF1/LHFPL4/SLC30A1/DGKI/FLRT3/PDLIM5/RPH3A/CHRNB1/DLG4/DAGLB/LRFN4/GRM2/GABRA3/GRIK4/NPTN/GRIN3A/MPDZ/KCND3/KPNA2/SIGMAR1/PJA2/PCDHB13/CNIH2/SEMA4F/LIN7C/PCDH17/TMEM108/RGS7BP/HOMER2/CRKL/PICALM	46
CC	GO:0001772	immunological synapse	7/2382	36/19717	0.1366	0.4846	0.4123	ICAM1/DUSP3/HAVCR2/NPTN/BCL10/MYH9/PDCD6IP	7
CC	GO:0008180	COP9 signalosome	7/2382	36/19717	0.1366	0.4846	0.4123	BASP1/FLOT1/AMOTL1/COPS4/DYNLL1/MYH9/EPB41L2	7
CC	GO:0005652	nuclear lamina	3/2382	11/19717	0.1387	0.4846	0.4123	LMNA/NARF/NUP35	3
CC	GO:0043220	Schmidt-Lanterman incisure	3/2382	11/19717	0.1387	0.4846	0.4123	AKR1B1/JAM3/MPDZ	3
CC	GO:0005666	RNA polymerase III complex	4/2382	17/19717	0.1407	0.4846	0.4123	POLR3GL/POLR3D/POLR3K/POLR1C	4
CC	GO:0016282	eukaryotic 43S preinitiation complex	4/2382	17/19717	0.1407	0.4846	0.4123	EIF1/DHX29/EIF3E/EIF1B	4
CC	GO:0031092	platelet alpha granule membrane	4/2382	17/19717	0.1407	0.4846	0.4123	LHFPL2/PHACTR2/SYTL4/SPARC	4
CC	GO:0016235	aggresome	8/2382	43/19717	0.1408	0.4846	0.4123	SQSTM1/EPS15/TRIM37/HSPB7/SERGEF/HOXD3/UBD/DVL2	8
CC	GO:1902562	H4 histone acetyltransferase complex	8/2382	43/19717	0.1408	0.4846	0.4123	DR1/KAT2B/MORF4L2/YEATS2/ACTB/MSL1/MSL3/TADA3	8
CC	GO:0032421	stereocilium bundle	10/2382	57/19717	0.1441	0.4937	0.42	ATP8B1/IDO1/RDX/BBS2/EPS8/DOCK4/KPTN/PCDH15/VEZT/HOMER2	10
CC	GO:0016592	mediator complex	7/2382	37/19717	0.152	0.518	0.4407	MED10/MED13L/HAVCR2/CDK8/MED8/MED9/MED20	7
CC	GO:0016459	myosin complex	11/2382	65/19717	0.1558	0.5252	0.4468	CGNL1/MYL5/MYO1E/MYOM1/MYO18A/MYO10/MYH6/MYH9/MYH10/MYO1D/MYL12A	11
CC	GO:0097386	glial cell projection	5/2382	24/19717	0.156	0.5252	0.4468	AKR1B1/SLC7A11/FYN/GJB2/SYT4	5
CC	GO:0030286	dynein complex	9/2382	51/19717	0.1563	0.5252	0.4468	SNX4/DYNC2LI1/WDR63/DCTN1/WDR78/DYNLL1/TOPORS/DNAH6/DYNLT3	9
CC	GO:0008021	synaptic vesicle	28/2382	191/19717	0.1613	0.5377	0.4574	VAMP4/STX3/BACE1/STX6/WDR7/PPT1/RAB4A/SYPL2/SNAP47/RAB3A/COPS4/BCL2L1/SYT4/DGKI/RPH3A/DLG4/STXBP5/SYT1/STX16/TMED9/PDE4B/VDAC1/TOR1A/TRAPPC4/VAMP7/ROGDI/PICALM/VPS45	28
CC	GO:0070993	translation preinitiation complex	4/2382	18/19717	0.1646	0.5377	0.4574	EIF1/DHX29/EIF3E/EIF1B	4
CC	GO:0043197	dendritic spine	25/2382	169/19717	0.1658	0.5377	0.4574	PDLIM4/SIPA1L1/APBA3/EEF2K/CRYAB/PPP1R9B/LPAR1/CNN3/ITPKA/ADORA1/DGKI/P2RX3/RPH3A/DLG4/ASAP1/PPP3CA/PDE4B/FXR2/FARP1/CDC42/CNIH2/MYH10/DVL1/SRI/NEDD4	25
CC	GO:0018995	host	12/2382	73/19717	0.166	0.5377	0.4574	GBP2/IFIT1/NUP133/GBP4/VPS37D/VPS37C/KPNA3/AXL/UBB/KPNA2/NUP35/NMT2	12
CC	GO:0043657	host cell	12/2382	73/19717	0.166	0.5377	0.4574	GBP2/IFIT1/NUP133/GBP4/VPS37D/VPS37C/KPNA3/AXL/UBB/KPNA2/NUP35/NMT2	12
CC	GO:0005614	interstitial matrix	3/2382	12/19717	0.1691	0.5377	0.4574	NAV2/CCDC80/TNC	3
CC	GO:0017119	Golgi transport complex	3/2382	12/19717	0.1691	0.5377	0.4574	COG2/CDC42/COG5	3
CC	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	3/2382	12/19717	0.1691	0.5377	0.4574	ARIH1/CRBN/DET1	3
CC	GO:0032009	early phagosome	3/2382	12/19717	0.1691	0.5377	0.4574	APPL2/RAB31/SNX3	3
CC	GO:0033270	paranode region of axon	3/2382	12/19717	0.1691	0.5377	0.4574	CNTNAP1/EPB41L3/GJC2	3
CC	GO:0061700	GATOR2 complex	3/2382	12/19717	0.1691	0.5377	0.4574	SESN1/SESN3/SESN2	3
CC	GO:0097449	astrocyte projection	3/2382	12/19717	0.1691	0.5377	0.4574	SLC7A11/GJB2/SYT4	3
CC	GO:0032420	stereocilium	9/2382	52/19717	0.1701	0.5383	0.4579	ATP8B1/RDX/BBS2/EPS8/DOCK4/KPTN/PCDH15/VEZT/HOMER2	9
CC	GO:0044309	neuron spine	25/2382	171/19717	0.181	0.5705	0.4853	PDLIM4/SIPA1L1/APBA3/EEF2K/CRYAB/PPP1R9B/LPAR1/CNN3/ITPKA/ADORA1/DGKI/P2RX3/RPH3A/DLG4/ASAP1/PPP3CA/PDE4B/FXR2/FARP1/CDC42/CNIH2/MYH10/DVL1/SRI/NEDD4	25
MF	GO:0019787	ubiquitin-like protein transferase activity	87/2275	407/17697	9.102e-07	0.0007032	0.0006427	BIRC3/TNFAIP3/HERC6/SH3RF1/UBE2L6/BIRC2/FBXL2/LMO7/RNF145/RNF170/RNF20/LNX1/TRAF3/UBE4A/MED10/ANKIB1/TRIM25/PDZRN3/TRIM37/TRIM47/ITCH/RNF14/ZFP91/UBA7/FBXL6/NCCRP1/UBR5/UBE2Q2/UBE2M/ARIH2/HECTD1/DDB2/HECW2/UBR1/ASB1/PPIL2/ARIH1/HLTF/RNF5/NSMCE2/RNF141/ZMIZ2/TRAF2/TRIM21/RNF144B/UBE2E1/TRIM2/UBE2T/RNF4/FBXL22/TOPORS/HERC5/KLHL20/BIRC6/RNF149/TRIM6/KLHL13/FBXO3/FBXO17/KIAA1586/RBCK1/ASB2/MED20/RNF212/PJA2/CDC42/UBE2Z/SH3RF2/FBXL5/CDC23/MIB1/UBE4B/CBLB/MYCBP2/RNF121/UBR4/MYLIP/ZNF451/RNF126/PELI2/NEDD4/PIAS3/BFAR/MAGEL2/UBE2S/PELI3/ZNF598	87
MF	GO:0004298	threonine-type endopeptidase activity	12/2275	21/17697	1.89e-06	0.0007032	0.0006427	PSMA6/PSMB10/PSMB8/PSMB7/PSMB9/PSMA3/PSMA1/PSMB2/PSMB3/TASP1/PSMA8/PSMB5	12
MF	GO:0070003	threonine-type peptidase activity	12/2275	21/17697	1.89e-06	0.0007032	0.0006427	PSMA6/PSMB10/PSMB8/PSMB7/PSMB9/PSMA3/PSMA1/PSMB2/PSMB3/TASP1/PSMA8/PSMB5	12
MF	GO:0004842	ubiquitin-protein transferase activity	81/2275	382/17697	2.977e-06	0.0008306	0.0007592	BIRC3/TNFAIP3/HERC6/SH3RF1/UBE2L6/BIRC2/FBXL2/LMO7/RNF145/RNF170/RNF20/LNX1/TRAF3/UBE4A/MED10/ANKIB1/TRIM25/PDZRN3/TRIM37/TRIM47/ITCH/RNF14/ZFP91/UBA7/FBXL6/NCCRP1/UBR5/UBE2Q2/UBE2M/ARIH2/HECTD1/DDB2/HECW2/UBR1/ASB1/PPIL2/ARIH1/HLTF/RNF5/RNF141/TRAF2/TRIM21/RNF144B/UBE2E1/TRIM2/UBE2T/RNF4/FBXL22/TOPORS/HERC5/KLHL20/BIRC6/RNF149/TRIM6/KLHL13/FBXO3/FBXO17/RBCK1/ASB2/MED20/PJA2/CDC42/UBE2Z/SH3RF2/FBXL5/CDC23/MIB1/UBE4B/CBLB/MYCBP2/RNF121/UBR4/MYLIP/RNF126/PELI2/NEDD4/BFAR/MAGEL2/UBE2S/PELI3/ZNF598	81
MF	GO:0003779	actin binding	88/2275	431/17697	5.672e-06	0.001266	0.001157	FLNC/PDLIM4/PLS3/NEXN/FSCN1/ARPC1A/DBN1/KLHL3/CORO1C/PANX1/CNN2/MARCKSL1/VCL/LIMA1/ACTR3/MPRIP/CALD1/SSH1/SHROOM3/GBP1/ENC1/ANXA8/CCDC88A/FMN2/MYO1E/STK38L/RDX/MYOM1/DSTN/DIXDC1/IPP/KLHL5/EPB41L3/PPP1R9B/PLEKHH2/FMNL2/FGD4/MAP1A/PHACTR2/FHOD1/FLNB/DAAM2/ZNF185/CNN3/TPM4/ARPC2/ENAH/CAPZA2/MYO18A/SHROOM2/MICAL3/MYOM3/PFN2/MYLK/EPS8/GSN/CORO2A/PDLIM5/YWHAH/PXK/ACTN4/FERMT2/CAP2/KLHL20/EPB41L1/DIAPH1/PDLIM2/SNTA1/KPTN/GMFB/ABL1/SAMD14/MYO10/ACTR2/TMOD2/MYH6/LSP1/SNTB1/PALLD/FERMT1/MYH9/MYH10/MYO1D/TLN1/HOMER2/WASF2/EPB41L2/PDLIM3	88
