ONTOLOGY	ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	qvalue	geneID	Count
BP	GO:0001819	positive regulation of cytokine production	126/2619	464/18670	4.71e-14	2.964e-10	2.223e-10	AIM2/RNF125/SPHK1/TREM2/CD200/STAT1/IRF1/BIRC3/JAK2/PRKD2/RASGRP1/IL27RA/MAPK3/RIPK2/PLCG2/AGPAT1/TBK1/CLU/LRRFIP1/MALT1/SMAD3/IL15/HLA-F/RORA/HLA-G/IL4R/LILRB2/PTPRC/POLR2L/HGF/ADAM17/LILRA2/POLR3C/POLR2E/POLR2F/NLRP1/IDO1/PUM2/SERPINE1/CARD8/TNFRSF14/CD83/BIRC2/HLA-E/TSPAN6/HTR2B/WNT11/ARHGEF2/IRF3/PTPN22/CD28/IL1RL2/CRTAM/FGR/CD40/PTGER4/ELANE/F2R/HSPB1/CD81/NFKB1/PELI1/POSTN/CD3E/TUSC2/IFNG/AGT/MAPK11/CHUK/LY9/IL6/EGR1/TLR5/GPATCH3/TXK/EREG/TYROBP/XCL1/SLC11A1/MMP12/IL17RB/TNFSF4/HMGB1/GLMN/CCR7/PRKCQ/NOD2/FERMT1/MAPKAPK2/CD58/SOD1/LPL/DDX1/HIF1A/TMF1/IL17RC/DDX60/SETD2/IL1RN/IFI16/CD2/DDX21/GSDMD/NOD1/IL6R/SEC14L1/CEBPG/CREB1/FCN1/DDX41/BCL10/ATF2/EP300/TRIM32/XBP1/MYD88/POLR1C/RIOK3/TLR8/CCR2/CEBPB/CD40LG/ATF4/IL17RA/DDIT3/TWIST1	126
BP	GO:0042110	T cell activation	121/2619	464/18670	3.087e-12	9.713e-09	7.285e-09	LCP1/IRF1/TNFRSF1B/SOCS6/CCL5/BTN2A2/RASGRP1/TFRC/IGFBP2/RIPK2/ELF4/MALT1/SMAD3/IL15/RORA/HLA-G/MICB/IL7R/RAB27A/PLA2G2D/SEMA4A/IL4R/LILRB2/PTPRC/SOS1/CD8A/TCF7/GPR183/ITK/ADAM17/BAD/HSPH1/TNFRSF21/CTLA4/ITGAL/IDO1/PRNP/NCK2/ADA/RUNX3/TNFRSF14/CD83/HLA-E/SOCS1/KIT/HFE/BCL11B/LAX1/BMP4/ERBB2/LEF1/PTPN22/CD28/IL1RL2/PTGER4/JMJD6/PTPN2/TCIRG1/RC3H2/CD44/ZAP70/MAP3K8/PNP/CD81/PELI1/CD3E/CR1/CD27/RELB/IFNG/LCK/IGF1/LY9/EFNB1/RAC2/CD3D/IL6/EGR1/CD151/CD7/XCL1/PRDM1/SLC11A1/SATB1/TNFSF4/HMGB1/GLMN/CCR7/PRKCQ/NOD2/BATF/PPP3CA/DDOST/ZFP36L2/SOD1/LAT/TNFSF8/JAG2/PRDX2/BTN3A1/CYLD/CD2/CTPS1/PIK3CD/IL6R/TNFSF14/RHOH/VNN1/PAK2/LGALS3/BCL10/CXADR/PATZ1/XBP1/CD3G/FZD7/CCR2/CEBPB/CD40LG/STOML2/PIK3CA	121
BP	GO:0030098	lymphocyte differentiation	97/2619	353/18670	1.927e-11	4.042e-08	3.032e-08	SLAMF8/SFRP1/IRF1/BTN2A2/DCLRE1C/RASGRP1/RIPK2/PLCG2/MALT1/IL15/RORA/HLA-G/IL7R/PLA2G2D/SEMA4A/IL4R/LILRB2/PTPRC/SOS1/CD8A/TCF7/GPR183/ITK/ADAM17/ATM/BAD/CTLA4/DOCK10/MERTK/TPD52/ADA/RUNX3/GON4L/CD83/SOCS1/KIT/BCL11B/BMP4/ERBB2/LEF1/PTPN22/CD28/IL1RL2/TOX/PTGER4/JMJD6/PTPN2/KLF6/TCIRG1/RC3H2/ZAP70/PNP/NTRK1/CD3E/TUSC2/CR1/CD27/RELB/IFNG/LCK/HMGB3/LY9/CD3D/IL6/EGR1/RBPJ/AXL/PRDM1/CD19/SATB1/TNFSF4/HMGB1/CCR7/BATF/ZFP36L2/SOD1/TNFSF8/JAG2/PRDX2/CYLD/CD2/PIK3CD/TCF3/CEBPG/ID2/RHOH/VNN1/TYRO3/PATZ1/EP300/XBP1/CD3G/MS4A1/PTK2B/FZD7/CCR2/CD40LG	97
BP	GO:0030217	T cell differentiation	72/2619	240/18670	1.081e-10	1.701e-07	1.276e-07	IRF1/BTN2A2/RASGRP1/RIPK2/MALT1/IL15/RORA/HLA-G/IL7R/PLA2G2D/SEMA4A/IL4R/LILRB2/PTPRC/SOS1/CD8A/TCF7/GPR183/ITK/ADAM17/BAD/CTLA4/ADA/RUNX3/CD83/SOCS1/KIT/BCL11B/BMP4/ERBB2/LEF1/PTPN22/CD28/IL1RL2/PTGER4/JMJD6/PTPN2/TCIRG1/RC3H2/ZAP70/PNP/CD3E/CR1/CD27/RELB/IFNG/LCK/LY9/CD3D/IL6/EGR1/PRDM1/SATB1/TNFSF4/HMGB1/CCR7/BATF/ZFP36L2/SOD1/TNFSF8/JAG2/PRDX2/CYLD/CD2/PIK3CD/RHOH/VNN1/PATZ1/XBP1/CD3G/FZD7/CCR2	72
BP	GO:0009123	nucleoside monophosphate metabolic process	96/2619	375/18670	1.568e-09	1.486e-06	1.114e-06	NUPR1/ATP1B1/TREM2/COX7A1/TK2/ENPP1/NDUFC1/SNCA/SDHC/NDUFA13/NDUFS4/NUP160/CBFA2T3/DDIT4/PID1/IMPDH2/NT5C2/BAD/NUP153/NDUFB4/ADK/PGM1/PINK1/NDUFA4/ADA/UQCR10/NDUFA8/INSR/TPR/PRKAG1/ENO2/NUP50/DGUOK/SLC2A6/NUDT9/CYC1/COX6C/SEC13/AK1/COX8A/RANBP2/PFKFB3/NDUFA2/TAZ/COX6A1/NDUFB6/PFKM/IFNG/NDUFB7/NUDT11/SDHD/AK6/DLD/TSPO/IGF1/CCNB1/NDUFB2/NDUFA6/GUK1/DCTD/NUP210/COX5B/NDUFA10/NDUFB11/RAD50/NCOR1/COQ9/NUP43/HIF1A/NDC1/OGT/NDUFB8/PRKAA1/DNPH1/MYH4/NDUFA3/UQCRQ/TYMS/MPP1/NDUFS3/CDK1/TJP2/ALDOC/NDUFS7/NT5E/EIF6/NDUFS6/PRPS1/PRPS2/STOML2/NDUFA1/UQCRC1/AMPD3/NUP98/ADPGK/NUP62	96
BP	GO:2000116	regulation of cysteine-type endopeptidase activity	69/2619	239/18670	1.627e-09	1.486e-06	1.114e-06	AIM2/MICAL1/FAM162A/LGMN/MAP3K5/BIRC3/DAP/JAK2/FIS1/RIPK2/SNCA/LAMP3/MALT1/SMAD3/FAS/HERPUD1/NDUFA13/CFLAR/CRADD/PSMB9/HGF/NLE1/BAD/NLRP1/CARD8/BIRC2/BIRC7/CASP4/TNFAIP8/NOL3/LEF1/USP47/ASPH/CYFIP2/PPARG/GPX1/GPER1/CRYAB/ARRB1/CD44/F2R/CD27/LCK/APAF1/MYC/PML/CASP9/VEGFA/CASP8AP2/HMGB1/MTCH1/DHCR24/EGLN3/BIRC5/CST7/ARL6IP5/NAIP/GRAMD4/CIDEB/IFI16/NOD1/NGFR/RAF1/TNFSF14/HIP1R/PAK2/BCL10/RPS6KA1/RNF34	69
BP	GO:0140014	mitotic nuclear division	74/2619	264/18670	1.795e-09	1.486e-06	1.114e-06	TOM1L1/SPHK1/TUBG2/NDE1/NIPBL/BTC/CHEK2/CHEK1/ATM/DLGAP5/KIF2A/EGF/TPX2/PTTG1/RACGAP1/MKI67/PRMT5/INSR/TPR/BMP4/BUB1B/NUSAP1/SPAG5/LCMT1/CD28/SMC5/CDC14A/NCAPH/CDCA8/CHMP6/KNTC1/KIF18B/DRG1/PRC1/NDC80/PHIP/CENPE/KIF11/LRP5/CTDP1/IGF1/CHMP2A/NAA50/CCNB1/NCAPG/MIS12/KIF4A/CDKN1C/CLASP1/CDC20/EREG/ATRX/PDGFB/AURKB/PIN1/BIRC5/KPNB1/NFE2L1/SMC4/SPAST/KATNB1/AKAP8/SMC1A/CHMP1B/TACC3/CENPC/SPICE1/FLNA/PTTG2/CENPF/SIRT7/NUP62/POGZ/FBXO5	74
BP	GO:0032496	response to lipopolysaccharide	87/2619	330/18670	1.978e-09	1.486e-06	1.114e-06	TNFAIP3/GCH1/CXCL9/NFKBIA/CSF2RB/CXCL10/NOTCH1/IRAK3/TREM2/TNFRSF1B/JAK2/CCL5/MAPK3/RIPK2/PLCG2/CXCL13/SNCA/MALT1/CXCL11/SLPI/TNIP2/LILRB2/ADAM17/LILRA2/TNIP3/IDO1/COMT/CX3CR1/SERPINE1/CARD8/TNFRSF11A/CDK4/HNRNPA0/CXCL2/CCR5/PENK/SELE/CD96/GNG12/TFPI/IRF3/PTPN22/HPGD/PTGER4/PTGFR/ELANE/F2R/NFKB1/PELI1/TRIB1/ASS1/CHUK/TSPO/NOS3/LDOC1/NR1H2/IL6/PLSCR4/GHSR/CPS1/AXL/SLC11A1/DEFA6/CASP9/MTDH/TNFSF4/HMGB1/TIMP4/CCR7/LY86/NOD2/CXCL3/MAPKAPK2/SGMS1/SRR/AKAP8/PRDX2/IL1RN/TAC1/CTSG/DEFA5/BCL10/XBP1/CXCL8/CEBPB/TH/SBNO2	87
BP	GO:0050852	T cell receptor signaling pathway	61/2619	202/18670	2.125e-09	1.486e-06	1.114e-06	GBP1/HLA-DRB4/PRKD2/BTN2A2/RIPK2/PLCG2/SKP1/MALT1/BTN2A1/PTPRC/PSMB9/RFTN1/ITK/TNFRSF21/CTLA4/PRNP/ADA/BTN3A3/PTPN22/PSMC2/CD28/DENND1B/PTPN2/RC3H2/ZAP70/CD81/NFKB1/TRBC1/CD3E/LCK/PSMB6/TRAT1/CHUK/PIK3CB/PSMC3/CD3D/TRAC/TXK/CD247/HLA-DQB1/PSMD8/CCR7/PRKCQ/THEMIS2/PSMB5/LAT/PSMD10/LIME1/BTN3A1/CYLD/ERMAP/PIK3CD/IKBKG/PAK2/LGALS3/BCL10/CD3G/LCP2/STOML2/BTNL2/PIK3CA	61
BP	GO:0009144	purine nucleoside triphosphate metabolic process	88/2619	342/18670	5.746e-09	3.382e-06	2.537e-06	NUPR1/ATP1B1/TREM2/NME4/COX7A1/ENPP1/NDUFC1/NME7/SNCA/SDHC/NDUFA13/NDUFS4/NUP160/CBFA2T3/DDIT4/PID1/IMPDH2/NME5/BAD/NUP153/NDUFB4/ADK/PGM1/PINK1/NDUFA4/ADA/UQCR10/NDUFA8/INSR/TPR/MOCS2/PRKAG1/SAMHD1/ENO2/NUP50/DGUOK/NME3/SLC2A6/CYC1/COX6C/SEC13/AK1/COX8A/RANBP2/PFKFB3/NDUFA2/TAZ/COX6A1/NDUFB6/PFKM/IFNG/NDUFB7/SDHD/DLD/TSPO/IGF1/CCNB1/NDUFB2/NDUFA6/GUK1/NUP210/COX5B/NDUFA10/NDUFB11/NCOR1/COQ9/NUP43/HIF1A/NDC1/OGT/NDUFB8/PRKAA1/MYH4/NDUFA3/UQCRQ/NDUFS3/CDK1/ALDOC/NDUFS7/EIF6/NDUFS6/STOML2/NDUFA1/UQCRC1/AMPD3/NUP98/ADPGK/NUP62	88
BP	GO:0007159	leukocyte cell-cell adhesion	87/2619	337/18670	5.912e-09	3.382e-06	2.537e-06	IRF1/SOCS6/CCL5/BTN2A2/RASGRP1/TFRC/SEMA4D/IGFBP2/RIPK2/MALT1/IL15/HLA-G/IL7R/TNIP1/STK10/PLA2G2D/IL4R/LILRB2/PTPRC/BAD/HSPH1/TNFRSF21/CTLA4/ITGAL/ITGA5/IDO1/PRNP/NCK2/CX3CR1/ADA/RUNX3/TNFRSF14/CD83/HLA-E/SOCS1/PECAM1/HFE/LAX1/BMP4/ERBB2/SELE/PTPN22/CD28/ROCK1/IL1RL2/ITGB7/PTPN2/RC3H2/CD44/ZAP70/ELANE/MAP3K8/PNP/CD81/PELI1/CD3E/CD27/IFNG/LCK/ASS1/IGF1/EFNB1/RAC2/IL6/XCL1/TNFSF4/HMGB1/GLMN/CCR7/PRKCQ/NOD2/PRDX2/HAS2/CYLD/IL6R/TNFSF14/VNN1/PAK2/NT5E/LGALS3/BCL10/GOLPH3/XBP1/CCR2/CEBPB/CD40LG/PIK3CA	87
BP	GO:0046631	alpha-beta T cell activation	46/2619	138/18670	6.658e-09	3.492e-06	2.619e-06	IRF1/RIPK2/ELF4/MALT1/IL15/RORA/PLA2G2D/SEMA4A/IL4R/PTPRC/TCF7/GPR183/ITK/HSPH1/ADA/RUNX3/TNFRSF14/CD83/HLA-E/SOCS1/HFE/BCL11B/LEF1/CD28/PTGER4/TCIRG1/RC3H2/ZAP70/PNP/CD81/CD3E/RELB/IFNG/LY9/IL6/XCL1/PRDM1/SATB1/TNFSF4/HMGB1/PRKCQ/BATF/TNFSF8/IL6R/CCR2/STOML2	46
BP	GO:0009167	purine ribonucleoside monophosphate metabolic process	87/2619	340/18670	9.306e-09	4.458e-06	3.344e-06	NUPR1/ATP1B1/TREM2/COX7A1/ENPP1/NDUFC1/SNCA/SDHC/NDUFA13/NDUFS4/NUP160/CBFA2T3/DDIT4/PID1/IMPDH2/NT5C2/BAD/NUP153/NDUFB4/ADK/PGM1/PINK1/NDUFA4/ADA/UQCR10/NDUFA8/INSR/TPR/PRKAG1/ENO2/NUP50/SLC2A6/NUDT9/CYC1/COX6C/SEC13/AK1/COX8A/RANBP2/PFKFB3/NDUFA2/TAZ/COX6A1/NDUFB6/PFKM/IFNG/NDUFB7/NUDT11/SDHD/DLD/TSPO/IGF1/CCNB1/NDUFB2/NDUFA6/GUK1/NUP210/COX5B/NDUFA10/NDUFB11/NCOR1/COQ9/NUP43/HIF1A/NDC1/OGT/NDUFB8/PRKAA1/MYH4/NDUFA3/UQCRQ/MPP1/NDUFS3/CDK1/TJP2/ALDOC/NDUFS7/NT5E/EIF6/NDUFS6/STOML2/NDUFA1/UQCRC1/AMPD3/NUP98/ADPGK/NUP62	87
BP	GO:0009126	purine nucleoside monophosphate metabolic process	87/2619	341/18670	1.08e-08	4.458e-06	3.344e-06	NUPR1/ATP1B1/TREM2/COX7A1/ENPP1/NDUFC1/SNCA/SDHC/NDUFA13/NDUFS4/NUP160/CBFA2T3/DDIT4/PID1/IMPDH2/NT5C2/BAD/NUP153/NDUFB4/ADK/PGM1/PINK1/NDUFA4/ADA/UQCR10/NDUFA8/INSR/TPR/PRKAG1/ENO2/NUP50/SLC2A6/NUDT9/CYC1/COX6C/SEC13/AK1/COX8A/RANBP2/PFKFB3/NDUFA2/TAZ/COX6A1/NDUFB6/PFKM/IFNG/NDUFB7/NUDT11/SDHD/DLD/TSPO/IGF1/CCNB1/NDUFB2/NDUFA6/GUK1/NUP210/COX5B/NDUFA10/NDUFB11/NCOR1/COQ9/NUP43/HIF1A/NDC1/OGT/NDUFB8/PRKAA1/MYH4/NDUFA3/UQCRQ/MPP1/NDUFS3/CDK1/TJP2/ALDOC/NDUFS7/NT5E/EIF6/NDUFS6/STOML2/NDUFA1/UQCRC1/AMPD3/NUP98/ADPGK/NUP62	87
BP	GO:0009141	nucleoside triphosphate metabolic process	91/2619	362/18670	1.086e-08	4.458e-06	3.344e-06	NUPR1/ATP1B1/TREM2/NME4/COX7A1/ENPP1/NDUFC1/NME7/SNCA/SDHC/NDUFA13/NDUFS4/NUP160/CBFA2T3/DDIT4/PID1/IMPDH2/NME5/BAD/NUP153/NDUFB4/ADK/PGM1/PINK1/NDUFA4/ADA/UQCR10/NDUFA8/INSR/TPR/MOCS2/PRKAG1/SAMHD1/ENO2/NUP50/DGUOK/NME3/SLC2A6/CYC1/COX6C/SEC13/AK1/COX8A/RANBP2/PFKFB3/NDUFA2/TAZ/COX6A1/NDUFB6/PFKM/IFNG/NDUFB7/SDHD/DLD/TSPO/IGF1/CCNB1/NDUFB2/NDUFA6/GUK1/NUP210/COX5B/NDUFA10/NDUFB11/NCOR1/COQ9/NUP43/HIF1A/NDC1/OGT/NDUFB8/PRKAA1/MYH4/NDUFA3/UQCRQ/CTPS1/SUCLG1/TYMS/NDUFS3/CDK1/ALDOC/NDUFS7/EIF6/NDUFS6/STOML2/NDUFA1/UQCRC1/AMPD3/NUP98/ADPGK/NUP62	91
BP	GO:0048511	rhythmic process	78/2619	295/18670	1.165e-08	4.458e-06	3.344e-06	SIK1/PTN/SETX/KDM5A/FBXW7/MYCBP2/RORA/KDM2A/EZH2/IMPDH2/GABRB1/EGFR/SERPINE1/TNFRSF11A/NTRK2/ADA/GSK3B/PRMT5/CDK4/PPARG/PLEKHA1/NAGLU/ARRB1/NTRK1/ID4/RELB/ASS1/NOS3/EGR1/HCRTR2/ADCY1/PML/MAGEL2/AXL/PTGDS/NAMPT/EREG/TOP1/AHCY/TIMP4/MAGED1/DTL/CSNK1E/TOP2A/SFPQ/NCOR1/AGRP/USP9X/OGT/HDAC1/TIMELESS/PRKAA1/HAS2/TARDBP/HLF/SUV39H2/SIX3/GDF9/NGFR/TYMS/CREB1/CDK1/ID2/ID3/TYRO3/KAT2B/EP300/CRY1/PIWIL2/SGPL1/PHLPP1/HNRNPD/ATF4/SERPINF1/HSPA5/TH/TWIST1/NR1D2	78
BP	GO:0042775	mitochondrial ATP synthesis coupled electron transport	36/2619	97/18670	1.204e-08	4.458e-06	3.344e-06	NDUFC1/SNCA/SDHC/NDUFA13/NDUFS4/NDUFB4/PINK1/NDUFA4/UQCR10/NDUFA8/CYC1/COX6C/COX8A/NDUFA2/TAZ/COX6A1/NDUFB6/NDUFB7/SDHD/DLD/CCNB1/NDUFB2/NDUFA6/COX5B/NDUFA10/NDUFB11/COQ9/NDUFB8/NDUFA3/UQCRQ/NDUFS3/CDK1/NDUFS7/NDUFS6/NDUFA1/UQCRC1	36
BP	GO:0002237	response to molecule of bacterial origin	87/2619	343/18670	1.452e-08	5.075e-06	3.806e-06	TNFAIP3/GCH1/CXCL9/NFKBIA/CSF2RB/CXCL10/NOTCH1/IRAK3/TREM2/TNFRSF1B/JAK2/CCL5/MAPK3/RIPK2/PLCG2/CXCL13/SNCA/MALT1/CXCL11/SLPI/TNIP2/LILRB2/ADAM17/LILRA2/TNIP3/IDO1/COMT/CX3CR1/SERPINE1/CARD8/TNFRSF11A/CDK4/HNRNPA0/CXCL2/CCR5/PENK/SELE/CD96/GNG12/TFPI/IRF3/PTPN22/HPGD/PTGER4/PTGFR/ELANE/F2R/NFKB1/PELI1/TRIB1/ASS1/CHUK/TSPO/NOS3/LDOC1/NR1H2/IL6/PLSCR4/GHSR/CPS1/AXL/SLC11A1/DEFA6/CASP9/MTDH/TNFSF4/HMGB1/TIMP4/CCR7/LY86/NOD2/CXCL3/MAPKAPK2/SGMS1/SRR/AKAP8/PRDX2/IL1RN/TAC1/CTSG/DEFA5/BCL10/XBP1/CXCL8/CEBPB/TH/SBNO2	87
BP	GO:0009161	ribonucleoside monophosphate metabolic process	89/2619	354/18670	1.561e-08	5.171e-06	3.879e-06	NUPR1/ATP1B1/TREM2/COX7A1/ENPP1/NDUFC1/SNCA/SDHC/NDUFA13/NDUFS4/NUP160/CBFA2T3/DDIT4/PID1/IMPDH2/NT5C2/BAD/NUP153/NDUFB4/ADK/PGM1/PINK1/NDUFA4/ADA/UQCR10/NDUFA8/INSR/TPR/PRKAG1/ENO2/NUP50/SLC2A6/NUDT9/CYC1/COX6C/SEC13/AK1/COX8A/RANBP2/PFKFB3/NDUFA2/TAZ/COX6A1/NDUFB6/PFKM/IFNG/NDUFB7/NUDT11/SDHD/DLD/TSPO/IGF1/CCNB1/NDUFB2/NDUFA6/GUK1/NUP210/COX5B/NDUFA10/NDUFB11/NCOR1/COQ9/NUP43/HIF1A/NDC1/OGT/NDUFB8/PRKAA1/MYH4/NDUFA3/UQCRQ/MPP1/NDUFS3/CDK1/TJP2/ALDOC/NDUFS7/NT5E/EIF6/NDUFS6/PRPS1/PRPS2/STOML2/NDUFA1/UQCRC1/AMPD3/NUP98/ADPGK/NUP62	89
BP	GO:0042773	ATP synthesis coupled electron transport	36/2619	98/18670	1.648e-08	5.187e-06	3.89e-06	NDUFC1/SNCA/SDHC/NDUFA13/NDUFS4/NDUFB4/PINK1/NDUFA4/UQCR10/NDUFA8/CYC1/COX6C/COX8A/NDUFA2/TAZ/COX6A1/NDUFB6/NDUFB7/SDHD/DLD/CCNB1/NDUFB2/NDUFA6/COX5B/NDUFA10/NDUFB11/COQ9/NDUFB8/NDUFA3/UQCRQ/NDUFS3/CDK1/NDUFS7/NDUFS6/NDUFA1/UQCRC1	36
BP	GO:0071902	positive regulation of protein serine/threonine kinase activity	85/2619	334/18670	1.8e-08	5.394e-06	4.046e-06	TPD52L1/DUSP5/MAP3K5/JAK2/RASGRP1/MAPK3/RIPK2/SNCA/DUSP6/TNIK/PTPRC/HGF/EZH2/ADAM17/EGFR/EGF/MAP3K11/CKS1B/TNFRSF11A/INSR/BIRC7/NTF3/KIT/BMP4/DBF4/ERBB2/MADD/MAPRE3/HTR2B/PEA15/GNG3/CD40/CXCR4/MAP4K1/CKS2/ARRB1/ELANE/F2R/MAP3K8/ADRB2/CD81/NTRK1/CCNT2/IFNG/DAXX/MAPK11/PIK3CB/IGF1/FGF18/CCNB1/TAOK1/PIK3R5/PDGFB/EPHA4/VEGFA/UBB/PLCE1/NOD2/MAGED1/LAMTOR2/MLST8/MAPKAPK2/MAP3K3/CAMK1/SOD1/PSMD10/CCNK/PRDX2/PRKAA1/TAOK3/ATP2B4/CIB1/NOD1/IKBKG/RAF1/AKAP13/CDK1/S100A12/CCND2/GHR/MNAT1/KRAS/PTK2B/CD40LG/HMGA2	85
BP	GO:0007623	circadian rhythm	60/2619	208/18670	1.912e-08	5.47e-06	4.103e-06	SIK1/SETX/KDM5A/FBXW7/MYCBP2/RORA/KDM2A/EZH2/IMPDH2/EGFR/SERPINE1/TNFRSF11A/NTRK2/ADA/GSK3B/PRMT5/CDK4/PPARG/NAGLU/NTRK1/ID4/RELB/ASS1/EGR1/HCRTR2/ADCY1/PML/MAGEL2/PTGDS/NAMPT/TOP1/AHCY/MAGED1/CSNK1E/TOP2A/SFPQ/NCOR1/AGRP/USP9X/OGT/HDAC1/TIMELESS/PRKAA1/TARDBP/SUV39H2/SIX3/NGFR/TYMS/CREB1/CDK1/ID2/ID3/EP300/CRY1/PIWIL2/PHLPP1/HNRNPD/ATF4/TH/NR1D2	60
BP	GO:0043900	regulation of multi-organism process	98/2619	405/18670	2.388e-08	6.427e-06	4.82e-06	HPGDS/TNFAIP3/AIM2/RNF125/NOTCH1/SRPK1/STAT1/BIRC3/CCL5/CHD1/MAPK3/RIPK2/ADAR/TBK1/LAMP3/FAM111A/IL15/SLPI/MICB/TNIP1/SYT11/POLR2J/POLR2I/POLR2L/LILRA2/BAD/POLR2E/POLR2F/KPNA2/PUM2/CARD8/ADA/APOE/APOBEC3C/BIRC2/TRIM26/HTRA1/TSPAN6/EXOC7/PRF1/RRP1B/LEF1/ZC3HAV1/FBXL2/PC/CD28/POLR2C/ISG20/FAM3A/CXCR4/CCL8/IFNG/NPR2/BANF1/TRIB1/TRIM21/CTDP1/IGF1/CHMP2A/EXOC2/PSMC3/GPATCH3/PML/POLR2G/MMP12/LY86/YTHDC2/TRAF3/TOP2A/OPTN/PPIE/PPM1B/IFITM2/MBL2/CCNK/PRDX2/DDX60/HDAC1/IFI16/TARDBP/CIB1/NOD1/PPIB/SEC14L1/FCN1/TIMP1/EP300/TRIM32/INHBB/RIOK3/CXCL8/CDK9/NR5A2/VAPA/HMGA2/TSPAN32/STAU1/PPIH	98
BP	GO:0007249	I-kappaB kinase/NF-kappaB signaling	72/2619	269/18670	2.451e-08	6.427e-06	4.82e-06	TNFAIP3/NFKBIA/STAT1/BIRC3/SECTM1/ECT2/RIPK2/APOL3/TBK1/ANGPT1/MALT1/RORA/PRKCB/TNIP2/TRIM22/TNIP1/TRAF5/CFLAR/S100A13/TNIP3/REL/TMEM9B/ATP2C1/ZDHHC17/PINK1/CX3CR1/CARD8/BIRC2/NDFIP1/TSPAN6/UBE2I/HTR2B/IRF3/PIM2/ROCK1/ALPK1/CD40/F2R/HSPB1/PELI1/RELB/PLK2/WLS/CHUK/IRAK4/MTDH/UBB/CCR7/NOD2/OPTN/MAP3K3/PPM1B/SNIP1/DDX1/FAIM/LIME1/HDAC1/IL1RN/DDX21/NOD1/IKBKG/AKAP13/RHOH/S100A12/BCL10/TRIM32/MYD88/RIOK3/FLNA/TLR8/VAPA/NUP62	72
BP	GO:0044839	cell cycle G2/M phase transition	71/2619	266/18670	3.454e-08	8.653e-06	6.49e-06	TPD52L1/CDC25B/CETN2/CDC7/TOPBP1/CEP135/CNTRL/SKP1/NBN/NDE1/HAUS3/CCNA2/CHEK2/PSMB9/CHEK1/ATM/SMARCD3/TPX2/BACH1/DCTN3/CDK4/HAUS2/LCMT1/SFI1/HMMR/PSMC2/USP47/DONSON/FGFR1OP/PPP1R12A/DCTN2/FOXM1/TUBA4A/PSMB6/CCNB2/PCM1/CCNB1/CCNH/PSMC3/TAOK1/CLASP1/MELK/AURKB/DYNC1H1/PSMD8/RAD51C/DTL/PSMB5/CSNK1E/OPTN/ABCB1/PSMD10/ALMS1/AKAP8/AKAP9/TAOK3/BABAM1/GTSE1/CDK1/ENSA/CDKN1A/WEE1/CEP290/MNAT1/CEP63/HSPA2/OFD1/HMGA2/RAD51B/CENPF/FBXO5	71
BP	GO:0048872	homeostasis of number of cells	67/2619	246/18670	3.575e-08	8.653e-06	6.49e-06	TNFAIP3/P4HTM/NOTCH1/STAT1/CDH2/JAK2/SOX9/ADAR/SH2B2/IL7R/SLC7A11/SOS1/GPR183/NLE1/EZH2/ADAM17/DOCK10/MERTK/ADA/IREB2/KIT/BMP4/EPB42/HOXB6/TNFRSF17/MED1/JMJD6/PTPN2/TCIRG1/RC3H2/F2R/PTBP3/CCNB2/PIK3CB/NOS3/IL6/AXL/MFHAS1/DNASE2/ZNF16/VEGFA/HMGB1/CCR7/LIPA/CXCR2/ARID4A/NFE2L1/SOD1/LAT/HIF1A/HOXA5/ERCC2/PRDX2/CYLD/PIK3CD/TNFSF14/CEBPG/ID2/SFXN1/BCL10/SH2B3/KRAS/CCR2/SMO/FH/AMPD3/TRIM58	67
BP	GO:0070661	leukocyte proliferation	77/2619	298/18670	4.19e-08	9.261e-06	6.946e-06	TNFAIP3/TREM2/CD320/IRF1/TNFRSF1B/CCL5/BTN2A2/TFRC/IGFBP2/RIPK2/TBK1/ELF4/CLU/MALT1/IL15/HLA-G/IL7R/PLA2G2D/LILRB2/PTPRC/CD38/SOS1/GPR183/ATM/IMPDH2/TNFRSF21/CTLA4/IDO1/PRNP/NCK2/ADA/TNFRSF14/HLA-E/KIT/BMP4/ERBB2/LEF1/PTPN22/CD28/CD40/TCIRG1/RC3H2/ZAP70/PNP/CD81/PELI1/MZB1/CCL8/CD3E/IGF1/EFNB1/RAC2/IL6/CD151/TYROBP/XCL1/SLC11A1/CD19/SATB1/TNFSF4/HMGB1/GLMN/PRKCQ/TNFSF8/PRDX2/BTN3A1/TAC1/CTPS1/IL6R/TNFSF14/GAL/LGALS3/CDKN1A/MS4A1/CCR2/CEBPB/CD40LG	77
BP	GO:0000086	G2/M transition of mitotic cell cycle	67/2619	247/18670	4.243e-08	9.261e-06	6.946e-06	TPD52L1/CDC25B/CETN2/CDC7/TOPBP1/CEP135/CNTRL/SKP1/NBN/NDE1/HAUS3/CCNA2/CHEK2/PSMB9/ATM/SMARCD3/TPX2/BACH1/DCTN3/CDK4/HAUS2/LCMT1/SFI1/HMMR/PSMC2/USP47/DONSON/FGFR1OP/PPP1R12A/DCTN2/FOXM1/TUBA4A/PSMB6/CCNB2/PCM1/CCNB1/CCNH/PSMC3/TAOK1/CLASP1/MELK/AURKB/DYNC1H1/PSMD8/RAD51C/DTL/PSMB5/CSNK1E/OPTN/ABCB1/PSMD10/ALMS1/AKAP9/TAOK3/CDK1/ENSA/CDKN1A/WEE1/CEP290/MNAT1/CEP63/HSPA2/OFD1/HMGA2/RAD51B/CENPF/FBXO5	67
BP	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	65/2619	237/18670	4.268e-08	9.261e-06	6.946e-06	TNFAIP3/STAT1/BIRC3/SECTM1/ECT2/RIPK2/APOL3/TBK1/ANGPT1/MALT1/RORA/PRKCB/TNIP2/TRIM22/TNIP1/TRAF5/CFLAR/S100A13/TNIP3/REL/TMEM9B/ATP2C1/ZDHHC17/PINK1/CX3CR1/CARD8/BIRC2/NDFIP1/TSPAN6/UBE2I/HTR2B/IRF3/PIM2/ALPK1/CD40/F2R/HSPB1/PELI1/PLK2/WLS/CHUK/IRAK4/MTDH/CCR7/NOD2/OPTN/MAP3K3/PPM1B/DDX1/LIME1/HDAC1/IL1RN/DDX21/NOD1/IKBKG/AKAP13/RHOH/S100A12/BCL10/TRIM32/MYD88/RIOK3/FLNA/VAPA/NUP62	65
BP	GO:0009205	purine ribonucleoside triphosphate metabolic process	84/2619	335/18670	4.463e-08	9.361e-06	7.021e-06	NUPR1/ATP1B1/TREM2/NME4/COX7A1/ENPP1/NDUFC1/NME7/SNCA/SDHC/NDUFA13/NDUFS4/NUP160/CBFA2T3/DDIT4/PID1/IMPDH2/NME5/BAD/NUP153/NDUFB4/PGM1/PINK1/NDUFA4/UQCR10/NDUFA8/INSR/TPR/MOCS2/PRKAG1/ENO2/NUP50/NME3/SLC2A6/CYC1/COX6C/SEC13/AK1/COX8A/RANBP2/PFKFB3/NDUFA2/TAZ/COX6A1/NDUFB6/PFKM/IFNG/NDUFB7/SDHD/DLD/TSPO/IGF1/CCNB1/NDUFB2/NDUFA6/GUK1/NUP210/COX5B/NDUFA10/NDUFB11/NCOR1/COQ9/NUP43/HIF1A/NDC1/OGT/NDUFB8/PRKAA1/MYH4/NDUFA3/UQCRQ/NDUFS3/CDK1/ALDOC/NDUFS7/EIF6/NDUFS6/STOML2/NDUFA1/UQCRC1/AMPD3/NUP98/ADPGK/NUP62	84
BP	GO:0009199	ribonucleoside triphosphate metabolic process	85/2619	341/18670	4.944e-08	1.004e-05	7.528e-06	NUPR1/ATP1B1/TREM2/NME4/COX7A1/ENPP1/NDUFC1/NME7/SNCA/SDHC/NDUFA13/NDUFS4/NUP160/CBFA2T3/DDIT4/PID1/IMPDH2/NME5/BAD/NUP153/NDUFB4/PGM1/PINK1/NDUFA4/UQCR10/NDUFA8/INSR/TPR/MOCS2/PRKAG1/ENO2/NUP50/NME3/SLC2A6/CYC1/COX6C/SEC13/AK1/COX8A/RANBP2/PFKFB3/NDUFA2/TAZ/COX6A1/NDUFB6/PFKM/IFNG/NDUFB7/SDHD/DLD/TSPO/IGF1/CCNB1/NDUFB2/NDUFA6/GUK1/NUP210/COX5B/NDUFA10/NDUFB11/NCOR1/COQ9/NUP43/HIF1A/NDC1/OGT/NDUFB8/PRKAA1/MYH4/NDUFA3/UQCRQ/CTPS1/NDUFS3/CDK1/ALDOC/NDUFS7/EIF6/NDUFS6/STOML2/NDUFA1/UQCRC1/AMPD3/NUP98/ADPGK/NUP62	85
BP	GO:0046034	ATP metabolic process	78/2619	305/18670	5.506e-08	1.083e-05	8.122e-06	NUPR1/ATP1B1/TREM2/COX7A1/ENPP1/NDUFC1/SNCA/SDHC/NDUFA13/NDUFS4/NUP160/CBFA2T3/DDIT4/PID1/BAD/NUP153/NDUFB4/PGM1/PINK1/NDUFA4/UQCR10/NDUFA8/INSR/TPR/PRKAG1/ENO2/NUP50/SLC2A6/CYC1/COX6C/SEC13/AK1/COX8A/RANBP2/PFKFB3/NDUFA2/TAZ/COX6A1/NDUFB6/PFKM/IFNG/NDUFB7/SDHD/DLD/TSPO/IGF1/CCNB1/NDUFB2/NDUFA6/GUK1/NUP210/COX5B/NDUFA10/NDUFB11/NCOR1/COQ9/NUP43/HIF1A/NDC1/OGT/NDUFB8/PRKAA1/MYH4/NDUFA3/UQCRQ/NDUFS3/CDK1/ALDOC/NDUFS7/EIF6/NDUFS6/STOML2/NDUFA1/UQCRC1/AMPD3/NUP98/ADPGK/NUP62	78
BP	GO:0032147	activation of protein kinase activity	83/2619	333/18670	7.105e-08	1.318e-05	9.882e-06	DUSP5/TOM1L1/GPRC5C/MAP3K5/JAK2/CCL5/ECT2/MAPK3/RIPK2/PRKAR2A/ANGPT1/MALT1/DUSP6/TNIK/STK10/PTPRC/HGF/FGF13/EGFR/EGF/MAP3K11/TPX2/PRNP/PINK1/INSR/BIRC7/NTF3/SOCS1/KIT/COPS8/BMP4/MADD/EFNA5/OSBPL8/WNT11/PEA15/GNG3/CXCR4/MAP4K1/ARRB1/F2R/MAP3K8/ADRB2/CD81/NTRK1/DAXX/CHRNA3/CARD14/AGT/MAPK11/PIK3CB/IGF1/TAOK1/MAP4K4/ANG/ADCY1/PDGFB/SLC11A1/VEGFA/UBB/PLCE1/NOD2/ATG13/LAMTOR2/MLST8/MAPKAPK2/MAP3K3/SOD1/EMP2/PRDX2/PRKAA1/TAOK3/NOD1/ADCY2/IKBKG/RAF1/IL6R/CDK1/PAK2/GHR/PTK2B/CD40LG/PIK3CA	83
BP	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	60/2619	215/18670	7.119e-08	1.318e-05	9.882e-06	MICAL1/FAM162A/MAP3K5/BIRC3/DAP/JAK2/FIS1/SNCA/LAMP3/MALT1/SMAD3/FAS/HERPUD1/NDUFA13/CFLAR/CRADD/HGF/NLE1/BAD/NLRP1/CARD8/BIRC2/BIRC7/CASP4/TNFAIP8/NOL3/LEF1/USP47/PPARG/GPX1/GPER1/CRYAB/ARRB1/CD44/F2R/CD27/LCK/APAF1/MYC/PML/CASP9/VEGFA/CASP8AP2/HMGB1/MTCH1/DHCR24/EGLN3/BIRC5/ARL6IP5/NAIP/GRAMD4/NOD1/NGFR/RAF1/TNFSF14/HIP1R/PAK2/BCL10/RPS6KA1/RNF34	60
BP	GO:0019058	viral life cycle	82/2619	328/18670	7.395e-08	1.33e-05	9.972e-06	NOTCH1/SRPK1/UBP1/CCL5/TFRC/ADAR/LAMP3/SLAMF1/FAM111A/HTATSF1/VPS37C/SLPI/TNIP1/NUP160/NUP153/EGFR/SIVA1/ITGA5/KPNA2/UVRAG/APOE/APOBEC3C/TNFRSF14/TRIM26/TPR/IDE/CCR5/NUP50/ZC3HAV1/FBXL2/PC/CD28/ITGB7/SEC13/ISG20/RANBP2/DEK/CXCR4/CHMP6/CD81/CCL8/CR1/BANF1/TRIM21/CHMP2A/PML/AXL/NUP210/UBB/YTHDC2/TOP2A/KPNB1/PPIE/IFITM2/NUP43/NDC1/CCNK/IFI16/PPIB/CHMP1B/ITGB5/CDK1/KPNA1/FCN1/TYRO3/SLC20A2/CXADR/TRIM32/KPNA3/CXCL8/PIK3C2G/ANPEP/NPC1/NR5A2/VAPA/NUP98/HMGA2/NUP62/NEDD4L/STAU1/PPIH/CXCR6	82
BP	GO:0022900	electron transport chain	54/2619	186/18670	7.617e-08	1.332e-05	9.987e-06	AKR1B1/COX7A1/NDUFC1/HAAO/QDPR/SNCA/ETFB/SDHC/NDUFA13/AKR7A3/DHRS3/NDUFS4/NDUFA4L2/GLRX5/ME2/NDUFB4/IDO1/PINK1/NQO1/NDUFA4/UQCR10/NDUFA8/FDX1/ASPH/CYC1/COX6C/COX8A/NDUFA2/TAZ/AKR7A2/COX6A1/NDUFB6/NDUFB7/SDHD/DLD/CCNB1/NDUFB2/NDUFA6/COX5B/NDUFA10/NDUFB11/COQ9/NDUFB8/NDUFA3/UQCRQ/NDUFS3/CDK1/NDUFS7/NDUFS6/TXNRD2/AKR1C4/NDUFA1/UQCRC1/NCF1	54
BP	GO:0046651	lymphocyte proliferation	71/2619	272/18670	9.054e-08	1.54e-05	1.155e-05	CD320/IRF1/TNFRSF1B/CCL5/BTN2A2/TFRC/IGFBP2/RIPK2/TBK1/ELF4/MALT1/IL15/HLA-G/IL7R/PLA2G2D/LILRB2/PTPRC/CD38/SOS1/GPR183/ATM/IMPDH2/TNFRSF21/CTLA4/IDO1/PRNP/NCK2/ADA/TNFRSF14/HLA-E/BMP4/ERBB2/LEF1/PTPN22/CD28/CD40/RC3H2/ZAP70/PNP/CD81/PELI1/MZB1/CD3E/IGF1/EFNB1/RAC2/IL6/CD151/TYROBP/XCL1/SLC11A1/CD19/SATB1/TNFSF4/HMGB1/GLMN/PRKCQ/TNFSF8/PRDX2/BTN3A1/TAC1/CTPS1/IL6R/TNFSF14/GAL/LGALS3/CDKN1A/MS4A1/CCR2/CEBPB/CD40LG	71
BP	GO:0050863	regulation of T cell activation	79/2619	314/18670	9.57e-08	1.585e-05	1.189e-05	IRF1/TNFRSF1B/SOCS6/CCL5/BTN2A2/RASGRP1/TFRC/IGFBP2/RIPK2/MALT1/IL15/HLA-G/IL7R/PLA2G2D/IL4R/LILRB2/PTPRC/SOS1/BAD/HSPH1/TNFRSF21/CTLA4/IDO1/PRNP/NCK2/ADA/RUNX3/TNFRSF14/CD83/HLA-E/SOCS1/HFE/LAX1/BMP4/ERBB2/PTPN22/CD28/IL1RL2/PTPN2/RC3H2/ZAP70/MAP3K8/PNP/CD81/PELI1/CD3E/CR1/CD27/IFNG/LCK/IGF1/EFNB1/RAC2/IL6/XCL1/PRDM1/TNFSF4/HMGB1/GLMN/CCR7/PRKCQ/NOD2/SOD1/LAT/TNFSF8/PRDX2/CYLD/CD2/IL6R/TNFSF14/VNN1/PAK2/LGALS3/BCL10/XBP1/CCR2/CEBPB/CD40LG/PIK3CA	79
BP	GO:2001233	regulation of apoptotic signaling pathway	96/2619	406/18670	1.081e-07	1.744e-05	1.308e-05	TPD52L1/TNFAIP3/SFRP1/NUPR1/FAM162A/EYA2/AR/JAK2/FIS1/FBXW7/CLU/TRAF1/SMAD3/FAS/HERPUD1/NDUFA13/CFLAR/CRADD/PTPRC/BCL2A1/HGF/NLE1/NME5/BAD/DEPTOR/NCK2/PINK1/CX3CR1/SERPINE1/GSK3B/ATF3/CREB3/MAPK7/ING2/BMP4/MADD/NOL3/GZMB/ARHGEF2/PEA15/DNAJA1/HNRNPK/TMEM14A/USP47/GPX1/PPP1R13B/GPER1/PTPN2/CD44/PRKRA/HSPB1/YWHAH/PHIP/LCK/APAF1/AGT/IGF1/NOS3/TP53BP2/TAF9B/PML/ITM2C/TRAP1/UBB/MAGED1/SCG2/SFPQ/MCL1/SOD1/SGMS1/CIDEB/PSMD10/FAIM/HIF1A/PRDX2/HDAC1/CYLD/BCL2L2/CTTN/RAF1/ACAA2/NDUFS3/RAD9A/TCF7L2/VNN1/HIP1R/PAK2/LGALS3/BCL10/TRIM32/XBP1/INHBB/STYXL1/BDNF/DDIT3/RNF34	96
BP	GO:0000280	nuclear division	96/2619	407/18670	1.223e-07	1.896e-05	1.422e-05	CDC25B/TOM1L1/SPHK1/TUBG2/NDE1/NIPBL/ASPM/KLHDC3/MYBL1/BTC/UBR2/CHEK2/CHEK1/ATM/DLGAP5/KIF2A/EGF/TPX2/PTTG1/RACGAP1/ACTR3/MKI67/PRMT5/INSR/TPR/ING2/BMP4/BUB1B/NUSAP1/SPAG5/LCMT1/CD28/SMC5/CDC14A/RMI1/NCAPH/CDCA8/CKS2/CHMP6/KNTC1/KIF18B/DRG1/PRC1/NDC80/PHIP/CENPE/KIF11/LRP5/CTDP1/IGF1/CHMP2A/NAA50/CCNB1/NCAPG/MIS12/KIF4A/CDKN1C/BRCA2/CLASP1/CDC20/EREG/ATRX/PDGFB/AURKB/PIN1/UBB/RAD51C/RAD50/BIRC5/TOP2A/RAD1/KPNB1/NFE2L1/SMC4/SPAST/KATNB1/AKAP8/SMC1A/NDC1/C11orf80/CHMP1B/TACC3/CENPC/HSPA2/SPICE1/PIWIL2/FLNA/ACTR2/RAD51B/PTTG2/CENPF/SIRT7/NUP62/POGZ/DAZL/FBXO5	96
BP	GO:0032943	mononuclear cell proliferation	71/2619	274/18670	1.235e-07	1.896e-05	1.422e-05	CD320/IRF1/TNFRSF1B/CCL5/BTN2A2/TFRC/IGFBP2/RIPK2/TBK1/ELF4/MALT1/IL15/HLA-G/IL7R/PLA2G2D/LILRB2/PTPRC/CD38/SOS1/GPR183/ATM/IMPDH2/TNFRSF21/CTLA4/IDO1/PRNP/NCK2/ADA/TNFRSF14/HLA-E/BMP4/ERBB2/LEF1/PTPN22/CD28/CD40/RC3H2/ZAP70/PNP/CD81/PELI1/MZB1/CD3E/IGF1/EFNB1/RAC2/IL6/CD151/TYROBP/XCL1/SLC11A1/CD19/SATB1/TNFSF4/HMGB1/GLMN/PRKCQ/TNFSF8/PRDX2/BTN3A1/TAC1/CTPS1/IL6R/TNFSF14/GAL/LGALS3/CDKN1A/MS4A1/CCR2/CEBPB/CD40LG	71
BP	GO:0042098	T cell proliferation	53/2619	184/18670	1.329e-07	1.991e-05	1.493e-05	IRF1/TNFRSF1B/CCL5/BTN2A2/TFRC/IGFBP2/RIPK2/ELF4/MALT1/IL15/HLA-G/PLA2G2D/LILRB2/PTPRC/SOS1/TNFRSF21/CTLA4/IDO1/PRNP/NCK2/TNFRSF14/HLA-E/BMP4/ERBB2/CD28/RC3H2/ZAP70/PNP/CD81/PELI1/CD3E/IGF1/EFNB1/RAC2/IL6/CD151/XCL1/SLC11A1/SATB1/TNFSF4/HMGB1/GLMN/PRKCQ/TNFSF8/PRDX2/BTN3A1/CTPS1/IL6R/TNFSF14/LGALS3/CCR2/CEBPB/CD40LG	53
BP	GO:0002683	negative regulation of immune system process	106/2619	463/18670	1.369e-07	2.003e-05	1.503e-05	SLAMF8/TNFAIP3/GBP1/NFKBIA/SFRP1/RNF125/NOTCH1/IRAK3/CD200/PARP3/IRF1/SOCS6/SOX9/BTN2A2/IL27RA/FBXW7/ADAR/ANGPT1/TCTA/HLA-F/HLA-G/MICB/IL7R/PLA2G2D/IL4R/LILRB2/WDR61/PTPRC/LILRA2/ATM/TNFRSF21/NMI/CTLA4/IDO1/PRNP/MERTK/GPR171/ADA/THOC1/RUNX3/TNFRSF14/N4BP2L2/HLA-E/SOCS1/HFE/HTRA1/LAX1/TSPAN6/BMP4/ERBB2/SAMHD1/CD96/PTPN22/PPARG/GPX1/PTGER4/GPER1/FAM3A/PTPN2/RC3H2/FOXF1/PELI1/CR1/TRIB1/RBM15/HMGB3/MYC/NBL1/NR1H2/GPATCH3/AXL/HLA-DOB/TYROBP/XCL1/MMP12/MFHAS1/CUEDC2/TNFSF4/HMGB1/GLMN/C4BPB/CXCR2/CST7/PPM1B/GRAMD4/HOXA5/PRDX2/IFI16/PADI2/CIB1/SEC14L1/ID2/GAL/TYRO3/LGALS3/BCL10/COL3A1/RIOK3/PTK2B/IL13RA2/HOXA7/CCR2/CEBPB/TSPAN32/LPXN/CD59	106
BP	GO:0042119	neutrophil activation	112/2619	498/18670	1.623e-07	2.321e-05	1.741e-05	SLC2A3/FUCA1/NBEAL2/IQGAP2/TNFRSF1B/DNASE1L3/CCL5/CRISPLD2/GUSB/IL15/SLPI/STK10/RAB27A/SERPINA3/LILRB2/OLR1/PTPRC/SERPINA1/LILRA2/IMPDH2/CTSA/DNASE1L1/ITGAX/ITGAL/PGM1/TIMP2/RAP2C/CFD/PRDX6/PECAM1/C6orf120/SERPINB6/RNASE2/RHOF/TMEM30A/PGRMC1/CSNK2B/ASAH1/PSMC2/ROCK1/PLD1/FGR/TOLLIP/GGH/CAT/TCIRG1/CD93/CD44/ELANE/PNP/NFKB1/CMTM6/CR1/APAF1/QPCT/CD63/FTL/PTPRN2/LRMP/PSMC3/HSPA6/VAMP7/GM2A/TYROBP/ATP8A1/SLC11A1/DYNC1H1/HMGB1/SLC2A5/CXCR2/LAMTOR2/COMMD9/KPNB1/DDOST/PPIE/NEU1/ATP11B/CD58/HBB/DNAJC3/CRISP3/GAA/PADI2/CYB5R3/GSDMD/ERP44/GCA/CTSG/ALDOC/FCN1/VNN1/S100A12/KRT1/LGALS3/CEP290/CYFIP1/MVP/PDAP1/UBR4/CXCL8/ANPEP/RAP1B/VAPA/ACTR2/AMPD3/PSAP/ALDH3B1/CFP/ARSB/DNAJC13/NRAS/CD59	112
BP	GO:0002446	neutrophil mediated immunity	112/2619	499/18670	1.809e-07	2.53e-05	1.898e-05	SLC2A3/FUCA1/NBEAL2/IQGAP2/TNFRSF1B/DNASE1L3/CRISPLD2/GUSB/SLPI/STK10/RAB27A/SERPINA3/LILRB2/OLR1/PTPRC/SERPINA1/ADAM17/IMPDH2/CTSA/DNASE1L1/ITGAX/ITGAL/PGM1/TIMP2/RAP2C/CFD/PRDX6/PECAM1/C6orf120/SERPINB6/RNASE2/RHOF/TMEM30A/PGRMC1/CSNK2B/ASAH1/PSMC2/ROCK1/PLD1/FGR/TOLLIP/GGH/CAT/TCIRG1/CD93/CD44/ELANE/PNP/NFKB1/CMTM6/TUSC2/CR1/APAF1/QPCT/CD63/FTL/PTPRN2/LRMP/PSMC3/HSPA6/VAMP7/IL6/IRAK4/GM2A/TYROBP/ATP8A1/SLC11A1/DYNC1H1/HMGB1/SLC2A5/CXCR2/LAMTOR2/COMMD9/KPNB1/DDOST/PPIE/NEU1/ATP11B/CD58/HBB/DNAJC3/CRISP3/GAA/PADI2/CYB5R3/GSDMD/ERP44/GCA/CTSG/ALDOC/FCN1/VNN1/S100A12/KRT1/LGALS3/CEP290/CYFIP1/MVP/PDAP1/UBR4/ANPEP/RAP1B/VAPA/ACTR2/AMPD3/PSAP/ALDH3B1/CFP/ARSB/DNAJC13/NRAS/CD59	112
BP	GO:0035690	cellular response to drug	88/2619	369/18670	2.436e-07	3.296e-05	2.472e-05	SLAMF8/TNFAIP3/AIM2/SFRP1/FOLR1/SPHK1/SETX/MAP3K5/SOX9/ECT2/TFRC/MAPK3/QDPR/RIPK2/SIGMAR1/KCNQ1/CCNA2/CFLAR/CHEK2/HGF/DDIT4/EZH2/BAD/EGFR/PRNP/BAIAP2/PINK1/NQO1/CDK4/FDX1/MAPK7/DDX11/EFNA5/ARHGEF2/PTPN22/HRH3/PLEKHA1/CXCR4/MAP4K1/NFKB1/NTRK1/FOLR2/PPP1R12A/ITPR2/DAXX/CHRNA3/PPM1E/CD69/ASS1/CRHBP/ANKZF1/LDOC1/KDR/MYC/IL6/EGR1/ADCY1/AXL/ATRX/PDGFB/TRAP1/PCK2/CASP9/HNRNPA1/USP8/P2RX4/NOD2/PPP3CA/SOD1/NET1/TIMELESS/PRKAA1/ATP2B4/NOD1/ADCY2/CDK1/ADIRF/CCL7/PYCR1/RAP1B/HNRNPD/ATF4/SERPINF1/HSPA5/PSAP/BCL11A/HMGA2/TH	88
BP	GO:0051249	regulation of lymphocyte activation	109/2619	485/18670	2.462e-07	3.296e-05	2.472e-05	SLAMF8/TNFAIP3/SFRP1/PARP3/CD320/IRF1/TNFRSF1B/SOCS6/CCL5/BTN2A2/RASGRP1/TFRC/IL27RA/IGFBP2/RIPK2/MALT1/IL15/HLA-F/HLA-G/TNIP2/IL7R/PLA2G2D/IL4R/LILRB2/PTPRC/CD38/SOS1/GPR183/ATM/BAD/HSPH1/TNFRSF21/CTLA4/IDO1/PRNP/MERTK/NCK2/ADA/THOC1/RUNX3/TNFRSF14/CD83/HLA-E/SOCS1/HFE/LAX1/BMP4/ERBB2/IGHM/PTPN22/CD28/IL1RL2/CD40/TOX/PTPN2/RC3H2/ZAP70/MAP3K8/PNP/CD81/PELI1/MZB1/TRBC1/CD3E/CR1/CD27/IFNG/LCK/HMGB3/IGF1/EFNB1/RAC2/IL6/AXL/TYROBP/XCL1/PRDM1/CD19/TNFSF4/HMGB1/GLMN/CCR7/PRKCQ/NOD2/IGLL5/ZFP36L2/IGLC1/SOD1/LAT/TNFSF8/PRDX2/CYLD/CD2/TAC1/IL6R/TNFSF14/ID2/GAL/VNN1/PAK2/TYRO3/LGALS3/BCL10/CDKN1A/XBP1/CCR2/CEBPB/CD40LG/PIK3CA	109
BP	GO:0045333	cellular respiration	54/2619	193/18670	2.874e-07	3.768e-05	2.826e-05	NDUFC1/SNCA/ETFB/SDHC/NDUFA13/NDUFS4/CBFA2T3/ME2/NDUFB4/PINK1/NDUFA4/UQCR10/IREB2/NDUFA8/BLOC1S1/IDE/CYC1/COX6C/COX8A/NDUFA2/TAZ/CAT/COX6A1/NDUFB6/MDH2/IFNG/NDUFB7/SDHD/SIRT3/FASTKD1/DLD/CCNB1/NDUFB2/NDUFA6/TRAP1/COX5B/NDUFA10/NDUFB11/COQ9/HIF1A/PDHB/NDUFB8/NDUFA3/UQCRQ/SUCLG1/NDUFS3/CDK1/NDUFS7/NDUFS6/MDH1/NDUFA1/FH/UQCRC1/PIK3CA	54
BP	GO:0002483	antigen processing and presentation of endogenous peptide antigen	11/2619	15/18670	3.209e-07	4.039e-05	3.029e-05	TAP1/HLA-C/HLA-F/HLA-G/HLA-A/HLA-B/HLA-E/HFE/IDE/TAPBP/TAP2	11
BP	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	11/2619	15/18670	3.209e-07	4.039e-05	3.029e-05	TAP1/HLA-C/HLA-F/HLA-G/HLA-A/HLA-B/HLA-E/HFE/IDE/TAPBP/TAP2	11
BP	GO:0018212	peptidyl-tyrosine modification	87/2619	366/18670	3.309e-07	4.041e-05	3.031e-05	EFEMP1/SFRP1/TREM2/JAK2/CCL5/CRLF1/SEMA4D/FBXW7/MAPK3/RIPK2/THBS4/ANGPT1/IL15/PTPRC/HGF/ITK/ADAM17/DYRK4/EGFR/EGF/ITGA5/PRNP/MERTK/NCK2/TPST1/NTRK2/RAP2C/NEDD9/INSR/TNFRSF14/TYK2/NTF3/SOCS1/PECAM1/KIT/DYRK2/ERBB2/EFNA5/JAK1/ARHGEF2/CTF1/FGR/CD40/PTPN2/CHMP6/FGFR1OP/TIE1/CD44/ZAP70/EPHB6/CD81/NTRK1/CBLB/CD3E/IFNG/LCK/AGT/IGF1/KDR/IL6/HBEGF/TXK/AXL/EREG/PDGFB/EPHA4/MELK/ARL2BP/VEGFA/ABI1/MATK/DOCK3/NF2/IL6R/TNK1/PAK2/GGNBP2/TYRO3/GHR/WEE1/ERBB4/SH2B3/MVP/CLK1/PTK2B/BDNF/NCF1	87
BP	GO:0051090	regulation of DNA-binding transcription factor activity	99/2619	432/18670	3.356e-07	4.041e-05	3.031e-05	ADORA3/TNFAIP3/AIM2/NFKBIA/SIK1/NUPR1/SPHK1/IRAK3/CD200/AR/DAP/JAK2/KDM5A/PRKD2/ENPP1/MAPK3/RIPK2/SRI/CLU/LRRFIP1/TRAF1/MALT1/SMAD3/PRKCB/TRIM22/TRAF5/CFLAR/MED13/EZH2/PRNP/CTNNBIP1/PINK1/CX3CR1/PIM1/CARD8/TNFRSF11A/PRKCH/TRIM26/MDFI/KIT/ARHGEF2/BEX1/PPARG/CD40/CAT/ARRB1/NFKB1/PELI1/NTRK1/TRIB1/CARD14/AGT/GTF2A2/MAPK11/TRIM21/CHUK/PRKCI/TRIM52/IL6/ADCY1/IRAK4/XCL1/BUD31/MTDH/VEGFA/TNFSF4/UBB/PRKCQ/NOD2/TRAF3/PPP3CA/PEX14/PSMD10/PRDX2/CYLD/CIB1/NOD1/IKBKG/TCF3/CEBPG/ID2/ID3/TCF7L2/S100A12/BCL10/FZD6/ATF2/EP300/TRIM32/MYD88/CRTC3/FLNA/KRAS/CD40LG/SMO/PPRC1/DDIT3/TWIST1/FZD2	99
BP	GO:0002283	neutrophil activation involved in immune response	109/2619	488/18670	3.403e-07	4.041e-05	3.031e-05	SLC2A3/FUCA1/NBEAL2/IQGAP2/TNFRSF1B/DNASE1L3/CRISPLD2/GUSB/SLPI/STK10/RAB27A/SERPINA3/LILRB2/OLR1/PTPRC/SERPINA1/LILRA2/IMPDH2/CTSA/DNASE1L1/ITGAX/ITGAL/PGM1/TIMP2/RAP2C/CFD/PRDX6/PECAM1/C6orf120/SERPINB6/RNASE2/RHOF/TMEM30A/PGRMC1/CSNK2B/ASAH1/PSMC2/ROCK1/PLD1/FGR/TOLLIP/GGH/CAT/TCIRG1/CD93/CD44/ELANE/PNP/NFKB1/CMTM6/CR1/APAF1/QPCT/CD63/FTL/PTPRN2/LRMP/PSMC3/HSPA6/VAMP7/GM2A/TYROBP/ATP8A1/SLC11A1/DYNC1H1/HMGB1/SLC2A5/CXCR2/LAMTOR2/COMMD9/KPNB1/DDOST/PPIE/NEU1/ATP11B/CD58/HBB/DNAJC3/CRISP3/GAA/PADI2/CYB5R3/GSDMD/ERP44/GCA/CTSG/ALDOC/FCN1/VNN1/S100A12/KRT1/LGALS3/CEP290/CYFIP1/MVP/PDAP1/UBR4/ANPEP/RAP1B/VAPA/ACTR2/AMPD3/PSAP/ALDH3B1/CFP/ARSB/DNAJC13/NRAS/CD59	109
BP	GO:0048285	organelle fission	102/2619	449/18670	3.48e-07	4.056e-05	3.042e-05	CDC25B/TOM1L1/SPHK1/FIS1/TUBG2/NDE1/NIPBL/ASPM/KLHDC3/MYBL1/BTC/UBR2/CHEK2/PEX19/CHEK1/ATM/DLGAP5/KIF2A/EGF/TPX2/PTTG1/RACGAP1/PINK1/ACTR3/MKI67/PRMT5/INSR/TPR/ING2/BMP4/BUB1B/NUSAP1/SPAG5/LCMT1/CD28/SMC5/CDC14A/RMI1/NCAPH/CDCA8/PEX11A/CKS2/CHMP6/KNTC1/KIF18B/DRG1/PRC1/NDC80/PHIP/CENPE/KIF11/LRP5/CTDP1/IGF1/CHMP2A/NAA50/CCNB1/NCAPG/KDR/MIS12/KIF4A/CDKN1C/BRCA2/CLASP1/CDC20/EREG/ATRX/PDGFB/AURKB/PIN1/UBB/RAD51C/RAD50/BIRC5/TOP2A/RAD1/KPNB1/NFE2L1/SMC4/SPAST/KATNB1/AKAP8/SMC1A/NDC1/C11orf80/CHMP1B/TACC3/ACOT8/CENPC/HSPA2/SPICE1/PIWIL2/FLNA/ACTR2/RAD51B/PTTG2/CENPF/SIRT7/NUP62/POGZ/DAZL/FBXO5	102
BP	GO:0002695	negative regulation of leukocyte activation	50/2619	175/18670	3.906e-07	4.469e-05	3.352e-05	TNFAIP3/SFRP1/CD200/PARP3/IRF1/SOCS6/BTN2A2/HLA-F/HLA-G/PLA2G2D/IL4R/LILRB2/PTPRC/ATM/TNFRSF21/CTLA4/IDO1/PRNP/MERTK/THOC1/RUNX3/TNFRSF14/SOCS1/HFE/LAX1/BMP4/ERBB2/PTPN22/GPER1/PTPN2/RC3H2/FOXF1/PELI1/HMGB3/AXL/TYROBP/XCL1/TNFSF4/HMGB1/GLMN/CST7/PRDX2/ID2/GAL/TYRO3/LGALS3/IL13RA2/CCR2/CEBPB/TSPAN32	50
BP	GO:0006120	mitochondrial electron transport, NADH to ubiquinone	23/2619	55/18670	4.304e-07	4.641e-05	3.481e-05	NDUFC1/SNCA/NDUFA13/NDUFS4/NDUFB4/PINK1/NDUFA4/NDUFA8/NDUFA2/NDUFB6/NDUFB7/DLD/NDUFB2/NDUFA6/NDUFA10/NDUFB11/COQ9/NDUFB8/NDUFA3/NDUFS3/NDUFS7/NDUFS6/NDUFA1	23
BP	GO:2000117	negative regulation of cysteine-type endopeptidase activity	32/2619	92/18670	4.312e-07	4.641e-05	3.481e-05	MICAL1/BIRC3/SNCA/LAMP3/HERPUD1/CFLAR/HGF/NLE1/CARD8/BIRC2/BIRC7/TNFAIP8/NOL3/LEF1/USP47/GPX1/CRYAB/ARRB1/CD44/CD27/VEGFA/DHCR24/BIRC5/CST7/NAIP/IFI16/NGFR/RAF1/TNFSF14/PAK2/RPS6KA1/RNF34	32
BP	GO:0006979	response to oxidative stress	102/2619	451/18670	4.348e-07	4.641e-05	3.481e-05	TNFAIP3/GCH1/PTGS1/PDK2/SPHK1/SCARA3/SETX/STAT1/MAP3K5/JAK2/ECT2/FBXW7/MAPK3/ERCC1/FBLN5/SNCA/SIGMAR1/CCNA2/MICB/ACOX2/SLC7A11/CFLAR/CD38/HGF/SDC1/EZH2/NME5/BAD/BRF2/EGFR/NDUFB4/PRNP/MCTP1/PDLIM1/PINK1/NQO1/ADA/APOE/GPX3/PRDX6/MAPK7/PENK/NOL3/PXDN/PLEKHA1/GPX1/CRYAB/CAT/PRKRA/GPX4/HSPB1/MSRA/PRR5L/CHUK/ANKZF1/NOS3/IPCEF1/IL6/VRK2/AKR1C3/PML/NDUFA6/PDK1/AXL/TRAP1/MELK/TXN2/MSRB2/PLA2R1/FUT8/CCR7/DHCR24/PSMB5/ARL6IP5/SFPQ/MCL1/NFE2L1/PTPRK/SOD1/HBB/NET1/WRN/HIF1A/MBL2/ERCC2/PRDX2/PRKAA1/CDK1/VNN1/MPV17/KRT1/PYCR1/SESN1/TXNRD2/PTK2B/HNRNPD/ATF4/PSAP/ALDH3B1/STC2/STAU1/NCF1	102
BP	GO:0072001	renal system development	73/2619	293/18670	4.351e-07	4.641e-05	3.481e-05	SIX1/AKR1B1/HOXA11/SFRP1/NOTCH1/STAT1/SOX9/CRLF1/PGF/ARL3/ANGPT1/NIPBL/SMAD3/CFLAR/FOXC1/NUP160/SDC1/NLE1/RBP4/CTNNBIP1/ANGPT2/PRKX/PECAM1/BMP4/WNT11/MAGI2/CEP55/HPGD/KLHL3/GCNT3/LAMA5/JMJD6/CAT/OSR2/FOXF1/APAF1/ACAT1/AGT/ASS1/MPST/SIX2/MYC/CDKN1C/EGR1/PDGFB/EPHA4/CASP9/VEGFA/CA2/IFT140/PLCE1/MAGED1/LGR5/CXCR2/TMED10/AQP2/HAS2/IL6R/ID2/ID3/MPV17/COL4A1/CEP290/HOXC11/SGPL1/SMO/EMX2/GPR4/SERPINF1/KANK2/APH1A/CENPF/PODXL	73
BP	GO:0018108	peptidyl-tyrosine phosphorylation	86/2619	363/18670	4.488e-07	4.708e-05	3.531e-05	EFEMP1/SFRP1/TREM2/JAK2/CCL5/CRLF1/SEMA4D/FBXW7/MAPK3/RIPK2/THBS4/ANGPT1/IL15/PTPRC/HGF/ITK/ADAM17/DYRK4/EGFR/EGF/ITGA5/PRNP/MERTK/NCK2/NTRK2/RAP2C/NEDD9/INSR/TNFRSF14/TYK2/NTF3/SOCS1/PECAM1/KIT/DYRK2/ERBB2/EFNA5/JAK1/ARHGEF2/CTF1/FGR/CD40/PTPN2/CHMP6/FGFR1OP/TIE1/CD44/ZAP70/EPHB6/CD81/NTRK1/CBLB/CD3E/IFNG/LCK/AGT/IGF1/KDR/IL6/HBEGF/TXK/AXL/EREG/PDGFB/EPHA4/MELK/ARL2BP/VEGFA/ABI1/MATK/DOCK3/NF2/IL6R/TNK1/PAK2/GGNBP2/TYRO3/GHR/WEE1/ERBB4/SH2B3/MVP/CLK1/PTK2B/BDNF/NCF1	86
BP	GO:0050769	positive regulation of neurogenesis	106/2619	474/18670	4.632e-07	4.779e-05	3.584e-05	BRINP1/PTN/NOTCH1/SCN1B/SETX/TREM2/NDNF/TNFRSF1B/ECT2/STMN2/SEMA4D/BRINP3/NIPBL/MACF1/ASPM/CFLAR/HGF/MMD/SS18L1/SEMA3A/EZH2/TUBB2B/ITSN2/NAP1L2/SMARCD3/BAIAP2/CX3CR1/TIMP2/ZNF365/PRKCH/NTRK2/APOE/PRMT5/KIT/BIN1/BMP4/GDF5/FGF20/EFNA5/TMEM30A/MAGI2/ARHGEF2/TRAK1/GDPD5/PPARG/FZD3/PARP6/GPER1/CXCR4/SYT17/NTRK1/IFNG/AGT/PRKCI/TSPO/NBL1/VAMP7/IL6/RND2/EPHA4/VEGFA/PLXND1/TGIF2/P2RX4/ARHGAP35/TENM3/CSNK1E/CAMK1/DCT/KATNB1/FAIM/HIF1A/HDAC1/ZC4H2/BRINP2/GOLGA4/SPEN/NGFR/TCF3/TRPV2/OLIG2/ID2/CDKL5/PLXNA1/SYT1/CYFIP1/EP300/TRIM32/CAPRIN2/FLNA/PTK2B/STYXL1/DSCAM/CCR2/FBXO38/C21orf91/SMO/SERPINF1/CAMK2B/ACTR2/HSPA5/CPNE6/BDNF/TENM4/ARSB/NEDD4L	106
BP	GO:0043406	positive regulation of MAP kinase activity	66/2619	258/18670	5.593e-07	5.573e-05	4.18e-05	TPD52L1/DUSP5/MAP3K5/JAK2/RASGRP1/MAPK3/RIPK2/DUSP6/TNIK/PTPRC/HGF/EZH2/EGFR/EGF/MAP3K11/TNFRSF11A/INSR/BIRC7/NTF3/KIT/BMP4/ERBB2/MADD/HTR2B/PEA15/GNG3/CD40/CXCR4/MAP4K1/ARRB1/ELANE/F2R/MAP3K8/CD81/NTRK1/DAXX/MAPK11/PIK3CB/IGF1/FGF18/TAOK1/PIK3R5/PDGFB/EPHA4/VEGFA/UBB/PLCE1/NOD2/MAGED1/LAMTOR2/MAPKAPK2/MAP3K3/SOD1/PRDX2/PRKAA1/TAOK3/NOD1/IKBKG/RAF1/AKAP13/CDK1/S100A12/GHR/KRAS/PTK2B/CD40LG	66
BP	GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism	59/2619	222/18670	5.64e-07	5.573e-05	4.18e-05	NOTCH1/SRPK1/STAT1/CCL5/CHD1/ADAR/LAMP3/FAM111A/SLPI/TNIP1/POLR2J/POLR2I/POLR2L/BAD/POLR2E/POLR2F/KPNA2/APOE/APOBEC3C/TRIM26/EXOC7/RRP1B/LEF1/ZC3HAV1/FBXL2/PC/CD28/POLR2C/ISG20/CXCR4/CCL8/BANF1/TRIM21/CTDP1/CHMP2A/EXOC2/PSMC3/PML/POLR2G/YTHDC2/TOP2A/PPIE/IFITM2/MBL2/CCNK/HDAC1/IFI16/TARDBP/PPIB/FCN1/EP300/TRIM32/CXCL8/CDK9/NR5A2/VAPA/HMGA2/STAU1/PPIH	59
BP	GO:0050920	regulation of chemotaxis	58/2619	217/18670	5.718e-07	5.573e-05	4.18e-05	SLAMF8/DYSF/CXCL10/PTN/NOTCH1/TREM2/LGMN/CCL5/PRKD2/SEMA4D/MAPK3/CXCL13/PGF/MYCBP2/THBS4/SMAD3/SEMA4A/GPR183/SEMA3A/ADAM17/TUBB2B/SERPINE1/ANGPT2/NTF3/CREB3/SEMA4C/PLA2G7/CXCR4/PTPN2/S1PR1/ELANE/HSPB1/SEMA3F/FGF18/KDR/RAC2/NBL1/IL6/PDGFB/XCL1/VEGFA/P2RX4/HMGB1/CCR7/CXCR2/SCG2/SEMA3E/PADI2/IL6R/TNFSF14/MPP1/CCL7/CXCL8/PTK2B/DSCAM/CCR2/USP14/VEGFB	58
BP	GO:0014065	phosphatidylinositol 3-kinase signaling	44/2619	148/18670	5.756e-07	5.573e-05	4.18e-05	JAK2/SOX9/CCL5/BTN2A2/RASGRP1/SEMA4D/MAPK3/ANGPT1/HGF/EGFR/NTRK2/INSR/NTF3/KIT/ERBB2/HTR2B/PIK3C2B/CEP55/FBXL2/CD28/PLEKHA1/FGR/PPP1R16B/GPER1/CAT/F2R/NTRK1/PRR5L/AGT/PIK3CB/IGF1/KDR/PIK3R5/MYOC/PDGFB/LIME1/PIK3CD/TYRO3/ERBB4/PIK3C2G/TWIST1/EPOR/PIK3CA/NCF1	44
BP	GO:0016570	histone modification	102/2619	454/18670	6.043e-07	5.762e-05	4.322e-05	MTF2/BAZ1A/JARID2/EYA2/JAK2/KDM5A/PRKD2/MAPK3/SUZ12/SKP1/SNCA/NIPBL/CCNA2/PRKCB/ATXN7/WDR61/DNMT1/KDM2A/UBR2/NCOA3/CHEK1/TRIP12/EZH2/ARID4B/ATM/NAP1L2/USP3/TADA3/PINK1/PRMT5/SART3/MSL3/SET/RLF/ING2/LEF1/SETD5/ZNHIT1/ZNF451/EID1/KDM3A/KDM7A/PHB/MSL2/SETMAR/JMJD6/ARRB1/SMYD2/AUTS2/TAF10/PCGF1/BRPF1/SIRT3/WDR5B/TRRAP/NAA50/CCNB1/SETD1B/ELP3/BRCA2/TAF9B/TAF7/ATRX/AURKB/VEGFA/SATB1/EED/DDB2/PAXBP1/SFPQ/RUVBL2/KAT6A/ARID4A/KAT5/RCOR1/AKAP8/YEATS2/OGT/HDAC1/PRKAA1/SETD2/PADI2/PRDM4/SUV39H2/RYBP/CDK1/CXXC1/KAT2B/RING1/ATF2/SAP30/EP300/PIWIL2/UBR5/BAZ2A/CDK9/USP21/MORF4L1/HMGA2/SIRT7/WDR70/TWIST1	102
BP	GO:0050792	regulation of viral process	56/2619	208/18670	6.903e-07	6.412e-05	4.809e-05	NOTCH1/SRPK1/STAT1/CCL5/CHD1/ADAR/LAMP3/FAM111A/SLPI/TNIP1/POLR2J/POLR2I/POLR2L/POLR2E/POLR2F/KPNA2/APOE/APOBEC3C/TRIM26/RRP1B/LEF1/ZC3HAV1/FBXL2/PC/CD28/POLR2C/ISG20/CXCR4/CCL8/BANF1/TRIM21/CTDP1/CHMP2A/PSMC3/PML/POLR2G/YTHDC2/TOP2A/PPIE/IFITM2/MBL2/CCNK/HDAC1/IFI16/TARDBP/PPIB/FCN1/EP300/TRIM32/CXCL8/CDK9/NR5A2/VAPA/HMGA2/STAU1/PPIH	56
BP	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	51/2619	183/18670	6.929e-07	6.412e-05	4.809e-05	BIRC3/SECTM1/ECT2/RIPK2/APOL3/TBK1/MALT1/PRKCB/TNIP2/TRIM22/TRAF5/CFLAR/S100A13/REL/TMEM9B/ATP2C1/ZDHHC17/PINK1/CX3CR1/BIRC2/NDFIP1/TSPAN6/UBE2I/HTR2B/IRF3/PIM2/ALPK1/CD40/F2R/PELI1/PLK2/WLS/CHUK/IRAK4/MTDH/CCR7/NOD2/MAP3K3/DDX1/IL1RN/DDX21/NOD1/IKBKG/AKAP13/S100A12/BCL10/TRIM32/MYD88/FLNA/VAPA/NUP62	51
BP	GO:0050921	positive regulation of chemotaxis	41/2619	135/18670	7.439e-07	6.785e-05	5.089e-05	DYSF/CXCL10/PTN/TREM2/LGMN/CCL5/PRKD2/MAPK3/CXCL13/PGF/THBS4/SMAD3/ADAM17/TUBB2B/SERPINE1/NTF3/CREB3/PLA2G7/CXCR4/S1PR1/HSPB1/FGF18/KDR/RAC2/IL6/PDGFB/XCL1/VEGFA/P2RX4/HMGB1/CCR7/CXCR2/SCG2/IL6R/TNFSF14/CCL7/CXCL8/PTK2B/DSCAM/CCR2/VEGFB	41
BP	GO:0044282	small molecule catabolic process	100/2619	445/18670	7.689e-07	6.912e-05	5.185e-05	CBS/FAH/HPD/CRYL1/AKR1B10/IVD/ALDH7A1/HAAO/SDS/QDPR/THNSL2/GUSB/RBKS/ECI2/ECHS1/ETFB/DDAH1/GOT1/BCKDHB/ALDH1A1/ACOX2/PCBD1/GNPDA1/PLA2G15/ENTPD4/DECR2/BAD/HSD17B10/MECR/DDO/SYNJ1/IDO1/PGM1/BDH2/ADA/APOE/APOBEC3C/PHYH/PCCB/DPYS/SORD/FUT1/HMGCL/ENO2/GCAT/GK/ECH1/ASRGL1/HMMR/TYMP/GSTZ1/NUDT9/PEX7/ESD/SNX17/CD44/PNP/HADH/HEXA/PFKM/PEX2/DDAH2/OXCT1/ECI1/ACAT1/HDC/MPST/DLD/LRP5/NOS3/SCP2/AKR1C3/APOBEC3B/AHCY/PCK2/SULT1A2/ALDH3A2/TXN2/FUT8/OAT/CYP4F11/ACADM/ACOX1/ATP2B4/ACAA2/ALDOC/HNMT/ACOT8/NT5E/INPP5E/MCAT/CRAT/ALDH6A1/FUT4/ABHD2/LPIN1/RPE/ALDH3B1/TWIST1/ADPGK	100
BP	GO:0043312	neutrophil degranulation	107/2619	485/18670	8.15e-07	7.224e-05	5.418e-05	SLC2A3/FUCA1/NBEAL2/IQGAP2/TNFRSF1B/CRISPLD2/GUSB/SLPI/STK10/RAB27A/SERPINA3/LILRB2/OLR1/PTPRC/SERPINA1/IMPDH2/CTSA/DNASE1L1/ITGAX/ITGAL/PGM1/TIMP2/RAP2C/CFD/PRDX6/PECAM1/C6orf120/SERPINB6/RNASE2/RHOF/TMEM30A/PGRMC1/CSNK2B/ASAH1/PSMC2/ROCK1/PLD1/FGR/TOLLIP/GGH/CAT/TCIRG1/CD93/CD44/ELANE/PNP/NFKB1/CMTM6/CR1/APAF1/QPCT/CD63/FTL/PTPRN2/LRMP/PSMC3/HSPA6/VAMP7/GM2A/TYROBP/ATP8A1/SLC11A1/DYNC1H1/HMGB1/SLC2A5/CXCR2/LAMTOR2/COMMD9/KPNB1/DDOST/PPIE/NEU1/ATP11B/CD58/HBB/DNAJC3/CRISP3/GAA/PADI2/CYB5R3/GSDMD/ERP44/GCA/CTSG/ALDOC/FCN1/VNN1/S100A12/KRT1/LGALS3/CEP290/CYFIP1/MVP/PDAP1/UBR4/ANPEP/RAP1B/VAPA/ACTR2/AMPD3/PSAP/ALDH3B1/CFP/ARSB/DNAJC13/NRAS/CD59	107
BP	GO:0050866	negative regulation of cell activation	54/2619	199/18670	8.296e-07	7.251e-05	5.439e-05	TNFAIP3/SFRP1/CD200/PARP3/IRF1/SOCS6/BTN2A2/HLA-F/HLA-G/PLA2G2D/IL4R/LILRB2/PTPRC/ATM/TNFRSF21/CTLA4/IDO1/PRNP/MERTK/APOE/THOC1/RUNX3/TNFRSF14/SOCS1/HFE/LAX1/BMP4/ERBB2/PTPN22/GPER1/PTPN2/RC3H2/FOXF1/PELI1/HMGB3/NOS3/AXL/TYROBP/PDGFB/XCL1/TNFSF4/HMGB1/GLMN/CST7/PRDX2/ID2/GAL/TYRO3/LGALS3/SH2B3/IL13RA2/CCR2/CEBPB/TSPAN32	54
BP	GO:0022904	respiratory electron transport chain	37/2619	117/18670	8.527e-07	7.351e-05	5.513e-05	NDUFC1/SNCA/ETFB/SDHC/NDUFA13/NDUFS4/NDUFB4/PINK1/NDUFA4/UQCR10/NDUFA8/CYC1/COX6C/COX8A/NDUFA2/TAZ/COX6A1/NDUFB6/NDUFB7/SDHD/DLD/CCNB1/NDUFB2/NDUFA6/COX5B/NDUFA10/NDUFB11/COQ9/NDUFB8/NDUFA3/UQCRQ/NDUFS3/CDK1/NDUFS7/NDUFS6/NDUFA1/UQCRC1	37
BP	GO:0052547	regulation of peptidase activity	101/2619	452/18670	8.93e-07	7.594e-05	5.696e-05	AIM2/MICAL1/FAM162A/LGMN/MAP3K5/BIRC3/DAP/JAK2/FIS1/MAPK3/RIPK2/PROS1/SNCA/LAMP3/MALT1/SMAD3/FAS/HERPUD1/SLPI/SERPINA3/NDUFA13/CFLAR/SPOCK1/CRADD/SERPINA1/PCOLCE/PSMB9/HGF/SERPINA5/NLE1/BAD/NLRP1/PTTG1/PINK1/TIMP2/SERPINE1/CARD8/APLP2/BIRC2/BIRC7/CASP4/ITIH4/BIN1/SERPINB6/TNFAIP8/NOL3/RCN3/LEF1/TFPI/USP47/ASPH/CYFIP2/PPARG/GPX1/GPER1/CRYAB/ARRB1/CD44/F2R/CR1/CD27/LCK/APAF1/AGT/PCOLCE2/MYC/PML/EPHA4/CASP9/VEGFA/SERPINA4/CASP8AP2/HMGB1/MTCH1/TIMP4/DHCR24/EGLN3/BIRC5/CST7/ARL6IP5/NAIP/COL6A3/GRAMD4/CIDEB/SPOCK2/HDAC1/IFI16/NOD1/NGFR/RAF1/TNFSF14/HIP1R/PAK2/BCL10/TIMP1/FBLN1/CST4/RPS6KA1/SERPINF1/USP14/RNF34	101
BP	GO:1903037	regulation of leukocyte cell-cell adhesion	74/2619	304/18670	9.475e-07	7.95e-05	5.963e-05	IRF1/SOCS6/CCL5/BTN2A2/RASGRP1/TFRC/IGFBP2/RIPK2/MALT1/IL15/HLA-G/IL7R/PLA2G2D/IL4R/LILRB2/PTPRC/BAD/HSPH1/TNFRSF21/CTLA4/IDO1/PRNP/NCK2/ADA/RUNX3/TNFRSF14/CD83/HLA-E/SOCS1/HFE/LAX1/BMP4/ERBB2/PTPN22/CD28/IL1RL2/PTPN2/RC3H2/CD44/ZAP70/ELANE/MAP3K8/PNP/CD81/PELI1/CD3E/CD27/IFNG/LCK/ASS1/IGF1/EFNB1/IL6/XCL1/TNFSF4/HMGB1/GLMN/CCR7/PRKCQ/NOD2/PRDX2/HAS2/CYLD/IL6R/TNFSF14/VNN1/PAK2/LGALS3/BCL10/XBP1/CCR2/CEBPB/CD40LG/PIK3CA	74
BP	GO:0035264	multicellular organism growth	43/2619	146/18670	1.019e-06	8.434e-05	6.326e-05	DIO3/LGMN/AR/GAMT/ERCC1/NIPBL/SOS1/TNKS2/FTO/ATM/CDK4/GDF5/PLEKHA1/BBS4/RMI1/FKBP8/RC3H2/ADRB2/TAF10/WDTC1/IGF1/COMP/CDKN1C/GHSR/EN1/NPY1R/ATRX/DHCR7/TMED2/SOD1/WDR11/HOXA5/ERCC2/PPIB/CREB1/STAT5A/GHR/NDUFS6/EP300/SGPL1/SMO/STC2/PIK3CA	43
BP	GO:0070997	neuron death	82/2619	348/18670	1.041e-06	8.511e-05	6.384e-05	SIX1/PIGT/NUPR1/DIO3/FAM162A/LGMN/NDNF/CD200/TNFRSF1B/MAP3K5/JAK2/CCL5/CRLF1/FIS1/FBXW7/TBK1/ANGPT1/SNCA/CLU/SIGMAR1/HLA-F/TOX3/SLC7A11/DDIT4/ATM/BAD/REL/TNFRSF21/MAP3K11/NLRP1/PRNP/PINK1/CX3CR1/NQO1/NTRK2/APOE/GSK3B/NTF3/SET/GDF5/FGF20/ROCK1/PPP1R13B/ARRB1/F2R/NTRK1/IFNG/APAF1/DAXX/PRKCI/TP53BP2/UBE2M/EGR1/EN1/AXL/NAMPT/TYROBP/CASP9/PIN1/UBB/DHCR24/EGLN3/NAIP/MCL1/SOD1/AIMP2/HIF1A/NGFR/IKBKG/CREB1/TYRO3/ATF2/KRAS/PTK2B/CEBPB/ATF4/SERPINF1/TRIM2/HSPA5/BDNF/DDIT3/PIK3CA	82
BP	GO:0097237	cellular response to toxic substance	63/2619	247/18670	1.117e-06	9.011e-05	6.758e-05	TNFAIP3/GCH1/LTC4S/PTGS1/SPHK1/AKR1B10/SETX/MAP3K5/ECT2/FIS1/FBLN5/ALOX5AP/SIGMAR1/APOM/HGF/EZH2/BAD/PINK1/NQO1/APOE/GPX3/PRDX6/MAPK7/MGST3/DDX11/GSTZ1/PXDN/PLEKHA1/GPX1/ESD/CAT/GPX4/NFKB1/NTRK1/ITPR2/DAXX/ABTB2/ANKZF1/NOS3/KDR/IPCEF1/IL6/EGR1/CPS1/AXL/PDGFB/TRAP1/GSTM3/HNRNPA1/SOD1/HBB/NET1/PRDX2/TIMELESS/PRKAA1/CDK1/ADIRF/CCL7/PYCR1/SESN1/TXNRD2/PSAP/TH	63
BP	GO:0032103	positive regulation of response to external stimulus	77/2619	323/18670	1.369e-06	0.0001091	8.182e-05	NFKBIA/DYSF/CXCL10/NUPR1/PTN/CEBPA/TREM2/LGMN/JAK2/CCL5/PRKD2/MAPK3/RIPK2/CXCL13/PGF/THBS4/TBK1/SNCA/CCL18/SMAD3/IL15/TNIP1/ADAM17/TUBB2B/EGFR/IDO1/PUM2/SERPINE1/TNFRSF11A/NTF3/HLA-E/CREB3/PLA2G7/CD28/PTGER4/CXCR4/S1PR1/HSPB1/CD81/AGT/ABCC1/FGF18/KDR/RAC2/VAMP7/IL6/GHSR/PDGFB/XCL1/VEGFA/IL17RB/P2RX4/TNFSF4/HMGB1/CCR7/LY86/NOD2/CXCR2/SCG2/OPTN/LPL/IL17RC/DDX60/TAC1/NOD1/IL6R/TNFSF14/S100A12/CCL7/MYD88/CXCL8/PTK2B/DSCAM/CCR2/CEBPB/IL17RA/VEGFB	77
BP	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling	38/2619	124/18670	1.459e-06	0.0001148	8.607e-05	JAK2/SOX9/CCL5/BTN2A2/RASGRP1/SEMA4D/MAPK3/ANGPT1/HGF/EGFR/NTRK2/INSR/NTF3/KIT/CEP55/FBXL2/CD28/FGR/PPP1R16B/GPER1/CAT/F2R/NTRK1/PRR5L/AGT/PIK3CB/IGF1/KDR/PIK3R5/MYOC/PDGFB/LIME1/PIK3CD/ERBB4/TWIST1/EPOR/PIK3CA/NCF1	38
BP	GO:0016569	covalent chromatin modification	104/2619	474/18670	1.513e-06	0.0001176	8.817e-05	MTF2/BAZ1A/JARID2/EYA2/JAK2/KDM5A/PRKD2/CHD1/MAPK3/SUZ12/SKP1/SNCA/NIPBL/CCNA2/PRKCB/ATXN7/WDR61/DNMT1/KDM2A/UBR2/NCOA3/CHEK1/TRIP12/EZH2/ARID4B/ATM/ATF7IP/NAP1L2/USP3/TADA3/PINK1/PRMT5/SART3/MSL3/SET/RLF/ING2/LEF1/SETD5/ZNHIT1/ZNF451/EID1/KDM3A/KDM7A/PHB/MSL2/SETMAR/JMJD6/ARRB1/SMYD2/AUTS2/TAF10/PCGF1/BRPF1/SIRT3/WDR5B/TRRAP/NAA50/CCNB1/SETD1B/ELP3/BRCA2/TAF9B/TAF7/ATRX/AURKB/VEGFA/SATB1/EED/DDB2/PAXBP1/SFPQ/RUVBL2/KAT6A/ARID4A/KAT5/RCOR1/AKAP8/YEATS2/OGT/HDAC1/PRKAA1/SETD2/PADI2/PRDM4/SUV39H2/RYBP/CDK1/CXXC1/KAT2B/RING1/ATF2/SAP30/EP300/PIWIL2/UBR5/BAZ2A/CDK9/USP21/MORF4L1/HMGA2/SIRT7/WDR70/TWIST1	104
BP	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress	19/2619	43/18670	1.577e-06	0.0001209	9.069e-05	MAP3K5/JAK2/FBXW7/NME5/PINK1/MAPK7/NOL3/GPX1/HSPB1/PML/PDK1/TRAP1/MELK/ARL6IP5/SFPQ/MCL1/SOD1/HIF1A/VNN1	19
BP	GO:0050670	regulation of lymphocyte proliferation	55/2619	208/18670	1.595e-06	0.0001209	9.069e-05	CD320/IRF1/TNFRSF1B/CCL5/BTN2A2/TFRC/IGFBP2/RIPK2/IL15/HLA-G/PLA2G2D/LILRB2/PTPRC/CD38/SOS1/GPR183/ATM/TNFRSF21/CTLA4/IDO1/PRNP/NCK2/ADA/TNFRSF14/HLA-E/BMP4/ERBB2/PTPN22/CD28/CD40/ZAP70/PNP/CD81/PELI1/MZB1/CD3E/IGF1/EFNB1/RAC2/IL6/TYROBP/XCL1/TNFSF4/HMGB1/GLMN/PRKCQ/TNFSF8/TAC1/IL6R/GAL/LGALS3/CDKN1A/CCR2/CEBPB/CD40LG	55
BP	GO:0045088	regulation of innate immune response	100/2619	452/18670	1.622e-06	0.0001215	9.112e-05	SLAMF8/TNFAIP3/AIM2/NFKBIA/RNF125/IRAK3/TREM2/LGMN/STAT1/IRF1/BIRC3/JAK2/CCL5/RASGRP1/RIPK2/ADAR/PLCG2/COLEC12/SKP1/TBK1/TRIL/MALT1/HLA-F/HLA-G/MICB/TNIP2/TNIP1/PSMB9/RFTN1/LILRA2/TNIP3/POLR3C/NMI/PUM2/APOE/BIRC2/HLA-E/SOCS1/TSPAN6/SAMHD1/JAK1/CD96/MED1/IRF3/PTPN22/PSMC2/PPARG/ALPK1/CRTAM/FGR/FAM3A/PTPN2/NFKB1/PELI1/CR1/RELB/IFNG/PSMB6/CHUK/HMGB3/S100A1/PSMC3/NR1H2/TLR5/GPATCH3/TXK/IRAK4/EREG/MMP12/MFHAS1/PSMD8/UBB/HMGB1/NOD2/PSMB5/TRAF3/ULBP2/MAPKAPK2/SFPQ/GRAMD4/PSMD10/DDX60/CYLD/IFI16/MUC5AC/NOD1/IKBKG/RAF1/SEC14L1/FCN1/PAK2/TYRO3/BCL10/EP300/MYD88/RIOK3/KRAS/TLR8/ICAM3/NRAS	100
BP	GO:0001655	urogenital system development	78/2619	330/18670	1.667e-06	0.0001234	9.255e-05	SIX1/AKR1B1/HOXA11/SFRP1/NOTCH1/AR/STAT1/SOX9/CRLF1/PGF/ARL3/ANGPT1/NIPBL/SMAD3/CFLAR/FOXC1/NUP160/SDC1/NLE1/RBP4/CTNNBIP1/ANGPT2/PRKX/PECAM1/RXRA/BMP4/CYP7B1/WNT11/MAGI2/CEP55/HPGD/KLHL3/GCNT3/LAMA5/JMJD6/CAT/OSR2/FOXF1/ID4/APAF1/ACAT1/AGT/ASS1/MPST/SIX2/MYC/CDKN1C/EGR1/PDGFB/EPHA4/CASP9/VEGFA/CA2/IFT140/PLCE1/MAGED1/LGR5/CXCR2/TMED10/AQP2/HAS2/IL6R/ID2/ID3/MPV17/COL4A1/CEP290/HOXC11/SGPL1/SMO/EMX2/GPR4/SERPINF1/KANK2/APH1A/PSAP/CENPF/PODXL	78
BP	GO:0097191	extrinsic apoptotic signaling pathway	58/2619	224/18670	1.749e-06	0.0001273	9.545e-05	TNFAIP3/SFRP1/EYA2/AR/TNFRSF1B/JAK2/TRAF1/SMAD3/FAS/NDUFA13/CFLAR/CRADD/PTPRC/BCL2A1/HGF/BAD/DEPTOR/SIVA1/SERPINE1/GSK3B/ATF3/MAPK7/BMP4/MADD/NOL3/ARHGEF2/PEA15/GPX1/GPER1/CD27/PHIP/IFNG/DAXX/AGT/IGF1/NOS3/PML/ITM2C/SORT1/CASP9/CASP8AP2/SCG2/MCL1/MKNK2/FAIM/PRDX2/CYLD/BCL2L2/CTTN/CIB1/RAF1/IL6R/TCF7L2/PAK2/LGALS3/BCL10/GABARAP/RNF34	58
BP	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	29/2619	84/18670	1.759e-06	0.0001273	9.545e-05	MICAL1/BIRC3/SNCA/LAMP3/HERPUD1/CFLAR/HGF/NLE1/BIRC2/BIRC7/TNFAIP8/NOL3/LEF1/USP47/GPX1/CRYAB/ARRB1/CD44/CD27/VEGFA/DHCR24/BIRC5/NAIP/NGFR/RAF1/TNFSF14/PAK2/RPS6KA1/RNF34	29
BP	GO:0052548	regulation of endopeptidase activity	95/2619	425/18670	1.839e-06	0.0001295	9.715e-05	AIM2/MICAL1/FAM162A/LGMN/MAP3K5/BIRC3/DAP/JAK2/FIS1/RIPK2/PROS1/SNCA/LAMP3/MALT1/SMAD3/FAS/HERPUD1/SLPI/SERPINA3/NDUFA13/CFLAR/SPOCK1/CRADD/SERPINA1/PSMB9/HGF/SERPINA5/NLE1/BAD/NLRP1/PTTG1/TIMP2/SERPINE1/CARD8/APLP2/BIRC2/BIRC7/CASP4/ITIH4/BIN1/SERPINB6/TNFAIP8/NOL3/LEF1/TFPI/USP47/ASPH/CYFIP2/PPARG/GPX1/GPER1/CRYAB/ARRB1/CD44/F2R/CR1/CD27/LCK/APAF1/AGT/MYC/PML/EPHA4/CASP9/VEGFA/SERPINA4/CASP8AP2/HMGB1/MTCH1/TIMP4/DHCR24/EGLN3/BIRC5/CST7/ARL6IP5/NAIP/COL6A3/GRAMD4/CIDEB/SPOCK2/HDAC1/IFI16/NOD1/NGFR/RAF1/TNFSF14/HIP1R/PAK2/BCL10/TIMP1/CST4/RPS6KA1/SERPINF1/USP14/RNF34	95
BP	GO:0051091	positive regulation of DNA-binding transcription factor activity	65/2619	261/18670	1.854e-06	0.0001295	9.715e-05	AIM2/SPHK1/IRAK3/CD200/AR/JAK2/PRKD2/RIPK2/CLU/LRRFIP1/TRAF1/MALT1/SMAD3/PRKCB/TRIM22/TRAF5/CFLAR/PINK1/CX3CR1/TNFRSF11A/PRKCH/TRIM26/KIT/ARHGEF2/BEX1/PPARG/CD40/CAT/NFKB1/NTRK1/CARD14/AGT/GTF2A2/TRIM21/CHUK/PRKCI/TRIM52/IL6/ADCY1/IRAK4/BUD31/MTDH/VEGFA/UBB/PRKCQ/NOD2/PPP3CA/CIB1/NOD1/IKBKG/TCF3/CEBPG/S100A12/BCL10/ATF2/EP300/TRIM32/MYD88/CRTC3/KRAS/CD40LG/SMO/PPRC1/DDIT3/FZD2	65
BP	GO:0050663	cytokine secretion	61/2619	240/18670	1.86e-06	0.0001295	9.715e-05	TNFAIP3/GBP1/AIM2/DYSF/NOTCH1/CD200/TNFRSF1B/BTN2A2/RASGRP1/IL27RA/MAPK3/RIPK2/ANGPT1/SYT11/IL4R/S100A13/LILRA2/TNFRSF21/NLRP1/CARD8/TNFRSF14/SOCS1/HTR2B/IRF3/PTPN22/CRTAM/FGR/PTGER4/TCIRG1/F2R/PNP/POSTN/IFNG/AGT/MAPK11/CHUK/GHSR/TLR5/PML/RBPJ/MMP12/IL17RB/HMGB1/GLMN/CCR7/NOD2/FERMT1/CD58/LPL/IL17RC/BTN3A1/CD2/GSDMD/FCN1/S100A12/XBP1/LCP2/TLR8/IL17RA/TWIST1/SRGN	61
BP	GO:0032944	regulation of mononuclear cell proliferation	55/2619	209/18670	1.873e-06	0.0001295	9.715e-05	CD320/IRF1/TNFRSF1B/CCL5/BTN2A2/TFRC/IGFBP2/RIPK2/IL15/HLA-G/PLA2G2D/LILRB2/PTPRC/CD38/SOS1/GPR183/ATM/TNFRSF21/CTLA4/IDO1/PRNP/NCK2/ADA/TNFRSF14/HLA-E/BMP4/ERBB2/PTPN22/CD28/CD40/ZAP70/PNP/CD81/PELI1/MZB1/CD3E/IGF1/EFNB1/RAC2/IL6/TYROBP/XCL1/TNFSF4/HMGB1/GLMN/PRKCQ/TNFSF8/TAC1/IL6R/GAL/LGALS3/CDKN1A/CCR2/CEBPB/CD40LG	55
BP	GO:0006090	pyruvate metabolic process	44/2619	154/18670	1.9e-06	0.00013	9.747e-05	PDK2/NUPR1/SDS/MPC2/NUP160/CBFA2T3/DDIT4/ME2/NUP153/PGM1/BSG/INSR/TPR/PRKAG1/ENO2/NUP50/SLC2A6/GSTZ1/PC/SEC13/RANBP2/PFKFB3/PFKM/IFNG/DLD/IGF1/PDK1/NUP210/PCK2/NCOR1/NUP43/SRR/HIF1A/PDHB/NDC1/OGT/PRKAA1/ALDOC/GLO1/EIF6/MPC1/NUP98/ADPGK/NUP62	44
BP	GO:0046777	protein autophosphorylation	60/2619	235/18670	1.921e-06	0.00013	9.751e-05	TOM1L1/SIK1/IRAK3/JAK2/PRKD2/ENPP1/MAPK3/NBN/TNIK/STK10/STK17B/ATR/PTPRC/CHEK2/ITK/ATM/EGFR/MAP3K11/PINK1/PIM1/NTRK2/RAP2C/PRKX/GSK3B/INSR/KIT/ERBB2/PIM2/FGR/MAP4K1/ZAP70/NTRK1/LCK/KDR/TAOK1/VRK2/TXK/PDGFB/EPHA4/MELK/TRIM24/AURKB/VEGFA/RAD50/NLK/MAPKAPK2/MAP3K3/MKNK2/TAOK3/TNK1/CDKL5/PAK2/TYRO3/ERBB4/MARK3/MVP/CLK1/PTK2B/CAMK2B/PASK	60
BP	GO:0048017	inositol lipid-mediated signaling	50/2619	184/18670	1.993e-06	0.0001334	0.0001001	JAK2/SOX9/CCL5/BTN2A2/RASGRP1/SEMA4D/MAPK3/PLCG2/ANGPT1/HGF/EGFR/NTRK2/INSR/NTF3/KIT/ERBB2/HTR2B/PIK3C2B/CEP55/FBXL2/CD28/PLD1/PLEKHA1/FGR/PPP1R16B/GPER1/CAT/F2R/NTRK1/PRR5L/AGT/PIK3CB/IGF1/KDR/PIK3R5/MYOC/PDGFB/PLCE1/LIME1/OGT/MUC5AC/PIK3CD/TYRO3/ERBB4/PIK3C2G/EXOC1/TWIST1/EPOR/PIK3CA/NCF1	50
BP	GO:0043405	regulation of MAP kinase activity	79/2619	337/18670	2.014e-06	0.0001334	0.0001001	TPD52L1/DUSP5/SFRP1/IRAK3/MAP3K5/JAK2/RASGRP1/MAPK3/RIPK2/DUSP6/TNIK/UCHL1/PTPRC/HGF/EZH2/EGFR/EGF/MAP3K11/TNFRSF11A/APOE/INSR/BIRC7/NTF3/KIT/LAX1/BMP4/ERBB2/MADD/HTR2B/PEA15/GNG3/DNAJA1/PTPN22/CD40/CXCR4/MAP4K1/ARRB1/ELANE/F2R/MAP3K8/CD81/NTRK1/RGS4/DAXX/TRIB1/MAPK11/PIK3CB/IGF1/FGF18/TAOK1/PIK3R5/PDGFB/EPHA4/DUSP2/VEGFA/UBB/PLCE1/NOD2/MAGED1/LAMTOR2/MAPKAPK2/MAP3K3/SOD1/LIME1/PRDX2/PRKAA1/TAOK3/NOD1/IKBKG/RAF1/AKAP13/CDK1/S100A12/GHR/SH2B3/KRAS/PTK2B/CD40LG/NUP62	79
BP	GO:0071216	cellular response to biotic stimulus	60/2619	236/18670	2.229e-06	0.0001446	0.0001085	TNFAIP3/CXCL9/NFKBIA/CXCL10/TREM2/TNFRSF1B/CCL5/MAPK3/RIPK2/CXCL13/MALT1/CXCL11/TNIP2/LILRB2/LILRA2/TNIP3/CX3CR1/SERPINE1/CARD8/GSK3B/CDK4/CXCL2/CCR5/TFPI/IRF3/PTPN22/NFKB1/TMCO1/APAF1/TRIB1/ASS1/TSPO/NOS3/LDOC1/NR1H2/IL6/PLSCR4/GHSR/AXL/DEFA6/MTDH/TNFSF4/HMGB1/LY86/NOD2/CXCL3/SGMS1/AKAP8/SMC1A/PRDX2/IL1RN/CTSG/DEFA5/BCL10/XBP1/CXCL8/CEBPB/HSPA5/DDIT3/SBNO2	60
BP	GO:0097193	intrinsic apoptotic signaling pathway	70/2619	289/18670	2.229e-06	0.0001446	0.0001085	PDK2/NUPR1/TNFRSF1B/MAP3K5/JAK2/FIS1/FBXW7/CLU/NBN/HERPUD1/NDUFA13/BCL2A1/CHEK2/DDIT4/ATM/NME5/BAD/NCK2/PINK1/CASP4/CREB3/MAPK7/ING2/DYRK2/NOL3/ARHGEF2/DNAJA1/HNRNPK/USP47/GPX1/PPP1R13B/FHIT/PTPN2/CD44/PRKRA/HSPB1/LCK/APAF1/TP53BP2/BRCA2/TAF9B/PML/PDK1/TRAP1/MELK/CASP9/UBB/ARL6IP5/SFPQ/MCL1/SOD1/SGMS1/CIDEB/HIF1A/HDAC1/CYLD/IFI16/BCL2L2/NDUFS3/RAD9A/VNN1/CDKN1A/EP300/TRIM32/XBP1/CUL2/STYXL1/CEBPB/ATF4/DDIT3	70
BP	GO:1901796	regulation of signal transduction by p53 class mediator	49/2619	180/18670	2.377e-06	0.0001526	0.0001145	TOPBP1/NBN/ATR/CHEK2/CHEK1/ATM/BARD1/DNA2/TPX2/RPA1/PRMT5/PRKAG1/ING2/DYRK2/PRKAB1/CSNK2B/RPA3/HNRNPK/PPP1R13B/RMI1/CD44/SMYD2/TAF10/BRPF1/MAPK11/TP53BP2/TAF9B/PML/TAF7/TRIM24/AURKB/PIN1/PLA2R1/UBB/RAD50/RAD1/CHD3/KAT6A/KAT5/WRN/PSMD10/HDAC1/BANP/PRKAA1/RAD9A/EP300/RFC2/TWIST1/RNF34	49
BP	GO:0051250	negative regulation of lymphocyte activation	42/2619	146/18670	2.657e-06	0.0001689	0.0001267	TNFAIP3/SFRP1/PARP3/IRF1/SOCS6/BTN2A2/HLA-F/HLA-G/PLA2G2D/IL4R/LILRB2/ATM/TNFRSF21/CTLA4/IDO1/PRNP/MERTK/THOC1/RUNX3/TNFRSF14/SOCS1/HFE/LAX1/BMP4/ERBB2/PTPN22/PTPN2/RC3H2/PELI1/HMGB3/AXL/TYROBP/XCL1/TNFSF4/HMGB1/GLMN/PRDX2/ID2/GAL/TYRO3/LGALS3/CEBPB	42
BP	GO:0048015	phosphatidylinositol-mediated signaling	49/2619	181/18670	2.821e-06	0.0001772	0.0001329	JAK2/SOX9/CCL5/BTN2A2/RASGRP1/SEMA4D/MAPK3/PLCG2/ANGPT1/HGF/EGFR/NTRK2/INSR/NTF3/KIT/ERBB2/HTR2B/PIK3C2B/CEP55/FBXL2/CD28/PLEKHA1/FGR/PPP1R16B/GPER1/CAT/F2R/NTRK1/PRR5L/AGT/PIK3CB/IGF1/KDR/PIK3R5/MYOC/PDGFB/PLCE1/LIME1/OGT/MUC5AC/PIK3CD/TYRO3/ERBB4/PIK3C2G/EXOC1/TWIST1/EPOR/PIK3CA/NCF1	49
BP	GO:0070663	regulation of leukocyte proliferation	57/2619	222/18670	2.844e-06	0.0001772	0.0001329	TNFAIP3/CD320/IRF1/TNFRSF1B/CCL5/BTN2A2/TFRC/IGFBP2/RIPK2/IL15/HLA-G/PLA2G2D/LILRB2/PTPRC/CD38/SOS1/GPR183/ATM/TNFRSF21/CTLA4/IDO1/PRNP/NCK2/ADA/TNFRSF14/HLA-E/BMP4/ERBB2/PTPN22/CD28/CD40/ZAP70/PNP/CD81/PELI1/MZB1/CCL8/CD3E/IGF1/EFNB1/RAC2/IL6/TYROBP/XCL1/TNFSF4/HMGB1/GLMN/PRKCQ/TNFSF8/TAC1/IL6R/GAL/LGALS3/CDKN1A/CCR2/CEBPB/CD40LG	57
BP	GO:0051222	positive regulation of protein transport	93/2619	418/18670	2.896e-06	0.0001787	0.000134	ZIC1/AIM2/TREM2/JAK2/ECT2/RPH3AL/RASGRP1/FIS1/FBXW7/MAPK3/RIPK2/SEC24A/SRI/SMAD3/MICALL2/IL4R/MPC2/CD38/LILRA2/RBP4/BAD/EGFR/NLRP1/PRNP/PINK1/CARD8/GSK3B/TNFRSF14/HLA-E/TPR/ERBB2/HTR2B/TMEM30A/IRF3/PTPN22/ANK3/CRTAM/FGR/PTGER4/GPER1/ARRB1/F2R/CD81/POSTN/OXCT1/IFNG/PRR5L/SIRT3/WLS/MAPK11/PCM1/CHUK/IGF1/RAC2/SEC16A/ANG/IL6/MMP12/IL17RB/TNFSF4/HMGB1/GLMN/NOD2/ANO1/FERMT1/ATG13/EDEM1/VAMP2/CD58/CAMK1/LPL/HIF1A/IL17RC/PRKAA1/TARDBP/CD2/CIB1/GSDMD/GTSE1/FCN1/TCF7L2/CEP290/GOLPH3/XBP1/UBL5/FLNA/UBR5/TLR8/SMO/EXOC1/MYH10/IL17RA/TWIST1	93
BP	GO:0070555	response to interleukin-1	54/2619	207/18670	3.077e-06	0.000188	0.000141	GBP1/NFKBIA/GBP2/SFRP1/IRAK3/SOX9/CCL5/MAPK3/RIPK2/SKP1/SNCA/CCL18/RORA/TNIP2/CD38/PSMB9/TNFRSF11A/SELE/TFPI/PSMC2/IL1RL2/TOLLIP/MAP3K8/NFKB1/PELI1/CCL8/PSMB6/MAPK11/CHUK/PRKCI/PSMC3/IL6/EGR1/VRK2/IRAK4/XCL1/PSMD8/UBB/NOD2/YTHDC2/PSMB5/MAP3K3/CCL13/PSMD10/HIF1A/HAS2/IL1RN/NOD1/IKBKG/HNMT/CCL7/MYD88/CXCL8/CEBPB	54
BP	GO:0060333	interferon-gamma-mediated signaling pathway	30/2619	91/18670	3.493e-06	0.0002114	0.0001585	GBP1/GBP2/HLA-C/STAT1/IRF1/JAK2/HLA-DRB4/HLA-F/HLA-G/TRIM22/HLA-A/NMI/TRIM26/HLA-B/HLA-E/SOCS1/JAK1/MED1/IRF3/PPARG/PTPN2/CD44/IFNG/TRIM21/NR1H2/TXK/PML/HLA-DQB1/OAS2/CAMK2B	30
BP	GO:0050708	regulation of protein secretion	102/2619	472/18670	3.875e-06	0.0002322	0.0001742	TNFAIP3/GBP1/AIM2/SFRP1/TREM2/CD200/TNFRSF1B/JAK2/CCL5/RPH3AL/BTN2A2/RASGRP1/IL27RA/MAPK3/RIPK2/SEC24A/ANGPT1/SRI/SLC25A4/SYT11/ARFIP1/IL4R/MPC2/CD38/ARL2/LILRA2/RBP4/BAD/EGFR/TNFRSF21/NLRP1/CARD8/APOE/TNFRSF14/HLA-E/SOCS1/DNAJC1/EFNA5/HTR2B/IRF3/PTPN22/RAB11FIP1/CRTAM/FGR/CD40/PTGER4/GPER1/TCIRG1/ARRB1/F2R/HADH/POSTN/OXCT1/IFNG/ITPR2/SIRT3/WLS/MAPK11/CHUK/LRP5/IGF1/MAP4K4/ANG/IL6/GHSR/TLR5/PML/ARL2BP/MMP12/IL17RB/TNFSF4/HMGB1/GLMN/ABCC8/CCR7/NOD2/ANO1/FERMT1/PPP3CA/SSTR5/CD58/LPL/HIF1A/IL17RC/TARDBP/CD2/GSDMD/CACNA1D/RHBDF2/FCN1/TCF7L2/ENSA/GOLPH3/XBP1/INHBB/TLR8/CD40LG/EXOC1/MYH10/IL17RA/TWIST1/SRGN	102
BP	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	29/2619	87/18670	3.939e-06	0.0002339	0.0001754	JAK2/SOX9/CCL5/SEMA4D/ANGPT1/HGF/NTRK2/INSR/NTF3/KIT/CD28/FGR/GPER1/CAT/F2R/NTRK1/PRR5L/AGT/PIK3CB/IGF1/KDR/PIK3R5/MYOC/PDGFB/PIK3CD/ERBB4/EPOR/PIK3CA/NCF1	29
BP	GO:0001101	response to acid chemical	79/2619	343/18670	4.109e-06	0.0002417	0.0001813	SIX1/BRINP1/AKR1B1/SFRP1/PTN/FOLR1/SETX/WNT5B/SOX9/FIS1/IGFBP2/BRINP3/PEMT/SLC10A3/MICB/NDUFA13/DNMT1/CD38/UBR2/PID1/ATM/RBP4/BAD/EGFR/BAIAP2/PINK1/NQO1/NTRK2/CDK4/SOCS1/RRAGA/HMGCL/RXRA/WNT11/PPARG/PTGER4/PTGFR/CAT/TIE1/NTRK1/FOLR2/ASS1/CHUK/CCNB1/KDR/EGR1/AKR1C3/CPS1/PDGFB/VEGFA/TNFSF4/PKD2L1/CCR7/LAMTOR2/LPL/AKAP8/AQP2/PRKAA1/ATP2B4/BRINP2/TYMS/CREB1/ID3/RRAGD/COL4A1/ATF2/XBP1/COL3A1/SESN1/FABP3/PTK2B/AKR1C4/HNRNPD/FZD7/CEBPB/SERPINF1/BCL11A/ASNS/TH	79
BP	GO:0071229	cellular response to acid chemical	54/2619	209/18670	4.198e-06	0.0002438	0.0001828	SIX1/BRINP1/SFRP1/FOLR1/SETX/WNT5B/SOX9/BRINP3/NDUFA13/DNMT1/UBR2/PID1/ATM/EGFR/BAIAP2/PINK1/NTRK2/CDK4/SOCS1/RRAGA/WNT11/PPARG/PTGER4/PTGFR/FOLR2/ASS1/CCNB1/KDR/EGR1/AKR1C3/CPS1/PDGFB/VEGFA/TNFSF4/LAMTOR2/LPL/AKAP8/AQP2/PRKAA1/BRINP2/CREB1/ID3/RRAGD/COL4A1/XBP1/COL3A1/SESN1/PTK2B/AKR1C4/HNRNPD/FZD7/CEBPB/SERPINF1/BCL11A	54
BP	GO:0072331	signal transduction by p53 class mediator	65/2619	267/18670	4.222e-06	0.0002438	0.0001828	PDK2/NUPR1/TOPBP1/NBN/ATR/CRADD/CHEK2/DDIT4/CHEK1/ATM/BARD1/DNA2/TPX2/RPA1/PRMT5/PRKAG1/ING2/DYRK2/PRKAB1/CSNK2B/RPA3/HNRNPK/PPP1R13B/FHIT/RMI1/CD44/SMYD2/TAF10/FOXM1/PLK2/BRPF1/MAPK11/CCNB1/TP53BP2/BRCA2/TAF9B/PML/TAF7/ATRX/TRIM24/AURKB/PIN1/PLA2R1/UBB/RAD50/BATF/RAD1/CHD3/KAT6A/KAT5/WRN/PSMD10/HDAC1/BANP/PRKAA1/IFI16/GTSE1/CDK1/RAD9A/CDKN1A/EP300/RFC2/TWIST1/RBL2/RNF34	65
BP	GO:1904951	positive regulation of establishment of protein localization	99/2619	456/18670	4.344e-06	0.0002485	0.0001864	ZIC1/AIM2/TREM2/JAK2/ECT2/RPH3AL/CEP135/RASGRP1/FIS1/FBXW7/MAPK3/RIPK2/SEC24A/SRI/SMAD3/MICALL2/IL4R/MPC2/CD38/LILRA2/RBP4/BAD/EGFR/NLRP1/PRNP/PINK1/CARD8/GSK3B/CORO2B/TNFRSF14/HLA-E/TPR/ERBB2/HTR2B/TMEM30A/GZMB/IRF3/PTPN22/PPP1R13B/ANK3/CRTAM/FGR/PTGER4/GPER1/ARRB1/F2R/CD81/YWHAH/POSTN/OXCT1/IFNG/PRR5L/SIRT3/WLS/MAPK11/PCM1/CHUK/IGF1/TP53BP2/RAC2/SEC16A/ANG/IL6/MMP12/IL17RB/TNFSF4/HMGB1/GLMN/NOD2/ANO1/FERMT1/ATG13/EDEM1/VAMP2/CD58/CAMK1/LPL/HIF1A/IL17RC/PRKAA1/TARDBP/CD2/CIB1/GSDMD/GTSE1/FCN1/TCF7L2/CEP290/GOLPH3/XBP1/UBL5/FLNA/UBR5/TLR8/SMO/EXOC1/MYH10/IL17RA/TWIST1	99
BP	GO:0046394	carboxylic acid biosynthetic process	100/2619	462/18670	4.466e-06	0.0002532	0.0001899	HPGDS/CBS/GCH1/LTC4S/PTGS1/NUPR1/UST/BHMT2/TBXAS1/HAAO/SDS/LIPC/THNSL2/GAMT/CH25H/ALOX5AP/OSBPL3/GOT1/EPHX2/ACSM5/ACOX2/ERLIN2/DHRS9/NUP160/CBFA2T3/DDIT4/TECR/DECR2/NUP153/MECR/EGF/IDO1/PGM1/INSR/SLC27A5/NAALAD2/TPR/PRKAG1/MGST3/CYP7B1/GSTM4/PRKAB1/ENO2/NUP50/SLC2A6/UROS/HPGD/SEC13/RANBP2/PFKFB3/SERINC5/GPX4/NFKB1/PFKM/IFNG/APOC1/WDTC1/GATM/ASS1/IGF1/SCD5/NR1H2/SCP2/AKR1C3/PSPH/CPS1/PTGDS/PDGFB/NUP210/ALDH1A3/OAT/NCOR1/NUP43/LPL/SRR/HIF1A/NDC1/OGT/PRKAA1/HAS2/ATP2B4/FA2H/SEPHS1/ALDOC/ACOT8/MCAT/VCAN/EIF6/PYCR1/XBP1/CBR1/PLP1/ALDH18A1/AKR1C4/ABHD2/CHST12/NUP98/ASNS/ADPGK/NUP62	100
BP	GO:0045619	regulation of lymphocyte differentiation	46/2619	169/18670	4.791e-06	0.0002649	0.0001987	SLAMF8/SFRP1/IRF1/BTN2A2/RASGRP1/RIPK2/MALT1/IL15/HLA-G/IL7R/IL4R/LILRB2/PTPRC/SOS1/BAD/CTLA4/ADA/RUNX3/CD83/SOCS1/BMP4/ERBB2/CD28/IL1RL2/TOX/PTPN2/RC3H2/ZAP70/PNP/CR1/CD27/IFNG/HMGB3/AXL/PRDM1/TNFSF4/HMGB1/ZFP36L2/SOD1/PRDX2/CYLD/CD2/ID2/VNN1/XBP1/CCR2	46
BP	GO:0007088	regulation of mitotic nuclear division	45/2619	164/18670	4.8e-06	0.0002649	0.0001987	TOM1L1/SPHK1/NIPBL/BTC/CHEK1/ATM/DLGAP5/EGF/PTTG1/MKI67/PRMT5/INSR/TPR/BMP4/BUB1B/NUSAP1/LCMT1/CD28/SMC5/CDC14A/KNTC1/DRG1/NDC80/PHIP/CENPE/KIF11/LRP5/IGF1/CHMP2A/CCNB1/CDKN1C/CDC20/EREG/ATRX/PDGFB/AURKB/PIN1/NFE2L1/SMC1A/CHMP1B/TACC3/PTTG2/CENPF/NUP62/FBXO5	45
BP	GO:0035821	modification of morphology or physiology of other organism	45/2619	164/18670	4.8e-06	0.0002649	0.0001987	CCL5/CHD1/SMAD3/SLPI/TNIP1/APOL1/BAD/KPNA2/APOE/INSR/RRAGA/RXRA/PRF1/RRP1B/LEF1/FBXL2/PC/ELANE/CCL8/TUSC2/IFNG/CTDP1/GNLY/PSMC3/DEFA6/HMGN2/YTHDC2/KPNB1/CCL13/MBL2/CCNK/HDAC1/TARDBP/GSDMD/PPIB/CTSG/TYMS/DEFA5/KPNA1/S100A12/EP300/KPNA3/VAPA/HMGA2/REG3A	45
BP	GO:1900034	regulation of cellular response to heat	27/2619	79/18670	4.924e-06	0.0002673	0.0002005	IER5/MAPK3/ATR/NUP160/ATM/HSPH1/NUP153/RPA1/GSK3B/CHORDC1/TPR/NUP50/RPA3/SEC13/RANBP2/CRYAB/HSBP1/NUP210/BAG1/MLST8/MAPKAPK2/NUP43/NDC1/EP300/CAMK2B/NUP98/NUP62	27
BP	GO:0016053	organic acid biosynthetic process	100/2619	463/18670	4.926e-06	0.0002673	0.0002005	HPGDS/CBS/GCH1/LTC4S/PTGS1/NUPR1/UST/BHMT2/TBXAS1/HAAO/SDS/LIPC/THNSL2/GAMT/CH25H/ALOX5AP/OSBPL3/GOT1/EPHX2/ACSM5/ACOX2/ERLIN2/DHRS9/NUP160/CBFA2T3/DDIT4/TECR/DECR2/NUP153/MECR/EGF/IDO1/PGM1/INSR/SLC27A5/NAALAD2/TPR/PRKAG1/MGST3/CYP7B1/GSTM4/PRKAB1/ENO2/NUP50/SLC2A6/UROS/HPGD/SEC13/RANBP2/PFKFB3/SERINC5/GPX4/NFKB1/PFKM/IFNG/APOC1/WDTC1/GATM/ASS1/IGF1/SCD5/NR1H2/SCP2/AKR1C3/PSPH/CPS1/PTGDS/PDGFB/NUP210/ALDH1A3/OAT/NCOR1/NUP43/LPL/SRR/HIF1A/NDC1/OGT/PRKAA1/HAS2/ATP2B4/FA2H/SEPHS1/ALDOC/ACOT8/MCAT/VCAN/EIF6/PYCR1/XBP1/CBR1/PLP1/ALDH18A1/AKR1C4/ABHD2/CHST12/NUP98/ASNS/ADPGK/NUP62	100
BP	GO:0071222	cellular response to lipopolysaccharide	53/2619	205/18670	5.028e-06	0.0002705	0.0002029	TNFAIP3/CXCL9/NFKBIA/CXCL10/TNFRSF1B/CCL5/MAPK3/RIPK2/CXCL13/MALT1/CXCL11/TNIP2/LILRB2/LILRA2/TNIP3/CX3CR1/SERPINE1/CARD8/CDK4/CXCL2/CCR5/TFPI/IRF3/PTPN22/NFKB1/TRIB1/ASS1/TSPO/NOS3/LDOC1/NR1H2/IL6/PLSCR4/GHSR/AXL/DEFA6/MTDH/TNFSF4/HMGB1/LY86/NOD2/CXCL3/SGMS1/AKAP8/PRDX2/IL1RN/CTSG/DEFA5/BCL10/XBP1/CXCL8/CEBPB/SBNO2	53
BP	GO:0019882	antigen processing and presentation	57/2619	226/18670	5.146e-06	0.0002745	0.0002059	TAP1/HLA-C/TREM2/LGMN/HLA-DRB4/SEC24A/HLA-F/HLA-G/HLA-A/RAB27A/LILRB2/PSMB9/RFTN1/CD8A/KIF2A/AP1B1/RACGAP1/DCTN6/DCTN3/CTSF/AP2M1/HLA-B/HLA-E/CAPZA1/HFE/IDE/SEC22B/PSMC2/SEC13/TAPBP/DCTN2/VAMP3/RELB/PSMB6/CENPE/KIF11/CHUK/PSMC3/DYNC1I1/KIF4A/KIF15/HLA-DOB/AP1S1/SLC11A1/HLA-DQB1/DYNC1H1/LNPEP/PSMD8/TAP2/CCR7/NOD2/PSMB5/PSMD10/NOD1/IKBKG/ITGB5/NCF1	57
BP	GO:0001654	eye development	82/2619	362/18670	5.365e-06	0.0002837	0.0002128	MAB21L2/EFEMP1/CRYBB1/PTN/DIO3/WNT5B/SOX9/LAMC3/TMEM231/NIPBL/SMAD3/LIMK2/TMOD1/SLC7A11/FOXC1/SOS1/MDM1/RBP4/IMPDH2/AGTPBP1/EGFR/CRYBG3/SMARCD3/MERTK/NTRK2/CDK4/SCO2/MYOM2/BCL11B/RXRA/BMP4/FAT1/MED1/BBS4/B9D1/FKBP8/NAGLU/GPM6A/JMJD6/CRYAB/TCIRG1/ROM1/OSR2/ARID1A/ATF6/LRP5/PRKCI/CDKN1C/CHRDL1/SIPA1L3/PRDM1/VEGFA/TGIF2/IFT140/ALDH1A3/ARHGAP35/TSKU/TENM3/RS1/IRX5/NINJ1/PRPH2/PFDN5/PHACTR4/HIF1A/HDAC1/NF2/ATP2B4/SIX6/SIX3/MAF/COL4A1/CEP290/RING1/DSCAM/SERPINF1/KERA/MYH10/NRL/ATP2B1/TH/TWIST1	82
BP	GO:0007051	spindle organization	46/2619	170/18670	5.687e-06	0.0002982	0.0002237	PARP3/TUBG2/ASPM/HAUS3/CHEK2/KIF2A/TPX2/UVRAG/RACGAP1/TPR/HAUS2/MAPRE3/SPAG5/DRG1/PRC1/NDC80/DCTN2/EML1/PLK2/CENPE/KIF11/CHMP2A/CCNB1/KIF4A/CLASP1/CDC20/ATRX/TUBGCP5/AURKB/DYNC1H1/BIRC5/TACC2/CHD3/KPNB1/NCOR1/SPAST/SMC1A/CHMP1B/TACC3/MAPRE2/CEP63/SPICE1/FLNA/TUBGCP2/NUP62/FBXO5	46
BP	GO:0071356	cellular response to tumor necrosis factor	69/2619	291/18670	5.771e-06	0.0003002	0.0002251	TNFAIP3/GBP1/AIM2/NFKBIA/GBP2/SFRP1/CEBPA/SPHK1/STAT1/TNFRSF1B/MAP3K5/BIRC3/JAK2/TNFRSF11B/CCL5/MAPK3/CCL18/TRAF1/RORA/PSMB9/PID1/ADAM17/TNFRSF21/CARD8/TNFRSF11A/TNFRSF14/BIRC2/CASP4/MADD/NOL3/ARHGEF2/PLVAP/TNFRSF17/ASAH1/PSMC2/CD40/GPER1/PTPN2/NFKB1/POSTN/CCL8/CD27/PSMB6/CARD14/ASS1/CRHBP/CHUK/PSMC3/XCL1/PSMD8/TNFSF4/PSMB5/TRAF3/CCL13/ZFP36L2/CD58/SGMS1/TNFSF8/PSMD10/HAS2/CYLD/CIB1/IKBKG/TNFSF14/CCL7/TRIM32/CXCL8/PTK2B/CD40LG	69
BP	GO:1901214	regulation of neuron death	73/2619	313/18670	5.883e-06	0.0003024	0.0002268	SIX1/NUPR1/LGMN/NDNF/CD200/TNFRSF1B/MAP3K5/JAK2/CCL5/CRLF1/FIS1/FBXW7/TBK1/ANGPT1/SNCA/CLU/SIGMAR1/HLA-F/TOX3/SLC7A11/DDIT4/ATM/BAD/REL/MAP3K11/PRNP/PINK1/CX3CR1/NQO1/NTRK2/APOE/GSK3B/NTF3/SET/GDF5/FGF20/ROCK1/PPP1R13B/ARRB1/F2R/NTRK1/IFNG/DAXX/PRKCI/TP53BP2/UBE2M/EGR1/EN1/AXL/TYROBP/CASP9/PIN1/UBB/DHCR24/EGLN3/NAIP/MCL1/SOD1/AIMP2/HIF1A/IKBKG/CREB1/TYRO3/ATF2/KRAS/PTK2B/CEBPB/ATF4/SERPINF1/TRIM2/BDNF/DDIT3/PIK3CA	73
BP	GO:0016054	organic acid catabolic process	66/2619	275/18670	5.958e-06	0.0003024	0.0002268	CBS/FAH/HPD/CRYL1/IVD/ALDH7A1/HAAO/SDS/QDPR/THNSL2/GUSB/ECI2/ECHS1/ETFB/DDAH1/GOT1/BCKDHB/ACOX2/PCBD1/GNPDA1/PLA2G15/DECR2/HSD17B10/MECR/DDO/IDO1/BDH2/PHYH/PCCB/SORD/HMGCL/GCAT/ECH1/ASRGL1/HMMR/GSTZ1/PEX7/CD44/HADH/HEXA/PEX2/DDAH2/ECI1/ACAT1/HDC/MPST/DLD/NOS3/SCP2/AHCY/PCK2/ALDH3A2/TXN2/OAT/ACADM/ACOX1/ATP2B4/ACAA2/HNMT/ACOT8/MCAT/CRAT/ALDH6A1/ABHD2/LPIN1/TWIST1	66
BP	GO:0046395	carboxylic acid catabolic process	66/2619	275/18670	5.958e-06	0.0003024	0.0002268	CBS/FAH/HPD/CRYL1/IVD/ALDH7A1/HAAO/SDS/QDPR/THNSL2/GUSB/ECI2/ECHS1/ETFB/DDAH1/GOT1/BCKDHB/ACOX2/PCBD1/GNPDA1/PLA2G15/DECR2/HSD17B10/MECR/DDO/IDO1/BDH2/PHYH/PCCB/SORD/HMGCL/GCAT/ECH1/ASRGL1/HMMR/GSTZ1/PEX7/CD44/HADH/HEXA/PEX2/DDAH2/ECI1/ACAT1/HDC/MPST/DLD/NOS3/SCP2/AHCY/PCK2/ALDH3A2/TXN2/OAT/ACADM/ACOX1/ATP2B4/ACAA2/HNMT/ACOT8/MCAT/CRAT/ALDH6A1/ABHD2/LPIN1/TWIST1	66
BP	GO:0032479	regulation of type I interferon production	37/2619	126/18670	6.069e-06	0.0003055	0.0002291	TNFAIP3/RNF125/STAT1/IRF1/RIPK2/PLCG2/TBK1/LRRFIP1/POLR2L/POLR3C/REL/POLR2E/NMI/POLR2F/IRF3/PTPN22/NFKB1/RELB/TRIM21/CHUK/GPATCH3/MMP12/PIN1/HMGB1/TRAF3/PPM1B/SETD2/CYLD/IFI16/UBE2L6/DDX41/EP300/TRIM32/MYD88/POLR1C/RIOK3/TLR8	37
BP	GO:0010389	regulation of G2/M transition of mitotic cell cycle	51/2619	196/18670	6.178e-06	0.0003086	0.0002314	CDC25B/CETN2/CDC7/TOPBP1/CEP135/CNTRL/SKP1/NBN/NDE1/HAUS3/PSMB9/ATM/SMARCD3/TPX2/DCTN3/CDK4/HAUS2/SFI1/HMMR/PSMC2/USP47/DONSON/FGFR1OP/DCTN2/TUBA4A/PSMB6/PCM1/CCNB1/PSMC3/TAOK1/CLASP1/AURKB/DYNC1H1/PSMD8/RAD51C/DTL/PSMB5/CSNK1E/PSMD10/ALMS1/AKAP9/TAOK3/CDK1/CEP290/CEP63/HSPA2/OFD1/HMGA2/RAD51B/CENPF/FBXO5	51
BP	GO:0045785	positive regulation of cell adhesion	89/2619	403/18670	6.423e-06	0.0003183	0.0002387	SFRP1/DYSF/PTN/NDNF/JAK2/CCL5/ADAM19/PRKD2/BTN2A2/RASGRP1/TFRC/IGFBP2/RIPK2/CXCL13/ANGPT1/MALT1/SMAD3/IL15/HLA-G/IL7R/IL4R/LILRB2/PTPRC/ARL2/ATM/BAD/HSPH1/CTLA4/ITGA5/NCK2/ADA/NEDD9/GSK3B/RUNX3/TNFRSF14/CD83/HLA-E/SOCS1/ERBB2/CD28/ROCK1/ANK3/IL1RL2/CD44/ZAP70/ELANE/MAP3K8/PNP/FOXF1/CD81/CD3E/CD27/IFNG/LCK/ARHGEF7/IGF1/EFNB1/KDR/MAP4K4/IL6/MYOC/XCL1/VEGFA/TNFSF4/HMGB1/CCR7/PRKCQ/NOD2/FERMT1/PPP3CA/NINJ1/EMID1/SPOCK2/EMP2/HAS2/CYLD/CIB1/IL6R/TNFSF14/VNN1/PAK2/BCL10/XBP1/FLNA/PTK2B/CCR2/CD40LG/PODXL/PIK3CA	89
BP	GO:0071219	cellular response to molecule of bacterial origin	54/2619	212/18670	6.606e-06	0.0003221	0.0002416	TNFAIP3/CXCL9/NFKBIA/CXCL10/TREM2/TNFRSF1B/CCL5/MAPK3/RIPK2/CXCL13/MALT1/CXCL11/TNIP2/LILRB2/LILRA2/TNIP3/CX3CR1/SERPINE1/CARD8/CDK4/CXCL2/CCR5/TFPI/IRF3/PTPN22/NFKB1/TRIB1/ASS1/TSPO/NOS3/LDOC1/NR1H2/IL6/PLSCR4/GHSR/AXL/DEFA6/MTDH/TNFSF4/HMGB1/LY86/NOD2/CXCL3/SGMS1/AKAP8/PRDX2/IL1RN/CTSG/DEFA5/BCL10/XBP1/CXCL8/CEBPB/SBNO2	54
BP	GO:0006352	DNA-templated transcription, initiation	61/2619	249/18670	6.655e-06	0.0003221	0.0002416	NOTCH1/SETX/AR/SOX9/MAPK3/RORA/POLR2J/POLR2I/POLR2L/MED13/ATF7IP/NCOA6/BRF2/POLR2E/POLR2F/CTNNBIP1/NOTCH4/CDK4/TAF1D/RXRA/MED1/ZNF451/CDK8/PSMC2/PPARG/POLR2C/POLR1B/MAML1/TAF10/GTF2A2/TBX5/CCNB1/CCNH/PSMC3/NR1H2/NR3C2/TAF9B/POLR2G/RBPJ/TAF7/NR2F1/HMGB1/MED23/MED7/SMARCA5/ERCC2/CREB1/CDK1/MED27/KAT2B/CDKN1A/TFB2M/MNAT1/POLR1C/GTF2H3/BAZ2A/CDK9/NR5A2/GTF3C5/TWIST1/NR1D2	61
BP	GO:0019318	hexose metabolic process	61/2619	249/18670	6.655e-06	0.0003221	0.0002416	AKR1B1/FUCA1/SIK1/PDK2/ENPP1/SDS/GOT1/RORA/ALDH1A1/MPI/G6PC3/RBP4/SLC25A1/BAD/PGM1/SLC35A2/GSK3B/INSR/ATF3/IGFBP4/SORD/FUT1/DYRK2/ENO2/LCMT1/PC/RANBP2/PFKFB3/FAM3A/PTPN2/MAN2B2/PFKM/CHST15/MDH2/POFUT1/WDTC1/LRP5/IGF1/PDK1/NPY1R/PCK2/FUT8/HECTD4/NFE2L1/PDHB/GAA/OGT/PRKAA1/PMM1/ALDOC/KAT2B/SLC25A11/EP300/MDH1/CRY1/FUT4/ATF4/ADPGK/PASK/PIK3CA/SORBS1	61
BP	GO:1900371	regulation of purine nucleotide biosynthetic process	35/2619	117/18670	6.808e-06	0.0003248	0.0002436	PDK2/NUPR1/TREM2/SNCA/NUP160/CBFA2T3/DDIT4/PID1/NUP153/PINK1/INSR/TPR/PRKAG1/NUP50/SLC2A6/GSTZ1/SEC13/RANBP2/PFKFB3/TAZ/GUCA1A/IFNG/IGF1/NOS3/PDK1/NUP210/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/EIF6/NUP98/NUP62	35
BP	GO:0042129	regulation of T cell proliferation	43/2619	156/18670	6.812e-06	0.0003248	0.0002436	IRF1/TNFRSF1B/CCL5/BTN2A2/TFRC/IGFBP2/RIPK2/IL15/HLA-G/PLA2G2D/LILRB2/PTPRC/SOS1/TNFRSF21/CTLA4/IDO1/PRNP/NCK2/TNFRSF14/HLA-E/BMP4/ERBB2/CD28/ZAP70/PNP/CD81/PELI1/CD3E/IGF1/EFNB1/RAC2/IL6/XCL1/TNFSF4/HMGB1/GLMN/PRKCQ/TNFSF8/IL6R/LGALS3/CCR2/CEBPB/CD40LG	43
BP	GO:0033044	regulation of chromosome organization	78/2619	342/18670	6.921e-06	0.0003275	0.0002456	MTF2/JARID2/KDM5A/PRKD2/MAPK3/ERCC1/HNRNPA2B1/SNCA/NBN/NIPBL/ATR/WDR61/DNMT1/TNKS2/CHEK1/TRIP12/ATM/ATF7IP/DLGAP5/NAP1L2/PTTG1/TADA3/PINK1/MKI67/ATAD2B/SART3/SET/TPR/ING2/DDX11/BUB1B/SETD5/LCMT1/ZNHIT1/ZNF451/EID1/KDM3A/SMC5/SETMAR/ARRB1/NDC80/AUTS2/DCP2/CENPE/CCNB1/MYC/PML/TAF7/CDC20/ATRX/HMBOX1/AURKB/VEGFA/HNRNPA1/EED/PRKCQ/RAD50/TOP2A/PAXBP1/SFPQ/RUVBL2/NABP2/AKAP8/OGT/PADI2/TACC3/ATAD2/MNAT1/PIWIL2/UBR5/CDK9/HNRNPD/HMGA1/PTTG2/CENPF/WDR70/TWIST1/FBXO5	78
BP	GO:0050870	positive regulation of T cell activation	52/2619	202/18670	7.021e-06	0.0003297	0.0002473	CCL5/BTN2A2/RASGRP1/TFRC/IGFBP2/RIPK2/MALT1/IL15/HLA-G/IL7R/IL4R/LILRB2/PTPRC/BAD/HSPH1/CTLA4/NCK2/ADA/RUNX3/TNFRSF14/CD83/HLA-E/SOCS1/CD28/IL1RL2/ZAP70/MAP3K8/PNP/CD81/CD3E/CD27/IFNG/LCK/IGF1/EFNB1/IL6/XCL1/TNFSF4/HMGB1/CCR7/PRKCQ/NOD2/CYLD/IL6R/TNFSF14/VNN1/PAK2/BCL10/XBP1/CCR2/CD40LG/PIK3CA	52
BP	GO:1903039	positive regulation of leukocyte cell-cell adhesion	55/2619	218/18670	7.396e-06	0.0003441	0.0002581	CCL5/BTN2A2/RASGRP1/TFRC/IGFBP2/RIPK2/MALT1/IL15/HLA-G/IL7R/IL4R/LILRB2/PTPRC/BAD/HSPH1/CTLA4/NCK2/ADA/RUNX3/TNFRSF14/CD83/HLA-E/SOCS1/CD28/IL1RL2/CD44/ZAP70/ELANE/MAP3K8/PNP/CD81/CD3E/CD27/IFNG/LCK/IGF1/EFNB1/IL6/XCL1/TNFSF4/HMGB1/CCR7/PRKCQ/NOD2/HAS2/CYLD/IL6R/TNFSF14/VNN1/PAK2/BCL10/XBP1/CCR2/CD40LG/PIK3CA	55
BP	GO:0009615	response to virus	75/2619	326/18670	7.436e-06	0.0003441	0.0002581	TNFAIP3/CXCL9/GBP1/AIM2/RNF125/CXCL10/IRAK3/STAT1/IRF1/BIRC3/CCL5/ADAR/TBK1/CLU/FAM111A/IL15/MICB/TRIM22/PTPRC/DDIT4/POLR3C/BAD/PUM2/APOBEC3C/BIRC2/HTRA1/TSPAN6/RNASE2/PENK/PRF1/SAMHD1/RRP1B/IRF3/ZC3HAV1/PIM2/FGR/ISG20/CD40/CXCR4/SERINC5/PRKRA/HSPB1/CCL8/IFNG/BANF1/MAPK11/CHUK/IL6/GPATCH3/PML/APOBEC3B/XCL1/AP1S1/MMP12/TNFSF4/TRAF3/AGBL5/PPM1B/IFITM2/DNAJC3/DDX1/DDX60/SETD2/IFI16/DDX21/IKBKG/SEC14L1/OAS2/RIOK3/FLNA/TLR8/EXOC1/HMGA1/HMGA2/TSPAN32	75
BP	GO:1902749	regulation of cell cycle G2/M phase transition	54/2619	213/18670	7.66e-06	0.0003519	0.0002639	CDC25B/CETN2/CDC7/TOPBP1/CEP135/CNTRL/SKP1/NBN/NDE1/HAUS3/PSMB9/CHEK1/ATM/SMARCD3/TPX2/DCTN3/CDK4/HAUS2/SFI1/HMMR/PSMC2/USP47/DONSON/FGFR1OP/DCTN2/TUBA4A/PSMB6/PCM1/CCNB1/PSMC3/TAOK1/CLASP1/AURKB/DYNC1H1/PSMD8/RAD51C/DTL/PSMB5/CSNK1E/PSMD10/ALMS1/AKAP9/TAOK3/BABAM1/GTSE1/CDK1/CEP290/CEP63/HSPA2/OFD1/HMGA2/RAD51B/CENPF/FBXO5	54
BP	GO:0048880	sensory system development	83/2619	371/18670	7.788e-06	0.0003552	0.0002664	MAB21L2/EFEMP1/CRYBB1/PTN/DIO3/WNT5B/SOX9/LAMC3/TMEM231/NIPBL/SMAD3/LIMK2/TMOD1/SLC7A11/FOXC1/SOS1/MDM1/SEMA3A/RBP4/IMPDH2/AGTPBP1/EGFR/CRYBG3/SMARCD3/MERTK/NTRK2/CDK4/SCO2/MYOM2/BCL11B/RXRA/BMP4/FAT1/MED1/BBS4/B9D1/FKBP8/NAGLU/GPM6A/JMJD6/CRYAB/TCIRG1/ROM1/OSR2/ARID1A/ATF6/LRP5/PRKCI/CDKN1C/CHRDL1/SIPA1L3/PRDM1/VEGFA/TGIF2/IFT140/ALDH1A3/ARHGAP35/TSKU/TENM3/RS1/IRX5/NINJ1/PRPH2/PFDN5/PHACTR4/HIF1A/HDAC1/NF2/ATP2B4/SIX6/SIX3/MAF/COL4A1/CEP290/RING1/DSCAM/SERPINF1/KERA/MYH10/NRL/ATP2B1/TH/TWIST1	83
BP	GO:0150063	visual system development	82/2619	366/18670	8.322e-06	0.0003748	0.0002811	MAB21L2/EFEMP1/CRYBB1/PTN/DIO3/WNT5B/SOX9/LAMC3/TMEM231/NIPBL/SMAD3/LIMK2/TMOD1/SLC7A11/FOXC1/SOS1/MDM1/RBP4/IMPDH2/AGTPBP1/EGFR/CRYBG3/SMARCD3/MERTK/NTRK2/CDK4/SCO2/MYOM2/BCL11B/RXRA/BMP4/FAT1/MED1/BBS4/B9D1/FKBP8/NAGLU/GPM6A/JMJD6/CRYAB/TCIRG1/ROM1/OSR2/ARID1A/ATF6/LRP5/PRKCI/CDKN1C/CHRDL1/SIPA1L3/PRDM1/VEGFA/TGIF2/IFT140/ALDH1A3/ARHGAP35/TSKU/TENM3/RS1/IRX5/NINJ1/PRPH2/PFDN5/PHACTR4/HIF1A/HDAC1/NF2/ATP2B4/SIX6/SIX3/MAF/COL4A1/CEP290/RING1/DSCAM/SERPINF1/KERA/MYH10/NRL/ATP2B1/TH/TWIST1	82
BP	GO:0030808	regulation of nucleotide biosynthetic process	35/2619	118/18670	8.387e-06	0.0003748	0.0002811	PDK2/NUPR1/TREM2/SNCA/NUP160/CBFA2T3/DDIT4/PID1/NUP153/PINK1/INSR/TPR/PRKAG1/NUP50/SLC2A6/GSTZ1/SEC13/RANBP2/PFKFB3/TAZ/GUCA1A/IFNG/IGF1/NOS3/PDK1/NUP210/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/EIF6/NUP98/NUP62	35
BP	GO:0050851	antigen receptor-mediated signaling pathway	73/2619	316/18670	8.399e-06	0.0003748	0.0002811	GBP1/HLA-DRB4/PRKD2/BTN2A2/RIPK2/PLCG2/SH2B2/SKP1/MALT1/BTN2A1/PRKCB/PTPRC/CD38/PSMB9/RFTN1/ITK/TNFRSF21/CTLA4/PRNP/PRKCH/ADA/LAX1/BTN3A3/IGHM/PTPN22/PSMC2/CD28/DENND1B/PLEKHA1/PTPN2/RC3H2/ZAP70/CD81/NFKB1/TRBC1/CD3E/LCK/PSMB6/TRAT1/CHUK/PIK3CB/PSMC3/CD3D/TRAC/TXK/CD247/CD19/HLA-DQB1/PSMD8/CCR7/PRKCQ/THEMIS2/PSMB5/IGLL5/IGLC1/LAT/PSMD10/LIME1/BTN3A1/CYLD/ERMAP/PIK3CD/IKBKG/PAK2/LGALS3/BCL10/CD3G/MS4A1/LCP2/STOML2/BTNL2/LPXN/PIK3CA	73
BP	GO:0006625	protein targeting to peroxisome	24/2619	68/18670	8.715e-06	0.0003789	0.0002842	ECI2/PEX10/EPHX2/ACOX2/PEX19/DECR2/DDO/PHYH/IDE/HMGCL/ECH1/PEX7/CAT/PEX2/SCP2/UBB/PEX12/PEX14/USP9X/ACOX1/AGPS/ACOT8/MPV17/CRAT	24
BP	GO:0072662	protein localization to peroxisome	24/2619	68/18670	8.715e-06	0.0003789	0.0002842	ECI2/PEX10/EPHX2/ACOX2/PEX19/DECR2/DDO/PHYH/IDE/HMGCL/ECH1/PEX7/CAT/PEX2/SCP2/UBB/PEX12/PEX14/USP9X/ACOX1/AGPS/ACOT8/MPV17/CRAT	24
BP	GO:0072663	establishment of protein localization to peroxisome	24/2619	68/18670	8.715e-06	0.0003789	0.0002842	ECI2/PEX10/EPHX2/ACOX2/PEX19/DECR2/DDO/PHYH/IDE/HMGCL/ECH1/PEX7/CAT/PEX2/SCP2/UBB/PEX12/PEX14/USP9X/ACOX1/AGPS/ACOT8/MPV17/CRAT	24
BP	GO:0001822	kidney development	66/2619	278/18670	8.73e-06	0.0003789	0.0002842	SIX1/AKR1B1/HOXA11/SFRP1/NOTCH1/STAT1/SOX9/CRLF1/PGF/ARL3/ANGPT1/NIPBL/SMAD3/CFLAR/FOXC1/NUP160/SDC1/NLE1/CTNNBIP1/ANGPT2/PRKX/PECAM1/BMP4/WNT11/MAGI2/HPGD/KLHL3/GCNT3/LAMA5/JMJD6/CAT/OSR2/APAF1/ACAT1/AGT/ASS1/MPST/SIX2/MYC/CDKN1C/EGR1/PDGFB/EPHA4/CASP9/VEGFA/CA2/PLCE1/MAGED1/CXCR2/TMED10/AQP2/HAS2/IL6R/ID2/ID3/MPV17/CEP290/HOXC11/SGPL1/SMO/GPR4/SERPINF1/KANK2/APH1A/CENPF/PODXL	66
BP	GO:0006367	transcription initiation from RNA polymerase II promoter	49/2619	188/18670	8.861e-06	0.0003819	0.0002865	NOTCH1/AR/SOX9/RORA/POLR2J/POLR2I/POLR2L/MED13/ATF7IP/POLR2E/POLR2F/CTNNBIP1/NOTCH4/CDK4/RXRA/MED1/ZNF451/CDK8/PSMC2/PPARG/POLR2C/MAML1/TAF10/GTF2A2/TBX5/CCNB1/CCNH/PSMC3/NR1H2/NR3C2/TAF9B/POLR2G/RBPJ/TAF7/NR2F1/HMGB1/MED23/MED7/ERCC2/CREB1/CDK1/MED27/KAT2B/CDKN1A/MNAT1/GTF2H3/CDK9/NR5A2/NR1D2	49
BP	GO:0032606	type I interferon production	37/2619	128/18670	9.042e-06	0.0003871	0.0002903	TNFAIP3/RNF125/STAT1/IRF1/RIPK2/PLCG2/TBK1/LRRFIP1/POLR2L/POLR3C/REL/POLR2E/NMI/POLR2F/IRF3/PTPN22/NFKB1/RELB/TRIM21/CHUK/GPATCH3/MMP12/PIN1/HMGB1/TRAF3/PPM1B/SETD2/CYLD/IFI16/UBE2L6/DDX41/EP300/TRIM32/MYD88/POLR1C/RIOK3/TLR8	37
BP	GO:0051196	regulation of coenzyme metabolic process	30/2619	95/18670	9.283e-06	0.0003947	0.0002961	PDK2/NUPR1/SNCA/NUP160/CBFA2T3/DDIT4/ME2/NUP153/INSR/TPR/PRKAG1/NUP50/SLC2A6/GSTZ1/SEC13/RANBP2/PFKFB3/IFNG/IGF1/PDK1/NUP210/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/EIF6/NUP98/NUP62	30
BP	GO:0009132	nucleoside diphosphate metabolic process	43/2619	158/18670	9.667e-06	0.0004083	0.0003062	NUPR1/NME4/NME7/NUP160/CBFA2T3/DDIT4/ENTPD4/NME5/BAD/NUP153/PGM1/INSR/TPR/PRKAG1/ENO2/NUP50/NME3/SLC2A6/NUDT9/SEC13/AK1/RANBP2/PFKFB3/PFKM/IFNG/IGF1/GUK1/NUP210/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/SUCLG1/MPP1/TJP2/ALDOC/EIF6/AMPD3/NUP98/ADPGK/NUP62	43
BP	GO:0034612	response to tumor necrosis factor	72/2619	312/18670	1.003e-05	0.0004208	0.0003157	TNFAIP3/GCH1/GBP1/AIM2/NFKBIA/GBP2/SFRP1/CEBPA/SPHK1/STAT1/TNFRSF1B/MAP3K5/BIRC3/JAK2/TNFRSF11B/CCL5/MAPK3/CCL18/TRAF1/RORA/PSMB9/PID1/ADAM17/TNFRSF21/CARD8/TNFRSF11A/TNFRSF14/BIRC2/CASP4/MADD/NOL3/ARHGEF2/PLVAP/SELE/TNFRSF17/ASAH1/PSMC2/CD40/GPER1/PTPN2/NFKB1/POSTN/CCL8/CD27/PSMB6/CARD14/ASS1/CRHBP/CHUK/PSMC3/XCL1/PSMD8/TNFSF4/YTHDC2/PSMB5/TRAF3/CCL13/ZFP36L2/CD58/SGMS1/TNFSF8/PSMD10/HAS2/CYLD/CIB1/IKBKG/TNFSF14/CCL7/TRIM32/CXCL8/PTK2B/CD40LG	72
BP	GO:0062012	regulation of small molecule metabolic process	98/2619	459/18670	1.013e-05	0.000422	0.0003165	SIK1/PDK2/NUPR1/TREM2/CD320/COX7A1/ENPP1/SNCA/PMVK/RORA/EPHX2/ERLIN2/SLC7A11/NUP160/PSMB9/CBFA2T3/DDIT4/PID1/PTH1R/ME2/BAD/NUP153/EGF/COMT/PINK1/NQO1/APOE/GSK3B/INSR/TPR/IGFBP4/KIT/PRKAG1/DYRK2/NUP50/SLC2A6/LCMT1/GSTZ1/PSMC2/PPARG/SEC13/RANBP2/PFKFB3/GPER1/FAM3A/SC5D/TAZ/GUCA1A/PTPN2/NFKB1/IFNG/APOC1/PSMB6/WDTC1/MBTPS1/TSPO/IGF1/NOS3/CCNB1/PSMC3/NR1H2/GHSR/EGR1/AKR1C3/PDK1/PDGFB/NUP210/PSMD8/PSMB5/DHCR7/KPNB1/NFE2L1/NCOR1/SOD1/NUP43/PSMD10/HIF1A/NDC1/OGT/PRKAA1/HAS2/ATP2B4/CDK1/KAT2B/EIF6/EP300/CRY1/FABP3/PTK2B/NFYC/NUP98/LMF1/OAZ3/TWIST1/PASK/MVK/NUP62/SORBS1	98
BP	GO:0001780	neutrophil homeostasis	10/2619	16/18670	1.033e-05	0.000426	0.0003195	SLC7A11/MERTK/PIK3CB/IL6/AXL/HMGB1/CXCR2/PIK3CD/SH2B3/CCR2	10
BP	GO:0048002	antigen processing and presentation of peptide antigen	49/2619	189/18670	1.036e-05	0.000426	0.0003195	TAP1/HLA-C/TREM2/LGMN/HLA-DRB4/SEC24A/HLA-F/HLA-G/HLA-A/PSMB9/KIF2A/AP1B1/RACGAP1/DCTN6/DCTN3/CTSF/AP2M1/HLA-B/HLA-E/CAPZA1/HFE/IDE/SEC22B/PSMC2/SEC13/TAPBP/DCTN2/VAMP3/PSMB6/CENPE/KIF11/CHUK/PSMC3/DYNC1I1/KIF4A/KIF15/HLA-DOB/AP1S1/SLC11A1/HLA-DQB1/DYNC1H1/LNPEP/PSMD8/TAP2/PSMB5/PSMD10/IKBKG/ITGB5/NCF1	49
BP	GO:0002791	regulation of peptide secretion	105/2619	500/18670	1.057e-05	0.0004289	0.0003217	TNFAIP3/GBP1/AIM2/SFRP1/TREM2/CD200/TNFRSF1B/JAK2/CCL5/RPH3AL/BTN2A2/RASGRP1/IL27RA/MAPK3/RIPK2/SEC24A/ANGPT1/SRI/SLC25A4/SYT11/ARFIP1/IL4R/MPC2/CD38/ARL2/LILRA2/RBP4/BAD/EGFR/TNFRSF21/NLRP1/CARD8/APOE/TNFRSF14/HLA-E/SOCS1/HFE/DNAJC1/EFNA5/HTR2B/IRF3/PTPN22/RAB11FIP1/CRTAM/FGR/CD40/PTGER4/GPER1/TCIRG1/ARRB1/F2R/HADH/POSTN/OXCT1/IFNG/ITPR2/SIRT3/WLS/MAPK11/CRHBP/CHUK/LRP5/IGF1/MAP4K4/ANG/IL6/GHSR/TLR5/PML/ARL2BP/MMP12/IL17RB/TNFSF4/HMGB1/GLMN/ABCC8/CCR7/NOD2/ANO1/FERMT1/PPP3CA/SSTR5/CD58/LPL/HIF1A/IL17RC/TARDBP/CD2/GSDMD/CACNA1D/RHBDF2/FCN1/TCF7L2/ENSA/GOLPH3/XBP1/INHBB/TLR8/CD40LG/EXOC1/MYH10/IL17RA/TWIST1/PASK/SRGN	105
BP	GO:0015980	energy derivation by oxidation of organic compounds	67/2619	285/18670	1.059e-05	0.0004289	0.0003217	PPP1R3C/ENPP1/NDUFC1/SNCA/ETFB/SDHC/NDUFA13/NDUFS4/CBFA2T3/PID1/ME2/NDUFB4/PGM1/PINK1/NDUFA4/UQCR10/IREB2/NDUFA8/GSK3B/INSR/BLOC1S1/IDE/DYRK2/CYC1/COX6C/COX8A/NDUFA2/TAZ/PYGM/CAT/COX6A1/NDUFB6/MDH2/IFNG/NDUFB7/SDHD/SIRT3/FASTKD1/DLD/IGF1/CCNB1/NDUFB2/MYC/NDUFA6/TRAP1/COX5B/NDUFA10/NDUFB11/COQ9/HIF1A/PDHB/GAA/NDUFB8/NDUFA3/UQCRQ/SUCLG1/NDUFS3/CDK1/NDUFS7/NDUFS6/MDH1/NDUFA1/FH/UQCRC1/PASK/PIK3CA/SORBS1	67
BP	GO:0097529	myeloid leukocyte migration	53/2619	210/18670	1.063e-05	0.0004289	0.0003217	SLAMF8/CXCL9/DYSF/CXCL10/TREM2/LGMN/CD200/CCL5/MAPK3/CXCL13/PGF/THBS4/CCL18/CXCL11/CX3CR1/SERPINE1/TNFRSF11A/PECAM1/CXCL2/KIT/CREB3/PLA2G7/PTGER4/CD81/CCL8/RAC2/NBL1/IL6/IRAK4/PDGFB/XCL1/VEGFA/P2RX4/HMGB1/CCR7/CXCL3/CXCR2/SCG2/CCL13/IL17RC/IL1RN/PIK3CD/IL6R/MPP1/S100A12/LGALS3/CXADR/CCL7/CXCL8/PTK2B/CCR2/IL17RA/VEGFB	53
BP	GO:0071347	cellular response to interleukin-1	47/2619	179/18670	1.085e-05	0.0004347	0.0003261	GBP1/NFKBIA/GBP2/SFRP1/IRAK3/SOX9/CCL5/MAPK3/RIPK2/SKP1/CCL18/RORA/TNIP2/PSMB9/TFPI/PSMC2/IL1RL2/TOLLIP/MAP3K8/NFKB1/PELI1/CCL8/PSMB6/MAPK11/CHUK/PSMC3/IL6/EGR1/VRK2/IRAK4/XCL1/PSMD8/UBB/NOD2/PSMB5/MAP3K3/CCL13/PSMD10/HIF1A/HAS2/IL1RN/NOD1/IKBKG/CCL7/MYD88/CXCL8/CEBPB	47
BP	GO:0045862	positive regulation of proteolysis	81/2619	363/18670	1.103e-05	0.0004393	0.0003295	AIM2/NUPR1/CEBPA/FAM162A/TREM2/LGMN/TNFRSF1B/MAP3K5/DAP/JAK2/FIS1/FBXW7/MAPK3/RIPK2/SNCA/CLU/MALT1/SMAD3/FAS/HERPUD1/TNIP1/NDUFA13/CFLAR/CRADD/PCOLCE/CBFA2T3/BAD/EGF/NLRP1/PINK1/CARD8/APOE/GSK3B/SART3/CHFR/CASP4/SPON1/RCN3/PSMC2/ASPH/CYFIP2/PPARG/PHB/GPER1/ARRB1/CLN6/F2R/CR1/IFNG/LCK/PLK2/APAF1/TRIB1/DET1/PCOLCE2/MYC/PML/EPHA4/CSNK1A1/CASP9/RNF19B/CASP8AP2/HMGB1/MTCH1/EGLN3/CSNK1E/ARL6IP5/EDEM1/GRAMD4/CIDEB/PSMD10/OGT/IFI16/NOD1/NGFR/RNF14/HIP1R/BCL10/FBLN1/TRIM32/PTK2B	81
BP	GO:0030522	intracellular receptor signaling pathway	66/2619	280/18670	1.12e-05	0.0004422	0.0003317	TNFAIP3/NFKBIA/SFRP1/RNF125/AR/BIRC3/JAK2/RIPK2/UFSP2/RORA/DHRS3/NCOA3/EZH2/NCOA6/TADA3/PUM2/PIM1/BIRC2/PRAME/TSPAN6/RXRA/CYP7B1/DNAJA1/MED1/IRF3/PTPN22/PPARG/ALPK1/KDM3A/PHB/GPER1/ARID1A/YWHAH/LMO3/DAXX/ASXL2/NR1H2/AKR1C3/GPATCH3/PML/TAF7/BUD31/TRIM24/NR2F1/UBB/NOD2/KAT5/NCOR1/DDX60/HDAC1/CYLD/PADI2/NOD1/IKBKG/SEC14L1/RNF14/FHL2/EP300/CRY1/RIOK3/UBR5/NR5A2/KANK2/TWIST1/RNF34/NR1D2	66
BP	GO:0072522	purine-containing compound biosynthetic process	72/2619	313/18670	1.127e-05	0.0004422	0.0003317	PDK2/NUPR1/TREM2/NME4/NME7/SNCA/MPC2/NUP160/CBFA2T3/DDIT4/PID1/TECR/IMPDH2/SLC25A1/NME5/NUP153/ADK/PGM1/PINK1/ADA/INSR/ACSL5/TPR/PRKAG1/ENO2/NUP50/DGUOK/NME3/SLC2A6/GSTZ1/CYC1/SEC13/AK1/RANBP2/PFKFB3/TAZ/GUCA1A/PNP/PFKM/IFNG/NPR2/ACAT1/DLD/IGF1/NOS3/SCD5/ADCY1/PDK1/GUK1/NUP210/COX5B/NCOR1/NUP43/HIF1A/PDHB/NDC1/OGT/PRKAA1/ADCY2/ALDOC/PANK3/NT5E/EIF6/PRPS1/MPC1/PRPS2/STOML2/AMPD3/NUP98/PAPSS1/ADPGK/NUP62	72
BP	GO:0034599	cellular response to oxidative stress	70/2619	302/18670	1.131e-05	0.0004422	0.0003317	TNFAIP3/GCH1/PDK2/SPHK1/SETX/MAP3K5/JAK2/ECT2/FBXW7/MAPK3/FBLN5/SNCA/SIGMAR1/CCNA2/SLC7A11/CFLAR/HGF/EZH2/NME5/BRF2/EGFR/PINK1/NQO1/GPX3/PRDX6/MAPK7/PENK/NOL3/PLEKHA1/GPX1/CAT/PRKRA/HSPB1/MSRA/PRR5L/CHUK/ANKZF1/NOS3/IL6/VRK2/AKR1C3/PML/PDK1/AXL/TRAP1/MELK/MSRB2/PLA2R1/FUT8/ARL6IP5/SFPQ/MCL1/NFE2L1/PTPRK/SOD1/NET1/HIF1A/PRDX2/PRKAA1/CDK1/VNN1/MPV17/PYCR1/TXNRD2/HNRNPD/ATF4/PSAP/ALDH3B1/STAU1/NCF1	70
BP	GO:0045580	regulation of T cell differentiation	39/2619	139/18670	1.139e-05	0.0004424	0.0003318	IRF1/BTN2A2/RASGRP1/RIPK2/MALT1/IL15/HLA-G/IL7R/IL4R/LILRB2/PTPRC/SOS1/BAD/CTLA4/ADA/RUNX3/CD83/SOCS1/BMP4/ERBB2/CD28/IL1RL2/PTPN2/RC3H2/ZAP70/PNP/CR1/CD27/IFNG/PRDM1/TNFSF4/HMGB1/SOD1/PRDX2/CYLD/CD2/VNN1/XBP1/CCR2	39
BP	GO:0051092	positive regulation of NF-kappaB transcription factor activity	41/2619	149/18670	1.154e-05	0.0004424	0.0003318	AIM2/SPHK1/IRAK3/AR/PRKD2/RIPK2/CLU/LRRFIP1/TRAF1/MALT1/PRKCB/TRIM22/TRAF5/CFLAR/CX3CR1/TNFRSF11A/PRKCH/ARHGEF2/CD40/CAT/NFKB1/NTRK1/CARD14/AGT/CHUK/PRKCI/TRIM52/IRAK4/MTDH/UBB/PRKCQ/NOD2/CIB1/NOD1/IKBKG/S100A12/BCL10/TRIM32/MYD88/KRAS/CD40LG	41
BP	GO:2001056	positive regulation of cysteine-type endopeptidase activity	41/2619	149/18670	1.154e-05	0.0004424	0.0003318	AIM2/FAM162A/LGMN/MAP3K5/DAP/JAK2/FIS1/RIPK2/SNCA/MALT1/SMAD3/FAS/NDUFA13/CRADD/BAD/NLRP1/CARD8/CASP4/ASPH/CYFIP2/PPARG/GPER1/ARRB1/F2R/LCK/APAF1/MYC/PML/CASP9/CASP8AP2/HMGB1/MTCH1/EGLN3/ARL6IP5/GRAMD4/CIDEB/IFI16/NOD1/NGFR/HIP1R/BCL10	41
BP	GO:0043574	peroxisomal transport	24/2619	69/18670	1.16e-05	0.0004424	0.0003318	ECI2/PEX10/EPHX2/ACOX2/PEX19/DECR2/DDO/PHYH/IDE/HMGCL/ECH1/PEX7/CAT/PEX2/SCP2/UBB/PEX12/PEX14/USP9X/ACOX1/AGPS/ACOT8/MPV17/CRAT	24
BP	GO:0005996	monosaccharide metabolic process	68/2619	292/18670	1.274e-05	0.0004829	0.0003622	FGGY/AKR1B1/SLC2A3/FUCA1/SIK1/PDK2/CRYL1/ENPP1/SDS/RBKS/GOT1/RORA/ALDH1A1/MPI/G6PC3/RBP4/SLC25A1/BAD/PGM1/SLC35A2/GSK3B/INSR/ATF3/IGFBP4/SORD/FUT1/DYRK2/ENO2/LCMT1/PC/RANBP2/PFKFB3/FAM3A/PTPN2/MAN2B2/PFKM/CHST15/MDH2/POFUT1/WDTC1/LRP5/IGF1/UGT2B17/PDK1/NPY1R/PCK2/FUT8/HECTD4/NFE2L1/PDHB/GAA/OGT/PRKAA1/CYB5R3/PMM1/ALDOC/KAT2B/SLC25A11/EP300/MDH1/CRY1/FUT4/ATF4/RPE/ADPGK/PASK/PIK3CA/SORBS1	68
BP	GO:0007052	mitotic spindle organization	32/2619	106/18670	1.349e-05	0.0005085	0.0003814	PARP3/TUBG2/CHEK2/KIF2A/TPX2/RACGAP1/TPR/DRG1/PRC1/NDC80/DCTN2/EML1/PLK2/CENPE/KIF11/CHMP2A/CCNB1/KIF4A/CLASP1/CDC20/AURKB/DYNC1H1/BIRC5/TACC2/KPNB1/SPAST/SMC1A/CHMP1B/TACC3/SPICE1/FLNA/NUP62	32
BP	GO:0072330	monocarboxylic acid biosynthetic process	77/2619	343/18670	1.437e-05	0.0005385	0.0004039	HPGDS/LTC4S/PTGS1/NUPR1/UST/TBXAS1/SDS/LIPC/THNSL2/CH25H/ALOX5AP/OSBPL3/EPHX2/ACSM5/ACOX2/ERLIN2/DHRS9/NUP160/CBFA2T3/DDIT4/TECR/DECR2/NUP153/MECR/IDO1/PGM1/INSR/SLC27A5/TPR/PRKAG1/CYP7B1/GSTM4/PRKAB1/ENO2/NUP50/SLC2A6/HPGD/SEC13/RANBP2/PFKFB3/GPX4/PFKM/IFNG/APOC1/WDTC1/IGF1/SCD5/NR1H2/SCP2/AKR1C3/PTGDS/NUP210/ALDH1A3/NCOR1/NUP43/LPL/SRR/HIF1A/NDC1/OGT/PRKAA1/FA2H/ALDOC/ACOT8/MCAT/VCAN/EIF6/XBP1/CBR1/PLP1/AKR1C4/ABHD2/CHST12/NUP98/ASNS/ADPGK/NUP62	77
BP	GO:0051402	neuron apoptotic process	58/2619	239/18670	1.499e-05	0.0005581	0.0004186	SIX1/PIGT/NUPR1/DIO3/FAM162A/LGMN/NDNF/JAK2/CRLF1/FIS1/FBXW7/ANGPT1/SNCA/SIGMAR1/TOX3/ATM/TNFRSF21/MAP3K11/NLRP1/PRNP/PINK1/CX3CR1/NQO1/NTRK2/APOE/NTF3/SET/GDF5/FGF20/ROCK1/ARRB1/F2R/NTRK1/APAF1/PRKCI/UBE2M/EN1/AXL/TYROBP/CASP9/PIN1/EGLN3/NAIP/MCL1/SOD1/HIF1A/NGFR/TYRO3/ATF2/KRAS/PTK2B/CEBPB/ATF4/TRIM2/HSPA5/BDNF/DDIT3/PIK3CA	58
BP	GO:0070098	chemokine-mediated signaling pathway	28/2619	88/18670	1.556e-05	0.0005758	0.0004319	CXCL9/CXCL10/TREM2/CCL5/CXCL13/CCL18/CXCL11/FOXC1/CX3CR1/CXCL2/CCR5/CXCR4/CCL8/RBM15/XCL1/CCR7/CXCL3/CXCR2/CCL13/HIF1A/PADI2/CIB1/CCL7/SH2B3/CXCL8/PTK2B/CCR2/CXCR6	28
BP	GO:0010506	regulation of autophagy	74/2619	327/18670	1.565e-05	0.0005761	0.0004321	NUPR1/TREM2/DAP/FBXW7/MAPK3/RIPK2/VPS13C/TBK1/SNCA/LAMP3/ATP6V0D1/TRIM22/UCHL1/HGF/ATM/MTMR9/CTSA/BAD/PIKFYVE/UVRAG/PINK1/GSK3B/DRAM1/CAPNS1/RRAGA/PRKAG1/SEC22B/EXOC7/PRKAB1/HERC1/HTR2B/PTPN22/PIM2/FBXL2/ROCK1/POLDIP2/HSPB1/ADRB2/IFNG/PLK2/TRIM21/PIK3CB/TSPO/KDR/TMEM59/RASIP1/NAMPT/MTDH/HMGB1/UBQLN4/ATP6V0E2/ATG13/LAMTOR2/MLST8/OPTN/MCL1/KAT5/HIF1A/TPCN1/PRKAA1/IFI16/CTTN/NOD1/IKBKG/RRAGD/EP300/XBP1/SESN1/NPC1/EXOC1/PSAP/CLEC16A/DDIT3/PIK3CA	74
BP	GO:0010952	positive regulation of peptidase activity	50/2619	197/18670	1.583e-05	0.0005791	0.0004343	AIM2/FAM162A/LGMN/MAP3K5/DAP/JAK2/FIS1/MAPK3/RIPK2/SNCA/MALT1/SMAD3/FAS/NDUFA13/CFLAR/CRADD/PCOLCE/BAD/NLRP1/PINK1/CARD8/CASP4/RCN3/ASPH/CYFIP2/PPARG/GPER1/ARRB1/F2R/CR1/LCK/APAF1/PCOLCE2/MYC/PML/EPHA4/CASP9/CASP8AP2/HMGB1/MTCH1/EGLN3/ARL6IP5/GRAMD4/CIDEB/IFI16/NOD1/NGFR/HIP1R/BCL10/FBLN1	50
BP	GO:0000070	mitotic sister chromatid segregation	41/2619	151/18670	1.636e-05	0.0005935	0.0004451	TUBG2/NIPBL/ATM/DLGAP5/PTTG1/RACGAP1/TPR/BUB1B/NUSAP1/SPAG5/LCMT1/SMC5/NCAPH/CDCA8/CHMP6/KIF18B/PRC1/NDC80/CENPE/CHMP2A/NAA50/CCNB1/NCAPG/MIS12/KIF4A/CDC20/ATRX/AURKB/KPNB1/SMC4/KATNB1/AKAP8/SMC1A/CHMP1B/TACC3/CENPC/PTTG2/CENPF/NUP62/POGZ/FBXO5	41
BP	GO:0006140	regulation of nucleotide metabolic process	40/2619	146/18670	1.641e-05	0.0005935	0.0004451	PDK2/NUPR1/TREM2/COX7A1/SNCA/NUP160/CBFA2T3/DDIT4/PID1/ME2/NUP153/PINK1/INSR/TPR/PRKAG1/NUP50/SLC2A6/GSTZ1/SEC13/RANBP2/PFKFB3/TAZ/GUCA1A/IFNG/TSPO/IGF1/NOS3/CCNB1/PDK1/NUP210/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/CDK1/EIF6/NUP98/NUP62	40
BP	GO:0050730	regulation of peptidyl-tyrosine phosphorylation	61/2619	256/18670	1.668e-05	0.0005999	0.0004499	SFRP1/TREM2/JAK2/CCL5/CRLF1/SEMA4D/FBXW7/RIPK2/THBS4/ANGPT1/IL15/PTPRC/HGF/ADAM17/EGFR/EGF/ITGA5/PRNP/NCK2/NTRK2/RAP2C/NEDD9/TNFRSF14/NTF3/SOCS1/PECAM1/KIT/EFNA5/ARHGEF2/CTF1/CD40/PTPN2/CHMP6/FGFR1OP/CD44/CD81/CBLB/CD3E/IFNG/AGT/IGF1/IL6/HBEGF/EREG/PDGFB/EPHA4/ARL2BP/VEGFA/ABI1/DOCK3/NF2/IL6R/PAK2/GGNBP2/GHR/ERBB4/SH2B3/MVP/PTK2B/BDNF/NCF1	61
BP	GO:0006164	purine nucleotide biosynthetic process	69/2619	300/18670	1.708e-05	0.0006085	0.0004564	PDK2/NUPR1/TREM2/NME4/NME7/SNCA/MPC2/NUP160/CBFA2T3/DDIT4/PID1/TECR/IMPDH2/SLC25A1/NME5/NUP153/ADK/PGM1/PINK1/ADA/INSR/ACSL5/TPR/PRKAG1/ENO2/NUP50/NME3/SLC2A6/GSTZ1/CYC1/SEC13/AK1/RANBP2/PFKFB3/TAZ/GUCA1A/PFKM/IFNG/NPR2/ACAT1/DLD/IGF1/NOS3/SCD5/ADCY1/PDK1/GUK1/NUP210/COX5B/NCOR1/NUP43/HIF1A/PDHB/NDC1/OGT/PRKAA1/ADCY2/ALDOC/PANK3/EIF6/PRPS1/MPC1/PRPS2/STOML2/AMPD3/NUP98/PAPSS1/ADPGK/NUP62	69
BP	GO:0071496	cellular response to external stimulus	76/2619	339/18670	1.712e-05	0.0006085	0.0004564	CBS/SFRP1/SIK1/PDK2/PTN/FOLR1/IRF1/MAP3K5/DAP/SOX9/MAPK3/GABARAPL1/IL15/FAS/GABARAPL2/GOT1/CRADD/PTPRC/CHEK1/BAD/SLC38A2/EGFR/COMT/BAIAP2/PIM1/ATF3/RRAGA/HFE/PENK/WNT11/PIK3C2B/MED1/PPARG/KCNJ2/CD40/PTGER4/NFKB1/POSTN/FOLR2/AGT/TBL2/AKR1C3/TLR5/AXL/NAMPT/TRIM24/HNRNPA1/TXN2/P2RX4/CASP8AP2/ARHGAP35/SOD1/WRN/LPL/AQP2/PRKAA1/IFI16/GSDMD/TNFSF14/RRAGD/BCL10/CDKN1A/XBP1/MYD88/ASGR1/SESN1/INHBB/TLR8/ATF4/KANK2/HSPA5/GABARAP/BCL11A/ASNS/CLEC16A/ATP2B1	76
BP	GO:0030595	leukocyte chemotaxis	55/2619	224/18670	1.724e-05	0.000609	0.0004568	SLAMF8/CXCL9/DYSF/CXCL10/PTN/LGMN/CCL5/MAPK3/CXCL13/PGF/THBS4/CH25H/CCL18/CXCL11/GPR183/ADAM17/SERPINE1/TNFRSF11A/CXCL2/KIT/CREB3/CCR5/CYP7B1/PLA2G7/CXCR4/S1PR1/CCL8/RAC2/NBL1/IL6/PDGFB/XCL1/VEGFA/HMGB1/CCR7/CXCL3/CXCR2/SCG2/CCL13/IL17RC/IL1RN/PADI2/PIK3CD/IL6R/TNFSF14/MPP1/S100A12/LGALS3/CXADR/CCL7/CXCL8/PTK2B/CCR2/IL17RA/VEGFB	55
BP	GO:1901293	nucleoside phosphate biosynthetic process	85/2619	390/18670	1.732e-05	0.000609	0.0004568	PDK2/NUPR1/TREM2/NME4/TK2/HAAO/NME7/AGPAT1/SNCA/MPC2/NUP160/CBFA2T3/DDIT4/PID1/TECR/IMPDH2/SLC25A1/NME5/NUP153/ADK/IDO1/PGM1/AGPAT5/PINK1/ADA/INSR/ACSL5/RRM2/TPR/PRKAG1/ENO2/NUP50/DGUOK/NME3/SLC2A6/GSTZ1/CYC1/SEC13/AK1/RANBP2/PFKFB3/TAZ/GUCA1A/PNP/PFKM/IFNG/NPR2/ACAT1/AK6/DLD/IGF1/NOS3/SCD5/ADCY1/PDK1/NAMPT/GUK1/DCTD/NUP210/COX5B/RAD50/NADSYN1/NCOR1/NUP43/HIF1A/PDHB/NDC1/OGT/PRKAA1/CTPS1/SUCLG1/ADCY2/TYMS/ALDOC/PANK3/EIF6/PRPS1/MPC1/PRPS2/STOML2/AMPD3/NUP98/PAPSS1/ADPGK/NUP62	85
BP	GO:0051817	modification of morphology or physiology of other organism involved in symbiotic interaction	33/2619	112/18670	1.748e-05	0.0006113	0.0004585	CCL5/CHD1/SMAD3/TNIP1/BAD/KPNA2/APOE/INSR/RRAGA/RXRA/RRP1B/LEF1/FBXL2/PC/ELANE/CCL8/TUSC2/CTDP1/PSMC3/YTHDC2/KPNB1/MBL2/CCNK/HDAC1/TARDBP/PPIB/CTSG/TYMS/KPNA1/EP300/KPNA3/VAPA/HMGA2	33
BP	GO:0050714	positive regulation of protein secretion	63/2619	268/18670	1.918e-05	0.000667	0.0005003	AIM2/TREM2/JAK2/RPH3AL/RASGRP1/MAPK3/RIPK2/SEC24A/SRI/IL4R/MPC2/CD38/LILRA2/RBP4/BAD/EGFR/NLRP1/CARD8/TNFRSF14/HLA-E/HTR2B/IRF3/PTPN22/CRTAM/FGR/PTGER4/GPER1/ARRB1/F2R/POSTN/OXCT1/IFNG/SIRT3/WLS/MAPK11/CHUK/IGF1/ANG/IL6/MMP12/IL17RB/TNFSF4/HMGB1/GLMN/NOD2/ANO1/FERMT1/CD58/LPL/HIF1A/IL17RC/TARDBP/CD2/GSDMD/FCN1/TCF7L2/GOLPH3/XBP1/TLR8/EXOC1/MYH10/IL17RA/TWIST1	63
BP	GO:1900542	regulation of purine nucleotide metabolic process	39/2619	142/18670	1.957e-05	0.0006743	0.0005058	PDK2/NUPR1/TREM2/COX7A1/SNCA/NUP160/CBFA2T3/DDIT4/PID1/NUP153/PINK1/INSR/TPR/PRKAG1/NUP50/SLC2A6/GSTZ1/SEC13/RANBP2/PFKFB3/TAZ/GUCA1A/IFNG/TSPO/IGF1/NOS3/CCNB1/PDK1/NUP210/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/CDK1/EIF6/NUP98/NUP62	39
BP	GO:0051783	regulation of nuclear division	48/2619	188/18670	1.961e-05	0.0006743	0.0005058	TOM1L1/SPHK1/NIPBL/BTC/CHEK1/ATM/DLGAP5/EGF/PTTG1/MKI67/PRMT5/INSR/TPR/BMP4/BUB1B/NUSAP1/LCMT1/CD28/SMC5/CDC14A/KNTC1/DRG1/NDC80/PHIP/CENPE/KIF11/LRP5/IGF1/CHMP2A/CCNB1/CDKN1C/CDC20/EREG/ATRX/PDGFB/AURKB/PIN1/RAD1/NFE2L1/SMC1A/CHMP1B/TACC3/PIWIL2/PTTG2/CENPF/NUP62/DAZL/FBXO5	48
BP	GO:0006732	coenzyme metabolic process	87/2619	403/18670	2.025e-05	0.0006887	0.0005166	THTPA/GCH1/SLC2A3/PDK2/NUPR1/FOLR1/MTHFD2/BHMT2/HAAO/QDPR/GAMT/RBKS/PEMT/SNCA/PMVK/ACSM5/PCBD1/MPC2/CD38/NUP160/CBFA2T3/DDIT4/TECR/PNPO/ME2/SLC25A1/NUP153/ACOT13/IDO1/PGM1/INSR/ACSL5/PCCB/TPR/MOCS2/PRKAG1/HMGCL/ENO2/NUP50/COQ6/SLC2A6/GSTZ1/PC/SEC13/RANBP2/PFKFB3/GGH/FOLR2/PFKM/MDH2/IFNG/ACAT1/DLD/IGF1/SCD5/PDK1/NAMPT/AHCY/NUP210/NADSYN1/CYP4F11/NCOR1/COQ9/NUP43/HIF1A/PDHB/NDC1/OGT/PRKAA1/CYB5R3/SUCLG1/TYMS/ALDOC/PANK3/ACOT8/VNN1/FAR2/NT5E/EIF6/COQ2/MDH1/MPC1/NUP98/RPE/ADPGK/MVK/NUP62	87
BP	GO:0022407	regulation of cell-cell adhesion	87/2619	403/18670	2.025e-05	0.0006887	0.0005166	IRF1/SOCS6/JAK2/CCL5/ADAM19/BTN2A2/RASGRP1/TFRC/IGFBP2/RIPK2/CXCL13/MALT1/IL15/HLA-G/IL7R/PLA2G2D/IL4R/LILRB2/PTPRC/BAD/HSPH1/TNFRSF21/CTLA4/IDO1/PRNP/NCK2/ADA/RUNX3/TNFRSF14/CD83/HLA-E/SOCS1/HFE/MAPK7/LAX1/BMP4/ERBB2/EFNA5/LEF1/PTPN22/CD28/ANK3/IL1RL2/PTPN2/RC3H2/CD44/ZAP70/ELANE/MAP3K8/PNP/CD81/PELI1/CD3E/CD27/IFNG/LCK/ASS1/IGF1/EFNB1/IL6/XCL1/VEGFA/TNFSF4/HMGB1/GLMN/CCR7/PRKCQ/NOD2/TENM3/PRDX2/HAS2/CYLD/IL1RN/NF2/IL6R/TNFSF14/VNN1/PAK2/LGALS3/BCL10/XBP1/SH2B3/CCR2/CEBPB/CD40LG/PODXL/PIK3CA	87
BP	GO:0009165	nucleotide biosynthetic process	84/2619	386/18670	2.054e-05	0.0006948	0.0005211	PDK2/NUPR1/TREM2/NME4/TK2/HAAO/NME7/AGPAT1/SNCA/MPC2/NUP160/CBFA2T3/DDIT4/PID1/TECR/IMPDH2/SLC25A1/NME5/NUP153/ADK/IDO1/PGM1/AGPAT5/PINK1/ADA/INSR/ACSL5/RRM2/TPR/PRKAG1/ENO2/NUP50/DGUOK/NME3/SLC2A6/GSTZ1/CYC1/SEC13/AK1/RANBP2/PFKFB3/TAZ/GUCA1A/PNP/PFKM/IFNG/NPR2/ACAT1/AK6/DLD/IGF1/NOS3/SCD5/ADCY1/PDK1/NAMPT/GUK1/DCTD/NUP210/COX5B/RAD50/NADSYN1/NCOR1/NUP43/HIF1A/PDHB/NDC1/OGT/PRKAA1/CTPS1/ADCY2/TYMS/ALDOC/PANK3/EIF6/PRPS1/MPC1/PRPS2/STOML2/AMPD3/NUP98/PAPSS1/ADPGK/NUP62	84
BP	GO:0034404	nucleobase-containing small molecule biosynthetic process	55/2619	226/18670	2.259e-05	0.0007603	0.0005703	NUPR1/NME4/TK2/ENPP1/NME7/NUP160/CBFA2T3/DDIT4/PDE1A/ENTPD4/IMPDH2/NT5C2/NME5/NUP153/ADK/PGM1/TDG/ADA/INSR/TPR/PRKAG1/SAMHD1/ENO2/NUP50/NME3/SLC2A6/TYMP/NUDT9/GPX1/SEC13/RANBP2/PFKFB3/PNP/PFKM/IFNG/NUDT11/ACAT1/IGF1/GUK1/NUP210/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/DNPH1/CTPS1/ALDOC/NT5E/EIF6/AMPD3/NUP98/ADPGK/NUP62	55
BP	GO:1902175	regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	13/2619	27/18670	2.301e-05	0.0007702	0.0005777	FBXW7/NME5/PINK1/MAPK7/NOL3/GPX1/HSPB1/TRAP1/SFPQ/MCL1/SOD1/HIF1A/VNN1	13
BP	GO:0031056	regulation of histone modification	39/2619	143/18670	2.331e-05	0.0007761	0.0005821	MTF2/JARID2/KDM5A/PRKD2/MAPK3/SNCA/NIPBL/WDR61/DNMT1/CHEK1/TRIP12/ATM/NAP1L2/TADA3/PINK1/SART3/SET/ING2/SETD5/ZNHIT1/ZNF451/EID1/KDM3A/ARRB1/AUTS2/CCNB1/TAF7/ATRX/VEGFA/EED/PAXBP1/RUVBL2/AKAP8/OGT/PIWIL2/UBR5/CDK9/WDR70/TWIST1	39
BP	GO:0032651	regulation of interleukin-1 beta production	28/2619	90/18670	2.479e-05	0.0008211	0.0006159	TNFAIP3/AIM2/SPHK1/TREM2/JAK2/RIPK2/MALT1/SMAD3/LILRA2/NLRP1/CX3CR1/CARD8/F2R/HSPB1/IFNG/IGF1/GHSR/EGR1/PML/TYROBP/HMGB1/CCR7/NOD2/LPL/IFI16/GSDMD/NOD1/TLR8	28
BP	GO:0061458	reproductive system development	92/2619	434/18670	2.5e-05	0.0008238	0.0006179	HOXA11/SFRP1/NUPR1/PTN/NOTCH1/CEBPA/AR/HOXA10/KDM5A/SOX9/ADAM19/MAPK3/ERCC1/NIPBL/ASPM/FOXC1/SERPINA5/TCF7/SDC1/SEMA3A/ARID4B/ATM/RBP4/EGFR/MERTK/BSG/STC1/ADA/INSR/BIRC2/MDFI/KIT/HTRA1/ING2/RXRA/BMP4/CYP7B1/LEF1/MED1/PPARG/PLEKHA1/ARRB1/ARID1A/NTRK1/ID4/RBM15/ZFPM2/NOS3/RAB13/LDOC1/NASP/ANG/CDKN1C/GHSR/BRCA2/AKR1C3/RBPJ/AXL/EREG/ATRX/PDGFB/PRDM1/VEGFA/UBB/DHCR24/IRX5/TMED2/ARID4A/SOD1/PLCD1/HIF1A/TMF1/MEA1/SETD2/BCL2L2/BPTF/GDF9/DAZAP1/GGNBP2/TYRO3/NDUFS6/PATZ1/SGPL1/INHBB/FLNA/CEBPB/SERPINF1/HSPA5/PSAP/STC2/RTCB/EPOR	92
BP	GO:0007031	peroxisome organization	26/2619	81/18670	2.603e-05	0.0008532	0.0006399	FIS1/ECI2/PEX10/EPHX2/ACOX2/PEX19/DECR2/DDO/PHYH/IDE/HMGCL/ECH1/PEX7/PEX11A/CAT/PEX2/SCP2/UBB/PEX12/PEX14/USP9X/ACOX1/AGPS/ACOT8/MPV17/CRAT	26
BP	GO:0051193	regulation of cofactor metabolic process	34/2619	119/18670	2.681e-05	0.0008731	0.0006548	PDK2/NUPR1/SNCA/SLC7A11/NUP160/CBFA2T3/DDIT4/ME2/NUP153/PINK1/INSR/TPR/PRKAG1/NUP50/SLC2A6/GSTZ1/SEC13/RANBP2/PFKFB3/IFNG/IGF1/RAC2/PDK1/NUP210/NCOR1/NUP43/HIF1A/NDC1/PRDX2/OGT/PRKAA1/EIF6/NUP98/NUP62	34
BP	GO:0060326	cell chemotaxis	69/2619	304/18670	2.697e-05	0.0008731	0.0006548	SLAMF8/CXCL9/DYSF/CXCL10/PTN/NOTCH1/LGMN/CCL5/PRKD2/MAPK3/CXCL13/PGF/THBS4/CH25H/CCL18/CXCL11/HGF/GPR183/ADAM17/CX3CR1/SERPINE1/TNFRSF11A/CXCL2/KIT/CREB3/CCR5/CYP7B1/LEF1/PLA2G7/CXCR4/S1PR1/HSPB1/CCL8/ABCC1/RAB13/FGF18/KDR/RAC2/NBL1/IL6/HBEGF/PDGFB/XCL1/VEGFA/P2RX4/HMGB1/CCR7/PRKCQ/CXCL3/CXCR2/SCG2/CCL13/IL17RC/IL1RN/PADI2/PIK3CD/IL6R/TNFSF14/MPP1/S100A12/LGALS3/CXADR/CCL7/CXCL8/PTK2B/CCR2/IL17RA/VEGFB/CXCR6	69
BP	GO:0006109	regulation of carbohydrate metabolic process	51/2619	206/18670	2.705e-05	0.0008731	0.0006548	SIK1/PDK2/NUPR1/ENPP1/SNCA/RORA/NUP160/CBFA2T3/DDIT4/PTH1R/BAD/NUP153/EGF/GSK3B/INSR/TPR/IGFBP4/PRKAG1/DYRK2/NUP50/SLC2A6/LCMT1/SEC13/RANBP2/PFKFB3/GPER1/FAM3A/PTPN2/NFKB1/IFNG/IGF1/PDK1/PDGFB/NUP210/NFE2L1/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/HAS2/KAT2B/EIF6/EP300/CRY1/PTK2B/NUP98/PASK/NUP62/SORBS1	51
BP	GO:0007059	chromosome segregation	72/2619	321/18670	2.768e-05	0.0008888	0.0006667	BEX4/SMC6/SRPK1/ECT2/FBXW7/TUBG2/NDE1/NIPBL/ATM/DLGAP5/PTTG1/UVRAG/PUM2/RACGAP1/ACTR3/MKI67/TPR/UBE2I/DDX11/BUB1B/MMS19/NUSAP1/SPAG5/LCMT1/SMC5/RMI1/NCAPH/CDCA8/CHMP6/KIF18B/PRC1/NDC80/BANF1/CENPE/CHMP2A/NAA50/CCNB1/NCAPG/MIS12/KIF4A/CDC20/TOP1/ATRX/AURKB/DYNC1H1/RAD51C/HJURP/BIRC5/TOP2A/CENPT/MCMBP/SFPQ/KPNB1/SMC4/NUP43/KATNB1/USP9X/AKAP8/SMC1A/NDC1/ERCC2/CHMP1B/TACC3/CENPC/SPICE1/RIOK3/ACTR2/PTTG2/CENPF/NUP62/POGZ/FBXO5	72
BP	GO:0070498	interleukin-1-mediated signaling pathway	30/2619	100/18670	2.832e-05	0.0009047	0.0006785	NFKBIA/IRAK3/MAPK3/RIPK2/SKP1/TNIP2/PSMB9/PSMC2/IL1RL2/TOLLIP/MAP3K8/NFKB1/PELI1/PSMB6/CHUK/PSMC3/IL6/EGR1/VRK2/IRAK4/PSMD8/UBB/NOD2/PSMB5/MAP3K3/PSMD10/IL1RN/NOD1/IKBKG/MYD88	30
BP	GO:0002478	antigen processing and presentation of exogenous peptide antigen	45/2619	175/18670	2.906e-05	0.0009237	0.0006928	TAP1/HLA-C/LGMN/HLA-DRB4/SEC24A/HLA-F/HLA-G/HLA-A/PSMB9/KIF2A/AP1B1/RACGAP1/DCTN6/DCTN3/CTSF/AP2M1/HLA-B/HLA-E/CAPZA1/SEC22B/PSMC2/SEC13/TAPBP/DCTN2/VAMP3/PSMB6/CENPE/KIF11/CHUK/PSMC3/DYNC1I1/KIF4A/KIF15/HLA-DOB/AP1S1/HLA-DQB1/DYNC1H1/LNPEP/PSMD8/TAP2/PSMB5/PSMD10/IKBKG/ITGB5/NCF1	45
BP	GO:0033002	muscle cell proliferation	57/2619	239/18670	3.022e-05	0.0009557	0.0007168	TNFAIP3/SIX1/AKR1B1/NOTCH1/JARID2/STAT1/MAP3K5/JAK2/CCL5/IGFBP5/ANGPT1/IL15/CFLAR/DNMT1/FOXC1/PDE1A/RBP4/ABCC4/EGFR/COMT/CTNNBIP1/PIM1/RXRA/BMP4/FGF20/HPGD/PPARG/GPER1/S1PR1/ELANE/NDRG2/IFNG/TRIB1/ZFPM2/AGT/MAPK11/IGF1/TBX5/CCNB1/ANG/IL6/HBEGF/IRAK4/RBPJ/NAMPT/EREG/PDGFB/PAXBP1/IL6R/CDK1/ID2/TCF7L2/CDKN1A/MNAT1/ERBB4/FOXJ2/TENM4	57
BP	GO:2001242	regulation of intrinsic apoptotic signaling pathway	43/2619	165/18670	3.064e-05	0.0009641	0.0007231	NUPR1/FIS1/FBXW7/CLU/HERPUD1/NDUFA13/BCL2A1/NME5/BAD/NCK2/PINK1/CREB3/MAPK7/ING2/NOL3/ARHGEF2/DNAJA1/HNRNPK/USP47/GPX1/PTPN2/CD44/PRKRA/HSPB1/LCK/TAF9B/TRAP1/UBB/SFPQ/MCL1/SOD1/SGMS1/HIF1A/HDAC1/CYLD/BCL2L2/NDUFS3/RAD9A/VNN1/TRIM32/XBP1/STYXL1/DDIT3	43
BP	GO:0048608	reproductive structure development	91/2619	431/18670	3.234e-05	0.001008	0.000756	HOXA11/SFRP1/NUPR1/PTN/NOTCH1/CEBPA/AR/HOXA10/KDM5A/SOX9/ADAM19/MAPK3/ERCC1/NIPBL/ASPM/FOXC1/SERPINA5/TCF7/SDC1/SEMA3A/ARID4B/ATM/RBP4/EGFR/MERTK/BSG/STC1/ADA/INSR/BIRC2/MDFI/KIT/HTRA1/ING2/RXRA/BMP4/CYP7B1/LEF1/MED1/PPARG/PLEKHA1/ARRB1/ARID1A/NTRK1/ID4/RBM15/ZFPM2/NOS3/RAB13/LDOC1/NASP/ANG/CDKN1C/GHSR/BRCA2/AKR1C3/RBPJ/AXL/EREG/ATRX/PDGFB/PRDM1/VEGFA/UBB/DHCR24/IRX5/TMED2/ARID4A/SOD1/PLCD1/HIF1A/TMF1/MEA1/SETD2/BCL2L2/BPTF/GDF9/DAZAP1/GGNBP2/TYRO3/PATZ1/SGPL1/INHBB/FLNA/CEBPB/SERPINF1/HSPA5/PSAP/STC2/RTCB/EPOR	91
BP	GO:0050777	negative regulation of immune response	40/2619	150/18670	3.244e-05	0.001008	0.000756	SLAMF8/TNFAIP3/IRAK3/PARP3/IL27RA/ADAR/ANGPT1/HLA-F/HLA-G/IL7R/IL4R/PTPRC/NMI/CTLA4/THOC1/TNFRSF14/HLA-E/HFE/SAMHD1/CD96/PPARG/GPX1/FAM3A/PTPN2/RC3H2/FOXF1/CR1/NR1H2/XCL1/MMP12/CUEDC2/TNFSF4/C4BPB/IFI16/TYRO3/LGALS3/COL3A1/IL13RA2/CCR2/CD59	40
BP	GO:0048545	response to steroid hormone	83/2619	385/18670	3.271e-05	0.001008	0.000756	SFRP1/PTN/NOTCH1/AR/JAK2/IGFBP2/UFSP2/GOT1/RORA/CFLAR/CD38/DDIT4/NCOA3/SDC1/HSD11B2/GABRB1/NCOA6/BAD/EGFR/TADA3/STC1/ABCA3/RXRA/BMP4/CYP7B1/DNAJA1/LEF1/MED1/TFPI/PPARG/KDM3A/PHB/GPER1/ARID1A/YWHAH/LMO3/DAXX/ASS1/TSPO/PAPPA/NR1H2/IL6/GHSR/NR3C2/AKR1C3/TAF7/ABCA2/CPS1/PCK2/BUD31/CASP9/CA2/USP8/NR2F1/CALCR/SSTR5/KAT5/ZFP36L2/PGRMC2/NCOR1/HDAC1/IL1RN/PADI2/TYMS/AKAP13/RNF14/HNMT/FHL2/CDKN1A/EP300/CRY1/KRAS/UBR5/CSN1S1/NPC1/ABHD2/NR5A2/SERPINF1/KANK2/IL22/ATP2B1/TH/NR1D2	83
BP	GO:0006119	oxidative phosphorylation	39/2619	145/18670	3.283e-05	0.001008	0.000756	NUPR1/COX7A1/NDUFC1/SNCA/SDHC/NDUFA13/NDUFS4/NDUFB4/PINK1/NDUFA4/UQCR10/NDUFA8/CYC1/COX6C/COX8A/NDUFA2/TAZ/COX6A1/NDUFB6/NDUFB7/SDHD/DLD/CCNB1/NDUFB2/NDUFA6/COX5B/NDUFA10/NDUFB11/COQ9/NDUFB8/NDUFA3/UQCRQ/NDUFS3/CDK1/NDUFS7/NDUFS6/STOML2/NDUFA1/UQCRC1	39
BP	GO:0009185	ribonucleoside diphosphate metabolic process	38/2619	140/18670	3.308e-05	0.001008	0.000756	NUPR1/NUP160/CBFA2T3/DDIT4/ENTPD4/BAD/NUP153/PGM1/INSR/TPR/PRKAG1/ENO2/NUP50/SLC2A6/NUDT9/SEC13/AK1/RANBP2/PFKFB3/PFKM/IFNG/IGF1/GUK1/NUP210/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/MPP1/TJP2/ALDOC/EIF6/AMPD3/NUP98/ADPGK/NUP62	38
BP	GO:0048010	vascular endothelial growth factor receptor signaling pathway	29/2619	96/18670	3.316e-05	0.001008	0.000756	PRKD2/PGF/PRKCB/FOXC1/SH2D2A/ITGA5/BAIAP2/NCK2/TNMD/CYFIP2/ROCK1/HSPB1/GRB10/SHB/MAPK11/PIK3CB/FGF18/KDR/AXL/VEGFA/MAPKAPK2/ABI1/HIF1A/PAK2/CYFIP1/PTK2B/VEGFB/PIK3CA/NCF1	29
BP	GO:2001169	regulation of ATP biosynthetic process	29/2619	96/18670	3.316e-05	0.001008	0.000756	NUPR1/TREM2/NUP160/CBFA2T3/DDIT4/PID1/NUP153/PINK1/INSR/TPR/PRKAG1/NUP50/SLC2A6/SEC13/RANBP2/PFKFB3/TAZ/IFNG/IGF1/NUP210/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/EIF6/NUP98/NUP62	29
BP	GO:0046632	alpha-beta T cell differentiation	30/2619	101/18670	3.494e-05	0.001057	0.0007929	IRF1/RIPK2/MALT1/RORA/PLA2G2D/SEMA4A/IL4R/TCF7/GPR183/ITK/ADA/RUNX3/CD83/SOCS1/BCL11B/LEF1/PTGER4/RC3H2/ZAP70/PNP/RELB/IFNG/LY9/IL6/PRDM1/SATB1/TNFSF4/HMGB1/BATF/TNFSF8	30
BP	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	48/2619	192/18670	3.521e-05	0.00106	0.0007952	TREM2/JAK2/CCL5/CRLF1/SEMA4D/FBXW7/RIPK2/THBS4/ANGPT1/IL15/PTPRC/HGF/ADAM17/EGF/ITGA5/PRNP/NTRK2/NEDD9/TNFRSF14/NTF3/PECAM1/KIT/EFNA5/ARHGEF2/CTF1/CD40/CD44/CD81/CD3E/IFNG/AGT/IGF1/IL6/HBEGF/EREG/PDGFB/EPHA4/ARL2BP/VEGFA/ABI1/DOCK3/IL6R/PAK2/GHR/ERBB4/PTK2B/BDNF/NCF1	48
BP	GO:0002690	positive regulation of leukocyte chemotaxis	27/2619	87/18670	3.609e-05	0.001081	0.0008111	DYSF/CXCL10/PTN/LGMN/CCL5/MAPK3/CXCL13/PGF/THBS4/ADAM17/SERPINE1/CREB3/PLA2G7/RAC2/IL6/XCL1/VEGFA/HMGB1/CCR7/CXCR2/IL6R/TNFSF14/CCL7/CXCL8/PTK2B/CCR2/VEGFB	27
BP	GO:0001779	natural killer cell differentiation	11/2619	21/18670	3.664e-05	0.001093	0.0008197	RASGRP1/IL15/PTPRC/MERTK/TOX/TUSC2/AXL/PRDM1/PIK3CD/ID2/TYRO3	11
BP	GO:0045089	positive regulation of innate immune response	82/2619	381/18670	3.872e-05	0.001149	0.000862	TNFAIP3/AIM2/NFKBIA/RNF125/IRAK3/LGMN/IRF1/BIRC3/CCL5/RASGRP1/RIPK2/PLCG2/COLEC12/SKP1/TBK1/TRIL/MALT1/HLA-F/HLA-G/MICB/TNIP2/TNIP1/PSMB9/RFTN1/LILRA2/TNIP3/POLR3C/PUM2/BIRC2/HLA-E/TSPAN6/MED1/IRF3/PTPN22/PSMC2/ALPK1/CRTAM/NFKB1/PELI1/RELB/PSMB6/CHUK/HMGB3/S100A1/PSMC3/TLR5/GPATCH3/TXK/IRAK4/EREG/MMP12/MFHAS1/PSMD8/UBB/HMGB1/NOD2/PSMB5/TRAF3/ULBP2/MAPKAPK2/SFPQ/GRAMD4/PSMD10/DDX60/CYLD/IFI16/MUC5AC/NOD1/IKBKG/RAF1/SEC14L1/FCN1/PAK2/TYRO3/BCL10/EP300/MYD88/RIOK3/KRAS/TLR8/ICAM3/NRAS	82
BP	GO:0001959	regulation of cytokine-mediated signaling pathway	45/2619	177/18670	3.927e-05	0.001159	0.0008692	TNFAIP3/SPHK1/IRAK3/TREM2/STAT1/BIRC3/JAK2/CCL5/RIPK2/ADAR/AGPAT1/TBK1/ANGPT1/TRAF1/PTPRC/ADAM17/CARD8/BIRC2/CASP4/SOCS1/SAMHD1/MADD/NOL3/JAK1/MED1/IRF3/PXDN/PPARG/CXCR4/PTPN2/IFNG/CHUK/NR1H2/IL6/VRK2/TXK/AXL/MMP12/HIF1A/CYLD/IL1RN/PADI2/IKBKG/TRIM32/SH2B3	45
BP	GO:0046939	nucleotide phosphorylation	37/2619	136/18670	3.951e-05	0.001159	0.0008692	NUPR1/NME4/NME7/NUP160/CBFA2T3/DDIT4/NME5/NUP153/PGM1/INSR/TPR/PRKAG1/ENO2/NUP50/NME3/SLC2A6/SEC13/AK1/RANBP2/PFKFB3/PFKM/IFNG/IGF1/GUK1/NUP210/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/SUCLG1/ALDOC/EIF6/NUP98/ADPGK/NUP62	37
BP	GO:1902850	microtubule cytoskeleton organization involved in mitosis	36/2619	131/18670	3.959e-05	0.001159	0.0008692	PARP3/TUBG2/NDE1/CHEK2/KIF2A/TPX2/RACGAP1/TPR/NUSAP1/ARHGEF2/DRG1/PRC1/NDC80/DCTN2/EML1/PLK2/CENPE/KIF11/CHMP2A/CCNB1/KIF4A/CLASP1/CDC20/AURKB/DYNC1H1/BIRC5/TACC2/KPNB1/SPAST/SMC1A/SETD2/CHMP1B/TACC3/SPICE1/FLNA/NUP62	36
BP	GO:0007219	Notch signaling pathway	48/2619	193/18670	4.059e-05	0.001182	0.0008869	NFKBIA/NOTCH1/CEBPA/GALNT11/STAT1/SOX9/FBXW7/GOT1/TMEM100/TSPAN15/FOXC1/NLE1/ADAM17/DLGAP5/EGFR/EGF/NOTCH4/CFD/KIT/RFNG/GDPD5/ARRB1/MAML1/POSTN/POFUT1/RBM15/PRKCI/NOS3/GMDS/MYC/PSENEN/DLK1/RBPJ/SORBS2/PLXND1/LLGL2/TIMP4/NOD2/RITA1/JAG2/YBX1/SPEN/APH1B/KAT2B/EP300/APH1A/SEL1L/ZNF423	48
BP	GO:0009152	purine ribonucleotide biosynthetic process	64/2619	280/18670	4.143e-05	0.001202	0.0009012	PDK2/NUPR1/TREM2/NME4/NME7/SNCA/MPC2/NUP160/CBFA2T3/DDIT4/PID1/TECR/IMPDH2/SLC25A1/NME5/NUP153/ADK/PGM1/PINK1/INSR/ACSL5/TPR/PRKAG1/ENO2/NUP50/NME3/SLC2A6/GSTZ1/CYC1/SEC13/AK1/RANBP2/PFKFB3/TAZ/PFKM/IFNG/NPR2/ACAT1/DLD/IGF1/SCD5/ADCY1/PDK1/GUK1/NUP210/COX5B/NCOR1/NUP43/HIF1A/PDHB/NDC1/OGT/PRKAA1/ADCY2/ALDOC/PANK3/EIF6/MPC1/STOML2/AMPD3/NUP98/PAPSS1/ADPGK/NUP62	64
BP	GO:0009142	nucleoside triphosphate biosynthetic process	47/2619	188/18670	4.225e-05	0.001217	0.0009131	NUPR1/TREM2/NME4/NME7/NUP160/CBFA2T3/DDIT4/PID1/IMPDH2/NME5/NUP153/ADK/PGM1/PINK1/INSR/TPR/PRKAG1/ENO2/NUP50/NME3/SLC2A6/CYC1/SEC13/AK1/RANBP2/PFKFB3/TAZ/PFKM/IFNG/IGF1/NUP210/COX5B/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/CTPS1/SUCLG1/TYMS/ALDOC/EIF6/STOML2/NUP98/ADPGK/NUP62	47
BP	GO:0048732	gland development	91/2619	434/18670	4.247e-05	0.001217	0.0009131	PITX1/TNFAIP3/SIX1/SFRP1/PTN/NOTCH1/CEBPA/JARID2/AR/JAK2/SOX9/IGFBP5/FBXW7/MAPK3/QDPR/SMAD3/CFLAR/FOXC1/HGF/SERPINA5/SEMA3A/EZH2/ATM/EGFR/EGF/NOTCH4/TNFRSF11A/ADA/PRMT5/INSR/HFE/BCL11B/HMGCL/RXRA/BMP4/CYP7B1/WNT11/LEF1/CSNK2B/MED1/GPX1/LAMA5/FOXF1/TAF10/ID4/ACAT1/CCNB2/WLS/ASS1/MPST/LRP5/TSPO/INSM1/CDKN1C/BRCA2/PML/RBPJ/CPS1/PCK2/DEAF1/VEGFA/PLXND1/ALDH1A3/ARHGAP35/HOXD9/SOD1/HIF1A/HOXA5/PRDX2/LSR/SIX3/RAF1/FA2H/TYMS/CEBPG/CREB1/ID2/STAT5A/PLXNA1/OAS2/ERBB4/XBP1/KRAS/RPS6KA1/HNRNPD/CEBPB/SMO/SERPINF1/PSAP/ASNS/PIK3CA	91
BP	GO:0032731	positive regulation of interleukin-1 beta production	19/2619	52/18670	4.256e-05	0.001217	0.0009131	AIM2/JAK2/RIPK2/MALT1/SMAD3/LILRA2/NLRP1/CARD8/HSPB1/IFNG/EGR1/TYROBP/HMGB1/NOD2/LPL/IFI16/GSDMD/NOD1/TLR8	19
BP	GO:0007221	positive regulation of transcription of Notch receptor target	10/2619	18/18670	4.309e-05	0.001227	0.0009203	NOTCH1/STAT1/DLGAP5/NOTCH4/MAML1/RBM15/RBPJ/PLXND1/KAT2B/EP300	10
BP	GO:0071214	cellular response to abiotic stimulus	73/2619	331/18670	4.404e-05	0.001243	0.0009321	AKR1B1/SFRP1/DYSF/PTN/IRF1/SOX9/ECT2/GPR88/MAPK3/MFAP4/ERCC1/NIPBL/FAS/GOT1/ATR/CRADD/CHEK2/METAP1/CHEK1/ATM/BAD/SLC38A2/EGFR/SERPINB6/WNT11/ARHGEF2/USP47/KCNJ2/CD40/PTGER4/GUCA1A/CRYAB/NFKB1/RELB/AGT/TSPO/MYC/EGR1/TLR5/NAMPT/AURKB/CASP9/CASP8AP2/PKD2L1/RS1/DDB2/RAD1/MICU1/RUVBL2/PTPRK/NET1/WRN/AQP2/MCOLN1/IFI16/TNFSF14/ADIRF/RAB11B/RAD9A/METAP2/BCL10/CDKN1A/N4BP1/EP300/MYD88/TSPYL5/CRY1/TLR8/ATF4/LETM1/HSPA5/HMGA2/RBL2	73
BP	GO:0104004	cellular response to environmental stimulus	73/2619	331/18670	4.404e-05	0.001243	0.0009321	AKR1B1/SFRP1/DYSF/PTN/IRF1/SOX9/ECT2/GPR88/MAPK3/MFAP4/ERCC1/NIPBL/FAS/GOT1/ATR/CRADD/CHEK2/METAP1/CHEK1/ATM/BAD/SLC38A2/EGFR/SERPINB6/WNT11/ARHGEF2/USP47/KCNJ2/CD40/PTGER4/GUCA1A/CRYAB/NFKB1/RELB/AGT/TSPO/MYC/EGR1/TLR5/NAMPT/AURKB/CASP9/CASP8AP2/PKD2L1/RS1/DDB2/RAD1/MICU1/RUVBL2/PTPRK/NET1/WRN/AQP2/MCOLN1/IFI16/TNFSF14/ADIRF/RAB11B/RAD9A/METAP2/BCL10/CDKN1A/N4BP1/EP300/MYD88/TSPYL5/CRY1/TLR8/ATF4/LETM1/HSPA5/HMGA2/RBL2	73
BP	GO:0048524	positive regulation of viral process	31/2619	107/18670	4.447e-05	0.001249	0.0009369	NOTCH1/SRPK1/CCL5/CHD1/ADAR/POLR2J/POLR2I/POLR2L/POLR2E/POLR2F/KPNA2/APOE/RRP1B/LEF1/PC/CD28/POLR2C/TRIM21/CTDP1/CHMP2A/POLR2G/YTHDC2/TOP2A/PPIE/PPIB/EP300/CDK9/NR5A2/VAPA/STAU1/PPIH	31
BP	GO:0051052	regulation of DNA metabolic process	90/2619	429/18670	4.572e-05	0.001275	0.000956	EYA2/CDC7/PARP3/SMCHD1/PRKD2/TFRC/IL27RA/FBXW7/MAPK3/ERCC1/HNRNPA2B1/NBN/CCNA2/IL7R/ATR/DNMT1/PTPRC/CHEK2/TNKS2/HGF/CHEK1/TRIP12/ATM/ATF7IP/DNA2/EGFR/KPNA2/ZNF365/THOC1/PRMT5/RLF/DDX11/DBF4/MMS19/PPARG/DONSON/CD28/GZMA/CD40/DEK/GPER1/SETMAR/FOXM1/APAF1/DCP2/MYC/HCRT/IL6/BRCA2/PML/EREG/ZNF93/ATRX/PDGFB/HMBOX1/AURKB/HNRNPA1/PARP4/TNFSF4/HMGB1/UBQLN4/PRKCQ/RAD50/NABP2/WRN/USP9X/SMC1A/ERCC2/TIMELESS/SETD2/BABAM1/CEBPG/CDK1/KPNA1/ID3/PARM1/CDKN1A/UBR5/PTK2B/CDK9/HNRNPD/STOML2/RFC2/ACTR2/ZNF91/HMGA2/WDR70/TWIST1/PIK3CA/FBXO5	90
BP	GO:0002262	myeloid cell homeostasis	39/2619	147/18670	4.578e-05	0.001275	0.000956	P4HTM/STAT1/JAK2/ADAR/SLC7A11/ADAM17/MERTK/IREB2/KIT/BMP4/EPB42/HOXB6/MED1/JMJD6/PTPN2/PTBP3/PIK3CB/IL6/AXL/MFHAS1/DNASE2/ZNF16/VEGFA/HMGB1/CXCR2/ARID4A/NFE2L1/SOD1/HIF1A/HOXA5/ERCC2/PIK3CD/CEBPG/ID2/SFXN1/SH2B3/CCR2/AMPD3/TRIM58	39
BP	GO:0050707	regulation of cytokine secretion	51/2619	210/18670	4.669e-05	0.001294	0.0009708	TNFAIP3/GBP1/AIM2/CD200/TNFRSF1B/BTN2A2/RASGRP1/IL27RA/MAPK3/RIPK2/ANGPT1/SYT11/IL4R/LILRA2/TNFRSF21/NLRP1/CARD8/TNFRSF14/SOCS1/HTR2B/IRF3/PTPN22/CRTAM/FGR/PTGER4/F2R/POSTN/IFNG/MAPK11/CHUK/GHSR/TLR5/PML/MMP12/IL17RB/HMGB1/GLMN/CCR7/NOD2/FERMT1/CD58/LPL/IL17RC/CD2/GSDMD/FCN1/XBP1/TLR8/IL17RA/TWIST1/SRGN	51
BP	GO:1903578	regulation of ATP metabolic process	34/2619	122/18670	4.699e-05	0.001297	0.0009728	NUPR1/TREM2/COX7A1/SNCA/NUP160/CBFA2T3/DDIT4/PID1/NUP153/PINK1/INSR/TPR/PRKAG1/NUP50/SLC2A6/SEC13/RANBP2/PFKFB3/TAZ/IFNG/TSPO/IGF1/CCNB1/NUP210/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/CDK1/EIF6/NUP98/NUP62	34
BP	GO:0006110	regulation of glycolytic process	25/2619	79/18670	4.827e-05	0.001326	0.0009949	NUPR1/NUP160/CBFA2T3/DDIT4/NUP153/INSR/TPR/PRKAG1/NUP50/SLC2A6/SEC13/RANBP2/PFKFB3/IFNG/IGF1/NUP210/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/EIF6/NUP98/NUP62	25
BP	GO:0000819	sister chromatid segregation	47/2619	189/18670	4.87e-05	0.001332	0.0009993	FBXW7/TUBG2/NIPBL/ATM/DLGAP5/PTTG1/RACGAP1/TPR/DDX11/BUB1B/NUSAP1/SPAG5/LCMT1/SMC5/NCAPH/CDCA8/CHMP6/KIF18B/PRC1/NDC80/CENPE/CHMP2A/NAA50/CCNB1/NCAPG/MIS12/KIF4A/CDC20/ATRX/AURKB/RAD51C/TOP2A/MCMBP/SFPQ/KPNB1/SMC4/KATNB1/AKAP8/SMC1A/CHMP1B/TACC3/CENPC/PTTG2/CENPF/NUP62/POGZ/FBXO5	47
BP	GO:0007568	aging	71/2619	321/18670	5.048e-05	0.001375	0.001031	SMC6/TNFRSF1B/IGFBP5/IGFBP2/MAPK3/ERCC1/SNCA/IL15/HLA-G/ATR/BCL2A1/CHEK2/CHEK1/PTH1R/ATM/PRNP/TIMP2/NQO1/SERPINE1/ADA/IDE/ING2/PENK/SMC5/CRYAB/TPRA1/CAT/GPX4/NTRK1/FOXM1/KRT14/PLK2/APAF1/POLG/SIRT3/AGT/ASS1/DLD/TSPO/COMP/CDKN1C/BRCA2/PML/NAMPT/AURKB/CASP9/PLA2R1/PPP3CA/MAP3K3/KAT6A/SOD1/WRN/SRR/ERCC2/TYMS/CREB1/CDK1/ID2/TIMP1/CDKN1A/NDUFS6/KRAS/COL4A2/SERPINF1/HMGA1/HMGA2/ATP2B1/TH/TWIST1/NUP62/FBXO5	71
BP	GO:0051098	regulation of binding	80/2619	373/18670	5.419e-05	0.00147	0.001102	NFKBIA/JAK2/FBXW7/MAPK3/RIPK2/ANGPT1/SRI/NIPBL/SMAD3/SLPI/PCBD1/LRPAP1/BTAF1/PTPRF/FOXC1/PEX19/EGF/SMARCD3/TDG/CTNNBIP1/APOE/GSK3B/MDFI/HFE/BMP4/DDX11/MAPRE3/SPON1/LEF1/RFNG/CSNK2B/PIM2/PPARG/ROCK1/GZMA/NMD3/ARRB1/ADRB2/TAF10/ID4/IFNG/PLK2/ARHGEF7/IGF1/LDOC1/PDGFB/EPHA4/HMBOX1/CSNK1A1/AURKB/PLXND1/PIN1/HMGB1/HJURP/CSNK1E/RUVBL2/PPP3CA/PEX14/CAMK1/ERCC2/CYLD/IFI16/CEBPG/ID2/ID3/TCF7L2/HIP1R/LARP6/LGALS3/EP300/CAPRIN2/MARK3/CDK9/SMO/HSPA5/HMGA2/BDNF/MEPCE/DDIT3/TWIST1	80
BP	GO:0044706	multi-multicellular organism process	53/2619	222/18670	5.479e-05	0.001474	0.001105	AKR1B1/PTN/AR/EPYC/MAGED2/IGFBP5/IGFBP2/MAPK3/PGF/CD38/HSD11B2/SLC38A2/DDO/ITGA5/IDO1/COMT/BSG/STC1/ANGPT2/HFE/RXRA/STS/MED1/HPGD/KLK14/PTGFR/POLR1B/ARID1A/PLA2G4C/CLIC5/MAFF/AGT/CRHBP/LDOC1/PAPPA/APOL2/GHSR/NAMPT/PRDM1/LNPEP/PNOC/TMED2/SOD1/AGRP/EMP2/TAC1/DAZAP1/TIMP1/FBLN1/KRAS/STC2/CORIN/EPOR	53
BP	GO:1901605	alpha-amino acid metabolic process	53/2619	222/18670	5.479e-05	0.001474	0.001105	CBS/FAH/P4HTM/HPD/IVD/ALDH7A1/BHMT2/HAAO/SDS/QDPR/THNSL2/GAMT/PEMT/DDAH1/GOT1/PCBD1/SLC7A11/DDO/IDO1/COMT/AGMAT/SMS/HMGCL/GCAT/ASRGL1/GSTZ1/CRTAP/SERINC5/MSRA/DDAH2/GATM/ACAT1/HDC/ASS1/MPST/DLD/NOS3/PSPH/CPS1/AHCY/OAT/EGLN3/DCT/SRR/ATP2B4/CTPS1/SEPHS1/HNMT/PYCR1/ALDH6A1/ALDH18A1/ASNS/TH	53
BP	GO:0060249	anatomical structure homeostasis	91/2619	437/18670	5.547e-05	0.001475	0.001106	FGGY/TNFAIP3/AKR1B1/NOTCH1/SMC6/PARP3/TNFRSF11B/SOX9/DCLRE1C/HAAO/TFRC/MAPK3/ERCC1/HNRNPA2B1/NBN/POLD2/SERPINA3/ATR/CD38/FOXC1/TNKS2/MDM1/PTH1R/ATM/RBP4/BARD1/DNA2/EGFR/LTBP3/ZNF365/TNFRSF11A/NHP2/RPA1/RCN3/RPA3/POLD4/BBS1/SMC5/BBS4/TCIRG1/S1PR1/F2R/HSPB1/ADRB2/PFKM/DCP2/ATP2B2/NOS3/RAC2/MYC/TAOK1/IL6/BRCA2/PML/ATRX/HMBOX1/AURKB/VEGFA/HNRNPA1/CA2/P2RX4/RAD51C/LIPA/PRKCQ/NOD2/RAD50/IQCB1/NABP2/CACNB2/SOD1/WRN/SNX10/HIF1A/GAA/CALB2/PRKAA1/CACNA1D/KRT1/TYRO3/CXADR/NCDN/TRIM32/CST4/KRAS/PTK2B/HNRNPD/CCR2/SMO/FH/RFC2/ATP2B1	91
BP	GO:0009135	purine nucleoside diphosphate metabolic process	37/2619	138/18670	5.556e-05	0.001475	0.001106	NUPR1/NUP160/CBFA2T3/DDIT4/BAD/NUP153/PGM1/INSR/TPR/PRKAG1/ENO2/NUP50/SLC2A6/NUDT9/SEC13/AK1/RANBP2/PFKFB3/PFKM/IFNG/IGF1/GUK1/NUP210/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/MPP1/TJP2/ALDOC/EIF6/AMPD3/NUP98/ADPGK/NUP62	37
BP	GO:0009179	purine ribonucleoside diphosphate metabolic process	37/2619	138/18670	5.556e-05	0.001475	0.001106	NUPR1/NUP160/CBFA2T3/DDIT4/BAD/NUP153/PGM1/INSR/TPR/PRKAG1/ENO2/NUP50/SLC2A6/NUDT9/SEC13/AK1/RANBP2/PFKFB3/PFKM/IFNG/IGF1/GUK1/NUP210/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/MPP1/TJP2/ALDOC/EIF6/AMPD3/NUP98/ADPGK/NUP62	37
BP	GO:0040014	regulation of multicellular organism growth	22/2619	66/18670	5.602e-05	0.001481	0.001111	DIO3/LGMN/GAMT/NIPBL/TNKS2/FTO/CDK4/GDF5/BBS4/ADRB2/IGF1/GHSR/NPY1R/SOD1/PPIB/CREB1/STAT5A/GHR/SGPL1/SMO/STC2/PIK3CA	22
BP	GO:0022409	positive regulation of cell-cell adhesion	59/2619	255/18670	5.633e-05	0.001483	0.001112	CCL5/ADAM19/BTN2A2/RASGRP1/TFRC/IGFBP2/RIPK2/CXCL13/MALT1/IL15/HLA-G/IL7R/IL4R/LILRB2/PTPRC/BAD/HSPH1/CTLA4/NCK2/ADA/RUNX3/TNFRSF14/CD83/HLA-E/SOCS1/CD28/ANK3/IL1RL2/CD44/ZAP70/ELANE/MAP3K8/PNP/CD81/CD3E/CD27/IFNG/LCK/IGF1/EFNB1/IL6/XCL1/TNFSF4/HMGB1/CCR7/PRKCQ/NOD2/HAS2/CYLD/IL6R/TNFSF14/VNN1/PAK2/BCL10/XBP1/CCR2/CD40LG/PODXL/PIK3CA	59
BP	GO:1901653	cellular response to peptide	82/2619	385/18670	5.675e-05	0.001488	0.001116	PTPRE/AKR1B1/PDK2/TREM2/LGMN/STAT1/JAK2/ENPP1/FIS1/RIPK2/SH2B2/PRKAR2A/ATP6V0D1/GOT1/CCNA2/PRKCB/CFLAR/SOS1/PID1/PRNP/BAIAP2/GSK3B/INSR/CDK4/CASP4/SOCS1/CYP11A1/IDE/DDX11/OSBPL8/ARHGEF2/PTPN22/PPARG/ROCK1/GPER1/PTPN2/TCIRG1/ADRB2/NFKB1/GRB10/MZB1/PHIP/WDTC1/AGT/ASS1/CRHBP/PRKCI/IGF1/RAB13/LDOC1/GHSR/ADCY1/CPS1/NAMPT/PCK2/EPHA4/CA2/ATP6V0E2/PRKCQ/NOD2/VAMP2/LPL/OGT/TIMELESS/PRKAA1/BCL2L2/NOD1/NGFR/ADCY2/CREB1/STAT5A/GHR/KAT2B/CYFIP1/XBP1/INHBB/RAP1B/LPIN1/CISH/ATP2B1/PIK3CA/SORBS1	82
BP	GO:0044242	cellular lipid catabolic process	52/2619	217/18670	5.774e-05	0.001508	0.001131	FUCA1/PNPLA4/SPHK1/AKR1B10/PNPLA6/IVD/LIPC/PLCG2/ECI2/ECHS1/ETFB/ABHD6/ACOX2/PLA2G15/DECR2/MECR/BDH2/APOE/PHYH/PCCB/PRDX6/ECH1/ASAH1/PEX7/GDE1/HADH/PLA2G4C/PEX2/APOC1/ECI1/ACAT1/SCP2/AKR1C3/GM2A/CPS1/PCK2/ALDH3A2/NEU1/ACADM/LPL/ACOX1/ACAA2/ACOT8/MCAT/CRAT/FABP7/SGPL1/FABP3/ABHD2/LPIN1/PSAP/TWIST1	52
BP	GO:1902275	regulation of chromatin organization	46/2619	185/18670	5.843e-05	0.00152	0.00114	MTF2/JARID2/KDM5A/PRKD2/MAPK3/SNCA/NIPBL/WDR61/DNMT1/CHEK1/TRIP12/ATM/ATF7IP/NAP1L2/TADA3/PINK1/MKI67/ATAD2B/SART3/SET/TPR/ING2/SETD5/ZNHIT1/ZNF451/EID1/KDM3A/ARRB1/AUTS2/CCNB1/TAF7/ATRX/VEGFA/EED/PAXBP1/RUVBL2/AKAP8/OGT/PADI2/ATAD2/PIWIL2/UBR5/CDK9/HMGA1/WDR70/TWIST1	46
BP	GO:0046390	ribose phosphate biosynthetic process	67/2619	300/18670	5.943e-05	0.001539	0.001154	PDK2/NUPR1/TREM2/NME4/NME7/SNCA/MPC2/NUP160/CBFA2T3/DDIT4/PID1/TECR/IMPDH2/SLC25A1/NME5/NUP153/ADK/PGM1/PINK1/INSR/ACSL5/TPR/PRKAG1/ENO2/NUP50/NME3/SLC2A6/GSTZ1/CYC1/SEC13/AK1/RANBP2/PFKFB3/TAZ/PFKM/IFNG/NPR2/ACAT1/DLD/IGF1/SCD5/ADCY1/PDK1/GUK1/NUP210/COX5B/NCOR1/NUP43/HIF1A/PDHB/NDC1/OGT/PRKAA1/CTPS1/ADCY2/ALDOC/PANK3/EIF6/PRPS1/MPC1/PRPS2/STOML2/AMPD3/NUP98/PAPSS1/ADPGK/NUP62	67
BP	GO:0046635	positive regulation of alpha-beta T cell activation	21/2619	62/18670	6.295e-05	0.001624	0.001218	RIPK2/MALT1/IL4R/PTPRC/HSPH1/ADA/RUNX3/CD83/HLA-E/SOCS1/CD28/ZAP70/PNP/CD81/CD3E/IFNG/XCL1/TNFSF4/PRKCQ/IL6R/CCR2	21
BP	GO:0019883	antigen processing and presentation of endogenous antigen	11/2619	22/18670	6.4e-05	0.001644	0.001233	TAP1/HLA-C/HLA-F/HLA-G/HLA-A/HLA-B/HLA-E/HFE/IDE/TAPBP/TAP2	11
BP	GO:0006370	7-methylguanosine mRNA capping	14/2619	33/18670	6.509e-05	0.001658	0.001244	POLR2J/POLR2I/POLR2L/POLR2E/POLR2F/CMTR1/RNGTT/POLR2C/CCNH/POLR2G/ERCC2/NCBP2/MNAT1/GTF2H3	14
BP	GO:0046633	alpha-beta T cell proliferation	14/2619	33/18670	6.509e-05	0.001658	0.001244	IRF1/RIPK2/ELF4/IL15/PTPRC/TNFRSF14/HLA-E/CD28/ZAP70/CD81/CD3E/XCL1/TNFSF4/CCR2	14
BP	GO:0006165	nucleoside diphosphate phosphorylation	36/2619	134/18670	6.647e-05	0.001687	0.001265	NUPR1/NME4/NME7/NUP160/CBFA2T3/DDIT4/NME5/NUP153/PGM1/INSR/TPR/PRKAG1/ENO2/NUP50/NME3/SLC2A6/SEC13/AK1/RANBP2/PFKFB3/PFKM/IFNG/IGF1/NUP210/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/SUCLG1/ALDOC/EIF6/NUP98/ADPGK/NUP62	36
BP	GO:1903532	positive regulation of secretion by cell	84/2619	399/18670	7.105e-05	0.00179	0.001342	AIM2/TREM2/JAK2/RPH3AL/RASGRP1/MAPK3/RIPK2/TACR2/SEC24A/SNCA/SRI/HLA-F/RAB27A/IL4R/MPC2/CD38/SDC1/LILRA2/RBP4/BAD/EGFR/NLRP1/PINK1/CARD8/TNFRSF14/HLA-E/HFE/HTR2B/IRF3/PTPN22/CRTAM/FGR/PTGER4/GPER1/ARRB1/F2R/POSTN/OXCT1/IFNG/SIRT3/WLS/AGT/MAPK11/CHUK/IGF1/CHMP2A/VAMP7/ANG/IL6/CLASP1/MMP12/IL17RB/TNFSF4/HMGB1/GLMN/NOD2/ANO1/FERMT1/CACNB2/CD58/LPL/HIF1A/TMF1/NMB/IL17RC/TARDBP/CD2/TAC1/GSDMD/CACNA1D/CREB1/GAL/FCN1/TCF7L2/SYT1/GOLPH3/XBP1/INHBB/RAB15/TLR8/EXOC1/MYH10/IL17RA/TWIST1	84
BP	GO:0051235	maintenance of location	72/2619	330/18670	7.11e-05	0.00179	0.001342	CXCL9/NFKBIA/DYSF/CXCL10/GPAA1/ENPP1/SLC18A2/FBXW7/PLCG2/VPS13C/SKP1/SNCA/SRI/CLMN/ASPM/CXCL11/KDELR3/PTPRC/ARL2/FTO/SYNE2/BARD1/UVRAG/PINK1/APOE/MEST/MDFI/CCR5/NOL3/HTR2B/OSBPL8/PPARG/ANK3/BBS4/GPER1/PTPN2/F2R/NFKB1/LCK/ITPR2/FTL/MCOLN3/TSPO/NBL1/NR1H2/IL6/PML/GM2A/XCL1/CD19/ARL2BP/SCIN/PLCE1/CCR7/TMSB10/LPL/PSMD10/GAA/LIME1/TPCN1/AKAP9/MCOLN1/TLN2/PLIN2/GOLPH3/CRY1/FLNA/PTK2B/LETM1/HSPA5/DDIT3/SRGN	72
BP	GO:0007565	female pregnancy	47/2619	192/18670	7.382e-05	0.001851	0.001388	AKR1B1/PTN/AR/EPYC/MAGED2/IGFBP5/IGFBP2/MAPK3/PGF/CD38/HSD11B2/SLC38A2/ITGA5/IDO1/COMT/BSG/STC1/ANGPT2/HFE/RXRA/STS/MED1/HPGD/POLR1B/ARID1A/CLIC5/AGT/CRHBP/LDOC1/PAPPA/APOL2/GHSR/NAMPT/PRDM1/LNPEP/PNOC/TMED2/SOD1/AGRP/EMP2/DAZAP1/TIMP1/FBLN1/KRAS/STC2/CORIN/EPOR	47
BP	GO:0043901	negative regulation of multi-organism process	43/2619	171/18670	7.586e-05	0.001895	0.001421	HPGDS/TNFAIP3/RNF125/SRPK1/STAT1/CCL5/FAM111A/SLPI/MICB/TNIP1/LILRA2/CARD8/ADA/APOBEC3C/TRIM26/HTRA1/TSPAN6/ZC3HAV1/ISG20/FAM3A/CCL8/NPR2/BANF1/TRIB1/TRIM21/IGF1/GPATCH3/PML/PPM1B/IFITM2/MBL2/CCNK/PRDX2/HDAC1/IFI16/TARDBP/SEC14L1/FCN1/TIMP1/TRIM32/RIOK3/VAPA/HMGA2	43
BP	GO:0030811	regulation of nucleotide catabolic process	25/2619	81/18670	7.654e-05	0.001904	0.001428	NUPR1/NUP160/CBFA2T3/DDIT4/NUP153/INSR/TPR/PRKAG1/NUP50/SLC2A6/SEC13/RANBP2/PFKFB3/IFNG/IGF1/NUP210/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/EIF6/NUP98/NUP62	25
BP	GO:0043491	protein kinase B signaling	61/2619	269/18670	7.884e-05	0.00194	0.001455	SETX/SOX9/CCL5/BTN2A2/IGFBP5/ANGPT1/HLA-G/TMEM100/BTC/HGF/EGFR/EGF/MERTK/PINK1/CX3CR1/NTRK2/INSR/KIT/FGF20/ERBB2/OSBPL8/MAGI2/RCN3/PIK3C2B/CD28/PLEKHA1/GPX1/CD40/GPER1/LCK/TRAT1/PIK3CB/IGF1/FGF18/KDR/RAC2/PIK3R5/HBEGF/AKR1C3/MYOC/AXL/EREG/PDGFB/CD19/MFHAS1/MTDH/P2RX4/CALCR/CCR7/CIB1/PIK3CD/TCF7L2/TYRO3/ERBB4/TSPYL5/SH2B3/PHLPP1/FGF5/ARFGEF1/DDIT3/PIK3CA	61
BP	GO:0043010	camera-type eye development	69/2619	314/18670	7.907e-05	0.00194	0.001455	MAB21L2/EFEMP1/CRYBB1/PTN/DIO3/WNT5B/SOX9/LAMC3/TMEM231/SMAD3/LIMK2/TMOD1/SLC7A11/FOXC1/SOS1/MDM1/RBP4/IMPDH2/EGFR/CRYBG3/SMARCD3/MERTK/NTRK2/CDK4/MYOM2/BCL11B/RXRA/BMP4/FAT1/MED1/B9D1/FKBP8/GPM6A/JMJD6/CRYAB/TCIRG1/ROM1/OSR2/ARID1A/LRP5/CDKN1C/VEGFA/TGIF2/IFT140/ALDH1A3/ARHGAP35/TSKU/TENM3/RS1/IRX5/NINJ1/PRPH2/PFDN5/PHACTR4/HIF1A/HDAC1/NF2/ATP2B4/SIX3/MAF/COL4A1/RING1/DSCAM/SERPINF1/KERA/MYH10/ATP2B1/TH/TWIST1	69
BP	GO:0006664	glycolipid metabolic process	31/2619	110/18670	7.917e-05	0.00194	0.001455	FUCA1/PIGT/GPAA1/GAL3ST4/PIGK/PGAP2/CTSA/PIGA/KIT/PIGP/B3GALNT1/DPM3/STS/ASAH1/UGCG/CLN6/HEXA/ST3GAL2/GM2A/PIGH/NEU1/PRKAA1/PIGZ/FA2H/SCCPDH/PIGC/ST8SIA2/PGAP3/PSAP/CERK/B4GALT3	31
BP	GO:0031589	cell-substrate adhesion	76/2619	354/18670	7.948e-05	0.00194	0.001455	GBP1/SFRP1/PTN/NOTCH1/NDNF/JAK2/AKIP1/LAMC3/FBLN5/ANGPT1/TRIP6/MACF1/SMAD3/MICALL2/SPOCK1/ARL2/ITGBL1/ITGAL/ITGA5/MERTK/SERPINE1/ANGPT2/NEDD9/PRKX/GSK3B/CORO2B/LIMCH1/PECAM1/EFNA5/CD96/ROCK1/ITGB7/LAMA5/CD44/TMEM8B/FERMT2/FOXF1/POSTN/CD3E/VAMP3/ARHGEF7/CD63/PIK3CB/KDR/RAC2/MAP4K4/CLASP1/MYOC/AXL/MMP12/VEGFA/CCR7/AP1AR/FERMT1/SEMA3E/NINJ1/COL5A3/PTPRK/EMID1/SPOCK2/EMP2/HAS2/NF2/PARVB/CTTN/CIB1/ITGB5/TYRO3/FBLN1/COL3A1/ACTN1/FLNA/PTK2B/HOXA7/FZD7/SORBS1	76
BP	GO:0046641	positive regulation of alpha-beta T cell proliferation	10/2619	19/18670	7.952e-05	0.00194	0.001455	RIPK2/PTPRC/HLA-E/CD28/ZAP70/CD81/CD3E/XCL1/TNFSF4/CCR2	10
BP	GO:0019884	antigen processing and presentation of exogenous antigen	45/2619	182/18670	8.07e-05	0.001961	0.001471	TAP1/HLA-C/LGMN/HLA-DRB4/SEC24A/HLA-F/HLA-G/HLA-A/PSMB9/KIF2A/AP1B1/RACGAP1/DCTN6/DCTN3/CTSF/AP2M1/HLA-B/HLA-E/CAPZA1/SEC22B/PSMC2/SEC13/TAPBP/DCTN2/VAMP3/PSMB6/CENPE/KIF11/CHUK/PSMC3/DYNC1I1/KIF4A/KIF15/HLA-DOB/AP1S1/HLA-DQB1/DYNC1H1/LNPEP/PSMD8/TAP2/PSMB5/PSMD10/IKBKG/ITGB5/NCF1	45
BP	GO:0045787	positive regulation of cell cycle	82/2619	389/18670	8.226e-05	0.001991	0.001493	CDC25B/SPHK1/LGMN/CDC7/ECT2/NIPBL/CRADD/BTC/CHEK2/CHEK1/EZH2/ADAM17/ATM/DLGAP5/EGFR/EGF/SMARCD3/CKS1B/RACGAP1/THOC1/INSR/CDK4/TPR/DDX11/DBF4/MAPRE3/NUSAP1/SPAG5/GDPD5/MED1/CD28/SMC5/CDC14A/POLDIP2/GPER1/SETMAR/CKS2/NDC80/PHIP/CCNT2/PLK2/TRIM21/LRP5/IGF1/INSM1/CCNB1/CRLF3/BRCA2/PML/EREG/ATRX/PDGFB/AURKB/ZNF16/DYNC1H1/RAD51C/YTHDC2/DTL/SFPQ/SSTR5/SPAST/PSMD10/CCNK/GTSE1/CDK1/ID2/CCND2/CDKN1A/MNAT1/EP300/TRIM32/HSPA2/PIWIL2/CDK9/HMGA2/ASNS/RAD51B/MEPCE/RBL2/NUP62/DAZL/FBXO5	82
BP	GO:0051701	interaction with host	50/2619	209/18670	8.295e-05	0.002	0.0015	TFRC/SLAMF1/SMAD3/TNIP1/THOC2/BAD/NUP153/EGFR/SIVA1/ITGA5/KPNA2/UVRAG/THOC1/INSR/TNFRSF14/TRIM26/RRAGA/IDE/CCR5/RXRA/EXOC7/PC/ITGB7/CXCR4/CD81/CCL8/TUSC2/CR1/TRIM21/CHMP2A/EXOC2/PML/AXL/KPNB1/IFITM2/CCNK/TYMS/ITGB5/CDK1/KPNA1/FCN1/TYRO3/SLC20A2/CXADR/TRIM32/KPNA3/CXCL8/ANPEP/NPC1/VAPA	50
BP	GO:0009145	purine nucleoside triphosphate biosynthetic process	43/2619	172/18670	8.763e-05	0.002105	0.001579	NUPR1/TREM2/NME4/NME7/NUP160/CBFA2T3/DDIT4/PID1/IMPDH2/NME5/NUP153/ADK/PGM1/PINK1/INSR/TPR/PRKAG1/ENO2/NUP50/NME3/SLC2A6/CYC1/SEC13/RANBP2/PFKFB3/TAZ/PFKM/IFNG/IGF1/NUP210/COX5B/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/ALDOC/EIF6/STOML2/NUP98/ADPGK/NUP62	43
BP	GO:0032481	positive regulation of type I interferon production	24/2619	77/18670	8.89e-05	0.002127	0.001596	STAT1/IRF1/RIPK2/PLCG2/TBK1/LRRFIP1/POLR2L/POLR3C/POLR2E/POLR2F/IRF3/PTPN22/NFKB1/CHUK/MMP12/HMGB1/SETD2/IFI16/DDX41/EP300/MYD88/POLR1C/RIOK3/TLR8	24
BP	GO:0007050	cell cycle arrest	55/2619	237/18670	9.077e-05	0.002164	0.001623	BRINP1/NOTCH1/IRF1/GAS1/BRINP3/NBN/MLF1/SMAD3/CRADD/CHEK2/ATM/CDKN2C/BARD1/PRR11/PRNP/CDK4/RRAGA/BIN1/PRKAG1/PRKAB1/MAGI2/CDC14A/GPER1/SETMAR/FOXM1/IFNG/PLK2/CGRRF1/INSM1/CCNB1/MYC/CRLF3/CDKN1C/PML/DHCR24/LAMTOR2/MLST8/CCNK/PRKAA1/BRINP2/GTSE1/CDK1/ID2/CGREF1/RRAGD/TCF7L2/KAT2B/CDKN1A/EP300/CXCL8/CDK9/HMGA2/CAB39L/DDIT3/RBL2	55
BP	GO:0032611	interleukin-1 beta production	29/2619	101/18670	9.224e-05	0.00219	0.001643	TNFAIP3/AIM2/SPHK1/TREM2/JAK2/RIPK2/MALT1/SMAD3/LILRA2/NLRP1/CX3CR1/CARD8/CMA1/F2R/HSPB1/IFNG/IGF1/GHSR/EGR1/PML/TYROBP/HMGB1/CCR7/NOD2/LPL/IFI16/GSDMD/NOD1/TLR8	29
BP	GO:0009260	ribonucleotide biosynthetic process	65/2619	293/18670	9.362e-05	0.002213	0.00166	PDK2/NUPR1/TREM2/NME4/NME7/SNCA/MPC2/NUP160/CBFA2T3/DDIT4/PID1/TECR/IMPDH2/SLC25A1/NME5/NUP153/ADK/PGM1/PINK1/INSR/ACSL5/TPR/PRKAG1/ENO2/NUP50/NME3/SLC2A6/GSTZ1/CYC1/SEC13/AK1/RANBP2/PFKFB3/TAZ/PFKM/IFNG/NPR2/ACAT1/DLD/IGF1/SCD5/ADCY1/PDK1/GUK1/NUP210/COX5B/NCOR1/NUP43/HIF1A/PDHB/NDC1/OGT/PRKAA1/CTPS1/ADCY2/ALDOC/PANK3/EIF6/MPC1/STOML2/AMPD3/NUP98/PAPSS1/ADPGK/NUP62	65
BP	GO:0042113	B cell activation	68/2619	310/18670	9.39e-05	0.002213	0.00166	SLAMF8/TNFAIP3/SFRP1/PARP3/CD320/DCLRE1C/TFRC/IL27RA/PLCG2/ERCC1/NBN/MALT1/PRKCB/TNIP2/IL7R/PTPRC/CD38/GPR183/ADAM17/ATM/BAD/TNFRSF21/CTLA4/DOCK10/TPD52/ADA/THOC1/GON4L/KIT/LAX1/AKAP17A/IGHM/LEF1/CD28/CD40/PTPN2/KLF6/TCIRG1/ZAP70/CD81/PELI1/NTRK1/MZB1/TRBC1/CD27/HMGB3/IL6/RBPJ/TYROBP/CD19/TNFSF4/NOD2/BATF/IGLL5/ZFP36L2/IGLC1/CYLD/CTPS1/PIK3CD/TCF3/CEBPG/ID2/CDKN1A/EP300/XBP1/MS4A1/PTK2B/CD40LG	68
BP	GO:0043523	regulation of neuron apoptotic process	50/2619	210/18670	9.428e-05	0.002214	0.00166	SIX1/NUPR1/LGMN/NDNF/JAK2/CRLF1/FIS1/FBXW7/ANGPT1/SNCA/SIGMAR1/TOX3/ATM/MAP3K11/PRNP/PINK1/CX3CR1/NQO1/NTRK2/APOE/NTF3/SET/GDF5/FGF20/ROCK1/ARRB1/F2R/NTRK1/PRKCI/UBE2M/EN1/AXL/TYROBP/CASP9/PIN1/EGLN3/NAIP/MCL1/SOD1/HIF1A/TYRO3/ATF2/KRAS/PTK2B/CEBPB/ATF4/TRIM2/BDNF/DDIT3/PIK3CA	50
BP	GO:0046031	ADP metabolic process	34/2619	126/18670	9.512e-05	0.002221	0.001666	NUPR1/NUP160/CBFA2T3/DDIT4/BAD/NUP153/PGM1/INSR/TPR/PRKAG1/ENO2/NUP50/SLC2A6/NUDT9/SEC13/AK1/RANBP2/PFKFB3/PFKM/IFNG/IGF1/NUP210/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/ALDOC/EIF6/AMPD3/NUP98/ADPGK/NUP62	34
BP	GO:1903509	liposaccharide metabolic process	31/2619	111/18670	9.528e-05	0.002221	0.001666	FUCA1/PIGT/GPAA1/GAL3ST4/PIGK/PGAP2/CTSA/PIGA/KIT/PIGP/B3GALNT1/DPM3/STS/ASAH1/UGCG/CLN6/HEXA/ST3GAL2/GM2A/PIGH/NEU1/PRKAA1/PIGZ/FA2H/SCCPDH/PIGC/ST8SIA2/PGAP3/PSAP/CERK/B4GALT3	31
BP	GO:0009452	7-methylguanosine RNA capping	14/2619	34/18670	9.643e-05	0.002223	0.001667	POLR2J/POLR2I/POLR2L/POLR2E/POLR2F/CMTR1/RNGTT/POLR2C/CCNH/POLR2G/ERCC2/NCBP2/MNAT1/GTF2H3	14
BP	GO:0034205	amyloid-beta formation	14/2619	34/18670	9.643e-05	0.002223	0.001667	CLU/PRNP/APOE/BIN1/GSAP/SPON1/ROCK1/IFNG/IGF1/PSENEN/EPHA4/PIN1/TMED10/APH1A	14
BP	GO:0036260	RNA capping	14/2619	34/18670	9.643e-05	0.002223	0.001667	POLR2J/POLR2I/POLR2L/POLR2E/POLR2F/CMTR1/RNGTT/POLR2C/CCNH/POLR2G/ERCC2/NCBP2/MNAT1/GTF2H3	14
BP	GO:1902430	negative regulation of amyloid-beta formation	8/2619	13/18670	9.868e-05	0.002266	0.0017	CLU/PRNP/APOE/BIN1/SPON1/ROCK1/IGF1/PIN1	8
BP	GO:0002793	positive regulation of peptide secretion	64/2619	288/18670	0.0001002	0.002292	0.001719	AIM2/TREM2/JAK2/RPH3AL/RASGRP1/MAPK3/RIPK2/SEC24A/SRI/IL4R/MPC2/CD38/LILRA2/RBP4/BAD/EGFR/NLRP1/CARD8/TNFRSF14/HLA-E/HFE/HTR2B/IRF3/PTPN22/CRTAM/FGR/PTGER4/GPER1/ARRB1/F2R/POSTN/OXCT1/IFNG/SIRT3/WLS/MAPK11/CHUK/IGF1/ANG/IL6/MMP12/IL17RB/TNFSF4/HMGB1/GLMN/NOD2/ANO1/FERMT1/CD58/LPL/HIF1A/IL17RC/TARDBP/CD2/GSDMD/FCN1/TCF7L2/GOLPH3/XBP1/TLR8/EXOC1/MYH10/IL17RA/TWIST1	64
BP	GO:0030258	lipid modification	55/2619	238/18670	0.0001022	0.00233	0.001748	SPHK1/IVD/SOCS6/ECI2/ECHS1/ETFB/EPHX2/ACOX2/MTMR4/DECR2/MTMR9/MECR/SYNJ1/PIKFYVE/BDH2/APOE/PHYH/DGKA/SOCS1/MTMR6/PIK3C2B/PLA2G7/ECH1/PPARG/PEX7/HADH/ST3GAL2/PEX2/APOC1/DGKZ/ECI1/ACAT1/AGT/PIK3CB/EFR3A/SCP2/MTMR1/ALDH3A2/ACADM/ACOX1/PRKAA1/PIK3CD/FA2H/ACAA2/ACOT8/INPP5E/MCAT/CRAT/ABO/PIK3C2G/FABP3/CERK/CISH/TWIST1/PIK3CA	55
BP	GO:0006283	transcription-coupled nucleotide-excision repair	23/2619	73/18670	0.0001029	0.002338	0.001754	ERCC1/POLD2/COPS6/POLR2J/POLR2I/POLR2L/COPS7A/POLR2E/POLR2F/RPA1/COPS8/RPA3/POLD4/POLR2C/CCNH/POLR2G/UBB/PPIE/ERCC2/MNAT1/EP300/GTF2H3/RFC2	23
BP	GO:1901657	glycosyl compound metabolic process	38/2619	147/18670	0.0001038	0.002349	0.001762	AKR1B1/FUCA1/AKR1B10/NME4/TK2/NME7/GAMT/GUSB/PEMT/ENTPD4/IMPDH2/NT5C2/NME5/ADK/ADA/APOBEC3C/MACROD1/MOCS2/DPYS/DGUOK/NME3/TYMP/AKR7A2/PNP/AKR1C3/APOBEC3B/GUK1/AHCY/DNPH1/CTPS1/MPP1/TJP2/NT5E/PRPS1/AKR1C4/PRPS2/AMPD3/TH	38
BP	GO:0019319	hexose biosynthetic process	27/2619	92/18670	0.0001058	0.002377	0.001783	AKR1B1/SIK1/PDK2/SDS/GOT1/G6PC3/RBP4/SLC25A1/PGM1/ATF3/SORD/ENO2/PC/RANBP2/FAM3A/PTPN2/CHST15/MDH2/PCK2/OGT/ALDOC/KAT2B/SLC25A11/EP300/MDH1/CRY1/ATF4	27
BP	GO:0010257	NADH dehydrogenase complex assembly	21/2619	64/18670	0.0001061	0.002377	0.001783	NDUFC1/NDUFAF3/NDUFA13/NDUFS4/NDUFB4/NDUFA8/NDUFA2/TAZ/NUBPL/NDUFB6/NDUFB7/NDUFB2/NDUFA6/NDUFA10/NDUFB11/NDUFB8/NDUFA3/NDUFS3/NDUFS7/NDUFS6/NDUFA1	21
BP	GO:0032981	mitochondrial respiratory chain complex I assembly	21/2619	64/18670	0.0001061	0.002377	0.001783	NDUFC1/NDUFAF3/NDUFA13/NDUFS4/NDUFB4/NDUFA8/NDUFA2/TAZ/NUBPL/NDUFB6/NDUFB7/NDUFB2/NDUFA6/NDUFA10/NDUFB11/NDUFB8/NDUFA3/NDUFS3/NDUFS7/NDUFS6/NDUFA1	21
BP	GO:1990868	response to chemokine	28/2619	97/18670	0.0001093	0.00243	0.001823	CXCL9/CXCL10/TREM2/CCL5/CXCL13/CCL18/CXCL11/FOXC1/CX3CR1/CXCL2/CCR5/CXCR4/CCL8/RBM15/XCL1/CCR7/CXCL3/CXCR2/CCL13/HIF1A/PADI2/CIB1/CCL7/SH2B3/CXCL8/PTK2B/CCR2/CXCR6	28
BP	GO:1990869	cellular response to chemokine	28/2619	97/18670	0.0001093	0.00243	0.001823	CXCL9/CXCL10/TREM2/CCL5/CXCL13/CCL18/CXCL11/FOXC1/CX3CR1/CXCL2/CCR5/CXCR4/CCL8/RBM15/XCL1/CCR7/CXCL3/CXCR2/CCL13/HIF1A/PADI2/CIB1/CCL7/SH2B3/CXCL8/PTK2B/CCR2/CXCR6	28
BP	GO:0072524	pyridine-containing compound metabolic process	47/2619	195/18670	0.0001103	0.002443	0.001832	NUPR1/HAAO/RBKS/MPC2/CD38/NUP160/CBFA2T3/DDIT4/PNPO/ME2/NUP153/IDO1/PGM1/INSR/TPR/PRKAG1/ENO2/NUP50/SLC2A6/SEC13/RANBP2/PFKFB3/PNP/PFKM/MDH2/IFNG/DLD/IGF1/NAMPT/NUP210/NADSYN1/NCOR1/NUP43/HIF1A/PDHB/NDC1/OGT/PRKAA1/ALDOC/NT5E/EIF6/MDH1/MPC1/NUP98/RPE/ADPGK/NUP62	47
BP	GO:0019216	regulation of lipid metabolic process	85/2619	410/18670	0.0001126	0.002486	0.001865	SIK1/PDK2/SPHK1/SOCS6/FBXW7/RGL1/SNCA/PMVK/RORA/EPHX2/ABHD6/ERLIN2/SERPINA3/MTMR4/MTMR9/NCOA6/TNFRSF21/SMARCD3/APOE/CDK4/SOCS1/KIT/BCL11B/RXRA/HTR2B/MED1/ASAH1/GSTZ1/PPARG/BBS4/FGR/GPER1/FAM3A/SC5D/TAZ/PEX11A/CD81/NFKB1/IFNG/APOC1/DGKZ/WDTC1/MBTPS1/AGT/TSPO/NR1H2/PIK3R5/GHSR/EGR1/AKR1C3/PDK1/PDGFB/CD19/MTMR1/CCR7/NOD2/WDR91/DHCR7/KPNB1/ACADM/NFE2L1/NCOR1/SOD1/ACOX1/LSR/PRKAA1/CREB1/ID2/GAL/FHL2/EIF6/PLIN2/CRTC3/FABP3/PTK2B/STOML2/NFYC/PSAP/LMF1/CISH/TWIST1/RBL2/MVK/NR1D2/SORBS1	85
BP	GO:0071383	cellular response to steroid hormone stimulus	57/2619	250/18670	0.0001139	0.002499	0.001875	SFRP1/AR/JAK2/UFSP2/RORA/CFLAR/DDIT4/NCOA3/NCOA6/EGFR/TADA3/STC1/RXRA/BMP4/CYP7B1/DNAJA1/LEF1/MED1/TFPI/PPARG/KDM3A/PHB/GPER1/ARID1A/YWHAH/LMO3/DAXX/ASS1/NR1H2/NR3C2/AKR1C3/TAF7/PCK2/BUD31/CASP9/USP8/NR2F1/SSTR5/KAT5/ZFP36L2/PGRMC2/NCOR1/HDAC1/PADI2/AKAP13/RNF14/FHL2/EP300/CRY1/UBR5/NPC1/ABHD2/NR5A2/SERPINF1/KANK2/ATP2B1/NR1D2	57
BP	GO:0030099	myeloid cell differentiation	86/2619	416/18670	0.000114	0.002499	0.001875	NFKBIA/SFRP1/P4HTM/CEBPA/NBEAL2/TREM2/STAT1/JAK2/TFRC/FBXW7/LBR/ADAR/IL15/TCTA/SNRK/PRKCB/WDR61/CBFA2T3/GPR183/NCOA6/CTNNBIP1/TNFRSF11A/GPR171/IREB2/PRKX/KIT/BMP4/EPB42/LEF1/MED1/DHRS7B/PPARG/JMJD6/PTPN2/TCIRG1/CD81/RELB/IFNG/TRIB1/PTBP3/RBM15/HMGB3/MYC/CDKN1C/PML/RBPJ/TYROBP/CASP9/MFHAS1/DNASE2/ZNF16/VEGFA/CA2/SCIN/CCR7/PRKCQ/BATF/KAT6A/ARID4A/NFE2L1/SNX10/ABI1/HIF1A/AGO3/HOXA5/ERCC2/HDAC1/IFI16/CIB1/PIK3CD/CEBPG/CREB1/ID2/GLO1/SFXN1/LGALS3/KAT2B/EIF6/EP300/SH2B3/ACTN1/PTK2B/HOXA7/CEBPB/TRIM58/SBNO2	86
BP	GO:0031348	negative regulation of defense response	55/2619	239/18670	0.0001149	0.002503	0.001877	SLAMF8/TNFAIP3/RNF125/IRAK3/CD200/TNFRSF1B/FNDC4/ADAR/SMAD3/HLA-F/RORA/HLA-G/MICB/PTPRC/HGF/NMI/ADA/APOE/HLA-E/HTRA1/MAPK7/TSPAN6/SAMHD1/CD96/PPARG/GPX1/PTGER4/GPER1/FAM3A/PTPN2/ELANE/FOXF1/NFKB1/CDH5/CR1/C5orf30/IGF1/NR1H2/GHSR/GPATCH3/MMP12/MFHAS1/CUEDC2/CST7/PPM1B/SOD1/IFI16/SEC14L1/KRT1/NT5E/TYRO3/RIOK3/SERPINF1/MVK/NR1D2	55
BP	GO:0051054	positive regulation of DNA metabolic process	53/2619	228/18670	0.0001152	0.002503	0.001877	EYA2/CDC7/PARP3/SMCHD1/PRKD2/TFRC/MAPK3/ERCC1/HNRNPA2B1/NBN/ATR/DNMT1/PTPRC/TNKS2/HGF/ATM/ATF7IP/DNA2/EGFR/DDX11/DBF4/MMS19/CD28/CD40/SETMAR/FOXM1/MYC/IL6/PML/EREG/ATRX/PDGFB/HMBOX1/AURKB/HNRNPA1/TNFSF4/HMGB1/PRKCQ/RAD50/NABP2/WRN/USP9X/ERCC2/TIMELESS/BABAM1/CEBPG/CDK1/PARM1/PTK2B/HNRNPD/STOML2/RFC2/ACTR2	53
BP	GO:0050900	leukocyte migration	100/2619	499/18670	0.0001158	0.002503	0.001877	SLAMF8/CXCL9/DYSF/CXCL10/PTN/ATP1B1/TREM2/LGMN/CD200/CCL5/IL27RA/MAPK3/SLC7A5/CXCL13/PGF/PROS1/THBS4/ANGPT1/CH25H/CCL18/GYPC/CXCL11/STK10/OLR1/SLC7A11/SOS1/SDC1/GPR183/ADAM17/ITGAX/ITGAL/ITGA5/MERTK/BSG/CX3CR1/SERPINE1/ANGPT2/TNFRSF11A/ADA/TNFRSF14/PECAM1/CXCL2/KIT/CREB3/IGLV1-44/CCR5/CYP7B1/IGHM/PLVAP/SELE/PLA2G7/ROCK1/ITGB7/SLC7A6/PTGER4/CXCR4/CD44/S1PR1/ZAP70/ELANE/CD81/CCL8/LCK/PIK3CB/RAC2/NBL1/IL6/IRAK4/PDGFB/XCL1/VEGFA/P2RX4/HMGB1/CCR7/CXCL3/CXCR2/SCG2/CCL13/IGLC1/CD58/IL17RC/IL1RN/CD2/PADI2/PIK3CD/IL6R/TNFSF14/MPP1/S100A12/LGALS3/CXADR/CCL7/GOLPH3/CXCL8/PTK2B/HOXA7/CCR2/IL17RA/VEGFB/PIK3CA	100
BP	GO:0060759	regulation of response to cytokine stimulus	46/2619	190/18670	0.0001159	0.002503	0.001877	TNFAIP3/SPHK1/IRAK3/TREM2/STAT1/BIRC3/JAK2/CCL5/RIPK2/ADAR/AGPAT1/TBK1/ANGPT1/TRAF1/PTPRC/ADAM17/CARD8/BIRC2/CASP4/SOCS1/MAPK7/SAMHD1/MADD/NOL3/JAK1/MED1/IRF3/PXDN/PPARG/CXCR4/PTPN2/IFNG/CHUK/NR1H2/IL6/VRK2/TXK/AXL/MMP12/HIF1A/CYLD/IL1RN/PADI2/IKBKG/TRIM32/SH2B3	46
BP	GO:2001252	positive regulation of chromosome organization	43/2619	174/18670	0.0001163	0.002503	0.001877	MTF2/JARID2/PRKD2/MAPK3/ERCC1/HNRNPA2B1/NBN/NIPBL/ATR/WDR61/DNMT1/TNKS2/ATM/ATF7IP/DLGAP5/NAP1L2/PINK1/SART3/TPR/ING2/DDX11/SMC5/ARRB1/AUTS2/CCNB1/PML/ATRX/HMBOX1/AURKB/VEGFA/HNRNPA1/EED/PRKCQ/RAD50/PAXBP1/SFPQ/RUVBL2/NABP2/AKAP8/OGT/PIWIL2/CDK9/HNRNPD	43
BP	GO:0051047	positive regulation of secretion	88/2619	428/18670	0.0001165	0.002503	0.001877	AIM2/TREM2/JAK2/RPH3AL/RASGRP1/MAPK3/RIPK2/TACR2/SEC24A/SNCA/SRI/HLA-F/RAB27A/IL4R/MPC2/CD38/SDC1/LILRA2/RBP4/BAD/EGFR/NLRP1/PINK1/CARD8/TNFRSF11A/TNFRSF14/HLA-E/HFE/HTR2B/IRF3/PTPN22/CRTAM/FGR/PTGER4/GPER1/ARRB1/F2R/POSTN/OXCT1/IFNG/SIRT3/WLS/AGT/MAPK11/CHUK/IGF1/CHMP2A/VAMP7/ANG/IL6/CLASP1/MMP12/IL17RB/P2RX4/SCIN/PLA2R1/TNFSF4/HMGB1/GLMN/NOD2/ANO1/FERMT1/CACNB2/CD58/LPL/HIF1A/TMF1/NMB/IL17RC/TARDBP/CD2/TAC1/GSDMD/CACNA1D/CREB1/GAL/FCN1/TCF7L2/SYT1/GOLPH3/XBP1/INHBB/RAB15/TLR8/EXOC1/MYH10/IL17RA/TWIST1	88
BP	GO:0030168	platelet activation	39/2619	153/18670	0.0001173	0.002511	0.001883	MAPK3/PLCG2/PRKCB/SLC7A11/METAP1/MERTK/PRKCH/APOE/DGKA/FIBP/CD40/F8/ARRB1/F2R/HSPB1/LCK/DGKZ/ITPR2/PIK3CB/COMP/NOS3/IL6/PIK3R5/AXL/PDGFB/PRKCQ/HBB/RAF1/TYRO3/GNA14/FZD6/COL3A1/SH2B3/FLNA/LCP2/CD40LG/C1GALT1C1/TSPAN32/PIK3CA	39
BP	GO:0006066	alcohol metabolic process	77/2619	364/18670	0.0001186	0.00253	0.001897	GCH1/AKR1B1/DYSF/PNPLA4/CEBPA/SPHK1/AKR1B10/LIPC/QDPR/LBR/PLCG2/SNCA/CH25H/PMVK/GOT1/EPHX2/ALDH1A1/ERLIN2/DHRS3/PCBD1/DHRS9/PTH1R/APOL1/RBP4/SYNJ1/APOE/FDX1/CYP11A1/SORD/RXRA/CYP7B1/GK/ASAH1/SLC5A3/MOXD1/GPER1/SNX17/SC5D/AKR7A2/CAT/CLN6/GDE1/DPAGT1/NFKB1/IFNG/APOC1/NUDT11/MBTPS1/IGF1/APOL2/AKR1C3/PCK2/SULT1A2/ALDH3A2/DHDDS/ALDH1A3/PLCE1/DHCR24/DHCR7/KPNB1/NFE2L1/SOD1/PLCD1/PRKAA1/ISYNA1/CYB5R3/ACAA2/INPP5E/COQ2/LIMA1/PTK2B/AKR1C4/NPC1/NFYC/ALDH3B1/LMF1/MVK	77
BP	GO:0048638	regulation of developmental growth	74/2619	347/18670	0.0001223	0.0026	0.00195	SIX1/SFRP1/NOTCH1/DIO3/JARID2/LGMN/AR/WWC3/SEMA4D/GAMT/NIPBL/MACF1/DUSP6/SEMA4A/FOXC1/TNKS2/FTO/SEMA3A/FGF13/RBP4/ITSN2/PIM1/APOE/GSK3B/INSR/CDK4/BMP4/GDF5/FGF20/SEMA4C/EFNA5/BBS4/CXCR4/SYT17/ADRB2/RGS4/ZFPM2/MAPK11/SEMA3F/CTDP1/IGF1/TBX5/CCNB1/RND2/GHSR/RBPJ/NPY1R/VEGFA/PIN1/SEMA3E/SOD1/CTTN/GOLGA4/PPIB/TRPV2/CREB1/CDK1/GAL/STAT5A/CDKL5/GHR/SYT1/CDKN1A/ERBB4/CYFIP1/SGPL1/DSCAM/SMO/CPNE6/BCL11A/BDNF/STC2/NEDD4L/PIK3CA	74
BP	GO:2000107	negative regulation of leukocyte apoptotic process	17/2619	47/18670	0.0001233	0.002612	0.001959	CCL5/IL7R/IDO1/MERTK/ADA/CCR5/BMP4/CD27/GHSR/AXL/AURKB/CCR7/PRKCQ/NOD2/CXCR2/HIF1A/BCL10	17
BP	GO:0106106	cold-induced thermogenesis	37/2619	143/18670	0.0001245	0.002621	0.001966	NOTCH1/JAK2/HOXC10/PEMT/IL15/ALDH1A1/ABHD6/IL4R/ADAM17/ACOT13/PRKAB1/PCTP/KDM3A/CXCR4/ADRB2/HADH/GRB10/GATM/NR1H2/HCRT/RBPJ/NOVA1/VEGFA/DYNC1H1/LNPEP/DIO2/ALMS1/TLE3/OGT/TRPV2/CCR2/CEBPB/ATF4/FH/LPIN1/ZNF423/DDIT3	37
BP	GO:0120161	regulation of cold-induced thermogenesis	37/2619	143/18670	0.0001245	0.002621	0.001966	NOTCH1/JAK2/HOXC10/PEMT/IL15/ALDH1A1/ABHD6/IL4R/ADAM17/ACOT13/PRKAB1/PCTP/KDM3A/CXCR4/ADRB2/HADH/GRB10/GATM/NR1H2/HCRT/RBPJ/NOVA1/VEGFA/DYNC1H1/LNPEP/DIO2/ALMS1/TLE3/OGT/TRPV2/CCR2/CEBPB/ATF4/FH/LPIN1/ZNF423/DDIT3	37
BP	GO:0061008	hepaticobiliary system development	36/2619	138/18670	0.0001278	0.002677	0.002008	TNFAIP3/PTN/NOTCH1/CEBPA/JARID2/SOX9/FBXW7/QDPR/NIPBL/SMAD3/CFLAR/HGF/EZH2/EGFR/ADA/PRMT5/HFE/HMGCL/CSNK2B/MED1/TAF10/ACAT1/ASS1/MPST/CPS1/PCK2/LSR/TYMS/CEBPG/XBP1/KRAS/RPS6KA1/HNRNPD/CEBPB/ASNS/PIK3CA	36
BP	GO:0001818	negative regulation of cytokine production	65/2619	296/18670	0.0001281	0.002677	0.002008	TNFAIP3/GBP1/RNF125/IRAK3/TREM2/CD200/BTN2A2/IL27RA/TBK1/ANGPT1/SLAMF1/HLA-F/SYT11/PTPRC/HGF/REL/TNFRSF21/NMI/IDO1/PRNP/MERTK/CX3CR1/CARD8/CD83/HFE/WNT11/LEF1/CD96/IRF3/PTPN22/PTGER4/ARRB1/ELANE/NFKB1/TUSC2/NDRG2/RELB/IFNG/C5orf30/TIA1/TSPO/IGF1/IL6/GHSR/GPATCH3/PML/AXL/TYROBP/XCL1/SLC11A1/CUEDC2/PIN1/TNFSF4/HMGB1/HOMER3/PPM1B/KAT5/AKAP8/CYLD/UBE2L6/INHBB/TLR8/ATP2B1/TWIST1/SRGN	65
BP	GO:0046634	regulation of alpha-beta T cell activation	27/2619	93/18670	0.0001294	0.002696	0.002022	IRF1/RIPK2/MALT1/IL4R/PTPRC/HSPH1/ADA/RUNX3/TNFRSF14/CD83/HLA-E/SOCS1/HFE/CD28/RC3H2/ZAP70/PNP/CD81/CD3E/IFNG/XCL1/PRDM1/TNFSF4/HMGB1/PRKCQ/IL6R/CCR2	27
BP	GO:0002687	positive regulation of leukocyte migration	34/2619	128/18670	0.000133	0.002762	0.002072	DYSF/CXCL10/PTN/TREM2/LGMN/CCL5/MAPK3/CXCL13/PGF/THBS4/ADAM17/SERPINE1/TNFRSF14/CREB3/PLVAP/PLA2G7/ELANE/CCL8/RAC2/IL6/XCL1/VEGFA/P2RX4/HMGB1/CCR7/CXCR2/IL6R/TNFSF14/LGALS3/CCL7/CXCL8/PTK2B/CCR2/VEGFB	34
BP	GO:0002548	monocyte chemotaxis	21/2619	65/18670	0.0001363	0.002812	0.002109	SLAMF8/CXCL10/LGMN/CCL5/CCL18/SERPINE1/TNFRSF11A/CREB3/PLA2G7/CCL8/NBL1/IL6/PDGFB/XCL1/HMGB1/CCL13/IL6R/S100A12/LGALS3/CCL7/CCR2	21
