ONTOLOGY	ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	qvalue	geneID	Count
BP	GO:0042110	T cell activation	137/2112	464/18670	2.974e-27	1.839e-23	1.329e-23	CCL5/ITK/CD3D/LCP1/RELB/PLA2G2D/XCL1/LCK/PIK3R1/CD3E/PTPRC/CTLA4/CD2/CCR2/BMP4/BCL11B/IRF1/RUNX3/IGF1/CORO1A/SEMA4A/RASGRP1/CSK/IDO1/TNFRSF1B/CD7/DLG5/CD8A/LILRB2/RAC2/PRKCQ/GPR183/PSMB10/CCL19/ZBTB16/IL15/IL7R/ELF4/BATF/GLI3/LAT/PPP3CA/CCR7/SIRPG/SASH3/IRF4/CD74/PTPN2/TCIRG1/CD3G/IL4R/CD5/HLA-G/ICAM1/LGALS9/NOD2/MALT1/ADAM8/MICB/TNFRSF14/SOCS1/MAP3K8/TWSG1/RIPK2/TFRC/BTN2A2/HLA-E/ADA/PTPN6/GPR18/ITGAL/CLEC7A/ZAP70/CR1/HLA-DPB1/CD160/CCL21/WAS/CLEC4E/ERBB2/TCF7/RHOH/TBX21/PDCD1LG2/LILRB4/CD27/CD40LG/NCKAP1L/PIK3CD/SOD1/CD86/CD83/CD6/LEF1/HLA-DMB/ICOS/SMAD3/RAB27A/PTPN11/FZD7/DOCK2/VAV1/LEP/IL6ST/ZFP36L1/IFNG/CLEC4A/SOCS6/PIK3CA/PNP/PTGER4/FAM49B/PAK1/SYK/CD80/BTN3A1/ICOSLG/HFE/TNFRSF4/IL6/PTPN22/HLA-DPA1/IL18/LYN/IGFBP2/CD81/ZFP36L2/SPINK5/LRRC32/IL2RA/TP53/CCL2/IFNA1/GSN/IL1B/LILRB1/NLRP3	137
BP	GO:0045785	positive regulation of cell adhesion	120/2112	403/18670	2.421e-24	7.484e-21	5.407e-21	CCL5/CXCL13/XCL1/LCK/PIK3R1/NDNF/CD3E/SFRP1/PTPRC/CTLA4/CCR2/RUNX3/IGF1/CORO1A/RASGRP1/CSK/LILRB2/SPOCK2/PRKCQ/ADAM19/CCL19/ZBTB16/IL15/IL7R/ITGA4/GLI3/PPP3CA/CCR7/SIRPG/SASH3/EMP2/ANGPT1/ZFHX3/CD74/ITGB1BP1/ITGB2/ECM2/IL4R/CD5/HLA-G/ICAM1/LGALS9/NOD2/MALT1/ADAM8/DYSF/JAK2/CD36/PRKD2/TNFRSF14/SOCS1/MAP3K8/RIPK2/TFRC/BTN2A2/HLA-E/PDPN/ADA/DAG1/PTPN6/ZAP70/HLA-DPB1/COL8A1/CD160/CCL21/ERBB2/PDCD1LG2/EDIL3/SOX2/LILRB4/CD27/CD40LG/PTN/DOCK1/NCKAP1L/SKAP1/CD86/CD83/CD6/HYAL1/HLA-DMB/ICOS/SMAD3/PTPN11/HSD17B12/VAV1/MYOC/LEP/IL6ST/IFNG/PIK3CA/PPM1F/PNP/FAM49B/PAK1/STX4/SYK/CD80/PLEKHA2/ICOSLG/RHOD/IL6/HLA-DPA1/FERMT1/IL18/LYN/IGFBP2/FSTL3/KDR/CD81/TGM2/IL2RA/ITGAV/CCL2/LIMS2/COL16A1/VAV3/IL1B/LILRB1/NLRP3	120
BP	GO:0007159	leukocyte cell-cell adhesion	106/2112	337/18670	1.075e-23	2.132e-20	1.541e-20	CCL5/PLA2G2D/XCL1/LCK/PIK3R1/CD3E/PTPRC/CTLA4/CCR2/STK10/S100A9/BMP4/IRF1/RUNX3/IGF1/CORO1A/RASGRP1/CSK/NT5E/IDO1/ITGB7/DLG5/LILRB2/RAC2/PRKCQ/CCL19/ZBTB16/IL15/IL7R/ITGA4/SEMA4D/GLI3/CCR7/SIRPG/SASH3/CD74/PTPN2/ITGB2/IL4R/CD5/HLA-G/ICAM1/LGALS9/SELL/NOD2/MALT1/ADAM8/TNFRSF14/SOCS1/MAP3K8/TWSG1/RIPK2/TFRC/BTN2A2/HLA-E/ADA/PTPN6/ITGAL/ZAP70/SELE/HLA-DPB1/CD160/CCL21/ERBB2/TBX21/PDCD1LG2/CX3CR1/LILRB4/CD27/CD40LG/NCKAP1L/SKAP1/CD86/CD83/CD6/HLA-DMB/ICOS/PTPN11/VAV1/LEP/IL6ST/IFNG/PECAM1/SOCS6/PIK3CA/PNP/FAM49B/PAK1/SYK/CD80/ICOSLG/HFE/IL6/PTPN22/SELPLG/HLA-DPA1/IL18/LYN/IGFBP2/CD81/LRRC32/IL2RA/CCL2/IL1B/LILRB1/NLRP3	106
BP	GO:1903039	positive regulation of leukocyte cell-cell adhesion	81/2112	218/18670	1.38e-23	2.132e-20	1.541e-20	CCL5/XCL1/LCK/PIK3R1/CD3E/PTPRC/CTLA4/CCR2/RUNX3/IGF1/CORO1A/RASGRP1/CSK/LILRB2/PRKCQ/CCL19/ZBTB16/IL15/IL7R/ITGA4/GLI3/CCR7/SIRPG/SASH3/CD74/ITGB2/IL4R/CD5/HLA-G/ICAM1/LGALS9/NOD2/MALT1/ADAM8/TNFRSF14/SOCS1/MAP3K8/RIPK2/TFRC/BTN2A2/HLA-E/ADA/PTPN6/ZAP70/HLA-DPB1/CD160/CCL21/PDCD1LG2/LILRB4/CD27/CD40LG/NCKAP1L/SKAP1/CD86/CD83/CD6/HLA-DMB/ICOS/PTPN11/VAV1/LEP/IL6ST/IFNG/PIK3CA/PNP/FAM49B/PAK1/SYK/CD80/ICOSLG/IL6/HLA-DPA1/IL18/LYN/IGFBP2/CD81/IL2RA/CCL2/IL1B/LILRB1/NLRP3	81
BP	GO:0050870	positive regulation of T cell activation	77/2112	202/18670	2.701e-23	3.341e-20	2.414e-20	CCL5/XCL1/LCK/PIK3R1/CD3E/PTPRC/CTLA4/CCR2/RUNX3/IGF1/CORO1A/RASGRP1/CSK/LILRB2/PRKCQ/CCL19/ZBTB16/IL15/IL7R/GLI3/CCR7/SIRPG/SASH3/CD74/IL4R/CD5/HLA-G/LGALS9/NOD2/MALT1/ADAM8/TNFRSF14/SOCS1/MAP3K8/RIPK2/TFRC/BTN2A2/HLA-E/ADA/PTPN6/ZAP70/HLA-DPB1/CD160/CCL21/PDCD1LG2/LILRB4/CD27/CD40LG/NCKAP1L/CD86/CD83/CD6/HLA-DMB/ICOS/PTPN11/VAV1/LEP/IL6ST/IFNG/PIK3CA/PNP/FAM49B/PAK1/SYK/CD80/ICOSLG/IL6/HLA-DPA1/IL18/LYN/IGFBP2/CD81/IL2RA/CCL2/IL1B/LILRB1/NLRP3	77
BP	GO:0050863	regulation of T cell activation	99/2112	314/18670	2.714e-22	2.797e-19	2.021e-19	CCL5/PLA2G2D/XCL1/LCK/PIK3R1/CD3E/PTPRC/CTLA4/CD2/CCR2/BMP4/IRF1/RUNX3/IGF1/CORO1A/RASGRP1/CSK/IDO1/TNFRSF1B/DLG5/LILRB2/RAC2/PRKCQ/CCL19/ZBTB16/IL15/IL7R/GLI3/LAT/CCR7/SIRPG/SASH3/IRF4/CD74/PTPN2/IL4R/CD5/HLA-G/LGALS9/NOD2/MALT1/ADAM8/TNFRSF14/SOCS1/MAP3K8/TWSG1/RIPK2/TFRC/BTN2A2/HLA-E/ADA/PTPN6/ZAP70/CR1/HLA-DPB1/CD160/CCL21/ERBB2/TBX21/PDCD1LG2/LILRB4/CD27/CD40LG/NCKAP1L/SOD1/CD86/CD83/CD6/HLA-DMB/ICOS/PTPN11/VAV1/LEP/IL6ST/IFNG/SOCS6/PIK3CA/PNP/FAM49B/PAK1/SYK/CD80/ICOSLG/HFE/IL6/PTPN22/HLA-DPA1/IL18/LYN/IGFBP2/CD81/SPINK5/LRRC32/IL2RA/CCL2/GSN/IL1B/LILRB1/NLRP3	99
BP	GO:0051249	regulation of lymphocyte activation	131/2112	485/18670	3.395e-22	2.999e-19	2.167e-19	CCL5/SLAMF8/PLA2G2D/TRBC1/XCL1/LCK/PIK3R1/CD3E/SFRP1/PTPRC/CTLA4/TNFAIP3/CD2/CCR2/BMP4/IRF1/IL27RA/RUNX3/IGF1/CORO1A/RASGRP1/CSK/IDO1/HLA-F/TNFRSF1B/DLG5/LILRB2/RAC2/PRKCQ/GPR183/CCL19/ZBTB16/IL15/IL7R/GLI3/LAT/INHBA/CCR7/SIRPG/SASH3/IRF4/CD74/AXL/PTPN2/IL4R/CD5/HLA-G/LGALS9/NOD2/MALT1/ADAM8/TNIP2/SAMSN1/CD40/TNFRSF14/SOCS1/MAP3K8/TWSG1/RIPK2/TFRC/BTN2A2/HLA-E/ADA/PTPN6/CLEC7A/TAC1/ZAP70/CR1/IGHM/IGLL5/HLA-DPB1/CD160/CCL21/ERBB2/TBX21/PDCD1LG2/LILRB4/CD27/CD40LG/NCKAP1L/SOD1/CD86/CD83/CD6/CD19/HLA-DMB/ICOS/TOX/PTPN11/VAV1/LEP/IL6ST/ZFP36L1/MNDA/IFNG/IGLC1/SOCS6/PIK3CA/PNP/FAM49B/PAK1/SYK/CD80/ICOSLG/HFE/BTK/TNFRSF4/IL6/PTPN22/CD38/IGHG1/INPP5D/HLA-DPA1/CD320/LST1/IL18/LYN/IGFBP2/CD81/MERTK/ZFP36L2/SPINK5/THOC1/LRRC32/IL2RA/CCL2/GSN/VAV3/IL1B/LILRB1/NLRP3	131
BP	GO:0022409	positive regulation of cell-cell adhesion	86/2112	255/18670	1.108e-21	8.562e-19	6.186e-19	CCL5/CXCL13/XCL1/LCK/PIK3R1/CD3E/PTPRC/CTLA4/CCR2/RUNX3/IGF1/CORO1A/RASGRP1/CSK/LILRB2/PRKCQ/ADAM19/CCL19/ZBTB16/IL15/IL7R/ITGA4/GLI3/CCR7/SIRPG/SASH3/CD74/ITGB2/IL4R/CD5/HLA-G/ICAM1/LGALS9/NOD2/MALT1/ADAM8/TNFRSF14/SOCS1/MAP3K8/RIPK2/TFRC/BTN2A2/HLA-E/PDPN/ADA/PTPN6/ZAP70/HLA-DPB1/CD160/CCL21/PDCD1LG2/SOX2/LILRB4/CD27/CD40LG/NCKAP1L/SKAP1/CD86/CD83/CD6/HLA-DMB/ICOS/PTPN11/VAV1/LEP/IL6ST/IFNG/PIK3CA/PNP/FAM49B/PAK1/SYK/CD80/ICOSLG/IL6/HLA-DPA1/IL18/LYN/IGFBP2/FSTL3/CD81/IL2RA/CCL2/IL1B/LILRB1/NLRP3	86
BP	GO:0050867	positive regulation of cell activation	112/2112	394/18670	5.149e-21	3.537e-18	2.556e-18	CCL5/TRBC1/XCL1/LCK/PIK3R1/CD3E/PTPRC/CTLA4/CD2/CCR2/RUNX3/IGF1/CORO1A/RASGRP1/CSK/HLA-F/LILRB2/PRKCQ/GPR183/CCL19/ZBTB16/IL15/IL7R/GLI3/CCR7/SIRPG/SASH3/CD74/AXL/ITGB2/IL4R/CD5/HLA-G/LGALS9/NOD2/MALT1/ADAM8/TNIP2/JAK2/CTSC/CD40/TNFRSF14/SOCS1/MAP3K8/GATA2/RIPK2/RPS6KA1/FGR/TFRC/BTN2A2/HLA-E/PDPN/ADA/PTPN6/CLEC7A/TAC1/ZAP70/IGHM/IGLL5/HLA-DPB1/CD160/CCL21/PLEK/CD226/TBX21/PDCD1LG2/LILRB4/CD27/CD40LG/NCKAP1L/CD86/CD83/CD6/HLA-DMB/ICOS/TOX/PTPN11/VAV1/LEP/IL6ST/IFNG/IGLC1/PIK3CA/PNP/FAM49B/PAK1/STX4/SYK/CD80/ICOSLG/STXBP1/BTK/TNFRSF4/IL6/CD38/IGHG1/INPP5D/HLA-DPA1/CD320/IL18/GAB2/LYN/CEBPA/IGFBP2/CD81/IL2RA/CCL2/TLR6/VAV3/IL1B/LILRB1/NLRP3	112
BP	GO:1903037	regulation of leukocyte cell-cell adhesion	94/2112	304/18670	1.435e-20	8.875e-18	6.412e-18	CCL5/PLA2G2D/XCL1/LCK/PIK3R1/CD3E/PTPRC/CTLA4/CCR2/BMP4/IRF1/RUNX3/IGF1/CORO1A/RASGRP1/CSK/IDO1/DLG5/LILRB2/PRKCQ/CCL19/ZBTB16/IL15/IL7R/ITGA4/GLI3/CCR7/SIRPG/SASH3/CD74/PTPN2/ITGB2/IL4R/CD5/HLA-G/ICAM1/LGALS9/NOD2/MALT1/ADAM8/TNFRSF14/SOCS1/MAP3K8/TWSG1/RIPK2/TFRC/BTN2A2/HLA-E/ADA/PTPN6/ZAP70/HLA-DPB1/CD160/CCL21/ERBB2/TBX21/PDCD1LG2/LILRB4/CD27/CD40LG/NCKAP1L/SKAP1/CD86/CD83/CD6/HLA-DMB/ICOS/PTPN11/VAV1/LEP/IL6ST/IFNG/SOCS6/PIK3CA/PNP/FAM49B/PAK1/SYK/CD80/ICOSLG/HFE/IL6/PTPN22/HLA-DPA1/IL18/LYN/IGFBP2/CD81/LRRC32/IL2RA/CCL2/IL1B/LILRB1/NLRP3	94
BP	GO:0002696	positive regulation of leukocyte activation	108/2112	380/18670	2.678e-20	1.505e-17	1.088e-17	CCL5/TRBC1/XCL1/LCK/PIK3R1/CD3E/PTPRC/CTLA4/CD2/CCR2/RUNX3/IGF1/CORO1A/RASGRP1/CSK/HLA-F/LILRB2/PRKCQ/GPR183/CCL19/ZBTB16/IL15/IL7R/GLI3/CCR7/SIRPG/SASH3/CD74/AXL/ITGB2/IL4R/CD5/HLA-G/LGALS9/NOD2/MALT1/ADAM8/TNIP2/CTSC/CD40/TNFRSF14/SOCS1/MAP3K8/GATA2/RIPK2/FGR/TFRC/BTN2A2/HLA-E/ADA/PTPN6/CLEC7A/TAC1/ZAP70/IGHM/IGLL5/HLA-DPB1/CD160/CCL21/CD226/TBX21/PDCD1LG2/LILRB4/CD27/CD40LG/NCKAP1L/CD86/CD83/CD6/HLA-DMB/ICOS/TOX/PTPN11/VAV1/LEP/IL6ST/IFNG/IGLC1/PIK3CA/PNP/FAM49B/PAK1/STX4/SYK/CD80/ICOSLG/STXBP1/BTK/TNFRSF4/IL6/CD38/IGHG1/INPP5D/HLA-DPA1/CD320/IL18/GAB2/LYN/CEBPA/IGFBP2/CD81/IL2RA/CCL2/TLR6/VAV3/IL1B/LILRB1/NLRP3	108
BP	GO:0051251	positive regulation of lymphocyte activation	97/2112	334/18670	4.608e-19	2.374e-16	1.716e-16	CCL5/TRBC1/XCL1/LCK/PIK3R1/CD3E/PTPRC/CTLA4/CCR2/RUNX3/IGF1/CORO1A/RASGRP1/CSK/HLA-F/LILRB2/PRKCQ/GPR183/CCL19/ZBTB16/IL15/IL7R/GLI3/CCR7/SIRPG/SASH3/CD74/AXL/IL4R/CD5/HLA-G/LGALS9/NOD2/MALT1/ADAM8/TNIP2/CD40/TNFRSF14/SOCS1/MAP3K8/RIPK2/TFRC/BTN2A2/HLA-E/ADA/PTPN6/CLEC7A/TAC1/ZAP70/IGHM/IGLL5/HLA-DPB1/CD160/CCL21/TBX21/PDCD1LG2/LILRB4/CD27/CD40LG/NCKAP1L/CD86/CD83/CD6/HLA-DMB/ICOS/TOX/PTPN11/VAV1/LEP/IL6ST/IFNG/IGLC1/PIK3CA/PNP/FAM49B/PAK1/SYK/CD80/ICOSLG/BTK/TNFRSF4/IL6/CD38/IGHG1/INPP5D/HLA-DPA1/CD320/IL18/LYN/IGFBP2/CD81/IL2RA/CCL2/VAV3/IL1B/LILRB1/NLRP3	97
BP	GO:0022407	regulation of cell-cell adhesion	109/2112	403/18670	1.06e-18	5.042e-16	3.643e-16	CCL5/CXCL13/PLA2G2D/XCL1/LCK/PIK3R1/CD3E/PTPRC/CTLA4/CCR2/BMP4/IRF1/RUNX3/IGF1/CORO1A/RASGRP1/CSK/IDO1/DLG5/LILRB2/PRKCQ/ADAM19/CCL19/ZBTB16/IL15/IL7R/ITGA4/GLI3/CCR7/SIRPG/SASH3/CD74/PTPN2/ITGB2/IL4R/CD5/HLA-G/ICAM1/LGALS9/NOD2/MALT1/ADAM8/JAK2/TNFRSF14/SOCS1/MAP3K8/TWSG1/RIPK2/TFRC/BTN2A2/HLA-E/PDPN/ADA/PTPN6/ZAP70/HLA-DPB1/CD160/CCL21/ERBB2/SPINT2/TBX21/PDCD1LG2/SOX2/LILRB4/CD27/CD40LG/NCKAP1L/SKAP1/CD86/CD83/CD6/LEF1/HLA-DMB/ICOS/EFNA5/PTPN11/VAV1/CD9/LEP/IL6ST/IFNG/SOCS6/PIK3CA/PPM1F/PNP/FAM49B/PAK1/ADIPOQ/SYK/CD80/ICOSLG/HFE/IL6/PTPN22/PRKG1/HLA-DPA1/IL18/IL1RN/LYN/SH2B3/IGFBP2/FSTL3/CD81/LRRC32/IL2RA/CCL2/IL1B/LILRB1/NLRP3	109
BP	GO:0046651	lymphocyte proliferation	84/2112	272/18670	1.765e-18	7.746e-16	5.597e-16	CCL5/PLA2G2D/XCL1/CD3E/PTPRC/CTLA4/CCR2/BMP4/IRF1/IGF1/CORO1A/IDO1/TNFRSF1B/DLG5/LILRB2/RAC2/PRKCQ/GPR183/PSMB10/CCL19/PURA/IL15/IL7R/ELF4/SASH3/CD74/HLA-G/LGALS9/MALT1/CD40/TNFRSF14/TWSG1/RIPK2/TFRC/BTN2A2/HLA-E/ADA/PTPN6/TAC1/ZAP70/HLA-DPB1/ERBB2/PDCD1LG2/CD40LG/NCKAP1L/MS4A1/CD86/CD6/CD19/LEF1/HLA-DMB/DOCK2/LEP/IL6ST/MNDA/FLT3/PNP/SYK/CD80/BTN3A1/ICOSLG/BTK/TNFRSF4/IL6/PTPN22/CD38/INPP5D/HLA-DPA1/CD180/CD320/LST1/HELLS/IL18/LYN/IGFBP2/CD81/LRRC32/IL2RA/TP53/IFNA1/VAV3/IL1B/CR2/LILRB1	84
BP	GO:0070661	leukocyte proliferation	89/2112	298/18670	1.879e-18	7.746e-16	5.597e-16	CCL5/PLA2G2D/KITLG/XCL1/CD3E/PTPRC/CTLA4/TNFAIP3/CCR2/BMP4/IRF1/IGF1/CORO1A/CLU/IDO1/TNFRSF1B/DLG5/LILRB2/RAC2/PRKCQ/GPR183/PSMB10/CCL19/PURA/IL15/IL7R/ELF4/SASH3/CD74/TCIRG1/HLA-G/LGALS9/MALT1/CD40/TNFRSF14/TWSG1/RIPK2/TFRC/BTN2A2/HLA-E/ADA/PTPN6/TAC1/ZAP70/HLA-DPB1/ERBB2/PDCD1LG2/CD40LG/NCKAP1L/MS4A1/CD86/CD6/CD19/LEF1/HLA-DMB/DOCK2/LEP/IL6ST/MNDA/FLT3/PNP/SYK/CD80/BTN3A1/ICOSLG/BTK/TNFRSF4/IL6/PTPN22/CD38/INPP5D/HLA-DPA1/CD180/CD320/LST1/HELLS/IL18/LYN/IGFBP2/CD81/NPR3/LRRC32/IL2RA/TP53/IFNA1/VAV3/IL1B/CR2/LILRB1	89
BP	GO:0030098	lymphocyte differentiation	99/2112	353/18670	2.869e-18	1.063e-15	7.682e-16	ITK/SLAMF8/CD3D/RELB/PLA2G2D/LCK/PIK3R1/CD3E/SFRP1/PTPRC/CTLA4/CD2/CCR2/BMP4/BCL11B/IRF1/RUNX3/SEMA4A/RASGRP1/CD8A/LILRB2/GPR183/CCL19/ZBTB16/IL15/IL7R/ITGA4/BATF/GLI3/DOCK10/INHBA/CCR7/SASH3/IRF4/CD74/AXL/PTPN2/TCIRG1/CD3G/IL4R/HLA-G/LGALS9/MALT1/ADAM8/HDAC4/SOCS1/RIPK2/BTN2A2/ADA/PTPN6/GPR18/ZAP70/CR1/PLCG2/CLEC4E/ERBB2/TCF7/BAK1/RHOH/TBX21/LILRB4/CD27/CD40LG/NCKAP1L/PIK3CD/SOD1/MS4A1/CD86/CD83/CD19/LEF1/TOX/FZD7/DOCK2/VAV1/LEP/ZFP36L1/IFNG/FLT3/PNP/PTGER4/SYK/CD80/SPI1/BTK/IL6/TPD52/PTPN22/INPP5D/IL18/IKZF1/MERTK/ZFP36L2/SPINK5/IL2RA/TP53/IFNA1/CR2/NLRP3	99
BP	GO:0032943	mononuclear cell proliferation	84/2112	274/18670	2.923e-18	1.063e-15	7.682e-16	CCL5/PLA2G2D/XCL1/CD3E/PTPRC/CTLA4/CCR2/BMP4/IRF1/IGF1/CORO1A/IDO1/TNFRSF1B/DLG5/LILRB2/RAC2/PRKCQ/GPR183/PSMB10/CCL19/PURA/IL15/IL7R/ELF4/SASH3/CD74/HLA-G/LGALS9/MALT1/CD40/TNFRSF14/TWSG1/RIPK2/TFRC/BTN2A2/HLA-E/ADA/PTPN6/TAC1/ZAP70/HLA-DPB1/ERBB2/PDCD1LG2/CD40LG/NCKAP1L/MS4A1/CD86/CD6/CD19/LEF1/HLA-DMB/DOCK2/LEP/IL6ST/MNDA/FLT3/PNP/SYK/CD80/BTN3A1/ICOSLG/BTK/TNFRSF4/IL6/PTPN22/CD38/INPP5D/HLA-DPA1/CD180/CD320/LST1/HELLS/IL18/LYN/IGFBP2/CD81/LRRC32/IL2RA/TP53/IFNA1/VAV3/IL1B/CR2/LILRB1	84
BP	GO:0071346	cellular response to interferon-gamma	63/2112	180/18670	3.836e-17	1.318e-14	9.521e-15	CCL5/XCL1/GBP1/IRF1/IRF9/HLA-F/HLA-A/GBP2/STAT1/CCL19/HLA-C/IRF8/CCL13/OAS2/TLR2/IRF4/PTPN2/OAS1/HLA-G/ICAM1/LGALS9/IRF7/JAK2/NMI/SOCS1/IRF2/HLA-E/OASL/HLA-DRA/HLA-DPB1/CCL21/HLA-B/WAS/TXK/FCGR1B/CCL18/CASP1/RAB20/TRIM21/KIF16B/IFNG/HLA-DQB2/STXBP2/CCL7/HSP90AB1/MYO1C/STX4/OAS3/STXBP1/TRIM22/HLA-DPA1/TRIM38/NR1H3/TRIM26/HCK/CCL17/ACTR3/TP53/CCL2/CCL23/GSN/ACTR2/PML	63
BP	GO:0030217	T cell differentiation	75/2112	240/18670	5.835e-17	1.899e-14	1.372e-14	ITK/CD3D/RELB/PLA2G2D/LCK/CD3E/PTPRC/CTLA4/CD2/CCR2/BMP4/BCL11B/IRF1/RUNX3/SEMA4A/RASGRP1/CD8A/LILRB2/GPR183/CCL19/ZBTB16/IL15/IL7R/BATF/GLI3/CCR7/SASH3/IRF4/CD74/PTPN2/TCIRG1/CD3G/IL4R/HLA-G/LGALS9/MALT1/ADAM8/SOCS1/RIPK2/BTN2A2/ADA/GPR18/ZAP70/CR1/CLEC4E/ERBB2/TCF7/RHOH/TBX21/LILRB4/CD27/NCKAP1L/PIK3CD/SOD1/CD86/CD83/LEF1/FZD7/DOCK2/VAV1/LEP/ZFP36L1/IFNG/PNP/PTGER4/SYK/CD80/IL6/PTPN22/IL18/ZFP36L2/SPINK5/IL2RA/TP53/NLRP3	75
BP	GO:0050670	regulation of lymphocyte proliferation	68/2112	208/18670	1.258e-16	3.716e-14	2.685e-14	CCL5/PLA2G2D/XCL1/CD3E/PTPRC/CTLA4/CCR2/BMP4/IRF1/IGF1/CORO1A/IDO1/TNFRSF1B/DLG5/LILRB2/RAC2/PRKCQ/GPR183/CCL19/IL15/SASH3/CD74/HLA-G/LGALS9/CD40/TNFRSF14/TWSG1/RIPK2/TFRC/BTN2A2/HLA-E/ADA/PTPN6/TAC1/ZAP70/HLA-DPB1/ERBB2/PDCD1LG2/CD40LG/NCKAP1L/CD86/CD6/HLA-DMB/LEP/IL6ST/MNDA/PNP/SYK/CD80/ICOSLG/BTK/TNFRSF4/IL6/PTPN22/CD38/INPP5D/HLA-DPA1/CD320/LST1/IL18/LYN/IGFBP2/CD81/LRRC32/IL2RA/VAV3/IL1B/LILRB1	68
BP	GO:0046631	alpha-beta T cell activation	53/2112	138/18670	1.262e-16	3.716e-14	2.685e-14	ITK/RELB/PLA2G2D/XCL1/CD3E/PTPRC/CCR2/BCL11B/IRF1/RUNX3/SEMA4A/PRKCQ/GPR183/CCL19/ZBTB16/IL15/ELF4/BATF/GLI3/SASH3/IRF4/TCIRG1/IL4R/LGALS9/MALT1/TNFRSF14/SOCS1/TWSG1/RIPK2/HLA-E/ADA/GPR18/ZAP70/CD160/TCF7/TBX21/NCKAP1L/CD86/CD83/LEF1/DOCK2/IFNG/CLEC4A/PNP/PTGER4/SYK/CD80/HFE/IL6/IL18/CD81/LILRB1/NLRP3	53
BP	GO:0032944	regulation of mononuclear cell proliferation	68/2112	209/18670	1.662e-16	4.67e-14	3.374e-14	CCL5/PLA2G2D/XCL1/CD3E/PTPRC/CTLA4/CCR2/BMP4/IRF1/IGF1/CORO1A/IDO1/TNFRSF1B/DLG5/LILRB2/RAC2/PRKCQ/GPR183/CCL19/IL15/SASH3/CD74/HLA-G/LGALS9/CD40/TNFRSF14/TWSG1/RIPK2/TFRC/BTN2A2/HLA-E/ADA/PTPN6/TAC1/ZAP70/HLA-DPB1/ERBB2/PDCD1LG2/CD40LG/NCKAP1L/CD86/CD6/HLA-DMB/LEP/IL6ST/MNDA/PNP/SYK/CD80/ICOSLG/BTK/TNFRSF4/IL6/PTPN22/CD38/INPP5D/HLA-DPA1/CD320/LST1/IL18/LYN/IGFBP2/CD81/LRRC32/IL2RA/VAV3/IL1B/LILRB1	68
BP	GO:0070663	regulation of leukocyte proliferation	70/2112	222/18670	3.796e-16	1.02e-13	7.372e-14	CCL5/PLA2G2D/KITLG/XCL1/CD3E/PTPRC/CTLA4/TNFAIP3/CCR2/BMP4/IRF1/IGF1/CORO1A/IDO1/TNFRSF1B/DLG5/LILRB2/RAC2/PRKCQ/GPR183/CCL19/IL15/SASH3/CD74/HLA-G/LGALS9/CD40/TNFRSF14/TWSG1/RIPK2/TFRC/BTN2A2/HLA-E/ADA/PTPN6/TAC1/ZAP70/HLA-DPB1/ERBB2/PDCD1LG2/CD40LG/NCKAP1L/CD86/CD6/HLA-DMB/LEP/IL6ST/MNDA/PNP/SYK/CD80/ICOSLG/BTK/TNFRSF4/IL6/PTPN22/CD38/INPP5D/HLA-DPA1/CD320/LST1/IL18/LYN/IGFBP2/CD81/LRRC32/IL2RA/VAV3/IL1B/LILRB1	70
BP	GO:0034341	response to interferon-gamma	65/2112	199/18670	6.216e-16	1.601e-13	1.157e-13	CCL5/XCL1/GBP1/IRF1/IRF9/GCH1/HLA-F/HLA-A/GBP2/STAT1/CCL19/HLA-C/KYNU/IRF8/CCL13/OAS2/TLR2/IRF4/PTPN2/OAS1/HLA-G/ICAM1/LGALS9/IRF7/JAK2/NMI/SOCS1/IRF2/HLA-E/OASL/HLA-DRA/HLA-DPB1/CCL21/HLA-B/WAS/TXK/FCGR1B/CCL18/CASP1/RAB20/TRIM21/KIF16B/IFNG/HLA-DQB2/STXBP2/CCL7/HSP90AB1/MYO1C/STX4/OAS3/STXBP1/TRIM22/HLA-DPA1/TRIM38/NR1H3/TRIM26/HCK/CCL17/ACTR3/TP53/CCL2/CCL23/GSN/ACTR2/PML	65
BP	GO:0060326	cell chemotaxis	85/2112	304/18670	8.792e-16	2.174e-13	1.571e-13	CCL5/CXCL13/SLAMF8/CXCL9/CCR5/XCL1/CCR2/S100A9/CORO1A/BIN2/RAC2/FGF18/CXCR4/PRKCQ/GPR183/CCL19/CCL13/CCR7/LPAR1/JAM3/CD74/ITGB2/LGALS9/ACKR3/ADAM8/CXCL1/DYSF/PDGFD/PRKD2/SCG2/GPSM3/CXCL10/HBEGF/FGF2/GPR18/THBS4/CXCL8/CCL21/HGF/CCR1/CX3CR1/CXCR6/EPHB1/CAMK1D/PTN/NCKAP1L/PIK3CD/PARVA/CCL18/LEF1/VAV1/HRH1/NOTCH1/CXCL3/NBL1/IL16/RHOG/AGTR1/CXCL11/CCL7/SLC12A2/SYK/EDNRB/HSPB1/IL6/CXCL2/CCR8/CXCL5/CXCL6/FPR2/ADAM10/VEGFB/IL1RN/PRKD1/MTUS1/LYN/KDR/CCL17/S1PR1/CCL2/CCRL2/CCL23/PLA2G7/VAV3/IL1B	85
BP	GO:0060333	interferon-gamma-mediated signaling pathway	40/2112	91/18670	3.057e-15	7.271e-13	5.253e-13	GBP1/IRF1/IRF9/HLA-F/HLA-A/GBP2/STAT1/HLA-C/IRF8/OAS2/IRF4/PTPN2/OAS1/HLA-G/ICAM1/IRF7/JAK2/NMI/SOCS1/IRF2/HLA-E/OASL/HLA-DRA/HLA-DPB1/HLA-B/TXK/FCGR1B/TRIM21/IFNG/HLA-DQB2/HSP90AB1/OAS3/TRIM22/HLA-DPA1/TRIM38/NR1H3/TRIM26/HCK/TP53/PML	40
BP	GO:0001819	positive regulation of cytokine production	111/2112	464/18670	7.222e-15	1.654e-12	1.195e-12	AIM2/XCL1/PIK3R1/CD3E/PTPRC/CD2/CCR2/IRF1/IL27RA/RASGRP1/BIRC3/CLU/TLR8/IDO1/HLA-F/LILRB2/STAT1/ZBTB20/PRKCQ/FCN1/CCL19/IL15/MYD88/IRF8/CCR7/NFKB2/SASH3/TLR2/IRF4/CD200/CD74/SULF1/LTB/IL4R/HLA-G/LGALS9/NOD2/IRF7/MALT1/ADAM8/JAK2/CD36/IFIH1/CD40/PRKD2/HTR2B/TNFRSF14/GPSM3/RIPK2/FGR/CRTAM/HLA-E/TSPAN6/CREBBP/SPHK1/CLEC7A/HLA-DPB1/PLCG2/CD160/CLEC4E/AKAP12/HGF/TXK/CD226/CD40LG/LUM/TLR5/SOD1/MAPK13/CADM1/DDX58/NFKB1/CD86/CASP1/CD83/CD6/SMAD3/PTPN11/LEP/IL6ST/DDX60/MNDA/IFNG/ARNT/PTGER4/FAM49B/DDX1/ADIPOQ/SYK/CD80/POLR2L/HSPB1/MAPKAPK2/IL6/PTPN22/HLA-DPA1/DDIT3/FERMT1/CYBA/IL18/IL1RN/NOD1/PANX1/CD81/IL1R1/SPTBN1/TLR6/IL1B/MMP12/LILRB1/NLRP3	111
BP	GO:0042098	T cell proliferation	60/2112	184/18670	8.891e-15	1.963e-12	1.418e-12	CCL5/PLA2G2D/XCL1/CD3E/PTPRC/CTLA4/CCR2/BMP4/IRF1/IGF1/CORO1A/IDO1/TNFRSF1B/DLG5/LILRB2/RAC2/PRKCQ/PSMB10/CCL19/IL15/ELF4/SASH3/HLA-G/LGALS9/MALT1/TNFRSF14/TWSG1/RIPK2/TFRC/BTN2A2/HLA-E/PTPN6/ZAP70/HLA-DPB1/ERBB2/PDCD1LG2/CD40LG/NCKAP1L/CD86/CD6/HLA-DMB/DOCK2/LEP/IL6ST/PNP/SYK/CD80/BTN3A1/ICOSLG/TNFRSF4/IL6/HLA-DPA1/IL18/IGFBP2/CD81/LRRC32/IL2RA/TP53/IL1B/LILRB1	60
BP	GO:0042129	regulation of T cell proliferation	53/2112	156/18670	4.901e-14	1.045e-11	7.549e-12	CCL5/PLA2G2D/XCL1/CD3E/PTPRC/CTLA4/CCR2/BMP4/IRF1/IGF1/CORO1A/IDO1/TNFRSF1B/DLG5/LILRB2/RAC2/PRKCQ/CCL19/IL15/SASH3/HLA-G/LGALS9/TNFRSF14/TWSG1/RIPK2/TFRC/BTN2A2/HLA-E/PTPN6/ZAP70/HLA-DPB1/ERBB2/PDCD1LG2/CD40LG/NCKAP1L/CD86/CD6/HLA-DMB/LEP/IL6ST/PNP/SYK/CD80/ICOSLG/IL6/HLA-DPA1/IL18/IGFBP2/CD81/LRRC32/IL2RA/IL1B/LILRB1	53
BP	GO:0045619	regulation of lymphocyte differentiation	55/2112	169/18670	1.268e-13	2.613e-11	1.888e-11	SLAMF8/SFRP1/PTPRC/CTLA4/CD2/CCR2/BMP4/IRF1/RUNX3/RASGRP1/LILRB2/CCL19/ZBTB16/IL15/IL7R/GLI3/INHBA/SASH3/IRF4/CD74/AXL/PTPN2/IL4R/HLA-G/LGALS9/MALT1/ADAM8/SOCS1/RIPK2/BTN2A2/ADA/PTPN6/ZAP70/CR1/ERBB2/TBX21/LILRB4/CD27/NCKAP1L/SOD1/CD86/CD83/TOX/ZFP36L1/IFNG/PNP/SYK/CD80/BTK/INPP5D/IL18/ZFP36L2/SPINK5/IL2RA/NLRP3	55
BP	GO:0070665	positive regulation of leukocyte proliferation	48/2112	139/18670	3.804e-13	7.588e-11	5.482e-11	CCL5/KITLG/XCL1/CD3E/PTPRC/CCR2/IGF1/CORO1A/LILRB2/PRKCQ/GPR183/CCL19/IL15/SASH3/CD74/LGALS9/CD40/RIPK2/TFRC/HLA-E/ADA/TAC1/ZAP70/HLA-DPB1/PDCD1LG2/CD40LG/NCKAP1L/CD86/CD6/HLA-DMB/LEP/IL6ST/PNP/SYK/CD80/ICOSLG/TNFRSF4/IL6/CD38/HLA-DPA1/CD320/IL18/LYN/IGFBP2/CD81/IL2RA/VAV3/IL1B	48
BP	GO:0050671	positive regulation of lymphocyte proliferation	46/2112	130/18670	4.287e-13	8.283e-11	5.985e-11	CCL5/XCL1/CD3E/PTPRC/CCR2/IGF1/CORO1A/LILRB2/PRKCQ/GPR183/CCL19/IL15/SASH3/CD74/LGALS9/CD40/RIPK2/TFRC/HLA-E/ADA/TAC1/ZAP70/HLA-DPB1/PDCD1LG2/CD40LG/NCKAP1L/CD86/CD6/HLA-DMB/LEP/IL6ST/PNP/SYK/CD80/ICOSLG/TNFRSF4/IL6/CD38/HLA-DPA1/CD320/IL18/IGFBP2/CD81/IL2RA/VAV3/IL1B	46
BP	GO:0050900	leukocyte migration	112/2112	499/18670	5.305e-13	9.939e-11	7.181e-11	CCL5/CXCL13/SLAMF8/CXCL9/KITLG/CCR5/XCL1/LCK/PIK3R1/CD2/CCR2/STK10/S100A9/IL27RA/CORO1A/CD48/ITGB7/RAC2/CXCR4/GPR183/CCL19/ITGA4/MMP1/CCL13/CCR7/SIRPG/JAM3/CD200/ANGPT1/CD74/ITGB2/ICAM1/LGALS9/SELL/ADAM8/CXCL1/DYSF/PDGFD/WASL/TNFRSF14/SCG2/GYPC/GPSM3/CXCL10/ADA/PTPN6/PROS1/GPR18/THBS4/ITGAL/ZAP70/CXCL8/IGHM/SELE/CCL21/CCR1/TBX21/GLG1/CX3CR1/CAMK1D/PTN/NCKAP1L/PIK3CD/CCL18/SLC7A5/ATP1B1/CEACAM5/PTPN11/VAV1/HRH1/CD9/CXCL3/LEP/NBL1/IL16/IGLC1/PECAM1/CXCL11/IGLV1-44/PIK3CA/PTGER4/CCL7/SLC12A2/SYK/EDNRB/ITGAX/IL6/FER/INPP5D/SELPLG/CXCL2/CXCL5/CXCL6/FPR2/ADAM10/VEGFB/IL1RN/MTUS1/LYN/HCK/CD81/MERTK/WDR1/CCL17/S1PR1/ITGAV/CCL2/CCL23/IL1R1/PLA2G7/VAV3/IL1B	112
BP	GO:0032946	positive regulation of mononuclear cell proliferation	46/2112	131/18670	5.891e-13	1.071e-10	7.74e-11	CCL5/XCL1/CD3E/PTPRC/CCR2/IGF1/CORO1A/LILRB2/PRKCQ/GPR183/CCL19/IL15/SASH3/CD74/LGALS9/CD40/RIPK2/TFRC/HLA-E/ADA/TAC1/ZAP70/HLA-DPB1/PDCD1LG2/CD40LG/NCKAP1L/CD86/CD6/HLA-DMB/LEP/IL6ST/PNP/SYK/CD80/ICOSLG/TNFRSF4/IL6/CD38/HLA-DPA1/CD320/IL18/IGFBP2/CD81/IL2RA/VAV3/IL1B	46
BP	GO:0032496	response to lipopolysaccharide	83/2112	330/18670	1.139e-12	2.012e-10	1.454e-10	CCL5/CXCL13/CSF2RB/CXCL9/CCR5/TNFAIP3/PENK/GCH1/IDO1/GNG12/TNFRSF1B/LILRB2/SLPI/IRF8/CCR7/NFKB2/TLR2/AXL/TIMP4/ICAM1/LGALS9/NOD2/MALT1/CXCL1/TNIP2/JAK2/CD36/CD96/HNRNPA0/CXCL10/RIPK2/DCN/TAC1/CXCL8/SELE/PLCG2/AKAP12/PDCD1LG2/CX3CR1/PCK1/NFKBIA/NFKB1/CD86/CASP1/CD6/NOTCH1/CXCL3/KMO/CXCL11/PTGFR/ALPL/PTGER4/CD80/IL10RA/EDNRB/GFI1/TNIP3/PAF1/MAPKAPK2/IL6/SGMS1/MAOB/PTPN22/FER/ADH5/CXCL2/CD180/NR1H3/CXCL5/LDOC1/CXCL6/IL18/TFPI/IL1RN/LYN/HCK/REN/ALAD/SBNO2/CCL2/IL1B/LILRB1/NLRP3	83
BP	GO:0048872	homeostasis of number of cells	68/2112	246/18670	1.21e-12	2.078e-10	1.502e-10	KITLG/AMPD3/TNFAIP3/CCR2/BMP4/CORO1A/RBFOX2/STAT1/GPR183/SOX9/IL7R/DOCK10/SH2B2/LAT/INHBA/CCR7/NFE2L1/SASH3/JAM3/CD74/AXL/PTPN2/CCNB2/HCLS1/TCIRG1/LGALS9/JAK2/GATA2/ADA/TGFBR3/BAK1/EZH2/NCKAP1L/PIK3CD/CDH2/SOD1/PMAIP1/PTPN11/MFHAS1/NOTCH1/P4HTM/ZFP36L1/ARNT/ADAR/FLT3/TRIM58/SPI1/AKT3/IL6/INPP5D/CXCL6/FOXO3/RB1/LYN/SH2B3/HIPK2/IKZF1/NLE1/MERTK/PRMT1/IL2RA/ISG15/PTBP3/UBAP2L/RPS14/HOXA5/THRA/TNFRSF17	68
BP	GO:0045621	positive regulation of lymphocyte differentiation	37/2112	94/18670	2.049e-12	3.423e-10	2.473e-10	PTPRC/RUNX3/RASGRP1/LILRB2/CCL19/ZBTB16/IL15/IL7R/GLI3/SASH3/CD74/AXL/IL4R/HLA-G/LGALS9/MALT1/ADAM8/SOCS1/RIPK2/BTN2A2/ADA/ZAP70/LILRB4/CD27/NCKAP1L/CD86/CD83/TOX/IFNG/PNP/SYK/CD80/BTK/INPP5D/IL18/IL2RA/NLRP3	37
BP	GO:1903708	positive regulation of hemopoiesis	56/2112	185/18670	2.204e-12	3.587e-10	2.592e-10	KITLG/PTPRC/RUNX3/RASGRP1/LILRB2/STAT1/CCL19/ZBTB16/IL15/IL7R/GLI3/FOXC1/INHBA/SASH3/CD74/AXL/HCLS1/IL4R/HLA-G/LGALS9/MALT1/ADAM8/SOCS1/GATA2/RIPK2/BTN2A2/EVI2B/ADA/ZAP70/CCR1/LILRB4/CD27/NCKAP1L/CD86/CD83/LEF1/TOX/CA2/ZFP36L1/IFNG/ARNT/PNP/SYK/CD80/TRIM58/BTK/INPP5D/TESC/FOXO3/RB1/IL18/PRMT1/IL2RA/ISG15/HOXA5/NLRP3	56
BP	GO:0002703	regulation of leukocyte mediated immunity	59/2112	201/18670	2.426e-12	3.846e-10	2.779e-10	XCL1/PTPRC/CCR2/IL27RA/RASGRP1/HLA-F/TNFRSF1B/HLA-A/RAC2/IL7R/HLA-C/SASH3/ITGB2/IL4R/HLA-G/LGALS9/NOD2/MALT1/CD96/CD40/MICB/GATA2/FGR/TFRC/CRTAM/HLA-E/PTPN6/SH2D1A/CR1/CD160/HLA-B/WAS/CD226/TBX21/IL13RA2/CADM1/DDX58/VAV1/LEP/STXBP2/FAM49B/DDX1/STX4/SYK/STXBP1/HFE/BTK/IL6/FER/CXCL6/IL18/GAB2/LYN/CD81/THOC1/IL1R1/IL1B/LILRB1/NLRP3	59
BP	GO:1902105	regulation of leukocyte differentiation	72/2112	272/18670	2.635e-12	4.073e-10	2.943e-10	SLAMF8/KITLG/PIK3R1/SFRP1/PTPRC/CTLA4/CD2/CCR2/BMP4/IRF1/RUNX3/RASGRP1/LILRB2/CCL19/ZBTB16/IL15/IL7R/GLI3/INHBA/SASH3/IRF4/CD74/AXL/PTPN2/HCLS1/IL4R/HLA-G/LGALS9/IRF7/MALT1/ADAM8/LILRB3/SOCS1/GATA2/RIPK2/BTN2A2/EVI2B/ADA/PTPN6/ZAP70/CR1/ERBB2/CCR1/TBX21/LILRB4/CD27/NCKAP1L/SOD1/CD86/CD83/LEF1/TOX/CA2/ZFP36L1/IFNG/PNP/ADIPOQ/SYK/CD80/BTK/INPP5D/TESC/RB1/IL18/LYN/FSTL3/ZFP36L2/SPINK5/TOB2/IL2RA/LILRB1/NLRP3	72
BP	GO:0046635	positive regulation of alpha-beta T cell activation	29/2112	62/18670	2.855e-12	4.198e-10	3.033e-10	XCL1/CD3E/PTPRC/CCR2/RUNX3/PRKCQ/CCL19/ZBTB16/GLI3/SASH3/IL4R/LGALS9/MALT1/SOCS1/RIPK2/HLA-E/ADA/ZAP70/CD160/NCKAP1L/CD86/CD83/IFNG/PNP/SYK/CD80/IL18/CD81/NLRP3	29
BP	GO:0042102	positive regulation of T cell proliferation	37/2112	95/18670	2.993e-12	4.198e-10	3.033e-10	CCL5/XCL1/CD3E/PTPRC/CCR2/IGF1/CORO1A/LILRB2/PRKCQ/CCL19/IL15/SASH3/LGALS9/RIPK2/TFRC/HLA-E/ZAP70/HLA-DPB1/PDCD1LG2/CD40LG/NCKAP1L/CD86/CD6/HLA-DMB/LEP/IL6ST/PNP/SYK/CD80/ICOSLG/IL6/HLA-DPA1/IL18/IGFBP2/CD81/IL2RA/IL1B	37
BP	GO:0060337	type I interferon signaling pathway	37/2112	95/18670	2.993e-12	4.198e-10	3.033e-10	PSMB8/IRF1/IRF9/HLA-F/HLA-A/GBP2/STAT1/MYD88/HLA-C/IRF8/OAS2/IRF4/PTPN2/MX2/OAS1/HLA-G/IRF7/XAF1/IRF2/HLA-E/IFI35/PTPN6/ISG20/IFI27/OASL/HLA-B/PTPN11/IFIT3/ADAR/HSP90AB1/OAS3/IFIT2/MX1/IFNA1/TYK2/ISG15/MMP12	37
BP	GO:0071357	cellular response to type I interferon	37/2112	95/18670	2.993e-12	4.198e-10	3.033e-10	PSMB8/IRF1/IRF9/HLA-F/HLA-A/GBP2/STAT1/MYD88/HLA-C/IRF8/OAS2/IRF4/PTPN2/MX2/OAS1/HLA-G/IRF7/XAF1/IRF2/HLA-E/IFI35/PTPN6/ISG20/IFI27/OASL/HLA-B/PTPN11/IFIT3/ADAR/HSP90AB1/OAS3/IFIT2/MX1/IFNA1/TYK2/ISG15/MMP12	37
BP	GO:0050852	T cell receptor signaling pathway	59/2112	202/18670	3.055e-12	4.198e-10	3.033e-10	ITK/CD3D/PSMB9/TRAC/TRBC1/LCK/PIK3R1/CD3E/PTPRC/CTLA4/GBP1/PSMB8/PVRIG/CSK/CD247/RFTN1/PRKCQ/PSMB10/TRAT1/LAT/CCR7/SKP1/PTPN2/LCP2/CD3G/MALT1/PRKD2/PSME1/RIPK2/BTN2A2/ADA/PTPN6/ZAP70/HLA-DRA/HLA-DPB1/PLCG2/CD160/THEMIS2/WAS/TXK/CD226/LILRB4/PIK3CD/SKAP1/NFKB1/BTN3A3/HLA-DQB2/PIK3CA/PAK1/TEC/BTN3A1/IKBKG/ICOSLG/BTK/PTPN22/INPP5D/HLA-DPA1/CD81/UBASH3A	59
BP	GO:0002683	negative regulation of immune system process	104/2112	463/18670	3.473e-12	4.669e-10	3.373e-10	SLAMF8/PLA2G2D/KITLG/XCL1/PIK3R1/SFRP1/PTPRC/CTLA4/TNFAIP3/CCR2/BMP4/GBP1/PVRIG/IRF1/IL27RA/RUNX3/LPXN/IDO1/HLA-F/DLG5/LILRB2/CST7/SOX9/ZBTB16/IL7R/GLI3/INHBA/MEIS1/IRF4/CD200/ANGPT1/CD74/AXL/PTPN2/HTRA1/IL4R/HLA-G/LGALS9/LILRB3/SAMSN1/NMI/CD96/MICB/WASL/TNFRSF14/SOCS1/TRAFD1/TWSG1/GATA2/MEIS2/BTN2A2/HLA-E/ADA/TSPAN6/PTPN6/GPR18/GPR171/CR1/CD160/CCL21/ERBB2/TBX21/PDCD1LG2/IL13RA2/LILRB4/NFKBIA/PTPRS/CD86/MFHAS1/NOTCH1/NBL1/ZFP36L1/MNDA/TAPBPL/SOCS6/ADAR/PTGER4/ADIPOQ/CD80/HFE/TGFB3/PAF1/BTK/PTPN22/FER/INPP5D/TRIM38/LST1/NR1H3/LYN/FSTL3/MERTK/SPINK5/THOC1/PRMT1/LRRC32/TOB2/UBASH3A/IL2RA/CCL2/TLR6/MMP12/HOXA5/LILRB1	104
BP	GO:0002237	response to molecule of bacterial origin	84/2112	343/18670	3.853e-12	5.069e-10	3.662e-10	CCL5/CXCL13/CSF2RB/CXCL9/CCR5/TNFAIP3/PENK/GCH1/IDO1/GNG12/TNFRSF1B/LILRB2/SLPI/IRF8/CCR7/NFKB2/TLR2/AXL/TIMP4/ICAM1/LGALS9/NOD2/MALT1/CXCL1/TNIP2/JAK2/CD36/CD96/HNRNPA0/CXCL10/RIPK2/DCN/TAC1/CXCL8/SELE/PLCG2/AKAP12/PDCD1LG2/CX3CR1/PCK1/NFKBIA/NFKB1/CD86/CASP1/CD6/NOTCH1/CXCL3/KMO/CXCL11/PTGFR/ALPL/PTGER4/CD80/IL10RA/EDNRB/GFI1/TNIP3/PAF1/MAPKAPK2/IL6/SGMS1/MAOB/PTPN22/FER/ADH5/CXCL2/CD180/NR1H3/CXCL5/LDOC1/CXCL6/IL18/TFPI/IL1RN/LYN/HCK/REN/ALAD/SBNO2/CCL2/TLR6/IL1B/LILRB1/NLRP3	84
BP	GO:0002699	positive regulation of immune effector process	61/2112	216/18670	6.45e-12	8.309e-10	6.003e-10	XCL1/PTPRC/CCR2/RASGRP1/HLA-F/HLA-A/RAC2/CCL19/HLA-C/SASH3/CD74/ITGB2/IL4R/HLA-G/LGALS9/NOD2/MALT1/CD36/CD40/MICB/TNFRSF14/GATA2/RIPK2/FGR/TFRC/CRTAM/HLA-E/SH2D1A/CD160/HLA-B/CD226/TBX21/IL13RA2/CADM1/DDX58/CD86/HLA-DMB/VAV1/RBP4/DDX60/IFNG/STXBP2/FAM49B/DDX1/STX4/SYK/CD80/STXBP1/BTK/TNFRSF4/IL6/FER/IL18/GAB2/LYN/CD81/IL1R1/IL1B/LILRB1/C6/NLRP3	61
BP	GO:0046634	regulation of alpha-beta T cell activation	36/2112	93/18670	7.26e-12	9.162e-10	6.619e-10	XCL1/CD3E/PTPRC/CCR2/IRF1/RUNX3/PRKCQ/CCL19/ZBTB16/GLI3/SASH3/IRF4/IL4R/LGALS9/MALT1/TNFRSF14/SOCS1/TWSG1/RIPK2/HLA-E/ADA/ZAP70/CD160/TBX21/NCKAP1L/CD86/CD83/IFNG/PNP/SYK/CD80/HFE/IL18/CD81/LILRB1/NLRP3	36
BP	GO:0050920	regulation of chemotaxis	61/2112	217/18670	7.998e-12	9.891e-10	7.146e-10	CCL5/CXCL13/SLAMF8/XCL1/CCR2/SEMA4A/RAC2/FGF18/CXCR4/GPR183/CCL19/SEMA4D/SEMA3A/CCR7/LPAR1/JAM3/CD74/PTPN2/LGALS9/DYSF/PDGFD/PRKD2/SCG2/GPSM3/CXCL10/TUBB2B/FGF2/GPR18/THBS4/CXCL8/CCL21/CCR1/CAMK1D/PTN/NCKAP1L/RYK/SEMA3F/SMAD3/NOTCH1/NBL1/IL16/PPM1F/CCL7/STX4/HSPB1/IL6/MEGF8/SEMA4F/FPR2/SEMA3E/ADAM10/VEGFB/PRKD1/MTUS1/LYN/KDR/SEMA6B/S1PR1/CCL2/FEZF2/PLA2G7	61
BP	GO:0030595	leukocyte chemotaxis	62/2112	224/18670	1.117e-11	1.354e-09	9.785e-10	CCL5/CXCL13/SLAMF8/CXCL9/CCR5/XCL1/CCR2/S100A9/CORO1A/RAC2/CXCR4/GPR183/CCL19/CCL13/CCR7/JAM3/CD74/ITGB2/LGALS9/ADAM8/CXCL1/DYSF/SCG2/GPSM3/CXCL10/GPR18/THBS4/CXCL8/CCL21/CCR1/CAMK1D/PTN/NCKAP1L/PIK3CD/CCL18/VAV1/HRH1/CXCL3/NBL1/IL16/CXCL11/CCL7/SLC12A2/SYK/EDNRB/IL6/CXCL2/CXCL5/CXCL6/FPR2/ADAM10/VEGFB/IL1RN/MTUS1/LYN/CCL17/S1PR1/CCL2/CCL23/PLA2G7/VAV3/IL1B	62
BP	GO:0034340	response to type I interferon	37/2112	99/18670	1.278e-11	1.519e-09	1.098e-09	PSMB8/IRF1/IRF9/HLA-F/HLA-A/GBP2/STAT1/MYD88/HLA-C/IRF8/OAS2/IRF4/PTPN2/MX2/OAS1/HLA-G/IRF7/XAF1/IRF2/HLA-E/IFI35/PTPN6/ISG20/IFI27/OASL/HLA-B/PTPN11/IFIT3/ADAR/HSP90AB1/OAS3/IFIT2/MX1/IFNA1/TYK2/ISG15/MMP12	37
BP	GO:1990266	neutrophil migration	41/2112	118/18670	1.556e-11	1.815e-09	1.312e-09	CCL5/CXCL13/SLAMF8/CXCL9/XCL1/S100A9/RAC2/CCL19/CCL13/CCR7/JAM3/CD74/ITGB2/ADAM8/CXCL1/DYSF/CXCL10/THBS4/CXCL8/CCL21/CAMK1D/NCKAP1L/PIK3CD/CCL18/VAV1/CXCL3/PECAM1/CXCL11/CCL7/SYK/CXCL2/CXCL5/CXCL6/IL1RN/WDR1/CCL17/CCL2/CCL23/IL1R1/VAV3/IL1B	41
BP	GO:0097529	myeloid leukocyte migration	59/2112	210/18670	1.799e-11	2.06e-09	1.488e-09	CCL5/CXCL13/SLAMF8/CXCL9/XCL1/CCR2/S100A9/RAC2/CCL19/CCL13/CCR7/JAM3/CD200/CD74/ITGB2/ADAM8/CXCL1/DYSF/PDGFD/SCG2/CXCL10/THBS4/CXCL8/CCL21/CCR1/CX3CR1/CAMK1D/NCKAP1L/PIK3CD/CCL18/VAV1/HRH1/CD9/CXCL3/NBL1/PECAM1/CXCL11/PTGER4/CCL7/SYK/EDNRB/IL6/CXCL2/CXCL5/CXCL6/FPR2/VEGFB/IL1RN/MTUS1/LYN/CD81/WDR1/CCL17/CCL2/CCL23/IL1R1/PLA2G7/VAV3/IL1B	59
BP	GO:0002697	regulation of immune effector process	101/2112	458/18670	2.241e-11	2.486e-09	1.796e-09	SLAMF8/TRAF3/AIM2/XCL1/PTPRC/TNFAIP3/CCR2/IL27RA/RASGRP1/BIRC3/CLU/HLA-F/TNFRSF1B/HLA-A/RAC2/STAT1/CCL19/IL15/IL7R/HLA-C/SASH3/IRF4/ANGPT1/CD74/APOBEC3G/ITGB2/HTRA1/IL4R/HLA-G/LGALS9/NOD2/MALT1/CD36/CFP/CD96/CD40/MICB/TNFRSF14/GATA2/RIPK2/FGR/TFRC/CRTAM/HLA-E/TSPAN6/PTPN6/PROS1/SH2D1A/CR1/CD160/HLA-B/WAS/CD226/TBX21/IL13RA2/CD40LG/CADM1/DDX58/CD86/CD19/HERC5/HLA-DMB/VAV1/RBP4/LEP/DDX60/IFNG/IGLC1/IGLV1-44/C7/STXBP2/FAM49B/DDX1/STX4/SYK/CD80/STXBP1/HFE/TGFB3/BTK/TNFRSF4/IL6/FER/IGHG1/TRIM38/CXCL6/IL18/GAB2/CFB/LYN/CD81/SPINK5/THOC1/IL2RA/IL1R1/IL1B/CR2/MMP12/LILRB1/C6/NLRP3	101
BP	GO:0018212	peptidyl-tyrosine modification	86/2112	366/18670	2.252e-11	2.486e-09	1.796e-09	CCL5/ITK/KITLG/LCK/CD3E/SFRP1/PTPRC/EPHA3/CRLF1/IGF1/DDR2/CSK/IL15/SEMA4D/NTRK2/SH3BP5/PPP2CA/ANGPT1/FGF7/CD74/AXL/PTPN2/HCLS1/ITGB2/NEK1/ICAM1/JAK2/SAMSN1/CD36/PDGFD/CD40/TNFRSF14/SOCS1/RIPK2/FGR/EGFR/GPRC5A/HBEGF/MELK/PTPN6/THBS4/ZAP70/CSPG4/GHR/ERBB2/HGF/TXK/ZGPAT/EHD4/EPHB1/NOX4/RYK/EFEMP1/HTR2A/EFNA5/PTPN11/LEP/IL6ST/IFNG/PECAM1/FLT3/ADIPOQ/SYK/CD80/TEC/ACVR1/FRK/CTF1/BTK/TPST1/IL6/TTK/FER/IL18/LYN/SH2B3/KDR/SLA/HCK/CD81/MERTK/NCF1/ABI2/TP53/MVP/TYK2	86
BP	GO:0045580	regulation of T cell differentiation	45/2112	139/18670	2.562e-11	2.767e-09	1.999e-09	PTPRC/CTLA4/CD2/CCR2/BMP4/IRF1/RUNX3/RASGRP1/LILRB2/CCL19/ZBTB16/IL15/IL7R/GLI3/SASH3/IRF4/CD74/PTPN2/IL4R/HLA-G/LGALS9/MALT1/ADAM8/SOCS1/RIPK2/BTN2A2/ADA/ZAP70/CR1/ERBB2/TBX21/LILRB4/CD27/NCKAP1L/SOD1/CD86/CD83/IFNG/PNP/SYK/CD80/IL18/SPINK5/IL2RA/NLRP3	45
BP	GO:1902107	positive regulation of leukocyte differentiation	46/2112	144/18670	2.596e-11	2.767e-09	1.999e-09	KITLG/PTPRC/RUNX3/RASGRP1/LILRB2/CCL19/ZBTB16/IL15/IL7R/GLI3/SASH3/CD74/AXL/HCLS1/IL4R/HLA-G/LGALS9/MALT1/ADAM8/SOCS1/RIPK2/BTN2A2/EVI2B/ADA/ZAP70/CCR1/LILRB4/CD27/NCKAP1L/CD86/CD83/LEF1/TOX/CA2/ZFP36L1/IFNG/PNP/SYK/CD80/BTK/INPP5D/TESC/RB1/IL18/IL2RA/NLRP3	46
BP	GO:0009615	response to virus	79/2112	326/18670	2.953e-11	3.094e-09	2.236e-09	CCL5/TRAF3/AIM2/CXCL9/XCL1/PTPRC/TNFAIP3/GBP1/PRF1/IRF1/RTP4/IRF9/BIRC3/PENK/CLU/TLR8/STAT1/CXCR4/CCL19/IL15/SERINC3/OAS2/APOBEC3G/MX2/HTRA1/OAS1/LGALS9/IRF7/IFIH1/CD40/MICB/IRF2/CXCL10/APOBEC3B/FGR/TSPAN6/ISG20/IFI27/OASL/TBX21/FAM111A/DDX58/PMAIP1/HYAL1/HERC5/ZMYND11/GTF2F1/DDX60/IFIT3/IFNG/ADAR/DDX1/OAS3/FOSL1/IKBKG/HSPB1/TRIM22/IL6/IVNS1ABP/TRIM38/IFIT5/PLSCR1/CFL1/HMGA1/IFIT2/CCDC130/MX1/ZC3HAV1/IL2RA/BNIP3L/PIM2/IFNA1/ISG15/IL1B/MMP12/PML/LILRB1/DCLK1/NLRP3	79
BP	GO:0002429	immune response-activating cell surface receptor signaling pathway	103/2112	473/18670	3.101e-11	3.195e-09	2.309e-09	ITK/CD3D/PSMB9/RELB/TRAC/PLEKHA1/TRBC1/LCK/PIK3R1/CD3E/PTPRC/CTLA4/GBP1/PSMB8/PVRIG/LPXN/PRKCH/CSK/CD247/RFTN1/CLEC10A/PRKCQ/FCN1/PSMB10/SH2B2/TRAT1/LAT/CCR7/PRKCB/SKP1/PTPN2/LCP2/CD3G/MALT1/MICB/PRKD2/WASL/PSME1/RIPK2/FGR/BTN2A2/ADA/PTPN6/CREBBP/ZAP70/HLA-DRA/CR1/IGHM/IGLL5/HLA-DPB1/PLCG2/CD160/THEMIS2/WAS/CLEC4E/TXK/CD226/LILRB4/DOCK1/NCKAP1L/PIK3CD/SKAP1/NFKB1/ICAM3/MS4A1/CD19/BTN3A3/CYFIP2/VAV1/FPR1/PAX5/MNDA/CLEC4A/IGLC1/IGLV1-44/HLA-DQB2/PIK3CA/HSP90AB1/PAK1/MYO1C/SYK/TEC/BTN3A1/IKBKG/ICOSLG/BTK/PTPN22/CD38/IGHG1/INPP5D/HLA-DPA1/PLSCR1/FPR2/LYN/HCK/ARPC1A/CD81/WASF2/ACTR3/UBASH3A/VAV3/CR2/ACTR2	103
BP	GO:0018108	peptidyl-tyrosine phosphorylation	85/2112	363/18670	3.564e-11	3.612e-09	2.61e-09	CCL5/ITK/KITLG/LCK/CD3E/SFRP1/PTPRC/EPHA3/CRLF1/IGF1/DDR2/CSK/IL15/SEMA4D/NTRK2/SH3BP5/PPP2CA/ANGPT1/FGF7/CD74/AXL/PTPN2/HCLS1/ITGB2/NEK1/ICAM1/JAK2/SAMSN1/CD36/PDGFD/CD40/TNFRSF14/SOCS1/RIPK2/FGR/EGFR/GPRC5A/HBEGF/MELK/PTPN6/THBS4/ZAP70/CSPG4/GHR/ERBB2/HGF/TXK/ZGPAT/EHD4/EPHB1/NOX4/RYK/EFEMP1/HTR2A/EFNA5/PTPN11/LEP/IL6ST/IFNG/PECAM1/FLT3/ADIPOQ/SYK/CD80/TEC/ACVR1/FRK/CTF1/BTK/IL6/TTK/FER/IL18/LYN/SH2B3/KDR/SLA/HCK/CD81/MERTK/NCF1/ABI2/TP53/MVP/TYK2	85
BP	GO:0050851	antigen receptor-mediated signaling pathway	77/2112	316/18670	3.951e-11	3.94e-09	2.847e-09	ITK/CD3D/PSMB9/TRAC/PLEKHA1/TRBC1/LCK/PIK3R1/CD3E/PTPRC/CTLA4/GBP1/PSMB8/PVRIG/LPXN/PRKCH/CSK/CD247/RFTN1/PRKCQ/PSMB10/SH2B2/TRAT1/LAT/CCR7/PRKCB/SKP1/PTPN2/LCP2/CD3G/MALT1/PRKD2/PSME1/RIPK2/BTN2A2/ADA/PTPN6/ZAP70/HLA-DRA/IGHM/IGLL5/HLA-DPB1/PLCG2/CD160/THEMIS2/WAS/TXK/CD226/LILRB4/NCKAP1L/PIK3CD/SKAP1/NFKB1/MS4A1/CD19/BTN3A3/PAX5/MNDA/IGLC1/HLA-DQB2/PIK3CA/PAK1/SYK/TEC/BTN3A1/IKBKG/ICOSLG/BTK/PTPN22/CD38/IGHG1/INPP5D/HLA-DPA1/LYN/CD81/UBASH3A/VAV3	77
BP	GO:0031294	lymphocyte costimulation	26/2112	57/18670	7.73e-11	7.587e-09	5.482e-09	LCK/PIK3R1/CD3E/CTLA4/CSK/CCL19/CCR7/CD5/TNFRSF14/MAP3K8/PTPN6/CD160/CCL21/PDCD1LG2/CD40LG/CD86/ICOS/PTPN11/VAV1/PIK3CA/PAK1/CD80/ICOSLG/CD320/LYN/CD81	26
BP	GO:0050663	cytokine secretion	63/2112	240/18670	8.901e-11	8.59e-09	6.206e-09	AIM2/TNFAIP3/CD2/GBP1/IL27RA/RASGRP1/TLR8/TNFRSF1B/FCN1/CCL19/CCR7/TLR2/CD200/ANGPT1/LCP2/TCIRG1/IL4R/LGALS9/NOD2/DYSF/CD36/IFIH1/HTR2B/TNFRSF14/SOCS1/RIPK2/FGR/CRTAM/BTN2A2/SRGN/CD160/CLEC4E/AKAP12/S100A13/TLR5/CADM1/DDX58/CASP1/NOTCH1/LEP/IFNG/PNP/PTGER4/SYK/BTN3A1/SERPINB1/TNFRSF4/PTPN22/ANXA4/FERMT1/PPP1R11/LYN/PANX1/LRRC32/ITGAV/ISG15/SPTBN1/TLR6/IL1B/MMP12/PML/LILRB1/NLRP3	63
BP	GO:1903706	regulation of hemopoiesis	102/2112	475/18670	9.03e-11	8.59e-09	6.206e-09	SLAMF8/PSMB9/KITLG/PIK3R1/SFRP1/PTPRC/CTLA4/CD2/CCR2/BMP4/PSMB8/IRF1/RUNX3/RASGRP1/RBFOX2/LILRB2/STAT1/PRKCQ/PSMB10/CCL19/ZBTB16/IL15/IL7R/PIM1/GLI3/FOXC1/INHBA/MEIS1/PRKCB/SASH3/IRF4/CD74/AXL/PTPN2/HCLS1/IL4R/HLA-G/LGALS9/IRF7/MALT1/ADAM8/LILRB3/SOCS1/YAP1/GATA2/PSME1/RIPK2/MEIS2/BTN2A2/EVI2B/ADA/PTPN6/CREBBP/KMT2A/ZAP70/GPR171/CR1/ERBB2/CCR1/TBX21/LILRB4/CD27/NFKBIA/PTN/NCKAP1L/SOD1/CD86/CD83/LEF1/TOX/CA2/NOTCH1/P4HTM/ZFP36L1/IFNG/ARNT/PNP/ADIPOQ/SYK/CD80/TRIM58/SPI1/PAF1/BTK/INPP5D/TESC/FOXO3/MYL9/RB1/IL18/LYN/FSTL3/GP1BA/ZFP36L2/SPINK5/PRMT1/TOB2/IL2RA/ISG15/HOXA5/LILRB1/NLRP3	102
BP	GO:0002695	negative regulation of leukocyte activation	51/2112	175/18670	9.8e-11	9.181e-09	6.634e-09	PLA2G2D/XCL1/SFRP1/PTPRC/CTLA4/TNFAIP3/CCR2/BMP4/IRF1/RUNX3/IDO1/HLA-F/DLG5/LILRB2/CST7/GLI3/INHBA/CD200/CD74/AXL/PTPN2/IL4R/HLA-G/LGALS9/SAMSN1/TNFRSF14/SOCS1/TWSG1/BTN2A2/PTPN6/ERBB2/TBX21/PDCD1LG2/IL13RA2/CD86/MNDA/SOCS6/CD80/HFE/BTK/PTPN22/FER/INPP5D/LST1/NR1H3/LYN/MERTK/THOC1/LRRC32/IL2RA/LILRB1	51
BP	GO:0046632	alpha-beta T cell differentiation	36/2112	101/18670	1.165e-10	1.075e-08	7.767e-09	ITK/RELB/PLA2G2D/BCL11B/IRF1/RUNX3/SEMA4A/GPR183/CCL19/ZBTB16/BATF/GLI3/SASH3/IRF4/IL4R/LGALS9/MALT1/SOCS1/RIPK2/ADA/GPR18/ZAP70/TCF7/TBX21/NCKAP1L/CD86/CD83/LEF1/IFNG/PNP/PTGER4/SYK/CD80/IL6/IL18/NLRP3	36
BP	GO:0045582	positive regulation of T cell differentiation	32/2112	83/18670	1.191e-10	1.083e-08	7.827e-09	PTPRC/RUNX3/RASGRP1/LILRB2/CCL19/ZBTB16/IL7R/GLI3/SASH3/CD74/IL4R/HLA-G/LGALS9/MALT1/ADAM8/SOCS1/RIPK2/BTN2A2/ADA/ZAP70/LILRB4/CD27/NCKAP1L/CD86/CD83/IFNG/PNP/SYK/CD80/IL18/IL2RA/NLRP3	32
BP	GO:0045088	regulation of innate immune response	98/2112	452/18670	1.212e-10	1.086e-08	7.847e-09	CCL5/SLAMF8/TRAF3/AIM2/PSMB9/RELB/TNFAIP3/S100A9/PSMB8/IRF1/RASGRP1/BIRC3/TLR8/HLA-F/STAT1/RFTN1/CLEC10A/FCN1/PSMB10/MYD88/SKP1/TLR2/IRF4/PTPN2/ITGB2/HLA-G/LGALS9/NOD2/COCH/IRF7/MALT1/ADAM8/TNIP2/JAK2/CD36/NMI/IFIH1/CD96/MICB/SOCS1/CTSL/TRAFD1/PSME1/RIPK2/FGR/CRTAM/HLA-E/TSPAN6/PTPN6/CREBBP/CLEC7A/SH2D1A/CR1/PLCG2/CD160/CLEC4E/TXK/CD226/NFKBIA/TLR5/CADM1/DDX58/PTPRS/NFKB1/ICAM3/CTSB/PTPN11/VAV1/MFHAS1/UBE2D1/COLEC12/HEXIM1/LEP/DDX60/MNDA/IFNG/CLEC4A/ADAR/HSP90AB1/PAK1/SYK/GFI1/IKBKG/TNIP3/BTK/MAPKAPK2/PTPN22/PLSCR1/NR1H3/FPR2/CYBA/LYN/NOD1/HCK/RAB11FIP2/TLR6/MMP12/LILRB1	98
BP	GO:0042119	neutrophil activation	105/2112	498/18670	1.459e-10	1.289e-08	9.311e-09	CCL5/AMPD3/CPNE3/SERPINA1/PTPRC/STK10/S100A9/TMC6/METTL7A/BIN2/TNFRSF1B/LILRB2/GCA/SERPINA3/FCN1/IL15/SLPI/COTL1/TLR2/TCIRG1/HBB/ITGB2/LILRA3/LRMP/SELL/ADAM8/LILRB3/CXCL1/CTSC/CD36/CFP/LYZ/RHOF/TIMP2/PLAC8/ANXA3/PGRMC1/FGR/ATP8A1/HK3/CYB5R3/PTPN6/ALDOC/HSPA6/ITGAL/CXCL8/CR1/PLEKHO2/MAGT1/CD93/PLD1/NCKAP1L/GMFG/CFD/CD53/NFKB1/SLC2A3/CTSB/QPCT/RAB27A/DOCK2/VCP/FPR1/RHOG/MNDA/PECAM1/STXBP2/FUCA1/PNP/HSP90AB1/PRDX6/SYK/FABP5/FRK/ITGAX/TSPAN14/SERPINB1/C6orf120/APAF1/ANPEP/HP/GLA/CXCL6/FPR2/CYBA/IL18/ADAM10/MAN2B1/CAT/ALAD/GOLGA7/CANT1/MANBA/NBEAL2/ITGAV/MVP/SLC2A5/FCGR3B/IQGAP2/RAB14/GSN/PTX3/ACTR2/ALOX5/CTSH	105
BP	GO:0030099	myeloid cell differentiation	92/2112	416/18670	1.501e-10	1.307e-08	9.445e-09	RELB/KITLG/PIK3R1/SFRP1/LBR/BMP4/CDKN1C/RBFOX2/STAT1/PRKCQ/GPR183/FLI1/CCL19/ZBTB16/IL15/BATF/IRF8/INHBA/CCR7/MEIS1/PIR/NFE2L1/PRKCB/TLR2/IRF4/CD74/PTPN2/HCLS1/TCIRG1/CBFA2T3/IRF7/LILRB3/JAK2/GATA2/TFRC/MEIS2/EVI2B/SH3PXD2A/PTPN6/TGFBR3/CREBBP/KMT2A/GPR171/CCR1/LILRB4/NFKBIA/NCKAP1L/PIK3CD/LEF1/PTPN11/CA2/MFHAS1/GLO1/P4HTM/ZFP36L1/IFNG/ARNT/ADAR/ADIPOQ/PARP1/TRIM58/SPI1/PAF1/INPP5D/TESC/PIP4K2A/FOXO3/MYL9/RB1/GAB2/LYN/CEBPA/SH2B3/HIPK2/FSTL3/SNX10/IKZF1/CD81/WASF2/GP1BA/WDR1/PRMT1/TOB2/SBNO2/NBEAL2/ISG15/PTBP3/RPS14/HOXA5/PML/LILRB1/THRA	92
BP	GO:0097530	granulocyte migration	44/2112	141/18670	1.647e-10	1.415e-08	1.022e-08	CCL5/CXCL13/SLAMF8/CXCL9/XCL1/S100A9/RAC2/CCL19/CCL13/CCR7/JAM3/CD74/ITGB2/ADAM8/CXCL1/DYSF/SCG2/CXCL10/THBS4/CXCL8/CCL21/CAMK1D/NCKAP1L/PIK3CD/CCL18/VAV1/HRH1/CXCL3/PECAM1/CXCL11/PTGER4/CCL7/SYK/CXCL2/CXCL5/CXCL6/IL1RN/WDR1/CCL17/CCL2/CCL23/IL1R1/VAV3/IL1B	44
BP	GO:0030593	neutrophil chemotaxis	36/2112	104/18670	3.004e-10	2.545e-08	1.839e-08	CCL5/CXCL13/CXCL9/XCL1/S100A9/RAC2/CCL19/CCL13/CCR7/JAM3/CD74/ITGB2/CXCL1/DYSF/CXCL10/THBS4/CXCL8/CCL21/CAMK1D/NCKAP1L/PIK3CD/CCL18/VAV1/CXCL3/CXCL11/CCL7/SYK/CXCL2/CXCL5/CXCL6/IL1RN/CCL17/CCL2/CCL23/VAV3/IL1B	36
BP	GO:0032103	positive regulation of response to external stimulus	76/2112	323/18670	3.065e-10	2.561e-08	1.85e-08	CCL5/CXCL13/XCL1/CCR2/S100A9/IDO1/RAC2/FGF18/CXCR4/CCL19/IL15/MYD88/CCR7/LPAR1/TLR2/CD74/LGALS9/NOD2/ADAM8/DYSF/JAK2/CTSC/PDGFD/PRKD2/SCG2/GPSM3/CXCL10/RIPK2/TUBB2B/EGFR/HLA-E/FGF2/THBS4/CLEC7A/TAC1/CXCL8/CCL21/CCR1/SCARF1/NFKBIA/CAMK1D/PTN/NCKAP1L/MAPK13/CCL18/CD6/SMAD3/IL6ST/IL16/DDX60/AGTR1/PPM1F/PTGER4/CCL7/STX4/HSPB1/BTK/IL6/MEGF8/CD180/FPR2/CYBA/IL18/ADAM10/VEGFB/FABP4/PRKD1/NOD1/CEBPA/KDR/CD81/S1PR1/TGM2/PLA2G7/TLR6/IL1B	76
BP	GO:0031295	T cell costimulation	25/2112	56/18670	3.165e-10	2.609e-08	1.885e-08	LCK/PIK3R1/CD3E/CTLA4/CSK/CCL19/CCR7/CD5/TNFRSF14/MAP3K8/PTPN6/CD160/CCL21/PDCD1LG2/CD40LG/CD86/ICOS/PTPN11/VAV1/PIK3CA/PAK1/CD80/ICOSLG/LYN/CD81	25
BP	GO:0002819	regulation of adaptive immune response	47/2112	160/18670	3.928e-10	3.195e-08	2.309e-08	XCL1/PTPRC/TNFAIP3/CCR2/IRF1/IL27RA/CD48/HLA-F/TNFRSF1B/HLA-A/PRKCQ/CCL19/IL7R/HLA-C/SASH3/IL4R/HLA-G/IRF7/MALT1/SAMSN1/CD40/TNFRSF14/RIPK2/TFRC/HLA-E/ADA/PTPN6/CR1/CD160/HLA-B/WAS/CD226/TBX21/SKAP1/IL6ST/FAM49B/CD80/HFE/BTK/IL6/IL18/CD81/THOC1/IL1R1/IL1B/LILRB1/NLRP3	47
BP	GO:0019882	antigen processing and presentation	59/2112	226/18670	4.417e-10	3.547e-08	2.563e-08	PSMB9/RELB/TAP1/TAPBP/PSMB8/HLA-F/CD8A/LILRB2/HLA-A/RFTN1/PSMB10/CCL19/CTSF/TAP2/HLA-C/CCR7/CD74/HLA-G/ICAM1/NOD2/DYNC1LI2/CD36/CTSL/PSME1/ERAP2/HLA-E/KIF11/KIF15/HLA-DRA/KIF3B/HLA-DPB1/CCL21/HLA-B/SEC31A/WAS/FCGR1B/NCF4/KIF2C/KIF4A/DYNC1I1/HLA-DMA/HLA-DMB/RAB27A/RACGAP1/CLEC4A/TAPBPL/HLA-DQB2/DCTN6/IKBKG/HFE/HLA-DPA1/CAPZA1/OSBPL1A/CYBA/NOD1/NCF1/ITGAV/CTSH/KIF23	59
BP	GO:0050921	positive regulation of chemotaxis	42/2112	135/18670	4.736e-10	3.754e-08	2.713e-08	CCL5/CXCL13/XCL1/CCR2/RAC2/FGF18/CXCR4/CCL19/CCR7/LPAR1/CD74/LGALS9/DYSF/PDGFD/PRKD2/SCG2/GPSM3/CXCL10/TUBB2B/FGF2/THBS4/CXCL8/CCL21/CCR1/CAMK1D/PTN/NCKAP1L/SMAD3/IL16/PPM1F/CCL7/STX4/HSPB1/IL6/MEGF8/FPR2/ADAM10/VEGFB/PRKD1/KDR/S1PR1/PLA2G7	42
BP	GO:0006909	phagocytosis	83/2112	369/18670	5.018e-10	3.927e-08	2.837e-08	IL2RG/TRBC1/PIK3R1/PTPRC/SLAMF1/CORO1A/BIN2/CSK/IL15RA/CD247/ARHGAP25/IL2RB/FCN1/IL15/MYD88/IRF8/SIRPG/TLR2/AXL/ITGB2/CD3G/DYSF/CD36/WASL/ANXA3/GATA2/FGR/SPHK1/ITGAL/CLEC7A/GULP1/IGHM/IGLL5/PLCG2/WAS/CD93/NCF4/CAMK1D/DOCK1/NCKAP1L/SOD1/ICAM3/RAB20/CEACAM4/CYFIP2/RAB27A/DOCK2/VAV1/COLEC12/LEP/IFNG/IGLC1/PECAM1/IGLV1-44/PIK3CA/HSP90AB1/PAK1/MYO1C/ADIPOQ/ATG3/SYK/P2RY6/IGHG1/NR1H3/FPR2/CYBA/LYN/HCK/ARPC1A/WASF2/MERTK/TGM2/ACTR3/RAB11FIP2/ITGAV/CCL2/RAB14/GSN/VAV3/IL1B/PTX3/ARHGAP12/ACTR2	83
BP	GO:0050866	negative regulation of cell activation	54/2112	199/18670	5.236e-10	4.047e-08	2.924e-08	PLA2G2D/XCL1/SFRP1/PTPRC/CTLA4/TNFAIP3/CCR2/BMP4/IRF1/RUNX3/IDO1/HLA-F/DLG5/LILRB2/CST7/GLI3/INHBA/CD200/CD74/AXL/PTPN2/IL4R/HLA-G/LGALS9/SAMSN1/TNFRSF14/SOCS1/TWSG1/BTN2A2/PTPN6/ERBB2/TBX21/PDCD1LG2/IL13RA2/CD86/CD9/MNDA/SOCS6/CD80/HFE/BTK/PTPN22/FER/PRKG1/INPP5D/LST1/NR1H3/LYN/SH2B3/MERTK/THOC1/LRRC32/IL2RA/LILRB1	54
BP	GO:0007052	mitotic spindle organization	36/2112	106/18670	5.509e-10	4.205e-08	3.038e-08	TACC3/MAP4/NDC80/EML1/GOLGA2/PLK1/TPX2/BORA/KIF11/KIF3B/TPR/TACC1/MAP9/ZNF207/STAG2/KIF4A/ARHGEF10/PRC1/NEK2/PLK2/RACGAP1/VCP/SPC25/TACC2/CCNB1/MECP2/TTK/CHMP2B/AURKB/CDC20/TUBG2/AURKA/KIFC1/CHMP1B/STIL/KIF23	36
BP	GO:0051250	negative regulation of lymphocyte activation	44/2112	146/18670	5.753e-10	4.338e-08	3.134e-08	PLA2G2D/XCL1/SFRP1/CTLA4/TNFAIP3/BMP4/IRF1/RUNX3/IDO1/HLA-F/DLG5/LILRB2/GLI3/INHBA/CD74/AXL/PTPN2/IL4R/HLA-G/LGALS9/SAMSN1/TNFRSF14/SOCS1/TWSG1/BTN2A2/PTPN6/ERBB2/TBX21/PDCD1LG2/CD86/MNDA/SOCS6/CD80/HFE/BTK/PTPN22/INPP5D/LST1/LYN/MERTK/THOC1/LRRC32/IL2RA/LILRB1	44
BP	GO:0070098	chemokine-mediated signaling pathway	32/2112	88/18670	6.911e-10	5.148e-08	3.72e-08	CCL5/CXCL13/CXCL9/CCR5/XCL1/CCR2/CXCR4/CCL19/FOXC1/CCL13/CCR7/ACKR3/CXCL1/CXCL10/CXCL8/CCL21/CCR1/CX3CR1/CXCR6/CCL18/CXCL3/CXCL11/CCL7/CXCL2/CCR8/CXCL5/CXCL6/SH2B3/CCL17/CCL2/CCRL2/CCL23	32
BP	GO:0043491	protein kinase B signaling	66/2112	269/18670	7.157e-10	5.268e-08	3.806e-08	CCL5/KITLG/PLEKHA1/LCK/PIK3R1/IGFBP5/IGF1/BTC/RAC2/FGF18/CCL19/SOX9/NTRK2/TRAT1/AKR1C3/CCR7/ANGPT1/FGF7/AXL/HCLS1/ITGB1BP1/HLA-G/ADAM8/ITSN1/CD40/EGFR/BTN2A2/HBEGF/DAG1/FGF2/CCL21/ERBB2/TMEM100/HGF/MAGI2/TCF7L2/CX3CR1/NOX4/PIK3CD/RRAS/CD86/CD19/ICOS/PTPN11/VAV1/MFHAS1/KL/MYOC/LEP/ZFP36L1/RHOG/PIK3CA/HSP90AB1/PHLPP1/CD80/FGF9/PINK1/PIK3R3/RCN3/DDIT3/IL18/SH2B3/KDR/MERTK/CCL2/IL1B	66
BP	GO:0002446	neutrophil mediated immunity	103/2112	499/18670	7.607e-10	5.533e-08	3.998e-08	AMPD3/CPNE3/SERPINA1/PTPRC/STK10/S100A9/TMC6/METTL7A/BIN2/TNFRSF1B/LILRB2/GCA/SERPINA3/FCN1/SLPI/COTL1/TLR2/TCIRG1/HBB/ITGB2/LILRA3/LRMP/SELL/ADAM8/LILRB3/CXCL1/CTSC/CD36/CFP/LYZ/RHOF/TIMP2/PLAC8/ANXA3/PGRMC1/FGR/ATP8A1/HK3/CYB5R3/PTPN6/ALDOC/HSPA6/ITGAL/CR1/PLEKHO2/MAGT1/CD93/PLD1/NCKAP1L/GMFG/CFD/CD53/NFKB1/SLC2A3/CTSB/QPCT/RAB27A/DOCK2/VCP/FPR1/RHOG/MNDA/PECAM1/STXBP2/FUCA1/PNP/HSP90AB1/PRDX6/SYK/FABP5/FRK/ITGAX/TSPAN14/SERPINB1/C6orf120/APAF1/IL6/ANPEP/HP/GLA/CXCL6/FPR2/CYBA/ADAM10/MAN2B1/WDR1/CAT/ALAD/GOLGA7/CANT1/MANBA/NBEAL2/ITGAV/MVP/SLC2A5/FCGR3B/IQGAP2/RAB14/GSN/PTX3/ACTR2/ALOX5/CTSH	103
BP	GO:0071216	cellular response to biotic stimulus	60/2112	236/18670	9.696e-10	6.971e-08	5.037e-08	CCL5/CXCL13/CXCL9/CCR5/TNFAIP3/TNFRSF1B/LILRB2/IRF8/TLR2/AXL/ICAM1/NOD2/MALT1/CXCL1/TNIP2/CD36/CXCL10/RIPK2/CLEC7A/CXCL8/PDCD1LG2/CX3CR1/NFKBIA/NFKB1/CD86/CASP1/CD6/CXCL3/KMO/CXCL11/SYK/CD80/EDNRB/GFI1/TNIP3/PAF1/BTK/APAF1/IL6/SGMS1/PTPN22/CXCL2/CD180/DDIT3/NR1H3/CXCL5/LDOC1/CXCL6/IL18/TFPI/IL1RN/LYN/HCK/SBNO2/TP53/CCL2/TLR6/IL1B/LILRB1/NLRP3	60
BP	GO:0007162	negative regulation of cell adhesion	69/2112	289/18670	1.036e-09	7.36e-08	5.318e-08	ADAMDEC1/PLA2G2D/XCL1/PIK3R1/PTPRC/CTLA4/BMP4/GBP1/IRF1/RUNX3/LPXN/IDO1/DLG5/LILRB2/ARHGDIB/SIPA1/SEMA4D/GLI3/SPOCK1/ANGPT1/CD74/PTPN2/ITGB1BP1/IL4R/HLA-G/LGALS9/JAK2/TNFRSF14/SOCS1/TWSG1/BTN2A2/PTPN6/DLC1/CCL21/ERBB2/SPINT2/TBX21/PDCD1LG2/CD86/FZD4/ADAM22/EFNA5/PTPN11/FZD7/CORO2B/CD9/NOTCH1/MYOC/KANK1/SOCS6/PPM1F/ADIPOQ/CD80/HFE/PTPN22/PRKG1/AP1AR/FBLN1/SEMA3E/ADAM10/IL1RN/SH2B3/PDE3B/CD164/LRRC32/IL2RA/CASK/MMP12/LILRB1	69
BP	GO:0050708	regulation of protein secretion	98/2112	472/18670	1.425e-09	9.955e-08	7.193e-08	CCL5/AIM2/SFRP1/TNFAIP3/CD2/GBP1/IL27RA/IGF1/RASGRP1/TLR8/TNFRSF1B/MYH10/RHBDF2/FCN1/CCL19/SRI/OXCT1/PPP3CA/CCR7/ABCG1/TLR2/CD200/ANGPT1/TCIRG1/PAM/IL4R/LGALS9/NOD2/ADAM8/WLS/JAK2/IFIH1/CD40/HTR2B/TNFRSF14/SOCS1/RIPK2/FGR/CRTAM/EGFR/BTN2A2/HLA-E/SRGN/KLF7/TM7SF3/MPC2/IDH2/CD160/CLEC4E/AKAP12/TCF7L2/PER2/CD40LG/LRP5/TLR5/CADM1/RHBDF1/DDX58/CASP1/EFNA5/PTPN11/RBP4/ARNTL/SLC25A4/LEP/SSTR5/IFNG/OR51E2/PTGER4/STX4/SYK/TGFB3/SERPINB1/TNFRSF4/IL6/PTPN22/CD38/SYBU/ANXA4/NR1H3/ENSA/FERMT1/PPP1R11/SLC25A5/ANG/LYN/PANX1/HADH/LRRC32/SPTBN1/TLR6/IL1B/MMP12/PML/RAB11FIP1/LILRB1/GPR27/NLRP3	98
BP	GO:0043312	neutrophil degranulation	100/2112	485/18670	1.433e-09	9.955e-08	7.193e-08	AMPD3/CPNE3/SERPINA1/PTPRC/STK10/S100A9/TMC6/METTL7A/BIN2/TNFRSF1B/LILRB2/GCA/SERPINA3/FCN1/SLPI/COTL1/TLR2/TCIRG1/HBB/ITGB2/LILRA3/LRMP/SELL/ADAM8/LILRB3/CXCL1/CTSC/CD36/CFP/LYZ/RHOF/TIMP2/PLAC8/ANXA3/PGRMC1/FGR/ATP8A1/HK3/CYB5R3/PTPN6/ALDOC/HSPA6/ITGAL/CR1/PLEKHO2/MAGT1/CD93/PLD1/NCKAP1L/GMFG/CFD/CD53/NFKB1/SLC2A3/CTSB/QPCT/RAB27A/DOCK2/VCP/FPR1/RHOG/MNDA/PECAM1/STXBP2/FUCA1/PNP/HSP90AB1/PRDX6/SYK/FABP5/FRK/ITGAX/TSPAN14/SERPINB1/C6orf120/APAF1/ANPEP/HP/GLA/FPR2/CYBA/ADAM10/MAN2B1/CAT/ALAD/GOLGA7/CANT1/MANBA/NBEAL2/ITGAV/MVP/SLC2A5/FCGR3B/IQGAP2/RAB14/GSN/PTX3/ACTR2/ALOX5/CTSH	100
BP	GO:0002791	regulation of peptide secretion	102/2112	500/18670	1.797e-09	1.234e-07	8.919e-08	CCL5/AIM2/SFRP1/TNFAIP3/CD2/GBP1/IL27RA/IGF1/RASGRP1/TLR8/TNFRSF1B/MYH10/RHBDF2/FCN1/CCL19/SRI/OXCT1/PPP3CA/CCR7/ABCG1/TLR2/CD200/ANGPT1/CD74/TCIRG1/PAM/IL4R/LGALS9/NOD2/ADAM8/WLS/JAK2/IFIH1/ITSN1/CD40/HTR2B/TNFRSF14/SOCS1/RIPK2/FGR/CRTAM/EGFR/BTN2A2/HLA-E/SRGN/KLF7/TM7SF3/PASK/MPC2/IDH2/CD160/CLEC4E/AKAP12/TCF7L2/PER2/CD40LG/LRP5/TLR5/CADM1/RHBDF1/DDX58/CASP1/EFNA5/PTPN11/RBP4/ARNTL/SLC25A4/LEP/SSTR5/IFNG/OR51E2/PTGER4/STX4/SYK/HFE/TGFB3/SERPINB1/TNFRSF4/IL6/PTPN22/CD38/SYBU/ANXA4/NR1H3/ENSA/FERMT1/PPP1R11/SLC25A5/ANG/LYN/PANX1/HADH/LRRC32/SPTBN1/TLR6/IL1B/MMP12/PML/RAB11FIP1/LILRB1/GPR27/NLRP3	102
BP	GO:0002283	neutrophil activation involved in immune response	100/2112	488/18670	2.023e-09	1.374e-07	9.93e-08	AMPD3/CPNE3/SERPINA1/PTPRC/STK10/S100A9/TMC6/METTL7A/BIN2/TNFRSF1B/LILRB2/GCA/SERPINA3/FCN1/SLPI/COTL1/TLR2/TCIRG1/HBB/ITGB2/LILRA3/LRMP/SELL/ADAM8/LILRB3/CXCL1/CTSC/CD36/CFP/LYZ/RHOF/TIMP2/PLAC8/ANXA3/PGRMC1/FGR/ATP8A1/HK3/CYB5R3/PTPN6/ALDOC/HSPA6/ITGAL/CR1/PLEKHO2/MAGT1/CD93/PLD1/NCKAP1L/GMFG/CFD/CD53/NFKB1/SLC2A3/CTSB/QPCT/RAB27A/DOCK2/VCP/FPR1/RHOG/MNDA/PECAM1/STXBP2/FUCA1/PNP/HSP90AB1/PRDX6/SYK/FABP5/FRK/ITGAX/TSPAN14/SERPINB1/C6orf120/APAF1/ANPEP/HP/GLA/FPR2/CYBA/ADAM10/MAN2B1/CAT/ALAD/GOLGA7/CANT1/MANBA/NBEAL2/ITGAV/MVP/SLC2A5/FCGR3B/IQGAP2/RAB14/GSN/PTX3/ACTR2/ALOX5/CTSH	100
BP	GO:0140014	mitotic nuclear division	64/2112	264/18670	2.167e-09	1.456e-07	1.052e-07	BMP4/CDKN1C/IGF1/TACC3/BTC/PTTG1/PTTG3P/MKI67/BUB1/NFE2L1/NUSAP1/SIRT7/UBE2C/NCAPD2/NDC80/MAD2L1/GOLGA2/PLK1/TPX2/BORA/CDC14B/KIF11/CDCA8/NCAPH/KIF18B/SPHK1/RPL24/KIF3B/NCAPG/TPR/MAP9/DLGAP5/ZNF207/STAG2/BUB1B/KIF2C/LRP5/KIF4A/ARHGEF10/PRC1/NEK2/TOM1L1/ATRX/RACGAP1/ZWINT/CCNB1/FBXO5/NIPBL/CEP85/CENPF/TTK/CHMP2B/AURKB/RB1/CDC20/TUBG2/KIF20B/SMC4/TRIP13/AURKA/KIFC1/IL1B/CHMP1B/KIF23	64
BP	GO:1990868	response to chemokine	33/2112	97/18670	2.715e-09	1.786e-07	1.29e-07	CCL5/CXCL13/CXCL9/CCR5/XCL1/CCR2/CXCR4/CCL19/FOXC1/CCL13/CCR7/ACKR3/CXCL1/CXCL10/CXCL8/CCL21/CCR1/CX3CR1/CXCR6/CCL18/CXCL3/CXCL11/CCL7/SLC12A2/CXCL2/CCR8/CXCL5/CXCL6/SH2B3/CCL17/CCL2/CCRL2/CCL23	33
BP	GO:1990869	cellular response to chemokine	33/2112	97/18670	2.715e-09	1.786e-07	1.29e-07	CCL5/CXCL13/CXCL9/CCR5/XCL1/CCR2/CXCR4/CCL19/FOXC1/CCL13/CCR7/ACKR3/CXCL1/CXCL10/CXCL8/CCL21/CCR1/CX3CR1/CXCR6/CCL18/CXCL3/CXCL11/CCL7/SLC12A2/CXCL2/CCR8/CXCL5/CXCL6/SH2B3/CCL17/CCL2/CCRL2/CCL23	33
BP	GO:0002705	positive regulation of leukocyte mediated immunity	40/2112	133/18670	3.676e-09	2.392e-07	1.728e-07	XCL1/PTPRC/RASGRP1/HLA-F/HLA-A/HLA-C/SASH3/ITGB2/IL4R/HLA-G/NOD2/MALT1/CD40/MICB/GATA2/FGR/TFRC/CRTAM/HLA-E/SH2D1A/CD160/HLA-B/CD226/TBX21/CADM1/DDX58/VAV1/FAM49B/DDX1/STX4/SYK/STXBP1/BTK/IL6/IL18/GAB2/CD81/IL1R1/IL1B/NLRP3	40
BP	GO:0051607	defense response to virus	59/2112	238/18670	3.737e-09	2.407e-07	1.739e-07	TRAF3/AIM2/CXCL9/PTPRC/TNFAIP3/GBP1/PRF1/IRF1/RTP4/IRF9/BIRC3/TLR8/STAT1/IL15/SERINC3/OAS2/APOBEC3G/MX2/HTRA1/OAS1/IRF7/IFIH1/CD40/MICB/IRF2/CXCL10/APOBEC3B/TSPAN6/ISG20/IFI27/OASL/FAM111A/DDX58/PMAIP1/HERC5/ZMYND11/DDX60/IFIT3/IFNG/ADAR/DDX1/OAS3/TRIM22/IL6/TRIM38/IFIT5/PLSCR1/IFIT2/MX1/ZC3HAV1/IL2RA/BNIP3L/IFNA1/ISG15/IL1B/MMP12/PML/LILRB1/NLRP3	59
BP	GO:0071621	granulocyte chemotaxis	38/2112	123/18670	3.91e-09	2.493e-07	1.801e-07	CCL5/CXCL13/CXCL9/XCL1/S100A9/RAC2/CCL19/CCL13/CCR7/JAM3/CD74/ITGB2/CXCL1/DYSF/SCG2/CXCL10/THBS4/CXCL8/CCL21/CAMK1D/NCKAP1L/PIK3CD/CCL18/VAV1/HRH1/CXCL3/CXCL11/CCL7/SYK/CXCL2/CXCL5/CXCL6/IL1RN/CCL17/CCL2/CCL23/VAV3/IL1B	38
BP	GO:0001503	ossification	85/2112	398/18670	4.416e-09	2.776e-07	2.006e-07	ENPP1/NELL1/SFRP1/GDF5/BMP4/IGFBP5/ANKH/IGF1/DDR2/ZHX3/PENK/MGP/PTHLH/FGF18/SOX9/ZBTB16/SEMA4D/GLI3/LTBP3/FOXC1/SKI/TCIRG1/NPR2/KAZALD1/SLC26A2/BMPR1A/HDAC4/SIX2/COMP/SHOX2/TWSG1/FGR/EGFR/SRGN/DHRS3/TAC1/MRC2/MN1/HGF/CCR1/SOX2/ID3/PTN/LRP5/TP63/PBX1/DCHS1/VCAN/LEF1/SMAD3/KL/NOTCH1/MYOC/LEP/IL6ST/TOB1/CHRDL1/ADAR/SLC8A1/TFAP2A/ALPL/PTGER4/ACVR1/FBXO5/FGF9/TGFB3/NIPBL/WWTR1/EXT2/IL6/FAT4/BCAP29/BMP2K/PRKD1/CEBPA/FSTL3/SNX10/CAT/S1PR1/PTH1R/TOB2/SBNO2/ATRAID/ISG15/THRA	85
BP	GO:0002700	regulation of production of molecular mediator of immune response	41/2112	139/18670	4.446e-09	2.776e-07	2.006e-07	XCL1/PTPRC/CCR2/IL27RA/HLA-F/TNFRSF1B/SASH3/ANGPT1/CD74/IL4R/HLA-G/NOD2/MALT1/CD36/CD96/CD40/TNFRSF14/TFRC/HLA-E/CD160/CD226/TBX21/IL13RA2/CD40LG/DDX58/RBP4/DDX1/STX4/HFE/TGFB3/BTK/TNFRSF4/IL6/IL18/CD81/SPINK5/THOC1/IL1R1/IL1B/LILRB1/NLRP3	41
BP	GO:0071222	cellular response to lipopolysaccharide	53/2112	205/18670	4.85e-09	2.999e-07	2.167e-07	CCL5/CXCL13/CXCL9/CCR5/TNFAIP3/TNFRSF1B/LILRB2/IRF8/TLR2/AXL/ICAM1/NOD2/MALT1/CXCL1/TNIP2/CD36/CXCL10/RIPK2/CXCL8/PDCD1LG2/CX3CR1/NFKBIA/NFKB1/CD86/CASP1/CD6/CXCL3/KMO/CXCL11/CD80/EDNRB/GFI1/TNIP3/PAF1/IL6/SGMS1/PTPN22/CXCL2/CD180/NR1H3/CXCL5/LDOC1/CXCL6/IL18/TFPI/IL1RN/LYN/HCK/SBNO2/CCL2/IL1B/LILRB1/NLRP3	53
BP	GO:0007015	actin filament organization	85/2112	400/18670	5.662e-09	3.466e-07	2.504e-07	LCP1/WASF3/PIK3R1/SFRP1/LIMCH1/CORO1A/RAC2/ADD3/ARPIN/ARHGAP25/TMOD1/EFS/CCR7/LPAR1/COTL1/EMP2/RHOBTB3/HCLS1/PFN2/ITGB1BP1/MSRB2/ICAM1/JAK2/RHOF/COBL/WASL/PSTPIP2/TMSB10/DLC1/TAC1/CCL21/ARHGAP17/WAS/CDC42EP3/PLEK/RHOH/ENAH/SORBS2/GAS7/NOX4/NCKAP1L/GMFG/CAP2/ARHGEF10/PLS3/DSTN/SMAD3/VASP/ARPC5L/CORO2B/TNFAIP1/GPR65/MYOC/KANK1/RHOG/LMOD1/MICAL1/PPM1F/PTGER4/PAK1/MYO1C/DPYSL3/SORBS1/TGFB3/CTTN/RHOD/FER/CFL1/CAPZA1/VILL/AP1AR/ANG/HCK/ARPC1A/WASF2/WDR1/S1PR1/ABI2/ACTR3/PFN1/IQGAP2/SPTBN1/GSN/ARHGAP12/ACTR2	85
BP	GO:0071219	cellular response to molecule of bacterial origin	54/2112	212/18670	6.139e-09	3.722e-07	2.689e-07	CCL5/CXCL13/CXCL9/CCR5/TNFAIP3/TNFRSF1B/LILRB2/IRF8/TLR2/AXL/ICAM1/NOD2/MALT1/CXCL1/TNIP2/CD36/CXCL10/RIPK2/CXCL8/PDCD1LG2/CX3CR1/NFKBIA/NFKB1/CD86/CASP1/CD6/CXCL3/KMO/CXCL11/CD80/EDNRB/GFI1/TNIP3/PAF1/IL6/SGMS1/PTPN22/CXCL2/CD180/NR1H3/CXCL5/LDOC1/CXCL6/IL18/TFPI/IL1RN/LYN/HCK/SBNO2/CCL2/TLR6/IL1B/LILRB1/NLRP3	54
BP	GO:0002449	lymphocyte mediated immunity	77/2112	352/18670	7.847e-09	4.687e-07	3.387e-07	TRBC1/XCL1/PTPRC/CCR2/PRF1/IL27RA/CORO1A/RASGRP1/CLU/TLR8/HLA-F/TNFRSF1B/CD8A/HLA-A/RFTN1/IL7R/BATF/HLA-C/GZMB/SASH3/EMP2/CD74/TCIRG1/IL4R/HLA-G/ICAM1/LGALS9/IRF7/MALT1/CTSC/CD96/CD40/MICB/TFRC/CRTAM/HLA-E/PTPN6/SH2D1A/CR1/IGHM/IGLL5/CD160/HLA-B/WAS/CD226/TBX21/IL13RA2/KLRD1/CD27/CD40LG/CADM1/CD19/BTN3A3/RAB27A/VAV1/LEP/IGLC1/IGLV1-44/C7/FAM49B/HFE/BTK/IL6/IGHG1/INPP5D/IL18/SLAMF7/CD81/ERCC1/THOC1/IL1R1/IL1B/CR2/LILRB1/C6/CTSH/NLRP3	77
BP	GO:1902850	microtubule cytoskeleton organization involved in mitosis	39/2112	131/18670	7.884e-09	4.687e-07	3.387e-07	TACC3/NUSAP1/MAP4/NDC80/EML1/MAD2L1/GOLGA2/PLK1/TPX2/BORA/KIF11/KIF3B/TPR/TACC1/MAP9/ZNF207/STAG2/KIF4A/MCPH1/ARHGEF10/PRC1/NEK2/PLK2/RACGAP1/VCP/SPC25/TACC2/CCNB1/MECP2/TTK/CHMP2B/AURKB/CDC20/TUBG2/AURKA/KIFC1/CHMP1B/STIL/KIF23	39
BP	GO:0046638	positive regulation of alpha-beta T cell differentiation	21/2112	47/18670	8.134e-09	4.79e-07	3.461e-07	RUNX3/CCL19/ZBTB16/GLI3/SASH3/IL4R/LGALS9/MALT1/SOCS1/RIPK2/ADA/ZAP70/NCKAP1L/CD86/CD83/IFNG/PNP/SYK/CD80/IL18/NLRP3	21
BP	GO:0002456	T cell mediated immunity	34/2112	106/18670	8.787e-09	5.125e-07	3.703e-07	XCL1/PTPRC/CCR2/PRF1/HLA-F/TNFRSF1B/CD8A/HLA-A/RFTN1/IL7R/HLA-C/SASH3/EMP2/HLA-G/ICAM1/MALT1/CTSC/MICB/HLA-E/HLA-B/WAS/TBX21/BTN3A3/RAB27A/FAM49B/HFE/IL6/IL18/CD81/IL1R1/IL1B/LILRB1/CTSH/NLRP3	34
BP	GO:0030278	regulation of ossification	52/2112	203/18670	9.489e-09	5.483e-07	3.962e-07	ENPP1/NELL1/SFRP1/BMP4/IGFBP5/ANKH/IGF1/DDR2/ZHX3/MGP/SOX9/ZBTB16/SEMA4D/GLI3/LTBP3/SKI/TCIRG1/BMPR1A/HDAC4/SIX2/COMP/TWSG1/SRGN/DHRS3/TAC1/HGF/CCR1/ID3/PTN/LRP5/TP63/PBX1/SMAD3/KL/NOTCH1/IL6ST/TOB1/SLC8A1/TFAP2A/PTGER4/ACVR1/FBXO5/TGFB3/NIPBL/IL6/BMP2K/PRKD1/CEBPA/S1PR1/TOB2/ATRAID/ISG15	52
BP	GO:2000516	positive regulation of CD4-positive, alpha-beta T cell activation	18/2112	36/18670	1.04e-08	5.955e-07	4.302e-07	XCL1/PRKCQ/CCL19/SASH3/IL4R/LGALS9/MALT1/SOCS1/RIPK2/CD160/NCKAP1L/CD86/CD83/IFNG/CD80/IL18/CD81/NLRP3	18
BP	GO:0035710	CD4-positive, alpha-beta T cell activation	31/2112	92/18670	1.059e-08	6.007e-07	4.34e-07	RELB/PLA2G2D/XCL1/RUNX3/SEMA4A/PRKCQ/GPR183/CCL19/BATF/SASH3/IRF4/TCIRG1/IL4R/LGALS9/MALT1/SOCS1/TWSG1/RIPK2/CD160/TBX21/NCKAP1L/CD86/CD83/LEF1/IFNG/PTGER4/CD80/IL6/IL18/CD81/NLRP3	31
BP	GO:0001909	leukocyte mediated cytotoxicity	34/2112	107/18670	1.149e-08	6.459e-07	4.667e-07	XCL1/PTPRC/PRF1/CORO1A/RASGRP1/HLA-F/HLA-A/IL7R/HLA-C/GZMB/EMP2/HLA-G/ICAM1/LGALS9/CTSC/MICB/CRTAM/HLA-E/PTPN6/SH2D1A/CD160/HLA-B/CD226/CADM1/RAB27A/VAV1/LEP/STXBP2/FAM49B/CXCL6/IL18/SLAMF7/LILRB1/CTSH	34
BP	GO:0002706	regulation of lymphocyte mediated immunity	42/2112	149/18670	1.274e-08	7.096e-07	5.127e-07	XCL1/PTPRC/CCR2/IL27RA/RASGRP1/HLA-F/TNFRSF1B/HLA-A/IL7R/HLA-C/SASH3/HLA-G/LGALS9/MALT1/CD96/CD40/MICB/TFRC/CRTAM/HLA-E/PTPN6/SH2D1A/CR1/CD160/HLA-B/WAS/CD226/TBX21/CADM1/VAV1/LEP/FAM49B/HFE/BTK/IL6/IL18/CD81/THOC1/IL1R1/IL1B/LILRB1/NLRP3	42
BP	GO:0002576	platelet degranulation	38/2112	128/18670	1.33e-08	7.33e-07	5.296e-07	SERPINA1/IGF1/TIMP3/CLU/SERPINA3/ABCC4/ENDOD1/MAGED2/CD36/TUBA4A/CTSW/SRGN/PROS1/F5/PHACTR2/GTPBP2/PLEK/HGF/CFD/SOD1/FAM3C/APOOL/CYB5R1/CD9/PECAM1/STXBP2/FAM49B/SYK/STXBP1/TGFB3/CDC37L1/APLP2/VEGFB/LYN/WDR1/VTI1B/NHLRC2/ISLR	38
BP	GO:1903557	positive regulation of tumor necrosis factor superfamily cytokine production	30/2112	88/18670	1.34e-08	7.33e-07	5.296e-07	PIK3R1/PTPRC/CD2/CCR2/RASGRP1/CLU/ZBTB20/CCL19/SASH3/TLR2/LGALS9/NOD2/ADAM8/JAK2/CD36/IFIH1/RIPK2/HLA-E/CLEC7A/AKAP12/DDX58/CD86/PTPN11/LEP/IFNG/SYK/HSPB1/MAPKAPK2/CYBA/NOD1	30
BP	GO:0007204	positive regulation of cytosolic calcium ion concentration	71/2112	319/18670	1.414e-08	7.672e-07	5.543e-07	CXCL13/CXCL9/CCR5/XCL1/LCK/PTPRC/CCR2/LRP6/CORO1A/PLCE1/CXCR4/CCL19/SRI/CACNA2D1/ANK2/CCR7/LPAR1/CD52/ACKR3/JAK2/CD36/HTR2B/GATA2/CXCL10/PTPN6/FGF2/GPR18/TAC1/PLCG2/CCL21/NMB/BAK1/CCR1/CX3CR1/PLN/CXCR6/MS4A1/TRPC1/HTR2A/CD19/GPR65/FPR1/AGTR1/ATP1A2/CXCL11/PTGFR/SLC8A1/PTGER4/P2RY6/APLNR/EDNRB/CD38/DDIT3/CCR8/RYR3/RIC3/FPR2/CYBA/LYN/PKD2/GSTO1/GSTM2/S1PR1/PTH1R/TGM2/ITGAV/S1PR4/GPR4/CCRL2/P2RY4/PML	71
BP	GO:0046633	alpha-beta T cell proliferation	17/2112	33/18670	1.498e-08	8.051e-07	5.817e-07	XCL1/CD3E/PTPRC/CCR2/IRF1/IL15/ELF4/LGALS9/TNFRSF14/TWSG1/RIPK2/HLA-E/ZAP70/DOCK2/SYK/IL18/CD81	17
BP	GO:0002718	regulation of cytokine production involved in immune response	29/2112	84/18670	1.684e-08	8.977e-07	6.486e-07	XCL1/CCR2/HLA-F/TNFRSF1B/SASH3/ANGPT1/CD74/HLA-G/NOD2/MALT1/CD36/CD96/TNFRSF14/HLA-E/CD160/CD226/TBX21/DDX58/DDX1/HFE/TGFB3/BTK/IL6/IL18/CD81/IL1R1/IL1B/LILRB1/NLRP3	29
BP	GO:0019058	viral life cycle	72/2112	328/18670	2.054e-08	1.085e-06	7.842e-07	CCL5/LAMP3/CCR5/SLAMF1/ITGB7/CXCR4/FCN1/SLPI/NUCKS1/CD74/AXL/APOBEC3G/OAS1/ICAM1/LGALS9/NUP93/TNFRSF14/TFRC/EGFR/DAG1/ISG20/PC/NPC1/SRPK1/IFI27/OASL/CXCL8/CR1/TPR/CDK1/CXCR6/FAM111A/NUP160/TOP2A/CD86/HTR2A/CTSB/TRIM21/HYAL1/VPS37C/NOTCH1/FBXL2/VCP/ADAR/MPHOSPH8/HSP90AB1/OAS3/CD80/TNFRSF4/SCARB2/ANPEP/SELPLG/TRIM38/IFIT5/CHMP2B/PLSCR1/KPNA2/TRIM26/DDX6/NUP88/CD81/MX1/ZC3HAV1/NUP50/ITGAV/CCL2/ISG15/GSN/CR2/PTX3/CHMP1B/PML	72
BP	GO:0051091	positive regulation of DNA-binding transcription factor activity	61/2112	261/18670	2.222e-08	1.162e-06	8.397e-07	AIM2/S100A9/LRP6/DDR2/PRKCH/CLU/TRAF1/PRKCQ/MYD88/PPP3CA/NFKB2/PRKCB/TLR2/CD200/HCLS1/ITGB2/AR/ICAM1/LGALS9/NOD2/MALT1/ADAM8/JAK2/CD36/HDAC4/CD40/PRKD2/ANXA3/RIPK2/SPHK1/CX3CR1/CAMK1D/CD40LG/RPS6KA4/DDX58/NFKB1/FZD4/TRIM21/SMAD3/FOSL1/IKBKG/TRIM22/PINK1/BTK/IL6/FER/TRIM38/DDIT3/IL18/TRIM26/PRKD1/MBTPS2/NOD1/RWDD1/HIPK2/CFLAR/CAT/FZD2/TLR6/IL1B/NLRP3	61
BP	GO:0043900	regulation of multi-organism process	84/2112	405/18670	2.237e-08	1.162e-06	8.397e-07	CCL5/LAMP3/TRAF3/AIM2/TNFAIP3/PRF1/IGF1/BIRC3/ARHGDIB/STAT1/CXCR4/FCN1/IL15/SLPI/NUCKS1/INHBA/CD74/APOBEC3G/CHD1/NPR2/HTRA1/OAS1/LGALS9/CD36/HDAC4/MICB/RIPK2/ADA/TSPAN6/ISG20/PC/SRPK1/CLEC7A/IFI27/OASL/CXCL8/CCNT1/SP1/FAM111A/HPGDS/TOP2A/DDX58/LEF1/TRIM21/HERC5/NOTCH1/FBXL2/GTF2F1/DDX60/IFNG/ADAR/MPHOSPH8/KRT6A/OAS3/SYK/POLR2L/EDNRB/STXBP1/CD180/TRIM38/IFIT5/CHMP2B/PLSCR1/CFL1/KPNA2/CXCL6/RSF1/CYBA/TRIM26/NOD1/OVGP1/MX1/ZC3HAV1/SPINK5/IL2RA/ITGAV/AURKA/ISG15/GSN/IL1B/MMP12/PTX3/PML/LILRB1	84
BP	GO:1903555	regulation of tumor necrosis factor superfamily cytokine production	44/2112	163/18670	2.417e-08	1.245e-06	8.997e-07	PIK3R1/PTPRC/TNFAIP3/CD2/CCR2/IL27RA/IGF1/SLAMF1/RASGRP1/CLU/ZBTB20/CCL19/SASH3/TLR2/ANGPT1/AXL/LGALS9/NOD2/ADAM8/JAK2/CD36/IFIH1/RIPK2/HLA-E/PTPN6/GPR18/CLEC7A/AKAP12/CX3CR1/DDX58/CD86/PTPN11/LEP/IFNG/CLEC4A/ADIPOQ/SYK/HSPB1/MAPKAPK2/PTPN22/UBE2J1/CYBA/NOD1/LILRB1	44
BP	GO:0070371	ERK1 and ERK2 cascade	70/2112	317/18670	2.501e-08	1.278e-06	9.235e-07	CCL5/XCL1/PTPRC/BMP4/GBP1/IGF1/SLAMF1/RASGRP1/CSK/TIMP3/LMO3/FGF18/GPR183/CCL19/SOX9/CCL13/CCR7/ANGPT1/CD74/PTPN2/ITGB1BP1/ICAM1/LGALS9/ACKR3/NOD2/CD36/PDGFD/PRKD2/HTR2B/RIPK2/EGFR/BTN2A2/PTPN6/FGF2/CCL21/ERBB2/AKAP12/CCR1/EPHB1/NOX4/CCL18/RRAS/HTR2A/PTPN11/MFHAS1/NOTCH1/ZFP36L1/FLT3/PTGER4/CCL7/ADIPOQ/SYK/P2RY6/HCRTR1/PTPN22/DUSP6/FPR2/FBLN1/LYN/NOD1/KDR/CFLAR/CCL17/ZFP36L2/ITGAV/CCL2/NDRG2/CCL23/IL1B/CTSH	70
BP	GO:0050730	regulation of peptidyl-tyrosine phosphorylation	60/2112	256/18670	2.592e-08	1.314e-06	9.492e-07	CCL5/KITLG/CD3E/SFRP1/PTPRC/CRLF1/IGF1/IL15/SEMA4D/NTRK2/SH3BP5/PPP2CA/ANGPT1/FGF7/CD74/PTPN2/HCLS1/ITGB2/ICAM1/JAK2/SAMSN1/CD36/PDGFD/CD40/TNFRSF14/SOCS1/RIPK2/EGFR/GPRC5A/HBEGF/PTPN6/THBS4/CSPG4/GHR/HGF/ZGPAT/EHD4/NOX4/HTR2A/EFNA5/PTPN11/LEP/IL6ST/IFNG/PECAM1/FLT3/ADIPOQ/SYK/CD80/TEC/ACVR1/CTF1/IL6/IL18/LYN/SH2B3/CD81/NCF1/TP53/MVP	60
BP	GO:0002262	myeloid cell homeostasis	41/2112	147/18670	2.631e-08	1.322e-06	9.555e-07	KITLG/AMPD3/CCR2/BMP4/RBFOX2/STAT1/INHBA/NFE2L1/JAM3/AXL/PTPN2/HCLS1/JAK2/GATA2/TGFBR3/BAK1/NCKAP1L/PIK3CD/SOD1/MFHAS1/P4HTM/ZFP36L1/ARNT/ADAR/TRIM58/SPI1/IL6/INPP5D/FOXO3/RB1/LYN/SH2B3/HIPK2/IKZF1/MERTK/PRMT1/ISG15/PTBP3/RPS14/HOXA5/THRA	41
BP	GO:0045089	positive regulation of innate immune response	80/2112	381/18670	2.754e-08	1.373e-06	9.92e-07	CCL5/TRAF3/AIM2/PSMB9/RELB/TNFAIP3/S100A9/PSMB8/IRF1/RASGRP1/BIRC3/TLR8/HLA-F/RFTN1/CLEC10A/FCN1/PSMB10/MYD88/SKP1/TLR2/IRF4/ITGB2/HLA-G/NOD2/COCH/IRF7/MALT1/ADAM8/TNIP2/CD36/IFIH1/MICB/CTSL/PSME1/RIPK2/CRTAM/HLA-E/TSPAN6/CREBBP/CLEC7A/SH2D1A/PLCG2/CD160/CLEC4E/TXK/CD226/NFKBIA/TLR5/CADM1/DDX58/PTPRS/NFKB1/ICAM3/CTSB/VAV1/MFHAS1/UBE2D1/COLEC12/HEXIM1/DDX60/MNDA/CLEC4A/PAK1/SYK/GFI1/IKBKG/TNIP3/BTK/MAPKAPK2/PTPN22/PLSCR1/NR1H3/FPR2/CYBA/LYN/NOD1/HCK/RAB11FIP2/TLR6/MMP12	80
BP	GO:0007088	regulation of mitotic nuclear division	44/2112	164/18670	2.946e-08	1.447e-06	1.046e-06	BMP4/CDKN1C/IGF1/TACC3/BTC/PTTG1/PTTG3P/MKI67/BUB1/NFE2L1/NUSAP1/UBE2C/NDC80/MAD2L1/PLK1/BORA/CDC14B/KIF11/SPHK1/TPR/MAP9/DLGAP5/ZNF207/STAG2/BUB1B/LRP5/NEK2/TOM1L1/ATRX/CCNB1/FBXO5/NIPBL/CEP85/CENPF/TTK/CHMP2B/AURKB/RB1/CDC20/KIF20B/TRIP13/AURKA/IL1B/CHMP1B	44
BP	GO:0032970	regulation of actin filament-based process	81/2112	388/18670	2.95e-08	1.447e-06	1.046e-06	PIK3R1/SFRP1/EPHA3/LIMCH1/CORO1A/ADD3/ARHGDIB/ARPIN/TMOD1/SRI/ANK2/CCR7/LPAR1/COTL1/JAM3/RHOBTB3/HCLS1/PFN2/ITGB1BP1/PAM/ICAM1/RHOF/WASL/TMSB10/PDPN/DLC1/TAC1/FGF13/CCL21/ARHGAP17/WAS/CDC42EP3/PLEK/RHOH/PLN/NOX4/NCKAP1L/GMFG/ARHGEF10/KCNJ2/DSTN/EFNA5/SMAD3/VASP/DIXDC1/ARPC5L/CORO2B/GPR65/MYOC/ECT2/KANK1/DSC2/RHOG/LMOD1/ATP1A2/PPM1F/PTGER4/PAK1/MYO1C/TGFB3/CTTN/RHOD/AKAP13/FER/CFL1/CAPZA1/VILL/AP1AR/SEMA3E/HCK/ARPC1A/WASF2/WDR1/S1PR1/ABI2/ACTR3/PFN1/IQGAP2/SPTBN1/GSN/ACTR2	81
BP	GO:0050707	regulation of cytokine secretion	52/2112	210/18670	3.223e-08	1.569e-06	1.134e-06	AIM2/TNFAIP3/CD2/GBP1/IL27RA/RASGRP1/TLR8/TNFRSF1B/FCN1/CCL19/CCR7/TLR2/CD200/ANGPT1/IL4R/LGALS9/NOD2/IFIH1/HTR2B/TNFRSF14/SOCS1/RIPK2/FGR/CRTAM/BTN2A2/SRGN/CD160/CLEC4E/AKAP12/TLR5/CADM1/DDX58/CASP1/IFNG/PTGER4/SYK/SERPINB1/TNFRSF4/PTPN22/ANXA4/FERMT1/PPP1R11/LYN/PANX1/LRRC32/SPTBN1/TLR6/IL1B/MMP12/PML/LILRB1/NLRP3	52
BP	GO:0048010	vascular endothelial growth factor receptor signaling pathway	31/2112	96/18670	3.297e-08	1.593e-06	1.151e-06	PIK3R1/FGF18/FOXC1/PRKCB/AXL/SH2D2A/SULF1/PRKD2/SHB/NCF4/DOCK1/NCKAP1L/FZD4/CYFIP2/TNMD/VAV1/ARNT/PIK3CA/FGF9/HSPB1/MAPKAPK2/CYBA/VEGFB/PRKD1/KDR/SHC2/WASF2/NCF1/ITGAV/VAV3/IL1B	31
BP	GO:0002483	antigen processing and presentation of endogenous peptide antigen	11/2112	15/18670	3.35e-08	1.594e-06	1.151e-06	TAP1/TAPBP/HLA-F/HLA-A/TAP2/HLA-C/HLA-G/ERAP2/HLA-E/HLA-B/HFE	11
BP	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	11/2112	15/18670	3.35e-08	1.594e-06	1.151e-06	TAP1/TAPBP/HLA-F/HLA-A/TAP2/HLA-C/HLA-G/ERAP2/HLA-E/HLA-B/HFE	11
BP	GO:0006979	response to oxidative stress	90/2112	451/18670	4.791e-08	2.261e-06	1.634e-06	PLEKHA1/TNFAIP3/SCARA3/PENK/GCH1/NQO1/STAT1/CCL19/VRK2/AKR1C3/MCTP1/CCR7/NFE2L1/AXL/ACOX2/SIGMAR1/NDUFS2/HBB/MSRB2/OXR1/CRYAB/JAK2/CD36/PDGFD/MICB/EGFR/FBLN5/MELK/ADA/ETV5/SPHK1/ANGPTL7/LANCL1/CDK1/BAK1/HGF/SP1/CCNA2/EZH2/NCF4/NOX4/SOD1/MAPK13/ARL6IP5/PPP2CB/GPX3/IPCEF1/FOXO1/NET1/HYAL1/GPX4/ARNTL/ECT2/ARNT/RGN/PDLIM1/SLC8A1/ADIPOQ/STX4/PRDX6/FOSL1/PARP1/HSPB1/PINK1/BTK/PTGS1/IL6/CD38/FER/HP/FOXO3/CYBA/PRKD1/SESN1/RWDD1/SLC23A2/PKD2/BAG5/FUT8/CFLAR/CAT/NCF1/ERCC1/PRR5L/ALAD/TP53/TLR6/PML/PSIP1/TXN2	90
BP	GO:0055074	calcium ion homeostasis	93/2112	471/18670	4.854e-08	2.274e-06	1.643e-06	CCL5/CXCL13/CXCL9/CCR5/XCL1/LCK/PTPRC/CCR2/LRP6/CORO1A/PLCE1/CXCR4/CCL19/SRI/CACNA2D1/CCL13/ANK2/CCR7/LPAR1/PRKCB/TCIRG1/CD52/ACKR3/JAK2/CD36/CD40/HTR2B/GATA2/CXCL10/TRIM24/PTPN6/FGF2/GPR18/TAC1/PLCG2/CCL21/NMB/BAK1/CCR1/CX3CR1/PLN/CXCR6/AFG3L2/MICU1/SGCD/MS4A1/TRPC1/HTR2A/CD19/ATP1B1/SMAD3/KL/GPR65/ATP13A3/FPR1/AGTR1/RGN/ATP1A2/CXCL11/PTGFR/SLC8A1/PTGER4/CCL7/P2RY6/APLNR/EDNRB/SLC25A23/HCRTR1/CD38/DDIT3/CCR8/RYR3/RIC3/FPR2/CYBA/LYN/SNX10/PKD2/GSTO1/GSTM2/S1PR1/PTH1R/TGM2/ITGAV/S1PR4/GPR4/CCRL2/CCL23/EPHX2/P2RY4/CDH5/PML/ATP2A3	93
BP	GO:0031589	cell-substrate adhesion	75/2112	354/18670	5.048e-08	2.342e-06	1.692e-06	PIK3R1/NDNF/CD3E/SFRP1/EPHA3/GBP1/LIMCH1/CORO1A/DDR2/TMEM8B/ITGB7/RAC2/SPOCK2/ITGA4/SPOCK1/CCR7/ANTXR1/JAM3/EMP2/ANGPT1/AXL/ITGB1BP1/ITGB2/ECM2/FERMT2/JAK2/CD36/CD96/FBLN5/PDPN/DAG1/ITGBL1/DLC1/LYVE1/ITGAL/COL8A1/CCL21/SGCE/EDIL3/EPHB1/PTN/DOCK1/PARVA/SKAP1/FZD4/EFNA5/SMAD3/HSD17B12/FZD7/CORO2B/NOTCH1/MYOC/ITGA10/KANK1/TIMM10B/PECAM1/PPM1F/TRIP6/PLEKHA2/SORBS1/CTTN/RHOD/FER/AP1AR/FBLN1/FERMT1/SEMA3E/AKIP1/KDR/MERTK/ITGAV/CASK/LIMS2/COL16A1/MMP12	75
BP	GO:2000107	negative regulation of leukocyte apoptotic process	20/2112	47/18670	5.076e-08	2.342e-06	1.692e-06	CCL5/KITLG/CCR5/BMP4/IDO1/PRKCQ/CCL19/IL7R/CCR7/CD74/AXL/HCLS1/NOD2/IRF7/ADA/CCL21/CD27/AURKB/MERTK/LILRB1	20
BP	GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	76/2112	361/18670	5.437e-08	2.49e-06	1.799e-06	CXCL13/RELB/TRBC1/XCL1/PTPRC/TNFAIP3/CCR2/PRF1/IL27RA/SEMA4A/CLU/TLR8/HLA-F/TNFRSF1B/CD8A/HLA-A/RFTN1/PRKCQ/CCL19/IL7R/BATF/HLA-C/NFKB2/SASH3/IRF4/EMP2/CD74/TCIRG1/IL4R/HLA-G/ICAM1/IRF7/MALT1/CTSC/CD40/MICB/RIPK2/TFRC/HLA-E/ADA/PTPN6/CR1/IGHM/IGLL5/HLA-B/WAS/CD226/TBX21/IL13RA2/CD27/CD40LG/CD19/LEF1/BTN3A3/RAB27A/IGLC1/IGLV1-44/C7/FAM49B/CD80/HFE/BTK/IL6/IGHG1/INPP5D/IL18/CD81/ERCC1/THOC1/IL1R1/IL1B/CR2/LILRB1/C6/CTSH/NLRP3	76
BP	GO:0050764	regulation of phagocytosis	31/2112	98/18670	5.646e-08	2.567e-06	1.855e-06	IL2RG/PTPRC/CSK/IL15RA/IL2RB/IL15/SIRPG/TLR2/DYSF/CD36/GATA2/FGR/SPHK1/CLEC7A/CAMK1D/NCKAP1L/SOD1/RAB27A/DOCK2/IFNG/ADIPOQ/ATG3/SYK/FPR2/CYBA/HCK/MERTK/ITGAV/CCL2/IL1B/PTX3	31
BP	GO:0032956	regulation of actin cytoskeleton organization	73/2112	343/18670	6.258e-08	2.824e-06	2.041e-06	PIK3R1/SFRP1/EPHA3/LIMCH1/CORO1A/ADD3/ARHGDIB/ARPIN/TMOD1/CCR7/LPAR1/COTL1/JAM3/RHOBTB3/HCLS1/PFN2/ITGB1BP1/PAM/ICAM1/RHOF/WASL/TMSB10/DLC1/TAC1/CCL21/ARHGAP17/WAS/CDC42EP3/PLEK/RHOH/NOX4/NCKAP1L/GMFG/ARHGEF10/DSTN/EFNA5/SMAD3/VASP/DIXDC1/ARPC5L/CORO2B/GPR65/MYOC/ECT2/KANK1/RHOG/LMOD1/PPM1F/PTGER4/PAK1/MYO1C/TGFB3/CTTN/RHOD/AKAP13/FER/CFL1/CAPZA1/VILL/AP1AR/SEMA3E/HCK/ARPC1A/WASF2/WDR1/S1PR1/ABI2/ACTR3/PFN1/IQGAP2/SPTBN1/GSN/ACTR2	73
BP	GO:0071706	tumor necrosis factor superfamily cytokine production	44/2112	168/18670	6.362e-08	2.851e-06	2.06e-06	PIK3R1/PTPRC/TNFAIP3/CD2/CCR2/IL27RA/IGF1/SLAMF1/RASGRP1/CLU/ZBTB20/CCL19/SASH3/TLR2/ANGPT1/AXL/LGALS9/NOD2/ADAM8/JAK2/CD36/IFIH1/RIPK2/HLA-E/PTPN6/GPR18/CLEC7A/AKAP12/CX3CR1/DDX58/CD86/PTPN11/LEP/IFNG/CLEC4A/ADIPOQ/SYK/HSPB1/MAPKAPK2/PTPN22/UBE2J1/CYBA/NOD1/LILRB1	44
BP	GO:0050854	regulation of antigen receptor-mediated signaling pathway	24/2112	65/18670	6.545e-08	2.911e-06	2.103e-06	LCK/PTPRC/GBP1/PVRIG/LPXN/PRKCH/TRAT1/CCR7/PRKCB/PTPN2/MALT1/PRKD2/BTN2A2/ADA/PTPN6/CD160/CD226/LILRB4/CD19/PAX5/PTPN22/LYN/CD81/UBASH3A	24
BP	GO:0071887	leukocyte apoptotic process	32/2112	104/18670	7.208e-08	3.184e-06	2.3e-06	CCL5/KITLG/CCR5/BMP4/IDO1/PRKCQ/CCL19/IL7R/GLI3/CCR7/CD74/AXL/HCLS1/CD3G/LGALS9/NOD2/IRF7/ADAM8/CTSL/ADA/CCL21/BAK1/CD27/PIK3CD/BTK/IL6/AURKB/LYN/MERTK/IL2RA/TP53/LILRB1	32
BP	GO:0014065	phosphatidylinositol 3-kinase signaling	40/2112	148/18670	9.938e-08	4.358e-06	3.149e-06	CCL5/PLEKHA1/PIK3R1/IGF1/RASGRP1/SOX9/SEMA4D/NTRK2/ANGPT1/HCLS1/JAK2/PDGFD/PIP4K2B/HTR2B/FGR/EGFR/BTN2A2/PTPN6/DCN/CEP55/CD160/ERBB2/HGF/PPP1R16B/PIK3CD/HTR2A/PTPN13/FBXL2/MYOC/LEP/ZFP36L1/PIK3CA/FLT3/PIP4K2A/IL18/LYN/KDR/CAT/NCF1/PRR5L	40
BP	GO:0032680	regulation of tumor necrosis factor production	42/2112	160/18670	1.174e-07	5.112e-06	3.693e-06	PIK3R1/PTPRC/TNFAIP3/CD2/CCR2/IL27RA/IGF1/SLAMF1/RASGRP1/CLU/ZBTB20/CCL19/SASH3/TLR2/ANGPT1/AXL/LGALS9/NOD2/JAK2/CD36/IFIH1/RIPK2/HLA-E/PTPN6/GPR18/CLEC7A/AKAP12/CX3CR1/DDX58/PTPN11/LEP/IFNG/CLEC4A/ADIPOQ/SYK/HSPB1/MAPKAPK2/PTPN22/UBE2J1/CYBA/NOD1/LILRB1	42
BP	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	46/2112	183/18670	1.221e-07	5.281e-06	3.816e-06	BIRC3/CCL19/SECTM1/MYD88/CCR7/LPAR1/PRKCB/CD74/TNFSF10/LGALS9/NOD2/MALT1/WLS/TNIP2/CD36/APOL3/CD40/HTR2B/RIPK2/TSPAN6/CASP10/CCL21/S100A13/CX3CR1/CASP1/PLK2/BRD4/ECT2/DDX1/ADIPOQ/IKBKG/TRIM22/PINK1/AKAP13/TRIM38/IFIT5/IL1RN/PRKD1/NOD1/NDFIP1/CFLAR/TGM2/CANT1/PIM2/TLR6/IL1B	46
BP	GO:0032760	positive regulation of tumor necrosis factor production	28/2112	86/18670	1.237e-07	5.31e-06	3.836e-06	PIK3R1/PTPRC/CD2/CCR2/RASGRP1/CLU/ZBTB20/CCL19/SASH3/TLR2/LGALS9/NOD2/JAK2/CD36/IFIH1/RIPK2/HLA-E/CLEC7A/AKAP12/DDX58/PTPN11/LEP/IFNG/SYK/HSPB1/MAPKAPK2/CYBA/NOD1	28
BP	GO:0048017	inositol lipid-mediated signaling	46/2112	184/18670	1.453e-07	6.194e-06	4.475e-06	CCL5/PLEKHA1/PIK3R1/IGF1/RASGRP1/PLCE1/SOX9/SEMA4D/NTRK2/ANGPT1/HCLS1/JAK2/PDGFD/PIP4K2B/HTR2B/FGR/EGFR/BTN2A2/PTPN6/DCN/CEP55/PLCG2/CD160/ERBB2/HGF/PLD1/PPP1R16B/PIK3CD/HTR2A/PTPN13/FBXL2/MYOC/LEP/ZFP36L1/PIK3CA/FLT3/PIP4K2A/IL18/GAB2/LYN/KDR/CAT/NCF1/NPR3/PRR5L/GSN	46
BP	GO:0002720	positive regulation of cytokine production involved in immune response	21/2112	54/18670	1.535e-07	6.487e-06	4.687e-06	XCL1/HLA-F/SASH3/CD74/HLA-G/NOD2/MALT1/CD36/TNFRSF14/HLA-E/CD160/CD226/DDX58/DDX1/IL6/IL18/CD81/IL1R1/IL1B/LILRB1/NLRP3	21
BP	GO:0002685	regulation of leukocyte migration	48/2112	196/18670	1.542e-07	6.487e-06	4.687e-06	CCL5/CXCL13/SLAMF8/KITLG/XCL1/CCR2/STK10/IL27RA/RAC2/CCL19/ITGA4/CCR7/JAM3/CD200/CD74/ICAM1/LGALS9/ADAM8/DYSF/PDGFD/WASL/TNFRSF14/GPSM3/CXCL10/ADA/GPR18/THBS4/CXCL8/CCL21/CCR1/CX3CR1/CAMK1D/PTN/NCKAP1L/CD9/NBL1/PTGER4/CCL7/IL6/FPR2/ADAM10/VEGFB/MTUS1/LYN/CD81/CCL2/IL1R1/PLA2G7	48
BP	GO:0046637	regulation of alpha-beta T cell differentiation	23/2112	63/18670	1.56e-07	6.515e-06	4.707e-06	RUNX3/CCL19/ZBTB16/GLI3/SASH3/IRF4/IL4R/LGALS9/MALT1/SOCS1/RIPK2/ADA/ZAP70/TBX21/NCKAP1L/CD86/CD83/IFNG/PNP/SYK/CD80/IL18/NLRP3	23
BP	GO:1904951	positive regulation of establishment of protein localization	89/2112	456/18670	1.619e-07	6.72e-06	4.856e-06	AIM2/PIK3R1/CD2/TFDP2/IGF1/ZIC1/RASGRP1/TLR8/RAC2/MYH10/FCN1/CCL19/SRI/GLI3/OXCT1/GZMB/ABCG1/TLR2/BID/HCLS1/ITGB1BP1/ITGB2/IL4R/LGALS9/NOD2/ADAM8/WLS/JAK2/IFIH1/HTR2B/TNFRSF14/RIPK2/FGR/CRTAM/EGFR/HLA-E/TM7SF3/MPC2/TPR/CD160/CLEC4E/ERBB2/AKAP12/TCF7L2/CEP135/TP63/CADM1/ZPR1/DDX58/CASP1/PMAIP1/SMAD3/EDEM1/CORO2B/RBP4/ECT2/LEP/IFNG/OR51E2/PTGER4/PAK1/MYO1C/STX4/SYK/ZFAND1/VAMP2/TGFB3/PINK1/TNFRSF4/IL6/PTPN22/CD38/SYBU/FERMT1/ANG/PANX1/HSPA1L/KIF20B/TP53BP2/CD81/EDEM2/PRR5L/TP53/SPTBN1/IL1B/MMP12/XPO4/GPR27/NLRP3	89
BP	GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	39/2112	145/18670	1.643e-07	6.773e-06	4.894e-06	XCL1/PTPRC/TNFAIP3/CCR2/IL27RA/HLA-F/TNFRSF1B/HLA-A/PRKCQ/CCL19/IL7R/HLA-C/SASH3/IL4R/HLA-G/MALT1/CD40/RIPK2/TFRC/HLA-E/ADA/PTPN6/CR1/HLA-B/WAS/CD226/TBX21/FAM49B/CD80/HFE/BTK/IL6/IL18/CD81/THOC1/IL1R1/IL1B/LILRB1/NLRP3	39
BP	GO:0032743	positive regulation of interleukin-2 production	15/2112	30/18670	1.785e-07	7.309e-06	5.281e-06	CD3E/PTPRC/CCR2/PRKCQ/SASH3/IRF4/MALT1/PRKD2/RIPK2/CLEC7A/CD86/CD83/CD80/SPTBN1/IL1B	15
BP	GO:0001906	cell killing	43/2112	168/18670	1.808e-07	7.353e-06	5.312e-06	XCL1/PTPRC/PRF1/CORO1A/RASGRP1/HLA-F/HLA-A/APOL1/IL7R/HLA-C/CCL13/GZMB/EMP2/GNLY/HLA-G/ICAM1/LGALS9/CTSC/LYZ/MICB/CRTAM/HLA-E/PTPN6/CLEC7A/SH2D1A/CD160/HLA-B/CD226/CADM1/RAB27A/VAV1/LEP/IFNG/STXBP2/FAM49B/HSP90AB1/KRT6A/SYK/CXCL6/IL18/SLAMF7/LILRB1/CTSH	43
BP	GO:0032945	negative regulation of mononuclear cell proliferation	25/2112	73/18670	1.927e-07	7.736e-06	5.59e-06	PLA2G2D/XCL1/CTLA4/BMP4/IDO1/DLG5/LILRB2/HLA-G/LGALS9/TNFRSF14/TWSG1/BTN2A2/PTPN6/ERBB2/PDCD1LG2/CD86/MNDA/CD80/BTK/INPP5D/LST1/LYN/LRRC32/IL2RA/LILRB1	25
BP	GO:0050672	negative regulation of lymphocyte proliferation	25/2112	73/18670	1.927e-07	7.736e-06	5.59e-06	PLA2G2D/XCL1/CTLA4/BMP4/IDO1/DLG5/LILRB2/HLA-G/LGALS9/TNFRSF14/TWSG1/BTN2A2/PTPN6/ERBB2/PDCD1LG2/CD86/MNDA/CD80/BTK/INPP5D/LST1/LYN/LRRC32/IL2RA/LILRB1	25
BP	GO:0006874	cellular calcium ion homeostasis	89/2112	458/18670	1.983e-07	7.912e-06	5.717e-06	CCL5/CXCL13/CXCL9/CCR5/XCL1/LCK/PTPRC/CCR2/LRP6/CORO1A/PLCE1/CXCR4/CCL19/SRI/CACNA2D1/CCL13/ANK2/CCR7/LPAR1/PRKCB/TCIRG1/CD52/ACKR3/JAK2/CD36/CD40/HTR2B/GATA2/CXCL10/PTPN6/FGF2/GPR18/TAC1/PLCG2/CCL21/NMB/BAK1/CCR1/CX3CR1/PLN/CXCR6/AFG3L2/MICU1/MS4A1/TRPC1/HTR2A/CD19/ATP1B1/SMAD3/GPR65/ATP13A3/FPR1/AGTR1/RGN/ATP1A2/CXCL11/PTGFR/SLC8A1/PTGER4/CCL7/P2RY6/APLNR/EDNRB/SLC25A23/HCRTR1/CD38/DDIT3/CCR8/RYR3/RIC3/FPR2/CYBA/LYN/PKD2/GSTO1/GSTM2/S1PR1/PTH1R/TGM2/ITGAV/S1PR4/GPR4/CCRL2/CCL23/EPHX2/P2RY4/CDH5/PML/ATP2A3	89
BP	GO:0007229	integrin-mediated signaling pathway	31/2112	103/18670	2.002e-07	7.934e-06	5.732e-06	ITGB7/PLP1/ITGA4/LAT/EMP2/ITGB1BP1/ITGB2/FERMT2/FGR/ITGBL1/ITGAL/PLEK/PTN/DOCK1/PTPN11/VAV1/ITGA10/SYK/TEC/ITGAX/FERMT1/ADAM10/PRKD1/HCK/FUT8/ITGAV/LIMS2/ISG15/COL16A1/ITGAE/VAV3	31
BP	GO:0070664	negative regulation of leukocyte proliferation	26/2112	78/18670	2.041e-07	8.023e-06	5.797e-06	PLA2G2D/XCL1/CTLA4/TNFAIP3/BMP4/IDO1/DLG5/LILRB2/HLA-G/LGALS9/TNFRSF14/TWSG1/BTN2A2/PTPN6/ERBB2/PDCD1LG2/CD86/MNDA/CD80/BTK/INPP5D/LST1/LYN/LRRC32/IL2RA/LILRB1	26
BP	GO:0032640	tumor necrosis factor production	42/2112	163/18670	2.05e-07	8.023e-06	5.797e-06	PIK3R1/PTPRC/TNFAIP3/CD2/CCR2/IL27RA/IGF1/SLAMF1/RASGRP1/CLU/ZBTB20/CCL19/SASH3/TLR2/ANGPT1/AXL/LGALS9/NOD2/JAK2/CD36/IFIH1/RIPK2/HLA-E/PTPN6/GPR18/CLEC7A/AKAP12/CX3CR1/DDX58/PTPN11/LEP/IFNG/CLEC4A/ADIPOQ/SYK/HSPB1/MAPKAPK2/PTPN22/UBE2J1/CYBA/NOD1/LILRB1	42
BP	GO:0051258	protein polymerization	62/2112	283/18670	2.084e-07	8.104e-06	5.855e-06	WASF3/CORO1A/ADD3/ARPIN/TMOD1/TPPP3/CCR7/COTL1/HCLS1/PFN2/UBE2C/MX2/MSRB2/ICAM1/JAK2/GOLGA2/COBL/WASL/PSTPIP2/TMSB10/FGF13/CCL21/WAS/CDC42EP3/ZNF207/TUBB4A/GAS7/NCKAP1L/GMFG/MAP7D3/VASP/GPX4/ARPC5L/KANK1/LMOD1/MECP2/TERF1/PAK1/MYO1C/FBXO5/CAMSAP2/CTTN/PINK1/MAP1B/FER/CAPZA1/VILL/AP1AR/ANG/CLIP3/TUBG2/HCK/ARPC1A/MX1/ABI2/ACTR3/PFN1/IQGAP2/SPTBN1/GSN/CDH5/ACTR2	62
BP	GO:2000106	regulation of leukocyte apoptotic process	27/2112	83/18670	2.108e-07	8.146e-06	5.886e-06	CCL5/KITLG/CCR5/BMP4/IDO1/PRKCQ/CCL19/IL7R/CCR7/CD74/AXL/HCLS1/CD3G/LGALS9/NOD2/IRF7/ADAM8/ADA/CCL21/CD27/PIK3CD/BTK/AURKB/LYN/MERTK/TP53/LILRB1	27
BP	GO:0051090	regulation of DNA-binding transcription factor activity	85/2112	432/18670	2.134e-07	8.196e-06	5.922e-06	ENPP1/TRAF3/AIM2/XCL1/TNFAIP3/S100A9/LRP6/DDR2/PRKCH/CLU/TRAF1/PRKCQ/SRI/PIM1/MYD88/PPP3CA/NFKB2/PRKCB/TLR2/CD200/HCLS1/ITGB2/AR/NFKBIE/ICAM1/LGALS9/NOD2/MALT1/ADAM8/JAK2/CD36/HDAC4/CD40/PRKD2/ANXA3/RIPK2/DAP/SPHK1/ADORA3/SIK1/TCF7L2/EZH2/CX3CR1/ID3/NFKBIA/CAMK1D/CD40LG/RPS6KA4/DDX58/NFKB1/FZD4/TRIM21/SMAD3/SYK/GFI1/FOSL1/IKBKG/TRIM22/PINK1/BTK/TNFRSF4/IL6/FZD6/FER/ANXA4/TRIM38/DDIT3/RB1/IL18/TRIM26/PRKD1/MBTPS2/NOD1/RWDD1/HIPK2/PKD2/HCK/CFLAR/CAT/FZD2/USP7/MED13/TLR6/IL1B/NLRP3	85
BP	GO:0002573	myeloid leukocyte differentiation	49/2112	204/18670	2.172e-07	8.291e-06	5.99e-06	RELB/KITLG/PIK3R1/SFRP1/LBR/BMP4/GPR183/CCL19/IL15/BATF/INHBA/CCR7/PIR/TLR2/IRF4/CD74/PTPN2/HCLS1/TCIRG1/CBFA2T3/IRF7/LILRB3/GATA2/TFRC/EVI2B/SH3PXD2A/CCR1/LILRB4/PIK3CD/LEF1/CA2/GLO1/ZFP36L1/IFNG/ADIPOQ/PARP1/SPI1/INPP5D/TESC/RB1/GAB2/LYN/CEBPA/FSTL3/SNX10/CD81/TOB2/SBNO2/LILRB1	49
BP	GO:0072503	cellular divalent inorganic cation homeostasis	94/2112	493/18670	2.255e-07	8.553e-06	6.18e-06	CCL5/CXCL13/CXCL9/CCR5/XCL1/LCK/PTPRC/CCR2/S100A9/LRP6/CORO1A/PLCE1/CXCR4/CCL19/SRI/CACNA2D1/CCL13/ANK2/CCR7/LPAR1/PRKCB/TCIRG1/CD52/ACKR3/JAK2/CD36/CD40/HTR2B/GATA2/CXCL10/PTPN6/FGF2/GPR18/TAC1/PLCG2/CCL21/NMB/SLC39A8/BAK1/CCR1/CX3CR1/PLN/CXCR6/AFG3L2/MICU1/MS4A1/TRPC1/HTR2A/CD19/ATP1B1/SMAD3/GPR65/ATP13A3/FPR1/AGTR1/RGN/ATP1A2/CXCL11/PTGFR/SLC8A1/PTGER4/CCL7/P2RY6/APLNR/EDNRB/SLC25A23/HCRTR1/SLC39A6/CD38/DDIT3/CCR8/RYR3/RIC3/FPR2/CYBA/LYN/PKD2/GSTO1/SLC39A7/GSTM2/S1PR1/PTH1R/TGM2/ITGAV/S1PR4/GPR4/CCRL2/CCL23/MT1X/EPHX2/P2RY4/CDH5/PML/ATP2A3	94
BP	GO:0048015	phosphatidylinositol-mediated signaling	45/2112	181/18670	2.346e-07	8.845e-06	6.391e-06	CCL5/PLEKHA1/PIK3R1/IGF1/RASGRP1/PLCE1/SOX9/SEMA4D/NTRK2/ANGPT1/HCLS1/JAK2/PDGFD/PIP4K2B/HTR2B/FGR/EGFR/BTN2A2/PTPN6/DCN/CEP55/PLCG2/CD160/ERBB2/HGF/PPP1R16B/PIK3CD/HTR2A/PTPN13/FBXL2/MYOC/LEP/ZFP36L1/PIK3CA/FLT3/PIP4K2A/IL18/GAB2/LYN/KDR/CAT/NCF1/NPR3/PRR5L/GSN	45
BP	GO:0043367	CD4-positive, alpha-beta T cell differentiation	25/2112	74/18670	2.599e-07	9.74e-06	7.038e-06	RELB/PLA2G2D/RUNX3/SEMA4A/GPR183/CCL19/BATF/SASH3/IRF4/IL4R/LGALS9/MALT1/SOCS1/RIPK2/TBX21/NCKAP1L/CD86/CD83/LEF1/IFNG/PTGER4/CD80/IL6/IL18/NLRP3	25
BP	GO:0045807	positive regulation of endocytosis	40/2112	153/18670	2.617e-07	9.746e-06	7.042e-06	IL2RG/PTPRC/IL15RA/CLU/IL2RB/CCL19/IL15/PPP3CA/SIRPG/ANGPT1/AXL/TBC1D5/CD36/ITSN1/WASL/GATA2/DNM1/CLEC7A/SELE/PLCG2/CCL21/MAGI2/NLGN1/CAMK1D/NCKAP1L/SOD1/RAB27A/DOCK2/IFNG/SYK/HFE/FPR2/CYBA/CLIP3/MERTK/ITGAV/CCL2/IL1B/PTX3/AHI1	40
BP	GO:0051897	positive regulation of protein kinase B signaling	44/2112	176/18670	2.689e-07	9.957e-06	7.194e-06	KITLG/LCK/PIK3R1/IGFBP5/BTC/RAC2/FGF18/CCL19/TRAT1/AKR1C3/CCR7/ANGPT1/FGF7/AXL/HCLS1/ITGB1BP1/ADAM8/ITSN1/EGFR/HBEGF/FGF2/CCL21/ERBB2/HGF/TCF7L2/CX3CR1/NOX4/PIK3CD/CD86/CD19/ICOS/PTPN11/VAV1/MFHAS1/KL/MYOC/LEP/RHOG/PIK3CA/HSP90AB1/CD80/FGF9/PINK1/IL18	44
BP	GO:0051783	regulation of nuclear division	46/2112	188/18670	2.854e-07	1.05e-05	7.589e-06	BMP4/CDKN1C/IGF1/TACC3/BTC/PTTG1/PTTG3P/MKI67/BUB1/NFE2L1/NUSAP1/UBE2C/NDC80/MAD2L1/PLK1/BORA/CDC14B/UBE2B/KIF11/SPHK1/TPR/MAP9/DLGAP5/ZNF207/STAG2/BUB1B/LRP5/DAZL/NEK2/TOM1L1/ATRX/CCNB1/FBXO5/NIPBL/CEP85/CENPF/TTK/CHMP2B/AURKB/RB1/CDC20/KIF20B/TRIP13/AURKA/IL1B/CHMP1B	46
BP	GO:0019722	calcium-mediated signaling	51/2112	218/18670	2.989e-07	1.093e-05	7.901e-06	CCR5/CD3E/PTPRC/CCR2/GBP1/IGF1/PLCE1/CXCR4/SRI/TRAT1/LAT/ANK2/MCTP1/PPP3CA/CCR7/ACKR3/HDAC4/HTR2B/EGFR/ADA/SPHK1/ZAP70/CXCL8/SELE/PLCG2/TMEM100/PLEK/CCR1/CX3CR1/PLN/CXCR6/SGCD/ATP1B1/AGTR1/RGN/ATP1A2/PTGFR/SLC8A1/SYK/P2RY6/EDNRB/BTK/CCR8/FPR2/KDR/PKD2/GSTO1/GSTM2/CAMTA1/HINT1/CCRL2	51
BP	GO:0110053	regulation of actin filament organization	58/2112	261/18670	3.08e-07	1.12e-05	8.093e-06	PIK3R1/SFRP1/LIMCH1/CORO1A/ADD3/ARPIN/TMOD1/CCR7/LPAR1/COTL1/HCLS1/PFN2/ITGB1BP1/ICAM1/WASL/TMSB10/DLC1/TAC1/CCL21/WAS/CDC42EP3/PLEK/NOX4/NCKAP1L/GMFG/ARHGEF10/DSTN/SMAD3/VASP/ARPC5L/CORO2B/GPR65/MYOC/KANK1/LMOD1/PPM1F/PTGER4/PAK1/MYO1C/TGFB3/CTTN/FER/CFL1/CAPZA1/VILL/AP1AR/HCK/ARPC1A/WASF2/WDR1/S1PR1/ABI2/ACTR3/PFN1/IQGAP2/SPTBN1/GSN/ACTR2	58
BP	GO:0032615	interleukin-12 production	21/2112	56/18670	3.175e-07	1.148e-05	8.295e-06	IRF1/SLAMF1/TLR8/IDO1/CCL19/IRF8/CCR7/TLR2/LTB/HLA-G/LGALS9/CD36/CD40/RIPK2/CLEC7A/CD40LG/NFKB1/LEP/IFNG/SYK/LILRB1	21
BP	GO:0002821	positive regulation of adaptive immune response	31/2112	105/18670	3.225e-07	1.159e-05	8.375e-06	XCL1/PTPRC/CCR2/IL27RA/HLA-F/HLA-A/PRKCQ/CCL19/HLA-C/SASH3/HLA-G/MALT1/CD40/RIPK2/TFRC/HLA-E/ADA/HLA-B/CD226/TBX21/SKAP1/IL6ST/FAM49B/CD80/BTK/IL6/IL18/CD81/IL1R1/IL1B/NLRP3	31
BP	GO:0002709	regulation of T cell mediated immunity	24/2112	70/18670	3.288e-07	1.162e-05	8.397e-06	XCL1/PTPRC/CCR2/HLA-F/TNFRSF1B/HLA-A/IL7R/HLA-C/SASH3/HLA-G/MALT1/HLA-E/HLA-B/WAS/TBX21/FAM49B/HFE/IL6/IL18/CD81/IL1R1/IL1B/LILRB1/NLRP3	24
BP	GO:0051480	regulation of cytosolic calcium ion concentration	73/2112	357/18670	3.296e-07	1.162e-05	8.397e-06	CXCL13/CXCL9/CCR5/XCL1/LCK/PTPRC/CCR2/LRP6/CORO1A/PLCE1/CXCR4/CCL19/SRI/CACNA2D1/ANK2/CCR7/LPAR1/CD52/ACKR3/JAK2/CD36/HTR2B/GATA2/CXCL10/PTPN6/FGF2/GPR18/TAC1/PLCG2/CCL21/NMB/BAK1/CCR1/CX3CR1/PLN/CXCR6/MS4A1/TRPC1/HTR2A/CD19/SMAD3/GPR65/FPR1/AGTR1/ATP1A2/CXCL11/PTGFR/SLC8A1/PTGER4/P2RY6/APLNR/EDNRB/HCRTR1/CD38/DDIT3/CCR8/RYR3/RIC3/FPR2/CYBA/LYN/PKD2/GSTO1/GSTM2/S1PR1/PTH1R/TGM2/ITGAV/S1PR4/GPR4/CCRL2/P2RY4/PML	73
BP	GO:0042552	myelination	36/2112	132/18670	3.345e-07	1.162e-05	8.397e-06	WASF3/TYMP/CLU/TNFRSF1B/CST7/CXCR4/PLP1/NTRK2/SKI/PARD3/ANK2/LPAR1/TLR2/JAM3/CTSC/DAG1/PMP22/ASPA/ERBB2/HGF/FA2H/PTN/AFG3L2/SOD1/ARHGEF10/ZPR1/ADAM22/ZSCAN26/CD9/MYOC/ITGAX/MPP5/TENM4/SH3TC2/RNF10/MTMR2	36
BP	GO:0032735	positive regulation of interleukin-12 production	16/2112	35/18670	3.346e-07	1.162e-05	8.397e-06	IRF1/IDO1/CCL19/IRF8/CCR7/TLR2/LTB/HLA-G/LGALS9/CD36/CD40/RIPK2/CLEC7A/CD40LG/IFNG/SYK	16
BP	GO:0050856	regulation of T cell receptor signaling pathway	17/2112	39/18670	3.357e-07	1.162e-05	8.397e-06	LCK/GBP1/PVRIG/TRAT1/CCR7/PTPN2/MALT1/PRKD2/BTN2A2/ADA/PTPN6/CD160/CD226/LILRB4/PTPN22/CD81/UBASH3A	17
BP	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	54/2112	237/18670	3.364e-07	1.162e-05	8.397e-06	TNFAIP3/BIRC3/STAT1/CCL19/SECTM1/MYD88/CCR7/LPAR1/PRKCB/ANGPT1/CD74/TNFSF10/LGALS9/NOD2/MALT1/WLS/TNIP2/CD36/APOL3/CD40/HTR2B/RIPK2/TSPAN6/CASP10/CCL21/S100A13/RHOH/CX3CR1/CASP1/ZMYND11/PLK2/BRD4/ECT2/DDX1/ADIPOQ/IKBKG/HSPB1/TRIM22/TNIP3/PINK1/AKAP13/TRIM38/IFIT5/IL1RN/PRKD1/NOD1/NDFIP1/CFLAR/TGM2/CANT1/USP10/PIM2/TLR6/IL1B	54
BP	GO:0048002	antigen processing and presentation of peptide antigen	46/2112	189/18670	3.364e-07	1.162e-05	8.397e-06	PSMB9/TAP1/TAPBP/PSMB8/HLA-F/HLA-A/PSMB10/CTSF/TAP2/HLA-C/CD74/HLA-G/DYNC1LI2/CD36/CTSL/PSME1/ERAP2/HLA-E/KIF11/KIF15/HLA-DRA/KIF3B/HLA-DPB1/HLA-B/SEC31A/FCGR1B/NCF4/KIF2C/KIF4A/DYNC1I1/HLA-DMA/HLA-DMB/RACGAP1/CLEC4A/TAPBPL/HLA-DQB2/DCTN6/IKBKG/HFE/HLA-DPA1/CAPZA1/OSBPL1A/CYBA/NCF1/ITGAV/KIF23	46
BP	GO:0002702	positive regulation of production of molecular mediator of immune response	29/2112	95/18670	3.516e-07	1.208e-05	8.725e-06	XCL1/PTPRC/HLA-F/SASH3/CD74/IL4R/HLA-G/NOD2/MALT1/CD36/CD40/TNFRSF14/TFRC/HLA-E/CD160/CD226/TBX21/DDX58/RBP4/DDX1/STX4/TNFRSF4/IL6/IL18/CD81/IL1R1/IL1B/LILRB1/NLRP3	29
BP	GO:0051092	positive regulation of NF-kappaB transcription factor activity	39/2112	149/18670	3.556e-07	1.215e-05	8.777e-06	AIM2/S100A9/PRKCH/CLU/TRAF1/PRKCQ/MYD88/NFKB2/PRKCB/TLR2/ITGB2/AR/ICAM1/LGALS9/NOD2/MALT1/ADAM8/CD36/CD40/PRKD2/RIPK2/SPHK1/CX3CR1/CD40LG/RPS6KA4/NFKB1/IKBKG/TRIM22/BTK/FER/TRIM38/IL18/PRKD1/NOD1/CFLAR/CAT/TLR6/IL1B/NLRP3	39
BP	GO:0045778	positive regulation of ossification	28/2112	90/18670	3.601e-07	1.223e-05	8.838e-06	NELL1/BMP4/IGF1/DDR2/ZHX3/ZBTB16/GLI3/BMPR1A/TAC1/HGF/PTN/LRP5/TP63/SMAD3/KL/IL6ST/SLC8A1/TFAP2A/ACVR1/FBXO5/TGFB3/NIPBL/IL6/PRKD1/CEBPA/TOB2/ATRAID/ISG15	28
BP	GO:0030100	regulation of endocytosis	61/2112	281/18670	3.643e-07	1.231e-05	8.892e-06	IL2RG/PTPRC/EPHA3/CSK/IL15RA/CLU/IL2RB/CCL19/IL15/MCTP1/PPP3CA/SIRPG/TLR2/ANGPT1/AXL/TBC1D5/USP46/DYSF/CD36/ITSN1/WASL/GATA2/FGR/DNM1/SPHK1/CLEC7A/SELE/PLCG2/CCL21/MAGI2/NLGN1/EHD4/CAMK1D/NCKAP1L/SOD1/LRPAP1/RAB20/RAB27A/DOCK2/IFNG/STON1/ADIPOQ/ATG3/SYK/HFE/NR1H3/FPR2/CYBA/PRKD1/CLIP3/HCK/MERTK/ATXN2/MTMR2/ITGAV/CCL2/SH3GL3/IL1B/PTX3/LILRB1/AHI1	61
BP	GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	22/2112	61/18670	3.701e-07	1.243e-05	8.985e-06	XCL1/RUNX3/PRKCQ/CCL19/SASH3/IRF4/IL4R/LGALS9/MALT1/SOCS1/TWSG1/RIPK2/CD160/TBX21/NCKAP1L/CD86/CD83/IFNG/CD80/IL18/CD81/NLRP3	22
BP	GO:0051896	regulation of protein kinase B signaling	55/2112	244/18670	3.804e-07	1.271e-05	9.186e-06	KITLG/PLEKHA1/LCK/PIK3R1/IGFBP5/BTC/RAC2/FGF18/CCL19/NTRK2/TRAT1/AKR1C3/CCR7/ANGPT1/FGF7/AXL/HCLS1/ITGB1BP1/HLA-G/ADAM8/ITSN1/EGFR/BTN2A2/HBEGF/DAG1/FGF2/CCL21/ERBB2/HGF/MAGI2/TCF7L2/CX3CR1/NOX4/PIK3CD/RRAS/CD86/CD19/ICOS/PTPN11/VAV1/MFHAS1/KL/MYOC/LEP/RHOG/PIK3CA/HSP90AB1/PHLPP1/CD80/FGF9/PINK1/RCN3/DDIT3/IL18/SH2B3	55
BP	GO:0007249	I-kappaB kinase/NF-kappaB signaling	59/2112	269/18670	3.908e-07	1.299e-05	9.385e-06	RELB/TNFAIP3/BIRC3/TLR8/STAT1/CCL19/SECTM1/MYD88/CCR7/LPAR1/PRKCB/TLR2/ANGPT1/CD74/TNFSF10/LGALS9/NOD2/MALT1/WLS/TNIP2/CD36/APOL3/CD40/HTR2B/RIPK2/TSPAN6/CASP10/CCL21/S100A13/RHOH/CX3CR1/NFKBIA/CASP1/ZMYND11/PLK2/BRD4/ECT2/DDX1/ADIPOQ/IKBKG/HSPB1/TRIM22/TNIP3/PINK1/BTK/AKAP13/TRIM38/IFIT5/IL1RN/PRKD1/NOD1/NDFIP1/CFLAR/TGM2/CANT1/USP10/PIM2/TLR6/IL1B	59
BP	GO:0001776	leukocyte homeostasis	27/2112	86/18670	4.727e-07	1.556e-05	1.124e-05	KITLG/TNFAIP3/CCR2/CORO1A/GPR183/DOCK10/SH2B2/LAT/JAM3/CD74/AXL/CCNB2/TCIRG1/LGALS9/ADA/BAK1/NCKAP1L/PIK3CD/PMAIP1/FLT3/IL6/CXCL6/LYN/SH2B3/MERTK/IL2RA/TNFRSF17	27
BP	GO:0008154	actin polymerization or depolymerization	49/2112	209/18670	4.731e-07	1.556e-05	1.124e-05	WASF3/CORO1A/ADD3/ARPIN/TMOD1/CCR7/COTL1/HCLS1/PFN2/MSRB2/ICAM1/JAK2/COBL/WASL/PSTPIP2/TMSB10/CCL21/WAS/CDC42EP3/PLEK/ENAH/GAS7/NCKAP1L/GMFG/CAP2/DSTN/VASP/ARPC5L/KANK1/LMOD1/MICAL1/MYO1C/CTTN/FER/CFL1/CAPZA1/VILL/AP1AR/ANG/HCK/ARPC1A/WDR1/ABI2/ACTR3/PFN1/IQGAP2/SPTBN1/GSN/ACTR2	49
BP	GO:0007272	ensheathment of neurons	36/2112	134/18670	4.994e-07	1.625e-05	1.174e-05	WASF3/TYMP/CLU/TNFRSF1B/CST7/CXCR4/PLP1/NTRK2/SKI/PARD3/ANK2/LPAR1/TLR2/JAM3/CTSC/DAG1/PMP22/ASPA/ERBB2/HGF/FA2H/PTN/AFG3L2/SOD1/ARHGEF10/ZPR1/ADAM22/ZSCAN26/CD9/MYOC/ITGAX/MPP5/TENM4/SH3TC2/RNF10/MTMR2	36
BP	GO:0008366	axon ensheathment	36/2112	134/18670	4.994e-07	1.625e-05	1.174e-05	WASF3/TYMP/CLU/TNFRSF1B/CST7/CXCR4/PLP1/NTRK2/SKI/PARD3/ANK2/LPAR1/TLR2/JAM3/CTSC/DAG1/PMP22/ASPA/ERBB2/HGF/FA2H/PTN/AFG3L2/SOD1/ARHGEF10/ZPR1/ADAM22/ZSCAN26/CD9/MYOC/ITGAX/MPP5/TENM4/SH3TC2/RNF10/MTMR2	36
BP	GO:0032623	interleukin-2 production	22/2112	62/18670	5.126e-07	1.659e-05	1.199e-05	XCL1/CD3E/PTPRC/TNFAIP3/CCR2/GBP1/CD247/PRKCQ/SASH3/IRF4/MALT1/PRKD2/RIPK2/CLEC7A/TBX21/CD86/CD83/PNP/CD80/IL18/SPTBN1/IL1B	22
BP	GO:0000070	mitotic sister chromatid segregation	39/2112	151/18670	5.158e-07	1.661e-05	1.2e-05	TACC3/PTTG1/PTTG3P/BUB1/NUSAP1/NCAPD2/NDC80/MAD2L1/PLK1/CDCA8/NCAPH/KIF18B/NCAPG/TPR/DLGAP5/ZNF207/BUB1B/KIF2C/KIF4A/PRC1/NEK2/ATRX/RACGAP1/ZWINT/CCNB1/FBXO5/NIPBL/CENPF/TTK/CHMP2B/AURKB/RB1/CDC20/TUBG2/SMC4/TRIP13/KIFC1/CHMP1B/KIF23	39
BP	GO:0002367	cytokine production involved in immune response	30/2112	102/18670	5.44e-07	1.73e-05	1.25e-05	XCL1/CCR2/HLA-F/TNFRSF1B/SASH3/TLR2/ANGPT1/CD74/HLA-G/NOD2/MALT1/CD36/CD96/TNFRSF14/HLA-E/CD160/CD226/TBX21/DDX58/DDX1/HFE/TGFB3/BTK/IL6/IL18/CD81/IL1R1/IL1B/LILRB1/NLRP3	30
BP	GO:2000379	positive regulation of reactive oxygen species metabolic process	30/2112	102/18670	5.44e-07	1.73e-05	1.25e-05	PID1/CLU/AKR1C3/HBB/ITGB2/ICAM1/JAK2/CD36/HDAC4/EGFR/DDAH2/CLEC7A/NOX4/SOD1/SMAD3/RAB27A/LEP/AGTR1/IFNG/RGN/HSP90AB1/SYK/FOXO3/FPR2/CYBA/PKD2/TP53/TLR6/IL1B/PTX3	30
BP	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	46/2112	192/18670	5.456e-07	1.73e-05	1.25e-05	CCL5/KITLG/CD3E/PTPRC/CRLF1/IGF1/IL15/SEMA4D/NTRK2/ANGPT1/FGF7/CD74/HCLS1/ICAM1/JAK2/CD36/CD40/TNFRSF14/RIPK2/HBEGF/THBS4/CSPG4/GHR/HGF/EHD4/NOX4/HTR2A/EFNA5/PTPN11/LEP/IL6ST/IFNG/PECAM1/FLT3/ADIPOQ/SYK/CD80/TEC/ACVR1/CTF1/IL6/IL18/LYN/CD81/NCF1/TP53	46
BP	GO:1902905	positive regulation of supramolecular fiber organization	48/2112	204/18670	5.514e-07	1.739e-05	1.257e-05	SFRP1/LIMCH1/CORO1A/CLU/ARPIN/CCR7/LPAR1/PFN2/ITGB1BP1/ICAM1/WASL/TAC1/CCL21/WAS/CDC42EP3/PLEK/NOX4/NCKAP1L/GMFG/ARHGEF10/DSTN/SMAD3/VASP/ARPC5L/GPR65/MYOC/LMOD1/MECP2/PPM1F/TERF1/PAK1/MYO1C/TGFB3/CTTN/MAP1B/FER/CFL1/AP1AR/RB1/HCK/ARPC1A/WDR1/ABI2/ACTR3/PFN1/IQGAP2/GSN/ACTR2	48
BP	GO:0042113	B cell activation	65/2112	310/18670	5.702e-07	1.79e-05	1.293e-05	SLAMF8/TRBC1/PIK3R1/SFRP1/PTPRC/CTLA4/TNFAIP3/IL27RA/GPR183/IL7R/ITGA4/BATF/DOCK10/INHBA/PRKCB/SASH3/CD74/PTPN2/TCIRG1/NOD2/MALT1/TNIP2/SAMSN1/HDAC4/CD40/TFRC/ADA/PTPN6/ZAP70/IGHM/IGLL5/PLCG2/BAK1/TBX21/CD27/CD40LG/NCKAP1L/PIK3CD/MS4A1/CD19/LEF1/ZFP36L1/MNDA/IGLC1/FLT3/SYK/ICOSLG/BTK/TNFRSF4/IL6/TPD52/CD38/IGHG1/INPP5D/CD180/CD320/LYN/CD81/ERCC1/ZFP36L2/THOC1/TP53/IFNA1/VAV3/CR2	65
BP	GO:0032609	interferon-gamma production	32/2112	113/18670	5.932e-07	1.852e-05	1.338e-05	ITK/XCL1/CD3E/CD2/CCR2/IL27RA/RASGRP1/TLR8/IRF8/INHBA/CCR7/SASH3/AXL/TCIRG1/LGALS9/CD96/RIPK2/CLEC7A/HLA-DPB1/CD160/TXK/CD226/PDCD1LG2/FAM49B/BTN3A1/PTPN22/HLA-DPA1/IL18/IL1R1/ISG15/IL1B/LILRB1	32
BP	GO:0048285	organelle fission	86/2112	449/18670	6.011e-07	1.868e-05	1.349e-05	BMP4/CDKN1C/IGF1/TACC3/BTC/ASPM/PTTG1/PTTG3P/MKI67/BUB1/NFE2L1/NUSAP1/SIRT7/UBE2C/NCAPD2/MX2/NDC80/MAD2L1/GOLGA2/PLK1/TPX2/BORA/CDC14B/UBE2B/KIF11/CDCA8/NCAPH/KIF18B/SPHK1/DCN/CDC25B/RPL24/KIF3B/NCAPG/TPR/MAP9/DLGAP5/ZNF207/STAG2/BUB1B/KIF2C/LRP5/KIF4A/ARHGEF10/DAZL/TOP2A/PRC1/NEK2/TOM1L1/MYBL1/RMI1/ATRX/CKS2/RACGAP1/ZWINT/STAG3/CCNB1/TMEM135/TERF1/FBXO5/PEX19/NIPBL/CEP85/PINK1/CENPF/REC8/TTK/CHMP2B/AURKB/RB1/CDC20/TUBG2/KDR/KIF20B/MX1/SMC4/ACTR3/TRIP13/CCNE2/AURKA/KIFC1/INF2/IL1B/ACTR2/CHMP1B/KIF23	86
BP	GO:0046777	protein autophosphorylation	53/2112	235/18670	6.043e-07	1.868e-05	1.35e-05	ENPP1/ITK/LCK/PTPRC/STK10/DDR2/CSK/PIM1/NTRK2/VRK2/MAP3K11/VRK1/JAK2/PDGFD/PRKD2/FGR/TRIM24/EGFR/STK17B/MELK/MAP4K1/PASK/ZAP70/ERBB2/SIK1/TXK/EPHB1/NEK2/TOM1L1/FLT3/PAK1/ADIPOQ/SYK/TEC/FRK/PINK1/BTK/MAPKAPK2/TTK/FER/NLK/AURKB/PRKD1/LYN/GFRA2/KDR/SLA/HCK/MYO3A/PIM2/MVP/AURKA/PRKG2	53
BP	GO:0002478	antigen processing and presentation of exogenous peptide antigen	43/2112	175/18670	6.088e-07	1.873e-05	1.353e-05	PSMB9/TAP1/TAPBP/PSMB8/HLA-F/HLA-A/PSMB10/CTSF/TAP2/HLA-C/CD74/HLA-G/DYNC1LI2/CD36/CTSL/PSME1/HLA-E/KIF11/KIF15/HLA-DRA/KIF3B/HLA-DPB1/HLA-B/SEC31A/FCGR1B/NCF4/KIF2C/KIF4A/DYNC1I1/HLA-DMA/HLA-DMB/RACGAP1/CLEC4A/HLA-DQB2/DCTN6/IKBKG/HLA-DPA1/CAPZA1/OSBPL1A/CYBA/NCF1/ITGAV/KIF23	43
BP	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling	34/2112	124/18670	6.13e-07	1.876e-05	1.356e-05	CCL5/PIK3R1/IGF1/RASGRP1/SOX9/SEMA4D/NTRK2/ANGPT1/HCLS1/JAK2/PDGFD/PIP4K2B/FGR/EGFR/BTN2A2/PTPN6/DCN/CEP55/HGF/PPP1R16B/PIK3CD/PTPN13/FBXL2/MYOC/LEP/PIK3CA/FLT3/PIP4K2A/IL18/LYN/KDR/CAT/NCF1/PRR5L	34
BP	GO:0007051	spindle organization	42/2112	170/18670	7.006e-07	2.134e-05	1.542e-05	TACC3/ASPM/MAPRE2/MAP4/NDC80/EML1/GOLGA2/PLK1/TPX2/BORA/KIF11/KIF3B/TPR/TACC1/MAP9/ZNF207/STAG2/KIF4A/NEK7/ARHGEF10/PRC1/NEK2/ATRX/PLK2/RACGAP1/VCP/SPC25/TACC2/CCNB1/MECP2/FBXO5/TTK/CHMP2B/AURKB/CEP63/CDC20/TUBG2/AURKA/KIFC1/CHMP1B/STIL/KIF23	42
BP	GO:0031341	regulation of cell killing	29/2112	98/18670	7.265e-07	2.202e-05	1.591e-05	XCL1/PTPRC/PRF1/RASGRP1/HLA-F/HLA-A/IL7R/HLA-C/HLA-G/ICAM1/LGALS9/MICB/CRTAM/HLA-E/CLEC7A/SH2D1A/CD160/HLA-B/CD226/CADM1/VAV1/LEP/IFNG/FAM49B/HSP90AB1/KRT6A/SYK/CXCL6/LILRB1	29
BP	GO:0002688	regulation of leukocyte chemotaxis	32/2112	114/18670	7.362e-07	2.22e-05	1.604e-05	CCL5/CXCL13/SLAMF8/XCL1/CCR2/RAC2/CCL19/CCR7/JAM3/CD74/LGALS9/DYSF/GPSM3/CXCL10/GPR18/THBS4/CXCL8/CCL21/CCR1/CAMK1D/PTN/NCKAP1L/NBL1/CCL7/IL6/FPR2/ADAM10/VEGFB/MTUS1/LYN/CCL2/PLA2G7	32
BP	GO:0033627	cell adhesion mediated by integrin	23/2112	68/18670	7.58e-07	2.275e-05	1.644e-05	CCL5/CXCL13/CD3E/LPXN/ITGB7/ITGA4/ITGB1BP1/ITGB2/ICAM1/ADA/PTPN6/ITGBL1/CCL21/NCKAP1L/SKAP1/PTPN11/SYK/TESC/FERMT1/LYN/PDE3B/ITGAV/COL16A1	23
BP	GO:0032655	regulation of interleukin-12 production	20/2112	54/18670	7.628e-07	2.278e-05	1.646e-05	IRF1/SLAMF1/TLR8/IDO1/CCL19/IRF8/CCR7/TLR2/LTB/HLA-G/LGALS9/CD36/CD40/RIPK2/CLEC7A/CD40LG/NFKB1/IFNG/SYK/LILRB1	20
BP	GO:0051222	positive regulation of protein transport	81/2112	418/18670	7.819e-07	2.324e-05	1.679e-05	AIM2/PIK3R1/CD2/IGF1/ZIC1/RASGRP1/TLR8/RAC2/MYH10/FCN1/CCL19/SRI/GLI3/OXCT1/ABCG1/TLR2/HCLS1/ITGB1BP1/ITGB2/IL4R/LGALS9/NOD2/ADAM8/WLS/JAK2/IFIH1/HTR2B/TNFRSF14/RIPK2/FGR/CRTAM/EGFR/HLA-E/TM7SF3/MPC2/TPR/CD160/CLEC4E/ERBB2/AKAP12/TCF7L2/CADM1/ZPR1/DDX58/CASP1/SMAD3/EDEM1/RBP4/ECT2/LEP/IFNG/OR51E2/PTGER4/PAK1/MYO1C/STX4/SYK/ZFAND1/VAMP2/TGFB3/PINK1/TNFRSF4/IL6/PTPN22/CD38/SYBU/FERMT1/ANG/PANX1/HSPA1L/KIF20B/CD81/EDEM2/PRR5L/TP53/SPTBN1/IL1B/MMP12/XPO4/GPR27/NLRP3	81
BP	GO:0070372	regulation of ERK1 and ERK2 cascade	63/2112	300/18670	8.007e-07	2.369e-05	1.711e-05	CCL5/XCL1/PTPRC/BMP4/GBP1/SLAMF1/RASGRP1/CSK/TIMP3/LMO3/FGF18/GPR183/CCL19/CCL13/CCR7/ANGPT1/CD74/PTPN2/ITGB1BP1/ICAM1/LGALS9/ACKR3/NOD2/CD36/PDGFD/PRKD2/HTR2B/RIPK2/EGFR/BTN2A2/PTPN6/FGF2/CCL21/ERBB2/AKAP12/CCR1/EPHB1/NOX4/CCL18/RRAS/HTR2A/PTPN11/MFHAS1/NOTCH1/FLT3/CCL7/ADIPOQ/SYK/P2RY6/HCRTR1/PTPN22/DUSP6/FPR2/FBLN1/LYN/NOD1/KDR/CFLAR/CCL17/CCL2/NDRG2/CCL23/IL1B	63
BP	GO:1902903	regulation of supramolecular fiber organization	71/2112	352/18670	8.12e-07	2.391e-05	1.727e-05	PIK3R1/SFRP1/LIMCH1/CORO1A/CLU/ADD3/ARPIN/TMOD1/CCR7/LPAR1/COTL1/HCLS1/PFN2/ITGB1BP1/ICAM1/CRYAB/WASL/TMSB10/CKAP2/DLC1/TAC1/FGF13/CCL21/WAS/CDC42EP3/PLEK/TUBB4A/NOX4/NCKAP1L/GMFG/ARHGEF10/DSTN/SMAD3/VASP/ARPC5L/CORO2B/GPR65/MYOC/KANK1/LMOD1/MECP2/PPM1F/PTGER4/TERF1/PAK1/MYO1C/CAMSAP2/TGFB3/CTTN/AKAP13/MAP1B/FER/CFL1/CAPZA1/VILL/AP1AR/RB1/CLIP3/HCK/ARPC1A/WASF2/WDR1/S1PR1/ABI2/ACTR3/PFN1/IQGAP2/SPTBN1/GSN/CDH5/ACTR2	71
BP	GO:0070555	response to interleukin-1	48/2112	207/18670	8.671e-07	2.541e-05	1.836e-05	CCL5/PSMB9/XCL1/SFRP1/GBP1/PSMB8/GBP2/PSMB10/CCL19/SOX9/MYD88/VRK2/CCL13/SKP1/ICAM1/LGALS9/NOD2/TNIP2/HDAC4/MAP3K8/PSME1/RIPK2/CXCL8/SELE/CCL21/AKAP12/PCK1/NFKBIA/MAPK13/CCL18/RPS6KA4/NFKB1/HYAL1/KMO/CCL7/IKBKG/IL6/CD38/CYBA/TFPI/IL1RN/NOD1/CCL17/USP10/CCL2/CCL23/IL1R1/IL1B	48
BP	GO:0019883	antigen processing and presentation of endogenous antigen	12/2112	22/18670	9.253e-07	2.699e-05	1.95e-05	TAP1/TAPBP/HLA-F/HLA-A/TAP2/HLA-C/CD74/HLA-G/ERAP2/HLA-E/HLA-B/HFE	12
BP	GO:0002228	natural killer cell mediated immunity	22/2112	64/18670	9.589e-07	2.783e-05	2.011e-05	CORO1A/RASGRP1/HLA-F/GZMB/HLA-G/LGALS9/CD96/MICB/CRTAM/HLA-E/PTPN6/SH2D1A/CD160/CD226/KLRD1/CADM1/RAB27A/VAV1/LEP/IL18/SLAMF7/LILRB1	22
BP	GO:0046718	viral entry into host cell	33/2112	121/18670	1.018e-06	2.942e-05	2.126e-05	CCR5/SLAMF1/ITGB7/CXCR4/FCN1/CD74/AXL/ICAM1/LGALS9/TNFRSF14/TFRC/EGFR/DAG1/NPC1/CR1/CDK1/CD86/HTR2A/CTSB/TRIM21/HYAL1/CD80/TNFRSF4/SCARB2/ANPEP/SELPLG/TRIM38/TRIM26/CD81/ITGAV/GSN/CR2/PTX3	33
BP	GO:0033002	muscle cell proliferation	53/2112	239/18670	1.05e-06	3.018e-05	2.181e-05	CCL5/TNFAIP3/BMP4/IGFBP5/IGF1/STAT1/IL15/OGN/PIM1/FOXC1/MEIS1/ANGPT1/ABCC4/ZFPM2/SIX1/BMPR1A/JAK2/PDGFD/HDAC4/YAP1/AKR1B1/EGFR/HBEGF/FGF2/TGFBR3/PDE1A/CDK1/KCNK2/TCF7L2/EPHB1/DNMT1/RBP4/NOTCH1/IFNG/CCNB1/HEY2/PAK1/ADIPOQ/P2RY6/FGF9/TGFB3/IL6/PRKG1/JARID2/CYBA/IL18/ANG/TENM4/CFLAR/NPR3/S1PR1/TGM2/NDRG2	53
BP	GO:0001818	negative regulation of cytokine production	62/2112	296/18670	1.07e-06	3.054e-05	2.206e-05	RELB/XCL1/PTPRC/TNFAIP3/GBP1/IL27RA/IGF1/SLAMF1/CSK/TLR8/IDO1/HLA-F/INHBA/CD200/ANGPT1/AXL/UBE2L6/LGALS9/NMI/IFIH1/CD96/TWSG1/BTN2A2/SRGN/PTPN6/GPR18/HGF/TBX21/PDCD1LG2/CX3CR1/NCKAP1L/C5orf30/RPS6KA4/DDX58/PTPRS/NFKB1/CD83/LEF1/HERC5/IFNG/CLEC4A/PTGER4/HSP90AB1/ADIPOQ/HFE/TGFB3/SERPINB1/BTK/TNFRSF4/IL6/PTPN22/ANXA4/INPP5D/PPP1R11/MERTK/LRRC32/NDRG2/ISG15/TLR6/PML/LILRB1/NLRP3	62
BP	GO:0002886	regulation of myeloid leukocyte mediated immunity	20/2112	55/18670	1.072e-06	3.054e-05	2.206e-05	CCR2/RAC2/ITGB2/IL4R/LGALS9/GATA2/FGR/HLA-E/IL13RA2/DDX58/STXBP2/DDX1/STX4/SYK/STXBP1/BTK/FER/CXCL6/GAB2/LYN	20
BP	GO:0042063	gliogenesis	61/2112	290/18670	1.124e-06	3.188e-05	2.303e-05	WASF3/CDKN2C/CCR2/PRKCH/PENK/CSK/CLU/TNFRSF1B/CXCR4/NDN/GPR183/PLP1/SOX9/GLI3/NTRK2/SKI/PARD3/LPAR1/ZNF365/NFE2L1/TLR2/LAMA2/MXRA8/EGFR/DAG1/ETV5/NFIB/IDH2/CSPG4/ASPA/ERBB2/CDK1/FA2H/EZH2/CX3CR1/SOX2/PTN/CDH2/SOD1/ARHGEF10/ADAM22/LEF1/PTPN11/DAAM2/CD9/NOTCH1/MYOC/IL6ST/IFNG/IL6/FPR2/LYN/MPP5/TENM4/WDR1/SH3TC2/RNF10/CCL2/MBOAT7/GSN/IL1B	61
BP	GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	29/2112	100/18670	1.154e-06	3.258e-05	2.354e-05	XCL1/PTPRC/CCR2/IL27RA/HLA-F/HLA-A/PRKCQ/CCL19/HLA-C/SASH3/HLA-G/MALT1/CD40/RIPK2/TFRC/HLA-E/ADA/HLA-B/CD226/TBX21/FAM49B/CD80/BTK/IL6/IL18/CD81/IL1R1/IL1B/NLRP3	29
BP	GO:0071347	cellular response to interleukin-1	43/2112	179/18670	1.17e-06	3.287e-05	2.375e-05	CCL5/PSMB9/XCL1/SFRP1/GBP1/PSMB8/GBP2/PSMB10/CCL19/SOX9/MYD88/VRK2/CCL13/SKP1/ICAM1/NOD2/TNIP2/MAP3K8/PSME1/RIPK2/CXCL8/CCL21/AKAP12/PCK1/NFKBIA/MAPK13/CCL18/RPS6KA4/NFKB1/HYAL1/KMO/CCL7/IKBKG/IL6/TFPI/IL1RN/NOD1/CCL17/USP10/CCL2/CCL23/IL1R1/IL1B	43
BP	GO:0072593	reactive oxygen species metabolic process	60/2112	284/18670	1.179e-06	3.299e-05	2.383e-05	PID1/CLU/GCH1/NQO1/RAC2/AKR1C3/TLR2/HBB/ITGB2/ICAM1/CRYAB/JAK2/CD36/HDAC4/SLC18A2/NDUFS4/EGFR/FBLN5/DDAH2/SH3PXD2A/CLEC7A/CYB5R4/CX3CR1/NCF4/NOX4/NDUFA13/SOD1/GPX3/PMAIP1/FOXO1/SMAD3/RAB27A/VAV1/HBD/LEP/AGTR1/IFNG/RGN/TFAP2A/HSP90AB1/PRDX6/SYK/PDK4/PINK1/MAOB/HP/GLA/FOXO3/FPR2/CYBA/SESN1/PKD2/CFLAR/CAT/NCF1/TP53/TLR6/IL1B/PTX3/EPHX2	60
BP	GO:0033048	negative regulation of mitotic sister chromatid segregation	17/2112	42/18670	1.201e-06	3.319e-05	2.398e-05	PTTG1/PTTG3P/BUB1/NDC80/MAD2L1/PLK1/TPR/ZNF207/BUB1B/ATRX/CCNB1/FBXO5/CENPF/TTK/AURKB/CDC20/TRIP13	17
BP	GO:0045576	mast cell activation	21/2112	60/18670	1.202e-06	3.319e-05	2.398e-05	RASGRP1/RAC2/LAT/LCP2/IL4R/LGALS9/GATA2/FGR/CD226/S100A13/RHOH/IL13RA2/PIK3CD/STXBP2/SYK/STXBP1/BTK/FER/PLSCR1/GAB2/LYN	21
BP	GO:0046641	positive regulation of alpha-beta T cell proliferation	11/2112	19/18670	1.202e-06	3.319e-05	2.398e-05	XCL1/CD3E/PTPRC/CCR2/LGALS9/RIPK2/HLA-E/ZAP70/SYK/IL18/CD81	11
BP	GO:0072676	lymphocyte migration	31/2112	111/18670	1.23e-06	3.38e-05	2.442e-05	CCL5/CXCL13/XCL1/CCR2/STK10/IL27RA/ITGB7/GPR183/CCL19/ITGA4/CCL13/CCR7/CD200/ICAM1/ADAM8/WASL/TNFRSF14/CXCL10/ZAP70/CCL21/TBX21/PIK3CD/CCL18/CXCL11/CCL7/SLC12A2/ADAM10/CCL17/S1PR1/CCL2/CCL23	31
BP	GO:0034101	erythrocyte homeostasis	33/2112	122/18670	1.246e-06	3.409e-05	2.463e-05	AMPD3/BMP4/RBFOX2/STAT1/INHBA/NFE2L1/AXL/PTPN2/HCLS1/JAK2/GATA2/TGFBR3/NCKAP1L/MFHAS1/P4HTM/ZFP36L1/ARNT/ADAR/TRIM58/SPI1/INPP5D/FOXO3/RB1/LYN/SH2B3/HIPK2/IKZF1/PRMT1/ISG15/PTBP3/RPS14/HOXA5/THRA	33
BP	GO:0051235	maintenance of location	67/2112	330/18670	1.291e-06	3.516e-05	2.541e-05	ENPP1/CXCL9/CCR5/XCL1/LCK/FTO/PTPRC/S100A9/CORO1A/ASPM/PLCE1/CCL19/SRI/ANK2/CCR7/ABCG1/SKP1/PTPN2/NFKBIE/DYSF/CD36/SLC18A2/HTR2B/CXCL10/TMSB10/SRGN/DAG1/PTPN6/FGF2/DZIP1/PLCG2/CCL21/BARD1/GPAA1/PLN/NFKBIA/ACACB/NFKB1/TRPC1/HTR2A/CD19/KDELR3/LEP/NBL1/ATP1A2/CXCL11/SLC8A1/P2RY6/APLNR/SLC25A23/MEST/KDELR2/PINK1/IL6/DDIT3/NR1H3/RYR3/CYBA/LYN/PKD2/GSTO1/GSTM2/ITGAV/NRIP1/GSN/IL1B/PML	67
BP	GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	14/2112	30/18670	1.344e-06	3.628e-05	2.621e-05	CCL19/SASH3/IL4R/LGALS9/MALT1/SOCS1/RIPK2/NCKAP1L/CD86/CD83/IFNG/CD80/IL18/NLRP3	14
BP	GO:0046640	regulation of alpha-beta T cell proliferation	14/2112	30/18670	1.344e-06	3.628e-05	2.621e-05	XCL1/CD3E/PTPRC/CCR2/IRF1/LGALS9/TNFRSF14/TWSG1/RIPK2/HLA-E/ZAP70/SYK/IL18/CD81	14
BP	GO:0051282	regulation of sequestering of calcium ion	34/2112	128/18670	1.361e-06	3.659e-05	2.643e-05	CXCL9/CCR5/XCL1/LCK/PTPRC/CORO1A/PLCE1/CCL19/SRI/ANK2/CCR7/HTR2B/CXCL10/PTPN6/FGF2/PLCG2/CCL21/PLN/TRPC1/HTR2A/CD19/ATP1A2/CXCL11/SLC8A1/P2RY6/APLNR/SLC25A23/DDIT3/RYR3/CYBA/LYN/PKD2/GSTO1/GSTM2	34
BP	GO:0002830	positive regulation of type 2 immune response	10/2112	16/18670	1.412e-06	3.781e-05	2.732e-05	XCL1/IDO1/CD74/IL4R/NOD2/CD86/IL6/IL18/CD81/NLRP3	10
BP	GO:0032649	regulation of interferon-gamma production	29/2112	101/18670	1.445e-06	3.841e-05	2.775e-05	XCL1/CD3E/CD2/CCR2/IL27RA/RASGRP1/TLR8/IRF8/INHBA/CCR7/SASH3/AXL/LGALS9/CD96/RIPK2/CLEC7A/HLA-DPB1/CD160/TXK/CD226/PDCD1LG2/FAM49B/PTPN22/HLA-DPA1/IL18/IL1R1/ISG15/IL1B/LILRB1	29
BP	GO:0030260	entry into host cell	35/2112	134/18670	1.466e-06	3.841e-05	2.775e-05	CCR5/SLAMF1/ITGB7/CXCR4/FCN1/CD74/AXL/ICAM1/LGALS9/TNFRSF14/TFRC/EGFR/DAG1/NPC1/CXCL8/CR1/CDK1/CD86/HTR2A/CTSB/TRIM21/HYAL1/KRT6A/CD80/TNFRSF4/SCARB2/ANPEP/SELPLG/TRIM38/TRIM26/CD81/ITGAV/GSN/CR2/PTX3	35
BP	GO:0044409	entry into host	35/2112	134/18670	1.466e-06	3.841e-05	2.775e-05	CCR5/SLAMF1/ITGB7/CXCR4/FCN1/CD74/AXL/ICAM1/LGALS9/TNFRSF14/TFRC/EGFR/DAG1/NPC1/CXCL8/CR1/CDK1/CD86/HTR2A/CTSB/TRIM21/HYAL1/KRT6A/CD80/TNFRSF4/SCARB2/ANPEP/SELPLG/TRIM38/TRIM26/CD81/ITGAV/GSN/CR2/PTX3	35
BP	GO:0051806	entry into cell of other organism involved in symbiotic interaction	35/2112	134/18670	1.466e-06	3.841e-05	2.775e-05	CCR5/SLAMF1/ITGB7/CXCR4/FCN1/CD74/AXL/ICAM1/LGALS9/TNFRSF14/TFRC/EGFR/DAG1/NPC1/CXCL8/CR1/CDK1/CD86/HTR2A/CTSB/TRIM21/HYAL1/KRT6A/CD80/TNFRSF4/SCARB2/ANPEP/SELPLG/TRIM38/TRIM26/CD81/ITGAV/GSN/CR2/PTX3	35
BP	GO:0051828	entry into other organism involved in symbiotic interaction	35/2112	134/18670	1.466e-06	3.841e-05	2.775e-05	CCR5/SLAMF1/ITGB7/CXCR4/FCN1/CD74/AXL/ICAM1/LGALS9/TNFRSF14/TFRC/EGFR/DAG1/NPC1/CXCL8/CR1/CDK1/CD86/HTR2A/CTSB/TRIM21/HYAL1/KRT6A/CD80/TNFRSF4/SCARB2/ANPEP/SELPLG/TRIM38/TRIM26/CD81/ITGAV/GSN/CR2/PTX3	35
BP	GO:0050868	negative regulation of T cell activation	31/2112	112/18670	1.518e-06	3.961e-05	2.862e-05	PLA2G2D/XCL1/CTLA4/BMP4/IRF1/RUNX3/IDO1/DLG5/LILRB2/GLI3/CD74/PTPN2/IL4R/HLA-G/LGALS9/TNFRSF14/SOCS1/TWSG1/BTN2A2/PTPN6/ERBB2/TBX21/PDCD1LG2/CD86/SOCS6/CD80/HFE/PTPN22/LRRC32/IL2RA/LILRB1	31
BP	GO:0002285	lymphocyte activation involved in immune response	43/2112	181/18670	1.604e-06	4.167e-05	3.011e-05	LCP1/RELB/PTPRC/IL27RA/CORO1A/SEMA4A/HLA-F/GPR183/CCL19/BATF/DOCK10/IRF4/IL4R/ICAM1/LGALS9/MALT1/CD40/RIPK2/TFRC/ADA/ITGAL/PLCG2/CLEC4E/TBX21/CD40LG/CD86/CD19/LEF1/HLA-DMB/RAB27A/IFNG/PTGER4/CD80/IL6/CD180/IL18/CD81/ERCC1/THOC1/TP53/IFNA1/LILRB1/NLRP3	43
BP	GO:0006790	sulfur compound metabolic process	73/2112	372/18670	1.673e-06	4.329e-05	3.128e-05	PRELP/ENPP1/NDNF/BHMT2/FMOD/CDO1/SPOCK2/PCYOX1/OGN/GSTM5/KYNU/CHST15/NFE2L1/ANGPT1/GSTM3/GSTA4/CBS/SLC26A2/PMVK/ESD/CHST3/CNDP2/PC/DCN/BGN/MCCC1/MPC2/CSPG4/GHR/AHCYL1/SP1/GAL3ST4/ACAT1/CHST11/LUM/HPGDS/NOX4/SOD1/ACACB/VCAN/HYAL1/GPX4/PCCA/HSD17B12/SUCLA2/MAT1A/GLO1/UGDH/IDUA/MICAL1/NFU1/PDK4/AHCYL2/NUBPL/TPST1/B3GNT2/ELOVL4/MPC1/HAGH/ELOVL2/GSTO1/AASS/GSTM2/ACSM5/ACSM3/ACSL5/SLC5A6/TKTL1/BPNT1/ALDH5A1/ELOVL5/B4GALT2/TXN2	73
BP	GO:0045839	negative regulation of mitotic nuclear division	19/2112	52/18670	1.825e-06	4.701e-05	3.396e-05	BMP4/PTTG1/PTTG3P/BUB1/NDC80/MAD2L1/PLK1/TPR/ZNF207/BUB1B/TOM1L1/ATRX/CCNB1/FBXO5/CENPF/TTK/AURKB/CDC20/TRIP13	19
BP	GO:0051209	release of sequestered calcium ion into cytosol	33/2112	124/18670	1.849e-06	4.743e-05	3.427e-05	CXCL9/CCR5/XCL1/LCK/PTPRC/CORO1A/PLCE1/CCL19/SRI/ANK2/CCR7/HTR2B/CXCL10/PTPN6/FGF2/PLCG2/CCL21/PLN/TRPC1/HTR2A/CD19/ATP1A2/CXCL11/SLC8A1/P2RY6/APLNR/DDIT3/RYR3/CYBA/LYN/PKD2/GSTO1/GSTM2	33
BP	GO:0019884	antigen processing and presentation of exogenous antigen	43/2112	182/18670	1.874e-06	4.787e-05	3.459e-05	PSMB9/TAP1/TAPBP/PSMB8/HLA-F/HLA-A/PSMB10/CTSF/TAP2/HLA-C/CD74/HLA-G/DYNC1LI2/CD36/CTSL/PSME1/HLA-E/KIF11/KIF15/HLA-DRA/KIF3B/HLA-DPB1/HLA-B/SEC31A/FCGR1B/NCF4/KIF2C/KIF4A/DYNC1I1/HLA-DMA/HLA-DMB/RACGAP1/CLEC4A/HLA-DQB2/DCTN6/IKBKG/HLA-DPA1/CAPZA1/OSBPL1A/CYBA/NCF1/ITGAV/KIF23	43
BP	GO:0000280	nuclear division	78/2112	407/18670	1.94e-06	4.936e-05	3.566e-05	BMP4/CDKN1C/IGF1/TACC3/BTC/ASPM/PTTG1/PTTG3P/MKI67/BUB1/NFE2L1/NUSAP1/SIRT7/UBE2C/NCAPD2/NDC80/MAD2L1/GOLGA2/PLK1/TPX2/BORA/CDC14B/UBE2B/KIF11/CDCA8/NCAPH/KIF18B/SPHK1/CDC25B/RPL24/KIF3B/NCAPG/TPR/MAP9/DLGAP5/ZNF207/STAG2/BUB1B/KIF2C/LRP5/KIF4A/ARHGEF10/DAZL/TOP2A/PRC1/NEK2/TOM1L1/MYBL1/RMI1/ATRX/CKS2/RACGAP1/ZWINT/STAG3/CCNB1/TERF1/FBXO5/NIPBL/CEP85/CENPF/REC8/TTK/CHMP2B/AURKB/RB1/CDC20/TUBG2/KIF20B/SMC4/ACTR3/TRIP13/CCNE2/AURKA/KIFC1/IL1B/ACTR2/CHMP1B/KIF23	78
BP	GO:2000816	negative regulation of mitotic sister chromatid separation	16/2112	39/18670	1.995e-06	5.056e-05	3.653e-05	PTTG1/PTTG3P/BUB1/NDC80/MAD2L1/PLK1/TPR/ZNF207/BUB1B/CCNB1/FBXO5/CENPF/TTK/AURKB/CDC20/TRIP13	16
BP	GO:0000819	sister chromatid segregation	44/2112	189/18670	2.179e-06	5.499e-05	3.973e-05	TACC3/PTTG1/PTTG3P/BUB1/NUSAP1/NCAPD2/NDC80/MAD2L1/PLK1/CDCA8/NCAPH/KIF18B/NCAPG/TPR/DLGAP5/ZNF207/STAG2/BUB1B/KIF2C/KIF4A/TOP2A/PRC1/NEK2/FEN1/ATRX/RACGAP1/ZWINT/STAG3/CCNB1/FBXO5/NIPBL/CENPF/REC8/TTK/CHMP2B/AURKB/RB1/CDC20/TUBG2/SMC4/TRIP13/KIFC1/CHMP1B/KIF23	44
BP	GO:0002724	regulation of T cell cytokine production	14/2112	31/18670	2.195e-06	5.517e-05	3.986e-05	XCL1/CCR2/HLA-F/TNFRSF1B/SASH3/MALT1/TBX21/HFE/IL6/IL18/CD81/IL1R1/IL1B/NLRP3	14
BP	GO:0010639	negative regulation of organelle organization	76/2112	395/18670	2.244e-06	5.616e-05	4.058e-05	BMP4/IGF1/CORO1A/CLU/LILRB2/ADD3/ARPIN/TMOD1/PTTG1/SKI/PTTG3P/BUB1/PFN2/MAP4/NDC80/MAD2L1/PLK1/TMEM14A/TMSB10/CKAP2/UBE2B/DLC1/TAF7/FGF13/TPR/WAS/HGF/ZNF207/BUB1B/TUBB4A/GMFG/TOP2A/NEK2/TOM1L1/DNMT1/CORO2B/ATRX/FEZ1/MYOC/KANK1/HIGD1A/PAX5/MCM2/LMOD1/CCNB1/MTF2/TERF1/FBXO5/PARP1/SPI1/CAMSAP2/PINK1/CENPF/TTK/MAP1B/JARID2/CAPZA1/VILL/LMNA/AURKB/CDC20/SLC25A5/CLIP3/HMGA1/WASF2/ERCC1/S1PR1/FEZ2/SETMAR/CCNF/TRIP13/PFN1/TP53/SPTBN1/GSN/CDH5	76
BP	GO:0030218	erythrocyte differentiation	31/2112	114/18670	2.291e-06	5.712e-05	4.127e-05	BMP4/RBFOX2/STAT1/INHBA/NFE2L1/PTPN2/HCLS1/JAK2/GATA2/TGFBR3/NCKAP1L/MFHAS1/P4HTM/ZFP36L1/ARNT/ADAR/TRIM58/SPI1/INPP5D/FOXO3/RB1/LYN/SH2B3/HIPK2/IKZF1/PRMT1/ISG15/PTBP3/RPS14/HOXA5/THRA	31
BP	GO:0051208	sequestering of calcium ion	34/2112	131/18670	2.404e-06	5.969e-05	4.312e-05	CXCL9/CCR5/XCL1/LCK/PTPRC/CORO1A/PLCE1/CCL19/SRI/ANK2/CCR7/HTR2B/CXCL10/PTPN6/FGF2/PLCG2/CCL21/PLN/TRPC1/HTR2A/CD19/ATP1A2/CXCL11/SLC8A1/P2RY6/APLNR/SLC25A23/DDIT3/RYR3/CYBA/LYN/PKD2/GSTO1/GSTM2	34
BP	GO:0097305	response to alcohol	51/2112	233/18670	2.492e-06	6.164e-05	4.454e-05	CCR5/SFRP1/LRP6/CDO1/PENK/NQO1/CCL19/INHBA/AKR1C3/OXCT1/CCR7/NFE2L1/USP46/ICAM1/PMVK/DAG1/TGFBR3/BLM/MAP4K1/CCL21/CDK1/BAK1/CD27/LANCL2/SOD1/EFNA5/RBP4/LEP/CSN1S1/RPS4X/PTGFR/PTGER4/CCL7/ADIPOQ/P2RY6/CCND1/FOSL1/PARP1/SPI1/MAOB/TYMS/FOXO3/CYBA/SDF4/CAT/TUFM/ALAD/RPL10A/GSN/P2RY4/ACTR2	51
BP	GO:0033046	negative regulation of sister chromatid segregation	17/2112	44/18670	2.592e-06	6.384e-05	4.613e-05	PTTG1/PTTG3P/BUB1/NDC80/MAD2L1/PLK1/TPR/ZNF207/BUB1B/ATRX/CCNB1/FBXO5/CENPF/TTK/AURKB/CDC20/TRIP13	17
BP	GO:0051283	negative regulation of sequestering of calcium ion	33/2112	126/18670	2.712e-06	6.655e-05	4.808e-05	CXCL9/CCR5/XCL1/LCK/PTPRC/CORO1A/PLCE1/CCL19/SRI/ANK2/CCR7/HTR2B/CXCL10/PTPN6/FGF2/PLCG2/CCL21/PLN/TRPC1/HTR2A/CD19/ATP1A2/CXCL11/SLC8A1/P2RY6/APLNR/DDIT3/RYR3/CYBA/LYN/PKD2/GSTO1/GSTM2	33
BP	GO:1905819	negative regulation of chromosome separation	16/2112	40/18670	2.977e-06	7.276e-05	5.257e-05	PTTG1/PTTG3P/BUB1/NDC80/MAD2L1/PLK1/TPR/ZNF207/BUB1B/CCNB1/FBXO5/CENPF/TTK/AURKB/CDC20/TRIP13	16
BP	GO:0045930	negative regulation of mitotic cell cycle	67/2112	338/18670	3.082e-06	7.502e-05	5.42e-05	PSMB9/CDKN2C/GAS1/BMP4/PSMB8/TFDP2/PSMB10/PTTG1/FOXC1/PTTG3P/BUB1/SKP1/NDC80/KANK2/MAD2L1/PLK1/TIMP2/PSME1/EGFR/CDC14B/BTN2A2/CHFR/BLM/E2F8/RPL24/FHL1/TPR/CDK1/MAGI2/ZNF207/EZH2/BUB1B/MCPH1/TOP2A/TOM1L1/SMAD3/ATRX/PLK2/DONSON/ZWINT/ZFP36L1/CCNB1/DACT1/CCND1/FBXO5/CENPF/TTK/MIIP/AURKB/RB1/CDC20/FBXL7/SYF2/PKD2/NLE1/NAE1/ZFP36L2/PRMT1/SETMAR/PCBP4/TRIP13/TP53/CCL2/AURKA/TOPBP1/PML/BRINP1	67
BP	GO:0070167	regulation of biomineral tissue development	27/2112	94/18670	3.267e-06	7.913e-05	5.717e-05	ENPP1/NELL1/BMP4/ANKH/DDR2/MGP/SOX9/LTBP3/BMPR1A/COMP/SRGN/CCR1/PTN/SMAD3/KL/NOTCH1/HEY2/SLC8A1/TFAP2A/ACVR1/FBXO5/TGFB3/BMP2K/HEY1/S1PR1/ATRAID/ISG15	27
BP	GO:0050777	negative regulation of immune response	37/2112	150/18670	3.276e-06	7.913e-05	5.717e-05	SLAMF8/XCL1/PTPRC/CTLA4/TNFAIP3/CCR2/IL27RA/HLA-F/IL7R/ANGPT1/PTPN2/IL4R/HLA-G/LGALS9/SAMSN1/NMI/CD96/TNFRSF14/TRAFD1/HLA-E/PTPN6/CR1/CD160/TBX21/IL13RA2/ADAR/HFE/TGFB3/FER/INPP5D/NR1H3/LYN/SPINK5/THOC1/IL2RA/MMP12/LILRB1	37
BP	GO:1902622	regulation of neutrophil migration	15/2112	36/18670	3.303e-06	7.947e-05	5.742e-05	SLAMF8/XCL1/RAC2/CCL19/CCR7/JAM3/CD74/ADAM8/DYSF/THBS4/CXCL8/CCL21/CAMK1D/NCKAP1L/IL1R1	15
BP	GO:0002708	positive regulation of lymphocyte mediated immunity	29/2112	105/18670	3.425e-06	8.208e-05	5.931e-05	XCL1/PTPRC/RASGRP1/HLA-F/HLA-A/HLA-C/SASH3/HLA-G/MALT1/CD40/MICB/TFRC/CRTAM/HLA-E/SH2D1A/CD160/HLA-B/CD226/TBX21/CADM1/VAV1/FAM49B/BTK/IL6/IL18/CD81/IL1R1/IL1B/NLRP3	29
BP	GO:0032663	regulation of interleukin-2 production	19/2112	54/18670	3.511e-06	8.382e-05	6.056e-05	XCL1/CD3E/PTPRC/TNFAIP3/CCR2/GBP1/PRKCQ/SASH3/IRF4/MALT1/PRKD2/RIPK2/CLEC7A/TBX21/CD86/CD83/CD80/SPTBN1/IL1B	19
BP	GO:0060348	bone development	48/2112	217/18670	3.578e-06	8.51e-05	6.149e-05	PTPRC/BMP4/LRP6/IGF1/SCARA3/BBX/FGF18/FLI1/SOX9/SEMA4D/GLI3/LTBP3/FOXC1/SKI/MEIS1/NPR2/SULF1/COCH/COMP/SHOX2/DHRS3/PTPN6/COL14A1/GLG1/VKORC1/LRP5/MCPH1/DCHS1/PLS3/PTPN11/MYOC/LEP/RGN/TFAP2A/ALPL/PTGER4/TGFB3/TULP3/AKAP13/MEGF8/FAT4/PIP4K2A/MBTPS2/SH2B3/WASF2/HOXA11/TP53/LILRB1	48
BP	GO:0051985	negative regulation of chromosome segregation	17/2112	45/18670	3.728e-06	8.831e-05	6.381e-05	PTTG1/PTTG3P/BUB1/NDC80/MAD2L1/PLK1/TPR/ZNF207/BUB1B/ATRX/CCNB1/FBXO5/CENPF/TTK/AURKB/CDC20/TRIP13	17
BP	GO:0042130	negative regulation of T cell proliferation	20/2112	59/18670	3.793e-06	8.95e-05	6.467e-05	PLA2G2D/XCL1/CTLA4/BMP4/IDO1/DLG5/LILRB2/HLA-G/LGALS9/TNFRSF14/TWSG1/BTN2A2/PTPN6/ERBB2/PDCD1LG2/CD86/CD80/LRRC32/IL2RA/LILRB1	20
BP	GO:0071902	positive regulation of protein serine/threonine kinase activity	66/2112	334/18670	4.065e-06	9.556e-05	6.905e-05	KITLG/PTPRC/BMP4/IGF1/RASGRP1/CSK/PLCE1/FGF18/CXCR4/CCL19/TPD52L1/CCND2/PPP2CA/DUSP5/LPAR1/CD74/MAP3K11/NOD2/ADAM8/JAK2/PDGFD/CD40/HTR2B/MAP3K8/RIPK2/EGFR/FGF2/MAP4K1/CSPG4/CCNT1/GHR/ERBB2/CDK1/HGF/EZH2/CD40LG/NOX4/SOD1/FZD4/HTR2A/PTPN11/CKS2/MAP3K2/FPR1/HIGD1A/IFNG/CCNB1/FLT3/HSP90AB1/PAK1/ADIPOQ/SYK/CCND1/DBF4/IKBKG/CKS1B/TGFB3/MAPKAPK2/AKAP13/DUSP6/NOD1/SHC2/PKD2/CD81/TLR6/IL1B	66
BP	GO:0010001	glial cell differentiation	48/2112	218/18670	4.093e-06	9.587e-05	6.927e-05	WASF3/CDKN2C/CSK/CLU/TNFRSF1B/CXCR4/PLP1/SOX9/GLI3/NTRK2/SKI/PARD3/LPAR1/ZNF365/NFE2L1/TLR2/LAMA2/MXRA8/EGFR/DAG1/NFIB/ASPA/ERBB2/CDK1/FA2H/SOX2/PTN/CDH2/SOD1/ARHGEF10/ADAM22/LEF1/PTPN11/DAAM2/CD9/NOTCH1/MYOC/IL6ST/IFNG/IL6/FPR2/LYN/MPP5/TENM4/WDR1/SH3TC2/GSN/IL1B	48
BP	GO:0002286	T cell activation involved in immune response	29/2112	106/18670	4.211e-06	9.825e-05	7.099e-05	LCP1/RELB/SEMA4A/GPR183/CCL19/BATF/IRF4/IL4R/ICAM1/LGALS9/MALT1/RIPK2/ITGAL/CLEC4E/TBX21/CD86/LEF1/HLA-DMB/RAB27A/IFNG/PTGER4/CD80/IL6/IL18/CD81/TP53/IFNA1/LILRB1/NLRP3	29
BP	GO:0046849	bone remodeling	26/2112	90/18670	4.393e-06	0.0001021	7.377e-05	SFRP1/TNFAIP3/GDF5/LRP6/TNFRSF11B/CSK/RAC2/LTBP3/TCIRG1/ADAM8/TFRC/EGFR/PTN/LRP5/NOX4/CA2/LEP/SYK/PDK4/TGFB3/IL6/CD38/INPP5D/SNX10/S1PR1/PTH1R	26
BP	GO:0042089	cytokine biosynthetic process	32/2112	123/18670	4.453e-06	0.0001031	7.45e-05	CD3E/PTPRC/CCR2/IRF1/TLR8/PRKCQ/INHBA/IRF4/CD74/LTB/IGF2BP3/IRF7/JAK2/NMI/CLEC7A/AKAP12/CX3CR1/NFKB1/CD86/IFNG/SYK/CD80/HSPB1/MAPKAPK2/IL6/INPP5D/UBE2J1/IL18/NOD1/TLR6/IL1B/LILRB1	32
BP	GO:0048871	multicellular organismal homeostasis	88/2112	485/18670	4.573e-06	0.0001055	7.622e-05	AMPD3/FTO/TNFAIP3/CCR2/TNFRSF11B/CORO1A/CSK/RAC2/HOXC10/CXCR4/NDN/SERPINA3/SOX9/IL15/LTBP3/FOXC1/ACADVL/SASH3/IRF4/TCIRG1/IL4R/DIO2/NOVA1/NOD2/ADAM8/JAK2/CD36/LYZ/PLAC8/YAP1/GATA2/AKR1B1/TFRC/EGFR/PASK/TRPV2/BARD1/FA2H/PER2/NOX4/TP63/SOD1/ACACB/HTR2A/FOXO1/PTPN11/CA2/RBP4/NOTCH1/ARNTL/LEP/PIK3CA/ADIPOQ/SYK/BBS1/FABP5/EDNRB/PDK4/HFE/HSPB1/WWTR1/AKT3/IL6/CD38/G0S2/INPP5D/RCN3/DDIT3/NR1H3/UCP2/RB1/IL18/FABP4/ABHD6/ACADL/SNX10/HADH/NPR3/S1PR1/PTH1R/RAB11FIP2/UGCG/PRKAB1/NPHP4/YBX2/IL1B/THRA/CTSH	88
BP	GO:0030041	actin filament polymerization	42/2112	182/18670	4.655e-06	0.000107	7.73e-05	WASF3/CORO1A/ADD3/ARPIN/TMOD1/CCR7/COTL1/HCLS1/PFN2/MSRB2/ICAM1/JAK2/COBL/WASL/PSTPIP2/TMSB10/CCL21/WAS/CDC42EP3/GAS7/NCKAP1L/GMFG/VASP/ARPC5L/KANK1/LMOD1/MYO1C/CTTN/FER/CAPZA1/VILL/AP1AR/ANG/HCK/ARPC1A/ABI2/ACTR3/PFN1/IQGAP2/SPTBN1/GSN/ACTR2	42
BP	GO:0042267	natural killer cell mediated cytotoxicity	20/2112	60/18670	5.088e-06	0.0001165	8.418e-05	CORO1A/RASGRP1/HLA-F/GZMB/HLA-G/LGALS9/MICB/CRTAM/HLA-E/PTPN6/SH2D1A/CD160/CD226/CADM1/RAB27A/VAV1/LEP/IL18/SLAMF7/LILRB1	20
BP	GO:0032729	positive regulation of interferon-gamma production	21/2112	65/18670	5.224e-06	0.000118	8.522e-05	CD3E/CD2/CCR2/IL27RA/RASGRP1/TLR8/IRF8/SASH3/LGALS9/RIPK2/CLEC7A/HLA-DPB1/CD160/TXK/CD226/FAM49B/PTPN22/HLA-DPA1/IL18/IL1R1/IL1B	21
BP	GO:0072678	T cell migration	21/2112	65/18670	5.224e-06	0.000118	8.522e-05	CCL5/CXCL13/XCL1/CCR2/IL27RA/ITGB7/GPR183/ITGA4/CD200/ICAM1/ADAM8/TNFRSF14/CXCL10/ZAP70/CCL21/PIK3CD/CXCL11/SLC12A2/ADAM10/S1PR1/CCL2	21
BP	GO:0033077	T cell differentiation in thymus	22/2112	70/18670	5.227e-06	0.000118	8.522e-05	CD3D/CD3E/PTPRC/BMP4/BCL11B/RASGRP1/IL7R/GLI3/CCR7/CD74/PTPN2/CD3G/ADAM8/ADA/ZAP70/ERBB2/SOD1/FZD7/DOCK2/ZFP36L1/ZFP36L2/TP53	22
BP	GO:0050766	positive regulation of phagocytosis	22/2112	70/18670	5.227e-06	0.000118	8.522e-05	IL2RG/PTPRC/IL15RA/IL2RB/IL15/SIRPG/CD36/GATA2/CLEC7A/CAMK1D/NCKAP1L/SOD1/RAB27A/DOCK2/IFNG/FPR2/CYBA/MERTK/ITGAV/CCL2/IL1B/PTX3	22
BP	GO:0042107	cytokine metabolic process	32/2112	124/18670	5.358e-06	0.0001205	8.705e-05	CD3E/PTPRC/CCR2/IRF1/TLR8/PRKCQ/INHBA/IRF4/CD74/LTB/IGF2BP3/IRF7/JAK2/NMI/CLEC7A/AKAP12/CX3CR1/NFKB1/CD86/IFNG/SYK/CD80/HSPB1/MAPKAPK2/IL6/INPP5D/UBE2J1/IL18/NOD1/TLR6/IL1B/LILRB1	32
