ONTOLOGY	ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	qvalue	geneID	Count
KEGG	hsa05163	Human cytomegalovirus infection	40/792	225/8135	0.0001137	0.03718	0.03423	RB1/ARHGEF1/CDKN2A/MAPK12/HLA-G/RAC2/GNB3/GNA11/B2M/GNG12/CALM3/EIF4EBP1/ITPR3/ITGB3/AKT1/CXCL12/GNG10/GNB4/PTGER3/HLA-A/CDK4/IRF3/HLA-B/CRK/HLA-F/TNFRSF1A/ELK1/CASP3/ATF4/RAC1/MAP2K1/MAPK3/CREB3L4/ADCY3/BCAR1/MYC/PRKACA/GRB2/CHUK/TRADD	40
KEGG	hsa05165	Human papillomavirus infection	51/792	331/8135	0.0005685	0.09295	0.08558	RB1/HLA-G/COL6A1/LAMA4/ITGA5/THBS4/EIF4EBP1/WNT3/NOTCH4/PPP2R2A/PPP2R3C/ITGA2B/ITGB3/AKT1/COL6A6/COMP/HLA-A/CCNA2/FZD2/CDK4/ATP6V0C/IRF3/AXIN1/HLA-B/ATP6V0D1/FZD4/ATP6V0E1/HLA-F/TNFRSF1A/ATP6V1B1/LAMA2/CHD4/CASP3/WNT9B/ATP6V1A/PPP2R1A/COL6A2/LAMC1/COL4A3/MAP2K1/MAPK3/CREB3L4/FZD10/PRKACA/GRB2/RBL2/CHUK/TRADD/COL9A2/PPP2R5D/IKBKE	51
KEGG	hsa00480	Glutathione metabolism	14/792	58/8135	0.001058	0.1153	0.1062	GSTT2/PGD/RRM2B/GSTT2B/CHAC1/MGST3/GPX3/SMS/RRM2/SRM/GSTM5/ODC1/GCLM/IDH2	14
KEGG	hsa04350	TGF-beta signaling pathway	19/792	94/8135	0.001533	0.1159	0.1067	TGFB3/FMOD/TGIF2/NEO1/TGFB1/FBN1/ID4/DCN/SMAD9/ACVR1C/SMAD6/BMP7/INHBC/BMP6/PPP2R1A/MAPK3/E2F4/MYC/ACVR1	19
KEGG	hsa05132	Salmonella infection	39/792	249/8135	0.001812	0.1159	0.1067	KIF5C/MAPK12/FOS/ACTR1B/DCTN4/LY96/VPS41/TNFSF10/RHOG/TUBA3C/DYNLRB2/TUBA1C/TUBA4A/AKT1/RAB9B/MYO6/GAPDH/MLKL/DCTN6/HSP90AB1/TNFRSF1A/CD14/CASP3/AHNAK/MAP2K3/ARPC4/RAC1/KLC2/MAP2K1/MAPK3/RAB5B/NCKAP1/TXN/MYC/KIF5B/CHUK/TRADD/TUBB6/MYD88	39
KEGG	hsa04218	Cellular senescence	27/792	156/8135	0.002128	0.1159	0.1067	MRAS/RB1/CDKN2A/TGFB3/MAPK12/HLA-G/CALM3/LIN52/EIF4EBP1/ITPR3/TGFB1/AKT1/HLA-A/CCNA2/CDK4/HLA-B/SLC25A5/HLA-F/HIPK2/GATA4/MAP2K3/MAP2K1/MAPK3/E2F4/HIPK4/MYC/RBL2	27
KEGG	hsa04210	Apoptosis	24/792	136/8135	0.002822	0.1318	0.1214	DDIT3/FOS/CTSC/TNFSF10/PARP2/ITPR3/ENDOG/TUBA3C/TUBA1C/TUBA4A/AKT1/HTRA2/XIAP/CTSO/TNFRSF1A/EIF2S1/CASP3/ATF4/IL3RA/MAP2K1/MAPK3/CHUK/TRADD/NGF	24
KEGG	hsa03040	Spliceosome	25/792	147/8135	0.003881	0.1587	0.1461	DHX38/SNRPA/HNRNPM/EIF4A3/WBP11/PRPF31/SF3B4/SF3B2/HSPA2/PRPF8/LSM4/DDX23/XAB2/SNRNP70/PUF60/BCAS2/EFTUD2/DHX16/SF3B3/CTNNBL1/SNRPA1/PPIL1/SNRPD3/SF3A2/FUS	25
KEGG	hsa05225	Hepatocellular carcinoma	27/792	168/8135	0.006106	0.2218	0.2042	RB1/CDKN2A/GSTT2/TGFB3/ACTL6B/GSTT2B/SMARCB1/WNT3/SMARCC2/TGFB1/MGST3/HMOX1/TERC/AKT1/FZD2/CDK4/GSTM5/AXIN1/ACTL6A/FZD4/ELK1/WNT9B/MAP2K1/MAPK3/FZD10/MYC/GRB2	27
KEGG	hsa04010	MAPK signaling pathway	42/792	294/8135	0.006881	0.225	0.2071	MRAS/CACNB3/DDIT3/TGFB3/MAPK12/RAC2/MAPKAPK3/NTF3/FOS/KITLG/GNG12/HSPA2/MAPK8IP3/TEK/TGFB1/AKT1/ECSIT/CACNA2D3/MAP2K5/CRK/TNFRSF1A/EPHA2/DUSP8/CD14/ELK1/CASP3/ATF4/STK3/MAP2K3/RAC1/MAP2K1/MAPK3/MYC/PRKACA/CACNG3/GRB2/CHUK/NTRK2/CACNA1H/TRADD/NGF/MYD88	42
KEGG	hsa05166	Human T-cell leukemia virus 1 infection	33/792	222/8135	0.008771	0.2297	0.2114	RB1/CDKN2A/TGFB3/HLA-G/FOS/B2M/GPS2/HLA-DRA/TGFB1/LCK/AKT1/TSPO/HLA-A/CCNA2/CDK4/XIAP/TRRAP/HLA-B/ANAPC5/SLC25A5/HLA-F/TNFRSF1A/ELK1/ATF4/MAP2K1/MAPK3/CREB3L4/ADCY3/MYC/PRKACA/MSX1/HLA-DOB/CHUK	33
KEGG	hsa05022	Pathways of neurodegeneration - multiple diseases	62/792	476/8135	0.009737	0.2297	0.2114	COX7B/ATP2A3/KIF5C/DDIT3/MAPK12/UQCRC1/ACTR1B/DCTN4/TRAP1/ATXN3L/PSEN2/ADRM1/HSPA5/CALM3/WNT3/ATG2A/CYC1/UQCRH/ITPR3/TUBA3C/CYBB/NDUFA4L2/GPX3/TUBA1C/HIP1/RB1CC1/TUBA4A/APP/ULK1/HTRA2/PSMC5/DNAH2/PSMD2/FZD2/AXIN1/UQCRQ/DCTN6/SLC25A5/COX6B2/FZD4/COX7C/TARDBP/IFT57/TNFRSF1A/RYR3/EIF2S1/CASP3/WNT9B/ATF4/MAP2K3/RAC1/KLC2/NDUFV1/MAP2K1/MAPK3/NEFM/PSMA2/FZD10/KIF5B/SNCA/TUBB6/FUS	62
KEGG	hsa04512	ECM-receptor interaction	16/792	88/8135	0.01009	0.2297	0.2114	CD47/COL6A1/LAMA4/ITGA5/THBS4/ITGA2B/SV2A/ITGB3/COL6A6/COMP/LAMA2/COL6A2/LAMC1/COL4A3/GP9/COL9A2	16
KEGG	hsa05145	Toxoplasmosis	19/792	112/8135	0.01127	0.2297	0.2114	TGFB3/MAPK12/LAMA4/LY96/HSPA2/HLA-DRA/TGFB1/AKT1/XIAP/CD40LG/TNFRSF1A/LAMA2/CASP3/LAMC1/MAP2K3/MAPK3/HLA-DOB/CHUK/MYD88	19
KEGG	hsa04145	Phagosome	24/792	152/8135	0.01162	0.2297	0.2114	HLA-G/ITGA5/THBS4/HLA-DRA/TUBA3C/CYBB/TUBA1C/ITGB3/TUBA4A/COMP/SEC22B/HLA-A/ATP6V0C/HLA-B/ATP6V0D1/ATP6V0E1/HLA-F/ATP6V1B1/CD14/ATP6V1A/RAC1/RAB5B/HLA-DOB/TUBB6	24
KEGG	hsa05416	Viral myocarditis	12/792	60/8135	0.01167	0.2297	0.2114	HLA-G/RAC2/HLA-DRA/HLA-A/CD40LG/HLA-B/HLA-F/LAMA2/CASP3/SGCA/RAC1/HLA-DOB	12
KEGG	hsa03410	Base excision repair	8/792	33/8135	0.01194	0.2297	0.2114	XRCC1/POLE/NTHL1/PARP2/POLD1/MUTYH/APEX2/POLD2	8
KEGG	hsa05010	Alzheimer disease	51/792	384/8135	0.01277	0.2321	0.2136	COX7B/ATP2A3/KIF5C/DDIT3/ADAM10/UQCRC1/PSEN2/ADRM1/CALM3/WNT3/ATG2A/CYC1/UQCRH/ITPR3/TUBA3C/CYBB/NDUFA4L2/TUBA1C/RB1CC1/TUBA4A/APP/AKT1/ULK1/PSMC5/GAPDH/LRP1/PSMD2/FZD2/AXIN1/UQCRQ/SLC25A5/SLC39A11/COX6B2/FZD4/COX7C/TNFRSF1A/RYR3/EIF2S1/CASP3/WNT9B/ATF4/KLC2/NDUFV1/MAP2K1/MAPK3/PSMA2/FZD10/KIF5B/CHUK/SNCA/TUBB6	51
KEGG	hsa04934	Cushing syndrome	24/792	155/8135	0.01461	0.2404	0.2213	RB1/CDKN2A/GNA11/WNT3/CYP11A1/ITPR3/ARMC5/ORAI1/AIP/MEN1/FZD2/CDK4/AXIN1/KCNK3/FZD4/WNT9B/ATF4/MAP2K1/MAPK3/CREB3L4/ADCY3/FZD10/PRKACA/CACNA1H	24
KEGG	hsa05020	Prion disease	38/792	273/8135	0.0147	0.2404	0.2213	NCAM2/COX7B/KIF5C/DDIT3/MAPK12/UQCRC1/RAC2/ADRM1/HSPA5/HSPA2/CYC1/UQCRH/ITPR3/TUBA3C/CYBB/NDUFA4L2/TUBA1C/TUBA4A/PSMC5/PSMD2/UQCRQ/SLC25A5/COX6B2/COX7C/RYR3/EIF2S1/CASP3/ATF4/LAMC1/RAC1/KLC2/NDUFV1/MAPK3/CREB3L4/PSMA2/PRKACA/KIF5B/TUBB6	38
KEGG	hsa04722	Neurotrophin signaling pathway	19/792	119/8135	0.02071	0.3189	0.2936	MAPK12/NTF3/PSEN2/CALM3/ARHGDIA/AKT1/MAP2K5/CRK/ZNF274/ATF4/RAC1/SH2B3/MAP2K1/MAPK3/IRAK3/GRB2/SH2B2/NTRK2/NGF	19
KEGG	hsa05170	Human immunodeficiency virus 1 infection	30/792	212/8135	0.02286	0.3189	0.2936	MAPK12/HLA-G/RAC2/FOS/GNB3/GNA11/B2M/BST2/CUL4A/GNG12/CALM3/ITPR3/AKT1/GNG10/GNB4/HLA-A/IRF3/HLA-B/CRK/HLA-F/TNFRSF1A/CASP3/MAP2K3/RAC1/MAP2K1/MAPK3/LIMK2/CHUK/TRADD/MYD88	30
KEGG	hsa00270	Cysteine and methionine metabolism	10/792	51/8135	0.02325	0.3189	0.2936	MPST/BCAT2/GOT2/ADI1/SMS/SRM/AHCY/MAT2B/BHMT/GCLM	10
KEGG	hsa03015	mRNA surveillance pathway	16/792	97/8135	0.02433	0.3189	0.2936	EIF4A3/PABPC1L2A/SMG5/RNPS1/PABPC4L/PABPC4/PPP2R2A/PPP2R3C/UPF1/SMG1/TARDBP/PPP2R1A/UPF3A/NXT2/PPP2R5D/FUS	16