BP	GO:0051225	spindle assembly	30/2619	108/18670	0.0001363	0.002812	0.002109	ASPM/HAUS3/CHEK2/KIF2A/TPX2/RACGAP1/TPR/HAUS2/MAPRE3/SPAG5/DRG1/KIF11/CHMP2A/KIF4A/CLASP1/CDC20/TUBGCP5/AURKB/DYNC1H1/BIRC5/KPNB1/NCOR1/SMC1A/CHMP1B/MAPRE2/CEP63/SPICE1/FLNA/TUBGCP2/FBXO5	30
BP	GO:0006631	fatty acid metabolic process	80/2619	383/18670	0.0001368	0.002813	0.00211	HPGDS/LTC4S/PTGS1/PDK2/CRYL1/IVD/TBXAS1/LIPC/MAPK3/THNSL2/SNCA/ECI2/ALOX5AP/ECHS1/ETFB/EPHX2/ACSM5/ACOX2/ERLIN2/PLA2G15/TECR/SLC27A6/DECR2/CES2/MECR/BDH2/PHYH/ACSL5/SLC27A5/PCCB/PRKAG1/GSTM4/PRKAB1/ECH1/HPGD/GSTZ1/PPARG/GPX1/PEX7/GPX4/HADH/PLA2G4C/PEX2/APOC1/WDTC1/ECI1/ACAT1/DLD/SCD5/NR1H2/GHSR/SCP2/AKR1C3/PDK1/PTGDS/PCK2/ALDH3A2/CYP4F11/ACADM/NFE2L1/LPL/ACOX1/PRKAA1/FA2H/ACAA2/ACOT8/MCAT/EIF6/NDUFS6/CRAT/XBP1/CBR1/SGPL1/PLP1/FABP3/AKR1C4/ABHD2/LPIN1/TH/TWIST1	80
BP	GO:0050856	regulation of T cell receptor signaling pathway	15/2619	39/18670	0.0001379	0.002826	0.00212	GBP1/PRKD2/BTN2A2/MALT1/PRNP/ADA/PTPN22/PTPN2/CD81/LCK/TRAT1/CCR7/CYLD/LGALS3/BCL10	15
BP	GO:0032495	response to muramyl dipeptide	10/2619	20/18670	0.0001391	0.002841	0.002131	TNFAIP3/NFKBIA/NOTCH1/RIPK2/NLRP1/ARHGEF2/PTPN22/LDOC1/NOD2/NOD1	10
BP	GO:0050715	positive regulation of cytokine secretion	36/2619	139/18670	0.0001495	0.003044	0.002283	AIM2/RASGRP1/MAPK3/RIPK2/IL4R/LILRA2/NLRP1/CARD8/TNFRSF14/HTR2B/IRF3/PTPN22/CRTAM/FGR/PTGER4/F2R/POSTN/IFNG/MAPK11/CHUK/MMP12/IL17RB/HMGB1/GLMN/NOD2/FERMT1/CD58/LPL/IL17RC/CD2/GSDMD/FCN1/XBP1/TLR8/IL17RA/TWIST1	36
BP	GO:0033077	T cell differentiation in thymus	22/2619	70/18670	0.0001504	0.003054	0.00229	RASGRP1/IL7R/PTPRC/SOS1/ADAM17/ADA/BCL11B/BMP4/ERBB2/CD28/JMJD6/PTPN2/ZAP70/CD3E/CD3D/CCR7/ZFP36L2/SOD1/JAG2/VNN1/CD3G/FZD7	22
BP	GO:0016051	carbohydrate biosynthetic process	50/2619	214/18670	0.0001551	0.003134	0.002351	AKR1B1/SIK1/PDK2/PPP1R3C/ENPP1/SDS/SNCA/GOT1/G6PC3/PTH1R/RBP4/SLC25A1/EGF/PGM1/EXT2/GSK3B/INSR/ATF3/SORD/B3GALNT1/DYRK2/ENO2/PC/RANBP2/GPER1/FAM3A/PTPN2/NFKB1/ST3GAL2/CHST15/MDH2/EXTL2/IGF1/PDGFB/PCK2/FUT8/OGT/HAS2/ISYNA1/ALDOC/KAT2B/SLC25A11/EP300/MDH1/CRY1/PTK2B/ATF4/CHST12/PASK/SORBS1	50
BP	GO:0045930	negative regulation of mitotic cell cycle	72/2619	338/18670	0.0001554	0.003134	0.002351	BRINP1/TOM1L1/TOPBP1/GAS1/BTN2A2/BRINP3/SKP1/NBN/RFWD3/SMAD3/CRADD/FOXC1/CHEK2/PSMB9/CHEK1/NLE1/EZH2/ATM/CDKN2C/EGFR/PTTG1/TIMP2/HECA/CDK4/CHFR/TPR/CTDSPL/BMP4/BUB1B/MAGI2/LCMT1/PSMC2/USP47/DONSON/FZD3/CDC14A/SETMAR/TPRA1/KNTC1/NDC80/MYO16/PLK2/PSMB6/CCNB1/PSMC3/TAOK1/PML/CDC20/ATRX/AURKB/PSMD8/YTHDC2/PSMB5/TOP2A/NABP2/ZFP36L2/PSMD10/TAOK3/BRINP2/GTSE1/CDK1/RAD9A/CDKN1A/WEE1/ATF2/EP300/KANK2/HMGA2/PTTG2/CENPF/RBL2/FBXO5	72
BP	GO:0002429	immune response-activating cell surface receptor signaling pathway	95/2619	473/18670	0.000156	0.003137	0.002353	GBP1/HLA-DRB4/PRKD2/BTN2A2/MAPK3/RIPK2/ARPC1A/PLCG2/SH2B2/SKP1/MALT1/BTN2A1/PRKCB/MICB/PTPRC/CD38/PSMB9/RFTN1/ITK/LILRA2/TNFRSF21/CTLA4/PRNP/BAIAP2/PRKCH/ACTR3/ADA/IGLV1-44/LAX1/BTN3A3/IGHM/PTPN22/PSMC2/CYFIP2/CD28/DENND1B/PLEKHA1/FGR/PTPN2/RC3H2/ZAP70/CD81/NFKB1/TRBC1/CD3E/CR1/RELB/LCK/PSMB6/WIPF1/TRAT1/CHUK/PIK3CB/PSMC3/CD3D/TRAC/TXK/CD247/CD19/HLA-DQB1/PSMD8/CCR7/PRKCQ/THEMIS2/PSMB5/IGLL5/IGLC1/LAT/ABI1/PSMD10/LIME1/BTN3A1/CYLD/MUC5AC/ERMAP/PIK3CD/IKBKG/RAF1/FCN1/PAK2/LGALS3/BCL10/CYFIP1/EP300/CD3G/MS4A1/KRAS/LCP2/STOML2/BTNL2/ICAM3/ACTR2/LPXN/NRAS/PIK3CA	95
BP	GO:0048871	multicellular organismal homeostasis	97/2619	485/18670	0.0001569	0.003137	0.002353	TNFAIP3/AKR1B1/NOTCH1/JAK2/HOXC10/TNFRSF11B/SOX9/TFRC/PEMT/PRKAR2A/IL15/ALDH1A1/ABHD6/SERPINA3/IL4R/CD38/FOXC1/FTO/MDM1/PTH1R/ADAM17/RBP4/BARD1/ACOT13/EGFR/NDN/LTBP3/TNFRSF11A/HFE/PRKAB1/RCN3/PCTP/GPX1/KDM3A/BBS1/BBS4/UGCG/CXCR4/TCIRG1/S1PR1/F2R/HSPB1/ADRB2/HADH/GRB10/GATM/NOS3/RAC2/NR1H2/HCRT/IL6/EGR1/ADCY1/RBPJ/SLC11A1/NOVA1/VEGFA/DYNC1H1/LNPEP/CA2/P2RX4/UBB/LIPA/NOD2/DIO2/IQCB1/SOD1/SNX10/ALMS1/TLE3/OGT/AQP2/PRKAA1/HAS2/ADCY2/TRPV2/FA2H/KRT1/CXADR/NCDN/TRIM32/CRTC3/CST4/KRAS/PTK2B/CCR2/CEBPB/ATF4/SMO/FH/LPIN1/AMPD3/ZNF423/DDIT3/PASK/NR1D2/PIK3CA	97
BP	GO:0002758	innate immune response-activating signal transduction	65/2619	298/18670	0.0001571	0.003137	0.002353	TNFAIP3/NFKBIA/RNF125/IRAK3/LGMN/IRF1/BIRC3/RIPK2/PLCG2/COLEC12/SKP1/TBK1/TRIL/MALT1/TNIP2/TNIP1/PSMB9/RFTN1/LILRA2/TNIP3/PUM2/BIRC2/TSPAN6/IRF3/PTPN22/PSMC2/ALPK1/NFKB1/PELI1/RELB/PSMB6/CHUK/S100A1/PSMC3/TLR5/GPATCH3/IRAK4/MFHAS1/PSMD8/UBB/HMGB1/NOD2/PSMB5/TRAF3/MAPKAPK2/GRAMD4/PSMD10/DDX60/CYLD/MUC5AC/NOD1/IKBKG/RAF1/SEC14L1/FCN1/PAK2/TYRO3/BCL10/EP300/MYD88/RIOK3/KRAS/TLR8/ICAM3/NRAS	65
BP	GO:1901216	positive regulation of neuron death	27/2619	94/18670	0.0001575	0.003137	0.002353	NUPR1/MAP3K5/FIS1/FBXW7/SNCA/CLU/DDIT4/ATM/BAD/MAP3K11/PRNP/NQO1/GSK3B/PPP1R13B/IFNG/DAXX/TP53BP2/UBE2M/EGR1/TYROBP/CASP9/PIN1/MCL1/AIMP2/ATF2/ATF4/DDIT3	27
BP	GO:0046486	glycerolipid metabolic process	85/2619	414/18670	0.0001587	0.003151	0.002363	PIGT/PNPLA4/SIK1/GPAA1/PNPLA6/SOCS6/LIPC/FBXW7/PLCG2/PEMT/AGPAT1/SLC22A4/PIGK/ABHD6/PLA2G2D/MTMR4/PLA2G15/PGAP2/ATM/MTMR9/SYNJ1/PIKFYVE/AGPAT5/APOE/DGKA/SLC27A5/PRDX6/PIGA/SOCS1/PIGP/DPM3/HTR2B/OSBPL8/SH3YL1/PLEKHA4/MTMR6/PIK3C2B/GK/PLA2G7/CSNK2B/PCTP/PLD1/PLEKHA1/GPX1/TAZ/CAT/SERINC5/GDE1/PLA2G4C/APOC1/DGKZ/PIK3CB/NR1H2/ANG/PIK3R5/EFR3A/CPS1/PDGFB/PCK2/MTMR1/PLA1A/PIGH/PLCE1/ACP6/LPL/PLBD1/PIGZ/PIK3CD/LPCAT4/INPP5E/PIGC/PGAP3/FABP7/PIK3C2G/FABP3/ABHD2/STOML2/LPIN1/CPNE6/SEL1L/STARD7/LMF1/CISH/CHPT1/PIK3CA	85
BP	GO:0009206	purine ribonucleoside triphosphate biosynthetic process	42/2619	171/18670	0.0001603	0.003173	0.00238	NUPR1/TREM2/NME4/NME7/NUP160/CBFA2T3/DDIT4/PID1/IMPDH2/NME5/NUP153/PGM1/PINK1/INSR/TPR/PRKAG1/ENO2/NUP50/NME3/SLC2A6/CYC1/SEC13/RANBP2/PFKFB3/TAZ/PFKM/IFNG/IGF1/NUP210/COX5B/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/ALDOC/EIF6/STOML2/NUP98/ADPGK/NUP62	42
BP	GO:0042866	pyruvate biosynthetic process	32/2619	119/18670	0.0001615	0.003185	0.002389	NUPR1/SDS/NUP160/CBFA2T3/DDIT4/NUP153/PGM1/INSR/TPR/PRKAG1/ENO2/NUP50/SLC2A6/SEC13/RANBP2/PFKFB3/PFKM/IFNG/IGF1/NUP210/NCOR1/NUP43/SRR/HIF1A/NDC1/OGT/PRKAA1/ALDOC/EIF6/NUP98/ADPGK/NUP62	32
BP	GO:0002688	regulation of leukocyte chemotaxis	31/2619	114/18670	0.0001628	0.003201	0.002401	SLAMF8/DYSF/CXCL10/PTN/LGMN/CCL5/MAPK3/CXCL13/PGF/THBS4/ADAM17/SERPINE1/CREB3/PLA2G7/RAC2/NBL1/IL6/XCL1/VEGFA/HMGB1/CCR7/CXCR2/PADI2/IL6R/TNFSF14/MPP1/CCL7/CXCL8/PTK2B/CCR2/VEGFB	31
BP	GO:0009166	nucleotide catabolic process	44/2619	182/18670	0.0001669	0.003271	0.002453	NUPR1/NUP160/CBFA2T3/DDIT4/PDE1A/ENTPD4/NT5C2/NUP153/PGM1/TDG/ADA/INSR/TPR/PRKAG1/SAMHD1/ENO2/NUP50/SLC2A6/NUDT9/GPX1/SEC13/RANBP2/PFKFB3/PNP/PFKM/IFNG/NUDT11/ACAT1/IGF1/NUP210/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/DNPH1/ALDOC/NT5E/EIF6/AMPD3/NUP98/ADPGK/NUP62	44
BP	GO:0046434	organophosphate catabolic process	56/2619	248/18670	0.0001702	0.003327	0.002495	NUPR1/PNPLA6/ENPP1/LIPC/PLCG2/ABHD6/PLA2G15/NUP160/CBFA2T3/DDIT4/PDE1A/ENTPD4/NT5C2/NUP153/SYNJ1/PGM1/TDG/ADA/INSR/PRDX6/TPR/PRKAG1/SAMHD1/ENO2/NUP50/SLC2A6/NUDT9/GPX1/SEC13/RANBP2/PFKFB3/GDE1/PNP/PLA2G4C/PFKM/IFNG/APOC1/NUDT11/ACAT1/IGF1/NUP210/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/DNPH1/ALDOC/NT5E/INPP5E/EIF6/AMPD3/NUP98/ADPGK/NUP62	56
BP	GO:0009201	ribonucleoside triphosphate biosynthetic process	43/2619	177/18670	0.0001753	0.003407	0.002555	NUPR1/TREM2/NME4/NME7/NUP160/CBFA2T3/DDIT4/PID1/IMPDH2/NME5/NUP153/PGM1/PINK1/INSR/TPR/PRKAG1/ENO2/NUP50/NME3/SLC2A6/CYC1/SEC13/RANBP2/PFKFB3/TAZ/PFKM/IFNG/IGF1/NUP210/COX5B/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/CTPS1/ALDOC/EIF6/STOML2/NUP98/ADPGK/NUP62	43
BP	GO:0060562	epithelial tube morphogenesis	69/2619	322/18670	0.0001754	0.003407	0.002555	SIX1/HOXA11/SFRP1/CXCL10/NOTCH1/FOLR1/TCTN1/AR/SOX9/PRKD2/PGF/SMAD3/ITGAX/EGF/CTNNBIP1/IFT52/NOTCH4/PRKX/RALA/BMP4/C2CD3/SEMA4C/WNT11/LEF1/CSNK2B/MED1/FZD3/BBS4/KLHL3/CXCR4/LAMA5/MICAL2/ARID1A/FOXF1/APAF1/RBM15/AGT/LRP5/SIX2/MYC/RASIP1/PML/RBPJ/EPHA4/DEAF1/VEGFA/PLXND1/ARHGAP35/GLMN/MAGED1/LGR5/CXCR2/SEMA3E/TMED2/PHACTR4/HIF1A/HOXA5/TIMELESS/SETD2/COL4A1/BCL10/FKBPL/CEP290/FZD6/KRAS/SMO/PODXL/TWIST1/FZD2	69
BP	GO:0001889	liver development	35/2619	135/18670	0.0001794	0.003463	0.002598	TNFAIP3/PTN/NOTCH1/CEBPA/JARID2/SOX9/FBXW7/QDPR/SMAD3/CFLAR/HGF/EZH2/EGFR/ADA/PRMT5/HFE/HMGCL/CSNK2B/MED1/TAF10/ACAT1/ASS1/MPST/CPS1/PCK2/LSR/TYMS/CEBPG/XBP1/KRAS/RPS6KA1/HNRNPD/CEBPB/ASNS/PIK3CA	35
BP	GO:1903322	positive regulation of protein modification by small protein conjugation or removal	35/2619	135/18670	0.0001794	0.003463	0.002598	SPHK1/BIRC3/FBXW7/RIPK2/MYCBP2/ANGPT1/MALT1/TNIP1/FANCI/NMI/PINK1/SART3/BIRC2/CHFR/BIRC7/NDFIP1/UBE2I/RNF111/PTPN22/TOLLIP/ARRB1/ADRB2/PELI1/CDC20/PIN1/UBB/NOD2/AIMP2/PSMD10/BCL10/TSPYL5/CRY1/CDK9/HSPA5/DCUN1D1	35
BP	GO:1901292	nucleoside phosphate catabolic process	45/2619	188/18670	0.0001807	0.003477	0.002608	NUPR1/ENPP1/NUP160/CBFA2T3/DDIT4/PDE1A/ENTPD4/NT5C2/NUP153/PGM1/TDG/ADA/INSR/TPR/PRKAG1/SAMHD1/ENO2/NUP50/SLC2A6/NUDT9/GPX1/SEC13/RANBP2/PFKFB3/PNP/PFKM/IFNG/NUDT11/ACAT1/IGF1/NUP210/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/DNPH1/ALDOC/NT5E/EIF6/AMPD3/NUP98/ADPGK/NUP62	45
BP	GO:0045861	negative regulation of proteolysis	76/2619	363/18670	0.0001838	0.00351	0.002633	MICAL1/BIRC3/GAS1/PROS1/SNCA/LAMP3/HERPUD1/GABARAPL2/SLPI/SERPINA3/CFLAR/SPOCK1/SERPINA1/HGF/SERPINA5/NLE1/UBE2J1/PRNP/PTTG1/TIMP2/SERPINE1/CARD8/APLP2/BIRC2/BIRC7/ITIH4/HFE/BIN1/IDE/SERPINB6/DNAJC1/TNFAIP8/NOL3/LEF1/TFPI/USP47/ROCK1/GPX1/FHIT/CRYAB/ARRB1/CD44/CR1/CD27/AGT/TRIM21/TMEM59/PML/EPHA4/VEGFA/SERPINA4/TIMP4/C4BPB/DHCR24/BIRC5/CST7/NAIP/COL6A3/SPOCK2/OGT/IFI16/NGFR/RAF1/RYBP/TNFSF14/PAK2/TIMP1/N4BP1/CST4/RPS6KA1/SERPINF1/CLEC16A/LRIG2/USP14/RNF34/CD59	76
BP	GO:0016052	carbohydrate catabolic process	47/2619	199/18670	0.0001841	0.00351	0.002633	NUPR1/CRYL1/GUSB/RBKS/ALDH1A1/NUP160/CBFA2T3/DDIT4/BAD/NUP153/PGM1/INSR/TPR/SORD/FUT1/PRKAG1/ENO2/NUP50/SLC2A6/GK/SEC13/RANBP2/PFKFB3/PYGM/MAN2B2/PFKM/IFNG/LRP5/IGF1/GM2A/NUP210/FUT8/NEU1/NCOR1/NUP43/HIF1A/GAA/NDC1/OGT/PRKAA1/ALDOC/EIF6/FUT4/NUP98/RPE/ADPGK/NUP62	47
BP	GO:0017038	protein import	47/2619	199/18670	0.0001841	0.00351	0.002633	ZIC1/NFKBIA/ECT2/ANGPT1/PEX10/CLU/SMAD3/NDUFA13/PEX19/TIMM10/NUP153/KPNA2/NPAP1/APOE/TPR/BMP4/NUP50/MED1/PEX7/RANBP2/RPAIN/CBLB/PEX2/IFNG/MBTPS1/AGT/SIX2/SNUPN/TNPO1/PML/MMP12/FERMT1/PEX12/KPNB1/PPP3CA/PEX14/TARDBP/SIX3/KPNA1/CDKN1A/SAMM50/KPNA3/FLNA/UBR5/SMO/NUP98/NUP62	47
BP	GO:0002698	negative regulation of immune effector process	32/2619	120/18670	0.000191	0.0036	0.0027	SLAMF8/RNF125/IRAK3/PARP3/ANGPT1/HLA-F/HLA-G/MICB/IL7R/IL4R/PTPRC/THOC1/HLA-E/HFE/HTRA1/TSPAN6/CD96/RC3H2/FOXF1/CR1/GPATCH3/XCL1/CUEDC2/TNFSF4/C4BPB/PPM1B/SEC14L1/LGALS3/RIOK3/IL13RA2/CCR2/CD59	32
BP	GO:0045069	regulation of viral genome replication	27/2619	95/18670	0.0001911	0.0036	0.0027	NOTCH1/SRPK1/CCL5/ADAR/FAM111A/SLPI/TNIP1/APOBEC3C/ZC3HAV1/FBXL2/CD28/ISG20/CCL8/BANF1/YTHDC2/TOP2A/PPIE/IFITM2/CCNK/IFI16/PPIB/CXCL8/NR5A2/VAPA/HMGA2/STAU1/PPIH	27
BP	GO:0051651	maintenance of location in cell	27/2619	95/18670	0.0001911	0.0036	0.0027	GPAA1/VPS13C/SKP1/SRI/CLMN/ASPM/KDELR3/ARL2/SYNE2/BARD1/UVRAG/PINK1/APOE/ANK3/BBS4/FTL/TSPO/PML/ARL2BP/SCIN/TMSB10/GAA/AKAP9/TLN2/GOLPH3/HSPA5/SRGN	27
BP	GO:0097711	ciliary basal body-plasma membrane docking	27/2619	95/18670	0.0001911	0.0036	0.0027	CETN2/TCTN1/CEP135/CNTRL/NDE1/HAUS3/TCTN3/DCTN3/HAUS2/C2CD3/SFI1/B9D1/FGFR1OP/DCTN2/TUBA4A/PCM1/CLASP1/DYNC1H1/IQCB1/CSNK1E/ALMS1/AKAP9/CDK1/CEP290/CEP63/OFD1/TCTN2	27
BP	GO:0033209	tumor necrosis factor-mediated signaling pathway	41/2619	167/18670	0.0001925	0.003611	0.002709	TNFAIP3/AIM2/NFKBIA/SPHK1/STAT1/TNFRSF1B/BIRC3/JAK2/TNFRSF11B/TRAF1/PSMB9/ADAM17/CARD8/TNFRSF11A/TNFRSF14/BIRC2/CASP4/MADD/NOL3/PLVAP/TNFRSF17/PSMC2/CD40/PTPN2/CD27/PSMB6/CARD14/CHUK/PSMC3/PSMD8/TNFSF4/PSMB5/TRAF3/TNFSF8/PSMD10/CYLD/IKBKG/TNFSF14/TRIM32/PTK2B/CD40LG	41
BP	GO:1902003	regulation of amyloid-beta formation	12/2619	28/18670	0.0001928	0.003611	0.002709	CLU/PRNP/APOE/BIN1/GSAP/SPON1/ROCK1/IFNG/IGF1/EPHA4/PIN1/TMED10	12
BP	GO:0051607	defense response to virus	54/2619	238/18670	0.0001937	0.003617	0.002713	TNFAIP3/CXCL9/GBP1/AIM2/RNF125/CXCL10/STAT1/IRF1/BIRC3/ADAR/TBK1/FAM111A/IL15/MICB/TRIM22/PTPRC/DDIT4/POLR3C/PUM2/APOBEC3C/BIRC2/HTRA1/TSPAN6/RNASE2/PRF1/SAMHD1/IRF3/ZC3HAV1/ISG20/CD40/SERINC5/IFNG/IL6/GPATCH3/PML/APOBEC3B/MMP12/TRAF3/AGBL5/PPM1B/IFITM2/DNAJC3/DDX1/DDX60/SETD2/IFI16/DDX21/SEC14L1/OAS2/RIOK3/FLNA/TLR8/EXOC1/TSPAN32	54
BP	GO:2001251	negative regulation of chromosome organization	37/2619	146/18670	0.0001964	0.003656	0.002742	MTF2/JARID2/KDM5A/ERCC1/SNCA/NBN/DNMT1/TNKS2/TRIP12/ATM/PTTG1/ATAD2B/SET/TPR/BUB1B/LCMT1/ZNF451/KDM3A/SETMAR/NDC80/DCP2/CCNB1/TAF7/CDC20/ATRX/AURKB/HNRNPA1/RAD50/TOP2A/ATAD2/MNAT1/UBR5/HMGA1/PTTG2/CENPF/TWIST1/FBXO5	37
BP	GO:0002753	cytoplasmic pattern recognition receptor signaling pathway	20/2619	62/18670	0.0001997	0.003684	0.002763	TNFAIP3/NFKBIA/RNF125/BIRC3/RIPK2/PUM2/BIRC2/TSPAN6/IRF3/PTPN22/ALPK1/GPATCH3/UBB/NOD2/DDX60/CYLD/NOD1/IKBKG/SEC14L1/RIOK3	20
BP	GO:0032623	interleukin-2 production	20/2619	62/18670	0.0001997	0.003684	0.002763	TNFAIP3/GBP1/PRKD2/RIPK2/MALT1/PTPRC/PRNP/CD83/CD28/PNP/CD3E/CD247/XCL1/SLC11A1/GLMN/PRKCQ/HOMER3/KAT5/CCR2/STOML2	20
BP	GO:0007162	negative regulation of cell adhesion	63/2619	289/18670	0.0001999	0.003684	0.002763	GBP1/NOTCH1/IRF1/SOCS6/JAK2/ADAMDEC1/BTN2A2/SEMA4D/ANGPT1/HLA-G/PLA2G2D/IL4R/LILRB2/SPOCK1/PTPRC/TNFRSF21/CTLA4/IDO1/PRNP/SERPINE1/ANGPT2/RUNX3/CORO2B/TNFRSF14/SOCS1/HFE/MAPK7/LAX1/BMP4/ERBB2/EFNA5/PTPN22/ADAM22/PTPN2/RC3H2/PELI1/POSTN/ASS1/MAP4K4/MYOC/XCL1/MMP12/VEGFA/PLXND1/TNFSF4/HMGB1/GLMN/AP1AR/SEMA3E/PRDX2/IL1RN/NF2/PLXNA1/LGALS3/CD164/FBLN1/SH2B3/HOXA7/DSCAM/FZD7/CEBPB/PODXL/LPXN	63
BP	GO:0010950	positive regulation of endopeptidase activity	43/2619	178/18670	0.0002002	0.003684	0.002763	AIM2/FAM162A/LGMN/MAP3K5/DAP/JAK2/FIS1/RIPK2/SNCA/MALT1/SMAD3/FAS/NDUFA13/CRADD/BAD/NLRP1/CARD8/CASP4/ASPH/CYFIP2/PPARG/GPER1/ARRB1/F2R/CR1/LCK/APAF1/MYC/PML/EPHA4/CASP9/CASP8AP2/HMGB1/MTCH1/EGLN3/ARL6IP5/GRAMD4/CIDEB/IFI16/NOD1/NGFR/HIP1R/BCL10	43
BP	GO:0071295	cellular response to vitamin	13/2619	32/18670	0.0002009	0.003686	0.002765	SFRP1/PTN/FOLR1/IL15/PIM1/PENK/MED1/PPARG/POSTN/FOLR2/TRIM24/KANK2/ATP2B1	13
BP	GO:0060009	Sertoli cell development	8/2619	14/18670	0.0002019	0.003693	0.00277	SOX9/SDC1/ARID4B/NTRK1/RAB13/ATRX/ARID4A/FLNA	8
BP	GO:0019362	pyridine nucleotide metabolic process	45/2619	189/18670	0.0002055	0.003737	0.002803	NUPR1/HAAO/RBKS/MPC2/CD38/NUP160/CBFA2T3/DDIT4/ME2/NUP153/IDO1/PGM1/INSR/TPR/PRKAG1/ENO2/NUP50/SLC2A6/SEC13/RANBP2/PFKFB3/PFKM/MDH2/IFNG/DLD/IGF1/NAMPT/NUP210/NADSYN1/NCOR1/NUP43/HIF1A/PDHB/NDC1/OGT/PRKAA1/ALDOC/NT5E/EIF6/MDH1/MPC1/NUP98/RPE/ADPGK/NUP62	45
BP	GO:0046496	nicotinamide nucleotide metabolic process	45/2619	189/18670	0.0002055	0.003737	0.002803	NUPR1/HAAO/RBKS/MPC2/CD38/NUP160/CBFA2T3/DDIT4/ME2/NUP153/IDO1/PGM1/INSR/TPR/PRKAG1/ENO2/NUP50/SLC2A6/SEC13/RANBP2/PFKFB3/PFKM/MDH2/IFNG/DLD/IGF1/NAMPT/NUP210/NADSYN1/NCOR1/NUP43/HIF1A/PDHB/NDC1/OGT/PRKAA1/ALDOC/NT5E/EIF6/MDH1/MPC1/NUP98/RPE/ADPGK/NUP62	45
BP	GO:0010951	negative regulation of endopeptidase activity	56/2619	250/18670	0.0002122	0.003848	0.002886	MICAL1/BIRC3/PROS1/SNCA/LAMP3/HERPUD1/SLPI/SERPINA3/CFLAR/SPOCK1/SERPINA1/HGF/SERPINA5/NLE1/PTTG1/TIMP2/SERPINE1/CARD8/APLP2/BIRC2/BIRC7/ITIH4/BIN1/SERPINB6/TNFAIP8/NOL3/LEF1/TFPI/USP47/GPX1/CRYAB/ARRB1/CD44/CR1/CD27/AGT/VEGFA/SERPINA4/TIMP4/DHCR24/BIRC5/CST7/NAIP/COL6A3/SPOCK2/IFI16/NGFR/RAF1/TNFSF14/PAK2/TIMP1/CST4/RPS6KA1/SERPINF1/USP14/RNF34	56
BP	GO:0070482	response to oxygen levels	81/2619	394/18670	0.0002141	0.003866	0.0029	SFRP1/PTN/NOTCH1/FAM162A/ATP1B1/NDNF/FIS1/APOLD1/CHCHD2/PGF/ATP6V0D1/SMAD3/DDAH1/FAS/CCNA2/RORA/CFLAR/CD38/PSMB9/CBFA2T3/DDIT4/ADAM17/ATM/HSD11B2/BAD/PDLIM1/PINK1/STC1/ANGPT2/ADA/BACH1/CDK4/BIRC2/PENK/NOL3/KCNK3/PSMC2/PPARG/CXCR4/CRYAB/CAT/POSTN/ITPR2/APAF1/PSMB6/POLG/CCNB1/PSMC3/MYC/TBL2/ANG/EGR1/PML/RBPJ/PDK1/NAMPT/AHCY/VEGFA/TXN2/PIN1/PSMD8/UBB/EGLN3/PSMB5/PSMD10/HIF1A/ERCC2/PRKAA1/SUV39H2/RAF1/ACAA2/CREB1/CDKN1A/EP300/CUL2/PTK2B/ATF4/STC2/TH/TWIST1/VEGFB	81
BP	GO:0031647	regulation of protein stability	62/2619	284/18670	0.0002144	0.003866	0.0029	ATP1B1/IFT46/FBXW7/SNCA/CLU/SMAD3/TNIP2/CHEK2/PEX19/ATF7IP/MTMR9/CTSA/CCDC88C/PRNP/USP3/PFN2/TADA3/PINK1/PIM1/CHFR/TSPAN1/DPM3/PIM2/USP47/ASPH/PHB/CRYAB/CRTAP/USP34/PRKRA/CD81/CMTM6/PEX2/NAA16/USP27X/TRIM21/IGF1/CCNH/SEC16A/TAF9B/TYROBP/EPHA4/TRIM24/PIN1/USP8/NLK/USP9X/NF2/TARDBP/PPIB/CREB1/GTSE1/HIP1R/FKBPL/CDKN1A/EP300/XBP1/FLNA/KRAS/SMO/SEL1L/NEDD4L	62
BP	GO:0001776	leukocyte homeostasis	25/2619	86/18670	0.0002212	0.003977	0.002983	TNFAIP3/SH2B2/SLC7A11/SOS1/GPR183/ADAM17/DOCK10/MERTK/ADA/TNFRSF17/TCIRG1/RC3H2/CCNB2/PIK3CB/IL6/AXL/HMGB1/CXCR2/LAT/HIF1A/PIK3CD/TNFSF14/BCL10/SH2B3/CCR2	25
BP	GO:0071236	cellular response to antibiotic	37/2619	147/18670	0.0002275	0.004069	0.003052	TNFAIP3/SPHK1/SETX/MAP3K5/ECT2/CLU/SIGMAR1/HGF/EZH2/PINK1/NQO1/FDX1/MAPK7/DDX11/EFNA5/PLEKHA1/ITPR2/DAXX/ANKZF1/IL6/EGR1/ADCY1/AXL/PDGFB/TRAP1/HNRNPA1/NET1/TIMELESS/PRKAA1/ADCY2/CDK1/ID3/CCL7/PYCR1/ACTR2/HSPA5/PSAP	37
BP	GO:0002218	activation of innate immune response	68/2619	319/18670	0.0002282	0.004069	0.003052	TNFAIP3/AIM2/NFKBIA/RNF125/IRAK3/LGMN/IRF1/BIRC3/RIPK2/PLCG2/COLEC12/SKP1/TBK1/TRIL/MALT1/TNIP2/TNIP1/PSMB9/RFTN1/LILRA2/TNIP3/PUM2/BIRC2/TSPAN6/IRF3/PTPN22/PSMC2/ALPK1/NFKB1/PELI1/RELB/PSMB6/CHUK/S100A1/PSMC3/TLR5/GPATCH3/IRAK4/MFHAS1/PSMD8/UBB/HMGB1/NOD2/PSMB5/TRAF3/MAPKAPK2/SFPQ/GRAMD4/PSMD10/DDX60/CYLD/IFI16/MUC5AC/NOD1/IKBKG/RAF1/SEC14L1/FCN1/PAK2/TYRO3/BCL10/EP300/MYD88/RIOK3/KRAS/TLR8/ICAM3/NRAS	68
BP	GO:2001235	positive regulation of apoptotic signaling pathway	43/2619	179/18670	0.0002284	0.004069	0.003052	TPD52L1/SFRP1/NUPR1/FAM162A/JAK2/FIS1/FBXW7/SMAD3/FAS/CRADD/PTPRC/BAD/NCK2/PINK1/GSK3B/ATF3/GZMB/PEA15/PPP1R13B/GPER1/PTPN2/PRKRA/YWHAH/LCK/APAF1/AGT/TP53BP2/PML/ITM2C/UBB/MAGED1/SFPQ/MCL1/SOD1/CIDEB/CYLD/RAD9A/HIP1R/PAK2/BCL10/INHBB/STYXL1/DDIT3	43
BP	GO:0006661	phosphatidylinositol biosynthetic process	31/2619	116/18670	0.0002289	0.004069	0.003052	PIGT/GPAA1/PLCG2/PIGK/MTMR4/PGAP2/ATM/MTMR9/SYNJ1/PIKFYVE/PIGA/PIGP/DPM3/HTR2B/SH3YL1/PLEKHA4/MTMR6/PIK3C2B/PLEKHA1/PIK3CB/PIK3R5/PDGFB/MTMR1/PIGH/PIGZ/PIK3CD/INPP5E/PIGC/PGAP3/PIK3C2G/PIK3CA	31
BP	GO:0034504	protein localization to nucleus	58/2619	262/18670	0.0002298	0.004074	0.003056	ZIC1/SIX1/NFKBIA/GBP2/SOX9/ECT2/SKP1/ANGPT1/SMAD3/ARL2/BARD1/NUP153/PIKFYVE/KPNA2/NPAP1/GSK3B/TPR/BMP4/OSBPL8/NUP50/MED1/BBS4/NMD3/RANBP2/RPAIN/TOR1AIP1/CBLB/IFNG/MBTPS1/AGT/SIX2/SNUPN/NOL8/TNPO1/PML/ARL2BP/MMP12/MFHAS1/PIN1/FERMT1/KPNB1/PPP3CA/WRN/BANP/NF2/TARDBP/SIX3/NGFR/GTSE1/CDK1/KPNA1/CDKN1A/KPNA3/FLNA/UBR5/SMO/NUP98/NUP62	58
BP	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	27/2619	96/18670	0.0002308	0.004076	0.003057	TAP1/HLA-C/SEC24A/HLA-F/HLA-G/HLA-A/PSMB9/HLA-B/HLA-E/HFE/IDE/SEC22B/PSMC2/SEC13/TAPBP/VAMP3/PSMB6/CHUK/PSMC3/LNPEP/PSMD8/TAP2/PSMB5/PSMD10/IKBKG/ITGB5/NCF1	27
BP	GO:0051170	import into nucleus	40/2619	163/18670	0.0002312	0.004076	0.003057	ZIC1/NFKBIA/ECT2/ANGPT1/SMAD3/NUP153/KPNA2/NPAP1/TPR/PRKAG1/BMP4/NUP50/MED1/RANBP2/RPAIN/CBLB/IFNG/MBTPS1/AGT/SIX2/SNUPN/TNPO1/PML/MMP12/HNRNPA1/FERMT1/KPNB1/PPP3CA/SNRPD2/TARDBP/SIX3/KPNA1/CDKN1A/KPNA3/FLNA/UBR5/SMO/NUP98/GEMIN2/NUP62	40
BP	GO:0034440	lipid oxidation	28/2619	101/18670	0.0002326	0.004084	0.003063	IVD/ECI2/ECHS1/ETFB/ACOX2/DECR2/MECR/BDH2/PHYH/PLA2G7/ECH1/PPARG/PEX7/HADH/PEX2/ECI1/ACAT1/SCP2/ALDH3A2/ACADM/ACOX1/PRKAA1/ACAA2/ACOT8/MCAT/CRAT/FABP3/TWIST1	28
BP	GO:0010639	negative regulation of organelle organization	81/2619	395/18670	0.000233	0.004084	0.003063	MTF2/TOM1L1/NUPR1/JARID2/KDM5A/STMN2/ERCC1/SNCA/CLU/NBN/TMOD1/LILRB2/DNMT1/TNKS2/HGF/MDM1/CHEK1/TRIP12/FGF13/ATM/PFN2/PTTG1/PINK1/CORO2B/ATAD2B/SET/TPR/CAPZA1/SEC22B/BMP4/NOL3/BUB1B/ARHGEF2/LCMT1/TMEM14A/ZNF451/GPX1/KDM3A/BBS4/SETMAR/S1PR1/NDC80/CDH5/DCP2/TSPO/IGF1/CHMP2A/CCNB1/TAOK1/TMOD2/CLASP1/FHOD3/TAF7/CDC20/MYOC/ATRX/AURKB/HNRNPA1/SCIN/RAD50/TOP2A/RAD1/TMSB10/KATNB1/PSMD10/CIB1/ACAA2/HIP1R/KAT2B/ATAD2/MNAT1/LIMA1/UBR5/STYXL1/ARFGEF1/HMGA1/PTTG2/CENPF/CLEC16A/TWIST1/FBXO5	81
BP	GO:0045017	glycerolipid biosynthetic process	56/2619	251/18670	0.0002365	0.004132	0.003099	PIGT/SIK1/GPAA1/FBXW7/PLCG2/PEMT/AGPAT1/PIGK/PLA2G2D/MTMR4/PGAP2/ATM/MTMR9/SYNJ1/PIKFYVE/AGPAT5/DGKA/PIGA/PIGP/DPM3/HTR2B/SH3YL1/PLEKHA4/MTMR6/PIK3C2B/GK/CSNK2B/PCTP/PLD1/PLEKHA1/TAZ/DGKZ/PIK3CB/NR1H2/ANG/PIK3R5/PDGFB/PCK2/MTMR1/PIGH/PLCE1/ACP6/LPL/PIGZ/PIK3CD/LPCAT4/INPP5E/PIGC/PGAP3/PIK3C2G/FABP3/LPIN1/CPNE6/STARD7/CHPT1/PIK3CA	56
BP	GO:0006635	fatty acid beta-oxidation	22/2619	72/18670	0.000237	0.004132	0.003099	IVD/ECI2/ECHS1/ETFB/ACOX2/DECR2/MECR/BDH2/ECH1/PEX7/HADH/PEX2/ECI1/ACAT1/SCP2/ACADM/ACOX1/ACAA2/ACOT8/MCAT/CRAT/TWIST1	22
BP	GO:0034605	cellular response to heat	35/2619	137/18670	0.000244	0.004242	0.003181	CXCL10/IER5/MAPK3/ATR/NUP160/ATM/HSPH1/NUP153/RPA1/GSK3B/CHORDC1/TPR/NUP50/RPA3/SEC13/RANBP2/CRYAB/DAXX/TFEC/HSPA6/HSBP1/NUP210/ANO1/BAG1/MLST8/MAPKAPK2/NUP43/NDC1/CDKN1A/EP300/HSPA2/CAMK2B/HSPA5/NUP98/NUP62	35
BP	GO:1903708	positive regulation of hemopoiesis	44/2619	185/18670	0.0002464	0.004272	0.003204	TREM2/STAT1/BTN2A2/RASGRP1/RIPK2/MALT1/IL15/HLA-G/IL7R/IL4R/LILRB2/PTPRC/FOXC1/BAD/CTNNBIP1/ADA/RUNX3/CD83/N4BP2L2/SOCS1/LEF1/MED1/IL1RL2/TOX/ZAP70/PNP/CD27/IFNG/TRIB1/AXL/TYROBP/ZNF16/CA2/SCIN/TNFSF4/HMGB1/HIF1A/HOXA5/CYLD/CREB1/ID2/VNN1/XBP1/TRIM58	44
BP	GO:0050727	regulation of inflammatory response	96/2619	485/18670	0.0002481	0.00429	0.003217	SLAMF8/TNFAIP3/NFKBIA/NUPR1/CEBPA/SPHK1/C7/TREM2/CD200/TNFRSF1B/DNASE1L3/BIRC3/JAK2/CCL5/FNDC4/PROS1/SNCA/CCL18/CLU/SMAD3/IL15/RORA/TNIP1/SUSD4/PTPRC/HGF/ATM/EGFR/NLRP1/IDO1/SERPINE1/TNFRSF11A/ADA/APOE/BIRC2/HLA-E/MAPK7/IGLV1-44/SELE/PLA2G7/CMA1/IRF3/PPARG/CD28/GPX1/IL1RL2/CFI/PHB/PTGER4/GPER1/PTPN2/ELANE/GPX4/FOXF1/CD81/NFKB1/CDH5/CR1/C5orf30/AGT/ABCC1/IGF1/VAMP7/IL6/GHSR/XCL1/CD19/MFHAS1/CUEDC2/IL17RB/TNFSF4/CCR7/C4BPB/NOD2/CST7/IGLC1/NFE2L1/SOD1/LPL/IL17RC/CYLD/TAC1/S100A12/KRT1/NT5E/TYRO3/MYD88/CCR2/CEBPB/SERPINF1/IL17RA/CFP/MVK/NR1D2/CD59/SBNO2	96
BP	GO:0002685	regulation of leukocyte migration	46/2619	196/18670	0.0002497	0.004298	0.003224	SLAMF8/DYSF/CXCL10/PTN/TREM2/LGMN/CD200/CCL5/IL27RA/MAPK3/CXCL13/PGF/THBS4/STK10/ADAM17/CX3CR1/SERPINE1/ADA/TNFRSF14/CREB3/PLVAP/PLA2G7/PTGER4/ELANE/CD81/CCL8/RAC2/NBL1/IL6/XCL1/VEGFA/P2RX4/HMGB1/CCR7/CXCR2/PADI2/IL6R/TNFSF14/MPP1/LGALS3/CCL7/CXCL8/PTK2B/HOXA7/CCR2/VEGFB	46
BP	GO:0002064	epithelial cell development	48/2619	207/18670	0.0002507	0.004298	0.003224	NOTCH1/WNT5B/AR/SOX9/TMOD1/SDC1/ARID4B/BAD/NOTCH4/STC1/RAP2C/GSK3B/PECAM1/BCL11B/BMP4/FAT1/MAGI2/TNMD/ROCK1/GPX1/PPP1R16B/CXCR4/NTRK1/CDH5/RAB13/INSM1/SIPA1L3/ATRX/PDGFB/PRDM1/GSTM3/VEGFA/ARID4A/SOD1/HIF1A/HOXA5/SIX3/TYMS/TJP2/CDKN1A/XBP1/FLNA/SLC4A7/RAP1B/SMO/GPR4/PSAP/PODXL	48
BP	GO:0006733	oxidoreduction coenzyme metabolic process	48/2619	207/18670	0.0002507	0.004298	0.003224	NUPR1/HAAO/RBKS/MPC2/CD38/NUP160/CBFA2T3/DDIT4/ME2/NUP153/IDO1/PGM1/INSR/TPR/PRKAG1/ENO2/NUP50/COQ6/SLC2A6/SEC13/RANBP2/PFKFB3/PFKM/MDH2/IFNG/DLD/IGF1/NAMPT/NUP210/NADSYN1/NCOR1/COQ9/NUP43/HIF1A/PDHB/NDC1/OGT/PRKAA1/ALDOC/NT5E/EIF6/COQ2/MDH1/MPC1/NUP98/RPE/ADPGK/NUP62	48
BP	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	34/2619	132/18670	0.0002516	0.004303	0.003227	FAM162A/MAP3K5/DAP/JAK2/FIS1/SNCA/MALT1/SMAD3/FAS/NDUFA13/CRADD/BAD/NLRP1/CARD8/CASP4/PPARG/GPER1/ARRB1/F2R/LCK/APAF1/MYC/PML/CASP9/CASP8AP2/HMGB1/MTCH1/EGLN3/ARL6IP5/GRAMD4/NOD1/NGFR/HIP1R/BCL10	34
BP	GO:0019079	viral genome replication	32/2619	122/18670	0.0002649	0.004517	0.003388	NOTCH1/SRPK1/UBP1/CCL5/ADAR/FAM111A/HTATSF1/SLPI/TNIP1/APOBEC3C/ZC3HAV1/FBXL2/CD28/ISG20/DEK/CCL8/BANF1/YTHDC2/TOP2A/PPIE/IFITM2/CCNK/IFI16/PPIB/CXCL8/PIK3C2G/NR5A2/VAPA/HMGA2/STAU1/PPIH/CXCR6	32
BP	GO:0031398	positive regulation of protein ubiquitination	31/2619	117/18670	0.0002702	0.004595	0.003447	SPHK1/BIRC3/FBXW7/RIPK2/MYCBP2/ANGPT1/MALT1/FANCI/NMI/PINK1/BIRC2/CHFR/BIRC7/NDFIP1/RNF111/PTPN22/ARRB1/ADRB2/PELI1/CDC20/PIN1/UBB/NOD2/AIMP2/PSMD10/BCL10/TSPYL5/CRY1/CDK9/HSPA5/DCUN1D1	31
BP	GO:0006606	protein import into nucleus	36/2619	143/18670	0.0002734	0.004637	0.003478	ZIC1/NFKBIA/ECT2/ANGPT1/SMAD3/NUP153/KPNA2/NPAP1/TPR/BMP4/NUP50/MED1/RANBP2/RPAIN/CBLB/IFNG/MBTPS1/AGT/SIX2/SNUPN/TNPO1/PML/MMP12/FERMT1/KPNB1/PPP3CA/TARDBP/SIX3/KPNA1/CDKN1A/KPNA3/FLNA/UBR5/SMO/NUP98/NUP62	36
BP	GO:0035710	CD4-positive, alpha-beta T cell activation	26/2619	92/18670	0.0002748	0.004649	0.003487	RIPK2/MALT1/RORA/PLA2G2D/SEMA4A/IL4R/GPR183/RUNX3/CD83/SOCS1/LEF1/PTGER4/TCIRG1/RC3H2/CD81/RELB/IFNG/LY9/IL6/XCL1/SATB1/TNFSF4/HMGB1/PRKCQ/BATF/STOML2	26
BP	GO:2001234	negative regulation of apoptotic signaling pathway	52/2619	230/18670	0.0002759	0.004655	0.003492	TNFAIP3/EYA2/AR/CLU/FAS/HERPUD1/NDUFA13/CFLAR/BCL2A1/HGF/NLE1/NME5/PINK1/CX3CR1/SERPINE1/CREB3/MAPK7/ING2/BMP4/NOL3/ARHGEF2/PEA15/DNAJA1/TMEM14A/USP47/GPX1/CD44/HSPB1/PHIP/IGF1/NOS3/TAF9B/TRAP1/SCG2/MCL1/PSMD10/FAIM/HIF1A/PRDX2/HDAC1/BCL2L2/CTTN/RAF1/ACAA2/NDUFS3/TCF7L2/VNN1/LGALS3/TRIM32/XBP1/BDNF/RNF34	52
BP	GO:0046677	response to antibiotic	69/2619	327/18670	0.0002809	0.004725	0.003544	TNFAIP3/VKORC1/SPHK1/SETX/STAT1/MAP3K5/JAK2/ECT2/PEMT/CLU/SIGMAR1/USP46/HGF/SDF4/SDC1/EZH2/RBP4/BAD/PINK1/NQO1/ADA/BIRC2/FDX1/MAPK7/DDX11/PENK/EFNA5/JAK1/UROS/HPGD/PLEKHA1/GPX1/GGH/CRYAB/CAT/CD27/OXCT1/ITPR2/RGS4/DAXX/CRHBP/CHUK/ANKZF1/IL6/EGR1/RPL10A/ADCY1/AXL/PDGFB/TRAP1/CASP9/HNRNPA1/SOD1/HBB/NET1/TIMELESS/PRKAA1/ADCY2/TYMS/CDK1/ID3/CCL7/PYCR1/PTK2B/HNRNPD/ACTR2/HSPA5/PSAP/TH	69
BP	GO:0002221	pattern recognition receptor signaling pathway	46/2619	197/18670	0.0002823	0.004725	0.003544	TNFAIP3/NFKBIA/RNF125/IRAK3/LGMN/IRF1/BIRC3/RIPK2/COLEC12/TBK1/TRIL/TNIP2/TNIP1/RFTN1/LILRA2/TNIP3/PUM2/BIRC2/TSPAN6/IRF3/PTPN22/ALPK1/PELI1/CHUK/S100A1/TLR5/GPATCH3/IRAK4/MFHAS1/UBB/HMGB1/NOD2/TRAF3/MAPKAPK2/GRAMD4/DDX60/CYLD/NOD1/IKBKG/SEC14L1/FCN1/TYRO3/BCL10/MYD88/RIOK3/TLR8	46
BP	GO:0009124	nucleoside monophosphate biosynthetic process	48/2619	208/18670	0.0002823	0.004725	0.003544	NUPR1/TREM2/TK2/NUP160/CBFA2T3/DDIT4/PID1/IMPDH2/NUP153/ADK/PGM1/PINK1/ADA/INSR/TPR/PRKAG1/ENO2/NUP50/DGUOK/SLC2A6/CYC1/SEC13/AK1/RANBP2/PFKFB3/TAZ/PFKM/IFNG/IGF1/DCTD/NUP210/COX5B/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/TYMS/ALDOC/EIF6/PRPS1/PRPS2/STOML2/AMPD3/NUP98/ADPGK/NUP62	48
BP	GO:0048193	Golgi vesicle transport	76/2619	368/18670	0.0002855	0.004765	0.003574	COPZ2/FOLR1/GAS1/GAK/BNIP1/VPS13C/PROS1/SEC24A/ARL3/TMED1/MACF1/PREPL/GABARAPL2/KDELR3/SERPINA1/KIF2A/UVRAG/RACGAP1/YIF1A/DCTN6/TMED3/DCTN3/PPP6R3/CAPZA1/LMAN2/ARL1/SEC22B/EHD3/VTI1B/ANK3/BBS1/SEC13/TAPBP/F8/ERGIC3/DCTN2/VAMP3/SNX2/TRAPPC2L/CNIH1/CENPE/TRAPPC10/KIF11/PRKCI/YIPF5/EXOC2/DYNC1I1/TEX261/SEC16A/VAMP7/KIF4A/USE1/KIF15/TRAPPC8/SORT1/MON2/DYNC1H1/AP1AR/TMED2/OPTN/GOLGB1/VAMP2/SPAST/TMED9/TMED10/RANGRF/GOLGA4/ANKRD28/GOLPH3/VAPA/EXOC1/NAPA/TRAPPC11/LMF1/AP4M1/CD59	76
BP	GO:1903706	regulation of hemopoiesis	94/2619	475/18670	0.0002885	0.004802	0.003602	SLAMF8/NFKBIA/SFRP1/P4HTM/PTN/NOTCH1/TREM2/STAT1/IRF1/BTN2A2/RASGRP1/FBXW7/RIPK2/MALT1/IL15/TCTA/HLA-G/PRKCB/IL7R/IL4R/LILRB2/WDR61/PTPRC/FOXC1/SOS1/PSMB9/BAD/CTLA4/CTNNBIP1/PIM1/GPR171/ADA/RUNX3/CD83/N4BP2L2/SOCS1/BMP4/ERBB2/PUS7/LEF1/MED1/PSMC2/CD28/IL1RL2/TOX/PTPN2/RC3H2/ZAP70/PNP/CR1/CD27/IFNG/PSMB6/TRIB1/RBM15/HMGB3/PSMC3/MYC/AXL/TYROBP/PRDM1/ZNF16/CA2/SCIN/PSMD8/TNFSF4/HMGB1/PRKCQ/PSMB5/ZFP36L2/SOD1/PSMD10/HIF1A/AGO3/HOXA5/PRDX2/HDAC1/CYLD/CD2/CIB1/TCF3/CREB1/ID2/VNN1/LGALS3/KAT2B/EIF6/EP300/XBP1/PTK2B/HOXA7/CCR2/CEBPB/TRIM58	94
BP	GO:0048011	neurotrophin TRK receptor signaling pathway	13/2619	33/18670	0.0002892	0.004802	0.003602	SOS1/DDIT4/NDN/NTRK2/NTF3/CYFIP2/NTRK1/AGT/SORT1/NGFR/RAF1/CYFIP1/BDNF	13
BP	GO:0032732	positive regulation of interleukin-1 production	19/2619	59/18670	0.000293	0.004853	0.00364	AIM2/JAK2/RIPK2/MALT1/SMAD3/LILRA2/NLRP1/CARD8/HSPB1/IFNG/EGR1/TYROBP/HMGB1/NOD2/LPL/IFI16/GSDMD/NOD1/TLR8	19
BP	GO:0002576	platelet degranulation	33/2619	128/18670	0.0003023	0.004986	0.00374	CYB5R1/MAGED2/PROS1/CLU/CTSW/SERPINA3/SERPINA1/HGF/ABCC4/EGF/SERPINE1/APLP2/CFD/ITIH4/PECAM1/VTI1B/F8/TUBA4A/CD63/IGF1/PDGFB/VEGFA/SERPINA4/TAGLN2/SOD1/GTPBP2/TIMP1/SCCPDH/ACTN1/FLNA/PSAP/VEGFB/SRGN	33
BP	GO:0060749	mammary gland alveolus development	9/2619	18/18670	0.0003034	0.004986	0.00374	AR/EGF/TNFRSF11A/FOXF1/VEGFA/HIF1A/HOXA5/ID2/ERBB4	9
BP	GO:0061377	mammary gland lobule development	9/2619	18/18670	0.0003034	0.004986	0.00374	AR/EGF/TNFRSF11A/FOXF1/VEGFA/HIF1A/HOXA5/ID2/ERBB4	9
BP	GO:0042089	cytokine biosynthetic process	32/2619	123/18670	0.0003106	0.00509	0.003818	IRF1/JAK2/TBK1/PTPRC/IGF2BP3/UBE2J1/NMI/CX3CR1/CMA1/IRF3/CD28/ELANE/HSPB1/NFKB1/CD3E/IFNG/TIA1/IL6/GHSR/EGR1/EREG/TYROBP/GLMN/PRKCQ/MAPKAPK2/NOD1/CEBPG/BCL10/INHBB/TLR8/CCR2/CEBPB	32
BP	GO:0042176	regulation of protein catabolic process	78/2619	381/18670	0.0003174	0.005175	0.003882	TNFAIP3/DYSF/NUPR1/CEBPA/NELL1/IRAK3/TREM2/TNFRSF1B/SOX9/FBXW7/MYCBP2/SNCA/CLU/LAMP3/SMAD3/HERPUD1/GABARAPL2/ATRAID/NDUFA13/CHEK2/CBFA2T3/AREL1/CTSA/BARD1/EGFR/UBE2J1/EGF/PINK1/TIMP2/APOE/GSK3B/CHFR/HFE/IDE/SEC22B/PSMC2/ROCK1/GPX1/FHIT/PHB/CHMP6/CD81/IFNG/PLK2/TRIB1/DET1/PML/EPHA4/CSNK1A1/RNF19B/PIN1/USP8/UBB/UBQLN4/GLMN/TIMP4/C4BPB/WDR91/DTL/CSNK1E/EDEM1/NFE2L1/PSMD10/TMF1/OGT/BANP/RYBP/RNF14/TIMP1/N4BP1/TRIM32/FLNA/PTK2B/CLEC16A/OAZ3/LRIG2/USP14/NEDD4L	78
BP	GO:0006006	glucose metabolic process	48/2619	209/18670	0.0003175	0.005175	0.003882	SIK1/PDK2/ENPP1/SDS/GOT1/RORA/G6PC3/RBP4/SLC25A1/BAD/PGM1/GSK3B/INSR/ATF3/IGFBP4/SORD/DYRK2/ENO2/LCMT1/PC/RANBP2/FAM3A/PTPN2/PFKM/MDH2/WDTC1/LRP5/IGF1/PDK1/NPY1R/PCK2/HECTD4/NFE2L1/PDHB/GAA/OGT/PRKAA1/ALDOC/KAT2B/SLC25A11/EP300/MDH1/CRY1/ATF4/ADPGK/PASK/PIK3CA/SORBS1	48
BP	GO:2000106	regulation of leukocyte apoptotic process	24/2619	83/18670	0.0003198	0.005201	0.003901	CCL5/IL7R/SLC7A11/ADAM17/IDO1/MERTK/ADA/BIRC7/CCR5/BMP4/CD27/PIK3CB/GHSR/AXL/AURKB/CCR7/PRKCQ/NOD2/CXCR2/HIF1A/PIK3CD/LGALS3/BCL10/CD3G	24
BP	GO:0046782	regulation of viral transcription	20/2619	64/18670	0.0003219	0.005221	0.003916	CCL5/CHD1/POLR2J/POLR2I/POLR2L/POLR2E/POLR2F/RRP1B/LEF1/POLR2C/TRIM21/CTDP1/PSMC3/POLR2G/HDAC1/TARDBP/EP300/TRIM32/CDK9/HMGA2	20
BP	GO:0070371	ERK1 and ERK2 cascade	67/2619	317/18670	0.0003252	0.005251	0.003938	GBP1/NOTCH1/TREM2/SOX9/CCL5/PRKD2/BTN2A2/RASGRP1/FBXW7/MAPK3/RIPK2/ANGPT1/CCL18/SLAMF1/DUSP6/TNIP1/CFLAR/PTPRC/GPR183/EGFR/EGF/TNFRSF11A/APOE/PRMT5/ATF3/KIT/BMP4/FGF20/ERBB2/HTR2B/MED1/PTPN22/PHB/PTGER4/GPER1/PTPN2/ARRB1/CD44/F2R/NTRK1/CCL8/NDRG2/LMO3/SIRT3/AGT/IGF1/FGF18/KDR/MYC/PDGFB/XCL1/MFHAS1/EIF3A/PIN1/HMGB1/CALCR/CCR7/NOD2/CCL13/ZFP36L2/CIB1/NOD1/CCL7/ERBB4/FBLN1/PTK2B/RAP1B	67
BP	GO:0006984	ER-nucleus signaling pathway	16/2619	46/18670	0.0003255	0.005251	0.003938	FBXW7/HERPUD1/ERLIN2/NCK2/GSK3B/ATF3/PTPN2/TMCO1/MBTPS1/ATF6/XBP1/CXCL8/ATF4/HSPA5/ASNS/DDIT3	16
BP	GO:0043470	regulation of carbohydrate catabolic process	25/2619	88/18670	0.0003271	0.005251	0.003938	NUPR1/NUP160/CBFA2T3/DDIT4/NUP153/INSR/TPR/PRKAG1/NUP50/SLC2A6/SEC13/RANBP2/PFKFB3/IFNG/IGF1/NUP210/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/EIF6/NUP98/NUP62	25
BP	GO:0061097	regulation of protein tyrosine kinase activity	25/2619	88/18670	0.0003271	0.005251	0.003938	CCL5/FBXW7/PTPRC/ADAM17/EGF/PRNP/NCK2/NTRK2/RAP2C/NEDD9/PTPN2/CHMP6/FGFR1OP/CBLB/AGT/EREG/PDGFB/EPHA4/ABI1/DOCK3/PAK2/GGNBP2/MVP/BDNF/NCF1	25
BP	GO:0002700	regulation of production of molecular mediator of immune response	35/2619	139/18670	0.0003286	0.005252	0.003939	IRAK3/PARP3/TNFRSF1B/TFRC/IL27RA/MAPK3/ANGPT1/TRIL/MALT1/HLA-F/HLA-G/IL4R/PTPRC/RBP4/THOC1/TNFRSF14/HLA-E/HFE/CD96/CD28/CD40/CD81/MZB1/IL6/XCL1/CUEDC2/TNFSF4/NOD2/DDX1/DDX21/BCL10/XBP1/IL13RA2/CCR2/CD40LG	35
BP	GO:0009062	fatty acid catabolic process	29/2619	108/18670	0.0003288	0.005252	0.003939	IVD/ECI2/ECHS1/ETFB/ACOX2/PLA2G15/DECR2/MECR/BDH2/PHYH/PCCB/ECH1/PEX7/HADH/PEX2/ECI1/ACAT1/SCP2/PCK2/ALDH3A2/ACADM/ACOX1/ACAA2/ACOT8/MCAT/CRAT/ABHD2/LPIN1/TWIST1	29
BP	GO:0032652	regulation of interleukin-1 production	28/2619	103/18670	0.0003318	0.005286	0.003965	TNFAIP3/AIM2/SPHK1/TREM2/JAK2/RIPK2/MALT1/SMAD3/LILRA2/NLRP1/CX3CR1/CARD8/F2R/HSPB1/IFNG/IGF1/GHSR/EGR1/PML/TYROBP/HMGB1/CCR7/NOD2/LPL/IFI16/GSDMD/NOD1/TLR8	28
BP	GO:0046364	monosaccharide biosynthetic process	27/2619	98/18670	0.0003327	0.005287	0.003966	AKR1B1/SIK1/PDK2/SDS/GOT1/G6PC3/RBP4/SLC25A1/PGM1/ATF3/SORD/ENO2/PC/RANBP2/FAM3A/PTPN2/CHST15/MDH2/PCK2/OGT/ALDOC/KAT2B/SLC25A11/EP300/MDH1/CRY1/ATF4	27
BP	GO:2001236	regulation of extrinsic apoptotic signaling pathway	38/2619	155/18670	0.0003337	0.00529	0.003968	TNFAIP3/SFRP1/EYA2/AR/TRAF1/FAS/CFLAR/PTPRC/HGF/DEPTOR/SERPINE1/ATF3/MAPK7/BMP4/MADD/NOL3/ARHGEF2/PEA15/GPX1/GPER1/PHIP/AGT/IGF1/NOS3/PML/ITM2C/SCG2/MCL1/FAIM/PRDX2/CYLD/CTTN/RAF1/TCF7L2/PAK2/LGALS3/BCL10/RNF34	38
BP	GO:0009266	response to temperature stimulus	54/2619	243/18670	0.0003354	0.005303	0.003978	NFKBIA/CXCL10/IER5/MAPK3/CIRBP/MICB/ATR/NUP160/ATM/HSPH1/NUP153/RPA1/GSK3B/CHORDC1/TPR/HTR2B/NUP50/DNAJA1/RPA3/PPARG/SEC13/RANBP2/CXCR4/CRYAB/ADRB2/NTRK1/DAXX/IGF1/NOS3/TFEC/HSPA6/HSBP1/NUP210/ANO1/BAG1/MLST8/MAPKAPK2/NFE2L1/SOD1/NUP43/DNAJC3/LPL/NDC1/PRKAA1/TRPV2/CDKN1A/EP300/HSPA2/CAMK2B/HSPA5/NUP98/ATP2B1/RNF34/NUP62	54
BP	GO:0019083	viral transcription	42/2619	177/18670	0.0003545	0.005591	0.004193	CCL5/CHD1/POLR2J/POLR2I/NUP160/POLR2L/NUP153/POLR2E/POLR2F/TPR/RRP1B/NUP50/LEF1/RPS8/POLR2C/RPL12/SEC13/RANBP2/RPS11/CCNT2/TRIM21/CTDP1/PSMC3/RPL10A/POLR2G/NUP210/RPS5/NUP43/RPL27A/NDC1/HDAC1/TARDBP/RPL8/RPL19/EP300/TRIM32/CDK9/RPL35A/NUP98/HMGA2/NUP62/RPLP0	42
BP	GO:0043902	positive regulation of multi-organism process	44/2619	188/18670	0.0003585	0.005634	0.004226	NOTCH1/SRPK1/CCL5/CHD1/MAPK3/RIPK2/ADAR/TBK1/POLR2J/POLR2I/POLR2L/BAD/POLR2E/POLR2F/KPNA2/PUM2/APOE/PRF1/RRP1B/LEF1/PC/CD28/POLR2C/IFNG/TRIM21/CTDP1/CHMP2A/POLR2G/LY86/YTHDC2/TOP2A/OPTN/PPIE/DDX60/CIB1/NOD1/PPIB/EP300/INHBB/CDK9/NR5A2/VAPA/STAU1/PPIH	44
BP	GO:0034341	response to interferon-gamma	46/2619	199/18670	0.000359	0.005634	0.004226	GCH1/GBP1/GBP2/HLA-C/STAT1/IRF1/JAK2/HLA-DRB4/CCL5/SNCA/CCL18/HLA-F/HLA-G/TRIM22/HLA-A/NMI/ACTR3/TRIM26/HLA-B/HLA-E/SOCS1/JAK1/MED1/IRF3/PPARG/PTPN2/CD44/CCL8/VAMP3/IFNG/ASS1/TRIM21/NR1H2/TXK/PML/XCL1/SLC11A1/HLA-DQB1/CCL13/IFITM2/CD58/RAB20/OAS2/CCL7/CAMK2B/ACTR2	46
BP	GO:0042107	cytokine metabolic process	32/2619	124/18670	0.0003632	0.005686	0.004265	IRF1/JAK2/TBK1/PTPRC/IGF2BP3/UBE2J1/NMI/CX3CR1/CMA1/IRF3/CD28/ELANE/HSPB1/NFKB1/CD3E/IFNG/TIA1/IL6/GHSR/EGR1/EREG/TYROBP/GLMN/PRKCQ/MAPKAPK2/NOD1/CEBPG/BCL10/INHBB/TLR8/CCR2/CEBPB	32
BP	GO:0006925	inflammatory cell apoptotic process	10/2619	22/18670	0.0003723	0.005814	0.004361	CCL5/SLC7A11/CCR5/IRF3/PIK3CB/IL6/GHSR/NOD2/CXCR2/PIK3CD	10
BP	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	23/2619	79/18670	0.0003791	0.005904	0.004429	TAP1/HLA-C/HLA-F/HLA-G/HLA-A/PSMB9/HLA-B/HLA-E/SEC22B/PSMC2/TAPBP/VAMP3/PSMB6/CHUK/PSMC3/LNPEP/PSMD8/TAP2/PSMB5/PSMD10/IKBKG/ITGB5/NCF1	23
BP	GO:0042752	regulation of circadian rhythm	30/2619	114/18670	0.0003818	0.005932	0.004449	SIK1/FBXW7/RORA/KDM2A/EZH2/ADA/GSK3B/PPARG/HCRTR2/ADCY1/PML/MAGEL2/PTGDS/MAGED1/CSNK1E/TOP2A/SFPQ/USP9X/TIMELESS/PRKAA1/TARDBP/SUV39H2/CREB1/CDK1/ID2/CRY1/PIWIL2/PHLPP1/HNRNPD/NR1D2	30
BP	GO:0016572	histone phosphorylation	14/2619	38/18670	0.0003869	0.005997	0.004498	JAK2/MAPK3/CCNA2/PRKCB/CHEK1/ATM/CCNB1/AURKB/AKAP8/PRKAA1/CDK1/CDK9/HMGA2/TWIST1	14
BP	GO:0071887	leukocyte apoptotic process	28/2619	104/18670	0.0003942	0.006095	0.004571	CCL5/IL7R/SLC7A11/ADAM17/TNFRSF21/IDO1/MERTK/ADA/BIRC7/CCR5/BMP4/IRF3/CD27/PIK3CB/IL6/GHSR/AXL/AURKB/CASP9/CCR7/PRKCQ/NOD2/CXCR2/HIF1A/PIK3CD/LGALS3/BCL10/CD3G	28
BP	GO:0019395	fatty acid oxidation	27/2619	99/18670	0.0003972	0.006104	0.004578	IVD/ECI2/ECHS1/ETFB/ACOX2/DECR2/MECR/BDH2/PHYH/ECH1/PPARG/PEX7/HADH/PEX2/ECI1/ACAT1/SCP2/ALDH3A2/ACADM/ACOX1/PRKAA1/ACAA2/ACOT8/MCAT/CRAT/FABP3/TWIST1	27
BP	GO:0045621	positive regulation of lymphocyte differentiation	26/2619	94/18670	0.0003977	0.006104	0.004578	BTN2A2/RASGRP1/RIPK2/MALT1/IL15/HLA-G/IL7R/IL4R/LILRB2/PTPRC/BAD/ADA/RUNX3/CD83/SOCS1/IL1RL2/TOX/ZAP70/PNP/CD27/IFNG/AXL/TNFSF4/CYLD/VNN1/XBP1	26
BP	GO:0070167	regulation of biomineral tissue development	26/2619	94/18670	0.0003977	0.006104	0.004578	PTN/NOTCH1/NELL1/SOX9/ENPP1/MGP/ANKH/SMAD3/ATRAID/LTBP3/BMP4/ROCK1/S1PR1/OSR2/ADRB2/COMP/NOS3/HIF1A/MMP20/PTK2B/CEBPB/ATF4/ATP2B1/TWIST1/SRGN/FBXO5	26
BP	GO:0006790	sulfur compound metabolic process	76/2619	372/18670	0.000401	0.00614	0.004605	HPGDS/THTPA/CBS/GSTA4/PDK2/MICAL1/NDNF/GAL3ST4/UST/BHMT2/ENPP1/GAMT/PEMT/ANGPT1/SNCA/PMVK/ACSM5/MPC2/SLC7A11/TECR/SLC25A1/B4GALT2/ACOT13/COMT/TPST1/SUOX/ACSL5/PCCB/SMS/MGST3/HMGCL/GSTM4/MMS19/GSTZ1/PC/GPX1/ESD/NUBPL/MICAL2/GPX4/MSRA/HEXA/ST3GAL2/CHST15/ACAT1/MPST/DLD/SCD5/GSTM5/CPS1/PDK1/AHCY/NUBP2/SULT1A2/GSTM3/TXN2/NFE2L1/SOD1/GGCT/PDHB/SPOCK2/SUCLG1/STAT5A/ACOT8/FAR2/NFU1/GLO1/GHR/VCAN/MPC1/CHST12/KERA/PAPSS1/ARSB/MVK/B4GALT3	76
BP	GO:0008202	steroid metabolic process	69/2619	331/18670	0.0004035	0.006162	0.004622	AKR1B1/CYB5R1/CEBPA/LGMN/LIPC/LBR/CH25H/PMVK/OSBPL3/RORA/EPHX2/ACOX2/ERLIN2/DHRS9/ATP8B1/APOL1/HSD11B2/COMT/APOE/HSD17B1/SLC27A5/FDX1/CYP11A1/KIT/RXRA/CYP7B1/STS/MED1/ASAH1/PLEKHA1/SNX17/SC5D/CAT/CLN6/NFKB1/YWHAH/IFNG/APOC1/ACAT1/MBTPS1/AGT/TSPO/UGT2B17/APOL2/SCP2/EGR1/AKR1C3/SULT1A2/LIPA/DHCR24/DHCR7/KPNB1/NFE2L1/SOD1/HSD17B14/PRKAA1/CYB5R3/ACAA2/GAL/ACOT8/LIMA1/SGPL1/AKR1C4/NPC1/NR5A2/NFYC/LMF1/MVK/ACBD3	69
BP	GO:0050854	regulation of antigen receptor-mediated signaling pathway	20/2619	65/18670	0.0004044	0.006162	0.004622	GBP1/PRKD2/BTN2A2/MALT1/PRKCB/PTPRC/PRNP/PRKCH/ADA/PTPN22/PTPN2/CD81/LCK/TRAT1/CD19/CCR7/CYLD/LGALS3/BCL10/LPXN	20
BP	GO:0009895	negative regulation of catabolic process	65/2619	308/18670	0.0004131	0.006279	0.00471	DYSF/NUPR1/NELL1/IRAK3/TREM2/DAP/MYCBP2/SNCA/LAMP3/SMAD3/CIRBP/GABARAPL2/ATRAID/HGF/CBFA2T3/DDIT4/MTMR9/CTSA/EGFR/UBE2J1/PINK1/TIMP2/HNRNPA0/RRAGA/HFE/SEC22B/HERC1/HTR2B/PTPN22/ROCK1/FHIT/PHB/POLDIP2/APOC1/TSPO/RASIP1/PML/NAMPT/EPHA4/SLC11A1/PIN1/UBQLN4/TIMP4/MAPKAPK2/DND1/MCL1/OGT/BANP/YBX1/PRKAA1/TARDBP/ATP2B4/RYBP/TIMP1/N4BP1/MYD88/CRTC3/FLNA/HNRNPD/NPC1/CLEC16A/LRIG2/USP14/DAZL/PIK3CA	65
BP	GO:0046640	regulation of alpha-beta T cell proliferation	12/2619	30/18670	0.0004179	0.006337	0.004753	IRF1/RIPK2/PTPRC/TNFRSF14/HLA-E/CD28/ZAP70/CD81/CD3E/XCL1/TNFSF4/CCR2	12
BP	GO:0009063	cellular amino acid catabolic process	32/2619	125/18670	0.0004236	0.006407	0.004806	CBS/FAH/HPD/IVD/ALDH7A1/HAAO/SDS/QDPR/THNSL2/DDAH1/GOT1/BCKDHB/PCBD1/HSD17B10/DDO/IDO1/HMGCL/GCAT/ASRGL1/GSTZ1/DDAH2/ACAT1/HDC/MPST/DLD/NOS3/AHCY/TXN2/OAT/ATP2B4/HNMT/ALDH6A1	32
BP	GO:0001659	temperature homeostasis	41/2619	173/18670	0.0004252	0.006417	0.004813	NOTCH1/JAK2/HOXC10/PEMT/IL15/ALDH1A1/ABHD6/IL4R/FTO/ADAM17/ACOT13/TNFRSF11A/PRKAB1/PCTP/GPX1/KDM3A/CXCR4/ADRB2/HADH/GRB10/GATM/NR1H2/HCRT/EGR1/RBPJ/NOVA1/VEGFA/DYNC1H1/LNPEP/DIO2/ALMS1/TLE3/OGT/TRPV2/CCR2/CEBPB/ATF4/FH/LPIN1/ZNF423/DDIT3	41
BP	GO:0120163	negative regulation of cold-induced thermogenesis	16/2619	47/18670	0.0004299	0.006448	0.004836	NOTCH1/HOXC10/IL15/ALDH1A1/ABHD6/ADAM17/ACOT13/PCTP/NR1H2/RBPJ/NOVA1/LNPEP/TLE3/ATF4/ZNF423/DDIT3	16
BP	GO:0010332	response to gamma radiation	18/2619	56/18670	0.0004303	0.006448	0.004836	CXCL10/ATR/PTPRC/CHEK2/ATM/GPX1/CRYAB/POLG/MYC/BRCA2/EGR1/PML/WRN/PRKAA1/CDKN1A/CCL7/TSPYL5/HSPA5	18
BP	GO:0090307	mitotic spindle assembly	18/2619	56/18670	0.0004303	0.006448	0.004836	CHEK2/KIF2A/TPX2/RACGAP1/TPR/DRG1/KIF11/CHMP2A/KIF4A/CLASP1/CDC20/AURKB/BIRC5/KPNB1/SMC1A/CHMP1B/SPICE1/FLNA	18
BP	GO:0072089	stem cell proliferation	31/2619	120/18670	0.0004365	0.006513	0.004885	PTN/NOTCH1/NDE1/ASPM/PTPRC/FGF13/SMARCD3/LTBP3/RACGAP1/CX3CR1/PIM1/N4BP2L2/ARHGEF2/LEF1/FZD3/ID4/EML1/SIX2/ETV6/VEGFA/FERMT1/DCT/ABCB1/HIF1A/AGO3/NF2/SIX3/BABAM1/FBLN1/SMO/HMGA2	31
BP	GO:0006260	DNA replication	59/2619	274/18670	0.0004367	0.006513	0.004885	BAZ1A/CDC7/TOPBP1/FBXW7/NBN/RFWD3/FAM111A/CCNA2/POLD2/ATR/RECQL/CHEK2/CHEK1/ATM/BARD1/NCOA6/DNA2/EGFR/ORC3/ZNF365/RPA1/THOC1/SET/RRM2/DDX11/DBF4/SAMHD1/RPA3/ORC6/POLD4/DONSON/RMI1/SETMAR/RPAIN/GINS1/POLG/NASP/HCRT/BRCA2/EREG/TOP1/ATRX/RAD50/DTL/RAD1/MCMBP/KAT5/WRN/SMC1A/TIMELESS/CDK1/ID3/RAD9A/CDK9/STOML2/RFC2/NUP98/HMGA1/FBXO5	59
BP	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	77/2619	379/18670	0.000439	0.006516	0.004887	SRPK1/SETX/HNRNPA2B1/CIRBP/CELF2/HTATSF1/MBNL3/LSM4/SNRNP40/POLR2J/POLR2I/POLR2L/KHDRBS3/POLR2E/POLR2F/DDX39A/SF3B1/PRMT5/ZMAT5/SART3/SNRNP25/PRDX6/HNRNPA0/PRPF4B/LSM3/NOL3/FAM172A/CELF1/CWF19L1/HNRNPK/POLR2C/CPSF7/DDX46/JMJD6/DDX23/SF3B5/RBM15/TIA1/SNUPN/SFSWAP/POLR2G/LSM5/SRSF4/PTBP2/BUD31/NOVA1/HNRNPA1/SRSF8/SFPQ/ZCCHC8/PPIE/SNIP1/DNAJC8/SCAF11/DDX1/SNRPD2/YBX1/RBM19/SREK1/TXNL4A/RBM41/YTHDC1/NCBP2/DAZAP1/DDX41/SON/LUC7L/UBL5/U2SURP/PUF60/HNRNPD/NUP98/CSTF2/RBMXL2/GEMIN2/PPIH/LSM2	77
BP	GO:0000398	mRNA splicing, via spliceosome	77/2619	379/18670	0.000439	0.006516	0.004887	SRPK1/SETX/HNRNPA2B1/CIRBP/CELF2/HTATSF1/MBNL3/LSM4/SNRNP40/POLR2J/POLR2I/POLR2L/KHDRBS3/POLR2E/POLR2F/DDX39A/SF3B1/PRMT5/ZMAT5/SART3/SNRNP25/PRDX6/HNRNPA0/PRPF4B/LSM3/NOL3/FAM172A/CELF1/CWF19L1/HNRNPK/POLR2C/CPSF7/DDX46/JMJD6/DDX23/SF3B5/RBM15/TIA1/SNUPN/SFSWAP/POLR2G/LSM5/SRSF4/PTBP2/BUD31/NOVA1/HNRNPA1/SRSF8/SFPQ/ZCCHC8/PPIE/SNIP1/DNAJC8/SCAF11/DDX1/SNRPD2/YBX1/RBM19/SREK1/TXNL4A/RBM41/YTHDC1/NCBP2/DAZAP1/DDX41/SON/LUC7L/UBL5/U2SURP/PUF60/HNRNPD/NUP98/CSTF2/RBMXL2/GEMIN2/PPIH/LSM2	77
BP	GO:0006096	glycolytic process	30/2619	115/18670	0.0004483	0.006597	0.004948	NUPR1/NUP160/CBFA2T3/DDIT4/NUP153/PGM1/INSR/TPR/PRKAG1/ENO2/NUP50/SLC2A6/SEC13/RANBP2/PFKFB3/PFKM/IFNG/IGF1/NUP210/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/ALDOC/EIF6/NUP98/ADPGK/NUP62	30
BP	GO:0032612	interleukin-1 production	30/2619	115/18670	0.0004483	0.006597	0.004948	TNFAIP3/AIM2/SPHK1/TREM2/JAK2/RIPK2/MALT1/SMAD3/S100A13/LILRA2/NLRP1/CX3CR1/CARD8/CMA1/F2R/HSPB1/IFNG/IGF1/GHSR/EGR1/PML/TYROBP/HMGB1/CCR7/NOD2/LPL/IFI16/GSDMD/NOD1/TLR8	30
BP	GO:0002200	somatic diversification of immune receptors	22/2619	75/18670	0.0004487	0.006597	0.004948	PARP3/DCLRE1C/TFRC/IL27RA/ADAR/ERCC1/NBN/PTPRC/TCF7/ATM/THOC1/BCL11B/SAMHD1/LEF1/CD28/CD40/PMS2P1/TNFSF4/HMGB1/BATF/TCF3/CD40LG	22
BP	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	22/2619	75/18670	0.0004487	0.006597	0.004948	TAP1/HLA-C/HLA-F/HLA-G/HLA-A/PSMB9/HLA-B/HLA-E/SEC22B/PSMC2/TAPBP/VAMP3/PSMB6/CHUK/PSMC3/PSMD8/TAP2/PSMB5/PSMD10/IKBKG/ITGB5/NCF1	22
BP	GO:0008380	RNA splicing	92/2619	469/18670	0.0004515	0.006624	0.004968	SRPK1/SETX/RBM28/HNRNPA2B1/CIRBP/CELF2/HTATSF1/MBNL3/LSM4/SNRNP40/POLR2J/POLR2I/POLR2L/KHDRBS3/THOC2/POLR2E/POLR2F/DDX39A/SF3B1/THOC1/PRMT5/ZMAT5/SART3/SNRNP25/PRDX6/HNRNPA0/ZNF638/PRPF4B/LSM3/RRP1B/AKAP17A/NOL3/FAM172A/CELF1/CWF19L1/HNRNPK/POLR2C/CPSF7/DDX46/JMJD6/DDX23/FASTK/SF3B5/PTBP3/RBM15/TIA1/SNUPN/SFSWAP/ARL6IP4/POLR2G/LSM5/SRSF4/PTBP2/BUD31/CLASRP/NOVA1/HNRNPA1/SRSF8/SFPQ/ZCCHC8/PPIE/SNIP1/DNAJC8/SCAF11/DDX1/RBM39/SNRPD2/YBX1/TARDBP/RBM19/SREK1/TXNL4A/RBM41/YTHDC1/NCBP2/DAZAP1/DDX41/LGALS3/SON/LUC7L/CLK1/UBL5/U2SURP/PUF60/HNRNPD/NUP98/CSTF2/RBMXL2/GEMIN2/RTCB/PPIH/LSM2	92
BP	GO:0000187	activation of MAPK activity	37/2619	152/18670	0.0004596	0.006727	0.005045	DUSP5/MAP3K5/MAPK3/RIPK2/DUSP6/PTPRC/HGF/EGF/MAP3K11/INSR/BIRC7/NTF3/KIT/MADD/PEA15/GNG3/CXCR4/MAP4K1/ARRB1/CD81/DAXX/MAPK11/PIK3CB/IGF1/TAOK1/UBB/PLCE1/NOD2/MAPKAPK2/SOD1/PRDX2/PRKAA1/NOD1/IKBKG/CDK1/GHR/CD40LG	37
BP	GO:0030183	B cell differentiation	33/2619	131/18670	0.0004751	0.006936	0.005203	SLAMF8/SFRP1/DCLRE1C/PLCG2/MALT1/PTPRC/GPR183/ADAM17/ATM/BAD/DOCK10/TPD52/ADA/GON4L/KIT/PTPN2/KLF6/TCIRG1/NTRK1/CD27/HMGB3/RBPJ/CD19/ZFP36L2/CYLD/TCF3/CEBPG/ID2/EP300/XBP1/MS4A1/PTK2B/CD40LG	33
BP	GO:0006643	membrane lipid metabolic process	47/2619	207/18670	0.0004777	0.006958	0.005219	FUCA1/PIGT/GPAA1/SPHK1/GAL3ST4/PRKD2/PEMT/PIGK/PLA2G15/TECR/PGAP2/CTSA/CERS6/PIGA/PRKD3/KIT/PIGP/B3GALNT1/DPM3/STS/ASAH1/CERS4/UGCG/SERINC5/CLN6/HEXA/ST3GAL2/CERS2/GM2A/ALDH3A2/PIGH/NEU1/SGMS1/PRKAA1/PIGZ/FA2H/SCCPDH/PIGC/ST8SIA2/PGAP3/SGPL1/VAPA/PSAP/ALDH3B1/CERK/TH/B4GALT3	47
BP	GO:0016042	lipid catabolic process	69/2619	333/18670	0.0004813	0.006995	0.005247	FUCA1/PNPLA4/SPHK1/AKR1B10/PNPLA6/IVD/LIPC/PLCG2/ECI2/ECHS1/ETFB/ABHD6/ACOX2/PLA2G2D/PLA2G15/DECR2/MECR/BDH2/APOE/PHYH/CDK4/PCCB/PRDX6/PLD3/PLA2G7/ECH1/STS/ASAH1/PLD1/PEX7/SNX17/GDE1/HADH/CES3/YWHAH/PLA2G4C/PEX2/APOC1/ECI1/ACAT1/SCP2/AKR1C3/GM2A/CPS1/PCK2/ALDH3A2/PLA1A/PLCE1/LIPA/NEU1/ACADM/PLCD1/LPL/HSD17B14/ACOX1/PRKAA1/PLBD1/ACAA2/ACOT8/MCAT/CRAT/FABP7/SGPL1/CRTC3/FABP3/ABHD2/LPIN1/PSAP/TWIST1	69
BP	GO:0001503	ossification	80/2619	398/18670	0.0004837	0.007013	0.00526	KAZALD1/SFRP1/PTN/NOTCH1/CEBPA/NELL1/SOX9/ENPP1/IGFBP5/SEMA4D/MAPK3/MGP/ADAR/NIPBL/ANKH/SMAD3/ATRAID/MRC2/DHRS3/FOXC1/HGF/PTH1R/EGFR/LTBP3/CTNNBIP1/EXT2/MN1/STC1/TNFRSF11A/BMP4/GDF5/PENK/WNT11/LEF1/NAB1/PSMC2/PHB/FGR/PEX7/PTGER4/CAT/TCIRG1/S1PR1/OSR2/ADRB2/ID4/NPR2/LRP5/IGF1/COMP/FGF18/SIX2/IL6/MMP13/RBPJ/CHRDL1/MYOC/SUCO/SORT1/SNX10/HIF1A/ERCC2/DDX21/TAC1/IL6R/ID2/ID3/ZBTB40/VCAN/PTK2B/CEBPB/SMO/ATP2B1/GDPD2/TWIST1/SATB2/DNAJC13/SRGN/SBNO2/FBXO5	80
BP	GO:0043467	regulation of generation of precursor metabolites and energy	38/2619	158/18670	0.0004996	0.007227	0.00542	NUPR1/COX7A1/ENPP1/SNCA/NUP160/CBFA2T3/DDIT4/NUP153/PINK1/GSK3B/INSR/TPR/IDE/PRKAG1/DYRK2/NUP50/SLC2A6/SEC13/RANBP2/PFKFB3/IFNG/IGF1/CCNB1/NUP210/TRAP1/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/CDK1/EIF6/NUP98/PASK/NUP62/PIK3CA/SORBS1	38
BP	GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	9/2619	19/18670	0.000505	0.007289	0.005467	NME5/PINK1/MAPK7/NOL3/GPX1/HSPB1/TRAP1/HIF1A/VNN1	9
BP	GO:0019080	viral gene expression	44/2619	191/18670	0.0005143	0.007397	0.005548	CCL5/CHD1/POLR2J/POLR2I/NUP160/POLR2L/NUP153/POLR2E/POLR2F/TPR/RRP1B/NUP50/LEF1/RPS8/POLR2C/RPL12/SEC13/RANBP2/RPS11/CCNT2/TRIM21/CTDP1/PSMC3/RPL10A/POLR2G/NUP210/EIF3A/RPS5/NUP43/EIF2D/RPL27A/NDC1/HDAC1/TARDBP/RPL8/RPL19/EP300/TRIM32/CDK9/RPL35A/NUP98/HMGA2/NUP62/RPLP0	44
BP	GO:0071346	cellular response to interferon-gamma	42/2619	180/18670	0.0005148	0.007397	0.005548	GBP1/GBP2/HLA-C/STAT1/IRF1/JAK2/HLA-DRB4/CCL5/CCL18/HLA-F/HLA-G/TRIM22/HLA-A/NMI/ACTR3/TRIM26/HLA-B/HLA-E/SOCS1/JAK1/MED1/IRF3/PPARG/PTPN2/CD44/CCL8/VAMP3/IFNG/ASS1/TRIM21/NR1H2/TXK/PML/XCL1/HLA-DQB1/CCL13/CD58/RAB20/OAS2/CCL7/CAMK2B/ACTR2	42
BP	GO:0006757	ATP generation from ADP	30/2619	116/18670	0.0005248	0.007523	0.005642	NUPR1/NUP160/CBFA2T3/DDIT4/NUP153/PGM1/INSR/TPR/PRKAG1/ENO2/NUP50/SLC2A6/SEC13/RANBP2/PFKFB3/PFKM/IFNG/IGF1/NUP210/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/ALDOC/EIF6/NUP98/ADPGK/NUP62	30
BP	GO:0038179	neurotrophin signaling pathway	14/2619	39/18670	0.0005263	0.007528	0.005646	SOS1/DDIT4/NDN/NTRK2/NTF3/MAGI2/CYFIP2/NTRK1/AGT/SORT1/NGFR/RAF1/CYFIP1/BDNF	14
BP	GO:0050000	chromosome localization	22/2619	76/18670	0.000549	0.007779	0.005835	NDE1/ATM/DLGAP5/ACTR3/SPAG5/CDCA8/CHMP6/NDC80/CENPE/CHMP2A/CCNB1/MIS12/DYNC1H1/KPNB1/KATNB1/CHMP1B/CENPC/SPICE1/ACTR2/NUP98/CENPF/NUP62	22
BP	GO:0072329	monocarboxylic acid catabolic process	33/2619	132/18670	0.0005496	0.007779	0.005835	FAH/CRYL1/IVD/ECI2/ECHS1/ETFB/ACOX2/PLA2G15/DECR2/MECR/BDH2/PHYH/PCCB/SORD/ECH1/ASRGL1/PEX7/HADH/PEX2/ECI1/ACAT1/SCP2/PCK2/ALDH3A2/ACADM/ACOX1/ACAA2/ACOT8/MCAT/CRAT/ABHD2/LPIN1/TWIST1	33
BP	GO:0002456	T cell mediated immunity	28/2619	106/18670	0.0005506	0.007779	0.005835	HLA-C/TNFRSF1B/MALT1/HLA-F/HLA-G/MICB/IL7R/HLA-A/RAB27A/PTPRC/RFTN1/CD8A/HLA-B/HLA-E/HFE/PRF1/BTN3A3/DENND1B/CD81/IL6/XCL1/SLC11A1/TNFSF4/HMGB1/ULBP2/EMP2/CCR2/FBXO38	28
BP	GO:1901606	alpha-amino acid catabolic process	28/2619	106/18670	0.0005506	0.007779	0.005835	CBS/FAH/HPD/IVD/ALDH7A1/HAAO/SDS/QDPR/THNSL2/DDAH1/GOT1/PCBD1/DDO/IDO1/HMGCL/GCAT/ASRGL1/GSTZ1/DDAH2/ACAT1/HDC/DLD/NOS3/AHCY/OAT/ATP2B4/HNMT/ALDH6A1	28
BP	GO:0006914	autophagy	96/2619	496/18670	0.0005513	0.007779	0.005835	NUPR1/TREM2/DAP/FIS1/FBXW7/MAPK3/RIPK2/VPS13C/GABARAPL1/TBK1/SNCA/CLU/LAMP3/ATP6V0D1/GABARAPL2/VPS37C/TRIM22/UCHL1/HGF/ATM/MTMR9/CTSA/BAD/PIKFYVE/UVRAG/PINK1/GSK3B/DRAM1/CAPNS1/RRAGA/PRKAG1/SEC22B/EXOC7/PRKAB1/HERC1/HTR2B/PIK3C2B/CSNK2B/PTPN22/PIM2/FBXL2/ROCK1/TOLLIP/POLDIP2/KLHL3/SUPT20H/CHMP6/TCIRG1/HSPB1/ADRB2/ATG2B/VPS16/IFNG/PLK2/TRIM21/PIK3CB/TSPO/CHMP2A/KDR/TMEM59/RASIP1/TRAPPC8/NAMPT/MTDH/HMGB1/UBQLN4/ATP6V0E2/ATG13/LAMTOR2/MLST8/OPTN/MCL1/KAT5/HIF1A/TPCN1/MCOLN1/PRKAA1/IFI16/ANXA7/ATG4A/CTTN/NOD1/IKBKG/RRAGD/ATG12/EP300/XBP1/SESN1/NPC1/EXOC1/GABARAP/PSAP/CLEC16A/DDIT3/ARSB/PIK3CA	96
BP	GO:0061919	process utilizing autophagic mechanism	96/2619	496/18670	0.0005513	0.007779	0.005835	NUPR1/TREM2/DAP/FIS1/FBXW7/MAPK3/RIPK2/VPS13C/GABARAPL1/TBK1/SNCA/CLU/LAMP3/ATP6V0D1/GABARAPL2/VPS37C/TRIM22/UCHL1/HGF/ATM/MTMR9/CTSA/BAD/PIKFYVE/UVRAG/PINK1/GSK3B/DRAM1/CAPNS1/RRAGA/PRKAG1/SEC22B/EXOC7/PRKAB1/HERC1/HTR2B/PIK3C2B/CSNK2B/PTPN22/PIM2/FBXL2/ROCK1/TOLLIP/POLDIP2/KLHL3/SUPT20H/CHMP6/TCIRG1/HSPB1/ADRB2/ATG2B/VPS16/IFNG/PLK2/TRIM21/PIK3CB/TSPO/CHMP2A/KDR/TMEM59/RASIP1/TRAPPC8/NAMPT/MTDH/HMGB1/UBQLN4/ATP6V0E2/ATG13/LAMTOR2/MLST8/OPTN/MCL1/KAT5/HIF1A/TPCN1/MCOLN1/PRKAA1/IFI16/ANXA7/ATG4A/CTTN/NOD1/IKBKG/RRAGD/ATG12/EP300/XBP1/SESN1/NPC1/EXOC1/GABARAP/PSAP/CLEC16A/DDIT3/ARSB/PIK3CA	96
BP	GO:0036293	response to decreased oxygen levels	75/2619	370/18670	0.000554	0.0078	0.00585	SFRP1/PTN/NOTCH1/FAM162A/ATP1B1/NDNF/FIS1/APOLD1/CHCHD2/PGF/SMAD3/DDAH1/CCNA2/RORA/CFLAR/CD38/PSMB9/CBFA2T3/DDIT4/ADAM17/ATM/HSD11B2/BAD/PDLIM1/PINK1/STC1/ANGPT2/ADA/BACH1/BIRC2/PENK/NOL3/KCNK3/PSMC2/CXCR4/CRYAB/CAT/POSTN/ITPR2/APAF1/PSMB6/CCNB1/PSMC3/MYC/TBL2/ANG/EGR1/PML/RBPJ/PDK1/NAMPT/AHCY/VEGFA/TXN2/PIN1/PSMD8/UBB/EGLN3/PSMB5/PSMD10/HIF1A/ERCC2/PRKAA1/SUV39H2/RAF1/ACAA2/CREB1/EP300/CUL2/PTK2B/ATF4/STC2/TH/TWIST1/VEGFB	75
BP	GO:0000375	RNA splicing, via transesterification reactions	77/2619	382/18670	0.0005601	0.007868	0.005901	SRPK1/SETX/HNRNPA2B1/CIRBP/CELF2/HTATSF1/MBNL3/LSM4/SNRNP40/POLR2J/POLR2I/POLR2L/KHDRBS3/POLR2E/POLR2F/DDX39A/SF3B1/PRMT5/ZMAT5/SART3/SNRNP25/PRDX6/HNRNPA0/PRPF4B/LSM3/NOL3/FAM172A/CELF1/CWF19L1/HNRNPK/POLR2C/CPSF7/DDX46/JMJD6/DDX23/SF3B5/RBM15/TIA1/SNUPN/SFSWAP/POLR2G/LSM5/SRSF4/PTBP2/BUD31/NOVA1/HNRNPA1/SRSF8/SFPQ/ZCCHC8/PPIE/SNIP1/DNAJC8/SCAF11/DDX1/SNRPD2/YBX1/RBM19/SREK1/TXNL4A/RBM41/YTHDC1/NCBP2/DAZAP1/DDX41/SON/LUC7L/UBL5/U2SURP/PUF60/HNRNPD/NUP98/CSTF2/RBMXL2/GEMIN2/PPIH/LSM2	77
BP	GO:0033108	mitochondrial respiratory chain complex assembly	26/2619	96/18670	0.0005664	0.007904	0.005928	NDUFC1/NDUFAF3/NDUFA13/NDUFS4/NDUFB4/UQCR10/NDUFA8/SCO2/UQCC1/NDUFA2/TAZ/NUBPL/NDUFB6/NDUFB7/NDUFB2/NDUFA6/NDUFA10/COA3/NDUFB11/NDUFB8/NDUFA3/NDUFS3/NDUFS7/NDUFS6/SAMM50/NDUFA1	26
BP	GO:0045070	positive regulation of viral genome replication	13/2619	35/18670	0.0005672	0.007904	0.005928	NOTCH1/SRPK1/CCL5/ADAR/CD28/YTHDC2/TOP2A/PPIE/PPIB/NR5A2/VAPA/STAU1/PPIH	13
BP	GO:1904031	positive regulation of cyclin-dependent protein kinase activity	13/2619	35/18670	0.0005672	0.007904	0.005928	ADAM17/EGFR/CKS1B/MAPRE3/CKS2/CCNT2/CCNB1/PDGFB/PSMD10/CCNK/CCND2/CDKN1A/MNAT1	13
BP	GO:0030101	natural killer cell activation	24/2619	86/18670	0.0005677	0.007904	0.005928	IL21R/RASGRP1/ELF4/IL15/HLA-F/MICB/RAB27A/PTPRC/MERTK/SLAMF7/HLA-E/PTPN22/TOX/TUSC2/VAMP7/AXL/TYROBP/PRDM1/ULBP2/CD2/PIK3CD/IL6R/ID2/TYRO3	24
BP	GO:0043434	response to peptide hormone	86/2619	436/18670	0.000569	0.007904	0.005928	PTPRE/PDK2/STAT1/JAK2/ENPP1/IGFBP5/QDPR/SH2B2/PRKAR2A/ATP6V0D1/GOT1/CCNA2/PRKCB/CFLAR/SOS1/PID1/HSD11B2/BAIAP2/BSG/GSK3B/INSR/CDK4/SOCS1/CYP11A1/IDE/OSBPL8/PPARG/ROCK1/CYC1/GPER1/GGH/PTPN2/CAT/TCIRG1/HADH/NFKB1/GRB10/STAT4/MZB1/PHIP/WDTC1/AGT/ASS1/CRHBP/CHUK/PRKCI/RAB13/GHSR/EGR1/ADCY1/CPS1/EREG/SRSF4/PCK2/SORT1/CA2/ATP6V0E2/TIMP4/PRKCQ/VAMP2/LPL/AGRP/OGT/PRKAA1/ADCY2/CREB1/GAL/STAT5A/GHR/KAT2B/TIMP1/EIF6/CYFIP1/XBP1/CRY1/INHBB/FABP3/RAP1B/LPIN1/REG3A/STC2/CISH/ATP2B1/TH/PIK3CA/SORBS1	86
BP	GO:0007599	hemostasis	70/2619	341/18670	0.0005784	0.008018	0.006014	VKORC1/MICAL1/IRF1/JAK2/MAPK3/PHF21A/PLCG2/PROS1/SH2B2/PRKAR2A/PRKCB/RAB27A/SLC7A11/SERPINA1/METAP1/SERPINA5/MERTK/SERPINE1/PRKCH/APOE/DGKA/CAPZA1/EHD3/FIBP/TFPI/CD40/F8/ARRB1/F2R/HSPB1/LCK/DGKZ/ITPR2/MAFF/ZFPM2/PIK3CB/COMP/NOS3/GGCX/IL6/PIK3R5/AXL/PDGFB/P2RX4/RAD51C/C4BPB/PRKCQ/CYP4F11/HBB/RCOR1/PRDX2/HDAC1/ANXA7/RAF1/HPS5/KRT1/TYRO3/GNA14/FZD6/FBLN1/COL3A1/SH2B3/FLNA/LCP2/CD40LG/C1GALT1C1/RAD51B/TSPAN32/PIK3CA/CD59	70
BP	GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus	19/2619	62/18670	0.0005915	0.008163	0.006123	PARP3/DCLRE1C/TFRC/IL27RA/ERCC1/NBN/PTPRC/TCF7/ATM/THOC1/BCL11B/LEF1/CD28/CD40/TNFSF4/HMGB1/BATF/TCF3/CD40LG	19
BP	GO:0016444	somatic cell DNA recombination	19/2619	62/18670	0.0005915	0.008163	0.006123	PARP3/DCLRE1C/TFRC/IL27RA/ERCC1/NBN/PTPRC/TCF7/ATM/THOC1/BCL11B/LEF1/CD28/CD40/TNFSF4/HMGB1/BATF/TCF3/CD40LG	19
BP	GO:0001666	response to hypoxia	73/2619	359/18670	0.0005934	0.008172	0.006129	SFRP1/PTN/NOTCH1/FAM162A/ATP1B1/NDNF/FIS1/APOLD1/CHCHD2/PGF/SMAD3/DDAH1/CCNA2/RORA/CFLAR/CD38/PSMB9/CBFA2T3/DDIT4/ADAM17/ATM/HSD11B2/BAD/PDLIM1/PINK1/STC1/ANGPT2/ADA/BACH1/BIRC2/PENK/NOL3/KCNK3/PSMC2/CXCR4/CRYAB/CAT/POSTN/ITPR2/APAF1/PSMB6/CCNB1/PSMC3/MYC/TBL2/ANG/EGR1/PML/RBPJ/PDK1/AHCY/VEGFA/TXN2/PIN1/PSMD8/UBB/EGLN3/PSMB5/PSMD10/HIF1A/ERCC2/PRKAA1/SUV39H2/RAF1/ACAA2/CREB1/EP300/CUL2/PTK2B/STC2/TH/TWIST1/VEGFB	73
BP	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity	12/2619	31/18670	0.0005955	0.008182	0.006137	ADAM17/EGFR/CKS1B/MAPRE3/CKS2/CCNT2/CCNB1/PDGFB/PSMD10/CCNK/CCND2/MNAT1	12
BP	GO:0032102	negative regulation of response to external stimulus	74/2619	365/18670	0.0005974	0.008191	0.006144	SLAMF8/TNFAIP3/RNF125/NOTCH1/CD200/TNFRSF1B/SEMA4D/FNDC4/CXCL13/PROS1/CHD8/SMAD3/RORA/MICB/SEMA4A/PTPRC/HGF/SEMA3A/LILRA2/SERPINE1/ANGPT2/CARD8/ADA/APOE/HTRA1/MAPK7/TSPAN6/SEMA4C/TFPI/PPARG/GPX1/BBS4/PTGER4/GPER1/FAM3A/PTPN2/ELANE/FOXF1/NFKB1/CDH5/CERS2/TRIB1/C5orf30/KLK8/SEMA3F/IGF1/NOS3/NBL1/GHSR/CLASP1/GPATCH3/PDGFB/EPHA4/MFHAS1/CUEDC2/CST7/SEMA3E/PPM1B/SOD1/PRDX2/PADI2/SEC14L1/KRT1/NT5E/TYRO3/CDKN1A/SH2B3/FABP7/RIOK3/SERPINF1/KANK2/LRIG2/MVK/NR1D2	74
BP	GO:1990845	adaptive thermogenesis	37/2619	154/18670	0.0006001	0.008203	0.006153	NOTCH1/JAK2/HOXC10/PEMT/IL15/ALDH1A1/ABHD6/IL4R/ADAM17/ACOT13/PRKAB1/PCTP/KDM3A/CXCR4/ADRB2/HADH/GRB10/GATM/NR1H2/HCRT/RBPJ/NOVA1/VEGFA/DYNC1H1/LNPEP/DIO2/ALMS1/TLE3/OGT/TRPV2/CCR2/CEBPB/ATF4/FH/LPIN1/ZNF423/DDIT3	37
BP	GO:0045666	positive regulation of neuron differentiation	75/2619	371/18670	0.000601	0.008203	0.006153	BRINP1/PTN/SCN1B/SETX/NDNF/ECT2/STMN2/SEMA4D/BRINP3/MACF1/CFLAR/HGF/MMD/SS18L1/EZH2/TUBB2B/ITSN2/NAP1L2/BAIAP2/TIMP2/NTRK2/APOE/BMP4/GDF5/FGF20/EFNA5/TMEM30A/MAGI2/ARHGEF2/TRAK1/GDPD5/PARP6/CXCR4/SYT17/NTRK1/AGT/PRKCI/NBL1/VAMP7/RND2/EPHA4/VEGFA/PLXND1/TGIF2/ARHGAP35/TENM3/CSNK1E/CAMK1/KATNB1/ZC4H2/BRINP2/GOLGA4/NGFR/TCF3/TRPV2/CDKL5/PLXNA1/SYT1/CYFIP1/EP300/TRIM32/CAPRIN2/PTK2B/STYXL1/DSCAM/FBXO38/C21orf91/SERPINF1/CAMK2B/ACTR2/HSPA5/CPNE6/BDNF/ARSB/NEDD4L	75
BP	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	11/2619	27/18670	0.0006023	0.008203	0.006153	CDC25B/CDC7/SMARCD3/CDK4/CCNB1/RAD51C/DTL/CDK1/HSPA2/RAD51B/FBXO5	11
BP	GO:0009408	response to heat	41/2619	176/18670	0.000617	0.008386	0.00629	CXCL10/IER5/MAPK3/MICB/ATR/NUP160/ATM/HSPH1/NUP153/RPA1/GSK3B/CHORDC1/TPR/NUP50/DNAJA1/RPA3/SEC13/RANBP2/CRYAB/DAXX/IGF1/NOS3/TFEC/HSPA6/HSBP1/NUP210/ANO1/BAG1/MLST8/MAPKAPK2/SOD1/NUP43/NDC1/TRPV2/CDKN1A/EP300/HSPA2/CAMK2B/HSPA5/NUP98/NUP62	41
BP	GO:0007596	blood coagulation	69/2619	336/18670	0.0006235	0.008457	0.006343	VKORC1/MICAL1/IRF1/JAK2/MAPK3/PHF21A/PLCG2/PROS1/SH2B2/PRKAR2A/PRKCB/RAB27A/SLC7A11/SERPINA1/METAP1/SERPINA5/MERTK/SERPINE1/PRKCH/APOE/DGKA/CAPZA1/EHD3/FIBP/TFPI/CD40/F8/ARRB1/F2R/HSPB1/LCK/DGKZ/ITPR2/MAFF/ZFPM2/PIK3CB/COMP/NOS3/GGCX/IL6/PIK3R5/AXL/PDGFB/P2RX4/RAD51C/C4BPB/PRKCQ/CYP4F11/HBB/RCOR1/PRDX2/HDAC1/RAF1/HPS5/KRT1/TYRO3/GNA14/FZD6/FBLN1/COL3A1/SH2B3/FLNA/LCP2/CD40LG/C1GALT1C1/RAD51B/TSPAN32/PIK3CA/CD59	69
BP	GO:0042108	positive regulation of cytokine biosynthetic process	20/2619	67/18670	0.0006259	0.008466	0.00635	IRF1/JAK2/TBK1/PTPRC/CD28/ELANE/HSPB1/CD3E/IFNG/IL6/EGR1/EREG/TYROBP/GLMN/PRKCQ/MAPKAPK2/CEBPG/BCL10/TLR8/CCR2	20
BP	GO:1902105	regulation of leukocyte differentiation	58/2619	272/18670	0.0006275	0.008466	0.00635	SLAMF8/SFRP1/TREM2/IRF1/BTN2A2/RASGRP1/FBXW7/RIPK2/MALT1/IL15/TCTA/HLA-G/IL7R/IL4R/LILRB2/PTPRC/SOS1/BAD/CTLA4/CTNNBIP1/ADA/RUNX3/CD83/SOCS1/BMP4/ERBB2/LEF1/CD28/IL1RL2/TOX/PTPN2/RC3H2/ZAP70/PNP/CR1/CD27/IFNG/TRIB1/HMGB3/MYC/AXL/TYROBP/PRDM1/CA2/TNFSF4/HMGB1/ZFP36L2/SOD1/PRDX2/CYLD/CD2/CREB1/ID2/VNN1/XBP1/HOXA7/CCR2/CEBPB	58
BP	GO:0050868	negative regulation of T cell activation	29/2619	112/18670	0.0006311	0.008466	0.00635	IRF1/SOCS6/BTN2A2/HLA-G/PLA2G2D/IL4R/LILRB2/TNFRSF21/CTLA4/IDO1/PRNP/RUNX3/TNFRSF14/SOCS1/HFE/LAX1/BMP4/ERBB2/PTPN22/PTPN2/RC3H2/PELI1/XCL1/TNFSF4/HMGB1/GLMN/PRDX2/LGALS3/CEBPB	29
BP	GO:1903900	regulation of viral life cycle	36/2619	149/18670	0.0006318	0.008466	0.00635	NOTCH1/SRPK1/CCL5/ADAR/LAMP3/FAM111A/SLPI/TNIP1/KPNA2/APOBEC3C/TRIM26/ZC3HAV1/FBXL2/PC/CD28/ISG20/CCL8/BANF1/TRIM21/CHMP2A/PML/YTHDC2/TOP2A/PPIE/IFITM2/CCNK/IFI16/PPIB/FCN1/TRIM32/CXCL8/NR5A2/VAPA/HMGA2/STAU1/PPIH	36
BP	GO:0000186	activation of MAPKK activity	17/2619	53/18670	0.0006327	0.008466	0.00635	MAP3K5/JAK2/MAPK3/RIPK2/TNIK/EGFR/EGF/MAP3K11/BMP4/F2R/MAP3K8/NTRK1/TAOK1/LAMTOR2/MAP3K3/TAOK3/RAF1	17
BP	GO:0006968	cellular defense response	17/2619	53/18670	0.0006327	0.008466	0.00635	CXCL9/HLA-G/LILRB2/ITK/CX3CR1/CCR5/PRF1/IL1RL2/TCIRG1/TRAT1/GNLY/TYROBP/CXCR2/BCL10/PTK2B/CCR2/NCF1	17
BP	GO:0042987	amyloid precursor protein catabolic process	15/2619	44/18670	0.0006337	0.008466	0.00635	CLU/PRNP/APOE/BIN1/GSAP/SPON1/ROCK1/IFNG/IGF1/PSENEN/EPHA4/PIN1/DHCR24/TMED10/APH1A	15
BP	GO:1901987	regulation of cell cycle phase transition	93/2619	480/18670	0.0006439	0.008585	0.006439	CDC25B/CETN2/CDC7/TOPBP1/BTN2A2/CEP135/FBXW7/CNTRL/SKP1/NBN/NDE1/RFWD3/HAUS3/CRADD/CHEK2/PSMB9/CHEK1/EZH2/ADAM17/ATM/CDKN2C/DLGAP5/EGFR/SMARCD3/TPX2/DCTN3/CDK4/TPR/CTDSPL/HAUS2/DBF4/BUB1B/LCMT1/SFI1/HMMR/PSMC2/USP47/DONSON/CDC14A/TPRA1/FGFR1OP/KNTC1/NDC80/MYO16/DCTN2/PLK2/TUBA4A/PSMB6/CENPE/PCM1/CCNB1/PSMC3/TAOK1/CDKN1C/CLASP1/PML/CDC20/AURKB/ZNF16/DYNC1H1/PSMD8/RAD51C/DTL/PSMB5/CSNK1E/ZFP36L2/PSMD10/ALMS1/ERCC2/AKAP9/TAOK3/ATP2B4/SIX3/BABAM1/GTSE1/CDK1/ID2/TMEM14B/CCND2/CDKN1A/WEE1/CEP290/EP300/CEP63/HSPA2/OFD1/KANK2/HMGA2/RAD51B/CENPF/MEPCE/RBL2/FBXO5	93
BP	GO:0006650	glycerophospholipid metabolic process	66/2619	319/18670	0.0006572	0.008743	0.006558	PIGT/GPAA1/PNPLA6/SOCS6/LIPC/PLCG2/PEMT/AGPAT1/PIGK/ABHD6/PLA2G2D/MTMR4/PLA2G15/PGAP2/ATM/MTMR9/SYNJ1/PIKFYVE/AGPAT5/DGKA/PRDX6/PIGA/SOCS1/PIGP/DPM3/HTR2B/OSBPL8/SH3YL1/PLEKHA4/MTMR6/PIK3C2B/PLA2G7/CSNK2B/PCTP/PLD1/PLEKHA1/TAZ/SERINC5/GDE1/PLA2G4C/APOC1/DGKZ/PIK3CB/PIK3R5/EFR3A/PDGFB/MTMR1/PLA1A/PIGH/ACP6/PLBD1/PIGZ/PIK3CD/LPCAT4/INPP5E/PIGC/PGAP3/PIK3C2G/FABP3/STOML2/LPIN1/CPNE6/STARD7/CISH/CHPT1/PIK3CA	66
BP	GO:0009108	coenzyme biosynthetic process	56/2619	261/18670	0.0006588	0.008746	0.00656	GCH1/PDK2/NUPR1/HAAO/QDPR/SNCA/PCBD1/MPC2/NUP160/CBFA2T3/DDIT4/TECR/PNPO/SLC25A1/NUP153/IDO1/PGM1/INSR/ACSL5/TPR/MOCS2/PRKAG1/ENO2/NUP50/COQ6/SLC2A6/GSTZ1/SEC13/RANBP2/PFKFB3/PFKM/IFNG/ACAT1/DLD/IGF1/SCD5/PDK1/NAMPT/NUP210/NADSYN1/NCOR1/COQ9/NUP43/HIF1A/PDHB/NDC1/OGT/PRKAA1/ALDOC/PANK3/EIF6/COQ2/MPC1/NUP98/ADPGK/NUP62	56
BP	GO:1902107	positive regulation of leukocyte differentiation	35/2619	144/18670	0.0006641	0.008799	0.0066	TREM2/BTN2A2/RASGRP1/RIPK2/MALT1/IL15/HLA-G/IL7R/IL4R/LILRB2/PTPRC/BAD/CTNNBIP1/ADA/RUNX3/CD83/SOCS1/LEF1/IL1RL2/TOX/ZAP70/PNP/CD27/IFNG/TRIB1/AXL/TYROBP/CA2/TNFSF4/HMGB1/CYLD/CREB1/ID2/VNN1/XBP1	35
BP	GO:1902992	negative regulation of amyloid precursor protein catabolic process	8/2619	16/18670	0.0006656	0.0088	0.0066	CLU/PRNP/APOE/BIN1/SPON1/ROCK1/IGF1/PIN1	8
BP	GO:0051851	modification by host of symbiont morphology or physiology	22/2619	77/18670	0.0006682	0.008816	0.006612	CCL5/CHD1/APOE/RRP1B/LEF1/FBXL2/PC/ELANE/CCL8/TUSC2/CTDP1/PSMC3/YTHDC2/MBL2/CCNK/HDAC1/TARDBP/PPIB/CTSG/EP300/VAPA/HMGA2	22
BP	GO:0051702	interaction with symbiont	23/2619	82/18670	0.000678	0.008925	0.006694	CCL5/CHD1/APOE/RRP1B/LEF1/FBXL2/PC/GPX1/ELANE/CCL8/TUSC2/CTDP1/PSMC3/YTHDC2/MBL2/CCNK/HDAC1/TARDBP/PPIB/CTSG/EP300/VAPA/HMGA2	23
BP	GO:0009060	aerobic respiration	24/2619	87/18670	0.0006813	0.00895	0.006713	SDHC/CBFA2T3/ME2/NDUFA4/UQCR10/IREB2/BLOC1S1/IDE/COX6C/COX8A/CAT/COX6A1/MDH2/SDHD/SIRT3/DLD/COX5B/HIF1A/PDHB/SUCLG1/NDUFS7/MDH1/FH/UQCRC1	24
BP	GO:0002831	regulation of response to biotic stimulus	34/2619	139/18670	0.000697	0.009137	0.006853	TNFAIP3/AIM2/RNF125/STAT1/BIRC3/MAPK3/RIPK2/TBK1/IL15/MICB/SYT11/LILRA2/PUM2/CARD8/BIRC2/HTRA1/TSPAN6/CRTAM/FAM3A/TRIB1/GPATCH3/MMP12/HMGB1/LY86/TRAF3/OPTN/PPM1B/PRDX2/DDX60/NOD1/SEC14L1/RIOK3/FBXO38/TSPAN32	34
BP	GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	14/2619	40/18670	0.0007063	0.00924	0.006931	PARP3/IL27RA/HLA-F/HLA-G/IL7R/IL4R/PTPRC/THOC1/HFE/RC3H2/CR1/XCL1/TNFSF4/C4BPB	14
BP	GO:0051188	cofactor biosynthetic process	67/2619	326/18670	0.0007246	0.009455	0.007091	GCH1/PDK2/NUPR1/HAAO/QDPR/FECH/SNCA/PCBD1/MPC2/SLC7A11/NUP160/CBFA2T3/DDIT4/TECR/PNPO/SLC25A1/NUP153/IDO1/PGM1/BDH2/IREB2/INSR/ACSL5/TPR/MOCS2/UROD/PRKAG1/ENO2/NUP50/COQ6/SLC2A6/UROS/GSTZ1/SEC13/RANBP2/PFKFB3/PFKM/IFNG/ACAT1/DLD/TSPO/IGF1/SCD5/PDK1/NAMPT/NUP210/NADSYN1/NFE2L1/NCOR1/SOD1/COQ9/NUP43/GGCT/HIF1A/PDHB/NDC1/OGT/PRKAA1/ALDOC/PANK3/CPOX/EIF6/COQ2/MPC1/NUP98/ADPGK/NUP62	67
BP	GO:0010466	negative regulation of peptidase activity	56/2619	262/18670	0.0007257	0.009455	0.007091	MICAL1/BIRC3/PROS1/SNCA/LAMP3/HERPUD1/SLPI/SERPINA3/CFLAR/SPOCK1/SERPINA1/HGF/SERPINA5/NLE1/PTTG1/TIMP2/SERPINE1/CARD8/APLP2/BIRC2/BIRC7/ITIH4/BIN1/SERPINB6/TNFAIP8/NOL3/LEF1/TFPI/USP47/GPX1/CRYAB/ARRB1/CD44/CR1/CD27/AGT/VEGFA/SERPINA4/TIMP4/DHCR24/BIRC5/CST7/NAIP/COL6A3/SPOCK2/IFI16/NGFR/RAF1/TNFSF14/PAK2/TIMP1/CST4/RPS6KA1/SERPINF1/USP14/RNF34	56
BP	GO:0009127	purine nucleoside monophosphate biosynthetic process	42/2619	183/18670	0.0007367	0.009544	0.007158	NUPR1/TREM2/NUP160/CBFA2T3/DDIT4/PID1/IMPDH2/NUP153/ADK/PGM1/PINK1/ADA/INSR/TPR/PRKAG1/ENO2/NUP50/SLC2A6/CYC1/SEC13/AK1/RANBP2/PFKFB3/TAZ/PFKM/IFNG/IGF1/NUP210/COX5B/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/ALDOC/EIF6/STOML2/AMPD3/NUP98/ADPGK/NUP62	42
BP	GO:0009168	purine ribonucleoside monophosphate biosynthetic process	42/2619	183/18670	0.0007367	0.009544	0.007158	NUPR1/TREM2/NUP160/CBFA2T3/DDIT4/PID1/IMPDH2/NUP153/ADK/PGM1/PINK1/ADA/INSR/TPR/PRKAG1/ENO2/NUP50/SLC2A6/CYC1/SEC13/AK1/RANBP2/PFKFB3/TAZ/PFKM/IFNG/IGF1/NUP210/COX5B/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/ALDOC/EIF6/STOML2/AMPD3/NUP98/ADPGK/NUP62	42
BP	GO:0034394	protein localization to cell surface	19/2619	63/18670	0.0007371	0.009544	0.007158	FBLN5/ANGPT1/PIGK/EGF/ASTN2/HFE/WNT11/CD247/TYROBP/PTPRK/EMP2/RANGRF/RAB11B/FCN1/ERBB4/FLNA/BDNF/LRIG2/NEDD4L	19
BP	GO:0031668	cellular response to extracellular stimulus	57/2619	268/18670	0.0007423	0.009592	0.007194	CBS/SFRP1/SIK1/PDK2/PTN/FOLR1/MAP3K5/DAP/MAPK3/GABARAPL1/IL15/FAS/GABARAPL2/PTPRC/SLC38A2/COMT/BAIAP2/PIM1/ATF3/RRAGA/HFE/PENK/PIK3C2B/MED1/PPARG/POSTN/FOLR2/TBL2/AKR1C3/AXL/NAMPT/TRIM24/HNRNPA1/TXN2/P2RX4/ARHGAP35/SOD1/WRN/LPL/AQP2/PRKAA1/IFI16/GSDMD/RRAGD/CDKN1A/XBP1/ASGR1/SESN1/INHBB/ATF4/KANK2/HSPA5/GABARAP/BCL11A/ASNS/CLEC16A/ATP2B1	57
BP	GO:0050673	epithelial cell proliferation	85/2619	434/18670	0.0007657	0.009875	0.007406	TNFAIP3/SIX1/SFRP1/DYSF/NUPR1/PTN/NOTCH1/AR/STAT1/SOX9/CCL5/PRKD2/IGFBP5/FBXW7/PGF/THBS4/SMAD3/CFLAR/HGF/ADAM17/BAD/EGFR/IFT52/APOE/PRKX/RUNX3/IGFBP4/KIT/BCL11B/HTRA1/BMP4/GDF5/CYP7B1/ERBB2/HTR2B/TNMD/MED1/PPARG/GPX1/PPP1R16B/OSR2/KRIT1/PEX2/KLK8/PIK3CB/IGF1/KDR/MYC/ANG/CDKN1C/GHSR/BRCA2/EREG/PDGFB/DEAF1/MMP12/VEGFA/HMGB1/NOD2/MAGED1/LGR5/FERMT1/SCG2/PTPRK/HIF1A/HOXA5/WDR13/HAS2/BCL2L2/NGFR/ID2/STAT5A/TCF7L2/ATF2/XBP1/FABP7/RPS6KA1/FZD7/CEBPB/SMO/SERPINF1/REG3A/TWIST1/VEGFB/NRAS	85
BP	GO:0046474	glycerophospholipid biosynthetic process	48/2619	217/18670	0.0007733	0.009952	0.007465	PIGT/GPAA1/PLCG2/PEMT/AGPAT1/PIGK/PLA2G2D/MTMR4/PGAP2/ATM/MTMR9/SYNJ1/PIKFYVE/AGPAT5/DGKA/PIGA/PIGP/DPM3/HTR2B/SH3YL1/PLEKHA4/MTMR6/PIK3C2B/CSNK2B/PCTP/PLD1/PLEKHA1/TAZ/DGKZ/PIK3CB/PIK3R5/PDGFB/MTMR1/PIGH/ACP6/PIGZ/PIK3CD/LPCAT4/INPP5E/PIGC/PGAP3/PIK3C2G/FABP3/LPIN1/CPNE6/STARD7/CHPT1/PIK3CA	48
BP	GO:0051983	regulation of chromosome segregation	27/2619	103/18670	0.0007786	0.009999	0.0075	SMC6/ECT2/NIPBL/ATM/DLGAP5/PTTG1/PUM2/RACGAP1/MKI67/TPR/DDX11/BUB1B/SPAG5/LCMT1/SMC5/NDC80/CENPE/CCNB1/CDC20/ATRX/AURKB/DYNC1H1/SFPQ/TACC3/PTTG2/CENPF/FBXO5	27
BP	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	26/2619	98/18670	0.0007948	0.01019	0.00764	CLU/HERPUD1/NDUFA13/BCL2A1/NME5/PINK1/CREB3/MAPK7/ING2/NOL3/ARHGEF2/DNAJA1/USP47/GPX1/CD44/HSPB1/TAF9B/TRAP1/MCL1/HIF1A/HDAC1/BCL2L2/NDUFS3/VNN1/TRIM32/XBP1	26
BP	GO:0006525	arginine metabolic process	9/2619	20/18670	0.0008044	0.01028	0.00771	FAH/DDAH1/AGMAT/DDAH2/ASS1/NOS3/CPS1/OAT/ATP2B4	9
BP	GO:0036473	cell death in response to oxidative stress	25/2619	93/18670	0.0008069	0.01028	0.00771	MAP3K5/JAK2/FBXW7/SIGMAR1/SLC7A11/HGF/NME5/PINK1/MAPK7/NOL3/GPX1/HSPB1/PML/PDK1/TRAP1/MELK/ARL6IP5/SFPQ/MCL1/SOD1/HIF1A/VNN1/PYCR1/ATF4/PSAP	25
BP	GO:1901655	cellular response to ketone	25/2619	93/18670	0.0008069	0.01028	0.00771	AKR1B1/SFRP1/AR/CFLAR/DDIT4/EGFR/CDK4/FDX1/EFNA5/PPARG/PTGER4/PTGFR/MAP4K1/ASS1/AKR1C3/ADCY1/PCK2/CASP9/USP8/TNFSF4/AKAP8/PRKAA1/ADCY2/SERPINF1/ATP2B1	25
BP	GO:0090068	positive regulation of cell cycle process	62/2619	298/18670	0.0008114	0.01032	0.007737	CDC25B/SPHK1/CDC7/ECT2/NIPBL/CRADD/BTC/CHEK2/EZH2/ADAM17/ATM/DLGAP5/EGFR/EGF/SMARCD3/RACGAP1/INSR/CDK4/TPR/DDX11/DBF4/NUSAP1/SPAG5/MED1/CD28/SMC5/CDC14A/NDC80/PHIP/PLK2/LRP5/IGF1/INSM1/CCNB1/CRLF3/PML/EREG/ATRX/PDGFB/AURKB/ZNF16/DYNC1H1/RAD51C/DTL/SFPQ/SSTR5/SPAST/GTSE1/CDK1/ID2/CCND2/CDKN1A/EP300/HSPA2/PIWIL2/HMGA2/RAD51B/MEPCE/RBL2/NUP62/DAZL/FBXO5	62
BP	GO:0045582	positive regulation of T cell differentiation	23/2619	83/18670	0.0008152	0.01034	0.007758	BTN2A2/RASGRP1/RIPK2/MALT1/HLA-G/IL7R/IL4R/LILRB2/PTPRC/BAD/ADA/RUNX3/CD83/SOCS1/IL1RL2/ZAP70/PNP/CD27/IFNG/TNFSF4/CYLD/VNN1/XBP1	23
BP	GO:0043401	steroid hormone mediated signaling pathway	42/2619	184/18670	0.0008276	0.01047	0.007854	SFRP1/AR/JAK2/UFSP2/RORA/NCOA3/NCOA6/TADA3/RXRA/BMP4/CYP7B1/DNAJA1/LEF1/MED1/PPARG/KDM3A/PHB/GPER1/ARID1A/YWHAH/LMO3/DAXX/NR1H2/NR3C2/TAF7/BUD31/NR2F1/KAT5/PGRMC2/NCOR1/HDAC1/PADI2/AKAP13/RNF14/FHL2/EP300/CRY1/UBR5/ABHD2/NR5A2/KANK2/NR1D2	42
BP	GO:0002820	negative regulation of adaptive immune response	15/2619	45/18670	0.0008286	0.01047	0.007854	PARP3/IL27RA/HLA-F/HLA-G/IL7R/IL4R/PTPRC/THOC1/TNFRSF14/HFE/RC3H2/CR1/XCL1/TNFSF4/C4BPB	15
BP	GO:0009650	UV protection	7/2619	13/18670	0.0008358	0.0105	0.007874	SCARA3/MFAP4/ERCC1/SDF4/GPX1/CAT/ERCC2	7
BP	GO:0010870	positive regulation of receptor biosynthetic process	7/2619	13/18670	0.0008358	0.0105	0.007874	JAK2/CNPY2/HNRNPK/IFNG/HIF1A/HOXA5/HDAC1	7
BP	GO:0090399	replicative senescence	7/2619	13/18670	0.0008358	0.0105	0.007874	ATR/CHEK2/CHEK1/ATM/SERPINE1/PLA2R1/CDKN1A	7
BP	GO:0042035	regulation of cytokine biosynthetic process	29/2619	114/18670	0.0008583	0.01076	0.00807	IRF1/JAK2/TBK1/PTPRC/IGF2BP3/UBE2J1/NMI/CX3CR1/CD28/ELANE/HSPB1/NFKB1/CD3E/IFNG/TIA1/IL6/GHSR/EGR1/EREG/TYROBP/GLMN/PRKCQ/MAPKAPK2/CEBPG/BCL10/INHBB/TLR8/CCR2/CEBPB	29
BP	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway	10/2619	24/18670	0.0008645	0.01079	0.008092	PRKD2/PRKCB/PTPRC/PRKCH/ADA/CD81/LCK/TRAT1/CCR7/CYLD	10
BP	GO:0051251	positive regulation of lymphocyte activation	68/2619	334/18670	0.0008653	0.01079	0.008092	CD320/CCL5/BTN2A2/RASGRP1/TFRC/IGFBP2/RIPK2/MALT1/IL15/HLA-F/HLA-G/TNIP2/IL7R/IL4R/LILRB2/PTPRC/CD38/GPR183/BAD/HSPH1/CTLA4/NCK2/ADA/RUNX3/TNFRSF14/CD83/HLA-E/SOCS1/IGHM/CD28/IL1RL2/CD40/TOX/ZAP70/MAP3K8/PNP/CD81/PELI1/TRBC1/CD3E/CD27/IFNG/LCK/IGF1/EFNB1/IL6/AXL/TYROBP/XCL1/TNFSF4/HMGB1/CCR7/PRKCQ/NOD2/IGLL5/IGLC1/CYLD/TAC1/IL6R/TNFSF14/VNN1/PAK2/BCL10/CDKN1A/XBP1/CCR2/CD40LG/PIK3CA	68
BP	GO:0045824	negative regulation of innate immune response	18/2619	59/18670	0.0008658	0.01079	0.008092	SLAMF8/TNFAIP3/IRAK3/ADAR/HLA-F/HLA-G/NMI/HLA-E/SAMHD1/CD96/PPARG/FAM3A/PTPN2/CR1/NR1H2/MMP12/IFI16/TYRO3	18
BP	GO:0051169	nuclear transport	70/2619	346/18670	0.0008769	0.01088	0.008162	ZIC1/NFKBIA/ECT2/ANGPT1/HNRNPA2B1/MALT1/SMAD3/NXF3/NUP160/THOC2/BARD1/NUP153/XPO6/KPNA2/DDX39A/NPAP1/THOC1/GSK3B/TPR/PRKAG1/BMP4/NUP50/MED1/SEC13/NMD3/RANBP2/NXF1/RPAIN/CBLB/PPP1R12A/IFNG/BANF1/MBTPS1/AGT/SIX2/SNUPN/TNPO1/PML/SRSF4/NUP210/MMP12/HNRNPA1/RITA1/FERMT1/KPNB1/PPP3CA/CAMK1/NUP43/SNRPD2/NDC1/SETD2/TARDBP/SIX3/AKAP13/GTSE1/YTHDC1/KPNA1/TCF7L2/NCBP2/CDKN1A/EIF6/KPNA3/FLNA/UBR5/SMO/NUP98/HMGA1/GEMIN2/NUP62/NEMF	70
BP	GO:0009314	response to radiation	87/2619	448/18670	0.0008782	0.01088	0.008162	SFRP1/SIK1/CXCL10/PTN/SCARA3/TOPBP1/ECT2/GPR88/DCLRE1C/FECH/MFAP4/ERCC1/NIPBL/RFWD3/CIRBP/ATR/SLC7A11/PTPRC/CHEK2/METAP1/SDF4/CHEK1/ATM/B4GALT2/EGFR/ANGPT2/TNFRSF11A/DYNLRB1/KIT/PENK/USP47/GPX1/GUCA1A/CRYAB/CAT/ARRB1/ELANE/NTRK1/KRT14/POLG/MYC/BRCA2/EGR1/PML/NAMPT/DEAF1/AURKB/CASP9/DTL/RS1/DDB2/RAD1/RUVBL2/NABP2/KAT5/PTPRK/NET1/WRN/AGRP/HIF1A/SMC1A/ERCC2/PRKAA1/IFI16/BABAM1/CREB1/ADIRF/ID2/RAD9A/METAP2/FKBPL/CDKN1A/PDC/N4BP1/CCL7/EP300/TRIM32/COL3A1/TSPYL5/CRY1/KRAS/ATF4/HSPA5/HMGA2/ASNS/TH/RBL2	87
BP	GO:0050671	positive regulation of lymphocyte proliferation	32/2619	130/18670	0.0008785	0.01088	0.008162	CD320/CCL5/TFRC/IGFBP2/RIPK2/IL15/LILRB2/PTPRC/CD38/GPR183/NCK2/ADA/HLA-E/CD28/CD40/ZAP70/PNP/CD81/PELI1/CD3E/IGF1/EFNB1/IL6/XCL1/TNFSF4/HMGB1/PRKCQ/TAC1/IL6R/CDKN1A/CCR2/CD40LG	32
BP	GO:0070646	protein modification by small protein removal	62/2619	299/18670	0.0008864	0.01093	0.008195	TNFAIP3/NFKBIA/AR/BIRC3/USP11/USP46/SMAD3/CCNA2/TNIP2/ATXN7/TNIP1/COPS6/UCHL1/PSMB9/COPS7A/TNIP3/BARD1/USP3/USP24/TADA3/SART3/BIRC2/COPS8/USPL1/PSMC2/USP47/SENP5/USP32/USP34/ADRB2/TAF10/PSMB6/USP27X/TRIM21/ASXL2/TRRAP/PSMC3/MYC/TAF9B/CDC20/USP8/PSMD8/UBB/UCHL3/PSMB5/TRAF3/DDB2/PSMD10/HIF1A/USP9X/USP12/OGT/CYLD/IKBKG/BABAM1/USP48/CDK1/KAT2B/EP300/NEDD8/USP21/USP14	62
BP	GO:0006289	nucleotide-excision repair	28/2619	109/18670	0.0008871	0.01093	0.008195	CETN2/ERCC1/POLD2/COPS6/POLR2J/POLR2I/POLR2L/COPS7A/POLR2E/POLR2F/RPA1/COPS8/MMS19/RNF111/RPA3/POLD4/POLR2C/CCNH/BRCA2/POLR2G/UBB/DDB2/PPIE/ERCC2/MNAT1/EP300/GTF2H3/RFC2	28
BP	GO:0006644	phospholipid metabolic process	84/2619	430/18670	0.0008881	0.01093	0.008195	PIGT/GPAA1/PNPLA6/SOCS6/LIPC/PLCG2/PEMT/AGPAT1/SNCA/PMVK/PIGK/ABHD6/PLA2G2D/MTMR4/PLA2G15/PGAP2/ATM/MTMR9/SYNJ1/PIKFYVE/AGPAT5/DGKA/PRDX6/PIGA/SOCS1/KIT/PIGP/DPM3/HTR2B/OSBPL8/SH3YL1/PLEKHA4/MTMR6/PIK3C2B/PLA2G7/CSNK2B/PCTP/PLD1/PLEKHA1/FGR/TAZ/SERINC5/GDE1/GPX4/DPAGT1/CD81/PLA2G4C/APOC1/DGKZ/PIK3CB/PIK3R5/EFR3A/PDGFB/CD19/MTMR1/DHDDS/PLA1A/PIGH/CCR7/NOD2/WDR91/ACP6/SGMS1/PLCD1/LPL/PLBD1/ISYNA1/PIGZ/PIK3CD/LPCAT4/INPP5E/PIGC/PGAP3/PIK3C2G/FABP3/PTK2B/STOML2/LPIN1/CPNE6/STARD7/CISH/CHPT1/MVK/PIK3CA	84
BP	GO:0010038	response to metal ion	73/2619	364/18670	0.0008889	0.01093	0.008195	CEBPA/LGMN/TNFRSF11B/ECT2/HAAO/IGFBP2/MAPK3/QDPR/ERCC1/SNCA/ALOX5AP/GOT1/SYT11/SDC1/S100A13/BAD/EGFR/PRNP/BSG/NQO1/CDK4/KIT/HFE/SORD/PENK/KCNK3/UROS/ANK3/GUCA1A/GGH/SYT17/CAT/TCIRG1/KRT14/DAXX/CYBRD1/ASS1/CRHBP/CHUK/TSPO/CCNB1/AKR1C3/ADCY1/CPS1/CASP9/CA2/P2RX4/PPP3CA/NFE2L1/SOD1/HIF1A/AQP2/MCOLN1/PRKAA1/ANXA7/CREB1/CDK1/ID2/CPOX/SYT1/MNAT1/RASGRP2/PTK2B/HNRNPD/NPC1/ATF4/SERPINF1/HSPA5/KCNMB2/CPNE6/TH/NEDD4L/NCF1	73
BP	GO:0006360	transcription by RNA polymerase I	19/2619	64/18670	0.0009123	0.01119	0.008394	MAPK3/POLR2L/POLR2E/POLR2F/TAF1D/DDX11/ERBB2/MED1/HEATR1/POLR1B/CCNH/WDR43/ERCC2/MNAT1/POLR1C/FLNA/GTF2H3/BAZ2A/ATF4	19
BP	GO:0032984	protein-containing complex disassembly	67/2619	329/18670	0.0009331	0.01141	0.008555	MICAL1/SETX/IRAK3/STMN2/GAK/GABARAPL1/SH3GL1/GABARAPL2/TMOD1/DDIT4/FGF13/KIF2A/SYNJ1/SMARCD3/UVRAG/GSK3B/INSR/MTRF1/SET/CAPZA1/ARHGEF2/ASPH/MRPL24/TRMT112/KIF18B/MICAL2/ARID1A/MRPL11/ADRB2/VPS16/CHMP2A/MYC/TAOK1/TMOD2/MRPL40/CLASP1/MRPL23/CSNK1A1/SCIN/PBRM1/UBQLN4/FRAT1/SCAF4/MRPS33/PEX14/SPAST/KATNB1/EIF2D/MRPS28/SMARCD2/MCOLN1/MRPS17/CIB1/CHMP1B/MRPS22/MRPS11/MRPL17/MRPL20/LIMA1/MRPL18/MRPS14/NAPA/GABARAP/HMGA1/MRPL4/CLEC16A/FZD2	67
BP	GO:0001890	placenta development	36/2619	152/18670	0.0009334	0.01141	0.008555	PTN/CEBPA/ADAM19/MAPK3/EGFR/BSG/STC1/ADA/BIRC2/MDFI/HTRA1/RXRA/LEF1/MED1/PPARG/ARID1A/RBM15/LDOC1/ANG/CDKN1C/GHSR/RBPJ/PDGFB/PRDM1/TMED2/SOD1/PLCD1/HIF1A/SETD2/BPTF/DAZAP1/GGNBP2/CEBPB/STC2/RTCB/EPOR	36
BP	GO:0007584	response to nutrient	48/2619	219/18670	0.0009537	0.01163	0.008723	SFRP1/PDK2/CXCL10/PTN/FOLR1/STAT1/TNFRSF11B/IGFBP2/PEMT/ERCC1/IL15/BCKDHB/EGFR/BAIAP2/PIM1/NQO1/STC1/ADA/HMGCL/PENK/MED1/PPARG/CAT/POSTN/FOLR2/CD3E/OXCT1/APAF1/ASS1/TSPO/DAD1/AKR1C3/AHCY/TRIM24/P2RX4/NOD2/SOD1/LPL/OGT/TYMS/CREB1/ENSA/XBP1/KANK2/BCL11A/STC2/ATP2B1/ARSB	48
BP	GO:0043367	CD4-positive, alpha-beta T cell differentiation	21/2619	74/18670	0.0009656	0.01175	0.008815	RIPK2/MALT1/RORA/PLA2G2D/SEMA4A/IL4R/GPR183/RUNX3/CD83/SOCS1/LEF1/PTGER4/RC3H2/RELB/IFNG/LY9/IL6/SATB1/TNFSF4/HMGB1/BATF	21
BP	GO:0006094	gluconeogenesis	24/2619	89/18670	0.0009688	0.01177	0.008827	SIK1/PDK2/SDS/GOT1/G6PC3/RBP4/SLC25A1/PGM1/ATF3/ENO2/PC/RANBP2/FAM3A/PTPN2/MDH2/PCK2/OGT/ALDOC/KAT2B/SLC25A11/EP300/MDH1/CRY1/ATF4	24
BP	GO:0071260	cellular response to mechanical stimulus	22/2619	79/18670	0.0009753	0.01183	0.00887	IRF1/SOX9/MAPK3/FAS/GOT1/CRADD/CHEK1/BAD/SLC38A2/EGFR/WNT11/KCNJ2/CD40/PTGER4/NFKB1/AGT/TLR5/CASP8AP2/TNFSF14/BCL10/MYD88/TLR8	22
BP	GO:0010212	response to ionizing radiation	35/2619	147/18670	0.0009867	0.01192	0.008939	SFRP1/CXCL10/TOPBP1/ECT2/DCLRE1C/ERCC1/NIPBL/RFWD3/ATR/PTPRC/CHEK2/ATM/GPX1/CRYAB/KRT14/POLG/MYC/BRCA2/EGR1/PML/NAMPT/RAD1/NABP2/KAT5/NET1/WRN/PRKAA1/IFI16/BABAM1/RAD9A/CDKN1A/CCL7/TSPYL5/HSPA5/HMGA2	35
BP	GO:0061351	neural precursor cell proliferation	35/2619	147/18670	0.0009867	0.01192	0.008939	PTN/NOTCH1/CDH2/NDE1/ASPM/RORA/FGF13/EGF/SMARCD3/ORC3/RACGAP1/CX3CR1/ARHGEF2/LEF1/FZD3/ID4/EML1/PCM1/INSM1/SHCBP1/PTBP2/MELK/VEGFA/DCT/HIF1A/NF2/SIX3/PSMG1/ID2/TMEM14B/FZD6/FABP7/FLNA/SMO/EMX2	35
BP	GO:0032946	positive regulation of mononuclear cell proliferation	32/2619	131/18670	0.001009	0.01216	0.009122	CD320/CCL5/TFRC/IGFBP2/RIPK2/IL15/LILRB2/PTPRC/CD38/GPR183/NCK2/ADA/HLA-E/CD28/CD40/ZAP70/PNP/CD81/PELI1/CD3E/IGF1/EFNB1/IL6/XCL1/TNFSF4/HMGB1/PRKCQ/TAC1/IL6R/CDKN1A/CCR2/CD40LG	32
BP	GO:1903320	regulation of protein modification by small protein conjugation or removal	50/2619	231/18670	0.001014	0.01218	0.009136	TNFAIP3/DYSF/SPHK1/BIRC3/FBXW7/RIPK2/MYCBP2/ANGPT1/MALT1/HERPUD1/TNIP1/FANCI/TRIP12/NMI/PINK1/SART3/BIRC2/CHFR/BIRC7/NDFIP1/UBE2I/DNAJA1/RNF111/PTPN22/TOLLIP/ARRB1/ADRB2/PELI1/DAXX/TRIM21/TSPO/EGR1/CDC20/PIN1/UBB/GLMN/NOD2/AIMP2/PSMD10/OGT/BCL10/N4BP1/TSPYL5/CRY1/UBR5/CDK9/HSPA5/WDR70/DCUN1D1/FBXO5	50
BP	GO:0009156	ribonucleoside monophosphate biosynthetic process	44/2619	197/18670	0.001016	0.01218	0.009136	NUPR1/TREM2/NUP160/CBFA2T3/DDIT4/PID1/IMPDH2/NUP153/ADK/PGM1/PINK1/ADA/INSR/TPR/PRKAG1/ENO2/NUP50/SLC2A6/CYC1/SEC13/AK1/RANBP2/PFKFB3/TAZ/PFKM/IFNG/IGF1/NUP210/COX5B/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/ALDOC/EIF6/PRPS1/PRPS2/STOML2/AMPD3/NUP98/ADPGK/NUP62	44
BP	GO:1901990	regulation of mitotic cell cycle phase transition	86/2619	444/18670	0.001016	0.01218	0.009136	CDC25B/CETN2/CDC7/TOPBP1/BTN2A2/CEP135/CNTRL/SKP1/NBN/NDE1/RFWD3/HAUS3/CRADD/CHEK2/PSMB9/EZH2/ADAM17/ATM/CDKN2C/DLGAP5/EGFR/SMARCD3/TPX2/DCTN3/CDK4/TPR/CTDSPL/HAUS2/BUB1B/LCMT1/SFI1/HMMR/PSMC2/USP47/DONSON/CDC14A/TPRA1/FGFR1OP/KNTC1/NDC80/MYO16/DCTN2/PLK2/TUBA4A/PSMB6/CENPE/PCM1/CCNB1/PSMC3/TAOK1/CDKN1C/CLASP1/PML/CDC20/AURKB/DYNC1H1/PSMD8/RAD51C/DTL/PSMB5/CSNK1E/ZFP36L2/PSMD10/ALMS1/ERCC2/AKAP9/TAOK3/GTSE1/CDK1/ID2/TMEM14B/CCND2/CDKN1A/WEE1/CEP290/EP300/CEP63/HSPA2/OFD1/KANK2/HMGA2/RAD51B/CENPF/MEPCE/RBL2/FBXO5	86
BP	GO:2001020	regulation of response to DNA damage stimulus	47/2619	214/18670	0.001023	0.01222	0.009169	EYA2/PARP3/SMCHD1/ERCC1/CLU/RFWD3/ATR/CHEK2/CHEK1/TRIP12/ATM/EGFR/ZNF365/THOC1/ING2/DDX11/MMS19/HNRNPK/USP47/DEK/SETMAR/CD44/SMYD2/FOXM1/MYC/TAF9B/PML/CASP9/PLA2R1/HMGB1/UBQLN4/MCL1/PSMD10/TIMELESS/SETD2/BABAM1/CEBPG/RAD9A/TRIM32/CRY1/UBR5/CDK9/ACTR2/HMGA2/WDR70/TWIST1/FBXO5	47
BP	GO:0031667	response to nutrient levels	95/2619	499/18670	0.001024	0.01222	0.009169	SFRP1/SIK1/PDK2/CXCL10/PTN/FOLR1/STAT1/MAP3K5/DAP/TNFRSF11B/FIS1/IGFBP2/MAPK3/PEMT/ERCC1/GABARAPL1/IL15/FAS/GABARAPL2/BCKDHB/HSD11B2/SLC38A2/EGFR/COMT/BAIAP2/PIM1/NQO1/STC1/ADA/APOE/ATF3/RRAGA/HFE/SORD/HMGCL/PENK/WNT11/PIK3C2B/MED1/PPARG/BBS4/RMI1/CAT/ADRB2/NTRK1/POSTN/FOLR2/CD3E/OXCT1/APAF1/ACAT1/ASS1/TSPO/DAD1/TBL2/HCRT/GHSR/AKR1C3/PSPH/CPS1/NAMPT/AHCY/PCK2/TRIM24/HNRNPA1/TXN2/P2RX4/NOD2/SOD1/WRN/LPL/OGT/PRKAA1/IFI16/TYMS/CREB1/RRAGD/ENSA/BCL10/CDKN1A/XBP1/SESN1/INHBB/ATF4/KANK2/HSPA5/GABARAP/BCL11A/ASNS/STC2/CLEC16A/ATP2B1/TH/DDIT3/ARSB	95
BP	GO:0050817	coagulation	69/2619	342/18670	0.001026	0.01222	0.009169	VKORC1/MICAL1/IRF1/JAK2/MAPK3/PHF21A/PLCG2/PROS1/SH2B2/PRKAR2A/PRKCB/RAB27A/SLC7A11/SERPINA1/METAP1/SERPINA5/MERTK/SERPINE1/PRKCH/APOE/DGKA/CAPZA1/EHD3/FIBP/TFPI/CD40/F8/ARRB1/F2R/HSPB1/LCK/DGKZ/ITPR2/MAFF/ZFPM2/PIK3CB/COMP/NOS3/GGCX/IL6/PIK3R5/AXL/PDGFB/P2RX4/RAD51C/C4BPB/PRKCQ/CYP4F11/HBB/RCOR1/PRDX2/HDAC1/RAF1/HPS5/KRT1/TYRO3/GNA14/FZD6/FBLN1/COL3A1/SH2B3/FLNA/LCP2/CD40LG/C1GALT1C1/RAD51B/TSPAN32/PIK3CA/CD59	69
BP	GO:0008654	phospholipid biosynthetic process	55/2619	260/18670	0.001038	0.01235	0.00926	PIGT/GPAA1/PLCG2/PEMT/AGPAT1/PMVK/PIGK/PLA2G2D/MTMR4/PGAP2/ATM/MTMR9/SYNJ1/PIKFYVE/AGPAT5/DGKA/PIGA/PIGP/DPM3/HTR2B/SH3YL1/PLEKHA4/MTMR6/PIK3C2B/CSNK2B/PCTP/PLD1/PLEKHA1/TAZ/SERINC5/DPAGT1/DGKZ/PIK3CB/PIK3R5/PDGFB/MTMR1/DHDDS/PIGH/ACP6/SGMS1/ISYNA1/PIGZ/PIK3CD/LPCAT4/INPP5E/PIGC/PGAP3/PIK3C2G/FABP3/LPIN1/CPNE6/STARD7/CHPT1/MVK/PIK3CA	55
BP	GO:0006520	cellular amino acid metabolic process	73/2619	366/18670	0.00104	0.01235	0.009261	CBS/FAH/P4HTM/HPD/IVD/ALDH7A1/BHMT2/HAAO/SDS/QDPR/THNSL2/GAMT/PEMT/BPHL/DDAH1/GOT1/BCKDHB/PCBD1/SLC7A11/PSMB9/PEPD/HSD17B10/DDO/IDO1/COMT/NQO1/AGMAT/NAALAD2/DPYS/SMS/HMGCL/GCAT/ASRGL1/GSTZ1/PSMC2/SLC7A6/CRTAP/SERINC5/MSRA/DDAH2/PSMB6/GATM/ACAT1/HDC/ASS1/MPST/DLD/NOS3/PSMC3/PSPH/CPS1/AHCY/TXN2/PSMD8/OAT/EGLN3/PSMB5/DCT/SRR/AIMP2/PSMD10/ATP2B4/CTPS1/SEPHS1/HNMT/PYCR1/ALDH6A1/ALDH18A1/ATF4/ASNS/OAZ3/TH/PPA2	73
BP	GO:2000273	positive regulation of signaling receptor activity	13/2619	37/18670	0.001043	0.01236	0.00927	FBXW7/NCOA3/ADAM17/EGF/PINK1/HFE/MED1/ADRB2/IFNG/EREG/BUD31/CCR2/NCF1	13
BP	GO:0045807	positive regulation of endocytosis	36/2619	153/18670	0.001059	0.01253	0.009395	IL15RA/TREM2/PLCG2/ANGPT1/SNCA/CLU/IL15/SH3GL1/IL2RG/RAB27A/PTPRC/EGF/MERTK/SERPINE1/APOE/NTF3/HFE/LMAN2/TSPAN1/MAGI2/SELE/HNRNPK/PPARG/ARRB1/IFNG/CD63/IL2RB/CD151/AXL/SLC11A1/VEGFA/PPP3CA/SOD1/MBL2/HIP1R/NEDD4L	36
BP	GO:0001754	eye photoreceptor cell differentiation	15/2619	46/18670	0.001072	0.01266	0.009494	PTN/DIO3/SOX9/AGTPBP1/NTRK2/BBS4/NAGLU/ROM1/PRKCI/PRDM1/VEGFA/CEP290/DSCAM/NRL/TH	15
BP	GO:0032868	response to insulin	57/2619	272/18670	0.001076	0.01268	0.009513	PTPRE/PDK2/STAT1/ENPP1/SH2B2/ATP6V0D1/GOT1/PRKCB/CFLAR/SOS1/PID1/HSD11B2/BAIAP2/GSK3B/INSR/CDK4/SOCS1/IDE/OSBPL8/PPARG/GGH/PTPN2/CAT/TCIRG1/HADH/GRB10/MZB1/PHIP/WDTC1/AGT/PRKCI/RAB13/GHSR/EGR1/SRSF4/PCK2/SORT1/ATP6V0E2/PRKCQ/VAMP2/LPL/AGRP/OGT/PRKAA1/GAL/KAT2B/EIF6/CYFIP1/XBP1/CRY1/INHBB/FABP3/LPIN1/CISH/ATP2B1/PIK3CA/SORBS1	57
BP	GO:0000302	response to reactive oxygen species	50/2619	232/18670	0.00112	0.0131	0.009827	TNFAIP3/GCH1/PDK2/SPHK1/SETX/STAT1/MAP3K5/ECT2/MAPK3/FBLN5/SIGMAR1/CCNA2/CFLAR/HGF/SDC1/EZH2/BAD/EGFR/PINK1/NQO1/ADA/APOE/MAPK7/PLEKHA1/GPX1/CRYAB/CAT/CHUK/ANKZF1/NOS3/IL6/AKR1C3/AXL/TRAP1/CCR7/PTPRK/SOD1/HBB/NET1/PRDX2/PRKAA1/CDK1/MPV17/PYCR1/SESN1/TXNRD2/PTK2B/HNRNPD/PSAP/NCF1	50
BP	GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	72/2619	361/18670	0.001122	0.0131	0.009827	TNFAIP3/C7/HLA-C/PARP3/TNFRSF1B/TFRC/IL27RA/RIPK2/CXCL13/ERCC1/CLU/NBN/MALT1/HLA-F/RORA/HLA-G/MICB/IL7R/HLA-A/RAB27A/SEMA4A/SUSD4/IL4R/PTPRC/RFTN1/CD8A/ADAM17/ADA/THOC1/HLA-B/HLA-E/HFE/IGLV1-44/PRF1/BTN3A3/IGHM/LEF1/CD28/DENND1B/CFI/CD40/GCNT3/TCIRG1/RC3H2/CD81/TRBC1/CR1/CD27/RELB/LY9/IL6/XCL1/SLC11A1/CD19/HLA-DQB1/TNFSF4/HMGB1/C4BPB/PRKCQ/BATF/IGLL5/ULBP2/IGLC1/MBL2/EMP2/IL6R/BCL10/IL13RA2/TLR8/CCR2/FBXO38/CD40LG	72
BP	GO:0010948	negative regulation of cell cycle process	72/2619	361/18670	0.001122	0.0131	0.009827	TOM1L1/CDC7/TOPBP1/BTN2A2/FBXW7/SUZ12/SKP1/NBN/RFWD3/HLA-G/CRADD/CHEK2/PSMB9/MDM1/CHEK1/EZH2/ATM/CDKN2C/PTTG1/CDK4/RRM2/TPR/CTDSPL/BMP4/BUB1B/LCMT1/PSMC2/USP47/DONSON/GPER1/SETMAR/TPRA1/NDC80/MYO16/PLK2/APAF1/PSMB6/CHMP2A/CCNB1/PSMC3/MGA/TAOK1/PML/CDC20/ATRX/AURKB/EED/PSMD8/DTL/PSMB5/RAD1/ZFP36L2/PSMD10/SMC1A/CCNK/TAOK3/BABAM1/RYBP/GTSE1/CDK1/KAT2B/CDKN1A/WEE1/RING1/EP300/CDK9/KANK2/HMGA2/PTTG2/CENPF/RBL2/FBXO5	72
BP	GO:0009247	glycolipid biosynthetic process	19/2619	65/18670	0.001122	0.0131	0.009827	PIGT/GPAA1/GAL3ST4/PIGK/PGAP2/PIGA/PIGP/DPM3/UGCG/ST3GAL2/PIGH/PRKAA1/PIGZ/FA2H/SCCPDH/PIGC/ST8SIA2/PGAP3/B4GALT3	19
BP	GO:0018205	peptidyl-lysine modification	78/2619	397/18670	0.001122	0.0131	0.009827	MTF2/BAZ1A/JARID2/MAPK3/SUZ12/SNCA/WDR61/DNMT1/NUP160/NCOA3/CHEK1/EZH2/GLRX5/ARID4B/NUP153/NAP1L2/TADA3/METTL22/MSL3/SET/TPR/RLF/BLOC1S1/USPL1/UBE2I/NUP50/LEF1/SETD5/ZNF451/EID1/KDM3A/TOLLIP/LIPT1/RANBP2/SENP5/MSL2/SETMAR/JMJD6/ARRB1/SMYD2/AUTS2/TAF10/BRPF1/SIRT3/WDR5B/TRRAP/NAA50/SETD1B/ELP3/BRCA2/EGR1/TAF9B/TAF7/ATRX/NUP210/VCPKMT/EED/RUVBL2/KAT6A/ARID4A/KAT5/NUP43/YEATS2/NDC1/OGT/PRKAA1/SETD2/SUV39H2/CXXC1/KAT2B/ATF2/EP300/PIWIL2/NUP98/MORF4L1/BCL11A/TWIST1/NUP62	78
BP	GO:0042116	macrophage activation	25/2619	95/18670	0.001127	0.01313	0.009847	DYSF/CEBPA/SPHK1/TREM2/CD200/JAK2/SNCA/CLU/RORA/TNIP2/IL4R/PTPRC/ATM/JMJD6/CD93/IFNG/IL6/NAMPT/TYROBP/SLC11A1/MFHAS1/CST7/CRTC3/TLR8/SBNO2	25
BP	GO:0031099	regeneration	44/2619	198/18670	0.001132	0.01317	0.009879	SGCA/DYSF/PTN/NOTCH1/FOLR1/LCP1/JAK2/PGF/CCNA2/CFLAR/PTPRF/NINJ2/HGF/EZH2/EGFR/ANGPT2/PRMT5/CDK4/HFE/CSNK2B/MED1/PPARG/GPX1/CPQ/CD81/POSTN/CERS2/KLK8/TSPO/IGF1/CCNB1/MAP4K4/AXL/EPHA4/PPP3CA/NINJ1/TYMS/CDK1/CDKN1A/ERBB4/FZD7/CEBPB/LPIN1/LRIG2	44
BP	GO:0010810	regulation of cell-substrate adhesion	47/2619	215/18670	0.001134	0.01317	0.009879	GBP1/SFRP1/PTN/NOTCH1/NDNF/JAK2/MACF1/SMAD3/SPOCK1/ARL2/ITGA5/SERPINE1/ANGPT2/NEDD9/GSK3B/CORO2B/LIMCH1/EFNA5/ROCK1/FOXF1/POSTN/CD3E/ARHGEF7/PIK3CB/KDR/RAC2/MAP4K4/CLASP1/MYOC/MMP12/VEGFA/CCR7/AP1AR/FERMT1/SEMA3E/NINJ1/EMID1/SPOCK2/EMP2/HAS2/NF2/CIB1/FBLN1/FLNA/PTK2B/HOXA7/FZD7	47
BP	GO:0010464	regulation of mesenchymal cell proliferation	12/2619	33/18670	0.001142	0.01322	0.009912	SIX1/PTN/STAT1/SOX9/CTNNBIP1/BMP4/WNT11/FOXF1/LRP5/MYC/VEGFA/SMO	12
BP	GO:0032633	interleukin-4 production	12/2619	33/18670	0.001142	0.01322	0.009912	NOTCH1/ITK/CD83/HLA-E/LEF1/CD28/CD3E/RBPJ/TNFSF4/PRKCQ/CEBPB/CD40LG	12
BP	GO:0072091	regulation of stem cell proliferation	20/2619	70/18670	0.001151	0.01329	0.009971	PTN/NOTCH1/ASPM/PTPRC/SMARCD3/LTBP3/CX3CR1/PIM1/N4BP2L2/FZD3/VEGFA/FERMT1/DCT/HIF1A/AGO3/NF2/SIX3/FBLN1/SMO/HMGA2	20
BP	GO:0007569	cell aging	29/2619	116/18670	0.001154	0.0133	0.009974	SMC6/ERCC1/HLA-G/ATR/CHEK2/CHEK1/ATM/SERPINE1/ING2/SMC5/FOXM1/PLK2/BRCA2/PML/NAMPT/PLA2R1/MAP3K3/KAT6A/SOD1/WRN/CDK1/ID2/CDKN1A/KRAS/HMGA1/HMGA2/TWIST1/NUP62/FBXO5	29
BP	GO:0051303	establishment of chromosome localization	21/2619	75/18670	0.001167	0.01342	0.01007	NDE1/ATM/DLGAP5/ACTR3/SPAG5/CDCA8/CHMP6/NDC80/CENPE/CHMP2A/CCNB1/MIS12/DYNC1H1/KPNB1/KATNB1/CHMP1B/CENPC/SPICE1/ACTR2/CENPF/NUP62	21
BP	GO:0032206	positive regulation of telomere maintenance	16/2619	51/18670	0.001183	0.01358	0.01018	MAPK3/ERCC1/HNRNPA2B1/NBN/ATR/TNKS2/ATM/PML/ATRX/HMBOX1/AURKB/HNRNPA1/PRKCQ/RAD50/NABP2/HNRNPD	16
BP	GO:0051897	positive regulation of protein kinase B signaling	40/2619	176/18670	0.001185	0.01358	0.01018	IGFBP5/ANGPT1/BTC/HGF/EGFR/EGF/PINK1/CX3CR1/INSR/KIT/FGF20/ERBB2/OSBPL8/CD28/GPX1/LCK/TRAT1/PIK3CB/FGF18/RAC2/PIK3R5/HBEGF/AKR1C3/MYOC/AXL/EREG/PDGFB/CD19/MFHAS1/MTDH/P2RX4/CALCR/CCR7/PIK3CD/TCF7L2/ERBB4/TSPYL5/FGF5/ARFGEF1/PIK3CA	40
BP	GO:1901342	regulation of vasculature development	82/2619	422/18670	0.001192	0.01364	0.01023	TNFAIP3/SFRP1/CXCL10/PTN/NOTCH1/SPHK1/STAT1/PRKD2/FBXW7/CXCL13/PGF/THBS4/DDAH1/HLA-G/PRKCB/TMEM100/SEMA4A/CFLAR/DNMT1/FOXC1/HGF/ITGAX/ITGA5/CX3CR1/SERPINE1/ANGPT2/KIT/MAPK7/BMP4/HSPB6/ERBB2/JAK1/TNMD/CMA1/PPARG/ROCK1/PPP1R16B/CD40/GPER1/CXCR4/TIE1/HSPB1/KRIT1/CDH5/PLK2/AGT/NOS3/FGF18/S100A1/KDR/IL6/GHSR/EGR1/PML/PDGFB/MTDH/VEGFA/PLXND1/CXCR2/SEMA3E/MAP3K3/HIF1A/HOXA5/EMP2/CIB1/NGFR/IL6R/THBS2/KRT1/FKBPL/ATF2/XBP1/FOXJ2/CXCL8/PTK2B/COL4A2/CCR2/GPR4/SERPINF1/HMGA2/TWIST1/VEGFB	82
BP	GO:0036499	PERK-mediated unfolded protein response	9/2619	21/18670	0.001234	0.01404	0.01053	HERPUD1/NCK2/ATF3/PTPN2/CXCL8/ATF4/HSPA5/ASNS/DDIT3	9
BP	GO:0039531	regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway	9/2619	21/18670	0.001234	0.01404	0.01053	RNF125/BIRC3/PUM2/BIRC2/TSPAN6/GPATCH3/DDX60/SEC14L1/RIOK3	9
BP	GO:0045061	thymic T cell selection	9/2619	21/18670	0.001234	0.01404	0.01053	PTPRC/CD28/PTPN2/ZAP70/CD3E/CD3D/CCR7/JAG2/CD3G	9
BP	GO:0060330	regulation of response to interferon-gamma	10/2619	25/18670	0.001261	0.01425	0.01069	STAT1/JAK2/SOCS1/JAK1/MED1/PPARG/PTPN2/IFNG/NR1H2/TXK	10
BP	GO:0060334	regulation of interferon-gamma-mediated signaling pathway	10/2619	25/18670	0.001261	0.01425	0.01069	STAT1/JAK2/SOCS1/JAK1/MED1/PPARG/PTPN2/IFNG/NR1H2/TXK	10
BP	GO:0072012	glomerulus vasculature development	10/2619	25/18670	0.001261	0.01425	0.01069	NOTCH1/ANGPT1/CFLAR/ANGPT2/PECAM1/BMP4/EGR1/PDGFB/IL6R/GPR4	10
BP	GO:0090025	regulation of monocyte chemotaxis	10/2619	25/18670	0.001261	0.01425	0.01069	SLAMF8/CXCL10/LGMN/CCL5/SERPINE1/CREB3/PLA2G7/NBL1/HMGB1/CCR2	10
BP	GO:0098586	cellular response to virus	17/2619	56/18670	0.001268	0.0143	0.01073	RNF125/BIRC3/ADAR/BAD/PUM2/BIRC2/TSPAN6/PENK/RRP1B/IRF3/MAPK11/CHUK/GPATCH3/MMP12/DDX60/SEC14L1/RIOK3	17
BP	GO:0006754	ATP biosynthetic process	37/2619	160/18670	0.001274	0.01434	0.01076	NUPR1/TREM2/NUP160/CBFA2T3/DDIT4/PID1/NUP153/PGM1/PINK1/INSR/TPR/PRKAG1/ENO2/NUP50/SLC2A6/CYC1/SEC13/RANBP2/PFKFB3/TAZ/PFKM/IFNG/IGF1/NUP210/COX5B/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/ALDOC/EIF6/STOML2/NUP98/ADPGK/NUP62	37
BP	GO:0060047	heart contraction	58/2619	280/18670	0.001306	0.01468	0.01101	ADORA3/GCH1/SCN1B/ATP1B1/SNTA1/JAK2/FXYD1/ATP2A3/SGCG/SRI/KCNQ1/CELF2/KCNK15/SEMA3A/FXYD6/STC1/ADA/BIN1/EHD3/KCNK3/ASPH/GPX1/KCNJ2/MYL3/CXCR4/TAZ/ITPR2/NPR2/RGS4/ATP2B2/AGT/NOS3/S100A1/HBEGF/P2RX4/MYL4/IRX5/CACNB2/KCNJ8/SOD1/KCNN2/GAA/AKAP9/RANGRF/TAC1/ATP2B4/CACNA1D/KCND1/CXADR/CACNA2D3/FLNA/SLC1A1/ATP2B1/TH/CORIN/NEDD4L/VEGFB/PIK3CA	58
BP	GO:0051403	stress-activated MAPK cascade	59/2619	286/18670	0.001322	0.01483	0.01112	TPD52L1/SFRP1/SPHK1/MAP3K5/RASGRP1/MAPK3/RIPK2/SKP1/SLAMF1/FAS/TNIP2/TNIK/HGF/SEMA3A/EGFR/MAP3K11/PINK1/TNFRSF11A/BIRC7/SEMA4C/DNAJA1/PTPN22/PTGER4/MAP4K1/CRYAB/MAP3K8/NFKB1/FOXM1/CD27/DAXX/TRIB1/AGT/MAPK11/CHUK/MYC/TAOK1/MAP4K4/IRAK4/EPHA4/MFHAS1/VEGFA/UBB/HMGB1/CCR7/NOD2/ARL6IP5/MAPKAPK2/MAP3K3/NCOR1/CYLD/IL1RN/TAOK3/NOD1/IKBKG/PHLPP1/PTK2B/FZD7/CD40LG/NCF1	59
BP	GO:0007405	neuroblast proliferation	18/2619	61/18670	0.00133	0.01489	0.01117	PTN/NOTCH1/NDE1/ASPM/FGF13/SMARCD3/RACGAP1/CX3CR1/ARHGEF2/LEF1/FZD3/ID4/EML1/VEGFA/DCT/HIF1A/SIX3/SMO	18
BP	GO:0010508	positive regulation of autophagy	29/2619	117/18670	0.001332	0.01489	0.01117	MAPK3/RIPK2/VPS13C/TBK1/TRIM22/BAD/UVRAG/PINK1/GSK3B/PIM2/ROCK1/ADRB2/IFNG/PLK2/TRIM21/PIK3CB/KDR/TMEM59/MTDH/HMGB1/OPTN/KAT5/HIF1A/TPCN1/PRKAA1/NOD1/IKBKG/SESN1/CLEC16A	29
BP	GO:0006310	DNA recombination	60/2619	292/18670	0.001337	0.01492	0.01119	SMC6/SETX/CDC7/PARP3/SMCHD1/DCLRE1C/TFRC/IL27RA/ERCC1/NBN/NIPBL/RFWD3/KLHDC3/IL7R/RECQL/PTPRC/UBR2/TCF7/CHEK1/ATM/NCOA6/KPNA2/ZNF365/RPA1/THOC1/BCL11B/SAMHD1/MMS19/LEF1/RPA3/CD28/RNF138/SMC5/RMI1/CD40/RPAIN/HMGB3/BRCA2/TNFSF4/HMGB1/UBQLN4/RAD51C/RAD50/BATF/TOP2A/SFPQ/RUVBL2/NABP2/WRN/ERCC2/TSN/TIMELESS/SETD2/C11orf80/TCF3/KPNA1/CD40LG/ACTR2/MORF4L1/RAD51B	60
BP	GO:0045058	T cell selection	15/2619	47/18670	0.001373	0.01527	0.01145	IL15/PTPRC/BCL11B/CD28/PTPN2/ZAP70/CD3E/LY9/CD3D/IL6/CCR7/BATF/JAG2/CYLD/CD3G	15
BP	GO:0050435	amyloid-beta metabolic process	15/2619	47/18670	0.001373	0.01527	0.01145	CLU/PRNP/APOE/BIN1/IDE/GSAP/SPON1/ROCK1/IFNG/IGF1/PSENEN/EPHA4/PIN1/TMED10/APH1A	15
BP	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	23/2619	86/18670	0.001381	0.01532	0.01149	FAM162A/DAP/JAK2/SNCA/SMAD3/FAS/CRADD/BAD/NLRP1/CARD8/CASP4/PPARG/F2R/LCK/APAF1/PML/CASP9/CASP8AP2/MTCH1/EGLN3/NOD1/NGFR/HIP1R	23
BP	GO:0032620	interleukin-17 production	13/2619	38/18670	0.001384	0.01533	0.0115	SPHK1/IL27RA/IL15/RFTN1/PRNP/TUSC2/IFNG/LY9/IL6/TNFSF4/PRKCQ/NOD2/MYD88	13
BP	GO:0006354	DNA-templated transcription, elongation	28/2619	112/18670	0.00139	0.01537	0.01153	TCEA2/HTATSF1/WDR61/POLR2J/POLR2I/POLR2L/EZH2/POLR2E/POLR2F/THOC1/TAF1D/POLR2C/POLR1B/CCNT2/CTDP1/CCNH/ELP3/POLR2G/PBRM1/ELL2/CCNK/ERCC2/SETD2/NCBP2/MNAT1/POLR1C/GTF2H3/CDK9	28
BP	GO:0072525	pyridine-containing compound biosynthetic process	35/2619	150/18670	0.001439	0.01589	0.01192	NUPR1/HAAO/NUP160/CBFA2T3/DDIT4/PNPO/NUP153/IDO1/PGM1/INSR/TPR/PRKAG1/ENO2/NUP50/SLC2A6/SEC13/RANBP2/PFKFB3/PFKM/IFNG/IGF1/NAMPT/NUP210/NADSYN1/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/ALDOC/EIF6/NUP98/ADPGK/NUP62	35
BP	GO:0050679	positive regulation of epithelial cell proliferation	45/2619	206/18670	0.001448	0.01596	0.01197	TNFAIP3/SFRP1/DYSF/PTN/NOTCH1/AR/SOX9/CCL5/PRKD2/PGF/THBS4/CFLAR/ADAM17/BAD/EGFR/HTRA1/BMP4/CYP7B1/ERBB2/HTR2B/MED1/PPP1R16B/OSR2/IGF1/KDR/MYC/ANG/GHSR/PDGFB/MMP12/VEGFA/HMGB1/NOD2/SCG2/HIF1A/HAS2/STAT5A/TCF7L2/XBP1/FZD7/SMO/REG3A/TWIST1/VEGFB/NRAS	45
BP	GO:0009116	nucleoside metabolic process	30/2619	123/18670	0.001462	0.01603	0.01202	NME4/TK2/NME7/GAMT/PEMT/ENTPD4/IMPDH2/NT5C2/NME5/ADK/ADA/APOBEC3C/MACROD1/MOCS2/DPYS/DGUOK/NME3/TYMP/PNP/APOBEC3B/GUK1/AHCY/DNPH1/CTPS1/MPP1/TJP2/NT5E/PRPS1/PRPS2/AMPD3	30
BP	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process	7/2619	14/18670	0.00147	0.01603	0.01202	ATM/PIKFYVE/PIK3C2B/PIK3CB/PIK3CD/PIK3C2G/PIK3CA	7
BP	GO:0050862	positive regulation of T cell receptor signaling pathway	7/2619	14/18670	0.00147	0.01603	0.01202	PRKD2/ADA/CD81/LCK/TRAT1/CCR7/CYLD	7
BP	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade	7/2619	14/18670	0.00147	0.01603	0.01202	PRNP/GSK3B/MAPK7/DYRK2/HOMER3/ATP2B4/FHL2	7
BP	GO:0097202	activation of cysteine-type endopeptidase activity	7/2619	14/18670	0.00147	0.01603	0.01202	LGMN/RIPK2/BAD/ASPH/CYFIP2/CIDEB/IFI16	7
BP	GO:0106057	negative regulation of calcineurin-mediated signaling	7/2619	14/18670	0.00147	0.01603	0.01202	PRNP/GSK3B/MAPK7/DYRK2/HOMER3/ATP2B4/FHL2	7
BP	GO:0050821	protein stabilization	40/2619	178/18670	0.001485	0.01616	0.01212	ATP1B1/IFT46/FBXW7/CLU/SMAD3/TNIP2/CHEK2/PEX19/ATF7IP/MTMR9/PFN2/PINK1/PIM1/TSPAN1/PIM2/PHB/CRYAB/CRTAP/PRKRA/NAA16/USP27X/IGF1/CCNH/SEC16A/TAF9B/TYROBP/EPHA4/PIN1/NLK/USP9X/PPIB/CREB1/GTSE1/HIP1R/FKBPL/CDKN1A/EP300/FLNA/SMO/SEL1L	40
BP	GO:0045839	negative regulation of mitotic nuclear division	16/2619	52/18670	0.001489	0.01619	0.01214	TOM1L1/CHEK1/ATM/PTTG1/TPR/BMP4/BUB1B/LCMT1/NDC80/CCNB1/CDC20/ATRX/AURKB/PTTG2/CENPF/FBXO5	16
BP	GO:0010975	regulation of neuron projection development	94/2619	499/18670	0.001526	0.01654	0.01241	SFRP1/PTN/SCN1B/SETX/NDNF/CDH2/UST/STMN2/GAK/SEMA4D/MYCBP2/MACF1/TNIK/SEMA4A/CFLAR/SPOCK1/PTPRF/CD38/HGF/SS18L1/SEMA3A/EZH2/FGF13/TUBB2B/ITSN2/BAIAP2/ASAP1/ZNF365/CHN1/NTRK2/APOE/GSK3B/SEMA4C/EFNA5/TMEM30A/MAGI2/DGUOK/TRAK1/PMP22/PARP6/CXCR4/SIPA1L1/SYT17/NTRK1/YWHAH/CERS2/PLK2/CHRNA3/AGT/KLK8/SEMA3F/PRKCI/VAMP7/MAP4K4/RND2/TLX2/CDC20/ITM2C/EPHA4/VEGFA/PLXND1/NR2F1/ARHGAP35/TENM3/SEMA3E/PPP3CA/CAMK1/KATNB1/CTTN/CIB1/GOLGA4/NGFR/TRPV2/CDKL5/PLXNA1/SYT1/CYFIP1/EP300/CAPRIN2/PTK2B/STYXL1/DSCAM/FBXO38/C21orf91/SERPINF1/CAMK2B/ACTR2/HSPA5/CPNE6/BCL11A/BDNF/LRIG2/ARSB/NEDD4L	94
BP	GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	34/2619	145/18670	0.001527	0.01654	0.01241	TNFAIP3/HLA-C/PARP3/TNFRSF1B/TFRC/IL27RA/RIPK2/MALT1/HLA-F/HLA-G/IL7R/HLA-A/IL4R/PTPRC/ADA/THOC1/HLA-B/HLA-E/HFE/CD28/CD40/RC3H2/CD81/CR1/IL6/XCL1/SLC11A1/TNFSF4/HMGB1/C4BPB/PRKCQ/IL6R/CCR2/FBXO38	34
BP	GO:0019722	calcium-mediated signaling	47/2619	218/18670	0.001536	0.01661	0.01246	GBP1/PDK2/SPHK1/ATP1B1/TREM2/FIS1/PLCG2/SRI/TMEM100/CAMTA1/PTPRC/EGFR/PRNP/MCTP1/CX3CR1/ADA/GSK3B/MAPK7/CCR5/DYRK2/HTR2B/SELE/CXCR4/PTGFR/ZAP70/CD3E/TRAT1/IGF1/KDR/P2RX4/PLCE1/CCR7/HOMER3/CXCR2/PPP3CA/LAT/MCOLN1/PRKAA1/ATP2B4/CIB1/FHL2/CXCL8/PTK2B/CCR2/NR5A2/CALML4/CXCR6	47
BP	GO:0032660	regulation of interleukin-17 production	12/2619	34/18670	0.001543	0.01665	0.01249	SPHK1/IL27RA/IL15/PRNP/TUSC2/IFNG/LY9/IL6/TNFSF4/PRKCQ/NOD2/MYD88	12
BP	GO:0007044	cell-substrate junction assembly	25/2619	97/18670	0.00155	0.0167	0.01253	SFRP1/TRIP6/MACF1/SMAD3/ITGA5/CORO2B/LIMCH1/EFNA5/ROCK1/LAMA5/FERMT2/KRT14/ARHGEF7/KDR/MAP4K4/CLASP1/CD151/MYOC/VEGFA/TNS1/PTPRK/CTTN/ACTN1/PTK2B/SORBS1	25
BP	GO:0075733	intracellular transport of virus	17/2619	57/18670	0.001575	0.01694	0.0127	VPS37C/NUP160/NUP153/KPNA2/TPR/NUP50/SEC13/RANBP2/NUP210/UBB/KPNB1/NUP43/NDC1/KPNA1/KPNA3/NUP98/NUP62	17
BP	GO:0032922	circadian regulation of gene expression	18/2619	62/18670	0.001633	0.01753	0.01315	KDM5A/MYCBP2/RORA/KDM2A/PRMT5/RELB/EGR1/PML/NAMPT/TOP1/MAGED1/CSNK1E/OGT/HDAC1/NGFR/ID2/CRY1/ATF4	18
BP	GO:0048771	tissue remodeling	40/2619	179/18670	0.001658	0.01778	0.01333	TNFAIP3/SFRP1/PTN/TNFRSF11B/TFRC/IGFBP5/THBS4/IL15/CD38/FOXC1/PTH1R/EGFR/LTBP3/MERTK/TNFRSF11A/GDF5/NOL3/ROCK1/TCIRG1/S1PR1/F2R/ADRB2/AGT/LRP5/NOS3/RAC2/IL6/RBPJ/AXL/SUCO/CA2/HMGB1/LIPA/PPP3CA/SNX10/HIF1A/TIMP1/NCDN/PTK2B/CCR2	40
BP	GO:0014013	regulation of gliogenesis	30/2619	124/18670	0.001675	0.01793	0.01344	PTN/NOTCH1/TREM2/CDH2/TNFRSF1B/GPR183/EZH2/TNFRSF21/CX3CR1/ZNF365/PRKCH/PRMT5/BIN1/PPARG/CXCR4/ID4/CERS2/PRKCI/TSPO/IL6/EPHA4/P2RX4/HDAC1/NF2/CREB1/CDK1/OLIG2/ID2/CCR2/TENM4	30
BP	GO:1902751	positive regulation of cell cycle G2/M phase transition	11/2619	30/18670	0.001687	0.01802	0.01352	CDC25B/CDC7/SMARCD3/CDK4/CCNB1/RAD51C/DTL/CDK1/HSPA2/RAD51B/FBXO5	11
BP	GO:0051302	regulation of cell division	38/2619	168/18670	0.001696	0.01809	0.01357	CDC25B/PTN/CETN2/ECT2/PGF/THBS4/ASPM/BTC/NCOA3/NAP1L2/UVRAG/RACGAP1/HTR2B/ORC6/BBS4/CDC14A/CAT/KIF18B/PRC1/PLK2/MYC/BRCA2/EREG/PDGFB/AURKB/ZNF16/VEGFA/PIN1/SSTR5/SPAST/YBX1/SETD2/CIB1/KIF20A/FGF5/RBL2/NUP62/VEGFB	38
BP	GO:0006302	double-strand break repair	52/2619	248/18670	0.001711	0.01822	0.01367	SETX/CDC7/PARP3/SMCHD1/DCLRE1C/ERCC1/NBN/NIPBL/RFWD3/RECQL/KDM2A/CHEK2/CHEK1/TRIP12/ATM/BARD1/DNA2/UVRAG/ZNF365/RPA1/DDX11/SAMHD1/MMS19/RPA3/RNF138/SMC5/RMI1/DEK/SETMAR/FOXM1/BRCA2/PML/UBQLN4/RAD51C/RAD50/SFPQ/TDP1/NABP2/KAT5/WRN/DDX1/TIMELESS/SETD2/CIB1/BABAM1/UBR5/ACTR2/MORF4L1/HMGA2/RAD51B/WDR70/TWIST1	52
BP	GO:0002224	toll-like receptor signaling pathway	34/2619	146/18670	0.001728	0.01837	0.01377	TNFAIP3/NFKBIA/IRAK3/LGMN/IRF1/BIRC3/RIPK2/COLEC12/TBK1/TRIL/TNIP2/TNIP1/RFTN1/LILRA2/TNIP3/BIRC2/IRF3/PTPN22/PELI1/CHUK/S100A1/TLR5/IRAK4/MFHAS1/UBB/HMGB1/TRAF3/MAPKAPK2/GRAMD4/IKBKG/TYRO3/BCL10/MYD88/TLR8	34
BP	GO:0006874	cellular calcium ion homeostasis	87/2619	458/18670	0.00174	0.01837	0.01378	CXCL9/RMDN3/CXCL10/ATP1B1/JAK2/CCL5/FIS1/ATP2A3/PLCG2/CXCL13/SNCA/SRI/ATP13A3/SMAD3/HERPUD1/CXCL11/GOT1/EPHX2/PRKCB/PTPRC/CD38/PTH1R/ATP2C1/PRNP/CX3CR1/STC1/APOE/CCR5/NOL3/HTR2B/GNG3/KCNK3/CD40/PTGER4/GPER1/CXCR4/PTGFR/TCIRG1/S1PR1/ELANE/F2R/TMCO1/CCL8/CDH5/LCK/ITPR2/MCOLN3/ATP2B2/AGT/PIK3CB/HCRT/HCRTR2/PML/FAM155A/XCL1/CD19/P2RX4/HMGB1/CALCR/PLCE1/CCR7/CXCR2/MICU1/CCL13/CACNB2/NMB/LIME1/CALB2/TPCN1/MCOLN1/LPAR2/ANXA7/TAC1/ATP2B4/CACNA1D/CCL7/MS4A1/PTK2B/CCR2/ATF4/STOML2/GPR4/LETM1/STC2/ATP2B1/DDIT3/CXCR6	87
BP	GO:0070233	negative regulation of T cell apoptotic process	8/2619	18/18670	0.001743	0.01837	0.01378	CCL5/IL7R/IDO1/ADA/BMP4/CD27/PRKCQ/HIF1A	8
BP	GO:0072574	hepatocyte proliferation	8/2619	18/18670	0.001743	0.01837	0.01378	TNFAIP3/PTN/FBXW7/CFLAR/MED1/XBP1/RPS6KA1/CEBPB	8
BP	GO:0072575	epithelial cell proliferation involved in liver morphogenesis	8/2619	18/18670	0.001743	0.01837	0.01378	TNFAIP3/PTN/FBXW7/CFLAR/MED1/XBP1/RPS6KA1/CEBPB	8
BP	GO:0090026	positive regulation of monocyte chemotaxis	8/2619	18/18670	0.001743	0.01837	0.01378	CXCL10/LGMN/CCL5/SERPINE1/CREB3/PLA2G7/HMGB1/CCR2	8
BP	GO:0006913	nucleocytoplasmic transport	68/2619	343/18670	0.001774	0.01867	0.014	ZIC1/NFKBIA/ECT2/ANGPT1/HNRNPA2B1/MALT1/SMAD3/NXF3/NUP160/THOC2/BARD1/NUP153/XPO6/KPNA2/DDX39A/NPAP1/THOC1/GSK3B/TPR/PRKAG1/BMP4/NUP50/MED1/SEC13/NMD3/RANBP2/NXF1/RPAIN/CBLB/PPP1R12A/IFNG/MBTPS1/AGT/SIX2/SNUPN/TNPO1/PML/SRSF4/NUP210/MMP12/HNRNPA1/RITA1/FERMT1/KPNB1/PPP3CA/CAMK1/NUP43/SNRPD2/NDC1/SETD2/TARDBP/SIX3/AKAP13/GTSE1/YTHDC1/KPNA1/TCF7L2/NCBP2/CDKN1A/EIF6/KPNA3/FLNA/UBR5/SMO/NUP98/GEMIN2/NUP62/NEMF	68
BP	GO:0050926	regulation of positive chemotaxis	10/2619	26/18670	0.001794	0.01882	0.01411	PGF/SMAD3/ANGPT2/NTF3/S1PR1/KDR/VEGFA/SCG2/CXCL8/VEGFB	10
BP	GO:1904353	regulation of telomere capping	10/2619	26/18670	0.001794	0.01882	0.01411	MAPK3/ERCC1/NBN/TNKS2/ATM/AURKB/PRKCQ/RAD50/NABP2/HNRNPD	10
BP	GO:0031669	cellular response to nutrient levels	50/2619	237/18670	0.001811	0.01889	0.01417	SFRP1/SIK1/PDK2/PTN/FOLR1/MAP3K5/DAP/MAPK3/GABARAPL1/IL15/FAS/GABARAPL2/SLC38A2/COMT/BAIAP2/PIM1/ATF3/RRAGA/HFE/PENK/PIK3C2B/MED1/PPARG/POSTN/FOLR2/TBL2/AKR1C3/NAMPT/TRIM24/HNRNPA1/TXN2/P2RX4/SOD1/WRN/LPL/PRKAA1/IFI16/RRAGD/CDKN1A/XBP1/SESN1/INHBB/ATF4/KANK2/HSPA5/GABARAP/BCL11A/ASNS/CLEC16A/ATP2B1	50
BP	GO:0019048	modulation by virus of host morphology or physiology	13/2619	39/18670	0.001813	0.01889	0.01417	SMAD3/BAD/KPNA2/INSR/RRAGA/RXRA/CCL8/KPNB1/CCNK/TYMS/KPNA1/KPNA3/VAPA	13
BP	GO:0048713	regulation of oligodendrocyte differentiation	13/2619	39/18670	0.001813	0.01889	0.01417	PTN/NOTCH1/TNFRSF1B/TNFRSF21/ZNF365/PRMT5/PPARG/CXCR4/ID4/HDAC1/OLIG2/ID2/TENM4	13
BP	GO:2000648	positive regulation of stem cell proliferation	13/2619	39/18670	0.001813	0.01889	0.01417	NOTCH1/ASPM/PTPRC/SMARCD3/LTBP3/CX3CR1/N4BP2L2/FZD3/VEGFA/DCT/HIF1A/SMO/HMGA2	13
BP	GO:0055074	calcium ion homeostasis	89/2619	471/18670	0.001823	0.01889	0.01417	CXCL9/RMDN3/CXCL10/ATP1B1/JAK2/CCL5/FIS1/ATP2A3/PLCG2/CXCL13/SNCA/SRI/ATP13A3/SMAD3/HERPUD1/CXCL11/GOT1/EPHX2/PRKCB/PTPRC/CD38/PTH1R/ATP2C1/PRNP/CX3CR1/STC1/APOE/CCR5/NOL3/HTR2B/GNG3/KCNK3/CD40/PTGER4/GPER1/CXCR4/PTGFR/TCIRG1/S1PR1/ELANE/F2R/TMCO1/CCL8/CDH5/LCK/ITPR2/MCOLN3/ATP2B2/AGT/PIK3CB/HCRT/HCRTR2/PML/FAM155A/XCL1/TRIM24/CD19/P2RX4/HMGB1/CALCR/PLCE1/CCR7/CXCR2/MICU1/CCL13/CACNB2/SNX10/NMB/LIME1/CALB2/TPCN1/MCOLN1/LPAR2/ANXA7/TAC1/ATP2B4/CACNA1D/CCL7/MS4A1/PTK2B/CCR2/ATF4/STOML2/GPR4/LETM1/STC2/ATP2B1/DDIT3/CXCR6	89
BP	GO:0002052	positive regulation of neuroblast proliferation	9/2619	22/18670	0.00183	0.01889	0.01417	NOTCH1/ASPM/SMARCD3/CX3CR1/FZD3/VEGFA/DCT/HIF1A/SMO	9
BP	GO:0010869	regulation of receptor biosynthetic process	9/2619	22/18670	0.00183	0.01889	0.01417	JAK2/SEC24A/CNPY2/HNRNPK/PPARG/IFNG/HIF1A/HOXA5/HDAC1	9
BP	GO:0032727	positive regulation of interferon-alpha production	9/2619	22/18670	0.00183	0.01889	0.01417	STAT1/RIPK2/TBK1/IRF3/CHUK/MMP12/HMGB1/SETD2/TLR8	9
BP	GO:0001558	regulation of cell growth	80/2619	416/18670	0.001835	0.01889	0.01417	KAZALD1/SFRP1/SPHK1/ENPP1/IGFBP5/SEMA4D/FBLN5/MACF1/SMAD3/SEMA4A/NDUFA13/SPOCK1/CD38/SEMA3A/ADAM17/FGF13/CDKN2C/EGFR/ITSN2/APOE/GSK3B/IGFBP4/SEMA4C/ERBB2/EFNA5/WNT11/LEF1/USP47/PPARG/PHB/CXCR4/CRYAB/SYT17/FGFR1OP/RGS4/AGT/SEMA3F/CTDP1/IGF1/CRLF3/RND2/HBEGF/TAF9B/PML/VEGFA/PIN1/IL17RB/PLCE1/PRKCQ/LAMTOR2/SEMA3E/NET1/LTBP4/PSMD10/DNPH1/CTTN/CIB1/GOLGA4/GDF9/TRPV2/TNK1/NDUFS3/GAL/CDKL5/SYT1/CDKN1A/CYFIP1/TRIM32/CAPRIN2/RASGRP2/RPS6KA1/PTK2B/DSCAM/CPNE6/BCL11A/BDNF/CISH/CHPT1/TMEM97/NEDD4L	80
BP	GO:0072593	reactive oxygen species metabolic process	58/2619	284/18670	0.001844	0.01889	0.01417	GCH1/GCHFR/JAK2/SLC18A2/FBLN5/SNCA/CLU/SMAD3/DDAH1/RORA/EPHX2/RAB27A/NDUFA13/NDUFS4/CFLAR/DDIT4/PID1/EGFR/PINK1/CX3CR1/NQO1/INSR/BIRC2/GPX3/PRDX6/PXDN/GPX1/CRYAB/CAT/TUSC2/FOXM1/DDAH2/IFNG/SIRT3/AGT/ASS1/TSPO/NOS3/RAC2/AKR1C3/CPS1/TYROBP/PDGFB/TRAP1/P2RX4/PLA2R1/SOD1/HBB/HIF1A/PRDX2/ATP2B4/NDUFS3/MPV17/CDKN1A/EIF6/SESN1/PTK2B/NCF1	58
BP	GO:0030282	bone mineralization	28/2619	114/18670	0.001848	0.01889	0.01417	PTN/NELL1/SOX9/ENPP1/MGP/ANKH/SMAD3/ATRAID/PTH1R/LTBP3/BMP4/WNT11/FGR/S1PR1/OSR2/ADRB2/IGF1/COMP/MMP13/SNX10/HIF1A/ERCC2/ZBTB40/PTK2B/ATP2B1/TWIST1/SRGN/SBNO2	28
BP	GO:0006558	L-phenylalanine metabolic process	6/2619	11/18670	0.001856	0.01889	0.01417	FAH/HPD/QDPR/PCBD1/ASRGL1/GSTZ1	6
BP	GO:0006559	L-phenylalanine catabolic process	6/2619	11/18670	0.001856	0.01889	0.01417	FAH/HPD/QDPR/PCBD1/ASRGL1/GSTZ1	6
BP	GO:0019371	cyclooxygenase pathway	6/2619	11/18670	0.001856	0.01889	0.01417	HPGDS/PTGS1/TBXAS1/AKR1C3/PTGDS/CBR1	6
BP	GO:0070106	interleukin-27-mediated signaling pathway	6/2619	11/18670	0.001856	0.01889	0.01417	STAT1/JAK2/CRLF1/IL27RA/TYK2/JAK1	6
BP	GO:1902221	erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process	6/2619	11/18670	0.001856	0.01889	0.01417	FAH/HPD/QDPR/PCBD1/ASRGL1/GSTZ1	6
BP	GO:1902222	erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process	6/2619	11/18670	0.001856	0.01889	0.01417	FAH/HPD/QDPR/PCBD1/ASRGL1/GSTZ1	6
BP	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	6/2619	11/18670	0.001856	0.01889	0.01417	ATF3/ATF6/CEBPB/ATF4/HSPA5/DDIT3	6
BP	GO:0003015	heart process	59/2619	290/18670	0.001858	0.01889	0.01417	ADORA3/GCH1/SCN1B/ATP1B1/SNTA1/JAK2/FXYD1/ATP2A3/SGCG/SRI/KCNQ1/CELF2/KCNK15/SEMA3A/FXYD6/STC1/ADA/BIN1/EHD3/KCNK3/ASPH/GPX1/KCNJ2/MYL3/CXCR4/TAZ/ITPR2/NPR2/RGS4/ATP2B2/AGT/NOS3/S100A1/HBEGF/P2RX4/MYL4/IRX5/CACNB2/KCNJ8/SOD1/KCNN2/GAA/AKAP9/RANGRF/TAC1/ATP2B4/CACNA1D/AKAP13/KCND1/CXADR/CACNA2D3/FLNA/SLC1A1/ATP2B1/TH/CORIN/NEDD4L/VEGFB/PIK3CA	59
BP	GO:0006476	protein deacetylation	24/2619	93/18670	0.001868	0.01896	0.01422	BEX4/KDM5A/PRKD2/NIPBL/TADA3/PINK1/MSL3/ING2/ZNHIT1/PHB/NEK3/IFNG/SIRT3/VEGFA/SFPQ/RCOR1/AKAP8/HDAC1/PRKAA1/SAP30/EP300/BAZ2A/MORF4L1/SIRT7	24
BP	GO:0048660	regulation of smooth muscle cell proliferation	38/2619	169/18670	0.001898	0.0192	0.0144	TNFAIP3/AKR1B1/STAT1/MAP3K5/JAK2/CCL5/IGFBP5/IL15/DNMT1/PDE1A/ABCC4/EGFR/COMT/CTNNBIP1/BMP4/HPGD/PPARG/GPER1/S1PR1/ELANE/NDRG2/IFNG/TRIB1/AGT/IGF1/ANG/IL6/HBEGF/IRAK4/NAMPT/EREG/PDGFB/IL6R/ID2/TCF7L2/CDKN1A/MNAT1/FOXJ2	38
BP	GO:0051100	negative regulation of binding	38/2619	169/18670	0.001898	0.0192	0.0144	NFKBIA/JAK2/FBXW7/MAPK3/SRI/SLPI/LRPAP1/BTAF1/PTPRF/PEX19/TDG/CTNNBIP1/GSK3B/MDFI/HFE/DDX11/LEF1/PIM2/ROCK1/GZMA/ADRB2/ID4/PDGFB/AURKB/PIN1/CSNK1E/RUVBL2/PPP3CA/PEX14/CAMK1/IFI16/ID2/ID3/SMO/HSPA5/HMGA2/MEPCE/DDIT3	38
BP	GO:0030278	regulation of ossification	44/2619	203/18670	0.001907	0.01927	0.01445	SFRP1/PTN/NOTCH1/CEBPA/NELL1/SOX9/ENPP1/IGFBP5/SEMA4D/MAPK3/MGP/NIPBL/ANKH/SMAD3/ATRAID/DHRS3/HGF/LTBP3/CTNNBIP1/BMP4/PTGER4/TCIRG1/S1PR1/OSR2/ADRB2/LRP5/IGF1/COMP/SIX2/IL6/RBPJ/SUCO/HIF1A/TAC1/IL6R/ID2/ID3/PTK2B/CEBPB/ATP2B1/GDPD2/TWIST1/SRGN/FBXO5	44
BP	GO:1904035	regulation of epithelial cell apoptotic process	23/2619	88/18670	0.001921	0.01938	0.01453	TNFAIP3/NUPR1/NDNF/JAK2/ANGPT1/HLA-G/TNIP2/CFLAR/BAD/SERPINE1/MAPK7/CD40/GPER1/KRIT1/TIA1/PRKCI/KDR/IL6/AKR1C3/SORT1/SCG2/TCF7L2/CD40LG	23
BP	GO:0019359	nicotinamide nucleotide biosynthetic process	34/2619	147/18670	0.001951	0.01961	0.01471	NUPR1/HAAO/NUP160/CBFA2T3/DDIT4/NUP153/IDO1/PGM1/INSR/TPR/PRKAG1/ENO2/NUP50/SLC2A6/SEC13/RANBP2/PFKFB3/PFKM/IFNG/IGF1/NAMPT/NUP210/NADSYN1/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/ALDOC/EIF6/NUP98/ADPGK/NUP62	34
BP	GO:0019363	pyridine nucleotide biosynthetic process	34/2619	147/18670	0.001951	0.01961	0.01471	NUPR1/HAAO/NUP160/CBFA2T3/DDIT4/NUP153/IDO1/PGM1/INSR/TPR/PRKAG1/ENO2/NUP50/SLC2A6/SEC13/RANBP2/PFKFB3/PFKM/IFNG/IGF1/NAMPT/NUP210/NADSYN1/NCOR1/NUP43/HIF1A/NDC1/OGT/PRKAA1/ALDOC/EIF6/NUP98/ADPGK/NUP62	34
BP	GO:0042982	amyloid precursor protein metabolic process	18/2619	63/18670	0.001991	0.01992	0.01494	CLU/PRNP/NECAB3/APOE/BIN1/GSAP/SPON1/ROCK1/IFNG/IGF1/PSENEN/ITM2C/EPHA4/PIN1/DHCR24/TMED10/APH1A/TMCC2	18
BP	GO:0045815	positive regulation of gene expression, epigenetic	18/2619	63/18670	0.001991	0.01992	0.01494	POLR2L/CHEK1/POLR2E/POLR2F/SF3B1/ATAD2B/TAF1D/DEK/POLR1B/ARID1A/SMARCA5/PADI2/DDX21/KAT2B/ATAD2/EP300/POLR1C/HMGA1	18
BP	GO:0046530	photoreceptor cell differentiation	18/2619	63/18670	0.001991	0.01992	0.01494	PTN/NOTCH1/DIO3/SOX9/ARL3/AGTPBP1/NTRK2/BBS4/NAGLU/ROM1/PRKCI/PRDM1/VEGFA/IFT140/CEP290/DSCAM/NRL/TH	18
BP	GO:0031100	animal organ regeneration	20/2619	73/18670	0.002015	0.02006	0.01505	NOTCH1/LCP1/PGF/CCNA2/HGF/EZH2/EGFR/ANGPT2/PRMT5/CDK4/HFE/CSNK2B/MED1/PPARG/AXL/TYMS/CDK1/CDKN1A/CEBPB/LPIN1	20
BP	GO:0044766	multi-organism transport	20/2619	73/18670	0.002015	0.02006	0.01505	VPS37C/NUP160/THOC2/NUP153/KPNA2/THOC1/TPR/RAB40B/NUP50/SEC13/RANBP2/NUP210/UBB/KPNB1/NUP43/NDC1/KPNA1/KPNA3/NUP98/NUP62	20
BP	GO:1902579	multi-organism localization	20/2619	73/18670	0.002015	0.02006	0.01505	VPS37C/NUP160/THOC2/NUP153/KPNA2/THOC1/TPR/RAB40B/NUP50/SEC13/RANBP2/NUP210/UBB/KPNB1/NUP43/NDC1/KPNA1/KPNA3/NUP98/NUP62	20
BP	GO:0051896	regulation of protein kinase B signaling	51/2619	244/18670	0.00202	0.02008	0.01506	BTN2A2/IGFBP5/ANGPT1/HLA-G/BTC/HGF/EGFR/EGF/PINK1/CX3CR1/NTRK2/INSR/KIT/FGF20/ERBB2/OSBPL8/MAGI2/RCN3/CD28/PLEKHA1/GPX1/GPER1/LCK/TRAT1/PIK3CB/FGF18/RAC2/PIK3R5/HBEGF/AKR1C3/MYOC/AXL/EREG/PDGFB/CD19/MFHAS1/MTDH/P2RX4/CALCR/CCR7/CIB1/PIK3CD/TCF7L2/ERBB4/TSPYL5/SH2B3/PHLPP1/FGF5/ARFGEF1/DDIT3/PIK3CA	51
BP	GO:0090311	regulation of protein deacetylation	14/2619	44/18670	0.002028	0.02013	0.0151	BEX4/KDM5A/PRKD2/NIPBL/TADA3/PINK1/ING2/ZNHIT1/NEK3/IFNG/VEGFA/AKAP8/PRKAA1/EP300	14
BP	GO:0001893	maternal placenta development	12/2619	35/18670	0.002052	0.0203	0.01523	PTN/MAPK3/BSG/STC1/RXRA/LDOC1/GHSR/PRDM1/TMED2/DAZAP1/STC2/EPOR	12
BP	GO:1902991	regulation of amyloid precursor protein catabolic process	12/2619	35/18670	0.002052	0.0203	0.01523	CLU/PRNP/APOE/BIN1/GSAP/SPON1/ROCK1/IFNG/IGF1/EPHA4/PIN1/TMED10	12
BP	GO:0031098	stress-activated protein kinase signaling cascade	63/2619	315/18670	0.002056	0.0203	0.01523	TPD52L1/AKR1B1/SFRP1/SPHK1/MAP3K5/RASGRP1/MAPK3/RIPK2/SKP1/SLAMF1/FAS/TNIP2/TNIK/STK10/HGF/SEMA3A/CCDC88C/EGFR/MAP3K11/PINK1/TNFRSF11A/BIRC7/SEMA4C/DNAJA1/PTPN22/PTGER4/MAP4K1/CRYAB/MAP3K8/NFKB1/FOXM1/CD27/DAXX/TRIB1/AGT/MAPK11/CHUK/MYC/TAOK1/MAP4K4/IRAK4/EPHA4/MFHAS1/VEGFA/UBB/HMGB1/CCR7/NOD2/ARL6IP5/MAPKAPK2/MAP3K3/NCOR1/CYLD/IL1RN/TAOK3/NOD1/IKBKG/PAK2/PHLPP1/PTK2B/FZD7/CD40LG/NCF1	63
BP	GO:0002285	lymphocyte activation involved in immune response	40/2619	181/18670	0.002059	0.0203	0.01523	PARP3/LCP1/TFRC/IL27RA/RIPK2/PLCG2/ERCC1/NBN/MALT1/HLA-F/RORA/RAB27A/SEMA4A/IL4R/PTPRC/GPR183/ITGAL/DOCK10/ADA/THOC1/LEF1/CD28/CD40/PTGER4/RC3H2/CD81/RELB/IFNG/LY9/VAMP7/IL6/SLC11A1/CD19/TNFSF4/HMGB1/BATF/LGALS3/XBP1/PTK2B/CD40LG	40
BP	GO:0006261	DNA-dependent DNA replication	35/2619	153/18670	0.002062	0.02031	0.01523	BAZ1A/CDC7/FBXW7/NBN/RFWD3/POLD2/RECQL/CHEK2/DNA2/ORC3/ZNF365/RPA1/THOC1/DDX11/DBF4/SAMHD1/RPA3/ORC6/POLD4/DONSON/SETMAR/RPAIN/GINS1/POLG/BRCA2/ATRX/MCMBP/WRN/SMC1A/TIMELESS/CDK9/STOML2/RFC2/HMGA1/FBXO5	35
BP	GO:0098813	nuclear chromosome segregation	54/2619	262/18670	0.002103	0.02067	0.0155	ECT2/FBXW7/TUBG2/NIPBL/ATM/DLGAP5/PTTG1/RACGAP1/ACTR3/TPR/DDX11/BUB1B/NUSAP1/SPAG5/LCMT1/SMC5/RMI1/NCAPH/CDCA8/CHMP6/KIF18B/PRC1/NDC80/CENPE/CHMP2A/NAA50/CCNB1/NCAPG/MIS12/KIF4A/CDC20/ATRX/AURKB/DYNC1H1/RAD51C/TOP2A/MCMBP/SFPQ/KPNB1/SMC4/KATNB1/AKAP8/SMC1A/NDC1/CHMP1B/TACC3/CENPC/SPICE1/ACTR2/PTTG2/CENPF/NUP62/POGZ/FBXO5	54
BP	GO:0006473	protein acetylation	44/2619	204/18670	0.002108	0.02067	0.0155	BAZ1A/NUPR1/SPHK1/MAPK3/SNCA/NCOA3/CHEK1/NAP1L2/TADA3/GSK3B/MSL3/SET/BLOC1S1/LEF1/SETD5/ZNF451/EID1/MSL2/ARRB1/AUTS2/TAF10/MDH2/NAA16/BRPF1/TRRAP/NAA50/TAOK1/ELP3/BRCA2/TAF9B/TAF7/RUVBL2/KAT6A/KAT5/CAMK1/YEATS2/OGT/PRKAA1/KAT2B/ATF2/EP300/PIWIL2/MORF4L1/TWIST1	44
BP	GO:0031396	regulation of protein ubiquitination	44/2619	204/18670	0.002108	0.02067	0.0155	TNFAIP3/DYSF/SPHK1/BIRC3/FBXW7/RIPK2/MYCBP2/ANGPT1/MALT1/HERPUD1/FANCI/TRIP12/NMI/PINK1/BIRC2/CHFR/BIRC7/NDFIP1/DNAJA1/RNF111/PTPN22/ARRB1/ADRB2/PELI1/DAXX/TSPO/CDC20/PIN1/UBB/GLMN/NOD2/AIMP2/PSMD10/OGT/BCL10/N4BP1/TSPYL5/CRY1/UBR5/CDK9/HSPA5/WDR70/DCUN1D1/FBXO5	44
BP	GO:0043433	negative regulation of DNA-binding transcription factor activity	38/2619	170/18670	0.00212	0.02075	0.01556	ADORA3/TNFAIP3/AIM2/NFKBIA/SIK1/NUPR1/IRAK3/CD200/DAP/SRI/MED13/EZH2/PRNP/CTNNBIP1/PIM1/CARD8/MDFI/CAT/ARRB1/PELI1/TRIB1/TRIM21/CHUK/XCL1/TNFSF4/TRAF3/PEX14/PSMD10/PRDX2/CYLD/CEBPG/ID2/ID3/TCF7L2/FZD6/FLNA/DDIT3/TWIST1	38
BP	GO:0097305	response to alcohol	49/2619	233/18670	0.00214	0.02092	0.01569	SFRP1/PEMT/USP46/PMVK/SDF4/RBP4/BAD/GRAMD1C/NQO1/CDK4/BIRC2/FDX1/CCR5/PENK/EFNA5/HPGD/PPARG/PTGER4/PTGFR/MAP4K1/GGH/CAT/CD27/OXCT1/ITPR2/RGS4/CRHBP/AKR1C3/RPL10A/ADCY1/ABCA2/TNFSF4/CCR7/NFE2L1/SOD1/AKAP8/PRKAA1/ADCY2/TYMS/CDK1/CDKN1A/CCL7/CSN1S1/PTK2B/HNRNPD/SMO/ACTR2/ATP2B1/TH	49
BP	GO:0010876	lipid localization	77/2619	400/18670	0.002146	0.02094	0.01571	NFKBIA/DYSF/NME4/ENPP1/LIPC/APOLD1/FBXW7/APOL3/STOML1/CLU/SIGMAR1/OSBPL3/APOM/PLA2G2D/SERPINA5/FTO/ATP8B1/APOL1/SLC27A6/RBP4/ABCC4/ABCA8/GRAMD1C/EGF/APOL6/TNFRSF11A/APOE/MEST/GULP1/ABCA3/SLC27A5/RXRA/PITPNC1/OSBPL8/TMEM30A/APOO/HNRNPK/PCTP/PPARG/UGCG/PTPN2/SLCO3A1/NFKB1/APOC1/AGT/ABCC1/TSPO/NR1H2/VAMP7/IL6/APOL2/SCP2/ABCA2/GM2A/ATP8A1/P2RX4/PLA2R1/ABCA11P/ATP11B/NCOR1/ABCB1/LPL/TMF1/NMB/TAC1/GDF9/ATP10A/GAL/PLIN2/CRY1/LIMA1/FABP3/AKR1C4/NPC1/STOML2/PSAP/STARD7	77
BP	GO:0050867	positive regulation of cell activation	76/2619	394/18670	0.002159	0.02103	0.01577	CEBPA/TREM2/CD320/JAK2/CCL5/BTN2A2/RASGRP1/TFRC/IGFBP2/RIPK2/MALT1/IL15/HLA-F/HLA-G/TNIP2/IL7R/IL4R/LILRB2/PTPRC/CD38/GPR183/LILRA2/BAD/HSPH1/CTLA4/NCK2/ADA/RUNX3/TNFRSF14/CD83/HLA-E/SOCS1/IGHM/CD28/IL1RL2/FGR/CD40/TOX/ZAP70/MAP3K8/PNP/CD81/PELI1/TRBC1/CD3E/CD27/IFNG/LCK/IGF1/EFNB1/VAMP7/IL6/AXL/TYROBP/XCL1/TNFSF4/HMGB1/CCR7/PRKCQ/NOD2/IGLL5/IGLC1/CYLD/CD2/TAC1/IL6R/TNFSF14/VNN1/PAK2/BCL10/CDKN1A/XBP1/RPS6KA1/CCR2/CD40LG/PIK3CA	76
BP	GO:0051289	protein homotetramerization	24/2619	94/18670	0.002182	0.02122	0.01591	SYT11/PCBD1/CBY1/IMPDH2/HSD17B10/ACOT13/GPX3/DPYS/IDE/RXRA/SAMHD1/KCNJ2/CAT/PFKM/ALDH9A1/CRYZ/CD247/ALDH1A3/PKD2L1/PEX14/SRR/AQP2/MCOLN1/CRTC3	24
BP	GO:0002704	negative regulation of leukocyte mediated immunity	15/2619	49/18670	0.00219	0.02127	0.01595	PARP3/HLA-F/HLA-G/IL7R/PTPRC/THOC1/HLA-E/HFE/CD96/FOXF1/CR1/XCL1/C4BPB/IL13RA2/CCR2	15
BP	GO:1901654	response to ketone	42/2619	193/18670	0.002202	0.02135	0.01601	AKR1B1/SFRP1/PTN/AR/CFLAR/CD38/DDIT4/GABRB1/BAD/EGFR/CDK4/FDX1/EFNA5/CSNK2B/PPARG/PTGER4/PTGFR/MAP4K1/ASS1/TSPO/NASP/GHSR/AKR1C3/PSPH/ADCY1/CPS1/PCK2/CASP9/USP8/TNFSF4/CCR7/AKAP8/PRKAA1/ADCY2/TYMS/CDKN1A/CSN1S1/HNRNPD/ABHD2/SERPINF1/ATP2B1/TH	42
BP	GO:0006506	GPI anchor biosynthetic process	11/2619	31/18670	0.002287	0.02212	0.01659	PIGT/GPAA1/PIGK/PGAP2/PIGA/PIGP/DPM3/PIGH/PIGZ/PIGC/PGAP3	11
BP	GO:0006338	chromatin remodeling	40/2619	182/18670	0.002288	0.02212	0.01659	BAZ1A/JARID2/KDM5A/SMCHD1/SOX9/CHD1/CHD8/CHEK1/SMARCD3/TPR/ZNHIT1/ARID1A/DAXX/HMGB3/NASP/MYC/BAZ2B/TOP1/ATRX/SATB1/PBRM1/HMGB1/HJURP/CENPT/CHD3/RUVBL2/PTMA/SMARCA5/HDAC1/SMARCD2/PADI2/SUV39H2/BPTF/NPM3/CENPC/KAT2B/BAZ2A/HMGA1/HMGA2/SATB2	40
BP	GO:0032663	regulation of interleukin-2 production	16/2619	54/18670	0.002304	0.02224	0.01668	TNFAIP3/GBP1/PRKD2/RIPK2/MALT1/PTPRC/PRNP/CD83/CD28/CD3E/XCL1/GLMN/PRKCQ/HOMER3/KAT5/CCR2	16
BP	GO:0002718	regulation of cytokine production involved in immune response	22/2619	84/18670	0.002316	0.02226	0.01669	IRAK3/TNFRSF1B/MAPK3/ANGPT1/TRIL/MALT1/HLA-F/HLA-G/TNFRSF14/HLA-E/HFE/CD96/CD81/IL6/XCL1/CUEDC2/TNFSF4/NOD2/DDX1/DDX21/BCL10/CCR2	22
BP	GO:0006368	transcription elongation from RNA polymerase II promoter	22/2619	84/18670	0.002316	0.02226	0.01669	WDR61/POLR2J/POLR2I/POLR2L/EZH2/POLR2E/POLR2F/POLR2C/CCNT2/CTDP1/CCNH/ELP3/POLR2G/PBRM1/ELL2/CCNK/ERCC2/SETD2/NCBP2/MNAT1/GTF2H3/CDK9	22
BP	GO:0010507	negative regulation of autophagy	22/2619	84/18670	0.002316	0.02226	0.01669	NUPR1/TREM2/DAP/SNCA/HGF/MTMR9/CTSA/PINK1/RRAGA/SEC22B/HERC1/HTR2B/PTPN22/POLDIP2/TSPO/RASIP1/NAMPT/UBQLN4/MCL1/NPC1/CLEC16A/PIK3CA	22
BP	GO:0045185	maintenance of protein location	26/2619	105/18670	0.002334	0.02239	0.01679	NFKBIA/GPAA1/VPS13C/SKP1/SRI/CLMN/KDELR3/ARL2/SYNE2/BARD1/PINK1/MDFI/ANK3/BBS4/TSPO/NBL1/PML/ARL2BP/SCIN/TMSB10/PSMD10/TLN2/GOLPH3/FLNA/HSPA5/SRGN	26
BP	GO:0010976	positive regulation of neuron projection development	57/2619	281/18670	0.002351	0.02252	0.01689	PTN/SCN1B/SETX/NDNF/STMN2/SEMA4D/MACF1/CFLAR/HGF/SS18L1/EZH2/TUBB2B/ITSN2/BAIAP2/NTRK2/APOE/EFNA5/TMEM30A/MAGI2/TRAK1/PARP6/CXCR4/SYT17/NTRK1/AGT/PRKCI/VAMP7/RND2/EPHA4/VEGFA/PLXND1/ARHGAP35/TENM3/CAMK1/KATNB1/GOLGA4/NGFR/TRPV2/CDKL5/PLXNA1/SYT1/CYFIP1/EP300/CAPRIN2/PTK2B/STYXL1/DSCAM/FBXO38/C21orf91/SERPINF1/CAMK2B/ACTR2/HSPA5/CPNE6/BDNF/ARSB/NEDD4L	57
BP	GO:0048659	smooth muscle cell proliferation	38/2619	171/18670	0.002365	0.02262	0.01697	TNFAIP3/AKR1B1/STAT1/MAP3K5/JAK2/CCL5/IGFBP5/IL15/DNMT1/PDE1A/ABCC4/EGFR/COMT/CTNNBIP1/BMP4/HPGD/PPARG/GPER1/S1PR1/ELANE/NDRG2/IFNG/TRIB1/AGT/IGF1/ANG/IL6/HBEGF/IRAK4/NAMPT/EREG/PDGFB/IL6R/ID2/TCF7L2/CDKN1A/MNAT1/FOXJ2	38
BP	GO:0033619	membrane protein proteolysis	17/2619	59/18670	0.002376	0.02269	0.01702	TNFRSF1B/ADAM19/ADAM17/TIMP2/APOE/ROCK1/NFKB1/IFNG/MBTPS1/PSENEN/TIMP4/PRKCQ/NGFR/APH1B/TIMP1/APH1A/LRIG2	17
BP	GO:0018105	peptidyl-serine phosphorylation	60/2619	299/18670	0.002387	0.02276	0.01707	CDC7/PRKD2/MAPK3/RIPK2/TBK1/ANGPT1/SNCA/PRKCB/ATR/CHEK2/HGF/DDIT4/ATM/DYRK4/EGFR/PFN2/NCK2/PINK1/PRKCH/NTRK2/PRKX/GSK3B/NTF3/MAPK7/DYRK2/ROCK1/MAP4K1/ARRB1/CD44/IFNG/PLK2/CHUK/PRKCI/CCNB1/IL6/VRK2/TOP1/PDGFB/CSNK1A1/AURKB/VEGFA/CALCR/PRKCQ/CSNK1E/NLK/MAPKAPK2/CAMK1/MKNK2/AKAP9/PRKAA1/ATP2B4/RAF1/CDK1/PAK2/GGNBP2/CAPRIN2/MARK3/CLK1/HMGA2/PIK3CA	60
BP	GO:0031670	cellular response to nutrient	20/2619	74/18670	0.002404	0.02283	0.01713	SFRP1/PDK2/PTN/FOLR1/IL15/BAIAP2/PIM1/PENK/MED1/PPARG/POSTN/FOLR2/TRIM24/P2RX4/SOD1/LPL/XBP1/KANK2/BCL11A/ATP2B1	20
BP	GO:0048247	lymphocyte chemotaxis	18/2619	64/18670	0.002413	0.02283	0.01713	CXCL10/CCL5/CXCL13/CH25H/CCL18/CXCL11/GPR183/ADAM17/CYP7B1/CCL8/XCL1/CCL13/PADI2/PIK3CD/TNFSF14/CCL7/PTK2B/CCR2	18
BP	GO:0060135	maternal process involved in female pregnancy	18/2619	64/18670	0.002413	0.02283	0.01713	AKR1B1/PTN/AR/MAPK3/BSG/STC1/ANGPT2/RXRA/MED1/LDOC1/APOL2/GHSR/PRDM1/TMED2/AGRP/DAZAP1/STC2/EPOR	18
BP	GO:0009415	response to water	7/2619	15/18670	0.002424	0.02283	0.01713	AKR1B1/NTRK1/PKD2L1/AQP2/ATP2B4/ATF2/TH	7
BP	GO:0033151	V(D)J recombination	7/2619	15/18670	0.002424	0.02283	0.01713	DCLRE1C/TCF7/ATM/BCL11B/LEF1/HMGB1/TCF3	7
BP	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase	7/2619	15/18670	0.002424	0.02283	0.01713	ECI2/ACOX2/DECR2/SCP2/ACOX1/ACOT8/CRAT	7
BP	GO:0042976	activation of Janus kinase activity	7/2619	15/18670	0.002424	0.02283	0.01713	JAK2/CCL5/SOCS1/AGT/IL6R/GHR/PTK2B	7
BP	GO:2001028	positive regulation of endothelial cell chemotaxis	7/2619	15/18670	0.002424	0.02283	0.01713	LGMN/PRKD2/HSPB1/FGF18/KDR/VEGFA/P2RX4	7
BP	GO:0002819	regulation of adaptive immune response	36/2619	160/18670	0.002428	0.02284	0.01713	TNFAIP3/HLA-C/PARP3/IRF1/TNFRSF1B/TFRC/IL27RA/RIPK2/MALT1/HLA-F/HLA-G/IL7R/HLA-A/IL4R/PTPRC/ADA/THOC1/TNFRSF14/HLA-B/HLA-E/HFE/CD28/CD40/RC3H2/CD81/CR1/IL6/XCL1/SLC11A1/TNFSF4/HMGB1/C4BPB/PRKCQ/IL6R/CCR2/FBXO38	36
BP	GO:0039528	cytoplasmic pattern recognition receptor signaling pathway in response to virus	10/2619	27/18670	0.002495	0.02326	0.01744	RNF125/BIRC3/PUM2/BIRC2/TSPAN6/IRF3/GPATCH3/DDX60/SEC14L1/RIOK3	10
BP	GO:0043921	modulation by host of viral transcription	10/2619	27/18670	0.002495	0.02326	0.01744	CCL5/CHD1/RRP1B/LEF1/CTDP1/PSMC3/HDAC1/TARDBP/EP300/HMGA2	10
BP	GO:0052472	modulation by host of symbiont transcription	10/2619	27/18670	0.002495	0.02326	0.01744	CCL5/CHD1/RRP1B/LEF1/CTDP1/PSMC3/HDAC1/TARDBP/EP300/HMGA2	10
BP	GO:0061437	renal system vasculature development	10/2619	27/18670	0.002495	0.02326	0.01744	NOTCH1/ANGPT1/CFLAR/ANGPT2/PECAM1/BMP4/EGR1/PDGFB/IL6R/GPR4	10
BP	GO:0061440	kidney vasculature development	10/2619	27/18670	0.002495	0.02326	0.01744	NOTCH1/ANGPT1/CFLAR/ANGPT2/PECAM1/BMP4/EGR1/PDGFB/IL6R/GPR4	10
BP	GO:1901623	regulation of lymphocyte chemotaxis	10/2619	27/18670	0.002495	0.02326	0.01744	CXCL10/CCL5/CXCL13/ADAM17/XCL1/PADI2/TNFSF14/CCL7/PTK2B/CCR2	10
BP	GO:0031330	negative regulation of cellular catabolic process	54/2619	264/18670	0.002498	0.02326	0.01744	NUPR1/NELL1/TREM2/DAP/SNCA/LAMP3/CIRBP/GABARAPL2/ATRAID/HGF/CBFA2T3/DDIT4/MTMR9/CTSA/UBE2J1/PINK1/TIMP2/HNRNPA0/RRAGA/HFE/SEC22B/HERC1/HTR2B/PTPN22/ROCK1/FHIT/POLDIP2/APOC1/TSPO/RASIP1/PML/NAMPT/EPHA4/SLC11A1/UBQLN4/TIMP4/MAPKAPK2/DND1/MCL1/OGT/YBX1/TARDBP/ATP2B4/RYBP/TIMP1/N4BP1/MYD88/HNRNPD/NPC1/CLEC16A/LRIG2/USP14/DAZL/PIK3CA	54
BP	GO:0042102	positive regulation of T cell proliferation	24/2619	95/18670	0.002538	0.02359	0.0177	CCL5/TFRC/IGFBP2/RIPK2/IL15/LILRB2/PTPRC/NCK2/HLA-E/CD28/ZAP70/PNP/CD81/CD3E/IGF1/EFNB1/IL6/XCL1/TNFSF4/HMGB1/PRKCQ/IL6R/CCR2/CD40LG	24
BP	GO:1900271	regulation of long-term synaptic potentiation	14/2619	45/18670	0.002569	0.02382	0.01786	PTN/LGMN/LILRB2/PRNP/CX3CR1/APOE/GSK3B/ADCY1/TYROBP/EPHA4/NRGN/CALB2/CREB1/STAU1	14
BP	GO:0009755	hormone-mediated signaling pathway	49/2619	235/18670	0.00257	0.02382	0.01786	SFRP1/AR/JAK2/UFSP2/RORA/NCOA3/NCOA6/TADA3/RXRA/BMP4/CYP7B1/DNAJA1/LEF1/CSNK2B/MED1/PPARG/KDM3A/PHB/GPER1/ARID1A/YWHAH/LMO3/DAXX/CRHBP/NR1H2/GHSR/NR3C2/TAF7/BUD31/NR2F1/LGR5/SSTR5/KAT5/PGRMC2/NCOR1/AGRP/HDAC1/PADI2/AKAP13/RNF14/FHL2/EP300/CRY1/UBR5/ABHD2/NR5A2/KANK2/NUP62/NR1D2	49
BP	GO:0002697	regulation of immune effector process	86/2619	458/18670	0.002588	0.02395	0.01796	SLAMF8/TNFAIP3/AIM2/RNF125/C7/HLA-C/IRAK3/PARP3/STAT1/TNFRSF1B/DNASE1L3/BIRC3/RASGRP1/TFRC/IL27RA/MAPK3/RIPK2/PROS1/ANGPT1/CLU/TRIL/MALT1/IL15/HLA-F/HLA-G/MICB/IL7R/HLA-A/SUSD4/IL4R/PTPRC/RBP4/PUM2/THOC1/TNFRSF14/BIRC2/HLA-B/HLA-E/HFE/HTRA1/IGLV1-44/TSPAN6/CD96/CD28/CRTAM/CFI/PHB/FGR/CD40/RC3H2/FOXF1/CD81/MZB1/CR1/IFNG/RAC2/VAMP7/IL6/GPATCH3/XCL1/CD19/MMP12/CUEDC2/TNFSF4/HMGB1/C4BPB/NOD2/TRAF3/ULBP2/PPM1B/IGLC1/DDX1/DDX60/DDX21/SEC14L1/LGALS3/BCL10/XBP1/RIOK3/IL13RA2/CCR2/FBXO38/CD40LG/CFP/TSPAN32/CD59	86
BP	GO:0034101	erythrocyte homeostasis	29/2619	122/18670	0.002626	0.02414	0.01811	P4HTM/STAT1/JAK2/ADAR/IREB2/KIT/BMP4/EPB42/HOXB6/MED1/JMJD6/PTPN2/PTBP3/AXL/MFHAS1/DNASE2/ZNF16/VEGFA/ARID4A/NFE2L1/HIF1A/HOXA5/ERCC2/CEBPG/ID2/SFXN1/SH2B3/AMPD3/TRIM58	29
BP	GO:0031058	positive regulation of histone modification	23/2619	90/18670	0.002633	0.02414	0.01811	MTF2/JARID2/PRKD2/MAPK3/NIPBL/WDR61/DNMT1/ATM/NAP1L2/PINK1/SART3/ING2/ARRB1/AUTS2/CCNB1/VEGFA/EED/PAXBP1/RUVBL2/AKAP8/OGT/PIWIL2/CDK9	23
BP	GO:0071674	mononuclear cell migration	23/2619	90/18670	0.002633	0.02414	0.01811	SLAMF8/CXCL10/LGMN/CCL5/MAPK3/CCL18/SERPINE1/TNFRSF11A/PECAM1/CREB3/PLA2G7/CCL8/NBL1/IL6/PDGFB/XCL1/HMGB1/CCL13/IL6R/S100A12/LGALS3/CCL7/CCR2	23
BP	GO:0042451	purine nucleoside biosynthetic process	9/2619	23/18670	0.002636	0.02414	0.01811	NME4/NME7/IMPDH2/NME5/ADK/ADA/NME3/GUK1/NT5E	9
BP	GO:0046129	purine ribonucleoside biosynthetic process	9/2619	23/18670	0.002636	0.02414	0.01811	NME4/NME7/IMPDH2/NME5/ADK/ADA/NME3/GUK1/NT5E	9
BP	GO:0048714	positive regulation of oligodendrocyte differentiation	9/2619	23/18670	0.002636	0.02414	0.01811	PTN/TNFRSF1B/ZNF365/PRMT5/PPARG/CXCR4/HDAC1/OLIG2/TENM4	9
BP	GO:0071305	cellular response to vitamin D	9/2619	23/18670	0.002636	0.02414	0.01811	SFRP1/PTN/IL15/PIM1/PENK/MED1/TRIM24/KANK2/ATP2B1	9
BP	GO:0072576	liver morphogenesis	8/2619	19/18670	0.002644	0.02418	0.01814	TNFAIP3/PTN/FBXW7/CFLAR/MED1/XBP1/RPS6KA1/CEBPB	8
BP	GO:0006361	transcription initiation from RNA polymerase I promoter	12/2619	36/18670	0.00269	0.02453	0.0184	MAPK3/POLR2L/POLR2E/POLR2F/TAF1D/POLR1B/CCNH/ERCC2/MNAT1/POLR1C/GTF2H3/BAZ2A	12
BP	GO:0035872	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	12/2619	36/18670	0.00269	0.02453	0.0184	TNFAIP3/NFKBIA/BIRC3/RIPK2/BIRC2/PTPN22/UBB/NOD2/CYLD/NOD1/IKBKG/RNF34	12
BP	GO:0048864	stem cell development	22/2619	85/18670	0.002719	0.02473	0.01855	FOLR1/SOX9/SEMA4D/MAPK3/SEMA4A/PTPRC/FOXC1/SEMA3A/BMP4/SEMA4C/HTR2B/FAM172A/LAMA5/SEMA3F/EFNB1/SEMA3E/PHACTR4/HIF1A/SETD2/ERBB4/SMO/TWIST1	22
BP	GO:2001057	reactive nitrogen species metabolic process	22/2619	85/18670	0.002719	0.02473	0.01855	GCH1/GCHFR/JAK2/CLU/SMAD3/DDAH1/RORA/CX3CR1/NQO1/INSR/SUOX/DDAH2/IFNG/AGT/ASS1/TSPO/NOS3/CPS1/P2RX4/HBB/ATP2B4/PTK2B	22
BP	GO:0070671	response to interleukin-12	15/2619	50/18670	0.002729	0.02478	0.01859	LCP1/JAK2/RIPK2/HNRNPA2B1/TYK2/RALA/CAPZA1/JAK1/LMNB1/STAT4/IFNG/SOD1/PAK2/RAP1B/RPLP0	15
BP	GO:0016579	protein deubiquitination	57/2619	283/18670	0.00277	0.02512	0.01884	TNFAIP3/NFKBIA/AR/BIRC3/USP11/USP46/SMAD3/CCNA2/TNIP2/ATXN7/TNIP1/UCHL1/PSMB9/TNIP3/BARD1/USP3/USP24/TADA3/SART3/BIRC2/PSMC2/USP47/USP32/USP34/ADRB2/TAF10/PSMB6/USP27X/TRIM21/ASXL2/TRRAP/PSMC3/MYC/TAF9B/CDC20/USP8/PSMD8/UBB/UCHL3/PSMB5/TRAF3/DDB2/PSMD10/HIF1A/USP9X/USP12/OGT/CYLD/IKBKG/BABAM1/USP48/CDK1/KAT2B/EP300/NEDD8/USP21/USP14	57
BP	GO:0016049	cell growth	90/2619	484/18670	0.002798	0.02533	0.019	KAZALD1/SFRP1/SPHK1/SOX9/ENPP1/IGFBP5/SEMA4D/FBLN5/MACF1/SMAD3/SEMA4A/NDUFA13/SPOCK1/CD38/SEMA3A/ADAM17/SPG11/FGF13/CDKN2C/EGFR/ITSN2/NDN/APOE/GSK3B/IGFBP4/SEMA4C/ERBB2/EFNA5/WNT11/LEF1/USP47/CYFIP2/PPARG/PHB/CXCR4/CRYAB/SYT17/FGFR1OP/AUTS2/POSTN/RGS4/AGT/SEMA3F/CTDP1/IGF1/CRLF3/RND2/HBEGF/TAF9B/PML/SORBS2/VEGFA/PIN1/IL17RB/PLCE1/PRKCQ/LAMTOR2/SEMA3E/NET1/LTBP4/PSMD10/USP9X/DNPH1/CTTN/CIB1/GOLGA4/GDF9/TRPV2/TNK1/AKAP13/NDUFS3/GAL/CDKL5/PLXNA1/SYT1/CDKN1A/CYFIP1/TRIM32/CAPRIN2/RASGRP2/RPS6KA1/PTK2B/DSCAM/CPNE6/BCL11A/BDNF/CISH/CHPT1/TMEM97/NEDD4L	90
BP	GO:0070665	positive regulation of leukocyte proliferation	32/2619	139/18670	0.00281	0.02541	0.01906	CD320/CCL5/TFRC/IGFBP2/RIPK2/IL15/LILRB2/PTPRC/CD38/GPR183/NCK2/ADA/HLA-E/CD28/CD40/ZAP70/PNP/CD81/PELI1/CD3E/IGF1/EFNB1/IL6/XCL1/TNFSF4/HMGB1/PRKCQ/TAC1/IL6R/CDKN1A/CCR2/CD40LG	32
BP	GO:0048661	positive regulation of smooth muscle cell proliferation	25/2619	101/18670	0.002817	0.02543	0.01907	AKR1B1/STAT1/MAP3K5/JAK2/CCL5/IGFBP5/DNMT1/ABCC4/EGFR/BMP4/HPGD/S1PR1/ELANE/AGT/IGF1/IL6/HBEGF/IRAK4/NAMPT/EREG/PDGFB/IL6R/ID2/MNAT1/FOXJ2	25
BP	GO:0061098	positive regulation of protein tyrosine kinase activity	16/2619	55/18670	0.002833	0.02554	0.01916	CCL5/FBXW7/ADAM17/EGF/PRNP/NTRK2/NEDD9/AGT/EREG/PDGFB/EPHA4/ABI1/DOCK3/PAK2/BDNF/NCF1	16
BP	GO:0150076	neuroinflammatory response	20/2619	75/18670	0.002854	0.02569	0.01927	NUPR1/SPHK1/TREM2/CD200/TNFRSF1B/JAK2/SNCA/CLU/PTPRC/ATM/EGFR/IFNG/IGF1/IL6/ADCY1/NAMPT/TYROBP/CST7/TLR8/SMO	20
BP	GO:0046794	transport of virus	17/2619	60/18670	0.00289	0.02594	0.01946	VPS37C/NUP160/NUP153/KPNA2/TPR/NUP50/SEC13/RANBP2/NUP210/UBB/KPNB1/NUP43/NDC1/KPNA1/KPNA3/NUP98/NUP62	17
BP	GO:0051784	negative regulation of nuclear division	17/2619	60/18670	0.00289	0.02594	0.01946	TOM1L1/CHEK1/ATM/PTTG1/TPR/BMP4/BUB1B/LCMT1/NDC80/CCNB1/CDC20/ATRX/AURKB/RAD1/PTTG2/CENPF/FBXO5	17
BP	GO:0002696	positive regulation of leukocyte activation	73/2619	380/18670	0.002902	0.02597	0.01948	CEBPA/TREM2/CD320/CCL5/BTN2A2/RASGRP1/TFRC/IGFBP2/RIPK2/MALT1/IL15/HLA-F/HLA-G/TNIP2/IL7R/IL4R/LILRB2/PTPRC/CD38/GPR183/BAD/HSPH1/CTLA4/NCK2/ADA/RUNX3/TNFRSF14/CD83/HLA-E/SOCS1/IGHM/CD28/IL1RL2/FGR/CD40/TOX/ZAP70/MAP3K8/PNP/CD81/PELI1/TRBC1/CD3E/CD27/IFNG/LCK/IGF1/EFNB1/VAMP7/IL6/AXL/TYROBP/XCL1/TNFSF4/HMGB1/CCR7/PRKCQ/NOD2/IGLL5/IGLC1/CYLD/CD2/TAC1/IL6R/TNFSF14/VNN1/PAK2/BCL10/CDKN1A/XBP1/CCR2/CD40LG/PIK3CA	73
BP	GO:0001933	negative regulation of protein phosphorylation	81/2619	429/18670	0.002904	0.02597	0.01948	TNFAIP3/GBP1/DUSP5/SFRP1/CEBPA/MICAL1/IRAK3/BTN2A2/ENPP1/SEMA4D/ADAR/PRKAR2A/ANGPT1/SNCA/DUSP6/TNIP1/UCHL1/PTPRC/HGF/DDIT4/PID1/CDKN2C/DEPTOR/PRNP/NCK2/PINK1/APOE/CHORDC1/ATF3/NTF3/SOCS1/CTDSPL/LAX1/BMP4/DNAJA1/PTPN22/PHB/FKBP8/GPER1/PTPN2/CHMP6/FGFR1OP/ARRB1/HSPB1/CBLB/FOXM1/NDRG2/IFNG/PRR5L/LMO3/RGS4/TRIB1/SIRT3/PPM1E/LRP5/INSM1/CCNB1/MYC/RASIP1/CDKN1C/TAF7/DUSP2/EIF3A/PIN1/NCOR1/DNAJC3/PSMD10/CYLD/NF2/TARDBP/TAOK3/CIB1/PAK2/GGNBP2/KAT2B/CDKN1A/FBLN1/SH2B3/MVP/TWIST1/NUP62	81
BP	GO:0016573	histone acetylation	35/2619	156/18670	0.002905	0.02597	0.01948	BAZ1A/MAPK3/SNCA/NCOA3/CHEK1/NAP1L2/TADA3/MSL3/SET/LEF1/SETD5/ZNF451/EID1/MSL2/ARRB1/AUTS2/TAF10/BRPF1/TRRAP/NAA50/ELP3/BRCA2/TAF9B/TAF7/RUVBL2/KAT6A/KAT5/YEATS2/OGT/KAT2B/ATF2/EP300/PIWIL2/MORF4L1/TWIST1	35
BP	GO:0097327	response to antineoplastic agent	24/2619	96/18670	0.002943	0.02627	0.0197	CFLAR/DDIT4/EGFR/CDK4/DDX11/MAP4K1/DAXX/ASS1/GHSR/EGR1/CPS1/ATRX/PDGFB/PCK2/CASP9/HNRNPA1/USP8/TIMELESS/PRKAA1/ADIRF/NUCB1/HNRNPD/SERPINF1/ASNS	24
BP	GO:0007160	cell-matrix adhesion	47/2619	225/18670	0.002988	0.02652	0.01989	SFRP1/FBLN5/TRIP6/MACF1/SMAD3/ITGBL1/ITGAL/SERPINE1/GSK3B/CORO2B/LIMCH1/PECAM1/EFNA5/CD96/ROCK1/ITGB7/LAMA5/CD44/TMEM8B/FERMT2/POSTN/CD3E/ARHGEF7/CD63/PIK3CB/KDR/MAP4K4/CLASP1/MYOC/MMP12/VEGFA/CCR7/FERMT1/SEMA3E/NINJ1/COL5A3/PTPRK/EMP2/NF2/CTTN/CIB1/ITGB5/COL3A1/ACTN1/PTK2B/HOXA7/SORBS1	47
BP	GO:0032355	response to estradiol	31/2619	134/18670	0.002993	0.02652	0.01989	SFRP1/PTN/IGFBP2/CCNA2/CFLAR/CD38/NCOA3/EZH2/BAD/EGFR/NQO1/PENK/TFPI/HPGD/GPER1/PTGFR/CRYAB/CAT/GPX4/POSTN/AGT/ASS1/CRHBP/GHSR/CASP9/RUVBL2/KAT5/BCL2L2/CSN1S1/HNRNPD/TH	31
BP	GO:0006308	DNA catabolic process	13/2619	41/18670	0.003	0.02652	0.01989	ERI3/DNASE1L3/ATM/DNASE1L1/ISG20/SETMAR/APAF1/IL6/DNASE2/HMGB1/KPNB1/DFFB/KPNA1	13
BP	GO:0010955	negative regulation of protein processing	13/2619	41/18670	0.003	0.02652	0.01989	BIRC3/GAS1/PRNP/SERPINE1/CARD8/BIRC2/BIRC7/NOL3/CR1/TMEM59/C4BPB/CST7/CD59	13
BP	GO:0045005	DNA-dependent DNA replication maintenance of fidelity	13/2619	41/18670	0.003	0.02652	0.01989	RFWD3/DNA2/ZNF365/THOC1/DDX11/SAMHD1/DONSON/SETMAR/BRCA2/ATRX/WRN/TIMELESS/CDK9	13
BP	GO:0050434	positive regulation of viral transcription	13/2619	41/18670	0.003	0.02652	0.01989	CHD1/POLR2J/POLR2I/POLR2L/POLR2E/POLR2F/RRP1B/LEF1/POLR2C/CTDP1/POLR2G/EP300/CDK9	13
BP	GO:1903318	negative regulation of protein maturation	13/2619	41/18670	0.003	0.02652	0.01989	BIRC3/GAS1/PRNP/SERPINE1/CARD8/BIRC2/BIRC7/NOL3/CR1/TMEM59/C4BPB/CST7/CD59	13
BP	GO:0006575	cellular modified amino acid metabolic process	43/2619	202/18670	0.003044	0.02676	0.02007	HPGDS/GCH1/GSTA4/P4HTM/FOLR1/DIO3/ALDH7A1/MTHFD2/BHMT2/GAMT/PEMT/SLC22A4/PLA2G2D/SLC7A11/GSTM4/OSBPL8/MED1/GSTZ1/GPX1/GGH/CRTAP/SERINC5/CPQ/GPX4/FOLR2/GATM/ASS1/ALDH9A1/GSTM5/AHCY/GSTM3/PLA1A/EGLN3/DIO2/ACADM/NFE2L1/SOD1/GGCT/TYMS/VNN1/GLO1/LPCAT4/CRAT	43
BP	GO:0006505	GPI anchor metabolic process	11/2619	32/18670	0.003049	0.02676	0.02007	PIGT/GPAA1/PIGK/PGAP2/PIGA/PIGP/DPM3/PIGH/PIGZ/PIGC/PGAP3	11
BP	GO:0031297	replication fork processing	11/2619	32/18670	0.003049	0.02676	0.02007	RFWD3/DNA2/ZNF365/THOC1/DDX11/SAMHD1/SETMAR/BRCA2/ATRX/WRN/CDK9	11
BP	GO:0038128	ERBB2 signaling pathway	11/2619	32/18670	0.003049	0.02676	0.02007	BTC/SOS1/EGFR/EGF/ERBB2/HBEGF/MYOC/EREG/MATK/ERBB4/PIK3CA	11
BP	GO:0071353	cellular response to interleukin-4	11/2619	32/18670	0.003049	0.02676	0.02007	IL2RG/IL4R/TCF7/IMPDH2/CDK4/LEF1/PTPN2/PML/XCL1/XBP1/HSPA5	11
BP	GO:0016999	antibiotic metabolic process	34/2619	151/18670	0.003108	0.02724	0.02043	AKR1B1/AKR1B10/SNCA/SDHC/ALDH1A1/GNPDA1/ME2/EGFR/PINK1/IREB2/GPX3/PRDX6/PXDN/GPX1/KDM3A/ESD/AKR7A2/CAT/MDH2/SDHD/DLD/RAC2/AKR1C3/PCK2/SULT1A2/SOD1/HBB/PDHB/PRDX2/SUCLG1/MDH1/AKR1C4/FH/ALDH3B1	34
BP	GO:0034614	cellular response to reactive oxygen species	37/2619	168/18670	0.003143	0.02751	0.02063	TNFAIP3/GCH1/PDK2/SPHK1/SETX/MAP3K5/ECT2/MAPK3/FBLN5/SIGMAR1/CCNA2/CFLAR/HGF/EZH2/EGFR/PINK1/NQO1/MAPK7/PLEKHA1/CHUK/ANKZF1/NOS3/IL6/AKR1C3/AXL/TRAP1/PTPRK/SOD1/NET1/PRDX2/PRKAA1/CDK1/MPV17/PYCR1/HNRNPD/PSAP/NCF1	37
BP	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	22/2619	86/18670	0.003179	0.02779	0.02084	TNFAIP3/SFRP1/FAS/CFLAR/CRADD/HGF/BAD/SERPINE1/ATF3/MADD/ARHGEF2/PEA15/GPX1/DAXX/NOS3/SORT1/CASP8AP2/FAIM/RAF1/LGALS3/GABARAP/RNF34	22
BP	GO:1903038	negative regulation of leukocyte cell-cell adhesion	30/2619	129/18670	0.003185	0.0278	0.02085	IRF1/SOCS6/BTN2A2/HLA-G/PLA2G2D/IL4R/LILRB2/TNFRSF21/CTLA4/IDO1/PRNP/RUNX3/TNFRSF14/SOCS1/HFE/LAX1/BMP4/ERBB2/PTPN22/PTPN2/RC3H2/PELI1/ASS1/XCL1/TNFSF4/HMGB1/GLMN/PRDX2/LGALS3/CEBPB	30
BP	GO:0044003	modification by symbiont of host morphology or physiology	14/2619	46/18670	0.003224	0.02806	0.02105	SMAD3/TNIP1/BAD/KPNA2/INSR/RRAGA/RXRA/CCL8/KPNB1/CCNK/TYMS/KPNA1/KPNA3/VAPA	14
BP	GO:0048599	oocyte development	14/2619	46/18670	0.003224	0.02806	0.02105	CDC25B/ATM/NPR2/IGF1/CCNB1/ANG/BRCA2/EREG/YTHDC2/GDF9/INHBB/PTK2B/DAZL/FBXO5	14
BP	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	25/2619	102/18670	0.003244	0.02806	0.02105	TNFAIP3/CEBPA/DIRAS3/CCNA2/ADAM17/CDKN2C/EGFR/CCNL1/CKS1B/CDK4/MAPRE3/CKS2/CCNT2/CCNB2/CCNB1/CCNH/CDKN1C/PDGFB/PSMD10/CCNK/CCND2/KAT2B/CDKN1A/MNAT1/CCNL2	25
BP	GO:0002367	cytokine production involved in immune response	25/2619	102/18670	0.003244	0.02806	0.02105	IRAK3/TNFRSF1B/MAPK3/ANGPT1/TRIL/MALT1/HLA-F/HLA-G/TNFRSF14/HLA-E/KIT/HFE/CD96/DENND1B/CD81/IL6/XCL1/SLC11A1/CUEDC2/TNFSF4/NOD2/DDX1/DDX21/BCL10/CCR2	25
BP	GO:0007015	actin filament organization	76/2619	400/18670	0.003247	0.02806	0.02105	SFRP1/MICAL1/IQGAP2/ACTR3B/LCP1/JAK2/ARPC1A/SMAD3/MICALL2/TMOD1/CDC42EP3/FCHSD2/PFN2/BAIAP2/NCK2/ACTR3/NEDD9/CORO2B/LIMCH1/PSTPIP2/MYOM2/CAPZA1/BIN1/RHOF/WNT11/FAT1/ARHGEF2/ROCK1/BBS4/PTGER4/NEBL/ARRB1/S1PR1/MICAL2/DIAPH2/RGS4/PPM1E/WIPF1/PRKCI/RAC2/ANG/TMOD2/RND2/GHSR/CLASP1/FHOD3/MAGEL2/MYOC/SORBS2/MSRB2/SCIN/ARHGAP35/CCR7/AP1AR/TMSB10/TTC17/ABI1/ALMS1/EMP2/ARPC5L/NF2/TAC1/CTTN/ITGB5/RHOH/HIP1R/CYFIP1/LIMA1/ACTN1/FLNA/PTK2B/ARFGEF1/ACTR2/EFS/GDPD2/SORBS1	76
BP	GO:0046488	phosphatidylinositol metabolic process	38/2619	174/18670	0.003251	0.02806	0.02105	PIGT/GPAA1/SOCS6/PLCG2/PIGK/PLA2G2D/MTMR4/PGAP2/ATM/MTMR9/SYNJ1/PIKFYVE/PIGA/SOCS1/PIGP/DPM3/HTR2B/SH3YL1/PLEKHA4/MTMR6/PIK3C2B/PLEKHA1/PLA2G4C/PIK3CB/PIK3R5/EFR3A/PDGFB/MTMR1/PIGH/PLBD1/PIGZ/PIK3CD/INPP5E/PIGC/PGAP3/PIK3C2G/CISH/PIK3CA	38
BP	GO:0002551	mast cell chemotaxis	6/2619	12/18670	0.003273	0.02806	0.02105	PGF/KIT/RAC2/VEGFA/PIK3CD/VEGFB	6
BP	GO:0006527	arginine catabolic process	6/2619	12/18670	0.003273	0.02806	0.02105	FAH/DDAH1/DDAH2/NOS3/OAT/ATP2B4	6
BP	GO:0038110	interleukin-2-mediated signaling pathway	6/2619	12/18670	0.003273	0.02806	0.02105	IL2RG/JAK1/PTPN2/IL2RB/STAT5A/PTK2B	6
BP	GO:0070486	leukocyte aggregation	6/2619	12/18670	0.003273	0.02806	0.02105	SEMA4D/STK10/CD44/ZAP70/RAC2/HAS2	6
BP	GO:0097340	inhibition of cysteine-type endopeptidase activity	6/2619	12/18670	0.003273	0.02806	0.02105	BIRC3/CARD8/BIRC2/BIRC7/NOL3/CST7	6
BP	GO:0097341	zymogen inhibition	6/2619	12/18670	0.003273	0.02806	0.02105	BIRC3/CARD8/BIRC2/BIRC7/NOL3/CST7	6
BP	GO:0097531	mast cell migration	6/2619	12/18670	0.003273	0.02806	0.02105	PGF/KIT/RAC2/VEGFA/PIK3CD/VEGFB	6
BP	GO:0007045	cell-substrate adherens junction assembly	21/2619	81/18670	0.003283	0.02807	0.02105	SFRP1/TRIP6/MACF1/SMAD3/CORO2B/LIMCH1/EFNA5/ROCK1/LAMA5/FERMT2/ARHGEF7/KDR/MAP4K4/CLASP1/MYOC/VEGFA/PTPRK/CTTN/ACTN1/PTK2B/SORBS1	21
BP	GO:0048041	focal adhesion assembly	21/2619	81/18670	0.003283	0.02807	0.02105	SFRP1/TRIP6/MACF1/SMAD3/CORO2B/LIMCH1/EFNA5/ROCK1/LAMA5/FERMT2/ARHGEF7/KDR/MAP4K4/CLASP1/MYOC/VEGFA/PTPRK/CTTN/ACTN1/PTK2B/SORBS1	21
BP	GO:0042278	purine nucleoside metabolic process	20/2619	76/18670	0.003372	0.02857	0.02143	NME4/NME7/GAMT/PEMT/IMPDH2/NT5C2/NME5/ADK/ADA/MACROD1/MOCS2/DGUOK/NME3/PNP/GUK1/AHCY/MPP1/TJP2/NT5E/AMPD3	20
BP	GO:0031214	biomineral tissue development	36/2619	163/18670	0.003373	0.02857	0.02143	PTN/NOTCH1/NELL1/SOX9/ENPP1/MGP/ANKH/SMAD3/ATRAID/PTH1R/LTBP3/BMP4/WNT11/ROCK1/FGR/TCIRG1/S1PR1/OSR2/ADRB2/IGF1/COMP/NOS3/MMP13/SNX10/HIF1A/ERCC2/MMP20/ZBTB40/PTK2B/CEBPB/ATF4/ATP2B1/TWIST1/SRGN/SBNO2/FBXO5	36
BP	GO:0045931	positive regulation of mitotic cell cycle	36/2619	163/18670	0.003373	0.02857	0.02143	CDC25B/SPHK1/LGMN/CDC7/NIPBL/BTC/ADAM17/DLGAP5/EGFR/EGF/SMARCD3/INSR/CDK4/TPR/NUSAP1/CD28/SMC5/POLDIP2/NDC80/PHIP/LRP5/IGF1/CCNB1/BRCA2/EREG/PDGFB/RAD51C/DTL/CDK1/CCND2/HSPA2/ASNS/RAD51B/MEPCE/NUP62/FBXO5	36
BP	GO:0001954	positive regulation of cell-matrix adhesion	15/2619	51/18670	0.003373	0.02857	0.02143	SFRP1/SMAD3/GSK3B/ROCK1/CD3E/KDR/MAP4K4/MYOC/VEGFA/CCR7/FERMT1/NINJ1/EMP2/CIB1/PTK2B	15
BP	GO:0009994	oocyte differentiation	15/2619	51/18670	0.003373	0.02857	0.02143	CDC25B/ATM/NPR2/IGF1/CCNB1/ANG/BRCA2/EREG/LGR5/YTHDC2/GDF9/INHBB/PTK2B/DAZL/FBXO5	15
BP	GO:0043484	regulation of RNA splicing	31/2619	135/18670	0.003375	0.02857	0.02143	SRPK1/SETX/HNRNPA2B1/CIRBP/CELF2/MBNL3/KHDRBS3/SART3/PRDX6/RRP1B/AKAP17A/FAM172A/CELF1/HNRNPK/JMJD6/FASTK/PTBP3/RBM15/TIA1/SFSWAP/SRSF4/PTBP2/HNRNPA1/SRSF8/RBM19/SREK1/YTHDC1/DAZAP1/SON/CLK1/NUP98	31
BP	GO:0051101	regulation of DNA binding	29/2619	124/18670	0.003385	0.02857	0.02143	NFKBIA/JAK2/FBXW7/SRI/NIPBL/FOXC1/EGF/CTNNBIP1/MDFI/LEF1/CSNK2B/PPARG/GZMA/TAF10/ID4/IFNG/IGF1/HMGB1/HJURP/ERCC2/IFI16/CEBPG/ID2/ID3/EP300/SMO/HMGA2/DDIT3/TWIST1	29
BP	GO:0009074	aromatic amino acid family catabolic process	10/2619	28/18670	0.0034	0.02857	0.02143	FAH/HPD/HAAO/QDPR/PCBD1/IDO1/ASRGL1/GSTZ1/HDC/HNMT	10
BP	GO:0010818	T cell chemotaxis	10/2619	28/18670	0.0034	0.02857	0.02143	CXCL10/CCL5/CXCL13/CXCL11/GPR183/ADAM17/XCL1/PIK3CD/TNFSF14/CCR2	10
BP	GO:0032647	regulation of interferon-alpha production	10/2619	28/18670	0.0034	0.02857	0.02143	STAT1/RIPK2/TBK1/NMI/IRF3/CHUK/MMP12/HMGB1/SETD2/TLR8	10
BP	GO:0052312	modulation of transcription in other organism involved in symbiotic interaction	10/2619	28/18670	0.0034	0.02857	0.02143	CCL5/CHD1/RRP1B/LEF1/CTDP1/PSMC3/HDAC1/TARDBP/EP300/HMGA2	10
BP	GO:0043255	regulation of carbohydrate biosynthetic process	24/2619	97/18670	0.003401	0.02857	0.02143	SIK1/PDK2/ENPP1/SNCA/PTH1R/EGF/GSK3B/INSR/DYRK2/RANBP2/GPER1/FAM3A/PTPN2/NFKB1/IGF1/PDGFB/OGT/HAS2/KAT2B/EP300/CRY1/PTK2B/PASK/SORBS1	24
BP	GO:1902882	regulation of response to oxidative stress	24/2619	97/18670	0.003401	0.02857	0.02143	GCH1/FBXW7/FBLN5/ACOX2/SLC7A11/HGF/NME5/MCTP1/PINK1/MAPK7/NOL3/GPX1/HSPB1/TRAP1/FUT8/SFPQ/MCL1/SOD1/HIF1A/VNN1/PYCR1/SESN1/ATF4/PSAP	24
BP	GO:0070374	positive regulation of ERK1 and ERK2 cascade	45/2619	215/18670	0.003474	0.02901	0.02176	NOTCH1/TREM2/CCL5/PRKD2/RASGRP1/FBXW7/MAPK3/RIPK2/ANGPT1/CCL18/SLAMF1/CFLAR/PTPRC/GPR183/EGFR/TNFRSF11A/APOE/KIT/BMP4/FGF20/HTR2B/PTPN22/PHB/GPER1/ARRB1/CD44/F2R/NTRK1/CCL8/FGF18/KDR/PDGFB/XCL1/MFHAS1/HMGB1/CALCR/CCR7/NOD2/CCL13/CIB1/NOD1/CCL7/ERBB4/PTK2B/RAP1B	45
BP	GO:0032675	regulation of interleukin-6 production	34/2619	152/18670	0.003476	0.02901	0.02176	TNFAIP3/IRAK3/TREM2/CD200/IL27RA/RIPK2/SLAMF1/SYT11/LILRB2/HGF/LILRA2/ARHGEF2/PTPN22/IL1RL2/ARRB1/F2R/IL6/GHSR/EREG/TYROBP/TNFSF4/HMGB1/NOD2/MAPKAPK2/LPL/IL17RC/IL1RN/NOD1/IL6R/XBP1/MYD88/TLR8/CEBPB/TWIST1	34
BP	GO:0007099	centriole replication	12/2619	37/18670	0.003481	0.02901	0.02176	CETN2/CEP135/MDM1/C2CD3/PLK2/CHMP2A/KIAA0753/ALMS1/KAT2B/CEP63/SPICE1/NUP62	12
BP	GO:0030212	hyaluronan metabolic process	12/2619	37/18670	0.003481	0.02901	0.02176	GUSB/IL15/HGF/EGF/PIM1/ITIH4/HMMR/CD44/NFKB1/HEXA/PDGFB/HAS2	12
BP	GO:0033280	response to vitamin D	12/2619	37/18670	0.003481	0.02901	0.02176	SFRP1/CXCL10/PTN/IL15/PIM1/STC1/PENK/MED1/TRIM24/KANK2/STC2/ATP2B1	12
BP	GO:0038083	peptidyl-tyrosine autophosphorylation	12/2619	37/18670	0.003481	0.02901	0.02176	MAPK3/ITK/EGFR/INSR/FGR/NTRK1/LCK/KDR/TXK/VEGFA/TNK1/PTK2B	12
BP	GO:1903902	positive regulation of viral life cycle	17/2619	61/18670	0.003492	0.02903	0.02178	NOTCH1/SRPK1/CCL5/ADAR/KPNA2/PC/CD28/TRIM21/CHMP2A/YTHDC2/TOP2A/PPIE/PPIB/NR5A2/VAPA/STAU1/PPIH	17
BP	GO:0018394	peptidyl-lysine acetylation	37/2619	169/18670	0.003492	0.02903	0.02178	BAZ1A/MAPK3/SNCA/NCOA3/CHEK1/NAP1L2/TADA3/MSL3/SET/BLOC1S1/LEF1/SETD5/ZNF451/EID1/MSL2/ARRB1/AUTS2/TAF10/BRPF1/TRRAP/NAA50/ELP3/BRCA2/TAF9B/TAF7/RUVBL2/KAT6A/KAT5/YEATS2/OGT/PRKAA1/KAT2B/ATF2/EP300/PIWIL2/MORF4L1/TWIST1	37