BP	GO:0032633	interleukin-4 production	14/2112	33/18670	5.442e-06	0.0001219	8.808e-05	ITK/CD3E/PRKCQ/SASH3/IRF4/LGALS9/HLA-E/CD40LG/CD86/CD83/LEF1/NOTCH1/SYK/NLRP3	14
BP	GO:0060401	cytosolic calcium ion transport	40/2112	171/18670	5.475e-06	0.0001222	8.83e-05	CXCL9/CCR5/XCL1/LCK/PTPRC/CORO1A/PLCE1/CCL19/SRI/CACNA2D1/ANK2/CCR7/HTR2B/CXCL10/PTPN6/FGF2/PLCG2/CCL21/BAK1/PLN/AFG3L2/MICU1/MS4A1/TRPC1/HTR2A/CD19/ATP1A2/CXCL11/SLC8A1/P2RY6/APLNR/SLC25A23/DDIT3/RYR3/CYBA/LYN/PKD2/GSTO1/GSTM2/PML	40
BP	GO:1902624	positive regulation of neutrophil migration	13/2112	29/18670	5.629e-06	0.0001252	9.045e-05	XCL1/RAC2/CCL19/CCR7/CD74/ADAM8/DYSF/THBS4/CXCL8/CCL21/CAMK1D/NCKAP1L/IL1R1	13
BP	GO:0071356	cellular response to tumor necrosis factor	59/2112	291/18670	5.68e-06	0.0001259	9.095e-05	CCL5/TRAF3/PID1/AIM2/PSMB9/XCL1/SFRP1/TNFAIP3/GBP1/PSMB8/TNFRSF11B/BIRC3/TNFRSF1B/GBP2/STAT1/TRAF1/PSMB10/CCL19/CCL13/PTPN2/LTB/ICAM1/JAK2/HDAC4/CD40/CDIP1/TNFRSF14/PSME1/SPHK1/CXCL8/CCL21/AKAP12/CD27/PCK1/NFKBIA/CD40LG/CCL18/NFKB1/CASP1/HYAL1/ZFP36L1/CCL7/ADIPOQ/SYK/IKBKG/TNFRSF4/SGMS1/FOXO3/CYBA/FABP4/CLIP3/CEBPA/CCL17/ZFP36L2/TNFRSF9/CASP4/CCL2/CCL23/TNFRSF17	59
BP	GO:0010810	regulation of cell-substrate adhesion	47/2112	215/18670	6.3e-06	0.0001391	0.0001005	PIK3R1/NDNF/CD3E/SFRP1/EPHA3/GBP1/LIMCH1/DDR2/RAC2/SPOCK2/SPOCK1/CCR7/EMP2/ITGB1BP1/ECM2/JAK2/CD36/PDPN/DAG1/DLC1/COL8A1/CCL21/EDIL3/PTN/DOCK1/SKAP1/FZD4/EFNA5/SMAD3/HSD17B12/FZD7/CORO2B/NOTCH1/MYOC/KANK1/PPM1F/PLEKHA2/RHOD/AP1AR/FBLN1/FERMT1/SEMA3E/KDR/CASK/LIMS2/COL16A1/MMP12	47
BP	GO:0090307	mitotic spindle assembly	19/2112	56/18670	6.497e-06	0.000143	0.0001033	GOLGA2/PLK1/TPX2/KIF11/KIF3B/TPR/MAP9/ZNF207/STAG2/KIF4A/ARHGEF10/NEK2/RACGAP1/CHMP2B/AURKB/CDC20/KIFC1/CHMP1B/KIF23	19
BP	GO:0034612	response to tumor necrosis factor	62/2112	312/18670	6.532e-06	0.0001432	0.0001035	CCL5/TRAF3/PID1/AIM2/PSMB9/XCL1/SFRP1/TNFAIP3/GBP1/PSMB8/TNFRSF11B/BIRC3/GCH1/TNFRSF1B/GBP2/STAT1/TRAF1/PSMB10/CCL19/CCL13/PTPN2/LTB/ICAM1/JAK2/HDAC4/CD40/CDIP1/TNFRSF14/PSME1/SPHK1/CXCL8/SELE/CCL21/AKAP12/CD27/PCK1/NFKBIA/CD40LG/CCL18/NFKB1/CASP1/HYAL1/ZFP36L1/CCL7/ADIPOQ/SYK/IKBKG/TNFRSF4/SGMS1/FOXO3/CYBA/ADAM10/FABP4/CLIP3/CEBPA/CCL17/ZFP36L2/TNFRSF9/CASP4/CCL2/CCL23/TNFRSF17	62
BP	GO:0030500	regulation of bone mineralization	23/2112	76/18670	6.565e-06	0.0001434	0.0001036	ENPP1/NELL1/BMP4/ANKH/DDR2/MGP/SOX9/LTBP3/BMPR1A/COMP/SRGN/CCR1/PTN/SMAD3/KL/SLC8A1/TFAP2A/ACVR1/TGFB3/BMP2K/S1PR1/ATRAID/ISG15	23
BP	GO:0045123	cellular extravasation	20/2112	61/18670	6.77e-06	0.0001474	0.0001065	CCR2/IL27RA/ITGB7/ITGA4/ITGB2/ICAM1/SELL/ADAM8/PDGFD/SELE/CCL21/CX3CR1/PIK3CD/LEP/PECAM1/PTGER4/FER/SELPLG/CCL2/IL1R1	20
BP	GO:0030282	bone mineralization	30/2112	114/18670	6.831e-06	0.0001482	0.0001071	ENPP1/NELL1/BMP4/ANKH/IGF1/DDR2/MGP/PTHLH/SOX9/LTBP3/BMPR1A/COMP/FGR/SRGN/CCR1/PTN/SMAD3/KL/LEP/SLC8A1/TFAP2A/ACVR1/TGFB3/BMP2K/SNX10/S1PR1/PTH1R/SBNO2/ATRAID/ISG15	30
BP	GO:0010952	positive regulation of peptidase activity	44/2112	197/18670	6.89e-06	0.000149	0.0001076	AIM2/LCK/S100A9/PCOLCE2/ANTXR1/BID/TNFSF10/LGALS9/MALT1/JAK2/PSME1/RIPK2/DLC1/DAP/CASP10/CLEC7A/CR1/BAK1/ASPH/NDUFA13/ARL6IP5/PCOLCE/CASP1/PMAIP1/ADRM1/CYFIP2/SMAD3/FAM162A/VCP/CASP5/PPM1F/SYK/PINK1/APAF1/RCN3/FBLN1/LYN/NOD1/CFLAR/CASP4/GSN/PML/CTSH/NLRP3	44
BP	GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism	48/2112	222/18670	6.92e-06	0.0001491	0.0001077	CCL5/LAMP3/STAT1/CXCR4/FCN1/SLPI/NUCKS1/CD74/APOBEC3G/CHD1/OAS1/LGALS9/ISG20/PC/SRPK1/IFI27/OASL/CXCL8/CCNT1/SP1/FAM111A/TOP2A/LEF1/TRIM21/NOTCH1/FBXL2/GTF2F1/ADAR/MPHOSPH8/KRT6A/OAS3/POLR2L/TRIM38/IFIT5/CHMP2B/PLSCR1/CFL1/KPNA2/CXCL6/RSF1/TRIM26/MX1/ZC3HAV1/ITGAV/ISG15/GSN/PTX3/PML	48
BP	GO:0051983	regulation of chromosome segregation	28/2112	103/18670	7.002e-06	0.0001503	0.0001086	TACC3/PTTG1/PTTG3P/MKI67/BUB1/NDC80/MAD2L1/SMC6/PLK1/TPR/DLGAP5/ZNF207/BUB1B/KIF2C/NEK2/FEN1/ATRX/RACGAP1/ECT2/CCNB1/FBXO5/NIPBL/CENPF/TTK/AURKB/RB1/CDC20/TRIP13	28
BP	GO:0002690	positive regulation of leukocyte chemotaxis	25/2112	87/18670	7.398e-06	0.0001566	0.0001132	CCL5/CXCL13/XCL1/CCR2/RAC2/CCL19/CCR7/CD74/LGALS9/DYSF/GPSM3/CXCL10/THBS4/CXCL8/CCL21/CCR1/CAMK1D/PTN/NCKAP1L/CCL7/IL6/FPR2/ADAM10/VEGFB/PLA2G7	25
BP	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	25/2112	87/18670	7.398e-06	0.0001566	0.0001132	CCL5/PIK3R1/IGF1/SOX9/SEMA4D/NTRK2/ANGPT1/HCLS1/JAK2/PDGFD/FGR/PTPN6/DCN/HGF/PIK3CD/MYOC/LEP/PIK3CA/FLT3/IL18/LYN/KDR/CAT/NCF1/PRR5L	25
BP	GO:0043303	mast cell degranulation	17/2112	47/18670	7.422e-06	0.0001566	0.0001132	RASGRP1/RAC2/LAT/IL4R/LGALS9/GATA2/FGR/S100A13/IL13RA2/PIK3CD/STXBP2/SYK/STXBP1/BTK/FER/GAB2/LYN	17
BP	GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	17/2112	47/18670	7.422e-06	0.0001566	0.0001132	RUNX3/CCL19/SASH3/IRF4/IL4R/LGALS9/MALT1/SOCS1/RIPK2/TBX21/NCKAP1L/CD86/CD83/IFNG/CD80/IL18/NLRP3	17
BP	GO:0045058	T cell selection	17/2112	47/18670	7.422e-06	0.0001566	0.0001132	CD3D/CD3E/PTPRC/BCL11B/IL15/BATF/GLI3/CCR7/IRF4/CD74/PTPN2/CD3G/ZAP70/TBX21/DOCK2/SYK/IL6	17
BP	GO:0043062	extracellular structure organization	78/2112	422/18670	7.869e-06	0.0001655	0.0001196	LCP1/NDNF/TNFRSF11B/FMOD/DDR2/TNFRSF1B/ITGB7/SPOCK2/ADAM19/DPT/SOX9/ITGA4/FOXC1/MMP1/ABCG1/NFKB2/ANTXR1/JAM3/MFAP4/ITGB2/HTRA1/KAZALD1/SULF1/ECM2/LAMA2/ICAM1/EFEMP2/ADAM8/ADAMTSL2/CD36/TIMP2/COMP/CTSL/FBLN5/RECK/COL8A2/SH3PXD2A/PDPN/DAG1/FGF2/DCN/BGN/ITGAL/COL8A1/COL14A1/SPINT2/LUM/ICAM3/VCAN/HYAL1/SMAD3/COL15A1/HSD17B12/NOTCH1/LIPG/ITGA10/AGTR1/PECAM1/CETP/ITGAX/IL6/MYH11/FBLN1/RB1/FERMT1/ADAM10/CTRB2/KDR/CFLAR/SPINK5/LIPC/ITGAV/PLA2G7/COL16A1/ITGAE/MMP12/PTX3/SOAT2	78
BP	GO:0031334	positive regulation of protein complex assembly	55/2112	268/18670	8.022e-06	0.0001676	0.0001211	CXCL13/LCP1/AIM2/CORO1A/CLU/ARPIN/MMP1/TPPP3/CCR7/BID/PFN2/RASIP1/ICAM1/CD36/WASL/CLEC7A/CCL21/WAS/CDC42EP3/PLEK/NCKAP1L/GMFG/SKAP1/PMAIP1/VASP/ARPC5L/VCP/IFNG/LMOD1/MECP2/TERF1/PAK1/MYO1C/SYK/FOSL1/PARP1/CTTN/PINK1/MAP1B/FER/AP1AR/CUL4B/HCK/ARPC1A/ERCC1/ABI2/ACTR3/PFN1/TP53/IQGAP2/GSN/TLR6/CDH5/ACTR2/GTF2H5	55
BP	GO:0050714	positive regulation of protein secretion	55/2112	268/18670	8.022e-06	0.0001676	0.0001211	AIM2/CD2/IGF1/RASGRP1/TLR8/MYH10/FCN1/CCL19/SRI/OXCT1/ABCG1/TLR2/IL4R/LGALS9/NOD2/ADAM8/WLS/JAK2/IFIH1/HTR2B/TNFRSF14/RIPK2/FGR/CRTAM/EGFR/HLA-E/TM7SF3/MPC2/CD160/CLEC4E/AKAP12/TCF7L2/CADM1/DDX58/CASP1/RBP4/IFNG/OR51E2/PTGER4/STX4/SYK/TGFB3/TNFRSF4/IL6/PTPN22/CD38/SYBU/FERMT1/ANG/PANX1/SPTBN1/IL1B/MMP12/GPR27/NLRP3	55
BP	GO:0051302	regulation of cell division	39/2112	168/18670	8.644e-06	0.0001797	0.0001298	NAP1L2/BTC/ASPM/CETN2/FGF7/ITGB1BP1/PLK1/PDGFD/HTR2B/CDC14B/EVI2B/FGF2/BLM/KIF18B/E2F8/THBS4/CDC25B/KIF3B/MAP9/PTN/TP63/PRC1/CSPP1/KIF20A/PLK2/RACGAP1/ECT2/SSTR5/FGF9/TGFB3/KLHL9/AURKB/KLHL21/VEGFB/KIF20B/CAT/AURKA/IL1B/KIF23	39
BP	GO:0007259	JAK-STAT cascade	37/2112	156/18670	8.667e-06	0.0001797	0.0001298	CCL5/PTPRC/CRLF1/CCR2/IGF1/STAT1/IL15/PPP2CA/PTPN2/HCLS1/CRLF3/JAK2/NMI/CD40/SOCS1/AKR1B1/STAT4/GHR/SOCS2/NOTCH1/LEP/IL6ST/IFNG/PECAM1/SOCS6/PRL/FLT3/IL10RA/CTF1/IL6/FER/IL18/LYN/SH2B3/PKD2/CCL2/IFNA1	37
BP	GO:0010965	regulation of mitotic sister chromatid separation	19/2112	57/18670	8.719e-06	0.0001797	0.0001298	TACC3/PTTG1/PTTG3P/BUB1/NDC80/MAD2L1/PLK1/TPR/DLGAP5/ZNF207/BUB1B/CCNB1/FBXO5/CENPF/TTK/AURKB/RB1/CDC20/TRIP13	19
BP	GO:1903428	positive regulation of reactive oxygen species biosynthetic process	19/2112	57/18670	8.719e-06	0.0001797	0.0001298	CLU/HBB/ITGB2/ICAM1/JAK2/CD36/HDAC4/DDAH2/CLEC7A/SMAD3/RAB27A/IFNG/HSP90AB1/FOXO3/CYBA/PKD2/TLR6/IL1B/PTX3	19
BP	GO:0002828	regulation of type 2 immune response	13/2112	30/18670	8.905e-06	0.0001827	0.000132	XCL1/CCR2/IL27RA/IDO1/CD74/IL4R/NOD2/TBX21/CD86/IL6/IL18/CD81/NLRP3	13
BP	GO:0042108	positive regulation of cytokine biosynthetic process	21/2112	67/18670	8.923e-06	0.0001827	0.000132	CD3E/PTPRC/CCR2/IRF1/TLR8/PRKCQ/IRF4/CD74/LTB/JAK2/CLEC7A/AKAP12/CD86/IFNG/SYK/CD80/HSPB1/MAPKAPK2/IL6/TLR6/IL1B	21
BP	GO:0031214	biomineral tissue development	38/2112	163/18670	1.01e-05	0.0002061	0.0001489	ENPP1/NELL1/BMP4/ANKH/IGF1/DDR2/MGP/PTHLH/SOX9/LTBP3/ITGB1BP1/TCIRG1/BMPR1A/COMP/FGR/SRGN/CCR1/PTN/FOXO1/SMAD3/KL/NOTCH1/LEP/HEY2/SLC8A1/TFAP2A/ALPL/ACVR1/FBXO5/TGFB3/BMP2K/HEY1/SNX10/S1PR1/PTH1R/SBNO2/ATRAID/ISG15	38
BP	GO:0001101	response to acid chemical	66/2112	343/18670	1.017e-05	0.0002068	0.0001494	PID1/SFRP1/EPHA3/CDO1/WNT5B/NQO1/CCL19/SOX9/SIPA1/NTRK2/AKR1C3/CCR7/TLR2/GLRB/SIX1/ICAM1/CD36/PDGFD/MICB/SOCS1/YAP1/AKR1B1/EGFR/CPEB1/TGFBR3/AKR1C1/CCL21/PCK1/ID3/PTN/LANCL2/NDUFA13/FZD4/DNMT1/FOXO1/FZD7/RBP4/CD9/LEP/CCNB1/OR51E2/PTGFR/PTGER4/SMARCD1/ADIPOQ/P2RY6/PDK4/PINK1/CD38/TYMS/BCL11A/CFL1/TESC/CYBA/SESN1/LYN/IGFBP2/KDR/PKD2/CAT/ALAD/COL16A1/GSN/P2RY4/CTSH/BRINP1	66
BP	GO:0002279	mast cell activation involved in immune response	17/2112	48/18670	1.029e-05	0.0002079	0.0001502	RASGRP1/RAC2/LAT/IL4R/LGALS9/GATA2/FGR/S100A13/IL13RA2/PIK3CD/STXBP2/SYK/STXBP1/BTK/FER/GAB2/LYN	17
BP	GO:0002711	positive regulation of T cell mediated immunity	17/2112	48/18670	1.029e-05	0.0002079	0.0001502	XCL1/PTPRC/HLA-F/HLA-A/HLA-C/SASH3/HLA-G/MALT1/HLA-E/HLA-B/FAM49B/IL6/IL18/CD81/IL1R1/IL1B/NLRP3	17
BP	GO:0001910	regulation of leukocyte mediated cytotoxicity	23/2112	78/18670	1.061e-05	0.0002137	0.0001544	XCL1/PTPRC/RASGRP1/HLA-F/HLA-A/IL7R/HLA-C/HLA-G/ICAM1/LGALS9/MICB/CRTAM/HLA-E/SH2D1A/CD160/HLA-B/CD226/CADM1/VAV1/LEP/FAM49B/CXCL6/LILRB1	23
BP	GO:0002687	positive regulation of leukocyte migration	32/2112	128/18670	1.094e-05	0.0002196	0.0001586	CCL5/CXCL13/KITLG/XCL1/CCR2/RAC2/CCL19/ITGA4/CCR7/CD74/ICAM1/LGALS9/ADAM8/DYSF/PDGFD/TNFRSF14/GPSM3/CXCL10/THBS4/CXCL8/CCL21/CCR1/CAMK1D/PTN/NCKAP1L/CCL7/IL6/FPR2/ADAM10/VEGFB/IL1R1/PLA2G7	32
BP	GO:0043406	positive regulation of MAP kinase activity	53/2112	258/18670	1.129e-05	0.000226	0.0001633	KITLG/PTPRC/BMP4/IGF1/RASGRP1/CSK/PLCE1/FGF18/CXCR4/CCL19/TPD52L1/DUSP5/LPAR1/CD74/MAP3K11/NOD2/ADAM8/JAK2/PDGFD/CD40/HTR2B/MAP3K8/RIPK2/EGFR/FGF2/MAP4K1/CSPG4/GHR/ERBB2/CDK1/HGF/EZH2/CD40LG/NOX4/SOD1/FZD4/HTR2A/PTPN11/MAP3K2/FPR1/FLT3/PAK1/SYK/IKBKG/TGFB3/MAPKAPK2/AKAP13/DUSP6/NOD1/SHC2/CD81/TLR6/IL1B	53
BP	GO:0097553	calcium ion transmembrane import into cytosol	34/2112	140/18670	1.154e-05	0.0002288	0.0001653	CXCL9/CCR5/XCL1/LCK/PTPRC/CORO1A/PLCE1/CCL19/SRI/CACNA2D1/ANK2/CCR7/HTR2B/CXCL10/PTPN6/FGF2/PLCG2/CCL21/PLN/TRPC1/HTR2A/CD19/ATP1A2/CXCL11/SLC8A1/P2RY6/APLNR/DDIT3/RYR3/CYBA/LYN/PKD2/GSTO1/GSTM2	34
BP	GO:0031343	positive regulation of cell killing	21/2112	68/18670	1.155e-05	0.0002288	0.0001653	XCL1/PTPRC/PRF1/RASGRP1/HLA-F/HLA-A/HLA-C/HLA-G/MICB/CRTAM/HLA-E/CLEC7A/SH2D1A/CD160/HLA-B/CD226/CADM1/VAV1/IFNG/FAM49B/SYK	21
BP	GO:0033047	regulation of mitotic sister chromatid segregation	21/2112	68/18670	1.155e-05	0.0002288	0.0001653	TACC3/PTTG1/PTTG3P/BUB1/NDC80/MAD2L1/PLK1/TPR/DLGAP5/ZNF207/BUB1B/ATRX/CCNB1/FBXO5/NIPBL/CENPF/TTK/AURKB/RB1/CDC20/TRIP13	21
BP	GO:0060402	calcium ion transport into cytosol	37/2112	158/18670	1.18e-05	0.000233	0.0001684	CXCL9/CCR5/XCL1/LCK/PTPRC/CORO1A/PLCE1/CCL19/SRI/CACNA2D1/ANK2/CCR7/HTR2B/CXCL10/PTPN6/FGF2/PLCG2/CCL21/BAK1/PLN/MS4A1/TRPC1/HTR2A/CD19/ATP1A2/CXCL11/SLC8A1/P2RY6/APLNR/DDIT3/RYR3/CYBA/LYN/PKD2/GSTO1/GSTM2/PML	37
BP	GO:0002758	innate immune response-activating signal transduction	59/2112	298/18670	1.215e-05	0.0002392	0.0001729	TRAF3/PSMB9/RELB/TNFAIP3/S100A9/PSMB8/IRF1/BIRC3/TLR8/RFTN1/CLEC10A/FCN1/PSMB10/MYD88/SKP1/TLR2/IRF4/ITGB2/NOD2/IRF7/MALT1/TNIP2/CD36/IFIH1/CTSL/PSME1/RIPK2/TSPAN6/CREBBP/CLEC7A/PLCG2/CLEC4E/NFKBIA/TLR5/DDX58/PTPRS/NFKB1/ICAM3/CTSB/MFHAS1/UBE2D1/COLEC12/DDX60/CLEC4A/PAK1/SYK/GFI1/IKBKG/TNIP3/BTK/MAPKAPK2/PTPN22/NR1H3/CYBA/LYN/NOD1/HCK/RAB11FIP2/TLR6	59
BP	GO:0042092	type 2 immune response	14/2112	35/18670	1.238e-05	0.000243	0.0001756	XCL1/CCR2/IL27RA/IDO1/BATF/CD74/IL4R/NOD2/TBX21/CD86/IL6/IL18/CD81/NLRP3	14
BP	GO:0042100	B cell proliferation	26/2112	95/18670	1.29e-05	0.0002523	0.0001823	PTPRC/CTLA4/GPR183/IL7R/SASH3/CD74/CD40/TFRC/ADA/CD40LG/NCKAP1L/MS4A1/CD19/LEF1/MNDA/BTK/TNFRSF4/CD38/INPP5D/CD180/CD320/LYN/CD81/IFNA1/VAV3/CR2	26
BP	GO:1903038	negative regulation of leukocyte cell-cell adhesion	32/2112	129/18670	1.299e-05	0.0002528	0.0001827	PLA2G2D/XCL1/CTLA4/BMP4/IRF1/RUNX3/IDO1/DLG5/LILRB2/GLI3/CD74/PTPN2/IL4R/HLA-G/LGALS9/TNFRSF14/SOCS1/TWSG1/BTN2A2/PTPN6/CCL21/ERBB2/TBX21/PDCD1LG2/CD86/SOCS6/CD80/HFE/PTPN22/LRRC32/IL2RA/LILRB1	32
BP	GO:0050792	regulation of viral process	45/2112	208/18670	1.3e-05	0.0002528	0.0001827	CCL5/LAMP3/STAT1/CXCR4/FCN1/SLPI/NUCKS1/CD74/APOBEC3G/CHD1/OAS1/LGALS9/ISG20/PC/SRPK1/IFI27/OASL/CXCL8/CCNT1/SP1/FAM111A/TOP2A/LEF1/TRIM21/NOTCH1/FBXL2/GTF2F1/ADAR/MPHOSPH8/OAS3/POLR2L/TRIM38/IFIT5/CHMP2B/PLSCR1/CFL1/KPNA2/RSF1/TRIM26/MX1/ZC3HAV1/ISG15/GSN/PTX3/PML	45
BP	GO:0002218	activation of innate immune response	62/2112	319/18670	1.351e-05	0.0002618	0.0001892	TRAF3/AIM2/PSMB9/RELB/TNFAIP3/S100A9/PSMB8/IRF1/BIRC3/TLR8/RFTN1/CLEC10A/FCN1/PSMB10/MYD88/SKP1/TLR2/IRF4/ITGB2/NOD2/IRF7/MALT1/TNIP2/CD36/IFIH1/CTSL/PSME1/RIPK2/TSPAN6/CREBBP/CLEC7A/PLCG2/CLEC4E/NFKBIA/TLR5/DDX58/PTPRS/NFKB1/ICAM3/CTSB/MFHAS1/UBE2D1/COLEC12/HEXIM1/DDX60/MNDA/CLEC4A/PAK1/SYK/GFI1/IKBKG/TNIP3/BTK/MAPKAPK2/PTPN22/NR1H3/CYBA/LYN/NOD1/HCK/RAB11FIP2/TLR6	62
BP	GO:1903510	mucopolysaccharide metabolic process	29/2112	112/18670	1.355e-05	0.0002618	0.0001892	PRELP/NDNF/FMOD/SPOCK2/IL15/OGN/PIM1/CHST15/ANGPT1/HMMR/FGF2/CHST3/LYVE1/DCN/BGN/CSPG4/ITIH5/HGF/CHST11/LUM/NFKB1/VCAN/HYAL1/UGDH/IDUA/B3GNT2/STAB2/IL1B/B4GALT2	29
BP	GO:0001913	T cell mediated cytotoxicity	17/2112	49/18670	1.41e-05	0.0002708	0.0001956	XCL1/PTPRC/PRF1/HLA-F/HLA-A/IL7R/HLA-C/EMP2/HLA-G/CTSC/MICB/HLA-E/HLA-B/RAB27A/FAM49B/LILRB1/CTSH	17
BP	GO:0002448	mast cell mediated immunity	17/2112	49/18670	1.41e-05	0.0002708	0.0001956	RASGRP1/RAC2/LAT/IL4R/LGALS9/GATA2/FGR/S100A13/IL13RA2/PIK3CD/STXBP2/SYK/STXBP1/BTK/FER/GAB2/LYN	17
BP	GO:0032611	interleukin-1 beta production	27/2112	101/18670	1.418e-05	0.0002715	0.0001961	AIM2/TNFAIP3/IGF1/TLR8/CCL19/CCR7/LGALS9/NOD2/MALT1/JAK2/CD36/RIPK2/SPHK1/CLEC7A/CX3CR1/CASP1/SMAD3/MNDA/IFNG/SERPINB1/HSPB1/NOD1/PANX1/TLR6/IL1B/PML/NLRP3	27
BP	GO:0032673	regulation of interleukin-4 production	12/2112	27/18670	1.444e-05	0.0002756	0.0001992	CD3E/PRKCQ/SASH3/IRF4/LGALS9/HLA-E/CD40LG/CD86/CD83/LEF1/SYK/NLRP3	12
BP	GO:0051701	interaction with host	45/2112	209/18670	1.479e-05	0.0002813	0.0002032	CCR5/SLAMF1/ITGB7/CXCR4/FCN1/CD74/AXL/ICAM1/LGALS9/TNFRSF14/TFRC/EGFR/DAG1/PC/NPC1/CXCL8/CR1/CDK1/CD86/HTR2A/CTSB/TRIM21/HYAL1/SMAD3/THOC2/KRT6A/CD80/TNFRSF4/SCARB2/ANPEP/SELPLG/TRIM38/TYMS/CHMP2B/KPNA2/TRIM26/HIPK2/CD81/THOC1/ITGAV/THOC6/GSN/CR2/PTX3/PML	45
BP	GO:0043550	regulation of lipid kinase activity	20/2112	64/18670	1.524e-05	0.0002891	0.0002089	PIK3R1/CCL19/CCR7/NOD2/SOCS1/FGR/CISH/FGF2/CCL21/SOCS2/CD19/SOCS6/FLT3/PIK3R3/FPR2/RB1/PRKD1/LYN/CD81/VAV3	20
BP	GO:0006260	DNA replication	55/2112	274/18670	1.57e-05	0.000296	0.0002139	NFIC/LIG1/PURA/DTL/NUCKS1/PPP2CA/ZNF365/RRM2/BAZ1A/TTF1/EGFR/CDC45/BLM/E2F8/NFIB/ZBTB38/BARD1/CDK1/CCNA2/STAG2/TSPYL2/MCM5/FAM111A/ID3/REV3L/RFC3/ZPR1/GINS1/FEN1/RMI1/ATRX/TNFAIP1/DONSON/TIMELESS/CDC7/MCM2/PTMS/TERF1/DBF4/FBXO5/POLE2/RNASEH2A/CDK2AP1/CHAF1B/MCM4/HMGA1/GINS3/THOC1/SETMAR/TP53/CCNE2/NFIX/MCM10/TOPBP1/DNAJC2	55
BP	GO:0032386	regulation of intracellular transport	77/2112	423/18670	1.573e-05	0.000296	0.0002139	LCP1/PIK3R1/GAS1/BMP4/ZIC1/PTPN14/RAC2/GLI3/PREPL/PRKCB/ANGPT1/HCLS1/PFN2/ITGB1BP1/MX2/ITGB2/IL4R/LGALS9/CRYAB/CD36/GATA2/FGR/IFI27/CPSF6/TPR/BARD1/ERBB2/TCF7L2/NLGN1/IL13RA2/PLN/ZPR1/HTR2A/CHRNA5/SMAD3/YIPF5/EDEM1/PTPN11/FEZ1/ECT2/GDI1/LEP/IFNG/STX18/STXBP2/PAK1/MYO1C/ADIPOQ/SYK/ZFAND1/TRIM58/VAMP2/STXBP1/PINK1/BACE1/MAP1B/FER/UBE2J1/FERMT1/GAB2/LYN/HSPA1L/DVL1/KIF20B/CD81/EDEM2/SH3TC2/PRR5L/MTMR2/TP53/BNIP3L/KHDRBS1/CASK/IL1B/UBE2G2/P2RY4/XPO4	77
BP	GO:0097696	STAT cascade	38/2112	166/18670	1.575e-05	0.000296	0.0002139	CCL5/PTPRC/CRLF1/CCR2/IGF1/STAT1/IL15/IL7R/PPP2CA/PTPN2/HCLS1/CRLF3/JAK2/NMI/CD40/SOCS1/AKR1B1/STAT4/GHR/SOCS2/NOTCH1/LEP/IL6ST/IFNG/PECAM1/SOCS6/PRL/FLT3/IL10RA/CTF1/IL6/FER/IL18/LYN/SH2B3/PKD2/CCL2/IFNA1	38
BP	GO:0030198	extracellular matrix organization	69/2112	368/18670	1.587e-05	0.0002969	0.0002145	LCP1/NDNF/TNFRSF11B/FMOD/DDR2/TNFRSF1B/ITGB7/SPOCK2/ADAM19/DPT/SOX9/ITGA4/FOXC1/MMP1/NFKB2/ANTXR1/JAM3/MFAP4/ITGB2/HTRA1/KAZALD1/SULF1/ECM2/LAMA2/ICAM1/EFEMP2/ADAM8/ADAMTSL2/TIMP2/COMP/CTSL/FBLN5/RECK/COL8A2/SH3PXD2A/PDPN/DAG1/FGF2/DCN/BGN/ITGAL/COL8A1/COL14A1/SPINT2/LUM/ICAM3/VCAN/SMAD3/COL15A1/HSD17B12/NOTCH1/ITGA10/PECAM1/ITGAX/IL6/MYH11/FBLN1/RB1/FERMT1/ADAM10/CTRB2/KDR/CFLAR/SPINK5/ITGAV/COL16A1/ITGAE/MMP12/PTX3	69
BP	GO:0002221	pattern recognition receptor signaling pathway	43/2112	197/18670	1.594e-05	0.0002969	0.0002145	TRAF3/TNFAIP3/S100A9/IRF1/BIRC3/TLR8/RFTN1/FCN1/MYD88/TLR2/IRF4/ITGB2/NOD2/IRF7/TNIP2/CD36/IFIH1/CTSL/RIPK2/TSPAN6/CLEC7A/CLEC4E/NFKBIA/TLR5/DDX58/PTPRS/CTSB/MFHAS1/UBE2D1/COLEC12/DDX60/GFI1/IKBKG/TNIP3/BTK/MAPKAPK2/PTPN22/NR1H3/CYBA/LYN/NOD1/RAB11FIP2/TLR6	43
BP	GO:1904950	negative regulation of establishment of protein localization	43/2112	197/18670	1.594e-05	0.0002969	0.0002145	SFRP1/TNFAIP3/GBP1/IL27RA/CSK/TLR8/RHBDF2/PPP3CA/CD200/ANGPT1/ITGB1BP1/CD36/BTN2A2/SRGN/KLF7/IDH2/BARD1/RHBDF1/PTPN11/CORO2B/GDI1/PPM1F/PTGER4/TERF1/ADIPOQ/SERPINB1/TNFRSF4/PTPN22/ANXA4/NR1H3/UBE2J1/FERMT1/PPP1R11/NDFIP1/HADH/LRRC32/TLR6/IL1B/UBE2G2/PML/RAB11FIP1/LILRB1/NLRP3	43
BP	GO:0002793	positive regulation of peptide secretion	57/2112	288/18670	1.712e-05	0.0003179	0.0002297	AIM2/CD2/IGF1/RASGRP1/TLR8/MYH10/FCN1/CCL19/SRI/OXCT1/ABCG1/TLR2/IL4R/LGALS9/NOD2/ADAM8/WLS/JAK2/IFIH1/ITSN1/HTR2B/TNFRSF14/RIPK2/FGR/CRTAM/EGFR/HLA-E/TM7SF3/MPC2/CD160/CLEC4E/AKAP12/TCF7L2/CADM1/DDX58/CASP1/RBP4/IFNG/OR51E2/PTGER4/STX4/SYK/HFE/TGFB3/TNFRSF4/IL6/PTPN22/CD38/SYBU/FERMT1/ANG/PANX1/SPTBN1/IL1B/MMP12/GPR27/NLRP3	57
BP	GO:0052547	regulation of peptidase activity	81/2112	452/18670	1.727e-05	0.0003196	0.0002309	LAMP3/AIM2/PSMB9/SERPINA1/LCK/S100A9/PSMB8/TNFAIP8/BIRC3/TIMP3/SPOCK2/CST7/SERPINA3/SERPINA5/SLPI/PTTG1/PCOLCE2/SPOCK1/ANTXR1/BID/TNFSF10/TIMP4/LGALS9/MALT1/CRYAB/JAK2/TIMP2/PSME1/RIPK2/RPS6KA1/RECK/DLC1/PROS1/DAP/CASP10/CLEC7A/CR1/UBE2Z/SPINT2/ITIH5/BAK1/HGF/SOX2/ASPH/CD27/TP63/NDUFA13/ARL6IP5/PCOLCE/PEBP1/CASP1/PMAIP1/LEF1/ADRM1/CYFIP2/SMAD3/FAM162A/VCP/CASP5/SERPINI1/MICAL1/PPM1F/LXN/SYK/SERPINB1/PINK1/APAF1/RCN3/FBLN1/APLP2/TFPI/LYN/NOD1/NLE1/CFLAR/SPINK5/CASP4/GSN/PML/CTSH/NLRP3	81
BP	GO:0048771	tissue remodeling	40/2112	179/18670	1.745e-05	0.0003221	0.0002327	SFRP1/TNFAIP3/CCR2/GDF5/IGFBP5/LRP6/TNFRSF11B/CSK/RAC2/IL15/LTBP3/FOXC1/PPP3CA/AXL/TCIRG1/ADAM8/TFRC/EGFR/THBS4/BGN/CSPG4/BAK1/PTN/LRP5/NOX4/CA2/LEP/SYK/PDK4/TGFB3/IL6/CD38/INPP5D/IL18/SNX10/MERTK/S1PR1/PTH1R/TGM2/TP53	40
BP	GO:0002820	negative regulation of adaptive immune response	16/2112	45/18670	1.763e-05	0.0003245	0.0002344	XCL1/PTPRC/IL27RA/HLA-F/IL7R/IL4R/HLA-G/SAMSN1/TNFRSF14/PTPN6/CR1/CD160/TBX21/HFE/THOC1/LILRB1	16
BP	GO:0001659	temperature homeostasis	39/2112	173/18670	1.786e-05	0.0003277	0.0002367	FTO/CCR2/HOXC10/CXCR4/IL15/ACADVL/IRF4/IL4R/DIO2/NOVA1/JAK2/CD36/PLAC8/TRPV2/PER2/HTR2A/FOXO1/NOTCH1/ARNTL/LEP/ADIPOQ/SYK/FABP5/EDNRB/G0S2/DDIT3/NR1H3/UCP2/RB1/IL18/FABP4/ABHD6/ACADL/HADH/NPR3/PRKAB1/YBX2/IL1B/THRA	39
BP	GO:0007422	peripheral nervous system development	22/2112	75/18670	1.796e-05	0.0003286	0.0002374	RUNX3/NTRK2/SKI/ALDH3A2/PARD3/GSTM3/LAMA2/DAG1/PMP22/ERBB2/CDK1/FA2H/SOD1/ARHGEF10/ADAM22/MYOC/SERPINI1/SLC5A3/EDNRB/HOXD10/MPP5/SH3TC2	22
BP	GO:0045841	negative regulation of mitotic metaphase/anaphase transition	14/2112	36/18670	1.816e-05	0.0003312	0.0002393	BUB1/NDC80/MAD2L1/PLK1/TPR/ZNF207/BUB1B/CCNB1/FBXO5/CENPF/TTK/AURKB/CDC20/TRIP13	14
BP	GO:0043254	regulation of protein complex assembly	83/2112	467/18670	1.867e-05	0.0003393	0.0002452	CXCL13/LCP1/AIM2/CORO1A/CLU/ADD3/ARPIN/TMOD1/MMP1/TPPP3/CCR7/COTL1/BID/HCLS1/PFN2/RASIP1/ICAM1/CRYAB/CD36/WASL/TMSB10/CLEC7A/TAF7/HJURP/CCL21/WAS/CDC42EP3/PLEK/TUBB4A/NCKAP1L/GMFG/SKAP1/PMEPA1/VPS16/PMAIP1/VASP/ARPC5L/PTPN11/LDLRAD4/VCP/KANK1/IFNG/LMOD1/MECP2/HEY2/PTGER4/TERF1/PAK1/MYO1C/DACT1/SYK/FOSL1/PARP1/STXBP1/CAMSAP2/CRBN/CTTN/PINK1/MAP1B/FER/CAPZA1/VILL/AP1AR/RB1/GFAP/CLIP3/CUL4B/HCK/ARPC1A/ERCC1/ATXN2/ABI2/ACTR3/PFN1/TP53/IQGAP2/SPTBN1/GSN/TLR6/CDH5/ACTR2/THRA/GTF2H5	83
BP	GO:1903900	regulation of viral life cycle	35/2112	149/18670	1.871e-05	0.0003393	0.0002452	CCL5/LAMP3/FCN1/SLPI/NUCKS1/CD74/APOBEC3G/OAS1/LGALS9/ISG20/PC/SRPK1/IFI27/OASL/CXCL8/FAM111A/TOP2A/TRIM21/NOTCH1/FBXL2/ADAR/MPHOSPH8/OAS3/TRIM38/IFIT5/CHMP2B/PLSCR1/KPNA2/TRIM26/MX1/ZC3HAV1/ISG15/GSN/PTX3/PML	35
BP	GO:0042035	regulation of cytokine biosynthetic process	29/2112	114/18670	1.951e-05	0.0003526	0.0002548	CD3E/PTPRC/CCR2/IRF1/TLR8/PRKCQ/INHBA/IRF4/CD74/LTB/IGF2BP3/JAK2/NMI/CLEC7A/AKAP12/CX3CR1/NFKB1/CD86/IFNG/SYK/CD80/HSPB1/MAPKAPK2/IL6/INPP5D/UBE2J1/TLR6/IL1B/LILRB1	29
BP	GO:0043551	regulation of phosphatidylinositol 3-kinase activity	18/2112	55/18670	1.99e-05	0.000358	0.0002586	PIK3R1/CCL19/CCR7/NOD2/SOCS1/FGR/CISH/FGF2/CCL21/SOCS2/CD19/SOCS6/FLT3/PIK3R3/FPR2/PRKD1/LYN/VAV3	18
BP	GO:0002294	CD4-positive, alpha-beta T cell differentiation involved in immune response	19/2112	60/18670	2.005e-05	0.000358	0.0002586	RELB/SEMA4A/GPR183/CCL19/BATF/IRF4/IL4R/LGALS9/MALT1/RIPK2/TBX21/CD86/LEF1/IFNG/PTGER4/CD80/IL6/IL18/NLRP3	19
BP	GO:0051306	mitotic sister chromatid separation	19/2112	60/18670	2.005e-05	0.000358	0.0002586	TACC3/PTTG1/PTTG3P/BUB1/NDC80/MAD2L1/PLK1/TPR/DLGAP5/ZNF207/BUB1B/CCNB1/FBXO5/CENPF/TTK/AURKB/RB1/CDC20/TRIP13	19
BP	GO:0051784	negative regulation of nuclear division	19/2112	60/18670	2.005e-05	0.000358	0.0002586	BMP4/PTTG1/PTTG3P/BUB1/NDC80/MAD2L1/PLK1/TPR/ZNF207/BUB1B/TOM1L1/ATRX/CCNB1/FBXO5/CENPF/TTK/AURKB/CDC20/TRIP13	19
BP	GO:0045059	positive thymic T cell selection	8/2112	13/18670	2.015e-05	0.000358	0.0002586	CD3D/CD3E/PTPRC/CD74/PTPN2/CD3G/ZAP70/DOCK2	8
BP	GO:0045086	positive regulation of interleukin-2 biosynthetic process	8/2112	13/18670	2.015e-05	0.000358	0.0002586	CD3E/PTPRC/PRKCQ/IRF4/CLEC7A/CD86/CD80/IL1B	8
BP	GO:0097048	dendritic cell apoptotic process	7/2112	10/18670	2.066e-05	0.0003649	0.0002637	CCL19/CCR7/AXL/LGALS9/CCL21/LYN/LILRB1	7
BP	GO:2000668	regulation of dendritic cell apoptotic process	7/2112	10/18670	2.066e-05	0.0003649	0.0002637	CCL19/CCR7/AXL/LGALS9/CCL21/LYN/LILRB1	7
BP	GO:0002577	regulation of antigen processing and presentation	10/2112	20/18670	2.122e-05	0.0003738	0.0002701	LILRB2/CCL19/CCR7/CD74/NOD2/CCL21/WAS/TAPBPL/HFE/NOD1	10
BP	GO:1901653	cellular response to peptide	71/2112	385/18670	2.137e-05	0.0003754	0.0002712	ENPP1/PID1/PIK3R1/IGF1/CSK/STAT1/PTPRE/PRKCQ/ITGA4/SH2B2/CACNA2D1/NUCKS1/RAB8A/PRKCB/PTPN2/TCIRG1/ICAM1/NOD2/JAK2/CD36/SOCS1/RIPK2/AKR1B1/CISH/CPEB1/GHR/AHCYL1/SP1/CCNA2/SOCS2/PCK1/BCL2L2/ZNF106/NFKB1/FOXO1/PTPN11/CA2/KL/KANK1/LEP/TIMELESS/ZFP36L1/AGTR1/PIK3CA/PRL/PAK1/MYO1C/ADIPOQ/PDK4/SORBS1/PARP1/VAMP2/BACE1/PIK3R3/MAP1B/PTPN22/FER/LDOC1/FOXO3/FPR2/CYBA/LYN/NOD1/PDE3B/CFLAR/IRS4/CASP4/TP53/ATP6V1B2/TLR6/IL1B	71
BP	GO:0050673	epithelial cell proliferation	78/2112	434/18670	2.212e-05	0.0003865	0.0002792	CCL5/SFRP1/TNFAIP3/GDF5/BMP4/BCL11B/IGFBP5/RUNX3/CDKN1C/IGF1/STAT1/SOX9/PURA/ITGA4/FGF7/ITGB1BP1/HTRA1/AR/SULF1/SIX1/NOD2/BMPR1A/DYSF/PRKD2/HTR2B/SCG2/YAP1/GATA2/RPS6KA1/EGFR/COL8A2/FGF2/TGFBR3/THBS4/NFIB/COL8A1/ERBB2/HGF/SP1/TCF7L2/SOX2/PPP1R16B/PTN/TP63/BCL2L2/HYAL1/SMAD3/TNMD/FZD7/NOTCH1/LEP/ZFP36L1/AGTR1/ARNT/RGN/OR51E2/PRL/CCND1/APLNR/EDNRB/FGF9/SERPINB1/AKT3/RB1/FERMT1/CYBA/VEGFB/PRKD1/ANG/KDR/CFLAR/CCL2/EAF2/CASK/LIMS2/MMP12/HOXA5/THAP1	78
BP	GO:0007160	cell-matrix adhesion	47/2112	225/18670	2.213e-05	0.0003865	0.0002792	PIK3R1/CD3E/SFRP1/EPHA3/LIMCH1/DDR2/TMEM8B/ITGB7/ITGA4/CCR7/JAM3/EMP2/ITGB1BP1/ITGB2/ECM2/FERMT2/CD36/CD96/FBLN5/DAG1/ITGBL1/DLC1/LYVE1/ITGAL/CCL21/SGCE/SKAP1/EFNA5/SMAD3/CORO2B/MYOC/ITGA10/TIMM10B/PECAM1/PPM1F/TRIP6/PLEKHA2/SORBS1/CTTN/RHOD/FERMT1/SEMA3E/KDR/ITGAV/CASK/COL16A1/MMP12	47
BP	GO:0022408	negative regulation of cell-cell adhesion	40/2112	181/18670	2.294e-05	0.0003996	0.0002887	PLA2G2D/XCL1/CTLA4/BMP4/IRF1/RUNX3/IDO1/DLG5/LILRB2/GLI3/CD74/PTPN2/IL4R/HLA-G/LGALS9/JAK2/TNFRSF14/SOCS1/TWSG1/BTN2A2/PTPN6/CCL21/ERBB2/SPINT2/TBX21/PDCD1LG2/CD86/CD9/SOCS6/PPM1F/ADIPOQ/CD80/HFE/PTPN22/PRKG1/IL1RN/SH2B3/LRRC32/IL2RA/LILRB1	40
BP	GO:0002407	dendritic cell chemotaxis	11/2112	24/18670	2.314e-05	0.0004007	0.0002895	CCL5/SLAMF8/CCR5/CCR2/CXCR4/GPR183/CCL19/CCR7/LGALS9/CCL21/CCR1	11
BP	GO:0090023	positive regulation of neutrophil chemotaxis	11/2112	24/18670	2.314e-05	0.0004007	0.0002895	XCL1/RAC2/CCL19/CCR7/CD74/DYSF/THBS4/CXCL8/CCL21/CAMK1D/NCKAP1L	11
BP	GO:0033628	regulation of cell adhesion mediated by integrin	16/2112	46/18670	2.421e-05	0.000417	0.0003013	CCL5/CXCL13/CD3E/LPXN/ITGB1BP1/ADA/PTPN6/CCL21/NCKAP1L/SKAP1/PTPN11/SYK/TESC/FERMT1/LYN/PDE3B	16
BP	GO:0043300	regulation of leukocyte degranulation	16/2112	46/18670	2.421e-05	0.000417	0.0003013	CCR2/HLA-F/RAC2/ITGB2/IL4R/LGALS9/GATA2/FGR/IL13RA2/STXBP2/STX4/SYK/STXBP1/FER/GAB2/LYN	16
BP	GO:0051495	positive regulation of cytoskeleton organization	47/2112	226/18670	2.492e-05	0.0004281	0.0003093	SFRP1/LIMCH1/CORO1A/ARPIN/CCR7/LPAR1/HCLS1/PFN2/ITGB1BP1/ICAM1/WASL/TAC1/CCL21/WAS/CDC42EP3/PLEK/NOX4/NCKAP1L/GMFG/ARHGEF10/DSTN/SMAD3/VASP/ARPC5L/GPR65/MYOC/LMOD1/MECP2/PPM1F/TERF1/PAK1/MYO1C/TGFB3/CTTN/MAP1B/FER/CFL1/AP1AR/HCK/ARPC1A/WDR1/ABI2/ACTR3/PFN1/IQGAP2/GSN/ACTR2	47
BP	GO:0051098	regulation of binding	69/2112	373/18670	2.503e-05	0.0004287	0.0003097	GZMA/BMP4/IGF1/ITGA4/SRI/SLPI/FOXC1/SKI/NUCKS1/PPP2CA/PPP3CA/CDON/IRF4/ANGPT1/ITGB1BP1/JAK2/PCBD1/GOLGA2/PLK1/CD36/HDAC4/RIPK2/TGFBR3/DZIP1/SPON1/HJURP/SMARCD3/BAG2/BAK1/EIF3E/LARP6/TCF7L2/PLN/ID3/PER2/NFKBIA/PTPRF/CCPG1/NEK2/PPP2CB/LRPAP1/LEF1/SMAD3/PLK2/GTF2F1/IFNG/PPP1CA/HEY2/HSP90AB1/ADIPOQ/DACT1/PARP1/PEX19/HFE/CRBN/NIPBL/DDIT3/LDOC1/AURKB/RSF1/RB1/CRTAC1/HIPK2/HEY1/DVL1/IFIT2/PIM2/CCL23/AURKA	69
BP	GO:0002287	alpha-beta T cell activation involved in immune response	19/2112	61/18670	2.605e-05	0.0004432	0.0003203	RELB/SEMA4A/GPR183/CCL19/BATF/IRF4/IL4R/LGALS9/MALT1/RIPK2/TBX21/CD86/LEF1/IFNG/PTGER4/CD80/IL6/IL18/NLRP3	19
BP	GO:0002293	alpha-beta T cell differentiation involved in immune response	19/2112	61/18670	2.605e-05	0.0004432	0.0003203	RELB/SEMA4A/GPR183/CCL19/BATF/IRF4/IL4R/LGALS9/MALT1/RIPK2/TBX21/CD86/LEF1/IFNG/PTGER4/CD80/IL6/IL18/NLRP3	19
BP	GO:0001933	negative regulation of protein phosphorylation	77/2112	429/18670	2.609e-05	0.0004432	0.0003203	ENPP1/PID1/CDKN2C/SFRP1/PTPRC/TNFAIP3/BMP4/GBP1/UCHL1/LRP6/CDKN1C/CSK/TIMP3/LMO3/SEMA4D/SH3BP5/PARD3/PPP2CA/DUSP5/ANGPT1/PTPN2/ITGB1BP1/RASIP1/SAMSN1/PLK1/SOCS1/DEPTOR/BTN2A2/UBE2B/GPRC5A/DAG1/PTPN6/TAF7/BAK1/HGF/ZGPAT/LRP5/GMFG/PMEPA1/PEBP1/FOXO1/PTPN13/LDLRAD4/ZMYND11/HEXIM1/IFNG/CCNB1/RGN/ADAR/MICAL1/PPM1F/ADIPOQ/DACT1/MBIP/HSPB1/CEP85/PINK1/WWTR1/PTPN22/IPO7/DUSP6/DUSP2/TESC/FBLN1/RB1/FABP4/LYN/GFRA2/CEBPA/SH2B3/DVL1/PRR5L/PBK/MVP/NDRG2/IL1B/GPD1L	77
BP	GO:1902100	negative regulation of metaphase/anaphase transition of cell cycle	14/2112	37/18670	2.618e-05	0.0004436	0.0003205	BUB1/NDC80/MAD2L1/PLK1/TPR/ZNF207/BUB1B/CCNB1/FBXO5/CENPF/TTK/AURKB/CDC20/TRIP13	14
BP	GO:0006650	glycerophospholipid metabolic process	61/2112	319/18670	2.633e-05	0.0004448	0.0003214	PLA2G2D/PLEKHA1/CPNE3/PIK3R1/PIGK/SERINC3/LPCAT3/CHPT1/PIP4K2B/HTR2B/SOCS1/CISH/PNPLA6/FGF2/SH3YL1/DPM3/PLCG2/PLEK/GPAA1/PLD1/MTMR14/ETNK1/SOCS2/PLA2G12A/PIK3CD/PIGH/PLEKHA4/PLA2G4C/HTR2A/INPP1/PTPN13/SOCS6/DGKA/PIK3CA/MECP2/PLA1A/SERINC1/PIGP/PRDX6/FABP5/PLEKHA2/CETP/PIK3R3/INPP5D/PTDSS1/PLSCR1/PIP4K2A/FPR2/STARD7/ABHD6/PIGT/PIGF/MTMR2/LIPC/MBOAT7/RAB14/PLA2G7/BPNT1/ALDH5A1/GPD1L/HADHA	61
BP	GO:2000377	regulation of reactive oxygen species metabolic process	42/2112	195/18670	2.782e-05	0.0004686	0.0003386	PID1/CLU/GCH1/RAC2/AKR1C3/HBB/ITGB2/ICAM1/CRYAB/JAK2/CD36/HDAC4/SLC18A2/EGFR/FBLN5/DDAH2/CLEC7A/CX3CR1/NOX4/SOD1/FOXO1/SMAD3/RAB27A/LEP/AGTR1/IFNG/RGN/TFAP2A/HSP90AB1/SYK/PINK1/HP/GLA/FOXO3/FPR2/CYBA/PKD2/CFLAR/TP53/TLR6/IL1B/PTX3	42
BP	GO:0030838	positive regulation of actin filament polymerization	26/2112	99/18670	2.844e-05	0.0004778	0.0003452	CORO1A/ARPIN/CCR7/PFN2/ICAM1/WASL/CCL21/WAS/CDC42EP3/NCKAP1L/GMFG/VASP/ARPC5L/LMOD1/MYO1C/CTTN/FER/AP1AR/HCK/ARPC1A/ABI2/ACTR3/PFN1/IQGAP2/GSN/ACTR2	26
BP	GO:0072001	renal system development	57/2112	293/18670	2.874e-05	0.0004816	0.000348	SFRP1/CRLF1/BMP4/CDKN1C/DLG5/PLCE1/STAT1/SOX9/ZBTB16/GLI3/FOXC1/ANGPT1/SULF1/KANK2/SGPL1/SIX1/NUP93/PDGFD/SIX2/YAP1/AKR1B1/FGF2/DCN/CEP55/MAGI2/ACAT1/ID3/NUP160/PBX1/DCHS1/SMAD3/CA2/RBP4/NOTCH1/AGTR1/RGN/PECAM1/TFAP2A/ADIPOQ/NIPBL/WWTR1/CENPF/APAF1/FAT4/EMX2/FSTL3/PKD2/NLE1/CFLAR/REN/CAT/ARL3/POU3F3/HOXA11/GPR4/CTSH/AHI1	57
BP	GO:0032273	positive regulation of protein polymerization	32/2112	134/18670	2.957e-05	0.0004937	0.0003567	CORO1A/ARPIN/TPPP3/CCR7/PFN2/ICAM1/WASL/CCL21/WAS/CDC42EP3/NCKAP1L/GMFG/VASP/ARPC5L/LMOD1/MECP2/TERF1/PAK1/MYO1C/CTTN/PINK1/MAP1B/FER/AP1AR/HCK/ARPC1A/ABI2/ACTR3/PFN1/IQGAP2/GSN/ACTR2	32
BP	GO:0002224	toll-like receptor signaling pathway	34/2112	146/18670	2.963e-05	0.0004937	0.0003567	TRAF3/TNFAIP3/S100A9/IRF1/BIRC3/TLR8/RFTN1/MYD88/TLR2/IRF4/ITGB2/IRF7/TNIP2/CD36/CTSL/RIPK2/NFKBIA/TLR5/PTPRS/CTSB/MFHAS1/UBE2D1/COLEC12/GFI1/IKBKG/TNIP3/BTK/MAPKAPK2/PTPN22/NR1H3/CYBA/LYN/RAB11FIP2/TLR6	34
BP	GO:0031643	positive regulation of myelination	9/2112	17/18670	3.098e-05	0.000515	0.0003721	WASF3/TNFRSF1B/CST7/PARD3/DAG1/HGF/ITGAX/TENM4/RNF10	9
BP	GO:0070374	positive regulation of ERK1 and ERK2 cascade	45/2112	215/18670	3.111e-05	0.0005157	0.0003726	CCL5/XCL1/PTPRC/BMP4/SLAMF1/RASGRP1/FGF18/GPR183/CCL19/CCL13/CCR7/ANGPT1/CD74/ICAM1/LGALS9/ACKR3/NOD2/CD36/PDGFD/PRKD2/HTR2B/RIPK2/EGFR/FGF2/CCL21/AKAP12/CCR1/NOX4/CCL18/HTR2A/PTPN11/MFHAS1/NOTCH1/FLT3/CCL7/P2RY6/HCRTR1/PTPN22/FPR2/NOD1/KDR/CFLAR/CCL17/CCL2/CCL23	45
BP	GO:0045646	regulation of erythrocyte differentiation	16/2112	47/18670	3.288e-05	0.0005436	0.0003927	RBFOX2/STAT1/INHBA/GATA2/NCKAP1L/P4HTM/ZFP36L1/ARNT/TRIM58/SPI1/INPP5D/FOXO3/LYN/PRMT1/ISG15/HOXA5	16
BP	GO:0045453	bone resorption	19/2112	62/18670	3.362e-05	0.0005528	0.0003994	TNFAIP3/TNFRSF11B/CSK/RAC2/LTBP3/TCIRG1/ADAM8/TFRC/EGFR/NOX4/CA2/SYK/PDK4/IL6/CD38/INPP5D/SNX10/S1PR1/PTH1R	19
BP	GO:1905818	regulation of chromosome separation	19/2112	62/18670	3.362e-05	0.0005528	0.0003994	TACC3/PTTG1/PTTG3P/BUB1/NDC80/MAD2L1/PLK1/TPR/DLGAP5/ZNF207/BUB1B/CCNB1/FBXO5/CENPF/TTK/AURKB/RB1/CDC20/TRIP13	19
BP	GO:0032731	positive regulation of interleukin-1 beta production	17/2112	52/18670	3.417e-05	0.0005592	0.000404	AIM2/TLR8/CCL19/LGALS9/NOD2/MALT1/JAK2/RIPK2/CLEC7A/CASP1/SMAD3/MNDA/IFNG/HSPB1/NOD1/PANX1/NLRP3	17
BP	GO:0050864	regulation of B cell activation	40/2112	184/18670	3.418e-05	0.0005592	0.000404	SLAMF8/TRBC1/SFRP1/PTPRC/CTLA4/TNFAIP3/IL27RA/GPR183/INHBA/SASH3/CD74/NOD2/TNIP2/SAMSN1/CD40/TFRC/ADA/PTPN6/IGHM/IGLL5/TBX21/CD27/NCKAP1L/CD19/ZFP36L1/MNDA/IGLC1/SYK/BTK/TNFRSF4/IL6/CD38/IGHG1/INPP5D/CD320/LYN/CD81/ZFP36L2/THOC1/VAV3	40
BP	GO:0042326	negative regulation of phosphorylation	82/2112	468/18670	3.533e-05	0.0005755	0.0004158	ENPP1/PID1/CDKN2C/SFRP1/PTPRC/TNFAIP3/BMP4/GBP1/UCHL1/LRP6/CDKN1C/CSK/TIMP3/LMO3/SEMA4D/SH3BP5/INHBA/PARD3/PPP2CA/DUSP5/ANGPT1/PTPN2/ITGB1BP1/CBFA2T3/RASIP1/SAMSN1/PLK1/HDAC4/SOCS1/DEPTOR/BTN2A2/UBE2B/GPRC5A/DAG1/PTPN6/TAF7/BAK1/HGF/RHOH/ZGPAT/LRP5/GMFG/COX11/PMEPA1/PEBP1/FOXO1/PTPN13/LDLRAD4/ZMYND11/HEXIM1/IFNG/CCNB1/RGN/ADAR/MICAL1/PPM1F/ADIPOQ/DACT1/MBIP/HSPB1/CEP85/PINK1/WWTR1/PTPN22/IPO7/DUSP6/DUSP2/TESC/FBLN1/RB1/FABP4/LYN/GFRA2/CEBPA/SH2B3/DVL1/PRR5L/PBK/MVP/NDRG2/IL1B/GPD1L	82
BP	GO:0032535	regulation of cellular component size	68/2112	370/18670	3.537e-05	0.0005755	0.0004158	CORO1A/SEMA4A/ADD3/ARPIN/IL7R/TMOD1/SEMA4D/SEMA3A/CCR7/COTL1/HCLS1/PFN2/ICAM1/WASL/TMSB10/DEPTOR/FGF13/TRPV2/CCL21/WAS/CDC42EP3/PLEK/NCKAP1L/GMFG/RYK/PTPRS/SEMA3F/DSTN/EFNA5/VASP/ARPC5L/VAV1/GDI1/KANK1/LMOD1/PPP1CA/SLC12A2/HSP90AB1/PAK1/MYO1C/SLC12A8/CTTN/AKT3/MAP1B/ARHGAP4/MEGF8/FER/DPYSL2/CFL1/SEMA4F/CAPZA1/VILL/AP1AR/SEMA3E/SLC12A7/HCK/ARPC1A/WDR1/SEMA6B/ABI2/ACTR3/PFN1/HP1BP3/IQGAP2/SPTBN1/GSN/VAV3/ACTR2	68
BP	GO:0034599	cellular response to oxidative stress	58/2112	302/18670	3.613e-05	0.0005863	0.0004236	PLEKHA1/TNFAIP3/PENK/GCH1/NQO1/VRK2/AKR1C3/NFE2L1/AXL/SIGMAR1/MSRB2/OXR1/JAK2/CD36/PDGFD/EGFR/FBLN5/MELK/ETV5/SPHK1/LANCL1/CDK1/HGF/CCNA2/EZH2/NCF4/NOX4/SOD1/MAPK13/ARL6IP5/GPX3/FOXO1/NET1/ARNTL/ECT2/ARNT/RGN/PRDX6/PARP1/HSPB1/PINK1/BTK/IL6/FER/FOXO3/CYBA/PRKD1/RWDD1/PKD2/BAG5/FUT8/CFLAR/CAT/NCF1/PRR5L/TP53/TLR6/PML	58
BP	GO:0098813	nuclear chromosome segregation	52/2112	262/18670	3.633e-05	0.0005877	0.0004246	TACC3/PTTG1/PTTG3P/BUB1/NUSAP1/NCAPD2/NDC80/MAD2L1/PLK1/GEM/UBE2B/CDCA8/NCAPH/KIF18B/NCAPG/TPR/DLGAP5/ZNF207/STAG2/BUB1B/KIF2C/KIF4A/TOP2A/PRC1/NEK2/FEN1/RMI1/ATRX/RACGAP1/ECT2/ZWINT/STAG3/CCNB1/TERF1/FBXO5/NIPBL/CENPF/REC8/TTK/CHMP2B/AURKB/RB1/CDC20/TUBG2/SMC4/ACTR3/TRIP13/CCNE2/KIFC1/ACTR2/CHMP1B/KIF23	52
BP	GO:0045061	thymic T cell selection	10/2112	21/18670	3.641e-05	0.0005877	0.0004246	CD3D/CD3E/PTPRC/GLI3/CCR7/CD74/PTPN2/CD3G/ZAP70/DOCK2	10
BP	GO:0002507	tolerance induction	11/2112	25/18670	3.71e-05	0.0005968	0.0004312	CD3E/TNFAIP3/IDO1/LILRB2/HLA-G/LGALS9/HLA-E/ICOS/PHLPP1/LYN/IL2RA	11
BP	GO:0002707	negative regulation of lymphocyte mediated immunity	14/2112	38/18670	3.716e-05	0.0005968	0.0004312	XCL1/PTPRC/HLA-F/IL7R/HLA-G/LGALS9/CD96/HLA-E/PTPN6/CR1/TBX21/HFE/THOC1/LILRB1	14
BP	GO:0006066	alcohol metabolic process	67/2112	364/18670	3.83e-05	0.0006134	0.0004432	GK/LBR/IGF1/GCH1/PLCE1/APOL1/ALDH3A2/AKR1C3/ACADVL/ADH1C/ABCG1/NFE2L1/PMVK/DYSF/PCBD1/AKR1B1/CYB5R3/DHRS3/FGF2/AKR1C1/SPHK1/NPC1/PLCG2/PLEK/ERLIN1/SP1/SCARF1/PCK1/SOD1/ACACB/NFKB1/INPP1/SC5D/HRH1/RBP4/LEP/IFNG/MECP2/NUDT11/ADH1B/SLC5A3/NFYA/P2RY6/ERLIN2/GFI1/CETP/PPIP5K1/ADH5/INPP5D/HDLBP/DHRS9/OSBPL1A/MBTPS2/RETSAT/CYP46A1/CEBPA/ACADL/NAAA/DKK3/CAT/PTH1R/MTMR2/LIPC/AKR7A2/IL1B/EPHX2/SOAT2	67
BP	GO:0007265	Ras protein signal transduction	79/2112	448/18670	3.89e-05	0.0006215	0.0004491	KITLG/IGF1/RASGRP1/RAC2/PLCE1/ARHGDIB/RALGDS/CYTH1/SH2B2/LAT/RAB8A/RASGRP3/ARHGEF18/LPAR1/RHOBTB3/AUTS2/MAPRE2/RASIP1/KANK2/ARHGEF9/JAK2/ARHGEF26/ITSN1/RHOF/TIMP2/PDPN/DLC1/FGF2/GPR18/RAB40B/DENND1A/WAS/CDC42EP3/RHOH/CCNA2/PLD1/RAB33B/ARHGEF3/ARHGEF10/PPP2CB/RRAS/RAB20/DNMT1/ARHGEF12/NET1/PSD3/RAB27A/VAV1/TNFAIP1/GPR65/RASA2/PLK2/NOTCH1/MYOC/ECT2/GDI1/KANK1/RHOG/AGTR1/CYTH4/PECAM1/PSD4/RAB28/RHOD/AKAP13/ARHGAP4/CFL1/RB1/PRKD1/DENND4B/LYN/SHC2/WASF2/ABI2/TP53/GPR4/RAB14/VAV3/SCAI	79
BP	GO:1903532	positive regulation of secretion by cell	72/2112	399/18670	3.936e-05	0.0006272	0.0004531	AIM2/CD2/IGF1/RASGRP1/TLR8/HLA-F/MYH10/FCN1/CCL19/SRI/INHBA/OXCT1/ABCG1/TLR2/ITGB2/IL4R/LGALS9/NOD2/ADAM8/WLS/JAK2/IFIH1/ITSN1/HTR2B/TNFRSF14/GATA2/RIPK2/FGR/CRTAM/EGFR/HLA-E/TM7SF3/TAC1/MPC2/CD160/NMB/CLEC4E/AKAP12/TCF7L2/NLGN1/CADM1/DDX58/CASP1/RAB27A/PTPN11/RBP4/LEP/IFNG/KMO/OR51E2/PTGER4/STX4/SYK/STXBP1/HFE/TGFB3/PINK1/TNFRSF4/IL6/PTPN22/CD38/SYBU/FERMT1/GAB2/ANG/PANX1/SPTBN1/IL1B/MMP12/CADPS/GPR27/NLRP3	72
BP	GO:0043405	regulation of MAP kinase activity	63/2112	337/18670	3.997e-05	0.0006353	0.000459	KITLG/SFRP1/PTPRC/BMP4/UCHL1/IGF1/RASGRP1/CSK/PLCE1/FGF18/CXCR4/CCL19/TPD52L1/PPP2CA/DUSP5/LPAR1/CD74/MAP3K11/NOD2/ADAM8/JAK2/PDGFD/CD40/HTR2B/MAP3K8/RIPK2/EGFR/PTPN6/FGF2/MAP4K1/CSPG4/GHR/ERBB2/CDK1/HGF/EZH2/CD40LG/NOX4/SOD1/FZD4/HTR2A/PTPN11/MAP3K2/FPR1/FLT3/PAK1/ADIPOQ/SYK/MBIP/IKBKG/TGFB3/MAPKAPK2/AKAP13/PTPN22/DUSP6/DUSP2/LYN/NOD1/SH2B3/SHC2/CD81/TLR6/IL1B	63
BP	GO:0008064	regulation of actin polymerization or depolymerization	39/2112	179/18670	4.041e-05	0.0006406	0.0004628	CORO1A/ADD3/ARPIN/TMOD1/CCR7/COTL1/HCLS1/PFN2/ICAM1/WASL/TMSB10/CCL21/WAS/CDC42EP3/PLEK/NCKAP1L/GMFG/DSTN/VASP/ARPC5L/KANK1/LMOD1/MYO1C/CTTN/FER/CFL1/CAPZA1/VILL/AP1AR/HCK/ARPC1A/WDR1/ABI2/ACTR3/PFN1/IQGAP2/SPTBN1/GSN/ACTR2	39
BP	GO:0010721	negative regulation of cell development	64/2112	344/18670	4.053e-05	0.0006409	0.0004631	GBP1/IGF1/SEMA4A/ASPM/PTHLH/SOX9/SEMA4D/GLI3/SEMA3A/SKI/PPP3CA/SPOCK1/MEIS1/LPAR1/ZNF365/ITGB1BP1/GAK/NPR2/BMPR1A/TRAK2/PMP22/FGF13/IDH2/NLGN1/SOX2/ID3/PTN/PBX1/RYK/PTPRS/SEMA3F/EFNA5/DIXDC1/DAAM2/PLK2/NOTCH1/GDI1/KANK1/MYLIP/PAK1/DPYSL3/EDNRB/GFI1/IL6/ARHGAP4/CD38/ZHX2/BCL11A/SEMA4F/FOXO3/AP1AR/FBLN1/SEMA3E/DDX6/HEY1/DIO3/BAG5/SEMA6B/RNF10/TP53/FEZF2/IL1B/LILRB1/BRINP1	64
BP	GO:0002292	T cell differentiation involved in immune response	20/2112	68/18670	4.086e-05	0.0006445	0.0004657	RELB/SEMA4A/GPR183/CCL19/BATF/IRF4/IL4R/LGALS9/MALT1/RIPK2/CLEC4E/TBX21/CD86/LEF1/IFNG/PTGER4/CD80/IL6/IL18/NLRP3	20
BP	GO:0045429	positive regulation of nitric oxide biosynthetic process	15/2112	43/18670	4.163e-05	0.000655	0.0004732	CLU/HBB/ITGB2/ICAM1/JAK2/CD36/DDAH2/CLEC7A/SMAD3/IFNG/HSP90AB1/PKD2/TLR6/IL1B/PTX3	15
BP	GO:0001771	immunological synapse formation	8/2112	14/18670	4.233e-05	0.0006643	0.00048	PRF1/CCL19/CCR7/CCL21/EPHB1/CD6/DOCK2/CD81	8
BP	GO:0051047	positive regulation of secretion	76/2112	428/18670	4.265e-05	0.0006676	0.0004823	AIM2/CD2/IGF1/RASGRP1/TLR8/HLA-F/MYH10/FCN1/CCL19/SRI/INHBA/OXCT1/ABCG1/TLR2/ITGB2/IL4R/LGALS9/NOD2/ADAM8/WLS/JAK2/IFIH1/ITSN1/HTR2B/TNFRSF14/GATA2/RIPK2/FGR/CRTAM/EGFR/HLA-E/TM7SF3/TAC1/MPC2/CD160/NMB/CLEC4E/AKAP12/TCF7L2/NLGN1/CADM1/DDX58/SNX5/CASP1/RAB27A/PTPN11/RBP4/LEP/IFNG/KMO/OR51E2/PRL/PTGER4/STX4/SYK/EDNRB/STXBP1/HFE/TGFB3/PINK1/TNFRSF4/IL6/PTPN22/CD38/SYBU/FERMT1/CYBA/GAB2/ANG/PANX1/SPTBN1/IL1B/MMP12/CADPS/GPR27/NLRP3	76
BP	GO:0032651	regulation of interleukin-1 beta production	24/2112	90/18670	4.355e-05	0.0006799	0.0004913	AIM2/TNFAIP3/IGF1/TLR8/CCL19/CCR7/LGALS9/NOD2/MALT1/JAK2/RIPK2/SPHK1/CLEC7A/CX3CR1/CASP1/SMAD3/MNDA/IFNG/SERPINB1/HSPB1/NOD1/PANX1/PML/NLRP3	24
BP	GO:0050727	regulation of inflammatory response	84/2112	485/18670	4.366e-05	0.00068	0.0004913	CCL5/SLAMF8/XCL1/PTPRC/TNFAIP3/CCR2/S100A9/IGF1/BIRC3/CLU/NT5E/IDO1/TNFRSF1B/CST7/IL15/MYD88/CCR7/NFE2L1/TLR2/CD200/PTPN2/NOD2/ADAM8/JAK2/CTSC/CFP/GPSM3/EGFR/HLA-E/ADA/PROS1/SPHK1/CLEC7A/TAC1/CR1/SELE/HGF/NFKBIA/SOD1/MAPK13/MCPH1/C5orf30/CCL18/NFKB1/CD6/CD19/SMAD3/GPX4/MFHAS1/BRD4/LEP/IL6ST/AGTR1/IGLC1/IGLV1-44/C7/PTGER4/ADIPOQ/EDNRB/BTK/IL6/IGHG1/NR1H3/FPR2/RB1/IL18/FABP4/CFB/LYN/CEBPA/HCK/CD81/TGM2/SBNO2/PBK/IL2RA/IL1R1/PLA2G7/TLR6/IL1B/CR2/CDH5/C6/NLRP3	84
BP	GO:0046850	regulation of bone remodeling	16/2112	48/18670	4.418e-05	0.0006829	0.0004934	SFRP1/TNFAIP3/TNFRSF11B/CSK/LTBP3/ADAM8/TFRC/EGFR/CA2/LEP/SYK/PDK4/IL6/CD38/INPP5D/S1PR1	16
BP	GO:0032271	regulation of protein polymerization	45/2112	218/18670	4.439e-05	0.0006829	0.0004934	CORO1A/ADD3/ARPIN/TMOD1/TPPP3/CCR7/COTL1/HCLS1/PFN2/ICAM1/WASL/TMSB10/CCL21/WAS/CDC42EP3/TUBB4A/NCKAP1L/GMFG/VASP/ARPC5L/KANK1/LMOD1/MECP2/TERF1/PAK1/MYO1C/CAMSAP2/CTTN/PINK1/MAP1B/FER/CAPZA1/VILL/AP1AR/CLIP3/HCK/ARPC1A/ABI2/ACTR3/PFN1/IQGAP2/SPTBN1/GSN/CDH5/ACTR2	45
BP	GO:0007094	mitotic spindle assembly checkpoint	13/2112	34/18670	4.462e-05	0.0006829	0.0004934	BUB1/NDC80/MAD2L1/PLK1/TPR/ZNF207/BUB1B/CCNB1/CENPF/TTK/AURKB/CDC20/TRIP13	13
BP	GO:0031577	spindle checkpoint	13/2112	34/18670	4.462e-05	0.0006829	0.0004934	BUB1/NDC80/MAD2L1/PLK1/TPR/ZNF207/BUB1B/CCNB1/CENPF/TTK/AURKB/CDC20/TRIP13	13
BP	GO:0043368	positive T cell selection	13/2112	34/18670	4.462e-05	0.0006829	0.0004934	CD3D/CD3E/PTPRC/BCL11B/BATF/IRF4/CD74/PTPN2/CD3G/ZAP70/TBX21/DOCK2/IL6	13
BP	GO:0071173	spindle assembly checkpoint	13/2112	34/18670	4.462e-05	0.0006829	0.0004934	BUB1/NDC80/MAD2L1/PLK1/TPR/ZNF207/BUB1B/CCNB1/CENPF/TTK/AURKB/CDC20/TRIP13	13
BP	GO:0071174	mitotic spindle checkpoint	13/2112	34/18670	4.462e-05	0.0006829	0.0004934	BUB1/NDC80/MAD2L1/PLK1/TPR/ZNF207/BUB1B/CCNB1/CENPF/TTK/AURKB/CDC20/TRIP13	13
BP	GO:0030832	regulation of actin filament length	39/2112	180/18670	4.604e-05	0.0007029	0.0005079	CORO1A/ADD3/ARPIN/TMOD1/CCR7/COTL1/HCLS1/PFN2/ICAM1/WASL/TMSB10/CCL21/WAS/CDC42EP3/PLEK/NCKAP1L/GMFG/DSTN/VASP/ARPC5L/KANK1/LMOD1/MYO1C/CTTN/FER/CFL1/CAPZA1/VILL/AP1AR/HCK/ARPC1A/WDR1/ABI2/ACTR3/PFN1/IQGAP2/SPTBN1/GSN/ACTR2	39
BP	GO:0106106	cold-induced thermogenesis	33/2112	143/18670	4.676e-05	0.0007101	0.0005131	CCR2/HOXC10/CXCR4/IL15/IRF4/IL4R/DIO2/NOVA1/JAK2/CD36/PLAC8/TRPV2/PER2/NOTCH1/ARNTL/LEP/ADIPOQ/SYK/FABP5/G0S2/DDIT3/NR1H3/UCP2/RB1/IL18/FABP4/ABHD6/ACADL/HADH/NPR3/PRKAB1/YBX2/THRA	33
BP	GO:0120161	regulation of cold-induced thermogenesis	33/2112	143/18670	4.676e-05	0.0007101	0.0005131	CCR2/HOXC10/CXCR4/IL15/IRF4/IL4R/DIO2/NOVA1/JAK2/CD36/PLAC8/TRPV2/PER2/NOTCH1/ARNTL/LEP/ADIPOQ/SYK/FABP5/G0S2/DDIT3/NR1H3/UCP2/RB1/IL18/FABP4/ABHD6/ACADL/HADH/NPR3/PRKAB1/YBX2/THRA	33
BP	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	25/2112	96/18670	4.686e-05	0.0007101	0.0005131	PSMB9/TAP1/TAPBP/PSMB8/HLA-F/HLA-A/PSMB10/TAP2/HLA-C/HLA-G/CD36/PSME1/ERAP2/HLA-E/HLA-B/SEC31A/FCGR1B/NCF4/CLEC4A/TAPBPL/IKBKG/HFE/CYBA/NCF1/ITGAV	25
BP	GO:0030183	B cell differentiation	31/2112	131/18670	4.713e-05	0.0007125	0.0005148	SLAMF8/PIK3R1/SFRP1/PTPRC/GPR183/ITGA4/DOCK10/INHBA/PTPN2/TCIRG1/MALT1/HDAC4/ADA/PTPN6/PLCG2/BAK1/CD27/CD40LG/NCKAP1L/MS4A1/CD19/ZFP36L1/FLT3/SYK/BTK/TPD52/INPP5D/ZFP36L2/TP53/IFNA1/CR2	31
BP	GO:0046488	phosphatidylinositol metabolic process	38/2112	174/18670	4.775e-05	0.0007201	0.0005203	PLA2G2D/PLEKHA1/PIK3R1/PIGK/PIP4K2B/HTR2B/SOCS1/CISH/FGF2/SH3YL1/DPM3/PLCG2/PLEK/GPAA1/MTMR14/SOCS2/PLA2G12A/PIK3CD/PIGH/PLEKHA4/PLA2G4C/HTR2A/INPP1/PTPN13/SOCS6/PIK3CA/PIGP/PLEKHA2/PIK3R3/INPP5D/PIP4K2A/FPR2/PIGT/PIGF/MTMR2/MBOAT7/RAB14/BPNT1	38
BP	GO:0051224	negative regulation of protein transport	41/2112	193/18670	4.81e-05	0.0007236	0.0005228	SFRP1/TNFAIP3/GBP1/IL27RA/CSK/TLR8/RHBDF2/PPP3CA/CD200/ANGPT1/ITGB1BP1/CD36/BTN2A2/SRGN/KLF7/IDH2/BARD1/RHBDF1/PTPN11/GDI1/PPM1F/PTGER4/ADIPOQ/SERPINB1/TNFRSF4/PTPN22/ANXA4/NR1H3/UBE2J1/FERMT1/PPP1R11/NDFIP1/HADH/LRRC32/TLR6/IL1B/UBE2G2/PML/RAB11FIP1/LILRB1/NLRP3	41
BP	GO:0051348	negative regulation of transferase activity	55/2112	285/18670	4.951e-05	0.000743	0.0005368	CDKN2C/SFRP1/PTPRC/TNFAIP3/BMP4/UCHL1/LRP6/CDKN1C/CSK/SH3BP5/PPP2CA/DUSP5/PTPN2/ITGB1BP1/RASIP1/MAD2L1/PLK1/SOCS1/DEPTOR/GPRC5A/PTPN6/TAF7/BAG2/RHOH/ZGPAT/LRP5/GMFG/COX11/HEXIM1/IFNG/RGN/ADAR/PPM1F/TERF1/ADIPOQ/MBIP/FBXO5/HSPB1/CEP85/WWTR1/PTPN22/IPO7/DUSP6/DUSP2/TESC/RB1/FABP4/LYN/CEBPA/SH2B3/DVL1/BAG5/TP53/MVP/IL1B	55
BP	GO:0006644	phospholipid metabolic process	76/2112	430/18670	5.005e-05	0.0007492	0.0005413	PLA2G2D/PLEKHA1/CPNE3/PIK3R1/PIGK/CCL19/SERINC3/LPCAT3/CHPT1/CCR7/NOD2/PMVK/PIP4K2B/HTR2B/SOCS1/FGR/CISH/PNPLA6/FGF2/SH3YL1/DPM3/PLCG2/CCL21/PLEK/GPAA1/PLD1/MTMR14/ETNK1/SOCS2/PLA2G12A/PIK3CD/PIGH/PLEKHA4/PLA2G4C/HTR2A/INPP1/CD19/GPX4/PTPN13/LIPG/SOCS6/DGKA/PIK3CA/MECP2/FLT3/PLA1A/SERINC1/PIGP/PRDX6/FABP5/PLEKHA2/CETP/PIK3R3/SGMS1/INPP5D/PTDSS1/PLSCR1/PIP4K2A/FPR2/STARD7/PRKD1/ABHD6/LYN/PIGT/CD81/PIGF/MTMR2/LIPC/MBOAT7/RAB14/PLA2G7/VAV3/BPNT1/ALDH5A1/GPD1L/HADHA	76
BP	GO:0002517	T cell tolerance induction	7/2112	11/18670	5.123e-05	0.0007632	0.0005515	CD3E/IDO1/LILRB2/HLA-G/ICOS/PHLPP1/IL2RA	7
BP	GO:0045060	negative thymic T cell selection	7/2112	11/18670	5.123e-05	0.0007632	0.0005515	CD3E/PTPRC/GLI3/CCR7/CD74/ZAP70/DOCK2	7
BP	GO:0090022	regulation of neutrophil chemotaxis	12/2112	30/18670	5.192e-05	0.0007717	0.0005576	XCL1/RAC2/CCL19/CCR7/JAM3/CD74/DYSF/THBS4/CXCL8/CCL21/CAMK1D/NCKAP1L	12
BP	GO:2000116	regulation of cysteine-type endopeptidase activity	48/2112	239/18670	5.226e-05	0.0007748	0.0005598	LAMP3/AIM2/PSMB9/LCK/S100A9/TNFAIP8/BIRC3/CST7/BID/TNFSF10/LGALS9/MALT1/CRYAB/JAK2/RIPK2/RPS6KA1/DLC1/DAP/CASP10/CLEC7A/BAK1/HGF/SOX2/ASPH/CD27/TP63/NDUFA13/ARL6IP5/CASP1/PMAIP1/LEF1/CYFIP2/SMAD3/FAM162A/VCP/CASP5/MICAL1/PPM1F/SYK/APAF1/NOD1/NLE1/CFLAR/CASP4/GSN/PML/CTSH/NLRP3	48
BP	GO:0008360	regulation of cell shape	34/2112	150/18670	5.329e-05	0.0007883	0.0005696	WASF3/CORO1A/SEMA4A/PLEKHO1/MYH10/SEMA4D/CCL13/ARHGEF18/LPAR1/RHOBTB3/ITGB2/FERMT2/ICAM1/COCH/RHOF/FGR/PDPN/DAG1/DLC1/CDC42EP3/S100A13/RHOH/PTN/PARVA/RHOG/CCL7/RHOD/LST1/SEMA3E/KDR/HCK/WDR1/CCL2/PALMD	34
BP	GO:0033045	regulation of sister chromatid segregation	22/2112	80/18670	5.39e-05	0.0007946	0.0005741	TACC3/PTTG1/PTTG3P/BUB1/NDC80/MAD2L1/PLK1/TPR/DLGAP5/ZNF207/BUB1B/FEN1/ATRX/CCNB1/FBXO5/NIPBL/CENPF/TTK/AURKB/RB1/CDC20/TRIP13	22
BP	GO:0010948	negative regulation of cell cycle process	66/2112	361/18670	5.398e-05	0.0007946	0.0005741	PSMB9/CDKN2C/BMP4/PSMB8/TFDP2/PSMB10/DTL/PTTG1/PTTG3P/BUB1/SKP1/NDC80/KANK2/RRM2/HLA-G/MAD2L1/PLK1/PSME1/CDC14B/BTN2A2/EVI2B/BLM/E2F8/FHL1/TPR/CDK1/ZNF207/EZH2/STAG2/BUB1B/NEK2/TOM1L1/ATRX/PLK2/DONSON/CDC7/ZFP36L1/CCNB1/TERF1/HSP90AB1/DACT1/CCND1/FBXO5/SUZ12/CENPF/APAF1/TTK/MIIP/AURKB/RB1/CDC20/FBXL7/SYF2/PKD2/NAE1/ZFP36L2/PRMT1/SETMAR/PCBP4/CCNF/TRIP13/TP53/CCL2/AURKA/TOPBP1/PML	66
BP	GO:0048247	lymphocyte chemotaxis	19/2112	64/18670	5.483e-05	0.0008043	0.0005811	CCL5/CXCL13/XCL1/CCR2/GPR183/CCL19/CCL13/ADAM8/CXCL10/CCL21/PIK3CD/CCL18/CXCL11/CCL7/SLC12A2/ADAM10/CCL17/CCL2/CCL23	19
BP	GO:0032479	regulation of type I interferon production	30/2112	126/18670	5.489e-05	0.0008043	0.0005811	TRAF3/RELB/TNFAIP3/IRF1/TLR8/STAT1/ZBTB20/MYD88/NFKB2/TLR2/UBE2L6/IRF7/NMI/IFIH1/RIPK2/CREBBP/PLCG2/DDX58/PTPRS/NFKB1/TRIM21/HERC5/PTPN11/SYK/POLR2L/PTPN22/TRIM38/ISG15/MMP12/LILRB1	30
BP	GO:0046677	response to antibiotic	61/2112	327/18670	5.607e-05	0.0008195	0.0005921	PLEKHA1/TNFAIP3/CDO1/PENK/CLU/NQO1/STAT1/OXCT1/AXL/SIGMAR1/HBB/USP46/ICAM1/CRYAB/JAK2/PDGFD/ADA/SPHK1/SLC1A3/CYB5R4/CDK1/BAK1/HGF/VKORC1/EZH2/CD27/ID3/SOD1/MAPK13/PPP2CB/FOXO1/NET1/HYAL1/EFNA5/RBP4/ECT2/LEP/TIMELESS/RPS4X/SLC8A1/ALPL/CCL7/ADIPOQ/CCND1/FOSL1/SPI1/PINK1/IL6/MAOB/TYMS/HP/FOXO3/SDF4/AOC3/CAT/TUFM/ALAD/RPL10A/TP53/GSN/ACTR2	61
BP	GO:0048709	oligodendrocyte differentiation	25/2112	97/18670	5.643e-05	0.0008215	0.0005935	WASF3/CDKN2C/CSK/CLU/TNFRSF1B/CXCR4/PLP1/SOX9/GLI3/NTRK2/LPAR1/ZNF365/TLR2/DAG1/ASPA/ERBB2/FA2H/PTN/DAAM2/CD9/NOTCH1/LYN/TENM4/WDR1/GSN	25
BP	GO:0010463	mesenchymal cell proliferation	15/2112	44/18670	5.66e-05	0.0008215	0.0005935	BMP4/STAT1/SOX9/FGF7/SIX1/BMPR1A/SIX2/SHOX2/NFIB/PTN/LRP5/DCHS1/FGF9/FAT4/LMNA	15
BP	GO:1904407	positive regulation of nitric oxide metabolic process	15/2112	44/18670	5.66e-05	0.0008215	0.0005935	CLU/HBB/ITGB2/ICAM1/JAK2/CD36/DDAH2/CLEC7A/SMAD3/IFNG/HSP90AB1/PKD2/TLR6/IL1B/PTX3	15
BP	GO:0022011	myelination in peripheral nervous system	11/2112	26/18670	5.775e-05	0.0008323	0.0006013	NTRK2/SKI/PARD3/DAG1/FA2H/SOD1/ARHGEF10/ADAM22/MYOC/MPP5/SH3TC2	11
BP	GO:0032292	peripheral nervous system axon ensheathment	11/2112	26/18670	5.775e-05	0.0008323	0.0006013	NTRK2/SKI/PARD3/DAG1/FA2H/SOD1/ARHGEF10/ADAM22/MYOC/MPP5/SH3TC2	11
BP	GO:0071624	positive regulation of granulocyte chemotaxis	11/2112	26/18670	5.775e-05	0.0008323	0.0006013	XCL1/RAC2/CCL19/CCR7/CD74/DYSF/THBS4/CXCL8/CCL21/CAMK1D/NCKAP1L	11
BP	GO:0002704	negative regulation of leukocyte mediated immunity	16/2112	49/18670	5.876e-05	0.0008414	0.0006079	XCL1/PTPRC/CCR2/HLA-F/IL7R/HLA-G/LGALS9/CD96/HLA-E/PTPN6/CR1/TBX21/IL13RA2/HFE/THOC1/LILRB1	16
BP	GO:0032757	positive regulation of interleukin-8 production	16/2112	49/18670	5.876e-05	0.0008414	0.0006079	CD2/TLR8/FCN1/MYD88/TLR2/CD74/LGALS9/NOD2/PRKD2/CLEC7A/TLR5/DDX58/ADIPOQ/SYK/DDIT3/IL1B	16
BP	GO:0007091	metaphase/anaphase transition of mitotic cell cycle	17/2112	54/18670	5.887e-05	0.0008414	0.0006079	TACC3/BUB1/NDC80/MAD2L1/PLK1/TPR/DLGAP5/ZNF207/BUB1B/CCNB1/FBXO5/CENPF/TTK/AURKB/RB1/CDC20/TRIP13	17
BP	GO:0052548	regulation of endopeptidase activity	75/2112	425/18670	5.892e-05	0.0008414	0.0006079	LAMP3/AIM2/PSMB9/SERPINA1/LCK/S100A9/PSMB8/TNFAIP8/BIRC3/TIMP3/SPOCK2/CST7/SERPINA3/SERPINA5/SLPI/PTTG1/SPOCK1/BID/TNFSF10/TIMP4/LGALS9/MALT1/CRYAB/JAK2/TIMP2/PSME1/RIPK2/RPS6KA1/RECK/DLC1/PROS1/DAP/CASP10/CLEC7A/CR1/UBE2Z/SPINT2/ITIH5/BAK1/HGF/SOX2/ASPH/CD27/TP63/NDUFA13/ARL6IP5/PEBP1/CASP1/PMAIP1/LEF1/ADRM1/CYFIP2/SMAD3/FAM162A/VCP/CASP5/SERPINI1/MICAL1/PPM1F/LXN/SYK/SERPINB1/APAF1/APLP2/TFPI/LYN/NOD1/NLE1/CFLAR/SPINK5/CASP4/GSN/PML/CTSH/NLRP3	75
BP	GO:0060390	regulation of SMAD protein signal transduction	10/2112	22/18670	5.998e-05	0.0008545	0.0006174	GDF5/BMP4/CILP/BMPR1A/NUP93/TOB1/PARP1/TGFB3/WWTR1/SPTBN1	10
BP	GO:0007059	chromosome segregation	60/2112	321/18670	6.058e-05	0.000859	0.0006207	TACC3/PTTG1/PTTG3P/MKI67/BUB1/NUSAP1/NCAPD2/NDC80/MAD2L1/SMC6/PLK1/GEM/UBE2B/CDCA8/NCAPH/KIF18B/SRPK1/HJURP/NCAPG/TPR/DLGAP5/ZNF207/STAG2/BUB1B/KIF2C/KIF4A/TOP2A/PRC1/NEK2/FEN1/RMI1/ATRX/RACGAP1/SPC25/ECT2/ZWINT/STAG3/CCNB1/TERF1/FBXO5/BEX4/NIPBL/CEP85/CENPF/REC8/TTK/CHMP2B/AURKB/RB1/CDC20/SLC25A5/TUBG2/SMC4/ACTR3/TRIP13/CCNE2/KIFC1/ACTR2/CHMP1B/KIF23	60
BP	GO:0007568	aging	60/2112	321/18670	6.058e-05	0.000859	0.0006207	PRELP/IGFBP5/CDKN1C/PENK/NQO1/TNFRSF1B/BCL2A1/IL15/KYNU/PPP3CA/NFKB2/ITGB2/HLA-G/ICAM1/BMPR1A/CRYAB/CTSC/SMC6/TIMP2/COMP/ADA/DAG1/DCN/CDK1/BAK1/PCK1/NOX4/TP63/SOD1/HTR2A/GPX4/KL/PLK2/ARNTL/LEP/PAX5/SEC63/KMO/RGN/SLC12A2/EDNRB/FBXO5/TGFB3/AKT3/APAF1/INPP5D/TYMS/FOXO3/LMNA/AURKB/RWDD1/IGFBP2/HMGA1/CAT/ERCC1/PTH1R/TP53/GSN/KRT33B/PML	60
BP	GO:0033044	regulation of chromosome organization	63/2112	342/18670	6.282e-05	0.0008885	0.0006419	NAP1L2/TACC3/PRKCQ/PTTG1/SKI/PTTG3P/MKI67/BUB1/AUTS2/NDC80/MAD2L1/PLK1/PRKD2/GATA2/UBE2B/CDC45/KMT2A/TAF7/TPR/DLGAP5/ZNF207/BUB1B/NEK7/MCPH1/TOP2A/NEK2/RPS6KA4/FEN1/DNMT1/ATRX/BRD4/PAX5/MCM2/CCNB1/EID1/MECP2/MTF2/MPHOSPH8/TERF1/GFI1/FBXO5/PARP1/SPI1/NIPBL/PAF1/PINK1/CENPF/TTK/JARID2/LMNA/AURKB/RB1/CDC20/PRKD1/HMGA1/ERCC1/SETMAR/TRIP13/TP53/USP7/IL1B/PARN/PML	63
BP	GO:0032612	interleukin-1 production	28/2112	115/18670	6.294e-05	0.0008885	0.0006419	AIM2/TNFAIP3/IGF1/TLR8/CCL19/CCR7/LGALS9/NOD2/MALT1/JAK2/CD36/RIPK2/SPHK1/CLEC7A/S100A13/CX3CR1/CASP1/SMAD3/MNDA/IFNG/SERPINB1/HSPB1/NOD1/PANX1/TLR6/IL1B/PML/NLRP3	28
BP	GO:0050715	positive regulation of cytokine secretion	32/2112	139/18670	6.354e-05	0.0008949	0.0006466	AIM2/CD2/RASGRP1/TLR8/FCN1/CCL19/TLR2/IL4R/LGALS9/NOD2/IFIH1/HTR2B/TNFRSF14/RIPK2/FGR/CRTAM/CD160/CLEC4E/AKAP12/CADM1/DDX58/CASP1/IFNG/PTGER4/SYK/PTPN22/FERMT1/PANX1/SPTBN1/IL1B/MMP12/NLRP3	32
BP	GO:1904894	positive regulation of STAT cascade	24/2112	92/18670	6.396e-05	0.0008988	0.0006494	CCL5/CRLF1/IGF1/IL15/IL7R/HCLS1/CRLF3/JAK2/CD40/SOCS1/AKR1B1/GHR/NOTCH1/LEP/IL6ST/IFNG/PECAM1/PRL/FLT3/IL10RA/CTF1/IL6/IL18/LYN	24
BP	GO:0051961	negative regulation of nervous system development	59/2112	315/18670	6.543e-05	0.0009173	0.0006628	SEMA4A/ASPM/SOX9/SEMA4D/GLI3/SEMA3A/SKI/PPP3CA/SPOCK1/MEIS1/LPAR1/ZNF365/TLR2/GAK/BMPR1A/CTSC/TRAK2/PMP22/FGF13/IDH2/NLGN1/SOX2/ID3/PTN/PBX1/RYK/PTPRS/SEMA3F/DIXDC1/DAAM2/PLK2/NOTCH1/GDI1/KANK1/MYLIP/DPYSL3/EDNRB/GFI1/TULP3/IL6/ARHGAP4/CD38/ZHX2/BCL11A/SEMA4F/FOXO3/SEMA3E/DDX6/HEY1/DIO3/BAG5/SEMA6B/RNF10/MTMR2/TP53/RFX4/FEZF2/IL1B/BRINP1	59
BP	GO:0014855	striated muscle cell proliferation	22/2112	81/18670	6.618e-05	0.0009258	0.0006689	PIM1/FOXC1/MEIS1/ANGPT1/ZFPM2/SIX1/BMPR1A/JAK2/YAP1/FGF2/TGFBR3/CDK1/KCNK2/EPHB1/RBP4/NOTCH1/CCNB1/HEY2/FGF9/JARID2/TENM4/CFLAR	22
BP	GO:0002548	monocyte chemotaxis	19/2112	65/18670	6.934e-05	0.0009677	0.0006992	CCL5/SLAMF8/XCL1/CCR2/CCL19/CCL13/CXCL10/CCL21/CCR1/CCL18/NBL1/CCL7/IL6/FPR2/LYN/CCL17/CCL2/CCL23/PLA2G7	19
BP	GO:0002369	T cell cytokine production	14/2112	40/18670	7.168e-05	0.000996	0.0007196	XCL1/CCR2/HLA-F/TNFRSF1B/SASH3/MALT1/TBX21/HFE/IL6/IL18/CD81/IL1R1/IL1B/NLRP3	14
BP	GO:0045124	regulation of bone resorption	14/2112	40/18670	7.168e-05	0.000996	0.0007196	TNFAIP3/TNFRSF11B/CSK/LTBP3/ADAM8/TFRC/EGFR/CA2/SYK/PDK4/IL6/CD38/INPP5D/S1PR1	14
BP	GO:0051781	positive regulation of cell division	23/2112	87/18670	7.214e-05	0.001	0.0007226	BTC/FGF7/ITGB1BP1/PDGFD/HTR2B/CDC14B/FGF2/THBS4/CDC25B/KIF3B/PTN/CSPP1/RACGAP1/ECT2/SSTR5/FGF9/TGFB3/AURKB/VEGFB/KIF20B/CAT/IL1B/KIF23	23
BP	GO:0060759	regulation of response to cytokine stimulus	40/2112	190/18670	7.295e-05	0.001009	0.0007291	CCL5/PTPRC/TNFAIP3/BIRC3/STAT1/TRAF1/CXCR4/VRK2/TLR2/ANGPT1/CD74/AXL/PTPN2/IRF7/JAK2/IFIH1/SOCS1/RIPK2/PTPN6/SPHK1/TXK/DDX58/CASP1/PTPN11/IFNG/ADAR/HSP90AB1/ADIPOQ/SYK/GFI1/IKBKG/IL6/NR1H3/LIFR/IL1RN/CLIP3/SH2B3/CASP4/IL1R1/MMP12	40
BP	GO:0043901	negative regulation of multi-organism process	37/2112	171/18670	7.336e-05	0.001012	0.0007315	CCL5/TNFAIP3/IGF1/ARHGDIB/STAT1/FCN1/SLPI/APOBEC3G/NPR2/HTRA1/OAS1/MICB/ADA/TSPAN6/ISG20/SRPK1/OASL/FAM111A/HPGDS/TRIM21/MPHOSPH8/KRT6A/OAS3/TRIM38/IFIT5/PLSCR1/TRIM26/OVGP1/MX1/ZC3HAV1/SPINK5/IL2RA/ITGAV/ISG15/GSN/PTX3/PML	37
BP	GO:0001655	urogenital system development	61/2112	330/18670	7.359e-05	0.001013	0.0007322	SFRP1/CRLF1/BMP4/CDKN1C/DLG5/PLCE1/STAT1/SOX9/ZBTB16/GLI3/FOXC1/ANGPT1/AR/SULF1/KANK2/SGPL1/SIX1/NUP93/PDGFD/SIX2/YAP1/GATA2/AKR1B1/FGF2/DCN/CEP55/MAGI2/ACAT1/ID3/TP63/NUP160/PBX1/DCHS1/SMAD3/CA2/RBP4/NOTCH1/AGTR1/RGN/PECAM1/TFAP2A/ADIPOQ/NIPBL/WWTR1/CENPF/APAF1/FAT4/EMX2/FSTL3/PKD2/NLE1/CFLAR/REN/CAT/ARL3/POU3F3/HOXA11/GPR4/EAF2/CTSH/AHI1	61
BP	GO:1903409	reactive oxygen species biosynthetic process	29/2112	122/18670	7.483e-05	0.001027	0.0007421	CLU/GCH1/NQO1/HBB/ITGB2/ICAM1/JAK2/CD36/HDAC4/SLC18A2/DDAH2/CLEC7A/CX3CR1/NOX4/SOD1/SMAD3/RAB27A/IFNG/RGN/HSP90AB1/MAOB/GLA/FOXO3/CYBA/PKD2/CFLAR/TLR6/IL1B/PTX3	29
BP	GO:0032606	type I interferon production	30/2112	128/18670	7.492e-05	0.001027	0.0007421	TRAF3/RELB/TNFAIP3/IRF1/TLR8/STAT1/ZBTB20/MYD88/NFKB2/TLR2/UBE2L6/IRF7/NMI/IFIH1/RIPK2/CREBBP/PLCG2/DDX58/PTPRS/NFKB1/TRIM21/HERC5/PTPN11/SYK/POLR2L/PTPN22/TRIM38/ISG15/MMP12/LILRB1	30
BP	GO:0046486	glycerolipid metabolic process	73/2112	414/18670	7.544e-05	0.001032	0.0007456	PLA2G2D/PLEKHA1/CPNE3/PIK3R1/PIGK/GK/PLCE1/SERINC3/LPCAT3/CHPT1/PIP4K2B/HTR2B/SOCS1/CISH/PNPLA6/FGF2/SH3YL1/DPM3/PLCG2/PLEK/SIK1/GPAA1/PLD1/MTMR14/ETNK1/SOCS2/PCK1/PLA2G12A/PIK3CD/PIGH/PLEKHA4/PLA2G4C/HTR2A/INPP1/PTPN11/PTPN13/LIPG/RGN/SOCS6/DGKA/PIK3CA/MECP2/PLA1A/SERINC1/PIGP/PRDX6/FABP5/PLEKHA2/CETP/PIK3R3/INPP5D/PTDSS1/PLSCR1/NR1H3/PIP4K2A/FPR2/FABP4/STARD7/ABHD6/ANG/SLC27A5/PIGT/CAT/PIGF/MTMR2/LIPC/MBOAT7/RAB14/PLA2G7/BPNT1/ALDH5A1/GPD1L/HADHA	73
BP	GO:0002888	positive regulation of myeloid leukocyte mediated immunity	12/2112	31/18670	7.603e-05	0.001034	0.0007474	ITGB2/IL4R/GATA2/FGR/HLA-E/DDX58/DDX1/STX4/SYK/STXBP1/BTK/GAB2	12
BP	GO:0043304	regulation of mast cell degranulation	12/2112	31/18670	7.603e-05	0.001034	0.0007474	RAC2/IL4R/LGALS9/GATA2/FGR/IL13RA2/STXBP2/SYK/STXBP1/FER/GAB2/LYN	12
BP	GO:0071695	anatomical structure maturation	36/2112	165/18670	7.613e-05	0.001034	0.0007474	CDKN1C/IGF1/SEMA4D/NPR2/RECK/DAG1/CDC25B/CX3CR1/SCARF1/DAZL/DCHS1/IRX5/MYOC/LEP/CCNB1/MECP2/EDNRB/FBXO5/TRIM58/REC8/FAT4/TYMS/BCL11A/DDIT3/FOXO3/RB1/FERMT1/MBTPS2/ANG/SPINK5/S1PR1/TRIP13/AURKA/PTBP3/CDH5/HOXA5	36
BP	GO:0070741	response to interleukin-6	16/2112	50/18670	7.741e-05	0.00105	0.0007583	PID1/STAT1/PTPN2/ICAM1/JAK2/PCK1/NFKB1/PTPN11/IL6ST/GFI1/SPI1/IL6/FER/SELPLG/CEBPA/SBNO2	16
BP	GO:0007163	establishment or maintenance of cell polarity	43/2112	210/18670	7.885e-05	0.001067	0.0007708	DLG5/CCL19/CYTH1/PARD3/CCR7/JAM3/RHOBTB3/MAP4/CD3G/NDC80/MAD2L1/PLK1/RHOF/AMOTL2/FGF13/CCL21/SPINT2/RHOH/EPHB1/KIF2C/NCKAP1L/CAP2/PARVA/MCPH1/DOCK2/FEZ1/KANK1/RHOG/HSP90AB1/PAK1/RHOD/MAP1B/CFL1/LMNA/FERMT1/MPP5/KIF20B/WDR1/ACTR3/RAB11FIP2/GSN/CDH5/ACTR2	43
BP	GO:0032637	interleukin-8 production	22/2112	82/18670	8.09e-05	0.001091	0.0007883	PTPRC/CD2/TLR8/FCN1/MYD88/TLR2/CD74/LGALS9/NOD2/PRKD2/CLEC7A/TLR5/DDX58/LEP/ADIPOQ/SYK/PTPN22/ANXA4/DDIT3/NOD1/TLR6/IL1B	22
BP	GO:0030168	platelet activation	34/2112	153/18670	8.112e-05	0.001091	0.0007883	LCK/PIK3R1/PRKCH/PRKCQ/PRKCB/AXL/LCP2/HBB/CD40/COMP/PDPN/PTPN6/PLCG2/PLEK/CD40LG/PTPN11/VAV1/CD9/DGKA/PIK3CA/SYK/TEC/STXBP1/HSPB1/IL6/FZD6/PRKG1/PLSCR1/MYL9/LYN/SH2B3/MERTK/GP1BA/VAV3	34
BP	GO:0051056	regulation of small GTPase mediated signal transduction	62/2112	338/18670	8.117e-05	0.001091	0.0007883	KITLG/IGF1/RASGRP1/RAC2/PLCE1/ARHGDIB/FAM13A/ARHGAP25/SIPA1/CYTH1/SH2B2/CDON/ARHGEF18/LPAR1/AUTS2/MAPRE2/RASIP1/KANK2/ARHGEF9/JAK2/ARHGEF26/ITSN1/RHOF/TIMP2/DLC1/STARD8/GPR18/DENND1A/ARHGAP17/RHOH/ARHGAP22/ARHGEF3/ARHGEF10/PPP2CB/GMIP/ARHGEF12/NET1/PSD3/VAV1/TNFAIP1/GPR65/RASA2/CHN1/RACGAP1/NOTCH1/MYOC/ECT2/GDI1/KANK1/RHOG/CYTH4/PSD4/RHOD/AKAP13/ARHGAP4/RALBP1/DENND4B/LYN/GPR4/VAV3/ARHGAP12/SCAI	62
BP	GO:0034134	toll-like receptor 2 signaling pathway	8/2112	15/18670	8.17e-05	0.001091	0.0007883	TNFAIP3/TLR2/TNIP2/RIPK2/MFHAS1/CYBA/LYN/TLR6	8
BP	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	8/2112	15/18670	8.17e-05	0.001091	0.0007883	STAT1/TLR2/NOD2/JAK2/AKAP12/IFNG/KDR/CCL2	8
BP	GO:2001185	regulation of CD8-positive, alpha-beta T cell activation	8/2112	15/18670	8.17e-05	0.001091	0.0007883	XCL1/IRF1/RUNX3/SOCS1/HLA-E/NCKAP1L/HFE/LILRB1	8
BP	GO:0050853	B cell receptor signaling pathway	30/2112	129/18670	8.721e-05	0.001154	0.0008341	ITK/PLEKHA1/TRBC1/LCK/PTPRC/CTLA4/LPXN/PRKCH/RFTN1/PRKCB/PTPN6/IGHM/IGLL5/PLCG2/NCKAP1L/PIK3CD/MS4A1/CD19/PAX5/MNDA/IGLC1/SYK/TEC/BTK/PTPN22/CD38/IGHG1/LYN/CD81/VAV3	30
BP	GO:1904035	regulation of epithelial cell apoptotic process	23/2112	88/18670	8.734e-05	0.001154	0.0008341	NDNF/TNFAIP3/ITGA4/AKR1C3/ANGPT1/HLA-G/ICAM1/TNIP2/JAK2/CD40/SCG2/GATA2/CD160/TCF7L2/CD40LG/ANGPTL4/ZFP36L1/IL6/FOXO3/KDR/CFLAR/CCL2/GSN	23
BP	GO:0002062	chondrocyte differentiation	29/2112	123/18670	8.749e-05	0.001154	0.0008341	GDF5/BMP4/RUNX3/SCARA3/WNT5B/TRPS1/PTHLH/FGF18/SOX9/ZBTB16/GLI3/LTBP3/SOX5/SULF1/COCH/BMPR1A/SIX2/COMP/SHOX2/NFIB/COL14A1/CREB3L2/GLG1/CHST11/EFEMP1/SMAD3/FGF9/PTH1R/HOXA11	29
BP	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	11/2112	27/18670	8.752e-05	0.001154	0.0008341	DTL/CDC25B/SMARCD3/CDK1/PBX1/BRD4/CDC7/CCNB1/MECP2/CCND1/FBXO5	11
BP	GO:0036336	dendritic cell migration	11/2112	27/18670	8.752e-05	0.001154	0.0008341	CCL5/SLAMF8/CCR5/CCR2/CXCR4/GPR183/CCL19/CCR7/LGALS9/CCL21/CCR1	11
BP	GO:0097191	extrinsic apoptotic signaling pathway	45/2112	224/18670	8.757e-05	0.001154	0.0008341	KITLG/PIK3R1/SFRP1/PTPRC/TNFAIP3/BMP4/IGF1/TIMP3/TNFRSF1B/EYA4/BCL2A1/TRAF1/INHBA/BID/TNFSF10/AR/EYA2/ICAM1/JAK2/SCG2/YAP1/DEPTOR/IFI27/BAK1/HGF/TCF7L2/CD27/NDUFA13/BCL2L2/PMAIP1/SMAD3/ZMYND11/IFNG/PPP1CA/STX4/ACVR1/CTTN/G0S2/FOXO3/LMNA/CFLAR/ITGAV/MOAP1/IL1B/PML	45
BP	GO:0010742	macrophage derived foam cell differentiation	13/2112	36/18670	8.94e-05	0.001171	0.0008461	PRKCH/STAT1/ABCG1/CD36/NFKBIA/NFKB1/AGTR1/ADIPOQ/CETP/NR1H3/IL18/ITGAV/SOAT2	13
BP	GO:0090077	foam cell differentiation	13/2112	36/18670	8.94e-05	0.001171	0.0008461	PRKCH/STAT1/ABCG1/CD36/NFKBIA/NFKB1/AGTR1/ADIPOQ/CETP/NR1H3/IL18/ITGAV/SOAT2	13
BP	GO:0090218	positive regulation of lipid kinase activity	13/2112	36/18670	8.94e-05	0.001171	0.0008461	CCL19/CCR7/NOD2/FGR/FGF2/CCL21/CD19/FLT3/FPR2/PRKD1/LYN/CD81/VAV3	13
BP	GO:0030203	glycosaminoglycan metabolic process	35/2112	160/18670	8.999e-05	0.001176	0.0008499	PRELP/NDNF/FMOD/GPC5/SPOCK2/IL15/OGN/PIM1/FOXC1/CHST15/ANGPT1/HMMR/EXTL2/FGF2/CHST3/LYVE1/DCN/BGN/CSPG4/ITIH5/HGF/CHST11/LUM/NFKB1/VCAN/HYAL1/UGDH/IDUA/FUCA1/GPC4/EXT2/B3GNT2/STAB2/IL1B/B4GALT2	35
BP	GO:0044272	sulfur compound biosynthetic process	40/2112	192/18670	9.288e-05	0.001209	0.0008735	PRELP/BHMT2/FMOD/CDO1/OGN/GSTM5/CHST15/ANGPT1/GSTM3/GSTA4/CBS/SLC26A2/ESD/CHST3/CNDP2/DCN/BGN/MPC2/CSPG4/SP1/ACAT1/CHST11/LUM/HPGDS/ACACB/VCAN/HSD17B12/MAT1A/UGDH/PDK4/B3GNT2/ELOVL4/MPC1/HAGH/ELOVL2/GSTO1/GSTM2/ACSL5/ELOVL5/B4GALT2	40
BP	GO:1901136	carbohydrate derivative catabolic process	40/2112	192/18670	9.288e-05	0.001209	0.0008735	PRELP/AMPD3/TYMP/FMOD/GPC5/NT5E/GALT/OGN/UPP1/HMMR/APOBEC3G/APOBEC3B/ADA/FGF2/LYVE1/DCN/PDE1A/BGN/CSPG4/ACAT1/LUM/VCAN/HYAL1/EDEM1/IDUA/NAGK/NUDT11/FUCA1/PNP/GPC4/AOAH/GLA/ENTPD4/OVGP1/EDEM2/MANBA/HINT1/STAB2/MMP12/GPD1L	40
BP	GO:0030888	regulation of B cell proliferation	18/2112	61/18670	9.326e-05	0.001211	0.0008753	PTPRC/CTLA4/GPR183/SASH3/CD74/CD40/TFRC/ADA/NCKAP1L/MNDA/BTK/TNFRSF4/CD38/INPP5D/CD320/LYN/CD81/VAV3	18
BP	GO:0001822	kidney development	53/2112	278/18670	9.363e-05	0.001214	0.0008769	SFRP1/CRLF1/BMP4/CDKN1C/DLG5/PLCE1/STAT1/SOX9/ZBTB16/GLI3/FOXC1/ANGPT1/SULF1/KANK2/SGPL1/SIX1/PDGFD/SIX2/YAP1/AKR1B1/FGF2/DCN/MAGI2/ACAT1/ID3/NUP160/PBX1/DCHS1/SMAD3/CA2/NOTCH1/AGTR1/RGN/PECAM1/TFAP2A/ADIPOQ/NIPBL/WWTR1/CENPF/APAF1/FAT4/FSTL3/PKD2/NLE1/CFLAR/REN/CAT/ARL3/POU3F3/HOXA11/GPR4/CTSH/AHI1	53
BP	GO:0002726	positive regulation of T cell cytokine production	9/2112	19/18670	9.528e-05	0.001229	0.0008877	XCL1/SASH3/MALT1/IL6/IL18/CD81/IL1R1/IL1B/NLRP3	9
BP	GO:0032753	positive regulation of interleukin-4 production	10/2112	23/18670	9.538e-05	0.001229	0.0008877	CD3E/PRKCQ/SASH3/IRF4/LGALS9/HLA-E/CD40LG/CD86/SYK/NLRP3	10
BP	GO:0036037	CD8-positive, alpha-beta T cell activation	10/2112	23/18670	9.538e-05	0.001229	0.0008877	XCL1/IRF1/RUNX3/SOCS1/HLA-E/GPR18/NCKAP1L/CLEC4A/HFE/LILRB1	10
BP	GO:0045787	positive regulation of cell cycle	69/2112	389/18670	9.74e-05	0.001252	0.0009046	LRP6/TFDP2/IGF1/BTC/DTL/CCND2/NUSAP1/UBE2C/NDC80/CRLF3/MAD2L1/MEIS2/EGFR/CDC14B/UBE2B/CDC45/EVI2B/E2F8/SPHK1/CDC25B/KIF3B/TPR/CCNT1/SMARCD3/CDK1/DLGAP5/EZH2/LRP5/CCPG1/PBX1/DAZL/FEN1/CSPP1/TRIM21/HYAL1/PTPN11/ATRX/PLK2/CKS2/RACGAP1/BRD4/ECT2/CDC7/SSTR5/CCNB1/MECP2/HSP90AB1/CCND1/DBF4/FBXO5/FOSL1/CKS1B/NIPBL/PAF1/AURKB/RB1/CUL4B/PKD2/KIF20B/THOC1/PRMT1/SETMAR/PCBP4/TP53/GDPD5/AURKA/IL1B/PML/KIF23	69
BP	GO:0001912	positive regulation of leukocyte mediated cytotoxicity	17/2112	56/18670	9.813e-05	0.001256	0.0009076	XCL1/PTPRC/RASGRP1/HLA-F/HLA-A/HLA-C/HLA-G/MICB/CRTAM/HLA-E/SH2D1A/CD160/HLA-B/CD226/CADM1/VAV1/FAM49B	17
BP	GO:0044784	metaphase/anaphase transition of cell cycle	17/2112	56/18670	9.813e-05	0.001256	0.0009076	TACC3/BUB1/NDC80/MAD2L1/PLK1/TPR/DLGAP5/ZNF207/BUB1B/CCNB1/FBXO5/CENPF/TTK/AURKB/RB1/CDC20/TRIP13	17
BP	GO:0019932	second-messenger-mediated signaling	76/2112	439/18670	0.0001004	0.001282	0.0009263	CXCL9/CCR5/NDNF/CD3E/PTPRC/CCR2/GBP1/IGF1/GNAL/PLCE1/PTHLH/CXCR4/SOX9/SRI/TRAT1/LAT/PPP2CA/ANK2/MCTP1/PPP3CA/CCR7/LPAR1/NPR2/ACKR3/CD36/HDAC4/HTR2B/CXCL10/NDUFS4/EGFR/UBE2B/DDAH2/ADA/SPHK1/ZAP70/CXCL8/SELE/PLCG2/TMEM100/PLEK/CCR1/CX3CR1/PLN/CXCR6/SGCD/ATP1B1/HRH1/GPR65/FPR1/AGTR1/RGN/ATP1A2/CXCL11/OR51E2/PTGFR/SLC8A1/PTGER4/SYK/P2RY6/APLNR/EDNRB/BTK/AKAP13/PRKG1/CCR8/FPR2/PDE3B/KDR/PKD2/GSTO1/GSTM2/PTH1R/CAMTA1/HINT1/S1PR4/CCRL2	76
BP	GO:0001954	positive regulation of cell-matrix adhesion	16/2112	51/18670	0.000101	0.001282	0.0009263	CD3E/SFRP1/CCR7/EMP2/ITGB1BP1/CD36/DAG1/CCL21/SKAP1/SMAD3/MYOC/PPM1F/PLEKHA2/FERMT1/KDR/COL16A1	16
BP	GO:0030071	regulation of mitotic metaphase/anaphase transition	16/2112	51/18670	0.000101	0.001282	0.0009263	BUB1/NDC80/MAD2L1/PLK1/TPR/DLGAP5/ZNF207/BUB1B/CCNB1/FBXO5/CENPF/TTK/AURKB/RB1/CDC20/TRIP13	16
BP	GO:0002715	regulation of natural killer cell mediated immunity	15/2112	46/18670	0.0001012	0.001282	0.0009263	RASGRP1/HLA-F/HLA-G/LGALS9/CD96/MICB/CRTAM/HLA-E/SH2D1A/CD160/CD226/CADM1/VAV1/LEP/LILRB1	15
BP	GO:0071354	cellular response to interleukin-6	15/2112	46/18670	0.0001012	0.001282	0.0009263	PID1/STAT1/PTPN2/ICAM1/JAK2/NFKB1/PTPN11/IL6ST/GFI1/SPI1/IL6/FER/SELPLG/CEBPA/SBNO2	15
BP	GO:0032635	interleukin-6 production	35/2112	161/18670	0.0001027	0.001298	0.0009381	TNFAIP3/IL27RA/SLAMF1/CSK/TLR8/LILRB2/ZBTB20/MYD88/TLR2/CD200/CD74/LGALS9/NOD2/CD36/IFIH1/RIPK2/PTPN6/CLEC7A/HGF/NCKAP1L/MAPK13/DDX58/PTPN11/LEP/SYK/MAPKAPK2/IL6/PTPN22/INPP5D/CYBA/IL18/IL1RN/NOD1/TLR6/IL1B	35
BP	GO:0050679	positive regulation of epithelial cell proliferation	42/2112	206/18670	0.000105	0.001325	0.0009571	CCL5/SFRP1/TNFAIP3/BMP4/IGF1/SOX9/ITGA4/FGF7/HTRA1/AR/NOD2/BMPR1A/DYSF/PRKD2/HTR2B/SCG2/GATA2/EGFR/FGF2/THBS4/ERBB2/SP1/TCF7L2/PPP1R16B/PTN/TP63/HYAL1/FZD7/NOTCH1/AGTR1/ARNT/CCND1/APLNR/FGF9/AKT3/CYBA/VEGFB/PRKD1/ANG/KDR/CFLAR/MMP12	42
BP	GO:0046427	positive regulation of JAK-STAT cascade	23/2112	89/18670	0.0001053	0.001326	0.0009583	CCL5/CRLF1/IGF1/IL15/HCLS1/CRLF3/JAK2/CD40/SOCS1/AKR1B1/GHR/NOTCH1/LEP/IL6ST/IFNG/PECAM1/PRL/FLT3/IL10RA/CTF1/IL6/IL18/LYN	23
BP	GO:1903707	negative regulation of hemopoiesis	34/2112	155/18670	0.0001064	0.001337	0.0009658	PIK3R1/SFRP1/CTLA4/BMP4/IRF1/RUNX3/ZBTB16/GLI3/INHBA/MEIS1/CD74/PTPN2/IL4R/HLA-G/LILRB3/SOCS1/GATA2/MEIS2/GPR171/ERBB2/TBX21/LILRB4/NFKBIA/NOTCH1/ZFP36L1/ADIPOQ/PAF1/INPP5D/LYN/FSTL3/PRMT1/TOB2/HOXA5/LILRB1	34
BP	GO:0033006	regulation of mast cell activation involved in immune response	12/2112	32/18670	0.0001092	0.001367	0.0009874	RAC2/IL4R/LGALS9/GATA2/FGR/IL13RA2/STXBP2/SYK/STXBP1/FER/GAB2/LYN	12
BP	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	12/2112	32/18670	0.0001092	0.001367	0.0009874	CCL19/CCR7/NOD2/FGR/FGF2/CCL21/CD19/FLT3/FPR2/PRKD1/LYN/VAV3	12
BP	GO:2001056	positive regulation of cysteine-type endopeptidase activity	33/2112	149/18670	0.0001098	0.001371	0.0009906	AIM2/LCK/S100A9/BID/TNFSF10/LGALS9/MALT1/JAK2/RIPK2/DLC1/DAP/CASP10/CLEC7A/BAK1/ASPH/NDUFA13/ARL6IP5/CASP1/PMAIP1/CYFIP2/SMAD3/FAM162A/VCP/CASP5/PPM1F/SYK/APAF1/NOD1/CASP4/GSN/PML/CTSH/NLRP3	33
BP	GO:0042116	macrophage activation	24/2112	95/18670	0.0001107	0.001374	0.0009928	PTPRC/CLU/TLR8/CST7/TLR2/CD200/CD74/ITGB2/IL4R/DYSF/TNIP2/JAK2/CTSC/SPHK1/CD93/MFHAS1/IFNG/SYK/IL6/NR1H3/FPR2/CEBPA/SBNO2/TLR6	24
BP	GO:0110020	regulation of actomyosin structure organization	24/2112	95/18670	0.0001107	0.001374	0.0009928	PIK3R1/SFRP1/LIMCH1/LPAR1/PFN2/ITGB1BP1/DLC1/TAC1/WAS/NOX4/ARHGEF10/SMAD3/CORO2B/GPR65/MYOC/ECT2/PPM1F/PTGER4/PAK1/TGFB3/AKAP13/WASF2/S1PR1/PFN1	24
BP	GO:0002468	dendritic cell antigen processing and presentation	7/2112	12/18670	0.0001109	0.001374	0.0009928	CCL19/CCR7/CD74/NOD2/CCL21/CLEC4A/NOD1	7
BP	GO:0043383	negative T cell selection	7/2112	12/18670	0.0001109	0.001374	0.0009928	CD3E/PTPRC/GLI3/CCR7/CD74/ZAP70/DOCK2	7
BP	GO:0045862	positive regulation of proteolysis	65/2112	363/18670	0.0001154	0.001427	0.001031	AIM2/LCK/S100A9/CLU/TNFRSF1B/PCOLCE2/ANTXR1/BID/TNFSF10/CBFA2T3/LGALS9/MALT1/ADAM8/JAK2/CTSC/PLK1/PSME1/RIPK2/DLC1/CHFR/DAP/CASP10/SPON1/CLEC7A/CR1/BAG2/BAK1/ASPH/NDUFA13/ARL6IP5/PCOLCE/CASP1/PMAIP1/ADRM1/CYFIP2/SMAD3/EDEM1/PLK2/FAM162A/VCP/CASP5/IFNG/RGN/PPM1F/SYK/PINK1/APAF1/RCN3/RNF19B/FBLN1/LYN/NOD1/CEBPA/DVL1/EDEM2/CFLAR/CASP4/AURKA/RNF14/GSN/IL1B/PML/C6/CTSH/NLRP3	65
BP	GO:0030833	regulation of actin filament polymerization	35/2112	162/18670	0.000117	0.001444	0.001043	CORO1A/ADD3/ARPIN/TMOD1/CCR7/COTL1/HCLS1/PFN2/ICAM1/WASL/TMSB10/CCL21/WAS/CDC42EP3/NCKAP1L/GMFG/VASP/ARPC5L/KANK1/LMOD1/MYO1C/CTTN/FER/CAPZA1/VILL/AP1AR/HCK/ARPC1A/ABI2/ACTR3/PFN1/IQGAP2/SPTBN1/GSN/ACTR2	35
BP	GO:0051492	regulation of stress fiber assembly	22/2112	84/18670	0.0001193	0.00147	0.001062	PIK3R1/SFRP1/LIMCH1/LPAR1/PFN2/ITGB1BP1/DLC1/TAC1/WAS/NOX4/ARHGEF10/SMAD3/CORO2B/GPR65/MYOC/PPM1F/PTGER4/PAK1/TGFB3/WASF2/S1PR1/PFN1	22
BP	GO:2001233	regulation of apoptotic signaling pathway	71/2112	406/18670	0.0001221	0.001501	0.001085	LCK/SFRP1/PTPRC/TNFAIP3/S100A9/BMP4/TFDP2/IGF1/TIMP3/CLU/EYA4/BCL2A1/TRAF1/SERINC3/TPD52L1/INHBA/GZMB/CD74/BID/PTPN2/TNFSF10/AR/EYA2/ICAM1/LGALS9/ACKR3/JAK2/CTSC/TMEM14A/SCG2/YAP1/DEPTOR/BAK1/HGF/TCF7L2/CX3CR1/TP63/NDUFA13/SOD1/BCL2L2/PMAIP1/SMAD3/ZMYND11/FAM162A/HIGD1A/PPP1CA/STX4/ACVR1/PARP1/HSPB1/CTTN/PINK1/APAF1/SGMS1/G0S2/IVNS1ABP/DDIT3/LMNA/RB1/SLC25A5/TP53BP2/BAG5/NLE1/CFLAR/ITGAV/TP53/MOAP1/GSN/IL1B/PML/CTSH	71
BP	GO:0014037	Schwann cell differentiation	13/2112	37/18670	0.0001236	0.001517	0.001096	NTRK2/SKI/PARD3/LAMA2/DAG1/CDK1/FA2H/SOD1/ARHGEF10/ADAM22/MYOC/MPP5/SH3TC2	13
BP	GO:0051304	chromosome separation	23/2112	90/18670	0.0001265	0.001549	0.001119	TACC3/PTTG1/PTTG3P/BUB1/NCAPD2/NDC80/MAD2L1/PLK1/NCAPH/TPR/DLGAP5/ZNF207/BUB1B/TOP2A/RMI1/CCNB1/FBXO5/CENPF/TTK/AURKB/RB1/CDC20/TRIP13	23
BP	GO:0010818	T cell chemotaxis	11/2112	28/18670	0.0001295	0.001579	0.001141	CCL5/CXCL13/XCL1/CCR2/GPR183/CXCL10/CCL21/PIK3CD/CXCL11/SLC12A2/ADAM10	11
BP	GO:0045577	regulation of B cell differentiation	11/2112	28/18670	0.0001295	0.001579	0.001141	SLAMF8/SFRP1/INHBA/PTPN6/CD27/NCKAP1L/ZFP36L1/SYK/BTK/INPP5D/ZFP36L2	11
BP	GO:0038093	Fc receptor signaling pathway	47/2112	241/18670	0.0001304	0.001588	0.001147	ITK/PSMB9/PIK3R1/PTPRC/PSMB8/CD247/PRKCQ/PSMB10/LAT/PPP3CA/MS4A2/SKP1/LCP2/CD3G/MALT1/WASL/PSME1/FGR/PLCG2/WAS/CLEC4E/FCGR1B/DOCK1/NCKAP1L/NFKB1/CYFIP2/VAV1/IGLC1/IGLV1-44/PIK3CA/HSP90AB1/PAK1/MYO1C/SYK/TEC/IKBKG/BTK/FER/IGHG1/GAB2/LYN/HCK/ARPC1A/WASF2/ACTR3/VAV3/ACTR2	47
BP	GO:0032330	regulation of chondrocyte differentiation	16/2112	52/18670	0.0001308	0.001588	0.001148	GDF5/BMP4/TRPS1/PTHLH/FGF18/SOX9/ZBTB16/GLI3/LTBP3/SOX5/SIX2/SHOX2/GLG1/EFEMP1/SMAD3/HOXA11	16
BP	GO:0031641	regulation of myelination	14/2112	42/18670	0.0001313	0.001588	0.001148	WASF3/TYMP/TNFRSF1B/CST7/PARD3/CTSC/DAG1/HGF/PTN/ZPR1/ITGAX/TENM4/RNF10/MTMR2	14
BP	GO:0033003	regulation of mast cell activation	14/2112	42/18670	0.0001313	0.001588	0.001148	RAC2/IL4R/LGALS9/GATA2/FGR/CD226/IL13RA2/STXBP2/SYK/STXBP1/FER/PLSCR1/GAB2/LYN	14
BP	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	21/2112	79/18670	0.0001344	0.00162	0.001171	PSMB9/TAP1/TAPBP/PSMB8/HLA-F/HLA-A/PSMB10/TAP2/HLA-C/HLA-G/CD36/PSME1/HLA-E/HLA-B/FCGR1B/NCF4/CLEC4A/IKBKG/CYBA/NCF1/ITGAV	21
BP	GO:0071260	cellular response to mechanical stimulus	21/2112	79/18670	0.0001344	0.00162	0.001171	IRF1/TLR8/SOX9/MYD88/HDAC4/CD40/EGFR/DAG1/BAK1/TLR5/KCNJ2/NFKB1/CASP1/PTPN11/MAP3K2/CASP5/PIEZO2/ATP1A2/PTGER4/CYBA/IL1B	21
BP	GO:0006469	negative regulation of protein kinase activity	46/2112	235/18670	0.0001398	0.001681	0.001215	CDKN2C/SFRP1/PTPRC/TNFAIP3/BMP4/UCHL1/LRP6/CDKN1C/SH3BP5/PPP2CA/DUSP5/PTPN2/ITGB1BP1/RASIP1/PLK1/SOCS1/DEPTOR/GPRC5A/PTPN6/TAF7/ZGPAT/LRP5/GMFG/HEXIM1/IFNG/RGN/ADAR/PPM1F/ADIPOQ/MBIP/HSPB1/CEP85/WWTR1/PTPN22/IPO7/DUSP6/DUSP2/TESC/RB1/FABP4/LYN/CEBPA/SH2B3/DVL1/MVP/IL1B	46
BP	GO:0006022	aminoglycan metabolic process	36/2112	170/18670	0.0001443	0.001733	0.001252	PRELP/NDNF/FMOD/GPC5/SPOCK2/IL15/OGN/PIM1/FOXC1/CHST15/ANGPT1/HMMR/EXTL2/FGF2/CHST3/LYVE1/DCN/BGN/CSPG4/ITIH5/HGF/CHST11/LUM/NFKB1/VCAN/HYAL1/UGDH/IDUA/FUCA1/GPC4/EXT2/B3GNT2/OVGP1/STAB2/IL1B/B4GALT2	36
BP	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway	10/2112	24/18670	0.000147	0.001756	0.001269	LCK/PTPRC/PRKCH/TRAT1/CCR7/PRKCB/PRKD2/ADA/CD226/CD81	10
BP	GO:0071214	cellular response to abiotic stimulus	60/2112	331/18670	0.0001471	0.001756	0.001269	RELB/PIK3R1/SFRP1/IRF1/TLR8/SOX9/SIPA1/MYD88/NUCKS1/MFAP4/CRYAB/DYSF/HDAC4/CD40/YAP1/AKR1B1/EGFR/DAG1/BLM/CREBBP/OPN3/BAK1/ADIRF/PCK1/PTN/TLR5/NOX4/MICU1/MAPK13/KCNJ2/NFKB1/CASP1/NET1/HYAL1/PTPN11/ECT2/MAP3K2/CASP5/PIEZO2/ZFP36L1/ATP1A2/PTGER4/MBIP/PARP1/SLC25A23/LRRC8D/NIPBL/AURKB/CYBA/GUCA1A/METAP2/CUL4B/RAD51AP1/PKD2/MYLK/ERCC1/PBK/TP53/IL1B/GTF2H5	60
BP	GO:0104004	cellular response to environmental stimulus	60/2112	331/18670	0.0001471	0.001756	0.001269	RELB/PIK3R1/SFRP1/IRF1/TLR8/SOX9/SIPA1/MYD88/NUCKS1/MFAP4/CRYAB/DYSF/HDAC4/CD40/YAP1/AKR1B1/EGFR/DAG1/BLM/CREBBP/OPN3/BAK1/ADIRF/PCK1/PTN/TLR5/NOX4/MICU1/MAPK13/KCNJ2/NFKB1/CASP1/NET1/HYAL1/PTPN11/ECT2/MAP3K2/CASP5/PIEZO2/ZFP36L1/ATP1A2/PTGER4/MBIP/PARP1/SLC25A23/LRRC8D/NIPBL/AURKB/CYBA/GUCA1A/METAP2/CUL4B/RAD51AP1/PKD2/MYLK/ERCC1/PBK/TP53/IL1B/GTF2H5	60
BP	GO:0032677	regulation of interleukin-8 production	20/2112	74/18670	0.0001505	0.001793	0.001295	PTPRC/CD2/TLR8/FCN1/MYD88/TLR2/CD74/LGALS9/NOD2/PRKD2/CLEC7A/TLR5/DDX58/ADIPOQ/SYK/PTPN22/ANXA4/DDIT3/TLR6/IL1B	20
BP	GO:0001959	regulation of cytokine-mediated signaling pathway	37/2112	177/18670	0.0001553	0.001839	0.001329	CCL5/PTPRC/TNFAIP3/BIRC3/STAT1/TRAF1/CXCR4/VRK2/ANGPT1/CD74/AXL/PTPN2/IRF7/JAK2/SOCS1/RIPK2/PTPN6/SPHK1/TXK/CASP1/PTPN11/IFNG/ADAR/HSP90AB1/ADIPOQ/SYK/GFI1/IKBKG/IL6/NR1H3/LIFR/IL1RN/CLIP3/SH2B3/CASP4/IL1R1/MMP12	37
BP	GO:0002827	positive regulation of T-helper 1 type immune response	9/2112	20/18670	0.0001559	0.001839	0.001329	XCL1/CCR2/IL27RA/CCL19/RIPK2/CD80/IL18/IL1R1/IL1B	9
BP	GO:0008356	asymmetric cell division	9/2112	20/18670	0.0001559	0.001839	0.001329	ASPM/ZBTB16/PARD3/SOX5/GOLGA2/ETV5/FGF13/ACTR3/ACTR2	9
BP	GO:0033630	positive regulation of cell adhesion mediated by integrin	9/2112	20/18670	0.0001559	0.001839	0.001329	CCL5/CXCL13/CD3E/PTPN6/CCL21/NCKAP1L/SKAP1/SYK/FERMT1	9
BP	GO:0050860	negative regulation of T cell receptor signaling pathway	9/2112	20/18670	0.0001559	0.001839	0.001329	GBP1/PVRIG/PTPN2/BTN2A2/PTPN6/CD160/LILRB4/PTPN22/UBASH3A	9
BP	GO:0042093	T-helper cell differentiation	17/2112	58/18670	0.0001587	0.001869	0.00135	RELB/SEMA4A/GPR183/CCL19/BATF/IRF4/IL4R/MALT1/RIPK2/TBX21/CD86/LEF1/PTGER4/CD80/IL6/IL18/NLRP3	17
BP	GO:0032675	regulation of interleukin-6 production	33/2112	152/18670	0.0001639	0.001927	0.001392	TNFAIP3/IL27RA/SLAMF1/CSK/TLR8/LILRB2/ZBTB20/MYD88/TLR2/CD200/CD74/LGALS9/NOD2/CD36/IFIH1/RIPK2/PTPN6/CLEC7A/HGF/NCKAP1L/MAPK13/DDX58/PTPN11/SYK/MAPKAPK2/IL6/PTPN22/INPP5D/CYBA/IL1RN/NOD1/TLR6/IL1B	33
BP	GO:0006968	cellular defense response	16/2112	53/18670	0.0001678	0.001965	0.00142	ITK/CXCL9/CCR5/CCR2/PRF1/LILRB2/TRAT1/TCIRG1/GNLY/HLA-G/SH2D1A/CX3CR1/ZNF148/MNDA/FOSL1/NCF1	16
BP	GO:1902099	regulation of metaphase/anaphase transition of cell cycle	16/2112	53/18670	0.0001678	0.001965	0.00142	BUB1/NDC80/MAD2L1/PLK1/TPR/DLGAP5/ZNF207/BUB1B/CCNB1/FBXO5/CENPF/TTK/AURKB/RB1/CDC20/TRIP13	16
BP	GO:0033673	negative regulation of kinase activity	49/2112	257/18670	0.0001684	0.001968	0.001422	CDKN2C/SFRP1/PTPRC/TNFAIP3/BMP4/UCHL1/LRP6/CDKN1C/CSK/SH3BP5/PPP2CA/DUSP5/PTPN2/ITGB1BP1/RASIP1/PLK1/SOCS1/DEPTOR/GPRC5A/PTPN6/TAF7/RHOH/ZGPAT/LRP5/GMFG/COX11/HEXIM1/IFNG/RGN/ADAR/PPM1F/ADIPOQ/MBIP/HSPB1/CEP85/WWTR1/PTPN22/IPO7/DUSP6/DUSP2/TESC/RB1/FABP4/LYN/CEBPA/SH2B3/DVL1/MVP/IL1B	49
BP	GO:0090068	positive regulation of cell cycle process	55/2112	298/18670	0.0001692	0.001974	0.001426	TFDP2/IGF1/BTC/DTL/CCND2/NUSAP1/UBE2C/NDC80/CRLF3/MAD2L1/EGFR/CDC14B/UBE2B/CDC45/E2F8/SPHK1/CDC25B/KIF3B/TPR/SMARCD3/CDK1/DLGAP5/EZH2/LRP5/PBX1/DAZL/FEN1/CSPP1/HYAL1/ATRX/PLK2/RACGAP1/BRD4/ECT2/CDC7/SSTR5/CCNB1/MECP2/CCND1/DBF4/FBXO5/NIPBL/PAF1/AURKB/RB1/CUL4B/PKD2/KIF20B/PRMT1/PCBP4/TP53/AURKA/IL1B/PML/KIF23	55
BP	GO:2001251	negative regulation of chromosome organization	32/2112	146/18670	0.0001699	0.001978	0.001429	PTTG1/SKI/PTTG3P/BUB1/NDC80/MAD2L1/PLK1/UBE2B/TAF7/TPR/ZNF207/BUB1B/TOP2A/DNMT1/ATRX/PAX5/MCM2/CCNB1/MTF2/TERF1/FBXO5/PARP1/SPI1/CENPF/TTK/JARID2/AURKB/CDC20/HMGA1/ERCC1/SETMAR/TRIP13	32
BP	GO:0007260	tyrosine phosphorylation of STAT protein	22/2112	86/18670	0.0001731	0.002011	0.001453	CCL5/CRLF1/IGF1/IL15/PPP2CA/PTPN2/HCLS1/JAK2/CD40/SOCS1/GHR/LEP/IL6ST/IFNG/PECAM1/FLT3/CTF1/IL6/FER/IL18/LYN/SH2B3	22
BP	GO:0032648	regulation of interferon-beta production	15/2112	48/18670	0.0001737	0.002011	0.001453	TRAF3/RELB/IRF1/TLR8/ZBTB20/TLR2/IRF7/NMI/IFIH1/RIPK2/DDX58/PTPRS/PTPN11/TRIM38/LILRB1	15
BP	GO:1903727	positive regulation of phospholipid metabolic process	15/2112	48/18670	0.0001737	0.002011	0.001453	CCL19/CCR7/NOD2/HTR2B/FGR/FGF2/CCL21/HTR2A/CD19/FLT3/FPR2/PRKD1/LYN/CD81/VAV3	15
BP	GO:0010950	positive regulation of endopeptidase activity	37/2112	178/18670	0.0001751	0.002023	0.001462	AIM2/LCK/S100A9/BID/TNFSF10/LGALS9/MALT1/JAK2/PSME1/RIPK2/DLC1/DAP/CASP10/CLEC7A/CR1/BAK1/ASPH/NDUFA13/ARL6IP5/CASP1/PMAIP1/ADRM1/CYFIP2/SMAD3/FAM162A/VCP/CASP5/PPM1F/SYK/APAF1/LYN/NOD1/CASP4/GSN/PML/CTSH/NLRP3	37
BP	GO:0045637	regulation of myeloid cell differentiation	48/2112	251/18670	0.0001813	0.002091	0.001511	KITLG/PIK3R1/SFRP1/RBFOX2/STAT1/PRKCQ/ZBTB16/INHBA/MEIS1/PRKCB/CD74/PTPN2/HCLS1/IRF7/LILRB3/GATA2/MEIS2/EVI2B/CREBBP/KMT2A/GPR171/CCR1/LILRB4/NFKBIA/NCKAP1L/LEF1/CA2/P4HTM/ZFP36L1/IFNG/ARNT/ADIPOQ/TRIM58/SPI1/PAF1/INPP5D/TESC/FOXO3/MYL9/RB1/LYN/FSTL3/GP1BA/PRMT1/TOB2/ISG15/HOXA5/LILRB1	48
BP	GO:1903531	negative regulation of secretion by cell	42/2112	211/18670	0.0001827	0.002103	0.001519	SFRP1/TNFAIP3/CCR2/GBP1/IL27RA/TLR8/HLA-F/TNFRSF1B/RHBDF2/INHBA/PPP3CA/CD200/ANGPT1/LGALS9/BTN2A2/SRGN/KLF7/IDH2/NMB/IL13RA2/RAB33B/RHBDF1/PTPN11/NOTCH1/LEP/PTGER4/ADIPOQ/SERPINB1/TNFRSF4/MAOB/PTPN22/ANXA4/NR1H3/PPP1R11/HADH/LRRC32/TLR6/IL1B/PML/RAB11FIP1/LILRB1/NLRP3	42
BP	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	20/2112	75/18670	0.0001836	0.00211	0.001525	PSMB9/TAP1/TAPBP/PSMB8/HLA-F/HLA-A/PSMB10/TAP2/HLA-C/HLA-G/CD36/PSME1/HLA-E/HLA-B/FCGR1B/NCF4/IKBKG/CYBA/NCF1/ITGAV	20
BP	GO:0031099	regeneration	40/2112	198/18670	0.0001857	0.002123	0.001534	LCP1/IGF1/GLI3/PPP3CA/SGCA/JAM3/AXL/DYSF/JAK2/ANXA3/YAP1/EGFR/DAG1/TGFBR3/CDK1/BAK1/HGF/CCNA2/EZH2/SOX2/SCARF1/PTPRF/PTN/PTPRS/FZD7/CD9/NOTCH1/CCNB1/RGN/CPQ/FLT3/CCND1/TEC/HFE/MAP1B/TYMS/CD81/CFLAR/AURKA/GSN	40
BP	GO:0030038	contractile actin filament bundle assembly	24/2112	98/18670	0.0001858	0.002123	0.001534	PIK3R1/SFRP1/LIMCH1/LPAR1/PFN2/ITGB1BP1/DLC1/TAC1/WAS/NOX4/ARHGEF10/SMAD3/CORO2B/TNFAIP1/GPR65/MYOC/PPM1F/PTGER4/PAK1/SORBS1/TGFB3/WASF2/S1PR1/PFN1	24
BP	GO:0043149	stress fiber assembly	24/2112	98/18670	0.0001858	0.002123	0.001534	PIK3R1/SFRP1/LIMCH1/LPAR1/PFN2/ITGB1BP1/DLC1/TAC1/WAS/NOX4/ARHGEF10/SMAD3/CORO2B/TNFAIP1/GPR65/MYOC/PPM1F/PTGER4/PAK1/SORBS1/TGFB3/WASF2/S1PR1/PFN1	24
BP	GO:0006261	DNA-dependent DNA replication	33/2112	153/18670	0.0001867	0.002126	0.001536	LIG1/PURA/NUCKS1/ZNF365/BAZ1A/CDC45/BLM/E2F8/STAG2/MCM5/REV3L/RFC3/ZPR1/GINS1/FEN1/ATRX/DONSON/TIMELESS/CDC7/MCM2/TERF1/DBF4/FBXO5/POLE2/RNASEH2A/CDK2AP1/MCM4/HMGA1/GINS3/THOC1/SETMAR/CCNE2/MCM10	33
BP	GO:0050729	positive regulation of inflammatory response	33/2112	153/18670	0.0001867	0.002126	0.001536	CCR2/S100A9/IDO1/IL15/MYD88/CCR7/TLR2/NOD2/ADAM8/JAK2/CTSC/GPSM3/EGFR/HLA-E/CLEC7A/TAC1/NFKBIA/MAPK13/CCL18/CD6/IL6ST/AGTR1/PTGER4/BTK/IL6/IL18/FABP4/CEBPA/CD81/TGM2/PLA2G7/TLR6/IL1B	33
BP	GO:0014044	Schwann cell development	11/2112	29/18670	0.0001874	0.00213	0.001539	NTRK2/SKI/PARD3/DAG1/FA2H/SOD1/ARHGEF10/ADAM22/MYOC/MPP5/SH3TC2	11
BP	GO:0046394	carboxylic acid biosynthetic process	78/2112	462/18670	0.0001878	0.002131	0.00154	BHMT2/IGF1/CDO1/GCH1/IDO1/LTC4S/ZBTB20/PLP1/SERINC3/KYNU/AKR1C3/ACADVL/CD74/ACOX2/SLC2A6/CBS/CBFA2T3/NUP93/HDAC4/OAT/HK3/ALDOC/DCN/BGN/SLC1A3/TPR/CSPG4/ASPA/ERLIN1/FA2H/PER2/HPGDS/NUP160/ACACB/NAALAD2/NFKB1/HTR2A/VCAN/HYAL1/GPX4/HSD17B12/SUCLA2/UGDH/LIPG/PSPH/IFNG/ARNT/KMO/RGN/ADIPOQ/SYK/ERLIN2/FABP5/PDK4/PTGS1/UGP2/ELOVL4/DHRS9/NR1H3/OSBPL1A/FOLH1/SLC27A5/CYP46A1/ACADL/OSBPL9/NUP88/ELOVL2/AASS/ACSM5/ACSM3/LIPC/NUP50/TP53/PRKAB1/IL1B/EPHX2/ALOX5/ELOVL5	78
BP	GO:0046822	regulation of nucleocytoplasmic transport	25/2112	104/18670	0.0001888	0.002137	0.001544	PIK3R1/BMP4/ZIC1/PTPN14/GLI3/ANGPT1/HCLS1/MX2/CD36/IFI27/CPSF6/TPR/BARD1/TCF7L2/ZPR1/SMAD3/PTPN11/ECT2/LEP/IFNG/FERMT1/TP53/KHDRBS1/IL1B/XPO4	25
BP	GO:0006661	phosphatidylinositol biosynthetic process	27/2112	116/18670	0.0001894	0.002137	0.001544	PLEKHA1/PIK3R1/PIGK/PIP4K2B/HTR2B/FGF2/SH3YL1/DPM3/PLCG2/GPAA1/MTMR14/PIK3CD/PIGH/PLEKHA4/HTR2A/PTPN13/PIK3CA/PIGP/PLEKHA2/PIK3R3/INPP5D/PIP4K2A/FPR2/PIGT/PIGF/MTMR2/RAB14	27
BP	GO:0021782	glial cell development	27/2112	116/18670	0.0001894	0.002137	0.001544	WASF3/CLU/PLP1/NTRK2/SKI/PARD3/LPAR1/TLR2/MXRA8/EGFR/DAG1/ASPA/FA2H/SOD1/ARHGEF10/ADAM22/CD9/MYOC/IFNG/IL6/FPR2/LYN/MPP5/TENM4/SH3TC2/GSN/IL1B	27
BP	GO:0033157	regulation of intracellular protein transport	44/2112	225/18670	0.0001973	0.002218	0.001602	LCP1/PIK3R1/BMP4/ZIC1/PTPN14/RAC2/GLI3/ANGPT1/HCLS1/ITGB1BP1/ITGB2/CD36/IFI27/TPR/BARD1/ERBB2/TCF7L2/ZPR1/SMAD3/EDEM1/PTPN11/ECT2/GDI1/LEP/IFNG/PAK1/MYO1C/ADIPOQ/ZFAND1/VAMP2/PINK1/UBE2J1/FERMT1/HSPA1L/KIF20B/CD81/EDEM2/SH3TC2/PRR5L/TP53/BNIP3L/IL1B/UBE2G2/XPO4	44
BP	GO:0045665	negative regulation of neuron differentiation	44/2112	225/18670	0.0001973	0.002218	0.001602	SEMA4A/ASPM/SOX9/SEMA4D/GLI3/SEMA3A/PPP3CA/SPOCK1/MEIS1/LPAR1/ZNF365/GAK/TRAK2/PMP22/FGF13/NLGN1/SOX2/ID3/PBX1/RYK/PTPRS/SEMA3F/DIXDC1/PLK2/NOTCH1/GDI1/KANK1/MYLIP/DPYSL3/EDNRB/GFI1/ARHGAP4/CD38/ZHX2/BCL11A/SEMA4F/FOXO3/SEMA3E/DDX6/HEY1/DIO3/BAG5/SEMA6B/FEZF2	44
BP	GO:0032732	positive regulation of interleukin-1 production	17/2112	59/18670	0.0001997	0.002237	0.001616	AIM2/TLR8/CCL19/LGALS9/NOD2/MALT1/JAK2/RIPK2/CLEC7A/CASP1/SMAD3/MNDA/IFNG/HSPB1/NOD1/PANX1/NLRP3	17
BP	GO:2000351	regulation of endothelial cell apoptotic process	17/2112	59/18670	0.0001997	0.002237	0.001616	NDNF/TNFAIP3/ITGA4/AKR1C3/ANGPT1/HLA-G/ICAM1/TNIP2/CD40/SCG2/GATA2/CD160/CD40LG/ANGPTL4/FOXO3/KDR/CCL2	17
BP	GO:0016053	organic acid biosynthetic process	78/2112	463/18670	0.0002014	0.002252	0.001627	BHMT2/IGF1/CDO1/GCH1/IDO1/LTC4S/ZBTB20/PLP1/SERINC3/KYNU/AKR1C3/ACADVL/CD74/ACOX2/SLC2A6/CBS/CBFA2T3/NUP93/HDAC4/OAT/HK3/ALDOC/DCN/BGN/SLC1A3/TPR/CSPG4/ASPA/ERLIN1/FA2H/PER2/HPGDS/NUP160/ACACB/NAALAD2/NFKB1/HTR2A/VCAN/HYAL1/GPX4/HSD17B12/SUCLA2/UGDH/LIPG/PSPH/IFNG/ARNT/KMO/RGN/ADIPOQ/SYK/ERLIN2/FABP5/PDK4/PTGS1/UGP2/ELOVL4/DHRS9/NR1H3/OSBPL1A/FOLH1/SLC27A5/CYP46A1/ACADL/OSBPL9/NUP88/ELOVL2/AASS/ACSM5/ACSM3/LIPC/NUP50/TP53/PRKAB1/IL1B/EPHX2/ALOX5/ELOVL5	78
BP	GO:0061448	connective tissue development	51/2112	273/18670	0.0002114	0.002359	0.001704	FTO/GDF5/BMP4/LRP6/RUNX3/SCARA3/WNT5B/MGP/TRPS1/PTHLH/FGF18/SOX9/ZBTB16/GLI3/LTBP3/OXCT1/SOX5/SULF1/COCH/BMPR1A/PDGFD/SIX2/COMP/SHOX2/KLF7/FGF2/NFIB/COL14A1/CREB3L2/GLG1/ACAT1/HOXC4/CHST11/LUM/LRP5/PITX1/EFEMP1/HYAL1/SMAD3/TNMD/NOTCH1/LEP/PIK3CA/FGF9/TYMS/CFLAR/PTH1R/HOXA11/GPR4/HOXA5/THRA	51
BP	GO:1990845	adaptive thermogenesis	33/2112	154/18670	0.0002122	0.002364	0.001708	CCR2/HOXC10/CXCR4/IL15/IRF4/IL4R/DIO2/NOVA1/JAK2/CD36/PLAC8/TRPV2/PER2/NOTCH1/ARNTL/LEP/ADIPOQ/SYK/FABP5/G0S2/DDIT3/NR1H3/UCP2/RB1/IL18/FABP4/ABHD6/ACADL/HADH/NPR3/PRKAB1/YBX2/THRA	33
BP	GO:0045066	regulatory T cell differentiation	12/2112	34/18670	0.0002137	0.002376	0.001717	PLA2G2D/CTLA4/IRF1/LILRB2/HLA-G/LGALS9/SOCS1/BTN2A2/CR1/LILRB4/IFNG/IL2RA	12
BP	GO:0050678	regulation of epithelial cell proliferation	66/2112	378/18670	0.0002177	0.002416	0.001746	CCL5/SFRP1/TNFAIP3/GDF5/BMP4/BCL11B/RUNX3/CDKN1C/IGF1/STAT1/SOX9/ITGA4/FGF7/HTRA1/AR/SULF1/SIX1/NOD2/BMPR1A/DYSF/PRKD2/HTR2B/SCG2/YAP1/GATA2/EGFR/FGF2/TGFBR3/THBS4/NFIB/ERBB2/SP1/TCF7L2/SOX2/PPP1R16B/PTN/TP63/HYAL1/SMAD3/TNMD/FZD7/NOTCH1/LEP/ZFP36L1/AGTR1/ARNT/RGN/PRL/CCND1/APLNR/EDNRB/FGF9/AKT3/RB1/CYBA/VEGFB/PRKD1/ANG/KDR/CFLAR/CCL2/EAF2/CASK/LIMS2/MMP12/HOXA5	66
BP	GO:0002792	negative regulation of peptide secretion	32/2112	148/18670	0.0002211	0.002441	0.001764	SFRP1/TNFAIP3/GBP1/IL27RA/TLR8/RHBDF2/PPP3CA/CD200/ANGPT1/CD74/BTN2A2/SRGN/KLF7/IDH2/RHBDF1/PTPN11/LEP/PTGER4/SERPINB1/TNFRSF4/PTPN22/ANXA4/NR1H3/PPP1R11/HADH/LRRC32/TLR6/IL1B/PML/RAB11FIP1/LILRB1/NLRP3	32
BP	GO:0035107	appendage morphogenesis	32/2112	148/18670	0.0002211	0.002441	0.001764	GDF5/BMP4/LRP6/HOXC10/HOXA10/TMEM231/SOX9/ZBTB16/GLI3/SKI/BMPR1A/SHOX2/ZNF358/RECK/CREBBP/BAK1/ASPH/CHST11/TP63/PITX1/PBX1/LEF1/ATRX/NOTCH1/TFAP2A/FGF9/HOXD10/NIPBL/TULP3/FZD6/MEGF8/HOXA11	32
BP	GO:0035108	limb morphogenesis	32/2112	148/18670	0.0002211	0.002441	0.001764	GDF5/BMP4/LRP6/HOXC10/HOXA10/TMEM231/SOX9/ZBTB16/GLI3/SKI/BMPR1A/SHOX2/ZNF358/RECK/CREBBP/BAK1/ASPH/CHST11/TP63/PITX1/PBX1/LEF1/ATRX/NOTCH1/TFAP2A/FGF9/HOXD10/NIPBL/TULP3/FZD6/MEGF8/HOXA11	32
BP	GO:0010761	fibroblast migration	13/2112	39/18670	0.0002269	0.002501	0.001807	DDR2/ITGB1BP1/SGPL1/TNS1/FGF2/AKAP12/C5orf30/SLC8A1/PAK1/ARHGAP4/FER/PRR5L/PML	13
BP	GO:0006026	aminoglycan catabolic process	18/2112	65/18670	0.0002276	0.002504	0.001809	PRELP/FMOD/GPC5/OGN/HMMR/FGF2/LYVE1/DCN/BGN/CSPG4/LUM/VCAN/HYAL1/IDUA/FUCA1/GPC4/OVGP1/STAB2	18
BP	GO:0042269	regulation of natural killer cell mediated cytotoxicity	14/2112	44/18670	0.0002296	0.002521	0.001822	RASGRP1/HLA-F/HLA-G/LGALS9/MICB/CRTAM/HLA-E/SH2D1A/CD160/CD226/CADM1/VAV1/LEP/LILRB1	14
BP	GO:0003012	muscle system process	78/2112	465/18670	0.0002313	0.002536	0.001832	SSPN/IGFBP5/IGF1/TNFRSF1B/PLCE1/CXCR4/SYNM/IL15/TMOD1/SRI/CACNA2D1/ANK2/PPP3CA/SGCA/SULF1/FXYD1/CRYAB/DYSF/HDAC4/COMP/HTR2B/ADA/KCNJ5/SPHK1/CALD1/GTF2IRD2B/EZH2/SORBS2/PLN/ASPH/PDLIM5/SOD1/SGCD/KCNJ2/HTR2A/ATP1B1/FOXO1/SMAD3/SCN1B/NOTCH1/KCNJ8/MYOC/LEP/IL6ST/GTF2IRD1/DSC2/LMOD1/ATP1A2/PIK3CA/MYL5/HEY2/SLC8A1/PAK1/EDNRB/SORBS1/PARP1/CTTN/AKAP13/CD38/PRKG1/JARID2/MYH11/FOXO3/LMNA/HSPB6/MYL9/CYBA/VEGFB/GSTO1/MYLK/GJC1/CFLAR/GSTM2/MYL6B/SNTA1/GSN/IL1B/GPD1L	78
BP	GO:1901342	regulation of vasculature development	72/2112	422/18670	0.0002369	0.002589	0.001871	CXCL13/SFRP1/TNFAIP3/CCR2/BMP4/SEMA4A/STAT1/FGF18/CXCR4/FOXC1/PRKCB/EMP2/ITGB1BP1/ITGB2/SULF1/HLA-G/PDGFD/CD40/PRKD2/ANXA3/GATA2/CXCL10/RECK/FGF2/SPHK1/THBS4/DCN/CXCL8/CD160/ERBB2/TMEM100/HGF/SP1/CX3CR1/PPP1R16B/PTN/RRAS/DNMT1/HYAL1/TNMD/ANGPTL4/PLK2/NOTCH1/LEP/AGTR1/MECP2/PRL/HEY2/APLNR/FGF9/ITGAX/HSPB1/AKT3/IL6/HSPB6/SEMA3E/ADAM10/VEGFB/PRKD1/PDE3B/HIPK2/HEY1/KDR/CFLAR/SPINK5/GPR4/IL1B/CDH5/HOXA5/PML/C6/CTSH	72
BP	GO:0046209	nitric oxide metabolic process	21/2112	82/18670	0.000237	0.002589	0.001871	CLU/GCH1/NQO1/TLR2/HBB/ITGB2/ICAM1/JAK2/CD36/DDAH2/CLEC7A/CX3CR1/SMAD3/IFNG/RGN/HSP90AB1/GLA/PKD2/TLR6/IL1B/PTX3	21
BP	GO:0050768	negative regulation of neurogenesis	54/2112	295/18670	0.000239	0.002607	0.001883	SEMA4A/ASPM/SOX9/SEMA4D/GLI3/SEMA3A/SKI/PPP3CA/SPOCK1/MEIS1/LPAR1/ZNF365/GAK/BMPR1A/TRAK2/PMP22/FGF13/IDH2/NLGN1/SOX2/ID3/PTN/PBX1/RYK/PTPRS/SEMA3F/DIXDC1/DAAM2/PLK2/NOTCH1/GDI1/KANK1/MYLIP/DPYSL3/EDNRB/GFI1/IL6/ARHGAP4/CD38/ZHX2/BCL11A/SEMA4F/FOXO3/SEMA3E/DDX6/HEY1/DIO3/BAG5/SEMA6B/RNF10/TP53/FEZF2/IL1B/BRINP1	54
BP	GO:1901990	regulation of mitotic cell cycle phase transition	75/2112	444/18670	0.0002433	0.002648	0.001913	PSMB9/CDKN2C/PSMB8/TFDP2/CDKN1C/PSMB10/DTL/CCND2/CETN2/BUB1/SKP1/BID/HMMR/UBE2C/NDC80/KANK2/MAD2L1/PLK1/TPX2/TUBA4A/PSME1/EGFR/CDC14B/BTN2A2/CDC45/PTPN6/BLM/E2F8/CDC25B/FHL1/TPR/SMARCD3/CDK1/DLGAP5/ZNF207/EZH2/CEP135/BUB1B/TUBB4A/PBX1/NEK2/HYAL1/PLK2/UBE2D1/BRD4/DONSON/CDC7/ZFP36L1/CCNB1/MECP2/DACT1/CCND1/FBXO5/CNTRL/CENPF/TTK/MIIP/AURKB/RB1/CEP63/CDC20/CUL4B/FBXL7/SYF2/PKD2/NAE1/ZFP36L2/PRMT1/PCBP4/TRIP13/TP53/CCL2/AURKA/TOPBP1/PML	75
BP	GO:1903725	regulation of phospholipid metabolic process	22/2112	88/18670	0.0002473	0.002687	0.001941	PIK3R1/CCL19/CCR7/NOD2/HTR2B/SOCS1/FGR/CISH/FGF2/CCL21/SOCS2/HTR2A/CD19/SOCS6/FLT3/PIK3R3/FPR2/PRKD1/LYN/CD81/MTMR2/VAV3	22
BP	GO:1904029	regulation of cyclin-dependent protein kinase activity	25/2112	106/18670	0.0002593	0.002812	0.002032	CDKN2C/TNFAIP3/CDKN1C/CCND2/CCNB2/PLK1/EGFR/DIRAS3/BLM/CCNT1/CCNA2/HERC5/CKS2/HEXIM1/CCNI/CCNB1/HSP90AB1/CCND1/CKS1B/IPO7/CEBPA/CCNG1/PKD2/CCNF/CCNE2	25
BP	GO:0044282	small molecule catabolic process	75/2112	445/18670	0.0002609	0.002823	0.00204	GK/TYMP/FAH/CDO1/NT5E/IDO1/ALDH7A1/GALT/PCYOX1/KYNU/ALDH3A2/AKR1C3/OXCT1/ACADVL/UPP1/ACOX2/HMMR/APOBEC3G/ALDH6A1/CBS/PCBD1/APOBEC3B/OAT/HK3/DDAH2/ADA/ESD/FGF2/ALDOC/LYVE1/MCCC1/ECHDC2/ASPA/ACAT1/SCARF1/PCK1/LRP5/ETFB/ACACB/INPP1/PGD/HYAL1/HPD/PCCA/MAT1A/IDUA/NAGK/LEP/BDH2/KMO/ECI2/ENTPD7/PNP/ADIPOQ/BDH1/ECI1/ADH5/ENTPD1/BCKDHB/ENTPD4/CYP46A1/ACADL/HAGH/FUT8/HADH/AASS/ECHS1/MTMR2/TP53/TKTL1/STAB2/FUT4/ALDH5A1/HADHA/TXN2	75
BP	GO:1901991	negative regulation of mitotic cell cycle phase transition	47/2112	248/18670	0.0002612	0.002823	0.00204	PSMB9/CDKN2C/PSMB8/TFDP2/PSMB10/BUB1/SKP1/NDC80/KANK2/MAD2L1/PLK1/PSME1/BTN2A2/BLM/E2F8/FHL1/TPR/CDK1/ZNF207/EZH2/BUB1B/PLK2/DONSON/ZFP36L1/CCNB1/DACT1/CCND1/FBXO5/CENPF/TTK/MIIP/AURKB/RB1/CDC20/FBXL7/SYF2/PKD2/NAE1/ZFP36L2/PRMT1/PCBP4/TRIP13/TP53/CCL2/AURKA/TOPBP1/PML	47
BP	GO:0010743	regulation of macrophage derived foam cell differentiation	11/2112	30/18670	0.0002658	0.002863	0.002069	PRKCH/ABCG1/CD36/NFKBIA/NFKB1/AGTR1/ADIPOQ/CETP/NR1H3/IL18/ITGAV	11
BP	GO:1902751	positive regulation of cell cycle G2/M phase transition	11/2112	30/18670	0.0002658	0.002863	0.002069	DTL/CDC25B/SMARCD3/CDK1/PBX1/BRD4/CDC7/CCNB1/MECP2/CCND1/FBXO5	11
BP	GO:0071559	response to transforming growth factor beta	48/2112	255/18670	0.0002663	0.002863	0.002069	XCL1/SFRP1/GDF5/RUNX3/FMOD/CDKN1C/PENK/SOX9/LTBP3/SKI/PARD3/ARHGEF18/ZFHX3/SOX5/HTRA1/FERMT2/CILP/LTBP2/BMPR1A/ADAMTSL2/PDGFD/TWSG1/TGFBR3/CREBBP/GLG1/CX3CR1/CHST11/NOX4/PMEPA1/SMAD3/LDLRAD4/ZFP36L1/HSP90AB1/ACVR1/PARP1/TGFB3/APAF1/NLK/FERMT1/HIPK2/DKK3/FUT8/CFLAR/ZFP36L2/LRRC32/TP53/CDH5/PML	48
BP	GO:0006809	nitric oxide biosynthetic process	20/2112	77/18670	0.0002697	0.002894	0.002091	CLU/GCH1/NQO1/HBB/ITGB2/ICAM1/JAK2/CD36/DDAH2/CLEC7A/CX3CR1/SMAD3/IFNG/RGN/HSP90AB1/GLA/PKD2/TLR6/IL1B/PTX3	20
BP	GO:0044273	sulfur compound catabolic process	16/2112	55/18670	0.0002701	0.002894	0.002091	PRELP/FMOD/CDO1/PCYOX1/OGN/CBS/DCN/BGN/CSPG4/ACAT1/LUM/VCAN/HYAL1/MAT1A/IDUA/TXN2	16
BP	GO:0046425	regulation of JAK-STAT cascade	30/2112	137/18670	0.0002717	0.002906	0.0021	CCL5/PTPRC/CRLF1/IGF1/IL15/PPP2CA/PTPN2/HCLS1/CRLF3/JAK2/CD40/SOCS1/AKR1B1/GHR/SOCS2/NOTCH1/LEP/IL6ST/IFNG/PECAM1/PRL/FLT3/IL10RA/CTF1/IL6/NLK/IL18/LYN/SH2B3/IFNA1	30
BP	GO:0048660	regulation of smooth muscle cell proliferation	35/2112	169/18670	0.0002782	0.002966	0.002143	CCL5/TNFAIP3/BMP4/IGFBP5/IGF1/STAT1/IL15/OGN/ABCC4/BMPR1A/JAK2/PDGFD/HDAC4/AKR1B1/EGFR/HBEGF/FGF2/PDE1A/TCF7L2/DNMT1/IFNG/PAK1/ADIPOQ/P2RY6/FGF9/TGFB3/IL6/PRKG1/CYBA/IL18/ANG/NPR3/S1PR1/TGM2/NDRG2	35
BP	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	42/2112	215/18670	0.0002786	0.002966	0.002143	LAMP3/LCK/S100A9/TNFAIP8/BIRC3/BID/TNFSF10/LGALS9/MALT1/CRYAB/JAK2/RPS6KA1/DLC1/DAP/CASP10/CLEC7A/BAK1/HGF/SOX2/CD27/TP63/NDUFA13/ARL6IP5/CASP1/PMAIP1/LEF1/SMAD3/FAM162A/VCP/CASP5/MICAL1/PPM1F/SYK/APAF1/NOD1/NLE1/CFLAR/CASP4/GSN/PML/CTSH/NLRP3	42
BP	GO:0061138	morphogenesis of a branching epithelium	37/2112	182/18670	0.0002787	0.002966	0.002143	SFRP1/BMP4/LRP6/DLG5/SOX9/GLI3/SEMA3A/FGF7/RASIP1/AR/SULF1/SIX1/SIX2/YAP1/DAG1/FGF2/ETV5/SPINT2/HGF/LRP5/TP63/PBX1/DCHS1/LEF1/NOTCH1/TIMELESS/PPP1CA/PAK1/ACVR1/FAT4/SEMA3E/PKD2/TGM2/HOXA11/HOXA5/PML/CTSH	37
BP	GO:0045428	regulation of nitric oxide biosynthetic process	18/2112	66/18670	0.0002802	0.002977	0.002151	CLU/HBB/ITGB2/ICAM1/JAK2/CD36/DDAH2/CLEC7A/CX3CR1/SMAD3/IFNG/RGN/HSP90AB1/GLA/PKD2/TLR6/IL1B/PTX3	18
BP	GO:0042509	regulation of tyrosine phosphorylation of STAT protein	21/2112	83/18670	0.0002839	0.003011	0.002176	CCL5/CRLF1/IGF1/IL15/PPP2CA/PTPN2/HCLS1/JAK2/CD40/SOCS1/GHR/LEP/IL6ST/IFNG/PECAM1/FLT3/CTF1/IL6/IL18/LYN/SH2B3	21
BP	GO:0032608	interferon-beta production	15/2112	50/18670	0.0002873	0.003042	0.002198	TRAF3/RELB/IRF1/TLR8/ZBTB20/TLR2/IRF7/NMI/IFIH1/RIPK2/DDX58/PTPRS/PTPN11/TRIM38/LILRB1	15
BP	GO:0030326	embryonic limb morphogenesis	28/2112	125/18670	0.0002885	0.003044	0.002199	GDF5/BMP4/LRP6/HOXC10/HOXA10/TMEM231/ZBTB16/GLI3/SKI/BMPR1A/SHOX2/ZNF358/RECK/CREBBP/CHST11/TP63/PITX1/PBX1/LEF1/NOTCH1/TFAP2A/FGF9/HOXD10/NIPBL/TULP3/FZD6/MEGF8/HOXA11	28
BP	GO:0035113	embryonic appendage morphogenesis	28/2112	125/18670	0.0002885	0.003044	0.002199	GDF5/BMP4/LRP6/HOXC10/HOXA10/TMEM231/ZBTB16/GLI3/SKI/BMPR1A/SHOX2/ZNF358/RECK/CREBBP/CHST11/TP63/PITX1/PBX1/LEF1/NOTCH1/TFAP2A/FGF9/HOXD10/NIPBL/TULP3/FZD6/MEGF8/HOXA11	28
BP	GO:0001787	natural killer cell proliferation	6/2112	10/18670	0.0002915	0.003066	0.002215	IL15/ELF4/HLA-E/LEP/PTPN22/IL18	6
BP	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	6/2112	10/18670	0.0002915	0.003066	0.002215	ICAM1/LGALS9/ITGAL/HLA-DMB/CD81/LILRB1	6
BP	GO:0071229	cellular response to acid chemical	41/2112	209/18670	0.0002985	0.003133	0.002264	PID1/SFRP1/EPHA3/WNT5B/SOX9/SIPA1/NTRK2/AKR1C3/SIX1/PDGFD/SOCS1/YAP1/EGFR/CPEB1/AKR1C1/PCK1/ID3/LANCL2/NDUFA13/FZD4/DNMT1/FZD7/LEP/CCNB1/OR51E2/PTGFR/PTGER4/SMARCD1/P2RY6/PDK4/PINK1/BCL11A/TESC/CYBA/SESN1/LYN/KDR/PKD2/COL16A1/P2RY4/BRINP1	41
BP	GO:0045069	regulation of viral genome replication	23/2112	95/18670	3e-04	0.003144	0.002272	CCL5/SLPI/NUCKS1/APOBEC3G/OAS1/ISG20/SRPK1/IFI27/OASL/CXCL8/FAM111A/TOP2A/NOTCH1/FBXL2/ADAR/MPHOSPH8/OAS3/TRIM38/IFIT5/PLSCR1/MX1/ZC3HAV1/ISG15	23
BP	GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	13/2112	40/18670	0.0003017	0.003156	0.00228	XCL1/PTPRC/IL27RA/HLA-F/IL7R/IL4R/HLA-G/PTPN6/CR1/TBX21/HFE/THOC1/LILRB1	13
BP	GO:1903426	regulation of reactive oxygen species biosynthetic process	24/2112	101/18670	0.0003027	0.003162	0.002285	CLU/HBB/ITGB2/ICAM1/JAK2/CD36/HDAC4/SLC18A2/DDAH2/CLEC7A/CX3CR1/SMAD3/RAB27A/IFNG/RGN/HSP90AB1/GLA/FOXO3/CYBA/PKD2/CFLAR/TLR6/IL1B/PTX3	24
BP	GO:0021700	developmental maturation	52/2112	284/18670	0.0003065	0.003194	0.002308	CDKN1C/IGF1/CCL19/IL15/SEMA4D/AXL/NPR2/GATA2/RECK/DAG1/CDC25B/CLEC7A/CCL21/CX3CR1/CLSTN1/SCARF1/DAZL/DCHS1/IRX5/MYOC/LEP/CCNB1/MECP2/EDNRB/FBXO5/TRIM58/STXBP1/BTK/REC8/MAP1B/SYBU/FAT4/TYMS/BCL11A/DDIT3/FOXO3/RB1/FERMT1/CDC20/MBTPS2/ANG/CEBPA/REN/SPINK5/S1PR1/PTH1R/TRIP13/PFN1/AURKA/PTBP3/CDH5/HOXA5	52
BP	GO:0001763	morphogenesis of a branching structure	39/2112	196/18670	0.0003069	0.003194	0.002308	SFRP1/BMP4/LRP6/DLG5/SOX9/GLI3/SEMA3A/FGF7/RASIP1/AR/SULF1/SIX1/SIX2/SHOX2/YAP1/DAG1/FGF2/ETV5/SPINT2/HGF/LRP5/TP63/PBX1/DCHS1/LEF1/NOTCH1/TIMELESS/PPP1CA/PAK1/ACVR1/FAT4/BCL11A/SEMA3E/PKD2/TGM2/HOXA11/HOXA5/PML/CTSH	39
BP	GO:0000075	cell cycle checkpoint	42/2112	216/18670	0.0003087	0.003208	0.002318	TFDP2/DTL/BUB1/NDC80/MAD2L1/PLK1/CDC14B/CDC45/CHFR/BLM/E2F8/RPL24/TPR/CDK1/ZNF207/BUB1B/TOP2A/PTPN11/PLK2/DONSON/ZWINT/TIMELESS/CCNB1/CCND1/CENPF/TTK/AURKB/RB1/CEP63/CDC20/SYF2/NAE1/THOC1/PRMT1/SETMAR/PCBP4/WAC/TRIP13/TP53/AURKA/TOPBP1/PML	42
BP	GO:0006027	glycosaminoglycan catabolic process	17/2112	61/18670	0.00031	0.003216	0.002324	PRELP/FMOD/GPC5/OGN/HMMR/FGF2/LYVE1/DCN/BGN/CSPG4/LUM/VCAN/HYAL1/IDUA/FUCA1/GPC4/STAB2	17
BP	GO:0022604	regulation of cell morphogenesis	80/2112	484/18670	0.0003116	0.003227	0.002332	WASF3/GBP1/CORO1A/SEMA4A/PLEKHO1/MYH10/CXCR4/ARPIN/SEMA4D/NTRK2/SEMA3A/CCL13/PPP3CA/ARHGEF18/LPAR1/RHOBTB3/ITGB1BP1/ITGB2/FERMT2/PTPRD/ICAM1/COCH/TRAK2/RHOF/SHOX2/FGR/TUBB2B/PDPN/DAG1/DLC1/FGF13/TRPV2/CDC42EP3/S100A13/RHOH/NLGN1/PTN/PDLIM5/DOCK1/CDH2/PARVA/RYK/PTPRS/FZD4/SEMA3F/EFNA5/CHN1/MYOC/GDI1/KANK1/RHOG/SYT17/CCL7/PAK1/CTTN/RHOD/CHODL/MAP1B/ARHGAP4/MEGF8/BCL11A/LST1/DPYSL2/CFL1/SEMA4F/AP1AR/FBLN1/SEMA3E/ADAM10/KDR/HCK/DVL1/WDR1/SEMA6B/ABI2/CCL2/FEZF2/PALMD/LIMS2/ACTR2	80
BP	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	29/2112	132/18670	0.0003214	0.003322	0.0024	LCK/S100A9/BID/TNFSF10/LGALS9/MALT1/JAK2/DLC1/DAP/CASP10/CLEC7A/BAK1/NDUFA13/ARL6IP5/CASP1/PMAIP1/SMAD3/FAM162A/VCP/CASP5/PPM1F/SYK/APAF1/NOD1/CASP4/GSN/PML/CTSH/NLRP3	29
BP	GO:0001556	oocyte maturation	10/2112	26/18670	0.0003218	0.003322	0.0024	NPR2/CDC25B/DAZL/CCNB1/FBXO5/REC8/FOXO3/ANG/TRIP13/AURKA	10
BP	GO:0045667	regulation of osteoblast differentiation	28/2112	126/18670	0.0003316	0.003417	0.002469	NELL1/SFRP1/BMP4/IGFBP5/IGF1/DDR2/ZHX3/SEMA4D/GLI3/SKI/TCIRG1/BMPR1A/HDAC4/TWSG1/HGF/ID3/LRP5/TP63/SMAD3/NOTCH1/IL6ST/TOB1/ACVR1/FBXO5/IL6/PRKD1/CEBPA/ATRAID	28
BP	GO:0007599	hemostasis	60/2112	341/18670	0.0003344	0.003441	0.002486	SERPINA1/LCK/PIK3R1/IRF1/PRKCH/PRKCQ/FLI1/SERPINA5/SH2B2/PRKCB/AXL/LCP2/HBB/ZFPM2/JAK2/CD36/CD40/COMP/IRF2/GATA2/PDPN/PTPN6/PROS1/F5/PROCR/PLCG2/WAS/PLEK/VKORC1/CD40LG/PLAT/DOCK1/RAB27A/PTPN11/VAV1/CD9/HBD/DGKA/PIK3CA/MICAL1/SYK/AKAP1/TEC/STXBP1/HSPB1/IL6/FZD6/PRKG1/ENTPD1/PLSCR1/CAPZA1/FBLN1/MYL9/TFPI/LYN/SH2B3/MERTK/GP1BA/IFNA1/VAV3	60
BP	GO:0002698	negative regulation of immune effector process	27/2112	120/18670	0.0003403	0.003489	0.002521	SLAMF8/XCL1/PTPRC/CCR2/HLA-F/IL7R/ANGPT1/HTRA1/IL4R/HLA-G/LGALS9/CD96/MICB/HLA-E/TSPAN6/PTPN6/CR1/TBX21/IL13RA2/HFE/TGFB3/FER/TRIM38/SPINK5/THOC1/IL2RA/LILRB1	27
BP	GO:0022612	gland morphogenesis	27/2112	120/18670	0.0003403	0.003489	0.002521	SFRP1/TNFAIP3/BMP4/IGFBP5/LRP6/SOX9/GLI3/SEMA3A/FGF7/AR/SULF1/TWSG1/RPS6KA1/EGFR/DAG1/ETV5/NFIB/HGF/PTN/LRP5/TP63/NOTCH1/TGFB3/CFLAR/TGM2/LIMS2/PML	27
BP	GO:0043393	regulation of protein binding	42/2112	217/18670	0.0003418	0.003499	0.002528	BMP4/ITGA4/SLPI/PPP2CA/CDON/ANGPT1/ITGB1BP1/PCBD1/GOLGA2/PLK1/CD36/HDAC4/RIPK2/TGFBR3/DZIP1/SPON1/SMARCD3/BAG2/BAK1/TCF7L2/PTPRF/CCPG1/PPP2CB/LRPAP1/LEF1/PLK2/GTF2F1/PPP1CA/HSP90AB1/ADIPOQ/DACT1/HFE/CRBN/LDOC1/AURKB/CRTAC1/HIPK2/DVL1/IFIT2/PIM2/CCL23/AURKA	42
BP	GO:0048659	smooth muscle cell proliferation	35/2112	171/18670	0.0003514	0.003591	0.002595	CCL5/TNFAIP3/BMP4/IGFBP5/IGF1/STAT1/IL15/OGN/ABCC4/BMPR1A/JAK2/PDGFD/HDAC4/AKR1B1/EGFR/HBEGF/FGF2/PDE1A/TCF7L2/DNMT1/IFNG/PAK1/ADIPOQ/P2RY6/FGF9/TGFB3/IL6/PRKG1/CYBA/IL18/ANG/NPR3/S1PR1/TGM2/NDRG2	35
BP	GO:0051225	spindle assembly	25/2112	108/18670	0.000352	0.003592	0.002595	ASPM/MAPRE2/GOLGA2/PLK1/TPX2/KIF11/KIF3B/TPR/MAP9/ZNF207/STAG2/KIF4A/NEK7/ARHGEF10/NEK2/RACGAP1/FBXO5/CHMP2B/AURKB/CEP63/CDC20/AURKA/KIFC1/CHMP1B/KIF23	25
BP	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	24/2112	102/18670	0.0003541	0.003607	0.002606	CDKN2C/TNFAIP3/CDKN1C/CCND2/CCNB2/PLK1/EGFR/DIRAS3/BLM/CCNT1/CCNA2/HERC5/CKS2/HEXIM1/CCNI/CCNB1/CCND1/CKS1B/IPO7/CEBPA/CCNG1/PKD2/CCNF/CCNE2	24
BP	GO:0007202	activation of phospholipase C activity	11/2112	31/18670	0.0003702	0.003764	0.00272	ITK/NTRK2/LPAR1/HTR2B/EGFR/SELE/TXK/HTR2A/P2RY6/ANG/S1PR4	11
BP	GO:0007093	mitotic cell cycle checkpoint	34/2112	165/18670	0.000372	0.003777	0.002729	TFDP2/BUB1/NDC80/MAD2L1/PLK1/CHFR/BLM/E2F8/RPL24/TPR/CDK1/ZNF207/BUB1B/TOP2A/PLK2/DONSON/ZWINT/CCNB1/CCND1/CENPF/TTK/AURKB/RB1/CDC20/SYF2/NAE1/PRMT1/SETMAR/PCBP4/TRIP13/TP53/AURKA/TOPBP1/PML	34
BP	GO:0031342	negative regulation of cell killing	9/2112	22/18670	0.0003739	0.003777	0.002729	PTPRC/HLA-F/IL7R/HLA-G/LGALS9/HLA-E/HSP90AB1/KRT6A/LILRB1	9
BP	GO:0042094	interleukin-2 biosynthetic process	9/2112	22/18670	0.0003739	0.003777	0.002729	CD3E/PTPRC/PRKCQ/IRF4/CLEC7A/CD86/CD80/IL18/IL1B	9
BP	GO:0072643	interferon-gamma secretion	9/2112	22/18670	0.0003739	0.003777	0.002729	CD2/RASGRP1/TCIRG1/LGALS9/CD160/BTN3A1/PTPN22/ISG15/LILRB1	9
BP	GO:1904892	regulation of STAT cascade	31/2112	146/18670	0.0003845	0.003878	0.002802	CCL5/PTPRC/CRLF1/IGF1/IL15/IL7R/PPP2CA/PTPN2/HCLS1/CRLF3/JAK2/CD40/SOCS1/AKR1B1/GHR/SOCS2/NOTCH1/LEP/IL6ST/IFNG/PECAM1/PRL/FLT3/IL10RA/CTF1/IL6/NLK/IL18/LYN/SH2B3/IFNA1	31
BP	GO:0001649	osteoblast differentiation	43/2112	225/18670	0.0003879	0.003906	0.002822	NELL1/SFRP1/BMP4/IGFBP5/IGF1/DDR2/ZHX3/PENK/PTHLH/SEMA4D/GLI3/SKI/TCIRG1/BMPR1A/HDAC4/SHOX2/TWSG1/MRC2/HGF/SOX2/ID3/LRP5/TP63/VCAN/LEF1/SMAD3/NOTCH1/MYOC/IL6ST/TOB1/ADAR/ALPL/ACVR1/FBXO5/FGF9/WWTR1/IL6/BCAP29/PRKD1/CEBPA/CAT/PTH1R/ATRAID	43
BP	GO:0072330	monocarboxylic acid biosynthetic process	60/2112	343/18670	0.0003912	0.003908	0.002823	IGF1/IDO1/LTC4S/ZBTB20/PLP1/AKR1C3/ACADVL/CD74/ACOX2/SLC2A6/CBFA2T3/NUP93/HDAC4/HK3/ALDOC/DCN/BGN/SLC1A3/TPR/CSPG4/ERLIN1/FA2H/PER2/HPGDS/NUP160/ACACB/HTR2A/VCAN/GPX4/HSD17B12/LIPG/IFNG/ARNT/KMO/RGN/ADIPOQ/ERLIN2/FABP5/PDK4/PTGS1/ELOVL4/DHRS9/NR1H3/OSBPL1A/SLC27A5/CYP46A1/ACADL/OSBPL9/NUP88/ELOVL2/ACSM5/ACSM3/LIPC/NUP50/TP53/PRKAB1/IL1B/EPHX2/ALOX5/ELOVL5	60
BP	GO:0002523	leukocyte migration involved in inflammatory response	7/2112	14/18670	0.0003912	0.003908	0.002823	SLAMF8/S100A9/JAM3/ITGB2/ADAM8/SELE/PTN	7
BP	GO:0045591	positive regulation of regulatory T cell differentiation	7/2112	14/18670	0.0003912	0.003908	0.002823	LILRB2/HLA-G/LGALS9/SOCS1/BTN2A2/LILRB4/IFNG	7
BP	GO:0046629	gamma-delta T cell activation	7/2112	14/18670	0.0003912	0.003908	0.002823	PTPRC/NOD2/MICB/GPR18/NCKAP1L/SYK/LILRB1	7
BP	GO:0050862	positive regulation of T cell receptor signaling pathway	7/2112	14/18670	0.0003912	0.003908	0.002823	LCK/TRAT1/CCR7/PRKD2/ADA/CD226/CD81	7
BP	GO:0098727	maintenance of cell number	33/2112	159/18670	0.000393	0.003919	0.002831	SFRP1/IGF1/ASPM/SOX9/SKI/BMPR1A/SIX2/ZNF358/YAP1/GATA2/FGF2/EZH2/SOX2/PTN/CDH2/TP63/MCPH1/PBX1/ZNF322/FOXO1/FZD7/NOTCH1/MTF2/POLR2L/SPI1/NIPBL/PAF1/ZHX2/FOXO3/DDX6/MED14/ZFP36L2/SS18	33
BP	GO:0007596	blood coagulation	59/2112	336/18670	0.0003938	0.00392	0.002833	SERPINA1/LCK/PIK3R1/IRF1/PRKCH/PRKCQ/SERPINA5/SH2B2/PRKCB/AXL/LCP2/HBB/ZFPM2/JAK2/CD36/CD40/COMP/IRF2/GATA2/PDPN/PTPN6/PROS1/F5/PROCR/PLCG2/WAS/PLEK/VKORC1/CD40LG/PLAT/DOCK1/RAB27A/PTPN11/VAV1/CD9/HBD/DGKA/PIK3CA/MICAL1/SYK/AKAP1/TEC/STXBP1/HSPB1/IL6/FZD6/PRKG1/ENTPD1/PLSCR1/CAPZA1/FBLN1/MYL9/TFPI/LYN/SH2B3/MERTK/GP1BA/IFNA1/VAV3	59
BP	GO:0030890	positive regulation of B cell proliferation	13/2112	41/18670	0.0003964	0.003937	0.002845	PTPRC/GPR183/SASH3/CD74/CD40/TFRC/ADA/NCKAP1L/TNFRSF4/CD38/CD320/CD81/VAV3	13
BP	GO:0000302	response to reactive oxygen species	44/2112	232/18670	0.0003967	0.003937	0.002845	PLEKHA1/TNFAIP3/GCH1/NQO1/STAT1/CCL19/AKR1C3/CCR7/AXL/SIGMAR1/HBB/CRYAB/CD36/PDGFD/EGFR/FBLN5/ADA/SPHK1/CDK1/BAK1/HGF/CCNA2/EZH2/SOD1/MAPK13/PPP2CB/FOXO1/NET1/HYAL1/ECT2/RGN/SLC8A1/FOSL1/PINK1/BTK/IL6/FER/HP/FOXO3/SESN1/PKD2/CFLAR/CAT/NCF1	44
BP	GO:0031098	stress-activated protein kinase signaling cascade	56/2112	315/18670	0.0003987	0.00395	0.002854	SFRP1/STK10/SLAMF1/RASGRP1/CCL19/TPD52L1/SEMA3A/CCR7/SKP1/MAP3K11/NEK1/LGALS9/NOD2/CRYAB/TNIP2/MAP3K8/RIPK2/AKR1B1/EGFR/SPHK1/MAP4K1/CCL21/HGF/CD27/EPHB1/CD40LG/MAPK13/ARL6IP5/CCDC88C/NFKB1/FZD4/FOXO1/FZD7/MFHAS1/ZMYND11/MAP3K2/LEP/ZFP36L1/PTGER4/PAK1/DACT1/SYK/PHLPP1/IKBKG/PINK1/MAPKAPK2/PTPN22/IL1RN/LYN/NOD1/HIPK2/NCF1/PRMT1/PBK/TLR6/IL1B	56
BP	GO:1903901	negative regulation of viral life cycle	21/2112	85/18670	0.0004027	0.003977	0.002874	CCL5/FCN1/SLPI/APOBEC3G/OAS1/ISG20/SRPK1/OASL/FAM111A/TRIM21/MPHOSPH8/OAS3/IFIT5/PLSCR1/TRIM26/MX1/ZC3HAV1/ISG15/GSN/PTX3/PML	21
BP	GO:2001057	reactive nitrogen species metabolic process	21/2112	85/18670	0.0004027	0.003977	0.002874	CLU/GCH1/NQO1/TLR2/HBB/ITGB2/ICAM1/JAK2/CD36/DDAH2/CLEC7A/CX3CR1/SMAD3/IFNG/RGN/HSP90AB1/GLA/PKD2/TLR6/IL1B/PTX3	21
BP	GO:0045638	negative regulation of myeloid cell differentiation	22/2112	91/18670	0.0004107	0.004044	0.002922	PIK3R1/SFRP1/ZBTB16/INHBA/MEIS1/PTPN2/LILRB3/GATA2/MEIS2/GPR171/LILRB4/NFKBIA/ZFP36L1/ADIPOQ/PAF1/INPP5D/LYN/FSTL3/PRMT1/TOB2/HOXA5/LILRB1	22
BP	GO:0045639	positive regulation of myeloid cell differentiation	22/2112	91/18670	0.0004107	0.004044	0.002922	KITLG/STAT1/INHBA/CD74/HCLS1/GATA2/EVI2B/CCR1/NCKAP1L/LEF1/CA2/ZFP36L1/IFNG/ARNT/TRIM58/INPP5D/TESC/FOXO3/RB1/PRMT1/ISG15/HOXA5	22
BP	GO:0032652	regulation of interleukin-1 production	24/2112	103/18670	0.0004129	0.004049	0.002926	AIM2/TNFAIP3/IGF1/TLR8/CCL19/CCR7/LGALS9/NOD2/MALT1/JAK2/RIPK2/SPHK1/CLEC7A/CX3CR1/CASP1/SMAD3/MNDA/IFNG/SERPINB1/HSPB1/NOD1/PANX1/PML/NLRP3	24
BP	GO:1902106	negative regulation of leukocyte differentiation	24/2112	103/18670	0.0004129	0.004049	0.002926	PIK3R1/SFRP1/CTLA4/BMP4/IRF1/RUNX3/GLI3/INHBA/CD74/PTPN2/IL4R/HLA-G/LILRB3/SOCS1/GATA2/ERBB2/TBX21/LILRB4/ADIPOQ/INPP5D/LYN/FSTL3/TOB2/LILRB1	24
BP	GO:0032231	regulation of actin filament bundle assembly	23/2112	97/18670	0.0004139	0.004049	0.002926	PIK3R1/SFRP1/LIMCH1/LPAR1/PFN2/ITGB1BP1/DLC1/TAC1/WAS/PLEK/NOX4/ARHGEF10/SMAD3/CORO2B/GPR65/MYOC/PPM1F/PTGER4/PAK1/TGFB3/WASF2/S1PR1/PFN1	23
BP	GO:0120162	positive regulation of cold-induced thermogenesis	23/2112	97/18670	0.0004139	0.004049	0.002926	CCR2/CXCR4/IRF4/IL4R/DIO2/JAK2/CD36/PLAC8/TRPV2/PER2/LEP/ADIPOQ/SYK/FABP5/G0S2/UCP2/IL18/FABP4/ACADL/HADH/PRKAB1/YBX2/THRA	23
BP	GO:1901988	negative regulation of cell cycle phase transition	49/2112	267/18670	0.000426	0.004161	0.003006	PSMB9/CDKN2C/PSMB8/TFDP2/PSMB10/DTL/BUB1/SKP1/NDC80/KANK2/MAD2L1/PLK1/PSME1/CDC14B/BTN2A2/BLM/E2F8/FHL1/TPR/CDK1/ZNF207/EZH2/BUB1B/PLK2/DONSON/ZFP36L1/CCNB1/DACT1/CCND1/FBXO5/CENPF/TTK/MIIP/AURKB/RB1/CDC20/FBXL7/SYF2/PKD2/NAE1/ZFP36L2/PRMT1/PCBP4/TRIP13/TP53/CCL2/AURKA/TOPBP1/PML	49
BP	GO:0050710	negative regulation of cytokine secretion	19/2112	74/18670	0.0004452	0.004338	0.003134	TNFAIP3/GBP1/IL27RA/TLR8/CD200/ANGPT1/BTN2A2/SRGN/PTGER4/SERPINB1/TNFRSF4/PTPN22/ANXA4/PPP1R11/LRRC32/TLR6/PML/LILRB1/NLRP3	19
BP	GO:0048608	reproductive structure development	72/2112	431/18670	0.0004455	0.004338	0.003134	KITLG/PLEKHA1/SFRP1/BMP4/LRP6/CDKN1C/ASPM/HOXA10/ADAM19/SERPINA5/SOX9/GLI3/FOXC1/SEMA3A/INHBA/AKR1C3/RHOBTB3/AXL/TNFSF10/HTRA1/AR/SULF1/ZFPM2/SGPL1/ICAM1/GATA2/EGFR/ADA/E2F8/DCN/BPTF/SPINT2/TCF7/BAK1/PTN/TP63/SOD1/BCL2L2/FZD4/CTSB/LEF1/PTPN11/ATRX/RBP4/IRX5/NOTCH1/LEP/ZFP36L1/ARNT/HEY2/HSP90AB1/CCND1/FOSL1/FGF9/KRT19/NIPBL/REC8/LDOC1/FOXO3/ANG/CEBPA/FSTL3/HEY1/PKD2/MERTK/REN/ERCC1/HOXA11/CCNF/EAF2/NRIP1/PTX3	72
BP	GO:0001666	response to hypoxia	62/2112	359/18670	0.0004479	0.004354	0.003146	PSMB9/NDNF/SFRP1/PSMB8/PENK/CXCR4/PSMB10/TLR2/CBFA2T3/PAM/ICAM1/ADAM8/CRYAB/PSME1/CPEB1/ADA/TGFBR3/CREBBP/KCNK2/CCNA2/PCK1/PTN/PLAT/NOX4/PMAIP1/ATP1B1/BACH1/SMAD3/ANGPTL4/FAM162A/NOTCH1/LEP/HIGD1A/ZFP36L1/ARNT/CCNB1/PDLIM1/MECP2/SLC8A1/PAK1/ADIPOQ/TGFB3/PINK1/APAF1/CD38/CUL2/FOXO3/LMNA/UCP2/CYBA/VEGFB/ANG/APOLD1/HIPK2/CFLAR/CAT/ALAD/TP53/BNIP3L/HP1BP3/PML/TXN2	62
BP	GO:0000086	G2/M transition of mitotic cell cycle	46/2112	247/18670	0.0004512	0.004372	0.003159	PSMB9/PSMB8/PSMB10/DTL/TPD52L1/CETN2/SKP1/CCNB2/HMMR/PLK1/TPX2/BORA/TUBA4A/PSME1/MELK/BLM/CDC25B/FHL1/SMARCD3/CDK1/CCNA2/CEP135/TUBB4A/PBX1/NEK2/BACH1/CDK14/BRD4/DONSON/CDC7/CCNB1/MECP2/CCND1/FBXO5/CNTRL/CENPF/MIIP/AURKB/ENSA/CEP63/FBXL7/SYF2/NAE1/KHDRBS1/AURKA/TOPBP1	46
BP	GO:0097237	cellular response to toxic substance	46/2112	247/18670	0.0004512	0.004372	0.003159	PLEKHA1/TNFAIP3/S100A9/GCH1/NQO1/LTC4S/GSTM3/AXL/SIGMAR1/HBB/CD36/PDGFD/FBLN5/ESD/SPHK1/ABTB2/CDK1/HGF/ADIRF/EZH2/SOD1/MAPK13/NFKB1/GPX3/IPCEF1/FOXO1/NET1/GPX4/ECT2/HBD/TIMELESS/RGN/CCL7/PRDX6/SPI1/PINK1/PTGS1/IL6/ADH5/HP/FOXO3/SESN1/KDR/GSTO1/CAT/GSTM2	46
BP	GO:0050709	negative regulation of protein secretion	30/2112	141/18670	0.0004565	0.004417	0.003191	SFRP1/TNFAIP3/GBP1/IL27RA/TLR8/RHBDF2/PPP3CA/CD200/ANGPT1/BTN2A2/SRGN/KLF7/IDH2/RHBDF1/PTPN11/PTGER4/SERPINB1/TNFRSF4/PTPN22/ANXA4/NR1H3/PPP1R11/HADH/LRRC32/TLR6/IL1B/PML/RAB11FIP1/LILRB1/NLRP3	30
BP	GO:0002825	regulation of T-helper 1 type immune response	10/2112	27/18670	0.0004596	0.00444	0.003208	XCL1/CCR2/IL27RA/CCL19/IL4R/RIPK2/CD80/IL18/IL1R1/IL1B	10
BP	GO:0019216	regulation of lipid metabolic process	69/2112	410/18670	0.0004697	0.00453	0.003273	PIK3R1/BCL11B/ZBTB20/SERPINA3/CCL19/AKR1C3/ACADVL/CCR7/ABCG1/NFE2L1/CD74/NOD2/PMVK/CD36/HTR2B/SOCS1/FGR/CISH/FGF2/CREBBP/SPHK1/CCL21/SMARCD3/SIK1/ERLIN1/SP1/SOCS2/SOD1/ACACB/NFKB1/HTR2A/CD19/SC5D/ANGPTL4/ALAS1/LEP/AGTR1/IFNG/RGN/SOCS6/NFYA/FLT3/ADIPOQ/ERLIN2/FABP5/GFI1/PDK4/SORBS1/PIK3R3/G0S2/NR1H3/FPR2/RB1/PRKD1/MBTPS2/ABHD6/LYN/ACADL/PDE3B/CD81/DKK3/CHD9/MTMR2/TBL1X/VAV3/IL1B/EPHX2/ELOVL5/THRA	69
BP	GO:0001894	tissue homeostasis	43/2112	227/18670	0.000471	0.004536	0.003277	TNFAIP3/CCR2/TNFRSF11B/CORO1A/CSK/RAC2/SERPINA3/SOX9/LTBP3/FOXC1/SASH3/TCIRG1/NOD2/ADAM8/LYZ/YAP1/GATA2/AKR1B1/TFRC/EGFR/BARD1/NOX4/SOD1/PTPN11/CA2/RBP4/NOTCH1/SYK/BBS1/PDK4/HSPB1/WWTR1/AKT3/IL6/CD38/INPP5D/RCN3/RB1/SNX10/S1PR1/PTH1R/NPHP4/CTSH	43
BP	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	21/2112	86/18670	0.0004769	0.004571	0.003303	LCK/S100A9/BID/TNFSF10/JAK2/DLC1/DAP/CASP10/BAK1/CASP1/PMAIP1/SMAD3/FAM162A/VCP/CASP5/APAF1/NOD1/CASP4/PML/CTSH/NLRP3	21
BP	GO:0030101	natural killer cell activation	21/2112	86/18670	0.0004769	0.004571	0.003303	PTPRC/CD2/CORO1A/RASGRP1/IL21R/HLA-F/IL15/ELF4/AXL/ITGB2/MICB/HLA-E/PIK3CD/RAB27A/TOX/LEP/PTPN22/IL18/SLAMF7/MERTK/IFNA1	21
BP	GO:0070542	response to fatty acid	21/2112	86/18670	0.0004769	0.004571	0.003303	PID1/SFRP1/CCL19/AKR1C3/CCR7/TLR2/CD36/TGFBR3/CCL21/ID3/CCNB1/OR51E2/PTGFR/PTGER4/SMARCD1/ADIPOQ/P2RY6/PDK4/CAT/ALAD/P2RY4	21
BP	GO:1905475	regulation of protein localization to membrane	37/2112	187/18670	0.0004833	0.004626	0.003342	PID1/PIK3R1/EPHA3/GBP1/TFDP2/PRKCH/GPC5/CSK/GZMB/BID/ITGB1BP1/ITGB2/AR/EGFR/DAG1/ERBB2/PTN/CDH2/TP63/PMAIP1/GDI1/RHOG/IFNG/PAK1/MYO1C/STX4/GPC4/SORBS1/ADAM10/CLIP3/TP53BP2/CD81/VTI1B/RAB11FIP2/TP53/SPTBN1/GSN	37
BP	GO:0051668	localization within membrane	31/2112	148/18670	0.0004922	0.004704	0.003399	PTPRC/CD2/ITGB7/RFTN1/ITGA4/RAB8A/GLRB/ITGB1BP1/ITGB2/USP46/DNM1/DAG1/ETV5/ITGAL/SEC31A/MAGI2/NLGN1/CLSTN1/PTN/CDH2/ATP1B1/ADAM22/DOCK2/GPC4/LGI1/ADAM10/DVL1/CD81/SEC23B/GSN/CEP112	31
BP	GO:0016049	cell growth	79/2112	484/18670	0.0005006	0.004777	0.003451	ENPP1/CDKN2C/SFRP1/S100A9/IGFBP5/IGF1/SEMA4A/PLCE1/CXCR4/NDN/PRKCQ/SOX9/SIPA1/ITGA4/SEMA4D/SEMA3A/INHBA/PPP2CA/CHPT1/SPOCK1/AUTS2/KAZALD1/CRLF3/CRYAB/NDRG3/COBL/RPS6KA1/CISH/EGFR/FBLN5/HBEGF/SPHK1/FHL1/FGF13/TRPV2/ERBB2/SORBS2/SOCS2/CLSTN1/TSPYL2/PDLIM5/NDUFA13/RYK/PTPRS/LEF1/SEMA3F/NET1/HYAL1/CYFIP2/EFNA5/SMAD3/SMARCA2/GDI1/AGTR1/SYT17/HSP90AB1/PAK1/CTTN/AKAP13/MAP1B/LGI1/ARHGAP4/CD38/MEGF8/BCL11A/DPYSL2/SEMA4F/RB1/CYBA/SEMA3E/ADAM10/DVL1/SEMA6B/TP53/DCBLD2/EAF2/AURKA/PML/DCLK1	79
BP	GO:0070227	lymphocyte apoptotic process	18/2112	69/18670	0.0005066	0.004814	0.003478	CCL5/BMP4/IDO1/PRKCQ/IL7R/GLI3/CD74/CD3G/LGALS9/ADAM8/ADA/BAK1/CD27/BTK/AURKB/LYN/IL2RA/TP53	18
BP	GO:0045589	regulation of regulatory T cell differentiation	11/2112	32/18670	0.0005069	0.004814	0.003478	CTLA4/IRF1/LILRB2/HLA-G/LGALS9/SOCS1/BTN2A2/CR1/LILRB4/IFNG/IL2RA	11
BP	GO:0071353	cellular response to interleukin-4	11/2112	32/18670	0.0005069	0.004814	0.003478	IL2RG/XCL1/CORO1A/PTPN2/IL4R/TCF7/LEF1/MCM2/HSP90AB1/ALAD/PML	11
BP	GO:0097028	dendritic cell differentiation	13/2112	42/18670	0.0005153	0.004887	0.003531	RELB/LILRB2/CCL19/BATF/CCR7/IRF4/AXL/HLA-G/LGALS9/FLT3/SPI1/LYN/LILRB1	13
BP	GO:0038083	peptidyl-tyrosine autophosphorylation	12/2112	37/18670	0.0005226	0.004949	0.003576	ITK/LCK/FGR/EGFR/TXK/TEC/FRK/BTK/LYN/KDR/SLA/HCK	12
BP	GO:0048638	regulation of developmental growth	60/2112	347/18670	0.0005315	0.005024	0.00363	FTO/SFRP1/GDF5/BMP4/IGF1/SEMA4A/CXCR4/NPY1R/SEMA4D/PIM1/FOXC1/SEMA3A/MEIS1/SASH3/AR/ZFPM2/SGPL1/SIX1/BMPR1A/PLAC8/YAP1/FGF2/TGFBR3/FGF13/TRPV2/GHR/CDK1/KCNK2/SOCS2/AFG3L2/SOD1/ACACB/RYK/PTPRS/SEMA3F/EFNA5/RBP4/NOTCH1/GDI1/LEP/CCNB1/PIK3CA/PRL/HEY2/SYT17/PAK1/FGF9/CTTN/NIPBL/MAP1B/ARHGAP4/MEGF8/DUSP6/BCL11A/DPYSL2/SEMA4F/JARID2/SEMA3E/DIO3/SEMA6B	60
BP	GO:0150076	neuroinflammatory response	19/2112	75/18670	0.0005339	0.00504	0.003641	PTPRC/IGF1/CLU/TLR8/TNFRSF1B/CST7/TLR2/CD200/ITGB2/JAK2/CTSC/EGFR/SPHK1/IFNG/IL6/FPR2/IL18/TLR6/IL1B	19
BP	GO:0032147	activation of protein kinase activity	58/2112	333/18670	0.0005413	0.005095	0.003681	CCL5/PTPRC/STK10/BMP4/IGF1/PLCE1/CXCR4/CCL19/DUSP5/LPAR1/EMP2/ANGPT1/CD74/ITGB1BP1/MAP3K11/NEK1/NOD2/MALT1/JAK2/TPX2/BORA/SOCS1/MAP3K8/RIPK2/EGFR/GPRC5A/FGF2/MAP4K1/FGF13/CSPG4/GHR/CDK1/HGF/CD40LG/NCKAP1L/SOD1/TOM1L1/EFNA5/PTPN11/ECT2/MAP3K2/LEP/FPR1/PIK3CA/PAK1/SYK/IKBKG/TGFB3/PINK1/MAPKAPK2/DUSP6/IL18/ANG/NOD1/SHC2/CD81/TLR6/IL1B	58
BP	GO:0071560	cellular response to transforming growth factor beta stimulus	46/2112	249/18670	0.0005413	0.005095	0.003681	XCL1/SFRP1/GDF5/FMOD/CDKN1C/PENK/SOX9/LTBP3/SKI/PARD3/ARHGEF18/SOX5/HTRA1/FERMT2/CILP/LTBP2/BMPR1A/ADAMTSL2/PDGFD/TWSG1/TGFBR3/CREBBP/GLG1/CX3CR1/CHST11/NOX4/PMEPA1/SMAD3/LDLRAD4/ZFP36L1/HSP90AB1/ACVR1/PARP1/TGFB3/APAF1/NLK/FERMT1/HIPK2/DKK3/FUT8/CFLAR/ZFP36L2/LRRC32/TP53/CDH5/PML	46
BP	GO:0048732	gland development	72/2112	434/18670	0.0005453	0.005113	0.003694	SFRP1/TNFAIP3/BMP4/BCL11B/IGFBP5/LRP6/CDKN1C/CDO1/SERPINA5/SOX9/GLI3/FOXC1/SEMA3A/OAS2/FGF7/CCNB2/AR/SULF1/PAM/SIX1/BMPR1A/WLS/JAK2/COBL/TWSG1/GATA2/RPS6KA1/EGFR/ADA/DAG1/TGFBR3/ETV5/E2F8/NFIB/HGF/FA2H/EZH2/SOX2/ACAT1/SOCS2/PCK1/PTN/LRP5/TP63/SOD1/PITX1/PBX1/IGSF3/LEF1/SMAD3/NOTCH1/SEC63/RGN/PIK3CA/PRL/CCND1/HFE/TGFB3/TYMS/JARID2/CEBPA/FSTL3/PKD2/DKK3/CFLAR/TGM2/EAF2/AURKA/LIMS2/HOXA5/PML/THRA	72
BP	GO:0061458	reproductive system development	72/2112	434/18670	0.0005453	0.005113	0.003694	KITLG/PLEKHA1/SFRP1/BMP4/LRP6/CDKN1C/ASPM/HOXA10/ADAM19/SERPINA5/SOX9/GLI3/FOXC1/SEMA3A/INHBA/AKR1C3/RHOBTB3/AXL/TNFSF10/HTRA1/AR/SULF1/ZFPM2/SGPL1/ICAM1/GATA2/EGFR/ADA/E2F8/DCN/BPTF/SPINT2/TCF7/BAK1/PTN/TP63/SOD1/BCL2L2/FZD4/CTSB/LEF1/PTPN11/ATRX/RBP4/IRX5/NOTCH1/LEP/ZFP36L1/ARNT/HEY2/HSP90AB1/CCND1/FOSL1/FGF9/KRT19/NIPBL/REC8/LDOC1/FOXO3/ANG/CEBPA/FSTL3/HEY1/PKD2/MERTK/REN/ERCC1/HOXA11/CCNF/EAF2/NRIP1/PTX3	72
BP	GO:1904019	epithelial cell apoptotic process	25/2112	111/18670	0.0005458	0.005113	0.003694	NDNF/TNFAIP3/ITGA4/AKR1C3/ANGPT1/BID/HLA-G/ICAM1/TNIP2/JAK2/CD40/SCG2/GATA2/CD160/TCF7L2/CD40LG/ANGPTL4/ZFP36L1/IL6/FOXO3/RB1/KDR/CFLAR/CCL2/GSN	25