MF	GO:0005125	cytokine activity	50/2275	220/17697	3.486e-05	0.006485	0.005927	CXCL1/CXCL2/CXCL6/CCL20/BMP2/NAMPT/CCL5/IL6/IL32/CXCL5/CD70/CSF2/IL1B/LIF/CXCL10/IL33/CCL2/CCL8/NDP/IL1A/CSF1/CCL7/TNFSF9/FGF2/PF4V1/VEGFA/BMP4/TNFSF13B/IL12A/CCL3L3/GREM2/CXCL3/IL26/CXCL11/CCL3/IL15/EDN1/CXCL9/INHBB/CCL1/TGFB2/EBI3/CLCF1/GDF5/WNT5A/GDF15/TNF/TNFRSF11B/GDF6/CMTM8	50
MF	GO:0061659	ubiquitin-like protein ligase activity	51/2275	230/17697	5.815e-05	0.009271	0.008473	BIRC3/SH3RF1/BIRC2/RNF145/RNF170/UBE4A/MED10/ANKIB1/TRIM25/PDZRN3/TRIM37/ITCH/RNF14/FBXL6/NCCRP1/UBR5/ARIH2/HECW2/UBR1/ASB1/PPIL2/ARIH1/HLTF/RNF5/ZMIZ2/RNF144B/TRIM2/FBXL22/TOPORS/RNF149/TRIM6/FBXO17/KIAA1586/ASB2/MED20/PJA2/CDC42/SH3RF2/UBE4B/CBLB/MYCBP2/RNF121/MYLIP/ZNF451/RNF126/PELI2/NEDD4/PIAS3/BFAR/PELI3/ZNF598	51
MF	GO:0008009	chemokine activity	17/2275	49/17697	7.431e-05	0.01037	0.009475	CXCL1/CXCL2/CXCL6/CCL20/CCL5/CXCL5/CXCL10/CCL2/CCL8/CCL7/PF4V1/CCL3L3/CXCL3/CXCL11/CCL3/CXCL9/CCL1	17
MF	GO:0042379	chemokine receptor binding	20/2275	66/17697	0.0001554	0.01887	0.01725	CXCL1/CXCL2/CXCL6/CCL20/CCL5/CXCL5/CXCL10/CCL2/CCL8/CCL7/PF4V1/STAT1/CCL3L3/CXCL3/CXCL11/CCL3/ITCH/CXCL9/CCL1/STAT3	20
MF	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	13/2275	34/17697	0.0001691	0.01887	0.01725	MTHFD2L/APOBEC3G/ADAR/AMPD3/GCH1/ADA/APOBEC3H/MTHFD2/CDADC1/ADARB1/APOBEC3F/ZBP1/ADAT1	13
MF	GO:0005126	cytokine receptor binding	58/2275	286/17697	0.0002536	0.02573	0.02351	CXCL1/CXCL2/CXCL6/CCL20/BMP2/BID/CCL5/IL6/CXCL5/CD70/CSF2/IL1B/LIF/CXCL10/CCL2/CCL8/IL1A/CSF1/CCL7/TNFSF9/PF4V1/STAT1/IL6ST/VEGFA/IRAK4/CFLAR/BMP4/TNFSF13B/TRAF3/IL12A/CCL3L3/CXCL3/CXCL11/CCL3/TRIM37/FADD/ITCH/TRIP6/IL15/CXCL9/INHBB/SDCBP/CCL1/TGFB2/EBI3/CLCF1/GDF5/TRAF2/GDF15/TYK2/TNF/PGF/FKBP1A/SOCS2/GATA3/ENG/GDF6/STAT3	58
MF	GO:0061630	ubiquitin protein ligase activity	47/2275	221/17697	0.0003106	0.02888	0.0264	BIRC3/SH3RF1/BIRC2/RNF145/RNF170/UBE4A/MED10/ANKIB1/TRIM25/PDZRN3/TRIM37/ITCH/RNF14/FBXL6/NCCRP1/UBR5/ARIH2/HECW2/UBR1/ASB1/PPIL2/ARIH1/HLTF/RNF5/RNF144B/TRIM2/FBXL22/TOPORS/RNF149/TRIM6/FBXO17/ASB2/MED20/PJA2/CDC42/SH3RF2/UBE4B/CBLB/MYCBP2/RNF121/MYLIP/RNF126/PELI2/NEDD4/BFAR/PELI3/ZNF598	47
MF	GO:0019208	phosphatase regulator activity	25/2275	96/17697	0.0003616	0.02899	0.0265	BMP2/ENSA/PPP4R4/PPP1R15A/PPP2R1B/SET/CALM1/PPP1R12A/DMPK/PPP1R9B/PHACTR2/RCAN1/PPP1R12C/BMP2K/PPP2R5E/CALM2/ANKLE2/PPP2R5C/SBF2/PPP1R14C/PPP1R7/SH3RF2/RCAN2/SHOC2/SBF1	25
MF	GO:0003725	double-stranded RNA binding	21/2275	75/17697	0.0003637	0.02899	0.0265	OAS1/IFIH1/MBNL1/OAS3/DDX60/OAS2/DDX58/ADAR/OASL/SLC3A2/DHX58/STAU2/CLTC/YRDC/EIF4A1/PRKRA/STAU1/TLR3/ADARB1/LRRFIP1/ZFR	21
MF	GO:0005516	calmodulin binding	43/2275	200/17697	0.0004296	0.03196	0.02921	PPP3CC/KCNN4/FBXL2/PDE1C/DAPK1/EEF2K/CNN2/MARCKSL1/RRAD/CALD1/CAMK2D/FAS/PDE1A/EDF1/MKNK2/MYO1E/MBP/RGS2/PHKB/ADCY3/RGS16/CNN3/GEM/ITPKA/RGS4/CAMKK2/MYLK/DDX5/CAMK2G/SYT1/PPP3CA/SNTA1/MYO10/ORAI1/PHKA2/MYH6/SNTB1/TJP1/MYH9/MYH10/MYO1D/UBR4/CAMSAP1	43
MF	GO:0001664	G protein-coupled receptor binding	56/2275	280/17697	0.0004607	0.03213	0.02937	CXCL1/CXCL2/CXCL6/CCL20/CCL5/CXCL5/CXCL10/CCL2/BDKRB2/CCL8/ADORA2A/NDP/CCL7/C3/PF4V1/STAT1/DNAJA1/CCL3L3/FZD1/CXCL3/FYN/PDE4D/CLIC6/CXCL11/CCL3/ITCH/EDN1/CXCL9/SDCBP/CCL1/GNA13/WNT5B/RTP4/CNRIP1/GNA12/WNT5A/ARRDC3/ADORA1/VPS35/TYK2/MRAP2/ATP2A2/DLG4/RSPO2/ARHGEF12/RALA/PTPN11/NPPA/STAT3/DVL1/DVL2/NEDD4/FZD7/HOMER2/PDCD6IP/ADRA2A	56
MF	GO:0030145	manganese ion binding	18/2275	62/17697	0.0005817	0.03819	0.0349	SOD2/DYRK2/NUDT7/PIM1/POMGNT1/NPEPL1/MGAT1/MGAT2/PPM1M/GYG1/MPPE1/FEN1/ME1/MPPED2/ABL1/GALNT4/ATP13A2/GALNT1	18
MF	GO:0050839	cell adhesion molecule binding	89/2275	499/17697	0.0007627	0.04729	0.04322	ICAM1/VCAM1/TBC1D2/IL1B/S1PR3/EHD4/FSCN1/FGF2/ISG15/PRKCA/FNBP1L/ESM1/DBN1/GPRC5A/STAT1/CNN2/JAM3/VCL/LAMB1/CDC42EP1/ARHGAP18/LIMA1/MPRIP/TRIM25/EPS15/CALD1/ITGB5/BMPR2/CHMP4B/ANK3/VWF/IDH1/ITGA4/TRIM29/THBS1/SLC3A2/MICALL1/RDX/PXN/KTN1/CAST/ITGB8/FMNL2/NISCH/ITGA2/FLNB/EHD1/S100A11/CNN3/ZC3H15/PHLDB2/ARHGAP1/DHX29/SERBP1/DCHS2/FBN1/EIF3E/PDLIM5/TACSTD2/ACTN4/PTPRM/PKP4/ASAP1/RPL15/COL16A1/CHMP5/RTN4/NPTN/LRRFIP1/LGALS8/ABCF3/MMP24/PPFIBP1/PTPN11/PKN2/TJP1/MYH9/IGF1/CDH4/ITGA6/ICAM5/TLN1/ITGBL1/COL5A1/ADAM8/CRKL/PCMT1/PICALM/WASF2	89
MF	GO:0070403	NAD+ binding	7/2275	14/17697	0.0008634	0.05072	0.04635	ALDH1A3/GLUD1/HADH/SIRT1/CRYL1/PARP15/SIRT6	7
MF	GO:0035091	phosphatidylinositol binding	49/2275	245/17697	0.001008	0.05622	0.05139	CYTH3/PLD1/PITPNC1/PLCD1/SNX30/ESYT1/ZCCHC14/PLEKHF1/SNX4/WIPI1/ANXA8/CCDC88A/MYO1E/GSDMD/SDCBP/VPS36/NISCH/PLEKHA3/ITPR2/TNFAIP8L3/TPCN1/WDFY1/PFN2/OSBPL5/SH3PXD2B/APPL2/RPH3A/PXK/FERMT2/PLEK2/PLEKHF2/ASAP1/MPPE1/SYT1/PIGK/WDR45/MYO10/SBF2/MITD1/ZFYVE19/ATP13A2/SH3YL1/TLN1/FZD7/PLEKHA4/SGK3/PICALM/SNX3/SNX10	49
MF	GO:0051427	hormone receptor binding	39/2275	185/17697	0.001147	0.06096	0.05571	PPARGC1A/CEBPB/NCOA7/DAXX/STAT1/RERG/FYN/RXRA/WIPI1/ZNHIT3/RNF14/SMARCD3/FHL2/TRIP6/OASL/TCF7L2/PTHLH/SLC30A9/VDR/SIRT1/NKX3-1/TYK2/DDX5/RNF4/YWHAH/ACTN4/SOCS2/TACC2/MMS19/ARID1A/NCOR2/SMARCE1/PPARG/PTPN11/NPPA/STAT3/CDK7/TADA3/NCOA6	39
MF	GO:0033549	MAP kinase phosphatase activity	7/2275	15/17697	0.00144	0.07305	0.06676	DUSP6/DUSP14/DUSP3/DUSP16/DUSP18/DUSP10/DUSP5	7
MF	GO:0070851	growth factor receptor binding	30/2275	134/17697	0.001532	0.07396	0.0676	IL6/CSF2/IL1B/ERN1/IL1A/FGF2/ESM1/PLSCR1/IL6ST/VEGFA/EREG/IRAK4/PDGFRB/IL12A/FYN/SNX4/TRIP6/TGFA/HBEGF/SDCBP/PDGFD/FLRT2/PGF/FLRT3/FGF5/PDGFC/GATA3/NPTN/FGF10/RNF126	30
MF	GO:0035257	nuclear hormone receptor binding	33/2275	152/17697	0.001591	0.07396	0.0676	PPARGC1A/CEBPB/NCOA7/DAXX/STAT1/RERG/RXRA/WIPI1/ZNHIT3/RNF14/SMARCD3/FHL2/TRIP6/OASL/TCF7L2/SLC30A9/VDR/SIRT1/NKX3-1/DDX5/RNF4/YWHAH/ACTN4/TACC2/MMS19/ARID1A/NCOR2/SMARCE1/PPARG/STAT3/CDK7/TADA3/NCOA6	33
MF	GO:0033293	monocarboxylic acid binding	17/2275	64/17697	0.002389	0.1066	0.09746	ACOX2/PRR7/PYGL/ACACB/CYP27C1/FABP3/RXRA/NR2F2/STX3/ADH5/IGF2R/VDR/NDUFAB1/SCP2/PPARG/ID3/ACOXL	17
MF	GO:0002020	protease binding	28/2275	128/17697	0.003077	0.1268	0.1159	TNFAIP3/CD70/RIPK2/BDKRB2/KIT/PANX1/CFLAR/COL1A1/VWF/FADD/MBP/CLTC/CAST/FLOT1/TIMP4/RAD23A/TNF/STIM1/MAGEA3/LONP2/SERPINE1/COL1A2/BCL10/CSTB/SRI/SERPINA1/SERPINF2/BFAR	28