BP	GO:0018209	peptidyl-serine modification	63/2619	322/18670	0.003508	0.02912	0.02184	CDC7/NDNF/PRKD2/MAPK3/RIPK2/TBK1/ANGPT1/SNCA/PRKCB/ATR/CHEK2/HGF/DDIT4/ATM/DYRK4/EGFR/PFN2/NCK2/PINK1/PRKCH/NTRK2/PRKX/GSK3B/NTF3/MAPK7/DYRK2/ROCK1/MAP4K1/ARRB1/CD44/IFNG/PLK2/CHUK/PRKCI/CCNB1/IL6/VRK2/TOP1/PDGFB/CSNK1A1/AURKB/GALNT3/VEGFA/CALCR/PRKCQ/CSNK1E/NLK/MAPKAPK2/CAMK1/MKNK2/SPOCK2/AKAP9/PRKAA1/ATP2B4/RAF1/CDK1/PAK2/GGNBP2/CAPRIN2/MARK3/CLK1/HMGA2/PIK3CA	63
BP	GO:0097530	granulocyte migration	32/2619	141/18670	0.003554	0.02943	0.02207	SLAMF8/CXCL9/DYSF/CXCL10/CCL5/MAPK3/CXCL13/THBS4/CCL18/CXCL11/PECAM1/CXCL2/PTGER4/CCL8/RAC2/IRAK4/XCL1/CCR7/CXCL3/CXCR2/SCG2/CCL13/IL17RC/IL1RN/PIK3CD/MPP1/S100A12/LGALS3/CXADR/CCL7/CXCL8/IL17RA	32
BP	GO:1904894	positive regulation of STAT cascade	23/2619	92/18670	0.003555	0.02943	0.02207	AKR1B1/NOTCH1/JAK2/CCL5/CRLF1/IL15/IL7R/SOCS1/PECAM1/KIT/CTF1/CD40/F2R/IFNG/AGT/IGF1/CRLF3/IL6/ARL2BP/IL6R/GHR/ERBB4/PTK2B	23
BP	GO:0045765	regulation of angiogenesis	73/2619	383/18670	0.003559	0.02943	0.02207	TNFAIP3/SFRP1/CXCL10/PTN/NOTCH1/SPHK1/STAT1/PRKD2/FBXW7/CXCL13/PGF/THBS4/DDAH1/HLA-G/PRKCB/SEMA4A/FOXC1/HGF/ITGAX/ITGA5/CX3CR1/SERPINE1/ANGPT2/MAPK7/HSPB6/ERBB2/JAK1/TNMD/CMA1/PPARG/ROCK1/PPP1R16B/CD40/CXCR4/TIE1/HSPB1/KRIT1/CDH5/PLK2/AGT/NOS3/FGF18/S100A1/KDR/IL6/GHSR/PML/MTDH/VEGFA/PLXND1/CXCR2/SEMA3E/MAP3K3/HIF1A/HOXA5/EMP2/CIB1/NGFR/THBS2/KRT1/FKBPL/ATF2/XBP1/FOXJ2/CXCL8/PTK2B/COL4A2/CCR2/GPR4/SERPINF1/HMGA2/TWIST1/VEGFB	73
BP	GO:0032392	DNA geometric change	28/2619	119/18670	0.003594	0.02968	0.02226	CETN2/SETX/CHD1/CHD8/HNRNPA2B1/NBN/RECQL/DNA2/RPA1/DDX11/GINS1/ASCC3/HMGB3/ATRX/UBB/HMGB1/RAD50/TOP2A/DDB2/CHD3/RUVBL2/WRN/DDX1/ERCC2/MNAT1/GTF2H3/RFC2/HMGA1	28
BP	GO:0060541	respiratory system development	42/2619	198/18670	0.003609	0.02976	0.02232	SIX1/PTN/NOTCH1/CEBPA/SMCHD1/SOX9/CRISPLD2/IGFBP5/FBXW7/MAPK3/SLC7A11/RBP4/EGFR/LTBP3/ADA/BMP4/WNT11/ADAMTSL2/RCN3/LEF1/LAMA5/JMJD6/RC3H2/FOXF1/TNS3/ZFPM2/ASS1/NOS3/FGF18/TBX5/RBPJ/VEGFA/ALDH1A3/LIPA/DHCR7/AIMP2/HOXA5/TIMELESS/SIM2/CREB1/EP300/KRAS	42
BP	GO:0002092	positive regulation of receptor internalization	9/2619	24/18670	0.003698	0.0303	0.02273	PLCG2/ANGPT1/EGF/NTF3/MAGI2/SELE/ARRB1/CD63/VEGFA	9
BP	GO:0002407	dendritic cell chemotaxis	9/2619	24/18670	0.003698	0.0303	0.02273	SLAMF8/CCL5/GPR183/CCR5/CXCR4/HMGB1/CCR7/CXCR2/CCR2	9
BP	GO:0033081	regulation of T cell differentiation in thymus	9/2619	24/18670	0.003698	0.0303	0.02273	RASGRP1/IL7R/SOS1/ADA/BMP4/ERBB2/PTPN2/SOD1/VNN1	9
BP	GO:0071677	positive regulation of mononuclear cell migration	9/2619	24/18670	0.003698	0.0303	0.02273	CXCL10/LGMN/CCL5/SERPINE1/CREB3/PLA2G7/HMGB1/LGALS3/CCR2	9
BP	GO:2001026	regulation of endothelial cell chemotaxis	9/2619	24/18670	0.003698	0.0303	0.02273	NOTCH1/LGMN/PRKD2/CXCL13/HSPB1/FGF18/KDR/VEGFA/P2RX4	9
BP	GO:0043524	negative regulation of neuron apoptotic process	33/2619	147/18670	0.003722	0.0304	0.0228	SIX1/LGMN/NDNF/JAK2/CRLF1/ANGPT1/SNCA/TOX3/PINK1/CX3CR1/NTRK2/APOE/NTF3/SET/GDF5/FGF20/ROCK1/ARRB1/F2R/NTRK1/PRKCI/EN1/AXL/PIN1/NAIP/SOD1/HIF1A/TYRO3/KRAS/PTK2B/CEBPB/BDNF/PIK3CA	33
BP	GO:0007229	integrin-mediated signaling pathway	25/2619	103/18670	0.003725	0.0304	0.0228	PTN/ITGBL1/ITGAX/ITGAL/ITGA5/ITGAE/NEDD9/ITGB7/FGR/LAMA5/FERMT2/CD63/TYROBP/FUT8/FERMT1/LAT/PHACTR4/EMP2/ITGB5/TIMP1/COL3A1/FLNA/PLP1/PTK2B/TSPAN32	25
BP	GO:1905269	positive regulation of chromatin organization	25/2619	103/18670	0.003725	0.0304	0.0228	MTF2/JARID2/PRKD2/MAPK3/NIPBL/WDR61/DNMT1/ATM/ATF7IP/NAP1L2/PINK1/SART3/TPR/ING2/ARRB1/AUTS2/CCNB1/VEGFA/EED/PAXBP1/RUVBL2/AKAP8/OGT/PIWIL2/CDK9	25
BP	GO:0002475	antigen processing and presentation via MHC class Ib	7/2619	16/18670	0.003791	0.03063	0.02297	HLA-C/HLA-F/HLA-G/HLA-A/HLA-B/HLA-E/TAP2	7
BP	GO:0002643	regulation of tolerance induction	7/2619	16/18670	0.003791	0.03063	0.02297	IRAK3/HLA-G/LILRB2/IDO1/CD3E/HMGB1/PHLPP1	7
BP	GO:0002830	positive regulation of type 2 immune response	7/2619	16/18670	0.003791	0.03063	0.02297	IL4R/IDO1/CD81/IL6/XCL1/TNFSF4/NOD2	7
BP	GO:0006086	acetyl-CoA biosynthetic process from pyruvate	7/2619	16/18670	0.003791	0.03063	0.02297	PDK2/MPC2/GSTZ1/DLD/PDK1/PDHB/MPC1	7
BP	GO:0031958	corticosteroid receptor signaling pathway	7/2619	16/18670	0.003791	0.03063	0.02297	JAK2/NCOA6/PHB/ARID1A/YWHAH/LMO3/CRY1	7
BP	GO:0061548	ganglion development	7/2619	16/18670	0.003791	0.03063	0.02297	SIX1/UNC5C/SEMA3A/FZD3/RGS4/SEMA3F/INSM1	7
BP	GO:0072109	glomerular mesangium development	7/2619	16/18670	0.003791	0.03063	0.02297	NOTCH1/CFLAR/BMP4/EGR1/PDGFB/IL6R/GPR4	7
BP	GO:0006509	membrane protein ectodomain proteolysis	13/2619	42/18670	0.003796	0.03063	0.02297	TNFRSF1B/ADAM19/ADAM17/TIMP2/APOE/ROCK1/IFNG/PSENEN/TIMP4/PRKCQ/TIMP1/APH1A/LRIG2	13
BP	GO:0033048	negative regulation of mitotic sister chromatid segregation	13/2619	42/18670	0.003796	0.03063	0.02297	ATM/PTTG1/TPR/BUB1B/LCMT1/NDC80/CCNB1/CDC20/ATRX/AURKB/PTTG2/CENPF/FBXO5	13
BP	GO:0032869	cellular response to insulin stimulus	45/2619	216/18670	0.003805	0.03066	0.023	PTPRE/PDK2/STAT1/ENPP1/SH2B2/ATP6V0D1/GOT1/PRKCB/CFLAR/SOS1/PID1/BAIAP2/GSK3B/INSR/CDK4/SOCS1/IDE/OSBPL8/PPARG/PTPN2/TCIRG1/GRB10/MZB1/PHIP/WDTC1/AGT/PRKCI/RAB13/GHSR/PCK2/ATP6V0E2/PRKCQ/VAMP2/LPL/OGT/PRKAA1/KAT2B/CYFIP1/XBP1/INHBB/LPIN1/CISH/ATP2B1/PIK3CA/SORBS1	45
BP	GO:0046209	nitric oxide metabolic process	21/2619	82/18670	0.003842	0.03092	0.02319	GCH1/GCHFR/JAK2/CLU/SMAD3/DDAH1/RORA/CX3CR1/NQO1/INSR/DDAH2/IFNG/AGT/ASS1/TSPO/NOS3/CPS1/P2RX4/HBB/ATP2B4/PTK2B	21
BP	GO:0002577	regulation of antigen processing and presentation	8/2619	20/18670	0.00387	0.03098	0.02324	TREM2/LILRB2/HFE/HLA-DOB/SLC11A1/CCR7/NOD2/NOD1	8
BP	GO:0016137	glycoside metabolic process	8/2619	20/18670	0.00387	0.03098	0.02324	AKR1B1/FUCA1/AKR1B10/GUSB/AKR7A2/AKR1C3/AKR1C4/TH	8
BP	GO:0032816	positive regulation of natural killer cell activation	8/2619	20/18670	0.00387	0.03098	0.02324	RASGRP1/IL15/HLA-F/HLA-E/TOX/AXL/TYROBP/IL6R	8
BP	GO:0060008	Sertoli cell differentiation	8/2619	20/18670	0.00387	0.03098	0.02324	SOX9/SDC1/ARID4B/NTRK1/RAB13/ATRX/ARID4A/FLNA	8
BP	GO:0050729	positive regulation of inflammatory response	34/2619	153/18670	0.00388	0.03103	0.02327	NFKBIA/NUPR1/CEBPA/TREM2/JAK2/SNCA/CCL18/IL15/TNIP1/EGFR/IDO1/SERPINE1/TNFRSF11A/HLA-E/PLA2G7/CD28/PTGER4/CD81/AGT/ABCC1/VAMP7/IL6/IL17RB/TNFSF4/CCR7/NOD2/LPL/IL17RC/TAC1/S100A12/MYD88/CCR2/CEBPB/IL17RA	34
BP	GO:0048024	regulation of mRNA splicing, via spliceosome	24/2619	98/18670	0.003917	0.03128	0.02346	SRPK1/HNRNPA2B1/CIRBP/CELF2/MBNL3/KHDRBS3/SART3/PRDX6/FAM172A/CELF1/HNRNPK/JMJD6/RBM15/TIA1/SFSWAP/SRSF4/HNRNPA1/SRSF8/RBM19/SREK1/YTHDC1/DAZAP1/SON/NUP98	24
BP	GO:0006809	nitric oxide biosynthetic process	20/2619	77/18670	0.003966	0.03146	0.0236	GCH1/GCHFR/JAK2/CLU/SMAD3/DDAH1/RORA/CX3CR1/NQO1/INSR/DDAH2/IFNG/AGT/ASS1/TSPO/NOS3/P2RX4/HBB/ATP2B4/PTK2B	20
BP	GO:0035966	response to topologically incorrect protein	42/2619	199/18670	0.003968	0.03146	0.0236	SDF2/THBS4/CLU/ATP6V0D1/KLHDC3/HERPUD1/KDELR3/HSPH1/NCK2/YIF1A/ATF3/DNAJB14/CREB3/DDX11/DNAJA1/UBXN4/TATDN2/PTPN2/HSPB1/EXTL2/DAXX/MBTPS1/ATF6/ANKZF1/COMP/TBL2/HSPA6/HSPB2/EDEM1/OPTN/DNAJC3/ERP44/CXXC1/EP300/XBP1/HSPA2/CXCL8/ATF4/HSPA5/ASNS/STC2/DDIT3	42
BP	GO:0038127	ERBB signaling pathway	32/2619	142/18670	0.003984	0.03146	0.0236	EFEMP1/LGMN/SOX9/REPS2/FBXW7/BTC/SOS1/ADAM17/EGFR/EGF/NCK2/ERBB2/GPER1/PTPN2/CHMP6/CBLB/ARHGEF7/AGT/HBEGF/RBPJ/MYOC/EREG/PLCE1/MATK/RHBDF2/HIP1R/ERBB4/MVP/PTK2B/NUP62/PIK3CA/NCF1	32
BP	GO:0046467	membrane lipid biosynthetic process	32/2619	142/18670	0.003984	0.03146	0.0236	PIGT/GPAA1/SPHK1/GAL3ST4/PRKD2/PEMT/PIGK/PGAP2/CERS6/PIGA/PRKD3/PIGP/DPM3/ASAH1/CERS4/UGCG/ST3GAL2/CERS2/ALDH3A2/PIGH/SGMS1/PRKAA1/PIGZ/FA2H/SCCPDH/PIGC/ST8SIA2/PGAP3/SGPL1/VAPA/ALDH3B1/B4GALT3	32
BP	GO:0072006	nephron development	32/2619	142/18670	0.003984	0.03146	0.0236	SIX1/HOXA11/NOTCH1/STAT1/SOX9/PGF/ANGPT1/CFLAR/FOXC1/NUP160/CTNNBIP1/ANGPT2/PECAM1/BMP4/WNT11/MAGI2/KLHL3/LAMA5/ACAT1/AGT/SIX2/MYC/EGR1/PDGFB/VEGFA/PLCE1/MAGED1/IL6R/MPV17/SMO/GPR4/PODXL	32
BP	GO:0006986	response to unfolded protein	38/2619	176/18670	0.003988	0.03146	0.0236	THBS4/ATP6V0D1/KLHDC3/HERPUD1/KDELR3/HSPH1/NCK2/YIF1A/ATF3/CREB3/DDX11/DNAJA1/UBXN4/TATDN2/PTPN2/HSPB1/EXTL2/DAXX/MBTPS1/ATF6/COMP/TBL2/HSPA6/HSPB2/EDEM1/OPTN/DNAJC3/ERP44/CXXC1/EP300/XBP1/HSPA2/CXCL8/ATF4/HSPA5/ASNS/STC2/DDIT3	38
BP	GO:0030323	respiratory tube development	38/2619	176/18670	0.003988	0.03146	0.0236	PTN/NOTCH1/CEBPA/SOX9/CRISPLD2/IGFBP5/FBXW7/MAPK3/SLC7A11/RBP4/EGFR/LTBP3/ADA/HECA/BMP4/WNT11/ADAMTSL2/RCN3/LAMA5/JMJD6/RC3H2/FOXF1/TNS3/ZFPM2/NOS3/FGF18/TBX5/RBPJ/VEGFA/LIPA/DHCR7/AIMP2/HOXA5/TIMELESS/SIM2/CREB1/EP300/KRAS	38
BP	GO:0033028	myeloid cell apoptotic process	11/2619	33/18670	0.004003	0.03146	0.0236	CCL5/SLC7A11/ADAM17/CCR5/IRF3/PIK3CB/IL6/GHSR/NOD2/CXCR2/PIK3CD	11
BP	GO:0036003	positive regulation of transcription from RNA polymerase II promoter in response to stress	11/2619	33/18670	0.004003	0.03146	0.0236	NOTCH1/ATF3/MAPK7/ATF6/RBPJ/VEGFA/HIF1A/CEBPB/ATF4/HSPA5/DDIT3	11
BP	GO:1901186	positive regulation of ERBB signaling pathway	11/2619	33/18670	0.004003	0.03146	0.0236	FBXW7/SOS1/ADAM17/EGF/GPER1/AGT/RBPJ/EREG/HIP1R/NUP62/NCF1	11
BP	GO:1902692	regulation of neuroblast proliferation	11/2619	33/18670	0.004003	0.03146	0.0236	PTN/NOTCH1/ASPM/SMARCD3/CX3CR1/FZD3/VEGFA/DCT/HIF1A/SIX3/SMO	11
BP	GO:0002832	negative regulation of response to biotic stimulus	14/2619	47/18670	0.00401	0.03146	0.0236	TNFAIP3/RNF125/MICB/LILRA2/CARD8/HTRA1/TSPAN6/FAM3A/TRIB1/GPATCH3/PPM1B/PRDX2/SEC14L1/RIOK3	14
BP	GO:0006953	acute-phase response	14/2619	47/18670	0.00401	0.03146	0.0236	SERPINA3/SERPINA1/TNFRSF11A/ITIH4/HFE/F8/ASS1/IL6/APOL2/MBL2/IL6R/CEBPB/IL22/REG3A	14
BP	GO:0035722	interleukin-12-mediated signaling pathway	14/2619	47/18670	0.00401	0.03146	0.0236	LCP1/JAK2/HNRNPA2B1/TYK2/RALA/CAPZA1/JAK1/LMNB1/STAT4/IFNG/SOD1/PAK2/RAP1B/RPLP0	14
BP	GO:0045927	positive regulation of growth	54/2619	270/18670	0.004093	0.03208	0.02406	SFRP1/NOTCH1/SPHK1/DIO3/SEMA4D/NIPBL/MACF1/CD38/RFTN1/ADAM17/EGFR/ITSN2/PIM1/INSR/ERBB2/EFNA5/LEF1/USP47/BBS4/CXCR4/SYT17/FGFR1OP/ZFPM2/IGF1/TBX5/CCNB1/RND2/GHSR/HBEGF/TAF9B/RBPJ/VEGFA/PIN1/PSMD10/DNPH1/CIB1/GOLGA4/PPIB/TRPV2/CREB1/CDK1/CDKL5/GHR/SYT1/ERBB4/CYFIP1/TRIM32/RPS6KA1/PTK2B/DSCAM/SMO/CPNE6/BDNF/NEDD4L	54
BP	GO:0070372	regulation of ERK1 and ERK2 cascade	59/2619	300/18670	0.004104	0.03213	0.0241	GBP1/NOTCH1/TREM2/CCL5/PRKD2/BTN2A2/RASGRP1/FBXW7/MAPK3/RIPK2/ANGPT1/CCL18/SLAMF1/DUSP6/TNIP1/CFLAR/PTPRC/GPR183/EGFR/TNFRSF11A/APOE/PRMT5/ATF3/KIT/BMP4/FGF20/ERBB2/HTR2B/PTPN22/PHB/GPER1/PTPN2/ARRB1/CD44/F2R/NTRK1/CCL8/NDRG2/LMO3/SIRT3/FGF18/KDR/PDGFB/XCL1/MFHAS1/EIF3A/PIN1/HMGB1/CALCR/CCR7/NOD2/CCL13/CIB1/NOD1/CCL7/ERBB4/FBLN1/PTK2B/RAP1B	59
BP	GO:1990089	response to nerve growth factor	15/2619	52/18670	0.004137	0.03234	0.02426	MICALL1/PTN/STMN2/NTRK2/NTF3/MAGI2/NTRK1/ACAP2/SORT1/USP8/TAC1/CIB1/CREB1/HSPA5/BDNF	15
BP	GO:0071241	cellular response to inorganic substance	45/2619	217/18670	0.004163	0.03251	0.02438	CEBPA/LGMN/ECT2/MAPK3/SNCA/ALOX5AP/CCNA2/SYT11/CFLAR/BAD/EGFR/PRNP/NQO1/HFE/DDX11/KCNK3/ANK3/GUCA1A/SYT17/DAXX/CRHBP/CHUK/TSPO/CCNB1/AKR1C3/ADCY1/ATRX/P2RX4/NFE2L1/SOD1/TIMELESS/AQP2/MCOLN1/PRKAA1/CREB1/ID2/SYT1/RASGRP2/HNRNPD/ATF4/SERPINF1/HSPA5/CPNE6/TH/NCF1	45
BP	GO:0001755	neural crest cell migration	16/2619	57/18670	0.004194	0.03263	0.02447	FOLR1/SEMA4D/SEMA4A/SEMA3A/BMP4/SEMA4C/HTR2B/LAMA5/SEMA3F/EFNB1/SEMA3E/PHACTR4/HIF1A/ERBB4/SMO/TWIST1	16
BP	GO:0071398	cellular response to fatty acid	16/2619	57/18670	0.004194	0.03263	0.02447	SFRP1/PID1/CDK4/PPARG/PTGER4/PTGFR/ASS1/CCNB1/AKR1C3/CPS1/TNFSF4/LPL/AKAP8/PRKAA1/CREB1/ID3	16
BP	GO:0045453	bone resorption	17/2619	62/18670	0.004195	0.03263	0.02447	TNFAIP3/TNFRSF11B/TFRC/CD38/PTH1R/EGFR/LTBP3/TNFRSF11A/TCIRG1/S1PR1/ADRB2/RAC2/IL6/CA2/SNX10/NCDN/PTK2B	17
BP	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	25/2619	104/18670	0.004264	0.03309	0.02482	NUPR1/TNFRSF1B/CLU/BCL2A1/CHEK2/DDIT4/ATM/BAD/ING2/DYRK2/HNRNPK/USP47/CD44/BRCA2/TAF9B/PML/CASP9/MCL1/CIDEB/IFI16/BCL2L2/RAD9A/CDKN1A/EP300/TRIM32	25
BP	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	25/2619	104/18670	0.004264	0.03309	0.02482	TNFAIP3/EYA2/AR/FAS/CFLAR/HGF/SERPINE1/MAPK7/BMP4/NOL3/ARHGEF2/PEA15/GPX1/PHIP/IGF1/NOS3/SCG2/MCL1/FAIM/PRDX2/CTTN/RAF1/TCF7L2/LGALS3/RNF34	25
BP	GO:1903725	regulation of phospholipid metabolic process	22/2619	88/18670	0.004297	0.0333	0.02498	SOCS6/MTMR4/MTMR9/SOCS1/KIT/HTR2B/FGR/TAZ/CD81/APOC1/DGKZ/PIK3R5/PDGFB/CD19/MTMR1/CCR7/NOD2/WDR91/FABP3/PTK2B/STOML2/CISH	22
BP	GO:0007265	Ras protein signal transduction	83/2619	448/18670	0.004396	0.03403	0.02552	NOTCH1/JAK2/ECT2/RASGRP1/SH2B2/STK19/CCNA2/RAB27A/ARHGEF3/DNMT1/CDC42EP3/SOS1/ARHGEF40/ITSN2/ARHGEF9/CDC42SE1/TIMP2/RAP2C/APOE/RASGRP3/RALA/PECAM1/RAB40B/DENND4B/MADD/RHOF/ARHGEF2/ROCK1/SHOC2/PLD1/ARRB1/F2R/NTRK1/AUTS2/FOXM1/PLK2/ARHGEF7/MAPK11/CHUK/IGF1/RAB13/RAC2/RAPGEF6/RASIP1/MAP4K4/RND2/RALGDS/MYOC/USP8/ARHGAP35/PLCE1/DHCR24/KPNB1/NET1/LAT/PHACTR4/OGT/RANGRF/NGFR/RAF1/TNK1/AKAP13/RAB20/RAB11B/RHOH/EPS8L2/IFT22/CDKN1A/RALGPS2/MAPRE2/CYFIP1/RASGRP2/COL3A1/RAB15/KRAS/RAP1B/GPR4/ARFGEF1/KANK2/MCF2L/NUP62/EPOR/NRAS	83
BP	GO:0002707	negative regulation of lymphocyte mediated immunity	12/2619	38/18670	0.004448	0.03435	0.02576	PARP3/HLA-F/HLA-G/IL7R/PTPRC/THOC1/HLA-E/HFE/CD96/CR1/XCL1/C4BPB	12
BP	GO:0097064	ncRNA export from nucleus	12/2619	38/18670	0.004448	0.03435	0.02576	NUP160/NUP153/TPR/NUP50/SEC13/RANBP2/NUP210/NUP43/NDC1/NCBP2/NUP98/NUP62	12
BP	GO:0048145	regulation of fibroblast proliferation	21/2619	83/18670	0.004477	0.03453	0.0259	SFRP1/NUPR1/SPHK1/CCNA2/NDUFS4/BTC/EGFR/CDK4/PPARG/PEX2/AGT/IGF1/CCNB1/B4GALT7/MYC/PML/EREG/PDGFB/CREB1/CDKN1A/TRIM32	21
BP	GO:0006888	ER to Golgi vesicle-mediated transport	44/2619	212/18670	0.004493	0.0346	0.02595	COPZ2/FOLR1/GAS1/PROS1/SEC24A/TMED1/KDELR3/SERPINA1/YIF1A/DCTN6/TMED3/DCTN3/PPP6R3/CAPZA1/LMAN2/SEC22B/VTI1B/ANK3/SEC13/F8/ERGIC3/DCTN2/TRAPPC2L/CNIH1/TRAPPC10/YIPF5/DYNC1I1/TEX261/SEC16A/VAMP7/TRAPPC8/DYNC1H1/TMED2/GOLGB1/SPAST/TMED9/TMED10/RANGRF/ANKRD28/VAPA/NAPA/TRAPPC11/LMF1/CD59	44
BP	GO:0048525	negative regulation of viral process	24/2619	99/18670	0.004498	0.0346	0.02595	SRPK1/STAT1/CCL5/FAM111A/SLPI/TNIP1/APOBEC3C/TRIM26/ZC3HAV1/ISG20/CCL8/BANF1/TRIM21/PML/IFITM2/MBL2/CCNK/HDAC1/IFI16/TARDBP/FCN1/TRIM32/VAPA/HMGA2	24
BP	GO:0070229	negative regulation of lymphocyte apoptotic process	10/2619	29/18670	0.004546	0.03493	0.0262	CCL5/IL7R/IDO1/ADA/BMP4/CD27/AURKB/PRKCQ/HIF1A/BCL10	10
BP	GO:0042177	negative regulation of protein catabolic process	30/2619	132/18670	0.004556	0.03497	0.02623	DYSF/NELL1/IRAK3/MYCBP2/SNCA/LAMP3/SMAD3/GABARAPL2/ATRAID/CTSA/EGFR/UBE2J1/TIMP2/HFE/ROCK1/FHIT/PHB/PML/EPHA4/PIN1/TIMP4/OGT/BANP/RYBP/TIMP1/N4BP1/FLNA/CLEC16A/LRIG2/USP14	30
BP	GO:0006475	internal protein amino acid acetylation	36/2619	166/18670	0.004616	0.03538	0.02654	BAZ1A/MAPK3/SNCA/NCOA3/CHEK1/NAP1L2/TADA3/MSL3/SET/LEF1/SETD5/ZNF451/EID1/MSL2/ARRB1/AUTS2/TAF10/MDH2/BRPF1/TRRAP/NAA50/ELP3/BRCA2/TAF9B/TAF7/RUVBL2/KAT6A/KAT5/YEATS2/OGT/KAT2B/ATF2/EP300/PIWIL2/MORF4L1/TWIST1	36
BP	GO:0070664	negative regulation of leukocyte proliferation	20/2619	78/18670	0.004645	0.03556	0.02667	TNFAIP3/BTN2A2/HLA-G/PLA2G2D/LILRB2/ATM/TNFRSF21/CTLA4/IDO1/PRNP/TNFRSF14/BMP4/ERBB2/PELI1/CCL8/TYROBP/XCL1/GLMN/GAL/CEBPB	20
BP	GO:0043543	protein acylation	50/2619	248/18670	0.004738	0.03623	0.02717	BAZ1A/NUPR1/SPHK1/ZDHHC18/MAPK3/SNCA/NCOA3/CHEK1/ZDHHC4/NAP1L2/ZDHHC17/TADA3/GSK3B/MSL3/SET/BLOC1S1/LEF1/SETD5/ZNF451/EID1/MSL2/ARRB1/AUTS2/TAF10/MDH2/NAA16/BRPF1/DLD/TRRAP/NAA50/TAOK1/ELP3/BRCA2/TAF9B/TAF7/ZDHHC3/RUVBL2/KAT6A/PPM1B/KAT5/CAMK1/YEATS2/OGT/PRKAA1/KAT2B/ATF2/EP300/PIWIL2/MORF4L1/TWIST1	50
BP	GO:0030324	lung development	37/2619	172/18670	0.004745	0.03624	0.02718	PTN/NOTCH1/CEBPA/SOX9/CRISPLD2/IGFBP5/FBXW7/MAPK3/SLC7A11/RBP4/EGFR/LTBP3/ADA/BMP4/WNT11/ADAMTSL2/RCN3/LAMA5/JMJD6/RC3H2/FOXF1/TNS3/ZFPM2/NOS3/FGF18/TBX5/RBPJ/VEGFA/LIPA/DHCR7/AIMP2/HOXA5/TIMELESS/SIM2/CREB1/EP300/KRAS	37
BP	GO:0072503	cellular divalent inorganic cation homeostasis	90/2619	493/18670	0.004755	0.03627	0.0272	CXCL9/RMDN3/CXCL10/ATP1B1/JAK2/CCL5/FIS1/ATP2A3/PLCG2/CXCL13/SNCA/SRI/ATP13A3/SMAD3/HERPUD1/CXCL11/GOT1/EPHX2/PRKCB/PTPRC/CD38/PTH1R/ATP2C1/PRNP/CX3CR1/STC1/APOE/CCR5/NOL3/HTR2B/GNG3/KCNK3/CD40/PTGER4/GPER1/CXCR4/PTGFR/TCIRG1/S1PR1/ELANE/F2R/TMCO1/CCL8/CDH5/LCK/ITPR2/MCOLN3/SLC39A8/ATP2B2/AGT/PIK3CB/HCRT/HCRTR2/PML/FAM155A/XCL1/SLC11A1/CD19/P2RX4/HMGB1/CALCR/PLCE1/CCR7/CXCR2/MICU1/CCL13/CACNB2/SLC39A14/NMB/LIME1/CALB2/TPCN1/MCOLN1/LPAR2/ANXA7/TAC1/ATP2B4/CACNA1D/CCL7/MS4A1/PTK2B/CCR2/ATF4/STOML2/GPR4/LETM1/STC2/ATP2B1/DDIT3/CXCR6	90
BP	GO:0000281	mitotic cytokinesis	19/2619	73/18670	0.004795	0.03636	0.02727	ECT2/ARL3/RACGAP1/NUSAP1/CEP55/ROCK1/ANK3/BBS4/CHMP6/CHMP2A/KIF4A/BRCA2/USP8/SPAST/CHMP1B/SON/KIF20A/MYH10/NUP62	19
BP	GO:0002312	B cell activation involved in immune response	19/2619	73/18670	0.004795	0.03636	0.02727	PARP3/TFRC/IL27RA/PLCG2/ERCC1/NBN/PTPRC/GPR183/DOCK10/ADA/THOC1/CD28/CD40/CD19/TNFSF4/BATF/XBP1/PTK2B/CD40LG	19
BP	GO:0046128	purine ribonucleoside metabolic process	19/2619	73/18670	0.004795	0.03636	0.02727	NME4/NME7/GAMT/PEMT/IMPDH2/NT5C2/NME5/ADK/ADA/MOCS2/DGUOK/NME3/PNP/GUK1/AHCY/MPP1/TJP2/NT5E/AMPD3	19
BP	GO:0050688	regulation of defense response to virus	19/2619	73/18670	0.004795	0.03636	0.02727	TNFAIP3/AIM2/RNF125/STAT1/BIRC3/IL15/MICB/PUM2/BIRC2/HTRA1/TSPAN6/GPATCH3/MMP12/TRAF3/PPM1B/DDX60/SEC14L1/RIOK3/TSPAN32	19
BP	GO:1901983	regulation of protein acetylation	19/2619	73/18670	0.004795	0.03636	0.02727	MAPK3/SNCA/CHEK1/NAP1L2/GSK3B/SET/SETD5/ZNF451/EID1/ARRB1/AUTS2/TAOK1/TAF7/RUVBL2/KAT5/CAMK1/PRKAA1/PIWIL2/TWIST1	19
BP	GO:0008593	regulation of Notch signaling pathway	25/2619	105/18670	0.004867	0.03686	0.02765	NFKBIA/NOTCH1/GALNT11/FBXW7/TSPAN15/EGFR/EGF/NOTCH4/KIT/RFNG/GDPD5/ARRB1/MAML1/POSTN/POFUT1/PRKCI/NOS3/DLK1/RBPJ/LLGL2/NOD2/RITA1/JAG2/KAT2B/EP300	25
BP	GO:0033047	regulation of mitotic sister chromatid segregation	18/2619	68/18670	0.00492	0.03712	0.02784	NIPBL/ATM/DLGAP5/PTTG1/TPR/BUB1B/LCMT1/SMC5/NDC80/CENPE/CCNB1/CDC20/ATRX/AURKB/TACC3/PTTG2/CENPF/FBXO5	18
BP	GO:0050918	positive chemotaxis	18/2619	68/18670	0.00492	0.03712	0.02784	CXCL10/CCL5/PGF/ANGPT1/SMAD3/HGF/ANGPT2/NTF3/BMP4/S1PR1/KDR/PDGFB/VEGFA/HMGB1/SCG2/LGALS3/CXCL8/VEGFB	18
BP	GO:0071230	cellular response to amino acid stimulus	18/2619	68/18670	0.00492	0.03712	0.02784	SIX1/DNMT1/UBR2/EGFR/BAIAP2/NTRK2/SOCS1/RRAGA/ASS1/LAMTOR2/RRAGD/COL4A1/XBP1/COL3A1/SESN1/HNRNPD/CEBPB/BCL11A	18
BP	GO:0018393	internal peptidyl-lysine acetylation	35/2619	161/18670	0.004965	0.03735	0.02801	BAZ1A/MAPK3/SNCA/NCOA3/CHEK1/NAP1L2/TADA3/MSL3/SET/LEF1/SETD5/ZNF451/EID1/MSL2/ARRB1/AUTS2/TAF10/BRPF1/TRRAP/NAA50/ELP3/BRCA2/TAF9B/TAF7/RUVBL2/KAT6A/KAT5/YEATS2/OGT/KAT2B/ATF2/EP300/PIWIL2/MORF4L1/TWIST1	35
BP	GO:0032635	interleukin-6 production	35/2619	161/18670	0.004965	0.03735	0.02801	TNFAIP3/IRAK3/TREM2/CD200/IL27RA/RIPK2/SLAMF1/SYT11/LILRB2/HGF/LILRA2/ARHGEF2/PTPN22/IL1RL2/ARRB1/F2R/IL6/GHSR/EREG/TYROBP/TNFSF4/HMGB1/NOD2/MAPKAPK2/LPL/IL17RC/IL1RN/NOD1/IL6R/BCL10/XBP1/MYD88/TLR8/CEBPB/TWIST1	35
BP	GO:0046427	positive regulation of JAK-STAT cascade	22/2619	89/18670	0.004968	0.03735	0.02801	AKR1B1/NOTCH1/JAK2/CCL5/CRLF1/IL15/SOCS1/PECAM1/KIT/CTF1/CD40/F2R/IFNG/AGT/IGF1/CRLF3/IL6/ARL2BP/IL6R/GHR/ERBB4/PTK2B	22
BP	GO:0002637	regulation of immunoglobulin production	17/2619	63/18670	0.005009	0.03762	0.02821	PARP3/TFRC/IL27RA/IL4R/PTPRC/RBP4/THOC1/HLA-E/CD28/CD40/MZB1/IL6/XCL1/TNFSF4/XBP1/IL13RA2/CD40LG	17
BP	GO:0045840	positive regulation of mitotic nuclear division	15/2619	53/18670	0.005036	0.03762	0.02821	SPHK1/NIPBL/BTC/DLGAP5/EGF/INSR/NUSAP1/CD28/SMC5/PHIP/LRP5/IGF1/EREG/PDGFB/NUP62	15
BP	GO:0031663	lipopolysaccharide-mediated signaling pathway	16/2619	58/18670	0.005053	0.03762	0.02821	TNFAIP3/NFKBIA/CCL5/MAPK3/RIPK2/MALT1/LILRA2/CARD8/IRF3/PTPN22/TRIB1/NOS3/MTDH/LY86/PRDX2/BCL10	16
BP	GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors	16/2619	58/18670	0.005053	0.03762	0.02821	TNFAIP3/SFRP1/FAS/CFLAR/HGF/SERPINE1/ATF3/MADD/ARHGEF2/PEA15/GPX1/NOS3/FAIM/RAF1/LGALS3/RNF34	16
BP	GO:0071375	cellular response to peptide hormone stimulus	62/2619	321/18670	0.005055	0.03762	0.02821	PTPRE/PDK2/STAT1/JAK2/ENPP1/SH2B2/PRKAR2A/ATP6V0D1/GOT1/CCNA2/PRKCB/CFLAR/SOS1/PID1/BAIAP2/GSK3B/INSR/CDK4/SOCS1/CYP11A1/IDE/OSBPL8/PPARG/ROCK1/GPER1/PTPN2/TCIRG1/NFKB1/GRB10/MZB1/PHIP/WDTC1/AGT/ASS1/CRHBP/PRKCI/RAB13/GHSR/ADCY1/CPS1/PCK2/CA2/ATP6V0E2/PRKCQ/VAMP2/LPL/OGT/PRKAA1/ADCY2/CREB1/STAT5A/GHR/KAT2B/CYFIP1/XBP1/INHBB/RAP1B/LPIN1/CISH/ATP2B1/PIK3CA/SORBS1	62
BP	GO:0000729	DNA double-strand break processing	9/2619	25/18670	0.005069	0.03762	0.02821	NBN/ATM/BARD1/DNA2/RNF138/SETMAR/RAD50/KAT5/WDR70	9
BP	GO:0002335	mature B cell differentiation	9/2619	25/18670	0.005069	0.03762	0.02821	SLAMF8/PLCG2/MALT1/GPR183/DOCK10/ADA/CD19/XBP1/PTK2B	9
BP	GO:0002507	tolerance induction	9/2619	25/18670	0.005069	0.03762	0.02821	TNFAIP3/IRAK3/HLA-G/LILRB2/IDO1/HLA-E/CD3E/HMGB1/PHLPP1	9
BP	GO:0021680	cerebellar Purkinje cell layer development	9/2619	25/18670	0.005069	0.03762	0.02821	RORA/B4GALT2/AGTPBP1/HERC1/NAGLU/UQCRQ/SEZ6L/HSPA5/MYH10	9
BP	GO:0048103	somatic stem cell division	9/2619	25/18670	0.005069	0.03762	0.02821	NOTCH1/ASPM/FGF13/KIT/ARHGEF2/LEF1/ZFP36L2/DCT/FZD7	9
BP	GO:0050927	positive regulation of positive chemotaxis	9/2619	25/18670	0.005069	0.03762	0.02821	PGF/SMAD3/NTF3/S1PR1/KDR/VEGFA/SCG2/CXCL8/VEGFB	9
BP	GO:0008203	cholesterol metabolic process	33/2619	150/18670	0.005166	0.03812	0.02859	CEBPA/LIPC/LBR/CH25H/PMVK/EPHX2/ERLIN2/APOL1/APOE/FDX1/CYP11A1/RXRA/CYP7B1/SNX17/SC5D/CAT/CLN6/APOC1/MBTPS1/APOL2/DHCR24/DHCR7/KPNB1/NFE2L1/SOD1/PRKAA1/CYB5R3/ACAA2/LIMA1/NPC1/NFYC/LMF1/MVK	33
BP	GO:0006409	tRNA export from nucleus	11/2619	34/18670	0.00518	0.03812	0.02859	NUP160/NUP153/TPR/NUP50/SEC13/RANBP2/NUP210/NUP43/NDC1/NUP98/NUP62	11
BP	GO:0043368	positive T cell selection	11/2619	34/18670	0.00518	0.03812	0.02859	PTPRC/BCL11B/PTPN2/ZAP70/CD3E/LY9/CD3D/IL6/BATF/CYLD/CD3G	11
BP	GO:0045066	regulatory T cell differentiation	11/2619	34/18670	0.00518	0.03812	0.02859	IRF1/BTN2A2/HLA-G/PLA2G2D/LILRB2/CTLA4/SOCS1/CD28/CR1/IFNG/TNFSF4	11
BP	GO:0070050	neuron cellular homeostasis	11/2619	34/18670	0.00518	0.03812	0.02859	FGGY/HAAO/ATP2B2/TAOK1/IL6/CACNB2/CALB2/PRKAA1/CACNA1D/TYRO3/ATP2B1	11
BP	GO:0070670	response to interleukin-4	11/2619	34/18670	0.00518	0.03812	0.02859	IL2RG/IL4R/TCF7/IMPDH2/CDK4/LEF1/PTPN2/PML/XCL1/XBP1/HSPA5	11
BP	GO:0071431	tRNA-containing ribonucleoprotein complex export from nucleus	11/2619	34/18670	0.00518	0.03812	0.02859	NUP160/NUP153/TPR/NUP50/SEC13/RANBP2/NUP210/NUP43/NDC1/NUP98/NUP62	11
BP	GO:0048144	fibroblast proliferation	21/2619	84/18670	0.005197	0.03821	0.02866	SFRP1/NUPR1/SPHK1/CCNA2/NDUFS4/BTC/EGFR/CDK4/PPARG/PEX2/AGT/IGF1/CCNB1/B4GALT7/MYC/PML/EREG/PDGFB/CREB1/CDKN1A/TRIM32	21
BP	GO:0072676	lymphocyte migration	26/2619	111/18670	0.005216	0.03826	0.0287	CXCL10/CD200/CCL5/IL27RA/CXCL13/CH25H/CCL18/CXCL11/STK10/GPR183/ADAM17/TNFRSF14/CYP7B1/ITGB7/S1PR1/ZAP70/CCL8/XCL1/CCR7/CCL13/PADI2/PIK3CD/TNFSF14/CCL7/PTK2B/CCR2	26
BP	GO:1904019	epithelial cell apoptotic process	26/2619	111/18670	0.005216	0.03826	0.0287	TNFAIP3/NUPR1/NDNF/MAP3K5/JAK2/ANGPT1/HLA-G/TNIP2/CFLAR/BAD/SERPINE1/MAPK7/CD40/GPER1/KRIT1/TIA1/PRKCI/KDR/IL6/AKR1C3/SORT1/SCG2/JAG2/SIX3/TCF7L2/CD40LG	26
BP	GO:1901215	negative regulation of neuron death	43/2619	208/18670	0.005302	0.03883	0.02912	SIX1/LGMN/NDNF/CD200/TNFRSF1B/JAK2/CRLF1/ANGPT1/SNCA/HLA-F/TOX3/SLC7A11/REL/PINK1/CX3CR1/NTRK2/APOE/GSK3B/NTF3/SET/GDF5/FGF20/ROCK1/ARRB1/F2R/NTRK1/PRKCI/EN1/AXL/PIN1/NAIP/SOD1/HIF1A/IKBKG/CREB1/TYRO3/KRAS/PTK2B/CEBPB/ATF4/SERPINF1/BDNF/PIK3CA	43
BP	GO:0000722	telomere maintenance via recombination	6/2619	13/18670	0.005362	0.03883	0.02912	SMC6/ERCC1/SMC5/BRCA2/RAD51C/RAD50	6
BP	GO:0009162	deoxyribonucleoside monophosphate metabolic process	6/2619	13/18670	0.005362	0.03883	0.02912	TK2/DGUOK/GUK1/DCTD/DNPH1/TYMS	6
BP	GO:0033127	regulation of histone phosphorylation	6/2619	13/18670	0.005362	0.03883	0.02912	MAPK3/ATM/CCNB1/AKAP8/CDK9/TWIST1	6
BP	GO:0035723	interleukin-15-mediated signaling pathway	6/2619	13/18670	0.005362	0.03883	0.02912	IL15RA/IL15/IL2RG/JAK1/IL2RB/STAT5A	6
BP	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway	6/2619	13/18670	0.005362	0.03883	0.02912	AR/IGFBP5/IGFBP4/PHIP/IGF1/GHSR	6
BP	GO:0045059	positive thymic T cell selection	6/2619	13/18670	0.005362	0.03883	0.02912	PTPRC/PTPN2/ZAP70/CD3E/CD3D/CD3G	6
BP	GO:0051451	myoblast migration	6/2619	13/18670	0.005362	0.03883	0.02912	SIX1/PLEKHO1/THBS4/ROCK1/NET1/SMO	6
BP	GO:0071350	cellular response to interleukin-15	6/2619	13/18670	0.005362	0.03883	0.02912	IL15RA/IL15/IL2RG/JAK1/IL2RB/STAT5A	6
BP	GO:0071352	cellular response to interleukin-2	6/2619	13/18670	0.005362	0.03883	0.02912	IL2RG/JAK1/PTPN2/IL2RB/STAT5A/PTK2B	6
BP	GO:1900272	negative regulation of long-term synaptic potentiation	6/2619	13/18670	0.005362	0.03883	0.02912	PTN/PRNP/CX3CR1/APOE/TYROBP/EPHA4	6
BP	GO:0051383	kinetochore organization	8/2619	21/18670	0.005492	0.03968	0.02976	NDC80/CENPE/MIS12/CENPT/SMC4/CENPC/CENPF/POGZ	8
BP	GO:0140131	positive regulation of lymphocyte chemotaxis	8/2619	21/18670	0.005492	0.03968	0.02976	CCL5/CXCL13/ADAM17/XCL1/TNFSF14/CCL7/PTK2B/CCR2	8
BP	GO:0031960	response to corticosteroid	35/2619	162/18670	0.005499	0.03968	0.02976	NOTCH1/IGFBP2/GOT1/CFLAR/DDIT4/SDC1/HSD11B2/BAD/EGFR/STC1/ABCA3/GPER1/ASS1/PAPPA/IL6/GHSR/AKR1C3/CPS1/PCK2/CASP9/USP8/CALCR/SSTR5/ZFP36L2/IL1RN/TYMS/AKAP13/HNMT/CDKN1A/KRAS/CSN1S1/SERPINF1/IL22/ATP2B1/TH	35
BP	GO:1904029	regulation of cyclin-dependent protein kinase activity	25/2619	106/18670	0.00554	0.03994	0.02995	TNFAIP3/CEBPA/DIRAS3/CCNA2/ADAM17/CDKN2C/EGFR/CCNL1/CKS1B/CDK4/MAPRE3/CKS2/CCNT2/CCNB2/CCNB1/CCNH/CDKN1C/PDGFB/PSMD10/CCNK/CCND2/KAT2B/CDKN1A/MNAT1/CCNL2	25
BP	GO:0009410	response to xenobiotic stimulus	57/2619	292/18670	0.005553	0.03998	0.02999	GSTA4/PTGS1/EPHX1/SLC18A2/BPHL/SNCA/CCNA2/RORA/EPHX2/AKR7A3/CFLAR/CHEK2/DDIT4/CES2/EGFR/NQO1/ADA/MGST3/GSTM4/PENK/PEA15/PPARG/GPX1/RANBP2/CXCR4/AKR7A2/CES3/RGS4/ASS1/CRHBP/GSTM5/GHSR/EGR1/CRYZ/CPS1/PDGFB/PCK2/SULT1A2/GSTM3/CASP9/USP8/FMO3/PPP3CA/SOD1/SRR/NAT2/PRKAA1/TAC1/CYB5R3/HNMT/STAT5A/S100A12/GHR/PTK2B/SERPINF1/HSPA5/TH	57
BP	GO:0071478	cellular response to radiation	40/2619	191/18670	0.005562	0.04	0.03	SFRP1/PTN/ECT2/GPR88/MFAP4/ERCC1/NIPBL/ATR/CHEK2/METAP1/CHEK1/ATM/USP47/GUCA1A/CRYAB/MYC/EGR1/NAMPT/AURKB/CASP9/RS1/DDB2/RAD1/RUVBL2/PTPRK/NET1/WRN/IFI16/ADIRF/RAD9A/METAP2/CDKN1A/N4BP1/EP300/TSPYL5/CRY1/ATF4/HSPA5/HMGA2/RBL2	40
BP	GO:0009072	aromatic amino acid family metabolic process	12/2619	39/18670	0.00562	0.0402	0.03015	FAH/HPD/HAAO/QDPR/PCBD1/IDO1/ASRGL1/GSTZ1/HDC/DCT/HNMT/TH	12
BP	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	12/2619	39/18670	0.00562	0.0402	0.03015	TNFAIP3/FAS/CFLAR/HGF/SERPINE1/ARHGEF2/PEA15/GPX1/NOS3/FAIM/RAF1/RNF34	12
BP	GO:2000816	negative regulation of mitotic sister chromatid separation	12/2619	39/18670	0.00562	0.0402	0.03015	ATM/PTTG1/TPR/BUB1B/LCMT1/NDC80/CCNB1/CDC20/AURKB/PTTG2/CENPF/FBXO5	12
BP	GO:0014015	positive regulation of gliogenesis	19/2619	74/18670	0.005621	0.0402	0.03015	PTN/NOTCH1/TREM2/TNFRSF1B/ZNF365/PRKCH/PRMT5/BIN1/PPARG/CXCR4/PRKCI/TSPO/IL6/P2RX4/HDAC1/OLIG2/ID2/CCR2/TENM4	19
BP	GO:0032507	maintenance of protein location in cell	19/2619	74/18670	0.005621	0.0402	0.03015	GPAA1/VPS13C/SKP1/CLMN/KDELR3/ARL2/SYNE2/BARD1/PINK1/ANK3/BBS4/TSPO/PML/ARL2BP/SCIN/TMSB10/TLN2/GOLPH3/HSPA5	19
BP	GO:0001906	cell killing	36/2619	168/18670	0.005644	0.04029	0.03022	HLA-C/DNASE1L3/RASGRP1/HLA-F/HLA-G/MICB/IL7R/HLA-A/RAB27A/PTPRC/APOL1/BAD/SLAMF7/HLA-B/HLA-E/PRF1/GZMB/CRTAM/ELANE/TUSC2/IFNG/GNLY/VAMP7/TYROBP/XCL1/DEFA6/HMGN2/ULBP2/CCL13/MBL2/EMP2/CTSG/DEFA5/CEBPG/S100A12/CD59	36
BP	GO:0010819	regulation of T cell chemotaxis	7/2619	17/18670	0.005673	0.04029	0.03022	CXCL10/CCL5/CXCL13/ADAM17/XCL1/TNFSF14/CCR2	7
BP	GO:0032740	positive regulation of interleukin-17 production	7/2619	17/18670	0.005673	0.04029	0.03022	SPHK1/IL15/LY9/IL6/PRKCQ/NOD2/MYD88	7
BP	GO:0060644	mammary gland epithelial cell differentiation	7/2619	17/18670	0.005673	0.04029	0.03022	FOXF1/HIF1A/HOXA5/ID2/ERBB4/CEBPB/SMO	7
BP	GO:0061323	cell proliferation involved in heart morphogenesis	7/2619	17/18670	0.005673	0.04029	0.03022	SIX1/NOTCH1/SOX9/PIM1/BMP4/TBX5/RBPJ	7
BP	GO:2000136	regulation of cell proliferation involved in heart morphogenesis	7/2619	17/18670	0.005673	0.04029	0.03022	SIX1/NOTCH1/SOX9/PIM1/BMP4/TBX5/RBPJ	7
BP	GO:0030260	entry into host cell	30/2619	134/18670	0.005723	0.04042	0.03032	TFRC/SLAMF1/NUP153/EGFR/SIVA1/ITGA5/UVRAG/TNFRSF14/TRIM26/IDE/CCR5/EXOC7/ITGB7/CXCR4/CD81/CR1/TRIM21/EXOC2/AXL/IFITM2/ITGB5/CDK1/FCN1/TYRO3/SLC20A2/CXADR/KPNA3/CXCL8/ANPEP/NPC1	30
BP	GO:0044409	entry into host	30/2619	134/18670	0.005723	0.04042	0.03032	TFRC/SLAMF1/NUP153/EGFR/SIVA1/ITGA5/UVRAG/TNFRSF14/TRIM26/IDE/CCR5/EXOC7/ITGB7/CXCR4/CD81/CR1/TRIM21/EXOC2/AXL/IFITM2/ITGB5/CDK1/FCN1/TYRO3/SLC20A2/CXADR/KPNA3/CXCL8/ANPEP/NPC1	30
BP	GO:0051806	entry into cell of other organism involved in symbiotic interaction	30/2619	134/18670	0.005723	0.04042	0.03032	TFRC/SLAMF1/NUP153/EGFR/SIVA1/ITGA5/UVRAG/TNFRSF14/TRIM26/IDE/CCR5/EXOC7/ITGB7/CXCR4/CD81/CR1/TRIM21/EXOC2/AXL/IFITM2/ITGB5/CDK1/FCN1/TYRO3/SLC20A2/CXADR/KPNA3/CXCL8/ANPEP/NPC1	30
BP	GO:0051828	entry into other organism involved in symbiotic interaction	30/2619	134/18670	0.005723	0.04042	0.03032	TFRC/SLAMF1/NUP153/EGFR/SIVA1/ITGA5/UVRAG/TNFRSF14/TRIM26/IDE/CCR5/EXOC7/ITGB7/CXCR4/CD81/CR1/TRIM21/EXOC2/AXL/IFITM2/ITGB5/CDK1/FCN1/TYRO3/SLC20A2/CXADR/KPNA3/CXCL8/ANPEP/NPC1	30
BP	GO:0046849	bone remodeling	22/2619	90/18670	0.005723	0.04042	0.03032	TNFAIP3/SFRP1/PTN/TNFRSF11B/TFRC/CD38/PTH1R/EGFR/LTBP3/TNFRSF11A/GDF5/TCIRG1/S1PR1/ADRB2/LRP5/RAC2/IL6/SUCO/CA2/SNX10/NCDN/PTK2B	22
BP	GO:0050678	regulation of epithelial cell proliferation	71/2619	378/18670	0.005738	0.04048	0.03036	TNFAIP3/SIX1/SFRP1/DYSF/NUPR1/PTN/NOTCH1/AR/STAT1/SOX9/CCL5/PRKD2/FBXW7/PGF/THBS4/SMAD3/CFLAR/ADAM17/BAD/EGFR/IFT52/APOE/RUNX3/BCL11B/HTRA1/BMP4/GDF5/CYP7B1/ERBB2/HTR2B/TNMD/MED1/PPARG/GPX1/PPP1R16B/OSR2/KRIT1/PEX2/IGF1/KDR/MYC/ANG/CDKN1C/GHSR/BRCA2/EREG/PDGFB/DEAF1/MMP12/VEGFA/HMGB1/NOD2/MAGED1/SCG2/PTPRK/HIF1A/HOXA5/WDR13/HAS2/NGFR/STAT5A/TCF7L2/ATF2/XBP1/FZD7/SMO/SERPINF1/REG3A/TWIST1/VEGFB/NRAS	71
BP	GO:0051928	positive regulation of calcium ion transport	28/2619	123/18670	0.005849	0.04117	0.03088	CXCL9/CXCL10/ATP1B1/CCL5/PLCG2/SNCA/SRI/CXCL11/FGF14/LILRA2/STC1/EHD3/GPER1/F2R/TSPO/S100A1/HCRT/PDGFB/XCL1/CD19/P2RX4/CALCR/CACNB2/CACNA1D/TRPV2/LGALS3/HSPA2/ATP2B1	28
BP	GO:0071621	granulocyte chemotaxis	28/2619	123/18670	0.005849	0.04117	0.03088	CXCL9/DYSF/CXCL10/CCL5/MAPK3/CXCL13/THBS4/CCL18/CXCL11/CXCL2/CCL8/RAC2/XCL1/CCR7/CXCL3/CXCR2/SCG2/CCL13/IL17RC/IL1RN/PIK3CD/MPP1/S100A12/LGALS3/CXADR/CCL7/CXCL8/IL17RA	28
BP	GO:0060271	cilium assembly	69/2619	366/18670	0.005859	0.0412	0.0309	NOTCH1/CETN2/TCTN1/GALNT11/CEP135/IFT46/TMEM231/CNTRL/ARL3/ATP6V0D1/NDE1/HAUS3/RPGR/CBY1/SYNE2/TCTN3/NME5/ABCC4/ASAP1/IFT52/ATXN10/ACTR3/DCTN3/TMEM80/DYNLRB1/HAUS2/C2CD3/EHD3/MNS1/SFI1/BBS1/BBS4/TTLL1/RABEP2/B9D1/CDC14A/LAMA5/FGFR1OP/DCTN2/TUBA4A/C5orf30/PCM1/SPATA6/CLASP1/TNPO1/SPAG1/CLUAP1/DYNC1H1/IFT140/ARHGAP35/IQCB1/CSNK1E/WDR11/SNX10/ALMS1/AKAP9/CYLD/UNC119B/CDK1/VDAC3/CDKL5/IFT22/CEP290/CEP63/FLNA/OFD1/TCTN2/ACTR2/DYNC2LI1	69
BP	GO:0010463	mesenchymal cell proliferation	13/2619	44/18670	0.005898	0.04138	0.03104	SIX1/PTN/STAT1/SOX9/CTNNBIP1/BMP4/WNT11/FOXF1/LRP5/SIX2/MYC/VEGFA/SMO	13
BP	GO:0033046	negative regulation of sister chromatid segregation	13/2619	44/18670	0.005898	0.04138	0.03104	ATM/PTTG1/TPR/BUB1B/LCMT1/NDC80/CCNB1/CDC20/ATRX/AURKB/PTTG2/CENPF/FBXO5	13
BP	GO:1990748	cellular detoxification	26/2619	112/18670	0.005908	0.0414	0.03105	GCH1/LTC4S/PTGS1/AKR1B10/FBLN5/ALOX5AP/APOM/NQO1/APOE/GPX3/PRDX6/MGST3/GSTZ1/PXDN/GPX1/ESD/CAT/GPX4/NOS3/IPCEF1/GSTM3/SOD1/HBB/PRDX2/SESN1/TXNRD2	26
BP	GO:0046579	positive regulation of Ras protein signal transduction	17/2619	64/18670	0.005948	0.0416	0.0312	NOTCH1/JAK2/RASGRP1/STK19/SHOC2/ARRB1/F2R/NTRK1/AUTS2/IGF1/MAP4K4/AKAP13/MAPRE2/COL3A1/KRAS/GPR4/EPOR	17
BP	GO:0006362	transcription elongation from RNA polymerase I promoter	10/2619	30/18670	0.005976	0.0416	0.0312	POLR2L/POLR2E/POLR2F/TAF1D/POLR1B/CCNH/ERCC2/MNAT1/POLR1C/GTF2H3	10
BP	GO:0032607	interferon-alpha production	10/2619	30/18670	0.005976	0.0416	0.0312	STAT1/RIPK2/TBK1/NMI/IRF3/CHUK/MMP12/HMGB1/SETD2/TLR8	10
BP	GO:0032743	positive regulation of interleukin-2 production	10/2619	30/18670	0.005976	0.0416	0.0312	PRKD2/RIPK2/MALT1/PTPRC/CD83/CD28/CD3E/GLMN/PRKCQ/CCR2	10
BP	GO:0050869	negative regulation of B cell activation	10/2619	30/18670	0.005976	0.0416	0.0312	TNFAIP3/SFRP1/PARP3/ATM/TNFRSF21/CTLA4/THOC1/HMGB3/TYROBP/ID2	10
BP	GO:1904837	beta-catenin-TCF complex assembly	10/2619	30/18670	0.005976	0.0416	0.0312	TCF7/LEF1/TRRAP/MYC/KAT5/TLE3/HDAC1/TCF7L2/TLE2/EP300	10
BP	GO:0014031	mesenchymal cell development	21/2619	85/18670	0.006011	0.04174	0.0313	NOTCH1/FOLR1/SOX9/SEMA4D/MAPK3/SEMA4A/FOXC1/SEMA3A/BMP4/SEMA4C/HTR2B/FAM172A/LAMA5/SEMA3F/EFNB1/SEMA3E/PHACTR4/HIF1A/ERBB4/SMO/TWIST1	21
BP	GO:0030100	regulation of endocytosis	55/2619	281/18670	0.006014	0.04174	0.0313	IL15RA/DYSF/SPHK1/TREM2/PLCG2/ANGPT1/SNCA/CLU/USP46/IL15/SH3GL1/IL2RG/SYT11/RAB27A/LRPAP1/PTPRC/ZFYVE16/EGF/MERTK/MCTP1/SERPINE1/APOE/NTF3/HFE/LMAN2/BIN1/TSPAN1/MAGI2/SELE/HNRNPK/PPARG/ROCK1/FGR/SNX17/ARRB1/IFNG/APOC1/CD63/PIK3CB/NR1H2/IL2RB/CD151/AXL/SLC11A1/VEGFA/HMGB1/C4BPB/PPP3CA/SOD1/MBL2/RUFY2/RAB20/HIP1R/LGALS3/NEDD4L	55
BP	GO:0008016	regulation of heart contraction	50/2619	251/18670	0.006031	0.04174	0.0313	ADORA3/GCH1/SCN1B/ATP1B1/SNTA1/JAK2/FXYD1/ATP2A3/SRI/KCNQ1/CELF2/KCNK15/SEMA3A/FXYD6/FGF13/STC1/ADA/BIN1/EHD3/KCNK3/ASPH/KCNJ2/MYL3/ITPR2/NPR2/RGS4/ATP2B2/AGT/NOS3/S100A1/HBEGF/P2RX4/MYL4/IRX5/CACNB2/KCNN2/GAA/AKAP9/RANGRF/TAC1/ATP2B4/CACNA1D/KCND1/CXADR/CACNA2D3/FLNA/SLC1A1/ATP2B1/TH/CORIN	50
BP	GO:0048863	stem cell differentiation	51/2619	257/18670	0.006038	0.04174	0.0313	MTF2/SFRP1/PTN/NOTCH1/FOLR1/JARID2/SOX9/SEMA4D/MAPK3/SEMA4A/PTPRC/FOXC1/ZNF281/MEOX1/PSMB9/SEMA3A/LTBP3/N4BP2L2/KIT/BMP4/SEMA4C/HTR2B/FAM172A/PUS7/PSMC2/KDM3A/GPM6A/LAMA5/PSMB6/SEMA3F/TBX5/EFNB1/PSMC3/RBPJ/PSMD8/PSMB5/BATF/SEMA3E/ZFP36L2/PHACTR4/PSMD10/HIF1A/ERCC2/SETD2/SIX3/TCF3/ERBB4/HOXA7/SMO/HMGA2/TWIST1	51
BP	GO:0001913	T cell mediated cytotoxicity	14/2619	49/18670	0.006045	0.04174	0.0313	HLA-C/HLA-F/HLA-G/MICB/IL7R/HLA-A/RAB27A/PTPRC/HLA-B/HLA-E/PRF1/XCL1/ULBP2/EMP2	14
BP	GO:0071349	cellular response to interleukin-12	14/2619	49/18670	0.006045	0.04174	0.0313	LCP1/JAK2/HNRNPA2B1/TYK2/RALA/CAPZA1/JAK1/LMNB1/STAT4/IFNG/SOD1/PAK2/RAP1B/RPLP0	14
BP	GO:1990090	cellular response to nerve growth factor stimulus	14/2619	49/18670	0.006045	0.04174	0.0313	MICALL1/STMN2/NTRK2/NTF3/MAGI2/NTRK1/ACAP2/SORT1/USP8/TAC1/CIB1/CREB1/HSPA5/BDNF	14
BP	GO:0061077	chaperone-mediated protein folding	16/2619	59/18670	0.006049	0.04174	0.0313	GAK/CLU/PEX19/HSPH1/CHORDC1/DNAJB14/HSPB6/CRTAP/HSPB1/HSPA6/TRAP1/BAG1/PPIB/HSPA2/DNAJC24/HSPA5	16
BP	GO:0032655	regulation of interleukin-12 production	15/2619	54/18670	0.006087	0.04191	0.03143	IRAK3/IRF1/RIPK2/SLAMF1/HLA-G/IDO1/CD40/NFKB1/IFNG/MAPK11/TNFSF4/HMGB1/CCR7/TLR8/CD40LG	15
BP	GO:0043392	negative regulation of DNA binding	15/2619	54/18670	0.006087	0.04191	0.03143	NFKBIA/JAK2/FBXW7/SRI/CTNNBIP1/MDFI/LEF1/GZMA/ID4/IFI16/ID2/ID3/SMO/HMGA2/DDIT3	15
BP	GO:0030307	positive regulation of cell growth	36/2619	169/18670	0.006226	0.04282	0.03212	SFRP1/SPHK1/SEMA4D/MACF1/CD38/ADAM17/EGFR/ITSN2/ERBB2/EFNA5/LEF1/USP47/CXCR4/SYT17/FGFR1OP/IGF1/RND2/HBEGF/TAF9B/VEGFA/PIN1/PSMD10/DNPH1/CIB1/GOLGA4/TRPV2/CDKL5/SYT1/CYFIP1/TRIM32/RPS6KA1/PTK2B/DSCAM/CPNE6/BDNF/NEDD4L	36
BP	GO:1990266	neutrophil migration	27/2619	118/18670	0.00625	0.04292	0.03219	SLAMF8/CXCL9/DYSF/CXCL10/CCL5/CXCL13/THBS4/CCL18/CXCL11/PECAM1/CXCL2/CCL8/RAC2/IRAK4/XCL1/CCR7/CXCL3/CXCR2/CCL13/IL1RN/PIK3CD/MPP1/S100A12/LGALS3/CXADR/CCL7/CXCL8	27
BP	GO:0035637	multicellular organismal signaling	42/2619	204/18670	0.006254	0.04292	0.03219	SCN1B/ATP1B1/FXYD1/GPR88/ATP2A3/SRI/KCNQ1/KCNK15/FXYD6/NTRK2/BIN1/EHD3/KCNK3/TYMP/ASPH/KCNJ2/ANK3/GPER1/S1PR1/ITPR2/NPR2/ATP2B2/AGT/HCRT/GHSR/P2RX4/CACNB2/SOD1/KCNN2/AKAP9/RANGRF/SCN9A/ATP2B4/CACNA1D/KCND1/CXADR/CACNA2D3/FLNA/KCNMB2/ATP2B1/CORIN/SCN3A	42
BP	GO:0001909	leukocyte mediated cytotoxicity	25/2619	107/18670	0.006288	0.04304	0.03228	HLA-C/DNASE1L3/RASGRP1/HLA-F/HLA-G/MICB/IL7R/HLA-A/RAB27A/PTPRC/SLAMF7/HLA-B/HLA-E/PRF1/GZMB/CRTAM/ELANE/TUSC2/VAMP7/TYROBP/XCL1/ULBP2/EMP2/CTSG/CEBPG	25
BP	GO:0033045	regulation of sister chromatid segregation	20/2619	80/18670	0.006292	0.04304	0.03228	NIPBL/ATM/DLGAP5/PTTG1/TPR/DDX11/BUB1B/LCMT1/SMC5/NDC80/CENPE/CCNB1/CDC20/ATRX/AURKB/SFPQ/TACC3/PTTG2/CENPF/FBXO5	20
BP	GO:0048194	Golgi vesicle budding	20/2619	80/18670	0.006292	0.04304	0.03228	FOLR1/SEC24A/SERPINA1/PPP6R3/SEC22B/SEC13/F8/TRAPPC2L/CNIH1/TRAPPC10/PRKCI/SEC16A/TMED2/TMED9/TMED10/ANKRD28/GOLPH3/VAPA/NAPA/CD59	20
BP	GO:0000075	cell cycle checkpoint	44/2619	216/18670	0.006372	0.04354	0.03265	TOPBP1/NBN/RFWD3/ATR/CRADD/CHEK2/CHEK1/ATM/DNA2/THOC1/CHFR/TPR/BUB1B/PEA15/LCMT1/DONSON/SETMAR/KNTC1/NDC80/PLK2/CCNB1/TAOK1/PML/CDC20/AURKB/DTL/TOP2A/RAD1/NABP2/TIMELESS/TAOK3/BABAM1/GTSE1/CDK1/RAD9A/CDKN1A/WEE1/ATF2/EP300/CEP63/CRY1/HMGA2/CENPF/RBL2	44
BP	GO:0007098	centrosome cycle	28/2619	124/18670	0.006568	0.04483	0.03362	CETN2/CEP135/NDE1/HAUS3/ARL2/MDM1/CHEK1/SYNE2/UVRAG/CHORDC1/HAUS2/C2CD3/BBS4/PPP1R12A/PLK2/KIF11/PCM1/CHMP2A/BRCA2/CHD3/KIAA0753/ALMS1/CHMP1B/CDK1/KAT2B/CEP63/SPICE1/NUP62	28
BP	GO:0032735	positive regulation of interleukin-12 production	11/2619	35/18670	0.006613	0.04499	0.03374	IRF1/RIPK2/HLA-G/IDO1/CD40/IFNG/MAPK11/TNFSF4/HMGB1/CCR7/CD40LG	11
BP	GO:0042092	type 2 immune response	11/2619	35/18670	0.006613	0.04499	0.03374	IL27RA/IL4R/IDO1/DENND1B/CD81/IL6/XCL1/TNFSF4/NOD2/BATF/CCR2	11
BP	GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway	11/2619	35/18670	0.006613	0.04499	0.03374	TNFAIP3/NFKBIA/BIRC3/RIPK2/BIRC2/PTPN22/UBB/NOD2/CYLD/NOD1/IKBKG	11
BP	GO:0009411	response to UV	31/2619	141/18670	0.006634	0.04509	0.03382	PTN/SCARA3/MFAP4/ERCC1/CIRBP/ATR/SDF4/CHEK1/EGFR/USP47/GPX1/CAT/ELANE/MYC/BRCA2/PML/AURKB/CASP9/DTL/DDB2/RUVBL2/PTPRK/WRN/ERCC2/PRKAA1/CDKN1A/N4BP1/EP300/TRIM32/ATF4/RBL2	31
BP	GO:0001556	oocyte maturation	9/2619	26/18670	0.006803	0.04607	0.03456	CDC25B/NPR2/CCNB1/ANG/BRCA2/EREG/PTK2B/DAZL/FBXO5	9
BP	GO:0032800	receptor biosynthetic process	9/2619	26/18670	0.006803	0.04607	0.03456	JAK2/SEC24A/CNPY2/HNRNPK/PPARG/IFNG/HIF1A/HOXA5/HDAC1	9
BP	GO:0042326	negative regulation of phosphorylation	85/2619	468/18670	0.006805	0.04607	0.03456	TNFAIP3/GBP1/DUSP5/SFRP1/NUPR1/CEBPA/MICAL1/IRAK3/BTN2A2/ENPP1/SEMA4D/ADAR/PRKAR2A/ANGPT1/SNCA/DUSP6/TNIP1/UCHL1/PTPRC/HGF/CBFA2T3/DDIT4/PID1/CDKN2C/DEPTOR/PRNP/NCK2/PINK1/APOE/CHORDC1/ATF3/NTF3/SOCS1/CTDSPL/LAX1/BMP4/DNAJA1/PTPN22/PHB/FKBP8/GPER1/PTPN2/CHMP6/FGFR1OP/ARRB1/HSPB1/CBLB/FOXM1/NDRG2/IFNG/PRR5L/LMO3/RGS4/TRIB1/SIRT3/PPM1E/LRP5/INSM1/CCNB1/MYC/RASIP1/CDKN1C/TAF7/DUSP2/EIF3A/PIN1/ANKLE2/NCOR1/DNAJC3/PSMD10/CYLD/NF2/TARDBP/TAOK3/CIB1/RHOH/PAK2/GGNBP2/KAT2B/CDKN1A/FBLN1/SH2B3/MVP/TWIST1/NUP62	85
BP	GO:0002709	regulation of T cell mediated immunity	18/2619	70/18670	0.006809	0.04607	0.03456	HLA-C/TNFRSF1B/MALT1/HLA-F/HLA-G/IL7R/HLA-A/PTPRC/HLA-B/HLA-E/HFE/CD81/IL6/XCL1/TNFSF4/HMGB1/CCR2/FBXO38	18
BP	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	21/2619	86/18670	0.006925	0.04671	0.03504	COPZ2/BNIP1/KDELR3/KIF2A/UVRAG/RACGAP1/TMED3/LMAN2/SEC22B/TAPBP/ERGIC3/CENPE/KIF11/KIF4A/USE1/KIF15/TMED2/TMED9/TMED10/GOLPH3/NAPA	21
BP	GO:0070542	response to fatty acid	21/2619	86/18670	0.006925	0.04671	0.03504	SFRP1/PID1/BAD/CDK4/HMGCL/PPARG/PTGER4/PTGFR/CAT/ASS1/CCNB1/AKR1C3/CPS1/TNFSF4/CCR7/LPL/AKAP8/PRKAA1/CREB1/ID3/FABP3	21
BP	GO:0008406	gonad development	44/2619	217/18670	0.006933	0.04671	0.03504	HOXA11/SFRP1/NUPR1/AR/HOXA10/KDM5A/SOX9/ERCC1/ASPM/FOXC1/SDC1/SEMA3A/ARID4B/ATM/INSR/KIT/ING2/PLEKHA1/ARRB1/NTRK1/ZFPM2/NOS3/RAB13/NASP/ANG/BRCA2/AKR1C3/EREG/ATRX/VEGFA/UBB/IRX5/ARID4A/SOD1/TMF1/MEA1/BCL2L2/GDF9/PATZ1/SGPL1/INHBB/FLNA/CEBPB/HSPA5	44
BP	GO:0043393	regulation of protein binding	44/2619	217/18670	0.006933	0.04671	0.03504	MAPK3/RIPK2/ANGPT1/SLPI/PCBD1/LRPAP1/PTPRF/SMARCD3/TDG/CTNNBIP1/APOE/GSK3B/HFE/BMP4/DDX11/MAPRE3/SPON1/LEF1/RFNG/PIM2/ROCK1/NMD3/ARRB1/ADRB2/PLK2/LDOC1/PDGFB/EPHA4/AURKB/PLXND1/PIN1/CSNK1E/RUVBL2/PEX14/CAMK1/CYLD/TCF7L2/HIP1R/LGALS3/EP300/CAPRIN2/MARK3/HSPA5/BDNF	44
BP	GO:0045444	fat cell differentiation	45/2619	223/18670	0.006973	0.04693	0.0352	WIF1/SFRP1/DYSF/CEBPA/WNT5B/ENPP1/SH2B2/NIPBL/SMAD3/RORA/CBY1/FTO/SDF4/SOCS1/OSBPL8/AAMDC/MED1/PPARG/GPX1/BBS4/GPER1/PEX11A/ADRB2/ID4/LMO3/ZFPM2/LRP5/ASXL2/IL6/SORT1/ZFP36L2/LPL/CREB1/ADIRF/ID2/TCF7L2/ATF2/EP300/TRIM32/XBP1/ALDH6A1/INHBB/CEBPB/HMGA2/DDIT3	45
BP	GO:0090184	positive regulation of kidney development	12/2619	40/18670	0.007023	0.04708	0.03531	SIX1/SOX9/CFLAR/BMP4/AGT/MYC/EGR1/PDGFB/VEGFA/MAGED1/IL6R/SMO	12
BP	GO:0098534	centriole assembly	12/2619	40/18670	0.007023	0.04708	0.03531	CETN2/CEP135/MDM1/C2CD3/PLK2/CHMP2A/KIAA0753/ALMS1/KAT2B/CEP63/SPICE1/NUP62	12
BP	GO:1905819	negative regulation of chromosome separation	12/2619	40/18670	0.007023	0.04708	0.03531	ATM/PTTG1/TPR/BUB1B/LCMT1/NDC80/CCNB1/CDC20/AURKB/PTTG2/CENPF/FBXO5	12
BP	GO:0014823	response to activity	17/2619	65/18670	0.007025	0.04708	0.03531	PTN/FIS1/ANGPT2/CXCR4/CAT/HADH/POSTN/OXCT1/AGT/HIF1A/PRKAA1/CREB1/CDK1/CRY1/COL4A2/UQCRC1/TH	17
BP	GO:0090316	positive regulation of intracellular protein transport	33/2619	153/18670	0.007054	0.04723	0.03542	ZIC1/ECT2/FIS1/FBXW7/SMAD3/MICALL2/PRNP/PINK1/GSK3B/TPR/ERBB2/TMEM30A/ANK3/CD81/IFNG/PRR5L/PCM1/RAC2/SEC16A/ATG13/EDEM1/VAMP2/CAMK1/PRKAA1/TARDBP/CIB1/GTSE1/TCF7L2/CEP290/UBL5/FLNA/UBR5/SMO	33
BP	GO:0007292	female gamete generation	30/2619	136/18670	0.007129	0.04768	0.03576	CDC25B/PTN/ERCC1/ASPM/IL4R/SOS1/ATM/HPGD/NCAPH/DIAPH2/NPR2/IGF1/NOS3/CCNB1/ETV6/ANG/BRCA2/EREG/UBB/RAD51C/LGR5/YTHDC2/TOP2A/USP9X/GDF9/PIWIL2/INHBB/PTK2B/DAZL/FBXO5	30
BP	GO:0002294	CD4-positive, alpha-beta T cell differentiation involved in immune response	16/2619	60/18670	0.007197	0.04808	0.03606	RIPK2/MALT1/RORA/SEMA4A/IL4R/GPR183/LEF1/PTGER4/RC3H2/RELB/IFNG/LY9/IL6/TNFSF4/HMGB1/BATF	16
BP	GO:0098727	maintenance of cell number	34/2619	159/18670	0.007235	0.04828	0.03621	MTF2/SFRP1/PTN/NOTCH1/CDH2/SOX9/NIPBL/ASPM/POLR2J/POLR2I/POLR2L/NCOA3/EZH2/POLR2E/POLR2F/KIT/POLR2C/KDM3A/ARID1A/PCM1/IGF1/SIX2/POLR2G/RBPJ/MED7/ZFP36L2/SMC1A/DPPA4/RAF1/MED27/PIWIL2/FZD7/SMO/HMGA2	34
BP	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	13/2619	45/18670	0.00725	0.04828	0.03621	NUPR1/CHEK2/DDIT4/ING2/DYRK2/HNRNPK/CD44/BRCA2/TAF9B/PML/IFI16/CDKN1A/EP300	13
BP	GO:0051985	negative regulation of chromosome segregation	13/2619	45/18670	0.00725	0.04828	0.03621	ATM/PTTG1/TPR/BUB1B/LCMT1/NDC80/CCNB1/CDC20/ATRX/AURKB/PTTG2/CENPF/FBXO5	13
BP	GO:0014032	neural crest cell development	20/2619	81/18670	0.007278	0.04832	0.03624	FOLR1/SOX9/SEMA4D/MAPK3/SEMA4A/FOXC1/SEMA3A/BMP4/SEMA4C/HTR2B/FAM172A/LAMA5/SEMA3F/EFNB1/SEMA3E/PHACTR4/HIF1A/ERBB4/SMO/TWIST1	20
BP	GO:0014855	striated muscle cell proliferation	20/2619	81/18670	0.007278	0.04832	0.03624	SIX1/NOTCH1/JARID2/JAK2/ANGPT1/CFLAR/FOXC1/RBP4/PIM1/RXRA/FGF20/ZFPM2/MAPK11/TBX5/CCNB1/RBPJ/PAXBP1/CDK1/ERBB4/TENM4	20
BP	GO:0110110	positive regulation of animal organ morphogenesis	20/2619	81/18670	0.007278	0.04832	0.03624	TNFAIP3/SIX1/HOXA11/PTN/NOTCH1/AR/SOX9/CFLAR/PIM1/BMP4/MED1/AGT/MYC/RBPJ/VEGFA/MAGED1/HOXC11/XBP1/SMO/TWIST1	20
BP	GO:0045620	negative regulation of lymphocyte differentiation	15/2619	55/18670	0.007307	0.04844	0.03633	SFRP1/IRF1/IL4R/CTLA4/RUNX3/SOCS1/BMP4/ERBB2/PTPN2/RC3H2/HMGB3/TNFSF4/HMGB1/PRDX2/ID2	15
BP	GO:0001961	positive regulation of cytokine-mediated signaling pathway	14/2619	50/18670	0.007334	0.04844	0.03633	TREM2/RIPK2/AGPAT1/TBK1/ADAM17/CASP4/MED1/IRF3/CXCR4/TXK/AXL/MMP12/HIF1A/TRIM32	14
BP	GO:0006570	tyrosine metabolic process	5/2619	10/18670	0.007373	0.04844	0.03633	FAH/HPD/GSTZ1/DCT/TH	5
BP	GO:0007220	Notch receptor processing	5/2619	10/18670	0.007373	0.04844	0.03633	GALNT11/ADAM17/PSENEN/APH1B/APH1A	5
BP	GO:0030647	aminoglycoside antibiotic metabolic process	5/2619	10/18670	0.007373	0.04844	0.03633	AKR1B1/AKR1B10/AKR7A2/AKR1C3/AKR1C4	5
BP	GO:0036500	ATF6-mediated unfolded protein response	5/2619	10/18670	0.007373	0.04844	0.03633	MBTPS1/ATF6/XBP1/HSPA5/DDIT3	5
BP	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity	5/2619	10/18670	0.007373	0.04844	0.03633	FBXW7/ADAM17/EGF/EREG/NCF1	5
BP	GO:0070099	regulation of chemokine-mediated signaling pathway	5/2619	10/18670	0.007373	0.04844	0.03633	TREM2/CCL5/HIF1A/PADI2/SH2B3	5
BP	GO:0072124	regulation of glomerular mesangial cell proliferation	5/2619	10/18670	0.007373	0.04844	0.03633	CFLAR/BMP4/EGR1/PDGFB/IL6R	5
BP	GO:0007034	vacuolar transport	31/2619	142/18670	0.007375	0.04844	0.03633	DENND3/GAK/VPS13C/CLU/ATP6V0D1/VPS37C/ZFYVE16/PINK1/GNPTAB/BIN1/NDFIP1/EHD3/TRAK1/VTI1B/CHMP6/ADRB2/VPS16/CHMP2A/VAMP7/GPRASP1/USE1/TMEM50B/SORT1/CHMP1B/HOOK2/NPC1/PSAP/CLEC16A/AP4M1/ARSB/HMGXB4	31
BP	GO:0042063	gliogenesis	56/2619	290/18670	0.007451	0.04889	0.03667	PTN/NOTCH1/TREM2/CDH2/TNFRSF1B/SOX9/LAMC3/MAPK3/CLU/GPR183/EZH2/SYNE2/CDKN2C/EGFR/TNFRSF21/NDN/CX3CR1/ZNF365/PRKCH/NTRK2/PRMT5/BIN1/PENK/ERBB2/LEF1/NAB1/PPARG/CXCR4/ADAM22/ID4/CERS2/IFNG/MXRA8/PRKCI/TSPO/IL6/MYOC/EPHA4/P2RX4/NFE2L1/SOD1/ERCC2/HDAC1/NF2/FA2H/CREB1/CDK1/OLIG2/ID2/KRAS/PLP1/PTK2B/FGF5/CCR2/SMO/TENM4	56
BP	GO:0016241	regulation of macroautophagy	36/2619	171/18670	0.007543	0.04926	0.03694	NUPR1/MAPK3/RIPK2/VPS13C/TBK1/ATP6V0D1/UCHL1/PIKFYVE/UVRAG/PINK1/CAPNS1/RRAGA/PRKAG1/SEC22B/EXOC7/PRKAB1/PIM2/POLDIP2/ADRB2/KDR/UBQLN4/ATP6V0E2/ATG13/LAMTOR2/MLST8/OPTN/HIF1A/PRKAA1/NOD1/IKBKG/RRAGD/SESN1/NPC1/EXOC1/CLEC16A/PIK3CA	36
BP	GO:0035601	protein deacylation	24/2619	103/18670	0.007584	0.04926	0.03694	BEX4/KDM5A/PRKD2/NIPBL/TADA3/PINK1/MSL3/ING2/ZNHIT1/PHB/NEK3/IFNG/SIRT3/VEGFA/SFPQ/RCOR1/AKAP8/HDAC1/PRKAA1/SAP30/EP300/BAZ2A/MORF4L1/SIRT7	24
BP	GO:0006085	acetyl-CoA biosynthetic process	8/2619	22/18670	0.007585	0.04926	0.03694	PDK2/MPC2/GSTZ1/ACAT1/DLD/PDK1/PDHB/MPC1	8
BP	GO:0048305	immunoglobulin secretion	8/2619	22/18670	0.007585	0.04926	0.03694	RBP4/HLA-E/LAX1/CD40/IL6/TNFSF4/XBP1/CD40LG	8
BP	GO:0051000	positive regulation of nitric-oxide synthase activity	8/2619	22/18670	0.007585	0.04926	0.03694	GCH1/APOE/HTR2B/S100A1/HIF1A/NOD1/KRAS/PTK2B	8
BP	GO:0071379	cellular response to prostaglandin stimulus	8/2619	22/18670	0.007585	0.04926	0.03694	SFRP1/PPARG/PTGER4/PTGFR/AKR1C3/TNFSF4/AKAP8/PRKAA1	8
BP	GO:0090189	regulation of branching involved in ureteric bud morphogenesis	8/2619	22/18670	0.007585	0.04926	0.03694	SIX1/SOX9/BMP4/AGT/SIX2/VEGFA/MAGED1/SMO	8
BP	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus	8/2619	22/18670	0.007585	0.04926	0.03694	NOTCH1/CREB3/RBPJ/VEGFA/HIF1A/EP300/XBP1/ATF4	8
BP	GO:1901685	glutathione derivative metabolic process	8/2619	22/18670	0.007585	0.04926	0.03694	HPGDS/GSTA4/MGST3/GSTM4/GSTZ1/ESD/GSTM5/GSTM3	8
BP	GO:1901687	glutathione derivative biosynthetic process	8/2619	22/18670	0.007585	0.04926	0.03694	HPGDS/GSTA4/MGST3/GSTM4/GSTZ1/ESD/GSTM5/GSTM3	8
BP	GO:1904018	positive regulation of vasculature development	46/2619	230/18670	0.007594	0.04927	0.03695	NOTCH1/SPHK1/PRKD2/PGF/DDAH1/PRKCB/TMEM100/CFLAR/HGF/ITGAX/ITGA5/CX3CR1/SERPINE1/ANGPT2/KIT/HSPB6/JAK1/CMA1/PPP1R16B/CD40/GPER1/CXCR4/TIE1/HSPB1/CDH5/PLK2/NOS3/FGF18/S100A1/KDR/GHSR/EGR1/PDGFB/MTDH/VEGFA/CXCR2/MAP3K3/HIF1A/CIB1/IL6R/XBP1/CXCL8/PTK2B/HMGA2/TWIST1/VEGFB	46
BP	GO:0030500	regulation of bone mineralization	19/2619	76/18670	0.007623	0.04941	0.03706	PTN/NELL1/SOX9/ENPP1/MGP/ANKH/SMAD3/ATRAID/LTBP3/BMP4/S1PR1/OSR2/ADRB2/COMP/HIF1A/PTK2B/ATP2B1/TWIST1/SRGN	19
BP	GO:0006363	termination of RNA polymerase I transcription	10/2619	31/18670	0.007732	0.04975	0.03732	POLR2L/POLR2E/POLR2F/TAF1D/POLR1B/CCNH/ERCC2/MNAT1/POLR1C/GTF2H3	10
BP	GO:0007202	activation of phospholipase C activity	10/2619	31/18670	0.007732	0.04975	0.03732	ITK/EGFR/NTRK2/HTR2B/SELE/AGT/ANG/TXK/LPAR2/BDNF	10
BP	GO:0031572	G2 DNA damage checkpoint	10/2619	31/18670	0.007732	0.04975	0.03732	NBN/CHEK1/ATM/DONSON/TAOK1/DTL/TAOK3/BABAM1/CDK1/HMGA2	10
BP	GO:0035767	endothelial cell chemotaxis	10/2619	31/18670	0.007732	0.04975	0.03732	NOTCH1/LGMN/PRKD2/CXCL13/HSPB1/RAB13/FGF18/KDR/VEGFA/P2RX4	10
BP	GO:0043457	regulation of cellular respiration	10/2619	31/18670	0.007732	0.04975	0.03732	SNCA/CBFA2T3/PINK1/IDE/IFNG/CCNB1/TRAP1/HIF1A/CDK1/PIK3CA	10
BP	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	10/2619	31/18670	0.007732	0.04975	0.03732	FBXW7/SOS1/ADAM17/EGF/GPER1/AGT/EREG/HIP1R/NUP62/NCF1	10
BP	GO:0071539	protein localization to centrosome	10/2619	31/18670	0.007732	0.04975	0.03732	GSK3B/C2CD3/SPAG5/BBS4/DCTN2/PCM1/GOLGB1/KIAA0753/SNX10/NUP62	10
BP	GO:0002449	lymphocyte mediated immunity	66/2619	352/18670	0.007824	0.05029	0.03772	C7/HLA-C/PARP3/TNFRSF1B/RASGRP1/TFRC/IL27RA/ERCC1/CLU/NBN/MALT1/HLA-F/HLA-G/MICB/IL7R/HLA-A/RAB27A/SUSD4/IL4R/PTPRC/RFTN1/CD8A/SLAMF7/THOC1/HLA-B/HLA-E/HFE/IGLV1-44/PRF1/BTN3A3/IGHM/GZMB/CD96/CD28/DENND1B/CRTAM/CFI/CD40/GCNT3/TCIRG1/CD81/TRBC1/CR1/CD27/VAMP7/IL6/XCL1/SLC11A1/CD19/HLA-DQB1/TNFSF4/HMGB1/C4BPB/BATF/IGLL5/ULBP2/IGLC1/MBL2/EMP2/CEBPG/BCL10/IL13RA2/TLR8/CCR2/FBXO38/CD40LG	66
BP	GO:0050684	regulation of mRNA processing	30/2619	137/18670	0.007933	0.05091	0.03818	SRPK1/HNRNPA2B1/CIRBP/CELF2/MBNL3/KHDRBS3/BARD1/SART3/PRDX6/FAM172A/CELF1/HNRNPK/CPSF7/JMJD6/RBM15/TIA1/CCNB1/SFSWAP/SRSF4/HNRNPA1/SRSF8/RBM19/SREK1/YTHDC1/NCBP2/DAZAP1/SON/SLTM/CDK9/NUP98	30
BP	GO:0051781	positive regulation of cell division	21/2619	87/18670	0.007951	0.05091	0.03818	CDC25B/PTN/ECT2/PGF/THBS4/BTC/RACGAP1/HTR2B/CDC14A/CAT/EREG/PDGFB/AURKB/ZNF16/VEGFA/SSTR5/SPAST/YBX1/FGF5/NUP62/VEGFB	21
BP	GO:0051057	positive regulation of small GTPase mediated signal transduction	18/2619	71/18670	0.007952	0.05091	0.03818	NOTCH1/JAK2/RASGRP1/STK19/SOS1/SHOC2/ARRB1/F2R/NTRK1/AUTS2/IGF1/MAP4K4/AKAP13/MAPRE2/COL3A1/KRAS/GPR4/EPOR	18
BP	GO:0071479	cellular response to ionizing radiation	18/2619	71/18670	0.007952	0.05091	0.03818	SFRP1/ECT2/NIPBL/ATR/CHEK2/ATM/CRYAB/EGR1/NAMPT/RAD1/NET1/WRN/IFI16/RAD9A/CDKN1A/TSPYL5/HSPA5/HMGA2	18
BP	GO:2000377	regulation of reactive oxygen species metabolic process	40/2619	195/18670	0.007967	0.05093	0.0382	GCH1/JAK2/SLC18A2/FBLN5/SNCA/CLU/SMAD3/DDAH1/RAB27A/CFLAR/PID1/EGFR/PINK1/CX3CR1/INSR/BIRC2/CRYAB/TUSC2/FOXM1/DDAH2/IFNG/SIRT3/AGT/ASS1/TSPO/RAC2/AKR1C3/TYROBP/PDGFB/TRAP1/P2RX4/SOD1/HBB/HIF1A/PRDX2/ATP2B4/MPV17/CDKN1A/EIF6/PTK2B	40
BP	GO:0030203	glycosaminoglycan metabolic process	34/2619	160/18670	0.00798	0.05093	0.0382	FUCA1/GPC5/NDNF/UST/GUSB/ANGPT1/IL15/FOXC1/HGF/SDC1/B4GALT2/EGF/PIM1/EXT2/ITIH4/HMMR/NAGLU/CD44/CLN6/NFKB1/HEXA/ST3GAL2/CHST15/EXTL2/B4GALT7/PDGFB/SPOCK2/HAS2/VCAN/SGSH/CHST12/KERA/ARSB/B4GALT3	34
BP	GO:0032680	regulation of tumor necrosis factor production	34/2619	160/18670	0.00798	0.05093	0.0382	TNFAIP3/IRAK3/TREM2/JAK2/RASGRP1/IL27RA/RIPK2/ANGPT1/CLU/SLAMF1/SYT11/PTPRC/LILRA2/UBE2J1/CX3CR1/HLA-E/ARHGEF2/PTPN22/HSPB1/IFNG/TSPO/IGF1/GHSR/AXL/TYROBP/HMGB1/NOD2/MAPKAPK2/LPL/AKAP8/CD2/NOD1/CCR2/TWIST1	34
BP	GO:0002703	regulation of leukocyte mediated immunity	41/2619	201/18670	0.008039	0.05125	0.03844	HLA-C/PARP3/TNFRSF1B/DNASE1L3/RASGRP1/TFRC/IL27RA/MALT1/HLA-F/HLA-G/MICB/IL7R/HLA-A/IL4R/PTPRC/THOC1/HLA-B/HLA-E/HFE/CD96/CD28/CRTAM/FGR/CD40/FOXF1/CD81/CR1/RAC2/VAMP7/IL6/XCL1/TNFSF4/HMGB1/C4BPB/NOD2/ULBP2/DDX1/DDX21/IL13RA2/CCR2/FBXO38	41
BP	GO:0009119	ribonucleoside metabolic process	23/2619	98/18670	0.00807	0.0514	0.03856	NME4/NME7/GAMT/PEMT/ENTPD4/IMPDH2/NT5C2/NME5/ADK/ADA/APOBEC3C/MOCS2/DGUOK/NME3/PNP/APOBEC3B/GUK1/AHCY/CTPS1/MPP1/TJP2/NT5E/AMPD3	23
BP	GO:0016125	sterol metabolic process	35/2619	166/18670	0.008141	0.05164	0.03873	CYB5R1/CEBPA/LIPC/LBR/CH25H/PMVK/EPHX2/ERLIN2/APOL1/APOE/FDX1/CYP11A1/RXRA/CYP7B1/SNX17/SC5D/CAT/CLN6/APOC1/MBTPS1/APOL2/LIPA/DHCR24/DHCR7/KPNB1/NFE2L1/SOD1/PRKAA1/CYB5R3/ACAA2/LIMA1/NPC1/NFYC/LMF1/MVK	35
BP	GO:0006869	lipid transport	68/2619	365/18670	0.008143	0.05164	0.03873	NFKBIA/NME4/LIPC/APOLD1/APOL3/STOML1/CLU/SIGMAR1/OSBPL3/APOM/PLA2G2D/SERPINA5/ATP8B1/APOL1/SLC27A6/RBP4/ABCC4/ABCA8/GRAMD1C/EGF/APOL6/TNFRSF11A/APOE/GULP1/ABCA3/SLC27A5/RXRA/PITPNC1/OSBPL8/TMEM30A/APOO/HNRNPK/PCTP/PPARG/UGCG/SLCO3A1/NFKB1/APOC1/AGT/ABCC1/TSPO/NR1H2/VAMP7/APOL2/SCP2/ABCA2/GM2A/ATP8A1/P2RX4/PLA2R1/ABCA11P/ATP11B/NCOR1/ABCB1/TMF1/NMB/TAC1/GDF9/ATP10A/GAL/PLIN2/CRY1/LIMA1/FABP3/AKR1C4/NPC1/PSAP/STARD7	68
BP	GO:0003012	muscle system process	84/2619	465/18670	0.008166	0.05164	0.03873	SGCA/DYSF/NOTCH1/SPHK1/JARID2/SCN1B/ATP1B1/TNFRSF1B/SNTA1/FXYD1/IGFBP5/TACR2/GAMT/MYL6B/SRI/SMAD3/KCNQ1/IL15/TMOD1/CFLAR/CD38/EZH2/GTF2IRD1/STC1/ADA/SSPN/MYOM2/KIT/BIN1/HSPB6/NOL3/HTR2B/EHD3/ASPH/ROCK1/KCNJ2/MYL3/GPER1/CXCR4/TAZ/CRYAB/F2R/ADRB2/RGS4/CHRNA3/GATM/AGT/CHUK/CTDP1/IGF1/COMP/NOS3/TMOD2/GHSR/HSBP1/MYOC/SORBS2/PIN1/P2RX4/PLCE1/MYL4/CHRNB1/PPP3CA/CACNB2/KCNJ8/SOD1/KCNN2/GAA/MYH4/CTTN/ATP2B4/CACNA1D/AKAP13/ITGB5/NDUFS6/SNTB1/FLNA/CDK9/CAMK2B/ATP2B1/NEDD4L/VEGFB/PIK3CA/SORBS1	84
BP	GO:0031293	membrane protein intracellular domain proteolysis	7/2619	18/18670	0.008173	0.05164	0.03873	ADAM17/NFKB1/MBTPS1/PSENEN/NGFR/APH1B/APH1A	7
BP	GO:0039535	regulation of RIG-I signaling pathway	7/2619	18/18670	0.008173	0.05164	0.03873	RNF125/BIRC3/PUM2/BIRC2/GPATCH3/DDX60/SEC14L1	7
BP	GO:0045683	negative regulation of epidermis development	7/2619	18/18670	0.008173	0.05164	0.03873	NOTCH1/EZH2/DKK4/FERMT1/HOXA7/SMO/REG3A	7
BP	GO:0051023	regulation of immunoglobulin secretion	7/2619	18/18670	0.008173	0.05164	0.03873	RBP4/HLA-E/CD40/IL6/TNFSF4/XBP1/CD40LG	7
BP	GO:1900221	regulation of amyloid-beta clearance	7/2619	18/18670	0.008173	0.05164	0.03873	TREM2/CLU/LRPAP1/APOE/ROCK1/IFNG/HDAC1	7
BP	GO:0022604	regulation of cell morphogenesis	87/2619	484/18670	0.008206	0.0518	0.03885	GBP1/PTN/PLEKHO1/CDH2/UST/SEMA4D/MYCBP2/MACF1/TNIK/SEMA4A/CDC42EP3/SS18L1/SEMA3A/S100A13/FGF13/TUBB2B/ITSN2/BAIAP2/CDC42SE1/CHN1/NTRK2/NEDD9/APOE/GSK3B/KIT/BRWD1/SEMA4C/EFNA5/RHOF/EPB42/TRAK1/FGR/PARP6/CXCR4/SIPA1L1/SYT17/ZMYM2/CD44/FERMT2/YWHAH/POSTN/PHIP/ARHGEF7/CHRNA3/SEMA3F/KDR/LARP4/VAMP7/RND2/TLX2/MYOC/EPHA4/VEGFA/PLXND1/ARHGAP35/AP1AR/SEMA3E/PPP3CA/CCL13/HAS2/PARVB/ANXA7/CTTN/CIB1/GOLGA4/NGFR/ZMYM6/TRPV2/ATP10A/RHOH/CDKL5/PLXNA1/SYT1/CCL7/FBLN1/CYFIP1/CAPRIN2/FLNA/PTK2B/DSCAM/CAMK2B/ACTR2/CPNE6/MYH10/BCL11A/BDNF/NEDD4L	87
BP	GO:0051785	positive regulation of nuclear division	17/2619	66/18670	0.008254	0.05185	0.03889	SPHK1/NIPBL/BTC/DLGAP5/EGF/INSR/NUSAP1/CD28/SMC5/PHIP/LRP5/IGF1/EREG/PDGFB/PIWIL2/NUP62/DAZL	17
BP	GO:1901607	alpha-amino acid biosynthetic process	17/2619	66/18670	0.008254	0.05185	0.03889	CBS/BHMT2/THNSL2/GAMT/GOT1/SERINC5/GATM/ASS1/PSPH/CPS1/OAT/SRR/ATP2B4/SEPHS1/PYCR1/ALDH18A1/ASNS	17
BP	GO:0050930	induction of positive chemotaxis	6/2619	14/18670	0.008281	0.05185	0.03889	PGF/NTF3/VEGFA/SCG2/CXCL8/VEGFB	6
BP	GO:0070669	response to interleukin-2	6/2619	14/18670	0.008281	0.05185	0.03889	IL2RG/JAK1/PTPN2/IL2RB/STAT5A/PTK2B	6
BP	GO:0070672	response to interleukin-15	6/2619	14/18670	0.008281	0.05185	0.03889	IL15RA/IL15/IL2RG/JAK1/IL2RB/STAT5A	6
BP	GO:1901070	guanosine-containing compound biosynthetic process	6/2619	14/18670	0.008281	0.05185	0.03889	NME4/NME7/IMPDH2/NME5/NME3/GUK1	6
BP	GO:1901722	regulation of cell proliferation involved in kidney development	6/2619	14/18670	0.008281	0.05185	0.03889	CFLAR/BMP4/MYC/EGR1/PDGFB/IL6R	6
BP	GO:2000345	regulation of hepatocyte proliferation	6/2619	14/18670	0.008281	0.05185	0.03889	TNFAIP3/PTN/FBXW7/CFLAR/MED1/XBP1	6
BP	GO:0034314	Arp2/3 complex-mediated actin nucleation	11/2619	36/18670	0.008339	0.05206	0.03905	IQGAP2/ACTR3B/ARPC1A/FCHSD2/ACTR3/MAGEL2/AP1AR/ARPC5L/HIP1R/CYFIP1/ACTR2	11
BP	GO:0051031	tRNA transport	11/2619	36/18670	0.008339	0.05206	0.03905	NUP160/NUP153/TPR/NUP50/SEC13/RANBP2/NUP210/NUP43/NDC1/NUP98/NUP62	11
BP	GO:0071392	cellular response to estradiol stimulus	11/2619	36/18670	0.008339	0.05206	0.03905	SFRP1/CCNA2/CFLAR/NCOA3/EGFR/GPER1/CRHBP/RUVBL2/KAT5/BCL2L2/HNRNPD	11
BP	GO:0048592	eye morphogenesis	32/2619	149/18670	0.008407	0.05243	0.03932	EFEMP1/PTN/DIO3/SOX9/NIPBL/RBP4/AGTPBP1/NTRK2/BMP4/FAT1/BBS4/NAGLU/ROM1/ARID1A/LRP5/PRKCI/PRDM1/VEGFA/ALDH1A3/TSKU/TENM3/RS1/IRX5/PHACTR4/HIF1A/SIX3/CEP290/RING1/DSCAM/NRL/TH/TWIST1	32
BP	GO:0002287	alpha-beta T cell activation involved in immune response	16/2619	61/18670	0.008515	0.0529	0.03968	RIPK2/MALT1/RORA/SEMA4A/IL4R/GPR183/LEF1/PTGER4/RC3H2/RELB/IFNG/LY9/IL6/TNFSF4/HMGB1/BATF	16
BP	GO:0002293	alpha-beta T cell differentiation involved in immune response	16/2619	61/18670	0.008515	0.0529	0.03968	RIPK2/MALT1/RORA/SEMA4A/IL4R/GPR183/LEF1/PTGER4/RC3H2/RELB/IFNG/LY9/IL6/TNFSF4/HMGB1/BATF	16
BP	GO:0006879	cellular iron ion homeostasis	16/2619	61/18670	0.008515	0.0529	0.03968	SLC22A17/TFRC/SKP1/SRI/ATP6V0D1/IREB2/HFE/NDFIP1/CYBRD1/FTL/MYC/SLC11A1/CP/SOD1/HIF1A/NEDD8	16
BP	GO:0050864	regulation of B cell activation	38/2619	184/18670	0.008517	0.0529	0.03968	SLAMF8/TNFAIP3/SFRP1/PARP3/CD320/TFRC/IL27RA/TNIP2/PTPRC/CD38/GPR183/ATM/BAD/TNFRSF21/CTLA4/ADA/THOC1/IGHM/CD28/CD40/CD81/PELI1/MZB1/TRBC1/CD27/HMGB3/IL6/TYROBP/CD19/TNFSF4/NOD2/IGLL5/ZFP36L2/IGLC1/CYLD/ID2/CDKN1A/XBP1	38
BP	GO:0003158	endothelium development	29/2619	132/18670	0.008532	0.0529	0.03968	CXCL10/PTN/NOTCH1/PRKD2/APOLD1/TMEM100/ITGAX/NOTCH4/STC1/RAP2C/PECAM1/BMP4/CSNK2B/TNMD/ROCK1/GPX1/PPP1R16B/CXCR4/LAMA5/S1PR1/CDH5/KDR/RBPJ/GSTM3/VEGFA/HOXB5/TJP2/FOXJ2/RAP1B	29
BP	GO:0030518	intracellular steroid hormone receptor signaling pathway	29/2619	132/18670	0.008532	0.0529	0.03968	SFRP1/AR/JAK2/UFSP2/NCOA3/NCOA6/TADA3/CYP7B1/DNAJA1/MED1/KDM3A/PHB/GPER1/ARID1A/YWHAH/LMO3/DAXX/TAF7/BUD31/KAT5/NCOR1/HDAC1/PADI2/RNF14/FHL2/EP300/CRY1/UBR5/KANK2	29
BP	GO:0033273	response to vitamin	22/2619	93/18670	0.008575	0.05299	0.03974	SFRP1/CXCL10/PTN/FOLR1/PEMT/IL15/EGFR/PIM1/STC1/ADA/PENK/MED1/PPARG/CAT/POSTN/FOLR2/TSPO/TRIM24/TYMS/KANK2/STC2/ATP2B1	22
BP	GO:1901184	regulation of ERBB signaling pathway	22/2619	93/18670	0.008575	0.05299	0.03974	LGMN/FBXW7/BTC/SOS1/ADAM17/EGFR/EGF/NCK2/ERBB2/GPER1/PTPN2/CHMP6/CBLB/ARHGEF7/AGT/HBEGF/RBPJ/EREG/RHBDF2/HIP1R/NUP62/NCF1	22
BP	GO:0030593	neutrophil chemotaxis	24/2619	104/18670	0.00858	0.05299	0.03974	CXCL9/DYSF/CXCL10/CCL5/CXCL13/THBS4/CCL18/CXCL11/CXCL2/CCL8/RAC2/XCL1/CCR7/CXCL3/CXCR2/CCL13/IL1RN/PIK3CD/MPP1/S100A12/LGALS3/CXADR/CCL7/CXCL8	24
BP	GO:0098732	macromolecule deacylation	24/2619	104/18670	0.00858	0.05299	0.03974	BEX4/KDM5A/PRKD2/NIPBL/TADA3/PINK1/MSL3/ING2/ZNHIT1/PHB/NEK3/IFNG/SIRT3/VEGFA/SFPQ/RCOR1/AKAP8/HDAC1/PRKAA1/SAP30/EP300/BAZ2A/MORF4L1/SIRT7	24
BP	GO:1902652	secondary alcohol metabolic process	33/2619	155/18670	0.008608	0.05311	0.03983	CEBPA/LIPC/LBR/CH25H/PMVK/EPHX2/ERLIN2/APOL1/APOE/FDX1/CYP11A1/RXRA/CYP7B1/SNX17/SC5D/CAT/CLN6/APOC1/MBTPS1/APOL2/DHCR24/DHCR7/KPNB1/NFE2L1/SOD1/PRKAA1/CYB5R3/ACAA2/LIMA1/NPC1/NFYC/LMF1/MVK	33
BP	GO:0051346	negative regulation of hydrolase activity	84/2619	466/18670	0.008625	0.05316	0.03987	GCHFR/PTN/MICAL1/IQGAP2/BIRC3/KDM5A/SEMA4D/PROS1/SNCA/LAMP3/HERPUD1/SLPI/SERPINA3/CFLAR/SPOCK1/SERPINA1/HGF/ARL2/SERPINA5/NLE1/CDC42SE1/PTTG1/TIMP2/SERPINE1/CARD8/APLP2/GSK3B/BIRC2/BIRC7/SET/ITIH4/BIN1/MAPK7/SERPINB6/TNFAIP8/RRP1B/NOL3/LEF1/SFI1/TFPI/USP47/ROCK1/GZMA/GPX1/BBS4/CRYAB/ARRB1/CD44/CR1/CD27/APOC1/AGT/PTPRN2/NOS3/SORT1/VCPKMT/VEGFA/SERPINA4/PLA2R1/TIMP4/DHCR24/BIRC5/CST7/NAIP/TMED2/COL6A3/SPOCK2/IFI16/NGFR/RAF1/TNFSF14/RHOH/PAK2/ENSA/LGALS3/TIMP1/MNAT1/CST4/RPS6KA1/STYXL1/SERPINF1/ARFGEF1/USP14/RNF34	84
BP	GO:0002381	immunoglobulin production involved in immunoglobulin mediated immune response	15/2619	56/18670	0.008715	0.05351	0.04013	PARP3/TFRC/IL27RA/ERCC1/NBN/PTPRC/THOC1/CD28/CD40/GCNT3/XCL1/HLA-DQB1/TNFSF4/BATF/CD40LG	15
BP	GO:0032615	interleukin-12 production	15/2619	56/18670	0.008715	0.05351	0.04013	IRAK3/IRF1/RIPK2/SLAMF1/HLA-G/IDO1/CD40/NFKB1/IFNG/MAPK11/TNFSF4/HMGB1/CCR7/TLR8/CD40LG	15
BP	GO:0060688	regulation of morphogenesis of a branching structure	15/2619	56/18670	0.008715	0.05351	0.04013	SIX1/SFRP1/AR/SOX9/PGF/HGF/RXRA/BMP4/AGT/SIX2/VEGFA/MAGED1/FKBPL/SMO/BCL11A	15
BP	GO:0090183	regulation of kidney development	15/2619	56/18670	0.008715	0.05351	0.04013	SIX1/STAT1/SOX9/CFLAR/PRKX/BMP4/AGT/SIX2/MYC/EGR1/PDGFB/VEGFA/MAGED1/IL6R/SMO	15
BP	GO:0008584	male gonad development	30/2619	138/18670	0.00881	0.05373	0.0403	HOXA11/SFRP1/NUPR1/AR/HOXA10/KDM5A/SOX9/ERCC1/ASPM/SDC1/SEMA3A/ARID4B/INSR/KIT/ING2/PLEKHA1/NTRK1/ZFPM2/RAB13/NASP/AKR1C3/ATRX/UBB/ARID4A/TMF1/MEA1/BCL2L2/PATZ1/SGPL1/FLNA	30
BP	GO:0016575	histone deacetylation	19/2619	77/18670	0.008821	0.05373	0.0403	KDM5A/PRKD2/NIPBL/TADA3/PINK1/MSL3/ING2/ZNHIT1/PHB/SIRT3/VEGFA/SFPQ/RCOR1/AKAP8/HDAC1/SAP30/BAZ2A/MORF4L1/SIRT7	19
BP	GO:2000779	regulation of double-strand break repair	19/2619	77/18670	0.008821	0.05373	0.0403	PARP3/SMCHD1/CHEK1/TRIP12/ZNF365/DDX11/MMS19/DEK/SETMAR/FOXM1/PML/UBQLN4/TIMELESS/SETD2/UBR5/ACTR2/HMGA2/WDR70/TWIST1	19
BP	GO:0010811	positive regulation of cell-substrate adhesion	27/2619	121/18670	0.008829	0.05373	0.0403	SFRP1/PTN/NDNF/JAK2/SMAD3/ARL2/ITGA5/NEDD9/GSK3B/ROCK1/FOXF1/CD3E/ARHGEF7/KDR/MAP4K4/MYOC/VEGFA/CCR7/FERMT1/NINJ1/EMID1/SPOCK2/EMP2/HAS2/CIB1/FLNA/PTK2B	27
BP	GO:0043618	regulation of transcription from RNA polymerase II promoter in response to stress	27/2619	121/18670	0.008829	0.05373	0.0403	NOTCH1/PSMB9/CHEK1/NCK2/BACH1/ATF3/MAPK7/PSMC2/PSMB6/ATF6/PSMC3/EGR1/RBPJ/VEGFA/PSMD8/UBB/EGLN3/PSMB5/PSMD10/HIF1A/EP300/CUL2/CEBPB/ATF4/HSPA5/DDIT3/RBL2	27
BP	GO:0046718	viral entry into host cell	27/2619	121/18670	0.008829	0.05373	0.0403	TFRC/SLAMF1/NUP153/EGFR/SIVA1/ITGA5/UVRAG/TNFRSF14/TRIM26/IDE/CCR5/ITGB7/CXCR4/CD81/CR1/TRIM21/AXL/IFITM2/ITGB5/CDK1/FCN1/TYRO3/SLC20A2/CXADR/KPNA3/ANPEP/NPC1	27
BP	GO:0048146	positive regulation of fibroblast proliferation	14/2619	51/18670	0.008833	0.05373	0.0403	SPHK1/CCNA2/NDUFS4/BTC/EGFR/CDK4/AGT/IGF1/CCNB1/MYC/PML/EREG/PDGFB/CDKN1A	14
BP	GO:0048260	positive regulation of receptor-mediated endocytosis	14/2619	51/18670	0.008833	0.05373	0.0403	PLCG2/ANGPT1/CLU/EGF/SERPINE1/NTF3/HFE/MAGI2/SELE/HNRNPK/ARRB1/CD63/VEGFA/HIP1R	14
BP	GO:0002437	inflammatory response to antigenic stimulus	13/2619	46/18670	0.008836	0.05373	0.0403	NOTCH1/RASGRP1/HLA-E/CD28/GPX1/ELANE/CD81/RBPJ/AHCY/HMGB1/CCR7/CXCR2/PNMA1	13
BP	GO:0050706	regulation of interleukin-1 beta secretion	13/2619	46/18670	0.008836	0.05373	0.0403	TNFAIP3/AIM2/RIPK2/LILRA2/NLRP1/CARD8/PML/HMGB1/CCR7/NOD2/LPL/GSDMD/TLR8	13
BP	GO:0001505	regulation of neurotransmitter levels	66/2619	354/18670	0.008879	0.05393	0.04045	GCH1/GCHFR/JAK2/ALDH7A1/SLC18A2/SDS/TACR2/SNCA/CLU/RIMS3/SMAD3/DDAH1/PREPL/RORA/PRKCB/SYT11/SLC29A1/SLC7A11/SYNJ1/COMT/PFN2/MCTP1/CX3CR1/NQO1/GSK3B/INSR/NAALAD2/DPYS/GCAT/HRH3/MOXD1/GPER1/SLC38A1/SYT17/LIN7B/DDAH2/IFNG/RGS4/CHRNA3/HDC/AGT/ASS1/PTPRN2/TSPO/NOS3/SNCAIP/HCRT/ALDH9A1/ADCY1/CPS1/ZNF219/P2RX4/ARL6IP5/VAMP2/CACNB2/HBB/ATP2B4/CACNA1D/HNMT/SYT1/SYN1/PTK2B/RAP1B/NAPA/SLC1A1/TH	66
BP	GO:0032673	regulation of interleukin-4 production	9/2619	27/18670	0.008956	0.0543	0.04073	CD83/HLA-E/LEF1/CD28/CD3E/TNFSF4/PRKCQ/CEBPB/CD40LG	9
BP	GO:0036336	dendritic cell migration	9/2619	27/18670	0.008956	0.0543	0.04073	SLAMF8/CCL5/GPR183/CCR5/CXCR4/HMGB1/CCR7/CXCR2/CCR2	9
BP	GO:0032508	DNA duplex unwinding	25/2619	110/18670	0.009048	0.0548	0.0411	CETN2/SETX/CHD1/CHD8/NBN/RECQL/DNA2/RPA1/DDX11/GINS1/ASCC3/ATRX/UBB/RAD50/TOP2A/DDB2/CHD3/RUVBL2/WRN/DDX1/ERCC2/MNAT1/GTF2H3/RFC2/HMGA1	25
BP	GO:1900407	regulation of cellular response to oxidative stress	21/2619	88/18670	0.009096	0.05504	0.04128	GCH1/FBXW7/FBLN5/SLC7A11/HGF/NME5/PINK1/MAPK7/NOL3/GPX1/HSPB1/TRAP1/FUT8/SFPQ/MCL1/SOD1/HIF1A/VNN1/PYCR1/ATF4/PSAP	21
BP	GO:0034340	response to type I interferon	23/2619	99/18670	0.009152	0.05532	0.04149	GBP2/HLA-C/STAT1/IRF1/ADAR/TBK1/HLA-F/HLA-G/HLA-A/TYK2/HLA-B/HLA-E/SAMHD1/JAK1/IRF3/ISG20/PTPN2/EGR1/MMP12/IFITM2/SETD2/OAS2/MYD88	23
BP	GO:0043620	regulation of DNA-templated transcription in response to stress	28/2619	127/18670	0.009174	0.05541	0.04156	NOTCH1/PSMB9/CHEK1/NCK2/BACH1/ATF3/MAPK7/PSMC2/PSMB6/ATF6/PSMC3/EGR1/RBPJ/VEGFA/PSMD8/UBB/EGLN3/PSMB5/PSMD10/HIF1A/EP300/CUL2/RPS6KA1/CEBPB/ATF4/HSPA5/DDIT3/RBL2	28
BP	GO:0051099	positive regulation of binding	37/2619	179/18670	0.009204	0.05553	0.04165	JAK2/RIPK2/NIPBL/FOXC1/EGF/APOE/GSK3B/HFE/BMP4/DDX11/MAPRE3/SPON1/RFNG/PPARG/NMD3/ARRB1/IFNG/PLK2/IGF1/EPHA4/HMBOX1/PLXND1/PIN1/HMGB1/ERCC2/CEBPG/TCF7L2/HIP1R/LARP6/LGALS3/EP300/CAPRIN2/MARK3/CDK9/HMGA2/BDNF/TWIST1	37
BP	GO:0009301	snRNA transcription	18/2619	72/18670	0.009246	0.05573	0.0418	POLR2J/POLR2I/POLR2L/POLR2E/POLR2F/USPL1/INTS6/POLR2C/INTS8/POU2F1/CCNT2/GTF2A2/POLR2G/NABP2/ELL2/CCNK/NCBP2/CDK9	18
BP	GO:1903311	regulation of mRNA metabolic process	61/2619	324/18670	0.009391	0.05655	0.04242	SRPK1/HNRNPA2B1/CIRBP/CELF2/MBNL3/PSMB9/FTO/IGF2BP3/EXOSC7/KHDRBS3/BARD1/PUM2/SART3/PRDX6/SET/HNRNPA0/FAM172A/CELF1/HNRNPK/ZC3HAV1/PSMC2/ROCK1/CPSF7/JMJD6/HSPB1/PRR5L/DCP2/PSMB6/RBM15/TIA1/FASTKD1/CCNB1/PSMC3/SFSWAP/TNPO1/POLR2G/SRSF4/SLC11A1/HNRNPA1/SRSF8/PSMD8/UBB/PSMB5/MAPKAPK2/DND1/ZFP36L2/PSMD10/YBX1/TARDBP/RBM19/SREK1/YTHDC1/NCBP2/DAZAP1/SON/MYD88/SLTM/CDK9/HNRNPD/NUP98/DAZL	61
BP	GO:0007259	JAK-STAT cascade	33/2619	156/18670	0.009485	0.05702	0.04276	AKR1B1/NOTCH1/STAT1/SOCS6/JAK2/CCL5/CRLF1/IL15/PTPRC/NMI/EGF/SOCS1/PECAM1/KIT/CTF1/CD40/PTPN2/F2R/STAT4/IFNG/AGT/IGF1/CRLF3/IL6/ARL2BP/NF2/IL6R/STAT5A/GGNBP2/GHR/ERBB4/SH2B3/CCR2	33
BP	GO:0031023	microtubule organizing center organization	29/2619	133/18670	0.009486	0.05702	0.04276	CETN2/CEP135/NDE1/HAUS3/ARL2/MDM1/CHEK1/SYNE2/UVRAG/CHORDC1/HAUS2/C2CD3/BBS4/PPP1R12A/PLK2/KIF11/PCM1/CHMP2A/BRCA2/CLASP1/CHD3/KIAA0753/ALMS1/CHMP1B/CDK1/KAT2B/CEP63/SPICE1/NUP62	29
BP	GO:0032388	positive regulation of intracellular transport	43/2619	215/18670	0.009594	0.05761	0.04321	ZIC1/ECT2/FIS1/FBXW7/SMAD3/MICALL2/IL4R/PRNP/PINK1/GSK3B/TPR/ERBB2/TMEM30A/SPAG5/ANK3/FGR/CD81/IFNG/PRR5L/PCM1/RAC2/SEC16A/VAMP7/SCP2/DYNC1H1/ATG13/EDEM1/VAMP2/CACNB2/CAMK1/PRKAA1/TARDBP/CIB1/CACNA1D/GTSE1/TCF7L2/NCBP2/SYT1/CEP290/UBL5/FLNA/UBR5/SMO	43
BP	GO:0001894	tissue homeostasis	45/2619	227/18670	0.009621	0.0577	0.04328	TNFAIP3/AKR1B1/NOTCH1/TNFRSF11B/SOX9/TFRC/SERPINA3/CD38/FOXC1/MDM1/PTH1R/RBP4/BARD1/EGFR/LTBP3/TNFRSF11A/RCN3/BBS1/BBS4/TCIRG1/S1PR1/F2R/HSPB1/ADRB2/NOS3/RAC2/IL6/VEGFA/CA2/P2RX4/LIPA/NOD2/IQCB1/SOD1/SNX10/KRT1/CXADR/NCDN/TRIM32/CST4/KRAS/PTK2B/CCR2/SMO/FH	45
BP	GO:0042509	regulation of tyrosine phosphorylation of STAT protein	20/2619	83/18670	0.009628	0.0577	0.04328	JAK2/CCL5/CRLF1/IL15/SOCS1/PECAM1/KIT/CTF1/CD40/PTPN2/IFNG/IGF1/IL6/ARL2BP/NF2/IL6R/GGNBP2/GHR/ERBB4/SH2B3	20
BP	GO:2000573	positive regulation of DNA biosynthetic process	17/2619	67/18670	0.009649	0.05778	0.04333	PRKD2/MAPK3/HNRNPA2B1/ATR/TNKS2/HGF/ATM/MYC/PDGFB/HMBOX1/AURKB/HNRNPA1/PRKCQ/PARM1/PTK2B/HNRNPD/RFC2	17
BP	GO:0046546	development of primary male sexual characteristics	30/2619	139/18670	0.009766	0.05842	0.04382	HOXA11/SFRP1/NUPR1/AR/HOXA10/KDM5A/SOX9/ERCC1/ASPM/SDC1/SEMA3A/ARID4B/INSR/KIT/ING2/PLEKHA1/NTRK1/ZFPM2/RAB13/NASP/AKR1C3/ATRX/UBB/ARID4A/TMF1/MEA1/BCL2L2/PATZ1/SGPL1/FLNA	30
BP	GO:0071706	tumor necrosis factor superfamily cytokine production	35/2619	168/18670	0.009814	0.05865	0.04399	TNFAIP3/IRAK3/TREM2/JAK2/RASGRP1/IL27RA/RIPK2/ANGPT1/CLU/SLAMF1/SYT11/PTPRC/LILRA2/UBE2J1/CX3CR1/HLA-E/ARHGEF2/PTPN22/HSPB1/IFNG/TSPO/IGF1/GHSR/AXL/TYROBP/HMGB1/NOD2/MAPKAPK2/LPL/AKAP8/CD2/NOD1/BCL10/CCR2/TWIST1	35
BP	GO:0032814	regulation of natural killer cell activation	10/2619	32/18670	0.009861	0.05871	0.04403	RASGRP1/IL15/HLA-F/HLA-E/PTPN22/TOX/AXL/TYROBP/PRDM1/IL6R	10
BP	GO:0045589	regulation of regulatory T cell differentiation	10/2619	32/18670	0.009861	0.05871	0.04403	IRF1/BTN2A2/HLA-G/LILRB2/CTLA4/SOCS1/CD28/CR1/IFNG/TNFSF4	10
BP	GO:0046685	response to arsenic-containing substance	10/2619	32/18670	0.009861	0.05871	0.04403	TNFRSF11B/ATF3/UROS/DAXX/HNRNPA1/MKNK2/CPOX/CDKN1A/ATF4/SERPINF1	10
BP	GO:1905508	protein localization to microtubule organizing center	10/2619	32/18670	0.009861	0.05871	0.04403	GSK3B/C2CD3/SPAG5/BBS4/DCTN2/PCM1/GOLGB1/KIAA0753/SNX10/NUP62	10
BP	GO:0070507	regulation of microtubule cytoskeleton organization	38/2619	186/18670	0.01015	0.0604	0.0453	PARP3/STMN2/SNCA/ARL2/MDM1/CHEK1/FGF13/TPX2/GSK3B/CHORDC1/TPR/EFNA5/MAPRE3/SPAG5/ARHGEF2/DRG1/CDH5/PLK2/KIF11/CHMP2A/TAOK1/CLASP1/DYNC1H1/SPAST/KATNB1/ALMS1/SMC1A/AKAP9/PRKAA1/CYLD/RANGRF/CIB1/CHMP1B/TACC3/KAT2B/MAPRE2/SPICE1/NUP62	38
BP	GO:0036037	CD8-positive, alpha-beta T cell activation	8/2619	23/18670	0.01022	0.06063	0.04548	IRF1/RUNX3/HLA-E/SOCS1/HFE/XCL1/SATB1/TNFSF8	8
BP	GO:0051043	regulation of membrane protein ectodomain proteolysis	8/2619	23/18670	0.01022	0.06063	0.04548	TNFRSF1B/TIMP2/APOE/ROCK1/IFNG/TIMP4/TIMP1/LRIG2	8
BP	GO:0060055	angiogenesis involved in wound healing	8/2619	23/18670	0.01022	0.06063	0.04548	TNFAIP3/NDNF/SERPINE1/GPX1/CXCR4/PIK3CB/XBP1/GPR4	8
BP	GO:0043112	receptor metabolic process	39/2619	192/18670	0.01023	0.06063	0.04548	LGMN/JAK2/TFRC/PLCG2/SEC24A/ANGPT1/SNCA/USP46/LRPAP1/EGF/UVRAG/APOE/NTF3/AP2M1/CNPY2/HTR2B/EHD3/MAGI2/SELE/HNRNPK/PPARG/ARRB1/CD81/VAMP3/IFNG/TBC1D16/CD63/TRAT1/GPRASP1/VEGFA/FUT8/AP1AR/CXCR2/OPTN/HIF1A/HOXA5/HDAC1/RAB11B/CXCL8	39
BP	GO:0010965	regulation of mitotic sister chromatid separation	15/2619	57/18670	0.01033	0.06074	0.04556	ATM/DLGAP5/PTTG1/TPR/BUB1B/LCMT1/NDC80/CENPE/CCNB1/CDC20/AURKB/TACC3/PTTG2/CENPF/FBXO5	15
BP	GO:0031294	lymphocyte costimulation	15/2619	57/18670	0.01033	0.06074	0.04556	CD320/CTLA4/TNFRSF14/CD28/MAP3K8/CD81/CD3E/LCK/EFNB1/TNFSF4/CCR7/TNFSF14/PAK2/CD40LG/PIK3CA	15
BP	GO:0043525	positive regulation of neuron apoptotic process	15/2619	57/18670	0.01033	0.06074	0.04556	NUPR1/FIS1/FBXW7/ATM/MAP3K11/PRNP/NQO1/UBE2M/TYROBP/CASP9/PIN1/MCL1/ATF2/ATF4/DDIT3	15
BP	GO:0045981	positive regulation of nucleotide metabolic process	15/2619	57/18670	0.01033	0.06074	0.04556	NUPR1/TREM2/PID1/PINK1/INSR/PFKFB3/TAZ/GUCA1A/IFNG/IGF1/NOS3/CCNB1/HIF1A/PRKAA1/CDK1	15
BP	GO:0051310	metaphase plate congression	15/2619	57/18670	0.01033	0.06074	0.04556	SPAG5/CDCA8/CHMP6/NDC80/CENPE/CHMP2A/CCNB1/MIS12/DYNC1H1/KPNB1/CHMP1B/CENPC/SPICE1/CENPF/NUP62	15
BP	GO:1900544	positive regulation of purine nucleotide metabolic process	15/2619	57/18670	0.01033	0.06074	0.04556	NUPR1/TREM2/PID1/PINK1/INSR/PFKFB3/TAZ/GUCA1A/IFNG/IGF1/NOS3/CCNB1/HIF1A/PRKAA1/CDK1	15
BP	GO:0002573	myeloid leukocyte differentiation	41/2619	204/18670	0.01034	0.06074	0.04556	SFRP1/CEBPA/TREM2/TFRC/FBXW7/LBR/IL15/TCTA/CBFA2T3/GPR183/CTNNBIP1/TNFRSF11A/IREB2/KIT/BMP4/LEF1/MED1/DHRS7B/PPARG/PTPN2/TCIRG1/CD81/RELB/IFNG/TRIB1/MYC/RBPJ/TYROBP/VEGFA/CA2/CCR7/BATF/SNX10/IFI16/PIK3CD/CREB1/ID2/GLO1/HOXA7/CEBPB/SBNO2	41
BP	GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	23/2619	100/18670	0.01035	0.06074	0.04556	HLA-C/TFRC/IL27RA/RIPK2/MALT1/HLA-F/HLA-G/HLA-A/PTPRC/ADA/HLA-B/HLA-E/CD28/CD40/CD81/IL6/XCL1/SLC11A1/TNFSF4/PRKCQ/IL6R/CCR2/FBXO38	23
BP	GO:0034446	substrate adhesion-dependent cell spreading	23/2619	100/18670	0.01035	0.06074	0.04556	GBP1/AKIP1/LAMC3/MICALL2/MERTK/NEDD9/EFNA5/ITGB7/LAMA5/FERMT2/POSTN/VAMP3/ARHGEF7/MYOC/AXL/AP1AR/HAS2/PARVB/CIB1/TYRO3/FBLN1/FLNA/FZD7	23
BP	GO:0061640	cytoskeleton-dependent cytokinesis	23/2619	100/18670	0.01035	0.06074	0.04556	ECT2/ARL3/RACGAP1/ACTR3/DCTN3/NUSAP1/CEP55/ROCK1/ANK3/BBS4/CHMP6/CHMP2A/KIF4A/BRCA2/AURKB/USP8/SPAST/CHMP1B/SON/KIF20A/ACTR2/MYH10/NUP62	23
BP	GO:0032885	regulation of polysaccharide biosynthetic process	11/2619	37/18670	0.01039	0.06096	0.04573	ENPP1/EGF/GSK3B/INSR/DYRK2/NFKB1/IGF1/PDGFB/HAS2/PASK/SORBS1	11
BP	GO:0010959	regulation of metal ion transport	72/2619	394/18670	0.01042	0.06102	0.04577	CXCL9/DYSF/SIK1/CXCL10/SCN1B/ATP1B1/TREM2/SNTA1/FXYD1/CCL5/PLCG2/SNCA/SRI/KCNQ1/CXCL11/LILRB2/FGF14/FXYD6/LILRA2/NETO2/EGF/PRNP/STC1/HFE/BIN1/EHD3/KLHL24/KCNJ2/ANK3/GPER1/CXCR4/TSPAN13/F2R/ADRB2/YWHAH/IFNG/RGS4/CD63/AGT/TSPO/NOS3/S100A1/HCRT/PML/SLC31A2/PDGFB/XCL1/CD19/P2RX4/CALCR/HOMER3/VAMP2/CACNB2/REM1/KCNN2/LIME1/AKAP9/RANGRF/ATP2B4/CACNA1D/TRPV2/GAL/LGALS3/HSPA2/FLNA/PTK2B/ATF4/CAMK2B/STC2/ATP2B1/NEDD4L/DPP6	72
BP	GO:0001764	neuron migration	33/2619	157/18670	0.01043	0.06102	0.04577	NDNF/NDE1/NIPBL/ASPM/SPOCK1/DDIT4/SEMA3A/FGF13/TUBB2B/NDN/NTRK2/ARHGEF2/FZD3/BBS4/PEX7/CXCR4/GPM6A/AUTS2/PCM1/ELP3/AXL/VEGFA/USP9X/CDKL5/CCKAR/ERBB4/COL3A1/FLNA/CAMK2B/MYH10/LRIG2/TWIST1/SATB2	33
BP	GO:0031570	DNA integrity checkpoint	33/2619	157/18670	0.01043	0.06102	0.04577	TOPBP1/NBN/RFWD3/ATR/CRADD/CHEK2/CHEK1/ATM/DNA2/THOC1/PEA15/DONSON/SETMAR/PLK2/CCNB1/TAOK1/PML/DTL/TOP2A/RAD1/TIMELESS/TAOK3/BABAM1/GTSE1/CDK1/RAD9A/CDKN1A/ATF2/EP300/CEP63/CRY1/HMGA2/RBL2	33
BP	GO:0030111	regulation of Wnt signaling pathway	67/2619	363/18670	0.01054	0.0616	0.0462	TNFAIP3/WIF1/SFRP1/NOTCH1/FOLR1/WNT5B/GPC5/CDH2/SOX9/IGFBP2/CHD8/MACF1/SMAD3/ASPM/CBY1/TNKS2/PSMB9/NLE1/EGFR/EGF/CTNNBIP1/ZBED2/APOE/GSK3B/MDFI/IGFBP4/WNT11/PLEKHA4/LEF1/PSMC2/USP47/USP34/NFKB1/GRB10/PSMB6/WLS/PSMC3/EGR1/RBPJ/CSNK1A1/DKK4/PIN1/USP8/PSMD8/CXXC4/TSKU/LGR5/FERMT1/PSMB5/FRAT1/CSNK1E/NLK/RUVBL2/PFDN5/PSMD10/TLE3/HDAC1/CYLD/SIX3/TCF7L2/TLE2/FZD6/CAPRIN2/UBR5/FZD7/DDIT3/HMGXB4	67
BP	GO:0060147	regulation of posttranscriptional gene silencing	26/2619	117/18670	0.0106	0.06173	0.0463	ADAR/POLR2J/POLR2I/NUP160/POLR2L/NUP153/EGFR/POLR2E/POLR2F/PUM2/TPR/BMP4/NUP50/PPARG/POLR2C/SEC13/RANBP2/POLR2G/NUP210/DND1/PPP3CA/NCOR1/NUP43/NDC1/NUP98/NUP62	26
BP	GO:0060966	regulation of gene silencing by RNA	26/2619	117/18670	0.0106	0.06173	0.0463	ADAR/POLR2J/POLR2I/NUP160/POLR2L/NUP153/EGFR/POLR2E/POLR2F/PUM2/TPR/BMP4/NUP50/PPARG/POLR2C/SEC13/RANBP2/POLR2G/NUP210/DND1/PPP3CA/NCOR1/NUP43/NDC1/NUP98/NUP62	26
BP	GO:0032640	tumor necrosis factor production	34/2619	163/18670	0.0106	0.06173	0.0463	TNFAIP3/IRAK3/TREM2/JAK2/RASGRP1/IL27RA/RIPK2/ANGPT1/CLU/SLAMF1/SYT11/PTPRC/LILRA2/UBE2J1/CX3CR1/HLA-E/ARHGEF2/PTPN22/HSPB1/IFNG/TSPO/IGF1/GHSR/AXL/TYROBP/HMGB1/NOD2/MAPKAPK2/LPL/AKAP8/CD2/NOD1/CCR2/TWIST1	34
BP	GO:1903555	regulation of tumor necrosis factor superfamily cytokine production	34/2619	163/18670	0.0106	0.06173	0.0463	TNFAIP3/IRAK3/TREM2/JAK2/RASGRP1/IL27RA/RIPK2/ANGPT1/CLU/SLAMF1/SYT11/PTPRC/LILRA2/UBE2J1/CX3CR1/HLA-E/ARHGEF2/PTPN22/HSPB1/IFNG/TSPO/IGF1/GHSR/AXL/TYROBP/HMGB1/NOD2/MAPKAPK2/LPL/AKAP8/CD2/NOD1/CCR2/TWIST1	34
BP	GO:0006605	protein targeting	78/2619	432/18670	0.01062	0.06174	0.04631	MICALL1/ZDHHC18/FIS1/FBXW7/VPS13C/ECI2/PEX10/CLU/MICALL2/VPS37C/EPHX2/ACOX2/RAB27A/NDUFA13/PEX19/ZFYVE16/DECR2/TIMM10/ZDHHC4/DDO/PRNP/PINK1/PHYH/GNPTAB/IDE/HMGCL/ERBB2/TRAK1/VTI1B/ECH1/RPS8/RPL12/ANK3/PEX7/SPCS3/CAT/PEX2/RPS11/PRKCI/TSPO/RAC2/VAMP7/SCP2/RPL10A/ZDHHC3/AP4S1/RPS5/UBB/ATG13/HOMER3/SEC61A2/PEX12/PEX14/KATNB1/SRP54/USP9X/ACOX1/RPL27A/AGPS/PRKAA1/SSR2/CIB1/RPL8/PMM1/RPL19/ACOT8/MPV17/CRAT/SAMM50/MIPEP/NUCB1/UBL5/HSPA5/GABARAP/RPL35A/AP4M1/RPLP0/NCF1	78
BP	GO:0002639	positive regulation of immunoglobulin production	12/2619	42/18670	0.01064	0.06174	0.04631	TFRC/IL4R/PTPRC/RBP4/HLA-E/CD28/CD40/MZB1/IL6/XCL1/TNFSF4/XBP1	12
BP	GO:0017145	stem cell division	12/2619	42/18670	0.01064	0.06174	0.04631	NOTCH1/ASPM/NCOA3/FGF13/NAP1L2/KIT/ING2/ARHGEF2/LEF1/ZFP36L2/DCT/FZD7	12
BP	GO:0031057	negative regulation of histone modification	12/2619	42/18670	0.01064	0.06174	0.04631	MTF2/JARID2/KDM5A/SNCA/DNMT1/TRIP12/SET/ZNF451/KDM3A/TAF7/UBR5/TWIST1	12
BP	GO:0030261	chromosome condensation	13/2619	47/18670	0.01068	0.06184	0.04638	NIPBL/NUSAP1/GPER1/NCAPH/BANF1/CCNB1/NCAPG/TOP2A/SMC4/AKAP8/DFFB/CDK1/HMGA2	13
BP	GO:1903580	positive regulation of ATP metabolic process	13/2619	47/18670	0.01068	0.06184	0.04638	NUPR1/TREM2/PID1/PINK1/INSR/PFKFB3/TAZ/IFNG/IGF1/CCNB1/HIF1A/PRKAA1/CDK1	13
BP	GO:0032945	negative regulation of mononuclear cell proliferation	18/2619	73/18670	0.0107	0.06185	0.04639	BTN2A2/HLA-G/PLA2G2D/LILRB2/ATM/TNFRSF21/CTLA4/IDO1/PRNP/TNFRSF14/BMP4/ERBB2/PELI1/TYROBP/XCL1/GLMN/GAL/CEBPB	18
BP	GO:0050672	negative regulation of lymphocyte proliferation	18/2619	73/18670	0.0107	0.06185	0.04639	BTN2A2/HLA-G/PLA2G2D/LILRB2/ATM/TNFRSF21/CTLA4/IDO1/PRNP/TNFRSF14/BMP4/ERBB2/PELI1/TYROBP/XCL1/GLMN/GAL/CEBPB	18
BP	GO:0034620	cellular response to unfolded protein	30/2619	140/18670	0.0108	0.06227	0.0467	ATP6V0D1/KLHDC3/HERPUD1/KDELR3/NCK2/YIF1A/ATF3/CREB3/DDX11/TATDN2/PTPN2/EXTL2/DAXX/MBTPS1/ATF6/TBL2/HSPA6/EDEM1/OPTN/DNAJC3/CXXC1/EP300/XBP1/HSPA2/CXCL8/ATF4/HSPA5/ASNS/STC2/DDIT3	30
BP	GO:0042737	drug catabolic process	30/2619	140/18670	0.0108	0.06227	0.0467	FAH/HPD/SDS/QDPR/SNCA/PCBD1/GNPDA1/COMT/ADA/GPX3/PRDX6/DPYS/IDE/GCAT/ASRGL1/GSTZ1/PXDN/GPX1/MOXD1/CAT/OXCT1/ACAT1/PCK2/SULT1A2/HBB/PRDX2/FMO4/NT5E/AMPD3/ALDH3B1	30
BP	GO:0072073	kidney epithelium development	30/2619	140/18670	0.0108	0.06227	0.0467	SIX1/HOXA11/SFRP1/NOTCH1/STAT1/SOX9/CRLF1/PGF/SMAD3/FOXC1/SDC1/CTNNBIP1/PECAM1/BMP4/WNT11/MAGI2/KLHL3/LAMA5/CAT/ACAT1/AGT/SIX2/MYC/EPHA4/VEGFA/MAGED1/CXCR2/SMO/KANK2/PODXL	30
BP	GO:0042136	neurotransmitter biosynthetic process	24/2619	106/18670	0.01089	0.06271	0.04703	GCH1/GCHFR/JAK2/CLU/SMAD3/DDAH1/RORA/CX3CR1/NQO1/INSR/MOXD1/DDAH2/IFNG/HDC/AGT/ASS1/TSPO/NOS3/ALDH9A1/P2RX4/HBB/ATP2B4/PTK2B/TH	24
BP	GO:0022408	negative regulation of cell-cell adhesion	37/2619	181/18670	0.01098	0.06316	0.04737	IRF1/SOCS6/JAK2/BTN2A2/HLA-G/PLA2G2D/IL4R/LILRB2/TNFRSF21/CTLA4/IDO1/PRNP/RUNX3/TNFRSF14/SOCS1/HFE/MAPK7/LAX1/BMP4/ERBB2/PTPN22/PTPN2/RC3H2/PELI1/ASS1/XCL1/VEGFA/TNFSF4/HMGB1/GLMN/PRDX2/IL1RN/NF2/LGALS3/SH2B3/CEBPB/PODXL	37
BP	GO:0002702	positive regulation of production of molecular mediator of immune response	22/2619	95/18670	0.01105	0.06329	0.04747	TFRC/MAPK3/MALT1/HLA-F/HLA-G/IL4R/PTPRC/RBP4/TNFRSF14/HLA-E/CD28/CD40/CD81/MZB1/IL6/XCL1/TNFSF4/NOD2/DDX1/DDX21/BCL10/XBP1	22
BP	GO:0060337	type I interferon signaling pathway	22/2619	95/18670	0.01105	0.06329	0.04747	GBP2/HLA-C/STAT1/IRF1/ADAR/TBK1/HLA-F/HLA-G/HLA-A/TYK2/HLA-B/HLA-E/SAMHD1/JAK1/IRF3/ISG20/PTPN2/EGR1/MMP12/IFITM2/OAS2/MYD88	22
BP	GO:0071357	cellular response to type I interferon	22/2619	95/18670	0.01105	0.06329	0.04747	GBP2/HLA-C/STAT1/IRF1/ADAR/TBK1/HLA-F/HLA-G/HLA-A/TYK2/HLA-B/HLA-E/SAMHD1/JAK1/IRF3/ISG20/PTPN2/EGR1/MMP12/IFITM2/OAS2/MYD88	22
BP	GO:0042542	response to hydrogen peroxide	31/2619	146/18670	0.01105	0.06329	0.04747	TNFAIP3/SPHK1/SETX/STAT1/MAP3K5/ECT2/SIGMAR1/HGF/SDC1/EZH2/BAD/PINK1/NQO1/ADA/MAPK7/PLEKHA1/GPX1/CRYAB/CAT/ANKZF1/IL6/AXL/TRAP1/SOD1/HBB/NET1/PRKAA1/CDK1/PYCR1/PTK2B/PSAP	31
BP	GO:0051384	response to glucocorticoid	31/2619	146/18670	0.01105	0.06329	0.04747	IGFBP2/GOT1/CFLAR/DDIT4/SDC1/HSD11B2/BAD/EGFR/STC1/ABCA3/ASS1/PAPPA/IL6/GHSR/CPS1/PCK2/CASP9/USP8/CALCR/SSTR5/ZFP36L2/IL1RN/TYMS/AKAP13/HNMT/CDKN1A/KRAS/SERPINF1/IL22/ATP2B1/TH	31
BP	GO:0010812	negative regulation of cell-substrate adhesion	17/2619	68/18670	0.01123	0.06416	0.04813	GBP1/NOTCH1/SPOCK1/SERPINE1/ANGPT2/CORO2B/EFNA5/POSTN/MAP4K4/MYOC/MMP12/AP1AR/SEMA3E/NF2/FBLN1/HOXA7/FZD7	17
BP	GO:0019915	lipid storage	17/2619	68/18670	0.01123	0.06416	0.04813	NFKBIA/DYSF/ENPP1/FBXW7/FTO/APOE/MEST/OSBPL8/PPARG/PTPN2/NFKB1/NR1H2/IL6/GM2A/LPL/PLIN2/CRY1	17
BP	GO:0045137	development of primary sexual characteristics	44/2619	223/18670	0.01125	0.06422	0.04817	HOXA11/SFRP1/NUPR1/AR/HOXA10/KDM5A/SOX9/ERCC1/ASPM/FOXC1/SDC1/SEMA3A/ARID4B/ATM/INSR/KIT/ING2/PLEKHA1/ARRB1/NTRK1/ZFPM2/NOS3/RAB13/NASP/ANG/BRCA2/AKR1C3/EREG/ATRX/VEGFA/UBB/IRX5/ARID4A/SOD1/TMF1/MEA1/BCL2L2/GDF9/PATZ1/SGPL1/INHBB/FLNA/CEBPB/HSPA5	44
BP	GO:0031109	microtubule polymerization or depolymerization	25/2619	112/18670	0.01138	0.0648	0.0486	STMN2/TUBG2/SNCA/NDE1/ARL2/FGF13/KIF2A/MAPRE3/ARHGEF2/MAP7D3/CRYAB/KIF18B/DRG1/CDH5/TAOK1/CLASP1/TUBGCP5/SPAST/KATNB1/AKAP9/RANGRF/CIB1/MAPRE2/TUBGCP2/FBXO5	25
BP	GO:0003159	morphogenesis of an endothelium	7/2619	19/18670	0.0114	0.0648	0.0486	CXCL10/PRKD2/ITGAX/BMP4/CSNK2B/CXCR4/RBPJ	7
BP	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway	7/2619	19/18670	0.0114	0.0648	0.0486	PRKD2/PRKCB/ITGA5/GRB10/FGF18/VEGFA/HIF1A	7
BP	GO:0045063	T-helper 1 cell differentiation	7/2619	19/18670	0.0114	0.0648	0.0486	RIPK2/SEMA4A/IL4R/LEF1/RELB/TNFSF4/HMGB1	7
BP	GO:0061154	endothelial tube morphogenesis	7/2619	19/18670	0.0114	0.0648	0.0486	CXCL10/PRKD2/ITGAX/BMP4/CSNK2B/CXCR4/RBPJ	7
BP	GO:0032770	positive regulation of monooxygenase activity	9/2619	28/18670	0.01159	0.06576	0.04932	GCH1/APOE/HTR2B/IFNG/S100A1/HIF1A/NOD1/KRAS/PTK2B	9
BP	GO:0045577	regulation of B cell differentiation	9/2619	28/18670	0.01159	0.06576	0.04932	SLAMF8/SFRP1/BAD/CD27/HMGB3/ZFP36L2/CYLD/ID2/XBP1	9
BP	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	23/2619	101/18670	0.01167	0.0661	0.04958	TREM2/LGMN/HLA-DRB4/SEC24A/KIF2A/AP1B1/RACGAP1/DCTN6/DCTN3/CTSF/AP2M1/CAPZA1/SEC13/DCTN2/CENPE/KIF11/DYNC1I1/KIF4A/KIF15/HLA-DOB/AP1S1/HLA-DQB1/DYNC1H1	23
BP	GO:0055072	iron ion homeostasis	19/2619	79/18670	0.01167	0.0661	0.04958	SLC22A17/TFRC/SKP1/SRI/ATP6V0D1/NEO1/BDH2/IREB2/HFE/NDFIP1/EPB42/CYBRD1/FTL/MYC/SLC11A1/CP/SOD1/HIF1A/NEDD8	19
BP	GO:0046686	response to cadmium ion	16/2619	63/18670	0.01172	0.06634	0.04975	HAAO/MAPK3/ERCC1/GOT1/EGFR/PRNP/KIT/SORD/CAT/DAXX/CHUK/AKR1C3/SOD1/CDK1/NPC1/NCF1	16
BP	GO:0046883	regulation of hormone secretion	51/2619	266/18670	0.01175	0.0664	0.0498	SFRP1/JAK2/CCL5/RPH3AL/TACR2/SRI/SLC25A4/MPC2/CD38/ARL2/RBP4/BAD/EGFR/HFE/EFNA5/RAB11FIP1/GPER1/TCIRG1/ARRB1/HADH/OXCT1/IFNG/ITPR2/CHRNA3/SIRT3/AGT/CRHBP/LRP5/VAMP7/MAP4K4/GHSR/ARL2BP/ABCC8/ANO1/PPP3CA/SSTR5/HIF1A/TMF1/NMB/TARDBP/TAC1/GDF9/CACNA1D/CREB1/GAL/TCF7L2/CCKAR/ENSA/CRY1/INHBB/PASK	51
BP	GO:0014033	neural crest cell differentiation	21/2619	90/18670	0.01179	0.0664	0.0498	SFRP1/FOLR1/SOX9/SEMA4D/MAPK3/SEMA4A/FOXC1/SEMA3A/BMP4/SEMA4C/HTR2B/FAM172A/LAMA5/SEMA3F/EFNB1/SEMA3E/PHACTR4/HIF1A/ERBB4/SMO/TWIST1	21
BP	GO:0030901	midbrain development	21/2619	90/18670	0.01179	0.0664	0.0498	SFRP1/SOS1/CMA1/FZD3/ZNF430/KDM7A/YWHAH/NDRG2/WLS/S100A1/SEC16A/EN1/CXCR2/CSNK1E/RAD1/PADI2/UQCRQ/NDUFS3/FZD6/PLP1/HSPA5	21
BP	GO:0034333	adherens junction assembly	21/2619	90/18670	0.01179	0.0664	0.0498	SFRP1/TRIP6/MACF1/SMAD3/CORO2B/LIMCH1/EFNA5/ROCK1/LAMA5/FERMT2/ARHGEF7/KDR/MAP4K4/CLASP1/MYOC/VEGFA/PTPRK/CTTN/ACTN1/PTK2B/SORBS1	21
BP	GO:0045778	positive regulation of ossification	21/2619	90/18670	0.01179	0.0664	0.0498	PTN/CEBPA/NELL1/NIPBL/SMAD3/ATRAID/HGF/CTNNBIP1/BMP4/OSR2/ADRB2/LRP5/IGF1/IL6/SUCO/TAC1/IL6R/CEBPB/ATP2B1/GDPD2/FBXO5	21
BP	GO:0010821	regulation of mitochondrion organization	37/2619	182/18670	0.01197	0.06643	0.04983	FAM162A/TREM2/FIS1/FBXW7/VPS13C/CLU/MICALL2/HGF/PID1/BAD/PINK1/GSK3B/NOL3/GZMB/TMEM14A/GPX1/PPP1R13B/GPER1/YWHAH/TSPO/IGF1/TP53BP2/KDR/RAC2/ATG13/OPTN/CIDEB/PSMD10/HIF1A/PRKAA1/CTTN/ACAA2/HIP1R/GOLPH3/UBL5/STOML2/CLEC16A	37
BP	GO:0002517	T cell tolerance induction	5/2619	11/18670	0.01197	0.06643	0.04983	HLA-G/LILRB2/IDO1/CD3E/PHLPP1	5
BP	GO:0006183	GTP biosynthetic process	5/2619	11/18670	0.01197	0.06643	0.04983	NME4/NME7/IMPDH2/NME5/NME3	5
BP	GO:0009125	nucleoside monophosphate catabolic process	5/2619	11/18670	0.01197	0.06643	0.04983	NUDT9/NUDT11/DNPH1/NT5E/AMPD3	5
BP	GO:0009151	purine deoxyribonucleotide metabolic process	5/2619	11/18670	0.01197	0.06643	0.04983	ADK/ADA/SAMHD1/DGUOK/GUK1	5
BP	GO:0032494	response to peptidoglycan	5/2619	11/18670	0.01197	0.06643	0.04983	IRAK3/TREM2/RIPK2/IL6/NOD2	5
BP	GO:0033632	regulation of cell-cell adhesion mediated by integrin	5/2619	11/18670	0.01197	0.06643	0.04983	CCL5/CXCL13/ADA/CD3E/PODXL	5
BP	GO:0039532	negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway	5/2619	11/18670	0.01197	0.06643	0.04983	RNF125/TSPAN6/GPATCH3/SEC14L1/RIOK3	5
BP	GO:0045060	negative thymic T cell selection	5/2619	11/18670	0.01197	0.06643	0.04983	PTPRC/CD28/ZAP70/CD3E/CCR7	5
BP	GO:0046501	protoporphyrinogen IX metabolic process	5/2619	11/18670	0.01197	0.06643	0.04983	FECH/IREB2/UROD/UROS/CPOX	5
BP	GO:0046950	cellular ketone body metabolic process	5/2619	11/18670	0.01197	0.06643	0.04983	BDH2/SLC27A5/HMGCL/OXCT1/ACAT1	5
BP	GO:0051024	positive regulation of immunoglobulin secretion	5/2619	11/18670	0.01197	0.06643	0.04983	RBP4/HLA-E/IL6/TNFSF4/XBP1	5
BP	GO:0070213	protein auto-ADP-ribosylation	5/2619	11/18670	0.01197	0.06643	0.04983	PARP12/PARP3/TNKS2/PARP6/PARP8	5
BP	GO:0070757	interleukin-35-mediated signaling pathway	5/2619	11/18670	0.01197	0.06643	0.04983	STAT1/JAK2/IL27RA/JAK1/STAT4	5
BP	GO:0072110	glomerular mesangial cell proliferation	5/2619	11/18670	0.01197	0.06643	0.04983	CFLAR/BMP4/EGR1/PDGFB/IL6R	5
BP	GO:0090042	tubulin deacetylation	5/2619	11/18670	0.01197	0.06643	0.04983	BEX4/TADA3/NEK3/PRKAA1/EP300	5
BP	GO:1901201	regulation of extracellular matrix assembly	5/2619	11/18670	0.01197	0.06643	0.04983	NOTCH1/SOX9/SMAD3/AGT/HAS2	5
BP	GO:0044782	cilium organization	70/2619	384/18670	0.01205	0.0668	0.0501	NOTCH1/CETN2/TCTN1/GALNT11/CEP135/IFT46/TMEM231/CNTRL/ARL3/ATP6V0D1/NDE1/HAUS3/RPGR/CBY1/SYNE2/TCTN3/NME5/ABCC4/ASAP1/IFT52/ATXN10/ACTR3/DCTN3/TMEM80/DYNLRB1/HAUS2/C2CD3/EHD3/MNS1/SFI1/BBS1/BBS4/TTLL1/RABEP2/B9D1/CDC14A/LAMA5/FGFR1OP/DCTN2/TUBA4A/C5orf30/PCM1/SPATA6/CLASP1/TNPO1/SPAG1/CLUAP1/DYNC1H1/IFT140/ARHGAP35/IQCB1/CSNK1E/TTC17/WDR11/SNX10/ALMS1/AKAP9/CYLD/UNC119B/CDK1/VDAC3/CDKL5/IFT22/CEP290/CEP63/FLNA/OFD1/TCTN2/ACTR2/DYNC2LI1	70
BP	GO:0017001	antibiotic catabolic process	15/2619	58/18670	0.01217	0.06715	0.05037	AKR1B10/SNCA/GNPDA1/GPX3/PRDX6/PXDN/GPX1/ESD/CAT/AKR1C3/PCK2/SULT1A2/HBB/PRDX2/ALDH3B1	15
BP	GO:0042093	T-helper cell differentiation	15/2619	58/18670	0.01217	0.06715	0.05037	RIPK2/MALT1/RORA/SEMA4A/IL4R/GPR183/LEF1/PTGER4/RC3H2/RELB/LY9/IL6/TNFSF4/HMGB1/BATF	15
BP	GO:0061900	glial cell activation	15/2619	58/18670	0.01217	0.06715	0.05037	SPHK1/TREM2/JAK2/SNCA/CLU/PTPRC/ATM/EGFR/IFNG/IL6/NAMPT/TYROBP/CST7/TLR8/SMO	15
BP	GO:0042762	regulation of sulfur metabolic process	6/2619	15/18670	0.01219	0.06715	0.05037	PDK2/SNCA/SLC7A11/COMT/GSTZ1/PDK1	6
BP	GO:0042921	glucocorticoid receptor signaling pathway	6/2619	15/18670	0.01219	0.06715	0.05037	NCOA6/PHB/ARID1A/YWHAH/LMO3/CRY1	6
BP	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	6/2619	15/18670	0.01219	0.06715	0.05037	STAT1/JAK2/IFNG/KDR/NAMPT/NOD2	6
BP	GO:2001185	regulation of CD8-positive, alpha-beta T cell activation	6/2619	15/18670	0.01219	0.06715	0.05037	IRF1/RUNX3/HLA-E/SOCS1/HFE/XCL1	6
BP	GO:0098781	ncRNA transcription	24/2619	107/18670	0.01222	0.06729	0.05047	POLR2J/POLR2I/POLR2L/POLR2E/POLR2F/USPL1/DDX11/INTS6/POLR2C/INTS8/POLR1B/POU2F1/CCNT2/GTF2A2/ANG/POLR2G/NABP2/ELL2/CCNK/NCBP2/NPM3/CDK9/SIRT7/GTF3C5	24
BP	GO:0009914	hormone transport	60/2619	322/18670	0.01227	0.06749	0.05062	SFRP1/JAK2/CCL5/RPH3AL/TACR2/SRI/SLC25A4/MPC2/CD38/ARL2/SLC16A2/RBP4/BAD/EGFR/SLCO4A1/HFE/EFNA5/RAB11FIP1/GPER1/TCIRG1/ARRB1/HADH/OXCT1/IFNG/ITPR2/CHRNA3/SIRT3/AGT/PTPRN2/CRHBP/LRP5/VAMP7/MAP4K4/IL6/GHSR/ARL2BP/ABCC8/CPE/ANO1/PPP3CA/SSTR5/LTBP4/HIF1A/TMF1/NMB/IL1RN/TARDBP/TAC1/GDF9/CACNA1D/RAF1/CREB1/GAL/RAB11B/TCF7L2/CCKAR/ENSA/CRY1/INHBB/PASK	60
BP	GO:0048199	vesicle targeting, to, from or within Golgi	18/2619	74/18670	0.01234	0.06774	0.05081	FOLR1/SEC24A/SERPINA1/PPP6R3/SEC22B/SEC13/F8/TRAPPC2L/CNIH1/TRAPPC10/SEC16A/AP1AR/TMED2/TMED9/TMED10/ANKRD28/NAPA/CD59	18
BP	GO:1900076	regulation of cellular response to insulin stimulus	18/2619	74/18670	0.01234	0.06774	0.05081	PTPRE/ENPP1/PRKCB/PID1/CDK4/SOCS1/OSBPL8/PTPN2/GRB10/MZB1/AGT/PRKCQ/LPL/OGT/PRKAA1/CISH/ATP2B1/SORBS1	18
BP	GO:0042133	neurotransmitter metabolic process	32/2619	153/18670	0.01238	0.06795	0.05096	GCH1/GCHFR/JAK2/ALDH7A1/SDS/CLU/SMAD3/DDAH1/RORA/COMT/CX3CR1/NQO1/INSR/NAALAD2/DPYS/GCAT/MOXD1/DDAH2/IFNG/HDC/AGT/ASS1/TSPO/NOS3/ALDH9A1/CPS1/P2RX4/HBB/ATP2B4/HNMT/PTK2B/TH	32
BP	GO:0050718	positive regulation of interleukin-1 beta secretion	10/2619	33/18670	0.01241	0.06802	0.05102	AIM2/RIPK2/LILRA2/NLRP1/CARD8/HMGB1/NOD2/LPL/GSDMD/TLR8	10
BP	GO:0061448	connective tissue development	52/2619	273/18670	0.01249	0.06842	0.05132	PITX1/HOXA11/EFEMP1/NOTCH1/SCARA3/WNT5B/SOX9/MAPK3/MGP/SMAD3/CFLAR/FTO/PTH1R/LTBP3/STC1/RUNX3/CDK4/BMP4/GDF5/WNT11/TNMD/BBS4/CD44/OSR2/ID4/OXCT1/ACAT1/LRP5/COMP/FGF18/SIX2/MMP13/EGR1/PDGFB/ZNF219/SCIN/UBB/COL6A3/HIF1A/MBL2/HOXA5/IL6R/MAF/TYMS/ID2/TIMP1/ATF2/XBP1/GPR4/HMGA2/SATB2/PIK3CA	52
BP	GO:0035065	regulation of histone acetylation	14/2619	53/18670	0.01255	0.0685	0.05138	MAPK3/SNCA/CHEK1/NAP1L2/SET/SETD5/ZNF451/EID1/ARRB1/AUTS2/TAF7/RUVBL2/PIWIL2/TWIST1	14
BP	GO:0045744	negative regulation of G protein-coupled receptor signaling pathway	14/2619	53/18670	0.01255	0.0685	0.05138	CCL5/RPH3AL/SNCA/ADA/HTR2B/KLK14/ARRB1/ADRB2/RGS4/GPRASP1/ATP2B4/RGS13/CRY1/CXCL8	14
BP	GO:0060563	neuroepithelial cell differentiation	14/2619	53/18670	0.01255	0.0685	0.05138	NOTCH1/CDH2/TMEM231/SERPINE1/WNT11/LEF1/B9D1/MCOLN3/INSM1/RBPJ/SOD1/JAG2/SLC4A7/CEBPB	14
BP	GO:1903901	negative regulation of viral life cycle	20/2619	85/18670	0.01255	0.0685	0.05138	SRPK1/CCL5/FAM111A/SLPI/TNIP1/APOBEC3C/TRIM26/ZC3HAV1/ISG20/CCL8/BANF1/TRIM21/PML/IFITM2/CCNK/IFI16/FCN1/TRIM32/VAPA/HMGA2	20
BP	GO:0006638	neutral lipid metabolic process	28/2619	130/18670	0.01257	0.0685	0.05138	PNPLA4/SIK1/LIPC/FBXW7/SNCA/SLC22A4/ABHD6/AGPAT5/APOE/DGKA/SLC27A5/GK/GPX1/CAT/APOC1/DGKZ/NR1H2/ANG/CPS1/PCK2/PLCE1/LPL/FABP7/FABP3/ABHD2/LPIN1/SEL1L/LMF1	28
BP	GO:0042157	lipoprotein metabolic process	28/2619	130/18670	0.01257	0.0685	0.05138	PIGT/GPAA1/ZDHHC18/APOLD1/PEMT/APOL3/PIGK/APOM/APOL1/PGAP2/ATM/ZDHHC4/APOL6/ZDHHC17/APOE/PIGA/PIGP/DPM3/UGCG/APOC1/APOL2/ZDHHC3/PIGH/PPM1B/PIGZ/PIGC/ATG12/PGAP3	28
BP	GO:0043200	response to amino acid	25/2619	113/18670	0.01272	0.0692	0.0519	SIX1/PTN/PEMT/DNMT1/UBR2/BAD/EGFR/BAIAP2/NTRK2/SOCS1/RRAGA/ASS1/CHUK/CPS1/LAMTOR2/CREB1/RRAGD/COL4A1/XBP1/COL3A1/SESN1/HNRNPD/CEBPB/BCL11A/ASNS	25
BP	GO:0060964	regulation of gene silencing by miRNA	25/2619	113/18670	0.01272	0.0692	0.0519	POLR2J/POLR2I/NUP160/POLR2L/NUP153/EGFR/POLR2E/POLR2F/PUM2/TPR/BMP4/NUP50/PPARG/POLR2C/SEC13/RANBP2/POLR2G/NUP210/DND1/PPP3CA/NCOR1/NUP43/NDC1/NUP98/NUP62	25
BP	GO:0001774	microglial cell activation	13/2619	48/18670	0.01281	0.06924	0.05193	SPHK1/TREM2/JAK2/SNCA/CLU/PTPRC/ATM/IFNG/IL6/NAMPT/TYROBP/CST7/TLR8	13
BP	GO:0002269	leukocyte activation involved in inflammatory response	13/2619	48/18670	0.01281	0.06924	0.05193	SPHK1/TREM2/JAK2/SNCA/CLU/PTPRC/ATM/IFNG/IL6/NAMPT/TYROBP/CST7/TLR8	13
BP	GO:0002711	positive regulation of T cell mediated immunity	13/2619	48/18670	0.01281	0.06924	0.05193	HLA-C/MALT1/HLA-F/HLA-G/HLA-A/PTPRC/HLA-B/HLA-E/CD81/IL6/XCL1/TNFSF4/FBXO38	13
BP	GO:0044764	multi-organism cellular process	13/2619	48/18670	0.01281	0.06924	0.05193	RNF125/BIRC3/FCHSD2/PUM2/BIRC2/CCR5/TSPAN6/IRF3/CXCR4/GPATCH3/DDX60/SEC14L1/RIOK3	13
BP	GO:0061647	histone H3-K9 modification	13/2619	48/18670	0.01281	0.06924	0.05193	JARID2/DNMT1/CHEK1/ARID4B/NAP1L2/SETD5/ZNF451/KDM3A/ATRX/ARID4A/SUV39H2/KAT2B/PIWIL2	13
BP	GO:1903727	positive regulation of phospholipid metabolic process	13/2619	48/18670	0.01281	0.06924	0.05193	KIT/HTR2B/FGR/TAZ/CD81/DGKZ/PDGFB/CD19/CCR7/NOD2/FABP3/PTK2B/STOML2	13
BP	GO:1900077	negative regulation of cellular response to insulin stimulus	11/2619	38/18670	0.01282	0.06924	0.05193	PTPRE/ENPP1/PRKCB/PID1/SOCS1/PTPN2/GRB10/PRKCQ/LPL/PRKAA1/CISH	11
BP	GO:1904037	positive regulation of epithelial cell apoptotic process	11/2619	38/18670	0.01282	0.06924	0.05193	JAK2/HLA-G/BAD/CD40/GPER1/TIA1/PRKCI/IL6/AKR1C3/SORT1/CD40LG	11
BP	GO:0009163	nucleoside biosynthetic process	12/2619	43/18670	0.01292	0.06949	0.05212	NME4/TK2/NME7/IMPDH2/NME5/ADK/ADA/NME3/TYMP/GUK1/CTPS1/NT5E	12
BP	GO:0010863	positive regulation of phospholipase C activity	12/2619	43/18670	0.01292	0.06949	0.05212	ITK/EGFR/NTRK2/NTF3/KIT/HTR2B/SELE/AGT/ANG/TXK/LPAR2/BDNF	12
BP	GO:0042088	T-helper 1 type immune response	12/2619	43/18670	0.01292	0.06949	0.05212	IL27RA/RIPK2/SEMA4A/IL4R/LEF1/RELB/XCL1/SLC11A1/TNFSF4/HMGB1/IL6R/CCR2	12
BP	GO:0045429	positive regulation of nitric oxide biosynthetic process	12/2619	43/18670	0.01292	0.06949	0.05212	JAK2/CLU/SMAD3/DDAH1/INSR/DDAH2/IFNG/AGT/ASS1/P2RX4/HBB/PTK2B	12
BP	GO:0045687	positive regulation of glial cell differentiation	12/2619	43/18670	0.01292	0.06949	0.05212	PTN/NOTCH1/TNFRSF1B/ZNF365/PRMT5/BIN1/PPARG/CXCR4/HDAC1/OLIG2/ID2/TENM4	12
BP	GO:0009896	positive regulation of catabolic process	76/2619	423/18670	0.01293	0.06949	0.05212	TNFAIP3/NUPR1/CEBPA/TREM2/TNFRSF1B/SOX9/FBXW7/MAPK3/RIPK2/VPS13C/TBK1/SNCA/CLU/HERPUD1/TRIM22/NDUFA13/CBFA2T3/FTO/AREL1/ATM/BARD1/BAD/EGF/UVRAG/PINK1/APOE/GSK3B/INSR/CHFR/IDE/SEC22B/ZC3HAV1/PSMC2/PIM2/ROCK1/PFKFB3/ADRB2/CD81/IFNG/PRR5L/PLK2/TRIB1/TRIM21/PIK3CB/IGF1/DET1/KDR/TMEM59/IL6/POLR2G/CSNK1A1/MTDH/RNF19B/HMGB1/C4BPB/DTL/CSNK1E/EDEM1/OPTN/KAT5/ZFP36L2/PSMD10/HIF1A/TPCN1/PRKAA1/NOD1/IKBKG/RNF14/TRIM32/SESN1/PTK2B/HNRNPD/CLEC16A/OAZ3/TWIST1/NEDD4L	76
BP	GO:0038061	NIK/NF-kappaB signaling	37/2619	183/18670	0.01303	0.0699	0.05243	NFKBIA/SPHK1/TREM2/BIRC3/AKIP1/SKP1/TRIP6/MALT1/PSMB9/REL/EGFR/BIRC2/COPS8/TSPAN6/NOL3/PTPN22/PSMC2/RC3H2/CD27/RELB/PSMB6/CARD14/CHUK/PSMC3/NR3C2/PSMD8/HMGB1/NOD2/PSMB5/PPM1B/PSMD10/LIME1/AGO3/CYLD/NOD1/TNFSF14/EP300	37
BP	GO:0061136	regulation of proteasomal protein catabolic process	37/2619	183/18670	0.01303	0.0699	0.05243	NUPR1/CEBPA/TREM2/FBXW7/CLU/LAMP3/HERPUD1/GABARAPL2/CBFA2T3/UBE2J1/PINK1/APOE/GSK3B/CHFR/HFE/PSMC2/GPX1/FHIT/PLK2/TRIB1/DET1/CSNK1A1/RNF19B/UBB/UBQLN4/GLMN/CSNK1E/EDEM1/NFE2L1/PSMD10/TMF1/OGT/RYBP/RNF14/N4BP1/CLEC16A/USP14	37
BP	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	23/2619	102/18670	0.01312	0.0702	0.05265	TREM2/LGMN/HLA-DRB4/SEC24A/KIF2A/AP1B1/RACGAP1/DCTN6/DCTN3/CTSF/AP2M1/CAPZA1/SEC13/DCTN2/CENPE/KIF11/DYNC1I1/KIF4A/KIF15/HLA-DOB/AP1S1/HLA-DQB1/DYNC1H1	23
BP	GO:0098869	cellular oxidant detoxification	23/2619	102/18670	0.01312	0.0702	0.05265	GCH1/LTC4S/PTGS1/FBLN5/ALOX5AP/APOM/NQO1/APOE/GPX3/PRDX6/MGST3/GSTZ1/PXDN/GPX1/CAT/GPX4/NOS3/IPCEF1/SOD1/HBB/PRDX2/SESN1/TXNRD2	23
BP	GO:0060828	regulation of canonical Wnt signaling pathway	54/2619	286/18670	0.01312	0.0702	0.05265	SFRP1/NOTCH1/FOLR1/WNT5B/GPC5/CDH2/SOX9/IGFBP2/CHD8/SMAD3/ASPM/TNKS2/PSMB9/NLE1/EGFR/EGF/ZBED2/APOE/GSK3B/IGFBP4/WNT11/PLEKHA4/PSMC2/USP47/USP34/NFKB1/PSMB6/WLS/PSMC3/EGR1/RBPJ/CSNK1A1/DKK4/PIN1/USP8/PSMD8/LGR5/FERMT1/PSMB5/FRAT1/CSNK1E/RUVBL2/PFDN5/PSMD10/TLE3/HDAC1/CYLD/TCF7L2/TLE2/FZD6/CAPRIN2/UBR5/FZD7/DDIT3	54
BP	GO:0001952	regulation of cell-matrix adhesion	26/2619	119/18670	0.01317	0.0704	0.0528	SFRP1/MACF1/SMAD3/SERPINE1/GSK3B/LIMCH1/EFNA5/ROCK1/POSTN/CD3E/PIK3CB/KDR/MAP4K4/CLASP1/MYOC/MMP12/VEGFA/CCR7/FERMT1/SEMA3E/NINJ1/EMP2/NF2/CIB1/PTK2B/HOXA7	26
BP	GO:0050687	negative regulation of defense response to virus	8/2619	24/18670	0.01349	0.07205	0.05404	RNF125/MICB/HTRA1/TSPAN6/GPATCH3/PPM1B/SEC14L1/RIOK3	8
BP	GO:0032768	regulation of monooxygenase activity	16/2619	64/18670	0.01365	0.07284	0.05463	GCH1/SNCA/DDAH1/EGFR/APOE/HTR2B/NFKB1/DDAH2/IFNG/NOS3/S100A1/HIF1A/ATP2B4/NOD1/KRAS/PTK2B	16
BP	GO:1903829	positive regulation of cellular protein localization	60/2619	324/18670	0.0139	0.07405	0.05554	ZIC1/PTN/TREM2/ECT2/FIS1/FBXW7/NIPBL/SMAD3/MICALL2/SYT11/BAD/EGFR/EGF/PRNP/PINK1/PRKCH/GSK3B/TPR/ERBB2/TMEM30A/GZMB/PPP1R13B/ANK3/NMD3/GPER1/NDC80/CD81/YWHAH/IFNG/PRR5L/PCM1/PRKCI/TP53BP2/RAC2/SEC16A/CD247/TYROBP/ATG13/EDEM1/VAMP2/CAMK1/PRKAA1/CYLD/TARDBP/RANGRF/CIB1/NGFR/GTSE1/CDK1/TCF7L2/LGALS3/CEP290/ERBB4/UBL5/FLNA/UBR5/SMO/LRIG2/NUP62/SORBS1	60
BP	GO:0097696	STAT cascade	34/2619	166/18670	0.0139	0.07405	0.05554	AKR1B1/NOTCH1/STAT1/SOCS6/JAK2/CCL5/CRLF1/IL15/IL7R/PTPRC/NMI/EGF/SOCS1/PECAM1/KIT/CTF1/CD40/PTPN2/F2R/STAT4/IFNG/AGT/IGF1/CRLF3/IL6/ARL2BP/NF2/IL6R/STAT5A/GGNBP2/GHR/ERBB4/SH2B3/CCR2	34
BP	GO:0046578	regulation of Ras protein signal transduction	46/2619	238/18670	0.01398	0.07446	0.05584	NOTCH1/JAK2/ECT2/RASGRP1/SH2B2/STK19/ARHGEF3/SOS1/ARHGEF40/ITSN2/ARHGEF9/CDC42SE1/TIMP2/APOE/DENND4B/MADD/ARHGEF2/SHOC2/ARRB1/F2R/NTRK1/AUTS2/FOXM1/ARHGEF7/IGF1/RASIP1/MAP4K4/MYOC/ARHGAP35/PLCE1/NET1/OGT/RAF1/TNK1/AKAP13/EPS8L2/RALGPS2/MAPRE2/COL3A1/KRAS/GPR4/ARFGEF1/KANK2/MCF2L/NUP62/EPOR	46
BP	GO:1903201	regulation of oxidative stress-induced cell death	18/2619	75/18670	0.01416	0.07502	0.05627	FBXW7/SLC7A11/HGF/NME5/PINK1/MAPK7/NOL3/GPX1/HSPB1/TRAP1/SFPQ/MCL1/SOD1/HIF1A/VNN1/PYCR1/ATF4/PSAP	18
BP	GO:0043409	negative regulation of MAPK cascade	37/2619	184/18670	0.01417	0.07502	0.05627	GBP1/DUSP5/SFRP1/IRAK3/BTN2A2/DUSP6/TNIP1/UCHL1/PTPRC/PINK1/APOE/ATF3/LAX1/BMP4/DNAJA1/PTPN22/PHB/GPER1/PTPN2/ARRB1/FOXM1/NDRG2/LMO3/RGS4/SIRT3/MYC/DUSP2/EIF3A/PIN1/NCOR1/PSMD10/CYLD/NF2/TAOK3/FBLN1/SH2B3/NUP62	37
BP	GO:0030218	erythrocyte differentiation	25/2619	114/18670	0.01418	0.07502	0.05627	P4HTM/STAT1/JAK2/ADAR/KIT/BMP4/EPB42/MED1/JMJD6/PTPN2/PTBP3/MFHAS1/DNASE2/ZNF16/VEGFA/ARID4A/NFE2L1/HIF1A/HOXA5/ERCC2/CEBPG/ID2/SFXN1/SH2B3/TRIM58	25
BP	GO:0045446	endothelial cell differentiation	25/2619	114/18670	0.01418	0.07502	0.05627	PTN/NOTCH1/APOLD1/TMEM100/NOTCH4/STC1/RAP2C/PECAM1/BMP4/TNMD/ROCK1/GPX1/PPP1R16B/CXCR4/LAMA5/S1PR1/CDH5/KDR/RBPJ/GSTM3/VEGFA/HOXB5/TJP2/FOXJ2/RAP1B	25
BP	GO:0071248	cellular response to metal ion	38/2619	190/18670	0.01421	0.07502	0.05627	CEBPA/LGMN/ECT2/MAPK3/SNCA/ALOX5AP/SYT11/EGFR/PRNP/NQO1/HFE/KCNK3/ANK3/GUCA1A/SYT17/DAXX/CRHBP/CHUK/TSPO/CCNB1/AKR1C3/ADCY1/P2RX4/NFE2L1/SOD1/AQP2/MCOLN1/PRKAA1/CREB1/ID2/SYT1/RASGRP2/ATF4/SERPINF1/HSPA5/CPNE6/TH/NCF1	38
BP	GO:0046425	regulation of JAK-STAT cascade	29/2619	137/18670	0.01421	0.07502	0.05627	AKR1B1/NOTCH1/JAK2/CCL5/CRLF1/IL15/PTPRC/EGF/SOCS1/PECAM1/KIT/CTF1/CD40/PTPN2/F2R/IFNG/AGT/IGF1/CRLF3/IL6/ARL2BP/NLK/NF2/IL6R/GGNBP2/GHR/ERBB4/SH2B3/PTK2B	29
BP	GO:0001763	morphogenesis of a branching structure	39/2619	196/18670	0.01424	0.07502	0.05627	SIX1/HOXA11/SFRP1/NOTCH1/AR/SOX9/PGF/HGF/SEMA3A/EGF/CTNNBIP1/NOTCH4/RXRA/BMP4/LEF1/MED1/LAMA5/FOXF1/RBM15/AGT/LRP5/SIX2/MYC/RASIP1/PML/PRDM1/VEGFA/PLXND1/MAGED1/SEMA3E/HOXA5/TIMELESS/SETD2/PLXNA1/COL4A1/FKBPL/KRAS/SMO/BCL11A	39
BP	GO:0007260	tyrosine phosphorylation of STAT protein	20/2619	86/18670	0.01426	0.07502	0.05627	JAK2/CCL5/CRLF1/IL15/SOCS1/PECAM1/KIT/CTF1/CD40/PTPN2/IFNG/IGF1/IL6/ARL2BP/NF2/IL6R/GGNBP2/GHR/ERBB4/SH2B3	20
BP	GO:0042130	negative regulation of T cell proliferation	15/2619	59/18670	0.01426	0.07502	0.05627	BTN2A2/HLA-G/PLA2G2D/LILRB2/TNFRSF21/CTLA4/IDO1/PRNP/TNFRSF14/BMP4/ERBB2/PELI1/XCL1/GLMN/CEBPB	15
BP	GO:0045071	negative regulation of viral genome replication	15/2619	59/18670	0.01426	0.07502	0.05627	SRPK1/CCL5/FAM111A/SLPI/TNIP1/APOBEC3C/ZC3HAV1/ISG20/CCL8/BANF1/IFITM2/CCNK/IFI16/VAPA/HMGA2	15
BP	GO:1902883	negative regulation of response to oxidative stress	15/2619	59/18670	0.01426	0.07502	0.05627	SLC7A11/HGF/NME5/MCTP1/PINK1/MAPK7/NOL3/GPX1/HSPB1/TRAP1/HIF1A/VNN1/PYCR1/ATF4/PSAP	15
BP	GO:2000351	regulation of endothelial cell apoptotic process	15/2619	59/18670	0.01426	0.07502	0.05627	TNFAIP3/NDNF/ANGPT1/HLA-G/TNIP2/SERPINE1/MAPK7/CD40/GPER1/KRIT1/PRKCI/KDR/AKR1C3/SCG2/CD40LG	15
BP	GO:2000756	regulation of peptidyl-lysine acetylation	15/2619	59/18670	0.01426	0.07502	0.05627	MAPK3/SNCA/CHEK1/NAP1L2/SET/SETD5/ZNF451/EID1/ARRB1/AUTS2/TAF7/RUVBL2/PRKAA1/PIWIL2/TWIST1	15
BP	GO:0046879	hormone secretion	58/2619	312/18670	0.01426	0.07502	0.05627	SFRP1/JAK2/CCL5/RPH3AL/TACR2/SRI/SLC25A4/MPC2/CD38/ARL2/RBP4/BAD/EGFR/HFE/EFNA5/RAB11FIP1/GPER1/TCIRG1/ARRB1/HADH/OXCT1/IFNG/ITPR2/CHRNA3/SIRT3/AGT/PTPRN2/CRHBP/LRP5/VAMP7/MAP4K4/IL6/GHSR/ARL2BP/ABCC8/CPE/ANO1/PPP3CA/SSTR5/LTBP4/HIF1A/TMF1/NMB/IL1RN/TARDBP/TAC1/GDF9/CACNA1D/RAF1/CREB1/GAL/RAB11B/TCF7L2/CCKAR/ENSA/CRY1/INHBB/PASK	58
BP	GO:0043270	positive regulation of ion transport	52/2619	275/18670	0.0143	0.07519	0.0564	CXCL9/CXCL10/SCN1B/ATP1B1/TREM2/FXYD1/CCL5/TACR2/PLCG2/SNCA/SRI/KCNQ1/CXCL11/FGF14/LILRA2/PINK1/STC1/TNFRSF11A/APOE/EHD3/KCNJ2/ANK3/GPER1/F2R/ADRB2/IFNG/AGT/TSPO/S100A1/HCRT/VAMP7/ATP8A1/PDGFB/XCL1/CD19/P2RX4/PLA2R1/CALCR/CACNB2/ABCB1/AKAP9/CACNA1D/TRPV2/GAL/LGALS3/HSPA2/FLNA/FABP3/CCR2/CEBPB/ATF4/ATP2B1	52
BP	GO:0051648	vesicle localization	57/2619	306/18670	0.01444	0.07584	0.05688	FOLR1/CDH2/MREG/RASGRP1/SEC24A/SNCA/NDE1/RIMS3/PREPL/PRKCB/SYT11/RAB27A/SERPINA1/SPG11/SYNJ1/PFN2/PINK1/GSK3B/PPP6R3/PCDH17/BLOC1S1/SEC22B/TMEM230/MAGI2/TRAK1/BBS4/SEC13/F8/SYT17/DCTN2/TRAPPC2L/KIF5C/CNIH1/TRAPPC10/LRMP/DYNC1I1/SEC16A/VAMP7/CLASP1/ADCY1/DYNC1H1/AP1AR/TMED2/VAMP2/CACNB2/WDR11/TMED9/TMED10/CACNA1D/IKBKG/RAB11B/ANKRD28/SYT1/SYN1/RAP1B/NAPA/CD59	57
BP	GO:0003014	renal system process	26/2619	120/18670	0.01463	0.07677	0.05758	AKR1B1/LGMN/MAGED2/PRKAR2A/KCNQ1/BTC/HSD11B2/COMT/STC1/CORO2B/BMP4/KLHL3/F2R/CHRNA3/AGT/AKR1C3/ADCY1/PDGFB/HBB/EMP2/AQP2/HAS2/TAC1/ADCY2/PSAP/CORIN	26
BP	GO:0002706	regulation of lymphocyte mediated immunity	31/2619	149/18670	0.0147	0.077	0.05776	HLA-C/PARP3/TNFRSF1B/RASGRP1/TFRC/IL27RA/MALT1/HLA-F/HLA-G/MICB/IL7R/HLA-A/PTPRC/THOC1/HLA-B/HLA-E/HFE/CD96/CD28/CRTAM/CD40/CD81/CR1/IL6/XCL1/TNFSF4/HMGB1/C4BPB/ULBP2/CCR2/FBXO38	31
BP	GO:0006294	nucleotide-excision repair, preincision complex assembly	9/2619	29/18670	0.01476	0.077	0.05776	CETN2/RPA1/RPA3/CCNH/UBB/DDB2/ERCC2/MNAT1/GTF2H3	9
BP	GO:0007263	nitric oxide mediated signal transduction	9/2619	29/18670	0.01476	0.077	0.05776	NDNF/DDAH1/EGFR/APOE/DDAH2/AGT/NOS3/VEGFA/ATP2B4	9
BP	GO:0015949	nucleobase-containing small molecule interconversion	9/2619	29/18670	0.01476	0.077	0.05776	NME4/RRM2/NME3/AK1/AK6/GUK1/DCTD/CTPS1/TYMS	9
BP	GO:0031063	regulation of histone deacetylation	9/2619	29/18670	0.01476	0.077	0.05776	KDM5A/PRKD2/NIPBL/TADA3/PINK1/ING2/ZNHIT1/VEGFA/AKAP8	9
BP	GO:0033032	regulation of myeloid cell apoptotic process	9/2619	29/18670	0.01476	0.077	0.05776	CCL5/SLC7A11/ADAM17/CCR5/PIK3CB/GHSR/NOD2/CXCR2/PIK3CD	9
BP	GO:0044068	modulation by symbiont of host cellular process	9/2619	29/18670	0.01476	0.077	0.05776	TNIP1/BAD/KPNA2/CCL8/KPNB1/CCNK/KPNA1/KPNA3/VAPA	9
BP	GO:0002720	positive regulation of cytokine production involved in immune response	14/2619	54/18670	0.01481	0.07701	0.05776	MAPK3/MALT1/HLA-F/HLA-G/TNFRSF14/HLA-E/CD81/IL6/XCL1/TNFSF4/NOD2/DDX1/DDX21/BCL10	14
BP	GO:0009066	aspartate family amino acid metabolic process	14/2619	54/18670	0.01481	0.07701	0.05776	ALDH7A1/BHMT2/SDS/THNSL2/GOT1/DDO/SMS/GCAT/ASRGL1/MSRA/ASS1/DLD/AHCY/ASNS	14
BP	GO:0090329	regulation of DNA-dependent DNA replication	14/2619	54/18670	0.01481	0.07701	0.05776	CDC7/FBXW7/NBN/CHEK2/ZNF365/DBF4/DONSON/BRCA2/ATRX/SMC1A/TIMELESS/STOML2/RFC2/FBXO5	14
BP	GO:1904645	response to amyloid-beta	14/2619	54/18670	0.01481	0.07701	0.05776	TREM2/LGMN/PRNP/GSK3B/CASP4/ADRB2/IGF1/MMP13/NAMPT/EPHA4/MMP12/CALCR/BCL2L2/NGFR	14
BP	GO:0006901	vesicle coating	17/2619	70/18670	0.01498	0.07787	0.0584	FOLR1/SEC24A/SERPINA1/PPP6R3/SEC22B/SEC13/F8/TRAPPC2L/CNIH1/TRAPPC10/SEC16A/TMED2/TMED9/TMED10/ANKRD28/NAPA/CD59	17
BP	GO:0035967	cellular response to topologically incorrect protein	33/2619	161/18670	0.01504	0.07808	0.05857	SDF2/ATP6V0D1/KLHDC3/HERPUD1/KDELR3/NCK2/YIF1A/ATF3/DNAJB14/CREB3/DDX11/TATDN2/PTPN2/EXTL2/DAXX/MBTPS1/ATF6/ANKZF1/TBL2/HSPA6/EDEM1/OPTN/DNAJC3/CXXC1/EP300/XBP1/HSPA2/CXCL8/ATF4/HSPA5/ASNS/STC2/DDIT3	33
BP	GO:0032757	positive regulation of interleukin-8 production	13/2619	49/18670	0.01526	0.07916	0.05937	PRKD2/SERPINE1/ELANE/F2R/TLR5/NOD2/CD58/CD2/FCN1/BCL10/MYD88/TLR8/DDIT3	13
BP	GO:0042594	response to starvation	38/2619	191/18670	0.01541	0.07964	0.05974	SFRP1/SIK1/MAP3K5/DAP/MAPK3/GABARAPL1/FAS/GABARAPL2/SLC38A2/COMT/ATF3/RRAGA/HFE/HMGCL/PIK3C2B/PPARG/OXCT1/ACAT1/TBL2/HCRT/AKR1C3/CPS1/PCK2/HNRNPA1/WRN/PRKAA1/IFI16/RRAGD/CDKN1A/XBP1/SESN1/INHBB/ATF4/HSPA5/GABARAP/ASNS/CLEC16A/DDIT3	38
BP	GO:0000737	DNA catabolic process, endonucleolytic	10/2619	34/18670	0.01542	0.07964	0.05974	DNASE1L3/DNASE1L1/SETMAR/APAF1/IL6/DNASE2/HMGB1/KPNB1/DFFB/KPNA1	10
BP	GO:0006099	tricarboxylic acid cycle	10/2619	34/18670	0.01542	0.07964	0.05974	SDHC/ME2/IREB2/MDH2/SDHD/DLD/PDHB/SUCLG1/MDH1/FH	10
BP	GO:0070884	regulation of calcineurin-NFAT signaling cascade	10/2619	34/18670	0.01542	0.07964	0.05974	CAMTA1/PRNP/GSK3B/MAPK7/DYRK2/IGF1/HOMER3/ATP2B4/CIB1/FHL2	10
BP	GO:0106056	regulation of calcineurin-mediated signaling	10/2619	34/18670	0.01542	0.07964	0.05974	CAMTA1/PRNP/GSK3B/MAPK7/DYRK2/IGF1/HOMER3/ATP2B4/CIB1/FHL2	10
BP	GO:0007548	sex differentiation	51/2619	270/18670	0.01544	0.07964	0.05974	HOXA11/SFRP1/NUPR1/AR/HOXA10/KDM5A/SOX9/ERCC1/NIPBL/ASPM/FOXC1/TCF7/SDC1/SEMA3A/ARID4B/ATM/RBP4/MERTK/INSR/KIT/ING2/PLEKHA1/ARRB1/NTRK1/ZFPM2/NOS3/RAB13/NASP/ANG/BRCA2/AKR1C3/AXL/EREG/ATRX/VEGFA/UBB/DHCR24/IRX5/ARID4A/SOD1/TMF1/MEA1/BCL2L2/GDF9/TYRO3/PATZ1/SGPL1/INHBB/FLNA/CEBPB/HSPA5	51
BP	GO:0007095	mitotic G2 DNA damage checkpoint	7/2619	20/18670	0.01545	0.07964	0.05974	NBN/ATM/DONSON/TAOK1/TAOK3/CDK1/HMGA2	7
BP	GO:0039529	RIG-I signaling pathway	7/2619	20/18670	0.01545	0.07964	0.05974	RNF125/BIRC3/PUM2/BIRC2/GPATCH3/DDX60/SEC14L1	7
BP	GO:0006195	purine nucleotide catabolic process	12/2619	44/18670	0.01556	0.08004	0.06003	PDE1A/NT5C2/ADA/SAMHD1/NUDT9/GPX1/PNP/NUDT11/ACAT1/DNPH1/NT5E/AMPD3	12
BP	GO:1904407	positive regulation of nitric oxide metabolic process	12/2619	44/18670	0.01556	0.08004	0.06003	JAK2/CLU/SMAD3/DDAH1/INSR/DDAH2/IFNG/AGT/ASS1/P2RX4/HBB/PTK2B	12
BP	GO:0010769	regulation of cell morphogenesis involved in differentiation	56/2619	301/18670	0.01557	0.08004	0.06003	GBP1/CDH2/UST/SEMA4D/MYCBP2/MACF1/TNIK/SEMA4A/SS18L1/SEMA3A/FGF13/TUBB2B/BAIAP2/CHN1/NTRK2/NEDD9/APOE/GSK3B/SEMA4C/EFNA5/TRAK1/PARP6/SIPA1L1/YWHAH/POSTN/ARHGEF7/CHRNA3/SEMA3F/VAMP7/RND2/TLX2/MYOC/EPHA4/VEGFA/PLXND1/ARHGAP35/AP1AR/SEMA3E/PPP3CA/HAS2/CTTN/CIB1/GOLGA4/NGFR/TRPV2/CDKL5/PLXNA1/FBLN1/CYFIP1/CAPRIN2/FLNA/DSCAM/CAMK2B/ACTR2/BDNF/NEDD4L	56
BP	GO:0043001	Golgi to plasma membrane protein transport	11/2619	39/18670	0.01565	0.08024	0.06018	MACF1/PREPL/ANK3/BBS1/VAMP3/SEC16A/VAMP7/OPTN/VAMP2/GOLGA4/GOLPH3	11
BP	GO:0072350	tricarboxylic acid metabolic process	11/2619	39/18670	0.01565	0.08024	0.06018	SDHC/ME2/IREB2/MDH2/SDHD/ASS1/DLD/PDHB/SUCLG1/MDH1/FH	11
BP	GO:0072595	maintenance of protein localization in organelle	11/2619	39/18670	0.01565	0.08024	0.06018	GPAA1/SKP1/KDELR3/ARL2/BARD1/PINK1/BBS4/TSPO/PML/ARL2BP/HSPA5	11
BP	GO:0046660	female sex differentiation	25/2619	115/18670	0.01578	0.08075	0.06056	SFRP1/NUPR1/FOXC1/ATM/RBP4/MERTK/INSR/KIT/PLEKHA1/ARRB1/ZFPM2/NOS3/ANG/BRCA2/AXL/EREG/VEGFA/UBB/SOD1/GDF9/TYRO3/SGPL1/INHBB/CEBPB/HSPA5	25
BP	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	22/2619	98/18670	0.0158	0.08075	0.06056	LGMN/HLA-DRB4/SEC24A/KIF2A/AP1B1/RACGAP1/DCTN6/DCTN3/CTSF/AP2M1/CAPZA1/SEC13/DCTN2/CENPE/KIF11/DYNC1I1/KIF4A/KIF15/HLA-DOB/AP1S1/HLA-DQB1/DYNC1H1	22
BP	GO:0060191	regulation of lipase activity	22/2619	98/18670	0.0158	0.08075	0.06056	CCL5/LIPC/SNCA/ITK/EGFR/NTRK2/NTF3/KIT/ARL1/HTR2B/SELE/APOC1/AGT/NR1H2/ANG/TXK/SORT1/PLA2R1/LPL/LPAR2/BDNF/LMF1	22
BP	GO:0072577	endothelial cell apoptotic process	16/2619	65/18670	0.01581	0.08075	0.06056	TNFAIP3/NDNF/MAP3K5/ANGPT1/HLA-G/TNIP2/SERPINE1/MAPK7/CD40/GPER1/KRIT1/PRKCI/KDR/AKR1C3/SCG2/CD40LG	16
BP	GO:0072678	T cell migration	16/2619	65/18670	0.01581	0.08075	0.06056	CXCL10/CD200/CCL5/IL27RA/CXCL13/CXCL11/GPR183/ADAM17/TNFRSF14/ITGB7/S1PR1/ZAP70/XCL1/PIK3CD/TNFSF14/CCR2	16
BP	GO:0060041	retina development in camera-type eye	30/2619	144/18670	0.0159	0.08107	0.0608	PTN/DIO3/SOX9/LAMC3/MDM1/RBP4/IMPDH2/SMARCD3/MERTK/NTRK2/MED1/GPM6A/JMJD6/TCIRG1/ROM1/LRP5/TGIF2/IFT140/RS1/IRX5/PRPH2/PFDN5/HIF1A/ATP2B4/SIX3/COL4A1/DSCAM/SERPINF1/MYH10/ATP2B1	30
BP	GO:1904064	positive regulation of cation transmembrane transport	30/2619	144/18670	0.0159	0.08107	0.0608	CXCL9/CXCL10/ATP1B1/TREM2/FXYD1/PLCG2/SNCA/SRI/KCNQ1/CXCL11/FGF14/PINK1/EHD3/KCNJ2/ANK3/GPER1/F2R/ADRB2/IFNG/AGT/S100A1/XCL1/CD19/CALCR/CACNB2/AKAP9/GAL/HSPA2/FLNA/CCR2	30
BP	GO:0008360	regulation of cell shape	31/2619	150/18670	0.0161	0.082	0.0615	PTN/PLEKHO1/SEMA4D/SEMA4A/CDC42EP3/S100A13/BAIAP2/CDC42SE1/KIT/BRWD1/RHOF/EPB42/FGR/FERMT2/PHIP/KDR/RND2/VEGFA/PLXND1/ARHGAP35/SEMA3E/CCL13/PARVB/ANXA7/ATP10A/RHOH/PLXNA1/CCL7/CYFIP1/PTK2B/MYH10	31
BP	GO:0048754	branching morphogenesis of an epithelial tube	31/2619	150/18670	0.0161	0.082	0.0615	SIX1/HOXA11/NOTCH1/AR/SOX9/PGF/EGF/CTNNBIP1/NOTCH4/BMP4/LEF1/MED1/LAMA5/FOXF1/RBM15/AGT/LRP5/SIX2/MYC/RASIP1/PML/VEGFA/PLXND1/MAGED1/SEMA3E/HOXA5/TIMELESS/COL4A1/FKBPL/KRAS/SMO	31
BP	GO:0048477	oogenesis	20/2619	87/18670	0.01614	0.08211	0.06158	CDC25B/PTN/ERCC1/ASPM/ATM/DIAPH2/NPR2/IGF1/CCNB1/ANG/BRCA2/EREG/LGR5/YTHDC2/GDF9/PIWIL2/INHBB/PTK2B/DAZL/FBXO5	20
BP	GO:0030968	endoplasmic reticulum unfolded protein response	26/2619	121/18670	0.01621	0.08241	0.06181	ATP6V0D1/KLHDC3/HERPUD1/KDELR3/NCK2/YIF1A/ATF3/CREB3/DDX11/TATDN2/PTPN2/EXTL2/MBTPS1/ATF6/TBL2/EDEM1/DNAJC3/CXXC1/EP300/XBP1/CXCL8/ATF4/HSPA5/ASNS/STC2/DDIT3	26
BP	GO:0031346	positive regulation of cell projection organization	69/2619	383/18670	0.01622	0.08241	0.06181	PTN/SCN1B/SETX/NDNF/CEP135/STMN2/SEMA4D/MACF1/CFLAR/CDC42EP3/HGF/SS18L1/EZH2/TUBB2B/ITSN2/BAIAP2/NTRK2/APOE/RALA/KIT/EFNA5/TMEM30A/MAGI2/TRAK1/MNS1/BBS4/PARP6/CXCR4/GPM6A/SYT17/NTRK1/AUTS2/ARHGEF7/AGT/PRKCI/RAC2/VAMP7/RND2/EPHA4/VEGFA/PLXND1/ARHGAP35/CCR7/TENM3/CAMK1/KATNB1/GOLGA4/NGFR/TRPV2/CDKL5/PLXNA1/EPS8L2/SYT1/CYFIP1/EP300/CAPRIN2/PTK2B/STYXL1/DSCAM/FBXO38/C21orf91/SERPINF1/CAMK2B/ACTR2/HSPA5/CPNE6/BDNF/ARSB/NEDD4L	69
BP	GO:0071453	cellular response to oxygen levels	45/2619	234/18670	0.01625	0.08245	0.06184	SFRP1/PTN/NOTCH1/FAM162A/NDNF/CHCHD2/ATP6V0D1/DDAH1/FAS/CCNA2/RORA/CFLAR/PSMB9/BAD/PINK1/STC1/BACH1/NOL3/KCNK3/PSMC2/PPARG/PSMB6/CCNB1/PSMC3/MYC/TBL2/EGR1/RBPJ/PDK1/NAMPT/VEGFA/PSMD8/UBB/EGLN3/PSMB5/PSMD10/HIF1A/PRKAA1/SUV39H2/ACAA2/EP300/CUL2/ATF4/STC2/TWIST1	45
BP	GO:0000723	telomere maintenance	33/2619	162/18670	0.01641	0.08323	0.06243	SMC6/PARP3/DCLRE1C/MAPK3/ERCC1/HNRNPA2B1/NBN/POLD2/ATR/TNKS2/ATM/DNA2/ZNF365/NHP2/RPA1/RPA3/POLD4/SMC5/DCP2/MYC/BRCA2/PML/ATRX/HMBOX1/AURKB/HNRNPA1/RAD51C/PRKCQ/RAD50/NABP2/WRN/HNRNPD/RFC2	33
BP	GO:1901617	organic hydroxy compound biosynthetic process	51/2619	271/18670	0.0165	0.08361	0.06271	GCH1/AKR1B1/CYB5R1/SPHK1/QDPR/LBR/PLCG2/SNCA/CH25H/PMVK/OSBPL3/GOT1/ACOX2/ERLIN2/PCBD1/SLC7A11/PNPO/PTH1R/APOE/SLC27A5/CYP7B1/ASAH1/MOXD1/GPER1/SC5D/NFKB1/IFNG/MBTPS1/HDC/INSM1/SCP2/AKR1C3/PCK2/DHDDS/PLCE1/DHCR24/DHCR7/KPNB1/SOD1/DCT/PLCD1/PRKAA1/ISYNA1/CYB5R3/ACAA2/ACOT8/PTK2B/AKR1C4/NFYC/TH/MVK	51
BP	GO:0050806	positive regulation of synaptic transmission	34/2619	168/18670	0.01652	0.08364	0.06273	PTN/LGMN/TACR2/SNCA/RIMS3/LILRB2/EGFR/PRNP/BAIAP2/PINK1/CX3CR1/NTRK2/APOE/GSK3B/GPER1/ADRB2/NTRK1/PLK2/RGS4/ADCY1/TYROBP/EPHA4/CA2/VAMP2/CACNB2/NRGN/CALB2/TAC1/CACNA1D/CREB1/SYT1/PTK2B/CCR2/STAU1	34
BP	GO:0009612	response to mechanical stimulus	41/2619	210/18670	0.01659	0.08383	0.06288	NFKBIA/CXCL10/PTN/STAT1/IRF1/SOX9/IGFBP2/MAPK3/FAS/GOT1/CRADD/CHEK1/BAD/SLC38A2/EGFR/ANGPT2/KIT/GDF5/WNT11/PPARG/KCNJ2/CD40/PTGER4/CXCR4/NFKB1/NTRK1/POSTN/AGT/CCNB1/TLR5/PSPH/CASP8AP2/PKD2L1/RAF1/TNFSF14/BCL10/MYD88/COL3A1/PTK2B/TLR8/ASNS	41
BP	GO:0030178	negative regulation of Wnt signaling pathway	41/2619	210/18670	0.01659	0.08383	0.06288	WIF1/SFRP1/NOTCH1/WNT5B/CDH2/SOX9/IGFBP2/CHD8/CBY1/PSMB9/CTNNBIP1/APOE/GSK3B/MDFI/IGFBP4/WNT11/PSMC2/GRB10/PSMB6/PSMC3/EGR1/CSNK1A1/DKK4/PSMD8/CXXC4/TSKU/FERMT1/PSMB5/NLK/RUVBL2/PFDN5/PSMD10/TLE3/HDAC1/CYLD/SIX3/TCF7L2/TLE2/FZD6/DDIT3/HMGXB4	41
BP	GO:0051306	mitotic sister chromatid separation	15/2619	60/18670	0.01661	0.0839	0.06293	ATM/DLGAP5/PTTG1/TPR/BUB1B/LCMT1/NDC80/CENPE/CCNB1/CDC20/AURKB/TACC3/PTTG2/CENPF/FBXO5	15
BP	GO:1902903	regulation of supramolecular fiber organization	64/2619	352/18670	0.01663	0.08394	0.06296	SFRP1/IQGAP2/ACTR3B/STMN2/ARPC1A/SNCA/CLU/SMAD3/TMOD1/CDC42EP3/ARL2/FGF13/FCHSD2/PFN2/BAIAP2/NCK2/ACTR3/APOE/CORO2B/LIMCH1/CAPZA1/BIN1/MAPRE3/WNT11/ARHGEF2/ROCK1/GPX1/BBS4/PTGER4/CRYAB/S1PR1/DRG1/CDH5/RGS4/PPM1E/TAOK1/TMOD2/CLASP1/FHOD3/MAGEL2/MYOC/SCIN/ARHGAP35/CCR7/AP1AR/TMSB10/SPAST/KATNB1/ALMS1/ARPC5L/AKAP9/NF2/RANGRF/TAC1/CTTN/CIB1/AKAP13/HIP1R/CYFIP1/LIMA1/FLNA/PTK2B/ARFGEF1/ACTR2	64
BP	GO:0071466	cellular response to xenobiotic stimulus	36/2619	180/18670	0.01665	0.08396	0.06297	GSTA4/PTGS1/EPHX1/BPHL/CCNA2/RORA/EPHX2/AKR7A3/CFLAR/CHEK2/DDIT4/CES2/EGFR/NQO1/MGST3/GSTM4/AKR7A2/CES3/ASS1/CRHBP/GSTM5/EGR1/CRYZ/PDGFB/PCK2/SULT1A2/GSTM3/CASP9/USP8/FMO3/NAT2/CYB5R3/STAT5A/S100A12/GHR/SERPINF1	36
BP	GO:0042770	signal transduction in response to DNA damage	28/2619	133/18670	0.01692	0.08526	0.06395	NBN/ATR/CRADD/CHEK2/CHEK1/ATM/CD44/SMYD2/FOXM1/PLK2/CCNB1/BRCA2/PML/ATRX/CASP9/PLA2R1/DTL/BATF/KAT5/PSMD10/BABAM1/GTSE1/CDK1/CDKN1A/EP300/CEP63/TWIST1/RBL2	28
BP	GO:0006903	vesicle targeting	21/2619	93/18670	0.01697	0.08536	0.06403	FOLR1/SEC24A/SERPINA1/PPP6R3/SEC22B/SEC13/F8/TRAPPC2L/CNIH1/TRAPPC10/LRMP/SEC16A/CLASP1/AP1AR/TMED2/WDR11/TMED9/TMED10/ANKRD28/NAPA/CD59	21
BP	GO:0032092	positive regulation of protein binding	21/2619	93/18670	0.01697	0.08536	0.06403	RIPK2/APOE/GSK3B/HFE/BMP4/MAPRE3/SPON1/RFNG/NMD3/ARRB1/PLK2/EPHA4/PLXND1/PIN1/TCF7L2/HIP1R/LGALS3/EP300/CAPRIN2/MARK3/BDNF	21
BP	GO:0051650	establishment of vesicle localization	54/2619	290/18670	0.017	0.08545	0.06409	FOLR1/MREG/RASGRP1/SEC24A/SNCA/NDE1/RIMS3/PREPL/PRKCB/SYT11/RAB27A/SERPINA1/SPG11/SYNJ1/PFN2/PINK1/GSK3B/PPP6R3/BLOC1S1/SEC22B/TMEM230/TRAK1/BBS4/SEC13/F8/SYT17/DCTN2/TRAPPC2L/KIF5C/CNIH1/TRAPPC10/LRMP/DYNC1I1/SEC16A/VAMP7/CLASP1/ADCY1/DYNC1H1/AP1AR/TMED2/VAMP2/CACNB2/WDR11/TMED9/TMED10/CACNA1D/IKBKG/RAB11B/ANKRD28/SYT1/SYN1/RAP1B/NAPA/CD59	54
BP	GO:0042795	snRNA transcription by RNA polymerase II	17/2619	71/18670	0.0172	0.08575	0.06431	POLR2J/POLR2I/POLR2L/POLR2E/POLR2F/INTS6/POLR2C/INTS8/POU2F1/CCNT2/GTF2A2/POLR2G/NABP2/ELL2/CCNK/NCBP2/CDK9	17
BP	GO:0044786	cell cycle DNA replication	17/2619	71/18670	0.0172	0.08575	0.06431	CDC7/FBXW7/POLD2/CHEK2/DNA2/ORC3/RPA1/DBF4/RPA3/POLD4/DONSON/GINS1/BRCA2/ATRX/SMC1A/RFC2/FBXO5	17
BP	GO:1904427	positive regulation of calcium ion transmembrane transport	17/2619	71/18670	0.0172	0.08575	0.06431	CXCL9/CXCL10/ATP1B1/PLCG2/SNCA/SRI/CXCL11/FGF14/EHD3/GPER1/F2R/S100A1/XCL1/CD19/CALCR/CACNB2/HSPA2	17
BP	GO:0002070	epithelial cell maturation	6/2619	16/18670	0.01722	0.08575	0.06431	HIF1A/HOXA5/SIX3/TYMS/CDKN1A/XBP1	6
BP	GO:0006206	pyrimidine nucleobase metabolic process	6/2619	16/18670	0.01722	0.08575	0.06431	DPYS/TYMP/CPS1/CTPS1/TYMS/ALDH6A1	6
BP	GO:0010820	positive regulation of T cell chemotaxis	6/2619	16/18670	0.01722	0.08575	0.06431	CCL5/CXCL13/ADAM17/XCL1/TNFSF14/CCR2	6
BP	GO:0015074	DNA integration	6/2619	16/18670	0.01722	0.08575	0.06431	RLF/SETMAR/BANF1/ZNF93/NYNRIN/ZNF91	6
BP	GO:0033631	cell-cell adhesion mediated by integrin	6/2619	16/18670	0.01722	0.08575	0.06431	CCL5/CXCL13/ITGA5/ADA/CD3E/PODXL	6
BP	GO:0044827	modulation by host of viral genome replication	6/2619	16/18670	0.01722	0.08575	0.06431	FBXL2/CCL8/YTHDC2/CCNK/PPIB/VAPA	6
BP	GO:0051382	kinetochore assembly	6/2619	16/18670	0.01722	0.08575	0.06431	CENPE/MIS12/CENPT/CENPC/CENPF/POGZ	6
BP	GO:0070293	renal absorption	6/2619	16/18670	0.01722	0.08575	0.06431	MAGED2/KCNQ1/KLHL3/AKR1C3/HBB/HAS2	6
BP	GO:0071380	cellular response to prostaglandin E stimulus	6/2619	16/18670	0.01722	0.08575	0.06431	SFRP1/PPARG/PTGER4/TNFSF4/AKAP8/PRKAA1	6
BP	GO:0032781	positive regulation of ATPase activity	14/2619	55/18670	0.01737	0.0864	0.06481	ATP1B1/DNAL4/GABARAPL2/PFN2/DNAJC1/DNAJA1/MYL3/NCAPH/SETMAR/TOR1AIP1/MYL4/HSPA2/DNAJC24/NAPA	14
BP	GO:0002053	positive regulation of mesenchymal cell proliferation	8/2619	25/18670	0.01745	0.08653	0.0649	SIX1/STAT1/SOX9/FOXF1/LRP5/MYC/VEGFA/SMO	8
BP	GO:0019054	modulation by virus of host process	8/2619	25/18670	0.01745	0.08653	0.0649	BAD/KPNA2/CCL8/KPNB1/CCNK/KPNA1/KPNA3/VAPA	8
BP	GO:0033522	histone H2A ubiquitination	8/2619	25/18670	0.01745	0.08653	0.0649	SKP1/UBR2/TRIP12/PCGF1/DDB2/RYBP/RING1/UBR5	8
BP	GO:0061217	regulation of mesonephros development	8/2619	25/18670	0.01745	0.08653	0.0649	SIX1/SOX9/BMP4/AGT/SIX2/VEGFA/MAGED1/SMO	8
BP	GO:0019827	stem cell population maintenance	32/2619	157/18670	0.01777	0.08806	0.06605	MTF2/SFRP1/PTN/NOTCH1/CDH2/SOX9/NIPBL/ASPM/POLR2J/POLR2I/POLR2L/NCOA3/POLR2E/POLR2F/KIT/POLR2C/KDM3A/ARID1A/PCM1/SIX2/POLR2G/RBPJ/MED7/ZFP36L2/SMC1A/DPPA4/RAF1/MED27/PIWIL2/FZD7/SMO/HMGA2	32
BP	GO:0036294	cellular response to decreased oxygen levels	42/2619	217/18670	0.01779	0.08806	0.06605	SFRP1/PTN/NOTCH1/FAM162A/NDNF/CHCHD2/DDAH1/CCNA2/RORA/CFLAR/PSMB9/BAD/PINK1/STC1/BACH1/NOL3/KCNK3/PSMC2/PSMB6/CCNB1/PSMC3/MYC/TBL2/EGR1/RBPJ/PDK1/NAMPT/VEGFA/PSMD8/UBB/EGLN3/PSMB5/PSMD10/HIF1A/PRKAA1/SUV39H2/ACAA2/EP300/CUL2/ATF4/STC2/TWIST1	42
BP	GO:1903409	reactive oxygen species biosynthetic process	26/2619	122/18670	0.01793	0.08871	0.06654	GCH1/GCHFR/JAK2/SLC18A2/SNCA/CLU/SMAD3/DDAH1/RORA/RAB27A/CFLAR/CX3CR1/NQO1/INSR/DDAH2/IFNG/AGT/ASS1/TSPO/NOS3/TRAP1/P2RX4/SOD1/HBB/ATP2B4/PTK2B	26
BP	GO:0097164	ammonium ion metabolic process	40/2619	205/18670	0.01795	0.08871	0.06654	GCH1/AKR1B1/SPHK1/AKR1B10/PNPLA6/ALDH7A1/LIPC/PEMT/SNCA/SLC22A4/PLA2G2D/PLA2G15/COMT/AGMAT/SMS/PLA2G7/CSNK2B/ASAH1/PCTP/MOXD1/AKR7A2/PLA2G4C/APOC1/HDC/SNCAIP/ALDH9A1/AKR1C3/ACADM/SGMS1/SRM/PLBD1/HNMT/LPCAT4/CRAT/FABP3/AKR1C4/LPIN1/STARD7/CHPT1/TH	40
BP	GO:0050728	negative regulation of inflammatory response	34/2619	169/18670	0.01797	0.08871	0.06654	SLAMF8/TNFAIP3/CD200/TNFRSF1B/FNDC4/SMAD3/RORA/PTPRC/HGF/ADA/APOE/MAPK7/PPARG/GPX1/PTGER4/GPER1/PTPN2/ELANE/FOXF1/NFKB1/CDH5/C5orf30/IGF1/GHSR/MFHAS1/CUEDC2/CST7/SOD1/KRT1/NT5E/TYRO3/SERPINF1/MVK/NR1D2	34
BP	GO:0140056	organelle localization by membrane tethering	34/2619	169/18670	0.01797	0.08871	0.06654	CETN2/TCTN1/CEP135/CNTRL/NDE1/HAUS3/MOSPD3/TCTN3/RABEPK/DCTN3/HAUS2/C2CD3/STX10/VTI1B/SFI1/B9D1/FGFR1OP/DCTN2/VAMP3/TUBA4A/PCM1/CLASP1/DYNC1H1/IQCB1/CSNK1E/ALMS1/AKAP9/CDK1/SYT1/CEP290/CEP63/RAB15/OFD1/TCTN2	34
BP	GO:0072659	protein localization to plasma membrane	49/2619	260/18670	0.01801	0.08881	0.06661	GBP1/ATP1B1/TREM2/AR/CDH2/GAK/MACF1/PREPL/TNIK/TSPAN15/PID1/FGF13/MAP7/EGFR/PRNP/BSG/PRKCH/AP2M1/EHD3/VTI1B/ROCK1/ANK3/BBS1/GPER1/LAMA5/CD81/VAMP3/IFNG/PRKCI/RAB13/SEC16A/RAPGEF6/TMEM59/VAMP7/EFR3A/TMED2/OPTN/VAMP2/CACNB2/EMP2/RANGRF/CIB1/GOLGA4/LGALS3/GOLPH3/RAB15/FLNA/SORBS1/DPP6	49
BP	GO:0046165	alcohol biosynthetic process	35/2619	175/18670	0.01803	0.08884	0.06663	GCH1/AKR1B1/SPHK1/QDPR/LBR/PLCG2/SNCA/PMVK/GOT1/ERLIN2/PCBD1/PTH1R/APOE/ASAH1/MOXD1/GPER1/SC5D/NFKB1/IFNG/MBTPS1/PCK2/DHDDS/PLCE1/DHCR24/DHCR7/KPNB1/SOD1/PLCD1/PRKAA1/ISYNA1/CYB5R3/ACAA2/PTK2B/NFYC/MVK	35
BP	GO:0014009	glial cell proliferation	13/2619	50/18670	0.01804	0.08884	0.06663	PTN/NOTCH1/TREM2/CLU/PRKCH/PENK/CERS2/PRKCI/TSPO/IL6/NF2/CREB1/PTK2B	13
BP	GO:0042692	muscle cell differentiation	69/2619	385/18670	0.0181	0.08884	0.06663	SIX1/CXCL9/DYSF/SIK1/CXCL10/NOTCH1/PLEKHO1/CDH2/SOX9/IGFBP5/TMOD1/RORA/UCHL1/IL4R/CFLAR/DNMT1/CBY1/SGCB/SDC1/EZH2/SMARCD3/MYOM2/KIT/BIN1/RXRA/BMP4/SEMA4C/GPX1/GPER1/NEBL/ARID1A/MAML1/FOXF1/CD81/RGS4/AGT/MAPK11/CHUK/CTDP1/IGF1/COMP/TBX5/CCNB1/TMOD2/FHOD3/RBPJ/EREG/PDGFB/SORBS2/SORT1/VEGFA/PIN1/GLMN/CHRNB1/PPP3CA/CAMK1/TCF3/TNFSF14/AKAP13/CDK1/CXADR/TRIM32/XBP1/KRAS/CDK9/FZD7/SMO/MYH10/BDNF	69
BP	GO:0006563	L-serine metabolic process	5/2619	12/18670	0.01818	0.08884	0.06663	CBS/SDS/SERINC5/PSPH/SRR	5
BP	GO:0007077	mitotic nuclear envelope disassembly	5/2619	12/18670	0.01818	0.08884	0.06663	PRKCB/CCNB2/CCNB1/CDK1/LPIN1	5
BP	GO:0019336	phenol-containing compound catabolic process	5/2619	12/18670	0.01818	0.08884	0.06663	FAH/DIO3/COMT/MOXD1/DIO2	5
BP	GO:0038180	nerve growth factor signaling pathway	5/2619	12/18670	0.01818	0.08884	0.06663	NTF3/MAGI2/NTRK1/SORT1/BDNF	5
BP	GO:0043383	negative T cell selection	5/2619	12/18670	0.01818	0.08884	0.06663	PTPRC/CD28/ZAP70/CD3E/CCR7	5
BP	GO:0071888	macrophage apoptotic process	5/2619	12/18670	0.01818	0.08884	0.06663	CCL5/CCR5/IRF3/GHSR/NOD2	5
BP	GO:1900044	regulation of protein K63-linked ubiquitination	5/2619	12/18670	0.01818	0.08884	0.06663	TRIP12/BIRC2/PTPN22/NOD2/UBR5	5
BP	GO:1902224	ketone body metabolic process	5/2619	12/18670	0.01818	0.08884	0.06663	BDH2/SLC27A5/HMGCL/OXCT1/ACAT1	5
BP	GO:0006687	glycosphingolipid metabolic process	16/2619	66/18670	0.01823	0.08884	0.06663	CTSA/KIT/B3GALNT1/STS/ASAH1/UGCG/CLN6/HEXA/GM2A/NEU1/PRKAA1/FA2H/ST8SIA2/PSAP/CERK/B4GALT3	16
BP	GO:0046626	regulation of insulin receptor signaling pathway	16/2619	66/18670	0.01823	0.08884	0.06663	PTPRE/ENPP1/PRKCB/PID1/CDK4/SOCS1/OSBPL8/PTPN2/GRB10/MZB1/AGT/PRKCQ/OGT/PRKAA1/CISH/SORBS1	16
BP	GO:0048207	vesicle targeting, rough ER to cis-Golgi	16/2619	66/18670	0.01823	0.08884	0.06663	FOLR1/SEC24A/SERPINA1/PPP6R3/SEC22B/SEC13/F8/TRAPPC2L/CNIH1/TRAPPC10/SEC16A/TMED2/TMED10/ANKRD28/NAPA/CD59	16
BP	GO:0048208	COPII vesicle coating	16/2619	66/18670	0.01823	0.08884	0.06663	FOLR1/SEC24A/SERPINA1/PPP6R3/SEC22B/SEC13/F8/TRAPPC2L/CNIH1/TRAPPC10/SEC16A/TMED2/TMED10/ANKRD28/NAPA/CD59	16
BP	GO:0034976	response to endoplasmic reticulum stress	53/2619	285/18670	0.01834	0.08915	0.06686	NUPR1/MAP3K5/SDF2/THBS4/CLU/ATP6V0D1/KLHDC3/HERPUD1/ERLIN2/KDELR3/UBE2J1/NCK2/YIF1A/GSK3B/ATF3/DNAJB14/CASP4/CREB3/DDX11/RCN3/FBXO17/UBXN4/TATDN2/PTPN2/TMCO1/EXTL2/APAF1/MBTPS1/ATF6/ANKZF1/SEC16A/TBL2/MAN1B1/PML/EDEM1/NFE2L1/DNAJC3/UBXN8/TARDBP/ERP44/CXXC1/EP300/XBP1/CXCL8/CEBPB/ATF4/HSPA5/SEL1L/ASNS/STC2/DDIT3/USP14/UFC1	53
BP	GO:0002821	positive regulation of adaptive immune response	23/2619	105/18670	0.01834	0.08915	0.06686	HLA-C/TFRC/IL27RA/RIPK2/MALT1/HLA-F/HLA-G/HLA-A/PTPRC/ADA/HLA-B/HLA-E/CD28/CD40/CD81/IL6/XCL1/SLC11A1/TNFSF4/PRKCQ/IL6R/CCR2/FBXO38	23
BP	GO:0043266	regulation of potassium ion transport	23/2619	105/18670	0.01834	0.08915	0.06686	ATP1B1/TREM2/KCNQ1/NETO2/PRNP/BIN1/KLHL24/KCNJ2/ANK3/RGS4/CD63/NOS3/HCRT/VAMP2/KCNN2/AKAP9/CACNA1D/GAL/FLNA/PTK2B/ATF4/NEDD4L/DPP6	23
BP	GO:0055017	cardiac muscle tissue growth	23/2619	105/18670	0.01834	0.08915	0.06686	NOTCH1/JARID2/FOXC1/RBP4/PIM1/RXRA/FGF20/S1PR1/RGS4/ZFPM2/AGT/MAPK11/CTDP1/IGF1/TBX5/CCNB1/RBPJ/SORBS2/PIN1/AKAP13/CDK1/ERBB4/TENM4	23
BP	GO:0002828	regulation of type 2 immune response	9/2619	30/18670	0.01852	0.08972	0.06729	IL27RA/IL4R/IDO1/CD81/IL6/XCL1/TNFSF4/NOD2/CCR2	9
BP	GO:0048873	homeostasis of number of cells within a tissue	9/2619	30/18670	0.01852	0.08972	0.06729	NOTCH1/SOX9/F2R/NOS3/LIPA/KRAS/CCR2/SMO/FH	9
BP	GO:0070168	negative regulation of biomineral tissue development	9/2619	30/18670	0.01852	0.08972	0.06729	NOTCH1/SOX9/ENPP1/LTBP3/ROCK1/NOS3/HIF1A/PTK2B/SRGN	9
BP	GO:0071480	cellular response to gamma radiation	9/2619	30/18670	0.01852	0.08972	0.06729	ATR/CHEK2/ATM/CRYAB/EGR1/WRN/CDKN1A/TSPYL5/HSPA5	9
BP	GO:0045581	negative regulation of T cell differentiation	12/2619	45/18670	0.01858	0.08981	0.06736	IRF1/IL4R/CTLA4/RUNX3/SOCS1/BMP4/ERBB2/PTPN2/RC3H2/TNFSF4/HMGB1/PRDX2	12
BP	GO:0070316	regulation of G0 to G1 transition	12/2619	45/18670	0.01858	0.08981	0.06736	CDC7/SUZ12/HLA-G/CHEK1/EZH2/RRM2/MED1/APAF1/MGA/EED/RYBP/RING1	12
BP	GO:1900274	regulation of phospholipase C activity	12/2619	45/18670	0.01858	0.08981	0.06736	ITK/EGFR/NTRK2/NTF3/KIT/HTR2B/SELE/AGT/ANG/TXK/LPAR2/BDNF	12
BP	GO:0000724	double-strand break repair via homologous recombination	28/2619	134/18670	0.01861	0.08988	0.06742	CDC7/SMCHD1/NBN/NIPBL/RFWD3/RECQL/CHEK1/ATM/ZNF365/RPA1/SAMHD1/MMS19/RPA3/RNF138/SMC5/RMI1/BRCA2/UBQLN4/RAD51C/RAD50/SFPQ/NABP2/WRN/TIMELESS/SETD2/ACTR2/MORF4L1/RAD51B	28
BP	GO:0023061	signal release	81/2619	462/18670	0.01876	0.09055	0.06792	SFRP1/JAK2/CCL5/RPH3AL/SLC18A2/TACR2/SNCA/SRI/SLC25A4/RIMS3/PREPL/PRKCB/SYT11/MPC2/CD38/ARL2/RBP4/BAD/EGFR/SYNJ1/PFN2/MCTP1/GSK3B/HFE/EFNA5/HRH3/RAB11FIP1/GPER1/SYT17/TCIRG1/ARRB1/HADH/LIN7B/OXCT1/IFNG/ITPR2/CHRNA3/SIRT3/WLS/AGT/PTPRN2/CRHBP/LRP5/SNCAIP/HCRT/VAMP7/MAP4K4/IL6/GHSR/ADCY1/ARL2BP/ABCC8/CPE/ANO1/PPP3CA/SSTR5/VAMP2/CACNB2/LTBP4/HIF1A/TMF1/NMB/IL1RN/TARDBP/TAC1/GDF9/CACNA1D/RAF1/CREB1/GAL/RAB11B/TCF7L2/CCKAR/ENSA/SYT1/CRY1/INHBB/SYN1/RAP1B/NAPA/PASK	81
BP	GO:0097553	calcium ion transmembrane import into cytosol	29/2619	140/18670	0.01887	0.09079	0.06809	CXCL9/CXCL10/PLCG2/SNCA/SRI/CXCL11/PTPRC/PRNP/CCR5/NOL3/HTR2B/GPER1/F2R/LCK/ITPR2/MCOLN3/FAM155A/XCL1/CD19/CALCR/PLCE1/CCR7/LIME1/TPCN1/MCOLN1/ATP2B4/PTK2B/LETM1/DDIT3	29
BP	GO:0002369	T cell cytokine production	11/2619	40/18670	0.01892	0.09079	0.06809	TNFRSF1B/MALT1/HLA-F/HFE/DENND1B/CD81/IL6/XCL1/SLC11A1/TNFSF4/CCR2	11
BP	GO:2000008	regulation of protein localization to cell surface	11/2619	40/18670	0.01892	0.09079	0.06809	EGF/ASTN2/HFE/CD247/TYROBP/RANGRF/RAB11B/ERBB4/BDNF/LRIG2/NEDD4L	11
BP	GO:0002701	negative regulation of production of molecular mediator of immune response	10/2619	35/18670	0.01894	0.09079	0.06809	IRAK3/PARP3/ANGPT1/HLA-F/THOC1/HFE/CD96/XCL1/CUEDC2/IL13RA2	10
BP	GO:0006101	citrate metabolic process	10/2619	35/18670	0.01894	0.09079	0.06809	SDHC/ME2/IREB2/MDH2/SDHD/DLD/PDHB/SUCLG1/MDH1/FH	10
BP	GO:0030262	apoptotic nuclear changes	10/2619	35/18670	0.01894	0.09079	0.06809	DNASE1L3/GPER1/APAF1/IL6/DNASE2/HMGB1/TOP2A/KPNB1/DFFB/KPNA1	10
BP	GO:0042455	ribonucleoside biosynthetic process	10/2619	35/18670	0.01894	0.09079	0.06809	NME4/NME7/IMPDH2/NME5/ADK/ADA/NME3/GUK1/CTPS1/NT5E	10
BP	GO:0042462	eye photoreceptor cell development	10/2619	35/18670	0.01894	0.09079	0.06809	DIO3/NTRK2/BBS4/NAGLU/PRKCI/PRDM1/VEGFA/CEP290/NRL/TH	10
BP	GO:0097484	dendrite extension	10/2619	35/18670	0.01894	0.09079	0.06809	ITSN2/CYFIP2/CXCR4/SYT17/AUTS2/SYT1/CYFIP1/CPNE6/BCL11A/NEDD4L	10
BP	GO:0055123	digestive system development	30/2619	146/18670	0.01908	0.09131	0.06848	SFRP1/NOTCH1/CHD8/NIPBL/SMAD3/TCF7/EGFR/ADA/INSR/KIT/BMP4/WNT11/FOXF1/WLS/ASS1/SIX2/CCNB1/CDKN1C/CPS1/PRDM1/HIF1A/HOXA5/TYMS/ID2/HIP1R/CDKN1A/XBP1/COL3A1/CXCL8/SMO	30
BP	GO:1904892	regulation of STAT cascade	30/2619	146/18670	0.01908	0.09131	0.06848	AKR1B1/NOTCH1/JAK2/CCL5/CRLF1/IL15/IL7R/PTPRC/EGF/SOCS1/PECAM1/KIT/CTF1/CD40/PTPN2/F2R/IFNG/AGT/IGF1/CRLF3/IL6/ARL2BP/NLK/NF2/IL6R/GGNBP2/GHR/ERBB4/SH2B3/PTK2B	30
BP	GO:0032886	regulation of microtubule-based process	42/2619	218/18670	0.01913	0.09146	0.0686	PARP3/STMN2/SNCA/MACF1/ARL2/MDM1/CHEK1/FGF13/TPX2/GSK3B/CHORDC1/TPR/ERBB2/EFNA5/MAPRE3/SPAG5/ARHGEF2/BBS4/DRG1/CDH5/PLK2/KIF11/CHMP2A/TAOK1/CLASP1/DYNC1H1/SPAST/KATNB1/ALMS1/SMC1A/AKAP9/PRKAA1/CYLD/RANGRF/CIB1/CHMP1B/TACC3/KAT2B/MAPRE2/SPICE1/NUP62/TRIM58	42
BP	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	15/2619	61/18670	0.01925	0.09171	0.06879	TNFAIP3/SPHK1/BIRC3/TRAF1/ADAM17/CARD8/BIRC2/CASP4/MADD/NOL3/PTPN2/CHUK/CYLD/IKBKG/TRIM32	15
BP	GO:0030521	androgen receptor signaling pathway	15/2619	61/18670	0.01925	0.09171	0.06879	SFRP1/AR/NCOA3/DNAJA1/KDM3A/PHB/ARID1A/DAXX/BUD31/KAT5/NCOR1/HDAC1/RNF14/FHL2/EP300	15
BP	GO:0030888	regulation of B cell proliferation	15/2619	61/18670	0.01925	0.09171	0.06879	CD320/TFRC/PTPRC/CD38/GPR183/ATM/TNFRSF21/CTLA4/ADA/CD40/CD81/PELI1/MZB1/TYROBP/CDKN1A	15
BP	GO:0071384	cellular response to corticosteroid stimulus	15/2619	61/18670	0.01925	0.09171	0.06879	CFLAR/DDIT4/EGFR/STC1/GPER1/ASS1/AKR1C3/PCK2/CASP9/USP8/SSTR5/ZFP36L2/AKAP13/SERPINF1/ATP2B1	15
BP	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	15/2619	61/18670	0.01925	0.09171	0.06879	NUPR1/FIS1/FBXW7/BAD/NCK2/PTPN2/PRKRA/LCK/UBB/SFPQ/MCL1/SOD1/RAD9A/STYXL1/DDIT3	15
BP	GO:0060402	calcium ion transport into cytosol	32/2619	158/18670	0.01938	0.09214	0.06911	CXCL9/CXCL10/PLCG2/SNCA/SRI/CXCL11/PTPRC/PRNP/CCR5/NOL3/HTR2B/GPER1/F2R/LCK/ITPR2/MCOLN3/PML/FAM155A/XCL1/CD19/P2RX4/CALCR/PLCE1/CCR7/LIME1/TPCN1/MCOLN1/ATP2B4/MS4A1/PTK2B/LETM1/DDIT3	32
BP	GO:0031331	positive regulation of cellular catabolic process	65/2619	361/18670	0.01938	0.09214	0.06911	TNFAIP3/NUPR1/CEBPA/TREM2/TNFRSF1B/FBXW7/MAPK3/RIPK2/VPS13C/TBK1/SNCA/CLU/HERPUD1/TRIM22/CBFA2T3/FTO/ATM/BAD/EGF/UVRAG/PINK1/APOE/GSK3B/INSR/CHFR/ZC3HAV1/PSMC2/PIM2/ROCK1/PFKFB3/ADRB2/CD81/IFNG/PRR5L/PLK2/TRIB1/TRIM21/PIK3CB/IGF1/DET1/KDR/TMEM59/IL6/POLR2G/CSNK1A1/MTDH/RNF19B/HMGB1/CSNK1E/EDEM1/OPTN/KAT5/ZFP36L2/PSMD10/HIF1A/TPCN1/PRKAA1/NOD1/IKBKG/RNF14/SESN1/PTK2B/HNRNPD/CLEC16A/TWIST1	65
BP	GO:1901222	regulation of NIK/NF-kappaB signaling	25/2619	117/18670	0.01939	0.09214	0.06911	NFKBIA/SPHK1/TREM2/AKIP1/TRIP6/MALT1/EGFR/BIRC2/COPS8/TSPAN6/NOL3/PTPN22/RC3H2/CD27/CARD14/NR3C2/HMGB1/NOD2/PPM1B/LIME1/AGO3/CYLD/NOD1/TNFSF14/EP300	25
BP	GO:0071559	response to transforming growth factor beta	48/2619	255/18670	0.01945	0.09237	0.06928	SFRP1/FOLR1/SOX9/FNDC4/SMAD3/GOT1/CFLAR/MTMR4/ADAM17/LTBP3/TRIM33/CX3CR1/RUNX3/HTRA1/MAPK7/ING2/GDF5/PENK/ADAMTSL2/RNF111/ZNF451/HPGD/ROCK1/MXRA5/FERMT2/POSTN/CDH5/APAF1/CDKN1C/CILP/PML/XCL1/PIN1/FUT8/UBB/FERMT1/NLK/ZFP36L2/PTPRK/LTBP4/USP9X/GDF9/ITGB5/CREB1/EP300/COL3A1/COL4A2/HSPA5	48
BP	GO:0006633	fatty acid biosynthetic process	33/2619	164/18670	0.01947	0.09239	0.0693	HPGDS/LTC4S/PTGS1/TBXAS1/LIPC/THNSL2/ALOX5AP/EPHX2/ACSM5/ERLIN2/TECR/DECR2/MECR/PRKAG1/GSTM4/PRKAB1/HPGD/GPX4/APOC1/WDTC1/SCD5/NR1H2/AKR1C3/PTGDS/LPL/PRKAA1/FA2H/MCAT/EIF6/XBP1/CBR1/PLP1/ABHD2	33
BP	GO:0044262	cellular carbohydrate metabolic process	53/2619	286/18670	0.01952	0.09246	0.06935	FGGY/AKR1B1/DYSF/SIK1/PDK2/NUPR1/PPP1R3C/ENPP1/GUSB/RBKS/SNCA/GOT1/RORA/CBFA2T3/DDIT4/PTH1R/BAD/SYNJ1/PGM1/EXT2/GSK3B/INSR/GNPTAB/IGFBP4/SORD/DYRK2/GK/LCMT1/SLC5A3/RANBP2/PFKFB3/GPER1/FAM3A/PTPN2/PYGM/EXTL2/IGF1/PDK1/PCK2/NFE2L1/GAA/OGT/HAS2/ISYNA1/KAT2B/INPP5E/COQ2/EP300/CRY1/PTK2B/RPE/PASK/SORBS1	53
BP	GO:0045913	positive regulation of carbohydrate metabolic process	19/2619	83/18670	0.01953	0.09246	0.06935	SNCA/PTH1R/BAD/EGF/INSR/DYRK2/RANBP2/PFKFB3/GPER1/PTPN2/NFKB1/IFNG/IGF1/PDGFB/HIF1A/PRKAA1/HAS2/KAT2B/SORBS1	19
BP	GO:0006022	aminoglycan metabolic process	34/2619	170/18670	0.01953	0.09246	0.06935	FUCA1/GPC5/NDNF/UST/GUSB/ANGPT1/IL15/FOXC1/HGF/SDC1/B4GALT2/EGF/PIM1/EXT2/ITIH4/HMMR/NAGLU/CD44/CLN6/NFKB1/HEXA/ST3GAL2/CHST15/EXTL2/B4GALT7/PDGFB/SPOCK2/HAS2/VCAN/SGSH/CHST12/KERA/ARSB/B4GALT3	34
BP	GO:0061138	morphogenesis of a branching epithelium	36/2619	182/18670	0.01956	0.09255	0.06941	SIX1/HOXA11/SFRP1/NOTCH1/AR/SOX9/PGF/HGF/SEMA3A/EGF/CTNNBIP1/NOTCH4/RXRA/BMP4/LEF1/MED1/LAMA5/FOXF1/RBM15/AGT/LRP5/SIX2/MYC/RASIP1/PML/VEGFA/PLXND1/MAGED1/SEMA3E/HOXA5/TIMELESS/PLXNA1/COL4A1/FKBPL/KRAS/SMO	36
BP	GO:0090114	COPII-coated vesicle budding	17/2619	72/18670	0.01966	0.09294	0.06971	FOLR1/SEC24A/SERPINA1/PPP6R3/SEC22B/SEC13/F8/TRAPPC2L/CNIH1/TRAPPC10/SEC16A/TMED2/TMED10/ANKRD28/VAPA/NAPA/CD59	17
BP	GO:0032872	regulation of stress-activated MAPK cascade	45/2619	237/18670	0.02004	0.09468	0.07102	TPD52L1/SFRP1/SPHK1/MAP3K5/RASGRP1/MAPK3/RIPK2/SLAMF1/FAS/TNIK/HGF/SEMA3A/EGFR/MAP3K11/PINK1/TNFRSF11A/BIRC7/SEMA4C/DNAJA1/PTPN22/MAP4K1/FOXM1/CD27/DAXX/MYC/TAOK1/MAP4K4/EPHA4/MFHAS1/VEGFA/HMGB1/CCR7/NOD2/ARL6IP5/MAP3K3/NCOR1/CYLD/IL1RN/TAOK3/NOD1/PHLPP1/PTK2B/FZD7/CD40LG/NCF1	45
BP	GO:0006639	acylglycerol metabolic process	27/2619	129/18670	0.02014	0.09509	0.07132	PNPLA4/SIK1/LIPC/FBXW7/SLC22A4/ABHD6/AGPAT5/APOE/DGKA/SLC27A5/GK/GPX1/CAT/APOC1/DGKZ/NR1H2/ANG/CPS1/PCK2/PLCE1/LPL/FABP7/FABP3/ABHD2/LPIN1/SEL1L/LMF1	27
BP	GO:0031295	T cell costimulation	14/2619	56/18670	0.02025	0.09547	0.07161	CTLA4/TNFRSF14/CD28/MAP3K8/CD81/CD3E/LCK/EFNB1/TNFSF4/CCR7/TNFSF14/PAK2/CD40LG/PIK3CA	14
BP	GO:1903202	negative regulation of oxidative stress-induced cell death	14/2619	56/18670	0.02025	0.09547	0.07161	SLC7A11/HGF/NME5/PINK1/MAPK7/NOL3/GPX1/HSPB1/TRAP1/HIF1A/VNN1/PYCR1/ATF4/PSAP	14
BP	GO:0033157	regulation of intracellular protein transport	43/2619	225/18670	0.02039	0.09582	0.07187	ZIC1/LCP1/ECT2/FIS1/FBXW7/ANGPT1/SMAD3/MICALL2/BARD1/UBE2J1/PRNP/PINK1/GSK3B/TPR/BMP4/ERBB2/TMEM30A/ANK3/CD81/IFNG/PRR5L/PCM1/RAC2/SEC16A/VAMP7/FERMT1/ATG13/EDEM1/VAMP2/CAMK1/PRKAA1/SETD2/TARDBP/CIB1/GTSE1/TCF7L2/CEP290/NUCB1/UBL5/FLNA/UBR5/SMO/NUP62	43
BP	GO:0000725	recombinational repair	28/2619	135/18670	0.02043	0.09582	0.07187	CDC7/SMCHD1/NBN/NIPBL/RFWD3/RECQL/CHEK1/ATM/ZNF365/RPA1/SAMHD1/MMS19/RPA3/RNF138/SMC5/RMI1/BRCA2/UBQLN4/RAD51C/RAD50/SFPQ/NABP2/WRN/TIMELESS/SETD2/ACTR2/MORF4L1/RAD51B	28
BP	GO:0009081	branched-chain amino acid metabolic process	7/2619	21/18670	0.02043	0.09582	0.07187	IVD/BCKDHB/HSD17B10/HMGCL/ACAT1/DLD/ALDH6A1	7
BP	GO:0009083	branched-chain amino acid catabolic process	7/2619	21/18670	0.02043	0.09582	0.07187	IVD/BCKDHB/HSD17B10/HMGCL/ACAT1/DLD/ALDH6A1	7
BP	GO:0031498	chromatin disassembly	7/2619	21/18670	0.02043	0.09582	0.07187	SMARCD3/SET/ARID1A/PBRM1/SMARCD2/PADI2/HMGA1	7
BP	GO:0032986	protein-DNA complex disassembly	7/2619	21/18670	0.02043	0.09582	0.07187	SMARCD3/SET/ARID1A/MYC/PBRM1/SMARCD2/HMGA1	7
BP	GO:0072111	cell proliferation involved in kidney development	7/2619	21/18670	0.02043	0.09582	0.07187	STAT1/CFLAR/BMP4/MYC/EGR1/PDGFB/IL6R	7
BP	GO:0097306	cellular response to alcohol	20/2619	89/18670	0.02048	0.09598	0.07199	SFRP1/GRAMD1C/CDK4/FDX1/EFNA5/PPARG/PTGER4/PTGFR/MAP4K1/ITPR2/AKR1C3/ADCY1/TNFSF4/NFE2L1/AKAP8/PRKAA1/ADCY2/CCL7/SMO/ATP2B1	20
BP	GO:0071456	cellular response to hypoxia	40/2619	207/18670	0.02082	0.0975	0.07313	SFRP1/PTN/NOTCH1/FAM162A/NDNF/CHCHD2/DDAH1/CCNA2/RORA/CFLAR/PSMB9/BAD/PINK1/STC1/BACH1/NOL3/KCNK3/PSMC2/PSMB6/CCNB1/PSMC3/MYC/TBL2/EGR1/RBPJ/PDK1/VEGFA/PSMD8/UBB/EGLN3/PSMB5/PSMD10/HIF1A/PRKAA1/SUV39H2/ACAA2/EP300/CUL2/STC2/TWIST1	40
BP	GO:0042246	tissue regeneration	18/2619	78/18670	0.02092	0.09768	0.07326	SGCA/DYSF/PTN/NOTCH1/CFLAR/NINJ2/EZH2/GPX1/CPQ/CD81/POSTN/IGF1/CCNB1/PPP3CA/NINJ1/CDKN1A/ERBB4/FZD7	18
BP	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	18/2619	78/18670	0.02092	0.09768	0.07326	PDK2/NUPR1/CHEK2/DDIT4/ING2/DYRK2/HNRNPK/PPP1R13B/FHIT/CD44/TP53BP2/BRCA2/TAF9B/PML/UBB/IFI16/CDKN1A/EP300	18
BP	GO:0051298	centrosome duplication	16/2619	67/18670	0.02092	0.09768	0.07326	CETN2/CEP135/NDE1/MDM1/CHORDC1/C2CD3/PLK2/CHMP2A/BRCA2/KIAA0753/ALMS1/CHMP1B/KAT2B/CEP63/SPICE1/NUP62	16
BP	GO:0002065	columnar/cuboidal epithelial cell differentiation	24/2619	112/18670	0.02095	0.09768	0.07326	NOTCH1/CDH2/TMEM231/BAD/SERPINE1/GSK3B/RXRA/BMP4/WNT11/LEF1/B9D1/MCOLN3/INSM1/RBPJ/PRDM1/SOD1/JAG2/HIF1A/HOXA5/TYMS/CDKN1A/SLC4A7/CEBPB/SMO	24
BP	GO:0060419	heart growth	24/2619	112/18670	0.02095	0.09768	0.07326	NOTCH1/JARID2/DUSP6/FOXC1/RBP4/PIM1/RXRA/FGF20/S1PR1/RGS4/ZFPM2/AGT/MAPK11/CTDP1/IGF1/TBX5/CCNB1/RBPJ/SORBS2/PIN1/AKAP13/CDK1/ERBB4/TENM4	24
BP	GO:1903510	mucopolysaccharide metabolic process	24/2619	112/18670	0.02095	0.09768	0.07326	NDNF/UST/GUSB/ANGPT1/IL15/HGF/B4GALT2/EGF/PIM1/ITIH4/HMMR/CD44/NFKB1/HEXA/ST3GAL2/CHST15/PDGFB/SPOCK2/HAS2/VCAN/CHST12/KERA/ARSB/B4GALT3	24
BP	GO:0062013	positive regulation of small molecule metabolic process	31/2619	153/18670	0.02099	0.09777	0.07333	NUPR1/TREM2/SNCA/PID1/PTH1R/EGF/COMT/PINK1/INSR/DYRK2/PPARG/PFKFB3/GPER1/TAZ/GUCA1A/PTPN2/NFKB1/IFNG/IGF1/NOS3/CCNB1/NR1H2/GHSR/PDGFB/HIF1A/PRKAA1/HAS2/CDK1/KAT2B/TWIST1/SORBS1	31
BP	GO:0030072	peptide hormone secretion	47/2619	250/18670	0.02101	0.09777	0.07333	SFRP1/JAK2/CCL5/RPH3AL/TACR2/SRI/SLC25A4/MPC2/CD38/ARL2/RBP4/BAD/EGFR/HFE/EFNA5/GPER1/TCIRG1/ARRB1/HADH/OXCT1/IFNG/ITPR2/SIRT3/PTPRN2/CRHBP/LRP5/MAP4K4/IL6/GHSR/ARL2BP/ABCC8/CPE/ANO1/PPP3CA/SSTR5/LTBP4/HIF1A/IL1RN/TARDBP/CACNA1D/RAF1/GAL/RAB11B/TCF7L2/ENSA/INHBB/PASK	47
BP	GO:0006665	sphingolipid metabolic process	32/2619	159/18670	0.02109	0.0981	0.07358	SPHK1/PRKD2/PEMT/PLA2G15/TECR/CTSA/CERS6/PRKD3/KIT/B3GALNT1/STS/ASAH1/CERS4/UGCG/SERINC5/CLN6/HEXA/CERS2/GM2A/ALDH3A2/NEU1/SGMS1/PRKAA1/FA2H/ST8SIA2/SGPL1/VAPA/PSAP/ALDH3B1/CERK/TH/B4GALT3	32
BP	GO:0007093	mitotic cell cycle checkpoint	33/2619	165/18670	0.02116	0.09821	0.07366	TOPBP1/NBN/RFWD3/CRADD/CHEK2/ATM/CHFR/TPR/BUB1B/LCMT1/DONSON/SETMAR/KNTC1/NDC80/PLK2/CCNB1/TAOK1/PML/CDC20/AURKB/TOP2A/NABP2/TAOK3/GTSE1/CDK1/RAD9A/CDKN1A/WEE1/ATF2/EP300/HMGA2/CENPF/RBL2	33
BP	GO:0071695	anatomical structure maturation	33/2619	165/18670	0.02116	0.09821	0.07366	CDC25B/SEMA4D/CX3CR1/EPB42/S1PR1/CDH5/NPR2/PTBP3/IGF1/CCNB1/ANG/CDKN1C/BRCA2/RBPJ/MYOC/EREG/MTCH1/FERMT1/IRX5/HIF1A/HOXA5/ERCC2/SIX3/TYMS/GAL/CDKN1A/XBP1/PTK2B/BCL11A/DDIT3/DAZL/TRIM58/FBXO5	33
BP	GO:0048469	cell maturation	35/2619	177/18670	0.02119	0.09821	0.07366	CDC25B/CEBPA/IL15/PTH1R/EPB42/PPARG/TUSC2/NPR2/PTBP3/DLD/CCNB1/ANG/CDKN1C/BRCA2/MYOC/AXL/EREG/VEGFA/MTCH1/IRX5/HIF1A/HOXA5/ERCC2/SIX3/TYMS/ID2/GAL/CDKN1A/XBP1/PTK2B/ABHD2/BCL11A/DAZL/TRIM58/FBXO5	35