BP	GO:0032388	positive regulation of intracellular transport	41/2112	215/18670	0.0005473	0.005119	0.003699	PIK3R1/ZIC1/RAC2/GLI3/HCLS1/ITGB1BP1/ITGB2/IL4R/GATA2/FGR/CPSF6/TPR/ERBB2/TCF7L2/NLGN1/ZPR1/SMAD3/EDEM1/FEZ1/ECT2/LEP/IFNG/STX18/PAK1/MYO1C/SYK/ZFAND1/VAMP2/STXBP1/PINK1/GAB2/HSPA1L/KIF20B/CD81/EDEM2/PRR5L/MTMR2/TP53/KHDRBS1/IL1B/XPO4	41
BP	GO:0043547	positive regulation of GTPase activity	68/2112	405/18670	0.0005489	0.005127	0.003704	CCL5/CXCL13/XCL1/SFRP1/RASGRP1/ARHGDIB/FAM13A/ARHGAP25/CCL19/SIPA1/SEMA4D/TBC1D16/DOCK10/CCL13/RASGRP3/CCR7/TBC1D5/MAPRE2/ICAM1/RABGAP1/ACAP1/CD40/HTR2B/TBC1D9/DLC1/STARD8/DENND1A/CCL21/ARHGAP17/ERBB2/TBC1D8B/AGAP1/ARHGAP22/EZH2/ASAP2/DOCK1/NCKAP1L/TBC1D1/ARHGEF10/CCL18/RABGAP1L/GMIP/ARHGEF12/NET1/DOCK2/VAV1/GPR65/RASA2/CHN1/RACGAP1/ECT2/GDI1/RHOG/RGN/CCL7/DEPDC1/ARHGAP4/RALBP1/RGS1/CCL17/S1PR1/RAB11FIP2/NUP50/CCL2/SEC23B/CCL23/VAV3/ARHGAP12	68
BP	GO:0072243	metanephric nephron epithelium development	9/2112	23/18670	0.0005529	0.005157	0.003726	STAT1/SOX9/YAP1/ACAT1/ADIPOQ/WWTR1/FAT4/PKD2/POU3F3	9
BP	GO:0045669	positive regulation of osteoblast differentiation	17/2112	64/18670	0.0005729	0.005335	0.003855	NELL1/BMP4/IGF1/DDR2/ZHX3/GLI3/BMPR1A/HGF/LRP5/TP63/IL6ST/ACVR1/FBXO5/IL6/PRKD1/CEBPA/ATRAID	17
BP	GO:0050702	interleukin-1 beta secretion	15/2112	53/18670	0.0005752	0.00534	0.003858	AIM2/TNFAIP3/TLR8/CCL19/CCR7/LGALS9/NOD2/CD36/RIPK2/CASP1/SERPINB1/PANX1/TLR6/PML/NLRP3	15
BP	GO:0070228	regulation of lymphocyte apoptotic process	15/2112	53/18670	0.0005752	0.00534	0.003858	CCL5/BMP4/IDO1/PRKCQ/IL7R/CD74/CD3G/LGALS9/ADAM8/ADA/CD27/BTK/AURKB/LYN/TP53	15
BP	GO:0002604	regulation of dendritic cell antigen processing and presentation	6/2112	11/18670	0.0005799	0.00536	0.003872	CCL19/CCR7/CD74/NOD2/CCL21/NOD1	6
BP	GO:0046950	cellular ketone body metabolic process	6/2112	11/18670	0.0005799	0.00536	0.003872	OXCT1/ACSS3/ACAT1/BDH2/BDH1/SLC27A5	6
BP	GO:0070106	interleukin-27-mediated signaling pathway	6/2112	11/18670	0.0005799	0.00536	0.003872	CRLF1/IL27RA/STAT1/JAK2/IL6ST/TYK2	6
BP	GO:0006606	protein import into nucleus	30/2112	143/18670	0.000585	0.005399	0.003901	PIK3R1/BMP4/ZIC1/GLI3/PPP3CA/ANGPT1/HCLS1/CD36/NUP93/SIX2/TPR/NFKBIA/ZPR1/SMAD3/ARNTL/ECT2/LEP/IFNG/SYK/FGF9/IPO7/KPNA2/LMNA/FERMT1/NUP88/NUP50/TP53/HEATR3/MMP12/PML	30
BP	GO:0051100	negative regulation of binding	34/2112	169/18670	0.0005872	0.005411	0.00391	GZMA/ITGA4/SRI/SLPI/PPP3CA/ITGB1BP1/JAK2/GOLGA2/BAG2/PLN/ID3/PER2/NFKBIA/PTPRF/NEK2/LRPAP1/LEF1/GTF2F1/PPP1CA/HEY2/ADIPOQ/DACT1/PEX19/HFE/DDIT3/AURKB/RSF1/CRTAC1/HEY1/DVL1/IFIT2/PIM2/CCL23/AURKA	34
BP	GO:0051216	cartilage development	40/2112	209/18670	0.0005894	0.005423	0.003918	GDF5/BMP4/LRP6/RUNX3/SCARA3/WNT5B/MGP/TRPS1/PTHLH/FGF18/SOX9/ZBTB16/GLI3/LTBP3/SOX5/SULF1/COCH/BMPR1A/SIX2/COMP/SHOX2/FGF2/NFIB/COL14A1/CREB3L2/GLG1/HOXC4/CHST11/LUM/PITX1/EFEMP1/HYAL1/SMAD3/LEP/FGF9/TYMS/PTH1R/HOXA11/HOXA5/THRA	40
BP	GO:0030111	regulation of Wnt signaling pathway	62/2112	363/18670	0.000602	0.005531	0.003996	PSMB9/SFRP1/TNFAIP3/PSMB8/LRP6/GPC5/WNT5B/ASPM/RBMS3/PSMB10/SOX9/GLI3/TSKU/SKI/PPP2CA/TLR2/CBY1/IGFBP6/SULF1/WLS/ZBED2/YAP1/PSME1/EGFR/UBE2B/RECK/TCF7L2/SOX2/CDH2/PLEKHA4/NFKB1/LEF1/FOXO1/CDK14/SMAD3/DIXDC1/FZD7/DAAM2/NOTCH1/ARNTL/VCP/KANK1/PPP1CA/TCF7L1/DACT1/FGF9/WWTR1/FZD6/DDIT3/NLK/FOXO3/FERMT1/IGFBP2/RNF146/DVL1/DKK3/NLE1/WIF1/FRAT1/NPHP4/TBL1X/SPIN1	62
BP	GO:0032869	cellular response to insulin stimulus	41/2112	216/18670	0.0006032	0.005533	0.003998	ENPP1/PID1/PIK3R1/STAT1/PTPRE/PRKCQ/SH2B2/NUCKS1/RAB8A/PRKCB/PTPN2/TCIRG1/SOCS1/CISH/CPEB1/SP1/SOCS2/PCK1/ZNF106/FOXO1/PTPN11/KL/KANK1/LEP/ZFP36L1/PIK3CA/PAK1/MYO1C/ADIPOQ/PDK4/SORBS1/PARP1/VAMP2/PIK3R3/FER/FOXO3/PDE3B/CFLAR/IRS4/ATP6V1B2/IL1B	41
BP	GO:0050817	coagulation	59/2112	342/18670	0.0006242	0.005715	0.004129	SERPINA1/LCK/PIK3R1/IRF1/PRKCH/PRKCQ/SERPINA5/SH2B2/PRKCB/AXL/LCP2/HBB/ZFPM2/JAK2/CD36/CD40/COMP/IRF2/GATA2/PDPN/PTPN6/PROS1/F5/PROCR/PLCG2/WAS/PLEK/VKORC1/CD40LG/PLAT/DOCK1/RAB27A/PTPN11/VAV1/CD9/HBD/DGKA/PIK3CA/MICAL1/SYK/AKAP1/TEC/STXBP1/HSPB1/IL6/FZD6/PRKG1/ENTPD1/PLSCR1/CAPZA1/FBLN1/MYL9/TFPI/LYN/SH2B3/MERTK/GP1BA/IFNA1/VAV3	59
BP	GO:0045931	positive regulation of mitotic cell cycle	33/2112	163/18670	0.0006248	0.005715	0.004129	IGF1/BTC/DTL/CCND2/NUSAP1/UBE2C/NDC80/MAD2L1/MEIS2/EGFR/CDC45/SPHK1/CDC25B/TPR/SMARCD3/CDK1/DLGAP5/LRP5/PBX1/HYAL1/PTPN11/BRD4/CDC7/CCNB1/MECP2/CCND1/FBXO5/NIPBL/RB1/CUL4B/KIF20B/AURKA/IL1B	33
BP	GO:0060419	heart growth	25/2112	112/18670	0.0006284	0.00574	0.004147	IGF1/PIM1/FOXC1/MEIS1/ZFPM2/BMPR1A/YAP1/FGF2/TGFBR3/CDK1/KCNK2/SORBS2/PDLIM5/ACACB/RBP4/NOTCH1/CCNB1/HEY2/PAK1/FGF9/AKAP13/DUSP6/JARID2/TENM4/S1PR1	25
BP	GO:0002710	negative regulation of T cell mediated immunity	8/2112	19/18670	0.0006324	0.005759	0.004161	XCL1/PTPRC/HLA-F/IL7R/HLA-G/TBX21/HFE/LILRB1	8
BP	GO:0045076	regulation of interleukin-2 biosynthetic process	8/2112	19/18670	0.0006324	0.005759	0.004161	CD3E/PTPRC/PRKCQ/IRF4/CLEC7A/CD86/CD80/IL1B	8
BP	GO:0051052	regulation of DNA metabolic process	71/2112	429/18670	0.0006356	0.005779	0.004175	GZMA/PTPRC/IL27RA/EYA4/PRKCQ/IL7R/NUCKS1/PPP2CA/ZNF365/EYA2/CD40/PRKD2/ANXA3/TTF1/TFRC/EGFR/UBE2B/FGF2/BLM/KMT2A/E2F8/ZBTB38/WAS/CDK1/HGF/KCNK2/TBX21/CCNA2/STAG2/TSPYL2/ID3/NOX4/NEK7/RFC3/PPP4C/NEK2/DNMT1/ATRX/TNFAIP1/DONSON/TIMELESS/CDC7/RGN/PIK3CA/MECP2/MPHOSPH8/TERF1/HSP90AB1/ADIPOQ/PARP4/RLF/DBF4/FBXO5/PARP1/SPI1/APAF1/IL6/KPNA2/AURKB/RAD51AP1/ERCC1/THOC1/SETMAR/SMCHD1/TP53/USP7/PARM1/PARN/ACTR2/DNAJC2/PML	71
BP	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway	10/2112	28/18670	0.000643	0.005838	0.004218	GBP1/PVRIG/LPXN/PTPN2/BTN2A2/PTPN6/CD160/LILRB4/PTPN22/UBASH3A	10
BP	GO:0045017	glycerolipid biosynthetic process	46/2112	251/18670	0.0006472	0.005868	0.00424	PLA2G2D/PLEKHA1/CPNE3/PIK3R1/PIGK/GK/PLCE1/CHPT1/PIP4K2B/HTR2B/FGF2/SH3YL1/DPM3/PLCG2/SIK1/GPAA1/PLD1/MTMR14/ETNK1/PCK1/PLA2G12A/PIK3CD/PIGH/PLEKHA4/HTR2A/PTPN13/RGN/DGKA/PIK3CA/PIGP/FABP5/PLEKHA2/PIK3R3/INPP5D/PTDSS1/PLSCR1/NR1H3/PIP4K2A/FPR2/STARD7/ANG/PIGT/PIGF/MTMR2/RAB14/GPD1L	46
BP	GO:0009612	response to mechanical stimulus	40/2112	210/18670	0.0006502	0.005886	0.004253	GDF5/IRF1/TLR8/STAT1/CXCR4/SOX9/MYD88/HDAC4/CD40/CXCL10/MEIS2/EGFR/DAG1/DCN/SLC1A3/BAK1/KCNK2/NFKBIA/PTN/TLR5/KCNJ2/NFKB1/CASP1/HTR2A/PTPN11/MAP3K2/CASP5/PIEZO2/PSPH/CCNB1/ATP1A2/SLC8A1/PTGER4/FOSL1/BACE1/MAP1B/CYBA/IGFBP2/PKD2/IL1B	40
BP	GO:0051279	regulation of release of sequestered calcium ion into cytosol	20/2112	82/18670	0.0006539	0.005911	0.004271	CXCL9/XCL1/CORO1A/SRI/ANK2/CXCL10/PTPN6/PLN/TRPC1/CD19/ATP1A2/CXCL11/SLC8A1/P2RY6/APLNR/CYBA/LYN/PKD2/GSTO1/GSTM2	20
BP	GO:0032868	response to insulin	49/2112	272/18670	0.0006566	0.005916	0.004275	ENPP1/PID1/PIK3R1/STAT1/PTPRE/PRKCQ/SH2B2/NUCKS1/RAB8A/PRKCB/TLR2/PTPN2/TNFSF10/TCIRG1/ICAM1/SOCS1/CISH/CPEB1/SP1/SOCS2/PLN/PCK1/ZNF106/FOXO1/PTPN11/KL/KANK1/LEP/ZFP36L1/PIK3CA/PAK1/MYO1C/ADIPOQ/PDK4/SORBS1/PARP1/VAMP2/PIK3R3/FER/FOXO3/LYN/PDE3B/CFLAR/CAT/HADH/IRS4/ATP6V1B2/IL1B/HADHA	49
BP	GO:0051403	stress-activated MAPK cascade	51/2112	286/18670	0.000657	0.005916	0.004275	SFRP1/SLAMF1/RASGRP1/CCL19/TPD52L1/SEMA3A/CCR7/SKP1/MAP3K11/LGALS9/NOD2/CRYAB/TNIP2/MAP3K8/RIPK2/EGFR/SPHK1/MAP4K1/CCL21/HGF/CD27/EPHB1/CD40LG/MAPK13/ARL6IP5/NFKB1/FZD4/FOXO1/FZD7/MFHAS1/ZMYND11/MAP3K2/LEP/ZFP36L1/PTGER4/PAK1/DACT1/SYK/PHLPP1/IKBKG/PINK1/MAPKAPK2/PTPN22/IL1RN/NOD1/HIPK2/NCF1/PRMT1/PBK/TLR6/IL1B	51
BP	GO:0000082	G1/S transition of mitotic cell cycle	50/2112	279/18670	0.0006574	0.005916	0.004275	CDKN2C/TFDP2/CCND2/INHBA/PPP3CA/BID/CRLF3/KANK2/RRM2/PSME1/EGFR/BTN2A2/CDC45/PTPN6/E2F8/FHL1/CDK1/EZH2/MCM5/ZPR1/BACH1/HYAL1/PLK2/BRD4/CDC7/MCM2/CCNB1/DACT1/CCND1/ACVR1/DBF4/GFI1/FBXO5/CUL2/TYMS/POLE2/RB1/MCM4/CUL4B/PKD2/PRMT1/PCBP4/TP53/CCL2/KHDRBS1/PIM2/CCNE2/AURKA/MCM10/PML	50
BP	GO:0034103	regulation of tissue remodeling	21/2112	88/18670	0.0006615	0.005941	0.004292	SFRP1/TNFAIP3/TNFRSF11B/CSK/IL15/LTBP3/PPP3CA/ADAM8/TFRC/EGFR/THBS4/CA2/LEP/SYK/PDK4/IL6/CD38/INPP5D/IL18/S1PR1/TP53	21
BP	GO:0046851	negative regulation of bone remodeling	7/2112	15/18670	0.000662	0.005941	0.004292	SFRP1/TNFAIP3/TNFRSF11B/CSK/IL6/CD38/INPP5D	7
BP	GO:0042088	T-helper 1 type immune response	13/2112	43/18670	0.000663	0.005941	0.004292	RELB/XCL1/CCR2/IL27RA/SEMA4A/CCL19/IL4R/RIPK2/LEF1/CD80/IL18/IL1R1/IL1B	13
BP	GO:0001914	regulation of T cell mediated cytotoxicity	11/2112	33/18670	0.0006833	0.006088	0.004399	XCL1/PTPRC/HLA-F/HLA-A/IL7R/HLA-C/HLA-G/HLA-E/HLA-B/FAM49B/LILRB1	11
BP	GO:0002717	positive regulation of natural killer cell mediated immunity	11/2112	33/18670	0.0006833	0.006088	0.004399	RASGRP1/HLA-F/HLA-G/MICB/CRTAM/HLA-E/SH2D1A/CD160/CD226/CADM1/VAV1	11
BP	GO:0010464	regulation of mesenchymal cell proliferation	11/2112	33/18670	0.0006833	0.006088	0.004399	BMP4/STAT1/SOX9/SIX1/BMPR1A/SHOX2/NFIB/PTN/LRP5/FGF9/LMNA	11
BP	GO:0030851	granulocyte differentiation	11/2112	33/18670	0.0006833	0.006088	0.004399	LBR/HCLS1/CBFA2T3/GATA2/EVI2B/LEF1/ADIPOQ/SPI1/INPP5D/TESC/CEBPA	11
BP	GO:0051048	negative regulation of secretion	44/2112	238/18670	0.0006947	0.00617	0.004458	SFRP1/TNFAIP3/CCR2/GBP1/IL27RA/TLR8/HLA-F/TNFRSF1B/RHBDF2/INHBA/PPP3CA/CD200/ANGPT1/CD74/LGALS9/BTN2A2/SRGN/ADA/KLF7/IDH2/NMB/IL13RA2/RAB33B/RHBDF1/PTPN11/NOTCH1/LEP/PTGER4/ADIPOQ/SERPINB1/TNFRSF4/MAOB/PTPN22/ANXA4/NR1H3/PPP1R11/HADH/LRRC32/TLR6/IL1B/PML/RAB11FIP1/LILRB1/NLRP3	44
BP	GO:0072577	endothelial cell apoptotic process	17/2112	65/18670	0.0006952	0.00617	0.004458	NDNF/TNFAIP3/ITGA4/AKR1C3/ANGPT1/HLA-G/ICAM1/TNIP2/CD40/SCG2/GATA2/CD160/CD40LG/ANGPTL4/FOXO3/KDR/CCL2	17
BP	GO:0061008	hepaticobiliary system development	29/2112	138/18670	0.0006955	0.00617	0.004458	TNFAIP3/SOX9/GLI3/COBL/RPS6KA1/EGFR/ADA/TGFBR3/E2F8/HGF/EZH2/ACAT1/PCK1/PTN/SMAD3/NOTCH1/SEC63/RGN/PIK3CA/CCND1/HFE/NIPBL/TYMS/JARID2/CEBPA/PKD2/CFLAR/AURKA/LIMS2	29
BP	GO:0001952	regulation of cell-matrix adhesion	26/2112	119/18670	0.0006978	0.006181	0.004466	PIK3R1/CD3E/SFRP1/EPHA3/LIMCH1/DDR2/CCR7/EMP2/ITGB1BP1/CD36/DAG1/DLC1/CCL21/SKAP1/EFNA5/SMAD3/MYOC/PPM1F/PLEKHA2/RHOD/FERMT1/SEMA3E/KDR/CASK/COL16A1/MMP12	26
BP	GO:0044839	cell cycle G2/M phase transition	48/2112	266/18670	0.0007131	0.006308	0.004557	PSMB9/PSMB8/PSMB10/DTL/TPD52L1/CETN2/SKP1/CCNB2/HMMR/PLK1/TPX2/BORA/TUBA4A/PSME1/CDC14B/MELK/BLM/CDC25B/FHL1/SMARCD3/CDK1/CCNA2/CEP135/TUBB4A/PBX1/NEK2/BACH1/CDK14/BRD4/DONSON/CDC7/CCNB1/MECP2/CCND1/FBXO5/CNTRL/CENPF/MIIP/AURKB/ENSA/CEP63/FBXL7/SYF2/NAE1/TP53/KHDRBS1/AURKA/TOPBP1	48
BP	GO:0044786	cell cycle DNA replication	18/2112	71/18670	0.0007331	0.006467	0.004672	LIG1/CDC45/E2F8/STAG2/MCM5/RFC3/ZPR1/GINS1/FEN1/ATRX/DONSON/CDC7/MCM2/TERF1/DBF4/FBXO5/POLE2/MCM4	18
BP	GO:1904427	positive regulation of calcium ion transmembrane transport	18/2112	71/18670	0.0007331	0.006467	0.004672	CXCL9/XCL1/SRI/CACNA2D1/ANK2/CXCL10/PLCG2/TRPC1/CD19/ATP1B1/RGN/CXCL11/FGF14/P2RY6/APLNR/PKD2/GSTO1/GSTM2	18
BP	GO:0002431	Fc receptor mediated stimulatory signaling pathway	30/2112	145/18670	0.0007444	0.006557	0.004737	PIK3R1/PTPRC/CSK/CD247/CD3G/WASL/FGR/PLCG2/WAS/CD226/DOCK1/NCKAP1L/CYFIP2/VAV1/IGLC1/IGLV1-44/PIK3CA/HSP90AB1/PAK1/MYO1C/SYK/IGHG1/PLSCR1/LYN/HCK/ARPC1A/WASF2/ACTR3/VAV3/ACTR2	30
BP	GO:0060541	respiratory system development	38/2112	198/18670	0.0007542	0.006633	0.004793	BMP4/IGFBP5/LRP6/DLG5/FGF18/SOX9/GLI3/LTBP3/SKI/FGF7/ZFPM2/SIX1/BMPR1A/ADAMTSL2/YAP1/EGFR/PDPN/ADA/DAG1/NFIB/PTN/LEF1/RBP4/NOTCH1/TIMELESS/PPP1CA/TNS3/FGF9/TGFB3/TULP3/RCN3/CEBPA/FSTL3/KCNAB1/SMCHD1/HOXA5/THRA/CTSH	38
BP	GO:0032481	positive regulation of type I interferon production	19/2112	77/18670	0.000758	0.006657	0.00481	IRF1/TLR8/STAT1/ZBTB20/MYD88/NFKB2/TLR2/IRF7/IFIH1/RIPK2/CREBBP/PLCG2/DDX58/NFKB1/PTPN11/SYK/POLR2L/PTPN22/MMP12	19
BP	GO:0048661	positive regulation of smooth muscle cell proliferation	23/2112	101/18670	0.0007592	0.006657	0.00481	CCL5/BMP4/IGFBP5/IGF1/STAT1/ABCC4/BMPR1A/JAK2/PDGFD/HDAC4/AKR1B1/EGFR/HBEGF/FGF2/DNMT1/PAK1/P2RY6/FGF9/IL6/CYBA/IL18/S1PR1/TGM2	23
BP	GO:0051402	neuron apoptotic process	44/2112	239/18670	0.0007601	0.006657	0.00481	NDNF/CRLF1/GDF5/CORO1A/NQO1/NTRK2/ANGPT1/BID/AXL/SIGMAR1/OXR1/MAP3K11/SIX1/ADAM8/JAK2/HDAC4/ITSN1/LANCL1/CX3CR1/TP63/SOD1/ZPR1/FAM162A/PIK3CA/MECP2/TFAP2A/HSP90AB1/PARP1/STXBP1/TGFB3/PINK1/BACE1/APAF1/DDIT3/FOXO3/RB1/TRIM2/HIPK2/DIO3/PIGT/NAE1/TP53/CCL2/CHL1	44
BP	GO:0045010	actin nucleation	14/2112	49/18670	0.0007833	0.006851	0.00495	CORO1A/ARPIN/WASL/WAS/GMFG/ARPC5L/LMOD1/AP1AR/ARPC1A/ABI2/ACTR3/IQGAP2/GSN/ACTR2	14
BP	GO:0000187	activation of MAPK activity	31/2112	152/18670	0.00079	0.006899	0.004985	PTPRC/IGF1/PLCE1/CXCR4/CCL19/DUSP5/LPAR1/CD74/MAP3K11/NOD2/RIPK2/FGF2/MAP4K1/CSPG4/GHR/CDK1/HGF/CD40LG/SOD1/PTPN11/MAP3K2/FPR1/SYK/IKBKG/TGFB3/MAPKAPK2/DUSP6/NOD1/SHC2/CD81/IL1B	31
BP	GO:0043302	positive regulation of leukocyte degranulation	9/2112	24/18670	0.0007965	0.006946	0.005019	HLA-F/ITGB2/IL4R/GATA2/FGR/STX4/SYK/STXBP1/GAB2	9
BP	GO:0007584	response to nutrient	41/2112	219/18670	0.0008024	0.006987	0.005049	CD3E/SFRP1/TNFRSF11B/PENK/NQO1/STAT1/IL15/PIM1/KYNU/AKR1C3/OXCT1/KANK2/NOD2/CXCL10/TRIM24/EGFR/ADA/PTN/SOD1/LIPG/LEP/SLC8A1/ALPL/ADIPOQ/CCND1/APAF1/MAP1B/TYMS/BCL11A/BCKDHB/RYR3/ENSA/CYBA/IGFBP2/PANX1/CAT/ERCC1/ALAD/GSN/IL1B/P2RY4	41
BP	GO:0046626	regulation of insulin receptor signaling pathway	17/2112	66/18670	0.0008392	0.007298	0.005273	ENPP1/PID1/PIK3R1/PTPRE/PRKCQ/NUCKS1/PRKCB/PTPN2/SOCS1/CISH/SOCS2/PTPN11/KANK1/LEP/PAK1/SORBS1/IL1B	17
BP	GO:0071622	regulation of granulocyte chemotaxis	13/2112	44/18670	0.0008447	0.007317	0.005287	CCL5/XCL1/RAC2/CCL19/CCR7/JAM3/CD74/DYSF/THBS4/CXCL8/CCL21/CAMK1D/NCKAP1L	13
BP	GO:0048736	appendage development	35/2112	179/18670	0.000845	0.007317	0.005287	GDF5/BMP4/LRP6/HOXC10/HOXA10/TMEM231/SOX9/ZBTB16/GLI3/SKI/PAM/BMPR1A/COMP/SHOX2/ZNF358/RECK/CREBBP/BAK1/ASPH/CHST11/TP63/PITX1/PBX1/LEF1/ATRX/NOTCH1/TFAP2A/FGF9/HOXD10/NIPBL/TULP3/FZD6/MEGF8/HOXA11/PRKAB1	35
BP	GO:0060173	limb development	35/2112	179/18670	0.000845	0.007317	0.005287	GDF5/BMP4/LRP6/HOXC10/HOXA10/TMEM231/SOX9/ZBTB16/GLI3/SKI/PAM/BMPR1A/COMP/SHOX2/ZNF358/RECK/CREBBP/BAK1/ASPH/CHST11/TP63/PITX1/PBX1/LEF1/ATRX/NOTCH1/TFAP2A/FGF9/HOXD10/NIPBL/TULP3/FZD6/MEGF8/HOXA11/PRKAB1	35
BP	GO:0071496	cellular response to external stimulus	58/2112	339/18670	0.0008497	0.007348	0.005309	SFRP1/PTPRC/IRF1/PENK/TLR8/GABARAPL1/SOX9/SIPA1/IL15/ITGA4/PIM1/MYD88/AKR1C3/UPP1/AXL/CBS/KANK2/ICAM1/HDAC4/CD40/TRIM24/EGFR/GABARAPL2/DAG1/DAP/SIK1/BAK1/PCK1/PTN/TLR5/SOD1/KCNJ2/NFKB1/CASP1/PMAIP1/FOXO1/PTPN11/MAP3K2/CASP5/PIEZO2/LEP/HIGD1A/DSC2/ATP1A2/PTGER4/FOSL1/PDK4/HFE/BCL11A/RYR3/CYBA/PRKD1/SESN1/LYN/TP53/IL1B/P2RY4/TXN2	58
BP	GO:0032613	interleukin-10 production	15/2112	55/18670	0.0008807	0.007603	0.005493	XCL1/IDO1/SASH3/TLR2/IRF4/LGALS9/NOD2/CLEC7A/HGF/PDCD1LG2/CD40LG/CD83/SYK/ISG15/LILRB1	15
BP	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	10/2112	29/18670	0.0008829	0.007603	0.005493	TFDP2/RRM2/CDC45/ZPR1/BACH1/BRD4/GFI1/FBXO5/TYMS/RB1	10
BP	GO:0070102	interleukin-6-mediated signaling pathway	10/2112	29/18670	0.0008829	0.007603	0.005493	STAT1/PTPN2/JAK2/PTPN11/IL6ST/GFI1/SPI1/IL6/FER/CEBPA	10
BP	GO:0051017	actin filament bundle assembly	31/2112	153/18670	0.0008855	0.007615	0.005502	LCP1/PIK3R1/SFRP1/LIMCH1/ADD3/LPAR1/PFN2/ITGB1BP1/RHOF/DLC1/TAC1/WAS/PLEK/NOX4/ARHGEF10/PLS3/SMAD3/CORO2B/TNFAIP1/GPR65/MYOC/PPM1F/PTGER4/PAK1/DPYSL3/SORBS1/TGFB3/RHOD/WASF2/S1PR1/PFN1	31
BP	GO:0030204	chondroitin sulfate metabolic process	12/2112	39/18670	0.0008901	0.007633	0.005515	NDNF/SPOCK2/CHST15/CHST3/DCN/BGN/CSPG4/CHST11/VCAN/HYAL1/UGDH/IDUA	12
BP	GO:0030501	positive regulation of bone mineralization	12/2112	39/18670	0.0008901	0.007633	0.005515	NELL1/BMP4/BMPR1A/PTN/SMAD3/KL/SLC8A1/TFAP2A/ACVR1/TGFB3/ATRAID/ISG15	12
BP	GO:0032755	positive regulation of interleukin-6 production	22/2112	96/18670	0.0008946	0.007661	0.005535	TLR8/LILRB2/ZBTB20/MYD88/TLR2/CD74/LGALS9/NOD2/CD36/IFIH1/RIPK2/CLEC7A/MAPK13/DDX58/PTPN11/SYK/IL6/CYBA/IL1RN/NOD1/TLR6/IL1B	22
BP	GO:1901654	response to ketone	37/2112	193/18670	0.0008968	0.007669	0.005541	SFRP1/CCL19/AKR1C3/CCR7/TLR2/AR/ICAM1/YAP1/AKR1B1/EGFR/TGFBR3/MAP4K1/CCL21/PLN/PCK1/PTN/FOXO1/EFNA5/PSPH/CSN1S1/PTGFR/PTGER4/P2RY6/CCND1/FOSL1/PARP1/TGFB3/MAOB/CD38/TYMS/NR1H3/FOXO3/CYBA/RWDD1/CFLAR/KIF1B/P2RY4	37
BP	GO:0071674	mononuclear cell migration	21/2112	90/18670	0.0009049	0.007711	0.005572	CCL5/SLAMF8/XCL1/CCR2/CCL19/CCL13/PDGFD/CXCL10/CCL21/CCR1/CCL18/NBL1/PECAM1/CCL7/IL6/FPR2/LYN/CCL17/CCL2/CCL23/PLA2G7	21
BP	GO:0010811	positive regulation of cell-substrate adhesion	26/2112	121/18670	0.0009076	0.007711	0.005572	NDNF/CD3E/SFRP1/SPOCK2/CCR7/EMP2/ITGB1BP1/ECM2/JAK2/CD36/DAG1/COL8A1/CCL21/EDIL3/PTN/DOCK1/SKAP1/SMAD3/HSD17B12/MYOC/PPM1F/PLEKHA2/FERMT1/KDR/LIMS2/COL16A1	26
BP	GO:0042533	tumor necrosis factor biosynthetic process	11/2112	34/18670	0.0009079	0.007711	0.005572	CCR2/JAK2/CLEC7A/AKAP12/CX3CR1/IFNG/SYK/HSPB1/MAPKAPK2/UBE2J1/LILRB1	11
BP	GO:0042534	regulation of tumor necrosis factor biosynthetic process	11/2112	34/18670	0.0009079	0.007711	0.005572	CCR2/JAK2/CLEC7A/AKAP12/CX3CR1/IFNG/SYK/HSPB1/MAPKAPK2/UBE2J1/LILRB1	11
BP	GO:0070670	response to interleukin-4	11/2112	34/18670	0.0009079	0.007711	0.005572	IL2RG/XCL1/CORO1A/PTPN2/IL4R/TCF7/LEF1/MCM2/HSP90AB1/ALAD/PML	11
BP	GO:0043087	regulation of GTPase activity	77/2112	479/18670	0.0009182	0.007788	0.005627	CCL5/CXCL13/XCL1/SFRP1/EPHA3/RASGRP1/ARHGDIB/FAM13A/ARHGAP25/CCL19/SIPA1/SEMA4D/TBC1D16/DOCK10/NTRK2/CCL13/RASGRP3/CCR7/TBC1D5/MAPRE2/ITGB1BP1/RASIP1/ICAM1/RABGAP1/ACAP1/CD40/HTR2B/TBC1D9/DLC1/STARD8/DENND1A/CCL21/ARHGAP17/ERBB2/TBC1D8B/AGAP1/RHOH/ARHGAP22/EZH2/ASAP2/DOCK1/NCKAP1L/SOD1/TBC1D1/ARHGEF10/CCL18/RABGAP1L/GMIP/ARHGEF12/NET1/EFNA5/DOCK2/VAV1/GPR65/RASA2/CHN1/RACGAP1/ECT2/GDI1/RHOG/RGN/CCL7/DEPDC1/ARHGAP4/PRKG1/RALBP1/RGS1/CCL17/S1PR1/RAB11FIP2/NUP50/CCL2/SEC23B/CCL23/IQGAP2/VAV3/ARHGAP12	77
BP	GO:0032495	response to muramyl dipeptide	8/2112	20/18670	0.0009501	0.007993	0.005775	TNFAIP3/NOD2/RIPK2/NFKBIA/NOTCH1/PTPN22/LDOC1/NOD1	8
BP	GO:0033194	response to hydroperoxide	8/2112	20/18670	0.0009501	0.007993	0.005775	OXR1/JAK2/CD36/SP1/GPX3/STX4/CD38/PRKD1	8
BP	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process	8/2112	20/18670	0.0009501	0.007993	0.005775	CCR2/JAK2/CLEC7A/AKAP12/IFNG/SYK/HSPB1/MAPKAPK2	8
BP	GO:0051767	nitric-oxide synthase biosynthetic process	8/2112	20/18670	0.0009501	0.007993	0.005775	STAT1/TLR2/NOD2/JAK2/AKAP12/IFNG/KDR/CCL2	8
BP	GO:0051769	regulation of nitric-oxide synthase biosynthetic process	8/2112	20/18670	0.0009501	0.007993	0.005775	STAT1/TLR2/NOD2/JAK2/AKAP12/IFNG/KDR/CCL2	8
BP	GO:0072234	metanephric nephron tubule development	8/2112	20/18670	0.0009501	0.007993	0.005775	STAT1/SOX9/YAP1/ACAT1/WWTR1/FAT4/PKD2/POU3F3	8
BP	GO:0032233	positive regulation of actin filament bundle assembly	16/2112	61/18670	0.0009551	0.008002	0.005781	SFRP1/LIMCH1/LPAR1/PFN2/ITGB1BP1/TAC1/PLEK/NOX4/ARHGEF10/SMAD3/GPR65/MYOC/PPM1F/PAK1/TGFB3/PFN1	16
BP	GO:0034113	heterotypic cell-cell adhesion	16/2112	61/18670	0.0009551	0.008002	0.005781	LCK/PTPRC/CD2/ITGB7/LILRB2/ITGA4/CD200/ITGB2/PARVA/SKAP1/DSC2/ADIPOQ/ITGAX/IL1RN/ITGAV/IL1B	16
BP	GO:0050701	interleukin-1 secretion	16/2112	61/18670	0.0009551	0.008002	0.005781	AIM2/TNFAIP3/TLR8/CCL19/CCR7/LGALS9/NOD2/CD36/RIPK2/S100A13/CASP1/SERPINB1/PANX1/TLR6/PML/NLRP3	16
BP	GO:0044843	cell cycle G1/S phase transition	52/2112	298/18670	0.0009754	0.00815	0.005888	CDKN2C/TFDP2/CCND2/INHBA/PPP3CA/BID/CRLF3/KANK2/RRM2/PSME1/EGFR/BTN2A2/CDC45/PTPN6/E2F8/FHL1/CDK1/CCNA2/EZH2/MCM5/ZPR1/BACH1/HYAL1/PLK2/BRD4/CDC7/MCM2/CCNB1/DACT1/CCND1/ACVR1/DBF4/GFI1/FBXO5/PAF1/CUL2/TYMS/POLE2/RB1/MCM4/CUL4B/PKD2/PRMT1/PCBP4/TP53/CCL2/KHDRBS1/PIM2/CCNE2/AURKA/MCM10/PML	52
BP	GO:1901987	regulation of cell cycle phase transition	77/2112	480/18670	0.0009754	0.00815	0.005888	PSMB9/CDKN2C/PSMB8/TFDP2/CDKN1C/PSMB10/DTL/CCND2/CETN2/BUB1/SKP1/BID/HMMR/UBE2C/NDC80/KANK2/MAD2L1/PLK1/TPX2/TUBA4A/PSME1/EGFR/CDC14B/BTN2A2/CDC45/PTPN6/BLM/E2F8/CDC25B/FHL1/TPR/SMARCD3/CDK1/DLGAP5/ZNF207/EZH2/CEP135/BUB1B/TUBB4A/PBX1/NEK2/HYAL1/PLK2/UBE2D1/BRD4/DONSON/CDC7/ZFP36L1/CCNB1/MECP2/DACT1/CCND1/DBF4/FBXO5/CNTRL/PAF1/CENPF/TTK/MIIP/AURKB/RB1/CEP63/CDC20/CUL4B/FBXL7/SYF2/PKD2/NAE1/ZFP36L2/PRMT1/PCBP4/TRIP13/TP53/CCL2/AURKA/TOPBP1/PML	77
BP	GO:0036293	response to decreased oxygen levels	62/2112	370/18670	0.000989	0.008252	0.005963	PSMB9/NDNF/SFRP1/PSMB8/PENK/CXCR4/PSMB10/TLR2/CBFA2T3/PAM/ICAM1/ADAM8/CRYAB/PSME1/CPEB1/ADA/TGFBR3/CREBBP/KCNK2/CCNA2/PCK1/PTN/PLAT/NOX4/PMAIP1/ATP1B1/BACH1/SMAD3/ANGPTL4/FAM162A/NOTCH1/LEP/HIGD1A/ZFP36L1/ARNT/CCNB1/PDLIM1/MECP2/SLC8A1/PAK1/ADIPOQ/TGFB3/PINK1/APAF1/CD38/CUL2/FOXO3/LMNA/UCP2/CYBA/VEGFB/ANG/APOLD1/HIPK2/CFLAR/CAT/ALAD/TP53/BNIP3L/HP1BP3/PML/TXN2	62
BP	GO:0008286	insulin receptor signaling pathway	29/2112	141/18670	0.0009971	0.008309	0.006003	ENPP1/PID1/PIK3R1/PTPRE/PRKCQ/SH2B2/NUCKS1/PRKCB/PTPN2/TCIRG1/SOCS1/CISH/SOCS2/ZNF106/FOXO1/PTPN11/KL/KANK1/LEP/PIK3CA/PAK1/PDK4/SORBS1/PIK3R3/FER/FOXO3/IRS4/ATP6V1B2/IL1B	29
BP	GO:0060038	cardiac muscle cell proliferation	17/2112	67/18670	0.001008	0.008387	0.00606	PIM1/FOXC1/MEIS1/ZFPM2/BMPR1A/YAP1/FGF2/TGFBR3/CDK1/KCNK2/RBP4/NOTCH1/CCNB1/HEY2/FGF9/JARID2/TENM4	17
BP	GO:0019079	viral genome replication	26/2112	122/18670	0.001032	0.008573	0.006194	CCL5/SLPI/NUCKS1/APOBEC3G/OAS1/ISG20/SRPK1/IFI27/OASL/CXCL8/CXCR6/FAM111A/TOP2A/NOTCH1/FBXL2/VCP/ADAR/MPHOSPH8/OAS3/TRIM38/IFIT5/PLSCR1/MX1/ZC3HAV1/CCL2/ISG15	26
BP	GO:0031100	animal organ regeneration	18/2112	73/18670	0.001041	0.008632	0.006237	LCP1/GLI3/AXL/ANXA3/EGFR/TGFBR3/CDK1/BAK1/HGF/CCNA2/EZH2/NOTCH1/RGN/FLT3/CCND1/HFE/TYMS/AURKA	18
BP	GO:0050688	regulation of defense response to virus	18/2112	73/18670	0.001041	0.008632	0.006237	TRAF3/AIM2/TNFAIP3/BIRC3/STAT1/IL15/APOBEC3G/HTRA1/MICB/TSPAN6/DDX58/HERC5/DDX60/TRIM38/IL2RA/IL1B/MMP12/LILRB1	18
BP	GO:0007077	mitotic nuclear envelope disassembly	6/2112	12/18670	0.001049	0.008659	0.006256	PRKCB/CCNB2/VRK1/PLK1/CDK1/CCNB1	6
BP	GO:0070486	leukocyte aggregation	6/2112	12/18670	0.001049	0.008659	0.006256	STK10/S100A9/RAC2/SEMA4D/ZAP70/IL1B	6
BP	GO:1902224	ketone body metabolic process	6/2112	12/18670	0.001049	0.008659	0.006256	OXCT1/ACSS3/ACAT1/BDH2/BDH1/SLC27A5	6
BP	GO:0001889	liver development	28/2112	135/18670	0.001055	0.008694	0.006282	TNFAIP3/SOX9/GLI3/COBL/RPS6KA1/EGFR/ADA/TGFBR3/E2F8/HGF/EZH2/ACAT1/PCK1/PTN/SMAD3/NOTCH1/SEC63/RGN/PIK3CA/CCND1/HFE/TYMS/JARID2/CEBPA/PKD2/CFLAR/AURKA/LIMS2	28
BP	GO:0001570	vasculogenesis	19/2112	79/18670	0.001059	0.008715	0.006297	NTRK2/EMP2/RASIP1/ZFPM2/SGPL1/ACKR3/YAP1/TGFBR3/TMEM100/FZD4/NOTCH1/ZFP36L1/HEY2/APLNR/HEY1/KDR/GJC1/WARS2/ITGAV	19
BP	GO:0001780	neutrophil homeostasis	7/2112	16/18670	0.001062	0.008724	0.006304	CCR2/JAM3/AXL/PIK3CD/IL6/SH2B3/MERTK	7
BP	GO:0002475	antigen processing and presentation via MHC class Ib	7/2112	16/18670	0.001062	0.008724	0.006304	HLA-F/HLA-A/TAP2/HLA-C/HLA-G/HLA-E/HLA-B	7
BP	GO:0060070	canonical Wnt signaling pathway	57/2112	335/18670	0.001072	0.008787	0.006349	PSMB9/SFRP1/PSMB8/LRP6/GPC5/WNT5B/ASPM/RBMS3/PSMB10/SOX9/GLI3/IGFBP6/WLS/ZBED2/YAP1/PSME1/EGFR/UBE2B/RECK/TCF7/TCF7L2/SOX2/LRP5/CDH2/RYK/PLEKHA4/NFKB1/FZD4/LEF1/FOXO1/CDK14/SMAD3/DIXDC1/FZD7/DAAM2/NOTCH1/ARNTL/VCP/KANK1/PPP1CA/TCF7L1/DACT1/FGF9/WWTR1/FZD6/DDIT3/FOXO3/FERMT1/IGFBP2/RNF146/DVL1/DKK3/NLE1/FZD2/FRAT1/NPHP4/TBL1X	57
BP	GO:0060485	mesenchyme development	49/2112	278/18670	0.001075	0.008807	0.006363	KITLG/SFRP1/EPHA3/BMP4/LRP6/SEMA4A/DLG5/STAT1/SOX9/SEMA4D/FOXC1/SEMA3A/PPP2CA/ZFPM2/SIX1/BMPR1A/SIX2/HTR2B/YAP1/MEOX1/PDPN/DAG1/TGFBR3/TMEM100/HGF/EZH2/DCHS1/LEF1/FAM172A/SEMA3F/SMAD3/LDLRAD4/NOTCH1/ZFP36L1/HEY2/ACVR1/EDNRB/FGF9/TGFB3/WWTR1/IL6/CFL1/SEMA4F/SEMA3E/HEY1/PKD2/SEMA6B/IL1B/HOXA5	49
BP	GO:2001236	regulation of extrinsic apoptotic signaling pathway	31/2112	155/18670	0.001107	0.009055	0.006542	SFRP1/PTPRC/TNFAIP3/BMP4/IGF1/TIMP3/EYA4/TRAF1/INHBA/BID/TNFSF10/AR/EYA2/ICAM1/SCG2/YAP1/DEPTOR/HGF/TCF7L2/PMAIP1/ZMYND11/PPP1CA/STX4/ACVR1/CTTN/G0S2/LMNA/CFLAR/ITGAV/IL1B/PML	31
BP	GO:0072006	nephron development	29/2112	142/18670	0.00112	0.009105	0.006579	BMP4/PLCE1/STAT1/SOX9/GLI3/FOXC1/ANGPT1/SULF1/SIX1/PDGFD/SIX2/YAP1/FGF2/MAGI2/ACAT1/NUP160/PBX1/DCHS1/NOTCH1/PECAM1/ADIPOQ/WWTR1/FAT4/PKD2/CFLAR/POU3F3/HOXA11/GPR4/AHI1	29
BP	GO:1902904	negative regulation of supramolecular fiber organization	29/2112	142/18670	0.00112	0.009105	0.006579	CORO1A/CLU/ADD3/ARPIN/TMOD1/PFN2/CRYAB/TMSB10/CKAP2/DLC1/FGF13/WAS/TUBB4A/GMFG/CORO2B/MYOC/KANK1/LMOD1/CAMSAP2/MAP1B/CAPZA1/VILL/CLIP3/WASF2/S1PR1/PFN1/SPTBN1/GSN/CDH5	29
BP	GO:0050901	leukocyte tethering or rolling	9/2112	25/18670	0.001121	0.009105	0.006579	CCR2/ITGB7/ITGA4/SELL/SELE/CCL21/CX3CR1/LEP/SELPLG	9
BP	GO:0072677	eosinophil migration	9/2112	25/18670	0.001121	0.009105	0.006579	CCL5/CCL13/ADAM8/SCG2/HRH1/PTGER4/CCL7/CCL2/CCL23	9
BP	GO:0090025	regulation of monocyte chemotaxis	9/2112	25/18670	0.001121	0.009105	0.006579	CCL5/SLAMF8/CCR2/CXCL10/CCR1/NBL1/FPR2/LYN/PLA2G7	9
BP	GO:0019835	cytolysis	12/2112	40/18670	0.001142	0.009245	0.00668	GZMA/PRF1/APOL1/GZMB/LYZ/GZMH/MICB/MMD/C7/KRT6A/LILRB1/C6	12
BP	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	12/2112	40/18670	0.001142	0.009245	0.00668	CXCL9/XCL1/SRI/CXCL10/TRPC1/CD19/CXCL11/P2RY6/APLNR/PKD2/GSTO1/GSTM2	12
BP	GO:0070482	response to oxygen levels	65/2112	394/18670	0.001142	0.009245	0.00668	PSMB9/NDNF/SFRP1/PSMB8/PENK/CXCR4/PSMB10/LPAR1/TLR2/CBFA2T3/PAM/ICAM1/ADAM8/CRYAB/PSME1/CPEB1/ADA/TGFBR3/CREBBP/CYB5R4/KCNK2/CCNA2/PCK1/PTN/PLAT/NOX4/PMAIP1/ATP1B1/BACH1/FOXO1/SMAD3/ANGPTL4/FAM162A/NOTCH1/LEP/HIGD1A/ZFP36L1/ARNT/CCNB1/PDLIM1/MECP2/SLC8A1/PAK1/ADIPOQ/TGFB3/PINK1/APAF1/CD38/CUL2/FOXO3/LMNA/UCP2/CYBA/VEGFB/ANG/APOLD1/HIPK2/CFLAR/CAT/ALAD/TP53/BNIP3L/HP1BP3/PML/TXN2	65
BP	GO:0051146	striated muscle cell differentiation	51/2112	293/18670	0.001148	0.009278	0.006704	CXCL9/SGCB/BMP4/UCHL1/IGFBP5/IGF1/PLEKHO1/MYH10/TMOD1/SKI/PPP3CA/CDON/CBY1/IL4R/SIX1/DYSF/HDAC4/COMP/SHOX2/CXCL10/CDK1/SIK1/EZH2/SORBS2/PDLIM5/NOX4/AFG3L2/CDH2/SGCD/CD53/CEACAM5/BHLHE41/FZD7/CD9/NOTCH1/LMOD1/CCNB1/HEY2/SLC8A1/PAK1/POPDC2/ACVR1/KRT19/AKAP13/MYH11/LMNA/RB1/CD81/WDR1/CFLAR/ALPK3	51
BP	GO:0002260	lymphocyte homeostasis	16/2112	62/18670	0.001154	0.009304	0.006722	TNFAIP3/CORO1A/DOCK10/SH2B2/LAT/CD74/CCNB2/TCIRG1/LGALS9/ADA/BAK1/NCKAP1L/PMAIP1/LYN/IL2RA/TNFRSF17	16
BP	GO:0046824	positive regulation of nucleocytoplasmic transport	16/2112	62/18670	0.001154	0.009304	0.006722	PIK3R1/ZIC1/GLI3/HCLS1/CPSF6/TPR/TCF7L2/ZPR1/SMAD3/ECT2/LEP/IFNG/TP53/KHDRBS1/IL1B/XPO4	16
BP	GO:0044262	cellular carbohydrate metabolic process	50/2112	286/18670	0.001157	0.009314	0.006729	ENPP1/GK/IGF1/PPP1R3C/NFE2L1/PTPN2/CBFA2T3/EXTL2/DYSF/HDAC4/AKR1B1/HK3/PASK/IDH2/PHKB/PLEK/SIK1/PCK1/PER2/COX11/ACACB/FAM3C/PMAIP1/INPP1/PGD/FOXO1/HRH1/IDUA/NAGK/LEP/IL6ST/PPP1CA/RGN/MECP2/SLC5A3/ADIPOQ/P2RY6/PDK4/SORBS1/AOAH/SCARB2/EXT2/PPIP5K1/B3GNT2/UGP2/FGGY/PTH1R/MANBA/MTMR2/TP53	50
BP	GO:0007292	female gamete generation	28/2112	136/18670	0.001187	0.009542	0.006894	IGF1/ASPM/INHBA/NPR2/IL4R/PLK1/NCAPH/CDC25B/PTN/DAZL/TOP2A/ETV6/LEP/CCNB1/FBXO5/FOSL1/REC8/TTK/FOXO3/ANG/ERCC1/TOB2/TRIP13/NRIP1/AURKA/YBX2/PARN/PTX3	28
BP	GO:0002701	negative regulation of production of molecular mediator of immune response	11/2112	35/18670	0.00119	0.009542	0.006894	XCL1/HLA-F/ANGPT1/CD96/TBX21/IL13RA2/HFE/TGFB3/SPINK5/THOC1/LILRB1	11
BP	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	10/2112	30/18670	0.001191	0.009542	0.006894	RASGRP1/HLA-F/MICB/CRTAM/HLA-E/SH2D1A/CD160/CD226/CADM1/VAV1	10
BP	GO:0050869	negative regulation of B cell activation	10/2112	30/18670	0.001191	0.009542	0.006894	SFRP1/CTLA4/TNFAIP3/INHBA/SAMSN1/MNDA/BTK/INPP5D/LYN/THOC1	10
BP	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	22/2112	98/18670	0.001195	0.009561	0.006908	CTSF/CD74/DYNC1LI2/CTSL/KIF11/KIF15/HLA-DRA/KIF3B/HLA-DPB1/SEC31A/KIF2C/KIF4A/DYNC1I1/HLA-DMA/HLA-DMB/RACGAP1/HLA-DQB2/DCTN6/HLA-DPA1/CAPZA1/OSBPL1A/KIF23	22
BP	GO:0051260	protein homooligomerization	59/2112	351/18670	0.001197	0.009563	0.006909	CD3D/CD3E/GBP1/PRF1/CLU/CD247/GCH1/SKI/BID/SIGMAR1/CBY1/CD3G/PAM/HLA-G/CRYAB/PCBD1/GOLGA2/DYNC1LI2/AKR1C1/BLM/NLGN1/ACAT1/PLN/EHD4/MICU1/TP63/ACACB/KCNJ2/CCDC88C/GPX3/VASP/MAT1A/TNFAIP1/ANGPTL4/COLEC12/VCP/ECT2/PRND/TERF1/ADIPOQ/DPYSL3/CRBN/APAF1/LGI1/RYR3/ACADL/PKD2/CAT/KCTD5/PRMT1/ALAD/TGM2/TK1/TP53/ATXN10/TMCC1/ALDH5A1/KCTD2/ST13	59
BP	GO:0010389	regulation of G2/M transition of mitotic cell cycle	37/2112	196/18670	0.001202	0.009588	0.006928	PSMB9/PSMB8/PSMB10/DTL/CETN2/SKP1/HMMR/PLK1/TPX2/TUBA4A/PSME1/BLM/CDC25B/FHL1/SMARCD3/CDK1/CEP135/TUBB4A/PBX1/NEK2/BRD4/DONSON/CDC7/CCNB1/MECP2/CCND1/FBXO5/CNTRL/CENPF/MIIP/AURKB/CEP63/FBXL7/SYF2/NAE1/AURKA/TOPBP1	37
BP	GO:0010812	negative regulation of cell-substrate adhesion	17/2112	68/18670	0.001204	0.009597	0.006934	PIK3R1/GBP1/SPOCK1/ITGB1BP1/DLC1/FZD4/EFNA5/FZD7/CORO2B/NOTCH1/MYOC/KANK1/AP1AR/FBLN1/SEMA3E/CASK/MMP12	17
BP	GO:0051496	positive regulation of stress fiber assembly	14/2112	51/18670	0.001208	0.009609	0.006943	SFRP1/LIMCH1/LPAR1/PFN2/ITGB1BP1/TAC1/NOX4/ARHGEF10/SMAD3/GPR65/MYOC/PPM1F/PAK1/TGFB3	14
BP	GO:0002761	regulation of myeloid leukocyte differentiation	25/2112	117/18670	0.001226	0.009747	0.007042	KITLG/PIK3R1/SFRP1/INHBA/CD74/PTPN2/HCLS1/IRF7/LILRB3/GATA2/EVI2B/CCR1/LILRB4/LEF1/CA2/ZFP36L1/IFNG/ADIPOQ/INPP5D/TESC/RB1/LYN/FSTL3/TOB2/LILRB1	25
BP	GO:0032418	lysosome localization	18/2112	74/18670	0.001233	0.009775	0.007063	RASGRP1/RAC2/LAT/IL4R/LGALS9/GATA2/FGR/S100A13/IL13RA2/PIK3CD/STXBP2/SYK/STXBP1/BTK/FER/GAB2/LYN/KIF1B	18
BP	GO:1900076	regulation of cellular response to insulin stimulus	18/2112	74/18670	0.001233	0.009775	0.007063	ENPP1/PID1/PIK3R1/PTPRE/PRKCQ/NUCKS1/PRKCB/PTPN2/SOCS1/CISH/SOCS2/PTPN11/KANK1/LEP/PAK1/MYO1C/SORBS1/IL1B	18
BP	GO:0046578	regulation of Ras protein signal transduction	43/2112	238/18670	0.001278	0.01012	0.00731	KITLG/IGF1/RASGRP1/PLCE1/ARHGDIB/CYTH1/SH2B2/ARHGEF18/LPAR1/AUTS2/MAPRE2/RASIP1/KANK2/ARHGEF9/JAK2/ARHGEF26/ITSN1/TIMP2/DLC1/GPR18/DENND1A/ARHGEF3/ARHGEF10/PPP2CB/ARHGEF12/NET1/PSD3/VAV1/TNFAIP1/GPR65/RASA2/NOTCH1/MYOC/ECT2/KANK1/CYTH4/PSD4/AKAP13/DENND4B/LYN/GPR4/VAV3/SCAI	43
BP	GO:0060043	regulation of cardiac muscle cell proliferation	15/2112	57/18670	0.001314	0.01039	0.007504	PIM1/MEIS1/ZFPM2/BMPR1A/YAP1/FGF2/TGFBR3/CDK1/KCNK2/RBP4/NOTCH1/CCNB1/HEY2/FGF9/JARID2	15
BP	GO:0008637	apoptotic mitochondrial changes	26/2112	124/18670	0.001324	0.01044	0.007546	TFDP2/IGF1/CLU/GZMB/BID/TNFSF10/EYA2/TMEM14A/BAK1/HGF/TP63/PPP2CB/PMAIP1/FAM162A/SLC25A4/HIGD1A/ATG3/PINK1/LMNA/SLC25A5/IFIT2/TP53BP2/TP53/BNIP3L/PIM2/MOAP1	26
BP	GO:0014013	regulation of gliogenesis	26/2112	124/18670	0.001324	0.01044	0.007546	CCR2/PRKCH/TNFRSF1B/CXCR4/GPR183/SKI/ZNF365/TLR2/DAG1/ETV5/IDH2/ASPA/CDK1/EZH2/CX3CR1/PTN/CDH2/DAAM2/NOTCH1/IL6ST/IL6/LYN/TENM4/WDR1/RNF10/IL1B	26
BP	GO:0055017	cardiac muscle tissue growth	23/2112	105/18670	0.001331	0.01048	0.007573	IGF1/PIM1/FOXC1/MEIS1/ZFPM2/BMPR1A/YAP1/FGF2/TGFBR3/CDK1/KCNK2/SORBS2/PDLIM5/RBP4/NOTCH1/CCNB1/HEY2/PAK1/FGF9/AKAP13/JARID2/TENM4/S1PR1	23
BP	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	13/2112	46/18670	0.001335	0.01049	0.007576	PTPRD/ICAM1/ITGAL/SELE/NLGN1/CDH2/CADM1/DCHS1/CD6/CEACAM5/FAT4/CD164/TENM4	13
BP	GO:0050706	regulation of interleukin-1 beta secretion	13/2112	46/18670	0.001335	0.01049	0.007576	AIM2/TNFAIP3/TLR8/CCL19/CCR7/LGALS9/NOD2/RIPK2/CASP1/SERPINB1/PANX1/PML/NLRP3	13
BP	GO:0048525	negative regulation of viral process	22/2112	99/18670	0.001376	0.01077	0.007779	CCL5/STAT1/FCN1/SLPI/APOBEC3G/OAS1/ISG20/SRPK1/OASL/FAM111A/TRIM21/MPHOSPH8/OAS3/IFIT5/PLSCR1/TRIM26/MX1/ZC3HAV1/ISG15/GSN/PTX3/PML	22
BP	GO:0019827	stem cell population maintenance	31/2112	157/18670	0.001376	0.01077	0.007779	SFRP1/ASPM/SOX9/SKI/BMPR1A/SIX2/ZNF358/YAP1/GATA2/FGF2/SOX2/PTN/CDH2/TP63/MCPH1/PBX1/ZNF322/FOXO1/FZD7/NOTCH1/MTF2/POLR2L/SPI1/NIPBL/PAF1/ZHX2/FOXO3/DDX6/MED14/ZFP36L2/SS18	31
BP	GO:0061572	actin filament bundle organization	31/2112	157/18670	0.001376	0.01077	0.007779	LCP1/PIK3R1/SFRP1/LIMCH1/ADD3/LPAR1/PFN2/ITGB1BP1/RHOF/DLC1/TAC1/WAS/PLEK/NOX4/ARHGEF10/PLS3/SMAD3/CORO2B/TNFAIP1/GPR65/MYOC/PPM1F/PTGER4/PAK1/DPYSL3/SORBS1/TGFB3/RHOD/WASF2/S1PR1/PFN1	31
BP	GO:0032332	positive regulation of chondrocyte differentiation	8/2112	21/18670	0.001384	0.01079	0.007795	GDF5/FGF18/SOX9/ZBTB16/GLI3/SOX5/SMAD3/HOXA11	8
BP	GO:0035743	CD4-positive, alpha-beta T cell cytokine production	8/2112	21/18670	0.001384	0.01079	0.007795	XCL1/TBX21/IL6/IL18/CD81/IL1R1/IL1B/NLRP3	8
BP	GO:1903055	positive regulation of extracellular matrix organization	8/2112	21/18670	0.001384	0.01079	0.007795	DDR2/SOX9/PDPN/DAG1/SMAD3/IL6/RB1/CFLAR	8
BP	GO:0002637	regulation of immunoglobulin production	16/2112	63/18670	0.001387	0.01079	0.007795	XCL1/PTPRC/IL27RA/SASH3/IL4R/CD40/TFRC/HLA-E/TBX21/IL13RA2/CD40LG/RBP4/STX4/TNFRSF4/IL6/THOC1	16
BP	GO:2000401	regulation of lymphocyte migration	16/2112	63/18670	0.001387	0.01079	0.007795	CCL5/CXCL13/XCL1/CCR2/STK10/IL27RA/ITGA4/CD200/ADAM8/WASL/TNFRSF14/CXCL10/CCL21/CCL7/ADAM10/CCL2	16
BP	GO:0048705	skeletal system morphogenesis	43/2112	239/18670	0.001392	0.01081	0.00781	PLEKHA1/SFRP1/BMP4/LRP6/SCARA3/MGP/FGF18/SOX9/GLI3/LTBP3/FOXC1/SKI/SGPL1/SIX1/COCH/SIX2/COMP/SHOX2/FGR/DHRS3/COL14A1/GLG1/RAB33B/HOXC4/CHST11/LRP5/RYK/HYAL1/SMAD3/IRX5/PAX5/TFAP2A/ALPL/HOXA4/HOXD10/TGFB3/NIPBL/TULP3/MEGF8/NLE1/HOXA11/HOXA5/THRA	43
BP	GO:0045765	regulation of angiogenesis	63/2112	383/18670	0.001451	0.01126	0.008135	CXCL13/SFRP1/TNFAIP3/CCR2/SEMA4A/STAT1/FGF18/CXCR4/FOXC1/PRKCB/EMP2/ITGB1BP1/ITGB2/SULF1/HLA-G/CD40/PRKD2/ANXA3/GATA2/CXCL10/RECK/FGF2/SPHK1/THBS4/DCN/CXCL8/CD160/ERBB2/HGF/SP1/CX3CR1/PPP1R16B/PTN/RRAS/HYAL1/TNMD/ANGPTL4/PLK2/NOTCH1/LEP/AGTR1/MECP2/PRL/APLNR/ITGAX/HSPB1/AKT3/IL6/HSPB6/SEMA3E/VEGFB/PRKD1/PDE3B/HIPK2/KDR/SPINK5/GPR4/IL1B/CDH5/HOXA5/PML/C6/CTSH	63
BP	GO:1902930	regulation of alcohol biosynthetic process	19/2112	81/18670	0.001455	0.01128	0.008147	ABCG1/PMVK/PLEK/ERLIN1/SP1/SOD1/ACACB/NFKB1/SC5D/HRH1/IFNG/NFYA/P2RY6/ERLIN2/GFI1/MBTPS2/DKK3/PTH1R/IL1B	19
BP	GO:0048593	camera-type eye morphogenesis	24/2112	112/18670	0.001458	0.01128	0.008153	BMP4/LRP6/SOX9/GLI3/TSKU/SKI/CDON/MEIS1/COL8A2/COL8A1/BAK1/EPHB1/PTN/LRP5/RBP4/IRX5/TFAP2A/ZHX2/HIPK2/DIO3/ROM1/ABI2/CRYGB/AHI1	24
BP	GO:0031529	ruffle organization	14/2112	52/18670	0.001483	0.01145	0.008271	PLEKHA1/CCR7/PFN2/ICAM1/ARHGEF26/COBL/SH3YL1/CCL21/PLEK/NLGN1/KANK1/RHOG/SNX10/PFN1	14
BP	GO:0032653	regulation of interleukin-10 production	14/2112	52/18670	0.001483	0.01145	0.008271	XCL1/IDO1/SASH3/TLR2/IRF4/LGALS9/NOD2/CLEC7A/HGF/PDCD1LG2/CD40LG/CD83/SYK/LILRB1	14
BP	GO:0045471	response to ethanol	26/2112	125/18670	0.001496	0.01153	0.00833	CDO1/PENK/NQO1/OXCT1/USP46/ICAM1/CDK1/BAK1/CD27/SOD1/RBP4/LEP/RPS4X/CCL7/ADIPOQ/CCND1/SPI1/MAOB/TYMS/SDF4/CAT/TUFM/ALAD/RPL10A/GSN/ACTR2	26
BP	GO:0009952	anterior/posterior pattern specification	40/2112	219/18670	0.001499	0.01153	0.00833	SFRP1/BMP4/LRP6/HOXC10/HOXA10/ZBTB16/PBX3/GLI3/FOXC1/SKI/CDON/HOXC6/BMPR1A/WLS/SIX2/COBL/MEOX1/BPTF/HOXC4/LRP5/PBX1/LEF1/SMAD3/BHLHE41/NOTCH1/HEY2/HOXA4/HOXD10/TULP3/DDIT3/SCMH1/EMX2/HIPK2/HEY1/NLE1/HOXA11/TP53/FEZF2/AURKA/HOXA5	40
BP	GO:0048762	mesenchymal cell differentiation	40/2112	219/18670	0.001499	0.01153	0.00833	KITLG/SFRP1/EPHA3/BMP4/LRP6/SEMA4A/DLG5/STAT1/SOX9/SEMA4D/FOXC1/SEMA3A/PPP2CA/BMPR1A/SIX2/HTR2B/PDPN/DAG1/TGFBR3/TMEM100/HGF/EZH2/LEF1/FAM172A/SEMA3F/SMAD3/LDLRAD4/NOTCH1/HEY2/ACVR1/EDNRB/TGFB3/WWTR1/IL6/CFL1/SEMA4F/SEMA3E/HEY1/SEMA6B/IL1B	40
BP	GO:0048568	embryonic organ development	69/2112	428/18670	0.001525	0.01171	0.008463	KITLG/BMP4/LRP6/CDKN1C/ZIC1/SOX9/GLI3/FOXC1/ZFPM2/SIX1/BMPR1A/SIX2/COBL/SHOX2/YAP1/GATA2/TUBB2B/EGFR/ADA/SOBP/KMT2A/E2F8/BPTF/CXCL8/SPINT2/TCF7/HOXC4/ID3/CHST11/SOD1/PBX1/EFEMP1/LEF1/HYAL1/SMAD3/RBP4/IRX5/NOTCH1/PAX5/ZFP36L1/ARNT/HEY2/TFAP2A/HOXA4/ACVR1/FGF9/HOXD10/TGFB3/KRT19/NIPBL/TULP3/FZD6/MEGF8/CEBPA/SH2B3/HIPK2/HEY1/KDR/SYF2/PKD2/DVL1/MYO3A/ERCC1/HOXA11/FZD2/TP53/HOXA5/STIL/AHI1	69
BP	GO:0032733	positive regulation of interleukin-10 production	11/2112	36/18670	0.001541	0.01179	0.00852	XCL1/SASH3/TLR2/IRF4/LGALS9/NOD2/CLEC7A/HGF/CD40LG/CD83/SYK	11
BP	GO:0046627	negative regulation of insulin receptor signaling pathway	11/2112	36/18670	0.001541	0.01179	0.00852	ENPP1/PID1/PTPRE/PRKCQ/PRKCB/PTPN2/SOCS1/CISH/SOCS2/KANK1/IL1B	11
BP	GO:0090322	regulation of superoxide metabolic process	11/2112	36/18670	0.001541	0.01179	0.00852	GCH1/ITGB2/CD36/EGFR/FBLN5/CLEC7A/SOD1/RGN/SYK/FPR2/CYBA	11
BP	GO:0001916	positive regulation of T cell mediated cytotoxicity	9/2112	26/18670	0.001544	0.0118	0.008524	XCL1/PTPRC/HLA-F/HLA-A/HLA-C/HLA-G/HLA-E/HLA-B/FAM49B	9
BP	GO:0034446	substrate adhesion-dependent cell spreading	22/2112	100/18670	0.001579	0.01202	0.008685	GBP1/ITGB7/ITGA4/ANTXR1/AXL/ITGB1BP1/FERMT2/PDPN/DOCK1/PARVA/FZD4/EFNA5/FZD7/MYOC/KANK1/FER/AP1AR/FBLN1/AKIP1/MERTK/ITGAV/LIMS2	22
BP	GO:0010762	regulation of fibroblast migration	10/2112	31/18670	0.001582	0.01202	0.008685	DDR2/ITGB1BP1/FGF2/AKAP12/C5orf30/SLC8A1/PAK1/ARHGAP4/FER/PRR5L	10
BP	GO:0034694	response to prostaglandin	10/2112	31/18670	0.001582	0.01202	0.008685	SFRP1/CCL19/AKR1C3/CCR7/TGFBR3/CCL21/PTGFR/PTGER4/P2RY6/P2RY4	10
BP	GO:0045648	positive regulation of erythrocyte differentiation	10/2112	31/18670	0.001582	0.01202	0.008685	STAT1/INHBA/GATA2/NCKAP1L/ARNT/TRIM58/INPP5D/FOXO3/PRMT1/ISG15	10
BP	GO:2000406	positive regulation of T cell migration	10/2112	31/18670	0.001582	0.01202	0.008685	CCL5/CXCL13/XCL1/CCR2/ITGA4/ADAM8/TNFRSF14/CXCL10/CCL21/ADAM10	10
BP	GO:0031663	lipopolysaccharide-mediated signaling pathway	15/2112	58/18670	0.001589	0.01204	0.008701	CCL5/TNFAIP3/TLR2/MALT1/CD36/RIPK2/NFKBIA/CD6/PTPN22/CD180/IL18/LYN/HCK/CCL2/IL1B	15
BP	GO:0061900	glial cell activation	15/2112	58/18670	0.001589	0.01204	0.008701	PTPRC/CLU/TLR8/CST7/TLR2/ITGB2/JAK2/CTSC/EGFR/SPHK1/IFNG/IL6/FPR2/TLR6/IL1B	15
BP	GO:0031032	actomyosin structure organization	37/2112	199/18670	0.001594	0.01206	0.008716	PIK3R1/SFRP1/EPB41L2/LIMCH1/MYH10/TMOD1/LPAR1/PFN2/ITGB1BP1/DLC1/CDC42BPA/TAC1/WAS/NOX4/ARHGEF10/SMAD3/CORO2B/TNFAIP1/GPR65/RACGAP1/MYOC/ECT2/LMOD1/PPM1F/PTGER4/PAK1/SORBS1/TGFB3/KRT19/AKAP13/MYH11/WASF2/WDR1/CFLAR/S1PR1/PFN1/KIF23	37
BP	GO:1902749	regulation of cell cycle G2/M phase transition	39/2112	213/18670	0.001627	0.01227	0.008864	PSMB9/PSMB8/PSMB10/DTL/CETN2/SKP1/HMMR/PLK1/TPX2/TUBA4A/PSME1/CDC14B/BLM/CDC25B/FHL1/SMARCD3/CDK1/CEP135/TUBB4A/PBX1/NEK2/BRD4/DONSON/CDC7/CCNB1/MECP2/CCND1/FBXO5/CNTRL/CENPF/MIIP/AURKB/CEP63/FBXL7/SYF2/NAE1/TP53/AURKA/TOPBP1	39
BP	GO:0010819	regulation of T cell chemotaxis	7/2112	17/18670	0.001631	0.01227	0.008864	CCL5/CXCL13/XCL1/CCR2/CXCL10/CCL21/ADAM10	7
BP	GO:0032740	positive regulation of interleukin-17 production	7/2112	17/18670	0.001631	0.01227	0.008864	PRKCQ/IL15/MYD88/NOD2/SPHK1/IL6/IL18	7
BP	GO:0035855	megakaryocyte development	7/2112	17/18670	0.001631	0.01227	0.008864	FLI1/MEIS1/PTPN6/PTPN11/PIP4K2A/SH2B3/WASF2	7
BP	GO:1902931	negative regulation of alcohol biosynthetic process	7/2112	17/18670	0.001631	0.01227	0.008864	PLEK/ERLIN1/SOD1/NFKB1/ERLIN2/GFI1/DKK3	7
BP	GO:0050769	positive regulation of neurogenesis	75/2112	474/18670	0.00165	0.01239	0.008954	NDNF/EPHA3/CCR2/GDF5/S100A9/BMP4/NAP1L2/PRKCH/TNFRSF1B/DLG5/ASPM/CXCR4/SEMA4D/GLI3/NTRK2/SEMA3A/CDON/LPAR1/ZNF365/TLR2/PTPRD/ITSN1/TIMP2/COBL/SHOX2/GATA2/MMD/TUBB2B/DAG1/ETV5/TRPV2/ASPA/SMARCD3/CREB3L2/HGF/MAGI2/NLGN1/EZH2/CX3CR1/SOCS2/SCARF1/CAMK1D/PTN/FZD4/EFNA5/SCN1B/NOTCH1/FEZ1/ECT2/GDI1/NBL1/IL6ST/SERPINI1/IFNG/SYT17/PAK1/DPYSL3/NIPBL/SCARB2/IL6/CHODL/MAP1B/MEGF8/PRKD1/LYN/DVL1/KIF20B/TENM4/CFLAR/FEZF2/GDPD5/SH3GL3/IL1B/ACTR2/BRINP1	75
BP	GO:0048545	response to steroid hormone	63/2112	385/18670	0.001652	0.0124	0.008959	SFRP1/BMP4/CDO1/RBFOX2/LMO3/AKR1C3/TLR2/AR/PAM/KANK2/ICAM1/JAK2/ANXA3/YAP1/EGFR/NPC1/TAF7/UFSP2/PGRMC2/PCK1/PTN/TP63/PMEPA1/PAPPA/LEF1/FOXO1/CA2/NOTCH1/ARNTL/ZFP36L1/SSTR5/CSN1S1/ATP1A2/OR51E2/FLT3/ALPL/PAK1/ADIPOQ/CCND1/FOSL1/PARP1/TGFB3/CALCOCO1/IL6/AKAP13/MAOB/CD38/TYMS/NR1H3/FOXO3/RB1/CYBA/TFPI/IL1RN/RWDD1/ABCA3/IGFBP2/CFLAR/ZFP36L2/ALAD/NRIP1/RNF14/THRA	63
BP	GO:0070169	positive regulation of biomineral tissue development	13/2112	47/18670	0.001657	0.0124	0.008961	NELL1/BMP4/BMPR1A/PTN/SMAD3/KL/SLC8A1/TFAP2A/ACVR1/FBXO5/TGFB3/ATRAID/ISG15	13
BP	GO:0070231	T cell apoptotic process	13/2112	47/18670	0.001657	0.0124	0.008961	CCL5/BMP4/IDO1/PRKCQ/IL7R/GLI3/LGALS9/ADAM8/ADA/BAK1/CD27/IL2RA/TP53	13
BP	GO:0002831	regulation of response to biotic stimulus	28/2112	139/18670	0.001677	0.01254	0.009058	TRAF3/AIM2/TNFAIP3/BIRC3/STAT1/IL15/APOBEC3G/HTRA1/CD36/MICB/RIPK2/CRTAM/TSPAN6/CD160/CD226/DDX58/HERC5/DDX60/CD180/TRIM38/CXCL6/CYBA/NOD1/SPINK5/IL2RA/IL1B/MMP12/LILRB1	28
BP	GO:0031647	regulation of protein stability	49/2112	284/18670	0.001714	0.0128	0.00925	PIK3R1/IGF1/CLU/PIM1/ANK2/PFN2/CRYAB/TNIP2/PLK1/TRIM24/UBE2B/CHFR/USP3/CREBBP/DPM3/CRTAP/BAG2/ZNF207/ASPH/CCDC88C/ATP1B1/TRIM21/SMAD3/MYLIP/HSP90AB1/DACT1/PEX19/STXBP1/PINK1/PER3/TESC/NLK/LMNA/CDC37L1/PRKD1/DVL1/CD81/BAG5/GOLGA7/AFM/PFN1/TP53/USP7/PIM2/CAMLG/AURKA/GSN/TBL1X/CTSH	49
BP	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	58/2112	349/18670	0.001719	0.01282	0.009262	SFRP1/GDF5/BMP4/FMOD/CDKN1C/LTBP3/SKI/INHBA/PARD3/ARHGEF18/HTRA1/SULF1/FERMT2/CILP/LTBP2/BMPR1A/ADAMTSL2/NUP93/COMP/TWSG1/TGFBR3/CREBBP/TMEM100/MAGI2/NEO1/GLG1/CHST11/PMEPA1/LEF1/SMAD3/LDLRAD4/UBE2D1/NOTCH1/NBL1/TOB1/CHRDL1/HSP90AB1/ACVR1/FGF9/PARP1/HFE/TGFB3/WWTR1/TTK/MEGF8/NLK/FST/FERMT1/HIPK2/FSTL3/DKK3/FUT8/ZNF8/LRRC32/TP53/SPTBN1/CDH5/PML	58
BP	GO:0055123	digestive system development	29/2112	146/18670	0.001754	0.01299	0.009383	SFRP1/BMP4/CDKN1C/GLI3/WLS/SIX2/COBL/SHOX2/EGFR/ADA/YIPF6/CXCL8/TCF7/TP63/DCHS1/SMAD3/NOTCH1/CCNB1/DACT1/EDNRB/FGF9/TGFB3/NIPBL/MEGF8/FAT4/TYMS/RB1/HOXA5/AHI1	29
BP	GO:0000212	meiotic spindle organization	6/2112	13/18670	0.001762	0.01299	0.009383	ASPM/GOLGA2/ATRX/FBXO5/TUBG2/AURKA	6
BP	GO:0009650	UV protection	6/2112	13/18670	0.001762	0.01299	0.009383	SCARA3/MFAP4/FEN1/SDF4/CAT/ERCC1	6
BP	GO:0010745	negative regulation of macrophage derived foam cell differentiation	6/2112	13/18670	0.001762	0.01299	0.009383	ABCG1/NFKBIA/ADIPOQ/CETP/NR1H3/ITGAV	6
BP	GO:0014842	regulation of skeletal muscle satellite cell proliferation	6/2112	13/18670	0.001762	0.01299	0.009383	ANGPT1/SIX1/JAK2/FGF2/EPHB1/CFLAR	6
BP	GO:0021554	optic nerve development	6/2112	13/18670	0.001762	0.01299	0.009383	GLI3/LPAR1/TCIRG1/RPL24/EPHB1/NAV2	6
BP	GO:0030656	regulation of vitamin metabolic process	6/2112	13/18670	0.001762	0.01299	0.009383	AKR1C3/NFKB1/IFNG/GFI1/CD320/IL1B	6
BP	GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production	6/2112	13/18670	0.001762	0.01299	0.009383	RASGRP1/DDX58/SYK/CD80/IL18/IL1B	6
BP	GO:0045779	negative regulation of bone resorption	6/2112	13/18670	0.001762	0.01299	0.009383	TNFAIP3/TNFRSF11B/CSK/IL6/CD38/INPP5D	6
BP	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading	6/2112	13/18670	0.001762	0.01299	0.009383	GBP1/ITGB1BP1/EFNA5/KANK1/AP1AR/FBLN1	6
BP	GO:0007409	axonogenesis	74/2112	468/18670	0.001797	0.01323	0.009557	PIK3R1/EPHA3/BCL11B/UCHL1/SEMA4A/RAC2/MYH10/CXCR4/NDN/PRKCQ/ITGA4/SEMA4D/GLI3/NTRK2/TSKU/SEMA3A/RAB8A/PARD3/AUTS2/LAMA2/TRAK2/COBL/SHOX2/TUBB2B/DAG1/KLF7/NFIB/RPL24/FGF13/TRPV2/ERBB2/NEO1/ENAH/EPHB1/AFG3L2/PIK3CD/CDH2/UNC5C/RYK/PTPRS/TCTN1/SEMA3F/CYFIP2/EFNA5/VASP/PTPN11/CHN1/SCN1B/NOTCH1/FEZ1/GDI1/PIK3CA/HSP90AB1/PAK1/STXBP1/CTTN/B3GNT2/CHODL/MAP1B/LGI1/ARHGAP4/MEGF8/DPYSL2/SEMA4F/SEMA3E/GAB2/GFRA2/DVL1/SEMA6B/FEZ2/FEZF2/SPTBN1/DCLK1/CHL1	74
BP	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	22/2112	101/18670	0.001807	0.01329	0.009599	CTSF/CD74/DYNC1LI2/CTSL/KIF11/KIF15/HLA-DRA/KIF3B/HLA-DPB1/SEC31A/KIF2C/KIF4A/DYNC1I1/HLA-DMA/HLA-DMB/RACGAP1/HLA-DQB2/DCTN6/HLA-DPA1/CAPZA1/OSBPL1A/KIF23	22
BP	GO:0002639	positive regulation of immunoglobulin production	12/2112	42/18670	0.001825	0.01336	0.009653	XCL1/PTPRC/SASH3/IL4R/CD40/TFRC/HLA-E/TBX21/RBP4/STX4/TNFRSF4/IL6	12
BP	GO:0006509	membrane protein ectodomain proteolysis	12/2112	42/18670	0.001825	0.01336	0.009653	TIMP3/TNFRSF1B/PRKCQ/ADAM19/TIMP4/ADAM8/TIMP2/DAG1/IFNG/BACE1/ADAM10/IL1B	12
BP	GO:0017145	stem cell division	12/2112	42/18670	0.001825	0.01336	0.009653	NAP1L2/ASPM/ZBTB16/SOX5/EVI2B/ETV5/FGF13/LEF1/FZD7/NOTCH1/WWTR1/ZFP36L2	12
BP	GO:0005996	monosaccharide metabolic process	50/2112	292/18670	0.001826	0.01336	0.009653	ENPP1/IGF1/GALT/NPY1R/CHST15/NFE2L1/PTPN2/OAS1/AKR1B1/HK3/CYB5R3/ALDOC/PC/PASK/SIK1/PCK1/PER2/LRP5/COX11/ACACB/RPIA/FAM3C/SLC2A3/PMAIP1/PGD/FOXO1/RBP4/LEP/PPP1CA/RGN/PIK3CA/FUCA1/ADIPOQ/FABP5/PDK4/SORBS1/MDH1/FGGY/UGT2B17/MAN2B1/SLC23A2/GSTO1/MAN2A2/FUT8/TP53/TALDO1/SLC35A2/TKTL1/FUT4/ALDH5A1	50
BP	GO:0031330	negative regulation of cellular catabolic process	46/2112	264/18670	0.001904	0.01389	0.01004	LAMP3/NELL1/TIMP3/MYD88/TIMP4/CBFA2T3/RASIP1/GOLGA2/HDAC4/TIMP2/HTR2B/HNRNPA0/GABARAPL2/DAP/NPC1/HGF/ACACB/DAZL/FEZ1/LEP/TOB1/RGN/PIK3CA/HSP90AB1/IL10RA/HFE/PINK1/MAPKAPK2/PTPN22/HP/UBE2J1/NBAS/HIPK2/BAG5/ALAD/FEZ2/MTMR2/WAC/PBK/ATRAID/TP53/USP7/CAMLG/PARN/UBE2G2/PML	46
BP	GO:0010518	positive regulation of phospholipase activity	15/2112	59/18670	0.001912	0.01389	0.01004	CCL5/ITK/ARL1/NTRK2/LPAR1/HTR2B/EGFR/FGF2/SELE/TXK/HTR2A/AGTR1/P2RY6/ANG/S1PR4	15
BP	GO:0033619	membrane protein proteolysis	15/2112	59/18670	0.001912	0.01389	0.01004	TIMP3/TNFRSF1B/PRKCQ/ADAM19/TIMP4/ADAM8/TIMP2/DAG1/NFKB1/IFNG/BACE1/ADAM10/MBTPS2/IL1B/CTSH	15
BP	GO:0045071	negative regulation of viral genome replication	15/2112	59/18670	0.001912	0.01389	0.01004	CCL5/SLPI/APOBEC3G/OAS1/ISG20/SRPK1/OASL/FAM111A/MPHOSPH8/OAS3/IFIT5/PLSCR1/MX1/ZC3HAV1/ISG15	15
BP	GO:0045824	negative regulation of innate immune response	15/2112	59/18670	0.001912	0.01389	0.01004	SLAMF8/TNFAIP3/HLA-F/PTPN2/HLA-G/LGALS9/NMI/CD96/TRAFD1/HLA-E/CR1/ADAR/NR1H3/MMP12/LILRB1	15
BP	GO:0070527	platelet aggregation	15/2112	59/18670	0.001912	0.01389	0.01004	PRKCQ/HBB/COMP/PDPN/PTPN6/PLEK/CD9/SYK/STXBP1/HSPB1/PRKG1/MYL9/LYN/SH2B3/GP1BA	15
BP	GO:0032465	regulation of cytokinesis	20/2112	89/18670	0.001929	0.014	0.01012	CETN2/PLK1/CDC14B/E2F8/CDC25B/KIF3B/MAP9/PRC1/CSPP1/KIF20A/PLK2/RACGAP1/ECT2/SSTR5/KLHL9/AURKB/KLHL21/KIF20B/AURKA/KIF23	20
BP	GO:0033209	tumor necrosis factor-mediated signaling pathway	32/2112	167/18670	0.001936	0.01404	0.01014	TRAF3/AIM2/PSMB9/TNFAIP3/PSMB8/TNFRSF11B/BIRC3/TNFRSF1B/STAT1/TRAF1/PSMB10/PTPN2/LTB/JAK2/CD40/CDIP1/TNFRSF14/PSME1/SPHK1/CD27/NFKBIA/CD40LG/CASP1/ADIPOQ/SYK/IKBKG/TNFRSF4/FOXO3/CLIP3/TNFRSF9/CASP4/TNFRSF17	32
BP	GO:0033622	integrin activation	8/2112	22/18670	0.001961	0.01416	0.01023	CXCL13/ITGB1BP1/RASIP1/FERMT2/PLEK/SKAP1/PTGER4/COL16A1	8
BP	GO:0045624	positive regulation of T-helper cell differentiation	8/2112	22/18670	0.001961	0.01416	0.01023	CCL19/IL4R/MALT1/RIPK2/CD86/CD80/IL18/NLRP3	8
BP	GO:1904666	regulation of ubiquitin protein ligase activity	8/2112	22/18670	0.001961	0.01416	0.01023	UBE2C/MAD2L1/GOLGA2/PLK1/CDC14B/BAG2/FBXO5/CDC20	8
BP	GO:0030212	hyaluronan metabolic process	11/2112	37/18670	0.001972	0.0142	0.01026	IL15/PIM1/HMMR/FGF2/LYVE1/ITIH5/HGF/NFKB1/HYAL1/STAB2/IL1B	11
BP	GO:2000403	positive regulation of lymphocyte migration	11/2112	37/18670	0.001972	0.0142	0.01026	CCL5/CXCL13/XCL1/CCR2/ITGA4/ADAM8/TNFRSF14/CXCL10/CCL21/CCL7/ADAM10	11
BP	GO:0006275	regulation of DNA replication	23/2112	108/18670	0.001972	0.0142	0.01026	NUCKS1/PPP2CA/ZNF365/TTF1/EGFR/BLM/E2F8/ZBTB38/CDK1/CCNA2/STAG2/TSPYL2/ID3/RFC3/ATRX/TNFAIP1/DONSON/TIMELESS/CDC7/TERF1/DBF4/FBXO5/TP53	23
BP	GO:0060828	regulation of canonical Wnt signaling pathway	49/2112	286/18670	0.001991	0.01432	0.01034	PSMB9/SFRP1/PSMB8/LRP6/GPC5/WNT5B/ASPM/RBMS3/PSMB10/SOX9/GLI3/IGFBP6/WLS/ZBED2/YAP1/PSME1/EGFR/UBE2B/RECK/TCF7L2/SOX2/CDH2/PLEKHA4/NFKB1/FOXO1/CDK14/SMAD3/FZD7/DAAM2/NOTCH1/ARNTL/VCP/KANK1/PPP1CA/DACT1/FGF9/WWTR1/FZD6/DDIT3/FOXO3/FERMT1/IGFBP2/RNF146/DVL1/DKK3/NLE1/FRAT1/NPHP4/TBL1X	49
BP	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	17/2112	71/18670	0.001999	0.01434	0.01036	CCL5/CRLF1/IGF1/IL15/HCLS1/JAK2/CD40/GHR/LEP/IL6ST/IFNG/PECAM1/FLT3/CTF1/IL6/IL18/LYN	17
BP	GO:0048565	digestive tract development	27/2112	134/18670	0.002	0.01434	0.01036	SFRP1/BMP4/GLI3/SIX2/COBL/SHOX2/EGFR/ADA/YIPF6/CXCL8/TCF7/TP63/DCHS1/SMAD3/NOTCH1/CCNB1/DACT1/EDNRB/FGF9/TGFB3/NIPBL/MEGF8/FAT4/TYMS/RB1/HOXA5/AHI1	27
BP	GO:0006732	coenzyme metabolic process	65/2112	403/18670	0.002027	0.01452	0.01049	BHMT2/IGF1/NT5E/GCH1/IDO1/ZBTB20/FMO2/KYNU/SLC2A6/CBFA2T3/PMVK/PCBD1/NUP93/HDAC4/HK3/CYB5R3/MTHFD2/ALDOC/PC/MCCC1/MPC2/IDH2/TPR/AHCYL1/ACAT1/NUP160/ACACB/RPIA/SLC2A3/HTR2A/PGD/MOCS2/PCCA/HSD17B12/SUCLA2/MAT1A/VCP/IFNG/ARNT/KMO/RGN/MBIP/PDK4/AHCYL2/NDUFA9/MDH1/CD38/ELOVL4/TYMS/MPC1/FOLH1/SLC23A2/NUP88/ELOVL2/GSTO1/AASS/ACSM5/ACSM3/NUP50/TP53/ACSL5/SLC5A6/TALDO1/ELOVL5/GPD1L	65
BP	GO:0001774	microglial cell activation	13/2112	48/18670	0.002041	0.01454	0.0105	PTPRC/CLU/TLR8/CST7/TLR2/ITGB2/JAK2/CTSC/SPHK1/IFNG/IL6/FPR2/TLR6	13
BP	GO:0002269	leukocyte activation involved in inflammatory response	13/2112	48/18670	0.002041	0.01454	0.0105	PTPRC/CLU/TLR8/CST7/TLR2/ITGB2/JAK2/CTSC/SPHK1/IFNG/IL6/FPR2/TLR6	13
BP	GO:0002762	negative regulation of myeloid leukocyte differentiation	13/2112	48/18670	0.002041	0.01454	0.0105	PIK3R1/SFRP1/INHBA/PTPN2/LILRB3/GATA2/LILRB4/ADIPOQ/INPP5D/LYN/FSTL3/TOB2/LILRB1	13
BP	GO:0035272	exocrine system development	13/2112	48/18670	0.002041	0.01454	0.0105	SOX9/FOXC1/SEMA3A/FGF7/WLS/TWSG1/EGFR/DAG1/NFIB/HGF/IGSF3/TGFB3/TGM2	13
BP	GO:0090199	regulation of release of cytochrome c from mitochondria	13/2112	48/18670	0.002041	0.01454	0.0105	IGF1/CLU/BID/TNFSF10/BAK1/HGF/PMAIP1/FAM162A/HIGD1A/PINK1/LMNA/TP53/MOAP1	13
BP	GO:0009895	negative regulation of catabolic process	52/2112	308/18670	0.002051	0.01459	0.01054	LAMP3/NELL1/TIMP3/MYD88/TIMP4/CBFA2T3/RASIP1/DYSF/MAD2L1/GOLGA2/HDAC4/TIMP2/HTR2B/HNRNPA0/EGFR/GABARAPL2/DAP/NPC1/HGF/ACACB/DAZL/SMAD3/FEZ1/LEP/TOB1/RGN/PIK3CA/HSP90AB1/IL10RA/HFE/PINK1/MAPKAPK2/PTPN22/HP/UBE2J1/NBAS/PDE3B/HIPK2/BAG5/ALAD/FEZ2/MTMR2/WAC/PBK/ATRAID/TP53/USP7/CAMLG/IL1B/PARN/UBE2G2/PML	52
BP	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	22/2112	102/18670	0.002063	0.01463	0.01057	CTSF/CD74/DYNC1LI2/CTSL/KIF11/KIF15/HLA-DRA/KIF3B/HLA-DPB1/SEC31A/KIF2C/KIF4A/DYNC1I1/HLA-DMA/HLA-DMB/RACGAP1/HLA-DQB2/DCTN6/HLA-DPA1/CAPZA1/OSBPL1A/KIF23	22
BP	GO:0010522	regulation of calcium ion transport into cytosol	22/2112	102/18670	0.002063	0.01463	0.01057	CXCL9/XCL1/CORO1A/SRI/ANK2/CXCL10/PTPN6/BAK1/PLN/TRPC1/CD19/ATP1A2/CXCL11/SLC8A1/P2RY6/APLNR/CYBA/LYN/PKD2/GSTO1/GSTM2/PML	22
BP	GO:0035335	peptidyl-tyrosine dephosphorylation	22/2112	102/18670	0.002063	0.01463	0.01057	PTPRC/PTPN14/EYA4/PTPRE/DUSP5/PTPN2/EYA2/PTPRD/PTPN7/CDC14B/PTPN6/CDC25B/MTMR14/PTPRF/PTPRS/PTPN11/PTPN13/PTPN22/DUSP6/SSH3/DUSP2/MTMR2	22
BP	GO:0060325	face morphogenesis	10/2112	32/18670	0.002071	0.01467	0.0106	PLEKHA1/LRP6/SKI/SGPL1/ASPH/RRAS/LEF1/PTPN11/TGFB3/NIPBL	10
BP	GO:0040013	negative regulation of locomotion	64/2112	396/18670	0.002078	0.0147	0.01062	CXCL13/SLAMF8/SFRP1/IGFBP5/IL27RA/LIMCH1/SEMA4A/DLG5/ARHGDIB/ARPIN/SEMA4D/SEMA3A/MCTP1/CD200/CD74/PTPN2/PFN2/ITGB1BP1/SULF1/BMPR1A/WASL/RECK/ADA/DAG1/DLC1/FGF2/GPR18/DCN/ADORA3/IDH2/CCL21/WAS/SPINT2/MAGI2/CX3CR1/PTN/RYK/C5orf30/RRAS/TRIM21/SEMA3F/LDLRAD4/NOTCH1/KANK1/NBL1/RGN/MECP2/PTGER4/ADIPOQ/DPYSL3/ARHGAP4/PRKG1/SEMA4F/MIIP/FOXO3/AP1AR/FBLN1/SEMA3E/TRIM26/ABHD6/SEMA6B/CCL2/PML/SCAI	64
BP	GO:0072207	metanephric epithelium development	9/2112	27/18670	0.002086	0.01472	0.01064	STAT1/SOX9/YAP1/ACAT1/ADIPOQ/WWTR1/FAT4/PKD2/POU3F3	9
BP	GO:1901623	regulation of lymphocyte chemotaxis	9/2112	27/18670	0.002086	0.01472	0.01064	CCL5/CXCL13/XCL1/CCR2/CXCL10/CCL21/CCL7/ADAM10/CCL2	9
BP	GO:0045444	fat cell differentiation	40/2112	223/18670	0.002117	0.01493	0.01078	ENPP1/FTO/SFRP1/PSMB8/WNT5B/LMO3/ZBTB16/SH2B2/RUNX1T1/ALDH6A1/CBY1/ZFPM2/DYSF/PLAC8/SOCS1/GATA2/AAMDC/ADIRF/TCF7L2/PER2/LRP5/HTR2A/FOXO1/SMAD3/ARNTL/LEP/ZFP36L1/ADIPOQ/CCND1/NIPBL/WWTR1/IL6/ARL4A/DDIT3/SDF4/FABP4/CLIP3/CEBPA/ZFP36L2/WIF1	40
BP	GO:0051494	negative regulation of cytoskeleton organization	29/2112	148/18670	0.002174	0.01531	0.01106	CORO1A/ADD3/ARPIN/TMOD1/PFN2/TMSB10/CKAP2/DLC1/FGF13/WAS/TUBB4A/GMFG/NEK2/CORO2B/MYOC/KANK1/LMOD1/CAMSAP2/MAP1B/CAPZA1/VILL/CLIP3/WASF2/S1PR1/CCNF/PFN1/SPTBN1/GSN/CDH5	29
BP	GO:1904645	response to amyloid-beta	14/2112	54/18670	0.002192	0.01542	0.01114	IGF1/ITGA4/CACNA2D1/ICAM1/CD36/DNM1/BCL2L2/PARP1/BACE1/FOXO3/FPR2/CASP4/TLR6/MMP12	14
BP	GO:0030010	establishment of cell polarity	27/2112	135/18670	0.002236	0.01571	0.01135	CCL19/CYTH1/PARD3/CCR7/JAM3/MAP4/NDC80/MAD2L1/PLK1/AMOTL2/FGF13/CCL21/EPHB1/MCPH1/DOCK2/FEZ1/KANK1/HSP90AB1/PAK1/MAP1B/CFL1/FERMT1/MPP5/KIF20B/RAB11FIP2/GSN/CDH5	27
BP	GO:1905477	positive regulation of protein localization to membrane	25/2112	122/18670	0.002262	0.01587	0.01147	PIK3R1/EPHA3/TFDP2/PRKCH/GZMB/BID/ITGB1BP1/ITGB2/EGFR/ERBB2/PTN/TP63/PMAIP1/RHOG/IFNG/PAK1/MYO1C/STX4/SORBS1/CLIP3/TP53BP2/CD81/RAB11FIP2/TP53/SPTBN1	25
BP	GO:0010863	positive regulation of phospholipase C activity	12/2112	43/18670	0.002275	0.0159	0.01149	ITK/NTRK2/LPAR1/HTR2B/EGFR/FGF2/SELE/TXK/HTR2A/P2RY6/ANG/S1PR4	12
BP	GO:0050850	positive regulation of calcium-mediated signaling	12/2112	43/18670	0.002275	0.0159	0.01149	CD3E/IGF1/TRAT1/ADA/ZAP70/SYK/P2RY6/PKD2/GSTO1/GSTM2/CAMTA1/HINT1	12
BP	GO:1904646	cellular response to amyloid-beta	12/2112	43/18670	0.002275	0.0159	0.01149	IGF1/ITGA4/CACNA2D1/ICAM1/CD36/BCL2L2/PARP1/BACE1/FOXO3/FPR2/CASP4/TLR6	12
BP	GO:1903829	positive regulation of cellular protein localization	54/2112	324/18670	0.002276	0.0159	0.01149	PIK3R1/EPHA3/EPB41L2/TFDP2/ZIC1/PRKCH/CD247/RAC2/GLI3/GZMB/BID/HCLS1/ITGB1BP1/ITGB2/NDC80/PLK1/EGFR/TPR/ERBB2/CDK1/TCF7L2/PTN/TP63/ZPR1/PMAIP1/SMAD3/EDEM1/ECT2/LEP/RHOG/IFNG/HSP90AB1/PAK1/MYO1C/STX4/ZFAND1/SORBS1/PARP1/VAMP2/NIPBL/PINK1/CLIP3/HSPA1L/KIF20B/TP53BP2/CD81/EDEM2/PRR5L/RAB11FIP2/TP53/SPTBN1/IL1B/XPO4/GPD1L	54
BP	GO:0060420	regulation of heart growth	19/2112	84/18670	0.002283	0.01593	0.01151	IGF1/PIM1/MEIS1/ZFPM2/BMPR1A/YAP1/FGF2/TGFBR3/CDK1/KCNK2/ACACB/RBP4/NOTCH1/CCNB1/HEY2/PAK1/FGF9/DUSP6/JARID2	19
BP	GO:0007266	Rho protein signal transduction	37/2112	203/18670	0.002287	0.01594	0.01152	RAC2/ARHGDIB/ARHGEF18/LPAR1/RHOBTB3/RASIP1/KANK2/ARHGEF9/ARHGEF26/ITSN1/RHOF/PDPN/DLC1/GPR18/WAS/CDC42EP3/RHOH/ARHGEF3/ARHGEF10/ARHGEF12/NET1/VAV1/TNFAIP1/GPR65/MYOC/ECT2/KANK1/RHOG/AGTR1/PECAM1/RHOD/AKAP13/ARHGAP4/CFL1/GPR4/VAV3/SCAI	37
BP	GO:0046474	glycerophospholipid biosynthetic process	39/2112	217/18670	0.002302	0.01603	0.01158	PLA2G2D/PLEKHA1/CPNE3/PIK3R1/PIGK/CHPT1/PIP4K2B/HTR2B/FGF2/SH3YL1/DPM3/PLCG2/GPAA1/PLD1/MTMR14/ETNK1/PLA2G12A/PIK3CD/PIGH/PLEKHA4/HTR2A/PTPN13/DGKA/PIK3CA/PIGP/FABP5/PLEKHA2/PIK3R3/INPP5D/PTDSS1/PLSCR1/PIP4K2A/FPR2/STARD7/PIGT/PIGF/MTMR2/RAB14/GPD1L	39
BP	GO:0031960	response to corticosteroid	31/2112	162/18670	0.002306	0.01604	0.01159	CDO1/AKR1C3/PAM/ICAM1/ANXA3/EGFR/PCK1/PAPPA/FOXO1/NOTCH1/ZFP36L1/SSTR5/CSN1S1/FLT3/ALPL/ADIPOQ/CCND1/FOSL1/PARP1/IL6/AKAP13/MAOB/TYMS/FOXO3/CYBA/IL1RN/ABCA3/IGFBP2/CFLAR/ZFP36L2/ALAD	31
BP	GO:0042246	tissue regeneration	18/2112	78/18670	0.002327	0.01616	0.01168	IGF1/PPP3CA/SGCA/DYSF/YAP1/DAG1/EZH2/SOX2/PTN/FZD7/CD9/NOTCH1/CCNB1/CPQ/TEC/CD81/CFLAR/GSN	18
BP	GO:0038094	Fc-gamma receptor signaling pathway	28/2112	142/18670	0.002331	0.01617	0.01169	PIK3R1/PTPRC/CD247/CD3G/WASL/FGR/PLCG2/WAS/CLEC4E/DOCK1/NCKAP1L/CYFIP2/VAV1/IGLC1/IGLV1-44/PIK3CA/HSP90AB1/PAK1/MYO1C/SYK/IGHG1/LYN/HCK/ARPC1A/WASF2/ACTR3/VAV3/ACTR2	28
BP	GO:0002532	production of molecular mediator involved in inflammatory response	17/2112	72/18670	0.002347	0.01625	0.01174	SLAMF8/IDO1/MYD88/IL4R/NOD2/CD36/CD96/GPSM3/CLEC7A/C5orf30/CD6/LEP/SYK/BTK/LYN/TLR6/ALOX5	17
BP	GO:0061035	regulation of cartilage development	17/2112	72/18670	0.002347	0.01625	0.01174	GDF5/BMP4/TRPS1/PTHLH/FGF18/SOX9/ZBTB16/GLI3/LTBP3/SOX5/SIX2/SHOX2/GLG1/EFEMP1/SMAD3/LEP/HOXA11	17
BP	GO:0001911	negative regulation of leukocyte mediated cytotoxicity	7/2112	18/18670	0.00241	0.01661	0.012	PTPRC/HLA-F/IL7R/HLA-G/LGALS9/HLA-E/LILRB1	7
BP	GO:0051023	regulation of immunoglobulin secretion	7/2112	18/18670	0.00241	0.01661	0.012	CD40/HLA-E/CD40LG/RBP4/STX4/TNFRSF4/IL6	7
BP	GO:0070233	negative regulation of T cell apoptotic process	7/2112	18/18670	0.00241	0.01661	0.012	CCL5/BMP4/IDO1/PRKCQ/IL7R/ADA/CD27	7
BP	GO:0090330	regulation of platelet aggregation	7/2112	18/18670	0.00241	0.01661	0.012	PRKCQ/PDPN/CD9/SYK/PRKG1/LYN/SH2B3	7
BP	GO:0010771	negative regulation of cell morphogenesis involved in differentiation	21/2112	97/18670	0.002454	0.0169	0.01221	GBP1/SEMA4A/SEMA4D/SEMA3A/PPP3CA/ITGB1BP1/TRAK2/FGF13/NLGN1/RYK/PTPRS/SEMA3F/EFNA5/GDI1/KANK1/ARHGAP4/SEMA4F/AP1AR/FBLN1/SEMA3E/SEMA6B	21
BP	GO:0051271	negative regulation of cellular component movement	62/2112	384/18670	0.002472	0.017	0.01228	CXCL13/SLAMF8/SFRP1/IGFBP5/IL27RA/LIMCH1/SEMA4A/DLG5/ARHGDIB/ARPIN/SEMA4D/SEMA3A/MCTP1/CD200/CD74/PFN2/ITGB1BP1/SULF1/BMPR1A/WASL/RECK/ADA/DAG1/DLC1/FGF2/TGFBR3/GPR18/DCN/ADORA3/IDH2/CCL21/WAS/SPINT2/MAGI2/CX3CR1/PTN/RYK/C5orf30/RRAS/SEMA3F/LDLRAD4/CD9/NOTCH1/KANK1/NBL1/RGN/MECP2/PTGER4/ADIPOQ/DPYSL3/ARHGAP4/PRKG1/SEMA4F/MIIP/FOXO3/AP1AR/FBLN1/SEMA3E/ABHD6/SEMA6B/CCL2/SCAI	62
BP	GO:0048546	digestive tract morphogenesis	13/2112	49/18670	0.002495	0.017	0.01228	SFRP1/BMP4/GLI3/SIX2/SHOX2/EGFR/TCF7/TP63/SMAD3/NOTCH1/DACT1/NIPBL/AHI1	13
BP	GO:0060042	retina morphogenesis in camera-type eye	13/2112	49/18670	0.002495	0.017	0.01228	LRP6/SOX9/CDON/PTN/LRP5/RBP4/IRX5/TFAP2A/ZHX2/HIPK2/DIO3/ROM1/AHI1	13
BP	GO:0016572	histone phosphorylation	11/2112	38/18670	0.002496	0.017	0.01228	PRKCB/VRK1/JAK2/UBE2B/CDK1/CCNA2/RPS6KA4/CCNB1/AURKB/AURKA/IL1B	11
BP	GO:0032620	interleukin-17 production	11/2112	38/18670	0.002496	0.017	0.01228	IL27RA/RFTN1/PRKCQ/IL15/MYD88/NOD2/SPHK1/NCKAP1L/IFNG/IL6/IL18	11
BP	GO:0046636	negative regulation of alpha-beta T cell activation	11/2112	38/18670	0.002496	0.017	0.01228	XCL1/RUNX3/GLI3/IL4R/LGALS9/TNFRSF14/SOCS1/TWSG1/TBX21/HFE/LILRB1	11
BP	GO:0060045	positive regulation of cardiac muscle cell proliferation	11/2112	38/18670	0.002496	0.017	0.01228	PIM1/ZFPM2/BMPR1A/YAP1/FGF2/TGFBR3/CDK1/NOTCH1/CCNB1/HEY2/FGF9	11
BP	GO:1900077	negative regulation of cellular response to insulin stimulus	11/2112	38/18670	0.002496	0.017	0.01228	ENPP1/PID1/PTPRE/PRKCQ/PRKCB/PTPN2/SOCS1/CISH/SOCS2/KANK1/IL1B	11
BP	GO:1904037	positive regulation of epithelial cell apoptotic process	11/2112	38/18670	0.002496	0.017	0.01228	ITGA4/AKR1C3/HLA-G/JAK2/CD40/CD160/CD40LG/IL6/FOXO3/CCL2/GSN	11
BP	GO:0035265	organ growth	37/2112	204/18670	0.002496	0.017	0.01228	IGF1/SCARA3/DDR2/SOX9/PIM1/FOXC1/MEIS1/SASH3/FGF7/AR/ZFPM2/COCH/BMPR1A/COMP/YAP1/FGF2/TGFBR3/COL14A1/CDK1/KCNK2/SORBS2/PDLIM5/SOD1/ACACB/PTPN11/RBP4/NOTCH1/LEP/CCNB1/HEY2/PAK1/FGF9/AKAP13/DUSP6/JARID2/TENM4/S1PR1	37
BP	GO:0051928	positive regulation of calcium ion transport	25/2112	123/18670	0.002541	0.01728	0.01249	CCL5/CXCL9/XCL1/SRI/CACNA2D1/ANK2/CXCL10/TRPV2/PLCG2/BAK1/CCR1/TRPC1/CD19/ATP1B1/RGN/CXCL11/FGF14/P2RY6/APLNR/PKD2/GSTO1/MYLK/GSTM2/CCL2/CASK	25
BP	GO:0051170	import into nucleus	31/2112	163/18670	0.002546	0.0173	0.0125	PIK3R1/BMP4/ZIC1/GLI3/PPP3CA/ANGPT1/HCLS1/CD36/NUP93/SIX2/TPR/NFKBIA/ZPR1/SMAD3/ARNTL/ECT2/LEP/IFNG/SYK/FGF9/SNRPB/IPO7/KPNA2/LMNA/FERMT1/NUP88/NUP50/TP53/HEATR3/MMP12/PML	31
BP	GO:0070997	neuron death	57/2112	348/18670	0.002612	0.01773	0.01281	CCL5/NDNF/CRLF1/GDF5/CORO1A/CLU/HLA-F/NQO1/TNFRSF1B/NTRK2/CD200/ANGPT1/BID/AXL/SIGMAR1/ITGB2/OXR1/MAP3K11/SIX1/ADAM8/JAK2/HDAC4/ITSN1/LANCL1/CX3CR1/EPHB1/TP63/SOD1/ZPR1/FAM162A/IFNG/KMO/PIK3CA/MECP2/TFAP2A/HSP90AB1/PARP1/IKBKG/STXBP1/TGFB3/PINK1/BACE1/APAF1/DDIT3/FOXO3/RB1/TRIM2/HIPK2/DIO3/PIGT/TP53BP2/BAG5/NAE1/TP53/CCL2/TLR6/CHL1	57
BP	GO:0014031	mesenchymal cell development	19/2112	85/18670	0.002635	0.01786	0.0129	KITLG/BMP4/SEMA4A/SOX9/SEMA4D/FOXC1/SEMA3A/BMPR1A/HTR2B/FAM172A/SEMA3F/NOTCH1/HEY2/ACVR1/EDNRB/CFL1/SEMA4F/SEMA3E/SEMA6B	19
BP	GO:0042306	regulation of protein import into nucleus	14/2112	55/18670	0.00264	0.01786	0.0129	PIK3R1/BMP4/ZIC1/GLI3/ANGPT1/HCLS1/CD36/TPR/ZPR1/SMAD3/ECT2/LEP/IFNG/FERMT1	14
BP	GO:0043113	receptor clustering	14/2112	55/18670	0.00264	0.01786	0.0129	ITGB7/ITGA4/GLRB/ITGB1BP1/ITGB2/ETV5/ITGAL/MAGI2/NLGN1/PTN/CDH2/DVL1/CD81/GSN	14
BP	GO:0010876	lipid localization	64/2112	400/18670	0.002653	0.01793	0.01295	ENPP1/PLA2G2D/FTO/LRP6/CLU/APOL1/SERPINA5/INHBA/ABCG1/PTPN2/SIGMAR1/ABCC4/APOL6/AQP9/DYSF/CD36/APOL3/ATP8B2/ATP8A1/ATP9A/AKR1C1/NPC1/TAC1/GULP1/NMB/NFKBIA/PLA2G12A/ACACB/NFKB1/FZD4/ABCA8/PTPN11/RBP4/LIPG/LEP/STARD5/AGTR1/ADIPOQ/SYK/LRP10/CETP/MEST/PITPNC1/SCARB2/IL6/HDLBP/NR1H3/OSBPL1A/FABP4/STARD7/SLC27A5/APOLD1/OSBPL9/ABCA3/NME4/REN/SLCO1C1/UGCG/LIPC/ITGAV/STOML1/NRIP1/IL1B/SOAT2	64
BP	GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	22/2112	104/18670	0.002667	0.018	0.01301	GDF5/BMP4/CDKN1C/INHBA/SULF1/BMPR1A/NUP93/TWSG1/TGFBR3/CREBBP/NEO1/NOTCH1/HSP90AB1/ACVR1/FGF9/PARP1/HFE/TGFB3/TTK/FERMT1/HIPK2/CDH5	22
BP	GO:0033028	myeloid cell apoptotic process	10/2112	33/18670	0.002675	0.018	0.01301	CCL5/KITLG/CCR5/NOD2/IRF7/CTSL/PIK3CD/ADIPOQ/IL6/THRA	10
BP	GO:0070232	regulation of T cell apoptotic process	10/2112	33/18670	0.002675	0.018	0.01301	CCL5/BMP4/IDO1/PRKCQ/IL7R/LGALS9/ADAM8/ADA/CD27/TP53	10
BP	GO:0048754	branching morphogenesis of an epithelial tube	29/2112	150/18670	0.002676	0.018	0.01301	BMP4/LRP6/DLG5/SOX9/GLI3/RASIP1/AR/SIX1/SIX2/YAP1/DAG1/FGF2/ETV5/LRP5/PBX1/DCHS1/LEF1/NOTCH1/TIMELESS/PPP1CA/PAK1/ACVR1/FAT4/SEMA3E/PKD2/HOXA11/HOXA5/PML/CTSH	29
BP	GO:0034695	response to prostaglandin E	8/2112	23/18670	0.002712	0.01816	0.01312	SFRP1/CCL19/CCR7/TGFBR3/CCL21/PTGER4/P2RY6/P2RY4	8
BP	GO:0048714	positive regulation of oligodendrocyte differentiation	8/2112	23/18670	0.002712	0.01816	0.01312	TNFRSF1B/CXCR4/ZNF365/TLR2/DAG1/ASPA/PTN/TENM4	8
BP	GO:0072170	metanephric tubule development	8/2112	23/18670	0.002712	0.01816	0.01312	STAT1/SOX9/YAP1/ACAT1/WWTR1/FAT4/PKD2/POU3F3	8
BP	GO:0097150	neuronal stem cell population maintenance	8/2112	23/18670	0.002712	0.01816	0.01312	ASPM/SOX2/CDH2/MCPH1/FOXO1/NOTCH1/FOXO3/SS18	8
BP	GO:0060537	muscle tissue development	65/2112	408/18670	0.002743	0.01831	0.01323	SGCB/BMP4/IGFBP5/IGF1/MYH10/HLF/SOX9/PIM1/FOXC1/SKI/PPP3CA/CDON/MEIS1/HIVEP3/CBY1/ZFPM2/EYA2/SIX1/BMPR1A/HDAC4/SHOX2/YAP1/FGF2/TGFBR3/DCN/CDK1/SIK1/KCNK2/SORBS2/PLN/EPHB1/PDLIM5/NOX4/SGCD/PITX1/LEF1/SMAD3/FZD7/RBP4/NOTCH1/ARNTL/PAX5/CCNB1/HEY2/SLC8A1/PAK1/POPDC2/ACVR1/FGF9/HOXD10/CENPF/AKAP13/JARID2/MYH11/LMNA/RB1/PKD2/KCNAB1/MYLK/GJC1/TENM4/CFLAR/MYL6B/S1PR1/ALPK3	65
BP	GO:0000281	mitotic cytokinesis	17/2112	73/18670	0.002743	0.01831	0.01323	MYH10/NUSAP1/PLK1/CKAP2/CEP55/MAP9/KIF4A/KIF20A/RACGAP1/ECT2/CHMP2B/CFL1/KIF20B/ARL3/SPTBN1/CHMP1B/KIF23	17
BP	GO:0006801	superoxide metabolic process	17/2112	73/18670	0.002743	0.01831	0.01323	GCH1/NQO1/ITGB2/CD36/EGFR/FBLN5/SH3PXD2A/CLEC7A/CYB5R4/NCF4/NOX4/SOD1/RGN/SYK/FPR2/CYBA/NCF1	17
BP	GO:0007411	axon guidance	47/2112	276/18670	0.002745	0.01831	0.01323	PIK3R1/EPHA3/BCL11B/SEMA4A/RAC2/MYH10/CXCR4/PRKCQ/SEMA4D/GLI3/SEMA3A/LAMA2/TUBB2B/DAG1/KLF7/NFIB/RPL24/ERBB2/NEO1/ENAH/EPHB1/PIK3CD/UNC5C/RYK/SEMA3F/CYFIP2/EFNA5/VASP/PTPN11/CHN1/SCN1B/FEZ1/PIK3CA/B3GNT2/LGI1/MEGF8/DPYSL2/SEMA4F/SEMA3E/GAB2/GFRA2/DVL1/SEMA6B/FEZ2/FEZF2/SPTBN1/CHL1	47
BP	GO:0002691	regulation of cellular extravasation	9/2112	28/18670	0.002769	0.01843	0.01332	CCR2/IL27RA/ITGA4/ICAM1/ADAM8/PDGFD/CCL21/PTGER4/IL1R1	9
BP	GO:0032647	regulation of interferon-alpha production	9/2112	28/18670	0.002769	0.01843	0.01332	TLR8/STAT1/IRF7/NMI/IFIH1/RIPK2/DDX58/PTPRS/MMP12	9
BP	GO:0007100	mitotic centrosome separation	6/2112	14/18670	0.00279	0.01847	0.01335	KIF11/KIF3B/MAP9/NEK2/CEP85/AURKA	6
BP	GO:0014841	skeletal muscle satellite cell proliferation	6/2112	14/18670	0.00279	0.01847	0.01335	ANGPT1/SIX1/JAK2/FGF2/EPHB1/CFLAR	6
BP	GO:0014857	regulation of skeletal muscle cell proliferation	6/2112	14/18670	0.00279	0.01847	0.01335	ANGPT1/SIX1/JAK2/FGF2/EPHB1/CFLAR	6
BP	GO:0030207	chondroitin sulfate catabolic process	6/2112	14/18670	0.00279	0.01847	0.01335	DCN/BGN/CSPG4/VCAN/HYAL1/IDUA	6
BP	GO:0035112	genitalia morphogenesis	6/2112	14/18670	0.00279	0.01847	0.01335	LRP6/AR/TCF7/TP63/RBP4/NIPBL	6
BP	GO:0030225	macrophage differentiation	12/2112	44/18670	0.002811	0.01855	0.0134	BMP4/IL15/INHBA/TLR2/PTPN2/HCLS1/GATA2/ADIPOQ/PARP1/SPI1/RB1/CEBPA	12
BP	GO:0050654	chondroitin sulfate proteoglycan metabolic process	12/2112	44/18670	0.002811	0.01855	0.0134	NDNF/SPOCK2/CHST15/CHST3/DCN/BGN/CSPG4/CHST11/VCAN/HYAL1/UGDH/IDUA	12
BP	GO:2000404	regulation of T cell migration	12/2112	44/18670	0.002811	0.01855	0.0134	CCL5/CXCL13/XCL1/CCR2/IL27RA/ITGA4/CD200/ADAM8/TNFRSF14/CXCL10/CCL21/ADAM10	12
BP	GO:0034504	protein localization to nucleus	45/2112	262/18670	0.002818	0.01858	0.01342	PIK3R1/BMP4/ZIC1/GBP2/SOX9/ZBTB16/GLI3/PPP3CA/SKP1/ANGPT1/HCLS1/SIX1/PLK1/CD36/NUP93/SIX2/TPR/BARD1/CDK1/LILRB4/NFKBIA/ZPR1/SMAD3/MFHAS1/TOR1AIP1/ARNTL/ECT2/LEP/IFNG/SYK/FGF9/PARP1/PAF1/IPO7/KPNA2/LMNA/FERMT1/NUP88/DVL1/NUP50/TP53/HEATR3/MMP12/PML/DCLK1	45
BP	GO:0001667	ameboidal-type cell migration	72/2112	461/18670	0.002828	0.01862	0.01345	CXCL13/KITLG/BMP4/SEMA4A/DDR2/ITGB7/ARHGDIB/FGF18/SOX9/ITGA4/SEMA4D/SEMA3A/EMP2/ANGPT1/FGF7/PFN2/MAPRE2/ITGB1BP1/ITGB2/KANK2/SGPL1/CD40/PRKD2/ANXA3/HTR2B/SCG2/GATA2/AMOTL2/TNS1/HBEGF/FGF2/DCN/TAC1/AKAP12/SP1/PTN/DOCK1/C5orf30/SEMA3F/HYAL1/PTPN11/PLK2/NOTCH1/KANK1/IFNG/PECAM1/PIK3CA/MECP2/SLC8A1/PPM1F/PAK1/ACVR1/EDNRB/HSPB1/PIK3R3/AKT3/ARHGAP4/MEGF8/FER/CFL1/SEMA4F/FERMT1/SEMA3E/PRKD1/KDR/WASF2/SEMA6B/CAPN7/PRR5L/PFN1/PML/CTSH	72
BP	GO:0001558	regulation of cell growth	66/2112	416/18670	0.002831	0.01862	0.01345	ENPP1/CDKN2C/SFRP1/S100A9/IGFBP5/IGF1/SEMA4A/PLCE1/CXCR4/PRKCQ/SIPA1/SEMA4D/SEMA3A/INHBA/PPP2CA/CHPT1/SPOCK1/KAZALD1/CRLF3/CRYAB/NDRG3/RPS6KA1/CISH/EGFR/FBLN5/HBEGF/SPHK1/FHL1/FGF13/TRPV2/ERBB2/SOCS2/CLSTN1/TSPYL2/NDUFA13/RYK/PTPRS/LEF1/SEMA3F/NET1/HYAL1/EFNA5/SMAD3/SMARCA2/GDI1/AGTR1/SYT17/PAK1/CTTN/MAP1B/LGI1/ARHGAP4/CD38/MEGF8/BCL11A/DPYSL2/SEMA4F/RB1/CYBA/SEMA3E/ADAM10/SEMA6B/TP53/DCBLD2/EAF2/PML	66
BP	GO:0001768	establishment of T cell polarity	5/2112	10/18670	0.002845	0.01862	0.01345	CCL19/CCR7/CCL21/DOCK2/GSN	5
BP	GO:0032926	negative regulation of activin receptor signaling pathway	5/2112	10/18670	0.002845	0.01862	0.01345	SKI/MAGI2/ACVR1/FST/FSTL3	5
BP	GO:0034135	regulation of toll-like receptor 2 signaling pathway	5/2112	10/18670	0.002845	0.01862	0.01345	TNFAIP3/MFHAS1/CYBA/LYN/TLR6	5
BP	GO:0051231	spindle elongation	5/2112	10/18670	0.002845	0.01862	0.01345	KIF4A/PRC1/RACGAP1/AURKB/KIF23	5
BP	GO:0072610	interleukin-12 secretion	5/2112	10/18670	0.002845	0.01862	0.01345	TLR8/CCL19/CCR7/LGALS9/LILRB1	5
BP	GO:0000910	cytokinesis	32/2112	171/18670	0.002856	0.01867	0.01349	MYH10/CETN2/NUSAP1/PLK1/CKAP2/CDC14B/E2F8/CDC25B/CEP55/KIF3B/MAP9/KIF4A/PRC1/CSPP1/KIF20A/PLK2/RACGAP1/ECT2/SSTR5/KLHL9/CHMP2B/CFL1/AURKB/KLHL21/KIF20B/ARL3/ACTR3/AURKA/SPTBN1/ACTR2/CHMP1B/KIF23	32
BP	GO:0010975	regulation of neuron projection development	77/2112	499/18670	0.002859	0.01867	0.01349	NDNF/SFRP1/EPHA3/S100A9/SEMA4A/DLG5/CXCR4/SEMA4D/NTRK2/SEMA3A/PPP3CA/SPOCK1/LPAR1/ZNF365/GAK/PTPRD/TRAK2/ITSN1/COBL/SHOX2/TUBB2B/PMP22/FGF13/TRPV2/CREB3L2/HGF/MAGI2/NLGN1/EZH2/SCARF1/CAMK1D/PTPRF/PTN/PDLIM5/CDH2/RYK/PTPRS/FZD4/SEMA3F/EFNA5/CHN1/PLK2/SCN1B/FEZ1/GDI1/KANK1/SERPINI1/MYLIP/SYT17/PAK1/DPYSL3/GFI1/CAMSAP2/CTTN/SCARB2/MARK1/CHODL/MAP1B/ARHGAP4/CD38/MEGF8/BCL11A/DPYSL2/CFL1/SEMA4F/SEMA3E/ADAM10/CDC20/PRKD1/LYN/DVL1/BAG5/CFLAR/SEMA6B/ABI2/FEZF2/ACTR2	77
BP	GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	42/2112	241/18670	0.002906	0.01895	0.01369	SFRP1/GDF5/BMP4/CDKN1C/SKI/INHBA/HTRA1/SULF1/CILP/BMPR1A/ADAMTSL2/NUP93/TWSG1/TGFBR3/CREBBP/MAGI2/NEO1/GLG1/CHST11/PMEPA1/SMAD3/LDLRAD4/NOTCH1/NBL1/TOB1/CHRDL1/HSP90AB1/ACVR1/FGF9/PARP1/HFE/TGFB3/WWTR1/TTK/FST/FERMT1/HIPK2/FSTL3/DKK3/TP53/SPTBN1/CDH5	42
BP	GO:0007369	gastrulation	34/2112	185/18670	0.002925	0.01906	0.01377	SFRP1/BMP4/LRP6/ITGA4/FOXC1/INHBA/ITGB2/EYA2/BMPR1A/WLS/SIX2/TWSG1/DAG1/COL8A1/SOX2/LRP5/LEF1/SMAD3/FZD7/UGDH/KIF16B/ADIPOQ/ACVR1/APLNR/PAF1/EXT2/MEGF8/IL1RN/SYF2/DVL1/TENM4/HOXA11/ITGAV/TP53	34
BP	GO:0043112	receptor metabolic process	35/2112	192/18670	0.002946	0.01917	0.01385	TBC1D16/TRAT1/ANGPT1/TBC1D5/ITGB2/USP46/ACKR3/JAK2/CD36/HTR2B/DNM1/TFRC/CXCL8/SELE/PLCG2/MAGI2/LRPAP1/GPRASP1/CD9/KIF16B/MYLIP/IFNG/ADIPOQ/SYK/NR1H3/AP1AR/CD81/FUT8/ATXN2/MTMR2/ITGAV/CAMLG/HOXA5/LILRB1/AHI1	35
BP	GO:0097485	neuron projection guidance	47/2112	277/18670	0.002952	0.0192	0.01387	PIK3R1/EPHA3/BCL11B/SEMA4A/RAC2/MYH10/CXCR4/PRKCQ/SEMA4D/GLI3/SEMA3A/LAMA2/TUBB2B/DAG1/KLF7/NFIB/RPL24/ERBB2/NEO1/ENAH/EPHB1/PIK3CD/UNC5C/RYK/SEMA3F/CYFIP2/EFNA5/VASP/PTPN11/CHN1/SCN1B/FEZ1/PIK3CA/B3GNT2/LGI1/MEGF8/DPYSL2/SEMA4F/SEMA3E/GAB2/GFRA2/DVL1/SEMA6B/FEZ2/FEZF2/SPTBN1/CHL1	47
BP	GO:0010498	proteasomal protein catabolic process	74/2112	477/18670	0.002971	0.0193	0.01394	LAMP3/PSMB9/UCHL1/PSMB8/CLU/PSMB10/PTTG1/NFE2L1/SKP1/AREL1/UBE2C/CBFA2T3/MAD2L1/PLK1/PSME1/UBE2B/GABARAPL2/CHFR/IFI27/SPOP/CDK1/BAG2/ERLIN1/TBX21/BUB1B/RHBDF1/PPP2CB/PMAIP1/EDEM1/PCNP/TNFAIP1/PLK2/UBE2D1/FBXL2/ARNTL/VCP/CCNB1/SOCS6/HSP90AB1/ERLIN2/FBXO5/HFE/CRBN/PINK1/WWTR1/CUL2/TRIM38/SDF2L1/RCN3/RNF19B/DDIT3/AURKB/UBE2J1/TRIM2/CDC20/CUL4B/CEBPA/FBXL7/DVL1/BAG5/EDEM2/KCTD5/ALAD/CCNF/WAC/PBK/USP7/CAMLG/AURKA/RNF14/TBL1X/UBE2G2/PML/KCTD2	74
BP	GO:0010171	body morphogenesis	13/2112	50/18670	0.003028	0.0196	0.01416	PLEKHA1/MAB21L2/LRP6/SKI/CDON/SGPL1/DAG1/ASPH/RRAS/LEF1/PTPN11/TGFB3/NIPBL	13
BP	GO:0010718	positive regulation of epithelial to mesenchymal transition	13/2112	50/18670	0.003028	0.0196	0.01416	BMP4/FOXC1/PDPN/TCF7L2/EZH2/LEF1/SMAD3/NOTCH1/ACVR1/TGFB3/WWTR1/IL6/IL1B	13
BP	GO:0070671	response to interleukin-12	13/2112	50/18670	0.003028	0.0196	0.01416	LCP1/LMNB1/JAK2/RIPK2/STAT4/HNRNPDL/SOD1/IFNG/CFL1/CAPZA1/GSTO1/TALDO1/TYK2	13
BP	GO:0071375	cellular response to peptide hormone stimulus	53/2112	321/18670	0.003042	0.01967	0.01421	ENPP1/PID1/PIK3R1/CSK/STAT1/PTPRE/PRKCQ/SH2B2/NUCKS1/RAB8A/PRKCB/PTPN2/TCIRG1/JAK2/SOCS1/CISH/CPEB1/GHR/AHCYL1/SP1/CCNA2/SOCS2/PCK1/ZNF106/NFKB1/FOXO1/PTPN11/CA2/KL/KANK1/LEP/ZFP36L1/AGTR1/PIK3CA/PRL/PAK1/MYO1C/ADIPOQ/PDK4/SORBS1/PARP1/VAMP2/PIK3R3/MAP1B/FER/FOXO3/CYBA/LYN/PDE3B/CFLAR/IRS4/ATP6V1B2/IL1B	53
BP	GO:0048713	regulation of oligodendrocyte differentiation	11/2112	39/18670	0.003126	0.0202	0.01459	TNFRSF1B/CXCR4/ZNF365/TLR2/DAG1/ASPA/PTN/DAAM2/NOTCH1/TENM4/WDR1	11
BP	GO:2001235	positive regulation of apoptotic signaling pathway	33/2112	179/18670	0.003173	0.02048	0.0148	LCK/SFRP1/PTPRC/S100A9/TFDP2/TIMP3/SERINC3/TPD52L1/INHBA/GZMB/BID/PTPN2/TNFSF10/LGALS9/JAK2/CTSC/BAK1/TP63/SOD1/PMAIP1/SMAD3/FAM162A/PPP1CA/PINK1/APAF1/G0S2/DDIT3/TP53BP2/TP53/MOAP1/GSN/PML/CTSH	33
BP	GO:0051054	positive regulation of DNA metabolic process	40/2112	228/18670	0.00319	0.02057	0.01486	PTPRC/EYA4/PRKCQ/EYA2/CD40/PRKD2/ANXA3/TFRC/EGFR/UBE2B/FGF2/E2F8/WAS/CDK1/HGF/TBX21/NOX4/NEK7/RFC3/NEK2/DNMT1/ATRX/TNFAIP1/TIMELESS/CDC7/MECP2/MPHOSPH8/HSP90AB1/DBF4/PARP1/IL6/AURKB/ERCC1/SETMAR/SMCHD1/USP7/PARM1/PARN/ACTR2/PML	40
BP	GO:1990748	cellular detoxification	23/2112	112/18670	0.003222	0.02075	0.015	S100A9/GCH1/NQO1/LTC4S/GSTM3/HBB/CD36/FBLN5/ESD/SOD1/GPX3/IPCEF1/GPX4/HBD/RGN/PRDX6/PTGS1/ADH5/HP/SESN1/GSTO1/CAT/GSTM2	23
BP	GO:0019915	lipid storage	16/2112	68/18670	0.003229	0.02076	0.015	ENPP1/FTO/ABCG1/PTPN2/DYSF/CD36/NFKBIA/ACACB/NFKB1/LEP/MEST/IL6/NR1H3/ITGAV/NRIP1/IL1B	16
BP	GO:0050918	positive chemotaxis	16/2112	68/18670	0.003229	0.02076	0.015	CCL5/BMP4/CORO1A/ANGPT1/FGF7/SCG2/CXCL10/FGF2/CXCL8/HGF/SMAD3/IL16/FPR2/VEGFB/KDR/S1PR1	16
BP	GO:0048704	embryonic skeletal system morphogenesis	20/2112	93/18670	0.003333	0.0214	0.01546	BMP4/GLI3/SIX1/SIX2/SHOX2/HOXC4/CHST11/HYAL1/SMAD3/IRX5/PAX5/TFAP2A/HOXA4/HOXD10/TGFB3/NIPBL/TULP3/MEGF8/HOXA11/HOXA5	20
BP	GO:0002440	production of molecular mediator of immune response	48/2112	286/18670	0.00335	0.02148	0.01552	XCL1/PTPRC/CCR2/IL27RA/HLA-F/TNFRSF1B/IL7R/TRDV3/BATF/SASH3/TLR2/ANGPT1/CD74/TCIRG1/IL4R/HLA-G/NOD2/MALT1/CD36/CD96/CD40/TNFRSF14/TFRC/HLA-E/CD160/CD226/TBX21/IL13RA2/CD40LG/DDX58/RBP4/IGLV1-44/DDX1/STX4/HFE/TGFB3/BTK/TNFRSF4/IL6/IL18/CD81/ERCC1/SPINK5/THOC1/IL1R1/IL1B/LILRB1/NLRP3	48
BP	GO:0002244	hematopoietic progenitor cell differentiation	31/2112	166/18670	0.003398	0.02177	0.01573	PSMB9/KITLG/SFRP1/PTPRC/BMP4/PSMB8/PSMB10/BATF/FOXC1/INHBA/JAM3/EML1/PRRC2C/YAP1/GATA2/PSME1/MEOX1/PTPN6/KMT2A/PLEK/TOP2A/C12orf29/NOTCH1/ADAR/FLT3/HERC6/MLF1/SPI1/FST/FSTL3/TP53	31
BP	GO:0032392	DNA geometric change	24/2112	119/18670	0.003401	0.02177	0.01573	PURA/CETN2/CHD1/CDC45/BLM/SMARCA1/MCM5/RFC3/TOP2A/GINS1/ATRX/NAV2/MCM2/DDX1/CHD4/PARP1/ACTR8/MCM4/CUL4B/ERCC6L/HMGA1/CHD9/TP53/GTF2H5	24
BP	GO:0032660	regulation of interleukin-17 production	10/2112	34/18670	0.003411	0.02181	0.01576	IL27RA/PRKCQ/IL15/MYD88/NOD2/SPHK1/NCKAP1L/IFNG/IL6/IL18	10
BP	GO:0002433	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis	27/2112	139/18670	0.003434	0.02188	0.01581	PIK3R1/PTPRC/CD247/CD3G/WASL/FGR/PLCG2/WAS/DOCK1/NCKAP1L/CYFIP2/VAV1/IGLC1/IGLV1-44/PIK3CA/HSP90AB1/PAK1/MYO1C/SYK/IGHG1/LYN/HCK/ARPC1A/WASF2/ACTR3/VAV3/ACTR2	27
BP	GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	27/2112	139/18670	0.003434	0.02188	0.01581	PIK3R1/PTPRC/CD247/CD3G/WASL/FGR/PLCG2/WAS/DOCK1/NCKAP1L/CYFIP2/VAV1/IGLC1/IGLV1-44/PIK3CA/HSP90AB1/PAK1/MYO1C/SYK/IGHG1/LYN/HCK/ARPC1A/WASF2/ACTR3/VAV3/ACTR2	27
BP	GO:1900274	regulation of phospholipase C activity	12/2112	45/18670	0.003446	0.02188	0.01581	ITK/NTRK2/LPAR1/HTR2B/EGFR/FGF2/SELE/TXK/HTR2A/P2RY6/ANG/S1PR4	12
BP	GO:0010888	negative regulation of lipid storage	7/2112	19/18670	0.003447	0.02188	0.01581	ABCG1/PTPN2/NFKBIA/LEP/IL6/NR1H3/ITGAV	7
BP	GO:0032288	myelin assembly	7/2112	19/18670	0.003447	0.02188	0.01581	ANK2/TLR2/PMP22/CD9/MPP5/TENM4/MTMR2	7
BP	GO:0032930	positive regulation of superoxide anion generation	7/2112	19/18670	0.003447	0.02188	0.01581	ITGB2/EGFR/CLEC7A/SOD1/SYK/FPR2/CYBA	7
BP	GO:0045063	T-helper 1 cell differentiation	7/2112	19/18670	0.003447	0.02188	0.01581	RELB/SEMA4A/CCL19/IL4R/RIPK2/LEF1/CD80	7
BP	GO:0042542	response to hydrogen peroxide	28/2112	146/18670	0.003532	0.02237	0.01617	PLEKHA1/TNFAIP3/NQO1/STAT1/AXL/SIGMAR1/HBB/CRYAB/PDGFD/ADA/SPHK1/CDK1/BAK1/HGF/EZH2/SOD1/MAPK13/PPP2CB/FOXO1/NET1/ECT2/SLC8A1/FOSL1/PINK1/IL6/HP/FOXO3/CAT	28
BP	GO:2000241	regulation of reproductive process	28/2112	146/18670	0.003532	0.02237	0.01617	SFRP1/BMP4/IGF1/ASPM/ARHGDIB/SOX9/SEMA3A/INHBA/NPR2/AR/SULF1/ZFPM2/HDAC4/UBE2B/ADA/CDC25B/HPGDS/DAZL/NOTCH1/EDNRB/FBXO5/STXBP1/TTK/CDC20/OVGP1/TRIP13/EAF2/AURKA	28
BP	GO:0048706	embryonic skeletal system development	25/2112	126/18670	0.003557	0.02251	0.01626	BMP4/GLI3/SULF1/HOXC6/SIX1/SIX2/SHOX2/HOXC4/CHST11/PBX1/HYAL1/SMAD3/RBP4/IRX5/PAX5/TFAP2A/HOXA4/FGF9/HOXD10/TGFB3/NIPBL/TULP3/MEGF8/HOXA11/HOXA5	25
BP	GO:0034109	homotypic cell-cell adhesion	18/2112	81/18670	0.003601	0.02277	0.01645	CCL5/PRKCQ/HBB/COMP/PDPN/PTPN6/PLEK/CEACAM5/CD9/DSC2/SYK/STXBP1/HSPB1/PRKG1/MYL9/LYN/SH2B3/GP1BA	18
BP	GO:0090316	positive regulation of intracellular protein transport	29/2112	153/18670	0.003613	0.02282	0.01649	PIK3R1/ZIC1/RAC2/GLI3/HCLS1/ITGB1BP1/ITGB2/TPR/ERBB2/TCF7L2/ZPR1/SMAD3/EDEM1/ECT2/LEP/IFNG/PAK1/MYO1C/ZFAND1/VAMP2/PINK1/HSPA1L/KIF20B/CD81/EDEM2/PRR5L/TP53/IL1B/XPO4	29
BP	GO:0070229	negative regulation of lymphocyte apoptotic process	9/2112	29/18670	0.003618	0.02282	0.01649	CCL5/BMP4/IDO1/PRKCQ/IL7R/CD74/ADA/CD27/AURKB	9
BP	GO:0090102	cochlea development	13/2112	51/18670	0.003651	0.02301	0.01663	SOX9/SIX1/GATA2/SOBP/KCNK2/CCNA2/DCHS1/MCM2/HEY2/ADAM10/DVL1/MYO3A/FZD2	13
BP	GO:0031579	membrane raft organization	8/2112	24/18670	0.003669	0.02306	0.01666	PTPRC/CD2/RFTN1/EMP2/NPC1/FA2H/DOCK2/GSN	8
BP	GO:0033081	regulation of T cell differentiation in thymus	8/2112	24/18670	0.003669	0.02306	0.01666	BMP4/RASGRP1/IL7R/PTPN2/ADAM8/ADA/ERBB2/SOD1	8
BP	GO:2001026	regulation of endothelial cell chemotaxis	8/2112	24/18670	0.003669	0.02306	0.01666	CXCL13/FGF18/PRKD2/FGF2/NOTCH1/HSPB1/PRKD1/KDR	8
BP	GO:1903305	regulation of regulated secretory pathway	30/2112	160/18670	0.003679	0.0231	0.01669	CCR2/HLA-F/RAC2/PREPL/PRKCB/PFN2/ITGB2/IL4R/LGALS9/GATA2/FGR/NLGN1/IL13RA2/HTR2A/CHRNA5/RAB27A/NOTCH1/STXBP2/MICAL1/SYT17/STX4/SYK/STXBP1/BACE1/FER/GAB2/LYN/DVL1/CASK/P2RY4	30
BP	GO:0007050	cell cycle arrest	41/2112	237/18670	0.0037	0.0232	0.01676	CDKN2C/GAS1/CAB39L/IRF1/TFDP2/CDKN1C/INHBA/ZFHX3/CRLF3/CDC14B/EVI2B/E2F8/CXCL8/BARD1/CDK1/MAGI2/CGREF1/TCF7L2/SOX2/GAS7/MCPH1/SMAD3/PLK2/NOTCH1/IFNG/CCNB1/HSP90AB1/CCND1/MLF1/DDIT3/RB1/PKD2/KIF20B/PRMT1/SETMAR/PCBP4/TP53/PRKAB1/AURKA/PML/BRINP1	41
BP	GO:0043434	response to peptide hormone	68/2112	436/18670	0.00376	0.02351	0.01699	ENPP1/PID1/PIK3R1/IGFBP5/LRP6/CDO1/CSK/STAT1/PTPRE/PRKCQ/SH2B2/NUCKS1/RAB8A/PRKCB/TLR2/PTPN2/TNFSF10/TCIRG1/TIMP4/ICAM1/JAK2/SOCS1/CISH/CPEB1/STAT4/DAG1/TGFBR3/GHR/AHCYL1/SP1/CCNA2/SOCS2/PLN/PCK1/ZNF106/NFKB1/FOXO1/PTPN11/CA2/KL/KANK1/LEP/ZFP36L1/AGTR1/PIK3CA/PRL/PAK1/MYO1C/ADIPOQ/EDNRB/PDK4/SORBS1/PARP1/VAMP2/PIK3R3/MAP1B/FER/FOXO3/CYBA/LYN/PDE3B/CFLAR/CAT/HADH/IRS4/ATP6V1B2/IL1B/HADHA	68
BP	GO:0014888	striated muscle adaptation	14/2112	57/18670	0.003761	0.02351	0.01699	IGFBP5/IL15/PPP3CA/HDAC4/GTF2IRD2B/EZH2/FOXO1/SMAD3/MYOC/GTF2IRD1/HEY2/LMNA/CFLAR/GSN	14
BP	GO:0060760	positive regulation of response to cytokine stimulus	14/2112	57/18670	0.003761	0.02351	0.01699	CXCR4/TLR2/CD74/AXL/IRF7/IFIH1/RIPK2/TXK/DDX58/CASP1/GFI1/CASP4/IL1R1/MMP12	14
BP	GO:2001252	positive regulation of chromosome organization	32/2112	174/18670	0.003771	0.02355	0.01701	NAP1L2/PRKCQ/AUTS2/PRKD2/KMT2A/TPR/DLGAP5/NEK7/NEK2/RPS6KA4/FEN1/DNMT1/ATRX/BRD4/CCNB1/MECP2/MTF2/MPHOSPH8/TERF1/NIPBL/PAF1/PINK1/JARID2/LMNA/AURKB/RB1/PRKD1/ERCC1/TP53/IL1B/PARN/PML	32
BP	GO:0048511	rhythmic process	49/2112	295/18670	0.003775	0.02355	0.01702	RELB/PLEKHA1/HLF/DTL/NTRK2/INHBA/NFKB2/ZFHX3/AXL/TIMP4/PAM/SGPL1/EGFR/ADA/CREBBP/KMT2A/OPN3/CDK1/SIK1/SP1/NLGN1/EZH2/ID3/PER2/PTN/TOP2A/FZD4/BHLHE41/ARNTL/GFPT1/LEP/TIMELESS/PPP1CA/NFYA/ADIPOQ/PHLPP1/TGFB3/NDUFA9/HEBP1/PER3/TYMS/NR1H3/FOXO3/TP53/USP7/NRIP1/KDM2A/PTX3/PML	49
BP	GO:0006029	proteoglycan metabolic process	20/2112	94/18670	0.003794	0.02364	0.01708	NDNF/IGF1/SPOCK2/CHST15/SULF1/EXTL2/CHST3/DCN/BGN/CSPG4/TCF7L2/GAL3ST4/CHST11/VCAN/HYAL1/FAM20B/UGDH/IDUA/EXT2/CANT1	20
BP	GO:0072073	kidney epithelium development	27/2112	140/18670	0.003807	0.0237	0.01713	SFRP1/CRLF1/BMP4/STAT1/SOX9/GLI3/FOXC1/KANK2/SIX1/SIX2/YAP1/FGF2/MAGI2/ACAT1/PBX1/DCHS1/SMAD3/NOTCH1/PECAM1/ADIPOQ/WWTR1/FAT4/PKD2/CAT/POU3F3/HOXA11/AHI1	27
BP	GO:0043902	positive regulation of multi-organism process	34/2112	188/18670	0.003814	0.02373	0.01714	CCL5/PRF1/NUCKS1/INHBA/CD74/CHD1/LGALS9/HDAC4/RIPK2/PC/SRPK1/CLEC7A/CCNT1/SP1/TOP2A/LEF1/TRIM21/NOTCH1/GTF2F1/DDX60/IFNG/ADAR/SYK/POLR2L/EDNRB/CD180/TRIM38/CHMP2B/CFL1/KPNA2/RSF1/CYBA/NOD1/AURKA	34
BP	GO:0006575	cellular modified amino acid metabolic process	36/2112	202/18670	0.003818	0.02373	0.01714	PLA2G2D/BHMT2/GCH1/ALDH7A1/PCYOX1/SERINC3/LPCAT3/GSTM5/NFE2L1/GSTM3/GSTA4/DIO2/MTHFD2/CNDP2/CRTAP/AHCYL1/PLA2G12A/HPGDS/SOD1/GPX4/GLO1/P4HTM/CPQ/PLA1A/SERINC1/AHCYL2/TYMS/PTDSS1/PLSCR1/FOLH1/ACADL/HAGH/DIO3/GSTM2/SLC5A6/ALDH5A1	36
BP	GO:0062012	regulation of small molecule metabolic process	71/2112	459/18670	0.003829	0.02377	0.01718	ENPP1/PID1/PSMB9/PSMB8/IGF1/NQO1/ZBTB20/PSMB10/AKR1C3/ACADVL/ABCG1/NFE2L1/CD74/PTPN2/SLC2A6/CBFA2T3/COX7A1/PMVK/NUP93/HDAC4/PSME1/PASK/TPR/CDK1/PLEK/SIK1/ERLIN1/SP1/COX11/NUP160/SOD1/ACACB/FAM3C/NFKB1/PMAIP1/HTR2A/FOXO1/SC5D/HRH1/VCP/LEP/IFNG/ARNT/CCNB1/PPP1CA/RGN/NFYA/ADIPOQ/P2RY6/ERLIN2/FABP5/GFI1/PDK4/SORBS1/PARP1/SLC25A23/PINK1/CD320/NR1H3/GUCA1A/MBTPS2/ACADL/NUP88/DKK3/PTH1R/NUP50/TP53/IL1B/EPHX2/ELOVL5/COX7A2	71
BP	GO:0051341	regulation of oxidoreductase activity	22/2112	107/18670	0.003849	0.02387	0.01724	SLAMF8/GZMA/GCH1/NOD2/WASL/HTR2B/EGFR/DDAH2/NFKB1/LEP/AGTR1/IFNG/RGN/GFI1/ECSIT/HP/GLA/CYBA/NOD1/AOC3/NPR3/IL1B	22
BP	GO:0035690	cellular response to drug	59/2112	369/18670	0.003852	0.02387	0.01724	SLAMF8/AIM2/PLEKHA1/SFRP1/TNFAIP3/NQO1/CXCR4/SOX9/PPP3CA/AXL/SIGMAR1/ICAM1/NOD2/PDGFD/RIPK2/TFRC/EGFR/BLM/KMT2A/SPHK1/MAP4K1/CD69/CDK1/HGF/ADIRF/CCNA2/EZH2/PCK1/SOD1/MAPK13/NFKB1/FOXO1/NET1/EFNA5/ATRX/ECT2/TIMELESS/SLC8A1/PPM1F/CCL7/HSP90AB1/ADIPOQ/SPI1/PINK1/IL6/PTPN22/BCL11A/LDOC1/RYR3/FOXO3/CYBA/NOD1/KDR/CFLAR/REN/GSTM2/TP53/IL1B/P2RY4	59
BP	GO:0061351	neural precursor cell proliferation	28/2112	147/18670	0.003903	0.02416	0.01745	ASPM/GLI3/CDON/SOX5/EML1/GATA2/MELK/FGF13/SMARCD3/SPINT2/CX3CR1/EPHB1/PTN/CDH2/RYK/LEF1/FOXO1/DIXDC1/RACGAP1/NOTCH1/FZD6/FOXO3/EMX2/LYN/SHCBP1/POU3F3/TP53/LIMS2	28
BP	GO:0031532	actin cytoskeleton reorganization	21/2112	101/18670	0.004078	0.02522	0.01822	ARHGDIB/PDLIM4/EFS/ANTXR1/FGF7/AUTS2/HCLS1/CDC42BPA/PLEK/GMFG/PARVA/GPR65/PAK1/CTTN/RHOD/FER/SEMA3E/HCK/THSD7A/S1PR1/GSN	21
BP	GO:0008654	phospholipid biosynthetic process	44/2112	260/18670	0.004127	0.02549	0.01842	PLA2G2D/PLEKHA1/CPNE3/PIK3R1/PIGK/LPCAT3/CHPT1/PMVK/PIP4K2B/HTR2B/FGF2/SH3YL1/DPM3/PLCG2/GPAA1/PLD1/MTMR14/ETNK1/PLA2G12A/PIK3CD/PIGH/PLEKHA4/HTR2A/PTPN13/DGKA/PIK3CA/SERINC1/PIGP/FABP5/PLEKHA2/PIK3R3/SGMS1/INPP5D/PTDSS1/PLSCR1/PIP4K2A/FPR2/STARD7/PIGT/PIGF/MTMR2/MBOAT7/RAB14/GPD1L	44
BP	GO:0043523	regulation of neuron apoptotic process	37/2112	210/18670	0.004131	0.02549	0.01842	NDNF/CRLF1/GDF5/CORO1A/NQO1/NTRK2/ANGPT1/AXL/SIGMAR1/OXR1/MAP3K11/SIX1/ADAM8/JAK2/HDAC4/ITSN1/LANCL1/CX3CR1/SOD1/ZPR1/PIK3CA/MECP2/TFAP2A/HSP90AB1/PARP1/STXBP1/TGFB3/PINK1/BACE1/DDIT3/FOXO3/TRIM2/HIPK2/NAE1/TP53/CCL2/CHL1	37
BP	GO:0010883	regulation of lipid storage	12/2112	46/18670	0.004191	0.02572	0.01858	FTO/ABCG1/PTPN2/CD36/NFKBIA/ACACB/NFKB1/LEP/MEST/IL6/NR1H3/ITGAV	12
BP	GO:0048599	oocyte development	12/2112	46/18670	0.004191	0.02572	0.01858	IGF1/NPR2/CDC25B/DAZL/CCNB1/FBXO5/REC8/FOXO3/ANG/TRIP13/AURKA/YBX2	12
BP	GO:0002716	negative regulation of natural killer cell mediated immunity	6/2112	15/18670	0.004209	0.02572	0.01858	HLA-F/HLA-G/LGALS9/CD96/HLA-E/LILRB1	6
BP	GO:0014856	skeletal muscle cell proliferation	6/2112	15/18670	0.004209	0.02572	0.01858	ANGPT1/SIX1/JAK2/FGF2/EPHB1/CFLAR	6
BP	GO:0030852	regulation of granulocyte differentiation	6/2112	15/18670	0.004209	0.02572	0.01858	HCLS1/EVI2B/LEF1/ADIPOQ/INPP5D/TESC	6
BP	GO:0032645	regulation of granulocyte macrophage colony-stimulating factor production	6/2112	15/18670	0.004209	0.02572	0.01858	RASGRP1/DDX58/SYK/CD80/IL18/IL1B	6
BP	GO:0033008	positive regulation of mast cell activation involved in immune response	6/2112	15/18670	0.004209	0.02572	0.01858	IL4R/GATA2/FGR/SYK/STXBP1/GAB2	6
BP	GO:0043306	positive regulation of mast cell degranulation	6/2112	15/18670	0.004209	0.02572	0.01858	IL4R/GATA2/FGR/SYK/STXBP1/GAB2	6
BP	GO:0051299	centrosome separation	6/2112	15/18670	0.004209	0.02572	0.01858	KIF11/KIF3B/MAP9/NEK2/CEP85/AURKA	6
BP	GO:2001028	positive regulation of endothelial cell chemotaxis	6/2112	15/18670	0.004209	0.02572	0.01858	FGF18/PRKD2/FGF2/HSPB1/PRKD1/KDR	6
BP	GO:0016054	organic acid catabolic process	46/2112	275/18670	0.004282	0.02611	0.01886	FAH/CDO1/IDO1/ALDH7A1/PCYOX1/KYNU/ALDH3A2/ACADVL/ACOX2/HMMR/ALDH6A1/CBS/PCBD1/OAT/DDAH2/FGF2/LYVE1/MCCC1/ECHDC2/ASPA/ACAT1/PCK1/ETFB/ACACB/PGD/HYAL1/HPD/PCCA/MAT1A/IDUA/NAGK/LEP/BDH2/KMO/ECI2/ADIPOQ/ECI1/BCKDHB/ACADL/HADH/AASS/ECHS1/STAB2/ALDH5A1/HADHA/TXN2	46
BP	GO:0046395	carboxylic acid catabolic process	46/2112	275/18670	0.004282	0.02611	0.01886	FAH/CDO1/IDO1/ALDH7A1/PCYOX1/KYNU/ALDH3A2/ACADVL/ACOX2/HMMR/ALDH6A1/CBS/PCBD1/OAT/DDAH2/FGF2/LYVE1/MCCC1/ECHDC2/ASPA/ACAT1/PCK1/ETFB/ACACB/PGD/HYAL1/HPD/PCCA/MAT1A/IDUA/NAGK/LEP/BDH2/KMO/ECI2/ADIPOQ/ECI1/BCKDHB/ACADL/HADH/AASS/ECHS1/STAB2/ALDH5A1/HADHA/TXN2	46
BP	GO:0034142	toll-like receptor 4 signaling pathway	10/2112	35/18670	0.004299	0.02613	0.01888	TNFAIP3/ITGB2/RIPK2/NFKBIA/MFHAS1/TNIP3/PTPN22/NR1H3/LYN/RAB11FIP2	10
BP	GO:0045622	regulation of T-helper cell differentiation	10/2112	35/18670	0.004299	0.02613	0.01888	CCL19/IRF4/IL4R/MALT1/RIPK2/TBX21/CD86/CD80/IL18/NLRP3	10
BP	GO:0060251	regulation of glial cell proliferation	10/2112	35/18670	0.004299	0.02613	0.01888	PRKCH/SKI/ETV5/IDH2/PTN/NOTCH1/IL6/LYN/RNF10/IL1B	10
BP	GO:0031348	negative regulation of defense response	41/2112	239/18670	0.004306	0.02613	0.01888	SLAMF8/PTPRC/TNFAIP3/IGF1/NT5E/HLA-F/TNFRSF1B/CST7/CD200/PTPN2/HTRA1/HLA-G/LGALS9/NMI/CD96/MICB/TRAFD1/HLA-E/ADA/TSPAN6/CR1/HGF/SOD1/C5orf30/NFKB1/SMAD3/MFHAS1/ADAR/PTGER4/ADIPOQ/TRIM38/NR1H3/FPR2/RB1/SPINK5/PBK/IL2RA/MMP12/CDH5/LILRB1/NLRP3	41
BP	GO:0070302	regulation of stress-activated protein kinase signaling cascade	41/2112	239/18670	0.004306	0.02613	0.01888	SFRP1/SLAMF1/RASGRP1/CCL19/TPD52L1/SEMA3A/CCR7/MAP3K11/NOD2/RIPK2/EGFR/SPHK1/MAP4K1/CCL21/HGF/CD27/EPHB1/CD40LG/ARL6IP5/FZD4/FOXO1/FZD7/MFHAS1/ZMYND11/MAP3K2/LEP/PAK1/DACT1/SYK/PHLPP1/PINK1/PTPN22/IL1RN/LYN/NOD1/HIPK2/NCF1/PRMT1/PBK/TLR6/IL1B	41
BP	GO:0060421	positive regulation of heart growth	13/2112	52/18670	0.004373	0.02651	0.01915	IGF1/PIM1/ZFPM2/BMPR1A/YAP1/FGF2/TGFBR3/CDK1/ACACB/NOTCH1/CCNB1/HEY2/FGF9	13
BP	GO:1901861	regulation of muscle tissue development	29/2112	155/18670	0.004382	0.02653	0.01917	BMP4/IGFBP5/IGF1/PIM1/CDON/MEIS1/ZFPM2/SIX1/BMPR1A/HDAC4/SHOX2/YAP1/FGF2/TGFBR3/CDK1/KCNK2/EPHB1/LEF1/SMAD3/FZD7/RBP4/NOTCH1/ARNTL/CCNB1/HEY2/PAK1/FGF9/CENPF/JARID2	29
BP	GO:0034121	regulation of toll-like receptor signaling pathway	16/2112	70/18670	0.004387	0.02654	0.01918	TNFAIP3/IRF1/BIRC3/TLR2/IRF4/IRF7/CD36/TLR5/PTPRS/MFHAS1/GFI1/PTPN22/NR1H3/CYBA/LYN/TLR6	16
BP	GO:0046834	lipid phosphorylation	15/2112	64/18670	0.00445	0.02683	0.01938	PIK3R1/PIP4K2B/SOCS1/CISH/SPHK1/SOCS2/PIK3CD/INPP1/SOCS6/DGKA/PIK3CA/PIK3R3/PIP4K2A/CERK/BPNT1	15
BP	GO:0050922	negative regulation of chemotaxis	15/2112	64/18670	0.00445	0.02683	0.01938	CXCL13/SLAMF8/SEMA4A/SEMA4D/SEMA3A/PTPN2/GPR18/RYK/SEMA3F/NOTCH1/NBL1/SEMA4F/SEMA3E/SEMA6B/CCL2	15
BP	GO:0035306	positive regulation of dephosphorylation	14/2112	58/18670	0.004452	0.02683	0.01938	PTPRC/LILRB2/JAK2/DLC1/PLEK/MAGI2/PPP1R16B/SMAD3/IFNG/RGN/HSP90AB1/PINK1/CAMTA1/CDH5	14
BP	GO:1904589	regulation of protein import	14/2112	58/18670	0.004452	0.02683	0.01938	PIK3R1/BMP4/ZIC1/GLI3/ANGPT1/HCLS1/CD36/TPR/ZPR1/SMAD3/ECT2/LEP/IFNG/FERMT1	14
BP	GO:0030323	respiratory tube development	32/2112	176/18670	0.004509	0.02715	0.01962	BMP4/IGFBP5/DLG5/FGF18/SOX9/GLI3/LTBP3/FGF7/ZFPM2/BMPR1A/ADAMTSL2/YAP1/EGFR/PDPN/ADA/DAG1/NFIB/PTN/RBP4/NOTCH1/TIMELESS/PPP1CA/TNS3/FGF9/TGFB3/TULP3/RCN3/CEBPA/FSTL3/HOXA5/THRA/CTSH	32
BP	GO:0032607	interferon-alpha production	9/2112	30/18670	0.004657	0.02799	0.02022	TLR8/STAT1/IRF7/NMI/IFIH1/RIPK2/DDX58/PTPRS/MMP12	9
BP	GO:0032728	positive regulation of interferon-beta production	9/2112	30/18670	0.004657	0.02799	0.02022	IRF1/TLR8/ZBTB20/TLR2/IRF7/IFIH1/RIPK2/DDX58/PTPN11	9
BP	GO:0000727	double-strand break repair via break-induced replication	5/2112	11/18670	0.004733	0.0281	0.02031	CDC45/MCM5/CDC7/MCM2/MCM4	5
BP	GO:0001767	establishment of lymphocyte polarity	5/2112	11/18670	0.004733	0.0281	0.02031	CCL19/CCR7/CCL21/DOCK2/GSN	5
BP	GO:0019852	L-ascorbic acid metabolic process	5/2112	11/18670	0.004733	0.0281	0.02031	CYB5R3/SLC2A3/RGN/SLC23A2/GSTO1	5
BP	GO:0033632	regulation of cell-cell adhesion mediated by integrin	5/2112	11/18670	0.004733	0.0281	0.02031	CCL5/CXCL13/CD3E/ADA/SKAP1	5
BP	GO:0035404	histone-serine phosphorylation	5/2112	11/18670	0.004733	0.0281	0.02031	VRK1/RPS6KA4/CCNB1/AURKB/AURKA	5
BP	GO:0035747	natural killer cell chemotaxis	5/2112	11/18670	0.004733	0.0281	0.02031	CCL5/XCL1/PIK3CD/CCL7/CCL2	5
BP	GO:0051024	positive regulation of immunoglobulin secretion	5/2112	11/18670	0.004733	0.0281	0.02031	HLA-E/RBP4/STX4/TNFRSF4/IL6	5
BP	GO:0055015	ventricular cardiac muscle cell development	5/2112	11/18670	0.004733	0.0281	0.02031	MYH10/CDK1/CCNB1/HEY2/LMNA	5
BP	GO:0060433	bronchus development	5/2112	11/18670	0.004733	0.0281	0.02031	BMP4/SOX9/ADAMTSL2/TULP3/HOXA5	5
BP	GO:0070757	interleukin-35-mediated signaling pathway	5/2112	11/18670	0.004733	0.0281	0.02031	IL27RA/STAT1/JAK2/STAT4/IL6ST	5
BP	GO:2000551	regulation of T-helper 2 cell cytokine production	5/2112	11/18670	0.004733	0.0281	0.02031	XCL1/TBX21/IL6/CD81/NLRP3	5
BP	GO:0006970	response to osmotic stress	18/2112	83/18670	0.004736	0.0281	0.02031	RELB/AQP9/DYSF/AKR1B1/EGFR/MICU1/MAPK13/ZFP36L1/KMO/SLC12A2/HSP90AB1/MBIP/SLC25A23/ICOSLG/LRRC8D/PKD2/MYLK/TP53	18
BP	GO:0043500	muscle adaptation	24/2112	122/18670	0.004736	0.0281	0.02031	IGFBP5/IGF1/TNFRSF1B/IL15/PPP3CA/HDAC4/GTF2IRD2B/EZH2/FOXO1/SMAD3/NOTCH1/MYOC/IL6ST/GTF2IRD1/HEY2/PAK1/PARP1/JARID2/FOXO3/LMNA/CYBA/CFLAR/GSN/IL1B	24
BP	GO:0035136	forelimb morphogenesis	11/2112	41/18670	0.004769	0.02819	0.02037	GDF5/ZBTB16/SHOX2/ZNF358/RECK/TP63/ATRX/TFAP2A/HOXD10/NIPBL/HOXA11	11
BP	GO:1902893	regulation of pri-miRNA transcription by RNA polymerase II	11/2112	41/18670	0.004769	0.02819	0.02037	BMP4/SOX9/BMPR1A/HDAC4/GATA2/NFIB/LILRB4/SMAD3/PRL/SPI1/TP53	11
BP	GO:1903053	regulation of extracellular matrix organization	11/2112	41/18670	0.004769	0.02819	0.02037	DDR2/TNFRSF1B/SOX9/ANTXR1/PDPN/DAG1/SMAD3/NOTCH1/IL6/RB1/CFLAR	11
BP	GO:0002374	cytokine secretion involved in immune response	7/2112	20/18670	0.004792	0.02819	0.02037	TNFRSF1B/TLR2/ANGPT1/NOD2/TNFRSF14/LILRB1/NLRP3	7
BP	GO:0006271	DNA strand elongation involved in DNA replication	7/2112	20/18670	0.004792	0.02819	0.02037	LIG1/RFC3/GINS1/FEN1/RNASEH2A/MCM4/GINS3	7
BP	GO:0010560	positive regulation of glycoprotein biosynthetic process	7/2112	20/18670	0.004792	0.02819	0.02037	IGF1/CCL19/IL15/CCR7/GOLGA2/CCL21/TCF7L2	7
BP	GO:0032816	positive regulation of natural killer cell activation	7/2112	20/18670	0.004792	0.02819	0.02037	RASGRP1/HLA-F/IL15/AXL/HLA-E/TOX/IL18	7
BP	GO:0033005	positive regulation of mast cell activation	7/2112	20/18670	0.004792	0.02819	0.02037	IL4R/GATA2/FGR/CD226/SYK/STXBP1/GAB2	7
BP	GO:0034104	negative regulation of tissue remodeling	7/2112	20/18670	0.004792	0.02819	0.02037	SFRP1/TNFAIP3/TNFRSF11B/CSK/IL6/CD38/INPP5D	7
BP	GO:0072009	nephron epithelium development	22/2112	109/18670	0.004858	0.02842	0.02054	BMP4/STAT1/SOX9/GLI3/FOXC1/SIX1/SIX2/YAP1/FGF2/MAGI2/ACAT1/PBX1/DCHS1/NOTCH1/PECAM1/ADIPOQ/WWTR1/FAT4/PKD2/POU3F3/HOXA11/AHI1	22
BP	GO:0002719	negative regulation of cytokine production involved in immune response	8/2112	25/18670	0.004869	0.02842	0.02054	XCL1/HLA-F/ANGPT1/CD96/TBX21/HFE/TGFB3/LILRB1	8
BP	GO:0034110	regulation of homotypic cell-cell adhesion	8/2112	25/18670	0.004869	0.02842	0.02054	CCL5/PRKCQ/PDPN/CD9/SYK/PRKG1/LYN/SH2B3	8
BP	GO:0045662	negative regulation of myoblast differentiation	8/2112	25/18670	0.004869	0.02842	0.02054	BMP4/SOX9/CXCL10/ID3/NOTCH1/DDIT3/IL18/CCL17	8
BP	GO:0060330	regulation of response to interferon-gamma	8/2112	25/18670	0.004869	0.02842	0.02054	STAT1/PTPN2/JAK2/SOCS1/TXK/IFNG/HSP90AB1/NR1H3	8
BP	GO:0060334	regulation of interferon-gamma-mediated signaling pathway	8/2112	25/18670	0.004869	0.02842	0.02054	STAT1/PTPN2/JAK2/SOCS1/TXK/IFNG/HSP90AB1/NR1H3	8
BP	GO:0072202	cell differentiation involved in metanephros development	8/2112	25/18670	0.004869	0.02842	0.02054	BMP4/STAT1/SIX2/YAP1/ADIPOQ/WWTR1/FAT4/POU3F3	8
BP	GO:2000353	positive regulation of endothelial cell apoptotic process	8/2112	25/18670	0.004869	0.02842	0.02054	ITGA4/AKR1C3/HLA-G/CD40/CD160/CD40LG/FOXO3/CCL2	8
BP	GO:0048469	cell maturation	32/2112	177/18670	0.004922	0.02871	0.02074	CDKN1C/CCL19/IL15/AXL/NPR2/GATA2/CDC25B/CLEC7A/CCL21/SCARF1/DAZL/IRX5/MYOC/CCNB1/MECP2/EDNRB/FBXO5/TRIM58/BTK/REC8/TYMS/BCL11A/FOXO3/RB1/ANG/CEBPA/REN/PTH1R/TRIP13/AURKA/PTBP3/HOXA5	32
BP	GO:0042176	regulation of protein catabolic process	60/2112	381/18670	0.005029	0.02931	0.02118	LAMP3/NELL1/TNFAIP3/TIMP3/CLU/TNFRSF1B/SOX9/DTL/NFE2L1/AREL1/TIMP4/CBFA2T3/ADAM8/DYSF/MAD2L1/CTSC/PLK1/TIMP2/PSME1/EGFR/GABARAPL2/CHFR/BARD1/BAG2/NDUFA13/RHBDF1/FOXO1/SMAD3/EDEM1/PLK2/ARNTL/VCP/MYLIP/IFNG/RGN/HSP90AB1/DACT1/HFE/PINK1/RNF19B/UBE2J1/GFAP/CUL4B/CEBPA/HIPK2/DVL1/CD81/BAG5/EDEM2/ALAD/WAC/PBK/ATRAID/USP7/CAMLG/AURKA/RNF14/IL1B/UBE2G2/PML	60
BP	GO:0035722	interleukin-12-mediated signaling pathway	12/2112	47/18670	0.00506	0.02943	0.02126	LCP1/LMNB1/JAK2/STAT4/HNRNPDL/SOD1/IFNG/CFL1/CAPZA1/GSTO1/TALDO1/TYK2	12
BP	GO:0061614	pri-miRNA transcription by RNA polymerase II	12/2112	47/18670	0.00506	0.02943	0.02126	BMP4/SOX9/BMPR1A/HDAC4/GATA2/NFIB/LILRB4/SMAD3/PRL/FOSL1/SPI1/TP53	12
BP	GO:0031056	regulation of histone modification	27/2112	143/18670	0.005135	0.02984	0.02156	NAP1L2/SKI/AUTS2/PRKD2/GATA2/UBE2B/KMT2A/TAF7/RPS6KA4/DNMT1/ATRX/BRD4/PAX5/CCNB1/EID1/MECP2/MTF2/GFI1/SPI1/NIPBL/PAF1/PINK1/JARID2/LMNA/PRKD1/TP53/IL1B	27
BP	GO:0001656	metanephros development	19/2112	90/18670	0.005144	0.02984	0.02156	BMP4/DLG5/STAT1/SOX9/GLI3/SIX1/SIX2/YAP1/AKR1B1/ACAT1/ID3/ADIPOQ/NIPBL/WWTR1/FAT4/PKD2/POU3F3/HOXA11/CTSH	19
BP	GO:0014033	neural crest cell differentiation	19/2112	90/18670	0.005144	0.02984	0.02156	KITLG/SFRP1/BMP4/LRP6/SEMA4A/SOX9/SEMA4D/FOXC1/SEMA3A/BMPR1A/HTR2B/FAM172A/SEMA3F/ACVR1/EDNRB/CFL1/SEMA4F/SEMA3E/SEMA6B	19
BP	GO:0050704	regulation of interleukin-1 secretion	13/2112	53/18670	0.005207	0.03014	0.02178	AIM2/TNFAIP3/TLR8/CCL19/CCR7/LGALS9/NOD2/RIPK2/CASP1/SERPINB1/PANX1/PML/NLRP3	13
BP	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	13/2112	53/18670	0.005207	0.03014	0.02178	SFRP1/PTPRC/SEMA4D/SH3BP5/PPP2CA/PTPN2/SAMSN1/SOCS1/GPRC5A/PTPN6/ZGPAT/SH2B3/MVP	13
BP	GO:0060562	epithelial tube morphogenesis	52/2112	322/18670	0.005218	0.03016	0.02179	SFRP1/BMP4/LRP6/DLG5/CXCR4/SOX9/GLI3/SKI/RASIP1/AR/SIX1/SIX2/COBL/PRKD2/YAP1/CXCL10/DAG1/DLC1/FGF2/ETV5/SPINT2/LRP5/PBX1/DCHS1/TCTN1/LEF1/SMAD3/VASP/NOTCH1/TIMELESS/PPP1CA/PAK1/ACVR1/ITGAX/TULP3/APAF1/FZD6/MEGF8/FAT4/CFL1/SEMA3E/PKD2/DVL1/KIF20B/HOXA11/FZD2/PFN1/HOXA5/PML/CTSH/STIL/AHI1	52
BP	GO:0008203	cholesterol metabolic process	28/2112	150/18670	0.00522	0.03016	0.02179	LBR/APOL1/ACADVL/ABCG1/NFE2L1/PMVK/CYB5R3/NPC1/ERLIN1/SP1/SCARF1/SOD1/ACACB/SC5D/LEP/NFYA/ERLIN2/CETP/HDLBP/OSBPL1A/MBTPS2/CYP46A1/CEBPA/ACADL/CAT/LIPC/EPHX2/SOAT2	28
BP	GO:0006109	regulation of carbohydrate metabolic process	36/2112	206/18670	0.005288	0.0305	0.02204	ENPP1/IGF1/ZBTB20/NFE2L1/PTPN2/SLC2A6/CBFA2T3/NUP93/HDAC4/PASK/TPR/PLEK/SIK1/COX11/NUP160/ACACB/FAM3C/NFKB1/PMAIP1/HTR2A/FOXO1/HRH1/LEP/IFNG/ARNT/PPP1CA/RGN/ADIPOQ/P2RY6/PDK4/SORBS1/SCARB2/NUP88/PTH1R/NUP50/TP53	36
BP	GO:0045926	negative regulation of growth	42/2112	249/18670	0.005288	0.0305	0.02204	ENPP1/CDKN2C/SFRP1/BMP4/IGFBP5/SEMA4A/SIPA1/SEMA4D/SEMA3A/INHBA/PPP2CA/MEIS1/CRLF3/CRYAB/NDRG3/PLAC8/FHL1/FGF13/KCNK2/SOCS2/TSPYL2/NDUFA13/RYK/PTPRS/SEMA3F/HYAL1/SMAD3/SMARCA2/RBP4/NOTCH1/PAK1/ARHGAP4/BCL11A/SEMA4F/JARID2/SEMA3E/SEMA6B/TP53/DCBLD2/EAF2/MT1X/PML	42
BP	GO:0006633	fatty acid biosynthetic process	30/2112	164/18670	0.005328	0.0307	0.02218	LTC4S/PLP1/AKR1C3/ACADVL/CD74/ERLIN1/FA2H/HPGDS/ACACB/GPX4/HSD17B12/LIPG/RGN/ADIPOQ/ERLIN2/FABP5/PDK4/PTGS1/ELOVL4/NR1H3/ACADL/ELOVL2/ACSM5/ACSM3/LIPC/PRKAB1/IL1B/EPHX2/ALOX5/ELOVL5	30
BP	GO:0034314	Arp2/3 complex-mediated actin nucleation	10/2112	36/18670	0.00536	0.03084	0.02228	WASL/WAS/GMFG/ARPC5L/AP1AR/ARPC1A/ABI2/ACTR3/IQGAP2/ACTR2	10
BP	GO:0046328	regulation of JNK cascade	33/2112	185/18670	0.005364	0.03084	0.02228	SFRP1/SLAMF1/RASGRP1/CCL19/TPD52L1/SEMA3A/CCR7/MAP3K11/NOD2/RIPK2/EGFR/MAP4K1/CCL21/CD27/EPHB1/CD40LG/FZD4/FZD7/MFHAS1/ZMYND11/MAP3K2/PAK1/DACT1/SYK/PHLPP1/PINK1/PTPN22/IL1RN/NOD1/HIPK2/NCF1/TLR6/IL1B	33
BP	GO:0050821	protein stabilization	32/2112	178/18670	0.005367	0.03084	0.02228	PIK3R1/IGF1/CLU/PIM1/ANK2/PFN2/CRYAB/TNIP2/UBE2B/CRTAP/BAG2/ZNF207/ATP1B1/SMAD3/HSP90AB1/PEX19/STXBP1/PINK1/PER3/TESC/NLK/CDC37L1/DVL1/BAG5/GOLGA7/AFM/PFN1/TP53/USP7/PIM2/CAMLG/TBL1X	32
BP	GO:0006024	glycosaminoglycan biosynthetic process	22/2112	110/18670	0.00544	0.0312	0.02254	PRELP/FMOD/GPC5/OGN/CHST15/ANGPT1/EXTL2/CHST3/DCN/BGN/CSPG4/CHST11/LUM/NFKB1/VCAN/HYAL1/UGDH/GPC4/EXT2/B3GNT2/IL1B/B4GALT2	22
BP	GO:0032508	DNA duplex unwinding	22/2112	110/18670	0.00544	0.0312	0.02254	PURA/CETN2/CHD1/CDC45/BLM/MCM5/RFC3/TOP2A/GINS1/ATRX/NAV2/MCM2/DDX1/CHD4/PARP1/ACTR8/MCM4/CUL4B/ERCC6L/HMGA1/CHD9/GTF2H5	22
BP	GO:0060560	developmental growth involved in morphogenesis	40/2112	235/18670	0.005456	0.03126	0.02259	SFRP1/BMP4/LRP6/SEMA4A/CXCR4/NDN/SOX9/ITGA4/SEMA4D/SEMA3A/AUTS2/SIX1/COBL/YAP1/FGF13/TRPV2/MAGI2/RYK/PTPRS/SEMA3F/CYFIP2/EFNA5/NOTCH1/GDI1/SYT17/HSP90AB1/PAK1/CTTN/MAP1B/ARHGAP4/MEGF8/BCL11A/DPYSL2/SEMA4F/SEMA3E/DVL1/SEMA6B/S1PR1/AURKA/DCLK1	40
BP	GO:0014706	striated muscle tissue development	61/2112	390/18670	0.005473	0.03133	0.02264	SGCB/BMP4/IGF1/MYH10/HLF/PIM1/FOXC1/SKI/PPP3CA/CDON/MEIS1/HIVEP3/CBY1/ZFPM2/EYA2/SIX1/BMPR1A/HDAC4/SHOX2/YAP1/FGF2/TGFBR3/DCN/CDK1/SIK1/KCNK2/SORBS2/PLN/EPHB1/PDLIM5/NOX4/SGCD/PITX1/LEF1/SMAD3/FZD7/RBP4/NOTCH1/ARNTL/PAX5/CCNB1/HEY2/SLC8A1/PAK1/POPDC2/ACVR1/FGF9/HOXD10/CENPF/AKAP13/JARID2/MYH11/LMNA/RB1/KCNAB1/GJC1/TENM4/CFLAR/MYL6B/S1PR1/ALPK3	61
BP	GO:0030316	osteoclast differentiation	20/2112	97/18670	0.005502	0.03147	0.02274	PIK3R1/SFRP1/GPR183/TCIRG1/LILRB3/TFRC/SH3PXD2A/CCR1/LILRB4/CA2/GLO1/IFNG/INPP5D/GAB2/FSTL3/SNX10/CD81/TOB2/SBNO2/LILRB1	20
BP	GO:0048193	Golgi vesicle transport	58/2112	368/18670	0.005642	0.03224	0.0233	COPZ2/SERPINA1/GAS1/TAPBP/ARL1/CSK/PREPL/RAB8A/ANK2/GAK/COG5/CTSC/GOLGA2/DYNC1LI2/GABARAPL2/ATP9A/KIF11/KIF15/PROS1/F5/KIF3B/SEC31A/GOLGA3/CREB3L2/RAB33B/KIF2C/KIF4A/DYNC1I1/YIPF5/KDELR3/TRIM23/RACGAP1/VCP/KIF16B/STX18/STX4/BBS1/ANKRD28/DCTN6/VAMP2/KDELR2/BCAP29/CAPZA1/AP1AR/PRKD1/NBAS/GOLGB1/ERGIC2/ARL3/GOLGA7/STX6/VTI1B/CNIH1/SEC23B/RAB14/SPTBN1/USE1/KIF23	58
BP	GO:0055021	regulation of cardiac muscle tissue growth	17/2112	78/18670	0.005648	0.03225	0.0233	IGF1/PIM1/MEIS1/ZFPM2/BMPR1A/YAP1/FGF2/TGFBR3/CDK1/KCNK2/RBP4/NOTCH1/CCNB1/HEY2/PAK1/FGF9/JARID2	17
BP	GO:0016999	antibiotic metabolic process	28/2112	151/18670	0.005733	0.0327	0.02363	RAC2/AKR1C3/ADH1C/HBB/AKR1B1/EGFR/ESD/AKR1C1/IDH2/PCK1/SOD1/GPX3/SUCLA2/NAGK/HBD/CYP4B1/ADH1B/PRDX6/PINK1/MDH1/MAOB/ADH5/HP/CYBA/SDHA/CAT/AKR7A2/ALDH5A1	28
BP	GO:1901992	positive regulation of mitotic cell cycle phase transition	19/2112	91/18670	0.005828	0.03321	0.024	DTL/CCND2/UBE2C/EGFR/CDC45/CDC25B/SMARCD3/CDK1/DLGAP5/PBX1/HYAL1/BRD4/CDC7/CCNB1/MECP2/CCND1/FBXO5/RB1/CUL4B	19
BP	GO:0030324	lung development	31/2112	172/18670	0.005842	0.03324	0.02402	BMP4/IGFBP5/DLG5/FGF18/SOX9/GLI3/LTBP3/FGF7/ZFPM2/BMPR1A/ADAMTSL2/YAP1/EGFR/PDPN/ADA/DAG1/NFIB/PTN/RBP4/NOTCH1/TIMELESS/PPP1CA/TNS3/FGF9/TGFB3/RCN3/CEBPA/FSTL3/HOXA5/THRA/CTSH	31
BP	GO:0030177	positive regulation of Wnt signaling pathway	32/2112	179/18670	0.005844	0.03324	0.02402	PSMB9/SFRP1/TNFAIP3/PSMB8/GPC5/ASPM/PSMB10/SKI/TLR2/SULF1/WLS/ZBED2/YAP1/PSME1/EGFR/UBE2B/RECK/PLEKHA4/NFKB1/SMAD3/DIXDC1/DAAM2/ARNTL/VCP/KANK1/DACT1/FGF9/RNF146/NLE1/FRAT1/TBL1X/SPIN1	32
BP	GO:0048284	organelle fusion	24/2112	124/18670	0.00585	0.03324	0.02402	PID1/TAP1/TAPBP/CORO1A/TAP2/RAB8A/LRMP/DYSF/SPHK1/SAMD9/CDK1/VCPIP1/BAK1/PCDHGA3/STX16/AFG3L2/VPS16/RAB20/STX4/STXBP1/CHMP2B/STX6/VTI1B/VAV3	24
BP	GO:0060193	positive regulation of lipase activity	16/2112	72/18670	0.005862	0.03329	0.02405	CCL5/ITK/ARL1/NTRK2/LPAR1/HTR2B/EGFR/FGF2/SELE/TXK/HTR2A/AGTR1/P2RY6/NR1H3/ANG/S1PR4	16
BP	GO:0007143	female meiotic nuclear division	9/2112	31/18670	0.005915	0.03349	0.0242	PLK1/NCAPH/CDC25B/DAZL/TOP2A/FBXO5/TTK/TRIP13/AURKA	9
BP	GO:0010543	regulation of platelet activation	9/2112	31/18670	0.005915	0.03349	0.0242	PRKCQ/PDPN/PLEK/CD9/SYK/TEC/PRKG1/LYN/SH2B3	9
BP	GO:0090075	relaxation of muscle	9/2112	31/18670	0.005915	0.03349	0.0242	SRI/PLN/SOD1/KCNJ2/ATP1B1/ATP1A2/SLC8A1/PRKG1/GSTM2	9
BP	GO:1904888	cranial skeletal system development	15/2112	66/18670	0.006033	0.03413	0.02466	BMP4/GLI3/SIX1/SIX2/CEP55/CHST11/TP63/SMAD3/IRX5/PAX5/TFAP2A/TGFB3/NIPBL/TULP3/MEGF8	15
BP	GO:0055023	positive regulation of cardiac muscle tissue growth	12/2112	48/18670	0.006066	0.03415	0.02467	IGF1/PIM1/ZFPM2/BMPR1A/YAP1/FGF2/TGFBR3/CDK1/NOTCH1/CCNB1/HEY2/FGF9	12
BP	GO:0014896	muscle hypertrophy	22/2112	111/18670	0.006077	0.03415	0.02467	IGFBP5/IGF1/TNFRSF1B/PPP3CA/HDAC4/HTR2B/EZH2/SORBS2/PDLIM5/FOXO1/SMAD3/NOTCH1/MYOC/LEP/IL6ST/HEY2/PAK1/PARP1/AKAP13/JARID2/LMNA/CYBA	22
BP	GO:0021537	telencephalon development	42/2112	251/18670	0.006094	0.03415	0.02467	BMP4/BCL11B/LRP6/TACC3/GNG12/ASPM/BCL2A1/MYH10/CXCR4/GLI3/NTRK2/TSKU/SEMA3A/SKI/INHBA/CDON/LPAR1/ANXA3/EGFR/NFIB/FGF13/TACC1/EZH2/CDH2/MCPH1/RYK/PTPRS/TCTN1/LEF1/DIXDC1/FEZ1/TACC2/PAX5/SLC8A1/FAT4/EMX2/CRTAC1/POU3F3/EZH1/RFX4/FEZF2/MBOAT7	42
BP	GO:0002643	regulation of tolerance induction	6/2112	16/18670	0.006097	0.03415	0.02467	CD3E/IDO1/LILRB2/HLA-G/PHLPP1/IL2RA	6
BP	GO:0010820	positive regulation of T cell chemotaxis	6/2112	16/18670	0.006097	0.03415	0.02467	CCL5/CXCL13/XCL1/CCR2/CCL21/ADAM10	6
BP	GO:0030397	membrane disassembly	6/2112	16/18670	0.006097	0.03415	0.02467	PRKCB/CCNB2/VRK1/PLK1/CDK1/CCNB1	6
BP	GO:0032604	granulocyte macrophage colony-stimulating factor production	6/2112	16/18670	0.006097	0.03415	0.02467	RASGRP1/DDX58/SYK/CD80/IL18/IL1B	6
BP	GO:0033631	cell-cell adhesion mediated by integrin	6/2112	16/18670	0.006097	0.03415	0.02467	CCL5/CXCL13/CD3E/ITGA4/ADA/SKAP1	6
BP	GO:0043217	myelin maintenance	6/2112	16/18670	0.006097	0.03415	0.02467	CLU/CXCR4/FA2H/SOD1/MPP5/SH3TC2	6
BP	GO:0051081	nuclear envelope disassembly	6/2112	16/18670	0.006097	0.03415	0.02467	PRKCB/CCNB2/VRK1/PLK1/CDK1/CCNB1	6
BP	GO:0055119	relaxation of cardiac muscle	6/2112	16/18670	0.006097	0.03415	0.02467	PLN/KCNJ2/ATP1B1/ATP1A2/SLC8A1/GSTM2	6
BP	GO:0033260	nuclear DNA replication	14/2112	60/18670	0.006141	0.03436	0.02483	LIG1/CDC45/MCM5/RFC3/GINS1/FEN1/ATRX/DONSON/CDC7/MCM2/TERF1/DBF4/POLE2/MCM4	14
BP	GO:0048864	stem cell development	18/2112	85/18670	0.006149	0.03438	0.02484	KITLG/PTPRC/BMP4/SEMA4A/SOX9/SEMA4D/FOXC1/SEMA3A/BMPR1A/HTR2B/FAM172A/SEMA3F/ACVR1/EDNRB/CFL1/SEMA4F/SEMA3E/SEMA6B	18
BP	GO:0010524	positive regulation of calcium ion transport into cytosol	13/2112	54/18670	0.006163	0.03439	0.02485	CXCL9/XCL1/SRI/CXCL10/BAK1/TRPC1/CD19/CXCL11/P2RY6/APLNR/PKD2/GSTO1/GSTM2	13
BP	GO:0097345	mitochondrial outer membrane permeabilization	13/2112	54/18670	0.006163	0.03439	0.02485	TFDP2/GZMB/BID/EYA2/TMEM14A/BAK1/TP63/PMAIP1/SLC25A5/TP53BP2/TP53/BNIP3L/MOAP1	13
BP	GO:0016202	regulation of striated muscle tissue development	28/2112	152/18670	0.006289	0.03506	0.02533	BMP4/IGF1/PIM1/CDON/MEIS1/ZFPM2/SIX1/BMPR1A/HDAC4/SHOX2/YAP1/FGF2/TGFBR3/CDK1/KCNK2/EPHB1/LEF1/SMAD3/FZD7/RBP4/NOTCH1/ARNTL/CCNB1/HEY2/PAK1/FGF9/CENPF/JARID2	28
BP	GO:0032872	regulation of stress-activated MAPK cascade	40/2112	237/18670	0.006311	0.03515	0.0254	SFRP1/SLAMF1/RASGRP1/CCL19/TPD52L1/SEMA3A/CCR7/MAP3K11/NOD2/RIPK2/EGFR/SPHK1/MAP4K1/CCL21/HGF/CD27/EPHB1/CD40LG/ARL6IP5/FZD4/FOXO1/FZD7/MFHAS1/ZMYND11/MAP3K2/LEP/PAK1/DACT1/SYK/PHLPP1/PINK1/PTPN22/IL1RN/NOD1/HIPK2/NCF1/PRMT1/PBK/TLR6/IL1B	40
BP	GO:0030206	chondroitin sulfate biosynthetic process	8/2112	26/18670	0.006346	0.03526	0.02547	CHST15/CHST3/DCN/BGN/CSPG4/CHST11/VCAN/UGDH	8
BP	GO:0048843	negative regulation of axon extension involved in axon guidance	8/2112	26/18670	0.006346	0.03526	0.02547	SEMA4A/SEMA4D/SEMA3A/RYK/SEMA3F/SEMA4F/SEMA3E/SEMA6B	8
BP	GO:0051125	regulation of actin nucleation	8/2112	26/18670	0.006346	0.03526	0.02547	CORO1A/ARPIN/WASL/WAS/GMFG/AP1AR/ABI2/GSN	8
BP	GO:0016125	sterol metabolic process	30/2112	166/18670	0.00636	0.0353	0.0255	LBR/APOL1/ACADVL/ABCG1/NFE2L1/PMVK/CYB5R3/NPC1/FAXDC2/ERLIN1/SP1/SCARF1/SOD1/ACACB/CYB5R1/SC5D/LEP/NFYA/ERLIN2/CETP/HDLBP/OSBPL1A/MBTPS2/CYP46A1/CEBPA/ACADL/CAT/LIPC/EPHX2/SOAT2	30
BP	GO:0009743	response to carbohydrate	39/2112	230/18670	0.006412	0.03556	0.02569	ZBTB20/SRI/OXCT1/PPP3CA/PRKCB/ICAM1/KLF7/CLEC7A/MPC2/TCF7L2/PCK1/LRP5/NOX4/MAPK13/RMI1/EFNA5/COLEC12/LEP/ZFP36L1/PIK3CA/SLC8A1/ADIPOQ/STX4/VAMP2/NDUFA9/MAP1B/SYBU/FOXO3/ENSA/CYBA/LYN/CAT/ERCC1/RAB11FIP2/SLC2A5/IL1B/ZNF236/GPR27/TXN2	39
BP	GO:0001779	natural killer cell differentiation	7/2112	21/18670	0.006496	0.03589	0.02593	PTPRC/RASGRP1/IL15/AXL/PIK3CD/TOX/MERTK	7
BP	GO:0035455	response to interferon-alpha	7/2112	21/18670	0.006496	0.03589	0.02593	LAMP3/AXL/MX2/TPR/IFIT3/ADAR/IFIT2	7
BP	GO:0048245	eosinophil chemotaxis	7/2112	21/18670	0.006496	0.03589	0.02593	CCL5/CCL13/SCG2/HRH1/CCL7/CCL2/CCL23	7
BP	GO:0140131	positive regulation of lymphocyte chemotaxis	7/2112	21/18670	0.006496	0.03589	0.02593	CCL5/CXCL13/XCL1/CCR2/CCL21/CCL7/ADAM10	7
BP	GO:0042307	positive regulation of protein import into nucleus	10/2112	37/18670	0.006615	0.03642	0.02632	PIK3R1/ZIC1/GLI3/HCLS1/TPR/ZPR1/SMAD3/ECT2/LEP/IFNG	10
BP	GO:0045730	respiratory burst	10/2112	37/18670	0.006615	0.03642	0.02632	SLAMF8/RAC2/CD52/CLEC7A/NCF4/CAMK1D/PIK3CD/CYBA/HCK/NCF1	10
BP	GO:0050691	regulation of defense response to virus by host	10/2112	37/18670	0.006615	0.03642	0.02632	AIM2/TNFAIP3/STAT1/IL15/APOBEC3G/MICB/DDX58/IL1B/MMP12/LILRB1	10
BP	GO:0060323	head morphogenesis	10/2112	37/18670	0.006615	0.03642	0.02632	PLEKHA1/LRP6/SKI/SGPL1/ASPH/RRAS/LEF1/PTPN11/TGFB3/NIPBL	10
BP	GO:0045598	regulation of fat cell differentiation	25/2112	132/18670	0.00663	0.03647	0.02635	ENPP1/FTO/SFRP1/WNT5B/LMO3/ZBTB16/RUNX1T1/ZFPM2/GATA2/AAMDC/ADIRF/LRP5/HTR2A/FOXO1/SMAD3/ARNTL/LEP/ZFP36L1/ADIPOQ/WWTR1/IL6/DDIT3/CEBPA/ZFP36L2/WIF1	25
BP	GO:0030258	lipid modification	40/2112	238/18670	0.006779	0.03726	0.02692	PIK3R1/ALDH3A2/ACADVL/ABCG1/ACOX2/PIP4K2B/SOCS1/CISH/SPHK1/ECHDC2/FA2H/ACAT1/SOCS2/PIK3CD/ETFB/ACACB/INPP1/LEP/AGTR1/BDH2/SOCS6/DGKA/PIK3CA/ECI2/ADIPOQ/PDK4/PIK3R3/ECI1/INPP5D/PIP4K2A/ACADL/HADH/ECHS1/MTMR2/PLA2G7/CERK/EPHX2/BPNT1/SOAT2/HADHA	40
BP	GO:0035264	multicellular organism growth	27/2112	146/18670	0.00683	0.03747	0.02707	PLEKHA1/FTO/GDF5/CDKN1C/IGF1/NPY1R/AR/SGPL1/PLAC8/COMP/GHR/SOCS2/AFG3L2/SOD1/RMI1/PTPN11/ATRX/ZFP36L1/PIK3CA/PRL/NIPBL/WWTR1/DIO3/ERCC1/TP53/HOXA5/STIL	27
BP	GO:0045834	positive regulation of lipid metabolic process	27/2112	146/18670	0.00683	0.03747	0.02707	ZBTB20/CCL19/CCR7/ABCG1/CD74/NOD2/HTR2B/FGR/FGF2/CCL21/HTR2A/CD19/AGTR1/IFNG/RGN/FLT3/ADIPOQ/SORBS1/NR1H3/FPR2/PRKD1/ABHD6/LYN/CD81/VAV3/IL1B/ELOVL5	27
BP	GO:0032387	negative regulation of intracellular transport	15/2112	67/18670	0.006979	0.03826	0.02764	ANGPT1/ITGB1BP1/LGALS9/CRYAB/CD36/TPR/BARD1/IL13RA2/PLN/GDI1/ADIPOQ/MAP1B/UBE2J1/FERMT1/UBE2G2	15
BP	GO:0003015	heart process	47/2112	290/18670	0.007137	0.03907	0.02823	GCH1/CXCR4/SRI/SEMA3A/CACNA2D1/ANK2/KCNK1/NPR2/FXYD1/JAK2/FXYD6/HDAC4/YAP1/HBEGF/ADA/KCNJ5/TAC1/ADORA3/AHCYL1/PLN/ASPH/NOX4/SOD1/SGCD/KCNJ2/TRPC1/ATP1B1/SCN1B/IRX5/KCNJ8/DSC2/ATP1A2/PIK3CA/HEY2/SLC8A1/POPDC2/WWTR1/AKAP13/RYR3/VEGFB/GSTO1/GJC1/GSTM2/SNTA1/THRA/GPD1L/ATP2A3	47
BP	GO:0007517	muscle organ development	63/2112	410/18670	0.00714	0.03907	0.02823	SGCB/BMP4/IGF1/HLF/SRI/PIM1/FOXC1/SKI/PPP3CA/CDON/SGCA/MEIS1/ZFHX3/HIVEP3/ZFPM2/LAMA2/SIX1/BMPR1A/CRYAB/HDAC4/SHOX2/YAP1/CXCL10/HBEGF/FGF2/TGFBR3/DCN/FHL1/CDK1/KCNK2/SGCE/ID3/EPHB1/TAGLN/SGCD/PITX1/LEF1/SMAD3/FZD7/RBP4/NOTCH1/ARNTL/PAX5/CCNB1/HEY2/PAK1/POPDC2/ITGB1BP2/FGF9/CTF1/HOXD10/CENPF/CHODL/JARID2/RB1/KCNAB1/MYLK/CD164/CFLAR/MYL6B/S1PR1/FZD2/TEAD4	63
BP	GO:0071349	cellular response to interleukin-12	12/2112	49/18670	0.007225	0.0395	0.02854	LCP1/LMNB1/JAK2/STAT4/HNRNPDL/SOD1/IFNG/CFL1/CAPZA1/GSTO1/TALDO1/TYK2	12
BP	GO:0043030	regulation of macrophage activation	13/2112	55/18670	0.007253	0.03955	0.02857	PTPRC/CST7/CD200/CD74/IL4R/TNIP2/CTSC/SPHK1/MFHAS1/IL6/NR1H3/CEBPA/TLR6	13
BP	GO:0045620	negative regulation of lymphocyte differentiation	13/2112	55/18670	0.007253	0.03955	0.02857	SFRP1/CTLA4/BMP4/IRF1/RUNX3/GLI3/INHBA/CD74/PTPN2/IL4R/SOCS1/ERBB2/TBX21	13
BP	GO:2000242	negative regulation of reproductive process	13/2112	55/18670	0.007253	0.03955	0.02857	BMP4/IGF1/ARHGDIB/NPR2/SULF1/ZFPM2/ADA/HPGDS/FBXO5/TTK/OVGP1/TRIP13/EAF2	13
BP	GO:0042136	neurotransmitter biosynthetic process	21/2112	106/18670	0.007275	0.0396	0.02861	CLU/GCH1/NQO1/HBB/ITGB2/ICAM1/JAK2/CD36/DDAH2/SLC1A3/CLEC7A/CX3CR1/SMAD3/IFNG/RGN/HSP90AB1/GLA/PKD2/TLR6/IL1B/PTX3	21
BP	GO:1901989	positive regulation of cell cycle phase transition	21/2112	106/18670	0.007275	0.0396	0.02861	DTL/CCND2/UBE2C/EGFR/CDC45/CDC25B/SMARCD3/CDK1/DLGAP5/EZH2/PBX1/HYAL1/BRD4/CDC7/CCNB1/MECP2/CCND1/FBXO5/PAF1/RB1/CUL4B	21
BP	GO:0006869	lipid transport	57/2112	365/18670	0.007295	0.03964	0.02864	PLA2G2D/LRP6/CLU/APOL1/SERPINA5/INHBA/ABCG1/SIGMAR1/ABCC4/APOL6/AQP9/CD36/APOL3/ATP8B2/ATP8A1/ATP9A/AKR1C1/NPC1/TAC1/GULP1/NMB/NFKBIA/PLA2G12A/ACACB/NFKB1/FZD4/ABCA8/PTPN11/RBP4/LIPG/LEP/STARD5/AGTR1/ADIPOQ/SYK/LRP10/CETP/PITPNC1/SCARB2/HDLBP/NR1H3/OSBPL1A/FABP4/STARD7/SLC27A5/APOLD1/OSBPL9/ABCA3/NME4/REN/SLCO1C1/UGCG/LIPC/ITGAV/STOML1/IL1B/SOAT2	57
BP	GO:0032102	negative regulation of response to external stimulus	57/2112	365/18670	0.007295	0.03964	0.02864	CXCL13/SLAMF8/PTPRC/TNFAIP3/IGF1/SEMA4A/NT5E/TNFRSF1B/CST7/SEMA4D/SEMA3A/CD200/PTPN2/HTRA1/KANK2/MICB/ADA/TSPAN6/PROS1/FGF2/GPR18/HGF/PLAT/SOD1/RYK/C5orf30/PTPRS/NFKB1/SEMA3F/SMAD3/MFHAS1/CD9/NOTCH1/LEP/NBL1/PTGER4/ADIPOQ/BACE1/PRKG1/TRIM38/SEMA4F/NR1H3/FPR2/RB1/SEMA3E/TFPI/SH2B3/DVL1/GP1BA/SEMA6B/SPINK5/PBK/IL2RA/CCL2/CASK/CDH5/NLRP3	57
BP	GO:0019336	phenol-containing compound catabolic process	5/2112	12/18670	0.007365	0.03967	0.02866	FAH/DIO2/MAOA/MAOB/DIO3	5
BP	GO:0033197	response to vitamin E	5/2112	12/18670	0.007365	0.03967	0.02866	ADA/LEP/CCND1/CAT/ALAD	5
BP	GO:0038110	interleukin-2-mediated signaling pathway	5/2112	12/18670	0.007365	0.03967	0.02866	IL2RG/IL2RB/PTPN2/SYK/IL2RA	5
BP	GO:0045579	positive regulation of B cell differentiation	5/2112	12/18670	0.007365	0.03967	0.02866	CD27/NCKAP1L/SYK/BTK/INPP5D	5
BP	GO:0060368	regulation of Fc receptor mediated stimulatory signaling pathway	5/2112	12/18670	0.007365	0.03967	0.02866	PTPRC/CSK/CD226/PLSCR1/LYN	5
BP	GO:0060391	positive regulation of SMAD protein signal transduction	5/2112	12/18670	0.007365	0.03967	0.02866	BMP4/BMPR1A/NUP93/PARP1/TGFB3	5
BP	GO:0071639	positive regulation of monocyte chemotactic protein-1 production	5/2112	12/18670	0.007365	0.03967	0.02866	LGALS9/CLEC7A/ADIPOQ/SYK/IL1B	5
BP	GO:0071888	macrophage apoptotic process	5/2112	12/18670	0.007365	0.03967	0.02866	CCL5/CCR5/NOD2/IRF7/CTSL	5
BP	GO:0098885	modification of postsynaptic actin cytoskeleton	5/2112	12/18670	0.007365	0.03967	0.02866	WASF3/MYH10/PFN2/ITSN1/PFN1	5
BP	GO:1904668	positive regulation of ubiquitin protein ligase activity	5/2112	12/18670	0.007365	0.03967	0.02866	UBE2C/GOLGA2/PLK1/CDC14B/CDC20	5
BP	GO:0008608	attachment of spindle microtubules to kinetochore	9/2112	32/18670	0.00742	0.03983	0.02877	NDC80/ZNF207/KIF2C/NEK2/RACGAP1/ECT2/CCNB1/AURKB/RB1	9
BP	GO:0032814	regulation of natural killer cell activation	9/2112	32/18670	0.00742	0.03983	0.02877	RASGRP1/HLA-F/IL15/AXL/HLA-E/TOX/LEP/PTPN22/IL18	9
BP	GO:0048841	regulation of axon extension involved in axon guidance	9/2112	32/18670	0.00742	0.03983	0.02877	SEMA4A/SEMA4D/SEMA3A/RYK/SEMA3F/MEGF8/SEMA4F/SEMA3E/SEMA6B	9