MF	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	6/2275	13/17697	0.003431	0.1268	0.1159	DUSP6/DUSP14/DUSP16/DUSP18/DUSP10/DUSP5	6
MF	GO:0060590	ATPase regulator activity	12/2275	40/17697	0.003434	0.1268	0.1159	BAG2/DNAJA1/DNAJC19/FNIP2/FNIP1/RAB4A/DNAJC15/RAB3A/NCAPH/BRSK2/GRPEL1/GRPEL2	12
MF	GO:0035014	phosphatidylinositol 3-kinase regulator activity	7/2275	17/17697	0.003446	0.1268	0.1159	SOCS1/SOCS3/KLF4/PIK3R2/PIK3R3/SOCS2/WDR91	7
MF	GO:0042813	Wnt-activated receptor activity	7/2275	17/17697	0.003446	0.1268	0.1159	FZD1/ROR1/FZD2/LRP5/FZD8/FZD4/FZD7	7
MF	GO:0045296	cadherin binding	60/2275	331/17697	0.003523	0.1268	0.1159	TBC1D2/EHD4/FSCN1/FNBP1L/DBN1/GPRC5A/STAT1/CNN2/VCL/CDC42EP1/ARHGAP18/LIMA1/MPRIP/TRIM25/EPS15/CALD1/BMPR2/CHMP4B/ANK3/IDH1/TRIM29/SLC3A2/MICALL1/RDX/KTN1/CAST/FMNL2/FLNB/EHD1/S100A11/CNN3/ZC3H15/PHLDB2/ARHGAP1/DHX29/SERBP1/DCHS2/EIF3E/PDLIM5/TACSTD2/PTPRM/PKP4/ASAP1/RPL15/CHMP5/RTN4/LRRFIP1/ABCF3/MMP24/PPFIBP1/PKN2/TJP1/MYH9/CDH4/ITGA6/TLN1/CRKL/PCMT1/PICALM/WASF2	60
MF	GO:0051287	NAD binding	15/2275	56/17697	0.003855	0.1305	0.1193	GPD1L/ALDH1A3/IDH1/GLUD1/HADH/SIRT1/HIBADH/CRYL1/LDHB/PHGDH/ME1/BDH2/NUDT6/PARP15/SIRT6	15
MF	GO:0044325	ion channel binding	27/2275	124/17697	0.00386	0.1305	0.1193	ID2/BAG2/FHL1/GPD1L/PANX1/FYN/CALM1/HERPUD1/PDE4D/CAMK2D/PKD2/ANK3/GRINA/STAC/KCNB1/YWHAH/CALM2/ACTN4/FKBP1A/DIAPH1/NPTN/SNTA1/PDE4B/VDAC1/KCND3/PACS2/SRI	27
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	26/2275	119/17697	0.004308	0.1411	0.129	BMP2/AKR1B1/CBR3/HSD11B1/RDH10/RDH8/IDH1/DHRS11/DHRS3/HADH/ADH5/CBR4/IMPDH2/HIBADH/CRYL1/HSD17B12/HSD3B7/LDHB/HSD17B7/PHGDH/ME1/BDH2/HSD17B6/LDHD/RDH13/ADH1C	26
MF	GO:0050321	tau-protein kinase activity	8/2275	22/17697	0.004427	0.1411	0.129	SIK3/ROCK1/FYN/CDK5/BRSK2/ROCK2/MARK4/TAOK1	8
MF	GO:0031267	small GTPase binding	76/2275	443/17697	0.00498	0.1516	0.1385	TBC1D2/ABCA1/PLCE1/DENND5A/CORO1C/ROCK1/RAB3IL1/ARHGEF10/PAK1/RIN3/CDC42EP1/CDC42EP3/NET1/TBC1D4/MICALL1/RAB3GAP1/RABGAP1/SH3BP4/TBC1D22B/RAB11FIP2/FMNL2/FGD4/SERGEF/NPC1L1/ERRFI1/RHOBTB3/FGD1/EHD1/DAAM2/ITPKA/OPTN/EVI5L/ARHGAP1/RABGGTA/MICAL3/RIN2/RANBP3L/ARHGEF5/EPS8/DGKI/TIAM2/ARHGEF17/SYTL4/RPH3A/DOCK4/STXBP5/ARHGEF12/RALBP1/GDI1/DIAPH1/PLEKHG4/ROCK2/RAB11FIP1/TBC1D9B/NXT1/SBF2/ARHGDIB/TRAPPC4/FARP1/TBC1D10C/RANBP17/PKN2/RIN1/TBC1D8/RILPL1/DVL1/DVL2/MYCBP2/BICD2/NGEF/SBF1/PLEKHG2/ANKRD27/PICALM/XPO7/RCBTB2	76
MF	GO:0015605	organophosphate ester transmembrane transporter activity	9/2275	27/17697	0.005025	0.1516	0.1385	SLC25A24/ATP8B1/ABCD1/ATP8A2/SLC25A33/SLC37A1/SLC25A36/TMEM30B/ABCC11	9
MF	GO:0019207	kinase regulator activity	40/2275	207/17697	0.005182	0.1522	0.1391	CCL5/CXCL10/TRIB1/HSPB1/TRIB2/DAXX/GPRC5A/SOCS1/SOCS3/CALM1/CCND1/KLF4/ELP4/KIDINS220/PIK3R2/CCNO/STK4/TRIB3/PIK3R3/KAT2B/DNAJC3/HEXIM2/CCNG2/CDKN2C/MTCP1/CDKN1C/CCNYL1/CCNG1/CALM2/SOCS2/WDR91/ITPRIP/GMFB/BCL10/CCNJL/GAS6/PKIG/CDKN1A/MNAT1/TAOK1	40
MF	GO:0019239	deaminase activity	10/2275	32/17697	0.005323	0.1523	0.1392	APOBEC3G/ADAR/AMPD3/ADA/APOBEC3H/CDADC1/ADARB1/APOBEC3F/ZBP1/ADAT1	10
MF	GO:0003713	transcription coactivator activity	57/2275	319/17697	0.005949	0.1642	0.1501	NFKB2/PPARGC1A/CITED2/LPIN1/NCOA7/FGF2/BIRC2/DAXX/ARID5B/RNF20/NFKBIB/WWTR1/WWC1/RXRA/EDF1/NEUROG3/RNF14/SMARCD3/FHL2/SLC30A9/DR1/HIPK2/KAT2B/THRA/YAP1/SMARCA2/SERTAD2/CARM1/VDR/JUNB/ZMIZ2/RNF4/ACTN4/ELF3/SUB1/CEBPA/GATA3/TAF7L/MMS19/ARID1A/ABL1/BCL10/TAF6L/SMARCE1/MAX/HTATIP2/PPARG/MED20/TDRD3/TFDP1/POU2AF1/ARL2BP/CDK7/TADA3/HCFC2/NCOA6/CBFB	57
MF	GO:0051371	muscle alpha-actinin binding	8/2275	23/17697	0.006034	0.1642	0.1501	PDLIM4/PKD2/MYOM1/MYOM3/PDLIM5/PDLIM2/PALLD/PDLIM3	8
MF	GO:0004683	calmodulin-dependent protein kinase activity	9/2275	28/17697	0.006575	0.1747	0.1597	DAPK1/EEF2K/CAMK2D/MKNK2/PHKB/ITPKA/CAMKK2/CAMK2G/PHKA2	9
MF	GO:0019888	protein phosphatase regulator activity	19/2275	82/17697	0.007076	0.1799	0.1644	ENSA/PPP4R4/PPP1R15A/PPP2R1B/SET/CALM1/DMPK/PPP1R9B/PHACTR2/RCAN1/PPP2R5E/CALM2/ANKLE2/PPP2R5C/PPP1R14C/PPP1R7/SH3RF2/RCAN2/SHOC2	19
MF	GO:0017016	Ras GTPase binding	73/2275	429/17697	0.007092	0.1799	0.1644	TBC1D2/PLCE1/DENND5A/CORO1C/ROCK1/RAB3IL1/ARHGEF10/PAK1/RIN3/CDC42EP1/CDC42EP3/NET1/TBC1D4/MICALL1/RAB3GAP1/RABGAP1/SH3BP4/TBC1D22B/RAB11FIP2/FMNL2/FGD4/SERGEF/NPC1L1/RHOBTB3/FGD1/EHD1/DAAM2/ITPKA/OPTN/EVI5L/ARHGAP1/RABGGTA/MICAL3/RIN2/RANBP3L/ARHGEF5/EPS8/DGKI/TIAM2/ARHGEF17/SYTL4/RPH3A/DOCK4/STXBP5/ARHGEF12/RALBP1/GDI1/DIAPH1/PLEKHG4/ROCK2/RAB11FIP1/TBC1D9B/NXT1/SBF2/ARHGDIB/TRAPPC4/FARP1/TBC1D10C/RANBP17/PKN2/RIN1/TBC1D8/DVL1/DVL2/MYCBP2/BICD2/NGEF/SBF1/PLEKHG2/ANKRD27/PICALM/XPO7/RCBTB2	73
MF	GO:1901681	sulfur compound binding	46/2275	250/17697	0.007382	0.1831	0.1673	CXCL6/PTGES/CXCL10/THBS2/CCL8/CCL7/FGF2/PF4V1/PDCD5/VEGFA/BMP4/ACACB/GREM2/LANCL1/SLIT2/CXCL11/HDGF/THBS1/DBI/NAV2/PRMT1/FGFRL1/DPYSL3/HBEGF/ENPP1/LIPG/CCDC80/ITGA2/RPL22/SOAT1/CRISPLD2/ANXA4/HSD17B12/FBN1/PGF/ACBD3/RSPO2/LTBP2/FST/SCP2/FGF10/BSPH1/GNMT/ZNF146/TPMT/COL5A1	46
MF	GO:0060589	nucleoside-triphosphatase regulator activity	60/2275	344/17697	0.008215	0.1841	0.1683	TBC1D2/BAG2/ASAP3/SIPA1L1/DNAJA1/RIN3/ARHGAP18/DNAJC19/SLIT2/TBC1D4/FNIP2/ARHGAP28/RAB3GAP1/RABGAP1/RINL/FNIP1/SH3BP4/GPSM2/SIRPA/TBC1D22B/RGS2/CHN1/ERRFI1/RAB4A/DNAJC15/RGS16/STARD13/EVI5L/RGS4/ARHGAP1/RGS7/RAB3A/RIN2/SESN2/RANBP3L/FAM13B/NCAPH/DGKI/TIAM2/BRSK2/ARHGAP10/DOCK4/STXBP5/GRPEL1/ARHGEF12/GRPEL2/RALBP1/GDI1/ASAP1/ARHGAP24/ARHGAP21/TBC1D9B/TBC1D19/ARHGDIB/TBC1D10C/RIN1/TBC1D8/ARL2BP/ANKRD27/ASAP2	60
MF	GO:0004303	estradiol 17-beta-dehydrogenase activity	5/2275	11/17697	0.00825	0.1841	0.1683	RDH8/DHRS11/HSD17B12/HSD17B7/HSD17B6	5
MF	GO:0031996	thioesterase binding	5/2275	11/17697	0.00825	0.1841	0.1683	TRAF3/TRAF2/ARF6/CDC42/ADRA2A	5
MF	GO:0048407	platelet-derived growth factor binding	5/2275	11/17697	0.00825	0.1841	0.1683	PDGFRB/COL1A1/COL4A1/COL1A2/COL5A1	5
MF	GO:0052650	NADP-retinol dehydrogenase activity	5/2275	11/17697	0.00825	0.1841	0.1683	AKR1B1/RDH10/RDH8/DHRS3/RDH13	5