BP	GO:0050999	regulation of nitric-oxide synthase activity	13/2619	51/18670	0.02119	0.09821	0.07366	GCH1/DDAH1/EGFR/APOE/HTR2B/DDAH2/NOS3/S100A1/HIF1A/ATP2B4/NOD1/KRAS/PTK2B	13
BP	GO:0072523	purine-containing compound catabolic process	13/2619	51/18670	0.02119	0.09821	0.07366	PDE1A/NT5C2/ADA/SAMHD1/NUDT9/GPX1/PNP/NUDT11/ACAT1/AHCY/DNPH1/NT5E/AMPD3	13
BP	GO:0042100	B cell proliferation	21/2619	95/18670	0.02132	0.09871	0.07403	CD320/TFRC/IL7R/PTPRC/CD38/GPR183/ATM/TNFRSF21/CTLA4/ADA/LEF1/CD40/CD81/PELI1/MZB1/TYROBP/CD19/CTPS1/CDKN1A/MS4A1/CD40LG	21
BP	GO:0042445	hormone metabolic process	44/2619	232/18670	0.02166	0.1002	0.07519	AKR1B1/PNPLA4/DIO3/AKR1B10/CPA3/ALDH1A1/PCSK1/DHRS3/DHRS9/RBP4/HSD11B2/DDO/COMT/HSD17B1/FDX1/CYP11A1/HFE/IDE/PCSK7/MED1/CMA1/PLEKHA1/CPQ/NFKB1/YWHAH/IFNG/TSPO/ALDH9A1/EGR1/AKR1C3/ALDH1A3/CPE/DIO2/DHCR7/HIF1A/HSD17B14/CTSG/GAL/TCF7L2/GHR/SGPL1/AKR1C4/STC2/CORIN	44
BP	GO:0008637	apoptotic mitochondrial changes	26/2619	124/18670	0.02181	0.1008	0.07562	FAM162A/EYA2/FIS1/CLU/SLC25A4/HGF/BAD/PINK1/GSK3B/NOL3/GZMB/TMEM14A/PIM2/GPX1/PPP1R13B/GPER1/YWHAH/IGF1/TP53BP2/CIDEB/GGCT/PSMD10/ACAA2/HIP1R/ATF2/ERBB4	26
BP	GO:0030810	positive regulation of nucleotide biosynthetic process	12/2619	46/18670	0.02202	0.1014	0.07603	TREM2/PID1/PINK1/INSR/PFKFB3/TAZ/GUCA1A/IFNG/IGF1/NOS3/HIF1A/PRKAA1	12
BP	GO:0032480	negative regulation of type I interferon production	12/2619	46/18670	0.02202	0.1014	0.07603	TNFAIP3/RNF125/TBK1/REL/NMI/IRF3/RELB/GPATCH3/PIN1/PPM1B/CYLD/UBE2L6	12
BP	GO:0071675	regulation of mononuclear cell migration	12/2619	46/18670	0.02202	0.1014	0.07603	SLAMF8/CXCL10/LGMN/CCL5/MAPK3/SERPINE1/CREB3/PLA2G7/NBL1/HMGB1/LGALS3/CCR2	12
BP	GO:0097720	calcineurin-mediated signaling	12/2619	46/18670	0.02202	0.1014	0.07603	CAMTA1/PRNP/GSK3B/MAPK7/DYRK2/IGF1/HOMER3/PPP3CA/ATP2B4/CIB1/FHL2/NR5A2	12
BP	GO:1900373	positive regulation of purine nucleotide biosynthetic process	12/2619	46/18670	0.02202	0.1014	0.07603	TREM2/PID1/PINK1/INSR/PFKFB3/TAZ/GUCA1A/IFNG/IGF1/NOS3/HIF1A/PRKAA1	12
BP	GO:1904036	negative regulation of epithelial cell apoptotic process	12/2619	46/18670	0.02202	0.1014	0.07603	TNFAIP3/NUPR1/NDNF/ANGPT1/TNIP2/CFLAR/SERPINE1/MAPK7/KRIT1/KDR/SCG2/TCF7L2	12
BP	GO:0000018	regulation of DNA recombination	22/2619	101/18670	0.02204	0.1014	0.07603	PARP3/SMCHD1/TFRC/IL27RA/IL7R/PTPRC/CHEK1/KPNA2/ZNF365/THOC1/MMS19/CD28/CD40/TNFSF4/UBQLN4/RAD50/WRN/ERCC2/TIMELESS/SETD2/KPNA1/ACTR2	22
BP	GO:0006997	nucleus organization	27/2619	130/18670	0.02213	0.1015	0.07615	SRPK1/PRKCB/ATXN7/NUP153/TPR/BIN1/USPL1/KDM3A/GPER1/CHMP6/POLR1B/TOR1AIP1/BANF1/CCNB2/CHMP2A/CCNB1/PML/ANKLE2/NFE2L1/SPAST/TMF1/NDC1/TARDBP/CHMP1B/CDK1/LPIN1/NUP98	27
BP	GO:0001916	positive regulation of T cell mediated cytotoxicity	8/2619	26/18670	0.02218	0.1015	0.07615	HLA-C/HLA-F/HLA-G/HLA-A/PTPRC/HLA-B/HLA-E/XCL1	8
BP	GO:0006309	apoptotic DNA fragmentation	8/2619	26/18670	0.02218	0.1015	0.07615	DNASE1L3/APAF1/IL6/DNASE2/HMGB1/KPNB1/DFFB/KPNA1	8
BP	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway	8/2619	26/18670	0.02218	0.1015	0.07615	AR/IGFBP5/IGFBP2/IGFBP4/PHIP/IGF1/GHSR/CILP	8
BP	GO:0060740	prostate gland epithelium morphogenesis	8/2619	26/18670	0.02218	0.1015	0.07615	SFRP1/NOTCH1/AR/SOX9/RXRA/BMP4/CYP7B1/ID4	8
BP	GO:0032835	glomerulus development	15/2619	62/18670	0.0222	0.1015	0.07615	NOTCH1/ANGPT1/CFLAR/FOXC1/ANGPT2/PECAM1/BMP4/MAGI2/EGR1/PDGFB/PLCE1/IL6R/MPV17/GPR4/PODXL	15
BP	GO:1905268	negative regulation of chromatin organization	15/2619	62/18670	0.0222	0.1015	0.07615	MTF2/JARID2/KDM5A/SNCA/DNMT1/TRIP12/ATAD2B/SET/ZNF451/KDM3A/TAF7/ATAD2/UBR5/HMGA1/TWIST1	15
BP	GO:1905818	regulation of chromosome separation	15/2619	62/18670	0.0222	0.1015	0.07615	ATM/DLGAP5/PTTG1/TPR/BUB1B/LCMT1/NDC80/CENPE/CCNB1/CDC20/AURKB/TACC3/PTTG2/CENPF/FBXO5	15
BP	GO:1903050	regulation of proteolysis involved in cellular protein catabolic process	41/2619	214/18670	0.02223	0.1016	0.0762	NUPR1/CEBPA/TREM2/FBXW7/CLU/LAMP3/HERPUD1/GABARAPL2/CBFA2T3/UBE2J1/EGF/PINK1/APOE/GSK3B/CHFR/HFE/PSMC2/GPX1/FHIT/PLK2/TRIB1/DET1/PML/EPHA4/CSNK1A1/RNF19B/UBB/UBQLN4/GLMN/CSNK1E/EDEM1/NFE2L1/PSMD10/TMF1/OGT/RYBP/RNF14/N4BP1/PTK2B/CLEC16A/USP14	41
BP	GO:0045685	regulation of glial cell differentiation	17/2619	73/18670	0.02237	0.102	0.07653	PTN/NOTCH1/TNFRSF1B/TNFRSF21/ZNF365/PRMT5/BIN1/PPARG/CXCR4/ID4/IL6/EPHA4/HDAC1/CDK1/OLIG2/ID2/TENM4	17
BP	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	17/2619	73/18670	0.02237	0.102	0.07653	CXCL9/CXCL10/CXCL13/CXCL11/CXCL2/FAM3A/ELANE/GNLY/DEFA6/HMGN2/CXCL3/CCL13/DEFA5/S100A12/CXCL8/DEFB126/REG3A	17
BP	GO:1903779	regulation of cardiac conduction	17/2619	73/18670	0.02237	0.102	0.07653	ATP1B1/FXYD1/ATP2A3/SRI/FXYD6/EHD3/ASPH/ITPR2/NPR2/ATP2B2/AGT/RANGRF/ATP2B4/CXADR/FLNA/ATP2B1/CORIN	17
BP	GO:0010675	regulation of cellular carbohydrate metabolic process	29/2619	142/18670	0.02259	0.1029	0.07719	SIK1/PDK2/NUPR1/ENPP1/SNCA/RORA/CBFA2T3/DDIT4/PTH1R/BAD/GSK3B/INSR/IGFBP4/DYRK2/LCMT1/RANBP2/GPER1/FAM3A/PTPN2/IGF1/PDK1/NFE2L1/OGT/KAT2B/EP300/CRY1/PTK2B/PASK/SORBS1	29
BP	GO:0030330	DNA damage response, signal transduction by p53 class mediator	23/2619	107/18670	0.02265	0.1029	0.07719	NBN/ATR/CRADD/CHEK2/ATM/CD44/SMYD2/FOXM1/PLK2/CCNB1/BRCA2/PML/ATRX/PLA2R1/BATF/KAT5/PSMD10/GTSE1/CDK1/CDKN1A/EP300/TWIST1/RBL2	23
BP	GO:0070317	negative regulation of G0 to G1 transition	11/2619	41/18670	0.02267	0.1029	0.07719	CDC7/SUZ12/HLA-G/CHEK1/EZH2/RRM2/APAF1/MGA/EED/RYBP/RING1	11
BP	GO:0090224	regulation of spindle organization	11/2619	41/18670	0.02267	0.1029	0.07719	PARP3/TPX2/TPR/SPAG5/DRG1/CHMP2A/DYNC1H1/SMC1A/CHMP1B/TACC3/NUP62	11
BP	GO:0006694	steroid biosynthetic process	38/2619	196/18670	0.02267	0.1029	0.07719	AKR1B1/CYB5R1/LBR/CH25H/PMVK/OSBPL3/ACOX2/ERLIN2/HSD11B2/APOE/HSD17B1/SLC27A5/FDX1/CYP11A1/CYP7B1/MED1/ASAH1/SC5D/NFKB1/IFNG/MBTPS1/TSPO/SCP2/EGR1/AKR1C3/DHCR24/DHCR7/KPNB1/SOD1/HSD17B14/PRKAA1/CYB5R3/ACAA2/ACOT8/AKR1C4/NFYC/MVK/ACBD3	38
BP	GO:0071897	DNA biosynthetic process	38/2619	196/18670	0.02267	0.1029	0.07719	SPHK1/PARP3/PRKD2/TK2/MAPK3/HNRNPA2B1/POLD2/ATR/TNKS2/HGF/ATM/NHP2/RPA1/RPA3/POLD4/PPARG/PHB/DCP2/POLG/MYC/PDGFB/HMBOX1/AURKB/HNRNPA1/PARP4/UBB/PRKCQ/RAD50/DTL/WRN/TYMS/UBE2L6/PARM1/CDKN1A/PTK2B/HNRNPD/RFC2/CENPF	38
BP	GO:0006816	calcium ion transport	76/2619	434/18670	0.02279	0.1031	0.07734	CXCL9/DYSF/CXCL10/ATP1B1/CCL5/ATP2A3/PLCG2/SNCA/SRI/CXCL11/PRKCB/LILRB2/PTPRC/FGF14/LILRA2/EGF/ATP2C1/PRNP/STC1/BIN1/CCR5/NOL3/HTR2B/EHD3/PHB/GPER1/CXCR4/TSPAN13/GPM6A/F2R/TMCO1/CCL8/LCK/ITPR2/RGS4/MCOLN3/ATP2B2/AGT/TSPO/NOS3/S100A1/HCRT/PML/FAM155A/PDGFB/XCL1/CD19/P2RX4/CALCR/PLCE1/PKD2L1/CCR7/HOMER3/MICU1/PPP3CA/CACNB2/ORAI3/REM1/LIME1/TPCN1/MCOLN1/ATP2B4/CACNA1D/TRPV2/LGALS3/HSPA2/CACNA2D3/MS4A1/YME1L1/PTK2B/STOML2/LETM1/CAMK2B/STC2/ATP2B1/DDIT3	76
BP	GO:0010770	positive regulation of cell morphogenesis involved in differentiation	31/2619	154/18670	0.02286	0.1031	0.07734	SEMA4D/MACF1/SS18L1/TUBB2B/BAIAP2/NTRK2/NEDD9/EFNA5/TRAK1/PARP6/ARHGEF7/VAMP7/RND2/MYOC/EPHA4/VEGFA/PLXND1/HAS2/CIB1/GOLGA4/NGFR/TRPV2/CDKL5/PLXNA1/CYFIP1/CAPRIN2/FLNA/DSCAM/CAMK2B/ACTR2/BDNF	31
BP	GO:0048639	positive regulation of developmental growth	36/2619	184/18670	0.02286	0.1031	0.07734	NOTCH1/DIO3/SEMA4D/NIPBL/MACF1/ITSN2/PIM1/INSR/EFNA5/BBS4/CXCR4/SYT17/ZFPM2/IGF1/TBX5/CCNB1/RND2/GHSR/RBPJ/VEGFA/PIN1/GOLGA4/PPIB/TRPV2/CREB1/CDK1/CDKL5/GHR/SYT1/ERBB4/CYFIP1/DSCAM/SMO/CPNE6/BDNF/NEDD4L	36
BP	GO:0022406	membrane docking	35/2619	178/18670	0.02292	0.1031	0.07734	CETN2/TCTN1/CEP135/CNTRL/NDE1/HAUS3/MOSPD3/TCTN3/RABEPK/DCTN3/HAUS2/C2CD3/STX10/VTI1B/SFI1/ROCK1/B9D1/FGFR1OP/DCTN2/VAMP3/TUBA4A/PCM1/CLASP1/DYNC1H1/IQCB1/CSNK1E/ALMS1/AKAP9/CDK1/SYT1/CEP290/CEP63/RAB15/OFD1/TCTN2	35
BP	GO:0002724	regulation of T cell cytokine production	9/2619	31/18670	0.02293	0.1031	0.07734	TNFRSF1B/MALT1/HLA-F/HFE/CD81/IL6/XCL1/TNFSF4/CCR2	9
BP	GO:0007143	female meiotic nuclear division	9/2619	31/18670	0.02293	0.1031	0.07734	CDC25B/ATM/NCAPH/EREG/UBB/RAD51C/TOP2A/DAZL/FBXO5	9
BP	GO:0034694	response to prostaglandin	9/2619	31/18670	0.02293	0.1031	0.07734	SFRP1/PPARG/PTGER4/PTGFR/AKR1C3/TNFSF4/CCR7/AKAP8/PRKAA1	9
BP	GO:0044319	wound healing, spreading of cells	9/2619	31/18670	0.02293	0.1031	0.07734	ADAM17/ITGA5/CD44/HBEGF/CLASP1/CD151/MMP12/ARHGAP35/FLNA	9
BP	GO:0090505	epiboly involved in wound healing	9/2619	31/18670	0.02293	0.1031	0.07734	ADAM17/ITGA5/CD44/HBEGF/CLASP1/CD151/MMP12/ARHGAP35/FLNA	9
BP	GO:0070302	regulation of stress-activated protein kinase signaling cascade	45/2619	239/18670	0.02294	0.1031	0.07734	TPD52L1/SFRP1/SPHK1/MAP3K5/RASGRP1/MAPK3/RIPK2/SLAMF1/FAS/TNIK/HGF/SEMA3A/EGFR/MAP3K11/PINK1/TNFRSF11A/BIRC7/SEMA4C/DNAJA1/PTPN22/MAP4K1/FOXM1/CD27/DAXX/MYC/TAOK1/MAP4K4/EPHA4/MFHAS1/VEGFA/HMGB1/CCR7/NOD2/ARL6IP5/MAP3K3/NCOR1/CYLD/IL1RN/TAOK3/NOD1/PHLPP1/PTK2B/FZD7/CD40LG/NCF1	45
BP	GO:0051262	protein tetramerization	34/2619	172/18670	0.02295	0.1031	0.07734	CCL5/SNCA/SYT11/PCBD1/CBY1/IMPDH2/HSD17B10/ACOT13/INSR/KRT10/GPX3/RRM2/DPYS/IDE/HMGCL/RXRA/SAMHD1/KCNJ2/CPSF7/CAT/PFKM/ALDH9A1/CRYZ/CD247/ALDH1A3/PKD2L1/PEX14/SRR/AQP2/MCOLN1/KRT1/CUTC/CRTC3/MS4A1	34
BP	GO:0001656	metanephros development	20/2619	90/18670	0.02297	0.1031	0.07734	SIX1/AKR1B1/HOXA11/STAT1/SOX9/NIPBL/BMP4/OSR2/ACAT1/SIX2/MYC/EGR1/PDGFB/CXCR2/AQP2/ID2/ID3/HOXC11/SMO/APH1A	20
BP	GO:0032733	positive regulation of interleukin-10 production	10/2619	36/18670	0.02302	0.1031	0.07734	TREM2/HGF/CD83/CD28/TUSC2/XCL1/TNFSF4/HMGB1/NOD2/CD40LG	10
BP	GO:0033762	response to glucagon	10/2619	36/18670	0.02302	0.1031	0.07734	QDPR/PRKAR2A/CCNA2/CYC1/ASS1/ADCY1/CPS1/ADCY2/CREB1/CRY1	10
BP	GO:0045841	negative regulation of mitotic metaphase/anaphase transition	10/2619	36/18670	0.02302	0.1031	0.07734	ATM/TPR/BUB1B/LCMT1/NDC80/CCNB1/CDC20/AURKB/CENPF/FBXO5	10
BP	GO:0046627	negative regulation of insulin receptor signaling pathway	10/2619	36/18670	0.02302	0.1031	0.07734	PTPRE/ENPP1/PRKCB/PID1/SOCS1/PTPN2/GRB10/PRKCQ/PRKAA1/CISH	10
BP	GO:0097242	amyloid-beta clearance	10/2619	36/18670	0.02302	0.1031	0.07734	TREM2/CLU/LRPAP1/APOE/INSR/IDE/ROCK1/IFNG/HDAC1/RAB11B	10
BP	GO:2000516	positive regulation of CD4-positive, alpha-beta T cell activation	10/2619	36/18670	0.02302	0.1031	0.07734	RIPK2/MALT1/IL4R/CD83/SOCS1/CD81/IFNG/XCL1/TNFSF4/PRKCQ	10
BP	GO:2001171	positive regulation of ATP biosynthetic process	10/2619	36/18670	0.02302	0.1031	0.07734	TREM2/PID1/PINK1/INSR/PFKFB3/TAZ/IFNG/IGF1/HIF1A/PRKAA1	10
BP	GO:0048568	embryonic organ development	75/2619	428/18670	0.02323	0.104	0.078	ZIC1/SIX1/HOXA11/EFEMP1/NOTCH1/FOLR1/CEBPA/SOX9/MAPK3/ERCC1/NIPBL/SMAD3/FOXC1/TCF7/TUBB2B/RBP4/EGFR/IFT52/ADA/MDFI/KIT/BMP4/C2CD3/WNT11/HOXB6/LEF1/MED1/FZD3/BBS4/NAGLU/PRKRA/OSR2/MICAL2/ARID1A/HOXA4/FOXF1/ZFPM2/SIX2/KDR/CDKN1C/RBPJ/EN1/PDGFB/PRDM1/VEGFA/HOXB5/IFT140/ALDH1A3/IRX5/TMED2/HOXD9/SOD1/PLCD1/PHACTR4/HIF1A/HOXA5/ERCC2/SETD2/BPTF/SIX3/ID2/ID3/GGNBP2/CEP290/HOXC11/FZD6/SH2B3/CXCL8/HOXA7/CEBPB/SMO/TH/TWIST1/FZD2/SATB2	75
BP	GO:0060760	positive regulation of response to cytokine stimulus	14/2619	57/18670	0.02348	0.1047	0.07852	TREM2/RIPK2/AGPAT1/TBK1/ADAM17/CASP4/MED1/IRF3/CXCR4/TXK/AXL/MMP12/HIF1A/TRIM32	14
BP	GO:1900408	negative regulation of cellular response to oxidative stress	14/2619	57/18670	0.02348	0.1047	0.07852	SLC7A11/HGF/NME5/PINK1/MAPK7/NOL3/GPX1/HSPB1/TRAP1/HIF1A/VNN1/PYCR1/ATF4/PSAP	14
BP	GO:0007076	mitotic chromosome condensation	6/2619	17/18670	0.02352	0.1047	0.07852	NIPBL/NUSAP1/NCAPH/NCAPG/SMC4/AKAP8	6
BP	GO:0015919	peroxisomal membrane transport	6/2619	17/18670	0.02352	0.1047	0.07852	PEX10/PEX19/PEX7/PEX2/PEX12/PEX14	6
BP	GO:0017085	response to insecticide	6/2619	17/18670	0.02352	0.1047	0.07852	SCN1B/DAXX/CCNB1/HNRNPA1/CPOX/TH	6
BP	GO:0018904	ether metabolic process	6/2619	17/18670	0.02352	0.1047	0.07852	EPHX1/EPHX2/DHRS7B/PEX7/TXN2/AGPS	6
BP	GO:1903975	regulation of glial cell migration	6/2619	17/18670	0.02352	0.1047	0.07852	TREM2/GPR183/CX3CR1/CERS2/P2RX4/CCR2	6
BP	GO:1904355	positive regulation of telomere capping	6/2619	17/18670	0.02352	0.1047	0.07852	MAPK3/TNKS2/AURKB/PRKCQ/NABP2/HNRNPD	6
BP	GO:0007173	epidermal growth factor receptor signaling pathway	25/2619	119/18670	0.02361	0.105	0.07876	EFEMP1/SOX9/REPS2/FBXW7/BTC/SOS1/ADAM17/EGFR/EGF/NCK2/GPER1/PTPN2/CHMP6/CBLB/ARHGEF7/AGT/HBEGF/EREG/PLCE1/RHBDF2/HIP1R/PTK2B/NUP62/PIK3CA/NCF1	25
BP	GO:0008585	female gonad development	21/2619	96/18670	0.02379	0.1055	0.07913	SFRP1/NUPR1/FOXC1/ATM/INSR/KIT/PLEKHA1/ARRB1/ZFPM2/NOS3/ANG/BRCA2/EREG/VEGFA/UBB/SOD1/GDF9/SGPL1/INHBB/CEBPB/HSPA5	21
BP	GO:0032755	positive regulation of interleukin-6 production	21/2619	96/18670	0.02379	0.1055	0.07913	RIPK2/LILRB2/LILRA2/ARHGEF2/IL1RL2/F2R/IL6/EREG/TYROBP/TNFSF4/HMGB1/NOD2/LPL/IL17RC/IL1RN/NOD1/IL6R/XBP1/MYD88/TLR8/TWIST1	21
BP	GO:1990823	response to leukemia inhibitory factor	21/2619	96/18670	0.02379	0.1055	0.07913	MTF2/JARID2/TFRC/PCOLCE/ADAM23/PIGA/KDM3A/PCOLCE2/PML/EED/SRM/SNX10/SPOCK2/SMARCA5/PADI2/PMM1/CREB1/XBP1/MPC1/NR5A2/SBNO2	21
BP	GO:1990830	cellular response to leukemia inhibitory factor	21/2619	96/18670	0.02379	0.1055	0.07913	MTF2/JARID2/TFRC/PCOLCE/ADAM23/PIGA/KDM3A/PCOLCE2/PML/EED/SRM/SNX10/SPOCK2/SMARCA5/PADI2/PMM1/CREB1/XBP1/MPC1/NR5A2/SBNO2	21
BP	GO:0051258	protein polymerization	52/2619	283/18670	0.02381	0.1055	0.07914	IQGAP2/ACTR3B/JAK2/STMN2/ARPC1A/TUBG2/SNCA/NDE1/MICALL2/TMOD1/CDC42EP3/ARL2/FGF13/FCHSD2/PFN2/BAIAP2/NCK2/PINK1/ACTR3/PSTPIP2/CAPZA1/BIN1/MAPRE3/MAP7D3/BBS4/DRG1/GPX4/CDH5/CHMP2A/ANG/TMOD2/CLASP1/FHOD3/MAGEL2/TUBGCP5/MSRB2/SCIN/CCR7/AP1AR/TMSB10/TTC17/ARPC5L/AKAP9/RANGRF/CTTN/HIP1R/CYFIP1/PTK2B/ARFGEF1/ACTR2/TUBGCP2/FBXO5	52
BP	GO:0043254	regulation of protein complex assembly	81/2619	467/18670	0.02383	0.1056	0.07917	AIM2/IQGAP2/ACTR3B/SETX/LCP1/STMN2/ARPC1A/CXCL13/ERCC1/SNCA/CLU/TMOD1/ATR/CDC42EP3/ARL2/ATM/ATF7IP/FCHSD2/PFN2/BAIAP2/CTNNBIP1/ASAP1/NCK2/PINK1/RPA1/ACTR3/APOE/GSK3B/BIRC2/CAPZA1/BIN1/IDE/MAPRE3/ARHGEF2/LCMT1/RPA3/ZNF451/PSMC2/BBS4/PTGER4/CRYAB/DRG1/CDH5/VPS16/IFNG/INSM1/PSMC3/RASIP1/TMOD2/CLASP1/FHOD3/MAGEL2/TAF7/VEGFA/SCIN/HMGB1/HJURP/CCR7/AP1AR/DDB2/TMSB10/PEX14/ARPC5L/ERCC2/AKAP9/PRKAA1/RANGRF/CTTN/RAF1/CREB1/HIP1R/CYFIP1/EP300/RIOK3/GTF2H3/PTK2B/STYXL1/NAPA/ARFGEF1/ACTR2/TWIST1	81
BP	GO:0002292	T cell differentiation involved in immune response	16/2619	68/18670	0.0239	0.1057	0.07927	RIPK2/MALT1/RORA/SEMA4A/IL4R/GPR183/LEF1/PTGER4/RC3H2/RELB/IFNG/LY9/IL6/TNFSF4/HMGB1/BATF	16
BP	GO:0031343	positive regulation of cell killing	16/2619	68/18670	0.0239	0.1057	0.07927	HLA-C/RASGRP1/HLA-F/HLA-G/MICB/HLA-A/PTPRC/BAD/HLA-B/HLA-E/PRF1/CRTAM/IFNG/TYROBP/XCL1/ULBP2	16
BP	GO:0071103	DNA conformation change	59/2619	327/18670	0.02396	0.1059	0.07942	CETN2/SRPK1/SETX/NAP1L3/SMCHD1/SOX9/CHD1/CHD8/HNRNPA2B1/NBN/NIPBL/RECQL/DNA2/NAP1L2/RPA1/SART3/SET/TPR/DDX11/NUSAP1/GPER1/NCAPH/GINS1/ASCC3/BANF1/DAXX/HMGB3/CCNB1/NCAPG/NASP/TOP1/ATRX/UBB/HMGB1/HJURP/RAD50/TOP2A/DDB2/CENPT/CHD3/RUVBL2/KAT6A/SMC4/WRN/DDX1/SMARCA5/AKAP8/ERCC2/TSPYL1/DFFB/CDK1/CENPC/MNAT1/TSPYL5/GTF2H3/UBN1/RFC2/HMGA1/HMGA2	59
BP	GO:0008154	actin polymerization or depolymerization	40/2619	209/18670	0.02405	0.1062	0.07967	MICAL1/IQGAP2/ACTR3B/JAK2/ARPC1A/MICALL2/TMOD1/CDC42EP3/FCHSD2/PFN2/BAIAP2/NCK2/ACTR3/PSTPIP2/CAPZA1/BIN1/BBS4/MICAL2/WIPF1/ANG/TMOD2/GHSR/FHOD3/MAGEL2/MSRB2/SCIN/ARHGAP35/CCR7/AP1AR/TMSB10/TTC17/ABI1/ARPC5L/CTTN/HIP1R/CYFIP1/LIMA1/PTK2B/ARFGEF1/ACTR2	40
BP	GO:0055076	transition metal ion homeostasis	27/2619	131/18670	0.02426	0.107	0.08025	SLC22A17/TFRC/SKP1/SRI/ATP6V0D1/NEO1/PRNP/BDH2/IREB2/SCO2/HFE/NDFIP1/EPB42/LCK/CYBRD1/FTL/SLC39A8/MYC/SLC31A2/SLC11A1/PRND/CP/SLC39A14/SOD1/HIF1A/CUTC/NEDD8	27
BP	GO:0098754	detoxification	27/2619	131/18670	0.02426	0.107	0.08025	GCH1/LTC4S/PTGS1/AKR1B10/FBLN5/ALOX5AP/APOM/AKR7A3/NQO1/APOE/GPX3/PRDX6/MGST3/GSTZ1/PXDN/GPX1/ESD/CAT/GPX4/NOS3/IPCEF1/GSTM3/SOD1/HBB/PRDX2/SESN1/TXNRD2	27
BP	GO:2000379	positive regulation of reactive oxygen species metabolic process	22/2619	102/18670	0.02449	0.1079	0.08094	JAK2/SNCA/CLU/SMAD3/DDAH1/RAB27A/PID1/EGFR/INSR/DDAH2/IFNG/AGT/ASS1/TSPO/AKR1C3/TYROBP/PDGFB/P2RX4/SOD1/HBB/CDKN1A/PTK2B	22
BP	GO:0030879	mammary gland development	29/2619	143/18670	0.02466	0.1085	0.08139	AR/JAK2/SOX9/IGFBP5/EGF/NOTCH4/TNFRSF11A/BMP4/LEF1/MED1/GPX1/FOXF1/LRP5/BRCA2/PML/DEAF1/VEGFA/ARHGAP35/HOXD9/HIF1A/HOXA5/CREB1/ID2/STAT5A/OAS2/ERBB4/XBP1/CEBPB/SMO	29
BP	GO:0044344	cellular response to fibroblast growth factor stimulus	29/2619	143/18670	0.02466	0.1085	0.08139	SFRP1/SETX/CCL5/PRKD2/MAPK3/CXCL13/SNCA/POLR2J/POLR2I/POLR2L/POLR2E/POLR2F/FGF20/FIBP/SHOC2/POLR2C/CD44/POSTN/TIA1/FGF18/SHCBP1/POLR2G/CPS1/GALNT3/HNRNPA1/ZFP36L2/NCBP2/CXCL8/FGF5	29
BP	GO:0016447	somatic recombination of immunoglobulin gene segments	13/2619	52/18670	0.02474	0.1087	0.08153	PARP3/TFRC/IL27RA/ERCC1/NBN/PTPRC/THOC1/CD28/CD40/TNFSF4/BATF/TCF3/CD40LG	13
BP	GO:0032653	regulation of interleukin-10 production	13/2619	52/18670	0.02474	0.1087	0.08153	TREM2/HGF/TNFRSF21/IDO1/CD83/CD28/TUSC2/TYROBP/XCL1/TNFSF4/HMGB1/NOD2/CD40LG	13
BP	GO:0009267	cellular response to starvation	30/2619	149/18670	0.02478	0.1088	0.08161	SFRP1/SIK1/MAP3K5/DAP/MAPK3/GABARAPL1/FAS/GABARAPL2/SLC38A2/COMT/ATF3/RRAGA/HFE/PIK3C2B/TBL2/AKR1C3/HNRNPA1/WRN/PRKAA1/IFI16/RRAGD/CDKN1A/XBP1/SESN1/INHBB/ATF4/HSPA5/GABARAP/ASNS/CLEC16A	30
BP	GO:0048588	developmental cell growth	44/2619	234/18670	0.02479	0.1088	0.08161	SOX9/SEMA4D/MACF1/SEMA4A/SEMA3A/SPG11/FGF13/ITSN2/NDN/APOE/GSK3B/SEMA4C/EFNA5/CYFIP2/CXCR4/SYT17/AUTS2/POSTN/RGS4/AGT/SEMA3F/CTDP1/IGF1/RND2/SORBS2/VEGFA/PIN1/SEMA3E/USP9X/CTTN/GOLGA4/GDF9/TRPV2/AKAP13/GAL/CDKL5/PLXNA1/SYT1/CYFIP1/DSCAM/CPNE6/BCL11A/BDNF/NEDD4L	44
BP	GO:0010977	negative regulation of neuron projection development	31/2619	155/18670	0.02485	0.1089	0.08167	STMN2/GAK/SEMA4D/SEMA4A/SPOCK1/CD38/SEMA3A/FGF13/ASAP1/ZNF365/APOE/GSK3B/SEMA4C/DGUOK/PMP22/YWHAH/CERS2/PLK2/KLK8/SEMA3F/MAP4K4/TLX2/ITM2C/EPHA4/NR2F1/SEMA3E/PPP3CA/CIB1/NGFR/BCL11A/LRIG2	31
BP	GO:0060968	regulation of gene silencing	31/2619	155/18670	0.02485	0.1089	0.08167	ADAR/DNMT1/POLR2J/POLR2I/NUP160/POLR2L/ATF7IP/NUP153/EGFR/POLR2E/POLR2F/PUM2/ATAD2B/TPR/BMP4/NUP50/PPARG/POLR2C/SEC13/RANBP2/POLR2G/NUP210/DND1/PPP3CA/NCOR1/NUP43/NDC1/ATAD2/NUP98/HMGA1/NUP62	31
BP	GO:0010970	transport along microtubule	32/2619	161/18670	0.02488	0.1089	0.08167	MREG/IFT46/RASGRP1/ARL3/NDE1/UCHL1/RPGR/SYNE2/SPG11/IFT52/DYNLRB1/BLOC1S1/TRAK1/HSPB1/KIF5C/PCM1/DYNC1I1/VAMP7/KIF4A/TNPO1/CLUAP1/DYNC1H1/IFT140/UBB/SFPQ/PEX14/SOD1/SPAST/HIF1A/IFT22/TRIM58/DYNC2LI1	32
BP	GO:0099111	microtubule-based transport	32/2619	161/18670	0.02488	0.1089	0.08167	MREG/IFT46/RASGRP1/ARL3/NDE1/UCHL1/RPGR/SYNE2/SPG11/IFT52/DYNLRB1/BLOC1S1/TRAK1/HSPB1/KIF5C/PCM1/DYNC1I1/VAMP7/KIF4A/TNPO1/CLUAP1/DYNC1H1/IFT140/UBB/SFPQ/PEX14/SOD1/SPAST/HIF1A/IFT22/TRIM58/DYNC2LI1	32
BP	GO:0046916	cellular transition metal ion homeostasis	23/2619	108/18670	0.02508	0.1097	0.08226	SLC22A17/TFRC/SKP1/SRI/ATP6V0D1/PRNP/IREB2/SCO2/HFE/NDFIP1/LCK/CYBRD1/FTL/SLC39A8/MYC/SLC31A2/SLC11A1/PRND/CP/SLC39A14/SOD1/HIF1A/NEDD8	23
BP	GO:0086001	cardiac muscle cell action potential	17/2619	74/18670	0.02537	0.1109	0.08315	SCN1B/ATP1B1/SNTA1/KCNQ1/FGF13/BIN1/KCNJ2/ANK3/CACNB2/KCNJ8/KCNN2/AKAP9/RANGRF/CACNA1D/CXADR/FLNA/NEDD4L	17
BP	GO:2000027	regulation of animal organ morphogenesis	47/2619	253/18670	0.02552	0.1114	0.08358	TNFAIP3/SIX1/HOXA11/SFRP1/PTN/NOTCH1/DIO3/AR/STAT1/TNFRSF11B/SOX9/FBXW7/CFLAR/FOXC1/PSMB9/HGF/PIM1/AP2M1/RXRA/BMP4/WNT11/PLEKHA4/MAGI2/MED1/PSMC2/CHAD/FZD3/PSMB6/AGT/SIX2/TBX5/PSMC3/MYC/RBPJ/VEGFA/PSMD8/MAGED1/PSMB5/PSMD10/MMP20/HOXC11/FZD6/XBP1/FZD7/SMO/TWIST1/FZD2	47
BP	GO:0002699	positive regulation of immune effector process	41/2619	216/18670	0.02557	0.1116	0.08371	HLA-C/RASGRP1/TFRC/MAPK3/RIPK2/MALT1/HLA-F/HLA-G/MICB/HLA-A/IL4R/PTPRC/RBP4/PUM2/TNFRSF14/HLA-B/HLA-E/CD28/CRTAM/PHB/FGR/CD40/FOXF1/CD81/MZB1/IFNG/RAC2/VAMP7/IL6/XCL1/TNFSF4/NOD2/ULBP2/DDX1/DDX60/DDX21/BCL10/XBP1/IL13RA2/CCR2/FBXO38	41
BP	GO:1903362	regulation of cellular protein catabolic process	46/2619	247/18670	0.02585	0.1121	0.08412	TNFAIP3/NUPR1/CEBPA/NELL1/TREM2/FBXW7/CLU/LAMP3/HERPUD1/GABARAPL2/ATRAID/CBFA2T3/UBE2J1/EGF/PINK1/APOE/GSK3B/CHFR/HFE/PSMC2/GPX1/FHIT/CD81/PLK2/TRIB1/DET1/PML/EPHA4/CSNK1A1/RNF19B/UBB/UBQLN4/GLMN/WDR91/CSNK1E/EDEM1/NFE2L1/PSMD10/TMF1/OGT/RYBP/RNF14/N4BP1/PTK2B/CLEC16A/USP14	46
BP	GO:0002204	somatic recombination of immunoglobulin genes involved in immune response	12/2619	47/18670	0.02591	0.1121	0.08412	PARP3/TFRC/IL27RA/ERCC1/NBN/PTPRC/THOC1/CD28/CD40/TNFSF4/BATF/CD40LG	12
BP	GO:0002208	somatic diversification of immunoglobulins involved in immune response	12/2619	47/18670	0.02591	0.1121	0.08412	PARP3/TFRC/IL27RA/ERCC1/NBN/PTPRC/THOC1/CD28/CD40/TNFSF4/BATF/CD40LG	12
BP	GO:0008206	bile acid metabolic process	12/2619	47/18670	0.02591	0.1121	0.08412	CH25H/OSBPL3/ACOX2/ATP8B1/SLC27A5/KIT/CYP7B1/SCP2/ACOT8/AKR1C4/NPC1/NR5A2	12
BP	GO:0021695	cerebellar cortex development	12/2619	47/18670	0.02591	0.1121	0.08412	RORA/EZH2/B4GALT2/AGTPBP1/ZNF365/HERC1/NAGLU/UQCRQ/SEZ6L/SMO/HSPA5/MYH10	12
BP	GO:0042461	photoreceptor cell development	12/2619	47/18670	0.02591	0.1121	0.08412	DIO3/ARL3/NTRK2/BBS4/NAGLU/PRKCI/PRDM1/VEGFA/IFT140/CEP290/NRL/TH	12
BP	GO:0045023	G0 to G1 transition	12/2619	47/18670	0.02591	0.1121	0.08412	CDC7/SUZ12/HLA-G/CHEK1/EZH2/RRM2/MED1/APAF1/MGA/EED/RYBP/RING1	12
BP	GO:0045190	isotype switching	12/2619	47/18670	0.02591	0.1121	0.08412	PARP3/TFRC/IL27RA/ERCC1/NBN/PTPRC/THOC1/CD28/CD40/TNFSF4/BATF/CD40LG	12
BP	GO:1901659	glycosyl compound biosynthetic process	12/2619	47/18670	0.02591	0.1121	0.08412	NME4/TK2/NME7/IMPDH2/NME5/ADK/ADA/NME3/TYMP/GUK1/CTPS1/NT5E	12
BP	GO:0022612	gland morphogenesis	25/2619	120/18670	0.02598	0.1121	0.08412	TNFAIP3/SFRP1/PTN/NOTCH1/AR/SOX9/IGFBP5/FBXW7/CFLAR/HGF/SEMA3A/EGFR/RXRA/BMP4/CYP7B1/MED1/LAMA5/ID4/LRP5/PML/PLXND1/PLXNA1/XBP1/RPS6KA1/CEBPB	25
BP	GO:1903522	regulation of blood circulation	54/2619	297/18670	0.02601	0.1121	0.08412	ADORA3/GCH1/SCN1B/ATP1B1/SNTA1/JAK2/FXYD1/ATP2A3/SRI/KCNQ1/CELF2/CD38/KCNK15/SEMA3A/FXYD6/FGF13/EGFR/STC1/ADA/BIN1/EHD3/KCNK3/ASPH/KCNJ2/MYL3/F2R/ITPR2/NPR2/RGS4/ATP2B2/AGT/NOS3/S100A1/HBEGF/P2RX4/MYL4/IRX5/CACNB2/KCNN2/GAA/AKAP9/RANGRF/TAC1/ATP2B4/CACNA1D/KCND1/CXADR/CACNA2D3/FLNA/SLC1A1/KCNMB2/ATP2B1/TH/CORIN	54
BP	GO:1902905	positive regulation of supramolecular fiber organization	39/2619	204/18670	0.02603	0.1121	0.08412	SFRP1/IQGAP2/ACTR3B/STMN2/ARPC1A/CLU/SMAD3/CDC42EP3/ARL2/FCHSD2/PFN2/BAIAP2/NCK2/ACTR3/APOE/LIMCH1/BIN1/WNT11/GPX1/DRG1/PPM1E/CLASP1/MAGEL2/MYOC/SCIN/CCR7/AP1AR/SPAST/KATNB1/ARPC5L/AKAP9/NF2/TAC1/CTTN/HIP1R/CYFIP1/FLNA/PTK2B/ACTR2	39
BP	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity	5/2619	13/18670	0.0262	0.1121	0.08412	ANGPT1/EGF/EFNA5/ADRB2/CHRNA3	5
BP	GO:0007494	midgut development	5/2619	13/18670	0.0262	0.1121	0.08412	EGFR/FOXF1/ASS1/CPS1/SMO	5
BP	GO:0014745	negative regulation of muscle adaptation	5/2619	13/18670	0.0262	0.1121	0.08412	IGFBP5/SMAD3/NOL3/NOS3/ATP2B4	5
BP	GO:0014842	regulation of skeletal muscle satellite cell proliferation	5/2619	13/18670	0.0262	0.1121	0.08412	SIX1/JAK2/ANGPT1/CFLAR/PAXBP1	5
BP	GO:0016558	protein import into peroxisome matrix	5/2619	13/18670	0.0262	0.1121	0.08412	PEX10/PEX7/PEX2/PEX12/PEX14	5
BP	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway	5/2619	13/18670	0.0262	0.1121	0.08412	TNFAIP3/LILRA2/CARD8/TRIB1/PRDX2	5
BP	GO:0032823	regulation of natural killer cell differentiation	5/2619	13/18670	0.0262	0.1121	0.08412	RASGRP1/IL15/TOX/AXL/PRDM1	5
BP	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein	5/2619	13/18670	0.0262	0.1121	0.08412	SOCS1/PTPN2/NF2/GGNBP2/SH2B3	5
BP	GO:0043970	histone H3-K9 acetylation	5/2619	13/18670	0.0262	0.1121	0.08412	CHEK1/NAP1L2/ZNF451/KAT2B/PIWIL2	5
BP	GO:0045086	positive regulation of interleukin-2 biosynthetic process	5/2619	13/18670	0.0262	0.1121	0.08412	PTPRC/CD28/CD3E/GLMN/PRKCQ	5
BP	GO:0047484	regulation of response to osmotic stress	5/2619	13/18670	0.0262	0.1121	0.08412	BAD/ARHGEF2/MICU1/ABCB1/LETM1	5
BP	GO:0060576	intestinal epithelial cell development	5/2619	13/18670	0.0262	0.1121	0.08412	PRDM1/HIF1A/HOXA5/TYMS/CDKN1A	5
BP	GO:0061029	eyelid development in camera-type eye	5/2619	13/18670	0.0262	0.1121	0.08412	SOS1/EGFR/OSR2/HDAC1/TWIST1	5
BP	GO:0061042	vascular wound healing	5/2619	13/18670	0.0262	0.1121	0.08412	TNFAIP3/NDNF/SERPINE1/CXCR4/XBP1	5
BP	GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	5/2619	13/18670	0.0262	0.1121	0.08412	TNFAIP3/NFKBIA/RIPK2/PTPN22/NOD2	5
BP	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading	5/2619	13/18670	0.0262	0.1121	0.08412	GBP1/EFNA5/POSTN/AP1AR/FBLN1	5
BP	GO:0007626	locomotory behavior	38/2619	198/18670	0.02624	0.1122	0.08418	HPGDS/ZIC1/GPR88/SLC18A2/SNCA/ANKH/TMOD1/UCHL1/SPG11/B4GALT2/IDO1/APOE/PENK/NAGLU/ADAM22/CLN6/C12orf10/CHRNA3/MCOLN3/GHSR/EGR1/EN1/NPY1R/EPHA4/NOVA1/ALDH1A3/HOXD9/NCOR1/SOD1/GAA/APH1B/ID2/NPC1/DSCAM/SEZ6L/PSAP/PBX3/TH	38
BP	GO:0060070	canonical Wnt signaling pathway	60/2619	335/18670	0.02631	0.1125	0.08436	SFRP1/NOTCH1/FOLR1/WNT5B/GPC5/CDH2/SOX9/IGFBP2/CHD8/SMAD3/ASPM/TNKS2/PSMB9/TCF7/SDC1/NLE1/EGFR/EGF/ZBED2/APOE/GSK3B/IGFBP4/WNT11/PLEKHA4/LEF1/PSMC2/USP47/FZD3/USP34/NFKB1/PSMB6/WLS/LRP5/PSMC3/EGR1/RBPJ/CSNK1A1/DKK4/PIN1/USP8/PSMD8/LGR5/FERMT1/PSMB5/FRAT1/CSNK1E/RUVBL2/PFDN5/PSMD10/TLE3/HDAC1/CYLD/TCF7L2/TLE2/FZD6/CAPRIN2/UBR5/FZD7/DDIT3/FZD2	60
BP	GO:1901136	carbohydrate derivative catabolic process	37/2619	192/18670	0.02642	0.1125	0.08436	FUCA1/GPC5/GUSB/GNPDA1/SDC1/PDE1A/ENTPD4/TDG/ADA/APOBEC3C/DPYS/SAMHD1/FBXO17/HMMR/TYMP/NUDT9/NAGLU/CD44/PNP/HEXA/NUDT11/ACAT1/NGLY1/MAN1B1/GM2A/APOBEC3B/AHCY/MMP12/EDEM1/NEU1/NT5E/VCAN/SGSH/KERA/AMPD3/PSAP/ARSB	37
BP	GO:0006312	mitotic recombination	7/2619	22/18670	0.02643	0.1125	0.08436	SMC6/ERCC1/SMC5/BRCA2/RAD51C/RAD50/ERCC2	7
BP	GO:0006783	heme biosynthetic process	7/2619	22/18670	0.02643	0.1125	0.08436	FECH/IREB2/UROD/UROS/TSPO/NFE2L1/CPOX	7
BP	GO:0046599	regulation of centriole replication	7/2619	22/18670	0.02643	0.1125	0.08436	MDM1/PLK2/CHMP2A/ALMS1/KAT2B/SPICE1/NUP62	7
BP	GO:0060547	negative regulation of necrotic cell death	7/2619	22/18670	0.02643	0.1125	0.08436	BIRC3/SLC25A4/CFLAR/BIRC2/NOL3/ARHGEF2/PELI1	7
BP	GO:0090312	positive regulation of protein deacetylation	7/2619	22/18670	0.02643	0.1125	0.08436	PRKD2/NIPBL/PINK1/ING2/IFNG/VEGFA/AKAP8	7
BP	GO:0048709	oligodendrocyte differentiation	21/2619	97/18670	0.02648	0.1125	0.08436	PTN/NOTCH1/TNFRSF1B/SOX9/CLU/CDKN2C/TNFRSF21/ZNF365/NTRK2/PRMT5/ERBB2/PPARG/CXCR4/ID4/ERCC2/HDAC1/FA2H/OLIG2/ID2/PLP1/TENM4	21
BP	GO:0120162	positive regulation of cold-induced thermogenesis	21/2619	97/18670	0.02648	0.1125	0.08436	JAK2/PEMT/IL4R/PRKAB1/KDM3A/CXCR4/ADRB2/HADH/GRB10/GATM/HCRT/VEGFA/DYNC1H1/DIO2/ALMS1/OGT/TRPV2/CCR2/CEBPB/FH/LPIN1	21
BP	GO:0006469	negative regulation of protein kinase activity	44/2619	235/18670	0.02649	0.1125	0.08436	TNFAIP3/DUSP5/SFRP1/CEBPA/IRAK3/ADAR/PRKAR2A/DUSP6/UCHL1/PTPRC/CDKN2C/DEPTOR/APOE/CHORDC1/SOCS1/LAX1/BMP4/DNAJA1/PTPN22/PTPN2/CHMP6/FGFR1OP/HSPB1/CBLB/IFNG/RGS4/TRIB1/PPM1E/LRP5/RASIP1/CDKN1C/TAF7/DUSP2/DNAJC3/NF2/TAOK3/CIB1/PAK2/GGNBP2/KAT2B/CDKN1A/SH2B3/MVP/NUP62	44
BP	GO:0060560	developmental growth involved in morphogenesis	44/2619	235/18670	0.02649	0.1125	0.08436	SIX1/SFRP1/NOTCH1/SOX9/SEMA4D/MACF1/SEMA4A/SEMA3A/SPG11/FGF13/ITSN2/NDN/APOE/GSK3B/BMP4/SEMA4C/EFNA5/WNT11/MAGI2/MED1/CYFIP2/CXCR4/SYT17/S1PR1/AUTS2/POSTN/SEMA3F/RND2/VEGFA/SEMA3E/USP9X/CTTN/GOLGA4/TRPV2/GAL/CDKL5/PLXNA1/SYT1/CYFIP1/DSCAM/CPNE6/BCL11A/BDNF/NEDD4L	44
BP	GO:0034767	positive regulation of ion transmembrane transport	31/2619	156/18670	0.02698	0.1145	0.08586	CXCL9/CXCL10/ATP1B1/TREM2/FXYD1/PLCG2/SNCA/SRI/KCNQ1/CXCL11/FGF14/PINK1/EHD3/KCNJ2/ANK3/GPER1/F2R/ADRB2/IFNG/AGT/S100A1/XCL1/CD19/CALCR/CACNB2/ABCB1/AKAP9/GAL/HSPA2/FLNA/CCR2	31
BP	GO:0035306	positive regulation of dephosphorylation	14/2619	58/18670	0.02708	0.1148	0.08614	JAK2/SMAD3/CAMTA1/LILRB2/PTPRC/MTMR9/PINK1/MAGI2/PPP1R16B/CDH5/PPP1R12A/IFNG/PIN1/ANKLE2	14
BP	GO:0042698	ovulation cycle	16/2619	69/18670	0.02719	0.1152	0.08642	PTN/GABRB1/EGFR/PLEKHA1/ARRB1/NOS3/EGR1/AXL/EREG/TIMP4/HAS2/GDF9/TYRO3/SGPL1/SERPINF1/HSPA5	16
BP	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion	10/2619	37/18670	0.0277	0.1166	0.08743	ERCC1/POLD2/RPA1/RPA3/POLD4/UBB/DDB2/ERCC2/GTF2H3/RFC2	10
BP	GO:0006921	cellular component disassembly involved in execution phase of apoptosis	10/2619	37/18670	0.0277	0.1166	0.08743	DNASE1L3/GPER1/APAF1/IL6/DNASE2/HMGB1/TOP2A/KPNB1/DFFB/KPNA1	10
BP	GO:0060236	regulation of mitotic spindle organization	10/2619	37/18670	0.0277	0.1166	0.08743	PARP3/TPX2/TPR/DRG1/CHMP2A/DYNC1H1/SMC1A/CHMP1B/TACC3/NUP62	10
BP	GO:1902100	negative regulation of metaphase/anaphase transition of cell cycle	10/2619	37/18670	0.0277	0.1166	0.08743	ATM/TPR/BUB1B/LCMT1/NDC80/CCNB1/CDC20/AURKB/CENPF/FBXO5	10
BP	GO:2000142	regulation of DNA-templated transcription, initiation	10/2619	37/18670	0.0277	0.1166	0.08743	SETX/ATF7IP/CTNNBIP1/ZNF451/PSMC2/PSMC3/TAF7/HMGB1/CREB1/TWIST1	10
BP	GO:2000403	positive regulation of lymphocyte migration	10/2619	37/18670	0.0277	0.1166	0.08743	CXCL10/CCL5/CXCL13/ADAM17/TNFRSF14/XCL1/TNFSF14/CCL7/PTK2B/CCR2	10
BP	GO:0032760	positive regulation of tumor necrosis factor production	19/2619	86/18670	0.02771	0.1166	0.08743	JAK2/RASGRP1/RIPK2/CLU/PTPRC/LILRA2/HLA-E/ARHGEF2/HSPB1/IFNG/TYROBP/HMGB1/NOD2/MAPKAPK2/LPL/CD2/NOD1/CCR2/TWIST1	19
BP	GO:0042058	regulation of epidermal growth factor receptor signaling pathway	19/2619	86/18670	0.02771	0.1166	0.08743	FBXW7/BTC/SOS1/ADAM17/EGFR/EGF/NCK2/GPER1/PTPN2/CHMP6/CBLB/ARHGEF7/AGT/HBEGF/EREG/RHBDF2/HIP1R/NUP62/NCF1	19
BP	GO:0060291	long-term synaptic potentiation	19/2619	86/18670	0.02771	0.1166	0.08743	PTN/LGMN/SNCA/LILRB2/PRNP/CX3CR1/NTRK2/APOE/GSK3B/PLK2/ADCY1/TYROBP/EPHA4/VAMP2/NRGN/CALB2/CREB1/PTK2B/STAU1	19
BP	GO:0002825	regulation of T-helper 1 type immune response	8/2619	27/18670	0.02775	0.1166	0.08743	IL27RA/RIPK2/IL4R/XCL1/SLC11A1/TNFSF4/IL6R/CCR2	8
BP	GO:0007176	regulation of epidermal growth factor-activated receptor activity	8/2619	27/18670	0.02775	0.1166	0.08743	FBXW7/ADAM17/EGF/NCK2/CHMP6/CBLB/EREG/NCF1	8
BP	GO:0035902	response to immobilization stress	8/2619	27/18670	0.02775	0.1166	0.08743	ERCC1/GOT1/PPARG/GAL/HNMT/PTK2B/ACTR2/TH	8
BP	GO:0071514	genetic imprinting	8/2619	27/18670	0.02775	0.1166	0.08743	DIRAS3/KCNQ1/ARID4B/NDN/CDKN1C/EED/ARID4A/PIK3CA	8
BP	GO:0009100	glycoprotein metabolic process	73/2619	419/18670	0.02796	0.1174	0.08803	MGAT4C/NDNF/GAL3ST4/GALNT11/UST/GALNT10/SDF2/IL15/EOGT/TNIP1/MPI/B4GALT2/UBE2J1/EXT2/NECAB3/GNPTAB/TMEM258/B3GALNT1/FUT1/DPM3/TRAK1/FBXO17/RFNG/GCNT3/DPY19L2P2/MAN2B2/DPAGT1/HEXA/ST3GAL2/CHST15/POFUT1/EXTL2/IGF1/DAD1/MAN1C1/NGLY1/B4GALT7/TMEM59/MAN1B1/HBEGF/ITM2C/MMP12/GALNT3/DHDDS/FUT8/CCR7/EDEM1/DDOST/ALG6/HIF1A/SPOCK2/OGT/MUC5AC/ERP44/PMM1/TCF7L2/ACOT8/VCAN/GOLPH3/ABO/ST8SIA2/ASGR1/FUT4/NPC1/C1GALT1C1/SGSH/CHST12/ARFGEF1/SEL1L/LMF1/ARSB/VEGFB/B4GALT3	73
BP	GO:0008608	attachment of spindle microtubules to kinetochore	9/2619	32/18670	0.02805	0.1175	0.08814	ECT2/RACGAP1/SPAG5/NDC80/CENPE/CCNB1/MIS12/AURKB/CENPC	9
BP	GO:0090504	epiboly	9/2619	32/18670	0.02805	0.1175	0.08814	ADAM17/ITGA5/CD44/HBEGF/CLASP1/CD151/MMP12/ARHGAP35/FLNA	9
BP	GO:1901661	quinone metabolic process	9/2619	32/18670	0.02805	0.1175	0.08814	AKR1B1/AKR1B10/COQ6/AKR7A2/AKR1C3/CYP4F11/COQ9/COQ2/AKR1C4	9
BP	GO:0002440	production of molecular mediator of immune response	52/2619	286/18670	0.02847	0.1192	0.08939	IRAK3/PARP3/TNFRSF1B/TFRC/IL27RA/MAPK3/ERCC1/ANGPT1/TRIL/NBN/MALT1/HLA-F/HLA-G/IL7R/IL4R/PTPRC/ATM/RBP4/THOC1/TNFRSF14/HLA-E/KIT/HFE/IGLV1-44/LAX1/SAMHD1/CD96/CD28/DENND1B/CD40/GCNT3/TCIRG1/ELANE/CD81/MZB1/IL6/XCL1/SLC11A1/HLA-DQB1/PMS2P1/CUEDC2/TNFSF4/NOD2/BATF/DDX1/DDX21/TCF3/BCL10/XBP1/IL13RA2/CCR2/CD40LG	52
BP	GO:0050702	interleukin-1 beta secretion	13/2619	53/18670	0.0287	0.1198	0.08988	TNFAIP3/AIM2/RIPK2/LILRA2/NLRP1/CARD8/PML/HMGB1/CCR7/NOD2/LPL/GSDMD/TLR8	13
BP	GO:0050704	regulation of interleukin-1 secretion	13/2619	53/18670	0.0287	0.1198	0.08988	TNFAIP3/AIM2/RIPK2/LILRA2/NLRP1/CARD8/PML/HMGB1/CCR7/NOD2/LPL/GSDMD/TLR8	13
BP	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	13/2619	53/18670	0.0287	0.1198	0.08988	SFRP1/SEMA4D/PTPRC/NTF3/SOCS1/PTPN2/CHMP6/FGFR1OP/CBLB/NF2/GGNBP2/SH2B3/MVP	13
BP	GO:0070228	regulation of lymphocyte apoptotic process	13/2619	53/18670	0.0287	0.1198	0.08988	CCL5/IL7R/IDO1/ADA/BIRC7/BMP4/CD27/AURKB/PRKCQ/HIF1A/LGALS3/BCL10/CD3G	13
BP	GO:0001508	action potential	27/2619	133/18670	0.029	0.121	0.09078	SCN1B/ATP1B1/SNTA1/GPR88/SRI/KCNQ1/FGF13/NTRK2/BIN1/KCNJ2/ANK3/GPER1/YWHAH/P2RX4/CACNB2/KCNJ8/KCNN2/AKAP9/RANGRF/SCN9A/TAC1/CACNA1D/CXADR/FLNA/KCNMB2/NEDD4L/SCN3A	27
BP	GO:0016445	somatic diversification of immunoglobulins	15/2619	64/18670	0.02909	0.1211	0.09082	PARP3/TFRC/IL27RA/ERCC1/NBN/PTPRC/THOC1/SAMHD1/CD28/CD40/PMS2P1/TNFSF4/BATF/TCF3/CD40LG	15
BP	GO:0043550	regulation of lipid kinase activity	15/2619	64/18670	0.02909	0.1211	0.09082	SOCS6/SOCS1/KIT/FGR/CD81/DGKZ/PIK3R5/PDGFB/CD19/CCR7/NOD2/WDR91/PTK2B/CISH/RBL2	15
BP	GO:0045600	positive regulation of fat cell differentiation	15/2619	64/18670	0.02909	0.1211	0.09082	WIF1/SFRP1/CEBPA/WNT5B/AAMDC/PPARG/LMO3/LRP5/ASXL2/LPL/CREB1/ADIRF/ID2/XBP1/CEBPB	15
BP	GO:0046503	glycerolipid catabolic process	15/2619	64/18670	0.02909	0.1211	0.09082	PNPLA4/PNPLA6/LIPC/ABHD6/PLA2G15/APOE/PRDX6/GDE1/PLA2G4C/APOC1/CPS1/LPL/FABP7/FABP3/ABHD2	15
BP	GO:0031333	negative regulation of protein complex assembly	28/2619	139/18670	0.02915	0.1212	0.09092	STMN2/SNCA/CLU/TMOD1/PFN2/CTNNBIP1/GSK3B/BIRC2/CAPZA1/ARHGEF2/LCMT1/ZNF451/BBS4/PTGER4/CRYAB/CDH5/TMOD2/FHOD3/SCIN/HMGB1/TMSB10/PEX14/RAF1/HIP1R/EP300/RIOK3/STYXL1/ARFGEF1	28
BP	GO:0055088	lipid homeostasis	30/2619	151/18670	0.02926	0.1216	0.09121	CEBPA/LIPC/FBXW7/SEC24A/APOM/GOT1/RORA/EPHX2/ACOX2/MED13/APOE/CYP7B1/RCN3/PPARG/LRP5/NR1H2/ABCA2/COMMD9/NFE2L1/LPL/ACOX1/PRKAA1/ABHD8/XBP1/LIMA1/FABP3/NPC1/NR5A2/TMEM97/NR1D2	30
BP	GO:0010001	glial cell differentiation	41/2619	218/18670	0.0293	0.1217	0.0913	PTN/NOTCH1/TREM2/CDH2/TNFRSF1B/SOX9/LAMC3/MAPK3/CLU/CDKN2C/EGFR/TNFRSF21/ZNF365/NTRK2/PRMT5/BIN1/ERBB2/LEF1/NAB1/PPARG/CXCR4/ADAM22/ID4/IFNG/MXRA8/IL6/MYOC/EPHA4/NFE2L1/SOD1/ERCC2/HDAC1/FA2H/CDK1/OLIG2/ID2/KRAS/PLP1/FGF5/SMO/TENM4	41
BP	GO:0050848	regulation of calcium-mediated signaling	21/2619	98/18670	0.02939	0.122	0.09149	GBP1/PDK2/TREM2/SRI/TMEM100/CAMTA1/PRNP/ADA/GSK3B/MAPK7/DYRK2/ZAP70/CD3E/TRAT1/IGF1/P2RX4/HOMER3/ATP2B4/CIB1/FHL2/PTK2B	21
BP	GO:0051146	striated muscle cell differentiation	53/2619	293/18670	0.02967	0.1231	0.09232	SIX1/CXCL9/DYSF/SIK1/CXCL10/NOTCH1/PLEKHO1/CDH2/IGFBP5/TMOD1/UCHL1/IL4R/CFLAR/CBY1/SGCB/SDC1/EZH2/MYOM2/RXRA/BMP4/GPX1/NEBL/ARID1A/MAML1/CD81/RGS4/AGT/CHUK/CTDP1/IGF1/COMP/TBX5/CCNB1/TMOD2/FHOD3/RBPJ/SORBS2/SORT1/VEGFA/PIN1/CHRNB1/PPP3CA/TNFSF14/AKAP13/CDK1/CXADR/TRIM32/XBP1/KRAS/FZD7/SMO/MYH10/BDNF	53
BP	GO:0031334	positive regulation of protein complex assembly	49/2619	268/18670	0.02984	0.1237	0.09279	AIM2/IQGAP2/ACTR3B/SETX/LCP1/ARPC1A/CXCL13/ERCC1/CLU/ATR/CDC42EP3/ARL2/ATM/FCHSD2/PFN2/BAIAP2/ASAP1/NCK2/PINK1/RPA1/ACTR3/GSK3B/BIN1/IDE/RPA3/PSMC2/DRG1/CDH5/IFNG/PSMC3/RASIP1/CLASP1/MAGEL2/VEGFA/SCIN/CCR7/AP1AR/DDB2/ARPC5L/ERCC2/AKAP9/CTTN/CREB1/HIP1R/CYFIP1/GTF2H3/PTK2B/ACTR2/TWIST1	49
BP	GO:0032204	regulation of telomere maintenance	18/2619	81/18670	0.0299	0.1239	0.09291	MAPK3/ERCC1/HNRNPA2B1/NBN/ATR/TNKS2/ATM/DCP2/MYC/PML/ATRX/HMBOX1/AURKB/HNRNPA1/PRKCQ/RAD50/NABP2/HNRNPD	18
BP	GO:0006892	post-Golgi vesicle-mediated transport	22/2619	104/18670	0.03002	0.1242	0.09315	GAK/VPS13C/ARL3/MACF1/PREPL/EHD3/VTI1B/ANK3/BBS1/VAMP3/EXOC2/SEC16A/VAMP7/SORT1/MON2/AP1AR/OPTN/VAMP2/GOLGA4/GOLPH3/EXOC1/AP4M1	22
BP	GO:0046822	regulation of nucleocytoplasmic transport	22/2619	104/18670	0.03002	0.1242	0.09315	ZIC1/ECT2/ANGPT1/SMAD3/BARD1/NUP153/GSK3B/TPR/BMP4/PPP1R12A/IFNG/FERMT1/CAMK1/SETD2/TARDBP/GTSE1/TCF7L2/NCBP2/FLNA/UBR5/SMO/NUP62	22
BP	GO:0032648	regulation of interferon-beta production	12/2619	48/18670	0.03027	0.125	0.09376	IRF1/RIPK2/TBK1/POLR3C/REL/NMI/IRF3/RELB/TRAF3/PPM1B/RIOK3/TLR8	12
BP	GO:0046850	regulation of bone remodeling	12/2619	48/18670	0.03027	0.125	0.09376	TNFAIP3/SFRP1/TNFRSF11B/TFRC/CD38/EGFR/LTBP3/TNFRSF11A/S1PR1/IL6/SUCO/CA2	12
BP	GO:0072604	interleukin-6 secretion	12/2619	48/18670	0.03027	0.125	0.09376	CD200/IL27RA/SYT11/LILRA2/PTPN22/F2R/HMGB1/LPL/IL17RC/XBP1/TLR8/TWIST1	12
BP	GO:0010721	negative regulation of cell development	61/2619	344/18670	0.03034	0.1252	0.09389	BRINP1/GBP1/PTN/NOTCH1/DIO3/SOX9/STMN2/GAK/SEMA4D/FBXW7/ASPM/SEMA4A/SPOCK1/CD38/SEMA3A/FGF13/ASAP1/ZNF365/APOE/GSK3B/SEMA4C/EFNA5/ARHGEF2/DGUOK/MED1/PMP22/YWHAH/POSTN/ID4/CERS2/PLK2/NPR2/RGS4/KLK8/PCM1/SEMA3F/CTDP1/TSPO/IGF1/MAP4K4/IL6/TLX2/ITM2C/EPHA4/VEGFA/NR2F1/AP1AR/SEMA3E/PPP3CA/CIB1/SIX3/NGFR/OLIG2/ID2/ID3/GAL/ERBB4/FBLN1/COL3A1/BCL11A/LRIG2	61
BP	GO:0016050	vesicle organization	58/2619	325/18670	0.03039	0.1253	0.09401	TAP1/DYSF/FOLR1/SPHK1/SEC24A/SNCA/VPS37C/RAB27A/SERPINA1/ZFYVE16/SDC1/SPG11/SYNJ1/UVRAG/PPP6R3/AP2M1/BLOC1S1/SEC22B/STX10/VTI1B/SEC13/TAPBP/F8/CHMP6/F2R/VAMP3/VPS16/TRAPPC2L/CNIH1/TRAPPC10/SAMD9/PRKCI/LRMP/CHMP2A/SEC16A/VAMP7/SORT1/USP8/VPS8/TAP2/TMED2/SNX10/TMED9/TMED10/TMF1/CHMP1B/HOOK2/RAB20/CREB1/ANKRD28/SYT1/GOLPH3/VAPA/NAPA/DNAJC13/SRGN/CD59/FBXO5	58
BP	GO:0010517	regulation of phospholipase activity	16/2619	70/18670	0.0308	0.1269	0.09522	CCL5/SNCA/ITK/EGFR/NTRK2/NTF3/KIT/ARL1/HTR2B/SELE/AGT/ANG/TXK/PLA2R1/LPAR2/BDNF	16
BP	GO:0002220	innate immune response activating cell surface receptor signaling pathway	24/2619	116/18670	0.03093	0.1274	0.09555	PLCG2/SKP1/MALT1/PSMB9/LILRA2/PSMC2/NFKB1/RELB/PSMB6/CHUK/PSMC3/PSMD8/PSMB5/PSMD10/MUC5AC/IKBKG/RAF1/FCN1/PAK2/BCL10/EP300/KRAS/ICAM3/NRAS	24
BP	GO:0010518	positive regulation of phospholipase activity	14/2619	59/18670	0.03107	0.1279	0.09592	CCL5/ITK/EGFR/NTRK2/NTF3/KIT/ARL1/HTR2B/SELE/AGT/ANG/TXK/LPAR2/BDNF	14
BP	GO:0009200	deoxyribonucleoside triphosphate metabolic process	6/2619	18/18670	0.0312	0.128	0.09603	ADK/ADA/SAMHD1/DGUOK/GUK1/TYMS	6
BP	GO:0031065	positive regulation of histone deacetylation	6/2619	18/18670	0.0312	0.128	0.09603	PRKD2/NIPBL/PINK1/ING2/VEGFA/AKAP8	6
BP	GO:0060546	negative regulation of necroptotic process	6/2619	18/18670	0.0312	0.128	0.09603	BIRC3/SLC25A4/CFLAR/BIRC2/ARHGEF2/PELI1	6
BP	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	6/2619	18/18670	0.0312	0.128	0.09603	SIX1/SOX9/AGT/VEGFA/MAGED1/SMO	6
BP	GO:0050796	regulation of insulin secretion	34/2619	176/18670	0.03121	0.128	0.09603	SFRP1/JAK2/CCL5/RPH3AL/SRI/SLC25A4/MPC2/CD38/ARL2/RBP4/BAD/EFNA5/GPER1/TCIRG1/ARRB1/HADH/OXCT1/IFNG/ITPR2/SIRT3/LRP5/MAP4K4/GHSR/ARL2BP/ABCC8/ANO1/PPP3CA/SSTR5/HIF1A/TARDBP/CACNA1D/TCF7L2/ENSA/INHBB	34
BP	GO:0006282	regulation of DNA repair	25/2619	122/18670	0.03124	0.1281	0.09607	EYA2/PARP3/SMCHD1/CHEK1/TRIP12/EGFR/ZNF365/DDX11/MMS19/DEK/SETMAR/FOXM1/PML/HMGB1/UBQLN4/TIMELESS/SETD2/BABAM1/CEBPG/UBR5/CDK9/ACTR2/HMGA2/WDR70/TWIST1	25
BP	GO:0051260	protein homooligomerization	62/2619	351/18670	0.03136	0.1285	0.09637	GCH1/GBP1/ECT2/KCTD2/FIS1/COLEC12/CLU/ALOX5AP/SIGMAR1/HLA-G/SYT11/PCBD1/CBY1/IMPDH2/CCDC88C/HSD17B10/ACOT13/PRNP/ATXN10/APOE/GPX3/DPYS/IDE/RXRA/PRF1/SAMHD1/EHD3/KCNJ2/JMJD6/CRYAB/CAT/CD3E/TAF10/PFKM/APAF1/ACAT1/CHMP2A/ALDH9A1/CD3D/CRYZ/CD247/P2RX4/ALDH1A3/PKD2L1/PRND/RS1/MICU1/PEX14/SPAST/SRR/AQP2/MCOLN1/DFFB/GSDMD/BCL10/SYT1/KCND1/CRTC3/CD3G/RIOK3/LETM1/SLC1A1	62
BP	GO:0061337	cardiac conduction	29/2619	146/18670	0.03174	0.1294	0.09705	SCN1B/ATP1B1/FXYD1/ATP2A3/SRI/KCNQ1/KCNK15/FXYD6/BIN1/EHD3/KCNK3/ASPH/KCNJ2/ITPR2/NPR2/ATP2B2/AGT/CACNB2/KCNN2/AKAP9/RANGRF/ATP2B4/CACNA1D/KCND1/CXADR/CACNA2D3/FLNA/ATP2B1/CORIN	29
BP	GO:0032881	regulation of polysaccharide metabolic process	11/2619	43/18670	0.03175	0.1294	0.09705	ENPP1/EGF/GSK3B/INSR/DYRK2/NFKB1/IGF1/PDGFB/HAS2/PASK/SORBS1	11
BP	GO:0033173	calcineurin-NFAT signaling cascade	11/2619	43/18670	0.03175	0.1294	0.09705	CAMTA1/PRNP/GSK3B/MAPK7/DYRK2/IGF1/HOMER3/PPP3CA/ATP2B4/CIB1/FHL2	11
BP	GO:0034198	cellular response to amino acid starvation	11/2619	43/18670	0.03175	0.1294	0.09705	MAP3K5/DAP/MAPK3/FAS/SLC38A2/ATF3/RRAGA/RRAGD/CDKN1A/SESN1/ATF4	11
BP	GO:0045746	negative regulation of Notch signaling pathway	11/2619	43/18670	0.03175	0.1294	0.09705	NFKBIA/FBXW7/TSPAN15/EGFR/EGF/NOTCH4/GDPD5/ARRB1/DLK1/RITA1/JAG2	11
BP	GO:0060612	adipose tissue development	11/2619	43/18670	0.03175	0.1294	0.09705	FTO/CDK4/BBS4/OXCT1/ACAT1/LRP5/UBB/ID2/ATF2/XBP1/PIK3CA	11
BP	GO:1901658	glycosyl compound catabolic process	11/2619	43/18670	0.03175	0.1294	0.09705	FUCA1/GUSB/ENTPD4/ADA/APOBEC3C/DPYS/TYMP/PNP/APOBEC3B/AHCY/NT5E	11
BP	GO:1904646	cellular response to amyloid-beta	11/2619	43/18670	0.03175	0.1294	0.09705	TREM2/LGMN/PRNP/GSK3B/CASP4/ADRB2/IGF1/NAMPT/EPHA4/BCL2L2/NGFR	11
BP	GO:0048704	embryonic skeletal system morphogenesis	20/2619	93/18670	0.03182	0.1296	0.0972	SIX1/HOXA11/NIPBL/SMAD3/MDFI/BMP4/HOXB6/OSR2/HOXA4/SIX2/HOXB5/IFT140/IRX5/HOXD9/HOXA5/SETD2/HOXC11/HOXA7/TWIST1/SATB2	20
BP	GO:0030073	insulin secretion	39/2619	207/18670	0.03205	0.1305	0.09785	SFRP1/JAK2/CCL5/RPH3AL/SRI/SLC25A4/MPC2/CD38/ARL2/RBP4/BAD/EFNA5/GPER1/TCIRG1/ARRB1/HADH/OXCT1/IFNG/ITPR2/SIRT3/PTPRN2/LRP5/MAP4K4/GHSR/ARL2BP/ABCC8/ANO1/PPP3CA/SSTR5/HIF1A/IL1RN/TARDBP/CACNA1D/RAF1/GAL/RAB11B/TCF7L2/ENSA/INHBB	39
BP	GO:0070301	cellular response to hydrogen peroxide	21/2619	99/18670	0.03253	0.1322	0.09919	TNFAIP3/SPHK1/SETX/MAP3K5/ECT2/SIGMAR1/HGF/EZH2/PINK1/NQO1/MAPK7/PLEKHA1/ANKZF1/IL6/AXL/TRAP1/NET1/PRKAA1/CDK1/PYCR1/PSAP	21
BP	GO:0072527	pyrimidine-containing compound metabolic process	21/2619	99/18670	0.03253	0.1322	0.09919	THTPA/NME4/TK2/NME7/AGPAT1/ENTPD4/NME5/AGPAT5/TDG/APOBEC3C/DPYS/NME3/TYMP/CPS1/APOBEC3B/DCTD/CTPS1/TYMS/NT5E/ALDH6A1/PRPS1	21
BP	GO:0001667	ameboidal-type cell migration	79/2619	461/18670	0.03265	0.1326	0.09949	PTN/NOTCH1/FOLR1/LGMN/SOX9/PRKD2/SEMA4D/FBXW7/CXCL13/ANGPT1/MACF1/SEMA4A/SEMA3A/ADAM17/PFN2/STC1/ANGPT2/APOE/PRKX/PECAM1/AAMP/KIT/BMP4/SEMA4C/HTR2B/WNT11/CSNK2B/PPARG/GPX1/ITGB7/CD40/LAMA5/HSPB1/KRIT1/IFNG/PRR5L/PLK2/ARHGEF7/C5orf30/AGT/SEMA3F/NOS3/RAB13/FGF18/EFNB1/KDR/MAP4K4/HBEGF/CLASP1/PML/PDGFB/VEGFA/PLXND1/P2RX4/HMGB1/TNS1/FERMT1/SCG2/SEMA3E/MAP3K3/AMOTL2/PHACTR4/HIF1A/EMP2/HAS2/TAC1/CIB1/STAT5A/TIMP1/MAPRE2/ERBB4/SGPL1/PTK2B/SMO/SERPINF1/KANK2/TWIST1/ARSB/PIK3CA	79
BP	GO:0006084	acetyl-CoA metabolic process	10/2619	38/18670	0.03301	0.1339	0.1004	PDK2/PMVK/MPC2/GSTZ1/ACAT1/DLD/PDK1/PDHB/MPC1/MVK	10
BP	GO:0050716	positive regulation of interleukin-1 secretion	10/2619	38/18670	0.03301	0.1339	0.1004	AIM2/RIPK2/LILRA2/NLRP1/CARD8/HMGB1/NOD2/LPL/GSDMD/TLR8	10
BP	GO:0007091	metaphase/anaphase transition of mitotic cell cycle	13/2619	54/18670	0.0331	0.1339	0.1004	ATM/DLGAP5/TPR/BUB1B/LCMT1/NDC80/CENPE/CCNB1/CDC20/AURKB/TACC3/CENPF/FBXO5	13
BP	GO:0035384	thioester biosynthetic process	13/2619	54/18670	0.0331	0.1339	0.1004	PDK2/SNCA/MPC2/TECR/SLC25A1/ACSL5/GSTZ1/ACAT1/DLD/SCD5/PDK1/PDHB/MPC1	13
BP	GO:0071616	acyl-CoA biosynthetic process	13/2619	54/18670	0.0331	0.1339	0.1004	PDK2/SNCA/MPC2/TECR/SLC25A1/ACSL5/GSTZ1/ACAT1/DLD/SCD5/PDK1/PDHB/MPC1	13
BP	GO:0001841	neural tube formation	22/2619	105/18670	0.03311	0.1339	0.1004	SFRP1/FOLR1/TCTN1/IFT52/RALA/BMP4/SEMA4C/FZD3/BBS4/ARID1A/APAF1/DEAF1/ARHGAP35/GLMN/TMED2/PHACTR4/HIF1A/SETD2/BCL10/FZD6/TWIST1/FZD2	22
BP	GO:0033138	positive regulation of peptidyl-serine phosphorylation	22/2619	105/18670	0.03311	0.1339	0.1004	PRKD2/RIPK2/TBK1/ANGPT1/SNCA/EGFR/PFN2/PINK1/NTRK2/NTF3/ARRB1/CD44/IFNG/IL6/VEGFA/CALCR/CAMK1/AKAP9/ATP2B4/RAF1/CAPRIN2/PIK3CA	22
BP	GO:0032637	interleukin-8 production	18/2619	82/18670	0.03345	0.1348	0.1011	PRKD2/PTPRC/LILRA2/SERPINE1/PTPN22/ARRB1/ELANE/F2R/TLR5/NOD2/CD58/CD2/NOD1/FCN1/BCL10/MYD88/TLR8/DDIT3	18
BP	GO:0007064	mitotic sister chromatid cohesion	7/2619	23/18670	0.03352	0.1348	0.1011	NIPBL/SMC5/NAA50/CDC20/ATRX/SMC1A/POGZ	7
BP	GO:0009068	aspartate family amino acid catabolic process	7/2619	23/18670	0.03352	0.1348	0.1011	ALDH7A1/SDS/GOT1/DDO/GCAT/ASRGL1/DLD	7
BP	GO:0010528	regulation of transposition	7/2619	23/18670	0.03352	0.1348	0.1011	MYBL1/UBR2/APOBEC3C/APOBEC3B/ZNF93/PIWIL2/ZNF91	7
BP	GO:0010529	negative regulation of transposition	7/2619	23/18670	0.03352	0.1348	0.1011	MYBL1/UBR2/APOBEC3C/APOBEC3B/ZNF93/PIWIL2/ZNF91	7
BP	GO:0019400	alditol metabolic process	7/2619	23/18670	0.03352	0.1348	0.1011	AKR1B1/DYSF/GOT1/SORD/GK/PCK2/COQ2	7
BP	GO:0032703	negative regulation of interleukin-2 production	7/2619	23/18670	0.03352	0.1348	0.1011	TNFAIP3/GBP1/PTPRC/PRNP/XCL1/HOMER3/KAT5	7
BP	GO:0032753	positive regulation of interleukin-4 production	7/2619	23/18670	0.03352	0.1348	0.1011	HLA-E/CD28/CD3E/TNFSF4/PRKCQ/CEBPB/CD40LG	7
BP	GO:0034695	response to prostaglandin E	7/2619	23/18670	0.03352	0.1348	0.1011	SFRP1/PPARG/PTGER4/TNFSF4/CCR7/AKAP8/PRKAA1	7
BP	GO:0060401	cytosolic calcium ion transport	33/2619	171/18670	0.03383	0.1358	0.1018	CXCL9/CXCL10/PLCG2/SNCA/SRI/CXCL11/PTPRC/PRNP/CCR5/NOL3/HTR2B/GPER1/F2R/LCK/ITPR2/MCOLN3/PML/FAM155A/XCL1/CD19/P2RX4/CALCR/PLCE1/CCR7/MICU1/LIME1/TPCN1/MCOLN1/ATP2B4/MS4A1/PTK2B/LETM1/DDIT3	33
BP	GO:0007254	JNK cascade	40/2619	214/18670	0.03387	0.1358	0.1018	TPD52L1/SFRP1/MAP3K5/RASGRP1/RIPK2/SLAMF1/TNIK/SEMA3A/EGFR/MAP3K11/PINK1/TNFRSF11A/BIRC7/DNAJA1/PTPN22/PTGER4/MAP4K1/CD27/DAXX/TRIB1/TAOK1/MAP4K4/IRAK4/EPHA4/MFHAS1/UBB/HMGB1/CCR7/NOD2/NCOR1/CYLD/IL1RN/TAOK3/NOD1/IKBKG/PHLPP1/PTK2B/FZD7/CD40LG/NCF1	40
BP	GO:0010822	positive regulation of mitochondrion organization	24/2619	117/18670	0.03391	0.1358	0.1018	FAM162A/TREM2/FIS1/FBXW7/VPS13C/MICALL2/BAD/PINK1/GSK3B/GZMB/PPP1R13B/GPER1/YWHAH/TP53BP2/KDR/RAC2/ATG13/OPTN/CIDEB/HIF1A/PRKAA1/HIP1R/UBL5/STOML2	24
BP	GO:0001914	regulation of T cell mediated cytotoxicity	9/2619	33/18670	0.03391	0.1358	0.1018	HLA-C/HLA-F/HLA-G/IL7R/HLA-A/PTPRC/HLA-B/HLA-E/XCL1	9
BP	GO:0002756	MyD88-independent toll-like receptor signaling pathway	9/2619	33/18670	0.03391	0.1358	0.1018	BIRC3/TBK1/TNIP3/BIRC2/IRF3/CHUK/UBB/TRAF3/IKBKG	9
BP	GO:0070232	regulation of T cell apoptotic process	9/2619	33/18670	0.03391	0.1358	0.1018	CCL5/IL7R/IDO1/ADA/BMP4/CD27/PRKCQ/HIF1A/LGALS3	9
BP	GO:2000352	negative regulation of endothelial cell apoptotic process	9/2619	33/18670	0.03391	0.1358	0.1018	TNFAIP3/NDNF/ANGPT1/TNIP2/SERPINE1/MAPK7/KRIT1/KDR/SCG2	9
BP	GO:0008045	motor neuron axon guidance	8/2619	28/18670	0.03421	0.1364	0.1023	MYCBP2/SEMA3A/CHN1/ERBB2/KIF5C/SEMA3F/RAC2/EPHA4	8
BP	GO:0009065	glutamine family amino acid catabolic process	8/2619	28/18670	0.03421	0.1364	0.1023	FAH/DDAH1/GOT1/ASRGL1/DDAH2/NOS3/OAT/ATP2B4	8
BP	GO:0032196	transposition	8/2619	28/18670	0.03421	0.1364	0.1023	MYBL1/UBR2/APOBEC3C/APOBEC3B/ZNF93/L1TD1/PIWIL2/ZNF91	8
BP	GO:0060260	regulation of transcription initiation from RNA polymerase II promoter	8/2619	28/18670	0.03421	0.1364	0.1023	ATF7IP/CTNNBIP1/ZNF451/PSMC2/PSMC3/TAF7/HMGB1/CREB1	8
BP	GO:0060512	prostate gland morphogenesis	8/2619	28/18670	0.03421	0.1364	0.1023	SFRP1/NOTCH1/AR/SOX9/RXRA/BMP4/CYP7B1/ID4	8
BP	GO:0085029	extracellular matrix assembly	8/2619	28/18670	0.03421	0.1364	0.1023	NOTCH1/EFEMP2/SOX9/MFAP4/FBLN5/SMAD3/AGT/HAS2	8
BP	GO:0090263	positive regulation of canonical Wnt signaling pathway	29/2619	147/18670	0.03442	0.137	0.1028	SFRP1/GPC5/SMAD3/ASPM/TNKS2/PSMB9/NLE1/EGFR/EGF/ZBED2/PLEKHA4/PSMC2/USP47/USP34/NFKB1/PSMB6/WLS/PSMC3/RBPJ/PIN1/USP8/PSMD8/LGR5/PSMB5/FRAT1/CSNK1E/PSMD10/CAPRIN2/UBR5	29
BP	GO:1903557	positive regulation of tumor necrosis factor superfamily cytokine production	19/2619	88/18670	0.03445	0.137	0.1028	JAK2/RASGRP1/RIPK2/CLU/PTPRC/LILRA2/HLA-E/ARHGEF2/HSPB1/IFNG/TYROBP/HMGB1/NOD2/MAPKAPK2/LPL/CD2/NOD1/CCR2/TWIST1	19
BP	GO:2000177	regulation of neural precursor cell proliferation	19/2619	88/18670	0.03445	0.137	0.1028	PTN/NOTCH1/CDH2/ASPM/EGF/SMARCD3/CX3CR1/FZD3/INSM1/SHCBP1/PTBP2/VEGFA/DCT/HIF1A/NF2/SIX3/ID2/FLNA/SMO	19
BP	GO:0008286	insulin receptor signaling pathway	28/2619	141/18670	0.03445	0.137	0.1028	PTPRE/PDK2/ENPP1/SH2B2/ATP6V0D1/PRKCB/SOS1/PID1/BAIAP2/GSK3B/INSR/CDK4/SOCS1/IDE/OSBPL8/PTPN2/TCIRG1/GRB10/MZB1/PHIP/AGT/ATP6V0E2/PRKCQ/OGT/PRKAA1/CISH/PIK3CA/SORBS1	28
BP	GO:0030857	negative regulation of epithelial cell differentiation	12/2619	49/18670	0.03514	0.1395	0.1047	NOTCH1/STAT1/SOX9/EZH2/NOTCH4/GSK3B/IFNG/VEGFA/FOXJ2/HOXA7/SMO/REG3A	12
BP	GO:0045010	actin nucleation	12/2619	49/18670	0.03514	0.1395	0.1047	IQGAP2/ACTR3B/ARPC1A/FCHSD2/ACTR3/MAGEL2/SCIN/AP1AR/ARPC5L/HIP1R/CYFIP1/ACTR2	12
BP	GO:0048546	digestive tract morphogenesis	12/2619	49/18670	0.03514	0.1395	0.1047	SFRP1/NOTCH1/NIPBL/SMAD3/TCF7/EGFR/BMP4/WNT11/FOXF1/SIX2/HIF1A/ID2	12
BP	GO:0033260	nuclear DNA replication	14/2619	60/18670	0.03547	0.1407	0.1055	CDC7/POLD2/CHEK2/DNA2/ORC3/RPA1/DBF4/RPA3/POLD4/DONSON/GINS1/BRCA2/ATRX/RFC2	14
BP	GO:0045576	mast cell activation	14/2619	60/18670	0.03547	0.1407	0.1055	RASGRP1/IL4R/S100A13/KIT/FGR/FOXF1/RAC2/VAMP7/LAT/PIK3CD/RHOH/S100A12/LCP2/IL13RA2	14
BP	GO:0001771	immunological synapse formation	5/2619	14/18670	0.03615	0.1421	0.1066	NCK2/PRF1/CD81/CCR7/LGALS3	5
BP	GO:0003214	cardiac left ventricle morphogenesis	5/2619	14/18670	0.03615	0.1421	0.1066	NOTCH1/FOXF1/TBX5/RBPJ/CPE	5
BP	GO:0006241	CTP biosynthetic process	5/2619	14/18670	0.03615	0.1421	0.1066	NME4/NME7/NME5/NME3/CTPS1	5
BP	GO:0014841	skeletal muscle satellite cell proliferation	5/2619	14/18670	0.03615	0.1421	0.1066	SIX1/JAK2/ANGPT1/CFLAR/PAXBP1	5
BP	GO:0014857	regulation of skeletal muscle cell proliferation	5/2619	14/18670	0.03615	0.1421	0.1066	SIX1/JAK2/ANGPT1/CFLAR/PAXBP1	5
BP	GO:0043374	CD8-positive, alpha-beta T cell differentiation	5/2619	14/18670	0.03615	0.1421	0.1066	IRF1/RUNX3/SOCS1/SATB1/TNFSF8	5
BP	GO:0045591	positive regulation of regulatory T cell differentiation	5/2619	14/18670	0.03615	0.1421	0.1066	BTN2A2/HLA-G/LILRB2/SOCS1/IFNG	5
BP	GO:0046036	CTP metabolic process	5/2619	14/18670	0.03615	0.1421	0.1066	NME4/NME7/NME5/NME3/CTPS1	5
BP	GO:0046629	gamma-delta T cell activation	5/2619	14/18670	0.03615	0.1421	0.1066	MICB/PTPRC/NOD2/JAG2/CXADR	5
BP	GO:0048266	behavioral response to pain	5/2619	14/18670	0.03615	0.1421	0.1066	THBS4/NTRK1/TSPO/P2RX4/SCN9A	5
BP	GO:0050720	interleukin-1 beta biosynthetic process	5/2619	14/18670	0.03615	0.1421	0.1066	JAK2/CMA1/IFNG/EGR1/TYROBP	5
BP	GO:1902656	calcium ion import into cytosol	5/2619	14/18670	0.03615	0.1421	0.1066	PRNP/FAM155A/CALCR/ATP2B4/MS4A1	5
BP	GO:2001044	regulation of integrin-mediated signaling pathway	5/2619	14/18670	0.03615	0.1421	0.1066	CD63/PHACTR4/EMP2/TIMP1/FLNA	5
BP	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	17/2619	77/18670	0.03616	0.1421	0.1066	NOTCH1/PSMB9/BACH1/PSMC2/PSMB6/PSMC3/EGR1/RBPJ/VEGFA/PSMD8/UBB/EGLN3/PSMB5/PSMD10/HIF1A/EP300/CUL2	17
BP	GO:0002286	T cell activation involved in immune response	22/2619	106/18670	0.03644	0.1429	0.1072	LCP1/RIPK2/MALT1/RORA/RAB27A/SEMA4A/IL4R/GPR183/ITGAL/LEF1/PTGER4/RC3H2/CD81/RELB/IFNG/LY9/IL6/SLC11A1/TNFSF4/HMGB1/BATF/LGALS3	22
BP	GO:0007041	lysosomal transport	22/2619	106/18670	0.03644	0.1429	0.1072	DENND3/GAK/CLU/ZFYVE16/PINK1/GNPTAB/BIN1/EHD3/TRAK1/ADRB2/VPS16/VAMP7/GPRASP1/USE1/SORT1/HOOK2/NPC1/PSAP/CLEC16A/AP4M1/ARSB/HMGXB4	22
BP	GO:0044774	mitotic DNA integrity checkpoint	22/2619	106/18670	0.03644	0.1429	0.1072	TOPBP1/NBN/RFWD3/CRADD/CHEK2/ATM/DONSON/SETMAR/PLK2/CCNB1/TAOK1/PML/TOP2A/TAOK3/GTSE1/CDK1/RAD9A/CDKN1A/ATF2/EP300/HMGA2/RBL2	22
BP	GO:0070838	divalent metal ion transport	82/2619	483/18670	0.03648	0.143	0.1073	CXCL9/DYSF/CXCL10/ATP1B1/CCL5/ATP2A3/PLCG2/SNCA/SRI/CXCL11/PRKCB/LILRB2/PTPRC/FGF14/LILRA2/EGF/ATP2C1/PRNP/ZDHHC17/STC1/BIN1/CCR5/NOL3/HTR2B/EHD3/KCNJ2/PHB/GPER1/CXCR4/TSPAN13/GPM6A/F2R/TMCO1/CCL8/IFNG/LCK/ITPR2/RGS4/MCOLN3/SLC39A8/ATP2B2/AGT/TSPO/NOS3/S100A1/HCRT/PML/FAM155A/PDGFB/XCL1/SLC11A1/CD19/P2RX4/CALCR/PLCE1/PKD2L1/CCR7/HOMER3/MICU1/PPP3CA/CACNB2/SLC39A14/ORAI3/REM1/LIME1/TPCN1/MCOLN1/ATP2B4/CACNA1D/TRPV2/LGALS3/HSPA2/CACNA2D3/MS4A1/YME1L1/PTK2B/STOML2/LETM1/CAMK2B/STC2/ATP2B1/DDIT3	82
BP	GO:0090257	regulation of muscle system process	47/2619	259/18670	0.03681	0.1442	0.1082	SGCA/NOTCH1/SPHK1/JARID2/ATP1B1/TNFRSF1B/IGFBP5/TACR2/SRI/SMAD3/KCNQ1/MTMR4/GTF2IRD1/FGF13/STC1/ADA/KIT/BIN1/HSPB6/NOL3/EHD3/ROCK1/KCNJ2/MYL3/GPER1/F2R/ADRB2/RGS4/CHRNA3/AGT/CTDP1/IGF1/NOS3/GHSR/PIN1/P2RX4/PLCE1/PPP3CA/SOD1/AKAP9/RANGRF/CTTN/ATP2B4/FLNA/CDK9/CAMK2B/ATP2B1	47
BP	GO:0046661	male sex differentiation	31/2619	160/18670	0.03692	0.1446	0.1084	HOXA11/SFRP1/NUPR1/AR/HOXA10/KDM5A/SOX9/ERCC1/ASPM/SDC1/SEMA3A/ARID4B/INSR/KIT/ING2/PLEKHA1/NTRK1/ZFPM2/RAB13/NASP/AKR1C3/ATRX/UBB/DHCR24/ARID4A/TMF1/MEA1/BCL2L2/PATZ1/SGPL1/FLNA	31
BP	GO:0061025	membrane fusion	30/2619	154/18670	0.03711	0.1452	0.1089	TAP1/DYSF/SPHK1/BNIP1/SNCA/SERPINA5/SPG11/UVRAG/CCR5/SEC22B/STX10/VTI1B/TAPBP/CXCR4/TIE1/FOLR2/VAMP3/VPS16/SAMD9/LRMP/VAMP7/VPS8/TAP2/VAMP2/ANXA7/GCA/RAB20/SYT1/VAPA/NAPA	30
BP	GO:0007080	mitotic metaphase plate congression	11/2619	44/18670	0.03714	0.1452	0.1089	CDCA8/CHMP6/NDC80/CENPE/CHMP2A/CCNB1/MIS12/KPNB1/CHMP1B/CENPC/NUP62	11
BP	GO:0035307	positive regulation of protein dephosphorylation	11/2619	44/18670	0.03714	0.1452	0.1089	JAK2/CAMTA1/LILRB2/PTPRC/PINK1/MAGI2/PPP1R16B/CDH5/PPP1R12A/PIN1/ANKLE2	11
BP	GO:0010498	proteasomal protein catabolic process	81/2619	477/18670	0.03727	0.1455	0.1091	NUPR1/CEBPA/TREM2/SOCS6/KCTD2/FBXW7/SDF2/SKP1/CLU/LAMP3/HERPUD1/GABARAPL2/ERLIN2/UCHL1/UBR2/PSMB9/CBFA2T3/AREL1/UBE2J1/PTTG1/PINK1/APOE/GSK3B/BIRC2/CHFR/DNAJB14/HFE/BUB1B/RCN3/FBXO17/PSMC2/FBXL2/LTN1/GPX1/FHIT/UBXN4/ARRB1/PELI1/PLK2/PSMB6/TRIB1/ANKZF1/DET1/CCNB1/PSMC3/MAN1B1/PML/CDC20/CSNK1A1/AURKB/RNF19B/PSMD8/UBB/UBQLN4/GLMN/PSMB5/CSNK1E/RNF187/EDEM1/KAT5/NFE2L1/UBXN8/PSMD10/TMF1/OGT/RYBP/CDK1/RNF14/N4BP1/CUL2/FBXO38/TRIM2/HSPA5/SEL1L/CLEC16A/DDIT3/USP14/RNF34/NEDD4L/NEMF/FBXO5	81
BP	GO:0051209	release of sequestered calcium ion into cytosol	25/2619	124/18670	0.03729	0.1455	0.1091	CXCL9/CXCL10/PLCG2/SNCA/SRI/CXCL11/PTPRC/CCR5/NOL3/HTR2B/GPER1/F2R/LCK/ITPR2/MCOLN3/XCL1/CD19/PLCE1/CCR7/LIME1/TPCN1/MCOLN1/PTK2B/LETM1/DDIT3	25
BP	GO:0006970	response to osmotic stress	18/2619	83/18670	0.03731	0.1455	0.1091	AKR1B1/DYSF/MAP7/BAD/EGFR/SORD/SERPINB6/ARHGEF2/RELB/TSPO/MICU1/ABCB1/ANXA7/HNMT/ATF2/PTK2B/LETM1/TH	18
BP	GO:0008652	cellular amino acid biosynthetic process	18/2619	83/18670	0.03731	0.1455	0.1091	CBS/BHMT2/THNSL2/GAMT/GOT1/NAALAD2/SERINC5/GATM/ASS1/PSPH/CPS1/OAT/SRR/ATP2B4/SEPHS1/PYCR1/ALDH18A1/ASNS	18
BP	GO:0045428	regulation of nitric oxide biosynthetic process	15/2619	66/18670	0.03745	0.1459	0.1094	JAK2/CLU/SMAD3/DDAH1/CX3CR1/INSR/DDAH2/IFNG/AGT/ASS1/TSPO/P2RX4/HBB/ATP2B4/PTK2B	15
BP	GO:0032613	interleukin-10 production	13/2619	55/18670	0.03797	0.1476	0.1107	TREM2/HGF/TNFRSF21/IDO1/CD83/CD28/TUSC2/TYROBP/XCL1/TNFSF4/HMGB1/NOD2/CD40LG	13
BP	GO:0042306	regulation of protein import into nucleus	13/2619	55/18670	0.03797	0.1476	0.1107	ZIC1/ECT2/ANGPT1/SMAD3/TPR/BMP4/IFNG/FERMT1/TARDBP/FLNA/UBR5/SMO/NUP62	13
BP	GO:0043030	regulation of macrophage activation	13/2619	55/18670	0.03797	0.1476	0.1107	CEBPA/SPHK1/TREM2/CD200/SNCA/RORA/TNIP2/IL4R/PTPRC/ATM/IL6/MFHAS1/CST7	13
BP	GO:0048016	inositol phosphate-mediated signaling	13/2619	55/18670	0.03797	0.1476	0.1107	CAMTA1/PRNP/GSK3B/MAPK7/DYRK2/ITPR2/IGF1/PLCE1/HOMER3/PPP3CA/ATP2B4/CIB1/FHL2	13
BP	GO:0046328	regulation of JNK cascade	35/2619	185/18670	0.03838	0.1491	0.1118	TPD52L1/SFRP1/MAP3K5/RASGRP1/RIPK2/SLAMF1/TNIK/SEMA3A/EGFR/MAP3K11/PINK1/TNFRSF11A/BIRC7/DNAJA1/PTPN22/MAP4K1/CD27/DAXX/TAOK1/MAP4K4/EPHA4/MFHAS1/HMGB1/CCR7/NOD2/NCOR1/CYLD/IL1RN/TAOK3/NOD1/PHLPP1/PTK2B/FZD7/CD40LG/NCF1	35
BP	GO:0030198	extracellular matrix organization	64/2619	368/18670	0.03871	0.1503	0.1127	KAZALD1/TPSAB1/NOTCH1/NDNF/LCP1/TNFRSF1B/EFEMP2/TNFRSF11B/SOX9/ADAM19/LAMC3/CRISPLD2/MFAP4/FBLN5/SMAD3/CFLAR/FOXC1/ITGAX/ITGAL/ITGA5/ITGAE/BSG/TIMP2/SERPINE1/CAPNS1/PECAM1/HTRA1/ADAMTSL2/CMA1/PXDN/ITGB7/LAMA5/CD44/ELANE/FOXF1/POSTN/COL15A1/AGT/COMP/KDR/IL6/MMP13/HAPLN1/CLASP1/PDGFB/MMP12/ADAMTS3/FERMT1/COL5A3/COL6A3/SPOCK2/ERCC2/HAS2/MMP20/CTSG/ITGB5/MPV17/COL4A1/TIMP1/VCAN/FBLN1/COL3A1/COL4A2/ICAM3	64
BP	GO:0030900	forebrain development	66/2619	381/18670	0.03898	0.1507	0.1131	PITX1/PTN/NOTCH1/TCTN1/CDH2/NDE1/ASPM/SLC7A11/BCL2A1/SEMA3A/EZH2/SYNE2/FGF13/BAD/AGTPBP1/SLC38A2/EGFR/NTRK2/GSK3B/BCL11B/BMP4/LEF1/GDPD5/GNG12/BBS4/CXCR4/ARID1A/ID4/APAF1/PCM1/RBPJ/AXL/TYROBP/ATRX/ALDH1A3/UBB/ARHGAP35/TSKU/TACC2/DCT/NRGN/HIF1A/HDAC1/SETD2/NF2/UQCRQ/ATP2B4/SIX3/CREB1/TACC3/OLIG2/ID2/TMEM14B/CCKAR/TYRO3/ERBB4/COL3A1/FABP7/FLNA/KRAS/C21orf91/SMO/EMX2/MYH10/TH/SATB2	66
BP	GO:0061326	renal tubule development	20/2619	95/18670	0.03899	0.1507	0.1131	SIX1/HOXA11/NOTCH1/STAT1/SOX9/PGF/CTNNBIP1/BMP4/WNT11/KLHL3/LAMA5/ACAT1/AGT/SIX2/MYC/VEGFA/MAGED1/LGR5/COL4A1/SMO	20
BP	GO:0032506	cytokinetic process	10/2619	39/18670	0.039	0.1507	0.1131	ECT2/RACGAP1/CEP55/CHMP6/CHMP2A/AURKB/SPAST/CHMP1B/KIF20A/NUP62	10
BP	GO:0033683	nucleotide-excision repair, DNA incision	10/2619	39/18670	0.039	0.1507	0.1131	ERCC1/POLD2/RPA1/RPA3/POLD4/UBB/DDB2/ERCC2/GTF2H3/RFC2	10
BP	GO:0042769	DNA damage response, detection of DNA damage	10/2619	39/18670	0.039	0.1507	0.1131	POLD2/RPA1/DNAJA1/RPA3/POLD4/UBB/DTL/MRPS11/RFC2/HMGA2	10
BP	GO:0045911	positive regulation of DNA recombination	10/2619	39/18670	0.039	0.1507	0.1131	TFRC/PTPRC/MMS19/CD28/CD40/TNFSF4/WRN/ERCC2/TIMELESS/ACTR2	10
BP	GO:2000826	regulation of heart morphogenesis	10/2619	39/18670	0.039	0.1507	0.1131	SIX1/NOTCH1/SOX9/FOXC1/PIM1/BMP4/TBX5/RBPJ/SMO/TWIST1	10
BP	GO:0060193	positive regulation of lipase activity	16/2619	72/18670	0.03908	0.151	0.1132	CCL5/ITK/EGFR/NTRK2/NTF3/KIT/ARL1/HTR2B/SELE/AGT/NR1H2/ANG/TXK/LPAR2/BDNF/LMF1	16
BP	GO:0035051	cardiocyte differentiation	32/2619	167/18670	0.03948	0.1512	0.1134	SIK1/NOTCH1/FOLR1/MAPK3/CBY1/SGCB/EGFR/MYOM2/RXRA/BMP4/GPER1/NEBL/ARID1A/MAML1/RGS4/AGT/CTDP1/IGF1/TBX5/CCNB1/FHOD3/RBPJ/SORBS2/VEGFA/PIN1/AKAP13/CDK1/CXADR/FZD7/MYH10/TENM4/TWIST1	32
BP	GO:0016073	snRNA metabolic process	21/2619	101/18670	0.03957	0.1512	0.1134	POLR2J/POLR2I/POLR2L/EXOSC7/POLR2E/POLR2F/NHP2/USPL1/INTS6/POLR2C/INTS8/POU2F1/CCNT2/GTF2A2/POLR2G/NABP2/ELL2/CCNK/NCBP2/CDK9/MEPCE	21
BP	GO:0031532	actin cytoskeleton reorganization	21/2619	101/18670	0.03957	0.1512	0.1134	MICALL2/TNIK/ATP2C1/BAIAP2/NEDD9/RALA/NTF3/KIT/PDLIM4/SIPA1L1/S1PR1/THSD7A/AUTS2/SEMA3E/PARVB/CTTN/CXADR/FLNA/PTK2B/EFS/GDPD2	21
BP	GO:0046545	development of primary female sexual characteristics	21/2619	101/18670	0.03957	0.1512	0.1134	SFRP1/NUPR1/FOXC1/ATM/INSR/KIT/PLEKHA1/ARRB1/ZFPM2/NOS3/ANG/BRCA2/EREG/VEGFA/UBB/SOD1/GDF9/SGPL1/INHBB/CEBPB/HSPA5	21
BP	GO:0045766	positive regulation of angiogenesis	38/2619	204/18670	0.03962	0.1512	0.1134	SPHK1/PRKD2/PGF/DDAH1/PRKCB/HGF/ITGAX/ITGA5/CX3CR1/SERPINE1/ANGPT2/HSPB6/JAK1/CMA1/PPP1R16B/CD40/CXCR4/TIE1/HSPB1/CDH5/PLK2/NOS3/FGF18/S100A1/KDR/GHSR/MTDH/VEGFA/CXCR2/MAP3K3/HIF1A/CIB1/XBP1/CXCL8/PTK2B/HMGA2/TWIST1/VEGFB	38
BP	GO:1903707	negative regulation of hemopoiesis	30/2619	155/18670	0.04006	0.1512	0.1134	NFKBIA/SFRP1/NOTCH1/IRF1/FBXW7/TCTA/HLA-G/IL4R/WDR61/CTLA4/GPR171/RUNX3/N4BP2L2/SOCS1/BMP4/ERBB2/PTPN2/RC3H2/TRIB1/RBM15/HMGB3/MYC/TNFSF4/HMGB1/HOXA5/PRDX2/CIB1/ID2/PTK2B/HOXA7	30
BP	GO:0001787	natural killer cell proliferation	4/2619	10/18670	0.04018	0.1512	0.1134	ELF4/IL15/HLA-E/PTPN22	4
BP	GO:0002713	negative regulation of B cell mediated immunity	4/2619	10/18670	0.04018	0.1512	0.1134	PARP3/THOC1/CR1/C4BPB	4
BP	GO:0002890	negative regulation of immunoglobulin mediated immune response	4/2619	10/18670	0.04018	0.1512	0.1134	PARP3/THOC1/CR1/C4BPB	4
BP	GO:0006228	UTP biosynthetic process	4/2619	10/18670	0.04018	0.1512	0.1134	NME4/NME7/NME5/NME3	4
BP	GO:0006307	DNA dealkylation involved in DNA repair	4/2619	10/18670	0.04018	0.1512	0.1134	FTO/MPG/ASCC3/ASCC1	4
BP	GO:0009157	deoxyribonucleoside monophosphate biosynthetic process	4/2619	10/18670	0.04018	0.1512	0.1134	TK2/DGUOK/DCTD/TYMS	4
BP	GO:0016559	peroxisome fission	4/2619	10/18670	0.04018	0.1512	0.1134	FIS1/PEX19/PEX11A/ACOT8	4
BP	GO:0032463	negative regulation of protein homooligomerization	4/2619	10/18670	0.04018	0.1512	0.1134	CLU/CRYAB/PEX14/RIOK3	4
BP	GO:0033182	regulation of histone ubiquitination	4/2619	10/18670	0.04018	0.1512	0.1134	TRIP12/UBR5/CDK9/WDR70	4
BP	GO:0035672	oligopeptide transmembrane transport	4/2619	10/18670	0.04018	0.1512	0.1134	SLC7A11/ABCC1/CA2/SLC15A2	4
BP	GO:0045713	low-density lipoprotein particle receptor biosynthetic process	4/2619	10/18670	0.04018	0.1512	0.1134	SEC24A/CNPY2/HNRNPK/PPARG	4
BP	GO:0045876	positive regulation of sister chromatid cohesion	4/2619	10/18670	0.04018	0.1512	0.1134	NIPBL/DDX11/SMC5/SFPQ	4
BP	GO:0048340	paraxial mesoderm morphogenesis	4/2619	10/18670	0.04018	0.1512	0.1134	SMAD3/FOXC1/WNT11/LEF1	4
BP	GO:0051231	spindle elongation	4/2619	10/18670	0.04018	0.1512	0.1134	RACGAP1/PRC1/KIF4A/AURKB	4
BP	GO:0051409	response to nitrosative stress	4/2619	10/18670	0.04018	0.1512	0.1134	DUSP6/ATM/DNAJA1/DDIT3	4
BP	GO:0060068	vagina development	4/2619	10/18670	0.04018	0.1512	0.1134	RBP4/MERTK/AXL/TYRO3	4
BP	GO:0070942	neutrophil mediated cytotoxicity	4/2619	10/18670	0.04018	0.1512	0.1134	DNASE1L3/ELANE/TUSC2/CTSG	4
BP	GO:0071104	response to interleukin-9	4/2619	10/18670	0.04018	0.1512	0.1134	STAT1/IL2RG/JAK1/STAT5A	4
BP	GO:0106049	regulation of cellular response to osmotic stress	4/2619	10/18670	0.04018	0.1512	0.1134	BAD/ARHGEF2/MICU1/LETM1	4
BP	GO:1901725	regulation of histone deacetylase activity	4/2619	10/18670	0.04018	0.1512	0.1134	KDM5A/PRKD2/PINK1/VEGFA	4
BP	GO:1903862	positive regulation of oxidative phosphorylation	4/2619	10/18670	0.04018	0.1512	0.1134	NUPR1/PINK1/CCNB1/CDK1	4
BP	GO:1904338	regulation of dopaminergic neuron differentiation	4/2619	10/18670	0.04018	0.1512	0.1134	SFRP1/GSK3B/FGF20/CSNK1E	4
BP	GO:2000109	regulation of macrophage apoptotic process	4/2619	10/18670	0.04018	0.1512	0.1134	CCL5/CCR5/GHSR/NOD2	4
BP	GO:0008277	regulation of G protein-coupled receptor signaling pathway	29/2619	149/18670	0.04028	0.1512	0.1134	CCL5/RPH3AL/GIT2/SNCA/ABHD6/RGS1/METAP1/ADA/PRMT5/HTR2B/ROCK1/PHB/KLK14/GPER1/GUCA1A/ARRB1/ADRB2/RGS4/TMOD2/GPRASP1/CALCR/PLCE1/ATP2B4/GRK6/RGS13/METAP2/CRY1/CXCL8/FZD2	29
BP	GO:0050701	interleukin-1 secretion	14/2619	61/18670	0.04031	0.1512	0.1134	TNFAIP3/AIM2/RIPK2/S100A13/LILRA2/NLRP1/CARD8/PML/HMGB1/CCR7/NOD2/LPL/GSDMD/TLR8	14
BP	GO:0043244	regulation of protein complex disassembly	23/2619	113/18670	0.04031	0.1512	0.1134	SETX/IRAK3/STMN2/TMOD1/FGF13/UVRAG/INSR/MTRF1/CAPZA1/ARHGEF2/ASPH/ADRB2/TAOK1/TMOD2/CLASP1/SCIN/UBQLN4/SCAF4/SPAST/KATNB1/CIB1/LIMA1/CLEC16A	23
BP	GO:0002313	mature B cell differentiation involved in immune response	6/2619	19/18670	0.04034	0.1512	0.1134	PLCG2/GPR183/DOCK10/ADA/XBP1/PTK2B	6
BP	GO:0002544	chronic inflammatory response	6/2619	19/18670	0.04034	0.1512	0.1134	TNFAIP3/CCL5/CXCL13/IDO1/AHCY/VNN1	6
BP	GO:0002710	negative regulation of T cell mediated immunity	6/2619	19/18670	0.04034	0.1512	0.1134	HLA-F/HLA-G/IL7R/PTPRC/HFE/XCL1	6
BP	GO:0006337	nucleosome disassembly	6/2619	19/18670	0.04034	0.1512	0.1134	SMARCD3/SET/ARID1A/PBRM1/SMARCD2/HMGA1	6
BP	GO:0009148	pyrimidine nucleoside triphosphate biosynthetic process	6/2619	19/18670	0.04034	0.1512	0.1134	NME4/NME7/NME5/NME3/CTPS1/TYMS	6
BP	GO:0010888	negative regulation of lipid storage	6/2619	19/18670	0.04034	0.1512	0.1134	NFKBIA/OSBPL8/PPARG/PTPN2/NR1H2/IL6	6
BP	GO:0034138	toll-like receptor 3 signaling pathway	6/2619	19/18670	0.04034	0.1512	0.1134	TNFAIP3/COLEC12/TNIP2/RFTN1/PTPN22/PELI1	6
BP	GO:0060438	trachea development	6/2619	19/18670	0.04034	0.1512	0.1134	SOX9/MAPK3/BMP4/LEF1/FOXF1/HOXA5	6
BP	GO:0071243	cellular response to arsenic-containing substance	6/2619	19/18670	0.04034	0.1512	0.1134	ATF3/UROS/DAXX/HNRNPA1/MKNK2/ATF4	6
BP	GO:0090201	negative regulation of release of cytochrome c from mitochondria	6/2619	19/18670	0.04034	0.1512	0.1134	CLU/HGF/NOL3/GPX1/IGF1/PSMD10	6
BP	GO:1902074	response to salt	6/2619	19/18670	0.04034	0.1512	0.1134	DAXX/GHSR/ZNF16/HNRNPA1/HNRNPD/HSPA5	6
BP	GO:1902644	tertiary alcohol metabolic process	6/2619	19/18670	0.04034	0.1512	0.1134	AKR1B1/AKR1B10/CYP11A1/AKR7A2/AKR1C3/AKR1C4	6
BP	GO:1905939	regulation of gonad development	6/2619	19/18670	0.04034	0.1512	0.1134	NUPR1/SOX9/SEMA3A/INSR/ZFPM2/GDF9	6
BP	GO:1901991	negative regulation of mitotic cell cycle phase transition	45/2619	248/18670	0.04035	0.1512	0.1134	TOPBP1/BTN2A2/SKP1/NBN/RFWD3/CRADD/CHEK2/PSMB9/EZH2/ATM/CDKN2C/CDK4/TPR/CTDSPL/BUB1B/LCMT1/PSMC2/USP47/DONSON/TPRA1/NDC80/MYO16/PLK2/PSMB6/CCNB1/PSMC3/TAOK1/PML/CDC20/AURKB/PSMD8/PSMB5/ZFP36L2/PSMD10/TAOK3/GTSE1/CDK1/CDKN1A/WEE1/EP300/KANK2/HMGA2/CENPF/RBL2/FBXO5	45
BP	GO:0061333	renal tubule morphogenesis	17/2619	78/18670	0.04041	0.1512	0.1134	SIX1/HOXA11/SOX9/PGF/CTNNBIP1/BMP4/WNT11/KLHL3/LAMA5/AGT/SIX2/MYC/VEGFA/MAGED1/LGR5/COL4A1/SMO	17
BP	GO:0090398	cellular senescence	17/2619	78/18670	0.04041	0.1512	0.1134	SMC6/HLA-G/ING2/SMC5/PLK2/PML/NAMPT/PLA2R1/MAP3K3/KAT6A/ID2/CDKN1A/KRAS/HMGA1/HMGA2/TWIST1/FBXO5	17
BP	GO:0009409	response to cold	12/2619	50/18670	0.04054	0.1512	0.1134	NFKBIA/CXCL10/CIRBP/PPARG/ADRB2/NFE2L1/DNAJC3/LPL/PRKAA1/HSPA2/ATP2B1/RNF34	12
BP	GO:0032608	interferon-beta production	12/2619	50/18670	0.04054	0.1512	0.1134	IRF1/RIPK2/TBK1/POLR3C/REL/NMI/IRF3/RELB/TRAF3/PPM1B/RIOK3/TLR8	12
BP	GO:0072698	protein localization to microtubule cytoskeleton	12/2619	50/18670	0.04054	0.1512	0.1134	GSK3B/C2CD3/MAPRE3/SPAG5/BBS4/DCTN2/PCM1/GOLGB1/KIAA0753/SNX10/MAPRE2/NUP62	12
BP	GO:0003382	epithelial cell morphogenesis	9/2619	34/18670	0.04057	0.1512	0.1134	AR/NOTCH4/STC1/PECAM1/BCL11B/FAT1/TNMD/ROCK1/SIPA1L3	9
BP	GO:0007094	mitotic spindle assembly checkpoint	9/2619	34/18670	0.04057	0.1512	0.1134	ATM/TPR/BUB1B/LCMT1/NDC80/CCNB1/CDC20/AURKB/CENPF	9
BP	GO:0009164	nucleoside catabolic process	9/2619	34/18670	0.04057	0.1512	0.1134	ENTPD4/ADA/APOBEC3C/DPYS/TYMP/PNP/APOBEC3B/AHCY/NT5E	9
BP	GO:0031577	spindle checkpoint	9/2619	34/18670	0.04057	0.1512	0.1134	ATM/TPR/BUB1B/LCMT1/NDC80/CCNB1/CDC20/AURKB/CENPF	9
BP	GO:0042533	tumor necrosis factor biosynthetic process	9/2619	34/18670	0.04057	0.1512	0.1134	JAK2/UBE2J1/CX3CR1/HSPB1/IFNG/GHSR/TYROBP/MAPKAPK2/CCR2	9
BP	GO:0042534	regulation of tumor necrosis factor biosynthetic process	9/2619	34/18670	0.04057	0.1512	0.1134	JAK2/UBE2J1/CX3CR1/HSPB1/IFNG/GHSR/TYROBP/MAPKAPK2/CCR2	9
BP	GO:0071173	spindle assembly checkpoint	9/2619	34/18670	0.04057	0.1512	0.1134	ATM/TPR/BUB1B/LCMT1/NDC80/CCNB1/CDC20/AURKB/CENPF	9
BP	GO:0071174	mitotic spindle checkpoint	9/2619	34/18670	0.04057	0.1512	0.1134	ATM/TPR/BUB1B/LCMT1/NDC80/CCNB1/CDC20/AURKB/CENPF	9
BP	GO:1901988	negative regulation of cell cycle phase transition	48/2619	267/18670	0.0406	0.1512	0.1134	TOPBP1/BTN2A2/SKP1/NBN/RFWD3/CRADD/CHEK2/PSMB9/CHEK1/EZH2/ATM/CDKN2C/CDK4/TPR/CTDSPL/BUB1B/LCMT1/PSMC2/USP47/DONSON/TPRA1/NDC80/MYO16/PLK2/PSMB6/CCNB1/PSMC3/TAOK1/PML/CDC20/AURKB/PSMD8/DTL/PSMB5/ZFP36L2/PSMD10/TAOK3/BABAM1/GTSE1/CDK1/CDKN1A/WEE1/EP300/KANK2/HMGA2/CENPF/RBL2/FBXO5	48
BP	GO:0045471	response to ethanol	25/2619	125/18670	0.04061	0.1512	0.1134	PEMT/USP46/SDF4/RBP4/BAD/NQO1/BIRC2/PENK/HPGD/GGH/CAT/CD27/OXCT1/ITPR2/RGS4/CRHBP/RPL10A/SOD1/PRKAA1/TYMS/CDK1/CCL7/PTK2B/ACTR2/TH	25
BP	GO:0060537	muscle tissue development	70/2619	408/18670	0.04122	0.1534	0.1151	PITX1/SIX1/SIK1/NUPR1/NOTCH1/JARID2/EYA2/SOX9/IGFBP5/SGCG/MYL6B/SMAD3/CFLAR/CBY1/SGCB/FOXC1/RBP4/PIM1/ATF3/MYOM2/RXRA/BMP4/FGF20/LEF1/MED1/GPX1/MYL3/NEBL/TAZ/S1PR1/ARID1A/MAML1/CCNT2/RGS4/MAFF/ZFPM2/AGT/MAPK11/CTDP1/IGF1/TBX5/CCNB1/EGR1/FHOD3/RBPJ/SORBS2/VEGFA/PIN1/PPP3CA/HOXD9/PRKAA1/HLF/AKAP13/CREB1/CDK1/ID2/LUC7L/CXADR/SAP30/ERBB4/EP300/COL3A1/FZD7/SMO/MYH10/CENPF/GTF3C5/TENM4/TWIST1/NR1D2	70
BP	GO:0050886	endocrine process	18/2619	84/18670	0.04148	0.1541	0.1156	CPA3/TACR2/HSD11B2/CMA1/RAB11FIP1/F2R/AGT/CRHBP/NOS3/TMF1/TAC1/GDF9/CTSG/GAL/CRY1/INHBB/KRAS/CORIN	18
BP	GO:0030705	cytoskeleton-dependent intracellular transport	34/2619	180/18670	0.04158	0.1541	0.1156	MREG/IFT46/RASGRP1/ARL3/NDE1/UCHL1/RPGR/SYNE2/SPG11/CCDC88C/IFT52/DYNLRB1/BLOC1S1/TRAK1/HSPB1/KIF5C/PCM1/DYNC1I1/VAMP7/KIF4A/TNPO1/CLUAP1/DYNC1H1/IFT140/UBB/SFPQ/PEX14/SOD1/SPAST/HIF1A/HOOK2/IFT22/TRIM58/DYNC2LI1	34
BP	GO:0031114	regulation of microtubule depolymerization	8/2619	29/18670	0.04162	0.1541	0.1156	STMN2/FGF13/ARHGEF2/TAOK1/CLASP1/SPAST/KATNB1/CIB1	8
BP	GO:0035666	TRIF-dependent toll-like receptor signaling pathway	8/2619	29/18670	0.04162	0.1541	0.1156	BIRC3/TBK1/BIRC2/IRF3/CHUK/UBB/TRAF3/IKBKG	8
BP	GO:0044788	modulation by host of viral process	8/2619	29/18670	0.04162	0.1541	0.1156	APOE/FBXL2/PC/CCL8/YTHDC2/CCNK/PPIB/VAPA	8
BP	GO:0060142	regulation of syncytium formation by plasma membrane fusion	8/2619	29/18670	0.04162	0.1541	0.1156	CXCL9/CXCL10/TREM2/IL4R/CFLAR/TYROBP/CAMK1/TNFSF14	8
BP	GO:0072538	T-helper 17 type immune response	8/2619	29/18670	0.04162	0.1541	0.1156	IL27RA/MALT1/RORA/RC3H2/LY9/IL6/PRKCQ/BATF	8
BP	GO:0007141	male meiosis I	7/2619	24/18670	0.04177	0.1541	0.1156	MYBL1/UBR2/ING2/BRCA2/UBB/RAD51C/HSPA2	7
BP	GO:0009309	amine biosynthetic process	7/2619	24/18670	0.04177	0.1541	0.1156	AGMAT/SMS/MOXD1/HDC/SULT1A2/SRM/OAZ3	7
BP	GO:0032878	regulation of establishment or maintenance of cell polarity	7/2619	24/18670	0.04177	0.1541	0.1156	ROCK1/KRIT1/CDH5/LLGL2/PTK2B/RAP1B/ARFGEF1	7
BP	GO:0046475	glycerophospholipid catabolic process	7/2619	24/18670	0.04177	0.1541	0.1156	PNPLA6/LIPC/PLA2G15/PRDX6/GDE1/PLA2G4C/APOC1	7
BP	GO:0046697	decidualization	7/2619	24/18670	0.04177	0.1541	0.1156	PTN/MAPK3/BSG/STC1/GHSR/STC2/EPOR	7
BP	GO:0090023	positive regulation of neutrophil chemotaxis	7/2619	24/18670	0.04177	0.1541	0.1156	DYSF/THBS4/RAC2/XCL1/CCR7/CXCR2/CXCL8	7
BP	GO:1902914	regulation of protein polyubiquitination	7/2619	24/18670	0.04177	0.1541	0.1156	DYSF/TRIP12/NMI/BIRC2/PTPN22/NOD2/UBR5	7
BP	GO:2000209	regulation of anoikis	7/2619	24/18670	0.04177	0.1541	0.1156	SIK1/NOTCH1/CHEK2/ITGA5/NTRK2/MCL1/PIK3CA	7
BP	GO:0043967	histone H4 acetylation	15/2619	67/18670	0.04222	0.1555	0.1166	TADA3/MSL3/LEF1/MSL2/ARRB1/AUTS2/TRRAP/NAA50/BRCA2/RUVBL2/KAT6A/KAT5/OGT/EP300/MORF4L1	15
BP	GO:0046365	monosaccharide catabolic process	15/2619	67/18670	0.04222	0.1555	0.1166	CRYL1/RBKS/ALDH1A1/BAD/PGM1/SORD/FUT1/ENO2/PFKM/LRP5/FUT8/ALDOC/FUT4/RPE/ADPGK	15
BP	GO:0060038	cardiac muscle cell proliferation	15/2619	67/18670	0.04222	0.1555	0.1166	NOTCH1/JARID2/FOXC1/RBP4/PIM1/RXRA/FGF20/ZFPM2/MAPK11/TBX5/CCNB1/RBPJ/CDK1/ERBB4/TENM4	15
BP	GO:0051480	regulation of cytosolic calcium ion concentration	62/2619	357/18670	0.04231	0.1556	0.1167	CXCL9/CXCL10/JAK2/FIS1/PLCG2/CXCL13/SNCA/SRI/SMAD3/CXCL11/GOT1/PTPRC/CD38/PTH1R/PRNP/CX3CR1/CCR5/NOL3/HTR2B/GNG3/KCNK3/PTGER4/GPER1/CXCR4/PTGFR/S1PR1/F2R/LCK/ITPR2/MCOLN3/ATP2B2/AGT/HCRT/HCRTR2/PML/FAM155A/XCL1/CD19/P2RX4/HMGB1/CALCR/PLCE1/CCR7/CXCR2/CACNB2/NMB/LIME1/CALB2/TPCN1/MCOLN1/LPAR2/TAC1/ATP2B4/CACNA1D/MS4A1/PTK2B/CCR2/GPR4/LETM1/ATP2B1/DDIT3/CXCR6	62
BP	GO:0001843	neural tube closure	19/2619	90/18670	0.04233	0.1556	0.1167	SFRP1/FOLR1/RALA/BMP4/SEMA4C/FZD3/BBS4/ARID1A/APAF1/DEAF1/ARHGAP35/GLMN/TMED2/PHACTR4/SETD2/BCL10/FZD6/TWIST1/FZD2	19
BP	GO:1901379	regulation of potassium ion transmembrane transport	19/2619	90/18670	0.04233	0.1556	0.1167	ATP1B1/TREM2/KCNQ1/NETO2/PRNP/BIN1/KLHL24/KCNJ2/ANK3/RGS4/CD63/VAMP2/KCNN2/AKAP9/CACNA1D/GAL/FLNA/NEDD4L/DPP6	19
BP	GO:0009743	response to carbohydrate	42/2619	230/18670	0.04238	0.1557	0.1168	FIS1/COLEC12/ERCC1/SRI/APOM/GOT1/PRKCB/MPC2/BAD/ANGPT2/EFNA5/CMA1/RMI1/GPER1/CAT/ARRB1/OXCT1/POLG/PTPRN2/LRP5/MAP4K4/EGR1/NAMPT/PCK2/TXN2/SLC2A5/ANO1/PPP3CA/VAMP2/LPL/HIF1A/PRKAA1/RAF1/RAB11B/TCF7L2/ENSA/XBP1/PTK2B/RAP1B/SERPINF1/TH/PIK3CA	42
BP	GO:0051321	meiotic cell cycle	45/2619	249/18670	0.04278	0.1571	0.1178	CDC25B/ZNF318/TUBG2/ERCC1/NBN/ASPM/KLHDC3/MYBL1/UBR2/ATM/PTTG1/RPA1/ACTR3/INSR/ING2/BUB1B/MNS1/RMI1/NCAPH/CKS2/NPR2/BRCA2/CDC20/EREG/ATRX/TUBGCP5/UBB/RAD51C/RAD50/YTHDC2/TOP2A/RAD1/SMC4/SMC1A/NDC1/C11orf80/CENPC/HSPA2/PIWIL2/ACTR2/TUBGCP2/RAD51B/PTTG2/DAZL/FBXO5	45
BP	GO:0042632	cholesterol homeostasis	20/2619	96/18670	0.04299	0.1577	0.1183	LIPC/SEC24A/APOM/RORA/EPHX2/MED13/APOE/CYP7B1/LRP5/NR1H2/ABCA2/COMMD9/NFE2L1/LPL/XBP1/LIMA1/FABP3/NPC1/NR5A2/TMEM97	20
BP	GO:0016574	histone ubiquitination	11/2619	45/18670	0.04314	0.1581	0.1186	SUZ12/SKP1/UBR2/TRIP12/PCGF1/DDB2/RYBP/RING1/UBR5/CDK9/WDR70	11
BP	GO:0032456	endocytic recycling	11/2619	45/18670	0.04314	0.1581	0.1186	MICALL1/ARL4C/MICALL2/EHD3/DENND1B/SNX17/CMTM6/RAB13/ACAP2/DENND1C/RAB11B	11
BP	GO:0001912	positive regulation of leukocyte mediated cytotoxicity	13/2619	56/18670	0.04333	0.1583	0.1188	HLA-C/RASGRP1/HLA-F/HLA-G/MICB/HLA-A/PTPRC/HLA-B/HLA-E/CRTAM/TYROBP/XCL1/ULBP2	13
BP	GO:0006749	glutathione metabolic process	13/2619	56/18670	0.04333	0.1583	0.1188	HPGDS/GSTA4/SLC7A11/GSTM4/GSTZ1/GPX1/GPX4/GSTM5/GSTM3/NFE2L1/SOD1/GGCT/GLO1	13
BP	GO:0044784	metaphase/anaphase transition of cell cycle	13/2619	56/18670	0.04333	0.1583	0.1188	ATM/DLGAP5/TPR/BUB1B/LCMT1/NDC80/CENPE/CCNB1/CDC20/AURKB/TACC3/CENPF/FBXO5	13
BP	GO:0070936	protein K48-linked ubiquitination	13/2619	56/18670	0.04333	0.1583	0.1188	TNFAIP3/UBE2D4/NMI/BIRC2/KLHL3/PELI1/UBE2E3/RNF187/TRIM32/UBR5/FBXO38/RNF34/NEDD4L	13
BP	GO:0072528	pyrimidine-containing compound biosynthetic process	13/2619	56/18670	0.04333	0.1583	0.1188	NME4/TK2/NME7/AGPAT1/NME5/AGPAT5/NME3/TYMP/CPS1/DCTD/CTPS1/TYMS/PRPS1	13
BP	GO:0001823	mesonephros development	21/2619	102/18670	0.04348	0.1584	0.1188	SIX1/HOXA11/SFRP1/SOX9/CRLF1/PGF/SMAD3/FOXC1/SDC1/CTNNBIP1/BMP4/WNT11/LAMA5/CAT/OSR2/AGT/SIX2/MYC/VEGFA/MAGED1/SMO	21
BP	GO:0006900	vesicle budding from membrane	21/2619	102/18670	0.04348	0.1584	0.1188	FOLR1/SEC24A/SERPINA1/PPP6R3/AP2M1/SEC22B/SEC13/F8/TRAPPC2L/CNIH1/TRAPPC10/PRKCI/SEC16A/TMED2/TMED9/TMED10/ANKRD28/GOLPH3/VAPA/NAPA/CD59	21
BP	GO:0021549	cerebellum development	21/2619	102/18670	0.04348	0.1584	0.1188	PTN/RORA/FOXC1/SDF4/EZH2/B4GALT2/AGTPBP1/ZNF365/SEMA4C/HERC1/NAGLU/MYO16/CD3E/EN1/PTBP2/UQCRQ/HNRNPD/SEZ6L/SMO/HSPA5/MYH10	21
BP	GO:0035335	peptidyl-tyrosine dephosphorylation	21/2619	102/18670	0.04348	0.1584	0.1188	PTPRE/CDC25B/DUSP5/EYA2/DUSP6/MTMR4/PTPRF/PTPRC/PTPN7/RNGTT/MTMR6/PTPN22/CDC14A/PTPN2/SSH3/PTPRN2/MTMR1/DUSP2/PTPRK/ACP1/PTPRH	21
BP	GO:0071774	response to fibroblast growth factor	29/2619	150/18670	0.04348	0.1584	0.1188	SFRP1/SETX/CCL5/PRKD2/MAPK3/CXCL13/SNCA/POLR2J/POLR2I/POLR2L/POLR2E/POLR2F/FGF20/FIBP/SHOC2/POLR2C/CD44/POSTN/TIA1/FGF18/SHCBP1/POLR2G/CPS1/GALNT3/HNRNPA1/ZFP36L2/NCBP2/CXCL8/FGF5	29
BP	GO:0033555	multicellular organismal response to stress	16/2619	73/18670	0.04377	0.1593	0.1195	GCH1/BRINP1/THBS4/USP46/IDO1/COMT/APOE/PENK/NTRK1/TSPO/DEAF1/P2RX4/PPP3CA/SCN9A/TAC1/VDAC3	16
BP	GO:0006275	regulation of DNA replication	22/2619	108/18670	0.04382	0.1593	0.1195	CDC7/FBXW7/NBN/CCNA2/ATR/CHEK2/DNA2/EGFR/ZNF365/DBF4/DONSON/HCRT/BRCA2/EREG/ATRX/SMC1A/TIMELESS/CDK1/ID3/STOML2/RFC2/FBXO5	22
BP	GO:0071156	regulation of cell cycle arrest	22/2619	108/18670	0.04382	0.1593	0.1195	CRADD/CHEK2/ATM/CDK4/BIN1/GPER1/SETMAR/FOXM1/PLK2/INSM1/CCNB1/CRLF3/PML/CCNK/GTSE1/CDK1/ID2/CDKN1A/EP300/CDK9/HMGA2/RBL2	22
BP	GO:2000278	regulation of DNA biosynthetic process	22/2619	108/18670	0.04382	0.1593	0.1195	PARP3/PRKD2/MAPK3/HNRNPA2B1/ATR/TNKS2/HGF/ATM/PPARG/DCP2/MYC/PDGFB/HMBOX1/AURKB/HNRNPA1/PARP4/PRKCQ/PARM1/CDKN1A/PTK2B/HNRNPD/RFC2	22
BP	GO:0014706	striated muscle tissue development	67/2619	390/18670	0.04391	0.1595	0.1197	PITX1/SIX1/SIK1/NUPR1/NOTCH1/JARID2/EYA2/SGCG/MYL6B/SMAD3/CFLAR/CBY1/SGCB/FOXC1/RBP4/PIM1/ATF3/MYOM2/RXRA/BMP4/FGF20/LEF1/MED1/GPX1/MYL3/NEBL/TAZ/S1PR1/ARID1A/MAML1/CCNT2/RGS4/MAFF/ZFPM2/AGT/MAPK11/CTDP1/IGF1/TBX5/CCNB1/EGR1/FHOD3/RBPJ/SORBS2/VEGFA/PIN1/PPP3CA/HOXD9/PRKAA1/HLF/AKAP13/CREB1/CDK1/ID2/LUC7L/CXADR/SAP30/ERBB4/EP300/FZD7/SMO/MYH10/CENPF/GTF3C5/TENM4/TWIST1/NR1D2	67
BP	GO:0042552	myelination	26/2619	132/18670	0.04409	0.1599	0.1199	PTN/TNFRSF1B/CLU/HGF/ITGAX/TNFRSF21/PIKFYVE/NTRK2/ERBB2/NAB1/TYMP/PMP22/CXCR4/ADAM22/SERINC5/ID4/KLK8/MYOC/CST7/SOD1/ERCC2/FA2H/OLIG2/PLP1/PSAP/TENM4	26
BP	GO:0045598	regulation of fat cell differentiation	26/2619	132/18670	0.04409	0.1599	0.1199	WIF1/SFRP1/CEBPA/WNT5B/ENPP1/SMAD3/RORA/FTO/AAMDC/PPARG/GPER1/ID4/LMO3/ZFPM2/LRP5/ASXL2/IL6/SORT1/ZFP36L2/LPL/CREB1/ADIRF/ID2/XBP1/CEBPB/DDIT3	26
BP	GO:0072175	epithelial tube formation	26/2619	132/18670	0.04409	0.1599	0.1199	SIX1/SFRP1/FOLR1/TCTN1/SOX9/IFT52/RALA/BMP4/SEMA4C/FZD3/BBS4/ARID1A/APAF1/DEAF1/ARHGAP35/GLMN/TMED2/PHACTR4/HIF1A/SETD2/BCL10/CEP290/FZD6/PODXL/TWIST1/FZD2	26
BP	GO:0051283	negative regulation of sequestering of calcium ion	25/2619	126/18670	0.04416	0.1601	0.1201	CXCL9/CXCL10/PLCG2/SNCA/SRI/CXCL11/PTPRC/CCR5/NOL3/HTR2B/GPER1/F2R/LCK/ITPR2/MCOLN3/XCL1/CD19/PLCE1/CCR7/LIME1/TPCN1/MCOLN1/PTK2B/LETM1/DDIT3	25
BP	GO:0007611	learning or memory	46/2619	256/18670	0.04452	0.1613	0.121	BRINP1/PTN/LGMN/GPR88/TACR2/LILRB2/SLC7A11/FGF13/B4GALT2/EGFR/SYNJ1/ITGA5/COMT/PRNP/CX3CR1/NTRK2/APOE/INSR/NTF3/KIT/NTRK1/PLK2/GATM/AGT/KLK8/CRHBP/TMOD2/GHSR/ADCY1/EN1/GM2A/ATP8A1/DEAF1/NRGN/HIF1A/TAC1/CREB1/VDAC3/GALR3/EP300/KRAS/CEBPB/SERPINF1/ACTR2/BDNF/TH	46
BP	GO:0001570	vasculogenesis	17/2619	79/18670	0.04501	0.1628	0.1221	NOTCH1/FBXW7/TMEM100/NTRK2/TIE1/FOXF1/ZFPM2/TBX5/KDR/RASIP1/VEGFA/GLMN/EMP2/HAS2/SETD2/SGPL1/SMO	17
BP	GO:0003151	outflow tract morphogenesis	17/2619	79/18670	0.04501	0.1628	0.1221	SIX1/NOTCH1/FOLR1/NIPBL/DHRS3/FOXC1/BMP4/WNT11/ZFPM2/RBPJ/NPY1R/VEGFA/PLXND1/HIF1A/ATF2/TWIST1/FZD2	17
BP	GO:0043536	positive regulation of blood vessel endothelial cell migration	17/2619	79/18670	0.04501	0.1628	0.1221	PRKD2/ANGPT1/ADAM17/CD40/HSPB1/PLK2/NOS3/FGF18/KDR/PDGFB/VEGFA/P2RX4/HMGB1/MAP3K3/HIF1A/CIB1/STAT5A	17
BP	GO:0032200	telomere organization	33/2619	175/18670	0.04506	0.1629	0.1222	SMC6/PARP3/DCLRE1C/MAPK3/ERCC1/HNRNPA2B1/NBN/POLD2/ATR/TNKS2/ATM/DNA2/ZNF365/NHP2/RPA1/RPA3/POLD4/SMC5/DCP2/MYC/BRCA2/PML/ATRX/HMBOX1/AURKB/HNRNPA1/RAD51C/PRKCQ/RAD50/NABP2/WRN/HNRNPD/RFC2	33
BP	GO:0032386	regulation of intracellular transport	72/2619	423/18670	0.04515	0.1631	0.1223	ZIC1/LCP1/GAS1/ECT2/FIS1/FBXW7/MAPK3/ANGPT1/RIMS3/SMAD3/PREPL/MICALL2/PRKCB/IL4R/BARD1/NUP153/UBE2J1/PRNP/PFN2/PINK1/GSK3B/TPR/BMP4/ERBB2/TMEM30A/SPAG5/ANK3/FGR/CRYAB/FOXF1/CD81/PPP1R12A/IFNG/PRR5L/PCM1/YIPF5/RAC2/SEC16A/VAMP7/SCP2/ADCY1/ABCA2/DYNC1H1/FERMT1/ATG13/EDEM1/VAMP2/CACNB2/CAMK1/PRKAA1/SETD2/TARDBP/CIB1/CACNA1D/GTSE1/RAB11B/TCF7L2/NCBP2/SYT1/CEP290/NUCB1/UBL5/FLNA/SYN1/UBR5/RAP1B/IL13RA2/SMO/NAPA/NUP62/DNAJC13/TRIM58	72
BP	GO:0031640	killing of cells of other organism	14/2619	62/18670	0.04559	0.1644	0.1233	APOL1/BAD/PRF1/ELANE/TUSC2/IFNG/GNLY/DEFA6/HMGN2/CCL13/MBL2/CTSG/DEFA5/S100A12	14
BP	GO:0044364	disruption of cells of other organism	14/2619	62/18670	0.04559	0.1644	0.1233	APOL1/BAD/PRF1/ELANE/TUSC2/IFNG/GNLY/DEFA6/HMGN2/CCL13/MBL2/CTSG/DEFA5/S100A12	14
BP	GO:0046824	positive regulation of nucleocytoplasmic transport	14/2619	62/18670	0.04559	0.1644	0.1233	ZIC1/ECT2/SMAD3/GSK3B/TPR/IFNG/CAMK1/TARDBP/GTSE1/TCF7L2/NCBP2/FLNA/UBR5/SMO	14
BP	GO:0019835	cytolysis	10/2619	40/18670	0.04569	0.1645	0.1234	C7/GZMH/MICB/MMD/APOL1/RRAGA/PRF1/GZMB/GZMA/GSDMD	10
BP	GO:0045124	regulation of bone resorption	10/2619	40/18670	0.04569	0.1645	0.1234	TNFAIP3/TNFRSF11B/TFRC/CD38/EGFR/LTBP3/TNFRSF11A/S1PR1/IL6/CA2	10
BP	GO:0071548	response to dexamethasone	10/2619	40/18670	0.04569	0.1645	0.1234	CFLAR/DDIT4/EGFR/ASS1/GHSR/CPS1/PCK2/CASP9/USP8/SERPINF1	10
BP	GO:0045665	negative regulation of neuron differentiation	41/2619	225/18670	0.04576	0.1646	0.1235	NOTCH1/DIO3/SOX9/STMN2/GAK/SEMA4D/ASPM/SEMA4A/SPOCK1/CD38/SEMA3A/FGF13/ASAP1/ZNF365/APOE/GSK3B/SEMA4C/DGUOK/MED1/PMP22/YWHAH/ID4/CERS2/PLK2/KLK8/SEMA3F/MAP4K4/TLX2/ITM2C/EPHA4/NR2F1/SEMA3E/PPP3CA/CIB1/SIX3/NGFR/OLIG2/ID2/ID3/BCL11A/LRIG2	41
BP	GO:1905952	regulation of lipid localization	30/2619	157/18670	0.04646	0.1666	0.125	NFKBIA/FBXW7/FTO/EGF/TNFRSF11A/APOE/MEST/OSBPL8/HNRNPK/PPARG/PTPN2/NFKB1/APOC1/AGT/TSPO/NR1H2/IL6/SCP2/ABCA2/ATP8A1/P2RX4/PLA2R1/NCOR1/LPL/TMF1/TAC1/GDF9/GAL/CRY1/FABP3	30
BP	GO:0002712	regulation of B cell mediated immunity	12/2619	51/18670	0.0465	0.1666	0.125	PARP3/TFRC/IL27RA/PTPRC/THOC1/HLA-E/CD28/CD40/CR1/XCL1/TNFSF4/C4BPB	12
BP	GO:0002889	regulation of immunoglobulin mediated immune response	12/2619	51/18670	0.0465	0.1666	0.125	PARP3/TFRC/IL27RA/PTPRC/THOC1/HLA-E/CD28/CD40/CR1/XCL1/TNFSF4/C4BPB	12
BP	GO:0006213	pyrimidine nucleoside metabolic process	12/2619	51/18670	0.0465	0.1666	0.125	NME4/TK2/NME7/ENTPD4/NME5/APOBEC3C/DPYS/NME3/TYMP/APOBEC3B/CTPS1/NT5E	12
BP	GO:0030071	regulation of mitotic metaphase/anaphase transition	12/2619	51/18670	0.0465	0.1666	0.125	ATM/DLGAP5/TPR/BUB1B/LCMT1/NDC80/CENPE/CCNB1/CDC20/AURKB/CENPF/FBXO5	12
BP	GO:0031050	dsRNA processing	12/2619	51/18670	0.0465	0.1666	0.125	ADAR/HNRNPA2B1/SMAD3/EGFR/PUM2/BMP4/PRKRA/PPP3CA/SNIP1/NCOR1/AGO3/TSN	12
BP	GO:0070918	production of small RNA involved in gene silencing by RNA	12/2619	51/18670	0.0465	0.1666	0.125	ADAR/HNRNPA2B1/SMAD3/EGFR/PUM2/BMP4/PRKRA/PPP3CA/SNIP1/NCOR1/AGO3/TSN	12
BP	GO:0060606	tube closure	19/2619	91/18670	0.04673	0.1674	0.1255	SFRP1/FOLR1/RALA/BMP4/SEMA4C/FZD3/BBS4/ARID1A/APAF1/DEAF1/ARHGAP35/GLMN/TMED2/PHACTR4/SETD2/BCL10/FZD6/TWIST1/FZD2	19
BP	GO:0072511	divalent inorganic cation transport	82/2619	489/18670	0.04677	0.1674	0.1256	CXCL9/DYSF/CXCL10/ATP1B1/CCL5/ATP2A3/PLCG2/SNCA/SRI/CXCL11/PRKCB/LILRB2/PTPRC/FGF14/LILRA2/EGF/ATP2C1/PRNP/ZDHHC17/STC1/BIN1/CCR5/NOL3/HTR2B/EHD3/KCNJ2/PHB/GPER1/CXCR4/TSPAN13/GPM6A/F2R/TMCO1/CCL8/IFNG/LCK/ITPR2/RGS4/MCOLN3/SLC39A8/ATP2B2/AGT/TSPO/NOS3/S100A1/HCRT/PML/FAM155A/PDGFB/XCL1/SLC11A1/CD19/P2RX4/CALCR/PLCE1/PKD2L1/CCR7/HOMER3/MICU1/PPP3CA/CACNB2/SLC39A14/ORAI3/REM1/LIME1/TPCN1/MCOLN1/ATP2B4/CACNA1D/TRPV2/LGALS3/HSPA2/CACNA2D3/MS4A1/YME1L1/PTK2B/STOML2/LETM1/CAMK2B/STC2/ATP2B1/DDIT3	82
BP	GO:0016236	macroautophagy	52/2619	295/18670	0.04681	0.1675	0.1256	NUPR1/MAPK3/RIPK2/VPS13C/GABARAPL1/TBK1/ATP6V0D1/GABARAPL2/VPS37C/UCHL1/PIKFYVE/UVRAG/PINK1/CAPNS1/RRAGA/PRKAG1/SEC22B/EXOC7/PRKAB1/PIK3C2B/CSNK2B/PIM2/POLDIP2/KLHL3/CHMP6/TCIRG1/ADRB2/ATG2B/VPS16/CHMP2A/KDR/TRAPPC8/UBQLN4/ATP6V0E2/ATG13/LAMTOR2/MLST8/OPTN/HIF1A/MCOLN1/PRKAA1/ATG4A/NOD1/IKBKG/RRAGD/ATG12/SESN1/NPC1/EXOC1/GABARAP/CLEC16A/PIK3CA	52
BP	GO:1903046	meiotic cell cycle process	35/2619	188/18670	0.04702	0.1681	0.1261	CDC25B/TUBG2/ERCC1/ASPM/KLHDC3/MYBL1/UBR2/ATM/PTTG1/ACTR3/ING2/BUB1B/RMI1/NCAPH/CKS2/BRCA2/CDC20/EREG/ATRX/UBB/RAD51C/RAD50/TOP2A/RAD1/SMC4/NDC1/C11orf80/CENPC/HSPA2/PIWIL2/ACTR2/RAD51B/PTTG2/DAZL/FBXO5	35
BP	GO:0000077	DNA damage checkpoint	28/2619	145/18670	0.04721	0.1687	0.1265	NBN/RFWD3/ATR/CRADD/CHEK2/CHEK1/ATM/THOC1/PEA15/DONSON/PLK2/CCNB1/TAOK1/PML/DTL/RAD1/TAOK3/BABAM1/GTSE1/CDK1/RAD9A/CDKN1A/ATF2/EP300/CEP63/CRY1/HMGA2/RBL2	28
BP	GO:0001657	ureteric bud development	20/2619	97/18670	0.04728	0.1687	0.1265	SIX1/HOXA11/SFRP1/SOX9/CRLF1/PGF/SMAD3/FOXC1/SDC1/CTNNBIP1/BMP4/WNT11/LAMA5/CAT/AGT/SIX2/MYC/VEGFA/MAGED1/SMO	20
BP	GO:0014020	primary neural tube formation	20/2619	97/18670	0.04728	0.1687	0.1265	SFRP1/FOLR1/RALA/BMP4/SEMA4C/FZD3/BBS4/ARID1A/APAF1/DEAF1/ARHGAP35/GLMN/TMED2/PHACTR4/HIF1A/SETD2/BCL10/FZD6/TWIST1/FZD2	20
BP	GO:0055092	sterol homeostasis	20/2619	97/18670	0.04728	0.1687	0.1265	LIPC/SEC24A/APOM/RORA/EPHX2/MED13/APOE/CYP7B1/LRP5/NR1H2/ABCA2/COMMD9/NFE2L1/LPL/XBP1/LIMA1/FABP3/NPC1/NR5A2/TMEM97	20
BP	GO:0016239	positive regulation of macroautophagy	15/2619	68/18670	0.0474	0.1687	0.1265	MAPK3/RIPK2/VPS13C/TBK1/UVRAG/PINK1/PIM2/ADRB2/KDR/OPTN/HIF1A/NOD1/IKBKG/SESN1/CLEC16A	15
BP	GO:0033866	nucleoside bisphosphate biosynthetic process	15/2619	68/18670	0.0474	0.1687	0.1265	PDK2/SNCA/MPC2/TECR/SLC25A1/ACSL5/GSTZ1/ACAT1/DLD/SCD5/PDK1/PDHB/PANK3/MPC1/PAPSS1	15
BP	GO:0034030	ribonucleoside bisphosphate biosynthetic process	15/2619	68/18670	0.0474	0.1687	0.1265	PDK2/SNCA/MPC2/TECR/SLC25A1/ACSL5/GSTZ1/ACAT1/DLD/SCD5/PDK1/PDHB/PANK3/MPC1/PAPSS1	15
BP	GO:0034033	purine nucleoside bisphosphate biosynthetic process	15/2619	68/18670	0.0474	0.1687	0.1265	PDK2/SNCA/MPC2/TECR/SLC25A1/ACSL5/GSTZ1/ACAT1/DLD/SCD5/PDK1/PDHB/PANK3/MPC1/PAPSS1	15
BP	GO:0033135	regulation of peptidyl-serine phosphorylation	27/2619	139/18670	0.04751	0.1687	0.1266	PRKD2/RIPK2/TBK1/ANGPT1/SNCA/HGF/DDIT4/EGFR/PFN2/NCK2/PINK1/NTRK2/NTF3/ARRB1/CD44/IFNG/IL6/VEGFA/CALCR/CAMK1/AKAP9/PRKAA1/ATP2B4/RAF1/GGNBP2/CAPRIN2/PIK3CA	27
BP	GO:0032091	negative regulation of protein binding	21/2619	103/18670	0.04766	0.1687	0.1266	MAPK3/SLPI/LRPAP1/PTPRF/TDG/CTNNBIP1/GSK3B/HFE/DDX11/LEF1/PIM2/ROCK1/ADRB2/PDGFB/AURKB/PIN1/CSNK1E/RUVBL2/PEX14/CAMK1/HSPA5	21
BP	GO:1902106	negative regulation of leukocyte differentiation	21/2619	103/18670	0.04766	0.1687	0.1266	SFRP1/IRF1/FBXW7/TCTA/HLA-G/IL4R/CTLA4/RUNX3/SOCS1/BMP4/ERBB2/PTPN2/RC3H2/TRIB1/HMGB3/MYC/TNFSF4/HMGB1/PRDX2/ID2/HOXA7	21
BP	GO:0002705	positive regulation of leukocyte mediated immunity	26/2619	133/18670	0.04775	0.1687	0.1266	HLA-C/RASGRP1/TFRC/MALT1/HLA-F/HLA-G/MICB/HLA-A/IL4R/PTPRC/HLA-B/HLA-E/CD28/CRTAM/FGR/CD40/CD81/VAMP7/IL6/XCL1/TNFSF4/NOD2/ULBP2/DDX1/DDX21/FBXO38	26
BP	GO:0072009	nephron epithelium development	22/2619	109/18670	0.0479	0.1687	0.1266	SIX1/HOXA11/NOTCH1/STAT1/SOX9/PGF/FOXC1/CTNNBIP1/PECAM1/BMP4/WNT11/MAGI2/KLHL3/LAMA5/ACAT1/AGT/SIX2/MYC/VEGFA/MAGED1/SMO/PODXL	22
BP	GO:0045727	positive regulation of translation	25/2619	127/18670	0.04792	0.1687	0.1266	CCL5/MAPK3/CIRBP/NCK2/PINK1/CDK4/UQCC1/RXRA/ERBB2/CD28/RMND1/LARP4/IL6/POLR2G/EIF2S3/COA3/DNAJC3/LARP6/EIF6/NGRN/PIWIL2/PTK2B/HNRNPD/PASK/DAZL	25
BP	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic	9/2619	35/18670	0.04806	0.1687	0.1266	LSM4/WDR61/EXOSC7/LSM3/DCP2/POLR2G/LSM5/EDC4/LSM2	9
BP	GO:0009262	deoxyribonucleotide metabolic process	9/2619	35/18670	0.04806	0.1687	0.1266	ADK/TDG/ADA/RRM2/SAMHD1/DGUOK/GUK1/DCTD/TYMS	9
BP	GO:0034142	toll-like receptor 4 signaling pathway	9/2619	35/18670	0.04806	0.1687	0.1266	TNFAIP3/NFKBIA/RIPK2/TRIL/LILRA2/TNIP3/PTPN22/PELI1/MFHAS1	9
BP	GO:0098801	regulation of renal system process	9/2619	35/18670	0.04806	0.1687	0.1266	COMT/STC1/CORO2B/F2R/AGT/PDGFB/EMP2/TAC1/CORIN	9
BP	GO:1905332	positive regulation of morphogenesis of an epithelium	9/2619	35/18670	0.04806	0.1687	0.1266	SIX1/AR/SOX9/ITGAX/BMP4/AGT/VEGFA/MAGED1/SMO	9
BP	GO:0006000	fructose metabolic process	5/2619	15/18670	0.04813	0.1687	0.1266	AKR1B1/ALDH1A1/SORD/PFKFB3/ALDOC	5
BP	GO:0006491	N-glycan processing	5/2619	15/18670	0.04813	0.1687	0.1266	GNPTAB/MAN1C1/MAN1B1/FUT8/ST8SIA2	5
BP	GO:0009209	pyrimidine ribonucleoside triphosphate biosynthetic process	5/2619	15/18670	0.04813	0.1687	0.1266	NME4/NME7/NME5/NME3/CTPS1	5
BP	GO:0009263	deoxyribonucleotide biosynthetic process	5/2619	15/18670	0.04813	0.1687	0.1266	ADK/RRM2/GUK1/DCTD/TYMS	5
BP	GO:0014856	skeletal muscle cell proliferation	5/2619	15/18670	0.04813	0.1687	0.1266	SIX1/JAK2/ANGPT1/CFLAR/PAXBP1	5
BP	GO:0035067	negative regulation of histone acetylation	5/2619	15/18670	0.04813	0.1687	0.1266	SNCA/SET/ZNF451/TAF7/TWIST1	5
BP	GO:0036445	neuronal stem cell division	5/2619	15/18670	0.04813	0.1687	0.1266	ASPM/FGF13/ARHGEF2/LEF1/DCT	5
BP	GO:0042754	negative regulation of circadian rhythm	5/2619	15/18670	0.04813	0.1687	0.1266	ADA/SFPQ/SUV39H2/CRY1/PIWIL2	5
BP	GO:0043101	purine-containing compound salvage	5/2619	15/18670	0.04813	0.1687	0.1266	ADK/ADA/DGUOK/PNP/AMPD3	5
BP	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly	5/2619	15/18670	0.04813	0.1687	0.1266	ATF7IP/PSMC2/PSMC3/HMGB1/CREB1	5
BP	GO:0046851	negative regulation of bone remodeling	5/2619	15/18670	0.04813	0.1687	0.1266	TNFAIP3/SFRP1/TNFRSF11B/CD38/IL6	5
BP	GO:0051883	killing of cells in other organism involved in symbiotic interaction	5/2619	15/18670	0.04813	0.1687	0.1266	BAD/ELANE/TUSC2/MBL2/CTSG	5
BP	GO:0055057	neuroblast division	5/2619	15/18670	0.04813	0.1687	0.1266	ASPM/FGF13/ARHGEF2/LEF1/DCT	5
BP	GO:0070571	negative regulation of neuron projection regeneration	5/2619	15/18670	0.04813	0.1687	0.1266	CERS2/KLK8/MAP4K4/EPHA4/LRIG2	5
BP	GO:0090192	regulation of glomerulus development	5/2619	15/18670	0.04813	0.1687	0.1266	CFLAR/BMP4/EGR1/PDGFB/IL6R	5
BP	GO:1901841	regulation of high voltage-gated calcium channel activity	5/2619	15/18670	0.04813	0.1687	0.1266	DYSF/SRI/FGF14/CACNB2/REM1	5
BP	GO:0006936	muscle contraction	62/2619	360/18670	0.04879	0.1708	0.1281	SGCA/DYSF/SPHK1/SCN1B/ATP1B1/SNTA1/FXYD1/TACR2/GAMT/MYL6B/SRI/KCNQ1/TMOD1/CD38/STC1/ADA/SSPN/MYOM2/KIT/BIN1/HSPB6/HTR2B/EHD3/ASPH/ROCK1/KCNJ2/MYL3/GPER1/CXCR4/TAZ/CRYAB/F2R/ADRB2/CHRNA3/AGT/CHUK/COMP/TMOD2/GHSR/HSBP1/P2RX4/PLCE1/MYL4/CHRNB1/CACNB2/KCNJ8/SOD1/KCNN2/GAA/MYH4/CTTN/ATP2B4/CACNA1D/ITGB5/NDUFS6/SNTB1/FLNA/ATP2B1/NEDD4L/VEGFB/PIK3CA/SORBS1	62
BP	GO:0006081	cellular aldehyde metabolic process	16/2619	74/18670	0.04884	0.1708	0.1281	ALDH7A1/RBKS/ALDH1A1/AKR7A3/PNPO/KDM3A/ESD/AKR7A2/ALDH9A1/GRHPR/AKR1C3/ALDH3A2/ALDH1A3/GLO1/RPE/ALDH3B1	16
BP	GO:0009064	glutamine family amino acid metabolic process	16/2619	74/18670	0.04884	0.1708	0.1281	FAH/DDAH1/GOT1/SLC7A11/AGMAT/ASRGL1/DDAH2/ASS1/NOS3/CPS1/OAT/ATP2B4/CTPS1/PYCR1/ALDH18A1/ASNS	16
BP	GO:0032677	regulation of interleukin-8 production	16/2619	74/18670	0.04884	0.1708	0.1281	PRKD2/PTPRC/SERPINE1/PTPN22/ARRB1/ELANE/F2R/TLR5/NOD2/CD58/CD2/FCN1/BCL10/MYD88/TLR8/DDIT3	16
BP	GO:0070373	negative regulation of ERK1 and ERK2 cascade	16/2619	74/18670	0.04884	0.1708	0.1281	GBP1/BTN2A2/DUSP6/TNIP1/PTPRC/ATF3/PHB/GPER1/PTPN2/ARRB1/NDRG2/LMO3/SIRT3/EIF3A/PIN1/FBLN1	16
BP	GO:0051055	negative regulation of lipid biosynthetic process	13/2619	57/18670	0.04919	0.1718	0.1288	SIK1/SPHK1/FBXW7/ERLIN2/APOE/GPER1/NFKB1/APOC1/WDTC1/AKR1C3/PDGFB/SOD1/PRKAA1	13
BP	GO:1903428	positive regulation of reactive oxygen species biosynthetic process	13/2619	57/18670	0.04919	0.1718	0.1288	JAK2/CLU/SMAD3/DDAH1/RAB27A/INSR/DDAH2/IFNG/AGT/ASS1/P2RX4/HBB/PTK2B	13
BP	GO:0048705	skeletal system morphogenesis	43/2619	239/18670	0.04974	0.1732	0.1299	SIX1/HOXA11/SFRP1/SCARA3/SOX9/MGP/NIPBL/SMAD3/DHRS3/FOXC1/NLE1/LTBP3/STC1/MDFI/BMP4/HOXB6/NAB1/CHAD/PLEKHA1/FGR/PEX7/PRKRA/OSR2/HOXA4/LRP5/COMP/FGF18/SIX2/MMP13/HOXB5/IFT140/IRX5/HOXD9/COL6A3/MBL2/HOXA5/HAS2/SETD2/HOXC11/SGPL1/HOXA7/TWIST1/SATB2	43
BP	GO:0010883	regulation of lipid storage	11/2619	46/18670	0.04978	0.1732	0.1299	NFKBIA/FBXW7/FTO/MEST/OSBPL8/PPARG/PTPN2/NFKB1/NR1H2/IL6/LPL	11
BP	GO:0014075	response to amine	11/2619	46/18670	0.04978	0.1732	0.1299	SLC18A2/UROS/RANBP2/RGS4/ASS1/CPS1/PPP3CA/SOD1/CDK1/HNMT/TH	11
BP	GO:0035196	production of miRNAs involved in gene silencing by miRNA	11/2619	46/18670	0.04978	0.1732	0.1299	ADAR/HNRNPA2B1/SMAD3/EGFR/PUM2/BMP4/PRKRA/PPP3CA/SNIP1/NCOR1/AGO3	11
BP	GO:0048512	circadian behavior	11/2619	46/18670	0.04978	0.1732	0.1299	ADA/NAGLU/EGR1/HCRTR2/PTGDS/AHCY/NCOR1/SIX3/ID2/TH/NR1D2	11
BP	GO:0071354	cellular response to interleukin-6	11/2619	46/18670	0.04978	0.1732	0.1299	CEBPA/STAT1/JAK2/PID1/JAK1/PHB/PTPN2/NFKB1/IL6/IL6R/SBNO2	11
BP	GO:1990928	response to amino acid starvation	11/2619	46/18670	0.04978	0.1732	0.1299	MAP3K5/DAP/MAPK3/FAS/SLC38A2/ATF3/RRAGA/RRAGD/CDKN1A/SESN1/ATF4	11
BP	GO:0001782	B cell homeostasis	8/2619	30/18670	0.05003	0.1735	0.1302	TNFAIP3/SH2B2/SOS1/DOCK10/ADA/RC3H2/HIF1A/BCL10	8
BP	GO:0044818	mitotic G2/M transition checkpoint	8/2619	30/18670	0.05003	0.1735	0.1302	TOPBP1/NBN/ATM/DONSON/TAOK1/TAOK3/CDK1/HMGA2	8
BP	GO:0048265	response to pain	8/2619	30/18670	0.05003	0.1735	0.1302	GCH1/THBS4/COMT/NTRK1/TSPO/P2RX4/SCN9A/TAC1	8
BP	GO:0071549	cellular response to dexamethasone stimulus	8/2619	30/18670	0.05003	0.1735	0.1302	CFLAR/DDIT4/EGFR/ASS1/PCK2/CASP9/USP8/SERPINF1	8
BP	GO:0090022	regulation of neutrophil chemotaxis	8/2619	30/18670	0.05003	0.1735	0.1302	DYSF/THBS4/RAC2/XCL1/CCR7/CXCR2/MPP1/CXCL8	8
BP	GO:0048738	cardiac muscle tissue development	42/2619	233/18670	0.05063	0.1755	0.1316	SIK1/NOTCH1/JARID2/SGCG/CBY1/SGCB/FOXC1/RBP4/PIM1/MYOM2/RXRA/BMP4/FGF20/MED1/MYL3/NEBL/TAZ/S1PR1/ARID1A/MAML1/RGS4/ZFPM2/AGT/MAPK11/CTDP1/IGF1/TBX5/CCNB1/FHOD3/RBPJ/SORBS2/VEGFA/PIN1/AKAP13/CREB1/CDK1/ID2/CXADR/ERBB4/FZD7/MYH10/TENM4	42
BP	GO:0042446	hormone biosynthetic process	18/2619	86/18670	0.05082	0.1755	0.1316	AKR1B1/DIO3/HSD11B2/HSD17B1/FDX1/CYP11A1/HFE/MED1/NFKB1/IFNG/TSPO/EGR1/AKR1C3/DIO2/DHCR7/HIF1A/HSD17B14/STC2	18
BP	GO:0048013	ephrin receptor signaling pathway	18/2619	86/18670	0.05082	0.1755	0.1316	ARPC1A/NCK2/CHN1/ACTR3/AP2M1/EFNA5/ROCK1/SIPA1L1/EPHB6/NTRK1/ARHGEF7/EFNB1/PSENEN/RBPJ/EPHA4/APH1B/APH1A/ACTR2	18
BP	GO:0002827	positive regulation of T-helper 1 type immune response	6/2619	20/18670	0.051	0.1755	0.1316	IL27RA/RIPK2/XCL1/SLC11A1/IL6R/CCR2	6
BP	GO:0008356	asymmetric cell division	6/2619	20/18670	0.051	0.1755	0.1316	ASPM/FGF13/ACTR3/ING2/ARHGEF2/ACTR2	6
BP	GO:0033630	positive regulation of cell adhesion mediated by integrin	6/2619	20/18670	0.051	0.1755	0.1316	CCL5/CXCL13/CD3E/FERMT1/CIB1/PODXL	6
BP	GO:0034104	negative regulation of tissue remodeling	6/2619	20/18670	0.051	0.1755	0.1316	TNFAIP3/SFRP1/TNFRSF11B/CD38/AGT/IL6	6
BP	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process	6/2619	20/18670	0.051	0.1755	0.1316	JAK2/HSPB1/IFNG/TYROBP/MAPKAPK2/CCR2	6
BP	GO:0050860	negative regulation of T cell receptor signaling pathway	6/2619	20/18670	0.051	0.1755	0.1316	GBP1/BTN2A2/PRNP/PTPN22/PTPN2/LGALS3	6
BP	GO:0051767	nitric-oxide synthase biosynthetic process	6/2619	20/18670	0.051	0.1755	0.1316	STAT1/JAK2/IFNG/KDR/NAMPT/NOD2	6
BP	GO:0051769	regulation of nitric-oxide synthase biosynthetic process	6/2619	20/18670	0.051	0.1755	0.1316	STAT1/JAK2/IFNG/KDR/NAMPT/NOD2	6
BP	GO:0071636	positive regulation of transforming growth factor beta production	6/2619	20/18670	0.051	0.1755	0.1316	CD200/SMAD3/WNT11/XCL1/CREB1/ATF2	6
BP	GO:1903978	regulation of microglial cell activation	6/2619	20/18670	0.051	0.1755	0.1316	SPHK1/TREM2/PTPRC/ATM/IL6/CST7	6
BP	GO:0090276	regulation of peptide hormone secretion	38/2619	208/18670	0.05106	0.1755	0.1316	SFRP1/JAK2/CCL5/RPH3AL/SRI/SLC25A4/MPC2/CD38/ARL2/RBP4/BAD/EGFR/HFE/EFNA5/GPER1/TCIRG1/ARRB1/HADH/OXCT1/IFNG/ITPR2/SIRT3/CRHBP/LRP5/MAP4K4/GHSR/ARL2BP/ABCC8/ANO1/PPP3CA/SSTR5/HIF1A/TARDBP/CACNA1D/TCF7L2/ENSA/INHBB/PASK	38
BP	GO:0002719	negative regulation of cytokine production involved in immune response	7/2619	25/18670	0.05122	0.1755	0.1316	IRAK3/ANGPT1/HLA-F/HFE/CD96/XCL1/CUEDC2	7
BP	GO:0007026	negative regulation of microtubule depolymerization	7/2619	25/18670	0.05122	0.1755	0.1316	STMN2/FGF13/ARHGEF2/TAOK1/CLASP1/KATNB1/CIB1	7
BP	GO:0045332	phospholipid translocation	7/2619	25/18670	0.05122	0.1755	0.1316	ATP8B1/TMEM30A/ABCC1/ATP8A1/ATP11B/ABCB1/ATP10A	7
BP	GO:0045662	negative regulation of myoblast differentiation	7/2619	25/18670	0.05122	0.1755	0.1316	CXCL10/NOTCH1/SOX9/MBNL3/BMP4/ID3/DDIT3	7
BP	GO:0050901	leukocyte tethering or rolling	7/2619	25/18670	0.05122	0.1755	0.1316	CX3CR1/SELE/ROCK1/ITGB7/ELANE/GOLPH3/CCR2	7
BP	GO:0051894	positive regulation of focal adhesion assembly	7/2619	25/18670	0.05122	0.1755	0.1316	SFRP1/SMAD3/ROCK1/KDR/MAP4K4/MYOC/VEGFA	7
BP	GO:0072677	eosinophil migration	7/2619	25/18670	0.05122	0.1755	0.1316	CCL5/PTGER4/CCL8/SCG2/CCL13/LGALS3/CCL7	7
BP	GO:1903859	regulation of dendrite extension	7/2619	25/18670	0.05122	0.1755	0.1316	ITSN2/CXCR4/SYT17/SYT1/CPNE6/BCL11A/NEDD4L	7
BP	GO:2000104	negative regulation of DNA-dependent DNA replication	7/2619	25/18670	0.05122	0.1755	0.1316	FBXW7/CHEK2/DONSON/BRCA2/SMC1A/TIMELESS/FBXO5	7
BP	GO:0006893	Golgi to plasma membrane transport	14/2619	63/18670	0.05133	0.1756	0.1317	ARL3/MACF1/PREPL/ANK3/BBS1/VAMP3/EXOC2/SEC16A/VAMP7/OPTN/VAMP2/GOLGA4/GOLPH3/EXOC1	14
BP	GO:0046637	regulation of alpha-beta T cell differentiation	14/2619	63/18670	0.05133	0.1756	0.1317	RIPK2/MALT1/IL4R/ADA/RUNX3/CD83/SOCS1/RC3H2/ZAP70/PNP/IFNG/PRDM1/TNFSF4/HMGB1	14
BP	GO:2000401	regulation of lymphocyte migration	14/2619	63/18670	0.05133	0.1756	0.1317	CXCL10/CD200/CCL5/IL27RA/CXCL13/STK10/ADAM17/TNFRSF14/XCL1/PADI2/TNFSF14/CCL7/PTK2B/CCR2	14
BP	GO:0006457	protein folding	41/2619	227/18670	0.05153	0.1762	0.1321	SPHK1/GAK/CLU/PFDN1/SIL1/PEX19/HSPH1/TTC1/CHORDC1/DNAJB14/PPIC/DNAJC1/HSPB6/DNAJA1/CSNK2B/RANBP2/CRYAB/CRTAP/HSPB1/NKTR/ATF6/NGLY1/HSPA6/TRAP1/SUCO/EMC2/GNB2/BAG1/RUVBL2/PPIE/PFDN5/LTBP4/DNAJC3/ERP44/PPIB/CCT6B/HSPA2/DNAJC24/NFYC/HSPA5/PPIH	41
BP	GO:0007272	ensheathment of neurons	26/2619	134/18670	0.05164	0.1763	0.1322	PTN/TNFRSF1B/CLU/HGF/ITGAX/TNFRSF21/PIKFYVE/NTRK2/ERBB2/NAB1/TYMP/PMP22/CXCR4/ADAM22/SERINC5/ID4/KLK8/MYOC/CST7/SOD1/ERCC2/FA2H/OLIG2/PLP1/PSAP/TENM4	26
BP	GO:0008366	axon ensheathment	26/2619	134/18670	0.05164	0.1763	0.1322	PTN/TNFRSF1B/CLU/HGF/ITGAX/TNFRSF21/PIKFYVE/NTRK2/ERBB2/NAB1/TYMP/PMP22/CXCR4/ADAM22/SERINC5/ID4/KLK8/MYOC/CST7/SOD1/ERCC2/FA2H/OLIG2/PLP1/PSAP/TENM4	26
BP	GO:0030038	contractile actin filament bundle assembly	20/2619	98/18670	0.05186	0.1766	0.1325	SFRP1/SMAD3/PFN2/CORO2B/LIMCH1/WNT11/ROCK1/BBS4/PTGER4/ARRB1/S1PR1/PPM1E/CLASP1/MYOC/ALMS1/NF2/TAC1/ITGB5/PTK2B/SORBS1	20
BP	GO:0043149	stress fiber assembly	20/2619	98/18670	0.05186	0.1766	0.1325	SFRP1/SMAD3/PFN2/CORO2B/LIMCH1/WNT11/ROCK1/BBS4/PTGER4/ARRB1/S1PR1/PPM1E/CLASP1/MYOC/ALMS1/NF2/TAC1/ITGB5/PTK2B/SORBS1	20
BP	GO:0050764	regulation of phagocytosis	20/2619	98/18670	0.05186	0.1766	0.1325	IL15RA/DYSF/SPHK1/TREM2/IL15/IL2RG/SYT11/RAB27A/PTPRC/MERTK/LMAN2/PPARG/FGR/IFNG/IL2RB/SLC11A1/HMGB1/C4BPB/SOD1/MBL2	20
BP	GO:0072163	mesonephric epithelium development	20/2619	98/18670	0.05186	0.1766	0.1325	SIX1/HOXA11/SFRP1/SOX9/CRLF1/PGF/SMAD3/FOXC1/SDC1/CTNNBIP1/BMP4/WNT11/LAMA5/CAT/AGT/SIX2/MYC/VEGFA/MAGED1/SMO	20
BP	GO:0072164	mesonephric tubule development	20/2619	98/18670	0.05186	0.1766	0.1325	SIX1/HOXA11/SFRP1/SOX9/CRLF1/PGF/SMAD3/FOXC1/SDC1/CTNNBIP1/BMP4/WNT11/LAMA5/CAT/AGT/SIX2/MYC/VEGFA/MAGED1/SMO	20
BP	GO:0051282	regulation of sequestering of calcium ion	25/2619	128/18670	0.05192	0.1767	0.1325	CXCL9/CXCL10/PLCG2/SNCA/SRI/CXCL11/PTPRC/CCR5/NOL3/HTR2B/GPER1/F2R/LCK/ITPR2/MCOLN3/XCL1/CD19/PLCE1/CCR7/LIME1/TPCN1/MCOLN1/PTK2B/LETM1/DDIT3	25
BP	GO:0043500	muscle adaptation	24/2619	122/18670	0.05212	0.1773	0.133	NOTCH1/JARID2/TNFRSF1B/IGFBP5/SMAD3/IL15/CFLAR/EZH2/GTF2IRD1/NOL3/ROCK1/RGS4/GATM/AGT/CTDP1/IGF1/NOS3/MYOC/PIN1/P2RX4/PPP3CA/ATP2B4/CDK9/CAMK2B	24
BP	GO:0021987	cerebral cortex development	23/2619	116/18670	0.05223	0.1776	0.1332	CDH2/NDE1/ASPM/BCL2A1/SEMA3A/SYNE2/FGF13/BAD/SLC38A2/EGFR/NTRK2/GSK3B/GNG12/BBS4/TACC2/HIF1A/TACC3/TMEM14B/COL3A1/FLNA/SMO/EMX2/TH	23
BP	GO:0000910	cytokinesis	32/2619	171/18670	0.0523	0.1777	0.1333	CDC25B/CETN2/ECT2/ARL3/UVRAG/RACGAP1/ACTR3/DCTN3/NUSAP1/CEP55/ROCK1/ANK3/BBS4/CDC14A/CHMP6/PRC1/PLK2/CHMP2A/KIF4A/BRCA2/AURKB/PIN1/USP8/SSTR5/SPAST/SETD2/CHMP1B/SON/KIF20A/ACTR2/MYH10/NUP62	32
BP	GO:0003007	heart morphogenesis	46/2619	259/18670	0.0526	0.1786	0.134	SIX1/NOTCH1/FOLR1/SOX9/NIPBL/SMAD3/TMEM100/DHRS3/FOXC1/SOS1/RBP4/SMARCD3/PIM1/IFT52/INSR/MYOM2/RXRA/BMP4/C2CD3/HTR2B/WNT11/MED1/MYL3/BBS4/S1PR1/MICAL2/FOXF1/RBM15/ZFPM2/NOS3/TBX5/RBPJ/NPY1R/VEGFA/PLXND1/CPE/TMED2/HIF1A/GAA/HAS2/ID2/ATF2/SMO/TH/TWIST1/FZD2	46
BP	GO:0006998	nuclear envelope organization	12/2619	52/18670	0.05303	0.1797	0.1348	PRKCB/GPER1/TOR1AIP1/BANF1/CCNB2/CHMP2A/CCNB1/ANKLE2/SPAST/TARDBP/CDK1/LPIN1	12
BP	GO:0032330	regulation of chondrocyte differentiation	12/2619	52/18670	0.05303	0.1797	0.1348	HOXA11/EFEMP1/SOX9/SMAD3/LTBP3/BMP4/GDF5/FGF18/SIX2/ZNF219/SCIN/MAF	12
BP	GO:0072132	mesenchyme morphogenesis	12/2619	52/18670	0.05303	0.1797	0.1348	NOTCH1/SOX9/SMAD3/TMEM100/FOXC1/WNT11/LEF1/FOXF1/NOS3/MYC/RBPJ/TWIST1	12
BP	GO:2000179	positive regulation of neural precursor cell proliferation	12/2619	52/18670	0.05303	0.1797	0.1348	NOTCH1/ASPM/EGF/SMARCD3/CX3CR1/FZD3/INSM1/VEGFA/DCT/HIF1A/FLNA/SMO	12
BP	GO:0030890	positive regulation of B cell proliferation	10/2619	41/18670	0.05312	0.1797	0.1348	CD320/TFRC/PTPRC/CD38/GPR183/ADA/CD40/CD81/PELI1/CDKN1A	10
BP	GO:0048286	lung alveolus development	10/2619	41/18670	0.05312	0.1797	0.1348	IGFBP5/SLC7A11/LTBP3/ADA/BMP4/RC3H2/FOXF1/TNS3/HOXA5/CREB1	10
BP	GO:0150077	regulation of neuroinflammatory response	10/2619	41/18670	0.05312	0.1797	0.1348	NUPR1/SPHK1/TREM2/CD200/TNFRSF1B/PTPRC/ATM/IGF1/IL6/CST7	10
BP	GO:0034250	positive regulation of cellular amide metabolic process	29/2619	153/18670	0.05419	0.1832	0.1374	CCL5/MAPK3/CLU/CIRBP/NCK2/PINK1/CDK4/UQCC1/RXRA/ERBB2/GSAP/CD28/IFNG/RMND1/LARP4/IL6/POLR2G/EIF2S3/EPHA4/COA3/DNAJC3/LARP6/EIF6/NGRN/PIWIL2/PTK2B/HNRNPD/PASK/DAZL	29
BP	GO:0001960	negative regulation of cytokine-mediated signaling pathway	16/2619	75/18670	0.05432	0.1832	0.1374	IRAK3/CCL5/ADAR/PTPRC/CARD8/SAMHD1/NOL3/PXDN/PPARG/PTPN2/NR1H2/IL6/MMP12/IL1RN/PADI2/SH2B3	16
BP	GO:0006353	DNA-templated transcription, termination	16/2619	75/18670	0.05432	0.1832	0.1374	SETX/POLR2L/POLR2E/POLR2F/PRMT5/TAF1D/CPSF7/POLR1B/CCNH/SCAF4/ERCC2/NCBP2/MNAT1/POLR1C/GTF2H3/CSTF2	16
BP	GO:0007422	peripheral nervous system development	16/2619	75/18670	0.05432	0.1832	0.1374	NTRK2/RUNX3/NTF3/ERBB2/NAB1/SLC5A3/PMP22/ADAM22/MYOC/GSTM3/ALDH3A2/HOXD9/SOD1/FA2H/CDK1/BDNF	16
BP	GO:0043242	negative regulation of protein complex disassembly	16/2619	75/18670	0.05432	0.1832	0.1374	IRAK3/STMN2/TMOD1/FGF13/CAPZA1/ARHGEF2/TAOK1/TMOD2/CLASP1/SCIN/UBQLN4/SCAF4/KATNB1/CIB1/LIMA1/CLEC16A	16
BP	GO:0046173	polyol biosynthetic process	16/2619	75/18670	0.05432	0.1832	0.1374	GCH1/AKR1B1/SPHK1/QDPR/PLCG2/SNCA/GOT1/PCBD1/PTH1R/ASAH1/GPER1/PCK2/PLCE1/PLCD1/ISYNA1/PTK2B	16
BP	GO:1990778	protein localization to cell periphery	54/2619	311/18670	0.05502	0.1854	0.1391	GBP1/ATP1B1/TREM2/AR/CDH2/GAK/ARL3/MACF1/PREPL/TNIK/TSPAN15/PID1/FGF13/MAP7/EGFR/PRNP/BSG/PRKCH/AP2M1/EHD3/VTI1B/ROCK1/ANK3/BBS1/GPER1/LAMA5/ADAM22/CD81/VAMP3/LIN7B/IFNG/PRKCI/RAB13/SEC16A/RAPGEF6/TMEM59/VAMP7/GHSR/EFR3A/TMED2/OPTN/VAMP2/CACNB2/EMP2/RANGRF/CIB1/GOLGA4/LGALS3/GOLPH3/RAB15/FLNA/AP4M1/SORBS1/DPP6	54
BP	GO:0016126	sterol biosynthetic process	17/2619	81/18670	0.05529	0.186	0.1395	CYB5R1/LBR/CH25H/PMVK/ERLIN2/APOE/SC5D/MBTPS1/DHCR24/DHCR7/KPNB1/SOD1/PRKAA1/CYB5R3/ACAA2/NFYC/MVK	17
BP	GO:0060761	negative regulation of response to cytokine stimulus	17/2619	81/18670	0.05529	0.186	0.1395	IRAK3/CCL5/ADAR/PTPRC/CARD8/MAPK7/SAMHD1/NOL3/PXDN/PPARG/PTPN2/NR1H2/IL6/MMP12/IL1RN/PADI2/SH2B3	17
BP	GO:1902930	regulation of alcohol biosynthetic process	17/2619	81/18670	0.05529	0.186	0.1395	SNCA/PMVK/ERLIN2/PTH1R/APOE/GPER1/SC5D/NFKB1/IFNG/MBTPS1/DHCR7/KPNB1/SOD1/PRKAA1/PTK2B/NFYC/MVK	17
BP	GO:2001021	negative regulation of response to DNA damage stimulus	17/2619	81/18670	0.05529	0.186	0.1395	SMCHD1/ERCC1/CLU/CHEK2/TRIP12/THOC1/ING2/USP47/CD44/TAF9B/UBQLN4/PSMD10/TRIM32/UBR5/HMGA2/TWIST1/FBXO5	17
BP	GO:0006949	syncytium formation	13/2619	58/18670	0.05558	0.1865	0.1399	CXCL9/CXCL10/PLEKHO1/TREM2/ERCC1/TCTA/IL4R/CFLAR/CD81/TYROBP/CAMK1/TNFSF14/SBNO2	13
BP	GO:0071385	cellular response to glucocorticoid stimulus	13/2619	58/18670	0.05558	0.1865	0.1399	CFLAR/DDIT4/EGFR/STC1/ASS1/PCK2/CASP9/USP8/SSTR5/ZFP36L2/AKAP13/SERPINF1/ATP2B1	13
BP	GO:1904589	regulation of protein import	13/2619	58/18670	0.05558	0.1865	0.1399	ZIC1/ECT2/ANGPT1/SMAD3/TPR/BMP4/IFNG/FERMT1/TARDBP/FLNA/UBR5/SMO/NUP62	13
BP	GO:0034329	cell junction assembly	43/2619	241/18670	0.0557	0.1865	0.1399	SFRP1/CDH2/ECT2/TRIP6/MACF1/SMAD3/MICALL2/ARL2/ITGA5/PRKCH/CORO2B/LIMCH1/PECAM1/CAPZA1/EFNA5/WNT11/ROCK1/LAMA5/FERMT2/CDH5/KRT14/ARHGEF7/AGT/PRKCI/RAB13/KDR/MAP4K4/CLASP1/CD151/MYOC/MTDH/VEGFA/TNS1/PTPRK/CDH12/LSR/TLN2/CTTN/ACTN1/FLNA/PTK2B/RAP1B/SORBS1	43
BP	GO:0140013	meiotic nuclear division	32/2619	172/18670	0.05593	0.1865	0.1399	CDC25B/ASPM/KLHDC3/MYBL1/UBR2/ATM/PTTG1/ACTR3/ING2/BUB1B/RMI1/NCAPH/CKS2/BRCA2/CDC20/EREG/UBB/RAD51C/RAD50/TOP2A/RAD1/SMC4/NDC1/C11orf80/CENPC/HSPA2/PIWIL2/ACTR2/RAD51B/PTTG2/DAZL/FBXO5	32
BP	GO:0002604	regulation of dendritic cell antigen processing and presentation	4/2619	11/18670	0.0563	0.1865	0.1399	SLC11A1/CCR7/NOD2/NOD1	4
BP	GO:0003093	regulation of glomerular filtration	4/2619	11/18670	0.0563	0.1865	0.1399	CORO2B/F2R/PDGFB/EMP2	4
BP	GO:0003264	regulation of cardioblast proliferation	4/2619	11/18670	0.0563	0.1865	0.1399	SIX1/NOTCH1/PIM1/TBX5	4
BP	GO:0006857	oligopeptide transport	4/2619	11/18670	0.0563	0.1865	0.1399	SLC7A11/ABCC1/CA2/SLC15A2	4
BP	GO:0033089	positive regulation of T cell differentiation in thymus	4/2619	11/18670	0.0563	0.1865	0.1399	RASGRP1/IL7R/ADA/VNN1	4
BP	GO:0033327	Leydig cell differentiation	4/2619	11/18670	0.0563	0.1865	0.1399	AR/PLEKHA1/TMF1/SGPL1	4
BP	GO:0035404	histone-serine phosphorylation	4/2619	11/18670	0.0563	0.1865	0.1399	CCNB1/AURKB/PRKAA1/HMGA2	4
BP	GO:0035747	natural killer cell chemotaxis	4/2619	11/18670	0.0563	0.1865	0.1399	CCL5/XCL1/PIK3CD/CCL7	4
BP	GO:0045351	type I interferon biosynthetic process	4/2619	11/18670	0.0563	0.1865	0.1399	TBK1/NMI/IRF3/TLR8	4
BP	GO:0046051	UTP metabolic process	4/2619	11/18670	0.0563	0.1865	0.1399	NME4/NME7/NME5/NME3	4
BP	GO:0048672	positive regulation of collateral sprouting	4/2619	11/18670	0.0563	0.1865	0.1399	SEMA4D/EFNA5/RND2/BDNF	4
BP	GO:0060272	embryonic skeletal joint morphogenesis	4/2619	11/18670	0.0563	0.1865	0.1399	HOXA11/BMP4/OSR2/HOXC11	4
BP	GO:0060433	bronchus development	4/2619	11/18670	0.0563	0.1865	0.1399	SOX9/BMP4/ADAMTSL2/HOXA5	4
BP	GO:0060767	epithelial cell proliferation involved in prostate gland development	4/2619	11/18670	0.0563	0.1865	0.1399	NOTCH1/AR/SOX9/SERPINF1	4
BP	GO:0060837	blood vessel endothelial cell differentiation	4/2619	11/18670	0.0563	0.1865	0.1399	NOTCH1/TMEM100/RBPJ/FOXJ2	4
BP	GO:0061307	cardiac neural crest cell differentiation involved in heart development	4/2619	11/18670	0.0563	0.1865	0.1399	FOLR1/MAPK3/BMP4/TWIST1	4
BP	GO:0061308	cardiac neural crest cell development involved in heart development	4/2619	11/18670	0.0563	0.1865	0.1399	FOLR1/MAPK3/BMP4/TWIST1	4
BP	GO:0090193	positive regulation of glomerulus development	4/2619	11/18670	0.0563	0.1865	0.1399	CFLAR/EGR1/PDGFB/IL6R	4
BP	GO:0099624	atrial cardiac muscle cell membrane repolarization	4/2619	11/18670	0.0563	0.1865	0.1399	KCNQ1/KCNN2/CACNA1D/FLNA	4
BP	GO:1901096	regulation of autophagosome maturation	4/2619	11/18670	0.0563	0.1865	0.1399	UVRAG/ADRB2/UBQLN4/CLEC16A	4
BP	GO:1904321	response to forskolin	4/2619	11/18670	0.0563	0.1865	0.1399	FDX1/EFNA5/ADCY1/ADCY2	4
BP	GO:1904322	cellular response to forskolin	4/2619	11/18670	0.0563	0.1865	0.1399	FDX1/EFNA5/ADCY1/ADCY2	4
BP	GO:2000615	regulation of histone H3-K9 acetylation	4/2619	11/18670	0.0563	0.1865	0.1399	CHEK1/NAP1L2/ZNF451/PIWIL2	4
BP	GO:0010742	macrophage derived foam cell differentiation	9/2619	36/18670	0.05641	0.1865	0.1399	NFKBIA/STAT1/PRKCH/PPARG/NFKB1/AGT/NR1H2/LPL/EP300	9
BP	GO:0090077	foam cell differentiation	9/2619	36/18670	0.05641	0.1865	0.1399	NFKBIA/STAT1/PRKCH/PPARG/NFKB1/AGT/NR1H2/LPL/EP300	9
BP	GO:0090218	positive regulation of lipid kinase activity	9/2619	36/18670	0.05641	0.1865	0.1399	KIT/FGR/CD81/DGKZ/PDGFB/CD19/CCR7/NOD2/PTK2B	9
BP	GO:1902622	regulation of neutrophil migration	9/2619	36/18670	0.05641	0.1865	0.1399	SLAMF8/DYSF/THBS4/RAC2/XCL1/CCR7/CXCR2/MPP1/CXCL8	9
BP	GO:0051924	regulation of calcium ion transport	45/2619	254/18670	0.05662	0.1871	0.1404	CXCL9/DYSF/CXCL10/ATP1B1/CCL5/PLCG2/SNCA/SRI/CXCL11/LILRB2/FGF14/LILRA2/EGF/PRNP/STC1/BIN1/EHD3/GPER1/CXCR4/TSPAN13/F2R/RGS4/AGT/TSPO/NOS3/S100A1/HCRT/PML/PDGFB/XCL1/CD19/P2RX4/CALCR/HOMER3/CACNB2/REM1/LIME1/CACNA1D/TRPV2/LGALS3/HSPA2/PTK2B/CAMK2B/STC2/ATP2B1	45
BP	GO:0030838	positive regulation of actin filament polymerization	20/2619	99/18670	0.05676	0.1874	0.1406	IQGAP2/ACTR3B/ARPC1A/CDC42EP3/FCHSD2/PFN2/BAIAP2/NCK2/ACTR3/BIN1/MAGEL2/SCIN/CCR7/AP1AR/ARPC5L/CTTN/HIP1R/CYFIP1/PTK2B/ACTR2	20
BP	GO:0043648	dicarboxylic acid metabolic process	20/2619	99/18670	0.05676	0.1874	0.1406	FOLR1/MTHFD2/HAAO/GOT1/SLC7A11/ME2/DDO/PHYH/FOLR2/MDH2/ASS1/DLD/GRHPR/OAT/SUCLG1/ACOT8/MDH1/ALDH18A1/FH/TH	20
BP	GO:0006637	acyl-CoA metabolic process	21/2619	105/18670	0.05688	0.1875	0.1406	PDK2/SNCA/PMVK/ACSM5/MPC2/TECR/SLC25A1/ACOT13/ACSL5/HMGCL/GSTZ1/ACAT1/DLD/SCD5/PDK1/PDHB/SUCLG1/ACOT8/FAR2/MPC1/MVK	21
BP	GO:0035383	thioester metabolic process	21/2619	105/18670	0.05688	0.1875	0.1406	PDK2/SNCA/PMVK/ACSM5/MPC2/TECR/SLC25A1/ACOT13/ACSL5/HMGCL/GSTZ1/ACAT1/DLD/SCD5/PDK1/PDHB/SUCLG1/ACOT8/FAR2/MPC1/MVK	21
BP	GO:1902750	negative regulation of cell cycle G2/M phase transition	21/2619	105/18670	0.05688	0.1875	0.1406	TOPBP1/SKP1/NBN/PSMB9/CHEK1/ATM/PSMC2/USP47/DONSON/PSMB6/PSMC3/TAOK1/AURKB/PSMD8/DTL/PSMB5/PSMD10/TAOK3/BABAM1/CDK1/HMGA2	21
BP	GO:0007622	rhythmic behavior	11/2619	47/18670	0.05708	0.1875	0.1407	ADA/NAGLU/EGR1/HCRTR2/PTGDS/AHCY/NCOR1/SIX3/ID2/TH/NR1D2	11
BP	GO:0043303	mast cell degranulation	11/2619	47/18670	0.05708	0.1875	0.1407	RASGRP1/IL4R/S100A13/KIT/FGR/FOXF1/RAC2/VAMP7/LAT/PIK3CD/IL13RA2	11
BP	GO:0046638	positive regulation of alpha-beta T cell differentiation	11/2619	47/18670	0.05708	0.1875	0.1407	RIPK2/MALT1/IL4R/ADA/RUNX3/CD83/SOCS1/ZAP70/PNP/IFNG/TNFSF4	11
BP	GO:0070169	positive regulation of biomineral tissue development	11/2619	47/18670	0.05708	0.1875	0.1407	PTN/NELL1/SMAD3/ATRAID/BMP4/OSR2/ADRB2/CEBPB/ATF4/ATP2B1/FBXO5	11
BP	GO:0070849	response to epidermal growth factor	11/2619	47/18670	0.05708	0.1875	0.1407	SOX9/MAPK3/CFLAR/FOXC1/EGFR/BAIAP2/TPR/ERBB2/MED1/ZFP36L2/ERBB4	11
BP	GO:1901068	guanosine-containing compound metabolic process	11/2619	47/18670	0.05708	0.1875	0.1407	NME4/NME7/IMPDH2/NME5/MOCS2/DGUOK/NME3/GUK1/MPP1/TJP2/AMPD3	11
BP	GO:0043062	extracellular structure organization	71/2619	422/18670	0.0571	0.1875	0.1407	KAZALD1/TPSAB1/NOTCH1/NDNF/LCP1/TNFRSF1B/EFEMP2/TNFRSF11B/SOX9/ADAM19/LAMC3/CRISPLD2/LIPC/MFAP4/FBLN5/SMAD3/APOM/CFLAR/FOXC1/SDC1/ITGAX/ITGAL/ITGA5/ITGAE/BSG/TIMP2/SERPINE1/APOE/CAPNS1/PECAM1/HTRA1/ADAMTSL2/PLA2G7/CMA1/PXDN/ITGB7/LAMA5/CD44/ELANE/FOXF1/POSTN/APOC1/COL15A1/AGT/COMP/KDR/IL6/MMP13/HAPLN1/CLASP1/PDGFB/MMP12/ADAMTS3/FERMT1/COL5A3/COL6A3/LPL/SPOCK2/ERCC2/HAS2/MMP20/CTSG/ITGB5/MPV17/COL4A1/TIMP1/VCAN/FBLN1/COL3A1/COL4A2/ICAM3	71
BP	GO:0006826	iron ion transport	14/2619	64/18670	0.05756	0.1887	0.1415	TFRC/ATP6V0D1/IREB2/HFE/TCIRG1/IFNG/FTL/SLC11A1/ATP6V0E2/CP/SLC39A14/MCOLN1/RAB11B/SFXN1	14
BP	GO:0045669	positive regulation of osteoblast differentiation	14/2619	64/18670	0.05756	0.1887	0.1415	CEBPA/NELL1/ATRAID/HGF/CTNNBIP1/BMP4/LRP5/IGF1/IL6/SUCO/IL6R/CEBPB/GDPD2/FBXO5	14
BP	GO:0046834	lipid phosphorylation	14/2619	64/18670	0.05756	0.1887	0.1415	SPHK1/SOCS6/PIKFYVE/DGKA/SOCS1/PIK3C2B/DGKZ/PIK3CB/EFR3A/PIK3CD/PIK3C2G/CERK/CISH/PIK3CA	14
BP	GO:0050922	negative regulation of chemotaxis	14/2619	64/18670	0.05756	0.1887	0.1415	SLAMF8/NOTCH1/SEMA4D/CXCL13/SEMA4A/SEMA3A/ANGPT2/SEMA4C/PTPN2/ELANE/SEMA3F/NBL1/SEMA3E/PADI2	14
BP	GO:0034764	positive regulation of transmembrane transport	37/2619	204/18670	0.05864	0.1921	0.1441	CXCL9/CXCL10/ATP1B1/TREM2/FXYD1/PLCG2/SNCA/SRI/KCNQ1/CXCL11/FGF14/PINK1/INSR/OSBPL8/EHD3/KCNJ2/ANK3/GPER1/F2R/ADRB2/IFNG/AGT/PRKCI/IGF1/S100A1/XCL1/CD19/CA2/CALCR/CACNB2/ABCB1/AKAP9/GAL/HSPA2/FLNA/CCR2/SORBS1	37
BP	GO:0035148	tube formation	28/2619	148/18670	0.05884	0.1926	0.1445	SIX1/SFRP1/NOTCH1/FOLR1/TCTN1/SOX9/IFT52/RALA/BMP4/SEMA4C/FZD3/BBS4/ARID1A/APAF1/DEAF1/VEGFA/ARHGAP35/GLMN/TMED2/PHACTR4/HIF1A/SETD2/BCL10/CEP290/FZD6/PODXL/TWIST1/FZD2	28
BP	GO:0007204	positive regulation of cytosolic calcium ion concentration	55/2619	319/18670	0.05933	0.1936	0.1452	CXCL9/CXCL10/JAK2/FIS1/PLCG2/CXCL13/SNCA/SRI/CXCL11/PTPRC/CD38/PTH1R/PRNP/CX3CR1/CCR5/NOL3/HTR2B/GNG3/PTGER4/GPER1/CXCR4/PTGFR/S1PR1/F2R/LCK/ITPR2/MCOLN3/AGT/HCRT/PML/FAM155A/XCL1/CD19/P2RX4/HMGB1/CALCR/PLCE1/CCR7/CXCR2/CACNB2/NMB/LIME1/TPCN1/MCOLN1/LPAR2/TAC1/ATP2B4/CACNA1D/MS4A1/PTK2B/CCR2/GPR4/LETM1/DDIT3/CXCR6	55
BP	GO:0009394	2'-deoxyribonucleotide metabolic process	8/2619	31/18670	0.05945	0.1936	0.1452	ADK/TDG/ADA/SAMHD1/DGUOK/GUK1/DCTD/TYMS	8
BP	GO:0010458	exit from mitosis	8/2619	31/18670	0.05945	0.1936	0.1452	CDC14A/KNTC1/CTDP1/CHMP2A/CDKN1C/CLASP1/SPAST/SIRT7	8
BP	GO:0040018	positive regulation of multicellular organism growth	8/2619	31/18670	0.05945	0.1936	0.1452	DIO3/NIPBL/BBS4/GHSR/PPIB/CREB1/GHR/SMO	8
BP	GO:0042168	heme metabolic process	8/2619	31/18670	0.05945	0.1936	0.1452	FECH/BDH2/IREB2/UROD/UROS/TSPO/NFE2L1/CPOX	8
BP	GO:0050849	negative regulation of calcium-mediated signaling	8/2619	31/18670	0.05945	0.1936	0.1452	SRI/PRNP/GSK3B/MAPK7/DYRK2/HOMER3/ATP2B4/FHL2	8
BP	GO:0070306	lens fiber cell differentiation	8/2619	31/18670	0.05945	0.1936	0.1452	WNT5B/SMAD3/TMOD1/SLC7A11/CDKN1C/NF2/SIX3/MAF	8
BP	GO:1903393	positive regulation of adherens junction organization	8/2619	31/18670	0.05945	0.1936	0.1452	SFRP1/SMAD3/ROCK1/KDR/MAP4K4/MYOC/VEGFA/MAPRE2	8
BP	GO:2000406	positive regulation of T cell migration	8/2619	31/18670	0.05945	0.1936	0.1452	CXCL10/CCL5/CXCL13/ADAM17/TNFRSF14/XCL1/TNFSF14/CCR2	8
BP	GO:2000781	positive regulation of double-strand break repair	8/2619	31/18670	0.05945	0.1936	0.1452	PARP3/SMCHD1/DDX11/MMS19/SETMAR/FOXM1/TIMELESS/ACTR2	8
BP	GO:0034332	adherens junction organization	27/2619	142/18670	0.05948	0.1936	0.1452	SFRP1/CDH2/TRIP6/MACF1/SMAD3/CORO2B/LIMCH1/EFNA5/ROCK1/LAMA5/FERMT2/CDH5/ARHGEF7/KDR/MAP4K4/ANG/CLASP1/MYOC/VEGFA/CADM3/PTPRK/CDH12/CTTN/MAPRE2/ACTN1/PTK2B/SORBS1	27
BP	GO:0051604	protein maturation	67/2619	397/18670	0.05978	0.1945	0.1459	C7/LGMN/BIRC3/GAS1/CPA3/RIPK2/PROS1/CLU/PCSK1/SUSD4/TSPAN15/GLRX5/BAD/PRNP/IFT52/SERPINE1/CARD8/BIRC2/BIRC7/IGLV1-44/C2CD3/PCSK7/NOL3/SPON1/MMS19/CMA1/CPD/ASPH/CYFIP2/CFI/PHB/LIPT1/SPCS3/SEC11A/CD81/CR1/NAA16/COMP/NAA50/TMEM59/PSENEN/CD19/CPE/C4BPB/DHCR24/ADAMTS3/TASP1/CST7/IGLC1/CIDEB/OGT/IFI16/APH1B/CTSG/NFU1/METAP2/KAT2B/EP300/MIPEP/YME1L1/STOML2/APH1A/LMF1/CFP/CORIN/SRGN/CD59	67
BP	GO:0043624	cellular protein complex disassembly	39/2619	217/18670	0.06002	0.1952	0.1464	MICAL1/STMN2/GAK/SH3GL1/TMOD1/FGF13/KIF2A/SYNJ1/MTRF1/CAPZA1/ARHGEF2/ASPH/MRPL24/TRMT112/KIF18B/MICAL2/MRPL11/TAOK1/TMOD2/MRPL40/CLASP1/MRPL23/SCIN/MRPS33/PEX14/SPAST/KATNB1/MRPS28/MRPS17/CIB1/MRPS22/MRPS11/MRPL17/MRPL20/LIMA1/MRPL18/MRPS14/NAPA/MRPL4	39
BP	GO:0043331	response to dsRNA	12/2619	53/18670	0.06015	0.1952	0.1464	NFKBIA/IRAK3/MAPK3/RIPK2/COLEC12/RFTN1/IRF3/NFKB1/PELI1/DDX1/DDX21/RIOK3	12
BP	GO:0071320	cellular response to cAMP	12/2619	53/18670	0.06015	0.1952	0.1464	IGFBP5/KCNQ1/STC1/FDX1/PENK/ITPR2/ASS1/CRHBP/CPS1/AKAP9/RAP1B/HSPA5	12
BP	GO:1901185	negative regulation of ERBB signaling pathway	12/2619	53/18670	0.06015	0.1952	0.1464	LGMN/BTC/EGFR/EGF/ERBB2/PTPN2/CHMP6/CBLB/ARHGEF7/HBEGF/EREG/NUP62	12
BP	GO:1902099	regulation of metaphase/anaphase transition of cell cycle	12/2619	53/18670	0.06015	0.1952	0.1464	ATM/DLGAP5/TPR/BUB1B/LCMT1/NDC80/CENPE/CCNB1/CDC20/AURKB/CENPF/FBXO5	12
BP	GO:0046785	microtubule polymerization	16/2619	76/18670	0.0602	0.1952	0.1464	STMN2/TUBG2/SNCA/NDE1/ARL2/FGF13/MAPRE3/MAP7D3/DRG1/CDH5/CLASP1/TUBGCP5/AKAP9/RANGRF/TUBGCP2/FBXO5	16
BP	GO:0072088	nephron epithelium morphogenesis	16/2619	76/18670	0.0602	0.1952	0.1464	SIX1/HOXA11/STAT1/SOX9/PGF/CTNNBIP1/BMP4/WNT11/KLHL3/LAMA5/AGT/SIX2/MYC/VEGFA/MAGED1/SMO	16
BP	GO:0044272	sulfur compound biosynthetic process	35/2619	192/18670	0.06068	0.1966	0.1475	HPGDS/CBS/GSTA4/PDK2/UST/BHMT2/ANGPT1/SNCA/MPC2/SLC7A11/TECR/SLC25A1/B4GALT2/ACSL5/MGST3/GSTM4/GSTZ1/ESD/ST3GAL2/CHST15/ACAT1/MPST/DLD/SCD5/GSTM5/PDK1/GSTM3/GGCT/PDHB/VCAN/MPC1/CHST12/KERA/PAPSS1/B4GALT3	35
BP	GO:0071560	cellular response to transforming growth factor beta stimulus	44/2619	249/18670	0.06095	0.197	0.1478	SFRP1/FOLR1/SOX9/SMAD3/GOT1/CFLAR/MTMR4/ADAM17/LTBP3/TRIM33/CX3CR1/HTRA1/MAPK7/ING2/GDF5/PENK/ADAMTSL2/RNF111/ZNF451/HPGD/FERMT2/POSTN/CDH5/APAF1/CDKN1C/CILP/PML/XCL1/PIN1/FUT8/UBB/FERMT1/NLK/ZFP36L2/PTPRK/LTBP4/USP9X/GDF9/ITGB5/CREB1/EP300/COL3A1/COL4A2/HSPA5	44
BP	GO:0034644	cellular response to UV	17/2619	82/18670	0.061	0.197	0.1478	PTN/MFAP4/ERCC1/ATR/CHEK1/USP47/MYC/AURKB/CASP9/DDB2/RUVBL2/PTPRK/CDKN1A/N4BP1/EP300/ATF4/RBL2	17
BP	GO:0001838	embryonic epithelial tube formation	24/2619	124/18670	0.06108	0.197	0.1478	SIX1/SFRP1/FOLR1/TCTN1/SOX9/IFT52/RALA/BMP4/SEMA4C/FZD3/BBS4/ARID1A/APAF1/DEAF1/ARHGAP35/GLMN/TMED2/PHACTR4/HIF1A/SETD2/BCL10/FZD6/TWIST1/FZD2	24
BP	GO:0019218	regulation of steroid metabolic process	24/2619	124/18670	0.06108	0.197	0.1478	PMVK/RORA/EPHX2/ERLIN2/APOE/KIT/ASAH1/SC5D/NFKB1/IFNG/APOC1/MBTPS1/AGT/TSPO/EGR1/AKR1C3/DHCR7/KPNB1/SOD1/PRKAA1/GAL/NFYC/LMF1/MVK	24
BP	GO:0019751	polyol metabolic process	24/2619	124/18670	0.06108	0.197	0.1478	GCH1/AKR1B1/DYSF/SPHK1/QDPR/PLCG2/SNCA/GOT1/PCBD1/PTH1R/SYNJ1/SORD/GK/ASAH1/SLC5A3/GPER1/NUDT11/PCK2/PLCE1/PLCD1/ISYNA1/INPP5E/COQ2/PTK2B	24
BP	GO:0048284	organelle fusion	24/2619	124/18670	0.06108	0.197	0.1478	TAP1/DYSF/SPHK1/FIS1/BNIP1/SNCA/PID1/SPG11/UVRAG/SEC22B/STX10/VTI1B/TAPBP/VAMP3/VPS16/SAMD9/LRMP/VAMP7/VPS8/TAP2/RAB20/CDK1/SYT1/STOML2	24
BP	GO:1903531	negative regulation of secretion by cell	38/2619	211/18670	0.06113	0.197	0.1478	TNFAIP3/GBP1/SFRP1/NOTCH1/CD200/TNFRSF1B/BTN2A2/IL27RA/TACR2/ANGPT1/SNCA/HLA-F/SYT11/TNFRSF21/CARD8/APOE/PTPN22/HRH3/RAB11FIP1/PTGER4/F2R/HADH/FOXF1/VAMP3/CRHBP/MAP4K4/GHSR/PML/PPP3CA/NMB/RHBDF2/CRY1/INHBB/RAP1B/IL13RA2/TLR8/CCR2/SRGN	38
BP	GO:0006284	base-excision repair	10/2619	42/18670	0.06131	0.197	0.1478	DNA2/TDG/RPA1/RPA3/USP47/MPG/POLG/WRN/HMGA1/HMGA2	10
BP	GO:0010559	regulation of glycoprotein biosynthetic process	10/2619	42/18670	0.06131	0.197	0.1478	IL15/NECAB3/IGF1/TMEM59/HBEGF/ITM2C/CCR7/TCF7L2/ACOT8/ARFGEF1	10
BP	GO:0010677	negative regulation of cellular carbohydrate metabolic process	10/2619	42/18670	0.06131	0.197	0.1478	SIK1/NUPR1/ENPP1/CBFA2T3/DDIT4/GSK3B/FAM3A/EP300/CRY1/PASK	10
BP	GO:0042149	cellular response to glucose starvation	10/2619	42/18670	0.06131	0.197	0.1478	SIK1/TBL2/HNRNPA1/PRKAA1/IFI16/XBP1/SESN1/ATF4/HSPA5/ASNS	10
BP	GO:0097028	dendritic cell differentiation	10/2619	42/18670	0.06131	0.197	0.1478	TREM2/HLA-G/LILRB2/RELB/RBPJ/AXL/HMGB1/CCR7/BATF/CEBPB	10
BP	GO:0099622	cardiac muscle cell membrane repolarization	10/2619	42/18670	0.06131	0.197	0.1478	SCN1B/ATP1B1/SNTA1/KCNQ1/KCNJ2/KCNJ8/KCNN2/AKAP9/CACNA1D/FLNA	10
BP	GO:0009791	post-embryonic development	18/2619	88/18670	0.06154	0.197	0.1478	EFEMP1/SLC18A2/ERCC1/ATM/NDN/IREB2/BCL11B/BMP4/PLEKHA1/RC3H2/ATRX/PRDM1/VEGFA/DHCR7/ERCC2/SCN9A/SGPL1/DSCAM	18
BP	GO:0097194	execution phase of apoptosis	18/2619	88/18670	0.06154	0.197	0.1478	DNASE1L3/BNIP1/MADD/FZD3/GPER1/APAF1/TP53BP2/TAOK1/IL6/DNASE2/HMGB1/TOP2A/KPNB1/CIDEB/DFFB/KPNA1/PAK2/RNF34	18
BP	GO:0048593	camera-type eye morphogenesis	22/2619	112/18670	0.06175	0.197	0.1478	PTN/DIO3/SOX9/RBP4/BMP4/FAT1/ROM1/ARID1A/LRP5/VEGFA/ALDH1A3/TSKU/TENM3/RS1/IRX5/PHACTR4/HIF1A/SIX3/RING1/DSCAM/TH/TWIST1	22
BP	GO:0098693	regulation of synaptic vesicle cycle	22/2619	112/18670	0.06175	0.197	0.1478	CDH2/SNCA/RIMS3/PREPL/SH3GL1/PRKCB/SYT11/FGF14/PFN2/GSK3B/PCDH17/MAGI2/ROCK1/PLD1/ADCY1/CACNB2/CACNA1D/SYT1/CYFIP1/SYN1/RAP1B/NAPA	22
BP	GO:0006906	vesicle fusion	19/2619	94/18670	0.06185	0.197	0.1478	TAP1/DYSF/SPHK1/SNCA/SPG11/UVRAG/SEC22B/STX10/VTI1B/TAPBP/VAMP3/VPS16/SAMD9/LRMP/VAMP7/VPS8/TAP2/RAB20/SYT1	19
BP	GO:0042158	lipoprotein biosynthetic process	19/2619	94/18670	0.06185	0.197	0.1478	PIGT/GPAA1/ZDHHC18/PIGK/PGAP2/ZDHHC4/ZDHHC17/APOE/PIGA/PIGP/DPM3/UGCG/ZDHHC3/PIGH/PPM1B/PIGZ/PIGC/ATG12/PGAP3	19
BP	GO:0006779	porphyrin-containing compound biosynthetic process	7/2619	26/18670	0.06193	0.197	0.1478	FECH/IREB2/UROD/UROS/TSPO/NFE2L1/CPOX	7
BP	GO:0007020	microtubule nucleation	7/2619	26/18670	0.06193	0.197	0.1478	TUBG2/NDE1/CLASP1/TUBGCP5/AKAP9/RANGRF/TUBGCP2	7
BP	GO:0021591	ventricular system development	7/2619	26/18670	0.06193	0.197	0.1478	SLC7A11/NME5/BBS4/TSKU/MNAT1/MYH10/CENPF	7
BP	GO:0034204	lipid translocation	7/2619	26/18670	0.06193	0.197	0.1478	ATP8B1/TMEM30A/ABCC1/ATP8A1/ATP11B/ABCB1/ATP10A	7
BP	GO:0060544	regulation of necroptotic process	7/2619	26/18670	0.06193	0.197	0.1478	BIRC3/SLC25A4/CFLAR/BIRC2/ARHGEF2/PELI1/CYLD	7
BP	GO:0060914	heart formation	7/2619	26/18670	0.06193	0.197	0.1478	SIX1/FOLR1/SMARCD3/PIM1/BMP4/TBX5/RBPJ	7
BP	GO:0070911	global genome nucleotide-excision repair	7/2619	26/18670	0.06193	0.197	0.1478	CETN2/ERCC1/RNF111/UBB/DDB2/ERCC2/GTF2H3	7
BP	GO:0071624	positive regulation of granulocyte chemotaxis	7/2619	26/18670	0.06193	0.197	0.1478	DYSF/THBS4/RAC2/XCL1/CCR7/CXCR2/CXCL8	7
BP	GO:0090174	organelle membrane fusion	20/2619	100/18670	0.06197	0.197	0.1478	TAP1/DYSF/SPHK1/BNIP1/SNCA/SPG11/UVRAG/SEC22B/STX10/VTI1B/TAPBP/VAMP3/VPS16/SAMD9/LRMP/VAMP7/VPS8/TAP2/RAB20/SYT1	20
BP	GO:2001023	regulation of response to drug	20/2619	100/18670	0.06197	0.197	0.1478	TACR2/SNCA/SYT11/HGF/PINK1/FGF20/GABRA4/SYT17/RGS4/CHRNA3/AGT/TRAP1/ARL6IP5/GDF9/ADIRF/GAL/SYT1/PYCR1/PSAP/HMGA2	20
BP	GO:0001977	renal system process involved in regulation of blood volume	5/2619	16/18670	0.06218	0.197	0.1478	HSD11B2/CORO2B/F2R/PDGFB/EMP2	5
BP	GO:0006004	fucose metabolic process	5/2619	16/18670	0.06218	0.197	0.1478	FUCA1/FUT1/POFUT1/FUT8/FUT4	5
BP	GO:0007567	parturition	5/2619	16/18670	0.06218	0.197	0.1478	HPGD/PTGFR/PLA2G4C/MAFF/LDOC1	5
BP	GO:0009208	pyrimidine ribonucleoside triphosphate metabolic process	5/2619	16/18670	0.06218	0.197	0.1478	NME4/NME7/NME5/NME3/CTPS1	5
BP	GO:0019372	lipoxygenase pathway	5/2619	16/18670	0.06218	0.197	0.1478	LTC4S/ALOX5AP/HPGD/GPX1/GPX4	5
BP	GO:0030033	microvillus assembly	5/2619	16/18670	0.06218	0.197	0.1478	TNIK/ATP8B1/PLD1/RAPGEF6/PODXL	5
BP	GO:0030397	membrane disassembly	5/2619	16/18670	0.06218	0.197	0.1478	PRKCB/CCNB2/CCNB1/CDK1/LPIN1	5
BP	GO:0032354	response to follicle-stimulating hormone	5/2619	16/18670	0.06218	0.197	0.1478	NOTCH1/EFNA5/PAPPA/GHSR/ASNS	5
BP	GO:0033033	negative regulation of myeloid cell apoptotic process	5/2619	16/18670	0.06218	0.197	0.1478	CCL5/CCR5/GHSR/NOD2/CXCR2	5
BP	GO:0042222	interleukin-1 biosynthetic process	5/2619	16/18670	0.06218	0.197	0.1478	JAK2/CMA1/IFNG/EGR1/TYROBP	5
BP	GO:0044794	positive regulation by host of viral process	5/2619	16/18670	0.06218	0.197	0.1478	APOE/PC/YTHDC2/PPIB/VAPA	5
BP	GO:0045618	positive regulation of keratinocyte differentiation	5/2619	16/18670	0.06218	0.197	0.1478	NOTCH1/FOXC1/NCOA3/PRKCH/MED1	5
BP	GO:0051081	nuclear envelope disassembly	5/2619	16/18670	0.06218	0.197	0.1478	PRKCB/CCNB2/CCNB1/CDK1/LPIN1	5
BP	GO:0072189	ureter development	5/2619	16/18670	0.06218	0.197	0.1478	SIX1/SOX9/BMP4/FOXF1/EMX2	5
BP	GO:0099170	postsynaptic modulation of chemical synaptic transmission	5/2619	16/18670	0.06218	0.197	0.1478	GHSR/USP8/PPP3CA/NRGN/CYFIP1	5
BP	GO:0001658	branching involved in ureteric bud morphogenesis	13/2619	59/18670	0.06251	0.1977	0.1483	SIX1/HOXA11/SOX9/PGF/CTNNBIP1/BMP4/LAMA5/AGT/SIX2/MYC/VEGFA/MAGED1/SMO	13
BP	GO:0001836	release of cytochrome c from mitochondria	13/2619	59/18670	0.06251	0.1977	0.1483	FAM162A/FIS1/CLU/HGF/BAD/PINK1/NOL3/GPX1/GPER1/IGF1/CIDEB/GGCT/PSMD10	13
BP	GO:0001885	endothelial cell development	13/2619	59/18670	0.06251	0.1977	0.1483	NOTCH4/STC1/RAP2C/PECAM1/TNMD/ROCK1/GPX1/PPP1R16B/CDH5/GSTM3/VEGFA/TJP2/RAP1B	13
BP	GO:0043388	positive regulation of DNA binding	13/2619	59/18670	0.06251	0.1977	0.1483	JAK2/NIPBL/FOXC1/EGF/PPARG/IFNG/IGF1/HMGB1/ERCC2/CEBPG/EP300/HMGA2/TWIST1	13
BP	GO:0048562	embryonic organ morphogenesis	50/2619	288/18670	0.06286	0.1981	0.1485	ZIC1/SIX1/HOXA11/EFEMP1/NOTCH1/FOLR1/SOX9/MAPK3/NIPBL/SMAD3/TCF7/RBP4/IFT52/MDFI/BMP4/C2CD3/WNT11/HOXB6/FZD3/BBS4/NAGLU/PRKRA/OSR2/MICAL2/ARID1A/HOXA4/FOXF1/SIX2/HOXB5/IFT140/ALDH1A3/IRX5/TMED2/HOXD9/SOD1/PHACTR4/HIF1A/HOXA5/SETD2/SIX3/ID2/CEP290/HOXC11/FZD6/HOXA7/SMO/TH/TWIST1/FZD2/SATB2	50
BP	GO:0050773	regulation of dendrite development	28/2619	149/18670	0.06313	0.1981	0.1485	PTN/SEMA4D/TNIK/SS18L1/EZH2/BAIAP2/ASAP1/APOE/GSK3B/PARP6/SIPA1L1/YWHAH/PLK2/CHRNA3/VAMP7/TLX2/CDC20/EPHA4/PPP3CA/CAMK1/CDKL5/CYFIP1/CAPRIN2/C21orf91/CAMK2B/ACTR2/BCL11A/NEDD4L	28
BP	GO:0001956	positive regulation of neurotransmitter secretion	6/2619	21/18670	0.06323	0.1981	0.1485	TACR2/SNCA/GPER1/CACNB2/CACNA1D/SYT1	6
BP	GO:0006293	nucleotide-excision repair, preincision complex stabilization	6/2619	21/18670	0.06323	0.1981	0.1485	ERCC1/RPA1/RPA3/DDB2/ERCC2/GTF2H3	6
BP	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion	6/2619	21/18670	0.06323	0.1981	0.1485	ERCC1/RPA1/RPA3/DDB2/ERCC2/GTF2H3	6
BP	GO:0007035	vacuolar acidification	6/2619	21/18670	0.06323	0.1981	0.1485	ATP6V0D1/DMXL2/TCIRG1/CLN6/SLC11A1/ATP6V0E2	6
BP	GO:0009713	catechol-containing compound biosynthetic process	6/2619	21/18670	0.06323	0.1981	0.1485	GCH1/SNCA/MOXD1/HDC/INSM1/TH	6
BP	GO:0030502	negative regulation of bone mineralization	6/2619	21/18670	0.06323	0.1981	0.1485	SOX9/ENPP1/LTBP3/HIF1A/PTK2B/SRGN	6
BP	GO:0032332	positive regulation of chondrocyte differentiation	6/2619	21/18670	0.06323	0.1981	0.1485	HOXA11/SOX9/SMAD3/GDF5/FGF18/ZNF219	6
BP	GO:0035162	embryonic hemopoiesis	6/2619	21/18670	0.06323	0.1981	0.1485	KIT/MED1/KDR/VEGFA/HIF1A/SH2B3	6
BP	GO:0035357	peroxisome proliferator activated receptor signaling pathway	6/2619	21/18670	0.06323	0.1981	0.1485	RXRA/MED1/PPARG/LMO3/ASXL2/TWIST1	6
BP	GO:0036344	platelet morphogenesis	6/2619	21/18670	0.06323	0.1981	0.1485	NBEAL2/CASP9/CIB1/EP300/ACTN1/C1GALT1C1	6
BP	GO:0042423	catecholamine biosynthetic process	6/2619	21/18670	0.06323	0.1981	0.1485	GCH1/SNCA/MOXD1/HDC/INSM1/TH	6
BP	GO:0048245	eosinophil chemotaxis	6/2619	21/18670	0.06323	0.1981	0.1485	CCL5/CCL8/SCG2/CCL13/LGALS3/CCL7	6
BP	GO:0055093	response to hyperoxia	6/2619	21/18670	0.06323	0.1981	0.1485	FAS/CDK4/PPARG/CAT/POLG/CDKN1A	6
BP	GO:0061213	positive regulation of mesonephros development	6/2619	21/18670	0.06323	0.1981	0.1485	SIX1/SOX9/AGT/VEGFA/MAGED1/SMO	6
BP	GO:1903055	positive regulation of extracellular matrix organization	6/2619	21/18670	0.06323	0.1981	0.1485	SOX9/SMAD3/CFLAR/AGT/IL6/CLASP1	6
BP	GO:2000114	regulation of establishment of cell polarity	6/2619	21/18670	0.06323	0.1981	0.1485	ROCK1/KRIT1/CDH5/PTK2B/RAP1B/ARFGEF1	6
BP	GO:2000738	positive regulation of stem cell differentiation	6/2619	21/18670	0.06323	0.1981	0.1485	PTN/SOX9/FOXC1/LTBP3/BMP4/TBX5	6
BP	GO:0009416	response to light stimulus	54/2619	314/18670	0.06355	0.199	0.1492	SIK1/PTN/SCARA3/GPR88/FECH/MFAP4/ERCC1/CIRBP/ATR/SLC7A11/METAP1/SDF4/CHEK1/B4GALT2/EGFR/DYNLRB1/KIT/USP47/GPX1/GUCA1A/CAT/ARRB1/ELANE/POLG/MYC/BRCA2/PML/DEAF1/AURKB/CASP9/DTL/RS1/DDB2/RUVBL2/PTPRK/WRN/AGRP/HIF1A/ERCC2/PRKAA1/CREB1/ID2/METAP2/CDKN1A/PDC/N4BP1/EP300/TRIM32/CRY1/KRAS/ATF4/ASNS/TH/RBL2	54
BP	GO:0060675	ureteric bud morphogenesis	14/2619	65/18670	0.06428	0.2012	0.1509	SIX1/HOXA11/SOX9/PGF/CTNNBIP1/BMP4/WNT11/LAMA5/AGT/SIX2/MYC/VEGFA/MAGED1/SMO	14
BP	GO:0002279	mast cell activation involved in immune response	11/2619	48/18670	0.06505	0.2028	0.1521	RASGRP1/IL4R/S100A13/KIT/FGR/FOXF1/RAC2/VAMP7/LAT/PIK3CD/IL13RA2	11
BP	GO:0009069	serine family amino acid metabolic process	11/2619	48/18670	0.06505	0.2028	0.1521	CBS/SDS/THNSL2/SLC7A11/GCAT/SERINC5/MPST/PSPH/AHCY/SRR/SEPHS1	11
BP	GO:0035272	exocrine system development	11/2619	48/18670	0.06505	0.2028	0.1521	SOX9/FOXC1/HGF/SEMA3A/EGFR/INSR/LAMA5/WLS/PLXND1/PLXNA1/XBP1	11
BP	GO:0051653	spindle localization	11/2619	48/18670	0.06505	0.2028	0.1521	NDE1/ASPM/ACTR3/NUSAP1/ARHGEF2/NDC80/CLASP1/DYNC1H1/LLGL2/KPNB1/ACTR2	11
BP	GO:0051972	regulation of telomerase activity	11/2619	48/18670	0.06505	0.2028	0.1521	PARP3/MAPK3/HNRNPA2B1/PPARG/MYC/HMBOX1/AURKB/PARP4/PRKCQ/PARM1/HNRNPD	11
BP	GO:0060324	face development	11/2619	48/18670	0.06505	0.2028	0.1521	CRISPLD2/MAPK3/NIPBL/LEF1/ASPH/PLEKHA1/BBS4/ALDH1A3/RAF1/EP300/SGPL1	11
BP	GO:0090199	regulation of release of cytochrome c from mitochondria	11/2619	48/18670	0.06505	0.2028	0.1521	FAM162A/CLU/HGF/BAD/PINK1/NOL3/GPX1/GPER1/IGF1/CIDEB/PSMD10	11
BP	GO:0046887	positive regulation of hormone secretion	25/2619	131/18670	0.06532	0.2035	0.1526	JAK2/RPH3AL/TACR2/SRI/MPC2/CD38/RBP4/BAD/EGFR/HFE/GPER1/ARRB1/OXCT1/SIRT3/VAMP7/ANO1/HIF1A/TMF1/NMB/TARDBP/TAC1/CREB1/GAL/TCF7L2/INHBB	25
BP	GO:0051208	sequestering of calcium ion	25/2619	131/18670	0.06532	0.2035	0.1526	CXCL9/CXCL10/PLCG2/SNCA/SRI/CXCL11/PTPRC/CCR5/NOL3/HTR2B/GPER1/F2R/LCK/ITPR2/MCOLN3/XCL1/CD19/PLCE1/CCR7/LIME1/TPCN1/MCOLN1/PTK2B/LETM1/DDIT3	25
BP	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	15/2619	71/18670	0.06559	0.204	0.153	JAK2/CCL5/CRLF1/IL15/PECAM1/KIT/CTF1/CD40/IFNG/IGF1/IL6/ARL2BP/IL6R/GHR/ERBB4	15
BP	GO:0031111	negative regulation of microtubule polymerization or depolymerization	9/2619	37/18670	0.06563	0.204	0.153	STMN2/SNCA/FGF13/ARHGEF2/CDH5/TAOK1/CLASP1/KATNB1/CIB1	9
BP	GO:0042307	positive regulation of protein import into nucleus	9/2619	37/18670	0.06563	0.204	0.153	ZIC1/ECT2/SMAD3/TPR/IFNG/TARDBP/FLNA/UBR5/SMO	9
BP	GO:0086010	membrane depolarization during action potential	9/2619	37/18670	0.06563	0.204	0.153	SCN1B/KCNJ2/ANK3/YWHAH/CACNB2/RANGRF/SCN9A/CACNA1D/SCN3A	9
BP	GO:1904358	positive regulation of telomere maintenance via telomere lengthening	9/2619	37/18670	0.06563	0.204	0.153	MAPK3/HNRNPA2B1/ATR/TNKS2/ATM/HMBOX1/AURKB/HNRNPA1/PRKCQ	9
BP	GO:0033673	negative regulation of kinase activity	45/2619	257/18670	0.06636	0.206	0.1545	TNFAIP3/DUSP5/SFRP1/CEBPA/IRAK3/ADAR/PRKAR2A/DUSP6/UCHL1/PTPRC/CDKN2C/DEPTOR/APOE/CHORDC1/SOCS1/LAX1/BMP4/DNAJA1/PTPN22/PTPN2/CHMP6/FGFR1OP/HSPB1/CBLB/IFNG/RGS4/TRIB1/PPM1E/LRP5/RASIP1/CDKN1C/TAF7/DUSP2/DNAJC3/NF2/TAOK3/CIB1/RHOH/PAK2/GGNBP2/KAT2B/CDKN1A/SH2B3/MVP/NUP62	45
BP	GO:0090305	nucleic acid phosphodiester bond hydrolysis	52/2619	302/18670	0.06636	0.206	0.1545	RNASE1/ERI3/DNASE1L3/DCLRE1C/ENPP1/ERCC1/POLD2/POLR2I/EXOSC7/DNASE1L1/DNA2/NHP2/RPA1/RNASE4/RNASE2/SAMHD1/RPA3/POLD4/CPSF7/ISG20/SETMAR/TATDN2/POP7/APAF1/DCP2/POLG/ANG/IL6/DNASE2/UBB/HMGB1/RAD50/DDB2/RAD1/TDP1/KPNB1/WRN/DDX1/AGO3/ERCC2/TSN/DFFB/C11orf80/KPNA1/RAD9A/NCBP2/EDC4/PIWIL2/RPP14/GTF2H3/RFC2/CSTF2	52
BP	GO:0061982	meiosis I cell cycle process	23/2619	119/18670	0.06648	0.2063	0.1547	CDC25B/ERCC1/KLHDC3/MYBL1/UBR2/ATM/PTTG1/ING2/RMI1/CKS2/BRCA2/UBB/RAD51C/RAD50/TOP2A/NDC1/C11orf80/CENPC/HSPA2/PIWIL2/RAD51B/PTTG2/FBXO5	23
BP	GO:1901224	positive regulation of NIK/NF-kappaB signaling	16/2619	77/18670	0.06651	0.2063	0.1547	SPHK1/TREM2/TRIP6/MALT1/EGFR/COPS8/RC3H2/CD27/CARD14/NR3C2/HMGB1/NOD2/AGO3/NOD1/TNFSF14/EP300	16
BP	GO:0070588	calcium ion transmembrane transport	54/2619	315/18670	0.0666	0.2065	0.1549	CXCL9/DYSF/CXCL10/ATP1B1/ATP2A3/PLCG2/SNCA/SRI/CXCL11/PTPRC/FGF14/ATP2C1/PRNP/BIN1/CCR5/NOL3/HTR2B/EHD3/PHB/GPER1/TSPAN13/GPM6A/F2R/TMCO1/LCK/ITPR2/MCOLN3/ATP2B2/S100A1/FAM155A/XCL1/CD19/P2RX4/CALCR/PLCE1/PKD2L1/CCR7/MICU1/CACNB2/ORAI3/REM1/LIME1/TPCN1/MCOLN1/ATP2B4/CACNA1D/TRPV2/HSPA2/CACNA2D3/YME1L1/PTK2B/STOML2/LETM1/DDIT3	54
BP	GO:0051053	negative regulation of DNA metabolic process	29/2619	156/18670	0.06669	0.2066	0.155	PARP3/SMCHD1/FBXW7/ERCC1/NBN/ATR/CHEK2/TNKS2/TRIP12/ATM/THOC1/PPARG/DONSON/GZMA/GPER1/DCP2/HCRT/BRCA2/ZNF93/HNRNPA1/UBQLN4/RAD50/SMC1A/TIMELESS/UBR5/ZNF91/HMGA2/TWIST1/FBXO5	29
BP	GO:0016485	protein processing	56/2619	328/18670	0.06675	0.2067	0.1551	C7/LGMN/BIRC3/GAS1/CPA3/RIPK2/PROS1/CLU/PCSK1/SUSD4/BAD/PRNP/IFT52/SERPINE1/CARD8/BIRC2/BIRC7/IGLV1-44/C2CD3/PCSK7/NOL3/SPON1/CMA1/CPD/ASPH/CYFIP2/CFI/PHB/SPCS3/SEC11A/CD81/CR1/COMP/TMEM59/PSENEN/CD19/CPE/C4BPB/DHCR24/ADAMTS3/CST7/IGLC1/CIDEB/OGT/IFI16/APH1B/CTSG/METAP2/MIPEP/YME1L1/STOML2/APH1A/CFP/CORIN/SRGN/CD59	56
BP	GO:0019932	second-messenger-mediated signaling	73/2619	439/18670	0.06684	0.2068	0.1551	CXCL9/GBP1/PDK2/CXCL10/SPHK1/ATP1B1/TREM2/NDNF/SOX9/FIS1/PLCG2/PRKAR2A/SRI/DDAH1/CXCL11/TMEM100/CAMTA1/NDUFS4/PTPRC/PTH1R/EGFR/PRNP/MCTP1/CX3CR1/ADA/APOE/GSK3B/MAPK7/CCR5/DYRK2/HTR2B/SELE/PTGER4/GPER1/CXCR4/PTGFR/ZAP70/ADRB2/CD3E/DDAH2/ITPR2/NPR2/TRAT1/AGT/IGF1/NOS3/KDR/ADCY1/VEGFA/P2RX4/CALCR/PLCE1/CCR7/LGR5/HOMER3/CXCR2/PPP3CA/LAT/MCOLN1/PRKAA1/ATP2B4/CIB1/ADCY2/AKAP13/GAL/FHL2/CRTC3/CXCL8/PTK2B/CCR2/NR5A2/CALML4/CXCR6	73
BP	GO:0002223	stimulatory C-type lectin receptor signaling pathway	22/2619	113/18670	0.06693	0.2068	0.1551	PLCG2/SKP1/MALT1/PSMB9/PSMC2/NFKB1/RELB/PSMB6/CHUK/PSMC3/PSMD8/PSMB5/PSMD10/MUC5AC/IKBKG/RAF1/PAK2/BCL10/EP300/KRAS/ICAM3/NRAS	22
BP	GO:0032609	interferon-gamma production	22/2619	113/18670	0.06693	0.2068	0.1551	RASGRP1/IL27RA/RIPK2/ITK/PRNP/CD96/PTPN22/TCIRG1/CD3E/TXK/AXL/XCL1/SLC11A1/TNFSF4/HMGB1/CCR7/BTN3A1/CD2/IL6R/CEBPG/TLR8/CCR2	22
BP	GO:0048640	negative regulation of developmental growth	22/2619	113/18670	0.06693	0.2068	0.1551	SFRP1/JARID2/LGMN/WWC3/SEMA4D/SEMA4A/SEMA3A/FGF13/RBP4/BMP4/SEMA4C/ADRB2/RGS4/MAPK11/SEMA3F/CTDP1/TBX5/SEMA3E/GAL/CDKN1A/BCL11A/STC2	22
BP	GO:0051048	negative regulation of secretion	42/2619	238/18670	0.06694	0.2068	0.1551	TNFAIP3/GBP1/SFRP1/NOTCH1/CD200/TNFRSF1B/BTN2A2/IL27RA/TACR2/ANGPT1/SNCA/HLA-F/SYT11/TNFRSF21/EGF/COMT/CARD8/ADA/APOE/PTPN22/HRH3/RAB11FIP1/PTGER4/F2R/HADH/FOXF1/VAMP3/CRHBP/MAP4K4/GHSR/PML/PLA2R1/PPP3CA/NMB/RHBDF2/CRY1/INHBB/RAP1B/IL13RA2/TLR8/CCR2/SRGN	42
BP	GO:0043502	regulation of muscle adaptation	21/2619	107/18670	0.06728	0.2077	0.1558	SGCA/NOTCH1/JARID2/TNFRSF1B/IGFBP5/SMAD3/MTMR4/GTF2IRD1/NOL3/ROCK1/RGS4/AGT/CTDP1/IGF1/NOS3/PIN1/P2RX4/PPP3CA/ATP2B4/CDK9/CAMK2B	21
BP	GO:0006497	protein lipidation	18/2619	89/18670	0.06744	0.208	0.156	PIGT/GPAA1/ZDHHC18/PIGK/PGAP2/ZDHHC4/ZDHHC17/PIGA/PIGP/DPM3/UGCG/ZDHHC3/PIGH/PPM1B/PIGZ/PIGC/ATG12/PGAP3	18
BP	GO:0055013	cardiac muscle cell development	18/2619	89/18670	0.06744	0.208	0.156	SGCB/MYOM2/BMP4/NEBL/MAML1/RGS4/AGT/CTDP1/IGF1/CCNB1/FHOD3/SORBS2/VEGFA/PIN1/AKAP13/CDK1/CXADR/MYH10	18
BP	GO:0007018	microtubule-based movement	49/2619	283/18670	0.06745	0.208	0.156	MREG/IFT46/RASGRP1/DNAL4/ARL3/NDE1/UCHL1/RPGR/SYNE2/SPG11/NME5/DLGAP5/KIF2A/RACGAP1/IFT52/ACTR3/DYNLRB1/BLOC1S1/TRAK1/BBS4/TTLL1/KIF18B/HSPB1/KIF5C/CENPE/KIF11/PCM1/DYNC1I1/VAMP7/KIF4A/KIF15/TNPO1/CLUAP1/DYNC1H1/IFT140/UBB/SFPQ/KPNB1/PEX14/SOD1/SPAST/KATNB1/HIF1A/IFT22/KIF20A/OFD1/ACTR2/TRIM58/DYNC2LI1	49
BP	GO:1903426	regulation of reactive oxygen species biosynthetic process	20/2619	101/18670	0.0675	0.208	0.156	JAK2/SLC18A2/SNCA/CLU/SMAD3/DDAH1/RAB27A/CFLAR/CX3CR1/INSR/DDAH2/IFNG/AGT/ASS1/TSPO/TRAP1/P2RX4/HBB/ATP2B4/PTK2B	20
BP	GO:0044070	regulation of anion transport	19/2619	95/18670	0.06756	0.208	0.156	SNCA/PRNP/STC1/TNFRSF11A/APOE/HRH3/RGS4/AGT/ATP8A1/CA2/P2RX4/PLA2R1/ARL6IP5/NCOR1/ABCB1/RAB11B/FABP3/CEBPB/ATF4	19
BP	GO:0055006	cardiac cell development	19/2619	95/18670	0.06756	0.208	0.156	NOTCH1/SGCB/MYOM2/BMP4/NEBL/MAML1/RGS4/AGT/CTDP1/IGF1/CCNB1/FHOD3/SORBS2/VEGFA/PIN1/AKAP13/CDK1/CXADR/MYH10	19
BP	GO:0016331	morphogenesis of embryonic epithelium	28/2619	150/18670	0.06764	0.2082	0.1561	SIX1/SFRP1/FOLR1/TCTN1/AR/SOX9/IFT52/RALA/BMP4/SEMA4C/FZD3/BBS4/LAMA5/ARID1A/APAF1/DEAF1/ALDH1A3/ARHGAP35/GLMN/TMED2/JAG2/PHACTR4/HIF1A/SETD2/BCL10/FZD6/TWIST1/FZD2	28
BP	GO:0045747	positive regulation of Notch signaling pathway	12/2619	54/18670	0.06788	0.2087	0.1565	NOTCH1/NOTCH4/KIT/RFNG/MAML1/PRKCI/NOS3/RBPJ/NOD2/JAG2/KAT2B/EP300	12
BP	GO:0051353	positive regulation of oxidoreductase activity	12/2619	54/18670	0.06788	0.2087	0.1565	GCH1/SNCA/APOE/HTR2B/IFNG/AGT/S100A1/NOD2/HIF1A/NOD1/KRAS/PTK2B	12
BP	GO:0007389	pattern specification process	74/2619	446/18670	0.06797	0.2089	0.1567	ZIC1/SIX1/HOXA11/MTF2/SFRP1/NOTCH1/FOLR1/TCTN1/AR/GALNT11/HOXA10/HOXC10/SMAD3/FOXC1/MEOX1/SEMA3A/NLE1/ATM/SMARCD3/CTNNBIP1/AP1B1/IFT52/STC1/MDFI/BMP4/C2CD3/HOXB6/LEF1/RNF111/RFNG/MNS1/ASPH/BBS4/FKBP8/MICAL2/HOXA4/EVX1/FOXF1/POFUT1/WLS/SEMA3F/LRP5/SIX2/TBX5/EFNB1/NBL1/PSKH1/RBPJ/EN1/EED/HOXB5/IFT140/CXXC4/TMED2/HOXD9/ABI1/HIF1A/HOXA5/SIM2/BPTF/SIX3/HOXC11/RING1/ERBB4/EP300/ETS2/HOXA7/SMO/EMX2/OFD1/PBX3/DDIT3/SATB2/DYNC2LI1	74
BP	GO:0009101	glycoprotein biosynthetic process	59/2619	348/18670	0.06833	0.2098	0.1574	MGAT4C/GAL3ST4/GALNT11/UST/GALNT10/SDF2/IL15/EOGT/TNIP1/MPI/B4GALT2/UBE2J1/EXT2/NECAB3/TMEM258/B3GALNT1/FUT1/DPM3/TRAK1/RFNG/GCNT3/DPY19L2P2/DPAGT1/ST3GAL2/CHST15/POFUT1/EXTL2/IGF1/DAD1/MAN1C1/B4GALT7/TMEM59/MAN1B1/HBEGF/ITM2C/GALNT3/DHDDS/FUT8/CCR7/DDOST/ALG6/OGT/MUC5AC/PMM1/TCF7L2/ACOT8/VCAN/GOLPH3/ABO/ST8SIA2/ASGR1/FUT4/NPC1/C1GALT1C1/CHST12/ARFGEF1/LMF1/VEGFB/B4GALT3	59