BP	GO:0033273	response to vitamin	19/2112	93/18670	0.00742	0.03983	0.02877	SFRP1/PENK/IL15/PIM1/KYNU/KANK2/CXCL10/TRIM24/EGFR/ADA/PTN/LEP/ALPL/CCND1/MAP1B/TYMS/CAT/ALAD/GSN	19
BP	GO:1901657	glycosyl compound metabolic process	27/2112	147/18670	0.007488	0.04016	0.02901	AMPD3/TYMP/NT5E/AKR1C3/UPP1/ADK/APOBEC3G/APOBEC3B/AKR1B1/NME7/ADA/AKR1C1/AHCYL1/MACROD1/MOCS2/FUCA1/PNP/MBIP/AHCYL2/GLA/ENTPD4/NME4/TK2/TK1/CASK/AKR7A2/PRPS2	27
BP	GO:0046165	alcohol biosynthetic process	31/2112	175/18670	0.007533	0.04031	0.02913	LBR/GCH1/PLCE1/ABCG1/PMVK/PCBD1/AKR1B1/CYB5R3/FGF2/SPHK1/PLCG2/PLEK/ERLIN1/SP1/PCK1/SOD1/ACACB/NFKB1/SC5D/HRH1/LEP/IFNG/NFYA/P2RY6/ERLIN2/GFI1/PPIP5K1/MBTPS2/DKK3/PTH1R/IL1B	31
BP	GO:0061025	membrane fusion	28/2112	154/18670	0.007534	0.04031	0.02913	CCR5/TAP1/TAPBP/CORO1A/CXCR4/GCA/SERPINA5/TAP2/RAB8A/MX2/LRMP/DYSF/SPHK1/SAMD9/VCPIP1/STX16/VPS16/RAB20/CD9/STX18/STX4/VAMP2/STXBP1/CHMP2B/MX1/STX6/VTI1B/VAV3	28
BP	GO:0046620	regulation of organ growth	22/2112	113/18670	0.007537	0.04031	0.02913	IGF1/PIM1/FOXC1/MEIS1/SASH3/ZFPM2/BMPR1A/YAP1/FGF2/TGFBR3/CDK1/KCNK2/SOD1/ACACB/RBP4/NOTCH1/CCNB1/HEY2/PAK1/FGF9/DUSP6/JARID2	22
BP	GO:0034614	cellular response to reactive oxygen species	30/2112	168/18670	0.007554	0.04037	0.02917	PLEKHA1/TNFAIP3/GCH1/NQO1/AKR1C3/AXL/SIGMAR1/CD36/PDGFD/EGFR/FBLN5/SPHK1/CDK1/HGF/CCNA2/EZH2/SOD1/MAPK13/FOXO1/NET1/ECT2/RGN/PINK1/BTK/IL6/FER/FOXO3/PKD2/CFLAR/NCF1	30
BP	GO:0014015	positive regulation of gliogenesis	16/2112	74/18670	0.007716	0.0412	0.02977	CCR2/PRKCH/TNFRSF1B/CXCR4/ZNF365/TLR2/DAG1/ETV5/ASPA/PTN/NOTCH1/IL6ST/IL6/LYN/TENM4/IL1B	16
BP	GO:0006470	protein dephosphorylation	51/2112	321/18670	0.007729	0.04123	0.02979	LCK/PTPRC/PPP1R3C/PTPN14/EYA4/LILRB2/PTPRE/PPP2CA/PPP3CA/DUSP5/PTPN2/EYA2/PTPRD/JAK2/PTPN7/CDC14B/PTPN6/DLC1/CDC25B/RPAP2/PHACTR2/DLGAP5/MAGI2/MTMR14/PPP1R16B/PTPRF/PTN/NCKAP1L/PPP4C/PPP2CB/PTPRS/PTPN11/PTPN13/MFHAS1/PPP1CA/RGN/PPM1F/HSP90AB1/PHLPP1/PINK1/PTPN22/DUSP6/SSH3/DUSP2/RPRD1A/ENSA/PPP1R11/DAPP1/CAMTA1/MTMR2/CDH5	51
BP	GO:0072089	stem cell proliferation	23/2112	120/18670	0.00775	0.04131	0.02985	KITLG/PTPRC/ASPM/PIM1/GLI3/LTBP3/SOX5/EML1/SIX2/YAP1/FGF2/FGF13/SMARCD3/CX3CR1/PTN/LEF1/ETV6/RACGAP1/NOTCH1/ZFP36L1/FBLN1/FERMT1/TP53	23
BP	GO:0061640	cytoskeleton-dependent cytokinesis	20/2112	100/18670	0.007797	0.04149	0.02998	MYH10/NUSAP1/PLK1/CKAP2/CEP55/MAP9/KIF4A/KIF20A/RACGAP1/ECT2/CHMP2B/CFL1/AURKB/KIF20B/ARL3/ACTR3/SPTBN1/ACTR2/CHMP1B/KIF23	20
BP	GO:0070498	interleukin-1-mediated signaling pathway	20/2112	100/18670	0.007797	0.04149	0.02998	PSMB9/PSMB8/PSMB10/MYD88/VRK2/SKP1/NOD2/TNIP2/MAP3K8/PSME1/RIPK2/NFKBIA/RPS6KA4/NFKB1/IKBKG/IL6/IL1RN/NOD1/IL1R1/IL1B	20
BP	GO:0016358	dendrite development	39/2112	233/18670	0.007952	0.04228	0.03055	CD3E/RBFOX2/DLG5/SEMA4D/DOCK10/SEMA3A/PPP3CA/LPAR1/ZNF365/PTPRD/TRAK2/ITSN1/COBL/WASL/KLF7/NLGN1/EZH2/SCARF1/EPHB1/CAMK1D/PTN/PDLIM5/PTPRS/PLK2/MECP2/CAMSAP2/MARK1/MAP1B/PRKG1/BCL11A/LST1/CFL1/ADAM10/CDC20/DVL1/ABI2/FEZF2/ACTR2/DCLK1	39
BP	GO:1901021	positive regulation of calcium ion transmembrane transporter activity	10/2112	38/18670	0.008086	0.04295	0.03103	CACNA2D1/ANK2/PLCG2/ATP1B1/RGN/FGF14/P2RY6/PKD2/GSTO1/GSTM2	10
BP	GO:0048524	positive regulation of viral process	21/2112	107/18670	0.008112	0.04305	0.03111	CCL5/NUCKS1/CD74/CHD1/LGALS9/PC/SRPK1/CCNT1/SP1/TOP2A/LEF1/TRIM21/NOTCH1/GTF2F1/ADAR/POLR2L/TRIM38/CHMP2B/CFL1/KPNA2/RSF1	21
BP	GO:0022616	DNA strand elongation	8/2112	27/18670	0.00814	0.04305	0.03111	LIG1/NUCKS1/RFC3/GINS1/FEN1/RNASEH2A/MCM4/GINS3	8
BP	GO:0045671	negative regulation of osteoclast differentiation	8/2112	27/18670	0.00814	0.04305	0.03111	PIK3R1/SFRP1/LILRB3/LILRB4/INPP5D/FSTL3/TOB2/LILRB1	8
BP	GO:0061437	renal system vasculature development	8/2112	27/18670	0.00814	0.04305	0.03111	BMP4/ANGPT1/PDGFD/NOTCH1/PECAM1/PKD2/CFLAR/GPR4	8
BP	GO:0061440	kidney vasculature development	8/2112	27/18670	0.00814	0.04305	0.03111	BMP4/ANGPT1/PDGFD/NOTCH1/PECAM1/PKD2/CFLAR/GPR4	8
BP	GO:0006986	response to unfolded protein	31/2112	176/18670	0.008179	0.0432	0.03122	PIK3R1/ACADVL/PTPN2/EXTL2/COMP/TM7SF3/THBS4/HSPA6/CXCL8/SEC31A/CREB3L2/BAK1/TSPYL2/HSPA4L/EDEM1/KDELR3/VCP/GFPT1/FKBP14/HSP90AB1/CCND1/HSPB1/DDIT3/LMNA/MBTPS2/HSPA1L/EDEM2/DNAJB4/HSPB2/TATDN2/CCL2	31
BP	GO:0007548	sex differentiation	44/2112	270/18670	0.008182	0.0432	0.03122	KITLG/PLEKHA1/SFRP1/LRP6/ASPM/HOXA10/SOX9/FOXC1/SEMA3A/INHBA/AKR1C3/RHOBTB3/AXL/TNFSF10/AR/ZFPM2/SGPL1/ICAM1/BMPR1A/TCF7/BAK1/TP63/SOD1/PBX1/BCL2L2/FZD4/PTPN11/ATRX/RBP4/IRX5/LEP/CCND1/FGF9/NIPBL/REC8/FOXO3/ANG/FSTL3/MERTK/REN/ERCC1/HOXA11/NRIP1/PTX3	44
BP	GO:0010977	negative regulation of neuron projection development	28/2112	155/18670	0.008229	0.04338	0.03134	SEMA4A/SEMA4D/SEMA3A/PPP3CA/SPOCK1/LPAR1/ZNF365/GAK/TRAK2/PMP22/FGF13/NLGN1/RYK/PTPRS/SEMA3F/PLK2/GDI1/KANK1/MYLIP/DPYSL3/GFI1/ARHGAP4/CD38/BCL11A/SEMA4F/SEMA3E/BAG5/SEMA6B	28
BP	GO:1902652	secondary alcohol metabolic process	28/2112	155/18670	0.008229	0.04338	0.03134	LBR/APOL1/ACADVL/ABCG1/NFE2L1/PMVK/CYB5R3/NPC1/ERLIN1/SP1/SCARF1/SOD1/ACACB/SC5D/LEP/NFYA/ERLIN2/CETP/HDLBP/OSBPL1A/MBTPS2/CYP46A1/CEBPA/ACADL/CAT/LIPC/EPHX2/SOAT2	28
BP	GO:0007045	cell-substrate adherens junction assembly	17/2112	81/18670	0.008353	0.04391	0.03173	SFRP1/EPHA3/LIMCH1/ITGB1BP1/FERMT2/DLC1/EFNA5/SMAD3/CORO2B/MYOC/PPM1F/TRIP6/SORBS1/CTTN/RHOD/KDR/COL16A1	17
BP	GO:0014032	neural crest cell development	17/2112	81/18670	0.008353	0.04391	0.03173	KITLG/BMP4/SEMA4A/SOX9/SEMA4D/FOXC1/SEMA3A/BMPR1A/HTR2B/FAM172A/SEMA3F/ACVR1/EDNRB/CFL1/SEMA4F/SEMA3E/SEMA6B	17
BP	GO:0048041	focal adhesion assembly	17/2112	81/18670	0.008353	0.04391	0.03173	SFRP1/EPHA3/LIMCH1/ITGB1BP1/FERMT2/DLC1/EFNA5/SMAD3/CORO2B/MYOC/PPM1F/TRIP6/SORBS1/CTTN/RHOD/KDR/COL16A1	17
BP	GO:0014003	oligodendrocyte development	11/2112	44/18670	0.008437	0.04424	0.03197	WASF3/CLU/PLP1/LPAR1/TLR2/ASPA/FA2H/CD9/LYN/TENM4/GSN	11
BP	GO:0061756	leukocyte adhesion to vascular endothelial cell	11/2112	44/18670	0.008437	0.04424	0.03197	CCR2/ITGB7/ITGA4/ITGB2/ICAM1/SELL/SELE/CCL21/CX3CR1/LEP/SELPLG	11
BP	GO:1902667	regulation of axon guidance	11/2112	44/18670	0.008437	0.04424	0.03197	SEMA4A/SEMA4D/SEMA3A/TUBB2B/RYK/SEMA3F/MEGF8/SEMA4F/SEMA3E/SEMA6B/FEZF2	11
BP	GO:0002693	positive regulation of cellular extravasation	6/2112	17/18670	0.008533	0.04453	0.03217	CCR2/ITGA4/ICAM1/ADAM8/PDGFD/IL1R1	6
BP	GO:0007076	mitotic chromosome condensation	6/2112	17/18670	0.008533	0.04453	0.03217	NUSAP1/NCAPD2/NCAPH/NCAPG/NIPBL/SMC4	6
BP	GO:0033145	positive regulation of intracellular steroid hormone receptor signaling pathway	6/2112	17/18670	0.008533	0.04453	0.03217	LMO3/AR/YAP1/PAK1/PARP1/RWDD1	6
BP	GO:0051709	regulation of killing of cells of other organism	6/2112	17/18670	0.008533	0.04453	0.03217	PRF1/CLEC7A/IFNG/KRT6A/SYK/CXCL6	6
BP	GO:0070242	thymocyte apoptotic process	6/2112	17/18670	0.008533	0.04453	0.03217	BMP4/GLI3/ADAM8/ADA/BAK1/TP53	6
BP	GO:0099010	modification of postsynaptic structure	6/2112	17/18670	0.008533	0.04453	0.03217	WASF3/MYH10/PFN2/ITSN1/CHMP2B/PFN1	6
BP	GO:0014009	glial cell proliferation	12/2112	50/18670	0.00855	0.04454	0.03218	PRKCH/PENK/CLU/SKI/ETV5/IDH2/PTN/NOTCH1/IL6/LYN/RNF10/IL1B	12
BP	GO:0046854	phosphatidylinositol phosphorylation	12/2112	50/18670	0.00855	0.04454	0.03218	PIK3R1/PIP4K2B/SOCS1/CISH/SOCS2/PIK3CD/INPP1/SOCS6/PIK3CA/PIK3R3/PIP4K2A/BPNT1	12
BP	GO:0046890	regulation of lipid biosynthetic process	34/2112	198/18670	0.008605	0.0446	0.03222	ZBTB20/AKR1C3/ACADVL/ABCG1/CD74/PMVK/HTR2B/SPHK1/SIK1/ERLIN1/SP1/SOD1/ACACB/NFKB1/HTR2A/SC5D/LEP/IFNG/RGN/NFYA/ADIPOQ/ERLIN2/FABP5/GFI1/PDK4/SORBS1/NR1H3/FPR2/MBTPS2/ABHD6/ACADL/DKK3/IL1B/ELOVL5	34
BP	GO:0006925	inflammatory cell apoptotic process	7/2112	22/18670	0.008613	0.0446	0.03222	CCL5/CCR5/NOD2/IRF7/CTSL/PIK3CD/IL6	7
BP	GO:0032727	positive regulation of interferon-alpha production	7/2112	22/18670	0.008613	0.0446	0.03222	TLR8/STAT1/IRF7/IFIH1/RIPK2/DDX58/MMP12	7
BP	GO:0032928	regulation of superoxide anion generation	7/2112	22/18670	0.008613	0.0446	0.03222	ITGB2/EGFR/CLEC7A/SOD1/SYK/FPR2/CYBA	7
BP	GO:0048305	immunoglobulin secretion	7/2112	22/18670	0.008613	0.0446	0.03222	CD40/HLA-E/CD40LG/RBP4/STX4/TNFRSF4/IL6	7
BP	GO:1901685	glutathione derivative metabolic process	7/2112	22/18670	0.008613	0.0446	0.03222	GSTM5/GSTM3/GSTA4/ESD/HPGDS/GSTO1/GSTM2	7
BP	GO:1901687	glutathione derivative biosynthetic process	7/2112	22/18670	0.008613	0.0446	0.03222	GSTM5/GSTM3/GSTA4/ESD/HPGDS/GSTO1/GSTM2	7
BP	GO:0019318	hexose metabolic process	41/2112	249/18670	0.008763	0.04534	0.03276	ENPP1/IGF1/GALT/NPY1R/CHST15/NFE2L1/PTPN2/OAS1/AKR1B1/HK3/ALDOC/PC/PASK/SIK1/PCK1/PER2/LRP5/COX11/ACACB/FAM3C/PMAIP1/FOXO1/RBP4/LEP/PPP1CA/RGN/PIK3CA/FUCA1/ADIPOQ/FABP5/PDK4/SORBS1/MDH1/MAN2B1/MAN2A2/FUT8/TP53/SLC35A2/TKTL1/FUT4/ALDH5A1	41
BP	GO:0060249	anatomical structure homeostasis	66/2112	437/18670	0.008815	0.04557	0.03293	TNFAIP3/CCR2/TNFRSF11B/CORO1A/CSK/RAC2/PRKCQ/SERPINA3/SOX9/LTBP3/FOXC1/ZNF365/SASH3/TCIRG1/NOD2/ADAM8/SMC6/LYZ/YAP1/GATA2/AKR1B1/TFRC/EGFR/BLM/BARD1/NOX4/NEK7/RFC3/SOD1/NEK2/FEN1/PTPN11/CA2/ATRX/RBP4/NELL2/NOTCH1/TERF1/HSP90AB1/SYK/BBS1/PDK4/PARP1/HSPB1/WWTR1/AKT3/IL6/CD38/INPP5D/RCN3/CHMP2B/POLE2/FGGY/AURKB/RB1/SNX10/ERCC1/S1PR1/PTH1R/USP7/CCNE2/NPHP4/PARN/P2RY4/PML/CTSH	66
BP	GO:0050871	positive regulation of B cell activation	26/2112	142/18670	0.00892	0.04607	0.03329	TRBC1/PTPRC/GPR183/SASH3/CD74/NOD2/TNIP2/CD40/TFRC/ADA/IGHM/IGLL5/TBX21/CD27/NCKAP1L/IGLC1/SYK/BTK/TNFRSF4/IL6/CD38/IGHG1/INPP5D/CD320/CD81/VAV3	26
BP	GO:0048592	eye morphogenesis	27/2112	149/18670	0.008963	0.04626	0.03342	BMP4/LRP6/SOX9/GLI3/NTRK2/TSKU/SKI/CDON/MEIS1/COL8A2/COL8A1/BAK1/EPHB1/PTN/LRP5/EFEMP1/RBP4/IRX5/TFAP2A/NIPBL/ZHX2/HIPK2/DIO3/ROM1/ABI2/CRYGB/AHI1	27
BP	GO:0048634	regulation of muscle organ development	28/2112	156/18670	0.008976	0.04629	0.03344	BMP4/IGF1/PIM1/CDON/MEIS1/ZFPM2/SIX1/BMPR1A/HDAC4/SHOX2/YAP1/FGF2/TGFBR3/CDK1/KCNK2/EPHB1/LEF1/SMAD3/FZD7/RBP4/NOTCH1/ARNTL/CCNB1/HEY2/PAK1/FGF9/CENPF/JARID2	28
BP	GO:0050718	positive regulation of interleukin-1 beta secretion	9/2112	33/18670	0.009199	0.04732	0.03419	AIM2/TLR8/CCL19/LGALS9/NOD2/RIPK2/CASP1/PANX1/NLRP3	9
BP	GO:0061036	positive regulation of cartilage development	9/2112	33/18670	0.009199	0.04732	0.03419	GDF5/BMP4/FGF18/SOX9/ZBTB16/GLI3/SOX5/SMAD3/HOXA11	9
BP	GO:2000352	negative regulation of endothelial cell apoptotic process	9/2112	33/18670	0.009199	0.04732	0.03419	NDNF/TNFAIP3/ANGPT1/ICAM1/TNIP2/SCG2/GATA2/ANGPTL4/KDR	9
BP	GO:0030166	proteoglycan biosynthetic process	15/2112	69/18670	0.009227	0.04742	0.03426	IGF1/CHST15/EXTL2/CHST3/DCN/BGN/CSPG4/TCF7L2/GAL3ST4/CHST11/VCAN/FAM20B/UGDH/EXT2/CANT1	15
BP	GO:0006023	aminoglycan biosynthetic process	22/2112	115/18670	0.009272	0.04761	0.0344	PRELP/FMOD/GPC5/OGN/CHST15/ANGPT1/EXTL2/CHST3/DCN/BGN/CSPG4/CHST11/LUM/NFKB1/VCAN/HYAL1/UGDH/GPC4/EXT2/B3GNT2/IL1B/B4GALT2	22
BP	GO:0017038	protein import	34/2112	199/18670	0.009281	0.04762	0.03441	PIK3R1/BMP4/ZIC1/CLU/GLI3/PPP3CA/ANGPT1/HCLS1/PEX26/CD36/NUP93/SIX2/TPR/NFKBIA/NDUFA13/ZPR1/SMAD3/ARNTL/ECT2/LEP/IFNG/SYK/FGF9/PEX19/IPO7/KPNA2/LMNA/FERMT1/NUP88/NUP50/TP53/HEATR3/MMP12/PML	34
BP	GO:1903578	regulation of ATP metabolic process	23/2112	122/18670	0.009463	0.04852	0.03505	PID1/IGF1/ZBTB20/SLC2A6/CBFA2T3/COX7A1/NUP93/HDAC4/TPR/CDK1/NUP160/HTR2A/VCP/IFNG/ARNT/CCNB1/PARP1/SLC25A23/PINK1/NUP88/NUP50/TP53/COX7A2	23
BP	GO:0042692	muscle cell differentiation	59/2112	385/18670	0.009502	0.04868	0.03517	CXCL9/SGCB/BMP4/UCHL1/IGFBP5/IGF1/PLEKHO1/MYH10/SOX9/TMOD1/SKI/ANK2/PPP3CA/CDON/CBY1/IL4R/SIX1/DYSF/HDAC4/COMP/SHOX2/CXCL10/SMARCD3/CDK1/SIK1/EZH2/SORBS2/PDLIM5/NOX4/AFG3L2/CDH2/SGCD/CD53/DNMT1/CEACAM5/BHLHE41/FZD7/CD9/NOTCH1/LMOD1/CCNB1/MECP2/HEY2/SLC8A1/PAK1/POPDC2/ACVR1/EDNRB/FGF9/KRT19/AKAP13/MYH11/LMNA/RB1/HEY1/CD81/WDR1/CFLAR/ALPK3	59
BP	GO:1902275	regulation of chromatin organization	32/2112	185/18670	0.009515	0.0487	0.03519	NAP1L2/SKI/MKI67/AUTS2/PRKD2/GATA2/UBE2B/CDC45/KMT2A/TAF7/TPR/RPS6KA4/DNMT1/ATRX/BRD4/PAX5/CCNB1/EID1/MECP2/MTF2/MPHOSPH8/GFI1/SPI1/NIPBL/PAF1/PINK1/JARID2/LMNA/PRKD1/HMGA1/TP53/IL1B	32
BP	GO:0050808	synapse organization	62/2112	408/18670	0.009564	0.04891	0.03534	WASF3/SEMA4A/DLG5/LILRB2/PCDHB3/SPOCK2/MYH10/SEMA4D/DOCK10/NTRK2/ZNF365/TLR2/GLRB/PFN2/PTPRD/SIX1/ITSN1/WASL/PCDHB13/DAG1/ETV5/PCDHB11/ERBB2/MAGI2/ARHGAP22/NLGN1/CX3CR1/CLSTN1/EPHB1/PTPRF/PCDH17/PTN/PDLIM5/AFG3L2/CDH2/RYK/PTPRS/SEMA3F/EFNA5/VCP/PCDHGC3/MECP2/IL10RA/GPC4/CTTN/MAP1B/SYBU/SNCG/CHMP2B/CFL1/LRRN3/SEMA3E/ADAM10/CDC20/DVL1/WASF2/ABI2/PCDHB6/MTMR2/DRP2/PFN1/ACTR2	62
BP	GO:0046622	positive regulation of organ growth	14/2112	63/18670	0.009598	0.04904	0.03544	IGF1/PIM1/SASH3/ZFPM2/BMPR1A/YAP1/FGF2/TGFBR3/CDK1/ACACB/NOTCH1/CCNB1/HEY2/FGF9	14
BP	GO:0016051	carbohydrate biosynthetic process	36/2112	214/18670	0.009678	0.04941	0.0357	ENPP1/IGF1/PPP1R3C/CHST15/PTPN2/EXTL2/B3GALNT1/AKR1B1/ALDOC/PC/PASK/PLEK/SIK1/PCK1/CHST11/PER2/FAM3C/NFKB1/PGD/FOXO1/HRH1/RBP4/NANS/LEP/PPP1CA/RGN/ADIPOQ/P2RY6/SORBS1/EXT2/B3GNT2/MDH1/UGP2/FUT8/PTH1R/TALDO1	36
BP	GO:0023061	signal release	69/2112	462/18670	0.009687	0.04942	0.03571	CCL5/SFRP1/SRI/PREPL/INHBA/OXCT1/MCTP1/PPP3CA/PRKCB/PFN2/TCIRG1/WLS/JAK2/ITSN1/SLC18A2/SNCAIP/EGFR/KLF7/TM7SF3/TAC1/PASK/MPC2/NMB/CYB5R4/TCF7L2/NLGN1/PER2/LRP5/FZD4/HTR2A/CPE/CHRNA5/EFNA5/PTPN11/RBP4/ARNTL/SLC25A4/LEP/SSTR5/AGTR1/IFNG/KMO/SYT17/ADIPOQ/STX4/VAMP2/STXBP1/HFE/BACE1/BTK/IL6/CD38/SYBU/SNCG/ENSA/IL1RN/SLC25A5/LYN/NAAA/DVL1/REN/HADH/RAB11FIP2/CASK/IL1B/P2RY4/RAB11FIP1/CADPS/GPR27	69
BP	GO:0098869	cellular oxidant detoxification	20/2112	102/18670	0.00972	0.04954	0.0358	S100A9/GCH1/NQO1/LTC4S/HBB/CD36/FBLN5/SOD1/GPX3/IPCEF1/GPX4/HBD/RGN/PRDX6/PTGS1/HP/SESN1/GSTO1/CAT/GSTM2	20
BP	GO:0035821	modification of morphology or physiology of other organism	29/2112	164/18670	0.009744	0.04963	0.03586	CCL5/S100A9/PRF1/APOL1/SLPI/NUCKS1/CCL13/CHD1/GNLY/LYZ/DAG1/PC/CLEC7A/IFI27/CCNT1/SP1/LEF1/SMAD3/FBXL2/IFNG/KRT6A/SYK/TYMS/CFL1/KPNA2/CXCL6/HIPK2/ITGAV/PTX3	29
BP	GO:1904591	positive regulation of protein import	10/2112	39/18670	0.009797	0.04985	0.03602	PIK3R1/ZIC1/GLI3/HCLS1/TPR/ZPR1/SMAD3/ECT2/LEP/IFNG	10
BP	GO:0001755	neural crest cell migration	13/2112	57/18670	0.009888	0.05028	0.03633	KITLG/BMP4/SEMA4A/SEMA4D/SEMA3A/HTR2B/SEMA3F/ACVR1/EDNRB/CFL1/SEMA4F/SEMA3E/SEMA6B	13
BP	GO:0014897	striated muscle hypertrophy	21/2112	109/18670	0.01002	0.0508	0.03671	IGFBP5/IGF1/TNFRSF1B/PPP3CA/HDAC4/HTR2B/EZH2/SORBS2/PDLIM5/FOXO1/SMAD3/NOTCH1/MYOC/LEP/IL6ST/HEY2/PAK1/PARP1/AKAP13/JARID2/LMNA	21
BP	GO:0045581	negative regulation of T cell differentiation	11/2112	45/18670	0.01005	0.0508	0.03671	CTLA4/BMP4/IRF1/RUNX3/GLI3/CD74/PTPN2/IL4R/SOCS1/ERBB2/TBX21	11
BP	GO:0048701	embryonic cranial skeleton morphogenesis	11/2112	45/18670	0.01005	0.0508	0.03671	BMP4/SIX1/SIX2/CHST11/SMAD3/IRX5/PAX5/TFAP2A/TGFB3/NIPBL/TULP3	11
BP	GO:0002712	regulation of B cell mediated immunity	12/2112	51/18670	0.01006	0.0508	0.03671	XCL1/PTPRC/IL27RA/CD40/TFRC/HLA-E/PTPN6/CR1/CD226/TBX21/BTK/THOC1	12
BP	GO:0002889	regulation of immunoglobulin mediated immune response	12/2112	51/18670	0.01006	0.0508	0.03671	XCL1/PTPRC/IL27RA/CD40/TFRC/HLA-E/PTPN6/CR1/CD226/TBX21/BTK/THOC1	12
BP	GO:0009994	oocyte differentiation	12/2112	51/18670	0.01006	0.0508	0.03671	IGF1/NPR2/CDC25B/DAZL/CCNB1/FBXO5/REC8/FOXO3/ANG/TRIP13/AURKA/YBX2	12
BP	GO:0045599	negative regulation of fat cell differentiation	12/2112	51/18670	0.01006	0.0508	0.03671	ENPP1/RUNX1T1/ZFPM2/GATA2/FOXO1/SMAD3/ARNTL/ADIPOQ/WWTR1/IL6/DDIT3/ZFP36L2	12
BP	GO:0048260	positive regulation of receptor-mediated endocytosis	12/2112	51/18670	0.01006	0.0508	0.03671	CLU/CCL19/ANGPT1/TBC1D5/WASL/SELE/PLCG2/CCL21/MAGI2/SYK/HFE/AHI1	12
BP	GO:0021987	cerebral cortex development	22/2112	116/18670	0.01025	0.05164	0.03731	LRP6/TACC3/GNG12/ASPM/BCL2A1/GLI3/NTRK2/SEMA3A/CDON/EGFR/FGF13/TACC1/CDH2/MCPH1/PTPRS/DIXDC1/TACC2/PAX5/FAT4/EMX2/POU3F3/MBOAT7	22
BP	GO:0022900	electron transport chain	32/2112	186/18670	0.01028	0.05164	0.03731	IDO1/NQO1/NDUFC1/NDUFA4L2/BID/NDUFS2/COX7A1/AKR1B1/NDUFS4/DHRS3/CDK1/SLC25A22/ASPH/NOX4/COX11/ETFB/NDUFA13/CCNB1/MECP2/PINK1/AOC2/NDUFA9/MAOB/ADH5/CYBA/SDHA/NDUFB6/NCF1/AKR7A2/NDUFA4/ALDH5A1/COX7A2	32
BP	GO:0030308	negative regulation of cell growth	32/2112	186/18670	0.01028	0.05164	0.03731	ENPP1/CDKN2C/SFRP1/SEMA4A/SIPA1/SEMA4D/SEMA3A/INHBA/PPP2CA/CRLF3/CRYAB/NDRG3/FHL1/FGF13/TSPYL2/NDUFA13/RYK/PTPRS/SEMA3F/HYAL1/SMAD3/SMARCA2/PAK1/ARHGAP4/BCL11A/SEMA4F/SEMA3E/SEMA6B/TP53/DCBLD2/EAF2/PML	32
BP	GO:0055001	muscle cell development	32/2112	186/18670	0.01028	0.05164	0.03731	SGCB/BMP4/UCHL1/IGF1/MYH10/TMOD1/SKI/ANK2/PPP3CA/SIX1/DYSF/HDAC4/COMP/SHOX2/CDK1/SORBS2/PDLIM5/AFG3L2/SGCD/NOTCH1/LMOD1/CCNB1/HEY2/SLC8A1/PAK1/KRT19/AKAP13/MYH11/LMNA/WDR1/CFLAR/ALPK3	32
BP	GO:0031440	regulation of mRNA 3'-end processing	8/2112	28/18670	0.01029	0.05164	0.03731	CPEB1/CPSF6/BARD1/CCNT1/AHCYL1/ZFP36L1/CCNB1/PAF1	8
BP	GO:0035456	response to interferon-beta	8/2112	28/18670	0.01029	0.05164	0.03731	AIM2/IRF1/STAT1/XAF1/NDUFA13/MNDA/PLSCR1/UBE2G2	8
BP	GO:0085029	extracellular matrix assembly	8/2112	28/18670	0.01029	0.05164	0.03731	SOX9/ANTXR1/MFAP4/EFEMP2/FBLN5/SMAD3/NOTCH1/MYH11	8
BP	GO:1902668	negative regulation of axon guidance	8/2112	28/18670	0.01029	0.05164	0.03731	SEMA4A/SEMA4D/SEMA3A/RYK/SEMA3F/SEMA4F/SEMA3E/SEMA6B	8
BP	GO:1990778	protein localization to cell periphery	49/2112	311/18670	0.01036	0.05193	0.03752	PID1/PIK3R1/EPHA3/GBP1/LRP6/EPB41L2/PRKCH/CSK/PREPL/RAB8A/ANK2/EMP2/ITGB1BP1/GAK/AR/PLK1/EGFR/DAG1/FGF13/CLSTN1/CDH2/DCHS1/SKAP1/ATP1B1/ADAM22/RHOG/IFNG/ADIPOQ/STX4/BBS1/GPC4/SORBS1/VAMP2/TSPAN14/STXBP1/LGI1/TESC/ADAM10/CLIP3/MPP5/BBIP1/CD81/ARL3/GOLGA7/VTI1B/RAB11FIP2/SPTBN1/KIF1B/PRKG2	49
BP	GO:0010517	regulation of phospholipase activity	15/2112	70/18670	0.01055	0.05276	0.03812	CCL5/ITK/ARL1/NTRK2/LPAR1/HTR2B/EGFR/FGF2/SELE/TXK/HTR2A/AGTR1/P2RY6/ANG/S1PR4	15
BP	GO:0060395	SMAD protein signal transduction	15/2112	70/18670	0.01055	0.05276	0.03812	GDF5/BMP4/SKI/INHBA/CILP/BMPR1A/NUP93/MAGI2/SMAD3/TOB1/PARP1/TGFB3/WWTR1/HIPK2/SPTBN1	15
BP	GO:0072091	regulation of stem cell proliferation	15/2112	70/18670	0.01055	0.05276	0.03812	KITLG/PTPRC/ASPM/PIM1/GLI3/LTBP3/YAP1/SMARCD3/CX3CR1/PTN/NOTCH1/ZFP36L1/FBLN1/FERMT1/TP53	15
BP	GO:0071322	cellular response to carbohydrate stimulus	26/2112	144/18670	0.01066	0.05327	0.03849	ZBTB20/SRI/OXCT1/PPP3CA/PRKCB/ICAM1/KLF7/CLEC7A/MPC2/PCK1/LRP5/NOX4/MAPK13/EFNA5/COLEC12/LEP/ZFP36L1/PIK3CA/STX4/SYBU/FOXO3/CYBA/RAB11FIP2/SLC2A5/ZNF236/GPR27	26
BP	GO:1903169	regulation of calcium ion transmembrane transport	27/2112	151/18670	0.01067	0.05327	0.03849	CXCL9/XCL1/CORO1A/SRI/CACNA2D1/ANK2/DYSF/GEM/CXCL10/PTPN6/PLCG2/PLN/TRPC1/CD19/ATP1B1/RGN/ATP1A2/CXCL11/SLC8A1/FGF14/P2RY6/APLNR/CYBA/LYN/PKD2/GSTO1/GSTM2	27
BP	GO:0032091	negative regulation of protein binding	20/2112	103/18670	0.01081	0.05358	0.03871	ITGA4/SLPI/ITGB1BP1/GOLGA2/BAG2/PTPRF/LRPAP1/LEF1/GTF2F1/PPP1CA/ADIPOQ/DACT1/HFE/AURKB/CRTAC1/DVL1/IFIT2/PIM2/CCL23/AURKA	20
BP	GO:1905269	positive regulation of chromatin organization	20/2112	103/18670	0.01081	0.05358	0.03871	NAP1L2/AUTS2/PRKD2/KMT2A/TPR/RPS6KA4/DNMT1/BRD4/CCNB1/MECP2/MTF2/MPHOSPH8/NIPBL/PAF1/PINK1/JARID2/LMNA/PRKD1/TP53/IL1B	20
BP	GO:0030205	dermatan sulfate metabolic process	5/2112	13/18670	0.01087	0.05358	0.03871	DCN/BGN/CSPG4/VCAN/IDUA	5
BP	GO:0031953	negative regulation of protein autophosphorylation	5/2112	13/18670	0.01087	0.05358	0.03871	ENPP1/PTPRC/ADIPOQ/GFRA2/MVP	5
BP	GO:0033623	regulation of integrin activation	5/2112	13/18670	0.01087	0.05358	0.03871	CXCL13/RASIP1/PLEK/SKAP1/PTGER4	5
BP	GO:0034214	protein hexamerization	5/2112	13/18670	0.01087	0.05358	0.03871	YME1L1/OAT/UGDH/VCP/PANX1	5
BP	GO:0034374	low-density lipoprotein particle remodeling	5/2112	13/18670	0.01087	0.05358	0.03871	ABCG1/AGTR1/CETP/LIPC/PLA2G7	5
BP	GO:0035745	T-helper 2 cell cytokine production	5/2112	13/18670	0.01087	0.05358	0.03871	XCL1/TBX21/IL6/CD81/NLRP3	5
BP	GO:0051451	myoblast migration	5/2112	13/18670	0.01087	0.05358	0.03871	PLEKHO1/ITGB1BP1/SIX1/THBS4/NET1	5
BP	GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	5/2112	13/18670	0.01087	0.05358	0.03871	TNFAIP3/NOD2/RIPK2/NFKBIA/PTPN22	5
BP	GO:0071352	cellular response to interleukin-2	5/2112	13/18670	0.01087	0.05358	0.03871	IL2RG/IL2RB/PTPN2/SYK/IL2RA	5
BP	GO:0099633	protein localization to postsynaptic specialization membrane	5/2112	13/18670	0.01087	0.05358	0.03871	DAG1/ADAM22/GPC4/LGI1/ADAM10	5
BP	GO:0099645	neurotransmitter receptor localization to postsynaptic specialization membrane	5/2112	13/18670	0.01087	0.05358	0.03871	DAG1/ADAM22/GPC4/LGI1/ADAM10	5
BP	GO:1902713	regulation of interferon-gamma secretion	5/2112	13/18670	0.01087	0.05358	0.03871	CD2/RASGRP1/LGALS9/CD160/PTPN22	5
BP	GO:1902894	negative regulation of pri-miRNA transcription by RNA polymerase II	5/2112	13/18670	0.01087	0.05358	0.03871	BMP4/SOX9/HDAC4/NFIB/LILRB4	5
BP	GO:1902947	regulation of tau-protein kinase activity	5/2112	13/18670	0.01087	0.05358	0.03871	CLU/HGF/IFNG/HSP90AB1/RB1	5
BP	GO:1903522	regulation of blood circulation	47/2112	297/18670	0.01097	0.05404	0.03904	GCH1/SRI/SEMA3A/CACNA2D1/ANK2/KCNK1/NPR2/FXYD1/ICAM1/JAK2/FXYD6/HDAC4/EGFR/HBEGF/ADA/KCNJ5/TAC1/ADORA3/FGF13/AHCYL1/PLN/ASPH/PER2/KCNJ2/TRPC1/HTR2A/ATP1B1/HRH1/SCN1B/IRX5/LEP/DSC2/AGTR1/ATP1A2/OR51E2/HEY2/SLC8A1/POPDC2/CD38/RYR3/GSTO1/GJC1/GSTM2/SNTA1/THRA/GPD1L/ATP2A3	47
BP	GO:0046579	positive regulation of Ras protein signal transduction	14/2112	64/18670	0.01104	0.05434	0.03926	KITLG/IGF1/RASGRP1/LPAR1/AUTS2/MAPRE2/JAK2/GPR18/VAV1/GPR65/NOTCH1/AKAP13/LYN/GPR4	14
BP	GO:0009595	detection of biotic stimulus	7/2112	23/18670	0.01119	0.05486	0.03964	TLR2/NOD2/CRTAM/CLEC7A/NOD1/TLR6/NLRP3	7
BP	GO:0043576	regulation of respiratory gaseous exchange	7/2112	23/18670	0.01119	0.05486	0.03964	FTO/PBX3/PASK/NLGN1/ATP1A2/MECP2/SLC5A3	7
BP	GO:0051043	regulation of membrane protein ectodomain proteolysis	7/2112	23/18670	0.01119	0.05486	0.03964	TIMP3/TNFRSF1B/TIMP4/ADAM8/TIMP2/IFNG/IL1B	7
BP	GO:0071305	cellular response to vitamin D	7/2112	23/18670	0.01119	0.05486	0.03964	SFRP1/PENK/IL15/PIM1/KANK2/TRIM24/PTN	7
BP	GO:0010717	regulation of epithelial to mesenchymal transition	18/2112	90/18670	0.01122	0.05486	0.03964	SFRP1/EPHA3/BMP4/FOXC1/PPP2CA/PDPN/DAG1/TCF7L2/EZH2/LEF1/SMAD3/LDLRAD4/NOTCH1/ACVR1/TGFB3/WWTR1/IL6/IL1B	18
BP	GO:0031058	positive regulation of histone modification	18/2112	90/18670	0.01122	0.05486	0.03964	NAP1L2/AUTS2/PRKD2/KMT2A/RPS6KA4/DNMT1/BRD4/CCNB1/MECP2/MTF2/NIPBL/PAF1/PINK1/JARID2/LMNA/PRKD1/TP53/IL1B	18
BP	GO:0034333	adherens junction assembly	18/2112	90/18670	0.01122	0.05486	0.03964	SFRP1/EPHA3/LIMCH1/DLG5/ITGB1BP1/FERMT2/DLC1/EFNA5/SMAD3/CORO2B/MYOC/PPM1F/TRIP6/SORBS1/CTTN/RHOD/KDR/COL16A1	18
BP	GO:0045132	meiotic chromosome segregation	18/2112	90/18670	0.01122	0.05486	0.03964	PTTG1/PTTG3P/BUB1/PLK1/UBE2B/NCAPH/BUB1B/TOP2A/RMI1/STAG3/TERF1/REC8/TTK/SMC4/ACTR3/TRIP13/CCNE2/ACTR2	18
BP	GO:0007435	salivary gland morphogenesis	9/2112	34/18670	0.01128	0.05506	0.03978	SEMA3A/FGF7/TWSG1/EGFR/DAG1/NFIB/HGF/TGFB3/TGM2	9
BP	GO:0043094	cellular metabolic compound salvage	9/2112	34/18670	0.01128	0.05506	0.03978	AMPD3/BHMT2/TYMP/UPP1/ADK/ADA/PNP/TK2/TK1	9
BP	GO:0071402	cellular response to lipoprotein particle stimulus	9/2112	34/18670	0.01128	0.05506	0.03978	MYD88/ABCG1/ITGB2/CD36/NPC1/CD9/SYK/CD81/TLR6	9
BP	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	63/2112	419/18670	0.01131	0.05513	0.03984	PSMB9/UCHL1/PSMB8/CLU/PSMB10/PTTG1/SKP1/AREL1/UBE2C/CBFA2T3/MAD2L1/PLK1/PSME1/UBE2B/CHFR/IFI27/SPOP/CDK1/ERLIN1/TBX21/BUB1B/PPP2CB/EDEM1/PCNP/TNFAIP1/PLK2/UBE2D1/FBXL2/ARNTL/VCP/CCNB1/HSP90AB1/ERLIN2/FBXO5/HFE/CRBN/WWTR1/CUL2/TRIM38/RNF19B/DDIT3/AURKB/UBE2J1/TRIM2/CDC20/CUL4B/CEBPA/FBXL7/DVL1/BAG5/EDEM2/KCTD5/CCNF/WAC/PBK/USP7/CAMLG/AURKA/RNF14/TBL1X/UBE2G2/PML/KCTD2	63
BP	GO:0055002	striated muscle cell development	30/2112	173/18670	0.01137	0.05534	0.03998	SGCB/BMP4/UCHL1/IGF1/MYH10/TMOD1/SKI/PPP3CA/SIX1/DYSF/HDAC4/COMP/SHOX2/CDK1/SORBS2/PDLIM5/AFG3L2/SGCD/LMOD1/CCNB1/HEY2/SLC8A1/PAK1/KRT19/AKAP13/MYH11/LMNA/WDR1/CFLAR/ALPK3	30
BP	GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	30/2112	173/18670	0.01137	0.05534	0.03998	SLAMF1/RASGRP1/CCL19/TPD52L1/SEMA3A/CCR7/MAP3K11/NOD2/RIPK2/SPHK1/MAP4K1/CCL21/CD27/CD40LG/ARL6IP5/FZD4/FZD7/MFHAS1/MAP3K2/LEP/PAK1/SYK/IL1RN/LYN/NOD1/HIPK2/NCF1/PRMT1/TLR6/IL1B	30
BP	GO:2000027	regulation of animal organ morphogenesis	41/2112	253/18670	0.01139	0.05543	0.04005	PSMB9/SFRP1/TNFAIP3/BMP4/PSMB8/TNFRSF11B/STAT1/PSMB10/SOX9/PIM1/FOXC1/FGF7/AR/SULF1/SIX1/BMPR1A/SIX2/PSME1/ETV5/NFIB/HGF/MAGI2/PTN/RYK/PLEKHA4/FZD4/FZD7/NOTCH1/TFAP2A/DACT1/ACVR1/GPC4/FZD6/DIO3/DVL1/CFLAR/HOXA11/FZD2/PFN1/LIMS2/AHI1	41
BP	GO:0098754	detoxification	24/2112	131/18670	0.01157	0.05614	0.04056	S100A9/GCH1/NQO1/LTC4S/GSTM3/HBB/CD36/FBLN5/ESD/SOD1/GPX3/IPCEF1/GPX4/HBD/RGN/PRDX6/PTGS1/ADH5/HP/SESN1/GSTO1/CAT/GSTM2/MT1X	24
BP	GO:0010832	negative regulation of myotube differentiation	6/2112	18/18670	0.0116	0.05614	0.04056	HDAC4/CXCL10/CEACAM5/BHLHE41/NOTCH1/CFLAR	6
BP	GO:0045780	positive regulation of bone resorption	6/2112	18/18670	0.0116	0.05614	0.04056	LTBP3/ADAM8/TFRC/EGFR/CA2/SYK	6
BP	GO:0046852	positive regulation of bone remodeling	6/2112	18/18670	0.0116	0.05614	0.04056	LTBP3/ADAM8/TFRC/EGFR/CA2/SYK	6
BP	GO:0070633	transepithelial transport	6/2112	18/18670	0.0116	0.05614	0.04056	AHCYL1/SLC12A2/P2RY6/EDNRB/SLC23A2/P2RY4	6
BP	GO:0090026	positive regulation of monocyte chemotaxis	6/2112	18/18670	0.0116	0.05614	0.04056	CCL5/CCR2/CXCL10/CCR1/FPR2/PLA2G7	6
BP	GO:0001890	placenta development	27/2112	152/18670	0.01161	0.05615	0.04057	CDKN1C/ADAM19/HTRA1/GATA2/EGFR/ADA/E2F8/DCN/BPTF/SPINT2/PTN/SOD1/CTSB/LEF1/LEP/ZFP36L1/ARNT/HEY2/HSP90AB1/FOSL1/KRT19/LDOC1/ANG/CEBPA/HEY1/PKD2/CCNF	27
BP	GO:1901214	regulation of neuron death	49/2112	313/18670	0.01162	0.05615	0.04057	CCL5/NDNF/CRLF1/GDF5/CORO1A/CLU/HLA-F/NQO1/TNFRSF1B/NTRK2/CD200/ANGPT1/AXL/SIGMAR1/ITGB2/OXR1/MAP3K11/SIX1/ADAM8/JAK2/HDAC4/ITSN1/LANCL1/CX3CR1/EPHB1/SOD1/ZPR1/IFNG/KMO/PIK3CA/MECP2/TFAP2A/HSP90AB1/PARP1/IKBKG/STXBP1/TGFB3/PINK1/BACE1/DDIT3/FOXO3/TRIM2/HIPK2/TP53BP2/NAE1/TP53/CCL2/TLR6/CHL1	49
BP	GO:0030048	actin filament-based movement	25/2112	138/18670	0.01162	0.05615	0.04057	MYH10/TMOD1/SRI/CACNA2D1/ANK2/EMP2/WASL/PDPN/KCNJ5/WAS/PLN/PARVA/SGCD/KCNJ2/SCN1B/KCNJ8/DSC2/ATP1A2/FNBP1L/MYO1C/GJC1/WASF2/MYL6B/SNTA1/GPD1L	25
BP	GO:0071901	negative regulation of protein serine/threonine kinase activity	26/2112	145/18670	0.01164	0.05616	0.04058	CDKN2C/SFRP1/TNFAIP3/BMP4/UCHL1/LRP6/CDKN1C/PPP2CA/DUSP5/RASIP1/PLK1/PTPN6/LRP5/HEXIM1/ADIPOQ/MBIP/HSPB1/PTPN22/IPO7/DUSP6/DUSP2/RB1/LYN/CEBPA/SH2B3/IL1B	26
BP	GO:0032467	positive regulation of cytokinesis	10/2112	40/18670	0.01177	0.05672	0.04098	CDC14B/CDC25B/KIF3B/CSPP1/RACGAP1/ECT2/SSTR5/AURKB/KIF20B/KIF23	10
BP	GO:0071470	cellular response to osmotic stress	10/2112	40/18670	0.01177	0.05672	0.04098	RELB/DYSF/AKR1B1/MICU1/ZFP36L1/MBIP/SLC25A23/LRRC8D/PKD2/MYLK	10
BP	GO:0050919	negative chemotaxis	11/2112	46/18670	0.01189	0.05722	0.04135	SEMA4A/SEMA4D/SEMA3A/UNC5C/RYK/SEMA3F/EFNA5/SEMA4F/SEMA3E/SEMA6B/ITGAV	11
BP	GO:1904036	negative regulation of epithelial cell apoptotic process	11/2112	46/18670	0.01189	0.05722	0.04135	NDNF/TNFAIP3/ANGPT1/ICAM1/TNIP2/SCG2/GATA2/TCF7L2/ANGPTL4/KDR/CFLAR	11
BP	GO:0031345	negative regulation of cell projection organization	32/2112	188/18670	0.01196	0.05751	0.04156	SEMA4A/ARPIN/SEMA4D/SEMA3A/PPP3CA/SPOCK1/LPAR1/ZNF365/PFN2/GAK/MAP4/TRAK2/PMP22/FGF13/CCL21/NLGN1/RYK/PTPRS/SEMA3F/PLK2/GDI1/KANK1/MYLIP/DPYSL3/GFI1/ARHGAP4/CD38/BCL11A/SEMA4F/SEMA3E/BAG5/SEMA6B	32
BP	GO:0014812	muscle cell migration	20/2112	104/18670	0.012	0.05766	0.04166	CCL5/IGFBP5/IGF1/PLEKHO1/LPAR1/ITGB1BP1/SIX1/BMPR1A/PDGFD/HDAC4/THBS4/PLAT/NOX4/PARVA/NET1/PAK1/ADIPOQ/P2RY6/FGF9/PRKG1	20
BP	GO:0051057	positive regulation of small GTPase mediated signal transduction	15/2112	71/18670	0.01201	0.05766	0.04166	KITLG/IGF1/RASGRP1/CDON/LPAR1/AUTS2/MAPRE2/JAK2/GPR18/VAV1/GPR65/NOTCH1/AKAP13/LYN/GPR4	15
BP	GO:0031623	receptor internalization	21/2112	111/18670	0.01227	0.05886	0.04253	ANGPT1/TBC1D5/ITGB2/USP46/ACKR3/CD36/HTR2B/DNM1/TFRC/CXCL8/SELE/PLCG2/MAGI2/LRPAP1/CD9/SYK/CD81/ATXN2/MTMR2/LILRB1/AHI1	21
BP	GO:1903362	regulation of cellular protein catabolic process	40/2112	247/18670	0.01246	0.0597	0.04314	LAMP3/NELL1/TNFAIP3/CLU/NFE2L1/CBFA2T3/CTSC/PLK1/PSME1/GABARAPL2/CHFR/BAG2/RHBDF1/EDEM1/PLK2/VCP/MYLIP/RGN/HSP90AB1/DACT1/HFE/PINK1/RNF19B/UBE2J1/CEBPA/HIPK2/DVL1/CD81/BAG5/EDEM2/ALAD/WAC/PBK/ATRAID/USP7/CAMLG/AURKA/RNF14/UBE2G2/PML	40
BP	GO:0009914	hormone transport	50/2112	322/18670	0.01262	0.06037	0.04362	CCL5/SFRP1/SRI/INHBA/OXCT1/PPP3CA/TCIRG1/JAK2/ITSN1/EGFR/SLC16A2/KLF7/TM7SF3/TAC1/PASK/MPC2/NMB/CYB5R4/TCF7L2/PER2/LRP5/FZD4/CPE/EFNA5/PTPN11/RBP4/ARNTL/SLC25A4/LEP/SSTR5/AGTR1/IFNG/ADIPOQ/STX4/HFE/BTK/IL6/CD38/SYBU/ENSA/IL1RN/SLC25A5/LYN/REN/SLCO1C1/HADH/RAB11FIP2/IL1B/RAB11FIP1/GPR27	50
BP	GO:0018209	peptidyl-serine modification	50/2112	322/18670	0.01262	0.06037	0.04362	NDNF/PRKCH/SPOCK2/PRKCQ/NTRK2/VRK2/PRKCB/ANGPT1/HCLS1/PFN2/VRK1/PLK1/PRKD2/RIPK2/EGFR/STK32B/DCN/BGN/MAP4K1/CDK1/BAK1/HGF/MAPK13/RPS6KA4/PLK2/CDC7/IFNG/CCNB1/PIK3CA/PPM1F/HSP90AB1/PAK1/SYK/PARP1/PINK1/AKT3/MAPKAPK2/MARK1/IL6/TTK/PRKG1/NLK/AURKB/PRKD1/HIPK2/AURKA/IFNA1/DCLK1/PRKG2/GPD1L	50
BP	GO:0042133	neurotransmitter metabolic process	27/2112	153/18670	0.01262	0.06037	0.04362	CLU/GCH1/NQO1/ALDH7A1/TLR2/HBB/ITGB2/ICAM1/JAK2/CD36/DDAH2/SLC1A3/CLEC7A/CX3CR1/MAOA/NAALAD2/SMAD3/IFNG/RGN/HSP90AB1/MAOB/GLA/PKD2/TLR6/IL1B/PTX3/ALDH5A1	27
BP	GO:0003158	endothelium development	24/2112	132/18670	0.01267	0.06053	0.04373	BMP4/CXCR4/GSTM3/ICAM1/ARHGEF26/PRKD2/CXCL10/PDPN/TMEM100/PPP1R16B/PTN/PTPRS/TNMD/NOTCH1/PECAM1/HEY2/ACVR1/ITGAX/APOLD1/HEY1/KDR/S1PR1/IL1B/CDH5	24
BP	GO:0051384	response to glucocorticoid	26/2112	146/18670	0.01268	0.06053	0.04373	CDO1/PAM/ICAM1/ANXA3/EGFR/PCK1/PAPPA/FOXO1/ZFP36L1/SSTR5/FLT3/ALPL/ADIPOQ/CCND1/FOSL1/IL6/AKAP13/MAOB/TYMS/FOXO3/IL1RN/ABCA3/IGFBP2/CFLAR/ZFP36L2/ALAD	26
BP	GO:0003016	respiratory system process	8/2112	29/18670	0.01283	0.06093	0.04402	FTO/NDN/PBX3/NLGN1/ATP1A2/MECP2/ADH5/HOXA5	8
BP	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling	8/2112	29/18670	0.01283	0.06093	0.04402	ANK2/HDAC4/PLN/ATP1B1/ATP1A2/SLC8A1/GSTO1/GSTM2	8
BP	GO:0033032	regulation of myeloid cell apoptotic process	8/2112	29/18670	0.01283	0.06093	0.04402	CCL5/KITLG/CCR5/NOD2/IRF7/PIK3CD/ADIPOQ/THRA	8
BP	GO:0050855	regulation of B cell receptor signaling pathway	8/2112	29/18670	0.01283	0.06093	0.04402	LPXN/PRKCH/PRKCB/CD19/PAX5/PTPN22/LYN/CD81	8
BP	GO:0072538	T-helper 17 type immune response	8/2112	29/18670	0.01283	0.06093	0.04402	IL27RA/PRKCQ/BATF/IRF4/MALT1/TBX21/IL6/NLRP3	8
BP	GO:0072606	interleukin-8 secretion	8/2112	29/18670	0.01283	0.06093	0.04402	CD2/FCN1/TLR2/LGALS9/LEP/PTPN22/ANXA4/TLR6	8
BP	GO:1900027	regulation of ruffle assembly	8/2112	29/18670	0.01283	0.06093	0.04402	PFN2/ICAM1/COBL/SH3YL1/NLGN1/KANK1/RHOG/PFN1	8
BP	GO:0045927	positive regulation of growth	43/2112	270/18670	0.01303	0.06185	0.04469	SFRP1/S100A9/IGF1/RFTN1/CXCR4/SEMA4D/PIM1/SASH3/ZFPM2/BMPR1A/YAP1/RPS6KA1/EGFR/HBEGF/FGF2/TGFBR3/SPHK1/TRPV2/GHR/ERBB2/CDK1/ACACB/ZPR1/LEF1/HYAL1/EFNA5/NOTCH1/GDI1/LEP/CCNB1/HEY2/PPM1F/SYT17/PAK1/FGF9/NIPBL/MAP1B/LGI1/CD38/MEGF8/CYBA/ADAM10/DIO3	43
BP	GO:0048738	cardiac muscle tissue development	38/2112	233/18670	0.01308	0.06204	0.04482	SGCB/BMP4/IGF1/MYH10/PIM1/FOXC1/MEIS1/CBY1/ZFPM2/BMPR1A/YAP1/FGF2/TGFBR3/CDK1/SIK1/KCNK2/SORBS2/PLN/PDLIM5/NOX4/SGCD/FZD7/RBP4/NOTCH1/CCNB1/HEY2/SLC8A1/PAK1/ACVR1/FGF9/AKAP13/JARID2/MYH11/LMNA/GJC1/TENM4/S1PR1/ALPK3	38
BP	GO:0001836	release of cytochrome c from mitochondria	13/2112	59/18670	0.01322	0.06257	0.04521	IGF1/CLU/BID/TNFSF10/BAK1/HGF/PMAIP1/FAM162A/HIGD1A/PINK1/LMNA/TP53/MOAP1	13
BP	GO:0061077	chaperone-mediated protein folding	13/2112	59/18670	0.01322	0.06257	0.04521	CLU/CD74/GAK/HSPA6/CRTAP/FKBP5/DNAJC7/PEX19/HSPB1/HSPB6/HSPA1L/DNAJB4/ST13	13
BP	GO:0007009	plasma membrane organization	20/2112	105/18670	0.0133	0.06291	0.04545	PTPRC/BIN2/CLU/MICALL1/MYH10/CXCR4/ANK2/AR/DYSF/WASL/FA2H/SOD1/FNBP1L/FAT4/PLSCR1/MPP5/SH3TC2/UGCG/SPTBN1/GSN	20
BP	GO:0006635	fatty acid beta-oxidation	15/2112	72/18670	0.01363	0.06442	0.04655	ACADVL/ACOX2/ECHDC2/ACAT1/ETFB/ACACB/LEP/BDH2/ECI2/ADIPOQ/ECI1/ACADL/HADH/ECHS1/HADHA	15
BP	GO:0008202	steroid metabolic process	51/2112	331/18670	0.01365	0.06447	0.04658	PLEKHA1/LBR/APOL1/AKR1C3/ACADVL/ABCG1/NFE2L1/ACOX2/STS/SGPL1/PMVK/AKR1B1/CYB5R3/AKR1C1/NPC1/FAXDC2/ERLIN1/SP1/ACAT1/SCARF1/SOD1/ACACB/PBX1/CYB5R1/NFKB1/SC5D/HSD17B12/LEP/AGTR1/IFNG/MECP2/NFYA/ERLIN2/GFI1/CETP/HDLBP/DHRS9/UGT2B17/OSBPL1A/MBTPS2/SLC27A5/CYP46A1/CEBPA/ACADL/OSBPL9/DKK3/CAT/LIPC/IL1B/EPHX2/SOAT2	51
BP	GO:0038066	p38MAPK cascade	12/2112	53/18670	0.01368	0.06451	0.04661	LGALS9/SPHK1/HGF/MFHAS1/LEP/ZFP36L1/PHLPP1/MAPKAPK2/PTPN22/NCF1/PRMT1/IL1B	12
BP	GO:0098801	regulation of renal system process	9/2112	35/18670	0.0137	0.06451	0.04661	EMP2/TAC1/SNX5/CORO2B/AGTR1/OR51E2/ADIPOQ/EDNRB/CYBA	9
BP	GO:0110111	negative regulation of animal organ morphogenesis	9/2112	35/18670	0.0137	0.06451	0.04661	BMP4/TNFRSF11B/STAT1/FOXC1/SULF1/NFIB/NOTCH1/DIO3/LIMS2	9
BP	GO:1904031	positive regulation of cyclin-dependent protein kinase activity	9/2112	35/18670	0.0137	0.06451	0.04661	CCND2/EGFR/CCNT1/CKS2/CCNB1/HSP90AB1/CCND1/CKS1B/PKD2	9
BP	GO:0090263	positive regulation of canonical Wnt signaling pathway	26/2112	147/18670	0.01379	0.0649	0.04689	PSMB9/SFRP1/PSMB8/GPC5/ASPM/PSMB10/WLS/ZBED2/YAP1/PSME1/EGFR/UBE2B/RECK/PLEKHA4/NFKB1/SMAD3/DAAM2/ARNTL/VCP/KANK1/DACT1/FGF9/RNF146/NLE1/FRAT1/TBL1X	26
BP	GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	23/2112	126/18670	0.01381	0.06491	0.0469	SFRP1/SKI/HTRA1/CILP/ADAMTSL2/TWSG1/TGFBR3/MAGI2/GLG1/CHST11/PMEPA1/SMAD3/LDLRAD4/NOTCH1/NBL1/TOB1/CHRDL1/ACVR1/TGFB3/FST/HIPK2/FSTL3/TP53	23
BP	GO:0001837	epithelial to mesenchymal transition	25/2112	140/18670	0.01384	0.06498	0.04695	SFRP1/EPHA3/BMP4/LRP6/DLG5/SOX9/FOXC1/PPP2CA/PDPN/DAG1/TGFBR3/TMEM100/HGF/EZH2/LEF1/SMAD3/LDLRAD4/NOTCH1/HEY2/ACVR1/TGFB3/WWTR1/IL6/HEY1/IL1B	25
BP	GO:0046330	positive regulation of JNK cascade	25/2112	140/18670	0.01384	0.06498	0.04695	SLAMF1/RASGRP1/CCL19/TPD52L1/SEMA3A/CCR7/MAP3K11/NOD2/RIPK2/MAP4K1/CCL21/CD27/CD40LG/FZD4/FZD7/MFHAS1/MAP3K2/PAK1/SYK/IL1RN/NOD1/HIPK2/NCF1/TLR6/IL1B	25
BP	GO:0070849	response to epidermal growth factor	11/2112	47/18670	0.01398	0.06551	0.04733	SOX9/FOXC1/EGFR/TPR/ERBB2/SKAP1/ZPR1/PTPN11/ZFP36L1/CFLAR/ZFP36L2	11
BP	GO:0120163	negative regulation of cold-induced thermogenesis	11/2112	47/18670	0.01398	0.06551	0.04733	HOXC10/IL15/NOVA1/NOTCH1/ARNTL/ADIPOQ/DDIT3/NR1H3/RB1/ABHD6/NPR3	11
BP	GO:0043403	skeletal muscle tissue regeneration	10/2112	41/18670	0.01403	0.06551	0.04733	IGF1/PPP3CA/SGCA/DYSF/DAG1/EZH2/FZD7/CD9/CD81/CFLAR	10
BP	GO:0044091	membrane biogenesis	10/2112	41/18670	0.01403	0.06551	0.04733	RFTN1/EMP2/PTPRD/MAGI2/NLGN1/CDH2/SERINC1/CLIP3/UGCG/SPTBN1	10
BP	GO:0050798	activated T cell proliferation	10/2112	41/18670	0.01403	0.06551	0.04733	IGF1/LGALS9/BTN2A2/PDCD1LG2/BTN3A1/ICOSLG/IL18/IGFBP2/LRRC32/IL2RA	10
BP	GO:0097178	ruffle assembly	10/2112	41/18670	0.01403	0.06551	0.04733	PFN2/ICAM1/ARHGEF26/COBL/SH3YL1/NLGN1/KANK1/RHOG/SNX10/PFN1	10
BP	GO:0150077	regulation of neuroinflammatory response	10/2112	41/18670	0.01403	0.06551	0.04733	PTPRC/IGF1/TNFRSF1B/CST7/CD200/CTSC/SPHK1/IL6/IL18/IL1B	10
BP	GO:0002092	positive regulation of receptor internalization	7/2112	24/18670	0.01429	0.06649	0.04804	ANGPT1/TBC1D5/SELE/PLCG2/MAGI2/SYK/AHI1	7
BP	GO:0042832	defense response to protozoan	7/2112	24/18670	0.01429	0.06649	0.04804	GBP2/BATF/IRF8/IRF4/IL4R/CD40/CLEC7A	7
BP	GO:0044346	fibroblast apoptotic process	7/2112	24/18670	0.01429	0.06649	0.04804	SFRP1/BID/STK17B/BAK1/TP63/PIK3CA/TP53	7
BP	GO:0071677	positive regulation of mononuclear cell migration	7/2112	24/18670	0.01429	0.06649	0.04804	CCL5/CCR2/PDGFD/CXCL10/CCR1/FPR2/PLA2G7	7
BP	GO:1903020	positive regulation of glycoprotein metabolic process	7/2112	24/18670	0.01429	0.06649	0.04804	IGF1/CCL19/IL15/CCR7/GOLGA2/CCL21/TCF7L2	7
BP	GO:1901570	fatty acid derivative biosynthetic process	19/2112	99/18670	0.0144	0.06693	0.04836	LTC4S/AKR1C3/CD74/ACSS3/ACAT1/HPGDS/HSD17B12/BDH2/BDH1/SYK/FABP5/PTGS1/ELOVL4/SLC27A5/ELOVL2/ACSL5/IL1B/ALOX5/ELOVL5	19
BP	GO:0040014	regulation of multicellular organism growth	14/2112	66/18670	0.01442	0.067	0.04841	FTO/GDF5/IGF1/NPY1R/SGPL1/PLAC8/GHR/SOCS2/AFG3L2/SOD1/PIK3CA/PRL/NIPBL/DIO3	14
BP	GO:0048640	negative regulation of developmental growth	21/2112	113/18670	0.01491	0.06921	0.05	SFRP1/BMP4/SEMA4A/SEMA4D/SEMA3A/MEIS1/PLAC8/FGF13/KCNK2/SOCS2/RYK/PTPRS/SEMA3F/RBP4/PAK1/ARHGAP4/BCL11A/SEMA4F/JARID2/SEMA3E/SEMA6B	21
BP	GO:0071383	cellular response to steroid hormone stimulus	40/2112	250/18670	0.01505	0.06981	0.05044	SFRP1/BMP4/RBFOX2/LMO3/AKR1C3/AR/KANK2/ICAM1/JAK2/YAP1/EGFR/NPC1/TAF7/UFSP2/PGRMC2/PCK1/TP63/PMEPA1/LEF1/FOXO1/ARNTL/ZFP36L1/SSTR5/ATP1A2/OR51E2/FLT3/PAK1/PARP1/CALCOCO1/AKAP13/NR1H3/FOXO3/RB1/TFPI/RWDD1/CFLAR/ZFP36L2/NRIP1/RNF14/THRA	40
BP	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	17/2112	86/18670	0.01507	0.06986	0.05047	COPZ2/TAPBP/ATP9A/KIF11/KIF15/KIF3B/RAB33B/KIF2C/KIF4A/KDELR3/RACGAP1/STX18/KDELR2/NBAS/ERGIC2/USE1/KIF23	17
BP	GO:0032355	response to estradiol	24/2112	134/18670	0.01511	0.06995	0.05054	SFRP1/PENK/NQO1/PAM/CRYAB/EGFR/CCNA2/EZH2/SOCS2/PTN/BCL2L2/GPX4/LEP/CSN1S1/PTGFR/CCND1/STXBP1/MAP1B/CD38/TFPI/IGFBP2/CFLAR/CAT/NRIP1	24
BP	GO:0046683	response to organophosphorus	24/2112	134/18670	0.01511	0.06995	0.05054	IGFBP5/CDO1/PENK/STAT1/LPAR1/AQP9/NDUFS4/AKR1C1/PCK1/NOX4/RFC3/SOD1/ZFP36L1/SLC8A1/ADIPOQ/P2RY6/FOSL1/TYMS/RYR3/PANX1/PKD2/REN/IL1B/P2RY4	24
BP	GO:0030522	intracellular receptor signaling pathway	44/2112	280/18670	0.01514	0.07001	0.05059	SFRP1/TNFAIP3/BIRC3/RBFOX2/LMO3/PIM1/AKR1C3/AR/KANK2/NOD2/IRF7/JAK2/IFIH1/YAP1/RIPK2/TRIM24/DHRS3/TSPAN6/TAF7/UFSP2/EZH2/NFKBIA/TP63/PMEPA1/DDX58/ARNTL/LEP/DDX60/ARNT/PAK1/FABP5/PARP1/IKBKG/CALCOCO1/PTPN22/NR1H3/RB1/NOD1/RWDD1/DCBLD2/NRIP1/RNF14/PML/THRA	44
BP	GO:1902110	positive regulation of mitochondrial membrane permeability involved in apoptotic process	13/2112	60/18670	0.01517	0.07007	0.05063	TFDP2/GZMB/BID/EYA2/TMEM14A/BAK1/TP63/PMAIP1/SLC25A5/TP53BP2/TP53/BNIP3L/MOAP1	13
BP	GO:0043409	negative regulation of MAPK cascade	31/2112	184/18670	0.01517	0.07007	0.05063	SFRP1/PTPRC/BMP4/GBP1/UCHL1/CSK/TIMP3/LMO3/PPP2CA/DUSP5/PTPN2/ITGB1BP1/BTN2A2/DAG1/PTPN6/PEBP1/FOXO1/ZMYND11/ADIPOQ/DACT1/MBIP/PINK1/PTPN22/DUSP6/DUSP2/FBLN1/LYN/SH2B3/PBK/NDRG2/IL1B	31
BP	GO:0003188	heart valve formation	5/2112	14/18670	0.01535	0.07022	0.05074	SOX9/DCHS1/NOTCH1/HEY2/HEY1	5
BP	GO:0006268	DNA unwinding involved in DNA replication	5/2112	14/18670	0.01535	0.07022	0.05074	PURA/BLM/MCM2/MCM4/HMGA1	5
BP	GO:0010935	regulation of macrophage cytokine production	5/2112	14/18670	0.01535	0.07022	0.05074	CD74/HLA-G/CD36/TGFB3/LILRB1	5
BP	GO:0043374	CD8-positive, alpha-beta T cell differentiation	5/2112	14/18670	0.01535	0.07022	0.05074	IRF1/RUNX3/SOCS1/GPR18/NCKAP1L	5
BP	GO:0045064	T-helper 2 cell differentiation	5/2112	14/18670	0.01535	0.07022	0.05074	BATF/IL4R/CD86/IL18/NLRP3	5
BP	GO:0045953	negative regulation of natural killer cell mediated cytotoxicity	5/2112	14/18670	0.01535	0.07022	0.05074	HLA-F/HLA-G/LGALS9/HLA-E/LILRB1	5
BP	GO:0070234	positive regulation of T cell apoptotic process	5/2112	14/18670	0.01535	0.07022	0.05074	CCL5/IDO1/LGALS9/ADAM8/TP53	5
BP	GO:0070669	response to interleukin-2	5/2112	14/18670	0.01535	0.07022	0.05074	IL2RG/IL2RB/PTPN2/SYK/IL2RA	5
BP	GO:0098543	detection of other organism	5/2112	14/18670	0.01535	0.07022	0.05074	TLR2/NOD2/CLEC7A/NOD1/TLR6	5
BP	GO:1900121	negative regulation of receptor binding	5/2112	14/18670	0.01535	0.07022	0.05074	PTPRF/LEF1/ADIPOQ/HFE/CRTAC1	5
BP	GO:2001212	regulation of vasculogenesis	5/2112	14/18670	0.01535	0.07022	0.05074	EMP2/TMEM100/HEY2/HEY1/KDR	5
BP	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway	6/2112	19/18670	0.01536	0.07022	0.05074	FGF18/PRKCB/PRKD2/ARNT/FGF9/IL1B	6
BP	GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response	6/2112	19/18670	0.01536	0.07022	0.05074	CD74/HLA-G/CD36/DDX58/DDX1/LILRB1	6
BP	GO:0002312	B cell activation involved in immune response	15/2112	73/18670	0.01541	0.07037	0.05085	PTPRC/IL27RA/GPR183/BATF/DOCK10/CD40/TFRC/ADA/PLCG2/TBX21/CD40LG/CD19/CD180/ERCC1/THOC1	15
BP	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	15/2112	73/18670	0.01541	0.07037	0.05085	CXCL13/CXCL9/S100A9/CCL13/GNLY/CXCL1/CXCL10/CXCL8/CXCL3/CXCL11/KRT6A/CXCL2/CXCL5/CXCL6/SPINK5	15
BP	GO:0009266	response to temperature stimulus	39/2112	243/18670	0.01546	0.07055	0.05098	IGF1/CXCR4/IER5/ACADVL/NFE2L1/CRYAB/NUP93/MICB/PLAC8/HTR2B/CXCL10/TFEC/CREBBP/HSPA6/TRPV2/TPR/BAG2/EPHB1/NFKBIA/NUP160/SOD1/HTR2A/FOXO1/VCP/TMEM135/LXN/HSP90AB1/DNAJC7/MAPKAPK2/UCP2/LYN/HSPA1L/NUP88/BAG5/DNAJB4/NUP50/DNAJC2/THRA/PSIP1	39
BP	GO:0072080	nephron tubule development	18/2112	93/18670	0.01557	0.071	0.0513	BMP4/STAT1/SOX9/GLI3/SIX1/SIX2/YAP1/FGF2/ACAT1/PBX1/DCHS1/NOTCH1/WWTR1/FAT4/PKD2/POU3F3/HOXA11/AHI1	18
BP	GO:0019724	B cell mediated immunity	36/2112	221/18670	0.01566	0.07122	0.05146	TRBC1/XCL1/PTPRC/IL27RA/CLU/TLR8/BATF/CD74/TCIRG1/IL4R/HLA-G/IRF7/CD40/TFRC/HLA-E/PTPN6/CR1/IGHM/IGLL5/CD226/TBX21/IL13RA2/CD27/CD40LG/CD19/IGLC1/IGLV1-44/C7/BTK/IGHG1/INPP5D/CD81/ERCC1/THOC1/CR2/C6	36
BP	GO:0007179	transforming growth factor beta receptor signaling pathway	33/2112	199/18670	0.01567	0.07122	0.05146	GDF5/FMOD/CDKN1C/LTBP3/SKI/PARD3/ARHGEF18/HTRA1/FERMT2/LTBP2/BMPR1A/ADAMTSL2/TWSG1/TGFBR3/CREBBP/GLG1/CHST11/PMEPA1/SMAD3/LDLRAD4/HSP90AB1/ACVR1/PARP1/TGFB3/NLK/FERMT1/HIPK2/DKK3/FUT8/LRRC32/TP53/CDH5/PML	33
BP	GO:0035966	response to topologically incorrect protein	33/2112	199/18670	0.01567	0.07122	0.05146	PIK3R1/CLU/ACADVL/PTPN2/EXTL2/COMP/TM7SF3/THBS4/HSPA6/CXCL8/SEC31A/CREB3L2/BAK1/TSPYL2/HSPA4L/EDEM1/KDELR3/VCP/GFPT1/FKBP14/HSP90AB1/CCND1/HSPB1/SDF2L1/DDIT3/LMNA/MBTPS2/HSPA1L/EDEM2/DNAJB4/HSPB2/TATDN2/CCL2	33
BP	GO:0071772	response to BMP	29/2112	170/18670	0.01568	0.07122	0.05146	SFRP1/GDF5/BMP4/SOX9/SKI/HTRA1/SULF1/BMPR1A/COMP/TWSG1/TGFBR3/TMEM100/SPINT2/NEO1/LEF1/TNMD/UBE2D1/NOTCH1/NBL1/TOB1/CHRDL1/ACVR1/HFE/MEGF8/FST/HIPK2/FSTL3/ZNF8/CDH5	29
BP	GO:0071773	cellular response to BMP stimulus	29/2112	170/18670	0.01568	0.07122	0.05146	SFRP1/GDF5/BMP4/SOX9/SKI/HTRA1/SULF1/BMPR1A/COMP/TWSG1/TGFBR3/TMEM100/SPINT2/NEO1/LEF1/TNMD/UBE2D1/NOTCH1/NBL1/TOB1/CHRDL1/ACVR1/HFE/MEGF8/FST/HIPK2/FSTL3/ZNF8/CDH5	29
BP	GO:2000146	negative regulation of cell motility	53/2112	349/18670	0.0158	0.07129	0.05151	CXCL13/SLAMF8/SFRP1/IGFBP5/IL27RA/LIMCH1/DLG5/ARHGDIB/ARPIN/SEMA3A/MCTP1/CD200/CD74/PFN2/ITGB1BP1/SULF1/BMPR1A/WASL/RECK/ADA/DAG1/DLC1/FGF2/GPR18/DCN/ADORA3/IDH2/CCL21/WAS/SPINT2/MAGI2/CX3CR1/PTN/C5orf30/RRAS/LDLRAD4/NOTCH1/KANK1/NBL1/RGN/MECP2/PTGER4/ADIPOQ/DPYSL3/ARHGAP4/PRKG1/MIIP/FOXO3/AP1AR/FBLN1/ABHD6/CCL2/SCAI	53
BP	GO:0001782	B cell homeostasis	8/2112	30/18670	0.0158	0.07129	0.05151	TNFAIP3/DOCK10/SH2B2/CD74/ADA/BAK1/NCKAP1L/LYN	8
BP	GO:0001844	protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	8/2112	30/18670	0.0158	0.07129	0.05151	TFDP2/GZMB/BID/TP63/PMAIP1/TP53BP2/TP53/MOAP1	8
BP	GO:0046596	regulation of viral entry into host cell	8/2112	30/18670	0.0158	0.07129	0.05151	FCN1/CD74/LGALS9/TRIM21/TRIM38/TRIM26/GSN/PTX3	8
BP	GO:0048873	homeostasis of number of cells within a tissue	8/2112	30/18670	0.0158	0.07129	0.05151	CCR2/CORO1A/SOX9/SASH3/GATA2/PTPN11/NOTCH1/AKT3	8
BP	GO:0070168	negative regulation of biomineral tissue development	8/2112	30/18670	0.0158	0.07129	0.05151	ENPP1/SOX9/LTBP3/SRGN/CCR1/NOTCH1/HEY2/HEY1	8
BP	GO:0090200	positive regulation of release of cytochrome c from mitochondria	8/2112	30/18670	0.0158	0.07129	0.05151	BID/TNFSF10/BAK1/PMAIP1/FAM162A/PINK1/TP53/MOAP1	8
BP	GO:0097421	liver regeneration	8/2112	30/18670	0.0158	0.07129	0.05151	GLI3/EGFR/EZH2/RGN/CCND1/HFE/TYMS/AURKA	8
BP	GO:0030042	actin filament depolymerization	12/2112	54/18670	0.01583	0.07129	0.05151	ADD3/TMOD1/PLEK/DSTN/LMOD1/MICAL1/CFL1/CAPZA1/VILL/WDR1/SPTBN1/GSN	12
BP	GO:0043392	negative regulation of DNA binding	12/2112	54/18670	0.01583	0.07129	0.05151	GZMA/SRI/JAK2/ID3/PER2/NFKBIA/NEK2/LEF1/HEY2/DDIT3/RSF1/HEY1	12
BP	GO:0061005	cell differentiation involved in kidney development	12/2112	54/18670	0.01583	0.07129	0.05151	BMP4/STAT1/GLI3/SIX2/YAP1/MAGI2/NOTCH1/ADIPOQ/WWTR1/FAT4/POU3F3/GPR4	12
BP	GO:0090329	regulation of DNA-dependent DNA replication	12/2112	54/18670	0.01583	0.07129	0.05151	ZNF365/BLM/E2F8/STAG2/RFC3/ATRX/DONSON/TIMELESS/CDC7/TERF1/DBF4/FBXO5	12
BP	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	19/2112	100/18670	0.01595	0.07165	0.05177	PLCE1/LPAR1/GPR18/CX3CR1/HTR2A/HRH1/GPR65/FPR1/AGTR1/P2RY6/EDNRB/FPR2/NPR3/S1PR1/PTH1R/TGM2/GPR4/P2RY4/GPR27	19
BP	GO:0055024	regulation of cardiac muscle tissue development	19/2112	100/18670	0.01595	0.07165	0.05177	BMP4/IGF1/PIM1/MEIS1/ZFPM2/BMPR1A/YAP1/FGF2/TGFBR3/CDK1/KCNK2/FZD7/RBP4/NOTCH1/CCNB1/HEY2/PAK1/FGF9/JARID2	19
BP	GO:0090174	organelle membrane fusion	19/2112	100/18670	0.01595	0.07165	0.05177	TAP1/TAPBP/CORO1A/TAP2/RAB8A/LRMP/DYSF/SPHK1/SAMD9/VCPIP1/STX16/VPS16/RAB20/STX4/STXBP1/CHMP2B/STX6/VTI1B/VAV3	19
BP	GO:0007254	JNK cascade	35/2112	214/18670	0.01604	0.07203	0.05204	SFRP1/SLAMF1/RASGRP1/CCL19/TPD52L1/SEMA3A/CCR7/MAP3K11/NOD2/RIPK2/EGFR/MAP4K1/CCL21/CD27/EPHB1/CD40LG/FZD4/FZD7/MFHAS1/ZMYND11/MAP3K2/PTGER4/PAK1/DACT1/SYK/PHLPP1/IKBKG/PINK1/PTPN22/IL1RN/NOD1/HIPK2/NCF1/TLR6/IL1B	35
BP	GO:1900046	regulation of hemostasis	16/2112	80/18670	0.0162	0.07269	0.05252	PRKCQ/CD36/COMP/PDPN/PROS1/PLEK/VKORC1/PLAT/CD9/SYK/TEC/PRKG1/TFPI/LYN/SH2B3/GP1BA	16
BP	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	11/2112	48/18670	0.01633	0.07321	0.05289	PCDHB3/CDH19/SELL/PCDHB13/PCDHB11/NLGN1/CDH2/DCHS1/PCDHGC3/PCDHB6/CDH5	11
BP	GO:0010675	regulation of cellular carbohydrate metabolic process	25/2112	142/18670	0.01639	0.07321	0.05289	ENPP1/IGF1/NFE2L1/PTPN2/CBFA2T3/HDAC4/PASK/PLEK/SIK1/COX11/ACACB/FAM3C/PMAIP1/FOXO1/HRH1/LEP/PPP1CA/RGN/ADIPOQ/P2RY6/PDK4/SORBS1/SCARB2/PTH1R/TP53	25
BP	GO:0034332	adherens junction organization	25/2112	142/18670	0.01639	0.07321	0.05289	SFRP1/EPHA3/LIMCH1/CSK/DLG5/CDH19/MAPRE2/ITGB1BP1/FERMT2/DLC1/CDH2/CADM1/EFNA5/SMAD3/CORO2B/MYOC/PPM1F/TRIP6/SORBS1/CTTN/RHOD/ANG/KDR/COL16A1/CDH5	25
BP	GO:1900542	regulation of purine nucleotide metabolic process	25/2112	142/18670	0.01639	0.07321	0.05289	PID1/IGF1/ZBTB20/SLC2A6/CBFA2T3/COX7A1/NUP93/HDAC4/TPR/CDK1/NUP160/HTR2A/VCP/IFNG/ARNT/CCNB1/PDK4/PARP1/SLC25A23/PINK1/GUCA1A/NUP88/NUP50/TP53/COX7A2	25
BP	GO:0045446	endothelial cell differentiation	21/2112	114/18670	0.01639	0.07321	0.05289	BMP4/CXCR4/GSTM3/ICAM1/ARHGEF26/PDPN/TMEM100/PPP1R16B/PTN/PTPRS/TNMD/NOTCH1/PECAM1/HEY2/ACVR1/APOLD1/HEY1/KDR/S1PR1/IL1B/CDH5	21
BP	GO:0060349	bone morphogenesis	21/2112	114/18670	0.01639	0.07321	0.05289	BMP4/LRP6/SCARA3/FGF18/SOX9/GLI3/LTBP3/FOXC1/SKI/COCH/COMP/SHOX2/DHRS3/COL14A1/GLG1/LRP5/TFAP2A/ALPL/TGFB3/MEGF8/HOXA11	21
BP	GO:0007498	mesoderm development	24/2112	135/18670	0.01647	0.07336	0.053	BMP4/SECTM1/FOXC1/INHBA/PPP2CA/ZFPM2/EYA2/BMPR1A/WLS/JAK2/SIX2/YAP1/TWSG1/TP63/LEF1/SMAD3/ZFP36L1/ACVR1/MEST/BTK/EXT2/HCK/IKZF1/HOXA11	24
BP	GO:0002755	MyD88-dependent toll-like receptor signaling pathway	9/2112	36/18670	0.01648	0.07336	0.053	IRF1/TLR8/MYD88/TLR2/IRF7/CD36/TLR5/BTK/TLR6	9
BP	GO:0042554	superoxide anion generation	9/2112	36/18670	0.01648	0.07336	0.053	ITGB2/EGFR/CLEC7A/NOX4/SOD1/SYK/FPR2/CYBA/NCF1	9
BP	GO:0060428	lung epithelium development	9/2112	36/18670	0.01648	0.07336	0.053	BMP4/SOX9/FGF7/ADAMTSL2/YAP1/NFIB/RCN3/HOXA5/THRA	9
BP	GO:0048675	axon extension	22/2112	121/18670	0.01648	0.07336	0.053	SEMA4A/NDN/SEMA4D/SEMA3A/AUTS2/TRPV2/RYK/PTPRS/SEMA3F/GDI1/HSP90AB1/PAK1/CTTN/MAP1B/ARHGAP4/MEGF8/DPYSL2/SEMA4F/SEMA3E/DVL1/SEMA6B/DCLK1	22
BP	GO:0030517	negative regulation of axon extension	10/2112	42/18670	0.01659	0.07381	0.05333	SEMA4A/SEMA4D/SEMA3A/RYK/PTPRS/SEMA3F/ARHGAP4/SEMA4F/SEMA3E/SEMA6B	10
BP	GO:0046879	hormone secretion	48/2112	312/18670	0.01674	0.07442	0.05377	CCL5/SFRP1/SRI/INHBA/OXCT1/PPP3CA/TCIRG1/JAK2/ITSN1/EGFR/KLF7/TM7SF3/TAC1/PASK/MPC2/NMB/CYB5R4/TCF7L2/PER2/LRP5/FZD4/CPE/EFNA5/PTPN11/RBP4/ARNTL/SLC25A4/LEP/SSTR5/AGTR1/IFNG/ADIPOQ/STX4/HFE/BTK/IL6/CD38/SYBU/ENSA/IL1RN/SLC25A5/LYN/REN/HADH/RAB11FIP2/IL1B/RAB11FIP1/GPR27	48
BP	GO:0016569	covalent chromatin modification	69/2112	474/18670	0.01676	0.07443	0.05378	NAP1L2/EYA4/ING3/SKI/PRKCB/SKP1/IRF4/AUTS2/SIRT7/CHD1/EYA2/VRK1/BAZ1A/JAK2/HDAC4/PRKD2/GATA2/UBE2B/USP3/CREBBP/KMT2A/TAF7/CDK1/CCNA2/EZH2/PER2/RPS6KA4/LEF1/DNMT1/ATRX/BRD4/PAX5/CCNB1/EID1/MECP2/MTF2/MSL3/PPM1F/MPHOSPH8/MBIP/RLF/GFI1/KAT6B/SPI1/NIPBL/PAF1/PINK1/SUZ12/PHF10/SMYD2/HELLS/JARID2/LMNA/AURKB/RSF1/KDM7A/MORF4L1/PRKD1/CUL4B/PRMT1/SETMAR/EZH1/WAC/TP53/USP7/AURKA/KDM2A/TBL1X/IL1B	69
BP	GO:0030900	forebrain development	57/2112	381/18670	0.01687	0.07486	0.05409	BMP4/BCL11B/LRP6/TACC3/GNG12/ASPM/BCL2A1/MYH10/CXCR4/GLI3/NTRK2/TSKU/SEMA3A/SKI/INHBA/CDON/LPAR1/AXL/BMPR1A/ANXA3/TWSG1/GATA2/EGFR/DLC1/NFIB/FGF13/TACC1/EZH2/SOX2/PTN/CDH2/PITX1/MCPH1/RYK/PTPRS/TCTN1/LEF1/DIXDC1/ATRX/NOTCH1/FEZ1/TACC2/PAX5/SLC8A1/APAF1/PRKG1/FAT4/EMX2/CRTAC1/POU3F3/EZH1/RFX4/FEZF2/GDPD5/MBOAT7/DCLK1/STIL	57
BP	GO:0008037	cell recognition	35/2112	215/18670	0.01714	0.07602	0.05493	TRBC1/EPHA3/PRF1/CXCR4/NDN/FCN1/CCL19/SEMA3A/CCR7/CD5/CD36/CRTAM/CLEC7A/IGHM/IGLL5/CCL21/CD226/EPHB1/CADM1/VCAN/CD6/DOCK2/CD9/COLEC12/IGLC1/PECAM1/MEGF8/IGHG1/CRTAC1/HSPA1L/OVGP1/CD81/PCDHB6/FEZF2/UBAP2L	35
BP	GO:0007219	Notch signaling pathway	32/2112	193/18670	0.01716	0.07606	0.05496	SUSD5/GALNT11/STAT1/SOX9/FOXC1/ITGB1BP1/TIMP4/NOD2/GATA2/EGFR/CREBBP/TMEM100/DLGAP5/SORBS2/PLN/NFKBIA/TP63/CFD/PBX1/NOTCH1/IL6ST/HEY2/TSPAN14/KRT19/FAT4/ANXA4/ADAM10/CEBPA/HEY1/NLE1/IL2RA/GDPD5	32
BP	GO:0051289	protein homotetramerization	18/2112	94/18670	0.01728	0.07655	0.05531	CD247/CBY1/PCBD1/GOLGA2/TP63/ACACB/KCNJ2/GPX3/VASP/MAT1A/RYR3/ACADL/PKD2/CAT/TK1/TP53/ALDH5A1/ST13	18
BP	GO:1903902	positive regulation of viral life cycle	13/2112	61/18670	0.01734	0.07675	0.05546	CCL5/NUCKS1/CD74/LGALS9/PC/SRPK1/TOP2A/TRIM21/NOTCH1/ADAR/TRIM38/CHMP2B/KPNA2	13
BP	GO:1904018	positive regulation of vasculature development	37/2112	230/18670	0.01737	0.07682	0.0555	FGF18/CXCR4/PRKCB/ITGB2/PDGFD/CD40/PRKD2/ANXA3/GATA2/FGF2/SPHK1/CXCL8/TMEM100/HGF/SP1/CX3CR1/PPP1R16B/RRAS/HYAL1/ANGPTL4/PLK2/NOTCH1/AGTR1/APLNR/ITGAX/HSPB1/AKT3/HSPB6/VEGFB/PRKD1/HIPK2/KDR/CFLAR/IL1B/CDH5/C6/CTSH	37
BP	GO:0031570	DNA integrity checkpoint	27/2112	157/18670	0.0174	0.07692	0.05558	TFDP2/DTL/PLK1/CDC14B/CDC45/BLM/E2F8/CDK1/TOP2A/PTPN11/PLK2/DONSON/TIMELESS/CCNB1/CCND1/CEP63/SYF2/NAE1/THOC1/PRMT1/SETMAR/PCBP4/WAC/TP53/AURKA/TOPBP1/PML	27
BP	GO:0003002	regionalization	53/2112	351/18670	0.0175	0.07729	0.05584	SFRP1/BMP4/LRP6/HOXC10/HOXA10/ZBTB16/PBX3/GLI3/FOXC1/SEMA3A/SKI/CDON/AR/HOXC6/SIX1/BMPR1A/WLS/SIX2/COBL/MEOX1/BPTF/SMARCD3/HOXC4/LRP5/TP63/PBX1/TCTN1/LEF1/SEMA3F/SMAD3/BHLHE41/NOTCH1/NBL1/MTF2/HEY2/HOXA4/ACVR1/HOXD10/TULP3/MEGF8/DDIT3/SCMH1/EMX2/HIPK2/HEY1/NLE1/HOXA11/TP53/RFX4/FEZF2/AURKA/HOXA5/AHI1	53
BP	GO:0070507	regulation of microtubule cytoskeleton organization	31/2112	186/18670	0.01752	0.07732	0.05587	EPHA3/TACC3/MAPRE2/PLK1/TPX2/BORA/CKAP2/KIF11/FGF13/TPR/MAP9/STAG2/TUBB4A/MCPH1/NEK2/EFNA5/DIXDC1/PLK2/MECP2/TERF1/PAK1/CAMSAP2/CEP85/MAP1B/CHMP2B/CLIP3/CCNF/AURKA/CDH5/CHMP1B/STIL	31
BP	GO:0070838	divalent metal ion transport	70/2112	483/18670	0.01763	0.07775	0.05618	CCL5/CXCL9/CCR5/XCL1/LCK/PTPRC/YME1L1/CORO1A/LILRB2/PLCE1/CXCR4/CCL19/SRI/CACNA2D1/ANK2/PPP3CA/CCR7/PRKCB/ICAM1/DYSF/HTR2B/GEM/CXCL10/PTPN6/FGF2/TRPV2/MAGT1/PLCG2/CCL21/SLC39A8/BAK1/CCR1/PLN/AFG3L2/MICU1/KCNJ2/MS4A1/TRPC1/HTR2A/CD19/ATP1B1/IL16/IFNG/RGN/ATP1A2/CXCL11/SLC8A1/FGF14/P2RY6/APLNR/SLC25A23/CNNM2/SLC39A6/DDIT3/RYR3/CYBA/LYN/PANX1/PKD2/GSTO1/MYLK/SLC39A7/GSTM2/ITGAV/CCL2/CASK/TRPM6/PML/LILRB1/ATP2A3	70
BP	GO:0001562	response to protozoan	7/2112	25/18670	0.01796	0.07863	0.05682	GBP2/BATF/IRF8/IRF4/IL4R/CD40/CLEC7A	7
BP	GO:0002053	positive regulation of mesenchymal cell proliferation	7/2112	25/18670	0.01796	0.07863	0.05682	STAT1/SOX9/SIX1/BMPR1A/SHOX2/LRP5/FGF9	7
BP	GO:0002335	mature B cell differentiation	7/2112	25/18670	0.01796	0.07863	0.05682	SLAMF8/GPR183/DOCK10/MALT1/ADA/PLCG2/CD19	7
BP	GO:0048103	somatic stem cell division	7/2112	25/18670	0.01796	0.07863	0.05682	ASPM/SOX5/FGF13/LEF1/FZD7/NOTCH1/ZFP36L2	7
BP	GO:0050927	positive regulation of positive chemotaxis	7/2112	25/18670	0.01796	0.07863	0.05682	SCG2/CXCL8/SMAD3/IL16/VEGFB/KDR/S1PR1	7
BP	GO:0051654	establishment of mitochondrion localization	7/2112	25/18670	0.01796	0.07863	0.05682	UCHL1/TRAK2/FEZ1/MARK1/MAP1B/SYBU/KIF1B	7
BP	GO:0051894	positive regulation of focal adhesion assembly	7/2112	25/18670	0.01796	0.07863	0.05682	SFRP1/ITGB1BP1/SMAD3/MYOC/PPM1F/KDR/COL16A1	7
BP	GO:0060561	apoptotic process involved in morphogenesis	7/2112	25/18670	0.01796	0.07863	0.05682	TNFRSF1B/FOXC1/CRYAB/BAK1/LEF1/NOTCH1/SPI1	7
BP	GO:0072012	glomerulus vasculature development	7/2112	25/18670	0.01796	0.07863	0.05682	BMP4/ANGPT1/PDGFD/NOTCH1/PECAM1/CFLAR/GPR4	7
BP	GO:2000482	regulation of interleukin-8 secretion	7/2112	25/18670	0.01796	0.07863	0.05682	CD2/FCN1/TLR2/LGALS9/PTPN22/ANXA4/TLR6	7
BP	GO:1904375	regulation of protein localization to cell periphery	21/2112	115/18670	0.01798	0.07866	0.05683	PID1/PIK3R1/EPHA3/GBP1/EPB41L2/PRKCH/CSK/AR/PLK1/EGFR/DAG1/RHOG/IFNG/STX4/GPC4/SORBS1/ADAM10/CLIP3/VTI1B/RAB11FIP2/SPTBN1	21
BP	GO:0031145	anaphase-promoting complex-dependent catabolic process	16/2112	81/18670	0.01813	0.07928	0.05729	PSMB9/PSMB8/PSMB10/PTTG1/UBE2C/MAD2L1/PLK1/PSME1/CDK1/BUB1B/UBE2D1/CCNB1/FBXO5/AURKB/CDC20/AURKA	16
BP	GO:0032874	positive regulation of stress-activated MAPK cascade	29/2112	172/18670	0.0182	0.07952	0.05746	SLAMF1/RASGRP1/CCL19/TPD52L1/SEMA3A/CCR7/MAP3K11/NOD2/RIPK2/SPHK1/MAP4K1/CCL21/CD27/CD40LG/ARL6IP5/FZD4/FZD7/MFHAS1/MAP3K2/LEP/PAK1/SYK/IL1RN/NOD1/HIPK2/NCF1/PRMT1/TLR6/IL1B	29
BP	GO:0042304	regulation of fatty acid biosynthetic process	12/2112	55/18670	0.01822	0.07957	0.05749	ACADVL/CD74/ERLIN1/RGN/ADIPOQ/ERLIN2/FABP5/PDK4/NR1H3/ACADL/IL1B/ELOVL5	12
BP	GO:0016239	positive regulation of macroautophagy	14/2112	68/18670	0.01856	0.08085	0.05842	PIP4K2B/RIPK2/DCN/IKBKG/PINK1/PIP4K2A/SESN1/NOD1/EPM2A/KDR/FYCO1/WAC/BNIP3L/PIM2	14
BP	GO:0035924	cellular response to vascular endothelial growth factor stimulus	14/2112	68/18670	0.01856	0.08085	0.05842	GAS1/FOXC1/ITGB1BP1/PRKD2/SPHK1/DCN/NOTCH1/FLT3/MYO1C/HSPB1/MAPKAPK2/VEGFB/PRKD1/KDR	14
BP	GO:0045806	negative regulation of endocytosis	14/2112	68/18670	0.01856	0.08085	0.05842	EPHA3/CSK/MCTP1/TLR2/DYSF/LRPAP1/ADIPOQ/ATG3/NR1H3/PRKD1/ATXN2/MTMR2/SH3GL3/LILRB1	14
BP	GO:0006767	water-soluble vitamin metabolic process	17/2112	88/18670	0.01871	0.08148	0.05887	ENPP1/KYNU/CYB5R3/MTHFD2/PC/MCCC1/SLC2A3/PCCA/KMO/RGN/CD320/CTRB2/SLC23A2/GSTO1/LMBRD1/SLC5A6/TKTL1	17
BP	GO:0051205	protein insertion into membrane	11/2112	49/18670	0.01897	0.08254	0.05964	TFDP2/RTP4/GZMB/BID/EGFR/TP63/PMAIP1/UBL4A/TP53BP2/TP53/MOAP1	11
BP	GO:0055006	cardiac cell development	18/2112	95/18670	0.01914	0.08291	0.05991	SGCB/BMP4/IGF1/MYH10/TGFBR3/CDK1/SORBS2/PDLIM5/SGCD/NOTCH1/CCNB1/HEY2/SLC8A1/PAK1/AKAP13/MYH11/LMNA/ALPK3	18
BP	GO:0061326	renal tubule development	18/2112	95/18670	0.01914	0.08291	0.05991	BMP4/STAT1/SOX9/GLI3/SIX1/SIX2/YAP1/FGF2/ACAT1/PBX1/DCHS1/NOTCH1/WWTR1/FAT4/PKD2/POU3F3/HOXA11/AHI1	18
BP	GO:0051924	regulation of calcium ion transport	40/2112	254/18670	0.01917	0.08291	0.05991	CCL5/CXCL9/XCL1/CORO1A/LILRB2/CXCR4/SRI/CACNA2D1/ANK2/ICAM1/DYSF/GEM/CXCL10/PTPN6/TRPV2/PLCG2/BAK1/CCR1/PLN/TRPC1/CD19/ATP1B1/IL16/RGN/ATP1A2/CXCL11/SLC8A1/FGF14/P2RY6/APLNR/CYBA/LYN/PKD2/GSTO1/MYLK/GSTM2/CCL2/CASK/PML/LILRB1	40
BP	GO:0071466	cellular response to xenobiotic stimulus	30/2112	180/18670	0.01919	0.08291	0.05991	CDO1/NQO1/EPHX1/FMO2/GSTM5/GSTM3/GSTA4/ICAM1/BPHL/EGFR/CYB5R3/AKR1C1/GHR/CCNA2/PCK1/FOXO1/ARNT/SLC8A1/HSP90AB1/AOC2/PTGS1/RYR3/RB1/CYP46A1/GSTO1/AOC3/CFLAR/GSTM2/AKR7A2/EPHX2	30
BP	GO:0002675	positive regulation of acute inflammatory response	8/2112	31/18670	0.01924	0.08291	0.05991	CCR7/ADAM8/HLA-E/TAC1/IL6ST/BTK/IL6/IL1B	8
BP	GO:0006658	phosphatidylserine metabolic process	8/2112	31/18670	0.01924	0.08291	0.05991	PLA2G2D/SERINC3/LPCAT3/PLA2G12A/PLA1A/SERINC1/PTDSS1/PLSCR1	8
BP	GO:0035767	endothelial cell chemotaxis	8/2112	31/18670	0.01924	0.08291	0.05991	CXCL13/FGF18/PRKD2/FGF2/NOTCH1/HSPB1/PRKD1/KDR	8
BP	GO:0043457	regulation of cellular respiration	8/2112	31/18670	0.01924	0.08291	0.05991	CBFA2T3/CDK1/VCP/IFNG/CCNB1/PIK3CA/SLC25A23/PINK1	8
BP	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity	8/2112	31/18670	0.01924	0.08291	0.05991	CCND2/EGFR/CCNT1/CKS2/CCNB1/CCND1/CKS1B/PKD2	8
BP	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process	8/2112	31/18670	0.01924	0.08291	0.05991	CHST15/CHST3/DCN/BGN/CSPG4/CHST11/VCAN/UGDH	8
BP	GO:1903393	positive regulation of adherens junction organization	8/2112	31/18670	0.01924	0.08291	0.05991	SFRP1/MAPRE2/ITGB1BP1/SMAD3/MYOC/PPM1F/KDR/COL16A1	8
BP	GO:1904064	positive regulation of cation transmembrane transport	25/2112	144/18670	0.01929	0.08291	0.05991	CXCL9/XCL1/CCR2/SRI/CACNA2D1/ANK2/FXYD1/CXCL10/PLCG2/KCNJ2/TRPC1/CD19/ATP1B1/IFNG/RGN/CXCL11/FGF14/P2RY6/APLNR/PINK1/TESC/PKD2/GSTO1/GSTM2/CCL2	25
BP	GO:0090287	regulation of cellular response to growth factor stimulus	45/2112	292/18670	0.01947	0.08291	0.05991	CXCL13/SFRP1/GDF5/BMP4/CDKN1C/FGF18/SKI/PRKCB/HTRA1/SULF1/ADAMTSL2/PRKD2/TWSG1/FGF2/TGFBR3/CREBBP/DCN/NEO1/GLG1/CHST11/PMEPA1/FZD4/CYFIP2/SMAD3/TNMD/LDLRAD4/NOTCH1/NBL1/ARNT/TOB1/CHRDL1/HSP90AB1/MYO1C/FGF9/TGFB3/FST/FERMT1/HIPK2/FSTL3/DKK3/CFLAR/TP53/CASK/IL1B/CDH5	45
BP	GO:0016570	histone modification	66/2112	454/18670	0.01947	0.08291	0.05991	NAP1L2/EYA4/ING3/SKI/PRKCB/SKP1/IRF4/AUTS2/SIRT7/EYA2/VRK1/BAZ1A/JAK2/HDAC4/PRKD2/GATA2/UBE2B/USP3/CREBBP/KMT2A/TAF7/CDK1/CCNA2/EZH2/PER2/RPS6KA4/LEF1/DNMT1/ATRX/BRD4/PAX5/CCNB1/EID1/MECP2/MTF2/MSL3/PPM1F/MBIP/RLF/GFI1/KAT6B/SPI1/NIPBL/PAF1/PINK1/SUZ12/PHF10/SMYD2/JARID2/LMNA/AURKB/RSF1/KDM7A/MORF4L1/PRKD1/CUL4B/PRMT1/SETMAR/EZH1/WAC/TP53/USP7/AURKA/KDM2A/TBL1X/IL1B	66
BP	GO:0045687	positive regulation of glial cell differentiation	10/2112	43/18670	0.01949	0.08291	0.05991	TNFRSF1B/CXCR4/ZNF365/TLR2/DAG1/ASPA/PTN/NOTCH1/IL6ST/TENM4	10
BP	GO:0071364	cellular response to epidermal growth factor stimulus	10/2112	43/18670	0.01949	0.08291	0.05991	SOX9/FOXC1/EGFR/ERBB2/SKAP1/ZPR1/PTPN11/ZFP36L1/CFLAR/ZFP36L2	10
BP	GO:1901658	glycosyl compound catabolic process	10/2112	43/18670	0.01949	0.08291	0.05991	TYMP/NT5E/UPP1/APOBEC3G/APOBEC3B/ADA/FUCA1/PNP/GLA/ENTPD4	10
BP	GO:0017157	regulation of exocytosis	35/2112	217/18670	0.01952	0.08291	0.05991	CCR2/HLA-F/RAC2/PREPL/RAB8A/PRKCB/PFN2/ITGB2/IL4R/LGALS9/GATA2/FGR/NLGN1/IL13RA2/RAB33B/HTR2A/CHRNA5/RAB27A/NOTCH1/IFNG/STXBP2/MICAL1/SYT17/STX4/SYK/VAMP2/STXBP1/BACE1/FER/GAB2/LYN/DVL1/CASK/P2RY4/CADPS	35
BP	GO:0003183	mitral valve morphogenesis	4/2112	10/18670	0.01956	0.08291	0.05991	BMPR1A/DCHS1/NOTCH1/ACVR1	4
BP	GO:0006002	fructose 6-phosphate metabolic process	4/2112	10/18670	0.01956	0.08291	0.05991	NFE2L1/GFPT1/GFPT2/TALDO1	4
BP	GO:0030647	aminoglycoside antibiotic metabolic process	4/2112	10/18670	0.01956	0.08291	0.05991	AKR1C3/AKR1B1/AKR1C1/AKR7A2	4
BP	GO:0045625	regulation of T-helper 1 cell differentiation	4/2112	10/18670	0.01956	0.08291	0.05991	CCL19/IL4R/RIPK2/CD80	4
BP	GO:0046642	negative regulation of alpha-beta T cell proliferation	4/2112	10/18670	0.01956	0.08291	0.05991	XCL1/LGALS9/TNFRSF14/TWSG1	4
BP	GO:0048340	paraxial mesoderm morphogenesis	4/2112	10/18670	0.01956	0.08291	0.05991	FOXC1/BMPR1A/LEF1/SMAD3	4
BP	GO:0051255	spindle midzone assembly	4/2112	10/18670	0.01956	0.08291	0.05991	KIF4A/RACGAP1/AURKB/KIF23	4
BP	GO:0051901	positive regulation of mitochondrial depolarization	4/2112	10/18670	0.01956	0.08291	0.05991	DCN/MYOC/PARP1/KDR	4
BP	GO:0060068	vagina development	4/2112	10/18670	0.01956	0.08291	0.05991	AXL/BAK1/RBP4/MERTK	4
BP	GO:0060513	prostatic bud formation	4/2112	10/18670	0.01956	0.08291	0.05991	BMP4/AR/SULF1/TP63	4
BP	GO:0070341	fat cell proliferation	4/2112	10/18670	0.01956	0.08291	0.05991	PID1/FTO/GATA2/PER2	4
BP	GO:0070344	regulation of fat cell proliferation	4/2112	10/18670	0.01956	0.08291	0.05991	PID1/FTO/GATA2/PER2	4
BP	GO:0072641	type I interferon secretion	4/2112	10/18670	0.01956	0.08291	0.05991	IFIH1/DDX58/MMP12/LILRB1	4
BP	GO:0098722	asymmetric stem cell division	4/2112	10/18670	0.01956	0.08291	0.05991	ZBTB16/SOX5/ETV5/FGF13	4
BP	GO:1902237	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	4/2112	10/18670	0.01956	0.08291	0.05991	SERINC3/PTPN2/PMAIP1/DDIT3	4
BP	GO:1903862	positive regulation of oxidative phosphorylation	4/2112	10/18670	0.01956	0.08291	0.05991	CDK1/VCP/CCNB1/PINK1	4
BP	GO:2000109	regulation of macrophage apoptotic process	4/2112	10/18670	0.01956	0.08291	0.05991	CCL5/CCR5/NOD2/IRF7	4
BP	GO:2000271	positive regulation of fibroblast apoptotic process	4/2112	10/18670	0.01956	0.08291	0.05991	SFRP1/BID/STK17B/TP63	4
BP	GO:0051261	protein depolymerization	20/2112	109/18670	0.01961	0.08291	0.05991	ADD3/TMOD1/GAK/CKAP2/KIF18B/FGF13/PLEK/ASPH/KIF2C/DSTN/LMOD1/MICAL1/CAMSAP2/MAP1B/CFL1/CAPZA1/VILL/WDR1/SPTBN1/GSN	20
BP	GO:0070588	calcium ion transmembrane transport	48/2112	315/18670	0.01965	0.08291	0.05991	CXCL9/CCR5/XCL1/LCK/PTPRC/YME1L1/CORO1A/PLCE1/CCL19/SRI/CACNA2D1/ANK2/CCR7/DYSF/HTR2B/GEM/CXCL10/PTPN6/FGF2/TRPV2/PLCG2/CCL21/PLN/AFG3L2/MICU1/TRPC1/HTR2A/CD19/ATP1B1/RGN/ATP1A2/CXCL11/SLC8A1/FGF14/P2RY6/APLNR/SLC25A23/DDIT3/RYR3/CYBA/LYN/PANX1/PKD2/GSTO1/GSTM2/ITGAV/TRPM6/ATP2A3	48
BP	GO:0007431	salivary gland development	9/2112	37/18670	0.01965	0.08291	0.05991	SEMA3A/FGF7/TWSG1/EGFR/DAG1/NFIB/HGF/TGFB3/TGM2	9
BP	GO:0033280	response to vitamin D	9/2112	37/18670	0.01965	0.08291	0.05991	SFRP1/PENK/IL15/PIM1/KANK2/CXCL10/TRIM24/PTN/ALPL	9
BP	GO:0046006	regulation of activated T cell proliferation	9/2112	37/18670	0.01965	0.08291	0.05991	IGF1/LGALS9/BTN2A2/PDCD1LG2/ICOSLG/IL18/IGFBP2/LRRC32/IL2RA	9
BP	GO:0048846	axon extension involved in axon guidance	9/2112	37/18670	0.01965	0.08291	0.05991	SEMA4A/SEMA4D/SEMA3A/RYK/SEMA3F/MEGF8/SEMA4F/SEMA3E/SEMA6B	9
BP	GO:0060236	regulation of mitotic spindle organization	9/2112	37/18670	0.01965	0.08291	0.05991	TACC3/PLK1/TPX2/BORA/TPR/MAP9/STAG2/CHMP2B/CHMP1B	9
BP	GO:1902284	neuron projection extension involved in neuron projection guidance	9/2112	37/18670	0.01965	0.08291	0.05991	SEMA4A/SEMA4D/SEMA3A/RYK/SEMA3F/MEGF8/SEMA4F/SEMA3E/SEMA6B	9
BP	GO:1900180	regulation of protein localization to nucleus	21/2112	116/18670	0.01968	0.08291	0.05991	PIK3R1/BMP4/ZIC1/GLI3/ANGPT1/HCLS1/PLK1/CD36/TPR/CDK1/LILRB4/ZPR1/SMAD3/MFHAS1/ECT2/LEP/IFNG/PARP1/LMNA/FERMT1/DCLK1	21
BP	GO:0072524	pyridine-containing compound metabolic process	32/2112	195/18670	0.01969	0.08291	0.05991	IGF1/NT5E/IDO1/ZBTB20/FMO2/KYNU/SLC2A6/CBFA2T3/NUP93/HDAC4/HK3/ALDOC/MPC2/IDH2/TPR/NUP160/RPIA/HTR2A/PGD/VCP/IFNG/ARNT/KMO/PNP/MDH1/CD38/MPC1/NUP88/NUP50/TP53/TALDO1/GPD1L	32
BP	GO:0002753	cytoplasmic pattern recognition receptor signaling pathway	13/2112	62/18670	0.01974	0.08291	0.05991	TNFAIP3/BIRC3/NOD2/IRF7/IFIH1/RIPK2/TSPAN6/NFKBIA/DDX58/DDX60/IKBKG/PTPN22/NOD1	13
BP	GO:0007585	respiratory gaseous exchange	13/2112	62/18670	0.01974	0.08291	0.05991	CSF2RB/FTO/NDN/PBX3/PASK/NLGN1/CHST11/ATP1A2/MECP2/SLC5A3/ADH5/FUT8/HOXA5	13
BP	GO:0032835	glomerulus development	13/2112	62/18670	0.01974	0.08291	0.05991	BMP4/PLCE1/FOXC1/ANGPT1/SULF1/PDGFD/MAGI2/NOTCH1/PECAM1/ADIPOQ/WWTR1/CFLAR/GPR4	13
BP	GO:0055025	positive regulation of cardiac muscle tissue development	13/2112	62/18670	0.01974	0.08291	0.05991	BMP4/IGF1/PIM1/ZFPM2/BMPR1A/YAP1/FGF2/TGFBR3/CDK1/NOTCH1/CCNB1/HEY2/FGF9	13
BP	GO:1902686	mitochondrial outer membrane permeabilization involved in programmed cell death	13/2112	62/18670	0.01974	0.08291	0.05991	TFDP2/GZMB/BID/EYA2/TMEM14A/BAK1/TP63/PMAIP1/SLC25A5/TP53BP2/TP53/BNIP3L/MOAP1	13
BP	GO:0016137	glycoside metabolic process	6/2112	20/18670	0.01988	0.08323	0.06014	AKR1C3/AKR1B1/AKR1C1/FUCA1/GLA/AKR7A2	6
BP	GO:0035458	cellular response to interferon-beta	6/2112	20/18670	0.01988	0.08323	0.06014	AIM2/IRF1/STAT1/NDUFA13/MNDA/UBE2G2	6
BP	GO:0060216	definitive hemopoiesis	6/2112	20/18670	0.01988	0.08323	0.06014	RBFOX2/MEIS1/GATA2/TGFBR3/ADAR/ZFP36L2	6
BP	GO:0070262	peptidyl-serine dephosphorylation	6/2112	20/18670	0.01988	0.08323	0.06014	PPP2CA/PPP3CA/PPP1R16B/PPP2CB/PPP1CA/PPM1F	6
BP	GO:1900017	positive regulation of cytokine production involved in inflammatory response	6/2112	20/18670	0.01988	0.08323	0.06014	MYD88/NOD2/GPSM3/CLEC7A/CD6/TLR6	6
BP	GO:0051169	nuclear transport	52/2112	346/18670	0.02002	0.08375	0.06051	PIK3R1/BMP4/ZIC1/PTPN14/GLI3/PPP3CA/ANGPT1/HCLS1/MX2/MALT1/CD36/NUP93/SIX2/XPO6/IFI27/CPSF6/TPR/BARD1/AHCYL1/TCF7L2/NFKBIA/NUP160/ZPR1/SMAD3/PTPN11/ARNTL/ECT2/LEP/IFNG/THOC2/SYK/FGF9/AKAP13/SNRPB/DDX39A/IPO7/KPNA2/LMNA/FERMT1/HMGA1/NUP88/THOC1/NUP50/TP53/KHDRBS1/HEATR3/THOC6/IL1B/MMP12/PML/XPO4/PSIP1	52
BP	GO:1903046	meiotic cell cycle process	31/2112	188/18670	0.02015	0.08422	0.06085	ASPM/PTTG1/PTTG3P/BUB1/NCAPD2/GOLGA2/PLK1/UBE2B/NCAPH/CDC25B/BUB1B/DAZL/TOP2A/MYBL1/RMI1/ATRX/CKS2/STAG3/TERF1/FBXO5/REC8/TTK/CDC20/TUBG2/ERCC1/SMC4/ACTR3/TRIP13/CCNE2/AURKA/ACTR2	31
BP	GO:0030279	negative regulation of ossification	16/2112	82/18670	0.02024	0.08448	0.06104	ENPP1/SFRP1/IGFBP5/SOX9/SEMA4D/LTBP3/SKI/HDAC4/TWSG1/SRGN/CCR1/ID3/LRP5/SMAD3/NOTCH1/TOB1	16
BP	GO:0097581	lamellipodium organization	16/2112	82/18670	0.02024	0.08448	0.06104	WASF3/PLEKHO1/RAC2/ARPIN/AUTS2/HDAC4/PDPN/WAS/ABLIM1/KANK1/CTTN/RHOD/FER/WASF2/S1PR1/VAV3	16
BP	GO:0001505	regulation of neurotransmitter levels	53/2112	354/18670	0.02033	0.0848	0.06127	CLU/GCH1/NQO1/ALDH7A1/PREPL/MCTP1/PRKCB/TLR2/PFN2/HBB/ITGB2/ICAM1/JAK2/CD36/SLC18A2/SLC29A1/SNCAIP/DDAH2/SLC1A3/CLEC7A/NLGN1/CX3CR1/PER2/MAOA/ARL6IP5/NAALAD2/HTR2A/CHRNA5/SMAD3/IFNG/KMO/RGN/ATP1A2/SYT17/HSP90AB1/STX4/VAMP2/STXBP1/BACE1/MAOB/SLC29A2/SNCG/GLA/PKD2/NAAA/DVL1/CASK/TLR6/IL1B/PTX3/P2RY4/ALDH5A1/CADPS	53
BP	GO:0097306	cellular response to alcohol	17/2112	89/18670	0.02077	0.08656	0.06254	SFRP1/LRP6/INHBA/AKR1C3/NFE2L1/DAG1/BLM/MAP4K1/LANCL2/EFNA5/PTGFR/PTGER4/CCL7/P2RY6/SPI1/FOXO3/P2RY4	17
BP	GO:0016064	immunoglobulin mediated immune response	35/2112	218/18670	0.0208	0.08656	0.06254	TRBC1/XCL1/PTPRC/IL27RA/CLU/TLR8/BATF/CD74/TCIRG1/IL4R/IRF7/CD40/TFRC/HLA-E/PTPN6/CR1/IGHM/IGLL5/CD226/TBX21/IL13RA2/CD27/CD40LG/CD19/IGLC1/IGLV1-44/C7/BTK/IGHG1/INPP5D/CD81/ERCC1/THOC1/CR2/C6	35
BP	GO:0006749	glutathione metabolic process	12/2112	56/18670	0.02088	0.08656	0.06254	GSTM5/NFE2L1/GSTM3/GSTA4/CNDP2/HPGDS/SOD1/GPX4/GLO1/HAGH/GSTM2/ALDH5A1	12
BP	GO:0010332	response to gamma radiation	12/2112	56/18670	0.02088	0.08656	0.06254	PTPRC/CRYAB/YAP1/CXCL10/BAK1/NOX4/CCL7/PARP1/CYBA/TP53/PML/GTF2H5	12
BP	GO:0060688	regulation of morphogenesis of a branching structure	12/2112	56/18670	0.02088	0.08656	0.06254	SFRP1/BMP4/SOX9/FGF7/AR/SULF1/SIX1/SIX2/SHOX2/ETV5/HGF/BCL11A	12
BP	GO:0000098	sulfur amino acid catabolic process	5/2112	15/18670	0.02093	0.08656	0.06254	CDO1/PCYOX1/CBS/MAT1A/TXN2	5
BP	GO:0034349	glial cell apoptotic process	5/2112	15/18670	0.02093	0.08656	0.06254	PRKCH/AKAP12/RB1/TP53/CCL2	5
BP	GO:0045410	positive regulation of interleukin-6 biosynthetic process	5/2112	15/18670	0.02093	0.08656	0.06254	CD74/CLEC7A/SYK/TLR6/IL1B	5
BP	GO:0060253	negative regulation of glial cell proliferation	5/2112	15/18670	0.02093	0.08656	0.06254	SKI/IDH2/PTN/NOTCH1/RNF10	5
BP	GO:1901841	regulation of high voltage-gated calcium channel activity	5/2112	15/18670	0.02093	0.08656	0.06254	SRI/CACNA2D1/DYSF/GEM/FGF14	5
BP	GO:1902969	mitotic DNA replication	5/2112	15/18670	0.02093	0.08656	0.06254	LIG1/CDC45/GINS1/MCM2/MCM4	5
BP	GO:0042698	ovulation cycle	14/2112	69/18670	0.02093	0.08656	0.06254	PLEKHA1/INHBA/AXL/TIMP4/PAM/SGPL1/EGFR/PTN/FZD4/LEP/TGFB3/FOXO3/NRIP1/PTX3	14
BP	GO:0086003	cardiac muscle cell contraction	14/2112	69/18670	0.02093	0.08656	0.06254	SRI/CACNA2D1/ANK2/KCNJ5/PLN/SGCD/KCNJ2/SCN1B/KCNJ8/DSC2/ATP1A2/GJC1/SNTA1/GPD1L	14
BP	GO:0071897	DNA biosynthetic process	32/2112	196/18670	0.02106	0.08704	0.06289	LIG1/PRKCQ/DTL/UBE2L6/PRKD2/FGF2/SPHK1/HGF/KCNK2/NOX4/NEK7/REV3L/RFC3/NEK2/VCP/RGN/TERF1/HSP90AB1/ADIPOQ/PARP4/CENPF/TYMS/POLE2/AURKB/USP10/TK2/TK1/TP53/PARM1/ISG15/PARN/DNAJC2	32
BP	GO:0008584	male gonad development	24/2112	138/18670	0.02112	0.08715	0.06297	KITLG/PLEKHA1/SFRP1/ASPM/HOXA10/SOX9/SEMA3A/INHBA/AKR1C3/RHOBTB3/TNFSF10/AR/ZFPM2/SGPL1/ICAM1/BCL2L2/ATRX/CCND1/FGF9/REC8/FSTL3/REN/ERCC1/HOXA11	24
BP	GO:1990823	response to leukemia inhibitory factor	18/2112	96/18670	0.02114	0.08715	0.06297	SPOCK2/PCOLCE2/ICAM1/TFRC/PCOLCE/FZD4/MTF2/KAT6B/B3GNT2/MRPL15/MPC1/JARID2/SLC25A5/ADAM23/SNX10/SBNO2/GFPT2/PML	18
BP	GO:1990830	cellular response to leukemia inhibitory factor	18/2112	96/18670	0.02114	0.08715	0.06297	SPOCK2/PCOLCE2/ICAM1/TFRC/PCOLCE/FZD4/MTF2/KAT6B/B3GNT2/MRPL15/MPC1/JARID2/SLC25A5/ADAM23/SNX10/SBNO2/GFPT2/PML	18
BP	GO:2001169	regulation of ATP biosynthetic process	18/2112	96/18670	0.02114	0.08715	0.06297	PID1/IGF1/ZBTB20/SLC2A6/CBFA2T3/NUP93/HDAC4/TPR/NUP160/HTR2A/VCP/IFNG/ARNT/PARP1/PINK1/NUP88/NUP50/TP53	18
BP	GO:1901617	organic hydroxy compound biosynthetic process	42/2112	271/18670	0.02143	0.08818	0.06371	LBR/GCH1/PLCE1/AKR1C3/ABCG1/ACOX2/PMVK/PCBD1/AKR1B1/CYB5R3/FGF2/SPHK1/PLCG2/PLEK/FAXDC2/ERLIN1/SP1/PCK1/PER2/SOD1/ACACB/CYB5R1/NFKB1/TRPC1/SC5D/HRH1/LEP/IFNG/NFYA/P2RY6/ERLIN2/GFI1/PPIP5K1/OSBPL1A/MBTPS2/SLC27A5/CYP46A1/OSBPL9/DKK3/PTH1R/TP53/IL1B	42
BP	GO:0007098	centrosome cycle	22/2112	124/18670	0.02145	0.08818	0.06371	CETN2/GOLGA2/PLK1/KIF11/KIF3B/CDK1/MAP9/CEP135/MCPH1/ARHGEF10/NEK2/PLK2/CETN3/CEP85/CHMP2B/CEP68/CEP63/PKD2/CCNF/AURKA/CHMP1B/STIL	22
BP	GO:0019751	polyol metabolic process	22/2112	124/18670	0.02145	0.08818	0.06371	GK/GCH1/PLCE1/DYSF/PCBD1/AKR1B1/FGF2/SPHK1/PLCG2/PLEK/PCK1/INPP1/HRH1/LEP/MECP2/NUDT11/SLC5A3/P2RY6/PPIP5K1/INPP5D/PTH1R/MTMR2	22
BP	GO:0051101	regulation of DNA binding	22/2112	124/18670	0.02145	0.08818	0.06371	GZMA/IGF1/SRI/FOXC1/SKI/IRF4/JAK2/HJURP/ID3/PER2/NFKBIA/NEK2/LEF1/IFNG/HEY2/PARP1/NIPBL/DDIT3/RSF1/RB1/HIPK2/HEY1	22
BP	GO:0010508	positive regulation of autophagy	21/2112	117/18670	0.02151	0.08839	0.06386	PIP4K2B/RIPK2/DCN/TRIM21/FOXO1/PLK2/IFNG/IKBKG/TRIM22/PINK1/PIP4K2A/FOXO3/PRKD1/SESN1/NOD1/EPM2A/KDR/FYCO1/WAC/BNIP3L/PIM2	21
BP	GO:0019362	pyridine nucleotide metabolic process	31/2112	189/18670	0.02157	0.0885	0.06395	IGF1/NT5E/IDO1/ZBTB20/FMO2/KYNU/SLC2A6/CBFA2T3/NUP93/HDAC4/HK3/ALDOC/MPC2/IDH2/TPR/NUP160/RPIA/HTR2A/PGD/VCP/IFNG/ARNT/KMO/MDH1/CD38/MPC1/NUP88/NUP50/TP53/TALDO1/GPD1L	31
BP	GO:0046496	nicotinamide nucleotide metabolic process	31/2112	189/18670	0.02157	0.0885	0.06395	IGF1/NT5E/IDO1/ZBTB20/FMO2/KYNU/SLC2A6/CBFA2T3/NUP93/HDAC4/HK3/ALDOC/MPC2/IDH2/TPR/NUP160/RPIA/HTR2A/PGD/VCP/IFNG/ARNT/KMO/MDH1/CD38/MPC1/NUP88/NUP50/TP53/TALDO1/GPD1L	31
BP	GO:0042593	glucose homeostasis	38/2112	241/18670	0.02159	0.08852	0.06396	PIK3R1/IGFBP5/ZBTB20/SRI/NUCKS1/OXCT1/PPP3CA/PTPN2/OAS1/ICAM1/HK3/KLF7/MPC2/NMB/CYB5R4/TCF7L2/PCK1/LRP5/NOX4/FOXO1/RMI1/EFNA5/PTPN11/RBP4/LEP/SSTR5/PIK3CA/ADIPOQ/STX4/FABP5/PDK4/SYBU/FOXO3/CYBA/CEBPA/RAB11FIP2/ZNF236/GPR27	38
BP	GO:0046785	microtubule polymerization	15/2112	76/18670	0.02184	0.0895	0.06466	TPPP3/GOLGA2/FGF13/ZNF207/TUBB4A/MAP7D3/MECP2/TERF1/PAK1/FBXO5/CAMSAP2/MAP1B/CLIP3/TUBG2/CDH5	15
BP	GO:0001961	positive regulation of cytokine-mediated signaling pathway	11/2112	50/18670	0.02191	0.08961	0.06474	CXCR4/CD74/AXL/IRF7/RIPK2/TXK/CASP1/GFI1/CASP4/IL1R1/MMP12	11
BP	GO:0034656	nucleobase-containing small molecule catabolic process	11/2112	50/18670	0.02191	0.08961	0.06474	TYMP/NT5E/GALT/UPP1/APOBEC3G/APOBEC3B/ADA/ENTPD7/PNP/ENTPD1/ENTPD4	11
BP	GO:0045666	positive regulation of neuron differentiation	55/2112	371/18670	0.02191	0.08961	0.06474	NDNF/EPHA3/GDF5/S100A9/BMP4/NAP1L2/DLG5/CXCR4/SEMA4D/NTRK2/CDON/LPAR1/PTPRD/ITSN1/TIMP2/COBL/SHOX2/GATA2/MMD/TUBB2B/ETV5/TRPV2/CREB3L2/HGF/MAGI2/NLGN1/EZH2/SOCS2/SCARF1/CAMK1D/PTN/FZD4/EFNA5/SCN1B/FEZ1/ECT2/GDI1/NBL1/SERPINI1/SYT17/PAK1/DPYSL3/SCARB2/CHODL/MAP1B/MEGF8/PRKD1/LYN/DVL1/CFLAR/FEZF2/GDPD5/SH3GL3/ACTR2/BRINP1	55
BP	GO:0045766	positive regulation of angiogenesis	33/2112	204/18670	0.02193	0.08964	0.06476	FGF18/CXCR4/PRKCB/ITGB2/CD40/PRKD2/ANXA3/GATA2/FGF2/SPHK1/CXCL8/HGF/SP1/CX3CR1/PPP1R16B/RRAS/HYAL1/ANGPTL4/PLK2/AGTR1/APLNR/ITGAX/HSPB1/AKT3/HSPB6/VEGFB/PRKD1/HIPK2/KDR/IL1B/CDH5/C6/CTSH	33
BP	GO:0008217	regulation of blood pressure	30/2112	182/18670	0.02208	0.09016	0.06514	GCH1/NPY1R/EMP2/HBB/NPR2/AR/ERAP2/TAC1/LRP5/SOD1/SNX5/SMAD3/CORO2B/NAV2/LEP/AGTR1/ATP1A2/OR51E2/MECP2/CPA3/ADIPOQ/EDNRB/PTGS1/ADH5/CYBA/REN/NPR3/ACSM3/SLC2A5/EPHX2	30
BP	GO:0062013	positive regulation of small molecule metabolic process	26/2112	153/18670	0.02223	0.09033	0.06527	PID1/IGF1/ZBTB20/ABCG1/CD74/PTPN2/CDK1/NFKB1/PMAIP1/HTR2A/FOXO1/HRH1/VCP/IFNG/ARNT/CCNB1/RGN/ADIPOQ/P2RY6/SORBS1/PINK1/NR1H3/GUCA1A/PTH1R/IL1B/ELOVL5	26
BP	GO:0030318	melanocyte differentiation	7/2112	26/18670	0.02224	0.09033	0.06527	ENPP1/KITLG/MREG/GLI3/RAB27A/OR51E2/EDNRB	7
BP	GO:0050926	regulation of positive chemotaxis	7/2112	26/18670	0.02224	0.09033	0.06527	SCG2/CXCL8/SMAD3/IL16/VEGFB/KDR/S1PR1	7
BP	GO:0051497	negative regulation of stress fiber assembly	7/2112	26/18670	0.02224	0.09033	0.06527	DLC1/WAS/CORO2B/MYOC/WASF2/S1PR1/PFN1	7
BP	GO:0060740	prostate gland epithelium morphogenesis	7/2112	26/18670	0.02224	0.09033	0.06527	SFRP1/BMP4/SOX9/AR/SULF1/TP63/NOTCH1	7
BP	GO:0099560	synaptic membrane adhesion	7/2112	26/18670	0.02224	0.09033	0.06527	PTPRD/NLGN1/PTPRF/PCDH17/PTPRS/EFNA5/GPC4	7
BP	GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	7/2112	26/18670	0.02224	0.09033	0.06527	TFDP2/GZMB/BID/TP63/PMAIP1/TP53BP2/TP53	7
BP	GO:1900740	positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	7/2112	26/18670	0.02224	0.09033	0.06527	TFDP2/GZMB/BID/TP63/PMAIP1/TP53BP2/TP53	7
BP	GO:0034394	protein localization to cell surface	13/2112	63/18670	0.02238	0.09078	0.06559	PIGK/CD247/FCN1/ANK2/EMP2/ANGPT1/FGF7/FBLN5/HSP90AB1/STX4/HFE/RIC3/GPD1L	13
BP	GO:0090181	regulation of cholesterol metabolic process	13/2112	63/18670	0.02238	0.09078	0.06559	ACADVL/ABCG1/PMVK/ERLIN1/SP1/SOD1/ACACB/SC5D/NFYA/ERLIN2/MBTPS2/ACADL/EPHX2	13
BP	GO:0006959	humoral immune response	53/2112	356/18670	0.0224	0.09084	0.06563	CXCL13/CXCL9/TRBC1/PTPRC/CCR2/S100A9/SCARA3/CLU/GPR183/FCN1/PSMB10/SLPI/CCL13/CCR7/GNLY/CXCL1/CFP/LYZ/CXCL10/HLA-E/PTPN6/PROS1/CXCL8/SH2D1A/CR1/IGHM/IGLL5/CFD/MS4A1/CD83/CD19/NOTCH1/CXCL3/PAX5/IFNG/IGLC1/CXCL11/IGLV1-44/C7/KRT6A/IL6/IGHG1/CXCL2/CXCL5/CXCL6/CFB/CD81/SPINK5/CCL2/IFNA1/IL1B/CR2/C6	53
BP	GO:1901879	regulation of protein depolymerization	16/2112	83/18670	0.02252	0.09124	0.06592	ADD3/TMOD1/CKAP2/FGF13/PLEK/ASPH/DSTN/LMOD1/CAMSAP2/MAP1B/CFL1/CAPZA1/VILL/WDR1/SPTBN1/GSN	16
BP	GO:0120032	regulation of plasma membrane bounded cell projection assembly	29/2112	175/18670	0.02257	0.09135	0.066	DYNC2LI1/RAC2/CCL19/CCR7/AUTS2/PFN2/MAP4/ICAM1/HDAC4/COBL/WASL/DZIP1/SH3YL1/CCL21/WAS/CDC42EP3/PLD1/NLGN1/CEP135/PPP1R16B/KANK1/RHOG/FNBP1L/ATG3/DPYSL3/TGFB3/FER/WASF2/PFN1	29
BP	GO:0006140	regulation of nucleotide metabolic process	25/2112	146/18670	0.02257	0.09135	0.066	PID1/IGF1/ZBTB20/SLC2A6/CBFA2T3/COX7A1/NUP93/HDAC4/TPR/CDK1/NUP160/HTR2A/VCP/IFNG/ARNT/CCNB1/PDK4/PARP1/SLC25A23/PINK1/GUCA1A/NUP88/NUP50/TP53/COX7A2	25
BP	GO:0006816	calcium ion transport	63/2112	434/18670	0.02264	0.09157	0.06616	CCL5/CXCL9/CCR5/XCL1/LCK/PTPRC/YME1L1/CORO1A/LILRB2/PLCE1/CXCR4/CCL19/SRI/CACNA2D1/ANK2/PPP3CA/CCR7/PRKCB/ICAM1/DYSF/HTR2B/GEM/CXCL10/PTPN6/FGF2/TRPV2/PLCG2/CCL21/BAK1/CCR1/PLN/AFG3L2/MICU1/MS4A1/TRPC1/HTR2A/CD19/ATP1B1/IL16/RGN/ATP1A2/CXCL11/SLC8A1/FGF14/P2RY6/APLNR/SLC25A23/DDIT3/RYR3/CYBA/LYN/PANX1/PKD2/GSTO1/MYLK/GSTM2/ITGAV/CCL2/CASK/TRPM6/PML/LILRB1/ATP2A3	63
BP	GO:0072511	divalent inorganic cation transport	70/2112	489/18670	0.02266	0.09158	0.06617	CCL5/CXCL9/CCR5/XCL1/LCK/PTPRC/YME1L1/CORO1A/LILRB2/PLCE1/CXCR4/CCL19/SRI/CACNA2D1/ANK2/PPP3CA/CCR7/PRKCB/ICAM1/DYSF/HTR2B/GEM/CXCL10/PTPN6/FGF2/TRPV2/MAGT1/PLCG2/CCL21/SLC39A8/BAK1/CCR1/PLN/AFG3L2/MICU1/KCNJ2/MS4A1/TRPC1/HTR2A/CD19/ATP1B1/IL16/IFNG/RGN/ATP1A2/CXCL11/SLC8A1/FGF14/P2RY6/APLNR/SLC25A23/CNNM2/SLC39A6/DDIT3/RYR3/CYBA/LYN/PANX1/PKD2/GSTO1/MYLK/SLC39A7/GSTM2/ITGAV/CCL2/CASK/TRPM6/PML/LILRB1/ATP2A3	70
BP	GO:0035307	positive regulation of protein dephosphorylation	10/2112	44/18670	0.02274	0.09173	0.06628	PTPRC/LILRB2/JAK2/DLC1/MAGI2/PPP1R16B/HSP90AB1/PINK1/CAMTA1/CDH5	10
BP	GO:0035850	epithelial cell differentiation involved in kidney development	10/2112	44/18670	0.02274	0.09173	0.06628	BMP4/STAT1/SIX2/YAP1/MAGI2/NOTCH1/ADIPOQ/WWTR1/FAT4/GPR4	10
BP	GO:1901028	regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	10/2112	44/18670	0.02274	0.09173	0.06628	TFDP2/GZMB/BID/TMEM14A/BAK1/TP63/PMAIP1/SLC25A5/TP53BP2/TP53	10
BP	GO:0031333	negative regulation of protein complex assembly	24/2112	139/18670	0.02288	0.09216	0.06659	CLU/ADD3/TMOD1/PFN2/CRYAB/TMSB10/TUBB4A/PMEPA1/LDLRAD4/KANK1/LMOD1/HEY2/PTGER4/DACT1/STXBP1/CRBN/CAPZA1/VILL/CLIP3/PFN1/SPTBN1/GSN/CDH5/THRA	24
BP	GO:0046546	development of primary male sexual characteristics	24/2112	139/18670	0.02288	0.09216	0.06659	KITLG/PLEKHA1/SFRP1/ASPM/HOXA10/SOX9/SEMA3A/INHBA/AKR1C3/RHOBTB3/TNFSF10/AR/ZFPM2/SGPL1/ICAM1/BCL2L2/ATRX/CCND1/FGF9/REC8/FSTL3/REN/ERCC1/HOXA11	24
BP	GO:0033500	carbohydrate homeostasis	38/2112	242/18670	0.02291	0.09221	0.06662	PIK3R1/IGFBP5/ZBTB20/SRI/NUCKS1/OXCT1/PPP3CA/PTPN2/OAS1/ICAM1/HK3/KLF7/MPC2/NMB/CYB5R4/TCF7L2/PCK1/LRP5/NOX4/FOXO1/RMI1/EFNA5/PTPN11/RBP4/LEP/SSTR5/PIK3CA/ADIPOQ/STX4/FABP5/PDK4/SYBU/FOXO3/CYBA/CEBPA/RAB11FIP2/ZNF236/GPR27	38
BP	GO:1990138	neuron projection extension	28/2112	168/18670	0.02305	0.09274	0.06701	SEMA4A/CXCR4/NDN/ITGA4/SEMA4D/SEMA3A/AUTS2/TRPV2/RYK/PTPRS/SEMA3F/CYFIP2/GDI1/SYT17/HSP90AB1/PAK1/CTTN/MAP1B/ARHGAP4/MEGF8/BCL11A/DPYSL2/SEMA4F/SEMA3E/DVL1/SEMA6B/AURKA/DCLK1	28
BP	GO:0042177	negative regulation of protein catabolic process	23/2112	132/18670	0.02314	0.09288	0.06711	LAMP3/NELL1/TIMP3/TIMP4/DYSF/MAD2L1/TIMP2/EGFR/GABARAPL2/SMAD3/HSP90AB1/HFE/UBE2J1/HIPK2/BAG5/ALAD/WAC/PBK/ATRAID/USP7/CAMLG/UBE2G2/PML	23
BP	GO:0060047	heart contraction	43/2112	280/18670	0.02317	0.09288	0.06711	GCH1/CXCR4/SRI/SEMA3A/CACNA2D1/ANK2/KCNK1/NPR2/FXYD1/JAK2/FXYD6/HDAC4/HBEGF/ADA/KCNJ5/TAC1/ADORA3/AHCYL1/PLN/ASPH/SOD1/SGCD/KCNJ2/TRPC1/ATP1B1/SCN1B/IRX5/KCNJ8/DSC2/ATP1A2/PIK3CA/HEY2/SLC8A1/POPDC2/RYR3/VEGFB/GSTO1/GJC1/GSTM2/SNTA1/THRA/GPD1L/ATP2A3	43
BP	GO:0038128	ERBB2 signaling pathway	8/2112	32/18670	0.02318	0.09288	0.06711	CPNE3/PIK3R1/BTC/EGFR/HBEGF/ERBB2/MYOC/PIK3CA	8
BP	GO:0055094	response to lipoprotein particle	8/2112	32/18670	0.02318	0.09288	0.06711	MYD88/ITGB2/CD36/NPC1/CD9/SYK/CD81/TLR6	8
BP	GO:0071295	cellular response to vitamin	8/2112	32/18670	0.02318	0.09288	0.06711	SFRP1/PENK/IL15/PIM1/KANK2/TRIM24/PTN/LEP	8
BP	GO:0009225	nucleotide-sugar metabolic process	9/2112	38/18670	0.02324	0.09288	0.06711	GALT/EXTL2/UGDH/NANS/NAGK/GFPT1/UGP2/FUT8/GFPT2	9
BP	GO:0035329	hippo signaling	9/2112	38/18670	0.02324	0.09288	0.06711	DLG5/YAP1/AMOTL2/DCHS1/MOB3B/WWTR1/FAT4/NPHP4/TEAD4	9
BP	GO:0046825	regulation of protein export from nucleus	9/2112	38/18670	0.02324	0.09288	0.06711	PTPN14/IFI27/TPR/BARD1/TCF7L2/PTPN11/TP53/IL1B/XPO4	9
BP	GO:0050716	positive regulation of interleukin-1 secretion	9/2112	38/18670	0.02324	0.09288	0.06711	AIM2/TLR8/CCL19/LGALS9/NOD2/RIPK2/CASP1/PANX1/NLRP3	9
BP	GO:0071604	transforming growth factor beta production	9/2112	38/18670	0.02324	0.09288	0.06711	XCL1/LTBP3/CD200/LGALS9/LUM/SMAD3/HSP90AB1/LRRC32/ITGAV	9
BP	GO:0007044	cell-substrate junction assembly	18/2112	97/18670	0.02331	0.09303	0.06721	SFRP1/EPHA3/LIMCH1/ITGB1BP1/FERMT2/TNS1/DLC1/EFNA5/SMAD3/CORO2B/MYOC/PPM1F/TRIP6/SORBS1/CTTN/RHOD/KDR/COL16A1	18
BP	GO:1902882	regulation of response to oxidative stress	18/2112	97/18670	0.02331	0.09303	0.06721	GCH1/MCTP1/ACOX2/OXR1/CD36/FBLN5/LANCL1/HGF/SOD1/RGN/PARP1/HSPB1/PINK1/FOXO3/SESN1/BAG5/FUT8/TLR6	18
BP	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	19/2112	104/18670	0.02347	0.09364	0.06765	TNFAIP3/BMP4/IGF1/EYA4/TNFSF10/AR/EYA2/ICAM1/SCG2/YAP1/HGF/TCF7L2/ZMYND11/ACVR1/CTTN/LMNA/CFLAR/ITGAV/IL1B	19
BP	GO:0061136	regulation of proteasomal protein catabolic process	30/2112	183/18670	0.02364	0.09424	0.06809	LAMP3/CLU/NFE2L1/CBFA2T3/PLK1/PSME1/GABARAPL2/CHFR/BAG2/RHBDF1/EDEM1/PLK2/VCP/HSP90AB1/HFE/PINK1/RNF19B/UBE2J1/CEBPA/DVL1/BAG5/EDEM2/ALAD/WAC/PBK/USP7/CAMLG/AURKA/RNF14/UBE2G2	30
BP	GO:0042743	hydrogen peroxide metabolic process	12/2112	57/18670	0.02381	0.09473	0.06844	RAC2/HBB/EGFR/SOD1/GPX3/HBD/PRDX6/PINK1/MAOB/HP/CYBA/CAT	12
BP	GO:0071398	cellular response to fatty acid	12/2112	57/18670	0.02381	0.09473	0.06844	PID1/SFRP1/AKR1C3/ID3/CCNB1/OR51E2/PTGFR/PTGER4/SMARCD1/P2RY6/PDK4/P2RY4	12
BP	GO:1901799	negative regulation of proteasomal protein catabolic process	12/2112	57/18670	0.02381	0.09473	0.06844	LAMP3/GABARAPL2/HSP90AB1/HFE/UBE2J1/BAG5/ALAD/WAC/PBK/USP7/CAMLG/UBE2G2	12
BP	GO:0050796	regulation of insulin secretion	29/2112	176/18670	0.0242	0.09622	0.06952	CCL5/SFRP1/SRI/OXCT1/PPP3CA/TCIRG1/JAK2/KLF7/TM7SF3/MPC2/TCF7L2/PER2/LRP5/EFNA5/PTPN11/RBP4/ARNTL/SLC25A4/LEP/SSTR5/IFNG/STX4/CD38/SYBU/ENSA/SLC25A5/HADH/IL1B/GPR27	29
BP	GO:0071236	cellular response to antibiotic	25/2112	147/18670	0.02437	0.09685	0.06998	PLEKHA1/TNFAIP3/CLU/NQO1/AXL/SIGMAR1/PDGFD/SPHK1/CDK1/HGF/EZH2/ID3/MAPK13/FOXO1/NET1/EFNA5/ECT2/TIMELESS/CCL7/SPI1/PINK1/IL6/FOXO3/TP53/ACTR2	25
BP	GO:0071103	DNA conformation change	49/2112	327/18670	0.02452	0.09738	0.07036	NAP1L2/NAP1L3/SOX9/PURA/CETN2/NUSAP1/CHD1/NCAPD2/CDC45/NCAPH/BLM/SRPK1/SMARCA1/HJURP/NCAPG/TPR/CDK1/TSPYL2/MCM5/RFC3/MCPH1/TOP2A/GINS1/ATRX/NAV2/MCM2/CCNB1/ASF1B/DDX1/CHD4/PARP1/KAT6B/ACTR8/NIPBL/PAF1/HELLS/RSF1/CHAF1B/MCM4/CUL4B/ERCC6L/HMGA1/CHD9/SMC4/CENPM/SMCHD1/TP53/HP1BP3/GTF2H5	49
BP	GO:0038095	Fc-epsilon receptor signaling pathway	28/2112	169/18670	0.02475	0.0981	0.07088	ITK/PSMB9/PIK3R1/PSMB8/PRKCQ/PSMB10/LAT/PPP3CA/MS4A2/SKP1/LCP2/MALT1/PSME1/PLCG2/NFKB1/VAV1/IGLC1/IGLV1-44/PIK3CA/PAK1/SYK/TEC/IKBKG/BTK/FER/GAB2/LYN/VAV3	28
BP	GO:0035023	regulation of Rho protein signal transduction	24/2112	140/18670	0.02475	0.0981	0.07088	ARHGDIB/ARHGEF18/LPAR1/RASIP1/KANK2/ARHGEF9/ARHGEF26/ITSN1/DLC1/GPR18/ARHGEF3/ARHGEF10/ARHGEF12/NET1/VAV1/TNFAIP1/GPR65/MYOC/ECT2/KANK1/AKAP13/GPR4/VAV3/SCAI	24
BP	GO:0042737	drug catabolic process	24/2112	140/18670	0.02475	0.0981	0.07088	AMPD3/FAH/NT5E/OXCT1/HBB/PCBD1/ADA/ACAT1/PCK1/MAOA/GPX3/HPD/IDUA/NAGK/HBD/CYP4B1/PRDX6/BDH1/MAOB/HP/OVGP1/CAT/AASS/CTSH	24
BP	GO:0045445	myoblast differentiation	16/2112	84/18670	0.02499	0.09893	0.07148	CXCL9/BMP4/IGF1/SOX9/CDON/CXCL10/TCF7L2/ID3/PITX1/NOTCH1/ZFP36L1/DDIT3/RB1/IL18/KCNAB1/CCL17	16
BP	GO:0050818	regulation of coagulation	16/2112	84/18670	0.02499	0.09893	0.07148	PRKCQ/CD36/PDPN/PROS1/PROCR/PLEK/VKORC1/PLAT/CD9/SYK/TEC/PRKG1/TFPI/LYN/SH2B3/GP1BA	16
BP	GO:0042770	signal transduction in response to DNA damage	23/2112	133/18670	0.02508	0.09912	0.07162	TFDP2/DTL/BATF/CD74/BID/PLK1/CDC14B/E2F8/CDK1/PMAIP1/ATRX/PLK2/CCNB1/SMYD2/FOXO3/CEP63/HIPK2/PRMT1/PCBP4/USP10/TP53/AURKA/PML	23
BP	GO:0021545	cranial nerve development	11/2112	51/18670	0.02517	0.09912	0.07162	GLI3/SEMA3A/LPAR1/TCIRG1/SIX1/SLC1A3/RPL24/EPHB1/SEMA3F/NAV2/TFAP2A	11
BP	GO:0030834	regulation of actin filament depolymerization	11/2112	51/18670	0.02517	0.09912	0.07162	ADD3/TMOD1/PLEK/DSTN/LMOD1/CFL1/CAPZA1/VILL/WDR1/SPTBN1/GSN	11
BP	GO:0045668	negative regulation of osteoblast differentiation	11/2112	51/18670	0.02517	0.09912	0.07162	SFRP1/IGFBP5/SEMA4D/SKI/HDAC4/TWSG1/ID3/LRP5/SMAD3/NOTCH1/TOB1	11
BP	GO:0048146	positive regulation of fibroblast proliferation	11/2112	51/18670	0.02517	0.09912	0.07162	IGF1/DDR2/BTC/CD74/PDGFD/NDUFS4/EGFR/SPHK1/CCNA2/CCNB1/PML	11
BP	GO:0006907	pinocytosis	6/2112	21/18670	0.02524	0.09912	0.07162	AXL/EHD4/SNX5/DOCK2/MAPKAPK2/NR1H3	6
BP	GO:0010829	negative regulation of glucose transmembrane transport	6/2112	21/18670	0.02524	0.09912	0.07162	ENPP1/PID1/PRKCB/LEP/FABP5/IL1B	6
BP	GO:0035162	embryonic hemopoiesis	6/2112	21/18670	0.02524	0.09912	0.07162	KITLG/GATA2/KMT2A/PBX1/SH2B3/KDR	6
BP	GO:0043153	entrainment of circadian clock by photoperiod	6/2112	21/18670	0.02524	0.09912	0.07162	SIK1/PER2/PPP1CA/PER3/TP53/PML	6
BP	GO:0140058	neuron projection arborization	6/2112	21/18670	0.02524	0.09912	0.07162	SEMA3A/ZNF365/NLGN1/PTN/FZD4/DVL1	6
BP	GO:2000269	regulation of fibroblast apoptotic process	6/2112	21/18670	0.02524	0.09912	0.07162	SFRP1/BID/STK17B/TP63/PIK3CA/TP53	6
BP	GO:2000738	positive regulation of stem cell differentiation	6/2112	21/18670	0.02524	0.09912	0.07162	BMP4/SOX9/LTBP3/FOXC1/SOX5/PTN	6
BP	GO:0032768	regulation of monooxygenase activity	13/2112	64/18670	0.02527	0.09912	0.07162	GCH1/WASL/HTR2B/EGFR/DDAH2/NFKB1/LEP/IFNG/GFI1/GLA/NOD1/NPR3/IL1B	13
BP	GO:0035794	positive regulation of mitochondrial membrane permeability	13/2112	64/18670	0.02527	0.09912	0.07162	TFDP2/GZMB/BID/EYA2/TMEM14A/BAK1/TP63/PMAIP1/SLC25A5/TP53BP2/TP53/BNIP3L/MOAP1	13
BP	GO:0050848	regulation of calcium-mediated signaling	18/2112	98/18670	0.02563	0.1004	0.07256	CD3E/GBP1/IGF1/SRI/TRAT1/ADA/ZAP70/TMEM100/PLEK/PLN/RGN/SYK/P2RY6/PKD2/GSTO1/GSTM2/CAMTA1/HINT1	18
BP	GO:0060191	regulation of lipase activity	18/2112	98/18670	0.02563	0.1004	0.07256	CCL5/ITK/ARL1/NTRK2/LPAR1/HTR2B/EGFR/FGF2/SELE/TXK/HTR2A/ANGPTL4/AGTR1/P2RY6/NR1H3/ANG/LIPC/S1PR4	18
BP	GO:0001938	positive regulation of endothelial cell proliferation	20/2112	112/18670	0.02569	0.1005	0.07265	BMP4/ITGA4/DYSF/PRKD2/HTR2B/SCG2/GATA2/FGF2/THBS4/SP1/PPP1R16B/AGTR1/ARNT/APLNR/AKT3/CYBA/VEGFB/PRKD1/ANG/KDR	20
BP	GO:0031109	microtubule polymerization or depolymerization	20/2112	112/18670	0.02569	0.1005	0.07265	TPPP3/MAPRE2/CRYAB/GOLGA2/CKAP2/KIF18B/FGF13/ZNF207/TUBB4A/KIF2C/MAP7D3/MECP2/TERF1/PAK1/FBXO5/CAMSAP2/MAP1B/CLIP3/TUBG2/CDH5	20
BP	GO:1902750	negative regulation of cell cycle G2/M phase transition	19/2112	105/18670	0.02572	0.1006	0.07268	PSMB9/PSMB8/PSMB10/DTL/SKP1/PLK1/PSME1/CDC14B/BLM/FHL1/CDK1/DONSON/MIIP/AURKB/FBXL7/SYF2/NAE1/AURKA/TOPBP1	19
BP	GO:1903050	regulation of proteolysis involved in cellular protein catabolic process	34/2112	214/18670	0.02579	0.1008	0.07284	LAMP3/CLU/NFE2L1/CBFA2T3/CTSC/PLK1/PSME1/GABARAPL2/CHFR/BAG2/RHBDF1/EDEM1/PLK2/VCP/RGN/HSP90AB1/HFE/PINK1/RNF19B/UBE2J1/CEBPA/HIPK2/DVL1/BAG5/EDEM2/ALAD/WAC/PBK/USP7/CAMLG/AURKA/RNF14/UBE2G2/PML	34
BP	GO:0060491	regulation of cell projection assembly	29/2112	177/18670	0.02592	0.1012	0.07314	DYNC2LI1/RAC2/CCL19/CCR7/AUTS2/PFN2/MAP4/ICAM1/HDAC4/COBL/WASL/DZIP1/SH3YL1/CCL21/WAS/CDC42EP3/PLD1/NLGN1/CEP135/PPP1R16B/KANK1/RHOG/FNBP1L/ATG3/DPYSL3/TGFB3/FER/WASF2/PFN1	29
BP	GO:0007565	female pregnancy	31/2112	192/18670	0.02633	0.1028	0.07425	IGFBP5/IDO1/PTHLH/ARHGDIB/EMP2/AR/PAM/STS/LGALS9/MAGED2/AKR1B1/RECK/PTN/SOD1/PAPPA/CTSB/LEP/PSG11/PRL/FOSL1/CLIC5/HFE/TGFB3/CD38/LDOC1/FBLN1/ENDOU/IGFBP2/OVGP1/COL16A1/IL1B	31
BP	GO:0043433	negative regulation of DNA-binding transcription factor activity	28/2112	170/18670	0.02654	0.1035	0.07479	TRAF3/AIM2/XCL1/TNFAIP3/SRI/PIM1/CD200/NFKBIE/HDAC4/DAP/ADORA3/SIK1/TCF7L2/EZH2/ID3/NFKBIA/TRIM21/GFI1/TNFRSF4/FZD6/ANXA4/DDIT3/RB1/PKD2/CAT/USP7/MED13/NLRP3	28
BP	GO:0044706	multi-multicellular organism process	35/2112	222/18670	0.02661	0.1037	0.07496	IGFBP5/IDO1/PTHLH/ARHGDIB/EMP2/AR/PAM/STS/LGALS9/MAGED2/AKR1B1/RECK/TAC1/PTN/SOD1/PAPPA/PLA2G4C/CTSB/ARNTL/LEP/PSG11/PTGFR/PRL/FOSL1/CLIC5/HFE/TGFB3/CD38/LDOC1/FBLN1/ENDOU/IGFBP2/OVGP1/COL16A1/IL1B	35
BP	GO:0006631	fatty acid metabolic process	56/2112	383/18670	0.02665	0.1038	0.07501	LTC4S/PLP1/ALDH3A2/AKR1C3/ACADVL/NFE2L1/CD74/ACOX2/PAM/SGPL1/CD36/ECHDC2/ERLIN1/FA2H/ACAT1/PCK1/PER2/HPGDS/ETFB/ACACB/PLA2G4C/GPX4/PCCA/HSD17B12/LIPG/LEP/BDH2/RGN/ECI2/ADIPOQ/ERLIN2/FABP5/PDK4/ECI1/AOAH/PTGS1/ELOVL4/NR1H3/SLC27A5/ACADL/ELOVL2/NAAA/HADH/GSTM2/ACSM5/ECHS1/ACSM3/LIPC/PRKAB1/ACSL5/IL1B/EPHX2/ALOX5/ALDH5A1/ELOVL5/HADHA	56
BP	GO:0006949	syncytium formation	12/2112	58/18670	0.02703	0.1052	0.07604	CXCL9/PLEKHO1/CDON/IL4R/CXCL10/SH3PXD2A/CD53/CD9/CD81/CFLAR/ERCC1/SBNO2	12
BP	GO:0008589	regulation of smoothened signaling pathway	15/2112	78/18670	0.02714	0.1053	0.07607	ENPP1/GAS1/CD3E/SFRP1/ZIC1/DLG5/GLI3/SHOX2/CREBBP/TCTN1/FGF9/TULP3/MEGF8/RB1/RFX4	15
BP	GO:0006766	vitamin metabolic process	23/2112	134/18670	0.02715	0.1053	0.07607	ENPP1/KYNU/AKR1C3/CYB5R3/MTHFD2/PC/MCCC1/VKORC1/NFKB1/SLC2A3/PCCA/IFNG/KMO/RGN/GFI1/CD320/CTRB2/SLC23A2/GSTO1/LMBRD1/SLC5A6/TKTL1/IL1B	23
BP	GO:0009649	entrainment of circadian clock	7/2112	27/18670	0.02717	0.1053	0.07607	SIK1/PER2/PPP1CA/PHLPP1/PER3/TP53/PML	7
BP	GO:0009651	response to salt stress	7/2112	27/18670	0.02717	0.1053	0.07607	AKR1B1/MICU1/ZFP36L1/KMO/HSP90AB1/SLC25A23/TP53	7
BP	GO:0046885	regulation of hormone biosynthetic process	7/2112	27/18670	0.02717	0.1053	0.07607	AKR1C3/NFKB1/IFNG/ARNT/GFI1/DKK3/IL1B	7
BP	GO:0031062	positive regulation of histone methylation	9/2112	39/18670	0.02727	0.1053	0.07607	AUTS2/KMT2A/DNMT1/BRD4/MECP2/MTF2/PAF1/JARID2/LMNA	9
BP	GO:0032506	cytokinetic process	9/2112	39/18670	0.02727	0.1053	0.07607	CEP55/KIF20A/RACGAP1/ECT2/CHMP2B/AURKB/KIF20B/CHMP1B/KIF23	9
BP	GO:0045911	positive regulation of DNA recombination	9/2112	39/18670	0.02727	0.1053	0.07607	PTPRC/CD40/TFRC/UBE2B/WAS/TBX21/TIMELESS/PARP1/ACTR2	9
BP	GO:2001234	negative regulation of apoptotic signaling pathway	36/2112	230/18670	0.02739	0.1053	0.07607	TNFAIP3/BMP4/IGF1/CLU/EYA4/BCL2A1/CD74/BID/TNFSF10/AR/EYA2/ICAM1/ACKR3/TMEM14A/SCG2/YAP1/HGF/TCF7L2/CX3CR1/NDUFA13/BCL2L2/ZMYND11/HIGD1A/ACVR1/HSPB1/CTTN/PINK1/IVNS1ABP/LMNA/RB1/SLC25A5/BAG5/NLE1/CFLAR/ITGAV/IL1B	36
BP	GO:0043010	camera-type eye development	47/2112	314/18670	0.02763	0.1053	0.07607	MAB21L2/BMP4/BCL11B/LRP6/CDKN1C/WNT5B/MYH10/TMEM231/SOX9/TMOD1/GLI3/NTRK2/TSKU/FOXC1/SKI/INHBA/CDON/MEIS1/TCIRG1/LIMK2/CRYAB/TWSG1/EGFR/COL8A2/RPL24/COL8A1/SMARCD3/BAK1/EPHB1/PTN/LRP5/EFEMP1/FZD4/SMAD3/RBP4/IRX5/TFAP2A/TULP3/ZHX2/HIPK2/DIO3/MERTK/ROM1/ABI2/NPHP4/CRYGB/AHI1	47
BP	GO:0002756	MyD88-independent toll-like receptor signaling pathway	8/2112	33/18670	0.02766	0.1053	0.07607	TRAF3/BIRC3/IRF7/UBE2D1/IKBKG/TNIP3/RAB11FIP2/TLR6	8
BP	GO:0051204	protein insertion into mitochondrial membrane	8/2112	33/18670	0.02766	0.1053	0.07607	TFDP2/GZMB/BID/TP63/PMAIP1/TP53BP2/TP53/MOAP1	8
BP	GO:1901890	positive regulation of cell junction assembly	8/2112	33/18670	0.02766	0.1053	0.07607	SFRP1/ITGB1BP1/SMAD3/MYOC/PPM1F/KDR/COL16A1/NPHP4	8
BP	GO:0006957	complement activation, alternative pathway	5/2112	16/18670	0.02767	0.1053	0.07607	CFP/CR1/CFD/C7/CFB	5
BP	GO:0010934	macrophage cytokine production	5/2112	16/18670	0.02767	0.1053	0.07607	CD74/HLA-G/CD36/TGFB3/LILRB1	5
BP	GO:0030214	hyaluronan catabolic process	5/2112	16/18670	0.02767	0.1053	0.07607	HMMR/FGF2/LYVE1/HYAL1/STAB2	5
BP	GO:0030889	negative regulation of B cell proliferation	5/2112	16/18670	0.02767	0.1053	0.07607	CTLA4/MNDA/BTK/INPP5D/LYN	5
BP	GO:0032354	response to follicle-stimulating hormone	5/2112	16/18670	0.02767	0.1053	0.07607	INHBA/TGFBR3/PAPPA/EFNA5/NOTCH1	5
BP	GO:0033033	negative regulation of myeloid cell apoptotic process	5/2112	16/18670	0.02767	0.1053	0.07607	CCL5/KITLG/CCR5/NOD2/IRF7	5
BP	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation	5/2112	16/18670	0.02767	0.1053	0.07607	WASL/WAS/GMFG/AP1AR/ABI2	5
BP	GO:0035970	peptidyl-threonine dephosphorylation	5/2112	16/18670	0.02767	0.1053	0.07607	PPP2CA/DUSP5/PPP2CB/PPP1CA/PPM1F	5
BP	GO:0042033	chemokine biosynthetic process	5/2112	16/18670	0.02767	0.1053	0.07607	CD74/IFNG/IL6/IL18/IL1B	5
BP	GO:0043174	nucleoside salvage	5/2112	16/18670	0.02767	0.1053	0.07607	TYMP/UPP1/ADK/TK2/TK1	5
BP	GO:0044065	regulation of respiratory system process	5/2112	16/18670	0.02767	0.1053	0.07607	FTO/PBX3/NLGN1/ATP1A2/MECP2	5
BP	GO:0050655	dermatan sulfate proteoglycan metabolic process	5/2112	16/18670	0.02767	0.1053	0.07607	DCN/BGN/CSPG4/VCAN/IDUA	5
BP	GO:0050755	chemokine metabolic process	5/2112	16/18670	0.02767	0.1053	0.07607	CD74/IFNG/IL6/IL18/IL1B	5
BP	GO:0055012	ventricular cardiac muscle cell differentiation	5/2112	16/18670	0.02767	0.1053	0.07607	MYH10/CDK1/CCNB1/HEY2/LMNA	5
BP	GO:0061548	ganglion development	5/2112	16/18670	0.02767	0.1053	0.07607	SEMA3A/SIX1/UNC5C/SEMA3F/TULP3	5
BP	GO:0070293	renal absorption	5/2112	16/18670	0.02767	0.1053	0.07607	AKR1C3/HBB/MAGED2/ADIPOQ/GSN	5
BP	GO:0072109	glomerular mesangium development	5/2112	16/18670	0.02767	0.1053	0.07607	BMP4/PDGFD/NOTCH1/CFLAR/GPR4	5
BP	GO:0030856	regulation of epithelial cell differentiation	26/2112	156/18670	0.02774	0.1053	0.07607	BMP4/CDKN1C/PRKCH/STAT1/SOX9/FOXC1/CTSL/YAP1/KLF7/TMEM100/EZH2/TP63/NOTCH1/ARNTL/ZFP36L1/IFNG/HEY2/ADIPOQ/CCND1/WWTR1/FAT4/APOLD1/IL1B/CDH5/MYCL/AHI1	26
BP	GO:0003014	renal system process	21/2112	120/18670	0.0278	0.1053	0.07607	BMP4/BTC/AKR1C3/EMP2/XPNPEP3/HBB/SULF1/MAGED2/AKR1B1/TAC1/SNX5/CORO2B/AGTR1/OR51E2/ADIPOQ/EDNRB/CYBA/REN/NPR3/RAB11FIP2/GSN	21
BP	GO:0003174	mitral valve development	4/2112	11/18670	0.02803	0.1053	0.07607	BMPR1A/DCHS1/NOTCH1/ACVR1	4
BP	GO:0008655	pyrimidine-containing compound salvage	4/2112	11/18670	0.02803	0.1053	0.07607	TYMP/UPP1/TK2/TK1	4
BP	GO:0019042	viral latency	4/2112	11/18670	0.02803	0.1053	0.07607	NUCKS1/IRF7/HMGA1/PSIP1	4
BP	GO:0032060	bleb assembly	4/2112	11/18670	0.02803	0.1053	0.07607	LPAR1/EMP2/PMP22/MYLK	4
BP	GO:0032351	negative regulation of hormone metabolic process	4/2112	11/18670	0.02803	0.1053	0.07607	AKR1C3/NFKB1/GFI1/DKK3	4
BP	GO:0032494	response to peptidoglycan	4/2112	11/18670	0.02803	0.1053	0.07607	NOD2/RIPK2/IL6/NLRP3	4
BP	GO:0033089	positive regulation of T cell differentiation in thymus	4/2112	11/18670	0.02803	0.1053	0.07607	RASGRP1/IL7R/ADAM8/ADA	4
BP	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway	4/2112	11/18670	0.02803	0.1053	0.07607	AR/YAP1/PAK1/PARP1	4
BP	GO:0033327	Leydig cell differentiation	4/2112	11/18670	0.02803	0.1053	0.07607	PLEKHA1/AR/SGPL1/CCND1	4
BP	GO:0035457	cellular response to interferon-alpha	4/2112	11/18670	0.02803	0.1053	0.07607	AXL/TPR/IFIT3/IFIT2	4
BP	GO:0035739	CD4-positive, alpha-beta T cell proliferation	4/2112	11/18670	0.02803	0.1053	0.07607	XCL1/LGALS9/TWSG1/CD81	4
BP	GO:0042023	DNA endoreduplication	4/2112	11/18670	0.02803	0.1053	0.07607	E2F8/STAG2/ZPR1/FBXO5	4
BP	GO:0043097	pyrimidine nucleoside salvage	4/2112	11/18670	0.02803	0.1053	0.07607	TYMP/UPP1/TK2/TK1	4
BP	GO:0045628	regulation of T-helper 2 cell differentiation	4/2112	11/18670	0.02803	0.1053	0.07607	IL4R/CD86/IL18/NLRP3	4
BP	GO:0046007	negative regulation of activated T cell proliferation	4/2112	11/18670	0.02803	0.1053	0.07607	LGALS9/BTN2A2/PDCD1LG2/LRRC32	4
BP	GO:0046439	L-cysteine metabolic process	4/2112	11/18670	0.02803	0.1053	0.07607	CDO1/CBS/AHCYL1/AHCYL2	4
BP	GO:0055091	phospholipid homeostasis	4/2112	11/18670	0.02803	0.1053	0.07607	ABCG1/LIPG/CETP/RCN3	4
BP	GO:0060272	embryonic skeletal joint morphogenesis	4/2112	11/18670	0.02803	0.1053	0.07607	BMP4/SHOX2/HYAL1/HOXA11	4
BP	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity	4/2112	11/18670	0.02803	0.1053	0.07607	SRI/PKD2/GSTO1/GSTM2	4
BP	GO:0060767	epithelial cell proliferation involved in prostate gland development	4/2112	11/18670	0.02803	0.1053	0.07607	SOX9/AR/NOTCH1/EAF2	4
BP	GO:0060837	blood vessel endothelial cell differentiation	4/2112	11/18670	0.02803	0.1053	0.07607	TMEM100/NOTCH1/HEY2/HEY1	4
BP	GO:0061314	Notch signaling involved in heart development	4/2112	11/18670	0.02803	0.1053	0.07607	GALNT11/NOTCH1/HEY2/HEY1	4
BP	GO:0072683	T cell extravasation	4/2112	11/18670	0.02803	0.1053	0.07607	CCR2/IL27RA/ICAM1/CCL2	4
BP	GO:1901201	regulation of extracellular matrix assembly	4/2112	11/18670	0.02803	0.1053	0.07607	SOX9/ANTXR1/SMAD3/NOTCH1	4
BP	GO:2000561	regulation of CD4-positive, alpha-beta T cell proliferation	4/2112	11/18670	0.02803	0.1053	0.07607	XCL1/LGALS9/TWSG1/CD81	4
BP	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	4/2112	11/18670	0.02803	0.1053	0.07607	LGALS9/JAK2/SMAD3/GSN	4
BP	GO:0003300	cardiac muscle hypertrophy	19/2112	106/18670	0.02813	0.1056	0.0763	IGF1/TNFRSF1B/PPP3CA/HDAC4/HTR2B/EZH2/SORBS2/PDLIM5/FOXO1/SMAD3/NOTCH1/LEP/IL6ST/HEY2/PAK1/PARP1/AKAP13/JARID2/LMNA	19
BP	GO:0018105	peptidyl-serine phosphorylation	45/2112	299/18670	0.02817	0.1057	0.07635	PRKCH/PRKCQ/NTRK2/VRK2/PRKCB/ANGPT1/HCLS1/PFN2/VRK1/PLK1/PRKD2/RIPK2/EGFR/STK32B/MAP4K1/CDK1/BAK1/HGF/MAPK13/RPS6KA4/PLK2/CDC7/IFNG/CCNB1/PIK3CA/PPM1F/HSP90AB1/PAK1/SYK/PINK1/AKT3/MAPKAPK2/MARK1/IL6/TTK/PRKG1/NLK/AURKB/PRKD1/HIPK2/AURKA/IFNA1/DCLK1/PRKG2/GPD1L	45
BP	GO:0090276	regulation of peptide hormone secretion	33/2112	208/18670	0.02824	0.1059	0.07651	CCL5/SFRP1/SRI/OXCT1/PPP3CA/TCIRG1/JAK2/ITSN1/EGFR/KLF7/TM7SF3/PASK/MPC2/TCF7L2/PER2/LRP5/EFNA5/PTPN11/RBP4/ARNTL/SLC25A4/LEP/SSTR5/IFNG/STX4/HFE/CD38/SYBU/ENSA/SLC25A5/HADH/IL1B/GPR27	33
BP	GO:0031331	positive regulation of cellular catabolic process	53/2112	361/18670	0.02835	0.1062	0.07677	FTO/TNFAIP3/IGF1/CLU/TNFRSF1B/ZBTB20/CBFA2T3/ADAM8/CTSC/PLK1/PIP4K2B/RIPK2/CHFR/DCN/BAG2/HTR2A/TRIM21/FOXO1/EDEM1/PLK2/VCP/ZFP36L1/IFNG/ARNT/TOB1/RGN/DACT1/IKBKG/TRIM22/PINK1/IL6/RNF19B/PIP4K2A/FOXO3/PRKD1/SESN1/NOD1/EPM2A/CEBPA/KDR/DVL1/CD81/EDEM2/ZC3HAV1/ZFP36L2/PRR5L/FYCO1/WAC/BNIP3L/PIM2/AURKA/RNF14/IL1B	53
BP	GO:0051148	negative regulation of muscle cell differentiation	13/2112	65/18670	0.02842	0.1064	0.0769	HDAC4/CXCL10/EZH2/DNMT1/CEACAM5/BHLHE41/FZD7/NOTCH1/MECP2/HEY2/PAK1/FGF9/CFLAR	13
BP	GO:0006998	nuclear envelope organization	11/2112	52/18670	0.02877	0.1075	0.0777	TMEM43/PPP2CA/PRKCB/CCNB2/VRK1/PLK1/NUP93/CDK1/TOR1AIP1/CCNB1/LMNA	11
BP	GO:0072132	mesenchyme morphogenesis	11/2112	52/18670	0.02877	0.1075	0.0777	SOX9/FOXC1/BMPR1A/TMEM100/DCHS1/LEF1/SMAD3/NOTCH1/HEY2/ACVR1/HEY1	11
BP	GO:0099518	vesicle cytoskeletal trafficking	11/2112	52/18670	0.02877	0.1075	0.0777	RASGRP1/TRAK2/WASL/KIF3B/DYNC1I1/FNBP1L/MYO1C/SYBU/FYCO1/KIF1B/KIF23	11
BP	GO:0038127	ERBB signaling pathway	24/2112	142/18670	0.02884	0.1077	0.07785	CPNE3/PIK3R1/BTC/PLCE1/RHBDF2/SOX9/PTPN2/EGFR/GPRC5A/HBEGF/ERBB2/ZGPAT/RHBDF1/EFEMP1/SNX5/PTPN11/MYOC/KIF16B/PIK3CA/FER/NCF1/SH3TC2/MVP/CAMLG	24
BP	GO:0032272	negative regulation of protein polymerization	14/2112	72/18670	0.02943	0.1097	0.07924	ADD3/TMOD1/PFN2/TMSB10/TUBB4A/KANK1/LMOD1/CAPZA1/VILL/CLIP3/PFN1/SPTBN1/GSN/CDH5	14
BP	GO:0035019	somatic stem cell population maintenance	14/2112	72/18670	0.02943	0.1097	0.07924	SFRP1/SOX9/SKI/SIX2/YAP1/GATA2/FGF2/SOX2/TP63/PBX1/POLR2L/SPI1/ZHX2/ZFP36L2	14
BP	GO:0051881	regulation of mitochondrial membrane potential	14/2112	72/18670	0.02943	0.1097	0.07924	PID1/BID/DCN/BAK1/SLC25A36/SOD1/ARL6IP5/PMAIP1/MYOC/VCP/PARP1/PINK1/KDR/BNIP3L	14
BP	GO:1903051	negative regulation of proteolysis involved in cellular protein catabolic process	14/2112	72/18670	0.02943	0.1097	0.07924	LAMP3/GABARAPL2/HSP90AB1/HFE/UBE2J1/HIPK2/BAG5/ALAD/WAC/PBK/USP7/CAMLG/UBE2G2/PML	14
BP	GO:0008361	regulation of cell size	29/2112	179/18670	0.02963	0.1104	0.07975	SEMA4A/IL7R/SEMA4D/SEMA3A/DEPTOR/FGF13/TRPV2/PLEK/RYK/PTPRS/SEMA3F/EFNA5/VAV1/GDI1/SLC12A2/HSP90AB1/PAK1/SLC12A8/CTTN/AKT3/MAP1B/ARHGAP4/MEGF8/DPYSL2/SEMA4F/SEMA3E/SLC12A7/SEMA6B/VAV3	29
BP	GO:0001654	eye development	53/2112	362/18670	0.02968	0.1105	0.07983	MAB21L2/BMP4/BCL11B/LRP6/CDKN1C/WNT5B/SCO2/MYH10/TMEM231/SOX9/TMOD1/GLI3/NTRK2/TSKU/FOXC1/SKI/INHBA/CDON/MEIS1/TCIRG1/LIMK2/CRYAB/TWSG1/MEIS2/EGFR/COL8A2/RPL24/COL8A1/SMARCD3/BAK1/SOX2/EPHB1/PTN/LRP5/EFEMP1/FZD4/SMAD3/RBP4/IRX5/CHRDL1/TFAP2A/FGF9/NIPBL/TULP3/ZHX2/HIPK2/DIO3/MERTK/ROM1/ABI2/NPHP4/CRYGB/AHI1	53
BP	GO:0030509	BMP signaling pathway	26/2112	157/18670	0.02979	0.1108	0.08006	SFRP1/GDF5/BMP4/SKI/HTRA1/SULF1/BMPR1A/COMP/TWSG1/TGFBR3/TMEM100/NEO1/LEF1/UBE2D1/NOTCH1/NBL1/TOB1/CHRDL1/ACVR1/HFE/MEGF8/FST/HIPK2/FSTL3/ZNF8/CDH5	26
BP	GO:0021675	nerve development	15/2112	79/18670	0.03011	0.1118	0.0808	ITGA4/GLI3/SEMA3A/LPAR1/TCIRG1/SULF1/SIX1/DAG1/SLC1A3/RPL24/EPHB1/AFG3L2/SEMA3F/NAV2/TFAP2A	15
BP	GO:0030193	regulation of blood coagulation	15/2112	79/18670	0.03011	0.1118	0.0808	PRKCQ/CD36/PDPN/PROS1/PLEK/VKORC1/PLAT/CD9/SYK/TEC/PRKG1/TFPI/LYN/SH2B3/GP1BA	15
BP	GO:1900034	regulation of cellular response to heat	15/2112	79/18670	0.03011	0.1118	0.0808	IER5/CRYAB/NUP93/CREBBP/TPR/BAG2/NUP160/HSP90AB1/DNAJC7/MAPKAPK2/HSPA1L/NUP88/BAG5/NUP50/DNAJC2	15
BP	GO:0001704	formation of primary germ layer	21/2112	121/18670	0.03018	0.112	0.08089	BMP4/ITGA4/FOXC1/INHBA/ITGB2/EYA2/BMPR1A/WLS/SIX2/TWSG1/COL8A1/SOX2/LEF1/SMAD3/FZD7/KIF16B/ACVR1/PAF1/EXT2/HOXA11/ITGAV	21
BP	GO:0015980	energy derivation by oxidation of organic compounds	43/2112	285/18670	0.03018	0.112	0.08089	ENPP1/PID1/IGF1/PPP1R3C/NDUFC1/ACADVL/BID/NDUFS2/CBFA2T3/FASTKD5/NDUFS4/PASK/IDH2/PHKB/CDK1/SLC25A22/PER2/ETFB/NDUFA13/SUCLA2/KL/VCP/GFPT1/LEP/IL6ST/IFNG/CCNB1/PPP1CA/PIK3CA/MECP2/SORBS1/SLC25A23/PINK1/NDUFA9/MDH1/UGP2/SDHA/NDUFB6/CAT/GFPT2/TP53/NDUFA4/ALDH5A1	43
BP	GO:0002437	inflammatory response to antigenic stimulus	10/2112	46/18670	0.03039	0.1124	0.08121	RASGRP1/CCR7/ICAM1/HLA-E/CD6/PNMA1/NOTCH1/BTK/CD81/IL2RA	10
BP	GO:0022602	ovulation cycle process	10/2112	46/18670	0.03039	0.1124	0.08121	PLEKHA1/INHBA/PAM/SGPL1/FZD4/LEP/TGFB3/FOXO3/NRIP1/PTX3	10
BP	GO:0032480	negative regulation of type I interferon production	10/2112	46/18670	0.03039	0.1124	0.08121	RELB/TNFAIP3/UBE2L6/NMI/IFIH1/DDX58/PTPRS/HERC5/ISG15/LILRB1	10
BP	GO:0071675	regulation of mononuclear cell migration	10/2112	46/18670	0.03039	0.1124	0.08121	CCL5/SLAMF8/CCR2/PDGFD/CXCL10/CCR1/NBL1/FPR2/LYN/PLA2G7	10
BP	GO:0021543	pallium development	28/2112	172/18670	0.03041	0.1124	0.08121	LRP6/TACC3/GNG12/ASPM/BCL2A1/GLI3/NTRK2/SEMA3A/CDON/ANXA3/EGFR/FGF13/TACC1/EZH2/CDH2/MCPH1/PTPRS/LEF1/DIXDC1/FEZ1/TACC2/PAX5/FAT4/EMX2/POU3F3/EZH1/FEZF2/MBOAT7	28
BP	GO:0051262	protein tetramerization	28/2112	172/18670	0.03041	0.1124	0.08121	CCL5/CD247/CD74/CBY1/RRM2/PCBD1/GOLGA2/CUTC/CPSF6/NLGN1/TP63/ACACB/KCNJ2/MS4A1/GPX3/VASP/MAT1A/RYR3/ACADL/PKD2/CAT/AASS/KRT10/TK1/TP53/TRPM6/ALDH5A1/ST13	28
BP	GO:0006898	receptor-mediated endocytosis	47/2112	316/18670	0.03048	0.1126	0.08134	LRP6/CLU/MICALL1/APOL1/CCL19/ITGA4/LRP3/ANGPT1/TBC1D5/GAK/HBB/ITGB2/USP46/ACKR3/CD36/WASL/HTR2B/DNM1/TFRC/CXCL8/SELE/PLCG2/CCL21/MAGI2/SCARF1/FCGR1B/LRPAP1/CD9/COLEC12/IGLC1/IGLV1-44/CD163/FNBP1L/SYK/HFE/CTTN/SCARB2/LRP1B/HP/FPR2/CD81/ATXN2/MTMR2/SH3GL3/STAB2/LILRB1/AHI1	47
BP	GO:1903363	negative regulation of cellular protein catabolic process	16/2112	86/18670	0.03054	0.1127	0.08146	LAMP3/NELL1/GABARAPL2/HSP90AB1/HFE/UBE2J1/HIPK2/BAG5/ALAD/WAC/PBK/ATRAID/USP7/CAMLG/UBE2G2/PML	16
BP	GO:0010959	regulation of metal ion transport	57/2112	394/18670	0.03067	0.1131	0.08174	CCL5/CXCL9/XCL1/CORO1A/LILRB2/CXCR4/SRI/CACNA2D1/ANK2/FXYD1/ICAM1/DYSF/FXYD6/NETO2/GEM/CXCL10/PTPN6/SLC31A2/FHL1/TRPV2/PLCG2/SIK1/BAK1/AHCYL1/CCR1/PLN/KCNJ2/TRPC1/HTR2A/CD19/ATP1B1/SCN1B/IL16/IFNG/RGN/ATP1A2/CXCL11/SLC8A1/FGF14/P2RY6/APLNR/VAMP2/HFE/TESC/CYBA/LYN/PKD2/GSTO1/KCNAB1/MYLK/GSTM2/CCL2/SNTA1/CASK/PML/LILRB1/GPD1L	57
BP	GO:0062014	negative regulation of small molecule metabolic process	19/2112	107/18670	0.0307	0.1132	0.08179	PID1/AKR1C3/ACADVL/CBFA2T3/HDAC4/PLEK/SIK1/ERLIN1/SOD1/ACACB/FAM3C/NFKB1/ADIPOQ/ERLIN2/GFI1/PARP1/ACADL/DKK3/TP53	19
BP	GO:1901655	cellular response to ketone	17/2112	93/18670	0.03076	0.1133	0.08189	SFRP1/AKR1C3/AR/ICAM1/AKR1B1/EGFR/MAP4K1/PCK1/FOXO1/EFNA5/PTGFR/PTGER4/P2RY6/FOXO3/RWDD1/CFLAR/P2RY4	17
BP	GO:0045861	negative regulation of proteolysis	53/2112	363/18670	0.03106	0.1143	0.08262	LAMP3/SERPINA1/GAS1/TNFAIP8/BIRC3/TIMP3/SPOCK2/CST7/SERPINA3/SERPINA5/SLPI/PTTG1/SPOCK1/TIMP4/CRYAB/TIMP2/RPS6KA1/GABARAPL2/RECK/PROS1/CR1/UBE2Z/SPINT2/ITIH5/HGF/GLG1/CD27/PLAT/PEBP1/LEF1/TRIM21/SERPINI1/MICAL1/LXN/HSP90AB1/HFE/SERPINB1/APLP2/UBE2J1/TFPI/HIPK2/BAG5/NLE1/CFLAR/SPINK5/ALAD/WAC/PBK/TP53/USP7/CAMLG/UBE2G2/PML	53
BP	GO:0044344	cellular response to fibroblast growth factor stimulus	24/2112	143/18670	0.03107	0.1143	0.08262	CCL5/CXCL13/SFRP1/RBFOX2/FGF18/FGF7/ITGB1BP1/SULF1/PRKD2/FGF2/CXCL8/HYAL1/PTPN11/KL/GTF2F1/KIF16B/ZFP36L1/POLR2L/FGF9/FAT4/SHCBP1/ZFP36L2/CCL2/RAB14	24
BP	GO:0048880	sensory system development	54/2112	371/18670	0.03132	0.1149	0.083	MAB21L2/BMP4/BCL11B/LRP6/CDKN1C/WNT5B/SCO2/MYH10/TMEM231/SOX9/TMOD1/GLI3/NTRK2/TSKU/FOXC1/SEMA3A/SKI/INHBA/CDON/MEIS1/TCIRG1/LIMK2/CRYAB/TWSG1/MEIS2/EGFR/COL8A2/RPL24/COL8A1/SMARCD3/BAK1/SOX2/EPHB1/PTN/LRP5/EFEMP1/FZD4/SMAD3/RBP4/IRX5/CHRDL1/TFAP2A/FGF9/NIPBL/TULP3/ZHX2/HIPK2/DIO3/MERTK/ROM1/ABI2/NPHP4/CRYGB/AHI1	54
BP	GO:0002089	lens morphogenesis in camera-type eye	6/2112	22/18670	0.03147	0.1149	0.083	BMP4/SKI/MEIS1/HIPK2/ABI2/CRYGB	6
BP	GO:0010869	regulation of receptor biosynthetic process	6/2112	22/18670	0.03147	0.1149	0.083	JAK2/IFNG/ADIPOQ/NR1H3/ITGAV/HOXA5	6
BP	GO:0022010	central nervous system myelination	6/2112	22/18670	0.03147	0.1149	0.083	CLU/PLP1/TLR2/ASPA/FA2H/TENM4	6
BP	GO:0032069	regulation of nuclease activity	6/2112	22/18670	0.03147	0.1149	0.083	GZMA/OAS2/OAS1/OASL/TERF1/OAS3	6
BP	GO:0032291	axon ensheathment in central nervous system	6/2112	22/18670	0.03147	0.1149	0.083	CLU/PLP1/TLR2/ASPA/FA2H/TENM4	6
BP	GO:0034643	establishment of mitochondrion localization, microtubule-mediated	6/2112	22/18670	0.03147	0.1149	0.083	UCHL1/TRAK2/FEZ1/MAP1B/SYBU/KIF1B	6
BP	GO:0035024	negative regulation of Rho protein signal transduction	6/2112	22/18670	0.03147	0.1149	0.083	RASIP1/DLC1/TNFAIP1/MYOC/KANK1/SCAI	6
BP	GO:0035929	steroid hormone secretion	6/2112	22/18670	0.03147	0.1149	0.083	INHBA/TAC1/FZD4/PTPN11/AGTR1/REN	6
BP	GO:0045649	regulation of macrophage differentiation	6/2112	22/18670	0.03147	0.1149	0.083	INHBA/PTPN2/HCLS1/GATA2/ADIPOQ/RB1	6
BP	GO:0047497	mitochondrion transport along microtubule	6/2112	22/18670	0.03147	0.1149	0.083	UCHL1/TRAK2/FEZ1/MAP1B/SYBU/KIF1B	6
BP	GO:0071379	cellular response to prostaglandin stimulus	6/2112	22/18670	0.03147	0.1149	0.083	SFRP1/AKR1C3/PTGFR/PTGER4/P2RY6/P2RY4	6
BP	GO:0071404	cellular response to low-density lipoprotein particle stimulus	6/2112	22/18670	0.03147	0.1149	0.083	ITGB2/CD36/NPC1/CD9/SYK/CD81	6
BP	GO:0090312	positive regulation of protein deacetylation	6/2112	22/18670	0.03147	0.1149	0.083	PRKD2/IFNG/NIPBL/PINK1/PRKD1/TP53	6
BP	GO:1905330	regulation of morphogenesis of an epithelium	29/2112	180/18670	0.03164	0.1154	0.08339	PSMB9/SFRP1/BMP4/PSMB8/STAT1/PSMB10/SOX9/FGF7/AR/SULF1/SIX1/SIX2/CXCL10/PSME1/ETV5/HGF/MAGI2/RYK/PLEKHA4/FZD4/FZD7/DACT1/GPC4/ITGAX/FZD6/DVL1/FZD2/PFN1/AHI1	29
BP	GO:0008156	negative regulation of DNA replication	9/2112	40/18670	0.03177	0.1158	0.08369	TTF1/BLM/STAG2/TSPYL2/DONSON/TIMELESS/TERF1/FBXO5/TP53	9
BP	GO:0051785	positive regulation of nuclear division	13/2112	66/18670	0.03185	0.1159	0.08376	IGF1/BTC/NUSAP1/UBE2C/UBE2B/SPHK1/DLGAP5/LRP5/DAZL/NIPBL/RB1/AURKA/IL1B	13
BP	GO:1902108	regulation of mitochondrial membrane permeability involved in apoptotic process	13/2112	66/18670	0.03185	0.1159	0.08376	TFDP2/GZMB/BID/EYA2/TMEM14A/BAK1/TP63/PMAIP1/SLC25A5/TP53BP2/TP53/BNIP3L/MOAP1	13
BP	GO:1905710	positive regulation of membrane permeability	13/2112	66/18670	0.03185	0.1159	0.08376	TFDP2/GZMB/BID/EYA2/TMEM14A/BAK1/TP63/PMAIP1/SLC25A5/TP53BP2/TP53/BNIP3L/MOAP1	13
BP	GO:0043467	regulation of generation of precursor metabolites and energy	26/2112	158/18670	0.03195	0.1162	0.08396	ENPP1/IGF1/ZBTB20/SLC2A6/CBFA2T3/COX7A1/NUP93/HDAC4/PASK/TPR/CDK1/NUP160/HTR2A/VCP/IFNG/ARNT/CCNB1/PPP1CA/PIK3CA/SORBS1/SLC25A23/PINK1/NUP88/NUP50/TP53/COX7A2	26
BP	GO:0046434	organophosphate catabolic process	38/2112	248/18670	0.03219	0.117	0.08455	ENPP1/AMPD3/IGF1/NT5E/ZBTB20/UPP1/SLC2A6/CBFA2T3/NUP93/HDAC4/HK3/ADA/PNPLA6/ALDOC/PDE1A/PLCG2/TPR/ACAT1/NUP160/PLA2G4C/HTR2A/INPP1/LIPG/VCP/IFNG/ARNT/NUDT11/PNP/PRDX6/ABHD6/ENTPD4/NUP88/HINT1/MTMR2/LIPC/NUP50/TP53/GPD1L	38
BP	GO:0009164	nucleoside catabolic process	8/2112	34/18670	0.03269	0.1182	0.08543	TYMP/NT5E/UPP1/APOBEC3G/APOBEC3B/ADA/PNP/ENTPD4	8
BP	GO:0010922	positive regulation of phosphatase activity	8/2112	34/18670	0.03269	0.1182	0.08543	PTPRC/JAK2/PLEK/MAGI2/SMAD3/IFNG/RGN/HSP90AB1	8
BP	GO:0048566	embryonic digestive tract development	8/2112	34/18670	0.03269	0.1182	0.08543	GLI3/SIX2/SHOX2/ADA/CXCL8/TCF7/FGF9/NIPBL	8
BP	GO:0060795	cell fate commitment involved in formation of primary germ layer	8/2112	34/18670	0.03269	0.1182	0.08543	BMP4/EYA2/BMPR1A/SIX2/SOX2/FZD7/PAF1/HOXA11	8
BP	GO:0045661	regulation of myoblast differentiation	11/2112	53/18670	0.03272	0.1182	0.08543	CXCL9/BMP4/SOX9/CDON/CXCL10/ID3/NOTCH1/ZFP36L1/DDIT3/IL18/CCL17	11
BP	GO:0045840	positive regulation of mitotic nuclear division	11/2112	53/18670	0.03272	0.1182	0.08543	IGF1/BTC/NUSAP1/UBE2C/SPHK1/DLGAP5/LRP5/NIPBL/RB1/AURKA/IL1B	11
BP	GO:1903307	positive regulation of regulated secretory pathway	11/2112	53/18670	0.03272	0.1182	0.08543	HLA-F/ITGB2/IL4R/GATA2/FGR/NLGN1/RAB27A/STX4/SYK/STXBP1/GAB2	11
BP	GO:0045685	regulation of glial cell differentiation	14/2112	73/18670	0.03275	0.1182	0.08543	TNFRSF1B/CXCR4/ZNF365/TLR2/DAG1/ASPA/CDK1/PTN/DAAM2/NOTCH1/IL6ST/IL6/TENM4/WDR1	14
BP	GO:0032886	regulation of microtubule-based process	34/2112	218/18670	0.03278	0.1182	0.08543	EPHA3/TACC3/MAPRE2/PLK1/TPX2/BORA/CKAP2/KIF11/FGF13/TPR/ERBB2/MAP9/STAG2/TUBB4A/MCPH1/NEK2/EFNA5/DIXDC1/PLK2/FEZ1/MECP2/TERF1/PAK1/TRIM58/CAMSAP2/CEP85/MAP1B/CHMP2B/CLIP3/CCNF/AURKA/CDH5/CHMP1B/STIL	34
BP	GO:0001773	myeloid dendritic cell activation	7/2112	28/18670	0.0328	0.1182	0.08543	RELB/CD2/SLAMF1/BATF/IRF4/DOCK2/SPI1	7
BP	GO:0034698	response to gonadotropin	7/2112	28/18670	0.0328	0.1182	0.08543	INHBA/ICAM1/TGFBR3/CCNA2/PAPPA/EFNA5/NOTCH1	7
BP	GO:0043501	skeletal muscle adaptation	7/2112	28/18670	0.0328	0.1182	0.08543	IGFBP5/IL15/PPP3CA/GTF2IRD2B/MYOC/GTF2IRD1/CFLAR	7
BP	GO:0060512	prostate gland morphogenesis	7/2112	28/18670	0.0328	0.1182	0.08543	SFRP1/BMP4/SOX9/AR/SULF1/TP63/NOTCH1	7
BP	GO:2000108	positive regulation of leukocyte apoptotic process	7/2112	28/18670	0.0328	0.1182	0.08543	CCL5/IDO1/LGALS9/ADAM8/PIK3CD/LYN/TP53	7
BP	GO:0046660	female sex differentiation	20/2112	115/18670	0.03312	0.1193	0.08622	KITLG/PLEKHA1/SFRP1/FOXC1/INHBA/AXL/ZFPM2/SGPL1/ICAM1/BAK1/TP63/SOD1/FZD4/RBP4/LEP/FOXO3/ANG/MERTK/NRIP1/PTX3	20
BP	GO:2000278	regulation of DNA biosynthetic process	19/2112	108/18670	0.03345	0.1204	0.08702	PRKCQ/PRKD2/FGF2/HGF/KCNK2/NOX4/NEK7/RFC3/NEK2/RGN/TERF1/HSP90AB1/ADIPOQ/PARP4/AURKB/TP53/PARM1/PARN/DNAJC2	19
BP	GO:0045844	positive regulation of striated muscle tissue development	16/2112	87/18670	0.03364	0.1208	0.08727	BMP4/IGF1/PIM1/CDON/ZFPM2/BMPR1A/SHOX2/YAP1/FGF2/TGFBR3/CDK1/NOTCH1/ARNTL/CCNB1/HEY2/FGF9	16
BP	GO:0048477	oogenesis	16/2112	87/18670	0.03364	0.1208	0.08727	IGF1/ASPM/NPR2/CDC25B/PTN/DAZL/CCNB1/FBXO5/REC8/FOXO3/ANG/ERCC1/TRIP13/AURKA/YBX2/PTX3	16