MF	GO:0005504	fatty acid binding	10/2275	34/17697	0.008512	0.1863	0.1702	ACOX2/PRR7/FABP3/STX3/ADH5/NDUFAB1/SCP2/PPARG/ID3/ACOXL	10
MF	GO:0070888	E-box binding	13/2275	50/17697	0.008996	0.1894	0.1731	AHR/TCF12/ARNTL/MITF/SNAI2/ASCL2/GATA3/PER1/MAX/PPARG/MYBBP1A/ARNTL2/ATOH8	13
MF	GO:0005178	integrin binding	27/2275	132/17697	0.009211	0.1894	0.1731	ICAM1/VCAM1/IL1B/S1PR3/FGF2/ISG15/PRKCA/ESM1/JAM3/LAMB1/ITGB5/VWF/THBS1/PXN/ITGB8/NISCH/ITGA2/FBN1/ACTN4/COL16A1/LGALS8/MYH9/IGF1/ICAM5/TLN1/ITGBL1/COL5A1	27
MF	GO:0005543	phospholipid binding	72/2275	427/17697	0.009217	0.1894	0.1731	CYTH3/PLD1/OSBPL10/ABCA1/PITPNC1/ATP8B1/PSD4/PLCD1/PLA2G4A/OSBPL1A/MYOF/SNX30/ESYT1/ANXA11/ZCCHC14/PLEKHF1/PLA2G4C/SNX4/WIPI1/SGIP1/THBS1/ANXA8/ANXA10/CCDC88A/MICALL1/MYO1E/GSDMD/SDCBP/VPS36/NISCH/LPAR1/PLEKHA3/AXL/ITPR2/CPNE3/WNT5A/TNFAIP8L3/ANXA4/TPCN1/WDFY1/SYT4/PFN2/OSBPL5/SH3PXD2B/APPL2/SYTL4/RPH3A/PXK/FERMT2/PLEK2/PLEKHF2/ASAP1/MPPE1/SYT1/CPS1/PIGK/WDR45/MYO10/SBF2/MITD1/GAS6/ZFYVE19/NUP35/ATP13A2/SH3YL1/TLN1/FZD7/PLEKHA4/SGK3/PICALM/SNX3/SNX10	72
MF	GO:0008138	protein tyrosine/serine/threonine phosphatase activity	12/2275	45/17697	0.009617	0.1894	0.1731	DUSP6/DUSP14/SSH1/DUSP23/CDC14B/DUSP3/DUSP12/DUSP16/DUSP18/DUSP10/DUSP5/SBF1	12
MF	GO:0048156	tau protein binding	12/2275	45/17697	0.009617	0.1894	0.1731	BAG2/ROCK1/FYN/DCTN1/MAP1A/CDK5/ACTB/BRSK2/ROCK2/MARK4/TAOK1/PICALM	12
MF	GO:0030674	protein binding, bridging	33/2275	170/17697	0.009708	0.1894	0.1731	FSCN1/DAB2/CNTNAP1/HERPUD1/IRS1/GRB14/ANK3/DDX20/SDCBP/ERCC2/MAP1A/CHN1/FLRT2/BCL3/ARRDC4/SPSB1/OPTN/ARHGAP1/SHB/BIN3/FLRT3/SOCS2/DET1/TRIM6/MMS19/COL1A2/GAS6/PTPN11/SH2B1/DVL2/BICD2/BFAR/CRKL	33
MF	GO:0043621	protein self-association	14/2275	56/17697	0.009842	0.1894	0.1731	TNFAIP3/CCL5/RSAD2/ZFYVE27/SLC2A1/GPSM2/FHOD1/NKX3-1/AGA/ZNF639/BCL10/PPARG/DVL2/ADAM8	14
MF	GO:0019211	phosphatase activator activity	6/2275	16/17697	0.01138	0.2056	0.1879	BMP2/PPP1R15A/CALM1/PPP2R5E/CALM2/PPP2R5C	6
MF	GO:0050780	dopamine receptor binding	6/2275	16/17697	0.01138	0.2056	0.1879	CLIC6/GNA13/GNA12/VPS35/DLG4/PTPN11	6
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	26/2275	128/17697	0.01144	0.2056	0.1879	BMP2/AKR1B1/CBR3/HSD11B1/RDH10/RDH8/IDH1/DHRS11/DHRS3/HADH/ADH5/CBR4/IMPDH2/HIBADH/CRYL1/HSD17B12/HSD3B7/LDHB/HSD17B7/PHGDH/ME1/BDH2/HSD17B6/LDHD/RDH13/ADH1C	26
MF	GO:0019955	cytokine binding	26/2275	128/17697	0.01144	0.2056	0.1879	KIT/IFNGR1/IFNAR1/PDPN/OSMR/TNFRSF14/TNFRSF1B/IL6ST/IL12A/IL18R1/GREM2/LRRC32/BMPR2/GBP1/ITGA4/THBS1/ZFP36/GHR/EBI3/GDF5/FZD4/IL12RB2/KLHL20/IL11RA/ENG/CCR10	26
MF	GO:0051015	actin filament binding	37/2275	198/17697	0.01188	0.2056	0.1879	PLS3/NEXN/FSCN1/ARPC1A/DBN1/CORO1C/PANX1/LIMA1/ACTR3/SHROOM3/ANXA8/MYO1E/MYOM1/DSTN/PPP1R9B/ZNF185/TPM4/ARPC2/CAPZA2/MYO18A/SHROOM2/MYOM3/GSN/CORO2A/ACTN4/FERMT2/KPTN/ABL1/SAMD14/MYO10/ACTR2/MYH6/FERMT1/MYH9/MYH10/MYO1D/TLN1	37
MF	GO:0004860	protein kinase inhibitor activity	15/2275	63/17697	0.01221	0.2056	0.1879	TRIB1/HSPB1/TRIB2/SOCS1/SOCS3/TRIB3/KAT2B/DNAJC3/HEXIM2/CDKN2C/CDKN1C/ITPRIP/GMFB/PKIG/CDKN1A	15
MF	GO:0004000	adenosine deaminase activity	5/2275	12/17697	0.01266	0.2056	0.1879	ADAR/ADA/ADARB1/ZBP1/ADAT1	5
MF	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	5/2275	12/17697	0.01266	0.2056	0.1879	KAT2B/HEXIM2/CDKN2C/CDKN1C/CDKN1A	5
MF	GO:0016004	phospholipase activator activity	5/2275	12/17697	0.01266	0.2056	0.1879	CCL5/CCL8/CCL3/ARF1/NSMAF	5
MF	GO:0030898	actin-dependent ATPase activity	5/2275	12/17697	0.01266	0.2056	0.1879	MYO10/MYH6/MYH9/MYH10/MYO1D	5
MF	GO:0019789	SUMO transferase activity	7/2275	21/17697	0.01297	0.2056	0.1879	NSMCE2/ZMIZ2/TOPORS/KIAA1586/RNF212/ZNF451/PIAS3	7
MF	GO:0019905	syntaxin binding	17/2275	75/17697	0.01306	0.2056	0.1879	ABCA1/DAPK1/STX6/RAB4A/SYPL2/SNAP47/SYT4/STXBP5/SNPH/STXBP1/SYT1/STX16/ABL1/TMED9/TMED10/VAMP7/NAPB	17
MF	GO:0019887	protein kinase regulator activity	34/2275	180/17697	0.01317	0.2056	0.1879	CCL5/CXCL10/TRIB1/HSPB1/TRIB2/DAXX/GPRC5A/SOCS1/SOCS3/CALM1/CCND1/ELP4/KIDINS220/CCNO/STK4/TRIB3/KAT2B/DNAJC3/HEXIM2/CCNG2/CDKN2C/MTCP1/CDKN1C/CCNYL1/CCNG1/CALM2/ITPRIP/GMFB/CCNJL/GAS6/PKIG/CDKN1A/MNAT1/TAOK1	34
MF	GO:0005164	tumor necrosis factor receptor binding	9/2275	31/17697	0.01345	0.2056	0.1879	CD70/TNFSF9/STAT1/TNFSF13B/TRAF3/TRIM37/FADD/TRAF2/TNF	9
MF	GO:0042605	peptide antigen binding	9/2275	31/17697	0.01345	0.2056	0.1879	TAP1/HLA-E/HLA-F/HLA-A/HLA-G/HLA-DQB1/TAPBP/HLA-B/HLA-H	9
MF	GO:0017137	Rab GTPase binding	33/2275	175/17697	0.01477	0.2227	0.2036	TBC1D2/DENND5A/RAB3IL1/RIN3/TBC1D4/MICALL1/RAB3GAP1/RABGAP1/TBC1D22B/RAB11FIP2/NPC1L1/RHOBTB3/EHD1/OPTN/EVI5L/ARHGAP1/RABGGTA/MICAL3/RIN2/SYTL4/RPH3A/STXBP5/GDI1/RAB11FIP1/TBC1D9B/SBF2/TRAPPC4/TBC1D10C/TBC1D8/BICD2/SBF1/ANKRD27/PICALM	33
MF	GO:0004857	enzyme inhibitor activity	63/2275	375/17697	0.0152	0.2243	0.205	BIRC3/SERPINA9/ENSA/SERPINB2/TRIB1/HSPB1/SERPINB8/TRIB2/RECK/BIRC2/C3/TNFAIP8/APBA3/SOCS1/SOCS3/SET/SLIT2/PPP1R12A/FNIP2/PI3/CRIM1/TRIB3/FNIP1/PPP1R9B/KAT2B/CAST/DNAJC3/PHACTR2/HEXIM2/POT1/PPP1R12C/PARP9/CDKN2C/ANXA4/COL6A3/CDKN1C/TIMP4/DGKI/SPINK6/RNH1/USP14/ITIH1/SERPINH1/SERPINB1/BIRC6/SPINK1/WFDC3/ITPRIP/GMFB/SERPINE1/HMSD/GAS6/PKIG/PPP1R14C/CDKN1A/SERPINA4/UBE2Z/SH3RF2/SERPINA3/CSTB/SERPINA1/SERPINF2/PSMF1	63
MF	GO:0008201	heparin binding	32/2275	169/17697	0.01527	0.2243	0.205	CXCL6/CXCL10/THBS2/CCL8/CCL7/FGF2/PF4V1/PDCD5/VEGFA/BMP4/GREM2/SLIT2/CXCL11/HDGF/THBS1/NAV2/FGFRL1/HBEGF/LIPG/CCDC80/RPL22/CRISPLD2/ANXA4/HSD17B12/FBN1/PGF/RSPO2/LTBP2/FGF10/BSPH1/ZNF146/COL5A1	32
MF	GO:0070628	proteasome binding	6/2275	17/17697	0.01571	0.2245	0.2051	RAD23B/RAD23A/USP14/UBD/PSME4/PSMF1	6
MF	GO:0051393	alpha-actinin binding	10/2275	37/17697	0.0158	0.2245	0.2051	PDLIM4/ADORA2A/PKD2/MYOM1/MYOM3/PDLIM5/PDLIM2/PPARG/PALLD/PDLIM3	10