BP	GO:1902115	regulation of organelle assembly	35/2619	194/18670	0.06849	0.2102	0.1577	NUPR1/LCP1/CEP135/MDM1/SDC1/SYNE2/PIKFYVE/ASAP1/PINK1/TPR/SEC22B/SPAG5/ARHGEF2/MNS1/BBS4/RABEP2/DRG1/PLK2/CHMP2A/DYNC1H1/IFT140/ARHGAP35/ALMS1/SMC1A/PRKAA1/CYLD/CHMP1B/AKAP13/VDAC3/CDKL5/KAT2B/SPICE1/STYXL1/NUP62/DYNC2LI1	35
BP	GO:0071322	cellular response to carbohydrate stimulus	27/2619	144/18670	0.06856	0.2104	0.1578	FIS1/COLEC12/SRI/PRKCB/MPC2/BAD/EFNA5/CMA1/GPER1/ARRB1/OXCT1/POLG/PTPRN2/LRP5/MAP4K4/PCK2/SLC2A5/ANO1/PPP3CA/HIF1A/PRKAA1/RAF1/RAB11B/XBP1/SERPINF1/TH/PIK3CA	27
BP	GO:0051495	positive regulation of cytoskeleton organization	40/2619	226/18670	0.0697	0.2129	0.1597	SFRP1/IQGAP2/ACTR3B/STMN2/ARPC1A/SMAD3/CDC42EP3/ARL2/FCHSD2/PFN2/BAIAP2/NCK2/ACTR3/LIMCH1/NTF3/BIN1/WNT11/SPAG5/DRG1/PPM1E/CLASP1/MAGEL2/MYOC/DYNC1H1/SCIN/CCR7/AP1AR/SPAST/KATNB1/ARPC5L/AKAP9/NF2/TAC1/CTTN/HIP1R/CYFIP1/FLNA/PTK2B/ACTR2/NUP62	40
BP	GO:0006486	protein glycosylation	45/2619	258/18670	0.06986	0.2129	0.1597	MGAT4C/GALNT11/GALNT10/SDF2/IL15/EOGT/MPI/B4GALT2/UBE2J1/EXT2/TMEM258/B3GALNT1/FUT1/DPM3/TRAK1/RFNG/GCNT3/DPY19L2P2/DPAGT1/ST3GAL2/POFUT1/EXTL2/DAD1/MAN1C1/B4GALT7/TMEM59/MAN1B1/GALNT3/DHDDS/FUT8/DDOST/ALG6/OGT/MUC5AC/PMM1/ABO/ST8SIA2/ASGR1/FUT4/NPC1/C1GALT1C1/ARFGEF1/LMF1/VEGFB/B4GALT3	45
BP	GO:0043413	macromolecule glycosylation	45/2619	258/18670	0.06986	0.2129	0.1597	MGAT4C/GALNT11/GALNT10/SDF2/IL15/EOGT/MPI/B4GALT2/UBE2J1/EXT2/TMEM258/B3GALNT1/FUT1/DPM3/TRAK1/RFNG/GCNT3/DPY19L2P2/DPAGT1/ST3GAL2/POFUT1/EXTL2/DAD1/MAN1C1/B4GALT7/TMEM59/MAN1B1/GALNT3/DHDDS/FUT8/DDOST/ALG6/OGT/MUC5AC/PMM1/ABO/ST8SIA2/ASGR1/FUT4/NPC1/C1GALT1C1/ARFGEF1/LMF1/VEGFB/B4GALT3	45
BP	GO:0001569	branching involved in blood vessel morphogenesis	8/2619	32/18670	0.06992	0.2129	0.1597	NOTCH4/LEF1/RBM15/VEGFA/PLXND1/SEMA3E/COL4A1/FKBPL	8
BP	GO:0003176	aortic valve development	8/2619	32/18670	0.06992	0.2129	0.1597	NOTCH1/TNFRSF1B/SOX9/BMP4/ROCK1/NOS3/RBPJ/TWIST1	8
BP	GO:0006356	regulation of transcription by RNA polymerase I	8/2619	32/18670	0.06992	0.2129	0.1597	POLR2L/DDX11/ERBB2/MED1/HEATR1/WDR43/FLNA/ATF4	8
BP	GO:0035510	DNA dealkylation	8/2619	32/18670	0.06992	0.2129	0.1597	FTO/TDG/APOBEC3C/MPG/ASCC3/APOBEC3B/USP9X/ASCC1	8
BP	GO:0042311	vasodilation	8/2619	32/18670	0.06992	0.2129	0.1597	GCH1/APOE/GPX1/ADRB2/AGT/NOS3/CPS1/SOD1	8
BP	GO:0042744	hydrogen peroxide catabolic process	8/2619	32/18670	0.06992	0.2129	0.1597	SNCA/GPX3/PRDX6/PXDN/GPX1/CAT/HBB/PRDX2	8
BP	GO:0045987	positive regulation of smooth muscle contraction	8/2619	32/18670	0.06992	0.2129	0.1597	SPHK1/TACR2/ADA/KIT/GPER1/F2R/GHSR/CTTN	8
BP	GO:0048841	regulation of axon extension involved in axon guidance	8/2619	32/18670	0.06992	0.2129	0.1597	SEMA4D/SEMA4A/SEMA3A/SEMA4C/SEMA3F/VEGFA/SEMA3E/DSCAM	8
BP	GO:0070570	regulation of neuron projection regeneration	8/2619	32/18670	0.06992	0.2129	0.1597	PTN/PTPRF/HGF/CERS2/KLK8/MAP4K4/EPHA4/LRIG2	8
BP	GO:0086019	cell-cell signaling involved in cardiac conduction	8/2619	32/18670	0.06992	0.2129	0.1597	SCN1B/KCNQ1/CACNB2/KCNN2/RANGRF/CACNA1D/CXADR/FLNA	8
BP	GO:1901976	regulation of cell cycle checkpoint	8/2619	32/18670	0.06992	0.2129	0.1597	RFWD3/CHEK2/THOC1/TPR/LCMT1/NDC80/CCNB1/CRY1	8
BP	GO:2000778	positive regulation of interleukin-6 secretion	8/2619	32/18670	0.06992	0.2129	0.1597	LILRA2/F2R/HMGB1/LPL/IL17RC/XBP1/TLR8/TWIST1	8
BP	GO:0034284	response to monosaccharide	37/2619	207/18670	0.06992	0.2129	0.1597	FIS1/SRI/APOM/MPC2/BAD/ANGPT2/EFNA5/CMA1/RMI1/GPER1/CAT/ARRB1/OXCT1/POLG/PTPRN2/LRP5/MAP4K4/EGR1/NAMPT/PCK2/TXN2/SLC2A5/ANO1/PPP3CA/VAMP2/LPL/HIF1A/PRKAA1/RAF1/RAB11B/TCF7L2/ENSA/XBP1/PTK2B/SERPINF1/TH/PIK3CA	37
BP	GO:0043966	histone H3 acetylation	13/2619	60/18670	0.06998	0.213	0.1597	CHEK1/NAP1L2/TADA3/LEF1/ZNF451/TAF10/BRPF1/BRCA2/TAF9B/KAT6A/YEATS2/KAT2B/PIWIL2	13
BP	GO:0000096	sulfur amino acid metabolic process	10/2619	43/18670	0.07026	0.2132	0.1599	CBS/BHMT2/SLC7A11/COMT/SMS/MSRA/MPST/CPS1/AHCY/TXN2	10
BP	GO:0006692	prostanoid metabolic process	10/2619	43/18670	0.07026	0.2132	0.1599	HPGDS/PTGS1/TBXAS1/CES2/HPGD/AKR1C3/PTGDS/ACOX1/CBR1/AKR1C4	10
BP	GO:0006693	prostaglandin metabolic process	10/2619	43/18670	0.07026	0.2132	0.1599	HPGDS/PTGS1/TBXAS1/CES2/HPGD/AKR1C3/PTGDS/ACOX1/CBR1/AKR1C4	10
BP	GO:0021762	substantia nigra development	10/2619	43/18670	0.07026	0.2132	0.1599	ZNF430/YWHAH/NDRG2/S100A1/SEC16A/RAD1/PADI2/NDUFS3/PLP1/HSPA5	10
BP	GO:1901985	positive regulation of protein acetylation	10/2619	43/18670	0.07026	0.2132	0.1599	MAPK3/NAP1L2/ARRB1/AUTS2/TAOK1/RUVBL2/KAT5/CAMK1/PRKAA1/PIWIL2	10
BP	GO:0055007	cardiac muscle cell differentiation	25/2619	132/18670	0.07028	0.2132	0.1599	SIK1/CBY1/SGCB/MYOM2/RXRA/BMP4/NEBL/ARID1A/MAML1/RGS4/AGT/CTDP1/IGF1/TBX5/CCNB1/FHOD3/RBPJ/SORBS2/VEGFA/PIN1/AKAP13/CDK1/CXADR/FZD7/MYH10	25
BP	GO:0008217	regulation of blood pressure	33/2619	182/18670	0.07101	0.2152	0.1614	GCH1/PTGS1/AR/CPA3/SMAD3/DDAH1/EPHX2/HSD11B2/CORO2B/CMA1/PPARG/BBS4/F2R/ADRB2/POSTN/NPR2/AGT/LRP5/NOS3/NPY1R/NAMPT/PDGFB/P2RX4/SLC2A5/SOD1/HBB/RNPEP/EMP2/TAC1/CTSG/ID2/ATP2B1/CORIN	33
BP	GO:0030041	actin filament polymerization	33/2619	182/18670	0.07101	0.2152	0.1614	IQGAP2/ACTR3B/JAK2/ARPC1A/MICALL2/TMOD1/CDC42EP3/FCHSD2/PFN2/BAIAP2/NCK2/ACTR3/PSTPIP2/CAPZA1/BIN1/BBS4/ANG/TMOD2/FHOD3/MAGEL2/MSRB2/SCIN/CCR7/AP1AR/TMSB10/TTC17/ARPC5L/CTTN/HIP1R/CYFIP1/PTK2B/ARFGEF1/ACTR2	33
BP	GO:0048706	embryonic skeletal system development	24/2619	126/18670	0.07106	0.2153	0.1615	SIX1/HOXA11/NIPBL/SMAD3/RBP4/MDFI/BMP4/WNT11/HOXB6/OSR2/HOXA4/SIX2/DEAF1/HOXB5/IFT140/IRX5/HOXD9/HOXA5/MBTD1/SETD2/HOXC11/HOXA7/TWIST1/SATB2	24
BP	GO:0002526	acute inflammatory response	39/2619	220/18670	0.07111	0.2153	0.1615	NUPR1/C7/DNASE1L3/PROS1/CLU/SERPINA3/SUSD4/SERPINA1/CTNNBIP1/TNFRSF11A/HLA-E/ITIH4/HFE/IGLV1-44/PPARG/CFI/PHB/F8/ELANE/CD81/CR1/ASS1/IL6/APOL2/CD19/TNFSF4/CCR7/C4BPB/CXCR2/IGLC1/MBL2/TAC1/IL6R/VNN1/CEBPB/IL22/REG3A/CFP/CD59	39
BP	GO:0072171	mesonephric tubule morphogenesis	14/2619	66/18670	0.07151	0.2164	0.1623	SIX1/HOXA11/SOX9/PGF/CTNNBIP1/BMP4/WNT11/LAMA5/AGT/SIX2/MYC/VEGFA/MAGED1/SMO	14
BP	GO:0007127	meiosis I	22/2619	114/18670	0.07241	0.219	0.1642	CDC25B/KLHDC3/MYBL1/UBR2/ATM/PTTG1/ING2/RMI1/CKS2/BRCA2/UBB/RAD51C/RAD50/TOP2A/NDC1/C11orf80/CENPC/HSPA2/PIWIL2/RAD51B/PTTG2/FBXO5	22
BP	GO:0034968	histone lysine methylation	22/2619	114/18670	0.07241	0.219	0.1642	MTF2/JARID2/SUZ12/WDR61/DNMT1/EZH2/ARID4B/RLF/SETD5/KDM3A/SETMAR/SMYD2/AUTS2/WDR5B/SETD1B/ATRX/EED/ARID4A/OGT/SETD2/SUV39H2/CXXC1	22
BP	GO:0019226	transmission of nerve impulse	15/2619	72/18670	0.07256	0.219	0.1643	SCN1B/GPR88/NTRK2/TYMP/ANK3/GPER1/S1PR1/AGT/HCRT/GHSR/P2RX4/SOD1/SCN9A/KCNMB2/SCN3A	15
BP	GO:0032024	positive regulation of insulin secretion	15/2619	72/18670	0.07256	0.219	0.1643	JAK2/RPH3AL/SRI/MPC2/CD38/RBP4/BAD/GPER1/ARRB1/OXCT1/SIRT3/ANO1/HIF1A/TARDBP/TCF7L2	15
BP	GO:0035019	somatic stem cell population maintenance	15/2619	72/18670	0.07256	0.219	0.1643	SFRP1/SOX9/POLR2J/POLR2I/POLR2L/POLR2E/POLR2F/KIT/POLR2C/SIX2/POLR2G/RBPJ/ZFP36L2/DPPA4/RAF1	15
BP	GO:0061180	mammary gland epithelium development	15/2619	72/18670	0.07256	0.219	0.1643	AR/JAK2/MED1/GPX1/FOXF1/LRP5/BRCA2/PML/DEAF1/HIF1A/HOXA5/ID2/ERBB4/CEBPB/SMO	15
BP	GO:0032526	response to retinoic acid	21/2619	108/18670	0.07294	0.2201	0.165	BRINP1/SETX/WNT5B/SOX9/IGFBP2/BRINP3/SLC10A3/MICB/NDUFA13/CD38/ATM/RBP4/RXRA/WNT11/PPARG/TIE1/BRINP2/CREB1/PTK2B/FZD7/SERPINF1	21
BP	GO:0055021	regulation of cardiac muscle tissue growth	16/2619	78/18670	0.07324	0.2207	0.1656	NOTCH1/JARID2/RBP4/PIM1/FGF20/RGS4/ZFPM2/MAPK11/CTDP1/IGF1/TBX5/CCNB1/RBPJ/PIN1/CDK1/ERBB4	16
BP	GO:0072028	nephron morphogenesis	16/2619	78/18670	0.07324	0.2207	0.1656	SIX1/HOXA11/STAT1/SOX9/PGF/CTNNBIP1/BMP4/WNT11/KLHL3/LAMA5/AGT/SIX2/MYC/VEGFA/MAGED1/SMO	16
BP	GO:0060420	regulation of heart growth	17/2619	84/18670	0.07361	0.2216	0.1662	NOTCH1/JARID2/DUSP6/RBP4/PIM1/FGF20/RGS4/ZFPM2/MAPK11/CTDP1/IGF1/TBX5/CCNB1/RBPJ/PIN1/CDK1/ERBB4	17
BP	GO:0002448	mast cell mediated immunity	11/2619	49/18670	0.0737	0.2216	0.1662	RASGRP1/IL4R/S100A13/KIT/FGR/FOXF1/RAC2/VAMP7/LAT/PIK3CD/IL13RA2	11
BP	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	11/2619	49/18670	0.0737	0.2216	0.1662	TNFAIP3/STAT1/RORA/TNIP1/TNIP3/CARD8/OPTN/PPM1B/HDAC1/RHOH/RIOK3	11
BP	GO:0061912	selective autophagy	11/2619	49/18670	0.0737	0.2216	0.1662	MAPK3/RIPK2/VPS13C/TBK1/PINK1/KLHL3/ADRB2/ATG13/OPTN/NOD1/CLEC16A	11
BP	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	11/2619	49/18670	0.0737	0.2216	0.1662	SFRP1/PTPRC/ATF3/PEA15/GPER1/AGT/PML/ITM2C/CYLD/PAK2/BCL10	11
BP	GO:0051304	chromosome separation	18/2619	90/18670	0.07372	0.2216	0.1662	ATM/DLGAP5/PTTG1/TPR/BUB1B/LCMT1/RMI1/NCAPH/NDC80/CENPE/CCNB1/CDC20/AURKB/TOP2A/TACC3/PTTG2/CENPF/FBXO5	18
BP	GO:0090169	regulation of spindle assembly	7/2619	27/18670	0.07389	0.2219	0.1665	TPR/SPAG5/DRG1/CHMP2A/DYNC1H1/SMC1A/CHMP1B	7
BP	GO:0051348	negative regulation of transferase activity	49/2619	285/18670	0.0743	0.2224	0.1668	TNFAIP3/DUSP5/SFRP1/CEBPA/IRAK3/PARP3/ADAR/PRKAR2A/DUSP6/UCHL1/PTPRC/CDKN2C/DEPTOR/APOE/GSK3B/CHORDC1/SOCS1/LAX1/BMP4/DNAJA1/PTPN22/PPARG/PTPN2/CHMP6/FGFR1OP/HSPB1/CBLB/IFNG/RGS4/TRIB1/PPM1E/LRP5/RASIP1/CDKN1C/TAF7/DUSP2/DNAJC3/NF2/TAOK3/CIB1/RHOH/PAK2/GGNBP2/KAT2B/CDKN1A/SH2B3/MVP/NUP62/FBXO5	49
BP	GO:0016571	histone methylation	26/2619	139/18670	0.07449	0.2224	0.1668	MTF2/JARID2/SUZ12/WDR61/DNMT1/EZH2/ARID4B/PRMT5/RLF/SETD5/KDM3A/SETMAR/SMYD2/AUTS2/WDR5B/SETD1B/ATRX/SATB1/EED/PAXBP1/ARID4A/OGT/SETD2/PRDM4/SUV39H2/CXXC1	26
BP	GO:0002371	dendritic cell cytokine production	4/2619	12/18670	0.07536	0.2224	0.1668	KIT/NOD2/DDX1/DDX21	4
BP	GO:0002468	dendritic cell antigen processing and presentation	4/2619	12/18670	0.07536	0.2224	0.1668	SLC11A1/CCR7/NOD2/NOD1	4
BP	GO:0002863	positive regulation of inflammatory response to antigenic stimulus	4/2619	12/18670	0.07536	0.2224	0.1668	HLA-E/CD28/CD81/CCR7	4
BP	GO:0003161	cardiac conduction system development	4/2619	12/18670	0.07536	0.2224	0.1668	NOTCH1/MAML1/TBX5/ID2	4
BP	GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis	4/2619	12/18670	0.07536	0.2224	0.1668	STAT1/BMP4/SIX2/SMO	4
BP	GO:0006662	glycerol ether metabolic process	4/2619	12/18670	0.07536	0.2224	0.1668	DHRS7B/PEX7/TXN2/AGPS	4
BP	GO:0006983	ER overload response	4/2619	12/18670	0.07536	0.2224	0.1668	GSK3B/TMCO1/HSPA5/DDIT3	4
BP	GO:0009265	2'-deoxyribonucleotide biosynthetic process	4/2619	12/18670	0.07536	0.2224	0.1668	ADK/GUK1/DCTD/TYMS	4
BP	GO:0014831	gastro-intestinal system smooth muscle contraction	4/2619	12/18670	0.07536	0.2224	0.1668	TACR2/KIT/HTR2B/GHSR	4
BP	GO:0014889	muscle atrophy	4/2619	12/18670	0.07536	0.2224	0.1668	IL15/CFLAR/NOL3/GATM	4
BP	GO:0031507	heterochromatin assembly	4/2619	12/18670	0.07536	0.2224	0.1668	SMCHD1/TPR/HMGA1/HMGA2	4
BP	GO:0042118	endothelial cell activation	4/2619	12/18670	0.07536	0.2224	0.1668	CXCL10/APOLD1/PRMT5/P2RX4	4
BP	GO:0043922	negative regulation by host of viral transcription	4/2619	12/18670	0.07536	0.2224	0.1668	CCL5/HDAC1/TARDBP/HMGA2	4
BP	GO:0046385	deoxyribose phosphate biosynthetic process	4/2619	12/18670	0.07536	0.2224	0.1668	ADK/GUK1/DCTD/TYMS	4
BP	GO:0048302	regulation of isotype switching to IgG isotypes	4/2619	12/18670	0.07536	0.2224	0.1668	IL27RA/PTPRC/CD28/CD40	4
BP	GO:0051132	NK T cell activation	4/2619	12/18670	0.07536	0.2224	0.1668	ELF4/IL15/HSPH1/IL6R	4
BP	GO:0051481	negative regulation of cytosolic calcium ion concentration	4/2619	12/18670	0.07536	0.2224	0.1668	SMAD3/GOT1/KCNK3/ATP2B1	4
BP	GO:0051549	positive regulation of keratinocyte migration	4/2619	12/18670	0.07536	0.2224	0.1668	MAP4K4/HBEGF/HAS2/MAPRE2	4
BP	GO:0051873	killing by host of symbiont cells	4/2619	12/18670	0.07536	0.2224	0.1668	ELANE/TUSC2/MBL2/CTSG	4
BP	GO:0051988	regulation of attachment of spindle microtubules to kinetochore	4/2619	12/18670	0.07536	0.2224	0.1668	ECT2/RACGAP1/SPAG5/CCNB1	4
BP	GO:0060742	epithelial cell differentiation involved in prostate gland development	4/2619	12/18670	0.07536	0.2224	0.1668	NOTCH1/AR/RXRA/PSAP	4
BP	GO:0060900	embryonic camera-type eye formation	4/2619	12/18670	0.07536	0.2224	0.1668	ARID1A/ALDH1A3/PHACTR4/TWIST1	4
BP	GO:0070493	thrombin-activated receptor signaling pathway	4/2619	12/18670	0.07536	0.2224	0.1668	IQGAP2/SNCA/HPGD/F2R	4
BP	GO:0071481	cellular response to X-ray	4/2619	12/18670	0.07536	0.2224	0.1668	SFRP1/NIPBL/ATM/HMGA2	4
BP	GO:0072520	seminiferous tubule development	4/2619	12/18670	0.07536	0.2224	0.1668	AR/ING2/ATRX/UBB	4
BP	GO:0098885	modification of postsynaptic actin cytoskeleton	4/2619	12/18670	0.07536	0.2224	0.1668	PFN2/BAIAP2/CYFIP1/MYH10	4
BP	GO:0150065	regulation of deacetylase activity	4/2619	12/18670	0.07536	0.2224	0.1668	KDM5A/PRKD2/PINK1/VEGFA	4
BP	GO:1900165	negative regulation of interleukin-6 secretion	4/2619	12/18670	0.07536	0.2224	0.1668	CD200/IL27RA/SYT11/PTPN22	4
BP	GO:1901387	positive regulation of voltage-gated calcium channel activity	4/2619	12/18670	0.07536	0.2224	0.1668	FGF14/EHD3/S100A1/CACNB2	4
BP	GO:1902287	semaphorin-plexin signaling pathway involved in axon guidance	4/2619	12/18670	0.07536	0.2224	0.1668	SEMA3A/SEMA3F/PLXND1/PLXNA1	4
BP	GO:1902916	positive regulation of protein polyubiquitination	4/2619	12/18670	0.07536	0.2224	0.1668	NMI/BIRC2/PTPN22/NOD2	4
BP	GO:1904181	positive regulation of membrane depolarization	4/2619	12/18670	0.07536	0.2224	0.1668	ANK3/TSPO/KDR/MYOC	4
BP	GO:2000105	positive regulation of DNA-dependent DNA replication	4/2619	12/18670	0.07536	0.2224	0.1668	CDC7/DBF4/ATRX/STOML2	4
BP	GO:2000232	regulation of rRNA processing	4/2619	12/18670	0.07536	0.2224	0.1668	HEATR1/TRMT112/WDR43/DIMT1	4
BP	GO:2001198	regulation of dendritic cell differentiation	4/2619	12/18670	0.07536	0.2224	0.1668	HLA-G/LILRB2/HMGB1/CEBPB	4
BP	GO:0050770	regulation of axonogenesis	33/2619	183/18670	0.07543	0.2225	0.1669	CDH2/UST/SEMA4D/MYCBP2/MACF1/SEMA4A/SEMA3A/FGF13/TUBB2B/CHN1/NTRK2/APOE/GSK3B/SEMA4C/EFNA5/TRAK1/SIPA1L1/SEMA3F/RND2/EPHA4/VEGFA/PLXND1/ARHGAP35/SEMA3E/CTTN/GOLGA4/NGFR/TRPV2/CDKL5/PLXNA1/CYFIP1/DSCAM/BDNF	33
BP	GO:0009746	response to hexose	36/2619	202/18670	0.07548	0.2226	0.1669	FIS1/SRI/APOM/MPC2/BAD/ANGPT2/EFNA5/CMA1/RMI1/GPER1/ARRB1/OXCT1/POLG/PTPRN2/LRP5/MAP4K4/EGR1/NAMPT/PCK2/TXN2/SLC2A5/ANO1/PPP3CA/VAMP2/LPL/HIF1A/PRKAA1/RAF1/RAB11B/TCF7L2/ENSA/XBP1/PTK2B/SERPINF1/TH/PIK3CA	36
BP	GO:0006298	mismatch repair	9/2619	38/18670	0.07576	0.2227	0.167	ERCC1/POLD2/TDG/RPA1/RPA3/POLD4/PMS2P1/HMGB1/SETD2	9
BP	GO:0007223	Wnt signaling pathway, calcium modulating pathway	9/2619	38/18670	0.07576	0.2227	0.167	WNT11/LEF1/FZD3/NLK/PPP3CA/AGO3/TCF7L2/FZD6/FZD2	9
BP	GO:0010939	regulation of necrotic cell death	9/2619	38/18670	0.07576	0.2227	0.167	BIRC3/SLC25A4/CFLAR/BIRC2/NOL3/ARHGEF2/PELI1/TSPO/CYLD	9
BP	GO:0046636	negative regulation of alpha-beta T cell activation	9/2619	38/18670	0.07576	0.2227	0.167	IL4R/RUNX3/TNFRSF14/SOCS1/HFE/RC3H2/XCL1/TNFSF4/HMGB1	9
BP	GO:0048009	insulin-like growth factor receptor signaling pathway	9/2619	38/18670	0.07576	0.2227	0.167	AR/IGFBP5/IGFBP2/IGFBP4/PHIP/IGF1/GHSR/CILP/GHR	9
BP	GO:0071604	transforming growth factor beta production	9/2619	38/18670	0.07576	0.2227	0.167	CD200/SMAD3/LTBP3/WNT11/TYROBP/XCL1/HIF1A/CREB1/ATF2	9
BP	GO:0097352	autophagosome maturation	9/2619	38/18670	0.07576	0.2227	0.167	GABARAPL1/GABARAPL2/UVRAG/ADRB2/VPS16/UBQLN4/MCOLN1/GABARAP/CLEC16A	9
BP	GO:0002011	morphogenesis of an epithelial sheet	12/2619	55/18670	0.07622	0.2237	0.1678	NOTCH1/SOS1/ADAM17/ITGA5/CD44/HBEGF/CLASP1/CD151/MMP12/ARHGAP35/PHACTR4/FLNA	12
BP	GO:0043551	regulation of phosphatidylinositol 3-kinase activity	12/2619	55/18670	0.07622	0.2237	0.1678	SOCS6/SOCS1/KIT/FGR/PIK3R5/PDGFB/CD19/CCR7/NOD2/WDR91/PTK2B/CISH	12
BP	GO:0044380	protein localization to cytoskeleton	12/2619	55/18670	0.07622	0.2237	0.1678	GSK3B/C2CD3/MAPRE3/SPAG5/BBS4/DCTN2/PCM1/GOLGB1/KIAA0753/SNX10/MAPRE2/NUP62	12
BP	GO:0022010	central nervous system myelination	6/2619	22/18670	0.07703	0.2253	0.169	CLU/ID4/ERCC2/FA2H/PLP1/TENM4	6
BP	GO:0032291	axon ensheathment in central nervous system	6/2619	22/18670	0.07703	0.2253	0.169	CLU/ID4/ERCC2/FA2H/PLP1/TENM4	6
BP	GO:0032656	regulation of interleukin-13 production	6/2619	22/18670	0.07703	0.2253	0.169	TNFRSF21/HLA-E/LEF1/IL17RB/TNFSF4/IL17RA	6
BP	GO:0044342	type B pancreatic cell proliferation	6/2619	22/18670	0.07703	0.2253	0.169	SFRP1/NUPR1/IGFBP5/BAD/IGFBP4/WDR13	6
BP	GO:0051457	maintenance of protein location in nucleus	6/2619	22/18670	0.07703	0.2253	0.169	SKP1/ARL2/BARD1/BBS4/PML/ARL2BP	6
BP	GO:1901984	negative regulation of protein acetylation	6/2619	22/18670	0.07703	0.2253	0.169	SNCA/GSK3B/SET/ZNF451/TAF7/TWIST1	6
BP	GO:2000773	negative regulation of cellular senescence	6/2619	22/18670	0.07703	0.2253	0.169	PLK2/NAMPT/MAP3K3/HMGA2/TWIST1/FBXO5	6
BP	GO:0007517	muscle organ development	68/2619	410/18670	0.07777	0.2263	0.1697	SGCA/PITX1/SIX1/CXCL10/NUPR1/NOTCH1/JARID2/SGCG/MYL6B/SRI/SMAD3/CFLAR/SGCB/FOXC1/PRR14/RBP4/PIM1/ATF3/MYOM2/RXRA/BMP4/FGF20/LEF1/MED1/GPX1/MYL3/CTF1/TAZ/LAMA5/CRYAB/S1PR1/CCNT2/RGS4/MAFF/ZFPM2/ASS1/MAPK11/CTDP1/IGF1/TBX5/CCNB1/HBEGF/EGR1/RBPJ/PIN1/PAXBP1/PPP3CA/HOXD9/COL6A3/PRKAA1/HLF/CREB1/CDK1/ID3/LUC7L/CD164/SAP30/ERBB4/EP300/XBP1/COL3A1/FZD7/SMO/CENPF/GTF3C5/TWIST1/FZD2/NR1D2	68
BP	GO:0051056	regulation of small GTPase mediated signal transduction	57/2619	338/18670	0.07796	0.2263	0.1697	NOTCH1/JAK2/ECT2/RASGRP1/SH2B2/STK19/ARHGEF3/SOS1/RALGAPB/ARHGEF40/ITSN2/ARHGEF9/CDC42SE1/RACGAP1/TIMP2/CHN1/APOE/DENND4B/MADD/RHOF/ARHGEF2/SHOC2/SIPA1L1/ARRB1/F2R/NTRK1/AUTS2/FOXM1/ARHGAP19/ARAP3/ARHGEF7/IGF1/RAC2/RASIP1/MAP4K4/SIPA1L3/MYOC/ARHGAP35/PLCE1/NET1/OGT/RAF1/TNK1/AKAP13/RHOH/EPS8L2/RALGPS2/MAPRE2/COL3A1/KRAS/GPR4/ARFGEF1/KANK2/MCF2L/ARHGAP26/NUP62/EPOR	57
BP	GO:0034113	heterotypic cell-cell adhesion	13/2619	61/18670	0.07802	0.2263	0.1697	CD200/LILRB2/PTPRC/ITGAX/ITGA5/MAPK7/ITGB7/CD44/LCK/CD58/IL1RN/CD2/CXADR	13
BP	GO:0042490	mechanoreceptor differentiation	13/2619	61/18670	0.07802	0.2263	0.1697	NOTCH1/ATP8B1/NTRK2/BMP4/FGF20/NAGLU/NTRK1/MCOLN3/RBPJ/SOD1/JAG2/SLC4A7/FZD2	13
BP	GO:0042733	embryonic digit morphogenesis	13/2619	61/18670	0.07802	0.2263	0.1697	HOXA11/NOTCH1/TMEM231/IFT52/BMP4/C2CD3/B9D1/OSR2/IFT140/HDAC1/HOXC11/FZD6/TWIST1	13
BP	GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	13/2619	61/18670	0.07802	0.2263	0.1697	RIPK2/MALT1/IL4R/RUNX3/CD83/SOCS1/RC3H2/CD81/IFNG/XCL1/TNFSF4/HMGB1/PRKCQ	13
BP	GO:0006577	amino-acid betaine metabolic process	5/2619	17/18670	0.07829	0.2263	0.1697	ALDH7A1/SLC22A4/ALDH9A1/ACADM/CRAT	5
BP	GO:0006895	Golgi to endosome transport	5/2619	17/18670	0.07829	0.2263	0.1697	VPS13C/SORT1/MON2/AP1AR/AP4M1	5
BP	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	5/2619	17/18670	0.07829	0.2263	0.1697	CHEK2/FOXM1/BRCA2/KAT5/CDKN1A	5
BP	GO:0009070	serine family amino acid biosynthetic process	5/2619	17/18670	0.07829	0.2263	0.1697	CBS/SERINC5/PSPH/SRR/SEPHS1	5
BP	GO:0016254	preassembly of GPI anchor in ER membrane	5/2619	17/18670	0.07829	0.2263	0.1697	PIGA/PIGP/PIGH/PIGZ/PIGC	5
BP	GO:0018027	peptidyl-lysine dimethylation	5/2619	17/18670	0.07829	0.2263	0.1697	KDM3A/SETMAR/SMYD2/SETD2/SUV39H2	5
BP	GO:0031643	positive regulation of myelination	5/2619	17/18670	0.07829	0.2263	0.1697	TNFRSF1B/HGF/ITGAX/CST7/TENM4	5
BP	GO:0032460	negative regulation of protein oligomerization	5/2619	17/18670	0.07829	0.2263	0.1697	CLU/CRYAB/PEX14/EP300/RIOK3	5
BP	GO:0035313	wound healing, spreading of epidermal cells	5/2619	17/18670	0.07829	0.2263	0.1697	ADAM17/ITGA5/HBEGF/CLASP1/MMP12	5
BP	GO:0035518	histone H2A monoubiquitination	5/2619	17/18670	0.07829	0.2263	0.1697	SKP1/PCGF1/DDB2/RYBP/RING1	5
BP	GO:0035855	megakaryocyte development	5/2619	17/18670	0.07829	0.2263	0.1697	KIT/MED1/ABI1/EP300/SH2B3	5
BP	GO:0043923	positive regulation by host of viral transcription	5/2619	17/18670	0.07829	0.2263	0.1697	CHD1/RRP1B/LEF1/CTDP1/EP300	5
BP	GO:0048535	lymph node development	5/2619	17/18670	0.07829	0.2263	0.1697	IL15/IL7R/TNFRSF11A/TOX/RC3H2	5
BP	GO:0051818	disruption of cells of other organism involved in symbiotic interaction	5/2619	17/18670	0.07829	0.2263	0.1697	BAD/ELANE/TUSC2/MBL2/CTSG	5
BP	GO:0055070	copper ion homeostasis	5/2619	17/18670	0.07829	0.2263	0.1697	PRNP/SCO2/SLC31A2/PRND/CUTC	5
BP	GO:0061952	midbody abscission	5/2619	17/18670	0.07829	0.2263	0.1697	CEP55/CHMP6/CHMP2A/CHMP1B/KIF20A	5
BP	GO:0072673	lamellipodium morphogenesis	5/2619	17/18670	0.07829	0.2263	0.1697	PLEKHO1/CD44/SNX2/ARHGEF7/ABI1	5
BP	GO:0099010	modification of postsynaptic structure	5/2619	17/18670	0.07829	0.2263	0.1697	PFN2/BAIAP2/CYFIP1/MYH10/STAU1	5
BP	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	5/2619	17/18670	0.07829	0.2263	0.1697	ATP2B2/CACNB2/CALB2/CACNA1D/ATP2B1	5
BP	GO:2000811	negative regulation of anoikis	5/2619	17/18670	0.07829	0.2263	0.1697	NOTCH1/ITGA5/NTRK2/MCL1/PIK3CA	5
BP	GO:2000241	regulation of reproductive process	27/2619	146/18670	0.07857	0.227	0.1703	HPGDS/CDC25B/SFRP1/NUPR1/NOTCH1/AR/SOX9/ASPM/SEMA3A/ADA/INSR/RXRA/BMP4/NPR2/ZFPM2/IGF1/CDC20/YTHDC2/RAD1/CIB1/GDF9/TIMP1/PIWIL2/INHBB/SERPINF1/DAZL/FBXO5	27
BP	GO:0051261	protein depolymerization	21/2619	109/18670	0.07892	0.2279	0.1709	MICAL1/STMN2/GAK/SH3GL1/TMOD1/FGF13/KIF2A/SYNJ1/CAPZA1/ARHGEF2/ASPH/KIF18B/MICAL2/TAOK1/TMOD2/CLASP1/SCIN/SPAST/KATNB1/CIB1/LIMA1	21
BP	GO:0048747	muscle fiber development	14/2619	67/18670	0.07924	0.2288	0.1716	SIX1/DYSF/UCHL1/SGCB/MYOM2/BMP4/GPX1/NEBL/COMP/VEGFA/CHRNB1/PPP3CA/CXADR/SMO	14
BP	GO:0033865	nucleoside bisphosphate metabolic process	26/2619	140/18670	0.07978	0.2297	0.1723	PDK2/ENPP1/SNCA/PMVK/ACSM5/MPC2/TECR/SLC25A1/ACOT13/TPST1/ACSL5/HMGCL/GSTZ1/ACAT1/DLD/SCD5/PDK1/SULT1A2/PDHB/SUCLG1/PANK3/ACOT8/FAR2/MPC1/PAPSS1/MVK	26
BP	GO:0033875	ribonucleoside bisphosphate metabolic process	26/2619	140/18670	0.07978	0.2297	0.1723	PDK2/ENPP1/SNCA/PMVK/ACSM5/MPC2/TECR/SLC25A1/ACOT13/TPST1/ACSL5/HMGCL/GSTZ1/ACAT1/DLD/SCD5/PDK1/SULT1A2/PDHB/SUCLG1/PANK3/ACOT8/FAR2/MPC1/PAPSS1/MVK	26
BP	GO:0034032	purine nucleoside bisphosphate metabolic process	26/2619	140/18670	0.07978	0.2297	0.1723	PDK2/ENPP1/SNCA/PMVK/ACSM5/MPC2/TECR/SLC25A1/ACOT13/TPST1/ACSL5/HMGCL/GSTZ1/ACAT1/DLD/SCD5/PDK1/SULT1A2/PDHB/SUCLG1/PANK3/ACOT8/FAR2/MPC1/PAPSS1/MVK	26
BP	GO:0046330	positive regulation of JNK cascade	26/2619	140/18670	0.07978	0.2297	0.1723	TPD52L1/MAP3K5/RASGRP1/RIPK2/SLAMF1/TNIK/SEMA3A/MAP3K11/TNFRSF11A/BIRC7/MAP4K1/CD27/DAXX/TAOK1/EPHA4/MFHAS1/HMGB1/CCR7/NOD2/IL1RN/TAOK3/NOD1/PTK2B/FZD7/CD40LG/NCF1	26
BP	GO:0007019	microtubule depolymerization	10/2619	44/18670	0.08001	0.2297	0.1723	STMN2/FGF13/KIF2A/ARHGEF2/KIF18B/TAOK1/CLASP1/SPAST/KATNB1/CIB1	10
BP	GO:0035850	epithelial cell differentiation involved in kidney development	10/2619	44/18670	0.08001	0.2297	0.1723	NOTCH1/STAT1/PRKX/BMP4/MAGI2/SIX2/PDGFB/SMO/GPR4/PODXL	10
BP	GO:0044060	regulation of endocrine process	10/2619	44/18670	0.08001	0.2297	0.1723	TACR2/RAB11FIP1/F2R/AGT/CRHBP/TAC1/GDF9/GAL/CRY1/INHBB	10
BP	GO:0070897	transcription preinitiation complex assembly	10/2619	44/18670	0.08001	0.2297	0.1723	ATF7IP/BRF2/PSMC2/GTF2A2/PSMC3/TAF7/HMGB1/CREB1/BAZ2A/GTF3C5	10
BP	GO:0071622	regulation of granulocyte chemotaxis	10/2619	44/18670	0.08001	0.2297	0.1723	DYSF/CCL5/MAPK3/THBS4/RAC2/XCL1/CCR7/CXCR2/MPP1/CXCL8	10
BP	GO:1902667	regulation of axon guidance	10/2619	44/18670	0.08001	0.2297	0.1723	SEMA4D/MYCBP2/SEMA4A/SEMA3A/TUBB2B/SEMA4C/SEMA3F/VEGFA/SEMA3E/DSCAM	10
BP	GO:2000404	regulation of T cell migration	10/2619	44/18670	0.08001	0.2297	0.1723	CXCL10/CD200/CCL5/IL27RA/CXCL13/ADAM17/TNFRSF14/XCL1/TNFSF14/CCR2	10
BP	GO:0044773	mitotic DNA damage checkpoint	19/2619	97/18670	0.08005	0.2297	0.1723	NBN/RFWD3/CRADD/CHEK2/ATM/DONSON/PLK2/CCNB1/TAOK1/PML/TAOK3/GTSE1/CDK1/RAD9A/CDKN1A/ATF2/EP300/HMGA2/RBL2	19
BP	GO:2001022	positive regulation of response to DNA damage stimulus	19/2619	97/18670	0.08005	0.2297	0.1723	EYA2/PARP3/SMCHD1/ATR/ATM/EGFR/DDX11/MMS19/SETMAR/FOXM1/MYC/PLA2R1/HMGB1/TIMELESS/BABAM1/CEBPG/RAD9A/ACTR2/HMGA2	19
BP	GO:0048814	regulation of dendrite morphogenesis	18/2619	91/18670	0.08038	0.2304	0.1728	SEMA4D/TNIK/SS18L1/BAIAP2/GSK3B/PARP6/SIPA1L1/YWHAH/CHRNA3/VAMP7/TLX2/EPHA4/PPP3CA/CDKL5/CAPRIN2/CAMK2B/ACTR2/NEDD4L	18
BP	GO:0031110	regulation of microtubule polymerization or depolymerization	16/2619	79/18670	0.08041	0.2304	0.1728	STMN2/SNCA/ARL2/FGF13/MAPRE3/ARHGEF2/DRG1/CDH5/TAOK1/CLASP1/SPAST/KATNB1/AKAP9/RANGRF/CIB1/MAPRE2	16
BP	GO:1903312	negative regulation of mRNA metabolic process	16/2619	79/18670	0.08041	0.2304	0.1728	HNRNPA2B1/CIRBP/BARD1/HNRNPA0/HNRNPK/SFSWAP/SRSF4/SLC11A1/MAPKAPK2/DND1/YBX1/TARDBP/MYD88/CDK9/HNRNPD/DAZL	16
BP	GO:0034308	primary alcohol metabolic process	17/2619	85/18670	0.08052	0.2304	0.1728	AKR1B1/PNPLA4/AKR1B10/ALDH1A1/DHRS3/DHRS9/RBP4/CYP11A1/AKR7A2/GDE1/IGF1/AKR1C3/SULT1A2/ALDH3A2/ALDH1A3/AKR1C4/ALDH3B1	17
BP	GO:0045682	regulation of epidermis development	17/2619	85/18670	0.08052	0.2304	0.1728	NOTCH1/FOXC1/NCOA3/EZH2/PRKCH/KRT10/BMP4/NAB1/MED1/ROCK1/MAFF/DKK4/FERMT1/GAL/HOXA7/SMO/REG3A	17
BP	GO:0050772	positive regulation of axonogenesis	17/2619	85/18670	0.08052	0.2304	0.1728	SEMA4D/MACF1/TUBB2B/NTRK2/EFNA5/TRAK1/RND2/VEGFA/PLXND1/GOLGA4/NGFR/TRPV2/CDKL5/PLXNA1/CYFIP1/DSCAM/BDNF	17
BP	GO:0032273	positive regulation of protein polymerization	25/2619	134/18670	0.08097	0.2315	0.1736	IQGAP2/ACTR3B/ARPC1A/CDC42EP3/ARL2/FCHSD2/PFN2/BAIAP2/NCK2/PINK1/ACTR3/BIN1/DRG1/CLASP1/MAGEL2/SCIN/CCR7/AP1AR/ARPC5L/AKAP9/CTTN/HIP1R/CYFIP1/PTK2B/ACTR2	25
BP	GO:0048565	digestive tract development	25/2619	134/18670	0.08097	0.2315	0.1736	SFRP1/NOTCH1/CHD8/NIPBL/SMAD3/TCF7/EGFR/ADA/KIT/BMP4/WNT11/FOXF1/ASS1/SIX2/CCNB1/CPS1/PRDM1/HIF1A/HOXA5/TYMS/ID2/CDKN1A/COL3A1/CXCL8/SMO	25
BP	GO:0110053	regulation of actin filament organization	45/2619	261/18670	0.08114	0.2318	0.1739	SFRP1/IQGAP2/ACTR3B/ARPC1A/SMAD3/TMOD1/CDC42EP3/FCHSD2/PFN2/BAIAP2/NCK2/ACTR3/CORO2B/LIMCH1/CAPZA1/BIN1/WNT11/ROCK1/BBS4/PTGER4/S1PR1/RGS4/PPM1E/TMOD2/CLASP1/FHOD3/MAGEL2/MYOC/SCIN/ARHGAP35/CCR7/AP1AR/TMSB10/ALMS1/ARPC5L/NF2/TAC1/CTTN/HIP1R/CYFIP1/LIMA1/FLNA/PTK2B/ARFGEF1/ACTR2	45
BP	GO:0006471	protein ADP-ribosylation	8/2619	33/18670	0.08144	0.2318	0.1739	PARP12/PARP3/TNKS2/PARP6/PARP8/IFNG/PARP4/KAT2B	8
BP	GO:0016242	negative regulation of macroautophagy	8/2619	33/18670	0.08144	0.2318	0.1739	NUPR1/PINK1/SEC22B/POLDIP2/UBQLN4/NPC1/CLEC16A/PIK3CA	8
BP	GO:0019692	deoxyribose phosphate metabolic process	8/2619	33/18670	0.08144	0.2318	0.1739	ADK/TDG/ADA/SAMHD1/DGUOK/GUK1/DCTD/TYMS	8
BP	GO:0030513	positive regulation of BMP signaling pathway	8/2619	33/18670	0.08144	0.2318	0.1739	NOTCH1/NEO1/BMP4/GDF5/FKBP8/CDH5/RBPJ/ZNF423	8
BP	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	8/2619	33/18670	0.08144	0.2318	0.1739	LSM4/WDR61/EXOSC7/LSM3/DCP2/LSM5/EDC4/LSM2	8
BP	GO:0045191	regulation of isotype switching	8/2619	33/18670	0.08144	0.2318	0.1739	PARP3/TFRC/IL27RA/PTPRC/THOC1/CD28/CD40/TNFSF4	8
BP	GO:0048821	erythrocyte development	8/2619	33/18670	0.08144	0.2318	0.1739	EPB42/MED1/JMJD6/PTBP3/ARID4A/ERCC2/SH2B3/TRIM58	8
BP	GO:1901890	positive regulation of cell junction assembly	8/2619	33/18670	0.08144	0.2318	0.1739	SFRP1/SMAD3/ROCK1/AGT/KDR/MAP4K4/MYOC/VEGFA	8
BP	GO:2001024	negative regulation of response to drug	8/2619	33/18670	0.08144	0.2318	0.1739	SNCA/HGF/PINK1/RGS4/TRAP1/ARL6IP5/PYCR1/PSAP	8
BP	GO:0051017	actin filament bundle assembly	28/2619	153/18670	0.08251	0.2347	0.1761	SFRP1/LCP1/SMAD3/PFN2/BAIAP2/NEDD9/CORO2B/LIMCH1/RHOF/WNT11/ROCK1/BBS4/PTGER4/ARRB1/S1PR1/PPM1E/RND2/CLASP1/MYOC/ALMS1/NF2/TAC1/ITGB5/LIMA1/ACTN1/FLNA/PTK2B/SORBS1	28
BP	GO:0010256	endomembrane system organization	72/2619	438/18670	0.08277	0.2354	0.1765	MICALL1/DYSF/AR/GAK/MAPK3/BNIP1/TMED1/CLU/VPS37C/PRKCB/SYT11/RAB27A/PTPRC/PDE4DIP/ATP8B1/MOSPD3/SYNJ1/BAIAP2/ASAP1/PRMT5/TMED3/LMAN2/BIN1/BLOC1S1/ARL1/EHD3/ANK3/GOLGA8A/UGCG/GPER1/CXCR4/CHMP6/F2R/TOR1AIP1/BANF1/ARHGEF7/CCNB2/CHMP2A/CCNB1/SEC16A/PLSCR4/CLASP1/TRAPPC8/UBL4A/CSNK1A1/USP8/ANKLE2/TMED2/OPTN/GOLGB1/SOD1/SNX10/SPAST/TMED9/TMED10/TMF1/RTN3/AKAP9/TARDBP/FA2H/CHMP1B/HOOK2/CREB1/CDK1/GOLPH3/LPIN1/ARFGEF1/PSAP/MYH10/TRAPPC11/DNAJC13/SRGN	72
BP	GO:0002931	response to ischemia	11/2619	50/18670	0.08306	0.2355	0.1767	TREM2/NDNF/MAP3K5/UCHL1/PINK1/CX3CR1/NOL3/EGR1/CASP9/P2RX4/CIB1	11
BP	GO:0045540	regulation of cholesterol biosynthetic process	11/2619	50/18670	0.08306	0.2355	0.1767	PMVK/ERLIN2/APOE/SC5D/MBTPS1/DHCR7/KPNB1/SOD1/PRKAA1/NFYC/MVK	11
BP	GO:0060976	coronary vasculature development	11/2619	50/18670	0.08306	0.2355	0.1767	NOTCH1/BMP4/GPER1/SNX17/TBX5/PRDM1/VEGFA/PLXND1/SETD2/MYH10/VEGFB	11
BP	GO:0070741	response to interleukin-6	11/2619	50/18670	0.08306	0.2355	0.1767	CEBPA/STAT1/JAK2/PID1/JAK1/PHB/PTPN2/NFKB1/IL6/IL6R/SBNO2	11
BP	GO:0086009	membrane repolarization	11/2619	50/18670	0.08306	0.2355	0.1767	SCN1B/ATP1B1/SNTA1/KCNQ1/KCNJ2/KCNJ8/KCNN2/AKAP9/CACNA1D/FLNA/NEDD4L	11
BP	GO:0106118	regulation of sterol biosynthetic process	11/2619	50/18670	0.08306	0.2355	0.1767	PMVK/ERLIN2/APOE/SC5D/MBTPS1/DHCR7/KPNB1/SOD1/PRKAA1/NFYC/MVK	11
BP	GO:0032874	positive regulation of stress-activated MAPK cascade	31/2619	172/18670	0.08316	0.2357	0.1768	TPD52L1/SPHK1/MAP3K5/RASGRP1/RIPK2/SLAMF1/TNIK/SEMA3A/MAP3K11/TNFRSF11A/BIRC7/SEMA4C/MAP4K1/CD27/DAXX/TAOK1/EPHA4/MFHAS1/VEGFA/HMGB1/CCR7/NOD2/ARL6IP5/MAP3K3/IL1RN/TAOK3/NOD1/PTK2B/FZD7/CD40LG/NCF1	31
BP	GO:0019730	antimicrobial humoral response	23/2619	122/18670	0.08322	0.2357	0.1768	CXCL9/CXCL10/CXCL13/CLU/CXCL11/SLPI/HLA-E/CXCL2/IGHM/FAM3A/ELANE/GNLY/SLC11A1/DEFA6/HMGN2/CXCL3/CCL13/CTSG/DEFA5/S100A12/CXCL8/DEFB126/REG3A	23
BP	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	23/2619	122/18670	0.08322	0.2357	0.1768	CEBPA/CLU/HERPUD1/CBFA2T3/GSK3B/CHFR/HFE/FHIT/PLK2/TRIB1/DET1/CSNK1A1/RNF19B/UBQLN4/GLMN/CSNK1E/PSMD10/OGT/RYBP/RNF14/N4BP1/CLEC16A/USP14	23
BP	GO:0006304	DNA modification	22/2619	116/18670	0.08425	0.2385	0.1789	PARP3/DNMT1/FTO/EZH2/ATF7IP/TDG/APOBEC3C/PRMT5/RLF/MPG/ASCC3/GATAD2A/MYC/APOBEC3B/ATRX/METTL4/USP9X/HEMK1/ASCC1/PIWIL2/BAZ2A/PIK3CA	22
BP	GO:0035265	organ growth	36/2619	204/18670	0.0844	0.2388	0.1791	NOTCH1/JARID2/SCARA3/AR/SOX9/WWC3/DUSP6/FOXC1/RBP4/PIM1/STC1/RXRA/FGF20/S1PR1/RGS4/ZFPM2/AGT/MAPK11/CTDP1/IGF1/COMP/TBX5/CCNB1/MMP13/RBPJ/SORBS2/PIN1/COL6A3/SOD1/MBL2/AKAP13/CDK1/ERBB4/SMO/PSAP/TENM4	36
BP	GO:0000768	syncytium formation by plasma membrane fusion	12/2619	56/18670	0.08519	0.2408	0.1806	CXCL9/CXCL10/PLEKHO1/TREM2/TCTA/IL4R/CFLAR/CD81/TYROBP/CAMK1/TNFSF14/SBNO2	12
BP	GO:0140253	cell-cell fusion	12/2619	56/18670	0.08519	0.2408	0.1806	CXCL9/CXCL10/PLEKHO1/TREM2/TCTA/IL4R/CFLAR/CD81/TYROBP/CAMK1/TNFSF14/SBNO2	12
BP	GO:0098739	import across plasma membrane	21/2619	110/18670	0.08521	0.2408	0.1806	FOLR1/ATP1B1/SLC12A8/SLC7A11/PRNP/SLC12A7/HFE/KCNJ2/FOLR2/IFNG/RGS4/SLC39A8/AGT/FAM155A/SLC2A5/CALCR/ARL6IP5/SLC39A14/KCNJ8/ATP2B4/SLC1A1	21
BP	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	69/2619	419/18670	0.08533	0.241	0.1808	CEBPA/KCTD2/FBXW7/SKP1/CLU/HERPUD1/ERLIN2/UCHL1/UBR2/PSMB9/CBFA2T3/AREL1/UBE2J1/PTTG1/GSK3B/BIRC2/CHFR/DNAJB14/HFE/BUB1B/FBXO17/PSMC2/FBXL2/LTN1/FHIT/UBXN4/ARRB1/PELI1/PLK2/PSMB6/TRIB1/ANKZF1/DET1/CCNB1/PSMC3/MAN1B1/PML/CDC20/CSNK1A1/AURKB/RNF19B/PSMD8/UBB/UBQLN4/GLMN/PSMB5/CSNK1E/RNF187/EDEM1/KAT5/UBXN8/PSMD10/OGT/RYBP/CDK1/RNF14/N4BP1/CUL2/FBXO38/TRIM2/HSPA5/SEL1L/CLEC16A/DDIT3/USP14/RNF34/NEDD4L/NEMF/FBXO5	69
BP	GO:0071824	protein-DNA complex subunit organization	49/2619	288/18670	0.08549	0.2413	0.181	CETN2/NAP1L3/SOX9/ATF7IP/BRF2/NAP1L2/SMARCD3/ORC3/RPA1/SART3/SET/RPA3/ZNHIT1/PSMC2/ARID1A/DAXX/CENPE/GTF2A2/NASP/CCNH/PSMC3/MYC/MIS12/TAF7/ATRX/PBRM1/UBB/HMGB1/HJURP/DDB2/CENPT/KAT6A/PTMA/SMARCA5/ERCC2/SMARCD2/TSPYL1/SETD2/CREB1/CENPC/MNAT1/TSPYL5/GTF2H3/BAZ2A/UBN1/HMGA1/CENPF/GTF3C5/POGZ	49
BP	GO:0046928	regulation of neurotransmitter secretion	20/2619	104/18670	0.08608	0.2429	0.1822	TACR2/SNCA/RIMS3/PREPL/PRKCB/SYT11/PFN2/MCTP1/GSK3B/GPER1/CHRNA3/SNCAIP/HCRT/ADCY1/CACNB2/CACNA1D/SYT1/SYN1/RAP1B/NAPA	20
BP	GO:0021915	neural tube development	29/2619	160/18670	0.08633	0.2432	0.1824	SFRP1/NOTCH1/FOLR1/TCTN1/TCF7/IFT52/RALA/BMP4/C2CD3/SEMA4C/FZD3/BBS4/FKBP8/ARID1A/APAF1/EN1/DEAF1/IFT140/ARHGAP35/GLMN/TMED2/PHACTR4/HIF1A/SETD2/BCL10/FZD6/SMO/TWIST1/FZD2	29
BP	GO:0048736	appendage development	32/2619	179/18670	0.08654	0.2432	0.1824	PITX1/HOXA11/NOTCH1/HOXA10/HOXC10/SOX9/TMEM231/NIPBL/SLC7A11/IFT52/BMP4/GDF5/C2CD3/PRKAB1/LEF1/MED1/ASPH/B9D1/RC3H2/OSR2/COMP/TBX5/EN1/ATRX/ZNF219/IFT140/HOXD9/HDAC1/KAT2B/HOXC11/FZD6/TWIST1	32
BP	GO:0060173	limb development	32/2619	179/18670	0.08654	0.2432	0.1824	PITX1/HOXA11/NOTCH1/HOXA10/HOXC10/SOX9/TMEM231/NIPBL/SLC7A11/IFT52/BMP4/GDF5/C2CD3/PRKAB1/LEF1/MED1/ASPH/B9D1/RC3H2/OSR2/COMP/TBX5/EN1/ATRX/ZNF219/IFT140/HOXD9/HDAC1/KAT2B/HOXC11/FZD6/TWIST1	32
BP	GO:0002260	lymphocyte homeostasis	13/2619	62/18670	0.08662	0.2432	0.1824	TNFAIP3/SH2B2/SOS1/DOCK10/ADA/TNFRSF17/TCIRG1/RC3H2/CCNB2/LAT/HIF1A/TNFSF14/BCL10	13
BP	GO:0007585	respiratory gaseous exchange	13/2619	62/18670	0.08662	0.2432	0.1824	CSF2RB/FTO/NDN/SLC5A3/COX5B/FUT8/JAG2/GAA/HOXA5/HNMT/PBX3/PASK/SFTPC	13
BP	GO:0043087	regulation of GTPase activity	78/2619	479/18670	0.08666	0.2432	0.1824	SFRP1/TBC1D9/IQGAP2/CCL5/ECT2/RASGRP1/SEMA4D/CXCL13/GIT2/CCL18/ALDH1A1/RGS1/SOS1/ARL2/EZH2/RALGAPB/DOCK10/CDC42SE1/ASAP1/RACGAP1/CHN1/NTRK2/NEDD9/GSK3B/RASGRP3/NTF3/ERBB2/EFNA5/RRP1B/HTR2B/WNT11/NUP50/DENND1B/BBS4/RABEP2/CD40/RANBP2/SIPA1L1/ARRB1/S1PR1/F2R/ACAP1/NTRK1/CCL8/RABGAP1L/ARHGAP19/ARAP3/RGS4/TBC1D16/ARHGEF7/PTPRN2/RAPGEF6/RASIP1/MAP4K4/SIPA1L3/ACAP2/XCL1/EPHA4/PLXND1/PIN1/LLGL2/ARHGAP35/CCR7/TMED2/CCL13/SOD1/NET1/RHOH/CDKL5/PLXNA1/RASAL2/CCL7/MAPRE2/RASGRP2/PTK2B/ARFGEF1/ARHGAP26/ADAP2	78
BP	GO:0071331	cellular response to hexose stimulus	25/2619	135/18670	0.0867	0.2432	0.1824	FIS1/SRI/MPC2/BAD/EFNA5/CMA1/GPER1/ARRB1/OXCT1/POLG/PTPRN2/LRP5/MAP4K4/PCK2/SLC2A5/ANO1/PPP3CA/HIF1A/PRKAA1/RAF1/RAB11B/XBP1/SERPINF1/TH/PIK3CA	25
BP	GO:0014741	negative regulation of muscle hypertrophy	9/2619	39/18670	0.08679	0.2432	0.1824	NOTCH1/JARID2/TNFRSF1B/IGFBP5/SMAD3/RGS4/CTDP1/P2RX4/ATP2B4	9
BP	GO:0050775	positive regulation of dendrite morphogenesis	9/2619	39/18670	0.08679	0.2432	0.1824	SS18L1/BAIAP2/PARP6/VAMP7/EPHA4/CDKL5/CAPRIN2/CAMK2B/ACTR2	9
BP	GO:1904591	positive regulation of protein import	9/2619	39/18670	0.08679	0.2432	0.1824	ZIC1/ECT2/SMAD3/TPR/IFNG/TARDBP/FLNA/UBR5/SMO	9
BP	GO:1905521	regulation of macrophage migration	9/2619	39/18670	0.08679	0.2432	0.1824	SLAMF8/TREM2/CD200/CCL5/MAPK3/CX3CR1/CD81/P2RX4/PTK2B	9
BP	GO:0031341	regulation of cell killing	19/2619	98/18670	0.08682	0.2432	0.1824	HLA-C/DNASE1L3/RASGRP1/HLA-F/HLA-G/MICB/IL7R/HLA-A/PTPRC/BAD/HLA-B/HLA-E/PRF1/CRTAM/IFNG/TYROBP/XCL1/ULBP2/CD59	19
BP	GO:0001773	myeloid dendritic cell activation	7/2619	28/18670	0.08711	0.2432	0.1824	SLAMF1/RELB/RBPJ/HMGB1/BATF/CD2/TSPAN32	7
BP	GO:0007205	protein kinase C-activating G protein-coupled receptor signaling pathway	7/2619	28/18670	0.08711	0.2432	0.1824	DGKA/PRKD3/HTR2B/F2R/DGKZ/HCRT/CISH	7
BP	GO:0033598	mammary gland epithelial cell proliferation	7/2619	28/18670	0.08711	0.2432	0.1824	MED1/GPX1/BRCA2/DEAF1/HOXA5/ID2/CEBPB	7
BP	GO:0034368	protein-lipid complex remodeling	7/2619	28/18670	0.08711	0.2432	0.1824	LIPC/APOM/APOE/PLA2G7/APOC1/AGT/LPL	7
BP	GO:0034369	plasma lipoprotein particle remodeling	7/2619	28/18670	0.08711	0.2432	0.1824	LIPC/APOM/APOE/PLA2G7/APOC1/AGT/LPL	7
BP	GO:0036296	response to increased oxygen levels	7/2619	28/18670	0.08711	0.2432	0.1824	ATP6V0D1/FAS/CDK4/PPARG/CAT/POLG/CDKN1A	7
BP	GO:0043501	skeletal muscle adaptation	7/2619	28/18670	0.08711	0.2432	0.1824	IGFBP5/IL15/CFLAR/GTF2IRD1/MYOC/PPP3CA/CAMK2B	7
BP	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway	7/2619	28/18670	0.08711	0.2432	0.1824	GBP1/BTN2A2/PRNP/PTPN22/PTPN2/LGALS3/LPXN	7
BP	GO:0051123	RNA polymerase II preinitiation complex assembly	7/2619	28/18670	0.08711	0.2432	0.1824	ATF7IP/PSMC2/GTF2A2/PSMC3/TAF7/HMGB1/CREB1	7
BP	GO:0051647	nucleus localization	7/2619	28/18670	0.08711	0.2432	0.1824	CLMN/SYNE2/BIN1/PCM1/DYNC1H1/MYH10/TRIM58	7
BP	GO:0051984	positive regulation of chromosome segregation	7/2619	28/18670	0.08711	0.2432	0.1824	SMC6/NIPBL/DLGAP5/DDX11/SMC5/CCNB1/SFPQ	7
BP	GO:0090344	negative regulation of cell aging	7/2619	28/18670	0.08711	0.2432	0.1824	FOXM1/PLK2/NAMPT/MAP3K3/HMGA2/TWIST1/FBXO5	7
BP	GO:0006470	protein dephosphorylation	54/2619	321/18670	0.08714	0.2432	0.1824	PTPRE/CDC25B/DUSP5/PTN/EYA2/PPP1R3C/JAK2/DAPP1/DUSP6/CAMTA1/LILRB2/MTMR4/PTPRF/PTPRC/DLGAP5/PINK1/GSK3B/PTPN7/PPP6R3/SET/CTDSPL/RNGTT/MAGI2/MTMR6/PTPN22/ROCK1/SHOC2/PPP4R1/CDC14A/PPP1R16B/PTPN2/SSH3/CDH5/PPP1R12A/LCK/PPM1E/PTPRN2/CTDP1/MTMR1/DUSP2/MFHAS1/PIN1/ANKLE2/PPP3CA/PPM1B/PTPRK/ACP1/PHACTR4/ENSA/LGALS3/PTPRH/PHLPP1/STYXL1/PPA2	54
BP	GO:0070085	glycosylation	46/2619	269/18670	0.08734	0.2436	0.1827	MGAT4C/GALNT11/GALNT10/SDF2/IL15/EOGT/MPI/B4GALT2/UBE2J1/EXT2/TMEM258/B3GALNT1/FUT1/DPM3/TRAK1/RFNG/GCNT3/DPY19L2P2/DPAGT1/ST3GAL2/POFUT1/EXTL2/DAD1/MAN1C1/B4GALT7/TMEM59/MAN1B1/GALNT3/DHDDS/FUT8/DDOST/ALG6/OGT/MUC5AC/PIGZ/PMM1/ABO/ST8SIA2/ASGR1/FUT4/NPC1/C1GALT1C1/ARFGEF1/LMF1/VEGFB/B4GALT3	46
BP	GO:0006672	ceramide metabolic process	18/2619	92/18670	0.08742	0.2437	0.1828	SPHK1/PLA2G15/CERS6/ASAH1/CERS4/UGCG/CLN6/CERS2/GM2A/NEU1/SGMS1/PRKAA1/FA2H/ST8SIA2/SGPL1/PSAP/CERK/B4GALT3	18
BP	GO:0033627	cell adhesion mediated by integrin	14/2619	68/18670	0.0875	0.2439	0.1829	CCL5/CXCL13/ITGBL1/ADAM17/ITGA5/SERPINE1/ADA/ITGB7/CD3E/FERMT1/CIB1/ITGB5/PODXL/LPXN	14
BP	GO:0050710	negative regulation of cytokine secretion	15/2619	74/18670	0.08794	0.2446	0.1835	TNFAIP3/GBP1/CD200/BTN2A2/IL27RA/ANGPT1/SYT11/TNFRSF21/CARD8/PTPN22/PTGER4/GHSR/PML/TLR8/SRGN	15
BP	GO:0072078	nephron tubule morphogenesis	15/2619	74/18670	0.08794	0.2446	0.1835	SIX1/HOXA11/SOX9/PGF/CTNNBIP1/BMP4/WNT11/KLHL3/LAMA5/AGT/SIX2/MYC/VEGFA/MAGED1/SMO	15
BP	GO:1900006	positive regulation of dendrite development	15/2619	74/18670	0.08794	0.2446	0.1835	PTN/SS18L1/EZH2/BAIAP2/APOE/PARP6/VAMP7/EPHA4/CAMK1/CDKL5/CYFIP1/CAPRIN2/C21orf91/CAMK2B/ACTR2	15
BP	GO:1901616	organic hydroxy compound catabolic process	15/2619	74/18670	0.08794	0.2446	0.1835	FAH/DIO3/AKR1B10/SYNJ1/COMT/APOE/SORD/GK/MOXD1/SNX17/AKR1C3/SULT1A2/DIO2/INPP5E/ALDH3B1	15
BP	GO:0022617	extracellular matrix disassembly	16/2619	80/18670	0.08803	0.2448	0.1836	TPSAB1/LCP1/BSG/TIMP2/CAPNS1/HTRA1/CMA1/CD44/ELANE/IL6/MMP13/CLASP1/MMP12/MMP20/CTSG/TIMP1	16
BP	GO:0018022	peptidyl-lysine methylation	24/2619	129/18670	0.08805	0.2448	0.1836	MTF2/JARID2/SUZ12/WDR61/DNMT1/EZH2/ARID4B/METTL22/RLF/SETD5/KDM3A/SETMAR/SMYD2/AUTS2/WDR5B/SETD1B/ATRX/VCPKMT/EED/ARID4A/OGT/SETD2/SUV39H2/CXXC1	24
BP	GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	31/2619	173/18670	0.08827	0.2452	0.1839	TPD52L1/SPHK1/MAP3K5/RASGRP1/RIPK2/SLAMF1/TNIK/SEMA3A/MAP3K11/TNFRSF11A/BIRC7/SEMA4C/MAP4K1/CD27/DAXX/TAOK1/EPHA4/MFHAS1/VEGFA/HMGB1/CCR7/NOD2/ARL6IP5/MAP3K3/IL1RN/TAOK3/NOD1/PTK2B/FZD7/CD40LG/NCF1	31
BP	GO:0035107	appendage morphogenesis	27/2619	148/18670	0.08952	0.2485	0.1864	PITX1/HOXA11/NOTCH1/HOXA10/HOXC10/SOX9/TMEM231/NIPBL/IFT52/BMP4/GDF5/C2CD3/LEF1/MED1/ASPH/B9D1/OSR2/TBX5/EN1/ATRX/ZNF219/IFT140/HOXD9/HDAC1/HOXC11/FZD6/TWIST1	27
BP	GO:0035108	limb morphogenesis	27/2619	148/18670	0.08952	0.2485	0.1864	PITX1/HOXA11/NOTCH1/HOXA10/HOXC10/SOX9/TMEM231/NIPBL/IFT52/BMP4/GDF5/C2CD3/LEF1/MED1/ASPH/B9D1/OSR2/TBX5/EN1/ATRX/ZNF219/IFT140/HOXD9/HDAC1/HOXC11/FZD6/TWIST1	27
BP	GO:1901568	fatty acid derivative metabolic process	30/2619	167/18670	0.09002	0.2498	0.1873	HPGDS/LTC4S/PTGS1/TBXAS1/MAPK3/ALOX5AP/EPHX2/TECR/CES2/SLC25A1/BDH2/ACSL5/SLC27A5/MGST3/HMGCL/HPGD/GPX1/GPX4/PLA2G4C/OXCT1/ACAT1/ABCC1/SCD5/AKR1C3/PTGDS/MAPKAPK2/ACOX1/FAR2/CBR1/AKR1C4	30
BP	GO:0002833	positive regulation of response to biotic stimulus	10/2619	45/18670	0.09054	0.251	0.1883	MAPK3/RIPK2/TBK1/PUM2/CRTAM/LY86/OPTN/DDX60/NOD1/FBXO38	10
BP	GO:0048255	mRNA stabilization	10/2619	45/18670	0.09054	0.251	0.1883	CIRBP/HNRNPA0/SLC11A1/MAPKAPK2/DND1/YBX1/TARDBP/MYD88/HNRNPD/DAZL	10
BP	GO:0010906	regulation of glucose metabolic process	22/2619	117/18670	0.09063	0.2511	0.1884	SIK1/PDK2/ENPP1/RORA/BAD/GSK3B/INSR/IGFBP4/DYRK2/LCMT1/RANBP2/FAM3A/PTPN2/IGF1/PDK1/NFE2L1/OGT/KAT2B/EP300/CRY1/PASK/SORBS1	22
BP	GO:0007030	Golgi organization	26/2619	142/18670	0.09111	0.2523	0.1892	GAK/MAPK3/TMED1/PDE4DIP/ATP8B1/PRMT5/TMED3/LMAN2/ARL1/EHD3/GOLGA8A/ARHGEF7/SEC16A/CLASP1/TRAPPC8/CSNK1A1/TMED2/OPTN/GOLGB1/TMED9/TMED10/AKAP9/CDK1/GOLPH3/ARFGEF1/TRAPPC11	26
BP	GO:1902904	negative regulation of supramolecular fiber organization	26/2619	142/18670	0.09111	0.2523	0.1892	STMN2/SNCA/CLU/TMOD1/FGF13/PFN2/APOE/CORO2B/CAPZA1/ARHGEF2/BBS4/CRYAB/S1PR1/CDH5/TAOK1/TMOD2/CLASP1/FHOD3/MYOC/SCIN/TMSB10/KATNB1/CIB1/HIP1R/LIMA1/ARFGEF1	26
BP	GO:0050890	cognition	50/2619	296/18670	0.09143	0.253	0.1898	BRINP1/PTN/LGMN/GPR88/TACR2/NIPBL/LILRB2/SLC7A11/FGF13/B4GALT2/EGFR/SYNJ1/ITGA5/COMT/PRNP/CX3CR1/NTRK2/APOE/INSR/NTF3/KIT/HRH3/BBS4/NTRK1/PLK2/GATM/AGT/KLK8/CRHBP/TMOD2/GHSR/ADCY1/EN1/GM2A/ATP8A1/DEAF1/NRGN/HIF1A/TAC1/CREB1/VDAC3/GALR3/CYFIP1/EP300/KRAS/CEBPB/SERPINF1/ACTR2/BDNF/TH	50
BP	GO:0045165	cell fate commitment	46/2619	270/18670	0.09152	0.2532	0.1899	SLAMF8/PITX1/SIX1/HOXA11/SFRP1/NOTCH1/EYA2/WNT5B/AR/HOXC10/GAS1/SOX9/RORA/FGF13/NOTCH4/BCL11B/BMP4/WNT11/ARHGEF2/PPARG/FKBP8/EVX1/SIX2/LY9/TBX5/MGA/IL6/PML/RBPJ/PRDM1/BATF/MCL1/NFE2L1/JAG2/CYLD/TCF3/OLIG2/ID2/TCF7L2/ERBB4/ETS2/FZD7/CEBPB/SMO/TENM4/SATB2	46
BP	GO:1905330	regulation of morphogenesis of an epithelium	32/2619	180/18670	0.09169	0.2533	0.19	SIX1/SFRP1/CXCL10/AR/STAT1/SOX9/PSMB9/HGF/ITGAX/AP2M1/RXRA/BMP4/WNT11/PLEKHA4/MAGI2/PSMC2/FZD3/PSMB6/AGT/SIX2/PSMC3/CLASP1/VEGFA/PSMD8/MAGED1/PSMB5/PSMD10/FKBPL/FZD6/FZD7/SMO/FZD2	32
BP	GO:0006406	mRNA export from nucleus	21/2619	111/18670	0.09183	0.2533	0.19	HNRNPA2B1/NXF3/NUP160/THOC2/NUP153/DDX39A/THOC1/TPR/NUP50/SEC13/RANBP2/NXF1/SRSF4/NUP210/NUP43/NDC1/SETD2/YTHDC1/NCBP2/NUP98/NUP62	21
BP	GO:0022037	metencephalon development	21/2619	111/18670	0.09183	0.2533	0.19	PTN/RORA/FOXC1/SDF4/EZH2/B4GALT2/AGTPBP1/ZNF365/SEMA4C/HERC1/NAGLU/MYO16/CD3E/EN1/PTBP2/UQCRQ/HNRNPD/SEZ6L/SMO/HSPA5/MYH10	21
BP	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus	21/2619	111/18670	0.09183	0.2533	0.19	HNRNPA2B1/NXF3/NUP160/THOC2/NUP153/DDX39A/THOC1/TPR/NUP50/SEC13/RANBP2/NXF1/SRSF4/NUP210/NUP43/NDC1/SETD2/YTHDC1/NCBP2/NUP98/NUP62	21
BP	GO:1904062	regulation of cation transmembrane transport	57/2619	342/18670	0.09226	0.2533	0.19	CXCL9/DYSF/CXCL10/SCN1B/ATP1B1/TREM2/SNTA1/FXYD1/PLCG2/SNCA/SRI/KCNQ1/CXCL11/FGF14/FXYD6/NETO2/PRNP/PINK1/BIN1/EHD3/KLHL24/KCNJ2/ANK3/GRIA2/GPER1/TSPAN13/TCIRG1/F2R/ADRB2/YWHAH/IFNG/RGS4/CD63/AGT/CRHBP/S100A1/SLC31A2/XCL1/CD19/CALCR/VAMP2/CACNB2/REM1/KCNN2/LIME1/AKAP9/RANGRF/ATP2B4/CACNA1D/GAL/HSPA2/FLNA/PTK2B/CCR2/TWIST1/NEDD4L/DPP6	57
BP	GO:0000715	nucleotide-excision repair, DNA damage recognition	6/2619	23/18670	0.09238	0.2533	0.19	CETN2/COPS6/COPS7A/COPS8/UBB/DDB2	6
BP	GO:0006297	nucleotide-excision repair, DNA gap filling	6/2619	23/18670	0.09238	0.2533	0.19	POLD2/RPA1/RPA3/POLD4/UBB/RFC2	6
BP	GO:0009147	pyrimidine nucleoside triphosphate metabolic process	6/2619	23/18670	0.09238	0.2533	0.19	NME4/NME7/NME5/NME3/CTPS1/TYMS	6
BP	GO:0016578	histone deubiquitination	6/2619	23/18670	0.09238	0.2533	0.19	ATXN7/USP3/SART3/TAF10/TRRAP/USP21	6
BP	GO:0032799	low-density lipoprotein receptor particle metabolic process	6/2619	23/18670	0.09238	0.2533	0.19	SEC24A/APOE/AP2M1/CNPY2/HNRNPK/PPARG	6
BP	GO:0035561	regulation of chromatin binding	6/2619	23/18670	0.09238	0.2533	0.19	BTAF1/TDG/DDX11/HMBOX1/PPP3CA/MEPCE	6
BP	GO:0042401	cellular biogenic amine biosynthetic process	6/2619	23/18670	0.09238	0.2533	0.19	AGMAT/SMS/MOXD1/HDC/SRM/OAZ3	6
BP	GO:0042454	ribonucleoside catabolic process	6/2619	23/18670	0.09238	0.2533	0.19	ENTPD4/ADA/APOBEC3C/PNP/APOBEC3B/AHCY	6
BP	GO:0045821	positive regulation of glycolytic process	6/2619	23/18670	0.09238	0.2533	0.19	INSR/PFKFB3/IFNG/IGF1/HIF1A/PRKAA1	6
BP	GO:0051004	regulation of lipoprotein lipase activity	6/2619	23/18670	0.09238	0.2533	0.19	LIPC/APOC1/NR1H2/SORT1/LPL/LMF1	6
BP	GO:0051589	negative regulation of neurotransmitter transport	6/2619	23/18670	0.09238	0.2533	0.19	SNCA/SYT11/HRH3/RGS4/ARL6IP5/RAP1B	6
BP	GO:0071157	negative regulation of cell cycle arrest	6/2619	23/18670	0.09238	0.2533	0.19	CHEK2/CDK4/GPER1/SETMAR/CCNK/CDK9	6
BP	GO:0072337	modified amino acid transport	6/2619	23/18670	0.09238	0.2533	0.19	FOLR1/SLC22A4/SLC7A11/SLC38A2/FOLR2/ABCC1	6
BP	GO:0086012	membrane depolarization during cardiac muscle cell action potential	6/2619	23/18670	0.09238	0.2533	0.19	SCN1B/KCNJ2/ANK3/CACNB2/RANGRF/CACNA1D	6
BP	GO:1903861	positive regulation of dendrite extension	6/2619	23/18670	0.09238	0.2533	0.19	ITSN2/CXCR4/SYT17/SYT1/CPNE6/NEDD4L	6
BP	GO:0001649	osteoblast differentiation	39/2619	225/18670	0.09268	0.254	0.1905	SFRP1/NOTCH1/CEBPA/NELL1/IGFBP5/SEMA4D/ADAR/SMAD3/ATRAID/MRC2/HGF/PTH1R/CTNNBIP1/BMP4/PENK/WNT11/LEF1/PSMC2/PHB/CAT/TCIRG1/ID4/LRP5/IGF1/IL6/MYOC/SUCO/DDX21/IL6R/ID2/ID3/VCAN/CEBPB/SMO/GDPD2/TWIST1/SATB2/DNAJC13/FBXO5	39
BP	GO:0071326	cellular response to monosaccharide stimulus	25/2619	136/18670	0.0927	0.254	0.1905	FIS1/SRI/MPC2/BAD/EFNA5/CMA1/GPER1/ARRB1/OXCT1/POLG/PTPRN2/LRP5/MAP4K4/PCK2/SLC2A5/ANO1/PPP3CA/HIF1A/PRKAA1/RAF1/RAB11B/XBP1/SERPINF1/TH/PIK3CA	25
BP	GO:0002708	positive regulation of lymphocyte mediated immunity	20/2619	105/18670	0.09295	0.2544	0.1908	HLA-C/RASGRP1/TFRC/MALT1/HLA-F/HLA-G/MICB/HLA-A/PTPRC/HLA-B/HLA-E/CD28/CRTAM/CD40/CD81/IL6/XCL1/TNFSF4/ULBP2/FBXO38	20
BP	GO:0006641	triglyceride metabolic process	20/2619	105/18670	0.09295	0.2544	0.1908	PNPLA4/SIK1/LIPC/FBXW7/SLC22A4/APOE/SLC27A5/GK/GPX1/CAT/APOC1/NR1H2/CPS1/PCK2/LPL/FABP7/FABP3/LPIN1/SEL1L/LMF1	20
BP	GO:0021537	telencephalon development	43/2619	251/18670	0.09348	0.2558	0.1918	TCTN1/CDH2/NDE1/ASPM/SLC7A11/BCL2A1/SEMA3A/EZH2/SYNE2/FGF13/BAD/AGTPBP1/SLC38A2/EGFR/NTRK2/GSK3B/BCL11B/BMP4/LEF1/GNG12/BBS4/CXCR4/ID4/ALDH1A3/TSKU/TACC2/NRGN/HIF1A/HDAC1/NF2/UQCRQ/ATP2B4/SIX3/TACC3/ID2/TMEM14B/ERBB4/COL3A1/FLNA/SMO/EMX2/MYH10/TH	43
BP	GO:0034330	cell junction organization	49/2619	290/18670	0.09356	0.2558	0.1918	SFRP1/CDH2/ECT2/TRIP6/MACF1/SMAD3/MICALL2/ARL2/ITGA5/PRKCH/CORO2B/LIMCH1/PECAM1/CAPZA1/EFNA5/WNT11/ROCK1/LAMA5/F2R/FERMT2/CDH5/KRT14/ARHGEF7/AGT/PRKCI/RAB13/KDR/MAP4K4/ANG/CLASP1/CD151/MYOC/MTDH/VEGFA/TNS1/CADM3/PTPRK/CDH12/LSR/NF2/TLN2/CTTN/CXADR/MAPRE2/ACTN1/FLNA/PTK2B/RAP1B/SORBS1	49
BP	GO:1901861	regulation of muscle tissue development	28/2619	155/18670	0.09357	0.2558	0.1918	SIX1/NOTCH1/JARID2/IGFBP5/SMAD3/RBP4/PIM1/BMP4/FGF20/LEF1/RGS4/ZFPM2/MAPK11/CTDP1/IGF1/TBX5/CCNB1/RBPJ/PIN1/PRKAA1/CREB1/CDK1/LUC7L/ERBB4/FZD7/CENPF/TWIST1/NR1D2	28
BP	GO:1901570	fatty acid derivative biosynthetic process	19/2619	99/18670	0.09396	0.2563	0.1923	HPGDS/LTC4S/PTGS1/TBXAS1/ALOX5AP/TECR/SLC25A1/BDH2/ACSL5/SLC27A5/MGST3/HMGCL/HPGD/ACAT1/SCD5/AKR1C3/PTGDS/FAR2/CBR1	19
BP	GO:0032148	activation of protein kinase B activity	8/2619	34/18670	0.09401	0.2563	0.1923	PINK1/INSR/NTF3/OSBPL8/IGF1/ANG/PDGFB/MLST8	8
BP	GO:0032212	positive regulation of telomere maintenance via telomerase	8/2619	34/18670	0.09401	0.2563	0.1923	MAPK3/ATR/TNKS2/ATM/HMBOX1/AURKB/HNRNPA1/PRKCQ	8
BP	GO:0042558	pteridine-containing compound metabolic process	8/2619	34/18670	0.09401	0.2563	0.1923	GCH1/FOLR1/MTHFD2/QDPR/PCBD1/GGH/FOLR2/TYMS	8
BP	GO:0043094	cellular metabolic compound salvage	8/2619	34/18670	0.09401	0.2563	0.1923	TK2/BHMT2/ADK/ADA/DGUOK/TYMP/PNP/AMPD3	8
BP	GO:0043276	anoikis	8/2619	34/18670	0.09401	0.2563	0.1923	SIK1/NOTCH1/CHEK2/ITGA5/NTRK2/MCL1/IKBKG/PIK3CA	8
BP	GO:0009952	anterior/posterior pattern specification	38/2619	219/18670	0.09477	0.2578	0.1934	HOXA11/SFRP1/NOTCH1/HOXA10/HOXC10/SMAD3/FOXC1/MEOX1/NLE1/ATM/CTNNBIP1/BMP4/HOXB6/LEF1/HOXA4/FOXF1/POFUT1/WLS/LRP5/SIX2/RBPJ/EN1/HOXB5/TMED2/HOXD9/ABI1/HOXA5/BPTF/SIX3/HOXC11/RING1/EP300/ETS2/HOXA7/SMO/EMX2/PBX3/DDIT3	38
BP	GO:0002066	columnar/cuboidal epithelial cell development	12/2619	57/18670	0.09479	0.2578	0.1934	BAD/GSK3B/BMP4/INSM1/PRDM1/SOD1/HIF1A/HOXA5/TYMS/CDKN1A/SLC4A7/SMO	12
BP	GO:0018208	peptidyl-proline modification	12/2619	57/18670	0.09479	0.2578	0.1934	P4HTM/PPIC/FKBP8/RANBP2/CRTAP/NKTR/PIN1/FKBP10/EGLN3/PPIE/PPIB/PPIH	12
BP	GO:0042743	hydrogen peroxide metabolic process	12/2619	57/18670	0.09479	0.2578	0.1934	SNCA/EGFR/PINK1/GPX3/PRDX6/PXDN/GPX1/CAT/RAC2/SOD1/HBB/PRDX2	12
BP	GO:0060043	regulation of cardiac muscle cell proliferation	12/2619	57/18670	0.09479	0.2578	0.1934	NOTCH1/JARID2/RBP4/PIM1/FGF20/ZFPM2/MAPK11/TBX5/CCNB1/RBPJ/CDK1/ERBB4	12
BP	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	18/2619	93/18670	0.09485	0.2578	0.1934	TOPBP1/SKP1/NBN/PSMB9/ATM/PSMC2/USP47/DONSON/PSMB6/PSMC3/TAOK1/AURKB/PSMD8/PSMB5/PSMD10/TAOK3/CDK1/HMGA2	18
BP	GO:0072080	nephron tubule development	18/2619	93/18670	0.09485	0.2578	0.1934	SIX1/HOXA11/NOTCH1/STAT1/SOX9/PGF/CTNNBIP1/BMP4/WNT11/KLHL3/LAMA5/ACAT1/AGT/SIX2/MYC/VEGFA/MAGED1/SMO	18
BP	GO:0048167	regulation of synaptic plasticity	33/2619	187/18670	0.095	0.2581	0.1936	PTN/LGMN/SNCA/RIMS3/ABHD6/LILRB2/CD38/FGF14/PRNP/BAIAP2/MCTP1/CX3CR1/NTRK2/APOE/GSK3B/KIT/SIPA1L1/YWHAH/PLK2/AGT/ADCY1/CDC20/TYROBP/EPHA4/VAMP2/NRGN/CALB2/CREB1/NCDN/KRAS/PTK2B/CAMK2B/STAU1	33
BP	GO:2000058	regulation of ubiquitin-dependent protein catabolic process	27/2619	149/18670	0.09536	0.2583	0.1938	CEBPA/FBXW7/CLU/HERPUD1/CBFA2T3/EGF/GSK3B/CHFR/HFE/FHIT/PLK2/TRIB1/DET1/PML/CSNK1A1/RNF19B/UBQLN4/GLMN/CSNK1E/PSMD10/OGT/RYBP/RNF14/N4BP1/PTK2B/CLEC16A/USP14	27
BP	GO:1990138	neuron projection extension	30/2619	168/18670	0.09551	0.2583	0.1938	SEMA4D/MACF1/SEMA4A/SEMA3A/SPG11/ITSN2/NDN/APOE/GSK3B/SEMA4C/CYFIP2/CXCR4/SYT17/AUTS2/POSTN/SEMA3F/VEGFA/SEMA3E/USP9X/CTTN/GOLGA4/TRPV2/CDKL5/PLXNA1/SYT1/CYFIP1/DSCAM/CPNE6/BCL11A/NEDD4L	30
BP	GO:0007062	sister chromatid cohesion	13/2619	63/18670	0.0958	0.2583	0.1938	FBXW7/NIPBL/DDX11/BUB1B/SMC5/NAA50/CDC20/ATRX/RAD51C/MCMBP/SFPQ/SMC1A/POGZ	13
BP	GO:0090181	regulation of cholesterol metabolic process	13/2619	63/18670	0.0958	0.2583	0.1938	PMVK/EPHX2/ERLIN2/APOE/SC5D/MBTPS1/DHCR7/KPNB1/SOD1/PRKAA1/NFYC/LMF1/MVK	13
BP	GO:0070227	lymphocyte apoptotic process	14/2619	69/18670	0.09628	0.2583	0.1938	CCL5/IL7R/TNFRSF21/IDO1/ADA/BIRC7/BMP4/CD27/AURKB/PRKCQ/HIF1A/LGALS3/BCL10/CD3G	14
BP	GO:0071300	cellular response to retinoic acid	14/2619	69/18670	0.09628	0.2583	0.1938	BRINP1/SETX/WNT5B/SOX9/BRINP3/NDUFA13/ATM/WNT11/PPARG/BRINP2/CREB1/PTK2B/FZD7/SERPINF1	14
BP	GO:0006695	cholesterol biosynthetic process	15/2619	75/18670	0.09634	0.2583	0.1938	LBR/PMVK/ERLIN2/APOE/SC5D/MBTPS1/DHCR24/DHCR7/KPNB1/SOD1/PRKAA1/CYB5R3/ACAA2/NFYC/MVK	15
BP	GO:0001911	negative regulation of leukocyte mediated cytotoxicity	5/2619	18/18670	0.0964	0.2583	0.1938	HLA-F/HLA-G/IL7R/PTPRC/HLA-E	5
BP	GO:0006349	regulation of gene expression by genetic imprinting	5/2619	18/18670	0.0964	0.2583	0.1938	DIRAS3/KCNQ1/ARID4B/EED/ARID4A	5
BP	GO:0006607	NLS-bearing protein import into nucleus	5/2619	18/18670	0.0964	0.2583	0.1938	KPNA2/RANBP2/CBLB/KPNA1/KPNA3	5
BP	GO:0009084	glutamine family amino acid biosynthetic process	5/2619	18/18670	0.0964	0.2583	0.1938	ASS1/CPS1/OAT/PYCR1/ALDH18A1	5
BP	GO:0010832	negative regulation of myotube differentiation	5/2619	18/18670	0.0964	0.2583	0.1938	CXCL10/NOTCH1/CFLAR/XBP1/BDNF	5
BP	GO:0034375	high-density lipoprotein particle remodeling	5/2619	18/18670	0.0964	0.2583	0.1938	LIPC/APOM/APOE/APOC1/LPL	5
BP	GO:0042772	DNA damage response, signal transduction resulting in transcription	5/2619	18/18670	0.0964	0.2583	0.1938	CHEK2/FOXM1/BRCA2/KAT5/CDKN1A	5
BP	GO:0044320	cellular response to leptin stimulus	5/2619	18/18670	0.0964	0.2583	0.1938	CCNA2/PID1/BBS4/UGCG/INHBB	5
BP	GO:0045780	positive regulation of bone resorption	5/2619	18/18670	0.0964	0.2583	0.1938	TFRC/EGFR/LTBP3/TNFRSF11A/CA2	5
BP	GO:0046852	positive regulation of bone remodeling	5/2619	18/18670	0.0964	0.2583	0.1938	TFRC/EGFR/LTBP3/TNFRSF11A/CA2	5
BP	GO:0048557	embryonic digestive tract morphogenesis	5/2619	18/18670	0.0964	0.2583	0.1938	NIPBL/TCF7/FOXF1/SIX2/ID2	5
BP	GO:0072077	renal vesicle morphogenesis	5/2619	18/18670	0.0964	0.2583	0.1938	STAT1/SOX9/BMP4/SIX2/SMO	5
BP	GO:0150079	negative regulation of neuroinflammatory response	5/2619	18/18670	0.0964	0.2583	0.1938	CD200/TNFRSF1B/PTPRC/IGF1/CST7	5
BP	GO:2000757	negative regulation of peptidyl-lysine acetylation	5/2619	18/18670	0.0964	0.2583	0.1938	SNCA/SET/ZNF451/TAF7/TWIST1	5
BP	GO:0000212	meiotic spindle organization	4/2619	13/18670	0.09721	0.2583	0.1938	TUBG2/ASPM/ATRX/FBXO5	4
BP	GO:0001867	complement activation, lectin pathway	4/2619	13/18670	0.09721	0.2583	0.1938	SCARA3/MBL2/FCN1/KRT1	4
BP	GO:0001886	endothelial cell morphogenesis	4/2619	13/18670	0.09721	0.2583	0.1938	NOTCH4/STC1/PECAM1/TNMD	4
BP	GO:0002281	macrophage activation involved in immune response	4/2619	13/18670	0.09721	0.2583	0.1938	DYSF/TREM2/TYROBP/SBNO2	4
BP	GO:0006596	polyamine biosynthetic process	4/2619	13/18670	0.09721	0.2583	0.1938	AGMAT/SMS/SRM/OAZ3	4
BP	GO:0009437	carnitine metabolic process	4/2619	13/18670	0.09721	0.2583	0.1938	SLC22A4/ALDH9A1/ACADM/CRAT	4
BP	GO:0019896	axonal transport of mitochondrion	4/2619	13/18670	0.09721	0.2583	0.1938	UCHL1/TRAK1/SPAST/HIF1A	4
BP	GO:0021794	thalamus development	4/2619	13/18670	0.09721	0.2583	0.1938	PTN/UQCRQ/OLIG2/SMO	4
BP	GO:0030656	regulation of vitamin metabolic process	4/2619	13/18670	0.09721	0.2583	0.1938	CD320/NFKB1/IFNG/AKR1C3	4
BP	GO:0034214	protein hexamerization	4/2619	13/18670	0.09721	0.2583	0.1938	OAT/SPAST/YME1L1/LETM1	4
BP	GO:0034374	low-density lipoprotein particle remodeling	4/2619	13/18670	0.09721	0.2583	0.1938	LIPC/APOE/PLA2G7/AGT	4
BP	GO:0035745	T-helper 2 cell cytokine production	4/2619	13/18670	0.09721	0.2583	0.1938	DENND1B/CD81/IL6/XCL1	4
BP	GO:0042178	xenobiotic catabolic process	4/2619	13/18670	0.09721	0.2583	0.1938	GSTM4/GSTM5/CRYZ/GSTM3	4
BP	GO:0042415	norepinephrine metabolic process	4/2619	13/18670	0.09721	0.2583	0.1938	AKR1B1/MOXD1/INSM1/TH	4
BP	GO:0043301	negative regulation of leukocyte degranulation	4/2619	13/18670	0.09721	0.2583	0.1938	HLA-F/FOXF1/IL13RA2/CCR2	4
BP	GO:0045779	negative regulation of bone resorption	4/2619	13/18670	0.09721	0.2583	0.1938	TNFAIP3/TNFRSF11B/CD38/IL6	4
BP	GO:0046831	regulation of RNA export from nucleus	4/2619	13/18670	0.09721	0.2583	0.1938	NUP153/TPR/SETD2/NCBP2	4
BP	GO:0048291	isotype switching to IgG isotypes	4/2619	13/18670	0.09721	0.2583	0.1938	IL27RA/PTPRC/CD28/CD40	4
BP	GO:0048681	negative regulation of axon regeneration	4/2619	13/18670	0.09721	0.2583	0.1938	CERS2/KLK8/EPHA4/LRIG2	4
BP	GO:0050722	regulation of interleukin-1 beta biosynthetic process	4/2619	13/18670	0.09721	0.2583	0.1938	JAK2/IFNG/EGR1/TYROBP	4
BP	GO:0051315	attachment of mitotic spindle microtubules to kinetochore	4/2619	13/18670	0.09721	0.2583	0.1938	NDC80/CENPE/MIS12/CENPC	4
BP	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway	4/2619	13/18670	0.09721	0.2583	0.1938	NTF3/CYFIP2/AGT/CYFIP1	4
BP	GO:0061430	bone trabecula morphogenesis	4/2619	13/18670	0.09721	0.2583	0.1938	SFRP1/SEMA4D/CHAD/SBNO2	4
BP	GO:0061478	response to platelet aggregation inhibitor	4/2619	13/18670	0.09721	0.2583	0.1938	FDX1/EFNA5/ADCY1/ADCY2	4
BP	GO:0072044	collecting duct development	4/2619	13/18670	0.09721	0.2583	0.1938	AKR1B1/NOTCH1/BMP4/AQP2	4
BP	GO:0090594	inflammatory response to wounding	4/2619	13/18670	0.09721	0.2583	0.1938	F2R/HIF1A/TIMP1/CCR2	4
BP	GO:0097152	mesenchymal cell apoptotic process	4/2619	13/18670	0.09721	0.2583	0.1938	SOX9/GDF5/ETV6/HIF1A	4
BP	GO:0098703	calcium ion import across plasma membrane	4/2619	13/18670	0.09721	0.2583	0.1938	PRNP/FAM155A/CALCR/ATP2B4	4
BP	GO:1902285	semaphorin-plexin signaling pathway involved in neuron projection guidance	4/2619	13/18670	0.09721	0.2583	0.1938	SEMA3A/SEMA3F/PLXND1/PLXNA1	4
BP	GO:1902947	regulation of tau-protein kinase activity	4/2619	13/18670	0.09721	0.2583	0.1938	CLU/HGF/IFNG/EGR1	4
BP	GO:2000194	regulation of female gonad development	4/2619	13/18670	0.09721	0.2583	0.1938	NUPR1/INSR/ZFPM2/GDF9	4
BP	GO:0050804	modulation of chemical synaptic transmission	71/2619	436/18670	0.09797	0.2603	0.1952	PTN/LGMN/CDH2/JAK2/TACR2/SNCA/USP46/RIMS3/PREPL/SH3GL1/PRKCB/ABHD6/SYT11/LILRB2/SLC7A11/CD38/FGF14/TUBB2B/EGFR/PRNP/PFN2/BAIAP2/MCTP1/PINK1/CX3CR1/NTRK2/APOE/GSK3B/PCDH17/NTF3/KIT/GPER1/SIPA1L1/F2R/ADRB2/NTRK1/YWHAH/PLK2/RGS4/CHRNA3/AGT/SNCAIP/HCRT/GHSR/ADCY1/CDC20/TYROBP/EPHA4/CA2/USP8/PPP3CA/VAMP2/CACNB2/NRGN/CALB2/AKAP9/TAC1/CACNA1D/CREB1/SYT1/NCDN/CYFIP1/KRAS/SYN1/PTK2B/RAP1B/CCR2/CAMK2B/NAPA/BDNF/STAU1	71
BP	GO:0051168	nuclear export	34/2619	194/18670	0.09821	0.2608	0.1956	HNRNPA2B1/MALT1/NXF3/NUP160/THOC2/BARD1/NUP153/XPO6/DDX39A/THOC1/GSK3B/TPR/NUP50/SEC13/NMD3/RANBP2/NXF1/SRSF4/NUP210/HNRNPA1/RITA1/CAMK1/NUP43/NDC1/SETD2/AKAP13/GTSE1/YTHDC1/TCF7L2/NCBP2/EIF6/NUP98/NUP62/NEMF	34
BP	GO:0008156	negative regulation of DNA replication	9/2619	40/18670	0.09872	0.2611	0.1959	FBXW7/ATR/CHEK2/DONSON/HCRT/BRCA2/SMC1A/TIMELESS/FBXO5	9
BP	GO:0009395	phospholipid catabolic process	9/2619	40/18670	0.09872	0.2611	0.1959	PNPLA6/LIPC/PLCG2/ABHD6/PLA2G15/PRDX6/GDE1/PLA2G4C/APOC1	9
BP	GO:0032008	positive regulation of TOR signaling	9/2619	40/18670	0.09872	0.2611	0.1959	TREM2/RRAGA/SEC13/LAMTOR2/MLST8/RRAGD/GOLPH3/CLEC16A/PIK3CA	9
BP	GO:0035735	intraciliary transport involved in cilium assembly	9/2619	40/18670	0.09872	0.2611	0.1959	IFT46/IFT52/DYNLRB1/PCM1/TNPO1/CLUAP1/IFT140/IFT22/DYNC2LI1	9
BP	GO:0042036	negative regulation of cytokine biosynthetic process	9/2619	40/18670	0.09872	0.2611	0.1959	PTPRC/NMI/ELANE/NFKB1/TIA1/IL6/GHSR/TYROBP/INHBB	9
BP	GO:0050832	defense response to fungus	9/2619	40/18670	0.09872	0.2611	0.1959	FAM3A/ELANE/GNLY/DEFA6/IL17RC/CTSG/DEFA5/S100A12/IL17RA	9
BP	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	9/2619	40/18670	0.09872	0.2611	0.1959	CXCL9/CXCL10/SNCA/SRI/CXCL11/GPER1/F2R/XCL1/CD19	9
BP	GO:0071470	cellular response to osmotic stress	9/2619	40/18670	0.09872	0.2611	0.1959	AKR1B1/DYSF/BAD/SERPINB6/ARHGEF2/RELB/TSPO/MICU1/LETM1	9
BP	GO:0071526	semaphorin-plexin signaling pathway	9/2619	40/18670	0.09872	0.2611	0.1959	SEMA4D/SEMA4A/SEMA3A/SEMA4C/SEMA3F/PLXND1/SEMA3E/PLXNA1/FLNA	9
BP	GO:0044843	cell cycle G1/S phase transition	50/2619	298/18670	0.09978	0.2638	0.1979	CDC7/BTN2A2/FBXW7/RFWD3/CCNA2/CRADD/CHEK2/EZH2/ADAM17/ATM/CDKN2C/EGFR/ORC3/RPA1/BACH1/CDK4/RRM2/CTDSPL/DBF4/RPA3/ORC6/PIM2/MYO16/TAF10/ID4/PLK2/CCNB1/NASP/CCNH/MYC/CRLF3/PML/PPP3CA/ATP2B4/TYMS/GTSE1/CDK1/ID2/TMEM14B/CCND2/NPAT/CDKN1A/WEE1/MNAT1/EP300/CUL2/KANK2/MEPCE/RBL2/FBXO5	50
BP	GO:0031345	negative regulation of cell projection organization	33/2619	188/18670	0.1004	0.2653	0.199	STMN2/GAK/SEMA4D/SEMA4A/SPOCK1/CD38/SEMA3A/FGF13/PRNP/PFN2/ASAP1/ZNF365/APOE/GSK3B/SEMA4C/DGUOK/PMP22/YWHAH/CERS2/PLK2/KLK8/SEMA3F/MAP4K4/TLX2/ITM2C/EPHA4/NR2F1/SEMA3E/PPP3CA/CIB1/NGFR/BCL11A/LRIG2	33
BP	GO:0055024	regulation of cardiac muscle tissue development	19/2619	100/18670	0.1015	0.2666	0.2	NOTCH1/JARID2/RBP4/PIM1/BMP4/FGF20/RGS4/ZFPM2/MAPK11/CTDP1/IGF1/TBX5/CCNB1/RBPJ/PIN1/CREB1/CDK1/ERBB4/FZD7	19
BP	GO:0099177	regulation of trans-synaptic signaling	71/2619	437/18670	0.1015	0.2666	0.2	PTN/LGMN/CDH2/JAK2/TACR2/SNCA/USP46/RIMS3/PREPL/SH3GL1/PRKCB/ABHD6/SYT11/LILRB2/SLC7A11/CD38/FGF14/TUBB2B/EGFR/PRNP/PFN2/BAIAP2/MCTP1/PINK1/CX3CR1/NTRK2/APOE/GSK3B/PCDH17/NTF3/KIT/GPER1/SIPA1L1/F2R/ADRB2/NTRK1/YWHAH/PLK2/RGS4/CHRNA3/AGT/SNCAIP/HCRT/GHSR/ADCY1/CDC20/TYROBP/EPHA4/CA2/USP8/PPP3CA/VAMP2/CACNB2/NRGN/CALB2/AKAP9/TAC1/CACNA1D/CREB1/SYT1/NCDN/CYFIP1/KRAS/SYN1/PTK2B/RAP1B/CCR2/CAMK2B/NAPA/BDNF/STAU1	71
BP	GO:0005979	regulation of glycogen biosynthetic process	7/2619	29/18670	0.1016	0.2666	0.2	ENPP1/GSK3B/INSR/DYRK2/IGF1/PASK/SORBS1	7
BP	GO:0008299	isoprenoid biosynthetic process	7/2619	29/18670	0.1016	0.2666	0.2	PMVK/DHRS9/AKR1C3/DHDDS/ALDH1A3/COQ2/MVK	7
BP	GO:0010962	regulation of glucan biosynthetic process	7/2619	29/18670	0.1016	0.2666	0.2	ENPP1/GSK3B/INSR/DYRK2/IGF1/PASK/SORBS1	7
BP	GO:0018200	peptidyl-glutamic acid modification	7/2619	29/18670	0.1016	0.2666	0.2	VKORC1/AGTPBP1/TTLL4/TTLL1/GGCX/TPGS2/AGBL5	7
BP	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	7/2619	29/18670	0.1016	0.2666	0.2	GOT1/ADAM17/ING2/RNF111/CDKN1C/FERMT1/EP300	7
BP	GO:0031365	N-terminal protein amino acid modification	7/2619	29/18670	0.1016	0.2666	0.2	METAP1/NAA16/NAA50/PPM1B/METAP2/KAT2B/EP300	7
BP	GO:0033014	tetrapyrrole biosynthetic process	7/2619	29/18670	0.1016	0.2666	0.2	FECH/IREB2/UROD/UROS/TSPO/NFE2L1/CPOX	7
BP	GO:0034367	protein-containing complex remodeling	7/2619	29/18670	0.1016	0.2666	0.2	LIPC/APOM/APOE/PLA2G7/APOC1/AGT/LPL	7
BP	GO:0046134	pyrimidine nucleoside biosynthetic process	7/2619	29/18670	0.1016	0.2666	0.2	NME4/TK2/NME7/NME5/NME3/TYMP/CTPS1	7
BP	GO:0060765	regulation of androgen receptor signaling pathway	7/2619	29/18670	0.1016	0.2666	0.2	SFRP1/PHB/BUD31/NCOR1/HDAC1/RNF14/EP300	7
BP	GO:0061099	negative regulation of protein tyrosine kinase activity	7/2619	29/18670	0.1016	0.2666	0.2	PTPRC/PTPN2/CHMP6/FGFR1OP/CBLB/GGNBP2/MVP	7
BP	GO:0070102	interleukin-6-mediated signaling pathway	7/2619	29/18670	0.1016	0.2666	0.2	CEBPA/STAT1/JAK2/JAK1/PTPN2/IL6/IL6R	7
BP	GO:1902624	positive regulation of neutrophil migration	7/2619	29/18670	0.1016	0.2666	0.2	DYSF/THBS4/RAC2/XCL1/CCR7/CXCR2/CXCL8	7
BP	GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus	7/2619	29/18670	0.1016	0.2666	0.2	GOT1/ADAM17/ING2/RNF111/CDKN1C/FERMT1/EP300	7
BP	GO:2000171	negative regulation of dendrite development	7/2619	29/18670	0.1016	0.2666	0.2	ASAP1/GSK3B/YWHAH/PLK2/TLX2/PPP3CA/BCL11A	7
BP	GO:0006221	pyrimidine nucleotide biosynthetic process	10/2619	46/18670	0.1019	0.2671	0.2003	NME4/NME7/AGPAT1/NME5/AGPAT5/NME3/DCTD/CTPS1/TYMS/PRPS1	10
BP	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	10/2619	46/18670	0.1019	0.2671	0.2003	CDH2/ITGAL/ITGA5/SELE/CADM3/TENM3/CD164/CXADR/REG3A/TENM4	10
BP	GO:0015893	drug transport	37/2619	214/18670	0.102	0.2672	0.2004	FOLR1/CD320/SLC18A2/TACR2/SLC7A5/SNCA/PRAF2/SLC25A4/SYT11/SLC7A11/ATP8B1/SLC25A1/PINK1/SLC22A18/FGF20/TMEM30A/SYT17/FOLR2/RGS4/CHRNA3/AGT/ABCC1/MYC/IPCEF1/GHSR/TAF7/SLC11A1/CA2/ARL6IP5/SLC15A2/HBB/GDF9/GAL/LMBRD1/SFXN1/SYT1/SLC1A1	37
BP	GO:0045732	positive regulation of protein catabolic process	37/2619	214/18670	0.102	0.2672	0.2004	TNFAIP3/NUPR1/CEBPA/TREM2/TNFRSF1B/SOX9/FBXW7/CLU/HERPUD1/NDUFA13/CBFA2T3/AREL1/BARD1/EGF/APOE/GSK3B/CHFR/IDE/SEC22B/PSMC2/CD81/IFNG/PLK2/TRIB1/DET1/CSNK1A1/RNF19B/C4BPB/DTL/CSNK1E/EDEM1/PSMD10/RNF14/TRIM32/PTK2B/OAZ3/NEDD4L	37
BP	GO:0000082	G1/S transition of mitotic cell cycle	47/2619	279/18670	0.1025	0.2682	0.2012	CDC7/BTN2A2/RFWD3/CRADD/CHEK2/EZH2/ADAM17/ATM/CDKN2C/EGFR/ORC3/RPA1/BACH1/CDK4/RRM2/CTDSPL/DBF4/RPA3/ORC6/PIM2/MYO16/TAF10/ID4/PLK2/CCNB1/NASP/CCNH/MYC/CRLF3/PML/PPP3CA/TYMS/GTSE1/CDK1/ID2/TMEM14B/CCND2/NPAT/CDKN1A/WEE1/MNAT1/EP300/CUL2/KANK2/MEPCE/RBL2/FBXO5	47
BP	GO:0006805	xenobiotic metabolic process	23/2619	125/18670	0.1025	0.2682	0.2012	GSTA4/PTGS1/EPHX1/BPHL/RORA/EPHX2/AKR7A3/CES2/NQO1/MGST3/GSTM4/AKR7A2/CES3/GSTM5/CRYZ/SULT1A2/GSTM3/FMO3/NAT2/CYB5R3/STAT5A/S100A12/GHR	23
BP	GO:0030326	embryonic limb morphogenesis	23/2619	125/18670	0.1025	0.2682	0.2012	PITX1/HOXA11/NOTCH1/HOXA10/HOXC10/TMEM231/NIPBL/IFT52/BMP4/GDF5/C2CD3/LEF1/MED1/B9D1/OSR2/TBX5/EN1/IFT140/HOXD9/HDAC1/HOXC11/FZD6/TWIST1	23
BP	GO:0035113	embryonic appendage morphogenesis	23/2619	125/18670	0.1025	0.2682	0.2012	PITX1/HOXA11/NOTCH1/HOXA10/HOXC10/TMEM231/NIPBL/IFT52/BMP4/GDF5/C2CD3/LEF1/MED1/B9D1/OSR2/TBX5/EN1/IFT140/HOXD9/HDAC1/HOXC11/FZD6/TWIST1	23
BP	GO:0044728	DNA methylation or demethylation	18/2619	94/18670	0.1027	0.2683	0.2012	DNMT1/FTO/EZH2/ATF7IP/TDG/APOBEC3C/PRMT5/RLF/GATAD2A/MYC/APOBEC3B/ATRX/METTL4/USP9X/HEMK1/PIWIL2/BAZ2A/PIK3CA	18
BP	GO:0060993	kidney morphogenesis	18/2619	94/18670	0.1027	0.2683	0.2012	SIX1/HOXA11/STAT1/SOX9/PGF/CTNNBIP1/PRKX/BMP4/WNT11/KLHL3/GCNT3/LAMA5/AGT/SIX2/MYC/VEGFA/MAGED1/SMO	18
BP	GO:0032088	negative regulation of NF-kappaB transcription factor activity	17/2619	88/18670	0.1037	0.2708	0.2031	ADORA3/TNFAIP3/AIM2/NFKBIA/IRAK3/CD200/DAP/CARD8/CAT/ARRB1/PELI1/TRIM21/CHUK/TRAF3/PSMD10/PRDX2/CYLD	17
BP	GO:0034103	regulation of tissue remodeling	17/2619	88/18670	0.1037	0.2708	0.2031	TNFAIP3/SFRP1/TNFRSF11B/TFRC/THBS4/IL15/CD38/EGFR/LTBP3/TNFRSF11A/ROCK1/S1PR1/AGT/IL6/SUCO/CA2/PPP3CA	17
BP	GO:0009620	response to fungus	11/2619	52/18670	0.1039	0.271	0.2032	MALT1/FAM3A/ELANE/GNLY/DEFA6/IL17RC/CTSG/DEFA5/S100A12/BCL10/IL17RA	11
BP	GO:1900024	regulation of substrate adhesion-dependent cell spreading	11/2619	52/18670	0.1039	0.271	0.2032	GBP1/NEDD9/EFNA5/POSTN/ARHGEF7/MYOC/AP1AR/HAS2/CIB1/FBLN1/FLNA	11
BP	GO:0016925	protein sumoylation	16/2619	82/18670	0.1046	0.2726	0.2045	NUP160/NUP153/TPR/UBE2I/NUP50/ZNF451/TOLLIP/RANBP2/SENP5/EGR1/NUP210/NUP43/NDC1/NUP98/BCL11A/NUP62	16
BP	GO:0030279	negative regulation of ossification	16/2619	82/18670	0.1046	0.2726	0.2045	SFRP1/NOTCH1/SOX9/ENPP1/IGFBP5/SEMA4D/SMAD3/LTBP3/LRP5/RBPJ/HIF1A/ID2/ID3/PTK2B/TWIST1/SRGN	16
BP	GO:0032722	positive regulation of chemokine production	12/2619	58/18670	0.105	0.2734	0.2051	RIPK2/IL4R/ADAM17/POSTN/IFNG/IL6/EGR1/LPL/HIF1A/IL6R/TRIM32/TWIST1	12
BP	GO:0055081	anion homeostasis	12/2619	58/18670	0.105	0.2734	0.2051	ENPP1/SLC12A8/GOT1/SLC7A11/CA12/SLC12A7/APOE/RCN3/CPS1/PRKAA1/XBP1/FABP3	12
BP	GO:1903749	positive regulation of establishment of protein localization to mitochondrion	12/2619	58/18670	0.105	0.2734	0.2051	FBXW7/MICALL2/BAD/PINK1/GZMB/PPP1R13B/YWHAH/TP53BP2/RAC2/ATG13/PRKAA1/UBL5	12
BP	GO:0000422	autophagy of mitochondrion	15/2619	76/18670	0.1052	0.2735	0.2052	FIS1/FBXW7/VPS13C/GABARAPL1/GABARAPL2/PINK1/ATG2B/TSPO/ATG13/OPTN/HIF1A/CTTN/ATG12/GABARAP/CLEC16A	15
BP	GO:0045454	cell redox homeostasis	15/2619	76/18670	0.1052	0.2735	0.2052	GLRX5/PRDX6/SCO2/GPX1/KRIT1/DLD/NOS3/RAC2/SLC11A1/TXN2/PRDX2/ERP44/TXNRD2/DDIT3/NCF1	15
BP	GO:0061726	mitochondrion disassembly	15/2619	76/18670	0.1052	0.2735	0.2052	FIS1/FBXW7/VPS13C/GABARAPL1/GABARAPL2/PINK1/ATG2B/TSPO/ATG13/OPTN/HIF1A/CTTN/ATG12/GABARAP/CLEC16A	15
BP	GO:1902653	secondary alcohol biosynthetic process	15/2619	76/18670	0.1052	0.2735	0.2052	LBR/PMVK/ERLIN2/APOE/SC5D/MBTPS1/DHCR24/DHCR7/KPNB1/SOD1/PRKAA1/CYB5R3/ACAA2/NFYC/MVK	15
BP	GO:0002228	natural killer cell mediated immunity	13/2619	64/18670	0.1055	0.2739	0.2054	RASGRP1/HLA-F/HLA-G/MICB/RAB27A/SLAMF7/HLA-E/GZMB/CD96/CRTAM/VAMP7/ULBP2/CEBPG	13
BP	GO:0035773	insulin secretion involved in cellular response to glucose stimulus	13/2619	64/18670	0.1055	0.2739	0.2054	SRI/MPC2/BAD/EFNA5/ARRB1/OXCT1/PTPRN2/LRP5/MAP4K4/ANO1/HIF1A/RAF1/RAB11B	13
BP	GO:0061572	actin filament bundle organization	28/2619	157/18670	0.1056	0.2739	0.2054	SFRP1/LCP1/SMAD3/PFN2/BAIAP2/NEDD9/CORO2B/LIMCH1/RHOF/WNT11/ROCK1/BBS4/PTGER4/ARRB1/S1PR1/PPM1E/RND2/CLASP1/MYOC/ALMS1/NF2/TAC1/ITGB5/LIMA1/ACTN1/FLNA/PTK2B/SORBS1	28
BP	GO:0001756	somitogenesis	14/2619	70/18670	0.1056	0.2739	0.2054	SFRP1/NOTCH1/SMAD3/FOXC1/MEOX1/NLE1/ATM/LEF1/FOXF1/POFUT1/RBPJ/TMED2/ABI1/EP300	14
BP	GO:0050766	positive regulation of phagocytosis	14/2619	70/18670	0.1056	0.2739	0.2054	IL15RA/TREM2/IL15/IL2RG/RAB27A/PTPRC/MERTK/LMAN2/PPARG/IFNG/IL2RB/SLC11A1/SOD1/MBL2	14
BP	GO:0046620	regulation of organ growth	21/2619	113/18670	0.106	0.275	0.2062	NOTCH1/JARID2/WWC3/DUSP6/FOXC1/RBP4/PIM1/FGF20/RGS4/ZFPM2/MAPK11/CTDP1/IGF1/TBX5/CCNB1/RBPJ/PIN1/SOD1/CDK1/ERBB4/SMO	21
BP	GO:0001881	receptor recycling	8/2619	35/18670	0.1076	0.2784	0.2088	SNCA/EHD3/VAMP3/TBC1D16/TRAT1/AP1AR/OPTN/RAB11B	8
BP	GO:0010259	multicellular organism aging	8/2619	35/18670	0.1076	0.2784	0.2088	ERCC1/ATM/IDE/CRYAB/COMP/WRN/NDUFS6/TH	8
BP	GO:0046131	pyrimidine ribonucleoside metabolic process	8/2619	35/18670	0.1076	0.2784	0.2088	NME4/NME7/ENTPD4/NME5/APOBEC3C/NME3/APOBEC3B/CTPS1	8
BP	GO:0060251	regulation of glial cell proliferation	8/2619	35/18670	0.1076	0.2784	0.2088	PTN/NOTCH1/PRKCH/CERS2/PRKCI/TSPO/IL6/CREB1	8
BP	GO:0110111	negative regulation of animal organ morphogenesis	8/2619	35/18670	0.1076	0.2784	0.2088	NOTCH1/DIO3/STAT1/TNFRSF11B/FBXW7/FOXC1/BMP4/CHAD	8
BP	GO:0038093	Fc receptor signaling pathway	41/2619	241/18670	0.1076	0.2784	0.2088	MS4A2/MAPK3/ARPC1A/PLCG2/SKP1/MALT1/FCER1A/PTPRC/SOS1/PSMB9/ITK/BAIAP2/ACTR3/KIT/IGLV1-44/PSMC2/CYFIP2/FGR/NFKB1/PSMB6/WIPF1/CHUK/PIK3CB/PSMC3/CD247/PSMD8/PRKCQ/PSMB5/PPP3CA/IGLC1/LAT/ABI1/PSMD10/IKBKG/PAK2/BCL10/CYFIP1/CD3G/LCP2/ACTR2/PIK3CA	41
BP	GO:0051341	regulation of oxidoreductase activity	20/2619	107/18670	0.1077	0.2785	0.2089	SLAMF8/GCH1/SNCA/DDAH1/EGFR/APOE/HTR2B/GZMA/NFKB1/DDAH2/IFNG/AGT/NOS3/S100A1/NOD2/HIF1A/ATP2B4/NOD1/KRAS/PTK2B	20
BP	GO:0051236	establishment of RNA localization	34/2619	196/18670	0.1092	0.2807	0.2106	CETN2/HNRNPA2B1/ATR/NXF3/NUP160/RFTN1/IGF2BP3/ATM/THOC2/NUP153/DDX39A/THOC1/TPR/NUP50/SEC13/NMD3/RANBP2/NXF1/KIF5C/SNUPN/SRSF4/NUP210/HNRNPA1/SFPQ/NUP43/NDC1/SETD2/YTHDC1/NCBP2/EIF6/MVP/MRPL18/NUP98/NUP62	34
BP	GO:0001919	regulation of receptor recycling	6/2619	24/18670	0.1093	0.2807	0.2106	SNCA/VAMP3/TBC1D16/TRAT1/AP1AR/OPTN	6
BP	GO:0007097	nuclear migration	6/2619	24/18670	0.1093	0.2807	0.2106	CLMN/SYNE2/PCM1/DYNC1H1/MYH10/TRIM58	6
BP	GO:0009218	pyrimidine ribonucleotide metabolic process	6/2619	24/18670	0.1093	0.2807	0.2106	NME4/NME7/ENTPD4/NME5/NME3/CTPS1	6
BP	GO:0031579	membrane raft organization	6/2619	24/18670	0.1093	0.2807	0.2106	PTPRC/RFTN1/EMP2/CD2/FA2H/NPC1	6
BP	GO:0032897	negative regulation of viral transcription	6/2619	24/18670	0.1093	0.2807	0.2106	CCL5/TRIM21/HDAC1/TARDBP/TRIM32/HMGA2	6
BP	GO:0033119	negative regulation of RNA splicing	6/2619	24/18670	0.1093	0.2807	0.2106	HNRNPA2B1/HNRNPK/PTBP3/SFSWAP/SRSF4/PTBP2	6
BP	GO:0034162	toll-like receptor 9 signaling pathway	6/2619	24/18670	0.1093	0.2807	0.2106	TNIP2/IRAK4/HMGB1/GRAMD4/MYD88/TLR8	6
BP	GO:0042832	defense response to protozoan	6/2619	24/18670	0.1093	0.2807	0.2106	GBP2/IL4R/CD40/SLC11A1/BATF/TSPAN32	6
BP	GO:0045606	positive regulation of epidermal cell differentiation	6/2619	24/18670	0.1093	0.2807	0.2106	NOTCH1/FOXC1/NCOA3/PRKCH/BMP4/MED1	6
BP	GO:0046135	pyrimidine nucleoside catabolic process	6/2619	24/18670	0.1093	0.2807	0.2106	ENTPD4/APOBEC3C/DPYS/TYMP/APOBEC3B/NT5E	6
BP	GO:0046639	negative regulation of alpha-beta T cell differentiation	6/2619	24/18670	0.1093	0.2807	0.2106	IL4R/RUNX3/SOCS1/RC3H2/TNFSF4/HMGB1	6
BP	GO:0099563	modification of synaptic structure	6/2619	24/18670	0.1093	0.2807	0.2106	PFN2/BAIAP2/EPHA4/CYFIP1/MYH10/STAU1	6
BP	GO:1902410	mitotic cytokinetic process	6/2619	24/18670	0.1093	0.2807	0.2106	CEP55/CHMP6/CHMP2A/CHMP1B/KIF20A/NUP62	6
BP	GO:1903421	regulation of synaptic vesicle recycling	6/2619	24/18670	0.1093	0.2807	0.2106	SNCA/SH3GL1/SYT11/FGF14/ROCK1/CYFIP1	6
BP	GO:0032649	regulation of interferon-gamma production	19/2619	101/18670	0.1093	0.2808	0.2106	RASGRP1/IL27RA/RIPK2/PRNP/CD96/PTPN22/CD3E/TXK/AXL/XCL1/SLC11A1/TNFSF4/HMGB1/CCR7/CD2/IL6R/CEBPG/TLR8/CCR2	19
BP	GO:0045667	regulation of osteoblast differentiation	23/2619	126/18670	0.1096	0.2813	0.211	SFRP1/NOTCH1/CEBPA/NELL1/IGFBP5/SEMA4D/SMAD3/ATRAID/HGF/CTNNBIP1/BMP4/TCIRG1/LRP5/IGF1/IL6/SUCO/IL6R/ID2/ID3/CEBPB/GDPD2/TWIST1/FBXO5	23
BP	GO:0071901	negative regulation of protein serine/threonine kinase activity	26/2619	145/18670	0.11	0.2824	0.2118	TNFAIP3/DUSP5/SFRP1/CEBPA/IRAK3/PRKAR2A/DUSP6/UCHL1/CDKN2C/APOE/CHORDC1/LAX1/BMP4/DNAJA1/PTPN22/HSPB1/RGS4/LRP5/RASIP1/CDKN1C/DUSP2/CIB1/KAT2B/CDKN1A/SH2B3/NUP62	26
BP	GO:0001701	in utero embryonic development	61/2619	373/18670	0.1106	0.2836	0.2127	NOTCH1/CEBPA/TCTN1/AR/TMEM231/PEMT/CHD8/ANGPT1/NBN/SMAD3/TMEM100/FOXC1/NLE1/PTH1R/EGFR/ADA/MDFI/RXRA/C2CD3/LEF1/MED1/B9D1/NDUFA2/TIE1/FOXF1/GINS1/WDTC1/CCNB2/MAFF/ZFPM2/IGF1/NOS3/DAD1/CCNB1/NASP/PSMC3/CDKN1C/BRCA2/PSPH/RBPJ/PDGFB/PRDM1/VEGFA/FUT8/ADAMTS3/TMED2/PLCD1/JAG2/HIF1A/ERCC2/SETD2/SSR2/BTF3/BPTF/GGNBP2/NPAT/CEBPB/SMO/MYH10/TWIST1/RTCB	61
BP	GO:0110020	regulation of actomyosin structure organization	18/2619	95/18670	0.1109	0.2843	0.2132	SFRP1/ECT2/SMAD3/PFN2/CORO2B/LIMCH1/WNT11/ROCK1/BBS4/PTGER4/S1PR1/PPM1E/CLASP1/MYOC/ALMS1/NF2/TAC1/AKAP13	18
BP	GO:0035136	forelimb morphogenesis	9/2619	41/18670	0.1115	0.2856	0.2142	HOXA11/NIPBL/GDF5/OSR2/TBX5/EN1/ATRX/HOXD9/TWIST1	9
BP	GO:0042572	retinol metabolic process	9/2619	41/18670	0.1115	0.2856	0.2142	AKR1B1/PNPLA4/AKR1B10/ALDH1A1/DHRS3/DHRS9/RBP4/AKR1C3/ALDH1A3	9
BP	GO:0043403	skeletal muscle tissue regeneration	9/2619	41/18670	0.1115	0.2856	0.2142	SGCA/DYSF/CFLAR/EZH2/GPX1/CD81/IGF1/PPP3CA/FZD7	9
BP	GO:1903053	regulation of extracellular matrix organization	9/2619	41/18670	0.1115	0.2856	0.2142	NOTCH1/TNFRSF1B/SOX9/SMAD3/CFLAR/AGT/IL6/CLASP1/HAS2	9
BP	GO:0032465	regulation of cytokinesis	17/2619	89/18670	0.1123	0.2872	0.2154	CDC25B/CETN2/ECT2/UVRAG/RACGAP1/BBS4/CDC14A/PRC1/PLK2/BRCA2/AURKB/PIN1/SSTR5/SPAST/SETD2/KIF20A/NUP62	17
BP	GO:0061053	somite development	17/2619	89/18670	0.1123	0.2872	0.2154	SIX1/SFRP1/NOTCH1/SMAD3/FOXC1/MEOX1/NLE1/ATM/WNT11/LEF1/FOXF1/POFUT1/RBPJ/TMED2/ABI1/EP300/SMO	17
BP	GO:0010634	positive regulation of epithelial cell migration	30/2619	171/18670	0.1133	0.2898	0.2173	LGMN/SOX9/PRKD2/ANGPT1/ADAM17/AAMP/BMP4/CD40/HSPB1/IFNG/PLK2/AGT/NOS3/FGF18/KDR/MAP4K4/HBEGF/CLASP1/PDGFB/VEGFA/P2RX4/HMGB1/MAP3K3/HIF1A/HAS2/TAC1/CIB1/STAT5A/MAPRE2/PTK2B	30
BP	GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	10/2619	47/18670	0.114	0.2908	0.2181	RIPK2/MALT1/IL4R/RUNX3/CD83/SOCS1/RC3H2/IFNG/TNFSF4/HMGB1	10
BP	GO:0060986	endocrine hormone secretion	10/2619	47/18670	0.114	0.2908	0.2181	TACR2/RAB11FIP1/AGT/CRHBP/TMF1/TAC1/GDF9/GAL/CRY1/INHBB	10
BP	GO:0061383	trabecula morphogenesis	10/2619	47/18670	0.114	0.2908	0.2181	SFRP1/NOTCH1/SEMA4D/SOS1/RBP4/MED1/CHAD/S1PR1/RBPJ/SBNO2	10
BP	GO:0070231	T cell apoptotic process	10/2619	47/18670	0.114	0.2908	0.2181	CCL5/IL7R/IDO1/ADA/BMP4/CD27/PRKCQ/HIF1A/LGALS3/BCL10	10
BP	GO:1900744	regulation of p38MAPK cascade	10/2619	47/18670	0.114	0.2908	0.2181	SPHK1/MAP3K5/HGF/PTPN22/MFHAS1/VEGFA/MAP3K3/CYLD/PHLPP1/NCF1	10
BP	GO:0016202	regulation of striated muscle tissue development	27/2619	152/18670	0.1144	0.2916	0.2187	SIX1/NOTCH1/JARID2/SMAD3/RBP4/PIM1/BMP4/FGF20/LEF1/RGS4/ZFPM2/MAPK11/CTDP1/IGF1/TBX5/CCNB1/RBPJ/PIN1/PRKAA1/CREB1/CDK1/LUC7L/ERBB4/FZD7/CENPF/TWIST1/NR1D2	27
BP	GO:0030902	hindbrain development	27/2619	152/18670	0.1144	0.2916	0.2187	PTN/RORA/FOXC1/SDF4/EZH2/B4GALT2/AGTPBP1/EGF/ZNF365/SEMA4C/HERC1/LEF1/NAGLU/MYO16/CD3E/WLS/EN1/PTBP2/UQCRQ/PSMG1/CEP290/FLNA/HNRNPD/SEZ6L/SMO/HSPA5/MYH10	27
BP	GO:0071333	cellular response to glucose stimulus	24/2619	133/18670	0.1146	0.2918	0.2189	FIS1/SRI/MPC2/BAD/EFNA5/CMA1/GPER1/ARRB1/OXCT1/POLG/PTPRN2/LRP5/MAP4K4/PCK2/ANO1/PPP3CA/HIF1A/PRKAA1/RAF1/RAB11B/XBP1/SERPINF1/TH/PIK3CA	24
BP	GO:0048332	mesoderm morphogenesis	15/2619	77/18670	0.1146	0.2918	0.2189	HOXA11/EYA2/SMAD3/FOXC1/EXT2/BMP4/WNT11/LEF1/FOXF1/WLS/SIX2/TLX2/SETD2/NF2/HMGA2	15
BP	GO:0048678	response to axon injury	15/2619	77/18670	0.1146	0.2918	0.2189	PTN/FOLR1/JAK2/PTPRF/NTRK1/CERS2/KLK8/TSPO/TYROBP/EPHA4/TXN2/P2RX4/SOD1/CDK1/LRIG2	15
BP	GO:0009749	response to glucose	34/2619	197/18670	0.115	0.2927	0.2196	FIS1/SRI/APOM/MPC2/BAD/ANGPT2/EFNA5/CMA1/RMI1/GPER1/ARRB1/OXCT1/POLG/PTPRN2/LRP5/MAP4K4/EGR1/PCK2/TXN2/ANO1/PPP3CA/VAMP2/LPL/HIF1A/PRKAA1/RAF1/RAB11B/TCF7L2/ENSA/XBP1/PTK2B/SERPINF1/TH/PIK3CA	34
BP	GO:0010043	response to zinc ion	11/2619	53/18670	0.1153	0.293	0.2197	HAAO/KCNK3/GGH/KRT14/ASS1/TSPO/CPS1/CA2/P2RX4/CREB1/TH	11
BP	GO:0031122	cytoplasmic microtubule organization	11/2619	53/18670	0.1153	0.293	0.2197	TUBG2/CCDC88C/PCM1/CLASP1/TUBGCP5/DYNC1H1/KPNB1/SPAST/CIB1/HOOK2/TUBGCP2	11
BP	GO:0038066	p38MAPK cascade	11/2619	53/18670	0.1153	0.293	0.2197	SPHK1/MAP3K5/HGF/PTPN22/MFHAS1/VEGFA/MAPKAPK2/MAP3K3/CYLD/PHLPP1/NCF1	11
BP	GO:0042073	intraciliary transport	11/2619	53/18670	0.1153	0.293	0.2197	IFT46/ARL3/RPGR/IFT52/DYNLRB1/PCM1/TNPO1/CLUAP1/IFT140/IFT22/DYNC2LI1	11
BP	GO:1905517	macrophage migration	11/2619	53/18670	0.1153	0.293	0.2197	SLAMF8/TREM2/CD200/CCL5/MAPK3/CX3CR1/CD81/P2RX4/LGALS3/PTK2B/CCR2	11
BP	GO:0006940	regulation of smooth muscle contraction	13/2619	65/18670	0.1159	0.293	0.2197	SPHK1/TACR2/ADA/KIT/GPER1/F2R/ADRB2/CHRNA3/GHSR/PLCE1/SOD1/CTTN/ATP2B1	13
BP	GO:0032729	positive regulation of interferon-gamma production	13/2619	65/18670	0.1159	0.293	0.2197	RASGRP1/IL27RA/RIPK2/PTPN22/CD3E/TXK/SLC11A1/TNFSF4/CD2/IL6R/CEBPG/TLR8/CCR2	13
BP	GO:0045739	positive regulation of DNA repair	13/2619	65/18670	0.1159	0.293	0.2197	EYA2/PARP3/SMCHD1/EGFR/DDX11/MMS19/SETMAR/FOXM1/HMGB1/TIMELESS/BABAM1/CEBPG/ACTR2	13
BP	GO:0071806	protein transmembrane transport	13/2619	65/18670	0.1159	0.293	0.2197	PEX10/CLU/NDUFA13/RTN2/TIMM10/PEX7/PEX2/SEC61A2/PEX12/PEX14/MCL1/SRP54/HSPA5	13
BP	GO:0070527	platelet aggregation	12/2619	59/18670	0.1159	0.293	0.2197	SLC7A11/METAP1/FIBP/HSPB1/PIK3CB/COMP/PRKCQ/HBB/TYRO3/SH2B3/FLNA/TSPAN32	12
BP	GO:0050768	negative regulation of neurogenesis	49/2619	295/18670	0.116	0.293	0.2197	BRINP1/PTN/NOTCH1/DIO3/SOX9/STMN2/GAK/SEMA4D/ASPM/SEMA4A/SPOCK1/CD38/SEMA3A/FGF13/ASAP1/ZNF365/APOE/GSK3B/SEMA4C/ARHGEF2/DGUOK/MED1/PMP22/YWHAH/ID4/CERS2/PLK2/KLK8/PCM1/SEMA3F/TSPO/MAP4K4/IL6/TLX2/ITM2C/EPHA4/NR2F1/SEMA3E/PPP3CA/CIB1/SIX3/NGFR/OLIG2/ID2/ID3/ERBB4/COL3A1/BCL11A/LRIG2	49
BP	GO:0002726	positive regulation of T cell cytokine production	5/2619	19/18670	0.1164	0.293	0.2197	MALT1/CD81/IL6/XCL1/TNFSF4	5
BP	GO:0032700	negative regulation of interleukin-17 production	5/2619	19/18670	0.1164	0.293	0.2197	IL27RA/PRNP/TUSC2/IFNG/TNFSF4	5
BP	GO:0034063	stress granule assembly	5/2619	19/18670	0.1164	0.293	0.2197	CIRBP/PUM2/DYNC1H1/PRKAA1/STYXL1	5
BP	GO:0034312	diol biosynthetic process	5/2619	19/18670	0.1164	0.293	0.2197	GCH1/SPHK1/QDPR/PCBD1/ASAH1	5
BP	GO:0034755	iron ion transmembrane transport	5/2619	19/18670	0.1164	0.293	0.2197	HFE/IFNG/SLC11A1/SLC39A14/MCOLN1	5
BP	GO:0035493	SNARE complex assembly	5/2619	19/18670	0.1164	0.293	0.2197	SNCA/UVRAG/VAMP3/VPS16/VAMP7	5
BP	GO:0042789	mRNA transcription by RNA polymerase II	5/2619	19/18670	0.1164	0.293	0.2197	MED1/HIF1A/FLNA/ATF4/DDIT3	5
BP	GO:0045076	regulation of interleukin-2 biosynthetic process	5/2619	19/18670	0.1164	0.293	0.2197	PTPRC/CD28/CD3E/GLMN/PRKCQ	5
BP	GO:0051546	keratinocyte migration	5/2619	19/18670	0.1164	0.293	0.2197	MAP4K4/HBEGF/FERMT1/HAS2/MAPRE2	5
BP	GO:0060149	negative regulation of posttranscriptional gene silencing	5/2619	19/18670	0.1164	0.293	0.2197	ADAR/PPARG/DND1/PPP3CA/NCOR1	5
BP	GO:0060219	camera-type eye photoreceptor cell differentiation	5/2619	19/18670	0.1164	0.293	0.2197	PTN/DIO3/SOX9/ROM1/DSCAM	5
BP	GO:0060231	mesenchymal to epithelial transition	5/2619	19/18670	0.1164	0.293	0.2197	STAT1/BMP4/SIX2/FZD7/SMO	5
BP	GO:0060967	negative regulation of gene silencing by RNA	5/2619	19/18670	0.1164	0.293	0.2197	ADAR/PPARG/DND1/PPP3CA/NCOR1	5
BP	GO:0060973	cell migration involved in heart development	5/2619	19/18670	0.1164	0.293	0.2197	NOTCH1/FOLR1/BMP4/TBX5/TWIST1	5
BP	GO:0072074	kidney mesenchyme development	5/2619	19/18670	0.1164	0.293	0.2197	SIX1/STAT1/BMP4/SIX2/MYC	5
BP	GO:0072087	renal vesicle development	5/2619	19/18670	0.1164	0.293	0.2197	STAT1/SOX9/BMP4/SIX2/SMO	5
BP	GO:2000010	positive regulation of protein localization to cell surface	5/2619	19/18670	0.1164	0.293	0.2197	CD247/TYROBP/RANGRF/ERBB4/LRIG2	5
BP	GO:2000831	regulation of steroid hormone secretion	5/2619	19/18670	0.1164	0.293	0.2197	AGT/TAC1/GDF9/GAL/CRY1	5
BP	GO:0032368	regulation of lipid transport	23/2619	127/18670	0.1169	0.2937	0.2203	NFKBIA/EGF/TNFRSF11A/APOE/HNRNPK/PPARG/NFKB1/APOC1/AGT/TSPO/NR1H2/SCP2/ABCA2/ATP8A1/P2RX4/PLA2R1/NCOR1/TMF1/TAC1/GDF9/GAL/CRY1/FABP3	23
BP	GO:0071426	ribonucleoprotein complex export from nucleus	23/2619	127/18670	0.1169	0.2937	0.2203	HNRNPA2B1/NXF3/NUP160/THOC2/NUP153/DDX39A/THOC1/TPR/NUP50/SEC13/NMD3/RANBP2/NXF1/SRSF4/NUP210/NUP43/NDC1/SETD2/YTHDC1/NCBP2/EIF6/NUP98/NUP62	23
BP	GO:0090090	negative regulation of canonical Wnt signaling pathway	31/2619	178/18670	0.117	0.2937	0.2203	SFRP1/NOTCH1/WNT5B/CDH2/SOX9/IGFBP2/CHD8/PSMB9/APOE/GSK3B/IGFBP4/WNT11/PSMC2/PSMB6/PSMC3/EGR1/CSNK1A1/DKK4/PSMD8/FERMT1/PSMB5/RUVBL2/PFDN5/PSMD10/TLE3/HDAC1/CYLD/TCF7L2/TLE2/FZD6/DDIT3	31
BP	GO:0000305	response to oxygen radical	7/2619	30/18670	0.1173	0.2937	0.2203	GCH1/FBLN5/NQO1/NOS3/SOD1/PRDX2/TXNRD2	7
BP	GO:0010743	regulation of macrophage derived foam cell differentiation	7/2619	30/18670	0.1173	0.2937	0.2203	NFKBIA/PRKCH/PPARG/NFKB1/AGT/NR1H2/LPL	7
BP	GO:0032728	positive regulation of interferon-beta production	7/2619	30/18670	0.1173	0.2937	0.2203	IRF1/RIPK2/TBK1/POLR3C/IRF3/RIOK3/TLR8	7
BP	GO:0038111	interleukin-7-mediated signaling pathway	7/2619	30/18670	0.1173	0.2937	0.2203	IL2RG/IL7R/SOCS1/BRWD1/JAK1/STAT5A/CISH	7
BP	GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	7/2619	30/18670	0.1173	0.2937	0.2203	RIPK2/MALT1/IL4R/CD83/SOCS1/IFNG/TNFSF4	7
BP	GO:0048147	negative regulation of fibroblast proliferation	7/2619	30/18670	0.1173	0.2937	0.2203	SFRP1/NUPR1/PPARG/PEX2/B4GALT7/MYC/TRIM32	7
BP	GO:0050690	regulation of defense response to virus by virus	7/2619	30/18670	0.1173	0.2937	0.2203	AP1B1/AP2M1/CD28/LCK/CD247/AP1S1/PAK2	7
BP	GO:0061082	myeloid leukocyte cytokine production	7/2619	30/18670	0.1173	0.2937	0.2203	IRAK3/HLA-G/KIT/CUEDC2/DDX1/DDX21/BCL10	7
BP	GO:0097421	liver regeneration	7/2619	30/18670	0.1173	0.2937	0.2203	EZH2/EGFR/PRMT5/HFE/CSNK2B/TYMS/CEBPB	7
BP	GO:0090596	sensory organ morphogenesis	43/2619	256/18670	0.1177	0.2947	0.221	ZIC1/SIX1/EFEMP1/PTN/DIO3/SOX9/MAPK3/NIPBL/RBP4/AGTPBP1/NTRK2/BMP4/FAT1/FZD3/BBS4/NAGLU/ROM1/PRKRA/OSR2/ARID1A/LRP5/PRKCI/SIX2/PRDM1/VEGFA/ALDH1A3/TSKU/TENM3/RS1/IRX5/SOD1/PHACTR4/HIF1A/HDAC1/SIX3/CEP290/RING1/FZD6/DSCAM/NRL/TH/TWIST1/FZD2	43
BP	GO:0060348	bone development	37/2619	217/18670	0.1183	0.296	0.222	HOXA11/VKORC1/SCARA3/SOX9/SEMA4D/FBXW7/DHRS3/PTPRC/FOXC1/LTBP3/STC1/KIT/BMP4/NAB1/MED1/CHAD/PEX7/PTGER4/OSR2/NPR2/LRP5/IGF1/COMP/FGF18/MMP13/MYOC/TYROBP/COL6A3/ABI1/MBL2/HAS2/PPIB/AKAP13/EP300/SH2B3/TRIM45/TWIST1	37
BP	GO:0001704	formation of primary germ layer	22/2619	121/18670	0.1192	0.2982	0.2237	HOXA11/EYA2/SMAD3/FOXC1/ITGA5/EXT2/BMP4/WNT11/LEF1/ARID1A/FOXF1/WLS/SIX2/HSBP1/TLX2/SETD2/NF2/ITGB5/ETS2/COL4A2/FZD7/HMGA2	22
BP	GO:0021543	pallium development	30/2619	172/18670	0.1197	0.2992	0.2244	CDH2/NDE1/ASPM/BCL2A1/SEMA3A/EZH2/SYNE2/FGF13/BAD/SLC38A2/EGFR/NTRK2/GSK3B/LEF1/GNG12/BBS4/ID4/TACC2/HIF1A/HDAC1/NF2/UQCRQ/ATP2B4/TACC3/TMEM14B/COL3A1/FLNA/SMO/EMX2/TH	30
BP	GO:0042475	odontogenesis of dentin-containing tooth	17/2619	90/18670	0.1213	0.3009	0.2257	TNFRSF11B/FOXC1/BSG/SERPINE1/BCL11B/HTRA1/BMP4/LEF1/LAMA5/TCIRG1/CA2/JAG2/HDAC1/MMP20/NF2/ATF2/SMO	17
BP	GO:0002523	leukocyte migration involved in inflammatory response	4/2619	14/18670	0.1216	0.3009	0.2257	SLAMF8/PTN/SELE/ELANE	4
BP	GO:0006268	DNA unwinding involved in DNA replication	4/2619	14/18670	0.1216	0.3009	0.2257	RECQL/RPA1/WRN/HMGA1	4
BP	GO:0006878	cellular copper ion homeostasis	4/2619	14/18670	0.1216	0.3009	0.2257	PRNP/SCO2/SLC31A2/PRND	4
BP	GO:0006896	Golgi to vacuole transport	4/2619	14/18670	0.1216	0.3009	0.2257	GAK/EHD3/VTI1B/AP4M1	4
BP	GO:0006999	nuclear pore organization	4/2619	14/18670	0.1216	0.3009	0.2257	NUP153/TPR/NDC1/NUP98	4
BP	GO:0007100	mitotic centrosome separation	4/2619	14/18670	0.1216	0.3009	0.2257	NDE1/CHEK1/KIF11/NUP62	4
BP	GO:0030213	hyaluronan biosynthetic process	4/2619	14/18670	0.1216	0.3009	0.2257	EGF/NFKB1/PDGFB/HAS2	4
BP	GO:0032688	negative regulation of interferon-beta production	4/2619	14/18670	0.1216	0.3009	0.2257	REL/NMI/RELB/PPM1B	4
BP	GO:0035112	genitalia morphogenesis	4/2619	14/18670	0.1216	0.3009	0.2257	AR/NIPBL/TCF7/RBP4	4
BP	GO:0045605	negative regulation of epidermal cell differentiation	4/2619	14/18670	0.1216	0.3009	0.2257	NOTCH1/EZH2/HOXA7/REG3A	4
BP	GO:0046033	AMP metabolic process	4/2619	14/18670	0.1216	0.3009	0.2257	ADK/AK1/NT5E/AMPD3	4
BP	GO:0046037	GMP metabolic process	4/2619	14/18670	0.1216	0.3009	0.2257	IMPDH2/GUK1/MPP1/TJP2	4
BP	GO:0050667	homocysteine metabolic process	4/2619	14/18670	0.1216	0.3009	0.2257	CBS/COMT/MPST/CPS1	4
BP	GO:0051547	regulation of keratinocyte migration	4/2619	14/18670	0.1216	0.3009	0.2257	MAP4K4/HBEGF/HAS2/MAPRE2	4
BP	GO:0051852	disruption by host of symbiont cells	4/2619	14/18670	0.1216	0.3009	0.2257	ELANE/TUSC2/MBL2/CTSG	4
BP	GO:0071941	nitrogen cycle metabolic process	4/2619	14/18670	0.1216	0.3009	0.2257	CEBPA/SUOX/ASS1/CPS1	4
BP	GO:0072425	signal transduction involved in G2 DNA damage checkpoint	4/2619	14/18670	0.1216	0.3009	0.2257	CHEK1/ATM/DTL/BABAM1	4
BP	GO:0072498	embryonic skeletal joint development	4/2619	14/18670	0.1216	0.3009	0.2257	HOXA11/BMP4/OSR2/HOXC11	4
BP	GO:0090069	regulation of ribosome biogenesis	4/2619	14/18670	0.1216	0.3009	0.2257	HEATR1/TRMT112/WDR43/DIMT1	4
BP	GO:0090231	regulation of spindle checkpoint	4/2619	14/18670	0.1216	0.3009	0.2257	TPR/LCMT1/NDC80/CCNB1	4
BP	GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint	4/2619	14/18670	0.1216	0.3009	0.2257	TPR/LCMT1/NDC80/CCNB1	4
BP	GO:0099171	presynaptic modulation of chemical synaptic transmission	4/2619	14/18670	0.1216	0.3009	0.2257	PRKCB/CACNB2/CACNA1D/SYT1	4
BP	GO:1900121	negative regulation of receptor binding	4/2619	14/18670	0.1216	0.3009	0.2257	PTPRF/HFE/LEF1/RUVBL2	4
BP	GO:1901626	regulation of postsynaptic membrane organization	4/2619	14/18670	0.1216	0.3009	0.2257	PTN/CDH2/SLC7A11/APOE	4
BP	GO:1903504	regulation of mitotic spindle checkpoint	4/2619	14/18670	0.1216	0.3009	0.2257	TPR/LCMT1/NDC80/CCNB1	4
BP	GO:1904263	positive regulation of TORC1 signaling	4/2619	14/18670	0.1216	0.3009	0.2257	RRAGA/SEC13/RRAGD/CLEC16A	4
BP	GO:0006766	vitamin metabolic process	24/2619	134/18670	0.1219	0.301	0.2258	THTPA/SLC2A3/VKORC1/FOLR1/LGMN/CD320/MTHFD2/ENPP1/HAAO/PNPO/PCCB/CYP11A1/RXRA/PC/NFKB1/FOLR2/IFNG/ABCC1/AKR1C3/CYP4F11/CYB5R3/LMBRD1/VNN1/CBR1	24
BP	GO:0002755	MyD88-dependent toll-like receptor signaling pathway	8/2619	36/18670	0.1223	0.301	0.2258	IRAK3/IRF1/TNIP1/TLR5/IRAK4/UBB/MYD88/TLR8	8
BP	GO:0006699	bile acid biosynthetic process	8/2619	36/18670	0.1223	0.301	0.2258	CH25H/OSBPL3/ACOX2/SLC27A5/CYP7B1/SCP2/ACOT8/AKR1C4	8
BP	GO:0009112	nucleobase metabolic process	8/2619	36/18670	0.1223	0.301	0.2258	ADA/DPYS/TYMP/CPS1/CTPS1/TYMS/ALDH6A1/PRPS1	8
BP	GO:0030224	monocyte differentiation	8/2619	36/18670	0.1223	0.301	0.2258	CTNNBIP1/BMP4/MED1/PPARG/MYC/VEGFA/IFI16/HOXA7	8
BP	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	8/2619	36/18670	0.1223	0.301	0.2258	PRKD2/PRKCB/ITGA5/TNMD/GRB10/FGF18/VEGFA/HIF1A	8
BP	GO:0035137	hindlimb morphogenesis	8/2619	36/18670	0.1223	0.301	0.2258	PITX1/NOTCH1/BMP4/GDF5/MED1/OSR2/HOXD9/TWIST1	8
BP	GO:0045740	positive regulation of DNA replication	8/2619	36/18670	0.1223	0.301	0.2258	CDC7/DNA2/EGFR/DBF4/EREG/ATRX/CDK1/STOML2	8
BP	GO:0051973	positive regulation of telomerase activity	8/2619	36/18670	0.1223	0.301	0.2258	MAPK3/HNRNPA2B1/MYC/HMBOX1/AURKB/PRKCQ/PARM1/HNRNPD	8
BP	GO:0060428	lung epithelium development	8/2619	36/18670	0.1223	0.301	0.2258	SOX9/BMP4/ADAMTSL2/RCN3/RBPJ/AIMP2/HOXA5/CREB1	8
BP	GO:0071634	regulation of transforming growth factor beta production	8/2619	36/18670	0.1223	0.301	0.2258	CD200/SMAD3/WNT11/TYROBP/XCL1/HIF1A/CREB1/ATF2	8
BP	GO:1903131	mononuclear cell differentiation	8/2619	36/18670	0.1223	0.301	0.2258	CTNNBIP1/BMP4/MED1/PPARG/MYC/VEGFA/IFI16/HOXA7	8
BP	GO:0000245	spliceosomal complex assembly	16/2619	84/18670	0.1229	0.3023	0.2267	SRPK1/SETX/CELF2/SF3B1/NOL3/CELF1/DDX23/SFSWAP/PTBP2/SCAF11/DDX1/SNRPD2/TXNL4A/YTHDC1/LUC7L/GEMIN2	16
BP	GO:0045445	myoblast differentiation	16/2619	84/18670	0.1229	0.3023	0.2267	PITX1/CXCL9/CXCL10/NOTCH1/MAP3K5/SOX9/MBNL3/SDC1/BMP4/MAML1/IGF1/RBPJ/TNFSF14/ID3/TCF7L2/DDIT3	16
BP	GO:0051492	regulation of stress fiber assembly	16/2619	84/18670	0.1229	0.3023	0.2267	SFRP1/SMAD3/PFN2/CORO2B/LIMCH1/WNT11/ROCK1/BBS4/PTGER4/S1PR1/PPM1E/CLASP1/MYOC/ALMS1/NF2/TAC1	16
BP	GO:0006479	protein methylation	31/2619	179/18670	0.1233	0.303	0.2272	MTF2/JARID2/SUZ12/WDR61/DNMT1/EZH2/ARID4B/METTL22/PRMT5/RLF/SETD5/LCMT1/KDM3A/SETMAR/TRMT112/SMYD2/AUTS2/WDR5B/SETD1B/ATRX/VCPKMT/SATB1/EED/PAXBP1/ARID4A/OGT/HEMK1/SETD2/PRDM4/SUV39H2/CXXC1	31
BP	GO:0008213	protein alkylation	31/2619	179/18670	0.1233	0.303	0.2272	MTF2/JARID2/SUZ12/WDR61/DNMT1/EZH2/ARID4B/METTL22/PRMT5/RLF/SETD5/LCMT1/KDM3A/SETMAR/TRMT112/SMYD2/AUTS2/WDR5B/SETD1B/ATRX/VCPKMT/SATB1/EED/PAXBP1/ARID4A/OGT/HEMK1/SETD2/PRDM4/SUV39H2/CXXC1	31
BP	GO:0030177	positive regulation of Wnt signaling pathway	31/2619	179/18670	0.1233	0.303	0.2272	TNFAIP3/SFRP1/GPC5/MACF1/SMAD3/ASPM/TNKS2/PSMB9/NLE1/EGFR/EGF/ZBED2/PLEKHA4/PSMC2/USP47/USP34/NFKB1/PSMB6/WLS/PSMC3/RBPJ/PIN1/USP8/PSMD8/LGR5/PSMB5/FRAT1/CSNK1E/PSMD10/CAPRIN2/UBR5	31
BP	GO:0001676	long-chain fatty acid metabolic process	20/2619	109/18670	0.1239	0.304	0.228	HPGDS/LTC4S/PTGS1/TBXAS1/MAPK3/EPHX2/SLC27A6/ACSL5/SLC27A5/GSTM4/HPGD/GPX4/PLA2G4C/SCP2/AKR1C3/PTGDS/ACOX1/ACOT8/CBR1/PLP1	20
BP	GO:0014897	striated muscle hypertrophy	20/2619	109/18670	0.1239	0.304	0.228	NOTCH1/JARID2/TNFRSF1B/IGFBP5/SMAD3/EZH2/HTR2B/ROCK1/RGS4/AGT/CTDP1/IGF1/MYOC/SORBS2/PIN1/P2RX4/PPP3CA/ATP2B4/AKAP13/CDK9	20
BP	GO:0032271	regulation of protein polymerization	37/2619	218/18670	0.1241	0.3045	0.2284	IQGAP2/ACTR3B/STMN2/ARPC1A/SNCA/TMOD1/CDC42EP3/ARL2/FCHSD2/PFN2/BAIAP2/NCK2/PINK1/ACTR3/CAPZA1/BIN1/MAPRE3/BBS4/DRG1/CDH5/TMOD2/CLASP1/FHOD3/MAGEL2/SCIN/CCR7/AP1AR/TMSB10/ARPC5L/AKAP9/RANGRF/CTTN/HIP1R/CYFIP1/PTK2B/ARFGEF1/ACTR2	37
BP	GO:0000271	polysaccharide biosynthetic process	15/2619	78/18670	0.1244	0.3048	0.2286	PPP1R3C/ENPP1/EGF/PGM1/EXT2/GSK3B/INSR/DYRK2/NFKB1/EXTL2/IGF1/PDGFB/HAS2/PASK/SORBS1	15
BP	GO:0001910	regulation of leukocyte mediated cytotoxicity	15/2619	78/18670	0.1244	0.3048	0.2286	HLA-C/DNASE1L3/RASGRP1/HLA-F/HLA-G/MICB/IL7R/HLA-A/PTPRC/HLA-B/HLA-E/CRTAM/TYROBP/XCL1/ULBP2	15
BP	GO:0006487	protein N-linked glycosylation	15/2619	78/18670	0.1244	0.3048	0.2286	MGAT4C/UBE2J1/TMEM258/B3GALNT1/DPM3/DPAGT1/DAD1/MAN1C1/B4GALT7/DHDDS/FUT8/DDOST/ALG6/PMM1/ASGR1	15
BP	GO:0014743	regulation of muscle hypertrophy	15/2619	78/18670	0.1244	0.3048	0.2286	NOTCH1/JARID2/TNFRSF1B/IGFBP5/SMAD3/ROCK1/RGS4/AGT/CTDP1/IGF1/PIN1/P2RX4/PPP3CA/ATP2B4/CDK9	15
BP	GO:0071166	ribonucleoprotein complex localization	23/2619	128/18670	0.1245	0.3049	0.2287	HNRNPA2B1/NXF3/NUP160/THOC2/NUP153/DDX39A/THOC1/TPR/NUP50/SEC13/NMD3/RANBP2/NXF1/SRSF4/NUP210/NUP43/NDC1/SETD2/YTHDC1/NCBP2/EIF6/NUP98/NUP62	23
BP	GO:0000209	protein polyubiquitination	51/2619	310/18670	0.1248	0.3055	0.2291	TNFAIP3/RNF125/DYSF/UBE2D4/FBXW7/SKP1/UBR2/TNKS2/PSMB9/AREL1/TRIP12/BARD1/NMI/BIRC2/CHFR/FBXO17/RNF111/PTPN22/FBXW12/PSMC2/KLHL3/RC3H2/UNKL/PELI1/UBE2E3/PSMB6/TRIM21/PSMC3/MAGEL2/RNF19B/LNPEP/PSMD8/UBB/NOD2/LONRF1/DTL/PSMB5/DDB2/RNF187/NFE2L1/IRF2BP1/PSMD10/TPP2/RNF14/TRIM32/UBR5/FBXO38/TRIM2/RNF34/NEDD4L/TRIM58	51
BP	GO:0031641	regulation of myelination	9/2619	42/18670	0.1252	0.3063	0.2297	PTN/TNFRSF1B/HGF/ITGAX/TNFRSF21/TYMP/KLK8/CST7/TENM4	9
BP	GO:0051154	negative regulation of striated muscle cell differentiation	9/2619	42/18670	0.1252	0.3063	0.2297	CXCL10/NOTCH1/CFLAR/EZH2/RGS4/CTDP1/XBP1/FZD7/BDNF	9
BP	GO:0051881	regulation of mitochondrial membrane potential	14/2619	72/18670	0.1257	0.3074	0.2306	GOT1/PID1/BAD/PINK1/TUSC2/TSPO/KDR/MYOC/UBB/ARL6IP5/SOD1/PYCR1/STOML2/PPA2	14
BP	GO:0048259	regulation of receptor-mediated endocytosis	19/2619	103/18670	0.1262	0.3084	0.2313	PLCG2/ANGPT1/CLU/USP46/SYT11/LRPAP1/EGF/SERPINE1/NTF3/HFE/MAGI2/SELE/HNRNPK/ARRB1/APOC1/CD63/PIK3CB/VEGFA/HIP1R	19
BP	GO:0055002	striated muscle cell development	30/2619	173/18670	0.1263	0.3085	0.2314	SIX1/DYSF/TMOD1/UCHL1/CFLAR/SGCB/SDC1/MYOM2/BMP4/GPX1/NEBL/MAML1/RGS4/AGT/CTDP1/IGF1/COMP/CCNB1/TMOD2/FHOD3/SORBS2/VEGFA/PIN1/CHRNB1/PPP3CA/AKAP13/CDK1/CXADR/SMO/MYH10	30
BP	GO:0021700	developmental maturation	47/2619	284/18670	0.1268	0.3088	0.2316	CDC25B/CEBPA/SEMA4D/IL15/PTH1R/CX3CR1/EPB42/PPARG/S1PR1/CDH5/TUSC2/NPR2/PTBP3/CD63/DLD/IGF1/CCNB1/ANG/CDKN1C/BRCA2/RBPJ/CDC20/MYOC/AXL/EREG/VEGFA/MTCH1/FERMT1/IRX5/HIF1A/HOXA5/ERCC2/SIX3/TYMS/ID2/GAL/CDKN1A/XBP1/PTK2B/ABHD2/SEZ6L/CAMK2B/BCL11A/DDIT3/DAZL/TRIM58/FBXO5	47
BP	GO:0009311	oligosaccharide metabolic process	10/2619	48/18670	0.1268	0.3088	0.2316	GAL3ST4/B3GALNT1/MAN2B2/ST3GAL2/MAN1B1/GM2A/FUT8/NEU1/GAA/ST8SIA2	10
BP	GO:0030850	prostate gland development	10/2619	48/18670	0.1268	0.3088	0.2316	SFRP1/NOTCH1/AR/SOX9/RXRA/BMP4/CYP7B1/ID4/SERPINF1/PSAP	10
BP	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	10/2619	48/18670	0.1268	0.3088	0.2316	BTC/EGFR/EGF/PTPN2/CHMP6/CBLB/ARHGEF7/HBEGF/EREG/NUP62	10
BP	GO:0045912	negative regulation of carbohydrate metabolic process	10/2619	48/18670	0.1268	0.3088	0.2316	SIK1/NUPR1/ENPP1/CBFA2T3/DDIT4/GSK3B/FAM3A/EP300/CRY1/PASK	10
BP	GO:0055023	positive regulation of cardiac muscle tissue growth	10/2619	48/18670	0.1268	0.3088	0.2316	NOTCH1/PIM1/ZFPM2/IGF1/TBX5/CCNB1/RBPJ/PIN1/CDK1/ERBB4	10
BP	GO:0055001	muscle cell development	32/2619	186/18670	0.1269	0.3088	0.2316	SIX1/DYSF/NOTCH1/TMOD1/UCHL1/CFLAR/SGCB/SDC1/MYOM2/BIN1/BMP4/GPX1/NEBL/MAML1/RGS4/AGT/CTDP1/IGF1/COMP/CCNB1/TMOD2/FHOD3/SORBS2/VEGFA/PIN1/CHRNB1/PPP3CA/AKAP13/CDK1/CXADR/SMO/MYH10	32
BP	GO:0042267	natural killer cell mediated cytotoxicity	12/2619	60/18670	0.1274	0.3088	0.2316	RASGRP1/HLA-F/HLA-G/MICB/RAB27A/SLAMF7/HLA-E/GZMB/CRTAM/VAMP7/ULBP2/CEBPG	12
BP	GO:0006636	unsaturated fatty acid biosynthetic process	11/2619	54/18670	0.1274	0.3088	0.2316	HPGDS/LTC4S/PTGS1/TBXAS1/ALOX5AP/DECR2/HPGD/SCD5/AKR1C3/PTGDS/CBR1	11
BP	GO:0010524	positive regulation of calcium ion transport into cytosol	11/2619	54/18670	0.1274	0.3088	0.2316	CXCL9/CXCL10/SNCA/SRI/CXCL11/GPER1/F2R/XCL1/CD19/P2RX4/CALCR	11
BP	GO:0001562	response to protozoan	6/2619	25/18670	0.1276	0.3088	0.2316	GBP2/IL4R/CD40/SLC11A1/BATF/TSPAN32	6
BP	GO:0003071	renal system process involved in regulation of systemic arterial blood pressure	6/2619	25/18670	0.1276	0.3088	0.2316	HSD11B2/CORO2B/F2R/AGT/PDGFB/EMP2	6
BP	GO:0009299	mRNA transcription	6/2619	25/18670	0.1276	0.3088	0.2316	MED1/EREG/HIF1A/FLNA/ATF4/DDIT3	6
BP	GO:0019430	removal of superoxide radicals	6/2619	25/18670	0.1276	0.3088	0.2316	GCH1/FBLN5/NQO1/NOS3/SOD1/PRDX2	6
BP	GO:0030325	adrenal gland development	6/2619	25/18670	0.1276	0.3088	0.2316	SMAD3/INSR/WNT11/TSPO/INSM1/CDKN1C	6
BP	GO:0030813	positive regulation of nucleotide catabolic process	6/2619	25/18670	0.1276	0.3088	0.2316	INSR/PFKFB3/IFNG/IGF1/HIF1A/PRKAA1	6
BP	GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway	6/2619	25/18670	0.1276	0.3088	0.2316	TNFAIP3/LILRA2/CARD8/TRIB1/LY86/PRDX2	6
BP	GO:0032616	interleukin-13 production	6/2619	25/18670	0.1276	0.3088	0.2316	TNFRSF21/HLA-E/LEF1/IL17RB/TNFSF4/IL17RA	6
BP	GO:0046856	phosphatidylinositol dephosphorylation	6/2619	25/18670	0.1276	0.3088	0.2316	MTMR4/MTMR9/SYNJ1/MTMR6/MTMR1/INPP5E	6
BP	GO:0051197	positive regulation of coenzyme metabolic process	6/2619	25/18670	0.1276	0.3088	0.2316	INSR/PFKFB3/IFNG/IGF1/HIF1A/PRKAA1	6
BP	GO:0060561	apoptotic process involved in morphogenesis	6/2619	25/18670	0.1276	0.3088	0.2316	NOTCH1/TNFRSF1B/FOXC1/LEF1/CRYAB/JAG2	6
BP	GO:1903306	negative regulation of regulated secretory pathway	6/2619	25/18670	0.1276	0.3088	0.2316	NOTCH1/HLA-F/FOXF1/RAP1B/IL13RA2/CCR2	6
BP	GO:2000353	positive regulation of endothelial cell apoptotic process	6/2619	25/18670	0.1276	0.3088	0.2316	HLA-G/CD40/GPER1/PRKCI/AKR1C3/CD40LG	6
BP	GO:2000679	positive regulation of transcription regulatory region DNA binding	6/2619	25/18670	0.1276	0.3088	0.2316	FOXC1/IFNG/IGF1/EP300/HMGA2/TWIST1	6
BP	GO:0030316	osteoclast differentiation	18/2619	97/18670	0.1284	0.3106	0.233	SFRP1/TREM2/TFRC/FBXW7/TCTA/GPR183/TNFRSF11A/IREB2/TCIRG1/CD81/IFNG/TYROBP/CA2/SNX10/CREB1/GLO1/CEBPB/SBNO2	18
BP	GO:0051591	response to cAMP	18/2619	97/18670	0.1284	0.3106	0.233	STAT1/IGFBP5/KCNQ1/NDUFS4/SDC1/BSG/STC1/BIRC2/FDX1/PENK/ITPR2/ASS1/CRHBP/CPS1/AKAP9/PTK2B/RAP1B/HSPA5	18
BP	GO:0006405	RNA export from nucleus	24/2619	135/18670	0.1295	0.3131	0.2348	HNRNPA2B1/NXF3/NUP160/THOC2/NUP153/DDX39A/THOC1/TPR/NUP50/SEC13/NMD3/RANBP2/NXF1/SRSF4/NUP210/HNRNPA1/NUP43/NDC1/SETD2/YTHDC1/NCBP2/EIF6/NUP98/NUP62	24
BP	GO:0007498	mesoderm development	24/2619	135/18670	0.1295	0.3131	0.2348	HOXA11/EYA2/JAK2/SECTM1/SMAD3/FOXC1/EXT2/MEST/BMP4/WNT11/PUS7/LEF1/TIE1/FOXF1/WLS/ZFPM2/SIX2/TLX2/VEGFA/SETD2/NF2/ETS2/SMO/HMGA2	24
BP	GO:1900180	regulation of protein localization to nucleus	21/2619	116/18670	0.1298	0.3136	0.2352	ZIC1/ECT2/ANGPT1/SMAD3/GSK3B/TPR/BMP4/NMD3/IFNG/MFHAS1/PIN1/FERMT1/NF2/TARDBP/NGFR/GTSE1/CDK1/FLNA/UBR5/SMO/NUP62	21
BP	GO:0048762	mesenchymal cell differentiation	37/2619	219/18670	0.1301	0.3141	0.2356	SFRP1/NOTCH1/FOLR1/STAT1/SOX9/SEMA4D/MAPK3/SMAD3/TMEM100/SEMA4A/FOXC1/HGF/SEMA3A/EZH2/GSK3B/BMP4/SEMA4C/HTR2B/WNT11/FAM172A/LEF1/LAMA5/SEMA3F/SIX2/TBX5/EFNB1/IL6/CLASP1/RBPJ/SEMA3E/PHACTR4/HIF1A/HAS2/ERBB4/SMO/HMGA2/TWIST1	37
BP	GO:0010631	epithelial cell migration	57/2619	351/18670	0.1308	0.3156	0.2367	PTN/NOTCH1/LGMN/SOX9/PRKD2/FBXW7/CXCL13/ANGPT1/MACF1/SEMA4A/SEMA3A/ADAM17/PFN2/STC1/ANGPT2/APOE/PRKX/PECAM1/AAMP/KIT/BMP4/CSNK2B/PPARG/GPX1/CD40/HSPB1/KRIT1/IFNG/PLK2/AGT/NOS3/RAB13/FGF18/KDR/MAP4K4/HBEGF/CLASP1/PDGFB/VEGFA/PLXND1/P2RX4/HMGB1/FERMT1/SCG2/MAP3K3/HIF1A/EMP2/HAS2/TAC1/CIB1/STAT5A/MAPRE2/PTK2B/SERPINF1/KANK2/ARSB/PIK3CA	57
BP	GO:0051494	negative regulation of cytoskeleton organization	26/2619	148/18670	0.1312	0.3167	0.2375	STMN2/SNCA/TMOD1/MDM1/FGF13/PFN2/CORO2B/CAPZA1/ARHGEF2/BBS4/S1PR1/CDH5/CHMP2A/TAOK1/TMOD2/CLASP1/FHOD3/MYOC/SCIN/TMSB10/KATNB1/CIB1/HIP1R/KAT2B/LIMA1/ARFGEF1	26
BP	GO:0044106	cellular amine metabolic process	23/2619	129/18670	0.1324	0.3193	0.2395	ALDH7A1/HAAO/SNCA/SLC7A11/PSMB9/IDO1/COMT/NQO1/AGMAT/SMS/PSMC2/MOXD1/GDE1/PSMB6/HDC/PSMC3/PSMD8/PSMB5/SRM/PSMD10/ATP2B4/HNMT/OAZ3	23
BP	GO:0071482	cellular response to light stimulus	23/2619	129/18670	0.1324	0.3193	0.2395	PTN/GPR88/MFAP4/ERCC1/ATR/METAP1/CHEK1/USP47/GUCA1A/MYC/AURKB/CASP9/RS1/DDB2/RUVBL2/PTPRK/METAP2/CDKN1A/N4BP1/EP300/CRY1/ATF4/RBL2	23
BP	GO:0061387	regulation of extent of cell growth	20/2619	110/18670	0.1325	0.3193	0.2395	SEMA4D/MACF1/SEMA4A/SEMA3A/FGF13/APOE/GSK3B/SEMA4C/EFNA5/SEMA3F/RND2/VEGFA/SEMA3E/CTTN/GOLGA4/TRPV2/CDKL5/CYFIP1/DSCAM/BDNF	20
BP	GO:0002028	regulation of sodium ion transport	16/2619	85/18670	0.1328	0.3199	0.2399	SIK1/SCN1B/ATP1B1/SNTA1/FXYD1/FXYD6/NETO2/KLHL24/ANK3/ADRB2/YWHAH/NOS3/P2RX4/RANGRF/ATP2B4/NEDD4L	16
BP	GO:1901343	negative regulation of vasculature development	32/2619	187/18670	0.1334	0.3212	0.2409	CXCL10/PTN/NOTCH1/STAT1/THBS4/HLA-G/SEMA4A/DNMT1/FOXC1/CX3CR1/SERPINE1/ANGPT2/BMP4/TNMD/PPARG/ROCK1/TIE1/KRIT1/PLK2/AGT/PML/PDGFB/SEMA3E/HOXA5/NGFR/THBS2/ATF2/FOXJ2/COL4A2/CCR2/GPR4/SERPINF1	32
BP	GO:1905475	regulation of protein localization to membrane	32/2619	187/18670	0.1334	0.3212	0.2409	GBP1/PTN/TREM2/GPC5/AR/CDH2/FIS1/SLC7A11/PID1/BAD/EGFR/PRNP/PRKCH/AP2M1/ERBB2/GZMB/VTI1B/PPP1R13B/ANK3/GPER1/CD81/YWHAH/IFNG/PRKCI/TP53BP2/TMEM59/VAMP7/GHSR/RANGRF/CIB1/LGALS3/SORBS1	32
BP	GO:0003401	axis elongation	7/2619	31/18670	0.1341	0.3224	0.2418	SIX1/SFRP1/SOX9/BMP4/WNT11/MAGI2/MED1	7
BP	GO:0009954	proximal/distal pattern formation	7/2619	31/18670	0.1341	0.3224	0.2418	HOXA11/HOXA10/HOXC10/EN1/HOXD9/SIX3/HOXC11	7
BP	GO:0010165	response to X-ray	7/2619	31/18670	0.1341	0.3224	0.2418	SFRP1/ERCC1/NIPBL/ATM/BRCA2/CDKN1A/HMGA2	7
BP	GO:1902186	regulation of viral release from host cell	7/2619	31/18670	0.1341	0.3224	0.2418	TRIM26/PC/TRIM21/CHMP2A/PML/TRIM32/VAPA	7
BP	GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	19/2619	104/18670	0.1351	0.3246	0.2435	NOTCH1/GOT1/ADAM17/NEO1/HFE/ING2/BMP4/GDF5/RNF111/CSNK2B/FKBP8/CDH5/CDKN1C/RBPJ/FERMT1/GDF9/EP300/INHBB/ZNF423	19
BP	GO:1901800	positive regulation of proteasomal protein catabolic process	19/2619	104/18670	0.1351	0.3246	0.2435	NUPR1/CEBPA/TREM2/FBXW7/CLU/HERPUD1/CBFA2T3/GSK3B/CHFR/PSMC2/PLK2/TRIB1/DET1/CSNK1A1/RNF19B/CSNK1E/EDEM1/PSMD10/RNF14	19
BP	GO:0072401	signal transduction involved in DNA integrity checkpoint	14/2619	73/18670	0.1366	0.3275	0.2457	CRADD/CHEK2/CHEK1/ATM/PLK2/CCNB1/PML/DTL/BABAM1/GTSE1/CDK1/CDKN1A/EP300/RBL2	14
BP	GO:0072422	signal transduction involved in DNA damage checkpoint	14/2619	73/18670	0.1366	0.3275	0.2457	CRADD/CHEK2/CHEK1/ATM/PLK2/CCNB1/PML/DTL/BABAM1/GTSE1/CDK1/CDKN1A/EP300/RBL2	14
BP	GO:0051147	regulation of muscle cell differentiation	31/2619	181/18670	0.1367	0.3275	0.2457	CXCL9/SIK1/CXCL10/NOTCH1/CDH2/IL4R/CFLAR/DNMT1/EZH2/SMARCD3/KIT/BMP4/GPER1/MAML1/RGS4/MAPK11/CTDP1/IGF1/RBPJ/EREG/PDGFB/PIN1/CAMK1/TCF3/TNFSF14/AKAP13/TRIM32/XBP1/CDK9/FZD7/BDNF	31
BP	GO:0003156	regulation of animal organ formation	8/2619	37/18670	0.1379	0.3275	0.2457	SIX1/HOXA11/NOTCH1/AR/PIM1/BMP4/TBX5/HOXC11	8
BP	GO:0006623	protein targeting to vacuole	8/2619	37/18670	0.1379	0.3275	0.2457	VPS13C/CLU/VPS37C/ZFYVE16/GNPTAB/VTI1B/VAMP7/AP4M1	8
BP	GO:0010614	negative regulation of cardiac muscle hypertrophy	8/2619	37/18670	0.1379	0.3275	0.2457	NOTCH1/JARID2/TNFRSF1B/SMAD3/RGS4/CTDP1/P2RX4/ATP2B4	8
BP	GO:0043114	regulation of vascular permeability	8/2619	37/18670	0.1379	0.3275	0.2457	TACR2/ANGPT1/DDAH1/CTNNBIP1/CDH5/VEGFA/ARHGAP35/CXCR2	8
BP	GO:0043243	positive regulation of protein complex disassembly	8/2619	37/18670	0.1379	0.3275	0.2457	SETX/STMN2/UVRAG/INSR/ADRB2/SPAST/KATNB1/CLEC16A	8
BP	GO:0048846	axon extension involved in axon guidance	8/2619	37/18670	0.1379	0.3275	0.2457	SEMA4D/SEMA4A/SEMA3A/SEMA4C/SEMA3F/VEGFA/SEMA3E/DSCAM	8
BP	GO:0051567	histone H3-K9 methylation	8/2619	37/18670	0.1379	0.3275	0.2457	JARID2/DNMT1/ARID4B/SETD5/KDM3A/ATRX/ARID4A/SUV39H2	8
BP	GO:1902284	neuron projection extension involved in neuron projection guidance	8/2619	37/18670	0.1379	0.3275	0.2457	SEMA4D/SEMA4A/SEMA3A/SEMA4C/SEMA3F/VEGFA/SEMA3E/DSCAM	8
BP	GO:1905314	semi-lunar valve development	8/2619	37/18670	0.1379	0.3275	0.2457	NOTCH1/TNFRSF1B/SOX9/BMP4/ROCK1/NOS3/RBPJ/TWIST1	8
BP	GO:0019748	secondary metabolic process	13/2619	67/18670	0.1382	0.3275	0.2457	CBS/AKR1B1/AKR1B10/AKR7A3/SLC7A11/BDH2/ARL1/AKR7A2/MPST/AKR1C3/DCT/AKR1C4/TH	13
BP	GO:0002320	lymphoid progenitor cell differentiation	5/2619	20/18670	0.1382	0.3275	0.2457	NOTCH1/SOS1/KIT/BMP4/BATF	5
BP	GO:0002374	cytokine secretion involved in immune response	5/2619	20/18670	0.1382	0.3275	0.2457	TNFRSF1B/MAPK3/ANGPT1/TNFRSF14/NOD2	5
BP	GO:0003323	type B pancreatic cell development	5/2619	20/18670	0.1382	0.3275	0.2457	BAD/GSK3B/BMP4/INSM1/SMO	5
BP	GO:0006071	glycerol metabolic process	5/2619	20/18670	0.1382	0.3275	0.2457	DYSF/GOT1/GK/PCK2/COQ2	5
BP	GO:0006677	glycosylceramide metabolic process	5/2619	20/18670	0.1382	0.3275	0.2457	UGCG/PRKAA1/FA2H/PSAP/B4GALT3	5
BP	GO:0010560	positive regulation of glycoprotein biosynthetic process	5/2619	20/18670	0.1382	0.3275	0.2457	IL15/IGF1/CCR7/TCF7L2/ARFGEF1	5
BP	GO:0030220	platelet formation	5/2619	20/18670	0.1382	0.3275	0.2457	NBEAL2/CASP9/CIB1/EP300/ACTN1	5
BP	GO:0032462	regulation of protein homooligomerization	5/2619	20/18670	0.1382	0.3275	0.2457	CLU/APOE/CRYAB/PEX14/RIOK3	5
BP	GO:0032793	positive regulation of CREB transcription factor activity	5/2619	20/18670	0.1382	0.3275	0.2457	CD200/PRKD2/ADCY1/VEGFA/CRTC3	5
BP	GO:0033194	response to hydroperoxide	5/2619	20/18670	0.1382	0.3275	0.2457	JAK2/CD38/GPX3/GPX1/CHUK	5
BP	GO:0034143	regulation of toll-like receptor 4 signaling pathway	5/2619	20/18670	0.1382	0.3275	0.2457	TNFAIP3/LILRA2/PTPN22/PELI1/MFHAS1	5
BP	GO:0035458	cellular response to interferon-beta	5/2619	20/18670	0.1382	0.3275	0.2457	AIM2/STAT1/IRF1/NDUFA13/IFI16	5
BP	GO:0036065	fucosylation	5/2619	20/18670	0.1382	0.3275	0.2457	FUT1/RFNG/POFUT1/FUT8/FUT4	5
BP	GO:0042474	middle ear morphogenesis	5/2619	20/18670	0.1382	0.3275	0.2457	SIX1/NAGLU/PRKRA/OSR2/SIX2	5
BP	GO:0043371	negative regulation of CD4-positive, alpha-beta T cell differentiation	5/2619	20/18670	0.1382	0.3275	0.2457	IL4R/RUNX3/RC3H2/TNFSF4/HMGB1	5
BP	GO:0043586	tongue development	5/2619	20/18670	0.1382	0.3275	0.2457	SIX1/EGFR/KIT/LEF1/HDAC1	5
BP	GO:0046823	negative regulation of nucleocytoplasmic transport	5/2619	20/18670	0.1382	0.3275	0.2457	ANGPT1/BARD1/NUP153/TPR/FERMT1	5
BP	GO:0046931	pore complex assembly	5/2619	20/18670	0.1382	0.3275	0.2457	BAD/NUP153/NDC1/GSDMD/NUP98	5
BP	GO:0048670	regulation of collateral sprouting	5/2619	20/18670	0.1382	0.3275	0.2457	SEMA4D/FGF13/EFNA5/RND2/BDNF	5
BP	GO:0060039	pericardium development	5/2619	20/18670	0.1382	0.3275	0.2457	NOTCH1/SMAD3/SOS1/TBX5/SETD2	5
BP	GO:0097709	connective tissue replacement	5/2619	20/18670	0.1382	0.3275	0.2457	ROCK1/F2R/PPP3CA/HIF1A/TIMP1	5
BP	GO:1901673	regulation of mitotic spindle assembly	5/2619	20/18670	0.1382	0.3275	0.2457	TPR/DRG1/CHMP2A/SMC1A/CHMP1B	5
BP	GO:1902993	positive regulation of amyloid precursor protein catabolic process	5/2619	20/18670	0.1382	0.3275	0.2457	CLU/GSAP/SPON1/IFNG/EPHA4	5
BP	GO:0007613	memory	21/2619	117/18670	0.1384	0.3277	0.2458	BRINP1/PTN/LGMN/FGF13/B4GALT2/ITGA5/COMT/PRNP/CX3CR1/APOE/INSR/NTF3/PLK2/KLK8/ADCY1/TAC1/CREB1/CEBPB/SERPINF1/BDNF/TH	21
BP	GO:0032259	methylation	59/2619	366/18670	0.1388	0.3287	0.2465	MTF2/JARID2/BHMT2/SUZ12/GAMT/PEMT/WDR61/DNMT1/EZH2/ARID4B/ATF7IP/HSD17B10/COMT/METTL8/TARBP1/METTL22/PRMT5/CMTR1/RLF/SETD5/LCMT1/KDM3A/SETMAR/TRMT112/SMYD2/AUTS2/GATAD2A/RBM15/WDR5B/SETD1B/MYC/ATRX/AHCY/METTL4/PRDM1/VCPKMT/SATB1/EED/DIMT1/PAXBP1/ARID4A/OGT/HEMK1/SETD2/PRDM4/SUV39H2/TYMS/PRDM10/HNMT/CXXC1/TFB2M/PIWIL2/BAZ2A/TRMT5/METTL5/MEPCE/NSUN6/PIK3CA/TRMT13	59
BP	GO:0006027	glycosaminoglycan catabolic process	12/2619	61/18670	0.1394	0.3295	0.2471	FUCA1/GPC5/GUSB/SDC1/HMMR/NAGLU/CD44/HEXA/VCAN/SGSH/KERA/ARSB	12
BP	GO:0032370	positive regulation of lipid transport	12/2619	61/18670	0.1394	0.3295	0.2471	NFKBIA/TNFRSF11A/APOE/NR1H2/SCP2/ATP8A1/P2RX4/PLA2R1/TMF1/TAC1/GAL/FABP3	12
BP	GO:0045123	cellular extravasation	12/2619	61/18670	0.1394	0.3295	0.2471	IL27RA/CX3CR1/PECAM1/PLVAP/SELE/ROCK1/ITGB7/PTGER4/ELANE/PIK3CD/GOLPH3/CCR2	12
BP	GO:0000413	protein peptidyl-prolyl isomerization	9/2619	43/18670	0.1398	0.3295	0.2471	PPIC/FKBP8/RANBP2/NKTR/PIN1/FKBP10/PPIE/PPIB/PPIH	9
BP	GO:0010824	regulation of centrosome duplication	9/2619	43/18670	0.1398	0.3295	0.2471	MDM1/CHORDC1/PLK2/CHMP2A/ALMS1/CHMP1B/KAT2B/SPICE1/NUP62	9
BP	GO:0046460	neutral lipid biosynthetic process	9/2619	43/18670	0.1398	0.3295	0.2471	SIK1/FBXW7/GK/NR1H2/ANG/PCK2/PLCE1/LPL/LPIN1	9
BP	GO:0046461	neutral lipid catabolic process	9/2619	43/18670	0.1398	0.3295	0.2471	PNPLA4/LIPC/ABHD6/APOE/CPS1/LPL/FABP7/FABP3/ABHD2	9
BP	GO:0046463	acylglycerol biosynthetic process	9/2619	43/18670	0.1398	0.3295	0.2471	SIK1/FBXW7/GK/NR1H2/ANG/PCK2/PLCE1/LPL/LPIN1	9
BP	GO:0046464	acylglycerol catabolic process	9/2619	43/18670	0.1398	0.3295	0.2471	PNPLA4/LIPC/ABHD6/APOE/CPS1/LPL/FABP7/FABP3/ABHD2	9
BP	GO:0050850	positive regulation of calcium-mediated signaling	9/2619	43/18670	0.1398	0.3295	0.2471	TREM2/CAMTA1/ADA/ZAP70/CD3E/TRAT1/IGF1/P2RX4/CIB1	9
BP	GO:0051602	response to electrical stimulus	9/2619	43/18670	0.1398	0.3295	0.2471	TACR2/S100A13/NQO1/FZD3/NTRK1/AKAP9/CYFIP1/HNRNPD/TH	9
BP	GO:0071364	cellular response to epidermal growth factor stimulus	9/2619	43/18670	0.1398	0.3295	0.2471	SOX9/CFLAR/FOXC1/EGFR/BAIAP2/ERBB2/MED1/ZFP36L2/ERBB4	9
BP	GO:0002090	regulation of receptor internalization	11/2619	55/18670	0.1403	0.3297	0.2473	PLCG2/ANGPT1/USP46/LRPAP1/EGF/NTF3/MAGI2/SELE/ARRB1/CD63/VEGFA	11
BP	GO:0002886	regulation of myeloid leukocyte mediated immunity	11/2619	55/18670	0.1403	0.3297	0.2473	DNASE1L3/IL4R/HLA-E/FGR/FOXF1/RAC2/VAMP7/DDX1/DDX21/IL13RA2/CCR2	11
BP	GO:0006576	cellular biogenic amine metabolic process	11/2619	55/18670	0.1403	0.3297	0.2473	ALDH7A1/HAAO/IDO1/AGMAT/SMS/MOXD1/GDE1/HDC/SRM/HNMT/OAZ3	11
BP	GO:0010823	negative regulation of mitochondrion organization	11/2619	55/18670	0.1403	0.3297	0.2473	CLU/HGF/PINK1/NOL3/TMEM14A/GPX1/TSPO/IGF1/PSMD10/ACAA2/CLEC16A	11
BP	GO:0016233	telomere capping	11/2619	55/18670	0.1403	0.3297	0.2473	DCLRE1C/MAPK3/ERCC1/NBN/TNKS2/ATM/AURKB/PRKCQ/RAD50/NABP2/HNRNPD	11
BP	GO:0003044	regulation of systemic arterial blood pressure mediated by a chemical signal	10/2619	49/18670	0.1405	0.3297	0.2473	CPA3/HSD11B2/CMA1/F2R/ADRB2/AGT/NOS3/SLC2A5/CTSG/CORIN	10
BP	GO:0008347	glial cell migration	10/2619	49/18670	0.1405	0.3297	0.2473	TREM2/GPR183/SYNE2/NDN/CX3CR1/CERS2/TSPO/EPHA4/P2RX4/CCR2	10
BP	GO:0034260	negative regulation of GTPase activity	10/2619	49/18670	0.1405	0.3297	0.2473	IQGAP2/ARL2/CDC42SE1/RRP1B/BBS4/ARRB1/PTPRN2/TMED2/RHOH/ARFGEF1	10
BP	GO:0051445	regulation of meiotic cell cycle	10/2619	49/18670	0.1405	0.3297	0.2473	CDC25B/ASPM/INSR/NPR2/CDC20/YTHDC2/RAD1/PIWIL2/DAZL/FBXO5	10
BP	GO:0097300	programmed necrotic cell death	10/2619	49/18670	0.1405	0.3297	0.2473	MAP3K5/BIRC3/SLC25A4/FAS/CFLAR/BIRC2/ARHGEF2/IRF3/PELI1/CYLD	10
BP	GO:1903018	regulation of glycoprotein metabolic process	10/2619	49/18670	0.1405	0.3297	0.2473	IL15/NECAB3/IGF1/TMEM59/HBEGF/ITM2C/CCR7/TCF7L2/ACOT8/ARFGEF1	10
BP	GO:0014896	muscle hypertrophy	20/2619	111/18670	0.1414	0.3318	0.2489	NOTCH1/JARID2/TNFRSF1B/IGFBP5/SMAD3/EZH2/HTR2B/ROCK1/RGS4/AGT/CTDP1/IGF1/MYOC/SORBS2/PIN1/P2RX4/PPP3CA/ATP2B4/AKAP13/CDK9	20
BP	GO:0090130	tissue migration	58/2619	360/18670	0.1422	0.3333	0.25	PTN/NOTCH1/LGMN/SOX9/PRKD2/FBXW7/CXCL13/ANGPT1/MACF1/SEMA4A/SEMA3A/ADAM17/PFN2/STC1/ANGPT2/APOE/PRKX/PECAM1/AAMP/KIT/BMP4/CSNK2B/PPARG/GPX1/CD40/HSPB1/FOXF1/KRIT1/IFNG/PLK2/AGT/NOS3/RAB13/FGF18/KDR/MAP4K4/HBEGF/CLASP1/PDGFB/VEGFA/PLXND1/P2RX4/HMGB1/FERMT1/SCG2/MAP3K3/HIF1A/EMP2/HAS2/TAC1/CIB1/STAT5A/MAPRE2/PTK2B/SERPINF1/KANK2/ARSB/PIK3CA	58
BP	GO:0048813	dendrite morphogenesis	25/2619	143/18670	0.1422	0.3333	0.25	PTN/SEMA4D/TNIK/SS18L1/SEMA3A/DOCK10/BAIAP2/ZNF365/GSK3B/TRAK1/PARP6/SIPA1L1/YWHAH/CHRNA3/VAMP7/TLX2/EPHA4/PPP3CA/ABI1/CDKL5/CAPRIN2/DSCAM/CAMK2B/ACTR2/NEDD4L	25
BP	GO:0019724	B cell mediated immunity	37/2619	221/18670	0.1425	0.334	0.2505	C7/PARP3/TFRC/IL27RA/ERCC1/CLU/NBN/HLA-G/SUSD4/IL4R/PTPRC/THOC1/HLA-E/IGLV1-44/IGHM/CD28/CFI/CD40/GCNT3/TCIRG1/CD81/TRBC1/CR1/CD27/XCL1/CD19/HLA-DQB1/TNFSF4/C4BPB/BATF/IGLL5/IGLC1/MBL2/BCL10/IL13RA2/TLR8/CD40LG	37
BP	GO:0001942	hair follicle development	16/2619	86/18670	0.143	0.3349	0.2512	NOTCH1/SOX9/IGFBP5/SOS1/EGFR/FZD3/LAMA5/RBPJ/DKK4/LGR5/FERMT1/ERCC2/HDAC1/GAL/FZD6/SMO	16
BP	GO:0034637	cellular carbohydrate biosynthetic process	16/2619	86/18670	0.143	0.3349	0.2512	AKR1B1/PPP1R3C/ENPP1/GOT1/PGM1/EXT2/GSK3B/INSR/DYRK2/EXTL2/IGF1/PCK2/HAS2/ISYNA1/PASK/SORBS1	16
BP	GO:0030856	regulation of epithelial cell differentiation	27/2619	156/18670	0.1431	0.3349	0.2512	NOTCH1/STAT1/SOX9/APOLD1/TMEM100/FOXC1/NCOA3/EZH2/BAD/NOTCH4/SERPINE1/PRKCH/PRKX/GSK3B/BMP4/MED1/ROCK1/CDH5/IFNG/MAFF/CDKN1C/VEGFA/FOXJ2/HOXA7/CEBPB/SMO/REG3A	27
BP	GO:0048634	regulation of muscle organ development	27/2619	156/18670	0.1431	0.3349	0.2512	SIX1/NOTCH1/JARID2/SMAD3/RBP4/PIM1/BMP4/FGF20/LEF1/RGS4/ZFPM2/MAPK11/CTDP1/IGF1/TBX5/CCNB1/RBPJ/PIN1/PRKAA1/CREB1/CDK1/LUC7L/ERBB4/FZD7/CENPF/TWIST1/NR1D2	27
BP	GO:0043462	regulation of ATPase activity	15/2619	80/18670	0.1455	0.3404	0.2553	ATP1B1/DNAL4/GABARAPL2/PFN2/DNAJC1/DNAJA1/MYL3/NCAPH/SETMAR/TOR1AIP1/VCPKMT/MYL4/HSPA2/DNAJC24/NAPA	15
BP	GO:0090132	epithelium migration	57/2619	354/18670	0.1456	0.3404	0.2553	PTN/NOTCH1/LGMN/SOX9/PRKD2/FBXW7/CXCL13/ANGPT1/MACF1/SEMA4A/SEMA3A/ADAM17/PFN2/STC1/ANGPT2/APOE/PRKX/PECAM1/AAMP/KIT/BMP4/CSNK2B/PPARG/GPX1/CD40/HSPB1/KRIT1/IFNG/PLK2/AGT/NOS3/RAB13/FGF18/KDR/MAP4K4/HBEGF/CLASP1/PDGFB/VEGFA/PLXND1/P2RX4/HMGB1/FERMT1/SCG2/MAP3K3/HIF1A/EMP2/HAS2/TAC1/CIB1/STAT5A/MAPRE2/PTK2B/SERPINF1/KANK2/ARSB/PIK3CA	57
BP	GO:0042180	cellular ketone metabolic process	41/2619	248/18670	0.1469	0.3409	0.2557	AKR1B1/PDK2/AKR1B10/SNCA/ERLIN2/SLC7A11/DHRS9/PSMB9/IDO1/COMT/NQO1/CYP11A1/COQ6/GSTZ1/PSMC2/PPARG/AKR7A2/OXCT1/APOC1/PSMB6/WDTC1/PSMC3/NR1H2/GHSR/EGR1/AKR1C3/PDK1/PSMD8/PSMB5/CYP4F11/NFE2L1/COQ9/PSMD10/ATP2B4/GLO1/EIF6/COQ2/FABP3/AKR1C4/OAZ3/TWIST1	41
BP	GO:0009451	RNA modification	28/2619	163/18670	0.1472	0.3409	0.2557	ADAR/FTO/HSD17B10/METTL8/TARBP1/NHP2/APOBEC3C/CMTR1/ELP5/PUS7/JMJD6/TRMT112/RBM15/ELP3/APOBEC3B/DIMT1/ADARB2/PUS1/DUS4L/SEPHS1/TFB2M/OSGEP/TRMT5/TSR3/MEPCE/NSUN6/THUMPD1/TRMT13	28
BP	GO:0006516	glycoprotein catabolic process	6/2619	26/18670	0.1473	0.3409	0.2557	FBXO17/NGLY1/MAN1B1/MMP12/EDEM1/SGSH	6
BP	GO:0031954	positive regulation of protein autophosphorylation	6/2619	26/18670	0.1473	0.3409	0.2557	TOM1L1/NBN/RAP2C/PDGFB/VEGFA/RAD50	6
BP	GO:0034453	microtubule anchoring	6/2619	26/18670	0.1473	0.3409	0.2557	CEP350/BBS4/FGFR1OP/PCM1/CLASP1/PEX14	6
BP	GO:0048596	embryonic camera-type eye morphogenesis	6/2619	26/18670	0.1473	0.3409	0.2557	ARID1A/ALDH1A3/PHACTR4/SIX3/TH/TWIST1	6
BP	GO:0048843	negative regulation of axon extension involved in axon guidance	6/2619	26/18670	0.1473	0.3409	0.2557	SEMA4D/SEMA4A/SEMA3A/SEMA4C/SEMA3F/SEMA3E	6
BP	GO:0051125	regulation of actin nucleation	6/2619	26/18670	0.1473	0.3409	0.2557	FCHSD2/MAGEL2/SCIN/AP1AR/HIP1R/CYFIP1	6
BP	GO:0072539	T-helper 17 cell differentiation	6/2619	26/18670	0.1473	0.3409	0.2557	MALT1/RORA/RC3H2/LY9/IL6/BATF	6
BP	GO:1900120	regulation of receptor binding	6/2619	26/18670	0.1473	0.3409	0.2557	PTPRF/HFE/LEF1/LDOC1/RUVBL2/BDNF	6
BP	GO:1903203	regulation of oxidative stress-induced neuron death	6/2619	26/18670	0.1473	0.3409	0.2557	FBXW7/SLC7A11/PINK1/MCL1/HIF1A/ATF4	6
BP	GO:1903579	negative regulation of ATP metabolic process	6/2619	26/18670	0.1473	0.3409	0.2557	NUPR1/SNCA/CBFA2T3/DDIT4/PID1/TSPO	6
BP	GO:0051145	smooth muscle cell differentiation	14/2619	74/18670	0.1479	0.3409	0.2557	SIX1/NOTCH1/SOX9/DNMT1/SGCB/SMARCD3/KIT/BMP4/GPER1/FOXF1/COMP/EREG/PDGFB/VEGFA	14
BP	GO:0072395	signal transduction involved in cell cycle checkpoint	14/2619	74/18670	0.1479	0.3409	0.2557	CRADD/CHEK2/CHEK1/ATM/PLK2/CCNB1/PML/DTL/BABAM1/GTSE1/CDK1/CDKN1A/EP300/RBL2	14
BP	GO:0001325	formation of extrachromosomal circular DNA	4/2619	15/18670	0.1484	0.3409	0.2557	ERCC1/NBN/DNA2/WRN	4
BP	GO:0002467	germinal center formation	4/2619	15/18670	0.1484	0.3409	0.2557	TNFAIP3/CXCL13/ADAM17/ADA	4
BP	GO:0002716	negative regulation of natural killer cell mediated immunity	4/2619	15/18670	0.1484	0.3409	0.2557	HLA-F/HLA-G/HLA-E/CD96	4
BP	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	4/2619	15/18670	0.1484	0.3409	0.2557	UQCR10/CYC1/UQCRQ/UQCRC1	4
BP	GO:0010561	negative regulation of glycoprotein biosynthetic process	4/2619	15/18670	0.1484	0.3409	0.2557	TMEM59/HBEGF/ITM2C/ACOT8	4
BP	GO:0014874	response to stimulus involved in regulation of muscle adaptation	4/2619	15/18670	0.1484	0.3409	0.2557	SGCA/MTMR4/NOL3/AGT	4
BP	GO:0030730	sequestering of triglyceride	4/2619	15/18670	0.1484	0.3409	0.2557	ENPP1/OSBPL8/PPARG/LPL	4
BP	GO:0032239	regulation of nucleobase-containing compound transport	4/2619	15/18670	0.1484	0.3409	0.2557	NUP153/TPR/SETD2/NCBP2	4
BP	GO:0032486	Rap protein signal transduction	4/2619	15/18670	0.1484	0.3409	0.2557	TIMP2/RAP2C/PLK2/RAP1B	4
BP	GO:0032736	positive regulation of interleukin-13 production	4/2619	15/18670	0.1484	0.3409	0.2557	HLA-E/IL17RB/TNFSF4/IL17RA	4
BP	GO:0033689	negative regulation of osteoblast proliferation	4/2619	15/18670	0.1484	0.3409	0.2557	SFRP1/NELL1/SMAD3/ATRAID	4
BP	GO:0034134	toll-like receptor 2 signaling pathway	4/2619	15/18670	0.1484	0.3409	0.2557	TNFAIP3/RIPK2/TNIP2/MFHAS1	4
BP	GO:0034310	primary alcohol catabolic process	4/2619	15/18670	0.1484	0.3409	0.2557	AKR1B10/AKR1C3/SULT1A2/ALDH3B1	4
BP	GO:0034349	glial cell apoptotic process	4/2619	15/18670	0.1484	0.3409	0.2557	TNFRSF21/PRKCH/PRKCI/CASP9	4
BP	GO:0043249	erythrocyte maturation	4/2619	15/18670	0.1484	0.3409	0.2557	EPB42/PTBP3/ERCC2/TRIM58	4
BP	GO:0045073	regulation of chemokine biosynthetic process	4/2619	15/18670	0.1484	0.3409	0.2557	ELANE/IFNG/IL6/EGR1	4
BP	GO:0045342	MHC class II biosynthetic process	4/2619	15/18670	0.1484	0.3409	0.2557	JAK2/IFNG/SLC11A1/XBP1	4
BP	GO:0045360	regulation of interleukin-1 biosynthetic process	4/2619	15/18670	0.1484	0.3409	0.2557	JAK2/IFNG/EGR1/TYROBP	4
BP	GO:0045475	locomotor rhythm	4/2619	15/18670	0.1484	0.3409	0.2557	NAGLU/EGR1/NCOR1/ID2	4
BP	GO:0048569	post-embryonic animal organ development	4/2619	15/18670	0.1484	0.3409	0.2557	EFEMP1/ERCC1/BCL11B/VEGFA	4
BP	GO:0051127	positive regulation of actin nucleation	4/2619	15/18670	0.1484	0.3409	0.2557	FCHSD2/MAGEL2/SCIN/CYFIP1	4
BP	GO:0051299	centrosome separation	4/2619	15/18670	0.1484	0.3409	0.2557	NDE1/CHEK1/KIF11/NUP62	4
BP	GO:0055089	fatty acid homeostasis	4/2619	15/18670	0.1484	0.3409	0.2557	GOT1/APOE/PRKAA1/XBP1	4
BP	GO:0060253	negative regulation of glial cell proliferation	4/2619	15/18670	0.1484	0.3409	0.2557	PTN/NOTCH1/CERS2/TSPO	4
BP	GO:0060339	negative regulation of type I interferon-mediated signaling pathway	4/2619	15/18670	0.1484	0.3409	0.2557	ADAR/SAMHD1/PTPN2/MMP12	4
BP	GO:0060766	negative regulation of androgen receptor signaling pathway	4/2619	15/18670	0.1484	0.3409	0.2557	SFRP1/PHB/NCOR1/HDAC1	4
BP	GO:0071474	cellular hyperosmotic response	4/2619	15/18670	0.1484	0.3409	0.2557	AKR1B1/ARHGEF2/MICU1/LETM1	4
BP	GO:0072283	metanephric renal vesicle morphogenesis	4/2619	15/18670	0.1484	0.3409	0.2557	STAT1/BMP4/SIX2/SMO	4
BP	GO:0090656	t-circle formation	4/2619	15/18670	0.1484	0.3409	0.2557	ERCC1/NBN/DNA2/WRN	4
BP	GO:0090737	telomere maintenance via telomere trimming	4/2619	15/18670	0.1484	0.3409	0.2557	ERCC1/NBN/DNA2/WRN	4
BP	GO:1900037	regulation of cellular response to hypoxia	4/2619	15/18670	0.1484	0.3409	0.2557	CHCHD2/DDAH1/PINK1/NOL3	4
BP	GO:1902187	negative regulation of viral release from host cell	4/2619	15/18670	0.1484	0.3409	0.2557	TRIM26/TRIM21/PML/TRIM32	4
BP	GO:1903358	regulation of Golgi organization	4/2619	15/18670	0.1484	0.3409	0.2557	MAPK3/PDE4DIP/EHD3/AKAP9	4
BP	GO:2000484	positive regulation of interleukin-8 secretion	4/2619	15/18670	0.1484	0.3409	0.2557	F2R/CD58/CD2/FCN1	4
BP	GO:0035924	cellular response to vascular endothelial growth factor stimulus	13/2619	68/18670	0.1502	0.3436	0.2577	NOTCH1/SPHK1/GAS1/PRKD2/PGF/FOXC1/HSPB1/CD63/KDR/VEGFA/ADAMTS3/MAPKAPK2/VEGFB	13
BP	GO:0003073	regulation of systemic arterial blood pressure	17/2619	93/18670	0.1506	0.3436	0.2577	AR/CPA3/DDAH1/HSD11B2/CORO2B/CMA1/BBS4/F2R/ADRB2/POSTN/AGT/NOS3/PDGFB/SLC2A5/EMP2/CTSG/CORIN	17
BP	GO:0034248	regulation of cellular amide metabolic process	76/2619	483/18670	0.152	0.3436	0.2577	PDK2/SPHK1/CCL5/IGFBP5/MAPK3/SNCA/CLU/CIRBP/SLC7A11/METAP1/FTO/IGF2BP3/CTSA/PRNP/NCK2/PUM2/PINK1/NOTCH4/APOE/IREB2/MTRF1/CDK4/TPR/BIN1/UQCC1/RXRA/DNAJC1/ERBB2/GSAP/SPON1/PUS7/CELF1/GSTZ1/CD28/ROCK1/LTN1/HSPB1/IFNG/RMND1/TIA1/IGF1/LARP4/ANG/IL6/POLR2G/PDK1/SECISBP2L/EIF2S3/TRAP1/EPHA4/PIN1/COA3/DIO2/ZFP36L2/MKNK2/DNAJC3/DDX1/TMED10/AGO3/PRKAA1/TYMS/NCBP2/LARP6/EIF6/NGRN/CYFIP1/CAPRIN2/PIWIL2/RPS6KA1/PTK2B/HNRNPD/ATF4/DNAJC24/PASK/DAZL/NEMF	76
BP	GO:0003407	neural retina development	12/2619	62/18670	0.1521	0.3436	0.2577	PTN/DIO3/SOX9/SMARCD3/GPM6A/ROM1/RS1/IRX5/ATP2B4/SIX3/DSCAM/ATP2B1	12
BP	GO:0006220	pyrimidine nucleotide metabolic process	12/2619	62/18670	0.1521	0.3436	0.2577	NME4/NME7/AGPAT1/ENTPD4/NME5/AGPAT5/TDG/NME3/DCTD/CTPS1/TYMS/PRPS1	12
BP	GO:0006521	regulation of cellular amino acid metabolic process	12/2619	62/18670	0.1521	0.3436	0.2577	SLC7A11/PSMB9/COMT/NQO1/PSMC2/PSMB6/PSMC3/PSMD8/PSMB5/PSMD10/ATP2B4/OAZ3	12
BP	GO:0055025	positive regulation of cardiac muscle tissue development	12/2619	62/18670	0.1521	0.3436	0.2577	NOTCH1/PIM1/BMP4/ZFPM2/IGF1/TBX5/CCNB1/RBPJ/PIN1/CREB1/CDK1/ERBB4	12
BP	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	12/2619	62/18670	0.1521	0.3436	0.2577	MAP3K5/HERPUD1/NCK2/CASP4/CREB3/PTPN2/APAF1/PML/XBP1/CEBPB/ATF4/DDIT3	12
BP	GO:0070265	necrotic cell death	12/2619	62/18670	0.1521	0.3436	0.2577	MAP3K5/BIRC3/SLC25A4/FAS/CFLAR/BIRC2/NOL3/ARHGEF2/IRF3/PELI1/TSPO/CYLD	12
BP	GO:1901862	negative regulation of muscle tissue development	12/2619	62/18670	0.1521	0.3436	0.2577	JARID2/IGFBP5/RBP4/BMP4/LEF1/RGS4/MAPK11/CTDP1/TBX5/LUC7L/FZD7/TWIST1	12
BP	GO:1902305	regulation of sodium ion transmembrane transport	12/2619	62/18670	0.1521	0.3436	0.2577	SCN1B/ATP1B1/SNTA1/FXYD1/FXYD6/NETO2/KLHL24/ANK3/YWHAH/RANGRF/ATP2B4/NEDD4L	12
BP	GO:0009261	ribonucleotide catabolic process	7/2619	32/18670	0.1521	0.3436	0.2577	PDE1A/ENTPD4/NUDT9/NUDT11/ACAT1/NT5E/AMPD3	7
BP	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	7/2619	32/18670	0.1521	0.3436	0.2577	KIT/FGR/PDGFB/CD19/CCR7/NOD2/PTK2B	7
BP	GO:0046039	GTP metabolic process	7/2619	32/18670	0.1521	0.3436	0.2577	NME4/NME7/IMPDH2/NME5/MOCS2/NME3/AMPD3	7
BP	GO:0051085	chaperone cofactor-dependent protein refolding	7/2619	32/18670	0.1521	0.3436	0.2577	GAK/HSPH1/DNAJB14/HSPA6/BAG1/HSPA2/HSPA5	7
BP	GO:0060325	face morphogenesis	7/2619	32/18670	0.1521	0.3436	0.2577	CRISPLD2/NIPBL/LEF1/ASPH/PLEKHA1/EP300/SGPL1	7
BP	GO:1903955	positive regulation of protein targeting to mitochondrion	7/2619	32/18670	0.1521	0.3436	0.2577	FBXW7/MICALL2/PINK1/RAC2/ATG13/PRKAA1/UBL5	7
BP	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	11/2619	56/18670	0.1537	0.3436	0.2577	CRADD/CHEK2/ATM/PLK2/CCNB1/PML/GTSE1/CDK1/CDKN1A/EP300/RBL2	11
BP	GO:0046148	pigment biosynthetic process	11/2619	56/18670	0.1537	0.3436	0.2577	FECH/SLC7A11/ADA/IREB2/UROD/UROS/TSPO/NFE2L1/DCT/CPOX/PRPS1	11
BP	GO:0060113	inner ear receptor cell differentiation	11/2619	56/18670	0.1537	0.3436	0.2577	NOTCH1/ATP8B1/BMP4/FGF20/NAGLU/MCOLN3/RBPJ/SOD1/JAG2/SLC4A7/FZD2	11
BP	GO:0065002	intracellular protein transmembrane transport	11/2619	56/18670	0.1537	0.3436	0.2577	PEX10/NDUFA13/RTN2/TIMM10/PEX7/PEX2/SEC61A2/PEX12/PEX14/SRP54/HSPA5	11
BP	GO:0086002	cardiac muscle cell action potential involved in contraction	11/2619	56/18670	0.1537	0.3436	0.2577	SCN1B/SNTA1/KCNQ1/BIN1/KCNJ2/CACNB2/KCNJ8/KCNN2/CACNA1D/FLNA/NEDD4L	11
BP	GO:0120192	tight junction assembly	11/2619	56/18670	0.1537	0.3436	0.2577	ECT2/MICALL2/ARL2/PRKCH/PECAM1/WNT11/ROCK1/PRKCI/RAB13/MTDH/LSR	11
BP	GO:1902017	regulation of cilium assembly	11/2619	56/18670	0.1537	0.3436	0.2577	CEP135/SYNE2/MNS1/BBS4/RABEP2/IFT140/ARHGAP35/CYLD/VDAC3/CDKL5/DYNC2LI1	11
BP	GO:1903078	positive regulation of protein localization to plasma membrane	11/2619	56/18670	0.1537	0.3436	0.2577	TREM2/EGFR/PRNP/PRKCH/GPER1/IFNG/PRKCI/RANGRF/CIB1/LGALS3/SORBS1	11
BP	GO:0001892	embryonic placenta development	16/2619	87/18670	0.1537	0.3436	0.2577	CEBPA/EGFR/MDFI/LEF1/MED1/CDKN1C/RBPJ/PDGFB/PRDM1/TMED2/PLCD1/HIF1A/SETD2/BPTF/GGNBP2/CEBPB	16
BP	GO:0009308	amine metabolic process	24/2619	138/18670	0.154	0.3436	0.2577	ALDH7A1/HAAO/SNCA/SLC7A11/PSMB9/IDO1/COMT/NQO1/AGMAT/SMS/PSMC2/MOXD1/GDE1/PSMB6/HDC/PSMC3/SULT1A2/PSMD8/PSMB5/SRM/PSMD10/ATP2B4/HNMT/OAZ3	24
BP	GO:0006778	porphyrin-containing compound metabolic process	8/2619	38/18670	0.1545	0.3436	0.2577	FECH/BDH2/IREB2/UROD/UROS/TSPO/NFE2L1/CPOX	8
BP	GO:0009225	nucleotide-sugar metabolic process	8/2619	38/18670	0.1545	0.3436	0.2577	GNPDA1/MPI/DPAGT1/EXTL2/GMDS/GUK1/FUT8/PMM1	8
BP	GO:0032350	regulation of hormone metabolic process	8/2619	38/18670	0.1545	0.3436	0.2577	NFKB1/IFNG/EGR1/AKR1C3/HIF1A/GAL/TCF7L2/STC2	8
BP	GO:0060045	positive regulation of cardiac muscle cell proliferation	8/2619	38/18670	0.1545	0.3436	0.2577	NOTCH1/PIM1/ZFPM2/TBX5/CCNB1/RBPJ/CDK1/ERBB4	8
BP	GO:0010171	body morphogenesis	10/2619	50/18670	0.1548	0.3436	0.2577	MAB21L2/CRISPLD2/NIPBL/ZNF281/LEF1/ASPH/PLEKHA1/CLASP1/EP300/SGPL1	10
BP	GO:0034656	nucleobase-containing small molecule catabolic process	10/2619	50/18670	0.1548	0.3436	0.2577	ENTPD4/ADA/APOBEC3C/DPYS/TYMP/NUDT9/PNP/APOBEC3B/AHCY/NT5E	10
BP	GO:0043489	RNA stabilization	10/2619	50/18670	0.1548	0.3436	0.2577	CIRBP/HNRNPA0/SLC11A1/MAPKAPK2/DND1/YBX1/TARDBP/MYD88/HNRNPD/DAZL	10
BP	GO:0046854	phosphatidylinositol phosphorylation	10/2619	50/18670	0.1548	0.3436	0.2577	SOCS6/PIKFYVE/SOCS1/PIK3C2B/PIK3CB/EFR3A/PIK3CD/PIK3C2G/CISH/PIK3CA	10
BP	GO:1903793	positive regulation of anion transport	10/2619	50/18670	0.1548	0.3436	0.2577	TNFRSF11A/APOE/AGT/ATP8A1/P2RX4/PLA2R1/ABCB1/FABP3/CEBPB/ATF4	10
BP	GO:0003197	endocardial cushion development	9/2619	44/18670	0.1552	0.3436	0.2577	NOTCH1/SOX9/TMEM100/BMP4/FOXF1/NOS3/TBX5/RBPJ/TWIST1	9
BP	GO:0038084	vascular endothelial growth factor signaling pathway	9/2619	44/18670	0.1552	0.3436	0.2577	PRKD2/PGF/FOXC1/HSPB1/CD63/KDR/VEGFA/ADAMTS3/VEGFB	9
BP	GO:0045601	regulation of endothelial cell differentiation	9/2619	44/18670	0.1552	0.3436	0.2577	NOTCH1/APOLD1/TMEM100/NOTCH4/BMP4/ROCK1/CDH5/VEGFA/FOXJ2	9
BP	GO:0046688	response to copper ion	9/2619	44/18670	0.1552	0.3436	0.2577	SNCA/S100A13/PRNP/SORD/DAXX/NFE2L1/SOD1/AQP2/CDK1	9
BP	GO:0060412	ventricular septum morphogenesis	9/2619	44/18670	0.1552	0.3436	0.2577	NOTCH1/BMP4/WNT11/RBM15/ZFPM2/NOS3/RBPJ/ID2/FZD2	9
BP	GO:1901028	regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	9/2619	44/18670	0.1552	0.3436	0.2577	BAD/GSK3B/GZMB/TMEM14A/PPP1R13B/YWHAH/TP53BP2/ACAA2/HIP1R	9
BP	GO:1903573	negative regulation of response to endoplasmic reticulum stress	9/2619	44/18670	0.1552	0.3436	0.2577	CLU/HERPUD1/UBE2J1/NCK2/CREB3/DNAJC3/XBP1/HSPA5/USP14	9
BP	GO:0000338	protein deneddylation	3/2619	10/18670	0.1552	0.3436	0.2577	COPS6/COPS7A/COPS8	3
BP	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	3/2619	10/18670	0.1552	0.3436	0.2577	ITGAL/CD81/LGALS3	3
BP	GO:0003149	membranous septum morphogenesis	3/2619	10/18670	0.1552	0.3436	0.2577	BMP4/ID2/FZD2	3
BP	GO:0003211	cardiac ventricle formation	3/2619	10/18670	0.1552	0.3436	0.2577	NOTCH1/SMARCD3/TBX5	3
BP	GO:0006002	fructose 6-phosphate metabolic process	3/2619	10/18670	0.1552	0.3436	0.2577	MPI/PFKM/NFE2L1	3
BP	GO:0006560	proline metabolic process	3/2619	10/18670	0.1552	0.3436	0.2577	OAT/PYCR1/ALDH18A1	3
BP	GO:0007135	meiosis II	3/2619	10/18670	0.1552	0.3436	0.2577	BUB1B/RAD51C/DAZL	3
BP	GO:0007440	foregut morphogenesis	3/2619	10/18670	0.1552	0.3436	0.2577	NOTCH1/SMAD3/FOXF1	3
BP	GO:0008343	adult feeding behavior	3/2619	10/18670	0.1552	0.3436	0.2577	USP46/GHSR/AGRP	3
BP	GO:0010749	regulation of nitric oxide mediated signal transduction	3/2619	10/18670	0.1552	0.3436	0.2577	EGFR/VEGFA/ATP2B4	3
BP	GO:0010944	negative regulation of transcription by competitive promoter binding	3/2619	10/18670	0.1552	0.3436	0.2577	KDM2A/PHB/CREB1	3
BP	GO:0016102	diterpenoid biosynthetic process	3/2619	10/18670	0.1552	0.3436	0.2577	DHRS9/AKR1C3/ALDH1A3	3
BP	GO:0021694	cerebellar Purkinje cell layer formation	3/2619	10/18670	0.1552	0.3436	0.2577	RORA/AGTPBP1/HERC1	3
BP	GO:0021924	cell proliferation in external granule layer	3/2619	10/18670	0.1552	0.3436	0.2577	RORA/EGF/PSMG1	3
BP	GO:0021930	cerebellar granule cell precursor proliferation	3/2619	10/18670	0.1552	0.3436	0.2577	RORA/EGF/PSMG1	3
BP	GO:0030388	fructose 1,6-bisphosphate metabolic process	3/2619	10/18670	0.1552	0.3436	0.2577	PFKM/IFNG/ALDOC	3
BP	GO:0032070	regulation of deoxyribonuclease activity	3/2619	10/18670	0.1552	0.3436	0.2577	DDX11/GZMA/HMGB1	3
BP	GO:0032875	regulation of DNA endoreduplication	3/2619	10/18670	0.1552	0.3436	0.2577	FBXW7/SMC1A/FBXO5	3
BP	GO:0034058	endosomal vesicle fusion	3/2619	10/18670	0.1552	0.3436	0.2577	SPHK1/SAMD9/VPS8	3
BP	GO:0034085	establishment of sister chromatid cohesion	3/2619	10/18670	0.1552	0.3436	0.2577	NIPBL/DDX11/NAA50	3
BP	GO:0034447	very-low-density lipoprotein particle clearance	3/2619	10/18670	0.1552	0.3436	0.2577	LRPAP1/APOE/APOC1	3
BP	GO:0039530	MDA-5 signaling pathway	3/2619	10/18670	0.1552	0.3436	0.2577	IRF3/DDX60/RIOK3	3
BP	GO:0044803	multi-organism membrane organization	3/2619	10/18670	0.1552	0.3436	0.2577	FCHSD2/CCR5/CXCR4	3
BP	GO:0045348	positive regulation of MHC class II biosynthetic process	3/2619	10/18670	0.1552	0.3436	0.2577	JAK2/IFNG/XBP1	3
BP	GO:0045625	regulation of T-helper 1 cell differentiation	3/2619	10/18670	0.1552	0.3436	0.2577	RIPK2/IL4R/TNFSF4	3
BP	GO:0045945	positive regulation of transcription by RNA polymerase III	3/2619	10/18670	0.1552	0.3436	0.2577	CEBPA/AR/CHD8	3
BP	GO:0046485	ether lipid metabolic process	3/2619	10/18670	0.1552	0.3436	0.2577	DHRS7B/PEX7/AGPS	3
BP	GO:0046498	S-adenosylhomocysteine metabolic process	3/2619	10/18670	0.1552	0.3436	0.2577	GAMT/PEMT/AHCY	3
BP	GO:0046532	regulation of photoreceptor cell differentiation	3/2619	10/18670	0.1552	0.3436	0.2577	NOTCH1/DIO3/SOX9	3
BP	GO:0046710	GDP metabolic process	3/2619	10/18670	0.1552	0.3436	0.2577	GUK1/MPP1/TJP2	3
BP	GO:0048304	positive regulation of isotype switching to IgG isotypes	3/2619	10/18670	0.1552	0.3436	0.2577	PTPRC/CD28/CD40	3
BP	GO:0050861	positive regulation of B cell receptor signaling pathway	3/2619	10/18670	0.1552	0.3436	0.2577	PRKCB/PRKCH/CD81	3
BP	GO:0051255	spindle midzone assembly	3/2619	10/18670	0.1552	0.3436	0.2577	RACGAP1/KIF4A/AURKB	3
BP	GO:0051593	response to folic acid	3/2619	10/18670	0.1552	0.3436	0.2577	FOLR1/FOLR2/TYMS	3
BP	GO:0051901	positive regulation of mitochondrial depolarization	3/2619	10/18670	0.1552	0.3436	0.2577	TSPO/KDR/MYOC	3
BP	GO:0052646	alditol phosphate metabolic process	3/2619	10/18670	0.1552	0.3436	0.2577	ABHD6/GK/ACP6	3
BP	GO:0060600	dichotomous subdivision of an epithelial terminal unit	3/2619	10/18670	0.1552	0.3436	0.2577	SEMA3A/PLXND1/PLXNA1	3
BP	GO:0060768	regulation of epithelial cell proliferation involved in prostate gland development	3/2619	10/18670	0.1552	0.3436	0.2577	NOTCH1/AR/SERPINF1	3
BP	GO:0061983	meiosis II cell cycle process	3/2619	10/18670	0.1552	0.3436	0.2577	BUB1B/RAD51C/DAZL	3
BP	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain	3/2619	10/18670	0.1552	0.3436	0.2577	CCNK/GTF2H3/CDK9	3
BP	GO:0071233	cellular response to leucine	3/2619	10/18670	0.1552	0.3436	0.2577	UBR2/RRAGD/SESN1	3
BP	GO:0071838	cell proliferation in bone marrow	3/2619	10/18670	0.1552	0.3436	0.2577	LEF1/MAP3K3/HMGA2	3
BP	GO:0071863	regulation of cell proliferation in bone marrow	3/2619	10/18670	0.1552	0.3436	0.2577	LEF1/MAP3K3/HMGA2	3
BP	GO:0072015	glomerular visceral epithelial cell development	3/2619	10/18670	0.1552	0.3436	0.2577	BMP4/MAGI2/PODXL	3
BP	GO:0072203	cell proliferation involved in metanephros development	3/2619	10/18670	0.1552	0.3436	0.2577	STAT1/MYC/EGR1	3
BP	GO:0072610	interleukin-12 secretion	3/2619	10/18670	0.1552	0.3436	0.2577	MAPK11/CCR7/TLR8	3
BP	GO:0072641	type I interferon secretion	3/2619	10/18670	0.1552	0.3436	0.2577	CHUK/MMP12/HMGB1	3
BP	GO:0090037	positive regulation of protein kinase C signaling	3/2619	10/18670	0.1552	0.3436	0.2577	WNT11/CD40/VEGFA	3
BP	GO:0098722	asymmetric stem cell division	3/2619	10/18670	0.1552	0.3436	0.2577	FGF13/ING2/ARHGEF2	3
BP	GO:0110096	cellular response to aldehyde	3/2619	10/18670	0.1552	0.3436	0.2577	AKR1B1/AKR1B10/ESD	3
BP	GO:1901526	positive regulation of mitophagy	3/2619	10/18670	0.1552	0.3436	0.2577	VPS13C/PINK1/OPTN	3
BP	GO:1902237	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	3/2619	10/18670	0.1552	0.3436	0.2577	NCK2/PTPN2/DDIT3	3
BP	GO:1902915	negative regulation of protein polyubiquitination	3/2619	10/18670	0.1552	0.3436	0.2577	DYSF/TRIP12/UBR5	3
BP	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway	3/2619	10/18670	0.1552	0.3436	0.2577	ADAM17/CASP4/TRIM32	3
BP	GO:1903789	regulation of amino acid transmembrane transport	3/2619	10/18670	0.1552	0.3436	0.2577	RGS4/AGT/ARL6IP5	3
BP	GO:1903897	regulation of PERK-mediated unfolded protein response	3/2619	10/18670	0.1552	0.3436	0.2577	NCK2/PTPN2/HSPA5	3
BP	GO:2000665	regulation of interleukin-13 secretion	3/2619	10/18670	0.1552	0.3436	0.2577	TNFRSF21/IL17RB/IL17RA	3
BP	GO:2000849	regulation of glucocorticoid secretion	3/2619	10/18670	0.1552	0.3436	0.2577	TAC1/GAL/CRY1	3
BP	GO:2001054	negative regulation of mesenchymal cell apoptotic process	3/2619	10/18670	0.1552	0.3436	0.2577	SOX9/GDF5/HIF1A	3
BP	GO:2001225	regulation of chloride transport	3/2619	10/18670	0.1552	0.3436	0.2577	PRNP/CA2/ABCB1	3
BP	GO:0006959	humoral immune response	57/2619	356/18670	0.156	0.3453	0.259	CXCL9/CXCL10/NOTCH1/C7/SCARA3/TREM2/CXCL13/PROS1/CLU/CXCL11/SLPI/SUSD4/PTPRC/GPR183/TNFRSF21/CD83/CFD/HLA-E/CXCL2/IGLV1-44/IGHM/CD28/CFI/PHB/FAM3A/ELANE/CD81/TRBC1/CR1/IFNG/GNLY/IL6/RBPJ/SLC11A1/DEFA6/CD19/HLA-DQB1/HMGN2/CCR7/C4BPB/CXCL3/IGLL5/CCL13/IGLC1/MBL2/CTSG/DEFA5/FCN1/S100A12/KRT1/MS4A1/CXCL8/CCR2/DEFB126/REG3A/CFP/CD59	57
BP	GO:0007163	establishment or maintenance of cell polarity	35/2619	210/18670	0.1567	0.3466	0.2599	UST/NDE1/FGF13/MAP7/ACTR3/GSK3B/RHOF/WNT11/FAT1/ARHGEF2/ROCK1/NDC80/FOXF1/NEK3/KRIT1/CDH5/LIN7B/PRKCI/RND2/CLASP1/SIPA1L3/LLGL2/ARHGAP35/CCR7/FERMT1/AMOTL2/PARVB/RHOH/WEE1/GOLPH3/CD3G/PTK2B/RAP1B/ARFGEF1/ACTR2	35
BP	GO:0031145	anaphase-promoting complex-dependent catabolic process	15/2619	81/18670	0.1568	0.3466	0.2599	PSMB9/PTTG1/BUB1B/PSMC2/PSMB6/CCNB1/PSMC3/CDC20/AURKB/PSMD8/UBB/PSMB5/PSMD10/CDK1/FBXO5	15
BP	GO:0034109	homotypic cell-cell adhesion	15/2619	81/18670	0.1568	0.3466	0.2599	CCL5/SLC7A11/METAP1/FIBP/ANK3/HSPB1/PIK3CB/COMP/PRKCQ/HBB/TYRO3/CXADR/SH2B3/FLNA/TSPAN32	15
BP	GO:0048708	astrocyte differentiation	15/2619	81/18670	0.1568	0.3466	0.2599	NOTCH1/TREM2/SOX9/LAMC3/MAPK3/EGFR/BIN1/ID4/IFNG/IL6/EPHA4/ID2/KRAS/PLP1/SMO	15
BP	GO:0035282	segmentation	18/2619	100/18670	0.1577	0.3484	0.2613	MTF2/SFRP1/NOTCH1/SMAD3/FOXC1/MEOX1/SEMA3A/NLE1/ATM/BMP4/LEF1/FOXF1/POFUT1/SEMA3F/RBPJ/TMED2/ABI1/EP300	18
BP	GO:0032956	regulation of actin cytoskeleton organization	55/2619	343/18670	0.1581	0.3492	0.2619	SFRP1/IQGAP2/ACTR3B/ECT2/ARPC1A/SMAD3/TMOD1/CDC42EP3/FCHSD2/PFN2/BAIAP2/NCK2/ACTR3/CORO2B/LIMCH1/NTF3/CAPZA1/BIN1/EFNA5/RHOF/WNT11/ROCK1/BBS4/PTGER4/S1PR1/RGS4/PPM1E/TAOK1/TMOD2/RND2/CLASP1/FHOD3/MAGEL2/MYOC/SCIN/ARHGAP35/CCR7/AP1AR/SEMA3E/MLST8/TMSB10/ALMS1/ARPC5L/NF2/TAC1/CTTN/AKAP13/RHOH/HIP1R/CYFIP1/LIMA1/FLNA/PTK2B/ARFGEF1/ACTR2	55
BP	GO:0001707	mesoderm formation	14/2619	75/18670	0.1598	0.3526	0.2644	HOXA11/EYA2/SMAD3/FOXC1/EXT2/BMP4/WNT11/LEF1/FOXF1/WLS/SIX2/TLX2/NF2/HMGA2	14
BP	GO:0010611	regulation of cardiac muscle hypertrophy	14/2619	75/18670	0.1598	0.3526	0.2644	NOTCH1/JARID2/TNFRSF1B/SMAD3/ROCK1/RGS4/AGT/CTDP1/IGF1/PIN1/P2RX4/PPP3CA/ATP2B4/CDK9	14
BP	GO:0015914	phospholipid transport	14/2619	75/18670	0.1598	0.3526	0.2644	ATP8B1/APOE/PITPNC1/OSBPL8/TMEM30A/PCTP/APOC1/ABCC1/SCP2/ATP8A1/ATP11B/ABCB1/ATP10A/STARD7	14
BP	GO:0000966	RNA 5'-end processing	5/2619	21/18670	0.1617	0.3544	0.2658	HSD17B10/POP7/PIWIL2/RPP14/USP14	5
BP	GO:0003177	pulmonary valve development	5/2619	21/18670	0.1617	0.3544	0.2658	NOTCH1/TNFRSF1B/BMP4/NOS3/RBPJ	5
BP	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen	5/2619	21/18670	0.1617	0.3544	0.2658	NDUFA4/COX6C/COX8A/COX6A1/COX5B	5
BP	GO:0010829	negative regulation of glucose transmembrane transport	5/2619	21/18670	0.1617	0.3544	0.2658	ENPP1/PRKCB/PID1/PEA15/GRB10	5
BP	GO:0019646	aerobic electron transport chain	5/2619	21/18670	0.1617	0.3544	0.2658	NDUFA4/COX6C/COX8A/COX6A1/COX5B	5
BP	GO:0030728	ovulation	5/2619	21/18670	0.1617	0.3544	0.2658	IL4R/HPGD/NOS3/EREG/INHBB	5
BP	GO:0035455	response to interferon-alpha	5/2619	21/18670	0.1617	0.3544	0.2658	ADAR/LAMP3/TPR/AXL/IFITM2	5
BP	GO:0046132	pyrimidine ribonucleoside biosynthetic process	5/2619	21/18670	0.1617	0.3544	0.2658	NME4/NME7/NME5/NME3/CTPS1	5
BP	GO:0046716	muscle cell cellular homeostasis	5/2619	21/18670	0.1617	0.3544	0.2658	PFKM/SOD1/HIF1A/GAA/TRIM32	5
BP	GO:0046827	positive regulation of protein export from nucleus	5/2619	21/18670	0.1617	0.3544	0.2658	GSK3B/TPR/CAMK1/GTSE1/TCF7L2	5
BP	GO:0048485	sympathetic nervous system development	5/2619	21/18670	0.1617	0.3544	0.2658	SEMA3A/FZD3/NTRK1/SEMA3F/INSM1	5
BP	GO:0070584	mitochondrion morphogenesis	5/2619	21/18670	0.1617	0.3544	0.2658	FIS1/PID1/POLDIP2/NUBPL/NDUFS6	5
BP	GO:0070734	histone H3-K27 methylation	5/2619	21/18670	0.1617	0.3544	0.2658	MTF2/SUZ12/EZH2/EED/OGT	5
BP	GO:0071498	cellular response to fluid shear stress	5/2619	21/18670	0.1617	0.3544	0.2658	MAPK7/ASS1/CA2/HAS2/PTK2B	5
BP	GO:0072010	glomerular epithelium development	5/2619	21/18670	0.1617	0.3544	0.2658	FOXC1/PECAM1/BMP4/MAGI2/PODXL	5
BP	GO:0090280	positive regulation of calcium ion import	5/2619	21/18670	0.1617	0.3544	0.2658	STC1/PDGFB/CALCR/TRPV2/LGALS3	5
BP	GO:1900273	positive regulation of long-term synaptic potentiation	5/2619	21/18670	0.1617	0.3544	0.2658	LGMN/ADCY1/NRGN/CREB1/STAU1	5