BP	GO:0048636	positive regulation of muscle organ development	16/2112	87/18670	0.03364	0.1208	0.08727	BMP4/IGF1/PIM1/CDON/ZFPM2/BMPR1A/SHOX2/YAP1/FGF2/TGFBR3/CDK1/NOTCH1/ARNTL/CCNB1/HEY2/FGF9	16
BP	GO:0000018	regulation of DNA recombination	18/2112	101/18670	0.03366	0.1208	0.08727	PTPRC/IL27RA/IL7R/ZNF365/CD40/TFRC/UBE2B/BLM/WAS/TBX21/PPP4C/TIMELESS/PARP1/KPNA2/RAD51AP1/THOC1/SMCHD1/ACTR2	18
BP	GO:0002027	regulation of heart rate	18/2112	101/18670	0.03366	0.1208	0.08727	GCH1/SRI/SEMA3A/CACNA2D1/ANK2/ADA/KCNJ5/TAC1/PLN/KCNJ2/SCN1B/IRX5/DSC2/HEY2/SLC8A1/POPDC2/SNTA1/GPD1L	18
BP	GO:0034440	lipid oxidation	18/2112	101/18670	0.03366	0.1208	0.08727	ALDH3A2/ACADVL/ACOX2/ECHDC2/ACAT1/ETFB/ACACB/LEP/BDH2/ECI2/ADIPOQ/PDK4/ECI1/ACADL/HADH/ECHS1/PLA2G7/HADHA	18
BP	GO:0006906	vesicle fusion	17/2112	94/18670	0.03373	0.121	0.08741	TAP1/TAPBP/CORO1A/TAP2/RAB8A/LRMP/DYSF/SPHK1/SAMD9/STX16/VPS16/RAB20/STX4/STXBP1/STX6/VTI1B/VAV3	17
BP	GO:0051188	cofactor biosynthetic process	48/2112	326/18670	0.03394	0.1216	0.08789	IGF1/GCH1/IDO1/ZBTB20/KYNU/NFE2L1/SLC2A6/CBFA2T3/PCBD1/NUP93/HDAC4/HK3/ALDOC/CNDP2/MPC2/IDH2/TPR/ACAT1/NUP160/SOD1/ACACB/HTR2A/MOCS2/HSD17B12/SUCLA2/MAT1A/ALAS1/IFNG/ARNT/BDH2/KMO/RGN/MBIP/PDK4/NDUFA9/MAOB/ELOVL4/MPC1/HMBS/CYBA/HAGH/NUP88/ELOVL2/ALAD/NUP50/TP53/ACSL5/ELOVL5	48
BP	GO:0051893	regulation of focal adhesion assembly	12/2112	60/18670	0.0344	0.1231	0.08897	SFRP1/EPHA3/LIMCH1/ITGB1BP1/DLC1/EFNA5/SMAD3/MYOC/PPM1F/RHOD/KDR/COL16A1	12
BP	GO:0090109	regulation of cell-substrate junction assembly	12/2112	60/18670	0.0344	0.1231	0.08897	SFRP1/EPHA3/LIMCH1/ITGB1BP1/DLC1/EFNA5/SMAD3/MYOC/PPM1F/RHOD/KDR/COL16A1	12
BP	GO:0048588	developmental cell growth	36/2112	234/18670	0.03442	0.1231	0.08897	IGF1/SEMA4A/CXCR4/NDN/SOX9/ITGA4/SEMA4D/SEMA3A/AUTS2/COBL/FGF13/TRPV2/SORBS2/PDLIM5/RYK/PTPRS/SEMA3F/CYFIP2/EFNA5/GDI1/SYT17/HSP90AB1/PAK1/CTTN/AKAP13/MAP1B/ARHGAP4/MEGF8/BCL11A/DPYSL2/SEMA4F/SEMA3E/DVL1/SEMA6B/AURKA/DCLK1	36
BP	GO:0014911	positive regulation of smooth muscle cell migration	10/2112	47/18670	0.03483	0.1243	0.08978	CCL5/IGFBP5/IGF1/LPAR1/PDGFD/HDAC4/NOX4/PAK1/P2RY6/FGF9	10
BP	GO:0030261	chromosome condensation	10/2112	47/18670	0.03483	0.1243	0.08978	NUSAP1/NCAPD2/NCAPH/NCAPG/CDK1/MCPH1/TOP2A/CCNB1/NIPBL/SMC4	10
BP	GO:0048806	genitalia development	10/2112	47/18670	0.03483	0.1243	0.08978	LRP6/AXL/AR/TCF7/BAK1/TP63/PTPN11/RBP4/NIPBL/MERTK	10
BP	GO:0061383	trabecula morphogenesis	10/2112	47/18670	0.03483	0.1243	0.08978	SFRP1/SEMA4D/BMPR1A/TGFBR3/RBP4/NOTCH1/HEY2/HEY1/S1PR1/SBNO2	10
BP	GO:1903580	positive regulation of ATP metabolic process	10/2112	47/18670	0.03483	0.1243	0.08978	PID1/IGF1/ZBTB20/CDK1/HTR2A/VCP/IFNG/ARNT/CCNB1/PINK1	10
BP	GO:0034764	positive regulation of transmembrane transport	32/2112	204/18670	0.03491	0.1245	0.08993	CXCL9/XCL1/PIK3R1/CCR2/IGF1/SRI/CACNA2D1/ANK2/FXYD1/CXCL10/PLCG2/KCNJ2/TRPC1/CD19/ATP1B1/PTPN11/CA2/IFNG/RGN/CXCL11/FGF14/ADIPOQ/P2RY6/APLNR/SORBS1/PINK1/TESC/CLIP3/PKD2/GSTO1/GSTM2/CCL2	32
BP	GO:0009116	nucleoside metabolic process	21/2112	123/18670	0.03538	0.1259	0.09098	AMPD3/TYMP/NT5E/UPP1/ADK/APOBEC3G/APOBEC3B/NME7/ADA/AHCYL1/MACROD1/MOCS2/PNP/MBIP/AHCYL2/ENTPD4/NME4/TK2/TK1/CASK/PRPS2	21
BP	GO:0150063	visual system development	53/2112	366/18670	0.03548	0.1259	0.09098	MAB21L2/BMP4/BCL11B/LRP6/CDKN1C/WNT5B/SCO2/MYH10/TMEM231/SOX9/TMOD1/GLI3/NTRK2/TSKU/FOXC1/SKI/INHBA/CDON/MEIS1/TCIRG1/LIMK2/CRYAB/TWSG1/MEIS2/EGFR/COL8A2/RPL24/COL8A1/SMARCD3/BAK1/SOX2/EPHB1/PTN/LRP5/EFEMP1/FZD4/SMAD3/RBP4/IRX5/CHRDL1/TFAP2A/FGF9/NIPBL/TULP3/ZHX2/HIPK2/DIO3/MERTK/ROM1/ABI2/NPHP4/CRYGB/AHI1	53
BP	GO:0048747	muscle fiber development	13/2112	67/18670	0.03558	0.1259	0.09098	SGCB/BMP4/UCHL1/SKI/PPP3CA/SIX1/DYSF/HDAC4/COMP/SHOX2/AFG3L2/SGCD/MYH11	13
BP	GO:1903391	regulation of adherens junction organization	13/2112	67/18670	0.03558	0.1259	0.09098	SFRP1/EPHA3/LIMCH1/MAPRE2/ITGB1BP1/DLC1/EFNA5/SMAD3/MYOC/PPM1F/RHOD/KDR/COL16A1	13
BP	GO:0010744	positive regulation of macrophage derived foam cell differentiation	5/2112	17/18670	0.03564	0.1259	0.09098	PRKCH/CD36/NFKB1/AGTR1/IL18	5
BP	GO:0017085	response to insecticide	5/2112	17/18670	0.03564	0.1259	0.09098	MAPK13/SCN1B/CCNB1/MAP1B/KIF1B	5
BP	GO:0021783	preganglionic parasympathetic fiber development	5/2112	17/18670	0.03564	0.1259	0.09098	SEMA3A/SIX1/SEMA3F/NAV2/TFAP2A	5
BP	GO:0030540	female genitalia development	5/2112	17/18670	0.03564	0.1259	0.09098	AXL/BAK1/TP63/RBP4/MERTK	5
BP	GO:0043923	positive regulation by host of viral transcription	5/2112	17/18670	0.03564	0.1259	0.09098	NUCKS1/CHD1/CCNT1/SP1/LEF1	5
BP	GO:0048535	lymph node development	5/2112	17/18670	0.03564	0.1259	0.09098	IL15/IL7R/LTB/PDPN/TOX	5
BP	GO:0061323	cell proliferation involved in heart morphogenesis	5/2112	17/18670	0.03564	0.1259	0.09098	BMP4/SOX9/PIM1/SIX1/NOTCH1	5
BP	GO:0072673	lamellipodium morphogenesis	5/2112	17/18670	0.03564	0.1259	0.09098	PLEKHO1/ARPIN/PDPN/KANK1/WASF2	5
BP	GO:0098856	intestinal lipid absorption	5/2112	17/18670	0.03564	0.1259	0.09098	CD36/AKR1C1/LEP/UGCG/SOAT2	5
BP	GO:2000136	regulation of cell proliferation involved in heart morphogenesis	5/2112	17/18670	0.03564	0.1259	0.09098	BMP4/SOX9/PIM1/SIX1/NOTCH1	5
BP	GO:2000811	negative regulation of anoikis	5/2112	17/18670	0.03564	0.1259	0.09098	NTRK2/CEACAM5/NOTCH1/PIK3CA/PDK4	5
BP	GO:2001267	regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	5/2112	17/18670	0.03564	0.1259	0.09098	LGALS9/JAK2/SMAD3/NLE1/GSN	5
BP	GO:0030072	peptide hormone secretion	38/2112	250/18670	0.03586	0.1266	0.0915	CCL5/SFRP1/SRI/OXCT1/PPP3CA/TCIRG1/JAK2/ITSN1/EGFR/KLF7/TM7SF3/PASK/MPC2/CYB5R4/TCF7L2/PER2/LRP5/CPE/EFNA5/PTPN11/RBP4/ARNTL/SLC25A4/LEP/SSTR5/IFNG/STX4/HFE/IL6/CD38/SYBU/ENSA/IL1RN/SLC25A5/HADH/RAB11FIP2/IL1B/GPR27	38
BP	GO:0006913	nucleocytoplasmic transport	50/2112	343/18670	0.03623	0.1279	0.09238	PIK3R1/BMP4/ZIC1/PTPN14/GLI3/PPP3CA/ANGPT1/HCLS1/MX2/MALT1/CD36/NUP93/SIX2/XPO6/IFI27/CPSF6/TPR/BARD1/AHCYL1/TCF7L2/NFKBIA/NUP160/ZPR1/SMAD3/PTPN11/ARNTL/ECT2/LEP/IFNG/THOC2/SYK/FGF9/AKAP13/SNRPB/DDX39A/IPO7/KPNA2/LMNA/FERMT1/NUP88/THOC1/NUP50/TP53/KHDRBS1/HEATR3/THOC6/IL1B/MMP12/PML/XPO4	50
BP	GO:0006081	cellular aldehyde metabolic process	14/2112	74/18670	0.03634	0.128	0.09251	ALDH7A1/ALDH3A2/AKR1C3/ESD/AKR1C1/IDH2/RPIA/PGD/GLO1/ADH5/HAGH/DKK3/TALDO1/AKR7A2	14
BP	GO:0051145	smooth muscle cell differentiation	14/2112	74/18670	0.03634	0.128	0.09251	SGCB/BMP4/SOX9/SIX1/COMP/SMARCD3/DNMT1/NOTCH1/MECP2/HEY2/ACVR1/EDNRB/FGF9/HEY1	14
BP	GO:0086001	cardiac muscle cell action potential	14/2112	74/18670	0.03634	0.128	0.09251	CACNA2D1/ANK2/KCNJ5/FGF13/KCNJ2/ATP1B1/SCN1B/KCNJ8/DSC2/ATP1A2/SLC8A1/GJC1/SNTA1/GPD1L	14
BP	GO:0021915	neural tube development	26/2112	160/18670	0.03663	0.129	0.09319	SFRP1/BMP4/LRP6/GLI3/SKI/COBL/ZNF358/DLC1/SPINT2/TCF7/DCHS1/TCTN1/VASP/NOTCH1/ZFP36L1/DACT1/TULP3/APAF1/FZD6/CFL1/PKD2/DVL1/KIF20B/FZD2/PFN1/STIL	26
BP	GO:0001823	mesonephros development	18/2112	102/18670	0.03671	0.1291	0.09327	SFRP1/CRLF1/BMP4/SOX9/ZBTB16/GLI3/FOXC1/SIX1/SIX2/FGF2/PBX1/DCHS1/SMAD3/FAT4/PKD2/REN/CAT/HOXA11	18
BP	GO:0007520	myoblast fusion	9/2112	41/18670	0.03676	0.1291	0.09327	CXCL9/PLEKHO1/CDON/IL4R/CXCL10/CD53/CD9/CD81/CFLAR	9
BP	GO:0050873	brown fat cell differentiation	9/2112	41/18670	0.03676	0.1291	0.09327	FTO/SH2B2/ALDH6A1/PLAC8/LEP/ADIPOQ/ARL4A/FABP4/CEBPA	9
BP	GO:0090224	regulation of spindle organization	9/2112	41/18670	0.03676	0.1291	0.09327	TACC3/PLK1/TPX2/BORA/TPR/MAP9/STAG2/CHMP2B/CHMP1B	9
BP	GO:0090317	negative regulation of intracellular protein transport	9/2112	41/18670	0.03676	0.1291	0.09327	ANGPT1/ITGB1BP1/CD36/BARD1/GDI1/ADIPOQ/UBE2J1/FERMT1/UBE2G2	9
BP	GO:0050810	regulation of steroid biosynthetic process	17/2112	95/18670	0.03691	0.1294	0.09353	AKR1C3/ABCG1/PMVK/ERLIN1/SP1/SOD1/ACACB/NFKB1/SC5D/LEP/IFNG/NFYA/ERLIN2/GFI1/MBTPS2/DKK3/IL1B	17
BP	GO:0043470	regulation of carbohydrate catabolic process	16/2112	88/18670	0.03695	0.1294	0.09353	IGF1/ZBTB20/SLC2A6/CBFA2T3/NUP93/HDAC4/TPR/NUP160/HTR2A/IFNG/ARNT/PPP1CA/SCARB2/NUP88/NUP50/TP53	16
BP	GO:1901863	positive regulation of muscle tissue development	16/2112	88/18670	0.03695	0.1294	0.09353	BMP4/IGF1/PIM1/CDON/ZFPM2/BMPR1A/SHOX2/YAP1/FGF2/TGFBR3/CDK1/NOTCH1/ARNTL/CCNB1/HEY2/FGF9	16
BP	GO:2000177	regulation of neural precursor cell proliferation	16/2112	88/18670	0.03695	0.1294	0.09353	ASPM/GLI3/CDON/GATA2/SMARCD3/SPINT2/CX3CR1/PTN/CDH2/FOXO1/NOTCH1/FOXO3/LYN/SHCBP1/TP53/LIMS2	16
BP	GO:0002763	positive regulation of myeloid leukocyte differentiation	11/2112	54/18670	0.03704	0.1296	0.09364	KITLG/CD74/HCLS1/EVI2B/CCR1/LEF1/CA2/ZFP36L1/IFNG/TESC/RB1	11
BP	GO:0006636	unsaturated fatty acid biosynthetic process	11/2112	54/18670	0.03704	0.1296	0.09364	LTC4S/AKR1C3/CD74/HPGDS/FABP5/PTGS1/ELOVL4/ELOVL2/IL1B/ALOX5/ELOVL5	11
BP	GO:0046883	regulation of hormone secretion	40/2112	266/18670	0.03713	0.1299	0.09383	CCL5/SFRP1/SRI/INHBA/OXCT1/PPP3CA/TCIRG1/JAK2/ITSN1/EGFR/KLF7/TM7SF3/TAC1/PASK/MPC2/NMB/TCF7L2/PER2/LRP5/EFNA5/PTPN11/RBP4/ARNTL/SLC25A4/LEP/SSTR5/AGTR1/IFNG/ADIPOQ/STX4/HFE/CD38/SYBU/ENSA/SLC25A5/REN/HADH/IL1B/RAB11FIP1/GPR27	40
BP	GO:0008016	regulation of heart contraction	38/2112	251/18670	0.03781	0.1318	0.09524	GCH1/SRI/SEMA3A/CACNA2D1/ANK2/KCNK1/NPR2/FXYD1/JAK2/FXYD6/HDAC4/HBEGF/ADA/KCNJ5/TAC1/ADORA3/FGF13/AHCYL1/PLN/ASPH/KCNJ2/TRPC1/ATP1B1/SCN1B/IRX5/DSC2/ATP1A2/HEY2/SLC8A1/POPDC2/RYR3/GSTO1/GJC1/GSTM2/SNTA1/THRA/GPD1L/ATP2A3	38
BP	GO:0019218	regulation of steroid metabolic process	21/2112	124/18670	0.03822	0.1318	0.09524	AKR1C3/ACADVL/ABCG1/PMVK/ERLIN1/SP1/SOD1/ACACB/NFKB1/SC5D/LEP/AGTR1/IFNG/NFYA/ERLIN2/GFI1/MBTPS2/ACADL/DKK3/IL1B/EPHX2	21
BP	GO:0007626	locomotory behavior	31/2112	198/18670	0.03823	0.1318	0.09524	UCHL1/ANKH/ZIC1/PENK/IDO1/TMOD1/NPY1R/PBX3/MEIS1/ZFHX3/GLRB/OXR1/NOVA1/SLC18A2/SOBP/ETV5/NPC1/HPGDS/SOD1/FZD4/ADAM22/NAV2/ATP1A2/MECP2/HOXD10/SNCG/C12orf10/HIPK2/FEZF2/B4GALT2/CHL1	31
BP	GO:0003203	endocardial cushion morphogenesis	8/2112	35/18670	0.03832	0.1318	0.09524	SOX9/BMPR1A/TMEM100/DCHS1/NOTCH1/HEY2/ACVR1/HEY1	8
BP	GO:0010259	multicellular organism aging	8/2112	35/18670	0.03832	0.1318	0.09524	CRYAB/COMP/TP63/LEP/SEC63/INPP5D/ERCC1/TP53	8
BP	GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway	8/2112	35/18670	0.03832	0.1318	0.09524	TNFAIP3/BIRC3/NOD2/RIPK2/NFKBIA/IKBKG/PTPN22/NOD1	8
BP	GO:0098751	bone cell development	8/2112	35/18670	0.03832	0.1318	0.09524	FLI1/MEIS1/PTPN6/PTPN11/PIP4K2A/SH2B3/WASF2/LILRB1	8
BP	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	8/2112	35/18670	0.03832	0.1318	0.09524	TFDP2/GZMB/BID/BAK1/TP63/PMAIP1/TP53BP2/TP53	8
BP	GO:0009896	positive regulation of catabolic process	60/2112	423/18670	0.03833	0.1318	0.09524	FTO/TNFAIP3/IGF1/CLU/TNFRSF1B/ZBTB20/SOX9/DTL/AREL1/CBFA2T3/ADAM8/CTSC/PLK1/PIP4K2B/RIPK2/CHFR/DCN/BARD1/BAG2/NDUFA13/HTR2A/TRIM21/FOXO1/EDEM1/PLK2/VCP/ZFP36L1/MYLIP/IFNG/ARNT/TOB1/RGN/DACT1/IKBKG/TRIM22/PINK1/IL6/RNF19B/PIP4K2A/FOXO3/PRKD1/SESN1/NOD1/EPM2A/CUL4B/CEBPA/KDR/DVL1/CD81/EDEM2/ZC3HAV1/ZFP36L2/PRR5L/FYCO1/WAC/BNIP3L/PIM2/AURKA/RNF14/IL1B	60
BP	GO:0002863	positive regulation of inflammatory response to antigenic stimulus	4/2112	12/18670	0.03836	0.1318	0.09524	CCR7/HLA-E/BTK/CD81	4
BP	GO:0014889	muscle atrophy	4/2112	12/18670	0.03836	0.1318	0.09524	IL15/FOXO3/CFLAR/GSN	4
BP	GO:0016045	detection of bacterium	4/2112	12/18670	0.03836	0.1318	0.09524	TLR2/NOD2/NOD1/TLR6	4
BP	GO:0030208	dermatan sulfate biosynthetic process	4/2112	12/18670	0.03836	0.1318	0.09524	DCN/BGN/CSPG4/VCAN	4
BP	GO:0031507	heterochromatin assembly	4/2112	12/18670	0.03836	0.1318	0.09524	TPR/HELLS/HMGA1/SMCHD1	4
BP	GO:0042340	keratan sulfate catabolic process	4/2112	12/18670	0.03836	0.1318	0.09524	PRELP/FMOD/OGN/LUM	4
BP	GO:0042368	vitamin D biosynthetic process	4/2112	12/18670	0.03836	0.1318	0.09524	NFKB1/IFNG/GFI1/IL1B	4
BP	GO:0042659	regulation of cell fate specification	4/2112	12/18670	0.03836	0.1318	0.09524	AR/BMPR1A/FGF2/FZD7	4
BP	GO:0045416	positive regulation of interleukin-8 biosynthetic process	4/2112	12/18670	0.03836	0.1318	0.09524	TLR8/CD74/CLEC7A/SYK	4
BP	GO:0048302	regulation of isotype switching to IgG isotypes	4/2112	12/18670	0.03836	0.1318	0.09524	PTPRC/IL27RA/CD40/TBX21	4
BP	GO:0051481	negative regulation of cytosolic calcium ion concentration	4/2112	12/18670	0.03836	0.1318	0.09524	SMAD3/ATP1A2/SLC8A1/RYR3	4
BP	GO:0051988	regulation of attachment of spindle microtubules to kinetochore	4/2112	12/18670	0.03836	0.1318	0.09524	NEK2/RACGAP1/ECT2/CCNB1	4
BP	GO:0070243	regulation of thymocyte apoptotic process	4/2112	12/18670	0.03836	0.1318	0.09524	BMP4/ADAM8/ADA/TP53	4
BP	GO:0071472	cellular response to salt stress	4/2112	12/18670	0.03836	0.1318	0.09524	AKR1B1/MICU1/ZFP36L1/SLC25A23	4
BP	GO:0072540	T-helper 17 cell lineage commitment	4/2112	12/18670	0.03836	0.1318	0.09524	BATF/IRF4/TBX21/IL6	4
BP	GO:0097284	hepatocyte apoptotic process	4/2112	12/18670	0.03836	0.1318	0.09524	BID/RB1/CFLAR/GSN	4
BP	GO:1902916	positive regulation of protein polyubiquitination	4/2112	12/18670	0.03836	0.1318	0.09524	NOD2/NMI/UBE2D1/PTPN22	4
BP	GO:1904181	positive regulation of membrane depolarization	4/2112	12/18670	0.03836	0.1318	0.09524	DCN/MYOC/PARP1/KDR	4
BP	GO:2000105	positive regulation of DNA-dependent DNA replication	4/2112	12/18670	0.03836	0.1318	0.09524	E2F8/ATRX/CDC7/DBF4	4
BP	GO:2000121	regulation of removal of superoxide radicals	4/2112	12/18670	0.03836	0.1318	0.09524	GCH1/CD36/FBLN5/RGN	4
BP	GO:2001198	regulation of dendritic cell differentiation	4/2112	12/18670	0.03836	0.1318	0.09524	LILRB2/HLA-G/LGALS9/LILRB1	4
BP	GO:0007405	neuroblast proliferation	12/2112	61/18670	0.03858	0.1318	0.09524	ASPM/GLI3/SOX5/EML1/FGF13/SMARCD3/CX3CR1/PTN/LEF1/RACGAP1/NOTCH1/TP53	12
BP	GO:0071384	cellular response to corticosteroid stimulus	12/2112	61/18670	0.03858	0.1318	0.09524	AKR1C3/ICAM1/EGFR/PCK1/FOXO1/ZFP36L1/SSTR5/FLT3/AKAP13/FOXO3/CFLAR/ZFP36L2	12
BP	GO:0007413	axonal fasciculation	6/2112	23/18670	0.03863	0.1318	0.09524	EPHA3/NDN/SEMA3A/MEGF8/CRTAC1/FEZF2	6
BP	GO:0009226	nucleotide-sugar biosynthetic process	6/2112	23/18670	0.03863	0.1318	0.09524	UGDH/NANS/NAGK/GFPT1/UGP2/GFPT2	6
BP	GO:0015813	L-glutamate transmembrane transport	6/2112	23/18670	0.03863	0.1318	0.09524	SLC1A3/SLC25A22/PER2/ARL6IP5/ATP1A2/PRAF2	6
BP	GO:0032331	negative regulation of chondrocyte differentiation	6/2112	23/18670	0.03863	0.1318	0.09524	GDF5/BMP4/PTHLH/SOX9/LTBP3/EFEMP1	6
BP	GO:0034123	positive regulation of toll-like receptor signaling pathway	6/2112	23/18670	0.03863	0.1318	0.09524	TLR2/TLR5/MFHAS1/PTPN22/NR1H3/CYBA	6
BP	GO:0042454	ribonucleoside catabolic process	6/2112	23/18670	0.03863	0.1318	0.09524	UPP1/APOBEC3G/APOBEC3B/ADA/PNP/ENTPD4	6
BP	GO:0051570	regulation of histone H3-K9 methylation	6/2112	23/18670	0.03863	0.1318	0.09524	DNMT1/ATRX/PAX5/MECP2/JARID2/LMNA	6
BP	GO:0070977	bone maturation	6/2112	23/18670	0.03863	0.1318	0.09524	IGF1/SEMA4D/DCHS1/LEP/FAT4/MBTPS2	6
BP	GO:0072215	regulation of metanephros development	6/2112	23/18670	0.03863	0.1318	0.09524	BMP4/STAT1/YAP1/ADIPOQ/WWTR1/FAT4	6
BP	GO:0086012	membrane depolarization during cardiac muscle cell action potential	6/2112	23/18670	0.03863	0.1318	0.09524	CACNA2D1/ANK2/KCNJ2/SCN1B/ATP1A2/SLC8A1	6
BP	GO:0106030	neuron projection fasciculation	6/2112	23/18670	0.03863	0.1318	0.09524	EPHA3/NDN/SEMA3A/MEGF8/CRTAC1/FEZF2	6
BP	GO:1903429	regulation of cell maturation	6/2112	23/18670	0.03863	0.1318	0.09524	NPR2/CLEC7A/EDNRB/TRIM58/BCL11A/AURKA	6
BP	GO:1900371	regulation of purine nucleotide biosynthetic process	20/2112	117/18670	0.03889	0.1326	0.09582	PID1/IGF1/ZBTB20/SLC2A6/CBFA2T3/NUP93/HDAC4/TPR/NUP160/HTR2A/VCP/IFNG/ARNT/PDK4/PARP1/PINK1/GUCA1A/NUP88/NUP50/TP53	20
BP	GO:0032232	negative regulation of actin filament bundle assembly	7/2112	29/18670	0.03915	0.1333	0.0963	DLC1/WAS/CORO2B/MYOC/WASF2/S1PR1/PFN1	7
BP	GO:0044030	regulation of DNA methylation	7/2112	29/18670	0.03915	0.1333	0.0963	KMT2A/PIK3CA/MECP2/MPHOSPH8/RLF/PARP1/SPI1	7
BP	GO:0060441	epithelial tube branching involved in lung morphogenesis	7/2112	29/18670	0.03915	0.1333	0.0963	BMP4/DLG5/SOX9/YAP1/DAG1/HOXA5/CTSH	7
BP	GO:0061387	regulation of extent of cell growth	19/2112	110/18670	0.03947	0.1342	0.097	SEMA4A/SEMA4D/SEMA3A/FGF13/TRPV2/RYK/PTPRS/SEMA3F/EFNA5/GDI1/PAK1/CTTN/MAP1B/ARHGAP4/MEGF8/DPYSL2/SEMA4F/SEMA3E/SEMA6B	19
BP	GO:0098739	import across plasma membrane	19/2112	110/18670	0.03947	0.1342	0.097	CACNA2D1/KCNJ5/SLC1A3/SLC39A8/PER2/KCNJ15/KCNJ2/ARL6IP5/ATP1B1/KCNJ8/IFNG/ATP1A2/SLC8A1/SLC12A2/SLC12A8/HFE/SLC39A6/SLC12A7/SLC2A5	19
BP	GO:0051648	vesicle localization	45/2112	306/18670	0.03965	0.1345	0.09717	SERPINA1/RASGRP1/MREG/ITGA4/PREPL/PRKCB/PFN2/LRMP/CTSC/GOLGA2/TRAK2/WASL/DNM1/F5/KIF3B/SEC31A/MAGI2/NLGN1/PCDH17/TMEM230/CDH2/DYNC1I1/HTR2A/CHRNA5/RAB27A/FNBP1L/SYT17/MYO1C/STX4/ANKRD28/IKBKG/VAMP2/STXBP1/PINK1/BACE1/SYBU/AP1AR/DVL1/FYCO1/CNIH1/CASK/KIF1B/P2RY4/CADPS/KIF23	45
BP	GO:0002063	chondrocyte development	10/2112	48/18670	0.03969	0.1345	0.09717	SCARA3/PTHLH/FGF18/SOX9/SULF1/COCH/COMP/SHOX2/COL14A1/CHST11	10
BP	GO:0030865	cortical cytoskeleton organization	10/2112	48/18670	0.03969	0.1345	0.09717	EPB41L2/WASL/WAS/PLEK/NLGN1/NCKAP1L/RACGAP1/ECT2/WDR1/KIF23	10
BP	GO:0045912	negative regulation of carbohydrate metabolic process	10/2112	48/18670	0.03969	0.1345	0.09717	ENPP1/CBFA2T3/HDAC4/PASK/PLEK/SIK1/COX11/FAM3C/ADIPOQ/TP53	10
BP	GO:0051653	spindle localization	10/2112	48/18670	0.03969	0.1345	0.09717	ASPM/NUSAP1/MAP4/NDC80/MAD2L1/PLK1/WASL/MCPH1/ACTR3/ACTR2	10
BP	GO:0051972	regulation of telomerase activity	10/2112	48/18670	0.03969	0.1345	0.09717	PRKCQ/NEK7/NEK2/TERF1/HSP90AB1/PARP4/AURKB/TP53/PARM1/PARN	10
BP	GO:0060324	face development	10/2112	48/18670	0.03969	0.1345	0.09717	PLEKHA1/LRP6/SKI/SGPL1/ASPH/RRAS/LEF1/PTPN11/TGFB3/NIPBL	10
BP	GO:0046173	polyol biosynthetic process	14/2112	75/18670	0.0402	0.1361	0.09831	GCH1/PLCE1/PCBD1/AKR1B1/FGF2/SPHK1/PLCG2/PLEK/PCK1/HRH1/LEP/P2RY6/PPIP5K1/PTH1R	14
BP	GO:0051303	establishment of chromosome localization	14/2112	75/18670	0.0402	0.1361	0.09831	NDC80/GEM/UBE2B/CDCA8/DLGAP5/KIF2C/CCNB1/TERF1/CENPF/CHMP2B/ACTR3/KIFC1/ACTR2/CHMP1B	14
BP	GO:0030516	regulation of axon extension	17/2112	96/18670	0.04031	0.1363	0.09845	SEMA4A/SEMA4D/SEMA3A/TRPV2/RYK/PTPRS/SEMA3F/GDI1/PAK1/CTTN/MAP1B/ARHGAP4/MEGF8/DPYSL2/SEMA4F/SEMA3E/SEMA6B	17
BP	GO:0042632	cholesterol homeostasis	17/2112	96/18670	0.04031	0.1363	0.09845	ABCG1/NFE2L1/AKR1C1/NPC1/LRP5/LIPG/MYLIP/CETP/NR1H3/IL18/FABP4/RALY/ACSM3/LIPC/MED13/EPHX2/SOAT2	17
BP	GO:0045995	regulation of embryonic development	22/2112	132/18670	0.04037	0.1363	0.09849	SFRP1/BMP4/IGF1/AR/SULF1/LAMA2/SIX1/BMPR1A/GATA2/DAG1/CDK1/FZD7/RACGAP1/NOTCH1/ADIPOQ/NIPBL/TULP3/IL1RN/DVL1/TENM4/FZD2/RAB14	22
BP	GO:0072329	monocarboxylic acid catabolic process	22/2112	132/18670	0.04037	0.1363	0.09849	FAH/ALDH3A2/ACADVL/ACOX2/ECHDC2/ACAT1/PCK1/ETFB/ACACB/PGD/PCCA/IDUA/LEP/BDH2/ECI2/ADIPOQ/ECI1/ACADL/HADH/ECHS1/ALDH5A1/HADHA	22
BP	GO:0055013	cardiac muscle cell development	16/2112	89/18670	0.0405	0.1367	0.09875	SGCB/BMP4/IGF1/MYH10/CDK1/SORBS2/PDLIM5/SGCD/CCNB1/HEY2/SLC8A1/PAK1/AKAP13/MYH11/LMNA/ALPK3	16
BP	GO:0006805	xenobiotic metabolic process	21/2112	125/18670	0.04123	0.139	0.1004	CDO1/NQO1/EPHX1/FMO2/GSTM5/GSTM3/GSTA4/BPHL/CYB5R3/AKR1C1/GHR/ARNT/HSP90AB1/AOC2/PTGS1/CYP46A1/GSTO1/AOC3/GSTM2/AKR7A2/EPHX2	21
BP	GO:0009063	cellular amino acid catabolic process	21/2112	125/18670	0.04123	0.139	0.1004	FAH/CDO1/IDO1/ALDH7A1/PCYOX1/KYNU/ALDH6A1/CBS/PCBD1/OAT/DDAH2/MCCC1/ASPA/ACAT1/HPD/MAT1A/KMO/BCKDHB/AASS/ALDH5A1/TXN2	21
BP	GO:0010212	response to ionizing radiation	24/2112	147/18670	0.0413	0.1391	0.1005	SFRP1/PTPRC/NUCKS1/ICAM1/CRYAB/YAP1/CXCL10/BLM/BAK1/NOX4/NET1/ECT2/CCL7/CCND1/PARP1/NIPBL/CYBA/RAD51AP1/ERCC1/ALAD/TP53/TOPBP1/PML/GTF2H5	24
BP	GO:0043524	negative regulation of neuron apoptotic process	24/2112	147/18670	0.0413	0.1391	0.1005	NDNF/CRLF1/GDF5/CORO1A/NTRK2/ANGPT1/AXL/OXR1/SIX1/ADAM8/JAK2/ITSN1/CX3CR1/SOD1/ZPR1/PIK3CA/MECP2/HSP90AB1/STXBP1/TGFB3/PINK1/HIPK2/CCL2/CHL1	24
BP	GO:0006733	oxidoreduction coenzyme metabolic process	32/2112	207/18670	0.04159	0.1398	0.101	IGF1/NT5E/IDO1/ZBTB20/FMO2/KYNU/SLC2A6/CBFA2T3/NUP93/HDAC4/HK3/ALDOC/MPC2/IDH2/TPR/NUP160/RPIA/HTR2A/PGD/VCP/IFNG/ARNT/KMO/NDUFA9/MDH1/CD38/MPC1/NUP88/NUP50/TP53/TALDO1/GPD1L	32
BP	GO:0030073	insulin secretion	32/2112	207/18670	0.04159	0.1398	0.101	CCL5/SFRP1/SRI/OXCT1/PPP3CA/TCIRG1/JAK2/KLF7/TM7SF3/MPC2/CYB5R4/TCF7L2/PER2/LRP5/EFNA5/PTPN11/RBP4/ARNTL/SLC25A4/LEP/SSTR5/IFNG/STX4/CD38/SYBU/ENSA/IL1RN/SLC25A5/HADH/RAB11FIP2/IL1B/GPR27	32
BP	GO:0071456	cellular response to hypoxia	32/2112	207/18670	0.04159	0.1398	0.101	PSMB9/NDNF/SFRP1/PSMB8/PSMB10/ICAM1/ADAM8/PSME1/CPEB1/CREBBP/KCNK2/CCNA2/PCK1/PTN/PMAIP1/BACH1/FAM162A/NOTCH1/HIGD1A/ZFP36L1/ARNT/CCNB1/SLC8A1/PINK1/CUL2/FOXO3/LMNA/HIPK2/CFLAR/TP53/BNIP3L/HP1BP3	32
BP	GO:0002090	regulation of receptor internalization	11/2112	55/18670	0.04174	0.1402	0.1013	ANGPT1/TBC1D5/USP46/SELE/PLCG2/MAGI2/LRPAP1/SYK/ATXN2/MTMR2/AHI1	11
BP	GO:0044380	protein localization to cytoskeleton	11/2112	55/18670	0.04174	0.1402	0.1013	MAPRE2/MCPH1/HTR2A/TTK/KLHL21/SNX10/DVL1/KIF20B/GOLGB1/AURKA/STIL	11
BP	GO:0048839	inner ear development	30/2112	192/18670	0.04189	0.1406	0.1016	BMP4/ZIC1/SOX9/GLI3/SIX1/GATA2/SOBP/KCNK2/CCNA2/SOX2/SOD1/DCHS1/PTPN11/NOTCH1/MCM2/HEY2/TFAP2A/LRP10/FGF9/TGFB3/MAPKAPK2/FZD6/FAT4/ADAM10/CEBPA/DVL1/MYO3A/FZD2/MYCL/AHI1	30
BP	GO:0030808	regulation of nucleotide biosynthetic process	20/2112	118/18670	0.04203	0.141	0.1019	PID1/IGF1/ZBTB20/SLC2A6/CBFA2T3/NUP93/HDAC4/TPR/NUP160/HTR2A/VCP/IFNG/ARNT/PDK4/PARP1/PINK1/GUCA1A/NUP88/NUP50/TP53	20
BP	GO:0010677	negative regulation of cellular carbohydrate metabolic process	9/2112	42/18670	0.04227	0.1416	0.1023	ENPP1/CBFA2T3/HDAC4/PASK/PLEK/SIK1/COX11/FAM3C/ADIPOQ	9
BP	GO:0051154	negative regulation of striated muscle cell differentiation	9/2112	42/18670	0.04227	0.1416	0.1023	HDAC4/CXCL10/EZH2/CEACAM5/BHLHE41/FZD7/NOTCH1/PAK1/CFLAR	9
BP	GO:0099622	cardiac muscle cell membrane repolarization	9/2112	42/18670	0.04227	0.1416	0.1023	CACNA2D1/ANK2/KCNJ5/KCNJ2/ATP1B1/SCN1B/KCNJ8/WDR1/SNTA1	9
BP	GO:0034620	cellular response to unfolded protein	23/2112	140/18670	0.04236	0.1418	0.1025	PIK3R1/ACADVL/PTPN2/EXTL2/TM7SF3/HSPA6/CXCL8/SEC31A/CREB3L2/BAK1/TSPYL2/EDEM1/KDELR3/VCP/GFPT1/FKBP14/CCND1/DDIT3/LMNA/MBTPS2/HSPA1L/TATDN2/CCL2	23
BP	GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus	12/2112	62/18670	0.0431	0.1441	0.1041	PTPRC/BCL11B/IL27RA/BATF/CD40/TFRC/TCF7/TBX21/CD40LG/LEF1/ERCC1/THOC1	12
BP	GO:0016444	somatic cell DNA recombination	12/2112	62/18670	0.0431	0.1441	0.1041	PTPRC/BCL11B/IL27RA/BATF/CD40/TFRC/TCF7/TBX21/CD40LG/LEF1/ERCC1/THOC1	12
BP	GO:0032922	circadian regulation of gene expression	12/2112	62/18670	0.0431	0.1441	0.1041	RELB/ZFHX3/KMT2A/PER2/BHLHE41/ARNTL/GFPT1/PPP1CA/PER3/NRIP1/KDM2A/PML	12
BP	GO:0007224	smoothened signaling pathway	22/2112	133/18670	0.0434	0.1449	0.1047	ENPP1/GAS1/CD3E/SFRP1/BMP4/ZIC1/DLG5/TMEM231/GLI3/CDON/SHOX2/CREBBP/DZIP1/TCTN1/FGF9/TULP3/MEGF8/RB1/HIPK2/ARL3/RFX4/STIL	22
BP	GO:0031023	microtubule organizing center organization	22/2112	133/18670	0.0434	0.1449	0.1047	CETN2/GOLGA2/PLK1/KIF11/KIF3B/CDK1/MAP9/CEP135/MCPH1/ARHGEF10/NEK2/PLK2/CETN3/CEP85/CHMP2B/CEP68/CEP63/PKD2/CCNF/AURKA/CHMP1B/STIL	22
BP	GO:0014020	primary neural tube formation	17/2112	97/18670	0.04392	0.1464	0.1058	SFRP1/BMP4/LRP6/SKI/COBL/DLC1/SPINT2/VASP/TULP3/APAF1/FZD6/CFL1/DVL1/KIF20B/FZD2/PFN1/STIL	17
BP	GO:0055092	sterol homeostasis	17/2112	97/18670	0.04392	0.1464	0.1058	ABCG1/NFE2L1/AKR1C1/NPC1/LRP5/LIPG/MYLIP/CETP/NR1H3/IL18/FABP4/RALY/ACSM3/LIPC/MED13/EPHX2/SOAT2	17
BP	GO:0050771	negative regulation of axonogenesis	13/2112	69/18670	0.04393	0.1464	0.1058	SEMA4A/SEMA4D/SEMA3A/TRAK2/FGF13/RYK/PTPRS/SEMA3F/GDI1/ARHGAP4/SEMA4F/SEMA3E/SEMA6B	13
BP	GO:0007623	circadian rhythm	32/2112	208/18670	0.04402	0.1466	0.1059	RELB/NTRK2/ZFHX3/EGFR/ADA/KMT2A/OPN3/CDK1/SIK1/NLGN1/EZH2/ID3/PER2/TOP2A/BHLHE41/ARNTL/GFPT1/LEP/TIMELESS/PPP1CA/ADIPOQ/PHLPP1/NDUFA9/HEBP1/PER3/TYMS/NR1H3/TP53/USP7/NRIP1/KDM2A/PML	32
BP	GO:0035148	tube formation	24/2112	148/18670	0.04421	0.1471	0.1063	SFRP1/BMP4/LRP6/SOX9/SKI/ITGB1BP1/SIX1/COBL/DLC1/NFIB/SPINT2/TCTN1/VASP/NOTCH1/TULP3/APAF1/FZD6/CFL1/DVL1/KIF20B/TGM2/FZD2/PFN1/STIL	24
BP	GO:0061041	regulation of wound healing	24/2112	148/18670	0.04421	0.1471	0.1063	TNFAIP3/CXCR4/PRKCQ/CD36/PDPN/HBEGF/PROS1/FGF2/CLEC7A/PLEK/VKORC1/PLAT/SMAD3/CD9/KANK1/SYK/TEC/PRKG1/TFPI/LYN/SH2B3/MYLK/GP1BA/CASK	24
BP	GO:0001843	neural tube closure	16/2112	90/18670	0.04428	0.1472	0.1064	SFRP1/BMP4/LRP6/SKI/COBL/DLC1/SPINT2/VASP/TULP3/APAF1/FZD6/DVL1/KIF20B/FZD2/PFN1/STIL	16
BP	GO:0007492	endoderm development	14/2112	76/18670	0.04435	0.1472	0.1064	BMP4/ITGA4/INHBA/ITGB2/BMPR1A/BPTF/COL8A1/SOX2/SMAD3/NOTCH1/KIF16B/ZFP36L1/PAF1/ITGAV	14
BP	GO:0050000	chromosome localization	14/2112	76/18670	0.04435	0.1472	0.1064	NDC80/GEM/UBE2B/CDCA8/DLGAP5/KIF2C/CCNB1/TERF1/CENPF/CHMP2B/ACTR3/KIFC1/ACTR2/CHMP1B	14
BP	GO:0098659	inorganic cation import across plasma membrane	15/2112	83/18670	0.04444	0.1472	0.1064	CACNA2D1/KCNJ5/SLC39A8/KCNJ15/KCNJ2/ATP1B1/KCNJ8/IFNG/ATP1A2/SLC8A1/SLC12A2/SLC12A8/HFE/SLC39A6/SLC12A7	15
BP	GO:0099587	inorganic ion import across plasma membrane	15/2112	83/18670	0.04444	0.1472	0.1064	CACNA2D1/KCNJ5/SLC39A8/KCNJ15/KCNJ2/ATP1B1/KCNJ8/IFNG/ATP1A2/SLC8A1/SLC12A2/SLC12A8/HFE/SLC39A6/SLC12A7	15
BP	GO:0014808	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	8/2112	36/18670	0.04456	0.1472	0.1064	CCR5/SRI/ANK2/PLN/ATP1A2/SLC8A1/GSTO1/GSTM2	8
BP	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	8/2112	36/18670	0.04456	0.1472	0.1064	FGF18/PRKCB/PRKD2/FZD4/TNMD/ARNT/FGF9/IL1B	8
BP	GO:0035137	hindlimb morphogenesis	8/2112	36/18670	0.04456	0.1472	0.1064	GDF5/BMP4/ZBTB16/BMPR1A/TP63/PITX1/NOTCH1/HOXD10	8
BP	GO:0035872	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	8/2112	36/18670	0.04456	0.1472	0.1064	TNFAIP3/BIRC3/NOD2/RIPK2/NFKBIA/IKBKG/PTPN22/NOD1	8
BP	GO:0071634	regulation of transforming growth factor beta production	8/2112	36/18670	0.04456	0.1472	0.1064	XCL1/CD200/LGALS9/LUM/SMAD3/HSP90AB1/LRRC32/ITGAV	8
BP	GO:0071709	membrane assembly	8/2112	36/18670	0.04456	0.1472	0.1064	RFTN1/EMP2/PTPRD/MAGI2/NLGN1/CDH2/UGCG/SPTBN1	8
BP	GO:1901020	negative regulation of calcium ion transmembrane transporter activity	8/2112	36/18670	0.04456	0.1472	0.1064	SRI/DYSF/GEM/PLN/ATP1A2/PKD2/GSTO1/GSTM2	8
BP	GO:2001171	positive regulation of ATP biosynthetic process	8/2112	36/18670	0.04456	0.1472	0.1064	PID1/IGF1/ZBTB20/HTR2A/VCP/IFNG/ARNT/PINK1	8
BP	GO:0090150	establishment of protein localization to membrane	48/2112	332/18670	0.04457	0.1472	0.1064	TFDP2/RTP4/CSK/MICALL1/RFTN1/PREPL/RAB8A/PARD3/GZMB/BID/ITGB1BP1/ITGB2/PEX26/SEC62/RPL31/EGFR/NPC1/RPL24/ERBB2/CLSTN1/TP63/NDUFA13/PMAIP1/ATP1B1/VPS37C/ICMT/GDI1/SEC63/RPS4X/ZDHHC18/PAK1/RPL12/MYO1C/ATG3/BBS1/PEX19/VAMP2/UBL4A/TP53BP2/RPL15/NCF1/GOLGA7/RPL10A/TP53/ZDHHC14/SPTBN1/MOAP1/RPS14	48
BP	GO:0099173	postsynapse organization	26/2112	163/18670	0.04459	0.1472	0.1064	LILRB2/MYH10/DOCK10/ZNF365/GLRB/PTPRD/WASL/ETV5/MAGI2/ARHGAP22/NLGN1/EPHB1/PTN/PDLIM5/CDH2/PTPRS/SEMA3F/CTTN/CHMP2B/CFL1/ADAM10/DVL1/WASF2/ABI2/MTMR2/ACTR2	26
BP	GO:0002902	regulation of B cell apoptotic process	5/2112	18/18670	0.04488	0.1472	0.1064	CD74/ADA/BTK/AURKB/LYN	5
BP	GO:0007221	positive regulation of transcription of Notch receptor target	5/2112	18/18670	0.04488	0.1472	0.1064	STAT1/CREBBP/DLGAP5/PBX1/NOTCH1	5
BP	GO:0031065	positive regulation of histone deacetylation	5/2112	18/18670	0.04488	0.1472	0.1064	PRKD2/NIPBL/PINK1/PRKD1/TP53	5
BP	GO:0042095	interferon-gamma biosynthetic process	5/2112	18/18670	0.04488	0.1472	0.1064	TLR8/INHBA/CLEC7A/IL18/LILRB1	5
BP	GO:0048339	paraxial mesoderm development	5/2112	18/18670	0.04488	0.1472	0.1064	FOXC1/BMPR1A/YAP1/LEF1/SMAD3	5
BP	GO:0048557	embryonic digestive tract morphogenesis	5/2112	18/18670	0.04488	0.1472	0.1064	GLI3/SIX2/SHOX2/TCF7/NIPBL	5
BP	GO:0070230	positive regulation of lymphocyte apoptotic process	5/2112	18/18670	0.04488	0.1472	0.1064	CCL5/IDO1/LGALS9/ADAM8/TP53	5
BP	GO:0071605	monocyte chemotactic protein-1 production	5/2112	18/18670	0.04488	0.1472	0.1064	LGALS9/CLEC7A/ADIPOQ/SYK/IL1B	5
BP	GO:0071637	regulation of monocyte chemotactic protein-1 production	5/2112	18/18670	0.04488	0.1472	0.1064	LGALS9/CLEC7A/ADIPOQ/SYK/IL1B	5
BP	GO:0072574	hepatocyte proliferation	5/2112	18/18670	0.04488	0.1472	0.1064	TNFAIP3/RPS6KA1/PTN/CFLAR/LIMS2	5
BP	GO:0072575	epithelial cell proliferation involved in liver morphogenesis	5/2112	18/18670	0.04488	0.1472	0.1064	TNFAIP3/RPS6KA1/PTN/CFLAR/LIMS2	5
BP	GO:0150079	negative regulation of neuroinflammatory response	5/2112	18/18670	0.04488	0.1472	0.1064	PTPRC/IGF1/TNFRSF1B/CST7/CD200	5
BP	GO:0002534	cytokine production involved in inflammatory response	10/2112	49/18670	0.04501	0.1474	0.1065	IDO1/MYD88/NOD2/CD96/GPSM3/CLEC7A/C5orf30/CD6/LEP/TLR6	10
BP	GO:0002686	negative regulation of leukocyte migration	10/2112	49/18670	0.04501	0.1474	0.1065	SLAMF8/IL27RA/CD200/WASL/ADA/GPR18/CCL21/NBL1/PTGER4/CCL2	10
BP	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	10/2112	49/18670	0.04501	0.1474	0.1065	SFRP1/PTPRC/TIMP3/INHBA/BID/TNFSF10/PMAIP1/PPP1CA/G0S2/PML	10
BP	GO:0010769	regulation of cell morphogenesis involved in differentiation	44/2112	301/18670	0.04515	0.1478	0.1068	GBP1/SEMA4A/SEMA4D/NTRK2/SEMA3A/PPP3CA/ITGB1BP1/PTPRD/TRAK2/SHOX2/TUBB2B/PDPN/FGF13/TRPV2/NLGN1/PDLIM5/DOCK1/CDH2/RYK/PTPRS/SEMA3F/EFNA5/CHN1/MYOC/GDI1/KANK1/PAK1/CTTN/CHODL/MAP1B/ARHGAP4/MEGF8/DPYSL2/CFL1/SEMA4F/AP1AR/FBLN1/SEMA3E/ADAM10/SEMA6B/ABI2/FEZF2/LIMS2/ACTR2	44
BP	GO:0034767	positive regulation of ion transmembrane transport	25/2112	156/18670	0.04592	0.1502	0.1086	CXCL9/XCL1/CCR2/SRI/CACNA2D1/ANK2/FXYD1/CXCL10/PLCG2/KCNJ2/TRPC1/CD19/ATP1B1/IFNG/RGN/CXCL11/FGF14/P2RY6/APLNR/PINK1/TESC/PKD2/GSTO1/GSTM2/CCL2	25
BP	GO:0010634	positive regulation of epithelial cell migration	27/2112	171/18670	0.04606	0.1506	0.1088	BMP4/FGF18/SOX9/ANGPT1/FGF7/MAPRE2/ITGB1BP1/CD40/PRKD2/ANXA3/GATA2/HBEGF/FGF2/TAC1/SP1/DOCK1/HYAL1/PLK2/IFNG/PPM1F/HSPB1/AKT3/PRKD1/KDR/CAPN7/PFN1/CTSH	27
BP	GO:0051491	positive regulation of filopodium assembly	7/2112	30/18670	0.04625	0.1508	0.109	CCR7/WASL/CCL21/NLGN1/FNBP1L/DPYSL3/TGFB3	7
BP	GO:0061037	negative regulation of cartilage development	7/2112	30/18670	0.04625	0.1508	0.109	GDF5/BMP4/PTHLH/SOX9/LTBP3/EFEMP1/LEP	7
BP	GO:0061082	myeloid leukocyte cytokine production	7/2112	30/18670	0.04625	0.1508	0.109	CD74/HLA-G/CD36/DDX58/DDX1/TGFB3/LILRB1	7
BP	GO:0014902	myotube differentiation	19/2112	112/18670	0.04626	0.1508	0.109	CXCL9/IGF1/PLEKHO1/SKI/PPP3CA/CDON/IL4R/SIX1/HDAC4/SHOX2/CXCL10/SIK1/CD53/CEACAM5/BHLHE41/CD9/NOTCH1/CD81/CFLAR	19
BP	GO:0051817	modification of morphology or physiology of other organism involved in symbiotic interaction	19/2112	112/18670	0.04626	0.1508	0.109	CCL5/NUCKS1/CHD1/DAG1/PC/IFI27/CCNT1/SP1/LEF1/SMAD3/FBXL2/KRT6A/TYMS/CFL1/KPNA2/CXCL6/HIPK2/ITGAV/PTX3	19
BP	GO:0006006	glucose metabolic process	32/2112	209/18670	0.04655	0.1511	0.1092	ENPP1/IGF1/NPY1R/NFE2L1/PTPN2/OAS1/HK3/ALDOC/PC/PASK/SIK1/PCK1/PER2/LRP5/COX11/ACACB/FAM3C/PMAIP1/FOXO1/RBP4/LEP/PPP1CA/RGN/PIK3CA/ADIPOQ/FABP5/PDK4/SORBS1/MDH1/TP53/TKTL1/ALDH5A1	32
BP	GO:0000724	double-strand break repair via homologous recombination	22/2112	134/18670	0.04659	0.1511	0.1092	NUCKS1/ZNF365/CDC45/BLM/WAS/MCM5/REV3L/PPP4C/RNF138/FEN1/RMI1/TIMELESS/CDC7/MCM2/PARP1/NIPBL/REC8/MORF4L1/MCM4/RAD51AP1/SMCHD1/ACTR2	22
BP	GO:0001783	B cell apoptotic process	6/2112	24/18670	0.04674	0.1511	0.1092	CD74/ADA/BAK1/BTK/AURKB/LYN	6
BP	GO:0003181	atrioventricular valve morphogenesis	6/2112	24/18670	0.04674	0.1511	0.1092	BMPR1A/DCHS1/NOTCH1/HEY2/ACVR1/HEY1	6
BP	GO:0003272	endocardial cushion formation	6/2112	24/18670	0.04674	0.1511	0.1092	BMPR1A/TMEM100/DCHS1/NOTCH1/HEY2/ACVR1	6
BP	GO:0010288	response to lead ion	6/2112	24/18670	0.04674	0.1511	0.1092	PPP2CA/PPP2CB/PPP1CA/BACE1/CAT/ALAD	6
BP	GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	6/2112	24/18670	0.04674	0.1511	0.1092	ANK2/PLN/ATP1A2/SLC8A1/GSTO1/GSTM2	6
BP	GO:0032925	regulation of activin receptor signaling pathway	6/2112	24/18670	0.04674	0.1511	0.1092	SKI/MAGI2/ACVR1/FGF9/FST/FSTL3	6
BP	GO:0035588	G protein-coupled purinergic receptor signaling pathway	6/2112	24/18670	0.04674	0.1511	0.1092	ADA/GPR171/ADORA3/P2RY6/P2RY14/P2RY4	6
BP	GO:0042537	benzene-containing compound metabolic process	6/2112	24/18670	0.04674	0.1511	0.1092	IDO1/KYNU/GSTM3/CYP4B1/KMO/GSTM2	6
BP	GO:0046135	pyrimidine nucleoside catabolic process	6/2112	24/18670	0.04674	0.1511	0.1092	TYMP/NT5E/UPP1/APOBEC3G/APOBEC3B/ENTPD4	6
BP	GO:0060396	growth hormone receptor signaling pathway	6/2112	24/18670	0.04674	0.1511	0.1092	PIK3R1/JAK2/GHR/SOCS2/PRL/LYN	6
BP	GO:0099563	modification of synaptic structure	6/2112	24/18670	0.04674	0.1511	0.1092	WASF3/MYH10/PFN2/ITSN1/CHMP2B/PFN1	6
BP	GO:1900078	positive regulation of cellular response to insulin stimulus	6/2112	24/18670	0.04674	0.1511	0.1092	NUCKS1/PTPN11/LEP/PAK1/MYO1C/SORBS1	6
BP	GO:2000209	regulation of anoikis	6/2112	24/18670	0.04674	0.1511	0.1092	NTRK2/SIK1/CEACAM5/NOTCH1/PIK3CA/PDK4	6
BP	GO:0000768	syncytium formation by plasma membrane fusion	11/2112	56/18670	0.04684	0.1511	0.1092	CXCL9/PLEKHO1/CDON/IL4R/CXCL10/SH3PXD2A/CD53/CD9/CD81/CFLAR/SBNO2	11
BP	GO:0002381	immunoglobulin production involved in immunoglobulin mediated immune response	11/2112	56/18670	0.04684	0.1511	0.1092	XCL1/PTPRC/IL27RA/BATF/CD40/TFRC/TBX21/CD40LG/BTK/ERCC1/THOC1	11
BP	GO:0090183	regulation of kidney development	11/2112	56/18670	0.04684	0.1511	0.1092	BMP4/STAT1/SOX9/SIX1/PDGFD/SIX2/YAP1/ADIPOQ/WWTR1/FAT4/CFLAR	11
BP	GO:0098586	cellular response to virus	11/2112	56/18670	0.04684	0.1511	0.1092	BIRC3/PENK/CCL19/LGALS9/IRF7/IFIH1/TSPAN6/DDX58/DDX60/ADAR/MMP12	11
BP	GO:0140253	cell-cell fusion	11/2112	56/18670	0.04684	0.1511	0.1092	CXCL9/PLEKHO1/CDON/IL4R/CXCL10/SH3PXD2A/CD53/CD9/CD81/CFLAR/SBNO2	11
BP	GO:1903078	positive regulation of protein localization to plasma membrane	11/2112	56/18670	0.04684	0.1511	0.1092	PIK3R1/EPHA3/PRKCH/EGFR/RHOG/IFNG/STX4/SORBS1/CLIP3/RAB11FIP2/SPTBN1	11
BP	GO:0001841	neural tube formation	18/2112	105/18670	0.04706	0.1517	0.1096	SFRP1/BMP4/LRP6/SKI/COBL/DLC1/SPINT2/TCTN1/VASP/TULP3/APAF1/FZD6/CFL1/DVL1/KIF20B/FZD2/PFN1/STIL	18
BP	GO:1903034	regulation of response to wounding	28/2112	179/18670	0.04743	0.1528	0.1104	TNFAIP3/CXCR4/PRKCQ/CD36/PDPN/HBEGF/PROS1/FGF2/CLEC7A/PLEK/VKORC1/SCARF1/PTPRF/PTN/PLAT/PTPRS/SMAD3/CD9/KANK1/SYK/TEC/PRKG1/TFPI/LYN/SH2B3/MYLK/GP1BA/CASK	28
BP	GO:0008406	gonad development	33/2112	217/18670	0.04749	0.1529	0.1104	KITLG/PLEKHA1/SFRP1/ASPM/HOXA10/SOX9/FOXC1/SEMA3A/INHBA/AKR1C3/RHOBTB3/TNFSF10/AR/ZFPM2/SGPL1/ICAM1/SOD1/BCL2L2/FZD4/ATRX/IRX5/LEP/CCND1/FGF9/REC8/FOXO3/ANG/FSTL3/REN/ERCC1/HOXA11/NRIP1/PTX3	33
BP	GO:0044242	cellular lipid catabolic process	33/2112	217/18670	0.04749	0.1529	0.1104	ALDH3A2/AKR1C3/ACADVL/ACOX2/SGPL1/PNPLA6/SPHK1/ECHDC2/PLCG2/ACAT1/PCK1/ETFB/ACACB/PLA2G4C/PCCA/LIPG/LEP/BDH2/ECI2/FUCA1/ADIPOQ/PRDX6/FABP5/ECI1/AOAH/GLA/FABP4/ABHD6/ACADL/HADH/ECHS1/LIPC/HADHA	33
BP	GO:0001701	in utero embryonic development	53/2112	373/18670	0.0477	0.1535	0.1109	HOPX/CDKN1C/IGF1/MYH10/TMEM231/GLI3/FOXC1/ANGPT1/CCNB2/AR/ZFPM2/BMPR1A/GATA2/EGFR/UBE2B/SH3PXD2A/ADA/E2F8/BPTF/TMEM100/SPINT2/CHST11/NEK2/ZPR1/TCTN1/GINS1/LEF1/SMAD3/NOTCH1/ZFP36L1/PSPH/ARNT/CCNB1/HEY2/ASF1B/ACVR1/FOSL1/TGFB3/KRT19/BTF3/ADAM10/CEBPA/HEY1/SYF2/PKD2/NLE1/FUT8/PRMT1/PTH1R/TP53/TANC2/C6/STIL	53
BP	GO:0046364	monosaccharide biosynthetic process	17/2112	98/18670	0.04776	0.1536	0.111	CHST15/PTPN2/AKR1B1/ALDOC/PC/SIK1/PCK1/PER2/FAM3C/PGD/FOXO1/RBP4/LEP/RGN/ADIPOQ/MDH1/TALDO1	17
BP	GO:1904377	positive regulation of protein localization to cell periphery	12/2112	63/18670	0.04798	0.1542	0.1114	PIK3R1/EPHA3/EPB41L2/PRKCH/EGFR/RHOG/IFNG/STX4/SORBS1/CLIP3/RAB11FIP2/SPTBN1	12
BP	GO:0000096	sulfur amino acid metabolic process	9/2112	43/18670	0.04829	0.1548	0.1118	BHMT2/CDO1/PCYOX1/CBS/AHCYL1/NOX4/MAT1A/AHCYL2/TXN2	9
BP	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress	9/2112	43/18670	0.04829	0.1548	0.1118	JAK2/MELK/SOD1/ARL6IP5/PARP1/HSPB1/PINK1/BAG5/PML	9
BP	GO:0009163	nucleoside biosynthetic process	9/2112	43/18670	0.04829	0.1548	0.1118	TYMP/NT5E/UPP1/ADK/NME7/ADA/NME4/TK2/TK1	9
BP	GO:1990573	potassium ion import across plasma membrane	9/2112	43/18670	0.04829	0.1548	0.1118	KCNJ5/KCNJ15/KCNJ2/ATP1B1/KCNJ8/ATP1A2/SLC12A2/SLC12A8/SLC12A7	9
BP	GO:0030510	regulation of BMP signaling pathway	16/2112	91/18670	0.04831	0.1548	0.1118	SFRP1/GDF5/BMP4/SKI/HTRA1/SULF1/TWSG1/NEO1/NOTCH1/NBL1/TOB1/CHRDL1/FST/HIPK2/FSTL3/CDH5	16
BP	GO:0060606	tube closure	16/2112	91/18670	0.04831	0.1548	0.1118	SFRP1/BMP4/LRP6/SKI/COBL/DLC1/SPINT2/VASP/TULP3/APAF1/FZD6/DVL1/KIF20B/FZD2/PFN1/STIL	16
BP	GO:0061515	myeloid cell development	13/2112	70/18670	0.04859	0.1556	0.1124	FLI1/MEIS1/TLR2/EVI2B/PTPN6/NCKAP1L/PTPN11/TRIM58/PIP4K2A/SH2B3/WASF2/PTBP3/LILRB1	13
BP	GO:0030336	negative regulation of cell migration	48/2112	334/18670	0.04862	0.1556	0.1124	CXCL13/SLAMF8/SFRP1/IGFBP5/IL27RA/LIMCH1/DLG5/ARHGDIB/ARPIN/SEMA3A/MCTP1/CD200/CD74/PFN2/ITGB1BP1/SULF1/BMPR1A/WASL/RECK/ADA/DAG1/DLC1/FGF2/GPR18/DCN/ADORA3/IDH2/CCL21/MAGI2/CX3CR1/PTN/C5orf30/RRAS/LDLRAD4/NOTCH1/KANK1/NBL1/MECP2/PTGER4/ADIPOQ/DPYSL3/ARHGAP4/PRKG1/MIIP/FOXO3/ABHD6/CCL2/SCAI	48
BP	GO:0008344	adult locomotory behavior	14/2112	77/18670	0.04879	0.1559	0.1126	UCHL1/ZIC1/TMOD1/PBX3/GLRB/OXR1/NPC1/ADAM22/ATP1A2/MECP2/HOXD10/SNCG/HIPK2/CHL1	14
BP	GO:0048678	response to axon injury	14/2112	77/18670	0.04879	0.1559	0.1126	JAM3/JAK2/DAG1/CDK1/KCNK2/SCARF1/PTPRF/PTN/SOD1/PTPRS/DPYSL3/MAP1B/LYN/TXN2	14
BP	GO:0090596	sensory organ morphogenesis	38/2112	256/18670	0.04879	0.1559	0.1126	BMP4/LRP6/ZIC1/SOX9/GLI3/NTRK2/TSKU/SKI/CDON/MEIS1/SIX1/SIX2/GATA2/COL8A2/SOBP/COL8A1/BAK1/EPHB1/PTN/LRP5/SOD1/EFEMP1/RBP4/IRX5/TFAP2A/FGF9/NIPBL/FZD6/ZHX2/HIPK2/DIO3/DVL1/MYO3A/ROM1/ABI2/FZD2/CRYGB/AHI1	38
BP	GO:0140013	meiotic nuclear division	27/2112	172/18670	0.04898	0.1564	0.113	ASPM/PTTG1/PTTG3P/BUB1/GOLGA2/PLK1/UBE2B/NCAPH/CDC25B/BUB1B/DAZL/TOP2A/MYBL1/RMI1/CKS2/STAG3/TERF1/FBXO5/REC8/TTK/CDC20/SMC4/ACTR3/TRIP13/CCNE2/AURKA/ACTR2	27
BP	GO:0034329	cell junction assembly	36/2112	241/18670	0.04992	0.1589	0.1148	SFRP1/EPHA3/LIMCH1/PRKCH/DLG5/CDH19/PARD3/ANK2/ITGB1BP1/FERMT2/TNS1/DLC1/CDH2/EFNA5/SMAD3/VASP/CORO2B/CD9/MYOC/ECT2/PECAM1/PPM1F/MYO1C/TRIP6/SORBS1/CTTN/RHOD/CAPZA1/MPP5/KDR/GJC1/WDR1/LIMS2/COL16A1/NPHP4/CDH5	36
BP	GO:0043200	response to amino acid	19/2112	113/18670	0.04994	0.1589	0.1148	CDO1/NTRK2/GLRB/SIX1/ICAM1/PDGFD/SOCS1/EGFR/CPEB1/PCK1/PTN/DNMT1/BCL11A/CFL1/CYBA/SESN1/LYN/ALAD/COL16A1	19
BP	GO:0000725	recombinational repair	22/2112	135/18670	0.04995	0.1589	0.1148	NUCKS1/ZNF365/CDC45/BLM/WAS/MCM5/REV3L/PPP4C/RNF138/FEN1/RMI1/TIMELESS/CDC7/MCM2/PARP1/NIPBL/REC8/MORF4L1/MCM4/RAD51AP1/SMCHD1/ACTR2	22
BP	GO:0016311	dephosphorylation	66/2112	478/18670	0.05019	0.1589	0.1148	LCK/PTPRC/PPP1R3C/PTPN14/NT5E/EYA4/LILRB2/PTPRE/SEMA4D/HDDC2/PPP2CA/PPP3CA/DUSP5/PTPN2/EYA2/PTPRD/CILP/JAK2/PTPN7/CDC14B/PTPN6/DLC1/CDC25B/RPAP2/PHACTR2/PLEK/DLGAP5/MAGI2/ACP2/MTMR14/PPP1R16B/PTPRF/PTN/NCKAP1L/PPP4C/PPP2CB/PTPRS/INPP1/SMAD3/PTPN11/PTPN13/MFHAS1/PSPH/IFNG/PPP1CA/RGN/PPM1F/ALPL/HSP90AB1/PHLPP1/PINK1/PTPN22/DUSP6/INPP5D/SSH3/DUSP2/RPRD1A/ENSA/PPP1R11/DAPP1/CAMTA1/MTMR2/UBASH3A/EPHX2/CDH5/BPNT1	66
BP	GO:0007389	pattern specification process	62/2112	446/18670	0.0503	0.1589	0.1148	SFRP1/BMP4/LRP6/ZIC1/GALNT11/DYNC2LI1/HOXC10/HOXA10/ZBTB16/PBX3/GLI3/FOXC1/SEMA3A/SKI/CDON/AR/HOXC6/SIX1/BMPR1A/WLS/SIX2/COBL/MEOX1/KIF3B/BPTF/SMARCD3/ASPH/HOXC4/LRP5/TP63/PBX1/DCHS1/TCTN1/LEF1/SEMA3F/SMAD3/BHLHE41/DAAM2/NOTCH1/NBL1/MTF2/HEY2/HOXA4/ACVR1/HOXD10/TULP3/MEGF8/DDIT3/SCMH1/EMX2/HIPK2/HEY1/PKD2/NLE1/HOXA11/TP53/RFX4/FEZF2/AURKA/HOXA5/STIL/AHI1	62
BP	GO:0016331	morphogenesis of embryonic epithelium	24/2112	150/18670	0.05047	0.1589	0.1148	SFRP1/BMP4/LRP6/SOX9/SKI/AR/SULF1/SIX1/COBL/DLC1/SPINT2/TP63/TCTN1/VASP/TFAP2A/TULP3/APAF1/FZD6/CFL1/DVL1/KIF20B/FZD2/PFN1/STIL	24
BP	GO:0071774	response to fibroblast growth factor	24/2112	150/18670	0.05047	0.1589	0.1148	CCL5/CXCL13/SFRP1/RBFOX2/FGF18/FGF7/ITGB1BP1/SULF1/PRKD2/FGF2/CXCL8/HYAL1/PTPN11/KL/GTF2F1/KIF16B/ZFP36L1/POLR2L/FGF9/FAT4/SHCBP1/ZFP36L2/CCL2/RAB14	24
BP	GO:0010506	regulation of autophagy	47/2112	327/18670	0.05047	0.1589	0.1148	LAMP3/UCHL1/RAB8A/RASIP1/GOLGA2/PIP4K2B/HTR2B/RIPK2/DAP/DCN/NPC1/HGF/SNX5/TRIM21/FOXO1/PLK2/FBXL2/FEZ1/LEP/IFNG/PIK3CA/IL10RA/IKBKG/HSPB1/TRIM22/CTTN/PINK1/PTPN22/DDIT3/PIP4K2A/FOXO3/GFAP/PRKD1/SESN1/NOD1/EPM2A/KDR/FEZ2/FYCO1/WAC/USP10/TP53/BNIP3L/PRKAB1/ATP6V1B2/PIM2/DRAM1	47
BP	GO:0002087	regulation of respiratory gaseous exchange by neurological system process	4/2112	13/18670	0.05058	0.1589	0.1148	PBX3/NLGN1/ATP1A2/MECP2	4
BP	GO:0002430	complement receptor mediated signaling pathway	4/2112	13/18670	0.05058	0.1589	0.1148	CR1/FPR1/FPR2/CR2	4
BP	GO:0007183	SMAD protein complex assembly	4/2112	13/18670	0.05058	0.1589	0.1148	PMEPA1/SMAD3/LDLRAD4/PARP1	4
BP	GO:0010763	positive regulation of fibroblast migration	4/2112	13/18670	0.05058	0.1589	0.1148	DDR2/AKAP12/SLC8A1/PAK1	4
BP	GO:0010870	positive regulation of receptor biosynthetic process	4/2112	13/18670	0.05058	0.1589	0.1148	JAK2/IFNG/NR1H3/HOXA5	4
BP	GO:0014745	negative regulation of muscle adaptation	4/2112	13/18670	0.05058	0.1589	0.1148	IGFBP5/FOXO1/SMAD3/LMNA	4
BP	GO:0019896	axonal transport of mitochondrion	4/2112	13/18670	0.05058	0.1589	0.1148	UCHL1/TRAK2/FEZ1/SYBU	4
BP	GO:0032823	regulation of natural killer cell differentiation	4/2112	13/18670	0.05058	0.1589	0.1148	RASGRP1/IL15/AXL/TOX	4
BP	GO:0033127	regulation of histone phosphorylation	4/2112	13/18670	0.05058	0.1589	0.1148	UBE2B/RPS6KA4/CCNB1/IL1B	4
BP	GO:0035589	G protein-coupled purinergic nucleotide receptor signaling pathway	4/2112	13/18670	0.05058	0.1589	0.1148	GPR171/P2RY6/P2RY14/P2RY4	4
BP	GO:0035723	interleukin-15-mediated signaling pathway	4/2112	13/18670	0.05058	0.1589	0.1148	IL2RG/IL15RA/IL2RB/IL15	4
BP	GO:0042178	xenobiotic catabolic process	4/2112	13/18670	0.05058	0.1589	0.1148	GSTM5/GSTM3/GSTO1/GSTM2	4
BP	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein	4/2112	13/18670	0.05058	0.1589	0.1148	PPP2CA/PTPN2/SOCS1/SH2B3	4
BP	GO:0043301	negative regulation of leukocyte degranulation	4/2112	13/18670	0.05058	0.1589	0.1148	CCR2/HLA-F/LGALS9/IL13RA2	4
BP	GO:0048291	isotype switching to IgG isotypes	4/2112	13/18670	0.05058	0.1589	0.1148	PTPRC/IL27RA/CD40/TBX21	4
BP	GO:0050713	negative regulation of interleukin-1 beta secretion	4/2112	13/18670	0.05058	0.1589	0.1148	TNFAIP3/SERPINB1/PML/NLRP3	4
BP	GO:0060347	heart trabecula formation	4/2112	13/18670	0.05058	0.1589	0.1148	TGFBR3/RBP4/HEY2/HEY1	4
BP	GO:0060601	lateral sprouting from an epithelium	4/2112	13/18670	0.05058	0.1589	0.1148	BMP4/AR/SULF1/TP63	4
BP	GO:0071350	cellular response to interleukin-15	4/2112	13/18670	0.05058	0.1589	0.1148	IL2RG/IL15RA/IL2RB/IL15	4
BP	GO:0071415	cellular response to purine-containing compound	4/2112	13/18670	0.05058	0.1589	0.1148	SLC8A1/P2RY6/RYR3/GSTM2	4
BP	GO:0072044	collecting duct development	4/2112	13/18670	0.05058	0.1589	0.1148	BMP4/DLG5/AKR1B1/NOTCH1	4
BP	GO:0072182	regulation of nephron tubule epithelial cell differentiation	4/2112	13/18670	0.05058	0.1589	0.1148	STAT1/YAP1/WWTR1/FAT4	4
BP	GO:0072672	neutrophil extravasation	4/2112	13/18670	0.05058	0.1589	0.1148	ADAM8/PIK3CD/PECAM1/IL1R1	4
BP	GO:0098712	L-glutamate import across plasma membrane	4/2112	13/18670	0.05058	0.1589	0.1148	SLC1A3/PER2/ARL6IP5/ATP1A2	4
BP	GO:0045540	regulation of cholesterol biosynthetic process	10/2112	50/18670	0.05078	0.1593	0.1151	ABCG1/PMVK/ERLIN1/SP1/SOD1/ACACB/SC5D/NFYA/ERLIN2/MBTPS2	10
BP	GO:0086009	membrane repolarization	10/2112	50/18670	0.05078	0.1593	0.1151	CACNA2D1/ANK2/KCNJ5/KCNJ2/ATP1B1/SCN1B/KCNJ8/ATP1A2/WDR1/SNTA1	10
BP	GO:0106118	regulation of sterol biosynthetic process	10/2112	50/18670	0.05078	0.1593	0.1151	ABCG1/PMVK/ERLIN1/SP1/SOD1/ACACB/SC5D/NFYA/ERLIN2/MBTPS2	10
BP	GO:0044774	mitotic DNA integrity checkpoint	18/2112	106/18670	0.05094	0.1597	0.1154	TFDP2/BLM/E2F8/CDK1/TOP2A/PLK2/DONSON/CCNB1/CCND1/SYF2/NAE1/PRMT1/SETMAR/PCBP4/TP53/AURKA/TOPBP1/PML	18
BP	GO:0034404	nucleobase-containing small molecule biosynthetic process	34/2112	226/18670	0.05098	0.1597	0.1154	ENPP1/AMPD3/TYMP/IGF1/NT5E/ZBTB20/UPP1/ADK/SLC2A6/CBFA2T3/NUP93/HDAC4/HK3/NME7/ADA/ALDOC/PDE1A/TPR/ACAT1/NUP160/HTR2A/VCP/IFNG/ARNT/NUDT11/PNP/ENTPD4/NME4/NUP88/HINT1/TK2/NUP50/TK1/TP53	34
BP	GO:0048863	stem cell differentiation	38/2112	257/18670	0.05125	0.1605	0.116	PSMB9/KITLG/SFRP1/PTPRC/BMP4/PSMB8/LRP6/SEMA4A/PSMB10/SOX9/SEMA4D/BATF/LTBP3/FOXC1/SEMA3A/SOX5/BMPR1A/HTR2B/YAP1/GATA2/PSME1/MEOX1/KMT2A/PTN/TP63/FAM172A/SEMA3F/NOTCH1/MTF2/ACVR1/EDNRB/CFL1/SEMA4F/JARID2/SEMA3E/ZFP36L2/SEMA6B/TP53	38
BP	GO:0002714	positive regulation of B cell mediated immunity	8/2112	37/18670	0.05143	0.1608	0.1162	XCL1/PTPRC/CD40/TFRC/HLA-E/CD226/TBX21/BTK	8
BP	GO:0002891	positive regulation of immunoglobulin mediated immune response	8/2112	37/18670	0.05143	0.1608	0.1162	XCL1/PTPRC/CD40/TFRC/HLA-E/CD226/TBX21/BTK	8
BP	GO:0006270	DNA replication initiation	8/2112	37/18670	0.05143	0.1608	0.1162	PURA/CDC45/MCM5/MCM2/POLE2/MCM4/CCNE2/MCM10	8
BP	GO:1903514	release of sequestered calcium ion into cytosol by endoplasmic reticulum	8/2112	37/18670	0.05143	0.1608	0.1162	CCR5/SRI/ANK2/PLN/ATP1A2/SLC8A1/GSTO1/GSTM2	8
BP	GO:0001708	cell fate specification	17/2112	99/18670	0.05183	0.1617	0.1169	HOXC10/SOX9/GLI3/CDON/AR/EYA2/SIX1/BMPR1A/SIX2/FGF2/TBX21/SOX2/FZD7/NOTCH1/HOXD10/TENM4/HOXA11	17
BP	GO:0019395	fatty acid oxidation	17/2112	99/18670	0.05183	0.1617	0.1169	ALDH3A2/ACADVL/ACOX2/ECHDC2/ACAT1/ETFB/ACACB/LEP/BDH2/ECI2/ADIPOQ/PDK4/ECI1/ACADL/HADH/ECHS1/HADHA	17
BP	GO:0070301	cellular response to hydrogen peroxide	17/2112	99/18670	0.05183	0.1617	0.1169	PLEKHA1/TNFAIP3/NQO1/AXL/SIGMAR1/PDGFD/SPHK1/CDK1/HGF/EZH2/MAPK13/FOXO1/NET1/ECT2/PINK1/IL6/FOXO3	17
BP	GO:0031346	positive regulation of cell projection organization	54/2112	383/18670	0.05184	0.1617	0.1169	NDNF/EPHA3/S100A9/DLG5/RAC2/CXCR4/CCL19/SEMA4D/NTRK2/CCR7/LPAR1/AUTS2/PTPRD/HDAC4/ITSN1/COBL/WASL/SHOX2/TUBB2B/DZIP1/TRPV2/CCL21/CREB3L2/CDC42EP3/HGF/MAGI2/NLGN1/EZH2/CEP135/SCARF1/CAMK1D/PTN/FZD4/EFNA5/SCN1B/FEZ1/GDI1/SERPINI1/FNBP1L/SYT17/PAK1/DPYSL3/TGFB3/SCARB2/CHODL/MAP1B/MEGF8/PRKD1/LYN/DVL1/WASF2/CFLAR/PFN1/ACTR2	54
BP	GO:0045981	positive regulation of nucleotide metabolic process	11/2112	57/18670	0.05235	0.163	0.1178	PID1/IGF1/ZBTB20/CDK1/HTR2A/VCP/IFNG/ARNT/CCNB1/PINK1/GUCA1A	11
BP	GO:0051055	negative regulation of lipid biosynthetic process	11/2112	57/18670	0.05235	0.163	0.1178	AKR1C3/ACADVL/SPHK1/SIK1/ERLIN1/SOD1/NFKB1/ERLIN2/GFI1/ACADL/DKK3	11
BP	GO:1900544	positive regulation of purine nucleotide metabolic process	11/2112	57/18670	0.05235	0.163	0.1178	PID1/IGF1/ZBTB20/CDK1/HTR2A/VCP/IFNG/ARNT/CCNB1/PINK1/GUCA1A	11
BP	GO:0098742	cell-cell adhesion via plasma-membrane adhesion molecules	40/2112	273/18670	0.05236	0.163	0.1178	PCDH9/PCDHB3/CDH19/ITGB2/PTPRD/ICAM1/SELL/ANXA3/PCDHB13/ITGAL/PCDHB11/SELE/NLGN1/PCDHGA3/CLSTN1/PTPRF/PCDH17/CDH2/CADM1/DCHS1/PTPRS/CD6/EFNA5/CEACAM5/PCDHGC3/DSC2/PECAM1/ADIPOQ/ACVR1/GPC4/FAT4/PCDHGA9/IL1RN/MPZL2/CD164/TENM4/PCDHB6/CLDN14/PCDHB12/CDH5	40
BP	GO:0030968	endoplasmic reticulum unfolded protein response	20/2112	121/18670	0.05258	0.1636	0.1182	PIK3R1/ACADVL/PTPN2/EXTL2/CXCL8/SEC31A/CREB3L2/BAK1/TSPYL2/EDEM1/KDELR3/VCP/GFPT1/FKBP14/CCND1/DDIT3/LMNA/MBTPS2/TATDN2/CCL2	20
BP	GO:0034308	primary alcohol metabolic process	15/2112	85/18670	0.05317	0.1653	0.1194	IGF1/ALDH3A2/AKR1C3/ADH1C/AKR1B1/DHRS3/AKR1C1/RBP4/ADH1B/ADH5/DHRS9/RETSAT/NAAA/DKK3/AKR7A2	15
BP	GO:0045682	regulation of epidermis development	15/2112	85/18670	0.05317	0.1653	0.1194	BMP4/PRKCH/FOXC1/CTSL/KLF7/EZH2/TP63/NOTCH1/ZFP36L1/HEY2/FST/FERMT1/SPINK5/KRT10/MYCL	15
BP	GO:0044783	G1 DNA damage checkpoint	12/2112	64/18670	0.05322	0.1654	0.1195	TFDP2/E2F8/CDK1/PLK2/CCNB1/CCND1/PRMT1/PCBP4/WAC/TP53/AURKA/PML	12
BP	GO:0043407	negative regulation of MAP kinase activity	14/2112	78/18670	0.05352	0.1662	0.1201	SFRP1/BMP4/UCHL1/PPP2CA/DUSP5/PTPN6/ADIPOQ/MBIP/PTPN22/DUSP6/DUSP2/LYN/SH2B3/IL1B	14
BP	GO:0006936	muscle contraction	51/2112	360/18670	0.05354	0.1662	0.1201	SSPN/PLCE1/CXCR4/SYNM/TMOD1/SRI/CACNA2D1/ANK2/SGCA/SULF1/FXYD1/CRYAB/DYSF/HDAC4/COMP/HTR2B/ADA/KCNJ5/SPHK1/CALD1/PLN/ASPH/SOD1/SGCD/KCNJ2/HTR2A/ATP1B1/SCN1B/KCNJ8/DSC2/LMOD1/ATP1A2/PIK3CA/MYL5/SLC8A1/EDNRB/SORBS1/CTTN/CD38/PRKG1/MYH11/HSPB6/MYL9/VEGFB/GSTO1/MYLK/GJC1/GSTM2/MYL6B/SNTA1/GPD1L	51
BP	GO:0071479	cellular response to ionizing radiation	13/2112	71/18670	0.05357	0.1662	0.1201	SFRP1/NUCKS1/CRYAB/YAP1/BLM/NOX4/NET1/ECT2/NIPBL/CYBA/RAD51AP1/TP53/GTF2H5	13
BP	GO:0042752	regulation of circadian rhythm	19/2112	114/18670	0.05383	0.1668	0.1206	ZFHX3/ADA/OPN3/CDK1/SIK1/NLGN1/EZH2/PER2/TOP2A/ARNTL/TIMELESS/PPP1CA/PHLPP1/PER3/NR1H3/TP53/USP7/KDM2A/PML	19
BP	GO:0002082	regulation of oxidative phosphorylation	7/2112	31/18670	0.05413	0.1668	0.1206	COX7A1/CDK1/VCP/CCNB1/SLC25A23/PINK1/COX7A2	7
BP	GO:0003299	muscle hypertrophy in response to stress	7/2112	31/18670	0.05413	0.1668	0.1206	PPP3CA/HDAC4/EZH2/FOXO1/SMAD3/HEY2/LMNA	7
BP	GO:0003401	axis elongation	7/2112	31/18670	0.05413	0.1668	0.1206	SFRP1/BMP4/LRP6/SOX9/SIX1/YAP1/MAGI2	7
BP	GO:0006506	GPI anchor biosynthetic process	7/2112	31/18670	0.05413	0.1668	0.1206	PIGK/DPM3/GPAA1/PIGH/PIGP/PIGT/PIGF	7
BP	GO:0009954	proximal/distal pattern formation	7/2112	31/18670	0.05413	0.1668	0.1206	HOXC10/HOXA10/GLI3/TP63/PBX1/HOXD10/HOXA11	7
BP	GO:0010165	response to X-ray	7/2112	31/18670	0.05413	0.1668	0.1206	SFRP1/NUCKS1/BLM/CCND1/NIPBL/ERCC1/TP53	7
BP	GO:0014887	cardiac muscle adaptation	7/2112	31/18670	0.05413	0.1668	0.1206	PPP3CA/HDAC4/EZH2/FOXO1/SMAD3/HEY2/LMNA	7
BP	GO:0014898	cardiac muscle hypertrophy in response to stress	7/2112	31/18670	0.05413	0.1668	0.1206	PPP3CA/HDAC4/EZH2/FOXO1/SMAD3/HEY2/LMNA	7
BP	GO:0031572	G2 DNA damage checkpoint	7/2112	31/18670	0.05413	0.1668	0.1206	DTL/PLK1/CDC14B/BLM/CDK1/DONSON/SYF2	7
BP	GO:0045879	negative regulation of smoothened signaling pathway	7/2112	31/18670	0.05413	0.1668	0.1206	ENPP1/CD3E/GLI3/TULP3/MEGF8/RB1/RFX4	7
BP	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	7/2112	31/18670	0.05413	0.1668	0.1206	LPAR1/GPR18/GPR65/AGTR1/S1PR1/TGM2/GPR4	7
BP	GO:0099625	ventricular cardiac muscle cell membrane repolarization	7/2112	31/18670	0.05413	0.1668	0.1206	CACNA2D1/ANK2/KCNJ5/SCN1B/KCNJ8/WDR1/SNTA1	7
BP	GO:0003197	endocardial cushion development	9/2112	44/18670	0.05486	0.1688	0.1219	BMP4/SOX9/BMPR1A/TMEM100/DCHS1/NOTCH1/HEY2/ACVR1/HEY1	9
BP	GO:0034105	positive regulation of tissue remodeling	9/2112	44/18670	0.05486	0.1688	0.1219	IL15/LTBP3/PPP3CA/ADAM8/TFRC/EGFR/CA2/SYK/IL18	9
BP	GO:0038084	vascular endothelial growth factor signaling pathway	9/2112	44/18670	0.05486	0.1688	0.1219	FOXC1/PRKD2/DCN/FLT3/MYO1C/HSPB1/VEGFB/PRKD1/KDR	9
BP	GO:0044060	regulation of endocrine process	9/2112	44/18670	0.05486	0.1688	0.1219	INHBA/TAC1/PTPN11/LEP/AGTR1/OR51E2/REN/IL1B/RAB11FIP1	9
BP	GO:0030330	DNA damage response, signal transduction by p53 class mediator	18/2112	107/18670	0.05503	0.1688	0.122	TFDP2/BATF/CD74/E2F8/CDK1/PMAIP1/ATRX/PLK2/CCNB1/SMYD2/FOXO3/HIPK2/PRMT1/PCBP4/USP10/TP53/AURKA/PML	18
BP	GO:0043502	regulation of muscle adaptation	18/2112	107/18670	0.05503	0.1688	0.122	IGFBP5/IGF1/TNFRSF1B/PPP3CA/SGCA/HDAC4/DAG1/GTF2IRD2B/FOXO1/SMAD3/NOTCH1/IL6ST/GTF2IRD1/PAK1/PARP1/JARID2/FOXO3/LMNA	18
BP	GO:0001710	mesodermal cell fate commitment	5/2112	19/18670	0.05543	0.1688	0.122	BMP4/EYA2/BMPR1A/SIX2/HOXA11	5
BP	GO:0002076	osteoblast development	5/2112	19/18670	0.05543	0.1688	0.122	PTHLH/HDAC4/LRP5/SMAD3/PTH1R	5
BP	GO:0003159	morphogenesis of an endothelium	5/2112	19/18670	0.05543	0.1688	0.122	BMP4/CXCR4/PRKD2/CXCL10/ITGAX	5
BP	GO:0032011	ARF protein signal transduction	5/2112	19/18670	0.05543	0.1688	0.122	CYTH1/MAPRE2/PSD3/CYTH4/PSD4	5
BP	GO:0032012	regulation of ARF protein signal transduction	5/2112	19/18670	0.05543	0.1688	0.122	CYTH1/MAPRE2/PSD3/CYTH4/PSD4	5
BP	GO:0034138	toll-like receptor 3 signaling pathway	5/2112	19/18670	0.05543	0.1688	0.122	TNFAIP3/RFTN1/TNIP2/COLEC12/PTPN22	5
BP	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process	5/2112	19/18670	0.05543	0.1688	0.122	HSD17B12/ELOVL4/ELOVL2/ACSL5/ELOVL5	5
BP	GO:0048486	parasympathetic nervous system development	5/2112	19/18670	0.05543	0.1688	0.122	SEMA3A/SIX1/SEMA3F/NAV2/TFAP2A	5
BP	GO:0060252	positive regulation of glial cell proliferation	5/2112	19/18670	0.05543	0.1688	0.122	PRKCH/ETV5/IL6/LYN/IL1B	5
BP	GO:0060438	trachea development	5/2112	19/18670	0.05543	0.1688	0.122	BMP4/LRP6/SOX9/LEF1/HOXA5	5
BP	GO:0061154	endothelial tube morphogenesis	5/2112	19/18670	0.05543	0.1688	0.122	BMP4/CXCR4/PRKD2/CXCL10/ITGAX	5
BP	GO:0071731	response to nitric oxide	5/2112	19/18670	0.05543	0.1688	0.122	CCL19/CCR7/CCNA2/FOXO1/CFLAR	5
BP	GO:0072074	kidney mesenchyme development	5/2112	19/18670	0.05543	0.1688	0.122	BMP4/STAT1/SIX1/SIX2/PKD2	5
BP	GO:0072576	liver morphogenesis	5/2112	19/18670	0.05543	0.1688	0.122	TNFAIP3/RPS6KA1/PTN/CFLAR/LIMS2	5
BP	GO:0090201	negative regulation of release of cytochrome c from mitochondria	5/2112	19/18670	0.05543	0.1688	0.122	IGF1/CLU/HGF/HIGD1A/LMNA	5
BP	GO:0098581	detection of external biotic stimulus	5/2112	19/18670	0.05543	0.1688	0.122	TLR2/NOD2/CLEC7A/NOD1/TLR6	5
BP	GO:1902644	tertiary alcohol metabolic process	5/2112	19/18670	0.05543	0.1688	0.122	AKR1C3/AKR1B1/AKR1C1/DKK3/AKR7A2	5
BP	GO:2000696	regulation of epithelial cell differentiation involved in kidney development	5/2112	19/18670	0.05543	0.1688	0.122	STAT1/YAP1/ADIPOQ/WWTR1/FAT4	5
BP	GO:0051650	establishment of vesicle localization	42/2112	290/18670	0.05576	0.1693	0.1223	SERPINA1/RASGRP1/MREG/ITGA4/PREPL/PRKCB/PFN2/LRMP/CTSC/GOLGA2/TRAK2/WASL/DNM1/F5/KIF3B/SEC31A/NLGN1/TMEM230/DYNC1I1/HTR2A/CHRNA5/RAB27A/FNBP1L/SYT17/MYO1C/STX4/ANKRD28/IKBKG/VAMP2/STXBP1/PINK1/BACE1/SYBU/AP1AR/DVL1/FYCO1/CNIH1/CASK/KIF1B/P2RY4/CADPS/KIF23	42
BP	GO:0003071	renal system process involved in regulation of systemic arterial blood pressure	6/2112	25/18670	0.05583	0.1693	0.1223	EMP2/CORO2B/AGTR1/OR51E2/CYBA/REN	6
BP	GO:0009648	photoperiodism	6/2112	25/18670	0.05583	0.1693	0.1223	SIK1/PER2/PPP1CA/PER3/TP53/PML	6
BP	GO:0019430	removal of superoxide radicals	6/2112	25/18670	0.05583	0.1693	0.1223	GCH1/NQO1/CD36/FBLN5/SOD1/RGN	6
BP	GO:0032461	positive regulation of protein oligomerization	6/2112	25/18670	0.05583	0.1693	0.1223	AIM2/CLU/MMP1/BID/PMAIP1/TP53	6
BP	GO:0032616	interleukin-13 production	6/2112	25/18670	0.05583	0.1693	0.1223	IRF4/LGALS9/HLA-E/LEF1/IL18/NLRP3	6
BP	GO:0060571	morphogenesis of an epithelial fold	6/2112	25/18670	0.05583	0.1693	0.1223	BMP4/AR/SULF1/EGFR/TP63/CFL1	6
BP	GO:0071378	cellular response to growth hormone stimulus	6/2112	25/18670	0.05583	0.1693	0.1223	PIK3R1/JAK2/GHR/SOCS2/PRL/LYN	6
BP	GO:2000104	negative regulation of DNA-dependent DNA replication	6/2112	25/18670	0.05583	0.1693	0.1223	BLM/STAG2/DONSON/TIMELESS/TERF1/FBXO5	6
BP	GO:0120034	positive regulation of plasma membrane bounded cell projection assembly	17/2112	100/18670	0.05614	0.1701	0.1229	RAC2/CCL19/CCR7/AUTS2/HDAC4/COBL/WASL/DZIP1/CCL21/CDC42EP3/NLGN1/CEP135/FNBP1L/DPYSL3/TGFB3/WASF2/PFN1	17
BP	GO:0090257	regulation of muscle system process	38/2112	259/18670	0.05642	0.1709	0.1235	IGFBP5/IGF1/TNFRSF1B/PLCE1/SRI/ANK2/PPP3CA/SGCA/HDAC4/ADA/DAG1/SPHK1/FGF13/GTF2IRD2B/PLN/SOD1/KCNJ2/ATP1B1/FOXO1/SMAD3/NOTCH1/IL6ST/GTF2IRD1/DSC2/ATP1A2/MYL5/SLC8A1/PAK1/PARP1/CTTN/PRKG1/JARID2/FOXO3/LMNA/HSPB6/MYL9/GSTO1/GSTM2	38
BP	GO:0019730	antimicrobial humoral response	20/2112	122/18670	0.05647	0.171	0.1235	CXCL13/CXCL9/S100A9/CLU/SLPI/CCL13/GNLY/CXCL1/LYZ/CXCL10/HLA-E/CXCL8/IGHM/CXCL3/CXCL11/KRT6A/CXCL2/CXCL5/CXCL6/SPINK5	20
BP	GO:0010821	regulation of mitochondrion organization	28/2112	182/18670	0.05654	0.1711	0.1236	PID1/TFDP2/IGF1/CLU/RAC2/GZMB/BID/TNFSF10/TMEM14A/DCN/BAK1/HGF/TP63/PMAIP1/FAM162A/HIGD1A/TMEM135/CTTN/PINK1/LMNA/SLC25A5/KDR/HSPA1L/TP53BP2/TP53/BNIP3L/MOAP1/INF2	28
BP	GO:0006213	pyrimidine nucleoside metabolic process	10/2112	51/18670	0.05703	0.1724	0.1246	TYMP/NT5E/UPP1/APOBEC3G/APOBEC3B/NME7/ENTPD4/NME4/TK2/TK1	10
BP	GO:0050999	regulation of nitric-oxide synthase activity	10/2112	51/18670	0.05703	0.1724	0.1246	GCH1/WASL/HTR2B/EGFR/DDAH2/LEP/GLA/NOD1/NPR3/IL1B	10
BP	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	16/2112	93/18670	0.05713	0.1726	0.1247	PSMB9/PSMB8/PSMB10/SKP1/PSME1/BLM/FHL1/CDK1/DONSON/MIIP/AURKB/FBXL7/SYF2/NAE1/AURKA/TOPBP1	16
BP	GO:0060048	cardiac muscle contraction	22/2112	137/18670	0.05718	0.1727	0.1248	CXCR4/SRI/CACNA2D1/ANK2/HDAC4/KCNJ5/PLN/SGCD/KCNJ2/ATP1B1/SCN1B/KCNJ8/DSC2/ATP1A2/PIK3CA/SLC8A1/VEGFB/GSTO1/GJC1/GSTM2/SNTA1/GPD1L	22
BP	GO:0030902	hindbrain development	24/2112	152/18670	0.05734	0.1731	0.1251	CD3E/LRP6/RBFOX2/MYH10/FOXC1/LPAR1/ZNF365/WLS/GATA2/DLC1/NFIB/EZH2/PTN/PTPRS/FZD4/LEF1/PTPN11/MECP2/PAK1/SDF4/CLP1/TP53/B4GALT2/AHI1	24
BP	GO:0043270	positive regulation of ion transport	40/2112	275/18670	0.05746	0.1734	0.1253	CCL5/CXCL9/XCL1/CCR2/SRI/CACNA2D1/ANK2/FXYD1/CXCL10/ATP8A1/FHL1/TRPV2/PLCG2/BAK1/AHCYL1/CCR1/KCNJ2/TRPC1/CD19/ATP1B1/SCN1B/LEP/IFNG/KMO/RGN/CXCL11/FGF14/P2RY6/APLNR/STXBP1/PINK1/TESC/PKD2/GSTO1/MYLK/GSTM2/CCL2/CASK/IL1B/GPD1L	40
BP	GO:0048013	ephrin receptor signaling pathway	15/2112	86/18670	0.05795	0.1748	0.1263	EPHA3/ITSN1/WASL/DNM1/EPHB1/EFNA5/PTPN11/CHN1/PAK1/LYN/ARPC1A/ACTR3/SS18/VAV3/ACTR2	15
BP	GO:0017001	antibiotic catabolic process	11/2112	58/18670	0.05827	0.1752	0.1266	AKR1C3/HBB/ESD/PCK1/GPX3/NAGK/HBD/PRDX6/ADH5/HP/CAT	11
BP	GO:0030837	negative regulation of actin filament polymerization	11/2112	58/18670	0.05827	0.1752	0.1266	ADD3/TMOD1/PFN2/TMSB10/KANK1/LMOD1/CAPZA1/VILL/PFN1/SPTBN1/GSN	11
BP	GO:0032722	positive regulation of chemokine production	11/2112	58/18670	0.05827	0.1752	0.1266	TLR2/CD74/IL4R/LGALS9/RIPK2/CLEC7A/IFNG/ADIPOQ/SYK/IL6/IL1B	11
BP	GO:0046605	regulation of centrosome cycle	11/2112	58/18670	0.05827	0.1752	0.1266	KIF11/MAP9/MCPH1/NEK2/PLK2/CEP85/CHMP2B/CCNF/AURKA/CHMP1B/STIL	11
BP	GO:0051058	negative regulation of small GTPase mediated signal transduction	11/2112	58/18670	0.05827	0.1752	0.1266	ARHGAP25/RASIP1/TIMP2/DLC1/PPP2CB/TNFAIP1/RASA2/MYOC/KANK1/ARHGAP12/SCAI	11
BP	GO:0060997	dendritic spine morphogenesis	11/2112	58/18670	0.05827	0.1752	0.1266	DOCK10/ZNF365/WASL/NLGN1/EPHB1/PDLIM5/CFL1/ADAM10/DVL1/ABI2/ACTR2	11
BP	GO:0071385	cellular response to glucocorticoid stimulus	11/2112	58/18670	0.05827	0.1752	0.1266	ICAM1/EGFR/PCK1/FOXO1/ZFP36L1/SSTR5/FLT3/AKAP13/FOXO3/CFLAR/ZFP36L2	11
BP	GO:0006110	regulation of glycolytic process	14/2112	79/18670	0.05857	0.176	0.1271	IGF1/ZBTB20/SLC2A6/CBFA2T3/NUP93/HDAC4/TPR/NUP160/HTR2A/IFNG/ARNT/NUP88/NUP50/TP53	14
BP	GO:0031060	regulation of histone methylation	12/2112	65/18670	0.05884	0.1764	0.1275	AUTS2/KMT2A/DNMT1/ATRX/BRD4/PAX5/MECP2/MTF2/GFI1/PAF1/JARID2/LMNA	12
BP	GO:0060389	pathway-restricted SMAD protein phosphorylation	12/2112	65/18670	0.05884	0.1764	0.1275	GDF5/BMP4/INHBA/BMPR1A/TWSG1/TGFBR3/PMEPA1/LDLRAD4/ACVR1/HFE/TGFB3/TTK	12
BP	GO:0070192	chromosome organization involved in meiotic cell cycle	12/2112	65/18670	0.05884	0.1764	0.1275	BUB1/NCAPD2/UBE2B/NCAPH/BUB1B/ATRX/STAG3/TERF1/REC8/SMC4/TRIP13/CCNE2	12
BP	GO:0006084	acetyl-CoA metabolic process	8/2112	38/18670	0.05895	0.1764	0.1275	KYNU/PMVK/MPC2/ACAT1/ACACB/PDK4/MPC1/AASS	8
BP	GO:0032350	regulation of hormone metabolic process	8/2112	38/18670	0.05895	0.1764	0.1275	AKR1C3/TCF7L2/NFKB1/IFNG/ARNT/GFI1/DKK3/IL1B	8
BP	GO:0048009	insulin-like growth factor receptor signaling pathway	8/2112	38/18670	0.05895	0.1764	0.1275	PIK3R1/IGFBP5/IGF1/IGFBP6/AR/CILP/GHR/IGFBP2	8
BP	GO:1902742	apoptotic process involved in development	8/2112	38/18670	0.05895	0.1764	0.1275	TNFRSF1B/FOXC1/CRYAB/BAK1/ZPR1/LEF1/NOTCH1/SPI1	8
BP	GO:1905898	positive regulation of response to endoplasmic reticulum stress	8/2112	38/18670	0.05895	0.1764	0.1275	PIK3R1/SERINC3/PTPN2/BAK1/PMAIP1/EDEM1/DDIT3/EDEM2	8
BP	GO:0046661	male sex differentiation	25/2112	160/18670	0.05903	0.1766	0.1276	KITLG/PLEKHA1/SFRP1/ASPM/HOXA10/SOX9/SEMA3A/INHBA/AKR1C3/RHOBTB3/TNFSF10/AR/ZFPM2/SGPL1/ICAM1/BMPR1A/BCL2L2/ATRX/CCND1/FGF9/REC8/FSTL3/REN/ERCC1/HOXA11	25
BP	GO:0072659	protein localization to plasma membrane	38/2112	260/18670	0.05915	0.1769	0.1278	PID1/PIK3R1/EPHA3/GBP1/LRP6/PRKCH/CSK/PREPL/RAB8A/ANK2/EMP2/ITGB1BP1/GAK/AR/EGFR/FGF13/CDH2/DCHS1/SKAP1/ATP1B1/RHOG/IFNG/ADIPOQ/STX4/BBS1/SORBS1/VAMP2/TSPAN14/STXBP1/TESC/CLIP3/MPP5/CD81/GOLGA7/VTI1B/RAB11FIP2/SPTBN1/PRKG2	38
BP	GO:0006821	chloride transport	18/2112	108/18670	0.05935	0.1772	0.128	APOL1/PCYOX1/GLRB/FXYD1/SLC26A2/CLCN4/SLC1A3/CA2/SLC12A2/P2RY6/SLC12A8/CLIC5/SLC12A7/CLCN7/CLCN5/CLCC1/P2RY4/PRKG2	18
BP	GO:0009062	fatty acid catabolic process	18/2112	108/18670	0.05935	0.1772	0.128	ALDH3A2/ACADVL/ACOX2/ECHDC2/ACAT1/PCK1/ETFB/ACACB/PCCA/LEP/BDH2/ECI2/ADIPOQ/ECI1/ACADL/HADH/ECHS1/HADHA	18
BP	GO:0046916	cellular transition metal ion homeostasis	18/2112	108/18670	0.05935	0.1772	0.128	LCK/S100A9/SCO2/SRI/SKP1/SLC22A17/CYBRD1/CP/TFRC/SLC31A2/SLC39A8/SOD1/PRND/HFE/SLC39A6/NDFIP1/SLC39A7/MT1X	18
BP	GO:0071478	cellular response to radiation	29/2112	191/18670	0.06103	0.1821	0.1316	PIK3R1/SFRP1/NUCKS1/MFAP4/CRYAB/YAP1/BLM/CREBBP/OPN3/BAK1/ADIRF/PTN/NOX4/MAPK13/NET1/HYAL1/ECT2/PARP1/NIPBL/AURKB/CYBA/GUCA1A/METAP2/CUL4B/RAD51AP1/ERCC1/PBK/TP53/GTF2H5	29
BP	GO:0032570	response to progesterone	9/2112	45/18670	0.06199	0.1848	0.1335	TLR2/YAP1/PTN/CSN1S1/FOSL1/TGFB3/CD38/TYMS/NR1H3	9
BP	GO:1902743	regulation of lamellipodium organization	9/2112	45/18670	0.06199	0.1848	0.1335	RAC2/ARPIN/AUTS2/HDAC4/PDPN/WAS/KANK1/FER/WASF2	9
BP	GO:0002220	innate immune response activating cell surface receptor signaling pathway	19/2112	116/18670	0.06225	0.1852	0.1338	PSMB9/RELB/PSMB8/CLEC10A/FCN1/PSMB10/SKP1/MALT1/PSME1/CREBBP/PLCG2/CLEC4E/NFKB1/ICAM3/CLEC4A/PAK1/SYK/IKBKG/LYN	19
BP	GO:0007569	cell aging	19/2112	116/18670	0.06225	0.1852	0.1338	PRELP/HLA-G/ICAM1/BMPR1A/SMC6/CDK1/NOX4/TP63/SOD1/PLK2/ARNTL/FBXO5/AKT3/LMNA/RWDD1/HMGA1/ERCC1/TP53/PML	19
BP	GO:0034219	carbohydrate transmembrane transport	19/2112	116/18670	0.06225	0.1852	0.1338	ENPP1/PID1/PIK3R1/IGF1/SLC17A5/PRKCB/SLC2A6/SLC2A3/PTPN11/SLC2A10/LEP/SLC5A3/ADIPOQ/FABP5/SORBS1/CLIP3/SLC23A2/SLC2A5/IL1B	19
BP	GO:0070252	actin-mediated cell contraction	19/2112	116/18670	0.06225	0.1852	0.1338	TMOD1/SRI/CACNA2D1/ANK2/EMP2/PDPN/KCNJ5/PLN/PARVA/SGCD/KCNJ2/SCN1B/KCNJ8/DSC2/ATP1A2/GJC1/MYL6B/SNTA1/GPD1L	19
BP	GO:0006505	GPI anchor metabolic process	7/2112	32/18670	0.0628	0.1862	0.1346	PIGK/DPM3/GPAA1/PIGH/PIGP/PIGT/PIGF	7
BP	GO:0009261	ribonucleotide catabolic process	7/2112	32/18670	0.0628	0.1862	0.1346	AMPD3/NT5E/PDE1A/ACAT1/NUDT11/ENTPD4/HINT1	7
BP	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	7/2112	32/18670	0.0628	0.1862	0.1346	SRI/ANK2/PLN/ATP1A2/SLC8A1/GSTO1/GSTM2	7
BP	GO:0051085	chaperone cofactor-dependent protein refolding	7/2112	32/18670	0.0628	0.1862	0.1346	CD74/GAK/HSPA6/DNAJC7/HSPA1L/DNAJB4/ST13	7
BP	GO:0051385	response to mineralocorticoid	7/2112	32/18670	0.0628	0.1862	0.1346	CSN1S1/CCND1/FOSL1/PARP1/MAOB/FOXO3/CYBA	7
BP	GO:0061311	cell surface receptor signaling pathway involved in heart development	7/2112	32/18670	0.0628	0.1862	0.1346	BMP4/GALNT11/BMPR1A/NOTCH1/HEY2/ACVR1/HEY1	7
BP	GO:0061384	heart trabecula morphogenesis	7/2112	32/18670	0.0628	0.1862	0.1346	BMPR1A/TGFBR3/RBP4/NOTCH1/HEY2/HEY1/S1PR1	7
BP	GO:0055076	transition metal ion homeostasis	21/2112	131/18670	0.06296	0.1866	0.1348	LCK/S100A9/SCO2/SRI/SKP1/SLC22A17/CYBRD1/CP/TFRC/SLC31A2/CUTC/SLC39A8/NEO1/SOD1/BDH2/PRND/HFE/SLC39A6/NDFIP1/SLC39A7/MT1X	21
BP	GO:0006112	energy reserve metabolic process	15/2112	87/18670	0.06302	0.1867	0.1349	ENPP1/PID1/IGF1/PPP1R3C/PASK/PHKB/PER2/KL/GFPT1/LEP/IL6ST/PPP1CA/SORBS1/UGP2/GFPT2	15
BP	GO:2000045	regulation of G1/S transition of mitotic cell cycle	28/2112	184/18670	0.06327	0.1873	0.1354	CDKN2C/TFDP2/CCND2/BID/KANK2/PSME1/EGFR/BTN2A2/CDC45/PTPN6/E2F8/FHL1/CDK1/EZH2/HYAL1/PLK2/CCNB1/DACT1/CCND1/RB1/CUL4B/PKD2/PRMT1/PCBP4/TP53/CCL2/AURKA/PML	28
BP	GO:0030514	negative regulation of BMP signaling pathway	10/2112	52/18670	0.06376	0.1883	0.1361	SFRP1/SKI/HTRA1/TWSG1/NOTCH1/NBL1/TOB1/CHRDL1/HIPK2/FSTL3	10
BP	GO:0051438	regulation of ubiquitin-protein transferase activity	10/2112	52/18670	0.06376	0.1883	0.1361	UBE2C/MAD2L1/GOLGA2/PLK1/CDC14B/BAG2/FBXO5/PINK1/CDC20/BAG5	10
BP	GO:1900024	regulation of substrate adhesion-dependent cell spreading	10/2112	52/18670	0.06376	0.1883	0.1361	GBP1/ITGB1BP1/PDPN/DOCK1/EFNA5/MYOC/KANK1/AP1AR/FBLN1/LIMS2	10
BP	GO:2000677	regulation of transcription regulatory region DNA binding	10/2112	52/18670	0.06376	0.1883	0.1361	IGF1/SRI/FOXC1/PER2/IFNG/HEY2/PARP1/DDIT3/RB1/HEY1	10
BP	GO:0009988	cell-cell recognition	13/2112	73/18670	0.06455	0.1883	0.1361	PRF1/CCL19/CCR7/CCL21/EPHB1/CD6/DOCK2/CD9/HSPA1L/OVGP1/CD81/PCDHB6/UBAP2L	13
BP	GO:0072401	signal transduction involved in DNA integrity checkpoint	13/2112	73/18670	0.06455	0.1883	0.1361	TFDP2/DTL/PLK1/CDC14B/E2F8/CDK1/PLK2/CCNB1/PRMT1/PCBP4/TP53/AURKA/PML	13
BP	GO:0072422	signal transduction involved in DNA damage checkpoint	13/2112	73/18670	0.06455	0.1883	0.1361	TFDP2/DTL/PLK1/CDC14B/E2F8/CDK1/PLK2/CCNB1/PRMT1/PCBP4/TP53/AURKA/PML	13
BP	GO:1903779	regulation of cardiac conduction	13/2112	73/18670	0.06455	0.1883	0.1361	SRI/ANK2/NPR2/FXYD1/FXYD6/AHCYL1/ASPH/TRPC1/ATP1B1/ATP1A2/SLC8A1/RYR3/ATP2A3	13
BP	GO:0001658	branching involved in ureteric bud morphogenesis	11/2112	59/18670	0.06462	0.1883	0.1361	BMP4/SOX9/GLI3/SIX1/SIX2/FGF2/PBX1/DCHS1/FAT4/PKD2/HOXA11	11
BP	GO:0021885	forebrain cell migration	11/2112	59/18670	0.06462	0.1883	0.1361	CXCR4/GLI3/SEMA3A/AXL/EGFR/FGF13/DIXDC1/EMX2/POU3F3/FEZF2/MBOAT7	11
BP	GO:0007501	mesodermal cell fate specification	4/2112	14/18670	0.06467	0.1883	0.1361	EYA2/BMPR1A/SIX2/HOXA11	4
BP	GO:0014854	response to inactivity	4/2112	14/18670	0.06467	0.1883	0.1361	SGCA/HDAC4/DAG1/CAT	4
BP	GO:0030836	positive regulation of actin filament depolymerization	4/2112	14/18670	0.06467	0.1883	0.1361	PLEK/DSTN/CFL1/WDR1	4
BP	GO:0032688	negative regulation of interferon-beta production	4/2112	14/18670	0.06467	0.1883	0.1361	RELB/NMI/PTPRS/LILRB1	4
BP	GO:0036376	sodium ion export across plasma membrane	4/2112	14/18670	0.06467	0.1883	0.1361	FXYD1/ATP1B1/ATP1A2/SLC8A1	4
BP	GO:0043173	nucleotide salvage	4/2112	14/18670	0.06467	0.1883	0.1361	AMPD3/UPP1/ADK/ADA	4
BP	GO:0046033	AMP metabolic process	4/2112	14/18670	0.06467	0.1883	0.1361	AMPD3/NT5E/ADK/AK1	4
BP	GO:0046133	pyrimidine ribonucleoside catabolic process	4/2112	14/18670	0.06467	0.1883	0.1361	UPP1/APOBEC3G/APOBEC3B/ENTPD4	4
BP	GO:0048308	organelle inheritance	4/2112	14/18670	0.06467	0.1883	0.1361	VRK1/GOLGA2/CDK1/VCPIP1	4
BP	GO:0048313	Golgi inheritance	4/2112	14/18670	0.06467	0.1883	0.1361	VRK1/GOLGA2/CDK1/VCPIP1	4
BP	GO:0050930	induction of positive chemotaxis	4/2112	14/18670	0.06467	0.1883	0.1361	SCG2/CXCL8/IL16/VEGFB	4
BP	GO:0051712	positive regulation of killing of cells of other organism	4/2112	14/18670	0.06467	0.1883	0.1361	PRF1/CLEC7A/IFNG/SYK	4
BP	GO:0051938	L-glutamate import	4/2112	14/18670	0.06467	0.1883	0.1361	SLC1A3/PER2/ARL6IP5/ATP1A2	4
BP	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway	4/2112	14/18670	0.06467	0.1883	0.1361	JAK2/GHR/PRL/LYN	4
BP	GO:0070307	lens fiber cell development	4/2112	14/18670	0.06467	0.1883	0.1361	WNT5B/TMOD1/ABI2/CRYGB	4
BP	GO:0070672	response to interleukin-15	4/2112	14/18670	0.06467	0.1883	0.1361	IL2RG/IL15RA/IL2RB/IL15	4
BP	GO:0072498	embryonic skeletal joint development	4/2112	14/18670	0.06467	0.1883	0.1361	BMP4/SHOX2/HYAL1/HOXA11	4
BP	GO:0090231	regulation of spindle checkpoint	4/2112	14/18670	0.06467	0.1883	0.1361	NDC80/MAD2L1/TPR/CCNB1	4
BP	GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint	4/2112	14/18670	0.06467	0.1883	0.1361	NDC80/MAD2L1/TPR/CCNB1	4
BP	GO:0097202	activation of cysteine-type endopeptidase activity	4/2112	14/18670	0.06467	0.1883	0.1361	RIPK2/BAK1/ASPH/CYFIP2	4
BP	GO:1901213	regulation of transcription from RNA polymerase II promoter involved in heart development	4/2112	14/18670	0.06467	0.1883	0.1361	BMP4/BMPR1A/NOTCH1/ACVR1	4
BP	GO:1903504	regulation of mitotic spindle checkpoint	4/2112	14/18670	0.06467	0.1883	0.1361	NDC80/MAD2L1/TPR/CCNB1	4
BP	GO:1904152	regulation of retrograde protein transport, ER to cytosol	4/2112	14/18670	0.06467	0.1883	0.1361	EDEM1/UBE2J1/EDEM2/UBE2G2	4
BP	GO:2000345	regulation of hepatocyte proliferation	4/2112	14/18670	0.06467	0.1883	0.1361	TNFAIP3/PTN/CFLAR/LIMS2	4
BP	GO:2001044	regulation of integrin-mediated signaling pathway	4/2112	14/18670	0.06467	0.1883	0.1361	EMP2/ITGB1BP1/PRKD1/LIMS2	4
BP	GO:0016042	lipid catabolic process	47/2112	333/18670	0.06484	0.1886	0.1363	PLA2G2D/PLCE1/ALDH3A2/AKR1C3/ACADVL/ACOX2/STS/SGPL1/PNPLA6/SPHK1/ECHDC2/PLCG2/PLD1/ACAT1/SCARF1/PCK1/PLA2G12A/ETFB/ACACB/PLA2G4C/PCCA/LIPG/LEP/BDH2/PLIN1/ECI2/FUCA1/PLA1A/ADIPOQ/PRDX6/FABP5/ECI1/AOAH/GLA/FABP4/ABHD6/CYP46A1/ACADL/PDE3B/NAAA/HADH/ECHS1/LIPC/PLA2G7/IL1B/THRA/HADHA	47
BP	GO:0045137	development of primary sexual characteristics	33/2112	223/18670	0.06485	0.1886	0.1363	KITLG/PLEKHA1/SFRP1/ASPM/HOXA10/SOX9/FOXC1/SEMA3A/INHBA/AKR1C3/RHOBTB3/TNFSF10/AR/ZFPM2/SGPL1/ICAM1/SOD1/BCL2L2/FZD4/ATRX/IRX5/LEP/CCND1/FGF9/REC8/FOXO3/ANG/FSTL3/REN/ERCC1/HOXA11/NRIP1/PTX3	33
BP	GO:0001838	embryonic epithelial tube formation	20/2112	124/18670	0.06487	0.1886	0.1363	SFRP1/BMP4/LRP6/SOX9/SKI/SIX1/COBL/DLC1/SPINT2/TCTN1/VASP/TULP3/APAF1/FZD6/CFL1/DVL1/KIF20B/FZD2/PFN1/STIL	20
BP	GO:0045165	cell fate commitment	39/2112	270/18670	0.06536	0.19	0.1373	SLAMF8/GAS1/SFRP1/BMP4/BCL11B/WNT5B/HOXC10/SOX9/BATF/GLI3/CDON/NFE2L1/IRF4/SOX5/AR/EYA2/SIX1/BMPR1A/SIX2/GATA2/PDPN/FGF2/FGF13/TBX21/TCF7L2/SOX2/PITX1/FZD7/NOTCH1/HEY2/ACVR1/HOXD10/PAF1/IL6/TENM4/HOXA11/TP53/FEZF2/PML	39
BP	GO:0021549	cerebellum development	17/2112	102/18670	0.06548	0.1903	0.1375	CD3E/LRP6/MYH10/FOXC1/LPAR1/ZNF365/EZH2/PTN/PTPRS/FZD4/PTPN11/MECP2/PAK1/SDF4/CLP1/TP53/B4GALT2	17
BP	GO:0007416	synapse assembly	27/2112	177/18670	0.06558	0.1905	0.1376	SEMA4A/DLG5/PCDHB3/SPOCK2/SEMA4D/NTRK2/TLR2/PTPRD/SIX1/PCDHB13/PCDHB11/MAGI2/NLGN1/CLSTN1/EPHB1/PCDH17/PDLIM5/CDH2/RYK/PTPRS/EFNA5/MECP2/GPC4/MAP1B/LRRN3/DVL1/PCDHB6	27
BP	GO:0003171	atrioventricular valve development	6/2112	26/18670	0.06591	0.1908	0.1378	BMPR1A/DCHS1/NOTCH1/HEY2/ACVR1/HEY1	6
BP	GO:0021591	ventricular system development	6/2112	26/18670	0.06591	0.1908	0.1378	MYH10/TSKU/PAX5/MECP2/CENPF/MBOAT7	6
BP	GO:0032800	receptor biosynthetic process	6/2112	26/18670	0.06591	0.1908	0.1378	JAK2/IFNG/ADIPOQ/NR1H3/ITGAV/HOXA5	6
BP	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway	6/2112	26/18670	0.06591	0.1908	0.1378	IGFBP5/IGF1/IGFBP6/AR/CILP/IGFBP2	6
BP	GO:0072539	T-helper 17 cell differentiation	6/2112	26/18670	0.06591	0.1908	0.1378	BATF/IRF4/MALT1/TBX21/IL6/NLRP3	6
BP	GO:1900120	regulation of receptor binding	6/2112	26/18670	0.06591	0.1908	0.1378	PTPRF/LEF1/ADIPOQ/HFE/LDOC1/CRTAC1	6
BP	GO:1904353	regulation of telomere capping	6/2112	26/18670	0.06591	0.1908	0.1378	PRKCQ/NEK7/NEK2/AURKB/ERCC1/USP7	6
BP	GO:1903076	regulation of protein localization to plasma membrane	16/2112	95/18670	0.06699	0.1929	0.1394	PID1/PIK3R1/EPHA3/GBP1/PRKCH/CSK/AR/EGFR/RHOG/IFNG/STX4/SORBS1/CLIP3/VTI1B/RAB11FIP2/SPTBN1	16
BP	GO:0014741	negative regulation of muscle hypertrophy	8/2112	39/18670	0.06713	0.1929	0.1394	IGFBP5/TNFRSF1B/FOXO1/SMAD3/NOTCH1/PAK1/JARID2/LMNA	8
BP	GO:2000648	positive regulation of stem cell proliferation	8/2112	39/18670	0.06713	0.1929	0.1394	KITLG/PTPRC/ASPM/GLI3/LTBP3/SMARCD3/CX3CR1/NOTCH1	8
BP	GO:0042476	odontogenesis	21/2112	132/18670	0.06723	0.1929	0.1394	NFIC/BMP4/BCL11B/LRP6/TNFRSF11B/GLI3/FOXC1/INHBA/TCIRG1/HTRA1/PAM/BMPR1A/ID3/TP63/LEF1/FOXO1/CA2/TFAP2A/ALPL/TGFB3/SNX10	21
BP	GO:0055007	cardiac muscle cell differentiation	21/2112	132/18670	0.06723	0.1929	0.1394	SGCB/BMP4/IGF1/MYH10/CBY1/CDK1/SIK1/SORBS2/PDLIM5/NOX4/SGCD/FZD7/CCNB1/HEY2/SLC8A1/PAK1/ACVR1/AKAP13/MYH11/LMNA/ALPK3	21
BP	GO:0002320	lymphoid progenitor cell differentiation	5/2112	20/18670	0.06728	0.1929	0.1394	BMP4/BATF/NOTCH1/FLT3/SPI1	5
BP	GO:0003215	cardiac right ventricle morphogenesis	5/2112	20/18670	0.06728	0.1929	0.1394	ZFPM2/BMPR1A/SMARCD3/NOTCH1/HEY2	5
BP	GO:0030903	notochord development	5/2112	20/18670	0.06728	0.1929	0.1394	SOX9/COBL/YAP1/ID3/STIL	5
BP	GO:0032793	positive regulation of CREB transcription factor activity	5/2112	20/18670	0.06728	0.1929	0.1394	CD200/PRKD2/CAMK1D/RPS6KA4/PRKD1	5
BP	GO:0034143	regulation of toll-like receptor 4 signaling pathway	5/2112	20/18670	0.06728	0.1929	0.1394	TNFAIP3/MFHAS1/PTPN22/NR1H3/LYN	5
BP	GO:0042228	interleukin-8 biosynthetic process	5/2112	20/18670	0.06728	0.1929	0.1394	TLR8/CD74/CLEC7A/SYK/NOD1	5
BP	GO:0043691	reverse cholesterol transport	5/2112	20/18670	0.06728	0.1929	0.1394	CLU/ABCG1/LIPG/CETP/LIPC	5
BP	GO:0043931	ossification involved in bone maturation	5/2112	20/18670	0.06728	0.1929	0.1394	IGF1/SEMA4D/DCHS1/LEP/FAT4	5
BP	GO:0046823	negative regulation of nucleocytoplasmic transport	5/2112	20/18670	0.06728	0.1929	0.1394	ANGPT1/CD36/TPR/BARD1/FERMT1	5
BP	GO:0048745	smooth muscle tissue development	5/2112	20/18670	0.06728	0.1929	0.1394	BMP4/SOX9/SIX1/PKD2/MYLK	5
BP	GO:0070828	heterochromatin organization	5/2112	20/18670	0.06728	0.1929	0.1394	TPR/HELLS/HMGA1/SMCHD1/HP1BP3	5
BP	GO:0071636	positive regulation of transforming growth factor beta production	5/2112	20/18670	0.06728	0.1929	0.1394	XCL1/CD200/LGALS9/LUM/SMAD3	5
BP	GO:1901673	regulation of mitotic spindle assembly	5/2112	20/18670	0.06728	0.1929	0.1394	PLK1/TPR/STAG2/CHMP2B/CHMP1B	5
BP	GO:1902993	positive regulation of amyloid precursor protein catabolic process	5/2112	20/18670	0.06728	0.1929	0.1394	CLU/ABCG1/SPON1/IFNG/LYN	5
BP	GO:1903978	regulation of microglial cell activation	5/2112	20/18670	0.06728	0.1929	0.1394	PTPRC/CST7/CTSC/SPHK1/IL6	5
BP	GO:1900407	regulation of cellular response to oxidative stress	15/2112	88/18670	0.06838	0.1959	0.1416	GCH1/OXR1/CD36/FBLN5/LANCL1/HGF/SOD1/RGN/PARP1/HSPB1/PINK1/FOXO3/BAG5/FUT8/TLR6	15
BP	GO:1901888	regulation of cell junction assembly	15/2112	88/18670	0.06838	0.1959	0.1416	SFRP1/EPHA3/LIMCH1/PRKCH/ITGB1BP1/DLC1/EFNA5/SMAD3/MYOC/PPM1F/MYO1C/RHOD/KDR/COL16A1/NPHP4	15
BP	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	20/2112	125/18670	0.06937	0.1987	0.1435	CDKN2C/TFDP2/KANK2/BTN2A2/E2F8/FHL1/CDK1/EZH2/PLK2/CCNB1/DACT1/CCND1/RB1/PKD2/PRMT1/PCBP4/TP53/CCL2/AURKA/PML	20
BP	GO:0016126	sterol biosynthetic process	14/2112	81/18670	0.06959	0.1991	0.1438	LBR/ABCG1/PMVK/CYB5R3/FAXDC2/ERLIN1/SP1/SOD1/ACACB/CYB5R1/SC5D/NFYA/ERLIN2/MBTPS2	14
BP	GO:0030811	regulation of nucleotide catabolic process	14/2112	81/18670	0.06959	0.1991	0.1438	IGF1/ZBTB20/SLC2A6/CBFA2T3/NUP93/HDAC4/TPR/NUP160/HTR2A/IFNG/ARNT/NUP88/NUP50/TP53	14
BP	GO:0030810	positive regulation of nucleotide biosynthetic process	9/2112	46/18670	0.06967	0.1991	0.1438	PID1/IGF1/ZBTB20/HTR2A/VCP/IFNG/ARNT/PINK1/GUCA1A	9
BP	GO:0043277	apoptotic cell clearance	9/2112	46/18670	0.06967	0.1991	0.1438	FCN1/AXL/CD36/NR1H3/MERTK/TGM2/ITGAV/CCL2/RAB14	9
BP	GO:1900373	positive regulation of purine nucleotide biosynthetic process	9/2112	46/18670	0.06967	0.1991	0.1438	PID1/IGF1/ZBTB20/HTR2A/VCP/IFNG/ARNT/PINK1/GUCA1A	9
BP	GO:0009123	nucleoside monophosphate metabolic process	52/2112	375/18670	0.07037	0.201	0.1452	ENPP1/PID1/AMPD3/IGF1/NT5E/ZBTB20/NDUFC1/UPP1/BID/ADK/NDUFS2/SLC2A6/CBFA2T3/COX7A1/NUP93/HDAC4/NDUFS4/HK3/ADA/ALDOC/TPR/CDK1/NDUFA13/NUP160/AK1/HTR2A/ATP1B1/VCP/IFNG/ARNT/CCNB1/ATP1A2/MECP2/NUDT11/PARP1/SLC25A23/PINK1/NDUFA9/TYMS/NUP88/SDHA/NDUFB6/TK2/NUP50/TK1/TP53/ATP6V1B2/CASK/NDUFA4/AK6/PRPS2/COX7A2	52
BP	GO:0048259	regulation of receptor-mediated endocytosis	17/2112	103/18670	0.07053	0.2011	0.1453	CLU/CCL19/ANGPT1/TBC1D5/USP46/WASL/SELE/PLCG2/CCL21/MAGI2/LRPAP1/SYK/HFE/ATXN2/MTMR2/SH3GL3/AHI1	17
BP	GO:0031670	cellular response to nutrient	13/2112	74/18670	0.07057	0.2011	0.1453	SFRP1/PENK/IL15/PIM1/KANK2/TRIM24/PTN/SOD1/LEP/BCL11A/RYR3/CYBA/P2RY4	13
BP	GO:0070373	negative regulation of ERK1 and ERK2 cascade	13/2112	74/18670	0.07057	0.2011	0.1453	PTPRC/GBP1/CSK/TIMP3/LMO3/PTPN2/ITGB1BP1/BTN2A2/ADIPOQ/DUSP6/FBLN1/LYN/NDRG2	13
BP	GO:0072395	signal transduction involved in cell cycle checkpoint	13/2112	74/18670	0.07057	0.2011	0.1453	TFDP2/DTL/PLK1/CDC14B/E2F8/CDK1/PLK2/CCNB1/PRMT1/PCBP4/TP53/AURKA/PML	13
BP	GO:1900182	positive regulation of protein localization to nucleus	13/2112	74/18670	0.07057	0.2011	0.1453	PIK3R1/ZIC1/GLI3/HCLS1/PLK1/TPR/CDK1/ZPR1/SMAD3/ECT2/LEP/IFNG/PARP1	13
BP	GO:0036294	cellular response to decreased oxygen levels	32/2112	217/18670	0.07077	0.2016	0.1456	PSMB9/NDNF/SFRP1/PSMB8/PSMB10/ICAM1/ADAM8/PSME1/CPEB1/CREBBP/KCNK2/CCNA2/PCK1/PTN/PMAIP1/BACH1/FAM162A/NOTCH1/HIGD1A/ZFP36L1/ARNT/CCNB1/SLC8A1/PINK1/CUL2/FOXO3/LMNA/HIPK2/CFLAR/TP53/BNIP3L/HP1BP3	32
BP	GO:0032715	negative regulation of interleukin-6 production	10/2112	53/18670	0.07098	0.2019	0.1459	TNFAIP3/IL27RA/SLAMF1/CSK/CD200/PTPN6/HGF/NCKAP1L/PTPN22/INPP5D	10
BP	GO:0043331	response to dsRNA	10/2112	53/18670	0.07098	0.2019	0.1459	RFTN1/IFIH1/RIPK2/NFKBIA/DDX58/NFKB1/PMAIP1/COLEC12/DDX1/IFNA1	10
BP	GO:1905517	macrophage migration	10/2112	53/18670	0.07098	0.2019	0.1459	CCL5/SLAMF8/CCR2/CD200/CX3CR1/CD9/EDNRB/MTUS1/CD81/CCL2	10
BP	GO:2000573	positive regulation of DNA biosynthetic process	12/2112	67/18670	0.07122	0.2024	0.1463	PRKCQ/PRKD2/FGF2/HGF/NOX4/NEK7/RFC3/NEK2/HSP90AB1/AURKB/PARM1/PARN	12
BP	GO:0048562	embryonic organ morphogenesis	41/2112	288/18670	0.07207	0.2048	0.1479	BMP4/LRP6/ZIC1/SOX9/GLI3/SIX1/SIX2/SHOX2/YAP1/GATA2/SOBP/TCF7/HOXC4/CHST11/SOD1/EFEMP1/HYAL1/SMAD3/RBP4/IRX5/NOTCH1/PAX5/TFAP2A/HOXA4/ACVR1/FGF9/HOXD10/TGFB3/NIPBL/TULP3/FZD6/MEGF8/HIPK2/PKD2/DVL1/MYO3A/HOXA11/FZD2/HOXA5/STIL/AHI1	41
BP	GO:0010837	regulation of keratinocyte proliferation	7/2112	33/18670	0.07226	0.2048	0.1479	BCL11B/FGF7/YAP1/TP63/ZFP36L1/PRKD1/CASK	7
BP	GO:0018279	protein N-linked glycosylation via asparagine	7/2112	33/18670	0.07226	0.2048	0.1479	DPM3/MAGT1/VCP/UBE2J1/STT3A/FUT8/UBE2G2	7
BP	GO:0030513	positive regulation of BMP signaling pathway	7/2112	33/18670	0.07226	0.2048	0.1479	GDF5/BMP4/SULF1/TWSG1/NEO1/NOTCH1/CDH5	7
BP	GO:0035115	embryonic forelimb morphogenesis	7/2112	33/18670	0.07226	0.2048	0.1479	SHOX2/ZNF358/RECK/TP63/TFAP2A/NIPBL/HOXA11	7
BP	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	7/2112	33/18670	0.07226	0.2048	0.1479	CDKN2C/TNFAIP3/CDKN1C/PLK1/HEXIM1/IPO7/CEBPA	7
BP	GO:1902692	regulation of neuroblast proliferation	7/2112	33/18670	0.07226	0.2048	0.1479	ASPM/GLI3/SMARCD3/CX3CR1/PTN/NOTCH1/TP53	7
BP	GO:0051321	meiotic cell cycle	36/2112	249/18670	0.07334	0.2077	0.1501	ASPM/PTTG1/PPP2CA/PTTG3P/BUB1/NCAPD2/NPR2/GOLGA2/PLK1/UBE2B/NCAPH/CDC25B/STAG2/BUB1B/DAZL/TOP2A/NEK2/MYBL1/RMI1/ATRX/CKS2/STAG3/TERF1/FBXO5/REC8/TTK/CDC20/TUBG2/ERCC1/SMC4/ACTR3/TRIP13/CCNE2/AURKA/ACTR2/SPIN1	36
BP	GO:0006323	DNA packaging	31/2112	210/18670	0.07353	0.2081	0.1503	NAP1L2/NAP1L3/SOX9/NUSAP1/NCAPD2/NCAPH/SRPK1/SMARCA1/HJURP/NCAPG/TPR/CDK1/TSPYL2/MCPH1/TOP2A/ATRX/MCM2/CCNB1/ASF1B/KAT6B/NIPBL/PAF1/HELLS/RSF1/CHAF1B/HMGA1/SMC4/CENPM/SMCHD1/TP53/HP1BP3	31
BP	GO:0030178	negative regulation of Wnt signaling pathway	31/2112	210/18670	0.07353	0.2081	0.1503	PSMB9/SFRP1/PSMB8/LRP6/WNT5B/RBMS3/PSMB10/SOX9/GLI3/TSKU/CBY1/IGFBP6/PSME1/TCF7L2/SOX2/CDH2/FOXO1/NOTCH1/DACT1/FGF9/WWTR1/FZD6/DDIT3/NLK/FOXO3/FERMT1/IGFBP2/DVL1/DKK3/WIF1/NPHP4	31
BP	GO:0009411	response to UV	22/2112	141/18670	0.07379	0.2087	0.1508	PIK3R1/SCARA3/DTL/MFAP4/EGFR/UBE2B/CREBBP/BAK1/PTN/MAPK13/FEN1/HYAL1/CCND1/PARP1/AURKB/SDF4/CUL4B/CAT/ERCC1/PBK/TP53/PML	22
BP	GO:0060021	roof of mouth development	15/2112	89/18670	0.07403	0.2092	0.1511	PLEKHA1/LRP6/GLI3/SKI/INHBA/SGPL1/BMPR1A/DHRS3/TGFBR3/ASPH/LEF1/TFAP2A/TGFB3/LRRC32/FZD2	15
BP	GO:1901019	regulation of calcium ion transmembrane transporter activity	15/2112	89/18670	0.07403	0.2092	0.1511	SRI/CACNA2D1/ANK2/DYSF/GEM/PLCG2/PLN/ATP1B1/RGN/ATP1A2/FGF14/P2RY6/PKD2/GSTO1/GSTM2	15
BP	GO:1901343	negative regulation of vasculature development	28/2112	187/18670	0.07439	0.2101	0.1518	CCR2/BMP4/SEMA4A/STAT1/FOXC1/ITGB1BP1/SULF1/HLA-G/CXCL10/THBS4/DCN/CD160/CX3CR1/PTN/DNMT1/TNMD/PLK2/NOTCH1/MECP2/PRL/HEY2/FGF9/SEMA3E/PDE3B/SPINK5/GPR4/HOXA5/PML	28
BP	GO:0010976	positive regulation of neuron projection development	40/2112	281/18670	0.07491	0.2115	0.1528	NDNF/EPHA3/S100A9/DLG5/CXCR4/SEMA4D/NTRK2/LPAR1/PTPRD/ITSN1/COBL/SHOX2/TUBB2B/TRPV2/CREB3L2/HGF/MAGI2/NLGN1/EZH2/SCARF1/CAMK1D/PTN/FZD4/EFNA5/SCN1B/FEZ1/GDI1/SERPINI1/SYT17/PAK1/DPYSL3/SCARB2/CHODL/MAP1B/MEGF8/PRKD1/LYN/DVL1/CFLAR/ACTR2	40
BP	GO:0071453	cellular response to oxygen levels	34/2112	234/18670	0.07568	0.2136	0.1543	PSMB9/NDNF/SFRP1/PSMB8/PSMB10/LPAR1/ICAM1/ADAM8/PSME1/CPEB1/CREBBP/KCNK2/CCNA2/PCK1/PTN/PMAIP1/BACH1/FOXO1/FAM162A/NOTCH1/HIGD1A/ZFP36L1/ARNT/CCNB1/SLC8A1/PINK1/CUL2/FOXO3/LMNA/HIPK2/CFLAR/TP53/BNIP3L/HP1BP3	34
BP	GO:0007173	epidermal growth factor receptor signaling pathway	19/2112	119/18670	0.07649	0.2158	0.1559	PIK3R1/BTC/PLCE1/RHBDF2/SOX9/PTPN2/EGFR/GPRC5A/HBEGF/ZGPAT/RHBDF1/EFEMP1/SNX5/PTPN11/KIF16B/PIK3CA/FER/NCF1/CAMLG	19
BP	GO:0001707	mesoderm formation	13/2112	75/18670	0.07693	0.2162	0.1562	BMP4/FOXC1/INHBA/EYA2/BMPR1A/WLS/SIX2/TWSG1/LEF1/SMAD3/ACVR1/EXT2/HOXA11	13
BP	GO:0002200	somatic diversification of immune receptors	13/2112	75/18670	0.07693	0.2162	0.1562	PTPRC/BCL11B/IL27RA/BATF/CD40/TFRC/TCF7/TBX21/CD40LG/LEF1/ADAR/ERCC1/THOC1	13
BP	GO:0039528	cytoplasmic pattern recognition receptor signaling pathway in response to virus	6/2112	27/18670	0.07698	0.2162	0.1562	BIRC3/IRF7/IFIH1/TSPAN6/DDX58/DDX60	6
BP	GO:0043921	modulation by host of viral transcription	6/2112	27/18670	0.07698	0.2162	0.1562	CCL5/NUCKS1/CHD1/CCNT1/SP1/LEF1	6
BP	GO:0048668	collateral sprouting	6/2112	27/18670	0.07698	0.2162	0.1562	SEMA4D/COBL/FGF13/PTPRS/EFNA5/DVL1	6
BP	GO:0048799	animal organ maturation	6/2112	27/18670	0.07698	0.2162	0.1562	IGF1/SEMA4D/DCHS1/LEP/FAT4/MBTPS2	6
BP	GO:0052472	modulation by host of symbiont transcription	6/2112	27/18670	0.07698	0.2162	0.1562	CCL5/NUCKS1/CHD1/CCNT1/SP1/LEF1	6
BP	GO:0071450	cellular response to oxygen radical	6/2112	27/18670	0.07698	0.2162	0.1562	GCH1/NQO1/CD36/FBLN5/SOD1/RGN	6
BP	GO:0071451	cellular response to superoxide	6/2112	27/18670	0.07698	0.2162	0.1562	GCH1/NQO1/CD36/FBLN5/SOD1/RGN	6
BP	GO:0031667	response to nutrient levels	67/2112	499/18670	0.07734	0.2172	0.1569	CD3E/SFRP1/TNFRSF11B/PENK/GABARAPL1/NQO1/STAT1/IL15/PIM1/KYNU/AKR1C3/OXCT1/UPP1/TBC1D5/KANK2/ICAM1/NOD2/CXCL10/TRIM24/EGFR/GABARAPL2/ADA/DAP/SIK1/ACAT1/PCK1/PTN/SOD1/ACACB/PMAIP1/FOXO1/RMI1/LIPG/LEP/HIGD1A/PSPH/DSC2/PRL/TMEM135/SLC8A1/ALPL/ADIPOQ/CCND1/PDK4/HFE/APAF1/MAP1B/TYMS/BCL11A/DDIT3/BCKDHB/RYR3/FOXO3/ENSA/CYBA/PRKD1/SESN1/IGFBP2/PANX1/CAT/ERCC1/ALAD/TP53/GSN/IL1B/P2RY4/TXN2	67
BP	GO:0002204	somatic recombination of immunoglobulin genes involved in immune response	9/2112	47/18670	0.07792	0.2178	0.1573	PTPRC/IL27RA/BATF/CD40/TFRC/TBX21/CD40LG/ERCC1/THOC1	9
BP	GO:0002208	somatic diversification of immunoglobulins involved in immune response	9/2112	47/18670	0.07792	0.2178	0.1573	PTPRC/IL27RA/BATF/CD40/TFRC/TBX21/CD40LG/ERCC1/THOC1	9
BP	GO:0006953	acute-phase response	9/2112	47/18670	0.07792	0.2178	0.1573	SERPINA1/SERPINA3/CD163/EDNRB/HFE/IL6/PLSCR1/HP/IL1B	9
BP	GO:0018198	peptidyl-cysteine modification	9/2112	47/18670	0.07792	0.2178	0.1573	S100A9/OXR1/ZDHHC18/ADH5/HMBS/CLIP3/GOLGA7/SNTA1/ZDHHC14	9
BP	GO:0045190	isotype switching	9/2112	47/18670	0.07792	0.2178	0.1573	PTPRC/IL27RA/BATF/CD40/TFRC/TBX21/CD40LG/ERCC1/THOC1	9
BP	GO:0060986	endocrine hormone secretion	9/2112	47/18670	0.07792	0.2178	0.1573	INHBA/TAC1/FZD4/PTPN11/LEP/AGTR1/REN/IL1B/RAB11FIP1	9
BP	GO:1900744	regulation of p38MAPK cascade	9/2112	47/18670	0.07792	0.2178	0.1573	SPHK1/HGF/MFHAS1/LEP/PHLPP1/PTPN22/NCF1/PRMT1/IL1B	9
BP	GO:1901659	glycosyl compound biosynthetic process	9/2112	47/18670	0.07792	0.2178	0.1573	TYMP/NT5E/UPP1/ADK/NME7/ADA/NME4/TK2/TK1	9
BP	GO:0001657	ureteric bud development	16/2112	97/18670	0.07794	0.2178	0.1573	SFRP1/CRLF1/BMP4/SOX9/GLI3/FOXC1/SIX1/SIX2/FGF2/PBX1/DCHS1/SMAD3/FAT4/PKD2/CAT/HOXA11	16
BP	GO:0043255	regulation of carbohydrate biosynthetic process	16/2112	97/18670	0.07794	0.2178	0.1573	ENPP1/IGF1/PTPN2/PASK/PLEK/SIK1/FAM3C/NFKB1/FOXO1/HRH1/LEP/PPP1CA/ADIPOQ/P2RY6/SORBS1/PTH1R	16
BP	GO:0060996	dendritic spine development	16/2112	97/18670	0.07794	0.2178	0.1573	DLG5/DOCK10/LPAR1/ZNF365/ITSN1/WASL/NLGN1/EPHB1/PDLIM5/PTPRS/PLK2/CFL1/ADAM10/DVL1/ABI2/ACTR2	16
BP	GO:0043583	ear development	32/2112	219/18670	0.078	0.2178	0.1574	BMP4/ZIC1/SOX9/GLI3/SIX1/SIX2/GATA2/SOBP/KCNK2/CCNA2/SOX2/SOD1/DCHS1/PTPN11/NOTCH1/MCM2/HEY2/TFAP2A/LRP10/FGF9/TGFB3/NIPBL/MAPKAPK2/FZD6/FAT4/ADAM10/CEBPA/DVL1/MYO3A/FZD2/MYCL/AHI1	32
BP	GO:0034330	cell junction organization	41/2112	290/18670	0.07837	0.2187	0.158	SFRP1/EPHA3/LIMCH1/PRKCH/CSK/DLG5/CDH19/PARD3/ANK2/MAPRE2/ITGB1BP1/FERMT2/TNS1/DLC1/CDH2/CADM1/EFNA5/SMAD3/VASP/CORO2B/CD9/MYOC/ECT2/PECAM1/PPM1F/MYO1C/TRIP6/SORBS1/TGFB3/CTTN/RHOD/CAPZA1/ANG/MPP5/KDR/GJC1/WDR1/LIMS2/COL16A1/NPHP4/CDH5	41
BP	GO:1901292	nucleoside phosphate catabolic process	28/2112	188/18670	0.07839	0.2187	0.158	ENPP1/AMPD3/IGF1/NT5E/ZBTB20/UPP1/SLC2A6/CBFA2T3/NUP93/HDAC4/HK3/ADA/ALDOC/PDE1A/TPR/ACAT1/NUP160/HTR2A/VCP/IFNG/ARNT/NUDT11/PNP/ENTPD4/NUP88/HINT1/NUP50/TP53	28
BP	GO:0003170	heart valve development	11/2112	61/18670	0.07863	0.2188	0.1581	BMP4/TNFRSF1B/SOX9/BMPR1A/SHOX2/DCHS1/NOTCH1/HEY2/ACVR1/RB1/HEY1	11
BP	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	11/2112	61/18670	0.07863	0.2188	0.1581	TNFAIP3/BIRC3/TRAF1/PTPN2/SPHK1/CASP1/ADIPOQ/SYK/IKBKG/CLIP3/CASP4	11
BP	GO:0042733	embryonic digit morphogenesis	11/2112	61/18670	0.07863	0.2188	0.1581	BMP4/TMEM231/ZBTB16/GLI3/BMPR1A/CREBBP/CHST11/NOTCH1/TULP3/FZD6/HOXA11	11
BP	GO:0045604	regulation of epidermal cell differentiation	11/2112	61/18670	0.07863	0.2188	0.1581	BMP4/PRKCH/FOXC1/CTSL/KLF7/EZH2/TP63/NOTCH1/ZFP36L1/HEY2/MYCL	11
BP	GO:0050803	regulation of synapse structure or activity	33/2112	227/18670	0.07868	0.2188	0.1581	SEMA4A/DLG5/LILRB2/SEMA4D/NTRK2/TLR2/PTPRD/SIX1/ITSN1/DNM1/DAG1/ETV5/ARHGAP22/NLGN1/CLSTN1/EPHB1/PTN/PDLIM5/CDH2/PTPRS/SEMA3F/EFNA5/VCP/IL10RA/GPC4/SYBU/CHMP2B/CFL1/LRRN3/ADAM10/CDC20/ABI2/ACTR2	33
BP	GO:0035384	thioester biosynthetic process	10/2112	54/18670	0.07869	0.2188	0.1581	MPC2/ACAT1/ACACB/HSD17B12/PDK4/ELOVL4/MPC1/ELOVL2/ACSL5/ELOVL5	10
BP	GO:0051353	positive regulation of oxidoreductase activity	10/2112	54/18670	0.07869	0.2188	0.1581	GCH1/NOD2/HTR2B/AGTR1/IFNG/RGN/CYBA/NOD1/NPR3/IL1B	10
BP	GO:0071616	acyl-CoA biosynthetic process	10/2112	54/18670	0.07869	0.2188	0.1581	MPC2/ACAT1/ACACB/HSD17B12/PDK4/ELOVL4/MPC1/ELOVL2/ACSL5/ELOVL5	10
BP	GO:0015918	sterol transport	18/2112	112/18670	0.07894	0.2193	0.1584	LRP6/CLU/ABCG1/CD36/AKR1C1/NPC1/NFKBIA/NFKB1/LIPG/LEP/STARD5/ADIPOQ/CETP/NR1H3/OSBPL1A/OSBPL9/LIPC/SOAT2	18
BP	GO:0006694	steroid biosynthetic process	29/2112	196/18670	0.0794	0.2193	0.1584	LBR/AKR1C3/ABCG1/ACOX2/PMVK/AKR1B1/CYB5R3/FAXDC2/ERLIN1/SP1/SOD1/ACACB/PBX1/CYB5R1/NFKB1/SC5D/HSD17B12/LEP/IFNG/NFYA/ERLIN2/GFI1/OSBPL1A/MBTPS2/SLC27A5/CYP46A1/OSBPL9/DKK3/IL1B	29
BP	GO:0009100	glycoprotein metabolic process	57/2112	419/18670	0.08038	0.2193	0.1584	NDNF/IGF1/GALNT11/SPOCK2/CCL19/IL15/CHST15/CCR7/SULF1/MGAT4C/EXTL2/B3GALNT1/GALNT10/GOLGA2/TRAK2/HBEGF/CHST3/ALG6/DCN/NPC1/BGN/DPM3/MAGT1/CCL21/CSPG4/TCF7L2/GAL3ST4/CHST11/VCAN/HYAL1/EDEM1/FAM20B/UGDH/IDUA/VCP/GFPT1/LEP/DPY19L4/EXT2/B3GNT2/MAN1C1/SDF2L1/UBE2J1/VEGFB/MAN2B1/STT3A/EDEM2/MAN2A2/FUT8/CANT1/MANBA/GFPT2/FUT4/MMP12/PTX3/UBE2G2/B4GALT2	57
BP	GO:0002438	acute inflammatory response to antigenic stimulus	5/2112	21/18670	0.08042	0.2193	0.1584	CCR7/ICAM1/HLA-E/CD6/BTK	5
BP	GO:0003177	pulmonary valve development	5/2112	21/18670	0.08042	0.2193	0.1584	BMP4/TNFRSF1B/NOTCH1/HEY2/HEY1	5
BP	GO:0030502	negative regulation of bone mineralization	5/2112	21/18670	0.08042	0.2193	0.1584	ENPP1/SOX9/LTBP3/SRGN/CCR1	5
BP	GO:0030728	ovulation	5/2112	21/18670	0.08042	0.2193	0.1584	INHBA/IL4R/LEP/FOXO3/NRIP1	5
BP	GO:0042135	neurotransmitter catabolic process	5/2112	21/18670	0.08042	0.2193	0.1584	ALDH7A1/MAOA/NAALAD2/MAOB/ALDH5A1	5
BP	GO:0046827	positive regulation of protein export from nucleus	5/2112	21/18670	0.08042	0.2193	0.1584	TPR/TCF7L2/TP53/IL1B/XPO4	5
BP	GO:0071459	protein localization to chromosome, centromeric region	5/2112	21/18670	0.08042	0.2193	0.1584	NDC80/CDK1/TTK/AURKB/RB1	5
BP	GO:0072010	glomerular epithelium development	5/2112	21/18670	0.08042	0.2193	0.1584	BMP4/FOXC1/MAGI2/PECAM1/ADIPOQ	5
BP	GO:1901739	regulation of myoblast fusion	5/2112	21/18670	0.08042	0.2193	0.1584	CXCL9/IL4R/CXCL10/CD53/CFLAR	5
BP	GO:1902473	regulation of protein localization to synapse	5/2112	21/18670	0.08042	0.2193	0.1584	DAG1/NLGN1/GPC4/ADAM10/DVL1	5
BP	GO:1902884	positive regulation of response to oxidative stress	5/2112	21/18670	0.08042	0.2193	0.1584	ACOX2/SOD1/RGN/FOXO3/TLR6	5
BP	GO:1904469	positive regulation of tumor necrosis factor secretion	5/2112	21/18670	0.08042	0.2193	0.1584	LGALS9/IFIH1/AKAP12/DDX58/IFNG	5
BP	GO:1904886	beta-catenin destruction complex disassembly	5/2112	21/18670	0.08042	0.2193	0.1584	LRP6/PPP1CA/DVL1/FZD2/FRAT1	5
BP	GO:2000316	regulation of T-helper 17 type immune response	5/2112	21/18670	0.08042	0.2193	0.1584	IL27RA/PRKCQ/MALT1/TBX21/NLRP3	5
BP	GO:2000678	negative regulation of transcription regulatory region DNA binding	5/2112	21/18670	0.08042	0.2193	0.1584	SRI/PER2/HEY2/DDIT3/HEY1	5
BP	GO:0002467	germinal center formation	4/2112	15/18670	0.08057	0.2193	0.1584	CXCL13/TNFAIP3/NFKB2/ADA	4
BP	GO:0009415	response to water	4/2112	15/18670	0.08057	0.2193	0.1584	SIPA1/AKR1B1/CD9/PKD2	4
BP	GO:0017014	protein nitrosylation	4/2112	15/18670	0.08057	0.2193	0.1584	S100A9/OXR1/ADH5/SNTA1	4
BP	GO:0018119	peptidyl-cysteine S-nitrosylation	4/2112	15/18670	0.08057	0.2193	0.1584	S100A9/OXR1/ADH5/SNTA1	4
BP	GO:0019321	pentose metabolic process	4/2112	15/18670	0.08057	0.2193	0.1584	RPIA/PGD/FGGY/TALDO1	4
BP	GO:0030299	intestinal cholesterol absorption	4/2112	15/18670	0.08057	0.2193	0.1584	CD36/AKR1C1/LEP/SOAT2	4
BP	GO:0032736	positive regulation of interleukin-13 production	4/2112	15/18670	0.08057	0.2193	0.1584	IRF4/LGALS9/HLA-E/NLRP3	4
BP	GO:0033689	negative regulation of osteoblast proliferation	4/2112	15/18670	0.08057	0.2193	0.1584	NELL1/SFRP1/SMAD3/ATRAID	4
BP	GO:0036445	neuronal stem cell division	4/2112	15/18670	0.08057	0.2193	0.1584	ASPM/SOX5/FGF13/LEF1	4
BP	GO:0042362	fat-soluble vitamin biosynthetic process	4/2112	15/18670	0.08057	0.2193	0.1584	NFKB1/IFNG/GFI1/IL1B	4
BP	GO:0042976	activation of Janus kinase activity	4/2112	15/18670	0.08057	0.2193	0.1584	CCL5/JAK2/SOCS1/GHR	4
BP	GO:0043101	purine-containing compound salvage	4/2112	15/18670	0.08057	0.2193	0.1584	AMPD3/ADK/ADA/PNP	4
BP	GO:0043584	nose development	4/2112	15/18670	0.08057	0.2193	0.1584	GLI3/SKI/SIX1/SMCHD1	4
BP	GO:0045073	regulation of chemokine biosynthetic process	4/2112	15/18670	0.08057	0.2193	0.1584	CD74/IFNG/IL6/IL1B	4
BP	GO:0045837	negative regulation of membrane potential	4/2112	15/18670	0.08057	0.2193	0.1584	PTN/ARL6IP5/PMAIP1/BNIP3L	4
BP	GO:0048569	post-embryonic animal organ development	4/2112	15/18670	0.08057	0.2193	0.1584	BCL11B/BAK1/EFEMP1/ERCC1	4
BP	GO:0050651	dermatan sulfate proteoglycan biosynthetic process	4/2112	15/18670	0.08057	0.2193	0.1584	DCN/BGN/CSPG4/VCAN	4
BP	GO:0050961	detection of temperature stimulus involved in sensory perception	4/2112	15/18670	0.08057	0.2193	0.1584	CXCR4/EPHB1/HTR2A/LXN	4
BP	GO:0050965	detection of temperature stimulus involved in sensory perception of pain	4/2112	15/18670	0.08057	0.2193	0.1584	CXCR4/EPHB1/HTR2A/LXN	4
BP	GO:0051044	positive regulation of membrane protein ectodomain proteolysis	4/2112	15/18670	0.08057	0.2193	0.1584	TNFRSF1B/ADAM8/IFNG/IL1B	4
BP	GO:0051127	positive regulation of actin nucleation	4/2112	15/18670	0.08057	0.2193	0.1584	WASL/WAS/ABI2/GSN	4
BP	GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	4/2112	15/18670	0.08057	0.2193	0.1584	SRI/PKD2/GSTO1/GSTM2	4
BP	GO:0055057	neuroblast division	4/2112	15/18670	0.08057	0.2193	0.1584	ASPM/SOX5/FGF13/LEF1	4
BP	GO:0072160	nephron tubule epithelial cell differentiation	4/2112	15/18670	0.08057	0.2193	0.1584	STAT1/YAP1/WWTR1/FAT4	4
BP	GO:0090192	regulation of glomerulus development	4/2112	15/18670	0.08057	0.2193	0.1584	BMP4/PDGFD/ADIPOQ/CFLAR	4
BP	GO:1900119	positive regulation of execution phase of apoptosis	4/2112	15/18670	0.08057	0.2193	0.1584	DLC1/IL6/TP53BP2/TP53	4
BP	GO:1903358	regulation of Golgi organization	4/2112	15/18670	0.08057	0.2193	0.1584	PDE4DIP/RAB33B/STX18/CAMSAP2	4
BP	GO:1905874	regulation of postsynaptic density organization	4/2112	15/18670	0.08057	0.2193	0.1584	LILRB2/PTPRD/CDH2/PTPRS	4
BP	GO:2000402	negative regulation of lymphocyte migration	4/2112	15/18670	0.08057	0.2193	0.1584	IL27RA/CD200/WASL/CCL2	4
BP	GO:2000484	positive regulation of interleukin-8 secretion	4/2112	15/18670	0.08057	0.2193	0.1584	CD2/FCN1/TLR2/LGALS9	4
BP	GO:1903322	positive regulation of protein modification by small protein conjugation or removal	21/2112	135/18670	0.08123	0.221	0.1597	BIRC3/ANGPT1/UBE2C/NOD2/MALT1/GOLGA2/PLK1/NMI/HDAC4/RIPK2/CDC14B/FANCI/CHFR/SPHK1/UBE2D1/VCP/ARNT/PINK1/PTPN22/CDC20/NDFIP1	21
BP	GO:0045185	maintenance of protein location	17/2112	105/18670	0.08139	0.2213	0.1599	SRI/SKP1/NFKBIE/TMSB10/SRGN/DAG1/DZIP1/BARD1/GPAA1/NFKBIA/KDELR3/NBL1/KDELR2/PINK1/PKD2/GSN/PML	17
BP	GO:0002526	acute inflammatory response	32/2112	220/18670	0.0818	0.2223	0.1606	SERPINA1/CLU/SERPINA3/CCR7/ICAM1/ADAM8/CFP/HLA-E/PROS1/TAC1/CR1/CD6/CD19/IL6ST/IGLC1/IGLV1-44/C7/CD163/ACVR1/EDNRB/HFE/BTK/IL6/IGHG1/PLSCR1/HP/CFB/CD81/IL1B/CR2/C6/NLRP3	32
BP	GO:0045913	positive regulation of carbohydrate metabolic process	14/2112	83/18670	0.0819	0.2224	0.1607	IGF1/ZBTB20/PTPN2/NFKB1/PMAIP1/HTR2A/FOXO1/HRH1/IFNG/ARNT/RGN/P2RY6/SORBS1/PTH1R	14
BP	GO:0048145	regulation of fibroblast proliferation	14/2112	83/18670	0.0819	0.2224	0.1607	SFRP1/IGF1/DDR2/BTC/SKI/CD74/PDGFD/NDUFS4/EGFR/SPHK1/CCNA2/CCNB1/TP53/PML	14
BP	GO:0010574	regulation of vascular endothelial growth factor production	7/2112	34/18670	0.08252	0.2237	0.1616	CCR2/SULF1/IL6ST/ARNT/IL6/NDRG2/IL1B	7
BP	GO:0018196	peptidyl-asparagine modification	7/2112	34/18670	0.08252	0.2237	0.1616	DPM3/MAGT1/VCP/UBE2J1/STT3A/FUT8/UBE2G2	7
BP	GO:0043276	anoikis	7/2112	34/18670	0.08252	0.2237	0.1616	NTRK2/SIK1/CEACAM5/NOTCH1/PIK3CA/PDK4/IKBKG	7
BP	GO:1904030	negative regulation of cyclin-dependent protein kinase activity	7/2112	34/18670	0.08252	0.2237	0.1616	CDKN2C/TNFAIP3/CDKN1C/PLK1/HEXIM1/IPO7/CEBPA	7
BP	GO:0090288	negative regulation of cellular response to growth factor stimulus	25/2112	166/18670	0.08333	0.2258	0.1631	CXCL13/SFRP1/SKI/HTRA1/SULF1/ADAMTSL2/TWSG1/TGFBR3/DCN/GLG1/CHST11/PMEPA1/SMAD3/TNMD/LDLRAD4/NOTCH1/NBL1/TOB1/CHRDL1/TGFB3/HIPK2/FSTL3/CFLAR/TP53/CASK	25
BP	GO:0042278	purine nucleoside metabolic process	13/2112	76/18670	0.08366	0.2263	0.1635	AMPD3/NT5E/ADK/NME7/ADA/AHCYL1/MACROD1/MOCS2/PNP/MBIP/AHCYL2/NME4/CASK	13
BP	GO:0042310	vasoconstriction	13/2112	76/18670	0.08366	0.2263	0.1635	ICAM1/COMP/HTR2B/EGFR/PER2/HTR2A/HRH1/LEP/AGTR1/ATP1A2/SLC8A1/EDNRB/CD38	13
BP	GO:0046902	regulation of mitochondrial membrane permeability	13/2112	76/18670	0.08366	0.2263	0.1635	TFDP2/GZMB/BID/EYA2/TMEM14A/BAK1/TP63/PMAIP1/SLC25A5/TP53BP2/TP53/BNIP3L/MOAP1	13
BP	GO:0072088	nephron epithelium morphogenesis	13/2112	76/18670	0.08366	0.2263	0.1635	BMP4/STAT1/SOX9/GLI3/SIX1/SIX2/FGF2/PBX1/DCHS1/FAT4/PKD2/HOXA11/AHI1	13
BP	GO:0009119	ribonucleoside metabolic process	16/2112	98/18670	0.08383	0.2264	0.1636	AMPD3/NT5E/UPP1/ADK/APOBEC3G/APOBEC3B/NME7/ADA/AHCYL1/MOCS2/PNP/MBIP/AHCYL2/ENTPD4/NME4/CASK	16
BP	GO:0072163	mesonephric epithelium development	16/2112	98/18670	0.08383	0.2264	0.1636	SFRP1/CRLF1/BMP4/SOX9/GLI3/FOXC1/SIX1/SIX2/FGF2/PBX1/DCHS1/SMAD3/FAT4/PKD2/CAT/HOXA11	16
BP	GO:0072164	mesonephric tubule development	16/2112	98/18670	0.08383	0.2264	0.1636	SFRP1/CRLF1/BMP4/SOX9/GLI3/FOXC1/SIX1/SIX2/FGF2/PBX1/DCHS1/SMAD3/FAT4/PKD2/CAT/HOXA11	16
BP	GO:0002223	stimulatory C-type lectin receptor signaling pathway	18/2112	113/18670	0.08443	0.228	0.1647	PSMB9/RELB/PSMB8/CLEC10A/PSMB10/SKP1/MALT1/PSME1/CREBBP/PLCG2/CLEC4E/NFKB1/ICAM3/CLEC4A/PAK1/SYK/IKBKG/LYN	18
BP	GO:0031668	cellular response to extracellular stimulus	38/2112	268/18670	0.08448	0.228	0.1647	SFRP1/PTPRC/PENK/GABARAPL1/SIPA1/IL15/ITGA4/PIM1/AKR1C3/UPP1/AXL/CBS/KANK2/ICAM1/TRIM24/GABARAPL2/DAP/SIK1/PCK1/PTN/SOD1/PMAIP1/FOXO1/LEP/HIGD1A/DSC2/FOSL1/PDK4/HFE/BCL11A/RYR3/CYBA/PRKD1/SESN1/LYN/TP53/P2RY4/TXN2	38
BP	GO:0010038	response to metal ion	50/2112	364/18670	0.08472	0.2286	0.1651	CPNE3/TNFRSF11B/PENK/NQO1/AKR1C3/PPP2CA/PPP3CA/NFE2L1/TCIRG1/CYBRD1/PAM/AQP9/ICAM1/EGFR/NPC1/SEC31A/CDK1/AHCYL1/S100A13/NLGN1/PLN/SOD1/PPP2CB/TRPC1/CA2/ECT2/GDI1/CCNB1/PPP1CA/TFAP2A/SYT17/CCND1/PARP1/SLC25A23/HFE/BACE1/MAOB/RYR3/GUCA1A/FABP4/CEBPA/IGFBP2/FSTL3/PKD2/CAT/NCF1/ERCC1/ALAD/GSN/MT1X	50
BP	GO:0006310	DNA recombination	41/2112	292/18670	0.08504	0.2293	0.1657	PTPRC/BCL11B/IL27RA/IL7R/BATF/NUCKS1/ZNF365/SMC6/CD40/TFRC/UBE2B/CDC45/BLM/WAS/TCF7/TBX21/MCM5/CD40LG/REV3L/PPP4C/TOP2A/RNF138/FEN1/LEF1/RMI1/TIMELESS/CDC7/MCM2/PARP1/ACTR8/NIPBL/REC8/KPNA2/MORF4L1/MCM4/RAD51AP1/ERCC1/THOC1/SMCHD1/TRIP13/ACTR2	41
BP	GO:0071300	cellular response to retinoic acid	12/2112	69/18670	0.08516	0.2295	0.1658	EPHA3/WNT5B/SOX9/YAP1/PCK1/NDUFA13/FZD4/FZD7/LEP/TESC/LYN/BRINP1	12
BP	GO:0006458	'de novo' protein folding	8/2112	41/18670	0.08547	0.2298	0.166	CD74/GAK/HSPA6/DNAJC7/HSPA1L/DNAJB4/DNAJC2/ST13	8
BP	GO:0019985	translesion synthesis	8/2112	41/18670	0.08547	0.2298	0.166	DTL/UBE2L6/REV3L/RFC3/VCP/POLE2/USP10/ISG15	8
BP	GO:0042572	retinol metabolic process	8/2112	41/18670	0.08547	0.2298	0.166	AKR1C3/ADH1C/AKR1B1/DHRS3/RBP4/ADH1B/DHRS9/RETSAT	8
BP	GO:0045005	DNA-dependent DNA replication maintenance of fidelity	8/2112	41/18670	0.08547	0.2298	0.166	NUCKS1/ZNF365/BLM/ATRX/DONSON/TIMELESS/THOC1/SETMAR	8
BP	GO:0050434	positive regulation of viral transcription	8/2112	41/18670	0.08547	0.2298	0.166	NUCKS1/CHD1/CCNT1/SP1/LEF1/GTF2F1/POLR2L/RSF1	8
BP	GO:1903170	negative regulation of calcium ion transmembrane transport	8/2112	41/18670	0.08547	0.2298	0.166	SRI/DYSF/GEM/PLN/ATP1A2/PKD2/GSTO1/GSTM2	8
BP	GO:0006338	chromatin remodeling	27/2112	182/18670	0.08578	0.2304	0.1665	SOX9/CHD1/BAZ1A/HDAC4/SMARCA1/BPTF/HJURP/TPR/SMARCD3/TP63/SMARCC2/SMARCA2/ATRX/NPM3/SMARCD1/PAK1/CHD4/ACTR8/HELLS/JARID2/SCMH1/RSF1/RB1/HMGA1/CENPM/EZH1/SMCHD1	27
BP	GO:0009166	nucleotide catabolic process	27/2112	182/18670	0.08578	0.2304	0.1665	AMPD3/IGF1/NT5E/ZBTB20/UPP1/SLC2A6/CBFA2T3/NUP93/HDAC4/HK3/ADA/ALDOC/PDE1A/TPR/ACAT1/NUP160/HTR2A/VCP/IFNG/ARNT/NUDT11/PNP/ENTPD4/NUP88/HINT1/NUP50/TP53	27
BP	GO:0014909	smooth muscle cell migration	15/2112	91/18670	0.08623	0.2314	0.1672	CCL5/IGFBP5/IGF1/LPAR1/BMPR1A/PDGFD/HDAC4/PLAT/NOX4/PARVA/PAK1/ADIPOQ/P2RY6/FGF9/PRKG1	15
BP	GO:0010830	regulation of myotube differentiation	11/2112	62/18670	0.0863	0.2314	0.1672	CXCL9/IL4R/HDAC4/SHOX2/CXCL10/SIK1/CD53/CEACAM5/BHLHE41/NOTCH1/CFLAR	11
BP	GO:0060393	regulation of pathway-restricted SMAD protein phosphorylation	11/2112	62/18670	0.0863	0.2314	0.1672	GDF5/BMP4/INHBA/BMPR1A/TWSG1/PMEPA1/LDLRAD4/ACVR1/HFE/TGFB3/TTK	11
BP	GO:0071326	cellular response to monosaccharide stimulus	21/2112	136/18670	0.0863	0.2314	0.1672	ZBTB20/SRI/OXCT1/PPP3CA/ICAM1/KLF7/MPC2/PCK1/LRP5/NOX4/EFNA5/LEP/PIK3CA/STX4/SYBU/FOXO3/CYBA/RAB11FIP2/SLC2A5/ZNF236/GPR27	21
BP	GO:0010107	potassium ion import	9/2112	48/18670	0.08675	0.232	0.1676	KCNJ5/KCNJ15/KCNJ2/ATP1B1/KCNJ8/ATP1A2/SLC12A2/SLC12A8/SLC12A7	9
BP	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	9/2112	48/18670	0.08675	0.232	0.1676	GDF5/BMP4/INHBA/BMPR1A/TWSG1/ACVR1/HFE/TGFB3/TTK	9
BP	GO:0030850	prostate gland development	9/2112	48/18670	0.08675	0.232	0.1676	SFRP1/BMP4/SOX9/GLI3/AR/SULF1/TP63/NOTCH1/EAF2	9
BP	GO:0044764	multi-organism cellular process	9/2112	48/18670	0.08675	0.232	0.1676	CCR5/BIRC3/CXCR4/IRF7/IFIH1/TSPAN6/DDX58/DDX60/KRT6A	9
BP	GO:0072604	interleukin-6 secretion	9/2112	48/18670	0.08675	0.232	0.1676	IL27RA/TLR8/CD200/LGALS9/IFIH1/DDX58/LEP/PTPN22/IL1B	9
BP	GO:2000059	negative regulation of ubiquitin-dependent protein catabolic process	9/2112	48/18670	0.08675	0.232	0.1676	HSP90AB1/HFE/HIPK2/BAG5/WAC/PBK/USP7/CAMLG/PML	9
BP	GO:0002011	morphogenesis of an epithelial sheet	10/2112	55/18670	0.0869	0.2322	0.1678	LRP6/PDPN/HBEGF/DAG1/NOTCH1/MEGF8/MPP5/DVL1/MMP12/ARHGAP12	10
BP	GO:0032781	positive regulation of ATPase activity	10/2112	55/18670	0.0869	0.2322	0.1678	PFN2/GABARAPL2/NCAPH/ATP1B1/TOR1AIP1/RGN/PLSCR1/DNAJB4/SETMAR/PFN1	10
BP	GO:0021510	spinal cord development	17/2112	106/18670	0.0872	0.2328	0.1682	ZIC1/HOXC10/PBX3/GLI3/NFE2L1/GATA2/PTN/ZPR1/PTPRS/TCTN1/DAAM2/NOTCH1/HOXD10/TULP3/PKD2/RFX4/GDPD5	17
BP	GO:1901606	alpha-amino acid catabolic process	17/2112	106/18670	0.0872	0.2328	0.1682	FAH/CDO1/IDO1/ALDH7A1/KYNU/ALDH6A1/CBS/PCBD1/OAT/DDAH2/MCCC1/ASPA/ACAT1/HPD/MAT1A/KMO/AASS	17
BP	GO:0035051	cardiocyte differentiation	25/2112	167/18670	0.08795	0.2346	0.1695	SGCB/BMP4/IGF1/MYH10/CBY1/EGFR/TGFBR3/CDK1/SIK1/SORBS2/PDLIM5/NOX4/SGCD/FZD7/NOTCH1/CCNB1/HEY2/SLC8A1/PAK1/ACVR1/AKAP13/MYH11/LMNA/TENM4/ALPK3	25
BP	GO:1901568	fatty acid derivative metabolic process	25/2112	167/18670	0.08795	0.2346	0.1695	LTC4S/AKR1C3/OXCT1/TLR2/CD74/ACSS3/ACAT1/HPGDS/PLA2G4C/GPX4/HSD17B12/BDH2/BDH1/SYK/FABP5/MAPKAPK2/PTGS1/ELOVL4/SLC27A5/ELOVL2/ACSL5/IL1B/EPHX2/ALOX5/ELOVL5	25
BP	GO:0060041	retina development in camera-type eye	22/2112	144/18670	0.08822	0.2352	0.1699	LRP6/MYH10/SOX9/NTRK2/SKI/CDON/TCIRG1/RPL24/SMARCD3/PTN/LRP5/FZD4/RBP4/IRX5/TFAP2A/ZHX2/HIPK2/DIO3/MERTK/ROM1/NPHP4/AHI1	22
BP	GO:0010507	negative regulation of autophagy	14/2112	84/18670	0.08855	0.2356	0.1703	RASIP1/GOLGA2/HTR2B/DAP/NPC1/HGF/FEZ1/LEP/PIK3CA/IL10RA/PINK1/PTPN22/FEZ2/TP53	14
BP	GO:0048144	fibroblast proliferation	14/2112	84/18670	0.08855	0.2356	0.1703	SFRP1/IGF1/DDR2/BTC/SKI/CD74/PDGFD/NDUFS4/EGFR/SPHK1/CCNA2/CCNB1/TP53/PML	14
BP	GO:0001516	prostaglandin biosynthetic process	6/2112	28/18670	0.08903	0.2356	0.1703	AKR1C3/CD74/HPGDS/FABP5/PTGS1/IL1B	6
BP	GO:0001702	gastrulation with mouth forming second	6/2112	28/18670	0.08903	0.2356	0.1703	LRP6/LRP5/UGDH/ACVR1/MEGF8/TENM4	6
BP	GO:0009074	aromatic amino acid family catabolic process	6/2112	28/18670	0.08903	0.2356	0.1703	FAH/IDO1/KYNU/PCBD1/HPD/KMO	6
BP	GO:0010894	negative regulation of steroid biosynthetic process	6/2112	28/18670	0.08903	0.2356	0.1703	ERLIN1/SOD1/NFKB1/ERLIN2/GFI1/DKK3	6
BP	GO:0018146	keratan sulfate biosynthetic process	6/2112	28/18670	0.08903	0.2356	0.1703	PRELP/FMOD/OGN/LUM/B3GNT2/B4GALT2	6
BP	GO:0032770	positive regulation of monooxygenase activity	6/2112	28/18670	0.08903	0.2356	0.1703	GCH1/HTR2B/IFNG/NOD1/NPR3/IL1B	6
BP	GO:0033688	regulation of osteoblast proliferation	6/2112	28/18670	0.08903	0.2356	0.1703	NELL1/SFRP1/SMAD3/NPR3/ATRAID/ITGAV	6
BP	GO:0034368	protein-lipid complex remodeling	6/2112	28/18670	0.08903	0.2356	0.1703	ABCG1/LIPG/AGTR1/CETP/LIPC/PLA2G7	6
BP	GO:0034369	plasma lipoprotein particle remodeling	6/2112	28/18670	0.08903	0.2356	0.1703	ABCG1/LIPG/AGTR1/CETP/LIPC/PLA2G7	6
BP	GO:0042634	regulation of hair cycle	6/2112	28/18670	0.08903	0.2356	0.1703	FA2H/ARNTL/NIPBL/FST/FERMT1/SPINK5	6
BP	GO:0045408	regulation of interleukin-6 biosynthetic process	6/2112	28/18670	0.08903	0.2356	0.1703	CD74/CLEC7A/SYK/INPP5D/TLR6/IL1B	6
BP	GO:0046457	prostanoid biosynthetic process	6/2112	28/18670	0.08903	0.2356	0.1703	AKR1C3/CD74/HPGDS/FABP5/PTGS1/IL1B	6
BP	GO:0051984	positive regulation of chromosome segregation	6/2112	28/18670	0.08903	0.2356	0.1703	SMC6/DLGAP5/FEN1/CCNB1/NIPBL/RB1	6
BP	GO:0052312	modulation of transcription in other organism involved in symbiotic interaction	6/2112	28/18670	0.08903	0.2356	0.1703	CCL5/NUCKS1/CHD1/CCNT1/SP1/LEF1	6
BP	GO:1902932	positive regulation of alcohol biosynthetic process	6/2112	28/18670	0.08903	0.2356	0.1703	ABCG1/HRH1/IFNG/P2RY6/PTH1R/IL1B	6
BP	GO:0045732	positive regulation of protein catabolic process	31/2112	214/18670	0.08918	0.2359	0.1705	TNFAIP3/CLU/TNFRSF1B/SOX9/DTL/AREL1/CBFA2T3/ADAM8/CTSC/PLK1/CHFR/BARD1/BAG2/NDUFA13/FOXO1/EDEM1/PLK2/VCP/MYLIP/IFNG/RGN/DACT1/RNF19B/CUL4B/CEBPA/DVL1/CD81/EDEM2/AURKA/RNF14/IL1B	31
BP	GO:0001678	cellular glucose homeostasis	23/2112	152/18670	0.08992	0.2378	0.1718	PIK3R1/ZBTB20/SRI/NUCKS1/OXCT1/PPP3CA/ICAM1/HK3/KLF7/MPC2/PCK1/LRP5/NOX4/FOXO1/EFNA5/PIK3CA/STX4/SYBU/FOXO3/CYBA/RAB11FIP2/ZNF236/GPR27	23
BP	GO:0015749	monosaccharide transmembrane transport	18/2112	114/18670	0.09016	0.2383	0.1722	ENPP1/PID1/PIK3R1/IGF1/PRKCB/SLC2A6/SLC2A3/PTPN11/SLC2A10/LEP/SLC5A3/ADIPOQ/FABP5/SORBS1/CLIP3/SLC23A2/SLC2A5/IL1B	18
BP	GO:0038061	NIK/NF-kappaB signaling	27/2112	183/18670	0.09027	0.2384	0.1723	PSMB9/RELB/PSMB8/BIRC3/PSMB10/CCL19/NFKB2/SKP1/TLR2/LGALS9/NOD2/MALT1/PSME1/EGFR/TSPAN6/SPHK1/CD27/NFKBIA/PPP4C/TRIP6/PTPN22/IL18/AKIP1/NOD1/TLR6/IL1B/NLRP3	27
BP	GO:0050770	regulation of axonogenesis	27/2112	183/18670	0.09027	0.2384	0.1723	SEMA4A/SEMA4D/NTRK2/SEMA3A/TRAK2/SHOX2/TUBB2B/FGF13/TRPV2/CDH2/RYK/PTPRS/SEMA3F/EFNA5/CHN1/GDI1/PAK1/CTTN/CHODL/MAP1B/ARHGAP4/MEGF8/DPYSL2/SEMA4F/SEMA3E/SEMA6B/FEZF2	27
BP	GO:0048332	mesoderm morphogenesis	13/2112	77/18670	0.09074	0.2395	0.173	BMP4/FOXC1/INHBA/EYA2/BMPR1A/WLS/SIX2/TWSG1/LEF1/SMAD3/ACVR1/EXT2/HOXA11	13
BP	GO:1901224	positive regulation of NIK/NF-kappaB signaling	13/2112	77/18670	0.09074	0.2395	0.173	CCL19/TLR2/LGALS9/NOD2/MALT1/EGFR/SPHK1/CD27/TRIP6/IL18/NOD1/TLR6/IL1B	13
BP	GO:0001935	endothelial cell proliferation	28/2112	191/18670	0.09123	0.2406	0.1739	BMP4/STAT1/ITGA4/ITGB1BP1/SULF1/DYSF/PRKD2/HTR2B/SCG2/GATA2/FGF2/THBS4/SP1/PPP1R16B/TNMD/LEP/AGTR1/ARNT/PRL/APLNR/AKT3/CYBA/VEGFB/PRKD1/ANG/KDR/CCL2/THAP1	28
BP	GO:0009144	purine nucleoside triphosphate metabolic process	47/2112	342/18670	0.09161	0.2415	0.1745	ENPP1/PID1/AMPD3/IGF1/ZBTB20/NDUFC1/BID/ADK/NDUFS2/SLC2A6/CBFA2T3/COX7A1/NUP93/HDAC4/NDUFS4/HK3/NME7/ADA/ALDOC/TPR/CDK1/NDUFA13/NUP160/AK1/HTR2A/ATP1B1/MOCS2/VCP/IFNG/ARNT/CCNB1/ATP1A2/MECP2/MBIP/PARP1/SLC25A23/PINK1/NDUFA9/NME4/NUP88/SDHA/NDUFB6/NUP50/TP53/ATP6V1B2/NDUFA4/COX7A2	47
BP	GO:0015850	organic hydroxy compound transport	37/2112	262/18670	0.09164	0.2415	0.1745	LRP6/CLU/ABCG1/AQP9/CD36/SLC18A2/AKR1C1/NPC1/TAC1/NFKBIA/NFKB1/HTR2A/PTPN11/RBP4/LIPG/LEP/STARD5/AGTR1/MECP2/SLC5A3/SYT17/ADIPOQ/SYK/CETP/PINK1/MAOB/SNCG/NR1H3/RALBP1/OSBPL1A/SLC27A5/OSBPL9/REN/SLCO1C1/LIPC/LILRB1/SOAT2	37
BP	GO:0016052	carbohydrate catabolic process	29/2112	199/18670	0.09206	0.2415	0.1745	GK/IGF1/GALT/ZBTB20/SLC2A6/CBFA2T3/NUP93/HDAC4/HK3/ALDOC/TPR/PHKB/LRP5/NUP160/HTR2A/PGD/IFNG/ARNT/PPP1CA/AOAH/SCARB2/MAN2B1/NUP88/FUT8/MANBA/NUP50/TP53/TKTL1/FUT4	29
BP	GO:0032720	negative regulation of tumor necrosis factor production	12/2112	70/18670	0.09273	0.2415	0.1745	TNFAIP3/IL27RA/IGF1/SLAMF1/AXL/LGALS9/PTPN6/GPR18/CLEC4A/ADIPOQ/PTPN22/LILRB1	12
BP	GO:2001259	positive regulation of cation channel activity	12/2112	70/18670	0.09273	0.2415	0.1745	CCR2/CACNA2D1/ANK2/PLCG2/IFNG/FGF14/P2RY6/PINK1/PKD2/GSTO1/GSTM2/CCL2	12
BP	GO:0002064	epithelial cell development	30/2112	207/18670	0.09279	0.2415	0.1745	BMP4/BCL11B/WNT5B/CXCR4/SOX9/TMOD1/GSTM3/AR/ICAM1/ARHGEF26/YIPF6/SPINT2/MAGI2/PPP1R16B/TP63/SOD1/PTPRS/TNMD/ATRX/NOTCH1/ARNTL/PECAM1/ADIPOQ/TYMS/ABI2/GPR4/IL1B/CDH5/HOXA5/CRYGB	30
BP	GO:0034284	response to monosaccharide	30/2112	207/18670	0.09279	0.2415	0.1745	ZBTB20/SRI/OXCT1/PPP3CA/ICAM1/KLF7/MPC2/TCF7L2/PCK1/LRP5/NOX4/RMI1/EFNA5/LEP/PIK3CA/SLC8A1/ADIPOQ/STX4/VAMP2/NDUFA9/SYBU/FOXO3/ENSA/CYBA/CAT/RAB11FIP2/SLC2A5/ZNF236/GPR27/TXN2	30
BP	GO:0009314	response to radiation	60/2112	448/18670	0.09356	0.2415	0.1745	PIK3R1/SFRP1/PTPRC/SCARA3/PENK/DTL/NUCKS1/MFAP4/ICAM1/CRYAB/YAP1/CXCL10/MEIS2/EGFR/UBE2B/BLM/CREBBP/OPN3/SLC1A3/SIK1/BAK1/ADIRF/PER2/PTN/NOX4/MAPK13/FEN1/NET1/HYAL1/HRH1/ECT2/PPP1CA/ATP1A2/MECP2/CCL7/CCND1/PARP1/NIPBL/BACE1/ELOVL4/PER3/AURKB/CYBA/SDF4/GUCA1A/METAP2/CUL4B/RAD51AP1/CAT/DYNLRB1/ERCC1/ALAD/PBK/TP53/PLEKHB1/TOPBP1/NPHP4/PML/B4GALT2/GTF2H5	60
BP	GO:0000266	mitochondrial fission	7/2112	35/18670	0.09357	0.2415	0.1745	MX2/DCN/TMEM135/PINK1/KDR/MX1/INF2	7
BP	GO:0021955	central nervous system neuron axonogenesis	7/2112	35/18670	0.09357	0.2415	0.1745	TSKU/NFIB/EPHB1/TCTN1/SCN1B/HSP90AB1/DCLK1	7
BP	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	7/2112	35/18670	0.09357	0.2415	0.1745	HSP90AB1/HFE/BAG5/WAC/PBK/USP7/CAMLG	7
BP	GO:0032689	negative regulation of interferon-gamma production	7/2112	35/18670	0.09357	0.2415	0.1745	XCL1/INHBA/AXL/LGALS9/CD96/PDCD1LG2/LILRB1	7
BP	GO:0045070	positive regulation of viral genome replication	7/2112	35/18670	0.09357	0.2415	0.1745	CCL5/NUCKS1/SRPK1/TOP2A/NOTCH1/ADAR/TRIM38	7
BP	GO:0060338	regulation of type I interferon-mediated signaling pathway	7/2112	35/18670	0.09357	0.2415	0.1745	PTPN2/IRF7/PTPN6/PTPN11/ADAR/HSP90AB1/MMP12	7
BP	GO:1903539	protein localization to postsynaptic membrane	7/2112	35/18670	0.09357	0.2415	0.1745	RAB8A/DAG1/CLSTN1/ADAM22/GPC4/LGI1/ADAM10	7
BP	GO:0001936	regulation of endothelial cell proliferation	26/2112	176/18670	0.0939	0.2415	0.1745	BMP4/STAT1/ITGA4/SULF1/DYSF/PRKD2/HTR2B/SCG2/GATA2/FGF2/THBS4/SP1/PPP1R16B/TNMD/LEP/AGTR1/ARNT/PRL/APLNR/AKT3/CYBA/VEGFB/PRKD1/ANG/KDR/CCL2	26
BP	GO:0009408	response to heat	26/2112	176/18670	0.0939	0.2415	0.1745	IGF1/IER5/CRYAB/NUP93/MICB/CXCL10/TFEC/CREBBP/HSPA6/TRPV2/TPR/BAG2/NUP160/SOD1/VCP/HSP90AB1/DNAJC7/MAPKAPK2/LYN/HSPA1L/NUP88/BAG5/DNAJB4/NUP50/DNAJC2/PSIP1	26
BP	GO:0007062	sister chromatid cohesion	11/2112	63/18670	0.0944	0.2415	0.1745	BUB1/PLK1/STAG2/BUB1B/FEN1/ATRX/STAG3/NIPBL/REC8/RB1/CDC20	11
BP	GO:0031571	mitotic G1 DNA damage checkpoint	11/2112	63/18670	0.0944	0.2415	0.1745	TFDP2/E2F8/CDK1/PLK2/CCNB1/CCND1/PRMT1/PCBP4/TP53/AURKA/PML	11
BP	GO:0031646	positive regulation of neurological system process	11/2112	63/18670	0.0944	0.2415	0.1745	WASF3/TNFRSF1B/CST7/PARD3/DAG1/HGF/NLGN1/ITGAX/DVL1/TENM4/RNF10	11
BP	GO:0044819	mitotic G1/S transition checkpoint	11/2112	63/18670	0.0944	0.2415	0.1745	TFDP2/E2F8/CDK1/PLK2/CCNB1/CCND1/PRMT1/PCBP4/TP53/AURKA/PML	11
BP	GO:0046686	response to cadmium ion	11/2112	63/18670	0.0944	0.2415	0.1745	AKR1C3/EGFR/NPC1/CDK1/SOD1/CAT/NCF1/ERCC1/ALAD/GSN/MT1X	11
BP	GO:1903320	regulation of protein modification by small protein conjugation or removal	33/2112	231/18670	0.09441	0.2415	0.1745	TNFAIP3/BIRC3/ANGPT1/UBE2C/NOD2/MALT1/DYSF/MAD2L1/GOLGA2/PLK1/NMI/HDAC4/RIPK2/CDC14B/FANCI/CHFR/SPHK1/BAG2/PER2/TRIM21/UBE2D1/VCP/ARNT/HSP90AB1/FBXO5/PINK1/PTPN22/IVNS1ABP/CDC20/NDFIP1/BAG5/CAMLG/ISG15	33
BP	GO:0001820	serotonin secretion	3/2112	10/18670	0.0945	0.2415	0.1745	SYK/MAOB/LILRB1	3
BP	GO:0002713	negative regulation of B cell mediated immunity	3/2112	10/18670	0.0945	0.2415	0.1745	PTPN6/CR1/THOC1	3