MF	GO:0044389	ubiquitin-like protein ligase binding	53/2275	308/17697	0.01589	0.2245	0.2051	NFKBIA/BID/TRIB1/TRIB2/DIO2/BAG2/PPARGC1A/SQSTM1/CEBPB/UBE2L6/DAXX/TNFRSF14/PRR7/TNFRSF1B/FOXO1/GABARAPL1/STAT1/DNAJA1/RNF20/MID1/NKD2/TRAF3/VCL/RPA2/CD40/DDX58/PSMA3/TRIM37/ITCH/UBASH3B/TRIB3/PXN/MC1R/STAT2/PARP9/ARIH1/FZD8/HLTF/TRAF2/UBE2T/UBXN1/SUMO3/FZD4/NEK6/DET1/RTN4/BCL10/RALA/UBB/PER1/CDKN1A/ACTG1/ZNF675	53
MF	GO:0004674	protein serine/threonine kinase activity	72/2275	439/17697	0.01703	0.2376	0.2171	IRAK2/MAP3K8/RIPK2/ERN1/CDK6/SQSTM1/PRKCA/SIK3/DAPK1/EEF2K/ROCK1/IRAK4/PLK2/PAK1/IRAK3/PIM2/CAMK2D/BMPR2/LATS2/CCL3/NRBP2/DYRK2/PIM1/MAP3K1/MKNK2/STK4/MAPK13/EIF2AK4/STK38L/DMPK/HIPK2/ERCC2/SRPK3/PHKB/CSNK1G2/RPS6KA4/NUAK1/CSNK1E/CPNE3/ITPKA/CDK5/ARAF/CAMKK2/RIPK4/CDKL4/MYLK/MAP3K2/TLK1/BMP2K/MLKL/CAMK2G/PPM1D/BRSK2/CDK8/ICK/NEK6/PRKAB2/PRKCD/PDK3/ROCK2/MARK4/CLK4/PHKA2/MNAT1/PKN2/SIK1/CSNK1G3/TAOK1/CDK7/MAST4/DCLK2/SGK3	72
MF	GO:0015932	nucleobase-containing compound transmembrane transporter activity	11/2275	43/17697	0.01763	0.243	0.2221	SLC25A24/SLC28A3/SLC35A1/ABCD1/SLC25A33/SLC35B4/SLC35B1/SLC25A36/SLC29A1/SLC35C1/ABCC11	11
MF	GO:0034450	ubiquitin-ubiquitin ligase activity	5/2275	13/17697	0.01843	0.2449	0.2238	UBE4A/UBR5/PPIL2/UBE4B/PELI2	5
MF	GO:0042910	xenobiotic transmembrane transporter activity	5/2275	13/17697	0.01843	0.2449	0.2238	SLC2A1/ABCC1/ABCC2/ABCG2/RALBP1	5
MF	GO:0072542	protein phosphatase activator activity	5/2275	13/17697	0.01843	0.2449	0.2238	PPP1R15A/CALM1/PPP2R5E/CALM2/PPP2R5C	5
MF	GO:0015485	cholesterol binding	12/2275	49/17697	0.01902	0.2468	0.2255	OSBPL10/ABCA1/OSBPL1A/NFE2L1/SOAT1/OSBPL3/OSBPL5/STARD3NL/SCP2/OSBPL7/SULT2B1/GRAMD1A	12
MF	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	12/2275	49/17697	0.01902	0.2468	0.2255	CCND1/CCNO/KAT2B/HEXIM2/CCNG2/CDKN2C/CDKN1C/CCNYL1/CCNG1/CCNJL/CDKN1A/MNAT1	12
MF	GO:0019903	protein phosphatase binding	27/2275	140/17697	0.0195	0.2502	0.2287	ITGA1/KCNN4/ENSA/PDLIM4/FBXL2/FOXO1/STAT1/PPP1R15A/PPP1R3F/TRAF3/RPA2/PIK3R2/PXN/SIRPA/PPP1R9B/STAT6/TRAF2/STAU1/DLG4/ANKLE2/GRIN3A/PPARG/ROS1/SH3RF2/SHOC2/STAT3/SNX3	27
MF	GO:0003714	transcription corepressor activity	42/2275	238/17697	0.0199	0.2523	0.2306	RELB/MSC/CITED2/BASP1/RCOR3/DAXX/WWTR1/SAP30/NR2F2/CCND1/ZHX1/HDGF/BEND6/LMCD1/WTIP/RCOR2/JAZF1/ZNF653/TRIB3/ZNF281/DR1/HIPK2/YAP1/BATF3/PARP9/TBL1Y/CDYL2/SIRT1/JUNB/E2F6/NCOR2/DRAP1/ID3/OLIG3/TLE1/PARP15/SIN3B/ZHX3/TBL1XR1/MYBBP1A/ZNF451/SIRT6	42
MF	GO:0070064	proline-rich region binding	6/2275	18/17697	0.02106	0.2614	0.2389	CCND1/CYLD/GHR/YAP1/ABL1/NEDD4	6
MF	GO:0019210	kinase inhibitor activity	15/2275	67/17697	0.02115	0.2614	0.2389	TRIB1/HSPB1/TRIB2/SOCS1/SOCS3/TRIB3/KAT2B/DNAJC3/HEXIM2/CDKN2C/CDKN1C/ITPRIP/GMFB/PKIG/CDKN1A	15
MF	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	8/2275	28/17697	0.02132	0.2614	0.2389	WIPI1/TPCN1/SH3PXD2B/PLEK2/WDR45/ATP13A2/PLEKHA4/SNX3	8
MF	GO:0031406	carboxylic acid binding	35/2275	193/17697	0.02164	0.2626	0.24	TNFAIP6/DDAH1/ACOX2/PRR7/PYGL/SESN1/ACACB/CYP27C1/CD44/FABP3/RXRA/NR2F2/VCAN/STX3/P4HA2/GLUD1/EGLN1/ADH5/SESN3/UBR1/PLOD2/IGF2R/VDR/NDUFAB1/SESN2/ASS1/DDAH2/CPS1/GRIN3A/SCP2/PPARG/SLC19A1/ID3/GNMT/ACOXL	35
MF	GO:0000149	SNARE binding	22/2275	110/17697	0.02233	0.2679	0.2449	TNFAIP2/ABCA1/DAPK1/STX3/STX6/RAB4A/SYPL2/SNAP47/SYT4/STXBP5/SNPH/STXBP1/SYT1/STX16/ABL1/TMED9/TMED10/VAMP7/TSNARE1/NAPB/ANKRD27/PICALM	22
MF	GO:0004721	phosphoprotein phosphatase activity	33/2275	182/17697	0.02521	0.2899	0.2649	PPP3CC/PTPRE/DUSP6/PPP2R1B/DUSP14/CDC25A/SSH1/UBASH3B/PTPN13/DUSP23/CDC14B/PPP4C/DUSP3/UBLCP1/CAMK2G/PPM1D/PPM1M/PTPRM/DUSP12/DUSP16/PPP3CA/DUSP18/CTDSPL2/DUSP10/PDXP/CTDSP2/PTPN11/MYH6/DUSP5/SHOC2/LRRC30/SBF1/EYA2	33
MF	GO:0061135	endopeptidase regulator activity	33/2275	182/17697	0.02521	0.2899	0.2649	BIRC3/PSME2/SERPINA9/SERPINB2/SERPINB8/RECK/BIRC2/PSME1/C3/TNFAIP8/PI3/CRIM1/CAST/COL6A3/TIMP4/SPINK6/USP14/ITIH1/SERPINH1/SERPINB1/BIRC6/SPINK1/WFDC3/SERPINE1/HMSD/GAS6/SERPINA4/UBE2Z/SERPINA3/CSTB/SERPINA1/SERPINF2/PSMF1	33
MF	GO:0036041	long-chain fatty acid binding	5/2275	14/17697	0.0257	0.2899	0.2649	PRR7/FABP3/STX3/SCP2/PPARG	5
MF	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity	5/2275	14/17697	0.0257	0.2899	0.2649	SOCS1/SOCS3/PIK3R2/PIK3R3/SOCS2	5
MF	GO:0060229	lipase activator activity	5/2275	14/17697	0.0257	0.2899	0.2649	CCL5/CCL8/CCL3/ARF1/NSMAF	5
MF	GO:0003743	translation initiation factor activity	12/2275	51/17697	0.02572	0.2899	0.2649	EIF4A2/DENR/EIF4G3/EIF1/EIF4A1/DHX29/EIF3E/MTIF3/EIF2B5/EIF2B4/EIF2S2/EIF1B	12
MF	GO:0008083	growth factor activity	30/2275	163/17697	0.02636	0.2942	0.2689	CXCL1/BMP2/IL6/CSF2/LIF/OSGIN2/CSF1/FGF2/TYMP/VEGFA/EREG/BMP4/IL12A/HDGF/TGFA/INHBB/HBEGF/PDGFD/TGFB2/CLCF1/GDF5/GDF15/PGF/FGF5/PDGFC/GMFB/FGF10/GDF6/IGF1/TFF1	30
MF	GO:0098641	cadherin binding involved in cell-cell adhesion	6/2275	19/17697	0.02751	0.3029	0.2768	CDC42EP1/TRIM29/S100A11/CNN3/PDLIM5/TACSTD2	6
MF	GO:0050662	coenzyme binding	49/2275	291/17697	0.02828	0.3029	0.2768	CBR3/ACOX2/GPD1L/KYNU/PYGL/ALDH1A3/ACACB/GMDS/IDH1/GCH1/DBI/P4HA2/ACAT1/GLUD1/PRMT1/EGLN1/HADH/SRD5A1/CYB5R2/TM7SF2/CRYZ/PNPO/CBR4/AADAT/PLOD2/SOAT1/NOX5/SIRT1/HIBADH/CRYL1/MICAL3/ABAT/FMO5/LDHB/ALAS1/ACBD3/PHGDH/ME1/BDH2/LDHD/SCP2/NUDT6/PARP15/GNMT/FMO4/ACOXL/TPMT/ACADM/SIRT6	49
MF	GO:0032813	tumor necrosis factor receptor superfamily binding	11/2275	46/17697	0.02857	0.3029	0.2768	BID/CD70/TNFSF9/STAT1/CFLAR/TNFSF13B/TRAF3/TRIM37/FADD/TRAF2/TNF	11
MF	GO:0042805	actinin binding	11/2275	46/17697	0.02857	0.3029	0.2768	NFKB1/PDLIM4/ADORA2A/PKD2/MYOM1/MYOM3/PDLIM5/PDLIM2/PPARG/PALLD/PDLIM3	11
MF	GO:0042578	phosphoric ester hydrolase activity	60/2275	367/17697	0.02897	0.3029	0.2768	CCL5/PPP3CC/PLD1/BDKRB2/PLCD3/GDPD5/LPIN1/PLCE1/PLCD1/PDE1C/PTPRE/DUSP6/PSPH/PPP2R1B/DUSP14/FICD/PDE4D/PDE1A/CDC25A/SSH1/UBASH3B/PTPN13/DUSP23/NT5C2/ENPP1/CDC14B/NT5DC3/IMPA2/PPP4C/DUSP3/PLCB4/UBLCP1/CAMK2G/PPM1D/PPM1M/PTPRM/DUSP12/DUSP16/MPPE1/INPP5B/PPP3CA/MPPED2/DUSP18/CTDSPL2/PDE4B/DUSP10/PDXP/PDE3B/CTDSP2/PTPN11/MYH6/DUSP5/INPP1/PDE5A/SHOC2/LRRC30/SBF1/NT5DC1/EYA2/PLD3	60