BP	GO:1901739	regulation of myoblast fusion	5/2619	21/18670	0.1617	0.3544	0.2658	CXCL9/CXCL10/IL4R/CFLAR/TNFSF14	5
BP	GO:1902884	positive regulation of response to oxidative stress	5/2619	21/18670	0.1617	0.3544	0.2658	FBXW7/ACOX2/SFPQ/MCL1/SOD1	5
BP	GO:0022618	ribonucleoprotein complex assembly	45/2619	277/18670	0.1623	0.3557	0.2668	SRPK1/SETX/ADAR/CIRBP/CELF2/ATR/LSM4/NLE1/ATM/SF3B1/PUM2/PRMT5/SART3/LSM3/NOL3/CELF1/RPL12/CPSF7/MRPL11/DDX23/MDN1/SNUPN/SFSWAP/PTBP2/EIF2S3/EIF3A/DYNC1H1/RPS5/RUVBL2/SCAF11/EIF3I/DDX1/EIF2D/SNRPD2/AGO3/PRKAA1/TXNL4A/YTHDC1/MRPS11/LUC7L/MRPL20/EIF6/STYXL1/GEMIN2/RPLP0	45
BP	GO:0086003	cardiac muscle cell contraction	13/2619	69/18670	0.1627	0.3563	0.2672	SCN1B/SNTA1/SRI/KCNQ1/STC1/BIN1/KCNJ2/CACNB2/KCNJ8/KCNN2/CACNA1D/FLNA/NEDD4L	13
BP	GO:0006720	isoprenoid metabolic process	24/2619	139/18670	0.1628	0.3563	0.2672	AKR1B1/PNPLA4/AKR1B10/GPC5/PMVK/APOM/ALDH1A1/DHRS3/DHRS9/SDC1/RBP4/EGFR/APOE/PHYH/DPAGT1/AKR1C3/ALDH3A2/DHDDS/ALDH1A3/LPL/COQ2/AKR1C4/TH/MVK	24
BP	GO:0051588	regulation of neurotransmitter transport	24/2619	139/18670	0.1628	0.3563	0.2672	TACR2/SNCA/RIMS3/PREPL/PRKCB/SYT11/PFN2/MCTP1/GSK3B/HRH3/GPER1/RGS4/CHRNA3/SNCAIP/HCRT/VAMP7/ADCY1/ARL6IP5/CACNB2/CACNA1D/SYT1/SYN1/RAP1B/NAPA	24
BP	GO:0051028	mRNA transport	26/2619	152/18670	0.1631	0.3568	0.2676	CETN2/HNRNPA2B1/NXF3/NUP160/IGF2BP3/THOC2/NUP153/DDX39A/THOC1/TPR/NUP50/SEC13/RANBP2/NXF1/KIF5C/SRSF4/NUP210/HNRNPA1/NUP43/NDC1/SETD2/YTHDC1/NCBP2/MVP/NUP98/NUP62	26
BP	GO:0022404	molting cycle process	16/2619	88/18670	0.1649	0.3602	0.2702	NOTCH1/SOX9/IGFBP5/SOS1/EGFR/FZD3/LAMA5/RBPJ/DKK4/LGR5/FERMT1/ERCC2/HDAC1/GAL/FZD6/SMO	16
BP	GO:0022405	hair cycle process	16/2619	88/18670	0.1649	0.3602	0.2702	NOTCH1/SOX9/IGFBP5/SOS1/EGFR/FZD3/LAMA5/RBPJ/DKK4/LGR5/FERMT1/ERCC2/HDAC1/GAL/FZD6/SMO	16
BP	GO:0043506	regulation of JUN kinase activity	16/2619	88/18670	0.1649	0.3602	0.2702	SFRP1/MAP3K5/RIPK2/TNIK/MAP3K11/TNFRSF11A/BIRC7/DNAJA1/PTPN22/MAP4K1/DAXX/TAOK1/EPHA4/TAOK3/PTK2B/CD40LG	16
BP	GO:0098773	skin epidermis development	16/2619	88/18670	0.1649	0.3602	0.2702	NOTCH1/SOX9/IGFBP5/SOS1/EGFR/FZD3/LAMA5/RBPJ/DKK4/LGR5/FERMT1/ERCC2/HDAC1/GAL/FZD6/SMO	16
BP	GO:0046890	regulation of lipid biosynthetic process	33/2619	198/18670	0.165	0.3604	0.2703	SIK1/SPHK1/FBXW7/PMVK/ABHD6/ERLIN2/APOE/CDK4/HTR2B/ASAH1/GPER1/FAM3A/SC5D/NFKB1/IFNG/APOC1/WDTC1/MBTPS1/TSPO/NR1H2/EGR1/AKR1C3/PDGFB/DHCR7/KPNB1/SOD1/PRKAA1/CREB1/EIF6/FABP3/NFYC/MVK/SORBS1	33
BP	GO:0031571	mitotic G1 DNA damage checkpoint	12/2619	63/18670	0.1654	0.361	0.2707	RFWD3/CRADD/CHEK2/ATM/PLK2/CCNB1/PML/GTSE1/CDK1/CDKN1A/EP300/RBL2	12
BP	GO:0044819	mitotic G1/S transition checkpoint	12/2619	63/18670	0.1654	0.361	0.2707	RFWD3/CRADD/CHEK2/ATM/PLK2/CCNB1/PML/GTSE1/CDK1/CDKN1A/EP300/RBL2	12
BP	GO:1903052	positive regulation of proteolysis involved in cellular protein catabolic process	21/2619	120/18670	0.166	0.3621	0.2716	NUPR1/CEBPA/TREM2/FBXW7/CLU/HERPUD1/CBFA2T3/EGF/GSK3B/CHFR/PSMC2/PLK2/TRIB1/DET1/CSNK1A1/RNF19B/CSNK1E/EDEM1/PSMD10/RNF14/PTK2B	21
BP	GO:0007369	gastrulation	31/2619	185/18670	0.166	0.3621	0.2716	HOXA11/SFRP1/EYA2/SMAD3/FOXC1/ITGA5/EXT2/MAPK7/BMP4/WNT11/LEF1/SUPT20H/ARID1A/FOXF1/WLS/DLD/LRP5/SIX2/CLASP1/HSBP1/TLX2/TGIF2/SETD2/IL1RN/NF2/ITGB5/ETS2/COL4A2/FZD7/HMGA2/TENM4	31
BP	GO:0010632	regulation of epithelial cell migration	47/2619	291/18670	0.1665	0.3631	0.2723	PTN/NOTCH1/LGMN/SOX9/PRKD2/FBXW7/CXCL13/ANGPT1/MACF1/SEMA4A/SEMA3A/ADAM17/PFN2/STC1/ANGPT2/APOE/AAMP/BMP4/CSNK2B/PPARG/CD40/HSPB1/KRIT1/IFNG/PLK2/AGT/NOS3/FGF18/KDR/MAP4K4/HBEGF/CLASP1/PDGFB/VEGFA/P2RX4/HMGB1/MAP3K3/HIF1A/EMP2/HAS2/TAC1/CIB1/STAT5A/MAPRE2/PTK2B/SERPINF1/ARSB	47
BP	GO:0016064	immunoglobulin mediated immune response	36/2619	218/18670	0.1667	0.3634	0.2725	C7/PARP3/TFRC/IL27RA/ERCC1/CLU/NBN/SUSD4/IL4R/PTPRC/THOC1/HLA-E/IGLV1-44/IGHM/CD28/CFI/CD40/GCNT3/TCIRG1/CD81/TRBC1/CR1/CD27/XCL1/CD19/HLA-DQB1/TNFSF4/C4BPB/BATF/IGLL5/IGLC1/MBL2/BCL10/IL13RA2/TLR8/CD40LG	36
BP	GO:0007224	smoothened signaling pathway	23/2619	133/18670	0.167	0.3638	0.2729	ZIC1/SFRP1/TCTN1/GAS1/ENPP1/IFT46/TMEM231/ARL3/RORA/TCTN3/IFT52/DYRK2/BMP4/C2CD3/B9D1/FKBP8/FOXF1/CD3E/IFT140/PKD2L1/WDR11/SMO/TCTN2	23
BP	GO:0045834	positive regulation of lipid metabolic process	25/2619	146/18670	0.1673	0.3645	0.2734	ABHD6/APOE/KIT/HTR2B/PPARG/FGR/TAZ/CD81/IFNG/APOC1/DGKZ/AGT/NR1H2/GHSR/PDGFB/CD19/CCR7/NOD2/PRKAA1/CREB1/FABP3/PTK2B/STOML2/TWIST1/SORBS1	25
BP	GO:0019320	hexose catabolic process	11/2619	57/18670	0.1678	0.3651	0.2738	ALDH1A1/BAD/PGM1/FUT1/ENO2/PFKM/LRP5/FUT8/ALDOC/FUT4/ADPGK	11
BP	GO:0072431	signal transduction involved in mitotic G1 DNA damage checkpoint	11/2619	57/18670	0.1678	0.3651	0.2738	CRADD/CHEK2/ATM/PLK2/CCNB1/PML/GTSE1/CDK1/CDKN1A/EP300/RBL2	11
BP	GO:1902400	intracellular signal transduction involved in G1 DNA damage checkpoint	11/2619	57/18670	0.1678	0.3651	0.2738	CRADD/CHEK2/ATM/PLK2/CCNB1/PML/GTSE1/CDK1/CDKN1A/EP300/RBL2	11
BP	GO:0002027	regulation of heart rate	18/2619	101/18670	0.1681	0.3651	0.2738	GCH1/SCN1B/SNTA1/SRI/KCNQ1/SEMA3A/ADA/BIN1/KCNJ2/RGS4/AGT/IRX5/CACNB2/AKAP9/RANGRF/TAC1/CACNA1D/SLC1A1	18
BP	GO:1903008	organelle disassembly	18/2619	101/18670	0.1681	0.3651	0.2738	FIS1/FBXW7/VPS13C/GABARAPL1/GABARAPL2/PINK1/ATG2B/TSPO/ATG13/OPTN/SPAST/HIF1A/EIF2D/CTTN/CDK1/ATG12/GABARAP/CLEC16A	18
BP	GO:0032201	telomere maintenance via semi-conservative replication	6/2619	27/18670	0.1682	0.3651	0.2738	POLD2/DNA2/RPA1/RPA3/POLD4/RFC2	6
BP	GO:0036475	neuron death in response to oxidative stress	6/2619	27/18670	0.1682	0.3651	0.2738	FBXW7/SLC7A11/PINK1/MCL1/HIF1A/ATF4	6
BP	GO:0046885	regulation of hormone biosynthetic process	6/2619	27/18670	0.1682	0.3651	0.2738	NFKB1/IFNG/EGR1/AKR1C3/HIF1A/STC2	6
BP	GO:0060143	positive regulation of syncytium formation by plasma membrane fusion	6/2619	27/18670	0.1682	0.3651	0.2738	CXCL9/TREM2/IL4R/TYROBP/CAMK1/TNFSF14	6
BP	GO:0071450	cellular response to oxygen radical	6/2619	27/18670	0.1682	0.3651	0.2738	GCH1/FBLN5/NQO1/NOS3/SOD1/PRDX2	6
BP	GO:0071451	cellular response to superoxide	6/2619	27/18670	0.1682	0.3651	0.2738	GCH1/FBLN5/NQO1/NOS3/SOD1/PRDX2	6
BP	GO:0006855	drug transmembrane transport	15/2619	82/18670	0.1685	0.3652	0.2739	FOLR1/SLC7A5/PRAF2/SLC7A11/ATP8B1/SLC25A1/SLC22A18/TMEM30A/FOLR2/RGS4/AGT/ABCC1/ARL6IP5/SLC15A2/SLC1A1	15
BP	GO:0034502	protein localization to chromosome	15/2619	82/18670	0.1685	0.3652	0.2739	PARP3/NIPBL/ATR/TNKS2/EZH2/RPA1/NDC80/MIS12/BRCA2/ATRX/AURKB/RUVBL2/NABP2/SETD2/CDK1	15
BP	GO:0071158	positive regulation of cell cycle arrest	15/2619	82/18670	0.1685	0.3652	0.2739	CRADD/CHEK2/ATM/PLK2/INSM1/CCNB1/CRLF3/PML/GTSE1/CDK1/ID2/CDKN1A/EP300/HMGA2/RBL2	15
BP	GO:0007566	embryo implantation	10/2619	51/18670	0.1699	0.3678	0.2759	BSG/STC1/RXRA/POLR1B/ARID1A/SOD1/EMP2/TIMP1/FBLN1/STC2	10
BP	GO:0045599	negative regulation of fat cell differentiation	10/2619	51/18670	0.1699	0.3678	0.2759	ENPP1/SMAD3/RORA/GPER1/ID4/ZFPM2/IL6/SORT1/ZFP36L2/DDIT3	10
BP	GO:0097366	response to bronchodilator	10/2619	51/18670	0.1699	0.3678	0.2759	SLC18A2/CCNA2/CFLAR/RANBP2/RGS4/CCR7/PPP3CA/SOD1/HNRNPD/TH	10
BP	GO:0006690	icosanoid metabolic process	20/2619	114/18670	0.1702	0.3682	0.2762	HPGDS/LTC4S/PTGS1/TBXAS1/MAPK3/ALOX5AP/EPHX2/CES2/MGST3/HPGD/GPX1/GPX4/PLA2G4C/ABCC1/AKR1C3/PTGDS/MAPKAPK2/ACOX1/CBR1/AKR1C4	20
BP	GO:0008543	fibroblast growth factor receptor signaling pathway	20/2619	114/18670	0.1702	0.3682	0.2762	SETX/PRKD2/MAPK3/POLR2J/POLR2I/POLR2L/POLR2E/POLR2F/FGF20/FIBP/SHOC2/POLR2C/TIA1/FGF18/SHCBP1/POLR2G/GALNT3/HNRNPA1/NCBP2/FGF5	20
BP	GO:0002717	positive regulation of natural killer cell mediated immunity	7/2619	33/18670	0.1712	0.3682	0.2762	RASGRP1/HLA-F/HLA-G/MICB/HLA-E/CRTAM/ULBP2	7
BP	GO:0010092	specification of animal organ identity	7/2619	33/18670	0.1712	0.3682	0.2762	SIX1/HOXA11/AR/SMARCD3/BMP4/RBPJ/HOXC11	7
BP	GO:0014072	response to isoquinoline alkaloid	7/2619	33/18670	0.1712	0.3682	0.2762	ADA/PENK/PEA15/CXCR4/RGS4/SRR/TAC1	7
BP	GO:0016486	peptide hormone processing	7/2619	33/18670	0.1712	0.3682	0.2762	CPA3/PCSK1/PCSK7/CMA1/CPE/CTSG/CORIN	7
BP	GO:0031112	positive regulation of microtubule polymerization or depolymerization	7/2619	33/18670	0.1712	0.3682	0.2762	STMN2/ARL2/DRG1/CLASP1/SPAST/KATNB1/AKAP9	7
BP	GO:0032691	negative regulation of interleukin-1 beta production	7/2619	33/18670	0.1712	0.3682	0.2762	TNFAIP3/TREM2/CX3CR1/CARD8/IGF1/GHSR/PML	7
BP	GO:0035115	embryonic forelimb morphogenesis	7/2619	33/18670	0.1712	0.3682	0.2762	HOXA11/NIPBL/OSR2/TBX5/EN1/HOXD9/TWIST1	7
BP	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	7/2619	33/18670	0.1712	0.3682	0.2762	SRI/MPC2/BAD/ARRB1/OXCT1/ANO1/HIF1A	7
BP	GO:0036314	response to sterol	7/2619	33/18670	0.1712	0.3682	0.2762	PMVK/RORA/GRAMD1C/CCR5/ABCA2/NFE2L1/SMO	7
BP	GO:0043278	response to morphine	7/2619	33/18670	0.1712	0.3682	0.2762	ADA/PENK/PEA15/CXCR4/RGS4/SRR/TAC1	7
BP	GO:0051194	positive regulation of cofactor metabolic process	7/2619	33/18670	0.1712	0.3682	0.2762	SNCA/INSR/PFKFB3/IFNG/IGF1/HIF1A/PRKAA1	7
BP	GO:0061036	positive regulation of cartilage development	7/2619	33/18670	0.1712	0.3682	0.2762	HOXA11/SOX9/SMAD3/BMP4/GDF5/FGF18/ZNF219	7
BP	GO:0071985	multivesicular body sorting pathway	7/2619	33/18670	0.1712	0.3682	0.2762	VPS37C/RAB27A/UVRAG/CHMP2A/TMEM50B/SORT1/CHMP1B	7
BP	GO:2000758	positive regulation of peptidyl-lysine acetylation	7/2619	33/18670	0.1712	0.3682	0.2762	MAPK3/NAP1L2/ARRB1/AUTS2/RUVBL2/PRKAA1/PIWIL2	7
BP	GO:0002244	hematopoietic progenitor cell differentiation	28/2619	166/18670	0.1712	0.3682	0.2762	SFRP1/NOTCH1/ADAR/MLF1/PTPRC/FOXC1/SOS1/MEOX1/PSMB9/AGPAT5/N4BP2L2/KIT/BMP4/PUS7/PSMC2/EML1/PSMB6/PSMC3/SIPA1L3/PSMD8/PSMB5/BATF/TOP2A/ACP6/ZBTB24/PSMD10/ERCC2/TCF3	28
BP	GO:0048538	thymus development	9/2619	45/18670	0.1713	0.3682	0.2762	SIX1/JARID2/MAPK3/ATM/BCL11B/CCNB2/SOD1/PRDX2/RAF1	9
BP	GO:0048701	embryonic cranial skeleton morphogenesis	9/2619	45/18670	0.1713	0.3682	0.2762	SIX1/NIPBL/SMAD3/BMP4/SIX2/IFT140/IRX5/SETD2/TWIST1	9
BP	GO:1903364	positive regulation of cellular protein catabolic process	24/2619	140/18670	0.1717	0.3682	0.2762	TNFAIP3/NUPR1/CEBPA/TREM2/FBXW7/CLU/HERPUD1/CBFA2T3/EGF/APOE/GSK3B/CHFR/PSMC2/CD81/PLK2/TRIB1/DET1/CSNK1A1/RNF19B/CSNK1E/EDEM1/PSMD10/RNF14/PTK2B	24
BP	GO:0007257	activation of JUN kinase activity	8/2619	39/18670	0.1719	0.3682	0.2762	MAP3K5/RIPK2/MAP3K11/BIRC7/MAP4K1/DAXX/TAOK1/CD40LG	8
BP	GO:0008207	C21-steroid hormone metabolic process	8/2619	39/18670	0.1719	0.3682	0.2762	AKR1B1/DHRS9/FDX1/CYP11A1/TSPO/EGR1/AKR1C3/AKR1C4	8
BP	GO:0030501	positive regulation of bone mineralization	8/2619	39/18670	0.1719	0.3682	0.2762	PTN/NELL1/SMAD3/ATRAID/BMP4/OSR2/ADRB2/ATP2B1	8
BP	GO:0031062	positive regulation of histone methylation	8/2619	39/18670	0.1719	0.3682	0.2762	MTF2/JARID2/WDR61/DNMT1/AUTS2/EED/PAXBP1/OGT	8
BP	GO:0033574	response to testosterone	8/2619	39/18670	0.1719	0.3682	0.2762	AR/CFLAR/BAD/CDK4/CSNK2B/TSPO/NASP/PSPH	8
BP	GO:0035886	vascular smooth muscle cell differentiation	8/2619	39/18670	0.1719	0.3682	0.2762	NOTCH1/DNMT1/SGCB/KIT/GPER1/COMP/PDGFB/VEGFA	8
BP	GO:0045684	positive regulation of epidermis development	8/2619	39/18670	0.1719	0.3682	0.2762	NOTCH1/FOXC1/NCOA3/PRKCH/KRT10/BMP4/MED1/GAL	8
BP	GO:0060306	regulation of membrane repolarization	8/2619	39/18670	0.1719	0.3682	0.2762	SCN1B/SNTA1/KCNQ1/KCNJ2/AKAP9/CACNA1D/FLNA/NEDD4L	8
BP	GO:0060969	negative regulation of gene silencing	8/2619	39/18670	0.1719	0.3682	0.2762	ADAR/ATAD2B/PPARG/DND1/PPP3CA/NCOR1/ATAD2/HMGA1	8
BP	GO:0072529	pyrimidine-containing compound catabolic process	8/2619	39/18670	0.1719	0.3682	0.2762	ENTPD4/TDG/APOBEC3C/DPYS/TYMP/APOBEC3B/NT5E/ALDH6A1	8
BP	GO:1902116	negative regulation of organelle assembly	8/2619	39/18670	0.1719	0.3682	0.2762	NUPR1/MDM1/PINK1/SEC22B/ARHGEF2/CHMP2A/KAT2B/STYXL1	8
BP	GO:1902229	regulation of intrinsic apoptotic signaling pathway in response to DNA damage	8/2619	39/18670	0.1719	0.3682	0.2762	CLU/ING2/HNRNPK/USP47/CD44/TAF9B/RAD9A/TRIM32	8
BP	GO:0048844	artery morphogenesis	14/2619	76/18670	0.1721	0.3684	0.2763	SIX1/NOTCH1/FOLR1/FOXC1/APOE/BMP4/WNT11/HPGD/FOXF1/COMP/RBPJ/PRDM1/VEGFA/COL3A1	14
BP	GO:0050810	regulation of steroid biosynthetic process	17/2619	95/18670	0.1722	0.3684	0.2763	PMVK/ERLIN2/APOE/ASAH1/SC5D/NFKB1/IFNG/MBTPS1/TSPO/EGR1/AKR1C3/DHCR7/KPNB1/SOD1/PRKAA1/NFYC/MVK	17
BP	GO:1903076	regulation of protein localization to plasma membrane	17/2619	95/18670	0.1722	0.3684	0.2763	GBP1/TREM2/AR/PID1/EGFR/PRNP/PRKCH/AP2M1/VTI1B/GPER1/IFNG/PRKCI/TMEM59/RANGRF/CIB1/LGALS3/SORBS1	17
BP	GO:2000060	positive regulation of ubiquitin-dependent protein catabolic process	17/2619	95/18670	0.1722	0.3684	0.2763	CEBPA/FBXW7/CLU/HERPUD1/CBFA2T3/EGF/GSK3B/CHFR/PLK2/TRIB1/DET1/CSNK1A1/RNF19B/CSNK1E/PSMD10/RNF14/PTK2B	17
BP	GO:1904659	glucose transmembrane transport	19/2619	108/18670	0.1745	0.3732	0.2799	SLC2A3/ENPP1/PRKCB/PID1/RTN2/INSR/OSBPL8/PEA15/SLC2A6/SLC5A3/SLC2A11/SLC2A9/GRB10/PRKCI/IGF1/SORT1/SLC2A5/SLC2A10/SORBS1	19
BP	GO:0016525	negative regulation of angiogenesis	29/2619	173/18670	0.1749	0.3735	0.2801	CXCL10/PTN/NOTCH1/STAT1/THBS4/HLA-G/SEMA4A/FOXC1/CX3CR1/SERPINE1/ANGPT2/TNMD/PPARG/ROCK1/TIE1/KRIT1/PLK2/AGT/PML/SEMA3E/HOXA5/NGFR/THBS2/ATF2/FOXJ2/COL4A2/CCR2/GPR4/SERPINF1	29
BP	GO:0032720	negative regulation of tumor necrosis factor production	13/2619	70/18670	0.1757	0.3735	0.2801	TNFAIP3/IRAK3/TREM2/IL27RA/SLAMF1/SYT11/PTPN22/TSPO/IGF1/GHSR/AXL/AKAP8/TWIST1	13
BP	GO:0034121	regulation of toll-like receptor signaling pathway	13/2619	70/18670	0.1757	0.3735	0.2801	TNFAIP3/IRAK3/IRF1/BIRC3/LILRA2/BIRC2/PTPN22/PELI1/TLR5/MFHAS1/HMGB1/GRAMD4/TYRO3	13
BP	GO:0061515	myeloid cell development	13/2619	70/18670	0.1757	0.3735	0.2801	FBXW7/KIT/EPB42/MED1/JMJD6/PTBP3/TYROBP/ARID4A/ABI1/ERCC2/EP300/SH2B3/TRIM58	13
BP	GO:1903305	regulation of regulated secretory pathway	27/2619	160/18670	0.1757	0.3735	0.2801	NOTCH1/MICAL1/RPH3AL/RIMS3/HLA-F/PREPL/PRKCB/SYT11/RAB27A/IL4R/PFN2/GSK3B/FGR/SYT17/FOXF1/RAC2/VAMP7/ADCY1/CACNB2/CACNA1D/SYT1/RAB15/SYN1/RAP1B/IL13RA2/CCR2/NAPA	27
BP	GO:0032602	chemokine production	16/2619	89/18670	0.1764	0.3735	0.2801	TREM2/RIPK2/IL4R/ADAM17/ELANE/POSTN/TUSC2/IFNG/IL6/EGR1/TNFSF4/LPL/HIF1A/IL6R/TRIM32/TWIST1	16
BP	GO:0000076	DNA replication checkpoint	4/2619	16/18670	0.1771	0.3735	0.2801	TOPBP1/DNA2/TIMELESS/RAD9A	4
BP	GO:0002739	regulation of cytokine secretion involved in immune response	4/2619	16/18670	0.1771	0.3735	0.2801	TNFRSF1B/MAPK3/ANGPT1/TNFRSF14	4
BP	GO:0006957	complement activation, alternative pathway	4/2619	16/18670	0.1771	0.3735	0.2801	C7/CFD/CR1/CFP	4
BP	GO:0010919	regulation of inositol phosphate biosynthetic process	4/2619	16/18670	0.1771	0.3735	0.2801	SNCA/PTH1R/GPER1/PTK2B	4
BP	GO:0019377	glycolipid catabolic process	4/2619	16/18670	0.1771	0.3735	0.2801	FUCA1/GM2A/NEU1/PSAP	4
BP	GO:0030214	hyaluronan catabolic process	4/2619	16/18670	0.1771	0.3735	0.2801	GUSB/HMMR/CD44/HEXA	4
BP	GO:0030889	negative regulation of B cell proliferation	4/2619	16/18670	0.1771	0.3735	0.2801	ATM/TNFRSF21/CTLA4/TYROBP	4
BP	GO:0032695	negative regulation of interleukin-12 production	4/2619	16/18670	0.1771	0.3735	0.2801	IRAK3/SLAMF1/NFKB1/TLR8	4
BP	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation	4/2619	16/18670	0.1771	0.3735	0.2801	FCHSD2/AP1AR/HIP1R/CYFIP1	4
BP	GO:0034975	protein folding in endoplasmic reticulum	4/2619	16/18670	0.1771	0.3735	0.2801	SUCO/EMC2/DNAJC3/HSPA5	4
BP	GO:0036124	histone H3-K9 trimethylation	4/2619	16/18670	0.1771	0.3735	0.2801	ARID4B/ATRX/ARID4A/SUV39H2	4
BP	GO:0042033	chemokine biosynthetic process	4/2619	16/18670	0.1771	0.3735	0.2801	ELANE/IFNG/IL6/EGR1	4
BP	GO:0042447	hormone catabolic process	4/2619	16/18670	0.1771	0.3735	0.2801	DIO3/IDE/YWHAH/DIO2	4
BP	GO:0042448	progesterone metabolic process	4/2619	16/18670	0.1771	0.3735	0.2801	DHRS9/EGR1/AKR1C3/AKR1C4	4
BP	GO:0043217	myelin maintenance	4/2619	16/18670	0.1771	0.3735	0.2801	CLU/CXCR4/SOD1/FA2H	4
BP	GO:0046325	negative regulation of glucose import	4/2619	16/18670	0.1771	0.3735	0.2801	ENPP1/PID1/PEA15/GRB10	4
BP	GO:0048385	regulation of retinoic acid receptor signaling pathway	4/2619	16/18670	0.1771	0.3735	0.2801	DHRS3/EZH2/PRAME/AKR1C3	4
BP	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter	4/2619	16/18670	0.1771	0.3735	0.2801	RIMS3/SYT11/SYT17/SYT1	4
BP	GO:0048820	hair follicle maturation	4/2619	16/18670	0.1771	0.3735	0.2801	RBPJ/FERMT1/ERCC2/GAL	4
BP	GO:0050755	chemokine metabolic process	4/2619	16/18670	0.1771	0.3735	0.2801	ELANE/IFNG/IL6/EGR1	4
BP	GO:0055012	ventricular cardiac muscle cell differentiation	4/2619	16/18670	0.1771	0.3735	0.2801	RXRA/CCNB1/CDK1/MYH10	4
BP	GO:0060965	negative regulation of gene silencing by miRNA	4/2619	16/18670	0.1771	0.3735	0.2801	PPARG/DND1/PPP3CA/NCOR1	4
BP	GO:0070863	positive regulation of protein exit from endoplasmic reticulum	4/2619	16/18670	0.1771	0.3735	0.2801	TMEM30A/CD81/SEC16A/EDEM1	4
BP	GO:0071871	response to epinephrine	4/2619	16/18670	0.1771	0.3735	0.2801	SNCA/KCNQ1/PENK/ATP2B4	4
BP	GO:0090036	regulation of protein kinase C signaling	4/2619	16/18670	0.1771	0.3735	0.2801	WNT11/CD40/VEGFA/SEZ6L	4
BP	GO:0097067	cellular response to thyroid hormone stimulus	4/2619	16/18670	0.1771	0.3735	0.2801	SIX1/KIT/MED1/GHSR	4
BP	GO:0097091	synaptic vesicle clustering	4/2619	16/18670	0.1771	0.3735	0.2801	CDH2/PCDH17/MAGI2/SYN1	4
BP	GO:0099116	tRNA 5'-end processing	4/2619	16/18670	0.1771	0.3735	0.2801	HSD17B10/POP7/RPP14/USP14	4
BP	GO:1900451	positive regulation of glutamate receptor signaling pathway	4/2619	16/18670	0.1771	0.3735	0.2801	PINK1/ADRB2/IFNG/CCR2	4
BP	GO:1902004	positive regulation of amyloid-beta formation	4/2619	16/18670	0.1771	0.3735	0.2801	CLU/GSAP/IFNG/EPHA4	4
BP	GO:2000846	regulation of corticosteroid hormone secretion	4/2619	16/18670	0.1771	0.3735	0.2801	AGT/TAC1/GAL/CRY1	4
BP	GO:2001170	negative regulation of ATP biosynthetic process	4/2619	16/18670	0.1771	0.3735	0.2801	NUPR1/CBFA2T3/DDIT4/PID1	4
BP	GO:2001224	positive regulation of neuron migration	4/2619	16/18670	0.1771	0.3735	0.2801	NIPBL/SEMA3A/ARHGEF2/FLNA	4
BP	GO:0050657	nucleic acid transport	32/2619	193/18670	0.1771	0.3735	0.2801	CETN2/HNRNPA2B1/NXF3/NUP160/RFTN1/IGF2BP3/THOC2/NUP153/DDX39A/THOC1/TPR/NUP50/SEC13/NMD3/RANBP2/NXF1/KIF5C/SNUPN/SRSF4/NUP210/HNRNPA1/SFPQ/NUP43/NDC1/SETD2/YTHDC1/NCBP2/EIF6/MVP/MRPL18/NUP98/NUP62	32
BP	GO:0050658	RNA transport	32/2619	193/18670	0.1771	0.3735	0.2801	CETN2/HNRNPA2B1/NXF3/NUP160/RFTN1/IGF2BP3/THOC2/NUP153/DDX39A/THOC1/TPR/NUP50/SEC13/NMD3/RANBP2/NXF1/KIF5C/SNUPN/SRSF4/NUP210/HNRNPA1/SFPQ/NUP43/NDC1/SETD2/YTHDC1/NCBP2/EIF6/MVP/MRPL18/NUP98/NUP62	32
BP	GO:0030148	sphingolipid biosynthetic process	18/2619	102/18670	0.179	0.3773	0.283	SPHK1/PRKD2/PEMT/CERS6/PRKD3/ASAH1/CERS4/UGCG/CERS2/ALDH3A2/SGMS1/PRKAA1/FA2H/ST8SIA2/SGPL1/VAPA/ALDH3B1/B4GALT3	18
BP	GO:0036498	IRE1-mediated unfolded protein response	12/2619	64/18670	0.1792	0.3775	0.2831	ATP6V0D1/KLHDC3/KDELR3/YIF1A/DDX11/TATDN2/EXTL2/EDEM1/DNAJC3/CXXC1/XBP1/HSPA5	12
BP	GO:0044783	G1 DNA damage checkpoint	12/2619	64/18670	0.1792	0.3775	0.2831	RFWD3/CRADD/CHEK2/ATM/PLK2/CCNB1/PML/GTSE1/CDK1/CDKN1A/EP300/RBL2	12
BP	GO:0016358	dendrite development	38/2619	233/18670	0.1793	0.3775	0.2832	PTN/SEMA4D/TNIK/SS18L1/SEMA3A/EZH2/DOCK10/BAIAP2/ASAP1/NCK2/ZNF365/APOE/GSK3B/TRAK1/BBS4/PARP6/SIPA1L1/YWHAH/CD3E/PLK2/CHRNA3/VAMP7/TLX2/CDC20/EPHA4/PPP3CA/CAMK1/ABI1/CDKL5/PAK2/CYFIP1/CAPRIN2/DSCAM/C21orf91/CAMK2B/ACTR2/BCL11A/NEDD4L	38
BP	GO:0046470	phosphatidylcholine metabolic process	15/2619	83/18670	0.1806	0.38	0.285	PNPLA6/LIPC/PEMT/PLA2G2D/PLA2G15/CSNK2B/PCTP/PLA2G4C/APOC1/PLBD1/LPCAT4/FABP3/LPIN1/STARD7/CHPT1	15
BP	GO:0060218	hematopoietic stem cell differentiation	15/2619	83/18670	0.1806	0.38	0.285	SFRP1/FOXC1/MEOX1/PSMB9/N4BP2L2/PUS7/PSMC2/PSMB6/PSMC3/PSMD8/PSMB5/BATF/PSMD10/ERCC2/TCF3	15
BP	GO:0071277	cellular response to calcium ion	15/2619	83/18670	0.1806	0.38	0.285	LGMN/ECT2/ALOX5AP/SYT11/GUCA1A/SYT17/CRHBP/AKR1C3/ADCY1/MCOLN1/PRKAA1/SYT1/RASGRP2/HSPA5/CPNE6	15
BP	GO:0050709	negative regulation of protein secretion	24/2619	141/18670	0.181	0.3806	0.2855	TNFAIP3/GBP1/SFRP1/CD200/BTN2A2/IL27RA/ANGPT1/SYT11/TNFRSF21/CARD8/APOE/PTPN22/RAB11FIP1/PTGER4/F2R/HADH/MAP4K4/GHSR/PML/PPP3CA/RHBDF2/INHBB/TLR8/SRGN	24
BP	GO:0010595	positive regulation of endothelial cell migration	22/2619	128/18670	0.181	0.3806	0.2855	LGMN/PRKD2/ANGPT1/ADAM17/AAMP/BMP4/CD40/HSPB1/PLK2/AGT/NOS3/FGF18/KDR/PDGFB/VEGFA/P2RX4/HMGB1/MAP3K3/HIF1A/CIB1/STAT5A/PTK2B	22
BP	GO:0046605	regulation of centrosome cycle	11/2619	58/18670	0.1825	0.3835	0.2876	MDM1/CHEK1/CHORDC1/PLK2/KIF11/CHMP2A/ALMS1/CHMP1B/KAT2B/SPICE1/NUP62	11
BP	GO:0061951	establishment of protein localization to plasma membrane	11/2619	58/18670	0.1825	0.3835	0.2876	MACF1/PREPL/ANK3/BBS1/VAMP3/SEC16A/VAMP7/OPTN/VAMP2/GOLGA4/GOLPH3	11
BP	GO:0090277	positive regulation of peptide hormone secretion	17/2619	96/18670	0.1836	0.3855	0.2891	JAK2/RPH3AL/SRI/MPC2/CD38/RBP4/BAD/EGFR/HFE/GPER1/ARRB1/OXCT1/SIRT3/ANO1/HIF1A/TARDBP/TCF7L2	17
BP	GO:0098876	vesicle-mediated transport to the plasma membrane	17/2619	96/18670	0.1836	0.3855	0.2891	MICALL1/ARL3/MACF1/PREPL/ANK3/BBS1/SNX17/VAMP3/EXOC2/SEC16A/VAMP7/OPTN/VAMP2/GOLGA4/RAB11B/GOLPH3/EXOC1	17
BP	GO:0032970	regulation of actin filament-based process	61/2619	388/18670	0.1839	0.386	0.2895	SFRP1/IQGAP2/ACTR3B/ECT2/ARPC1A/SRI/SMAD3/TMOD1/CDC42EP3/FGF13/FCHSD2/PFN2/BAIAP2/NCK2/STC1/ACTR3/CORO2B/LIMCH1/NTF3/CAPZA1/BIN1/EFNA5/RHOF/WNT11/ROCK1/KCNJ2/BBS4/PTGER4/S1PR1/RGS4/PPM1E/TAOK1/TMOD2/RND2/CLASP1/FHOD3/MAGEL2/MYOC/SCIN/ARHGAP35/CCR7/AP1AR/SEMA3E/MLST8/TMSB10/ALMS1/ARPC5L/AKAP9/NF2/RANGRF/TAC1/CTTN/AKAP13/RHOH/HIP1R/CYFIP1/LIMA1/FLNA/PTK2B/ARFGEF1/ACTR2	61
BP	GO:0002792	negative regulation of peptide secretion	25/2619	148/18670	0.1854	0.3872	0.2905	TNFAIP3/GBP1/SFRP1/CD200/BTN2A2/IL27RA/ANGPT1/SYT11/TNFRSF21/CARD8/APOE/PTPN22/RAB11FIP1/PTGER4/F2R/HADH/CRHBP/MAP4K4/GHSR/PML/PPP3CA/RHBDF2/INHBB/TLR8/SRGN	25
BP	GO:0051592	response to calcium ion	25/2619	148/18670	0.1854	0.3872	0.2905	LGMN/ECT2/ALOX5AP/SYT11/SDC1/BAD/EGFR/PENK/GUCA1A/SYT17/CRHBP/AKR1C3/ADCY1/PPP3CA/MCOLN1/PRKAA1/ANXA7/SYT1/MNAT1/RASGRP2/PTK2B/HNRNPD/HSPA5/KCNMB2/CPNE6	25
BP	GO:0060421	positive regulation of heart growth	10/2619	52/18670	0.1856	0.3872	0.2905	NOTCH1/PIM1/ZFPM2/IGF1/TBX5/CCNB1/RBPJ/PIN1/CDK1/ERBB4	10
BP	GO:1902373	negative regulation of mRNA catabolic process	10/2619	52/18670	0.1856	0.3872	0.2905	CIRBP/HNRNPA0/SLC11A1/MAPKAPK2/DND1/YBX1/TARDBP/MYD88/HNRNPD/DAZL	10
BP	GO:2000649	regulation of sodium ion transmembrane transporter activity	10/2619	52/18670	0.1856	0.3872	0.2905	SCN1B/ATP1B1/FXYD1/FXYD6/NETO2/KLHL24/ANK3/YWHAH/RANGRF/NEDD4L	10
BP	GO:2000772	regulation of cellular senescence	10/2619	52/18670	0.1856	0.3872	0.2905	HLA-G/ING2/PLK2/NAMPT/MAP3K3/KRAS/HMGA1/HMGA2/TWIST1/FBXO5	10
BP	GO:0030010	establishment of cell polarity	23/2619	135/18670	0.1859	0.3872	0.2905	UST/NDE1/FGF13/GSK3B/ARHGEF2/ROCK1/NDC80/FOXF1/NEK3/KRIT1/CDH5/PRKCI/CLASP1/SIPA1L3/LLGL2/CCR7/FERMT1/AMOTL2/WEE1/GOLPH3/PTK2B/RAP1B/ARFGEF1	23
BP	GO:1905477	positive regulation of protein localization to membrane	21/2619	122/18670	0.1859	0.3872	0.2905	PTN/TREM2/FIS1/BAD/EGFR/PRNP/PRKCH/ERBB2/GZMB/PPP1R13B/ANK3/GPER1/CD81/YWHAH/IFNG/PRKCI/TP53BP2/RANGRF/CIB1/LGALS3/SORBS1	21
BP	GO:0000423	mitophagy	5/2619	22/18670	0.1866	0.3872	0.2905	VPS13C/PINK1/ATG13/OPTN/CLEC16A	5
BP	GO:0000717	nucleotide-excision repair, DNA duplex unwinding	5/2619	22/18670	0.1866	0.3872	0.2905	CETN2/UBB/DDB2/ERCC2/GTF2H3	5
BP	GO:0001759	organ induction	5/2619	22/18670	0.1866	0.3872	0.2905	SIX1/HOXA11/AR/BMP4/HOXC11	5
BP	GO:0006379	mRNA cleavage	5/2619	22/18670	0.1866	0.3872	0.2905	POLR2I/RNASE4/CPSF7/NCBP2/CSTF2	5
BP	GO:0007063	regulation of sister chromatid cohesion	5/2619	22/18670	0.1866	0.3872	0.2905	NIPBL/DDX11/SMC5/ATRX/SFPQ	5
BP	GO:0009220	pyrimidine ribonucleotide biosynthetic process	5/2619	22/18670	0.1866	0.3872	0.2905	NME4/NME7/NME5/NME3/CTPS1	5
BP	GO:0010226	response to lithium ion	5/2619	22/18670	0.1866	0.3872	0.2905	CEBPA/IGFBP2/ADCY1/ID2/PTK2B	5
BP	GO:0030878	thyroid gland development	5/2619	22/18670	0.1866	0.3872	0.2905	SIX1/MAPK3/SMAD3/HOXA5/RAF1	5
BP	GO:0031281	positive regulation of cyclase activity	5/2619	22/18670	0.1866	0.3872	0.2905	MAPK3/TIMP2/GUCA1A/NOS3/CACNA1D	5
BP	GO:0031342	negative regulation of cell killing	5/2619	22/18670	0.1866	0.3872	0.2905	HLA-F/HLA-G/IL7R/PTPRC/HLA-E	5
BP	GO:0032402	melanosome transport	5/2619	22/18670	0.1866	0.3872	0.2905	MREG/RAB27A/BBS4/DCTN2/RAB11B	5
BP	GO:0033622	integrin activation	5/2619	22/18670	0.1866	0.3872	0.2905	CXCL13/PTGER4/FERMT2/MZB1/RASIP1	5
BP	GO:0034311	diol metabolic process	5/2619	22/18670	0.1866	0.3872	0.2905	GCH1/SPHK1/QDPR/PCBD1/ASAH1	5
BP	GO:0034643	establishment of mitochondrion localization, microtubule-mediated	5/2619	22/18670	0.1866	0.3872	0.2905	UCHL1/TRAK1/UBB/SPAST/HIF1A	5
BP	GO:0035584	calcium-mediated signaling using intracellular calcium source	5/2619	22/18670	0.1866	0.3872	0.2905	FIS1/PTPRC/PRNP/PTGFR/KDR	5
BP	GO:0035929	steroid hormone secretion	5/2619	22/18670	0.1866	0.3872	0.2905	AGT/TAC1/GDF9/GAL/CRY1	5
BP	GO:0042094	interleukin-2 biosynthetic process	5/2619	22/18670	0.1866	0.3872	0.2905	PTPRC/CD28/CD3E/GLMN/PRKCQ	5
BP	GO:0044321	response to leptin	5/2619	22/18670	0.1866	0.3872	0.2905	CCNA2/PID1/BBS4/UGCG/INHBB	5
BP	GO:0045943	positive regulation of transcription by RNA polymerase I	5/2619	22/18670	0.1866	0.3872	0.2905	DDX11/ERBB2/HEATR1/WDR43/ATF4	5
BP	GO:0047497	mitochondrion transport along microtubule	5/2619	22/18670	0.1866	0.3872	0.2905	UCHL1/TRAK1/UBB/SPAST/HIF1A	5
BP	GO:0060065	uterus development	5/2619	22/18670	0.1866	0.3872	0.2905	HOXA11/HOXA10/NIPBL/RBP4/CDKN1C	5
BP	GO:0060487	lung epithelial cell differentiation	5/2619	22/18670	0.1866	0.3872	0.2905	SOX9/RBPJ/AIMP2/HOXA5/CREB1	5
BP	GO:0060575	intestinal epithelial cell differentiation	5/2619	22/18670	0.1866	0.3872	0.2905	PRDM1/HIF1A/HOXA5/TYMS/CDKN1A	5
BP	GO:0070935	3'-UTR-mediated mRNA stabilization	5/2619	22/18670	0.1866	0.3872	0.2905	HNRNPA0/MAPKAPK2/TARDBP/MYD88/DAZL	5
BP	GO:0072643	interferon-gamma secretion	5/2619	22/18670	0.1866	0.3872	0.2905	RASGRP1/PTPN22/TCIRG1/BTN3A1/CD2	5
BP	GO:0005978	glycogen biosynthetic process	9/2619	46/18670	0.1882	0.3872	0.2905	PPP1R3C/ENPP1/PGM1/GSK3B/INSR/DYRK2/IGF1/PASK/SORBS1	9
BP	GO:0009250	glucan biosynthetic process	9/2619	46/18670	0.1882	0.3872	0.2905	PPP1R3C/ENPP1/PGM1/GSK3B/INSR/DYRK2/IGF1/PASK/SORBS1	9
BP	GO:0031648	protein destabilization	9/2619	46/18670	0.1882	0.3872	0.2905	FBXW7/SNCA/CCDC88C/PRNP/CHFR/PEX2/TRIM21/EP300/XBP1	9
BP	GO:0032527	protein exit from endoplasmic reticulum	9/2619	46/18670	0.1882	0.3872	0.2905	HERPUD1/UBE2J1/TMEM30A/SEC13/CD81/SEC16A/EDEM1/RANGRF/SEL1L	9
BP	GO:0033628	regulation of cell adhesion mediated by integrin	9/2619	46/18670	0.1882	0.3872	0.2905	CCL5/CXCL13/SERPINE1/ADA/CD3E/FERMT1/CIB1/PODXL/LPXN	9
BP	GO:0043277	apoptotic cell clearance	9/2619	46/18670	0.1882	0.3872	0.2905	TREM2/SPG11/MERTK/JMJD6/AXL/TYROBP/HMGB1/FCN1/TYRO3	9
BP	GO:0043330	response to exogenous dsRNA	9/2619	46/18670	0.1882	0.3872	0.2905	NFKBIA/IRAK3/MAPK3/RIPK2/COLEC12/RFTN1/IRF3/DDX1/DDX21	9
BP	GO:0031503	protein-containing complex localization	45/2619	281/18670	0.1882	0.3872	0.2905	IFT46/ARL3/HNRNPA2B1/USP46/ATR/RPGR/NXF3/NUP160/ATM/THOC2/NUP153/DDX39A/IFT52/THOC1/TPR/DYNLRB1/NUP50/SEC13/NMD3/RANBP2/NXF1/ADAM22/KIF5C/PCM1/GHSR/TNPO1/TYROBP/SRSF4/NUP210/CLUAP1/IFT140/BIRC5/SFPQ/NUP43/EXOC3/NDC1/SETD2/YTHDC1/NCBP2/IFT22/EIF6/EXOC1/NUP98/NUP62/DYNC2LI1	45
BP	GO:0042593	glucose homeostasis	39/2619	241/18670	0.189	0.3872	0.2905	PDK2/CEBPA/RPH3AL/FIS1/IGFBP5/SRI/MPC2/RBP4/BAD/INSR/EFNA5/CMA1/PPARG/RMI1/GPER1/PTPN2/ARRB1/OXCT1/POLG/PTPRN2/LRP5/MAP4K4/PCK2/ANO1/HECTD4/PPP3CA/SSTR5/HIF1A/NMB/PRKAA1/NGFR/RAF1/RAB11B/TCF7L2/XBP1/CRY1/SERPINF1/TH/PIK3CA	39
BP	GO:0001990	regulation of systemic arterial blood pressure by hormone	8/2619	40/18670	0.1902	0.3872	0.2905	CPA3/HSD11B2/CMA1/F2R/AGT/NOS3/CTSG/CORIN	8
BP	GO:0009268	response to pH	8/2619	40/18670	0.1902	0.3872	0.2905	LGMN/CA2/PKD2L1/MCOLN1/RAB11B/GPR4/SERPINF1/ARSB	8
BP	GO:0032467	positive regulation of cytokinesis	8/2619	40/18670	0.1902	0.3872	0.2905	CDC25B/ECT2/RACGAP1/CDC14A/AURKB/SSTR5/SPAST/NUP62	8
BP	GO:0042026	protein refolding	8/2619	40/18670	0.1902	0.3872	0.2905	PPIC/NKTR/HSPA6/PPIE/PPIB/HSPA2/HSPA5/PPIH	8
BP	GO:0001516	prostaglandin biosynthetic process	6/2619	28/18670	0.1904	0.3872	0.2905	HPGDS/PTGS1/TBXAS1/AKR1C3/PTGDS/CBR1	6
BP	GO:0001958	endochondral ossification	6/2619	28/18670	0.1904	0.3872	0.2905	FOXC1/BMP4/NAB1/PEX7/FGF18/MMP13	6
BP	GO:0003180	aortic valve morphogenesis	6/2619	28/18670	0.1904	0.3872	0.2905	NOTCH1/SOX9/BMP4/ROCK1/NOS3/TWIST1	6
BP	GO:0006760	folic acid-containing compound metabolic process	6/2619	28/18670	0.1904	0.3872	0.2905	GCH1/FOLR1/MTHFD2/GGH/FOLR2/TYMS	6
BP	GO:0034698	response to gonadotropin	6/2619	28/18670	0.1904	0.3872	0.2905	NOTCH1/CCNA2/EFNA5/PAPPA/GHSR/ASNS	6
BP	GO:0035116	embryonic hindlimb morphogenesis	6/2619	28/18670	0.1904	0.3872	0.2905	PITX1/NOTCH1/BMP4/MED1/OSR2/TWIST1	6
BP	GO:0035456	response to interferon-beta	6/2619	28/18670	0.1904	0.3872	0.2905	AIM2/STAT1/IRF1/NDUFA13/IFITM2/IFI16	6
BP	GO:0036075	replacement ossification	6/2619	28/18670	0.1904	0.3872	0.2905	FOXC1/BMP4/NAB1/PEX7/FGF18/MMP13	6
BP	GO:0042634	regulation of hair cycle	6/2619	28/18670	0.1904	0.3872	0.2905	NIPBL/DKK4/FERMT1/FA2H/GAL/SMO	6
BP	GO:0046457	prostanoid biosynthetic process	6/2619	28/18670	0.1904	0.3872	0.2905	HPGDS/PTGS1/TBXAS1/AKR1C3/PTGDS/CBR1	6
BP	GO:0048679	regulation of axon regeneration	6/2619	28/18670	0.1904	0.3872	0.2905	PTN/PTPRF/CERS2/KLK8/EPHA4/LRIG2	6
BP	GO:0050686	negative regulation of mRNA processing	6/2619	28/18670	0.1904	0.3872	0.2905	HNRNPA2B1/BARD1/HNRNPK/SFSWAP/SRSF4/CDK9	6
BP	GO:0086013	membrane repolarization during cardiac muscle cell action potential	6/2619	28/18670	0.1904	0.3872	0.2905	ATP1B1/KCNQ1/KCNJ2/KCNJ8/KCNN2/FLNA	6
BP	GO:1900543	negative regulation of purine nucleotide metabolic process	6/2619	28/18670	0.1904	0.3872	0.2905	NUPR1/SNCA/CBFA2T3/DDIT4/PID1/TSPO	6
BP	GO:1902668	negative regulation of axon guidance	6/2619	28/18670	0.1904	0.3872	0.2905	SEMA4D/SEMA4A/SEMA3A/SEMA4C/SEMA3F/SEMA3E	6
BP	GO:0070252	actin-mediated cell contraction	20/2619	116/18670	0.191	0.3872	0.2905	SCN1B/SNTA1/MYL6B/SRI/KCNQ1/TMOD1/STC1/BIN1/ROCK1/KCNJ2/MYL3/MYL4/CACNB2/KCNJ8/KCNN2/EMP2/MYH4/CACNA1D/FLNA/NEDD4L	20
BP	GO:0003206	cardiac chamber morphogenesis	22/2619	129/18670	0.191	0.3872	0.2905	NOTCH1/DHRS3/FOXC1/SOS1/RBP4/SMARCD3/RXRA/BMP4/WNT11/MED1/MYL3/FOXF1/RBM15/ZFPM2/NOS3/TBX5/RBPJ/CPE/HIF1A/ID2/SMO/FZD2	22
BP	GO:0051961	negative regulation of nervous system development	50/2619	315/18670	0.191	0.3872	0.2905	BRINP1/PTN/NOTCH1/DIO3/SOX9/STMN2/GAK/SEMA4D/ASPM/SEMA4A/SPOCK1/CD38/SEMA3A/FGF13/TNFRSF21/ASAP1/ZNF365/APOE/GSK3B/SEMA4C/ARHGEF2/DGUOK/MED1/PMP22/YWHAH/ID4/CERS2/PLK2/KLK8/PCM1/SEMA3F/TSPO/MAP4K4/IL6/TLX2/ITM2C/EPHA4/NR2F1/SEMA3E/PPP3CA/CIB1/SIX3/NGFR/OLIG2/ID2/ID3/ERBB4/COL3A1/BCL11A/LRIG2	50
BP	GO:0010922	positive regulation of phosphatase activity	7/2619	34/18670	0.1912	0.3872	0.2905	JAK2/SMAD3/PTPRC/MTMR9/MAGI2/PPP1R12A/IFNG	7
BP	GO:0019228	neuronal action potential	7/2619	34/18670	0.1912	0.3872	0.2905	GPR88/ANK3/GPER1/P2RX4/SCN9A/KCNMB2/SCN3A	7
BP	GO:0031128	developmental induction	7/2619	34/18670	0.1912	0.3872	0.2905	SIX1/HOXA11/AR/SOX9/BMP4/SIX3/HOXC11	7
BP	GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator	7/2619	34/18670	0.1912	0.3872	0.2905	ATR/ATM/CD44/SMYD2/PLA2R1/PSMD10/TWIST1	7
BP	GO:0045920	negative regulation of exocytosis	7/2619	34/18670	0.1912	0.3872	0.2905	NOTCH1/SNCA/HLA-F/FOXF1/RAP1B/IL13RA2/CCR2	7
BP	GO:0048048	embryonic eye morphogenesis	7/2619	34/18670	0.1912	0.3872	0.2905	EFEMP1/ARID1A/ALDH1A3/PHACTR4/SIX3/TH/TWIST1	7
BP	GO:0048566	embryonic digestive tract development	7/2619	34/18670	0.1912	0.3872	0.2905	NIPBL/TCF7/ADA/FOXF1/SIX2/ID2/CXCL8	7
BP	GO:0071402	cellular response to lipoprotein particle stimulus	7/2619	34/18670	0.1912	0.3872	0.2905	ADAM17/APOE/PPARG/CD81/LPL/MYD88/NPC1	7
BP	GO:0097009	energy homeostasis	7/2619	34/18670	0.1912	0.3872	0.2905	UBB/PRKAA1/CRTC3/AMPD3/PASK/NR1D2/PIK3CA	7
BP	GO:0098901	regulation of cardiac muscle cell action potential	7/2619	34/18670	0.1912	0.3872	0.2905	FGF13/BIN1/ANK3/AKAP9/RANGRF/CXADR/FLNA	7
BP	GO:0006909	phagocytosis	58/2619	369/18670	0.1913	0.3872	0.2905	IL15RA/DYSF/SPHK1/TREM2/MAPK3/ARPC1A/PLCG2/COLEC12/SLAMF1/IL15/IL2RG/SYT11/RAB27A/PTPRC/SPG11/ITGAL/BAIAP2/MERTK/CDC42SE1/ACTR3/GULP1/PECAM1/LMAN2/IGLV1-44/IGHM/CYFIP2/PPARG/FGR/JMJD6/CD93/ELANE/TRBC1/TUSC2/IFNG/WIPF1/PIK3CB/IL2RB/VAMP7/CD247/AXL/TYROBP/SLC11A1/HMGB1/C4BPB/IGLL5/IGLC1/SOD1/ABI1/MBL2/RAB20/FCN1/TYRO3/CYFIP1/MYD88/CD3G/ICAM3/ACTR2/PIK3CA	58
BP	GO:0065004	protein-DNA complex assembly	40/2619	248/18670	0.1914	0.3872	0.2905	CETN2/NAP1L3/SOX9/ATF7IP/BRF2/NAP1L2/ORC3/RPA1/SART3/SET/RPA3/PSMC2/DAXX/CENPE/GTF2A2/NASP/CCNH/PSMC3/MIS12/TAF7/ATRX/UBB/HMGB1/HJURP/DDB2/CENPT/KAT6A/SMARCA5/ERCC2/TSPYL1/CREB1/CENPC/MNAT1/TSPYL5/GTF2H3/BAZ2A/UBN1/CENPF/GTF3C5/POGZ	40
BP	GO:2000181	negative regulation of blood vessel morphogenesis	29/2619	175/18670	0.1918	0.3872	0.2905	CXCL10/PTN/NOTCH1/STAT1/THBS4/HLA-G/SEMA4A/FOXC1/CX3CR1/SERPINE1/ANGPT2/TNMD/PPARG/ROCK1/TIE1/KRIT1/PLK2/AGT/PML/SEMA3E/HOXA5/NGFR/THBS2/ATF2/FOXJ2/COL4A2/CCR2/GPR4/SERPINF1	29
BP	GO:0000050	urea cycle	3/2619	11/18670	0.1922	0.3872	0.2905	CEBPA/ASS1/CPS1	3
BP	GO:0001778	plasma membrane repair	3/2619	11/18670	0.1922	0.3872	0.2905	DYSF/SYT11/MYH10	3
BP	GO:0002638	negative regulation of immunoglobulin production	3/2619	11/18670	0.1922	0.3872	0.2905	PARP3/THOC1/IL13RA2	3
BP	GO:0002730	regulation of dendritic cell cytokine production	3/2619	11/18670	0.1922	0.3872	0.2905	NOD2/DDX1/DDX21	3
BP	GO:0002887	negative regulation of myeloid leukocyte mediated immunity	3/2619	11/18670	0.1922	0.3872	0.2905	FOXF1/IL13RA2/CCR2	3
BP	GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	3/2619	11/18670	0.1922	0.3872	0.2905	PTPRC/CR1/C4BPB	3
BP	GO:0006681	galactosylceramide metabolic process	3/2619	11/18670	0.1922	0.3872	0.2905	FA2H/PSAP/B4GALT3	3
BP	GO:0007256	activation of JNKK activity	3/2619	11/18670	0.1922	0.3872	0.2905	RIPK2/TNIK/MAP3K11	3
BP	GO:0009950	dorsal/ventral axis specification	3/2619	11/18670	0.1922	0.3872	0.2905	SFRP1/MDFI/CXXC4	3
BP	GO:0010172	embryonic body morphogenesis	3/2619	11/18670	0.1922	0.3872	0.2905	MAB21L2/ZNF281/CLASP1	3
BP	GO:0018095	protein polyglutamylation	3/2619	11/18670	0.1922	0.3872	0.2905	TTLL4/TTLL1/TPGS2	3
BP	GO:0021534	cell proliferation in hindbrain	3/2619	11/18670	0.1922	0.3872	0.2905	RORA/EGF/PSMG1	3
BP	GO:0021561	facial nerve development	3/2619	11/18670	0.1922	0.3872	0.2905	SIX1/SEMA3A/SEMA3F	3
BP	GO:0021610	facial nerve morphogenesis	3/2619	11/18670	0.1922	0.3872	0.2905	SIX1/SEMA3A/SEMA3F	3
BP	GO:0032060	bleb assembly	3/2619	11/18670	0.1922	0.3872	0.2905	PMP22/ROCK1/EMP2	3
BP	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase	3/2619	11/18670	0.1922	0.3872	0.2905	IVD/ETFB/ACADM	3
BP	GO:0035933	glucocorticoid secretion	3/2619	11/18670	0.1922	0.3872	0.2905	TAC1/GAL/CRY1	3
BP	GO:0040015	negative regulation of multicellular organism growth	3/2619	11/18670	0.1922	0.3872	0.2905	LGMN/ADRB2/STC2	3
BP	GO:0042023	DNA endoreduplication	3/2619	11/18670	0.1922	0.3872	0.2905	FBXW7/SMC1A/FBXO5	3
BP	GO:0043117	positive regulation of vascular permeability	3/2619	11/18670	0.1922	0.3872	0.2905	TACR2/VEGFA/CXCR2	3
BP	GO:0044793	negative regulation by host of viral process	3/2619	11/18670	0.1922	0.3872	0.2905	CCL8/CCNK/VAPA	3
BP	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly	3/2619	11/18670	0.1922	0.3872	0.2905	PSMC2/PSMC3/CREB1	3
BP	GO:0046886	positive regulation of hormone biosynthetic process	3/2619	11/18670	0.1922	0.3872	0.2905	IFNG/EGR1/HIF1A	3
BP	GO:0048096	chromatin-mediated maintenance of transcription	3/2619	11/18670	0.1922	0.3872	0.2905	CHEK1/ARID1A/PADI2	3
BP	GO:0051673	membrane disruption in other organism	3/2619	11/18670	0.1922	0.3872	0.2905	DEFA6/GSDMD/DEFA5	3
BP	GO:0055015	ventricular cardiac muscle cell development	3/2619	11/18670	0.1922	0.3872	0.2905	CCNB1/CDK1/MYH10	3
BP	GO:0060439	trachea morphogenesis	3/2619	11/18670	0.1922	0.3872	0.2905	MAPK3/BMP4/HOXA5	3
BP	GO:0060525	prostate glandular acinus development	3/2619	11/18670	0.1922	0.3872	0.2905	SFRP1/NOTCH1/RXRA	3
BP	GO:0060736	prostate gland growth	3/2619	11/18670	0.1922	0.3872	0.2905	AR/SOX9/PSAP	3
BP	GO:0060947	cardiac vascular smooth muscle cell differentiation	3/2619	11/18670	0.1922	0.3872	0.2905	NOTCH1/GPER1/VEGFA	3
BP	GO:0061085	regulation of histone H3-K27 methylation	3/2619	11/18670	0.1922	0.3872	0.2905	MTF2/EED/OGT	3
BP	GO:0061314	Notch signaling involved in heart development	3/2619	11/18670	0.1922	0.3872	0.2905	NOTCH1/GALNT11/RBPJ	3
BP	GO:0070269	pyroptosis	3/2619	11/18670	0.1922	0.3872	0.2905	AIM2/GSDMB/GSDMD	3
BP	GO:0070278	extracellular matrix constituent secretion	3/2619	11/18670	0.1922	0.3872	0.2905	NOTCH1/TNFRSF1B/AGT	3
BP	GO:0070471	uterine smooth muscle contraction	3/2619	11/18670	0.1922	0.3872	0.2905	TACR2/GPER1/AGT	3
BP	GO:0070933	histone H4 deacetylation	3/2619	11/18670	0.1922	0.3872	0.2905	RCOR1/HDAC1/SIRT7	3
BP	GO:0072310	glomerular epithelial cell development	3/2619	11/18670	0.1922	0.3872	0.2905	BMP4/MAGI2/PODXL	3
BP	GO:0072321	chaperone-mediated protein transport	3/2619	11/18670	0.1922	0.3872	0.2905	CLU/PEX19/TIMM10	3
BP	GO:0072611	interleukin-13 secretion	3/2619	11/18670	0.1922	0.3872	0.2905	TNFRSF21/IL17RB/IL17RA	3
BP	GO:0072711	cellular response to hydroxyurea	3/2619	11/18670	0.1922	0.3872	0.2905	DDX11/ATRX/TIMELESS	3
BP	GO:0098883	synapse pruning	3/2619	11/18670	0.1922	0.3872	0.2905	TREM2/CX3CR1/EPHA4	3
BP	GO:1901660	calcium ion export	3/2619	11/18670	0.1922	0.3872	0.2905	ATP2B4/LETM1/ATP2B1	3
BP	GO:1902065	response to L-glutamate	3/2619	11/18670	0.1922	0.3872	0.2905	BAIAP2/CREB1/BCL11A	3
BP	GO:1902805	positive regulation of synaptic vesicle transport	3/2619	11/18670	0.1922	0.3872	0.2905	CACNB2/CACNA1D/SYT1	3
BP	GO:1903977	positive regulation of glial cell migration	3/2619	11/18670	0.1922	0.3872	0.2905	TREM2/P2RX4/CCR2	3
BP	GO:1904468	negative regulation of tumor necrosis factor secretion	3/2619	11/18670	0.1922	0.3872	0.2905	IL27RA/SYT11/GHSR	3
BP	GO:1905941	positive regulation of gonad development	3/2619	11/18670	0.1922	0.3872	0.2905	SOX9/SEMA3A/ZFPM2	3
BP	GO:2000551	regulation of T-helper 2 cell cytokine production	3/2619	11/18670	0.1922	0.3872	0.2905	CD81/IL6/XCL1	3
BP	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	3/2619	11/18670	0.1922	0.3872	0.2905	JAK2/SMAD3/FAS	3
BP	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	55/2619	349/18670	0.1929	0.3884	0.2914	SFRP1/NOTCH1/FOLR1/MAPK3/SMAD3/GOT1/TMEM100/HIVEP1/MTMR4/ZFYVE16/ADAM17/NEO1/LTBP3/TRIM33/HFE/HTRA1/ING2/BMP4/GDF5/MAGI2/ADAMTSL2/LEF1/RNF111/CSNK2B/ZNF451/HPGD/FKBP8/FERMT2/CDH5/COMP/NBL1/CDKN1C/CILP/EGR1/PML/RBPJ/CHRDL1/TGIF2/LNPEP/PIN1/FUT8/UBB/FERMT1/NLK/PTPRK/LTBP4/USP9X/GDF9/ITGB5/CREB1/EP300/COL3A1/INHBB/HSPA5/ZNF423	55
BP	GO:1905897	regulation of response to endoplasmic reticulum stress	15/2619	84/18670	0.1931	0.3888	0.2916	NUPR1/CLU/HERPUD1/UBE2J1/NCK2/CREB3/PTPN2/ATF6/EDEM1/NFE2L1/DNAJC3/XBP1/HSPA5/DDIT3/USP14	15
BP	GO:0030833	regulation of actin filament polymerization	27/2619	162/18670	0.1934	0.389	0.2918	IQGAP2/ACTR3B/ARPC1A/TMOD1/CDC42EP3/FCHSD2/PFN2/BAIAP2/NCK2/ACTR3/CAPZA1/BIN1/BBS4/TMOD2/FHOD3/MAGEL2/SCIN/CCR7/AP1AR/TMSB10/ARPC5L/CTTN/HIP1R/CYFIP1/PTK2B/ARFGEF1/ACTR2	27
BP	GO:0006026	aminoglycan catabolic process	12/2619	65/18670	0.1935	0.389	0.2918	FUCA1/GPC5/GUSB/SDC1/HMMR/NAGLU/CD44/HEXA/VCAN/SGSH/KERA/ARSB	12
BP	GO:0051148	negative regulation of muscle cell differentiation	12/2619	65/18670	0.1935	0.389	0.2918	CXCL10/NOTCH1/CFLAR/DNMT1/EZH2/RGS4/CTDP1/EREG/PDGFB/XBP1/FZD7/BDNF	12
BP	GO:0072665	protein localization to vacuole	12/2619	65/18670	0.1935	0.389	0.2918	TNFAIP3/GBP1/VPS13C/CLU/VPS37C/ZFYVE16/GNPTAB/VTI1B/CD81/VAMP7/TRAPPC8/AP4M1	12
BP	GO:0016311	dephosphorylation	74/2619	478/18670	0.1937	0.3894	0.292	PTPRE/THTPA/CDC25B/DUSP5/PTN/HDDC2/EYA2/PPP1R3C/JAK2/SEMA4D/THNSL2/DAPP1/SMAD3/DUSP6/EPHX2/CAMTA1/LILRB2/MTMR4/PTPRF/PTPRC/G6PC3/MTMR9/NT5C2/DLGAP5/SYNJ1/PINK1/GSK3B/PTPN7/PPP6R3/SET/CTDSPL/RNGTT/RRP1B/MAGI2/MTMR6/SFI1/PTPN22/ROCK1/SHOC2/PPP4R1/CDC14A/PPP1R16B/PFKFB3/PTPN2/SSH3/CDH5/PPP1R12A/IFNG/LCK/PPM1E/PTPRN2/CTDP1/CILP/PSPH/MTMR1/DUSP2/MFHAS1/PIN1/ANKLE2/ACP6/PPP3CA/PPM1B/PTPRK/ACP1/PHACTR4/NT5E/ENSA/LGALS3/INPP5E/PTPRH/PHLPP1/STYXL1/LPIN1/PPA2	74
BP	GO:0032231	regulation of actin filament bundle assembly	17/2619	97/18670	0.1953	0.3924	0.2943	SFRP1/SMAD3/PFN2/CORO2B/LIMCH1/WNT11/ROCK1/BBS4/PTGER4/S1PR1/PPM1E/CLASP1/MYOC/ALMS1/NF2/TAC1/FLNA	17
BP	GO:0043414	macromolecule methylation	49/2619	309/18670	0.1958	0.3932	0.2949	MTF2/JARID2/SUZ12/WDR61/DNMT1/EZH2/ARID4B/ATF7IP/HSD17B10/METTL8/TARBP1/METTL22/PRMT5/CMTR1/RLF/SETD5/LCMT1/KDM3A/SETMAR/TRMT112/SMYD2/AUTS2/GATAD2A/RBM15/WDR5B/SETD1B/MYC/ATRX/METTL4/VCPKMT/SATB1/EED/DIMT1/PAXBP1/ARID4A/OGT/HEMK1/SETD2/PRDM4/SUV39H2/CXXC1/TFB2M/PIWIL2/BAZ2A/TRMT5/MEPCE/NSUN6/PIK3CA/TRMT13	49
BP	GO:0006024	glycosaminoglycan biosynthetic process	19/2619	110/18670	0.1962	0.3938	0.2953	GPC5/UST/ANGPT1/SDC1/B4GALT2/EGF/EXT2/NFKB1/HEXA/ST3GAL2/CHST15/EXTL2/B4GALT7/PDGFB/HAS2/VCAN/CHST12/KERA/B4GALT3	19
BP	GO:0006939	smooth muscle contraction	19/2619	110/18670	0.1962	0.3938	0.2953	SPHK1/TACR2/CD38/ADA/KIT/HTR2B/ROCK1/GPER1/F2R/ADRB2/CHRNA3/AGT/COMP/GHSR/PLCE1/SOD1/CTTN/ATP2B4/ATP2B1	19
BP	GO:0033559	unsaturated fatty acid metabolic process	19/2619	110/18670	0.1962	0.3938	0.2953	HPGDS/LTC4S/PTGS1/TBXAS1/MAPK3/ALOX5AP/EPHX2/DECR2/CES2/HPGD/PLA2G4C/SCD5/SCP2/AKR1C3/PTGDS/ACOX1/ACOT8/CBR1/AKR1C4	19
BP	GO:0002062	chondrocyte differentiation	21/2619	123/18670	0.1963	0.3938	0.2954	HOXA11/EFEMP1/SCARA3/WNT5B/SOX9/SMAD3/PTH1R/LTBP3/RUNX3/BMP4/GDF5/OSR2/COMP/FGF18/SIX2/ZNF219/SCIN/COL6A3/MBL2/MAF/HMGA2	21
BP	GO:0033500	carbohydrate homeostasis	39/2619	242/18670	0.1964	0.3938	0.2954	PDK2/CEBPA/RPH3AL/FIS1/IGFBP5/SRI/MPC2/RBP4/BAD/INSR/EFNA5/CMA1/PPARG/RMI1/GPER1/PTPN2/ARRB1/OXCT1/POLG/PTPRN2/LRP5/MAP4K4/PCK2/ANO1/HECTD4/PPP3CA/SSTR5/HIF1A/NMB/PRKAA1/NGFR/RAF1/RAB11B/TCF7L2/XBP1/CRY1/SERPINF1/TH/PIK3CA	39
BP	GO:0038095	Fc-epsilon receptor signaling pathway	28/2619	169/18670	0.1971	0.3952	0.2964	MS4A2/MAPK3/PLCG2/SKP1/MALT1/FCER1A/SOS1/PSMB9/ITK/IGLV1-44/PSMC2/NFKB1/PSMB6/CHUK/PIK3CB/PSMC3/PSMD8/PRKCQ/PSMB5/PPP3CA/IGLC1/LAT/PSMD10/IKBKG/PAK2/BCL10/LCP2/PIK3CA	28
BP	GO:0006898	receptor-mediated endocytosis	50/2619	316/18670	0.1975	0.3955	0.2966	MICALL1/FOLR1/LRP1B/TFRC/GAK/PLCG2/COLEC12/ANGPT1/SNCA/CLU/USP46/SYT11/LRPAP1/APOL1/HSPH1/EGF/FCHSD2/SERPINE1/APOE/INSR/RABEPK/NTF3/AP2M1/HFE/IGLV1-44/HTR2B/MAGI2/SELE/HNRNPK/LRP3/SNX17/ARRB1/ADRB2/CD81/FOLR2/APOC1/CD63/PIK3CB/AP1S1/VEGFA/PLA2R1/CXCR2/IGLC1/HBB/CTTN/HIP1R/ASGR1/CXCL8/LMBR1L/DNAJC13	50
BP	GO:0008333	endosome to lysosome transport	11/2619	59/18670	0.1978	0.3955	0.2966	DENND3/BIN1/TRAK1/ADRB2/VPS16/VAMP7/GPRASP1/SORT1/HOOK2/CLEC16A/HMGXB4	11
BP	GO:0031102	neuron projection regeneration	11/2619	59/18670	0.1978	0.3955	0.2966	PTN/FOLR1/JAK2/PTPRF/HGF/CERS2/KLK8/TSPO/MAP4K4/EPHA4/LRIG2	11
BP	GO:0045843	negative regulation of striated muscle tissue development	11/2619	59/18670	0.1978	0.3955	0.2966	JARID2/RBP4/BMP4/LEF1/RGS4/MAPK11/CTDP1/TBX5/LUC7L/FZD7/TWIST1	11
BP	GO:0072413	signal transduction involved in mitotic cell cycle checkpoint	11/2619	59/18670	0.1978	0.3955	0.2966	CRADD/CHEK2/ATM/PLK2/CCNB1/PML/GTSE1/CDK1/CDKN1A/EP300/RBL2	11
BP	GO:0097755	positive regulation of blood vessel diameter	11/2619	59/18670	0.1978	0.3955	0.2966	GCH1/EPHX2/EGFR/APOE/GPX1/GPER1/ADRB2/AGT/NOS3/CPS1/SOD1	11
BP	GO:1902402	signal transduction involved in mitotic DNA damage checkpoint	11/2619	59/18670	0.1978	0.3955	0.2966	CRADD/CHEK2/ATM/PLK2/CCNB1/PML/GTSE1/CDK1/CDKN1A/EP300/RBL2	11
BP	GO:1902403	signal transduction involved in mitotic DNA integrity checkpoint	11/2619	59/18670	0.1978	0.3955	0.2966	CRADD/CHEK2/ATM/PLK2/CCNB1/PML/GTSE1/CDK1/CDKN1A/EP300/RBL2	11
BP	GO:0031016	pancreas development	14/2619	78/18670	0.1981	0.3957	0.2968	SOX9/BAD/GSK3B/INSR/BMP4/FOXF1/WLS/INSM1/IL6/IL6R/TCF7L2/XBP1/NR5A2/SMO	14
BP	GO:0033143	regulation of intracellular steroid hormone receptor signaling pathway	14/2619	78/18670	0.1981	0.3957	0.2968	SFRP1/AR/UFSP2/CYP7B1/MED1/PHB/LMO3/BUD31/NCOR1/HDAC1/RNF14/EP300/CRY1/KANK2	14
BP	GO:0043407	negative regulation of MAP kinase activity	14/2619	78/18670	0.1981	0.3957	0.2968	DUSP5/SFRP1/IRAK3/DUSP6/UCHL1/APOE/LAX1/BMP4/DNAJA1/PTPN22/RGS4/DUSP2/SH2B3/NUP62	14
BP	GO:0045926	negative regulation of growth	40/2619	249/18670	0.1987	0.3968	0.2976	SFRP1/NOTCH1/JARID2/LGMN/WWC3/ENPP1/IGFBP5/SEMA4D/SMAD3/SEMA4A/NDUFA13/SEMA3A/FGF13/RBP4/CDKN2C/BMP4/SEMA4C/WNT11/PPARG/PHB/CRYAB/ADRB2/RGS4/AGT/MAPK11/SEMA3F/CTDP1/TBX5/CRLF3/PML/SEMA3E/HIF1A/GDF9/TNK1/NDUFS3/GAL/CDKN1A/CAPRIN2/BCL11A/STC2	40
BP	GO:0045639	positive regulation of myeloid cell differentiation	16/2619	91/18670	0.2006	0.4003	0.3003	TREM2/STAT1/CTNNBIP1/LEF1/MED1/IFNG/TRIB1/TYROBP/ZNF16/CA2/SCIN/HIF1A/HOXA5/CREB1/ID2/TRIM58	16
BP	GO:1901992	positive regulation of mitotic cell cycle phase transition	16/2619	91/18670	0.2006	0.4003	0.3003	CDC25B/CDC7/ADAM17/DLGAP5/EGFR/SMARCD3/CDK4/CCNB1/RAD51C/DTL/CDK1/CCND2/HSPA2/RAD51B/MEPCE/FBXO5	16
BP	GO:0008033	tRNA processing	22/2619	130/18670	0.2013	0.4016	0.3012	TYW1/HSD17B10/METTL8/TARBP1/ELP5/PUS7/TRMT112/POP7/ELP3/DDX1/PUS1/DUS4L/SEPHS1/OSGEP/RPP14/TRMT5/CSTF2/USP14/NSUN6/THUMPD1/RTCB/TRMT13	22
BP	GO:0051153	regulation of striated muscle cell differentiation	20/2619	117/18670	0.2018	0.4025	0.3019	CXCL9/SIK1/CXCL10/NOTCH1/IL4R/CFLAR/EZH2/BMP4/MAML1/RGS4/CTDP1/IGF1/RBPJ/PIN1/TNFSF14/AKAP13/TRIM32/XBP1/FZD7/BDNF	20
BP	GO:0032715	negative regulation of interleukin-6 production	10/2619	53/18670	0.2019	0.4025	0.3019	TNFAIP3/IRAK3/CD200/IL27RA/SLAMF1/SYT11/HGF/PTPN22/ARRB1/GHSR	10
BP	GO:0045661	regulation of myoblast differentiation	10/2619	53/18670	0.2019	0.4025	0.3019	CXCL9/CXCL10/NOTCH1/MAP3K5/SOX9/MBNL3/BMP4/TNFSF14/ID3/DDIT3	10
BP	GO:0002532	production of molecular mediator involved in inflammatory response	13/2619	72/18670	0.2032	0.4041	0.3031	SLAMF8/IL4R/IDO1/SERPINE1/CD96/C5orf30/VAMP7/CUEDC2/NOD2/IL17RC/PRDX2/MYD88/IL17RA	13
BP	GO:0006305	DNA alkylation	13/2619	72/18670	0.2032	0.4041	0.3031	DNMT1/EZH2/ATF7IP/PRMT5/RLF/GATAD2A/MYC/ATRX/METTL4/HEMK1/PIWIL2/BAZ2A/PIK3CA	13
BP	GO:0006306	DNA methylation	13/2619	72/18670	0.2032	0.4041	0.3031	DNMT1/EZH2/ATF7IP/PRMT5/RLF/GATAD2A/MYC/ATRX/METTL4/HEMK1/PIWIL2/BAZ2A/PIK3CA	13
BP	GO:0032272	negative regulation of protein polymerization	13/2619	72/18670	0.2032	0.4041	0.3031	STMN2/SNCA/TMOD1/PFN2/CAPZA1/BBS4/CDH5/TMOD2/FHOD3/SCIN/TMSB10/HIP1R/ARFGEF1	13
BP	GO:0061035	regulation of cartilage development	13/2619	72/18670	0.2032	0.4041	0.3031	HOXA11/EFEMP1/SOX9/SMAD3/LTBP3/BMP4/GDF5/WNT11/FGF18/SIX2/ZNF219/SCIN/MAF	13
BP	GO:1903556	negative regulation of tumor necrosis factor superfamily cytokine production	13/2619	72/18670	0.2032	0.4041	0.3031	TNFAIP3/IRAK3/TREM2/IL27RA/SLAMF1/SYT11/PTPN22/TSPO/IGF1/GHSR/AXL/AKAP8/TWIST1	13
BP	GO:1903747	regulation of establishment of protein localization to mitochondrion	13/2619	72/18670	0.2032	0.4041	0.3031	FBXW7/MICALL2/BAD/PINK1/GZMB/DNAJA1/PPP1R13B/YWHAH/TP53BP2/RAC2/ATG13/PRKAA1/UBL5	13
BP	GO:0043547	positive regulation of GTPase activity	63/2619	405/18670	0.2038	0.4052	0.3039	SFRP1/TBC1D9/CCL5/ECT2/RASGRP1/SEMA4D/CXCL13/GIT2/CCL18/ALDH1A1/RGS1/SOS1/EZH2/RALGAPB/DOCK10/ASAP1/RACGAP1/CHN1/NEDD9/GSK3B/RASGRP3/NTF3/ERBB2/HTR2B/WNT11/NUP50/DENND1B/RABEP2/CD40/RANBP2/SIPA1L1/ARRB1/S1PR1/F2R/ACAP1/NTRK1/CCL8/RABGAP1L/ARHGAP19/ARAP3/RGS4/TBC1D16/ARHGEF7/RAPGEF6/MAP4K4/SIPA1L3/ACAP2/XCL1/PIN1/LLGL2/ARHGAP35/CCR7/CCL13/NET1/CDKL5/RASAL2/CCL7/MAPRE2/RASGRP2/PTK2B/ARFGEF1/ARHGAP26/ADAP2	63
BP	GO:0043487	regulation of RNA stability	30/2619	183/18670	0.2039	0.4054	0.304	TNFRSF1B/CIRBP/PSMB9/FTO/IGF2BP3/EXOSC7/PUM2/SET/HNRNPA0/PSMC2/ROCK1/HSPB1/DCP2/PSMB6/FASTKD1/PSMC3/TNPO1/SLC11A1/PSMD8/UBB/PSMB5/MAPKAPK2/DND1/ZFP36L2/PSMD10/YBX1/TARDBP/MYD88/HNRNPD/DAZL	30
BP	GO:0007266	Rho protein signal transduction	33/2619	203/18670	0.2045	0.4063	0.3047	ECT2/ARHGEF3/CDC42EP3/SOS1/ARHGEF40/ITSN2/ARHGEF9/CDC42SE1/APOE/PECAM1/RHOF/ARHGEF2/ROCK1/ARRB1/F2R/ARHGEF7/CHUK/RAC2/RASIP1/RND2/MYOC/ARHGAP35/NET1/PHACTR4/NGFR/RAF1/AKAP13/RHOH/EPS8L2/COL3A1/GPR4/KANK2/MCF2L	33
BP	GO:0031952	regulation of protein autophosphorylation	9/2619	47/18670	0.2058	0.4064	0.3048	TOM1L1/ENPP1/NBN/PTPRC/RAP2C/PDGFB/VEGFA/RAD50/MVP	9
BP	GO:0051181	cofactor transport	9/2619	47/18670	0.2058	0.4064	0.3048	SLC22A17/FOLR1/CD320/SLC7A11/FOLR2/SLC48A1/ABCC1/LMBRD1/SLC25A11	9
BP	GO:0060048	cardiac muscle contraction	23/2619	137/18670	0.2059	0.4064	0.3048	SCN1B/ATP1B1/SNTA1/SRI/KCNQ1/STC1/BIN1/EHD3/KCNJ2/MYL3/CXCR4/TAZ/P2RX4/MYL4/CACNB2/KCNJ8/KCNN2/GAA/CACNA1D/FLNA/NEDD4L/VEGFB/PIK3CA	23
BP	GO:0009798	axis specification	15/2619	85/18670	0.2061	0.4064	0.3048	SFRP1/NOTCH1/STC1/MDFI/BMP4/C2CD3/MNS1/WLS/SIX2/CXXC4/TMED2/SIX3/ETS2/SMO/DDIT3	15
BP	GO:0072384	organelle transport along microtubule	15/2619	85/18670	0.2061	0.4064	0.3048	MREG/RASGRP1/NDE1/UCHL1/SYNE2/BLOC1S1/TRAK1/DYNC1I1/VAMP7/DYNC1H1/UBB/PEX14/SPAST/HIF1A/TRIM58	15
BP	GO:0006403	RNA localization	37/2619	230/18670	0.2069	0.4064	0.3048	CETN2/HNRNPA2B1/ATR/NXF3/NUP160/RFTN1/IGF2BP3/ATM/THOC2/NUP153/DDX39A/NHP2/THOC1/TPR/NUP50/SEC13/NMD3/RANBP2/NXF1/DCP2/KIF5C/SNUPN/SRSF4/NUP210/HNRNPA1/SFPQ/RUVBL2/NUP43/NDC1/SETD2/YTHDC1/NCBP2/EIF6/MVP/MRPL18/NUP98/NUP62	37
BP	GO:0002418	immune response to tumor cell	4/2619	17/18670	0.2075	0.4064	0.3048	PRF1/CRTAM/HMGB1/FBXO38	4
BP	GO:0006474	N-terminal protein amino acid acetylation	4/2619	17/18670	0.2075	0.4064	0.3048	NAA16/NAA50/KAT2B/EP300	4
BP	GO:0006590	thyroid hormone generation	4/2619	17/18670	0.2075	0.4064	0.3048	DIO3/MED1/CPQ/DIO2	4
BP	GO:0006595	polyamine metabolic process	4/2619	17/18670	0.2075	0.4064	0.3048	AGMAT/SMS/SRM/OAZ3	4
BP	GO:0006825	copper ion transport	4/2619	17/18670	0.2075	0.4064	0.3048	SCO2/SLC31A2/CP/CUTC	4
BP	GO:0006883	cellular sodium ion homeostasis	4/2619	17/18670	0.2075	0.4064	0.3048	C7/ATP1B1/AGT/NEDD4L	4
BP	GO:0010744	positive regulation of macrophage derived foam cell differentiation	4/2619	17/18670	0.2075	0.4064	0.3048	PRKCH/NFKB1/AGT/LPL	4
BP	GO:0014733	regulation of skeletal muscle adaptation	4/2619	17/18670	0.2075	0.4064	0.3048	IGFBP5/GTF2IRD1/PPP3CA/CAMK2B	4
BP	GO:0015732	prostaglandin transport	4/2619	17/18670	0.2075	0.4064	0.3048	ABCC4/TNFRSF11A/SLCO3A1/P2RX4	4
BP	GO:0016246	RNA interference	4/2619	17/18670	0.2075	0.4064	0.3048	ADAR/CELF1/PRKRA/TSN	4
BP	GO:0030540	female genitalia development	4/2619	17/18670	0.2075	0.4064	0.3048	RBP4/MERTK/AXL/TYRO3	4
BP	GO:0033145	positive regulation of intracellular steroid hormone receptor signaling pathway	4/2619	17/18670	0.2075	0.4064	0.3048	AR/MED1/LMO3/BUD31	4
BP	GO:0033262	regulation of nuclear cell cycle DNA replication	4/2619	17/18670	0.2075	0.4064	0.3048	CDC7/CHEK2/DBF4/ATRX	4
BP	GO:0033599	regulation of mammary gland epithelial cell proliferation	4/2619	17/18670	0.2075	0.4064	0.3048	GPX1/BRCA2/DEAF1/HOXA5	4
BP	GO:0034433	steroid esterification	4/2619	17/18670	0.2075	0.4064	0.3048	APOE/APOC1/ACAT1/AGT	4
BP	GO:0034434	sterol esterification	4/2619	17/18670	0.2075	0.4064	0.3048	APOE/APOC1/ACAT1/AGT	4
BP	GO:0034435	cholesterol esterification	4/2619	17/18670	0.2075	0.4064	0.3048	APOE/APOC1/ACAT1/AGT	4
BP	GO:0034501	protein localization to kinetochore	4/2619	17/18670	0.2075	0.4064	0.3048	NDC80/MIS12/AURKB/CDK1	4
BP	GO:0035729	cellular response to hepatocyte growth factor stimulus	4/2619	17/18670	0.2075	0.4064	0.3048	LGMN/HGF/MED1/CREB1	4
BP	GO:0035930	corticosteroid hormone secretion	4/2619	17/18670	0.2075	0.4064	0.3048	AGT/TAC1/GAL/CRY1	4
BP	GO:0035988	chondrocyte proliferation	4/2619	17/18670	0.2075	0.4064	0.3048	STC1/COMP/SIX2/HMGA2	4
BP	GO:0042953	lipoprotein transport	4/2619	17/18670	0.2075	0.4064	0.3048	PRKCB/ZDHHC17/PPARG/UNC119B	4
BP	GO:0042994	cytoplasmic sequestering of transcription factor	4/2619	17/18670	0.2075	0.4064	0.3048	NFKBIA/SRI/MDFI/PSMD10	4
BP	GO:0043968	histone H2A acetylation	4/2619	17/18670	0.2075	0.4064	0.3048	MSL3/TRRAP/RUVBL2/MORF4L1	4
BP	GO:0044872	lipoprotein localization	4/2619	17/18670	0.2075	0.4064	0.3048	PRKCB/ZDHHC17/PPARG/UNC119B	4
BP	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate	4/2619	17/18670	0.2075	0.4064	0.3048	APOBEC3C/TOP2A/CXCL8/HMGA2	4
BP	GO:0045721	negative regulation of gluconeogenesis	4/2619	17/18670	0.2075	0.4064	0.3048	SIK1/FAM3A/EP300/CRY1	4
BP	GO:0045725	positive regulation of glycogen biosynthetic process	4/2619	17/18670	0.2075	0.4064	0.3048	INSR/DYRK2/IGF1/SORBS1	4
BP	GO:0046500	S-adenosylmethionine metabolic process	4/2619	17/18670	0.2075	0.4064	0.3048	BHMT2/GAMT/PEMT/AHCY	4
BP	GO:0051969	regulation of transmission of nerve impulse	4/2619	17/18670	0.2075	0.4064	0.3048	TYMP/AGT/HCRT/GHSR	4
BP	GO:0060850	regulation of transcription involved in cell fate commitment	4/2619	17/18670	0.2075	0.4064	0.3048	RORA/PPARG/EVX1/CEBPB	4
BP	GO:0061298	retina vasculature development in camera-type eye	4/2619	17/18670	0.2075	0.4064	0.3048	ROM1/LRP5/HIF1A/COL4A1	4
BP	GO:0070131	positive regulation of mitochondrial translation	4/2619	17/18670	0.2075	0.4064	0.3048	UQCC1/RMND1/COA3/NGRN	4
BP	GO:0070525	tRNA threonylcarbamoyladenosine metabolic process	4/2619	17/18670	0.2075	0.4064	0.3048	HSD17B10/PUS1/OSGEP/TRMT5	4
BP	GO:0097329	response to antimetabolite	4/2619	17/18670	0.2075	0.4064	0.3048	DDX11/ATRX/TIMELESS/ASNS	4
BP	GO:1901524	regulation of mitophagy	4/2619	17/18670	0.2075	0.4064	0.3048	VPS13C/PINK1/OPTN/CLEC16A	4
BP	GO:1902931	negative regulation of alcohol biosynthetic process	4/2619	17/18670	0.2075	0.4064	0.3048	ERLIN2/APOE/NFKB1/SOD1	4
BP	GO:1903209	positive regulation of oxidative stress-induced cell death	4/2619	17/18670	0.2075	0.4064	0.3048	FBXW7/SFPQ/MCL1/SOD1	4
BP	GO:2000001	regulation of DNA damage checkpoint	4/2619	17/18670	0.2075	0.4064	0.3048	RFWD3/CHEK2/THOC1/CRY1	4
BP	GO:2001267	regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	4/2619	17/18670	0.2075	0.4064	0.3048	JAK2/SMAD3/FAS/NLE1	4
BP	GO:0006513	protein monoubiquitination	12/2619	66/18670	0.2083	0.4075	0.3057	SKP1/BIRC2/FBXL2/PCGF1/TRIM21/UBB/DTL/DDB2/PEX12/RYBP/RING1/NEDD4L	12
BP	GO:1901880	negative regulation of protein depolymerization	12/2619	66/18670	0.2083	0.4075	0.3057	STMN2/TMOD1/FGF13/CAPZA1/ARHGEF2/TAOK1/TMOD2/CLASP1/SCIN/KATNB1/CIB1/LIMA1	12
BP	GO:1902108	regulation of mitochondrial membrane permeability involved in apoptotic process	12/2619	66/18670	0.2083	0.4075	0.3057	EYA2/BAD/GSK3B/NOL3/GZMB/TMEM14A/PPP1R13B/YWHAH/TP53BP2/ACAA2/HIP1R/ATF2	12
BP	GO:1905710	positive regulation of membrane permeability	12/2619	66/18670	0.2083	0.4075	0.3057	EYA2/BAD/GSK3B/GZMB/TMEM14A/PPP1R13B/YWHAH/TP53BP2/ACAA2/DEFA5/HIP1R/ATF2	12
BP	GO:0019985	translesion synthesis	8/2619	41/18670	0.2093	0.4086	0.3065	POLD2/RPA1/RPA3/POLD4/UBB/DTL/UBE2L6/RFC2	8
BP	GO:0043267	negative regulation of potassium ion transport	8/2619	41/18670	0.2093	0.4086	0.3065	BIN1/ANK3/RGS4/NOS3/HCRT/PTK2B/ATF4/NEDD4L	8
BP	GO:0044091	membrane biogenesis	8/2619	41/18670	0.2093	0.4086	0.3065	CDH2/RFTN1/MAGI2/ANK3/UGCG/PEX11A/EMP2/PSAP	8
BP	GO:0045616	regulation of keratinocyte differentiation	8/2619	41/18670	0.2093	0.4086	0.3065	NOTCH1/FOXC1/NCOA3/PRKCH/MED1/ROCK1/HOXA7/REG3A	8
BP	GO:0050798	activated T cell proliferation	8/2619	41/18670	0.2093	0.4086	0.3065	BTN2A2/IGFBP2/PRNP/IGF1/SATB1/HMGB1/BTN3A1/IL6R	8
BP	GO:0090279	regulation of calcium ion import	8/2619	41/18670	0.2093	0.4086	0.3065	DYSF/EGF/PRNP/STC1/PDGFB/CALCR/TRPV2/LGALS3	8
BP	GO:0043488	regulation of mRNA stability	29/2619	177/18670	0.2096	0.4091	0.3069	CIRBP/PSMB9/FTO/IGF2BP3/EXOSC7/PUM2/SET/HNRNPA0/PSMC2/ROCK1/HSPB1/DCP2/PSMB6/FASTKD1/PSMC3/TNPO1/SLC11A1/PSMD8/UBB/PSMB5/MAPKAPK2/DND1/ZFP36L2/PSMD10/YBX1/TARDBP/MYD88/HNRNPD/DAZL	29
BP	GO:0015695	organic cation transport	7/2619	35/18670	0.212	0.4103	0.3077	TACR2/SLC22A4/SLC38A2/SLC22A18/CHRNA3/SEC14L1/OAZ3	7
BP	GO:0019076	viral release from host cell	7/2619	35/18670	0.212	0.4103	0.3077	TRIM26/PC/TRIM21/CHMP2A/PML/TRIM32/VAPA	7
BP	GO:0019433	triglyceride catabolic process	7/2619	35/18670	0.212	0.4103	0.3077	PNPLA4/LIPC/APOE/CPS1/LPL/FABP7/FABP3	7
BP	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	7/2619	35/18670	0.212	0.4103	0.3077	HFE/FHIT/OGT/RYBP/N4BP1/CLEC16A/USP14	7
BP	GO:0033144	negative regulation of intracellular steroid hormone receptor signaling pathway	7/2619	35/18670	0.212	0.4103	0.3077	SFRP1/CYP7B1/PHB/NCOR1/HDAC1/CRY1/KANK2	7
BP	GO:0035890	exit from host	7/2619	35/18670	0.212	0.4103	0.3077	TRIM26/PC/TRIM21/CHMP2A/PML/TRIM32/VAPA	7
BP	GO:0035891	exit from host cell	7/2619	35/18670	0.212	0.4103	0.3077	TRIM26/PC/TRIM21/CHMP2A/PML/TRIM32/VAPA	7
BP	GO:0046466	membrane lipid catabolic process	7/2619	35/18670	0.212	0.4103	0.3077	FUCA1/SPHK1/ASAH1/GM2A/NEU1/SGPL1/PSAP	7
BP	GO:0052126	movement in host environment	7/2619	35/18670	0.212	0.4103	0.3077	TRIM26/PC/TRIM21/CHMP2A/PML/TRIM32/VAPA	7
BP	GO:0052192	movement in environment of other organism involved in symbiotic interaction	7/2619	35/18670	0.212	0.4103	0.3077	TRIM26/PC/TRIM21/CHMP2A/PML/TRIM32/VAPA	7
BP	GO:0070873	regulation of glycogen metabolic process	7/2619	35/18670	0.212	0.4103	0.3077	ENPP1/GSK3B/INSR/DYRK2/IGF1/PASK/SORBS1	7
BP	GO:0098751	bone cell development	7/2619	35/18670	0.212	0.4103	0.3077	FBXW7/KIT/MED1/TYROBP/ABI1/EP300/SH2B3	7
BP	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	7/2619	35/18670	0.212	0.4103	0.3077	BAD/GSK3B/GZMB/PPP1R13B/YWHAH/TP53BP2/HIP1R	7
BP	GO:1901385	regulation of voltage-gated calcium channel activity	7/2619	35/18670	0.212	0.4103	0.3077	DYSF/SRI/FGF14/EHD3/S100A1/CACNB2/REM1	7
BP	GO:1990774	tumor necrosis factor secretion	7/2619	35/18670	0.212	0.4103	0.3077	IL27RA/SYT11/LILRA2/IFNG/GHSR/HMGB1/LPL	7
BP	GO:0002347	response to tumor cell	5/2619	23/18670	0.2127	0.4103	0.3077	PRF1/CRTAM/HMGB1/HNMT/FBXO38	5
BP	GO:0006359	regulation of transcription by RNA polymerase III	5/2619	23/18670	0.2127	0.4103	0.3077	CEBPA/AR/CHD8/POLR3C/BRF2	5
BP	GO:0007413	axonal fasciculation	5/2619	23/18670	0.2127	0.4103	0.3077	SEMA3A/TNFRSF21/NDN/EPHA4/ARHGAP35	5
BP	GO:0009310	amine catabolic process	5/2619	23/18670	0.2127	0.4103	0.3077	ALDH7A1/HAAO/IDO1/ATP2B4/HNMT	5
BP	GO:0009595	detection of biotic stimulus	5/2619	23/18670	0.2127	0.4103	0.3077	TREM2/CRTAM/NOD2/NOD1/SMO	5
BP	GO:0010447	response to acidic pH	5/2619	23/18670	0.2127	0.4103	0.3077	LGMN/PKD2L1/RAB11B/GPR4/SERPINF1	5
BP	GO:0032331	negative regulation of chondrocyte differentiation	5/2619	23/18670	0.2127	0.4103	0.3077	EFEMP1/SOX9/LTBP3/BMP4/GDF5	5
BP	GO:0032401	establishment of melanosome localization	5/2619	23/18670	0.2127	0.4103	0.3077	MREG/RAB27A/BBS4/DCTN2/RAB11B	5
BP	GO:0032959	inositol trisphosphate biosynthetic process	5/2619	23/18670	0.2127	0.4103	0.3077	PLCG2/GPER1/PLCE1/PLCD1/PTK2B	5
BP	GO:0034123	positive regulation of toll-like receptor signaling pathway	5/2619	23/18670	0.2127	0.4103	0.3077	PTPN22/PELI1/TLR5/MFHAS1/HMGB1	5
BP	GO:0051904	pigment granule transport	5/2619	23/18670	0.2127	0.4103	0.3077	MREG/RAB27A/BBS4/DCTN2/RAB11B	5
BP	GO:0060445	branching involved in salivary gland morphogenesis	5/2619	23/18670	0.2127	0.4103	0.3077	HGF/SEMA3A/LAMA5/PLXND1/PLXNA1	5
BP	GO:0060479	lung cell differentiation	5/2619	23/18670	0.2127	0.4103	0.3077	SOX9/RBPJ/AIMP2/HOXA5/CREB1	5
BP	GO:0072215	regulation of metanephros development	5/2619	23/18670	0.2127	0.4103	0.3077	STAT1/BMP4/MYC/EGR1/PDGFB	5
BP	GO:0089718	amino acid import across plasma membrane	5/2619	23/18670	0.2127	0.4103	0.3077	SLC7A11/RGS4/AGT/ARL6IP5/SLC1A1	5
BP	GO:0106030	neuron projection fasciculation	5/2619	23/18670	0.2127	0.4103	0.3077	SEMA3A/TNFRSF21/NDN/EPHA4/ARHGAP35	5
BP	GO:1901032	negative regulation of response to reactive oxygen species	5/2619	23/18670	0.2127	0.4103	0.3077	HGF/PINK1/TRAP1/PYCR1/PSAP	5
BP	GO:1903206	negative regulation of hydrogen peroxide-induced cell death	5/2619	23/18670	0.2127	0.4103	0.3077	HGF/PINK1/TRAP1/PYCR1/PSAP	5
BP	GO:2001039	negative regulation of cellular response to drug	5/2619	23/18670	0.2127	0.4103	0.3077	HGF/PINK1/TRAP1/PYCR1/PSAP	5
BP	GO:0007409	axonogenesis	72/2619	468/18670	0.2135	0.4103	0.3077	NOTCH1/SCN1B/TCTN1/CDH2/UST/SEMA4D/MAPK3/UNC5C/MYCBP2/MACF1/UCHL1/SEMA4A/SOS1/SEMA3A/SPG11/FGF13/TUBB2B/NEO1/NDN/BAIAP2/BSG/CHN1/NTRK2/APOE/GSK3B/GFRA1/BCL11B/MAPK7/SEMA4C/ERBB2/EFNA5/TRAK1/CYFIP2/FZD3/ANK3/CXCR4/SIPA1L1/EPHB6/NTRK1/AUTS2/GRB10/KIF5C/SEMA3F/PIK3CB/EFNB1/RAC2/RND2/ADCY1/EPHA4/VEGFA/PLXND1/ARHGAP35/PRKCQ/TSKU/SEMA3E/SPAST/USP9X/CTTN/PIK3CD/GOLGA4/NGFR/TRPV2/CREB1/CDKL5/PLXNA1/CCKAR/CYFIP1/DSCAM/SMO/MYH10/BDNF/PIK3CA	72
BP	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	6/2619	29/18670	0.2135	0.4103	0.3077	BACH1/RRM2/TYMS/ID2/NPAT/FBXO5	6
BP	GO:0000303	response to superoxide	6/2619	29/18670	0.2135	0.4103	0.3077	GCH1/FBLN5/NQO1/NOS3/SOD1/PRDX2	6
BP	GO:0003016	respiratory system process	6/2619	29/18670	0.2135	0.4103	0.3077	FTO/NDN/JAG2/GAA/HOXA5/PBX3	6
BP	GO:0007271	synaptic transmission, cholinergic	6/2619	29/18670	0.2135	0.4103	0.3077	TACR2/NQO1/APOE/CHRNA3/CHRNB1/TAC1	6
BP	GO:0016577	histone demethylation	6/2619	29/18670	0.2135	0.4103	0.3077	JARID2/KDM5A/KDM2A/KDM3A/KDM7A/JMJD6	6
BP	GO:0045980	negative regulation of nucleotide metabolic process	6/2619	29/18670	0.2135	0.4103	0.3077	NUPR1/SNCA/CBFA2T3/DDIT4/PID1/TSPO	6
BP	GO:0050855	regulation of B cell receptor signaling pathway	6/2619	29/18670	0.2135	0.4103	0.3077	PRKCB/PRKCH/PTPN22/CD81/CD19/LPXN	6
BP	GO:0070528	protein kinase C signaling	6/2619	29/18670	0.2135	0.4103	0.3077	HTR2B/WNT11/CD40/PDGFB/VEGFA/SEZ6L	6
BP	GO:0070723	response to cholesterol	6/2619	29/18670	0.2135	0.4103	0.3077	PMVK/GRAMD1C/CCR5/ABCA2/NFE2L1/SMO	6
BP	GO:2000515	negative regulation of CD4-positive, alpha-beta T cell activation	6/2619	29/18670	0.2135	0.4103	0.3077	IL4R/RUNX3/RC3H2/XCL1/TNFSF4/HMGB1	6
BP	GO:0033013	tetrapyrrole metabolic process	11/2619	60/18670	0.2136	0.4103	0.3077	CD320/FECH/BDH2/IREB2/UROD/UROS/ABCC1/TSPO/NFE2L1/LMBRD1/CPOX	11
BP	GO:0048635	negative regulation of muscle organ development	11/2619	60/18670	0.2136	0.4103	0.3077	JARID2/RBP4/BMP4/LEF1/RGS4/MAPK11/CTDP1/TBX5/LUC7L/FZD7/TWIST1	11
BP	GO:0051893	regulation of focal adhesion assembly	11/2619	60/18670	0.2136	0.4103	0.3077	SFRP1/MACF1/SMAD3/LIMCH1/EFNA5/ROCK1/KDR/MAP4K4/CLASP1/MYOC/VEGFA	11
BP	GO:0090109	regulation of cell-substrate junction assembly	11/2619	60/18670	0.2136	0.4103	0.3077	SFRP1/MACF1/SMAD3/LIMCH1/EFNA5/ROCK1/KDR/MAP4K4/CLASP1/MYOC/VEGFA	11
BP	GO:0090342	regulation of cell aging	11/2619	60/18670	0.2136	0.4103	0.3077	HLA-G/ING2/FOXM1/PLK2/NAMPT/MAP3K3/KRAS/HMGA1/HMGA2/TWIST1/FBXO5	11
BP	GO:0120193	tight junction organization	11/2619	60/18670	0.2136	0.4103	0.3077	ECT2/MICALL2/ARL2/PRKCH/PECAM1/WNT11/ROCK1/PRKCI/RAB13/MTDH/LSR	11
BP	GO:1902110	positive regulation of mitochondrial membrane permeability involved in apoptotic process	11/2619	60/18670	0.2136	0.4103	0.3077	EYA2/BAD/GSK3B/GZMB/TMEM14A/PPP1R13B/YWHAH/TP53BP2/ACAA2/HIP1R/ATF2	11
BP	GO:0060485	mesenchyme development	44/2619	278/18670	0.2144	0.4116	0.3087	SIX1/SFRP1/NOTCH1/FOLR1/STAT1/SOX9/SEMA4D/MAPK3/SMAD3/TMEM100/SEMA4A/FOXC1/MEOX1/HGF/SEMA3A/EZH2/GSK3B/BMP4/SEMA4C/HTR2B/WNT11/FAM172A/LEF1/LAMA5/FOXF1/ZFPM2/SEMA3F/NOS3/SIX2/TBX5/EFNB1/MYC/IL6/CLASP1/RBPJ/SEMA3E/PHACTR4/HIF1A/HOXA5/HAS2/ERBB4/SMO/HMGA2/TWIST1	44
BP	GO:0003205	cardiac chamber development	28/2619	171/18670	0.2155	0.4137	0.3103	NOTCH1/DHRS3/FOXC1/SOS1/RBP4/SMARCD3/RXRA/BMP4/WNT11/MED1/MYL3/SNX17/ARID1A/MAML1/FOXF1/RBM15/ZFPM2/NOS3/TBX5/RBPJ/PRDM1/PLXND1/CPE/HIF1A/ID2/SMO/MYH10/FZD2	28
BP	GO:0030048	actin filament-based movement	23/2619	138/18670	0.2163	0.415	0.3113	SCN1B/SNTA1/MYL6B/SRI/KCNQ1/TMOD1/SYNE2/STC1/BIN1/ROCK1/KCNJ2/MYL3/WIPF1/MYL4/CACNB2/KCNJ8/KCNN2/EMP2/MYH4/CACNA1D/FLNA/MYH10/NEDD4L	23
BP	GO:0043627	response to estrogen	13/2619	73/18670	0.2176	0.4173	0.313	SFRP1/TNFRSF11B/IGFBP2/IL4R/COMT/PPARG/CRHBP/TRIM24/GSTM3/CA2/GAL/EP300/ARSB	13
BP	GO:0060350	endochondral bone morphogenesis	13/2619	73/18670	0.2176	0.4173	0.313	HOXA11/SCARA3/SOX9/FOXC1/STC1/BMP4/NAB1/PEX7/COMP/FGF18/MMP13/COL6A3/MBL2	13
BP	GO:0006584	catecholamine metabolic process	10/2619	54/18670	0.2188	0.4191	0.3143	GCH1/AKR1B1/SNCA/COMT/MOXD1/HDC/INSM1/SNCAIP/SULT1A2/TH	10
BP	GO:0009712	catechol-containing compound metabolic process	10/2619	54/18670	0.2188	0.4191	0.3143	GCH1/AKR1B1/SNCA/COMT/MOXD1/HDC/INSM1/SNCAIP/SULT1A2/TH	10
BP	GO:0046164	alcohol catabolic process	10/2619	54/18670	0.2188	0.4191	0.3143	AKR1B10/SYNJ1/APOE/SORD/GK/SNX17/AKR1C3/SULT1A2/INPP5E/ALDH3B1	10
BP	GO:0061005	cell differentiation involved in kidney development	10/2619	54/18670	0.2188	0.4191	0.3143	NOTCH1/STAT1/PRKX/BMP4/MAGI2/SIX2/PDGFB/SMO/GPR4/PODXL	10
BP	GO:0097345	mitochondrial outer membrane permeabilization	10/2619	54/18670	0.2188	0.4191	0.3143	EYA2/BAD/GSK3B/GZMB/TMEM14A/PPP1R13B/YWHAH/TP53BP2/ACAA2/HIP1R	10
BP	GO:0000041	transition metal ion transport	19/2619	112/18670	0.2192	0.4191	0.3143	TFRC/ATP6V0D1/ATP2C1/IREB2/SCO2/HFE/TCIRG1/IFNG/FTL/SLC39A8/SLC31A2/SLC11A1/ATP6V0E2/CP/SLC39A14/MCOLN1/RAB11B/SFXN1/CUTC	19
BP	GO:0001938	positive regulation of endothelial cell proliferation	19/2619	112/18670	0.2192	0.4191	0.3143	DYSF/PRKD2/PGF/THBS4/ADAM17/BMP4/HTR2B/PPP1R16B/KDR/ANG/GHSR/PDGFB/VEGFA/HMGB1/SCG2/HIF1A/STAT5A/VEGFB/NRAS	19
BP	GO:0008645	hexose transmembrane transport	19/2619	112/18670	0.2192	0.4191	0.3143	SLC2A3/ENPP1/PRKCB/PID1/RTN2/INSR/OSBPL8/PEA15/SLC2A6/SLC5A3/SLC2A11/SLC2A9/GRB10/PRKCI/IGF1/SORT1/SLC2A5/SLC2A10/SORBS1	19
BP	GO:0042303	molting cycle	19/2619	112/18670	0.2192	0.4191	0.3143	NOTCH1/SOX9/IGFBP5/NIPBL/SOS1/EGFR/FZD3/LAMA5/KRT14/RBPJ/DKK4/LGR5/FERMT1/ERCC2/HDAC1/FA2H/GAL/FZD6/SMO	19
BP	GO:0042633	hair cycle	19/2619	112/18670	0.2192	0.4191	0.3143	NOTCH1/SOX9/IGFBP5/NIPBL/SOS1/EGFR/FZD3/LAMA5/KRT14/RBPJ/DKK4/LGR5/FERMT1/ERCC2/HDAC1/FA2H/GAL/FZD6/SMO	19
BP	GO:0006400	tRNA modification	15/2619	86/18670	0.2194	0.4192	0.3145	HSD17B10/METTL8/TARBP1/ELP5/PUS7/TRMT112/ELP3/PUS1/DUS4L/SEPHS1/OSGEP/TRMT5/NSUN6/THUMPD1/TRMT13	15
BP	GO:0090559	regulation of membrane permeability	15/2619	86/18670	0.2194	0.4192	0.3145	EYA2/BAD/GSK3B/NOL3/GZMB/TMEM14A/PPP1R13B/YWHAH/TP53BP2/RASIP1/ACAA2/DEFA5/TJP2/HIP1R/ATF2	15
BP	GO:0001708	cell fate specification	17/2619	99/18670	0.2198	0.4198	0.3149	SIX1/HOXA11/NOTCH1/EYA2/AR/HOXC10/SOX9/FKBP8/EVX1/SIX2/TBX5/MGA/RBPJ/OLIG2/FZD7/SMO/TENM4	17
BP	GO:0007612	learning	24/2619	145/18670	0.2204	0.421	0.3158	PTN/LGMN/GPR88/TACR2/SLC7A11/FGF13/B4GALT2/SYNJ1/COMT/NTRK2/INSR/KIT/AGT/EN1/ATP8A1/DEAF1/NRGN/HIF1A/TAC1/CREB1/VDAC3/KRAS/ACTR2/TH	24
BP	GO:0050680	negative regulation of epithelial cell proliferation	27/2619	165/18670	0.2216	0.4231	0.3173	SFRP1/NUPR1/PTN/AR/STAT1/SOX9/FBXW7/IFT52/APOE/RUNX3/BMP4/GDF5/TNMD/MED1/PPARG/KRIT1/PEX2/CDKN1C/BRCA2/EREG/MAGED1/SCG2/PTPRK/WDR13/NGFR/ATF2/SERPINF1	27
BP	GO:0042476	odontogenesis	22/2619	132/18670	0.2226	0.4247	0.3185	TNFRSF11B/FOXC1/SDC1/BSG/SERPINE1/BCL11B/HTRA1/BMP4/LEF1/LAMA5/TCIRG1/OSR2/CA2/SNX10/JAG2/HDAC1/MMP20/NF2/ID3/ATF2/SMO/TWIST1	22
BP	GO:0045995	regulation of embryonic development	22/2619	132/18670	0.2226	0.4247	0.3185	SIX1/SFRP1/NOTCH1/AR/NIPBL/TRIP12/TDG/RACGAP1/INSR/MAPK7/BMP4/FZD3/LAMA5/IGF1/CLASP1/TGIF2/IL1RN/RBM19/CDK1/FZD7/TENM4/FZD2	22
BP	GO:0048662	negative regulation of smooth muscle cell proliferation	12/2619	67/18670	0.2236	0.4265	0.3199	TNFAIP3/IGFBP5/IL15/COMT/CTNNBIP1/PPARG/GPER1/NDRG2/IFNG/TRIB1/ANG/CDKN1A	12
BP	GO:1903391	regulation of adherens junction organization	12/2619	67/18670	0.2236	0.4265	0.3199	SFRP1/MACF1/SMAD3/LIMCH1/EFNA5/ROCK1/KDR/MAP4K4/CLASP1/MYOC/VEGFA/MAPRE2	12
BP	GO:0006111	regulation of gluconeogenesis	9/2619	48/18670	0.224	0.4268	0.3201	SIK1/PDK2/RANBP2/FAM3A/PTPN2/OGT/KAT2B/EP300/CRY1	9
BP	GO:0045933	positive regulation of muscle contraction	9/2619	48/18670	0.224	0.4268	0.3201	SPHK1/TACR2/KCNQ1/ADA/KIT/GPER1/F2R/GHSR/CTTN	9
BP	GO:0072666	establishment of protein localization to vacuole	9/2619	48/18670	0.224	0.4268	0.3201	TNFAIP3/VPS13C/CLU/VPS37C/ZFYVE16/GNPTAB/VTI1B/VAMP7/AP4M1	9
BP	GO:0001678	cellular glucose homeostasis	25/2619	152/18670	0.2243	0.4273	0.3205	FIS1/SRI/MPC2/BAD/EFNA5/CMA1/GPER1/ARRB1/OXCT1/POLG/PTPRN2/LRP5/MAP4K4/PCK2/ANO1/PPP3CA/HIF1A/PRKAA1/NGFR/RAF1/RAB11B/XBP1/SERPINF1/TH/PIK3CA	25
BP	GO:0003300	cardiac muscle hypertrophy	18/2619	106/18670	0.2257	0.4295	0.3221	NOTCH1/JARID2/TNFRSF1B/SMAD3/EZH2/HTR2B/ROCK1/RGS4/AGT/CTDP1/IGF1/SORBS2/PIN1/P2RX4/PPP3CA/ATP2B4/AKAP13/CDK9	18
BP	GO:1901989	positive regulation of cell cycle phase transition	18/2619	106/18670	0.2257	0.4295	0.3221	CDC25B/CDC7/EZH2/ADAM17/DLGAP5/EGFR/SMARCD3/CDK4/CCNB1/ZNF16/RAD51C/DTL/CDK1/CCND2/HSPA2/RAD51B/MEPCE/FBXO5	18
BP	GO:0002088	lens development in camera-type eye	14/2619	80/18670	0.2258	0.4295	0.3221	CRYBB1/WNT5B/SMAD3/TMOD1/SLC7A11/CRYBG3/CDK4/BMP4/MED1/CRYAB/CDKN1C/NF2/SIX3/MAF	14
BP	GO:0070509	calcium ion import	14/2619	80/18670	0.2258	0.4295	0.3221	DYSF/EGF/PRNP/STC1/FAM155A/PDGFB/CALCR/MICU1/CACNB2/ATP2B4/CACNA1D/TRPV2/LGALS3/MS4A1	14
BP	GO:0043687	post-translational protein modification	56/2619	361/18670	0.2261	0.4301	0.3226	CDH2/SOCS6/IGFBP5/FBXW7/SKP1/KLHL2/COPS6/SERPINA1/PSMB9/APOL1/COPS7A/AGTPBP1/APOE/APLP2/IGFBP4/RCN1/COPS8/BMP4/PENK/FBXO17/LCMT1/FBXW12/PSMC2/KLHL3/CRTAP/PSMB6/WDTC1/DCAF6/MBTPS1/MXRA8/RAB13/FN3KRP/UBE2M/PSMC3/IL6/CHRDL1/PSMD8/UCHL3/DTL/PSMB5/SCG2/CP/DDB2/DNAJC3/PSMD10/HIF1A/RAB11B/TIMP1/VCAN/ATG12/CUL2/NUCB1/NEDD8/STC2/CISH/DCUN1D1	56
BP	GO:0035304	regulation of protein dephosphorylation	23/2619	139/18670	0.2269	0.4313	0.3235	PTN/JAK2/CAMTA1/LILRB2/PTPRC/PINK1/GSK3B/PPP6R3/SET/MAGI2/ROCK1/SHOC2/PPP4R1/PPP1R16B/CDH5/PPP1R12A/MFHAS1/PIN1/ANKLE2/PHACTR4/ENSA/LGALS3/STYXL1	23
BP	GO:0007179	transforming growth factor beta receptor signaling pathway	32/2619	199/18670	0.2276	0.4313	0.3235	FOLR1/SMAD3/GOT1/MTMR4/ADAM17/LTBP3/TRIM33/HTRA1/ING2/GDF5/ADAMTSL2/RNF111/ZNF451/HPGD/FERMT2/CDH5/CDKN1C/PML/PIN1/FUT8/UBB/FERMT1/NLK/PTPRK/LTBP4/USP9X/GDF9/ITGB5/CREB1/EP300/COL3A1/HSPA5	32
BP	GO:0061013	regulation of mRNA catabolic process	32/2619	199/18670	0.2276	0.4313	0.3235	CIRBP/PSMB9/FTO/IGF2BP3/EXOSC7/PUM2/SET/HNRNPA0/ZC3HAV1/PSMC2/ROCK1/HSPB1/PRR5L/DCP2/PSMB6/FASTKD1/PSMC3/TNPO1/POLR2G/SLC11A1/PSMD8/UBB/PSMB5/MAPKAPK2/DND1/ZFP36L2/PSMD10/YBX1/TARDBP/MYD88/HNRNPD/DAZL	32
BP	GO:0006611	protein export from nucleus	29/2619	179/18670	0.2281	0.4313	0.3235	HNRNPA2B1/NXF3/NUP160/THOC2/BARD1/NUP153/XPO6/DDX39A/THOC1/GSK3B/TPR/NUP50/SEC13/NMD3/RANBP2/NXF1/SRSF4/NUP210/CAMK1/NUP43/NDC1/SETD2/GTSE1/YTHDC1/TCF7L2/NCBP2/EIF6/NUP98/NUP62	29
BP	GO:0008064	regulation of actin polymerization or depolymerization	29/2619	179/18670	0.2281	0.4313	0.3235	IQGAP2/ACTR3B/ARPC1A/TMOD1/CDC42EP3/FCHSD2/PFN2/BAIAP2/NCK2/ACTR3/CAPZA1/BIN1/BBS4/TMOD2/FHOD3/MAGEL2/SCIN/ARHGAP35/CCR7/AP1AR/TMSB10/ARPC5L/CTTN/HIP1R/CYFIP1/LIMA1/PTK2B/ARFGEF1/ACTR2	29
BP	GO:0006654	phosphatidic acid biosynthetic process	8/2619	42/18670	0.2291	0.4313	0.3235	AGPAT1/PLA2G2D/AGPAT5/DGKA/PLD1/DGKZ/ACP6/LPCAT4	8
BP	GO:1901031	regulation of response to reactive oxygen species	8/2619	42/18670	0.2291	0.4313	0.3235	GCH1/FBLN5/HGF/PINK1/TRAP1/PYCR1/SESN1/PSAP	8
BP	GO:1903146	regulation of autophagy of mitochondrion	8/2619	42/18670	0.2291	0.4313	0.3235	FBXW7/VPS13C/PINK1/TSPO/OPTN/HIF1A/CTTN/CLEC16A	8
BP	GO:2001222	regulation of neuron migration	8/2619	42/18670	0.2291	0.4313	0.3235	NIPBL/SEMA3A/ARHGEF2/ERBB4/COL3A1/FLNA/CAMK2B/LRIG2	8
BP	GO:0045604	regulation of epidermal cell differentiation	11/2619	61/18670	0.2299	0.4313	0.3235	NOTCH1/FOXC1/NCOA3/EZH2/PRKCH/BMP4/MED1/ROCK1/MAFF/HOXA7/REG3A	11
BP	GO:0046513	ceramide biosynthetic process	11/2619	61/18670	0.2299	0.4313	0.3235	SPHK1/CERS6/ASAH1/CERS4/UGCG/CERS2/SGMS1/PRKAA1/FA2H/ST8SIA2/B4GALT3	11
BP	GO:0048645	animal organ formation	11/2619	61/18670	0.2299	0.4313	0.3235	SIX1/HOXA11/FOLR1/AR/MAPK3/SMARCD3/PIM1/BMP4/TBX5/RBPJ/HOXC11	11
BP	GO:1905953	negative regulation of lipid localization	11/2619	61/18670	0.2299	0.4313	0.3235	NFKBIA/EGF/OSBPL8/PPARG/PTPN2/NFKB1/APOC1/NR1H2/IL6/PLA2R1/CRY1	11
BP	GO:0002002	regulation of angiotensin levels in blood	3/2619	12/18670	0.2312	0.4313	0.3235	CPA3/CMA1/CTSG	3
BP	GO:0002003	angiotensin maturation	3/2619	12/18670	0.2312	0.4313	0.3235	CPA3/CMA1/CTSG	3
BP	GO:0002903	negative regulation of B cell apoptotic process	3/2619	12/18670	0.2312	0.4313	0.3235	ADA/AURKB/BCL10	3
BP	GO:0002921	negative regulation of humoral immune response	3/2619	12/18670	0.2312	0.4313	0.3235	CR1/C4BPB/CD59	3
BP	GO:0003207	cardiac chamber formation	3/2619	12/18670	0.2312	0.4313	0.3235	NOTCH1/SMARCD3/TBX5	3
BP	GO:0006264	mitochondrial DNA replication	3/2619	12/18670	0.2312	0.4313	0.3235	DNA2/POLG/STOML2	3
BP	GO:0007320	insemination	3/2619	12/18670	0.2312	0.4313	0.3235	DDO/KLK14/TAC1	3
BP	GO:0009886	post-embryonic animal morphogenesis	3/2619	12/18670	0.2312	0.4313	0.3235	EFEMP1/ATRX/DSCAM	3
BP	GO:0010452	histone H3-K36 methylation	3/2619	12/18670	0.2312	0.4313	0.3235	SETMAR/SMYD2/SETD2	3
BP	GO:0010623	programmed cell death involved in cell development	3/2619	12/18670	0.2312	0.4313	0.3235	DNASE1L3/KIT/NTRK1	3
BP	GO:0010826	negative regulation of centrosome duplication	3/2619	12/18670	0.2312	0.4313	0.3235	MDM1/CHMP2A/KAT2B	3
BP	GO:0010889	regulation of sequestering of triglyceride	3/2619	12/18670	0.2312	0.4313	0.3235	OSBPL8/PPARG/LPL	3
BP	GO:0019374	galactolipid metabolic process	3/2619	12/18670	0.2312	0.4313	0.3235	FA2H/PSAP/B4GALT3	3
BP	GO:0030208	dermatan sulfate biosynthetic process	3/2619	12/18670	0.2312	0.4313	0.3235	UST/VCAN/CHST12	3
BP	GO:0030950	establishment or maintenance of actin cytoskeleton polarity	3/2619	12/18670	0.2312	0.4313	0.3235	RHOF/RND2/ARHGAP35	3
BP	GO:0032429	regulation of phospholipase A2 activity	3/2619	12/18670	0.2312	0.4313	0.3235	EGFR/ANG/PLA2R1	3
BP	GO:0033197	response to vitamin E	3/2619	12/18670	0.2312	0.4313	0.3235	ADA/PPARG/CAT	3
BP	GO:0034086	maintenance of sister chromatid cohesion	3/2619	12/18670	0.2312	0.4313	0.3235	NIPBL/SMC5/ATRX	3
BP	GO:0034088	maintenance of mitotic sister chromatid cohesion	3/2619	12/18670	0.2312	0.4313	0.3235	NIPBL/SMC5/ATRX	3
BP	GO:0034372	very-low-density lipoprotein particle remodeling	3/2619	12/18670	0.2312	0.4313	0.3235	LIPC/APOE/LPL	3
BP	GO:0035330	regulation of hippo signaling	3/2619	12/18670	0.2312	0.4313	0.3235	WWC3/NF2/MARK3	3
BP	GO:0035437	maintenance of protein localization in endoplasmic reticulum	3/2619	12/18670	0.2312	0.4313	0.3235	GPAA1/KDELR3/HSPA5	3
BP	GO:0042416	dopamine biosynthetic process	3/2619	12/18670	0.2312	0.4313	0.3235	GCH1/SNCA/TH	3
BP	GO:0043696	dedifferentiation	3/2619	12/18670	0.2312	0.4313	0.3235	NCOA3/PDGFB/HNRNPD	3
BP	GO:0043697	cell dedifferentiation	3/2619	12/18670	0.2312	0.4313	0.3235	NCOA3/PDGFB/HNRNPD	3
BP	GO:0045416	positive regulation of interleukin-8 biosynthetic process	3/2619	12/18670	0.2312	0.4313	0.3235	ELANE/BCL10/TLR8	3
BP	GO:0045472	response to ether	3/2619	12/18670	0.2312	0.4313	0.3235	CDK4/HNRNPD/TH	3
BP	GO:0045579	positive regulation of B cell differentiation	3/2619	12/18670	0.2312	0.4313	0.3235	BAD/CD27/XBP1	3
BP	GO:0048934	peripheral nervous system neuron differentiation	3/2619	12/18670	0.2312	0.4313	0.3235	NTRK2/RUNX3/HOXD9	3
BP	GO:0048935	peripheral nervous system neuron development	3/2619	12/18670	0.2312	0.4313	0.3235	NTRK2/RUNX3/HOXD9	3
BP	GO:0051657	maintenance of organelle location	3/2619	12/18670	0.2312	0.4313	0.3235	ASPM/UVRAG/AKAP9	3
BP	GO:0051956	negative regulation of amino acid transport	3/2619	12/18670	0.2312	0.4313	0.3235	HRH3/RGS4/ARL6IP5	3
BP	GO:0060442	branching involved in prostate gland morphogenesis	3/2619	12/18670	0.2312	0.4313	0.3235	SFRP1/RXRA/BMP4	3
BP	GO:0060788	ectodermal placode formation	3/2619	12/18670	0.2312	0.4313	0.3235	SIX1/DKK4/HDAC1	3
BP	GO:0070243	regulation of thymocyte apoptotic process	3/2619	12/18670	0.2312	0.4313	0.3235	ADA/BMP4/HIF1A	3
BP	GO:0071472	cellular response to salt stress	3/2619	12/18670	0.2312	0.4313	0.3235	AKR1B1/MICU1/LETM1	3
BP	GO:0071679	commissural neuron axon guidance	3/2619	12/18670	0.2312	0.4313	0.3235	FZD3/VEGFA/SMO	3
BP	GO:0071697	ectodermal placode morphogenesis	3/2619	12/18670	0.2312	0.4313	0.3235	SIX1/DKK4/HDAC1	3
BP	GO:0072540	T-helper 17 cell lineage commitment	3/2619	12/18670	0.2312	0.4313	0.3235	LY9/IL6/BATF	3
BP	GO:0072710	response to hydroxyurea	3/2619	12/18670	0.2312	0.4313	0.3235	DDX11/ATRX/TIMELESS	3
BP	GO:0090085	regulation of protein deubiquitination	3/2619	12/18670	0.2312	0.4313	0.3235	TNIP1/SART3/TRIM21	3
BP	GO:0090161	Golgi ribbon formation	3/2619	12/18670	0.2312	0.4313	0.3235	PRMT5/OPTN/GOLPH3	3
BP	GO:0090209	negative regulation of triglyceride metabolic process	3/2619	12/18670	0.2312	0.4313	0.3235	SIK1/FBXW7/APOE	3
BP	GO:0098789	pre-mRNA cleavage required for polyadenylation	3/2619	12/18670	0.2312	0.4313	0.3235	CPSF7/NCBP2/CSTF2	3
BP	GO:0099640	axo-dendritic protein transport	3/2619	12/18670	0.2312	0.4313	0.3235	HSPB1/KIF5C/SFPQ	3
BP	GO:1901298	regulation of hydrogen peroxide-mediated programmed cell death	3/2619	12/18670	0.2312	0.4313	0.3235	HGF/PINK1/TRAP1	3
BP	GO:1902337	regulation of apoptotic process involved in morphogenesis	3/2619	12/18670	0.2312	0.4313	0.3235	NOTCH1/TNFRSF1B/FOXC1	3
BP	GO:1903909	regulation of receptor clustering	3/2619	12/18670	0.2312	0.4313	0.3235	PTN/SLC7A11/CD81	3
BP	GO:1904424	regulation of GTP binding	3/2619	12/18670	0.2312	0.4313	0.3235	ARHGEF7/EPHA4/CSNK1A1	3
BP	GO:1905244	regulation of modification of synaptic structure	3/2619	12/18670	0.2312	0.4313	0.3235	BAIAP2/EPHA4/CYFIP1	3
BP	GO:2001053	regulation of mesenchymal cell apoptotic process	3/2619	12/18670	0.2312	0.4313	0.3235	SOX9/GDF5/HIF1A	3
BP	GO:0032418	lysosome localization	13/2619	74/18670	0.2324	0.4331	0.3248	RASGRP1/IL4R/S100A13/KIT/BLOC1S1/FGR/FOXF1/RAC2/VAMP7/KXD1/LAT/PIK3CD/IL13RA2	13
BP	GO:0043507	positive regulation of JUN kinase activity	13/2619	74/18670	0.2324	0.4331	0.3248	MAP3K5/RIPK2/TNIK/MAP3K11/TNFRSF11A/BIRC7/MAP4K1/DAXX/TAOK1/EPHA4/TAOK3/PTK2B/CD40LG	13
BP	GO:1900182	positive regulation of protein localization to nucleus	13/2619	74/18670	0.2324	0.4331	0.3248	ZIC1/ECT2/SMAD3/TPR/NMD3/IFNG/TARDBP/NGFR/GTSE1/CDK1/FLNA/UBR5/SMO	13
BP	GO:0010657	muscle cell apoptotic process	17/2619	100/18670	0.2325	0.4331	0.3248	NUPR1/MAP3K5/JAK2/CFLAR/DNMT1/PDE1A/HSPB6/NOL3/PPARG/ARRB1/IFNG/APAF1/AGT/IGF1/CXCR2/PTK2B/ATF4	17
BP	GO:0060840	artery development	17/2619	100/18670	0.2325	0.4331	0.3248	SIX1/NOTCH1/FOLR1/FOXC1/APOE/BMP4/WNT11/HPGD/SNX17/FOXF1/COMP/RBPJ/PRDM1/VEGFA/PLXND1/COL3A1/MYH10	17
BP	GO:0010573	vascular endothelial growth factor production	7/2619	36/18670	0.2337	0.4346	0.326	RORA/NDRG2/IL6/ADAMTS3/HIF1A/CCR2/ATF4	7
BP	GO:0032205	negative regulation of telomere maintenance	7/2619	36/18670	0.2337	0.4346	0.326	ERCC1/NBN/TNKS2/ATM/DCP2/HNRNPA1/RAD50	7
BP	GO:0033572	transferrin transport	7/2619	36/18670	0.2337	0.4346	0.326	TFRC/ATP6V0D1/HFE/TCIRG1/ATP6V0E2/MCOLN1/RAB11B	7
BP	GO:0034390	smooth muscle cell apoptotic process	7/2619	36/18670	0.2337	0.4346	0.326	DNMT1/PDE1A/PPARG/ARRB1/IFNG/IGF1/ATF4	7
BP	GO:0034391	regulation of smooth muscle cell apoptotic process	7/2619	36/18670	0.2337	0.4346	0.326	DNMT1/PDE1A/PPARG/ARRB1/IFNG/IGF1/ATF4	7
BP	GO:0071709	membrane assembly	7/2619	36/18670	0.2337	0.4346	0.326	CDH2/RFTN1/MAGI2/ANK3/UGCG/EMP2/PSAP	7
BP	GO:0003018	vascular process in circulatory system	28/2619	173/18670	0.2346	0.4361	0.3271	GCH1/TACR2/ANGPT1/DDAH1/EPHX2/CD38/FOXC1/EGFR/CTNNBIP1/APOE/HTR2B/ROCK1/GPX1/GPER1/F2R/ADRB2/CDH5/AGT/COMP/NOS3/CPS1/VEGFA/ARHGAP35/CXCR2/SOD1/HBB/KCNMB2/ATP2B1	28
BP	GO:0010469	regulation of signaling receptor activity	28/2619	173/18670	0.2346	0.4361	0.3271	FBXW7/LRPAP1/NCOA3/ADAM17/NETO2/EGF/NCK2/PINK1/SERPINE1/HFE/MED1/KLHL24/GRIA2/CHMP6/ADRB2/CBLB/IFNG/CRHBP/LDOC1/EREG/BUD31/DKK4/HMGB1/CALCR/AKAP9/PTK2B/CCR2/NCF1	28
BP	GO:0001541	ovarian follicle development	10/2619	55/18670	0.2363	0.4385	0.3289	FOXC1/ATM/KIT/ARRB1/ANG/EREG/VEGFA/SOD1/INHBB/CEBPB	10
BP	GO:0006383	transcription by RNA polymerase III	10/2619	55/18670	0.2363	0.4385	0.3289	CEBPA/AR/CHD8/POLR2L/POLR3C/BRF2/POLR2E/POLR2F/POLR1C/GTF3C5	10
BP	GO:0046456	icosanoid biosynthetic process	10/2619	55/18670	0.2363	0.4385	0.3289	HPGDS/LTC4S/PTGS1/TBXAS1/ALOX5AP/MGST3/HPGD/AKR1C3/PTGDS/CBR1	10
BP	GO:0070830	bicellular tight junction assembly	10/2619	55/18670	0.2363	0.4385	0.3289	ECT2/MICALL2/ARL2/PRKCH/PECAM1/WNT11/ROCK1/PRKCI/RAB13/MTDH	10
BP	GO:2000242	negative regulation of reproductive process	10/2619	55/18670	0.2363	0.4385	0.3289	HPGDS/ADA/BMP4/NPR2/ZFPM2/IGF1/RAD1/TIMP1/SERPINF1/FBXO5	10
BP	GO:0000002	mitochondrial genome maintenance	6/2619	30/18670	0.2376	0.4398	0.3299	SLC25A4/DNA2/TYMP/POLG/MPV17/STOML2	6
BP	GO:0000027	ribosomal large subunit assembly	6/2619	30/18670	0.2376	0.4398	0.3299	NLE1/RPL12/MRPL11/MDN1/MRPL20/RPLP0	6
BP	GO:0006517	protein deglycosylation	6/2619	30/18670	0.2376	0.4398	0.3299	MAN2B2/MAN1C1/NGLY1/MAN1B1/EDEM1/SEL1L	6
BP	GO:0035066	positive regulation of histone acetylation	6/2619	30/18670	0.2376	0.4398	0.3299	MAPK3/NAP1L2/ARRB1/AUTS2/RUVBL2/PIWIL2	6
BP	GO:0042759	long-chain fatty acid biosynthetic process	6/2619	30/18670	0.2376	0.4398	0.3299	LTC4S/EPHX2/GSTM4/HPGD/GPX4/PLP1	6
BP	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	6/2619	30/18670	0.2376	0.4398	0.3299	RASGRP1/HLA-F/MICB/HLA-E/CRTAM/ULBP2	6
BP	GO:0048384	retinoic acid receptor signaling pathway	6/2619	30/18670	0.2376	0.4398	0.3299	DHRS3/EZH2/PRAME/RXRA/AKR1C3/PML	6
BP	GO:0061037	negative regulation of cartilage development	6/2619	30/18670	0.2376	0.4398	0.3299	EFEMP1/SOX9/LTBP3/BMP4/GDF5/WNT11	6
BP	GO:0030832	regulation of actin filament length	29/2619	180/18670	0.2377	0.4398	0.3299	IQGAP2/ACTR3B/ARPC1A/TMOD1/CDC42EP3/FCHSD2/PFN2/BAIAP2/NCK2/ACTR3/CAPZA1/BIN1/BBS4/TMOD2/FHOD3/MAGEL2/SCIN/ARHGAP35/CCR7/AP1AR/TMSB10/ARPC5L/CTTN/HIP1R/CYFIP1/LIMA1/PTK2B/ARFGEF1/ACTR2	29
BP	GO:0035023	regulation of Rho protein signal transduction	23/2619	140/18670	0.2377	0.4398	0.3299	ECT2/ARHGEF3/SOS1/ARHGEF40/ITSN2/ARHGEF9/CDC42SE1/APOE/ARHGEF2/ARRB1/F2R/ARHGEF7/RASIP1/MYOC/ARHGAP35/NET1/RAF1/AKAP13/EPS8L2/COL3A1/GPR4/KANK2/MCF2L	23
BP	GO:0050905	neuromuscular process	18/2619	107/18670	0.2381	0.4403	0.3302	GCH1/HOXC10/GPR88/MYCBP2/CHD8/NBN/UCHL1/CAMTA1/AGTPBP1/PENK/HERC1/COMP/GM2A/ALDH1A3/GAA/FABP7/PSAP/MYH10	18
BP	GO:0062014	negative regulation of small molecule metabolic process	18/2619	107/18670	0.2381	0.4403	0.3302	SIK1/NUPR1/SNCA/ERLIN2/CBFA2T3/DDIT4/PID1/APOE/FAM3A/NFKB1/APOC1/WDTC1/TSPO/AKR1C3/SOD1/ATP2B4/EP300/CRY1	18
BP	GO:0021756	striatum development	4/2619	18/18670	0.2392	0.4403	0.3302	SLC7A11/BCL11B/BBS4/ALDH1A3	4
BP	GO:0030809	negative regulation of nucleotide biosynthetic process	4/2619	18/18670	0.2392	0.4403	0.3302	NUPR1/CBFA2T3/DDIT4/PID1	4
BP	GO:0031468	nuclear envelope reassembly	4/2619	18/18670	0.2392	0.4403	0.3302	BANF1/CHMP2A/ANKLE2/SPAST	4
BP	GO:0039692	single stranded viral RNA replication via double stranded DNA intermediate	4/2619	18/18670	0.2392	0.4403	0.3302	APOBEC3C/TOP2A/CXCL8/HMGA2	4
BP	GO:0043555	regulation of translation in response to stress	4/2619	18/18670	0.2392	0.4403	0.3302	NCK2/DNAJC3/RPS6KA1/ATF4	4
BP	GO:0046459	short-chain fatty acid metabolic process	4/2619	18/18670	0.2392	0.4403	0.3302	THNSL2/PHYH/PCCB/PCK2	4
BP	GO:0048339	paraxial mesoderm development	4/2619	18/18670	0.2392	0.4403	0.3302	SMAD3/FOXC1/WNT11/LEF1	4
BP	GO:0048739	cardiac muscle fiber development	4/2619	18/18670	0.2392	0.4403	0.3302	MYOM2/BMP4/VEGFA/CXADR	4
BP	GO:0051782	negative regulation of cell division	4/2619	18/18670	0.2392	0.4403	0.3302	ASPM/ORC6/MYC/AURKB	4
BP	GO:0060977	coronary vasculature morphogenesis	4/2619	18/18670	0.2392	0.4403	0.3302	NOTCH1/TBX5/VEGFA/SETD2	4
BP	GO:0070875	positive regulation of glycogen metabolic process	4/2619	18/18670	0.2392	0.4403	0.3302	INSR/DYRK2/IGF1/SORBS1	4
BP	GO:1900372	negative regulation of purine nucleotide biosynthetic process	4/2619	18/18670	0.2392	0.4403	0.3302	NUPR1/CBFA2T3/DDIT4/PID1	4
BP	GO:1902165	regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	4/2619	18/18670	0.2392	0.4403	0.3302	ING2/HNRNPK/CD44/TAF9B	4
BP	GO:1903019	negative regulation of glycoprotein metabolic process	4/2619	18/18670	0.2392	0.4403	0.3302	TMEM59/HBEGF/ITM2C/ACOT8	4
BP	GO:2000193	positive regulation of fatty acid transport	4/2619	18/18670	0.2392	0.4403	0.3302	TNFRSF11A/P2RX4/PLA2R1/FABP3	4
BP	GO:0002861	regulation of inflammatory response to antigenic stimulus	5/2619	24/18670	0.24	0.4403	0.3302	HLA-E/CD28/GPX1/CD81/CCR7	5
BP	GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway	5/2619	24/18670	0.24	0.4403	0.3302	SNCA/PTPN2/CBLB/HIP1R/LRIG2	5
BP	GO:0018126	protein hydroxylation	5/2619	24/18670	0.24	0.4403	0.3302	P4HTM/ASPH/JMJD6/CRTAP/EGLN3	5
BP	GO:0032528	microvillus organization	5/2619	24/18670	0.24	0.4403	0.3302	TNIK/ATP8B1/PLD1/RAPGEF6/PODXL	5
BP	GO:0042537	benzene-containing compound metabolic process	5/2619	24/18670	0.24	0.4403	0.3302	HAAO/IDO1/GSTM4/GSTM3/TH	5
BP	GO:0044062	regulation of excretion	5/2619	24/18670	0.24	0.4403	0.3302	COMT/STC1/AGT/TAC1/CORIN	5
BP	GO:0044346	fibroblast apoptotic process	5/2619	24/18670	0.24	0.4403	0.3302	SFRP1/CHD8/STK17B/MYC/PIK3CA	5
BP	GO:0046426	negative regulation of JAK-STAT cascade	5/2619	24/18670	0.24	0.4403	0.3302	SOCS1/PTPN2/NF2/GGNBP2/SH2B3	5
BP	GO:0051220	cytoplasmic sequestering of protein	5/2619	24/18670	0.24	0.4403	0.3302	NFKBIA/SRI/MDFI/PSMD10/FLNA	5
BP	GO:0051446	positive regulation of meiotic cell cycle	5/2619	24/18670	0.24	0.4403	0.3302	CDC25B/INSR/YTHDC2/PIWIL2/DAZL	5
BP	GO:0051905	establishment of pigment granule localization	5/2619	24/18670	0.24	0.4403	0.3302	MREG/RAB27A/BBS4/DCTN2/RAB11B	5
BP	GO:1903020	positive regulation of glycoprotein metabolic process	5/2619	24/18670	0.24	0.4403	0.3302	IL15/IGF1/CCR7/TCF7L2/ARFGEF1	5
BP	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	14/2619	81/18670	0.2402	0.4404	0.3303	CEBPA/CLU/HERPUD1/CBFA2T3/GSK3B/CHFR/PLK2/TRIB1/DET1/CSNK1A1/RNF19B/CSNK1E/PSMD10/RNF14	14
BP	GO:1903533	regulation of protein targeting	14/2619	81/18670	0.2402	0.4404	0.3303	FIS1/FBXW7/MICALL2/PRNP/PINK1/ERBB2/ANK3/RAC2/VAMP7/ATG13/PRKAA1/CIB1/NUCB1/UBL5	14
BP	GO:0035270	endocrine system development	21/2619	127/18670	0.2406	0.4411	0.3308	PITX1/SIX1/SOX9/MAPK3/SMAD3/BAD/GSK3B/INSR/BMP4/WNT11/TSPO/INSM1/IL6/CDKN1C/RBPJ/HOXA5/SIX3/RAF1/IL6R/CREB1/SMO	21
BP	GO:0032535	regulation of cellular component size	57/2619	370/18670	0.2407	0.4411	0.3308	IQGAP2/ACTR3B/SEMA4D/ARPC1A/SLC12A8/MACF1/TMOD1/IL7R/SEMA4A/CDC42EP3/SEMA3A/FGF13/DEPTOR/FCHSD2/PFN2/BAIAP2/NCK2/SLC12A7/ACTR3/APOE/GSK3B/CDK4/AP2M1/CAPZA1/BIN1/SEMA4C/EFNA5/BBS4/PEX11A/WDTC1/SEMA3F/TMOD2/RND2/FHOD3/MAGEL2/VEGFA/SCIN/ARHGAP35/CCR7/AP1AR/SEMA3E/TMSB10/ARPC5L/ANXA7/CTTN/GOLGA4/TRPV2/CREB1/CDKL5/HIP1R/CYFIP1/LIMA1/PTK2B/DSCAM/ARFGEF1/ACTR2/BDNF	57
BP	GO:0035094	response to nicotine	9/2619	49/18670	0.2428	0.4446	0.3335	SLC7A11/BAD/PENK/NFKB1/NTRK1/CHRNA3/CHRNB1/CREB1/TH	9
BP	GO:0060042	retina morphogenesis in camera-type eye	9/2619	49/18670	0.2428	0.4446	0.3335	PTN/DIO3/SOX9/RBP4/ROM1/LRP5/RS1/IRX5/DSCAM	9
BP	GO:1904707	positive regulation of vascular smooth muscle cell proliferation	9/2619	49/18670	0.2428	0.4446	0.3335	MAP3K5/JAK2/IGFBP5/DNMT1/HPGD/AGT/IGF1/PDGFB/FOXJ2	9
BP	GO:0015749	monosaccharide transmembrane transport	19/2619	114/18670	0.2433	0.4451	0.3339	SLC2A3/ENPP1/PRKCB/PID1/RTN2/INSR/OSBPL8/PEA15/SLC2A6/SLC5A3/SLC2A11/SLC2A9/GRB10/PRKCI/IGF1/SORT1/SLC2A5/SLC2A10/SORBS1	19
BP	GO:0060349	bone morphogenesis	19/2619	114/18670	0.2433	0.4451	0.3339	HOXA11/SCARA3/SOX9/DHRS3/FOXC1/LTBP3/STC1/BMP4/NAB1/PEX7/OSR2/LRP5/COMP/FGF18/MMP13/COL6A3/MBL2/HAS2/TWIST1	19
BP	GO:0018210	peptidyl-threonine modification	22/2619	134/18670	0.2448	0.4479	0.3359	SPHK1/CDC7/GALNT11/PRKD2/RIPK2/TBK1/PRKCB/DDIT4/CHEK1/DYRK4/EGF/GSK3B/DYRK2/CSNK2B/ROCK1/VRK2/CSNK1A1/GALNT3/CSNK1E/NLK/CDK1/CLK1	22
BP	GO:0022412	cellular process involved in reproduction in multicellular organism	55/2619	357/18670	0.2452	0.4484	0.3363	CDC25B/SFRP1/PTN/SRPK1/ERCC1/ASPM/MYBL1/FOXC1/UBR2/SOS1/SERPINA5/ATM/NME5/UBE2J1/ANGPT2/KIT/ING2/BMP4/CELF1/KDM3A/BBS4/TTLL1/NCAPH/DPY19L2P2/ARRB1/FOLR2/DIAPH2/NPR2/DLD/IGF1/CCNB1/ETV6/ANG/BRCA2/EREG/PRDM1/DEAF1/UBB/RAD51C/LGR5/YTHDC2/TOP2A/DND1/TMF1/CIB1/GDF9/DAZAP1/CXADR/HSPA2/PIWIL2/INHBB/PTK2B/ABHD2/DAZL/FBXO5	55
BP	GO:0050830	defense response to Gram-positive bacterium	17/2619	101/18670	0.2455	0.4488	0.3366	GBP2/IL27RA/RIPK2/TBK1/ADAM17/TNFRSF14/HLA-E/FGR/IL6/DEFA6/TNFSF8/MBL2/GSDMD/NOD1/CTSG/DEFA5/MYD88	17
BP	GO:0009880	embryonic pattern specification	11/2619	62/18670	0.2467	0.4504	0.3378	SMAD3/MEOX1/SEMA3A/C2CD3/SEMA3F/EFNB1/CXXC4/TMED2/SIM2/ERBB4/SATB2	11
BP	GO:0010676	positive regulation of cellular carbohydrate metabolic process	11/2619	62/18670	0.2467	0.4504	0.3378	SNCA/PTH1R/BAD/INSR/DYRK2/RANBP2/GPER1/PTPN2/IGF1/KAT2B/SORBS1	11
BP	GO:0048857	neural nucleus development	11/2619	62/18670	0.2467	0.4504	0.3378	ZNF430/YWHAH/NDRG2/S100A1/SEC16A/ALDH1A3/RAD1/PADI2/NDUFS3/PLP1/HSPA5	11
BP	GO:1902686	mitochondrial outer membrane permeabilization involved in programmed cell death	11/2619	62/18670	0.2467	0.4504	0.3378	EYA2/BAD/GSK3B/GZMB/TMEM14A/PPP1R13B/YWHAH/TP53BP2/ACAA2/HIP1R/ATF2	11
BP	GO:0006767	water-soluble vitamin metabolic process	15/2619	88/18670	0.2471	0.4509	0.3382	THTPA/SLC2A3/FOLR1/CD320/MTHFD2/ENPP1/HAAO/PNPO/PCCB/PC/FOLR2/ABCC1/CYB5R3/LMBRD1/VNN1	15
BP	GO:0070125	mitochondrial translational elongation	15/2619	88/18670	0.2471	0.4509	0.3382	MRPL24/MRPL11/MRPL40/MRPL23/GFM1/MRPS33/MRPS28/MRPS17/MRPS22/MRPS11/MRPL17/MRPL20/MRPL18/MRPS14/MRPL4	15
BP	GO:0007281	germ cell development	41/2619	262/18670	0.2474	0.4514	0.3385	CDC25B/PTN/SRPK1/ERCC1/ASPM/ATM/NME5/UBE2J1/ANGPT2/KIT/ING2/BMP4/CELF1/KDM3A/BBS4/TTLL1/DPY19L2P2/DIAPH2/NPR2/DLD/IGF1/CCNB1/ANG/BRCA2/EREG/PRDM1/DEAF1/LGR5/YTHDC2/DND1/TMF1/CIB1/GDF9/DAZAP1/HSPA2/PIWIL2/INHBB/PTK2B/ABHD2/DAZL/FBXO5	41
BP	GO:0048675	axon extension	20/2619	121/18670	0.248	0.4523	0.3393	SEMA4D/MACF1/SEMA4A/SEMA3A/SPG11/NDN/APOE/GSK3B/SEMA4C/AUTS2/SEMA3F/VEGFA/SEMA3E/USP9X/CTTN/GOLGA4/TRPV2/CDKL5/CYFIP1/DSCAM	20
BP	GO:0001953	negative regulation of cell-matrix adhesion	8/2619	43/18670	0.2495	0.4541	0.3406	SERPINE1/POSTN/MAP4K4/MYOC/MMP12/SEMA3E/NF2/HOXA7	8
BP	GO:0031279	regulation of cyclase activity	8/2619	43/18670	0.2495	0.4541	0.3406	MAPK3/TIMP2/GUCA1A/NOS3/AKAP9/CACNA1D/GALR3/CCR2	8
BP	GO:0032459	regulation of protein oligomerization	8/2619	43/18670	0.2495	0.4541	0.3406	AIM2/CLU/APOE/IDE/CRYAB/PEX14/EP300/RIOK3	8
BP	GO:0043616	keratinocyte proliferation	8/2619	43/18670	0.2495	0.4541	0.3406	BCL11B/MED1/KLK8/EREG/FERMT1/PTPRK/HAS2/REG3A	8
BP	GO:0046473	phosphatidic acid metabolic process	8/2619	43/18670	0.2495	0.4541	0.3406	AGPAT1/PLA2G2D/AGPAT5/DGKA/PLD1/DGKZ/ACP6/LPCAT4	8
BP	GO:0051293	establishment of spindle localization	8/2619	43/18670	0.2495	0.4541	0.3406	NDE1/NUSAP1/ARHGEF2/NDC80/CLASP1/DYNC1H1/LLGL2/KPNB1	8
BP	GO:0086004	regulation of cardiac muscle cell contraction	8/2619	43/18670	0.2495	0.4541	0.3406	SRI/FGF13/STC1/BIN1/KCNJ2/AKAP9/RANGRF/FLNA	8
BP	GO:0007411	axon guidance	43/2619	276/18670	0.2508	0.4563	0.3423	SCN1B/SEMA4D/MAPK3/UNC5C/MYCBP2/SEMA4A/SOS1/SEMA3A/TUBB2B/NEO1/BSG/CHN1/GFRA1/BCL11B/MAPK7/SEMA4C/ERBB2/EFNA5/CYFIP2/FZD3/CXCR4/EPHB6/NTRK1/GRB10/KIF5C/SEMA3F/PIK3CB/EFNB1/RAC2/EPHA4/VEGFA/PLXND1/ARHGAP35/PRKCQ/SEMA3E/PIK3CD/PLXNA1/CYFIP1/DSCAM/SMO/MYH10/BDNF/PIK3CA	43
BP	GO:0015696	ammonium transport	18/2619	108/18670	0.2508	0.4563	0.3423	SLC18A2/TACR2/SNCA/SLC22A4/RHD/SYT11/SLC38A2/PINK1/ADA/FGF20/HRH3/SYT17/CHRNA3/VAMP7/TAF7/SEC14L1/SYT1/OAZ3	18
BP	GO:0003002	regionalization	54/2619	351/18670	0.251	0.4565	0.3424	SIX1/HOXA11/MTF2/SFRP1/NOTCH1/TCTN1/AR/HOXA10/HOXC10/SMAD3/FOXC1/MEOX1/SEMA3A/NLE1/ATM/SMARCD3/CTNNBIP1/IFT52/MDFI/BMP4/HOXB6/LEF1/MNS1/FKBP8/HOXA4/EVX1/FOXF1/POFUT1/WLS/SEMA3F/LRP5/SIX2/NBL1/RBPJ/EN1/EED/HOXB5/IFT140/CXXC4/TMED2/HOXD9/ABI1/HOXA5/BPTF/SIX3/HOXC11/RING1/EP300/ETS2/HOXA7/SMO/EMX2/PBX3/DDIT3	54
BP	GO:0051568	histone H3-K4 methylation	10/2619	56/18670	0.2542	0.4621	0.3466	WDR61/DNMT1/RLF/SETMAR/AUTS2/WDR5B/SETD1B/ARID4A/OGT/CXXC1	10
BP	GO:0086065	cell communication involved in cardiac conduction	10/2619	56/18670	0.2542	0.4621	0.3466	SCN1B/ATP1B1/SRI/KCNQ1/CACNB2/KCNN2/RANGRF/CACNA1D/CXADR/FLNA	10
BP	GO:0032642	regulation of chemokine production	14/2619	82/18670	0.255	0.463	0.3473	TREM2/RIPK2/IL4R/ADAM17/ELANE/POSTN/IFNG/IL6/EGR1/LPL/HIF1A/IL6R/TRIM32/TWIST1	14
BP	GO:0097581	lamellipodium organization	14/2619	82/18670	0.255	0.463	0.3473	PLEKHO1/NCK2/KIT/CD44/S1PR1/AUTS2/SNX2/ARHGEF7/RAC2/ABI1/PARVB/CTTN/GOLPH3/CYFIP1	14
BP	GO:1905954	positive regulation of lipid localization	14/2619	82/18670	0.255	0.463	0.3473	NFKBIA/TNFRSF11A/APOE/NFKB1/NR1H2/SCP2/ATP8A1/P2RX4/PLA2R1/LPL/TMF1/TAC1/GAL/FABP3	14
BP	GO:0008088	axo-dendritic transport	12/2619	69/18670	0.2555	0.4631	0.3473	UCHL1/SPG11/BLOC1S1/TRAK1/HSPB1/KIF5C/KIF4A/DYNC1H1/SFPQ/SOD1/SPAST/HIF1A	12
BP	GO:0034381	plasma lipoprotein particle clearance	12/2619	69/18670	0.2555	0.4631	0.3473	LIPC/APOM/LRPAP1/APOE/AP2M1/CNPY2/HNRNPK/CES3/APOC1/LIPA/NPC1/LMF1	12
BP	GO:0006023	aminoglycan biosynthetic process	19/2619	115/18670	0.2557	0.4631	0.3473	GPC5/UST/ANGPT1/SDC1/B4GALT2/EGF/EXT2/NFKB1/HEXA/ST3GAL2/CHST15/EXTL2/B4GALT7/PDGFB/HAS2/VCAN/CHST12/KERA/B4GALT3	19
BP	GO:0002714	positive regulation of B cell mediated immunity	7/2619	37/18670	0.2561	0.4631	0.3473	TFRC/PTPRC/HLA-E/CD28/CD40/XCL1/TNFSF4	7
BP	GO:0002891	positive regulation of immunoglobulin mediated immune response	7/2619	37/18670	0.2561	0.4631	0.3473	TFRC/PTPRC/HLA-E/CD28/CD40/XCL1/TNFSF4	7
BP	GO:0007431	salivary gland development	7/2619	37/18670	0.2561	0.4631	0.3473	HGF/SEMA3A/EGFR/LAMA5/PLXND1/PLXNA1/XBP1	7
BP	GO:0014037	Schwann cell differentiation	7/2619	37/18670	0.2561	0.4631	0.3473	NTRK2/NAB1/ADAM22/MYOC/SOD1/FA2H/CDK1	7
BP	GO:0031076	embryonic camera-type eye development	7/2619	37/18670	0.2561	0.4631	0.3473	ARID1A/IFT140/ALDH1A3/PHACTR4/SIX3/TH/TWIST1	7
BP	GO:0034405	response to fluid shear stress	7/2619	37/18670	0.2561	0.4631	0.3473	MAPK7/ASS1/NOS3/CA2/P2RX4/HAS2/PTK2B	7
BP	GO:0045730	respiratory burst	7/2619	37/18670	0.2561	0.4631	0.3473	SLAMF8/INSR/RAC2/SLC11A1/PRDX2/PIK3CD/NCF1	7
BP	GO:0046839	phospholipid dephosphorylation	7/2619	37/18670	0.2561	0.4631	0.3473	EPHX2/MTMR4/MTMR9/SYNJ1/MTMR6/MTMR1/INPP5E	7
BP	GO:0051084	'de novo' posttranslational protein folding	7/2619	37/18670	0.2561	0.4631	0.3473	GAK/HSPH1/DNAJB14/HSPA6/BAG1/HSPA2/HSPA5	7
BP	GO:0060323	head morphogenesis	7/2619	37/18670	0.2561	0.4631	0.3473	CRISPLD2/NIPBL/LEF1/ASPH/PLEKHA1/EP300/SGPL1	7
BP	GO:0071276	cellular response to cadmium ion	7/2619	37/18670	0.2561	0.4631	0.3473	MAPK3/EGFR/DAXX/CHUK/AKR1C3/SOD1/NCF1	7
BP	GO:0071542	dopaminergic neuron differentiation	7/2619	37/18670	0.2561	0.4631	0.3473	SFRP1/GSK3B/FGF20/EN1/VEGFA/CSNK1E/HIF1A	7
BP	GO:0051216	cartilage development	33/2619	209/18670	0.2575	0.4654	0.3491	PITX1/HOXA11/EFEMP1/SCARA3/WNT5B/SOX9/MAPK3/MGP/SMAD3/PTH1R/LTBP3/STC1/RUNX3/BMP4/GDF5/WNT11/CD44/OSR2/COMP/FGF18/SIX2/MMP13/ZNF219/SCIN/COL6A3/HIF1A/MBL2/HOXA5/MAF/TYMS/TIMP1/HMGA2/SATB2	33
BP	GO:0097485	neuron projection guidance	43/2619	277/18670	0.2588	0.4677	0.3508	SCN1B/SEMA4D/MAPK3/UNC5C/MYCBP2/SEMA4A/SOS1/SEMA3A/TUBB2B/NEO1/BSG/CHN1/GFRA1/BCL11B/MAPK7/SEMA4C/ERBB2/EFNA5/CYFIP2/FZD3/CXCR4/EPHB6/NTRK1/GRB10/KIF5C/SEMA3F/PIK3CB/EFNB1/RAC2/EPHA4/VEGFA/PLXND1/ARHGAP35/PRKCQ/SEMA3E/PIK3CD/PLXNA1/CYFIP1/DSCAM/SMO/MYH10/BDNF/PIK3CA	43
BP	GO:0070126	mitochondrial translational termination	15/2619	89/18670	0.2614	0.4712	0.3534	MTRF1/MRPL24/MRPL11/MRPL40/MRPL23/MRPS33/MRPS28/MRPS17/MRPS22/MRPS11/MRPL17/MRPL20/MRPL18/MRPS14/MRPL4	15
BP	GO:0071826	ribonucleoprotein complex subunit organization	45/2619	291/18670	0.2618	0.4712	0.3534	SRPK1/SETX/ADAR/CIRBP/CELF2/ATR/LSM4/NLE1/ATM/SF3B1/PUM2/PRMT5/SART3/LSM3/NOL3/CELF1/RPL12/CPSF7/MRPL11/DDX23/MDN1/SNUPN/SFSWAP/PTBP2/EIF2S3/EIF3A/DYNC1H1/RPS5/RUVBL2/SCAF11/EIF3I/DDX1/EIF2D/SNRPD2/AGO3/PRKAA1/TXNL4A/YTHDC1/MRPS11/LUC7L/MRPL20/EIF6/STYXL1/GEMIN2/RPLP0	45
BP	GO:0007269	neurotransmitter secretion	27/2619	169/18670	0.2619	0.4712	0.3534	SLC18A2/TACR2/SNCA/RIMS3/PREPL/PRKCB/SYT11/SYNJ1/PFN2/MCTP1/GSK3B/HRH3/GPER1/SYT17/LIN7B/CHRNA3/PTPRN2/SNCAIP/HCRT/ADCY1/VAMP2/CACNB2/CACNA1D/SYT1/SYN1/RAP1B/NAPA	27
BP	GO:0015698	inorganic anion transport	27/2619	169/18670	0.2619	0.4712	0.3534	FXYD1/ENPP1/SLC12A8/ANKH/LRRC8B/APOL1/GABRB1/PRNP/RACGAP1/SLC12A7/GABRA4/CLCA2/CLIC5/TSPO/SLC11A1/CA2/ANO1/ABCB1/ANO10/VDAC3/CCT8L2/SLC20A2/ADAMTS8/SLC4A7/CEBPB/ATF4/SLC1A1	27
BP	GO:0090150	establishment of protein localization to membrane	51/2619	332/18670	0.2619	0.4712	0.3534	MICALL1/ATP1B1/ZDHHC18/FIS1/MACF1/PREPL/VPS37C/NDUFA13/PEX19/RFTN1/TIMM10/BAD/ZDHHC4/EGFR/PRNP/ERBB2/GZMB/RPS8/PPP1R13B/RPL12/ANK3/BBS1/YWHAH/VAMP3/RPS11/PRKCI/TP53BP2/SEC16A/VAMP7/RPL10A/ZDHHC3/UBL4A/RPS5/SEC61A2/OPTN/VAMP2/SRP54/RPL27A/SSR2/CIB1/GOLGA4/RPL8/RAB11B/RPL19/GOLPH3/SAMM50/NPC1/HSPA5/RPL35A/RPLP0/NCF1	51
BP	GO:0010718	positive regulation of epithelial to mesenchymal transition	9/2619	50/18670	0.2622	0.4712	0.3534	NOTCH1/SMAD3/FOXC1/EZH2/BMP4/LEF1/IL6/TCF7L2/TWIST1	9
BP	GO:0031113	regulation of microtubule polymerization	9/2619	50/18670	0.2622	0.4712	0.3534	STMN2/SNCA/ARL2/MAPRE3/DRG1/CDH5/CLASP1/AKAP9/RANGRF	9
BP	GO:0032873	negative regulation of stress-activated MAPK cascade	9/2619	50/18670	0.2622	0.4712	0.3534	SFRP1/PINK1/DNAJA1/PTPN22/FOXM1/MYC/NCOR1/CYLD/TAOK3	9
BP	GO:0070303	negative regulation of stress-activated protein kinase signaling cascade	9/2619	50/18670	0.2622	0.4712	0.3534	SFRP1/PINK1/DNAJA1/PTPN22/FOXM1/MYC/NCOR1/CYLD/TAOK3	9
BP	GO:0070534	protein K63-linked ubiquitination	9/2619	50/18670	0.2622	0.4712	0.3534	UBE2D4/TRIP12/BIRC2/PTPN22/PELI1/UBE2E3/MAGEL2/NOD2/UBR5	9
BP	GO:0002082	regulation of oxidative phosphorylation	6/2619	31/18670	0.2624	0.4712	0.3534	NUPR1/COX7A1/SNCA/PINK1/CCNB1/CDK1	6
BP	GO:0002888	positive regulation of myeloid leukocyte mediated immunity	6/2619	31/18670	0.2624	0.4712	0.3534	IL4R/HLA-E/FGR/VAMP7/DDX1/DDX21	6
BP	GO:0006482	protein demethylation	6/2619	31/18670	0.2624	0.4712	0.3534	JARID2/KDM5A/KDM2A/KDM3A/KDM7A/JMJD6	6
BP	GO:0008214	protein dealkylation	6/2619	31/18670	0.2624	0.4712	0.3534	JARID2/KDM5A/KDM2A/KDM3A/KDM7A/JMJD6	6
BP	GO:0009154	purine ribonucleotide catabolic process	6/2619	31/18670	0.2624	0.4712	0.3534	PDE1A/NUDT9/NUDT11/ACAT1/NT5E/AMPD3	6
BP	GO:0030149	sphingolipid catabolic process	6/2619	31/18670	0.2624	0.4712	0.3534	SPHK1/ASAH1/GM2A/NEU1/SGPL1/PSAP	6
BP	GO:0043304	regulation of mast cell degranulation	6/2619	31/18670	0.2624	0.4712	0.3534	IL4R/FGR/FOXF1/RAC2/VAMP7/IL13RA2	6
BP	GO:0045648	positive regulation of erythrocyte differentiation	6/2619	31/18670	0.2624	0.4712	0.3534	STAT1/MED1/ZNF16/HIF1A/ID2/TRIM58	6
BP	GO:0048710	regulation of astrocyte differentiation	6/2619	31/18670	0.2624	0.4712	0.3534	NOTCH1/BIN1/ID4/IL6/EPHA4/ID2	6
BP	GO:0050685	positive regulation of mRNA processing	6/2619	31/18670	0.2624	0.4712	0.3534	CIRBP/PRDX6/CCNB1/NCBP2/DAZAP1/NUP98	6
BP	GO:0086011	membrane repolarization during action potential	6/2619	31/18670	0.2624	0.4712	0.3534	ATP1B1/KCNQ1/KCNJ2/KCNJ8/KCNN2/FLNA	6
BP	GO:0090659	walking behavior	6/2619	31/18670	0.2624	0.4712	0.3534	ZIC1/UCHL1/SPG11/EPHA4/NPC1/PSAP	6
BP	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	6/2619	31/18670	0.2624	0.4712	0.3534	CLU/ING2/USP47/CD44/TAF9B/TRIM32	6
BP	GO:0000380	alternative mRNA splicing, via spliceosome	13/2619	76/18670	0.2633	0.4719	0.354	CELF2/MBNL3/SART3/FAM172A/CELF1/RBM15/SFSWAP/SRSF4/HNRNPA1/SRSF8/SFPQ/RBM19/SREK1	13
BP	GO:0007588	excretion	11/2619	63/18670	0.2638	0.4719	0.354	TACR2/COMT/STC1/SLC22A18/CHRNA3/AGT/GRHPR/TAC1/PSAP/CORIN/NEDD4L	11
BP	GO:0046622	positive regulation of organ growth	11/2619	63/18670	0.2638	0.4719	0.354	NOTCH1/PIM1/ZFPM2/IGF1/TBX5/CCNB1/RBPJ/PIN1/CDK1/ERBB4/SMO	11
BP	GO:1904377	positive regulation of protein localization to cell periphery	11/2619	63/18670	0.2638	0.4719	0.354	TREM2/EGFR/PRNP/PRKCH/GPER1/IFNG/PRKCI/RANGRF/CIB1/LGALS3/SORBS1	11
BP	GO:0050853	B cell receptor signaling pathway	21/2619	129/18670	0.2642	0.4719	0.354	PLCG2/PRKCB/PTPRC/CD38/RFTN1/ITK/CTLA4/PRKCH/IGHM/PTPN22/PLEKHA1/CD81/TRBC1/LCK/CD19/IGLL5/IGLC1/LIME1/PIK3CD/MS4A1/LPXN	21
BP	GO:0050808	synapse organization	62/2619	408/18670	0.2659	0.4719	0.354	SIX1/PCDHB13/PTN/TREM2/LGMN/CDH2/PCDHB6/SEMA4D/SNCA/SEMA4A/LILRB2/SLC7A11/PTPRF/PCDHB3/DOCK10/PRNP/PFN2/BAIAP2/CX3CR1/ZNF365/NTRK2/APOE/INSR/PCDH17/PCDHB11/ERBB2/EFNA5/MAGI2/ANK3/SIPA1L1/GPM6A/F2R/NTRK1/KLK8/SEMA3F/GHSR/CDC20/EPHA4/PLXND1/PIN1/SEMA3E/CHRNB1/CACNB2/CAMK1/SPOCK2/CTTN/ZC4H2/THBS2/CDKL5/COL4A1/ERBB4/CYFIP1/CAPRIN2/ACTN1/SYN1/DSCAM/SEZ6L/CAMK2B/ACTR2/MYH10/BDNF/STAU1	62
BP	GO:0006323	DNA packaging	33/2619	210/18670	0.2668	0.4719	0.354	SRPK1/NAP1L3/SMCHD1/SOX9/NIPBL/NAP1L2/SART3/SET/TPR/NUSAP1/GPER1/NCAPH/BANF1/DAXX/CCNB1/NCAPG/NASP/ATRX/HJURP/TOP2A/CENPT/KAT6A/SMC4/SMARCA5/AKAP8/TSPYL1/DFFB/CDK1/CENPC/TSPYL5/UBN1/HMGA1/HMGA2	33
BP	GO:0010660	regulation of muscle cell apoptotic process	16/2619	96/18670	0.2672	0.4719	0.354	NUPR1/MAP3K5/JAK2/CFLAR/DNMT1/PDE1A/HSPB6/NOL3/PPARG/ARRB1/IFNG/AGT/IGF1/CXCR2/PTK2B/ATF4	16
BP	GO:0030516	regulation of axon extension	16/2619	96/18670	0.2672	0.4719	0.354	SEMA4D/MACF1/SEMA4A/SEMA3A/APOE/GSK3B/SEMA4C/SEMA3F/VEGFA/SEMA3E/CTTN/GOLGA4/TRPV2/CDKL5/CYFIP1/DSCAM	16
BP	GO:0021953	central nervous system neuron differentiation	29/2619	183/18670	0.2673	0.4719	0.354	SFRP1/SCN1B/TCTN1/HOXC10/MYCBP2/RORA/SPOCK1/SEMA3A/GABRB1/AGTPBP1/NTRK2/BCL11B/HERC1/GDPD5/EVX1/ID4/EPHA4/UBB/ARHGAP35/TSKU/CSNK1E/NFE2L1/UQCRQ/ZC4H2/OLIG2/ERBB4/C21orf91/SMO/SATB2	29
BP	GO:0002068	glandular epithelial cell development	5/2619	25/18670	0.2681	0.4719	0.354	BAD/GSK3B/BMP4/INSM1/SMO	5
BP	GO:0003309	type B pancreatic cell differentiation	5/2619	25/18670	0.2681	0.4719	0.354	BAD/GSK3B/BMP4/INSM1/SMO	5
BP	GO:0006688	glycosphingolipid biosynthetic process	5/2619	25/18670	0.2681	0.4719	0.354	UGCG/PRKAA1/FA2H/ST8SIA2/B4GALT3	5
BP	GO:0006851	mitochondrial calcium ion transmembrane transport	5/2619	25/18670	0.2681	0.4719	0.354	PHB/MICU1/YME1L1/STOML2/LETM1	5
BP	GO:0009404	toxin metabolic process	5/2619	25/18670	0.2681	0.4719	0.354	CBS/AKR7A3/ARL1/MPST/TH	5
BP	GO:0009648	photoperiodism	5/2619	25/18670	0.2681	0.4719	0.354	SIK1/PML/AGRP/ID2/CRY1	5
BP	GO:0032104	regulation of response to extracellular stimulus	5/2619	25/18670	0.2681	0.4719	0.354	MED1/BBS4/GHSR/TRIM24/KANK2	5
BP	GO:0032107	regulation of response to nutrient levels	5/2619	25/18670	0.2681	0.4719	0.354	MED1/BBS4/GHSR/TRIM24/KANK2	5
BP	GO:0032400	melanosome localization	5/2619	25/18670	0.2681	0.4719	0.354	MREG/RAB27A/BBS4/DCTN2/RAB11B	5
BP	GO:0032509	endosome transport via multivesicular body sorting pathway	5/2619	25/18670	0.2681	0.4719	0.354	VPS37C/CHMP2A/TMEM50B/SORT1/CHMP1B	5
BP	GO:0045672	positive regulation of osteoclast differentiation	5/2619	25/18670	0.2681	0.4719	0.354	TREM2/IFNG/TYROBP/CA2/CREB1	5
BP	GO:0045830	positive regulation of isotype switching	5/2619	25/18670	0.2681	0.4719	0.354	TFRC/PTPRC/CD28/CD40/TNFSF4	5
BP	GO:0051654	establishment of mitochondrion localization	5/2619	25/18670	0.2681	0.4719	0.354	UCHL1/TRAK1/UBB/SPAST/HIF1A	5
BP	GO:0072202	cell differentiation involved in metanephros development	5/2619	25/18670	0.2681	0.4719	0.354	STAT1/BMP4/SIX2/PDGFB/SMO	5
BP	GO:0072273	metanephric nephron morphogenesis	5/2619	25/18670	0.2681	0.4719	0.354	STAT1/SOX9/BMP4/SIX2/SMO	5
BP	GO:1900101	regulation of endoplasmic reticulum unfolded protein response	5/2619	25/18670	0.2681	0.4719	0.354	NCK2/PTPN2/ATF6/XBP1/HSPA5	5
BP	GO:2000482	regulation of interleukin-8 secretion	5/2619	25/18670	0.2681	0.4719	0.354	PTPN22/F2R/CD58/CD2/FCN1	5
BP	GO:0021782	glial cell development	19/2619	116/18670	0.2684	0.4719	0.354	TREM2/LAMC3/CLU/EGFR/NTRK2/ADAM22/ID4/IFNG/MXRA8/IL6/MYOC/SOD1/ERCC2/FA2H/ID2/KRAS/PLP1/SMO/TENM4	19
BP	GO:0034219	carbohydrate transmembrane transport	19/2619	116/18670	0.2684	0.4719	0.354	SLC2A3/ENPP1/PRKCB/PID1/RTN2/INSR/OSBPL8/PEA15/SLC2A6/SLC5A3/SLC2A11/SLC2A9/GRB10/PRKCI/IGF1/SORT1/SLC2A5/SLC2A10/SORBS1	19
BP	GO:2000736	regulation of stem cell differentiation	19/2619	116/18670	0.2684	0.4719	0.354	PTN/NOTCH1/SOX9/FOXC1/PSMB9/LTBP3/N4BP2L2/BMP4/PUS7/PSMC2/KDM3A/PSMB6/TBX5/PSMC3/PSMD8/PSMB5/ZFP36L2/PSMD10/TCF3	19
BP	GO:0017157	regulation of exocytosis	34/2619	217/18670	0.2689	0.4719	0.354	NOTCH1/MICAL1/RPH3AL/SNCA/RIMS3/HLA-F/PREPL/PRKCB/SYT11/RAB27A/IL4R/SDC1/PFN2/GSK3B/RALA/FGR/SYT17/FOXF1/IFNG/CHMP2A/RAC2/VAMP7/CLASP1/ADCY1/VAMP2/CACNB2/CACNA1D/SYT1/RAB15/SYN1/RAP1B/IL13RA2/CCR2/NAPA	34
BP	GO:0045637	regulation of myeloid cell differentiation	39/2619	251/18670	0.2691	0.4719	0.354	NFKBIA/SFRP1/P4HTM/TREM2/STAT1/FBXW7/TCTA/PRKCB/WDR61/CTNNBIP1/GPR171/LEF1/MED1/PTPN2/IFNG/TRIB1/RBM15/HMGB3/MYC/TYROBP/ZNF16/CA2/SCIN/PRKCQ/HIF1A/AGO3/HOXA5/HDAC1/CIB1/CREB1/ID2/LGALS3/KAT2B/EIF6/EP300/PTK2B/HOXA7/CEBPB/TRIM58	39
BP	GO:0097479	synaptic vesicle localization	26/2619	163/18670	0.2696	0.4719	0.354	CDH2/SNCA/RIMS3/PREPL/PRKCB/SYT11/RAB27A/SPG11/SYNJ1/PFN2/PINK1/GSK3B/PCDH17/BLOC1S1/TMEM230/MAGI2/SYT17/KIF5C/ADCY1/VAMP2/CACNB2/CACNA1D/SYT1/SYN1/RAP1B/NAPA	26
BP	GO:0090287	regulation of cellular response to growth factor stimulus	45/2619	292/18670	0.2698	0.4719	0.354	SFRP1/NOTCH1/FOLR1/PRKD2/CXCL13/SMAD3/GOT1/PRKCB/CFLAR/MTMR4/ADAM17/NEO1/ITGA5/TRIM33/NTF3/HTRA1/ING2/BMP4/GDF5/ADAMTSL2/RNF111/TNMD/ZNF451/CYFIP2/FKBP8/GRB10/CDH5/CD63/AGT/FGF18/NBL1/CDKN1C/RBPJ/CHRDL1/VEGFA/PIN1/UBB/ADAMTS3/FERMT1/LTBP4/HIF1A/CYFIP1/EP300/HSPA5/ZNF423	45
BP	GO:1901879	regulation of protein depolymerization	14/2619	83/18670	0.27	0.4719	0.354	STMN2/TMOD1/FGF13/CAPZA1/ARHGEF2/ASPH/TAOK1/TMOD2/CLASP1/SCIN/SPAST/KATNB1/CIB1/LIMA1	14
BP	GO:0007007	inner mitochondrial membrane organization	8/2619	44/18670	0.2704	0.4719	0.354	NDUFA13/TIMM10/PINK1/TMEM11/APOO/TAZ/SAMM50/LETM1	8
BP	GO:0014002	astrocyte development	8/2619	44/18670	0.2704	0.4719	0.354	TREM2/LAMC3/EGFR/IFNG/IL6/KRAS/PLP1/SMO	8
BP	GO:0018023	peptidyl-lysine trimethylation	8/2619	44/18670	0.2704	0.4719	0.354	WDR61/ARID4B/ATRX/VCPKMT/ARID4A/OGT/SETD2/SUV39H2	8
BP	GO:0034105	positive regulation of tissue remodeling	8/2619	44/18670	0.2704	0.4719	0.354	TFRC/IL15/EGFR/LTBP3/TNFRSF11A/ROCK1/CA2/PPP3CA	8
BP	GO:0046189	phenol-containing compound biosynthetic process	8/2619	44/18670	0.2704	0.4719	0.354	GCH1/SNCA/SLC7A11/MOXD1/HDC/INSM1/DCT/TH	8
BP	GO:0060999	positive regulation of dendritic spine development	8/2619	44/18670	0.2704	0.4719	0.354	BAIAP2/APOE/CAMK1/CDKL5/CAPRIN2/C21orf91/CAMK2B/ACTR2	8
BP	GO:0070266	necroptotic process	8/2619	44/18670	0.2704	0.4719	0.354	BIRC3/SLC25A4/FAS/CFLAR/BIRC2/ARHGEF2/PELI1/CYLD	8
BP	GO:0090382	phagosome maturation	8/2619	44/18670	0.2704	0.4719	0.354	SLAMF8/MREG/ATP6V0D1/SYT11/SPG11/TCIRG1/ATP6V0E2/RAB20	8
BP	GO:0002679	respiratory burst involved in defense response	3/2619	13/18670	0.2714	0.4719	0.354	SLAMF8/PRDX2/PIK3CD	3
BP	GO:0006995	cellular response to nitrogen starvation	3/2619	13/18670	0.2714	0.4719	0.354	GABARAPL1/GABARAPL2/GABARAP	3
BP	GO:0009143	nucleoside triphosphate catabolic process	3/2619	13/18670	0.2714	0.4719	0.354	ENPP1/ADA/SAMHD1	3
BP	GO:0009313	oligosaccharide catabolic process	3/2619	13/18670	0.2714	0.4719	0.354	MAN2B2/GM2A/NEU1	3
BP	GO:0009635	response to herbicide	3/2619	13/18670	0.2714	0.4719	0.354	DAXX/HNRNPA1/TH	3
BP	GO:0010745	negative regulation of macrophage derived foam cell differentiation	3/2619	13/18670	0.2714	0.4719	0.354	NFKBIA/PPARG/NR1H2	3
BP	GO:0010872	regulation of cholesterol esterification	3/2619	13/18670	0.2714	0.4719	0.354	APOE/APOC1/AGT	3
BP	GO:0018206	peptidyl-methionine modification	3/2619	13/18670	0.2714	0.4719	0.354	METAP1/NAA16/METAP2	3
BP	GO:0019511	peptidyl-proline hydroxylation	3/2619	13/18670	0.2714	0.4719	0.354	P4HTM/CRTAP/EGLN3	3
BP	GO:0019627	urea metabolic process	3/2619	13/18670	0.2714	0.4719	0.354	CEBPA/ASS1/CPS1	3
BP	GO:0021978	telencephalon regionalization	3/2619	13/18670	0.2714	0.4719	0.354	BMP4/SIX3/EMX2	3
BP	GO:0030205	dermatan sulfate metabolic process	3/2619	13/18670	0.2714	0.4719	0.354	UST/VCAN/CHST12	3
BP	GO:0031115	negative regulation of microtubule polymerization	3/2619	13/18670	0.2714	0.4719	0.354	STMN2/SNCA/CDH5	3
BP	GO:0031274	positive regulation of pseudopodium assembly	3/2619	13/18670	0.2714	0.4719	0.354	CDC42EP3/KIT/CCR7	3
BP	GO:0031953	negative regulation of protein autophosphorylation	3/2619	13/18670	0.2714	0.4719	0.354	ENPP1/PTPRC/MVP	3
BP	GO:0032530	regulation of microvillus organization	3/2619	13/18670	0.2714	0.4719	0.354	ATP8B1/PLD1/PODXL	3
BP	GO:0033623	regulation of integrin activation	3/2619	13/18670	0.2714	0.4719	0.354	CXCL13/PTGER4/RASIP1	3
BP	GO:0034982	mitochondrial protein processing	3/2619	13/18670	0.2714	0.4719	0.354	MIPEP/YME1L1/STOML2	3
BP	GO:0035641	locomotory exploration behavior	3/2619	13/18670	0.2714	0.4719	0.354	APOE/PENK/C12orf10	3
BP	GO:0036109	alpha-linolenic acid metabolic process	3/2619	13/18670	0.2714	0.4719	0.354	SCP2/ACOX1/ACOT8	3
BP	GO:0042538	hyperosmotic salinity response	3/2619	13/18670	0.2714	0.4719	0.354	AKR1B1/MICU1/LETM1	3
BP	GO:0043116	negative regulation of vascular permeability	3/2619	13/18670	0.2714	0.4719	0.354	ANGPT1/DDAH1/ARHGAP35	3
BP	GO:0043201	response to leucine	3/2619	13/18670	0.2714	0.4719	0.354	UBR2/RRAGD/SESN1	3
BP	GO:0043562	cellular response to nitrogen levels	3/2619	13/18670	0.2714	0.4719	0.354	GABARAPL1/GABARAPL2/GABARAP	3
BP	GO:0045602	negative regulation of endothelial cell differentiation	3/2619	13/18670	0.2714	0.4719	0.354	NOTCH4/VEGFA/FOXJ2	3
BP	GO:0045820	negative regulation of glycolytic process	3/2619	13/18670	0.2714	0.4719	0.354	NUPR1/CBFA2T3/DDIT4	3
BP	GO:0046415	urate metabolic process	3/2619	13/18670	0.2714	0.4719	0.354	SLC2A9/PNP/PRPS1	3
BP	GO:0048505	regulation of timing of cell differentiation	3/2619	13/18670	0.2714	0.4719	0.354	NOTCH1/GDPD5/RBPJ	3
BP	GO:0048711	positive regulation of astrocyte differentiation	3/2619	13/18670	0.2714	0.4719	0.354	NOTCH1/BIN1/ID2	3
BP	GO:0048715	negative regulation of oligodendrocyte differentiation	3/2619	13/18670	0.2714	0.4719	0.354	NOTCH1/ID4/ID2	3
BP	GO:0050713	negative regulation of interleukin-1 beta secretion	3/2619	13/18670	0.2714	0.4719	0.354	TNFAIP3/CARD8/PML	3
BP	GO:0060340	positive regulation of type I interferon-mediated signaling pathway	3/2619	13/18670	0.2714	0.4719	0.354	TBK1/IRF3/MMP12	3
BP	GO:0061469	regulation of type B pancreatic cell proliferation	3/2619	13/18670	0.2714	0.4719	0.354	SFRP1/NUPR1/WDR13	3
BP	GO:0070986	left/right axis specification	3/2619	13/18670	0.2714	0.4719	0.354	NOTCH1/MNS1/SMO	3
BP	GO:0071287	cellular response to manganese ion	3/2619	13/18670	0.2714	0.4719	0.354	ATF4/HSPA5/TH	3
BP	GO:0071696	ectodermal placode development	3/2619	13/18670	0.2714	0.4719	0.354	SIX1/DKK4/HDAC1	3
BP	GO:0071872	cellular response to epinephrine stimulus	3/2619	13/18670	0.2714	0.4719	0.354	SNCA/KCNQ1/ATP2B4	3
BP	GO:0090646	mitochondrial tRNA processing	3/2619	13/18670	0.2714	0.4719	0.354	HSD17B10/PUS1/TRMT5	3
BP	GO:0090713	immunological memory process	3/2619	13/18670	0.2714	0.4719	0.354	TNFRSF14/CD81/TNFSF4	3
BP	GO:0098712	L-glutamate import across plasma membrane	3/2619	13/18670	0.2714	0.4719	0.354	SLC7A11/ARL6IP5/SLC1A1	3
BP	GO:0098787	mRNA cleavage involved in mRNA processing	3/2619	13/18670	0.2714	0.4719	0.354	CPSF7/NCBP2/CSTF2	3
BP	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response	3/2619	13/18670	0.2714	0.4719	0.354	PTPN2/ATF6/XBP1	3
BP	GO:1901550	regulation of endothelial cell development	3/2619	13/18670	0.2714	0.4719	0.354	ROCK1/CDH5/VEGFA	3
BP	GO:1902713	regulation of interferon-gamma secretion	3/2619	13/18670	0.2714	0.4719	0.354	RASGRP1/PTPN22/CD2	3
BP	GO:1902894	negative regulation of pri-miRNA transcription by RNA polymerase II	3/2619	13/18670	0.2714	0.4719	0.354	SOX9/BMP4/PDGFB	3
BP	GO:1902902	negative regulation of autophagosome assembly	3/2619	13/18670	0.2714	0.4719	0.354	NUPR1/PINK1/SEC22B	3
BP	GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding	3/2619	13/18670	0.2714	0.4719	0.354	FBXW7/EP300/DDIT3	3
BP	GO:1903140	regulation of establishment of endothelial barrier	3/2619	13/18670	0.2714	0.4719	0.354	ROCK1/CDH5/VEGFA	3
BP	GO:1904925	positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization	3/2619	13/18670	0.2714	0.4719	0.354	VPS13C/PINK1/OPTN	3
BP	GO:1990403	embryonic brain development	3/2619	13/18670	0.2714	0.4719	0.354	TUBB2B/EN1/IFT140	3
BP	GO:2000052	positive regulation of non-canonical Wnt signaling pathway	3/2619	13/18670	0.2714	0.4719	0.354	SFRP1/PLEKHA4/CSNK1E	3
BP	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining	3/2619	13/18670	0.2714	0.4719	0.354	PARP3/SMCHD1/SETMAR	3
BP	GO:0001573	ganglioside metabolic process	4/2619	19/18670	0.272	0.4719	0.354	CLN6/GM2A/NEU1/ST8SIA2	4
BP	GO:0001710	mesodermal cell fate commitment	4/2619	19/18670	0.272	0.4719	0.354	HOXA11/EYA2/BMP4/SIX2	4
BP	GO:0001832	blastocyst growth	4/2619	19/18670	0.272	0.4719	0.354	NBN/GINS1/IGF1/BRCA2	4
BP	GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin	4/2619	19/18670	0.272	0.4719	0.354	CPA3/CMA1/F2R/CTSG	4
BP	GO:0002076	osteoblast development	4/2619	19/18670	0.272	0.4719	0.354	SMAD3/PTH1R/LRP5/SATB2	4
BP	GO:0003422	growth plate cartilage morphogenesis	4/2619	19/18670	0.272	0.4719	0.354	SCARA3/STC1/COL6A3/MBL2	4
BP	GO:0006534	cysteine metabolic process	4/2619	19/18670	0.272	0.4719	0.354	CBS/SLC7A11/MPST/AHCY	4
BP	GO:0006555	methionine metabolic process	4/2619	19/18670	0.272	0.4719	0.354	BHMT2/SMS/MSRA/AHCY	4
BP	GO:0010544	negative regulation of platelet activation	4/2619	19/18670	0.272	0.4719	0.354	APOE/NOS3/PDGFB/SH2B3	4
BP	GO:0015669	gas transport	4/2619	19/18670	0.272	0.4719	0.354	MYC/IPCEF1/CA2/HBB	4
BP	GO:0032288	myelin assembly	4/2619	19/18670	0.272	0.4719	0.354	PIKFYVE/PMP22/ERCC2/TENM4	4
BP	GO:0032930	positive regulation of superoxide anion generation	4/2619	19/18670	0.272	0.4719	0.354	EGFR/AGT/TYROBP/SOD1	4
BP	GO:0034471	ncRNA 5'-end processing	4/2619	19/18670	0.272	0.4719	0.354	HSD17B10/POP7/RPP14/USP14	4
BP	GO:0035728	response to hepatocyte growth factor	4/2619	19/18670	0.272	0.4719	0.354	LGMN/HGF/MED1/CREB1	4
BP	GO:0046112	nucleobase biosynthetic process	4/2619	19/18670	0.272	0.4719	0.354	ADA/CPS1/CTPS1/PRPS1	4
BP	GO:0048025	negative regulation of mRNA splicing, via spliceosome	4/2619	19/18670	0.272	0.4719	0.354	HNRNPA2B1/HNRNPK/SFSWAP/SRSF4	4
BP	GO:0060252	positive regulation of glial cell proliferation	4/2619	19/18670	0.272	0.4719	0.354	PRKCH/PRKCI/TSPO/IL6	4
BP	GO:0060716	labyrinthine layer blood vessel development	4/2619	19/18670	0.272	0.4719	0.354	RBPJ/TMED2/PLCD1/GGNBP2	4
BP	GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response	4/2619	19/18670	0.272	0.4719	0.354	HLA-G/DDX1/DDX21/BCL10	4
BP	GO:0071731	response to nitric oxide	4/2619	19/18670	0.272	0.4719	0.354	CCNA2/CFLAR/CCR7/HNRNPD	4
BP	GO:1900409	positive regulation of cellular response to oxidative stress	4/2619	19/18670	0.272	0.4719	0.354	FBXW7/SFPQ/MCL1/SOD1	4
BP	GO:1902170	cellular response to reactive nitrogen species	4/2619	19/18670	0.272	0.4719	0.354	MAP3K5/CCNA2/CFLAR/HNRNPD	4
BP	GO:1903798	regulation of production of miRNAs involved in gene silencing by miRNA	4/2619	19/18670	0.272	0.4719	0.354	EGFR/BMP4/PPP3CA/NCOR1	4
BP	GO:1905288	vascular associated smooth muscle cell apoptotic process	4/2619	19/18670	0.272	0.4719	0.354	DNMT1/PPARG/IGF1/ATF4	4
BP	GO:1905459	regulation of vascular associated smooth muscle cell apoptotic process	4/2619	19/18670	0.272	0.4719	0.354	DNMT1/PPARG/IGF1/ATF4	4
BP	GO:1990182	exosomal secretion	4/2619	19/18670	0.272	0.4719	0.354	RAB27A/SDC1/IFNG/CHMP2A	4
BP	GO:0007004	telomere maintenance via telomerase	12/2619	70/18670	0.2721	0.4719	0.354	MAPK3/ATR/TNKS2/ATM/NHP2/RPA1/DCP2/HMBOX1/AURKB/HNRNPA1/PRKCQ/RAD50	12
BP	GO:2001259	positive regulation of cation channel activity	12/2619	70/18670	0.2721	0.4719	0.354	TREM2/PLCG2/FGF14/PINK1/EHD3/ANK3/ADRB2/IFNG/S100A1/CACNB2/GAL/CCR2	12
BP	GO:0018958	phenol-containing compound metabolic process	17/2619	103/18670	0.2723	0.4721	0.3541	GCH1/FAH/AKR1B1/DIO3/SNCA/SLC7A11/COMT/MED1/MOXD1/CPQ/HDC/INSM1/SNCAIP/SULT1A2/DIO2/DCT/TH	17
BP	GO:0099643	signal release from synapse	27/2619	170/18670	0.2724	0.4721	0.3541	SLC18A2/TACR2/SNCA/RIMS3/PREPL/PRKCB/SYT11/SYNJ1/PFN2/MCTP1/GSK3B/HRH3/GPER1/SYT17/LIN7B/CHRNA3/PTPRN2/SNCAIP/HCRT/ADCY1/VAMP2/CACNB2/CACNA1D/SYT1/SYN1/RAP1B/NAPA	27
BP	GO:0014888	striated muscle adaptation	10/2619	57/18670	0.2726	0.4721	0.3541	IGFBP5/SMAD3/IL15/CFLAR/EZH2/GTF2IRD1/MYOC/PPP3CA/ATP2B4/CAMK2B	10
BP	GO:0048008	platelet-derived growth factor receptor signaling pathway	10/2619	57/18670	0.2726	0.4721	0.3541	JAK2/SNCA/PLEKHA1/PTPN2/CBLB/PDGFB/VEGFA/HIP1R/SGPL1/LRIG2	10
BP	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	10/2619	57/18670	0.2726	0.4721	0.3541	SRI/MPC2/BAD/EFNA5/ARRB1/OXCT1/LRP5/MAP4K4/ANO1/HIF1A	10
BP	GO:1901799	negative regulation of proteasomal protein catabolic process	10/2619	57/18670	0.2726	0.4721	0.3541	LAMP3/GABARAPL2/UBE2J1/HFE/FHIT/OGT/RYBP/N4BP1/CLEC16A/USP14	10
BP	GO:1903035	negative regulation of response to wounding	15/2619	90/18670	0.276	0.4779	0.3584	PROS1/SMAD3/SERPINE1/APOE/TFPI/CERS2/KLK8/NOS3/CLASP1/PDGFB/EPHA4/KRT1/CDKN1A/SH2B3/LRIG2	15
BP	GO:0040013	negative regulation of locomotion	60/2619	396/18670	0.278	0.4805	0.3604	SLAMF8/ADORA3/SFRP1/PTN/NOTCH1/CD200/IL27RA/IGFBP5/SEMA4D/CXCL13/ABHD6/SEMA4A/SEMA3A/PFN2/MCTP1/CX3CR1/SERPINE1/STC1/ANGPT2/ADA/RAP2C/APOE/LIMCH1/TRIM26/SEMA4C/OSBPL8/WNT11/MAGI2/CSNK2B/PPARG/PTGER4/PTPN2/TIE1/ELANE/KRIT1/CERS2/TRIB1/C5orf30/SEMA3F/TRIM21/TBX5/NBL1/GHSR/CLASP1/PML/PIN1/HMGB1/AP1AR/SEMA3E/PTPRK/NF2/PADI2/TIMP1/ERBB4/FBLN1/TRIM32/COL3A1/HOXA7/ABHD2/SERPINF1	60
BP	GO:0002209	behavioral defense response	7/2619	38/18670	0.279	0.4805	0.3604	BRINP1/USP46/APOE/PENK/DEAF1/VDAC3/EP300	7
BP	GO:0003298	physiological muscle hypertrophy	7/2619	38/18670	0.279	0.4805	0.3604	RGS4/AGT/CTDP1/IGF1/SORBS2/PIN1/AKAP13	7
BP	GO:0003301	physiological cardiac muscle hypertrophy	7/2619	38/18670	0.279	0.4805	0.3604	RGS4/AGT/CTDP1/IGF1/SORBS2/PIN1/AKAP13	7
BP	GO:0006656	phosphatidylcholine biosynthetic process	7/2619	38/18670	0.279	0.4805	0.3604	PEMT/CSNK2B/PCTP/FABP3/LPIN1/STARD7/CHPT1	7
BP	GO:0015682	ferric iron transport	7/2619	38/18670	0.279	0.4805	0.3604	TFRC/ATP6V0D1/HFE/TCIRG1/ATP6V0E2/MCOLN1/RAB11B	7
BP	GO:0015804	neutral amino acid transport	7/2619	38/18670	0.279	0.4805	0.3604	SLC7A5/SLC38A2/SLC38A1/RGS4/NFE2L1/SFXN1/SLC1A1	7
BP	GO:0019068	virion assembly	7/2619	38/18670	0.279	0.4805	0.3604	VPS37C/APOE/PC/CHMP6/CHMP2A/UBB/CHMP1B	7
BP	GO:0046329	negative regulation of JNK cascade	7/2619	38/18670	0.279	0.4805	0.3604	SFRP1/PINK1/DNAJA1/PTPN22/NCOR1/CYLD/TAOK3	7
BP	GO:0046825	regulation of protein export from nucleus	7/2619	38/18670	0.279	0.4805	0.3604	BARD1/GSK3B/TPR/CAMK1/SETD2/GTSE1/TCF7L2	7
BP	GO:0050892	intestinal absorption	7/2619	38/18670	0.279	0.4805	0.3604	KCNQ1/IREB2/UGCG/GCNT3/SLC2A5/TJP2/LIMA1	7
BP	GO:0051590	positive regulation of neurotransmitter transport	7/2619	38/18670	0.279	0.4805	0.3604	TACR2/SNCA/GPER1/VAMP7/CACNB2/CACNA1D/SYT1	7
BP	GO:0060416	response to growth hormone	7/2619	38/18670	0.279	0.4805	0.3604	JAK2/IGFBP5/ASS1/GHSR/CPS1/STAT5A/GHR	7
BP	GO:0061049	cell growth involved in cardiac muscle cell development	7/2619	38/18670	0.279	0.4805	0.3604	RGS4/AGT/CTDP1/IGF1/SORBS2/PIN1/AKAP13	7
BP	GO:0072512	trivalent inorganic cation transport	7/2619	38/18670	0.279	0.4805	0.3604	TFRC/ATP6V0D1/HFE/TCIRG1/ATP6V0E2/MCOLN1/RAB11B	7
BP	GO:0086091	regulation of heart rate by cardiac conduction	7/2619	38/18670	0.279	0.4805	0.3604	SCN1B/KCNQ1/BIN1/KCNJ2/CACNB2/AKAP9/CACNA1D	7
BP	GO:1901021	positive regulation of calcium ion transmembrane transporter activity	7/2619	38/18670	0.279	0.4805	0.3604	ATP1B1/PLCG2/FGF14/EHD3/S100A1/CACNB2/HSPA2	7
BP	GO:1902742	apoptotic process involved in development	7/2619	38/18670	0.279	0.4805	0.3604	NOTCH1/TNFRSF1B/FOXC1/LEF1/CRYAB/JAG2/SIX3	7
BP	GO:1905898	positive regulation of response to endoplasmic reticulum stress	7/2619	38/18670	0.279	0.4805	0.3604	HERPUD1/NCK2/PTPN2/ATF6/EDEM1/XBP1/DDIT3	7
BP	GO:0010771	negative regulation of cell morphogenesis involved in differentiation	16/2619	97/18670	0.2814	0.4843	0.3632	GBP1/SEMA4D/SEMA4A/SEMA3A/FGF13/SEMA4C/EFNA5/YWHAH/POSTN/SEMA3F/TLX2/AP1AR/SEMA3E/PPP3CA/NGFR/FBLN1	16
BP	GO:0060996	dendritic spine development	16/2619	97/18670	0.2814	0.4843	0.3632	DOCK10/BAIAP2/ASAP1/NCK2/ZNF365/APOE/SIPA1L1/PLK2/EPHA4/CAMK1/CDKL5/PAK2/CAPRIN2/C21orf91/CAMK2B/ACTR2	16
BP	GO:0035794	positive regulation of mitochondrial membrane permeability	11/2619	64/18670	0.2814	0.4843	0.3632	EYA2/BAD/GSK3B/GZMB/TMEM14A/PPP1R13B/YWHAH/TP53BP2/ACAA2/HIP1R/ATF2	11
BP	GO:0000731	DNA synthesis involved in DNA repair	9/2619	51/18670	0.2819	0.4844	0.3633	POLD2/RPA1/RPA3/POLD4/UBB/DTL/WRN/UBE2L6/RFC2	9
BP	GO:0019369	arachidonic acid metabolic process	9/2619	51/18670	0.2819	0.4844	0.3633	HPGDS/PTGS1/TBXAS1/MAPK3/EPHX2/PLA2G4C/AKR1C3/PTGDS/CBR1	9
BP	GO:0031103	axon regeneration	9/2619	51/18670	0.2819	0.4844	0.3633	PTN/FOLR1/JAK2/PTPRF/CERS2/KLK8/TSPO/EPHA4/LRIG2	9
BP	GO:0045668	negative regulation of osteoblast differentiation	9/2619	51/18670	0.2819	0.4844	0.3633	SFRP1/NOTCH1/IGFBP5/SEMA4D/SMAD3/LRP5/ID2/ID3/TWIST1	9
BP	GO:0051452	intracellular pH reduction	9/2619	51/18670	0.2819	0.4844	0.3633	SLAMF8/ATP6V0D1/DMXL2/TCIRG1/CLN6/SLC11A1/CA2/ATP6V0E2/RAB20	9
BP	GO:0051496	positive regulation of stress fiber assembly	9/2619	51/18670	0.2819	0.4844	0.3633	SFRP1/SMAD3/PFN2/LIMCH1/WNT11/PPM1E/MYOC/NF2/TAC1	9
BP	GO:0043542	endothelial cell migration	42/2619	273/18670	0.2822	0.4847	0.3635	PTN/NOTCH1/LGMN/PRKD2/FBXW7/CXCL13/ANGPT1/SEMA4A/ADAM17/STC1/ANGPT2/APOE/PRKX/PECAM1/AAMP/BMP4/CSNK2B/PPARG/GPX1/CD40/HSPB1/KRIT1/PLK2/AGT/NOS3/RAB13/FGF18/KDR/PDGFB/VEGFA/PLXND1/P2RX4/HMGB1/SCG2/MAP3K3/HIF1A/EMP2/CIB1/STAT5A/PTK2B/SERPINF1/PIK3CA	42
BP	GO:0006937	regulation of muscle contraction	27/2619	171/18670	0.2831	0.4861	0.3646	SPHK1/ATP1B1/TACR2/SRI/KCNQ1/FGF13/STC1/ADA/KIT/BIN1/HSPB6/EHD3/KCNJ2/MYL3/GPER1/F2R/ADRB2/CHRNA3/GHSR/P2RX4/PLCE1/SOD1/AKAP9/RANGRF/CTTN/FLNA/ATP2B1	27
BP	GO:1903169	regulation of calcium ion transmembrane transport	24/2619	151/18670	0.2861	0.4911	0.3683	CXCL9/DYSF/CXCL10/ATP1B1/PLCG2/SNCA/SRI/CXCL11/FGF14/PRNP/BIN1/EHD3/GPER1/TSPAN13/F2R/S100A1/XCL1/CD19/CALCR/CACNB2/REM1/LIME1/HSPA2/PTK2B	24
BP	GO:0014812	muscle cell migration	17/2619	104/18670	0.2862	0.4911	0.3683	SIX1/PLEKHO1/CCL5/IGFBP5/THBS4/SERPINE1/AAMP/ROCK1/POSTN/TRIB1/AGT/IGF1/PDGFB/NET1/HAS2/PLXNA1/SMO	17
BP	GO:0043583	ear development	34/2619	219/18670	0.2878	0.4917	0.3688	ZIC1/SIX1/NOTCH1/CEBPA/SOX9/MAPK3/NIPBL/KCNQ1/CCNA2/ATP8B1/BMP4/FGF20/KCNK3/FZD3/NAGLU/PRKRA/OSR2/MCOLN3/SIX2/RBPJ/EPHA4/ALDH1A3/LGR5/MAPKAPK2/SOD1/JAG2/MAF/MPV17/CEP290/FZD6/SLC4A7/PSAP/TWIST1/FZD2	34
BP	GO:0001975	response to amphetamine	6/2619	32/18670	0.2879	0.4917	0.3688	SLC18A2/RANBP2/RGS4/PPP3CA/SOD1/TH	6
BP	GO:0033006	regulation of mast cell activation involved in immune response	6/2619	32/18670	0.2879	0.4917	0.3688	IL4R/FGR/FOXF1/RAC2/VAMP7/IL13RA2	6
BP	GO:0039694	viral RNA genome replication	6/2619	32/18670	0.2879	0.4917	0.3688	APOBEC3C/FBXL2/TOP2A/CXCL8/PIK3C2G/HMGA2	6
BP	GO:0042491	inner ear auditory receptor cell differentiation	6/2619	32/18670	0.2879	0.4917	0.3688	NOTCH1/MCOLN3/RBPJ/SOD1/JAG2/SLC4A7	6
BP	GO:0045745	positive regulation of G protein-coupled receptor signaling pathway	6/2619	32/18670	0.2879	0.4917	0.3688	PRMT5/PHB/KLK14/GPER1/TMOD2/FZD2	6
BP	GO:0051385	response to mineralocorticoid	6/2619	32/18670	0.2879	0.4917	0.3688	GPER1/CDKN1A/KRAS/CSN1S1/ATP2B1/TH	6
BP	GO:0055022	negative regulation of cardiac muscle tissue growth	6/2619	32/18670	0.2879	0.4917	0.3688	JARID2/RBP4/RGS4/MAPK11/CTDP1/TBX5	6
BP	GO:0055094	response to lipoprotein particle	6/2619	32/18670	0.2879	0.4917	0.3688	APOE/PPARG/CD81/LPL/MYD88/NPC1	6
BP	GO:0060674	placenta blood vessel development	6/2619	32/18670	0.2879	0.4917	0.3688	ARID1A/RBM15/RBPJ/TMED2/PLCD1/GGNBP2	6
BP	GO:0061117	negative regulation of heart growth	6/2619	32/18670	0.2879	0.4917	0.3688	JARID2/RBP4/RGS4/MAPK11/CTDP1/TBX5	6
BP	GO:0061384	heart trabecula morphogenesis	6/2619	32/18670	0.2879	0.4917	0.3688	NOTCH1/SOS1/RBP4/MED1/S1PR1/RBPJ	6
BP	GO:0099623	regulation of cardiac muscle cell membrane repolarization	6/2619	32/18670	0.2879	0.4917	0.3688	SCN1B/SNTA1/KCNQ1/AKAP9/CACNA1D/FLNA	6
BP	GO:1900745	positive regulation of p38MAPK cascade	6/2619	32/18670	0.2879	0.4917	0.3688	SPHK1/MAP3K5/MFHAS1/VEGFA/MAP3K3/NCF1	6
BP	GO:1902235	regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	6/2619	32/18670	0.2879	0.4917	0.3688	HERPUD1/NCK2/CREB3/PTPN2/XBP1/DDIT3	6
BP	GO:1904467	regulation of tumor necrosis factor secretion	6/2619	32/18670	0.2879	0.4917	0.3688	IL27RA/SYT11/LILRA2/IFNG/GHSR/LPL	6
BP	GO:2000780	negative regulation of double-strand break repair	6/2619	32/18670	0.2879	0.4917	0.3688	SMCHD1/TRIP12/UBQLN4/UBR5/HMGA2/TWIST1	6
BP	GO:0033692	cellular polysaccharide biosynthetic process	12/2619	71/18670	0.2889	0.4933	0.37	PPP1R3C/ENPP1/PGM1/EXT2/GSK3B/INSR/DYRK2/EXTL2/IGF1/HAS2/PASK/SORBS1	12
BP	GO:0042440	pigment metabolic process	12/2619	71/18670	0.2889	0.4933	0.37	FECH/SLC7A11/BDH2/ADA/IREB2/UROD/UROS/TSPO/NFE2L1/DCT/CPOX/PRPS1	12
BP	GO:0031623	receptor internalization	18/2619	111/18670	0.2905	0.4958	0.3719	TFRC/PLCG2/ANGPT1/SNCA/USP46/LRPAP1/EGF/NTF3/AP2M1/HTR2B/MAGI2/SELE/ARRB1/CD81/CD63/VEGFA/CXCR2/CXCL8	18
BP	GO:0045638	negative regulation of myeloid cell differentiation	15/2619	91/18670	0.2909	0.4963	0.3722	NFKBIA/SFRP1/FBXW7/TCTA/WDR61/GPR171/PTPN2/TRIB1/RBM15/HMGB3/MYC/HOXA5/CIB1/PTK2B/HOXA7	15
BP	GO:0051899	membrane depolarization	15/2619	91/18670	0.2909	0.4963	0.3722	SCN1B/GOT1/KCNJ2/ANK3/YWHAH/TSPO/KDR/MYOC/P2RX4/CACNB2/RANGRF/SCN9A/CACNA1D/NEDD4L/SCN3A	15
BP	GO:0030520	intracellular estrogen receptor signaling pathway	10/2619	58/18670	0.2914	0.4967	0.3725	AR/UFSP2/NCOA6/TADA3/CYP7B1/MED1/ARID1A/TAF7/PADI2/KANK2	10
BP	GO:0030837	negative regulation of actin filament polymerization	10/2619	58/18670	0.2914	0.4967	0.3725	TMOD1/PFN2/CAPZA1/BBS4/TMOD2/FHOD3/SCIN/TMSB10/HIP1R/ARFGEF1	10
BP	GO:0098930	axonal transport	10/2619	58/18670	0.2914	0.4967	0.3725	UCHL1/BLOC1S1/TRAK1/HSPB1/KIF5C/KIF4A/DYNC1H1/SOD1/SPAST/HIF1A	10
BP	GO:0010569	regulation of double-strand break repair via homologous recombination	8/2619	45/18670	0.2919	0.4969	0.3727	SMCHD1/CHEK1/ZNF365/MMS19/UBQLN4/TIMELESS/SETD2/ACTR2	8
BP	GO:0031018	endocrine pancreas development	8/2619	45/18670	0.2919	0.4969	0.3727	SOX9/BAD/GSK3B/BMP4/INSM1/IL6/IL6R/SMO	8
BP	GO:0032570	response to progesterone	8/2619	45/18670	0.2919	0.4969	0.3727	PTN/CD38/GABRB1/BAD/TSPO/TYMS/CSN1S1/ABHD2	8
BP	GO:0048483	autonomic nervous system development	8/2619	45/18670	0.2919	0.4969	0.3727	SIX1/SEMA3A/FZD3/NTRK1/SEMA3F/INSM1/TLX2/PHACTR4	8
BP	GO:0031032	actomyosin structure organization	31/2619	199/18670	0.292	0.497	0.3728	SFRP1/ECT2/EPB41L1/SMAD3/TMOD1/CFLAR/PFN2/RACGAP1/CORO2B/LIMCH1/MYOM2/WNT11/ROCK1/BBS4/PTGER4/NEBL/ARRB1/S1PR1/PPM1E/TMOD2/CLASP1/FHOD3/MYOC/ALMS1/NF2/TAC1/AKAP13/ITGB5/PTK2B/MYH10/SORBS1	31
BP	GO:0006813	potassium ion transport	37/2619	240/18670	0.2927	0.498	0.3735	ATP1B1/TREM2/KCNN3/FXYD1/SLC12A8/KCNQ1/KCNK15/NETO2/PRNP/SLC12A7/BIN1/MTMR6/KCNK3/KLHL24/KCNJ2/ANK3/RGS4/CD63/NOS3/HCRT/ABCC8/PKD2L1/VAMP2/KCNJ8/KCNN2/AKAP9/CACNA1D/GAL/CCT8L2/KCND1/FLNA/KCNQ3/PTK2B/ATF4/KCNMB2/NEDD4L/DPP6	37
BP	GO:0030433	ubiquitin-dependent ERAD pathway	13/2619	78/18670	0.2954	0.5021	0.3766	HERPUD1/ERLIN2/UBE2J1/DNAJB14/FBXO17/UBXN4/ANKZF1/MAN1B1/EDEM1/UBXN8/HSPA5/SEL1L/USP14	13
BP	GO:0072347	response to anesthetic	13/2619	78/18670	0.2954	0.5021	0.3766	SNCA/CCNA2/ADA/PENK/PEA15/CXCR4/RGS4/CRHBP/SRR/TAC1/HNMT/PTK2B/HSPA5	13
BP	GO:1903313	positive regulation of mRNA metabolic process	13/2619	78/18670	0.2954	0.5021	0.3766	CIRBP/FTO/PRDX6/ZC3HAV1/ROCK1/PRR5L/CCNB1/POLR2G/ZFP36L2/NCBP2/DAZAP1/HNRNPD/NUP98	13
BP	GO:0008361	regulation of cell size	28/2619	179/18670	0.2962	0.5021	0.3766	SEMA4D/SLC12A8/MACF1/IL7R/SEMA4A/SEMA3A/FGF13/DEPTOR/SLC12A7/APOE/GSK3B/CDK4/SEMA4C/EFNA5/WDTC1/SEMA3F/RND2/VEGFA/SEMA3E/ANXA7/CTTN/GOLGA4/TRPV2/CREB1/CDKL5/CYFIP1/DSCAM/BDNF	28
BP	GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin	5/2619	26/18670	0.2968	0.5021	0.3766	CPA3/CMA1/F2R/AGT/CTSG	5
BP	GO:0006700	C21-steroid hormone biosynthetic process	5/2619	26/18670	0.2968	0.5021	0.3766	AKR1B1/FDX1/CYP11A1/TSPO/EGR1	5
BP	GO:0006817	phosphate ion transport	5/2619	26/18670	0.2968	0.5021	0.3766	ANKH/SLC20A2/ADAMTS8/CEBPB/ATF4	5
BP	GO:0010460	positive regulation of heart rate	5/2619	26/18670	0.2968	0.5021	0.3766	GCH1/KCNQ1/ADA/RGS4/SLC1A1	5
BP	GO:0022011	myelination in peripheral nervous system	5/2619	26/18670	0.2968	0.5021	0.3766	NTRK2/ADAM22/MYOC/SOD1/FA2H	5
BP	GO:0032292	peripheral nervous system axon ensheathment	5/2619	26/18670	0.2968	0.5021	0.3766	NTRK2/ADAM22/MYOC/SOD1/FA2H	5
BP	GO:0032957	inositol trisphosphate metabolic process	5/2619	26/18670	0.2968	0.5021	0.3766	PLCG2/GPER1/PLCE1/PLCD1/PTK2B	5
BP	GO:0042745	circadian sleep/wake cycle	5/2619	26/18670	0.2968	0.5021	0.3766	ADA/HCRTR2/PTGDS/AHCY/TH	5
BP	GO:0043090	amino acid import	5/2619	26/18670	0.2968	0.5021	0.3766	SLC7A11/RGS4/AGT/ARL6IP5/SLC1A1	5
BP	GO:0048169	regulation of long-term neuronal synaptic plasticity	5/2619	26/18670	0.2968	0.5021	0.3766	SNCA/KIT/AGT/KRAS/CAMK2B	5
BP	GO:0051875	pigment granule localization	5/2619	26/18670	0.2968	0.5021	0.3766	MREG/RAB27A/BBS4/DCTN2/RAB11B	5
BP	GO:0071377	cellular response to glucagon stimulus	5/2619	26/18670	0.2968	0.5021	0.3766	PRKAR2A/ASS1/ADCY1/CPS1/ADCY2	5
BP	GO:0071711	basement membrane organization	5/2619	26/18670	0.2968	0.5021	0.3766	CMA1/PXDN/CLASP1/FERMT1/COL4A1	5
BP	GO:0080111	DNA demethylation	5/2619	26/18670	0.2968	0.5021	0.3766	FTO/TDG/APOBEC3C/APOBEC3B/USP9X	5
BP	GO:0097066	response to thyroid hormone	5/2619	26/18670	0.2968	0.5021	0.3766	SIX1/AKR1B1/KIT/MED1/GHSR	5
BP	GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	5/2619	26/18670	0.2968	0.5021	0.3766	BAD/GZMB/PPP1R13B/YWHAH/TP53BP2	5
BP	GO:1900740	positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	5/2619	26/18670	0.2968	0.5021	0.3766	BAD/GZMB/PPP1R13B/YWHAH/TP53BP2	5
BP	GO:1903959	regulation of anion transmembrane transport	5/2619	26/18670	0.2968	0.5021	0.3766	PRNP/RGS4/AGT/ARL6IP5/ABCB1	5
BP	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	20/2619	125/18670	0.2979	0.5039	0.3779	BTN2A2/RFWD3/CRADD/CHEK2/EZH2/ATM/CDKN2C/CDK4/CTDSPL/MYO16/PLK2/CCNB1/PML/GTSE1/CDK1/CDKN1A/WEE1/EP300/KANK2/RBL2	20
BP	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	11/2619	65/18670	0.2993	0.5058	0.3794	CELF2/MBNL3/SART3/FAM172A/CELF1/RBM15/SRSF4/HNRNPA1/SRSF8/RBM19/SREK1	11
BP	GO:0048663	neuron fate commitment	11/2619	65/18670	0.2993	0.5058	0.3794	SIX1/NOTCH1/HOXC10/BCL11B/BMP4/EVX1/RBPJ/JAG2/OLIG2/ID2/SATB2	11
BP	GO:0051187	cofactor catabolic process	11/2619	65/18670	0.2993	0.5058	0.3794	SNCA/GPX3/PRDX6/PXDN/GPX1/CAT/ACAT1/AHCY/CYP4F11/HBB/PRDX2	11
BP	GO:0007009	plasma membrane organization	17/2619	105/18670	0.3002	0.507	0.3803	MICALL1/DYSF/AR/CLU/SYT11/PTPRC/BAIAP2/ASAP1/BIN1/ANK3/UGCG/CXCR4/PLSCR4/SOD1/FA2H/PSAP/MYH10	17
BP	GO:0032006	regulation of TOR signaling	17/2619	105/18670	0.3002	0.507	0.3803	SIK1/TREM2/UBR2/DDIT4/ATM/DEPTOR/RRAGA/SEC13/LAMTOR2/MLST8/HIF1A/PRKAA1/RRAGD/GOLPH3/SESN1/CLEC16A/PIK3CA	17
BP	GO:0002377	immunoglobulin production	30/2619	193/18670	0.3003	0.507	0.3803	PARP3/TFRC/IL27RA/ERCC1/NBN/IL7R/IL4R/PTPRC/ATM/RBP4/THOC1/HLA-E/IGLV1-44/LAX1/SAMHD1/CD28/CD40/GCNT3/TCIRG1/MZB1/IL6/XCL1/HLA-DQB1/PMS2P1/TNFSF4/BATF/TCF3/XBP1/IL13RA2/CD40LG	30
BP	GO:0050885	neuromuscular process controlling balance	9/2619	52/18670	0.3021	0.5097	0.3823	GPR88/NBN/CAMTA1/HERC1/GM2A/ALDH1A3/GAA/PSAP/MYH10	9
BP	GO:2000677	regulation of transcription regulatory region DNA binding	9/2619	52/18670	0.3021	0.5097	0.3823	FBXW7/SRI/FOXC1/IFNG/IGF1/EP300/HMGA2/DDIT3/TWIST1	9
BP	GO:0042391	regulation of membrane potential	65/2619	434/18670	0.3022	0.5097	0.3823	PTN/SCN1B/ATP1B1/TREM2/SNTA1/FXYD1/GPR88/SNCA/SRI/RIMS3/KCNQ1/SH3GL1/GOT1/KCNK15/FGF14/PID1/FGF13/GABRB1/BAD/BAIAP2/PINK1/NTRK2/GSK3B/BIN1/EHD3/GABRA4/KCNK3/KCNJ2/ANK3/GPER1/ADRB2/YWHAH/TUSC2/RGS4/CHRNA3/DLD/TSPO/KDR/HCRT/MYOC/P2RX4/UBB/ARL6IP5/CHRNB1/PPP3CA/CACNB2/KCNJ8/SOD1/KCNN2/AKAP9/RANGRF/SCN9A/TAC1/CACNA1D/GABBR1/CXADR/PYCR1/FLNA/KCNQ3/PTK2B/STOML2/KCNMB2/NEDD4L/SCN3A/PPA2	65
BP	GO:0010661	positive regulation of muscle cell apoptotic process	7/2619	39/18670	0.3024	0.5097	0.3823	MAP3K5/PPARG/ARRB1/IFNG/AGT/CXCR2/ATF4	7
BP	GO:0030204	chondroitin sulfate metabolic process	7/2619	39/18670	0.3024	0.5097	0.3823	NDNF/HEXA/CHST15/SPOCK2/VCAN/CHST12/ARSB	7
BP	GO:0030488	tRNA methylation	7/2619	39/18670	0.3024	0.5097	0.3823	HSD17B10/METTL8/TARBP1/TRMT112/TRMT5/NSUN6/TRMT13	7
BP	GO:0032692	negative regulation of interleukin-1 production	7/2619	39/18670	0.3024	0.5097	0.3823	TNFAIP3/TREM2/CX3CR1/CARD8/IGF1/GHSR/PML	7
BP	GO:0014902	myotube differentiation	18/2619	112/18670	0.3041	0.5109	0.3832	SIX1/CXCL9/SIK1/CXCL10/NOTCH1/PLEKHO1/IL4R/CFLAR/GPX1/MAML1/CD81/IGF1/SORT1/PPP3CA/TNFSF14/XBP1/SMO/BDNF	18
BP	GO:0015918	sterol transport	18/2619	112/18670	0.3041	0.5109	0.3832	NFKBIA/LIPC/CLU/OSBPL3/APOM/GRAMD1C/EGF/APOE/OSBPL8/PPARG/NFKB1/APOC1/TSPO/NR1H2/SCP2/ABCA2/LIMA1/NPC1	18
BP	GO:0043279	response to alkaloid	18/2619	112/18670	0.3041	0.5109	0.3832	SNCA/CCNA2/ADA/PENK/PEA15/PPARG/CXCR4/RGS4/CRHBP/SRR/TMED10/PRKAA1/TAC1/HNMT/PTK2B/UQCRC1/HSPA5/TH	18
BP	GO:0007620	copulation	4/2619	20/18670	0.3054	0.5109	0.3832	DDO/ADA/KLK14/TAC1	4
BP	GO:0010042	response to manganese ion	4/2619	20/18670	0.3054	0.5109	0.3832	TSPO/ATF4/HSPA5/TH	4
BP	GO:0031061	negative regulation of histone methylation	4/2619	20/18670	0.3054	0.5109	0.3832	MTF2/JARID2/DNMT1/KDM3A	4
BP	GO:0034393	positive regulation of smooth muscle cell apoptotic process	4/2619	20/18670	0.3054	0.5109	0.3832	PPARG/ARRB1/IFNG/ATF4	4
BP	GO:0042228	interleukin-8 biosynthetic process	4/2619	20/18670	0.3054	0.5109	0.3832	ELANE/NOD1/BCL10/TLR8	4
BP	GO:0042276	error-prone translesion synthesis	4/2619	20/18670	0.3054	0.5109	0.3832	RPA1/RPA3/UBB/RFC2	4
BP	GO:0043369	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment	4/2619	20/18670	0.3054	0.5109	0.3832	LY9/IL6/BATF/CYLD	4
BP	GO:0043691	reverse cholesterol transport	4/2619	20/18670	0.3054	0.5109	0.3832	LIPC/CLU/APOM/APOE	4
BP	GO:0046514	ceramide catabolic process	4/2619	20/18670	0.3054	0.5109	0.3832	ASAH1/GM2A/NEU1/PSAP	4
BP	GO:0048745	smooth muscle tissue development	4/2619	20/18670	0.3054	0.5109	0.3832	SIX1/SOX9/BMP4/COL3A1	4
BP	GO:0051797	regulation of hair follicle development	4/2619	20/18670	0.3054	0.5109	0.3832	DKK4/FERMT1/GAL/SMO	4
BP	GO:0060602	branch elongation of an epithelium	4/2619	20/18670	0.3054	0.5109	0.3832	SIX1/SOX9/BMP4/MED1	4
BP	GO:0070828	heterochromatin organization	4/2619	20/18670	0.3054	0.5109	0.3832	SMCHD1/TPR/HMGA1/HMGA2	4
BP	GO:0070987	error-free translesion synthesis	4/2619	20/18670	0.3054	0.5109	0.3832	RPA1/RPA3/UBB/RFC2	4
BP	GO:0086014	atrial cardiac muscle cell action potential	4/2619	20/18670	0.3054	0.5109	0.3832	KCNQ1/CACNB2/KCNN2/FLNA	4
BP	GO:0086026	atrial cardiac muscle cell to AV node cell signaling	4/2619	20/18670	0.3054	0.5109	0.3832	KCNQ1/CACNB2/KCNN2/FLNA	4
BP	GO:0086066	atrial cardiac muscle cell to AV node cell communication	4/2619	20/18670	0.3054	0.5109	0.3832	KCNQ1/CACNB2/KCNN2/FLNA	4
BP	GO:0097062	dendritic spine maintenance	4/2619	20/18670	0.3054	0.5109	0.3832	PRNP/APOE/INSR/CTTN	4
BP	GO:0097734	extracellular exosome biogenesis	4/2619	20/18670	0.3054	0.5109	0.3832	RAB27A/SDC1/IFNG/CHMP2A	4