KEGG	hsa04151	PI3K-Akt signaling pathway	46/792	354/8135	0.02481	0.3189	0.2936	MLST8/NTF3/GNB3/COL6A1/PKN3/G6PC3/LAMA4/KITLG/ITGA5/THBS4/GNG12/EIF4EBP1/GYS1/TEK/DDIT4/PPP2R2A/PPP2R3C/ITGA2B/ITGB3/AKT1/COL6A6/GNG10/COMP/GNB4/CDK4/HSP90AB1/EPHA2/LAMA2/ATF4/IL3RA/PPP2R1A/COL6A2/LAMC1/COL4A3/RAC1/MAP2K1/MAPK3/CREB3L4/MYC/GRB2/RBL2/CHUK/NTRK2/COL9A2/PPP2R5D/NGF	46
KEGG	hsa05014	Amyotrophic lateral sclerosis	47/792	364/8135	0.02596	0.3189	0.2936	COX7B/KIF5C/DDIT3/MAPK12/UQCRC1/ACTR1B/DCTN4/ADRM1/HSPA5/UBQLN4/ATG2A/CYC1/UQCRH/ITPR3/TUBA3C/NDUFA4L2/GPX3/TUBA1C/RB1CC1/TUBA4A/ULK1/PSMC5/DNAH2/PSMD2/NUP93/UQCRQ/DCTN6/COX6B2/COX7C/TARDBP/TNFRSF1A/EIF2S1/CASP3/ATF4/MAP2K3/RAC1/KLC2/NDUFV1/NEFM/PSMA2/NXT2/SETX/NUP88/NUP62/KIF5B/TUBB6/FUS	47
KEGG	hsa05410	Hypertrophic cardiomyopathy	15/792	90/8135	0.02633	0.3189	0.2936	CACNB3/ATP2A3/TGFB3/ITGA5/EMD/MYL3/TGFB1/PRKAB2/ITGA2B/ITGB3/CACNA2D3/LAMA2/SGCA/CACNG3/EDN1	15
KEGG	hsa04150	mTOR signaling pathway	23/792	156/8135	0.02809	0.328	0.302	MLST8/SLC7A5/EIF4EBP1/WNT3/DDIT4/AKT1/ULK1/STRADB/FZD2/FZD4/TNFRSF1A/ATP6V1B1/RRAGB/WNT9B/ATP6V1A/MAP2K1/MAPK3/CLIP1/FZD10/GRB2/CHUK/PRR5/WDR24	23
KEGG	hsa05222	Small cell lung cancer	15/792	92/8135	0.03144	0.3447	0.3173	RB1/ZBTB17/RARB/LAMA4/ITGA2B/AKT1/CDK4/XIAP/RXRB/LAMA2/CASP3/LAMC1/COL4A3/MYC/CHUK	15
KEGG	hsa01210	2-Oxocarboxylic acid metabolism	5/792	19/8135	0.03162	0.3447	0.3173	IDH3B/ACY1/BCAT2/GOT2/IDH2	5
KEGG	hsa04612	Antigen processing and presentation	13/792	78/8135	0.03701	0.375	0.3452	HLA-G/B2M/PSME3/HSPA5/HSPA2/HLA-DRA/KLRC4/HLA-A/HLA-B/HSP90AB1/HLA-F/RFXANK/HLA-DOB	13
KEGG	hsa04071	Sphingolipid signaling pathway	18/792	119/8135	0.03872	0.375	0.3452	MAPK12/RAC2/PPP2R2A/PPP2R3C/SGMS2/AKT1/PLD2/SMPD2/DEGS1/SGPL1/TNFRSF1A/PPP2R1A/RAC1/MAP2K1/MAPK3/SPTLC1/TRADD/PPP2R5D	18
KEGG	hsa00670	One carbon pool by folate	5/792	20/8135	0.03889	0.375	0.3452	MTHFR/MTHFD1L/MTHFD1/ALDH1L2/ATIC	5
KEGG	hsa05012	Parkinson disease	35/792	266/8135	0.03936	0.375	0.3452	COX7B/KIF5C/DDIT3/UQCRC1/TRAP1/ADRM1/HSPA5/CALM3/CYC1/UQCRH/ITPR3/TUBA3C/NDUFA4L2/TUBA1C/TUBA4A/HTRA2/PSMC5/PSMD2/UQCRQ/SLC25A5/SLC39A11/COX6B2/COX7C/RYR3/EIF2S1/CASP3/ATF4/KLC2/NDUFV1/PSMA2/TXN/PRKACA/KIF5B/SNCA/TUBB6	35
KEGG	hsa05205	Proteoglycans in cancer	28/792	205/8135	0.04067	0.375	0.3452	MRAS/TWIST1/ARHGEF1/MAPK12/GPC3/ITGA5/WNT3/ITPR3/TGFB1/DCN/IQGAP1/ITGB3/AKT1/PDCD4/FZD2/FZD4/ELK1/CASP3/WNT9B/RAC1/MAP2K1/MAPK3/FZD10/MYC/PRKACA/GRB2/LUM/PPP1R12C	28
KEGG	hsa03440	Homologous recombination	8/792	41/8135	0.04128	0.375	0.3452	TOP3B/POLD1/BRCC3/BRIP1/RAD54L/MUS81/UIMC1/POLD2	8
KEGG	hsa05414	Dilated cardiomyopathy	15/792	96/8135	0.04379	0.387	0.3563	CACNB3/ATP2A3/TGFB3/ITGA5/EMD/MYL3/TGFB1/ITGA2B/ITGB3/CACNA2D3/LAMA2/SGCA/ADCY3/PRKACA/CACNG3	15
KEGG	hsa04932	Non-alcoholic fatty liver disease	22/792	155/8135	0.04514	0.3884	0.3576	COX7B/DDIT3/MAPK12/UQCRC1/FOS/NR1H3/CYC1/UQCRH/TGFB1/PRKAB2/NDUFA4L2/AKT1/UQCRQ/COX6B2/COX7C/TNFRSF1A/CYP2E1/EIF2S1/CASP3/ATF4/RAC1/NDUFV1	22
KEGG	hsa05016	Huntington disease	39/792	306/8135	0.04733	0.3937	0.3625	COX7B/KIF5C/UQCRC1/ACTR1B/DCTN4/AP2A2/ADRM1/POLR2E/ATG2A/CYC1/UQCRH/POLR2J/TUBA3C/AP2S1/NDUFA4L2/GPX3/TUBA1C/HIP1/RB1CC1/TUBA4A/ULK1/PSMC5/DNAH2/PSMD2/UQCRQ/DCTN6/SLC25A5/COX6B2/COX7C/IFT57/CASP3/POLR2A/KLC2/NDUFV1/CREB3L4/PSMA2/KIF5B/TUBB6/CLTB	39
KEGG	hsa05418	Fluid shear stress and atherosclerosis	20/792	139/8135	0.04816	0.3937	0.3625	GSTT2/MAPK12/RAC2/FOS/GSTT2B/CALM3/MGST3/ITGA2B/HMOX1/ITGB3/AKT1/GSTM5/MAP2K5/HSP90AB1/TNFRSF1A/RAC1/TXN/ACVR1/CHUK/EDN1	20
KEGG	hsa05144	Malaria	9/792	50/8135	0.04975	0.3968	0.3653	TGFB3/THBS4/KLRB1/TGFB1/LRP1/COMP/CD40LG/GYPA/MYD88	9
KEGG	hsa04142	Lysosome	19/792	132/8135	0.05295	0.4027	0.3707	CTSC/CD68/DMXL2/ARSG/NAGPA/GNS/LAPTM4B/ABCA2/GGA3/ABCB9/ATP6V0C/AP3M2/ATP6V0D1/CTSO/IDS/CLN3/ENTPD4/NPC2/CLTB	19
KEGG	hsa04728	Dopaminergic synapse	19/792	132/8135	0.05295	0.4027	0.3707	KIF5C/MAPK12/FOS/GNB3/GNG12/CALM3/ITPR3/PPP2R2A/PPP2R3C/AKT1/GNG10/GNB4/DRD4/ATF4/PPP2R1A/CREB3L4/PRKACA/KIF5B/PPP2R5D	19
KEGG	hsa04962	Vasopressin-regulated water reabsorption	8/792	44/8135	0.05931	0.4341	0.3997	DCTN4/ARHGDIA/AQP2/DCTN6/RAB5B/CREB3L4/ADCY3/PRKACA	8
KEGG	hsa03008	Ribosome biogenesis in eukaryotes	16/792	109/8135	0.06189	0.4341	0.3997	POP1/NAT10/DKC1/RRP7A/POP5/UTP6/PWP2/TBL3/EIF6/SBDS/RPP25/NMD3/GNL2/NXT2/SNORD3A/EMG1	16
KEGG	hsa05212	Pancreatic cancer	12/792	76/8135	0.0624	0.4341	0.3997	RB1/CDKN2A/TGFB3/RAC2/TGFB1/AKT1/PLD2/CDK4/RAC1/MAP2K1/MAPK3/CHUK	12
KEGG	hsa05220	Chronic myeloid leukemia	12/792	76/8135	0.0624	0.4341	0.3997	RB1/CDKN2A/TGFB3/TGFB1/AKT1/CDK4/CRK/MAP2K1/MAPK3/MYC/GRB2/CHUK	12
KEGG	hsa05208	Chemical carcinogenesis - reactive oxygen species	29/792	223/8135	0.0642	0.4374	0.4026	AKR1C3/COX7B/GSTT2/MAPK12/UQCRC1/FOS/GSTT2B/CYP1B1/CYC1/UQCRH/AKR1C4/NDUFA4L2/MGST3/HMOX1/AKT1/PLD2/PTPN1/GSTM5/UQCRQ/SLC25A5/COX6B2/COX7C/CYP2E1/RAC1/NDUFV1/MAP2K1/MAPK3/GRB2/CHUK	29
KEGG	hsa05330	Allograft rejection	7/792	38/8135	0.07088	0.4603	0.4238	HLA-G/HLA-DRA/HLA-A/CD40LG/HLA-B/HLA-F/HLA-DOB	7
KEGG	hsa04910	Insulin signaling pathway	19/792	137/8135	0.0718	0.4603	0.4238	PYGB/G6PC3/INPPL1/CALM3/EIF4EBP1/GYS1/PRKAB2/AKT1/PTPN1/PHKG2/CRK/PTPRF/ELK1/PRKAR1A/MAP2K1/MAPK3/PRKACA/GRB2/SH2B2	19
KEGG	hsa05135	Yersinia infection	19/792	137/8135	0.0718	0.4603	0.4238	ARHGEF1/MAPK12/RAC2/FOS/ITGA5/RHOG/LCK/AKT1/IRF3/CRK/SKAP2/MAP2K3/ARPC4/RAC1/MAP2K1/MAPK3/BCAR1/CHUK/MYD88	19
KEGG	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	11/792	70/8135	0.0744	0.4679	0.4308	ADAM10/MAPK12/CSK/ATP6V0C/ATP6V0D1/ATP6V0E1/ATP6V1B1/CASP3/ATP6V1A/RAC1/CHUK	11
KEGG	hsa04260	Cardiac muscle contraction	13/792	87/8135	0.07726	0.4739	0.4363	CACNB3/COX7B/ATP2A3/UQCRC1/MYL3/CYC1/UQCRH/CACNA2D3/UQCRQ/COX6B2/TRDN/COX7C/CACNG3	13
KEGG	hsa04510	Focal adhesion	26/792	201/8135	0.08039	0.4739	0.4363	RAC2/COL6A1/LAMA4/ITGA5/THBS4/PARVG/ACTN1/ITGA2B/ITGB3/AKT1/COL6A6/COMP/XIAP/CRK/LAMA2/ELK1/COL6A2/LAMC1/COL4A3/RAC1/MAP2K1/MAPK3/BCAR1/GRB2/COL9A2/PPP1R12C	26
KEGG	hsa03420	Nucleotide excision repair	8/792	47/8135	0.08164	0.4739	0.4363	POLE/CUL4A/POLD1/ERCC1/GTF2H4/ERCC6/ERCC3/POLD2	8