MF	GO:0004867	serine-type endopeptidase inhibitor activity	19/2275	94/17697	0.02904	0.3029	0.2768	SERPINA9/SERPINB2/SERPINB8/RECK/PI3/CRIM1/COL6A3/SPINK6/ITIH1/SERPINH1/SERPINB1/SPINK1/WFDC3/SERPINE1/HMSD/SERPINA4/SERPINA3/SERPINA1/SERPINF2	19
MF	GO:0008081	phosphoric diester hydrolase activity	19/2275	94/17697	0.02904	0.3029	0.2768	CCL5/PLD1/BDKRB2/PLCD3/GDPD5/PLCE1/PLCD1/PDE1C/FICD/PDE4D/PDE1A/ENPP1/PLCB4/MPPE1/MPPED2/PDE4B/PDE3B/PDE5A/PLD3	19
MF	GO:0005548	phospholipid transporter activity	12/2275	52/17697	0.02965	0.3035	0.2774	OSBPL10/ABCA1/PITPNC1/ATP8B1/PLSCR1/PLEKHA3/TNFAIP8L3/OSBPL5/ATP8A2/PLSCR2/TMEM30B/STARD7	12
MF	GO:0050661	NADP binding	12/2275	52/17697	0.02965	0.3035	0.2774	CBR3/GMDS/IDH1/SRD5A1/TM7SF2/CRYZ/CBR4/NOX5/HIBADH/FMO5/ME1/FMO4	12
MF	GO:0015651	quaternary ammonium group transmembrane transporter activity	4/2275	10/17697	0.03012	0.3056	0.2793	SLC22A1/SLC22A4/SLC25A20/SLC22A3	4
MF	GO:0043177	organic acid binding	36/2275	205/17697	0.0313	0.3147	0.2876	TNFAIP6/DDAH1/ACOX2/PRR7/PYGL/SESN1/ACACB/CYP27C1/CD44/FABP3/RXRA/NR2F2/VCAN/STX3/P4HA2/GLUD1/EGLN1/ADH5/SESN3/UBR1/PLOD2/IGF2R/VDR/NDUFAB1/SESN2/ASS1/DDAH2/CPS1/GRIN3A/HBB/SCP2/PPARG/SLC19A1/ID3/GNMT/ACOXL	36
MF	GO:0016763	transferase activity, transferring pentosyl groups	11/2275	47/17697	0.03311	0.3259	0.2979	NAMPT/PARP12/PARP14/TYMP/GXYLT1/QTRT1/PARP9/MTAP/PARP11/PARP15/SIRT6	11
MF	GO:0042887	amide transmembrane transporter activity	11/2275	47/17697	0.03311	0.3259	0.2979	TAP1/TAP2/SLC15A3/AQP9/SEC61G/AQP7/ABCC1/ABCD1/SLC19A1/TAPBP/TIMM17B	11
MF	GO:0048018	receptor ligand activity	76/2275	482/17697	0.03349	0.3259	0.2979	CXCL1/CXCL2/CXCL6/CCL20/BMP2/NAMPT/CCL5/IL6/IL32/CXCL5/CD70/CSF2/IL1B/LIF/CXCL10/IL33/CCL2/CCL8/NDP/IL1A/OSGIN2/CSF1/CCL7/TNFSF9/FGF2/PF4V1/TYMP/VEGFA/EREG/GIP/BMP4/TNFSF13B/IL12A/CCL3L3/GREM2/CXCL3/IL26/CXCL11/CCL3/HDGF/IL15/EDN1/PTHLH/CXCL9/TGFA/INHBB/HBEGF/ADM2/SEMA4D/PDGFD/CCL1/TGFB2/EBI3/CLCF1/GDF5/FLRT2/FNDC5/WNT5A/GDF15/FBN1/TNF/PGF/FLRT3/FGF5/PDGFC/IAPP/GMFB/GAS6/NPPA/FGF10/TNFRSF11B/GDF6/SEMA4F/IGF1/CMTM8/TFF1	76
MF	GO:0098631	cell adhesion mediator activity	13/2275	59/17697	0.03442	0.3259	0.2979	ITGA1/NEXN/CDC42EP1/TRIM29/SIRPA/ITGA2/S100A11/CNN3/ITGA11/PDLIM5/TACSTD2/NPTN/PALLD	13
MF	GO:0005092	GDP-dissociation inhibitor activity	5/2275	15/17697	0.03456	0.3259	0.2979	SH3BP4/GPSM2/SESN2/GDI1/ARHGDIB	5
MF	GO:0005161	platelet-derived growth factor receptor binding	5/2275	15/17697	0.03456	0.3259	0.2979	ERN1/VEGFA/PDGFRB/PDGFD/PDGFC	5
MF	GO:0004745	retinol dehydrogenase activity	6/2275	20/17697	0.03514	0.3259	0.2979	BMP2/RDH10/RDH8/DHRS3/HSD17B6/ADH1C	6
MF	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	6/2275	20/17697	0.03514	0.3259	0.2979	VCAM1/LOXL4/IL4I1/GLUD1/PNPO/LOXL1	6
MF	GO:0016922	nuclear receptor binding	6/2275	20/17697	0.03514	0.3259	0.2979	PPARGC1A/RXRA/SLC30A9/ARID1A/SMARCE1/TADA3	6
MF	GO:0004896	cytokine receptor activity	19/2275	96/17697	0.03534	0.3259	0.2979	IFNAR2/IFNGR1/IFNAR1/IL7R/OSMR/IFNGR2/IL6ST/IL18R1/IL4R/CMKLR1/CD44/IL15RA/IL17RB/GHR/EBI3/FZD4/IL12RB2/IL11RA/CCR10	19
MF	GO:0004866	endopeptidase inhibitor activity	31/2275	175/17697	0.03892	0.3561	0.3254	BIRC3/SERPINA9/SERPINB2/SERPINB8/RECK/BIRC2/C3/TNFAIP8/PI3/CRIM1/CAST/COL6A3/TIMP4/SPINK6/USP14/ITIH1/SERPINH1/SERPINB1/BIRC6/SPINK1/WFDC3/SERPINE1/HMSD/GAS6/SERPINA4/UBE2Z/SERPINA3/CSTB/SERPINA1/SERPINF2/PSMF1	31
MF	GO:0005539	glycosaminoglycan binding	39/2275	229/17697	0.03967	0.3561	0.3255	CXCL6/TNFAIP6/CXCL10/THBS2/CCL8/CCL7/FGF2/PF4V1/PDCD5/VEGFA/BMP4/GREM2/CD44/SLIT2/VCAN/CXCL11/HDGF/THBS1/NAV2/SULF2/FGFRL1/DPYSL3/HBEGF/LIPG/CCDC80/RPL22/CRISPLD2/ANXA4/SULF1/HSD17B12/FBN1/PGF/RSPO2/LTBP2/ENG/FGF10/BSPH1/ZNF146/COL5A1	39
MF	GO:0043178	alcohol binding	17/2275	85/17697	0.04101	0.3561	0.3255	OSBPL10/ABCA1/XPR1/OSBPL1A/CYP27C1/NFE2L1/TRPC1/SOAT1/ITPR2/OSBPL3/OSBPL5/RPH3A/STARD3NL/SCP2/OSBPL7/SULT2B1/GRAMD1A	17
MF	GO:0016790	thiolester hydrolase activity	9/2275	37/17697	0.04105	0.3561	0.3255	PNKD/HIBCH/NUDT7/PPT1/HAGH/ACAA2/ESD/UFSP2/ACOT8	9
MF	GO:0017147	Wnt-protein binding	9/2275	37/17697	0.04105	0.3561	0.3255	RECK/FZD1/ROR1/FZD2/LRP5/AXL/FZD8/FZD4/FZD7	9
MF	GO:0004435	phosphatidylinositol phospholipase C activity	7/2275	26/17697	0.04141	0.3561	0.3255	CCL5/BDKRB2/PLCD3/GDPD5/PLCE1/PLCD1/PLCB4	7
MF	GO:0017075	syntaxin-1 binding	7/2275	26/17697	0.04141	0.3561	0.3255	DAPK1/SYPL2/SYT4/STXBP5/SNPH/STXBP1/SYT1	7
MF	GO:0051019	mitogen-activated protein kinase binding	7/2275	26/17697	0.04141	0.3561	0.3255	TNIP1/GCH1/PRMT1/SIRT1/PPM1D/ABL1/DUSP10	7
MF	GO:0004312	fatty acid synthase activity	4/2275	11/17697	0.04262	0.3561	0.3255	ELOVL5/ELOVL7/ELOVL2/ELOVL3	4
MF	GO:0036122	BMP binding	4/2275	11/17697	0.04262	0.3561	0.3255	GREM2/BMPR2/GDF5/ENG	4
MF	GO:0045236	CXCR chemokine receptor binding	4/2275	11/17697	0.04262	0.3561	0.3255	CXCL10/CXCL11/ITCH/CXCL9	4
MF	GO:0089720	caspase binding	4/2275	11/17697	0.04262	0.3561	0.3255	RIPK2/FADD/MAGEA3/BFAR	4
MF	GO:0048020	CCR chemokine receptor binding	10/2275	43/17697	0.04276	0.3561	0.3255	CCL20/CCL5/CCL2/CCL8/CCL7/STAT1/CCL3L3/CCL3/CCL1/STAT3	10
MF	GO:0005518	collagen binding	14/2275	67/17697	0.04347	0.3579	0.3271	ITGA1/C1QTNF1/PAK1/CTSS/CD44/VWF/THBS1/ITGA2/MMP9/NID2/ITGA11/HSD17B12/SPARC/SERPINH1	14
MF	GO:0008483	transaminase activity	6/2275	21/17697	0.04401	0.3579	0.3271	GFPT2/PSAT1/AADAT/AMT/ABAT/BCAT2	6
MF	GO:0050750	low-density lipoprotein particle receptor binding	6/2275	21/17697	0.04401	0.3579	0.3271	DNAJA1/LANCL1/HSPG2/CLTC/SYT1/PICALM	6
MF	GO:0005159	insulin-like growth factor receptor binding	5/2275	16/17697	0.0451	0.3579	0.3271	SOCS1/IRS1/YWHAH/SOCS2/IGF1	5
MF	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	5/2275	16/17697	0.0451	0.3579	0.3271	VCAM1/LOXL4/IL4I1/PNPO/LOXL1	5
MF	GO:0030280	structural constituent of epidermis	5/2275	16/17697	0.0451	0.3579	0.3271	KRTAP1-3/PI3/KRT82/KRT2/FLG	5
MF	GO:0030165	PDZ domain binding	17/2275	86/17697	0.04522	0.3579	0.3271	LNX1/SLC22A4/FZD1/CRIM1/KIDINS220/FZD2/SDC2/LPAR1/FZD8/FZD4/DLG4/DOCK4/SNTA1/MUC17/SNTB1/LIN7C/FZD7	17