BP	GO:0002890	negative regulation of immunoglobulin mediated immune response	3/2112	10/18670	0.0945	0.2415	0.1745	PTPN6/CR1/THOC1	3
BP	GO:0003376	sphingosine-1-phosphate receptor signaling pathway	3/2112	10/18670	0.0945	0.2415	0.1745	SPHK1/S1PR1/S1PR4	3
BP	GO:0006569	tryptophan catabolic process	3/2112	10/18670	0.0945	0.2415	0.1745	IDO1/KYNU/KMO	3
BP	GO:0007084	mitotic nuclear envelope reassembly	3/2112	10/18670	0.0945	0.2415	0.1745	PPP2CA/VRK1/LMNA	3
BP	GO:0007135	meiosis II	3/2112	10/18670	0.0945	0.2415	0.1745	BUB1/BUB1B/DAZL	3
BP	GO:0009157	deoxyribonucleoside monophosphate biosynthetic process	3/2112	10/18670	0.0945	0.2415	0.1745	TYMS/TK2/TK1	3
BP	GO:0010944	negative regulation of transcription by competitive promoter binding	3/2112	10/18670	0.0945	0.2415	0.1745	BHLHE41/TFAP2A/KDM2A	3
BP	GO:0014877	response to muscle inactivity involved in regulation of muscle adaptation	3/2112	10/18670	0.0945	0.2415	0.1745	SGCA/HDAC4/DAG1	3
BP	GO:0014894	response to denervation involved in regulation of muscle adaptation	3/2112	10/18670	0.0945	0.2415	0.1745	SGCA/HDAC4/DAG1	3
BP	GO:0019062	virion attachment to host cell	3/2112	10/18670	0.0945	0.2415	0.1745	ICAM1/HSP90AB1/CD81	3
BP	GO:0021877	forebrain neuron fate commitment	3/2112	10/18670	0.0945	0.2415	0.1745	BCL11B/GATA2/FEZF2	3
BP	GO:0032353	negative regulation of hormone biosynthetic process	3/2112	10/18670	0.0945	0.2415	0.1745	NFKB1/GFI1/DKK3	3
BP	GO:0032463	negative regulation of protein homooligomerization	3/2112	10/18670	0.0945	0.2415	0.1745	CLU/CRYAB/CRBN	3
BP	GO:0032875	regulation of DNA endoreduplication	3/2112	10/18670	0.0945	0.2415	0.1745	E2F8/STAG2/FBXO5	3
BP	GO:0034350	regulation of glial cell apoptotic process	3/2112	10/18670	0.0945	0.2415	0.1745	PRKCH/AKAP12/CCL2	3
BP	GO:0035768	endothelial cell chemotaxis to fibroblast growth factor	3/2112	10/18670	0.0945	0.2415	0.1745	CXCL13/FGF18/FGF2	3
BP	GO:0039530	MDA-5 signaling pathway	3/2112	10/18670	0.0945	0.2415	0.1745	IRF7/IFIH1/DDX60	3
BP	GO:0042436	indole-containing compound catabolic process	3/2112	10/18670	0.0945	0.2415	0.1745	IDO1/KYNU/KMO	3
BP	GO:0044557	relaxation of smooth muscle	3/2112	10/18670	0.0945	0.2415	0.1745	SOD1/SLC8A1/PRKG1	3
BP	GO:0046218	indolalkylamine catabolic process	3/2112	10/18670	0.0945	0.2415	0.1745	IDO1/KYNU/KMO	3
BP	GO:0046322	negative regulation of fatty acid oxidation	3/2112	10/18670	0.0945	0.2415	0.1745	ACADVL/ACACB/ACADL	3
BP	GO:0046532	regulation of photoreceptor cell differentiation	3/2112	10/18670	0.0945	0.2415	0.1745	SOX9/NOTCH1/DIO3	3
BP	GO:0048262	determination of dorsal/ventral asymmetry	3/2112	10/18670	0.0945	0.2415	0.1745	NBL1/ACVR1/DDIT3	3
BP	GO:0048304	positive regulation of isotype switching to IgG isotypes	3/2112	10/18670	0.0945	0.2415	0.1745	PTPRC/CD40/TBX21	3
BP	GO:0050861	positive regulation of B cell receptor signaling pathway	3/2112	10/18670	0.0945	0.2415	0.1745	PRKCH/PRKCB/CD81	3
BP	GO:0051014	actin filament severing	3/2112	10/18670	0.0945	0.2415	0.1745	GMFG/DSTN/GSN	3
BP	GO:0051409	response to nitrosative stress	3/2112	10/18670	0.0945	0.2415	0.1745	DUSP6/ADH5/DDIT3	3
BP	GO:0052646	alditol phosphate metabolic process	3/2112	10/18670	0.0945	0.2415	0.1745	GK/ABHD6/GPD1L	3
BP	GO:0060033	anatomical structure regression	3/2112	10/18670	0.0945	0.2415	0.1745	BMPR1A/LEF1/SPI1	3
BP	GO:0060281	regulation of oocyte development	3/2112	10/18670	0.0945	0.2415	0.1745	IGF1/NPR2/AURKA	3
BP	GO:0060768	regulation of epithelial cell proliferation involved in prostate gland development	3/2112	10/18670	0.0945	0.2415	0.1745	AR/NOTCH1/EAF2	3
BP	GO:0061983	meiosis II cell cycle process	3/2112	10/18670	0.0945	0.2415	0.1745	BUB1/BUB1B/DAZL	3
BP	GO:0070091	glucagon secretion	3/2112	10/18670	0.0945	0.2415	0.1745	PASK/LEP/IL6	3
BP	GO:0070391	response to lipoteichoic acid	3/2112	10/18670	0.0945	0.2415	0.1745	TLR2/CD36/RIPK2	3
BP	GO:0071223	cellular response to lipoteichoic acid	3/2112	10/18670	0.0945	0.2415	0.1745	TLR2/CD36/RIPK2	3
BP	GO:0071281	cellular response to iron ion	3/2112	10/18670	0.0945	0.2415	0.1745	CCNB1/TFAP2A/HFE	3
BP	GO:0071313	cellular response to caffeine	3/2112	10/18670	0.0945	0.2415	0.1745	SLC8A1/RYR3/GSTM2	3
BP	GO:0071670	smooth muscle cell chemotaxis	3/2112	10/18670	0.0945	0.2415	0.1745	LPAR1/PDGFD/PARVA	3
BP	GO:0072015	glomerular visceral epithelial cell development	3/2112	10/18670	0.0945	0.2415	0.1745	BMP4/MAGI2/ADIPOQ	3
BP	GO:0072124	regulation of glomerular mesangial cell proliferation	3/2112	10/18670	0.0945	0.2415	0.1745	BMP4/PDGFD/CFLAR	3
BP	GO:0098917	retrograde trans-synaptic signaling	3/2112	10/18670	0.0945	0.2415	0.1745	DAG1/NLGN1/FABP5	3
BP	GO:0110096	cellular response to aldehyde	3/2112	10/18670	0.0945	0.2415	0.1745	AKR1B1/ESD/ADH5	3
BP	GO:0140052	cellular response to oxidised low-density lipoprotein particle stimulus	3/2112	10/18670	0.0945	0.2415	0.1745	MYD88/CD36/TLR6	3
BP	GO:1901725	regulation of histone deacetylase activity	3/2112	10/18670	0.0945	0.2415	0.1745	PRKD2/PINK1/PRKD1	3
BP	GO:1903789	regulation of amino acid transmembrane transport	3/2112	10/18670	0.0945	0.2415	0.1745	PER2/ARL6IP5/ATP1A2	3
BP	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA	3/2112	10/18670	0.0945	0.2415	0.1745	BMP4/EGFR/TP53	3
BP	GO:1905879	regulation of oogenesis	3/2112	10/18670	0.0945	0.2415	0.1745	IGF1/NPR2/AURKA	3
BP	GO:2000544	regulation of endothelial cell chemotaxis to fibroblast growth factor	3/2112	10/18670	0.0945	0.2415	0.1745	CXCL13/FGF18/FGF2	3
BP	GO:0002052	positive regulation of neuroblast proliferation	5/2112	22/18670	0.09481	0.2415	0.1745	ASPM/GLI3/SMARCD3/CX3CR1/NOTCH1	5
BP	GO:0007063	regulation of sister chromatid cohesion	5/2112	22/18670	0.09481	0.2415	0.1745	BUB1/FEN1/ATRX/NIPBL/RB1	5
BP	GO:0032656	regulation of interleukin-13 production	5/2112	22/18670	0.09481	0.2415	0.1745	IRF4/LGALS9/HLA-E/LEF1/NLRP3	5
BP	GO:0036119	response to platelet-derived growth factor	5/2112	22/18670	0.09481	0.2415	0.1745	PDGFD/CCNA2/PTN/HYAL1/FER	5
BP	GO:0044321	response to leptin	5/2112	22/18670	0.09481	0.2415	0.1745	PID1/CCNA2/LEP/CCND1/UGCG	5
BP	GO:0045723	positive regulation of fatty acid biosynthetic process	5/2112	22/18670	0.09481	0.2415	0.1745	CD74/RGN/NR1H3/IL1B/ELOVL5	5
BP	GO:0046628	positive regulation of insulin receptor signaling pathway	5/2112	22/18670	0.09481	0.2415	0.1745	NUCKS1/PTPN11/LEP/PAK1/SORBS1	5
BP	GO:0050765	negative regulation of phagocytosis	5/2112	22/18670	0.09481	0.2415	0.1745	CSK/TLR2/DYSF/ADIPOQ/ATG3	5
BP	GO:0060065	uterus development	5/2112	22/18670	0.09481	0.2415	0.1745	CDKN1C/HOXA10/RBP4/NIPBL/HOXA11	5
BP	GO:0060487	lung epithelial cell differentiation	5/2112	22/18670	0.09481	0.2415	0.1745	SOX9/YAP1/NFIB/HOXA5/THRA	5
BP	GO:0048639	positive regulation of developmental growth	27/2112	184/18670	0.09492	0.2417	0.1746	IGF1/CXCR4/SEMA4D/PIM1/SASH3/ZFPM2/BMPR1A/YAP1/FGF2/TGFBR3/TRPV2/GHR/CDK1/ACACB/EFNA5/NOTCH1/GDI1/LEP/CCNB1/HEY2/SYT17/PAK1/FGF9/NIPBL/MAP1B/MEGF8/DIO3	27
BP	GO:0009798	axis specification	14/2112	85/18670	0.09553	0.2426	0.1753	SFRP1/BMP4/LRP6/SKI/BMPR1A/WLS/SIX2/COBL/NOTCH1/HEY2/DDIT3/AURKA/STIL/AHI1	14
BP	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	10/2112	56/18670	0.09561	0.2426	0.1753	TFDP2/E2F8/CDK1/PLK2/CCNB1/PRMT1/PCBP4/TP53/AURKA/PML	10
BP	GO:0070936	protein K48-linked ubiquitination	10/2112	56/18670	0.09561	0.2426	0.1753	TNFAIP3/UBE2C/NMI/UBE2B/IFI27/UBE2D1/TRIM38/RNF146/UBE2E3/UBE2G2	10
BP	GO:0086002	cardiac muscle cell action potential involved in contraction	10/2112	56/18670	0.09561	0.2426	0.1753	CACNA2D1/ANK2/KCNJ5/KCNJ2/SCN1B/KCNJ8/DSC2/GJC1/SNTA1/GPD1L	10
BP	GO:0086065	cell communication involved in cardiac conduction	10/2112	56/18670	0.09561	0.2426	0.1753	SRI/CACNA2D1/ANK2/KCNJ5/ATP1B1/SCN1B/DSC2/ATP1A2/SLC8A1/GJC1	10
BP	GO:0010559	regulation of glycoprotein biosynthetic process	8/2112	42/18670	0.09564	0.2426	0.1753	IGF1/CCL19/IL15/CCR7/GOLGA2/HBEGF/CCL21/TCF7L2	8
BP	GO:0031057	negative regulation of histone modification	8/2112	42/18670	0.09564	0.2426	0.1753	SKI/UBE2B/TAF7/DNMT1/PAX5/MTF2/SPI1/JARID2	8
BP	GO:0032958	inositol phosphate biosynthetic process	8/2112	42/18670	0.09564	0.2426	0.1753	PLCE1/FGF2/PLCG2/PLEK/HRH1/P2RY6/PPIP5K1/PTH1R	8
BP	GO:1901031	regulation of response to reactive oxygen species	8/2112	42/18670	0.09564	0.2426	0.1753	GCH1/CD36/FBLN5/HGF/RGN/PINK1/FOXO3/SESN1	8
BP	GO:0008347	glial cell migration	9/2112	49/18670	0.09614	0.2435	0.1759	CCR2/NDN/GPR183/GLI3/IDH2/CSPG4/CX3CR1/CCL2/MBOAT7	9
BP	GO:0051445	regulation of meiotic cell cycle	9/2112	49/18670	0.09614	0.2435	0.1759	ASPM/NPR2/UBE2B/CDC25B/DAZL/FBXO5/TTK/CDC20/TRIP13	9
BP	GO:1903018	regulation of glycoprotein metabolic process	9/2112	49/18670	0.09614	0.2435	0.1759	IGF1/CCL19/IL15/CCR7/GOLGA2/HBEGF/CCL21/TCF7L2/PTX3	9
BP	GO:1904707	positive regulation of vascular smooth muscle cell proliferation	9/2112	49/18670	0.09614	0.2435	0.1759	IGFBP5/IGF1/BMPR1A/JAK2/FGF2/DNMT1/PAK1/P2RY6/FGF9	9
BP	GO:0030301	cholesterol transport	16/2112	100/18670	0.09644	0.2441	0.1764	LRP6/CLU/ABCG1/CD36/AKR1C1/NPC1/NFKBIA/NFKB1/LIPG/LEP/STARD5/ADIPOQ/CETP/NR1H3/LIPC/SOAT2	16
BP	GO:0035967	cellular response to topologically incorrect protein	24/2112	161/18670	0.09645	0.2441	0.1764	PIK3R1/ACADVL/PTPN2/EXTL2/TM7SF3/HSPA6/CXCL8/SEC31A/CREB3L2/BAK1/TSPYL2/EDEM1/KDELR3/VCP/GFPT1/FKBP14/CCND1/SDF2L1/DDIT3/LMNA/MBTPS2/HSPA1L/TATDN2/CCL2	24
BP	GO:0050728	negative regulation of inflammatory response	25/2112	169/18670	0.09769	0.2458	0.1776	SLAMF8/PTPRC/TNFAIP3/IGF1/NT5E/TNFRSF1B/CST7/CD200/PTPN2/ADA/HGF/SOD1/C5orf30/NFKB1/SMAD3/MFHAS1/PTGER4/ADIPOQ/NR1H3/FPR2/RB1/PBK/IL2RA/CDH5/NLRP3	25
BP	GO:0006487	protein N-linked glycosylation	13/2112	78/18670	0.09818	0.2458	0.1776	MGAT4C/B3GALNT1/ALG6/DPM3/MAGT1/VCP/GFPT1/MAN1C1/UBE2J1/STT3A/FUT8/GFPT2/UBE2G2	13
BP	GO:0072028	nephron morphogenesis	13/2112	78/18670	0.09818	0.2458	0.1776	BMP4/STAT1/SOX9/GLI3/SIX1/SIX2/FGF2/PBX1/DCHS1/FAT4/PKD2/HOXA11/AHI1	13
BP	GO:0000076	DNA replication checkpoint	4/2112	16/18670	0.09821	0.2458	0.1776	CDC45/TIMELESS/NAE1/TOPBP1	4
BP	GO:0002295	T-helper cell lineage commitment	4/2112	16/18670	0.09821	0.2458	0.1776	BATF/IRF4/TBX21/IL6	4
BP	GO:0002739	regulation of cytokine secretion involved in immune response	4/2112	16/18670	0.09821	0.2458	0.1776	TNFRSF1B/ANGPT1/TNFRSF14/LILRB1	4
BP	GO:0006837	serotonin transport	4/2112	16/18670	0.09821	0.2458	0.1776	SLC18A2/SYK/MAOB/LILRB1	4
BP	GO:0007567	parturition	4/2112	16/18670	0.09821	0.2458	0.1776	PLA2G4C/ARNTL/PTGFR/LDOC1	4
BP	GO:0010875	positive regulation of cholesterol efflux	4/2112	16/18670	0.09821	0.2458	0.1776	ABCG1/NFKBIA/ADIPOQ/NR1H3	4
BP	GO:0010919	regulation of inositol phosphate biosynthetic process	4/2112	16/18670	0.09821	0.2458	0.1776	PLEK/HRH1/P2RY6/PTH1R	4
BP	GO:0022038	corpus callosum development	4/2112	16/18670	0.09821	0.2458	0.1776	TSKU/LPAR1/RYK/PTPRS	4
BP	GO:0030952	establishment or maintenance of cytoskeleton polarity	4/2112	16/18670	0.09821	0.2458	0.1776	RHOF/KIF2C/RHOD/LMNA	4
BP	GO:0032695	negative regulation of interleukin-12 production	4/2112	16/18670	0.09821	0.2458	0.1776	SLAMF1/TLR8/NFKB1/LILRB1	4
BP	GO:0042448	progesterone metabolic process	4/2112	16/18670	0.09821	0.2458	0.1776	AKR1C3/AKR1C1/DHRS9/CYP46A1	4
BP	GO:0043031	negative regulation of macrophage activation	4/2112	16/18670	0.09821	0.2458	0.1776	PTPRC/CST7/CD200/NR1H3	4
BP	GO:0050711	negative regulation of interleukin-1 secretion	4/2112	16/18670	0.09821	0.2458	0.1776	TNFAIP3/SERPINB1/PML/NLRP3	4
BP	GO:0051444	negative regulation of ubiquitin-protein transferase activity	4/2112	16/18670	0.09821	0.2458	0.1776	MAD2L1/BAG2/FBXO5/BAG5	4
BP	GO:0051447	negative regulation of meiotic cell cycle	4/2112	16/18670	0.09821	0.2458	0.1776	NPR2/FBXO5/TTK/TRIP13	4
BP	GO:0060572	morphogenesis of an epithelial bud	4/2112	16/18670	0.09821	0.2458	0.1776	BMP4/AR/SULF1/TP63	4
BP	GO:0071380	cellular response to prostaglandin E stimulus	4/2112	16/18670	0.09821	0.2458	0.1776	SFRP1/PTGER4/P2RY6/P2RY4	4
BP	GO:0072189	ureter development	4/2112	16/18670	0.09821	0.2458	0.1776	BMP4/SOX9/SIX1/EMX2	4
BP	GO:0097067	cellular response to thyroid hormone stimulus	4/2112	16/18670	0.09821	0.2458	0.1776	SIX1/CTSL/CTSB/CTSH	4
BP	GO:0097091	synaptic vesicle clustering	4/2112	16/18670	0.09821	0.2458	0.1776	MAGI2/NLGN1/PCDH17/CDH2	4
BP	GO:1900451	positive regulation of glutamate receptor signaling pathway	4/2112	16/18670	0.09821	0.2458	0.1776	CCR2/IFNG/PINK1/CCL2	4
BP	GO:1990000	amyloid fibril formation	4/2112	16/18670	0.09821	0.2458	0.1776	CLU/CRYAB/CD36/GSN	4
BP	GO:2000846	regulation of corticosteroid hormone secretion	4/2112	16/18670	0.09821	0.2458	0.1776	TAC1/PTPN11/AGTR1/REN	4
BP	GO:2001170	negative regulation of ATP biosynthetic process	4/2112	16/18670	0.09821	0.2458	0.1776	PID1/CBFA2T3/HDAC4/PARP1	4
BP	GO:0016485	protein processing	45/2112	328/18670	0.09893	0.2475	0.1789	GAS1/YME1L1/BIRC3/CLU/CST7/GLI3/XPNPEP3/ADAM8/CFP/COMP/CPD/RIPK2/SRGN/PROS1/SPON1/CR1/BAG2/BAK1/GLG1/ASPH/PLAT/AFG3L2/CASP1/CD19/CPE/CYFIP2/IGLC1/IGLV1-44/C7/CPA3/PARP1/IGHG1/ADAM10/SEC11A/METAP2/CFB/CD81/REN/RFX4/GSN/IL1B/CR2/C6/CTSH/PCSK7	45
BP	GO:0032526	response to retinoic acid	17/2112	108/18670	0.09962	0.249	0.1799	EPHA3/WNT5B/SOX9/MICB/YAP1/PCK1/NDUFA13/FZD4/FZD7/RBP4/LEP/CD38/TESC/LYN/IGFBP2/CTSH/BRINP1	17
BP	GO:1904659	glucose transmembrane transport	17/2112	108/18670	0.09962	0.249	0.1799	ENPP1/PID1/PIK3R1/IGF1/PRKCB/SLC2A6/SLC2A3/PTPN11/SLC2A10/LEP/SLC5A3/ADIPOQ/FABP5/SORBS1/CLIP3/SLC2A5/IL1B	17
BP	GO:0036473	cell death in response to oxidative stress	15/2112	93/18670	0.09964	0.249	0.1799	SIGMAR1/OXR1/JAK2/MELK/LANCL1/HGF/SOD1/ARL6IP5/PARP1/HSPB1/PINK1/FOXO3/BAG5/TLR6/PML	15
BP	GO:0006090	pyruvate metabolic process	23/2112	154/18670	0.1003	0.2506	0.1811	IGF1/ZBTB20/SLC2A6/CBFA2T3/NUP93/HDAC4/HK3/ALDOC/PC/MPC2/TPR/PCK1/NUP160/HTR2A/GLO1/IFNG/ARNT/PDK4/MPC1/HAGH/NUP88/NUP50/TP53	23
BP	GO:0043647	inositol phosphate metabolic process	12/2112	71/18670	0.1007	0.2514	0.1817	PLCE1/FGF2/PLCG2/PLEK/INPP1/HRH1/NUDT11/P2RY6/PPIP5K1/INPP5D/PTH1R/MTMR2	12
BP	GO:1902807	negative regulation of cell cycle G1/S phase transition	20/2112	131/18670	0.1008	0.2517	0.1818	CDKN2C/TFDP2/KANK2/BTN2A2/E2F8/FHL1/CDK1/EZH2/PLK2/CCNB1/DACT1/CCND1/RB1/PKD2/PRMT1/PCBP4/TP53/CCL2/AURKA/PML	20
BP	GO:0000303	response to superoxide	6/2112	29/18670	0.102	0.2529	0.1827	GCH1/NQO1/CD36/FBLN5/SOD1/RGN	6
BP	GO:0006929	substrate-dependent cell migration	6/2112	29/18670	0.102	0.2529	0.1827	PTPRC/MYH10/SEMA3A/ITGB1BP1/ADAM8/CTTN	6
BP	GO:0007628	adult walking behavior	6/2112	29/18670	0.102	0.2529	0.1827	UCHL1/ZIC1/GLRB/OXR1/NPC1/HIPK2	6
BP	GO:0010954	positive regulation of protein processing	6/2112	29/18670	0.102	0.2529	0.1827	ADAM8/SPON1/BAG2/GSN/IL1B/C6	6
BP	GO:0021602	cranial nerve morphogenesis	6/2112	29/18670	0.102	0.2529	0.1827	GLI3/SEMA3A/SIX1/EPHB1/SEMA3F/TFAP2A	6
BP	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	6/2112	29/18670	0.102	0.2529	0.1827	CDKN1C/TGFBR3/CREBBP/HSP90AB1/FERMT1/HIPK2	6
BP	GO:0031063	regulation of histone deacetylation	6/2112	29/18670	0.102	0.2529	0.1827	SKI/PRKD2/NIPBL/PINK1/PRKD1/TP53	6
BP	GO:0034367	protein-containing complex remodeling	6/2112	29/18670	0.102	0.2529	0.1827	ABCG1/LIPG/AGTR1/CETP/LIPC/PLA2G7	6
BP	GO:0035666	TRIF-dependent toll-like receptor signaling pathway	6/2112	29/18670	0.102	0.2529	0.1827	TRAF3/BIRC3/IRF7/UBE2D1/IKBKG/TLR6	6
BP	GO:0042226	interleukin-6 biosynthetic process	6/2112	29/18670	0.102	0.2529	0.1827	CD74/CLEC7A/SYK/INPP5D/TLR6/IL1B	6
BP	GO:0044788	modulation by host of viral process	6/2112	29/18670	0.102	0.2529	0.1827	NUCKS1/PC/IFI27/FBXL2/CFL1/PTX3	6
BP	GO:0046134	pyrimidine nucleoside biosynthetic process	6/2112	29/18670	0.102	0.2529	0.1827	TYMP/UPP1/NME7/NME4/TK2/TK1	6
BP	GO:0055075	potassium ion homeostasis	6/2112	29/18670	0.102	0.2529	0.1827	KCNJ2/ATP1B1/ATP1A2/SLC12A2/SLC12A8/SLC12A7	6
BP	GO:0061099	negative regulation of protein tyrosine kinase activity	6/2112	29/18670	0.102	0.2529	0.1827	PTPRC/SH3BP5/PTPN2/GPRC5A/ZGPAT/MVP	6
BP	GO:0070723	response to cholesterol	6/2112	29/18670	0.102	0.2529	0.1827	CCR5/LRP6/INHBA/NFE2L1/PMVK/DAG1	6
BP	GO:1900181	negative regulation of protein localization to nucleus	6/2112	29/18670	0.102	0.2529	0.1827	ANGPT1/CD36/LILRB4/MFHAS1/FERMT1/DCLK1	6
BP	GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus	6/2112	29/18670	0.102	0.2529	0.1827	CDKN1C/TGFBR3/CREBBP/HSP90AB1/FERMT1/HIPK2	6
BP	GO:2000515	negative regulation of CD4-positive, alpha-beta T cell activation	6/2112	29/18670	0.102	0.2529	0.1827	XCL1/RUNX3/IL4R/LGALS9/TWSG1/TBX21	6
BP	GO:0071241	cellular response to inorganic substance	31/2112	217/18670	0.1023	0.2534	0.1831	CPNE3/NQO1/AKR1C3/NFE2L1/EGFR/BLM/CCNA2/NLGN1/SOD1/FOXO1/ATRX/ECT2/TIMELESS/CCNB1/TFAP2A/SYT17/PARP1/SLC25A23/HFE/BACE1/RYR3/GUCA1A/FABP4/CEBPA/FSTL3/PKD2/CFLAR/NCF1/ALAD/GSN/MT1X	31
BP	GO:0034637	cellular carbohydrate biosynthetic process	14/2112	86/18670	0.1028	0.2544	0.1838	ENPP1/IGF1/PPP1R3C/EXTL2/AKR1B1/PASK/PCK1/PER2/LEP/PPP1CA/SORBS1/EXT2/B3GNT2/UGP2	14
BP	GO:0090559	regulation of membrane permeability	14/2112	86/18670	0.1028	0.2544	0.1838	TFDP2/GZMB/BID/RASIP1/EYA2/TMEM14A/BAK1/TP63/PMAIP1/SLC25A5/TP53BP2/TP53/BNIP3L/MOAP1	14
BP	GO:0030032	lamellipodium assembly	11/2112	64/18670	0.1029	0.2544	0.1838	WASF3/RAC2/AUTS2/HDAC4/WAS/ABLIM1/RHOD/FER/WASF2/S1PR1/VAV3	11
BP	GO:0036498	IRE1-mediated unfolded protein response	11/2112	64/18670	0.1029	0.2544	0.1838	ACADVL/EXTL2/SEC31A/BAK1/TSPYL2/EDEM1/KDELR3/GFPT1/FKBP14/LMNA/TATDN2	11
BP	GO:0045600	positive regulation of fat cell differentiation	11/2112	64/18670	0.1029	0.2544	0.1838	SFRP1/WNT5B/LMO3/ZBTB16/AAMDC/ADIRF/LRP5/HTR2A/ZFP36L1/CEBPA/WIF1	11
BP	GO:0045670	regulation of osteoclast differentiation	11/2112	64/18670	0.1029	0.2544	0.1838	PIK3R1/SFRP1/LILRB3/CCR1/LILRB4/CA2/IFNG/INPP5D/FSTL3/TOB2/LILRB1	11
BP	GO:0050830	defense response to Gram-positive bacterium	16/2112	101/18670	0.1032	0.2549	0.1841	IL27RA/GBP2/MYD88/TLR2/CD36/LYZ/TNFRSF14/RIPK2/FGR/HLA-E/KRT6A/IL6/PPP1R11/NOD1/STAB2/NLRP3	16
BP	GO:0090090	negative regulation of canonical Wnt signaling pathway	26/2112	178/18670	0.1038	0.2563	0.1852	PSMB9/SFRP1/PSMB8/LRP6/WNT5B/RBMS3/PSMB10/SOX9/GLI3/IGFBP6/PSME1/TCF7L2/SOX2/CDH2/FOXO1/NOTCH1/DACT1/WWTR1/FZD6/DDIT3/FOXO3/FERMT1/IGFBP2/DVL1/DKK3/NPHP4	26
BP	GO:0048008	platelet-derived growth factor receptor signaling pathway	10/2112	57/18670	0.1048	0.2585	0.1868	PLEKHA1/PTPN2/SGPL1/JAK2/PDGFD/PDGFRL/PLAT/PTPN11/ADIPOQ/FER	10
BP	GO:0072431	signal transduction involved in mitotic G1 DNA damage checkpoint	10/2112	57/18670	0.1048	0.2585	0.1868	TFDP2/E2F8/CDK1/PLK2/CCNB1/PRMT1/PCBP4/TP53/AURKA/PML	10
BP	GO:1902400	intracellular signal transduction involved in G1 DNA damage checkpoint	10/2112	57/18670	0.1048	0.2585	0.1868	TFDP2/E2F8/CDK1/PLK2/CCNB1/PRMT1/PCBP4/TP53/AURKA/PML	10
BP	GO:0009161	ribonucleoside monophosphate metabolic process	48/2112	354/18670	0.1053	0.2594	0.1874	ENPP1/PID1/AMPD3/IGF1/NT5E/ZBTB20/NDUFC1/UPP1/BID/ADK/NDUFS2/SLC2A6/CBFA2T3/COX7A1/NUP93/HDAC4/NDUFS4/HK3/ADA/ALDOC/TPR/CDK1/NDUFA13/NUP160/AK1/HTR2A/ATP1B1/VCP/IFNG/ARNT/CCNB1/ATP1A2/MECP2/NUDT11/PARP1/SLC25A23/PINK1/NDUFA9/NUP88/SDHA/NDUFB6/NUP50/TP53/ATP6V1B2/CASK/NDUFA4/PRPS2/COX7A2	48
BP	GO:0010573	vascular endothelial growth factor production	7/2112	36/18670	0.1054	0.2594	0.1874	CCR2/SULF1/IL6ST/ARNT/IL6/NDRG2/IL1B	7
BP	GO:0045740	positive regulation of DNA replication	7/2112	36/18670	0.1054	0.2594	0.1874	EGFR/E2F8/CDK1/ATRX/TNFAIP1/CDC7/DBF4	7
BP	GO:0050931	pigment cell differentiation	7/2112	36/18670	0.1054	0.2594	0.1874	ENPP1/KITLG/MREG/GLI3/RAB27A/OR51E2/EDNRB	7
BP	GO:0051973	positive regulation of telomerase activity	7/2112	36/18670	0.1054	0.2594	0.1874	PRKCQ/NEK7/NEK2/HSP90AB1/AURKB/PARM1/PARN	7
BP	GO:0003151	outflow tract morphogenesis	13/2112	79/18670	0.106	0.2605	0.1882	BMP4/NPY1R/FOXC1/ZFPM2/SIX1/BMPR1A/DHRS3/TGFBR3/PARVA/NOTCH1/HEY2/NIPBL/FZD2	13
BP	GO:1902806	regulation of cell cycle G1/S phase transition	29/2112	202/18670	0.106	0.2605	0.1882	CDKN2C/TFDP2/CCND2/BID/KANK2/PSME1/EGFR/BTN2A2/CDC45/PTPN6/E2F8/FHL1/CDK1/EZH2/HYAL1/PLK2/CCNB1/DACT1/CCND1/PAF1/RB1/CUL4B/PKD2/PRMT1/PCBP4/TP53/CCL2/AURKA/PML	29
BP	GO:0009409	response to cold	9/2112	50/18670	0.1061	0.2605	0.1882	ACADVL/NFE2L1/PLAC8/CXCL10/NFKBIA/FOXO1/TMEM135/UCP2/THRA	9
BP	GO:0060425	lung morphogenesis	9/2112	50/18670	0.1061	0.2605	0.1882	BMP4/DLG5/SOX9/FGF7/YAP1/DAG1/NFIB/HOXA5/CTSH	9
BP	GO:0060976	coronary vasculature development	9/2112	50/18670	0.1061	0.2605	0.1882	BMP4/MYH10/TGFBR3/SGCD/NOTCH1/HEY2/APLNR/MEGF8/VEGFB	9
BP	GO:0072698	protein localization to microtubule cytoskeleton	9/2112	50/18670	0.1061	0.2605	0.1882	MAPRE2/MCPH1/TTK/SNX10/DVL1/KIF20B/GOLGB1/AURKA/STIL	9
BP	GO:0030866	cortical actin cytoskeleton organization	8/2112	43/18670	0.1065	0.2609	0.1885	EPB41L2/WASL/WAS/PLEK/NCKAP1L/RACGAP1/ECT2/KIF23	8
BP	GO:0032459	regulation of protein oligomerization	8/2112	43/18670	0.1065	0.2609	0.1885	AIM2/CLU/MMP1/BID/CRYAB/PMAIP1/CRBN/TP53	8
BP	GO:0032924	activin receptor signaling pathway	8/2112	43/18670	0.1065	0.2609	0.1885	SKI/INHBA/MAGI2/SMAD3/ACVR1/FGF9/FST/FSTL3	8
BP	GO:0043616	keratinocyte proliferation	8/2112	43/18670	0.1065	0.2609	0.1885	BCL11B/FGF7/YAP1/TP63/ZFP36L1/FERMT1/PRKD1/CASK	8
BP	GO:0070296	sarcoplasmic reticulum calcium ion transport	8/2112	43/18670	0.1065	0.2609	0.1885	CCR5/SRI/ANK2/PLN/ATP1A2/SLC8A1/GSTO1/GSTM2	8
BP	GO:1901216	positive regulation of neuron death	15/2112	94/18670	0.1068	0.2616	0.189	CLU/NQO1/ITGB2/MAP3K11/HDAC4/IFNG/KMO/TFAP2A/PARP1/BACE1/DDIT3/FOXO3/TP53BP2/TP53/TLR6	15
BP	GO:0072175	epithelial tube formation	20/2112	132/18670	0.1068	0.2616	0.189	SFRP1/BMP4/LRP6/SOX9/SKI/SIX1/COBL/DLC1/SPINT2/TCTN1/VASP/TULP3/APAF1/FZD6/CFL1/DVL1/KIF20B/FZD2/PFN1/STIL	20
BP	GO:0050807	regulation of synapse organization	31/2112	218/18670	0.1069	0.2617	0.1891	SEMA4A/DLG5/LILRB2/SEMA4D/NTRK2/TLR2/PTPRD/SIX1/ITSN1/DAG1/ETV5/ARHGAP22/NLGN1/CLSTN1/EPHB1/PTN/PDLIM5/CDH2/PTPRS/SEMA3F/EFNA5/VCP/IL10RA/GPC4/CHMP2B/CFL1/LRRN3/ADAM10/CDC20/ABI2/ACTR2	31
BP	GO:0010951	negative regulation of endopeptidase activity	35/2112	250/18670	0.1078	0.2637	0.1906	LAMP3/SERPINA1/TNFAIP8/BIRC3/TIMP3/SPOCK2/CST7/SERPINA3/SERPINA5/SLPI/PTTG1/SPOCK1/TIMP4/CRYAB/TIMP2/RPS6KA1/RECK/PROS1/CR1/UBE2Z/SPINT2/ITIH5/HGF/CD27/PEBP1/LEF1/SERPINI1/MICAL1/LXN/SERPINB1/APLP2/TFPI/NLE1/CFLAR/SPINK5	35
BP	GO:0010906	regulation of glucose metabolic process	18/2112	117/18670	0.1088	0.266	0.1922	ENPP1/IGF1/NFE2L1/PTPN2/PASK/SIK1/COX11/ACACB/FAM3C/PMAIP1/FOXO1/LEP/PPP1CA/RGN/ADIPOQ/PDK4/SORBS1/TP53	18
BP	GO:0031398	positive regulation of protein ubiquitination	18/2112	117/18670	0.1088	0.266	0.1922	BIRC3/ANGPT1/UBE2C/NOD2/MALT1/GOLGA2/PLK1/NMI/RIPK2/CDC14B/FANCI/CHFR/SPHK1/UBE2D1/PINK1/PTPN22/CDC20/NDFIP1	18
BP	GO:1901222	regulation of NIK/NF-kappaB signaling	18/2112	117/18670	0.1088	0.266	0.1922	CCL19/TLR2/LGALS9/NOD2/MALT1/EGFR/TSPAN6/SPHK1/CD27/NFKBIA/TRIP6/PTPN22/IL18/AKIP1/NOD1/TLR6/IL1B/NLRP3	18
BP	GO:0038034	signal transduction in absence of ligand	12/2112	72/18670	0.1091	0.2662	0.1923	KITLG/EYA4/BCL2A1/INHBA/EYA2/BAK1/BCL2L2/PPP1CA/FOXO3/ITGAV/MOAP1/IL1B	12
BP	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand	12/2112	72/18670	0.1091	0.2662	0.1923	KITLG/EYA4/BCL2A1/INHBA/EYA2/BAK1/BCL2L2/PPP1CA/FOXO3/ITGAV/MOAP1/IL1B	12
BP	GO:1903556	negative regulation of tumor necrosis factor superfamily cytokine production	12/2112	72/18670	0.1091	0.2662	0.1923	TNFAIP3/IL27RA/IGF1/SLAMF1/AXL/LGALS9/PTPN6/GPR18/CLEC4A/ADIPOQ/PTPN22/LILRB1	12
BP	GO:0008643	carbohydrate transport	22/2112	148/18670	0.1102	0.268	0.1936	ENPP1/PID1/PIK3R1/IGF1/SLC17A5/PRKCB/SLC2A6/AQP9/SLC37A1/SLC2A3/PTPN11/SLC2A10/LEP/SLC5A3/ADIPOQ/FABP5/SORBS1/CLIP3/SLC23A2/SLC35A2/SLC2A5/IL1B	22
BP	GO:0002347	response to tumor cell	5/2112	23/18670	0.1104	0.268	0.1936	PRF1/RBMS3/CRTAM/CD160/CD226	5
BP	GO:0019400	alditol metabolic process	5/2112	23/18670	0.1104	0.268	0.1936	GK/DYSF/AKR1B1/PCK1/LEP	5
BP	GO:0032373	positive regulation of sterol transport	5/2112	23/18670	0.1104	0.268	0.1936	ABCG1/NFKBIA/LIPG/ADIPOQ/NR1H3	5
BP	GO:0032376	positive regulation of cholesterol transport	5/2112	23/18670	0.1104	0.268	0.1936	ABCG1/NFKBIA/LIPG/ADIPOQ/NR1H3	5
BP	GO:0032703	negative regulation of interleukin-2 production	5/2112	23/18670	0.1104	0.268	0.1936	XCL1/PTPRC/TNFAIP3/GBP1/TBX21	5
BP	GO:0042451	purine nucleoside biosynthetic process	5/2112	23/18670	0.1104	0.268	0.1936	NT5E/ADK/NME7/ADA/NME4	5
BP	GO:0045821	positive regulation of glycolytic process	5/2112	23/18670	0.1104	0.268	0.1936	IGF1/ZBTB20/HTR2A/IFNG/ARNT	5
BP	GO:0046129	purine ribonucleoside biosynthetic process	5/2112	23/18670	0.1104	0.268	0.1936	NT5E/ADK/NME7/ADA/NME4	5
BP	GO:0060055	angiogenesis involved in wound healing	5/2112	23/18670	0.1104	0.268	0.1936	NDNF/TNFAIP3/CXCR4/DAG1/GPR4	5
BP	GO:0060445	branching involved in salivary gland morphogenesis	5/2112	23/18670	0.1104	0.268	0.1936	SEMA3A/FGF7/DAG1/HGF/TGM2	5
BP	GO:0060479	lung cell differentiation	5/2112	23/18670	0.1104	0.268	0.1936	SOX9/YAP1/NFIB/HOXA5/THRA	5
BP	GO:0070193	synaptonemal complex organization	5/2112	23/18670	0.1104	0.268	0.1936	PLK1/UBE2B/STAG3/REC8/TRIP13	5
BP	GO:0090140	regulation of mitochondrial fission	5/2112	23/18670	0.1104	0.268	0.1936	DCN/TMEM135/PINK1/KDR/INF2	5
BP	GO:0099177	regulation of trans-synaptic signaling	58/2112	437/18670	0.1105	0.268	0.1936	CCR2/LILRB2/NTRK2/PREPL/RAB8A/MCTP1/PPP3CA/PRKCB/PFN2/USP46/LAMA2/JAK2/SNCAIP/DNM1/TUBB2B/EGFR/SLC1A3/TAC1/AKAP12/NLGN1/CX3CR1/CLSTN1/EPHB1/PCDH17/PTN/PLAT/CDH2/PTPRS/HTR2A/CHRNA5/HRH1/CA2/PLK2/KMO/ATP1A2/MECP2/FGF14/ADIPOQ/STX4/FABP5/VAMP2/STXBP1/PINK1/BACE1/MAP1B/LGI1/CD38/SYBU/SNCG/CDC20/ABHD6/CYP46A1/DVL1/MTMR2/CCL2/CASK/IL1B/P2RY4	58
BP	GO:0001892	embryonic placenta development	14/2112	87/18670	0.1105	0.268	0.1936	CDKN1C/GATA2/EGFR/E2F8/BPTF/SPINT2/LEF1/ZFP36L1/ARNT/HEY2/KRT19/CEBPA/HEY1/PKD2	14
BP	GO:0014823	response to activity	11/2112	65/18670	0.1119	0.2713	0.196	CXCR4/OXCT1/CDK1/PCK1/PTN/LEP/ADIPOQ/CYBA/CAT/HADH/ALAD	11
BP	GO:0060675	ureteric bud morphogenesis	11/2112	65/18670	0.1119	0.2713	0.196	BMP4/SOX9/GLI3/SIX1/SIX2/FGF2/PBX1/DCHS1/FAT4/PKD2/HOXA11	11
BP	GO:0009167	purine ribonucleoside monophosphate metabolic process	46/2112	340/18670	0.1136	0.2753	0.1989	ENPP1/PID1/AMPD3/IGF1/NT5E/ZBTB20/NDUFC1/BID/ADK/NDUFS2/SLC2A6/CBFA2T3/COX7A1/NUP93/HDAC4/NDUFS4/HK3/ADA/ALDOC/TPR/CDK1/NDUFA13/NUP160/AK1/HTR2A/ATP1B1/VCP/IFNG/ARNT/CCNB1/ATP1A2/MECP2/NUDT11/PARP1/SLC25A23/PINK1/NDUFA9/NUP88/SDHA/NDUFB6/NUP50/TP53/ATP6V1B2/CASK/NDUFA4/COX7A2	46
BP	GO:0010256	endomembrane system organization	58/2112	438/18670	0.1139	0.2757	0.1992	PTPRC/SYNGR2/ARL1/BIN2/CLU/MICALL1/TMEM43/MYH10/CXCR4/PDE4DIP/PPP2CA/ANK2/PRKCB/CCNB2/GAK/AR/VRK1/DYSF/GOLGA2/PLK1/NUP93/WASL/DNM1/ATP8B2/SRGN/SEC31A/CDK1/VCPIP1/FA2H/RAB33B/HOOK2/STX16/SOD1/RAB27A/VPS37C/TOR1AIP1/CCNB1/STX18/FNBP1L/CAMSAP2/UBL4A/SCARB2/FAT4/CHMP2B/PLSCR1/LMNA/PRKD1/MPP5/SNX10/BAG5/GOLGB1/SH3TC2/STX6/UGCG/TMCC1/SPTBN1/GSN/CHMP1B	58
BP	GO:0097061	dendritic spine organization	13/2112	80/18670	0.1142	0.2763	0.1997	DOCK10/ZNF365/WASL/NLGN1/EPHB1/PDLIM5/CTTN/CFL1/ADAM10/DVL1/ABI2/MTMR2/ACTR2	13
BP	GO:0051196	regulation of coenzyme metabolic process	15/2112	95/18670	0.1143	0.2765	0.1998	IGF1/ZBTB20/SLC2A6/CBFA2T3/NUP93/HDAC4/TPR/NUP160/HTR2A/IFNG/ARNT/PDK4/NUP88/NUP50/TP53	15
BP	GO:0030705	cytoskeleton-dependent intracellular transport	26/2112	180/18670	0.1144	0.2767	0.1999	UCHL1/RASGRP1/DYNC2LI1/MREG/PURA/TRAK2/WASL/KIF3B/HOOK2/KIF4A/DYNC1I1/SOD1/CCDC88C/CLUAP1/FEZ1/FNBP1L/MYO1C/TRIM58/HSPB1/MAP1B/SYBU/DYNLRB1/ARL3/FYCO1/KIF1B/KIF23	26
BP	GO:1903749	positive regulation of establishment of protein localization to mitochondrion	10/2112	58/18670	0.1145	0.2769	0.2001	TFDP2/RAC2/GZMB/BID/TP63/PMAIP1/PINK1/HSPA1L/TP53BP2/TP53	10
BP	GO:0000002	mitochondrial genome maintenance	6/2112	30/18670	0.116	0.2772	0.2003	TYMP/SLC25A36/SLC25A4/PARP1/AKT3/TP53	6
BP	GO:0000305	response to oxygen radical	6/2112	30/18670	0.116	0.2772	0.2003	GCH1/NQO1/CD36/FBLN5/SOD1/RGN	6
BP	GO:0044818	mitotic G2/M transition checkpoint	6/2112	30/18670	0.116	0.2772	0.2003	BLM/CDK1/DONSON/SYF2/NAE1/TOPBP1	6
BP	GO:0045939	negative regulation of steroid metabolic process	6/2112	30/18670	0.116	0.2772	0.2003	ERLIN1/SOD1/NFKB1/ERLIN2/GFI1/DKK3	6
BP	GO:0071480	cellular response to gamma radiation	6/2112	30/18670	0.116	0.2772	0.2003	CRYAB/YAP1/NOX4/CYBA/TP53/GTF2H5	6
BP	GO:1904837	beta-catenin-TCF complex assembly	6/2112	30/18670	0.116	0.2772	0.2003	CREBBP/TCF7/TCF7L2/LEF1/TCF7L1/DACT1	6
BP	GO:0031396	regulation of protein ubiquitination	29/2112	204/18670	0.116	0.2772	0.2003	TNFAIP3/BIRC3/ANGPT1/UBE2C/NOD2/MALT1/DYSF/MAD2L1/GOLGA2/PLK1/NMI/RIPK2/CDC14B/FANCI/CHFR/SPHK1/BAG2/PER2/UBE2D1/HSP90AB1/FBXO5/PINK1/PTPN22/IVNS1ABP/CDC20/NDFIP1/BAG5/CAMLG/ISG15	29
BP	GO:0050773	regulation of dendrite development	22/2112	149/18670	0.1161	0.2772	0.2003	DLG5/SEMA4D/PPP3CA/LPAR1/PTPRD/ITSN1/COBL/NLGN1/EZH2/CAMK1D/PTN/PDLIM5/PTPRS/PLK2/CAMSAP2/MARK1/BCL11A/CFL1/ADAM10/CDC20/ABI2/ACTR2	22
BP	GO:0097366	response to bronchodilator	9/2112	51/18670	0.1166	0.2772	0.2003	CCL19/PPP3CA/CCR7/ICAM1/SLC18A2/CCNA2/SOD1/FOXO1/CFLAR	9
BP	GO:0002418	immune response to tumor cell	4/2112	17/18670	0.1175	0.2772	0.2003	PRF1/CRTAM/CD160/CD226	4
BP	GO:0003184	pulmonary valve morphogenesis	4/2112	17/18670	0.1175	0.2772	0.2003	BMP4/NOTCH1/HEY2/HEY1	4
BP	GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	4/2112	17/18670	0.1175	0.2772	0.2003	TMEM100/NOTCH1/HEY2/ACVR1	4
BP	GO:0006825	copper ion transport	4/2112	17/18670	0.1175	0.2772	0.2003	SCO2/CP/SLC31A2/CUTC	4
BP	GO:0006883	cellular sodium ion homeostasis	4/2112	17/18670	0.1175	0.2772	0.2003	ATP1B1/ATP1A2/C7/SLC8A1	4
BP	GO:0014733	regulation of skeletal muscle adaptation	4/2112	17/18670	0.1175	0.2772	0.2003	IGFBP5/PPP3CA/GTF2IRD2B/GTF2IRD1	4
BP	GO:0018904	ether metabolic process	4/2112	17/18670	0.1175	0.2772	0.2003	EPHX1/EPHX3/EPHX2/TXN2	4
BP	GO:0033262	regulation of nuclear cell cycle DNA replication	4/2112	17/18670	0.1175	0.2772	0.2003	ATRX/CDC7/TERF1/DBF4	4
BP	GO:0034433	steroid esterification	4/2112	17/18670	0.1175	0.2772	0.2003	ABCG1/ACAT1/AGTR1/SOAT2	4
BP	GO:0034434	sterol esterification	4/2112	17/18670	0.1175	0.2772	0.2003	ABCG1/ACAT1/AGTR1/SOAT2	4
BP	GO:0034435	cholesterol esterification	4/2112	17/18670	0.1175	0.2772	0.2003	ABCG1/ACAT1/AGTR1/SOAT2	4
BP	GO:0034501	protein localization to kinetochore	4/2112	17/18670	0.1175	0.2772	0.2003	NDC80/CDK1/TTK/AURKB	4
BP	GO:0035930	corticosteroid hormone secretion	4/2112	17/18670	0.1175	0.2772	0.2003	TAC1/PTPN11/AGTR1/REN	4
BP	GO:0036149	phosphatidylinositol acyl-chain remodeling	4/2112	17/18670	0.1175	0.2772	0.2003	PLA2G2D/PLA2G12A/PLA2G4C/MBOAT7	4
BP	GO:0042994	cytoplasmic sequestering of transcription factor	4/2112	17/18670	0.1175	0.2772	0.2003	SRI/NFKBIE/NFKBIA/PKD2	4
BP	GO:0043373	CD4-positive, alpha-beta T cell lineage commitment	4/2112	17/18670	0.1175	0.2772	0.2003	BATF/IRF4/TBX21/IL6	4
BP	GO:0045072	regulation of interferon-gamma biosynthetic process	4/2112	17/18670	0.1175	0.2772	0.2003	TLR8/INHBA/CLEC7A/LILRB1	4
BP	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate	4/2112	17/18670	0.1175	0.2772	0.2003	APOBEC3G/CXCL8/TOP2A/MPHOSPH8	4
BP	GO:0046500	S-adenosylmethionine metabolic process	4/2112	17/18670	0.1175	0.2772	0.2003	BHMT2/AHCYL1/MAT1A/AHCYL2	4
BP	GO:0048532	anatomical structure arrangement	4/2112	17/18670	0.1175	0.2772	0.2003	SEMA3A/BMPR1A/SEMA3F/TFAP2A	4
BP	GO:0051284	positive regulation of sequestering of calcium ion	4/2112	17/18670	0.1175	0.2772	0.2003	SRI/PKD2/GSTO1/GSTM2	4
BP	GO:0055070	copper ion homeostasis	4/2112	17/18670	0.1175	0.2772	0.2003	SCO2/SLC31A2/CUTC/PRND	4
BP	GO:0060263	regulation of respiratory burst	4/2112	17/18670	0.1175	0.2772	0.2003	SLAMF8/RAC2/CLEC7A/CAMK1D	4
BP	GO:0061952	midbody abscission	4/2112	17/18670	0.1175	0.2772	0.2003	CEP55/KIF20A/CHMP2B/CHMP1B	4
BP	GO:0071850	mitotic cell cycle arrest	4/2112	17/18670	0.1175	0.2772	0.2003	CDC14B/MAGI2/MCPH1/TP53	4
BP	GO:1903975	regulation of glial cell migration	4/2112	17/18670	0.1175	0.2772	0.2003	CCR2/GPR183/IDH2/CX3CR1	4
BP	GO:1904355	positive regulation of telomere capping	4/2112	17/18670	0.1175	0.2772	0.2003	PRKCQ/NEK7/NEK2/AURKB	4
BP	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell	4/2112	17/18670	0.1175	0.2772	0.2003	CCR2/ITGA4/ITGB2/ICAM1	4
BP	GO:0009126	purine nucleoside monophosphate metabolic process	46/2112	341/18670	0.1176	0.2772	0.2003	ENPP1/PID1/AMPD3/IGF1/NT5E/ZBTB20/NDUFC1/BID/ADK/NDUFS2/SLC2A6/CBFA2T3/COX7A1/NUP93/HDAC4/NDUFS4/HK3/ADA/ALDOC/TPR/CDK1/NDUFA13/NUP160/AK1/HTR2A/ATP1B1/VCP/IFNG/ARNT/CCNB1/ATP1A2/MECP2/NUDT11/PARP1/SLC25A23/PINK1/NDUFA9/NUP88/SDHA/NDUFB6/NUP50/TP53/ATP6V1B2/CASK/NDUFA4/COX7A2	46
BP	GO:0046128	purine ribonucleoside metabolic process	12/2112	73/18670	0.1178	0.2772	0.2003	AMPD3/NT5E/ADK/NME7/ADA/AHCYL1/MOCS2/PNP/MBIP/AHCYL2/NME4/CASK	12
BP	GO:0006195	purine nucleotide catabolic process	8/2112	44/18670	0.1179	0.2772	0.2003	AMPD3/NT5E/ADA/PDE1A/ACAT1/NUDT11/PNP/HINT1	8
BP	GO:0046688	response to copper ion	8/2112	44/18670	0.1179	0.2772	0.2003	NFE2L1/PAM/ICAM1/CDK1/S100A13/SOD1/BACE1/MT1X	8
BP	GO:0051489	regulation of filopodium assembly	8/2112	44/18670	0.1179	0.2772	0.2003	CCR7/WASL/CCL21/NLGN1/PPP1R16B/FNBP1L/DPYSL3/TGFB3	8
BP	GO:0060412	ventricular septum morphogenesis	8/2112	44/18670	0.1179	0.2772	0.2003	BMP4/ZFPM2/TGFBR3/NOTCH1/HEY2/ACVR1/HEY1/FZD2	8
BP	GO:0090311	regulation of protein deacetylation	8/2112	44/18670	0.1179	0.2772	0.2003	SKI/PRKD2/IFNG/BEX4/NIPBL/PINK1/PRKD1/TP53	8
BP	GO:0003156	regulation of animal organ formation	7/2112	37/18670	0.118	0.2772	0.2003	BMP4/PIM1/AR/SULF1/SIX1/NOTCH1/HOXA11	7
BP	GO:0010614	negative regulation of cardiac muscle hypertrophy	7/2112	37/18670	0.118	0.2772	0.2003	TNFRSF1B/FOXO1/SMAD3/NOTCH1/PAK1/JARID2/LMNA	7
BP	GO:0031111	negative regulation of microtubule polymerization or depolymerization	7/2112	37/18670	0.118	0.2772	0.2003	CKAP2/FGF13/TUBB4A/CAMSAP2/MAP1B/CLIP3/CDH5	7
BP	GO:0043029	T cell homeostasis	7/2112	37/18670	0.118	0.2772	0.2003	CORO1A/CCNB2/TCIRG1/LGALS9/NCKAP1L/PMAIP1/IL2RA	7
BP	GO:0051084	'de novo' posttranslational protein folding	7/2112	37/18670	0.118	0.2772	0.2003	CD74/GAK/HSPA6/DNAJC7/HSPA1L/DNAJB4/ST13	7
BP	GO:1905314	semi-lunar valve development	7/2112	37/18670	0.118	0.2772	0.2003	BMP4/TNFRSF1B/SOX9/NOTCH1/HEY2/RB1/HEY1	7
BP	GO:2000273	positive regulation of signaling receptor activity	7/2112	37/18670	0.118	0.2772	0.2003	CCR2/IFNG/HFE/PINK1/RWDD1/NCF1/CCL2	7
BP	GO:1902476	chloride transmembrane transport	14/2112	88/18670	0.1184	0.2772	0.2003	APOL1/PCYOX1/GLRB/FXYD1/SLC26A2/CLCN4/SLC1A3/SLC12A2/SLC12A8/CLIC5/SLC12A7/CLCN7/CLCN5/CLCC1	14
BP	GO:0001821	histamine secretion	3/2112	11/18670	0.1194	0.2772	0.2003	ADA/BTK/LYN	3
BP	GO:0002730	regulation of dendritic cell cytokine production	3/2112	11/18670	0.1194	0.2772	0.2003	NOD2/DDX58/DDX1	3
BP	GO:0002836	positive regulation of response to tumor cell	3/2112	11/18670	0.1194	0.2772	0.2003	CRTAM/CD160/CD226	3
BP	GO:0002839	positive regulation of immune response to tumor cell	3/2112	11/18670	0.1194	0.2772	0.2003	CRTAM/CD160/CD226	3
BP	GO:0002887	negative regulation of myeloid leukocyte mediated immunity	3/2112	11/18670	0.1194	0.2772	0.2003	CCR2/LGALS9/IL13RA2	3
BP	GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	3/2112	11/18670	0.1194	0.2772	0.2003	PTPRC/PTPN6/CR1	3
BP	GO:0003093	regulation of glomerular filtration	3/2112	11/18670	0.1194	0.2772	0.2003	EMP2/CORO2B/CYBA	3
BP	GO:0003264	regulation of cardioblast proliferation	3/2112	11/18670	0.1194	0.2772	0.2003	PIM1/SIX1/NOTCH1	3
BP	GO:0006048	UDP-N-acetylglucosamine biosynthetic process	3/2112	11/18670	0.1194	0.2772	0.2003	NAGK/GFPT1/GFPT2	3
BP	GO:0006558	L-phenylalanine metabolic process	3/2112	11/18670	0.1194	0.2772	0.2003	FAH/PCBD1/HPD	3
BP	GO:0006559	L-phenylalanine catabolic process	3/2112	11/18670	0.1194	0.2772	0.2003	FAH/PCBD1/HPD	3
BP	GO:0009125	nucleoside monophosphate catabolic process	3/2112	11/18670	0.1194	0.2772	0.2003	AMPD3/NT5E/NUDT11	3
BP	GO:0010172	embryonic body morphogenesis	3/2112	11/18670	0.1194	0.2772	0.2003	MAB21L2/CDON/DAG1	3
BP	GO:0014820	tonic smooth muscle contraction	3/2112	11/18670	0.1194	0.2772	0.2003	HTR2A/CD38/MYLK	3
BP	GO:0014870	response to muscle inactivity	3/2112	11/18670	0.1194	0.2772	0.2003	SGCA/HDAC4/DAG1	3
BP	GO:0019371	cyclooxygenase pathway	3/2112	11/18670	0.1194	0.2772	0.2003	AKR1C3/HPGDS/PTGS1	3
BP	GO:0021561	facial nerve development	3/2112	11/18670	0.1194	0.2772	0.2003	SEMA3A/SIX1/SEMA3F	3
BP	GO:0021610	facial nerve morphogenesis	3/2112	11/18670	0.1194	0.2772	0.2003	SEMA3A/SIX1/SEMA3F	3
BP	GO:0021670	lateral ventricle development	3/2112	11/18670	0.1194	0.2772	0.2003	MYH10/TSKU/PAX5	3
BP	GO:0031442	positive regulation of mRNA 3'-end processing	3/2112	11/18670	0.1194	0.2772	0.2003	CPEB1/CCNB1/PAF1	3
BP	GO:0032490	detection of molecule of bacterial origin	3/2112	11/18670	0.1194	0.2772	0.2003	TLR2/NOD2/TLR6	3
BP	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase	3/2112	11/18670	0.1194	0.2772	0.2003	ACADVL/ETFB/ACADL	3
BP	GO:0033860	regulation of NAD(P)H oxidase activity	3/2112	11/18670	0.1194	0.2772	0.2003	SLAMF8/AGTR1/CYBA	3
BP	GO:0035766	cell chemotaxis to fibroblast growth factor	3/2112	11/18670	0.1194	0.2772	0.2003	CXCL13/FGF18/FGF2	3
BP	GO:0036444	calcium import into the mitochondrion	3/2112	11/18670	0.1194	0.2772	0.2003	AFG3L2/MICU1/SLC25A23	3
BP	GO:0045351	type I interferon biosynthetic process	3/2112	11/18670	0.1194	0.2772	0.2003	TLR8/IRF7/NMI	3
BP	GO:0045835	negative regulation of meiotic nuclear division	3/2112	11/18670	0.1194	0.2772	0.2003	FBXO5/TTK/TRIP13	3
BP	GO:0046185	aldehyde catabolic process	3/2112	11/18670	0.1194	0.2772	0.2003	ESD/ADH5/HAGH	3
BP	GO:0046501	protoporphyrinogen IX metabolic process	3/2112	11/18670	0.1194	0.2772	0.2003	ALAS1/HMBS/ALAD	3
BP	GO:0046886	positive regulation of hormone biosynthetic process	3/2112	11/18670	0.1194	0.2772	0.2003	IFNG/ARNT/IL1B	3
BP	GO:0051561	positive regulation of mitochondrial calcium ion concentration	3/2112	11/18670	0.1194	0.2772	0.2003	MICU1/SLC25A23/TGM2	3
BP	GO:0051574	positive regulation of histone H3-K9 methylation	3/2112	11/18670	0.1194	0.2772	0.2003	MECP2/JARID2/LMNA	3
BP	GO:0060439	trachea morphogenesis	3/2112	11/18670	0.1194	0.2772	0.2003	BMP4/LRP6/HOXA5	3
BP	GO:0060525	prostate glandular acinus development	3/2112	11/18670	0.1194	0.2772	0.2003	SFRP1/TP63/NOTCH1	3
BP	GO:0070189	kynurenine metabolic process	3/2112	11/18670	0.1194	0.2772	0.2003	IDO1/KYNU/KMO	3
BP	GO:0070213	protein auto-ADP-ribosylation	3/2112	11/18670	0.1194	0.2772	0.2003	PARP12/PARP1/PARP8	3
BP	GO:0070673	response to interleukin-18	3/2112	11/18670	0.1194	0.2772	0.2003	RIPK2/IL18/ALOX5	3
BP	GO:0071372	cellular response to follicle-stimulating hormone stimulus	3/2112	11/18670	0.1194	0.2772	0.2003	INHBA/EFNA5/NOTCH1	3
BP	GO:0072110	glomerular mesangial cell proliferation	3/2112	11/18670	0.1194	0.2772	0.2003	BMP4/PDGFD/CFLAR	3
BP	GO:0072310	glomerular epithelial cell development	3/2112	11/18670	0.1194	0.2772	0.2003	BMP4/MAGI2/ADIPOQ	3
BP	GO:0072321	chaperone-mediated protein transport	3/2112	11/18670	0.1194	0.2772	0.2003	CLU/PEX19/CLIP3	3
BP	GO:0072537	fibroblast activation	3/2112	11/18670	0.1194	0.2772	0.2003	RPS6KA1/AKAP12/LEP	3
BP	GO:0072608	interleukin-10 secretion	3/2112	11/18670	0.1194	0.2772	0.2003	LGALS9/ISG15/LILRB1	3
BP	GO:0072711	cellular response to hydroxyurea	3/2112	11/18670	0.1194	0.2772	0.2003	BLM/ATRX/TIMELESS	3
BP	GO:0090193	positive regulation of glomerulus development	3/2112	11/18670	0.1194	0.2772	0.2003	PDGFD/ADIPOQ/CFLAR	3
BP	GO:1900112	regulation of histone H3-K9 trimethylation	3/2112	11/18670	0.1194	0.2772	0.2003	ATRX/MECP2/LMNA	3
BP	GO:1901569	fatty acid derivative catabolic process	3/2112	11/18670	0.1194	0.2772	0.2003	OXCT1/ACAT1/BDH1	3
BP	GO:1902221	erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process	3/2112	11/18670	0.1194	0.2772	0.2003	FAH/PCBD1/HPD	3
BP	GO:1902222	erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process	3/2112	11/18670	0.1194	0.2772	0.2003	FAH/PCBD1/HPD	3
BP	GO:1904847	regulation of cell chemotaxis to fibroblast growth factor	3/2112	11/18670	0.1194	0.2772	0.2003	CXCL13/FGF18/FGF2	3
BP	GO:1905214	regulation of RNA binding	3/2112	11/18670	0.1194	0.2772	0.2003	NUCKS1/EIF3E/LARP6	3
BP	GO:1905941	positive regulation of gonad development	3/2112	11/18670	0.1194	0.2772	0.2003	SOX9/SEMA3A/ZFPM2	3
BP	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	3/2112	11/18670	0.1194	0.2772	0.2003	DDIT3/MBTPS2/TP53	3
BP	GO:2000318	positive regulation of T-helper 17 type immune response	3/2112	11/18670	0.1194	0.2772	0.2003	PRKCQ/MALT1/NLRP3	3
BP	GO:2000392	regulation of lamellipodium morphogenesis	3/2112	11/18670	0.1194	0.2772	0.2003	ARPIN/PDPN/KANK1	3
BP	GO:0022037	metencephalon development	17/2112	111/18670	0.1202	0.2788	0.2014	CD3E/LRP6/MYH10/FOXC1/LPAR1/ZNF365/EZH2/PTN/PTPRS/FZD4/PTPN11/MECP2/PAK1/SDF4/CLP1/TP53/B4GALT2	17
BP	GO:1903509	liposaccharide metabolic process	17/2112	111/18670	0.1202	0.2788	0.2014	PIGK/STS/B3GALNT1/DPM3/GPAA1/GAL3ST4/FA2H/PIGH/FUCA1/PIGP/AOAH/GLA/PIGT/PIGF/UGCG/CERK/ALDH5A1	17
BP	GO:0015800	acidic amino acid transport	11/2112	66/18670	0.1214	0.2808	0.2029	NTRK2/SLC1A3/SLC25A22/PER2/ARL6IP5/KMO/ATP1A2/PRAF2/VAMP2/STXBP1/LRRC8D	11
BP	GO:0046888	negative regulation of hormone secretion	11/2112	66/18670	0.1214	0.2808	0.2029	SFRP1/INHBA/PPP3CA/KLF7/NMB/PTPN11/LEP/ADIPOQ/HADH/IL1B/RAB11FIP1	11
BP	GO:0051926	negative regulation of calcium ion transport	11/2112	66/18670	0.1214	0.2808	0.2029	LILRB2/SRI/ICAM1/DYSF/GEM/PLN/ATP1A2/PKD2/GSTO1/GSTM2/LILRB1	11
BP	GO:0072171	mesonephric tubule morphogenesis	11/2112	66/18670	0.1214	0.2808	0.2029	BMP4/SOX9/GLI3/SIX1/SIX2/FGF2/PBX1/DCHS1/FAT4/PKD2/HOXA11	11
BP	GO:1901880	negative regulation of protein depolymerization	11/2112	66/18670	0.1214	0.2808	0.2029	ADD3/TMOD1/CKAP2/FGF13/LMOD1/CAMSAP2/MAP1B/CAPZA1/VILL/SPTBN1/GSN	11
BP	GO:0009108	coenzyme biosynthetic process	36/2112	261/18670	0.1214	0.2808	0.2029	IGF1/GCH1/IDO1/ZBTB20/KYNU/SLC2A6/CBFA2T3/PCBD1/NUP93/HDAC4/HK3/ALDOC/MPC2/IDH2/TPR/ACAT1/NUP160/ACACB/HTR2A/MOCS2/HSD17B12/MAT1A/IFNG/ARNT/KMO/RGN/PDK4/NDUFA9/ELOVL4/MPC1/NUP88/ELOVL2/NUP50/TP53/ACSL5/ELOVL5	36
BP	GO:1904062	regulation of cation transmembrane transport	46/2112	342/18670	0.1216	0.2813	0.2032	CXCL9/XCL1/CCR2/CORO1A/SRI/CACNA2D1/ANK2/TCIRG1/FXYD1/DYSF/FXYD6/NETO2/ANXA3/GEM/CXCL10/PTPN6/SLC31A2/FHL1/PLCG2/NLGN1/PLN/KCNJ2/TRPC1/CD19/ATP1B1/SCN1B/IFNG/RGN/ATP1A2/CXCL11/SLC8A1/FGF14/P2RY6/APLNR/VAMP2/PINK1/TESC/CYBA/LYN/PKD2/GSTO1/KCNAB1/GSTM2/CCL2/SNTA1/GPD1L	46
BP	GO:0008585	female gonad development	15/2112	96/18670	0.122	0.2822	0.2039	KITLG/PLEKHA1/SFRP1/FOXC1/INHBA/ZFPM2/SGPL1/ICAM1/SOD1/FZD4/LEP/FOXO3/ANG/NRIP1/PTX3	15
BP	GO:0035567	non-canonical Wnt signaling pathway	22/2112	150/18670	0.1223	0.2827	0.2042	PSMB9/SFRP1/PSMB8/PSMB10/PPP3CA/PSME1/MAGI2/TCF7L2/RYK/PLEKHA4/FZD4/LEF1/FZD7/DAAM2/MYOC/DACT1/GPC4/FZD6/NLK/DVL1/FZD2/PFN1	22
BP	GO:0051193	regulation of cofactor metabolic process	18/2112	119/18670	0.1225	0.2831	0.2045	IGF1/RAC2/ZBTB20/SLC2A6/CBFA2T3/NUP93/HDAC4/TPR/NUP160/HTR2A/IFNG/ARNT/PDK4/PINK1/HP/NUP88/NUP50/TP53	18
BP	GO:0110110	positive regulation of animal organ morphogenesis	13/2112	81/18670	0.1227	0.2833	0.2047	TNFAIP3/BMP4/SOX9/PIM1/FGF7/AR/SIX1/PTN/NOTCH1/TFAP2A/ACVR1/CFLAR/HOXA11	13
BP	GO:0043388	positive regulation of DNA binding	10/2112	59/18670	0.1247	0.2876	0.2078	IGF1/FOXC1/SKI/IRF4/JAK2/IFNG/PARP1/NIPBL/RB1/HIPK2	10
BP	GO:0072413	signal transduction involved in mitotic cell cycle checkpoint	10/2112	59/18670	0.1247	0.2876	0.2078	TFDP2/E2F8/CDK1/PLK2/CCNB1/PRMT1/PCBP4/TP53/AURKA/PML	10
BP	GO:1902402	signal transduction involved in mitotic DNA damage checkpoint	10/2112	59/18670	0.1247	0.2876	0.2078	TFDP2/E2F8/CDK1/PLK2/CCNB1/PRMT1/PCBP4/TP53/AURKA/PML	10
BP	GO:1902403	signal transduction involved in mitotic DNA integrity checkpoint	10/2112	59/18670	0.1247	0.2876	0.2078	TFDP2/E2F8/CDK1/PLK2/CCNB1/PRMT1/PCBP4/TP53/AURKA/PML	10
BP	GO:0019233	sensory perception of pain	16/2112	104/18670	0.1251	0.2883	0.2083	CCR2/UCHL1/PENK/CXCR4/NDN/NPY1R/TAC1/TMEM100/EPHB1/HTR2A/MECP2/LXN/FABP5/EDNRB/BACE1/CCL2	16
BP	GO:0071331	cellular response to hexose stimulus	20/2112	135/18670	0.1261	0.2907	0.21	ZBTB20/SRI/OXCT1/PPP3CA/ICAM1/KLF7/MPC2/PCK1/LRP5/NOX4/EFNA5/PIK3CA/STX4/SYBU/FOXO3/CYBA/RAB11FIP2/SLC2A5/ZNF236/GPR27	20
BP	GO:0009205	purine ribonucleoside triphosphate metabolic process	45/2112	335/18670	0.1264	0.2911	0.2103	ENPP1/PID1/AMPD3/IGF1/ZBTB20/NDUFC1/BID/NDUFS2/SLC2A6/CBFA2T3/COX7A1/NUP93/HDAC4/NDUFS4/HK3/NME7/ALDOC/TPR/CDK1/NDUFA13/NUP160/AK1/HTR2A/ATP1B1/MOCS2/VCP/IFNG/ARNT/CCNB1/ATP1A2/MECP2/MBIP/PARP1/SLC25A23/PINK1/NDUFA9/NME4/NUP88/SDHA/NDUFB6/NUP50/TP53/ATP6V1B2/NDUFA4/COX7A2	45
BP	GO:0032602	chemokine production	14/2112	89/18670	0.1267	0.2913	0.2105	S100A9/TLR2/CD74/IL4R/LGALS9/RIPK2/CLEC7A/IFNG/ADIPOQ/SYK/IL6/CXCL6/IL18/IL1B	14
BP	GO:0072078	nephron tubule morphogenesis	12/2112	74/18670	0.1269	0.2913	0.2105	BMP4/SOX9/GLI3/SIX1/SIX2/FGF2/PBX1/DCHS1/FAT4/PKD2/HOXA11/AHI1	12
BP	GO:0009110	vitamin biosynthetic process	5/2112	24/18670	0.1272	0.2913	0.2105	NFKB1/IFNG/RGN/GFI1/IL1B	5
BP	GO:0042104	positive regulation of activated T cell proliferation	5/2112	24/18670	0.1272	0.2913	0.2105	IGF1/ICOSLG/IL18/IGFBP2/IL2RA	5
BP	GO:0046426	negative regulation of JAK-STAT cascade	5/2112	24/18670	0.1272	0.2913	0.2105	PPP2CA/PTPN2/SOCS1/SOCS2/SH2B3	5
BP	GO:0046639	negative regulation of alpha-beta T cell differentiation	5/2112	24/18670	0.1272	0.2913	0.2105	RUNX3/GLI3/IL4R/SOCS1/TBX21	5
BP	GO:0050687	negative regulation of defense response to virus	5/2112	24/18670	0.1272	0.2913	0.2105	HTRA1/MICB/TSPAN6/TRIM38/IL2RA	5
BP	GO:0051220	cytoplasmic sequestering of protein	5/2112	24/18670	0.1272	0.2913	0.2105	SRI/NFKBIE/DZIP1/NFKBIA/PKD2	5
BP	GO:0060343	trabecula formation	5/2112	24/18670	0.1272	0.2913	0.2105	SFRP1/TGFBR3/RBP4/HEY2/HEY1	5
BP	GO:0062009	secondary palate development	5/2112	24/18670	0.1272	0.2913	0.2105	TGFBR3/LEF1/TGFB3/LRRC32/FZD2	5
BP	GO:0086064	cell communication by electrical coupling involved in cardiac conduction	5/2112	24/18670	0.1272	0.2913	0.2105	SRI/ATP1B1/ATP1A2/SLC8A1/GJC1	5
BP	GO:0090103	cochlea morphogenesis	5/2112	24/18670	0.1272	0.2913	0.2105	SOX9/SIX1/DVL1/MYO3A/FZD2	5
BP	GO:1902410	mitotic cytokinetic process	5/2112	24/18670	0.1272	0.2913	0.2105	CEP55/KIF20A/CHMP2B/KIF20B/CHMP1B	5
BP	GO:1902914	regulation of protein polyubiquitination	5/2112	24/18670	0.1272	0.2913	0.2105	NOD2/DYSF/NMI/UBE2D1/PTPN22	5
BP	GO:2000178	negative regulation of neural precursor cell proliferation	5/2112	24/18670	0.1272	0.2913	0.2105	GATA2/SPINT2/PTN/TP53/LIMS2	5
BP	GO:0008645	hexose transmembrane transport	17/2112	112/18670	0.1276	0.2915	0.2106	ENPP1/PID1/PIK3R1/IGF1/PRKCB/SLC2A6/SLC2A3/PTPN11/SLC2A10/LEP/SLC5A3/ADIPOQ/FABP5/SORBS1/CLIP3/SLC2A5/IL1B	17
BP	GO:0098693	regulation of synaptic vesicle cycle	17/2112	112/18670	0.1276	0.2915	0.2106	PREPL/PRKCB/PFN2/DNM1/MAGI2/PLD1/NLGN1/PCDH17/CDH2/HTR2A/CHRNA5/FGF14/STXBP1/BACE1/DVL1/CASK/P2RY4	17
BP	GO:0003179	heart valve morphogenesis	9/2112	52/18670	0.1277	0.2915	0.2106	BMP4/SOX9/BMPR1A/DCHS1/NOTCH1/HEY2/ACVR1/RB1/HEY1	9
BP	GO:0006301	postreplication repair	9/2112	52/18670	0.1277	0.2915	0.2106	DTL/UBE2L6/UBE2B/REV3L/RFC3/VCP/POLE2/USP10/ISG15	9
BP	GO:0009620	response to fungus	9/2112	52/18670	0.1277	0.2915	0.2106	S100A9/COTL1/GNLY/MALT1/CLEC7A/BAK1/SYK/BTK/PTX3	9
BP	GO:0016447	somatic recombination of immunoglobulin gene segments	9/2112	52/18670	0.1277	0.2915	0.2106	PTPRC/IL27RA/BATF/CD40/TFRC/TBX21/CD40LG/ERCC1/THOC1	9
BP	GO:0046580	negative regulation of Ras protein signal transduction	9/2112	52/18670	0.1277	0.2915	0.2106	RASIP1/TIMP2/DLC1/PPP2CB/TNFAIP1/RASA2/MYOC/KANK1/SCAI	9
BP	GO:0055078	sodium ion homeostasis	9/2112	52/18670	0.1277	0.2915	0.2106	TAC1/SNX5/ATP1B1/AGTR1/ATP1A2/C7/SLC8A1/SLC12A2/EDNRB	9
BP	GO:1990089	response to nerve growth factor	9/2112	52/18670	0.1277	0.2915	0.2106	CORO1A/MICALL1/NTRK2/DYNC1LI2/TAC1/MAGI2/PTN/FOXO3/KIF1B	9
BP	GO:0055088	lipid homeostasis	22/2112	151/18670	0.1287	0.2937	0.2122	ZBTB20/ABCG1/NFE2L1/ACOX2/AKR1C1/NPC1/LRP5/ANGPTL4/LIPG/MYLIP/CETP/RCN3/NR1H3/IL18/FABP4/RALY/CEBPA/ACSM3/LIPC/MED13/EPHX2/SOAT2	22
BP	GO:0002673	regulation of acute inflammatory response	23/2112	159/18670	0.1296	0.2957	0.2136	CLU/CCR7/ADAM8/CFP/HLA-E/PROS1/TAC1/CR1/CD19/IL6ST/IGLC1/IGLV1-44/C7/EDNRB/BTK/IL6/IGHG1/CFB/CD81/IL1B/CR2/C6/NLRP3	23
BP	GO:0002833	positive regulation of response to biotic stimulus	8/2112	45/18670	0.13	0.2964	0.2142	RIPK2/CRTAM/CD160/CD226/DDX60/CD180/CYBA/NOD1	8
BP	GO:0010569	regulation of double-strand break repair via homologous recombination	8/2112	45/18670	0.13	0.2964	0.2142	ZNF365/WAS/PPP4C/TIMELESS/PARP1/RAD51AP1/SMCHD1/ACTR2	8
BP	GO:0090630	activation of GTPase activity	15/2112	97/18670	0.1301	0.2965	0.2142	CXCL13/RASGRP1/TBC1D16/CCR7/TBC1D5/RABGAP1/TBC1D9/CCL21/TBC1D8B/TBC1D1/ARHGEF10/RABGAP1L/GPR65/ECT2/RHOG	15
BP	GO:0009154	purine ribonucleotide catabolic process	6/2112	31/18670	0.1308	0.2972	0.2147	AMPD3/NT5E/PDE1A/ACAT1/NUDT11/HINT1	6
BP	GO:0033198	response to ATP	6/2112	31/18670	0.1308	0.2972	0.2147	SOD1/SLC8A1/RYR3/PANX1/IL1B/P2RY4	6
BP	GO:0033687	osteoblast proliferation	6/2112	31/18670	0.1308	0.2972	0.2147	NELL1/SFRP1/SMAD3/NPR3/ATRAID/ITGAV	6
BP	GO:0040020	regulation of meiotic nuclear division	6/2112	31/18670	0.1308	0.2972	0.2147	UBE2B/DAZL/FBXO5/TTK/CDC20/TRIP13	6
BP	GO:0070306	lens fiber cell differentiation	6/2112	31/18670	0.1308	0.2972	0.2147	CDKN1C/WNT5B/TMOD1/SMAD3/ABI2/CRYGB	6
BP	GO:0090659	walking behavior	6/2112	31/18670	0.1308	0.2972	0.2147	UCHL1/ZIC1/GLRB/OXR1/NPC1/HIPK2	6
BP	GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II	6/2112	31/18670	0.1308	0.2972	0.2147	BMPR1A/GATA2/SMAD3/PRL/SPI1/TP53	6
BP	GO:1903319	positive regulation of protein maturation	6/2112	31/18670	0.1308	0.2972	0.2147	ADAM8/SPON1/BAG2/GSN/IL1B/C6	6
BP	GO:2000781	positive regulation of double-strand break repair	6/2112	31/18670	0.1308	0.2972	0.2147	WAS/TIMELESS/PARP1/SETMAR/SMCHD1/ACTR2	6
BP	GO:0019748	secondary metabolic process	11/2112	67/18670	0.1312	0.2976	0.215	ARL1/FMO2/AKR1C3/CBS/PAM/AKR1B1/AKR1C1/SP1/TRPC1/BDH2/AKR7A2	11
BP	GO:0048662	negative regulation of smooth muscle cell proliferation	11/2112	67/18670	0.1312	0.2976	0.215	TNFAIP3/IGFBP5/IL15/OGN/IFNG/ADIPOQ/TGFB3/PRKG1/ANG/NPR3/NDRG2	11
BP	GO:0006040	amino sugar metabolic process	7/2112	38/18670	0.1313	0.2976	0.215	EXTL2/CHST3/NAGK/GFPT1/FN3K/OVGP1/GFPT2	7
BP	GO:0007223	Wnt signaling pathway, calcium modulating pathway	7/2112	38/18670	0.1313	0.2976	0.215	PPP3CA/TCF7L2/FZD4/LEF1/FZD6/NLK/FZD2	7
BP	GO:0051693	actin filament capping	7/2112	38/18670	0.1313	0.2976	0.215	ADD3/TMOD1/LMOD1/CAPZA1/VILL/SPTBN1/GSN	7
BP	GO:0060416	response to growth hormone	7/2112	38/18670	0.1313	0.2976	0.215	PIK3R1/IGFBP5/JAK2/GHR/SOCS2/PRL/LYN	7
BP	GO:0034644	cellular response to UV	13/2112	82/18670	0.1315	0.298	0.2153	PIK3R1/MFAP4/CREBBP/BAK1/PTN/MAPK13/HYAL1/PARP1/AURKB/CUL4B/ERCC1/PBK/TP53	13
BP	GO:0006643	membrane lipid metabolic process	29/2112	207/18670	0.1321	0.2992	0.2162	PIGK/SERINC3/ALDH3A2/PPP2CA/STS/SGPL1/B3GALNT1/PRKD2/SPHK1/DPM3/GPAA1/GAL3ST4/FA2H/PIGH/FUCA1/SERINC1/PIGP/SGMS1/ELOVL4/GLA/PRKD1/PIGT/ELOVL2/PIGF/UGCG/CERK/ALDH5A1/ELOVL5/CERS4	29
BP	GO:0006637	acyl-CoA metabolic process	16/2112	105/18670	0.1329	0.3008	0.2173	KYNU/PMVK/MPC2/ACAT1/ACACB/HSD17B12/SUCLA2/PDK4/ELOVL4/MPC1/ELOVL2/AASS/ACSM5/ACSM3/ACSL5/ELOVL5	16
BP	GO:0035383	thioester metabolic process	16/2112	105/18670	0.1329	0.3008	0.2173	KYNU/PMVK/MPC2/ACAT1/ACACB/HSD17B12/SUCLA2/PDK4/ELOVL4/MPC1/ELOVL2/AASS/ACSM5/ACSM3/ACSL5/ELOVL5	16
BP	GO:0043244	regulation of protein complex disassembly	17/2112	113/18670	0.1352	0.306	0.2211	ADD3/TMOD1/CKAP2/FGF13/PLEK/ASPH/DSTN/LMOD1/CAMSAP2/MAP1B/CFL1/CAPZA1/VILL/WDR1/FYCO1/SPTBN1/GSN	17
BP	GO:0042475	odontogenesis of dentin-containing tooth	14/2112	90/18670	0.1353	0.306	0.2211	NFIC/BMP4/BCL11B/LRP6/TNFRSF11B/GLI3/FOXC1/TCIRG1/HTRA1/BMPR1A/TP63/LEF1/FOXO1/CA2	14
BP	GO:0006695	cholesterol biosynthetic process	12/2112	75/18670	0.1365	0.3085	0.2229	LBR/ABCG1/PMVK/CYB5R3/ERLIN1/SP1/SOD1/ACACB/SC5D/NFYA/ERLIN2/MBTPS2	12
BP	GO:0050804	modulation of chemical synaptic transmission	57/2112	436/18670	0.1367	0.3088	0.2231	CCR2/LILRB2/NTRK2/PREPL/RAB8A/MCTP1/PPP3CA/PRKCB/PFN2/USP46/LAMA2/JAK2/SNCAIP/DNM1/TUBB2B/EGFR/SLC1A3/TAC1/AKAP12/NLGN1/CX3CR1/CLSTN1/EPHB1/PCDH17/PTN/PLAT/CDH2/PTPRS/HTR2A/CHRNA5/HRH1/CA2/PLK2/KMO/ATP1A2/MECP2/FGF14/ADIPOQ/STX4/VAMP2/STXBP1/PINK1/BACE1/MAP1B/LGI1/CD38/SYBU/SNCG/CDC20/ABHD6/CYP46A1/DVL1/MTMR2/CCL2/CASK/IL1B/P2RY4	57
BP	GO:0042180	cellular ketone metabolic process	34/2112	248/18670	0.1367	0.3088	0.2231	PSMB9/PSMB8/IDO1/NQO1/PSMB10/KYNU/AKR1C3/OXCT1/ACADVL/NFE2L1/CD74/CRYZL1/PSME1/AKR1B1/AKR1C1/ERLIN1/ACACB/GLO1/KMO/RGN/ADIPOQ/ERLIN2/FABP5/PDK4/NDUFA9/DHRS9/NR1H3/CYP46A1/ACADL/HAGH/DKK3/AKR7A2/IL1B/ELOVL5	34
BP	GO:0009141	nucleoside triphosphate metabolic process	48/2112	362/18670	0.1369	0.3092	0.2234	ENPP1/PID1/AMPD3/IGF1/ZBTB20/NDUFC1/BID/ADK/NDUFS2/SLC2A6/CBFA2T3/COX7A1/NUP93/HDAC4/NDUFS4/HK3/NME7/ADA/ALDOC/TPR/CDK1/NDUFA13/NUP160/AK1/HTR2A/ATP1B1/MOCS2/VCP/IFNG/ARNT/CCNB1/ATP1A2/MECP2/MBIP/PARP1/SLC25A23/PINK1/NDUFA9/TYMS/NME4/NUP88/SDHA/NDUFB6/NUP50/TP53/ATP6V1B2/NDUFA4/COX7A2	48
BP	GO:0072522	purine-containing compound biosynthetic process	42/2112	313/18670	0.1372	0.3094	0.2235	PID1/AMPD3/IGF1/NT5E/ZBTB20/ADK/SLC2A6/NPR2/CBFA2T3/SLC26A2/NUP93/HDAC4/HK3/NME7/ADA/ALDOC/MPC2/TPR/ACAT1/NUP160/ACACB/AK1/HTR2A/HSD17B12/VCP/IFNG/ARNT/PNP/PDK4/PARP1/PINK1/ELOVL4/MPC1/GUCA1A/NME4/NUP88/ELOVL2/NUP50/TP53/ACSL5/ELOVL5/PRPS2	42
BP	GO:0042445	hormone metabolic process	32/2112	232/18670	0.1373	0.3094	0.2235	PLEKHA1/AKR1C3/ADH1C/DIO2/SGPL1/AKR1B1/DHRS3/AKR1C1/GHR/TCF7L2/NFKB1/CPE/PTPN11/HSD17B12/RBP4/LEP/IFNG/ARNT/CPQ/MECP2/ADH1B/CPA3/GFI1/HFE/DHRS9/RETSAT/CYP46A1/DIO3/DKK3/REN/IL1B/PCSK7	32
BP	GO:0043401	steroid hormone mediated signaling pathway	26/2112	184/18670	0.1374	0.3094	0.2235	SFRP1/BMP4/RBFOX2/LMO3/AR/KANK2/JAK2/YAP1/TAF7/UFSP2/PGRMC2/TP63/PMEPA1/LEF1/ARNTL/OR51E2/PAK1/PARP1/CALCOCO1/AKAP13/NR1H3/RB1/RWDD1/NRIP1/RNF14/THRA	26
BP	GO:0009124	nucleoside monophosphate biosynthetic process	29/2112	208/18670	0.1378	0.3094	0.2235	PID1/AMPD3/IGF1/ZBTB20/UPP1/ADK/SLC2A6/CBFA2T3/NUP93/HDAC4/HK3/ADA/ALDOC/TPR/NUP160/AK1/HTR2A/VCP/IFNG/ARNT/PARP1/PINK1/TYMS/NUP88/TK2/NUP50/TK1/TP53/PRPS2	29
BP	GO:0046034	ATP metabolic process	41/2112	305/18670	0.1379	0.3094	0.2235	ENPP1/PID1/AMPD3/IGF1/ZBTB20/NDUFC1/BID/NDUFS2/SLC2A6/CBFA2T3/COX7A1/NUP93/HDAC4/NDUFS4/HK3/ALDOC/TPR/CDK1/NDUFA13/NUP160/AK1/HTR2A/ATP1B1/VCP/IFNG/ARNT/CCNB1/ATP1A2/MECP2/PARP1/SLC25A23/PINK1/NDUFA9/NUP88/SDHA/NDUFB6/NUP50/TP53/ATP6V1B2/NDUFA4/COX7A2	41
BP	GO:0010612	regulation of cardiac muscle adaptation	4/2112	18/18670	0.1382	0.3094	0.2235	PPP3CA/FOXO1/SMAD3/LMNA	4
BP	GO:0030809	negative regulation of nucleotide biosynthetic process	4/2112	18/18670	0.1382	0.3094	0.2235	PID1/CBFA2T3/HDAC4/PARP1	4
BP	GO:0034375	high-density lipoprotein particle remodeling	4/2112	18/18670	0.1382	0.3094	0.2235	ABCG1/LIPG/CETP/LIPC	4
BP	GO:0039692	single stranded viral RNA replication via double stranded DNA intermediate	4/2112	18/18670	0.1382	0.3094	0.2235	APOBEC3G/CXCL8/TOP2A/MPHOSPH8	4
BP	GO:0043011	myeloid dendritic cell differentiation	4/2112	18/18670	0.1382	0.3094	0.2235	RELB/BATF/IRF4/SPI1	4
BP	GO:0044320	cellular response to leptin stimulus	4/2112	18/18670	0.1382	0.3094	0.2235	PID1/CCNA2/LEP/UGCG	4
BP	GO:0045683	negative regulation of epidermis development	4/2112	18/18670	0.1382	0.3094	0.2235	EZH2/TP63/NOTCH1/FERMT1	4
BP	GO:0051782	negative regulation of cell division	4/2112	18/18670	0.1382	0.3094	0.2235	ASPM/BLM/E2F8/AURKB	4
BP	GO:0060749	mammary gland alveolus development	4/2112	18/18670	0.1382	0.3094	0.2235	AR/SOCS2/CCND1/HOXA5	4
BP	GO:0060977	coronary vasculature morphogenesis	4/2112	18/18670	0.1382	0.3094	0.2235	TGFBR3/SGCD/NOTCH1/HEY2	4
BP	GO:0061377	mammary gland lobule development	4/2112	18/18670	0.1382	0.3094	0.2235	AR/SOCS2/CCND1/HOXA5	4
BP	GO:0071371	cellular response to gonadotropin stimulus	4/2112	18/18670	0.1382	0.3094	0.2235	INHBA/CCNA2/EFNA5/NOTCH1	4
BP	GO:0072077	renal vesicle morphogenesis	4/2112	18/18670	0.1382	0.3094	0.2235	BMP4/STAT1/SOX9/SIX2	4
BP	GO:0097094	craniofacial suture morphogenesis	4/2112	18/18670	0.1382	0.3094	0.2235	BMP4/GLI3/TGFB3/MEGF8	4
BP	GO:0150078	positive regulation of neuroinflammatory response	4/2112	18/18670	0.1382	0.3094	0.2235	CTSC/IL6/IL18/IL1B	4
BP	GO:1900372	negative regulation of purine nucleotide biosynthetic process	4/2112	18/18670	0.1382	0.3094	0.2235	PID1/CBFA2T3/HDAC4/PARP1	4
BP	GO:1903242	regulation of cardiac muscle hypertrophy in response to stress	4/2112	18/18670	0.1382	0.3094	0.2235	PPP3CA/FOXO1/SMAD3/LMNA	4
BP	GO:1905276	regulation of epithelial tube formation	4/2112	18/18670	0.1382	0.3094	0.2235	SFRP1/SIX1/DVL1/FZD2	4
BP	GO:2000647	negative regulation of stem cell proliferation	4/2112	18/18670	0.1382	0.3094	0.2235	PTN/FBLN1/FERMT1/TP53	4
BP	GO:0031124	mRNA 3'-end processing	15/2112	98/18670	0.1385	0.3098	0.2239	CPEB1/CPSF6/BARD1/CCNT1/AHCYL1/CSTF2/ZFP36L1/CCNB1/THOC2/PAF1/DDX39A/RPRD1A/CLP1/THOC1/THOC6	15
BP	GO:0035065	regulation of histone acetylation	9/2112	53/18670	0.1393	0.3114	0.225	NAP1L2/AUTS2/GATA2/KMT2A/TAF7/RPS6KA4/EID1/SPI1/IL1B	9
BP	GO:0071320	cellular response to cAMP	9/2112	53/18670	0.1393	0.3114	0.225	IGFBP5/PENK/AQP9/PCK1/NOX4/ZFP36L1/SLC8A1/ADIPOQ/PKD2	9
BP	GO:0034605	cellular response to heat	20/2112	137/18670	0.1401	0.3131	0.2262	IER5/CRYAB/NUP93/CXCL10/TFEC/CREBBP/HSPA6/TPR/BAG2/NUP160/VCP/HSP90AB1/DNAJC7/MAPKAPK2/LYN/HSPA1L/NUP88/BAG5/NUP50/DNAJC2	20
BP	GO:0042742	defense response to bacterium	44/2112	330/18670	0.1403	0.3134	0.2265	CXCL13/SLAMF8/TRBC1/S100A9/IL27RA/GBP2/SLPI/MYD88/IRF8/TLR2/GNLY/NOD2/COCH/CD36/CFP/LYZ/PLAC8/ANXA3/TNFRSF14/RIPK2/FGR/HLA-E/IGHM/IGLL5/CD160/CLEC4E/TLR5/IGLC1/KRT6A/SYK/IL6/IGHG1/HP/CXCL6/FPR2/CYBA/PPP1R11/NOD1/SPINK5/STAB2/RAB14/ISG15/TLR6/NLRP3	44
BP	GO:0000077	DNA damage checkpoint	21/2112	145/18670	0.1411	0.3147	0.2274	TFDP2/DTL/PLK1/CDC14B/BLM/E2F8/CDK1/PTPN11/PLK2/DONSON/CCNB1/CCND1/CEP63/SYF2/THOC1/PRMT1/PCBP4/WAC/TP53/AURKA/PML	21
BP	GO:0033866	nucleoside bisphosphate biosynthetic process	11/2112	68/18670	0.1415	0.3147	0.2274	SLC26A2/MPC2/ACAT1/ACACB/HSD17B12/PDK4/ELOVL4/MPC1/ELOVL2/ACSL5/ELOVL5	11
BP	GO:0034030	ribonucleoside bisphosphate biosynthetic process	11/2112	68/18670	0.1415	0.3147	0.2274	SLC26A2/MPC2/ACAT1/ACACB/HSD17B12/PDK4/ELOVL4/MPC1/ELOVL2/ACSL5/ELOVL5	11
BP	GO:0034033	purine nucleoside bisphosphate biosynthetic process	11/2112	68/18670	0.1415	0.3147	0.2274	SLC26A2/MPC2/ACAT1/ACACB/HSD17B12/PDK4/ELOVL4/MPC1/ELOVL2/ACSL5/ELOVL5	11
BP	GO:0071230	cellular response to amino acid stimulus	11/2112	68/18670	0.1415	0.3147	0.2274	NTRK2/SIX1/PDGFD/SOCS1/EGFR/CPEB1/DNMT1/BCL11A/CYBA/SESN1/COL16A1	11
BP	GO:0005978	glycogen biosynthetic process	8/2112	46/18670	0.1427	0.3147	0.2274	ENPP1/IGF1/PPP1R3C/PASK/PER2/PPP1CA/SORBS1/UGP2	8
BP	GO:0006984	ER-nucleus signaling pathway	8/2112	46/18670	0.1427	0.3147	0.2274	PTPN2/CXCL8/ERLIN1/ERLIN2/DDIT3/MBTPS2/TP53/CCL2	8
BP	GO:0009250	glucan biosynthetic process	8/2112	46/18670	0.1427	0.3147	0.2274	ENPP1/IGF1/PPP1R3C/PASK/PER2/PPP1CA/SORBS1/UGP2	8
BP	GO:0031648	protein destabilization	8/2112	46/18670	0.1427	0.3147	0.2274	PLK1/CHFR/CREBBP/CCDC88C/TRIM21/MYLIP/GSN/CTSH	8
BP	GO:0043330	response to exogenous dsRNA	8/2112	46/18670	0.1427	0.3147	0.2274	RFTN1/IFIH1/RIPK2/NFKBIA/DDX58/COLEC12/DDX1/IFNA1	8
BP	GO:0060443	mammary gland morphogenesis	8/2112	46/18670	0.1427	0.3147	0.2274	BMP4/IGFBP5/LRP6/GLI3/AR/ETV5/LRP5/PML	8
BP	GO:1900015	regulation of cytokine production involved in inflammatory response	8/2112	46/18670	0.1427	0.3147	0.2274	MYD88/NOD2/GPSM3/CLEC7A/C5orf30/CD6/LEP/TLR6	8
BP	GO:0034968	histone lysine methylation	17/2112	114/18670	0.1431	0.3147	0.2274	AUTS2/KMT2A/EZH2/DNMT1/ATRX/BRD4/PAX5/MECP2/MTF2/RLF/GFI1/SUZ12/SMYD2/JARID2/LMNA/SETMAR/EZH1	17
BP	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	18/2112	122/18670	0.1449	0.3147	0.2274	CLU/CBFA2T3/PLK1/CHFR/PLK2/VCP/HSP90AB1/HFE/RNF19B/CEBPA/DVL1/BAG5/WAC/PBK/USP7/CAMLG/AURKA/RNF14	18
BP	GO:1903844	regulation of cellular response to transforming growth factor beta stimulus	18/2112	122/18670	0.1449	0.3147	0.2274	CDKN1C/SKI/HTRA1/ADAMTSL2/TGFBR3/CREBBP/GLG1/CHST11/PMEPA1/SMAD3/LDLRAD4/HSP90AB1/TGFB3/FERMT1/HIPK2/DKK3/CFLAR/TP53	18
BP	GO:0009404	toxin metabolic process	5/2112	25/18670	0.145	0.3147	0.2274	ARL1/FMO2/CBS/PAM/SP1	5
BP	GO:0014829	vascular smooth muscle contraction	5/2112	25/18670	0.145	0.3147	0.2274	COMP/HTR2A/SLC8A1/EDNRB/CD38	5
BP	GO:0021952	central nervous system projection neuron axonogenesis	5/2112	25/18670	0.145	0.3147	0.2274	TSKU/NFIB/EPHB1/SCN1B/DCLK1	5
BP	GO:0030325	adrenal gland development	5/2112	25/18670	0.145	0.3147	0.2274	CDKN1C/PBX1/SMAD3/FSTL3/DKK3	5
BP	GO:0030813	positive regulation of nucleotide catabolic process	5/2112	25/18670	0.145	0.3147	0.2274	IGF1/ZBTB20/HTR2A/IFNG/ARNT	5
BP	GO:0035336	long-chain fatty-acyl-CoA metabolic process	5/2112	25/18670	0.145	0.3147	0.2274	HSD17B12/ELOVL4/ELOVL2/ACSL5/ELOVL5	5
BP	GO:0051156	glucose 6-phosphate metabolic process	5/2112	25/18670	0.145	0.3147	0.2274	NFE2L1/HK3/RPIA/PGD/TALDO1	5
BP	GO:0051197	positive regulation of coenzyme metabolic process	5/2112	25/18670	0.145	0.3147	0.2274	IGF1/ZBTB20/HTR2A/IFNG/ARNT	5
BP	GO:0060444	branching involved in mammary gland duct morphogenesis	5/2112	25/18670	0.145	0.3147	0.2274	LRP6/AR/ETV5/LRP5/PML	5
BP	GO:0072273	metanephric nephron morphogenesis	5/2112	25/18670	0.145	0.3147	0.2274	BMP4/STAT1/SOX9/SIX2/PKD2	5
BP	GO:1903306	negative regulation of regulated secretory pathway	5/2112	25/18670	0.145	0.3147	0.2274	CCR2/HLA-F/LGALS9/IL13RA2/NOTCH1	5
BP	GO:1904385	cellular response to angiotensin	5/2112	25/18670	0.145	0.3147	0.2274	AHCYL1/NFKB1/CA2/AGTR1/CYBA	5
BP	GO:2000679	positive regulation of transcription regulatory region DNA binding	5/2112	25/18670	0.145	0.3147	0.2274	IGF1/FOXC1/IFNG/PARP1/RB1	5
BP	GO:0007257	activation of JUN kinase activity	7/2112	39/18670	0.1454	0.3147	0.2274	CCL19/MAP3K11/RIPK2/MAP4K1/CD40LG/MAP3K2/SYK	7
BP	GO:0033146	regulation of intracellular estrogen receptor signaling pathway	7/2112	39/18670	0.1454	0.3147	0.2274	AR/KANK2/YAP1/UFSP2/TP63/PAK1/PARP1	7
BP	GO:0055090	acylglycerol homeostasis	7/2112	39/18670	0.1454	0.3147	0.2274	ANGPTL4/LIPG/CETP/NR1H3/IL18/LIPC/MED13	7
BP	GO:0070328	triglyceride homeostasis	7/2112	39/18670	0.1454	0.3147	0.2274	ANGPTL4/LIPG/CETP/NR1H3/IL18/LIPC/MED13	7
BP	GO:0072529	pyrimidine-containing compound catabolic process	7/2112	39/18670	0.1454	0.3147	0.2274	TYMP/NT5E/UPP1/APOBEC3G/ALDH6A1/APOBEC3B/ENTPD4	7
BP	GO:0072595	maintenance of protein localization in organelle	7/2112	39/18670	0.1454	0.3147	0.2274	SKP1/BARD1/GPAA1/KDELR3/KDELR2/PINK1/PML	7
BP	GO:1901998	toxin transport	7/2112	39/18670	0.1454	0.3147	0.2274	LRP6/ABCG1/ANTXR1/DNM1/RAB40B/LRP5/RAB28	7
BP	GO:1905521	regulation of macrophage migration	7/2112	39/18670	0.1454	0.3147	0.2274	CCL5/SLAMF8/CD200/CX3CR1/CD9/MTUS1/CD81	7
BP	GO:2000826	regulation of heart morphogenesis	7/2112	39/18670	0.1454	0.3147	0.2274	BMP4/SOX9/PIM1/FOXC1/SIX1/NOTCH1/ACVR1	7
BP	GO:0006997	nucleus organization	19/2112	130/18670	0.1463	0.3147	0.2274	TMEM43/PPP2CA/NFE2L1/PRKCB/CCNB2/VRK1/PLK1/NUP93/SRPK1/TPR/CDK1/ZPR1/TOR1AIP1/CCNB1/CHMP2B/LMNA/HIPK2/CHMP1B/PML	19
BP	GO:0042157	lipoprotein metabolic process	19/2112	130/18670	0.1463	0.3147	0.2274	PIGK/APOL1/APOL6/APOL3/DPM3/GPAA1/PIGH/LIPG/LEP/ZDHHC18/PIGP/CLIP3/APOLD1/PIGT/GOLGA7/PIGF/UGCG/ITGAV/ZDHHC14	19
BP	GO:0060411	cardiac septum morphogenesis	12/2112	76/18670	0.1464	0.3147	0.2274	BMP4/ZFPM2/BMPR1A/DHRS3/TGFBR3/PARVA/NOTCH1/HEY2/ACVR1/HEY1/FZD2/TP53	12
BP	GO:1901264	carbohydrate derivative transport	12/2112	76/18670	0.1464	0.3147	0.2274	SLC17A5/ABCG1/SLC29A1/ADA/SLC37A1/SLC25A4/SLC25A23/SLC29A2/RALBP1/CYBA/SLC25A5/SLC35A2	12
BP	GO:1902653	secondary alcohol biosynthetic process	12/2112	76/18670	0.1464	0.3147	0.2274	LBR/ABCG1/PMVK/CYB5R3/ERLIN1/SP1/SOD1/ACACB/SC5D/NFYA/ERLIN2/MBTPS2	12
BP	GO:0002371	dendritic cell cytokine production	3/2112	12/18670	0.1465	0.3147	0.2274	NOD2/DDX58/DDX1	3
BP	GO:0002551	mast cell chemotaxis	3/2112	12/18670	0.1465	0.3147	0.2274	RAC2/PIK3CD/VEGFB	3
BP	GO:0002903	negative regulation of B cell apoptotic process	3/2112	12/18670	0.1465	0.3147	0.2274	CD74/ADA/AURKB	3
BP	GO:0002921	negative regulation of humoral immune response	3/2112	12/18670	0.1465	0.3147	0.2274	PTPN6/CR1/SPINK5	3
BP	GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis	3/2112	12/18670	0.1465	0.3147	0.2274	BMP4/STAT1/SIX2	3
BP	GO:0006020	inositol metabolic process	3/2112	12/18670	0.1465	0.3147	0.2274	MECP2/SLC5A3/PPIP5K1	3
BP	GO:0006069	ethanol oxidation	3/2112	12/18670	0.1465	0.3147	0.2274	ADH1C/ADH1B/ADH5	3
BP	GO:0006527	arginine catabolic process	3/2112	12/18670	0.1465	0.3147	0.2274	FAH/OAT/DDAH2	3
BP	GO:0006563	L-serine metabolic process	3/2112	12/18670	0.1465	0.3147	0.2274	SERINC3/CBS/PSPH	3
BP	GO:0006568	tryptophan metabolic process	3/2112	12/18670	0.1465	0.3147	0.2274	IDO1/KYNU/KMO	3
BP	GO:0006991	response to sterol depletion	3/2112	12/18670	0.1465	0.3147	0.2274	ERLIN1/ERLIN2/LYN	3
BP	GO:0007288	sperm axoneme assembly	3/2112	12/18670	0.1465	0.3147	0.2274	UBE2B/TTLL1/SPAG16	3
BP	GO:0009886	post-embryonic animal morphogenesis	3/2112	12/18670	0.1465	0.3147	0.2274	BAK1/EFEMP1/ATRX	3
BP	GO:0010452	histone H3-K36 methylation	3/2112	12/18670	0.1465	0.3147	0.2274	BRD4/SMYD2/SETMAR	3
BP	GO:0014029	neural crest formation	3/2112	12/18670	0.1465	0.3147	0.2274	SFRP1/LRP6/SOX9	3
BP	GO:0015867	ATP transport	3/2112	12/18670	0.1465	0.3147	0.2274	SLC25A4/SLC25A23/SLC25A5	3
BP	GO:0021559	trigeminal nerve development	3/2112	12/18670	0.1465	0.3147	0.2274	SEMA3A/SEMA3F/TFAP2A	3
BP	GO:0031392	regulation of prostaglandin biosynthetic process	3/2112	12/18670	0.1465	0.3147	0.2274	CD74/FABP5/IL1B	3
BP	GO:0032230	positive regulation of synaptic transmission, GABAergic	3/2112	12/18670	0.1465	0.3147	0.2274	TAC1/NLGN1/CA2	3
BP	GO:0032252	secretory granule localization	3/2112	12/18670	0.1465	0.3147	0.2274	RASGRP1/SYBU/KIF1B	3
BP	GO:0032429	regulation of phospholipase A2 activity	3/2112	12/18670	0.1465	0.3147	0.2274	EGFR/AGTR1/ANG	3
BP	GO:0034086	maintenance of sister chromatid cohesion	3/2112	12/18670	0.1465	0.3147	0.2274	ATRX/NIPBL/RB1	3
BP	GO:0034088	maintenance of mitotic sister chromatid cohesion	3/2112	12/18670	0.1465	0.3147	0.2274	ATRX/NIPBL/RB1	3
BP	GO:0034372	very-low-density lipoprotein particle remodeling	3/2112	12/18670	0.1465	0.3147	0.2274	LIPG/CETP/LIPC	3
BP	GO:0035437	maintenance of protein localization in endoplasmic reticulum	3/2112	12/18670	0.1465	0.3147	0.2274	GPAA1/KDELR3/KDELR2	3
BP	GO:0036005	response to macrophage colony-stimulating factor	3/2112	12/18670	0.1465	0.3147	0.2274	TLR2/PTPN2/FER	3
BP	GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	3/2112	12/18670	0.1465	0.3147	0.2274	TLR2/PTPN2/FER	3
BP	GO:0042308	negative regulation of protein import into nucleus	3/2112	12/18670	0.1465	0.3147	0.2274	ANGPT1/CD36/FERMT1	3
BP	GO:0044650	adhesion of symbiont to host cell	3/2112	12/18670	0.1465	0.3147	0.2274	ICAM1/HSP90AB1/CD81	3
BP	GO:0045080	positive regulation of chemokine biosynthetic process	3/2112	12/18670	0.1465	0.3147	0.2274	CD74/IFNG/IL1B	3
BP	GO:0048934	peripheral nervous system neuron differentiation	3/2112	12/18670	0.1465	0.3147	0.2274	RUNX3/NTRK2/HOXD10	3
BP	GO:0048935	peripheral nervous system neuron development	3/2112	12/18670	0.1465	0.3147	0.2274	RUNX3/NTRK2/HOXD10	3
BP	GO:0051132	NK T cell activation	3/2112	12/18670	0.1465	0.3147	0.2274	IL15/ELF4/IL18	3
BP	GO:0051549	positive regulation of keratinocyte migration	3/2112	12/18670	0.1465	0.3147	0.2274	FGF7/MAPRE2/HBEGF	3
BP	GO:0051608	histamine transport	3/2112	12/18670	0.1465	0.3147	0.2274	ADA/BTK/LYN	3
BP	GO:0060019	radial glial cell differentiation	3/2112	12/18670	0.1465	0.3147	0.2274	GLI3/CDH2/LEF1	3
BP	GO:0060742	epithelial cell differentiation involved in prostate gland development	3/2112	12/18670	0.1465	0.3147	0.2274	AR/TP63/NOTCH1	3
BP	GO:0070493	thrombin-activated receptor signaling pathway	3/2112	12/18670	0.1465	0.3147	0.2274	PLEK/GP1BA/IQGAP2	3
BP	GO:0070572	positive regulation of neuron projection regeneration	3/2112	12/18670	0.1465	0.3147	0.2274	HGF/SCARF1/PTN	3
BP	GO:0071073	positive regulation of phospholipid biosynthetic process	3/2112	12/18670	0.1465	0.3147	0.2274	HTR2B/HTR2A/FPR2	3
BP	GO:0071340	skeletal muscle acetylcholine-gated channel clustering	3/2112	12/18670	0.1465	0.3147	0.2274	ETV5/PTN/DVL1	3
BP	GO:0071481	cellular response to X-ray	3/2112	12/18670	0.1465	0.3147	0.2274	SFRP1/NUCKS1/NIPBL	3
BP	GO:0071679	commissural neuron axon guidance	3/2112	12/18670	0.1465	0.3147	0.2274	DAG1/NFIB/RYK	3
BP	GO:0072017	distal tubule development	3/2112	12/18670	0.1465	0.3147	0.2274	NOTCH1/PKD2/POU3F3	3
BP	GO:0072520	seminiferous tubule development	3/2112	12/18670	0.1465	0.3147	0.2274	AR/ATRX/REC8	3
BP	GO:0072710	response to hydroxyurea	3/2112	12/18670	0.1465	0.3147	0.2274	BLM/ATRX/TIMELESS	3
BP	GO:0090148	membrane fission	3/2112	12/18670	0.1465	0.3147	0.2274	MX2/MX1/TMCC1	3
BP	GO:0090161	Golgi ribbon formation	3/2112	12/18670	0.1465	0.3147	0.2274	GOLGA2/STX16/STX6	3
BP	GO:0090331	negative regulation of platelet aggregation	3/2112	12/18670	0.1465	0.3147	0.2274	CD9/PRKG1/SH2B3	3
BP	GO:0090520	sphingolipid mediated signaling pathway	3/2112	12/18670	0.1465	0.3147	0.2274	SPHK1/S1PR1/S1PR4	3
BP	GO:0097104	postsynaptic membrane assembly	3/2112	12/18670	0.1465	0.3147	0.2274	MAGI2/NLGN1/CDH2	3
BP	GO:0097531	mast cell migration	3/2112	12/18670	0.1465	0.3147	0.2274	RAC2/PIK3CD/VEGFB	3
BP	GO:0150065	regulation of deacetylase activity	3/2112	12/18670	0.1465	0.3147	0.2274	PRKD2/PINK1/PRKD1	3
BP	GO:1900165	negative regulation of interleukin-6 secretion	3/2112	12/18670	0.1465	0.3147	0.2274	IL27RA/CD200/PTPN22	3
BP	GO:1901298	regulation of hydrogen peroxide-mediated programmed cell death	3/2112	12/18670	0.1465	0.3147	0.2274	HGF/PINK1/FOXO3	3
BP	GO:1902337	regulation of apoptotic process involved in morphogenesis	3/2112	12/18670	0.1465	0.3147	0.2274	TNFRSF1B/FOXC1/NOTCH1	3
BP	GO:1903909	regulation of receptor clustering	3/2112	12/18670	0.1465	0.3147	0.2274	PTN/CD81/GSN	3
BP	GO:1904590	negative regulation of protein import	3/2112	12/18670	0.1465	0.3147	0.2274	ANGPT1/CD36/FERMT1	3
BP	GO:0048645	animal organ formation	10/2112	61/18670	0.1465	0.3147	0.2274	BMP4/PIM1/GLI3/AR/SULF1/SIX1/BMPR1A/SMARCD3/TP63/HOXA11	10
BP	GO:0003176	aortic valve development	6/2112	32/18670	0.1465	0.3147	0.2274	BMP4/TNFRSF1B/SOX9/NOTCH1/HEY2/RB1	6
BP	GO:0031297	replication fork processing	6/2112	32/18670	0.1465	0.3147	0.2274	NUCKS1/ZNF365/BLM/ATRX/THOC1/SETMAR	6
BP	GO:0035587	purinergic receptor signaling pathway	6/2112	32/18670	0.1465	0.3147	0.2274	ADA/GPR171/ADORA3/P2RY6/P2RY14/P2RY4	6
BP	GO:0042744	hydrogen peroxide catabolic process	6/2112	32/18670	0.1465	0.3147	0.2274	HBB/GPX3/HBD/PRDX6/HP/CAT	6
BP	GO:0046685	response to arsenic-containing substance	6/2112	32/18670	0.1465	0.3147	0.2274	TNFRSF11B/MAPK13/VCP/ZFAND1/GSTO1/ALAD	6
BP	GO:0046949	fatty-acyl-CoA biosynthetic process	6/2112	32/18670	0.1465	0.3147	0.2274	ACAT1/HSD17B12/ELOVL4/ELOVL2/ACSL5/ELOVL5	6
BP	GO:0051968	positive regulation of synaptic transmission, glutamatergic	6/2112	32/18670	0.1465	0.3147	0.2274	CCR2/EGFR/NLGN1/KMO/STXBP1/CCL2	6
BP	GO:0060317	cardiac epithelial to mesenchymal transition	6/2112	32/18670	0.1465	0.3147	0.2274	TGFBR3/TMEM100/NOTCH1/HEY2/ACVR1/HEY1	6
BP	GO:1900745	positive regulation of p38MAPK cascade	6/2112	32/18670	0.1465	0.3147	0.2274	SPHK1/MFHAS1/LEP/NCF1/PRMT1/IL1B	6
BP	GO:1901661	quinone metabolic process	6/2112	32/18670	0.1465	0.3147	0.2274	AKR1C3/CRYZL1/AKR1B1/AKR1C1/NDUFA9/AKR7A2	6
BP	GO:1904467	regulation of tumor necrosis factor secretion	6/2112	32/18670	0.1465	0.3147	0.2274	IL27RA/LGALS9/IFIH1/AKAP12/DDX58/IFNG	6
BP	GO:0061337	cardiac conduction	21/2112	146/18670	0.1482	0.3183	0.23	SRI/CACNA2D1/ANK2/KCNK1/NPR2/FXYD1/FXYD6/KCNJ5/AHCYL1/PLN/ASPH/KCNJ2/TRPC1/ATP1B1/SCN1B/DSC2/ATP1A2/SLC8A1/RYR3/GJC1/ATP2A3	21
BP	GO:0009746	response to hexose	28/2112	202/18670	0.1497	0.3214	0.2322	ZBTB20/SRI/OXCT1/PPP3CA/ICAM1/KLF7/MPC2/TCF7L2/PCK1/LRP5/NOX4/RMI1/EFNA5/PIK3CA/SLC8A1/ADIPOQ/STX4/VAMP2/NDUFA9/SYBU/FOXO3/ENSA/CYBA/RAB11FIP2/SLC2A5/ZNF236/GPR27/TXN2	28
BP	GO:0014910	regulation of smooth muscle cell migration	13/2112	84/18670	0.1503	0.3223	0.2328	CCL5/IGFBP5/IGF1/LPAR1/BMPR1A/PDGFD/HDAC4/NOX4/PAK1/ADIPOQ/P2RY6/FGF9/PRKG1	13
BP	GO:0046889	positive regulation of lipid biosynthetic process	13/2112	84/18670	0.1503	0.3223	0.2328	ZBTB20/ABCG1/CD74/HTR2B/HTR2A/IFNG/RGN/SORBS1/NR1H3/FPR2/ABHD6/IL1B/ELOVL5	13
BP	GO:0097756	negative regulation of blood vessel diameter	13/2112	84/18670	0.1503	0.3223	0.2328	ICAM1/COMP/HTR2B/EGFR/PER2/HTR2A/HRH1/LEP/AGTR1/ATP1A2/SLC8A1/EDNRB/CD38	13
BP	GO:1901293	nucleoside phosphate biosynthetic process	51/2112	390/18670	0.1514	0.3243	0.2343	PID1/AMPD3/IGF1/IDO1/ZBTB20/KYNU/UPP1/ADK/SLC2A6/NPR2/CBFA2T3/SLC26A2/RRM2/NUP93/HDAC4/HK3/NME7/ADA/ALDOC/MPC2/IDH2/TPR/ACAT1/NUP160/ACACB/AK1/HTR2A/HSD17B12/VCP/IFNG/ARNT/KMO/PNP/PDK4/PARP1/PINK1/ELOVL4/TYMS/MPC1/GUCA1A/NME4/NUP88/ELOVL2/TK2/NUP50/TK1/TP53/ACSL5/AK6/ELOVL5/PRPS2	51
BP	GO:0070206	protein trimerization	9/2112	54/18670	0.1514	0.3243	0.2343	CD247/SKI/CD74/SIGMAR1/HLA-G/TRIM21/ADIPOQ/TRIM22/ATXN10	9
BP	GO:2000243	positive regulation of reproductive process	11/2112	69/18670	0.1522	0.3259	0.2354	SOX9/SEMA3A/INHBA/AR/ZFPM2/HDAC4/UBE2B/CDC25B/DAZL/EDNRB/AURKA	11
BP	GO:0009199	ribonucleoside triphosphate metabolic process	45/2112	341/18670	0.1533	0.3282	0.2371	ENPP1/PID1/AMPD3/IGF1/ZBTB20/NDUFC1/BID/NDUFS2/SLC2A6/CBFA2T3/COX7A1/NUP93/HDAC4/NDUFS4/HK3/NME7/ALDOC/TPR/CDK1/NDUFA13/NUP160/AK1/HTR2A/ATP1B1/MOCS2/VCP/IFNG/ARNT/CCNB1/ATP1A2/MECP2/MBIP/PARP1/SLC25A23/PINK1/NDUFA9/NME4/NUP88/SDHA/NDUFB6/NUP50/TP53/ATP6V1B2/NDUFA4/COX7A2	45
BP	GO:0006164	purine nucleotide biosynthetic process	40/2112	300/18670	0.1534	0.3282	0.2371	PID1/AMPD3/IGF1/ZBTB20/ADK/SLC2A6/NPR2/CBFA2T3/SLC26A2/NUP93/HDAC4/HK3/NME7/ADA/ALDOC/MPC2/TPR/ACAT1/NUP160/ACACB/AK1/HTR2A/HSD17B12/VCP/IFNG/ARNT/PDK4/PARP1/PINK1/ELOVL4/MPC1/GUCA1A/NME4/NUP88/ELOVL2/NUP50/TP53/ACSL5/ELOVL5/PRPS2	40
BP	GO:0019319	hexose biosynthetic process	14/2112	92/18670	0.1535	0.3283	0.2372	CHST15/PTPN2/AKR1B1/ALDOC/PC/SIK1/PCK1/PER2/FAM3C/FOXO1/RBP4/LEP/ADIPOQ/MDH1	14
BP	GO:0045833	negative regulation of lipid metabolic process	14/2112	92/18670	0.1535	0.3283	0.2372	AKR1C3/ACADVL/SPHK1/SIK1/ERLIN1/SOD1/ACACB/NFKB1/ERLIN2/GFI1/ACADL/PDE3B/DKK3/IL1B	14
BP	GO:0046887	positive regulation of hormone secretion	19/2112	131/18670	0.154	0.3292	0.2378	SRI/INHBA/OXCT1/JAK2/ITSN1/EGFR/TM7SF3/TAC1/MPC2/NMB/TCF7L2/PTPN11/RBP4/LEP/STX4/HFE/CD38/SYBU/GPR27	19
BP	GO:0009410	response to xenobiotic stimulus	39/2112	292/18670	0.1543	0.3297	0.2382	CDO1/PENK/NQO1/CXCR4/EPHX1/FMO2/GSTM5/PPP3CA/GSTM3/GSTA4/ICAM1/SLC18A2/BPHL/EGFR/CYB5R3/ADA/AKR1C1/TAC1/GHR/CCNA2/PCK1/SOD1/HTR2A/FOXO1/ARNT/SLC8A1/HSP90AB1/AOC2/PTGS1/RYR3/FOXO3/RB1/CYP46A1/GSTO1/AOC3/CFLAR/GSTM2/AKR7A2/EPHX2	39
BP	GO:0051588	regulation of neurotransmitter transport	20/2112	139/18670	0.1549	0.3309	0.2391	PREPL/MCTP1/PRKCB/PFN2/SNCAIP/NLGN1/PER2/ARL6IP5/HTR2A/CHRNA5/KMO/ATP1A2/STXBP1/BACE1/MAOB/SNCG/DVL1/CASK/P2RY4/LILRB1	20
BP	GO:0008206	bile acid metabolic process	8/2112	47/18670	0.156	0.3325	0.2402	ACOX2/AKR1C1/NPC1/LEP/OSBPL1A/SLC27A5/CYP46A1/OSBPL9	8
BP	GO:0042551	neuron maturation	8/2112	47/18670	0.156	0.3325	0.2402	CDKN1C/SCARF1/IRX5/MYOC/MECP2/EDNRB/BCL11A/RB1	8
BP	GO:0047496	vesicle transport along microtubule	8/2112	47/18670	0.156	0.3325	0.2402	RASGRP1/TRAK2/KIF3B/DYNC1I1/SYBU/FYCO1/KIF1B/KIF23	8
BP	GO:0048066	developmental pigmentation	8/2112	47/18670	0.156	0.3325	0.2402	ENPP1/KITLG/MREG/GLI3/LEF1/RAB27A/OR51E2/EDNRB	8
BP	GO:0050435	amyloid-beta metabolic process	8/2112	47/18670	0.156	0.3325	0.2402	IGF1/CLU/ABCG1/SPON1/IFNG/BACE1/ADAM10/REN	8
BP	GO:1903115	regulation of actin filament-based movement	8/2112	47/18670	0.156	0.3325	0.2402	SRI/ANK2/PDPN/FGF13/PLN/KCNJ2/DSC2/ATP1A2	8
BP	GO:0022600	digestive system process	15/2112	100/18670	0.156	0.3325	0.2402	TYMP/SERPINA3/SOX9/NOD2/CD36/AKR1C1/TAC1/RBP4/LEP/NR1H3/SNX10/NPR3/UGCG/SLC2A5/SOAT2	15
BP	GO:0035282	segmentation	15/2112	100/18670	0.156	0.3325	0.2402	SFRP1/BMP4/LRP6/FOXC1/SEMA3A/BMPR1A/COBL/MEOX1/LEF1/SEMA3F/SMAD3/NOTCH1/MTF2/NLE1/TP53	15
BP	GO:0016575	histone deacetylation	12/2112	77/18670	0.1566	0.3335	0.241	SKI/SIRT7/HDAC4/PRKD2/PER2/MSL3/NIPBL/PINK1/MORF4L1/PRKD1/TP53/TBL1X	12
BP	GO:0051851	modification by host of symbiont morphology or physiology	12/2112	77/18670	0.1566	0.3335	0.241	CCL5/NUCKS1/CHD1/PC/IFI27/CCNT1/SP1/LEF1/FBXL2/CFL1/CXCL6/PTX3	12
BP	GO:0003407	neural retina development	10/2112	62/18670	0.158	0.3359	0.2427	SOX9/SMARCD3/PTN/IRX5/TFAP2A/ZHX2/HIPK2/DIO3/ROM1/AHI1	10
BP	GO:0031640	killing of cells of other organism	10/2112	62/18670	0.158	0.3359	0.2427	PRF1/APOL1/CCL13/GNLY/LYZ/CLEC7A/IFNG/KRT6A/SYK/CXCL6	10
BP	GO:0044364	disruption of cells of other organism	10/2112	62/18670	0.158	0.3359	0.2427	PRF1/APOL1/CCL13/GNLY/LYZ/CLEC7A/IFNG/KRT6A/SYK/CXCL6	10
BP	GO:1901862	negative regulation of muscle tissue development	10/2112	62/18670	0.158	0.3359	0.2427	BMP4/IGFBP5/MEIS1/KCNK2/EPHB1/LEF1/FZD7/RBP4/PAK1/JARID2	10
BP	GO:0060071	Wnt signaling pathway, planar cell polarity pathway	16/2112	108/18670	0.1581	0.3359	0.2427	PSMB9/SFRP1/PSMB8/PSMB10/PSME1/MAGI2/RYK/PLEKHA4/FZD4/FZD7/DACT1/GPC4/FZD6/DVL1/FZD2/PFN1	16
BP	GO:0071156	regulation of cell cycle arrest	16/2112	108/18670	0.1581	0.3359	0.2427	TFDP2/CRLF3/EVI2B/E2F8/CDK1/PLK2/CCNB1/HSP90AB1/CCND1/PKD2/PRMT1/SETMAR/PCBP4/TP53/AURKA/PML	16
BP	GO:0001941	postsynaptic membrane organization	7/2112	40/18670	0.1601	0.3369	0.2435	GLRB/ETV5/MAGI2/NLGN1/PTN/CDH2/DVL1	7
BP	GO:0009268	response to pH	7/2112	40/18670	0.1601	0.3369	0.2435	PAM/PCK1/HYAL1/CA2/GPR65/CLCN7/GPR4	7
BP	GO:0009395	phospholipid catabolic process	7/2112	40/18670	0.1601	0.3369	0.2435	PNPLA6/PLCG2/PLA2G4C/LIPG/PRDX6/ABHD6/LIPC	7
BP	GO:0042026	protein refolding	7/2112	40/18670	0.1601	0.3369	0.2435	HSPA6/NKTR/PPIC/PPIG/HSPA1L/BAG5/ST13	7
BP	GO:0042036	negative regulation of cytokine biosynthetic process	7/2112	40/18670	0.1601	0.3369	0.2435	PTPRC/INHBA/NMI/NFKB1/IL6/INPP5D/LILRB1	7
BP	GO:0071526	semaphorin-plexin signaling pathway	7/2112	40/18670	0.1601	0.3369	0.2435	SEMA4A/SEMA4D/SEMA3A/SEMA3F/SEMA4F/SEMA3E/SEMA6B	7
BP	GO:0072384	organelle transport along microtubule	13/2112	85/18670	0.1602	0.3369	0.2435	UCHL1/RASGRP1/MREG/TRAK2/KIF3B/DYNC1I1/FEZ1/TRIM58/MAP1B/SYBU/FYCO1/KIF1B/KIF23	13
BP	GO:0002313	mature B cell differentiation involved in immune response	4/2112	19/18670	0.1603	0.3369	0.2435	GPR183/DOCK10/ADA/PLCG2	4
BP	GO:0002363	alpha-beta T cell lineage commitment	4/2112	19/18670	0.1603	0.3369	0.2435	BATF/IRF4/TBX21/IL6	4
BP	GO:0002544	chronic inflammatory response	4/2112	19/18670	0.1603	0.3369	0.2435	CCL5/CXCL13/TNFAIP3/IDO1	4
BP	GO:0002689	negative regulation of leukocyte chemotaxis	4/2112	19/18670	0.1603	0.3369	0.2435	SLAMF8/GPR18/NBL1/CCL2	4
BP	GO:0002922	positive regulation of humoral immune response	4/2112	19/18670	0.1603	0.3369	0.2435	PTPRC/CCR7/IL1B/C6	4
BP	GO:0006337	nucleosome disassembly	4/2112	19/18670	0.1603	0.3369	0.2435	SMARCD3/SMARCC2/SMARCD1/HMGA1	4
BP	GO:0006534	cysteine metabolic process	4/2112	19/18670	0.1603	0.3369	0.2435	CDO1/CBS/AHCYL1/AHCYL2	4
BP	GO:0006555	methionine metabolic process	4/2112	19/18670	0.1603	0.3369	0.2435	BHMT2/AHCYL1/MAT1A/AHCYL2	4
BP	GO:0010523	negative regulation of calcium ion transport into cytosol	4/2112	19/18670	0.1603	0.3369	0.2435	SRI/PKD2/GSTO1/GSTM2	4
BP	GO:0015669	gas transport	4/2112	19/18670	0.1603	0.3369	0.2435	HBB/IPCEF1/CA2/HBD	4
BP	GO:0016048	detection of temperature stimulus	4/2112	19/18670	0.1603	0.3369	0.2435	CXCR4/EPHB1/HTR2A/LXN	4
BP	GO:0044241	lipid digestion	4/2112	19/18670	0.1603	0.3369	0.2435	CD36/AKR1C1/LEP/SOAT2	4
BP	GO:0045414	regulation of interleukin-8 biosynthetic process	4/2112	19/18670	0.1603	0.3369	0.2435	TLR8/CD74/CLEC7A/SYK	4
BP	GO:0046597	negative regulation of viral entry into host cell	4/2112	19/18670	0.1603	0.3369	0.2435	FCN1/TRIM26/GSN/PTX3	4
BP	GO:0051546	keratinocyte migration	4/2112	19/18670	0.1603	0.3369	0.2435	FGF7/MAPRE2/HBEGF/FERMT1	4
BP	GO:0060219	camera-type eye photoreceptor cell differentiation	4/2112	19/18670	0.1603	0.3369	0.2435	SOX9/PTN/DIO3/ROM1	4
BP	GO:0060231	mesenchymal to epithelial transition	4/2112	19/18670	0.1603	0.3369	0.2435	BMP4/STAT1/SIX2/FZD7	4
BP	GO:0071243	cellular response to arsenic-containing substance	4/2112	19/18670	0.1603	0.3369	0.2435	MAPK13/VCP/ZFAND1/GSTO1	4
BP	GO:0071800	podosome assembly	4/2112	19/18670	0.1603	0.3369	0.2435	LCP1/BIN2/HCK/GSN	4
BP	GO:0072087	renal vesicle development	4/2112	19/18670	0.1603	0.3369	0.2435	BMP4/STAT1/SOX9/SIX2	4
BP	GO:1900409	positive regulation of cellular response to oxidative stress	4/2112	19/18670	0.1603	0.3369	0.2435	SOD1/RGN/FOXO3/TLR6	4
BP	GO:1903798	regulation of production of miRNAs involved in gene silencing by miRNA	4/2112	19/18670	0.1603	0.3369	0.2435	BMP4/PPP3CA/EGFR/TP53	4
BP	GO:2000010	positive regulation of protein localization to cell surface	4/2112	19/18670	0.1603	0.3369	0.2435	CD247/HSP90AB1/STX4/GPD1L	4
BP	GO:2000831	regulation of steroid hormone secretion	4/2112	19/18670	0.1603	0.3369	0.2435	TAC1/PTPN11/AGTR1/REN	4
BP	GO:0001736	establishment of planar polarity	18/2112	124/18670	0.1609	0.3381	0.2443	PSMB9/SFRP1/PSMB8/PSMB10/PSME1/MAGI2/TP63/RYK/PLEKHA4/FZD4/FZD7/DACT1/GPC4/FZD6/DVL1/WDR1/FZD2/PFN1	18
BP	GO:0007164	establishment of tissue polarity	18/2112	124/18670	0.1609	0.3381	0.2443	PSMB9/SFRP1/PSMB8/PSMB10/PSME1/MAGI2/TP63/RYK/PLEKHA4/FZD4/FZD7/DACT1/GPC4/FZD6/DVL1/WDR1/FZD2/PFN1	18
BP	GO:0006888	ER to Golgi vesicle-mediated transport	29/2112	212/18670	0.1618	0.3398	0.2455	COPZ2/SERPINA1/GAS1/ANK2/COG5/CTSC/GOLGA2/DYNC1LI2/PROS1/F5/SEC31A/CREB3L2/RAB33B/DYNC1I1/YIPF5/KDELR3/VCP/STX18/ANKRD28/DCTN6/KDELR2/BCAP29/CAPZA1/GOLGB1/ERGIC2/VTI1B/CNIH1/SEC23B/SPTBN1	29
BP	GO:0030518	intracellular steroid hormone receptor signaling pathway	19/2112	132/18670	0.1619	0.3399	0.2456	SFRP1/RBFOX2/LMO3/AR/KANK2/JAK2/YAP1/TAF7/UFSP2/TP63/PMEPA1/ARNTL/PAK1/PARP1/CALCOCO1/RB1/RWDD1/NRIP1/RNF14	19
BP	GO:0006836	neurotransmitter transport	36/2112	269/18670	0.1624	0.3402	0.2458	PREPL/MCTP1/PRKCB/PFN2/HBB/SLC18A2/SLC29A1/SNCAIP/ADA/SLC1A3/SLC25A22/NLGN1/PER2/ARL6IP5/HTR2A/CHRNA5/KMO/ATP1A2/SYT17/PRAF2/STX4/SYK/VAMP2/STXBP1/BACE1/BTK/MAOB/SLC29A2/SNCG/LYN/NAAA/DVL1/CASK/P2RY4/LILRB1/CADPS	36
BP	GO:0009185	ribonucleoside diphosphate metabolic process	20/2112	140/18670	0.1626	0.3402	0.2458	AMPD3/IGF1/ZBTB20/SLC2A6/CBFA2T3/NUP93/HDAC4/HK3/ALDOC/TPR/NUP160/AK1/HTR2A/IFNG/ARNT/ENTPD4/NUP88/NUP50/TP53/CASK	20
BP	GO:0033865	nucleoside bisphosphate metabolic process	20/2112	140/18670	0.1626	0.3402	0.2458	ENPP1/KYNU/SLC26A2/PMVK/MPC2/ACAT1/ACACB/HSD17B12/SUCLA2/PDK4/TPST1/ELOVL4/MPC1/ELOVL2/AASS/ACSM5/ACSM3/ACSL5/BPNT1/ELOVL5	20
BP	GO:0033875	ribonucleoside bisphosphate metabolic process	20/2112	140/18670	0.1626	0.3402	0.2458	ENPP1/KYNU/SLC26A2/PMVK/MPC2/ACAT1/ACACB/HSD17B12/SUCLA2/PDK4/TPST1/ELOVL4/MPC1/ELOVL2/AASS/ACSM5/ACSM3/ACSL5/BPNT1/ELOVL5	20
BP	GO:0034032	purine nucleoside bisphosphate metabolic process	20/2112	140/18670	0.1626	0.3402	0.2458	ENPP1/KYNU/SLC26A2/PMVK/MPC2/ACAT1/ACACB/HSD17B12/SUCLA2/PDK4/TPST1/ELOVL4/MPC1/ELOVL2/AASS/ACSM5/ACSM3/ACSL5/BPNT1/ELOVL5	20
BP	GO:0006891	intra-Golgi vesicle-mediated transport	6/2112	33/18670	0.163	0.3402	0.2458	COPZ2/COG5/GABARAPL2/GOLGA3/RAB33B/VTI1B	6
BP	GO:0010039	response to iron ion	6/2112	33/18670	0.163	0.3402	0.2458	CYBRD1/CCNB1/TFAP2A/CCND1/HFE/ALAD	6
BP	GO:0010092	specification of animal organ identity	6/2112	33/18670	0.163	0.3402	0.2458	BMP4/GLI3/AR/SIX1/SMARCD3/HOXA11	6
BP	GO:0010591	regulation of lamellipodium assembly	6/2112	33/18670	0.163	0.3402	0.2458	RAC2/AUTS2/HDAC4/WAS/FER/WASF2	6
BP	GO:0016242	negative regulation of macroautophagy	6/2112	33/18670	0.163	0.3402	0.2458	NPC1/FEZ1/PIK3CA/PINK1/FEZ2/TP53	6
BP	GO:0032691	negative regulation of interleukin-1 beta production	6/2112	33/18670	0.163	0.3402	0.2458	TNFAIP3/IGF1/CX3CR1/SERPINB1/PML/NLRP3	6
BP	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	6/2112	33/18670	0.163	0.3402	0.2458	SRI/OXCT1/MPC2/STX4/SYBU/GPR27	6
BP	GO:0036314	response to sterol	6/2112	33/18670	0.163	0.3402	0.2458	CCR5/LRP6/INHBA/NFE2L1/PMVK/DAG1	6
BP	GO:0042339	keratan sulfate metabolic process	6/2112	33/18670	0.163	0.3402	0.2458	PRELP/FMOD/OGN/LUM/B3GNT2/B4GALT2	6
BP	GO:0045191	regulation of isotype switching	6/2112	33/18670	0.163	0.3402	0.2458	PTPRC/IL27RA/CD40/TFRC/TBX21/THOC1	6
BP	GO:0051443	positive regulation of ubiquitin-protein transferase activity	6/2112	33/18670	0.163	0.3402	0.2458	UBE2C/GOLGA2/PLK1/CDC14B/PINK1/CDC20	6
BP	GO:0051955	regulation of amino acid transport	6/2112	33/18670	0.163	0.3402	0.2458	PER2/ARL6IP5/LEP/KMO/ATP1A2/STXBP1	6
BP	GO:0006476	protein deacetylation	14/2112	93/18670	0.163	0.3402	0.2458	SKI/SIRT7/HDAC4/PRKD2/PER2/IFNG/MSL3/BEX4/NIPBL/PINK1/MORF4L1/PRKD1/TP53/TBL1X	14
BP	GO:0001756	somitogenesis	11/2112	70/18670	0.1632	0.3404	0.2459	SFRP1/LRP6/FOXC1/BMPR1A/COBL/MEOX1/LEF1/SMAD3/NOTCH1/NLE1/TP53	11
BP	GO:0002230	positive regulation of defense response to virus by host	5/2112	26/18670	0.1639	0.3404	0.2459	AIM2/STAT1/APOBEC3G/DDX58/LILRB1	5
BP	GO:0002360	T cell lineage commitment	5/2112	26/18670	0.1639	0.3404	0.2459	BATF/IRF4/TBX21/IL6/TP53	5
BP	GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin	5/2112	26/18670	0.1639	0.3404	0.2459	AGTR1/OR51E2/CPA3/CYBA/REN	5
BP	GO:0006779	porphyrin-containing compound biosynthetic process	5/2112	26/18670	0.1639	0.3404	0.2459	NFE2L1/SUCLA2/ALAS1/HMBS/ALAD	5
BP	GO:0034114	regulation of heterotypic cell-cell adhesion	5/2112	26/18670	0.1639	0.3404	0.2459	LCK/SKAP1/ADIPOQ/IL1RN/IL1B	5
BP	GO:0060074	synapse maturation	5/2112	26/18670	0.1639	0.3404	0.2459	CX3CR1/CLSTN1/SYBU/CDC20/PFN1	5
BP	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity	5/2112	26/18670	0.1639	0.3404	0.2459	SRI/PLN/PKD2/GSTO1/GSTM2	5
BP	GO:0060914	heart formation	5/2112	26/18670	0.1639	0.3404	0.2459	BMP4/PIM1/SIX1/BMPR1A/SMARCD3	5
BP	GO:0070911	global genome nucleotide-excision repair	5/2112	26/18670	0.1639	0.3404	0.2459	CETN2/PARP1/CUL4B/ERCC1/GTF2H5	5
BP	GO:0097066	response to thyroid hormone	5/2112	26/18670	0.1639	0.3404	0.2459	SIX1/CTSL/AKR1B1/CTSB/CTSH	5
BP	GO:1903203	regulation of oxidative stress-induced neuron death	5/2112	26/18670	0.1639	0.3404	0.2459	OXR1/LANCL1/PARP1/PINK1/TLR6	5
BP	GO:1903579	negative regulation of ATP metabolic process	5/2112	26/18670	0.1639	0.3404	0.2459	PID1/CBFA2T3/HDAC4/PARP1/TP53	5
BP	GO:0010823	negative regulation of mitochondrion organization	9/2112	55/18670	0.164	0.3404	0.2459	IGF1/CLU/TMEM14A/HGF/HIGD1A/PINK1/LMNA/SLC25A5/TP53	9
BP	GO:0046456	icosanoid biosynthetic process	9/2112	55/18670	0.164	0.3404	0.2459	LTC4S/AKR1C3/CD74/HPGDS/SYK/FABP5/PTGS1/IL1B/ALOX5	9
BP	GO:0097120	receptor localization to synapse	9/2112	55/18670	0.164	0.3404	0.2459	RAB8A/DAG1/NLGN1/CLSTN1/ADAM22/GPC4/LGI1/ADAM10/CEP112	9
BP	GO:0046545	development of primary female sexual characteristics	15/2112	101/18670	0.1653	0.3428	0.2477	KITLG/PLEKHA1/SFRP1/FOXC1/INHBA/ZFPM2/SGPL1/ICAM1/SOD1/FZD4/LEP/FOXO3/ANG/NRIP1/PTX3	15
BP	GO:0097006	regulation of plasma lipoprotein particle levels	15/2112	101/18670	0.1653	0.3428	0.2477	CSK/LPCAT3/ABCG1/CD36/NPC1/LRPAP1/LIPG/MYLIP/AGTR1/ADIPOQ/CETP/HDLBP/LIPC/PLA2G7/SOAT2	15
BP	GO:0001676	long-chain fatty acid metabolic process	16/2112	109/18670	0.167	0.3461	0.2501	LTC4S/PLP1/AKR1C3/PAM/HPGDS/PLA2G4C/GPX4/PTGS1/SLC27A5/ACADL/ELOVL2/GSTM2/ACSL5/EPHX2/ALOX5/ELOVL5	16
BP	GO:0000271	polysaccharide biosynthetic process	12/2112	78/18670	0.1673	0.3461	0.2501	ENPP1/IGF1/PPP1R3C/EXTL2/PASK/PER2/NFKB1/PPP1CA/SORBS1/EXT2/B3GNT2/UGP2	12
BP	GO:0010827	regulation of glucose transmembrane transport	12/2112	78/18670	0.1673	0.3461	0.2501	ENPP1/PID1/PIK3R1/IGF1/PRKCB/PTPN11/LEP/ADIPOQ/FABP5/SORBS1/CLIP3/IL1B	12
BP	GO:0014743	regulation of muscle hypertrophy	12/2112	78/18670	0.1673	0.3461	0.2501	IGFBP5/IGF1/TNFRSF1B/PPP3CA/FOXO1/SMAD3/NOTCH1/IL6ST/PAK1/PARP1/JARID2/LMNA	12
BP	GO:0021954	central nervous system neuron development	12/2112	78/18670	0.1673	0.3461	0.2501	NTRK2/TSKU/SEMA3A/GATA2/NFIB/EPHB1/TCTN1/SCN1B/LEP/HSP90AB1/FEZF2/DCLK1	12
BP	GO:0033143	regulation of intracellular steroid hormone receptor signaling pathway	12/2112	78/18670	0.1673	0.3461	0.2501	SFRP1/LMO3/AR/KANK2/YAP1/UFSP2/TP63/ARNTL/PAK1/PARP1/RWDD1/RNF14	12
BP	GO:0061333	renal tubule morphogenesis	12/2112	78/18670	0.1673	0.3461	0.2501	BMP4/SOX9/GLI3/SIX1/SIX2/FGF2/PBX1/DCHS1/FAT4/PKD2/HOXA11/AHI1	12
BP	GO:0051153	regulation of striated muscle cell differentiation	17/2112	117/18670	0.1683	0.3482	0.2516	CXCL9/BMP4/IGF1/IL4R/HDAC4/SHOX2/CXCL10/SIK1/EZH2/CD53/CEACAM5/BHLHE41/FZD7/NOTCH1/PAK1/AKAP13/CFLAR	17
BP	GO:0010466	negative regulation of peptidase activity	35/2112	262/18670	0.1691	0.3496	0.2526	LAMP3/SERPINA1/TNFAIP8/BIRC3/TIMP3/SPOCK2/CST7/SERPINA3/SERPINA5/SLPI/PTTG1/SPOCK1/TIMP4/CRYAB/TIMP2/RPS6KA1/RECK/PROS1/CR1/UBE2Z/SPINT2/ITIH5/HGF/CD27/PEBP1/LEF1/SERPINI1/MICAL1/LXN/SERPINB1/APLP2/TFPI/NLE1/CFLAR/SPINK5	35
BP	GO:0009749	response to glucose	27/2112	197/18670	0.1694	0.3501	0.253	ZBTB20/SRI/OXCT1/PPP3CA/ICAM1/KLF7/MPC2/TCF7L2/PCK1/LRP5/NOX4/RMI1/EFNA5/PIK3CA/SLC8A1/ADIPOQ/STX4/VAMP2/NDUFA9/SYBU/FOXO3/ENSA/CYBA/RAB11FIP2/ZNF236/GPR27/TXN2	27
BP	GO:0008089	anterograde axonal transport	8/2112	48/18670	0.1699	0.3509	0.2535	TRAK2/KIF3B/KIF4A/SOD1/FEZ1/HSPB1/SYBU/KIF1B	8
BP	GO:0061647	histone H3-K9 modification	8/2112	48/18670	0.1699	0.3509	0.2535	NAP1L2/KMT2A/DNMT1/ATRX/PAX5/MECP2/JARID2/LMNA	8
BP	GO:0071333	cellular response to glucose stimulus	19/2112	133/18670	0.17	0.3511	0.2537	ZBTB20/SRI/OXCT1/PPP3CA/ICAM1/KLF7/MPC2/PCK1/LRP5/NOX4/EFNA5/PIK3CA/STX4/SYBU/FOXO3/CYBA/RAB11FIP2/ZNF236/GPR27	19
BP	GO:0035418	protein localization to synapse	10/2112	63/18670	0.1701	0.3511	0.2537	RAB8A/DAG1/NLGN1/CLSTN1/ADAM22/GPC4/HSPB1/LGI1/ADAM10/DVL1	10
BP	GO:0001738	morphogenesis of a polarized epithelium	20/2112	141/18670	0.1705	0.3519	0.2542	PSMB9/SFRP1/PSMB8/DLG5/PSMB10/PSME1/MAGI2/TP63/RYK/PLEKHA4/FZD4/FZD7/DACT1/GPC4/FZD6/DVL1/WDR1/FZD2/PFN1/AHI1	20
BP	GO:0016525	negative regulation of angiogenesis	24/2112	173/18670	0.1706	0.3519	0.2543	CCR2/SEMA4A/STAT1/FOXC1/ITGB1BP1/SULF1/HLA-G/CXCL10/THBS4/DCN/CD160/CX3CR1/PTN/TNMD/PLK2/NOTCH1/MECP2/PRL/SEMA3E/PDE3B/SPINK5/GPR4/HOXA5/PML	24
BP	GO:0014074	response to purine-containing compound	21/2112	149/18670	0.1708	0.3522	0.2545	IGFBP5/CDO1/PENK/STAT1/AQP9/NDUFS4/PCK1/NOX4/SOD1/ZFP36L1/SLC8A1/ADIPOQ/P2RY6/FOSL1/RYR3/PANX1/PKD2/REN/GSTM2/IL1B/P2RY4	21
BP	GO:1905952	regulation of lipid localization	22/2112	157/18670	0.1709	0.3522	0.2545	FTO/ABCG1/PTPN2/CD36/ATP8A1/TAC1/NFKBIA/ACACB/NFKB1/PTPN11/LIPG/LEP/AGTR1/ADIPOQ/SYK/CETP/MEST/IL6/NR1H3/REN/ITGAV/IL1B	22
BP	GO:0009165	nucleotide biosynthetic process	50/2112	386/18670	0.1711	0.3526	0.2547	PID1/AMPD3/IGF1/IDO1/ZBTB20/KYNU/UPP1/ADK/SLC2A6/NPR2/CBFA2T3/SLC26A2/RRM2/NUP93/HDAC4/HK3/NME7/ADA/ALDOC/MPC2/IDH2/TPR/ACAT1/NUP160/ACACB/AK1/HTR2A/HSD17B12/VCP/IFNG/ARNT/KMO/PNP/PDK4/PARP1/PINK1/ELOVL4/TYMS/MPC1/GUCA1A/NME4/NUP88/ELOVL2/TK2/NUP50/TP53/ACSL5/AK6/ELOVL5/PRPS2	50
BP	GO:0044728	DNA methylation or demethylation	14/2112	94/18670	0.1729	0.3561	0.2573	FTO/APOBEC3G/APOBEC3B/KMT2A/EZH2/DNMT1/ATRX/PIK3CA/MECP2/MPHOSPH8/RLF/PARP1/SPI1/USP7	14
BP	GO:0060993	kidney morphogenesis	14/2112	94/18670	0.1729	0.3561	0.2573	BMP4/STAT1/SOX9/GLI3/SIX1/SIX2/FGF2/PBX1/DCHS1/WWTR1/FAT4/PKD2/HOXA11/AHI1	14
BP	GO:1901605	alpha-amino acid metabolic process	30/2112	222/18670	0.1738	0.3563	0.2574	BHMT2/FAH/CDO1/IDO1/ALDH7A1/SERINC3/KYNU/ALDH6A1/CBS/PCBD1/OAT/DDAH2/SLC1A3/MCCC1/ASPA/CRTAP/AHCYL1/ACAT1/NOX4/HPD/MAT1A/GFPT1/P4HTM/PSPH/KMO/MECP2/AHCYL2/AASS/GFPT2/ALDH5A1	30
BP	GO:0015893	drug transport	29/2112	214/18670	0.1746	0.3563	0.2574	SLC47A1/INHBA/HBB/NFKBIE/SLC18A2/SLC1A3/TAF7/SLC25A22/PER2/ARL6IP5/SLC7A5/FZD4/HTR2A/IPCEF1/PTPN11/CA2/HBD/SLC25A4/ATP1A2/SYT17/PRAF2/SLC25A23/PINK1/SNCG/CD320/RALBP1/SLC25A5/LMBRD1/SLC5A6	29
BP	GO:0033692	cellular polysaccharide biosynthetic process	11/2112	71/18670	0.1747	0.3563	0.2574	ENPP1/IGF1/PPP1R3C/EXTL2/PASK/PER2/PPP1CA/SORBS1/EXT2/B3GNT2/UGP2	11
BP	GO:0001845	phagolysosome assembly	3/2112	13/18670	0.1752	0.3563	0.2574	CORO1A/RAB20/RAB14	3
BP	GO:0001886	endothelial cell morphogenesis	3/2112	13/18670	0.1752	0.3563	0.2574	ARHGEF26/TNMD/PECAM1	3
BP	GO:0002281	macrophage activation involved in immune response	3/2112	13/18670	0.1752	0.3563	0.2574	DYSF/SYK/SBNO2	3
BP	GO:0002679	respiratory burst involved in defense response	3/2112	13/18670	0.1752	0.3563	0.2574	SLAMF8/PIK3CD/HCK	3
BP	GO:0002829	negative regulation of type 2 immune response	3/2112	13/18670	0.1752	0.3563	0.2574	CCR2/IL27RA/TBX21	3
BP	GO:0002864	regulation of acute inflammatory response to antigenic stimulus	3/2112	13/18670	0.1752	0.3563	0.2574	CCR7/HLA-E/BTK	3
BP	GO:0009162	deoxyribonucleoside monophosphate metabolic process	3/2112	13/18670	0.1752	0.3563	0.2574	TYMS/TK2/TK1	3
BP	GO:0010459	negative regulation of heart rate	3/2112	13/18670	0.1752	0.3563	0.2574	SRI/TAC1/PLN	3
BP	GO:0021520	spinal cord motor neuron cell fate specification	3/2112	13/18670	0.1752	0.3563	0.2574	HOXC10/GLI3/HOXD10	3
BP	GO:0030007	cellular potassium ion homeostasis	3/2112	13/18670	0.1752	0.3563	0.2574	KCNJ2/ATP1B1/ATP1A2	3
BP	GO:0030497	fatty acid elongation	3/2112	13/18670	0.1752	0.3563	0.2574	ELOVL4/ELOVL2/ELOVL5	3
BP	GO:0031115	negative regulation of microtubule polymerization	3/2112	13/18670	0.1752	0.3563	0.2574	TUBB4A/CLIP3/CDH5	3
BP	GO:0031274	positive regulation of pseudopodium assembly	3/2112	13/18670	0.1752	0.3563	0.2574	CCR7/CCL21/CDC42EP3	3
BP	GO:0033004	negative regulation of mast cell activation	3/2112	13/18670	0.1752	0.3563	0.2574	LGALS9/IL13RA2/FER	3
BP	GO:0042538	hyperosmotic salinity response	3/2112	13/18670	0.1752	0.3563	0.2574	AKR1B1/MICU1/SLC25A23	3
BP	GO:0042761	very long-chain fatty acid biosynthetic process	3/2112	13/18670	0.1752	0.3563	0.2574	ELOVL4/ELOVL2/ELOVL5	3
BP	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway	3/2112	13/18670	0.1752	0.3563	0.2574	IGFBP5/IGF1/AR	3
BP	GO:0046349	amino sugar biosynthetic process	3/2112	13/18670	0.1752	0.3563	0.2574	NAGK/GFPT1/GFPT2	3
BP	GO:0046831	regulation of RNA export from nucleus	3/2112	13/18670	0.1752	0.3563	0.2574	CPSF6/TPR/KHDRBS1	3
BP	GO:0048505	regulation of timing of cell differentiation	3/2112	13/18670	0.1752	0.3563	0.2574	NOTCH1/FGF9/GDPD5	3
BP	GO:0050746	regulation of lipoprotein metabolic process	3/2112	13/18670	0.1752	0.3563	0.2574	LIPG/LEP/ITGAV	3
BP	GO:0050872	white fat cell differentiation	3/2112	13/18670	0.1752	0.3563	0.2574	PER2/FABP4/CEBPA	3
BP	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain	3/2112	13/18670	0.1752	0.3563	0.2574	CXCR4/HTR2A/BACE1	3
BP	GO:0060100	positive regulation of phagocytosis, engulfment	3/2112	13/18670	0.1752	0.3563	0.2574	CD36/GATA2/NCKAP1L	3
BP	GO:0060576	intestinal epithelial cell development	3/2112	13/18670	0.1752	0.3563	0.2574	YIPF6/TYMS/HOXA5	3
BP	GO:0061000	negative regulation of dendritic spine development	3/2112	13/18670	0.1752	0.3563	0.2574	NLGN1/PTPRS/PLK2	3
BP	GO:0061029	eyelid development in camera-type eye	3/2112	13/18670	0.1752	0.3563	0.2574	INHBA/EGFR/TFAP2A	3
BP	GO:0061042	vascular wound healing	3/2112	13/18670	0.1752	0.3563	0.2574	NDNF/TNFAIP3/CXCR4	3
BP	GO:0061430	bone trabecula morphogenesis	3/2112	13/18670	0.1752	0.3563	0.2574	SFRP1/SEMA4D/SBNO2	3
BP	GO:0090179	planar cell polarity pathway involved in neural tube closure	3/2112	13/18670	0.1752	0.3563	0.2574	SFRP1/DVL1/FZD2	3
BP	GO:0090713	immunological memory process	3/2112	13/18670	0.1752	0.3563	0.2574	TNFRSF14/CD160/CD81	3
BP	GO:0097152	mesenchymal cell apoptotic process	3/2112	13/18670	0.1752	0.3563	0.2574	GDF5/SOX9/ETV6	3
BP	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response	3/2112	13/18670	0.1752	0.3563	0.2574	PIK3R1/PTPN2/BAK1	3
BP	GO:1902430	negative regulation of amyloid-beta formation	3/2112	13/18670	0.1752	0.3563	0.2574	IGF1/CLU/SPON1	3
BP	GO:1902902	negative regulation of autophagosome assembly	3/2112	13/18670	0.1752	0.3563	0.2574	FEZ1/PINK1/FEZ2	3
BP	GO:1905155	positive regulation of membrane invagination	3/2112	13/18670	0.1752	0.3563	0.2574	CD36/GATA2/NCKAP1L	3
BP	GO:0030835	negative regulation of actin filament depolymerization	7/2112	41/18670	0.1754	0.3564	0.2575	ADD3/TMOD1/LMOD1/CAPZA1/VILL/SPTBN1/GSN	7
BP	GO:0048286	lung alveolus development	7/2112	41/18670	0.1754	0.3564	0.2575	BMP4/IGFBP5/LTBP3/ADA/TNS3/TGFB3/HOXA5	7
BP	GO:0070317	negative regulation of G0 to G1 transition	7/2112	41/18670	0.1754	0.3564	0.2575	TFDP2/RRM2/HLA-G/EZH2/CDC7/SUZ12/APAF1	7
BP	GO:0006664	glycolipid metabolic process	16/2112	110/18670	0.1762	0.3575	0.2583	PIGK/STS/B3GALNT1/DPM3/GPAA1/GAL3ST4/FA2H/PIGH/FUCA1/PIGP/GLA/PIGT/PIGF/UGCG/CERK/ALDH5A1	16
BP	GO:0006939	smooth muscle contraction	16/2112	110/18670	0.1762	0.3575	0.2583	PLCE1/SULF1/COMP/HTR2B/ADA/SPHK1/SOD1/HTR2A/ATP1A2/SLC8A1/EDNRB/CTTN/CD38/PRKG1/MYH11/MYLK	16
BP	GO:0090175	regulation of establishment of planar polarity	16/2112	110/18670	0.1762	0.3575	0.2583	PSMB9/SFRP1/PSMB8/PSMB10/PSME1/MAGI2/RYK/PLEKHA4/FZD4/FZD7/DACT1/GPC4/FZD6/DVL1/FZD2/PFN1	16
BP	GO:0022029	telencephalon cell migration	9/2112	56/18670	0.1771	0.3592	0.2596	CXCR4/GLI3/SEMA3A/EGFR/FGF13/DIXDC1/POU3F3/FEZF2/MBOAT7	9
BP	GO:0046031	ADP metabolic process	18/2112	126/18670	0.1779	0.3608	0.2607	AMPD3/IGF1/ZBTB20/SLC2A6/CBFA2T3/NUP93/HDAC4/HK3/ALDOC/TPR/NUP160/AK1/HTR2A/IFNG/ARNT/NUP88/NUP50/TP53	18
BP	GO:0043536	positive regulation of blood vessel endothelial cell migration	12/2112	79/18670	0.1783	0.3611	0.2609	FGF18/ANGPT1/CD40/PRKD2/GATA2/FGF2/SP1/PLK2/HSPB1/AKT3/PRKD1/KDR	12
BP	GO:0009152	purine ribonucleotide biosynthetic process	37/2112	280/18670	0.1783	0.3611	0.2609	PID1/AMPD3/IGF1/ZBTB20/ADK/SLC2A6/NPR2/CBFA2T3/SLC26A2/NUP93/HDAC4/HK3/NME7/ALDOC/MPC2/TPR/ACAT1/NUP160/ACACB/AK1/HTR2A/HSD17B12/VCP/IFNG/ARNT/PDK4/PARP1/PINK1/ELOVL4/MPC1/NME4/NUP88/ELOVL2/NUP50/TP53/ACSL5/ELOVL5	37
BP	GO:0002920	regulation of humoral immune response	19/2112	134/18670	0.1784	0.3611	0.2609	CXCL13/PTPRC/CLU/CCR7/CFP/PTPN6/PROS1/CR1/CD19/IGLC1/IGLV1-44/C7/IGHG1/CFB/CD81/SPINK5/IL1B/CR2/C6	19
BP	GO:0006165	nucleoside diphosphate phosphorylation	19/2112	134/18670	0.1784	0.3611	0.2609	IGF1/ZBTB20/SLC2A6/CBFA2T3/NUP93/HDAC4/HK3/NME7/ALDOC/TPR/NUP160/AK1/HTR2A/IFNG/ARNT/NME4/NUP88/NUP50/TP53	19
BP	GO:0006914	autophagy	63/2112	496/18670	0.1784	0.3611	0.2609	LAMP3/S100A9/UCHL1/CLU/GABARAPL1/IRF8/RAB8A/TBC1D5/TCIRG1/RASIP1/GOLGA2/PIP4K2B/HTR2B/RIPK2/GABARAPL2/DAP/DCN/NPC1/HGF/MTMR14/RAB33B/VPS16/SNX5/TRIM21/FOXO1/VPS37C/PLK2/FBXL2/FEZ1/VCP/LEP/IFNG/PIK3CA/FNBP1L/ATG3/IL10RA/IKBKG/HSPB1/TRIM22/CTTN/PINK1/PTPN22/CHMP2B/DDIT3/PIP4K2A/FOXO3/GFAP/PRKD1/SESN1/NOD1/EPM2A/EMC6/KDR/FEZ2/FYCO1/WAC/USP10/TP53/BNIP3L/PRKAB1/ATP6V1B2/PIM2/DRAM1	63
BP	GO:0061919	process utilizing autophagic mechanism	63/2112	496/18670	0.1784	0.3611	0.2609	LAMP3/S100A9/UCHL1/CLU/GABARAPL1/IRF8/RAB8A/TBC1D5/TCIRG1/RASIP1/GOLGA2/PIP4K2B/HTR2B/RIPK2/GABARAPL2/DAP/DCN/NPC1/HGF/MTMR14/RAB33B/VPS16/SNX5/TRIM21/FOXO1/VPS37C/PLK2/FBXL2/FEZ1/VCP/LEP/IFNG/PIK3CA/FNBP1L/ATG3/IL10RA/IKBKG/HSPB1/TRIM22/CTTN/PINK1/PTPN22/CHMP2B/DDIT3/PIP4K2A/FOXO3/GFAP/PRKD1/SESN1/NOD1/EPM2A/EMC6/KDR/FEZ2/FYCO1/WAC/USP10/TP53/BNIP3L/PRKAB1/ATP6V1B2/PIM2/DRAM1	63
BP	GO:0009132	nucleoside diphosphate metabolic process	22/2112	158/18670	0.1785	0.3612	0.261	AMPD3/IGF1/ZBTB20/SLC2A6/CBFA2T3/NUP93/HDAC4/HK3/NME7/ALDOC/TPR/NUP160/AK1/HTR2A/IFNG/ARNT/ENTPD4/NME4/NUP88/NUP50/TP53/CASK	22
BP	GO:0046467	membrane lipid biosynthetic process	20/2112	142/18670	0.1786	0.3613	0.261	PIGK/ALDH3A2/SGPL1/PRKD2/SPHK1/DPM3/GPAA1/GAL3ST4/FA2H/PIGH/PIGP/SGMS1/ELOVL4/PRKD1/PIGT/ELOVL2/PIGF/UGCG/ELOVL5/CERS4	20
BP	GO:0003382	epithelial cell morphogenesis	6/2112	34/18670	0.1803	0.3638	0.2629	BCL11B/AR/ARHGEF26/SPINT2/TNMD/PECAM1	6
BP	GO:0010765	positive regulation of sodium ion transport	6/2112	34/18670	0.1803	0.3638	0.2629	FXYD1/AHCYL1/ATP1B1/SCN1B/TESC/GPD1L	6
BP	GO:0021522	spinal cord motor neuron differentiation	6/2112	34/18670	0.1803	0.3638	0.2629	HOXC10/GLI3/NFE2L1/TCTN1/HOXD10/GDPD5	6
BP	GO:0031128	developmental induction	6/2112	34/18670	0.1803	0.3638	0.2629	BMP4/SOX9/AR/SIX1/HIPK2/HOXA11	6
BP	GO:0034205	amyloid-beta formation	6/2112	34/18670	0.1803	0.3638	0.2629	IGF1/CLU/ABCG1/SPON1/IFNG/ADAM10	6
BP	GO:0045920	negative regulation of exocytosis	6/2112	34/18670	0.1803	0.3638	0.2629	CCR2/HLA-F/LGALS9/IL13RA2/RAB33B/NOTCH1	6
BP	GO:0097009	energy homeostasis	6/2112	34/18670	0.1803	0.3638	0.2629	AMPD3/CD36/PASK/ACACB/FOXO1/PIK3CA	6
BP	GO:0035773	insulin secretion involved in cellular response to glucose stimulus	10/2112	64/18670	0.1825	0.3668	0.265	SRI/OXCT1/KLF7/MPC2/LRP5/EFNA5/STX4/SYBU/RAB11FIP2/GPR27	10
BP	GO:0046782	regulation of viral transcription	10/2112	64/18670	0.1825	0.3668	0.265	CCL5/NUCKS1/CHD1/CCNT1/SP1/LEF1/TRIM21/GTF2F1/POLR2L/RSF1	10
BP	GO:0097193	intrinsic apoptotic signaling pathway	38/2112	289/18670	0.1828	0.3668	0.265	LCK/PIK3R1/S100A9/CLU/TNFRSF1B/BCL2A1/SERINC3/CD74/BID/PTPN2/ACKR3/JAK2/CDIP1/MELK/BAK1/TP63/NDUFA13/SOD1/BCL2L2/ARL6IP5/PMAIP1/PPM1F/PARP1/HSPB1/PINK1/APAF1/SGMS1/CUL2/IVNS1ABP/DDIT3/HIPK2/TP53BP2/BAG5/HINT1/CASP4/TP53/MOAP1/PML	38
BP	GO:0006302	double-strand break repair	33/2112	248/18670	0.1833	0.3668	0.265	NUCKS1/ZNF365/CDC45/BLM/BARD1/WAS/MCM5/REV3L/PPP4C/RNF138/FEN1/RMI1/TDP1/VCP/TIMELESS/CDC7/MCM2/DDX1/PARP1/ACTR8/NIPBL/REC8/MORF4L1/MCM4/RAD51AP1/ERCC1/SETMAR/SMCHD1/TRIP13/TP53/KDM2A/ACTR2/PML	33
BP	GO:0006071	glycerol metabolic process	4/2112	20/18670	0.1835	0.3668	0.265	GK/DYSF/PCK1/LEP	4
BP	GO:0006677	glycosylceramide metabolic process	4/2112	20/18670	0.1835	0.3668	0.265	FA2H/GLA/UGCG/ALDH5A1	4
BP	GO:0007095	mitotic G2 DNA damage checkpoint	4/2112	20/18670	0.1835	0.3668	0.265	BLM/CDK1/DONSON/SYF2	4
BP	GO:0010592	positive regulation of lamellipodium assembly	4/2112	20/18670	0.1835	0.3668	0.265	RAC2/AUTS2/HDAC4/WASF2	4
BP	GO:0030220	platelet formation	4/2112	20/18670	0.1835	0.3668	0.265	PTPN6/PTPN11/WDR1/NBEAL2	4
BP	GO:0031061	negative regulation of histone methylation	4/2112	20/18670	0.1835	0.3668	0.265	DNMT1/PAX5/MTF2/JARID2	4
BP	GO:0032462	regulation of protein homooligomerization	4/2112	20/18670	0.1835	0.3668	0.265	CLU/BID/CRYAB/CRBN	4
BP	GO:0043369	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment	4/2112	20/18670	0.1835	0.3668	0.265	BATF/IRF4/TBX21/IL6	4
BP	GO:0043586	tongue development	4/2112	20/18670	0.1835	0.3668	0.265	GLI3/SIX1/EGFR/LEF1	4
BP	GO:0045655	regulation of monocyte differentiation	4/2112	20/18670	0.1835	0.3668	0.265	CD74/IRF7/ZFP36L1/INPP5D	4
BP	GO:0048670	regulation of collateral sprouting	4/2112	20/18670	0.1835	0.3668	0.265	SEMA4D/FGF13/PTPRS/EFNA5	4
BP	GO:0060602	branch elongation of an epithelium	4/2112	20/18670	0.1835	0.3668	0.265	BMP4/SOX9/SIX1/YAP1	4
BP	GO:0071397	cellular response to cholesterol	4/2112	20/18670	0.1835	0.3668	0.265	LRP6/INHBA/NFE2L1/DAG1	4
BP	GO:1901881	positive regulation of protein depolymerization	4/2112	20/18670	0.1835	0.3668	0.265	PLEK/DSTN/CFL1/WDR1	4
BP	GO:0000188	inactivation of MAPK activity	5/2112	27/18670	0.1836	0.3668	0.265	PPP2CA/DUSP5/MBIP/DUSP6/DUSP2	5
BP	GO:0001964	startle response	5/2112	27/18670	0.1836	0.3668	0.265	PENK/GLRB/MECP2/BACE1/DVL1	5
BP	GO:0006730	one-carbon metabolic process	5/2112	27/18670	0.1836	0.3668	0.265	MTHFD2/AHCYL1/MAT1A/AHCYL2/TYMS	5
BP	GO:0015721	bile acid and bile salt transport	5/2112	27/18670	0.1836	0.3668	0.265	AQP9/AKR1C1/STARD5/SLC27A5/SLCO1C1	5
BP	GO:0035902	response to immobilization stress	5/2112	27/18670	0.1836	0.3668	0.265	SLC8A1/FOXO3/REN/ERCC1/ACTR2	5
BP	GO:0036475	neuron death in response to oxidative stress	5/2112	27/18670	0.1836	0.3668	0.265	OXR1/LANCL1/PARP1/PINK1/TLR6	5
BP	GO:0043032	positive regulation of macrophage activation	5/2112	27/18670	0.1836	0.3668	0.265	IL4R/TNIP2/CTSC/CEBPA/TLR6	5
BP	GO:0048143	astrocyte activation	5/2112	27/18670	0.1836	0.3668	0.265	EGFR/IFNG/IL6/FPR2/IL1B	5
BP	GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization	5/2112	27/18670	0.1836	0.3668	0.265	CACNA2D1/ANK2/SCN1B/WDR1/SNTA1	5
BP	GO:0071514	genetic imprinting	5/2112	27/18670	0.1836	0.3668	0.265	CDKN1C/NDN/DIRAS3/PIK3CA/MECP2	5
BP	GO:0090169	regulation of spindle assembly	5/2112	27/18670	0.1836	0.3668	0.265	PLK1/TPR/STAG2/CHMP2B/CHMP1B	5
BP	GO:0098810	neurotransmitter reuptake	5/2112	27/18670	0.1836	0.3668	0.265	SLC18A2/SLC29A1/PER2/ATP1A2/SLC29A2	5
BP	GO:1902175	regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	5/2112	27/18670	0.1836	0.3668	0.265	SOD1/PARP1/HSPB1/PINK1/BAG5	5
BP	GO:0051604	protein maturation	51/2112	397/18670	0.1842	0.3676	0.2656	GAS1/YME1L1/BIRC3/CLU/CST7/GLI3/XPNPEP3/ADAM8/CFP/COMP/CPD/RIPK2/SRGN/PROS1/CREBBP/SPON1/CR1/BAG2/BAK1/GLG1/ASPH/PLAT/AFG3L2/CASP1/CD19/CPE/CYFIP2/IGLC1/IGLV1-44/C7/NFU1/CPA3/PARP1/TSPAN14/IGHG1/TASP1/TESC/ADAM10/SEC11A/METAP2/CFB/CD81/LIPT1/REN/RFX4/GSN/IL1B/CR2/C6/CTSH/PCSK7	51
BP	GO:0030857	negative regulation of epithelial cell differentiation	8/2112	49/18670	0.1843	0.3676	0.2656	STAT1/SOX9/YAP1/EZH2/TP63/NOTCH1/IFNG/CCND1	8
BP	GO:0071825	protein-lipid complex subunit organization	8/2112	49/18670	0.1843	0.3676	0.2656	ABCG1/PCDHGA3/LIPG/AGTR1/CETP/LIPC/PLA2G7/SOAT2	8
BP	GO:1990090	cellular response to nerve growth factor stimulus	8/2112	49/18670	0.1843	0.3676	0.2656	CORO1A/MICALL1/NTRK2/DYNC1LI2/TAC1/MAGI2/FOXO3/KIF1B	8
BP	GO:0044264	cellular polysaccharide metabolic process	15/2112	103/18670	0.1845	0.368	0.2659	ENPP1/IGF1/PPP1R3C/EXTL2/PASK/PHKB/PER2/IL6ST/PPP1CA/SORBS1/AOAH/EXT2/B3GNT2/UGP2/MANBA	15
BP	GO:2000181	negative regulation of blood vessel morphogenesis	24/2112	175/18670	0.1853	0.3695	0.267	CCR2/SEMA4A/STAT1/FOXC1/ITGB1BP1/SULF1/HLA-G/CXCL10/THBS4/DCN/CD160/CX3CR1/PTN/TNMD/PLK2/NOTCH1/MECP2/PRL/SEMA3E/PDE3B/SPINK5/GPR4/HOXA5/PML	24
BP	GO:0098661	inorganic anion transmembrane transport	16/2112	111/18670	0.1856	0.37	0.2673	ANKH/APOL1/PCYOX1/GLRB/FXYD1/SLC26A2/CLCN4/SLC1A3/SLC37A1/SLC12A2/SLC12A8/CLIC5/SLC12A7/CLCN7/CLCN5/CLCC1	16
BP	GO:0061982	meiosis I cell cycle process	17/2112	119/18670	0.1863	0.3713	0.2683	PTTG1/PTTG3P/PLK1/UBE2B/CDC25B/TOP2A/MYBL1/RMI1/CKS2/STAG3/TERF1/FBXO5/REC8/ERCC1/TRIP13/CCNE2/AURKA	17
BP	GO:0032024	positive regulation of insulin secretion	11/2112	72/18670	0.1865	0.3714	0.2684	SRI/OXCT1/JAK2/TM7SF3/MPC2/TCF7L2/RBP4/STX4/CD38/SYBU/GPR27	11
BP	GO:1903747	regulation of establishment of protein localization to mitochondrion	11/2112	72/18670	0.1865	0.3714	0.2684	TFDP2/RAC2/GZMB/BID/TP63/PMAIP1/PINK1/HSPA1L/TP53BP2/TP53/BNIP3L	11
BP	GO:0035270	endocrine system development	18/2112	127/18670	0.1868	0.3716	0.2685	BMP4/CDKN1C/SOX9/SIX1/BMPR1A/GATA2/BAK1/SOX2/PITX1/PBX1/FOXO1/SMAD3/ARNTL/IL6/FSTL3/DKK3/HOXA5/THRA	18
BP	GO:0035296	regulation of tube diameter	20/2112	143/18670	0.1869	0.3716	0.2685	GCH1/FOXC1/ITGB1BP1/HBB/ICAM1/COMP/HTR2B/EGFR/PER2/SOD1/HTR2A/HRH1/LEP/AGTR1/ATP1A2/SLC8A1/EDNRB/CD38/PRKG1/EPHX2	20
BP	GO:0048813	dendrite morphogenesis	20/2112	143/18670	0.1869	0.3716	0.2685	RBFOX2/SEMA4D/DOCK10/SEMA3A/PPP3CA/ZNF365/PTPRD/TRAK2/WASL/KLF7/NLGN1/EPHB1/PTN/PDLIM5/CFL1/ADAM10/DVL1/ABI2/ACTR2/DCLK1	20
BP	GO:0050880	regulation of blood vessel size	20/2112	143/18670	0.1869	0.3716	0.2685	GCH1/FOXC1/ITGB1BP1/HBB/ICAM1/COMP/HTR2B/EGFR/PER2/SOD1/HTR2A/HRH1/LEP/AGTR1/ATP1A2/SLC8A1/EDNRB/CD38/PRKG1/EPHX2	20
BP	GO:0097746	regulation of blood vessel diameter	20/2112	143/18670	0.1869	0.3716	0.2685	GCH1/FOXC1/ITGB1BP1/HBB/ICAM1/COMP/HTR2B/EGFR/PER2/SOD1/HTR2A/HRH1/LEP/AGTR1/ATP1A2/SLC8A1/EDNRB/CD38/PRKG1/EPHX2	20
BP	GO:0009101	glycoprotein biosynthetic process	45/2112	348/18670	0.1888	0.3753	0.2712	IGF1/GALNT11/CCL19/IL15/CHST15/CCR7/MGAT4C/EXTL2/B3GALNT1/GALNT10/GOLGA2/TRAK2/HBEGF/CHST3/ALG6/DCN/NPC1/BGN/DPM3/MAGT1/CCL21/CSPG4/TCF7L2/GAL3ST4/CHST11/VCAN/FAM20B/UGDH/VCP/GFPT1/DPY19L4/EXT2/B3GNT2/MAN1C1/SDF2L1/UBE2J1/VEGFB/STT3A/MAN2A2/FUT8/CANT1/GFPT2/FUT4/UBE2G2/B4GALT2	45
BP	GO:1901215	negative regulation of neuron death	28/2112	208/18670	0.1891	0.3757	0.2715	NDNF/CRLF1/GDF5/CORO1A/HLA-F/TNFRSF1B/NTRK2/CD200/ANGPT1/AXL/OXR1/SIX1/ADAM8/JAK2/ITSN1/CX3CR1/SOD1/ZPR1/PIK3CA/MECP2/HSP90AB1/IKBKG/STXBP1/TGFB3/PINK1/HIPK2/CCL2/CHL1	28
BP	GO:0002088	lens development in camera-type eye	12/2112	80/18670	0.1896	0.3763	0.2719	BMP4/CDKN1C/WNT5B/TMOD1/SKI/CDON/MEIS1/CRYAB/SMAD3/HIPK2/ABI2/CRYGB	12
BP	GO:0022617	extracellular matrix disassembly	12/2112	80/18670	0.1896	0.3763	0.2719	LCP1/DDR2/MMP1/HTRA1/ADAM8/TIMP2/CTSL/PDPN/IL6/ADAM10/CTRB2/MMP12	12
BP	GO:0070509	calcium ion import	12/2112	80/18670	0.1896	0.3763	0.2719	CACNA2D1/DYSF/TRPV2/PLN/AFG3L2/MICU1/MS4A1/SLC8A1/SLC25A23/PKD2/CCL2/CASK	12
BP	GO:0045143	homologous chromosome segregation	9/2112	57/18670	0.1906	0.378	0.2731	PTTG1/PTTG3P/PLK1/UBE2B/STAG3/TERF1/REC8/TRIP13/CCNE2	9
BP	GO:0051310	metaphase plate congression	9/2112	57/18670	0.1906	0.378	0.2731	NDC80/GEM/CDCA8/KIF2C/CCNB1/CENPF/CHMP2B/KIFC1/CHMP1B	9
BP	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	9/2112	57/18670	0.1906	0.378	0.2731	SRI/OXCT1/KLF7/MPC2/LRP5/EFNA5/STX4/SYBU/GPR27	9
BP	GO:0044088	regulation of vacuole organization	7/2112	42/18670	0.1914	0.3794	0.2741	PIP4K2B/VPS16/FEZ1/PINK1/SCARB2/PIP4K2A/FEZ2	7
BP	GO:0009791	post-embryonic development	13/2112	88/18670	0.1918	0.3797	0.2744	PLEKHA1/BMP4/BCL11B/NDN/SGPL1/SLC18A2/BAK1/CHST11/EFEMP1/ATRX/MECP2/ERCC1/ALDH5A1	13
BP	GO:0032088	negative regulation of NF-kappaB transcription factor activity	13/2112	88/18670	0.1918	0.3797	0.2744	TRAF3/AIM2/TNFAIP3/CD200/DAP/ADORA3/NFKBIA/TRIM21/GFI1/ANXA4/CAT/USP7/NLRP3	13
BP	GO:0045921	positive regulation of exocytosis	13/2112	88/18670	0.1918	0.3797	0.2744	HLA-F/ITGB2/IL4R/GATA2/FGR/NLGN1/RAB27A/IFNG/STX4/SYK/STXBP1/GAB2/CADPS	13
BP	GO:0106027	neuron projection organization	13/2112	88/18670	0.1918	0.3797	0.2744	DOCK10/ZNF365/WASL/NLGN1/EPHB1/PDLIM5/CTTN/CFL1/ADAM10/DVL1/ABI2/MTMR2/ACTR2	13
BP	GO:0019217	regulation of fatty acid metabolic process	14/2112	96/18670	0.1934	0.3825	0.2763	ACADVL/NFE2L1/CD74/ERLIN1/ACACB/RGN/ADIPOQ/ERLIN2/FABP5/PDK4/NR1H3/ACADL/IL1B/ELOVL5	14
BP	GO:0030219	megakaryocyte differentiation	14/2112	96/18670	0.1934	0.3825	0.2763	PRKCQ/FLI1/MEIS1/GATA2/PTPN6/KMT2A/PTPN11/TESC/PIP4K2A/MYL9/SH2B3/WASF2/GP1BA/PRMT1	14
BP	GO:0090277	positive regulation of peptide hormone secretion	14/2112	96/18670	0.1934	0.3825	0.2763	SRI/OXCT1/JAK2/ITSN1/EGFR/TM7SF3/MPC2/TCF7L2/RBP4/STX4/HFE/CD38/SYBU/GPR27	14
BP	GO:0097327	response to antineoplastic agent	14/2112	96/18670	0.1934	0.3825	0.2763	ICAM1/EGFR/BLM/MAP4K1/ADIRF/PCK1/MAPK13/FOXO1/ATRX/TIMELESS/FOXO3/ADAM10/CFLAR/KIF1B	14