KEGG	hsa04540	Gap junction	13/792	88/8135	0.083	0.4739	0.4363	CSNK1D/GNA11/ITPR3/TUBA3C/TUBA1C/TUBA4A/MAP2K5/MAP2K1/MAPK3/ADCY3/PRKACA/GRB2/TUBB6	13
KEGG	hsa05169	Epstein-Barr virus infection	26/792	202/8135	0.08416	0.4739	0.4363	RB1/MAPK12/HLA-G/B2M/ADRM1/HLA-DRA/AKT1/PSMC5/HLA-A/PSMD2/CCNA2/CDK4/IRF3/ENTPD8/HLA-B/HLA-F/CIR1/CASP3/MAP2K3/RAC1/MYC/HLA-DOB/CHUK/TRADD/MYD88/IKBKE	26
KEGG	hsa00983	Drug metabolism - other enzymes	12/792	80/8135	0.08529	0.4739	0.4363	GSTT2/RRM2B/UCKL1/GSTT2B/TK1/MGST3/RRM2/IMPDH2/GSTM5/CYP2E1/UGT1A3/UMPS	12
KEGG	hsa05223	Non-small cell lung cancer	11/792	72/8135	0.08732	0.4739	0.4363	RB1/CDKN2A/KIF5C/RARB/AKT1/CDK4/RXRB/MAP2K1/MAPK3/KIF5B/GRB2	11
KEGG	hsa05167	Kaposi sarcoma-associated herpesvirus infection	25/792	194/8135	0.08806	0.4739	0.4363	RB1/MAPK12/HLA-G/FOS/GNB3/GNG12/CALM3/ITPR3/AKT1/GNG10/GNB4/HLA-A/CDK4/IRF3/HLA-B/HLA-F/TNFRSF1A/CASP3/RAC1/MAP2K1/MAPK3/MYC/CHUK/TRADD/IKBKE	25
KEGG	hsa00280	Valine, leucine and isoleucine degradation	8/792	48/8135	0.09005	0.4739	0.4363	MCEE/IVD/ACADSB/BCAT2/HADHB/ACADS/ALDH3A2/AUH	8
KEGG	hsa01522	Endocrine resistance	14/792	98/8135	0.092	0.4739	0.4363	RB1/CDKN2A/MAPK12/FOS/NOTCH4/AKT1/CDK4/DLL3/MAP2K1/MAPK3/CARM1/ADCY3/PRKACA/GRB2	14
KEGG	hsa01524	Platinum drug resistance	11/792	73/8135	0.09427	0.4739	0.4363	CDKN2A/GSTT2/GSTT2B/ATP7B/ERCC1/MGST3/AKT1/XIAP/GSTM5/CASP3/MAPK3	11
KEGG	hsa04927	Cortisol synthesis and secretion	10/792	65/8135	0.09646	0.4739	0.4363	GNA11/CYP11A1/ITPR3/ORAI1/KCNK3/ATF4/CREB3L4/ADCY3/PRKACA/CACNA1H	10
KEGG	hsa04144	Endocytosis	31/792	251/8135	0.09766	0.4739	0.4363	ARAP3/KIF5C/HLA-G/ARAP1/AP2A2/HSPA2/FOLR3/AP2S1/SMAP2/GRK5/VPS37C/PLD2/TSG101/SH3GL3/HLA-A/VPS37B/VPS37A/HLA-B/HLA-F/ASAP1/ARFGAP1/ARPC4/GRK7/RAB5B/VPS26B/SH3GL1/CHMP6/RAB11FIP5/KIF5B/RAB35/CLTB	31
KEGG	hsa05219	Bladder cancer	7/792	41/8135	0.09843	0.4739	0.4363	RB1/CDKN2A/DAPK3/CDK4/MAP2K1/MAPK3/MYC	7
KEGG	hsa00520	Amino sugar and nucleotide sugar metabolism	8/792	49/8135	0.09894	0.4739	0.4363	TSTA3/PGM1/GNPNAT1/CYB5R4/UAP1/GMPPA/AMDHD2/GNPDA2	8
KEGG	hsa04550	Signaling pathways regulating pluripotency of stem cells	19/792	143/8135	0.0998	0.4739	0.4363	MAPK12/WNT3/ID4/AKT1/HESX1/SMAD9/ACVR1C/FZD2/AXIN1/FZD4/PCGF1/WNT9B/INHBC/MAP2K1/MAPK3/FZD10/MYC/ACVR1/GRB2	19
KEGG	hsa05417	Lipid and atherosclerosis	27/792	215/8135	0.09999	0.4739	0.4363	ARHGEF1/VLDLR/DDIT3/MAPK12/FOS/LY96/HSPA5/CALM3/HSPA2/TNFSF10/CYBB/AKT1/CD40LG/IRF3/RXRB/HSP90AB1/TNFRSF1A/CD14/EIF2S1/CASP3/ATF4/MAP2K3/RAC1/MAPK3/CHUK/MYD88/IKBKE	27
KEGG	hsa04141	Protein processing in endoplasmic reticulum	22/792	171/8135	0.1058	0.4906	0.4517	DDIT3/RRBP1/ATXN3L/HSPA5/HSPBP1/HSPA2/UBQLN4/RPN2/STUB1/P4HB/SAR1A/PREB/UBXN6/SAR1B/HSP90AB1/PRKCSH/AMFR/OS9/EIF2S1/ATF4/DNAJB1/UBXN1	22
KEGG	hsa05110	Vibrio cholerae infection	8/792	50/8135	0.1083	0.4906	0.4517	TJP2/ATP6V0C/ATP6V0D1/ATP6V0E1/ATP6V1B1/ATP6V1A/ADCY3/PRKACA	8
KEGG	hsa01230	Biosynthesis of amino acids	11/792	75/8135	0.1091	0.4906	0.4517	IDH3B/ACY1/BCAT2/TPI1/TKT/GOT2/ENO1/GAPDH/ASL/MAT2B/IDH2	11
KEGG	hsa04935	Growth hormone synthesis, secretion and action	16/792	119/8135	0.1141	0.4906	0.4517	MAPK12/FOS/GNA11/ITPR3/AKT1/CRK/SSTR2/ATF4/MAP2K3/MAP2K1/MAPK3/CREB3L4/ADCY3/BCAR1/PRKACA/GRB2	16
KEGG	hsa04360	Axon guidance	23/792	182/8135	0.1156	0.4906	0.4517	RAC2/SEMA3A/RHOD/PLXNA3/SEMA4F/NEO1/EPHA5/PLXNA1/CXCL12/SLIT3/PLXNA4/EPHA4/EPHA3/LRRC4C/PLXNB1/DPYSL2/EPHA2/ROBO3/BMP7/RAC1/MAPK3/LIMK2/BOC	23
KEGG	hsa04912	GnRH signaling pathway	13/792	93/8135	0.1156	0.4906	0.4517	MAPK12/GNA11/CALM3/ITPR3/PLD2/ELK1/ATF4/MAP2K3/MAP2K1/MAPK3/ADCY3/PRKACA/GRB2	13
KEGG	hsa05323	Rheumatoid arthritis	13/792	93/8135	0.1156	0.4906	0.4517	TGFB3/FOS/TNFRSF11A/HLA-DRA/TEK/TGFB1/CXCL12/ATP6V0C/ATP6V0D1/ATP6V0E1/ATP6V1B1/ATP6V1A/HLA-DOB	13
KEGG	hsa04966	Collecting duct acid secretion	5/792	27/8135	0.1159	0.4906	0.4517	ATP6V0C/ATP6V0D1/ATP6V0E1/ATP6V1B1/ATP6V1A	5
KEGG	hsa05133	Pertussis	11/792	76/8135	0.117	0.4906	0.4517	MAPK12/FOS/LY96/ITGA5/CALM3/IRF3/CD14/CASP3/C1S/MAPK3/MYD88	11
KEGG	hsa04940	Type I diabetes mellitus	7/792	43/8135	0.1196	0.4952	0.4559	HLA-G/HLA-DRA/HLA-A/HLA-B/HLA-F/CPE/HLA-DOB	7
KEGG	hsa04926	Relaxin signaling pathway	17/792	129/8135	0.1212	0.4955	0.4562	MAPK12/FOS/GNB3/GNG12/TGFB1/AKT1/GNG10/GNB4/ATF4/COL4A3/MAP2K1/MAPK3/CREB3L4/ADCY3/PRKACA/GRB2/EDN1	17
KEGG	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	11/792	77/8135	0.1253	0.5057	0.4655	CACNB3/ATP2A3/ITGA5/EMD/ITGA2B/ITGB3/CACNA2D3/LAMA2/SGCA/CACNG3/ACTN2	11
KEGG	hsa05210	Colorectal cancer	12/792	86/8135	0.1283	0.5116	0.471	TGFB3/RAC2/FOS/TGFB1/AKT1/AXIN1/CASP3/RAC1/MAP2K1/MAPK3/MYC/GRB2	12
KEGG	hsa03030	DNA replication	6/792	36/8135	0.1321	0.5206	0.4793	POLE/POLD1/MCM7/MCM2/RNASEH2A/POLD2	6
KEGG	hsa04721	Synaptic vesicle cycle	11/792	78/8135	0.1338	0.5208	0.4795	SLC1A1/AP2A2/AP2S1/SLC6A2/ATP6V0C/ATP6V0D1/ATP6V0E1/ATP6V1B1/ATP6V1A/SLC1A6/CLTB	11
KEGG	hsa03018	RNA degradation	11/792	79/8135	0.1426	0.5487	0.5052	PABPC1L2A/PABPC4L/LSM4/CNOT3/EDC3/PABPC4/ENO1/EXOSC10/CNOT7/EXOSC9/EXOSC5	11
KEGG	hsa04666	Fc gamma R-mediated phagocytosis	13/792	97/8135	0.1464	0.5522	0.5084	RAC2/INPPL1/SCIN/AKT1/PLD2/CRK/ASAP1/ARPC4/RAC1/MAP2K1/MAPK3/MARCKS/LIMK2	13
KEGG	hsa05130	Pathogenic Escherichia coli infection	24/792	197/8135	0.1469	0.5522	0.5084	MYO5A/ARHGEF1/MAPK12/FOS/TNFSF10/ABCF2/TUBA3C/MYH10/MYO1C/TUBA1C/TUBA4A/MYO6/GAPDH/BAIAP2L1/TNFRSF1A/CASP3/ARPC4/RAC1/MAPK3/NCKAP1/CHUK/TRADD/TUBB6/MYD88	24
KEGG	hsa05161	Hepatitis B	20/792	162/8135	0.1587	0.5887	0.542	RB1/TGFB3/MAPK12/FOS/TGFB1/AKT1/CCNA2/IRF3/ELK1/CASP3/ATF4/MAP2K3/MAP2K1/MAPK3/CREB3L4/MYC/GRB2/CHUK/MYD88/IKBKE	20
KEGG	hsa00900	Terpenoid backbone biosynthesis	4/792	22/8135	0.1602	0.5887	0.542	RCE1/MVK/PDSS1/GGPS1	4
KEGG	hsa00514	Other types of O-glycan biosynthesis	7/792	47/8135	0.1683	0.6115	0.563	PLOD3/B4GALT1/C1GALT1C1/OGT/POMT1/C1GALT1/GALNT6	7
KEGG	hsa00603	Glycosphingolipid biosynthesis - globo and isoglobo series	3/792	15/8135	0.1738	0.6246	0.575	GBGT1/A3GALT2/ST3GAL2	3
KEGG	hsa04916	Melanogenesis	13/792	101/8135	0.1812	0.6439	0.5928	KITLG/CALM3/WNT3/FZD2/FZD4/WNT9B/MAP2K1/MAPK3/CREB3L4/ADCY3/FZD10/PRKACA/EDN1	13