MF	GO:0042056	chemoattractant activity	9/2275	38/17697	0.04788	0.3763	0.3439	CCL5/CXCL10/FGF2/VEGFA/BMP4/CCL3/WNT5A/PGF/FGF10	9
MF	GO:0019902	phosphatase binding	32/2275	185/17697	0.04835	0.3773	0.3449	ITGA1/KCNN4/ENSA/PDLIM4/FBXL2/FOXO1/STAT1/PPP1R15A/PPP1R3F/TRAF3/RPA2/PIK3R2/PXN/SIRPA/PPP1R9B/STAT6/SIGLEC10/TRAF2/STAU1/DLG4/PVRIG/ANKLE2/GRIN3A/SBF2/ELL/PPARG/ROS1/SH3RF2/SH3YL1/SHOC2/STAT3/SNX3	32
MF	GO:0061134	peptidase regulator activity	37/2275	219/17697	0.04884	0.3785	0.3459	BIRC3/PSME2/SERPINA9/SERPINB2/SERPINB8/RECK/BIRC2/PSME1/C3/TNFAIP8/CFLAR/PI3/CRIM1/CAST/NKX3-1/COL6A3/TIMP4/SPINK6/USP14/ITIH1/SERPINH1/SERPINB1/BIRC6/SPINK1/WFDC3/SERPINE1/HMSD/GAS6/SERPINA4/PSME4/UBE2Z/SERPINA3/CSTB/SERPINA1/SERPINF2/PSMF1/ST20	37
MF	GO:0032934	sterol binding	12/2275	56/17697	0.04971	0.379	0.3464	OSBPL10/ABCA1/OSBPL1A/NFE2L1/SOAT1/OSBPL3/OSBPL5/STARD3NL/SCP2/OSBPL7/SULT2B1/GRAMD1A	12
MF	GO:0001968	fibronectin binding	7/2275	27/17697	0.04992	0.379	0.3464	VEGFA/CTSS/ITGA4/THBS1/CCDC80/HSD17B12/SDC4	7
MF	GO:0046875	ephrin receptor binding	7/2275	27/17697	0.04992	0.379	0.3464	SIPA1L1/FYN/CHN1/EFNB1/CDK5/ABL1/ANKS1A	7
MF	GO:0000287	magnesium ion binding	36/2275	213/17697	0.05116	0.3857	0.3526	MAP3K8/ERN1/PRPS1/ATP8B1/SIK3/PSPH/IRAK4/PRPS1L1/ENO2/IRAK3/IDH1/DYRK2/NUDT18/NUDT7/STK4/STK38L/MTHFD2/RPS6KA4/GEM/ADPRHL2/ARF1/PGM3/BRSK2/ICK/ATP8A2/NEK6/FEN1/PRTFDC1/ABL1/FARSB/ENOSF1/PDXP/SUCLA2/SIK1/MAST4/EYA2	36
MF	GO:0000146	microfilament motor activity	6/2275	22/17697	0.05415	0.4002	0.3658	MYO1E/MYO10/MYH6/MYH9/MYH10/MYO1D	6
MF	GO:0003950	NAD+ ADP-ribosyltransferase activity	6/2275	22/17697	0.05415	0.4002	0.3658	PARP12/PARP14/PARP9/PARP11/PARP15/SIRT6	6
MF	GO:0017025	TBP-class protein binding	6/2275	22/17697	0.05415	0.4002	0.3658	AHR/CAND2/DR1/CAND1/THRA/YEATS2	6
MF	GO:0008022	protein C-terminus binding	32/2275	187/17697	0.05473	0.4016	0.367	DAB2/HSPB7/HSPG2/GPSM2/VPS36/ERCC2/YAP1/KPNA3/CNRIP1/CEP250/SIRT1/OPTN/PABPC1/RAB3A/TAF13/XRCC4/CACNA1B/DYNLL1/DLG4/SYT1/PEX1/ABL1/BCL10/MPDZ/ITGB3BP/KSR1/PPARG/PEX26/CDK7/HIC2/MID1IP1/PIAS3	32
MF	GO:0005109	frizzled binding	9/2275	39/17697	0.05542	0.4016	0.367	NDP/FZD1/SDCBP/WNT5B/WNT5A/RSPO2/DVL1/DVL2/FZD7	9
MF	GO:0032266	phosphatidylinositol-3-phosphate binding	9/2275	39/17697	0.05542	0.4016	0.367	PLEKHF1/WIPI1/VPS36/SH3PXD2B/PLEK2/WDR45/ZFYVE19/PLEKHA4/SNX3	9
MF	GO:0043024	ribosomal small subunit binding	5/2275	17/17697	0.05734	0.4094	0.3742	PIM1/EIF1/DHX29/MTIF3/EIF1B	5
MF	GO:0005496	steroid binding	18/2275	95/17697	0.05753	0.4094	0.3742	OSBPL10/ABCA1/HSD11B1/PGRMC2/OSBPL1A/IRX5/PAQR9/NFE2L1/SOAT1/VDR/OSBPL3/SHBG/OSBPL5/STARD3NL/SCP2/OSBPL7/SULT2B1/GRAMD1A	18
MF	GO:0004126	cytidine deaminase activity	4/2275	12/17697	0.05759	0.4094	0.3742	APOBEC3G/APOBEC3H/CDADC1/APOBEC3F	4
MF	GO:0004629	phospholipase C activity	7/2275	28/17697	0.05945	0.4199	0.3838	CCL5/BDKRB2/PLCD3/GDPD5/PLCE1/PLCD1/PLCB4	7
MF	GO:0030414	peptidase inhibitor activity	31/2275	182/17697	0.06093	0.4277	0.3909	BIRC3/SERPINA9/SERPINB2/SERPINB8/RECK/BIRC2/C3/TNFAIP8/PI3/CRIM1/CAST/COL6A3/TIMP4/SPINK6/USP14/ITIH1/SERPINH1/SERPINB1/BIRC6/SPINK1/WFDC3/SERPINE1/HMSD/GAS6/SERPINA4/UBE2Z/SERPINA3/CSTB/SERPINA1/SERPINF2/PSMF1	31
MF	GO:0051219	phosphoprotein binding	16/2275	83/17697	0.06184	0.4313	0.3942	MID1/TBL2/SOCS3/IRS1/PKD2/UBASH3B/PIK3R2/PIK3R3/IGF2R/LRP11/SHB/ABL1/PTPN11/CBLB/NEDD4/CRKL	16
MF	GO:0032182	ubiquitin-like protein binding	18/2275	96/17697	0.06265	0.4343	0.3969	TNFAIP3/HSPB1/SQSTM1/UBE2L6/BIRC2/DAXX/TP53INP2/RAD23B/UBR5/VPS36/SERBP1/DCUN1D4/RAD23A/RNF4/UBXN1/RBCK1/MARK4/NEDD4	18
MF	GO:0001784	phosphotyrosine residue binding	9/2275	40/17697	0.06368	0.4387	0.401	SOCS3/IRS1/PIK3R2/PIK3R3/SHB/ABL1/PTPN11/CBLB/CRKL	9
MF	GO:0016769	transferase activity, transferring nitrogenous groups	6/2275	23/17697	0.0656	0.4491	0.4105	GFPT2/PSAT1/AADAT/AMT/ABAT/BCAT2	6
MF	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity	22/2275	123/17697	0.0667	0.4512	0.4123	TAP1/TAP2/ABCA1/ATP6V1E2/ATP6V0B/SEC61G/ATP6V0E2/PCYOX1/ABCA5/ABCC1/ABCB10/ABCD1/ABCC2/ABCG2/ATP2A2/RALBP1/ATP1A4/TAPBP/ATP13A2/ATP6V1E1/TIMM17B/ABCC11	22
MF	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	22/2275	123/17697	0.0667	0.4512	0.4123	DDAH1/GLS/MTHFD2L/APOBEC3G/SAP30/ADAR/AMPD3/GCH1/ADA/APOBEC3H/MTHFD2/SIRT1/CDADC1/DDAH2/AGA/ADARB1/APOBEC3F/ZBP1/ADAT1/SIN3B/FAAH2/SIRT6	22
MF	GO:0019838	growth factor binding	24/2275	137/17697	0.06998	0.468	0.4277	OSMR/ESM1/IL6ST/NKD2/PDGFRB/COL1A1/LRRC32/SORT1/BMPR2/THBS1/CRIM1/RHBDF2/FGFRL1/GHR/IGF2R/API5/IGFBPL1/IL11RA/LTBP2/COL4A1/COL1A2/ENG/ITGA6/COL5A1	24
MF	GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	7/2275	29/17697	0.07003	0.468	0.4277	HSD11B1/RDH8/DHRS11/HSD17B12/HSD3B7/HSD17B7/HSD17B6	7
MF	GO:0005544	calcium-dependent phospholipid binding	11/2275	53/17697	0.07125	0.4733	0.4326	PLA2G4A/ESYT1/ANXA11/PLA2G4C/ANXA8/ANXA10/CPNE3/ANXA4/SYT4/RPH3A/SYT1	11
MF	GO:0016229	steroid dehydrogenase activity	8/2275	35/17697	0.07211	0.4734	0.4327	HSD11B1/RDH8/DHRS11/SRD5A1/HSD17B12/HSD3B7/HSD17B7/HSD17B6	8
MF	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	8/2275	35/17697	0.07211	0.4734	0.4327	AKR1B1/ALDH1A3/ADH5/ALDH7A1/PDHB/ALDH5A1/FAR1/ALDH1L2	8
MF	GO:0008179	adenylate cyclase binding	4/2275	13/17697	0.075	0.4838	0.4422	CALM1/AKAP12/CALM2/CAP2	4
MF	GO:0031434	mitogen-activated protein kinase kinase binding	4/2275	13/17697	0.075	0.4838	0.4422	TRIB1/TRIB2/TRIB3/KSR1	4
MF	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	67/2275	439/17697	0.07544	0.4838	0.4422	MAFF/NFKB1/NFKB2/IRF1/STAT4/CEBPD/ARNT2/PITX1/CEBPB/MEIS1/MAFB/NFIA/SIX1/PLSCR1/EPAS1/STAT1/MYB/DBP/TCF12/MYBL1/POU2F2/HOXC13/ETS1/EBF1/NFE2L1/KLF4/NEUROG3/MAFG/HOXA10/E2F2/ARNTL/STAT2/KLF13/MITF/STAT6/MEOX2/SIX4/HLTF/MEF2C/ATF1/FLI1/SIRT1/JUNB/ONECUT3/IRF2BP2/TP63/FOXJ2/ARID3A/HOXD3/ETV1/SALL2/ELF3/TFE3/SUB1/DLX3/CEBPA/GATA3/HOXB7/RFX5/ZNF639/NUCKS1/TFDP1/STAT3/FOXO4/AKNA/TBX3/NFIB	67