BP	GO:0098780	response to mitochondrial depolarisation	4/2619	20/18670	0.3054	0.5109	0.3832	VPS13C/PINK1/ATG13/OPTN	4
BP	GO:1900017	positive regulation of cytokine production involved in inflammatory response	4/2619	20/18670	0.3054	0.5109	0.3832	NOD2/IL17RC/MYD88/IL17RA	4
BP	GO:1903204	negative regulation of oxidative stress-induced neuron death	4/2619	20/18670	0.3054	0.5109	0.3832	SLC7A11/PINK1/HIF1A/ATF4	4
BP	GO:1903599	positive regulation of autophagy of mitochondrion	4/2619	20/18670	0.3054	0.5109	0.3832	VPS13C/PINK1/OPTN/HIF1A	4
BP	GO:1905523	positive regulation of macrophage migration	4/2619	20/18670	0.3054	0.5109	0.3832	TREM2/CCL5/MAPK3/P2RX4	4
BP	GO:2000774	positive regulation of cellular senescence	4/2619	20/18670	0.3054	0.5109	0.3832	HLA-G/KRAS/HMGA1/HMGA2	4
BP	GO:1903051	negative regulation of proteolysis involved in cellular protein catabolic process	12/2619	72/18670	0.3061	0.5119	0.3839	LAMP3/GABARAPL2/UBE2J1/HFE/FHIT/PML/EPHA4/OGT/RYBP/N4BP1/CLEC16A/USP14	12
BP	GO:0032890	regulation of organic acid transport	10/2619	59/18670	0.3105	0.5147	0.386	SNCA/TNFRSF11A/HRH3/RGS4/AGT/P2RX4/PLA2R1/ARL6IP5/NCOR1/FABP3	10
BP	GO:1902369	negative regulation of RNA catabolic process	10/2619	59/18670	0.3105	0.5147	0.386	CIRBP/HNRNPA0/SLC11A1/MAPKAPK2/DND1/YBX1/TARDBP/MYD88/HNRNPD/DAZL	10
BP	GO:0018107	peptidyl-threonine phosphorylation	20/2619	126/18670	0.3109	0.5147	0.386	SPHK1/CDC7/PRKD2/RIPK2/TBK1/PRKCB/DDIT4/CHEK1/DYRK4/EGF/GSK3B/DYRK2/CSNK2B/ROCK1/VRK2/CSNK1A1/CSNK1E/NLK/CDK1/CLK1	20
BP	GO:0002834	regulation of response to tumor cell	3/2619	14/18670	0.3122	0.5147	0.386	CRTAM/HMGB1/FBXO38	3
BP	GO:0002837	regulation of immune response to tumor cell	3/2619	14/18670	0.3122	0.5147	0.386	CRTAM/HMGB1/FBXO38	3
BP	GO:0003128	heart field specification	3/2619	14/18670	0.3122	0.5147	0.386	SMARCD3/BMP4/RBPJ	3
BP	GO:0003188	heart valve formation	3/2619	14/18670	0.3122	0.5147	0.386	NOTCH1/SOX9/TWIST1	3
BP	GO:0007501	mesodermal cell fate specification	3/2619	14/18670	0.3122	0.5147	0.386	HOXA11/EYA2/SIX2	3
BP	GO:0009071	serine family amino acid catabolic process	3/2619	14/18670	0.3122	0.5147	0.386	CBS/SDS/THNSL2	3
BP	GO:0010421	hydrogen peroxide-mediated programmed cell death	3/2619	14/18670	0.3122	0.5147	0.386	HGF/PINK1/TRAP1	3
BP	GO:0010935	regulation of macrophage cytokine production	3/2619	14/18670	0.3122	0.5147	0.386	IRAK3/HLA-G/CUEDC2	3
BP	GO:0014854	response to inactivity	3/2619	14/18670	0.3122	0.5147	0.386	SGCA/MTMR4/CAT	3
BP	GO:0018410	C-terminal protein amino acid modification	3/2619	14/18670	0.3122	0.5147	0.386	AGTPBP1/LCMT1/ATG12	3
BP	GO:0020027	hemoglobin metabolic process	3/2619	14/18670	0.3122	0.5147	0.386	EPB42/CAT/HIF1A	3
BP	GO:0021535	cell migration in hindbrain	3/2619	14/18670	0.3122	0.5147	0.386	SEMA4C/LEF1/FLNA	3
BP	GO:0021692	cerebellar Purkinje cell layer morphogenesis	3/2619	14/18670	0.3122	0.5147	0.386	RORA/AGTPBP1/HERC1	3
BP	GO:0021781	glial cell fate commitment	3/2619	14/18670	0.3122	0.5147	0.386	SOX9/NFE2L1/OLIG2	3
BP	GO:0030207	chondroitin sulfate catabolic process	3/2619	14/18670	0.3122	0.5147	0.386	HEXA/VCAN/ARSB	3
BP	GO:0031272	regulation of pseudopodium assembly	3/2619	14/18670	0.3122	0.5147	0.386	CDC42EP3/KIT/CCR7	3
BP	GO:0032310	prostaglandin secretion	3/2619	14/18670	0.3122	0.5147	0.386	ABCC4/TNFRSF11A/P2RX4	3
BP	GO:0034370	triglyceride-rich lipoprotein particle remodeling	3/2619	14/18670	0.3122	0.5147	0.386	LIPC/APOE/LPL	3
BP	GO:0035020	regulation of Rac protein signal transduction	3/2619	14/18670	0.3122	0.5147	0.386	AUTS2/OGT/KRAS	3
BP	GO:0035358	regulation of peroxisome proliferator activated receptor signaling pathway	3/2619	14/18670	0.3122	0.5147	0.386	LMO3/ASXL2/TWIST1	3
BP	GO:0035435	phosphate ion transmembrane transport	3/2619	14/18670	0.3122	0.5147	0.386	ANKH/SLC20A2/ADAMTS8	3
BP	GO:0035791	platelet-derived growth factor receptor-beta signaling pathway	3/2619	14/18670	0.3122	0.5147	0.386	PTPN2/PDGFB/HIP1R	3
BP	GO:0036295	cellular response to increased oxygen levels	3/2619	14/18670	0.3122	0.5147	0.386	ATP6V0D1/FAS/PPARG	3
BP	GO:0040034	regulation of development, heterochronic	3/2619	14/18670	0.3122	0.5147	0.386	NOTCH1/GDPD5/RBPJ	3
BP	GO:0042487	regulation of odontogenesis of dentin-containing tooth	3/2619	14/18670	0.3122	0.5147	0.386	TNFRSF11B/BMP4/MMP20	3
BP	GO:0043173	nucleotide salvage	3/2619	14/18670	0.3122	0.5147	0.386	ADK/ADA/AMPD3	3
BP	GO:0043558	regulation of translational initiation in response to stress	3/2619	14/18670	0.3122	0.5147	0.386	NCK2/DNAJC3/ATF4	3
BP	GO:0045064	T-helper 2 cell differentiation	3/2619	14/18670	0.3122	0.5147	0.386	IL4R/TNFSF4/BATF	3
BP	GO:0045346	regulation of MHC class II biosynthetic process	3/2619	14/18670	0.3122	0.5147	0.386	JAK2/IFNG/XBP1	3
BP	GO:0045953	negative regulation of natural killer cell mediated cytotoxicity	3/2619	14/18670	0.3122	0.5147	0.386	HLA-F/HLA-G/HLA-E	3
BP	GO:0046133	pyrimidine ribonucleoside catabolic process	3/2619	14/18670	0.3122	0.5147	0.386	ENTPD4/APOBEC3C/APOBEC3B	3
BP	GO:0046479	glycosphingolipid catabolic process	3/2619	14/18670	0.3122	0.5147	0.386	GM2A/NEU1/PSAP	3
BP	GO:0046606	negative regulation of centrosome cycle	3/2619	14/18670	0.3122	0.5147	0.386	MDM1/CHMP2A/KAT2B	3
BP	GO:0046940	nucleoside monophosphate phosphorylation	3/2619	14/18670	0.3122	0.5147	0.386	AK1/AK6/RAD50	3
BP	GO:0051712	positive regulation of killing of cells of other organism	3/2619	14/18670	0.3122	0.5147	0.386	BAD/PRF1/IFNG	3
BP	GO:0051938	L-glutamate import	3/2619	14/18670	0.3122	0.5147	0.386	SLC7A11/ARL6IP5/SLC1A1	3
BP	GO:0055064	chloride ion homeostasis	3/2619	14/18670	0.3122	0.5147	0.386	SLC12A8/CA12/SLC12A7	3
BP	GO:0060049	regulation of protein glycosylation	3/2619	14/18670	0.3122	0.5147	0.386	IL15/TMEM59/ARFGEF1	3
BP	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway	3/2619	14/18670	0.3122	0.5147	0.386	JAK2/STAT5A/GHR	3
BP	GO:0060732	positive regulation of inositol phosphate biosynthetic process	3/2619	14/18670	0.3122	0.5147	0.386	SNCA/PTH1R/GPER1	3
BP	GO:0071361	cellular response to ethanol	3/2619	14/18670	0.3122	0.5147	0.386	ITPR2/PRKAA1/CCL7	3
BP	GO:0071391	cellular response to estrogen stimulus	3/2619	14/18670	0.3122	0.5147	0.386	SFRP1/CRHBP/TRIM24	3
BP	GO:0072216	positive regulation of metanephros development	3/2619	14/18670	0.3122	0.5147	0.386	MYC/EGR1/PDGFB	3
BP	GO:0090151	establishment of protein localization to mitochondrial membrane	3/2619	14/18670	0.3122	0.5147	0.386	NDUFA13/TIMM10/SAMM50	3
BP	GO:0097468	programmed cell death in response to reactive oxygen species	3/2619	14/18670	0.3122	0.5147	0.386	HGF/PINK1/TRAP1	3
BP	GO:1901213	regulation of transcription from RNA polymerase II promoter involved in heart development	3/2619	14/18670	0.3122	0.5147	0.386	NOTCH1/BMP4/RBPJ	3
BP	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	3/2619	14/18670	0.3122	0.5147	0.386	SFRP1/ATF3/PEA15	3
BP	GO:1902570	protein localization to nucleolus	3/2619	14/18670	0.3122	0.5147	0.386	NMD3/NOL8/WRN	3
BP	GO:1903624	regulation of DNA catabolic process	3/2619	14/18670	0.3122	0.5147	0.386	ATM/APAF1/IL6	3
BP	GO:1904748	regulation of apoptotic process involved in development	3/2619	14/18670	0.3122	0.5147	0.386	NOTCH1/TNFRSF1B/FOXC1	3
BP	GO:1904923	regulation of autophagy of mitochondrion in response to mitochondrial depolarization	3/2619	14/18670	0.3122	0.5147	0.386	VPS13C/PINK1/OPTN	3
BP	GO:2001212	regulation of vasculogenesis	3/2619	14/18670	0.3122	0.5147	0.386	TMEM100/KDR/EMP2	3
BP	GO:0001504	neurotransmitter uptake	8/2619	46/18670	0.3137	0.5151	0.3863	SLC18A2/SNCA/SLC29A1/SLC7A11/SLC38A1/RGS4/ARL6IP5/SLC1A1	8
BP	GO:0002067	glandular epithelial cell differentiation	8/2619	46/18670	0.3137	0.5151	0.3863	NOTCH1/BAD/GSK3B/RXRA/BMP4/INSM1/HOXA5/SMO	8
BP	GO:0002715	regulation of natural killer cell mediated immunity	8/2619	46/18670	0.3137	0.5151	0.3863	RASGRP1/HLA-F/HLA-G/MICB/HLA-E/CD96/CRTAM/ULBP2	8
BP	GO:0030490	maturation of SSU-rRNA	8/2619	46/18670	0.3137	0.5151	0.3863	UTP6/DDX52/TSR2/RPS8/HEATR1/MRPS11/RIOK3/TSR3	8
BP	GO:0043300	regulation of leukocyte degranulation	8/2619	46/18670	0.3137	0.5151	0.3863	HLA-F/IL4R/FGR/FOXF1/RAC2/VAMP7/IL13RA2/CCR2	8
BP	GO:0050919	negative chemotaxis	8/2619	46/18670	0.3137	0.5151	0.3863	SEMA4D/UNC5C/SEMA4A/SEMA3A/SEMA4C/EFNA5/SEMA3F/SEMA3E	8
BP	GO:0009303	rRNA transcription	6/2619	33/18670	0.3138	0.5151	0.3863	DDX11/POLR1B/ANG/NPM3/SIRT7/GTF3C5	6
BP	GO:0010039	response to iron ion	6/2619	33/18670	0.3138	0.5151	0.3863	SNCA/HFE/CYBRD1/CCNB1/HIF1A/CPOX	6
BP	GO:0018279	protein N-linked glycosylation via asparagine	6/2619	33/18670	0.3138	0.5151	0.3863	UBE2J1/DPM3/DAD1/FUT8/DDOST/ASGR1	6
BP	GO:0030851	granulocyte differentiation	6/2619	33/18670	0.3138	0.5151	0.3863	CEBPA/LBR/CBFA2T3/LEF1/DHRS7B/TRIB1	6
BP	GO:0040001	establishment of mitotic spindle localization	6/2619	33/18670	0.3138	0.5151	0.3863	NDE1/NUSAP1/ARHGEF2/NDC80/CLASP1/KPNB1	6
BP	GO:0042755	eating behavior	6/2619	33/18670	0.3138	0.5151	0.3863	UCHL1/RMI1/HCRT/GHSR/AGRP/TH	6
BP	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	6/2619	33/18670	0.3138	0.5151	0.3863	TNFAIP3/CEBPA/CDKN2C/CDKN1C/KAT2B/CDKN1A	6
BP	GO:0048854	brain morphogenesis	6/2619	33/18670	0.3138	0.5151	0.3863	CDH2/SOS1/FZD3/BBS4/FZD6/SMO	6
BP	GO:1901797	negative regulation of signal transduction by p53 class mediator	6/2619	33/18670	0.3138	0.5151	0.3863	ING2/CD44/TAF9B/PSMD10/TWIST1/RNF34	6
BP	GO:2001038	regulation of cellular response to drug	6/2619	33/18670	0.3138	0.5151	0.3863	HGF/PINK1/TRAP1/PYCR1/PSAP/HMGA2	6
BP	GO:0006414	translational elongation	21/2619	133/18670	0.3139	0.5151	0.3863	LTN1/MRPL24/MRPL11/MRPL40/MRPL23/SECISBP2L/GFM1/DIO2/MRPS33/MRPS28/MRPS17/MRPS22/MRPS11/GTPBP2/MRPL17/MRPL20/MRPL18/MRPS14/DNAJC24/MRPL4/NEMF	21
BP	GO:0021510	spinal cord development	17/2619	106/18670	0.3144	0.5158	0.3869	ZIC1/PTN/NOTCH1/TCTN1/HOXC10/GDPD5/EVX1/MPST/PTBP2/EED/NFE2L1/ERCC2/ZC4H2/OLIG2/SMO/PLXDC1/PBX3	17
BP	GO:0006303	double-strand break repair via nonhomologous end joining	14/2619	86/18670	0.317	0.5197	0.3898	PARP3/SMCHD1/DCLRE1C/ERCC1/NBN/KDM2A/ATM/BARD1/UVRAG/SETMAR/RAD50/KAT5/BABAM1/HMGA2	14
BP	GO:1903363	negative regulation of cellular protein catabolic process	14/2619	86/18670	0.317	0.5197	0.3898	NELL1/LAMP3/GABARAPL2/ATRAID/UBE2J1/HFE/FHIT/PML/EPHA4/OGT/RYBP/N4BP1/CLEC16A/USP14	14
BP	GO:0046888	negative regulation of hormone secretion	11/2619	66/18670	0.3175	0.5205	0.3904	SFRP1/TACR2/RAB11FIP1/HADH/CRHBP/MAP4K4/GHSR/PPP3CA/NMB/CRY1/INHBB	11
BP	GO:0010565	regulation of cellular ketone metabolic process	28/2619	181/18670	0.3179	0.5209	0.3907	PDK2/SNCA/ERLIN2/SLC7A11/PSMB9/COMT/NQO1/GSTZ1/PSMC2/PPARG/APOC1/PSMB6/WDTC1/PSMC3/NR1H2/GHSR/EGR1/AKR1C3/PDK1/PSMD8/PSMB5/NFE2L1/PSMD10/ATP2B4/EIF6/FABP3/OAZ3/TWIST1	28
BP	GO:0010594	regulation of endothelial cell migration	35/2619	229/18670	0.3183	0.5214	0.3911	PTN/NOTCH1/LGMN/PRKD2/FBXW7/CXCL13/ANGPT1/SEMA4A/ADAM17/STC1/ANGPT2/APOE/AAMP/BMP4/CSNK2B/PPARG/CD40/HSPB1/KRIT1/PLK2/AGT/NOS3/FGF18/KDR/PDGFB/VEGFA/P2RX4/HMGB1/MAP3K3/HIF1A/EMP2/CIB1/STAT5A/PTK2B/SERPINF1	35
BP	GO:0007131	reciprocal meiotic recombination	9/2619	53/18670	0.3226	0.5277	0.3958	KLHDC3/UBR2/ATM/RMI1/RAD51C/RAD50/TOP2A/C11orf80/RAD51B	9
BP	GO:0031638	zymogen activation	9/2619	53/18670	0.3226	0.5277	0.3958	LGMN/RIPK2/BAD/SERPINE1/ASPH/CYFIP2/DHCR24/CIDEB/IFI16	9
BP	GO:0032964	collagen biosynthetic process	9/2619	53/18670	0.3226	0.5277	0.3958	GOT1/BMP4/RCN3/PPARG/F2R/IL6/SUCO/ADAMTS3/LARP6	9
BP	GO:0045851	pH reduction	9/2619	53/18670	0.3226	0.5277	0.3958	SLAMF8/ATP6V0D1/DMXL2/TCIRG1/CLN6/SLC11A1/CA2/ATP6V0E2/RAB20	9
BP	GO:1902475	L-alpha-amino acid transmembrane transport	9/2619	53/18670	0.3226	0.5277	0.3958	SLC7A5/PRAF2/SLC7A11/SLC7A6/SLC38A1/RGS4/AGT/ARL6IP5/SLC1A1	9
BP	GO:1903307	positive regulation of regulated secretory pathway	9/2619	53/18670	0.3226	0.5277	0.3958	HLA-F/RAB27A/IL4R/FGR/VAMP7/CACNB2/CACNA1D/SYT1/RAB15	9
BP	GO:0003208	cardiac ventricle morphogenesis	12/2619	73/18670	0.3235	0.529	0.3968	NOTCH1/FOXC1/SMARCD3/RXRA/MED1/MYL3/FOXF1/ZFPM2/TBX5/RBPJ/CPE/HIF1A	12
BP	GO:0022600	digestive system process	16/2619	100/18670	0.3253	0.5308	0.3981	SOX9/KCNQ1/SERPINA3/RBP4/IREB2/TYMP/UGCG/GCNT3/GHSR/SLC2A5/NOD2/SNX10/TAC1/TJP2/HIP1R/LIMA1	16
BP	GO:0000188	inactivation of MAPK activity	5/2619	27/18670	0.326	0.5308	0.3981	DUSP5/DUSP6/LAX1/RGS4/DUSP2	5
BP	GO:0002026	regulation of the force of heart contraction	5/2619	27/18670	0.326	0.5308	0.3981	MYL3/NOS3/MYL4/GAA/ATP2B4	5
BP	GO:0006706	steroid catabolic process	5/2619	27/18670	0.326	0.5308	0.3981	APOE/STS/SNX17/YWHAH/HSD17B14	5
BP	GO:0009649	entrainment of circadian clock	5/2619	27/18670	0.326	0.5308	0.3981	SIK1/PML/ID2/CRY1/PHLPP1	5
BP	GO:0009651	response to salt stress	5/2619	27/18670	0.326	0.5308	0.3981	AKR1B1/MICU1/ANXA7/LETM1/TH	5
BP	GO:0022616	DNA strand elongation	5/2619	27/18670	0.326	0.5308	0.3981	NBN/POLD2/DNA2/GINS1/RAD50	5
BP	GO:0034067	protein localization to Golgi apparatus	5/2619	27/18670	0.326	0.5308	0.3981	GAK/VPS13C/ARL1/OPTN/GOLPH3	5
BP	GO:0035883	enteroendocrine cell differentiation	5/2619	27/18670	0.326	0.5308	0.3981	BAD/GSK3B/BMP4/INSM1/SMO	5
BP	GO:0048143	astrocyte activation	5/2619	27/18670	0.326	0.5308	0.3981	TREM2/EGFR/IFNG/IL6/SMO	5
BP	GO:0048668	collateral sprouting	5/2619	27/18670	0.326	0.5308	0.3981	SEMA4D/FGF13/EFNA5/RND2/BDNF	5
BP	GO:0051450	myoblast proliferation	5/2619	27/18670	0.326	0.5308	0.3981	HGF/GPX1/IGF1/PAXBP1/ATF2	5
BP	GO:0051953	negative regulation of amine transport	5/2619	27/18670	0.326	0.5308	0.3981	SNCA/HRH3/RGS4/GHSR/ARL6IP5	5
BP	GO:2000144	positive regulation of DNA-templated transcription, initiation	5/2619	27/18670	0.326	0.5308	0.3981	SETX/PSMC2/PSMC3/CREB1/TWIST1	5
BP	GO:2000191	regulation of fatty acid transport	5/2619	27/18670	0.326	0.5308	0.3981	TNFRSF11A/P2RX4/PLA2R1/NCOR1/FABP3	5
BP	GO:0035315	hair cell differentiation	7/2619	40/18670	0.3262	0.5308	0.3981	NOTCH1/MCOLN3/RBPJ/SOD1/JAG2/ERCC2/SLC4A7	7
BP	GO:0046621	negative regulation of organ growth	7/2619	40/18670	0.3262	0.5308	0.3981	JARID2/WWC3/RBP4/RGS4/MAPK11/CTDP1/TBX5	7
BP	GO:0072210	metanephric nephron development	7/2619	40/18670	0.3262	0.5308	0.3981	STAT1/SOX9/BMP4/SIX2/EGR1/PDGFB/SMO	7
BP	GO:0098760	response to interleukin-7	7/2619	40/18670	0.3262	0.5308	0.3981	IL2RG/IL7R/SOCS1/BRWD1/JAK1/STAT5A/CISH	7
BP	GO:0098761	cellular response to interleukin-7	7/2619	40/18670	0.3262	0.5308	0.3981	IL2RG/IL7R/SOCS1/BRWD1/JAK1/STAT5A/CISH	7
BP	GO:0007006	mitochondrial membrane organization	21/2619	134/18670	0.3267	0.5313	0.3985	EYA2/SNCA/NDUFA13/TIMM10/BAD/PINK1/GSK3B/TMEM11/NOL3/GZMB/APOO/TMEM14A/PPP1R13B/TAZ/YWHAH/TP53BP2/ACAA2/HIP1R/ATF2/SAMM50/LETM1	21
BP	GO:0046683	response to organophosphorus	21/2619	134/18670	0.3267	0.5313	0.3985	STAT1/IGFBP5/KCNQ1/NDUFS4/SDC1/BSG/STC1/BIRC2/FDX1/PENK/ITPR2/ASS1/CRHBP/CPS1/P2RX4/SOD1/AKAP9/TYMS/PTK2B/RAP1B/HSPA5	21
BP	GO:0097061	dendritic spine organization	13/2619	80/18670	0.3286	0.5341	0.4006	LGMN/DOCK10/PRNP/BAIAP2/ZNF365/APOE/INSR/SIPA1L1/EPHA4/CTTN/CAPRIN2/CAMK2B/ACTR2	13
BP	GO:1900046	regulation of hemostasis	13/2619	80/18670	0.3286	0.5341	0.4006	VKORC1/PROS1/SERPINE1/APOE/TFPI/F2R/COMP/NOS3/PDGFB/PRKCQ/PRDX2/KRT1/SH2B3	13
BP	GO:0046324	regulation of glucose import	10/2619	60/18670	0.3299	0.536	0.402	ENPP1/PID1/RTN2/INSR/OSBPL8/PEA15/GRB10/PRKCI/IGF1/SORBS1	10
BP	GO:0140053	mitochondrial gene expression	25/2619	162/18670	0.3352	0.5446	0.4084	HSD17B10/MTRF1/UQCC1/MRPL24/MRPL11/RMND1/MRPL40/MRPL23/GFM1/COA3/MRPS33/MRPS28/PRKAA1/MRPS17/PUS1/MRPS22/MRPS11/MRPL17/MRPL20/TFB2M/NGRN/MRPL18/MRPS14/TRMT5/MRPL4	25
BP	GO:0045646	regulation of erythrocyte differentiation	8/2619	47/18670	0.3358	0.5449	0.4087	P4HTM/STAT1/MED1/ZNF16/HIF1A/HOXA5/ID2/TRIM58	8
BP	GO:0048806	genitalia development	8/2619	47/18670	0.3358	0.5449	0.4087	AR/NIPBL/TCF7/RBP4/MERTK/AXL/DHCR24/TYRO3	8
BP	GO:0060351	cartilage development involved in endochondral bone morphogenesis	8/2619	47/18670	0.3358	0.5449	0.4087	HOXA11/SCARA3/SOX9/STC1/COMP/MMP13/COL6A3/MBL2	8
BP	GO:1903115	regulation of actin filament-based movement	8/2619	47/18670	0.3358	0.5449	0.4087	SRI/FGF13/STC1/BIN1/KCNJ2/AKAP9/RANGRF/FLNA	8
BP	GO:0015807	L-amino acid transport	11/2619	67/18670	0.336	0.5449	0.4087	SLC7A5/PRAF2/SLC7A11/SLC7A6/SLC38A1/RGS4/AGT/SLC11A1/ARL6IP5/SFXN1/SLC1A1	11
BP	GO:0030858	positive regulation of epithelial cell differentiation	11/2619	67/18670	0.336	0.5449	0.4087	NOTCH1/SOX9/TMEM100/FOXC1/NCOA3/BAD/SERPINE1/PRKCH/BMP4/MED1/CDH5	11
BP	GO:0000726	non-recombinational repair	15/2619	94/18670	0.3369	0.5451	0.4089	PARP3/SMCHD1/DCLRE1C/ERCC1/NBN/KDM2A/ATM/BARD1/UVRAG/RNF138/SETMAR/RAD50/KAT5/BABAM1/HMGA2	15
BP	GO:0006029	proteoglycan metabolic process	15/2619	94/18670	0.3369	0.5451	0.4089	NDNF/GAL3ST4/UST/EXT2/HEXA/CHST15/EXTL2/IGF1/B4GALT7/SPOCK2/TCF7L2/VCAN/SGSH/CHST12/ARSB	15
BP	GO:0002115	store-operated calcium entry	4/2619	21/18670	0.3392	0.5451	0.4089	HOMER3/ORAI3/MS4A1/STC2	4
BP	GO:0002438	acute inflammatory response to antigenic stimulus	4/2619	21/18670	0.3392	0.5451	0.4089	HLA-E/ELANE/CCR7/CXCR2	4
BP	GO:0003094	glomerular filtration	4/2619	21/18670	0.3392	0.5451	0.4089	CORO2B/F2R/PDGFB/EMP2	4
BP	GO:0006622	protein targeting to lysosome	4/2619	21/18670	0.3392	0.5451	0.4089	CLU/ZFYVE16/GNPTAB/AP4M1	4
BP	GO:0010310	regulation of hydrogen peroxide metabolic process	4/2619	21/18670	0.3392	0.5451	0.4089	SNCA/PINK1/RAC2/PRDX2	4
BP	GO:0014821	phasic smooth muscle contraction	4/2619	21/18670	0.3392	0.5451	0.4089	TACR2/KIT/HTR2B/GHSR	4
BP	GO:0015874	norepinephrine transport	4/2619	21/18670	0.3392	0.5451	0.4089	SNCA/HRH3/AGT/GHSR	4
BP	GO:0016553	base conversion or substitution editing	4/2619	21/18670	0.3392	0.5451	0.4089	ADAR/APOBEC3C/APOBEC3B/ADARB2	4
BP	GO:0030277	maintenance of gastrointestinal epithelium	4/2619	21/18670	0.3392	0.5451	0.4089	SOX9/SERPINA3/RBP4/NOD2	4
BP	GO:0032516	positive regulation of phosphoprotein phosphatase activity	4/2619	21/18670	0.3392	0.5451	0.4089	JAK2/PTPRC/MAGI2/PPP1R12A	4
BP	GO:0032674	regulation of interleukin-5 production	4/2619	21/18670	0.3392	0.5451	0.4089	TNFRSF21/LEF1/IL17RB/IL17RA	4
BP	GO:0032891	negative regulation of organic acid transport	4/2619	21/18670	0.3392	0.5451	0.4089	HRH3/RGS4/PLA2R1/ARL6IP5	4
BP	GO:0035743	CD4-positive, alpha-beta T cell cytokine production	4/2619	21/18670	0.3392	0.5451	0.4089	DENND1B/CD81/IL6/XCL1	4
BP	GO:0035813	regulation of renal sodium excretion	4/2619	21/18670	0.3392	0.5451	0.4089	COMT/AGT/TAC1/CORIN	4
BP	GO:0036120	cellular response to platelet-derived growth factor stimulus	4/2619	21/18670	0.3392	0.5451	0.4089	PTN/CCNA2/HAS2/CREB1	4
BP	GO:0036150	phosphatidylserine acyl-chain remodeling	4/2619	21/18670	0.3392	0.5451	0.4089	PLA2G2D/OSBPL8/PLA1A/LPCAT4	4
BP	GO:0036507	protein demannosylation	4/2619	21/18670	0.3392	0.5451	0.4089	MAN1C1/MAN1B1/EDEM1/SEL1L	4
BP	GO:0036508	protein alpha-1,2-demannosylation	4/2619	21/18670	0.3392	0.5451	0.4089	MAN1C1/MAN1B1/EDEM1/SEL1L	4
BP	GO:0039702	viral budding via host ESCRT complex	4/2619	21/18670	0.3392	0.5451	0.4089	VPS37C/CHMP6/CHMP2A/CHMP1B	4
BP	GO:0042135	neurotransmitter catabolic process	4/2619	21/18670	0.3392	0.5451	0.4089	ALDH7A1/COMT/NAALAD2/HNMT	4
BP	GO:0042402	cellular biogenic amine catabolic process	4/2619	21/18670	0.3392	0.5451	0.4089	ALDH7A1/HAAO/IDO1/HNMT	4
BP	GO:0042403	thyroid hormone metabolic process	4/2619	21/18670	0.3392	0.5451	0.4089	DIO3/MED1/CPQ/DIO2	4
BP	GO:0043153	entrainment of circadian clock by photoperiod	4/2619	21/18670	0.3392	0.5451	0.4089	SIK1/PML/ID2/CRY1	4
BP	GO:0043984	histone H4-K16 acetylation	4/2619	21/18670	0.3392	0.5451	0.4089	MSL3/MSL2/AUTS2/OGT	4
BP	GO:0048026	positive regulation of mRNA splicing, via spliceosome	4/2619	21/18670	0.3392	0.5451	0.4089	CIRBP/PRDX6/DAZAP1/NUP98	4
BP	GO:0051900	regulation of mitochondrial depolarization	4/2619	21/18670	0.3392	0.5451	0.4089	GOT1/TSPO/KDR/MYOC	4
BP	GO:0060044	negative regulation of cardiac muscle cell proliferation	4/2619	21/18670	0.3392	0.5451	0.4089	JARID2/RBP4/MAPK11/TBX5	4
BP	GO:0061003	positive regulation of dendritic spine morphogenesis	4/2619	21/18670	0.3392	0.5451	0.4089	BAIAP2/CAPRIN2/CAMK2B/ACTR2	4
BP	GO:0070920	regulation of production of small RNA involved in gene silencing by RNA	4/2619	21/18670	0.3392	0.5451	0.4089	EGFR/BMP4/PPP3CA/NCOR1	4
BP	GO:0071459	protein localization to chromosome, centromeric region	4/2619	21/18670	0.3392	0.5451	0.4089	NDC80/MIS12/AURKB/CDK1	4
BP	GO:0140058	neuron projection arborization	4/2619	21/18670	0.3392	0.5451	0.4089	PTN/SEMA3A/ZNF365/ROCK1	4
BP	GO:1904886	beta-catenin destruction complex disassembly	4/2619	21/18670	0.3392	0.5451	0.4089	GSK3B/CSNK1A1/FRAT1/FZD2	4
BP	GO:2000269	regulation of fibroblast apoptotic process	4/2619	21/18670	0.3392	0.5451	0.4089	SFRP1/CHD8/STK17B/PIK3CA	4
BP	GO:2000316	regulation of T-helper 17 type immune response	4/2619	21/18670	0.3392	0.5451	0.4089	IL27RA/MALT1/RC3H2/PRKCQ	4
BP	GO:0060359	response to ammonium ion	21/2619	135/18670	0.3397	0.5453	0.409	MAPK3/SNCA/CCNA2/GABRB1/ADA/PENK/PEA15/HRH3/CXCR4/RGS4/CHRNA3/ASS1/CRHBP/SRR/TAC1/ATP2B4/HNMT/PTK2B/HNRNPD/ATF4/HSPA5	21
BP	GO:0007435	salivary gland morphogenesis	6/2619	34/18670	0.3401	0.5453	0.409	HGF/SEMA3A/EGFR/LAMA5/PLXND1/PLXNA1	6
BP	GO:0010574	regulation of vascular endothelial growth factor production	6/2619	34/18670	0.3401	0.5453	0.409	RORA/NDRG2/IL6/HIF1A/CCR2/ATF4	6
BP	GO:0018196	peptidyl-asparagine modification	6/2619	34/18670	0.3401	0.5453	0.409	UBE2J1/DPM3/DAD1/FUT8/DDOST/ASGR1	6
BP	GO:0021522	spinal cord motor neuron differentiation	6/2619	34/18670	0.3401	0.5453	0.409	TCTN1/HOXC10/GDPD5/NFE2L1/ZC4H2/OLIG2	6
BP	GO:0036474	cell death in response to hydrogen peroxide	6/2619	34/18670	0.3401	0.5453	0.409	SIGMAR1/HGF/PINK1/TRAP1/PYCR1/PSAP	6
BP	GO:0045738	negative regulation of DNA repair	6/2619	34/18670	0.3401	0.5453	0.409	SMCHD1/TRIP12/UBQLN4/UBR5/HMGA2/TWIST1	6
BP	GO:0060795	cell fate commitment involved in formation of primary germ layer	6/2619	34/18670	0.3401	0.5453	0.409	HOXA11/EYA2/BMP4/SIX2/ETS2/FZD7	6
BP	GO:1904030	negative regulation of cyclin-dependent protein kinase activity	6/2619	34/18670	0.3401	0.5453	0.409	TNFAIP3/CEBPA/CDKN2C/CDKN1C/KAT2B/CDKN1A	6
BP	GO:0060998	regulation of dendritic spine development	12/2619	74/18670	0.3411	0.5468	0.4101	BAIAP2/ASAP1/APOE/SIPA1L1/PLK2/EPHA4/CAMK1/CDKL5/CAPRIN2/C21orf91/CAMK2B/ACTR2	12
BP	GO:0050871	positive regulation of B cell activation	22/2619	142/18670	0.3418	0.5477	0.4108	CD320/TFRC/TNIP2/PTPRC/CD38/GPR183/BAD/ADA/IGHM/CD28/CD40/CD81/PELI1/TRBC1/CD27/IL6/TNFSF4/NOD2/IGLL5/IGLC1/CDKN1A/XBP1	22
BP	GO:1904950	negative regulation of establishment of protein localization	30/2619	197/18670	0.3427	0.549	0.4118	TNFAIP3/GBP1/SFRP1/CD200/BTN2A2/IL27RA/ANGPT1/SYT11/BARD1/UBE2J1/TNFRSF21/CARD8/APOE/CORO2B/NDFIP1/DNAJA1/PTPN22/RAB11FIP1/PTGER4/F2R/HADH/MAP4K4/GHSR/PML/FERMT1/PPP3CA/RHBDF2/INHBB/TLR8/SRGN	30
BP	GO:0002763	positive regulation of myeloid leukocyte differentiation	9/2619	54/18670	0.3434	0.5494	0.4121	TREM2/CTNNBIP1/LEF1/IFNG/TRIB1/TYROBP/CA2/CREB1/ID2	9
BP	GO:0032210	regulation of telomere maintenance via telomerase	9/2619	54/18670	0.3434	0.5494	0.4121	MAPK3/ATR/TNKS2/ATM/DCP2/HMBOX1/AURKB/HNRNPA1/PRKCQ	9
BP	GO:0035825	homologous recombination	9/2619	54/18670	0.3434	0.5494	0.4121	KLHDC3/UBR2/ATM/RMI1/RAD51C/RAD50/TOP2A/C11orf80/RAD51B	9
BP	GO:0061512	protein localization to cilium	9/2619	54/18670	0.3434	0.5494	0.4121	TCTN1/ARL3/BBS1/BBS4/ZDHHC3/IFT140/SNX10/INPP5E/TCTN2	9
BP	GO:1900047	negative regulation of hemostasis	9/2619	54/18670	0.3434	0.5494	0.4121	PROS1/SERPINE1/APOE/TFPI/COMP/NOS3/PDGFB/KRT1/SH2B3	9
BP	GO:0033238	regulation of cellular amine metabolic process	13/2619	81/18670	0.3455	0.5527	0.4145	SNCA/SLC7A11/PSMB9/COMT/NQO1/PSMC2/PSMB6/PSMC3/PSMD8/PSMB5/PSMD10/ATP2B4/OAZ3	13
BP	GO:1904375	regulation of protein localization to cell periphery	18/2619	115/18670	0.3461	0.5535	0.4152	GBP1/TREM2/AR/PID1/EGFR/PRNP/PRKCH/AP2M1/VTI1B/GPER1/IFNG/PRKCI/TMEM59/GHSR/RANGRF/CIB1/LGALS3/SORBS1	18
BP	GO:1903844	regulation of cellular response to transforming growth factor beta stimulus	19/2619	122/18670	0.3486	0.5565	0.4174	FOLR1/SMAD3/GOT1/CFLAR/MTMR4/ADAM17/TRIM33/HTRA1/ING2/ADAMTSL2/RNF111/ZNF451/CDKN1C/PIN1/UBB/FERMT1/LTBP4/EP300/HSPA5	19
BP	GO:0045921	positive regulation of exocytosis	14/2619	88/18670	0.3493	0.5565	0.4174	SNCA/HLA-F/RAB27A/IL4R/SDC1/FGR/IFNG/CHMP2A/VAMP7/CLASP1/CACNB2/CACNA1D/SYT1/RAB15	14
BP	GO:0050829	defense response to Gram-negative bacterium	14/2619	88/18670	0.3493	0.5565	0.4174	SERPINE1/TNFRSF14/IGHM/ELANE/TUSC2/IL6/SLC11A1/DEFA6/OPTN/GSDMD/IL6R/CTSG/DEFA5/DEFB126	14
BP	GO:0106027	neuron projection organization	14/2619	88/18670	0.3493	0.5565	0.4174	LGMN/DOCK10/PRNP/BAIAP2/ZNF365/APOE/GSK3B/INSR/SIPA1L1/EPHA4/CTTN/CAPRIN2/CAMK2B/ACTR2	14
BP	GO:1901888	regulation of cell junction assembly	14/2619	88/18670	0.3493	0.5565	0.4174	SFRP1/MACF1/SMAD3/PRKCH/LIMCH1/EFNA5/ROCK1/AGT/KDR/MAP4K4/CLASP1/MYOC/VEGFA/RAP1B	14
BP	GO:0001947	heart looping	10/2619	61/18670	0.3495	0.5565	0.4174	NOTCH1/FOLR1/SMAD3/IFT52/C2CD3/BBS4/MICAL2/TMED2/HIF1A/SMO	10
BP	GO:0003170	heart valve development	10/2619	61/18670	0.3495	0.5565	0.4174	NOTCH1/TNFRSF1B/SOX9/BMP4/ROCK1/NOS3/TBX5/RBPJ/PRDM1/TWIST1	10
BP	GO:0032233	positive regulation of actin filament bundle assembly	10/2619	61/18670	0.3495	0.5565	0.4174	SFRP1/SMAD3/PFN2/LIMCH1/WNT11/PPM1E/MYOC/NF2/TAC1/FLNA	10
BP	GO:0006458	'de novo' protein folding	7/2619	41/18670	0.3503	0.5565	0.4174	GAK/HSPH1/DNAJB14/HSPA6/BAG1/HSPA2/HSPA5	7
BP	GO:0007520	myoblast fusion	7/2619	41/18670	0.3503	0.5565	0.4174	CXCL9/CXCL10/PLEKHO1/IL4R/CFLAR/CD81/TNFSF14	7
BP	GO:0019432	triglyceride biosynthetic process	7/2619	41/18670	0.3503	0.5565	0.4174	SIK1/FBXW7/GK/NR1H2/PCK2/LPL/LPIN1	7
BP	GO:0044743	protein transmembrane import into intracellular organelle	7/2619	41/18670	0.3503	0.5565	0.4174	PEX10/NDUFA13/TIMM10/PEX7/PEX2/PEX12/PEX14	7
BP	GO:0050873	brown fat cell differentiation	7/2619	41/18670	0.3503	0.5565	0.4174	CEBPA/SH2B2/FTO/PEX11A/ADRB2/ALDH6A1/CEBPB	7
BP	GO:0061028	establishment of endothelial barrier	7/2619	41/18670	0.3503	0.5565	0.4174	RAP2C/ROCK1/PPP1R16B/CDH5/VEGFA/TJP2/RAP1B	7
BP	GO:1901381	positive regulation of potassium ion transmembrane transport	7/2619	41/18670	0.3503	0.5565	0.4174	ATP1B1/TREM2/KCNQ1/KCNJ2/AKAP9/GAL/FLNA	7
BP	GO:0009799	specification of symmetry	20/2619	129/18670	0.3508	0.5565	0.4174	NOTCH1/FOLR1/GALNT11/SMAD3/AP1B1/IFT52/BMP4/C2CD3/BBS4/MICAL2/FOXF1/NBL1/PSKH1/IFT140/TMED2/HIF1A/SMO/OFD1/DDIT3/DYNC2LI1	20
BP	GO:0034754	cellular hormone metabolic process	20/2619	129/18670	0.3508	0.5565	0.4174	AKR1B1/PNPLA4/AKR1B10/ALDH1A1/DHRS3/DHRS9/RBP4/COMT/HSD17B1/FDX1/CYP11A1/MED1/PLEKHA1/TSPO/EGR1/AKR1C3/ALDH1A3/HSD17B14/SGPL1/AKR1C4	20
BP	GO:0045814	negative regulation of gene expression, epigenetic	21/2619	136/18670	0.3528	0.5565	0.4174	MTF2/JARID2/SMCHD1/SUZ12/DNMT1/UBR2/EZH2/ATF7IP/ATAD2B/MSL3/FAM172A/ARID1A/PCGF1/EED/HMGB1/SMARCA5/HDAC1/ATAD2/BAZ2A/HMGA1/MORF4L1	21
BP	GO:0000098	sulfur amino acid catabolic process	3/2619	15/18670	0.3532	0.5565	0.4174	CBS/MPST/TXN2	3
BP	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	3/2619	15/18670	0.3532	0.5565	0.4174	DDX1/CSTF2/RTCB	3
BP	GO:0015671	oxygen transport	3/2619	15/18670	0.3532	0.5565	0.4174	MYC/IPCEF1/HBB	3
BP	GO:0019321	pentose metabolic process	3/2619	15/18670	0.3532	0.5565	0.4174	FGGY/RBKS/RPE	3
BP	GO:0030238	male sex determination	3/2619	15/18670	0.3532	0.5565	0.4174	AR/SOX9/INSR	3
BP	GO:0030812	negative regulation of nucleotide catabolic process	3/2619	15/18670	0.3532	0.5565	0.4174	NUPR1/CBFA2T3/DDIT4	3
BP	GO:0031054	pre-miRNA processing	3/2619	15/18670	0.3532	0.5565	0.4174	ADAR/PRKRA/AGO3	3
BP	GO:0031573	intra-S DNA damage checkpoint	3/2619	15/18670	0.3532	0.5565	0.4174	CHEK2/RAD9A/ATF2	3
BP	GO:0032105	negative regulation of response to extracellular stimulus	3/2619	15/18670	0.3532	0.5565	0.4174	BBS4/GHSR/KANK2	3
BP	GO:0032108	negative regulation of response to nutrient levels	3/2619	15/18670	0.3532	0.5565	0.4174	BBS4/GHSR/KANK2	3
BP	GO:0032274	gonadotropin secretion	3/2619	15/18670	0.3532	0.5565	0.4174	TACR2/TMF1/INHBB	3
BP	GO:0032352	positive regulation of hormone metabolic process	3/2619	15/18670	0.3532	0.5565	0.4174	IFNG/EGR1/HIF1A	3
BP	GO:0033008	positive regulation of mast cell activation involved in immune response	3/2619	15/18670	0.3532	0.5565	0.4174	IL4R/FGR/VAMP7	3
BP	GO:0035635	entry of bacterium into host cell	3/2619	15/18670	0.3532	0.5565	0.4174	EXOC7/EXOC2/CXCL8	3
BP	GO:0042559	pteridine-containing compound biosynthetic process	3/2619	15/18670	0.3532	0.5565	0.4174	GCH1/QDPR/PCBD1	3
BP	GO:0043306	positive regulation of mast cell degranulation	3/2619	15/18670	0.3532	0.5565	0.4174	IL4R/FGR/VAMP7	3
BP	GO:0043508	negative regulation of JUN kinase activity	3/2619	15/18670	0.3532	0.5565	0.4174	SFRP1/DNAJA1/PTPN22	3
BP	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	3/2619	15/18670	0.3532	0.5565	0.4174	ATR/ATM/PLA2R1	3
BP	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	3/2619	15/18670	0.3532	0.5565	0.4174	CD44/PSMD10/TWIST1	3
BP	GO:0043584	nose development	3/2619	15/18670	0.3532	0.5565	0.4174	SIX1/SMCHD1/ALDH1A3	3
BP	GO:0045838	positive regulation of membrane potential	3/2619	15/18670	0.3532	0.5565	0.4174	BAD/ANK3/STOML2	3
BP	GO:0050651	dermatan sulfate proteoglycan biosynthetic process	3/2619	15/18670	0.3532	0.5565	0.4174	UST/VCAN/CHST12	3
BP	GO:0050961	detection of temperature stimulus involved in sensory perception	3/2619	15/18670	0.3532	0.5565	0.4174	CXCR4/NTRK1/ANO1	3
BP	GO:0050965	detection of temperature stimulus involved in sensory perception of pain	3/2619	15/18670	0.3532	0.5565	0.4174	CXCR4/NTRK1/ANO1	3
BP	GO:0051044	positive regulation of membrane protein ectodomain proteolysis	3/2619	15/18670	0.3532	0.5565	0.4174	TNFRSF1B/APOE/IFNG	3
BP	GO:0051198	negative regulation of coenzyme metabolic process	3/2619	15/18670	0.3532	0.5565	0.4174	NUPR1/CBFA2T3/DDIT4	3
BP	GO:0060841	venous blood vessel development	3/2619	15/18670	0.3532	0.5565	0.4174	NOTCH1/FOXF1/VEGFA	3
BP	GO:0070365	hepatocyte differentiation	3/2619	15/18670	0.3532	0.5565	0.4174	TAF10/CPS1/PCK2	3
BP	GO:0071599	otic vesicle development	3/2619	15/18670	0.3532	0.5565	0.4174	SIX1/SOX9/CEP290	3
BP	GO:0071801	regulation of podosome assembly	3/2619	15/18670	0.3532	0.5565	0.4174	LCP1/ASAP1/ARHGEF2	3
BP	GO:0072075	metanephric mesenchyme development	3/2619	15/18670	0.3532	0.5565	0.4174	SIX1/STAT1/MYC	3
BP	GO:0072148	epithelial cell fate commitment	3/2619	15/18670	0.3532	0.5565	0.4174	NOTCH1/RBPJ/JAG2	3
BP	GO:0090136	epithelial cell-cell adhesion	3/2619	15/18670	0.3532	0.5565	0.4174	THBS4/KIT/ITGB5	3
BP	GO:0090141	positive regulation of mitochondrial fission	3/2619	15/18670	0.3532	0.5565	0.4174	FIS1/PINK1/KDR	3
BP	GO:0090197	positive regulation of chemokine secretion	3/2619	15/18670	0.3532	0.5565	0.4174	IL4R/POSTN/LPL	3
BP	GO:0098840	protein transport along microtubule	3/2619	15/18670	0.3532	0.5565	0.4174	HSPB1/KIF5C/SFPQ	3
BP	GO:0099118	microtubule-based protein transport	3/2619	15/18670	0.3532	0.5565	0.4174	HSPB1/KIF5C/SFPQ	3
BP	GO:1902188	positive regulation of viral release from host cell	3/2619	15/18670	0.3532	0.5565	0.4174	PC/CHMP2A/VAPA	3
BP	GO:1902969	mitotic DNA replication	3/2619	15/18670	0.3532	0.5565	0.4174	CHEK2/GINS1/BRCA2	3
BP	GO:1903543	positive regulation of exosomal secretion	3/2619	15/18670	0.3532	0.5565	0.4174	SDC1/IFNG/CHMP2A	3
BP	GO:2000402	negative regulation of lymphocyte migration	3/2619	15/18670	0.3532	0.5565	0.4174	CD200/IL27RA/PADI2	3
BP	GO:0046323	glucose import	11/2619	68/18670	0.3546	0.5585	0.4189	ENPP1/PID1/RTN2/INSR/OSBPL8/PEA15/GRB10/PRKCI/IGF1/SORT1/SORBS1	11
BP	GO:0002691	regulation of cellular extravasation	5/2619	28/18670	0.3555	0.5585	0.4189	IL27RA/PLVAP/PTGER4/ELANE/CCR2	5
BP	GO:0006972	hyperosmotic response	5/2619	28/18670	0.3555	0.5585	0.4189	AKR1B1/ARHGEF2/MICU1/HNMT/LETM1	5
BP	GO:0008209	androgen metabolic process	5/2619	28/18670	0.3555	0.5585	0.4189	DHRS9/MED1/PLEKHA1/SGPL1/AKR1C4	5
BP	GO:0021846	cell proliferation in forebrain	5/2619	28/18670	0.3555	0.5585	0.4189	PCM1/DCT/SIX3/FABP7/EMX2	5
BP	GO:0031440	regulation of mRNA 3'-end processing	5/2619	28/18670	0.3555	0.5585	0.4189	BARD1/CPSF7/CCNB1/NCBP2/CDK9	5
BP	GO:0045761	regulation of adenylate cyclase activity	5/2619	28/18670	0.3555	0.5585	0.4189	TIMP2/AKAP9/CACNA1D/GALR3/CCR2	5
BP	GO:0070076	histone lysine demethylation	5/2619	28/18670	0.3555	0.5585	0.4189	JARID2/KDM5A/KDM2A/KDM3A/KDM7A	5
BP	GO:0070198	protein localization to chromosome, telomeric region	5/2619	28/18670	0.3555	0.5585	0.4189	ATR/TNKS2/BRCA2/ATRX/NABP2	5
BP	GO:0070861	regulation of protein exit from endoplasmic reticulum	5/2619	28/18670	0.3555	0.5585	0.4189	UBE2J1/TMEM30A/CD81/SEC16A/EDEM1	5
BP	GO:0090383	phagosome acidification	5/2619	28/18670	0.3555	0.5585	0.4189	SLAMF8/ATP6V0D1/TCIRG1/ATP6V0E2/RAB20	5
BP	GO:1902932	positive regulation of alcohol biosynthetic process	5/2619	28/18670	0.3555	0.5585	0.4189	SNCA/PTH1R/GPER1/IFNG/PRKAA1	5
BP	GO:0035567	non-canonical Wnt signaling pathway	23/2619	150/18670	0.3562	0.5594	0.4196	SFRP1/PSMB9/AP2M1/WNT11/PLEKHA4/MAGI2/LEF1/PSMC2/FZD3/PSMB6/PSMC3/MYOC/PSMD8/PSMB5/CSNK1E/NLK/PPP3CA/PSMD10/AGO3/TCF7L2/FZD6/FZD7/FZD2	23
BP	GO:0007140	male meiotic nuclear division	8/2619	48/18670	0.3581	0.5616	0.4212	MYBL1/UBR2/ATM/ING2/BRCA2/UBB/RAD51C/HSPA2	8
BP	GO:0007528	neuromuscular junction development	8/2619	48/18670	0.3581	0.5616	0.4212	SIX1/PTN/ERBB2/ANK3/F2R/CACNB2/ZC4H2/COL4A1	8
BP	GO:0007595	lactation	8/2619	48/18670	0.3581	0.5616	0.4212	MED1/VEGFA/HIF1A/CREB1/STAT5A/OAS2/ERBB4/XBP1	8
BP	GO:0008038	neuron recognition	8/2619	48/18670	0.3581	0.5616	0.4212	SEMA3A/TNFRSF21/NDN/BSG/CXCR4/EPHA4/ARHGAP35/DSCAM	8
BP	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	8/2619	48/18670	0.3581	0.5616	0.4212	PCDHB13/CDH2/PCDHB6/PCDHB3/ATP2C1/PCDHB11/CDH5/CDH12	8
BP	GO:2000059	negative regulation of ubiquitin-dependent protein catabolic process	8/2619	48/18670	0.3581	0.5616	0.4212	HFE/FHIT/PML/OGT/RYBP/N4BP1/CLEC16A/USP14	8
BP	GO:0010833	telomere maintenance via telomere lengthening	13/2619	82/18670	0.3626	0.5684	0.4263	MAPK3/HNRNPA2B1/ATR/TNKS2/ATM/NHP2/RPA1/DCP2/HMBOX1/AURKB/HNRNPA1/PRKCQ/RAD50	13
BP	GO:0003229	ventricular cardiac muscle tissue development	9/2619	55/18670	0.3643	0.5706	0.428	NOTCH1/FOXC1/RXRA/MED1/MYL3/ZFPM2/TBX5/RBPJ/ID2	9
BP	GO:0043113	receptor clustering	9/2619	55/18670	0.3643	0.5706	0.428	PTN/CDH2/SLC7A11/ITGAL/APOE/MAGI2/ITGB7/CD81/FLNA	9
BP	GO:0044273	sulfur compound catabolic process	9/2619	55/18670	0.3643	0.5706	0.428	CBS/HEXA/ACAT1/MPST/AHCY/TXN2/VCAN/KERA/ARSB	9
BP	GO:0098900	regulation of action potential	9/2619	55/18670	0.3643	0.5706	0.428	FGF13/BIN1/KCNJ2/ANK3/AKAP9/RANGRF/TAC1/CXADR/FLNA	9
BP	GO:0031644	regulation of neurological system process	21/2619	137/18670	0.366	0.573	0.4298	TNFRSF1B/SH3GL1/TMEM100/HGF/ITGAX/TNFRSF21/COMT/BAIAP2/TYMP/F2R/ADRB2/RGS4/AGT/KLK8/NOS3/HCRT/GHSR/CST7/AKAP9/PTK2B/TENM4	21
BP	GO:0003203	endocardial cushion morphogenesis	6/2619	35/18670	0.3666	0.5731	0.4299	NOTCH1/SOX9/TMEM100/NOS3/RBPJ/TWIST1	6
BP	GO:0021955	central nervous system neuron axonogenesis	6/2619	35/18670	0.3666	0.5731	0.4299	SCN1B/TCTN1/MYCBP2/EPHA4/ARHGAP35/TSKU	6
BP	GO:0032689	negative regulation of interferon-gamma production	6/2619	35/18670	0.3666	0.5731	0.4299	PRNP/CD96/AXL/XCL1/TNFSF4/HMGB1	6
BP	GO:0048333	mesodermal cell differentiation	6/2619	35/18670	0.3666	0.5731	0.4299	HOXA11/EYA2/BMP4/FOXF1/SIX2/HMGA2	6
BP	GO:0060338	regulation of type I interferon-mediated signaling pathway	6/2619	35/18670	0.3666	0.5731	0.4299	ADAR/TBK1/SAMHD1/IRF3/PTPN2/MMP12	6
BP	GO:0071108	protein K48-linked deubiquitination	6/2619	35/18670	0.3666	0.5731	0.4299	TNFAIP3/USP34/USP27X/USP8/USP9X/CYLD	6
BP	GO:0010830	regulation of myotube differentiation	10/2619	62/18670	0.3693	0.5771	0.4328	CXCL9/SIK1/CXCL10/NOTCH1/IL4R/CFLAR/MAML1/TNFSF14/XBP1/BDNF	10
BP	GO:1904356	regulation of telomere maintenance via telomere lengthening	10/2619	62/18670	0.3693	0.5771	0.4328	MAPK3/HNRNPA2B1/ATR/TNKS2/ATM/DCP2/HMBOX1/AURKB/HNRNPA1/PRKCQ	10
BP	GO:0006836	neurotransmitter transport	40/2619	269/18670	0.3705	0.5788	0.4341	SLC18A2/TACR2/SNCA/PRAF2/RIMS3/PREPL/PRKCB/SYT11/SLC29A1/SLC7A11/SYNJ1/PFN2/MCTP1/ADA/GSK3B/HRH3/GPER1/SLC38A1/SYT17/LIN7B/RGS4/CHRNA3/PTPRN2/SNCAIP/HCRT/VAMP7/ADCY1/SV2B/ARL6IP5/VAMP2/CACNB2/HBB/CACNA1D/SEC14L1/SYT1/SYN1/RAP1B/NAPA/SLC1A1/TH	40
BP	GO:0016101	diterpenoid metabolic process	17/2619	110/18670	0.3729	0.5801	0.4351	AKR1B1/PNPLA4/AKR1B10/GPC5/APOM/ALDH1A1/DHRS3/DHRS9/SDC1/RBP4/EGFR/APOE/AKR1C3/ALDH3A2/ALDH1A3/LPL/AKR1C4	17
BP	GO:1903034	regulation of response to wounding	27/2619	179/18670	0.3731	0.5801	0.4351	TNFAIP3/VKORC1/PTN/PROS1/SMAD3/PTPRF/SERPINE1/APOE/TFPI/CXCR4/F2R/CERS2/KLK8/NOS3/HBEGF/CLASP1/PDGFB/EPHA4/PRKCQ/PRDX2/KRT1/CDKN1A/XBP1/SH2B3/ARFGEF1/REG3A/LRIG2	27
BP	GO:0016226	iron-sulfur cluster assembly	4/2619	22/18670	0.3731	0.5801	0.4351	MMS19/NUBPL/NUBP2/NFU1	4
BP	GO:0023058	adaptation of signaling pathway	4/2619	22/18670	0.3731	0.5801	0.4351	HTR2B/ARRB1/ADRB2/RS1	4
BP	GO:0031163	metallo-sulfur cluster assembly	4/2619	22/18670	0.3731	0.5801	0.4351	MMS19/NUBPL/NUBP2/NFU1	4
BP	GO:0032069	regulation of nuclease activity	4/2619	22/18670	0.3731	0.5801	0.4351	DDX11/GZMA/HMGB1/OAS2	4
BP	GO:0032469	endoplasmic reticulum calcium ion homeostasis	4/2619	22/18670	0.3731	0.5801	0.4351	FIS1/HERPUD1/TMCO1/PML	4
BP	GO:0032634	interleukin-5 production	4/2619	22/18670	0.3731	0.5801	0.4351	TNFRSF21/LEF1/IL17RB/IL17RA	4
BP	GO:0032928	regulation of superoxide anion generation	4/2619	22/18670	0.3731	0.5801	0.4351	EGFR/AGT/TYROBP/SOD1	4
BP	GO:0036119	response to platelet-derived growth factor	4/2619	22/18670	0.3731	0.5801	0.4351	PTN/CCNA2/HAS2/CREB1	4
BP	GO:0042359	vitamin D metabolic process	4/2619	22/18670	0.3731	0.5801	0.4351	LGMN/CYP11A1/NFKB1/IFNG	4
BP	GO:0045624	positive regulation of T-helper cell differentiation	4/2619	22/18670	0.3731	0.5801	0.4351	RIPK2/MALT1/IL4R/TNFSF4	4
BP	GO:0046339	diacylglycerol metabolic process	4/2619	22/18670	0.3731	0.5801	0.4351	DGKA/DGKZ/ANG/PLCE1	4
BP	GO:0071359	cellular response to dsRNA	4/2619	22/18670	0.3731	0.5801	0.4351	COLEC12/IRF3/NFKB1/RIOK3	4
BP	GO:0071404	cellular response to low-density lipoprotein particle stimulus	4/2619	22/18670	0.3731	0.5801	0.4351	PPARG/CD81/LPL/NPC1	4
BP	GO:0097205	renal filtration	4/2619	22/18670	0.3731	0.5801	0.4351	CORO2B/F2R/PDGFB/EMP2	4
BP	GO:0140112	extracellular vesicle biogenesis	4/2619	22/18670	0.3731	0.5801	0.4351	RAB27A/SDC1/IFNG/CHMP2A	4
BP	GO:1901798	positive regulation of signal transduction by p53 class mediator	4/2619	22/18670	0.3731	0.5801	0.4351	ATR/ATM/PLA2R1/UBB	4
BP	GO:1903077	negative regulation of protein localization to plasma membrane	4/2619	22/18670	0.3731	0.5801	0.4351	GBP1/PID1/AP2M1/TMEM59	4
BP	GO:2001032	regulation of double-strand break repair via nonhomologous end joining	4/2619	22/18670	0.3731	0.5801	0.4351	PARP3/SMCHD1/SETMAR/HMGA2	4
BP	GO:2000243	positive regulation of reproductive process	11/2619	69/18670	0.3734	0.5803	0.4353	CDC25B/AR/SOX9/SEMA3A/INSR/ZFPM2/YTHDC2/CIB1/PIWIL2/INHBB/DAZL	11
BP	GO:0030308	negative regulation of cell growth	28/2619	186/18670	0.374	0.5811	0.4358	SFRP1/ENPP1/SEMA4D/SMAD3/SEMA4A/NDUFA13/SEMA3A/FGF13/CDKN2C/SEMA4C/WNT11/PPARG/PHB/CRYAB/RGS4/AGT/SEMA3F/CTDP1/CRLF3/PML/SEMA3E/GDF9/TNK1/NDUFS3/GAL/CDKN1A/CAPRIN2/BCL11A	28
BP	GO:0032958	inositol phosphate biosynthetic process	7/2619	42/18670	0.3746	0.5819	0.4364	PLCG2/SNCA/PTH1R/GPER1/PLCE1/PLCD1/PTK2B	7
BP	GO:0007492	endoderm development	12/2619	76/18670	0.3768	0.5848	0.4386	NOTCH1/SMAD3/ITGA5/BMP4/HSBP1/HDAC1/SETD2/BPTF/ITGB5/HOXC11/COL4A2/HMGA2	12
BP	GO:0019674	NAD metabolic process	12/2619	76/18670	0.3768	0.5848	0.4386	HAAO/CD38/IDO1/ENO2/PFKM/MDH2/NAMPT/NADSYN1/ALDOC/NT5E/MDH1/ADPGK	12
BP	GO:0046902	regulation of mitochondrial membrane permeability	12/2619	76/18670	0.3768	0.5848	0.4386	EYA2/BAD/GSK3B/NOL3/GZMB/TMEM14A/PPP1R13B/YWHAH/TP53BP2/ACAA2/HIP1R/ATF2	12
BP	GO:0060411	cardiac septum morphogenesis	12/2619	76/18670	0.3768	0.5848	0.4386	NOTCH1/DHRS3/BMP4/WNT11/RBM15/ZFPM2/NOS3/TBX5/RBPJ/ID2/SMO/FZD2	12
BP	GO:1902807	negative regulation of cell cycle G1/S phase transition	20/2619	131/18670	0.3779	0.5864	0.4398	BTN2A2/RFWD3/CRADD/CHEK2/EZH2/ATM/CDKN2C/CDK4/CTDSPL/MYO16/PLK2/CCNB1/PML/GTSE1/CDK1/CDKN1A/WEE1/EP300/KANK2/RBL2	20
BP	GO:0098659	inorganic cation import across plasma membrane	13/2619	83/18670	0.3797	0.5889	0.4417	ATP1B1/SLC12A8/PRNP/SLC12A7/HFE/KCNJ2/IFNG/SLC39A8/FAM155A/CALCR/SLC39A14/KCNJ8/ATP2B4	13
BP	GO:0099587	inorganic ion import across plasma membrane	13/2619	83/18670	0.3797	0.5889	0.4417	ATP1B1/SLC12A8/PRNP/SLC12A7/HFE/KCNJ2/IFNG/SLC39A8/FAM155A/CALCR/SLC39A14/KCNJ8/ATP2B4	13
BP	GO:0002534	cytokine production involved in inflammatory response	8/2619	49/18670	0.3806	0.5893	0.442	IDO1/CD96/C5orf30/CUEDC2/NOD2/IL17RC/MYD88/IL17RA	8
BP	GO:0002686	negative regulation of leukocyte migration	8/2619	49/18670	0.3806	0.5893	0.442	SLAMF8/CD200/IL27RA/ADA/PTGER4/NBL1/PADI2/HOXA7	8
BP	GO:0003254	regulation of membrane depolarization	8/2619	49/18670	0.3806	0.5893	0.442	SCN1B/GOT1/ANK3/TSPO/KDR/MYOC/RANGRF/NEDD4L	8
BP	GO:0010712	regulation of collagen metabolic process	8/2619	49/18670	0.3806	0.5893	0.442	MFAP4/GOT1/BMP4/PPARG/F2R/IL6/SUCO/LARP6	8
BP	GO:0071715	icosanoid transport	8/2619	49/18670	0.3806	0.5893	0.442	PLA2G2D/ABCC4/TNFRSF11A/SLCO3A1/ABCC1/P2RX4/PLA2R1/NMB	8
BP	GO:0071825	protein-lipid complex subunit organization	8/2619	49/18670	0.3806	0.5893	0.442	LIPC/APOM/APOE/BIN1/PLA2G7/APOC1/AGT/LPL	8
BP	GO:1901571	fatty acid derivative transport	8/2619	49/18670	0.3806	0.5893	0.442	PLA2G2D/ABCC4/TNFRSF11A/SLCO3A1/ABCC1/P2RX4/PLA2R1/NMB	8
BP	GO:0048489	synaptic vesicle transport	23/2619	152/18670	0.3815	0.5903	0.4427	SNCA/RIMS3/PREPL/PRKCB/SYT11/RAB27A/SPG11/SYNJ1/PFN2/PINK1/GSK3B/BLOC1S1/TMEM230/SYT17/KIF5C/ADCY1/VAMP2/CACNB2/CACNA1D/SYT1/SYN1/RAP1B/NAPA	23
BP	GO:0097480	establishment of synaptic vesicle localization	23/2619	152/18670	0.3815	0.5903	0.4427	SNCA/RIMS3/PREPL/PRKCB/SYT11/RAB27A/SPG11/SYNJ1/PFN2/PINK1/GSK3B/BLOC1S1/TMEM230/SYT17/KIF5C/ADCY1/VAMP2/CACNB2/CACNA1D/SYT1/SYN1/RAP1B/NAPA	23
BP	GO:0009953	dorsal/ventral pattern formation	14/2619	90/18670	0.3822	0.5913	0.4435	HOXA11/SFRP1/TCTN1/IFT52/MDFI/BMP4/FKBP8/EVX1/NBL1/EN1/CXXC4/SIX3/SMO/DDIT3	14
BP	GO:0010390	histone monoubiquitination	5/2619	29/18670	0.3851	0.5939	0.4454	SKP1/PCGF1/DDB2/RYBP/RING1	5
BP	GO:0010669	epithelial structure maintenance	5/2619	29/18670	0.3851	0.5939	0.4454	SOX9/SERPINA3/RBP4/NOD2/CXADR	5
BP	GO:0014044	Schwann cell development	5/2619	29/18670	0.3851	0.5939	0.4454	NTRK2/ADAM22/MYOC/SOD1/FA2H	5
BP	GO:0035025	positive regulation of Rho protein signal transduction	5/2619	29/18670	0.3851	0.5939	0.4454	ARRB1/F2R/AKAP13/COL3A1/GPR4	5
BP	GO:0042226	interleukin-6 biosynthetic process	5/2619	29/18670	0.3851	0.5939	0.4454	GHSR/EREG/TYROBP/BCL10/CEBPB	5
BP	GO:0044550	secondary metabolite biosynthetic process	5/2619	29/18670	0.3851	0.5939	0.4454	CBS/SLC7A11/BDH2/MPST/DCT	5
BP	GO:0051642	centrosome localization	5/2619	29/18670	0.3851	0.5939	0.4454	NDE1/ASPM/SYNE2/RANBP2/AKAP9	5
BP	GO:0060441	epithelial tube branching involved in lung morphogenesis	5/2619	29/18670	0.3851	0.5939	0.4454	SOX9/BMP4/FOXF1/HOXA5/KRAS	5
BP	GO:0060536	cartilage morphogenesis	5/2619	29/18670	0.3851	0.5939	0.4454	SCARA3/STC1/COL6A3/MBL2/HOXA5	5
BP	GO:0071280	cellular response to copper ion	5/2619	29/18670	0.3851	0.5939	0.4454	SNCA/PRNP/DAXX/NFE2L1/AQP2	5
BP	GO:0072606	interleukin-8 secretion	5/2619	29/18670	0.3851	0.5939	0.4454	PTPN22/F2R/CD58/CD2/FCN1	5
BP	GO:0090162	establishment of epithelial cell polarity	5/2619	29/18670	0.3851	0.5939	0.4454	FOXF1/CLASP1/SIPA1L3/FERMT1/GOLPH3	5
BP	GO:2000036	regulation of stem cell population maintenance	5/2619	29/18670	0.3851	0.5939	0.4454	PTN/NCOA3/KDM3A/SMO/HMGA2	5
BP	GO:0034508	centromere complex assembly	9/2619	56/18670	0.3854	0.5941	0.4456	CENPE/NASP/MIS12/HJURP/CENPT/SMARCA5/CENPC/CENPF/POGZ	9
BP	GO:0006415	translational termination	16/2619	104/18670	0.3862	0.595	0.4463	MTRF1/MRPL24/TRMT112/MRPL11/MRPL40/MRPL23/MRPS33/MRPS28/MRPS17/MRPS22/MRPS11/MRPL17/MRPL20/MRPL18/MRPS14/MRPL4	16
BP	GO:0019233	sensory perception of pain	16/2619	104/18670	0.3862	0.595	0.4463	MAPK3/TMEM100/UCHL1/NDN/COMT/PENK/CXCR4/F2R/NIPSNAP1/NTRK1/NPY1R/P2RX4/ANO1/SCN9A/TAC1/CCR2	16
BP	GO:0032414	positive regulation of ion transmembrane transporter activity	16/2619	104/18670	0.3862	0.595	0.4463	ATP1B1/TREM2/PLCG2/FGF14/PINK1/EHD3/ANK3/ADRB2/IFNG/S100A1/CACNB2/ABCB1/AKAP9/GAL/HSPA2/CCR2	16
BP	GO:0031646	positive regulation of neurological system process	10/2619	63/18670	0.3892	0.599	0.4493	TNFRSF1B/HGF/ITGAX/BAIAP2/ADRB2/RGS4/HCRT/CST7/PTK2B/TENM4	10
BP	GO:0032371	regulation of sterol transport	10/2619	63/18670	0.3892	0.599	0.4493	NFKBIA/EGF/APOE/PPARG/NFKB1/APOC1/TSPO/NR1H2/SCP2/ABCA2	10
BP	GO:0032374	regulation of cholesterol transport	10/2619	63/18670	0.3892	0.599	0.4493	NFKBIA/EGF/APOE/PPARG/NFKB1/APOC1/TSPO/NR1H2/SCP2/ABCA2	10
BP	GO:0031929	TOR signaling	19/2619	125/18670	0.3905	0.599	0.4493	SIK1/TREM2/UBR2/DDIT4/ATM/DEPTOR/PINK1/RRAGA/SEC13/PRR5L/LAMTOR2/MLST8/HIF1A/PRKAA1/RRAGD/GOLPH3/SESN1/CLEC16A/PIK3CA	19
BP	GO:0070988	demethylation	11/2619	70/18670	0.3923	0.599	0.4493	JARID2/KDM5A/KDM2A/FTO/TDG/APOBEC3C/KDM3A/KDM7A/JMJD6/APOBEC3B/USP9X	11
BP	GO:0000154	rRNA modification	6/2619	36/18670	0.3932	0.599	0.4493	NHP2/TRMT112/DIMT1/TFB2M/TSR3/THUMPD1	6
BP	GO:0003091	renal water homeostasis	6/2619	36/18670	0.3932	0.599	0.4493	AKR1B1/PRKAR2A/ADCY1/AQP2/HAS2/ADCY2	6
BP	GO:0003417	growth plate cartilage development	6/2619	36/18670	0.3932	0.599	0.4493	SCARA3/STC1/COMP/MMP13/COL6A3/MBL2	6
BP	GO:0006007	glucose catabolic process	6/2619	36/18670	0.3932	0.599	0.4493	BAD/ENO2/PFKM/LRP5/ALDOC/ADPGK	6
BP	GO:0090313	regulation of protein targeting to membrane	6/2619	36/18670	0.3932	0.599	0.4493	FIS1/PRNP/ERBB2/ANK3/VAMP7/CIB1	6
BP	GO:0090322	regulation of superoxide metabolic process	6/2619	36/18670	0.3932	0.599	0.4493	GCH1/FBLN5/EGFR/AGT/TYROBP/SOD1	6
BP	GO:2000310	regulation of NMDA receptor activity	6/2619	36/18670	0.3932	0.599	0.4493	PINK1/GRIA2/IFNG/CRHBP/PTK2B/CCR2	6
BP	GO:0000394	RNA splicing, via endonucleolytic cleavage and ligation	3/2619	16/18670	0.3939	0.599	0.4493	DDX1/CSTF2/RTCB	3
BP	GO:0002295	T-helper cell lineage commitment	3/2619	16/18670	0.3939	0.599	0.4493	LY9/IL6/BATF	3
BP	GO:0003222	ventricular trabecula myocardium morphogenesis	3/2619	16/18670	0.3939	0.599	0.4493	NOTCH1/MED1/RBPJ	3
BP	GO:0006103	2-oxoglutarate metabolic process	3/2619	16/18670	0.3939	0.599	0.4493	GOT1/PHYH/DLD	3
BP	GO:0006837	serotonin transport	3/2619	16/18670	0.3939	0.599	0.4493	SLC18A2/SNCA/HRH3	3
BP	GO:0010875	positive regulation of cholesterol efflux	3/2619	16/18670	0.3939	0.599	0.4493	NFKBIA/APOE/NR1H2	3
BP	GO:0010885	regulation of cholesterol storage	3/2619	16/18670	0.3939	0.599	0.4493	PPARG/NR1H2/LPL	3
BP	GO:0010934	macrophage cytokine production	3/2619	16/18670	0.3939	0.599	0.4493	IRAK3/HLA-G/CUEDC2	3
BP	GO:0014061	regulation of norepinephrine secretion	3/2619	16/18670	0.3939	0.599	0.4493	HRH3/AGT/GHSR	3
BP	GO:0016114	terpenoid biosynthetic process	3/2619	16/18670	0.3939	0.599	0.4493	DHRS9/AKR1C3/ALDH1A3	3
BP	GO:0021542	dentate gyrus development	3/2619	16/18670	0.3939	0.599	0.4493	LEF1/SMO/EMX2	3
BP	GO:0030952	establishment or maintenance of cytoskeleton polarity	3/2619	16/18670	0.3939	0.599	0.4493	RHOF/RND2/ARHGAP35	3
BP	GO:0031269	pseudopodium assembly	3/2619	16/18670	0.3939	0.599	0.4493	CDC42EP3/KIT/CCR7	3
BP	GO:0032305	positive regulation of icosanoid secretion	3/2619	16/18670	0.3939	0.599	0.4493	TNFRSF11A/P2RX4/PLA2R1	3
BP	GO:0035970	peptidyl-threonine dephosphorylation	3/2619	16/18670	0.3939	0.599	0.4493	DUSP5/PPM1E/PPM1B	3
BP	GO:0043031	negative regulation of macrophage activation	3/2619	16/18670	0.3939	0.599	0.4493	CD200/PTPRC/CST7	3
BP	GO:0043174	nucleoside salvage	3/2619	16/18670	0.3939	0.599	0.4493	TK2/ADK/TYMP	3
BP	GO:0043252	sodium-independent organic anion transport	3/2619	16/18670	0.3939	0.599	0.4493	SLC16A2/SLCO4A1/SLCO3A1	3
BP	GO:0044849	estrous cycle	3/2619	16/18670	0.3939	0.599	0.4493	PTN/EGR1/HAS2	3
BP	GO:0045116	protein neddylation	3/2619	16/18670	0.3939	0.599	0.4493	UBE2M/NEDD8/DCUN1D1	3
BP	GO:0045623	negative regulation of T-helper cell differentiation	3/2619	16/18670	0.3939	0.599	0.4493	IL4R/RC3H2/TNFSF4	3
BP	GO:0050655	dermatan sulfate proteoglycan metabolic process	3/2619	16/18670	0.3939	0.599	0.4493	UST/VCAN/CHST12	3
BP	GO:0050711	negative regulation of interleukin-1 secretion	3/2619	16/18670	0.3939	0.599	0.4493	TNFAIP3/CARD8/PML	3
BP	GO:0050774	negative regulation of dendrite morphogenesis	3/2619	16/18670	0.3939	0.599	0.4493	YWHAH/TLX2/PPP3CA	3
BP	GO:0051447	negative regulation of meiotic cell cycle	3/2619	16/18670	0.3939	0.599	0.4493	NPR2/RAD1/FBXO5	3
BP	GO:0051571	positive regulation of histone H3-K4 methylation	3/2619	16/18670	0.3939	0.599	0.4493	WDR61/DNMT1/AUTS2	3
BP	GO:0051923	sulfation	3/2619	16/18670	0.3939	0.599	0.4493	UST/TPST1/SULT1A2	3
BP	GO:0055119	relaxation of cardiac muscle	3/2619	16/18670	0.3939	0.599	0.4493	ATP1B1/KCNJ2/P2RX4	3
BP	GO:0061684	chaperone-mediated autophagy	3/2619	16/18670	0.3939	0.599	0.4493	SNCA/CLU/CTSA	3
BP	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade	3/2619	16/18670	0.3939	0.599	0.4493	CAMTA1/IGF1/CIB1	3
BP	GO:0071732	cellular response to nitric oxide	3/2619	16/18670	0.3939	0.599	0.4493	CCNA2/CFLAR/HNRNPD	3
BP	GO:0072176	nephric duct development	3/2619	16/18670	0.3939	0.599	0.4493	BMP4/WNT11/EPHA4	3
BP	GO:0080182	histone H3-K4 trimethylation	3/2619	16/18670	0.3939	0.599	0.4493	WDR61/ARID4A/OGT	3
BP	GO:0090083	regulation of inclusion body assembly	3/2619	16/18670	0.3939	0.599	0.4493	CLU/SNCAIP/HSPA2	3
BP	GO:0106058	positive regulation of calcineurin-mediated signaling	3/2619	16/18670	0.3939	0.599	0.4493	CAMTA1/IGF1/CIB1	3
BP	GO:1900242	regulation of synaptic vesicle endocytosis	3/2619	16/18670	0.3939	0.599	0.4493	SH3GL1/SYT11/ROCK1	3
BP	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	3/2619	16/18670	0.3939	0.599	0.4493	ING2/CD44/TAF9B	3
BP	GO:1903541	regulation of exosomal secretion	3/2619	16/18670	0.3939	0.599	0.4493	SDC1/IFNG/CHMP2A	3
BP	GO:1905153	regulation of membrane invagination	3/2619	16/18670	0.3939	0.599	0.4493	TREM2/SYT11/PPARG	3
BP	GO:1990000	amyloid fibril formation	3/2619	16/18670	0.3939	0.599	0.4493	CLU/APOE/CRYAB	3
BP	GO:2000369	regulation of clathrin-dependent endocytosis	3/2619	16/18670	0.3939	0.599	0.4493	SYT11/PIK3CB/HIP1R	3
BP	GO:0006278	RNA-dependent DNA biosynthetic process	12/2619	77/18670	0.3949	0.5999	0.45	MAPK3/ATR/TNKS2/ATM/NHP2/RPA1/DCP2/HMBOX1/AURKB/HNRNPA1/PRKCQ/RAD50	12
BP	GO:0008344	adult locomotory behavior	12/2619	77/18670	0.3949	0.5999	0.45	ZIC1/SNCA/TMOD1/UCHL1/ADAM22/EN1/EPHA4/HOXD9/ID2/NPC1/SEZ6L/PBX3	12
BP	GO:0031397	negative regulation of protein ubiquitination	12/2619	77/18670	0.3949	0.5999	0.45	TNFAIP3/DYSF/TRIP12/DNAJA1/ARRB1/TSPO/GLMN/OGT/N4BP1/CRY1/UBR5/FBXO5	12
BP	GO:0035050	embryonic heart tube development	12/2619	77/18670	0.3949	0.5999	0.45	NOTCH1/FOLR1/SMAD3/FOXC1/IFT52/C2CD3/MED1/BBS4/MICAL2/TMED2/HIF1A/SMO	12
BP	GO:1902803	regulation of synaptic vesicle transport	13/2619	84/18670	0.397	0.603	0.4523	RIMS3/PREPL/PRKCB/PFN2/PINK1/GSK3B/ADCY1/CACNB2/CACNA1D/SYT1/SYN1/RAP1B/NAPA	13
BP	GO:0035303	regulation of dephosphorylation	31/2619	209/18670	0.3979	0.6042	0.4532	PTN/JAK2/SEMA4D/SMAD3/CAMTA1/LILRB2/MTMR4/PTPRC/MTMR9/PINK1/GSK3B/PPP6R3/SET/RRP1B/MAGI2/SFI1/ROCK1/SHOC2/PPP4R1/PPP1R16B/CDH5/PPP1R12A/IFNG/MTMR1/MFHAS1/PIN1/ANKLE2/PHACTR4/ENSA/LGALS3/STYXL1	31
BP	GO:0006775	fat-soluble vitamin metabolic process	7/2619	43/18670	0.3989	0.605	0.4538	VKORC1/LGMN/CYP11A1/NFKB1/IFNG/CYP4F11/CBR1	7
BP	GO:0030866	cortical actin cytoskeleton organization	7/2619	43/18670	0.3989	0.605	0.4538	ECT2/EPB41L1/RACGAP1/ROCK1/WIPF1/RAB13/LLGL2	7
BP	GO:0038202	TORC1 signaling	7/2619	43/18670	0.3989	0.605	0.4538	ATM/RRAGA/SEC13/MLST8/RRAGD/SESN1/CLEC16A	7
BP	GO:0045773	positive regulation of axon extension	7/2619	43/18670	0.3989	0.605	0.4538	MACF1/VEGFA/GOLGA4/TRPV2/CDKL5/CYFIP1/DSCAM	7
BP	GO:0055026	negative regulation of cardiac muscle tissue development	7/2619	43/18670	0.3989	0.605	0.4538	JARID2/RBP4/RGS4/MAPK11/CTDP1/TBX5/FZD7	7
BP	GO:0099175	regulation of postsynapse organization	15/2619	98/18670	0.4004	0.6071	0.4554	PTN/CDH2/LILRB2/SLC7A11/PRNP/BAIAP2/APOE/SIPA1L1/SEMA3F/GHSR/EPHA4/CDKL5/CAPRIN2/CAMK2B/ACTR2	15
BP	GO:0015748	organophosphate ester transport	16/2619	105/18670	0.4017	0.609	0.4568	SLC25A4/ATP8B1/G6PC3/APOE/PITPNC1/OSBPL8/TMEM30A/PCTP/APOC1/ABCC1/SCP2/ATP8A1/ATP11B/ABCB1/ATP10A/STARD7	16
BP	GO:0003279	cardiac septum development	17/2619	112/18670	0.4028	0.6106	0.4579	NOTCH1/DHRS3/BMP4/WNT11/SNX17/MAML1/RBM15/ZFPM2/NOS3/TBX5/RBPJ/PRDM1/PLXND1/ID2/SMO/MYH10/FZD2	17
BP	GO:0032784	regulation of DNA-templated transcription, elongation	8/2619	50/18670	0.4032	0.6107	0.458	TCEA2/HTATSF1/WDR61/EZH2/THOC1/CCNT2/CCNK/CDK9	8
BP	GO:0042398	cellular modified amino acid biosynthetic process	8/2619	50/18670	0.4032	0.6107	0.458	GCH1/ALDH7A1/GAMT/SLC7A11/GATM/ALDH9A1/ACADM/GGCT	8
BP	GO:0097035	regulation of membrane lipid distribution	8/2619	50/18670	0.4032	0.6107	0.458	ATP8B1/TMEM30A/ABCC1/PLSCR4/ATP8A1/ATP11B/ABCB1/ATP10A	8
BP	GO:0009067	aspartate family amino acid biosynthetic process	4/2619	23/18670	0.4069	0.6139	0.4605	BHMT2/THNSL2/GOT1/ASNS	4
BP	GO:0009226	nucleotide-sugar biosynthetic process	4/2619	23/18670	0.4069	0.6139	0.4605	GNPDA1/MPI/GMDS/PMM1	4
BP	GO:0015813	L-glutamate transmembrane transport	4/2619	23/18670	0.4069	0.6139	0.4605	PRAF2/SLC7A11/ARL6IP5/SLC1A1	4
BP	GO:0032373	positive regulation of sterol transport	4/2619	23/18670	0.4069	0.6139	0.4605	NFKBIA/APOE/NR1H2/SCP2	4
BP	GO:0032376	positive regulation of cholesterol transport	4/2619	23/18670	0.4069	0.6139	0.4605	NFKBIA/APOE/NR1H2/SCP2	4
BP	GO:0035812	renal sodium excretion	4/2619	23/18670	0.4069	0.6139	0.4605	COMT/AGT/TAC1/CORIN	4
BP	GO:0043576	regulation of respiratory gaseous exchange	4/2619	23/18670	0.4069	0.6139	0.4605	FTO/SLC5A3/PBX3/PASK	4
BP	GO:0051349	positive regulation of lyase activity	4/2619	23/18670	0.4069	0.6139	0.4605	TIMP2/GUCA1A/NOS3/CACNA1D	4
BP	GO:0051570	regulation of histone H3-K9 methylation	4/2619	23/18670	0.4069	0.6139	0.4605	JARID2/DNMT1/KDM3A/ATRX	4
BP	GO:0051882	mitochondrial depolarization	4/2619	23/18670	0.4069	0.6139	0.4605	GOT1/TSPO/KDR/MYOC	4
BP	GO:0071294	cellular response to zinc ion	4/2619	23/18670	0.4069	0.6139	0.4605	KCNK3/TSPO/P2RX4/CREB1	4
BP	GO:0071425	hematopoietic stem cell proliferation	4/2619	23/18670	0.4069	0.6139	0.4605	PIM1/N4BP2L2/ETV6/BABAM1	4
BP	GO:0072170	metanephric tubule development	4/2619	23/18670	0.4069	0.6139	0.4605	STAT1/SOX9/ACAT1/CXCR2	4
BP	GO:0090343	positive regulation of cell aging	4/2619	23/18670	0.4069	0.6139	0.4605	HLA-G/KRAS/HMGA1/HMGA2	4
BP	GO:0097150	neuronal stem cell population maintenance	4/2619	23/18670	0.4069	0.6139	0.4605	NOTCH1/CDH2/ASPM/PCM1	4
BP	GO:1903429	regulation of cell maturation	4/2619	23/18670	0.4069	0.6139	0.4605	NPR2/GAL/BCL11A/TRIM58	4
BP	GO:0017156	calcium ion regulated exocytosis	23/2619	154/18670	0.407	0.6139	0.4605	NOTCH1/RPH3AL/SNCA/RIMS3/PREPL/PRKCB/SYT11/SDF4/SYNJ1/PFN2/GSK3B/SYT17/VAMP3/VAMP7/ADCY1/SCIN/VAMP2/CACNB2/CACNA1D/SYT1/SYN1/RAP1B/NAPA	23
BP	GO:0120032	regulation of plasma membrane bounded cell projection assembly	26/2619	175/18670	0.408	0.6141	0.4606	CEP135/CDC42EP3/ATP8B1/SYNE2/PFN2/RALA/KIT/SH3YL1/MNS1/PLD1/BBS4/RABEP2/PPP1R16B/GPM6A/AUTS2/RAC2/IFT140/ARHGAP35/CCR7/CYLD/VDAC3/CDKL5/EPS8L2/CYFIP1/PODXL/DYNC2LI1	26
BP	GO:0071804	cellular potassium ion transport	32/2619	217/18670	0.4089	0.6141	0.4606	ATP1B1/TREM2/KCNN3/SLC12A8/KCNQ1/KCNK15/NETO2/PRNP/SLC12A7/BIN1/MTMR6/KCNK3/KLHL24/KCNJ2/ANK3/RGS4/CD63/ABCC8/PKD2L1/VAMP2/KCNJ8/KCNN2/AKAP9/CACNA1D/GAL/CCT8L2/KCND1/FLNA/KCNQ3/KCNMB2/NEDD4L/DPP6	32
BP	GO:0071805	potassium ion transmembrane transport	32/2619	217/18670	0.4089	0.6141	0.4606	ATP1B1/TREM2/KCNN3/SLC12A8/KCNQ1/KCNK15/NETO2/PRNP/SLC12A7/BIN1/MTMR6/KCNK3/KLHL24/KCNJ2/ANK3/RGS4/CD63/ABCC8/PKD2L1/VAMP2/KCNJ8/KCNN2/AKAP9/CACNA1D/GAL/CCT8L2/KCND1/FLNA/KCNQ3/KCNMB2/NEDD4L/DPP6	32
BP	GO:0016197	endosomal transport	33/2619	224/18670	0.409	0.6141	0.4606	MICALL1/ARL4C/PREPL/MICALL2/VPS37C/ZFYVE16/PIKFYVE/BLOC1S1/ARL1/STX10/EHD3/VTI1B/DENND1B/SNX17/CHMP6/CMTM6/VAMP3/VPS16/SNX2/TRAPPC10/RAB13/CHMP2A/MAGEL2/ACAP2/TMEM50B/AP1S1/SORT1/DENND1C/UBB/ALMS1/CHMP1B/RAB11B/CLEC16A	33
BP	GO:0043297	apical junction assembly	10/2619	64/18670	0.4091	0.6141	0.4606	ECT2/MICALL2/ARL2/PRKCH/PECAM1/WNT11/ROCK1/PRKCI/RAB13/MTDH	10
BP	GO:1900449	regulation of glutamate receptor signaling pathway	10/2619	64/18670	0.4091	0.6141	0.4606	NETO2/PRNP/PINK1/KLHL24/GRIA2/ADRB2/IFNG/CRHBP/PTK2B/CCR2	10
BP	GO:1903672	positive regulation of sprouting angiogenesis	10/2619	64/18670	0.4091	0.6141	0.4606	ITGA5/JAK1/PPP1R16B/PLK2/S100A1/KDR/GHSR/VEGFA/MAP3K3/CIB1	10
BP	GO:0042273	ribosomal large subunit biogenesis	11/2619	71/18670	0.4112	0.6141	0.4606	NLE1/NHP2/AAMP/RPL12/MRPL11/MDN1/RPL10A/MRPL20/EIF6/RPL35A/RPLP0	11
BP	GO:0043647	inositol phosphate metabolic process	11/2619	71/18670	0.4112	0.6141	0.4606	PLCG2/SNCA/PTH1R/SYNJ1/GPER1/NUDT11/PLCE1/PLCD1/ISYNA1/INPP5E/PTK2B	11
BP	GO:0008306	associative learning	12/2619	78/18670	0.4129	0.6141	0.4606	LGMN/SLC7A11/B4GALT2/KIT/AGT/DEAF1/NRGN/HIF1A/TAC1/CREB1/KRAS/ACTR2	12
BP	GO:2000300	regulation of synaptic vesicle exocytosis	12/2619	78/18670	0.4129	0.6141	0.4606	RIMS3/PREPL/PRKCB/PFN2/GSK3B/ADCY1/CACNB2/CACNA1D/SYT1/SYN1/RAP1B/NAPA	12
BP	GO:1901532	regulation of hematopoietic progenitor cell differentiation	13/2619	85/18670	0.4143	0.6141	0.4606	NOTCH1/FOXC1/SOS1/PSMB9/N4BP2L2/PUS7/PSMC2/PSMB6/PSMC3/PSMD8/PSMB5/PSMD10/TCF3	13
BP	GO:0000038	very long-chain fatty acid metabolic process	5/2619	30/18670	0.4146	0.6141	0.4606	TECR/SLC27A6/SLC27A5/PEX2/ACOX1	5
BP	GO:0001844	protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	5/2619	30/18670	0.4146	0.6141	0.4606	BAD/GZMB/PPP1R13B/YWHAH/TP53BP2	5
BP	GO:0021696	cerebellar cortex morphogenesis	5/2619	30/18670	0.4146	0.6141	0.4606	RORA/AGTPBP1/ZNF365/HERC1/SMO	5
BP	GO:0043171	peptide catabolic process	5/2619	30/18670	0.4146	0.6141	0.4606	TRHDE/IDE/CPQ/LNPEP/ANPEP	5
BP	GO:0045940	positive regulation of steroid metabolic process	5/2619	30/18670	0.4146	0.6141	0.4606	APOE/IFNG/APOC1/AGT/PRKAA1	5
BP	GO:0045948	positive regulation of translational initiation	5/2619	30/18670	0.4146	0.6141	0.4606	CCL5/RXRA/POLR2G/DNAJC3/DAZL	5
BP	GO:0061842	microtubule organizing center localization	5/2619	30/18670	0.4146	0.6141	0.4606	NDE1/ASPM/SYNE2/RANBP2/AKAP9	5
BP	GO:0090200	positive regulation of release of cytochrome c from mitochondria	5/2619	30/18670	0.4146	0.6141	0.4606	FAM162A/BAD/PINK1/GPER1/CIDEB	5
BP	GO:0090314	positive regulation of protein targeting to membrane	5/2619	30/18670	0.4146	0.6141	0.4606	FIS1/PRNP/ERBB2/ANK3/CIB1	5
BP	GO:1903205	regulation of hydrogen peroxide-induced cell death	5/2619	30/18670	0.4146	0.6141	0.4606	HGF/PINK1/TRAP1/PYCR1/PSAP	5
BP	GO:1904893	negative regulation of STAT cascade	5/2619	30/18670	0.4146	0.6141	0.4606	SOCS1/PTPN2/NF2/GGNBP2/SH2B3	5
BP	GO:0045833	negative regulation of lipid metabolic process	14/2619	92/18670	0.4155	0.6141	0.4606	SIK1/SPHK1/FBXW7/ERLIN2/APOE/GPER1/NFKB1/APOC1/WDTC1/AKR1C3/PDGFB/SOD1/PRKAA1/CRTC3	14
BP	GO:0006342	chromatin silencing	18/2619	120/18670	0.4184	0.6141	0.4606	SMCHD1/DNMT1/UBR2/EZH2/ATF7IP/ATAD2B/MSL3/FAM172A/ARID1A/PCGF1/EED/HMGB1/SMARCA5/HDAC1/ATAD2/BAZ2A/HMGA1/MORF4L1	18
BP	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	18/2619	120/18670	0.4184	0.6141	0.4606	FOLR1/SMAD3/GOT1/MTMR4/ADAM17/TRIM33/HTRA1/ING2/ADAMTSL2/RNF111/ZNF451/CDKN1C/PIN1/UBB/FERMT1/LTBP4/EP300/HSPA5	18
BP	GO:0003183	mitral valve morphogenesis	2/2619	10/18670	0.4195	0.6141	0.4606	NOTCH1/TWIST1	2
BP	GO:0003376	sphingosine-1-phosphate receptor signaling pathway	2/2619	10/18670	0.4195	0.6141	0.4606	SPHK1/S1PR1	2
BP	GO:0006171	cAMP biosynthetic process	2/2619	10/18670	0.4195	0.6141	0.4606	ADCY1/ADCY2	2
BP	GO:0006285	base-excision repair, AP site formation	2/2619	10/18670	0.4195	0.6141	0.4606	TDG/MPG	2
BP	GO:0006547	histidine metabolic process	2/2619	10/18670	0.4195	0.6141	0.4606	HDC/HNMT	2
BP	GO:0006569	tryptophan catabolic process	2/2619	10/18670	0.4195	0.6141	0.4606	HAAO/IDO1	2
BP	GO:0006930	substrate-dependent cell migration, cell extension	2/2619	10/18670	0.4195	0.6141	0.4606	CTTN/MYH10	2
BP	GO:0007016	cytoskeletal anchoring at plasma membrane	2/2619	10/18670	0.4195	0.6141	0.4606	ANK3/TLN2	2
BP	GO:0007028	cytoplasm organization	2/2619	10/18670	0.4195	0.6141	0.4606	SOS1/ETV6	2
BP	GO:0007084	mitotic nuclear envelope reassembly	2/2619	10/18670	0.4195	0.6141	0.4606	BANF1/ANKLE2	2
BP	GO:0010739	positive regulation of protein kinase A signaling	2/2619	10/18670	0.4195	0.6141	0.4606	ADRB2/CALCR	2
BP	GO:0010918	positive regulation of mitochondrial membrane potential	2/2619	10/18670	0.4195	0.6141	0.4606	BAD/STOML2	2
BP	GO:0010998	regulation of translational initiation by eIF2 alpha phosphorylation	2/2619	10/18670	0.4195	0.6141	0.4606	NCK2/DNAJC3	2
BP	GO:0014877	response to muscle inactivity involved in regulation of muscle adaptation	2/2619	10/18670	0.4195	0.6141	0.4606	SGCA/MTMR4	2
BP	GO:0014894	response to denervation involved in regulation of muscle adaptation	2/2619	10/18670	0.4195	0.6141	0.4606	SGCA/MTMR4	2
BP	GO:0015809	arginine transport	2/2619	10/18670	0.4195	0.6141	0.4606	AGT/SLC11A1	2
BP	GO:0015937	coenzyme A biosynthetic process	2/2619	10/18670	0.4195	0.6141	0.4606	ACAT1/PANK3	2
BP	GO:0018026	peptidyl-lysine monomethylation	2/2619	10/18670	0.4195	0.6141	0.4606	SMYD2/SETD2	2
BP	GO:0018065	protein-cofactor linkage	2/2619	10/18670	0.4195	0.6141	0.4606	GLRX5/LIPT1	2
BP	GO:0021877	forebrain neuron fate commitment	2/2619	10/18670	0.4195	0.6141	0.4606	BCL11B/SATB2	2
BP	GO:0021936	regulation of cerebellar granule cell precursor proliferation	2/2619	10/18670	0.4195	0.6141	0.4606	EGF/SMO	2
BP	GO:0031284	positive regulation of guanylate cyclase activity	2/2619	10/18670	0.4195	0.6141	0.4606	GUCA1A/NOS3	2
BP	GO:0031848	protection from non-homologous end joining at telomere	2/2619	10/18670	0.4195	0.6141	0.4606	DCLRE1C/ERCC1	2
BP	GO:0032025	response to cobalt ion	2/2619	10/18670	0.4195	0.6141	0.4606	CASP9/SERPINF1	2
BP	GO:0032275	luteinizing hormone secretion	2/2619	10/18670	0.4195	0.6141	0.4606	TACR2/TMF1	2
BP	GO:0032308	positive regulation of prostaglandin secretion	2/2619	10/18670	0.4195	0.6141	0.4606	TNFRSF11A/P2RX4	2
BP	GO:0033131	regulation of glucokinase activity	2/2619	10/18670	0.4195	0.6141	0.4606	BAD/RANBP2	2
BP	GO:0033210	leptin-mediated signaling pathway	2/2619	10/18670	0.4195	0.6141	0.4606	BBS4/UGCG	2
BP	GO:0034135	regulation of toll-like receptor 2 signaling pathway	2/2619	10/18670	0.4195	0.6141	0.4606	TNFAIP3/MFHAS1	2
BP	GO:0034350	regulation of glial cell apoptotic process	2/2619	10/18670	0.4195	0.6141	0.4606	PRKCH/PRKCI	2
BP	GO:0034454	microtubule anchoring at centrosome	2/2619	10/18670	0.4195	0.6141	0.4606	BBS4/PCM1	2
BP	GO:0034770	histone H4-K20 methylation	2/2619	10/18670	0.4195	0.6141	0.4606	ARID4B/ARID4A	2
BP	GO:0035090	maintenance of apical/basal cell polarity	2/2619	10/18670	0.4195	0.6141	0.4606	WNT11/LIN7B	2
BP	GO:0035768	endothelial cell chemotaxis to fibroblast growth factor	2/2619	10/18670	0.4195	0.6141	0.4606	CXCL13/FGF18	2
BP	GO:0035845	photoreceptor cell outer segment organization	2/2619	10/18670	0.4195	0.6141	0.4606	BBS4/IFT140	2
BP	GO:0035865	cellular response to potassium ion	2/2619	10/18670	0.4195	0.6141	0.4606	CRHBP/SOD1	2
BP	GO:0035878	nail development	2/2619	10/18670	0.4195	0.6141	0.4606	PRKAB1/FZD6	2
BP	GO:0035999	tetrahydrofolate interconversion	2/2619	10/18670	0.4195	0.6141	0.4606	MTHFD2/TYMS	2
BP	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway	2/2619	10/18670	0.4195	0.6141	0.4606	COL4A1/COL4A2	2
BP	GO:0042436	indole-containing compound catabolic process	2/2619	10/18670	0.4195	0.6141	0.4606	HAAO/IDO1	2
BP	GO:0042756	drinking behavior	2/2619	10/18670	0.4195	0.6141	0.4606	AGT/EN1	2
BP	GO:0042989	sequestering of actin monomers	2/2619	10/18670	0.4195	0.6141	0.4606	SCIN/TMSB10	2
BP	GO:0043653	mitochondrial fragmentation involved in apoptotic process	2/2619	10/18670	0.4195	0.6141	0.4606	FIS1/ERBB4	2
BP	GO:0045199	maintenance of epithelial cell apical/basal polarity	2/2619	10/18670	0.4195	0.6141	0.4606	WNT11/LIN7B	2
BP	GO:0045988	negative regulation of striated muscle contraction	2/2619	10/18670	0.4195	0.6141	0.4606	SRI/BIN1	2
BP	GO:0046218	indolalkylamine catabolic process	2/2619	10/18670	0.4195	0.6141	0.4606	HAAO/IDO1	2
BP	GO:0046642	negative regulation of alpha-beta T cell proliferation	2/2619	10/18670	0.4195	0.6141	0.4606	TNFRSF14/XCL1	2
BP	GO:0048149	behavioral response to ethanol	2/2619	10/18670	0.4195	0.6141	0.4606	USP46/CRHBP	2
BP	GO:0048262	determination of dorsal/ventral asymmetry	2/2619	10/18670	0.4195	0.6141	0.4606	NBL1/DDIT3	2
BP	GO:0051006	positive regulation of lipoprotein lipase activity	2/2619	10/18670	0.4195	0.6141	0.4606	NR1H2/LMF1	2
BP	GO:0051133	regulation of NK T cell activation	2/2619	10/18670	0.4195	0.6141	0.4606	HSPH1/IL6R	2
BP	GO:0060033	anatomical structure regression	2/2619	10/18670	0.4195	0.6141	0.4606	LEF1/NINJ1	2
BP	GO:0060281	regulation of oocyte development	2/2619	10/18670	0.4195	0.6141	0.4606	NPR2/IGF1	2
BP	GO:0060346	bone trabecula formation	2/2619	10/18670	0.4195	0.6141	0.4606	SFRP1/CHAD	2
BP	GO:0060456	positive regulation of digestive system process	2/2619	10/18670	0.4195	0.6141	0.4606	GHSR/TAC1	2
BP	GO:0060513	prostatic bud formation	2/2619	10/18670	0.4195	0.6141	0.4606	AR/BMP4	2
BP	GO:0061140	lung secretory cell differentiation	2/2619	10/18670	0.4195	0.6141	0.4606	AIMP2/HOXA5	2
BP	GO:0061299	retina vasculature morphogenesis in camera-type eye	2/2619	10/18670	0.4195	0.6141	0.4606	LRP5/COL4A1	2
BP	GO:0061635	regulation of protein complex stability	2/2619	10/18670	0.4195	0.6141	0.4606	TAPBP/TRAPPC11	2
BP	GO:0070091	glucagon secretion	2/2619	10/18670	0.4195	0.6141	0.4606	IL6/PASK	2
BP	GO:0070341	fat cell proliferation	2/2619	10/18670	0.4195	0.6141	0.4606	FTO/PID1	2
BP	GO:0070344	regulation of fat cell proliferation	2/2619	10/18670	0.4195	0.6141	0.4606	FTO/PID1	2
BP	GO:0070391	response to lipoteichoic acid	2/2619	10/18670	0.4195	0.6141	0.4606	TREM2/RIPK2	2
BP	GO:0070472	regulation of uterine smooth muscle contraction	2/2619	10/18670	0.4195	0.6141	0.4606	TACR2/GPER1	2
BP	GO:0071223	cellular response to lipoteichoic acid	2/2619	10/18670	0.4195	0.6141	0.4606	TREM2/RIPK2	2
BP	GO:0071281	cellular response to iron ion	2/2619	10/18670	0.4195	0.6141	0.4606	HFE/CCNB1	2
BP	GO:0071501	cellular response to sterol depletion	2/2619	10/18670	0.4195	0.6141	0.4606	FBXW7/ERLIN2	2
BP	GO:0071600	otic vesicle morphogenesis	2/2619	10/18670	0.4195	0.6141	0.4606	SOX9/CEP290	2
BP	GO:0075522	IRES-dependent viral translational initiation	2/2619	10/18670	0.4195	0.6141	0.4606	EIF3A/EIF2D	2
BP	GO:0090309	positive regulation of methylation-dependent chromatin silencing	2/2619	10/18670	0.4195	0.6141	0.4606	DNMT1/ATF7IP	2
BP	GO:0090557	establishment of endothelial intestinal barrier	2/2619	10/18670	0.4195	0.6141	0.4606	RAP2C/TJP2	2
BP	GO:0097048	dendritic cell apoptotic process	2/2619	10/18670	0.4195	0.6141	0.4606	AXL/CCR7	2
BP	GO:0097050	type B pancreatic cell apoptotic process	2/2619	10/18670	0.4195	0.6141	0.4606	IL6/TCF7L2	2
BP	GO:0097278	complement-dependent cytotoxicity	2/2619	10/18670	0.4195	0.6141	0.4606	RAB27A/CD59	2
BP	GO:1900122	positive regulation of receptor binding	2/2619	10/18670	0.4195	0.6141	0.4606	HFE/BDNF	2
BP	GO:1900222	negative regulation of amyloid-beta clearance	2/2619	10/18670	0.4195	0.6141	0.4606	LRPAP1/IFNG	2
BP	GO:1902033	regulation of hematopoietic stem cell proliferation	2/2619	10/18670	0.4195	0.6141	0.4606	PIM1/N4BP2L2	2
BP	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA	2/2619	10/18670	0.4195	0.6141	0.4606	PPP3CA/NCOR1	2
BP	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA	2/2619	10/18670	0.4195	0.6141	0.4606	EGFR/BMP4	2
BP	GO:1904779	regulation of protein localization to centrosome	2/2619	10/18670	0.4195	0.6141	0.4606	GSK3B/NUP62	2
BP	GO:1904896	ESCRT complex disassembly	2/2619	10/18670	0.4195	0.6141	0.4606	CHMP2A/CHMP1B	2
BP	GO:1904903	ESCRT III complex disassembly	2/2619	10/18670	0.4195	0.6141	0.4606	CHMP2A/CHMP1B	2
BP	GO:1905879	regulation of oogenesis	2/2619	10/18670	0.4195	0.6141	0.4606	NPR2/IGF1	2
BP	GO:1990253	cellular response to leucine starvation	2/2619	10/18670	0.4195	0.6141	0.4606	RRAGD/SESN1	2
BP	GO:1990535	neuron projection maintenance	2/2619	10/18670	0.4195	0.6141	0.4606	PRNP/INSR	2
BP	GO:2000035	regulation of stem cell division	2/2619	10/18670	0.4195	0.6141	0.4606	NCOA3/NAP1L2	2
BP	GO:2000253	positive regulation of feeding behavior	2/2619	10/18670	0.4195	0.6141	0.4606	GHSR/AGRP	2
BP	GO:2000271	positive regulation of fibroblast apoptotic process	2/2619	10/18670	0.4195	0.6141	0.4606	SFRP1/STK17B	2
BP	GO:2000317	negative regulation of T-helper 17 type immune response	2/2619	10/18670	0.4195	0.6141	0.4606	IL27RA/RC3H2	2
BP	GO:2000425	regulation of apoptotic cell clearance	2/2619	10/18670	0.4195	0.6141	0.4606	TREM2/HMGB1	2
BP	GO:2000544	regulation of endothelial cell chemotaxis to fibroblast growth factor	2/2619	10/18670	0.4195	0.6141	0.4606	CXCL13/FGF18	2
BP	GO:2000574	regulation of microtubule motor activity	2/2619	10/18670	0.4195	0.6141	0.4606	DNAL4/NDE1	2
BP	GO:2000628	regulation of miRNA metabolic process	2/2619	10/18670	0.4195	0.6141	0.4606	RC3H2/NFKB1	2
BP	GO:2000668	regulation of dendritic cell apoptotic process	2/2619	10/18670	0.4195	0.6141	0.4606	AXL/CCR7	2
BP	GO:2000833	positive regulation of steroid hormone secretion	2/2619	10/18670	0.4195	0.6141	0.4606	TAC1/GAL	2
BP	GO:2001214	positive regulation of vasculogenesis	2/2619	10/18670	0.4195	0.6141	0.4606	TMEM100/KDR	2
BP	GO:0051668	localization within membrane	22/2619	148/18670	0.4197	0.6141	0.4606	PTN/ATP1B1/CDH2/SEC24A/USP46/SLC7A11/PTPRC/RFTN1/ITGAL/APOE/RALA/MAGI2/ITGB7/SEC13/ADAM22/CD81/KIF5C/GHSR/TYROBP/NDC1/CD2/FLNA	22
BP	GO:0001662	behavioral fear response	6/2619	37/18670	0.4197	0.6141	0.4606	BRINP1/USP46/APOE/PENK/DEAF1/VDAC3	6
BP	GO:0021587	cerebellum morphogenesis	6/2619	37/18670	0.4197	0.6141	0.4606	RORA/AGTPBP1/ZNF365/HERC1/SMO/HSPA5	6
BP	GO:0046006	regulation of activated T cell proliferation	6/2619	37/18670	0.4197	0.6141	0.4606	BTN2A2/IGFBP2/PRNP/IGF1/HMGB1/IL6R	6
BP	GO:0050691	regulation of defense response to virus by host	6/2619	37/18670	0.4197	0.6141	0.4606	TNFAIP3/AIM2/STAT1/IL15/MICB/MMP12	6
BP	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	6/2619	37/18670	0.4197	0.6141	0.4606	NEDD9/ARHGEF7/MYOC/HAS2/CIB1/FLNA	6
BP	GO:1903432	regulation of TORC1 signaling	6/2619	37/18670	0.4197	0.6141	0.4606	ATM/RRAGA/SEC13/RRAGD/SESN1/CLEC16A	6
BP	GO:0014003	oligodendrocyte development	7/2619	44/18670	0.4232	0.6181	0.4636	CLU/ID4/ERCC2/FA2H/ID2/PLP1/TENM4	7
BP	GO:0014047	glutamate secretion	7/2619	44/18670	0.4232	0.6181	0.4636	SNCA/SLC38A2/NTRK2/HRH3/VAMP2/SYT1/SLC1A1	7
BP	GO:0030225	macrophage differentiation	7/2619	44/18670	0.4232	0.6181	0.4636	CEBPA/IL15/BMP4/PTPN2/TRIB1/VEGFA/ID2	7
BP	GO:0032965	regulation of collagen biosynthetic process	7/2619	44/18670	0.4232	0.6181	0.4636	GOT1/BMP4/PPARG/F2R/IL6/SUCO/LARP6	7
BP	GO:0042269	regulation of natural killer cell mediated cytotoxicity	7/2619	44/18670	0.4232	0.6181	0.4636	RASGRP1/HLA-F/HLA-G/MICB/HLA-E/CRTAM/ULBP2	7
BP	GO:0050654	chondroitin sulfate proteoglycan metabolic process	7/2619	44/18670	0.4232	0.6181	0.4636	NDNF/HEXA/CHST15/SPOCK2/VCAN/CHST12/ARSB	7
BP	GO:0061756	leukocyte adhesion to vascular endothelial cell	7/2619	44/18670	0.4232	0.6181	0.4636	CX3CR1/SELE/ROCK1/ITGB7/ELANE/GOLPH3/CCR2	7
BP	GO:1903214	regulation of protein targeting to mitochondrion	7/2619	44/18670	0.4232	0.6181	0.4636	FBXW7/MICALL2/PINK1/RAC2/ATG13/PRKAA1/UBL5	7
BP	GO:0032007	negative regulation of TOR signaling	8/2619	51/18670	0.4258	0.6217	0.4663	SIK1/UBR2/DDIT4/ATM/DEPTOR/HIF1A/PRKAA1/SESN1	8
BP	GO:0031060	regulation of histone methylation	10/2619	65/18670	0.4291	0.6263	0.4697	MTF2/JARID2/WDR61/DNMT1/KDM3A/AUTS2/ATRX/EED/PAXBP1/OGT	10
BP	GO:1901016	regulation of potassium ion transmembrane transporter activity	10/2619	65/18670	0.4291	0.6263	0.4697	ATP1B1/TREM2/NETO2/KLHL24/ANK3/VAMP2/AKAP9/CACNA1D/GAL/NEDD4L	10
BP	GO:1902036	regulation of hematopoietic stem cell differentiation	11/2619	72/18670	0.4302	0.6267	0.47	FOXC1/PSMB9/N4BP2L2/PUS7/PSMC2/PSMB6/PSMC3/PSMD8/PSMB5/PSMD10/TCF3	11
BP	GO:0030193	regulation of blood coagulation	12/2619	79/18670	0.431	0.6267	0.47	VKORC1/PROS1/SERPINE1/APOE/TFPI/F2R/NOS3/PDGFB/PRKCQ/PRDX2/KRT1/SH2B3	12
BP	GO:0001935	endothelial cell proliferation	28/2619	191/18670	0.4317	0.6267	0.47	DYSF/STAT1/PRKD2/PGF/THBS4/ADAM17/APOE/PRKX/BMP4/HTR2B/TNMD/PPARG/PPP1R16B/KRIT1/PIK3CB/KDR/ANG/GHSR/PDGFB/VEGFA/HMGB1/SCG2/HIF1A/NGFR/STAT5A/XBP1/VEGFB/NRAS	28
BP	GO:0006333	chromatin assembly or disassembly	28/2619	191/18670	0.4317	0.6267	0.47	NAP1L3/SMCHD1/SOX9/NAP1L2/SMARCD3/SART3/SET/TPR/HIRIP3/ARID1A/DAXX/NASP/ATRX/PBRM1/HJURP/CENPT/CHD3/KAT6A/SMARCA5/SMARCD2/TSPYL1/PADI2/SUV39H2/CENPC/TSPYL5/UBN1/HMGA1/HMGA2	28
BP	GO:0060491	regulation of cell projection assembly	26/2619	177/18670	0.4322	0.6267	0.47	CEP135/CDC42EP3/ATP8B1/SYNE2/PFN2/RALA/KIT/SH3YL1/MNS1/PLD1/BBS4/RABEP2/PPP1R16B/GPM6A/AUTS2/RAC2/IFT140/ARHGAP35/CCR7/CYLD/VDAC3/CDKL5/EPS8L2/CYFIP1/PODXL/DYNC2LI1	26
BP	GO:0071772	response to BMP	25/2619	170/18670	0.4324	0.6267	0.47	SFRP1/NOTCH1/SOX9/MAPK3/TMEM100/HIVEP1/ZFYVE16/NEO1/TRIM33/HFE/HTRA1/BMP4/GDF5/LEF1/TNMD/FKBP8/CDH5/COMP/NBL1/EGR1/RBPJ/CHRDL1/USP9X/GDF9/ZNF423	25
BP	GO:0071773	cellular response to BMP stimulus	25/2619	170/18670	0.4324	0.6267	0.47	SFRP1/NOTCH1/SOX9/MAPK3/TMEM100/HIVEP1/ZFYVE16/NEO1/TRIM33/HFE/HTRA1/BMP4/GDF5/LEF1/TNMD/FKBP8/CDH5/COMP/NBL1/EGR1/RBPJ/CHRDL1/USP9X/GDF9/ZNF423	25
BP	GO:0030301	cholesterol transport	15/2619	100/18670	0.4325	0.6267	0.47	NFKBIA/LIPC/CLU/APOM/EGF/APOE/PPARG/NFKB1/APOC1/TSPO/NR1H2/SCP2/ABCA2/LIMA1/NPC1	15
BP	GO:0036503	ERAD pathway	15/2619	100/18670	0.4325	0.6267	0.47	SDF2/HERPUD1/ERLIN2/UBE2J1/DNAJB14/RCN3/FBXO17/UBXN4/ANKZF1/MAN1B1/EDEM1/UBXN8/HSPA5/SEL1L/USP14	15
BP	GO:0099173	postsynapse organization	24/2619	163/18670	0.4326	0.6267	0.47	PTN/LGMN/CDH2/LILRB2/SLC7A11/DOCK10/PRNP/BAIAP2/ZNF365/APOE/INSR/MAGI2/SIPA1L1/SEMA3F/GHSR/EPHA4/CHRNB1/CTTN/CDKL5/CAPRIN2/ACTN1/CAMK2B/ACTR2/MYH10	24
BP	GO:0043535	regulation of blood vessel endothelial cell migration	23/2619	156/18670	0.4327	0.6267	0.47	NOTCH1/PRKD2/FBXW7/ANGPT1/ADAM17/ANGPT2/APOE/CSNK2B/PPARG/CD40/HSPB1/PLK2/NOS3/FGF18/KDR/PDGFB/VEGFA/P2RX4/HMGB1/MAP3K3/HIF1A/CIB1/STAT5A	23
BP	GO:0014074	response to purine-containing compound	22/2619	149/18670	0.4328	0.6267	0.47	STAT1/IGFBP5/KCNQ1/NDUFS4/SDC1/BSG/STC1/BIRC2/FDX1/PENK/PPARG/ITPR2/ASS1/CRHBP/CPS1/P2RX4/SOD1/AKAP9/PRKAA1/PTK2B/RAP1B/HSPA5	22
BP	GO:0005976	polysaccharide metabolic process	17/2619	114/18670	0.4329	0.6267	0.47	PPP1R3C/ENPP1/EGF/PGM1/EXT2/GSK3B/INSR/DYRK2/PYGM/NFKB1/EXTL2/IGF1/PDGFB/GAA/HAS2/PASK/SORBS1	17
BP	GO:0032543	mitochondrial translation	20/2619	135/18670	0.433	0.6267	0.47	MTRF1/UQCC1/MRPL24/MRPL11/RMND1/MRPL40/MRPL23/GFM1/COA3/MRPS33/MRPS28/MRPS17/MRPS22/MRPS11/MRPL17/MRPL20/NGRN/MRPL18/MRPS14/MRPL4	20
BP	GO:0009855	determination of bilateral symmetry	19/2619	128/18670	0.433	0.6267	0.47	NOTCH1/FOLR1/GALNT11/SMAD3/AP1B1/IFT52/C2CD3/BBS4/MICAL2/FOXF1/NBL1/PSKH1/IFT140/TMED2/HIF1A/SMO/OFD1/DDIT3/DYNC2LI1	19
BP	GO:0051291	protein heterooligomerization	19/2619	128/18670	0.433	0.6267	0.47	GCH1/GCHFR/BIRC3/PCBD1/INSR/KRT10/BIRC2/RRM2/IDE/PRKAB1/MAGI2/CPSF7/CHMP2A/HBB/PRKAA1/KRT1/BCL10/SYT1/NUP62	19
BP	GO:0000963	mitochondrial RNA processing	3/2619	17/18670	0.4338	0.6267	0.47	HSD17B10/PUS1/TRMT5	3
BP	GO:0001522	pseudouridine synthesis	3/2619	17/18670	0.4338	0.6267	0.47	NHP2/PUS7/PUS1	3
BP	GO:0002693	positive regulation of cellular extravasation	3/2619	17/18670	0.4338	0.6267	0.47	PLVAP/ELANE/CCR2	3
BP	GO:0003184	pulmonary valve morphogenesis	3/2619	17/18670	0.4338	0.6267	0.47	NOTCH1/BMP4/NOS3	3
BP	GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	3/2619	17/18670	0.4338	0.6267	0.47	NOTCH1/TMEM100/RBPJ	3
BP	GO:0006266	DNA ligation	3/2619	17/18670	0.4338	0.6267	0.47	PARP3/HMGB1/TOP2A	3
BP	GO:0006744	ubiquinone biosynthetic process	3/2619	17/18670	0.4338	0.6267	0.47	COQ6/COQ9/COQ2	3
BP	GO:0021783	preganglionic parasympathetic fiber development	3/2619	17/18670	0.4338	0.6267	0.47	SIX1/SEMA3A/SEMA3F	3
BP	GO:0030011	maintenance of cell polarity	3/2619	17/18670	0.4338	0.6267	0.47	GSK3B/WNT11/LIN7B	3
BP	GO:0031268	pseudopodium organization	3/2619	17/18670	0.4338	0.6267	0.47	CDC42EP3/KIT/CCR7	3
BP	GO:0032966	negative regulation of collagen biosynthetic process	3/2619	17/18670	0.4338	0.6267	0.47	GOT1/PPARG/IL6	3
BP	GO:0036149	phosphatidylinositol acyl-chain remodeling	3/2619	17/18670	0.4338	0.6267	0.47	PLA2G2D/PLA2G4C/PLBD1	3
BP	GO:0043373	CD4-positive, alpha-beta T cell lineage commitment	3/2619	17/18670	0.4338	0.6267	0.47	LY9/IL6/BATF	3
BP	GO:0043649	dicarboxylic acid catabolic process	3/2619	17/18670	0.4338	0.6267	0.47	GOT1/DDO/ACOT8	3
BP	GO:0045324	late endosome to vacuole transport	3/2619	17/18670	0.4338	0.6267	0.47	CHMP2A/TMEM50B/CHMP1B	3
BP	GO:0046068	cGMP metabolic process	3/2619	17/18670	0.4338	0.6267	0.47	RORA/PDE1A/NPR2	3
BP	GO:0048243	norepinephrine secretion	3/2619	17/18670	0.4338	0.6267	0.47	HRH3/AGT/GHSR	3
BP	GO:0048532	anatomical structure arrangement	3/2619	17/18670	0.4338	0.6267	0.47	SEMA3A/SEMA3F/HSPA5	3
BP	GO:0051709	regulation of killing of cells of other organism	3/2619	17/18670	0.4338	0.6267	0.47	BAD/PRF1/IFNG	3
BP	GO:0060263	regulation of respiratory burst	3/2619	17/18670	0.4338	0.6267	0.47	SLAMF8/INSR/RAC2	3
BP	GO:0061318	renal filtration cell differentiation	3/2619	17/18670	0.4338	0.6267	0.47	BMP4/MAGI2/PODXL	3
BP	GO:0062033	positive regulation of mitotic sister chromatid segregation	3/2619	17/18670	0.4338	0.6267	0.47	NIPBL/DLGAP5/SMC5	3
BP	GO:0070242	thymocyte apoptotic process	3/2619	17/18670	0.4338	0.6267	0.47	ADA/BMP4/HIF1A	3
BP	GO:0071850	mitotic cell cycle arrest	3/2619	17/18670	0.4338	0.6267	0.47	MAGI2/CDC14A/CDKN1A	3
BP	GO:0072112	glomerular visceral epithelial cell differentiation	3/2619	17/18670	0.4338	0.6267	0.47	BMP4/MAGI2/PODXL	3
BP	GO:1901663	quinone biosynthetic process	3/2619	17/18670	0.4338	0.6267	0.47	COQ6/COQ9/COQ2	3
BP	GO:1904380	endoplasmic reticulum mannose trimming	3/2619	17/18670	0.4338	0.6267	0.47	MAN1B1/EDEM1/SEL1L	3
BP	GO:1905331	negative regulation of morphogenesis of an epithelium	3/2619	17/18670	0.4338	0.6267	0.47	STAT1/BMP4/CLASP1	3
BP	GO:0015850	organic hydroxy compound transport	38/2619	262/18670	0.4387	0.6335	0.4751	NFKBIA/SLC18A2/LIPC/SNCA/CLU/OSBPL3/APOM/SYT11/ATP8B1/RBP4/GRAMD1C/EGF/PINK1/APOE/SLC27A5/RXRA/FGF20/OSBPL8/SLC5A3/PPARG/HRH3/SYT17/NFKB1/APOC1/AGT/TSPO/NR1H2/GHSR/SCP2/ABCA2/TMF1/AQP2/TAC1/GAL/SYT1/LIMA1/AKR1C4/NPC1	38
BP	GO:0015931	nucleobase-containing compound transport	35/2619	241/18670	0.4401	0.6335	0.4751	CETN2/HNRNPA2B1/SLC25A4/SLC29A1/NXF3/NUP160/RFTN1/IGF2BP3/THOC2/NUP153/DDX39A/SLC35A2/THOC1/TPR/NUP50/SEC13/NMD3/RANBP2/NXF1/KIF5C/SNUPN/SRSF4/NUP210/HNRNPA1/SFPQ/NUP43/NDC1/SETD2/YTHDC1/NCBP2/EIF6/MVP/MRPL18/NUP98/NUP62	35
BP	GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	35/2619	241/18670	0.4401	0.6335	0.4751	SFRP1/NOTCH1/FOLR1/SMAD3/GOT1/MTMR4/ADAM17/NEO1/TRIM33/HFE/HTRA1/ING2/BMP4/GDF5/MAGI2/ADAMTSL2/RNF111/CSNK2B/ZNF451/FKBP8/CDH5/NBL1/CDKN1C/CILP/RBPJ/CHRDL1/PIN1/UBB/FERMT1/LTBP4/GDF9/EP300/INHBB/HSPA5/ZNF423	35
BP	GO:0001783	B cell apoptotic process	4/2619	24/18670	0.4403	0.6335	0.4751	TNFRSF21/ADA/AURKB/BCL10	4
BP	GO:0010288	response to lead ion	4/2619	24/18670	0.4403	0.6335	0.4751	QDPR/CDK4/CAT/CPOX	4
BP	GO:0014850	response to muscle activity	4/2619	24/18670	0.4403	0.6335	0.4751	FIS1/POSTN/AGT/HIF1A	4
BP	GO:0021544	subpallium development	4/2619	24/18670	0.4403	0.6335	0.4751	SLC7A11/BCL11B/BBS4/ALDH1A3	4
BP	GO:0021904	dorsal/ventral neural tube patterning	4/2619	24/18670	0.4403	0.6335	0.4751	TCTN1/BMP4/FKBP8/SMO	4
BP	GO:0036010	protein localization to endosome	4/2619	24/18670	0.4403	0.6335	0.4751	MICALL1/EGF/TMEM30A/TOLLIP	4
BP	GO:0036315	cellular response to sterol	4/2619	24/18670	0.4403	0.6335	0.4751	RORA/GRAMD1C/NFE2L1/SMO	4
BP	GO:0042104	positive regulation of activated T cell proliferation	4/2619	24/18670	0.4403	0.6335	0.4751	IGFBP2/IGF1/HMGB1/IL6R	4
BP	GO:0043302	positive regulation of leukocyte degranulation	4/2619	24/18670	0.4403	0.6335	0.4751	HLA-F/IL4R/FGR/VAMP7	4
BP	GO:0045603	positive regulation of endothelial cell differentiation	4/2619	24/18670	0.4403	0.6335	0.4751	NOTCH1/TMEM100/BMP4/CDH5	4
BP	GO:0046174	polyol catabolic process	4/2619	24/18670	0.4403	0.6335	0.4751	SYNJ1/SORD/GK/INPP5E	4
BP	GO:0046835	carbohydrate phosphorylation	4/2619	24/18670	0.4403	0.6335	0.4751	FGGY/RBKS/GNPTAB/PFKFB3	4
BP	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process	4/2619	24/18670	0.4403	0.6335	0.4751	ENPP1/TPST1/SULT1A2/PAPSS1	4
BP	GO:0062009	secondary palate development	4/2619	24/18670	0.4403	0.6335	0.4751	WNT11/LEF1/JAG2/FZD2	4
BP	GO:1904376	negative regulation of protein localization to cell periphery	4/2619	24/18670	0.4403	0.6335	0.4751	GBP1/PID1/AP2M1/TMEM59	4
BP	GO:0048839	inner ear development	28/2619	192/18670	0.4433	0.6368	0.4776	ZIC1/SIX1/NOTCH1/CEBPA/SOX9/KCNQ1/CCNA2/ATP8B1/BMP4/FGF20/KCNK3/FZD3/NAGLU/MCOLN3/RBPJ/EPHA4/ALDH1A3/LGR5/MAPKAPK2/SOD1/JAG2/MAF/MPV17/CEP290/FZD6/SLC4A7/PSAP/FZD2	28
BP	GO:0002675	positive regulation of acute inflammatory response	5/2619	31/18670	0.4439	0.6368	0.4776	TNFRSF11A/HLA-E/IL6/CCR7/TAC1	5
BP	GO:0006658	phosphatidylserine metabolic process	5/2619	31/18670	0.4439	0.6368	0.4776	PLA2G2D/OSBPL8/SERINC5/PLA1A/LPCAT4	5
BP	GO:0006691	leukotriene metabolic process	5/2619	31/18670	0.4439	0.6368	0.4776	LTC4S/ALOX5AP/MGST3/ABCC1/MAPKAPK2	5
BP	GO:0010543	regulation of platelet activation	5/2619	31/18670	0.4439	0.6368	0.4776	APOE/NOS3/PDGFB/PRKCQ/SH2B3	5
BP	GO:0032786	positive regulation of DNA-templated transcription, elongation	5/2619	31/18670	0.4439	0.6368	0.4776	WDR61/THOC1/CCNT2/CCNK/CDK9	5
BP	GO:0033687	osteoblast proliferation	5/2619	31/18670	0.4439	0.6368	0.4776	SFRP1/NELL1/SMAD3/ATRAID/OSR2	5
BP	GO:0036257	multivesicular body organization	5/2619	31/18670	0.4439	0.6368	0.4776	VPS37C/RAB27A/CHMP6/CHMP2A/CHMP1B	5
BP	GO:0040020	regulation of meiotic nuclear division	5/2619	31/18670	0.4439	0.6368	0.4776	CDC20/RAD1/PIWIL2/DAZL/FBXO5	5
BP	GO:0060292	long-term synaptic depression	5/2619	31/18670	0.4439	0.6368	0.4776	ABHD6/LILRB2/CD38/PLK2/PTK2B	5
BP	GO:0090075	relaxation of muscle	5/2619	31/18670	0.4439	0.6368	0.4776	ATP1B1/SRI/KCNJ2/P2RX4/SOD1	5
BP	GO:0099625	ventricular cardiac muscle cell membrane repolarization	5/2619	31/18670	0.4439	0.6368	0.4776	SCN1B/SNTA1/KCNQ1/KCNJ8/AKAP9	5
BP	GO:1902253	regulation of intrinsic apoptotic signaling pathway by p53 class mediator	5/2619	31/18670	0.4439	0.6368	0.4776	ING2/HNRNPK/CD44/TAF9B/UBB	5
BP	GO:0030509	BMP signaling pathway	23/2619	157/18670	0.4456	0.639	0.4793	SFRP1/NOTCH1/MAPK3/TMEM100/HIVEP1/ZFYVE16/NEO1/TRIM33/HFE/HTRA1/BMP4/GDF5/LEF1/FKBP8/CDH5/COMP/NBL1/EGR1/RBPJ/CHRDL1/USP9X/GDF9/ZNF423	23
BP	GO:0007190	activation of adenylate cyclase activity	6/2619	38/18670	0.4461	0.6391	0.4794	ADORA3/ADRB2/ADCY1/LGR5/ADCY2/RAF1	6
BP	GO:0046676	negative regulation of insulin secretion	6/2619	38/18670	0.4461	0.6391	0.4794	SFRP1/HADH/MAP4K4/GHSR/PPP3CA/INHBB	6
BP	GO:0071867	response to monoamine	6/2619	38/18670	0.4461	0.6391	0.4794	MAPK3/SNCA/KCNQ1/PENK/ATP2B4/ATF4	6
BP	GO:0071869	response to catecholamine	6/2619	38/18670	0.4461	0.6391	0.4794	MAPK3/SNCA/KCNQ1/PENK/ATP2B4/ATF4	6
BP	GO:0001974	blood vessel remodeling	7/2619	45/18670	0.4474	0.6406	0.4805	FOXC1/NOL3/AGT/NOS3/RBPJ/AXL/CCR2	7
BP	GO:0071827	plasma lipoprotein particle organization	7/2619	45/18670	0.4474	0.6406	0.4805	LIPC/APOM/APOE/PLA2G7/APOC1/AGT/LPL	7
BP	GO:0090278	negative regulation of peptide hormone secretion	7/2619	45/18670	0.4474	0.6406	0.4805	SFRP1/HADH/CRHBP/MAP4K4/GHSR/PPP3CA/INHBB	7
BP	GO:0032963	collagen metabolic process	17/2619	115/18670	0.448	0.6409	0.4807	MFAP4/GOT1/MRC2/PEPD/BMP4/RCN3/PPARG/F2R/COL15A1/IL6/MMP13/SUCO/MMP12/ADAMTS3/HIF1A/MMP20/LARP6	17
BP	GO:0006301	postreplication repair	8/2619	52/18670	0.4483	0.6409	0.4807	POLD2/RPA1/RPA3/POLD4/UBB/DTL/UBE2L6/RFC2	8
BP	GO:0031529	ruffle organization	8/2619	52/18670	0.4483	0.6409	0.4807	PFN2/SH3YL1/PLEKHA1/CCR7/SNX10/EPS8L2/CYFIP1/LIMA1	8
BP	GO:0048168	regulation of neuronal synaptic plasticity	8/2619	52/18670	0.4483	0.6409	0.4807	SNCA/MCTP1/APOE/KIT/AGT/NCDN/KRAS/CAMK2B	8
BP	GO:0030004	cellular monovalent inorganic cation homeostasis	16/2619	108/18670	0.4483	0.6409	0.4807	SLAMF8/C7/ATP1B1/MAPK3/ATP6V0D1/DMXL2/KCNJ2/TCIRG1/CLN6/AGT/SLC11A1/CA2/ATP6V0E2/RAB20/SLC4A7/NEDD4L	16
BP	GO:0060071	Wnt signaling pathway, planar cell polarity pathway	16/2619	108/18670	0.4483	0.6409	0.4807	SFRP1/PSMB9/AP2M1/WNT11/PLEKHA4/MAGI2/PSMC2/FZD3/PSMB6/PSMC3/PSMD8/PSMB5/PSMD10/FZD6/FZD7/FZD2	16
BP	GO:0007631	feeding behavior	15/2619	101/18670	0.4486	0.6409	0.4807	USP46/UCHL1/NTRK2/RMI1/AGT/HCRT/GHSR/HCRTR2/EN1/NPY1R/AGRP/GAL/CCKAR/GALR3/TH	15
BP	GO:0097006	regulation of plasma lipoprotein particle levels	15/2619	101/18670	0.4486	0.6409	0.4807	LIPC/APOM/LRPAP1/APOE/AP2M1/CNPY2/PLA2G7/HNRNPK/CES3/APOC1/AGT/LIPA/LPL/NPC1/LMF1	15
BP	GO:0006112	energy reserve metabolic process	13/2619	87/18670	0.449	0.6409	0.4807	PPP1R3C/ENPP1/PID1/PGM1/GSK3B/INSR/DYRK2/PYGM/IGF1/MYC/GAA/PASK/SORBS1	13
BP	GO:0045844	positive regulation of striated muscle tissue development	13/2619	87/18670	0.449	0.6409	0.4807	NOTCH1/PIM1/BMP4/ZFPM2/IGF1/TBX5/CCNB1/RBPJ/PIN1/PRKAA1/CREB1/CDK1/ERBB4	13
BP	GO:0048636	positive regulation of muscle organ development	13/2619	87/18670	0.449	0.6409	0.4807	NOTCH1/PIM1/BMP4/ZFPM2/IGF1/TBX5/CCNB1/RBPJ/PIN1/PRKAA1/CREB1/CDK1/ERBB4	13
BP	GO:0015800	acidic amino acid transport	10/2619	66/18670	0.449	0.6409	0.4807	SNCA/PRAF2/SLC7A11/SLC38A2/NTRK2/HRH3/ARL6IP5/VAMP2/SYT1/SLC1A1	10
BP	GO:1904888	cranial skeletal system development	10/2619	66/18670	0.449	0.6409	0.4807	SIX1/NIPBL/SMAD3/BMP4/CEP55/SIX2/IFT140/IRX5/SETD2/TWIST1	10
BP	GO:1905207	regulation of cardiocyte differentiation	10/2619	66/18670	0.449	0.6409	0.4807	EGFR/BMP4/GPER1/RGS4/CTDP1/IGF1/TBX5/RBPJ/PIN1/FZD7	10
BP	GO:0051224	negative regulation of protein transport	28/2619	193/18670	0.455	0.6492	0.487	TNFAIP3/GBP1/SFRP1/CD200/BTN2A2/IL27RA/ANGPT1/SYT11/BARD1/UBE2J1/TNFRSF21/CARD8/APOE/NDFIP1/PTPN22/RAB11FIP1/PTGER4/F2R/HADH/MAP4K4/GHSR/PML/FERMT1/PPP3CA/RHBDF2/INHBB/TLR8/SRGN	28
BP	GO:0051271	negative regulation of cellular component movement	55/2619	384/18670	0.4558	0.6498	0.4874	SLAMF8/ADORA3/SFRP1/PTN/NOTCH1/CD200/IL27RA/IGFBP5/SEMA4D/CXCL13/ABHD6/SEMA4A/SEMA3A/PFN2/MCTP1/CX3CR1/SERPINE1/STC1/ANGPT2/ADA/RAP2C/APOE/LIMCH1/BIN1/SEMA4C/OSBPL8/WNT11/MAGI2/CSNK2B/PPARG/PTGER4/TIE1/KRIT1/CERS2/TRIB1/C5orf30/SEMA3F/TBX5/NBL1/CLASP1/PIN1/HMGB1/AP1AR/SEMA3E/PTPRK/NF2/PADI2/TIMP1/ERBB4/FBLN1/COL3A1/ACTN1/HOXA7/ABHD2/SERPINF1	55
BP	GO:0016482	cytosolic transport	23/2619	158/18670	0.4585	0.6498	0.4874	GAK/MAPK3/VPS13C/PREPL/PIKFYVE/ARL1/STX10/EHD3/VTI1B/VAMP3/SNX2/TRAPPC10/MAGEL2/AP1S1/SORT1/MON2/WDR91/AP1AR/EMP2/HOOK2/ACTR2/AP4M1/DNAJC13	23
BP	GO:0030534	adult behavior	21/2619	144/18670	0.4599	0.6498	0.4874	ZIC1/SNCA/USP46/TMOD1/UCHL1/SLC7A11/PCDH17/BBS4/ADAM22/CHRNA3/CRHBP/GHSR/EN1/EPHA4/CHRNB1/HOXD9/AGRP/ID2/NPC1/SEZ6L/PBX3	21
BP	GO:0072655	establishment of protein localization to mitochondrion	20/2619	137/18670	0.4607	0.6498	0.4874	FIS1/FBXW7/MICALL2/NDUFA13/TIMM10/BAD/PINK1/GZMB/DNAJA1/PPP1R13B/YWHAH/TSPO/TP53BP2/RAC2/ATG13/PRKAA1/SAMM50/MIPEP/UBL5/DDIT3	20
BP	GO:0003231	cardiac ventricle development	19/2619	130/18670	0.4614	0.6498	0.4874	NOTCH1/FOXC1/SMARCD3/RXRA/BMP4/WNT11/MED1/MYL3/FOXF1/RBM15/ZFPM2/NOS3/TBX5/RBPJ/PRDM1/CPE/HIF1A/ID2/FZD2	19
BP	GO:0006493	protein O-linked glycosylation	16/2619	109/18670	0.4638	0.6498	0.4874	GALNT11/GALNT10/SDF2/IL15/EOGT/DPM3/TRAK1/RFNG/GCNT3/ST3GAL2/POFUT1/GALNT3/OGT/MUC5AC/C1GALT1C1/VEGFB	16
BP	GO:0051149	positive regulation of muscle cell differentiation	16/2619	109/18670	0.4638	0.6498	0.4874	CXCL9/CDH2/IL4R/SMARCD3/KIT/BMP4/GPER1/MAML1/MAPK11/IGF1/RBPJ/PIN1/CAMK1/TCF3/TNFSF14/TRIM32	16
BP	GO:0010522	regulation of calcium ion transport into cytosol	15/2619	102/18670	0.4646	0.6498	0.4874	CXCL9/CXCL10/SNCA/SRI/CXCL11/PRNP/GPER1/F2R/PML/XCL1/CD19/P2RX4/CALCR/LIME1/PTK2B	15
BP	GO:0015837	amine transport	15/2619	102/18670	0.4646	0.6498	0.4874	SLC18A2/TACR2/SNCA/SYT11/PINK1/FGF20/HRH3/SYT17/RGS4/CHRNA3/AGT/GHSR/ARL6IP5/SYT1/TH	15
BP	GO:0043044	ATP-dependent chromatin remodeling	13/2619	88/18670	0.4663	0.6498	0.4874	CHD8/ZNHIT1/ARID1A/NASP/PBRM1/HJURP/CENPT/CHD3/PTMA/SMARCA5/HDAC1/SMARCD2/CENPC	13
BP	GO:1901863	positive regulation of muscle tissue development	13/2619	88/18670	0.4663	0.6498	0.4874	NOTCH1/PIM1/BMP4/ZFPM2/IGF1/TBX5/CCNB1/RBPJ/PIN1/PRKAA1/CREB1/CDK1/ERBB4	13
BP	GO:1903321	negative regulation of protein modification by small protein conjugation or removal	13/2619	88/18670	0.4663	0.6498	0.4874	TNFAIP3/DYSF/TRIP12/DNAJA1/ARRB1/TRIM21/TSPO/GLMN/OGT/N4BP1/CRY1/UBR5/FBXO5	13
BP	GO:0099504	synaptic vesicle cycle	28/2619	194/18670	0.4666	0.6498	0.4874	CDH2/SLC18A2/GAK/SNCA/RIMS3/PREPL/SH3GL1/PRKCB/SYT11/FGF14/SYNJ1/PFN2/GSK3B/PCDH17/MAGI2/ROCK1/PLD1/SYT17/ADCY1/VAMP2/CACNB2/CACNA1D/SYT1/CYFIP1/SYN1/RAP1B/NAPA/TH	28
BP	GO:0001510	RNA methylation	12/2619	81/18670	0.4671	0.6498	0.4874	HSD17B10/METTL8/TARBP1/CMTR1/TRMT112/RBM15/DIMT1/TFB2M/TRMT5/MEPCE/NSUN6/TRMT13	12
BP	GO:0021766	hippocampus development	12/2619	81/18670	0.4671	0.6498	0.4874	EZH2/FGF13/GSK3B/LEF1/BBS4/ID4/HDAC1/NF2/UQCRQ/ATP2B4/SMO/EMX2	12
BP	GO:0005977	glycogen metabolic process	11/2619	74/18670	0.468	0.6498	0.4874	PPP1R3C/ENPP1/PGM1/GSK3B/INSR/DYRK2/PYGM/IGF1/GAA/PASK/SORBS1	11
BP	GO:0030104	water homeostasis	11/2619	74/18670	0.468	0.6498	0.4874	AKR1B1/PRKAR2A/UGCG/ADCY1/AQP2/HAS2/ANXA7/ADCY2/FA2H/KRT1/NEDD4L	11
BP	GO:0043534	blood vessel endothelial cell migration	26/2619	180/18670	0.4684	0.6498	0.4874	NOTCH1/PRKD2/FBXW7/ANGPT1/ADAM17/ANGPT2/APOE/CSNK2B/PPARG/GPX1/CD40/HSPB1/PLK2/NOS3/FGF18/KDR/PDGFB/VEGFA/P2RX4/HMGB1/MAP3K3/HIF1A/EMP2/CIB1/STAT5A/PTK2B	26
BP	GO:0070613	regulation of protein processing	26/2619	180/18670	0.4684	0.6498	0.4874	C7/BIRC3/GAS1/PROS1/CLU/SUSD4/PRNP/IFT52/SERPINE1/CARD8/BIRC2/BIRC7/IGLV1-44/NOL3/SPON1/CFI/PHB/CD81/CR1/TMEM59/CD19/C4BPB/CST7/IGLC1/CFP/CD59	26
BP	GO:0003143	embryonic heart tube morphogenesis	10/2619	67/18670	0.4689	0.6498	0.4874	NOTCH1/FOLR1/SMAD3/IFT52/C2CD3/BBS4/MICAL2/TMED2/HIF1A/SMO	10
BP	GO:0032387	negative regulation of intracellular transport	10/2619	67/18670	0.4689	0.6498	0.4874	ANGPT1/BARD1/NUP153/UBE2J1/TPR/CRYAB/FOXF1/FERMT1/RAP1B/IL13RA2	10
BP	GO:0061371	determination of heart left/right asymmetry	10/2619	67/18670	0.4689	0.6498	0.4874	NOTCH1/FOLR1/SMAD3/IFT52/C2CD3/BBS4/MICAL2/TMED2/HIF1A/SMO	10
BP	GO:0010659	cardiac muscle cell apoptotic process	9/2619	60/18670	0.4697	0.6498	0.4874	NUPR1/MAP3K5/JAK2/CFLAR/HSPB6/NOL3/APAF1/AGT/CXCR2	9
BP	GO:0001731	formation of translation preinitiation complex	2/2619	11/18670	0.47	0.6498	0.4874	EIF2S3/EIF2D	2
BP	GO:0001821	histamine secretion	2/2619	11/18670	0.47	0.6498	0.4874	ADA/VAMP7	2
BP	GO:0002328	pro-B cell differentiation	2/2619	11/18670	0.47	0.6498	0.4874	NOTCH1/SOS1	2
BP	GO:0002836	positive regulation of response to tumor cell	2/2619	11/18670	0.47	0.6498	0.4874	CRTAM/FBXO38	2
BP	GO:0002839	positive regulation of immune response to tumor cell	2/2619	11/18670	0.47	0.6498	0.4874	CRTAM/FBXO38	2
BP	GO:0003174	mitral valve development	2/2619	11/18670	0.47	0.6498	0.4874	NOTCH1/TWIST1	2
BP	GO:0006620	posttranslational protein targeting to endoplasmic reticulum membrane	2/2619	11/18670	0.47	0.6498	0.4874	SEC61A2/HSPA5	2
BP	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway	2/2619	11/18670	0.47	0.6498	0.4874	PRMT5/FLNA	2
BP	GO:0008655	pyrimidine-containing compound salvage	2/2619	11/18670	0.47	0.6498	0.4874	TK2/TYMP	2
BP	GO:0009113	purine nucleobase biosynthetic process	2/2619	11/18670	0.47	0.6498	0.4874	ADA/PRPS1	2
BP	GO:0014820	tonic smooth muscle contraction	2/2619	11/18670	0.47	0.6498	0.4874	CD38/AGT	2
BP	GO:0014870	response to muscle inactivity	2/2619	11/18670	0.47	0.6498	0.4874	SGCA/MTMR4	2
BP	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	2/2619	11/18670	0.47	0.6498	0.4874	EXT2/EXTL2	2
BP	GO:0015791	polyol transport	2/2619	11/18670	0.47	0.6498	0.4874	SLC5A3/AQP2	2
BP	GO:0019042	viral latency	2/2619	11/18670	0.47	0.6498	0.4874	BANF1/HMGA1	2
BP	GO:0019852	L-ascorbic acid metabolic process	2/2619	11/18670	0.47	0.6498	0.4874	SLC2A3/CYB5R3	2
BP	GO:0021604	cranial nerve structural organization	2/2619	11/18670	0.47	0.6498	0.4874	SEMA3A/SEMA3F	2
BP	GO:0021670	lateral ventricle development	2/2619	11/18670	0.47	0.6498	0.4874	TSKU/MYH10	2
BP	GO:0030422	production of siRNA involved in RNA interference	2/2619	11/18670	0.47	0.6498	0.4874	PRKRA/TSN	2
BP	GO:0031442	positive regulation of mRNA 3'-end processing	2/2619	11/18670	0.47	0.6498	0.4874	CCNB1/NCBP2	2
BP	GO:0031987	locomotion involved in locomotory behavior	2/2619	11/18670	0.47	0.6498	0.4874	CLN6/GHSR	2
BP	GO:0032276	regulation of gonadotropin secretion	2/2619	11/18670	0.47	0.6498	0.4874	TACR2/INHBB	2
BP	GO:0032306	regulation of prostaglandin secretion	2/2619	11/18670	0.47	0.6498	0.4874	TNFRSF11A/P2RX4	2
BP	GO:0032351	negative regulation of hormone metabolic process	2/2619	11/18670	0.47	0.6498	0.4874	NFKB1/AKR1C3	2
BP	GO:0032377	regulation of intracellular lipid transport	2/2619	11/18670	0.47	0.6498	0.4874	SCP2/ABCA2	2
BP	GO:0032380	regulation of intracellular sterol transport	2/2619	11/18670	0.47	0.6498	0.4874	SCP2/ABCA2	2
BP	GO:0032383	regulation of intracellular cholesterol transport	2/2619	11/18670	0.47	0.6498	0.4874	SCP2/ABCA2	2
BP	GO:0032490	detection of molecule of bacterial origin	2/2619	11/18670	0.47	0.6498	0.4874	TREM2/NOD2	2
BP	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway	2/2619	11/18670	0.47	0.6498	0.4874	AR/MED1	2
BP	GO:0033235	positive regulation of protein sumoylation	2/2619	11/18670	0.47	0.6498	0.4874	UBE2I/TOLLIP	2
BP	GO:0033860	regulation of NAD(P)H oxidase activity	2/2619	11/18670	0.47	0.6498	0.4874	SLAMF8/AGT	2
BP	GO:0034115	negative regulation of heterotypic cell-cell adhesion	2/2619	11/18670	0.47	0.6498	0.4874	MAPK7/IL1RN	2
BP	GO:0035457	cellular response to interferon-alpha	2/2619	11/18670	0.47	0.6498	0.4874	TPR/AXL	2
BP	GO:0035739	CD4-positive, alpha-beta T cell proliferation	2/2619	11/18670	0.47	0.6498	0.4874	CD81/XCL1	2
BP	GO:0035766	cell chemotaxis to fibroblast growth factor	2/2619	11/18670	0.47	0.6498	0.4874	CXCL13/FGF18	2
BP	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity	2/2619	11/18670	0.47	0.6498	0.4874	MICB/ULBP2	2
BP	GO:0043097	pyrimidine nucleoside salvage	2/2619	11/18670	0.47	0.6498	0.4874	TK2/TYMP	2
BP	GO:0043129	surfactant homeostasis	2/2619	11/18670	0.47	0.6498	0.4874	RCN3/VEGFA	2
BP	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress	2/2619	11/18670	0.47	0.6498	0.4874	HIF1A/ATF4	2
BP	GO:0045628	regulation of T-helper 2 cell differentiation	2/2619	11/18670	0.47	0.6498	0.4874	IL4R/TNFSF4	2
BP	GO:0045835	negative regulation of meiotic nuclear division	2/2619	11/18670	0.47	0.6498	0.4874	RAD1/FBXO5	2
BP	GO:0046007	negative regulation of activated T cell proliferation	2/2619	11/18670	0.47	0.6498	0.4874	BTN2A2/PRNP	2
BP	GO:0046185	aldehyde catabolic process	2/2619	11/18670	0.47	0.6498	0.4874	ESD/ALDH3B1	2
BP	GO:0046439	L-cysteine metabolic process	2/2619	11/18670	0.47	0.6498	0.4874	CBS/AHCY	2
BP	GO:0046512	sphingosine biosynthetic process	2/2619	11/18670	0.47	0.6498	0.4874	SPHK1/ASAH1	2
BP	GO:0046689	response to mercury ion	2/2619	11/18670	0.47	0.6498	0.4874	BSG/AQP2	2
BP	GO:0048548	regulation of pinocytosis	2/2619	11/18670	0.47	0.6498	0.4874	NR1H2/AXL	2
BP	GO:0051013	microtubule severing	2/2619	11/18670	0.47	0.6498	0.4874	SPAST/KATNB1	2
BP	GO:0051561	positive regulation of mitochondrial calcium ion concentration	2/2619	11/18670	0.47	0.6498	0.4874	FIS1/MICU1	2
BP	GO:0051573	negative regulation of histone H3-K9 methylation	2/2619	11/18670	0.47	0.6498	0.4874	DNMT1/KDM3A	2
BP	GO:0051791	medium-chain fatty acid metabolic process	2/2619	11/18670	0.47	0.6498	0.4874	ACADM/ABHD2	2
BP	GO:0051974	negative regulation of telomerase activity	2/2619	11/18670	0.47	0.6498	0.4874	PARP3/PPARG	2
BP	GO:0055091	phospholipid homeostasis	2/2619	11/18670	0.47	0.6498	0.4874	RCN3/FABP3	2
BP	GO:0060159	regulation of dopamine receptor signaling pathway	2/2619	11/18670	0.47	0.6498	0.4874	PRMT5/RGS4	2
BP	GO:0060174	limb bud formation	2/2619	11/18670	0.47	0.6498	0.4874	SOX9/ZNF219	2
BP	GO:0060379	cardiac muscle cell myoblast differentiation	2/2619	11/18670	0.47	0.6498	0.4874	NOTCH1/RBPJ	2
BP	GO:0060856	establishment of blood-brain barrier	2/2619	11/18670	0.47	0.6498	0.4874	MXRA8/LSR	2
BP	GO:0061365	positive regulation of triglyceride lipase activity	2/2619	11/18670	0.47	0.6498	0.4874	NR1H2/LMF1	2
BP	GO:0070587	regulation of cell-cell adhesion involved in gastrulation	2/2619	11/18670	0.47	0.6498	0.4874	MAPK7/IL1RN	2
BP	GO:0070673	response to interleukin-18	2/2619	11/18670	0.47	0.6498	0.4874	RIPK2/PDGFB	2
BP	GO:0071372	cellular response to follicle-stimulating hormone stimulus	2/2619	11/18670	0.47	0.6498	0.4874	NOTCH1/EFNA5	2
BP	GO:0071803	positive regulation of podosome assembly	2/2619	11/18670	0.47	0.6498	0.4874	LCP1/ASAP1	2
BP	GO:0072173	metanephric tubule morphogenesis	2/2619	11/18670	0.47	0.6498	0.4874	SOX9/CXCR2	2
BP	GO:0072537	fibroblast activation	2/2619	11/18670	0.47	0.6498	0.4874	RPS6KA1/IL17RA	2
BP	GO:0072584	caveolin-mediated endocytosis	2/2619	11/18670	0.47	0.6498	0.4874	MAPK3/NEDD4L	2
BP	GO:0072683	T cell extravasation	2/2619	11/18670	0.47	0.6498	0.4874	IL27RA/CCR2	2
BP	GO:0086016	AV node cell action potential	2/2619	11/18670	0.47	0.6498	0.4874	CACNB2/CXADR	2
BP	GO:0086023	adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process	2/2619	11/18670	0.47	0.6498	0.4874	ATP2B4/AKAP13	2
BP	GO:0086027	AV node cell to bundle of His cell signaling	2/2619	11/18670	0.47	0.6498	0.4874	CACNB2/CXADR	2
BP	GO:0097499	protein localization to non-motile cilium	2/2619	11/18670	0.47	0.6498	0.4874	BBS4/ZDHHC3	2
BP	GO:1900102	negative regulation of endoplasmic reticulum unfolded protein response	2/2619	11/18670	0.47	0.6498	0.4874	NCK2/HSPA5	2
BP	GO:1900115	extracellular regulation of signal transduction	2/2619	11/18670	0.47	0.6498	0.4874	LRPAP1/NBL1	2
BP	GO:1900116	extracellular negative regulation of signal transduction	2/2619	11/18670	0.47	0.6498	0.4874	LRPAP1/NBL1	2
BP	GO:1901569	fatty acid derivative catabolic process	2/2619	11/18670	0.47	0.6498	0.4874	OXCT1/ACAT1	2
BP	GO:1901678	iron coordination entity transport	2/2619	11/18670	0.47	0.6498	0.4874	SLC22A17/SLC48A1	2
BP	GO:1903299	regulation of hexokinase activity	2/2619	11/18670	0.47	0.6498	0.4874	BAD/RANBP2	2
BP	GO:1904396	regulation of neuromuscular junction development	2/2619	11/18670	0.47	0.6498	0.4874	SIX1/PTN	2
BP	GO:1904847	regulation of cell chemotaxis to fibroblast growth factor	2/2619	11/18670	0.47	0.6498	0.4874	CXCL13/FGF18	2
BP	GO:1905214	regulation of RNA binding	2/2619	11/18670	0.47	0.6498	0.4874	LARP6/CDK9	2
BP	GO:1905245	regulation of aspartic-type peptidase activity	2/2619	11/18670	0.47	0.6498	0.4874	BIN1/EPHA4	2
BP	GO:1905383	protein localization to presynapse	2/2619	11/18670	0.47	0.6498	0.4874	HSPB1/KIF5C	2
BP	GO:2000318	positive regulation of T-helper 17 type immune response	2/2619	11/18670	0.47	0.6498	0.4874	MALT1/PRKCQ	2
BP	GO:2000392	regulation of lamellipodium morphogenesis	2/2619	11/18670	0.47	0.6498	0.4874	CD44/ARHGEF7	2
BP	GO:2000561	regulation of CD4-positive, alpha-beta T cell proliferation	2/2619	11/18670	0.47	0.6498	0.4874	CD81/XCL1	2
BP	GO:2001204	regulation of osteoclast development	2/2619	11/18670	0.47	0.6498	0.4874	FBXW7/TYROBP	2
BP	GO:0006376	mRNA splice site selection	8/2619	53/18670	0.4706	0.6498	0.4874	SETX/CELF2/NOL3/CELF1/SFSWAP/PTBP2/YTHDC1/LUC7L	8
BP	GO:0007632	visual behavior	8/2619	53/18670	0.4706	0.6498	0.4874	SLC7A11/B4GALT2/DYNLRB1/KIT/DEAF1/HIF1A/CREB1/KRAS	8
BP	GO:0030195	negative regulation of blood coagulation	8/2619	53/18670	0.4706	0.6498	0.4874	PROS1/SERPINE1/APOE/TFPI/NOS3/PDGFB/KRT1/SH2B3	8
BP	GO:0036297	interstrand cross-link repair	8/2619	53/18670	0.4706	0.6498	0.4874	DCLRE1C/ERCC1/RFWD3/ATR/FANCI/RPA1/RPA3/UBB	8
BP	GO:0019731	antibacterial humoral response	7/2619	46/18670	0.4714	0.6498	0.4874	SLPI/HLA-E/IGHM/ELANE/DEFA6/CTSG/DEFA5	7
BP	GO:0022602	ovulation cycle process	7/2619	46/18670	0.4714	0.6498	0.4874	PLEKHA1/ARRB1/NOS3/EREG/GDF9/SGPL1/HSPA5	7
BP	GO:0051339	regulation of lyase activity	7/2619	46/18670	0.4714	0.6498	0.4874	TIMP2/GUCA1A/NOS3/AKAP9/CACNA1D/GALR3/CCR2	7
BP	GO:0002251	organ or tissue specific immune response	6/2619	39/18670	0.4722	0.6498	0.4874	GCNT3/IL6/XCL1/DEFA6/IL6R/DEFA5	6
BP	GO:0010761	fibroblast migration	6/2619	39/18670	0.4722	0.6498	0.4874	PRR5L/ARHGEF7/C5orf30/PML/TNS1/SGPL1	6
BP	GO:0042417	dopamine metabolic process	6/2619	39/18670	0.4722	0.6498	0.4874	GCH1/SNCA/COMT/MOXD1/SNCAIP/TH	6
BP	GO:0051180	vitamin transport	6/2619	39/18670	0.4722	0.6498	0.4874	FOLR1/CD320/SLC2A6/FOLR2/ABCC1/LMBRD1	6
BP	GO:0055090	acylglycerol homeostasis	6/2619	39/18670	0.4722	0.6498	0.4874	LIPC/RORA/MED13/APOE/LPL/XBP1	6
BP	GO:0070328	triglyceride homeostasis	6/2619	39/18670	0.4722	0.6498	0.4874	LIPC/RORA/MED13/APOE/LPL/XBP1	6
BP	GO:1901998	toxin transport	6/2619	39/18670	0.4722	0.6498	0.4874	RAB40B/DNAJA1/ARID1A/LRP5/CCT6B/HSPA5	6
BP	GO:0002902	regulation of B cell apoptotic process	3/2619	18/18670	0.4727	0.6498	0.4874	ADA/AURKB/BCL10	3
BP	GO:0003414	chondrocyte morphogenesis involved in endochondral bone morphogenesis	3/2619	18/18670	0.4727	0.6498	0.4874	SCARA3/COL6A3/MBL2	3
BP	GO:0003429	growth plate cartilage chondrocyte morphogenesis	3/2619	18/18670	0.4727	0.6498	0.4874	SCARA3/COL6A3/MBL2	3
BP	GO:0006743	ubiquinone metabolic process	3/2619	18/18670	0.4727	0.6498	0.4874	COQ6/COQ9/COQ2	3
BP	GO:0007194	negative regulation of adenylate cyclase activity	3/2619	18/18670	0.4727	0.6498	0.4874	AKAP9/GALR3/CCR2	3
BP	GO:0007250	activation of NF-kappaB-inducing kinase activity	3/2619	18/18670	0.4727	0.6498	0.4874	MALT1/COPS8/CARD14	3
BP	GO:0009048	dosage compensation by inactivation of X chromosome	3/2619	18/18670	0.4727	0.6498	0.4874	SMCHD1/RBM15/YTHDC1	3
BP	GO:0009312	oligosaccharide biosynthetic process	3/2619	18/18670	0.4727	0.6498	0.4874	B3GALNT1/ST3GAL2/FUT8	3
BP	GO:0010612	regulation of cardiac muscle adaptation	3/2619	18/18670	0.4727	0.6498	0.4874	SMAD3/PPP3CA/ATP2B4	3
BP	GO:0010713	negative regulation of collagen metabolic process	3/2619	18/18670	0.4727	0.6498	0.4874	GOT1/PPARG/IL6	3
BP	GO:0010878	cholesterol storage	3/2619	18/18670	0.4727	0.6498	0.4874	PPARG/NR1H2/LPL	3
BP	GO:0032693	negative regulation of interleukin-10 production	3/2619	18/18670	0.4727	0.6498	0.4874	TNFRSF21/IDO1/TYROBP	3
BP	GO:0034199	activation of protein kinase A activity	3/2619	18/18670	0.4727	0.6498	0.4874	PRKAR2A/ADCY1/ADCY2	3
BP	GO:0035994	response to muscle stretch	3/2619	18/18670	0.4727	0.6498	0.4874	NFKBIA/NFKB1/RAF1	3
BP	GO:0043011	myeloid dendritic cell differentiation	3/2619	18/18670	0.4727	0.6498	0.4874	RELB/RBPJ/BATF	3
BP	GO:0045056	transcytosis	3/2619	18/18670	0.4727	0.6498	0.4874	FCGRT/LRPAP1/RAB11B	3
BP	GO:0060192	negative regulation of lipase activity	3/2619	18/18670	0.4727	0.6498	0.4874	APOC1/SORT1/PLA2R1	3
BP	GO:0071371	cellular response to gonadotropin stimulus	3/2619	18/18670	0.4727	0.6498	0.4874	NOTCH1/CCNA2/EFNA5	3
BP	GO:0072311	glomerular epithelial cell differentiation	3/2619	18/18670	0.4727	0.6498	0.4874	BMP4/MAGI2/PODXL	3
BP	GO:0090171	chondrocyte morphogenesis	3/2619	18/18670	0.4727	0.6498	0.4874	SCARA3/COL6A3/MBL2	3
BP	GO:0090196	regulation of chemokine secretion	3/2619	18/18670	0.4727	0.6498	0.4874	IL4R/POSTN/LPL	3
BP	GO:0150078	positive regulation of neuroinflammatory response	3/2619	18/18670	0.4727	0.6498	0.4874	NUPR1/TREM2/IL6	3
BP	GO:1903242	regulation of cardiac muscle hypertrophy in response to stress	3/2619	18/18670	0.4727	0.6498	0.4874	SMAD3/PPP3CA/ATP2B4	3
BP	GO:1904872	regulation of telomerase RNA localization to Cajal body	3/2619	18/18670	0.4727	0.6498	0.4874	NHP2/DCP2/RUVBL2	3
BP	GO:1905276	regulation of epithelial tube formation	3/2619	18/18670	0.4727	0.6498	0.4874	SIX1/SFRP1/FZD2	3
BP	GO:2000479	regulation of cAMP-dependent protein kinase activity	3/2619	18/18670	0.4727	0.6498	0.4874	PRKAR2A/ADRB2/ATP2B4	3
BP	GO:2000647	negative regulation of stem cell proliferation	3/2619	18/18670	0.4727	0.6498	0.4874	PTN/FERMT1/FBLN1	3
BP	GO:0003338	metanephros morphogenesis	5/2619	32/18670	0.4728	0.6498	0.4874	STAT1/SOX9/BMP4/SIX2/SMO	5
BP	GO:0008210	estrogen metabolic process	5/2619	32/18670	0.4728	0.6498	0.4874	COMT/HSD17B1/PLEKHA1/HSD17B14/SGPL1	5
BP	GO:0046949	fatty-acyl-CoA biosynthetic process	5/2619	32/18670	0.4728	0.6498	0.4874	TECR/SLC25A1/ACSL5/ACAT1/SCD5	5
BP	GO:0050779	RNA destabilization	5/2619	32/18670	0.4728	0.6498	0.4874	TNFRSF1B/FTO/ROCK1/ZFP36L2/HNRNPD	5
BP	GO:0060317	cardiac epithelial to mesenchymal transition	5/2619	32/18670	0.4728	0.6498	0.4874	NOTCH1/TMEM100/RBPJ/HAS2/TWIST1	5
BP	GO:0070207	protein homotrimerization	5/2619	32/18670	0.4728	0.6498	0.4874	ALOX5AP/SIGMAR1/HLA-G/ATXN10/CD247	5
BP	GO:0007214	gamma-aminobutyric acid signaling pathway	4/2619	25/18670	0.4731	0.6498	0.4874	GABRB1/GABRA4/GABBR1/ATF4	4
BP	GO:0008211	glucocorticoid metabolic process	4/2619	25/18670	0.4731	0.6498	0.4874	HSD11B2/CYP11A1/YWHAH/GAL	4
BP	GO:0014829	vascular smooth muscle contraction	4/2619	25/18670	0.4731	0.6498	0.4874	CD38/AGT/COMP/ATP2B1	4
BP	GO:0021952	central nervous system projection neuron axonogenesis	4/2619	25/18670	0.4731	0.6498	0.4874	SCN1B/MYCBP2/EPHA4/TSKU	4
BP	GO:0034035	purine ribonucleoside bisphosphate metabolic process	4/2619	25/18670	0.4731	0.6498	0.4874	ENPP1/TPST1/SULT1A2/PAPSS1	4
BP	GO:0034110	regulation of homotypic cell-cell adhesion	4/2619	25/18670	0.4731	0.6498	0.4874	CCL5/ANK3/PRKCQ/SH2B3	4
BP	GO:0035459	cargo loading into vesicle	4/2619	25/18670	0.4731	0.6498	0.4874	SEC24A/SEC13/TMED2/TMED10	4
BP	GO:0045724	positive regulation of cilium assembly	4/2619	25/18670	0.4731	0.6498	0.4874	CEP135/MNS1/BBS4/ARHGAP35	4
BP	GO:0046755	viral budding	4/2619	25/18670	0.4731	0.6498	0.4874	VPS37C/CHMP6/CHMP2A/CHMP1B	4
BP	GO:0051156	glucose 6-phosphate metabolic process	4/2619	25/18670	0.4731	0.6498	0.4874	RBKS/G6PC3/NFE2L1/RPE	4
BP	GO:0060444	branching involved in mammary gland duct morphogenesis	4/2619	25/18670	0.4731	0.6498	0.4874	AR/MED1/LRP5/PML	4
BP	GO:0060571	morphogenesis of an epithelial fold	4/2619	25/18670	0.4731	0.6498	0.4874	AR/EGFR/BMP4/HIF1A	4
BP	GO:0061050	regulation of cell growth involved in cardiac muscle cell development	4/2619	25/18670	0.4731	0.6498	0.4874	RGS4/CTDP1/IGF1/PIN1	4
BP	GO:0070129	regulation of mitochondrial translation	4/2619	25/18670	0.4731	0.6498	0.4874	UQCC1/RMND1/COA3/NGRN	4
BP	GO:0070199	establishment of protein localization to chromosome	4/2619	25/18670	0.4731	0.6498	0.4874	NIPBL/BRCA2/RUVBL2/NABP2	4
BP	GO:1904385	cellular response to angiotensin	4/2619	25/18670	0.4731	0.6498	0.4874	ROCK1/NFKB1/AGT/CA2	4
BP	GO:1905809	negative regulation of synapse organization	4/2619	25/18670	0.4731	0.6498	0.4874	PTN/LILRB2/PRNP/APOE	4
BP	GO:0043666	regulation of phosphoprotein phosphatase activity	17/2619	117/18670	0.478	0.6564	0.4923	PTN/JAK2/PTPRC/GSK3B/PPP6R3/SET/MAGI2/ROCK1/SHOC2/PPP4R1/PPP1R16B/PPP1R12A/ANKLE2/PHACTR4/ENSA/LGALS3/STYXL1	17
BP	GO:0090175	regulation of establishment of planar polarity	16/2619	110/18670	0.4793	0.658	0.4935	SFRP1/PSMB9/AP2M1/WNT11/PLEKHA4/MAGI2/PSMC2/FZD3/PSMB6/PSMC3/PSMD8/PSMB5/PSMD10/FZD6/FZD7/FZD2	16
BP	GO:0006941	striated muscle contraction	25/2619	174/18670	0.4817	0.6611	0.4958	SCN1B/ATP1B1/SNTA1/SRI/KCNQ1/STC1/BIN1/EHD3/KCNJ2/MYL3/CXCR4/TAZ/CHUK/P2RX4/MYL4/CHRNB1/CACNB2/KCNJ8/KCNN2/GAA/CACNA1D/FLNA/NEDD4L/VEGFB/PIK3CA	25
BP	GO:0019217	regulation of fatty acid metabolic process	14/2619	96/18670	0.482	0.6613	0.496	PDK2/SNCA/ERLIN2/GSTZ1/PPARG/APOC1/WDTC1/NR1H2/GHSR/PDK1/NFE2L1/EIF6/FABP3/TWIST1	14
BP	GO:0030219	megakaryocyte differentiation	14/2619	96/18670	0.482	0.6613	0.496	KIT/MED1/RBM15/ZNF16/SCIN/PRKCQ/ABI1/AGO3/HDAC1/CIB1/KAT2B/EIF6/EP300/SH2B3	14
BP	GO:0007519	skeletal muscle tissue development	23/2619	160/18670	0.4841	0.6641	0.4981	PITX1/SIX1/NUPR1/NOTCH1/MYL6B/CFLAR/ATF3/MYOM2/GPX1/TAZ/CCNT2/MAFF/EGR1/PPP3CA/HOXD9/PRKAA1/HLF/SAP30/EP300/SMO/GTF3C5/TWIST1/NR1D2	23
BP	GO:0055117	regulation of cardiac muscle contraction	12/2619	82/18670	0.4851	0.6652	0.4989	ATP1B1/SRI/KCNQ1/FGF13/STC1/BIN1/EHD3/KCNJ2/P2RX4/AKAP9/RANGRF/FLNA	12
CC	GO:0031983	vesicle lumen	84/2684	339/19717	2.054e-08	1.431e-05	1.101e-05	FUCA1/MAGED2/CRISPLD2/GUSB/PROS1/CLU/CTSW/SLPI/RAB27A/SERPINA3/PCSK1/SERPINA1/HGF/IMPDH2/CTSA/DNASE1L1/HSPH1/EGFR/EGF/TIMP2/SERPINE1/ADA/APOE/CFD/PRDX6/ITIH4/C6orf120/RNASE2/PENK/VTI1B/CSNK2B/PSMC2/ROCK1/FGR/TOLLIP/F8/GGH/CAT/ELANE/PNP/NFKB1/APAF1/QPCT/FTL/IGF1/GNLY/PSMC3/HSPA6/GM2A/PDGFB/VEGFA/SERPINA4/DYNC1H1/HMGB1/COMMD9/KPNB1/PPIE/NEU1/HBB/DNAJC3/CRISP3/PADI2/CYB5R3/GSDMD/ERP44/GCA/CTSG/DEFA5/ALDOC/FCN1/S100A12/GTPBP2/TIMP1/SCCPDH/CEP290/CYFIP1/MVP/ACTN1/ACTR2/AMPD3/CFP/ARSB/VEGFB/SRGN	84
CC	GO:0060205	cytoplasmic vesicle lumen	83/2684	338/19717	3.83e-08	1.431e-05	1.101e-05	FUCA1/MAGED2/CRISPLD2/GUSB/PROS1/CLU/CTSW/SLPI/RAB27A/SERPINA3/PCSK1/SERPINA1/HGF/IMPDH2/CTSA/DNASE1L1/HSPH1/EGF/TIMP2/SERPINE1/ADA/APOE/CFD/PRDX6/ITIH4/C6orf120/RNASE2/PENK/VTI1B/CSNK2B/PSMC2/ROCK1/FGR/TOLLIP/F8/GGH/CAT/ELANE/PNP/NFKB1/APAF1/QPCT/FTL/IGF1/GNLY/PSMC3/HSPA6/GM2A/PDGFB/VEGFA/SERPINA4/DYNC1H1/HMGB1/COMMD9/KPNB1/PPIE/NEU1/HBB/DNAJC3/CRISP3/PADI2/CYB5R3/GSDMD/ERP44/GCA/CTSG/DEFA5/ALDOC/FCN1/S100A12/GTPBP2/TIMP1/SCCPDH/CEP290/CYFIP1/MVP/ACTN1/ACTR2/AMPD3/CFP/ARSB/VEGFB/SRGN	83
CC	GO:0005635	nuclear envelope	104/2684	464/19717	1.237e-07	2.904e-05	2.234e-05	GCH1/LTC4S/GCHFR/IL15RA/CETN2/NELL1/MAPK3/BNIP1/LBR/ATP2A3/SNCA/ALOX5AP/SIGMAR1/CLMN/SMAD3/OSBPL3/ATRAID/NUP160/TNKS2/SYNE2/GABRB1/NUP153/EGFR/NDUFB4/PRNP/AGPAT5/NPAP1/PUM2/SLC22A18/CERS6/INSR/CDK4/DNAJB14/TPR/RAB40B/BIN1/MGST3/DNAJC1/UBE2I/OSBPL8/MTMR6/NUP50/TNMD/MNS1/LMNB1/SCRN1/CERS4/SEC13/RANBP2/GPER1/UBXN4/NXF1/DPY19L2P2/GPX4/TOR1AIP1/CLCA2/PLA2G4C/CERS2/BANF1/RBM15/PCM1/ATF6/LRMP/CHMP2A/RAC2/SNUPN/PTGDS/NUP210/SORT1/DUSP2/MTDH/CUEDC2/P2RX4/DTL/DHCR7/KPNB1/PGRMC2/ATP11B/NUP43/SPAST/NDC1/YBX1/ABCF1/ANXA7/TXNL4A/PHF11/SEPHS1/KPNA1/TYRO3/CCND2/MVP/TMPO/KPNA3/PHLPP1/HOXA7/NPC1/UNC50/VAPA/LPIN1/NUP98/CENPF/TMEM97/NUP62/RTCB	104
CC	GO:0034774	secretory granule lumen	78/2684	321/19717	1.555e-07	2.904e-05	2.234e-05	FUCA1/MAGED2/CRISPLD2/GUSB/PROS1/CLU/CTSW/SLPI/RAB27A/SERPINA3/PCSK1/SERPINA1/HGF/IMPDH2/CTSA/DNASE1L1/EGF/TIMP2/SERPINE1/CFD/PRDX6/ITIH4/C6orf120/RNASE2/PENK/VTI1B/CSNK2B/PSMC2/ROCK1/FGR/TOLLIP/F8/GGH/CAT/ELANE/PNP/NFKB1/APAF1/QPCT/FTL/IGF1/PSMC3/HSPA6/GM2A/PDGFB/VEGFA/SERPINA4/DYNC1H1/HMGB1/COMMD9/KPNB1/PPIE/NEU1/DNAJC3/CRISP3/PADI2/CYB5R3/GSDMD/ERP44/GCA/CTSG/DEFA5/ALDOC/FCN1/S100A12/GTPBP2/TIMP1/SCCPDH/CEP290/CYFIP1/MVP/ACTN1/ACTR2/AMPD3/CFP/ARSB/VEGFB/SRGN	78
CC	GO:0005819	spindle	82/2684	347/19717	2.677e-07	3.999e-05	3.077e-05	CDC25B/RMDN3/BEX4/CDC7/TOPBP1/CEP350/ECT2/TUBG2/ARL3/NDE1/ASPM/HAUS3/ATM/DLGAP5/ACOT13/KIF2A/TPX2/TADA3/RACGAP1/NEDD9/DCTN3/TPR/HAUS2/DDX11/MAPRE3/BUB1B/MMS19/NUSAP1/SPAG5/ARHGEF2/MAP7D3/CDC14A/CDCA8/KNTC1/KIF18B/HSPB1/PRC1/EML1/PLK2/CENPE/KIF11/CTDP1/LRMP/CCNB1/DYNC1I1/SHCBP1/KIF4A/CLASP1/KIF15/CDC20/NUBP2/TUBGCP5/ARL2BP/AURKB/PARP4/BIRC5/IQCB1/AGBL5/MZT2B/NCOR1/SPAST/KATNB1/ALMS1/SMC1A/YEATS2/ERCC2/CYLD/CTTN/IKBKG/TACC3/CDK1/MAPRE2/EML4/CEP63/HSPA2/SPICE1/KIF20A/TUBGCP2/MYH10/CENPF/NUP62/FBXO5	82
CC	GO:0061695	transferase complex, transferring phosphorus-containing groups	65/2684	259/19717	4.855e-07	6.044e-05	4.65e-05	SIK1/SOCS6/MAP3K5/ERCC1/PRKAR2A/CCNA2/POLD2/WDR61/POLR2J/POLR2I/POLR2L/POLR3C/DNA2/POLR2E/POLR2F/UVRAG/TADA3/CKS1B/INSR/CDK4/SOCS1/PRKAG1/PRKAB1/MMS19/PIK3C2B/SETD5/POLD4/POLR2C/CKS2/POLR1B/TAF10/PFKM/PEX2/CCNT2/POLG/CCNB2/GTF2A2/CHUK/PIK3CB/TRRAP/CCNB1/CCNH/PIK3R5/TAF9B/POLR2G/TAF7/ATG13/CCNK/ERCC2/PRKAA1/PIK3CD/IKBKG/CDK1/CCND2/CDKN1A/MNAT1/POLR1C/PRPS1/PIK3C2G/GTF2H3/CDK9/PRPS2/CISH/PIK3CA/SORBS1	65
CC	GO:0098803	respiratory chain complex	29/2684	85/19717	1.25e-06	0.0001334	0.0001026	NDUFC1/SDHC/NDUFA13/NDUFS4/NDUFA4L2/NDUFB4/NDUFA4/UQCR10/NDUFA8/CYC1/COX8A/NDUFA2/COX6A1/NDUFB6/NDUFB7/SDHD/NDUFB2/NDUFA6/NDUFA10/COA3/NDUFB11/NDUFB8/NDUFA3/UQCRQ/NDUFS3/NDUFS7/NDUFS6/NDUFA1/UQCRC1	29
CC	GO:0030667	secretory granule membrane	70/2684	298/19717	2.449e-06	0.0002287	0.0001759	SLC2A3/CYB5R1/NBEAL2/IQGAP2/TNFRSF1B/RPH3AL/SNCA/SRI/LAMP3/STK10/RAB27A/LILRB2/OLR1/PTPRC/CD38/SERPINA5/ABCC4/ITGAX/ITGAL/BSG/RAP2C/APLP2/ABCA3/PECAM1/SERPINB6/RHOF/TMEM30A/PGRMC1/PLD1/MOXD1/TCIRG1/CD93/CD44/CMTM6/CR1/ITPR2/CD63/PTPRN2/LRMP/VAMP7/RND2/TYROBP/ATP8A1/SLC11A1/PLA1A/SLC2A5/CPE/CXCR2/LAMTOR2/TMED2/DDOST/VAMP2/ATP11B/CD58/EXOC3/TMED10/GAA/ANXA7/VNN1/LGALS3/SYT1/UBR4/ANPEP/RAP1B/VAPA/PSAP/ALDH3B1/DNAJC13/NRAS/CD59	70
CC	GO:0005746	mitochondrial respiratory chain	29/2684	88/19717	2.788e-06	0.0002314	0.000178	COX7A1/NDUFC1/SDHC/NDUFA13/NDUFS4/NDUFA4L2/NDUFB4/NDUFA4/UQCR10/NDUFA8/CYC1/NDUFA2/COX6A1/NDUFB6/NDUFB7/SDHD/NDUFB2/NDUFA6/NDUFA10/COA3/NDUFB11/NDUFB8/NDUFA3/UQCRQ/NDUFS3/NDUFS7/NDUFS6/NDUFA1/UQCRC1	29
CC	GO:0045171	intercellular bridge	22/2684	59/19717	4.51e-06	0.0003369	0.0002592	MICAL1/SETX/CDC7/HAUS3/TPX2/THOC1/SNRNP25/AAMP/GSTM4/CEP55/CDCA8/PRKCI/GSTM5/KIF4A/PKNOX2/GSTM3/IQCB1/AGBL5/DNAJC8/CENPC/KIF20A/TRIM45	22
CC	GO:0044438	microbody part	31/2684	100/19717	5.454e-06	0.0003395	0.0002612	FIS1/ECI2/PEX10/EPHX2/ACOX2/PEX19/DECR2/IMPDH2/DDO/TTC1/PHYH/IDE/HMGCL/PXMP2/ECH1/PEX7/PEX11A/CAT/PEX2/SCP2/GRHPR/ALDH3A2/PEX12/PEX14/ACOX1/AGPS/ACOT8/MPV17/FAR2/CRAT/PXMP4	31
CC	GO:0044439	peroxisomal part	31/2684	100/19717	5.454e-06	0.0003395	0.0002612	FIS1/ECI2/PEX10/EPHX2/ACOX2/PEX19/DECR2/IMPDH2/DDO/TTC1/PHYH/IDE/HMGCL/PXMP2/ECH1/PEX7/PEX11A/CAT/PEX2/SCP2/GRHPR/ALDH3A2/PEX12/PEX14/ACOX1/AGPS/ACOT8/MPV17/FAR2/CRAT/PXMP4	31
CC	GO:0030496	midbody	45/2684	173/19717	9.929e-06	0.0005705	0.000439	MICAL1/ECT2/ZNF330/CNTRL/ARL3/ASPM/LAP3/USP3/UVRAG/RACGAP1/DCTN3/RALA/DDX11/EXOC7/MAPRE3/SPAG5/CEP55/CDCA8/PRC1/CENPE/CTDP1/PIK3CB/EXOC2/SHCBP1/KIF4A/ARL2BP/AURKB/PIN1/USP8/BIRC5/AGBL5/EXOC3/SPAST/KATNB1/CYLD/CHMP1B/CDK1/CENPC/SCCPDH/KIF20A/EXOC1/HSPA5/MYH10/CENPF/NUP62	45
CC	GO:0016605	PML body	30/2684	99/19717	1.269e-05	0.0006393	0.0004919	SMC6/TOPBP1/ELF4/NBN/RFWD3/ATR/CHEK2/TDG/RPA1/CHFR/MAPK7/UBE2I/RNF111/ZNF451/SMC5/ISG20/ZMYM2/RPAIN/DAXX/PML/ATRX/HMBOX1/SATB1/CASP8AP2/KAT6A/MKNK2/TCF7L2/N4BP1/UBN1/CDK9	30
CC	GO:0005747	mitochondrial respiratory chain complex I	19/2684	50/19717	1.455e-05	0.0006393	0.0004919	NDUFC1/NDUFA13/NDUFS4/NDUFB4/NDUFA4/NDUFA8/NDUFA2/NDUFB6/NDUFB7/NDUFB2/NDUFA6/NDUFA10/NDUFB11/NDUFB8/NDUFA3/NDUFS3/NDUFS7/NDUFS6/NDUFA1	19
CC	GO:0030964	NADH dehydrogenase complex	19/2684	50/19717	1.455e-05	0.0006393	0.0004919	NDUFC1/NDUFA13/NDUFS4/NDUFB4/NDUFA4/NDUFA8/NDUFA2/NDUFB6/NDUFB7/NDUFB2/NDUFA6/NDUFA10/NDUFB11/NDUFB8/NDUFA3/NDUFS3/NDUFS7/NDUFS6/NDUFA1	19
CC	GO:0045271	respiratory chain complex I	19/2684	50/19717	1.455e-05	0.0006393	0.0004919	NDUFC1/NDUFA13/NDUFS4/NDUFB4/NDUFA4/NDUFA8/NDUFA2/NDUFB6/NDUFB7/NDUFB2/NDUFA6/NDUFA10/NDUFB11/NDUFB8/NDUFA3/NDUFS3/NDUFS7/NDUFS6/NDUFA1	19
CC	GO:0070469	respiratory chain	30/2684	100/19717	1.58e-05	0.0006556	0.0005044	COX7A1/NDUFC1/SDHC/NDUFA13/NDUFS4/NDUFA4L2/NDUFB4/NDUFA4/UQCR10/NDUFA8/CYC1/COX8A/NDUFA2/COX6A1/NDUFB6/NDUFB7/SDHD/NDUFB2/NDUFA6/NDUFA10/COA3/NDUFB11/NDUFB8/NDUFA3/UQCRQ/NDUFS3/NDUFS7/NDUFS6/NDUFA1/UQCRC1	30
CC	GO:0030662	coated vesicle membrane	46/2684	182/19717	1.777e-05	0.0006874	0.0005289	COPZ2/FOLR1/HLA-C/HLA-DRB4/SLC18A2/TFRC/SEC24A/HLA-F/HLA-G/IL7R/HLA-A/KDELR3/BTC/EGFR/EGF/AP1B1/APOE/TMED3/AP1G2/AP2M1/HLA-B/HLA-E/SEC22B/VTI1B/SEC13/ADRB2/VAMP3/CNIH1/SEC16A/VAMP7/CD3D/HBEGF/EREG/AP1S1/HLA-DQB1/AFTPH/TMED2/VAMP2/NRGN/TMED10/SYNRG/HIP1R/SYT1/CD3G/FZD2/CD59	46
CC	GO:0010008	endosome membrane	98/2684	479/19717	1.841e-05	0.0006874	0.0005289	MICALL1/TOM1L1/SPHK1/DIO3/HLA-C/CD320/HLA-DRB4/MREG/TFRC/YIPF2/STOML1/TBK1/PRAF2/LAMP3/ATP6V0D1/HLA-F/SH3GL1/VPS37C/HLA-G/ABHD6/HLA-A/RAB27A/TSPAN15/MTMR4/MMD/ZFYVE16/EGFR/TMEM9B/PIKFYVE/NTRK2/RAP2C/INSR/RABEPK/AP1G2/AP2M1/HLA-B/HLA-E/NDFIP1/ERBB2/EHD3/PDLIM4/VTI1B/PLD1/SNX17/CHMP6/TCIRG1/ACAP1/ADRB2/CMTM6/NTRK1/VAMP3/VPS16/SLC48A1/SNX2/CD63/MCOLN3/WLS/RAB13/CHMP2A/TMEM59/PSENEN/VAMP7/PML/IRAK4/ABCA2/HLA-DOB/ACAP2/EPHA4/SLC11A1/SORT1/HLA-DQB1/USP8/UBB/ATP6V0E2/WDR91/LAMTOR2/OPTN/ATP11B/SNX10/TPCN1/LAMP5/MCOLN1/WDR44/APH1B/CHMP1B/RAB11B/PARM1/CD164/MYD88/RAB15/TLR8/NPC1/FZD7/YIPF1/APH1A/SLC1A1/CLEC16A/DNAJC13	98
CC	GO:0030135	coated vesicle	65/2684	289/19717	2.422e-05	0.0008521	0.0006556	COPZ2/FOLR1/HLA-C/HLA-DRB4/SLC18A2/TFRC/SEC24A/TMED1/HLA-F/HLA-G/IL7R/HLA-A/RAB27A/KDELR3/SERPINA1/BTC/EGFR/EGF/CTLA4/AP1B1/YIF1A/APOE/TMED3/AP1G2/ASTN2/AP2M1/HLA-B/HLA-E/LMAN2/SEC22B/VTI1B/DENND1B/SEC13/F8/ADRB2/ERGIC3/VAMP3/VPS16/CNIH1/YIPF5/TEX261/SEC16A/VAMP7/CD3D/HBEGF/EREG/AP1S1/SORT1/HLA-DQB1/DENND1C/AFTPH/TMED2/VAMP2/NRGN/TMED9/TMED10/SYNRG/LMBRD1/HIP1R/SYT1/CD3G/CPNE6/FZD2/SFTPC/CD59	65
CC	GO:1990204	oxidoreductase complex	32/2684	112/19717	2.509e-05	0.0008521	0.0006556	PDK2/NDUFC1/SDHC/BCKDHB/NDUFA13/NDUFS4/NDUFB4/NDUFA4/UQCR10/NDUFA8/RRM2/CYC1/NDUFA2/NDUFB6/NDUFB7/SDHD/DLD/NDUFB2/NDUFA6/PDK1/NDUFA10/NDUFB11/PDHB/NDUFB8/NDUFA3/UQCRQ/NDUFS3/NDUFS7/NDUFS6/NDUFA1/UQCRC1/NCF1	32
CC	GO:0030134	COPII-coated ER to Golgi transport vesicle	28/2684	93/19717	2.782e-05	0.0009036	0.0006953	FOLR1/HLA-C/HLA-DRB4/SEC24A/TMED1/HLA-F/HLA-G/HLA-A/SERPINA1/YIF1A/TMED3/HLA-B/HLA-E/LMAN2/SEC22B/VTI1B/SEC13/F8/ERGIC3/CNIH1/YIPF5/TEX261/SEC16A/HLA-DQB1/TMED2/TMED9/TMED10/CD59	28
CC	GO:0001772	immunological synapse	15/2684	36/19717	3.229e-05	0.001005	0.0007734	SOCS6/GZMB/CD28/GZMA/ZAP70/CD81/CD3E/LCK/PRKCQ/LAT/RHOH/LGALS3/BCL10/STOML2/ATP2B1	15
CC	GO:0005925	focal adhesion	84/2684	405/19717	4.281e-05	0.001279	0.0009843	MTF2/CDH2/LCP1/JAK2/GAK/MAPK3/PRKAR2A/GIT2/TRIP6/LAP3/MRC2/PTPRC/ARL2/SYNE2/ITGBL1/ADAM17/EGFR/ITGA5/BSG/PDLIM1/ACTR3/NEDD9/ZFYVE21/CORO2B/RALA/JAK1/FAT1/EHD3/ARHGEF2/LPP/HNRNPK/RPS8/RPL12/ITGB7/TSPAN4/CAT/CD44/FERMT2/HSPB1/CD81/PPP1R12A/RPS11/TNS3/DCAF6/ARHGEF7/RAC2/MAP4K4/CLASP1/CD151/RPL10A/SORBS2/RPS5/TNS1/GNB2/FERMT1/ARPC5L/PARVB/TLN2/CTTN/PPIB/RPL8/ITGB5/RPL19/SLC9A3R2/FHL2/TLE2/MAPRE2/CYFIP1/LIMA1/SNTB1/ACTN1/FLNA/KRAS/PTK2B/ACTR2/HSPA5/HMGA1/ARHGAP26/FZD2/LPXN/CD59/RPLP0/SORBS1/PPFIBP1	84
CC	GO:0031091	platelet alpha granule	27/2684	91/19717	5.106e-05	0.001467	0.001129	CYB5R1/MAGED2/PROS1/SNCA/CLU/SERPINA3/SERPINA1/HGF/SERPINA5/EGF/SERPINE1/APLP2/CFD/PECAM1/VTI1B/F8/IGF1/VAMP7/PDGFB/VEGFA/THBS2/GTPBP2/TIMP1/SCCPDH/ACTN1/VEGFB/SRGN	27
CC	GO:0005924	cell-substrate adherens junction	84/2684	408/19717	5.621e-05	0.001555	0.001196	MTF2/CDH2/LCP1/JAK2/GAK/MAPK3/PRKAR2A/GIT2/TRIP6/LAP3/MRC2/PTPRC/ARL2/SYNE2/ITGBL1/ADAM17/EGFR/ITGA5/BSG/PDLIM1/ACTR3/NEDD9/ZFYVE21/CORO2B/RALA/JAK1/FAT1/EHD3/ARHGEF2/LPP/HNRNPK/RPS8/RPL12/ITGB7/TSPAN4/CAT/CD44/FERMT2/HSPB1/CD81/PPP1R12A/RPS11/TNS3/DCAF6/ARHGEF7/RAC2/MAP4K4/CLASP1/CD151/RPL10A/SORBS2/RPS5/TNS1/GNB2/FERMT1/ARPC5L/PARVB/TLN2/CTTN/PPIB/RPL8/ITGB5/RPL19/SLC9A3R2/FHL2/TLE2/MAPRE2/CYFIP1/LIMA1/SNTB1/ACTN1/FLNA/KRAS/PTK2B/ACTR2/HSPA5/HMGA1/ARHGAP26/FZD2/LPXN/CD59/RPLP0/SORBS1/PPFIBP1	84
CC	GO:0005759	mitochondrial matrix	94/2684	469/19717	6.112e-05	0.001631	0.001255	PDK2/NME4/IVD/ALDH7A1/MTHFD2/TK2/FECH/SNCA/ECHS1/ETFB/BCKDHB/ACSM5/ARL2/GLRX5/ME2/HSD17B10/DNA2/MECR/SUOX/PCCB/FDX1/SCO2/CYP11A1/BLOC1S1/HMGCL/DGUOK/GSTZ1/NUDT9/PC/GPX1/LIPT1/POLDIP2/MRPL24/NUBPL/MRPL11/HADH/MPG/FASTK/OXCT1/MDH2/ECI1/POLG/SIRT3/ACAT1/MPST/DLD/CCNB1/MRPL40/MRPL23/CPS1/PDK1/TRAP1/LYRM4/PCK2/ARL2BP/GFM1/NDUFA10/TXN2/OAT/DIMT1/ACP6/MRPS33/ACADM/SOD1/PDHB/MRPS28/NDUFB8/MRPS17/PUS1/SUCLG1/ACAA2/TYMS/NDUFS3/CREB1/CDK1/MRPS22/NDUFS7/MRPS11/MRPL17/MCAT/MRPL20/TFB2M/ERBB4/PYCR1/ALDH6A1/MIPEP/TXNRD2/MRPL18/MRPS14/STYXL1/FH/TRMT5/MRPL4/PPA2	94
CC	GO:0009897	external side of plasma membrane	81/2684	393/19717	7.274e-05	0.001874	0.001442	FCGRT/CXCL9/IL11RA/CXCL10/FOLR1/HLA-C/MS4A2/MAP3K5/BTN2A2/CRLF1/TFRC/IL27RA/BTN2A1/HLA-F/IL2RG/HLA-G/MICB/IL7R/HLA-A/PTPRC/SERPINA5/CD8A/SDC1/CTLA4/ITGA5/ITGAE/PRNP/CX3CR1/TNFRSF11A/ADA/INSR/TNFRSF14/CD83/GFRA1/HLA-B/HLA-E/PECAM1/KIT/HFE/IDE/CCR5/BTN3A3/EFNA5/IGHM/CD28/CD40/GRIA2/CXCR4/S1PR1/TRBC1/FOLR2/CDH5/CD3E/CD27/CD69/IL2RB/CD3D/CD19/CCR7/PRND/CXCR2/IGLL5/ULBP2/IGLC1/IL3RA/BTN3A1/ERMAP/CD2/IL6R/FCN1/GHR/CD3G/MS4A1/ANPEP/IL13RA2/TLR8/CCR2/CD40LG/BTNL2/CD59/CXCR6	81
CC	GO:0030055	cell-substrate junction	84/2684	412/19717	8.01e-05	0.00196	0.001508	MTF2/CDH2/LCP1/JAK2/GAK/MAPK3/PRKAR2A/GIT2/TRIP6/LAP3/MRC2/PTPRC/ARL2/SYNE2/ITGBL1/ADAM17/EGFR/ITGA5/BSG/PDLIM1/ACTR3/NEDD9/ZFYVE21/CORO2B/RALA/JAK1/FAT1/EHD3/ARHGEF2/LPP/HNRNPK/RPS8/RPL12/ITGB7/TSPAN4/CAT/CD44/FERMT2/HSPB1/CD81/PPP1R12A/RPS11/TNS3/DCAF6/ARHGEF7/RAC2/MAP4K4/CLASP1/CD151/RPL10A/SORBS2/RPS5/TNS1/GNB2/FERMT1/ARPC5L/PARVB/TLN2/CTTN/PPIB/RPL8/ITGB5/RPL19/SLC9A3R2/FHL2/TLE2/MAPRE2/CYFIP1/LIMA1/SNTB1/ACTN1/FLNA/KRAS/PTK2B/ACTR2/HSPA5/HMGA1/ARHGAP26/FZD2/LPXN/CD59/RPLP0/SORBS1/PPFIBP1	84
CC	GO:0005777	peroxisome	35/2684	134/19717	8.395e-05	0.00196	0.001508	FIS1/ECI2/PEX10/PMVK/EPHX2/ACOX2/PEX19/DECR2/IMPDH2/DDO/TTC1/PHYH/IDE/HMGCL/PXMP2/ECH1/PEX7/PEX11A/CAT/PEX2/SCP2/GRHPR/ALDH3A2/SERHL2/PEX12/PEX14/SOD1/ACOX1/AGPS/ACOT8/MPV17/FAR2/CRAT/PXMP4/MVK	35
CC	GO:0042579	microbody	35/2684	134/19717	8.395e-05	0.00196	0.001508	FIS1/ECI2/PEX10/PMVK/EPHX2/ACOX2/PEX19/DECR2/IMPDH2/DDO/TTC1/PHYH/IDE/HMGCL/PXMP2/ECH1/PEX7/PEX11A/CAT/PEX2/SCP2/GRHPR/ALDH3A2/SERHL2/PEX12/PEX14/SOD1/ACOX1/AGPS/ACOT8/MPV17/FAR2/CRAT/PXMP4/MVK	35
CC	GO:0030176	integral component of endoplasmic reticulum membrane	38/2684	150/19717	8.69e-05	0.001967	0.001513	TAP1/PIGT/GPAA1/HLA-C/HLA-DRB4/BNIP1/HLA-F/PIGK/HLA-G/HLA-A/DHRS9/TECR/RTN2/SLC27A5/HLA-B/HLA-E/DPM3/TAPBP/FKBP8/DPAGT1/ERGIC3/TMCO1/ATF6/TEX261/TBL2/HLA-DQB1/EMC2/TAP2/DHCR7/ANKLE2/EDEM1/SGMS1/UBXN8/XBP1/SGPL1/EMC9/EMC7/HSPA5	38
CC	GO:0101002	ficolin-1-rich granule	44/2684	185/19717	0.000125	0.002747	0.002113	SLC2A3/NBEAL2/CRISPLD2/GUSB/LILRB2/SERPINA1/IMPDH2/ITGAX/PGM1/TIMP2/CFD/SERPINB6/CSNK2B/ASAH1/PSMC2/CAT/TCIRG1/CD93/PNP/CR1/APAF1/QPCT/PTPRN2/PSMC3/HSPA6/SLC11A1/HMGB1/COMMD9/KPNB1/PPIE/CD58/HBB/GAA/GSDMD/ALDOC/FCN1/KRT1/LGALS3/MVP/PDAP1/UBR4/ACTR2/AMPD3/ARSB	44
CC	GO:0031227	intrinsic component of endoplasmic reticulum membrane	39/2684	158/19717	0.0001288	0.002748	0.002114	TAP1/PIGT/GPAA1/HLA-C/HLA-DRB4/BNIP1/HLA-F/PIGK/HLA-G/HLA-A/DHRS9/TECR/RTN2/SLC27A5/HLA-B/HLA-E/DPM3/TAPBP/FKBP8/DPAGT1/ERGIC3/TMCO1/ATF6/TEX261/TBL2/HLA-DQB1/EMC2/TAP2/DHCR7/ANKLE2/EDEM1/SGMS1/UBXN8/XBP1/PGAP3/SGPL1/EMC9/EMC7/HSPA5	39
CC	GO:1902911	protein kinase complex	29/2684	109/19717	0.0002333	0.004841	0.003725	SIK1/MAP3K5/PRKAR2A/CCNA2/UVRAG/CKS1B/INSR/CDK4/PRKAG1/PRKAB1/MMS19/CKS2/CCNT2/CCNB2/CHUK/CCNB1/CCNH/ATG13/CCNK/ERCC2/PRKAA1/IKBKG/CDK1/CCND2/CDKN1A/MNAT1/GTF2H3/CDK9/SORBS1	29
CC	GO:0005778	peroxisomal membrane	19/2684	60/19717	0.0002528	0.004964	0.003819	FIS1/PEX10/PEX19/DECR2/IMPDH2/TTC1/PXMP2/PEX7/PEX11A/CAT/PEX2/ALDH3A2/PEX12/PEX14/ACOX1/AGPS/MPV17/FAR2/PXMP4	19
CC	GO:0031903	microbody membrane	19/2684	60/19717	0.0002528	0.004964	0.003819	FIS1/PEX10/PEX19/DECR2/IMPDH2/TTC1/PXMP2/PEX7/PEX11A/CAT/PEX2/ALDH3A2/PEX12/PEX14/ACOX1/AGPS/MPV17/FAR2/PXMP4	19
CC	GO:0005782	peroxisomal matrix	17/2684	51/19717	0.0002658	0.004964	0.003819	ECI2/EPHX2/ACOX2/DDO/PHYH/IDE/HMGCL/ECH1/PEX7/CAT/SCP2/GRHPR/ACOX1/AGPS/ACOT8/FAR2/CRAT	17
CC	GO:0031907	microbody lumen	17/2684	51/19717	0.0002658	0.004964	0.003819	ECI2/EPHX2/ACOX2/DDO/PHYH/IDE/HMGCL/ECH1/PEX7/CAT/SCP2/GRHPR/ACOX1/AGPS/ACOT8/FAR2/CRAT	17
CC	GO:0031965	nuclear membrane	62/2684	296/19717	0.000308	0.005611	0.004317	GCH1/LTC4S/GCHFR/IL15RA/LBR/ATP2A3/SNCA/ALOX5AP/SIGMAR1/CLMN/SMAD3/OSBPL3/SYNE2/NUP153/EGFR/NDUFB4/PRNP/NPAP1/PUM2/CERS6/CDK4/DNAJB14/TPR/DNAJC1/OSBPL8/NUP50/LMNB1/SCRN1/CERS4/RANBP2/DPY19L2P2/TOR1AIP1/CLCA2/CERS2/RBM15/PCM1/PTGDS/NUP210/SORT1/DUSP2/MTDH/CUEDC2/P2RX4/DTL/DHCR7/KPNB1/ATP11B/SPAST/NDC1/YBX1/TXNL4A/PHF11/SEPHS1/CCND2/PHLPP1/HOXA7/UNC50/VAPA/LPIN1/NUP98/TMEM97/NUP62	62
CC	GO:0043025	neuronal cell body	95/2684	497/19717	0.0003298	0.005866	0.004513	BRINP1/SLC2A3/SCN1B/KCNN3/CD200/TNFRSF1B/STMN2/UNC5C/BRINP3/SNCA/TMEM100/UCHL1/PTPRF/SOS1/PDE1A/GLRX5/SLC38A2/NDN/TPX2/BAIAP2/CX3CR1/TIMP2/NQO1/ATXN10/ADA/APOE/INSR/ASTN2/PENK/ARHGEF2/ENO2/PGRMC1/VTI1B/GDPD5/KLHL24/KCNJ2/FZD3/GPM6A/CRYAB/NTRK1/VPS16/OMP/KIF5C/ARHGEF7/CHRNA3/ASS1/CRHBP/SNCAIP/ANG/TOP1/PTBP2/EPHA4/SORT1/TXN2/P2RX4/UBB/PNOC/CPE/S100A5/PTPRK/SOD1/NRGN/AGRP/SRR/KATNB1/KCNN2/AKAP9/HDAC1/PRKAA1/TAC1/CIB1/BRINP2/PMM1/GAL/HIP1R/NDUFS7/KCND1/NCDN/CYFIP1/FABP7/FLNA/PTK2B/DSCAM/CCR2/SEZ6L/TMPRSS5/SERPINF1/PLXDC1/CPNE6/MYH10/ATP2B1/LRIG2/TH/STAU1/NCF1	95
CC	GO:0030670	phagocytic vesicle membrane	22/2684	76/19717	0.0003605	0.006262	0.004818	TAP1/HLA-C/ATP6V0D1/HLA-F/HLA-G/HLA-A/HLA-B/HLA-E/SEC22B/RAB11FIP1/TAPBP/TCIRG1/VAMP3/RAC2/VAMP7/SLC11A1/TAP2/ATP6V0E2/MCOLN1/RAB20/RAB11B/ATG12	22
CC	GO:0031093	platelet alpha granule lumen	20/2684	67/19717	0.0004226	0.007175	0.00552	MAGED2/PROS1/CLU/SERPINA3/SERPINA1/HGF/EGF/SERPINE1/CFD/VTI1B/F8/IGF1/PDGFB/VEGFA/GTPBP2/TIMP1/SCCPDH/ACTN1/VEGFB/SRGN	20
CC	GO:0072686	mitotic spindle	28/2684	109/19717	0.0005501	0.009132	0.007026	CDC7/ECT2/ASPM/HAUS3/TPX2/TADA3/RACGAP1/TPR/MAPRE3/NUSAP1/SPAG5/CDC14A/KIF18B/EML1/CENPE/KIF11/AURKB/IQCB1/AGBL5/NCOR1/SMC1A/YEATS2/CTTN/IKBKG/TACC3/CDK1/EML4/NUP62	28
CC	GO:0098589	membrane region	66/2684	328/19717	0.0006388	0.0101	0.007767	SGCA/DYSF/ATP1B1/CDH2/TNFRSF1B/BIRC3/JAK2/FXYD1/MAPK3/PRKAR2A/STOML1/ANGPT1/KCNQ1/FAS/ERLIN2/OLR1/CFLAR/PTPRC/RFTN1/CD8A/ADAM17/EGFR/PIKFYVE/PRNP/BSG/INSR/BIRC2/PECAM1/EFNA5/PLVAP/SELE/TFPI/RANBP2/S1PR1/ZAP70/F2R/CBLB/LCK/CHRNA3/NOS3/EFNB1/KDR/GHSR/ADCY1/CD19/LAMTOR2/LAT/EMP2/HAS2/CD2/RANGRF/ATP2B4/ADCY2/BCL10/CXADR/MS4A1/KRAS/LCP2/PTK2B/NPC1/SMO/STOML2/PODXL/ATP2B1/NUP62/SORBS1	66
CC	GO:0098857	membrane microdomain	64/2684	316/19717	0.0006408	0.0101	0.007767	SGCA/DYSF/ATP1B1/CDH2/TNFRSF1B/BIRC3/JAK2/FXYD1/MAPK3/PRKAR2A/STOML1/ANGPT1/KCNQ1/FAS/ERLIN2/OLR1/CFLAR/PTPRC/RFTN1/CD8A/ADAM17/EGFR/PIKFYVE/PRNP/BSG/INSR/BIRC2/PECAM1/EFNA5/PLVAP/SELE/TFPI/S1PR1/ZAP70/F2R/CBLB/LCK/CHRNA3/NOS3/EFNB1/KDR/GHSR/ADCY1/CD19/LAMTOR2/LAT/EMP2/HAS2/CD2/RANGRF/ATP2B4/ADCY2/BCL10/CXADR/MS4A1/KRAS/LCP2/PTK2B/NPC1/SMO/STOML2/PODXL/ATP2B1/SORBS1	64
CC	GO:0005758	mitochondrial intermembrane space	22/2684	79/19717	0.0006487	0.0101	0.007767	NME4/CHCHD2/SNCA/ARL2/TIMM10/PINK1/NDUFA8/SUOX/BLOC1S1/CMC4/FGR/CAT/NDUFB7/GATM/MYOC/TRAP1/ARL2BP/MICU1/SOD1/CPOX/GOLPH3/STOML2	22
CC	GO:0000307	cyclin-dependent protein kinase holoenzyme complex	14/2684	42/19717	0.0009076	0.01362	0.01048	CCNA2/CKS1B/CDK4/CKS2/CCNT2/CCNB2/CCNB1/CCNH/CCNK/CDK1/CCND2/CDKN1A/MNAT1/CDK9	14
CC	GO:0005774	vacuolar membrane	79/2684	412/19717	0.0009116	0.01362	0.01048	SLC22A17/HLA-DRB4/TM6SF1/MREG/ENPP1/GABARAPL1/LAMP3/ATP6V0D1/HLA-F/GABARAPL2/ABHD6/ATRAID/ABCC10/MMD/ENTPD4/SPG11/CTSA/EGF/TMEM9B/AP1B1/UVRAG/DRAM1/AP2M1/RRAGA/TSPAN1/BLOC1S1/TMEM30A/VTI1B/SLC2A6/PLD1/SEC13/MAN2B2/TCIRG1/ARRB1/CMTM6/VPS16/SLC48A1/CD63/CYBRD1/MCOLN3/ABCC1/LRMP/TMEM59/VAMP7/ABCA2/HLA-DOB/ITM2C/ATP8A1/AP1S1/SORT1/HLA-DQB1/KXD1/LNPEP/P2RX4/GNB2/LAMTOR2/CP/DDOST/NEU1/ATP11B/WDR11/GAA/TPCN1/LAMP5/MCOLN1/LMBRD1/RRAGD/VNN1/CD164/ANPEP/RAP1B/TLR8/NPC1/VAPA/NAPA/GABARAP/PSAP/CLEC16A/DNAJC13	79
CC	GO:0055038	recycling endosome membrane	22/2684	81/19717	0.000937	0.01372	0.01056	MICALL1/HLA-C/HLA-F/HLA-G/HLA-A/RAP2C/HLA-B/HLA-E/EHD3/PDLIM4/VTI1B/ACAP1/CMTM6/NTRK1/VAMP3/RAB13/OPTN/ATP11B/LAMP5/RAB11B/FZD7/SLC1A1	22
CC	GO:0045121	membrane raft	63/2684	315/19717	0.0009817	0.0141	0.01085	SGCA/ATP1B1/CDH2/TNFRSF1B/BIRC3/JAK2/FXYD1/MAPK3/PRKAR2A/STOML1/ANGPT1/KCNQ1/FAS/ERLIN2/OLR1/CFLAR/PTPRC/RFTN1/CD8A/ADAM17/EGFR/PIKFYVE/PRNP/BSG/INSR/BIRC2/PECAM1/EFNA5/PLVAP/SELE/TFPI/S1PR1/ZAP70/F2R/CBLB/LCK/CHRNA3/NOS3/EFNB1/KDR/GHSR/ADCY1/CD19/LAMTOR2/LAT/EMP2/HAS2/CD2/RANGRF/ATP2B4/ADCY2/BCL10/CXADR/MS4A1/KRAS/LCP2/PTK2B/NPC1/SMO/STOML2/PODXL/ATP2B1/SORBS1	63
CC	GO:1904813	ficolin-1-rich granule lumen	30/2684	124/19717	0.001037	0.01462	0.01125	CRISPLD2/GUSB/SERPINA1/IMPDH2/PGM1/TIMP2/CFD/CSNK2B/ASAH1/PSMC2/CAT/PNP/APAF1/QPCT/PSMC3/HSPA6/HMGB1/COMMD9/KPNB1/PPIE/HBB/GSDMD/ALDOC/FCN1/KRT1/MVP/PDAP1/ACTR2/AMPD3/ARSB	30
CC	GO:0005770	late endosome	53/2684	256/19717	0.001067	0.01476	0.01136	MICALL1/DYSF/LGMN/HLA-DRB4/MREG/MAPK3/YIPF2/STOML1/LAMP3/KCNQ1/VPS37C/ABHD6/RAB27A/TSPAN15/SDF4/MMD/EGFR/PIKFYVE/UVRAG/ASTN2/TMEM230/MAGI2/VTI1B/PLD1/CXCR4/CHMP6/TCIRG1/F2R/NTRK1/VPS16/CD63/MCOLN3/CRHBP/CHMP2A/TMEM59/VAMP7/SLC31A2/SLC11A1/WDR91/AP1AR/CST7/LAMTOR2/LAMP5/MCOLN1/CHMP1B/PARM1/NPC1/YIPF1/PSAP/CLEC16A/DDIT3/NEDD4L/SFTPC	53
CC	GO:0012507	ER to Golgi transport vesicle membrane	18/2684	62/19717	0.001153	0.01565	0.01204	FOLR1/HLA-C/HLA-DRB4/SEC24A/HLA-F/HLA-G/HLA-A/HLA-B/HLA-E/SEC22B/VTI1B/SEC13/CNIH1/SEC16A/HLA-DQB1/TMED2/TMED10/CD59	18
CC	GO:0016607	nuclear speck	76/2684	397/19717	0.001181	0.01565	0.01204	SMC6/AR/SLC2A4RG/STK19/IL15/TRIM22/CBY1/SNRNP40/FTO/TRIP12/ZNF217/THOC2/BARD1/CCNL1/DDX39A/SF3B1/THOC1/SART3/ZNF638/MOCS2/PRPF4B/AKAP17A/FNBP4/FIBP/GCAT/DENND1B/SMC5/PPP1R16B/DDX46/NXF1/TATDN2/MAML1/ASCC3/DGKZ/GATAD2A/RBM15/SETD1B/PSKH1/ARL6IP4/NAMPT/SRSF4/CSNK1A1/SRSF8/PIN1/TAP2/SFPQ/PPIE/KAT6A/ACADM/SMC4/WRN/RBM39/HIF1A/SRP54/PRKAA1/IFI16/TARDBP/RBM19/ATPAF2/SREK1/TCF3/RAF1/MPP1/YTHDC1/ASCC1/CXXC1/SON/RING1/OSGEP/BAZ2A/MORF4L1/BDNF/CCNL2/RNF34/PPIH/LPXN	76
CC	GO:0005765	lysosomal membrane	69/2684	354/19717	0.001194	0.01565	0.01204	HLA-DRB4/TM6SF1/MREG/ENPP1/LAMP3/ATP6V0D1/HLA-F/ABHD6/ATRAID/ABCC10/MMD/SPG11/CTSA/EGF/TMEM9B/AP1B1/DRAM1/AP2M1/RRAGA/TSPAN1/BLOC1S1/TMEM30A/VTI1B/SLC2A6/PLD1/SEC13/TCIRG1/ARRB1/CMTM6/VPS16/SLC48A1/CD63/CYBRD1/MCOLN3/LRMP/TMEM59/VAMP7/ABCA2/HLA-DOB/ITM2C/ATP8A1/AP1S1/SORT1/HLA-DQB1/KXD1/LNPEP/P2RX4/GNB2/LAMTOR2/CP/DDOST/NEU1/ATP11B/WDR11/GAA/TPCN1/LAMP5/MCOLN1/LMBRD1/VNN1/CD164/ANPEP/RAP1B/TLR8/NPC1/VAPA/PSAP/CLEC16A/DNAJC13	69
CC	GO:0055037	recycling endosome	39/2684	176/19717	0.001271	0.01616	0.01243	MICALL1/HLA-C/TFRC/HLA-F/MICALL2/HLA-G/HLA-A/SYT11/TNIK/FCHSD2/AVL9/MCTP1/RAP2C/HLA-B/HLA-E/HFE/TMEM230/EHD3/PDLIM4/VTI1B/RAB11FIP1/GPER1/ACAP1/CMTM6/NTRK1/VAMP3/VPS16/RAB13/DYNC1I1/SLC31A2/OPTN/AMOTL2/ATP11B/LAMP5/AQP2/RAB11B/ST8SIA2/FZD7/SLC1A1	39
CC	GO:0098852	lytic vacuole membrane	69/2684	355/19717	0.001289	0.01616	0.01243	HLA-DRB4/TM6SF1/MREG/ENPP1/LAMP3/ATP6V0D1/HLA-F/ABHD6/ATRAID/ABCC10/MMD/SPG11/CTSA/EGF/TMEM9B/AP1B1/DRAM1/AP2M1/RRAGA/TSPAN1/BLOC1S1/TMEM30A/VTI1B/SLC2A6/PLD1/SEC13/TCIRG1/ARRB1/CMTM6/VPS16/SLC48A1/CD63/CYBRD1/MCOLN3/LRMP/TMEM59/VAMP7/ABCA2/HLA-DOB/ITM2C/ATP8A1/AP1S1/SORT1/HLA-DQB1/KXD1/LNPEP/P2RX4/GNB2/LAMTOR2/CP/DDOST/NEU1/ATP11B/WDR11/GAA/TPCN1/LAMP5/MCOLN1/LMBRD1/VNN1/CD164/ANPEP/RAP1B/TLR8/NPC1/VAPA/PSAP/CLEC16A/DNAJC13	69
CC	GO:0016591	RNA polymerase II, holoenzyme	22/2684	83/19717	0.00133	0.01616	0.01243	ERCC1/WDR61/POLR2J/POLR2I/POLR2L/POLR2E/POLR2F/TADA3/MMS19/SETD5/POLR2C/TAF10/PEX2/GTF2A2/TRRAP/CCNH/TAF9B/POLR2G/TAF7/ERCC2/MNAT1/GTF2H3	22
CC	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	30/2684	126/19717	0.001362	0.01616	0.01243	COPZ2/TAP1/FOLR1/TMED1/STK17B/LRPAP1/SERPINA1/YIF1A/TMED3/LMAN2/SEC22B/MTMR6/TAPBP/F8/PTPN2/ERGIC3/CNIH1/HMGB1/TAP2/TMED2/GOLGB1/TMED9/TMED10/LAMP5/ERP44/PRRG4/NUCB1/ANPEP/HSPA5/CD59	30
CC	GO:0035861	site of double-strand break	17/2684	58/19717	0.001393	0.01616	0.01243	SMC6/PARP3/SMCHD1/ARPC1A/NBN/RFWD3/ACTR3/SAMHD1/RPA3/RNF138/SMC5/SETMAR/RAD50/TIMELESS/ATF2/ACTR2/WDR70	17
CC	GO:0018995	host	20/2684	73/19717	0.001396	0.01616	0.01243	GBP2/VPS37C/NUP160/NUP153/KPNA2/TPR/NUP50/SEC13/RANBP2/AXL/NUP210/UBB/TOP2A/KPNB1/NUP43/NDC1/KPNA1/KPNA3/NUP98/NUP62	20
CC	GO:0043657	host cell	20/2684	73/19717	0.001396	0.01616	0.01243	GBP2/VPS37C/NUP160/NUP153/KPNA2/TPR/NUP50/SEC13/RANBP2/AXL/NUP210/UBB/TOP2A/KPNB1/NUP43/NDC1/KPNA1/KPNA3/NUP98/NUP62	20
CC	GO:0005769	early endosome	68/2684	350/19717	0.001406	0.01616	0.01243	DYSF/SPHK1/HLA-C/CYTIP/TFRC/MAPK3/LAMP3/ATP6V0D1/KCNQ1/HLA-F/SH3GL1/HLA-G/HLA-A/MTMR4/RFTN1/ZFYVE16/EGFR/TMEM9B/PIKFYVE/UVRAG/NTRK2/APOE/ASTN2/HLA-B/HLA-E/HFE/TMEM230/PDLIM4/TRAK1/VTI1B/RABEP2/PHB/GPER1/CXCR4/SNX17/F2R/ADRB2/CMTM6/NTRK1/RABGAP1L/VPS16/SNX2/DIAPH2/TBC1D16/MCOLN3/WLS/KDR/RND2/PML/MAGEL2/EPHA4/SORT1/LNPEP/USP8/VPS8/WDR91/AP1AR/ATP11B/LAMP5/NF2/RAB20/PARM1/ST8SIA2/NUCB1/APH1A/SLC1A1/AP4M1/DNAJC13	68
CC	GO:0005766	primary lysosome	35/2684	155/19717	0.001557	0.01736	0.01336	FUCA1/GUSB/SERPINA3/CTSA/PRDX6/C6orf120/RNASE2/TMEM30A/TOLLIP/GGH/ELANE/CMTM6/HEXA/CD63/FTL/LRMP/VAMP7/GM2A/ATP8A1/DYNC1H1/DDOST/ATP11B/DNAJC3/GAA/PADI2/CYB5R3/GCA/CTSG/VNN1/RAP1B/VAPA/ACTR2/PSAP/ARSB/DNAJC13	35
CC	GO:0042582	azurophil granule	35/2684	155/19717	0.001557	0.01736	0.01336	FUCA1/GUSB/SERPINA3/CTSA/PRDX6/C6orf120/RNASE2/TMEM30A/TOLLIP/GGH/ELANE/CMTM6/HEXA/CD63/FTL/LRMP/VAMP7/GM2A/ATP8A1/DYNC1H1/DDOST/ATP11B/DNAJC3/GAA/PADI2/CYB5R3/GCA/CTSG/VNN1/RAP1B/VAPA/ACTR2/PSAP/ARSB/DNAJC13	35
CC	GO:0030666	endocytic vesicle membrane	37/2684	167/19717	0.001671	0.01835	0.01412	TAP1/HLA-C/WNT5B/HLA-DRB4/COLEC12/ATP6V0D1/HLA-F/HLA-G/HLA-A/APOE/AP2M1/HLA-B/HLA-E/SEC22B/RAB11FIP1/TAPBP/GRIA2/TCIRG1/VAMP3/WLS/NOS3/RAC2/VAMP7/HBEGF/SLC11A1/HLA-DQB1/UBB/TAP2/ATP6V0E2/MCOLN1/RAB20/RAB11B/HIP1R/ATG12/SMO/CAMK2B/FZD2	37
CC	GO:0005876	spindle microtubule	17/2684	59/19717	0.001713	0.01854	0.01427	TUBG2/ARL3/KIF2A/HAUS2/MAPRE3/NUSAP1/KNTC1/KIF18B/PRC1/CENPE/KIF11/KIF4A/CLASP1/AURKB/PARP4/BIRC5/CDK1	17
CC	GO:0098798	mitochondrial protein complex	53/2684	262/19717	0.001827	0.01949	0.015	PDK2/NDUFC1/SDHC/BCKDHB/NDUFA13/NDUFS4/NDUFA4L2/TIMM10/HSD17B10/DNA2/NDUFB4/NDUFA4/UQCR10/NDUFA8/APOO/CYC1/MRPL24/NDUFA2/MRPL11/COX6A1/NDUFB6/NDUFB7/SDHD/POLG/ANKZF1/NDUFB2/MRPL40/MRPL23/NDUFA6/PDK1/NDUFA10/COA3/NDUFB11/MICU1/MRPS33/MRPS28/NDUFB8/NDUFA3/MRPS17/UQCRQ/NDUFS3/MRPS22/NDUFS7/MRPS11/MRPL17/MRPL20/NDUFS6/SAMM50/MRPL18/MRPS14/NDUFA1/UQCRC1/MRPL4	53
CC	GO:0005665	RNA polymerase II, core complex	7/2684	15/19717	0.002029	0.02134	0.01642	POLR2J/POLR2I/POLR2L/POLR2E/POLR2F/POLR2C/POLR2G	7
CC	GO:0098687	chromosomal region	67/2684	349/19717	0.002069	0.02147	0.01652	SMC6/SETX/SMCHD1/DCLRE1C/ZNF330/ERCC1/HNRNPA2B1/NBN/NDE1/ATR/DNMT1/NUP160/CHEK2/TNKS2/CHEK1/SS18L1/EZH2/ATM/THOC2/DNA2/ORC3/UVRAG/DCTN6/NHP2/RPA1/THOC1/DCTN3/TPR/BUB1B/SPAG5/SMC5/SEC13/CDCA8/KNTC1/NDC80/PPP1R12A/DCTN2/DAXX/CENPE/CCNB1/NCAPG/DYNC1I1/MIS12/BRCA2/CLASP1/PML/ATRX/HMBOX1/CSNK1A1/AURKB/HJURP/RAD50/BIRC5/CENPT/NABP2/WRN/NUP43/SMC1A/SUV39H2/CDK1/CENPC/KAT2B/PIWIL2/CEBPB/NUP98/CENPF/SIRT7	67
CC	GO:0098800	inner mitochondrial membrane protein complex	31/2684	135/19717	0.002119	0.02168	0.01668	NDUFC1/SDHC/NDUFA13/NDUFS4/NDUFA4L2/TIMM10/NDUFB4/NDUFA4/UQCR10/NDUFA8/APOO/CYC1/NDUFA2/COX6A1/NDUFB6/NDUFB7/SDHD/NDUFB2/NDUFA6/NDUFA10/COA3/NDUFB11/MICU1/NDUFB8/NDUFA3/UQCRQ/NDUFS3/NDUFS7/NDUFS6/NDUFA1/UQCRC1	31
CC	GO:0000793	condensed chromosome	46/2684	223/19717	0.002361	0.02384	0.01834	SMC6/TOPBP1/NDE1/CHEK1/SS18L1/DCTN6/MKI67/DCTN3/UBE2I/BUB1B/SPAG5/SMC5/NCAPH/SETMAR/KNTC1/NDC80/BANF1/CENPE/CCNB1/NCAPG/DYNC1I1/MIS12/BRCA2/CLASP1/ATRX/CSNK1A1/AURKB/HMGB1/HJURP/RAD50/BIRC5/TOP2A/CENPT/RAD1/SMC4/NUP43/SMARCA5/AKAP8/AGO3/SMC1A/RAD9A/CENPC/HSPA2/SYN1/CEBPB/CENPF	46
CC	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane	19/2684	71/19717	0.002442	0.02415	0.01858	COPZ2/TAP1/FOLR1/TMED1/SERPINA1/TMED3/LMAN2/SEC22B/TAPBP/F8/ERGIC3/CNIH1/TAP2/TMED2/TMED9/TMED10/LAMP5/PRRG4/CD59	19