KEGG	hsa05203	Viral carcinogenesis	24/792	204/8135	0.1898	0.6674	0.6145	RB1/CDKN2A/HLA-G/SCIN/ACTN1/MRPS18B/GTF2H4/HLA-A/CCNA2/CDK4/IRF3/HLA-B/ATP6V0D1/HLA-F/CHD4/CASP3/ATF4/RAC1/MAPK3/CREB3L4/PRKACA/GRB2/RBL2/TRADD	24
KEGG	hsa03010	Ribosome	19/792	158/8135	0.1961	0.6821	0.628	MRPS2/MRPL12/MRPS6/MRPL34/MRPL4/RPL18/RPL23/RPL13/RPS5/RPS28/MRPL19/MRPL23/RPL35/MRPS10/RPL28/RPL23A/RPS7/RPL9/RPL36	19
KEGG	hsa04668	TNF signaling pathway	14/792	112/8135	0.1985	0.6831	0.6289	MAPK12/FOS/AKT1/MLKL/TNFRSF1A/CASP3/ATF4/MAP2K3/MAP2K1/MAPK3/CREB3L4/CHUK/TRADD/EDN1	14
KEGG	hsa05221	Acute myeloid leukemia	9/792	67/8135	0.201	0.6848	0.6304	EIF4EBP1/AKT1/CCNA2/CD14/MAP2K1/MAPK3/MYC/GRB2/CHUK	9
KEGG	hsa04725	Cholinergic synapse	14/792	113/8135	0.2077	0.6994	0.6439	FOS/GNB3/GNA11/GNG12/ITPR3/AKT1/GNG10/GNB4/ATF4/MAP2K1/MAPK3/CREB3L4/ADCY3/PRKACA	14
KEGG	hsa04620	Toll-like receptor signaling pathway	13/792	104/8135	0.2096	0.6994	0.6439	MAPK12/FOS/LY96/AKT1/IRF3/CD14/MAP2K3/RAC1/MAP2K1/MAPK3/CHUK/MYD88/IKBKE	13
KEGG	hsa05140	Leishmaniasis	10/792	77/8135	0.2132	0.7042	0.6483	TGFB3/MAPK12/FOS/HLA-DRA/TGFB1/CYBB/ELK1/MAPK3/HLA-DOB/MYD88	10
KEGG	hsa05332	Graft-versus-host disease	6/792	42/8135	0.2207	0.7217	0.6645	HLA-G/HLA-DRA/HLA-A/HLA-B/HLA-F/HLA-DOB	6
KEGG	hsa00330	Arginine and proline metabolism	7/792	51/8135	0.2242	0.7259	0.6683	AGMAT/GOT2/SMS/SRM/ALDH3A2/CKB/ODC1	7
KEGG	hsa04713	Circadian entrainment	12/792	97/8135	0.2322	0.7445	0.6855	FOS/GNB3/GNG12/CALM3/ITPR3/GNG10/GNB4/RYR3/MAPK3/ADCY3/PRKACA/CACNA1H	12
KEGG	hsa00071	Fatty acid degradation	6/792	43/8135	0.2371	0.7528	0.693	ACOX3/ACADSB/HADHB/ACADL/ACADS/ALDH3A2	6
KEGG	hsa04925	Aldosterone synthesis and secretion	12/792	98/8135	0.243	0.7584	0.6982	GNA11/CAMK1/CALM3/CYP11A1/ITPR3/ORAI1/KCNK3/ATF4/CREB3L4/ADCY3/PRKACA/CACNA1H	12
KEGG	hsa05207	Chemical carcinogenesis - receptor activation	24/792	212/8135	0.2457	0.7584	0.6982	RB1/GSTT2/FOS/GSTT2B/CYP1B1/EIF4EBP1/MGST3/AKT1/AIP/XIAP/GSTM5/RXRB/HSP90AB1/UGT1A3/DLL3/ATF4/MAP2K1/MAPK3/CREB3L4/ADCY3/MYC/PRKACA/GRB2/IKBKE	24
KEGG	hsa03013	Nucleocytoplasmic transport	13/792	108/8135	0.2503	0.7584	0.6982	XPOT/EIF4A3/RNPS1/THOC6/RANGAP1/UPF1/IPO4/NUP93/NMD3/UPF3A/NXT2/NUP88/NUP62	13
KEGG	hsa04640	Hematopoietic cell lineage	12/792	99/8135	0.254	0.7584	0.6982	CD24/CD9/KITLG/ITGA5/HLA-DRA/ITGA2B/ITGB3/GYPA/CD14/IL3RA/HLA-DOB/GP9	12
KEGG	hsa05320	Autoimmune thyroid disease	7/792	53/8135	0.2543	0.7584	0.6982	HLA-G/HLA-DRA/HLA-A/CD40LG/HLA-B/HLA-F/HLA-DOB	7
KEGG	hsa04380	Osteoclast differentiation	15/792	128/8135	0.2621	0.7584	0.6982	FOSB/MAPK12/FOS/TNFRSF11A/TGFB1/LCK/ITGB3/AKT1/TNFRSF1A/LILRB5/RAC1/MAP2K1/MAPK3/GRB2/CHUK	15
KEGG	hsa04933	AGE-RAGE signaling pathway in diabetic complications	12/792	100/8135	0.2652	0.7584	0.6982	TGFB3/MAPK12/F3/TGFB1/CYBB/AKT1/CDK4/CASP3/COL4A3/RAC1/MAPK3/EDN1	12
KEGG	hsa04390	Hippo signaling pathway	18/792	157/8135	0.2662	0.7584	0.6982	CSNK1D/TGFB3/GLI2/WNT3/TGFB1/PPP2R2A/FRMD6/FZD2/AXIN1/FZD4/BMP7/WNT9B/STK3/BMP6/PPP2R1A/DLG5/FZD10/MYC	18
KEGG	hsa05160	Hepatitis C	18/792	157/8135	0.2662	0.7584	0.6982	RB1/NR1H3/PSME3/PPP2R2A/AKT1/CDK4/IRF3/TNFRSF1A/EIF2S1/CASP3/PPP2R1A/MAP2K1/MAPK3/MYC/GRB2/CHUK/TRADD/IKBKE	18
KEGG	hsa04915	Estrogen signaling pathway	16/792	138/8135	0.2669	0.7584	0.6982	FOS/CALM3/HSPA2/ITPR3/AKT1/HSP90AB1/KRT9/ATF4/MAP2K1/MAPK3/CREB3L4/ADCY3/PRKACA/GRB2/KRT24/FKBP4	16
KEGG	hsa03250	Viral life cycle - HIV-1	8/792	63/8135	0.2675	0.7584	0.6982	MAP1S/BST2/SMARCB1/PIN1/TSG101/SERINC3/SUPT5H/CHMP6	8
KEGG	hsa03460	Fanconi anemia pathway	7/792	54/8135	0.2698	0.7584	0.6982	ATRIP/TOP3B/BRIP1/ERCC1/REV1/MUS81/FANCC	7
KEGG	hsa00512	Mucin type O-glycan biosynthesis	5/792	36/8135	0.2701	0.7584	0.6982	B4GALT5/C1GALT1C1/C1GALT1/ST3GAL2/GALNT6	5
KEGG	hsa04662	B cell receptor signaling pathway	10/792	82/8135	0.2739	0.7584	0.6982	RAC2/FOS/INPPL1/AKT1/LILRB5/RAC1/MAP2K1/MAPK3/GRB2/CHUK	10
KEGG	hsa04152	AMPK signaling pathway	14/792	120/8135	0.2772	0.7584	0.6982	G6PC3/EIF4EBP1/GYS1/PRKAB2/PPP2R2A/PPP2R3C/AKT1/ULK1/STRADB/CCNA2/PPP2R1A/CREB3L4/PPP2R5D/PFKFB3	14
KEGG	hsa05226	Gastric cancer	17/792	149/8135	0.2807	0.7584	0.6982	RB1/TGFB3/RARB/WNT3/TGFB1/TERC/AKT1/FZD2/AXIN1/RXRB/FZD4/WNT9B/MAP2K1/MAPK3/FZD10/MYC/GRB2	17
KEGG	hsa05142	Chagas disease	12/792	102/8135	0.288	0.7584	0.6982	TGFB3/MAPK12/FOS/GNA11/TGFB1/PPP2R2A/AKT1/TNFRSF1A/PPP2R1A/MAPK3/CHUK/MYD88	12
KEGG	hsa05146	Amoebiasis	12/792	102/8135	0.288	0.7584	0.6982	TGFB3/GNA11/LAMA4/ACTN1/TGFB1/LAMA2/CD14/CASP3/LAMC1/COL4A3/RAB5B/PRKACA	12
KEGG	hsa03050	Proteasome	6/792	46/8135	0.2882	0.7584	0.6982	PSME3/ADRM1/POMP/PSMC5/PSMD2/PSMA2	6
KEGG	hsa01250	Biosynthesis of nucleotide sugars	5/792	37/8135	0.2896	0.7584	0.6982	TSTA3/PGM1/GNPNAT1/UAP1/GMPPA	5
KEGG	hsa05216	Thyroid cancer	5/792	37/8135	0.2896	0.7584	0.6982	PAX8/RXRB/MAP2K1/MAPK3/MYC	5
KEGG	hsa04261	Adrenergic signaling in cardiomyocytes	17/792	150/8135	0.2901	0.7584	0.6982	CACNB3/ATP2A3/MAPK12/CALM3/MYL3/PPP2R2A/PPP2R3C/AKT1/CACNA2D3/ATF4/PPP2R1A/MAPK3/CREB3L4/ADCY3/PRKACA/CACNG3/PPP2R5D	17
KEGG	hsa04650	Natural killer cell mediated cytotoxicity	15/792	131/8135	0.2922	0.7584	0.6982	RAET1G/HLA-G/RAC2/ULBP1/ICAM2/TNFSF10/LCK/HLA-A/HLA-B/NCR2/CASP3/RAC1/MAP2K1/MAPK3/GRB2	15
KEGG	hsa04140	Autophagy - animal	16/792	141/8135	0.2962	0.7626	0.7021	MRAS/MLST8/DAPK3/ATG2A/VAMP8/DDIT4/RB1CC1/AKT1/ULK1/RAB33B/EIF2S1/RRAGB/MAP2K1/MAPK3/PRKACA/SNAP29	16
KEGG	hsa05214	Glioma	9/792	75/8135	0.3054	0.7688	0.7078	RB1/CDKN2A/CAMK1/CALM3/AKT1/CDK4/MAP2K1/MAPK3/GRB2	9
KEGG	hsa04657	IL-17 signaling pathway	11/792	94/8135	0.306	0.7688	0.7078	FOSB/MAPK12/FOS/IL17D/ANAPC5/HSP90AB1/CASP3/MAPK3/CHUK/TRADD/IKBKE	11
KEGG	hsa04936	Alcoholic liver disease	16/792	142/8135	0.3062	0.7688	0.7078	MAPK12/LY96/ACOX3/PRKAB2/AKT1/IRF3/ALDH3A2/TNFRSF1A/CYP2E1/CD14/CASP3/MAP2K3/CHUK/TRADD/MYD88/IKBKE	16
KEGG	hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	3/792	20/8135	0.308	0.7688	0.7078	CHPF2/B3GAT3/XYLT1	3
KEGG	hsa01232	Nucleotide metabolism	10/792	85/8135	0.3125	0.7691	0.7081	RRM2B/UCKL1/AMPD2/TK1/RRM2/IMPDH2/ENTPD8/AK5/ENTPD4/ADK	10
KEGG	hsa04724	Glutamatergic synapse	13/792	114/8135	0.316	0.7691	0.7081	GNB3/SLC1A1/GNG12/ITPR3/PLD2/GNG10/GNB4/SLC38A1/HOMER3/MAPK3/SLC1A6/ADCY3/PRKACA	13