MF	GO:0030695	GTPase regulator activity	48/2275	304/17697	0.07563	0.4838	0.4422	TBC1D2/ASAP3/SIPA1L1/RIN3/ARHGAP18/SLIT2/TBC1D4/ARHGAP28/RAB3GAP1/RABGAP1/RINL/SH3BP4/GPSM2/SIRPA/TBC1D22B/RGS2/CHN1/ERRFI1/RGS16/STARD13/EVI5L/RGS4/ARHGAP1/RGS7/RIN2/SESN2/RANBP3L/FAM13B/DGKI/TIAM2/ARHGAP10/DOCK4/STXBP5/ARHGEF12/RALBP1/GDI1/ASAP1/ARHGAP24/ARHGAP21/TBC1D9B/TBC1D19/ARHGDIB/TBC1D10C/RIN1/TBC1D8/ARL2BP/ANKRD27/ASAP2	48
MF	GO:0031625	ubiquitin protein ligase binding	46/2275	290/17697	0.07587	0.4838	0.4422	NFKBIA/BID/TRIB1/TRIB2/DIO2/BAG2/PPARGC1A/SQSTM1/UBE2L6/DAXX/TNFRSF14/TNFRSF1B/FOXO1/GABARAPL1/DNAJA1/RNF20/MID1/NKD2/TRAF3/VCL/RPA2/CD40/DDX58/PSMA3/TRIM37/UBASH3B/TRIB3/PXN/MC1R/ARIH1/FZD8/HLTF/TRAF2/UBE2T/UBXN1/FZD4/NEK6/DET1/RTN4/BCL10/RALA/UBB/PER1/CDKN1A/ACTG1/ZNF675	46
MF	GO:0015399	primary active transmembrane transporter activity	22/2275	125/17697	0.07687	0.4854	0.4437	TAP1/TAP2/ABCA1/ATP6V1E2/ATP6V0B/SEC61G/ATP6V0E2/PCYOX1/ABCA5/ABCC1/ABCB10/ABCD1/ABCC2/ABCG2/ATP2A2/RALBP1/ATP1A4/TAPBP/ATP13A2/ATP6V1E1/TIMM17B/ABCC11	22
MF	GO:0035258	steroid hormone receptor binding	17/2275	92/17697	0.07705	0.4854	0.4437	PPARGC1A/CEBPB/DAXX/RERG/WIPI1/RNF14/FHL2/NKX3-1/DDX5/RNF4/YWHAH/MMS19/NCOR2/PPARG/STAT3/CDK7/NCOA6	17
MF	GO:0001965	G-protein alpha-subunit binding	6/2275	24/17697	0.07835	0.4854	0.4437	GPSM2/F2R/RGS2/LPAR1/IGF2R/RGS4	6
MF	GO:0072509	divalent inorganic cation transmembrane transporter activity	6/2275	24/17697	0.07835	0.4854	0.4437	SLC39A14/SLC11A2/SLC41A2/SLC39A10/SLC39A8/SLC30A1	6
MF	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	27/2275	159/17697	0.07835	0.4854	0.4437	CYP4B1/PTGS2/CH25H/CYP27C1/FTO/CYP2U1/SCD/P4HA2/CYP20A1/TET1/EGLN1/CYP27B1/MOXD1/CYP1A2/PLOD2/MICAL3/FMO5/HMOX2/TET3/ALKBH8/HSPBAP1/PTGS1/FMO4/CYP2C19/CYP2S1/CYP19A1/CYP4X1	27
MF	GO:0005085	guanyl-nucleotide exchange factor activity	35/2275	214/17697	0.07873	0.4854	0.4437	CYTH3/PSD4/PLCE1/DENND5A/RAB3IL1/ARHGEF10/RIN3/BCAR3/IQSEC1/NET1/RAB3GAP1/RINL/FNIP1/FGD4/SERGEF/FGD1/RIN2/ARHGEF5/EPS8/TIAM2/ARHGEF17/EIF2B5/DOCK4/EIF2B4/ARHGEF12/PLEKHG4/SBF2/TRAPPC4/FARP1/MYCBP2/NGEF/SBF1/PLEKHG2/ANKRD27/RCBTB2	35
MF	GO:0043394	proteoglycan binding	8/2275	36/17697	0.08274	0.5021	0.4589	CTSS/SLIT2/THBS1/SDCBP/ITGA2/TNC/FST/COL5A1	8
MF	GO:0046915	transition metal ion transmembrane transporter activity	8/2275	36/17697	0.08274	0.5021	0.4589	SLC39A14/SLC11A2/SLC25A28/SLC25A37/SLC39A10/SLC39A8/SLC30A1/MCOLN1	8
MF	GO:0030374	nuclear receptor transcription coactivator activity	13/2275	67/17697	0.08278	0.5021	0.4589	PPARGC1A/NCOA7/FGF2/SLC30A9/THRA/CARM1/VDR/ZMIZ2/RNF4/ACTN4/PPARG/TADA3/NCOA6	13
MF	GO:0051117	ATPase binding	15/2275	80/17697	0.08383	0.5057	0.4622	ABCA1/NKD2/PDE4D/PKD2/RDX/RAB4A/RAB3A/UBXN1/BRSK2/SNTA1/RALA/PEX26/UBE4B/ATP6V1E1/SNX10	15
MF	GO:0004725	protein tyrosine phosphatase activity	18/2275	100/17697	0.08623	0.5106	0.4667	PTPRE/DUSP6/DUSP14/CDC25A/SSH1/UBASH3B/PTPN13/DUSP23/CDC14B/DUSP3/PTPRM/DUSP12/DUSP16/DUSP18/DUSP10/PTPN11/DUSP5/EYA2	18
MF	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	5/2275	19/17697	0.08694	0.5106	0.4667	GALNT10/GALNT5/GALNT4/GALNT11/GALNT1	5
MF	GO:0015215	nucleotide transmembrane transporter activity	5/2275	19/17697	0.08694	0.5106	0.4667	SLC25A24/ABCD1/SLC25A33/SLC25A36/ABCC11	5
MF	GO:0016722	oxidoreductase activity, oxidizing metal ions	5/2275	19/17697	0.08694	0.5106	0.4667	FTH1/CYBRD1/CYB561/FTHL17/STEAP2	5
MF	GO:0031690	adrenergic receptor binding	5/2275	19/17697	0.08694	0.5106	0.4667	PDE4D/ARRDC3/DLG4/NEDD4/ADRA2A	5
MF	GO:0001671	ATPase activator activity	6/2275	25/17697	0.09238	0.5338	0.4879	DNAJA1/DNAJC19/RAB4A/DNAJC15/RAB3A/NCAPH	6
MF	GO:0005104	fibroblast growth factor receptor binding	6/2275	25/17697	0.09238	0.5338	0.4879	FGF2/FLRT2/FLRT3/FGF5/NPTN/FGF10	6
MF	GO:0035586	purinergic receptor activity	6/2275	25/17697	0.09238	0.5338	0.4879	ADORA2A/P2RY11/ADORA1/P2RX3/P2RX7/ADORA3	6
MF	GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	9/2275	43/17697	0.09296	0.5338	0.4879	AKR1B1/ALDH1A3/BCKDHB/ADH5/ALDH7A1/PDHB/ALDH5A1/FAR1/ALDH1L2	9
MF	GO:0005484	SNAP receptor activity	7/2275	31/17697	0.09432	0.5338	0.4879	BET1/STX3/STX6/SNAP47/STX16/VAMP7/TSNARE1	7
MF	GO:0015248	sterol transporter activity	7/2275	31/17697	0.09432	0.5338	0.4879	OSBPL10/ABCA1/OSBPL1A/OSBPL3/OSBPL5/OSBPL7/GRAMD1A	7
MF	GO:0005338	nucleotide-sugar transmembrane transporter activity	4/2275	14/17697	0.09472	0.5338	0.4879	SLC35A1/SLC35B4/SLC35B1/SLC35C1	4
MF	GO:0070330	aromatase activity	4/2275	14/17697	0.09472	0.5338	0.4879	CYP4B1/CYP2U1/CYP19A1/CYP4X1	4
MF	GO:0020037	heme binding	23/2275	135/17697	0.09533	0.5338	0.4879	CYP4B1/PTGS2/IDO1/CYP27C1/CYP2U1/CYBA/CYP20A1/FLVCR2/CYP27B1/CYP1A2/CYB5A/CYGB/NOX5/HMOX2/CYB5B/SDHD/NGB/HBB/PTGS1/CYP2C19/CYP2S1/CYP19A1/CYP4X1	23
MF	GO:0001883	purine nucleoside binding	58/2275	381/17697	0.09567	0.5338	0.4879	MX1/TUBB3/RAB23/EHD4/IFI44L/MX2/DIRAS1/GBP2/DAPK1/RAB9A/RAB13/GBP5/RERG/RRAD/RAB38/ARL4A/RHOJ/GBP3/RASD1/RASL12/GBP1/GMPPB/GBP4/GCH1/RAB33A/GFM1/ADA/GLUD1/RAB2B/RAB40B/RHOB/SEPHS1/GNA13/RAB4A/RHOBTB3/GNA12/EHD1/RHOU/GEM/GNL3/ADORA1/RAB32/RAB3A/ARF6/ARF1/RAB18/ARHGEF5/ARF3/ATL1/RAB9B/ARL9/MPPED2/NPR2/RALA/RANBP17/CDC42/NMUR2/RAB31	58
MF	GO:0042626	ATPase activity, coupled to transmembrane movement of substances	20/2275	115/17697	0.09711	0.5365	0.4903	TAP1/TAP2/ABCA1/ATP6V1E2/ATP6V0B/ATP6V0E2/PCYOX1/ABCA5/ABCC1/ABCB10/ABCD1/ABCC2/ABCG2/ATP2A2/RALBP1/ATP1A4/TAPBP/ATP13A2/ATP6V1E1/ABCC11	20
MF	GO:0043492	ATPase activity, coupled to movement of substances	20/2275	115/17697	0.09711	0.5365	0.4903	TAP1/TAP2/ABCA1/ATP6V1E2/ATP6V0B/ATP6V0E2/PCYOX1/ABCA5/ABCC1/ABCB10/ABCD1/ABCC2/ABCG2/ATP2A2/RALBP1/ATP1A4/TAPBP/ATP13A2/ATP6V1E1/ABCC11	20
MF	GO:0001882	nucleoside binding	59/2275	389/17697	0.09855	0.5418	0.4952	MX1/TUBB3/RAB23/EHD4/IFI44L/MX2/DIRAS1/GBP2/DAPK1/RAB9A/RAB13/GBP5/RERG/RRAD/RAB38/ARL4A/RHOJ/GBP3/RASD1/RASL12/GBP1/GMPPB/GBP4/GCH1/RAB33A/GFM1/ADA/GLUD1/RAB2B/RAB40B/RHOB/SEPHS1/GNA13/RAB4A/RHOBTB3/GNA12/EHD1/RHOU/GEM/GNL3/ADORA1/RAB32/RAB3A/ARF6/ARF1/RAB18/ARHGEF5/ARF3/ATL1/ACTN4/RAB9B/ARL9/MPPED2/NPR2/RALA/RANBP17/CDC42/NMUR2/RAB31	59