BP	GO:0050806	positive regulation of synaptic transmission	23/2112	168/18670	0.1937	0.3829	0.2767	CCR2/LILRB2/NTRK2/LAMA2/EGFR/SLC1A3/TAC1/NLGN1/CX3CR1/CLSTN1/PTN/CA2/PLK2/KMO/MECP2/STX4/VAMP2/STXBP1/PINK1/LGI1/CYP46A1/DVL1/CCL2	23
BP	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	15/2112	104/18670	0.1946	0.3842	0.2776	PIK3R1/CLU/TNFRSF1B/BCL2A1/CD74/BID/ACKR3/CDIP1/BAK1/TP63/BCL2L2/HIPK2/TP53/MOAP1/PML	15
BP	GO:0032414	positive regulation of ion transmembrane transporter activity	15/2112	104/18670	0.1946	0.3842	0.2776	CCR2/CACNA2D1/ANK2/PLCG2/ATP1B1/IFNG/RGN/FGF14/P2RY6/PINK1/TESC/PKD2/GSTO1/GSTM2/CCL2	15
BP	GO:0046928	regulation of neurotransmitter secretion	15/2112	104/18670	0.1946	0.3842	0.2776	PREPL/MCTP1/PRKCB/PFN2/SNCAIP/NLGN1/HTR2A/CHRNA5/KMO/STXBP1/BACE1/SNCG/DVL1/CASK/P2RY4	15
BP	GO:0032411	positive regulation of transporter activity	16/2112	112/18670	0.1953	0.3853	0.2784	CCR2/CACNA2D1/ANK2/KMT2A/PLCG2/ATP1B1/IFNG/RGN/FGF14/P2RY6/PINK1/TESC/PKD2/GSTO1/GSTM2/CCL2	16
BP	GO:1903828	negative regulation of cellular protein localization	16/2112	112/18670	0.1953	0.3853	0.2784	PID1/GBP1/CSK/ANGPT1/ITGB1BP1/CD36/BARD1/LILRB4/MFHAS1/GDI1/TERF1/ADIPOQ/UBE2J1/FERMT1/UBE2G2/DCLK1	16
BP	GO:0009247	glycolipid biosynthetic process	10/2112	65/18670	0.1953	0.3853	0.2784	PIGK/DPM3/GPAA1/GAL3ST4/FA2H/PIGH/PIGP/PIGT/PIGF/UGCG	10
BP	GO:0030534	adult behavior	20/2112	144/18670	0.1954	0.3853	0.2784	UCHL1/ZIC1/TMOD1/PBX3/GLRB/OXR1/USP46/NPC1/PCDH17/HTR2A/CHRNA5/ADAM22/LEP/PAX5/ATP1A2/MECP2/HOXD10/SNCG/HIPK2/CHL1	20
BP	GO:0035150	regulation of tube size	20/2112	144/18670	0.1954	0.3853	0.2784	GCH1/FOXC1/ITGB1BP1/HBB/ICAM1/COMP/HTR2B/EGFR/PER2/SOD1/HTR2A/HRH1/LEP/AGTR1/ATP1A2/SLC8A1/EDNRB/CD38/PRKG1/EPHX2	20
BP	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	17/2112	120/18670	0.1957	0.3856	0.2786	CDKN1C/SKI/HTRA1/ADAMTSL2/TGFBR3/CREBBP/GLG1/CHST11/PMEPA1/SMAD3/LDLRAD4/HSP90AB1/TGFB3/FERMT1/HIPK2/DKK3/TP53	17
BP	GO:0046939	nucleotide phosphorylation	19/2112	136/18670	0.1957	0.3856	0.2786	IGF1/ZBTB20/SLC2A6/CBFA2T3/NUP93/HDAC4/HK3/NME7/ALDOC/TPR/NUP160/AK1/HTR2A/IFNG/ARNT/NME4/NUP88/NUP50/TP53	19
BP	GO:0051291	protein heterooligomerization	18/2112	128/18670	0.1958	0.3857	0.2787	BIRC3/GCH1/TRPS1/CD74/GLRB/HBB/RRM2/PCBD1/MCCC1/CPSF6/MAGI2/NLGN1/ADIPOQ/PKD2/IKZF1/KRT10/PRKAB1/TMCC1	18
BP	GO:0060271	cilium assembly	47/2112	366/18670	0.1961	0.3862	0.279	GALNT11/DYNC2LI1/TMEM231/CETN2/RAB8A/ABCC4/CBY1/MAP4/NEK1/PLK1/TUBA4A/CDC14B/UBE2B/DZIP1/KIF3B/CDK1/TMEM80/CEP135/TTLL1/TUBB4A/PARVA/C5orf30/NEK2/CLUAP1/TCTN1/ABLIM1/NOTCH1/FNBP1L/ATG3/BBS1/CNTRL/SPAG16/WWTR1/SPAG1/CEP63/BBIP1/SNX10/DYNLRB1/ARL3/ACTR3/RFX4/ATXN10/GSN/NPHP4/ACTR2/LRRC49/AHI1	47
BP	GO:0007018	microtubule-based movement	37/2112	283/18670	0.1962	0.3862	0.279	UCHL1/RASGRP1/DYNC2LI1/MREG/PURA/MAP4/DYNC1LI2/TRAK2/KIF11/KIF15/KIF18B/KIF3B/KIF21B/DLGAP5/TTLL1/KIF2C/KIF4A/DYNC1I1/SOD1/CLUAP1/KIF20A/RACGAP1/FEZ1/KIF16B/TRIM58/HSPB1/MAP1B/SYBU/KIF20B/DYNLRB1/ARL3/FYCO1/ACTR3/KIFC1/KIF1B/ACTR2/KIF23	37
BP	GO:0014904	myotube cell development	6/2112	35/18670	0.1982	0.389	0.281	IGF1/SKI/PPP3CA/SIX1/HDAC4/SHOX2	6
BP	GO:0035909	aorta morphogenesis	6/2112	35/18670	0.1982	0.389	0.281	SIX1/BMPR1A/NOTCH1/HEY2/HEY1/MYLK	6
BP	GO:0042455	ribonucleoside biosynthetic process	6/2112	35/18670	0.1982	0.389	0.281	NT5E/UPP1/ADK/NME7/ADA/NME4	6
BP	GO:0046131	pyrimidine ribonucleoside metabolic process	6/2112	35/18670	0.1982	0.389	0.281	UPP1/APOBEC3G/APOBEC3B/NME7/ENTPD4/NME4	6
BP	GO:0048333	mesodermal cell differentiation	6/2112	35/18670	0.1982	0.389	0.281	BMP4/INHBA/EYA2/BMPR1A/SIX2/HOXA11	6
BP	GO:0051354	negative regulation of oxidoreductase activity	6/2112	35/18670	0.1982	0.389	0.281	GZMA/NFKB1/GFI1/HP/GLA/AOC3	6
BP	GO:0071312	cellular response to alkaloid	6/2112	35/18670	0.1982	0.389	0.281	ICAM1/BLM/CCNA2/SLC8A1/RYR3/GSTM2	6
BP	GO:1902991	regulation of amyloid precursor protein catabolic process	6/2112	35/18670	0.1982	0.389	0.281	IGF1/CLU/ABCG1/SPON1/IFNG/LYN	6
BP	GO:1905332	positive regulation of morphogenesis of an epithelium	6/2112	35/18670	0.1982	0.389	0.281	BMP4/SOX9/AR/SIX1/ITGAX/AHI1	6
BP	GO:1990774	tumor necrosis factor secretion	6/2112	35/18670	0.1982	0.389	0.281	IL27RA/LGALS9/IFIH1/AKAP12/DDX58/IFNG	6
BP	GO:0045333	cellular respiration	26/2112	193/18670	0.1985	0.3893	0.2813	NDUFC1/BID/NDUFS2/CBFA2T3/FASTKD5/NDUFS4/IDH2/CDK1/SLC25A22/ETFB/NDUFA13/SUCLA2/VCP/IFNG/CCNB1/PIK3CA/MECP2/SLC25A23/PINK1/NDUFA9/MDH1/SDHA/NDUFB6/CAT/NDUFA4/ALDH5A1	26
BP	GO:0043627	response to estrogen	11/2112	73/18670	0.1987	0.3893	0.2813	SFRP1/TNFRSF11B/GLI3/GSTM3/IL4R/TRIM24/CA2/CCND1/TGFB3/KRT19/IGFBP2	11
BP	GO:0044766	multi-organism transport	11/2112	73/18670	0.1987	0.3893	0.2813	NUP93/RAB40B/TPR/NUP160/VPS37C/THOC2/KPNA2/NUP88/THOC1/NUP50/THOC6	11
BP	GO:0060350	endochondral bone morphogenesis	11/2112	73/18670	0.1987	0.3893	0.2813	BMP4/SCARA3/FGF18/SOX9/FOXC1/COCH/COMP/SHOX2/COL14A1/ALPL/HOXA11	11
BP	GO:1902579	multi-organism localization	11/2112	73/18670	0.1987	0.3893	0.2813	NUP93/RAB40B/TPR/NUP160/VPS37C/THOC2/KPNA2/NUP88/THOC1/NUP50/THOC6	11
BP	GO:0046390	ribose phosphate biosynthetic process	39/2112	300/18670	0.1989	0.3895	0.2814	PID1/AMPD3/IGF1/ZBTB20/UPP1/ADK/SLC2A6/NPR2/CBFA2T3/SLC26A2/NUP93/HDAC4/HK3/NME7/ALDOC/MPC2/TPR/ACAT1/NUP160/ACACB/AK1/HTR2A/HSD17B12/VCP/IFNG/ARNT/PDK4/PARP1/PINK1/ELOVL4/MPC1/NME4/NUP88/ELOVL2/NUP50/TP53/ACSL5/ELOVL5/PRPS2	39
BP	GO:0009948	anterior/posterior axis specification	8/2112	50/18670	0.1991	0.3896	0.2815	BMP4/LRP6/SKI/WLS/SIX2/HEY2/DDIT3/AURKA	8
BP	GO:0031113	regulation of microtubule polymerization	8/2112	50/18670	0.1991	0.3896	0.2815	TUBB4A/MECP2/TERF1/PAK1/CAMSAP2/MAP1B/CLIP3/CDH5	8
BP	GO:0032784	regulation of DNA-templated transcription, elongation	8/2112	50/18670	0.1991	0.3896	0.2815	CCNT1/TCEA2/EZH2/ZMYND11/BRD4/GTF2F1/PAF1/THOC1	8
BP	GO:0003007	heart morphogenesis	34/2112	259/18670	0.201	0.3932	0.2841	BMP4/SOX9/NPY1R/PIM1/FOXC1/ZFPM2/SIX1/BMPR1A/HTR2B/SHOX2/YAP1/DHRS3/DLC1/TGFBR3/SMARCD3/TMEM100/PARVA/DCHS1/CPE/SMAD3/RBP4/NOTCH1/HEY2/ACVR1/NIPBL/MEGF8/FAT4/HEY1/PKD2/S1PR1/FZD2/TP53/STIL/AHI1	34
BP	GO:0015698	inorganic anion transport	23/2112	169/18670	0.2017	0.3934	0.2842	ENPP1/ANKH/APOL1/PCYOX1/GLRB/FXYD1/SLC26A2/CLCN4/SLC1A3/SLC37A1/CA2/RACGAP1/SLC12A2/P2RY6/SLC12A8/CLIC5/LRRC8D/SLC12A7/CLCN7/CLCN5/CLCC1/P2RY4/PRKG2	23
BP	GO:0030307	positive regulation of cell growth	23/2112	169/18670	0.2017	0.3934	0.2842	SFRP1/S100A9/IGF1/CXCR4/SEMA4D/RPS6KA1/EGFR/HBEGF/SPHK1/TRPV2/ERBB2/LEF1/HYAL1/EFNA5/GDI1/SYT17/PAK1/MAP1B/LGI1/CD38/MEGF8/CYBA/ADAM10	23
BP	GO:0044773	mitotic DNA damage checkpoint	14/2112	97/18670	0.2041	0.3934	0.2842	TFDP2/BLM/E2F8/CDK1/PLK2/DONSON/CCNB1/CCND1/SYF2/PRMT1/PCBP4/TP53/AURKA/PML	14
BP	GO:0051591	response to cAMP	14/2112	97/18670	0.2041	0.3934	0.2842	IGFBP5/CDO1/PENK/STAT1/AQP9/NDUFS4/PCK1/NOX4/ZFP36L1/SLC8A1/ADIPOQ/FOSL1/PKD2/REN	14
BP	GO:0003180	aortic valve morphogenesis	5/2112	28/18670	0.2042	0.3934	0.2842	BMP4/SOX9/NOTCH1/HEY2/RB1	5
BP	GO:0006972	hyperosmotic response	5/2112	28/18670	0.2042	0.3934	0.2842	AKR1B1/MICU1/SLC12A2/SLC25A23/ICOSLG	5
BP	GO:0008045	motor neuron axon guidance	5/2112	28/18670	0.2042	0.3934	0.2842	RAC2/SEMA3A/ERBB2/SEMA3F/CHN1	5
BP	GO:0035116	embryonic hindlimb morphogenesis	5/2112	28/18670	0.2042	0.3934	0.2842	BMP4/ZBTB16/TP63/PITX1/NOTCH1	5
BP	GO:0070861	regulation of protein exit from endoplasmic reticulum	5/2112	28/18670	0.2042	0.3934	0.2842	EDEM1/UBE2J1/CD81/EDEM2/UBE2G2	5
BP	GO:1900543	negative regulation of purine nucleotide metabolic process	5/2112	28/18670	0.2042	0.3934	0.2842	PID1/CBFA2T3/HDAC4/PARP1/TP53	5
BP	GO:1902003	regulation of amyloid-beta formation	5/2112	28/18670	0.2042	0.3934	0.2842	IGF1/CLU/ABCG1/SPON1/IFNG	5
BP	GO:1904994	regulation of leukocyte adhesion to vascular endothelial cell	5/2112	28/18670	0.2042	0.3934	0.2842	CCR2/ITGA4/ITGB2/ICAM1/CCL21	5
BP	GO:1990776	response to angiotensin	5/2112	28/18670	0.2042	0.3934	0.2842	AHCYL1/NFKB1/CA2/AGTR1/CYBA	5
BP	GO:0019229	regulation of vasoconstriction	9/2112	58/18670	0.2046	0.3934	0.2842	ICAM1/EGFR/PER2/HTR2A/HRH1/LEP/AGTR1/ATP1A2/CD38	9
BP	GO:0030520	intracellular estrogen receptor signaling pathway	9/2112	58/18670	0.2046	0.3934	0.2842	RBFOX2/AR/KANK2/YAP1/TAF7/UFSP2/TP63/PAK1/PARP1	9
BP	GO:0035904	aorta development	9/2112	58/18670	0.2046	0.3934	0.2842	MYH10/SIX1/BMPR1A/NOTCH1/LEP/HEY2/HEY1/PKD2/MYLK	9
BP	GO:0098930	axonal transport	9/2112	58/18670	0.2046	0.3934	0.2842	UCHL1/TRAK2/KIF3B/KIF4A/SOD1/FEZ1/HSPB1/SYBU/KIF1B	9
BP	GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors	9/2112	58/18670	0.2046	0.3934	0.2842	SFRP1/TNFAIP3/TIMP3/TNFSF10/ICAM1/HGF/PMAIP1/STX4/CFLAR	9
BP	GO:0006612	protein targeting to membrane	27/2112	202/18670	0.2047	0.3934	0.2842	RTP4/MICALL1/PARD3/ITGB1BP1/ITGB2/PEX26/SEC62/RPL31/RPL24/ERBB2/VPS37C/ICMT/GDI1/SEC63/RPS4X/ZDHHC18/PAK1/RPL12/MYO1C/ATG3/PEX19/RPL15/NCF1/GOLGA7/RPL10A/ZDHHC14/RPS14	27
BP	GO:0008593	regulation of Notch signaling pathway	15/2112	105/18670	0.2048	0.3934	0.2842	GALNT11/ITGB1BP1/NOD2/GATA2/EGFR/CREBBP/NFKBIA/TP63/NOTCH1/IL6ST/HEY2/TSPAN14/ADAM10/HEY1/GDPD5	15
BP	GO:0033138	positive regulation of peptidyl-serine phosphorylation	15/2112	105/18670	0.2048	0.3934	0.2842	NTRK2/ANGPT1/HCLS1/PFN2/PRKD2/RIPK2/EGFR/IFNG/PIK3CA/HSP90AB1/PAK1/PINK1/IL6/PRKD1/IFNA1	15
BP	GO:0018022	peptidyl-lysine methylation	18/2112	129/18670	0.2051	0.3934	0.2842	AUTS2/KMT2A/EZH2/DNMT1/ATRX/BRD4/PAX5/MECP2/MTF2/RLF/GFI1/SUZ12/SMYD2/JARID2/LMNA/SETMAR/EZH1/METTL22	18
BP	GO:0010631	epithelial cell migration	45/2112	351/18670	0.2053	0.3934	0.2842	CXCL13/BMP4/SEMA4A/FGF18/SOX9/SEMA3A/EMP2/ANGPT1/FGF7/PFN2/MAPRE2/ITGB1BP1/ITGB2/KANK2/CD40/PRKD2/ANXA3/SCG2/GATA2/HBEGF/FGF2/DCN/TAC1/SP1/PTN/DOCK1/HYAL1/PTPN11/PLK2/NOTCH1/KANK1/IFNG/PECAM1/PIK3CA/MECP2/PPM1F/HSPB1/PIK3R3/AKT3/FERMT1/PRKD1/KDR/CAPN7/PFN1/CTSH	45
BP	GO:0002091	negative regulation of receptor internalization	3/2112	14/18670	0.2054	0.3934	0.2842	LRPAP1/ATXN2/MTMR2	3
BP	GO:0002834	regulation of response to tumor cell	3/2112	14/18670	0.2054	0.3934	0.2842	CRTAM/CD160/CD226	3
BP	GO:0002837	regulation of immune response to tumor cell	3/2112	14/18670	0.2054	0.3934	0.2842	CRTAM/CD160/CD226	3
BP	GO:0003214	cardiac left ventricle morphogenesis	3/2112	14/18670	0.2054	0.3934	0.2842	CPE/NOTCH1/HEY2	3
BP	GO:0006878	cellular copper ion homeostasis	3/2112	14/18670	0.2054	0.3934	0.2842	SCO2/SLC31A2/PRND	3
BP	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient	3/2112	14/18670	0.2054	0.3934	0.2842	BAK1/ATP1B1/ATP1A2	3
BP	GO:0010421	hydrogen peroxide-mediated programmed cell death	3/2112	14/18670	0.2054	0.3934	0.2842	HGF/PINK1/FOXO3	3
BP	GO:0010457	centriole-centriole cohesion	3/2112	14/18670	0.2054	0.3934	0.2842	CEP135/NEK2/CEP68	3
BP	GO:0010917	negative regulation of mitochondrial membrane potential	3/2112	14/18670	0.2054	0.3934	0.2842	ARL6IP5/PMAIP1/BNIP3L	3
BP	GO:0014819	regulation of skeletal muscle contraction	3/2112	14/18670	0.2054	0.3934	0.2842	KCNJ2/GSTO1/GSTM2	3
BP	GO:0020027	hemoglobin metabolic process	3/2112	14/18670	0.2054	0.3934	0.2842	INHBA/CAT/PRMT1	3
BP	GO:0021781	glial cell fate commitment	3/2112	14/18670	0.2054	0.3934	0.2842	SOX9/NFE2L1/SOX2	3
BP	GO:0030213	hyaluronan biosynthetic process	3/2112	14/18670	0.2054	0.3934	0.2842	NFKB1/HYAL1/IL1B	3
BP	GO:0031272	regulation of pseudopodium assembly	3/2112	14/18670	0.2054	0.3934	0.2842	CCR7/CCL21/CDC42EP3	3
BP	GO:0032310	prostaglandin secretion	3/2112	14/18670	0.2054	0.3934	0.2842	ABCC4/LEP/IL1B	3
BP	GO:0034370	triglyceride-rich lipoprotein particle remodeling	3/2112	14/18670	0.2054	0.3934	0.2842	LIPG/CETP/LIPC	3
BP	GO:0034392	negative regulation of smooth muscle cell apoptotic process	3/2112	14/18670	0.2054	0.3934	0.2842	LRP6/IGF1/DNMT1	3
BP	GO:0035358	regulation of peroxisome proliferator activated receptor signaling pathway	3/2112	14/18670	0.2054	0.3934	0.2842	LMO3/LEP/FABP5	3
BP	GO:0035810	positive regulation of urine volume	3/2112	14/18670	0.2054	0.3934	0.2842	BTC/EDNRB/NPR3	3
BP	GO:0035815	positive regulation of renal sodium excretion	3/2112	14/18670	0.2054	0.3934	0.2842	TAC1/SNX5/EDNRB	3
BP	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process	3/2112	14/18670	0.2054	0.3934	0.2842	PIK3CD/PIK3CA/PIK3R3	3
BP	GO:0038166	angiotensin-activated signaling pathway	3/2112	14/18670	0.2054	0.3934	0.2842	AHCYL1/CA2/AGTR1	3
BP	GO:0040034	regulation of development, heterochronic	3/2112	14/18670	0.2054	0.3934	0.2842	NOTCH1/FGF9/GDPD5	3
BP	GO:0044546	NLRP3 inflammasome complex assembly	3/2112	14/18670	0.2054	0.3934	0.2842	CD36/TLR6/NLRP3	3
BP	GO:0045346	regulation of MHC class II biosynthetic process	3/2112	14/18670	0.2054	0.3934	0.2842	JAK2/IFNG/SPI1	3
BP	GO:0045605	negative regulation of epidermal cell differentiation	3/2112	14/18670	0.2054	0.3934	0.2842	EZH2/TP63/NOTCH1	3
BP	GO:0051547	regulation of keratinocyte migration	3/2112	14/18670	0.2054	0.3934	0.2842	FGF7/MAPRE2/HBEGF	3
BP	GO:0051775	response to redox state	3/2112	14/18670	0.2054	0.3934	0.2842	ARHGDIB/ARNTL/ADH5	3
BP	GO:0055064	chloride ion homeostasis	3/2112	14/18670	0.2054	0.3934	0.2842	SLC12A2/SLC12A8/SLC12A7	3
BP	GO:0060009	Sertoli cell development	3/2112	14/18670	0.2054	0.3934	0.2842	SOX9/ICAM1/ATRX	3
BP	GO:0060732	positive regulation of inositol phosphate biosynthetic process	3/2112	14/18670	0.2054	0.3934	0.2842	HRH1/P2RY6/PTH1R	3
BP	GO:0072425	signal transduction involved in G2 DNA damage checkpoint	3/2112	14/18670	0.2054	0.3934	0.2842	DTL/PLK1/CDC14B	3
BP	GO:0090178	regulation of establishment of planar polarity involved in neural tube closure	3/2112	14/18670	0.2054	0.3934	0.2842	SFRP1/DVL1/FZD2	3
BP	GO:0097154	GABAergic neuron differentiation	3/2112	14/18670	0.2054	0.3934	0.2842	INHBA/GATA2/FEZF2	3
BP	GO:0097468	programmed cell death in response to reactive oxygen species	3/2112	14/18670	0.2054	0.3934	0.2842	HGF/PINK1/FOXO3	3
BP	GO:1901722	regulation of cell proliferation involved in kidney development	3/2112	14/18670	0.2054	0.3934	0.2842	BMP4/PDGFD/CFLAR	3
BP	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	3/2112	14/18670	0.2054	0.3934	0.2842	SFRP1/TIMP3/PMAIP1	3
BP	GO:1903054	negative regulation of extracellular matrix organization	3/2112	14/18670	0.2054	0.3934	0.2842	TNFRSF1B/ANTXR1/NOTCH1	3
BP	GO:1903624	regulation of DNA catabolic process	3/2112	14/18670	0.2054	0.3934	0.2842	RGN/APAF1/IL6	3
BP	GO:1904748	regulation of apoptotic process involved in development	3/2112	14/18670	0.2054	0.3934	0.2842	TNFRSF1B/FOXC1/NOTCH1	3
BP	GO:1904889	regulation of excitatory synapse assembly	3/2112	14/18670	0.2054	0.3934	0.2842	SEMA4A/PTPRD/PTPRS	3
BP	GO:1905049	negative regulation of metallopeptidase activity	3/2112	14/18670	0.2054	0.3934	0.2842	TIMP3/TIMP2/RECK	3
BP	GO:1905064	negative regulation of vascular smooth muscle cell differentiation	3/2112	14/18670	0.2054	0.3934	0.2842	DNMT1/HEY2/FGF9	3
BP	GO:2001279	regulation of unsaturated fatty acid biosynthetic process	3/2112	14/18670	0.2054	0.3934	0.2842	CD74/FABP5/IL1B	3
BP	GO:0099504	synaptic vesicle cycle	26/2112	194/18670	0.2061	0.3942	0.2848	PREPL/PRKCB/PFN2/GAK/ITSN1/SLC18A2/DNM1/DENND1A/MAGI2/PLD1/NLGN1/PCDH17/CDH2/HTR2A/CHRNA5/FGF14/SYT17/STX4/VAMP2/STXBP1/BACE1/DVL1/STX6/CASK/P2RY4/CADPS	26
BP	GO:0009260	ribonucleotide biosynthetic process	38/2112	293/18670	0.2067	0.3942	0.2848	PID1/AMPD3/IGF1/ZBTB20/UPP1/ADK/SLC2A6/NPR2/CBFA2T3/SLC26A2/NUP93/HDAC4/HK3/NME7/ALDOC/MPC2/TPR/ACAT1/NUP160/ACACB/AK1/HTR2A/HSD17B12/VCP/IFNG/ARNT/PDK4/PARP1/PINK1/ELOVL4/MPC1/NME4/NUP88/ELOVL2/NUP50/TP53/ACSL5/ELOVL5	38
BP	GO:0003094	glomerular filtration	4/2112	21/18670	0.2078	0.3942	0.2848	EMP2/XPNPEP3/SULF1/CORO2B	4
BP	GO:0006293	nucleotide-excision repair, preincision complex stabilization	4/2112	21/18670	0.2078	0.3942	0.2848	PARP1/CUL4B/ERCC1/GTF2H5	4
BP	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion	4/2112	21/18670	0.2078	0.3942	0.2848	PARP1/CUL4B/ERCC1/GTF2H5	4
BP	GO:0009081	branched-chain amino acid metabolic process	4/2112	21/18670	0.2078	0.3942	0.2848	ALDH6A1/MCCC1/ACAT1/BCKDHB	4
BP	GO:0009083	branched-chain amino acid catabolic process	4/2112	21/18670	0.2078	0.3942	0.2848	ALDH6A1/MCCC1/ACAT1/BCKDHB	4
BP	GO:0030277	maintenance of gastrointestinal epithelium	4/2112	21/18670	0.2078	0.3942	0.2848	SERPINA3/SOX9/NOD2/RBP4	4
BP	GO:0031290	retinal ganglion cell axon guidance	4/2112	21/18670	0.2078	0.3942	0.2848	RPL24/EPHB1/EFNA5/SEMA4F	4
BP	GO:0031498	chromatin disassembly	4/2112	21/18670	0.2078	0.3942	0.2848	SMARCD3/SMARCC2/SMARCD1/HMGA1	4
BP	GO:0032516	positive regulation of phosphoprotein phosphatase activity	4/2112	21/18670	0.2078	0.3942	0.2848	PTPRC/JAK2/MAGI2/HSP90AB1	4
BP	GO:0032986	protein-DNA complex disassembly	4/2112	21/18670	0.2078	0.3942	0.2848	SMARCD3/SMARCC2/SMARCD1/HMGA1	4
BP	GO:0035590	purinergic nucleotide receptor signaling pathway	4/2112	21/18670	0.2078	0.3942	0.2848	GPR171/P2RY6/P2RY14/P2RY4	4
BP	GO:0035813	regulation of renal sodium excretion	4/2112	21/18670	0.2078	0.3942	0.2848	TAC1/SNX5/AGTR1/EDNRB	4
BP	GO:0036120	cellular response to platelet-derived growth factor stimulus	4/2112	21/18670	0.2078	0.3942	0.2848	PDGFD/CCNA2/PTN/HYAL1	4
BP	GO:0036150	phosphatidylserine acyl-chain remodeling	4/2112	21/18670	0.2078	0.3942	0.2848	PLA2G2D/LPCAT3/PLA2G12A/PLA1A	4
BP	GO:0036344	platelet morphogenesis	4/2112	21/18670	0.2078	0.3942	0.2848	PTPN6/PTPN11/WDR1/NBEAL2	4
BP	GO:0036499	PERK-mediated unfolded protein response	4/2112	21/18670	0.2078	0.3942	0.2848	PTPN2/CXCL8/DDIT3/CCL2	4
BP	GO:0042402	cellular biogenic amine catabolic process	4/2112	21/18670	0.2078	0.3942	0.2848	IDO1/ALDH7A1/KYNU/KMO	4
BP	GO:0050951	sensory perception of temperature stimulus	4/2112	21/18670	0.2078	0.3942	0.2848	CXCR4/EPHB1/HTR2A/LXN	4
BP	GO:0051412	response to corticosterone	4/2112	21/18670	0.2078	0.3942	0.2848	CCND1/FOSL1/MAOB/FOXO3	4
BP	GO:0051900	regulation of mitochondrial depolarization	4/2112	21/18670	0.2078	0.3942	0.2848	DCN/MYOC/PARP1/KDR	4
BP	GO:0060044	negative regulation of cardiac muscle cell proliferation	4/2112	21/18670	0.2078	0.3942	0.2848	MEIS1/KCNK2/RBP4/JARID2	4
BP	GO:0070734	histone H3-K27 methylation	4/2112	21/18670	0.2078	0.3942	0.2848	EZH2/MTF2/SUZ12/EZH1	4
BP	GO:0070920	regulation of production of small RNA involved in gene silencing by RNA	4/2112	21/18670	0.2078	0.3942	0.2848	BMP4/PPP3CA/EGFR/TP53	4
BP	GO:0072111	cell proliferation involved in kidney development	4/2112	21/18670	0.2078	0.3942	0.2848	BMP4/STAT1/PDGFD/CFLAR	4
BP	GO:2000114	regulation of establishment of cell polarity	4/2112	21/18670	0.2078	0.3942	0.2848	KANK1/KIF20B/GSN/CDH5	4
BP	GO:0001953	negative regulation of cell-matrix adhesion	7/2112	43/18670	0.2079	0.3942	0.2848	PIK3R1/ITGB1BP1/DLC1/MYOC/SEMA3E/CASK/MMP12	7
BP	GO:0021795	cerebral cortex cell migration	7/2112	43/18670	0.2079	0.3942	0.2848	GLI3/SEMA3A/EGFR/FGF13/DIXDC1/POU3F3/MBOAT7	7
BP	GO:0046460	neutral lipid biosynthetic process	7/2112	43/18670	0.2079	0.3942	0.2848	GK/PLCE1/SIK1/PCK1/RGN/NR1H3/ANG	7
BP	GO:0046463	acylglycerol biosynthetic process	7/2112	43/18670	0.2079	0.3942	0.2848	GK/PLCE1/SIK1/PCK1/RGN/NR1H3/ANG	7
BP	GO:0060612	adipose tissue development	7/2112	43/18670	0.2079	0.3942	0.2848	FTO/OXCT1/KLF7/ACAT1/LRP5/LEP/PIK3CA	7
BP	GO:0086004	regulation of cardiac muscle cell contraction	7/2112	43/18670	0.2079	0.3942	0.2848	SRI/ANK2/FGF13/PLN/KCNJ2/DSC2/ATP1A2	7
BP	GO:0034976	response to endoplasmic reticulum stress	37/2112	285/18670	0.2086	0.3953	0.2856	PIK3R1/CLU/SERINC3/ACADVL/NFE2L1/PTPN2/EXTL2/THBS4/CXCL8/SEC31A/CREB3L2/ERLIN1/BAK1/TSPYL2/PPP2CB/PMAIP1/EDEM1/KDELR3/VCP/GFPT1/FKBP14/CCND1/ERLIN2/APAF1/SDF2L1/RCN3/DDIT3/LMNA/UBE2J1/MBTPS2/EDEM2/TATDN2/CASP4/TP53/CCL2/UBE2G2/PML	37
BP	GO:0060998	regulation of dendritic spine development	11/2112	74/18670	0.2113	0.4002	0.2891	DLG5/LPAR1/ITSN1/NLGN1/PDLIM5/PTPRS/PLK2/CFL1/ADAM10/ABI2/ACTR2	11
BP	GO:1901616	organic hydroxy compound catabolic process	11/2112	74/18670	0.2113	0.4002	0.2891	GK/FAH/AKR1C3/DIO2/SCARF1/MAOA/INPP1/MAOB/CYP46A1/DIO3/MTMR2	11
BP	GO:0032642	regulation of chemokine production	12/2112	82/18670	0.2131	0.4033	0.2914	TLR2/CD74/IL4R/LGALS9/RIPK2/CLEC7A/IFNG/ADIPOQ/SYK/IL6/CXCL6/IL1B	12
BP	GO:0051702	interaction with symbiont	12/2112	82/18670	0.2131	0.4033	0.2914	CCL5/NUCKS1/CHD1/PC/IFI27/CCNT1/SP1/LEF1/FBXL2/CFL1/CXCL6/PTX3	12
BP	GO:0055117	regulation of cardiac muscle contraction	12/2112	82/18670	0.2131	0.4033	0.2914	SRI/ANK2/HDAC4/FGF13/PLN/KCNJ2/ATP1B1/DSC2/ATP1A2/SLC8A1/GSTO1/GSTM2	12
BP	GO:0071158	positive regulation of cell cycle arrest	12/2112	82/18670	0.2131	0.4033	0.2914	TFDP2/CRLF3/E2F8/CDK1/PLK2/CCNB1/PKD2/PRMT1/PCBP4/TP53/AURKA/PML	12
BP	GO:0009135	purine nucleoside diphosphate metabolic process	19/2112	138/18670	0.2138	0.4043	0.2921	AMPD3/IGF1/ZBTB20/SLC2A6/CBFA2T3/NUP93/HDAC4/HK3/ALDOC/TPR/NUP160/AK1/HTR2A/IFNG/ARNT/NUP88/NUP50/TP53/CASK	19
BP	GO:0009179	purine ribonucleoside diphosphate metabolic process	19/2112	138/18670	0.2138	0.4043	0.2921	AMPD3/IGF1/ZBTB20/SLC2A6/CBFA2T3/NUP93/HDAC4/HK3/ALDOC/TPR/NUP160/AK1/HTR2A/IFNG/ARNT/NUP88/NUP50/TP53/CASK	19
BP	GO:0030901	midbrain development	13/2112	90/18670	0.2144	0.405	0.2926	SFRP1/LRP6/DLG5/PLP1/WLS/RYK/ZNF148/CASP5/FGF9/MAOB/FZD6/KDM7A/NDRG2	13
BP	GO:0000731	DNA synthesis involved in DNA repair	8/2112	51/18670	0.2145	0.405	0.2926	DTL/UBE2L6/REV3L/RFC3/VCP/POLE2/USP10/ISG15	8
BP	GO:0031103	axon regeneration	8/2112	51/18670	0.2145	0.405	0.2926	JAM3/JAK2/DAG1/SCARF1/PTPRF/PTN/PTPRS/MAP1B	8
BP	GO:0032206	positive regulation of telomere maintenance	8/2112	51/18670	0.2145	0.405	0.2926	PRKCQ/NEK7/NEK2/ATRX/AURKB/ERCC1/PARN/PML	8
BP	GO:0072523	purine-containing compound catabolic process	8/2112	51/18670	0.2145	0.405	0.2926	AMPD3/NT5E/ADA/PDE1A/ACAT1/NUDT11/PNP/HINT1	8
BP	GO:0099175	regulation of postsynapse organization	14/2112	98/18670	0.2151	0.4059	0.2933	LILRB2/PTPRD/ARHGAP22/NLGN1/PTN/PDLIM5/CDH2/PTPRS/SEMA3F/CHMP2B/CFL1/ADAM10/ABI2/ACTR2	14
BP	GO:0005976	polysaccharide metabolic process	16/2112	114/18670	0.2153	0.4061	0.2934	ENPP1/IGF1/PPP1R3C/EXTL2/PASK/PHKB/PER2/NFKB1/IL6ST/PPP1CA/SORBS1/AOAH/EXT2/B3GNT2/UGP2/MANBA	16
BP	GO:0007127	meiosis I	16/2112	114/18670	0.2153	0.4061	0.2934	PTTG1/PTTG3P/PLK1/UBE2B/CDC25B/TOP2A/MYBL1/RMI1/CKS2/STAG3/TERF1/FBXO5/REC8/TRIP13/CCNE2/AURKA	16
BP	GO:0051963	regulation of synapse assembly	15/2112	106/18670	0.2153	0.4061	0.2934	SEMA4A/DLG5/SEMA4D/NTRK2/TLR2/PTPRD/SIX1/NLGN1/CLSTN1/EPHB1/PDLIM5/PTPRS/EFNA5/GPC4/LRRN3	15
BP	GO:0006882	cellular zinc ion homeostasis	6/2112	36/18670	0.2168	0.4079	0.2947	LCK/S100A9/SLC39A8/SLC39A6/SLC39A7/MT1X	6
BP	GO:0010453	regulation of cell fate commitment	6/2112	36/18670	0.2168	0.4079	0.2947	BMP4/AR/BMPR1A/FGF2/TBX21/FZD7	6
BP	GO:0030224	monocyte differentiation	6/2112	36/18670	0.2168	0.4079	0.2947	BMP4/PIR/CD74/IRF7/ZFP36L1/INPP5D	6
BP	GO:0071392	cellular response to estradiol stimulus	6/2112	36/18670	0.2168	0.4079	0.2947	SFRP1/EGFR/CCNA2/BCL2L2/CFLAR/NRIP1	6
BP	GO:0090313	regulation of protein targeting to membrane	6/2112	36/18670	0.2168	0.4079	0.2947	ITGB1BP1/ITGB2/ERBB2/GDI1/PAK1/MYO1C	6
BP	GO:1903131	mononuclear cell differentiation	6/2112	36/18670	0.2168	0.4079	0.2947	BMP4/PIR/CD74/IRF7/ZFP36L1/INPP5D	6
BP	GO:2000310	regulation of NMDA receptor activity	6/2112	36/18670	0.2168	0.4079	0.2947	CCR2/ANXA3/NLGN1/IFNG/PINK1/CCL2	6
BP	GO:0016241	regulation of macroautophagy	23/2112	171/18670	0.2181	0.4103	0.2965	UCHL1/PIP4K2B/RIPK2/DCN/NPC1/SNX5/FEZ1/PIK3CA/IKBKG/PINK1/PIP4K2A/SESN1/NOD1/EPM2A/KDR/FEZ2/FYCO1/WAC/TP53/BNIP3L/PRKAB1/ATP6V1B2/PIM2	23
BP	GO:0001885	endothelial cell development	9/2112	59/18670	0.219	0.4115	0.2973	GSTM3/ICAM1/ARHGEF26/PPP1R16B/PTPRS/TNMD/PECAM1/IL1B/CDH5	9
BP	GO:0031102	neuron projection regeneration	9/2112	59/18670	0.219	0.4115	0.2973	JAM3/JAK2/DAG1/HGF/SCARF1/PTPRF/PTN/PTPRS/MAP1B	9
BP	GO:0045843	negative regulation of striated muscle tissue development	9/2112	59/18670	0.219	0.4115	0.2973	BMP4/MEIS1/KCNK2/EPHB1/LEF1/FZD7/RBP4/PAK1/JARID2	9
BP	GO:2000756	regulation of peptidyl-lysine acetylation	9/2112	59/18670	0.219	0.4115	0.2973	NAP1L2/AUTS2/GATA2/KMT2A/TAF7/RPS6KA4/EID1/SPI1/IL1B	9
BP	GO:0097479	synaptic vesicle localization	22/2112	163/18670	0.2195	0.4123	0.2979	PREPL/PRKCB/PFN2/DNM1/MAGI2/NLGN1/PCDH17/TMEM230/CDH2/HTR2A/CHRNA5/RAB27A/SYT17/STX4/VAMP2/STXBP1/PINK1/BACE1/DVL1/CASK/P2RY4/CADPS	22
BP	GO:0031669	cellular response to nutrient levels	31/2112	237/18670	0.2199	0.4128	0.2983	SFRP1/PENK/GABARAPL1/IL15/PIM1/AKR1C3/UPP1/KANK2/ICAM1/TRIM24/GABARAPL2/DAP/SIK1/PCK1/PTN/SOD1/PMAIP1/FOXO1/LEP/HIGD1A/DSC2/PDK4/HFE/BCL11A/RYR3/CYBA/PRKD1/SESN1/TP53/P2RY4/TXN2	31
BP	GO:0019359	nicotinamide nucleotide biosynthetic process	20/2112	147/18670	0.222	0.4166	0.301	IGF1/IDO1/ZBTB20/KYNU/SLC2A6/CBFA2T3/NUP93/HDAC4/HK3/ALDOC/IDH2/TPR/NUP160/HTR2A/IFNG/ARNT/KMO/NUP88/NUP50/TP53	20
BP	GO:0019363	pyridine nucleotide biosynthetic process	20/2112	147/18670	0.222	0.4166	0.301	IGF1/IDO1/ZBTB20/KYNU/SLC2A6/CBFA2T3/NUP93/HDAC4/HK3/ALDOC/IDH2/TPR/NUP160/HTR2A/IFNG/ARNT/KMO/NUP88/NUP50/TP53	20
BP	GO:0051298	centrosome duplication	10/2112	67/18670	0.2221	0.4166	0.301	CETN2/CEP135/ARHGEF10/PLK2/CHMP2B/CEP63/PKD2/CCNF/CHMP1B/STIL	10
BP	GO:0090132	epithelium migration	45/2112	354/18670	0.2225	0.4172	0.3015	CXCL13/BMP4/SEMA4A/FGF18/SOX9/SEMA3A/EMP2/ANGPT1/FGF7/PFN2/MAPRE2/ITGB1BP1/ITGB2/KANK2/CD40/PRKD2/ANXA3/SCG2/GATA2/HBEGF/FGF2/DCN/TAC1/SP1/PTN/DOCK1/HYAL1/PTPN11/PLK2/NOTCH1/KANK1/IFNG/PECAM1/PIK3CA/MECP2/PPM1F/HSPB1/PIK3R3/AKT3/FERMT1/PRKD1/KDR/CAPN7/PFN1/CTSH	45
BP	GO:0016571	histone methylation	19/2112	139/18670	0.2231	0.4182	0.3022	AUTS2/KMT2A/EZH2/DNMT1/ATRX/BRD4/PAX5/MECP2/MTF2/RLF/GFI1/PAF1/SUZ12/SMYD2/JARID2/LMNA/PRMT1/SETMAR/EZH1	19
BP	GO:0033135	regulation of peptidyl-serine phosphorylation	19/2112	139/18670	0.2231	0.4182	0.3022	NTRK2/ANGPT1/HCLS1/PFN2/PRKD2/RIPK2/EGFR/BAK1/HGF/IFNG/PIK3CA/PPM1F/HSP90AB1/PAK1/PINK1/IL6/PRKD1/IFNA1/GPD1L	19
BP	GO:0009142	nucleoside triphosphate biosynthetic process	25/2112	188/18670	0.2232	0.4183	0.3022	PID1/IGF1/ZBTB20/ADK/SLC2A6/CBFA2T3/NUP93/HDAC4/HK3/NME7/ALDOC/TPR/NUP160/AK1/HTR2A/VCP/IFNG/ARNT/PARP1/PINK1/TYMS/NME4/NUP88/NUP50/TP53	25
BP	GO:0010611	regulation of cardiac muscle hypertrophy	11/2112	75/18670	0.2241	0.4189	0.3027	IGF1/TNFRSF1B/PPP3CA/FOXO1/SMAD3/NOTCH1/IL6ST/PAK1/PARP1/JARID2/LMNA	11
BP	GO:0043242	negative regulation of protein complex disassembly	11/2112	75/18670	0.2241	0.4189	0.3027	ADD3/TMOD1/CKAP2/FGF13/LMOD1/CAMSAP2/MAP1B/CAPZA1/VILL/SPTBN1/GSN	11
BP	GO:0006378	mRNA polyadenylation	7/2112	44/18670	0.2249	0.4189	0.3027	CPEB1/CPSF6/CCNT1/AHCYL1/CSTF2/PAF1/CLP1	7
BP	GO:0007080	mitotic metaphase plate congression	7/2112	44/18670	0.2249	0.4189	0.3027	NDC80/CDCA8/KIF2C/CCNB1/CHMP2B/KIFC1/CHMP1B	7
BP	GO:0042987	amyloid precursor protein catabolic process	7/2112	44/18670	0.2249	0.4189	0.3027	IGF1/CLU/ABCG1/SPON1/IFNG/ADAM10/LYN	7
BP	GO:0090382	phagosome maturation	7/2112	44/18670	0.2249	0.4189	0.3027	SLAMF8/CORO1A/MREG/TCIRG1/RAB20/ATP6V1B2/RAB14	7
BP	GO:0060218	hematopoietic stem cell differentiation	12/2112	83/18670	0.2254	0.4189	0.3027	PSMB9/SFRP1/PSMB8/PSMB10/BATF/FOXC1/YAP1/GATA2/PSME1/MEOX1/KMT2A/TP53	12
BP	GO:1903845	negative regulation of cellular response to transforming growth factor beta stimulus	12/2112	83/18670	0.2254	0.4189	0.3027	SKI/HTRA1/ADAMTSL2/TGFBR3/GLG1/CHST11/PMEPA1/SMAD3/LDLRAD4/TGFB3/CFLAR/TP53	12
BP	GO:0005979	regulation of glycogen biosynthetic process	5/2112	29/18670	0.2254	0.4189	0.3027	ENPP1/IGF1/PASK/PPP1CA/SORBS1	5
BP	GO:0007263	nitric oxide mediated signal transduction	5/2112	29/18670	0.2254	0.4189	0.3027	NDNF/CD36/EGFR/DDAH2/FPR1	5
BP	GO:0007271	synaptic transmission, cholinergic	5/2112	29/18670	0.2254	0.4189	0.3027	NQO1/LAMA2/TAC1/CHRNA5/RIC3	5
BP	GO:0010575	positive regulation of vascular endothelial growth factor production	5/2112	29/18670	0.2254	0.4189	0.3027	SULF1/IL6ST/ARNT/IL6/IL1B	5
BP	GO:0010644	cell communication by electrical coupling	5/2112	29/18670	0.2254	0.4189	0.3027	SRI/ATP1B1/ATP1A2/SLC8A1/GJC1	5
BP	GO:0010962	regulation of glucan biosynthetic process	5/2112	29/18670	0.2254	0.4189	0.3027	ENPP1/IGF1/PASK/PPP1CA/SORBS1	5
BP	GO:0015949	nucleobase-containing small molecule interconversion	5/2112	29/18670	0.2254	0.4189	0.3027	RRM2/AK1/TYMS/NME4/AK6	5
BP	GO:0018200	peptidyl-glutamic acid modification	5/2112	29/18670	0.2254	0.4189	0.3027	VKORC1/TTLL1/PARP1/FOLH1/TPGS2	5
BP	GO:0030970	retrograde protein transport, ER to cytosol	5/2112	29/18670	0.2254	0.4189	0.3027	EDEM1/VCP/UBE2J1/EDEM2/UBE2G2	5
BP	GO:0033014	tetrapyrrole biosynthetic process	5/2112	29/18670	0.2254	0.4189	0.3027	NFE2L1/SUCLA2/ALAS1/HMBS/ALAD	5
BP	GO:0035025	positive regulation of Rho protein signal transduction	5/2112	29/18670	0.2254	0.4189	0.3027	LPAR1/GPR18/GPR65/AKAP13/GPR4	5
BP	GO:0045822	negative regulation of heart contraction	5/2112	29/18670	0.2254	0.4189	0.3027	SRI/JAK2/TAC1/PLN/ATP1A2	5
BP	GO:0045980	negative regulation of nucleotide metabolic process	5/2112	29/18670	0.2254	0.4189	0.3027	PID1/CBFA2T3/HDAC4/PARP1/TP53	5
BP	GO:0051642	centrosome localization	5/2112	29/18670	0.2254	0.4189	0.3027	ASPM/PARD3/MAD2L1/DYNC1LI2/AURKA	5
BP	GO:0060142	regulation of syncytium formation by plasma membrane fusion	5/2112	29/18670	0.2254	0.4189	0.3027	CXCL9/IL4R/CXCL10/CD53/CFLAR	5
BP	GO:0060536	cartilage morphogenesis	5/2112	29/18670	0.2254	0.4189	0.3027	LRP6/SCARA3/COCH/COL14A1/HOXA5	5
BP	GO:0070528	protein kinase C signaling	5/2112	29/18670	0.2254	0.4189	0.3027	CD40/HTR2B/AKAP12/PLEK/GPD1L	5
BP	GO:1903513	endoplasmic reticulum to cytosol transport	5/2112	29/18670	0.2254	0.4189	0.3027	EDEM1/VCP/UBE2J1/EDEM2/UBE2G2	5
BP	GO:2000171	negative regulation of dendrite development	5/2112	29/18670	0.2254	0.4189	0.3027	PPP3CA/NLGN1/PTPRS/PLK2/BCL11A	5
BP	GO:0006096	glycolytic process	16/2112	115/18670	0.2257	0.4191	0.3028	IGF1/ZBTB20/SLC2A6/CBFA2T3/NUP93/HDAC4/HK3/ALDOC/TPR/NUP160/HTR2A/IFNG/ARNT/NUP88/NUP50/TP53	16
BP	GO:0010927	cellular component assembly involved in morphogenesis	16/2112	115/18670	0.2257	0.4191	0.3028	MYH10/TMOD1/ANK2/TLR2/DAG1/PMP22/CD9/LMOD1/KRT19/AKAP13/MYH11/MPP5/TENM4/WDR1/CFLAR/MTMR2	16
BP	GO:0009145	purine nucleoside triphosphate biosynthetic process	23/2112	172/18670	0.2266	0.4207	0.304	PID1/IGF1/ZBTB20/ADK/SLC2A6/CBFA2T3/NUP93/HDAC4/HK3/NME7/ALDOC/TPR/NUP160/HTR2A/VCP/IFNG/ARNT/PARP1/PINK1/NME4/NUP88/NUP50/TP53	23
BP	GO:0009156	ribonucleoside monophosphate biosynthetic process	26/2112	197/18670	0.2295	0.4259	0.3078	PID1/AMPD3/IGF1/ZBTB20/UPP1/ADK/SLC2A6/CBFA2T3/NUP93/HDAC4/HK3/ADA/ALDOC/TPR/NUP160/AK1/HTR2A/VCP/IFNG/ARNT/PARP1/PINK1/NUP88/NUP50/TP53/PRPS2	26
BP	GO:0016573	histone acetylation	21/2112	156/18670	0.2297	0.4263	0.308	NAP1L2/ING3/IRF4/AUTS2/BAZ1A/GATA2/CREBBP/KMT2A/TAF7/RPS6KA4/LEF1/EID1/MECP2/MSL3/MBIP/KAT6B/SPI1/PHF10/RSF1/MORF4L1/IL1B	21
BP	GO:2000649	regulation of sodium ion transmembrane transporter activity	8/2112	52/18670	0.2303	0.4271	0.3086	FXYD1/FXYD6/NETO2/ATP1B1/SCN1B/ATP1A2/TESC/GPD1L	8
BP	GO:2000772	regulation of cellular senescence	8/2112	52/18670	0.2303	0.4271	0.3086	HLA-G/BMPR1A/PLK2/ARNTL/FBXO5/AKT3/HMGA1/TP53	8
BP	GO:1903364	positive regulation of cellular protein catabolic process	19/2112	140/18670	0.2327	0.4293	0.3102	TNFAIP3/CLU/CBFA2T3/CTSC/PLK1/CHFR/BAG2/EDEM1/PLK2/VCP/RGN/DACT1/RNF19B/CEBPA/DVL1/CD81/EDEM2/AURKA/RNF14	19
BP	GO:0000717	nucleotide-excision repair, DNA duplex unwinding	4/2112	22/18670	0.2329	0.4293	0.3102	CETN2/PARP1/CUL4B/GTF2H5	4
BP	GO:0001759	organ induction	4/2112	22/18670	0.2329	0.4293	0.3102	BMP4/AR/SIX1/HOXA11	4
BP	GO:0006085	acetyl-CoA biosynthetic process	4/2112	22/18670	0.2329	0.4293	0.3102	MPC2/ACAT1/PDK4/MPC1	4
BP	GO:0006783	heme biosynthetic process	4/2112	22/18670	0.2329	0.4293	0.3102	NFE2L1/ALAS1/HMBS/ALAD	4
BP	GO:0018230	peptidyl-L-cysteine S-palmitoylation	4/2112	22/18670	0.2329	0.4293	0.3102	ZDHHC18/CLIP3/GOLGA7/ZDHHC14	4
BP	GO:0018231	peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine	4/2112	22/18670	0.2329	0.4293	0.3102	ZDHHC18/CLIP3/GOLGA7/ZDHHC14	4
BP	GO:0030878	thyroid gland development	4/2112	22/18670	0.2329	0.4293	0.3102	SIX1/SMAD3/HOXA5/THRA	4
BP	GO:0035809	regulation of urine volume	4/2112	22/18670	0.2329	0.4293	0.3102	BTC/AKR1B1/EDNRB/NPR3	4
BP	GO:0042359	vitamin D metabolic process	4/2112	22/18670	0.2329	0.4293	0.3102	NFKB1/IFNG/GFI1/IL1B	4
BP	GO:0043496	regulation of protein homodimerization activity	4/2112	22/18670	0.2329	0.4293	0.3102	ITGA4/PCBD1/BAK1/CRBN	4
BP	GO:0045717	negative regulation of fatty acid biosynthetic process	4/2112	22/18670	0.2329	0.4293	0.3102	ACADVL/ERLIN1/ERLIN2/ACADL	4
BP	GO:0051000	positive regulation of nitric-oxide synthase activity	4/2112	22/18670	0.2329	0.4293	0.3102	GCH1/HTR2B/NOD1/NPR3	4
BP	GO:0051195	negative regulation of cofactor metabolic process	4/2112	22/18670	0.2329	0.4293	0.3102	CBFA2T3/HDAC4/HP/TP53	4
BP	GO:0070935	3'-UTR-mediated mRNA stabilization	4/2112	22/18670	0.2329	0.4293	0.3102	MYD88/HNRNPA0/DAZL/MAPKAPK2	4
BP	GO:0071359	cellular response to dsRNA	4/2112	22/18670	0.2329	0.4293	0.3102	IFIH1/DDX58/NFKB1/COLEC12	4
BP	GO:0090189	regulation of branching involved in ureteric bud morphogenesis	4/2112	22/18670	0.2329	0.4293	0.3102	BMP4/SOX9/SIX1/SIX2	4
BP	GO:0097205	renal filtration	4/2112	22/18670	0.2329	0.4293	0.3102	EMP2/XPNPEP3/SULF1/CORO2B	4
BP	GO:0097320	plasma membrane tubulation	4/2112	22/18670	0.2329	0.4293	0.3102	BIN2/MICALL1/WASL/FNBP1L	4
BP	GO:1903589	positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	4/2112	22/18670	0.2329	0.4293	0.3102	GATA2/PPP1R16B/AGTR1/APLNR	4
BP	GO:0051147	regulation of muscle cell differentiation	24/2112	181/18670	0.2333	0.4297	0.3105	CXCL9/BMP4/IGF1/CDON/IL4R/HDAC4/SHOX2/CXCL10/SMARCD3/SIK1/EZH2/CDH2/CD53/DNMT1/CEACAM5/BHLHE41/FZD7/NOTCH1/MECP2/HEY2/PAK1/FGF9/AKAP13/CFLAR	24
BP	GO:0033013	tetrapyrrole metabolic process	9/2112	60/18670	0.2338	0.4297	0.3105	NFE2L1/SUCLA2/ALAS1/BDH2/CD320/HMBS/CTRB2/ALAD/LMBRD1	9
BP	GO:0048635	negative regulation of muscle organ development	9/2112	60/18670	0.2338	0.4297	0.3105	BMP4/MEIS1/KCNK2/EPHB1/LEF1/FZD7/RBP4/PAK1/JARID2	9
BP	GO:0090342	regulation of cell aging	9/2112	60/18670	0.2338	0.4297	0.3105	HLA-G/BMPR1A/PLK2/ARNTL/FBXO5/AKT3/LMNA/HMGA1/TP53	9
BP	GO:0003018	vascular process in circulatory system	23/2112	173/18670	0.2352	0.4297	0.3105	GCH1/FOXC1/ANGPT1/ITGB1BP1/HBB/ICAM1/COMP/HTR2B/EGFR/AKAP12/PER2/SOD1/HTR2A/HRH1/LEP/AGTR1/ATP1A2/SLC8A1/EDNRB/CD38/PRKG1/EPHX2/CDH5	23
BP	GO:0032885	regulation of polysaccharide biosynthetic process	6/2112	37/18670	0.2359	0.4297	0.3105	ENPP1/IGF1/PASK/NFKB1/PPP1CA/SORBS1	6
BP	GO:0045923	positive regulation of fatty acid metabolic process	6/2112	37/18670	0.2359	0.4297	0.3105	CD74/RGN/ADIPOQ/NR1H3/IL1B/ELOVL5	6
BP	GO:0051567	histone H3-K9 methylation	6/2112	37/18670	0.2359	0.4297	0.3105	DNMT1/ATRX/PAX5/MECP2/JARID2/LMNA	6
BP	GO:0071276	cellular response to cadmium ion	6/2112	37/18670	0.2359	0.4297	0.3105	AKR1C3/EGFR/SOD1/NCF1/GSN/MT1X	6
BP	GO:0086010	membrane depolarization during action potential	6/2112	37/18670	0.2359	0.4297	0.3105	CACNA2D1/ANK2/KCNJ2/SCN1B/ATP1A2/SLC8A1	6
BP	GO:2000249	regulation of actin cytoskeleton reorganization	6/2112	37/18670	0.2359	0.4297	0.3105	ARHGDIB/HCLS1/GMFG/RHOD/SEMA3E/HCK	6
BP	GO:0051965	positive regulation of synapse assembly	10/2112	68/18670	0.236	0.4297	0.3105	SEMA4A/DLG5/SEMA4D/NTRK2/PTPRD/NLGN1/CLSTN1/EPHB1/EFNA5/LRRN3	10
BP	GO:0006757	ATP generation from ADP	16/2112	116/18670	0.2362	0.4297	0.3105	IGF1/ZBTB20/SLC2A6/CBFA2T3/NUP93/HDAC4/HK3/ALDOC/TPR/NUP160/HTR2A/IFNG/ARNT/NUP88/NUP50/TP53	16
BP	GO:0001325	formation of extrachromosomal circular DNA	3/2112	15/18670	0.2366	0.4297	0.3105	BLM/TERF1/ERCC1	3
BP	GO:0006098	pentose-phosphate shunt	3/2112	15/18670	0.2366	0.4297	0.3105	RPIA/PGD/TALDO1	3
BP	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation	3/2112	15/18670	0.2366	0.4297	0.3105	CSTF2/DDX1/CLP1	3
BP	GO:0006491	N-glycan processing	3/2112	15/18670	0.2366	0.4297	0.3105	MAN1C1/MAN2A2/FUT8	3
BP	GO:0009263	deoxyribonucleotide biosynthetic process	3/2112	15/18670	0.2366	0.4297	0.3105	ADK/RRM2/TYMS	3
BP	GO:0014874	response to stimulus involved in regulation of muscle adaptation	3/2112	15/18670	0.2366	0.4297	0.3105	SGCA/HDAC4/DAG1	3
BP	GO:0015671	oxygen transport	3/2112	15/18670	0.2366	0.4297	0.3105	HBB/IPCEF1/HBD	3
BP	GO:0030238	male sex determination	3/2112	15/18670	0.2366	0.4297	0.3105	SOX9/AR/FGF9	3
BP	GO:0030812	negative regulation of nucleotide catabolic process	3/2112	15/18670	0.2366	0.4297	0.3105	CBFA2T3/HDAC4/TP53	3
BP	GO:0032239	regulation of nucleobase-containing compound transport	3/2112	15/18670	0.2366	0.4297	0.3105	CPSF6/TPR/KHDRBS1	3
BP	GO:0032352	positive regulation of hormone metabolic process	3/2112	15/18670	0.2366	0.4297	0.3105	IFNG/ARNT/IL1B	3
BP	GO:0032988	ribonucleoprotein complex disassembly	3/2112	15/18670	0.2366	0.4297	0.3105	VCP/DHX8/ZFAND1	3
BP	GO:0033151	V(D)J recombination	3/2112	15/18670	0.2366	0.4297	0.3105	BCL11B/TCF7/LEF1	3
BP	GO:0034111	negative regulation of homotypic cell-cell adhesion	3/2112	15/18670	0.2366	0.4297	0.3105	CD9/PRKG1/SH2B3	3
BP	GO:0035635	entry of bacterium into host cell	3/2112	15/18670	0.2366	0.4297	0.3105	CXCL8/KRT6A/ITGAV	3
BP	GO:0043650	dicarboxylic acid biosynthetic process	3/2112	15/18670	0.2366	0.4297	0.3105	KYNU/SLC1A3/KMO	3
BP	GO:0044406	adhesion of symbiont to host	3/2112	15/18670	0.2366	0.4297	0.3105	ICAM1/HSP90AB1/CD81	3
BP	GO:0045342	MHC class II biosynthetic process	3/2112	15/18670	0.2366	0.4297	0.3105	JAK2/IFNG/SPI1	3
BP	GO:0051198	negative regulation of coenzyme metabolic process	3/2112	15/18670	0.2366	0.4297	0.3105	CBFA2T3/HDAC4/TP53	3
BP	GO:0060026	convergent extension	3/2112	15/18670	0.2366	0.4297	0.3105	SFRP1/LRP6/DVL1	3
BP	GO:0060099	regulation of phagocytosis, engulfment	3/2112	15/18670	0.2366	0.4297	0.3105	CD36/GATA2/NCKAP1L	3
BP	GO:0060339	negative regulation of type I interferon-mediated signaling pathway	3/2112	15/18670	0.2366	0.4297	0.3105	PTPN2/ADAR/MMP12	3
BP	GO:0071474	cellular hyperosmotic response	3/2112	15/18670	0.2366	0.4297	0.3105	AKR1B1/MICU1/SLC25A23	3
BP	GO:0071599	otic vesicle development	3/2112	15/18670	0.2366	0.4297	0.3105	SOX9/SIX1/AHI1	3
BP	GO:0071801	regulation of podosome assembly	3/2112	15/18670	0.2366	0.4297	0.3105	LCP1/HCK/GSN	3
BP	GO:0072075	metanephric mesenchyme development	3/2112	15/18670	0.2366	0.4297	0.3105	STAT1/SIX1/PKD2	3
BP	GO:0072148	epithelial cell fate commitment	3/2112	15/18670	0.2366	0.4297	0.3105	PDPN/NOTCH1/ACVR1	3
BP	GO:0072283	metanephric renal vesicle morphogenesis	3/2112	15/18670	0.2366	0.4297	0.3105	BMP4/STAT1/SIX2	3
BP	GO:0090141	positive regulation of mitochondrial fission	3/2112	15/18670	0.2366	0.4297	0.3105	DCN/PINK1/KDR	3
BP	GO:0090177	establishment of planar polarity involved in neural tube closure	3/2112	15/18670	0.2366	0.4297	0.3105	SFRP1/DVL1/FZD2	3
BP	GO:0090656	t-circle formation	3/2112	15/18670	0.2366	0.4297	0.3105	BLM/TERF1/ERCC1	3
BP	GO:0090737	telomere maintenance via telomere trimming	3/2112	15/18670	0.2366	0.4297	0.3105	BLM/TERF1/ERCC1	3
BP	GO:1900029	positive regulation of ruffle assembly	3/2112	15/18670	0.2366	0.4297	0.3105	COBL/NLGN1/PFN1	3
BP	GO:1900239	regulation of phenotypic switching	3/2112	15/18670	0.2366	0.4297	0.3105	SP1/DNMT1/FGF9	3
BP	GO:1902187	negative regulation of viral release from host cell	3/2112	15/18670	0.2366	0.4297	0.3105	TRIM21/TRIM26/PML	3
BP	GO:1903729	regulation of plasma membrane organization	3/2112	15/18670	0.2366	0.4297	0.3105	AR/WASL/GSN	3
BP	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway	3/2112	15/18670	0.2366	0.4297	0.3105	SFRP1/PLEKHA4/DACT1	3
BP	GO:0050680	negative regulation of epithelial cell proliferation	22/2112	165/18670	0.237	0.4304	0.311	SFRP1/GDF5/BMP4/RUNX3/CDKN1C/STAT1/SOX9/AR/SULF1/SCG2/TGFBR3/NFIB/SOX2/PTN/TNMD/RGN/PRL/RB1/CCL2/EAF2/CASK/LIMS2	22
BP	GO:0019674	NAD metabolic process	11/2112	76/18670	0.2373	0.4306	0.3111	NT5E/IDO1/KYNU/HK3/ALDOC/VCP/KMO/MDH1/CD38/TP53/GPD1L	11
BP	GO:0048844	artery morphogenesis	11/2112	76/18670	0.2373	0.4306	0.3111	BMP4/FOXC1/SIX1/BMPR1A/COMP/NOTCH1/HEY2/AKT3/HEY1/PKD2/MYLK	11
BP	GO:0060840	artery development	14/2112	100/18670	0.2377	0.4312	0.3115	BMP4/MYH10/GLI3/FOXC1/SIX1/BMPR1A/COMP/NOTCH1/LEP/HEY2/AKT3/HEY1/PKD2/MYLK	14
BP	GO:0050886	endocrine process	12/2112	84/18670	0.2379	0.4312	0.3115	INHBA/TAC1/FZD4/PTPN11/LEP/AGTR1/OR51E2/CPA3/CYBA/REN/IL1B/RAB11FIP1	12
BP	GO:1902803	regulation of synaptic vesicle transport	12/2112	84/18670	0.2379	0.4312	0.3115	PREPL/PRKCB/PFN2/NLGN1/HTR2A/CHRNA5/STXBP1/PINK1/BACE1/DVL1/CASK/P2RY4	12
BP	GO:1905897	regulation of response to endoplasmic reticulum stress	12/2112	84/18670	0.2379	0.4312	0.3115	PIK3R1/CLU/SERINC3/NFE2L1/PTPN2/BAK1/PMAIP1/EDEM1/DDIT3/UBE2J1/EDEM2/UBE2G2	12
BP	GO:0001764	neuron migration	21/2112	157/18670	0.2388	0.4328	0.3127	NDNF/ASPM/MYH10/CXCR4/NDN/NTRK2/SEMA3A/SPOCK1/AXL/AUTS2/GATA2/TUBB2B/FGF13/NIPBL/MARK1/MAP1B/PRKG1/KIF20B/FEZF2/DCLK1/CHL1	21
BP	GO:0071248	cellular response to metal ion	25/2112	190/18670	0.2397	0.4342	0.3137	CPNE3/NQO1/AKR1C3/NFE2L1/EGFR/NLGN1/SOD1/ECT2/CCNB1/TFAP2A/SYT17/PARP1/SLC25A23/HFE/BACE1/RYR3/GUCA1A/FABP4/CEBPA/FSTL3/PKD2/NCF1/ALAD/GSN/MT1X	25
BP	GO:2000058	regulation of ubiquitin-dependent protein catabolic process	20/2112	149/18670	0.2406	0.4358	0.3149	CLU/CBFA2T3/PLK1/CHFR/PLK2/VCP/HSP90AB1/HFE/RNF19B/CEBPA/HIPK2/DVL1/BAG5/WAC/PBK/USP7/CAMLG/AURKA/RNF14/PML	20
BP	GO:0032309	icosanoid secretion	7/2112	45/18670	0.2424	0.4382	0.3166	PLA2G2D/ABCC4/NMB/PLA2G12A/LEP/SYK/IL1B	7
BP	GO:0032456	endocytic recycling	7/2112	45/18670	0.2424	0.4382	0.3166	MICALL1/DENND1C/DENND1A/EHD4/ARL4C/STX6/RAB14	7
BP	GO:0035987	endodermal cell differentiation	7/2112	45/18670	0.2424	0.4382	0.3166	ITGA4/INHBA/ITGB2/COL8A1/SOX2/PAF1/ITGAV	7
BP	GO:0044275	cellular carbohydrate catabolic process	7/2112	45/18670	0.2424	0.4382	0.3166	GK/PHKB/PGD/PPP1CA/AOAH/SCARB2/MANBA	7
BP	GO:0048483	autonomic nervous system development	7/2112	45/18670	0.2424	0.4382	0.3166	SEMA3A/SIX1/TP63/SEMA3F/NAV2/TFAP2A/EDNRB	7
BP	GO:0070316	regulation of G0 to G1 transition	7/2112	45/18670	0.2424	0.4382	0.3166	TFDP2/RRM2/HLA-G/EZH2/CDC7/SUZ12/APAF1	7
BP	GO:0071827	plasma lipoprotein particle organization	7/2112	45/18670	0.2424	0.4382	0.3166	ABCG1/LIPG/AGTR1/CETP/LIPC/PLA2G7/SOAT2	7
BP	GO:0006941	striated muscle contraction	23/2112	174/18670	0.2439	0.4407	0.3184	CXCR4/SYNM/SRI/CACNA2D1/ANK2/HDAC4/KCNJ5/PLN/SGCD/KCNJ2/ATP1B1/SCN1B/KCNJ8/DSC2/ATP1A2/PIK3CA/SLC8A1/VEGFB/GSTO1/GJC1/GSTM2/SNTA1/GPD1L	23
BP	GO:0001508	action potential	18/2112	133/18670	0.244	0.4407	0.3184	SRI/NTRK2/CACNA2D1/ANK2/CD36/KCNJ5/TAC1/FGF13/KCNJ2/ATP1B1/SCN1B/KCNJ8/DSC2/ATP1A2/SLC8A1/GJC1/SNTA1/GPD1L	18
BP	GO:0006475	internal protein amino acid acetylation	22/2112	166/18670	0.246	0.4442	0.321	NAP1L2/ING3/IRF4/AUTS2/BAZ1A/GATA2/CREBBP/KMT2A/TAF7/PCK1/RPS6KA4/LEF1/EID1/MECP2/MSL3/MBIP/KAT6B/SPI1/PHF10/RSF1/MORF4L1/IL1B	22
BP	GO:0045744	negative regulation of G protein-coupled receptor signaling pathway	8/2112	53/18670	0.2465	0.4445	0.3212	CCL5/HTR2B/DNM1/ADA/CXCL8/PLEK/GPRASP1/APLNR	8
BP	GO:1901185	negative regulation of ERBB signaling pathway	8/2112	53/18670	0.2465	0.4445	0.3212	BTC/PTPN2/EGFR/GPRC5A/HBEGF/ERBB2/ZGPAT/SNX5	8
BP	GO:0010822	positive regulation of mitochondrion organization	16/2112	117/18670	0.247	0.4445	0.3212	TFDP2/RAC2/GZMB/BID/TNFSF10/DCN/BAK1/TP63/PMAIP1/FAM162A/PINK1/KDR/HSPA1L/TP53BP2/TP53/MOAP1	16
BP	GO:0022904	respiratory electron transport chain	16/2112	117/18670	0.247	0.4445	0.3212	NDUFC1/BID/NDUFS2/NDUFS4/CDK1/SLC25A22/ETFB/NDUFA13/CCNB1/MECP2/PINK1/NDUFA9/SDHA/NDUFB6/NDUFA4/ALDH5A1	16
BP	GO:0000027	ribosomal large subunit assembly	5/2112	30/18670	0.2473	0.4445	0.3212	RPL24/RPL12/RSL24D1/NLE1/MRPL20	5
BP	GO:0006517	protein deglycosylation	5/2112	30/18670	0.2473	0.4445	0.3212	EDEM1/MAN1C1/MAN2B1/EDEM2/MAN2A2	5
BP	GO:0034243	regulation of transcription elongation from RNA polymerase II promoter	5/2112	30/18670	0.2473	0.4445	0.3212	EZH2/ZMYND11/BRD4/GTF2F1/PAF1	5
BP	GO:0038111	interleukin-7-mediated signaling pathway	5/2112	30/18670	0.2473	0.4445	0.3212	IL2RG/IL7R/SOCS1/CISH/SOCS2	5
BP	GO:0042759	long-chain fatty acid biosynthetic process	5/2112	30/18670	0.2473	0.4445	0.3212	LTC4S/PLP1/GPX4/EPHX2/ALOX5	5
BP	GO:0043171	peptide catabolic process	5/2112	30/18670	0.2473	0.4445	0.3212	ERAP2/CPQ/TRHDE/ANPEP/CTSH	5
BP	GO:0061842	microtubule organizing center localization	5/2112	30/18670	0.2473	0.4445	0.3212	ASPM/PARD3/MAD2L1/DYNC1LI2/AURKA	5
BP	GO:0071549	cellular response to dexamethasone stimulus	5/2112	30/18670	0.2473	0.4445	0.3212	ICAM1/EGFR/PCK1/FOXO1/CFLAR	5
BP	GO:0090314	positive regulation of protein targeting to membrane	5/2112	30/18670	0.2473	0.4445	0.3212	ITGB1BP1/ITGB2/ERBB2/PAK1/MYO1C	5
BP	GO:0099068	postsynapse assembly	5/2112	30/18670	0.2473	0.4445	0.3212	PTPRD/MAGI2/NLGN1/CDH2/PTPRS	5
BP	GO:1904893	negative regulation of STAT cascade	5/2112	30/18670	0.2473	0.4445	0.3212	PPP2CA/PTPN2/SOCS1/SOCS2/SH2B3	5
BP	GO:1905476	negative regulation of protein localization to membrane	5/2112	30/18670	0.2473	0.4445	0.3212	PID1/GBP1/CSK/ITGB1BP1/GDI1	5
BP	GO:0006879	cellular iron ion homeostasis	9/2112	61/18670	0.2489	0.4469	0.3229	SRI/SKP1/SLC22A17/CYBRD1/CP/TFRC/SOD1/HFE/NDFIP1	9
BP	GO:1905953	negative regulation of lipid localization	9/2112	61/18670	0.2489	0.4469	0.3229	ABCG1/PTPN2/NFKBIA/NFKB1/PTPN11/LEP/IL6/NR1H3/ITGAV	9
BP	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	9/2112	61/18670	0.2489	0.4469	0.3229	LCK/S100A9/SERINC3/BID/PTPN2/SOD1/PMAIP1/DDIT3/TP53	9
BP	GO:1901184	regulation of ERBB signaling pathway	13/2112	93/18670	0.2501	0.4487	0.3242	BTC/RHBDF2/PTPN2/EGFR/GPRC5A/HBEGF/ERBB2/ZGPAT/RHBDF1/SNX5/FER/NCF1/SH3TC2	13
BP	GO:0072525	pyridine-containing compound biosynthetic process	20/2112	150/18670	0.2502	0.4487	0.3242	IGF1/IDO1/ZBTB20/KYNU/SLC2A6/CBFA2T3/NUP93/HDAC4/HK3/ALDOC/IDH2/TPR/NUP160/HTR2A/IFNG/ARNT/KMO/NUP88/NUP50/TP53	20
BP	GO:0008088	axo-dendritic transport	10/2112	69/18670	0.2502	0.4487	0.3242	UCHL1/PURA/TRAK2/KIF3B/KIF4A/SOD1/FEZ1/HSPB1/SYBU/KIF1B	10
BP	GO:0034381	plasma lipoprotein particle clearance	10/2112	69/18670	0.2502	0.4487	0.3242	CSK/CD36/NPC1/LRPAP1/LIPG/MYLIP/ADIPOQ/HDLBP/LIPC/SOAT2	10
BP	GO:0009127	purine nucleoside monophosphate biosynthetic process	24/2112	183/18670	0.2504	0.4487	0.3242	PID1/AMPD3/IGF1/ZBTB20/ADK/SLC2A6/CBFA2T3/NUP93/HDAC4/HK3/ADA/ALDOC/TPR/NUP160/AK1/HTR2A/VCP/IFNG/ARNT/PARP1/PINK1/NUP88/NUP50/TP53	24
BP	GO:0009168	purine ribonucleoside monophosphate biosynthetic process	24/2112	183/18670	0.2504	0.4487	0.3242	PID1/AMPD3/IGF1/ZBTB20/ADK/SLC2A6/CBFA2T3/NUP93/HDAC4/HK3/ADA/ALDOC/TPR/NUP160/AK1/HTR2A/VCP/IFNG/ARNT/PARP1/PINK1/NUP88/NUP50/TP53	24
BP	GO:0021953	central nervous system neuron differentiation	24/2112	183/18670	0.2504	0.4487	0.3242	SFRP1/BCL11B/LRP6/HOXC10/GLI3/NTRK2/TSKU/SEMA3A/INHBA/SPOCK1/NFE2L1/GATA2/NFIB/EPHB1/RYK/TCTN1/SCN1B/LEP/HSP90AB1/HOXD10/TULP3/FEZF2/GDPD5/DCLK1	24
BP	GO:0002028	regulation of sodium ion transport	12/2112	85/18670	0.2506	0.4487	0.3242	FXYD1/FXYD6/NETO2/SIK1/AHCYL1/ATP1B1/SCN1B/ATP1A2/SLC8A1/TESC/SNTA1/GPD1L	12
BP	GO:1904705	regulation of vascular smooth muscle cell proliferation	12/2112	85/18670	0.2506	0.4487	0.3242	IGFBP5/IGF1/BMPR1A/JAK2/FGF2/DNMT1/PAK1/ADIPOQ/P2RY6/FGF9/TGFB3/PRKG1	12
BP	GO:1990874	vascular smooth muscle cell proliferation	12/2112	85/18670	0.2506	0.4487	0.3242	IGFBP5/IGF1/BMPR1A/JAK2/FGF2/DNMT1/PAK1/ADIPOQ/P2RY6/FGF9/TGFB3/PRKG1	12
BP	GO:0044782	cilium organization	48/2112	384/18670	0.2507	0.4487	0.3242	GALNT11/DYNC2LI1/TMEM231/CETN2/RAB8A/ABCC4/CBY1/MAP4/NEK1/PLK1/TUBA4A/CDC14B/UBE2B/DZIP1/KIF3B/CDK1/TMEM80/CEP135/TTLL1/TUBB4A/PARVA/C5orf30/NEK2/CLUAP1/TCTN1/ABLIM1/NOTCH1/FNBP1L/ATG3/BBS1/CNTRL/SPAG16/WWTR1/SPAG1/CEP63/BBIP1/SNX10/PKD2/DYNLRB1/ARL3/ACTR3/RFX4/ATXN10/GSN/NPHP4/ACTR2/LRRC49/AHI1	48
BP	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	11/2112	77/18670	0.2507	0.4487	0.3242	PSMB9/PSMB8/PSMB10/PSME1/CREBBP/BACH1/NOTCH1/HIGD1A/ARNT/CUL2/TP53	11
BP	GO:0006778	porphyrin-containing compound metabolic process	6/2112	38/18670	0.2555	0.4564	0.3298	NFE2L1/SUCLA2/ALAS1/BDH2/HMBS/ALAD	6
BP	GO:0050892	intestinal absorption	6/2112	38/18670	0.2555	0.4564	0.3298	CD36/AKR1C1/LEP/UGCG/SLC2A5/SOAT2	6
BP	GO:0055069	zinc ion homeostasis	6/2112	38/18670	0.2555	0.4564	0.3298	LCK/S100A9/SLC39A8/SLC39A6/SLC39A7/MT1X	6
BP	GO:0086005	ventricular cardiac muscle cell action potential	6/2112	38/18670	0.2555	0.4564	0.3298	ANK2/KCNJ5/KCNJ8/DSC2/SNTA1/GPD1L	6
BP	GO:0086091	regulation of heart rate by cardiac conduction	6/2112	38/18670	0.2555	0.4564	0.3298	CACNA2D1/ANK2/KCNJ5/KCNJ2/SCN1B/DSC2	6
BP	GO:1903523	negative regulation of blood circulation	6/2112	38/18670	0.2555	0.4564	0.3298	SRI/JAK2/TAC1/PLN/LEP/ATP1A2	6
BP	GO:2000279	negative regulation of DNA biosynthetic process	6/2112	38/18670	0.2555	0.4564	0.3298	KCNK2/RGN/TERF1/ADIPOQ/TP53/DNAJC2	6
BP	GO:0072331	signal transduction by p53 class mediator	34/2112	267/18670	0.256	0.457	0.3302	TFDP2/BATF/CD74/TPX2/CDIP1/TRIM24/BLM/E2F8/TAF7/BARD1/CDK1/TP63/RFC3/PMAIP1/RMI1/ATRX/PLK2/HEXIM1/CCNB1/CHD4/SMYD2/FOXO3/AURKB/HIPK2/TP53BP2/PRMT1/PCBP4/HINT1/USP10/TP53/PRKAB1/AURKA/TOPBP1/PML	34
BP	GO:0006541	glutamine metabolic process	4/2112	23/18670	0.2587	0.4601	0.3324	GFPT1/MECP2/GFPT2/ALDH5A1	4
BP	GO:0007064	mitotic sister chromatid cohesion	4/2112	23/18670	0.2587	0.4601	0.3324	ATRX/NIPBL/RB1/CDC20	4
BP	GO:0009068	aspartate family amino acid catabolic process	4/2112	23/18670	0.2587	0.4601	0.3324	ALDH7A1/ASPA/MAT1A/AASS	4
BP	GO:0009310	amine catabolic process	4/2112	23/18670	0.2587	0.4601	0.3324	IDO1/ALDH7A1/KYNU/KMO	4
BP	GO:0032959	inositol trisphosphate biosynthetic process	4/2112	23/18670	0.2587	0.4601	0.3324	PLCE1/PLCG2/HRH1/P2RY6	4
BP	GO:0035812	renal sodium excretion	4/2112	23/18670	0.2587	0.4601	0.3324	TAC1/SNX5/AGTR1/EDNRB	4
BP	GO:0051151	negative regulation of smooth muscle cell differentiation	4/2112	23/18670	0.2587	0.4601	0.3324	DNMT1/MECP2/HEY2/FGF9	4
BP	GO:0051882	mitochondrial depolarization	4/2112	23/18670	0.2587	0.4601	0.3324	DCN/MYOC/PARP1/KDR	4
BP	GO:0070841	inclusion body assembly	4/2112	23/18670	0.2587	0.4601	0.3324	CLU/SNCAIP/VCP/BAG5	4
BP	GO:0071157	negative regulation of cell cycle arrest	4/2112	23/18670	0.2587	0.4601	0.3324	EVI2B/HSP90AB1/CCND1/SETMAR	4
BP	GO:0089718	amino acid import across plasma membrane	4/2112	23/18670	0.2587	0.4601	0.3324	SLC1A3/PER2/ARL6IP5/ATP1A2	4
BP	GO:0090343	positive regulation of cell aging	4/2112	23/18670	0.2587	0.4601	0.3324	HLA-G/LMNA/HMGA1/TP53	4
BP	GO:2000050	regulation of non-canonical Wnt signaling pathway	4/2112	23/18670	0.2587	0.4601	0.3324	SFRP1/PLEKHA4/DAAM2/DACT1	4
BP	GO:0090130	tissue migration	45/2112	360/18670	0.2589	0.4603	0.3326	CXCL13/BMP4/SEMA4A/FGF18/SOX9/SEMA3A/EMP2/ANGPT1/FGF7/PFN2/MAPRE2/ITGB1BP1/ITGB2/KANK2/CD40/PRKD2/ANXA3/SCG2/GATA2/HBEGF/FGF2/DCN/TAC1/SP1/PTN/DOCK1/HYAL1/PTPN11/PLK2/NOTCH1/KANK1/IFNG/PECAM1/PIK3CA/MECP2/PPM1F/HSPB1/PIK3R3/AKT3/FERMT1/PRKD1/KDR/CAPN7/PFN1/CTSH	45
BP	GO:0001504	neurotransmitter uptake	7/2112	46/18670	0.2603	0.4624	0.3341	SLC18A2/SLC29A1/SLC1A3/PER2/ARL6IP5/ATP1A2/SLC29A2	7
BP	GO:0043631	RNA polyadenylation	7/2112	46/18670	0.2603	0.4624	0.3341	CPEB1/CPSF6/CCNT1/AHCYL1/CSTF2/PAF1/CLP1	7
BP	GO:0044003	modification by symbiont of host morphology or physiology	7/2112	46/18670	0.2603	0.4624	0.3341	DAG1/SMAD3/KRT6A/TYMS/KPNA2/HIPK2/ITGAV	7
BP	GO:0051646	mitochondrion localization	7/2112	46/18670	0.2603	0.4624	0.3341	UCHL1/TRAK2/FEZ1/MARK1/MAP1B/SYBU/KIF1B	7
BP	GO:0030879	mammary gland development	19/2112	143/18670	0.2622	0.4656	0.3364	BMP4/IGFBP5/LRP6/CDO1/SOX9/GLI3/OAS2/AR/PAM/JAK2/ETV5/SOCS2/LRP5/LEF1/PRL/CCND1/TGFB3/HOXA5/PML	19
BP	GO:0021515	cell differentiation in spinal cord	8/2112	54/18670	0.263	0.4665	0.337	HOXC10/GLI3/NFE2L1/GATA2/TCTN1/NOTCH1/HOXD10/GDPD5	8
BP	GO:0030199	collagen fibril organization	8/2112	54/18670	0.263	0.4665	0.337	FMOD/DDR2/DPT/FOXC1/COMP/COL14A1/LUM/RB1	8
BP	GO:0061512	protein localization to cilium	8/2112	54/18670	0.263	0.4665	0.337	DZIP1/TCTN1/BBS1/TULP3/BBIP1/SNX10/ARL3/NPHP4	8
BP	GO:1900047	negative regulation of hemostasis	8/2112	54/18670	0.263	0.4665	0.337	COMP/PROS1/PLAT/CD9/PRKG1/TFPI/SH2B3/GP1BA	8
BP	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	12/2112	86/18670	0.2637	0.4674	0.3377	PIK3R1/SFRP1/TNFAIP3/TIMP3/BID/TNFSF10/ICAM1/HGF/PMAIP1/STX4/CFLAR/MOAP1	12
BP	GO:0042446	hormone biosynthetic process	12/2112	86/18670	0.2637	0.4674	0.3377	AKR1C3/DIO2/AKR1B1/NFKB1/HSD17B12/IFNG/ARNT/GFI1/HFE/DIO3/DKK3/IL1B	12
BP	GO:0010676	positive regulation of cellular carbohydrate metabolic process	9/2112	62/18670	0.2643	0.4679	0.3381	IGF1/PTPN2/PMAIP1/FOXO1/HRH1/RGN/P2RY6/SORBS1/PTH1R	9
BP	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	9/2112	62/18670	0.2643	0.4679	0.3381	SERINC3/PTPN2/BAK1/PMAIP1/APAF1/DDIT3/CASP4/TP53/PML	9
BP	GO:1902305	regulation of sodium ion transmembrane transport	9/2112	62/18670	0.2643	0.4679	0.3381	FXYD1/FXYD6/NETO2/ATP1B1/SCN1B/ATP1A2/TESC/SNTA1/GPD1L	9
BP	GO:1905268	negative regulation of chromatin organization	9/2112	62/18670	0.2643	0.4679	0.3381	SKI/UBE2B/TAF7/DNMT1/PAX5/MTF2/SPI1/JARID2/HMGA1	9
BP	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	22/2112	168/18670	0.2644	0.4679	0.3381	PCDH9/PCDHB3/CDH19/ANXA3/PCDHB13/PCDHB11/PCDHGA3/CLSTN1/PCDH17/CDH2/CADM1/DCHS1/CEACAM5/PCDHGC3/DSC2/PECAM1/FAT4/PCDHGA9/MPZL2/PCDHB6/PCDHB12/CDH5	22
BP	GO:2000300	regulation of synaptic vesicle exocytosis	11/2112	78/18670	0.2644	0.4679	0.3381	PREPL/PRKCB/PFN2/NLGN1/HTR2A/CHRNA5/STXBP1/BACE1/DVL1/CASK/P2RY4	11
BP	GO:0009755	hormone-mediated signaling pathway	30/2112	235/18670	0.2673	0.4702	0.3397	SFRP1/BMP4/RBFOX2/LMO3/AR/KANK2/JAK2/YAP1/TAF7/UFSP2/PGRMC2/LANCL2/TP63/PMEPA1/LEF1/PTPN11/ARNTL/SSTR5/OR51E2/PAK1/PARP1/CALCOCO1/AKAP13/NR1H3/RB1/RWDD1/REN/NRIP1/RNF14/THRA	30
BP	GO:0000394	RNA splicing, via endonucleolytic cleavage and ligation	3/2112	16/18670	0.2685	0.4702	0.3397	CSTF2/DDX1/CLP1	3
BP	GO:0001946	lymphangiogenesis	3/2112	16/18670	0.2685	0.4702	0.3397	PTPN14/FOXC1/PDPN	3
BP	GO:0001977	renal system process involved in regulation of blood volume	3/2112	16/18670	0.2685	0.4702	0.3397	EMP2/CORO2B/CYBA	3
BP	GO:0003222	ventricular trabecula myocardium morphogenesis	3/2112	16/18670	0.2685	0.4702	0.3397	BMPR1A/NOTCH1/HEY2	3
BP	GO:0006004	fucose metabolic process	3/2112	16/18670	0.2685	0.4702	0.3397	FUCA1/FUT8/FUT4	3
BP	GO:0006047	UDP-N-acetylglucosamine metabolic process	3/2112	16/18670	0.2685	0.4702	0.3397	NAGK/GFPT1/GFPT2	3
BP	GO:0006086	acetyl-CoA biosynthetic process from pyruvate	3/2112	16/18670	0.2685	0.4702	0.3397	MPC2/PDK4/MPC1	3
BP	GO:0006206	pyrimidine nucleobase metabolic process	3/2112	16/18670	0.2685	0.4702	0.3397	TYMP/ALDH6A1/TYMS	3
BP	GO:0010885	regulation of cholesterol storage	3/2112	16/18670	0.2685	0.4702	0.3397	ABCG1/CD36/NR1H3	3
BP	GO:0016540	protein autoprocessing	3/2112	16/18670	0.2685	0.4702	0.3397	AFG3L2/CASP1/PARP1	3
BP	GO:0019372	lipoxygenase pathway	3/2112	16/18670	0.2685	0.4702	0.3397	LTC4S/GPX4/ALOX5	3
BP	GO:0021542	dentate gyrus development	3/2112	16/18670	0.2685	0.4702	0.3397	LEF1/EMX2/FEZF2	3
BP	GO:0030575	nuclear body organization	3/2112	16/18670	0.2685	0.4702	0.3397	ZPR1/HIPK2/PML	3
BP	GO:0031269	pseudopodium assembly	3/2112	16/18670	0.2685	0.4702	0.3397	CCR7/CCL21/CDC42EP3	3
BP	GO:0031958	corticosteroid receptor signaling pathway	3/2112	16/18670	0.2685	0.4702	0.3397	LMO3/JAK2/ARNTL	3
BP	GO:0034116	positive regulation of heterotypic cell-cell adhesion	3/2112	16/18670	0.2685	0.4702	0.3397	LCK/SKAP1/IL1B	3
BP	GO:0035372	protein localization to microtubule	3/2112	16/18670	0.2685	0.4702	0.3397	MAPRE2/DVL1/KIF20B	3
BP	GO:0036124	histone H3-K9 trimethylation	3/2112	16/18670	0.2685	0.4702	0.3397	ATRX/MECP2/LMNA	3
BP	GO:0044794	positive regulation by host of viral process	3/2112	16/18670	0.2685	0.4702	0.3397	NUCKS1/PC/CFL1	3
BP	GO:0044827	modulation by host of viral genome replication	3/2112	16/18670	0.2685	0.4702	0.3397	NUCKS1/IFI27/FBXL2	3
BP	GO:0045618	positive regulation of keratinocyte differentiation	3/2112	16/18670	0.2685	0.4702	0.3397	PRKCH/FOXC1/NOTCH1	3
BP	GO:0046325	negative regulation of glucose import	3/2112	16/18670	0.2685	0.4702	0.3397	ENPP1/PID1/LEP	3
BP	GO:0048012	hepatocyte growth factor receptor signaling pathway	3/2112	16/18670	0.2685	0.4702	0.3397	PTPN2/HGF/PAK1	3
BP	GO:0048385	regulation of retinoic acid receptor signaling pathway	3/2112	16/18670	0.2685	0.4702	0.3397	AKR1C3/DHRS3/EZH2	3
BP	GO:0051503	adenine nucleotide transport	3/2112	16/18670	0.2685	0.4702	0.3397	SLC25A4/SLC25A23/SLC25A5	3
BP	GO:0051571	positive regulation of histone H3-K4 methylation	3/2112	16/18670	0.2685	0.4702	0.3397	AUTS2/KMT2A/DNMT1	3
BP	GO:0060628	regulation of ER to Golgi vesicle-mediated transport	3/2112	16/18670	0.2685	0.4702	0.3397	GAS1/YIPF5/STX18	3
BP	GO:0070863	positive regulation of protein exit from endoplasmic reticulum	3/2112	16/18670	0.2685	0.4702	0.3397	EDEM1/CD81/EDEM2	3
BP	GO:0071732	cellular response to nitric oxide	3/2112	16/18670	0.2685	0.4702	0.3397	CCNA2/FOXO1/CFLAR	3
BP	GO:0072176	nephric duct development	3/2112	16/18670	0.2685	0.4702	0.3397	BMP4/PKD2/AHI1	3
BP	GO:0090036	regulation of protein kinase C signaling	3/2112	16/18670	0.2685	0.4702	0.3397	CD40/AKAP12/GPD1L	3
BP	GO:0090083	regulation of inclusion body assembly	3/2112	16/18670	0.2685	0.4702	0.3397	CLU/SNCAIP/BAG5	3
BP	GO:1902004	positive regulation of amyloid-beta formation	3/2112	16/18670	0.2685	0.4702	0.3397	CLU/ABCG1/IFNG	3
BP	GO:1902992	negative regulation of amyloid precursor protein catabolic process	3/2112	16/18670	0.2685	0.4702	0.3397	IGF1/CLU/SPON1	3
BP	GO:1905153	regulation of membrane invagination	3/2112	16/18670	0.2685	0.4702	0.3397	CD36/GATA2/NCKAP1L	3
BP	GO:2001224	positive regulation of neuron migration	3/2112	16/18670	0.2685	0.4702	0.3397	SEMA3A/NIPBL/KIF20B	3
BP	GO:0042866	pyruvate biosynthetic process	16/2112	119/18670	0.269	0.4708	0.3402	IGF1/ZBTB20/SLC2A6/CBFA2T3/NUP93/HDAC4/HK3/ALDOC/TPR/NUP160/HTR2A/IFNG/ARNT/NUP88/NUP50/TP53	16
BP	GO:0006691	leukotriene metabolic process	5/2112	31/18670	0.2697	0.4708	0.3402	LTC4S/TLR2/SYK/MAPKAPK2/ALOX5	5
BP	GO:0010458	exit from mitosis	5/2112	31/18670	0.2697	0.4708	0.3402	CDKN1C/SIRT7/UBE2C/CDC14B/RPL24	5
BP	GO:0032786	positive regulation of DNA-templated transcription, elongation	5/2112	31/18670	0.2697	0.4708	0.3402	CCNT1/BRD4/GTF2F1/PAF1/THOC1	5
BP	GO:0042168	heme metabolic process	5/2112	31/18670	0.2697	0.4708	0.3402	NFE2L1/ALAS1/BDH2/HMBS/ALAD	5
BP	GO:0050849	negative regulation of calcium-mediated signaling	5/2112	31/18670	0.2697	0.4708	0.3402	SRI/PLEK/PKD2/GSTO1/GSTM2	5
BP	GO:0060292	long-term synaptic depression	5/2112	31/18670	0.2697	0.4708	0.3402	LILRB2/PLK2/STXBP1/CD38/ABHD6	5
BP	GO:0071539	protein localization to centrosome	5/2112	31/18670	0.2697	0.4708	0.3402	MCPH1/SNX10/GOLGB1/AURKA/STIL	5
BP	GO:0086011	membrane repolarization during action potential	5/2112	31/18670	0.2697	0.4708	0.3402	CACNA2D1/KCNJ5/KCNJ2/ATP1B1/KCNJ8	5
BP	GO:0097106	postsynaptic density organization	5/2112	31/18670	0.2697	0.4708	0.3402	LILRB2/PTPRD/NLGN1/CDH2/PTPRS	5
BP	GO:1902186	regulation of viral release from host cell	5/2112	31/18670	0.2697	0.4708	0.3402	PC/TRIM21/CHMP2B/TRIM26/PML	5
BP	GO:0006457	protein folding	29/2112	227/18670	0.2703	0.4717	0.3408	CLU/CD74/GAK/CRYAB/SPHK1/HSPA6/CRTAP/BAG2/HSPA4L/FKBP5/EMC2/VCP/NKTR/HSP90AB1/DNAJC7/PPIC/PEX19/HSPB1/RIC3/CDC37L1/HSPB6/PPIG/VBP1/EMC6/HSPA1L/BAG5/DNAJB4/DNAJC2/ST13	29
BP	GO:0035601	protein deacylation	14/2112	103/18670	0.2732	0.4767	0.3444	SKI/SIRT7/HDAC4/PRKD2/PER2/IFNG/MSL3/BEX4/NIPBL/PINK1/MORF4L1/PRKD1/TP53/TBL1X	14
BP	GO:1902115	regulation of organelle assembly	25/2112	194/18670	0.2739	0.4778	0.3452	LCP1/DYNC2LI1/MAP4/PTPRD/PLK1/PIP4K2B/DZIP1/TPR/CEP135/STAG2/PTPRS/PLK2/FEZ1/STX18/ATG3/PINK1/AKAP13/CHMP2B/PIP4K2A/HCK/ATXN2/FEZ2/GSN/CHMP1B/STIL	25
BP	GO:0051651	maintenance of location in cell	13/2112	95/18670	0.2752	0.4792	0.3462	ASPM/SRI/SKP1/TMSB10/SRGN/DAG1/BARD1/GPAA1/KDELR3/KDELR2/PINK1/GSN/PML	13
BP	GO:0008207	C21-steroid hormone metabolic process	6/2112	39/18670	0.2756	0.4792	0.3462	AKR1C3/AKR1B1/AKR1C1/DHRS9/CYP46A1/DKK3	6
BP	GO:0009072	aromatic amino acid family metabolic process	6/2112	39/18670	0.2756	0.4792	0.3462	FAH/IDO1/KYNU/PCBD1/HPD/KMO	6
BP	GO:0032692	negative regulation of interleukin-1 production	6/2112	39/18670	0.2756	0.4792	0.3462	TNFAIP3/IGF1/CX3CR1/SERPINB1/PML/NLRP3	6
BP	GO:0035886	vascular smooth muscle cell differentiation	6/2112	39/18670	0.2756	0.4792	0.3462	SGCB/COMP/DNMT1/NOTCH1/HEY2/FGF9	6
BP	GO:0038179	neurotrophin signaling pathway	6/2112	39/18670	0.2756	0.4792	0.3462	CORO1A/NDN/NTRK2/MAGI2/CYFIP2/PTPN11	6
BP	GO:0042769	DNA damage response, detection of DNA damage	6/2112	39/18670	0.2756	0.4792	0.3462	DTL/NEK1/UBE2B/RFC3/PARP1/CUL4B	6
BP	GO:0043001	Golgi to plasma membrane protein transport	6/2112	39/18670	0.2756	0.4792	0.3462	CSK/PREPL/BBS1/VAMP2/GOLGA7/SPTBN1	6
BP	GO:0045684	positive regulation of epidermis development	6/2112	39/18670	0.2756	0.4792	0.3462	BMP4/PRKCH/FOXC1/NOTCH1/FST/KRT10	6
BP	GO:0051180	vitamin transport	6/2112	39/18670	0.2756	0.4792	0.3462	SLC2A6/CD320/SLC23A2/AFM/LMBRD1/SLC5A6	6
BP	GO:0060306	regulation of membrane repolarization	6/2112	39/18670	0.2756	0.4792	0.3462	CACNA2D1/ANK2/KCNJ2/SCN1B/WDR1/SNTA1	6
BP	GO:0010970	transport along microtubule	21/2112	161/18670	0.2767	0.4806	0.3473	UCHL1/RASGRP1/DYNC2LI1/MREG/PURA/TRAK2/KIF3B/KIF4A/DYNC1I1/SOD1/CLUAP1/FEZ1/TRIM58/HSPB1/MAP1B/SYBU/DYNLRB1/ARL3/FYCO1/KIF1B/KIF23	21
BP	GO:0018393	internal peptidyl-lysine acetylation	21/2112	161/18670	0.2767	0.4806	0.3473	NAP1L2/ING3/IRF4/AUTS2/BAZ1A/GATA2/CREBBP/KMT2A/TAF7/RPS6KA4/LEF1/EID1/MECP2/MSL3/MBIP/KAT6B/SPI1/PHF10/RSF1/MORF4L1/IL1B	21
BP	GO:0099111	microtubule-based transport	21/2112	161/18670	0.2767	0.4806	0.3473	UCHL1/RASGRP1/DYNC2LI1/MREG/PURA/TRAK2/KIF3B/KIF4A/DYNC1I1/SOD1/CLUAP1/FEZ1/TRIM58/HSPB1/MAP1B/SYBU/DYNLRB1/ARL3/FYCO1/KIF1B/KIF23	21
BP	GO:0032984	protein-containing complex disassembly	41/2112	329/18670	0.2773	0.4816	0.3479	LRP6/GABARAPL1/ADD3/TMOD1/GAK/CKAP2/GABARAPL2/KIF18B/FGF13/SMARCD3/PLEK/ASPH/KIF2C/VPS16/DSTN/SMARCC2/VCP/LMOD1/PPP1CA/DHX8/MICAL1/SMARCD1/ZFAND1/CAMSAP2/MAP1B/MRPL15/MRPS14/CHMP2B/CFL1/CAPZA1/VILL/HMGA1/DVL1/WDR1/FYCO1/FZD2/FRAT1/SPTBN1/GSN/CHMP1B/MRPL20	41
BP	GO:0034763	negative regulation of transmembrane transport	17/2112	128/18670	0.2777	0.4821	0.3483	ENPP1/PID1/SRI/PRKCB/DYSF/GEM/PLN/ARL6IP5/LEP/ATP1A2/FABP5/CRBN/PKD2/GSTO1/KCNAB1/GSTM2/IL1B	17
BP	GO:0031110	regulation of microtubule polymerization or depolymerization	11/2112	79/18670	0.2783	0.4829	0.3489	MAPRE2/CKAP2/FGF13/TUBB4A/MECP2/TERF1/PAK1/CAMSAP2/MAP1B/CLIP3/CDH5	11
BP	GO:0055072	iron ion homeostasis	11/2112	79/18670	0.2783	0.4829	0.3489	SRI/SKP1/SLC22A17/CYBRD1/CP/TFRC/NEO1/SOD1/BDH2/HFE/NDFIP1	11
BP	GO:0002832	negative regulation of response to biotic stimulus	7/2112	47/18670	0.2786	0.4829	0.3489	TNFAIP3/HTRA1/MICB/TSPAN6/TRIM38/SPINK5/IL2RA	7
BP	GO:0031952	regulation of protein autophosphorylation	7/2112	47/18670	0.2786	0.4829	0.3489	ENPP1/PTPRC/PDGFD/TOM1L1/ADIPOQ/GFRA2/MVP	7
BP	GO:0045023	G0 to G1 transition	7/2112	47/18670	0.2786	0.4829	0.3489	TFDP2/RRM2/HLA-G/EZH2/CDC7/SUZ12/APAF1	7
BP	GO:0060351	cartilage development involved in endochondral bone morphogenesis	7/2112	47/18670	0.2786	0.4829	0.3489	SCARA3/SOX9/COCH/COMP/SHOX2/COL14A1/HOXA11	7
BP	GO:0001541	ovarian follicle development	8/2112	55/18670	0.2798	0.4848	0.3503	KITLG/FOXC1/INHBA/ICAM1/SOD1/FOXO3/ANG/PTX3	8
BP	GO:0006120	mitochondrial electron transport, NADH to ubiquinone	8/2112	55/18670	0.2798	0.4848	0.3503	NDUFC1/NDUFS2/NDUFS4/NDUFA13/PINK1/NDUFA9/NDUFB6/NDUFA4	8
BP	GO:0046530	photoreceptor cell differentiation	9/2112	63/18670	0.28	0.485	0.3504	SOX9/NTRK2/PTN/NOTCH1/DIO3/ARL3/ROM1/NPHP4/AHI1	9
BP	GO:1903052	positive regulation of proteolysis involved in cellular protein catabolic process	16/2112	120/18670	0.2803	0.4853	0.3507	CLU/CBFA2T3/CTSC/PLK1/CHFR/BAG2/EDEM1/PLK2/VCP/RGN/RNF19B/CEBPA/DVL1/EDEM2/AURKA/RNF14	16
BP	GO:0042303	molting cycle	15/2112	112/18670	0.2829	0.4896	0.3537	IGFBP5/SOX9/INHBA/FGF7/EGFR/FA2H/TP63/NOTCH1/ARNTL/NIPBL/FZD6/FST/FERMT1/SPINK5/KRT33B	15
BP	GO:0042633	hair cycle	15/2112	112/18670	0.2829	0.4896	0.3537	IGFBP5/SOX9/INHBA/FGF7/EGFR/FA2H/TP63/NOTCH1/ARNTL/NIPBL/FZD6/FST/FERMT1/SPINK5/KRT33B	15
BP	GO:0001919	regulation of receptor recycling	4/2112	24/18670	0.285	0.4908	0.3546	TBC1D16/TRAT1/KIF16B/AP1AR	4
BP	GO:0002861	regulation of inflammatory response to antigenic stimulus	4/2112	24/18670	0.285	0.4908	0.3546	CCR7/HLA-E/BTK/CD81	4
BP	GO:0006862	nucleotide transport	4/2112	24/18670	0.285	0.4908	0.3546	SLC25A36/SLC25A4/SLC25A23/SLC25A5	4
BP	GO:0009218	pyrimidine ribonucleotide metabolic process	4/2112	24/18670	0.285	0.4908	0.3546	UPP1/NME7/ENTPD4/NME4	4
BP	GO:0021871	forebrain regionalization	4/2112	24/18670	0.285	0.4908	0.3546	BMP4/GLI3/EMX2/FEZF2	4
BP	GO:0021904	dorsal/ventral neural tube patterning	4/2112	24/18670	0.285	0.4908	0.3546	BMP4/GLI3/TCTN1/TULP3	4
BP	GO:0032878	regulation of establishment or maintenance of cell polarity	4/2112	24/18670	0.285	0.4908	0.3546	KANK1/KIF20B/GSN/CDH5	4
BP	GO:0034162	toll-like receptor 9 signaling pathway	4/2112	24/18670	0.285	0.4908	0.3546	TLR8/MYD88/TNIP2/PTPRS	4
BP	GO:0034505	tooth mineralization	4/2112	24/18670	0.285	0.4908	0.3546	TCIRG1/FOXO1/TFAP2A/ALPL	4
BP	GO:0036315	cellular response to sterol	4/2112	24/18670	0.285	0.4908	0.3546	LRP6/INHBA/NFE2L1/DAG1	4
BP	GO:0044062	regulation of excretion	4/2112	24/18670	0.285	0.4908	0.3546	TAC1/SNX5/AGTR1/EDNRB	4
BP	GO:0045603	positive regulation of endothelial cell differentiation	4/2112	24/18670	0.285	0.4908	0.3546	BMP4/TMEM100/NOTCH1/CDH5	4
BP	GO:0045606	positive regulation of epidermal cell differentiation	4/2112	24/18670	0.285	0.4908	0.3546	BMP4/PRKCH/FOXC1/NOTCH1	4
BP	GO:0046475	glycerophospholipid catabolic process	4/2112	24/18670	0.285	0.4908	0.3546	PNPLA6/PLA2G4C/PRDX6/LIPC	4
BP	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process	4/2112	24/18670	0.285	0.4908	0.3546	ENPP1/SLC26A2/TPST1/BPNT1	4
BP	GO:1901071	glucosamine-containing compound metabolic process	4/2112	24/18670	0.285	0.4908	0.3546	EXTL2/CHST3/NAGK/OVGP1	4
BP	GO:1905564	positive regulation of vascular endothelial cell proliferation	4/2112	24/18670	0.285	0.4908	0.3546	ITGA4/FGF2/SP1/AKT3	4
BP	GO:0006892	post-Golgi vesicle-mediated transport	14/2112	104/18670	0.2855	0.4913	0.355	CSK/PREPL/GAK/TRIM23/KIF16B/STX4/BBS1/VAMP2/AP1AR/ARL3/GOLGA7/VTI1B/RAB14/SPTBN1	14
BP	GO:0098732	macromolecule deacylation	14/2112	104/18670	0.2855	0.4913	0.355	SKI/SIRT7/HDAC4/PRKD2/PER2/IFNG/MSL3/BEX4/NIPBL/PINK1/MORF4L1/PRKD1/TP53/TBL1X	14
BP	GO:1901800	positive regulation of proteasomal protein catabolic process	14/2112	104/18670	0.2855	0.4913	0.355	CLU/CBFA2T3/PLK1/CHFR/BAG2/EDEM1/PLK2/VCP/RNF19B/CEBPA/DVL1/EDEM2/AURKA/RNF14	14
BP	GO:0035637	multicellular organismal signaling	26/2112	204/18670	0.2883	0.496	0.3584	TYMP/SRI/NTRK2/CACNA2D1/ANK2/KCNK1/JAM3/NPR2/FXYD1/FXYD6/KCNJ5/AHCYL1/PLN/ASPH/SOD1/KCNJ2/TRPC1/ATP1B1/SCN1B/DSC2/ATP1A2/SLC8A1/RYR3/GJC1/S1PR1/ATP2A3	26
BP	GO:0003206	cardiac chamber morphogenesis	17/2112	129/18670	0.2887	0.4964	0.3586	BMP4/FOXC1/ZFPM2/BMPR1A/SHOX2/DHRS3/TGFBR3/SMARCD3/PARVA/CPE/RBP4/NOTCH1/HEY2/ACVR1/HEY1/FZD2/TP53	17
BP	GO:0006639	acylglycerol metabolic process	17/2112	129/18670	0.2887	0.4964	0.3586	GK/PLCE1/SIK1/PCK1/PTPN11/LIPG/RGN/DGKA/FABP5/CETP/NR1H3/FABP4/ABHD6/ANG/SLC27A5/CAT/LIPC	17
BP	GO:0051099	positive regulation of binding	23/2112	179/18670	0.2894	0.4975	0.3595	BMP4/IGF1/FOXC1/SKI/PPP2CA/IRF4/JAK2/RIPK2/SPON1/EIF3E/LARP6/TCF7L2/PPP2CB/PLK2/IFNG/HSP90AB1/DACT1/PARP1/HFE/CRBN/NIPBL/RB1/HIPK2	23
BP	GO:0043506	regulation of JUN kinase activity	12/2112	88/18670	0.2903	0.4989	0.3605	SFRP1/CCL19/MAP3K11/RIPK2/MAP4K1/CD40LG/FZD4/MAP3K2/PAK1/SYK/PTPN22/TLR6	12
BP	GO:0009416	response to light stimulus	39/2112	314/18670	0.2907	0.4995	0.3609	PIK3R1/SCARA3/DTL/MFAP4/MEIS2/EGFR/UBE2B/CREBBP/OPN3/SLC1A3/SIK1/BAK1/PER2/PTN/MAPK13/FEN1/HYAL1/HRH1/PPP1CA/ATP1A2/MECP2/CCND1/PARP1/ELOVL4/PER3/AURKB/SDF4/GUCA1A/METAP2/CUL4B/CAT/DYNLRB1/ERCC1/PBK/TP53/PLEKHB1/NPHP4/PML/B4GALT2	39
BP	GO:0043462	regulation of ATPase activity	11/2112	80/18670	0.2925	0.4999	0.3612	PFN2/GABARAPL2/NCAPH/PLN/ATP1B1/TOR1AIP1/RGN/PLSCR1/DNAJB4/SETMAR/PFN1	11
BP	GO:0003338	metanephros morphogenesis	5/2112	32/18670	0.2925	0.4999	0.3612	BMP4/STAT1/SOX9/SIX2/PKD2	5
BP	GO:0006739	NADP metabolic process	5/2112	32/18670	0.2925	0.4999	0.3612	FMO2/IDH2/RPIA/PGD/TALDO1	5
BP	GO:0032228	regulation of synaptic transmission, GABAergic	5/2112	32/18670	0.2925	0.4999	0.3612	USP46/TAC1/NLGN1/CA2/STXBP1	5
BP	GO:0035510	DNA dealkylation	5/2112	32/18670	0.2925	0.4999	0.3612	FTO/APOBEC3G/APOBEC3B/ASCC1/USP7	5
BP	GO:0039694	viral RNA genome replication	5/2112	32/18670	0.2925	0.4999	0.3612	APOBEC3G/CXCL8/TOP2A/FBXL2/MPHOSPH8	5
BP	GO:0045907	positive regulation of vasoconstriction	5/2112	32/18670	0.2925	0.4999	0.3612	ICAM1/EGFR/HTR2A/HRH1/CD38	5
BP	GO:0045922	negative regulation of fatty acid metabolic process	5/2112	32/18670	0.2925	0.4999	0.3612	ACADVL/ERLIN1/ACACB/ERLIN2/ACADL	5
BP	GO:0046039	GTP metabolic process	5/2112	32/18670	0.2925	0.4999	0.3612	AMPD3/NME7/MOCS2/MBIP/NME4	5
BP	GO:0048741	skeletal muscle fiber development	5/2112	32/18670	0.2925	0.4999	0.3612	SKI/PPP3CA/SIX1/HDAC4/SHOX2	5
BP	GO:0055022	negative regulation of cardiac muscle tissue growth	5/2112	32/18670	0.2925	0.4999	0.3612	MEIS1/KCNK2/RBP4/PAK1/JARID2	5
BP	GO:0061117	negative regulation of heart growth	5/2112	32/18670	0.2925	0.4999	0.3612	MEIS1/KCNK2/RBP4/PAK1/JARID2	5
BP	GO:0070207	protein homotrimerization	5/2112	32/18670	0.2925	0.4999	0.3612	CD247/SKI/SIGMAR1/HLA-G/ATXN10	5
BP	GO:0070570	regulation of neuron projection regeneration	5/2112	32/18670	0.2925	0.4999	0.3612	HGF/SCARF1/PTPRF/PTN/PTPRS	5
BP	GO:0086019	cell-cell signaling involved in cardiac conduction	5/2112	32/18670	0.2925	0.4999	0.3612	CACNA2D1/ANK2/KCNJ5/SCN1B/GJC1	5
BP	GO:0099623	regulation of cardiac muscle cell membrane repolarization	5/2112	32/18670	0.2925	0.4999	0.3612	CACNA2D1/ANK2/SCN1B/WDR1/SNTA1	5
BP	GO:1901976	regulation of cell cycle checkpoint	5/2112	32/18670	0.2925	0.4999	0.3612	NDC80/MAD2L1/TPR/CCNB1/THOC1	5
BP	GO:1905508	protein localization to microtubule organizing center	5/2112	32/18670	0.2925	0.4999	0.3612	MCPH1/SNX10/GOLGB1/AURKA/STIL	5
BP	GO:2000778	positive regulation of interleukin-6 secretion	5/2112	32/18670	0.2925	0.4999	0.3612	TLR8/LGALS9/IFIH1/DDX58/IL1B	5
BP	GO:0009206	purine ribonucleoside triphosphate biosynthetic process	22/2112	171/18670	0.2928	0.5003	0.3615	PID1/IGF1/ZBTB20/SLC2A6/CBFA2T3/NUP93/HDAC4/HK3/NME7/ALDOC/TPR/NUP160/HTR2A/VCP/IFNG/ARNT/PARP1/PINK1/NME4/NUP88/NUP50/TP53	22
BP	GO:0006305	DNA alkylation	10/2112	72/18670	0.2944	0.5026	0.3631	KMT2A/EZH2/DNMT1/ATRX/PIK3CA/MECP2/MPHOSPH8/RLF/PARP1/SPI1	10
BP	GO:0006306	DNA methylation	10/2112	72/18670	0.2944	0.5026	0.3631	KMT2A/EZH2/DNMT1/ATRX/PIK3CA/MECP2/MPHOSPH8/RLF/PARP1/SPI1	10
BP	GO:0050805	negative regulation of synaptic transmission	10/2112	72/18670	0.2944	0.5026	0.3631	LILRB2/PCDH17/HTR2A/PLK2/ADIPOQ/STXBP1/CD38/ABHD6/MTMR2/IL1B	10
BP	GO:0071548	response to dexamethasone	6/2112	40/18670	0.296	0.5039	0.3641	ICAM1/EGFR/PCK1/FOXO1/FOXO3/CFLAR	6
BP	GO:0072210	metanephric nephron development	6/2112	40/18670	0.296	0.5039	0.3641	BMP4/STAT1/SOX9/SIX2/ADIPOQ/PKD2	6
BP	GO:0090184	positive regulation of kidney development	6/2112	40/18670	0.296	0.5039	0.3641	BMP4/SOX9/SIX1/PDGFD/ADIPOQ/CFLAR	6
BP	GO:0098760	response to interleukin-7	6/2112	40/18670	0.296	0.5039	0.3641	IL2RG/IL7R/SOCS1/CISH/SOCS2/BTK	6
BP	GO:0098761	cellular response to interleukin-7	6/2112	40/18670	0.296	0.5039	0.3641	IL2RG/IL7R/SOCS1/CISH/SOCS2/BTK	6
BP	GO:0010257	NADH dehydrogenase complex assembly	9/2112	64/18670	0.296	0.5039	0.3641	NDUFC1/NDUFS2/NDUFS4/NDUFA13/NDUFAF3/NUBPL/NDUFA9/ECSIT/NDUFB6	9
BP	GO:0016445	somatic diversification of immunoglobulins	9/2112	64/18670	0.296	0.5039	0.3641	PTPRC/IL27RA/BATF/CD40/TFRC/TBX21/CD40LG/ERCC1/THOC1	9
BP	GO:0032981	mitochondrial respiratory chain complex I assembly	9/2112	64/18670	0.296	0.5039	0.3641	NDUFC1/NDUFS2/NDUFS4/NDUFA13/NDUFAF3/NUBPL/NDUFA9/ECSIT/NDUFB6	9
BP	GO:0043297	apical junction assembly	9/2112	64/18670	0.296	0.5039	0.3641	PRKCH/DLG5/PARD3/ECT2/PECAM1/MYO1C/MPP5/WDR1/NPHP4	9
BP	GO:2000378	negative regulation of reactive oxygen species metabolic process	9/2112	64/18670	0.296	0.5039	0.3641	CRYAB/SLC18A2/RGN/TFAP2A/PINK1/HP/GLA/CFLAR/TP53	9
BP	GO:0008038	neuron recognition	7/2112	48/18670	0.2971	0.5053	0.3651	EPHA3/CXCR4/NDN/SEMA3A/MEGF8/CRTAC1/FEZF2	7
BP	GO:0009311	oligosaccharide metabolic process	7/2112	48/18670	0.2971	0.5053	0.3651	B3GALNT1/GAL3ST4/IDUA/GLA/MAN2B1/FUT8/MANBA	7
BP	GO:0021517	ventral spinal cord development	7/2112	48/18670	0.2971	0.5053	0.3651	HOXC10/GLI3/NFE2L1/GATA2/TCTN1/HOXD10/GDPD5	7
BP	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	7/2112	48/18670	0.2971	0.5053	0.3651	BTC/PTPN2/EGFR/GPRC5A/HBEGF/ZGPAT/SNX5	7
BP	GO:0070613	regulation of protein processing	23/2112	180/18670	0.2989	0.506	0.3656	GAS1/BIRC3/CLU/CST7/ADAM8/CFP/PROS1/SPON1/CR1/BAG2/GLG1/CD19/IGLC1/IGLV1-44/C7/IGHG1/CFB/CD81/RFX4/GSN/IL1B/CR2/C6	23
BP	GO:0006638	neutral lipid metabolic process	17/2112	130/18670	0.2998	0.506	0.3656	GK/PLCE1/SIK1/PCK1/PTPN11/LIPG/RGN/DGKA/FABP5/CETP/NR1H3/FABP4/ABHD6/ANG/SLC27A5/CAT/LIPC	17
BP	GO:0000097	sulfur amino acid biosynthetic process	3/2112	17/18670	0.3009	0.506	0.3656	BHMT2/CDO1/CBS	3
BP	GO:0006089	lactate metabolic process	3/2112	17/18670	0.3009	0.506	0.3656	PER2/HAGH/TP53	3
BP	GO:0006586	indolalkylamine metabolic process	3/2112	17/18670	0.3009	0.506	0.3656	IDO1/KYNU/KMO	3
BP	GO:0006590	thyroid hormone generation	3/2112	17/18670	0.3009	0.506	0.3656	DIO2/CPQ/DIO3	3
BP	GO:0006895	Golgi to endosome transport	3/2112	17/18670	0.3009	0.506	0.3656	KIF16B/AP1AR/RAB14	3
BP	GO:0007379	segment specification	3/2112	17/18670	0.3009	0.506	0.3656	COBL/MEOX1/MTF2	3
BP	GO:0008340	determination of adult lifespan	3/2112	17/18670	0.3009	0.506	0.3656	LEP/INPP5D/TP53	3
BP	GO:0009070	serine family amino acid biosynthetic process	3/2112	17/18670	0.3009	0.506	0.3656	SERINC3/CBS/PSPH	3
BP	GO:0010715	regulation of extracellular matrix disassembly	3/2112	17/18670	0.3009	0.506	0.3656	DDR2/PDPN/IL6	3
BP	GO:0015693	magnesium ion transport	3/2112	17/18670	0.3009	0.506	0.3656	MAGT1/KCNJ2/CNNM2	3
BP	GO:0015732	prostaglandin transport	3/2112	17/18670	0.3009	0.506	0.3656	ABCC4/LEP/IL1B	3
BP	GO:0015868	purine ribonucleotide transport	3/2112	17/18670	0.3009	0.506	0.3656	SLC25A4/SLC25A23/SLC25A5	3
BP	GO:0016254	preassembly of GPI anchor in ER membrane	3/2112	17/18670	0.3009	0.506	0.3656	PIGH/PIGP/PIGF	3
BP	GO:0016584	nucleosome positioning	3/2112	17/18670	0.3009	0.506	0.3656	SMARCA1/PAF1/RSF1	3
BP	GO:0030011	maintenance of cell polarity	3/2112	17/18670	0.3009	0.506	0.3656	DLG5/NCKAP1L/WDR1	3
BP	GO:0031000	response to caffeine	3/2112	17/18670	0.3009	0.506	0.3656	SLC8A1/RYR3/GSTM2	3
BP	GO:0031268	pseudopodium organization	3/2112	17/18670	0.3009	0.506	0.3656	CCR7/CCL21/CDC42EP3	3
BP	GO:0032460	negative regulation of protein oligomerization	3/2112	17/18670	0.3009	0.506	0.3656	CLU/CRYAB/CRBN	3
BP	GO:0035988	chondrocyte proliferation	3/2112	17/18670	0.3009	0.506	0.3656	DDR2/SIX2/COMP	3
BP	GO:0036270	response to diuretic	3/2112	17/18670	0.3009	0.506	0.3656	SLC8A1/RYR3/GSTM2	3
BP	GO:0042249	establishment of planar polarity of embryonic epithelium	3/2112	17/18670	0.3009	0.506	0.3656	SFRP1/DVL1/FZD2	3
BP	GO:0043651	linoleic acid metabolic process	3/2112	17/18670	0.3009	0.506	0.3656	ELOVL2/GSTM2/ELOVL5	3
BP	GO:0043968	histone H2A acetylation	3/2112	17/18670	0.3009	0.506	0.3656	ING3/MSL3/MORF4L1	3
BP	GO:0045721	negative regulation of gluconeogenesis	3/2112	17/18670	0.3009	0.506	0.3656	SIK1/FAM3C/ADIPOQ	3
BP	GO:0050665	hydrogen peroxide biosynthetic process	3/2112	17/18670	0.3009	0.506	0.3656	SOD1/MAOB/CYBA	3
BP	GO:0061298	retina vasculature development in camera-type eye	3/2112	17/18670	0.3009	0.506	0.3656	LRP5/FZD4/ROM1	3
BP	GO:0061318	renal filtration cell differentiation	3/2112	17/18670	0.3009	0.506	0.3656	BMP4/MAGI2/ADIPOQ	3
BP	GO:0062033	positive regulation of mitotic sister chromatid segregation	3/2112	17/18670	0.3009	0.506	0.3656	DLGAP5/NIPBL/RB1	3
BP	GO:0070131	positive regulation of mitochondrial translation	3/2112	17/18670	0.3009	0.506	0.3656	NGRN/RMND1/UQCC1	3
BP	GO:0071360	cellular response to exogenous dsRNA	3/2112	17/18670	0.3009	0.506	0.3656	IFIH1/DDX58/COLEC12	3
BP	GO:0072112	glomerular visceral epithelial cell differentiation	3/2112	17/18670	0.3009	0.506	0.3656	BMP4/MAGI2/ADIPOQ	3
BP	GO:0090185	negative regulation of kidney development	3/2112	17/18670	0.3009	0.506	0.3656	BMP4/STAT1/ADIPOQ	3
BP	GO:0097329	response to antimetabolite	3/2112	17/18670	0.3009	0.506	0.3656	BLM/ATRX/TIMELESS	3
BP	GO:1900363	regulation of mRNA polyadenylation	3/2112	17/18670	0.3009	0.506	0.3656	CPEB1/CPSF6/CCNT1	3
BP	GO:1902683	regulation of receptor localization to synapse	3/2112	17/18670	0.3009	0.506	0.3656	DAG1/GPC4/ADAM10	3
BP	GO:1903209	positive regulation of oxidative stress-induced cell death	3/2112	17/18670	0.3009	0.506	0.3656	SOD1/FOXO3/TLR6	3
BP	GO:1904948	midbrain dopaminergic neuron differentiation	3/2112	17/18670	0.3009	0.506	0.3656	SFRP1/LRP6/RYK	3
BP	GO:1905331	negative regulation of morphogenesis of an epithelium	3/2112	17/18670	0.3009	0.506	0.3656	BMP4/STAT1/SULF1	3
BP	GO:0042775	mitochondrial ATP synthesis coupled electron transport	13/2112	97/18670	0.3009	0.506	0.3656	NDUFC1/BID/NDUFS2/NDUFS4/CDK1/NDUFA13/CCNB1/MECP2/PINK1/NDUFA9/SDHA/NDUFB6/NDUFA4	13
BP	GO:0006094	gluconeogenesis	12/2112	89/18670	0.3039	0.5107	0.369	PTPN2/ALDOC/PC/SIK1/PCK1/PER2/FAM3C/FOXO1/RBP4/LEP/ADIPOQ/MDH1	12
BP	GO:0006497	protein lipidation	12/2112	89/18670	0.3039	0.5107	0.369	PIGK/DPM3/GPAA1/PIGH/ZDHHC18/PIGP/CLIP3/PIGT/GOLGA7/PIGF/UGCG/ZDHHC14	12
BP	GO:0061053	somite development	12/2112	89/18670	0.3039	0.5107	0.369	SFRP1/LRP6/FOXC1/SIX1/BMPR1A/COBL/MEOX1/LEF1/SMAD3/NOTCH1/NLE1/TP53	12
BP	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	11/2112	81/18670	0.3068	0.5127	0.3705	SKI/HTRA1/ADAMTSL2/TGFBR3/GLG1/CHST11/PMEPA1/SMAD3/LDLRAD4/TGFB3/TP53	11
BP	GO:0032204	regulation of telomere maintenance	11/2112	81/18670	0.3068	0.5127	0.3705	PRKCQ/NEK7/NEK2/ATRX/TERF1/PARP1/AURKB/ERCC1/USP7/PARN/PML	11
BP	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	11/2112	81/18670	0.3068	0.5127	0.3705	CLU/CBFA2T3/PLK1/CHFR/PLK2/VCP/RNF19B/CEBPA/DVL1/AURKA/RNF14	11
BP	GO:0008543	fibroblast growth factor receptor signaling pathway	15/2112	114/18670	0.3069	0.5127	0.3705	RBFOX2/FGF18/FGF7/SULF1/PRKD2/FGF2/PTPN11/KL/GTF2F1/KIF16B/POLR2L/FGF9/FAT4/SHCBP1/RAB14	15
BP	GO:0010632	regulation of epithelial cell migration	36/2112	291/18670	0.3088	0.5127	0.3705	CXCL13/BMP4/SEMA4A/FGF18/SOX9/SEMA3A/EMP2/ANGPT1/FGF7/PFN2/MAPRE2/ITGB1BP1/CD40/PRKD2/ANXA3/GATA2/HBEGF/FGF2/DCN/TAC1/SP1/PTN/DOCK1/HYAL1/PLK2/NOTCH1/IFNG/MECP2/PPM1F/HSPB1/AKT3/PRKD1/KDR/CAPN7/PFN1/CTSH	36
BP	GO:0033555	multicellular organismal response to stress	10/2112	73/18670	0.3096	0.5127	0.3705	PENK/GCH1/IDO1/PPP3CA/USP46/THBS4/TAC1/MECP2/EDNRB/BRINP1	10
BP	GO:1901983	regulation of protein acetylation	10/2112	73/18670	0.3096	0.5127	0.3705	NAP1L2/AUTS2/GATA2/KMT2A/TAF7/RPS6KA4/ARNTL/EID1/SPI1/IL1B	10
BP	GO:0007041	lysosomal transport	14/2112	106/18670	0.3104	0.5127	0.3705	CLU/GAK/TRAK2/NPC1/PCDHGA3/HOOK2/VPS16/GPRASP1/VCP/PINK1/SCARB2/DENND3/CHMP2B/USE1	14
BP	GO:0000729	DNA double-strand break processing	4/2112	25/18670	0.3116	0.5127	0.3705	BLM/BARD1/RNF138/SETMAR	4
BP	GO:0001945	lymph vessel development	4/2112	25/18670	0.3116	0.5127	0.3705	PTPN14/FOXC1/PDPN/SYK	4
BP	GO:0006851	mitochondrial calcium ion transmembrane transport	4/2112	25/18670	0.3116	0.5127	0.3705	YME1L1/AFG3L2/MICU1/SLC25A23	4
BP	GO:0007026	negative regulation of microtubule depolymerization	4/2112	25/18670	0.3116	0.5127	0.3705	CKAP2/FGF13/CAMSAP2/MAP1B	4
BP	GO:0031069	hair follicle morphogenesis	4/2112	25/18670	0.3116	0.5127	0.3705	IGFBP5/FGF7/TP63/NOTCH1	4
BP	GO:0032509	endosome transport via multivesicular body sorting pathway	4/2112	25/18670	0.3116	0.5127	0.3705	VPS37C/VCP/CHMP2B/CHMP1B	4
BP	GO:0034035	purine ribonucleoside bisphosphate metabolic process	4/2112	25/18670	0.3116	0.5127	0.3705	ENPP1/SLC26A2/TPST1/BPNT1	4
BP	GO:0043951	negative regulation of cAMP-mediated signaling	4/2112	25/18670	0.3116	0.5127	0.3705	LPAR1/UBE2B/APLNR/PDE3B	4
BP	GO:0044247	cellular polysaccharide catabolic process	4/2112	25/18670	0.3116	0.5127	0.3705	PHKB/PPP1CA/AOAH/MANBA	4
BP	GO:0045830	positive regulation of isotype switching	4/2112	25/18670	0.3116	0.5127	0.3705	PTPRC/CD40/TFRC/TBX21	4
BP	GO:0051307	meiotic chromosome separation	4/2112	25/18670	0.3116	0.5127	0.3705	NCAPH/TOP2A/RMI1/TTK	4
BP	GO:0051560	mitochondrial calcium ion homeostasis	4/2112	25/18670	0.3116	0.5127	0.3705	AFG3L2/MICU1/SLC25A23/TGM2	4
BP	GO:0061217	regulation of mesonephros development	4/2112	25/18670	0.3116	0.5127	0.3705	BMP4/SOX9/SIX1/SIX2	4
BP	GO:1904861	excitatory synapse assembly	4/2112	25/18670	0.3116	0.5127	0.3705	SEMA4A/PTPRD/NLGN1/PTPRS	4
BP	GO:1905809	negative regulation of synapse organization	4/2112	25/18670	0.3116	0.5127	0.3705	LILRB2/TLR2/NLGN1/PTN	4
BP	GO:0045739	positive regulation of DNA repair	9/2112	65/18670	0.3122	0.5127	0.3705	EYA4/EYA2/EGFR/WAS/TIMELESS/PARP1/SETMAR/SMCHD1/ACTR2	9
BP	GO:0048663	neuron fate commitment	9/2112	65/18670	0.3122	0.5127	0.3705	BMP4/BCL11B/HOXC10/GLI3/SIX1/GATA2/NOTCH1/HOXD10/FEZF2	9
BP	GO:0042773	ATP synthesis coupled electron transport	13/2112	98/18670	0.3141	0.5127	0.3705	NDUFC1/BID/NDUFS2/NDUFS4/CDK1/NDUFA13/CCNB1/MECP2/PINK1/NDUFA9/SDHA/NDUFB6/NDUFA4	13
BP	GO:0018208	peptidyl-proline modification	8/2112	57/18670	0.3143	0.5127	0.3705	CRTAP/FKBP5/P4HTM/NKTR/FKBP14/PPIC/PPIG/FKBP10	8
BP	GO:0019320	hexose catabolic process	8/2112	57/18670	0.3143	0.5127	0.3705	GALT/HK3/ALDOC/LRP5/FUT8/TP53/TKTL1/FUT4	8
BP	GO:0043525	positive regulation of neuron apoptotic process	8/2112	57/18670	0.3143	0.5127	0.3705	NQO1/MAP3K11/HDAC4/TFAP2A/BACE1/DDIT3/FOXO3/TP53	8
BP	GO:0050819	negative regulation of coagulation	8/2112	57/18670	0.3143	0.5127	0.3705	PROS1/PROCR/PLAT/CD9/PRKG1/TFPI/SH2B3/GP1BA	8
BP	GO:0000012	single strand break repair	2/2112	10/18670	0.315	0.5127	0.3705	TDP1/PARP1	2
BP	GO:0001660	fever generation	2/2112	10/18670	0.315	0.5127	0.3705	EDNRB/IL1B	2
BP	GO:0003149	membranous septum morphogenesis	2/2112	10/18670	0.315	0.5127	0.3705	BMP4/FZD2	2
BP	GO:0003211	cardiac ventricle formation	2/2112	10/18670	0.315	0.5127	0.3705	SMARCD3/NOTCH1	2
BP	GO:0006228	UTP biosynthetic process	2/2112	10/18670	0.315	0.5127	0.3705	NME7/NME4	2
BP	GO:0006307	DNA dealkylation involved in DNA repair	2/2112	10/18670	0.315	0.5127	0.3705	FTO/ASCC1	2
BP	GO:0006570	tyrosine metabolic process	2/2112	10/18670	0.315	0.5127	0.3705	FAH/HPD	2
BP	GO:0006930	substrate-dependent cell migration, cell extension	2/2112	10/18670	0.315	0.5127	0.3705	MYH10/CTTN	2
BP	GO:0007028	cytoplasm organization	2/2112	10/18670	0.315	0.5127	0.3705	ETV6/FOSL1	2
BP	GO:0007220	Notch receptor processing	2/2112	10/18670	0.315	0.5127	0.3705	GALNT11/ADAM10	2
BP	GO:0007440	foregut morphogenesis	2/2112	10/18670	0.315	0.5127	0.3705	SMAD3/NOTCH1	2
BP	GO:0008343	adult feeding behavior	2/2112	10/18670	0.315	0.5127	0.3705	USP46/LEP	2
BP	GO:0010739	positive regulation of protein kinase A signaling	2/2112	10/18670	0.315	0.5127	0.3705	AKAP12/ADIPOQ	2
BP	GO:0010918	positive regulation of mitochondrial membrane potential	2/2112	10/18670	0.315	0.5127	0.3705	BID/VCP	2
BP	GO:0014041	regulation of neuron maturation	2/2112	10/18670	0.315	0.5127	0.3705	EDNRB/BCL11A	2
BP	GO:0014049	positive regulation of glutamate secretion	2/2112	10/18670	0.315	0.5127	0.3705	KMO/STXBP1	2
BP	GO:0016102	diterpenoid biosynthetic process	2/2112	10/18670	0.315	0.5127	0.3705	AKR1C3/DHRS9	2
BP	GO:0018065	protein-cofactor linkage	2/2112	10/18670	0.315	0.5127	0.3705	HMBS/LIPT1	2
BP	GO:0030388	fructose 1,6-bisphosphate metabolic process	2/2112	10/18670	0.315	0.5127	0.3705	ALDOC/IFNG	2
BP	GO:0032464	positive regulation of protein homooligomerization	2/2112	10/18670	0.315	0.5127	0.3705	CLU/BID	2
BP	GO:0032621	interleukin-18 production	2/2112	10/18670	0.315	0.5127	0.3705	TLR2/NLRP3	2
BP	GO:0033210	leptin-mediated signaling pathway	2/2112	10/18670	0.315	0.5127	0.3705	LEP/UGCG	2
BP	GO:0033314	mitotic DNA replication checkpoint	2/2112	10/18670	0.315	0.5127	0.3705	NAE1/TOPBP1	2
BP	GO:0034058	endosomal vesicle fusion	2/2112	10/18670	0.315	0.5127	0.3705	SPHK1/SAMD9	2
BP	GO:0034085	establishment of sister chromatid cohesion	2/2112	10/18670	0.315	0.5127	0.3705	NIPBL/RB1	2
BP	GO:0035376	sterol import	2/2112	10/18670	0.315	0.5127	0.3705	CD36/STARD5	2
BP	GO:0035845	photoreceptor cell outer segment organization	2/2112	10/18670	0.315	0.5127	0.3705	NPHP4/AHI1	2
BP	GO:0035871	protein K11-linked deubiquitination	2/2112	10/18670	0.315	0.5127	0.3705	TNFAIP3/VCPIP1	2
BP	GO:0035878	nail development	2/2112	10/18670	0.315	0.5127	0.3705	FZD6/PRKAB1	2
BP	GO:0035999	tetrahydrofolate interconversion	2/2112	10/18670	0.315	0.5127	0.3705	MTHFD2/TYMS	2
BP	GO:0036500	ATF6-mediated unfolded protein response	2/2112	10/18670	0.315	0.5127	0.3705	DDIT3/MBTPS2	2
BP	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway	2/2112	10/18670	0.315	0.5127	0.3705	DDR2/SYK	2
BP	GO:0042989	sequestering of actin monomers	2/2112	10/18670	0.315	0.5127	0.3705	TMSB10/GSN	2
BP	GO:0043084	penile erection	2/2112	10/18670	0.315	0.5127	0.3705	ADA/EDNRB	2
BP	GO:0043471	regulation of cellular carbohydrate catabolic process	2/2112	10/18670	0.315	0.5127	0.3705	PPP1CA/SCARB2	2
BP	GO:0044351	macropinocytosis	2/2112	10/18670	0.315	0.5127	0.3705	DOCK2/MAPKAPK2	2
BP	GO:0044359	modulation of molecular function in other organism	2/2112	10/18670	0.315	0.5127	0.3705	NUCKS1/PTX3	2
BP	GO:0044803	multi-organism membrane organization	2/2112	10/18670	0.315	0.5127	0.3705	CCR5/CXCR4	2
BP	GO:0045348	positive regulation of MHC class II biosynthetic process	2/2112	10/18670	0.315	0.5127	0.3705	JAK2/IFNG	2
BP	GO:0045657	positive regulation of monocyte differentiation	2/2112	10/18670	0.315	0.5127	0.3705	CD74/ZFP36L1	2
BP	GO:0045713	low-density lipoprotein particle receptor biosynthetic process	2/2112	10/18670	0.315	0.5127	0.3705	ADIPOQ/ITGAV	2
BP	GO:0045876	positive regulation of sister chromatid cohesion	2/2112	10/18670	0.315	0.5127	0.3705	FEN1/NIPBL	2
BP	GO:0045945	positive regulation of transcription by RNA polymerase III	2/2112	10/18670	0.315	0.5127	0.3705	AR/CEBPA	2
BP	GO:0045988	negative regulation of striated muscle contraction	2/2112	10/18670	0.315	0.5127	0.3705	SRI/ATP1A2	2
BP	GO:0046498	S-adenosylhomocysteine metabolic process	2/2112	10/18670	0.315	0.5127	0.3705	AHCYL1/AHCYL2	2
BP	GO:0048382	mesendoderm development	2/2112	10/18670	0.315	0.5127	0.3705	BMPR1A/ZFP36L1	2
BP	GO:0048703	embryonic viscerocranium morphogenesis	2/2112	10/18670	0.315	0.5127	0.3705	CHST11/NIPBL	2
BP	GO:0048755	branching morphogenesis of a nerve	2/2112	10/18670	0.315	0.5127	0.3705	SHOX2/BCL11A	2
BP	GO:0051593	response to folic acid	2/2112	10/18670	0.315	0.5127	0.3705	TYMS/GSN	2
BP	GO:0052205	modulation of molecular function in other organism involved in symbiotic interaction	2/2112	10/18670	0.315	0.5127	0.3705	NUCKS1/PTX3	2
BP	GO:0060600	dichotomous subdivision of an epithelial terminal unit	2/2112	10/18670	0.315	0.5127	0.3705	SEMA3A/CTSH	2
BP	GO:0061140	lung secretory cell differentiation	2/2112	10/18670	0.315	0.5127	0.3705	NFIB/HOXA5	2
BP	GO:0061299	retina vasculature morphogenesis in camera-type eye	2/2112	10/18670	0.315	0.5127	0.3705	LRP5/FZD4	2
BP	GO:0070099	regulation of chemokine-mediated signaling pathway	2/2112	10/18670	0.315	0.5127	0.3705	CCL5/SH2B3	2
BP	GO:0070508	cholesterol import	2/2112	10/18670	0.315	0.5127	0.3705	CD36/STARD5	2
BP	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain	2/2112	10/18670	0.315	0.5127	0.3705	BRD4/GTF2H5	2
BP	GO:0070862	negative regulation of protein exit from endoplasmic reticulum	2/2112	10/18670	0.315	0.5127	0.3705	UBE2J1/UBE2G2	2
BP	GO:0071104	response to interleukin-9	2/2112	10/18670	0.315	0.5127	0.3705	IL2RG/STAT1	2
BP	GO:0071501	cellular response to sterol depletion	2/2112	10/18670	0.315	0.5127	0.3705	ERLIN1/ERLIN2	2
BP	GO:0072531	pyrimidine-containing compound transmembrane transport	2/2112	10/18670	0.315	0.5127	0.3705	AQP9/SLC25A36	2
BP	GO:0086070	SA node cell to atrial cardiac muscle cell communication	2/2112	10/18670	0.315	0.5127	0.3705	ANK2/GJC1	2
BP	GO:0090309	positive regulation of methylation-dependent chromatin silencing	2/2112	10/18670	0.315	0.5127	0.3705	DNMT1/MPHOSPH8	2
BP	GO:0090557	establishment of endothelial intestinal barrier	2/2112	10/18670	0.315	0.5127	0.3705	ICAM1/PTPRS	2
BP	GO:0097050	type B pancreatic cell apoptotic process	2/2112	10/18670	0.315	0.5127	0.3705	TCF7L2/IL6	2
BP	GO:0097105	presynaptic membrane assembly	2/2112	10/18670	0.315	0.5127	0.3705	PTPRD/NLGN1	2
BP	GO:0097278	complement-dependent cytotoxicity	2/2112	10/18670	0.315	0.5127	0.3705	RAB27A/HSP90AB1	2
BP	GO:0106049	regulation of cellular response to osmotic stress	2/2112	10/18670	0.315	0.5127	0.3705	MICU1/SLC25A23	2
BP	GO:0150011	regulation of neuron projection arborization	2/2112	10/18670	0.315	0.5127	0.3705	FZD4/DVL1	2
BP	GO:1900222	negative regulation of amyloid-beta clearance	2/2112	10/18670	0.315	0.5127	0.3705	LRPAP1/IFNG	2
BP	GO:1901033	positive regulation of response to reactive oxygen species	2/2112	10/18670	0.315	0.5127	0.3705	RGN/FOXO3	2
BP	GO:1902033	regulation of hematopoietic stem cell proliferation	2/2112	10/18670	0.315	0.5127	0.3705	KITLG/PIM1	2
BP	GO:1902101	positive regulation of metaphase/anaphase transition of cell cycle	2/2112	10/18670	0.315	0.5127	0.3705	DLGAP5/RB1	2
BP	GO:1902513	regulation of organelle transport along microtubule	2/2112	10/18670	0.315	0.5127	0.3705	FEZ1/TRIM58	2
BP	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway	2/2112	10/18670	0.315	0.5127	0.3705	CASP1/CASP4	2
BP	GO:1903332	regulation of protein folding	2/2112	10/18670	0.315	0.5127	0.3705	BAG5/ST13	2
BP	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA	2/2112	10/18670	0.315	0.5127	0.3705	PPP3CA/TP53	2
BP	GO:1904526	regulation of microtubule binding	2/2112	10/18670	0.315	0.5127	0.3705	PPP2CA/PPP2CB	2
BP	GO:1904684	negative regulation of metalloendopeptidase activity	2/2112	10/18670	0.315	0.5127	0.3705	TIMP3/RECK	2
BP	GO:1904896	ESCRT complex disassembly	2/2112	10/18670	0.315	0.5127	0.3705	CHMP2B/CHMP1B	2
BP	GO:1904903	ESCRT III complex disassembly	2/2112	10/18670	0.315	0.5127	0.3705	CHMP2B/CHMP1B	2
BP	GO:2000035	regulation of stem cell division	2/2112	10/18670	0.315	0.5127	0.3705	NAP1L2/EVI2B	2
BP	GO:2000317	negative regulation of T-helper 17 type immune response	2/2112	10/18670	0.315	0.5127	0.3705	IL27RA/TBX21	2
BP	GO:2000644	regulation of receptor catabolic process	2/2112	10/18670	0.315	0.5127	0.3705	MYLIP/MTMR2	2
BP	GO:2000849	regulation of glucocorticoid secretion	2/2112	10/18670	0.315	0.5127	0.3705	TAC1/PTPN11	2
BP	GO:2001054	negative regulation of mesenchymal cell apoptotic process	2/2112	10/18670	0.315	0.5127	0.3705	GDF5/SOX9	2
BP	GO:2001214	positive regulation of vasculogenesis	2/2112	10/18670	0.315	0.5127	0.3705	TMEM100/KDR	2
BP	GO:2001225	regulation of chloride transport	2/2112	10/18670	0.315	0.5127	0.3705	CA2/PRKG2	2
BP	GO:0099003	vesicle-mediated transport in synapse	26/2112	207/18670	0.3151	0.5127	0.3705	PREPL/RAB8A/PRKCB/PFN2/GAK/USP46/ITSN1/DNM1/DENND1A/NLGN1/CLSTN1/TMEM230/HTR2A/CHRNA5/RAB27A/SYT17/STX4/VAMP2/STXBP1/PINK1/BACE1/DVL1/STX6/CASK/P2RY4/CADPS	26
BP	GO:0006471	protein ADP-ribosylation	5/2112	33/18670	0.3157	0.5127	0.3705	PARP12/IFNG/PARP4/PARP1/PARP8	5
BP	GO:0009303	rRNA transcription	5/2112	33/18670	0.3157	0.5127	0.3705	SIRT7/NPM3/ANG/TP53/SPIN1	5
BP	GO:0019934	cGMP-mediated signaling	5/2112	33/18670	0.3157	0.5127	0.3705	NPR2/CD36/HTR2B/EDNRB/PRKG1	5
BP	GO:0040001	establishment of mitotic spindle localization	5/2112	33/18670	0.3157	0.5127	0.3705	NUSAP1/NDC80/MAD2L1/PLK1/MCPH1	5
BP	GO:0051194	positive regulation of cofactor metabolic process	5/2112	33/18670	0.3157	0.5127	0.3705	IGF1/ZBTB20/HTR2A/IFNG/ARNT	5
BP	GO:0060603	mammary gland duct morphogenesis	5/2112	33/18670	0.3157	0.5127	0.3705	LRP6/AR/ETV5/LRP5/PML	5
BP	GO:0071985	multivesicular body sorting pathway	5/2112	33/18670	0.3157	0.5127	0.3705	RAB27A/VPS37C/VCP/CHMP2B/CHMP1B	5
BP	GO:0099084	postsynaptic specialization organization	5/2112	33/18670	0.3157	0.5127	0.3705	LILRB2/PTPRD/NLGN1/CDH2/PTPRS	5
BP	GO:0003254	regulation of membrane depolarization	7/2112	49/18670	0.3159	0.5127	0.3705	DCN/FHL1/SCN1B/MYOC/PARP1/KDR/GPD1L	7
BP	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	7/2112	49/18670	0.3159	0.5127	0.3705	TNFAIP3/STAT1/RHOH/ZMYND11/ADIPOQ/TNIP3/USP10	7
BP	GO:0071715	icosanoid transport	7/2112	49/18670	0.3159	0.5127	0.3705	PLA2G2D/ABCC4/NMB/PLA2G12A/LEP/SYK/IL1B	7
BP	GO:1901571	fatty acid derivative transport	7/2112	49/18670	0.3159	0.5127	0.3705	PLA2G2D/ABCC4/NMB/PLA2G12A/LEP/SYK/IL1B	7
BP	GO:0050954	sensory perception of mechanical stimulus	21/2112	165/18670	0.3165	0.5129	0.3706	ALDH7A1/EYA4/CXCR4/SIX1/ICAM1/COCH/SOBP/SLC1A3/SOD1/FZD4/HTR2A/ZNF354A/NAV2/PIEZO2/TFAP2A/CLIC5/NIPBL/BACE1/MYO3A/WDR1/TBL1X	21
BP	GO:2001242	regulation of intrinsic apoptotic signaling pathway	21/2112	165/18670	0.3165	0.5129	0.3706	LCK/S100A9/CLU/BCL2A1/SERINC3/CD74/BID/PTPN2/ACKR3/NDUFA13/SOD1/BCL2L2/PMAIP1/PARP1/HSPB1/PINK1/SGMS1/IVNS1ABP/DDIT3/BAG5/TP53	21
BP	GO:0006308	DNA catabolic process	6/2112	41/18670	0.3166	0.5129	0.3706	ISG20/ERI3/RGN/APAF1/IL6/SETMAR	6
BP	GO:0034122	negative regulation of toll-like receptor signaling pathway	6/2112	41/18670	0.3166	0.5129	0.3706	TNFAIP3/IRF4/PTPRS/MFHAS1/LYN/TLR6	6
BP	GO:0035337	fatty-acyl-CoA metabolic process	6/2112	41/18670	0.3166	0.5129	0.3706	ACAT1/HSD17B12/ELOVL4/ELOVL2/ACSL5/ELOVL5	6
BP	GO:0045616	regulation of keratinocyte differentiation	6/2112	41/18670	0.3166	0.5129	0.3706	PRKCH/FOXC1/CTSL/TP63/NOTCH1/ZFP36L1	6
BP	GO:0090279	regulation of calcium ion import	6/2112	41/18670	0.3166	0.5129	0.3706	DYSF/TRPV2/PLN/PKD2/CCL2/CASK	6
BP	GO:1903317	regulation of protein maturation	23/2112	182/18670	0.3181	0.5151	0.3722	GAS1/BIRC3/CLU/CST7/ADAM8/CFP/PROS1/SPON1/CR1/BAG2/GLG1/CD19/IGLC1/IGLV1-44/C7/IGHG1/CFB/CD81/RFX4/GSN/IL1B/CR2/C6	23
BP	GO:1905954	positive regulation of lipid localization	11/2112	82/18670	0.3214	0.5203	0.3759	ABCG1/CD36/ATP8A1/TAC1/NFKBIA/ACACB/NFKB1/LIPG/ADIPOQ/NR1H3/IL1B	11
BP	GO:0050905	neuromuscular process	14/2112	107/18670	0.3231	0.523	0.3779	UCHL1/PENK/RBFOX2/GCH1/MYH10/HOXC10/GLRB/COMP/SLC1A3/MECP2/HOXD10/BACE1/DVL1/CAMTA1	14
BP	GO:0005977	glycogen metabolic process	10/2112	74/18670	0.325	0.5255	0.3797	ENPP1/IGF1/PPP1R3C/PASK/PHKB/PER2/IL6ST/PPP1CA/SORBS1/UGP2	10
BP	GO:0032507	maintenance of protein location in cell	10/2112	74/18670	0.325	0.5255	0.3797	SKP1/TMSB10/DAG1/BARD1/GPAA1/KDELR3/KDELR2/PINK1/GSN/PML	10
BP	GO:0043507	positive regulation of JUN kinase activity	10/2112	74/18670	0.325	0.5255	0.3797	CCL19/MAP3K11/RIPK2/MAP4K1/CD40LG/FZD4/MAP3K2/PAK1/SYK/TLR6	10
BP	GO:1903036	positive regulation of response to wounding	10/2112	74/18670	0.325	0.5255	0.3797	CXCR4/CD36/PDPN/HBEGF/CLEC7A/PLEK/SCARF1/PTN/KANK1/MYLK	10
BP	GO:0072527	pyrimidine-containing compound metabolic process	13/2112	99/18670	0.3273	0.5291	0.3823	TYMP/NT5E/UPP1/APOBEC3G/ALDH6A1/APOBEC3B/NME7/TYMS/ENTPD4/NME4/TK2/TK1/TKTL1	13
BP	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	9/2112	66/18670	0.3285	0.5309	0.3836	RAB8A/USP46/DNM1/DAG1/CLSTN1/ADAM22/GPC4/LGI1/ADAM10	9
BP	GO:0006304	DNA modification	15/2112	116/18670	0.3313	0.5352	0.3867	FTO/APOBEC3G/APOBEC3B/KMT2A/EZH2/DNMT1/ATRX/PIK3CA/MECP2/MPHOSPH8/RLF/PARP1/SPI1/ASCC1/USP7	15
BP	GO:2000736	regulation of stem cell differentiation	15/2112	116/18670	0.3313	0.5352	0.3867	PSMB9/BMP4/PSMB8/PSMB10/SOX9/LTBP3/FOXC1/SOX5/YAP1/GATA2/PSME1/KMT2A/PTN/NOTCH1/ZFP36L2	15
BP	GO:0051899	membrane depolarization	12/2112	91/18670	0.3316	0.5352	0.3867	CACNA2D1/ANK2/DCN/FHL1/KCNJ2/SCN1B/MYOC/ATP1A2/SLC8A1/PARP1/KDR/GPD1L	12
BP	GO:0055081	anion homeostasis	8/2112	58/18670	0.3319	0.5352	0.3867	ENPP1/ABCG1/LIPG/SLC12A2/SLC12A8/CETP/RCN3/SLC12A7	8
BP	GO:0003414	chondrocyte morphogenesis involved in endochondral bone morphogenesis	3/2112	18/18670	0.3334	0.5352	0.3867	SCARA3/COCH/COL14A1	3
BP	GO:0003429	growth plate cartilage chondrocyte morphogenesis	3/2112	18/18670	0.3334	0.5352	0.3867	SCARA3/COCH/COL14A1	3
BP	GO:0007194	negative regulation of adenylate cyclase activity	3/2112	18/18670	0.3334	0.5352	0.3867	CCR2/EDNRB/NPR3	3
BP	GO:0009048	dosage compensation by inactivation of X chromosome	3/2112	18/18670	0.3334	0.5352	0.3867	LRIF1/XIST/SMCHD1	3
BP	GO:0009200	deoxyribonucleoside triphosphate metabolic process	3/2112	18/18670	0.3334	0.5352	0.3867	ADK/ADA/TYMS	3
BP	GO:0010878	cholesterol storage	3/2112	18/18670	0.3334	0.5352	0.3867	ABCG1/CD36/NR1H3	3
BP	GO:0015865	purine nucleotide transport	3/2112	18/18670	0.3334	0.5352	0.3867	SLC25A4/SLC25A23/SLC25A5	3
BP	GO:0031293	membrane protein intracellular domain proteolysis	3/2112	18/18670	0.3334	0.5352	0.3867	NFKB1/ADAM10/MBTPS2	3
BP	GO:0031468	nuclear envelope reassembly	3/2112	18/18670	0.3334	0.5352	0.3867	PPP2CA/VRK1/LMNA	3
BP	GO:0032693	negative regulation of interleukin-10 production	3/2112	18/18670	0.3334	0.5352	0.3867	IDO1/PDCD1LG2/LILRB1	3
BP	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter	3/2112	18/18670	0.3334	0.5352	0.3867	BRD4/GTF2F1/PAF1	3
BP	GO:0035994	response to muscle stretch	3/2112	18/18670	0.3334	0.5352	0.3867	NFKBIA/NFKB1/SLC8A1	3
BP	GO:0036166	phenotypic switching	3/2112	18/18670	0.3334	0.5352	0.3867	SP1/DNMT1/FGF9	3
BP	GO:0046459	short-chain fatty acid metabolic process	3/2112	18/18670	0.3334	0.5352	0.3867	PCK1/PCCA/ALDH5A1	3
BP	GO:0048739	cardiac muscle fiber development	3/2112	18/18670	0.3334	0.5352	0.3867	BMP4/SGCD/MYH11	3
BP	GO:0060546	negative regulation of necroptotic process	3/2112	18/18670	0.3334	0.5352	0.3867	BIRC3/SLC25A4/CFLAR	3
BP	GO:0071318	cellular response to ATP	3/2112	18/18670	0.3334	0.5352	0.3867	SOD1/RYR3/P2RY4	3
BP	GO:0072311	glomerular epithelial cell differentiation	3/2112	18/18670	0.3334	0.5352	0.3867	BMP4/MAGI2/ADIPOQ	3
BP	GO:0090171	chondrocyte morphogenesis	3/2112	18/18670	0.3334	0.5352	0.3867	SCARA3/COCH/COL14A1	3
BP	GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	3/2112	18/18670	0.3334	0.5352	0.3867	ZFP36L1/TOB1/ZFP36L2	3
BP	GO:1900221	regulation of amyloid-beta clearance	3/2112	18/18670	0.3334	0.5352	0.3867	CLU/LRPAP1/IFNG	3
BP	GO:2000319	regulation of T-helper 17 cell differentiation	3/2112	18/18670	0.3334	0.5352	0.3867	MALT1/TBX21/NLRP3	3
BP	GO:0001706	endoderm formation	7/2112	50/18670	0.335	0.5371	0.3881	ITGA4/INHBA/ITGB2/COL8A1/SOX2/PAF1/ITGAV	7
BP	GO:0002931	response to ischemia	7/2112	50/18670	0.335	0.5371	0.3881	NDNF/UCHL1/CX3CR1/PER2/PINK1/PANX1/TP53	7
BP	GO:0032873	negative regulation of stress-activated MAPK cascade	7/2112	50/18670	0.335	0.5371	0.3881	SFRP1/FOXO1/ZMYND11/DACT1/PINK1/PTPN22/PBK	7
BP	GO:0070303	negative regulation of stress-activated protein kinase signaling cascade	7/2112	50/18670	0.335	0.5371	0.3881	SFRP1/FOXO1/ZMYND11/DACT1/PINK1/PTPN22/PBK	7
BP	GO:0015696	ammonium transport	14/2112	108/18670	0.336	0.5384	0.389	SLC18A2/ADA/TAF7/HTR2A/SYT17/SLC12A2/SYK/PINK1/BTK/MAOB/SNCG/RALBP1/LYN/LILRB1	14
BP	GO:0008652	cellular amino acid biosynthetic process	11/2112	83/18670	0.336	0.5384	0.389	BHMT2/CDO1/SERINC3/CBS/OAT/SLC1A3/ASPA/NAALAD2/PSPH/FOLH1/AASS	11
BP	GO:0046470	phosphatidylcholine metabolic process	11/2112	83/18670	0.336	0.5384	0.389	PLA2G2D/LPCAT3/CHPT1/PNPLA6/PLA2G12A/PLA2G4C/MECP2/FABP5/CETP/STARD7/LIPC	11
BP	GO:0010470	regulation of gastrulation	6/2112	42/18670	0.3375	0.5401	0.3902	BMPR1A/DAG1/FZD7/ADIPOQ/IL1RN/TENM4	6
BP	GO:0010907	positive regulation of glucose metabolic process	6/2112	42/18670	0.3375	0.5401	0.3902	IGF1/PTPN2/PMAIP1/FOXO1/RGN/SORBS1	6
BP	GO:0015701	bicarbonate transport	6/2112	42/18670	0.3375	0.5401	0.3902	HBB/SLC26A2/CYB5R4/CA14/CYB5R1/CA2	6
BP	GO:0042149	cellular response to glucose starvation	6/2112	42/18670	0.3375	0.5401	0.3902	UPP1/SIK1/PMAIP1/HIGD1A/SESN1/TP53	6
BP	GO:0006516	glycoprotein catabolic process	4/2112	26/18670	0.3385	0.5401	0.3902	EDEM1/EDEM2/MANBA/MMP12	4
BP	GO:0032957	inositol trisphosphate metabolic process	4/2112	26/18670	0.3385	0.5401	0.3902	PLCE1/PLCG2/HRH1/P2RY6	4
BP	GO:0035640	exploration behavior	4/2112	26/18670	0.3385	0.5401	0.3902	PENK/C12orf10/BRINP1/CHL1	4
BP	GO:0036152	phosphatidylethanolamine acyl-chain remodeling	4/2112	26/18670	0.3385	0.5401	0.3902	PLA2G2D/LPCAT3/PLA2G12A/PLA2G4C	4
BP	GO:0043090	amino acid import	4/2112	26/18670	0.3385	0.5401	0.3902	SLC1A3/PER2/ARL6IP5/ATP1A2	4
BP	GO:0045992	negative regulation of embryonic development	4/2112	26/18670	0.3385	0.5401	0.3902	BMP4/SULF1/FZD7/TULP3	4
BP	GO:0055083	monovalent inorganic anion homeostasis	4/2112	26/18670	0.3385	0.5401	0.3902	ENPP1/SLC12A2/SLC12A8/SLC12A7	4
BP	GO:0060037	pharyngeal system development	4/2112	26/18670	0.3385	0.5401	0.3902	BMP4/SIX1/BMPR1A/ACVR1	4
BP	GO:0060669	embryonic placenta morphogenesis	4/2112	26/18670	0.3385	0.5401	0.3902	CDKN1C/SPINT2/LEF1/ZFP36L1	4
BP	GO:0080111	DNA demethylation	4/2112	26/18670	0.3385	0.5401	0.3902	FTO/APOBEC3G/APOBEC3B/USP7	4
BP	GO:1905048	regulation of metallopeptidase activity	4/2112	26/18670	0.3385	0.5401	0.3902	TIMP3/ANTXR1/TIMP2/RECK	4
BP	GO:0006409	tRNA export from nucleus	5/2112	34/18670	0.339	0.5401	0.3902	NUP93/TPR/NUP160/NUP88/NUP50	5
BP	GO:0016601	Rac protein signal transduction	5/2112	34/18670	0.339	0.5401	0.3902	RAC2/AUTS2/RHOG/WASF2/ABI2	5
BP	GO:0032148	activation of protein kinase B activity	5/2112	34/18670	0.339	0.5401	0.3902	IGF1/ITGB1BP1/PINK1/IL18/ANG	5
BP	GO:0032212	positive regulation of telomere maintenance via telomerase	5/2112	34/18670	0.339	0.5401	0.3902	PRKCQ/NEK7/NEK2/AURKB/PARN	5
BP	GO:0042558	pteridine-containing compound metabolic process	5/2112	34/18670	0.339	0.5401	0.3902	GCH1/PCBD1/MTHFD2/TYMS/FOLH1	5
BP	GO:0070050	neuron cellular homeostasis	5/2112	34/18670	0.339	0.5401	0.3902	NELL2/IL6/CHMP2B/FGGY/P2RY4	5
BP	GO:0071431	tRNA-containing ribonucleoprotein complex export from nucleus	5/2112	34/18670	0.339	0.5401	0.3902	NUP93/TPR/NUP160/NUP88/NUP50	5
BP	GO:0001960	negative regulation of cytokine-mediated signaling pathway	10/2112	75/18670	0.3405	0.5418	0.3914	CCL5/PTPRC/PTPN2/ADAR/ADIPOQ/IL6/NR1H3/IL1RN/SH2B3/MMP12	10
BP	GO:0006073	cellular glucan metabolic process	10/2112	75/18670	0.3405	0.5418	0.3914	ENPP1/IGF1/PPP1R3C/PASK/PHKB/PER2/IL6ST/PPP1CA/SORBS1/UGP2	10
BP	GO:0032482	Rab protein signal transduction	10/2112	75/18670	0.3405	0.5418	0.3914	RAB8A/RAB40B/DENND1A/RAB33B/RAB20/RAB27A/GDI1/RAB28/DENND4B/RAB14	10
BP	GO:0044042	glucan metabolic process	10/2112	75/18670	0.3405	0.5418	0.3914	ENPP1/IGF1/PPP1R3C/PASK/PHKB/PER2/IL6ST/PPP1CA/SORBS1/UGP2	10
BP	GO:1903201	regulation of oxidative stress-induced cell death	10/2112	75/18670	0.3405	0.5418	0.3914	OXR1/LANCL1/HGF/SOD1/PARP1/HSPB1/PINK1/FOXO3/BAG5/TLR6	10
BP	GO:0007034	vacuolar transport	18/2112	142/18670	0.3406	0.5419	0.3915	CLU/GAK/TRAK2/NPC1/PCDHGA3/HOOK2/VPS16/VPS37C/GPRASP1/VCP/PINK1/SCARB2/DENND3/CHMP2B/NDFIP1/VTI1B/USE1/CHMP1B	18
BP	GO:0006665	sphingolipid metabolic process	20/2112	159/18670	0.3418	0.5435	0.3927	SERINC3/ALDH3A2/PPP2CA/STS/SGPL1/B3GALNT1/PRKD2/SPHK1/FA2H/SERINC1/SGMS1/ELOVL4/GLA/PRKD1/ELOVL2/UGCG/CERK/ALDH5A1/ELOVL5/CERS4	20
BP	GO:0030858	positive regulation of epithelial cell differentiation	9/2112	67/18670	0.345	0.5484	0.3962	BMP4/PRKCH/SOX9/FOXC1/TMEM100/NOTCH1/ADIPOQ/CDH5/AHI1	9
BP	GO:0043967	histone H4 acetylation	9/2112	67/18670	0.345	0.5484	0.3962	ING3/IRF4/AUTS2/KMT2A/LEF1/MSL3/KAT6B/SPI1/MORF4L1	9
BP	GO:0007006	mitochondrial membrane organization	17/2112	134/18670	0.3456	0.549	0.3967	TFDP2/GZMB/BID/EYA2/TMEM14A/BAK1/AFG3L2/TP63/NDUFA13/APOOL/PMAIP1/PINK1/SLC25A5/TP53BP2/TP53/BNIP3L/MOAP1	17
BP	GO:0018210	peptidyl-threonine modification	17/2112	134/18670	0.3456	0.549	0.3967	GALNT11/VRK2/PARD3/PRKCB/VRK1/PLK1/PRKD2/RIPK2/SPHK1/CDC42BPA/CDK1/CDC7/ACVR1/TTK/NLK/PRKD1/HIPK2	17
BP	GO:2000117	negative regulation of cysteine-type endopeptidase activity	12/2112	92/18670	0.3457	0.549	0.3967	LAMP3/TNFAIP8/BIRC3/CST7/CRYAB/RPS6KA1/HGF/CD27/LEF1/MICAL1/NLE1/CFLAR	12
BP	GO:0008333	endosome to lysosome transport	8/2112	59/18670	0.3496	0.5548	0.4009	TRAK2/PCDHGA3/HOOK2/VPS16/GPRASP1/VCP/DENND3/CHMP2B	8
BP	GO:0032890	regulation of organic acid transport	8/2112	59/18670	0.3496	0.5548	0.4009	PER2/ARL6IP5/LEP/KMO/ATP1A2/SYK/STXBP1/IL1B	8
BP	GO:0046847	filopodium assembly	8/2112	59/18670	0.3496	0.5548	0.4009	CCR7/WASL/CCL21/NLGN1/PPP1R16B/FNBP1L/DPYSL3/TGFB3	8
BP	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	11/2112	84/18670	0.3508	0.5564	0.402	LAMP3/TNFAIP8/BIRC3/CRYAB/RPS6KA1/HGF/CD27/LEF1/MICAL1/NLE1/CFLAR	11
BP	GO:0018107	peptidyl-threonine phosphorylation	16/2112	126/18670	0.3508	0.5564	0.402	VRK2/PARD3/PRKCB/VRK1/PLK1/PRKD2/RIPK2/SPHK1/CDC42BPA/CDK1/CDC7/ACVR1/TTK/NLK/PRKD1/HIPK2	16
BP	GO:0006754	ATP biosynthetic process	20/2112	160/18670	0.3525	0.5564	0.402	PID1/IGF1/ZBTB20/SLC2A6/CBFA2T3/NUP93/HDAC4/HK3/ALDOC/TPR/NUP160/HTR2A/VCP/IFNG/ARNT/PARP1/PINK1/NUP88/NUP50/TP53	20
BP	GO:0007519	skeletal muscle tissue development	20/2112	160/18670	0.3525	0.5564	0.402	HLF/SKI/PPP3CA/CDON/HIVEP3/SIX1/HDAC4/SHOX2/DCN/EPHB1/PITX1/NOTCH1/ARNTL/PAX5/POPDC2/HOXD10/RB1/KCNAB1/CFLAR/MYL6B	20
BP	GO:0009201	ribonucleoside triphosphate biosynthetic process	22/2112	177/18670	0.3525	0.5564	0.402	PID1/IGF1/ZBTB20/SLC2A6/CBFA2T3/NUP93/HDAC4/HK3/NME7/ALDOC/TPR/NUP160/HTR2A/VCP/IFNG/ARNT/PARP1/PINK1/NME4/NUP88/NUP50/TP53	22
BP	GO:0019083	viral transcription	22/2112	177/18670	0.3525	0.5564	0.402	CCL5/NUCKS1/CHD1/RPL31/NUP93/RPL24/TPR/CCNT1/SP1/NUP160/LEF1/TRIM21/GTF2F1/RPS4X/RPL12/POLR2L/RSF1/NUP88/RPL15/NUP50/RPL10A/RPS14	22
BP	GO:2001258	negative regulation of cation channel activity	7/2112	51/18670	0.3541	0.5564	0.402	SRI/DYSF/GEM/PKD2/GSTO1/KCNAB1/GSTM2	7
BP	GO:0045454	cell redox homeostasis	10/2112	76/18670	0.3561	0.5564	0.402	RAC2/SCO2/NCF4/PRDX6/TMX4/DDIT3/CYBA/NCF1/NHLRC2/TXN2	10
BP	GO:0061045	negative regulation of wound healing	10/2112	76/18670	0.3561	0.5564	0.402	PROS1/FGF2/PLAT/SMAD3/CD9/PRKG1/TFPI/SH2B3/GP1BA/CASK	10
BP	GO:0006911	phagocytosis, engulfment	15/2112	118/18670	0.3563	0.5564	0.402	TRBC1/BIN2/ARHGAP25/ITGB2/CD36/GATA2/GULP1/IGHM/IGLL5/DOCK1/NCKAP1L/IGLC1/IGHG1/GSN/ARHGAP12	15
BP	GO:0010324	membrane invagination	17/2112	135/18670	0.3573	0.5564	0.402	TRBC1/BIN2/ARHGAP25/ITGB2/CD36/GATA2/GULP1/IGHM/IGLL5/DOCK1/NCKAP1L/IGLC1/FNBP1L/IGHG1/AURKB/GSN/ARHGAP12	17
BP	GO:0007269	neurotransmitter secretion	21/2112	169/18670	0.3578	0.5564	0.402	PREPL/MCTP1/PRKCB/PFN2/SLC18A2/SNCAIP/NLGN1/HTR2A/CHRNA5/KMO/SYT17/STX4/VAMP2/STXBP1/BACE1/SNCG/NAAA/DVL1/CASK/P2RY4/CADPS	21
BP	GO:0018394	peptidyl-lysine acetylation	21/2112	169/18670	0.3578	0.5564	0.402	NAP1L2/ING3/IRF4/AUTS2/BAZ1A/GATA2/CREBBP/KMT2A/TAF7/RPS6KA4/LEF1/EID1/MECP2/MSL3/MBIP/KAT6B/SPI1/PHF10/RSF1/MORF4L1/IL1B	21
BP	GO:0048489	synaptic vesicle transport	19/2112	152/18670	0.3578	0.5564	0.402	PREPL/PRKCB/PFN2/DNM1/NLGN1/TMEM230/HTR2A/CHRNA5/RAB27A/SYT17/STX4/VAMP2/STXBP1/PINK1/BACE1/DVL1/CASK/P2RY4/CADPS	19
BP	GO:0097480	establishment of synaptic vesicle localization	19/2112	152/18670	0.3578	0.5564	0.402	PREPL/PRKCB/PFN2/DNM1/NLGN1/TMEM230/HTR2A/CHRNA5/RAB27A/SYT17/STX4/VAMP2/STXBP1/PINK1/BACE1/DVL1/CASK/P2RY4/CADPS	19
BP	GO:0001778	plasma membrane repair	2/2112	11/18670	0.3584	0.5564	0.402	MYH10/DYSF	2
BP	GO:0001976	neurological system process involved in regulation of systemic arterial blood pressure	2/2112	11/18670	0.3584	0.5564	0.402	NAV2/MECP2	2
BP	GO:0002328	pro-B cell differentiation	2/2112	11/18670	0.3584	0.5564	0.402	NOTCH1/FLT3	2
BP	GO:0002638	negative regulation of immunoglobulin production	2/2112	11/18670	0.3584	0.5564	0.402	IL13RA2/THOC1	2
BP	GO:0006183	GTP biosynthetic process	2/2112	11/18670	0.3584	0.5564	0.402	NME7/NME4	2
BP	GO:0006620	posttranslational protein targeting to endoplasmic reticulum membrane	2/2112	11/18670	0.3584	0.5564	0.402	SEC62/SEC63	2
BP	GO:0006681	galactosylceramide metabolic process	2/2112	11/18670	0.3584	0.5564	0.402	FA2H/ALDH5A1	2
BP	GO:0007256	activation of JNKK activity	2/2112	11/18670	0.3584	0.5564	0.402	MAP3K11/RIPK2	2
BP	GO:0009151	purine deoxyribonucleotide metabolic process	2/2112	11/18670	0.3584	0.5564	0.402	ADK/ADA	2
BP	GO:0009950	dorsal/ventral axis specification	2/2112	11/18670	0.3584	0.5564	0.402	SFRP1/BMPR1A	2
BP	GO:0010269	response to selenium ion	2/2112	11/18670	0.3584	0.5564	0.402	MAOB/ALAD	2
BP	GO:0014883	transition between fast and slow fiber	2/2112	11/18670	0.3584	0.5564	0.402	PPP3CA/GTF2IRD2B	2
BP	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	2/2112	11/18670	0.3584	0.5564	0.402	EXTL2/EXT2	2
BP	GO:0015791	polyol transport	2/2112	11/18670	0.3584	0.5564	0.402	AQP9/SLC5A3	2
BP	GO:0018095	protein polyglutamylation	2/2112	11/18670	0.3584	0.5564	0.402	TTLL1/TPGS2	2
BP	GO:0021604	cranial nerve structural organization	2/2112	11/18670	0.3584	0.5564	0.402	SEMA3A/SEMA3F	2
BP	GO:0031915	positive regulation of synaptic plasticity	2/2112	11/18670	0.3584	0.5564	0.402	MAP1B/CDC20	2
BP	GO:0032276	regulation of gonadotropin secretion	2/2112	11/18670	0.3584	0.5564	0.402	INHBA/LEP	2
BP	GO:0033235	positive regulation of protein sumoylation	2/2112	11/18670	0.3584	0.5564	0.402	HDAC4/ARNT	2
BP	GO:0033629	negative regulation of cell adhesion mediated by integrin	2/2112	11/18670	0.3584	0.5564	0.402	PTPN11/PDE3B	2
BP	GO:0034115	negative regulation of heterotypic cell-cell adhesion	2/2112	11/18670	0.3584	0.5564	0.402	ADIPOQ/IL1RN	2
BP	GO:0035542	regulation of SNARE complex assembly	2/2112	11/18670	0.3584	0.5564	0.402	VPS16/STXBP1	2
BP	GO:0035933	glucocorticoid secretion	2/2112	11/18670	0.3584	0.5564	0.402	TAC1/PTPN11	2
BP	GO:0040015	negative regulation of multicellular organism growth	2/2112	11/18670	0.3584	0.5564	0.402	PLAC8/SOCS2	2
BP	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity	2/2112	11/18670	0.3584	0.5564	0.402	MICB/CADM1	2
BP	GO:0043129	surfactant homeostasis	2/2112	11/18670	0.3584	0.5564	0.402	RCN3/CTSH	2
BP	GO:0045141	meiotic telomere clustering	2/2112	11/18670	0.3584	0.5564	0.402	UBE2B/TERF1	2
BP	GO:0045793	positive regulation of cell size	2/2112	11/18670	0.3584	0.5564	0.402	HSP90AB1/AKT3	2
BP	GO:0046051	UTP metabolic process	2/2112	11/18670	0.3584	0.5564	0.402	NME7/NME4	2
BP	GO:0046348	amino sugar catabolic process	2/2112	11/18670	0.3584	0.5564	0.402	NAGK/OVGP1	2
BP	GO:0046689	response to mercury ion	2/2112	11/18670	0.3584	0.5564	0.402	AQP9/ALAD	2
BP	GO:0048548	regulation of pinocytosis	2/2112	11/18670	0.3584	0.5564	0.402	AXL/NR1H3	2
BP	GO:0048672	positive regulation of collateral sprouting	2/2112	11/18670	0.3584	0.5564	0.402	SEMA4D/EFNA5	2
BP	GO:0048680	positive regulation of axon regeneration	2/2112	11/18670	0.3584	0.5564	0.402	SCARF1/PTN	2
BP	GO:0048742	regulation of skeletal muscle fiber development	2/2112	11/18670	0.3584	0.5564	0.402	HDAC4/SHOX2	2