KEGG	hsa05017	Spinocerebellar ataxia	16/792	143/8135	0.3162	0.7691	0.7081	ATP2A3/VLDLR/ATXN3L/ADRM1/ATG2A/ITPR3/RB1CC1/AKT1/ULK1/PSMC5/CIC/PSMD2/SLC25A5/PUM1/SLC1A6/PSMA2	16
KEGG	hsa05134	Legionellosis	7/792	57/8135	0.3175	0.7691	0.7081	HSPA2/SAR1A/SEC22B/SAR1B/CD14/CASP3/MYD88	7
KEGG	hsa00240	Pyrimidine metabolism	7/792	58/8135	0.3338	0.783	0.7208	RRM2B/UCKL1/TK1/RRM2/ENTPD8/UMPS/ENTPD4	7
KEGG	hsa05213	Endometrial cancer	7/792	58/8135	0.3338	0.783	0.7208	AKT1/AXIN1/ELK1/MAP2K1/MAPK3/MYC/GRB2	7
KEGG	hsa00030	Pentose phosphate pathway	4/792	30/8135	0.3338	0.783	0.7208	PGM1/PGD/RBKS/TKT	4
KEGG	hsa01523	Antifolate resistance	4/792	30/8135	0.3338	0.783	0.7208	MTHFR/FOLR3/ATIC/CHUK	4
KEGG	hsa04928	Parathyroid hormone synthesis, secretion and action	12/792	106/8135	0.3352	0.783	0.7208	ARHGEF1/FOS/GNA11/ITPR3/PLD2/RXRB/ATF4/MAP2K1/MAPK3/CREB3L4/ADCY3/PRKACA	12
KEGG	hsa04664	Fc epsilon RI signaling pathway	8/792	68/8135	0.3415	0.7841	0.7218	MAPK12/RAC2/AKT1/MAP2K3/RAC1/MAP2K1/MAPK3/GRB2	8
KEGG	hsa04110	Cell cycle	14/792	126/8135	0.342	0.7841	0.7218	RB1/PKMYT1/CDKN2A/ZBTB17/TGFB3/TGFB1/CCNA2/CDK4/MCM7/ANAPC5/MCM2/E2F4/MYC/RBL2	14
KEGG	hsa04922	Glucagon signaling pathway	12/792	107/8135	0.3473	0.7841	0.7218	PYGB/G6PC3/CALM3/GYS1/ITPR3/GCG/PRKAB2/AKT1/PHKG2/ATF4/CREB3L4/PRKACA	12
KEGG	hsa04370	VEGF signaling pathway	7/792	59/8135	0.3502	0.7841	0.7218	MAPK12/RAC2/MAPKAPK3/AKT1/RAC1/MAP2K1/MAPK3	7
KEGG	hsa05168	Herpes simplex virus 1 infection	51/792	495/8135	0.3531	0.7841	0.7218	ZNF354A/ZNF649/HLA-G/ZNF569/ZNF223/ZNF641/B2M/ZNF777/ITGA5/ZNF721/BST2/ZNF416/ZNF486/HLA-DRA/EIF4EBP1/ZNF554/ZNF337/ZNF597/ZNF573/ZNF700/ZNF746/ZNF343/ZNF234/ZNF324/ZNF317/ITGB3/AKT1/ZNF783/ZNF283/HLA-A/EIF2B2/IRF3/HLA-B/HLA-F/TNFRSF1A/ZNF417/ZNF860/EIF2S1/CASP3/EIF2B4/ZNF595/ZNF577/ZFP30/HLA-DOB/ZNF77/CHUK/TRADD/MYD88/IKBKE/ZNF229/ZNF470	51
KEGG	hsa05204	Chemical carcinogenesis - DNA adducts	8/792	69/8135	0.3567	0.7841	0.7218	GSTT2/GSTT2B/CYP1B1/CYP3A7/MGST3/GSTM5/CYP2E1/UGT1A3	8
KEGG	hsa05211	Renal cell carcinoma	8/792	69/8135	0.3567	0.7841	0.7218	TGFB3/TGFB1/AKT1/CRK/RAC1/MAP2K1/MAPK3/GRB2	8
KEGG	hsa04710	Circadian rhythm	4/792	31/8135	0.3568	0.7841	0.7218	CSNK1D/PRKAB2/RORB/CRY2	4
KEGG	hsa05224	Breast cancer	16/792	147/8135	0.3573	0.7841	0.7218	RB1/FOS/WNT3/NOTCH4/AKT1/FZD2/CDK4/AXIN1/FZD4/WNT9B/DLL3/MAP2K1/MAPK3/FZD10/MYC/GRB2	16
KEGG	hsa00220	Arginine biosynthesis	3/792	22/8135	0.3635	0.7923	0.7295	ACY1/GOT2/ASL	3
KEGG	hsa04371	Apelin signaling pathway	15/792	139/8135	0.3769	0.8016	0.738	MRAS/GNB3/GNG12/CALM3/MYL3/ITPR3/PRKAB2/AKT1/GNG10/GNB4/RYR3/MAP2K1/MAPK3/ADCY3/PRKACA	15
KEGG	hsa04913	Ovarian steroidogenesis	6/792	51/8135	0.3774	0.8016	0.738	AKR1C3/CYP1B1/CYP11A1/BMP6/ADCY3/PRKACA	6
KEGG	hsa04514	Cell adhesion molecules	16/792	149/8135	0.3782	0.8016	0.738	NCAM2/HLA-G/NRXN2/ICAM2/HLA-DRA/NLGN4X/NEO1/CNTNAP1/HLA-A/CDH15/CD40LG/HLA-B/LRRC4C/HLA-F/PTPRF/HLA-DOB	16
KEGG	hsa04215	Apoptosis - multiple species	4/792	32/8135	0.3798	0.8016	0.738	HTRA2/XIAP/TNFRSF1A/CASP3	4
KEGG	hsa00140	Steroid hormone biosynthesis	7/792	61/8135	0.3831	0.8016	0.738	AKR1C3/CYP1B1/CYP3A7/CYP11A1/AKR1C4/CYP2E1/UGT1A3	7
KEGG	hsa04520	Adherens junction	8/792	71/8135	0.3873	0.8016	0.738	RAC2/ACTN1/IQGAP1/PTPN1/YES1/PTPRF/RAC1/MAPK3	8
KEGG	hsa00515	Mannose type O-glycan biosynthesis	3/792	23/8135	0.391	0.8016	0.738	B4GALT1/POMT1/FUT4	3
KEGG	hsa03060	Protein export	3/792	23/8135	0.391	0.8016	0.738	HSPA5/IMMP1L/SPCS3	3
KEGG	hsa00600	Sphingolipid metabolism	6/792	52/8135	0.3954	0.8016	0.738	SGMS2/SMPD2/DEGS1/SGPL1/B4GALT6/SPTLC1	6
KEGG	hsa04068	FoxO signaling pathway	14/792	131/8135	0.3981	0.8016	0.738	TGFB3/MAPK12/G6PC3/TNFSF10/TGFB1/PRKAB2/AKT1/HOMER3/MAP2K1/MAPK3/GRB2/RBL2/CHUK/FBXO32	14
KEGG	hsa05164	Influenza A	18/792	171/8135	0.3998	0.8016	0.738	HLA-DRA/TNFSF10/AKT1/CDK4/IRF3/SLC25A5/TNFRSF1A/EIF2S1/CASP3/MAP2K1/MAPK3/NXT2/HLA-DOB/DNAJB1/CHUK/TRADD/MYD88/IKBKE	18
KEGG	hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	2/792	14/8135	0.4018	0.8016	0.738	B4GALT1/ST3GAL2	2
KEGG	hsa00051	Fructose and mannose metabolism	4/792	33/8135	0.4027	0.8016	0.738	TSTA3/TPI1/GMPPA/PFKFB3	4
KEGG	hsa04914	Progesterone-mediated oocyte maturation	11/792	102/8135	0.4075	0.8016	0.738	PKMYT1/MAPK12/CPEB1/AKT1/CCNA2/ANAPC5/HSP90AB1/MAP2K1/MAPK3/ADCY3/PRKACA	11
KEGG	hsa04014	Ras signaling pathway	24/792	232/8135	0.4081	0.8016	0.738	MRAS/RAC2/NTF3/GNB3/KITLG/GNG12/CALM3/TEK/AKT1/PLD2/GNG10/GNB4/EPHA2/ELK1/RAC1/MAP2K1/MAPK3/RAB5B/PRKACA/GRB2/CHUK/RASA4/NTRK2/NGF	24
KEGG	hsa04714	Thermogenesis	24/792	232/8135	0.4081	0.8016	0.738	MLST8/COX7B/MAPK12/UQCRC1/ACTL6B/SMARCB1/CYC1/UQCRH/SMARCC2/GCG/PRKAB2/NDUFA4L2/NDUFAF2/COX19/UQCRQ/COX6B2/ACTL6A/COX7C/MAP2K3/NDUFV1/CREB3L4/ADCY3/PRKACA/GRB2	24
KEGG	hsa04062	Chemokine signaling pathway	20/792	192/8135	0.4094	0.8016	0.738	RAC2/GNB3/GNG12/GRK5/AKT1/CXCL12/GNG10/GNB4/CRK/PPBP/RAC1/MAP2K1/MAPK3/GRK7/CXCR3/ADCY3/BCAR1/PRKACA/GRB2/CHUK	20
KEGG	hsa05217	Basal cell carcinoma	7/792	63/8135	0.4161	0.804	0.7402	GLI2/WNT3/FZD2/AXIN1/FZD4/WNT9B/FZD10	7
KEGG	hsa00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	3/792	24/8135	0.4182	0.804	0.7402	B3GAT3/HS3ST1/XYLT1	3
KEGG	hsa05415	Diabetic cardiomyopathy	21/792	203/8135	0.4183	0.804	0.7402	COX7B/ATP2A3/TGFB3/MAPK12/UQCRC1/RAC2/PDK4/CYC1/GYS1/UQCRH/TGFB1/CYBB/NDUFA4L2/AKT1/GAPDH/UQCRQ/SLC25A5/COX6B2/COX7C/RAC1/NDUFV1	21
KEGG	hsa04974	Protein digestion and absorption	11/792	103/8135	0.4204	0.804	0.7402	COL6A1/COL15A1/SLC1A1/SLC3A1/COL6A6/COL27A1/DPP4/COL6A2/COL4A3/COL9A2/COL24A1	11
KEGG	hsa04921	Oxytocin signaling pathway	16/792	154/8135	0.431	0.8097	0.7455	CACNB3/FOS/CAMK1/CALM3/ITPR3/PRKAB2/CACNA2D3/MAP2K5/ELK1/RYR3/MAP2K1/MAPK3/ADCY3/PRKACA/CACNG3/PPP1R12C	16
KEGG	hsa00190	Oxidative phosphorylation	14/792	134/8135	0.4321	0.8097	0.7455	COX7B/UQCRC1/CYC1/UQCRH/NDUFA4L2/ATP6V0C/UQCRQ/ATP6V0D1/COX6B2/COX7C/ATP6V0E1/ATP6V1B1/ATP6V1A/NDUFV1	14
KEGG	hsa04611	Platelet activation	13/792	124/8135	0.4326	0.8097	0.7455	ARHGEF1/MAPK12/VAMP8/ITPR3/FERMT3/ORAI1/ITGA2B/ITGB3/AKT1/MAPK3/ADCY3/PRKACA/GP9	13