CC	GO:0030136	clathrin-coated vesicle	40/2684	188/19717	0.002457	0.02415	0.01858	FOLR1/HLA-DRB4/SLC18A2/TFRC/IL7R/RAB27A/BTC/EGFR/EGF/CTLA4/AP1B1/APOE/AP1G2/ASTN2/AP2M1/DENND1B/ADRB2/VAMP3/VPS16/VAMP7/CD3D/HBEGF/EREG/AP1S1/SORT1/HLA-DQB1/DENND1C/AFTPH/VAMP2/NRGN/TMED9/TMED10/SYNRG/LMBRD1/HIP1R/SYT1/CD3G/CPNE6/FZD2/SFTPC	40
CC	GO:0030660	Golgi-associated vesicle membrane	27/2684	114/19717	0.002495	0.0242	0.01862	COPZ2/FOLR1/HLA-C/HLA-DRB4/SEC24A/HLA-F/HLA-G/HLA-A/KDELR3/ZDHHC17/TMED3/AP1G2/HLA-B/HLA-E/SEC22B/VTI1B/SEC13/CNIH1/SEC16A/AP1S1/HLA-DQB1/AFTPH/TMED2/NRGN/TMED10/SYNRG/CD59	27
CC	GO:0030139	endocytic vesicle	59/2684	303/19717	0.002649	0.02501	0.01924	TAP1/DYSF/SPHK1/HLA-C/WNT5B/HLA-DRB4/COLEC12/ATP6V0D1/HLA-F/HLA-G/HLA-A/SYT11/HSPH1/EGFR/CTLA4/UVRAG/APOE/RALA/AP2M1/HLA-B/HLA-E/SEC22B/EHD3/PIK3C2B/PLD1/RAB11FIP1/TAPBP/GRIA2/TCIRG1/ELANE/VAMP3/WLS/GNLY/NOS3/RAB13/RAC2/RAPGEF6/VAMP7/HBEGF/SLC11A1/HLA-DQB1/UBB/TAP2/ATP6V0E2/HBB/MCOLN1/LPAR2/RAB20/ITGB5/LMBRD1/RAB11B/HIP1R/ATG12/SMO/CAMK2B/CPNE6/FZD2/SFTPC/NCF1	59
CC	GO:0005667	transcription factor complex	69/2684	365/19717	0.002674	0.02501	0.01924	PITX1/SIX1/HOXA11/CEBPA/HOXA10/SOX9/ERCC1/SMAD3/TCF7/ATF7IP/NCOA6/BRF2/REL/PDLIM1/TADA3/RUNX3/CDK4/TAF1D/ING2/RXRA/MMS19/LEF1/BEX1/PPARG/POU2F1/FOXF1/TAF10/NAA16/GTF2A2/SIX2/TRRAP/CCNH/NR1H2/TAF9B/RBPJ/TAF7/DEAF1/MED23/SFPQ/MED7/KAT5/HIF1A/RCOR1/TLE3/ERCC2/HDAC1/PTOV1/SIX6/SIX3/TCF3/CREB1/MED27/ASCC1/TCF7L2/TLE2/MNAT1/EP300/GTF2H3/CEBPB/NR5A2/ATF4/NFYC/PBX3/HMGA1/GTF3C5/DDIT3/RBL2/SATB2/NR1D2	69
CC	GO:0090543	Flemming body	10/2684	28/19717	0.002715	0.02501	0.01924	CNTRL/USP3/RACGAP1/RALA/EXOC7/CEP55/EXOC2/CENPC/EXOC1/NUP62	10
CC	GO:0044215	other organism	20/2684	77/19717	0.002794	0.02501	0.01924	GBP2/VPS37C/NUP160/NUP153/KPNA2/TPR/NUP50/SEC13/RANBP2/AXL/NUP210/UBB/TOP2A/KPNB1/NUP43/NDC1/KPNA1/KPNA3/NUP98/NUP62	20
CC	GO:0044216	other organism cell	20/2684	77/19717	0.002794	0.02501	0.01924	GBP2/VPS37C/NUP160/NUP153/KPNA2/TPR/NUP50/SEC13/RANBP2/AXL/NUP210/UBB/TOP2A/KPNB1/NUP43/NDC1/KPNA1/KPNA3/NUP98/NUP62	20
CC	GO:0044217	other organism part	20/2684	77/19717	0.002794	0.02501	0.01924	GBP2/VPS37C/NUP160/NUP153/KPNA2/TPR/NUP50/SEC13/RANBP2/AXL/NUP210/UBB/TOP2A/KPNB1/NUP43/NDC1/KPNA1/KPNA3/NUP98/NUP62	20
CC	GO:0005743	mitochondrial inner membrane	86/2684	473/19717	0.002826	0.02501	0.01924	NME4/COX7A1/NDUFC1/FECH/SNCA/CLU/SLC25A4/NDUFAF3/SDHC/NDUFA13/NDUFS4/MPC2/NDUFA4L2/TIMM10/SLC25A1/NDUFB4/PINK1/NDUFA4/UQCR10/NDUFA8/TMEM11/SCO2/CYP11A1/UQCC1/APOO/GCAT/COQ6/CYC1/PHB/COX6C/FGR/COX8A/MRPL24/NDUFA2/TAZ/MRPL11/COX6A1/NDUFB6/NDUFB7/SDHD/GATM/NDUFB2/MRPL40/MRPL23/NDUFA6/CPS1/MYOC/TRAP1/COX5B/NDUFA10/COA3/MTCH1/NDUFB11/MICU1/MRPS33/COQ9/MRPS28/NDUFB8/NDUFA3/MRPS17/UQCRQ/TYMS/NDUFS3/CPOX/MRPS22/MPV17/NDUFS7/MRPS11/MRPL17/SFXN1/LGALS3/MRPL20/COQ2/NDUFS6/SLC25A11/CRAT/MRPL18/YME1L1/MRPS14/ALDH18A1/MPC1/STOML2/NDUFA1/LETM1/UQCRC1/MRPL4	86
CC	GO:0030665	clathrin-coated vesicle membrane	27/2684	115/19717	0.002846	0.02501	0.01924	HLA-DRB4/SLC18A2/TFRC/IL7R/BTC/EGFR/EGF/AP1B1/APOE/AP1G2/AP2M1/ADRB2/VAMP3/VAMP7/CD3D/HBEGF/EREG/AP1S1/HLA-DQB1/AFTPH/VAMP2/NRGN/SYNRG/HIP1R/SYT1/CD3G/FZD2	27
CC	GO:0005798	Golgi-associated vesicle	38/2684	178/19717	0.002918	0.02534	0.0195	COPZ2/FOLR1/HLA-C/HLA-DRB4/SEC24A/TMED1/HLA-F/HLA-G/HLA-A/KDELR3/SERPINA1/ZDHHC17/YIF1A/TMED3/AP1G2/HLA-B/HLA-E/LMAN2/SEC22B/VTI1B/SEC13/F8/ERGIC3/CNIH1/YIPF5/TEX261/SEC16A/AP1S1/SORT1/HLA-DQB1/AFTPH/TMED2/NRGN/TMED9/TMED10/SYNRG/NUCB1/CD59	38
CC	GO:0031970	organelle envelope lumen	22/2684	88/19717	0.002969	0.02549	0.01961	NME4/CHCHD2/SNCA/ARL2/TIMM10/PINK1/NDUFA8/SUOX/BLOC1S1/CMC4/FGR/CAT/NDUFB7/GATM/MYOC/TRAP1/ARL2BP/MICU1/SOD1/CPOX/GOLPH3/STOML2	22
CC	GO:0030133	transport vesicle	73/2684	392/19717	0.003056	0.0255	0.01962	COPZ2/FOLR1/HLA-C/HLA-DRB4/RPH3AL/CPA3/SLC18A2/CRISPLD2/SEC24A/YIPF2/SNCA/ATP6V0D1/HLA-F/HLA-G/HLA-A/SYT11/RAB27A/PCSK1/KDELR3/DMXL2/MCTP1/TMED3/RABEPK/AP1G2/NTF3/HLA-B/HLA-E/SSPN/BIN1/SEC22B/STX10/SEMA4C/PENK/TMEM230/TMEM30A/VTI1B/SEC13/SYT17/VAMP3/CNIH1/PTPRN2/IGF1/SNCAIP/SEC16A/HCRT/VAMP7/AP1S1/SORT1/HLA-DQB1/CPE/SV2B/AP1AR/AFTPH/YIPF3/TMED2/VAMP2/NRGN/TMED9/TMED10/LAMP5/AQP2/SYNRG/APH1B/DEFA5/RAB11B/SYT1/RAB15/SYN1/YIPF1/APH1A/BDNF/TH/CD59	73
CC	GO:0035580	specific granule lumen	17/2684	62/19717	0.003062	0.0255	0.01962	SLPI/RAB27A/DNASE1L1/TIMP2/TOLLIP/GGH/ELANE/NFKB1/QPCT/KPNB1/NEU1/CRISP3/GSDMD/ERP44/CEP290/CYFIP1/CFP	17
CC	GO:0030658	transport vesicle membrane	43/2684	208/19717	0.003072	0.0255	0.01962	FOLR1/HLA-C/HLA-DRB4/RPH3AL/SLC18A2/SEC24A/SNCA/HLA-F/HLA-G/HLA-A/SYT11/DMXL2/MCTP1/AP1G2/HLA-B/HLA-E/SEC22B/STX10/SEMA4C/TMEM30A/VTI1B/SEC13/VAMP3/CNIH1/PTPRN2/SEC16A/VAMP7/AP1S1/HLA-DQB1/CPE/SV2B/AFTPH/TMED2/VAMP2/NRGN/TMED10/LAMP5/AQP2/SYNRG/RAB11B/SYT1/SYN1/CD59	43
CC	GO:0090734	site of DNA damage	19/2684	73/19717	0.003432	0.02817	0.02167	SMC6/PARP3/SMCHD1/ARPC1A/NBN/RFWD3/RPA1/ACTR3/SAMHD1/RPA3/RNF138/SMC5/SETMAR/UBQLN4/RAD50/TIMELESS/ATF2/ACTR2/WDR70	19
CC	GO:0033267	axon part	71/2684	382/19717	0.003623	0.02942	0.02263	PCDH9/SCN1B/MICAL1/SETX/TNFRSF1B/STMN2/SLC18A2/UNC5C/SNCA/SRI/ATP6V0D1/SIGMAR1/GOT1/PRKCB/SYT11/UCHL1/SPOCK1/FGF13/SYNJ1/TPX2/PINK1/TIMP2/NTRK2/BIN1/BLOC1S1/PENK/EXOC7/TRAK1/GDPD5/ANK3/GPER1/GPM6A/HSPB1/AUTS2/DCTN2/NDRG2/KIF5C/POLG/PTPRN2/CRHBP/ANG/KIF4A/TMOD2/MYOC/PTBP2/EPHA4/AP1S1/DYNC1H1/P2RX4/PNOC/SOD1/EXOC3/SPAST/KATNB1/ABI1/HIF1A/USP9X/LAMP5/CTTN/CIB1/TRPV2/CDKL5/CXADR/CYFIP1/KCNQ3/PTK2B/DSCAM/SERPINF1/MYH10/LRIG2/TH	71
CC	GO:0031902	late endosome membrane	30/2684	134/19717	0.003697	0.02969	0.02285	MICALL1/HLA-DRB4/MREG/YIPF2/STOML1/LAMP3/VPS37C/ABHD6/RAB27A/TSPAN15/MMD/PIKFYVE/VTI1B/PLD1/CHMP6/NTRK1/VPS16/CD63/MCOLN3/CHMP2A/TMEM59/VAMP7/SLC11A1/WDR91/LAMTOR2/LAMP5/MCOLN1/CHMP1B/NPC1/YIPF1	30
CC	GO:0042611	MHC protein complex	9/2684	25/19717	0.004133	0.03284	0.02527	HLA-C/HLA-DRB4/HLA-F/HLA-G/HLA-A/HLA-B/HLA-E/HLA-DOB/HLA-DQB1	9
CC	GO:0000922	spindle pole	35/2684	164/19717	0.004183	0.0329	0.02531	CDC25B/RMDN3/BEX4/TOPBP1/NDE1/ASPM/DLGAP5/KIF2A/TPX2/NEDD9/DDX11/SPAG5/CDC14A/KNTC1/PRC1/EML1/PLK2/KIF11/CTDP1/LRMP/CCNB1/DYNC1I1/CDC20/NUBP2/TUBGCP5/AURKB/KATNB1/ALMS1/SMC1A/IKBKG/TACC3/CEP63/TUBGCP2/CENPF/NUP62	35
CC	GO:0055029	nuclear DNA-directed RNA polymerase complex	25/2684	107/19717	0.004266	0.0332	0.02554	ERCC1/WDR61/POLR2J/POLR2I/POLR2L/POLR3C/POLR2E/POLR2F/TADA3/MMS19/SETD5/POLR2C/POLR1B/TAF10/PEX2/GTF2A2/TRRAP/CCNH/TAF9B/POLR2G/TAF7/ERCC2/MNAT1/POLR1C/GTF2H3	25
CC	GO:0032806	carboxy-terminal domain protein kinase complex	8/2684	21/19717	0.004554	0.03507	0.02699	MMS19/CCNT2/CCNH/CCNK/ERCC2/MNAT1/GTF2H3/CDK9	8
CC	GO:0042405	nuclear inclusion body	6/2684	13/19717	0.004603	0.03509	0.027	NBN/NUP153/TPR/RANBP2/NXF1/NUP98	6
CC	GO:0030426	growth cone	36/2684	171/19717	0.004688	0.03537	0.02722	PCDH9/SETX/STMN2/UNC5C/SNCA/SIGMAR1/FGF13/PINK1/TIMP2/EXOC7/TRAK1/GDPD5/GPM6A/AUTS2/DCTN2/NDRG2/KIF5C/ANG/TMOD2/PTBP2/EPHA4/EXOC3/KATNB1/ABI1/USP9X/LAMP5/CTTN/CIB1/TRPV2/CDKL5/CXADR/CYFIP1/PTK2B/DSCAM/MYH10/LRIG2	36
CC	GO:0000428	DNA-directed RNA polymerase complex	25/2684	108/19717	0.004849	0.03622	0.02787	ERCC1/WDR61/POLR2J/POLR2I/POLR2L/POLR3C/POLR2E/POLR2F/TADA3/MMS19/SETD5/POLR2C/POLR1B/TAF10/PEX2/GTF2A2/TRRAP/CCNH/TAF9B/POLR2G/TAF7/ERCC2/MNAT1/POLR1C/GTF2H3	25
CC	GO:0035869	ciliary transition zone	17/2684	66/19717	0.006124	0.0453	0.03485	PCDHB13/CETN2/TCTN1/TMEM231/ARL3/IFT52/TMEM80/BBS4/B9D1/C5orf30/PCM1/IFT140/IQCB1/UNC119B/CEP290/TCTN2/DYNC2LI1	17
CC	GO:0042629	mast cell granule	8/2684	22/19717	0.006315	0.04625	0.03558	AKR1B1/RASGRP1/S100A13/KIT/CXCR2/LAT/PIK3CD/SRGN	8
CC	GO:1902554	serine/threonine protein kinase complex	21/2684	88/19717	0.006491	0.04708	0.03622	CCNA2/UVRAG/CKS1B/CDK4/MMS19/CKS2/CCNT2/CCNB2/CHUK/CCNB1/CCNH/ATG13/CCNK/ERCC2/IKBKG/CDK1/CCND2/CDKN1A/MNAT1/GTF2H3/CDK9	21
CC	GO:0090575	RNA polymerase II transcription factor complex	34/2684	163/19717	0.006798	0.04883	0.03757	CEBPA/ERCC1/SMAD3/TADA3/RUNX3/ING2/RXRA/MMS19/LEF1/PPARG/POU2F1/TAF10/GTF2A2/TRRAP/CCNH/NR1H2/TAF9B/TAF7/SFPQ/HIF1A/TLE3/ERCC2/TCF3/CREB1/TCF7L2/MNAT1/GTF2H3/CEBPB/NR5A2/ATF4/NFYC/HMGA1/DDIT3/NR1D2	34
CC	GO:0150034	distal axon	54/2684	285/19717	0.006907	0.04914	0.03781	PCDH9/MICAL1/SETX/STMN2/SLC18A2/UNC5C/SNCA/SRI/ATP6V0D1/SIGMAR1/GOT1/PRKCB/SYT11/FGF13/SYNJ1/PINK1/TIMP2/NTRK2/PENK/EXOC7/TRAK1/GDPD5/GPER1/GPM6A/AUTS2/DCTN2/NDRG2/KIF5C/POLG/PTPRN2/CRHBP/ANG/TMOD2/PTBP2/EPHA4/AP1S1/P2RX4/PNOC/EXOC3/KATNB1/ABI1/USP9X/LAMP5/CTTN/CIB1/TRPV2/CDKL5/CXADR/CYFIP1/PTK2B/DSCAM/MYH10/LRIG2/TH	54
CC	GO:0062023	collagen-containing extracellular matrix	73/2684	406/19717	0.007327	0.05139	0.03954	KAZALD1/EFEMP1/SFRP1/TPSAB1/PTN/TPSB2/SCARA3/WNT5B/GPC5/CDH2/EFEMP2/ADAMDEC1/ADAM19/LAMC3/CPA3/MGP/MFAP4/FBLN5/THBS4/CLU/SLPI/SERPINA3/SERPINA1/PCOLCE/SERPINA5/LTBP3/TIMP2/SERPINE1/APOE/CTSF/ITIH4/HTRA1/SERPINB6/EFNA5/SPON1/CMA1/PXDN/MXRA5/MXRA7/LAMA5/ELANE/POSTN/COL15A1/AGT/COMP/ANG/HAPLN1/CILP/CD151/MYOC/PDGFB/PRG4/ADAMTS3/COL5A3/COL6A3/LTBP4/MBL2/ANXA7/CTSG/THBS2/FCN1/KRT1/COL4A1/LGALS3/TIMP1/VCAN/ADAMTS8/FBLN1/COL3A1/COL4A2/SERPINF1/PSAP/CFP	73
CC	GO:0005942	phosphatidylinositol 3-kinase complex	9/2684	27/19717	0.007361	0.05139	0.03954	SOCS6/SOCS1/PIK3C2B/PIK3CB/PIK3R5/PIK3CD/PIK3C2G/CISH/PIK3CA	9
CC	GO:0030427	site of polarized growth	36/2684	176/19717	0.007537	0.05213	0.04011	PCDH9/SETX/STMN2/UNC5C/SNCA/SIGMAR1/FGF13/PINK1/TIMP2/EXOC7/TRAK1/GDPD5/GPM6A/AUTS2/DCTN2/NDRG2/KIF5C/ANG/TMOD2/PTBP2/EPHA4/EXOC3/KATNB1/ABI1/USP9X/LAMP5/CTTN/CIB1/TRPV2/CDKL5/CXADR/CYFIP1/PTK2B/DSCAM/MYH10/LRIG2	36
CC	GO:0016324	apical plasma membrane	59/2684	318/19717	0.007757	0.05303	0.0408	NOTCH1/FOLR1/ATP1B1/CDH2/FXYD1/MREG/IGFBP2/SLC7A5/ATP6V0D1/SLC22A4/ASPM/TNIK/RAB27A/SLC29A1/ATP8B1/PTH1R/ADAM17/EGFR/STC1/SLC22A18/ERBB2/FAT1/TMEM30A/PLD1/FZD3/TCIRG1/CD44/SLC2A9/ADRB2/VAMP3/PFKM/CLIC5/PRKCI/RAPGEF6/SIPA1L3/GM2A/SORBS2/MTDH/SLC2A5/ANO1/AMOTL2/ABCB1/EMP2/AQP2/PRKAA1/CIB1/NOD1/UPK1B/IL6R/SLC9A3R2/HIP1R/FZD6/PTPRH/SLC4A7/EXOC1/LCT/SLC1A1/PODXL/ATP2B1	59
CC	GO:0000776	kinetochore	29/2684	135/19717	0.007809	0.05303	0.0408	NDE1/NUP160/SS18L1/DCTN6/DCTN3/TPR/BUB1B/SPAG5/SEC13/KNTC1/NDC80/PPP1R12A/DCTN2/CENPE/CCNB1/DYNC1I1/MIS12/CLASP1/CSNK1A1/AURKB/HJURP/BIRC5/CENPT/NUP43/SMC1A/CENPC/KAT2B/NUP98/CENPF	29
CC	GO:0030880	RNA polymerase complex	25/2684	112/19717	0.007885	0.05307	0.04083	ERCC1/WDR61/POLR2J/POLR2I/POLR2L/POLR3C/POLR2E/POLR2F/TADA3/MMS19/SETD5/POLR2C/POLR1B/TAF10/PEX2/GTF2A2/TRRAP/CCNH/TAF9B/POLR2G/TAF7/ERCC2/MNAT1/POLR1C/GTF2H3	25
CC	GO:0042581	specific granule	33/2684	160/19717	0.008994	0.05917	0.04553	SLC2A3/TNFRSF1B/SLPI/STK10/RAB27A/OLR1/DNASE1L1/ITGAL/TIMP2/TMEM30A/PGRMC1/PLD1/TOLLIP/GGH/CD93/ELANE/NFKB1/CMTM6/QPCT/ATP8A1/SLC2A5/LAMTOR2/KPNB1/NEU1/CRISP3/GSDMD/ERP44/CEP290/CYFIP1/UBR4/ALDH3B1/CFP/CD59	33
CC	GO:0044452	nucleolar part	36/2684	178/19717	0.009024	0.05917	0.04553	CHD1/FAM111A/MALT1/SELENBP1/POLR2L/RAI14/POLR2E/POLR2F/UTP6/NHP2/TAF1D/DDX11/RRP1B/ORC6/HEATR1/FHIT/DDX46/SUPT20H/KLF6/POLR1B/RPAIN/MRPL23/WDR43/TOP1/DEAF1/MTDH/ZNF415/HOXB5/LIPA/PEX14/SMARCA5/FOXJ2/SESN1/POLR1C/IMP3/SIRT7	36
CC	GO:0005775	vacuolar lumen	35/2684	172/19717	0.009031	0.05917	0.04553	FUCA1/LGMN/GPC5/GUSB/SERPINA3/SDC1/CTSA/CTSF/PRDX6/C6orf120/RNASE2/ASAH1/TOLLIP/NAGLU/GGH/MAN2B2/ELANE/HEXA/FTL/GM2A/DYNC1H1/LIPA/NEU1/DNAJC3/GAA/PADI2/CYB5R3/GCA/CTSG/VCAN/SGSH/ACTR2/KERA/PSAP/ARSB	35
CC	GO:0044450	microtubule organizing center part	37/2684	185/19717	0.009815	0.06376	0.04905	CETN2/PARP3/CEP350/CEP135/TUBG2/CBY1/TNKS2/MDM1/KIF2A/IFT52/MPHOSPH9/C2CD3/EXOC7/SPAG5/CEP55/SFI1/ROCK1/BBS4/FGFR1OP/LCK/PLK2/PCM1/HSPA6/CLASP1/NUBP2/TUBGCP5/IQCB1/TOP2A/MZT2B/KIAA0753/KATNB1/ALMS1/CEP290/CEP63/SPICE1/OFD1/TUBGCP2	37
CC	GO:0035097	histone methyltransferase complex	20/2684	86/19717	0.01042	0.06508	0.05007	MTF2/JARID2/KDM5A/SUZ12/CHD8/EZH2/NCOA6/PRMT5/ZNF451/HCFC2/WDR5B/SETD1B/MGA/TAF7/EED/RUVBL2/PRDM4/PRDM10/CXXC1/POGZ	20
CC	GO:0045335	phagocytic vesicle	28/2684	132/19717	0.01049	0.06508	0.05007	TAP1/HLA-C/ATP6V0D1/HLA-F/HLA-G/HLA-A/SYT11/UVRAG/HLA-B/HLA-E/SEC22B/RAB11FIP1/TAPBP/TCIRG1/ELANE/VAMP3/GNLY/RAC2/VAMP7/SLC11A1/TAP2/ATP6V0E2/MCOLN1/RAB20/ITGB5/RAB11B/ATG12/NCF1	28
CC	GO:0005885	Arp2/3 protein complex	5/2684	11/19717	0.01054	0.06508	0.05007	ACTR3B/ARPC1A/ACTR3/ARPC5L/ACTR2	5
CC	GO:0035631	CD40 receptor complex	5/2684	11/19717	0.01054	0.06508	0.05007	TRAF5/BIRC2/CD40/CHUK/TRAF3	5
CC	GO:0033268	node of Ranvier	6/2684	15/19717	0.01054	0.06508	0.05007	SCN1B/SPOCK1/BIN1/ANK3/MYOC/KCNQ3	6
CC	GO:0099059	integral component of presynaptic active zone membrane	6/2684	15/19717	0.01054	0.06508	0.05007	CDH2/SYT11/GPM6A/ATP2B4/CACNA1D/ATP2B1	6
CC	GO:0044455	mitochondrial membrane part	44/2684	229/19717	0.01077	0.06593	0.05072	COX7A1/NDUFC1/FIS1/SLC25A4/SDHC/NDUFA13/NDUFS4/MPC2/NDUFA4L2/TIMM10/NDUFB4/PINK1/NDUFA4/UQCR10/NDUFA8/TMEM11/SCO2/APOO/COQ6/CYC1/NDUFA2/COX6A1/NDUFB6/NDUFB7/SDHD/ANKZF1/NDUFB2/NDUFA6/NDUFA10/COA3/NDUFB11/MICU1/NDUFB8/NDUFA3/UQCRQ/NDUFS3/NDUFS7/SFXN1/COQ2/NDUFS6/SAMM50/MPC1/NDUFA1/UQCRC1	44
CC	GO:0000775	chromosome, centromeric region	38/2684	193/19717	0.01153	0.07002	0.05388	ZNF330/NDE1/DNMT1/NUP160/SS18L1/UVRAG/DCTN6/DCTN3/TPR/BUB1B/SPAG5/SEC13/CDCA8/KNTC1/NDC80/PPP1R12A/DCTN2/DAXX/CENPE/CCNB1/NCAPG/DYNC1I1/MIS12/CLASP1/ATRX/CSNK1A1/AURKB/HJURP/BIRC5/CENPT/NUP43/SMC1A/SUV39H2/CENPC/KAT2B/CEBPB/NUP98/CENPF	38
CC	GO:0070603	SWI/SNF superfamily-type complex	18/2684	76/19717	0.01211	0.07247	0.05576	BAZ1A/SUZ12/SS18L1/SMARCD3/ZNHIT1/ARID1A/GATAD2A/TRRAP/EN1/PBRM1/CHD3/RUVBL2/KAT5/SMARCA5/HDAC1/SMARCD2/BPTF/HMGXB4	18
CC	GO:0071556	integral component of lumenal side of endoplasmic reticulum membrane	9/2684	29/19717	0.01222	0.07247	0.05576	HLA-C/HLA-DRB4/HLA-F/HLA-G/HLA-A/HLA-B/HLA-E/TAPBP/HLA-DQB1	9
CC	GO:0098553	lumenal side of endoplasmic reticulum membrane	9/2684	29/19717	0.01222	0.07247	0.05576	HLA-C/HLA-DRB4/HLA-F/HLA-G/HLA-A/HLA-B/HLA-E/TAPBP/HLA-DQB1	9
CC	GO:0031904	endosome lumen	10/2684	34/19717	0.01261	0.07255	0.05582	LGMN/JAK2/LRPAP1/PRF1/PDLIM4/CD63/AP4S1/LNPEP/AP4M1/SFTPC	10
CC	GO:0051233	spindle midzone	10/2684	34/19717	0.01261	0.07255	0.05582	RACGAP1/MAPRE3/CDCA8/KIF18B/EML1/CENPE/CTDP1/AURKB/CTTN/MAPRE2	10
CC	GO:0098636	protein complex involved in cell adhesion	10/2684	34/19717	0.01261	0.07255	0.05582	ITGBL1/ITGAX/CTLA4/ITGAL/ITGA5/ITGAE/CD28/ITGB7/ITGB5/TSPAN32	10
CC	GO:0032994	protein-lipid complex	11/2684	39/19717	0.01264	0.07255	0.05582	LIPC/CLU/APOM/APOL1/APOE/BIN1/APOO/PLA2G7/APOC1/LPL/LSR	11
CC	GO:0016234	inclusion body	19/2684	82/19717	0.01282	0.07255	0.05582	TBK1/SNCA/CLU/NBN/HERPUD1/SYNE2/NUP153/PRNP/ZDHHC17/PINK1/TPR/GPX1/FGR/RANBP2/NXF1/PRKCQ/EDEM1/ATF4/NUP98	19
CC	GO:0031252	cell leading edge	71/2684	403/19717	0.01282	0.07255	0.05582	DYSF/IQGAP2/PLEKHO1/CDH2/LCP1/STMN2/UNC5C/SH2B2/GABARAPL1/KLHL2/MACF1/SYNE2/ADAM17/MTMR9/ITGA5/BAIAP2/ACTR3/NEDD9/INSR/SH3YL1/FAT1/ARHGEF2/MTMR6/PDLIM4/GABRA4/ROCK1/PLEKHA1/FGR/GPER1/CXCR4/CD44/FERMT2/ARAP3/SNX2/DGKZ/ARHGEF7/WIPF1/WLS/PRKCI/RAB13/RAC2/VAMP7/SORBS2/PLXND1/FERMT1/SLC39A14/PTPRK/PHACTR4/ABI1/LAMP5/NF2/PARVB/TLN2/CTTN/CIB1/CDKL5/HIP1R/EPS8L2/INPP5E/CYFIP1/RASGRP2/LIMA1/ACTN1/PTK2B/ATF4/ACTR2/MYH10/PODXL/ATP2B1/GDPD2/PIK3CA	71
CC	GO:0045177	apical part of cell	68/2684	384/19717	0.01309	0.07298	0.05615	NOTCH1/FOLR1/ATP1B1/LGMN/CDH2/FXYD1/MREG/IGFBP2/SLC7A5/ATP6V0D1/SLC22A4/ASPM/TNIK/RAB27A/SLC29A1/ATP8B1/PTH1R/ADAM17/EGFR/STC1/SLC22A18/HFE/ERBB2/FAT1/TMEM30A/PLD1/FZD3/TCIRG1/CD44/SLC2A9/ADRB2/VAMP3/PFKM/CLIC5/PCM1/PRKCI/RAPGEF6/VAMP7/SIPA1L3/GM2A/SORBS2/MTDH/CA2/SLC2A5/ANO1/AMOTL2/ABCB1/SNX10/SRR/EMP2/AQP2/PRKAA1/NF2/CIB1/NOD1/UPK1B/IL6R/SLC9A3R2/HIP1R/FZD6/PTPRH/SLC4A7/EXOC1/LCT/SLC1A1/PODXL/ATP2B1/DYNC2LI1	68
CC	GO:0034361	very-low-density lipoprotein particle	7/2684	20/19717	0.01319	0.07298	0.05615	APOM/APOL1/APOE/APOO/APOC1/LPL/LSR	7
CC	GO:0034385	triglyceride-rich plasma lipoprotein particle	7/2684	20/19717	0.01319	0.07298	0.05615	APOM/APOL1/APOE/APOO/APOC1/LPL/LSR	7
CC	GO:0044798	nuclear transcription factor complex	39/2684	201/19717	0.0134	0.07358	0.05661	CEBPA/SOX9/ERCC1/SMAD3/BRF2/TADA3/RUNX3/TAF1D/ING2/RXRA/MMS19/LEF1/PPARG/POU2F1/TAF10/GTF2A2/TRRAP/CCNH/NR1H2/TAF9B/TAF7/SFPQ/HIF1A/TLE3/ERCC2/PTOV1/TCF3/CREB1/TCF7L2/MNAT1/GTF2H3/CEBPB/NR5A2/ATF4/NFYC/HMGA1/GTF3C5/DDIT3/NR1D2	39
CC	GO:0000779	condensed chromosome, centromeric region	25/2684	118/19717	0.0152	0.0829	0.06378	NDE1/SS18L1/DCTN6/DCTN3/BUB1B/SPAG5/KNTC1/NDC80/CENPE/CCNB1/NCAPG/DYNC1I1/MIS12/CLASP1/ATRX/CSNK1A1/AURKB/HJURP/BIRC5/CENPT/NUP43/SMC1A/CENPC/CEBPB/CENPF	25
CC	GO:0002102	podosome	9/2684	30/19717	0.0154	0.08336	0.06414	LCP1/SH3GL1/ASAP1/ARHGEF2/HNRNPK/SCIN/CTTN/ACTR2/LPXN	9
CC	GO:0042383	sarcolemma	28/2684	136/19717	0.01555	0.08357	0.0643	SGCA/DYSF/SCN1B/ATP1B1/CDH2/SNTA1/FXYD1/SGCG/PEMT/SRI/SGCB/RTN2/SLC27A6/SLC38A2/BSG/SSPN/BIN1/KCNJ2/ANK3/SLC2A5/ABCC8/PPP3CA/CACNB2/COL6A3/ATP2B4/CIB1/CACNA1D/SNTB1	28
CC	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex	5/2684	12/19717	0.01607	0.08405	0.06467	CCNT2/CCNH/CCNK/MNAT1/CDK9	5
CC	GO:0044615	nuclear pore nuclear basket	5/2684	12/19717	0.01607	0.08405	0.06467	CETN2/NUP153/TPR/RANBP2/NUP98	5
CC	GO:0001725	stress fiber	16/2684	67/19717	0.01609	0.08405	0.06467	LCP1/SH2B2/TRIP6/MICALL2/PDLIM1/LIMCH1/PDLIM4/PDLIM2/LPP/NEBL/FERMT2/SIPA1L3/LIMA1/ACTN1/MYH10/SORBS1	16
CC	GO:0097517	contractile actin filament bundle	16/2684	67/19717	0.01609	0.08405	0.06467	LCP1/SH2B2/TRIP6/MICALL2/PDLIM1/LIMCH1/PDLIM4/PDLIM2/LPP/NEBL/FERMT2/SIPA1L3/LIMA1/ACTN1/MYH10/SORBS1	16
CC	GO:0034399	nuclear periphery	27/2684	131/19717	0.01704	0.08841	0.06802	SRPK1/JAK2/HNRNPA2B1/ATXN7/PRR14/NUP153/THOC1/TPR/CSNK2B/LMNB1/NARF/KIF4A/PML/SATB1/SFPQ/RUVBL2/AKAP8/SMC1A/CXXC1/EIF6/CEBPB/ATF4/ARFGEF1/NUP98/CENPF/SATB2/SORBS1	27
CC	GO:0030027	lamellipodium	37/2684	193/19717	0.01874	0.09596	0.07383	DYSF/IQGAP2/CDH2/STMN2/UNC5C/KLHL2/SYNE2/ACTR3/NEDD9/FAT1/PDLIM4/ROCK1/CD44/FERMT2/ARAP3/SNX2/DGKZ/ARHGEF7/RAB13/RAC2/VAMP7/SORBS2/PLXND1/SLC39A14/PHACTR4/ABI1/NF2/PARVB/CTTN/CIB1/CYFIP1/PTK2B/ACTR2/MYH10/PODXL/GDPD2/PIK3CA	37
CC	GO:0000780	condensed nuclear chromosome, centromeric region	8/2684	26/19717	0.01875	0.09596	0.07383	SS18L1/BUB1B/NDC80/CCNB1/MIS12/ATRX/AURKB/CENPC	8
CC	GO:0035578	azurophil granule lumen	20/2684	91/19717	0.01915	0.09699	0.07462	FUCA1/GUSB/SERPINA3/CTSA/PRDX6/C6orf120/RNASE2/TOLLIP/GGH/ELANE/FTL/GM2A/DYNC1H1/DNAJC3/PADI2/CYB5R3/GCA/CTSG/ACTR2/ARSB	20
CC	GO:0036464	cytoplasmic ribonucleoprotein granule	40/2684	212/19717	0.01922	0.09699	0.07462	CIRBP/LSM4/BARD1/USP3/PUM2/APOBEC3C/SOCS1/LSM3/HNRNPK/EID1/PSMC2/ROCK1/GABPB1/RC3H2/PABPC3/BTBD2/DCP2/SHB/TIA1/TRIM21/SNCAIP/LARP4/PSMC3/DYNC1I1/POLR2G/TOP1/KPNB1/DDX1/AGO3/YBX1/TARDBP/CTSG/HELZ/EDC4/GHR/PIWIL2/CDK9/STAU1/LSM2/RPLP0	40
CC	GO:0031519	PcG protein complex	12/2684	47/19717	0.02091	0.1049	0.08067	MTF2/JARID2/SUZ12/SKP1/EZH2/CSNK2B/PCGF1/ASXL2/CBX7/EED/RYBP/RING1	12
CC	GO:0035577	azurophil granule membrane	14/2684	58/19717	0.02142	0.1067	0.08208	TMEM30A/CMTM6/CD63/LRMP/VAMP7/ATP8A1/DDOST/ATP11B/GAA/VNN1/RAP1B/VAPA/PSAP/DNAJC13	14
CC	GO:0032432	actin filament bundle	17/2684	75/19717	0.02205	0.1091	0.08391	LCP1/SH2B2/TRIP6/MICALL2/PDLIM1/LIMCH1/PDLIM4/PDLIM2/LPP/NEBL/CRYAB/FERMT2/SIPA1L3/LIMA1/ACTN1/MYH10/SORBS1	17
CC	GO:0031985	Golgi cisterna	24/2684	116/19717	0.02248	0.1099	0.08452	GAL3ST4/YIPF2/B4GALT2/NECAB3/TMED3/FUT1/GOLGA8A/ST3GAL2/B4GALT7/TMEM59/PSENEN/SORT1/GALNT3/FUT8/TMED2/SGMS1/INPP5E/GOLPH3/ABO/NUCB1/FUT4/YIPF1/APH1A/B4GALT3	24
CC	GO:0034358	plasma lipoprotein particle	10/2684	37/19717	0.02292	0.1099	0.08452	LIPC/CLU/APOM/APOL1/APOE/APOO/PLA2G7/APOC1/LPL/LSR	10
CC	GO:1990777	lipoprotein particle	10/2684	37/19717	0.02292	0.1099	0.08452	LIPC/CLU/APOM/APOL1/APOE/APOO/PLA2G7/APOC1/LPL/LSR	10
CC	GO:0005675	transcription factor TFIIH holo complex	5/2684	13/19717	0.02324	0.1099	0.08452	MMS19/CCNH/ERCC2/MNAT1/GTF2H3	5
CC	GO:0005736	RNA polymerase I complex	5/2684	13/19717	0.02324	0.1099	0.08452	POLR2L/POLR2E/POLR2F/POLR1B/POLR1C	5
CC	GO:0036038	MKS complex	5/2684	13/19717	0.02324	0.1099	0.08452	TCTN1/TMEM231/B9D1/CEP290/TCTN2	5
CC	GO:1990023	mitotic spindle midzone	5/2684	13/19717	0.02324	0.1099	0.08452	KIF18B/EML1/CENPE/AURKB/CTTN	5
CC	GO:0032839	dendrite cytoplasm	9/2684	32/19717	0.0235	0.1104	0.08496	GABARAPL1/BAIAP2/ADA/KIF5C/WLS/SFPQ/SOD1/CDKL5/HIP1R	9
CC	GO:0005681	spliceosomal complex	35/2684	185/19717	0.02609	0.1218	0.09373	RBM28/ADAR/HNRNPA2B1/CIRBP/HTATSF1/LSM4/SNRNP40/SF3B1/ZMAT5/SNRNP25/PRPF4B/LSM3/AKAP17A/CWF19L1/HNRNPK/DDX23/SF3B5/LSM5/PTBP2/BUD31/HNRNPA1/ZCCHC8/PPIE/SNIP1/SNRPD2/YBX1/SREK1/TXNL4A/RBM41/DDX41/LGALS3/LUC7L/GEMIN2/PPIH/LSM2	35
CC	GO:0035770	ribonucleoprotein granule	41/2684	223/19717	0.02661	0.1235	0.09499	CIRBP/LSM4/BARD1/USP3/PUM2/APOBEC3C/SOCS1/LSM3/HNRNPK/EID1/PSMC2/ROCK1/GABPB1/RC3H2/PABPC3/BTBD2/DCP2/SHB/TIA1/TRIM21/SNCAIP/LARP4/PSMC3/DYNC1I1/POLR2G/TOP1/YTHDC2/KPNB1/DDX1/AGO3/YBX1/TARDBP/CTSG/HELZ/EDC4/GHR/PIWIL2/CDK9/STAU1/LSM2/RPLP0	41
CC	GO:0005795	Golgi stack	29/2684	149/19717	0.02857	0.1318	0.1014	TOM1L1/GAL3ST4/YIPF2/B4GALT2/NECAB3/TMED3/FUT1/GOLGA8A/ST3GAL2/MBTPS1/B4GALT7/TMEM59/RASIP1/PSENEN/SORT1/GALNT3/FUT8/TMED2/GOLGB1/SGMS1/AKAP9/INPP5E/GOLPH3/ABO/NUCB1/FUT4/YIPF1/APH1A/B4GALT3	29
CC	GO:0005643	nuclear pore	19/2684	89/19717	0.0292	0.1338	0.103	CETN2/NUP160/NUP153/NPAP1/TPR/NUP50/SEC13/RANBP2/NXF1/SNUPN/NUP210/KPNB1/NUP43/NDC1/KPNA1/MVP/KPNA3/NUP98/NUP62	19
CC	GO:0043202	lysosomal lumen	20/2684	95/19717	0.02955	0.1346	0.1035	FUCA1/LGMN/GPC5/GUSB/SDC1/CTSA/CTSF/ASAH1/NAGLU/MAN2B2/HEXA/GM2A/LIPA/NEU1/GAA/VCAN/SGSH/KERA/PSAP/ARSB	20
CC	GO:1904949	ATPase complex	21/2684	101/19717	0.02976	0.1347	0.1037	BAZ1A/ATP1B1/FXYD1/SUZ12/SS18L1/SMARCD3/ZNHIT1/ARID1A/GATAD2A/TRRAP/EN1/ABCA2/PBRM1/CHD3/RUVBL2/KAT5/SMARCA5/HDAC1/SMARCD2/BPTF/HMGXB4	21
CC	GO:0005788	endoplasmic reticulum lumen	54/2684	309/19717	0.03098	0.1393	0.1072	WNT5B/CDH2/LIPC/IGFBP5/CLU/EOGT/TSPAN15/LRPAP1/SERPINA1/SIL1/APOL1/CES2/APOE/APLP2/IGFBP4/RCN1/BMP4/PENK/SPON1/RCN3/STS/ESD/F8/CRTAP/CLN6/CES3/MZB1/COL15A1/MBTPS1/PTPRN2/MXRA8/IL6/CHRDL1/PDGFB/FKBP10/SCG2/CP/COL5A3/COL6A3/DNAJC3/ERP44/PPIB/ARSF/COL4A1/TIMP1/VCAN/COL3A1/NUCB1/RCN2/COL4A2/HSPA5/STC2/CFP/ARSB	54
CC	GO:0044306	neuron projection terminus	27/2684	138/19717	0.03175	0.1393	0.1072	SCRG1/GCH1/MICAL1/SLC18A2/SNCA/SRI/ATP6V0D1/GOT1/PRKCB/SYT11/UCHL1/SYNJ1/BAIAP2/NTRK2/PENK/GPER1/POLG/PTPRN2/CRHBP/EPHA4/AP1S1/P2RX4/PNOC/VAMP2/SYT1/CYFIP1/TH	27
CC	GO:0001650	fibrillar center	26/2684	132/19717	0.03209	0.1393	0.1072	CHD1/FAM111A/MALT1/SELENBP1/RAI14/POLR2F/DDX11/ORC6/HEATR1/FHIT/DDX46/SUPT20H/KLF6/RPAIN/MRPL23/WDR43/TOP1/DEAF1/MTDH/ZNF415/HOXB5/LIPA/PEX14/SMARCA5/FOXJ2/SESN1	26
CC	GO:0031588	nucleotide-activated protein kinase complex	5/2684	14/19717	0.03218	0.1393	0.1072	SIK1/PRKAR2A/PRKAG1/PRKAB1/PRKAA1	5
CC	GO:0033276	transcription factor TFTC complex	5/2684	14/19717	0.03218	0.1393	0.1072	TADA3/TAF10/TRRAP/TAF9B/TAF7	5
CC	GO:0034362	low-density lipoprotein particle	5/2684	14/19717	0.03218	0.1393	0.1072	APOM/APOE/APOO/PLA2G7/LSR	5
CC	GO:0061702	inflammasome complex	5/2684	14/19717	0.03218	0.1393	0.1072	AIM2/NLRP1/CARD8/CASP4/GSDMD	5
CC	GO:0101003	ficolin-1-rich granule membrane	14/2684	61/19717	0.03226	0.1393	0.1072	SLC2A3/NBEAL2/LILRB2/ITGAX/SERPINB6/TCIRG1/CD93/CR1/PTPRN2/SLC11A1/CD58/GAA/LGALS3/UBR4	14
CC	GO:0031301	integral component of organelle membrane	39/2684	214/19717	0.03389	0.1445	0.1112	SLC22A17/FIS1/LBR/VOPP1/SLC25A4/SYT11/MPC2/ENTPD4/PINK1/YIF1A/TPST1/SLC35A2/TMEM11/SCO2/PCSK7/STX10/APOO/RFNG/PEX11A/ERGIC3/VAMP3/PEX2/PTPRN2/MAN1C1/TEX261/VAMP7/COA3/P2RX4/PEX12/MICU1/SGMS1/FAR2/SFXN1/SYT1/COQ2/MPC1/NPC1/UNC50/CHST12	39
CC	GO:0005874	microtubule	70/2684	416/19717	0.03414	0.1445	0.1112	RMDN3/BEX4/DYSF/TUBG2/DNAL4/ARL3/GABARAPL1/NDE1/MACF1/ASPM/HAUS3/MDM1/FGF13/TUBB2B/MAP7/HSPH1/KIF2A/MAP3K11/SYNJ1/TPX2/BAIAP2/RACGAP1/DCTN3/DYNLRB1/HAUS2/MAPRE3/NUSAP1/SPAG5/ARHGEF2/TTLL4/TTLL1/KNTC1/KIF18B/PRC1/DCTN2/EML1/TUBA4A/KIF5C/CENPE/KIF11/CRHBP/TUBB6/DYNC1I1/KIF4A/TPGS2/CLASP1/KIF15/TUBGCP5/AURKB/EIF3A/DYNC1H1/PARP4/CCDC181/BIRC5/MTUS2/SPAST/KATNB1/CYLD/HOOK2/GTSE1/CDK1/TUBB2A/BCL10/MAPRE2/EML4/STAU2/KIF20A/TUBGCP2/GABARAP/DYNC2LI1	70
CC	GO:0070069	cytochrome complex	9/2684	34/19717	0.03426	0.1445	0.1112	NDUFA4L2/NDUFA4/UQCR10/CYC1/COX8A/COX6A1/COA3/UQCRQ/UQCRC1	9
CC	GO:0005814	centriole	27/2684	139/19717	0.03447	0.1445	0.1112	CETN2/PARP3/CEP350/CEP135/CBY1/MDM1/KIF2A/IFT52/MPHOSPH9/C2CD3/CEP55/SFI1/ROCK1/BBS4/FGFR1OP/PLK2/PCM1/HSPA6/NUBP2/IQCB1/TOP2A/KIAA0753/ALMS1/CEP290/CEP63/SPICE1/OFD1	27
CC	GO:0070820	tertiary granule	31/2684	164/19717	0.03496	0.1445	0.1112	SLC2A3/NBEAL2/LILRB2/OLR1/ITGAX/PGM1/TIMP2/RAP2C/SERPINB6/ASAH1/PLD1/GGH/TCIRG1/CD93/CR1/QPCT/PTPRN2/SLC11A1/LAMTOR2/CD58/HBB/CRISP3/GAA/GSDMD/ALDOC/LGALS3/CYFIP1/UBR4/CFP/NRAS/CD59	31
CC	GO:0042641	actomyosin	17/2684	79/19717	0.03517	0.1445	0.1112	LCP1/SH2B2/TRIP6/MICALL2/PDLIM1/LIMCH1/PDLIM4/PDLIM2/LPP/NEBL/FERMT2/SIPA1L3/KAT2B/LIMA1/ACTN1/MYH10/SORBS1	17
CC	GO:0016010	dystrophin-associated glycoprotein complex	6/2684	19/19717	0.03542	0.1445	0.1112	SGCA/SNTA1/SGCG/SGCB/SSPN/SNTB1	6
CC	GO:0031362	anchored component of external side of plasma membrane	6/2684	19/19717	0.03542	0.1445	0.1112	FOLR1/PRNP/EFNA5/FOLR2/PRND/CD59	6
CC	GO:0090665	glycoprotein complex	6/2684	19/19717	0.03542	0.1445	0.1112	SGCA/SNTA1/SGCG/SGCB/SSPN/SNTB1	6
CC	GO:0098945	intrinsic component of presynaptic active zone membrane	6/2684	19/19717	0.03542	0.1445	0.1112	CDH2/SYT11/GPM6A/ATP2B4/CACNA1D/ATP2B1	6
CC	GO:0030131	clathrin adaptor complex	8/2684	29/19717	0.0356	0.1445	0.1112	AP1B1/AP1G2/AP2M1/AP1S1/AFTPH/SYNRG/HIP1R/AP4M1	8
CC	GO:0005875	microtubule associated complex	29/2684	152/19717	0.0362	0.1455	0.1119	DNAL4/NDE1/HAUS3/MAP7/KIF2A/DCTN6/DCTN3/TPR/DYNLRB1/HAUS2/PEA15/CDCA8/KIF18B/DCTN2/EML1/KIF5C/CENPE/KIF11/DYNC1I1/KIF4A/KIF15/AURKB/DYNC1H1/BIRC5/KATNB1/KIF20A/GABARAP/STAU1/DYNC2LI1	29
CC	GO:0031010	ISWI-type complex	4/2684	10/19717	0.03641	0.1455	0.1119	BAZ1A/SMARCA5/BPTF/HMGXB4	4
CC	GO:0031080	nuclear pore outer ring	4/2684	10/19717	0.03641	0.1455	0.1119	NUP160/SEC13/NUP43/NUP98	4
CC	GO:0032153	cell division site	15/2684	68/19717	0.03778	0.1501	0.1155	ECT2/NDE1/RACGAP1/DCTN3/RALA/RHOF/CEP55/RND2/TUBGCP5/NF2/CENPC/LIMA1/KIF20A/TUBGCP2/MYH10	15
CC	GO:0043195	terminal bouton	12/2684	51/19717	0.03812	0.1507	0.1159	MICAL1/SLC18A2/SNCA/SYT11/SYNJ1/NTRK2/POLG/PTPRN2/AP1S1/P2RX4/CYFIP1/TH	12
CC	GO:0001726	ruffle	32/2684	172/19717	0.03962	0.1554	0.1196	PLEKHO1/LCP1/SH2B2/KLHL2/MACF1/ADAM17/MTMR9/ITGA5/BAIAP2/SH3YL1/ARHGEF2/MTMR6/ROCK1/PLEKHA1/FGR/ARAP3/ARHGEF7/WIPF1/FERMT1/NF2/TLN2/CTTN/CIB1/CDKL5/HIP1R/EPS8L2/INPP5E/CYFIP1/RASGRP2/LIMA1/ACTN1/PODXL	32
CC	GO:0032580	Golgi cisterna membrane	19/2684	92/19717	0.03974	0.1554	0.1196	GAL3ST4/B4GALT2/TMED3/FUT1/GOLGA8A/ST3GAL2/B4GALT7/PSENEN/SORT1/GALNT3/FUT8/TMED2/INPP5E/GOLPH3/ABO/NUCB1/FUT4/APH1A/B4GALT3	19
CC	GO:0031300	intrinsic component of organelle membrane	42/2684	237/19717	0.04276	0.1622	0.1248	SLC22A17/MREG/FIS1/LBR/VOPP1/SLC25A4/SYT11/MPC2/ENTPD4/PINK1/YIF1A/TPST1/SLC35A2/TMEM11/SCO2/PCSK7/STX10/APOO/RFNG/PEX11A/ERGIC3/VAMP3/PEX2/PTPRN2/MAN1C1/TEX261/VAMP7/COA3/P2RX4/PEX12/MICU1/SGMS1/RAB11B/FAR2/SFXN1/SYT1/COQ2/SYN1/MPC1/NPC1/UNC50/CHST12	42
CC	GO:0034451	centriolar satellite	8/2684	30/19717	0.04294	0.1622	0.1248	C2CD3/EXOC7/SPAG5/BBS4/PCM1/KIAA0753/CEP290/OFD1	8
CC	GO:0000778	condensed nuclear chromosome kinetochore	5/2684	15/19717	0.043	0.1622	0.1248	BUB1B/NDC80/CCNB1/MIS12/CENPC	5
CC	GO:0005779	integral component of peroxisomal membrane	5/2684	15/19717	0.043	0.1622	0.1248	FIS1/PEX11A/PEX2/PEX12/FAR2	5
CC	GO:0012510	trans-Golgi network transport vesicle membrane	5/2684	15/19717	0.043	0.1622	0.1248	AP1G2/AP1S1/AFTPH/NRGN/SYNRG	5
CC	GO:0031231	intrinsic component of peroxisomal membrane	5/2684	15/19717	0.043	0.1622	0.1248	FIS1/PEX11A/PEX2/PEX12/FAR2	5
CC	GO:0045120	pronucleus	5/2684	15/19717	0.043	0.1622	0.1248	CCNA2/EZH2/EED/AKAP8/CENPF	5
CC	GO:0000777	condensed chromosome kinetochore	21/2684	105/19717	0.04346	0.1631	0.1255	NDE1/SS18L1/DCTN6/DCTN3/BUB1B/SPAG5/KNTC1/NDC80/CENPE/CCNB1/DYNC1I1/MIS12/CLASP1/CSNK1A1/HJURP/BIRC5/CENPT/NUP43/SMC1A/CENPC/CENPF	21
CC	GO:0000794	condensed nuclear chromosome	20/2684	99/19717	0.04369	0.1632	0.1256	TOPBP1/CHEK1/SS18L1/UBE2I/BUB1B/NCAPH/NDC80/CCNB1/MIS12/BRCA2/ATRX/AURKB/RAD50/RAD1/AGO3/SMC1A/RAD9A/CENPC/HSPA2/SYN1	20
CC	GO:0000790	nuclear chromatin	63/2684	377/19717	0.04787	0.1779	0.1369	BAZ1A/AR/STAT1/IRF1/SUZ12/NIPBL/SMAD3/KLHDC3/FOXC1/NCOA3/TCF7/SS18L1/EZH2/SMARCD3/USP3/RUNX3/ING2/RXRA/DDX11/HNRNPK/ZNHIT1/ARID1A/GATAD2A/HMGB3/ASXL2/TRRAP/NASP/CBX7/MYC/EN1/ATRX/BUD31/TRIM24/SATB1/EED/PBRM1/HMGB1/RAD50/MCMBP/CHD3/RUVBL2/KAT6A/KAT5/NCOR1/HIF1A/SMARCA5/HDAC1/TIMELESS/SMARCD2/TARDBP/DFFB/BPTF/TCF3/CREB1/TCF7L2/CENPC/RING1/CDK9/CEBPB/MORF4L1/SIRT7/HMGXB4/POGZ	63
CC	GO:0034708	methyltransferase complex	22/2684	113/19717	0.05116	0.1857	0.1429	MTF2/JARID2/KDM5A/SUZ12/CHD8/EZH2/NCOA6/PRMT5/ZNF451/RBM15/HCFC2/WDR5B/SETD1B/MGA/TAF7/EED/RUVBL2/SNRPD2/PRDM4/PRDM10/CXXC1/POGZ	22
CC	GO:0005652	nuclear lamina	4/2684	11/19717	0.0512	0.1857	0.1429	PRR14/LMNB1/NARF/EIF6	4
CC	GO:0031094	platelet dense tubular network	4/2684	11/19717	0.0512	0.1857	0.1429	ATP2A3/SERPINA5/F2R/ITPR2	4
CC	GO:0008305	integrin complex	8/2684	31/19717	0.05122	0.1857	0.1429	ITGBL1/ITGAX/ITGAL/ITGA5/ITGAE/ITGB7/ITGB5/TSPAN32	8
CC	GO:0030140	trans-Golgi network transport vesicle	8/2684	31/19717	0.05122	0.1857	0.1429	AP1G2/AP1S1/SORT1/AFTPH/NRGN/TMED9/TMED10/SYNRG	8
CC	GO:0031248	protein acetyltransferase complex	19/2684	95/19717	0.05281	0.1896	0.1459	TADA3/MSL3/MSL2/SUPT20H/TAF10/NAA16/BRPF1/TRRAP/NAA50/TAF9B/TAF7/RUVBL2/KAT6A/KAT5/YEATS2/OGT/KAT2B/EP300/MORF4L1	19
CC	GO:1902493	acetyltransferase complex	19/2684	95/19717	0.05281	0.1896	0.1459	TADA3/MSL3/MSL2/SUPT20H/TAF10/NAA16/BRPF1/TRRAP/NAA50/TAF9B/TAF7/RUVBL2/KAT6A/KAT5/YEATS2/OGT/KAT2B/EP300/MORF4L1	19
CC	GO:1905368	peptidase complex	18/2684	89/19717	0.05312	0.1896	0.1459	PSMB9/TADA3/IDE/PSMC2/SUPT20H/SPCS3/HSPB1/SEC11A/PSMB6/TRRAP/PSMC3/TAF9B/PSMD8/UBQLN4/PSMB5/PSMD10/PAAF1/USP14	18
CC	GO:0031256	leading edge membrane	31/2684	170/19717	0.0533	0.1896	0.1459	PLEKHO1/LCP1/GABARAPL1/MACF1/SYNE2/ADAM17/MTMR9/ITGA5/INSR/SH3YL1/ARHGEF2/MTMR6/GABRA4/PLEKHA1/FGR/GPER1/CD44/FERMT2/WLS/PLXND1/FERMT1/PTPRK/LAMP5/NF2/CIB1/CDKL5/HIP1R/EPS8L2/RASGRP2/ATF4/ATP2B1	31
CC	GO:0034364	high-density lipoprotein particle	7/2684	26/19717	0.05404	0.1913	0.1472	LIPC/CLU/APOM/APOL1/APOE/APOO/APOC1	7
CC	GO:0030479	actin cortical patch	5/2684	16/19717	0.05575	0.1946	0.1497	ACTR3/CAPZA1/WIPF1/HIP1R/ACTR2	5
CC	GO:0035098	ESC/E(Z) complex	5/2684	16/19717	0.05575	0.1946	0.1497	MTF2/JARID2/SUZ12/EZH2/EED	5
CC	GO:0061645	endocytic patch	5/2684	16/19717	0.05575	0.1946	0.1497	ACTR3/CAPZA1/WIPF1/HIP1R/ACTR2	5
CC	GO:0019867	outer membrane	36/2684	203/19717	0.05655	0.1965	0.1512	LTC4S/RMDN3/FIS1/VPS13C/BPHL/SNCA/SIGMAR1/ANKH/SNN/CLMN/ARMCX2/BCL2A1/SYNE2/BAD/AGPAT5/PINK1/ACSL5/GK/ASS1/ANKZF1/TSPO/ARMCX1/MYOC/EPHA4/UBB/DHCR7/MCL1/ARMCX6/BCL2L2/CYB5R3/RAF1/VDAC3/ATF2/SAMM50/LPIN1/STARD7	36
CC	GO:0120111	neuron projection cytoplasm	17/2684	84/19717	0.05865	0.2028	0.1561	GABARAPL1/UCHL1/BAIAP2/ADA/BLOC1S1/TRAK1/HSPB1/KIF5C/WLS/KIF4A/DYNC1H1/SFPQ/SOD1/SPAST/HIF1A/CDKL5/HIP1R	17
CC	GO:0016323	basolateral plasma membrane	38/2684	217/19717	0.06011	0.2069	0.1592	FOLR1/ATP1B1/CDH2/ENPP1/TFRC/KCNQ1/SLC29A1/CD38/PTH1R/MAP7/ABCC4/EGFR/SLC27A5/IDE/ERBB2/HPGD/ANK3/SLC7A6/ARRB1/CD44/SLC2A9/CD81/CLCA2/LIN7B/ABCC1/GM2A/PDGFB/CA2/NOD2/NAIP/AQP2/ATP2B4/NOD1/IL6R/CXADR/ERBB4/SLC4A7/ATP2B1	38
CC	GO:0044853	plasma membrane raft	21/2684	109/19717	0.06124	0.2098	0.1614	ATP1B1/CDH2/JAK2/FXYD1/MAPK3/PRKAR2A/CD8A/INSR/EFNA5/PLVAP/SELE/TFPI/F2R/CHRNA3/NOS3/HAS2/RANGRF/ATP2B4/MS4A1/LCP2/SMO	21
CC	GO:0000123	histone acetyltransferase complex	17/2684	85/19717	0.0644	0.2197	0.169	TADA3/MSL3/MSL2/SUPT20H/TAF10/BRPF1/TRRAP/TAF9B/TAF7/RUVBL2/KAT6A/KAT5/YEATS2/OGT/KAT2B/EP300/MORF4L1	17
CC	GO:0005689	U12-type spliceosomal complex	7/2684	27/19717	0.06472	0.2197	0.169	SF3B1/ZMAT5/SNRNP25/SF3B5/SNRPD2/YBX1/RBM41	7
CC	GO:0070821	tertiary granule membrane	15/2684	73/19717	0.065	0.2197	0.169	SLC2A3/NBEAL2/LILRB2/OLR1/ITGAX/RAP2C/SERPINB6/PLD1/CD93/SLC11A1/LAMTOR2/GAA/UBR4/NRAS/CD59	15
CC	GO:0009898	cytoplasmic side of plasma membrane	28/2684	154/19717	0.06559	0.2207	0.1698	RGS1/TRAF5/PTPRC/RACGAP1/PTPN7/BIRC2/KIT/PLEKHA4/GNG3/GNG12/PTPN22/FGR/FERMT2/LCK/CHUK/GM2A/TRAF3/PPP3CA/ACP1/MATK/CYLD/CD2/GNA14/KRAS/PTK2B/EXOC1/ATP2B1/TH	28
CC	GO:0030175	filopodium	20/2684	104/19717	0.06755	0.2243	0.1726	ARL4C/IQGAP2/LCP1/UNC5C/OSBPL3/HLA-G/SYNE2/FGF13/BAIAP2/FAT1/FZD3/GPM6A/EPHA4/DYNC1H1/ABI1/NF2/CIB1/CXADR/CYFIP1/PODXL	20
CC	GO:0031253	cell projection membrane	57/2684	345/19717	0.06819	0.2243	0.1726	PCDHB13/FOLR1/PLEKHO1/LCP1/TMEM231/PEMT/GABARAPL1/MACF1/HLA-G/DHRS3/SLC7A11/PEX19/ATP8B1/SYNE2/PTH1R/ADAM17/TCTN3/MTMR9/ITGA5/ASAP1/INSR/SH3YL1/EHD3/ARHGEF2/MTMR6/GABRA4/SHOC2/PLEKHA1/BBS1/BBS4/FGR/GPER1/GUCA1A/CD44/ROM1/FERMT2/CYBRD1/WLS/MXRA8/PLXND1/PKD2L1/FERMT1/LAMP5/NF2/CIB1/CDKL5/HIP1R/EPS8L2/RASGRP2/LIMA1/PTPRH/PHLPP1/ATF4/SMO/TCTN2/PODXL/ATP2B1	57
CC	GO:0000781	chromosome, telomeric region	29/2684	161/19717	0.06825	0.2243	0.1726	SMC6/SETX/SMCHD1/DCLRE1C/ERCC1/HNRNPA2B1/NBN/ATR/CHEK2/TNKS2/CHEK1/EZH2/ATM/THOC2/DNA2/ORC3/NHP2/RPA1/THOC1/SMC5/BRCA2/PML/ATRX/HMBOX1/RAD50/NABP2/WRN/CDK1/SIRT7	29
CC	GO:0016460	myosin II complex	6/2684	22/19717	0.06836	0.2243	0.1726	MYL6B/LIMCH1/MYL3/MYH4/TRIM32/MYH10	6
CC	GO:0000812	Swr1 complex	4/2684	12/19717	0.06876	0.2243	0.1726	ZNHIT1/TRRAP/RUVBL2/KAT5	4
CC	GO:0005751	mitochondrial respiratory chain complex IV	4/2684	12/19717	0.06876	0.2243	0.1726	NDUFA4L2/NDUFA4/COX6A1/COA3	4
CC	GO:0030008	TRAPP complex	4/2684	12/19717	0.06876	0.2243	0.1726	TRAPPC2L/TRAPPC10/TRAPPC8/TRAPPC11	4
CC	GO:0005666	RNA polymerase III complex	5/2684	17/19717	0.07043	0.2278	0.1752	POLR2L/POLR3C/POLR2E/POLR2F/POLR1C	5
CC	GO:0031143	pseudopodium	5/2684	17/19717	0.07043	0.2278	0.1752	MAPK3/ARRB1/VAMP7/RAF1/ACTN1	5
CC	GO:0031901	early endosome membrane	27/2684	149/19717	0.07192	0.2316	0.1782	SPHK1/HLA-C/HLA-F/SH3GL1/HLA-G/HLA-A/MTMR4/ZFYVE16/EGFR/TMEM9B/PIKFYVE/NTRK2/HLA-B/HLA-E/PDLIM4/VTI1B/CMTM6/NTRK1/SNX2/MCOLN3/WLS/PML/EPHA4/WDR91/LAMP5/SLC1A1/DNAJC13	27
CC	GO:0031968	organelle outer membrane	35/2684	201/19717	0.07338	0.2353	0.181	LTC4S/RMDN3/FIS1/VPS13C/BPHL/SNCA/SIGMAR1/SNN/CLMN/ARMCX2/BCL2A1/SYNE2/BAD/AGPAT5/PINK1/ACSL5/GK/ASS1/ANKZF1/TSPO/ARMCX1/MYOC/EPHA4/UBB/DHCR7/MCL1/ARMCX6/BCL2L2/CYB5R3/RAF1/VDAC3/ATF2/SAMM50/LPIN1/STARD7	35
CC	GO:0031674	I band	26/2684	143/19717	0.07381	0.2356	0.1813	SRI/SYNE2/PDLIM1/MYOM2/BIN1/PDLIM4/PDLIM2/MYL3/ANK3/NEBL/CRYAB/FERMT2/HSPB1/PPP1R12A/S100A1/FHOD3/SORBS2/PPP3CA/KCNN2/PARVB/ATP2B4/CACNA1D/KAT2B/FHL2/ACTN1/FLNA	26
CC	GO:0070461	SAGA-type complex	7/2684	28/19717	0.07657	0.2434	0.1873	TADA3/SUPT20H/TAF10/TRRAP/TAF9B/TAF7/KAT2B	7
CC	GO:0097542	ciliary tip	10/2684	45/19717	0.0772	0.2443	0.188	IFT46/IFT52/DYNLRB1/CLUAP1/IFT140/CYLD/CDKL5/IFT22/SMO/DYNC2LI1	10
CC	GO:0032155	cell division site part	13/2684	63/19717	0.07967	0.2511	0.1932	ECT2/NDE1/RACGAP1/DCTN3/RALA/CEP55/TUBGCP5/NF2/CENPC/LIMA1/KIF20A/TUBGCP2/MYH10	13
CC	GO:0005790	smooth endoplasmic reticulum	8/2684	34/19717	0.08188	0.257	0.1977	SRI/PGRMC1/KCNJ2/DNAJC3/PPIB/HSPA5/GABARAP/TH	8
CC	GO:0032587	ruffle membrane	18/2684	94/19717	0.0824	0.2576	0.1982	PLEKHO1/LCP1/MACF1/ADAM17/MTMR9/ITGA5/SH3YL1/ARHGEF2/MTMR6/PLEKHA1/FGR/FERMT1/NF2/CIB1/CDKL5/HIP1R/EPS8L2/RASGRP2	18
CC	GO:0032433	filopodium tip	5/2684	18/19717	0.08702	0.2691	0.2071	OSBPL3/FZD3/ABI1/CIB1/CYFIP1	5
CC	GO:0099092	postsynaptic density, intracellular component	5/2684	18/19717	0.08702	0.2691	0.2071	SH3GL1/TNIK/BAIAP2/ARHGEF2/CDKL5	5
CC	GO:0005657	replication fork	14/2684	70/19717	0.08742	0.2691	0.2071	NBN/POLD2/DNMT1/RPA1/RPA3/POLD4/DONSON/TOP1/RAD51C/WRN/SMARCA5/TIMELESS/RFC2/RAD51B	14
CC	GO:0030315	T-tubule	11/2684	52/19717	0.08813	0.2691	0.2071	DYSF/SCN1B/FXYD1/SRI/RTN2/BIN1/KCNJ2/ANK3/CACNB2/ATP2B4/CACNA1D	11
CC	GO:0005688	U6 snRNP	4/2684	13/19717	0.08899	0.2691	0.2071	LSM4/LSM3/LSM5/LSM2	4
CC	GO:0016580	Sin3 complex	4/2684	13/19717	0.08899	0.2691	0.2071	ING2/NCOR1/HDAC1/MORF4L1	4
CC	GO:0030130	clathrin coat of trans-Golgi network vesicle	4/2684	13/19717	0.08899	0.2691	0.2071	AP1G2/AP1S1/AFTPH/SYNRG	4
CC	GO:0042627	chylomicron	4/2684	13/19717	0.08899	0.2691	0.2071	APOE/APOC1/LPL/LSR	4
CC	GO:0005720	nuclear heterochromatin	8/2684	35/19717	0.09407	0.2833	0.218	SUZ12/FOXC1/ATRX/SATB1/EED/CENPC/RING1/SIRT7	8
CC	GO:0031233	intrinsic component of external side of plasma membrane	6/2684	24/19717	0.09764	0.2921	0.2247	FOLR1/PRNP/EFNA5/FOLR2/PRND/CD59	6
CC	GO:0070160	tight junction	23/2684	128/19717	0.09776	0.2921	0.2247	ECT2/MICALL2/RAP2C/CDK4/MAGI2/ARHGEF2/PMP22/ANK3/CLDN11/CDH5/LIN7B/MXRA8/PRKCI/RAB13/SIPA1L3/MTDH/AMOTL2/LSR/TJP2/CXADR/UBN1/VAPA/PLXDC1	23
CC	GO:0016363	nuclear matrix	20/2684	109/19717	0.09905	0.2948	0.2268	SRPK1/JAK2/HNRNPA2B1/ATXN7/THOC1/CSNK2B/LMNB1/KIF4A/PML/SATB1/SFPQ/RUVBL2/AKAP8/SMC1A/CXXC1/CEBPB/ARFGEF1/CENPF/SATB2/SORBS1	20
CC	GO:0000792	heterochromatin	15/2684	78/19717	0.103	0.3053	0.2349	SUZ12/DNMT1/FOXC1/RRP1B/PML/ATRX/SATB1/EED/HDAC1/CENPC/RING1/BAZ2A/HMGA1/HMGA2/SIRT7	15
CC	GO:0000803	sex chromosome	7/2684	30/19717	0.1038	0.3065	0.2358	SMC6/SMCHD1/SUZ12/BIRC2/SMC5/EED/RING1	7
CC	GO:0031045	dense core granule	5/2684	19/19717	0.1055	0.3101	0.2386	PENK/CRHBP/SCG2/SOD1/SYT1	5
CC	GO:0010494	cytoplasmic stress granule	13/2684	66/19717	0.1066	0.3121	0.2402	CIRBP/PUM2/HNRNPK/ROCK1/PABPC3/TIA1/LARP4/KPNB1/DDX1/YBX1/TARDBP/CTSG/STAU1	13
CC	GO:0008180	COP9 signalosome	8/2684	36/19717	0.1072	0.3129	0.2408	TMOD1/COPS6/COPS7A/COPS8/HSPA6/LAT/STOML2/HSPA5	8
CC	GO:0030173	integral component of Golgi membrane	12/2684	60/19717	0.1079	0.3137	0.2414	ENTPD4/YIF1A/TPST1/SLC35A2/PCSK7/RFNG/ERGIC3/MAN1C1/TEX261/SGMS1/UNC50/CHST12	12
CC	GO:0005791	rough endoplasmic reticulum	16/2684	85/19717	0.1094	0.3137	0.2414	SNCA/SLC7A11/LRPAP1/BAIAP2/KCNJ2/HCRT/MYOC/PTGDS/SUCO/SEC61A2/RANGRF/NUCB1/ARSB/TMEM97/STAU1/NCF1	16
CC	GO:0043197	dendritic spine	29/2684	169/19717	0.1101	0.3137	0.2414	SRI/SYT11/DOCK10/COMT/BAIAP2/ASAP1/NTRK2/PDLIM4/PSMC2/KCNJ2/GRIA2/GPER1/SIPA1L1/GPM6A/CRYAB/ARRB1/CD3E/EPHA4/USP8/P2RX4/PPP3CA/NRGN/KCNN2/CTTN/HIP1R/CYFIP1/PTK2B/MYH10/ATP2B1	29
CC	GO:0000346	transcription export complex	4/2684	14/19717	0.1117	0.3137	0.2414	THOC2/DDX39A/THOC1/NXF1	4
CC	GO:0000940	condensed chromosome outer kinetochore	4/2684	14/19717	0.1117	0.3137	0.2414	BUB1B/NDC80/CCNB1/CENPF	4
CC	GO:0005750	mitochondrial respiratory chain complex III	4/2684	14/19717	0.1117	0.3137	0.2414	UQCR10/CYC1/UQCRQ/UQCRC1	4
CC	GO:0033162	melanosome membrane	4/2684	14/19717	0.1117	0.3137	0.2414	MREG/RAB27A/DCT/TH	4
CC	GO:0045009	chitosome	4/2684	14/19717	0.1117	0.3137	0.2414	MREG/RAB27A/DCT/TH	4
CC	GO:0045275	respiratory chain complex III	4/2684	14/19717	0.1117	0.3137	0.2414	UQCR10/CYC1/UQCRQ/UQCRC1	4
CC	GO:0090741	pigment granule membrane	4/2684	14/19717	0.1117	0.3137	0.2414	MREG/RAB27A/DCT/TH	4
CC	GO:0005802	trans-Golgi network	39/2684	236/19717	0.1135	0.3175	0.2443	HLA-DRB4/YIPF2/NBEA/PREPL/LAP3/ARFIP1/CBY1/ATP2C1/AP1B1/RABEPK/ARL1/PCSK7/STX10/GSAP/TMEM230/GPER1/SYT17/POSTN/VAMP3/WLS/RAB13/VAMP7/ATP8A1/AP4S1/AP1S1/HLA-DQB1/LGR5/AFTPH/OPTN/VAMP2/ATP11B/WDR11/GOLGA1/GOLGA4/GOLPH3/NUCB1/ARFGEF1/YIPF1/AP4M1	39
CC	GO:0032154	cleavage furrow	11/2684	55/19717	0.1203	0.334	0.257	ECT2/NDE1/RACGAP1/DCTN3/RALA/CEP55/NF2/CENPC/LIMA1/KIF20A/MYH10	11
CC	GO:1904724	tertiary granule lumen	11/2684	55/19717	0.1203	0.334	0.257	PGM1/TIMP2/ASAH1/GGH/QPCT/HBB/CRISP3/GSDMD/ALDOC/CYFIP1/CFP	11
CC	GO:1902562	H4 histone acetyltransferase complex	9/2684	43/19717	0.122	0.3374	0.2596	TADA3/MSL3/MSL2/TRRAP/RUVBL2/KAT5/YEATS2/KAT2B/MORF4L1	9
CC	GO:0044309	neuron spine	29/2684	171/19717	0.1226	0.3374	0.2596	SRI/SYT11/DOCK10/COMT/BAIAP2/ASAP1/NTRK2/PDLIM4/PSMC2/KCNJ2/GRIA2/GPER1/SIPA1L1/GPM6A/CRYAB/ARRB1/CD3E/EPHA4/USP8/P2RX4/PPP3CA/NRGN/KCNN2/CTTN/HIP1R/CYFIP1/PTK2B/MYH10/ATP2B1	29
CC	GO:0005741	mitochondrial outer membrane	30/2684	178/19717	0.1251	0.3374	0.2596	RMDN3/FIS1/VPS13C/BPHL/SNCA/SNN/ARMCX2/BCL2A1/BAD/AGPAT5/PINK1/ACSL5/GK/ASS1/ANKZF1/TSPO/ARMCX1/MYOC/EPHA4/UBB/MCL1/ARMCX6/BCL2L2/CYB5R3/RAF1/VDAC3/ATF2/SAMM50/LPIN1/STARD7	30
CC	GO:0005868	cytoplasmic dynein complex	5/2684	20/19717	0.1256	0.3374	0.2596	TPR/DYNLRB1/DYNC1I1/DYNC1H1/DYNC2LI1	5
CC	GO:0035267	NuA4 histone acetyltransferase complex	5/2684	20/19717	0.1256	0.3374	0.2596	MSL3/TRRAP/RUVBL2/KAT5/MORF4L1	5
CC	GO:0035371	microtubule plus-end	5/2684	20/19717	0.1256	0.3374	0.2596	MAPRE3/SPAG5/KIF18B/CLASP1/MAPRE2	5
CC	GO:0043189	H4/H2A histone acetyltransferase complex	5/2684	20/19717	0.1256	0.3374	0.2596	MSL3/TRRAP/RUVBL2/KAT5/MORF4L1	5
CC	GO:0045277	respiratory chain complex IV	5/2684	20/19717	0.1256	0.3374	0.2596	NDUFA4L2/NDUFA4/COX8A/COX6A1/COA3	5
CC	GO:0030018	Z disc	23/2684	132/19717	0.1258	0.3374	0.2596	SRI/SYNE2/PDLIM1/MYOM2/BIN1/PDLIM4/PDLIM2/ANK3/NEBL/CRYAB/HSPB1/PPP1R12A/S100A1/FHOD3/SORBS2/PPP3CA/KCNN2/PARVB/ATP2B4/CACNA1D/FHL2/ACTN1/FLNA	23
CC	GO:0043679	axon terminus	21/2684	119/19717	0.126	0.3374	0.2596	MICAL1/SLC18A2/SNCA/SRI/ATP6V0D1/GOT1/PRKCB/SYT11/SYNJ1/NTRK2/PENK/GPER1/POLG/PTPRN2/CRHBP/EPHA4/AP1S1/P2RX4/PNOC/CYFIP1/TH	21
CC	GO:0097733	photoreceptor cell cilium	20/2684	113/19717	0.13	0.3469	0.2669	PTGS1/PCDHB13/CETN2/ARL3/RAB27A/RPGR/DHRS3/MERTK/IFT52/SHOC2/BBS4/GUCA1A/ROM1/IFT140/IQCB1/PRPH2/PTPRK/PDC/CEP290/PHLPP1	20
CC	GO:0005640	nuclear outer membrane	6/2684	26/19717	0.1325	0.3523	0.271	LTC4S/SNCA/SIGMAR1/CLMN/SYNE2/DHCR7	6
CC	GO:0036064	ciliary basal body	23/2684	133/19717	0.1335	0.3537	0.2721	CETN2/IFT46/MLF1/RPGR/CBY1/IFT52/C2CD3/BBS1/BBS4/RABEP2/B9D1/CDC14A/PCM1/CSNK1A1/IFT140/ARHGAP35/WDR11/CYLD/CDKL5/CEP290/OFD1/CENPF/DYNC2LI1	23
CC	GO:0014704	intercalated disc	10/2684	50/19717	0.1344	0.3547	0.2729	SCN1B/ATP1B1/CDH2/FXYD1/FGF13/KCNJ2/ANK3/YWHAH/RANGRF/ACTN1	10
CC	GO:0000124	SAGA complex	4/2684	15/19717	0.1367	0.3583	0.2757	TADA3/SUPT20H/TRRAP/TAF9B	4
CC	GO:0031616	spindle pole centrosome	4/2684	15/19717	0.1367	0.3583	0.2757	NDE1/DLGAP5/NUBP2/AURKB	4
CC	GO:0001750	photoreceptor outer segment	16/2684	88/19717	0.1373	0.3585	0.2758	PTGS1/PCDHB13/RAB27A/RPGR/DHRS3/MERTK/SHOC2/BBS4/GUCA1A/ROM1/IFT140/IQCB1/PRPH2/PTPRK/PDC/PHLPP1	16
CC	GO:0005881	cytoplasmic microtubule	13/2684	69/19717	0.1382	0.3585	0.2758	TUBG2/ARL3/MAPRE3/KIF18B/CLASP1/DYNC1H1/MTUS2/CYLD/GTSE1/BCL10/MAPRE2/TUBGCP2/DYNC2LI1	13
CC	GO:0005905	clathrin-coated pit	13/2684	69/19717	0.1382	0.3585	0.2758	SPHK1/FNBP1/TFRC/SYNJ1/FCHSD2/AP2M1/SELE/LRP3/ARRB1/AP1S1/SORT1/CTTN/HIP1R	13
CC	GO:0000502	proteasome complex	12/2684	63/19717	0.1417	0.3662	0.2817	PSMB9/IDE/PSMC2/HSPB1/PSMB6/PSMC3/PSMD8/UBQLN4/PSMB5/PSMD10/PAAF1/USP14	12
CC	GO:0000815	ESCRT III complex	3/2684	10/19717	0.1451	0.3684	0.2834	CHMP6/CHMP2A/CHMP1B	3
CC	GO:0031313	extrinsic component of endosome membrane	3/2684	10/19717	0.1451	0.3684	0.2834	USP8/WDR91/SNX10	3
CC	GO:0033179	proton-transporting V-type ATPase, V0 domain	3/2684	10/19717	0.1451	0.3684	0.2834	ATP6V0D1/TCIRG1/ATP6V0E2	3
CC	GO:0072546	ER membrane protein complex	3/2684	10/19717	0.1451	0.3684	0.2834	EMC2/EMC9/EMC7	3
CC	GO:0097197	tetraspanin-enriched microdomain	3/2684	10/19717	0.1451	0.3684	0.2834	TSPAN15/SAMHD1/CD81	3
CC	GO:0000242	pericentriolar material	5/2684	21/19717	0.1474	0.3684	0.2834	TUBG2/TNKS2/BBS4/LCK/PCM1	5
CC	GO:0000930	gamma-tubulin complex	5/2684	21/19717	0.1474	0.3684	0.2834	TUBG2/TUBGCP5/MZT2B/CEP290/TUBGCP2	5
CC	GO:0042827	platelet dense granule	5/2684	21/19717	0.1474	0.3684	0.2834	CTSW/ABCC4/ITIH4/CD63/SERPINA4	5
CC	GO:0099091	postsynaptic specialization, intracellular component	5/2684	21/19717	0.1474	0.3684	0.2834	SH3GL1/TNIK/BAIAP2/ARHGEF2/CDKL5	5
CC	GO:0097731	9+0 non-motile cilium	20/2684	115/19717	0.1474	0.3684	0.2834	PTGS1/PCDHB13/CETN2/ARL3/RAB27A/RPGR/DHRS3/MERTK/IFT52/SHOC2/BBS4/GUCA1A/ROM1/IFT140/IQCB1/PRPH2/PTPRK/PDC/CEP290/PHLPP1	20
CC	GO:0030119	AP-type membrane coat adaptor complex	9/2684	45/19717	0.1505	0.3747	0.2883	AP1B1/AP1G2/AP2M1/AP4S1/AP1S1/AFTPH/SYNRG/HIP1R/AP4M1	9
CC	GO:0030990	intraciliary transport particle	6/2684	27/19717	0.1519	0.3768	0.2899	IFT46/IFT52/CLUAP1/IFT140/IFT22/DYNC2LI1	6
CC	GO:0032391	photoreceptor connecting cilium	8/2684	39/19717	0.1524	0.3768	0.2899	PCDHB13/CETN2/ARL3/IFT52/BBS4/IFT140/IQCB1/CEP290	8
CC	GO:1905369	endopeptidase complex	12/2684	64/19717	0.154	0.3797	0.2922	PSMB9/IDE/PSMC2/HSPB1/PSMB6/PSMC3/PSMD8/UBQLN4/PSMB5/PSMD10/PAAF1/USP14	12
CC	GO:0030863	cortical cytoskeleton	20/2684	116/19717	0.1566	0.3849	0.2961	CDH2/GYPC/RIMS3/TMOD1/ACTR3/CAPZA1/HFE/EPB42/SELE/WIPF1/CLASP1/LLGL2/CALB2/NF2/CTTN/AKAP13/MPP1/HIP1R/FLNA/ACTR2	20
CC	GO:0005923	bicellular tight junction	21/2684	123/19717	0.1604	0.3929	0.3023	ECT2/MICALL2/RAP2C/CDK4/MAGI2/ARHGEF2/PMP22/ANK3/CLDN11/CDH5/LIN7B/MXRA8/PRKCI/RAB13/MTDH/AMOTL2/TJP2/CXADR/UBN1/VAPA/PLXDC1	21
CC	GO:0044291	cell-cell contact zone	13/2684	71/19717	0.1619	0.3952	0.3041	PCDH9/SCN1B/ATP1B1/CDH2/FXYD1/FGF13/RAP2C/PECAM1/KCNJ2/ANK3/YWHAH/RANGRF/ACTN1	13
CC	GO:0017053	transcriptional repressor complex	15/2684	84/19717	0.1633	0.3957	0.3045	N4BP2L2/ELANE/RELB/GATAD2A/INSM1/RBPJ/HMGB1/CHD3/ARID4A/NCOR1/RCOR1/SMARCA5/HDAC1/SPEN/BAZ2A	15
CC	GO:0042575	DNA polymerase complex	4/2684	16/19717	0.1637	0.3957	0.3045	POLD2/DNA2/POLD4/POLG	4
CC	GO:0070822	Sin3-type complex	4/2684	16/19717	0.1637	0.3957	0.3045	ING2/NCOR1/HDAC1/MORF4L1	4
CC	GO:0030118	clathrin coat	9/2684	46/19717	0.1659	0.3998	0.3076	SYNJ1/AP1B1/AP1G2/AP2M1/AP1S1/AFTPH/SYNRG/HIP1R/AP4M1	9
CC	GO:0031228	intrinsic component of Golgi membrane	12/2684	65/19717	0.1669	0.4009	0.3085	ENTPD4/YIF1A/TPST1/SLC35A2/PCSK7/RFNG/ERGIC3/MAN1C1/TEX261/SGMS1/UNC50/CHST12	12
CC	GO:0035579	specific granule membrane	16/2684	91/19717	0.1689	0.4037	0.3106	SLC2A3/TNFRSF1B/STK10/OLR1/ITGAL/TMEM30A/PGRMC1/PLD1/CD93/CMTM6/ATP8A1/SLC2A5/LAMTOR2/UBR4/ALDH3B1/CD59	16
CC	GO:0032590	dendrite membrane	8/2684	40/19717	0.1691	0.4037	0.3106	GABARAPL1/INSR/GABRA4/GPER1/WLS/LAMP5/ATF4/ATP2B1	8
CC	GO:0000314	organellar small ribosomal subunit	6/2684	28/19717	0.1724	0.4076	0.3136	MRPS33/MRPS28/MRPS17/MRPS22/MRPS11/MRPS14	6
CC	GO:0005763	mitochondrial small ribosomal subunit	6/2684	28/19717	0.1724	0.4076	0.3136	MRPS33/MRPS28/MRPS17/MRPS22/MRPS11/MRPS14	6
CC	GO:0044295	axonal growth cone	6/2684	28/19717	0.1724	0.4076	0.3136	TRAK1/GPM6A/KIF5C/EPHA4/TRPV2/CYFIP1	6
CC	GO:0098562	cytoplasmic side of membrane	29/2684	178/19717	0.1733	0.4083	0.3141	RGS1/TRAF5/PTPRC/RACGAP1/PTPN7/BIRC2/KIT/PLEKHA4/GNG3/DNAJA1/GNG12/PTPN22/FGR/FERMT2/LCK/CHUK/GM2A/TRAF3/PPP3CA/ACP1/MATK/CYLD/CD2/GNA14/KRAS/PTK2B/EXOC1/ATP2B1/TH	29
CC	GO:0000784	nuclear chromosome, telomeric region	21/2684	125/19717	0.1793	0.4144	0.3188	SMCHD1/DCLRE1C/ERCC1/NBN/ATR/TNKS2/ATM/THOC2/DNA2/ORC3/NHP2/RPA1/THOC1/BRCA2/PML/ATRX/HMBOX1/RAD50/NABP2/CDK1/SIRT7	21
CC	GO:0044445	cytosolic part	39/2684	247/19717	0.1801	0.4144	0.3188	AIM2/PRKCB/CFLAR/NLRP1/BAIAP2/CARD8/CASP4/RRM2/BLOC1S1/IDE/MMS19/ENO2/RPS8/RPL12/PFKM/RPS11/APAF1/CHUK/LARP4/RPL10A/UBL4A/CASP9/KXD1/RPS5/PIN1/UBQLN4/HBB/EIF2D/RPL27A/CYB5R3/GSDMD/RPL8/IKBKG/HPS5/CCT6B/RPL19/CCT8L2/RPL35A/RPLP0	39
CC	GO:0019774	proteasome core complex, beta-subunit complex	3/2684	11/19717	0.1803	0.4144	0.3188	PSMB9/PSMB6/PSMB5	3
CC	GO:0031932	TORC2 complex	3/2684	11/19717	0.1803	0.4144	0.3188	PRR5L/MLST8/SESN1	3
CC	GO:0034663	endoplasmic reticulum chaperone complex	3/2684	11/19717	0.1803	0.4144	0.3188	MZB1/PPIB/HSPA5	3
CC	GO:0042589	zymogen granule membrane	3/2684	11/19717	0.1803	0.4144	0.3188	TMED2/VAMP2/TMED10	3
CC	GO:0072687	meiotic spindle	3/2684	11/19717	0.1803	0.4144	0.3188	ASPM/HSPA2/FBXO5	3
CC	GO:1990907	beta-catenin-TCF complex	3/2684	11/19717	0.1803	0.4144	0.3188	LEF1/TLE3/TCF7L2	3
CC	GO:0043292	contractile fiber	37/2684	234/19717	0.1851	0.4241	0.3263	MYL6B/SRI/TMOD1/PDE4DIP/SYNE2/IDO1/PDLIM1/SCO2/MYOM2/PECAM1/BIN1/PDLIM4/PDLIM2/MYL3/ANK3/NEBL/CRYAB/FERMT2/HSPB1/PPP1R12A/S100A1/TMOD2/FHOD3/SORBS2/TIMP4/MYL4/PPP3CA/KCNN2/MYH4/PARVB/ATP2B4/CACNA1D/KAT2B/FHL2/TRIM32/ACTN1/FLNA	37
CC	GO:0098793	presynapse	74/2684	491/19717	0.1864	0.4252	0.3272	PTN/SPHK1/MICAL1/CDH2/SLC18A2/GAK/SNCA/SRI/ATP6V0D1/RIMS3/SH3GL1/GOT1/PRKCB/SYT11/TNIK/SLC29A1/FXYD6/SYNJ1/DMXL2/PFN2/BAIAP2/MCTP1/ZDHHC17/ADAM23/NTRK2/PCDH17/NTF3/BIN1/SEC22B/STX10/SEMA4C/PENK/TMEM230/VTI1B/HRH3/FZD3/GPER1/GPM6A/SYT17/VAMP3/LIN7B/POLG/ATP2B2/PTPRN2/CRHBP/SNCAIP/HCRT/VAMP7/EPHA4/AP1S1/P2RX4/PNOC/CADM3/SV2B/VAMP2/CACNB2/EXOC3/TMED9/CALB2/LAMP5/ATP2B4/CACNA1D/GABBR1/RAB11B/SYT1/ERBB4/CYFIP1/RAB15/SYN1/NAPA/APH1A/BDNF/ATP2B1/TH	74
CC	GO:0099056	integral component of presynaptic membrane	13/2684	73/19717	0.1875	0.4252	0.3272	CDH2/SYT11/FXYD6/ADAM23/PCDH17/GPM6A/EPHA4/CADM3/ATP2B4/CACNA1D/ERBB4/APH1A/ATP2B1	13
CC	GO:0070382	exocytic vesicle	33/2684	207/19717	0.1877	0.4252	0.3272	SLC18A2/SNCA/ATP6V0D1/SYT11/RAB27A/DMXL2/MCTP1/NTF3/BIN1/SEC22B/STX10/SEMA4C/PENK/TMEM230/VTI1B/SYT17/VAMP3/PTPRN2/IGF1/SNCAIP/HCRT/VAMP7/SV2B/VAMP2/TMED9/LAMP5/RAB11B/SYT1/RAB15/SYN1/APH1A/BDNF/TH	33
CC	GO:0014069	postsynaptic density	50/2684	324/19717	0.1878	0.4252	0.3272	CDH2/SIGMAR1/SH3GL1/SYT11/TNIK/SPOCK1/SOS1/NETO2/ARHGEF9/PRNP/BAIAP2/NCK2/NTRK2/SEMA4C/MAGI2/ARHGEF2/GNG3/RPL12/GRIA2/GPER1/SIPA1L1/ADAM22/CRYAB/ARRB1/LIN7B/DGKZ/CHRNA3/ATP2B2/RPL10A/ADCY1/EPHA4/EIF3A/USP8/P2RX4/HOMER3/CAMK1/NRGN/ABI1/AKAP9/RPL8/KPNA1/CDKL5/HIP1R/PAK2/ERBB4/SYN1/PTK2B/ACTR2/BCL11A/RPLP0	50
CC	GO:0044449	contractile fiber part	35/2684	221/19717	0.1902	0.4292	0.3302	MYL6B/SRI/TMOD1/SYNE2/IDO1/PDLIM1/MYOM2/PECAM1/BIN1/PDLIM4/PDLIM2/MYL3/ANK3/NEBL/CRYAB/FERMT2/HSPB1/PPP1R12A/S100A1/TMOD2/FHOD3/SORBS2/TIMP4/MYL4/PPP3CA/KCNN2/MYH4/PARVB/ATP2B4/CACNA1D/KAT2B/FHL2/TRIM32/ACTN1/FLNA	35
CC	GO:0031092	platelet alpha granule membrane	4/2684	17/19717	0.1924	0.4314	0.3319	CYB5R1/SNCA/APLP2/PECAM1	4
CC	GO:0042622	photoreceptor outer segment membrane	4/2684	17/19717	0.1924	0.4314	0.3319	DHRS3/SHOC2/ROM1/PHLPP1	4
CC	GO:0005901	caveola	14/2684	80/19717	0.1937	0.4314	0.3319	ATP1B1/JAK2/FXYD1/MAPK3/INSR/EFNA5/PLVAP/SELE/TFPI/F2R/NOS3/RANGRF/ATP2B4/SMO	14
CC	GO:0030125	clathrin vesicle coat	6/2684	29/19717	0.194	0.4314	0.3319	AP1G2/AP2M1/AP1S1/AFTPH/SYNRG/HIP1R	6
CC	GO:1990752	microtubule end	6/2684	29/19717	0.194	0.4314	0.3319	ASPM/MAPRE3/SPAG5/KIF18B/CLASP1/MAPRE2	6
CC	GO:0099572	postsynaptic specialization	53/2684	348/19717	0.2074	0.4598	0.3538	CDH2/SIGMAR1/SH3GL1/SYT11/TNIK/SPOCK1/SOS1/NETO2/ARHGEF9/KPNA2/PRNP/BAIAP2/NCK2/NTRK2/SEMA4C/MAGI2/ARHGEF2/GNG3/GABRA4/RPL12/GRIA2/GPER1/SIPA1L1/ADAM22/CRYAB/ARRB1/LIN7B/DGKZ/CHRNA3/ATP2B2/RPL10A/ADCY1/EPHA4/EIF3A/USP8/P2RX4/HOMER3/CHRNB1/CAMK1/NRGN/ABI1/AKAP9/RPL8/KPNA1/CDKL5/HIP1R/PAK2/ERBB4/SYN1/PTK2B/ACTR2/BCL11A/RPLP0	53
CC	GO:0032279	asymmetric synapse	50/2684	328/19717	0.2133	0.4709	0.3623	CDH2/SIGMAR1/SH3GL1/SYT11/TNIK/SPOCK1/SOS1/NETO2/ARHGEF9/PRNP/BAIAP2/NCK2/NTRK2/SEMA4C/MAGI2/ARHGEF2/GNG3/RPL12/GRIA2/GPER1/SIPA1L1/ADAM22/CRYAB/ARRB1/LIN7B/DGKZ/CHRNA3/ATP2B2/RPL10A/ADCY1/EPHA4/EIF3A/USP8/P2RX4/HOMER3/CAMK1/NRGN/ABI1/AKAP9/RPL8/KPNA1/CDKL5/HIP1R/PAK2/ERBB4/SYN1/PTK2B/ACTR2/BCL11A/RPLP0	50
CC	GO:0048787	presynaptic active zone membrane	6/2684	30/19717	0.2166	0.4709	0.3623	CDH2/SYT11/GPM6A/ATP2B4/CACNA1D/ATP2B1	6
CC	GO:0008540	proteasome regulatory particle, base subcomplex	3/2684	12/19717	0.2175	0.4709	0.3623	PSMC2/PSMC3/PSMD10	3
CC	GO:0030877	beta-catenin destruction complex	3/2684	12/19717	0.2175	0.4709	0.3623	CTNNBIP1/GSK3B/CSNK1A1	3
CC	GO:0030914	STAGA complex	3/2684	12/19717	0.2175	0.4709	0.3623	TADA3/TAF10/TRRAP	3
CC	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	3/2684	12/19717	0.2175	0.4709	0.3623	DET1/GLMN/DTL	3
CC	GO:0048188	Set1C/COMPASS complex	3/2684	12/19717	0.2175	0.4709	0.3623	WDR5B/SETD1B/CXXC1	3
CC	GO:0060198	clathrin-sculpted vesicle	3/2684	12/19717	0.2175	0.4709	0.3623	SLC18A2/VAMP2/SYT1	3
CC	GO:0030017	sarcomere	32/2684	204/19717	0.2189	0.4727	0.3637	SRI/TMOD1/SYNE2/PDLIM1/MYOM2/BIN1/PDLIM4/PDLIM2/MYL3/ANK3/NEBL/CRYAB/FERMT2/HSPB1/PPP1R12A/S100A1/TMOD2/FHOD3/SORBS2/TIMP4/MYL4/PPP3CA/KCNN2/MYH4/PARVB/ATP2B4/CACNA1D/KAT2B/FHL2/TRIM32/ACTN1/FLNA	32
CC	GO:0098984	neuron to neuron synapse	53/2684	350/19717	0.2202	0.4741	0.3648	CDH2/SIGMAR1/SH3GL1/SYT11/TNIK/SPOCK1/SOS1/NETO2/ARHGEF9/PRNP/BAIAP2/NCK2/NTRK2/SEMA4C/PENK/MAGI2/ARHGEF2/GNG3/RPL12/GRIA2/GPER1/SIPA1L1/ADAM22/CRYAB/ARRB1/LIN7B/DGKZ/CHRNA3/ATP2B2/VAMP7/RPL10A/ADCY1/EPHA4/EIF3A/USP8/P2RX4/HOMER3/CAMK1/NRGN/ABI1/AKAP9/RPL8/KPNA1/CDKL5/HIP1R/PAK2/SYT1/ERBB4/SYN1/PTK2B/ACTR2/BCL11A/RPLP0	53
CC	GO:0005859	muscle myosin complex	4/2684	18/19717	0.2225	0.4762	0.3664	MYL6B/MYL3/MYH4/TRIM32	4
CC	GO:0090723	growth cone part	4/2684	18/19717	0.2225	0.4762	0.3664	EXOC7/LAMP5/TRPV2/CYFIP1	4
CC	GO:0008021	synaptic vesicle	30/2684	191/19717	0.2256	0.481	0.3701	SLC18A2/SNCA/ATP6V0D1/SYT11/DMXL2/MCTP1/NTF3/BIN1/SEC22B/STX10/SEMA4C/PENK/TMEM230/VTI1B/VAMP3/PTPRN2/SNCAIP/HCRT/VAMP7/SV2B/VAMP2/TMED9/LAMP5/RAB11B/SYT1/RAB15/SYN1/APH1A/BDNF/TH	30
CC	GO:0019898	extrinsic component of membrane	45/2684	295/19717	0.226	0.481	0.3701	MICALL1/CDH2/SOCS6/VPS13C/RGS1/KPNA2/PRNP/RACGAP1/GFRA1/SOCS1/TPR/PLEKHA4/GNG3/PIK3C2B/COQ6/GNG12/FGR/FERMT2/ATG2B/CDH5/LCK/PIK3CB/PIK3R5/PML/USP8/WDR91/ATG13/RS1/SNX10/CDH12/MATK/AKAP9/CYLD/PIK3CD/FCN1/GNA14/NUCB1/KRAS/PIK3C2G/SYN1/PTK2B/STOML2/CISH/PIK3CA/NCF1	45
CC	GO:0030117	membrane coat	16/2684	96/19717	0.2288	0.4842	0.3725	COPZ2/SEC24A/SYNJ1/AP1B1/TMED3/AP1G2/AP2M1/SEC13/CHMP2A/AP4S1/AP1S1/AFTPH/SYNRG/CHMP1B/HIP1R/AP4M1	16
CC	GO:0048475	coated membrane	16/2684	96/19717	0.2288	0.4842	0.3725	COPZ2/SEC24A/SYNJ1/AP1B1/TMED3/AP1G2/AP2M1/SEC13/CHMP2A/AP4S1/AP1S1/AFTPH/SYNRG/CHMP1B/HIP1R/AP4M1	16
CC	GO:0016592	mediator complex	7/2684	37/19717	0.232	0.4893	0.3765	MED13/MED1/CDK8/MED13L/MED23/MED7/MED27	7
CC	GO:0045334	clathrin-coated endocytic vesicle	11/2684	63/19717	0.2325	0.4893	0.3765	HLA-DRB4/CTLA4/APOE/AP2M1/HBEGF/HLA-DQB1/LMBRD1/HIP1R/CPNE6/FZD2/SFTPC	11
CC	GO:0071005	U2-type precatalytic spliceosome	9/2684	50/19717	0.2342	0.4913	0.378	LSM4/SF3B1/LSM3/SF3B5/LSM5/SNIP1/SNRPD2/TXNL4A/LSM2	9
CC	GO:1904115	axon cytoplasm	10/2684	57/19717	0.2423	0.5069	0.39	UCHL1/BLOC1S1/TRAK1/HSPB1/KIF5C/KIF4A/DYNC1H1/SOD1/SPAST/HIF1A	10
CC	GO:0000932	P-body	14/2684	84/19717	0.2482	0.5173	0.398	LSM4/APOBEC3C/LSM3/PSMC2/RC3H2/BTBD2/DCP2/TRIM21/PSMC3/POLR2G/TOP1/AGO3/EDC4/LSM2	14
CC	GO:0060170	ciliary membrane	15/2684	91/19717	0.2519	0.5173	0.398	PCDHB13/TMEM231/DHRS3/TCTN3/EHD3/SHOC2/BBS1/BBS4/GUCA1A/ROM1/MXRA8/PKD2L1/PHLPP1/SMO/TCTN2	15
CC	GO:0005771	multivesicular body	9/2684	51/19717	0.2526	0.5173	0.398	RAB27A/EGFR/CD63/CRHBP/CHMP2A/CST7/CHMP1B/NEDD4L/SFTPC	9
CC	GO:0044420	extracellular matrix component	9/2684	51/19717	0.2526	0.5173	0.398	MFAP4/FBLN5/LAMA5/COL15A1/COL5A3/COL4A1/FBLN1/COL3A1/COL4A2	9
CC	GO:0045178	basal part of cell	9/2684	51/19717	0.2526	0.5173	0.398	EGFR/SLC27A5/HFE/ERBB2/ANK3/CLCA2/KRT14/CLASP1/ERBB4	9
CC	GO:0071011	precatalytic spliceosome	9/2684	51/19717	0.2526	0.5173	0.398	LSM4/SF3B1/LSM3/SF3B5/LSM5/SNIP1/SNRPD2/TXNL4A/LSM2	9
CC	GO:0000145	exocyst	4/2684	19/19717	0.2537	0.5173	0.398	EXOC7/EXOC2/EXOC3/EXOC1	4
CC	GO:0030992	intraciliary transport particle B	4/2684	19/19717	0.2537	0.5173	0.398	IFT46/IFT52/CLUAP1/IFT22	4
CC	GO:0098644	complex of collagen trimers	4/2684	19/19717	0.2537	0.5173	0.398	COL5A3/COL4A1/COL3A1/COL4A2	4
CC	GO:0098858	actin-based cell projection	32/2684	208/19717	0.2541	0.5173	0.398	AKR1B1/ARL4C/IQGAP2/LCP1/UNC5C/ANGPT1/OSBPL3/HLA-G/ATP8B1/SYNE2/FGF13/FCHSD2/BAIAP2/FAT1/FZD3/CDC14A/GPM6A/CD44/EPHA4/DYNC1H1/CA2/ABI1/CALB2/NF2/CIB1/MPP1/EPS8L2/CXADR/CYFIP1/PTPRH/SLC4A7/PODXL	32
CC	GO:0008250	oligosaccharyltransferase complex	3/2684	13/19717	0.256	0.5183	0.3988	TMEM258/DAD1/DDOST	3
CC	GO:0044292	dendrite terminus	3/2684	13/19717	0.256	0.5183	0.3988	IFT52/CDKL5/CYFIP1	3
CC	GO:0000118	histone deacetylase complex	10/2684	58/19717	0.2598	0.5216	0.4013	PHF21A/ZNF217/ING2/GATAD2A/CHD3/NCOR1/HDAC1/SAP30/MORF4L1/SATB2	10
CC	GO:0005637	nuclear inner membrane	10/2684	58/19717	0.2598	0.5216	0.4013	LBR/SIGMAR1/SMAD3/NPAP1/LMNB1/DPY19L2P2/TOR1AIP1/P2RX4/ATP11B/UNC50	10
CC	GO:0030120	vesicle coat	10/2684	58/19717	0.2598	0.5216	0.4013	COPZ2/SEC24A/TMED3/AP1G2/AP2M1/SEC13/AP1S1/AFTPH/SYNRG/HIP1R	10
CC	GO:0031304	intrinsic component of mitochondrial inner membrane	8/2684	45/19717	0.2637	0.5268	0.4053	MPC2/TMEM11/SCO2/APOO/COA3/SFXN1/COQ2/MPC1	8
CC	GO:0031305	integral component of mitochondrial inner membrane	8/2684	45/19717	0.2637	0.5268	0.4053	MPC2/TMEM11/SCO2/APOO/COA3/SFXN1/COQ2/MPC1	8
CC	GO:0005938	cell cortex	46/2684	308/19717	0.2706	0.5391	0.4147	CDH2/CYTIP/FNBP1/FRYL/SNCA/GYPC/RIMS3/TMOD1/RAI14/ACTR3/NEDD9/ASTN2/CAPZA1/HFE/EXOC7/RHOF/EPB42/TRAK1/SELE/ASPH/FERMT2/PLA2G4C/CLIC5/ITPR2/ARHGEF7/WIPF1/EXOC2/RND2/CLASP1/MELK/DYNC1H1/LLGL2/SCIN/EXOC3/CALB2/NF2/CTTN/AKAP13/MPP1/RHOH/HIP1R/FLNA/PTK2B/EXOC1/ACTR2/MYH10	46
CC	GO:0030016	myofibril	34/2684	224/19717	0.2728	0.5419	0.4169	SRI/TMOD1/PDE4DIP/SYNE2/PDLIM1/SCO2/MYOM2/BIN1/PDLIM4/PDLIM2/MYL3/ANK3/NEBL/CRYAB/FERMT2/HSPB1/PPP1R12A/S100A1/TMOD2/FHOD3/SORBS2/TIMP4/MYL4/PPP3CA/KCNN2/MYH4/PARVB/ATP2B4/CACNA1D/KAT2B/FHL2/TRIM32/ACTN1/FLNA	34
CC	GO:0030894	replisome	5/2684	26/19717	0.2749	0.5435	0.4181	POLD2/RPA1/RPA3/POLD4/DONSON	5
CC	GO:0005669	transcription factor TFIID complex	7/2684	39/19717	0.2757	0.5435	0.4181	ERCC1/TAF10/GTF2A2/TAF9B/TAF7/ERCC2/GTF2H3	7
CC	GO:0031672	A band	7/2684	39/19717	0.2757	0.5435	0.4181	MYOM2/MYL3/CRYAB/PPP1R12A/S100A1/MYL4/KAT2B	7
CC	GO:0046658	anchored component of plasma membrane	10/2684	59/19717	0.2777	0.5459	0.42	FOLR1/GPC5/GAS1/PRNP/EFNA5/FOLR2/PRND/ULBP2/CD2/CD59	10
CC	GO:0099023	tethering complex	11/2684	66/19717	0.2826	0.5516	0.4244	EXOC7/VPS16/TRAPPC2L/TRAPPC10/EXOC2/TRAPPC8/VPS8/EXOC3/HOOK2/EXOC1/TRAPPC11	11
CC	GO:0030663	COPI-coated vesicle membrane	4/2684	20/19717	0.2857	0.5516	0.4244	COPZ2/KDELR3/TMED3/TMED2	4
CC	GO:0036019	endolysosome	4/2684	20/19717	0.2857	0.5516	0.4244	LGMN/AP2M1/TLR8/CLEC16A	4
CC	GO:0071682	endocytic vesicle lumen	4/2684	20/19717	0.2857	0.5516	0.4244	HSPH1/APOE/GNLY/HBB	4
CC	GO:0032592	integral component of mitochondrial membrane	12/2684	73/19717	0.2865	0.5516	0.4244	FIS1/SLC25A4/MPC2/PINK1/TMEM11/SCO2/APOO/COA3/MICU1/SFXN1/COQ2/MPC1	12
CC	GO:0016528	sarcoplasm	13/2684	80/19717	0.2897	0.5516	0.4244	ATP2A3/THBS4/SRI/SPOCK1/RTN2/SYNE2/NOL3/ASPH/ANK3/ITPR2/S100A1/FABP3/CAMK2B	13
CC	GO:0097730	non-motile cilium	23/2684	149/19717	0.2905	0.5516	0.4244	PTGS1/PCDHB13/CETN2/ARL3/RAB27A/RPGR/DHRS3/MERTK/IFT52/SHOC2/BBS4/CDC14A/GUCA1A/ROM1/IFT140/PKD2L1/IQCB1/PRPH2/PTPRK/PDC/CEP290/GALR3/PHLPP1	23
CC	GO:0000313	organellar ribosome	14/2684	87/19717	0.2924	0.5516	0.4244	MRPL24/MRPL11/MRPL40/MRPL23/MRPS33/MRPS28/MRPS17/MRPS22/MRPS11/MRPL17/MRPL20/MRPL18/MRPS14/MRPL4	14
CC	GO:0005761	mitochondrial ribosome	14/2684	87/19717	0.2924	0.5516	0.4244	MRPL24/MRPL11/MRPL40/MRPL23/MRPS33/MRPS28/MRPS17/MRPS22/MRPS11/MRPL17/MRPL20/MRPL18/MRPS14/MRPL4	14
CC	GO:0071013	catalytic step 2 spliceosome	14/2684	87/19717	0.2924	0.5516	0.4244	HNRNPA2B1/SNRNP40/SF3B1/PRPF4B/LSM3/HNRNPK/DDX23/BUD31/HNRNPA1/ZCCHC8/PPIE/SNRPD2/DDX41/LSM2	14
CC	GO:0001518	voltage-gated sodium channel complex	3/2684	14/19717	0.2954	0.5516	0.4244	SCN1B/SCN9A/SCN3A	3
CC	GO:0005767	secondary lysosome	3/2684	14/19717	0.2954	0.5516	0.4244	FTL/CRHBP/NCF1	3
CC	GO:0010369	chromocenter	3/2684	14/19717	0.2954	0.5516	0.4244	CDCA8/AURKB/PIWIL2	3
CC	GO:0030677	ribonuclease P complex	3/2684	14/19717	0.2954	0.5516	0.4244	HSD17B10/POP7/RPP14	3
CC	GO:0031089	platelet dense granule lumen	3/2684	14/19717	0.2954	0.5516	0.4244	CTSW/ITIH4/SERPINA4	3
CC	GO:0036020	endolysosome membrane	3/2684	14/19717	0.2954	0.5516	0.4244	AP2M1/TLR8/CLEC16A	3
CC	GO:0038201	TOR complex	3/2684	14/19717	0.2954	0.5516	0.4244	PRR5L/MLST8/SESN1	3
CC	GO:0042588	zymogen granule	3/2684	14/19717	0.2954	0.5516	0.4244	TMED2/VAMP2/TMED10	3
CC	GO:0043218	compact myelin	3/2684	14/19717	0.2954	0.5516	0.4244	AKR1B1/PMP22/PRKCI	3
CC	GO:0045239	tricarboxylic acid cycle enzyme complex	3/2684	14/19717	0.2954	0.5516	0.4244	BCKDHB/DLD/FH	3
CC	GO:0043296	apical junction complex	22/2684	143/19717	0.3017	0.5618	0.4322	ECT2/MICALL2/RAP2C/CDK4/MAGI2/ARHGEF2/PMP22/ANK3/CLDN11/CDH5/LIN7B/MXRA8/PRKCI/RAB13/MTDH/AMOTL2/TJP2/CXADR/UBN1/VAPA/PLXDC1/SORBS1	22
CC	GO:0030137	COPI-coated vesicle	5/2684	27/19717	0.3028	0.5618	0.4322	COPZ2/KDELR3/TMED3/TMED2/TMED10	5
CC	GO:0098573	intrinsic component of mitochondrial membrane	12/2684	74/19717	0.3031	0.5618	0.4322	FIS1/SLC25A4/MPC2/PINK1/TMEM11/SCO2/APOO/COA3/MICU1/SFXN1/COQ2/MPC1	12
CC	GO:0031201	SNARE complex	8/2684	47/19717	0.3053	0.5632	0.4333	BNIP1/SEC22B/STX10/VTI1B/VAMP3/VAMP7/VAMP2/NAPA	8
CC	GO:0098563	intrinsic component of synaptic vesicle membrane	8/2684	47/19717	0.3053	0.5632	0.4333	SYT11/STX10/VAMP3/PTPRN2/VAMP7/RAB11B/SYT1/SYN1	8
CC	GO:0005604	basement membrane	15/2684	95/19717	0.3092	0.5689	0.4377	PTN/EFEMP2/LAMC3/THBS4/EFNA5/LAMA5/COL15A1/ANG/CD151/THBS2/COL4A1/TIMP1/FBLN1/COL4A2/SERPINF1	15
CC	GO:0009925	basal plasma membrane	6/2684	34/19717	0.3138	0.5746	0.4421	EGFR/SLC27A5/ERBB2/ANK3/CLCA2/ERBB4	6
CC	GO:0030285	integral component of synaptic vesicle membrane	6/2684	34/19717	0.3138	0.5746	0.4421	SYT11/STX10/VAMP3/PTPRN2/VAMP7/SYT1	6
CC	GO:0005838	proteasome regulatory particle	4/2684	21/19717	0.3183	0.5813	0.4473	PSMC2/PSMC3/PSMD8/PSMD10	4
CC	GO:0043596	nuclear replication fork	7/2684	41/19717	0.3213	0.5847	0.4499	POLD2/RPA1/RPA3/POLD4/TOP1/SMARCA5/TIMELESS	7
CC	GO:0098889	intrinsic component of presynaptic membrane	13/2684	82/19717	0.3217	0.5847	0.4499	CDH2/SYT11/FXYD6/ADAM23/PCDH17/GPM6A/EPHA4/CADM3/ATP2B4/CACNA1D/ERBB4/APH1A/ATP2B1	13
CC	GO:0005871	kinesin complex	9/2684	55/19717	0.3305	0.5973	0.4596	NDE1/KIF2A/KIF18B/KIF5C/CENPE/KIF11/KIF4A/KIF15/KIF20A	9
CC	GO:0005911	cell-cell junction	66/2684	459/19717	0.3341	0.5973	0.4596	SGCA/AKR1B1/PCDH9/SCN1B/ATP1B1/CDH2/FXYD1/ECT2/MICALL2/ITK/ADAM17/FGF13/PIKFYVE/ITGA5/BAIAP2/PDLIM1/ACTR3/RAP2C/CDK4/PECAM1/KIT/FAT1/MAGI2/ARHGEF2/PDLIM4/PDLIM2/KLHL24/PMP22/KCNJ2/ANK3/ZAP70/CLDN11/YWHAH/KRIT1/CDH5/CD3E/LIN7B/MXRA8/PRKCI/RAB13/RASIP1/SIPA1L3/MTDH/VEGFA/CADM3/PPP3CA/AMOTL2/PTPRK/LAT/CDH12/CALB2/LSR/CD2/RANGRF/TJP2/CXADR/FABP7/ACTN1/FLNA/LCP2/RAP1B/UBN1/VAPA/PLXDC1/PODXL/SORBS1	66
CC	GO:0001673	male germ cell nucleus	3/2684	15/19717	0.335	0.5973	0.4596	TOPBP1/TCFL5/HSPA2	3
CC	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex	3/2684	15/19717	0.335	0.5973	0.4596	TADA3/YEATS2/KAT2B	3
CC	GO:0016581	NuRD complex	3/2684	15/19717	0.335	0.5973	0.4596	GATAD2A/CHD3/HDAC1	3
CC	GO:0035102	PRC1 complex	3/2684	15/19717	0.335	0.5973	0.4596	PCGF1/CBX7/RING1	3
CC	GO:0071565	nBAF complex	3/2684	15/19717	0.335	0.5973	0.4596	SS18L1/SMARCD3/ARID1A	3
CC	GO:0090545	CHD-type complex	3/2684	15/19717	0.335	0.5973	0.4596	GATAD2A/CHD3/HDAC1	3
CC	GO:0031594	neuromuscular junction	12/2684	76/19717	0.3369	0.5992	0.461	PTN/SNTA1/SPOCK1/FCHSD2/ANK3/LAMA5/F2R/POSTN/EPHA4/CHRNB1/ASCC1/MYH10	12
CC	GO:0005684	U2-type spliceosomal complex	14/2684	90/19717	0.3387	0.5994	0.4612	HTATSF1/LSM4/SNRNP40/SF3B1/LSM3/SF3B5/LSM5/BUD31/PPIE/SNIP1/SNRPD2/TXNL4A/LUC7L/LSM2	14
CC	GO:0030672	synaptic vesicle membrane	16/2684	104/19717	0.3394	0.5994	0.4612	SLC18A2/SNCA/SYT11/DMXL2/MCTP1/STX10/SEMA4C/VAMP3/PTPRN2/VAMP7/SV2B/VAMP2/LAMP5/RAB11B/SYT1/SYN1	16
CC	GO:0099501	exocytic vesicle membrane	16/2684	104/19717	0.3394	0.5994	0.4612	SLC18A2/SNCA/SYT11/DMXL2/MCTP1/STX10/SEMA4C/VAMP3/PTPRN2/VAMP7/SV2B/VAMP2/LAMP5/RAB11B/SYT1/SYN1	16
CC	GO:0046540	U4/U6 x U5 tri-snRNP complex	7/2684	42/19717	0.3446	0.6043	0.4649	LSM4/LSM3/LSM5/SNRPD2/TXNL4A/PPIH/LSM2	7
CC	GO:0097526	spliceosomal tri-snRNP complex	7/2684	42/19717	0.3446	0.6043	0.4649	LSM4/LSM3/LSM5/SNRPD2/TXNL4A/PPIH/LSM2	7
CC	GO:1990391	DNA repair complex	7/2684	42/19717	0.3446	0.6043	0.4649	CETN2/DCLRE1C/PHF21A/ERCC1/ATM/PMS2P1/RCOR1	7
CC	GO:0005682	U5 snRNP	4/2684	22/19717	0.3511	0.6113	0.4704	SNRNP40/DDX23/SNRPD2/TXNL4A	4
CC	GO:0031258	lamellipodium membrane	4/2684	22/19717	0.3511	0.6113	0.4704	SYNE2/CD44/FERMT2/PLXND1	4
CC	GO:0032982	myosin filament	4/2684	22/19717	0.3511	0.6113	0.4704	MYOM2/MYH4/TRIM32/MYH10	4
CC	GO:0044665	MLL1/2 complex	5/2684	29/19717	0.3598	0.6221	0.4787	CHD8/HCFC2/MGA/TAF7/RUVBL2	5
CC	GO:0071339	MLL1 complex	5/2684	29/19717	0.3598	0.6221	0.4787	CHD8/HCFC2/MGA/TAF7/RUVBL2	5
CC	GO:0090568	nuclear transcriptional repressor complex	5/2684	29/19717	0.3598	0.6221	0.4787	GATAD2A/CHD3/SMARCA5/HDAC1/BAZ2A	5
CC	GO:0000421	autophagosome membrane	6/2684	36/19717	0.3649	0.6295	0.4844	GABARAPL1/GABARAPL2/ENTPD4/UVRAG/MCOLN3/GABARAP	6
CC	GO:0042470	melanosome	16/2684	106/19717	0.3689	0.6335	0.4874	GCHFR/MREG/TFRC/RAB27A/BSG/SEC22B/GGH/CD63/AHCY/DCT/TMED10/PPIB/TRPV2/SERPINF1/HSPA5/TH	16
CC	GO:0048770	pigment granule	16/2684	106/19717	0.3689	0.6335	0.4874	GCHFR/MREG/TFRC/RAB27A/BSG/SEC22B/GGH/CD63/AHCY/DCT/TMED10/PPIB/TRPV2/SERPINF1/HSPA5/TH	16
CC	GO:0019005	SCF ubiquitin ligase complex	10/2684	64/19717	0.3715	0.6352	0.4887	FBXW7/SKP1/CKS1B/FBXO17/FBXL2/USP47/CKS2/TRIM21/CUL2/FBXO38	10
CC	GO:0016529	sarcoplasmic reticulum	11/2684	71/19717	0.3716	0.6352	0.4887	ATP2A3/THBS4/SRI/RTN2/SYNE2/NOL3/ASPH/ANK3/ITPR2/S100A1/CAMK2B	11
CC	GO:0042613	MHC class II protein complex	3/2684	16/19717	0.3746	0.6388	0.4915	HLA-DRB4/HLA-DOB/HLA-DQB1	3
MF	GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	19/2603	42/17697	2.105e-06	0.001896	0.001685	BIRC3/SNCA/BAD/NLRP1/CARD8/BIRC2/BIRC7/TNFAIP8/NOL3/LEF1/ARRB1/CD27/APAF1/CASP8AP2/BIRC5/NAIP/NOD1/TNFSF14/RPS6KA1	19
MF	GO:0033218	amide binding	84/2603	356/17697	4.916e-06	0.001896	0.001685	NFKBIA/TAP1/FOLR1/HLA-C/TRHDE/TREM2/SLC7A5/ECI2/CLU/HLA-F/HLA-G/HLA-A/LILRB2/KDELR3/LRPAP1/PEX19/PTH1R/NUP153/KPNA2/PRNP/NPAP1/APOE/INSR/AP2M1/HLA-B/HLA-E/PPIC/IDE/HMGCL/RXRA/GSTM4/GSAP/PGRMC1/CMA1/TMEM158/PPARG/PC/GPR1/PEX7/TAPBP/GRIA2/CRYAB/MAML1/NKTR/ADRB2/FOLR2/NPR2/CRHBP/DLD/ANG/GHSR/SCP2/VIPR1/HCRTR2/TNPO1/ITM2C/EPHA4/HLA-DQB1/GSTM3/LNPEP/CALCR/NOD2/DHCR24/SEC61A2/KPNB1/PPP3CA/PPIE/SSTR5/SRP54/PPIB/NGFR/TYMS/KPNA1/PANK3/CCKAR/GHR/GALR3/ALDH6A1/KPNA3/ANPEP/PSAP/NUP98/ACBD3/PPIH	84
MF	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	23/2603	60/17697	6.003e-06	0.001896	0.001685	NDUFC1/NDUFA13/NDUFS4/NDUFB4/NQO1/NDUFA4/NDUFA8/NDUFA2/NDUFB6/NDUFB7/NDUFB2/AKR1C3/CRYZ/NDUFA6/NDUFA10/NDUFB8/NDUFA3/NDUFS3/NDUFS7/NDUFS6/CBR1/AKR1C4/NDUFA1	23
MF	GO:0042277	peptide binding	72/2603	295/17697	6.628e-06	0.001896	0.001685	NFKBIA/TAP1/HLA-C/TRHDE/TREM2/SLC7A5/CLU/HLA-F/HLA-G/HLA-A/LILRB2/KDELR3/LRPAP1/PEX19/PTH1R/NUP153/KPNA2/PRNP/NPAP1/APOE/INSR/AP2M1/HLA-B/HLA-E/PPIC/IDE/RXRA/GSTM4/GSAP/PGRMC1/CMA1/TMEM158/PPARG/GPR1/PEX7/TAPBP/GRIA2/CRYAB/MAML1/NKTR/ADRB2/NPR2/CRHBP/ANG/GHSR/VIPR1/HCRTR2/TNPO1/ITM2C/EPHA4/HLA-DQB1/GSTM3/LNPEP/CALCR/NOD2/DHCR24/SEC61A2/KPNB1/PPP3CA/PPIE/SSTR5/SRP54/PPIB/NGFR/KPNA1/CCKAR/GHR/GALR3/KPNA3/ANPEP/NUP98/PPIH	72
MF	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	13/2603	25/17697	1.334e-05	0.003052	0.002713	BIRC3/SNCA/BIRC2/BIRC7/TNFAIP8/NOL3/LEF1/ARRB1/CD27/BIRC5/NAIP/TNFSF14/RPS6KA1	13
MF	GO:0019207	kinase regulator activity	53/2603	207/17697	2.623e-05	0.004579	0.00407	TOM1L1/CXCL10/GPRC5C/SOCS6/CCL5/PRKAR2A/MALT1/CCNA2/FGF13/CDKN2C/EGF/CCNL1/CKS1B/CDK4/SOCS1/PRKAG1/DBF4/MADD/EFNA5/WNT11/CSNK2B/CKS2/FGFR1OP/HSPB1/CCNT2/DAXX/TRIB1/CCNB2/CCNB1/CCNH/RAC2/TAOK1/ELP3/PIK3R5/CDKN1C/WDR91/ATG13/MLST8/DNAJC3/ABI1/CCNK/TAOK3/CIB1/RHOH/PAK2/CCND2/KAT2B/BCL10/CDKN1A/MNAT1/CISH/CCNL2/PIK3CA	53
MF	GO:0005543	phospholipid binding	94/2603	427/17697	2.802e-05	0.004579	0.00407	MICALL1/DYSF/GPAA1/SNX15/IQGAP2/TREM2/NME4/MREG/RASGRP1/PEMT/SNCA/DAPP1/SNX7/KCNQ1/PIGK/APOM/SYT11/PLA2G2D/ARFIP1/PLA2G15/ZCCHC2/SERPINA5/ZFYVE16/ATP8B1/BAD/GSDMB/FCHSD2/PFN2/ASAP1/RACGAP1/APOE/DGKA/SNX24/BIN1/ING2/PITPNC1/OSBPL8/SH3YL1/PLEKHA4/IGHM/PIK3C2B/PLA2G7/PCTP/DENND1B/PLD1/PLEKHA1/KCNJ2/SNX17/SYT17/FERMT2/KRIT1/PLA2G4C/ARAP3/APOC1/SNX2/ITPR2/PRKCI/CHMP2A/RAPGEF6/CPS1/AXL/ACAP2/DENND1C/SCIN/HMGB1/ARHGAP35/RS1/VAMP2/NRGN/PLCD1/SNX10/TPCN1/OGT/ANXA7/GSDMD/PXDC1/HIP1R/SYT1/GOLPH3/PIK3C2G/ANXA9/FZD7/NR5A2/STOML2/EXOC1/PSAP/MCF2L/CPNE6/ARHGAP26/ADAP2/PASK/RNF34/NUP62/NCF1	94
MF	GO:0003954	NADH dehydrogenase activity	18/2603	46/17697	4.4e-05	0.005034	0.004475	NDUFC1/NDUFA13/NDUFS4/NDUFB4/NDUFA4/NDUFA8/NDUFA2/NDUFB6/NDUFB7/NDUFB2/NDUFA6/NDUFA10/NDUFB8/NDUFA3/NDUFS3/NDUFS7/NDUFS6/NDUFA1	18
MF	GO:0008137	NADH dehydrogenase (ubiquinone) activity	18/2603	46/17697	4.4e-05	0.005034	0.004475	NDUFC1/NDUFA13/NDUFS4/NDUFB4/NDUFA4/NDUFA8/NDUFA2/NDUFB6/NDUFB7/NDUFB2/NDUFA6/NDUFA10/NDUFB8/NDUFA3/NDUFS3/NDUFS7/NDUFS6/NDUFA1	18
MF	GO:0050136	NADH dehydrogenase (quinone) activity	18/2603	46/17697	4.4e-05	0.005034	0.004475	NDUFC1/NDUFA13/NDUFS4/NDUFB4/NDUFA4/NDUFA8/NDUFA2/NDUFB6/NDUFB7/NDUFB2/NDUFA6/NDUFA10/NDUFB8/NDUFA3/NDUFS3/NDUFS7/NDUFS6/NDUFA1	18
MF	GO:0050662	coenzyme binding	68/2603	291/17697	5.22e-05	0.005199	0.004621	CBS/GCH1/P4HTM/CYB5R1/CRYL1/MICAL1/IVD/ILVBL/SDS/QDPR/THNSL2/LBR/ECI2/TYW1/GOT1/ALDH1A1/ACOX2/PNPO/ME2/HSD11B2/DDO/BDH2/PHYH/SUOX/HSD17B1/SORD/HMGCL/GCAT/COQ6/HPGD/PC/PYGM/CAT/MICAL2/HADH/SIRT3/ACAT1/HDC/DLD/NOS3/GMDS/SCP2/GRHPR/CRYZ/AHCY/ALDH1A3/OAT/DHCR24/EGLN3/FMO3/DHCR7/ACADM/NUDT6/SRR/ACOX1/AGPS/FMO4/SUV39H2/CYB5R3/DUS4L/PANK3/ALDH6A1/MDH1/SGPL1/TXNRD2/SIRT7/TH/ACBD3	68
MF	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	15/2603	35/17697	5.454e-05	0.005199	0.004621	AKR1B1/AKR1B10/ALDH7A1/ALDH1A1/DLD/ALDH9A1/AKR1C3/ALDH3A2/ALDH1A3/PDHB/FAR2/ALDH6A1/ALDH18A1/AKR1C4/ALDH3B1	15
MF	GO:0019887	protein kinase regulator activity	46/2603	180/17697	9.093e-05	0.008002	0.007112	TOM1L1/CXCL10/GPRC5C/CCL5/PRKAR2A/CCNA2/FGF13/CDKN2C/EGF/CCNL1/CKS1B/CDK4/SOCS1/PRKAG1/DBF4/MADD/EFNA5/WNT11/CSNK2B/CKS2/FGFR1OP/HSPB1/CCNT2/DAXX/TRIB1/CCNB2/CCNB1/CCNH/RAC2/TAOK1/ELP3/CDKN1C/ATG13/MLST8/DNAJC3/ABI1/CCNK/TAOK3/CIB1/PAK2/CCND2/KAT2B/CDKN1A/MNAT1/CCNL2/PIK3CA	46
MF	GO:0016651	oxidoreductase activity, acting on NAD(P)H	31/2603	107/17697	0.0001097	0.008963	0.007966	CYB5R1/MICAL1/NDUFC1/NDUFA13/NDUFS4/NDUFB4/NQO1/NDUFA4/NDUFA8/NDUFA2/MICAL2/NDUFB6/NDUFB7/DLD/NOS3/NDUFB2/AKR1C3/CRYZ/NDUFA6/NDUFA10/NDUFB8/NDUFA3/CYB5R3/NDUFS3/NDUFS7/NDUFS6/CBR1/TXNRD2/AKR1C4/NDUFA1/NCF1	31
MF	GO:0035257	nuclear hormone receptor binding	40/2603	152/17697	0.0001292	0.009808	0.008718	STAT1/TRIP6/SMAD3/PRKCB/MED13/NCOA3/TRIP12/NCOA6/SMARCD3/TADA3/PRAME/RXRA/MMS19/LEF1/MED1/PPARG/KDM3A/ARRB1/ARID1A/YWHAH/TAF10/DAXX/TAF7/BUD31/TRIM24/TACC2/KAT5/NCOR1/HIF1A/PADI2/RNF14/TCF7L2/FHL2/EP300/CRY1/ETS2/BAZ2A/CEBPB/HMGA1/NUP62	40
MF	GO:0004674	protein serine/threonine kinase activity	93/2603	439/17697	0.0001372	0.009808	0.008718	SIK1/SRPK1/IRAK3/CDC7/MAP3K5/PRKD2/GAK/MAPK3/RIPK2/STK19/TBK1/LIMK2/SNRK/PRKCB/TNIK/STK10/STK17B/ATR/CHEK2/CHEK1/ATM/DYRK4/EGFR/MAP3K11/PINK1/PIM1/PRKCH/PRKX/GSK3B/CDK4/PRKD3/PRPF4B/CDK18/MAPK7/PRKAG1/DYRK2/PRKAB1/BUB1B/CSNK2B/CDK8/PIM2/ROCK1/ALPK1/MAP4K1/MAP3K8/NEK3/FASTK/PLK2/CDK17/MAPK11/CHUK/PRKCI/CCNH/PSKH1/TAOK1/MAP4K4/VRK2/IRAK4/TOP1/MELK/CSNK1A1/AURKB/PRKCQ/CSNK1E/NLK/MAPKAPK2/MAP3K3/CAMK1/MKNK2/LTBP4/CCNK/ERCC2/PRKAA1/TAOK3/RAF1/AKAP13/GRK6/CDK20/CDK1/CDKL5/PAK2/MNAT1/MARK3/CLK1/RIOK3/RPS6KA1/GTF2H3/PTK2B/CDK9/CAMK2B/CAB39L/PASK/PIK3CA	93
MF	GO:0009055	electron transfer activity	32/2603	114/17697	0.0001646	0.01108	0.009846	AKR1B1/COX7A1/HAAO/QDPR/ETFB/SDHC/AKR7A3/DHRS3/NDUFA4L2/GLRX5/ME2/IDO1/NQO1/NDUFA4/UQCR10/FDX1/ASPH/CYC1/COX6C/COX8A/AKR7A2/COX6A1/SDHD/DLD/COX5B/UQCRQ/NDUFS3/NDUFS6/TXNRD2/AKR1C4/UQCRC1/NCF1	32
MF	GO:0004896	cytokine receptor activity	28/2603	96/17697	0.0002039	0.01296	0.01152	IL11RA/CSF2RB/IL15RA/CRLF1/IL21R/IL27RA/IL2RG/IL7R/IL4R/CX3CR1/GFRA1/CCR5/IL1RL2/CXCR4/CD44/IL2RB/IL17RB/CCR7/CXCR2/IL3RA/IL17RC/IL6R/GHR/IL13RA2/CCR2/IL17RA/EPOR/CXCR6	28
MF	GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	16/2603	43/17697	0.0002315	0.01394	0.01239	AKR1B1/AKR1B10/ALDH7A1/BCKDHB/ALDH1A1/DLD/ALDH9A1/AKR1C3/ALDH3A2/ALDH1A3/PDHB/FAR2/ALDH6A1/ALDH18A1/AKR1C4/ALDH3B1	16
MF	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	17/2603	49/17697	0.0003931	0.02249	0.01999	CCNA2/CDKN2C/CCNL1/CKS1B/CDK4/CKS2/CCNT2/CCNB2/CCNB1/CCNH/CDKN1C/CCNK/CCND2/KAT2B/CDKN1A/MNAT1/CCNL2	17
MF	GO:1901681	sulfur compound binding	56/2603	250/17697	0.0006983	0.03655	0.03249	CBS/SFRP1/CXCL10/PTN/NELL1/NDNF/GAL3ST4/ILVBL/ENPP1/CRISPLD2/LIPC/CXCL13/PGF/THBS4/ECI2/CXCL11/PLA2G2D/LRPAP1/PTPRF/PTPRC/PCOLCE/SERPINA5/APOE/APLP2/AAMP/HMGCL/BMP4/FGF20/GSTM4/PC/ELANE/POSTN/CCL8/CHST15/ZNF146/DLD/COMP/PCOLCE2/ANG/HBEGF/SCP2/GSTM3/VEGFA/ADAMTS3/COL5A3/LPL/SUV39H2/CTSG/THBS2/PANK3/ADAMTS8/CCL7/ALDH6A1/CHST12/ACBD3/VEGFB	56
MF	GO:0035091	phosphatidylinositol binding	55/2603	245/17697	0.0007338	0.03655	0.03249	GPAA1/SNX15/IQGAP2/MREG/DAPP1/SNX7/KCNQ1/PIGK/ARFIP1/ZCCHC2/ZFYVE16/GSDMB/FCHSD2/PFN2/ASAP1/RACGAP1/SNX24/ING2/PITPNC1/OSBPL8/SH3YL1/PLEKHA4/PIK3C2B/DENND1B/PLD1/PLEKHA1/KCNJ2/SNX17/FERMT2/KRIT1/ARAP3/SNX2/ITPR2/ACAP2/DENND1C/SCIN/RS1/NRGN/PLCD1/SNX10/TPCN1/OGT/GSDMD/PXDC1/HIP1R/SYT1/GOLPH3/PIK3C2G/FZD7/EXOC1/MCF2L/ADAP2/PASK/RNF34/NCF1	55
MF	GO:0005539	glycosaminoglycan binding	52/2603	229/17697	0.0007649	0.03655	0.03249	SFRP1/CXCL10/PTN/NELL1/TREM2/NDNF/EPYC/CRISPLD2/LIPC/CXCL13/PGF/THBS4/CXCL11/PLA2G2D/LRPAP1/PTPRF/PTPRC/PCOLCE/SERPINA5/PRNP/APOE/APLP2/AAMP/BMP4/IGHM/HMMR/CD44/ELANE/POSTN/CCL8/EXTL2/ZNF146/COMP/PCOLCE2/ANG/HAPLN1/HBEGF/VEGFA/NOD2/ADAMTS3/COL5A3/LTBP4/LPL/SPOCK2/NOD1/CTSG/THBS2/VCAN/ADAMTS8/CCL7/REG3A/VEGFB	52
MF	GO:0051287	NAD binding	18/2603	56/17697	0.0007668	0.03655	0.03249	CRYL1/QDPR/ALDH1A1/ME2/HSD11B2/BDH2/SORD/HPGD/HADH/SIRT3/DLD/GRHPR/AHCY/ALDH1A3/NUDT6/CYB5R3/MDH1/SIRT7	18
MF	GO:0042605	peptide antigen binding	12/2603	31/17697	0.0009196	0.04208	0.0374	TAP1/HLA-C/SLC7A5/HLA-F/HLA-G/HLA-A/HLA-B/HLA-E/TAPBP/MAML1/HLA-DQB1/DHCR24	12
MF	GO:0019209	kinase activator activity	24/2603	86/17697	0.001123	0.04915	0.04369	TOM1L1/GPRC5C/CCL5/MALT1/FGF13/EGF/CKS1B/DBF4/MADD/EFNA5/WNT11/CKS2/CCNT2/DAXX/CCNB1/TAOK1/MLST8/ABI1/CCNK/PAK2/BCL10/CDKN1A/MNAT1/PIK3CA	24
MF	GO:0032182	ubiquitin-like protein binding	26/2603	96/17697	0.00116	0.04915	0.04369	TNFAIP3/TOM1L1/FBXW7/SMAD3/UCHL1/TDG/CKS1B/BIRC2/USPL1/RNF111/TOLLIP/CXCR4/CKS2/HSPB1/DAXX/PML/RNF19B/CASP8AP2/UCHL3/TOP2A/IKBKG/UBE2L6/TRIM32/UBR5/DCUN1D1/NUP62	26
MF	GO:0016303	1-phosphatidylinositol-3-kinase activity	6/2603	10/17697	0.001239	0.04995	0.0444	ATM/PIK3C2B/PIK3CB/PIK3CD/PIK3C2G/PIK3CA	6
MF	GO:0051427	hormone receptor binding	43/2603	185/17697	0.001286	0.04995	0.0444	STAT1/JAK2/TRIP6/SMAD3/PRKCB/MED13/NCOA3/TRIP12/NCOA6/SMARCD3/TADA3/TYK2/PRAME/RXRA/JAK1/MMS19/LEF1/MED1/PPARG/KDM3A/ARRB1/ARID1A/YWHAH/TAF10/DAXX/TAF7/BUD31/TRIM24/TACC2/KAT5/NCOR1/HIF1A/PADI2/RNF14/TCF7L2/FHL2/EP300/CRY1/ETS2/BAZ2A/CEBPB/HMGA1/NUP62	43
MF	GO:0031625	ubiquitin protein ligase binding	62/2603	290/17697	0.00131	0.04995	0.0444	CBS/NFKBIA/SMC6/TNFRSF1B/UBE2D4/FBXW7/GABARAPL1/PRKAR2A/CLU/TRAF1/SMAD3/GABARAPL2/SYT11/ERLIN2/UCHL1/TRAF5/CHEK2/EGFR/UBE2J1/PINK1/SLC22A18/GSK3B/TNFRSF14/RALA/PRDX6/RRAGA/JAK1/DNAJA1/PTPN22/FHIT/TOLLIP/CD40/CXCR4/ARRB1/PRR5L/DAXX/TRIB1/ATF6/DET1/SNCAIP/PML/MFHAS1/UBB/GLMN/DIO2/TRAF3/BAG1/NLK/HIF1A/NGFR/IKBKG/UBE2L6/BCL10/CDKN1A/FZD6/CUL2/NEDD8/PTK2B/UQCRC1/HSPA5/GABARAP/RNF34	62
MF	GO:0003713	transcription coactivator activity	67/2603	319/17697	0.001393	0.0513	0.0456	NUPR1/CEBPA/KDM5A/PRKCB/PCBD1/FOXC1/MED13/NCOA3/SS18L1/NCOA6/SMARCD3/NFE2L3/PDLIM1/TADA3/RAP2C/BIRC2/RXRA/RRP1B/MMS19/TCERG1/MED1/PPARG/JMJD6/ARID1A/MAML1/DAXX/DCAF6/ZFPM2/HCFC2/GTF2A2/ATF6/TFEC/NR1H2/CD3D/PML/TAF7/BUD31/TRIM24/ARL2BP/MTDH/NR2F1/HMGB1/MED23/MAGED1/MED7/KAT6A/KAT5/SMARCD2/SIX3/TCF3/MED27/RNF14/NPAT/KAT2B/BCL10/FHL2/EP300/TRIM32/ACTN1/PPRC1/LPIN1/NFYC/USP21/NUP98/HMGA1/NRL/NR1D2	67
MF	GO:0044389	ubiquitin-like protein ligase binding	65/2603	308/17697	0.001435	0.0513	0.0456	CBS/NFKBIA/SMC6/STAT1/TNFRSF1B/UBE2D4/FBXW7/GABARAPL1/PRKAR2A/CLU/TRAF1/SMAD3/GABARAPL2/SYT11/ERLIN2/UCHL1/TRAF5/CHEK2/EGFR/UBE2J1/PINK1/SLC22A18/GSK3B/TNFRSF14/RALA/PRDX6/RRAGA/JAK1/DNAJA1/PTPN22/FHIT/TOLLIP/CD40/CXCR4/ARRB1/PRR5L/DAXX/TRIB1/ATF6/DET1/CCNB1/SNCAIP/PML/MFHAS1/UBB/GLMN/DIO2/TRAF3/BAG1/NLK/HIF1A/NGFR/IKBKG/UBE2L6/BCL10/CDKN1A/FZD6/CUL2/NEDD8/PTK2B/CEBPB/UQCRC1/HSPA5/GABARAP/RNF34	65
MF	GO:0016887	ATPase activity	78/2603	384/17697	0.001617	0.05557	0.04939	TAP1/ATP1B1/CD320/SMCHD1/ATP2A3/DNAL4/CHD8/ATP6V0D1/MACF1/ATP13A3/ABCC10/ATF7IP/ABCC4/ABCA8/DNA2/KIF2A/ATP2C1/DDX39A/PFN2/ATAD2B/ABCA3/IDE/DDX11/PSMC2/TAPBP/TCIRG1/KIF18B/KIF5C/CENPE/ATP2B2/KIF11/AK6/ABCC1/CCNH/MDN1/PSMC3/DYNC1I1/HSPA6/KIF4A/KIF15/ABCA2/ATRX/ATP8A1/DYNC1H1/PMS2P1/PBRM1/TAP2/ATP6V0E2/RAD51C/ABCC8/YTHDC2/TOP2A/ABCA11P/CHD3/RUVBL2/ABCB1/WRN/SPAST/KATNB1/SMARCA5/ERCC2/MYH4/ABCF1/ATP2B4/BPTF/LMBRD1/ATAD2/MNAT1/HSPA2/KIF20A/GTF2H3/YME1L1/RFC2/HSPA5/MYH10/RAD51B/ATP2B1/DYNC2LI1	78
MF	GO:0004715	non-membrane spanning protein tyrosine kinase activity	15/2603	46/17697	0.001749	0.05557	0.04939	JAK2/RIPK2/ITK/TYK2/JAK1/FGR/ZAP70/LCK/TXK/MELK/MATK/TNK1/WEE1/CLK1/PTK2B	15
MF	GO:0005048	signal sequence binding	15/2603	46/17697	0.001749	0.05557	0.04939	NFKBIA/KDELR3/PEX19/NUP153/KPNA2/NPAP1/AP2M1/PEX7/TNPO1/SEC61A2/KPNB1/SRP54/KPNA1/KPNA3/NUP98	15
MF	GO:0032813	tumor necrosis factor receptor superfamily binding	15/2603	46/17697	0.001749	0.05557	0.04939	STAT1/TRAF1/TRAF5/CFLAR/SIVA1/MADD/NOL3/TRAP1/CASP8AP2/TNFSF4/TRAF3/TNFSF8/TNFSF14/MYD88/CD40LG	15
MF	GO:0030295	protein kinase activator activity	22/2603	80/17697	0.002174	0.06722	0.05975	TOM1L1/GPRC5C/CCL5/FGF13/EGF/CKS1B/DBF4/MADD/EFNA5/WNT11/CKS2/CCNT2/DAXX/CCNB1/TAOK1/MLST8/ABI1/CCNK/PAK2/CDKN1A/MNAT1/PIK3CA	22
MF	GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	8/2603	18/17697	0.00238	0.07002	0.06223	CDK8/CCNH/CCNK/ERCC2/CDK1/MNAT1/GTF2H3/CDK9	8
MF	GO:0035004	phosphatidylinositol 3-kinase activity	6/2603	11/17697	0.002387	0.07002	0.06223	ATM/PIK3C2B/PIK3CB/PIK3CD/PIK3C2G/PIK3CA	6
MF	GO:0005126	cytokine receptor binding	60/2603	286/17697	0.002462	0.07042	0.06259	CXCL9/CXCL10/STAT1/JAK2/CCL5/CRLF1/CXCL13/PGF/TRIP6/CCL18/TRAF1/SMAD3/IL15/CXCL11/TRAF5/CFLAR/ADAM17/SIVA1/ITGA5/TYK2/NTF3/CXCL2/BMP4/GDF5/MADD/EFNA5/NOL3/JAK1/PXDN/CTF1/TOLLIP/NTRK1/CCL8/CDH5/IFNG/IL6/TLR5/IRAK4/XCL1/TRAP1/VEGFA/CASP8AP2/TNFSF4/CXCL3/TRAF3/CCL13/TNFSF8/IL1RN/GDF9/IL6R/TNFSF14/CCL7/MYD88/SH2B3/INHBB/CXCL8/CCR2/CD40LG/IL22/VEGFB	60
MF	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	13/2603	39/17697	0.002794	0.07633	0.06785	IQGAP2/DAPP1/ZFYVE16/FCHSD2/ASAP1/RACGAP1/FERMT2/ARAP3/RS1/NRGN/OGT/HIP1R/ADAP2	13
MF	GO:1990841	promoter-specific chromatin binding	15/2603	48/17697	0.002802	0.07633	0.06785	STAT1/SUZ12/DNMT1/FOXC1/EZH2/USP3/PCGF1/EGR1/PRDM1/NFE2L1/WDR13/HDAC1/NUP98/NRL/RBL2	15
MF	GO:0031406	carboxylic acid binding	43/2603	193/17697	0.003035	0.07877	0.07002	GCHFR/P4HTM/FOLR1/THNSL2/ALOX5AP/DDAH1/GOT1/ACOX2/UBR2/SERPINA5/PHYH/DPYS/HMGCL/RXRA/SELE/HMMR/PPARG/PC/CD44/FOLR2/DDAH2/APOC1/ASS1/NOS3/HAPLN1/SCP2/GRHPR/CPS1/PTGDS/EGLN3/CYP4F11/SRR/ACOX1/TYMS/ID3/FCN1/VCAN/ST8SIA2/SESN1/FABP3/SLC1A1/PSAP/TH	43
MF	GO:0019205	nucleobase-containing compound kinase activity	14/2603	44/17697	0.003182	0.07877	0.07002	NME4/TK2/NME7/NME5/ADK/DGUOK/NME3/AK1/AK6/GUK1/RAD50/SUCLG1/MPP1/TJP2	14
MF	GO:0004713	protein tyrosine kinase activity	32/2603	134/17697	0.003229	0.07877	0.07002	EFEMP1/JAK2/RIPK2/ITK/DYRK4/EGFR/MERTK/NTRK2/INSR/TYK2/KIT/DYRK2/ERBB2/JAK1/FGR/TIE1/ZAP70/EPHB6/NTRK1/LCK/KDR/TXK/AXL/EPHA4/MELK/MATK/TNK1/TYRO3/WEE1/ERBB4/CLK1/PTK2B	32
MF	GO:0004869	cysteine-type endopeptidase inhibitor activity	17/2603	58/17697	0.003236	0.07877	0.07002	BIRC3/SNCA/SPOCK1/PTTG1/BIRC2/BIRC7/TNFAIP8/NOL3/LEF1/ARRB1/CD27/BIRC5/CST7/NAIP/TNFSF14/CST4/RPS6KA1	17
MF	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	17/2603	58/17697	0.003236	0.07877	0.07002	IVD/TBXAS1/LBR/SDHC/ACOX2/TECR/DECR2/MECR/BDH2/SDHD/AKR1C3/DHCR24/DHCR7/ACADM/ACOX1/DUS4L/CPOX	17
MF	GO:0017124	SH3 domain binding	31/2603	130/17697	0.003793	0.09039	0.08034	TOM1L1/MICAL1/ADAM19/SH3GL1/SOS1/ADAM17/KHDRBS3/SH2D2A/SYNJ1/PTTG1/UVRAG/PTPN22/GPX1/CBLB/CD3E/WIPF1/TP53BP2/PLSCR4/CASP9/USP8/FUT8/ABI1/DOCK3/RUFY2/RAD9A/HIP1R/SH3BGR/EFS/PTTG2/SH3BGRL/NCF1	31
MF	GO:0001618	virus receptor activity	20/2603	74/17697	0.004196	0.0956	0.08497	TFRC/SLAMF1/EGFR/SIVA1/ITGA5/TNFRSF14/IDE/CCR5/ITGB7/CXCR4/CD81/CR1/AXL/ITGB5/CDK1/TYRO3/SLC20A2/CXADR/ANPEP/NPC1	20
MF	GO:0104005	hijacked molecular function	20/2603	74/17697	0.004196	0.0956	0.08497	TFRC/SLAMF1/EGFR/SIVA1/ITGA5/TNFRSF14/IDE/CCR5/ITGB7/CXCR4/CD81/CR1/AXL/ITGB5/CDK1/TYRO3/SLC20A2/CXADR/ANPEP/NPC1	20
MF	GO:0008201	heparin binding	38/2603	169/17697	0.004341	0.0956	0.08497	SFRP1/CXCL10/PTN/NELL1/NDNF/CRISPLD2/LIPC/CXCL13/PGF/THBS4/CXCL11/PLA2G2D/LRPAP1/PTPRF/PTPRC/PCOLCE/SERPINA5/APOE/APLP2/AAMP/BMP4/ELANE/POSTN/CCL8/ZNF146/COMP/PCOLCE2/ANG/HBEGF/VEGFA/ADAMTS3/COL5A3/LPL/CTSG/THBS2/ADAMTS8/CCL7/VEGFB	38
MF	GO:0061134	peptidase regulator activity	47/2603	219/17697	0.004345	0.0956	0.08497	BIRC3/PROS1/SNCA/SLPI/SERPINA3/CFLAR/SPOCK1/SERPINA1/PCOLCE/SERPINA5/BAD/NLRP1/PTTG1/PINK1/TIMP2/SERPINE1/CARD8/APLP2/BIRC2/BIRC7/ITIH4/SERPINB6/TNFAIP8/NOL3/LEF1/TFPI/ARRB1/CD27/APAF1/AGT/PCOLCE2/SERPINA4/CASP8AP2/TIMP4/BIRC5/CST7/NAIP/COL6A3/SPOCK2/NOD1/TNFSF14/TIMP1/FBLN1/CST4/RPS6KA1/SERPINF1/USP14	47
MF	GO:0032183	SUMO binding	7/2603	16/17697	0.004976	0.1044	0.0928	TDG/USPL1/RNF111/TOLLIP/DAXX/PML/CASP8AP2	7
MF	GO:0050700	CARD domain binding	7/2603	16/17697	0.004976	0.1044	0.0928	RIPK2/CARD8/CASP4/CARD14/NOD2/NOD1/BCL10	7
MF	GO:0008022	protein C-terminus binding	41/2603	187/17697	0.00502	0.1044	0.0928	ATP1B1/TOPBP1/JAK2/CEP135/IFT46/ERCC1/FBLN5/NIPBL/SH3GL1/SDC1/BAIAP2/IFT52/MKI67/ERBB2/MAPRE3/KCNK3/PPARG/PHB/SNX17/PFKM/LCK/PCGF1/BANF1/BRCA2/CDC20/TOP2A/PEX12/OPTN/ERCC2/PRKAA1/CIB1/SLC9A3R2/NPAT/BCL10/SYT1/FBLN1/EP300/KPNA3/PTK2B/ATF4/CENPF	41
MF	GO:0017147	Wnt-protein binding	12/2603	37/17697	0.005161	0.1054	0.09371	WIF1/SFRP1/EGF/MERTK/FZD3/WLS/LRP5/AXL/TYRO3/FZD6/FZD7/FZD2	12
MF	GO:0043177	organic acid binding	44/2603	205/17697	0.005638	0.1099	0.0977	GCHFR/P4HTM/FOLR1/THNSL2/ALOX5AP/DDAH1/GOT1/ACOX2/UBR2/SERPINA5/PHYH/DPYS/HMGCL/RXRA/SELE/HMMR/PPARG/PC/CD44/FOLR2/DDAH2/APOC1/ASS1/NOS3/HAPLN1/SCP2/GRHPR/CPS1/PTGDS/EGLN3/CYP4F11/HBB/SRR/ACOX1/TYMS/ID3/FCN1/VCAN/ST8SIA2/SESN1/FABP3/SLC1A1/PSAP/TH	44
MF	GO:0002020	protease binding	30/2603	128/17697	0.005669	0.1099	0.0977	TNFAIP3/RIPK2/SRI/MALT1/CFLAR/CRADD/SERPINA1/SERPINA5/PRNP/PINK1/TIMP2/SERPINE1/GSK3B/SART3/KIT/BIN1/SERPINB6/NOL3/CD28/ELANE/POLG/COMP/BRCA2/TIMP4/NDUFS7/BCL10/TIMP1/COL3A1/RIOK3/PSAP	30
MF	GO:0019955	cytokine binding	30/2603	128/17697	0.005669	0.1099	0.0977	GBP1/IL11RA/TNFRSF1B/CRLF1/IL27RA/IL2RG/LTBP3/CX3CR1/TNFRSF11A/TNFRSF14/KIT/CCR5/GDF5/PXDN/CXCR4/ELANE/COMP/NBL1/IL2RB/HMGB1/CCR7/CXCR2/IL3RA/LTBP4/IL1RN/IL6R/GHR/IL13RA2/CCR2/CXCR6	30
MF	GO:1901981	phosphatidylinositol phosphate binding	36/2603	161/17697	0.00592	0.1129	0.1003	IQGAP2/DAPP1/KCNQ1/ARFIP1/ZFYVE16/GSDMB/FCHSD2/PFN2/ASAP1/RACGAP1/SNX24/OSBPL8/PLEKHA4/DENND1B/PLEKHA1/KCNJ2/FERMT2/KRIT1/ARAP3/ACAP2/DENND1C/SCIN/RS1/NRGN/PLCD1/TPCN1/OGT/GSDMD/HIP1R/SYT1/GOLPH3/FZD7/EXOC1/ADAP2/RNF34/NCF1	36
MF	GO:0019903	protein phosphatase binding	32/2603	140/17697	0.0065	0.1209	0.1074	SPHK1/STAT1/CDH2/PPP1R3C/MAP3K5/TBK1/KCNQ1/LILRB2/MTMR4/MTMR9/BAD/EGFR/PPP6R3/ERBB2/JAK1/PDLIM4/FBXL2/PPARG/SHOC2/CDH5/LCK/MFHAS1/TRAF3/ANKLE2/SOD1/PHACTR4/ATP2B4/ENSA/LGALS3/MVP/STYXL1/STAU1	32
MF	GO:0042056	chemoattractant activity	12/2603	38/17697	0.006551	0.1209	0.1074	CXCL10/CCL5/PGF/HGF/NTF3/BMP4/PDGFB/VEGFA/HMGB1/SCG2/LGALS3/VEGFB	12
MF	GO:0008139	nuclear localization sequence binding	9/2603	25/17697	0.006964	0.1263	0.1122	NFKBIA/NUP153/KPNA2/NPAP1/TNPO1/KPNB1/KPNA1/KPNA3/NUP98	9
MF	GO:0019902	phosphatase binding	40/2603	185/17697	0.007064	0.1263	0.1122	SPHK1/STAT1/CDH2/PPP1R3C/MAP3K5/MAPK3/TBK1/SMAD3/KCNQ1/SH3GL1/LILRB2/MTMR4/MTMR9/BAD/EGFR/PPP6R3/ERBB2/JAK1/SH3YL1/MAGI2/PDLIM4/SFI1/FBXL2/PPARG/SHOC2/CDH5/LCK/MFHAS1/TRAF3/ANKLE2/SOD1/PHACTR4/ATP2B4/SLC9A3R2/ENSA/LGALS3/CRY1/MVP/STYXL1/STAU1	40
MF	GO:0004602	glutathione peroxidase activity	8/2603	21/17697	0.007352	0.127	0.1129	LTC4S/ALOX5AP/GPX3/PRDX6/MGST3/GSTZ1/GPX1/GPX4	8
MF	GO:0035173	histone kinase activity	7/2603	17/17697	0.007398	0.127	0.1129	JAK2/PRKCB/CHEK1/CCNB1/AURKB/PRKAA1/CDK1	7
MF	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	11/2603	34/17697	0.007439	0.127	0.1129	STAT1/EZH2/MED1/ZNF451/KDM3A/POU2F1/RUVBL2/HDAC1/PRDM10/CEBPB/POGZ	11
MF	GO:0015631	tubulin binding	66/2603	336/17697	0.007751	0.1304	0.1159	BEX4/DYSF/CETN2/GPAA1/ARL4C/CEP350/STMN2/UNC5C/ARL3/GABARAPL1/SNCA/NDE1/MACF1/GABARAPL2/SYT11/MDM1/FGF13/CCDC88C/HSPH1/AGTPBP1/KIF2A/NDN/PRNP/RACGAP1/TPR/MAPRE3/NUSAP1/SPAG5/ARHGEF2/MAP7D3/TTLL4/BBS4/CRYAB/KIF18B/DRG1/PRC1/KRIT1/EML1/KIF5C/CENPE/KIF11/DYNC1I1/TAOK1/MAP4K4/KIF4A/BRCA2/CLASP1/KIF15/TUBGCP5/CCDC181/RITA1/BIRC5/AGBL5/MTUS2/PEX14/SPAST/KATNB1/SETD2/HOOK2/MAPRE2/EML4/KIF20A/VAPA/OFD1/TUBGCP2/GABARAP	66
MF	GO:0016776	phosphotransferase activity, phosphate group as acceptor	12/2603	39/17697	0.008222	0.1363	0.1212	NME4/NME7/PMVK/NME5/NME3/AK1/AK6/GUK1/RAD50/SUCLG1/MPP1/TJP2	12
MF	GO:0097472	cyclin-dependent protein kinase activity	10/2603	30/17697	0.008367	0.1367	0.1215	CCNA2/CDK4/CDK18/CDK8/CDK17/CCNK/CDK20/CDK1/CDKL5/CDK9	10
MF	GO:0005178	integrin binding	30/2603	132/17697	0.008927	0.1435	0.1276	PTN/LCP1/FBLN5/THBS4/ITGBL1/ADAM17/EGFR/ITGA5/ADAM23/TIMP2/ITGB7/TSPAN4/LAMA5/ADAM22/PTPN2/CD81/IGF1/COMP/KDR/CD151/HMGB1/LTBP4/EMP2/ANXA7/ITGB5/CXADR/ADAMTS8/COL3A1/ACTN1/ICAM3	30
MF	GO:0005388	calcium-transporting ATPase activity	5/2603	10/17697	0.009054	0.1435	0.1276	ATP2A3/ATP2C1/ATP2B2/ATP2B4/ATP2B1	5
MF	GO:0004709	MAP kinase kinase kinase activity	9/2603	26/17697	0.009285	0.1435	0.1276	MAP3K5/RIPK2/EGFR/MAP3K11/MAP3K8/TAOK1/MAP3K3/TAOK3/RAF1	9
MF	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	9/2603	26/17697	0.009285	0.1435	0.1276	TBXAS1/LBR/TECR/DECR2/MECR/BDH2/AKR1C3/DHCR24/DHCR7	9
MF	GO:0070403	NAD+ binding	6/2603	14/17697	0.01045	0.1584	0.1408	CRYL1/HPGD/HADH/SIRT3/ALDH1A3/SIRT7	6
MF	GO:0048156	tau protein binding	13/2603	45/17697	0.01073	0.1584	0.1408	LGMN/SNCA/CLU/APOE/GSK3B/BIN1/ROCK1/TAOK1/PIN1/PRKAA1/EP300/MARK3/HSPA2	13
MF	GO:0005164	tumor necrosis factor receptor binding	10/2603	31/17697	0.01076	0.1584	0.1408	STAT1/TRAF1/TRAF5/SIVA1/TRAP1/TNFSF4/TRAF3/TNFSF8/TNFSF14/CD40LG	10
MF	GO:0003725	double-stranded RNA binding	19/2603	75/17697	0.0108	0.1584	0.1408	TFRC/ADAR/LRRFIP1/RFTN1/RC3H2/PRKRA/MTDH/ZFR2/DDX1/ADARB2/AGO3/DDX60/MYH4/DDX21/OAS2/ACTN1/STAU2/TLR8/STAU1	19
MF	GO:0030165	PDZ domain binding	21/2603	86/17697	0.01172	0.1698	0.1509	SNTA1/DAPP1/SLC22A4/ADAM17/CCDC88C/BAIAP2/GNG12/PLEKHA1/FZD3/LIN7B/ATP2B2/LLGL2/CXXC4/SRR/ACOX1/ATP2B4/CXADR/SNTB1/FZD7/ATP2B1/FZD2	21
MF	GO:0004364	glutathione transferase activity	9/2603	27/17697	0.01215	0.1737	0.1544	HPGDS/LTC4S/GSTA4/ALOX5AP/MGST3/GSTM4/GSTZ1/GSTM5/GSTM3	9
MF	GO:0042623	ATPase activity, coupled	56/2603	284/17697	0.01235	0.1739	0.1546	TAP1/ATP1B1/CD320/ATP2A3/DNAL4/CHD8/ATP6V0D1/ABCC10/ABCC4/ABCA8/DNA2/ATP2C1/ABCA3/DDX11/PSMC2/TAPBP/TCIRG1/KIF18B/KIF5C/ATP2B2/KIF11/ABCC1/CCNH/DYNC1I1/HSPA6/ABCA2/ATRX/ATP8A1/DYNC1H1/PBRM1/TAP2/ATP6V0E2/RAD51C/ABCC8/YTHDC2/TOP2A/ABCA11P/CHD3/ABCB1/SPAST/KATNB1/SMARCA5/ERCC2/ATP2B4/BPTF/LMBRD1/MNAT1/HSPA2/GTF2H3/YME1L1/RFC2/HSPA5/MYH10/RAD51B/ATP2B1/DYNC2LI1	56
MF	GO:0043130	ubiquitin binding	19/2603	76/17697	0.01247	0.1739	0.1546	TNFAIP3/TOM1L1/FBXW7/SMAD3/UCHL1/CKS1B/BIRC2/TOLLIP/CXCR4/CKS2/HSPB1/RNF19B/UCHL3/TOP2A/IKBKG/UBE2L6/TRIM32/UBR5/NUP62	19
MF	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	15/2603	56/17697	0.01328	0.1831	0.1627	LTC4S/PTGS1/ALOX5AP/GPX3/PRDX6/MGST3/GSTZ1/PXDN/GPX1/CAT/GPX4/IPCEF1/HBB/PRDX2/SESN1	15
MF	GO:0071949	FAD binding	10/2603	32/17697	0.01363	0.1856	0.165	CYB5R1/MICAL1/ACOX2/DDO/COQ6/MICAL2/DHCR24/ACOX1/AGPS/CYB5R3	10
MF	GO:0008013	beta-catenin binding	20/2603	82/17697	0.01386	0.1866	0.1658	AR/CDH2/SOX9/CHD8/SKP1/SMAD3/RORA/CBY1/TCF7/CTNNBIP1/GSK3B/LEF1/CDH5/PIN1/RUVBL2/PTPRK/SLC9A3R2/TCF7L2/CXADR/EP300	20
MF	GO:0001055	RNA polymerase II activity	5/2603	11/17697	0.01461	0.1872	0.1664	POLR2J/POLR2L/POLR2E/POLR2F/POLR2C	5
MF	GO:0016801	hydrolase activity, acting on ether bonds	5/2603	11/17697	0.01461	0.1872	0.1664	EPHX1/EPHX2/AKR7A2/AHCY/RNPEP	5
MF	GO:0045236	CXCR chemokine receptor binding	5/2603	11/17697	0.01461	0.1872	0.1664	CXCL9/CXCL10/CXCL13/CXCL11/CXCL8	5
MF	GO:0043014	alpha-tubulin binding	11/2603	37/17697	0.01464	0.1872	0.1664	BEX4/DYSF/ARL4C/SNCA/HSPH1/RACGAP1/BBS4/TAOK1/SPAST/SETD2/OFD1	11
MF	GO:0019838	growth factor binding	30/2603	137/17697	0.01502	0.1872	0.1664	KAZALD1/IL11RA/PTN/IGFBP5/IGFBP2/CXCL13/IL2RG/S100A13/EGFR/LTBP3/NTRK2/INSR/IGFBP4/HTRA1/ERBB2/FIBP/PXDN/NTRK1/KDR/IL2RB/PDGFB/SORT1/LTBP4/IL1RN/NGFR/IL6R/RHBDF2/GHR/COL4A1/COL3A1	30
MF	GO:0004029	aldehyde dehydrogenase (NAD) activity	6/2603	15/17697	0.01528	0.1872	0.1664	ALDH7A1/ALDH1A1/ALDH9A1/ALDH3A2/ALDH1A3/ALDH3B1	6
MF	GO:0015269	calcium-activated potassium channel activity	6/2603	15/17697	0.01528	0.1872	0.1664	KCNN3/MTMR6/PKD2L1/KCNN2/CCT8L2/KCNMB2	6
MF	GO:1990404	protein ADP-ribosylase activity	6/2603	15/17697	0.01528	0.1872	0.1664	PARP12/PARP3/TNKS2/PARP6/PARP8/PARP4	6
MF	GO:0004601	peroxidase activity	14/2603	52/17697	0.01571	0.1872	0.1664	LTC4S/PTGS1/ALOX5AP/GPX3/PRDX6/MGST3/GSTZ1/PXDN/GPX1/CAT/GPX4/IPCEF1/HBB/PRDX2	14
MF	GO:0005070	SH3/SH2 adaptor activity	14/2603	52/17697	0.01571	0.1872	0.1664	SH2B2/ITSN2/SH2D2A/NCK2/CHN1/CD28/GRB10/SHB/TP53BP2/LAT/SH2B3/SH3BGR/SH3BGRL/SORBS1	14
MF	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	23/2603	99/17697	0.01571	0.1872	0.1664	HIVEP1/ZNF281/REL/BACH1/HOXB6/NFKB1/RELB/HOXB5/SFPQ/RUVBL2/NFE2L1/HOXA5/HDAC1/SMARCD2/SIX3/CREB1/ATF2/HOXA7/NR5A2/ATF4/NFYC/PBX3/NR1D2	23
MF	GO:0072341	modified amino acid binding	21/2603	89/17697	0.0172	0.2011	0.1787	CBS/FOLR1/RASGRP1/SYT11/GSDMB/ASAP1/GSTM4/OSBPL8/SYT17/FOLR2/CPS1/AXL/GSTM3/SCIN/HMGB1/RS1/GSDMD/TYMS/SYT1/ANXA9/CPNE6	21
MF	GO:0035326	enhancer binding	29/2603	133/17697	0.01754	0.2011	0.1787	SOX9/SMAD3/HIVEP1/ZNF281/REL/BACH1/HOXB6/LEF1/NFKB1/RELB/HOXB5/SFPQ/RUVBL2/NFE2L1/HOXA5/HDAC1/SMARCD2/SIX3/TCF3/CREB1/ATF2/XBP1/HOXA7/NR5A2/ATF4/NFYC/PBX3/HMGA1/NR1D2	29
MF	GO:0008198	ferrous iron binding	8/2603	24/17697	0.01771	0.2011	0.1787	HAAO/FECH/SNCA/FTO/PHYH/FTL/DNAJC24/TH	8
MF	GO:0140097	catalytic activity, acting on DNA	43/2603	213/17697	0.01772	0.2011	0.1787	SETX/DNASE1L3/CHD1/DCLRE1C/ERCC1/CHD8/NBN/POLD2/RECQL/DNMT1/FTO/DNASE1L1/DNA2/TDG/DDX11/POLD4/ISG20/SETMAR/TATDN2/MPG/GINS1/ASCC3/POLG/TOP1/ATRX/METTL4/DNASE2/PBRM1/RAD51C/RAD50/TOP2A/RAD1/CHD3/TDP1/RUVBL2/WRN/DDX1/ERCC2/DFFB/RAD9A/RFC2/HMGA1/HMGA2	43
MF	GO:0016504	peptidase activator activity	11/2603	38/17697	0.01793	0.2011	0.1787	CFLAR/PCOLCE/BAD/NLRP1/PINK1/CARD8/APAF1/PCOLCE2/CASP8AP2/NOD1/FBLN1	11
MF	GO:0048487	beta-tubulin binding	11/2603	38/17697	0.01793	0.2011	0.1787	GABARAPL1/SNCA/GABARAPL2/SYT11/FGF13/RACGAP1/BBS4/TAOK1/PEX14/SPAST/GABARAP	11
MF	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	15/2603	58/17697	0.0183	0.2033	0.1807	HPGDS/CBS/LTC4S/GSTA4/ALOX5AP/SMS/MGST3/GSTM4/GSTZ1/GSTM5/GSTM3/DHDDS/SRM/AGPS/COQ2	15
MF	GO:0042393	histone binding	40/2603	197/17697	0.01973	0.2086	0.1854	MTF2/STAT1/JAK2/KDM5A/CHD1/SUZ12/CHD8/SNCA/PRKCB/NAP1L2/USP3/CKS1B/ATAD2B/SART3/MSL3/SET/ING2/LEF1/KDM7A/DEK/CKS2/MLLT10/PHIP/DAXX/WDTC1/WDR5B/NASP/TAF7/ATRX/TRIM24/HJURP/KAT6A/KAT5/PTMA/SMARCA5/YEATS2/MBTD1/NPM3/ATAD2/BAZ2A	40
MF	GO:0004693	cyclin-dependent protein serine/threonine kinase activity	9/2603	29/17697	0.01976	0.2086	0.1854	CDK4/CDK18/CDK8/CDK17/CCNK/CDK20/CDK1/CDKL5/CDK9	9
MF	GO:0046966	thyroid hormone receptor binding	9/2603	29/17697	0.01976	0.2086	0.1854	TRIP6/MED13/NCOA3/TRIP12/NCOA6/MED1/TAF7/NCOR1/NUP62	9
MF	GO:0008301	DNA binding, bending	7/2603	20/17697	0.01977	0.2086	0.1854	FOXC1/LEF1/HMGB3/HMGB1/TOP2A/CEBPG/HMGA2	7
MF	GO:0016922	nuclear receptor binding	7/2603	20/17697	0.01977	0.2086	0.1854	NCOA3/TADA3/RXRA/MED1/ARID1A/TRIM24/BAZ2A	7
MF	GO:0005504	fatty acid binding	10/2603	34/17697	0.02104	0.2086	0.1854	ALOX5AP/ACOX2/PPARG/APOC1/SCP2/PTGDS/CYP4F11/ACOX1/ID3/FABP3	10
MF	GO:0005507	copper ion binding	15/2603	59/17697	0.0213	0.2086	0.1854	SNCA/S100A13/PRNP/SCO2/MOXD1/F8/ANG/P2RX4/PRND/CP/S100A5/SOD1/DCT/S100A12/CUTC	15
MF	GO:0004697	protein kinase C activity	6/2603	16/17697	0.02146	0.2086	0.1854	PRKD2/PRKCB/PRKCH/PRKD3/PRKCI/PRKCQ	6
MF	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	6/2603	16/17697	0.02146	0.2086	0.1854	BAD/NLRP1/CARD8/APAF1/CASP8AP2/NOD1	6
MF	GO:0016307	phosphatidylinositol phosphate kinase activity	6/2603	16/17697	0.02146	0.2086	0.1854	PIKFYVE/PIK3C2B/PIK3CB/PIK3CD/PIK3C2G/PIK3CA	6
MF	GO:0043395	heparan sulfate proteoglycan binding	6/2603	16/17697	0.02146	0.2086	0.1854	PLA2G2D/PTPRC/APOE/FGF20/COMP/LPL	6
MF	GO:0052742	phosphatidylinositol kinase activity	6/2603	16/17697	0.02146	0.2086	0.1854	ATM/PIK3C2B/PIK3CB/PIK3CD/PIK3C2G/PIK3CA	6
MF	GO:0004866	endopeptidase inhibitor activity	36/2603	175/17697	0.02153	0.2086	0.1854	BIRC3/PROS1/SNCA/SLPI/SERPINA3/SPOCK1/SERPINA1/SERPINA5/PTTG1/TIMP2/SERPINE1/APLP2/BIRC2/BIRC7/ITIH4/SERPINB6/TNFAIP8/NOL3/LEF1/TFPI/ARRB1/CD27/AGT/SERPINA4/TIMP4/BIRC5/CST7/NAIP/COL6A3/SPOCK2/TNFSF14/TIMP1/CST4/RPS6KA1/SERPINF1/USP14	36
MF	GO:0003697	single-stranded DNA binding	25/2603	113/17697	0.02199	0.2086	0.1854	SSBP2/ERCC1/HNRNPA2B1/POLR3C/RPA1/DDX11/SAMHD1/IGHM/RPA3/HNRNPK/RNF138/SETMAR/PCBP3/BRCA2/POLR2G/TOP1/HNRNPA1/HMGB1/RAD50/TDP1/NABP2/SMC4/TSN/YBX1/RAD51B	25
MF	GO:0008238	exopeptidase activity	25/2603	113/17697	0.02199	0.2086	0.1854	TRHDE/CPA3/PREPL/LAP3/UCHL1/METAP1/CTSA/PEPD/AGTPBP1/NAALAD2/ASRGL1/CPD/SCRN1/GGH/CPQ/LNPEP/CPE/AGBL5/RNPEP/TPP2/METAP2/ANPEP/DPP8/PRSS16/PREP	25
MF	GO:0008009	chemokine activity	13/2603	49/17697	0.022	0.2086	0.1854	CXCL9/CXCL10/CCL5/CXCL13/CCL18/CXCL11/CXCL2/CCL8/XCL1/CXCL3/CCL13/CCL7/CXCL8	13
MF	GO:0001054	RNA polymerase I activity	5/2603	12/17697	0.02206	0.2086	0.1854	POLR2L/POLR2E/POLR2F/POLR1B/POLR1C	5
MF	GO:0043047	single-stranded telomeric DNA binding	5/2603	12/17697	0.02206	0.2086	0.1854	HNRNPA2B1/RPA1/HNRNPA1/RAD50/NABP2	5
MF	GO:0016829	lyase activity	38/2603	187/17697	0.02233	0.2094	0.1861	CBS/LTC4S/RNASE1/SDS/THNSL2/FECH/ALOX5AP/TYW1/ECHS1/GOT1/PCBD1/CD38/ME2/CA12/IREB2/UROD/MGST3/HMGCL/RNASE2/ENO2/UROS/NPR2/ECI1/HDC/GGCX/GMDS/ADCY1/PCK2/CA2/HMGB1/SRR/GGCT/ADCY2/ALDOC/GLO1/SGPL1/FH/HMGA2	38
MF	GO:0030674	protein binding, bridging	35/2603	170/17697	0.0229	0.2104	0.187	FBXW7/SH2B2/HERPUD1/TRIM22/CRADD/ITSN2/SH2D2A/BAIAP2/NCK2/CHN1/AP2M1/MMS19/CD28/ANK3/NMD3/ARRB1/GRB10/SHB/GATAD2A/TRAT1/DET1/TP53BP2/TEX261/SORBS2/RAD50/OPTN/LAT/ERCC2/TJP2/HIP1R/SH2B3/SH3BGR/ADAP2/SH3BGRL/SORBS1	35
MF	GO:0016209	antioxidant activity	20/2603	86/17697	0.02294	0.2104	0.187	LTC4S/PTGS1/ALOX5AP/APOM/NQO1/APOE/GPX3/PRDX6/MGST3/GSTZ1/PXDN/GPX1/CAT/GPX4/IPCEF1/SOD1/HBB/PRDX2/SESN1/TXNRD2	20
MF	GO:0001158	enhancer sequence-specific DNA binding	26/2603	119/17697	0.02299	0.2104	0.187	SOX9/HIVEP1/ZNF281/REL/BACH1/HOXB6/NFKB1/RELB/HOXB5/SFPQ/RUVBL2/NFE2L1/HOXA5/HDAC1/SMARCD2/SIX3/CREB1/ATF2/XBP1/HOXA7/NR5A2/ATF4/NFYC/PBX3/HMGA1/NR1D2	26
MF	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	9/2603	30/17697	0.02464	0.2237	0.1988	DAPP1/FCHSD2/PLEKHA4/PLEKHA1/ARAP3/RS1/HIP1R/ADAP2/NCF1	9
MF	GO:0001047	core promoter binding	14/2603	55/17697	0.02533	0.2281	0.2028	STAT1/EZH2/MED1/ZNF451/KDM3A/POU2F1/MYC/MMP12/RUVBL2/HDAC1/PRDM10/BAZ2A/CEBPB/POGZ	14
MF	GO:0050750	low-density lipoprotein particle receptor binding	7/2603	21/17697	0.02598	0.2318	0.206	CLU/LRPAP1/APOE/AP2M1/DNAJA1/SNX17/SYT1	7
MF	GO:0001046	core promoter sequence-specific DNA binding	12/2603	45/17697	0.02613	0.2318	0.206	STAT1/EZH2/MED1/ZNF451/KDM3A/POU2F1/RUVBL2/HDAC1/PRDM10/BAZ2A/CEBPB/POGZ	12
MF	GO:0042379	chemokine receptor binding	16/2603	66/17697	0.02735	0.2407	0.214	CXCL9/CXCL10/STAT1/CCL5/CXCL13/CCL18/CXCL11/CXCL2/JAK1/CCL8/XCL1/CXCL3/CCL13/CCL7/CXCL8/CCR2	16
MF	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	6/2603	17/17697	0.02914	0.2487	0.2211	PTPRE/PTPRF/PTPRC/PTPRN2/PTPRK/PTPRH	6
MF	GO:0019198	transmembrane receptor protein phosphatase activity	6/2603	17/17697	0.02914	0.2487	0.2211	PTPRE/PTPRF/PTPRC/PTPRN2/PTPRK/PTPRH	6
MF	GO:0042813	Wnt-activated receptor activity	6/2603	17/17697	0.02914	0.2487	0.2211	EGF/FZD3/LRP5/FZD6/FZD7/FZD2	6
MF	GO:0055106	ubiquitin-protein transferase regulator activity	6/2603	17/17697	0.02914	0.2487	0.2211	FBXW7/TRIB1/CDC20/GLMN/RING1/FBXO5	6
MF	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	79/2603	439/17697	0.0311	0.2619	0.2328	ZIC1/PITX1/SIX1/NOTCH1/CEBPA/AR/STAT1/IRF1/HOXA10/HOXC10/SOX9/ZNF292/RFX5/ELF4/SMAD3/RORA/MYBL1/FOXC1/MEOX1/REL/NDN/BACH1/ATF3/BCL11B/CREB3/LEF1/HNRNPK/IRF3/KLF6/HOXA4/FOXF1/NFKB1/STAT4/MAFF/DMTF1/ATF6/TFEC/SIX2/TBX5/ETV6/MGA/MYC/NR1H2/EGR1/TLX2/TXK/RBPJ/HOXB5/BATF/NFE2L1/IRF2BP1/HIF1A/HOXA5/YBX1/FOXJ3/TARDBP/HLF/PRDM4/SIX6/SIX3/MAF/CEBPG/CREB1/STAT5A/HOXC11/ATF2/PATZ1/EP300/FOXJ2/HOXA7/CEBPB/NR5A2/ATF4/NFYC/PBX3/HMGA2/NRL/DDIT3/SATB2	79
MF	GO:0004032	alditol:NADP+ 1-oxidoreductase activity	5/2603	13/17697	0.03159	0.2619	0.2328	AKR1B1/AKR1B10/AKR7A2/AKR1C3/AKR1C4	5
MF	GO:0005172	vascular endothelial growth factor receptor binding	5/2603	13/17697	0.03159	0.2619	0.2328	PGF/ITGA5/CDH5/VEGFA/VEGFB	5
MF	GO:0031434	mitogen-activated protein kinase kinase binding	5/2603	13/17697	0.03159	0.2619	0.2328	MAP3K11/ARRB1/TRIB1/PIN1/RAF1	5
MF	GO:0004714	transmembrane receptor protein tyrosine kinase activity	15/2603	62/17697	0.03252	0.2658	0.2362	EFEMP1/EGFR/MERTK/NTRK2/INSR/KIT/ERBB2/TIE1/EPHB6/NTRK1/KDR/AXL/EPHA4/TYRO3/ERBB4	15
MF	GO:0030145	manganese ion binding	15/2603	62/17697	0.03252	0.2658	0.2362	MPPED2/LAP3/PEPD/PIM1/DYRK2/HMGCL/EXTL2/DCP2/B4GALT7/PCK2/GALNT3/PPM1B/WRN/ADCY2/ABO	15
MF	GO:0005158	insulin receptor binding	7/2603	22/17697	0.0334	0.271	0.2409	ENPP1/GRB10/PHIP/SNX2/IGF1/LMBRD1/SORBS1	7
MF	GO:0008017	microtubule binding	47/2603	246/17697	0.03399	0.2738	0.2434	DYSF/CETN2/CEP350/ARL3/SNCA/NDE1/MACF1/GABARAPL2/MDM1/FGF13/CCDC88C/KIF2A/PRNP/RACGAP1/MAPRE3/NUSAP1/SPAG5/ARHGEF2/MAP7D3/CRYAB/KIF18B/DRG1/PRC1/KRIT1/EML1/KIF5C/CENPE/KIF11/DYNC1I1/MAP4K4/KIF4A/CLASP1/KIF15/TUBGCP5/CCDC181/BIRC5/MTUS2/PEX14/SPAST/KATNB1/HOOK2/MAPRE2/EML4/KIF20A/VAPA/TUBGCP2/GABARAP	47
MF	GO:0016853	isomerase activity	32/2603	158/17697	0.03519	0.2815	0.2502	HPGDS/TBXAS1/ECI2/PIGK/GNPDA1/DHRS9/MPI/PGM1/PPIC/PUS7/ECH1/GSTZ1/FKBP8/NKTR/ECI1/PTGDS/TOP1/HYI/PIN1/FKBP10/TOP2A/PPIE/DCT/SPAST/SRR/ISYNA1/PUS1/ERP44/PPIB/PMM1/RPE/PPIH	32
MF	GO:0016860	intramolecular oxidoreductase activity	12/2603	47/17697	0.03597	0.2843	0.2527	HPGDS/TBXAS1/ECI2/PIGK/GNPDA1/MPI/ECH1/ECI1/PTGDS/HYI/DCT/ERP44	12
MF	GO:0050660	flavin adenine dinucleotide binding	18/2603	79/17697	0.03603	0.2843	0.2527	CYB5R1/MICAL1/IVD/ACOX2/DDO/COQ6/MICAL2/DLD/NOS3/DHCR24/FMO3/ACADM/ACOX1/AGPS/FMO4/CYB5R3/DUS4L/TXNRD2	18
MF	GO:0030414	peptidase inhibitor activity	36/2603	182/17697	0.03692	0.2853	0.2536	BIRC3/PROS1/SNCA/SLPI/SERPINA3/SPOCK1/SERPINA1/SERPINA5/PTTG1/TIMP2/SERPINE1/APLP2/BIRC2/BIRC7/ITIH4/SERPINB6/TNFAIP8/NOL3/LEF1/TFPI/ARRB1/CD27/AGT/SERPINA4/TIMP4/BIRC5/CST7/NAIP/COL6A3/SPOCK2/TNFSF14/TIMP1/CST4/RPS6KA1/SERPINF1/USP14	36
MF	GO:0061135	endopeptidase regulator activity	36/2603	182/17697	0.03692	0.2853	0.2536	BIRC3/PROS1/SNCA/SLPI/SERPINA3/SPOCK1/SERPINA1/SERPINA5/PTTG1/TIMP2/SERPINE1/APLP2/BIRC2/BIRC7/ITIH4/SERPINB6/TNFAIP8/NOL3/LEF1/TFPI/ARRB1/CD27/AGT/SERPINA4/TIMP4/BIRC5/CST7/NAIP/COL6A3/SPOCK2/TNFSF14/TIMP1/CST4/RPS6KA1/SERPINF1/USP14	36
MF	GO:0019843	rRNA binding	15/2603	63/17697	0.03708	0.2853	0.2536	CIRBP/RPL12/MRPL11/RPS11/ANG/RPS5/MRPS17/DDX21/RPL8/MRPS11/MRPL20/NGRN/MRPL18/IMP3/RPLP0	15
MF	GO:0004857	enzyme inhibitor activity	68/2603	375/17697	0.03716	0.2853	0.2536	GCHFR/PTN/NOTCH1/IQGAP2/BIRC3/PROS1/PRKAR2A/SNCA/SLPI/SERPINA3/SPOCK1/SERPINA1/ARL2/SERPINA5/CDKN2C/CDC42SE1/PTTG1/TIMP2/SERPINE1/APLP2/BIRC2/BIRC7/SET/SOCS1/ITIH4/SERPINB6/TNFAIP8/NOL3/LEF1/TFPI/FGFR1OP/ARRB1/HSPB1/PPP1R12A/CD27/APOC1/WDTC1/TRIB1/AGT/CDKN1C/SERPINA4/GLMN/TIMP4/BIRC5/CST7/NAIP/COL6A3/DNAJC3/SPOCK2/TAOK3/ATP2B4/CIB1/TNFSF14/RHOH/ENSA/LGALS3/KAT2B/TIMP1/CDKN1A/PDC/CST4/RPS6KA1/STYXL1/PINLYP/SERPINF1/OAZ3/USP14/FBXO5	68
MF	GO:0038191	neuropilin binding	6/2603	18/17697	0.03841	0.2929	0.2604	SEMA4D/SEMA4A/SEMA3A/SEMA4C/SEMA3F/SEMA3E	6
MF	GO:0001786	phosphatidylserine binding	14/2603	58/17697	0.03873	0.2934	0.2608	RASGRP1/SYT11/GSDMB/ASAP1/OSBPL8/SYT17/AXL/SCIN/HMGB1/RS1/GSDMD/SYT1/ANXA9/CPNE6	14
MF	GO:0042562	hormone binding	22/2603	102/17697	0.03918	0.2949	0.2621	AR/ALDH1A1/PTH1R/EGFR/INSR/HSD17B1/IDE/GPER1/NPR2/CHRNA3/CRHBP/TSPO/GHSR/VIPR1/HCRTR2/ALDH1A3/CALCR/CHRNB1/CCKAR/GHR/GALR3/ABHD2	22
MF	GO:0008094	DNA-dependent ATPase activity	16/2603	69/17697	0.04002	0.2992	0.2659	CHD8/DNA2/DDX11/CCNH/ATRX/PBRM1/RAD51C/TOP2A/CHD3/SMARCA5/ERCC2/BPTF/MNAT1/GTF2H3/RFC2/RAD51B	16
MF	GO:0000287	magnesium ion binding	41/2603	213/17697	0.04069	0.3023	0.2687	HPGDS/THTPA/SIK1/SRPK1/SPHK1/EYA2/IRAK3/MAP3K5/ILVBL/MTHFD2/ARL3/SNCA/SNRK/EPHX2/ATP8B1/PGM1/COMT/TDG/PINK1/DYRK2/HMGCL/ENO2/MAP3K8/PSPH/IRAK4/ATP8A1/NLK/TOP2A/PPM1B/ATP11B/WRN/SRR/ADCY2/ATP10A/WEE1/PRPS1/RPS6KA1/PRPS2/CERK/MVK/PPA2	41
MF	GO:0004177	aminopeptidase activity	12/2603	48/17697	0.04177	0.3083	0.274	TRHDE/LAP3/METAP1/PEPD/NAALAD2/LNPEP/RNPEP/TPP2/METAP2/ANPEP/DPP8/PRSS16	12
MF	GO:0016493	C-C chemokine receptor activity	7/2603	23/17697	0.0421	0.3087	0.2744	CX3CR1/CCR5/CXCR4/CCR7/CXCR2/CCR2/CXCR6	7
MF	GO:0035497	cAMP response element binding	5/2603	14/17697	0.04333	0.3099	0.2755	CREB3/ATF6/CREB1/ATF2/HMGA2	5
MF	GO:0098847	sequence-specific single stranded DNA binding	5/2603	14/17697	0.04333	0.3099	0.2755	HNRNPA2B1/RPA1/HNRNPA1/RAD50/NABP2	5
MF	GO:0001085	RNA polymerase II transcription factor binding	31/2603	155/17697	0.04381	0.3099	0.2755	PITX1/AR/ERCC1/SMAD3/GSK3B/BEX1/TCERG1/PPARG/BBS1/BBS4/ID4/ZFPM2/GTF2A2/CTDP1/TBX5/MGA/RBPJ/TAF7/MTDH/RUVBL2/NCOR1/HDAC1/SPEN/CREB1/ID2/ID3/TCF7L2/ATF2/EP300/ATF4/RBL2	31
MF	GO:0005227	calcium activated cation channel activity	8/2603	28/17697	0.04382	0.3099	0.2755	KCNN3/MTMR6/PKD2L1/ANO1/KCNN2/ANO10/CCT8L2/KCNMB2	8
MF	GO:0004536	deoxyribonuclease activity	14/2603	59/17697	0.04415	0.3099	0.2755	DNASE1L3/DCLRE1C/ERCC1/DNASE1L1/DNA2/ISG20/SETMAR/TATDN2/DNASE2/RAD51C/RAD50/RAD1/DFFB/RAD9A	14
MF	GO:0035258	steroid hormone receptor binding	20/2603	92/17697	0.04427	0.3099	0.2755	SMAD3/PRKCB/NCOA3/NCOA6/MMS19/LEF1/MED1/PPARG/KDM3A/ARRB1/YWHAH/TAF10/DAXX/KAT5/PADI2/RNF14/FHL2/EP300/ETS2/CEBPB	20
MF	GO:0005154	epidermal growth factor receptor binding	9/2603	33/17697	0.04427	0.3099	0.2755	EFEMP1/BTC/EGF/ITGA5/SNX2/HBEGF/EREG/ERBB4/MS4A1	9
MF	GO:0042626	ATPase activity, coupled to transmembrane movement of substances	24/2603	115/17697	0.04568	0.3099	0.2755	TAP1/ATP1B1/CD320/ATP2A3/ATP6V0D1/ABCC10/ABCC4/ABCA8/ATP2C1/ABCA3/TAPBP/TCIRG1/ATP2B2/ABCC1/ABCA2/ATP8A1/TAP2/ATP6V0E2/ABCC8/ABCA11P/ABCB1/ATP2B4/LMBRD1/ATP2B1	24
MF	GO:0043492	ATPase activity, coupled to movement of substances	24/2603	115/17697	0.04568	0.3099	0.2755	TAP1/ATP1B1/CD320/ATP2A3/ATP6V0D1/ABCC10/ABCC4/ABCA8/ATP2C1/ABCA3/TAPBP/TCIRG1/ATP2B2/ABCC1/ABCA2/ATP8A1/TAP2/ATP6V0E2/ABCC8/ABCA11P/ABCB1/ATP2B4/LMBRD1/ATP2B1	24
MF	GO:0000014	single-stranded DNA endodeoxyribonuclease activity	4/2603	10/17697	0.04687	0.3099	0.2755	DCLRE1C/ERCC1/SETMAR/RAD50	4
MF	GO:0004690	cyclic nucleotide-dependent protein kinase activity	4/2603	10/17697	0.04687	0.3099	0.2755	PRKX/PRKAG1/PRKAA1/AKAP13	4
MF	GO:0004691	cAMP-dependent protein kinase activity	4/2603	10/17697	0.04687	0.3099	0.2755	PRKX/PRKAG1/PRKAA1/AKAP13	4
MF	GO:0004955	prostaglandin receptor activity	4/2603	10/17697	0.04687	0.3099	0.2755	HPGD/PPARG/PTGER4/PTGFR	4
MF	GO:0016803	ether hydrolase activity	4/2603	10/17697	0.04687	0.3099	0.2755	EPHX1/EPHX2/AKR7A2/RNPEP	4
MF	GO:0030957	Tat protein binding	4/2603	10/17697	0.04687	0.3099	0.2755	GABARAPL1/DNAJA1/CTDP1/TRIM32	4
MF	GO:0070016	armadillo repeat domain binding	4/2603	10/17697	0.04687	0.3099	0.2755	CHD8/CTNNBIP1/LEF1/TCF7L2	4
MF	GO:0098505	G-rich strand telomeric DNA binding	4/2603	10/17697	0.04687	0.3099	0.2755	HNRNPA2B1/RPA1/HNRNPA1/NABP2	4
MF	GO:0017046	peptide hormone binding	12/2603	49/17697	0.04818	0.3168	0.2816	PTH1R/INSR/IDE/NPR2/CRHBP/GHSR/VIPR1/HCRTR2/CALCR/CCKAR/GHR/GALR3	12
MF	GO:1902936	phosphatidylinositol bisphosphate binding	23/2603	110/17697	0.0487	0.3172	0.282	DAPP1/KCNQ1/GSDMB/FCHSD2/PFN2/ASAP1/PLEKHA4/PLEKHA1/KCNJ2/KRIT1/ARAP3/ACAP2/SCIN/RS1/PLCD1/TPCN1/GSDMD/HIP1R/SYT1/FZD7/EXOC1/ADAP2/NCF1	23
MF	GO:0051015	actin filament binding	38/2603	198/17697	0.04915	0.3172	0.282	MICAL1/IQGAP2/ACTR3B/LCP1/ARPC1A/MACF1/CLMN/MICALL2/TMOD1/SYNE2/EGFR/ACTR3/CORO2B/PSTPIP2/MYOM2/CAPZA1/BIN1/NEBL/FERMT2/MYO16/VPS16/WIPF1/PKNOX2/SCIN/FERMT1/MYL4/CACNB2/ARPC5L/MYH4/TLN2/CTTN/HIP1R/CYFIP1/LIMA1/ACTN1/FLNA/ACTR2/MYH10	38
MF	GO:0004550	nucleoside diphosphate kinase activity	6/2603	19/17697	0.04936	0.3172	0.282	NME4/NME7/NME5/NME3/AK1/SUCLG1	6
MF	GO:0016505	peptidase activator activity involved in apoptotic process	6/2603	19/17697	0.04936	0.3172	0.282	BAD/NLRP1/CARD8/APAF1/CASP8AP2/NOD1	6
MF	GO:0070491	repressing transcription factor binding	16/2603	71/17697	0.05051	0.3228	0.2869	STAT1/SRI/TCERG1/PPARG/BBS1/BBS4/GTF2A2/MYC/RBPJ/HMGB1/KAT5/TLE3/HDAC1/TCF3/TCF7L2/TLE2	16
MF	GO:0008083	growth factor activity	32/2603	163/17697	0.05127	0.3254	0.2892	EFEMP1/PTN/CD320/PGF/THBS4/BTC/HGF/FGF14/FGF13/EGF/NTF3/BMP4/GDF5/FGF20/TYMP/RABEP2/AGT/IGF1/FGF18/IL6/HBEGF/EREG/PDGFB/VEGFA/JAG2/GDF9/IL6R/TIMP1/INHBB/FGF5/BDNF/VEGFB	32
MF	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	10/2603	39/17697	0.05155	0.3254	0.2892	MICAL1/CH25H/COQ6/MICAL2/NOS3/AKR1C3/FMO3/CYP4F11/FMO4/AKR1C4	10
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	26/2603	128/17697	0.05177	0.3254	0.2892	AKR1B1/VKORC1/CRYL1/AKR1B10/AKR7A3/DHRS3/DHRS9/ME2/IMPDH2/HSD11B2/HSD17B10/ABCC4/BDH2/HSD17B1/SORD/HPGD/AKR7A2/HADH/MDH2/GRHPR/AKR1C3/ALDH3A2/HSD17B14/CBR1/MDH1/AKR1C4	26
MF	GO:0019957	C-C chemokine binding	7/2603	24/17697	0.05214	0.3254	0.2892	CX3CR1/CCR5/CXCR4/CCR7/CXCR2/CCR2/CXCR6	7
MF	GO:0070851	growth factor receptor binding	27/2603	134/17697	0.05254	0.3254	0.2892	EFEMP1/JAK2/PGF/TRIP6/BTC/ADAM17/EGF/ITGA5/FGF20/TOLLIP/CDH5/SNX2/FGF18/IL6/HBEGF/TLR5/IRAK4/EREG/PDGFB/VEGFA/GLMN/IL1RN/IL6R/ERBB4/MS4A1/FGF5/VEGFB	27
MF	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	9/2603	34/17697	0.05264	0.3254	0.2892	GCH1/MTHFD2/ADAR/ADA/APOBEC3C/APOBEC3B/DCTD/ADARB2/AMPD3	9
MF	GO:0051059	NF-kappaB binding	8/2603	29/17697	0.05298	0.3254	0.2892	NFKBIA/GSK3B/TP53BP2/MTDH/AKAP8/HDAC1/BCL10/EP300	8
MF	GO:0042826	histone deacetylase binding	23/2603	111/17697	0.0532	0.3254	0.2892	BEX4/HOXA10/NIPBL/KPNA2/LEF1/ZNHIT1/PHB/WDTC1/INSM1/CDC20/PRDM1/TOP2A/SFPQ/NCOR1/HIF1A/AKAP8/HDAC1/SIX3/RAD9A/KAT2B/CRY1/HNRNPD/CEBPB	23
MF	GO:0002039	p53 binding	15/2603	66/17697	0.05347	0.3254	0.2892	RNF125/CHD8/RFWD3/GSK3B/PRMT5/PPP1R13B/SMYD2/DAXX/TP53BP2/TRIM24/HIF1A/HDAC1/BANP/EP300/RNF34	15
MF	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	25/2603	123/17697	0.05527	0.3319	0.295	GCH1/MTHFD2/ADAR/DDAH1/ADA/AGMAT/APOBEC3C/NAALAD2/DPYS/ASRGL1/ASAH1/CAT/DDAH2/SIRT3/NGLY1/APOBEC3B/DCTD/NADSYN1/ADARB2/HDAC1/PADI2/VNN1/SAP30/AMPD3/SIRT7	25
MF	GO:0051219	phosphoprotein binding	18/2603	83/17697	0.0554	0.3319	0.295	FBXW7/MAPK3/PLCG2/TBK1/SNCA/TOX3/NCK2/DPYS/RRAGA/FGR/ARRB1/ZAP70/CBLB/LCK/SHB/TBL2/PIN1/SCAF4	18
MF	GO:0004725	protein tyrosine phosphatase activity	21/2603	100/17697	0.05541	0.3319	0.295	PTPRE/CDC25B/DUSP5/EYA2/DUSP6/MTMR4/PTPRF/PTPRC/PTPN7/RNGTT/MTMR6/PTPN22/CDC14A/PTPN2/SSH3/PTPRN2/MTMR1/DUSP2/PTPRK/ACP1/PTPRH	21
MF	GO:0001056	RNA polymerase III activity	5/2603	15/17697	0.05736	0.34	0.3022	POLR2L/POLR3C/POLR2E/POLR2F/POLR1C	5
MF	GO:1901611	phosphatidylglycerol binding	5/2603	15/17697	0.05736	0.34	0.3022	NME4/ATP8B1/PITPNC1/GSDMD/STOML2	5
MF	GO:0001540	amyloid-beta binding	17/2603	78/17697	0.05898	0.3468	0.3083	TREM2/CLU/LILRB2/LRPAP1/PRNP/APOE/INSR/IDE/GSAP/PGRMC1/GRIA2/CRYAB/ADRB2/ITM2C/EPHA4/CALCR/NGFR	17
MF	GO:0005496	steroid binding	20/2603	95/17697	0.05914	0.3468	0.3083	AR/OSBPL3/RORA/ERLIN2/GPR183/HSD11B2/GRAMD1C/APOE/HSD17B1/OSBPL8/PGRMC1/GPER1/CD81/TSPO/SCP2/NR3C2/IRX5/PGRMC2/NFE2L1/NPC1	20
MF	GO:0003707	steroid hormone receptor activity	13/2603	56/17697	0.05972	0.3468	0.3083	AR/RORA/RXRA/LEF1/PPARG/GPER1/NR1H2/NR3C2/NR2F1/PGRMC2/ABHD2/NR5A2/NR1D2	13
MF	GO:0043621	protein self-association	13/2603	56/17697	0.05972	0.3468	0.3083	TNFAIP3/CCL5/MALT1/PTH1R/CCDC88C/TDG/PPARG/MDH2/VAMP2/CD2/BCL10/TRIM32/MYD88	13
MF	GO:0005355	glucose transmembrane transporter activity	6/2603	20/17697	0.06204	0.3531	0.3139	SLC2A3/SLC2A6/SLC5A3/SLC2A11/SLC2A9/SLC2A5	6
MF	GO:0015149	hexose transmembrane transporter activity	6/2603	20/17697	0.06204	0.3531	0.3139	SLC2A3/SLC2A6/SLC5A3/SLC2A11/SLC2A9/SLC2A5	6
MF	GO:0042288	MHC class I protein binding	6/2603	20/17697	0.06204	0.3531	0.3139	TAP1/LILRB2/CD8A/HLA-E/TAPBP/TAP2	6
MF	GO:0061608	nuclear import signal receptor activity	6/2603	20/17697	0.06204	0.3531	0.3139	KPNA2/SNUPN/TNPO1/KPNB1/KPNA1/KPNA3	6
MF	GO:0045309	protein phosphorylated amino acid binding	12/2603	51/17697	0.06295	0.3557	0.3162	FBXW7/MAPK3/PLCG2/NCK2/FGR/ARRB1/ZAP70/CBLB/LCK/SHB/PIN1/SCAF4	12
MF	GO:0008235	metalloexopeptidase activity	14/2603	62/17697	0.06356	0.3557	0.3162	TRHDE/CPA3/LAP3/METAP1/PEPD/AGTPBP1/CPD/CPQ/LNPEP/CPE/AGBL5/RNPEP/METAP2/ANPEP	14
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	24/2603	119/17697	0.06404	0.3557	0.3162	AKR1B1/CRYL1/AKR1B10/AKR7A3/DHRS3/DHRS9/ME2/IMPDH2/HSD11B2/HSD17B10/ABCC4/BDH2/HSD17B1/SORD/HPGD/AKR7A2/HADH/MDH2/GRHPR/AKR1C3/HSD17B14/CBR1/MDH1/AKR1C4	24
MF	GO:0004954	prostanoid receptor activity	4/2603	11/17697	0.0653	0.3557	0.3162	HPGD/PPARG/PTGER4/PTGFR	4
MF	GO:0005035	death receptor activity	4/2603	11/17697	0.0653	0.3557	0.3162	TNFRSF1B/TNFRSF11A/TNFRSF14/NGFR	4
MF	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	4/2603	11/17697	0.0653	0.3557	0.3162	DDAH1/AGMAT/DDAH2/PADI2	4
MF	GO:0043560	insulin receptor substrate binding	4/2603	11/17697	0.0653	0.3557	0.3162	JAK2/INSR/PIK3CB/PIK3CA	4
MF	GO:0052650	NADP-retinol dehydrogenase activity	4/2603	11/17697	0.0653	0.3557	0.3162	AKR1B1/AKR1B10/DHRS3/AKR1C3	4
MF	GO:1901612	cardiolipin binding	4/2603	11/17697	0.0653	0.3557	0.3162	NME4/ATP8B1/GSDMD/STOML2	4
MF	GO:0042805	actinin binding	11/2603	46/17697	0.06619	0.3589	0.319	MICALL2/PDLIM1/MYOM2/PDLIM4/PDLIM2/PPARG/NFKB1/PKD2L1/ALMS1/KCNN2/CACNA1D	11
MF	GO:0003899	DNA-directed 5'-3' RNA polymerase activity	10/2603	41/17697	0.06935	0.3725	0.3311	POLR2J/POLR2I/POLR2L/POLR3C/POLR2E/POLR2F/POLR2C/POLR1B/POLR2G/POLR1C	10
MF	GO:0004520	endodeoxyribonuclease activity	10/2603	41/17697	0.06935	0.3725	0.3311	DNASE1L3/DCLRE1C/ERCC1/DNASE1L1/DNA2/SETMAR/TATDN2/DNASE2/RAD51C/RAD50	10
MF	GO:0017080	sodium channel regulator activity	9/2603	36/17697	0.07229	0.3814	0.339	SCN1B/SNTA1/FXYD1/FXYD6/FGF13/YWHAH/RANGRF/ATP2B4/NEDD4L	9
MF	GO:0043394	proteoglycan binding	9/2603	36/17697	0.07229	0.3814	0.339	PTN/PLA2G2D/PTPRF/PTPRC/APOE/FGF20/COMP/COL5A3/LPL	9
MF	GO:0047485	protein N-terminus binding	22/2603	109/17697	0.07323	0.3814	0.339	SNCA/ALOX5AP/NBN/NIPBL/PEX19/NCOA3/ATM/BIRC2/CHMP6/BANF1/DAXX/EXOC2/RND2/RBPJ/PEX14/ACOX1/ERCC2/HDAC1/NPAT/MNAT1/GTF2H3/MORF4L1	22
MF	GO:0000400	four-way junction DNA binding	5/2603	16/17697	0.07368	0.3814	0.339	HMGB3/HMGB1/RAD51C/WRN/RAD51B	5
MF	GO:0005149	interleukin-1 receptor binding	5/2603	16/17697	0.07368	0.3814	0.339	TRIP6/TOLLIP/TLR5/IRAK4/IL1RN	5
MF	GO:0005159	insulin-like growth factor receptor binding	5/2603	16/17697	0.07368	0.3814	0.339	INSR/SOCS1/ARRB1/YWHAH/IGF1	5
MF	GO:0005521	lamin binding	5/2603	16/17697	0.07368	0.3814	0.339	LBR/PRNP/NARF/TOR1AIP1/TMPO	5
MF	GO:0008191	metalloendopeptidase inhibitor activity	5/2603	16/17697	0.07368	0.3814	0.339	SPOCK1/TIMP2/TIMP4/SPOCK2/TIMP1	5
MF	GO:0001637	G protein-coupled chemoattractant receptor activity	7/2603	26/17697	0.07639	0.3837	0.341	CX3CR1/CCR5/CXCR4/CCR7/CXCR2/CCR2/CXCR6	7
MF	GO:0004033	aldo-keto reductase (NADP) activity	7/2603	26/17697	0.07639	0.3837	0.341	AKR1B1/AKR1B10/AKR7A3/DHRS3/AKR7A2/AKR1C3/AKR1C4	7
MF	GO:0004950	chemokine receptor activity	7/2603	26/17697	0.07639	0.3837	0.341	CX3CR1/CCR5/CXCR4/CCR7/CXCR2/CCR2/CXCR6	7
MF	GO:0051787	misfolded protein binding	7/2603	26/17697	0.07639	0.3837	0.341	CLU/CLUL1/HSPA6/EDEM1/DNAJC3/HSPA2/HSPA5	7
MF	GO:0070325	lipoprotein particle receptor binding	7/2603	26/17697	0.07639	0.3837	0.341	CLU/LRPAP1/APOE/AP2M1/DNAJA1/SNX17/SYT1	7
MF	GO:0008106	alcohol dehydrogenase (NADP+) activity	6/2603	21/17697	0.07647	0.3837	0.341	AKR1B1/AKR1B10/DHRS3/AKR7A2/AKR1C3/AKR1C4	6
MF	GO:0016018	cyclosporin A binding	6/2603	21/17697	0.07647	0.3837	0.341	PPIC/NKTR/PPP3CA/PPIE/PPIB/PPIH	6
MF	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	16/2603	75/17697	0.07695	0.3844	0.3417	KCNQ1/GSDMB/PFN2/ASAP1/PLEKHA4/KCNJ2/KRIT1/SCIN/RS1/PLCD1/GSDMD/HIP1R/SYT1/FZD7/EXOC1/ADAP2	16
MF	GO:0004402	histone acetyltransferase activity	14/2603	64/17697	0.07925	0.3913	0.3478	NCOA3/TADA3/TAF10/BRPF1/NAA50/ELP3/BRCA2/TAF9B/KAT6A/KAT5/OGT/KAT2B/ATF2/EP300	14
MF	GO:0033293	monocarboxylic acid binding	14/2603	64/17697	0.07925	0.3913	0.3478	ALOX5AP/ACOX2/SERPINA5/RXRA/PPARG/PC/APOC1/SCP2/PTGDS/CYP4F11/ACOX1/ID3/FABP3/PSAP	14
MF	GO:0016407	acetyltransferase activity	22/2603	110/17697	0.07936	0.3913	0.3478	SPHK1/NCOA3/TADA3/GCAT/TAF10/NAA16/BRPF1/ACAT1/NAA50/ELP3/BRCA2/TAF9B/KAT6A/KAT5/NAT2/OGT/ACAA2/LPCAT4/KAT2B/ATF2/CRAT/EP300	22
MF	GO:0004721	phosphoprotein phosphatase activity	34/2603	182/17697	0.08151	0.4002	0.3557	PTPRE/CDC25B/DUSP5/EYA2/PPP1R3C/DUSP6/MTMR4/PTPRF/PTPRC/DLGAP5/PTPN7/CTDSPL/RNGTT/MTMR6/PTPN22/SHOC2/PPP4R1/CDC14A/PTPN2/SSH3/LCK/PPM1E/PTPRN2/CTDP1/MTMR1/DUSP2/PPP3CA/PPM1B/PTPRK/ACP1/PTPRH/PHLPP1/STYXL1/PPA2	34
MF	GO:0051393	alpha-actinin binding	9/2603	37/17697	0.08361	0.4087	0.3633	PDLIM1/MYOM2/PDLIM4/PDLIM2/PPARG/PKD2L1/ALMS1/KCNN2/CACNA1D	9
MF	GO:0016597	amino acid binding	13/2603	59/17697	0.08456	0.4098	0.3642	GCHFR/THNSL2/DDAH1/UBR2/DPYS/DDAH2/ASS1/NOS3/CPS1/SRR/SESN1/SLC1A1/TH	13
MF	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	4/2603	12/17697	0.08692	0.4098	0.3642	CDKN2C/CDKN1C/KAT2B/CDKN1A	4
MF	GO:0019992	diacylglycerol binding	4/2603	12/17697	0.08692	0.4098	0.3642	RASGRP1/RASGRP3/RASGRP2/CHPT1	4
MF	GO:0031994	insulin-like growth factor I binding	4/2603	12/17697	0.08692	0.4098	0.3642	IGFBP5/IGFBP2/INSR/IGFBP4	4
MF	GO:0032036	myosin heavy chain binding	4/2603	12/17697	0.08692	0.4098	0.3642	LIMCH1/MYL3/AXL/MYL4	4
MF	GO:0042975	peroxisome proliferator activated receptor binding	4/2603	12/17697	0.08692	0.4098	0.3642	MED1/ASXL2/IKBKG/HMGA1	4
MF	GO:0045295	gamma-catenin binding	4/2603	12/17697	0.08692	0.4098	0.3642	CDH2/LEF1/PTPRK/TCF7L2	4
MF	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity	24/2603	123/17697	0.08701	0.4098	0.3642	TAP1/ATP1B1/CD320/ATP2A3/ATP6V0D1/ABCC10/ABCC4/ABCA8/ATP2C1/ABCA3/TAPBP/TCIRG1/ATP2B2/ABCC1/ABCA2/ATP8A1/TAP2/ATP6V0E2/ABCC8/ABCA11P/ABCB1/ATP2B4/LMBRD1/ATP2B1	24
MF	GO:0019239	deaminase activity	8/2603	32/17697	0.0874	0.4098	0.3642	ADAR/GNPDA1/ADA/APOBEC3C/APOBEC3B/DCTD/ADARB2/AMPD3	8
MF	GO:0019956	chemokine binding	8/2603	32/17697	0.0874	0.4098	0.3642	CX3CR1/CCR5/CXCR4/HMGB1/CCR7/CXCR2/CCR2/CXCR6	8
MF	GO:0045499	chemorepellent activity	7/2603	27/17697	0.09061	0.4139	0.3679	SEMA4D/SEMA4A/SEMA3A/SEMA4C/EFNA5/SEMA3F/SEMA3E	7
MF	GO:0048020	CCR chemokine receptor binding	10/2603	43/17697	0.09062	0.4139	0.3679	STAT1/CCL5/CXCL13/CCL18/JAK1/CCL8/XCL1/CCL13/CCL7/CCR2	10
MF	GO:0017022	myosin binding	15/2603	71/17697	0.09076	0.4139	0.3679	RAB27A/LIMCH1/RALA/TRAK1/MYL3/CXCR4/SPATA6/MYOC/AXL/LLGL2/MYL4/RAB11B/LARP6/TRIM32/ARFGEF1	15
MF	GO:0008234	cysteine-type peptidase activity	34/2603	184/17697	0.09177	0.4139	0.3679	TNFAIP3/SFRP1/LGMN/USP11/UFSP2/CTSW/USP46/MALT1/PIGK/UCHL1/CFLAR/USP3/USP24/CASP4/CTSF/CAPNS1/USPL1/CTSO/USP47/SENP5/USP32/USP34/USP27X/ANKZF1/CASP9/USP8/UCHL3/USP9X/USP12/CYLD/ATG4A/USP48/USP21/USP14	34
MF	GO:0005123	death receptor binding	5/2603	17/17697	0.09224	0.4139	0.3679	CFLAR/MADD/NOL3/CASP8AP2/MYD88	5
MF	GO:0030275	LRR domain binding	5/2603	17/17697	0.09224	0.4139	0.3679	POLR2J/KRAS/ATF4/NRL/DDIT3	5
MF	GO:0035014	phosphatidylinositol 3-kinase regulator activity	5/2603	17/17697	0.09224	0.4139	0.3679	SOCS6/SOCS1/PIK3R5/WDR91/CISH	5
MF	GO:0042834	peptidoglycan binding	5/2603	17/17697	0.09224	0.4139	0.3679	TREM2/IGHM/NOD2/NOD1/REG3A	5
MF	GO:0050811	GABA receptor binding	5/2603	17/17697	0.09224	0.4139	0.3679	GABARAPL1/GABARAPL2/GABRB1/TRAK1/GABARAP	5
MF	GO:0003950	NAD+ ADP-ribosyltransferase activity	6/2603	22/17697	0.09262	0.4139	0.3679	PARP12/PARP3/TNKS2/PARP6/PARP8/PARP4	6
MF	GO:0015145	monosaccharide transmembrane transporter activity	6/2603	22/17697	0.09262	0.4139	0.3679	SLC2A3/SLC2A6/SLC5A3/SLC2A11/SLC2A9/SLC2A5	6
MF	GO:0050145	nucleoside monophosphate kinase activity	6/2603	22/17697	0.09262	0.4139	0.3679	AK1/AK6/GUK1/RAD50/MPP1/TJP2	6
MF	GO:0044325	ion channel binding	24/2603	124/17697	0.09351	0.4162	0.37	SCN1B/SNTA1/FXYD1/SRI/RIMS3/KCNQ1/HERPUD1/SH3GL1/FGF13/PRNP/AP2M1/ANK3/ARRB1/YWHAH/CDH5/TSPO/ABCC8/AKAP9/RANGRF/CIB1/ID2/ACTN1/FLNA/NEDD4L	24
MF	GO:0061733	peptide-lysine-N-acetyltransferase activity	14/2603	66/17697	0.09724	0.4312	0.3833	NCOA3/TADA3/TAF10/BRPF1/NAA50/ELP3/BRCA2/TAF9B/KAT6A/KAT5/OGT/KAT2B/ATF2/EP300	14
MF	GO:0003727	single-stranded RNA binding	19/2603	95/17697	0.09762	0.4312	0.3833	CIRBP/DDX11/JMJD6/PABPC3/TIA1/LARP4/POLR2G/HNRNPA1/L1TD1/PPIE/ZFR2/DDX1/ADARB2/AGO3/DDX60/TARDBP/PUS1/DAZAP1/TLR8	19
MF	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	29/2603	155/17697	0.09964	0.438	0.3893	SUZ12/GAMT/PEMT/DNMT1/EZH2/COMT/METTL8/TARBP1/METTL22/PRMT5/CMTR1/SETD5/LCMT1/SETMAR/TRMT112/SMYD2/SETD1B/METTL4/VCPKMT/EED/DIMT1/SETD2/SUV39H2/HNMT/CXXC1/TFB2M/TRMT5/MEPCE/NSUN6	29
MF	GO:0015399	primary active transmembrane transporter activity	24/2603	125/17697	0.1003	0.438	0.3893	TAP1/ATP1B1/CD320/ATP2A3/ATP6V0D1/ABCC10/ABCC4/ABCA8/ATP2C1/ABCA3/TAPBP/TCIRG1/ATP2B2/ABCC1/ABCA2/ATP8A1/TAP2/ATP6V0E2/ABCC8/ABCA11P/ABCB1/ATP2B4/LMBRD1/ATP2B1	24
MF	GO:0005319	lipid transporter activity	25/2603	131/17697	0.1004	0.438	0.3893	APOL3/OSBPL3/APOM/ATP8B1/SLC27A6/RBP4/ABCA8/GRAMD1C/APOE/ABCA3/SLC27A5/PITPNC1/OSBPL8/TMEM30A/PCTP/ABCC1/PLSCR4/ABCA2/GM2A/ABCA11P/ABCB1/FABP3/AKR1C4/NPC1/STARD7	25
MF	GO:0008375	acetylglucosaminyltransferase activity	12/2603	55/17697	0.1007	0.438	0.3893	MGAT4C/EOGT/EXT2/PIGA/PIGP/RFNG/GCNT3/HEXA/EXTL2/PIGH/OGT/PIGC	12
MF	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism	8/2603	33/17697	0.1012	0.4386	0.3898	ATP1B1/ATP2A3/ATP6V0D1/ABCC4/ATP2C1/ATP2B2/ATP2B4/ATP2B1	8
MF	GO:0018024	histone-lysine N-methyltransferase activity	10/2603	44/17697	0.1026	0.4398	0.3909	SUZ12/EZH2/SETD5/SETMAR/SMYD2/SETD1B/EED/SETD2/SUV39H2/CXXC1	10
MF	GO:0042578	phosphoric ester hydrolase activity	63/2603	367/17697	0.1039	0.4398	0.3909	PTPRE/CDC25B/DUSP5/HDDC2/EYA2/MPPED2/PPP1R3C/CCL5/ENPP1/PLCG2/PRKAR2A/DUSP6/EPHX2/MTMR4/PTPRF/PTPRC/PDE1A/G6PC3/NT5C2/DLGAP5/SYNJ1/PIKFYVE/PTPN7/CTDSPL/CCR5/RNGTT/SAMHD1/MTMR6/PLD3/GDPD5/PTPN22/SHOC2/PLD1/PPP4R1/CDC14A/PFKFB3/PTPN2/SSH3/GDE1/LCK/PPM1E/PTPRN2/CTDP1/PSPH/MTMR1/DUSP2/PLCE1/TDP1/ACP6/PPP3CA/PPM1B/PTPRK/PLCD1/ACP1/PLCXD1/NT5E/INPP5E/PTPRH/PHLPP1/STYXL1/LPIN1/GDPD2/PPA2	63
MF	GO:0003785	actin monomer binding	7/2603	28/17697	0.1062	0.4398	0.3909	PFN2/MYL3/NOS3/PKNOX2/MYL4/TMSB10/LIMA1	7
MF	GO:0004129	cytochrome-c oxidase activity	7/2603	28/17697	0.1062	0.4398	0.3909	COX7A1/NDUFA4L2/NDUFA4/COX6C/COX8A/COX6A1/COX5B	7
MF	GO:0015002	heme-copper terminal oxidase activity	7/2603	28/17697	0.1062	0.4398	0.3909	COX7A1/NDUFA4L2/NDUFA4/COX6C/COX8A/COX6A1/COX5B	7
MF	GO:0016676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	7/2603	28/17697	0.1062	0.4398	0.3909	COX7A1/NDUFA4L2/NDUFA4/COX6C/COX8A/COX6A1/COX5B	7
MF	GO:0017056	structural constituent of nuclear pore	7/2603	28/17697	0.1062	0.4398	0.3909	NUP160/NUP153/NPAP1/TPR/NDC1/NUP98/NUP62	7
MF	GO:1901567	fatty acid derivative binding	7/2603	28/17697	0.1062	0.4398	0.3909	ECI2/ALOX5AP/HMGCL/PPARG/SCP2/ALDH6A1/ACBD3	7
MF	GO:0003779	actin binding	73/2603	431/17697	0.1064	0.4398	0.3909	GBP1/MICAL1/IQGAP2/ACTR3B/LCP1/SNTA1/ARPC1A/KLHL2/SNCA/MACF1/CLMN/EPB41L1/MICALL2/TMOD1/SYNE2/EGFR/PFN2/PDLIM1/MARCKSL1/ACTR3/CORO2B/LIMCH1/PSTPIP2/MYOM2/CAPZA1/BIN1/CCR5/PDLIM4/PDLIM2/MYL3/KLHL3/NEBL/CXCR4/SSH3/FERMT2/MICAL2/MYO16/YWHAH/VPS16/DIAPH2/WIPF1/NOS3/ANG/TMOD2/FHOD3/PKNOX2/MSRB2/SCIN/TNS1/NOD2/FERMT1/MYL4/TMSB10/CACNB2/PHACTR4/ARPC5L/NF2/MYH4/PARVB/TLN2/CTTN/HIP1R/EPS8L2/CYFIP1/LIMA1/SNTB1/ACTN1/FLNA/SYN1/CAMK2B/ACTR2/MYH10/SORBS1	73
MF	GO:0004620	phospholipase activity	20/2603	102/17697	0.1064	0.4398	0.3909	PNPLA6/CCL5/LIPC/PLCG2/ABHD6/PLA2G2D/PLA2G15/PRDX6/CCR5/PLD3/PLA2G7/GDPD5/PLD1/GDE1/PLA2G4C/PLA1A/PLCE1/PLCD1/LPL/PLBD1	20
MF	GO:0030374	nuclear receptor transcription coactivator activity	14/2603	67/17697	0.1071	0.4398	0.3909	PRKCB/MED13/NCOA3/NCOA6/TADA3/MED1/PPARG/DCAF6/NR1H2/BUD31/ACTN1/PPRC1/HMGA1/NR1D2	14
MF	GO:0051018	protein kinase A binding	11/2603	50/17697	0.1078	0.4398	0.3909	SOX9/PRKAR2A/KCNQ1/CRYBG3/GSK3B/AKAP17A/AKAP8/AKAP9/AKAP13/ARFGEF1/ACBD3	11
MF	GO:0016757	transferase activity, transferring glycosyl groups	49/2603	280/17697	0.1084	0.4398	0.3909	MGAT4C/PARP12/PARP3/GALNT11/GALNT10/SDF2/GLT8D2/EOGT/TNKS2/B4GALT2/EXT2/PIGA/PIGP/B3GALNT1/FUT1/DPM3/RFNG/TYMP/PARP6/UGCG/GCNT3/DPY19L2P2/PYGM/PNP/DPAGT1/HEXA/PARP8/ST3GAL2/POFUT1/EXTL2/UGT2B17/DAD1/B4GALT7/NAMPT/GALNT3/PARP4/PIGH/FUT8/DDOST/ALG6/OGT/HAS2/PIGZ/PIGC/ABO/ST8SIA2/FUT4/C1GALT1C1/B4GALT3	49
MF	GO:0001223	transcription coactivator binding	6/2603	23/17697	0.1104	0.4398	0.3909	SIX1/RORA/FOXC1/CCNT2/CREB1/CDK9	6
MF	GO:0030159	receptor signaling complex scaffold activity	6/2603	23/17697	0.1104	0.4398	0.3909	NCK2/MMS19/MAGI2/CD3E/CD3G/NUP62	6
MF	GO:0030215	semaphorin receptor binding	6/2603	23/17697	0.1104	0.4398	0.3909	SEMA4D/SEMA4A/SEMA3A/SEMA4C/SEMA3F/SEMA3E	6
MF	GO:0140103	catalytic activity, acting on a glycoprotein	6/2603	23/17697	0.1104	0.4398	0.3909	MGAT4C/GCNT3/B4GALT7/FUT8/ABO/C1GALT1C1	6
MF	GO:0019199	transmembrane receptor protein kinase activity	16/2603	79/17697	0.1111	0.4398	0.3909	EFEMP1/EGFR/MERTK/NTRK2/INSR/KIT/ERBB2/TIE1/EPHB6/NTRK1/KDR/AXL/EPHA4/LTBP4/TYRO3/ERBB4	16
MF	GO:0008417	fucosyltransferase activity	4/2603	13/17697	0.1115	0.4398	0.3909	FUT1/POFUT1/FUT8/FUT4	4
MF	GO:0016208	AMP binding	4/2603	13/17697	0.1115	0.4398	0.3909	MPPED2/PRKAG1/PFKM/CYB5R3	4
MF	GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	4/2603	13/17697	0.1115	0.4398	0.3909	CYB5R1/NQO1/NOS3/CYB5R3	4
MF	GO:0034236	protein kinase A catalytic subunit binding	4/2603	13/17697	0.1115	0.4398	0.3909	SOX9/PRKAR2A/KCNQ1/GSK3B	4
MF	GO:0039706	co-receptor binding	4/2603	13/17697	0.1115	0.4398	0.3909	NEO1/HFE/BMP4/DKK4	4
MF	GO:0043023	ribosomal large subunit binding	4/2603	13/17697	0.1115	0.4398	0.3909	LTN1/NMD3/EIF6/NEMF	4
MF	GO:0045159	myosin II binding	4/2603	13/17697	0.1115	0.4398	0.3909	LIMCH1/MYL3/LLGL2/MYL4	4
MF	GO:0060090	molecular adaptor activity	42/2603	237/17697	0.1118	0.4398	0.3909	WWC3/FBXW7/SH2B2/HERPUD1/TRIM22/CRADD/PDE4DIP/ITSN2/SH2D2A/BAIAP2/NCK2/CHN1/AP2M1/MMS19/CD28/ANK3/NMD3/ARRB1/GRB10/SHB/GATAD2A/TRAT1/DET1/TP53BP2/TEX261/SORBS2/RAD50/LAMTOR2/OPTN/LAT/AIMP2/ERCC2/AKAP9/AKAP13/TJP2/SLC9A3R2/HIP1R/SH2B3/SH3BGR/ADAP2/SH3BGRL/SORBS1	42
MF	GO:0032934	sterol binding	12/2603	56/17697	0.1119	0.4398	0.3909	OSBPL3/RORA/ERLIN2/GPR183/GRAMD1C/APOE/OSBPL8/CD81/TSPO/SCP2/NFE2L1/NPC1	12
MF	GO:0016298	lipase activity	24/2603	127/17697	0.1149	0.449	0.3991	PNPLA4/PNPLA6/CCL5/LIPC/PLCG2/ABHD6/PLA2G2D/PLA2G15/PRDX6/CCR5/PLD3/PLA2G7/GDPD5/PLD1/GDE1/CES3/PLA2G4C/PLA1A/PLCE1/LIPA/PLCD1/LPL/PLBD1/ABHD2	24
MF	GO:0034062	5'-3' RNA polymerase activity	10/2603	45/17697	0.1154	0.449	0.3991	POLR2J/POLR2I/POLR2L/POLR3C/POLR2E/POLR2F/POLR2C/POLR1B/POLR2G/POLR1C	10
MF	GO:0097747	RNA polymerase activity	10/2603	45/17697	0.1154	0.449	0.3991	POLR2J/POLR2I/POLR2L/POLR3C/POLR2E/POLR2F/POLR2C/POLR1B/POLR2G/POLR1C	10
MF	GO:0008236	serine-type peptidase activity	33/2603	182/17697	0.1158	0.449	0.3991	TPSAB1/TPSB2/GZMH/PREPL/PCSK1/HGF/CTSA/CFD/NAALAD2/HTRA1/PCSK7/GZMB/TPSD1/CMA1/CPD/GZMA/CFI/KLK14/ELANE/SEC11A/GZMK/MBTPS1/KLK8/TPP2/CTSG/TPSG1/TMPRSS5/NUP98/DPP8/PRSS16/PREP/CORIN/DPP6	33
MF	GO:0035591	signaling adaptor activity	16/2603	80/17697	0.1209	0.4673	0.4153	SH2B2/ITSN2/SH2D2A/NCK2/CHN1/CD28/GRB10/SHB/TRAT1/TP53BP2/LAT/AKAP13/SH2B3/SH3BGR/SH3BGRL/SORBS1	16
MF	GO:0016675	oxidoreductase activity, acting on a heme group of donors	7/2603	29/17697	0.1231	0.4679	0.4159	COX7A1/NDUFA4L2/NDUFA4/COX6C/COX8A/COX6A1/COX5B	7
MF	GO:0032947	protein-containing complex scaffold activity	7/2603	29/17697	0.1231	0.4679	0.4159	NCK2/MMS19/MAGI2/CD3E/AKAP13/CD3G/NUP62	7
MF	GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	7/2603	29/17697	0.1231	0.4679	0.4159	DHRS9/HSD11B2/HSD17B10/HSD17B1/AKR1C3/HSD17B14/AKR1C4	7
MF	GO:0035035	histone acetyltransferase binding	7/2603	29/17697	0.1231	0.4679	0.4159	STAT1/EID1/EGR1/TAF7/HIF1A/CREB1/CEBPB	7
MF	GO:0004197	cysteine-type endopeptidase activity	22/2603	116/17697	0.1233	0.4679	0.4159	SFRP1/LGMN/USP11/CTSW/USP46/MALT1/UCHL1/CFLAR/USP24/CASP4/CTSF/CAPNS1/CTSO/USP47/USP34/CASP9/USP8/USP9X/USP12/ATG4A/USP48/USP14	22
MF	GO:0060590	ATPase regulator activity	9/2603	40/17697	0.1235	0.4679	0.4159	ATP1B1/SIL1/HSPH1/DNAJC1/DNAJA1/NCAPH/TOR1AIP1/BAG1/DNAJC24	9
MF	GO:0051536	iron-sulfur cluster binding	13/2603	63/17697	0.1265	0.476	0.4231	FECH/TYW1/GLRX5/DNA2/IREB2/FDX1/DDX11/NUBPL/ELP3/NUBP2/ERCC2/NFU1/NDUFS7	13
MF	GO:0051540	metal cluster binding	13/2603	63/17697	0.1265	0.476	0.4231	FECH/TYW1/GLRX5/DNA2/IREB2/FDX1/DDX11/NUBPL/ELP3/NUBP2/ERCC2/NFU1/NDUFS7	13
MF	GO:0019865	immunoglobulin binding	6/2603	24/17697	0.1299	0.4848	0.4309	FCGRT/MS4A2/FCER1A/LILRA2/LGALS3/MS4A1	6
MF	GO:0051119	sugar transmembrane transporter activity	6/2603	24/17697	0.1299	0.4848	0.4309	SLC2A3/SLC2A6/SLC5A3/SLC2A11/SLC2A9/SLC2A5	6
MF	GO:0034212	peptide N-acetyltransferase activity	15/2603	75/17697	0.1301	0.4848	0.4309	NCOA3/TADA3/TAF10/NAA16/BRPF1/NAA50/ELP3/BRCA2/TAF9B/KAT6A/KAT5/OGT/KAT2B/ATF2/EP300	15
MF	GO:0003678	DNA helicase activity	16/2603	81/17697	0.1312	0.4872	0.4331	SETX/CHD1/CHD8/NBN/RECQL/DNA2/DDX11/GINS1/ASCC3/ATRX/RAD50/CHD3/RUVBL2/WRN/ERCC2/RFC2	16
MF	GO:0001103	RNA polymerase II repressing transcription factor binding	8/2603	35/17697	0.1322	0.4882	0.434	TCERG1/PPARG/BBS1/BBS4/GTF2A2/RBPJ/HDAC1/TCF7L2	8
MF	GO:1990782	protein tyrosine kinase binding	18/2603	93/17697	0.1323	0.4882	0.434	TREM2/SH2B2/ANGPT1/ITGAX/ANGPT2/NEDD9/PHYHIP/PTPN2/CBLB/CDH5/TRAT1/CD247/MYOC/EPHA4/EIF3A/CD2/SH2B3/DSCAM	18
MF	GO:0050661	NADP binding	11/2603	52/17697	0.1332	0.4899	0.4355	QDPR/LBR/HSD17B1/CAT/NOS3/GMDS/GRHPR/CRYZ/FMO3/DHCR7/FMO4	11
MF	GO:0030296	protein tyrosine kinase activator activity	5/2603	19/17697	0.1357	0.4958	0.4407	CCL5/EGF/EFNA5/ABI1/PAK2	5
MF	GO:0070300	phosphatidic acid binding	5/2603	19/17697	0.1357	0.4958	0.4407	MICALL1/PITPNC1/RAPGEF6/NRGN/GSDMD	5
MF	GO:0051539	4 iron, 4 sulfur cluster binding	9/2603	41/17697	0.1388	0.4961	0.441	TYW1/DNA2/IREB2/DDX11/NUBPL/NUBP2/ERCC2/NFU1/NDUFS7	9
MF	GO:0004707	MAP kinase activity	4/2603	14/17697	0.1388	0.4961	0.441	MAPK3/MAPK7/MAPK11/NLK	4
MF	GO:0005095	GTPase inhibitor activity	4/2603	14/17697	0.1388	0.4961	0.441	IQGAP2/ARL2/CDC42SE1/RHOH	4
MF	GO:0016846	carbon-sulfur lyase activity	4/2603	14/17697	0.1388	0.4961	0.441	LTC4S/ALOX5AP/MGST3/GLO1	4
MF	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	4/2603	14/17697	0.1388	0.4961	0.441	ECI2/ECH1/ECI1/DCT	4
MF	GO:0036041	long-chain fatty acid binding	4/2603	14/17697	0.1388	0.4961	0.441	ALOX5AP/PPARG/SCP2/FABP3	4
MF	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity	4/2603	14/17697	0.1388	0.4961	0.441	SOCS6/SOCS1/PIK3R5/CISH	4
MF	GO:0030332	cyclin binding	7/2603	30/17697	0.1414	0.5022	0.4464	GAK/FBXW7/CDK4/INSM1/CDK1/CDKN1A/CDK9	7
MF	GO:0070273	phosphatidylinositol-4-phosphate binding	7/2603	30/17697	0.1414	0.5022	0.4464	ARFIP1/GSDMB/SNX24/OSBPL8/RS1/GSDMD/GOLPH3	7
MF	GO:0017171	serine hydrolase activity	33/2603	186/17697	0.1428	0.5058	0.4496	TPSAB1/TPSB2/GZMH/PREPL/PCSK1/HGF/CTSA/CFD/NAALAD2/HTRA1/PCSK7/GZMB/TPSD1/CMA1/CPD/GZMA/CFI/KLK14/ELANE/SEC11A/GZMK/MBTPS1/KLK8/TPP2/CTSG/TPSG1/TMPRSS5/NUP98/DPP8/PRSS16/PREP/CORIN/DPP6	33
MF	GO:0017069	snRNA binding	10/2603	47/17697	0.1435	0.5068	0.4505	LSM4/SART3/ISG20/CCNT2/DDX21/RBM41/NCBP2/CDK9/MEPCE/LSM2	10
MF	GO:0005088	Ras guanyl-nucleotide exchange factor activity	25/2603	137/17697	0.1465	0.5157	0.4584	DENND3/ECT2/RASGRP1/RGL1/ARHGEF3/SOS1/ARHGEF40/ITSN2/EGF/ARHGEF9/RASGRP3/DENND4B/MADD/ARHGEF2/DENND1B/DENND4A/ARHGEF7/DENND1C/NET1/DOCK3/RANGRF/AKAP13/EPS8L2/RAB3IL1/MCF2L	25
MF	GO:0001671	ATPase activator activity	6/2603	25/17697	0.1508	0.5272	0.4686	ATP1B1/DNAJC1/DNAJA1/NCAPH/TOR1AIP1/DNAJC24	6
MF	GO:0023023	MHC protein complex binding	6/2603	25/17697	0.1508	0.5272	0.4686	ATP1B1/LILRB2/CD8A/CD81/HLA-DOB/MS4A1	6
MF	GO:0003684	damaged DNA binding	13/2603	65/17697	0.1512	0.5272	0.4686	DCLRE1C/ERCC1/NBN/TDG/RPA1/RPA3/MPG/HMGB1/DDB2/RAD1/WRN/ERCC2/EP300	13
MF	GO:0005516	calmodulin binding	35/2603	200/17697	0.1538	0.5347	0.4753	SPHK1/IQGAP2/KCNN3/SNTA1/KCNQ1/ASPM/FAS/RGS1/PDE1A/EGFR/MARCKSL1/FBXL2/RGS4/ATP2B2/NOS3/ADCY1/IQCB1/MAPKAPK2/PPP3CA/VAMP2/CAMK1/MKNK2/NRGN/REM1/KCNN2/MYH4/ATP2B4/NGFR/SYT1/SNTB1/UBR4/KCNQ3/CAMK2B/MYH10/ATP2B1	35
MF	GO:0016791	phosphatase activity	46/2603	270/17697	0.1581	0.5472	0.4864	PTPRE/CDC25B/DUSP5/HDDC2/EYA2/PPP1R3C/DUSP6/EPHX2/MTMR4/PTPRF/PTPRC/G6PC3/NT5C2/DLGAP5/SYNJ1/PIKFYVE/PTPN7/CTDSPL/RNGTT/MTMR6/PTPN22/SHOC2/PPP4R1/CDC14A/PFKFB3/PTPN2/SSH3/LCK/PPM1E/PTPRN2/CTDP1/PSPH/MTMR1/DUSP2/ACP6/PPP3CA/PPM1B/PTPRK/ACP1/NT5E/INPP5E/PTPRH/PHLPP1/STYXL1/LPIN1/PPA2	46
MF	GO:0001091	RNA polymerase II basal transcription factor binding	5/2603	20/17697	0.1602	0.5472	0.4864	AR/ERCC1/CTDP1/TAF7/RUVBL2	5
MF	GO:0008157	protein phosphatase 1 binding	5/2603	20/17697	0.1602	0.5472	0.4864	KCNQ1/LILRB2/SHOC2/PHACTR4/STAU1	5
MF	GO:0016408	C-acyltransferase activity	5/2603	20/17697	0.1602	0.5472	0.4864	ACSM5/GCAT/ACAT1/SCP2/ACAA2	5
MF	GO:0048018	receptor ligand activity	79/2603	482/17697	0.1606	0.5472	0.4864	CXCL9/EFEMP1/CXCL10/PTN/CD320/TNFRSF11B/CCL5/SECTM1/IL32/CRLF1/SEMA4D/THNSL2/CXCL13/PGF/THBS4/CCL18/IL15/CXCL11/SEMA4A/BTC/HGF/FGF14/SEMA3A/FGF13/EGF/STC1/NTF3/CXCL2/BMP4/GDF5/FGF20/SEMA4C/PENK/EFNA5/TYMP/CTF1/RABEP2/CCL8/IFNG/AGT/SEMA3F/IGF1/FGF18/NBL1/HCRT/IL6/HBEGF/NAMPT/EREG/PDGFB/XCL1/VEGFA/TNFSF4/HMGB1/PNOC/CXCL3/SCG2/SEMA3E/CCL13/TNFSF8/AGRP/JAG2/NMB/IL1RN/GDF9/IL6R/TNFSF14/GAL/LGALS3/TIMP1/CCL7/INHBB/CXCL8/FGF5/CD40LG/IL22/BDNF/STC2/VEGFB	79
MF	GO:0140142	nucleocytoplasmic carrier activity	7/2603	31/17697	0.1608	0.5472	0.4864	XPO6/KPNA2/SNUPN/TNPO1/KPNB1/KPNA1/KPNA3	7
MF	GO:0030170	pyridoxal phosphate binding	11/2603	54/17697	0.1615	0.5472	0.4864	CBS/SDS/THNSL2/GOT1/PNPO/GCAT/PYGM/HDC/OAT/SRR/SGPL1	11
MF	GO:0070279	vitamin B6 binding	11/2603	54/17697	0.1615	0.5472	0.4864	CBS/SDS/THNSL2/GOT1/PNPO/GCAT/PYGM/HDC/OAT/SRR/SGPL1	11
MF	GO:0016279	protein-lysine N-methyltransferase activity	12/2603	60/17697	0.1633	0.5472	0.4864	SUZ12/EZH2/METTL22/SETD5/SETMAR/SMYD2/SETD1B/VCPKMT/EED/SETD2/SUV39H2/CXXC1	12
MF	GO:0008170	N-methyltransferase activity	18/2603	96/17697	0.1637	0.5472	0.4864	SUZ12/PEMT/EZH2/METTL22/PRMT5/SETD5/SETMAR/SMYD2/SETD1B/VCPKMT/EED/DIMT1/HEMK1/SETD2/SUV39H2/HNMT/CXXC1/TFB2M	18
MF	GO:0015144	carbohydrate transmembrane transporter activity	8/2603	37/17697	0.1675	0.5472	0.4864	SLC2A3/SLC2A6/SLC5A3/SLC2A11/SLC2A9/SLC2A5/AQP2/SLC2A10	8
MF	GO:0042162	telomeric DNA binding	8/2603	37/17697	0.1675	0.5472	0.4864	HNRNPA2B1/RPA1/HMBOX1/HNRNPA1/RAD50/NABP2/WRN/HNRNPD	8
MF	GO:0004559	alpha-mannosidase activity	4/2603	15/17697	0.1684	0.5472	0.4864	MAN2B2/MAN1C1/MAN1B1/EDEM1	4
MF	GO:0004953	icosanoid receptor activity	4/2603	15/17697	0.1684	0.5472	0.4864	HPGD/PPARG/PTGER4/PTGFR	4
MF	GO:0005545	1-phosphatidylinositol binding	4/2603	15/17697	0.1684	0.5472	0.4864	ZFYVE16/SCIN/SNX10/SYT1	4
MF	GO:0016805	dipeptidase activity	4/2603	15/17697	0.1684	0.5472	0.4864	PEPD/NAALAD2/SCRN1/CPQ	4
MF	GO:0017160	Ral GTPase binding	4/2603	15/17697	0.1684	0.5472	0.4864	RGL1/EXOC2/FLNA/LSM2	4
MF	GO:0042809	vitamin D receptor binding	4/2603	15/17697	0.1684	0.5472	0.4864	MED13/RXRA/MED1/TAF7	4
MF	GO:0008168	methyltransferase activity	37/2603	215/17697	0.1717	0.5472	0.4864	BHMT2/SUZ12/GAMT/PEMT/DNMT1/EZH2/COMT/METTL8/TARBP1/METTL22/PRMT5/CMTR1/SETD5/LCMT1/SETMAR/TRMT112/SMYD2/SETD1B/METTL4/PRDM1/VCPKMT/EED/DIMT1/HEMK1/SETD2/PRDM4/SUV39H2/TYMS/PRDM10/HNMT/CXXC1/TFB2M/TRMT5/METTL5/MEPCE/NSUN6/TRMT13	37
MF	GO:0005165	neurotrophin receptor binding	3/2603	10/17697	0.1722	0.5472	0.4864	NTF3/EFNA5/NTRK1	3
MF	GO:0005351	carbohydrate:proton symporter activity	3/2603	10/17697	0.1722	0.5472	0.4864	SLC2A6/SLC2A9/SLC2A10	3
MF	GO:0008121	ubiquinol-cytochrome-c reductase activity	3/2603	10/17697	0.1722	0.5472	0.4864	UQCR10/UQCRQ/UQCRC1	3
MF	GO:0010857	calcium-dependent protein kinase activity	3/2603	10/17697	0.1722	0.5472	0.4864	PINK1/MAPKAPK2/MKNK2	3
MF	GO:0015924	mannosyl-oligosaccharide mannosidase activity	3/2603	10/17697	0.1722	0.5472	0.4864	MAN1C1/MAN1B1/EDEM1	3
MF	GO:0016681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor	3/2603	10/17697	0.1722	0.5472	0.4864	UQCR10/UQCRQ/UQCRC1	3
MF	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	3/2603	10/17697	0.1722	0.5472	0.4864	CPS1/NADSYN1/ASNS	3
MF	GO:0035615	clathrin adaptor activity	3/2603	10/17697	0.1722	0.5472	0.4864	AP2M1/ARRB1/HIP1R	3
MF	GO:0051400	BH domain binding	3/2603	10/17697	0.1722	0.5472	0.4864	BCL2A1/MCL1/BCL2L2	3
MF	GO:0070513	death domain binding	3/2603	10/17697	0.1722	0.5472	0.4864	DAP/CRADD/MCL1	3
MF	GO:0098748	endocytic adaptor activity	3/2603	10/17697	0.1722	0.5472	0.4864	AP2M1/ARRB1/HIP1R	3
MF	GO:0004435	phosphatidylinositol phospholipase C activity	6/2603	26/17697	0.1732	0.5472	0.4864	CCL5/PLCG2/CCR5/GDPD5/PLCE1/PLCD1	6
MF	GO:0043015	gamma-tubulin binding	6/2603	26/17697	0.1732	0.5472	0.4864	NDN/RACGAP1/BRCA2/TUBGCP5/OFD1/TUBGCP2	6
MF	GO:0051019	mitogen-activated protein kinase binding	6/2603	26/17697	0.1732	0.5472	0.4864	GCH1/TNIP1/TPR/MAPK7/DUSP2/MAPKAPK2	6
MF	GO:0015485	cholesterol binding	10/2603	49/17697	0.1749	0.5512	0.4899	OSBPL3/ERLIN2/GRAMD1C/APOE/OSBPL8/CD81/TSPO/SCP2/NFE2L1/NPC1	10
MF	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	28/2603	159/17697	0.1763	0.5536	0.4921	PTGS1/P4HTM/MICAL1/TBXAS1/CH25H/PCBD1/KDM2A/FTO/PHYH/CYP11A1/CYP7B1/COQ6/ASPH/MOXD1/KDM7A/HSPBAP1/SC5D/JMJD6/MICAL2/NOS3/SCD5/AKR1C3/EGLN3/FMO3/CYP4F11/FMO4/AKR1C4/TH	28
MF	GO:0004175	endopeptidase activity	70/2603	427/17697	0.1766	0.5536	0.4921	SFRP1/TPSAB1/TPSB2/LGMN/ADAMDEC1/ADAM19/GZMH/USP11/CTSW/USP46/MALT1/PREPL/PCSK1/UCHL1/CFLAR/PSMB9/HGF/ADAM17/USP24/ADAM23/CFD/CASP4/CTSF/CAPNS1/HTRA1/IDE/PCSK7/GZMB/TPSD1/CTSO/CMA1/USP47/GZMA/CFI/KLK14/ADAM22/ELANE/USP34/PSMB6/GZMK/MBTPS1/KLK8/PAPPA/TMEM59/MMP13/CPS1/MMP12/CASP9/USP8/ADAMTS3/TASP1/PSMB5/USP9X/TPP2/USP12/MMP20/ATG4A/APH1B/USP48/CTSG/TPSG1/ADAMTS8/MIPEP/YME1L1/TMPRSS5/APH1A/ADAM28/PREP/USP14/CORIN	70
MF	GO:0016278	lysine N-methyltransferase activity	12/2603	61/17697	0.1778	0.5539	0.4924	SUZ12/EZH2/METTL22/SETD5/SETMAR/SMYD2/SETD1B/VCPKMT/EED/SETD2/SUV39H2/CXXC1	12
MF	GO:0005518	collagen binding	13/2603	67/17697	0.1782	0.5539	0.4924	SMAD3/MRC2/SPOCK1/PCOLCE/CD44/COMP/PCOLCE2/MMP13/PDGFB/MMP12/COL5A3/SPOCK2/PPIB	13
MF	GO:0019210	kinase inhibitor activity	13/2603	67/17697	0.1782	0.5539	0.4924	PRKAR2A/CDKN2C/SOCS1/FGFR1OP/HSPB1/TRIB1/CDKN1C/DNAJC3/TAOK3/CIB1/RHOH/KAT2B/CDKN1A	13
MF	GO:0016758	transferase activity, transferring hexosyl groups	37/2603	216/17697	0.1793	0.5558	0.494	MGAT4C/GALNT11/GALNT10/SDF2/EOGT/B4GALT2/EXT2/PIGA/PIGP/B3GALNT1/FUT1/DPM3/RFNG/TYMP/UGCG/GCNT3/DPY19L2P2/PYGM/HEXA/POFUT1/EXTL2/UGT2B17/DAD1/B4GALT7/GALNT3/PIGH/FUT8/DDOST/ALG6/OGT/HAS2/PIGZ/PIGC/ABO/FUT4/C1GALT1C1/B4GALT3	37
MF	GO:0030291	protein serine/threonine kinase inhibitor activity	7/2603	32/17697	0.1813	0.5591	0.497	PRKAR2A/CDKN2C/HSPB1/CDKN1C/CIB1/KAT2B/CDKN1A	7
MF	GO:1904680	peptide transmembrane transporter activity	7/2603	32/17697	0.1813	0.5591	0.497	TAP1/TAPBP/ABCC1/TAP2/SEC61A2/MCL1/SLC15A2	7