KEGG	hsa04064	NF-kappa B signaling pathway	11/792	104/8135	0.4333	0.8097	0.7455	LY96/TNFRSF11A/LCK/CXCL12/XIAP/CD40LG/TNFRSF1A/CD14/CHUK/TRADD/MYD88	11
KEGG	hsa04726	Serotonergic synapse	12/792	115/8135	0.4453	0.824	0.7586	GNB3/GNG12/KCND2/ITPR3/APP/GNG10/GNB4/CASP3/MAP2K1/MAPK3/PRKACA/TPH1	12
KEGG	hsa04012	ErbB signaling pathway	9/792	85/8135	0.4479	0.824	0.7586	EIF4EBP1/AKT1/CRK/ELK1/MAP2K1/MAPK3/BTC/MYC/GRB2	9
KEGG	hsa04918	Thyroid hormone synthesis	8/792	75/8135	0.4485	0.824	0.7586	HSPA5/ITPR3/PAX8/GPX3/ATF4/CREB3L4/ADCY3/PRKACA	8
KEGG	hsa04310	Wnt signaling pathway	17/792	167/8135	0.4611	0.8408	0.7741	RAC2/RSPO3/WNT3/SFRP5/FZD2/AXIN1/TLE2/FZD4/SFRP2/CHD8/WNT9B/RAC1/TBL1X/PRICKLE2/FZD10/MYC/PRKACA	17
KEGG	hsa04810	Regulation of actin cytoskeleton	22/792	218/8135	0.4628	0.8408	0.7741	MRAS/ARHGEF1/RAC2/ITGA5/GNG12/SCIN/ACTN1/ITGA2B/IQGAP1/MYH10/ITGB3/CXCL12/PIP4K2C/CRK/ARPC4/RAC1/MAP2K1/MAPK3/NCKAP1/LIMK2/BCAR1/PPP1R12C	22
KEGG	hsa04340	Hedgehog signaling pathway	6/792	56/8135	0.467	0.8437	0.7768	CSNK1D/GLI2/IQCE/DISP1/PRKACA/BOC	6
KEGG	hsa00500	Starch and sucrose metabolism	4/792	36/8135	0.4702	0.8447	0.7777	PYGB/PGM1/G6PC3/GYS1	4
KEGG	hsa05100	Bacterial invasion of epithelial cells	8/792	77/8135	0.4788	0.8475	0.7803	ITGA5/RHOG/CRK/ARHGAP10/ARPC4/RAC1/BCAR1/CLTB	8
KEGG	hsa00230	Purine metabolism	13/792	128/8135	0.4797	0.8475	0.7803	PGM1/RRM2B/AMPD2/PFAS/RRM2/IMPDH2/ENTPD8/AK5/ENTPD4/ALLC/ADCY3/ATIC/ADK	13
KEGG	hsa04015	Rap1 signaling pathway	21/792	210/8135	0.4828	0.8475	0.7803	SIPA1L2/MRAS/ARAP3/MAPK12/RAC2/KITLG/CALM3/TEK/SIPA1L3/ITGA2B/ITGB3/AKT1/CRK/EPHA2/MAP2K3/RAC1/MAP2K1/MAPK3/ADCY3/BCAR1/NGF	21
KEGG	hsa01212	Fatty acid metabolism	6/792	57/8135	0.4846	0.8475	0.7803	ELOVL4/ACOX3/ACADSB/HADHB/ACADL/ACADS	6
KEGG	hsa04931	Insulin resistance	11/792	108/8135	0.4847	0.8475	0.7803	PYGB/G6PC3/NR1H3/GYS1/PRKAB2/OGT/AKT1/PTPN1/TNFRSF1A/PTPRF/CREB3L4	11
KEGG	hsa00980	Metabolism of xenobiotics by cytochrome P450	8/792	78/8135	0.4938	0.8504	0.7829	GSTT2/GSTT2B/CYP1B1/MGST3/GSTM5/CYP2E1/UGT1A3/DHDH	8
KEGG	hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	3/792	27/8135	0.497	0.8504	0.7829	B4GALT1/ST3GAL4/FUT4	3
KEGG	hsa04066	HIF-1 signaling pathway	11/792	109/8135	0.4974	0.8504	0.7829	EIF4EBP1/TEK/ENO1/CYBB/HMOX1/AKT1/GAPDH/MAP2K1/MAPK3/PFKFB3/EDN1	11
KEGG	hsa00120	Primary bile acid biosynthesis	2/792	17/8135	0.5035	0.8504	0.7829	AKR1C4/CYP27A1	2
KEGG	hsa04211	Longevity regulating pathway	9/792	89/8135	0.5045	0.8504	0.7829	EIF4EBP1/PRKAB2/RB1CC1/AKT1/ULK1/ATF4/CREB3L4/ADCY3/PRKACA	9
KEGG	hsa04727	GABAergic synapse	9/792	89/8135	0.5045	0.8504	0.7829	GNB3/GNG12/SLC38A5/GNG10/GNB4/SLC38A1/GABRR1/ADCY3/PRKACA	9
KEGG	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	9/792	89/8135	0.5045	0.8504	0.7829	MAPK12/FOS/LCK/AKT1/MAP2K3/MAP2K1/MAPK3/CHUK/MYD88	9
KEGG	hsa04920	Adipocytokine signaling pathway	7/792	69/8135	0.5135	0.8524	0.7848	G6PC3/PRKAB2/AKT1/RXRB/TNFRSF1A/CHUK/TRADD	7
KEGG	hsa05031	Amphetamine addiction	7/792	69/8135	0.5135	0.8524	0.7848	FOSB/FOS/CALM3/ARC/ATF4/CREB3L4/PRKACA	7
KEGG	hsa05340	Primary immunodeficiency	4/792	38/8135	0.5136	0.8524	0.7848	LCK/ORAI1/CD40LG/RFXANK	4
KEGG	hsa04919	Thyroid hormone signaling pathway	12/792	121/8135	0.5183	0.8531	0.7854	MED16/ATP2A3/NOTCH4/MED24/ITGB3/AKT1/RXRB/GATA4/MAP2K1/MAPK3/MYC/PRKACA	12
KEGG	hsa04330	Notch signaling pathway	6/792	59/8135	0.5192	0.8531	0.7854	DTX3/PSEN2/NOTCH4/TLE2/CIR1/DLL3	6
KEGG	hsa04672	Intestinal immune network for IgA production	5/792	49/8135	0.526	0.86	0.7918	HLA-DRA/TGFB1/CXCL12/CD40LG/HLA-DOB	5
KEGG	hsa04917	Prolactin signaling pathway	7/792	70/8135	0.5293	0.8611	0.7927	MAPK12/FOS/TNFRSF11A/AKT1/MAP2K1/MAPK3/GRB2	7
KEGG	hsa04979	Cholesterol metabolism	5/792	50/8135	0.5445	0.8814	0.8115	CYP27A1/LRP1/TSPO/STARD3/NPC2	5
KEGG	hsa00531	Glycosaminoglycan degradation	2/792	19/8135	0.5648	0.9042	0.8324	GNS/IDS	2
KEGG	hsa04660	T cell receptor signaling pathway	10/792	104/8135	0.5657	0.9042	0.8324	MAPK12/FOS/LCK/AKT1/CDK4/CD40LG/MAP2K1/MAPK3/GRB2/CHUK	10
KEGG	hsa01200	Carbon metabolism	11/792	115/8135	0.5715	0.9042	0.8324	MCEE/IDH3B/PGD/ACOX3/TPI1/TKT/GOT2/ENO1/GAPDH/ACADS/IDH2	11
KEGG	hsa04115	p53 signaling pathway	7/792	73/8135	0.5752	0.9042	0.8324	CDKN2A/RRM2B/RRM2/CDK4/GTSE1/CASP3/AIFM2	7
KEGG	hsa04216	Ferroptosis	4/792	41/8135	0.5753	0.9042	0.8324	CYBB/HMOX1/PCBP2/GCLM	4
KEGG	hsa00310	Lysine degradation	6/792	63/8135	0.5854	0.9042	0.8324	PLOD3/PRDM6/SETD2/ALDH3A2/NSD1/SETD1A	6
KEGG	hsa05171	Coronavirus disease - COVID-19	22/792	232/8135	0.5859	0.9042	0.8324	MAPK12/FOS/CYBB/RPL18/RPL23/RPL13/IRF3/MASP1/TNFRSF1A/RPS5/RPS28/C1S/MAPK3/RPL35/RPL28/CHUK/RPL23A/RPS7/MYD88/IKBKE/RPL9/RPL36	22
KEGG	hsa05152	Tuberculosis	17/792	180/8135	0.5907	0.9042	0.8324	TGFB3/MAPK12/CALM3/HLA-DRA/TGFB1/AKT1/ATP6V0C/ATP6V0D1/TNFRSF1A/CD14/CASP3/MAPK3/RAB5B/RFXANK/HLA-DOB/TRADD/MYD88	17
KEGG	hsa00052	Galactose metabolism	3/792	31/8135	0.5929	0.9042	0.8324	PGM1/B4GALT1/G6PC3	3
KEGG	hsa00410	beta-Alanine metabolism	3/792	31/8135	0.5929	0.9042	0.8324	ACOX3/ACADS/ALDH3A2	3
KEGG	hsa05310	Asthma	3/792	31/8135	0.5929	0.9042	0.8324	HLA-DRA/CD40LG/HLA-DOB	3
KEGG	hsa00100	Steroid biosynthesis	2/792	20/8135	0.5933	0.9042	0.8324	DHCR24/DHCR7	2
KEGG	hsa04610	Complement and coagulation cascades	8/792	85/8135	0.5945	0.9042	0.8324	CFH/F3/PROCR/CFI/MASP1/F12/C1S/TFPI	8
KEGG	hsa04929	GnRH secretion	6/792	64/8135	0.6012	0.9101	0.8379	GNA11/ITPR3/AKT1/MAP2K1/MAPK3/CACNA1H	6
KEGG	hsa05215	Prostate cancer	9/792	97/8135	0.6115	0.914	0.8415	RB1/AKT1/HSP90AB1/ATF4/MAP2K1/MAPK3/CREB3L4/GRB2/CHUK	9
KEGG	hsa00860	Porphyrin metabolism	4/792	43/8135	0.614	0.914	0.8415	BLVRB/FECH/HMOX1/UGT1A3	4
KEGG	hsa04659	Th17 cell differentiation	10/792	108/8135	0.6149	0.914	0.8415	MAPK12/FOS/HLA-DRA/TGFB1/LCK/RXRB/HSP90AB1/MAPK3/HLA-DOB/CHUK	10
KEGG	hsa00640	Propanoate metabolism	3/792	32/8135	0.6149	0.914	0.8415	MCEE/ACOX3/ACADS	3
KEGG	hsa00770	Pantothenate and CoA biosynthesis	2/792	21/8135	0.6204	0.918	0.8451	BCAT2/ALDH3A2	2
KEGG	hsa05231	Choline metabolism in cancer	9/792	98/8135	0.6241	0.9192	0.8463	RAC2/FOS/EIF4EBP1/AKT1/PLD2/RAC1/MAP2K1/MAPK3/GRB2	9
KEGG	hsa04621	NOD-like receptor signaling pathway	17/792	184/8135	0.6281	0.921	0.8479	TRPV2/MAPK12/TXNIP/ANTXR2/BRCC3/ITPR3/CYBB/ANTXR1/XIAP/IRF3/AIM2/HSP90AB1/MAPK3/TXN/CHUK/MYD88/IKBKE	17
KEGG	hsa04114	Oocyte meiosis	12/792	131/8135	0.6324	0.9232	0.85	PKMYT1/MAPK12/CALM3/CPEB1/ITPR3/ANAPC5/PPP2R1A/MAP2K1/MAPK3/ADCY3/PRKACA/PPP2R5D	12
KEGG	hsa04130	SNARE interactions in vesicular transport	3/792	33/8135	0.6362	0.9246	0.8512	VAMP8/SEC22B/SNAP29	3
KEGG	hsa00920	Sulfur metabolism	1/792	10/8135	0.6412	0.9246	0.8512	MPST	1
KEGG	hsa00010	Glycolysis / Gluconeogenesis	6/792	67/8135	0.6465	0.9246	0.8512	PGM1/G6PC3/TPI1/ENO1/GAPDH/ALDH3A2	6
KEGG	hsa04720	Long-term potentiation	6/792	67/8135	0.6465	0.9246	0.8512	CALM3/ITPR3/ATF4/MAP2K1/MAPK3/PRKACA	6
KEGG	hsa02010	ABC transporters	4/792	45/8135	0.6503	0.9246	0.8512	ABCA3/ABCA2/ABCB9/ABCC11	4
KEGG	hsa03022	Basal transcription factors	4/792	45/8135	0.6503	0.9246	0.8512	TAF9/GTF2H4/ERCC3/TAF1L	4
KEGG	hsa03020	RNA polymerase	3/792	34/8135	0.6566	0.9272	0.8537	POLR2E/POLR2J/POLR2A	3
KEGG	hsa04270	Vascular smooth muscle contraction	12/792	134/8135	0.6638	0.9272	0.8537	ARHGEF1/GNA11/CALM3/ITPR3/MYH10/ADM2/MAP2K1/MAPK3/ADCY3/PRKACA/EDN1/PPP1R12C	12
KEGG	hsa03430	Mismatch repair	2/792	23/8135	0.6704	0.9272	0.8537	POLD1/POLD2	2
KEGG	hsa04614	Renin-angiotensin system	2/792	23/8135	0.6704	0.9272	0.8537	THOP1/PREP	2
KEGG	hsa05032	Morphine addiction	8/792	91/8135	0.6722	0.9272	0.8537	GNB3/GNG12/GRK5/GNG10/GNB4/GABRR1/ADCY3/PRKACA	8
KEGG	hsa04924	Renin secretion	6/792	69/8135	0.675	0.9272	0.8537	CALM3/ITPR3/ORAI1/CLCA4/PRKACA/EDN1	6
KEGG	hsa00130	Ubiquinone and other terpenoid-quinone biosynthesis	1/792	11/8135	0.6761	0.9272	0.8537	VKORC1	1
KEGG	hsa04658	Th1 and Th2 cell differentiation	8/792	92/8135	0.6842	0.9272	0.8537	MAPK12/FOS/HLA-DRA/LCK/DLL3/MAPK3/HLA-DOB/CHUK	8
KEGG	hsa04530	Tight junction	15/792	169/8135	0.6867	0.9272	0.8537	ACTN1/PRKAB2/TUBA3C/PPP2R2A/MYH10/TJP2/TUBA1C/TUBA4A/CDK4/MPDZ/GATA4/PPP2R1A/ARPC4/RAC1/PRKACA	15
KEGG	hsa04622	RIG-I-like receptor signaling pathway	6/792	70/8135	0.6886	0.9272	0.8537	MAPK12/PIN1/IRF3/CHUK/TRADD/IKBKE	6
KEGG	hsa05230	Central carbon metabolism in cancer	6/792	70/8135	0.6886	0.9272	0.8537	SLC7A5/AKT1/MAP2K1/MAPK3/IDH2/MYC	6
KEGG	hsa04625	C-type lectin receptor signaling pathway	9/792	104/8135	0.6946	0.9272	0.8537	MRAS/MAPK12/CALM3/ITPR3/AKT1/IL17D/MAPK3/CHUK/IKBKE	9
KEGG	hsa00760	Nicotinate and nicotinamide metabolism	3/792	36/8135	0.6949	0.9272	0.8537	SIRT2/NNT/SIRT4	3
KEGG	hsa04146	Peroxisome	7/792	82/8135	0.6983	0.9272	0.8537	ACOX3/PECR/PEX14/MVK/PHYH/PRDX5/IDH2	7
KEGG	hsa04730	Long-term depression	5/792	60/8135	0.7074	0.9272	0.8537	GNA11/ITPR3/PPP2R1A/MAP2K1/MAPK3	5
KEGG	hsa05162	Measles	12/792	139/8135	0.7127	0.9272	0.8537	FOS/HSPA2/AKT1/RAB9B/CDK4/IRF3/EIF2S1/CASP3/CHUK/TRADD/MYD88/IKBKE	12
KEGG	hsa04960	Aldosterone-regulated sodium reabsorption	3/792	37/8135	0.7128	0.9272	0.8537	NR3C2/SLC9A3R2/MAPK3	3
KEGG	hsa05143	African trypanosomiasis	3/792	37/8135	0.7128	0.9272	0.8537	LAMA4/THOP1/MYD88	3
KEGG	hsa00982	Drug metabolism - cytochrome P450	6/792	72/8135	0.7148	0.9272	0.8537	GSTT2/GSTT2B/MGST3/GSTM5/CYP2E1/UGT1A3	6
KEGG	hsa05218	Melanoma	6/792	72/8135	0.7148	0.9272	0.8537	RB1/CDKN2A/AKT1/CDK4/MAP2K1/MAPK3	6
KEGG	hsa05030	Cocaine addiction	4/792	49/8135	0.716	0.9272	0.8537	FOSB/ATF4/CREB3L4/PRKACA	4
KEGG	hsa00562	Inositol phosphate metabolism	6/792	73/8135	0.7273	0.9272	0.8537	PI4KB/INPP5E/INPPL1/PLCH2/TPI1/PIP4K2C	6
KEGG	hsa05150	Staphylococcus aureus infection	8/792	96/8135	0.7296	0.9272	0.8537	CFH/HLA-DRA/CFI/MASP1/KRT9/C1S/HLA-DOB/KRT24	8
KEGG	hsa00510	N-Glycan biosynthesis	4/792	50/8135	0.7309	0.9272	0.8537	B4GALT1/RPN2/ALG3/ALG10B	4
KEGG	hsa04213	Longevity regulating pathway - multiple species	5/792	62/8135	0.7345	0.9272	0.8537	HSPA2/PRKAB2/AKT1/ADCY3/PRKACA	5
KEGG	hsa00563	Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	2/792	26/8135	0.7352	0.9272	0.8537	PIGZ/PIGX	2
KEGG	hsa00790	Folate biosynthesis	2/792	26/8135	0.7352	0.9272	0.8537	AKR1C3/TPH1	2
KEGG	hsa03450	Non-homologous end-joining	1/792	13/8135	0.7362	0.9272	0.8537	XRCC6	1
KEGG	hsa01240	Biosynthesis of cofactors	13/792	153/8135	0.7386	0.9272	0.8537	PDXP/FECH/BCAT2/MTHFD1L/GMPPA/MTHFD1/VKORC1/ALDH3A2/UGT1A3/AK5/MAT2B/UMPS/GCLM	13
KEGG	hsa04911	Insulin secretion	7/792	86/8135	0.7448	0.9272	0.8537	GNA11/ITPR3/GCG/ATF4/CREB3L4/ADCY3/PRKACA	7
KEGG	hsa00513	Various types of N-glycan biosynthesis	3/792	39/8135	0.7461	0.9272	0.8537	B4GALT1/RPN2/ALG3	3
KEGG	hsa04623	Cytosolic DNA-sensing pathway	5/792	63/8135	0.7474	0.9272	0.8537	POLR2E/IRF3/AIM2/CHUK/IKBKE	5
KEGG	hsa04750	Inflammatory mediator regulation of TRP channels	8/792	98/8135	0.7505	0.9272	0.8537	TRPV2/MAPK12/CALM3/ITPR3/MAP2K3/ADCY3/PRKACA/NGF	8
KEGG	hsa04024	cAMP signaling pathway	19/792	221/8135	0.7513	0.9272	0.8537	ARAP3/ATP2A3/RAC2/FOS/ACOX3/CALM3/GCG/ORAI1/AKT1/PLD2/PTGER3/SSTR2/RAC1/MAP2K1/MAPK3/CREB3L4/ADCY3/PRKACA/EDN1	19
KEGG	hsa00062	Fatty acid elongation	2/792	27/8135	0.7543	0.9272	0.8537	ELOVL4/HADHB	2
KEGG	hsa01040	Biosynthesis of unsaturated fatty acids	2/792	27/8135	0.7543	0.9272	0.8537	ELOVL4/ACOX3	2
KEGG	hsa04971	Gastric acid secretion	6/792	76/8135	0.7625	0.9338	0.8597	CALM3/ITPR3/SSTR2/ADCY3/PRKACA/SLC4A2	6
KEGG	hsa04961	Endocrine and other factor-regulated calcium reabsorption	4/792	53/8135	0.7721	0.9338	0.8597	AP2A2/AP2S1/PRKACA/CLTB	4
KEGG	hsa00650	Butanoate metabolism	2/792	28/8135	0.7721	0.9338	0.8597	L2HGDH/ACADS	2
KEGG	hsa00970	Aminoacyl-tRNA biosynthesis	5/792	66/8135	0.7832	0.9338	0.8597	SARS2/FARS2/FARSA/PARS2/TARS2	5
KEGG	hsa00604	Glycosphingolipid biosynthesis - ganglio series	1/792	15/8135	0.7852	0.9338	0.8597	ST3GAL2	1
KEGG	hsa00730	Thiamine metabolism	1/792	15/8135	0.7852	0.9338	0.8597	AK5	1
KEGG	hsa04723	Retrograde endocannabinoid signaling	12/792	148/8135	0.7887	0.9338	0.8597	MAPK12/GNB3/GNG12/ITPR3/NDUFA4L2/GNG10/GNB4/GABRR1/NDUFV1/MAPK3/ADCY3/PRKACA	12
KEGG	hsa04392	Hippo signaling pathway - multiple species	2/792	29/8135	0.7888	0.9338	0.8597	FRMD6/STK3	2
KEGG	hsa04744	Phototransduction	2/792	29/8135	0.7888	0.9338	0.8597	CALM3/GRK7	2
KEGG	hsa00380	Tryptophan metabolism	3/792	42/8135	0.7902	0.9338	0.8597	CYP1B1/ALDH3A2/TPH1	3
KEGG	hsa01521	EGFR tyrosine kinase inhibitor resistance	6/792	79/8135	0.7942	0.9338	0.8597	EIF4EBP1/GAS6/AKT1/MAP2K1/MAPK3/GRB2	6
KEGG	hsa00020	Citrate cycle (TCA cycle)	2/792	30/8135	0.8045	0.9338	0.8597	IDH3B/IDH2	2
KEGG	hsa00053	Ascorbate and aldarate metabolism	2/792	30/8135	0.8045	0.9338	0.8597	ALDH3A2/UGT1A3	2
KEGG	hsa00630	Glyoxylate and dicarboxylate metabolism	2/792	30/8135	0.8045	0.9338	0.8597	MCEE/HYI	2
KEGG	hsa00830	Retinol metabolism	5/792	68/8135	0.8048	0.9338	0.8597	RDH5/DHRS4L2/CYP3A7/DGAT1/UGT1A3	5
KEGG	hsa00360	Phenylalanine metabolism	1/792	16/8135	0.8061	0.9338	0.8597	GOT2	1
KEGG	hsa04923	Regulation of lipolysis in adipocytes	4/792	56/8135	0.8081	0.9338	0.8597	AKT1/PTGER3/ADCY3/PRKACA	4
KEGG	hsa05034	Alcoholism	15/792	187/8135	0.8215	0.9459	0.8708	FOSB/GNB3/GNG12/CALM3/GNG10/GNB4/PKIA/ATF4/MAP2K1/MAPK3/CREB3L4/PRKACA/GRB2/SLC29A1/NTRK2	15
KEGG	hsa04120	Ubiquitin mediated proteolysis	11/792	142/8135	0.8282	0.9503	0.8749	UBE2O/CUL4A/HERC4/STUB1/UBE2F/PIAS2/XIAP/TRIM32/ANAPC5/FBXO4/CDC34	11
KEGG	hsa04136	Autophagy - other	2/792	32/8135	0.8327	0.952	0.8765	MLST8/ATG2A	2
KEGG	hsa04022	cGMP-PKG signaling pathway	13/792	167/8135	0.8395	0.9541	0.8784	ATP2A3/GNA11/CALM3/ITPR3/AKT1/SLC25A5/GATA4/ATF4/MAP2K1/MAPK3/CREB3L4/ADCY3/KCNJ8	13
KEGG	hsa00511	Other glycan degradation	1/792	18/8135	0.8421	0.9541	0.8784	MAN2B2	1
KEGG	hsa04070	Phosphatidylinositol signaling system	7/792	97/8135	0.8458	0.9541	0.8784	PI4KB/INPP5E/INPPL1/CALM3/ITPR3/IP6K1/PIP4K2C	7
KEGG	hsa04978	Mineral absorption	4/792	60/8135	0.8489	0.9541	0.8784	ATP7B/STEAP2/HMOX1/ATOX1	4
KEGG	hsa04973	Carbohydrate digestion and absorption	3/792	47/8135	0.8495	0.9541	0.8784	G6PC3/SLC2A5/AKT1	3
KEGG	hsa00564	Glycerophospholipid metabolism	7/792	98/8135	0.8532	0.9541	0.8784	PNPLA6/PTDSS1/PTDSS2/PLD2/LPCAT4/MBOAT2/GPD1	7
KEGG	hsa00040	Pentose and glucuronate interconversions	2/792	34/8135	0.8571	0.9541	0.8784	UGT1A3/DHDH	2
KEGG	hsa00590	Arachidonic acid metabolism	4/792	61/8135	0.8578	0.9541	0.8784	AKR1C3/PTGES2/GPX3/CYP2E1	4
KEGG	hsa03320	PPAR signaling pathway	5/792	75/8135	0.8672	0.9598	0.8836	NR1H3/ACOX3/CYP27A1/ACADL/RXRB	5
KEGG	hsa00565	Ether lipid metabolism	3/792	49/8135	0.8688	0.9598	0.8836	PAFAH1B1/PLD2/LPCAT4	3
KEGG	hsa04670	Leukocyte transendothelial migration	8/792	114/8135	0.8776	0.9621	0.8858	MAPK12/RAC2/ACTN1/CYBB/CXCL12/RAC1/BCAR1/THY1	8
KEGG	hsa00350	Tyrosine metabolism	2/792	36/8135	0.8783	0.9621	0.8858	GOT2/HGD	2
KEGG	hsa04972	Pancreatic secretion	7/792	102/8135	0.8797	0.9621	0.8858	ATP2A3/TPCN2/ITPR3/CLCA4/RAC1/ADCY3/SLC4A2	7
KEGG	hsa00250	Alanine, aspartate and glutamate metabolism	2/792	37/8135	0.8878	0.9661	0.8894	GOT2/ASL	2
KEGG	hsa05321	Inflammatory bowel disease	4/792	65/8135	0.8892	0.9661	0.8894	TGFB3/HLA-DRA/TGFB1/HLA-DOB	4
KEGG	hsa00340	Histidine metabolism	1/792	22/8135	0.8953	0.9694	0.8925	ALDH3A2	1
KEGG	hsa04970	Salivary secretion	6/792	93/8135	0.9008	0.9722	0.8951	CALM3/ITPR3/RYR3/ADCY3/PRKACA/SLC4A2	6
KEGG	hsa05206	MicroRNAs in cancer	24/792	310/8135	0.9074	0.9732	0.896	CDKN2A/ZEB2/CYP1B1/ITGA5/WNT3/ZFPM2/DDIT4/NOTCH4/MIR7-3/HMOX1/ITGB3/PDCD4/MIRLET7C/SPRY2/CRK/CASP3/SLC45A3/MIR9-3/MAP2K1/MAPK3/MARCKS/MIR9-1/MYC/GRB2	24
KEGG	hsa05202	Transcriptional misregulation in cancer	14/792	193/8135	0.9077	0.9732	0.896	ZBTB17/DDIT3/TSPAN7/PAX8/ETV6/MEN1/CCNA2/RXRB/CD14/SS18/SLC45A3/EWSR1/MYC/FUS	14
KEGG	hsa00592	alpha-Linolenic acid metabolism	1/792	25/8135	0.9231	0.9815	0.9036	ACOX3	1
KEGG	hsa05131	Shigellosis	18/792	247/8135	0.928	0.9815	0.9036	MAPK12/ITGA5/TECPR1/ITPR3/ACTN1/AKT1/IRF3/CRK/TNFRSF1A/CD14/RRAGB/ARPC4/RAC1/MAPK3/BCAR1/CHUK/TRADD/MYD88	18
KEGG	hsa04137	Mitophagy - animal	4/792	72/8135	0.9298	0.9815	0.9036	MRAS/RHOT2/ULK1/ATF4	4
KEGG	hsa04060	Cytokine-cytokine receptor interaction	22/792	295/8135	0.9301	0.9815	0.9036	TGFB3/TNFRSF12A/IL1RL1/TNFRSF11A/TNFSF10/TGFB1/IL20RB/IL17D/CXCL12/ACVR1C/CD40LG/TNFRSF1A/GDF10/BMP7/PPBP/INHBC/IL3RA/BMP6/CTF1/CXCR3/ACVR1/NGF	22
KEGG	hsa04975	Fat digestion and absorption	2/792	43/8135	0.9316	0.9815	0.9036	GOT2/DGAT1	2
KEGG	hsa04061	Viral protein interaction with cytokine and cytokine receptor	6/792	100/8135	0.9334	0.9815	0.9036	TNFSF10/IL20RB/CXCL12/TNFRSF1A/PPBP/CXCR3	6
KEGG	hsa04020	Calcium signaling pathway	17/792	240/8135	0.9408	0.9839	0.9058	ATP2A3/GNA11/CAMK1/CALM3/TPCN2/ITPR3/ORAI1/PHKG2/PTGER3/SLC25A5/TRDN/RYR3/ADCY3/PRKACA/NTRK2/CACNA1H/NGF	17
KEGG	hsa04976	Bile secretion	5/792	89/8135	0.9428	0.9839	0.9058	UGT1A3/AQP8/ADCY3/PRKACA/SLC4A2	5
KEGG	hsa00561	Glycerolipid metabolism	3/792	61/8135	0.9448	0.9839	0.9058	DGAT1/ALDH3A2/MBOAT2	3
KEGG	hsa00591	Linoleic acid metabolism	1/792	29/8135	0.949	0.9851	0.907	CYP2E1	1
KEGG	hsa04217	Necroptosis	10/792	159/8135	0.9542	0.9874	0.9091	PYGB/TNFSF10/CYBB/XIAP/MLKL/HSP90AB1/SLC25A5/TNFRSF1A/CHMP6/TRADD	10
KEGG	hsa04072	Phospholipase D signaling pathway	8/792	148/8135	0.9806	0.9996	0.9202	MRAS/KITLG/AKT1/PLD2/MAP2K1/MAPK3/ADCY3/GRB2	8
KEGG	hsa00260	Glycine, serine and threonine metabolism	1/792	40/8135	0.9836	0.9996	0.9202	BHMT	1
KEGG	hsa05033	Nicotine addiction	1/792	40/8135	0.9836	0.9996	0.9202	GABRR1	1
KEGG	hsa04930	Type II diabetes mellitus	1/792	46/8135	0.9911	0.9996	0.9202	MAPK3	1
KEGG	hsa04613	Neutrophil extracellular trap formation	10/792	190/8135	0.9917	0.9996	0.9202	MAPK12/RAC2/CYBB/ITGA2B/ITGB3/AKT1/SLC25A5/RAC1/MAP2K1/MAPK3	10
KEGG	hsa04630	JAK-STAT signaling pathway	8/792	162/8135	0.9918	0.9996	0.9202	PIAS2/IL20RB/AKT1/IL17D/IL3RA/CTF1/MYC/GRB2	8
KEGG	hsa00620	Pyruvate metabolism	1/792	47/8135	0.992	0.9996	0.9202	ALDH3A2	1
KEGG	hsa04742	Taste transduction	3/792	86/8135	0.9923	0.9996	0.9202	GNB3/ITPR3/PRKACA	3
KEGG	hsa05322	Systemic lupus erythematosus	6/792	136/8135	0.9934	0.9996	0.9202	HLA-DRA/ACTN1/CD40LG/SNRPD3/C1S/HLA-DOB	6
KEGG	hsa04740	Olfactory transduction	16/792	440/8135	1	1	0.9207	OR4D11/OR5J2/CALM3/OR3A1/OR2H2/OR6P1/OR2A42/OR2T4/OR52I1/OR52E5/OR14J1/OR10H1/OR56B4/ADCY3/OR5AC2/PRKACA	16
KEGG	hsa04080	Neuroactive ligand-receptor interaction	10/792	353/8135	1	1	0.9207	GCG/ADM2/TSPO/PTGER3/NMB/DRD4/SSTR2/GABRR1/GAL/EDN1	10