BP	GO:0051573	negative regulation of histone H3-K9 methylation	2/2112	11/18670	0.3584	0.5564	0.402	DNMT1/PAX5	2
BP	GO:0051974	negative regulation of telomerase activity	2/2112	11/18670	0.3584	0.5564	0.402	TERF1/TP53	2
BP	GO:0060736	prostate gland growth	2/2112	11/18670	0.3584	0.5564	0.402	SOX9/AR	2
BP	GO:0060856	establishment of blood-brain barrier	2/2112	11/18670	0.3584	0.5564	0.402	MXRA8/RECK	2
BP	GO:0060947	cardiac vascular smooth muscle cell differentiation	2/2112	11/18670	0.3584	0.5564	0.402	NOTCH1/HEY2	2
BP	GO:0070254	mucus secretion	2/2112	11/18670	0.3584	0.5564	0.402	ADA/CYBA	2
BP	GO:0070278	extracellular matrix constituent secretion	2/2112	11/18670	0.3584	0.5564	0.402	TNFRSF1B/NOTCH1	2
BP	GO:0070587	regulation of cell-cell adhesion involved in gastrulation	2/2112	11/18670	0.3584	0.5564	0.402	ADIPOQ/IL1RN	2
BP	GO:0070933	histone H4 deacetylation	2/2112	11/18670	0.3584	0.5564	0.402	SIRT7/HDAC4	2
BP	GO:0072070	loop of Henle development	2/2112	11/18670	0.3584	0.5564	0.402	PKD2/POU3F3	2
BP	GO:0086023	adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process	2/2112	11/18670	0.3584	0.5564	0.402	PLN/AKAP13	2
BP	GO:0090657	telomeric loop disassembly	2/2112	11/18670	0.3584	0.5564	0.402	BLM/TERF1	2
BP	GO:0099151	regulation of postsynaptic density assembly	2/2112	11/18670	0.3584	0.5564	0.402	PTPRD/PTPRS	2
BP	GO:1900003	regulation of serine-type endopeptidase activity	2/2112	11/18670	0.3584	0.5564	0.402	CR1/SPINK5	2
BP	GO:1900115	extracellular regulation of signal transduction	2/2112	11/18670	0.3584	0.5564	0.402	LRPAP1/NBL1	2
BP	GO:1900116	extracellular negative regulation of signal transduction	2/2112	11/18670	0.3584	0.5564	0.402	LRPAP1/NBL1	2
BP	GO:1901077	regulation of relaxation of muscle	2/2112	11/18670	0.3584	0.5564	0.402	SRI/PLN	2
BP	GO:1901678	iron coordination entity transport	2/2112	11/18670	0.3584	0.5564	0.402	FLVCR2/SLC22A17	2
BP	GO:1901894	regulation of calcium-transporting ATPase activity	2/2112	11/18670	0.3584	0.5564	0.402	PLN/RGN	2
BP	GO:1902563	regulation of neutrophil activation	2/2112	11/18670	0.3584	0.5564	0.402	ITGB2/SYK	2
BP	GO:1902571	regulation of serine-type peptidase activity	2/2112	11/18670	0.3584	0.5564	0.402	CR1/SPINK5	2
BP	GO:1903011	negative regulation of bone development	2/2112	11/18670	0.3584	0.5564	0.402	RGN/LILRB1	2
BP	GO:1903441	protein localization to ciliary membrane	2/2112	11/18670	0.3584	0.5564	0.402	BBIP1/ARL3	2
BP	GO:1904396	regulation of neuromuscular junction development	2/2112	11/18670	0.3584	0.5564	0.402	SIX1/PTN	2
BP	GO:1905383	protein localization to presynapse	2/2112	11/18670	0.3584	0.5564	0.402	HSPB1/DVL1	2
BP	GO:1905820	positive regulation of chromosome separation	2/2112	11/18670	0.3584	0.5564	0.402	DLGAP5/RB1	2
BP	GO:2000615	regulation of histone H3-K9 acetylation	2/2112	11/18670	0.3584	0.5564	0.402	NAP1L2/KMT2A	2
BP	GO:2000786	positive regulation of autophagosome assembly	2/2112	11/18670	0.3584	0.5564	0.402	PIP4K2B/PIP4K2A	2
BP	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	2/2112	11/18670	0.3584	0.5564	0.402	INHBA/PPP1CA	2
BP	GO:0000413	protein peptidyl-prolyl isomerization	6/2112	43/18670	0.3585	0.5564	0.402	FKBP5/NKTR/FKBP14/PPIC/PPIG/FKBP10	6
BP	GO:0006692	prostanoid metabolic process	6/2112	43/18670	0.3585	0.5564	0.402	AKR1C3/CD74/HPGDS/FABP5/PTGS1/IL1B	6
BP	GO:0006693	prostaglandin metabolic process	6/2112	43/18670	0.3585	0.5564	0.402	AKR1C3/CD74/HPGDS/FABP5/PTGS1/IL1B	6
BP	GO:0021762	substantia nigra development	6/2112	43/18670	0.3585	0.5564	0.402	PLP1/ZNF148/CASP5/FGF9/MAOB/NDRG2	6
BP	GO:0032881	regulation of polysaccharide metabolic process	6/2112	43/18670	0.3585	0.5564	0.402	ENPP1/IGF1/PASK/NFKB1/PPP1CA/SORBS1	6
BP	GO:0034383	low-density lipoprotein particle clearance	6/2112	43/18670	0.3585	0.5564	0.402	CSK/CD36/NPC1/MYLIP/ADIPOQ/SOAT2	6
BP	GO:0045746	negative regulation of Notch signaling pathway	6/2112	43/18670	0.3585	0.5564	0.402	GATA2/EGFR/NFKBIA/HEY2/HEY1/GDPD5	6
BP	GO:0051293	establishment of spindle localization	6/2112	43/18670	0.3585	0.5564	0.402	NUSAP1/MAP4/NDC80/MAD2L1/PLK1/MCPH1	6
BP	GO:0055026	negative regulation of cardiac muscle tissue development	6/2112	43/18670	0.3585	0.5564	0.402	MEIS1/KCNK2/FZD7/RBP4/PAK1/JARID2	6
BP	GO:0032092	positive regulation of protein binding	12/2112	93/18670	0.3598	0.5583	0.4034	BMP4/PPP2CA/RIPK2/SPON1/TCF7L2/PPP2CB/PLK2/HSP90AB1/DACT1/HFE/CRBN/HIPK2	12
BP	GO:0035914	skeletal muscle cell differentiation	9/2112	68/18670	0.3617	0.5601	0.4047	HLF/CDON/HIVEP3/SIX1/EPHB1/NOTCH1/ARNTL/PAX5/RB1	9
BP	GO:0016101	diterpenoid metabolic process	14/2112	110/18670	0.3619	0.5601	0.4047	GPC5/ALDH3A2/AKR1C3/ADH1C/AKR1B1/EGFR/DHRS3/AKR1C1/RBP4/ADH1B/GPC4/ADH5/DHRS9/RETSAT	14
BP	GO:0033559	unsaturated fatty acid metabolic process	14/2112	110/18670	0.3619	0.5601	0.4047	LTC4S/AKR1C3/CD74/HPGDS/PLA2G4C/FABP5/PTGS1/ELOVL4/ELOVL2/GSTM2/IL1B/EPHX2/ALOX5/ELOVL5	14
BP	GO:0001881	receptor recycling	5/2112	35/18670	0.3625	0.5601	0.4047	TBC1D16/TRAT1/KIF16B/AP1AR/CAMLG	5
BP	GO:0003230	cardiac atrium development	5/2112	35/18670	0.3625	0.5601	0.4047	ANK2/SHOX2/NOTCH1/HEY2/ACVR1	5
BP	GO:0019076	viral release from host cell	5/2112	35/18670	0.3625	0.5601	0.4047	PC/TRIM21/CHMP2B/TRIM26/PML	5
BP	GO:0035890	exit from host	5/2112	35/18670	0.3625	0.5601	0.4047	PC/TRIM21/CHMP2B/TRIM26/PML	5
BP	GO:0035891	exit from host cell	5/2112	35/18670	0.3625	0.5601	0.4047	PC/TRIM21/CHMP2B/TRIM26/PML	5
BP	GO:0051294	establishment of spindle orientation	5/2112	35/18670	0.3625	0.5601	0.4047	MAP4/NDC80/MAD2L1/PLK1/MCPH1	5
BP	GO:0052126	movement in host environment	5/2112	35/18670	0.3625	0.5601	0.4047	PC/TRIM21/CHMP2B/TRIM26/PML	5
BP	GO:0052192	movement in environment of other organism involved in symbiotic interaction	5/2112	35/18670	0.3625	0.5601	0.4047	PC/TRIM21/CHMP2B/TRIM26/PML	5
BP	GO:0070873	regulation of glycogen metabolic process	5/2112	35/18670	0.3625	0.5601	0.4047	ENPP1/IGF1/PASK/PPP1CA/SORBS1	5
BP	GO:0097484	dendrite extension	5/2112	35/18670	0.3625	0.5601	0.4047	CXCR4/AUTS2/CYFIP2/SYT17/BCL11A	5
BP	GO:1901385	regulation of voltage-gated calcium channel activity	5/2112	35/18670	0.3625	0.5601	0.4047	SRI/CACNA2D1/DYSF/GEM/FGF14	5
BP	GO:2000785	regulation of autophagosome assembly	5/2112	35/18670	0.3625	0.5601	0.4047	PIP4K2B/FEZ1/PINK1/PIP4K2A/FEZ2	5
BP	GO:2001257	regulation of cation channel activity	22/2112	178/18670	0.3628	0.5601	0.4047	CCR2/SRI/CACNA2D1/ANK2/DYSF/NETO2/ANXA3/GEM/PLCG2/NLGN1/PLN/SCN1B/IFNG/FGF14/P2RY6/VAMP2/PINK1/PKD2/GSTO1/KCNAB1/GSTM2/CCL2	22
BP	GO:0032368	regulation of lipid transport	16/2112	127/18670	0.363	0.5601	0.4047	ABCG1/ATP8A1/TAC1/NFKBIA/NFKB1/PTPN11/LIPG/LEP/AGTR1/ADIPOQ/SYK/CETP/NR1H3/REN/ITGAV/IL1B	16
BP	GO:0099024	plasma membrane invagination	16/2112	127/18670	0.363	0.5601	0.4047	TRBC1/BIN2/ARHGAP25/ITGB2/CD36/GATA2/GULP1/IGHM/IGLL5/DOCK1/NCKAP1L/IGLC1/IGHG1/AURKB/GSN/ARHGAP12	16
BP	GO:0000272	polysaccharide catabolic process	4/2112	27/18670	0.3654	0.5601	0.4047	PHKB/PPP1CA/AOAH/MANBA	4
BP	GO:0003148	outflow tract septum morphogenesis	4/2112	27/18670	0.3654	0.5601	0.4047	BMP4/ZFPM2/BMPR1A/PARVA	4
BP	GO:0032201	telomere maintenance via semi-conservative replication	4/2112	27/18670	0.3654	0.5601	0.4047	RFC3/FEN1/TERF1/POLE2	4
BP	GO:0036151	phosphatidylcholine acyl-chain remodeling	4/2112	27/18670	0.3654	0.5601	0.4047	PLA2G2D/LPCAT3/PLA2G12A/PLA2G4C	4
BP	GO:0045932	negative regulation of muscle contraction	4/2112	27/18670	0.3654	0.5601	0.4047	SRI/SOD1/ATP1A2/PRKG1	4
BP	GO:0051569	regulation of histone H3-K4 methylation	4/2112	27/18670	0.3654	0.5601	0.4047	AUTS2/KMT2A/DNMT1/GFI1	4
BP	GO:1905208	negative regulation of cardiocyte differentiation	4/2112	27/18670	0.3654	0.5601	0.4047	EGFR/FZD7/HEY2/PAK1	4
BP	GO:0050772	positive regulation of axonogenesis	11/2112	85/18670	0.3657	0.5601	0.4047	SEMA4D/NTRK2/SHOX2/TUBB2B/TRPV2/EFNA5/GDI1/PAK1/CHODL/MAP1B/MEGF8	11
BP	GO:0001832	blastocyst growth	3/2112	19/18670	0.3659	0.5601	0.4047	IGF1/ZPR1/GINS1	3
BP	GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin	3/2112	19/18670	0.3659	0.5601	0.4047	OR51E2/CPA3/REN	3
BP	GO:0003422	growth plate cartilage morphogenesis	3/2112	19/18670	0.3659	0.5601	0.4047	SCARA3/COCH/COL14A1	3
BP	GO:0006044	N-acetylglucosamine metabolic process	3/2112	19/18670	0.3659	0.5601	0.4047	EXTL2/CHST3/NAGK	3
BP	GO:0007096	regulation of exit from mitosis	3/2112	19/18670	0.3659	0.5601	0.4047	CDKN1C/UBE2C/CDC14B	3
BP	GO:0009148	pyrimidine nucleoside triphosphate biosynthetic process	3/2112	19/18670	0.3659	0.5601	0.4047	NME7/TYMS/NME4	3
BP	GO:0010544	negative regulation of platelet activation	3/2112	19/18670	0.3659	0.5601	0.4047	CD9/PRKG1/SH2B3	3
BP	GO:0010985	negative regulation of lipoprotein particle clearance	3/2112	19/18670	0.3659	0.5601	0.4047	CSK/LRPAP1/MYLIP	3
BP	GO:0019184	nonribosomal peptide biosynthetic process	3/2112	19/18670	0.3659	0.5601	0.4047	CNDP2/BDH2/HAGH	3
BP	GO:0030859	polarized epithelial cell differentiation	3/2112	19/18670	0.3659	0.5601	0.4047	DLG5/TP63/AHI1	3
BP	GO:0032026	response to magnesium ion	3/2112	19/18670	0.3659	0.5601	0.4047	TNFRSF11B/CCND1/RYR3	3
BP	GO:0032700	negative regulation of interleukin-17 production	3/2112	19/18670	0.3659	0.5601	0.4047	IL27RA/NCKAP1L/IFNG	3
BP	GO:0033189	response to vitamin A	3/2112	19/18670	0.3659	0.5601	0.4047	MAP1B/TYMS/CAT	3
BP	GO:0034312	diol biosynthetic process	3/2112	19/18670	0.3659	0.5601	0.4047	GCH1/PCBD1/SPHK1	3
BP	GO:0035493	SNARE complex assembly	3/2112	19/18670	0.3659	0.5601	0.4047	VPS16/STX4/STXBP1	3
BP	GO:0036303	lymph vessel morphogenesis	3/2112	19/18670	0.3659	0.5601	0.4047	PTPN14/FOXC1/PDPN	3
BP	GO:0036342	post-anal tail morphogenesis	3/2112	19/18670	0.3659	0.5601	0.4047	CHST11/TP63/DCHS1	3
BP	GO:0046653	tetrahydrofolate metabolic process	3/2112	19/18670	0.3659	0.5601	0.4047	GCH1/MTHFD2/TYMS	3
BP	GO:0051131	chaperone-mediated protein complex assembly	3/2112	19/18670	0.3659	0.5601	0.4047	HOPX/CLU/HSP90AB1	3
BP	GO:0060004	reflex	3/2112	19/18670	0.3659	0.5601	0.4047	GLRB/USP46/AFG3L2	3
BP	GO:0060149	negative regulation of posttranscriptional gene silencing	3/2112	19/18670	0.3659	0.5601	0.4047	PPP3CA/ADAR/TP53	3
BP	GO:0060967	negative regulation of gene silencing by RNA	3/2112	19/18670	0.3659	0.5601	0.4047	PPP3CA/ADAR/TP53	3
BP	GO:0060973	cell migration involved in heart development	3/2112	19/18670	0.3659	0.5601	0.4047	BMP4/DCHS1/NOTCH1	3
BP	GO:0071071	regulation of phospholipid biosynthetic process	3/2112	19/18670	0.3659	0.5601	0.4047	HTR2B/HTR2A/FPR2	3
BP	GO:1901741	positive regulation of myoblast fusion	3/2112	19/18670	0.3659	0.5601	0.4047	CXCL9/IL4R/CD53	3
BP	GO:1902170	cellular response to reactive nitrogen species	3/2112	19/18670	0.3659	0.5601	0.4047	CCNA2/FOXO1/CFLAR	3
BP	GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	3/2112	19/18670	0.3659	0.5601	0.4047	HSPB1/PINK1/BAG5	3
BP	GO:1905939	regulation of gonad development	3/2112	19/18670	0.3659	0.5601	0.4047	SOX9/SEMA3A/ZFPM2	3
BP	GO:0006473	protein acetylation	25/2112	204/18670	0.3664	0.5608	0.4052	NAP1L2/ING3/IRF4/AUTS2/BAZ1A/GATA2/CREBBP/KMT2A/SPHK1/TAF7/PCK1/RPS6KA4/LEF1/FOXO1/ARNTL/EID1/MECP2/MSL3/MBIP/KAT6B/SPI1/PHF10/RSF1/MORF4L1/IL1B	25
BP	GO:0046324	regulation of glucose import	8/2112	60/18670	0.3674	0.5619	0.406	ENPP1/PID1/PIK3R1/IGF1/PTPN11/LEP/ADIPOQ/SORBS1	8
BP	GO:0120193	tight junction organization	8/2112	60/18670	0.3674	0.5619	0.406	PRKCH/PARD3/ECT2/PECAM1/MYO1C/TGFB3/MPP5/NPHP4	8
BP	GO:1902808	positive regulation of cell cycle G1/S phase transition	8/2112	60/18670	0.3674	0.5619	0.406	CCND2/EGFR/CDC45/EZH2/HYAL1/CCND1/PAF1/CUL4B	8
BP	GO:0099643	signal release from synapse	21/2112	170/18670	0.3683	0.5631	0.4068	PREPL/MCTP1/PRKCB/PFN2/SLC18A2/SNCAIP/NLGN1/HTR2A/CHRNA5/KMO/SYT17/STX4/VAMP2/STXBP1/BACE1/SNCG/NAAA/DVL1/CASK/P2RY4/CADPS	21
BP	GO:0016079	synaptic vesicle exocytosis	15/2112	119/18670	0.3688	0.5638	0.4074	PREPL/PRKCB/PFN2/NLGN1/HTR2A/CHRNA5/SYT17/STX4/VAMP2/STXBP1/BACE1/DVL1/CASK/P2RY4/CADPS	15
BP	GO:0045814	negative regulation of gene expression, epigenetic	17/2112	136/18670	0.3691	0.5641	0.4075	UBE2B/CDC45/EZH2/FAM172A/DNMT1/MECP2/MTF2/MSL3/MPHOSPH8/SPI1/SUZ12/HELLS/JARID2/MORF4L1/HMGA1/EZH1/SMCHD1	17
BP	GO:0031397	negative regulation of protein ubiquitination	10/2112	77/18670	0.3719	0.568	0.4104	TNFAIP3/DYSF/MAD2L1/BAG2/PER2/FBXO5/IVNS1ABP/BAG5/CAMLG/ISG15	10
BP	GO:2000779	regulation of double-strand break repair	10/2112	77/18670	0.3719	0.568	0.4104	ZNF365/WAS/PPP4C/TIMELESS/PARP1/RAD51AP1/SETMAR/SMCHD1/ACTR2/PML	10
BP	GO:0016050	vesicle organization	39/2112	325/18670	0.3721	0.5682	0.4105	SERPINA1/TAP1/TAPBP/CORO1A/TAP2/RAB8A/LRMP/DYSF/CTSC/GOLGA2/WASL/DNM1/SRGN/F5/SPHK1/SAMD9/SEC31A/HOOK2/STX16/VPS16/RAB20/RAB27A/VPS37C/FNBP1L/STX4/ANKRD28/FBXO5/STXBP1/SCARB2/CHMP2B/SNX10/STX6/VTI1B/CNIH1/SEC23B/TMCC1/RAB14/VAV3/CHMP1B	39
BP	GO:0006479	protein methylation	22/2112	179/18670	0.373	0.5694	0.4114	AUTS2/KMT2A/EZH2/DNMT1/ATRX/ICMT/BRD4/PAX5/MECP2/MTF2/RLF/GFI1/PAF1/SUZ12/SNRPB/SMYD2/JARID2/LMNA/PRMT1/SETMAR/EZH1/METTL22	22
BP	GO:0008213	protein alkylation	22/2112	179/18670	0.373	0.5694	0.4114	AUTS2/KMT2A/EZH2/DNMT1/ATRX/ICMT/BRD4/PAX5/MECP2/MTF2/RLF/GFI1/PAF1/SUZ12/SNRPB/SMYD2/JARID2/LMNA/PRMT1/SETMAR/EZH1/METTL22	22
BP	GO:2000179	positive regulation of neural precursor cell proliferation	7/2112	52/18670	0.3734	0.5698	0.4117	ASPM/GLI3/CDON/SMARCD3/CX3CR1/NOTCH1/LYN	7
BP	GO:0015718	monocarboxylic acid transport	20/2112	162/18670	0.374	0.5705	0.4122	PLA2G2D/ABCC4/AQP9/CD36/SLC16A4/SLC16A2/AKR1C1/MPC2/NMB/PLA2G12A/ACACB/LEP/STARD5/SYK/MPC1/FABP4/SLC27A5/SLCO1C1/SLC5A6/IL1B	20
BP	GO:0042158	lipoprotein biosynthetic process	12/2112	94/18670	0.3741	0.5705	0.4122	PIGK/DPM3/GPAA1/PIGH/ZDHHC18/PIGP/CLIP3/PIGT/GOLGA7/PIGF/UGCG/ZDHHC14	12
BP	GO:0097164	ammonium ion metabolic process	25/2112	205/18670	0.376	0.5734	0.4143	PLA2G2D/GCH1/ALDH7A1/LPCAT3/AKR1C3/CHPT1/ITGB2/SNCAIP/AKR1B1/PNPLA6/AKR1C1/SPHK1/MAOA/PLA2G12A/PLA2G4C/MECP2/FABP5/CETP/SGMS1/MAOB/STARD7/ACADL/LIPC/AKR7A2/PLA2G7	25
BP	GO:0006937	regulation of muscle contraction	21/2112	171/18670	0.3788	0.5775	0.4173	PLCE1/SRI/ANK2/HDAC4/ADA/SPHK1/FGF13/PLN/SOD1/KCNJ2/ATP1B1/DSC2/ATP1A2/MYL5/SLC8A1/CTTN/PRKG1/HSPB6/MYL9/GSTO1/GSTM2	21
BP	GO:0007019	microtubule depolymerization	6/2112	44/18670	0.3796	0.5778	0.4175	CKAP2/KIF18B/FGF13/KIF2C/CAMSAP2/MAP1B	6
BP	GO:0010828	positive regulation of glucose transmembrane transport	6/2112	44/18670	0.3796	0.5778	0.4175	PIK3R1/IGF1/PTPN11/ADIPOQ/SORBS1/CLIP3	6
BP	GO:0014002	astrocyte development	6/2112	44/18670	0.3796	0.5778	0.4175	PLP1/EGFR/IFNG/IL6/FPR2/IL1B	6
BP	GO:0044331	cell-cell adhesion mediated by cadherin	6/2112	44/18670	0.3796	0.5778	0.4175	CDH19/ADAM19/CDH2/PPM1F/FER/CDH5	6
BP	GO:0045601	regulation of endothelial cell differentiation	6/2112	44/18670	0.3796	0.5778	0.4175	BMP4/TMEM100/NOTCH1/APOLD1/IL1B/CDH5	6
BP	GO:0061001	regulation of dendritic spine morphogenesis	6/2112	44/18670	0.3796	0.5778	0.4175	NLGN1/PDLIM5/CFL1/ADAM10/ABI2/ACTR2	6
BP	GO:0055067	monovalent inorganic cation homeostasis	19/2112	154/18670	0.38	0.5783	0.4178	SLAMF8/TCIRG1/DMXL2/TAC1/KCNJ2/SNX5/RAB20/ATP1B1/CA2/AGTR1/ATP1A2/C7/SLC8A1/SLC12A2/SLC12A8/EDNRB/PDK4/SLC12A7/ATP6V1B2	19
BP	GO:0015711	organic anion transport	57/2112	482/18670	0.3806	0.5789	0.4183	PLA2G2D/SLC17A5/NTRK2/ABCG1/NFE2L1/HBB/ABCC4/SLC2A6/AQP9/NFKBIE/SLC26A2/CD36/SLC16A4/ATP8B2/ATP8A1/ATP9A/PDPN/SLC16A2/AKR1C1/SLC1A3/MPC2/NMB/CYB5R4/SLC25A22/CA14/PER2/PLA2G12A/ACACB/SLC37A1/ARL6IP5/CYB5R1/SLC7A5/CA2/SLC25A4/LEP/STARD5/KMO/ATP1A2/PRAF2/SYK/SLC25A23/CETP/VAMP2/STXBP1/PITPNC1/LRRC8D/SCARB2/MPC1/FABP4/STARD7/SLC25A5/SLC27A5/SLC23A2/SLCO1C1/SLC5A6/SLC35A2/IL1B	57
BP	GO:0001942	hair follicle development	11/2112	86/18670	0.3807	0.5789	0.4183	IGFBP5/SOX9/INHBA/FGF7/EGFR/TP63/NOTCH1/FZD6/FST/FERMT1/SPINK5	11
BP	GO:0042058	regulation of epidermal growth factor receptor signaling pathway	11/2112	86/18670	0.3807	0.5789	0.4183	BTC/RHBDF2/PTPN2/EGFR/GPRC5A/HBEGF/ZGPAT/RHBDF1/SNX5/FER/NCF1	11
BP	GO:0031644	regulation of neurological system process	17/2112	137/18670	0.3809	0.579	0.4183	WASF3/TYMP/TNFRSF1B/CST7/PARD3/CTSC/DAG1/TMEM100/HGF/NLGN1/FABP5/EDNRB/ITGAX/DVL1/TENM4/RNF10/MTMR2	17
BP	GO:0050684	regulation of mRNA processing	17/2112	137/18670	0.3809	0.579	0.4183	RBFOX2/CPEB1/SRPK1/CPSF6/BARD1/CCNT1/SRSF8/AHCYL1/FAM172A/SAP18/WTAP/ZFP36L1/CCNB1/PRDX6/PAF1/KHDRBS3/KHDRBS1	17
BP	GO:0016579	protein deubiquitination	34/2112	283/18670	0.381	0.579	0.4183	TRAF3/PSMB9/TNFAIP3/UCHL1/PSMB8/BIRC3/PSMB10/USP11/AR/USP46/TNIP2/IFIH1/PSME1/USP3/BARD1/CDK1/VCPIP1/CCNA2/NFKBIA/DDX58/TRIM21/ADRM1/SMAD3/UBE2D1/VCP/IKBKG/ACTR8/TNIP3/CDC20/USP10/TP53/USP7/DESI2/NLRP3	34
BP	GO:0043687	post-translational protein modification	43/2112	361/18670	0.3828	0.5816	0.4202	PSMB9/SERPINA1/BMP4/PSMB8/IGFBP5/PENK/APOL1/PSMB10/ZBTB16/DTL/UBXN7/RAB8A/SKP1/MXRA8/CP/SCG2/FBXO21/PSME1/CISH/PRSS23/F5/CRTAP/SOCS2/CDH2/VCAN/ICMT/CHRDL1/SOCS6/FN3K/KLHL9/IL6/CUL2/APLP2/KLHL21/ADAM10/FOLH1/RCN1/CUL4B/FSTL3/FBXL7/NAE1/CCNF/CALU	43
BP	GO:0032370	positive regulation of lipid transport	8/2112	61/18670	0.3853	0.5849	0.4226	ABCG1/ATP8A1/TAC1/NFKBIA/LIPG/ADIPOQ/NR1H3/IL1B	8
BP	GO:0042490	mechanoreceptor differentiation	8/2112	61/18670	0.3853	0.5849	0.4226	BMP4/NTRK2/SOD1/NOTCH1/HEY2/FAT4/FZD2/MYCL	8
BP	GO:0090303	positive regulation of wound healing	8/2112	61/18670	0.3853	0.5849	0.4226	CXCR4/CD36/PDPN/HBEGF/CLEC7A/PLEK/KANK1/MYLK	8
BP	GO:0006007	glucose catabolic process	5/2112	36/18670	0.3859	0.585	0.4227	HK3/ALDOC/LRP5/TP53/TKTL1	5
BP	GO:0006699	bile acid biosynthetic process	5/2112	36/18670	0.3859	0.585	0.4227	ACOX2/OSBPL1A/SLC27A5/CYP46A1/OSBPL9	5
BP	GO:0034390	smooth muscle cell apoptotic process	5/2112	36/18670	0.3859	0.585	0.4227	LRP6/IGF1/PDE1A/DNMT1/IFNG	5
BP	GO:0034391	regulation of smooth muscle cell apoptotic process	5/2112	36/18670	0.3859	0.585	0.4227	LRP6/IGF1/PDE1A/DNMT1/IFNG	5
BP	GO:0051031	tRNA transport	5/2112	36/18670	0.3859	0.585	0.4227	NUP93/TPR/NUP160/NUP88/NUP50	5
BP	GO:0097242	amyloid-beta clearance	5/2112	36/18670	0.3859	0.585	0.4227	CLU/ITGB2/CD36/LRPAP1/IFNG	5
BP	GO:0071482	cellular response to light stimulus	16/2112	129/18670	0.3874	0.5871	0.4242	PIK3R1/MFAP4/CREBBP/OPN3/BAK1/PTN/MAPK13/HYAL1/PARP1/AURKB/GUCA1A/METAP2/CUL4B/ERCC1/PBK/TP53	16
BP	GO:0090398	cellular senescence	10/2112	78/18670	0.3877	0.5872	0.4243	HLA-G/BMPR1A/SMC6/PLK2/ARNTL/FBXO5/AKT3/HMGA1/TP53/PML	10
BP	GO:1903313	positive regulation of mRNA metabolic process	10/2112	78/18670	0.3877	0.5872	0.4243	FTO/CPEB1/ZFP36L1/CCNB1/TOB1/PRDX6/PAF1/ZC3HAV1/ZFP36L2/PRR5L	10
BP	GO:0003279	cardiac septum development	14/2112	112/18670	0.3882	0.5878	0.4247	BMP4/MYH10/ANK2/ZFPM2/BMPR1A/DHRS3/TGFBR3/PARVA/NOTCH1/HEY2/ACVR1/HEY1/FZD2/TP53	14
BP	GO:0044070	regulation of anion transport	12/2112	95/18670	0.3884	0.5879	0.4247	ATP8A1/AHCYL1/PER2/ARL6IP5/CA2/LEP/KMO/ATP1A2/SYK/STXBP1/IL1B/PRKG2	12
BP	GO:0097711	ciliary basal body-plasma membrane docking	12/2112	95/18670	0.3884	0.5879	0.4247	CETN2/PLK1/TUBA4A/CDK1/CEP135/TUBB4A/NEK2/TCTN1/CNTRL/CEP63/NPHP4/AHI1	12
BP	GO:0015931	nucleobase-containing compound transport	29/2112	241/18670	0.3908	0.5906	0.4267	RFTN1/PURA/CETN2/MX2/IGF2BP3/NUP93/SLC29A1/CPSF6/TPR/SLC25A36/NUP160/SLC25A4/ZFP36L1/CETN3/THOC2/MYO1C/SLC25A23/SLC29A2/DDX39A/SLC25A5/NUP88/THOC1/ATXN2/NUP50/KHDRBS1/MVP/SLC35A2/HNRNPA3/THOC6	29
BP	GO:0001958	endochondral ossification	4/2112	28/18670	0.3923	0.5906	0.4267	BMP4/FGF18/FOXC1/ALPL	4
BP	GO:0006760	folic acid-containing compound metabolic process	4/2112	28/18670	0.3923	0.5906	0.4267	GCH1/MTHFD2/TYMS/FOLH1	4
BP	GO:0007205	protein kinase C-activating G protein-coupled receptor signaling pathway	4/2112	28/18670	0.3923	0.5906	0.4267	PARD3/HTR2B/CISH/DGKA	4
BP	GO:0021846	cell proliferation in forebrain	4/2112	28/18670	0.3923	0.5906	0.4267	GLI3/DIXDC1/EMX2/POU3F3	4
BP	GO:0033137	negative regulation of peptidyl-serine phosphorylation	4/2112	28/18670	0.3923	0.5906	0.4267	BAK1/HGF/PPM1F/GPD1L	4
BP	GO:0036075	replacement ossification	4/2112	28/18670	0.3923	0.5906	0.4267	BMP4/FGF18/FOXC1/ALPL	4
BP	GO:0045761	regulation of adenylate cyclase activity	4/2112	28/18670	0.3923	0.5906	0.4267	CCR2/TIMP2/EDNRB/NPR3	4
BP	GO:0048679	regulation of axon regeneration	4/2112	28/18670	0.3923	0.5906	0.4267	SCARF1/PTPRF/PTN/PTPRS	4
BP	GO:0060260	regulation of transcription initiation from RNA polymerase II promoter	4/2112	28/18670	0.3923	0.5906	0.4267	TAF7/HEY2/TP53/THRA	4
BP	GO:0070076	histone lysine demethylation	4/2112	28/18670	0.3923	0.5906	0.4267	UBE2B/JARID2/KDM7A/KDM2A	4
BP	GO:0071168	protein localization to chromatin	4/2112	28/18670	0.3923	0.5906	0.4267	PLK1/EZH2/NIPBL/RB1	4
BP	GO:0086013	membrane repolarization during cardiac muscle cell action potential	4/2112	28/18670	0.3923	0.5906	0.4267	KCNJ5/KCNJ2/ATP1B1/KCNJ8	4
BP	GO:0090383	phagosome acidification	4/2112	28/18670	0.3923	0.5906	0.4267	SLAMF8/TCIRG1/RAB20/ATP6V1B2	4
BP	GO:1902745	positive regulation of lamellipodium organization	4/2112	28/18670	0.3923	0.5906	0.4267	RAC2/AUTS2/HDAC4/WASF2	4
BP	GO:0018205	peptidyl-lysine modification	47/2112	397/18670	0.3924	0.5906	0.4267	NAP1L2/ING3/IRF4/AUTS2/BAZ1A/NUP93/HDAC4/IFIH1/GATA2/CREBBP/KMT2A/TAF7/TPR/EZH2/NUP160/RPS6KA4/LEF1/DNMT1/ATRX/BRD4/PAX5/ARNT/EID1/MECP2/MTF2/MSL3/MBIP/RLF/GFI1/KAT6B/SPI1/SUZ12/PHF10/SMYD2/BCL11A/JARID2/LMNA/RSF1/MORF4L1/NUP88/LIPT1/TGM2/SETMAR/EZH1/NUP50/IL1B/METTL22	47
BP	GO:0000186	activation of MAPKK activity	7/2112	53/18670	0.3927	0.5906	0.4267	BMP4/MAP3K11/JAK2/MAP3K8/RIPK2/EGFR/MAP3K2	7
BP	GO:0007632	visual behavior	7/2112	53/18670	0.3927	0.5906	0.4267	MEIS2/HRH1/ATP1A2/MECP2/DYNLRB1/NPHP4/B4GALT2	7
BP	GO:0030195	negative regulation of blood coagulation	7/2112	53/18670	0.3927	0.5906	0.4267	PROS1/PLAT/CD9/PRKG1/TFPI/SH2B3/GP1BA	7
BP	GO:0060563	neuroepithelial cell differentiation	7/2112	53/18670	0.3927	0.5906	0.4267	TMEM231/CDH2/SOD1/LEF1/NOTCH1/HEY2/MYCL	7
BP	GO:1902475	L-alpha-amino acid transmembrane transport	7/2112	53/18670	0.3927	0.5906	0.4267	SLC1A3/SLC25A22/PER2/ARL6IP5/SLC7A5/ATP1A2/PRAF2	7
BP	GO:0051966	regulation of synaptic transmission, glutamatergic	9/2112	70/18670	0.3952	0.5906	0.4267	CCR2/EGFR/NLGN1/CDH2/HTR2A/KMO/ATP1A2/STXBP1/CCL2	9
BP	GO:0001502	cartilage condensation	3/2112	20/18670	0.398	0.5906	0.4267	MGP/SOX9/THRA	3
BP	GO:0006525	arginine metabolic process	3/2112	20/18670	0.398	0.5906	0.4267	FAH/OAT/DDAH2	3
BP	GO:0007130	synaptonemal complex assembly	3/2112	20/18670	0.398	0.5906	0.4267	STAG3/REC8/TRIP13	3
BP	GO:0007549	dosage compensation	3/2112	20/18670	0.398	0.5906	0.4267	LRIF1/XIST/SMCHD1	3
BP	GO:0007620	copulation	3/2112	20/18670	0.398	0.5906	0.4267	ADA/TAC1/EDNRB	3
BP	GO:0010738	regulation of protein kinase A signaling	3/2112	20/18670	0.398	0.5906	0.4267	AKAP12/ADIPOQ/AKAP1	3
BP	GO:0019370	leukotriene biosynthetic process	3/2112	20/18670	0.398	0.5906	0.4267	LTC4S/SYK/ALOX5	3
BP	GO:0031280	negative regulation of cyclase activity	3/2112	20/18670	0.398	0.5906	0.4267	CCR2/EDNRB/NPR3	3
BP	GO:0032769	negative regulation of monooxygenase activity	3/2112	20/18670	0.398	0.5906	0.4267	NFKB1/GFI1/GLA	3
BP	GO:0039529	RIG-I signaling pathway	3/2112	20/18670	0.398	0.5906	0.4267	BIRC3/DDX58/DDX60	3
BP	GO:0042276	error-prone translesion synthesis	3/2112	20/18670	0.398	0.5906	0.4267	REV3L/RFC3/POLE2	3
BP	GO:0043371	negative regulation of CD4-positive, alpha-beta T cell differentiation	3/2112	20/18670	0.398	0.5906	0.4267	RUNX3/IL4R/TBX21	3
BP	GO:0051016	barbed-end actin filament capping	3/2112	20/18670	0.398	0.5906	0.4267	ADD3/CAPZA1/GSN	3
BP	GO:0051580	regulation of neurotransmitter uptake	3/2112	20/18670	0.398	0.5906	0.4267	PER2/ARL6IP5/ATP1A2	3
BP	GO:0051797	regulation of hair follicle development	3/2112	20/18670	0.398	0.5906	0.4267	FST/FERMT1/SPINK5	3
BP	GO:0060008	Sertoli cell differentiation	3/2112	20/18670	0.398	0.5906	0.4267	SOX9/ICAM1/ATRX	3
BP	GO:0060039	pericardium development	3/2112	20/18670	0.398	0.5906	0.4267	LRP6/SMAD3/NOTCH1	3
BP	GO:0070932	histone H3 deacetylation	3/2112	20/18670	0.398	0.5906	0.4267	SIRT7/HDAC4/PER2	3
BP	GO:0086014	atrial cardiac muscle cell action potential	3/2112	20/18670	0.398	0.5906	0.4267	ANK2/KCNJ5/GJC1	3
BP	GO:0086026	atrial cardiac muscle cell to AV node cell signaling	3/2112	20/18670	0.398	0.5906	0.4267	ANK2/KCNJ5/GJC1	3
BP	GO:0086066	atrial cardiac muscle cell to AV node cell communication	3/2112	20/18670	0.398	0.5906	0.4267	ANK2/KCNJ5/GJC1	3
BP	GO:0098698	postsynaptic specialization assembly	3/2112	20/18670	0.398	0.5906	0.4267	PTPRD/NLGN1/PTPRS	3
BP	GO:1900151	regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	3/2112	20/18670	0.398	0.5906	0.4267	ZFP36L1/TOB1/ZFP36L2	3
BP	GO:1900424	regulation of defense response to bacterium	3/2112	20/18670	0.398	0.5906	0.4267	CXCL6/CYBA/SPINK5	3
BP	GO:0001974	blood vessel remodeling	6/2112	45/18670	0.4007	0.5906	0.4267	CCR2/FOXC1/AXL/BGN/BAK1/TGM2	6
BP	GO:0014014	negative regulation of gliogenesis	6/2112	45/18670	0.4007	0.5906	0.4267	SKI/IDH2/PTN/DAAM2/NOTCH1/RNF10	6
BP	GO:0016574	histone ubiquitination	6/2112	45/18670	0.4007	0.5906	0.4267	SKP1/UBE2B/PAF1/SUZ12/CUL4B/WAC	6
BP	GO:0031018	endocrine pancreas development	6/2112	45/18670	0.4007	0.5906	0.4267	BMP4/SOX9/BAK1/FOXO1/ARNTL/IL6	6
BP	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	6/2112	45/18670	0.4007	0.5906	0.4267	CD74/CDIP1/TP63/HIPK2/TP53/PML	6
BP	GO:0048538	thymus development	6/2112	45/18670	0.4007	0.5906	0.4267	BCL11B/CCNB2/SIX1/SOD1/PBX1/JARID2	6
BP	GO:0090278	negative regulation of peptide hormone secretion	6/2112	45/18670	0.4007	0.5906	0.4267	SFRP1/PPP3CA/KLF7/PTPN11/LEP/HADH	6
BP	GO:0002002	regulation of angiotensin levels in blood	2/2112	12/18670	0.4008	0.5906	0.4267	CPA3/REN	2
BP	GO:0002003	angiotensin maturation	2/2112	12/18670	0.4008	0.5906	0.4267	CPA3/REN	2
BP	GO:0003161	cardiac conduction system development	2/2112	12/18670	0.4008	0.5906	0.4267	BMPR1A/NOTCH1	2
BP	GO:0003207	cardiac chamber formation	2/2112	12/18670	0.4008	0.5906	0.4267	SMARCD3/NOTCH1	2
BP	GO:0006216	cytidine catabolic process	2/2112	12/18670	0.4008	0.5906	0.4267	APOBEC3G/APOBEC3B	2
BP	GO:0006554	lysine catabolic process	2/2112	12/18670	0.4008	0.5906	0.4267	ALDH7A1/AASS	2
BP	GO:0006983	ER overload response	2/2112	12/18670	0.4008	0.5906	0.4267	DDIT3/TP53	2
BP	GO:0009265	2'-deoxyribonucleotide biosynthetic process	2/2112	12/18670	0.4008	0.5906	0.4267	ADK/TYMS	2
BP	GO:0009972	cytidine deamination	2/2112	12/18670	0.4008	0.5906	0.4267	APOBEC3G/APOBEC3B	2
BP	GO:0010623	programmed cell death involved in cell development	2/2112	12/18670	0.4008	0.5906	0.4267	KITLG/IL1B	2
BP	GO:0010649	regulation of cell communication by electrical coupling	2/2112	12/18670	0.4008	0.5906	0.4267	SRI/SLC8A1	2
BP	GO:0010960	magnesium ion homeostasis	2/2112	12/18670	0.4008	0.5906	0.4267	EGFR/CNNM2	2
BP	GO:0014831	gastro-intestinal system smooth muscle contraction	2/2112	12/18670	0.4008	0.5906	0.4267	SULF1/HTR2B	2
BP	GO:0016554	cytidine to uridine editing	2/2112	12/18670	0.4008	0.5906	0.4267	APOBEC3G/APOBEC3B	2
BP	GO:0019374	galactolipid metabolic process	2/2112	12/18670	0.4008	0.5906	0.4267	FA2H/ALDH5A1	2
BP	GO:0019755	one-carbon compound transport	2/2112	12/18670	0.4008	0.5906	0.4267	AQP9/CA2	2
BP	GO:0021819	layer formation in cerebral cortex	2/2112	12/18670	0.4008	0.5906	0.4267	GLI3/MBOAT7	2
BP	GO:0030157	pancreatic juice secretion	2/2112	12/18670	0.4008	0.5906	0.4267	NR1H3/NPR3	2
BP	GO:0030950	establishment or maintenance of actin cytoskeleton polarity	2/2112	12/18670	0.4008	0.5906	0.4267	RHOF/RHOD	2
BP	GO:0033523	histone H2B ubiquitination	2/2112	12/18670	0.4008	0.5906	0.4267	PAF1/WAC	2
BP	GO:0035330	regulation of hippo signaling	2/2112	12/18670	0.4008	0.5906	0.4267	DLG5/MOB3B	2
BP	GO:0035630	bone mineralization involved in bone maturation	2/2112	12/18670	0.4008	0.5906	0.4267	IGF1/LEP	2
BP	GO:0038003	opioid receptor signaling pathway	2/2112	12/18670	0.4008	0.5906	0.4267	SIGMAR1/OGFRL1	2
BP	GO:0038180	nerve growth factor signaling pathway	2/2112	12/18670	0.4008	0.5906	0.4267	CORO1A/MAGI2	2
BP	GO:0042118	endothelial cell activation	2/2112	12/18670	0.4008	0.5906	0.4267	CXCL10/APOLD1	2
BP	GO:0046087	cytidine metabolic process	2/2112	12/18670	0.4008	0.5906	0.4267	APOBEC3G/APOBEC3B	2
BP	GO:0046385	deoxyribose phosphate biosynthetic process	2/2112	12/18670	0.4008	0.5906	0.4267	ADK/TYMS	2
BP	GO:0051095	regulation of helicase activity	2/2112	12/18670	0.4008	0.5906	0.4267	MCM2/TP53	2
BP	GO:0051956	negative regulation of amino acid transport	2/2112	12/18670	0.4008	0.5906	0.4267	ARL6IP5/LEP	2
BP	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation	2/2112	12/18670	0.4008	0.5906	0.4267	PMEPA1/LDLRAD4	2
BP	GO:0060442	branching involved in prostate gland morphogenesis	2/2112	12/18670	0.4008	0.5906	0.4267	SFRP1/BMP4	2
BP	GO:0070586	cell-cell adhesion involved in gastrulation	2/2112	12/18670	0.4008	0.5906	0.4267	ADIPOQ/IL1RN	2
BP	GO:0070601	centromeric sister chromatid cohesion	2/2112	12/18670	0.4008	0.5906	0.4267	BUB1/BUB1B	2
BP	GO:0071712	ER-associated misfolded protein catabolic process	2/2112	12/18670	0.4008	0.5906	0.4267	VCP/SDF2L1	2
BP	GO:0072178	nephric duct morphogenesis	2/2112	12/18670	0.4008	0.5906	0.4267	BMP4/AHI1	2
BP	GO:0072578	neurotransmitter-gated ion channel clustering	2/2112	12/18670	0.4008	0.5906	0.4267	GLRB/NLGN1	2
BP	GO:0072697	protein localization to cell cortex	2/2112	12/18670	0.4008	0.5906	0.4267	EPB41L2/PLK1	2
BP	GO:0090085	regulation of protein deubiquitination	2/2112	12/18670	0.4008	0.5906	0.4267	TRIM21/VCP	2
BP	GO:0090220	chromosome localization to nuclear envelope involved in homologous chromosome segregation	2/2112	12/18670	0.4008	0.5906	0.4267	UBE2B/TERF1	2
BP	GO:0097090	presynaptic membrane organization	2/2112	12/18670	0.4008	0.5906	0.4267	PTPRD/NLGN1	2
BP	GO:0097340	inhibition of cysteine-type endopeptidase activity	2/2112	12/18670	0.4008	0.5906	0.4267	BIRC3/CST7	2
BP	GO:0097341	zymogen inhibition	2/2112	12/18670	0.4008	0.5906	0.4267	BIRC3/CST7	2
BP	GO:0098789	pre-mRNA cleavage required for polyadenylation	2/2112	12/18670	0.4008	0.5906	0.4267	CPSF6/CSTF2	2
BP	GO:0098974	postsynaptic actin cytoskeleton organization	2/2112	12/18670	0.4008	0.5906	0.4267	MYH10/WASF2	2
BP	GO:0099150	regulation of postsynaptic specialization assembly	2/2112	12/18670	0.4008	0.5906	0.4267	PTPRD/PTPRS	2
BP	GO:0099550	trans-synaptic signaling, modulating synaptic transmission	2/2112	12/18670	0.4008	0.5906	0.4267	NTRK2/PLAT	2
BP	GO:0099640	axo-dendritic protein transport	2/2112	12/18670	0.4008	0.5906	0.4267	PURA/HSPB1	2
BP	GO:0150052	regulation of postsynapse assembly	2/2112	12/18670	0.4008	0.5906	0.4267	PTPRD/PTPRS	2
BP	GO:1900044	regulation of protein K63-linked ubiquitination	2/2112	12/18670	0.4008	0.5906	0.4267	NOD2/PTPN22	2
BP	GO:1900402	regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter	2/2112	12/18670	0.4008	0.5906	0.4267	FOXO1/TP53	2
BP	GO:1901387	positive regulation of voltage-gated calcium channel activity	2/2112	12/18670	0.4008	0.5906	0.4267	CACNA2D1/FGF14	2
BP	GO:1902287	semaphorin-plexin signaling pathway involved in axon guidance	2/2112	12/18670	0.4008	0.5906	0.4267	SEMA3A/SEMA3F	2
BP	GO:1902510	regulation of apoptotic DNA fragmentation	2/2112	12/18670	0.4008	0.5906	0.4267	APAF1/IL6	2
BP	GO:1904862	inhibitory synapse assembly	2/2112	12/18670	0.4008	0.5906	0.4267	SEMA4A/SEMA4D	2
BP	GO:1904953	Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation	2/2112	12/18670	0.4008	0.5906	0.4267	LRP6/RYK	2
BP	GO:1905244	regulation of modification of synaptic structure	2/2112	12/18670	0.4008	0.5906	0.4267	ITSN1/CHMP2B	2
BP	GO:1905522	negative regulation of macrophage migration	2/2112	12/18670	0.4008	0.5906	0.4267	SLAMF8/CD200	2
BP	GO:2001053	regulation of mesenchymal cell apoptotic process	2/2112	12/18670	0.4008	0.5906	0.4267	GDF5/SOX9	2
BP	GO:0051053	negative regulation of DNA metabolic process	19/2112	156/18670	0.4024	0.5928	0.4283	GZMA/TTF1/BLM/KMT2A/KCNK2/STAG2/TSPYL2/DONSON/TIMELESS/RGN/TERF1/ADIPOQ/FBXO5/PARP1/ERCC1/THOC1/SMCHD1/TP53/DNAJC2	19
BP	GO:0006835	dicarboxylic acid transport	12/2112	96/18670	0.4027	0.593	0.4285	NTRK2/SLC26A2/SLC1A3/SLC25A22/PER2/ARL6IP5/KMO/ATP1A2/PRAF2/VAMP2/STXBP1/LRRC8D	12
BP	GO:0033108	mitochondrial respiratory chain complex assembly	12/2112	96/18670	0.4027	0.593	0.4285	SCO2/NDUFC1/NDUFS2/NDUFS4/NDUFA13/NDUFAF3/NUBPL/NDUFA9/TFAM/ECSIT/NDUFB6/UQCC1	12
BP	GO:0009880	embryonic pattern specification	8/2112	62/18670	0.4032	0.5935	0.4288	LRP6/ZBTB16/SEMA3A/COBL/MEOX1/SEMA3F/SMAD3/STIL	8
BP	GO:0051898	negative regulation of protein kinase B signaling	8/2112	62/18670	0.4032	0.5935	0.4288	PLEKHA1/HLA-G/BTN2A2/DAG1/MAGI2/PHLPP1/DDIT3/SH2B3	8
BP	GO:0006446	regulation of translational initiation	10/2112	79/18670	0.4035	0.5936	0.4289	CCL5/TPR/EIF3E/EIF5B/DAZL/PPP1CA/EIF4B/DDX1/HSPB1/KHDRBS1	10
BP	GO:0007032	endosome organization	10/2112	79/18670	0.4035	0.5936	0.4289	DNM1/HOOK2/RAB27A/VPS37C/SCARB2/CHMP2B/SNX10/STX6/TMCC1/CHMP1B	10
BP	GO:0007586	digestion	17/2112	139/18670	0.4047	0.5951	0.43	TYMP/SERPINA3/SOX9/PIR/NOD2/CD36/AKR1C1/TAC1/RBP4/LEP/NR1H3/CTRB2/SNX10/NPR3/UGCG/SLC2A5/SOAT2	17
BP	GO:0035304	regulation of protein dephosphorylation	17/2112	139/18670	0.4047	0.5951	0.43	PTPRC/LILRB2/JAK2/DLC1/PHACTR2/MAGI2/PPP1R16B/PTN/NCKAP1L/MFHAS1/RGN/HSP90AB1/PINK1/ENSA/PPP1R11/CAMTA1/CDH5	17
BP	GO:0032412	regulation of ion transmembrane transporter activity	31/2112	260/18670	0.4059	0.5967	0.4311	CCR2/SRI/CACNA2D1/ANK2/FXYD1/DYSF/FXYD6/NETO2/ANXA3/GEM/FHL1/PLCG2/AHCYL1/NLGN1/PLN/ATP1B1/SCN1B/IFNG/RGN/ATP1A2/FGF14/P2RY6/VAMP2/PINK1/TESC/PKD2/GSTO1/KCNAB1/GSTM2/CCL2/GPD1L	31
BP	GO:0031497	chromatin assembly	20/2112	165/18670	0.4067	0.5978	0.4319	NAP1L2/NAP1L3/SOX9/SMARCA1/HJURP/TPR/TSPYL2/ATRX/MCM2/ASF1B/KAT6B/PAF1/HELLS/RSF1/CHAF1B/HMGA1/CENPM/SMCHD1/TP53/HP1BP3	20
BP	GO:0006333	chromatin assembly or disassembly	23/2112	191/18670	0.4079	0.5992	0.433	NAP1L2/NAP1L3/SOX9/SMARCA1/HJURP/TPR/SMARCD3/TSPYL2/SMARCC2/ATRX/MCM2/ASF1B/SMARCD1/KAT6B/PAF1/HELLS/RSF1/CHAF1B/HMGA1/CENPM/SMCHD1/TP53/HP1BP3	23
BP	GO:0019080	viral gene expression	23/2112	191/18670	0.4079	0.5992	0.433	CCL5/NUCKS1/CHD1/RPL31/NUP93/RPL24/TPR/CCNT1/SP1/NUP160/LEF1/TRIM21/GTF2F1/RPS4X/EIF3L/RPL12/POLR2L/RSF1/NUP88/RPL15/NUP50/RPL10A/RPS14	23
BP	GO:0016236	macroautophagy	35/2112	295/18670	0.4086	0.5998	0.4334	UCHL1/GABARAPL1/TBC1D5/TCIRG1/PIP4K2B/RIPK2/GABARAPL2/DCN/NPC1/MTMR14/RAB33B/VPS16/SNX5/VPS37C/FEZ1/VCP/PIK3CA/ATG3/IKBKG/PINK1/CHMP2B/PIP4K2A/SESN1/NOD1/EPM2A/EMC6/KDR/FEZ2/FYCO1/WAC/TP53/BNIP3L/PRKAB1/ATP6V1B2/PIM2	35
BP	GO:0006641	triglyceride metabolic process	13/2112	105/18670	0.409	0.5998	0.4334	GK/SIK1/PCK1/PTPN11/LIPG/RGN/FABP5/CETP/NR1H3/FABP4/SLC27A5/CAT/LIPC	13
BP	GO:0015748	organophosphate ester transport	13/2112	105/18670	0.409	0.5998	0.4334	ABCG1/ATP8B2/ATP8A1/ATP9A/SLC25A36/SLC37A1/SLC25A4/SLC25A23/CETP/PITPNC1/SCARB2/STARD7/SLC25A5	13
BP	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion	5/2112	37/18670	0.4094	0.5998	0.4334	RFC3/PARP1/CUL4B/ERCC1/GTF2H5	5
BP	GO:0007099	centriole replication	5/2112	37/18670	0.4094	0.5998	0.4334	CETN2/CEP135/PLK2/CEP63/STIL	5
BP	GO:0030201	heparan sulfate proteoglycan metabolic process	5/2112	37/18670	0.4094	0.5998	0.4334	SULF1/EXTL2/TCF7L2/UGDH/EXT2	5
BP	GO:0032941	secretion by tissue	5/2112	37/18670	0.4094	0.5998	0.4334	ADA/TAC1/NR1H3/CYBA/NPR3	5
BP	GO:0043243	positive regulation of protein complex disassembly	5/2112	37/18670	0.4094	0.5998	0.4334	PLEK/DSTN/CFL1/WDR1/FYCO1	5
BP	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	5/2112	37/18670	0.4094	0.5998	0.4334	GATA2/FGF2/PLK2/AKT3/KDR	5
BP	GO:1904358	positive regulation of telomere maintenance via telomere lengthening	5/2112	37/18670	0.4094	0.5998	0.4334	PRKCQ/NEK7/NEK2/AURKB/PARN	5
BP	GO:2000142	regulation of DNA-templated transcription, initiation	5/2112	37/18670	0.4094	0.5998	0.4334	TAF7/HEY2/FOSL1/TP53/THRA	5
BP	GO:0022404	molting cycle process	11/2112	88/18670	0.4108	0.6013	0.4344	IGFBP5/SOX9/INHBA/FGF7/EGFR/TP63/NOTCH1/FZD6/FST/FERMT1/SPINK5	11
BP	GO:0022405	hair cycle process	11/2112	88/18670	0.4108	0.6013	0.4344	IGFBP5/SOX9/INHBA/FGF7/EGFR/TP63/NOTCH1/FZD6/FST/FERMT1/SPINK5	11
BP	GO:0098773	skin epidermis development	11/2112	88/18670	0.4108	0.6013	0.4344	IGFBP5/SOX9/INHBA/FGF7/EGFR/TP63/NOTCH1/FZD6/FST/FERMT1/SPINK5	11
BP	GO:1903321	negative regulation of protein modification by small protein conjugation or removal	11/2112	88/18670	0.4108	0.6013	0.4344	TNFAIP3/DYSF/MAD2L1/BAG2/PER2/TRIM21/FBXO5/IVNS1ABP/BAG5/CAMLG/ISG15	11
BP	GO:0006584	catecholamine metabolic process	7/2112	54/18670	0.412	0.6027	0.4355	GCH1/ITGB2/SNCAIP/AKR1B1/MAOA/AOC2/MAOB	7
BP	GO:0009066	aspartate family amino acid metabolic process	7/2112	54/18670	0.412	0.6027	0.4355	BHMT2/ALDH7A1/ASPA/AHCYL1/MAT1A/AHCYL2/AASS	7
BP	GO:0009712	catechol-containing compound metabolic process	7/2112	54/18670	0.412	0.6027	0.4355	GCH1/ITGB2/SNCAIP/AKR1B1/MAOA/AOC2/MAOB	7
BP	GO:0006690	icosanoid metabolic process	14/2112	114/18670	0.4146	0.6063	0.4381	LTC4S/AKR1C3/TLR2/CD74/HPGDS/PLA2G4C/GPX4/SYK/FABP5/MAPKAPK2/PTGS1/IL1B/EPHX2/ALOX5	14
BP	GO:0006942	regulation of striated muscle contraction	12/2112	97/18670	0.4171	0.6098	0.4406	SRI/ANK2/HDAC4/FGF13/PLN/KCNJ2/ATP1B1/DSC2/ATP1A2/SLC8A1/GSTO1/GSTM2	12
BP	GO:0022412	cellular process involved in reproduction in multicellular organism	42/2112	357/18670	0.4175	0.6101	0.4408	SFRP1/BMP4/IGF1/ASPM/SERPINA5/ZBTB16/FOXC1/INHBA/JAM3/NPR2/PLK1/UBE2B/NCAPH/DZIP1/ETV5/CDC25B/SRPK1/TTLL1/PTN/DAZL/TOP2A/FZD4/MYBL1/ETV6/SMARCA2/CD9/CCNB1/ACVR1/FBXO5/FOSL1/SPAG16/REC8/TTK/FOXO3/UBE2J1/DDX6/ANG/ERCC1/TRIP13/AURKA/YBX2/PTX3	42
BP	GO:0000132	establishment of mitotic spindle orientation	4/2112	29/18670	0.419	0.6101	0.4408	NDC80/MAD2L1/PLK1/MCPH1	4
BP	GO:0006294	nucleotide-excision repair, preincision complex assembly	4/2112	29/18670	0.419	0.6101	0.4408	CETN2/PARP1/CUL4B/GTF2H5	4
BP	GO:0010390	histone monoubiquitination	4/2112	29/18670	0.419	0.6101	0.4408	SKP1/PAF1/CUL4B/WAC	4
BP	GO:0010669	epithelial structure maintenance	4/2112	29/18670	0.419	0.6101	0.4408	SERPINA3/SOX9/NOD2/RBP4	4
BP	GO:0016577	histone demethylation	4/2112	29/18670	0.419	0.6101	0.4408	UBE2B/JARID2/KDM7A/KDM2A	4
BP	GO:0021799	cerebral cortex radially oriented cell migration	4/2112	29/18670	0.419	0.6101	0.4408	GLI3/DIXDC1/POU3F3/MBOAT7	4
BP	GO:0031114	regulation of microtubule depolymerization	4/2112	29/18670	0.419	0.6101	0.4408	CKAP2/FGF13/CAMSAP2/MAP1B	4
BP	GO:0031116	positive regulation of microtubule polymerization	4/2112	29/18670	0.419	0.6101	0.4408	MECP2/TERF1/PAK1/MAP1B	4
BP	GO:0042219	cellular modified amino acid catabolic process	4/2112	29/18670	0.419	0.6101	0.4408	PCYOX1/DIO2/ACADL/DIO3	4
BP	GO:0044550	secondary metabolite biosynthetic process	4/2112	29/18670	0.419	0.6101	0.4408	CBS/SP1/TRPC1/BDH2	4
BP	GO:0048261	negative regulation of receptor-mediated endocytosis	4/2112	29/18670	0.419	0.6101	0.4408	LRPAP1/ATXN2/MTMR2/SH3GL3	4
BP	GO:0048730	epidermis morphogenesis	4/2112	29/18670	0.419	0.6101	0.4408	IGFBP5/FGF7/TP63/NOTCH1	4
BP	GO:0050974	detection of mechanical stimulus involved in sensory perception	4/2112	29/18670	0.419	0.6101	0.4408	CXCR4/HTR2A/PIEZO2/BACE1	4
BP	GO:0090162	establishment of epithelial cell polarity	4/2112	29/18670	0.419	0.6101	0.4408	CYTH1/PARD3/FERMT1/MPP5	4
BP	GO:0120033	negative regulation of plasma membrane bounded cell projection assembly	4/2112	29/18670	0.419	0.6101	0.4408	PFN2/MAP4/CCL21/KANK1	4
BP	GO:2000036	regulation of stem cell population maintenance	4/2112	29/18670	0.419	0.6101	0.4408	YAP1/PTN/TP63/ZNF322	4
BP	GO:0140029	exocytic process	10/2112	80/18670	0.4194	0.6106	0.4411	RAB8A/PLEK/NLGN1/STXBP2/STX4/SYK/STXBP1/BTK/LYN/VTI1B	10
BP	GO:0006520	cellular amino acid metabolic process	43/2112	366/18670	0.4197	0.6108	0.4413	PSMB9/BHMT2/PSMB8/FAH/CDO1/IDO1/NQO1/ALDH7A1/PSMB10/PCYOX1/SERINC3/KYNU/ALDH6A1/CBS/PCBD1/BPHL/PSME1/OAT/DDAH2/SLC1A3/MCCC1/ASPA/CRTAP/AHCYL1/ACAT1/NOX4/NAALAD2/HPD/MAT1A/GFPT1/P4HTM/PSPH/KMO/MECP2/FN3K/AHCYL2/BCKDHB/FOLH1/AASS/WARS2/GFPT2/ALDH5A1/TXN2	43
BP	GO:0006893	Golgi to plasma membrane transport	8/2112	63/18670	0.4212	0.6126	0.4426	CSK/PREPL/TRIM23/BBS1/VAMP2/ARL3/GOLGA7/SPTBN1	8
BP	GO:0032371	regulation of sterol transport	8/2112	63/18670	0.4212	0.6126	0.4426	ABCG1/NFKBIA/NFKB1/LIPG/LEP/ADIPOQ/CETP/NR1H3	8
BP	GO:0032374	regulation of cholesterol transport	8/2112	63/18670	0.4212	0.6126	0.4426	ABCG1/NFKBIA/NFKB1/LIPG/LEP/ADIPOQ/CETP/NR1H3	8
BP	GO:0032527	protein exit from endoplasmic reticulum	6/2112	46/18670	0.4217	0.6131	0.443	EDEM1/VCP/UBE2J1/CD81/EDEM2/UBE2G2	6
BP	GO:0035196	production of miRNAs involved in gene silencing by miRNA	6/2112	46/18670	0.4217	0.6131	0.443	BMP4/PPP3CA/EGFR/SMAD3/ADAR/TP53	6
BP	GO:0071824	protein-DNA complex subunit organization	34/2112	288/18670	0.4226	0.6142	0.4438	NAP1L2/NAP1L3/SOX9/CETN2/CDC45/SMARCA1/TAF7/HJURP/SMARCD3/TSPYL2/MCM5/SMARCC2/ATRX/MCM2/HEY2/ASF1B/TERF1/SMARCD1/PARP1/KAT6B/PAF1/CENPF/HELLS/RSF1/RB1/CHAF1B/MCM4/CUL4B/HMGA1/CENPM/TP53/HP1BP3/THRA/GTF2H5	34
BP	GO:0016482	cytosolic transport	19/2112	158/18670	0.425	0.6175	0.4462	ARL1/CORO1A/PREPL/EMP2/RHOBTB3/TBC1D5/GAK/HOOK2/STX16/SNX5/KIF16B/SYBU/AP1AR/STX6/MTMR2/VTI1B/RAB14/KIF1B/ACTR2	19
BP	GO:0030449	regulation of complement activation	14/2112	115/18670	0.4278	0.6197	0.4477	CLU/CFP/PROS1/CR1/CD19/IGLC1/IGLV1-44/C7/IGHG1/CFB/CD81/IL1B/CR2/C6	14
BP	GO:0002377	immunoglobulin production	23/2112	193/18670	0.4283	0.6197	0.4477	XCL1/PTPRC/IL27RA/IL7R/TRDV3/BATF/SASH3/TCIRG1/IL4R/CD40/TFRC/HLA-E/TBX21/IL13RA2/CD40LG/RBP4/IGLV1-44/STX4/BTK/TNFRSF4/IL6/ERCC1/THOC1	23
BP	GO:0001956	positive regulation of neurotransmitter secretion	3/2112	21/18670	0.4297	0.6197	0.4477	NLGN1/KMO/STXBP1	3
BP	GO:0002029	desensitization of G protein-coupled receptor signaling pathway	3/2112	21/18670	0.4297	0.6197	0.4477	HTR2B/DNM1/APLNR	3
BP	GO:0003283	atrial septum development	3/2112	21/18670	0.4297	0.6197	0.4477	ANK2/HEY2/ACVR1	3
BP	GO:0006067	ethanol metabolic process	3/2112	21/18670	0.4297	0.6197	0.4477	ADH1C/ADH1B/ADH5	3
BP	GO:0010310	regulation of hydrogen peroxide metabolic process	3/2112	21/18670	0.4297	0.6197	0.4477	RAC2/PINK1/HP	3
BP	GO:0010893	positive regulation of steroid biosynthetic process	3/2112	21/18670	0.4297	0.6197	0.4477	ABCG1/IFNG/IL1B	3
BP	GO:0016553	base conversion or substitution editing	3/2112	21/18670	0.4297	0.6197	0.4477	APOBEC3G/APOBEC3B/ADAR	3
BP	GO:0017000	antibiotic biosynthetic process	3/2112	21/18670	0.4297	0.6197	0.4477	SOD1/MAOB/CYBA	3
BP	GO:0019682	glyceraldehyde-3-phosphate metabolic process	3/2112	21/18670	0.4297	0.6197	0.4477	RPIA/PGD/TALDO1	3
BP	GO:0022401	negative adaptation of signaling pathway	3/2112	21/18670	0.4297	0.6197	0.4477	HTR2B/DNM1/APLNR	3
BP	GO:0033962	cytoplasmic mRNA processing body assembly	3/2112	21/18670	0.4297	0.6197	0.4477	DDX6/LSM3/ATXN2	3
BP	GO:0035357	peroxisome proliferator activated receptor signaling pathway	3/2112	21/18670	0.4297	0.6197	0.4477	LMO3/LEP/FABP5	3
BP	GO:0036507	protein demannosylation	3/2112	21/18670	0.4297	0.6197	0.4477	EDEM1/MAN1C1/EDEM2	3
BP	GO:0036508	protein alpha-1,2-demannosylation	3/2112	21/18670	0.4297	0.6197	0.4477	EDEM1/MAN1C1/EDEM2	3
BP	GO:0039531	regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway	3/2112	21/18670	0.4297	0.6197	0.4477	BIRC3/TSPAN6/DDX60	3
BP	GO:0039702	viral budding via host ESCRT complex	3/2112	21/18670	0.4297	0.6197	0.4477	VPS37C/CHMP2B/CHMP1B	3
BP	GO:0042403	thyroid hormone metabolic process	3/2112	21/18670	0.4297	0.6197	0.4477	DIO2/CPQ/DIO3	3
BP	GO:0042749	regulation of circadian sleep/wake cycle	3/2112	21/18670	0.4297	0.6197	0.4477	ADA/NLGN1/PER3	3
BP	GO:0043984	histone H4-K16 acetylation	3/2112	21/18670	0.4297	0.6197	0.4477	AUTS2/KMT2A/MSL3	3
BP	GO:0046132	pyrimidine ribonucleoside biosynthetic process	3/2112	21/18670	0.4297	0.6197	0.4477	UPP1/NME7/NME4	3
BP	GO:0048485	sympathetic nervous system development	3/2112	21/18670	0.4297	0.6197	0.4477	SEMA3A/TP63/SEMA3F	3
BP	GO:0051383	kinetochore organization	3/2112	21/18670	0.4297	0.6197	0.4477	NDC80/CENPF/SMC4	3
BP	GO:0060713	labyrinthine layer morphogenesis	3/2112	21/18670	0.4297	0.6197	0.4477	SPINT2/LEF1/ZFP36L1	3
BP	GO:0060972	left/right pattern formation	3/2112	21/18670	0.4297	0.6197	0.4477	NOTCH1/MEGF8/AHI1	3
BP	GO:0070584	mitochondrion morphogenesis	3/2112	21/18670	0.4297	0.6197	0.4477	PID1/FEZ1/NUBPL	3
BP	GO:0090280	positive regulation of calcium ion import	3/2112	21/18670	0.4297	0.6197	0.4477	TRPV2/CCL2/CASK	3
BP	GO:0098743	cell aggregation	3/2112	21/18670	0.4297	0.6197	0.4477	MGP/SOX9/THRA	3
BP	GO:1902307	positive regulation of sodium ion transmembrane transport	3/2112	21/18670	0.4297	0.6197	0.4477	FXYD1/ATP1B1/TESC	3
BP	GO:2000737	negative regulation of stem cell differentiation	3/2112	21/18670	0.4297	0.6197	0.4477	YAP1/NOTCH1/ZFP36L2	3
BP	GO:2000810	regulation of bicellular tight junction assembly	3/2112	21/18670	0.4297	0.6197	0.4477	PRKCH/MYO1C/NPHP4	3
BP	GO:2001014	regulation of skeletal muscle cell differentiation	3/2112	21/18670	0.4297	0.6197	0.4477	SIX1/EPHB1/ARNTL	3
BP	GO:0006576	cellular biogenic amine metabolic process	7/2112	55/18670	0.4313	0.6213	0.4489	IDO1/ALDH7A1/KYNU/MAOA/KMO/MECP2/NAAA	7
BP	GO:0016233	telomere capping	7/2112	55/18670	0.4313	0.6213	0.4489	PRKCQ/NEK7/NEK2/TERF1/AURKB/ERCC1/USP7	7
BP	GO:0070830	bicellular tight junction assembly	7/2112	55/18670	0.4313	0.6213	0.4489	PRKCH/PARD3/ECT2/PECAM1/MYO1C/MPP5/NPHP4	7
BP	GO:0098900	regulation of action potential	7/2112	55/18670	0.4313	0.6213	0.4489	CACNA2D1/ANK2/CD36/TAC1/FGF13/KCNJ2/DSC2	7
BP	GO:0042472	inner ear morphogenesis	12/2112	98/18670	0.4315	0.6214	0.449	ZIC1/SOX9/SIX1/GATA2/SOBP/SOD1/TFAP2A/FGF9/FZD6/DVL1/MYO3A/FZD2	12
BP	GO:0007043	cell-cell junction assembly	15/2112	124/18670	0.4325	0.6215	0.449	PRKCH/DLG5/CDH19/PARD3/ANK2/CDH2/CD9/ECT2/PECAM1/MYO1C/MPP5/GJC1/WDR1/NPHP4/CDH5	15
BP	GO:0031123	RNA 3'-end processing	18/2112	150/18670	0.4326	0.6215	0.449	CPEB1/CPSF6/BARD1/CCNT1/AHCYL1/CSTF2/ZFP36L1/ERI3/CCNB1/THOC2/PAF1/DDX39A/RPRD1A/CLP1/THOC1/EXOSC7/THOC6/PARN	18
BP	GO:0003298	physiological muscle hypertrophy	5/2112	38/18670	0.4327	0.6215	0.449	IGF1/SORBS2/PDLIM5/PAK1/AKAP13	5
BP	GO:0003301	physiological cardiac muscle hypertrophy	5/2112	38/18670	0.4327	0.6215	0.449	IGF1/SORBS2/PDLIM5/PAK1/AKAP13	5
BP	GO:0019068	virion assembly	5/2112	38/18670	0.4327	0.6215	0.449	PC/VPS37C/CHMP2B/DDX6/CHMP1B	5
BP	GO:0046326	positive regulation of glucose import	5/2112	38/18670	0.4327	0.6215	0.449	PIK3R1/IGF1/PTPN11/ADIPOQ/SORBS1	5
BP	GO:0046329	negative regulation of JNK cascade	5/2112	38/18670	0.4327	0.6215	0.449	SFRP1/ZMYND11/DACT1/PINK1/PTPN22	5
BP	GO:0046676	negative regulation of insulin secretion	5/2112	38/18670	0.4327	0.6215	0.449	SFRP1/PPP3CA/KLF7/PTPN11/HADH	5
BP	GO:0048246	macrophage chemotaxis	5/2112	38/18670	0.4327	0.6215	0.449	CCL5/SLAMF8/EDNRB/MTUS1/CCL2	5
BP	GO:0061049	cell growth involved in cardiac muscle cell development	5/2112	38/18670	0.4327	0.6215	0.449	IGF1/SORBS2/PDLIM5/PAK1/AKAP13	5
BP	GO:0097064	ncRNA export from nucleus	5/2112	38/18670	0.4327	0.6215	0.449	NUP93/TPR/NUP160/NUP88/NUP50	5
BP	GO:0097352	autophagosome maturation	5/2112	38/18670	0.4327	0.6215	0.449	GABARAPL1/GABARAPL2/VPS16/VCP/FYCO1	5
BP	GO:0021766	hippocampus development	10/2112	81/18670	0.4352	0.6238	0.4507	GLI3/ANXA3/FGF13/EZH2/PTPRS/LEF1/FEZ1/EMX2/EZH1/FEZF2	10
BP	GO:0048708	astrocyte differentiation	10/2112	81/18670	0.4352	0.6238	0.4507	PLP1/SOX9/EGFR/PTPN11/NOTCH1/IL6ST/IFNG/IL6/FPR2/IL1B	10
BP	GO:0060761	negative regulation of response to cytokine stimulus	10/2112	81/18670	0.4352	0.6238	0.4507	CCL5/PTPRC/PTPN2/ADAR/ADIPOQ/IL6/NR1H3/IL1RN/SH2B3/MMP12	10
BP	GO:1903533	regulation of protein targeting	10/2112	81/18670	0.4352	0.6238	0.4507	RAC2/ITGB1BP1/ITGB2/ERBB2/GDI1/PAK1/MYO1C/PINK1/HSPA1L/BNIP3L	10
BP	GO:0098781	ncRNA transcription	13/2112	107/18670	0.4365	0.6238	0.4507	SIRT7/RPAP2/CCNT1/SP1/GTF2F1/NPM3/POLR2L/GTF2A1/RPRD1A/ANG/TP53/SPIN1/SNAPC1	13
BP	GO:0051168	nuclear export	23/2112	194/18670	0.4386	0.6238	0.4507	PTPN14/MALT1/NUP93/XPO6/IFI27/CPSF6/TPR/BARD1/AHCYL1/TCF7L2/NUP160/PTPN11/THOC2/AKAP13/DDX39A/NUP88/THOC1/NUP50/TP53/KHDRBS1/THOC6/IL1B/XPO4	23
BP	GO:0046503	glycerolipid catabolic process	8/2112	64/18670	0.439	0.6238	0.4507	PNPLA6/PLA2G4C/LIPG/PRDX6/FABP5/FABP4/ABHD6/LIPC	8
BP	GO:0048278	vesicle docking	8/2112	64/18670	0.439	0.6238	0.4507	RAB8A/PLEK/STX16/STXBP2/STX4/STXBP1/STX6/VTI1B	8
BP	GO:1903672	positive regulation of sprouting angiogenesis	8/2112	64/18670	0.439	0.6238	0.4507	GATA2/FGF2/PPP1R16B/PLK2/AGTR1/APLNR/AKT3/KDR	8
BP	GO:0009953	dorsal/ventral pattern formation	11/2112	90/18670	0.4409	0.6238	0.4507	SFRP1/BMP4/GLI3/BMPR1A/TCTN1/NBL1/ACVR1/TULP3/DDIT3/HOXA11/RFX4	11
BP	GO:1903035	negative regulation of response to wounding	11/2112	90/18670	0.4409	0.6238	0.4507	PROS1/FGF2/PLAT/PTPRS/SMAD3/CD9/PRKG1/TFPI/SH2B3/GP1BA/CASK	11
BP	GO:2000257	regulation of protein activation cascade	14/2112	116/18670	0.4411	0.6238	0.4507	CLU/CFP/PROS1/CR1/CD19/IGLC1/IGLV1-44/C7/IGHG1/CFB/CD81/IL1B/CR2/C6	14
BP	GO:0000722	telomere maintenance via recombination	2/2112	13/18670	0.4418	0.6238	0.4507	SMC6/ERCC1	2
BP	GO:0001765	membrane raft assembly	2/2112	13/18670	0.4418	0.6238	0.4507	RFTN1/EMP2	2
BP	GO:0001833	inner cell mass cell proliferation	2/2112	13/18670	0.4418	0.6238	0.4507	ZPR1/GINS1	2
BP	GO:0001867	complement activation, lectin pathway	2/2112	13/18670	0.4418	0.6238	0.4507	SCARA3/FCN1	2
BP	GO:0001973	adenosine receptor signaling pathway	2/2112	13/18670	0.4418	0.6238	0.4507	ADA/ADORA3	2
BP	GO:0003157	endocardium development	2/2112	13/18670	0.4418	0.6238	0.4507	NOTCH1/ACVR1	2
BP	GO:0006012	galactose metabolic process	2/2112	13/18670	0.4418	0.6238	0.4507	GALT/SLC35A2	2
BP	GO:0006553	lysine metabolic process	2/2112	13/18670	0.4418	0.6238	0.4507	ALDH7A1/AASS	2
BP	GO:0006707	cholesterol catabolic process	2/2112	13/18670	0.4418	0.6238	0.4507	SCARF1/CYP46A1	2
BP	GO:0006995	cellular response to nitrogen starvation	2/2112	13/18670	0.4418	0.6238	0.4507	GABARAPL1/GABARAPL2	2
BP	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity	2/2112	13/18670	0.4418	0.6238	0.4507	ANGPT1/EFNA5	2
BP	GO:0007494	midgut development	2/2112	13/18670	0.4418	0.6238	0.4507	EGFR/EDNRB	2
BP	GO:0009143	nucleoside triphosphate catabolic process	2/2112	13/18670	0.4418	0.6238	0.4507	ENPP1/ADA	2
BP	GO:0009313	oligosaccharide catabolic process	2/2112	13/18670	0.4418	0.6238	0.4507	MAN2B1/MANBA	2
BP	GO:0009635	response to herbicide	2/2112	13/18670	0.4418	0.6238	0.4507	MAPK13/ALAD	2
BP	GO:0010454	negative regulation of cell fate commitment	2/2112	13/18670	0.4418	0.6238	0.4507	TBX21/FZD7	2
BP	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway	2/2112	13/18670	0.4418	0.6238	0.4507	PTPN2/ADIPOQ	2
BP	GO:0010838	positive regulation of keratinocyte proliferation	2/2112	13/18670	0.4418	0.6238	0.4507	FGF7/TP63	2
BP	GO:0010872	regulation of cholesterol esterification	2/2112	13/18670	0.4418	0.6238	0.4507	ABCG1/AGTR1	2
BP	GO:0016127	sterol catabolic process	2/2112	13/18670	0.4418	0.6238	0.4507	SCARF1/CYP46A1	2
BP	GO:0016322	neuron remodeling	2/2112	13/18670	0.4418	0.6238	0.4507	SCARF1/BCL11A	2
BP	GO:0019511	peptidyl-proline hydroxylation	2/2112	13/18670	0.4418	0.6238	0.4507	CRTAP/P4HTM	2
BP	GO:0021794	thalamus development	2/2112	13/18670	0.4418	0.6238	0.4507	LRP6/PTN	2
BP	GO:0021978	telencephalon regionalization	2/2112	13/18670	0.4418	0.6238	0.4507	BMP4/EMX2	2
BP	GO:0031650	regulation of heat generation	2/2112	13/18670	0.4418	0.6238	0.4507	EDNRB/IL1B	2
BP	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway	2/2112	13/18670	0.4418	0.6238	0.4507	KANK2/TP63	2
BP	GO:0034397	telomere localization	2/2112	13/18670	0.4418	0.6238	0.4507	UBE2B/TERF1	2
BP	GO:0034982	mitochondrial protein processing	2/2112	13/18670	0.4418	0.6238	0.4507	YME1L1/AFG3L2	2
BP	GO:0035641	locomotory exploration behavior	2/2112	13/18670	0.4418	0.6238	0.4507	PENK/C12orf10	2
BP	GO:0036109	alpha-linolenic acid metabolic process	2/2112	13/18670	0.4418	0.6238	0.4507	ELOVL2/ELOVL5	2
BP	GO:0038065	collagen-activated signaling pathway	2/2112	13/18670	0.4418	0.6238	0.4507	DDR2/SYK	2
BP	GO:0042908	xenobiotic transport	2/2112	13/18670	0.4418	0.6238	0.4507	SLC47A1/LRRC8D	2
BP	GO:0043116	negative regulation of vascular permeability	2/2112	13/18670	0.4418	0.6238	0.4507	ANGPT1/AKAP12	2
BP	GO:0043562	cellular response to nitrogen levels	2/2112	13/18670	0.4418	0.6238	0.4507	GABARAPL1/GABARAPL2	2
BP	GO:0043970	histone H3-K9 acetylation	2/2112	13/18670	0.4418	0.6238	0.4507	NAP1L2/KMT2A	2
BP	GO:0045078	positive regulation of interferon-gamma biosynthetic process	2/2112	13/18670	0.4418	0.6238	0.4507	TLR8/CLEC7A	2
BP	GO:0045820	negative regulation of glycolytic process	2/2112	13/18670	0.4418	0.6238	0.4507	CBFA2T3/HDAC4	2
BP	GO:0047484	regulation of response to osmotic stress	2/2112	13/18670	0.4418	0.6238	0.4507	MICU1/SLC25A23	2
BP	GO:0048711	positive regulation of astrocyte differentiation	2/2112	13/18670	0.4418	0.6238	0.4507	NOTCH1/IL6ST	2
BP	GO:0048715	negative regulation of oligodendrocyte differentiation	2/2112	13/18670	0.4418	0.6238	0.4507	DAAM2/NOTCH1	2
BP	GO:0048875	chemical homeostasis within a tissue	2/2112	13/18670	0.4418	0.6238	0.4507	RCN3/CTSH	2
BP	GO:0050722	regulation of interleukin-1 beta biosynthetic process	2/2112	13/18670	0.4418	0.6238	0.4507	JAK2/IFNG	2
BP	GO:0051315	attachment of mitotic spindle microtubules to kinetochore	2/2112	13/18670	0.4418	0.6238	0.4507	NDC80/KIF2C	2
BP	GO:0060123	regulation of growth hormone secretion	2/2112	13/18670	0.4418	0.6238	0.4507	ITSN1/PTPN11	2
BP	GO:0060340	positive regulation of type I interferon-mediated signaling pathway	2/2112	13/18670	0.4418	0.6238	0.4507	IRF7/MMP12	2
BP	GO:0070103	regulation of interleukin-6-mediated signaling pathway	2/2112	13/18670	0.4418	0.6238	0.4507	PTPN2/GFI1	2
BP	GO:0070914	UV-damage excision repair	2/2112	13/18670	0.4418	0.6238	0.4507	CUL4B/ERCC1	2
BP	GO:0070986	left/right axis specification	2/2112	13/18670	0.4418	0.6238	0.4507	NOTCH1/AHI1	2
BP	GO:0071285	cellular response to lithium ion	2/2112	13/18670	0.4418	0.6238	0.4507	FABP4/CEBPA	2
BP	GO:0090239	regulation of histone H4 acetylation	2/2112	13/18670	0.4418	0.6238	0.4507	AUTS2/SPI1	2
BP	GO:0090308	regulation of methylation-dependent chromatin silencing	2/2112	13/18670	0.4418	0.6238	0.4507	DNMT1/MPHOSPH8	2
BP	GO:0090677	reversible differentiation	2/2112	13/18670	0.4418	0.6238	0.4507	DNMT1/FGF9	2
BP	GO:0098787	mRNA cleavage involved in mRNA processing	2/2112	13/18670	0.4418	0.6238	0.4507	CPSF6/CSTF2	2
BP	GO:1900225	regulation of NLRP3 inflammasome complex assembly	2/2112	13/18670	0.4418	0.6238	0.4507	CD36/TLR6	2
BP	GO:1900272	negative regulation of long-term synaptic potentiation	2/2112	13/18670	0.4418	0.6238	0.4507	CX3CR1/PTN	2
BP	GO:1901550	regulation of endothelial cell development	2/2112	13/18670	0.4418	0.6238	0.4507	IL1B/CDH5	2
BP	GO:1902285	semaphorin-plexin signaling pathway involved in neuron projection guidance	2/2112	13/18670	0.4418	0.6238	0.4507	SEMA3A/SEMA3F	2
BP	GO:1902855	regulation of non-motile cilium assembly	2/2112	13/18670	0.4418	0.6238	0.4507	MAP4/CEP135	2
BP	GO:1903140	regulation of establishment of endothelial barrier	2/2112	13/18670	0.4418	0.6238	0.4507	IL1B/CDH5	2
BP	GO:1904293	negative regulation of ERAD pathway	2/2112	13/18670	0.4418	0.6238	0.4507	UBE2J1/UBE2G2	2
BP	GO:2000052	positive regulation of non-canonical Wnt signaling pathway	2/2112	13/18670	0.4418	0.6238	0.4507	SFRP1/PLEKHA4	2
BP	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining	2/2112	13/18670	0.4418	0.6238	0.4507	SETMAR/SMCHD1	2
BP	GO:0021695	cerebellar cortex development	6/2112	47/18670	0.4427	0.6244	0.4511	MYH10/ZNF365/EZH2/PTPN11/CLP1/B4GALT2	6
BP	GO:0030574	collagen catabolic process	6/2112	47/18670	0.4427	0.6244	0.4511	MMP1/CTSL/MRC2/CTSB/COL15A1/MMP12	6
BP	GO:0051181	cofactor transport	6/2112	47/18670	0.4427	0.6244	0.4511	FLVCR2/SLC22A17/CD320/SLC23A2/LMBRD1/SLC5A6	6
BP	GO:0098868	bone growth	6/2112	47/18670	0.4427	0.6244	0.4511	SCARA3/DDR2/COCH/COMP/COL14A1/LEP	6
BP	GO:1901068	guanosine-containing compound metabolic process	6/2112	47/18670	0.4427	0.6244	0.4511	AMPD3/NME7/MOCS2/MBIP/NME4/CASK	6
BP	GO:0000038	very long-chain fatty acid metabolic process	4/2112	30/18670	0.4454	0.6265	0.4526	ELOVL4/SLC27A5/ELOVL2/ELOVL5	4
BP	GO:0003209	cardiac atrium morphogenesis	4/2112	30/18670	0.4454	0.6265	0.4526	SHOX2/NOTCH1/HEY2/ACVR1	4
BP	GO:0003413	chondrocyte differentiation involved in endochondral bone morphogenesis	4/2112	30/18670	0.4454	0.6265	0.4526	SCARA3/SOX9/COCH/COL14A1	4
BP	GO:0007274	neuromuscular synaptic transmission	4/2112	30/18670	0.4454	0.6265	0.4526	ETV5/CHRNA5/STXBP1/KIF1B	4
BP	GO:0035066	positive regulation of histone acetylation	4/2112	30/18670	0.4454	0.6265	0.4526	NAP1L2/AUTS2/RPS6KA4/IL1B	4
BP	GO:0045940	positive regulation of steroid metabolic process	4/2112	30/18670	0.4454	0.6265	0.4526	ABCG1/AGTR1/IFNG/IL1B	4
BP	GO:0046320	regulation of fatty acid oxidation	4/2112	30/18670	0.4454	0.6265	0.4526	ACADVL/ACACB/PDK4/ACADL	4
BP	GO:0048265	response to pain	4/2112	30/18670	0.4454	0.6265	0.4526	GCH1/THBS4/TAC1/EDNRB	4
BP	GO:0048384	retinoic acid receptor signaling pathway	4/2112	30/18670	0.4454	0.6265	0.4526	AKR1C3/DHRS3/EZH2/PML	4
BP	GO:0050690	regulation of defense response to virus by virus	4/2112	30/18670	0.4454	0.6265	0.4526	LCK/CD247/DOCK2/HCK	4
BP	GO:1904292	regulation of ERAD pathway	4/2112	30/18670	0.4454	0.6265	0.4526	EDEM1/UBE2J1/EDEM2/UBE2G2	4
BP	GO:0003208	cardiac ventricle morphogenesis	9/2112	73/18670	0.4455	0.6265	0.4526	FOXC1/ZFPM2/BMPR1A/TGFBR3/SMARCD3/CPE/NOTCH1/HEY2/HEY1	9
BP	GO:1903524	positive regulation of blood circulation	9/2112	73/18670	0.4455	0.6265	0.4526	GCH1/ICAM1/EGFR/ADA/HTR2A/HRH1/OR51E2/HEY2/CD38	9
BP	GO:0043648	dicarboxylic acid metabolic process	12/2112	99/18670	0.4458	0.6268	0.4529	KYNU/OAT/MTHFD2/SLC1A3/IDH2/ASPA/PCK1/SUCLA2/KMO/MDH1/SDHA/ALDH5A1	12
BP	GO:0060113	inner ear receptor cell differentiation	7/2112	56/18670	0.4505	0.6329	0.4573	BMP4/SOD1/NOTCH1/HEY2/FAT4/FZD2/MYCL	7
BP	GO:0072528	pyrimidine-containing compound biosynthetic process	7/2112	56/18670	0.4505	0.6329	0.4573	TYMP/UPP1/NME7/TYMS/NME4/TK2/TK1	7
BP	GO:0120192	tight junction assembly	7/2112	56/18670	0.4505	0.6329	0.4573	PRKCH/PARD3/ECT2/PECAM1/MYO1C/MPP5/NPHP4	7
BP	GO:0060538	skeletal muscle organ development	20/2112	169/18670	0.4507	0.6329	0.4573	HLF/SKI/PPP3CA/CDON/HIVEP3/SIX1/HDAC4/SHOX2/DCN/EPHB1/PITX1/NOTCH1/ARNTL/PAX5/POPDC2/HOXD10/RB1/KCNAB1/CFLAR/MYL6B	20
BP	GO:0140056	organelle localization by membrane tethering	20/2112	169/18670	0.4507	0.6329	0.4573	CETN2/RAB8A/PLK1/TUBA4A/CDK1/PLEK/CEP135/TUBB4A/STX16/NEK2/TCTN1/STXBP2/STX4/CNTRL/STXBP1/CEP63/STX6/VTI1B/NPHP4/AHI1	20
BP	GO:0034502	protein localization to chromosome	10/2112	82/18670	0.4511	0.6331	0.4574	NDC80/PLK1/CDK1/EZH2/ATRX/TERF1/NIPBL/TTK/AURKB/RB1	10
BP	GO:0060415	muscle tissue morphogenesis	10/2112	82/18670	0.4511	0.6331	0.4574	FOXC1/ZFPM2/BMPR1A/SHOX2/TGFBR3/NOTCH1/HEY2/MYLK/S1PR1/FZD2	10
BP	GO:0022406	membrane docking	21/2112	178/18670	0.4536	0.6366	0.4599	CETN2/RAB8A/ICAM1/PLK1/TUBA4A/CDK1/PLEK/CEP135/TUBB4A/STX16/NEK2/TCTN1/STXBP2/STX4/CNTRL/STXBP1/CEP63/STX6/VTI1B/NPHP4/AHI1	21
BP	GO:0032409	regulation of transporter activity	33/2112	283/18670	0.4541	0.637	0.4603	CCR2/SRI/CACNA2D1/ANK2/FXYD1/DYSF/FXYD6/NETO2/ANXA3/GEM/KMT2A/FHL1/PLCG2/AHCYL1/NLGN1/PLN/ATP1B1/SCN1B/IFNG/RGN/ATP1A2/FGF14/P2RY6/VAMP2/PINK1/TESC/NDFIP1/PKD2/GSTO1/KCNAB1/GSTM2/CCL2/GPD1L	33
BP	GO:0043543	protein acylation	29/2112	248/18670	0.4542	0.6371	0.4603	NAP1L2/ING3/IRF4/AUTS2/BAZ1A/GATA2/CREBBP/KMT2A/SPHK1/TAF7/PCK1/RPS6KA4/LEF1/FOXO1/ARNTL/EID1/MECP2/MSL3/ZDHHC18/MBIP/KAT6B/SPI1/PHF10/RSF1/MORF4L1/CLIP3/GOLGA7/ZDHHC14/IL1B	29
BP	GO:0010874	regulation of cholesterol efflux	5/2112	39/18670	0.4558	0.6385	0.4613	ABCG1/NFKBIA/ADIPOQ/CETP/NR1H3	5
BP	GO:0019048	modulation by virus of host morphology or physiology	5/2112	39/18670	0.4558	0.6385	0.4613	DAG1/SMAD3/TYMS/KPNA2/HIPK2	5
BP	GO:0033574	response to testosterone	5/2112	39/18670	0.4558	0.6385	0.4613	AR/PLN/PSPH/RWDD1/CFLAR	5
BP	GO:0033683	nucleotide-excision repair, DNA incision	5/2112	39/18670	0.4558	0.6385	0.4613	RFC3/PARP1/CUL4B/ERCC1/GTF2H5	5
BP	GO:0042417	dopamine metabolic process	5/2112	39/18670	0.4558	0.6385	0.4613	GCH1/ITGB2/SNCAIP/MAOA/MAOB	5
BP	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	5/2112	39/18670	0.4558	0.6385	0.4613	TNFAIP3/TNFSF10/ICAM1/HGF/CFLAR	5
BP	GO:0001578	microtubule bundle formation	11/2112	91/18670	0.4559	0.6385	0.4613	TPPP3/PLK1/UBE2B/ZNF207/TTLL1/PRC1/KIF20A/SPAG16/MAP1B/SPAG1/LRRC49	11
BP	GO:0035308	negative regulation of protein dephosphorylation	8/2112	65/18670	0.4568	0.6395	0.4621	PHACTR2/PPP1R16B/PTN/NCKAP1L/MFHAS1/RGN/ENSA/PPP1R11	8
BP	GO:0051187	cofactor catabolic process	8/2112	65/18670	0.4568	0.6395	0.4621	HBB/ACAT1/GPX3/VCP/HBD/PRDX6/HP/CAT	8
BP	GO:0051236	establishment of RNA localization	23/2112	196/18670	0.459	0.6416	0.4636	RFTN1/PURA/CETN2/MX2/IGF2BP3/NUP93/CPSF6/TPR/NUP160/ZFP36L1/CETN3/THOC2/TERF1/MYO1C/DDX39A/NUP88/THOC1/ATXN2/NUP50/KHDRBS1/MVP/HNRNPA3/THOC6	23
BP	GO:2001023	regulation of response to drug	12/2112	100/18670	0.4602	0.6416	0.4636	KMT2A/HGF/ADIRF/PER2/ARL6IP5/HTR2A/PTPN11/ATP1A2/SYT17/PINK1/SNCG/FOXO3	12
BP	GO:0006379	mRNA cleavage	3/2112	22/18670	0.4608	0.6416	0.4636	RNASE4/CPSF6/CSTF2	3
BP	GO:0008053	mitochondrial fusion	3/2112	22/18670	0.4608	0.6416	0.4636	PID1/BAK1/AFG3L2	3
BP	GO:0009220	pyrimidine ribonucleotide biosynthetic process	3/2112	22/18670	0.4608	0.6416	0.4636	UPP1/NME7/NME4	3
BP	GO:0009235	cobalamin metabolic process	3/2112	22/18670	0.4608	0.6416	0.4636	CD320/CTRB2/LMBRD1	3
BP	GO:0010226	response to lithium ion	3/2112	22/18670	0.4608	0.6416	0.4636	FABP4/CEBPA/IGFBP2	3
BP	GO:0010842	retina layer formation	3/2112	22/18670	0.4608	0.6416	0.4636	TFAP2A/HIPK2/AHI1	3
BP	GO:0010866	regulation of triglyceride biosynthetic process	3/2112	22/18670	0.4608	0.6416	0.4636	SIK1/RGN/NR1H3	3
BP	GO:0010884	positive regulation of lipid storage	3/2112	22/18670	0.4608	0.6416	0.4636	CD36/ACACB/NFKB1	3
BP	GO:0021513	spinal cord dorsal/ventral patterning	3/2112	22/18670	0.4608	0.6416	0.4636	GLI3/TULP3/RFX4	3
BP	GO:0023058	adaptation of signaling pathway	3/2112	22/18670	0.4608	0.6416	0.4636	HTR2B/DNM1/APLNR	3
BP	GO:0032469	endoplasmic reticulum calcium ion homeostasis	3/2112	22/18670	0.4608	0.6416	0.4636	BAK1/TGM2/PML	3
BP	GO:0034311	diol metabolic process	3/2112	22/18670	0.4608	0.6416	0.4636	GCH1/PCBD1/SPHK1	3
BP	GO:0035584	calcium-mediated signaling using intracellular calcium source	3/2112	22/18670	0.4608	0.6416	0.4636	PTPRC/PTGFR/KDR	3
BP	GO:0044342	type B pancreatic cell proliferation	3/2112	22/18670	0.4608	0.6416	0.4636	SFRP1/IGFBP5/SERPINB1	3
BP	GO:0045117	azole transport	3/2112	22/18670	0.4608	0.6416	0.4636	ADA/BTK/LYN	3
BP	GO:0046339	diacylglycerol metabolic process	3/2112	22/18670	0.4608	0.6416	0.4636	PLCE1/DGKA/ANG	3
BP	GO:0051457	maintenance of protein location in nucleus	3/2112	22/18670	0.4608	0.6416	0.4636	SKP1/BARD1/PML	3
BP	GO:0060547	negative regulation of necrotic cell death	3/2112	22/18670	0.4608	0.6416	0.4636	BIRC3/SLC25A4/CFLAR	3
BP	GO:0060575	intestinal epithelial cell differentiation	3/2112	22/18670	0.4608	0.6416	0.4636	YIPF6/TYMS/HOXA5	3
BP	GO:0071577	zinc ion transmembrane transport	3/2112	22/18670	0.4608	0.6416	0.4636	SLC39A8/SLC39A6/SLC39A7	3
BP	GO:1903077	negative regulation of protein localization to plasma membrane	3/2112	22/18670	0.4608	0.6416	0.4636	PID1/GBP1/CSK	3
BP	GO:2000773	negative regulation of cellular senescence	3/2112	22/18670	0.4608	0.6416	0.4636	PLK2/FBXO5/AKT3	3
BP	GO:1903825	organic acid transmembrane transport	16/2112	135/18670	0.4614	0.642	0.4639	AQP9/PDPN/SLC1A3/MPC2/SLC25A22/PER2/ACACB/ARL6IP5/SLC7A5/ATP1A2/PRAF2/LRRC8D/MPC1/SLC27A5/SLC23A2/SLC5A6	16
BP	GO:1905039	carboxylic acid transmembrane transport	16/2112	135/18670	0.4614	0.642	0.4639	AQP9/PDPN/SLC1A3/MPC2/SLC25A22/PER2/ACACB/ARL6IP5/SLC7A5/ATP1A2/PRAF2/LRRC8D/MPC1/SLC27A5/SLC23A2/SLC5A6	16
BP	GO:1900006	positive regulation of dendrite development	9/2112	74/18670	0.4622	0.6431	0.4646	DLG5/LPAR1/PTPRD/ITSN1/COBL/NLGN1/EZH2/PTN/ACTR2	9
BP	GO:0006111	regulation of gluconeogenesis	6/2112	48/18670	0.4635	0.6438	0.4652	PTPN2/SIK1/FAM3C/FOXO1/LEP/ADIPOQ	6
BP	GO:0007528	neuromuscular junction development	6/2112	48/18670	0.4635	0.6438	0.4652	SIX1/ETV5/ERBB2/PTN/AFG3L2/DVL1	6
BP	GO:0007595	lactation	6/2112	48/18670	0.4635	0.6438	0.4652	CDO1/OAS2/PAM/SOCS2/PRL/CCND1	6
BP	GO:0009069	serine family amino acid metabolic process	6/2112	48/18670	0.4635	0.6438	0.4652	CDO1/SERINC3/CBS/AHCYL1/PSPH/AHCYL2	6
BP	GO:0051150	regulation of smooth muscle cell differentiation	6/2112	48/18670	0.4635	0.6438	0.4652	BMP4/SMARCD3/DNMT1/MECP2/HEY2/FGF9	6
BP	GO:0055010	ventricular cardiac muscle tissue morphogenesis	6/2112	48/18670	0.4635	0.6438	0.4652	FOXC1/ZFPM2/BMPR1A/TGFBR3/NOTCH1/HEY2	6
BP	GO:0061014	positive regulation of mRNA catabolic process	6/2112	48/18670	0.4635	0.6438	0.4652	FTO/ZFP36L1/TOB1/ZC3HAV1/ZFP36L2/PRR5L	6
BP	GO:0006367	transcription initiation from RNA polymerase II promoter	22/2112	188/18670	0.4669	0.6484	0.4685	SOX9/AR/YAP1/CREBBP/TAF7/CDK1/NOTCH1/GTF2F1/CCNB1/MECP2/HEY2/CCND1/POLR2L/GTF2A1/WWTR1/NR1H3/MED14/TP53/MED13/TEAD4/THRA/GTF2H5	22
BP	GO:0042471	ear morphogenesis	14/2112	118/18670	0.4675	0.6492	0.469	ZIC1/SOX9/SIX1/SIX2/GATA2/SOBP/SOD1/TFAP2A/FGF9/NIPBL/FZD6/DVL1/MYO3A/FZD2	14
BP	GO:0033344	cholesterol efflux	7/2112	57/18670	0.4696	0.6517	0.4709	ABCG1/NPC1/NFKBIA/ADIPOQ/CETP/NR1H3/SOAT2	7
BP	GO:0075733	intracellular transport of virus	7/2112	57/18670	0.4696	0.6517	0.4709	NUP93/TPR/NUP160/VPS37C/KPNA2/NUP88/NUP50	7
BP	GO:0000723	telomere maintenance	19/2112	162/18670	0.4701	0.6523	0.4713	PRKCQ/ZNF365/SMC6/BLM/NEK7/RFC3/NEK2/FEN1/ATRX/TERF1/HSP90AB1/PARP1/POLE2/AURKB/ERCC1/USP7/CCNE2/PARN/PML	19
BP	GO:0006363	termination of RNA polymerase I transcription	4/2112	31/18670	0.4714	0.6524	0.4714	TTF1/TAF1A/POLR2L/GTF2H5	4
BP	GO:0006482	protein demethylation	4/2112	31/18670	0.4714	0.6524	0.4714	UBE2B/JARID2/KDM7A/KDM2A	4
BP	GO:0008214	protein dealkylation	4/2112	31/18670	0.4714	0.6524	0.4714	UBE2B/JARID2/KDM7A/KDM2A	4
BP	GO:0030431	sleep	4/2112	31/18670	0.4714	0.6524	0.4714	ADA/HTR2A/PER3/IL18	4
BP	GO:0031338	regulation of vesicle fusion	4/2112	31/18670	0.4714	0.6524	0.4714	CORO1A/SPHK1/VPS16/STXBP1	4
BP	GO:0036257	multivesicular body organization	4/2112	31/18670	0.4714	0.6524	0.4714	RAB27A/VPS37C/CHMP2B/CHMP1B	4
BP	GO:0045880	positive regulation of smoothened signaling pathway	4/2112	31/18670	0.4714	0.6524	0.4714	SFRP1/DLG5/SHOX2/FGF9	4
BP	GO:0046471	phosphatidylglycerol metabolic process	4/2112	31/18670	0.4714	0.6524	0.4714	PLA2G2D/PLA2G12A/MECP2/HADHA	4
BP	GO:0050482	arachidonic acid secretion	4/2112	31/18670	0.4714	0.6524	0.4714	PLA2G2D/NMB/PLA2G12A/SYK	4
BP	GO:0050685	positive regulation of mRNA processing	4/2112	31/18670	0.4714	0.6524	0.4714	CPEB1/CCNB1/PRDX6/PAF1	4
BP	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	4/2112	31/18670	0.4714	0.6524	0.4714	CLU/CD74/BID/ACKR3	4
BP	GO:1903963	arachidonate transport	4/2112	31/18670	0.4714	0.6524	0.4714	PLA2G2D/NMB/PLA2G12A/SYK	4
BP	GO:0003205	cardiac chamber development	20/2112	171/18670	0.4726	0.6539	0.4725	BMP4/MYH10/FOXC1/ANK2/ZFPM2/BMPR1A/SHOX2/DHRS3/TGFBR3/SMARCD3/KCNK2/PARVA/CPE/RBP4/NOTCH1/HEY2/ACVR1/HEY1/FZD2/TP53	20
BP	GO:1903008	organelle disassembly	12/2112	101/18670	0.4745	0.6561	0.4741	GABARAPL1/VRK1/GOLGA2/GABARAPL2/CDK1/VCP/ATG3/ZFAND1/CTTN/PINK1/TP53/BNIP3L	12
BP	GO:0006513	protein monoubiquitination	8/2112	66/18670	0.4745	0.6561	0.4741	DTL/SKP1/UBE2B/TRIM21/FBXL2/PAF1/CUL4B/WAC	8
BP	GO:0021872	forebrain generation of neurons	8/2112	66/18670	0.4745	0.6561	0.4741	BCL11B/ASPM/GLI3/SEMA3A/INHBA/GATA2/LEF1/FEZF2	8
BP	GO:1901796	regulation of signal transduction by p53 class mediator	21/2112	180/18670	0.475	0.6566	0.4744	CD74/TPX2/TRIM24/BLM/TAF7/BARD1/TP63/RFC3/PMAIP1/RMI1/HEXIM1/CHD4/SMYD2/AURKB/HIPK2/TP53BP2/TP53/PRKAB1/AURKA/TOPBP1/PML	21
BP	GO:0022898	regulation of transmembrane transporter activity	31/2112	268/18670	0.4761	0.6571	0.4748	CCR2/SRI/CACNA2D1/ANK2/FXYD1/DYSF/FXYD6/NETO2/ANXA3/GEM/FHL1/PLCG2/AHCYL1/NLGN1/PLN/ATP1B1/SCN1B/IFNG/RGN/ATP1A2/FGF14/P2RY6/VAMP2/PINK1/TESC/PKD2/GSTO1/KCNAB1/GSTM2/CCL2/GPD1L	31
BP	GO:0006119	oxidative phosphorylation	17/2112	145/18670	0.4764	0.6571	0.4748	NDUFC1/BID/NDUFS2/COX7A1/NDUFS4/CDK1/NDUFA13/VCP/CCNB1/MECP2/SLC25A23/PINK1/NDUFA9/SDHA/NDUFB6/NDUFA4/COX7A2	17
BP	GO:0006865	amino acid transport	17/2112	145/18670	0.4764	0.6571	0.4748	SLC17A5/NTRK2/NFE2L1/NFKBIE/PDPN/SLC1A3/SLC25A22/PER2/ARL6IP5/SLC7A5/LEP/KMO/ATP1A2/PRAF2/VAMP2/STXBP1/LRRC8D	17
BP	GO:0007605	sensory perception of sound	17/2112	145/18670	0.4764	0.6571	0.4748	ALDH7A1/EYA4/SIX1/ICAM1/COCH/SOBP/SLC1A3/SOD1/FZD4/ZNF354A/NAV2/TFAP2A/CLIC5/NIPBL/MYO3A/WDR1/TBL1X	17
BP	GO:0001990	regulation of systemic arterial blood pressure by hormone	5/2112	40/18670	0.4786	0.6571	0.4748	AGTR1/OR51E2/CPA3/CYBA/REN	5
BP	GO:0006734	NADH metabolic process	5/2112	40/18670	0.4786	0.6571	0.4748	HK3/ALDOC/VCP/MDH1/TP53	5
BP	GO:0007618	mating	5/2112	40/18670	0.4786	0.6571	0.4748	HDAC4/ADA/TAC1/EDNRB/THRA	5
BP	GO:0021532	neural tube patterning	5/2112	40/18670	0.4786	0.6571	0.4748	BMP4/LRP6/GLI3/TCTN1/TULP3	5
BP	GO:0035315	hair cell differentiation	5/2112	40/18670	0.4786	0.6571	0.4748	SOD1/NOTCH1/HEY2/SPINK5/MYCL	5
BP	GO:0046621	negative regulation of organ growth	5/2112	40/18670	0.4786	0.6571	0.4748	MEIS1/KCNK2/RBP4/PAK1/JARID2	5
BP	GO:0072583	clathrin-dependent endocytosis	5/2112	40/18670	0.4786	0.6571	0.4748	ITGA4/GAK/WASL/FNBP1L/SH3GL3	5
BP	GO:0098534	centriole assembly	5/2112	40/18670	0.4786	0.6571	0.4748	CETN2/CEP135/PLK2/CEP63/STIL	5
BP	GO:2000008	regulation of protein localization to cell surface	5/2112	40/18670	0.4786	0.6571	0.4748	CD247/HSP90AB1/STX4/HFE/GPD1L	5
BP	GO:0017156	calcium ion regulated exocytosis	18/2112	154/18670	0.4789	0.6571	0.4748	PREPL/PRKCB/PFN2/ARHGAP17/NLGN1/HTR2A/CHRNA5/NOTCH1/SYT17/STX4/VAMP2/STXBP1/BACE1/SDF4/DVL1/CASK/P2RY4/CADPS	18
BP	GO:0072376	protein activation cascade	23/2112	198/18670	0.4794	0.6571	0.4748	TRBC1/SCARA3/CLU/FCN1/CFP/PROS1/CR1/IGHM/IGLL5/CFD/CD19/IGLC1/IGLV1-44/C7/IGHG1/FBLN1/TFPI/CFB/CD81/GP1BA/IL1B/CR2/C6	23
BP	GO:0003128	heart field specification	2/2112	14/18670	0.4812	0.6571	0.4748	BMP4/SMARCD3	2
BP	GO:0006241	CTP biosynthetic process	2/2112	14/18670	0.4812	0.6571	0.4748	NME7/NME4	2
BP	GO:0006896	Golgi to vacuole transport	2/2112	14/18670	0.4812	0.6571	0.4748	GAK/VTI1B	2
BP	GO:0006999	nuclear pore organization	2/2112	14/18670	0.4812	0.6571	0.4748	NUP93/TPR	2
BP	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity	2/2112	14/18670	0.4812	0.6571	0.4748	GPRC5A/ZGPAT	2
BP	GO:0009071	serine family amino acid catabolic process	2/2112	14/18670	0.4812	0.6571	0.4748	CDO1/CBS	2
BP	GO:0010867	positive regulation of triglyceride biosynthetic process	2/2112	14/18670	0.4812	0.6571	0.4748	RGN/NR1H3	2
BP	GO:0010989	negative regulation of low-density lipoprotein particle clearance	2/2112	14/18670	0.4812	0.6571	0.4748	CSK/MYLIP	2
BP	GO:0018410	C-terminal protein amino acid modification	2/2112	14/18670	0.4812	0.6571	0.4748	ICMT/FOLH1	2
BP	GO:0021535	cell migration in hindbrain	2/2112	14/18670	0.4812	0.6571	0.4748	RBFOX2/LEF1	2
BP	GO:0031937	positive regulation of chromatin silencing	2/2112	14/18670	0.4812	0.6571	0.4748	DNMT1/MPHOSPH8	2
BP	GO:0032048	cardiolipin metabolic process	2/2112	14/18670	0.4812	0.6571	0.4748	MECP2/HADHA	2
BP	GO:0035435	phosphate ion transmembrane transport	2/2112	14/18670	0.4812	0.6571	0.4748	ANKH/SLC37A1	2
BP	GO:0035791	platelet-derived growth factor receptor-beta signaling pathway	2/2112	14/18670	0.4812	0.6571	0.4748	PTPN2/PDGFRL	2
BP	GO:0042487	regulation of odontogenesis of dentin-containing tooth	2/2112	14/18670	0.4812	0.6571	0.4748	BMP4/TNFRSF11B	2
BP	GO:0042574	retinal metabolic process	2/2112	14/18670	0.4812	0.6571	0.4748	AKR1C3/AKR1C1	2
BP	GO:0044090	positive regulation of vacuole organization	2/2112	14/18670	0.4812	0.6571	0.4748	PIP4K2B/PIP4K2A	2
BP	GO:0045651	positive regulation of macrophage differentiation	2/2112	14/18670	0.4812	0.6571	0.4748	HCLS1/RB1	2
BP	GO:0045836	positive regulation of meiotic nuclear division	2/2112	14/18670	0.4812	0.6571	0.4748	UBE2B/DAZL	2
BP	GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	2/2112	14/18670	0.4812	0.6571	0.4748	APOBEC3G/MPHOSPH8	2
BP	GO:0046036	CTP metabolic process	2/2112	14/18670	0.4812	0.6571	0.4748	NME7/NME4	2
BP	GO:0046606	negative regulation of centrosome cycle	2/2112	14/18670	0.4812	0.6571	0.4748	NEK2/CCNF	2
BP	GO:0046855	inositol phosphate dephosphorylation	2/2112	14/18670	0.4812	0.6571	0.4748	INPP1/MTMR2	2
BP	GO:0046940	nucleoside monophosphate phosphorylation	2/2112	14/18670	0.4812	0.6571	0.4748	AK1/AK6	2
BP	GO:0050667	homocysteine metabolic process	2/2112	14/18670	0.4812	0.6571	0.4748	CBS/NOX4	2
BP	GO:0050720	interleukin-1 beta biosynthetic process	2/2112	14/18670	0.4812	0.6571	0.4748	JAK2/IFNG	2
BP	GO:0060049	regulation of protein glycosylation	2/2112	14/18670	0.4812	0.6571	0.4748	IL15/GOLGA2	2
BP	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning	2/2112	14/18670	0.4812	0.6571	0.4748	GLI3/TULP3	2
BP	GO:0060911	cardiac cell fate commitment	2/2112	14/18670	0.4812	0.6571	0.4748	ACVR1/TENM4	2
BP	GO:0071361	cellular response to ethanol	2/2112	14/18670	0.4812	0.6571	0.4748	CCL7/SPI1	2
BP	GO:0071391	cellular response to estrogen stimulus	2/2112	14/18670	0.4812	0.6571	0.4748	SFRP1/TRIM24	2
BP	GO:0086069	bundle of His cell to Purkinje myocyte communication	2/2112	14/18670	0.4812	0.6571	0.4748	CACNA2D1/DSC2	2
BP	GO:0090110	cargo loading into COPII-coated vesicle	2/2112	14/18670	0.4812	0.6571	0.4748	SEC31A/SEC23B	2
BP	GO:0090128	regulation of synapse maturation	2/2112	14/18670	0.4812	0.6571	0.4748	CLSTN1/CDC20	2
BP	GO:0099188	postsynaptic cytoskeleton organization	2/2112	14/18670	0.4812	0.6571	0.4748	MYH10/WASF2	2
BP	GO:1901070	guanosine-containing compound biosynthetic process	2/2112	14/18670	0.4812	0.6571	0.4748	NME7/NME4	2
BP	GO:1901386	negative regulation of voltage-gated calcium channel activity	2/2112	14/18670	0.4812	0.6571	0.4748	DYSF/GEM	2
BP	GO:1901626	regulation of postsynaptic membrane organization	2/2112	14/18670	0.4812	0.6571	0.4748	PTN/CDH2	2
BP	GO:1902656	calcium ion import into cytosol	2/2112	14/18670	0.4812	0.6571	0.4748	CACNA2D1/MS4A1	2
BP	GO:1905651	regulation of artery morphogenesis	2/2112	14/18670	0.4812	0.6571	0.4748	NOTCH1/AKT3	2
BP	GO:0006368	transcription elongation from RNA polymerase II promoter	10/2112	84/18670	0.4825	0.6587	0.4759	CCNT1/EZH2/ADRM1/ZMYND11/BRD4/GTF2F1/POLR2L/PAF1/EAF2/GTF2H5	10
BP	GO:0010595	positive regulation of endothelial cell migration	15/2112	128/18670	0.4834	0.6598	0.4767	BMP4/FGF18/ANGPT1/ITGB1BP1/CD40/PRKD2/ANXA3/GATA2/FGF2/SP1/PLK2/HSPB1/AKT3/PRKD1/KDR	15
BP	GO:0003044	regulation of systemic arterial blood pressure mediated by a chemical signal	6/2112	49/18670	0.4841	0.6606	0.4773	AGTR1/OR51E2/CPA3/CYBA/REN/SLC2A5	6
BP	GO:0010565	regulation of cellular ketone metabolic process	21/2112	181/18670	0.4857	0.6624	0.4786	PSMB9/PSMB8/NQO1/PSMB10/AKR1C3/ACADVL/NFE2L1/CD74/PSME1/ERLIN1/ACACB/RGN/ADIPOQ/ERLIN2/FABP5/PDK4/NR1H3/ACADL/DKK3/IL1B/ELOVL5	21
BP	GO:0003073	regulation of systemic arterial blood pressure	11/2112	93/18670	0.4857	0.6624	0.4786	EMP2/AR/CORO2B/NAV2/AGTR1/OR51E2/MECP2/CPA3/CYBA/REN/SLC2A5	11
BP	GO:0007589	body fluid secretion	11/2112	93/18670	0.4857	0.6624	0.4786	CDO1/OAS2/PAM/ADA/TAC1/SOCS2/PRL/CCND1/NR1H3/CYBA/NPR3	11
BP	GO:0061951	establishment of protein localization to plasma membrane	7/2112	58/18670	0.4884	0.6659	0.4812	CSK/PREPL/RAB8A/BBS1/VAMP2/GOLGA7/SPTBN1	7
BP	GO:0015837	amine transport	12/2112	102/18670	0.4887	0.666	0.4812	AQP9/SLC18A2/PER2/ARL6IP5/HTR2A/LEP/KMO/ATP1A2/SYT17/STXBP1/PINK1/SNCG	12
BP	GO:0030148	sphingolipid biosynthetic process	12/2112	102/18670	0.4887	0.666	0.4812	ALDH3A2/SGPL1/PRKD2/SPHK1/FA2H/SGMS1/ELOVL4/PRKD1/ELOVL2/UGCG/ELOVL5/CERS4	12
BP	GO:0000715	nucleotide-excision repair, DNA damage recognition	3/2112	23/18670	0.4912	0.6667	0.4817	CETN2/PARP1/CUL4B	3
BP	GO:0007530	sex determination	3/2112	23/18670	0.4912	0.6667	0.4817	SOX9/AR/FGF9	3
BP	GO:0009147	pyrimidine nucleoside triphosphate metabolic process	3/2112	23/18670	0.4912	0.6667	0.4817	NME7/TYMS/NME4	3
BP	GO:0010447	response to acidic pH	3/2112	23/18670	0.4912	0.6667	0.4817	PCK1/GPR65/GPR4	3
BP	GO:0010499	proteasomal ubiquitin-independent protein catabolic process	3/2112	23/18670	0.4912	0.6667	0.4817	PSMB9/PSMB8/PSMB10	3
BP	GO:0010528	regulation of transposition	3/2112	23/18670	0.4912	0.6667	0.4817	APOBEC3G/APOBEC3B/MYBL1	3
BP	GO:0010529	negative regulation of transposition	3/2112	23/18670	0.4912	0.6667	0.4817	APOBEC3G/APOBEC3B/MYBL1	3
BP	GO:0015740	C4-dicarboxylate transport	3/2112	23/18670	0.4912	0.6667	0.4817	SLC1A3/SLC25A22/LRRC8D	3
BP	GO:0022410	circadian sleep/wake cycle process	3/2112	23/18670	0.4912	0.6667	0.4817	ADA/NLGN1/PER3	3
BP	GO:0032717	negative regulation of interleukin-8 production	3/2112	23/18670	0.4912	0.6667	0.4817	PTPN22/ANXA4/TLR6	3
BP	GO:0032799	low-density lipoprotein receptor particle metabolic process	3/2112	23/18670	0.4912	0.6667	0.4817	MYLIP/ADIPOQ/ITGAV	3
BP	GO:0050995	negative regulation of lipid catabolic process	3/2112	23/18670	0.4912	0.6667	0.4817	ACACB/PDE3B/IL1B	3
BP	GO:0051004	regulation of lipoprotein lipase activity	3/2112	23/18670	0.4912	0.6667	0.4817	ANGPTL4/NR1H3/LIPC	3
BP	GO:0051350	negative regulation of lyase activity	3/2112	23/18670	0.4912	0.6667	0.4817	CCR2/EDNRB/NPR3	3
BP	GO:0051589	negative regulation of neurotransmitter transport	3/2112	23/18670	0.4912	0.6667	0.4817	ARL6IP5/MAOB/LILRB1	3
BP	GO:0061436	establishment of skin barrier	3/2112	23/18670	0.4912	0.6667	0.4817	FA2H/TP63/UGCG	3
BP	GO:0071425	hematopoietic stem cell proliferation	3/2112	23/18670	0.4912	0.6667	0.4817	KITLG/PIM1/ETV6	3
BP	GO:2000637	positive regulation of gene silencing by miRNA	3/2112	23/18670	0.4912	0.6667	0.4817	BMP4/EGFR/TP53	3
BP	GO:0003143	embryonic heart tube morphogenesis	8/2112	67/18670	0.4921	0.6677	0.4824	YAP1/SMAD3/NOTCH1/ACVR1/MEGF8/PKD2/STIL/AHI1	8
BP	GO:0046365	monosaccharide catabolic process	8/2112	67/18670	0.4921	0.6677	0.4824	GALT/HK3/ALDOC/LRP5/FUT8/TP53/TKTL1/FUT4	8
BP	GO:0006721	terpenoid metabolic process	14/2112	120/18670	0.4938	0.6698	0.484	GPC5/ALDH3A2/AKR1C3/ADH1C/AKR1B1/EGFR/DHRS3/AKR1C1/RBP4/ADH1B/GPC4/ADH5/DHRS9/RETSAT	14
BP	GO:0001975	response to amphetamine	4/2112	32/18670	0.497	0.6727	0.486	PPP3CA/ICAM1/SLC18A2/SOD1	4
BP	GO:0002323	natural killer cell activation involved in immune response	4/2112	32/18670	0.497	0.6727	0.486	CORO1A/HLA-F/RAB27A/IFNA1	4
BP	GO:0015012	heparan sulfate proteoglycan biosynthetic process	4/2112	32/18670	0.497	0.6727	0.486	EXTL2/TCF7L2/UGDH/EXT2	4
BP	GO:0042311	vasodilation	4/2112	32/18670	0.497	0.6727	0.486	GCH1/SOD1/EDNRB/PRKG1	4
BP	GO:0042491	inner ear auditory receptor cell differentiation	4/2112	32/18670	0.497	0.6727	0.486	SOD1/NOTCH1/HEY2/MYCL	4
BP	GO:0042573	retinoic acid metabolic process	4/2112	32/18670	0.497	0.6727	0.486	AKR1C3/ADH1C/ADH1B/DHRS9	4
BP	GO:0050779	RNA destabilization	4/2112	32/18670	0.497	0.6727	0.486	FTO/TNFRSF1B/ZFP36L1/ZFP36L2	4
BP	GO:0060674	placenta blood vessel development	4/2112	32/18670	0.497	0.6727	0.486	HEY2/FOSL1/HEY1/PKD2	4
BP	GO:0090504	epiboly	4/2112	32/18670	0.497	0.6727	0.486	PDPN/HBEGF/MEGF8/MMP12	4
BP	GO:1902235	regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	4/2112	32/18670	0.497	0.6727	0.486	SERINC3/PTPN2/PMAIP1/DDIT3	4
BP	GO:1901532	regulation of hematopoietic progenitor cell differentiation	10/2112	85/18670	0.4981	0.6738	0.4868	PSMB9/KITLG/PSMB8/PSMB10/FOXC1/YAP1/GATA2/PSME1/KMT2A/NOTCH1	10
BP	GO:0042594	response to starvation	22/2112	191/18670	0.4981	0.6738	0.4868	SFRP1/GABARAPL1/AKR1C3/OXCT1/UPP1/TBC1D5/GABARAPL2/DAP/SIK1/ACAT1/PCK1/PMAIP1/FOXO1/HIGD1A/DSC2/PDK4/HFE/DDIT3/FOXO3/PRKD1/SESN1/TP53	22
BP	GO:0009308	amine metabolic process	16/2112	138/18670	0.4981	0.6738	0.4868	PSMB9/PSMB8/IDO1/NQO1/ALDH7A1/PSMB10/KYNU/ITGB2/PSME1/MAOA/KMO/MECP2/AOC2/MAOB/NAAA/AOC3	16
BP	GO:0034765	regulation of ion transmembrane transport	55/2112	483/18670	0.5009	0.6767	0.4889	CXCL9/XCL1/CCR2/CORO1A/SRI/CACNA2D1/ANK2/TCIRG1/FXYD1/DYSF/FXYD6/NETO2/ANXA3/GEM/CXCL10/KCNJ5/PTPN6/SLC31A2/FHL1/PLCG2/AHCYL1/NLGN1/PLN/PER2/KCNJ15/KCNJ2/ARL6IP5/TRPC1/CD19/ATP1B1/SCN1B/KCNJ8/IFNG/RGN/ATP1A2/CXCL11/SLC8A1/FGF14/P2RY6/APLNR/CLIC5/VAMP2/CRBN/PINK1/TESC/CYBA/LYN/PKD2/GSTO1/KCNAB1/WDR1/GSTM2/CCL2/SNTA1/GPD1L	55
BP	GO:0010955	negative regulation of protein processing	5/2112	41/18670	0.5011	0.6767	0.4889	GAS1/BIRC3/CST7/CR1/GLG1	5
BP	GO:0019432	triglyceride biosynthetic process	5/2112	41/18670	0.5011	0.6767	0.4889	GK/SIK1/PCK1/RGN/NR1H3	5
BP	GO:0040019	positive regulation of embryonic development	5/2112	41/18670	0.5011	0.6767	0.4889	IGF1/AR/SIX1/DAG1/TENM4	5
BP	GO:0061028	establishment of endothelial barrier	5/2112	41/18670	0.5011	0.6767	0.4889	ICAM1/PPP1R16B/PTPRS/IL1B/CDH5	5
BP	GO:0098927	vesicle-mediated transport between endosomal compartments	5/2112	41/18670	0.5011	0.6767	0.4889	CORO1A/EMP2/HOOK2/KIF16B/MTMR2	5
BP	GO:1900117	regulation of execution phase of apoptosis	5/2112	41/18670	0.5011	0.6767	0.4889	DLC1/APAF1/IL6/TP53BP2/TP53	5
BP	GO:1903318	negative regulation of protein maturation	5/2112	41/18670	0.5011	0.6767	0.4889	GAS1/BIRC3/CST7/CR1/GLG1	5
BP	GO:0045216	cell-cell junction organization	18/2112	156/18670	0.502	0.6776	0.4896	PRKCH/DLG5/CDH19/PARD3/ANK2/CDH2/SMAD3/CD9/ECT2/PECAM1/MYO1C/TGFB3/MPP5/GJC1/WDR1/LIMS2/NPHP4/CDH5	18
BP	GO:0018958	phenol-containing compound metabolic process	12/2112	103/18670	0.5028	0.6786	0.4903	FAH/GCH1/ITGB2/DIO2/SNCAIP/AKR1B1/MAOA/TRPC1/CPQ/AOC2/MAOB/DIO3	12
BP	GO:0015849	organic acid transport	38/2112	333/18670	0.5031	0.6788	0.4904	PLA2G2D/SLC17A5/NTRK2/NFE2L1/ABCC4/AQP9/NFKBIE/SLC26A2/CD36/SLC16A4/PDPN/SLC16A2/AKR1C1/SLC1A3/MPC2/NMB/SLC25A22/PER2/PLA2G12A/ACACB/ARL6IP5/SLC7A5/LEP/STARD5/KMO/ATP1A2/PRAF2/SYK/VAMP2/STXBP1/LRRC8D/MPC1/FABP4/SLC27A5/SLC23A2/SLCO1C1/SLC5A6/IL1B	38
BP	GO:0046942	carboxylic acid transport	38/2112	333/18670	0.5031	0.6788	0.4904	PLA2G2D/SLC17A5/NTRK2/NFE2L1/ABCC4/AQP9/NFKBIE/SLC26A2/CD36/SLC16A4/PDPN/SLC16A2/AKR1C1/SLC1A3/MPC2/NMB/SLC25A22/PER2/PLA2G12A/ACACB/ARL6IP5/SLC7A5/LEP/STARD5/KMO/ATP1A2/PRAF2/SYK/VAMP2/STXBP1/LRRC8D/MPC1/FABP4/SLC27A5/SLC23A2/SLCO1C1/SLC5A6/IL1B	38
BP	GO:0042398	cellular modified amino acid biosynthetic process	6/2112	50/18670	0.5044	0.6802	0.4915	GCH1/ALDH7A1/CNDP2/PTDSS1/PLSCR1/HAGH	6
BP	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	6/2112	50/18670	0.5044	0.6802	0.4915	CCND2/EGFR/CDC45/HYAL1/CCND1/CUL4B	6
BP	GO:0000041	transition metal ion transport	13/2112	112/18670	0.5049	0.6803	0.4915	SCO2/TCIRG1/CP/TFRC/SLC31A2/CUTC/SLC39A8/TRPC1/IFNG/HFE/SLC39A6/SLC39A7/ATP6V1B2	13
BP	GO:0002065	columnar/cuboidal epithelial cell differentiation	13/2112	112/18670	0.5049	0.6803	0.4915	BMP4/TMEM231/YIPF6/CDH2/TP63/SOD1/LEF1/NOTCH1/ARNTL/HEY2/TYMS/HOXA5/MYCL	13
BP	GO:0006354	DNA-templated transcription, elongation	13/2112	112/18670	0.5049	0.6803	0.4915	CCNT1/TCEA2/EZH2/ADRM1/ZMYND11/TAF1A/BRD4/GTF2F1/POLR2L/PAF1/THOC1/EAF2/GTF2H5	13
BP	GO:0017158	regulation of calcium ion-dependent exocytosis	13/2112	112/18670	0.5049	0.6803	0.4915	PREPL/PRKCB/PFN2/NLGN1/HTR2A/CHRNA5/NOTCH1/SYT17/STXBP1/BACE1/DVL1/CASK/P2RY4	13
BP	GO:0010656	negative regulation of muscle cell apoptotic process	7/2112	59/18670	0.5071	0.6829	0.4934	LRP6/IGF1/JAK2/DNMT1/HEY2/HSPB6/CFLAR	7
BP	GO:0097755	positive regulation of blood vessel diameter	7/2112	59/18670	0.5071	0.6829	0.4934	GCH1/EGFR/SOD1/LEP/EDNRB/PRKG1/EPHX2	7
BP	GO:1902369	negative regulation of RNA catabolic process	7/2112	59/18670	0.5071	0.6829	0.4934	MYD88/HNRNPA0/DAZL/TOB1/MAPKAPK2/NBAS/PARN	7
BP	GO:0046323	glucose import	8/2112	68/18670	0.5095	0.6859	0.4956	ENPP1/PID1/PIK3R1/IGF1/PTPN11/LEP/ADIPOQ/SORBS1	8
BP	GO:0035050	embryonic heart tube development	9/2112	77/18670	0.5116	0.6886	0.4975	FOXC1/YAP1/SMAD3/NOTCH1/ACVR1/MEGF8/PKD2/STIL/AHI1	9
BP	GO:0051592	response to calcium ion	17/2112	148/18670	0.5119	0.6888	0.4977	CPNE3/PENK/AKR1C3/PPP3CA/EGFR/SEC31A/AHCYL1/NLGN1/TRPC1/ECT2/GDI1/SYT17/CCND1/SLC25A23/RYR3/GUCA1A/PKD2	17
BP	GO:0043271	negative regulation of ion transport	18/2112	157/18670	0.5134	0.6907	0.499	LILRB2/SRI/ICAM1/DYSF/GEM/PLN/ARL6IP5/HTR2A/LEP/ATP1A2/CRBN/MAOB/PKD2/GSTO1/KCNAB1/GSTM2/LILRB1/PRKG2	18
BP	GO:0060291	long-term synaptic potentiation	10/2112	86/18670	0.5135	0.6907	0.499	LILRB2/NTRK2/NLGN1/CX3CR1/PTN/PLK2/MECP2/STX4/VAMP2/CYP46A1	10
BP	GO:0070646	protein modification by small protein removal	34/2112	299/18670	0.5146	0.6918	0.4999	TRAF3/PSMB9/TNFAIP3/UCHL1/PSMB8/BIRC3/PSMB10/USP11/AR/USP46/TNIP2/IFIH1/PSME1/USP3/BARD1/CDK1/VCPIP1/CCNA2/NFKBIA/DDX58/TRIM21/ADRM1/SMAD3/UBE2D1/VCP/IKBKG/ACTR8/TNIP3/CDC20/USP10/TP53/USP7/DESI2/NLRP3	34
BP	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	11/2112	95/18670	0.5152	0.6918	0.4999	PSMB9/PSMB8/PSMB10/SKP1/PSME1/FBXL2/WWTR1/CUL2/CUL4B/FBXL7/CCNF	11
BP	GO:2000060	positive regulation of ubiquitin-dependent protein catabolic process	11/2112	95/18670	0.5152	0.6918	0.4999	CLU/CBFA2T3/PLK1/CHFR/PLK2/VCP/RNF19B/CEBPA/DVL1/AURKA/RNF14	11
BP	GO:0006956	complement activation	20/2112	175/18670	0.5162	0.6918	0.4999	TRBC1/SCARA3/CLU/FCN1/CFP/PROS1/CR1/IGHM/IGLL5/CFD/CD19/IGLC1/IGLV1-44/C7/IGHG1/CFB/CD81/IL1B/CR2/C6	20
BP	GO:0001523	retinoid metabolic process	12/2112	104/18670	0.5168	0.6918	0.4999	GPC5/AKR1C3/ADH1C/AKR1B1/DHRS3/AKR1C1/RBP4/ADH1B/GPC4/ADH5/DHRS9/RETSAT	12
BP	GO:0050657	nucleic acid transport	22/2112	193/18670	0.5188	0.6918	0.4999	RFTN1/PURA/CETN2/MX2/IGF2BP3/NUP93/CPSF6/TPR/NUP160/ZFP36L1/CETN3/THOC2/MYO1C/DDX39A/NUP88/THOC1/ATXN2/NUP50/KHDRBS1/MVP/HNRNPA3/THOC6	22
BP	GO:0050658	RNA transport	22/2112	193/18670	0.5188	0.6918	0.4999	RFTN1/PURA/CETN2/MX2/IGF2BP3/NUP93/CPSF6/TPR/NUP160/ZFP36L1/CETN3/THOC2/MYO1C/DDX39A/NUP88/THOC1/ATXN2/NUP50/KHDRBS1/MVP/HNRNPA3/THOC6	22
BP	GO:0001711	endodermal cell fate commitment	2/2112	15/18670	0.5189	0.6918	0.4999	SOX2/PAF1	2
BP	GO:0001829	trophectodermal cell differentiation	2/2112	15/18670	0.5189	0.6918	0.4999	HOPX/ADA	2
BP	GO:0006000	fructose metabolic process	2/2112	15/18670	0.5189	0.6918	0.4999	AKR1B1/ALDOC	2
BP	GO:0006390	mitochondrial transcription	2/2112	15/18670	0.5189	0.6918	0.4999	TFAM/FOXO3	2
BP	GO:0007039	protein catabolic process in the vacuole	2/2112	15/18670	0.5189	0.6918	0.4999	TCIRG1/CD81	2
BP	GO:0007512	adult heart development	2/2112	15/18670	0.5189	0.6918	0.4999	MYH10/APLNR	2
BP	GO:0009109	coenzyme catabolic process	2/2112	15/18670	0.5189	0.6918	0.4999	ACAT1/VCP	2
BP	GO:0009209	pyrimidine ribonucleoside triphosphate biosynthetic process	2/2112	15/18670	0.5189	0.6918	0.4999	NME7/NME4	2
BP	GO:0030730	sequestering of triglyceride	2/2112	15/18670	0.5189	0.6918	0.4999	ENPP1/IL1B	2
BP	GO:0032105	negative regulation of response to extracellular stimulus	2/2112	15/18670	0.5189	0.6918	0.4999	KANK2/LEP	2
BP	GO:0032108	negative regulation of response to nutrient levels	2/2112	15/18670	0.5189	0.6918	0.4999	KANK2/LEP	2
BP	GO:0032274	gonadotropin secretion	2/2112	15/18670	0.5189	0.6918	0.4999	INHBA/LEP	2
BP	GO:0032486	Rap protein signal transduction	2/2112	15/18670	0.5189	0.6918	0.4999	TIMP2/PLK2	2
BP	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase	2/2112	15/18670	0.5189	0.6918	0.4999	ACOX2/ECI2	2
BP	GO:0035067	negative regulation of histone acetylation	2/2112	15/18670	0.5189	0.6918	0.4999	TAF7/SPI1	2
BP	GO:0042559	pteridine-containing compound biosynthetic process	2/2112	15/18670	0.5189	0.6918	0.4999	GCH1/PCBD1	2
BP	GO:0042754	negative regulation of circadian rhythm	2/2112	15/18670	0.5189	0.6918	0.4999	ADA/PER2	2
BP	GO:0042762	regulation of sulfur metabolic process	2/2112	15/18670	0.5189	0.6918	0.4999	SP1/PDK4	2
BP	GO:0042921	glucocorticoid receptor signaling pathway	2/2112	15/18670	0.5189	0.6918	0.4999	LMO3/ARNTL	2
BP	GO:0043249	erythrocyte maturation	2/2112	15/18670	0.5189	0.6918	0.4999	TRIM58/PTBP3	2
BP	GO:0043508	negative regulation of JUN kinase activity	2/2112	15/18670	0.5189	0.6918	0.4999	SFRP1/PTPN22	2
BP	GO:0045360	regulation of interleukin-1 biosynthetic process	2/2112	15/18670	0.5189	0.6918	0.4999	JAK2/IFNG	2
BP	GO:0045838	positive regulation of membrane potential	2/2112	15/18670	0.5189	0.6918	0.4999	BID/VCP	2
BP	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly	2/2112	15/18670	0.5189	0.6918	0.4999	TP53/THRA	2
BP	GO:0046838	phosphorylated carbohydrate dephosphorylation	2/2112	15/18670	0.5189	0.6918	0.4999	INPP1/MTMR2	2
BP	GO:0048368	lateral mesoderm development	2/2112	15/18670	0.5189	0.6918	0.4999	BMPR1A/YAP1	2
BP	GO:0051883	killing of cells in other organism involved in symbiotic interaction	2/2112	15/18670	0.5189	0.6918	0.4999	KRT6A/CXCL6	2
BP	GO:0060134	prepulse inhibition	2/2112	15/18670	0.5189	0.6918	0.4999	BACE1/DVL1	2
BP	GO:0070365	hepatocyte differentiation	2/2112	15/18670	0.5189	0.6918	0.4999	E2F8/PCK1	2
BP	GO:0098840	protein transport along microtubule	2/2112	15/18670	0.5189	0.6918	0.4999	PURA/HSPB1	2
BP	GO:0099118	microtubule-based protein transport	2/2112	15/18670	0.5189	0.6918	0.4999	PURA/HSPB1	2
BP	GO:1900037	regulation of cellular response to hypoxia	2/2112	15/18670	0.5189	0.6918	0.4999	KCNK2/PINK1	2
BP	GO:1902188	positive regulation of viral release from host cell	2/2112	15/18670	0.5189	0.6918	0.4999	PC/CHMP2B	2
BP	GO:0003418	growth plate cartilage chondrocyte differentiation	3/2112	24/18670	0.5206	0.6918	0.4999	SCARA3/COCH/COL14A1	3
BP	GO:0003433	chondrocyte development involved in endochondral bone morphogenesis	3/2112	24/18670	0.5206	0.6918	0.4999	SCARA3/COCH/COL14A1	3
BP	GO:0007141	male meiosis I	3/2112	24/18670	0.5206	0.6918	0.4999	MYBL1/REC8/TRIP13	3
BP	GO:0018126	protein hydroxylation	3/2112	24/18670	0.5206	0.6918	0.4999	CRTAP/ASPH/P4HTM	3
BP	GO:0021511	spinal cord patterning	3/2112	24/18670	0.5206	0.6918	0.4999	GLI3/TULP3/RFX4	3
BP	GO:0021544	subpallium development	3/2112	24/18670	0.5206	0.6918	0.4999	BCL11B/GLI3/INHBA	3
BP	GO:0034629	cellular protein-containing complex localization	3/2112	24/18670	0.5206	0.6918	0.4999	WASL/SGCD/KLHL21	3
BP	GO:0042430	indole-containing compound metabolic process	3/2112	24/18670	0.5206	0.6918	0.4999	IDO1/KYNU/KMO	3
BP	GO:0046174	polyol catabolic process	3/2112	24/18670	0.5206	0.6918	0.4999	GK/INPP1/MTMR2	3
BP	GO:0046835	carbohydrate phosphorylation	3/2112	24/18670	0.5206	0.6918	0.4999	HK3/NAGK/FGGY	3
BP	GO:0051446	positive regulation of meiotic cell cycle	3/2112	24/18670	0.5206	0.6918	0.4999	UBE2B/CDC25B/DAZL	3
BP	GO:0060148	positive regulation of posttranscriptional gene silencing	3/2112	24/18670	0.5206	0.6918	0.4999	BMP4/EGFR/TP53	3
BP	GO:1903010	regulation of bone development	3/2112	24/18670	0.5206	0.6918	0.4999	GLI3/RGN/LILRB1	3
BP	GO:1903421	regulation of synaptic vesicle recycling	3/2112	24/18670	0.5206	0.6918	0.4999	DNM1/NLGN1/FGF14	3
BP	GO:1904376	negative regulation of protein localization to cell periphery	3/2112	24/18670	0.5206	0.6918	0.4999	PID1/GBP1/CSK	3
BP	GO:0010737	protein kinase A signaling	4/2112	33/18670	0.522	0.6918	0.4999	LCP1/AKAP12/ADIPOQ/AKAP1	4
BP	GO:0014072	response to isoquinoline alkaloid	4/2112	33/18670	0.522	0.6918	0.4999	PENK/CXCR4/ADA/TAC1	4
BP	GO:0016486	peptide hormone processing	4/2112	33/18670	0.522	0.6918	0.4999	CPE/CPA3/REN/PCSK7	4
BP	GO:0031112	positive regulation of microtubule polymerization or depolymerization	4/2112	33/18670	0.522	0.6918	0.4999	MECP2/TERF1/PAK1/MAP1B	4
BP	GO:0036003	positive regulation of transcription from RNA polymerase II promoter in response to stress	4/2112	33/18670	0.522	0.6918	0.4999	NOTCH1/DDIT3/MBTPS2/TP53	4
BP	GO:0043278	response to morphine	4/2112	33/18670	0.522	0.6918	0.4999	PENK/CXCR4/ADA/TAC1	4
BP	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	4/2112	33/18670	0.522	0.6918	0.4999	DDX6/LSM3/EXOSC7/LSM5	4
BP	GO:0048011	neurotrophin TRK receptor signaling pathway	4/2112	33/18670	0.522	0.6918	0.4999	NDN/NTRK2/CYFIP2/PTPN11	4
BP	GO:0048821	erythrocyte development	4/2112	33/18670	0.522	0.6918	0.4999	NCKAP1L/TRIM58/SH2B3/PTBP3	4
BP	GO:0048854	brain morphogenesis	4/2112	33/18670	0.522	0.6918	0.4999	CDH2/AKT3/FZD6/FOXO3	4
BP	GO:2000758	positive regulation of peptidyl-lysine acetylation	4/2112	33/18670	0.522	0.6918	0.4999	NAP1L2/AUTS2/RPS6KA4/IL1B	4
BP	GO:2001024	negative regulation of response to drug	4/2112	33/18670	0.522	0.6918	0.4999	HGF/ARL6IP5/PTPN11/PINK1	4
BP	GO:2001038	regulation of cellular response to drug	4/2112	33/18670	0.522	0.6918	0.4999	KMT2A/HGF/PINK1/FOXO3	4
CC	GO:0009897	external side of plasma membrane	100/2169	393/19717	3.993e-16	2.871e-13	2.404e-13	CD3D/IL2RG/CXCL9/TRBC1/CCR5/CD3E/PTPRC/CTLA4/CD2/CRLF1/CCR2/IL27RA/TLR8/HLA-F/CD8A/HLA-A/CXCR4/IL2RB/FCN1/SERPINA5/IL3RA/IL7R/IL11RA/HLA-C/MS4A2/CCR7/ABCG1/ANTXR1/CD74/ITGB2/CD3G/CD5/HLA-G/ICAM1/ACKR3/BMPR1A/CD36/CD40/MICB/TNFRSF14/CXCL10/TFRC/BTN2A2/HLA-E/ADA/KCNJ5/DAG1/TGFBR3/IGHM/IGLL5/HLA-B/GHR/CD69/CD226/CCR1/PDCD1LG2/NLGN1/IL13RA2/CX3CR1/KLRD1/CXCR6/CD27/CD40LG/MS4A1/CD86/CD83/CD6/CD19/BTN3A3/ICOS/EFNA5/CEACAM5/CD9/IL6ST/IGLC1/PECAM1/CD163/PRND/CD80/BTN3A1/GPC4/ICOSLG/HFE/TNFRSF4/ANPEP/IGHG1/CCR8/LIFR/GFRA2/GP1BA/S1PR1/TNFRSF9/IL2RA/ITGAV/CCRL2/STAB2/IL1R1/ITGAE/CDH5/LILRB1	100
CC	GO:0031983	vesicle lumen	76/2169	339/19717	9.169e-10	2.801e-07	2.346e-07	AMPD3/SERPINA1/S100A9/IGF1/PENK/BIN2/TIMP3/CLU/GCA/SERPINA3/FCN1/SLPI/COTL1/HBB/GNLY/CXCL1/MAGED2/CTSC/CFP/LYZ/TIMP2/PLAC8/FGR/CTSW/EGFR/HK3/CYB5R3/SRGN/ADA/PTPN6/PROS1/ALDOC/F5/HSPA6/GTPBP2/HGF/GMFG/CFD/FAM3C/APOOL/NFKB1/QPCT/RAB27A/DOCK2/VCP/SERPINI1/MNDA/FUCA1/PNP/FAM49B/HSP90AB1/PRDX6/FABP5/FRK/TGFB3/SERPINB1/C6orf120/BACE1/APAF1/HP/GLA/CDC37L1/VEGFB/MAN2B1/CAT/ALAD/CANT1/VTI1B/MVP/GSN/PTX3/ACTR2/ALOX5/NHLRC2/CTSH/ISLR	76
CC	GO:0005819	spindle	77/2169	347/19717	1.169e-09	2.801e-07	2.346e-07	EML4/TACC3/ASPM/MYH10/PPP2CA/NUSAP1/MAPRE2/MAP4/TTC28/VRK1/LRMP/EML1/MAD2L1/GOLGA2/PLK1/TPX2/BORA/GEM/CKAP2/CDC14B/KIF11/CDCA8/KIF15/KIF18B/CDC25B/KIF3B/TPR/CDK1/MAP9/DLGAP5/ZNF207/STAG2/BUB1B/KIF4A/NEK7/DYNC1I1/MAP7D3/PRC1/NEK2/PPP2CB/CSPP1/KIF20A/PLK2/RACGAP1/ECT2/CDC7/CCNB1/TERF1/PARP4/CBX1/FBXO5/IKBKG/BEX4/HSPB1/CTTN/CEP85/CENPF/TTK/SNCG/AURKB/RB1/CEP63/KLHL21/CDC20/SLC25A5/MTUS1/SHCBP1/TUBG2/PKD2/KIF20B/ARL3/AURKA/KIFC1/TOPBP1/TBL1X/SPIN1/KIF23	77
CC	GO:0060205	cytoplasmic vesicle lumen	75/2169	338/19717	1.92e-09	3.451e-07	2.89e-07	AMPD3/SERPINA1/S100A9/IGF1/PENK/BIN2/TIMP3/CLU/GCA/SERPINA3/FCN1/SLPI/COTL1/HBB/GNLY/CXCL1/MAGED2/CTSC/CFP/LYZ/TIMP2/PLAC8/FGR/CTSW/HK3/CYB5R3/SRGN/ADA/PTPN6/PROS1/ALDOC/F5/HSPA6/GTPBP2/HGF/GMFG/CFD/FAM3C/APOOL/NFKB1/QPCT/RAB27A/DOCK2/VCP/SERPINI1/MNDA/FUCA1/PNP/FAM49B/HSP90AB1/PRDX6/FABP5/FRK/TGFB3/SERPINB1/C6orf120/BACE1/APAF1/HP/GLA/CDC37L1/VEGFB/MAN2B1/CAT/ALAD/CANT1/VTI1B/MVP/GSN/PTX3/ACTR2/ALOX5/NHLRC2/CTSH/ISLR	75
CC	GO:0034774	secretory granule lumen	71/2169	321/19717	5.945e-09	8.548e-07	7.159e-07	AMPD3/SERPINA1/S100A9/IGF1/PENK/BIN2/TIMP3/CLU/GCA/SERPINA3/FCN1/SLPI/COTL1/CXCL1/MAGED2/CTSC/CFP/LYZ/TIMP2/PLAC8/FGR/CTSW/HK3/CYB5R3/SRGN/PTPN6/PROS1/ALDOC/F5/HSPA6/GTPBP2/HGF/GMFG/CFD/FAM3C/APOOL/NFKB1/QPCT/RAB27A/DOCK2/VCP/SERPINI1/MNDA/FUCA1/PNP/FAM49B/HSP90AB1/PRDX6/FABP5/FRK/TGFB3/SERPINB1/C6orf120/APAF1/HP/GLA/CDC37L1/VEGFB/MAN2B1/CAT/ALAD/CANT1/VTI1B/MVP/GSN/PTX3/ACTR2/ALOX5/NHLRC2/CTSH/ISLR	71
CC	GO:0030139	endocytic vesicle	65/2169	303/19717	8.746e-08	1.048e-05	8.777e-06	CTLA4/TAP1/TAPBP/CORO1A/WNT5B/HLA-F/HLA-A/RAC2/TAP2/HLA-C/RAB8A/LPAR1/TLR2/CD74/TBC1D5/TCIRG1/HBB/GNLY/HLA-G/ADAM8/WLS/DYSF/CD36/ITSN1/WASL/ANXA3/EGFR/HLA-E/HBEGF/SPHK1/HLA-DRA/HLA-DPB1/HLA-B/WAS/PLD1/SCARF1/FCGR1B/NCF4/FZD4/RAB20/CD9/COLEC12/KIF16B/HLA-DQB2/STXBP2/CD163/ENTPD7/MYO1C/STX4/SYK/STXBP1/SCARB2/HLA-DPA1/HP/CYBA/NCF1/STX6/FZD2/LMBRD1/ITGAV/STAB2/RAB14/GSN/TLR6/RAB11FIP1	65
CC	GO:0062023	collagen-containing extracellular matrix	79/2169	406/19717	2.986e-07	3.026e-05	2.534e-05	PRELP/ADAMDEC1/SERPINA1/SFRP1/S100A9/FMOD/SCARA3/GPC5/WNT5B/TIMP3/MXRA7/CLU/MGP/SERPINA3/FCN1/ADAM19/DPT/SERPINA5/OGN/CTSF/SLPI/LTBP3/CDON/MFAP4/HTRA1/KAZALD1/SULF1/ECM2/LAMA2/ICAM1/EFEMP2/LGALS9/CILP/COCH/LTBP2/CTSC/CFP/TIMP2/COMP/CTSL/FBLN5/COL8A2/DAG1/THBS4/DCN/BGN/SPON1/COL8A1/CSPG4/COL14A1/ITIH5/EDIL3/PTN/LUM/CDH2/EFEMP1/PCOLCE/VCAN/CTSB/EFNA5/COL15A1/MYOC/NAV2/CPA3/ADIPOQ/PODNL1/FGF9/GPC4/TGFB3/SERPINB1/ANXA4/PLSCR1/FBLN1/ANG/ANGPTL2/TGM2/CASK/COL16A1/CTSH	79
CC	GO:0001772	immunological synapse	16/2169	36/19717	3.68e-07	3.026e-05	2.534e-05	LCK/GZMA/CD3E/CORO1A/PRKCQ/LAT/GZMB/ICAM1/ZAP70/RHOH/CD53/SKAP1/CD6/SOCS6/CD37/CD81	16
CC	GO:0098857	membrane microdomain	65/2169	316/19717	4.376e-07	3.026e-05	2.534e-05	LCK/PTPRC/CD2/LRP6/CD48/BIRC3/CSK/TNFRSF1B/CD8A/ADD3/RFTN1/LAT/PPP2CA/ANK2/SGCA/TLR2/EMP2/ANGPT1/LCP2/ITGB2/SULF1/FXYD1/EFHD2/ICAM1/BMPR1A/DYSF/JAK2/CD36/EGFR/PDPN/DAG1/DLC1/NPC1/ZAP70/SELE/CD226/EPHB1/CDH2/SKAP1/MS4A1/HTR2A/CD19/ATP1B1/EFNA5/PECAM1/ATP1A2/MYO1C/ERLIN2/EDNRB/SORBS1/BACE1/BTK/INPP5D/SELPLG/PLSCR1/TFPI/SLC25A5/CLIP3/LYN/KDR/HCK/CFLAR/S1PR1/STOML1/TLR6	65
CC	GO:0042611	MHC protein complex	13/2169	25/19717	4.83e-07	3.026e-05	2.534e-05	HLA-F/HLA-A/HLA-C/CD74/HLA-G/HLA-E/HLA-DRA/HLA-DPB1/HLA-B/HLA-DMA/HLA-DMB/HLA-DQB2/HLA-DPA1	13
CC	GO:0045335	phagocytic vesicle	35/2169	132/19717	5.211e-07	3.026e-05	2.534e-05	TAP1/TAPBP/CORO1A/HLA-F/HLA-A/RAC2/TAP2/HLA-C/RAB8A/TLR2/TCIRG1/GNLY/HLA-G/ADAM8/CD36/ANXA3/HLA-E/HLA-B/WAS/NCF4/RAB20/KIF16B/STXBP2/MYO1C/STX4/SYK/STXBP1/CYBA/NCF1/STX6/ITGAV/RAB14/GSN/TLR6/RAB11FIP1	35
CC	GO:0005925	focal adhesion	78/2169	405/19717	5.432e-07	3.026e-05	2.534e-05	LCP1/CPNE3/PTPRC/LAP3/EPB41L2/DDR2/LPXN/ITGB7/RAC2/ITGA4/MPZL1/MAPRE2/GAK/ITGB2/FERMT2/ICAM1/JAK2/RPL31/IRF2/EGFR/LPP/TNS1/DAG1/ITGBL1/DLC1/STARD8/PROCR/FHL1/MRC2/CSPG4/AKAP12/ARHGAP22/ENAH/SORBS2/STX16/NOX4/CDH2/PARVA/REXO2/RRAS/ZFYVE21/VASP/DIXDC1/ARPC5L/CORO2B/CD9/RHOG/RPS4X/PDLIM1/TNS3/MTF2/PAK1/RPL12/TRIP6/SORBS1/HSPB1/CTTN/SCARB2/CFL1/FERMT1/CYBA/ADAM10/HMGA1/HCK/CD81/CAT/TGM2/ACTR3/FZD2/RPL10A/PFN1/ITGAV/CASK/LIMS2/GSN/RPS14/ACTR2/KIF23	78
CC	GO:0030666	endocytic vesicle membrane	41/2169	167/19717	5.47e-07	3.026e-05	2.534e-05	TAP1/TAPBP/CORO1A/WNT5B/HLA-F/HLA-A/RAC2/TAP2/HLA-C/RAB8A/TLR2/CD74/TBC1D5/TCIRG1/HLA-G/WLS/CD36/WASL/ANXA3/HLA-E/HBEGF/HLA-DRA/HLA-DPB1/HLA-B/SCARF1/FCGR1B/FZD4/RAB20/CD9/COLEC12/HLA-DQB2/CD163/ENTPD7/STX4/SCARB2/HLA-DPA1/CYBA/FZD2/STAB2/TLR6/RAB11FIP1	41
CC	GO:0005924	cell-substrate adherens junction	78/2169	408/19717	7.358e-07	3.779e-05	3.164e-05	LCP1/CPNE3/PTPRC/LAP3/EPB41L2/DDR2/LPXN/ITGB7/RAC2/ITGA4/MPZL1/MAPRE2/GAK/ITGB2/FERMT2/ICAM1/JAK2/RPL31/IRF2/EGFR/LPP/TNS1/DAG1/ITGBL1/DLC1/STARD8/PROCR/FHL1/MRC2/CSPG4/AKAP12/ARHGAP22/ENAH/SORBS2/STX16/NOX4/CDH2/PARVA/REXO2/RRAS/ZFYVE21/VASP/DIXDC1/ARPC5L/CORO2B/CD9/RHOG/RPS4X/PDLIM1/TNS3/MTF2/PAK1/RPL12/TRIP6/SORBS1/HSPB1/CTTN/SCARB2/CFL1/FERMT1/CYBA/ADAM10/HMGA1/HCK/CD81/CAT/TGM2/ACTR3/FZD2/RPL10A/PFN1/ITGAV/CASK/LIMS2/GSN/RPS14/ACTR2/KIF23	78
CC	GO:0045121	membrane raft	64/2169	315/19717	8.403e-07	4.028e-05	3.373e-05	LCK/PTPRC/CD2/LRP6/CD48/BIRC3/CSK/TNFRSF1B/CD8A/ADD3/RFTN1/LAT/PPP2CA/ANK2/SGCA/TLR2/EMP2/ANGPT1/LCP2/ITGB2/SULF1/FXYD1/EFHD2/ICAM1/BMPR1A/JAK2/CD36/EGFR/PDPN/DAG1/DLC1/NPC1/ZAP70/SELE/CD226/EPHB1/CDH2/SKAP1/MS4A1/HTR2A/CD19/ATP1B1/EFNA5/PECAM1/ATP1A2/MYO1C/ERLIN2/EDNRB/SORBS1/BACE1/BTK/INPP5D/SELPLG/PLSCR1/TFPI/SLC25A5/CLIP3/LYN/KDR/HCK/CFLAR/S1PR1/STOML1/TLR6	64
CC	GO:0030055	cell-substrate junction	78/2169	412/19717	1.094e-06	4.915e-05	4.116e-05	LCP1/CPNE3/PTPRC/LAP3/EPB41L2/DDR2/LPXN/ITGB7/RAC2/ITGA4/MPZL1/MAPRE2/GAK/ITGB2/FERMT2/ICAM1/JAK2/RPL31/IRF2/EGFR/LPP/TNS1/DAG1/ITGBL1/DLC1/STARD8/PROCR/FHL1/MRC2/CSPG4/AKAP12/ARHGAP22/ENAH/SORBS2/STX16/NOX4/CDH2/PARVA/REXO2/RRAS/ZFYVE21/VASP/DIXDC1/ARPC5L/CORO2B/CD9/RHOG/RPS4X/PDLIM1/TNS3/MTF2/PAK1/RPL12/TRIP6/SORBS1/HSPB1/CTTN/SCARB2/CFL1/FERMT1/CYBA/ADAM10/HMGA1/HCK/CD81/CAT/TGM2/ACTR3/FZD2/RPL10A/PFN1/ITGAV/CASK/LIMS2/GSN/RPS14/ACTR2/KIF23	78
CC	GO:0072686	mitotic spindle	30/2169	109/19717	1.423e-06	6.018e-05	5.04e-05	EML4/TACC3/ASPM/NUSAP1/MAP4/TTC28/EML1/MAD2L1/GOLGA2/TPX2/GEM/CDC14B/KIF11/KIF18B/TPR/CDK1/MAP9/STAG2/RACGAP1/ECT2/CDC7/IKBKG/CTTN/AURKB/PKD2/KIF20B/AURKA/KIFC1/TBL1X/KIF23	30
CC	GO:0098589	membrane region	65/2169	328/19717	1.711e-06	6.836e-05	5.725e-05	LCK/PTPRC/CD2/LRP6/CD48/BIRC3/CSK/TNFRSF1B/CD8A/ADD3/RFTN1/LAT/PPP2CA/ANK2/SGCA/TLR2/EMP2/ANGPT1/LCP2/ITGB2/SULF1/FXYD1/EFHD2/ICAM1/BMPR1A/DYSF/JAK2/CD36/EGFR/PDPN/DAG1/DLC1/NPC1/ZAP70/SELE/CD226/EPHB1/CDH2/SKAP1/MS4A1/HTR2A/CD19/ATP1B1/EFNA5/PECAM1/ATP1A2/MYO1C/ERLIN2/EDNRB/SORBS1/BACE1/BTK/INPP5D/SELPLG/PLSCR1/TFPI/SLC25A5/CLIP3/LYN/KDR/HCK/CFLAR/S1PR1/STOML1/TLR6	65
CC	GO:0031091	platelet alpha granule	26/2169	91/19717	3.295e-06	0.0001247	0.0001044	SERPINA1/IGF1/CLU/SERPINA3/SERPINA5/MAGED2/CD36/SRGN/PROS1/F5/PHACTR2/GTPBP2/HGF/CFD/APOOL/CYB5R1/CD9/PECAM1/FAM49B/STXBP1/TGFB3/APLP2/VEGFB/VTI1B/NHLRC2/ISLR	26
CC	GO:0071556	integral component of lumenal side of endoplasmic reticulum membrane	13/2169	29/19717	4.121e-06	0.0001411	0.0001182	TAPBP/HLA-F/HLA-A/HLA-C/CD74/HLA-G/HLA-E/HLA-DRA/HLA-DPB1/HLA-B/HLA-DQB2/HLA-DPA1/PKD2	13
CC	GO:0098553	lumenal side of endoplasmic reticulum membrane	13/2169	29/19717	4.121e-06	0.0001411	0.0001182	TAPBP/HLA-F/HLA-A/HLA-C/CD74/HLA-G/HLA-E/HLA-DRA/HLA-DPB1/HLA-B/HLA-DQB2/HLA-DPA1/PKD2	13
CC	GO:0030027	lamellipodium	43/2169	193/19717	4.624e-06	0.0001511	0.0001265	KITLG/WASF3/CORO1A/RAC2/MYH10/PDLIM4/ARPIN/ANTXR1/ITGB1BP1/FERMT2/DYSF/ITSN1/WASL/PDPN/DAG1/CDC42BPA/CSPG4/ENAH/SORBS2/CDH2/PARVA/UNC5C/VASP/PTPN13/ABLIM1/PIK3CA/PAK1/STX4/DPYSL3/CTTN/SLC39A6/FER/CFL1/TESC/PKD2/MYLK/WASF2/ABI2/ACTR3/ITGAV/IQGAP2/GSN/ACTR2	43
CC	GO:0030667	secretory granule membrane	59/2169	298/19717	5.214e-06	0.000163	0.0001365	LAMP3/CPNE3/PTPRC/STK10/TMC6/TNFRSF1B/LILRB2/SERPINA5/SRI/TLR2/TCIRG1/ABCC4/ITGB2/LILRA3/PAM/LRMP/SELL/ADAM8/LILRB3/CD36/RHOF/PGRMC1/ATP8A1/ITGAL/PHACTR2/CR1/MAGT1/CD93/PLD1/NCKAP1L/CD53/CYB5R1/SLC2A3/CPE/RAB27A/CD9/FPR1/RHOG/PECAM1/STXBP2/PLA1A/FABP5/ITGAX/VAMP2/TSPAN14/ANPEP/CD38/FPR2/APLP2/CYBA/ADAM10/ABCA3/MANBA/NBEAL2/ITGAV/SLC2A5/FCGR3B/IQGAP2/RAB14	59
CC	GO:0042581	specific granule	37/2169	160/19717	8.536e-06	0.0002513	0.0002104	STK10/TMC6/TNFRSF1B/SLPI/ITGB2/LILRA3/ADAM8/CXCL1/CD36/CFP/LYZ/TIMP2/ANXA3/PGRMC1/ATP8A1/PTPN6/ITGAL/CD93/PLD1/CD53/NFKB1/SLC2A3/QPCT/RAB27A/DOCK2/STXBP2/STX4/FRK/TSPAN14/HP/FPR2/CYBA/ADAM10/CANT1/ITGAV/SLC2A5/PTX3	37
CC	GO:0101002	ficolin-1-rich granule	41/2169	185/19717	8.737e-06	0.0002513	0.0002104	AMPD3/SERPINA1/BIN2/LILRB2/FCN1/COTL1/TCIRG1/HBB/ITGB2/LILRA3/ADAM8/TIMP2/HK3/ALDOC/HSPA6/CR1/PLEKHO2/CD93/NCKAP1L/GMFG/CFD/SLC2A3/CTSB/QPCT/VCP/FPR1/MNDA/PNP/HSP90AB1/ITGAX/APAF1/FPR2/CAT/ALAD/CANT1/NBEAL2/MVP/GSN/ACTR2/ALOX5/CTSH	41
CC	GO:0000307	cyclin-dependent protein kinase holoenzyme complex	15/2169	42/19717	2.17e-05	0.0006002	0.0005026	CCND2/CCNB2/CCNT1/CDK1/CCNA2/CDK14/CKS2/CCNI/CCNB1/CCND1/CKS1B/RB1/CCNG1/CCNF/CCNE2	15
CC	GO:0030864	cortical actin cytoskeleton	24/2169	90/19717	2.766e-05	0.0007366	0.0006168	EPB41L2/CORO1A/COTL1/HCLS1/WASL/DLC1/CALD1/WAS/LANCL2/GMFG/CDH2/CAP2/DSTN/HFE/KRT19/CTTN/AKAP13/CFL1/CAPZA1/WDR1/ACTR3/SPTBN1/GSN/ACTR2	24
CC	GO:0005884	actin filament	27/2169	111/19717	5.328e-05	0.001368	0.001146	LCP1/CORO1A/GNG12/RAC2/PDLIM4/TMOD1/SH2B2/COTL1/HCLS1/COBL/WASL/PSTPIP2/WAS/GAS7/PDLIM5/PLS3/LMOD1/PDLIM1/PAK1/MYO1C/DPYSL3/CTTN/AKAP13/PKD2/HCK/MYO3A/WDR1	27
CC	GO:0031252	cell leading edge	70/2169	403/19717	7.228e-05	0.001764	0.001477	LCP1/KITLG/PLEKHA1/WASF3/CORO1A/PLEKHO1/GABARAPL1/RAC2/MYH10/PDLIM4/CXCR4/ARPIN/SH2B2/ANTXR1/ITGB1BP1/FERMT2/WLS/DYSF/SAMSN1/ARHGEF26/ITSN1/COBL/WASL/FGR/PDPN/DAG1/DLC1/CDC42BPA/SH3YL1/CSPG4/PLEK/ENAH/SGCE/MTMR14/SORBS2/CDH2/PARVA/UNC5C/SKAP1/DDX58/SNX5/PSD3/VASP/PTPN13/ABLIM1/KANK1/PIK3CA/PAK1/MYO1C/STX4/PSD4/DPYSL3/CTTN/SLC39A6/FER/IFIT5/CFL1/TESC/FERMT1/PKD2/MYLK/WASF2/ABI2/ACTR3/ITGAV/ATP6V1B2/IQGAP2/SPTBN1/GSN/ACTR2	70
CC	GO:0030176	integral component of endoplasmic reticulum membrane	33/2169	150/19717	7.36e-05	0.001764	0.001477	PIGK/TAP1/TAPBP/HLA-F/HLA-A/TAP2/HLA-C/CD74/SEC62/SGPL1/HLA-G/HLA-E/DPM3/HLA-DRA/HLA-DPB1/HLA-B/GPAA1/SLC37A1/EDEM1/EMC2/HLA-DQB2/SGMS1/HLA-DPA1/ELOVL4/DHRS9/EMC8/SLC27A5/EMC6/PKD2/PIGT/ELOVL2/ERGIC2/ELOVL5	33
CC	GO:0000922	spindle pole	35/2169	164/19717	8.706e-05	0.001956	0.001638	TACC3/ASPM/PPP2CA/TTC28/LRMP/EML1/MAD2L1/GOLGA2/PLK1/TPX2/CKAP2/CDC14B/KIF11/CDC25B/DLGAP5/STAG2/NEK7/DYNC1I1/PRC1/NEK2/PPP2CB/CSPP1/PLK2/CCNB1/IKBKG/BEX4/CEP85/CENPF/AURKB/CEP63/KLHL21/CDC20/KIF20B/AURKA/TOPBP1	35
CC	GO:0070820	tertiary granule	35/2169	164/19717	8.706e-05	0.001956	0.001638	TMC6/METTL7A/LILRB2/TCIRG1/HBB/ITGB2/LILRA3/ADAM8/CXCL1/CFP/LYZ/TIMP2/PTPN6/ALDOC/CR1/CD93/PLD1/NCKAP1L/CD53/SLC2A3/QPCT/FPR1/STXBP2/ITGAX/TSPAN14/HP/FPR2/CYBA/ADAM10/GOLGA7/CANT1/NBEAL2/RAB14/PTX3/CTSH	35
CC	GO:0005775	vacuolar lumen	36/2169	172/19717	0.0001058	0.002305	0.00193	PRELP/FMOD/GPC5/GCA/SERPINA3/OGN/CTSF/CD74/CTSC/LYZ/PLAC8/CTSL/CYB5R3/DCN/BGN/CSPG4/ACP2/LUM/VCAN/CTSB/HYAL1/IDUA/VCP/MNDA/FUCA1/PRDX6/FABP5/GPC4/FRK/C6orf120/SCARB2/GLA/MAN2B1/NAAA/MANBA/ACTR2	36
CC	GO:0030863	cortical cytoskeleton	27/2169	116/19717	0.0001193	0.002523	0.002113	EPB41L2/CORO1A/TMOD1/COTL1/HCLS1/WASL/GYPC/DLC1/CALD1/SELE/WAS/LANCL2/GMFG/CDH2/CAP2/DSTN/HFE/KRT19/CTTN/AKAP13/CFL1/CAPZA1/WDR1/ACTR3/SPTBN1/GSN/ACTR2	27
CC	GO:0030135	coated vesicle	53/2169	289/19717	0.0001295	0.00266	0.002227	CD3D/COPZ2/SERPINA1/AP1G2/CTLA4/BTC/HLA-F/HLA-A/DENND1C/IL7R/HLA-C/RAB8A/CD74/TBC1D5/CD3G/HLA-G/NECAP2/CTSC/GOLGA2/SLC18A2/TFRC/EGFR/HLA-E/HBEGF/YIPF6/F5/HLA-DRA/HLA-DPB1/DENND1A/HLA-B/SEC31A/FCGR1B/VPS16/FZD4/YIPF5/RAB27A/KDELR3/CD9/IDUA/HLA-DQB2/VAMP2/KDELR2/SCARB2/HLA-DPA1/DVL1/ERGIC2/STX6/VTI1B/FZD2/LMBRD1/CNIH1/SEC23B/RAB14	53
CC	GO:0030670	phagocytic vesicle membrane	20/2169	76/19717	0.000153	0.00302	0.002529	TAP1/TAPBP/CORO1A/HLA-F/HLA-A/RAC2/TAP2/HLA-C/RAB8A/TLR2/TCIRG1/HLA-G/ANXA3/HLA-E/HLA-B/RAB20/STX4/CYBA/TLR6/RAB11FIP1	20
CC	GO:1904813	ficolin-1-rich granule lumen	28/2169	124/19717	0.000157	0.00302	0.002529	AMPD3/SERPINA1/BIN2/FCN1/COTL1/HBB/TIMP2/HK3/ALDOC/HSPA6/PLEKHO2/GMFG/CFD/CTSB/QPCT/VCP/MNDA/PNP/HSP90AB1/APAF1/CAT/ALAD/CANT1/MVP/GSN/ACTR2/ALOX5/CTSH	28
CC	GO:0051233	spindle midzone	12/2169	34/19717	0.0001638	0.00302	0.002529	MAPRE2/EML1/PLK1/GEM/CDCA8/KIF18B/MAP9/RACGAP1/CTTN/AURKB/KIF20B/AURKA	12
CC	GO:0098636	protein complex involved in cell adhesion	12/2169	34/19717	0.0001638	0.00302	0.002529	CTLA4/ITGB7/ITGA4/ITGB2/ITGBL1/ITGAL/ITGA10/CD80/ITGAX/LYN/ITGAV/ITGAE	12
CC	GO:0043202	lysosomal lumen	23/2169	95/19717	0.0001995	0.003586	0.003003	PRELP/FMOD/GPC5/OGN/CTSF/CD74/CTSL/DCN/BGN/CSPG4/ACP2/LUM/VCAN/CTSB/HYAL1/IDUA/FUCA1/GPC4/SCARB2/GLA/MAN2B1/NAAA/MANBA	23
CC	GO:0031227	intrinsic component of endoplasmic reticulum membrane	33/2169	158/19717	0.0002094	0.003671	0.003074	PIGK/TAP1/TAPBP/HLA-F/HLA-A/TAP2/HLA-C/CD74/SEC62/SGPL1/HLA-G/HLA-E/DPM3/HLA-DRA/HLA-DPB1/HLA-B/GPAA1/SLC37A1/EDEM1/EMC2/HLA-DQB2/SGMS1/HLA-DPA1/ELOVL4/DHRS9/EMC8/SLC27A5/EMC6/PKD2/PIGT/ELOVL2/ERGIC2/ELOVL5	33
CC	GO:0031093	platelet alpha granule lumen	18/2169	67/19717	0.000243	0.004161	0.003484	SERPINA1/IGF1/CLU/SERPINA3/MAGED2/SRGN/PROS1/F5/GTPBP2/HGF/CFD/APOOL/FAM49B/TGFB3/VEGFB/VTI1B/NHLRC2/ISLR	18
CC	GO:0000780	condensed nuclear chromosome, centromeric region	10/2169	26/19717	0.0002558	0.004277	0.003581	BUB1/NDC80/PLK1/BUB1B/CENPB/ATRX/CCNB1/REC8/AURKB/AURKA	10
CC	GO:0030662	coated vesicle membrane	36/2169	182/19717	0.0003405	0.005471	0.004581	CD3D/COPZ2/AP1G2/BTC/HLA-F/HLA-A/IL7R/HLA-C/CD74/TBC1D5/CD3G/HLA-G/NECAP2/SLC18A2/TFRC/EGFR/HLA-E/HBEGF/HLA-DRA/HLA-DPB1/DENND1A/HLA-B/SEC31A/FCGR1B/FZD4/KDELR3/CD9/HLA-DQB2/VAMP2/KDELR2/SCARB2/HLA-DPA1/VTI1B/FZD2/CNIH1/SEC23B	36
CC	GO:0042383	sarcolemma	29/2169	136/19717	0.0003424	0.005471	0.004581	SSPN/SGCB/SYNM/SRI/CACNA2D1/ANK2/PPP3CA/SGCA/FXYD1/LAMA2/DYSF/KCNJ5/DAG1/BGN/SGCE/CDH2/SGCD/KCNJ2/ATP1B1/SCN1B/AHNAK2/ATP1A2/SLC8A1/POPDC2/TGFB3/KRT19/RYR3/SNTA1/SLC2A5	29
CC	GO:0030134	COPII-coated ER to Golgi transport vesicle	22/2169	93/19717	0.0003856	0.006026	0.005047	SERPINA1/HLA-F/HLA-A/HLA-C/CD74/HLA-G/CTSC/GOLGA2/HLA-E/YIPF6/F5/HLA-DRA/HLA-DPB1/HLA-B/SEC31A/YIPF5/HLA-DQB2/HLA-DPA1/ERGIC2/VTI1B/CNIH1/SEC23B	22
CC	GO:1902554	serine/threonine protein kinase complex	21/2169	88/19717	0.000457	0.006991	0.005854	CCND2/CCNB2/TBC1D5/CCNT1/PHKB/CDK1/CCNA2/CDK14/CKS2/CCNI/CCNB1/CCND1/ACVR1/IKBKG/CKS1B/IFIT5/RB1/CCNG1/CCNF/CCNE2/GTF2H5	21
CC	GO:0005911	cell-cell junction	74/2169	459/19717	0.0004828	0.007232	0.006056	ITK/PCDH9/PIK3R1/CD3E/CD2/CORO1A/CSK/DLG5/ADD3/PDLIM4/CDH19/CYTH1/LAT/PARD3/ANK2/PPP3CA/SGCA/JAM3/LCP2/TMEM47/RASIP1/FXYD1/MXRA8/AKR1B1/CDCA3/AMOTL2/DAG1/PTPN6/PMP22/CDC42BPA/ZAP70/FGF13/ARHGAP17/WAS/MAGI2/PDLIM5/CDH2/CADM1/CD53/KCNJ2/SKAP1/DDX58/FZD4/ATP1B1/VASP/VAV1/SCN1B/ECT2/DSC2/PPP1CA/PDLIM1/PECAM1/ATP1A2/SLC8A1/PNN/PAK1/CCND1/SORBS1/CFL1/DDX6/LYN/PANX1/MPP5/PKD2/GJC1/WASF2/WDR1/ACTR3/CASK/LIMS2/CLDN14/NPHP4/CDH5/AHI1	74
CC	GO:0016010	dystrophin-associated glycoprotein complex	8/2169	19/19717	0.0005229	0.007379	0.006179	SSPN/SGCB/SGCA/DAG1/SGCE/SGCD/KRT19/SNTA1	8
CC	GO:0090665	glycoprotein complex	8/2169	19/19717	0.0005229	0.007379	0.006179	SSPN/SGCB/SGCA/DAG1/SGCE/SGCD/KRT19/SNTA1	8
CC	GO:0098687	chromosomal region	59/2169	349/19717	0.0005259	0.007379	0.006179	PURA/PPP2CA/BUB1/SIRT7/NCAPD2/NDC80/MAD2L1/SMC6/DYNC1LI2/PLK1/CDCA8/BLM/HJURP/NCAPG/TPR/CDK1/ZNF207/EZH2/STAG2/BUB1B/MCM5/KIF2C/NUP160/DYNC1I1/CENPB/NEK2/PPP2CB/FEN1/DNMT1/ATRX/SPC25/ZWINT/STAG3/LRIF1/MCM2/CCNB1/PPP1CA/THOC2/TERF1/CBX1/PARP1/DCTN6/CENPF/REC8/TTK/HELLS/SCMH1/AURKB/MCM4/ERCC6L/IKZF1/ERCC1/THOC1/CENPM/EZH1/SMCHD1/AURKA/THOC6/PML	59
CC	GO:0000775	chromosome, centromeric region	37/2169	193/19717	0.0005337	0.007379	0.006179	PPP2CA/BUB1/NCAPD2/NDC80/MAD2L1/DYNC1LI2/PLK1/CDCA8/HJURP/NCAPG/TPR/ZNF207/STAG2/BUB1B/KIF2C/NUP160/DYNC1I1/CENPB/NEK2/PPP2CB/DNMT1/ATRX/SPC25/ZWINT/STAG3/CCNB1/CBX1/DCTN6/CENPF/REC8/TTK/HELLS/AURKB/ERCC6L/IKZF1/CENPM/AURKA	37
CC	GO:0005874	microtubule	68/2169	416/19717	0.0005462	0.007409	0.006205	EML4/DYNC2LI1/GABARAPL1/ASPM/TPPP3/NUSAP1/MAPRE2/MAP4/MAP3K11/EML1/DYSF/GOLGA2/DYNC1LI2/PLK1/TPX2/TUBA4A/DNM1/TUBB2B/CKAP2/KIF11/KIF15/KIF18B/KIF3B/FGF13/KIF21B/CDK1/MAP9/BAG2/ZNF207/TTLL1/TUBB4A/HOOK2/KIF2C/KIF4A/NEK7/DYNC1I1/PRC1/NEK2/SKAP1/CSPP1/KIF20A/RACGAP1/FEZ1/KIF16B/SLC8A1/PARP4/CAMSAP2/BEX4/MAP1B/ARHGAP4/SYBU/DPYSL2/AURKB/KLHL21/MTUS1/TUBG2/PBXIP1/DVL1/KIF20B/DYNLRB1/ARL3/SS18/AURKA/KIFC1/KIF1B/TPGS2/LRRC49/KIF23	68
CC	GO:0010008	endosome membrane	76/2169	479/19717	0.0006579	0.008638	0.007233	LAMP3/AP1G2/LRP6/TLR8/MICALL1/HLA-F/MREG/HLA-A/PDLIM4/MYD88/NTRK2/HLA-C/RAB8A/ANTXR1/TBC1D5/TCIRG1/HLA-G/ACAP1/IRF7/CLCN4/WLS/CDIP1/MMD/TFRC/EGFR/HLA-E/ATP9A/SPHK1/NPC1/HLA-DRA/HLA-DPB1/HLA-B/ERBB2/PLD1/FCGR1B/EHD4/EPHB1/NCF4/HLA-DMA/PMEPA1/VPS16/SNX5/TOM1L1/HLA-DMB/RAB27A/VPS37C/FZD7/LDLRAD4/KIF16B/YIPF1/OR51E2/HLA-DQB2/PRAF2/BACE1/RHOD/SCARB2/HLA-DPA1/CD320/CHMP2B/ABHD6/CLIP3/NDFIP1/OSBPL9/SNX10/DIO3/CD164/MTMR2/VTI1B/RAB11FIP2/CLCN5/STOML1/PARM1/SH3GL3/RAB14/CHMP1B/PML	76
CC	GO:1902911	protein kinase complex	24/2169	109/19717	0.0006607	0.008638	0.007233	CCND2/CCNB2/TBC1D5/CCNT1/PHKB/CDK1/SIK1/CCNA2/CDK14/CKS2/CCNI/CCNB1/CCND1/ACVR1/SORBS1/IKBKG/CKS1B/IFIT5/RB1/CCNG1/CCNF/PRKAB1/CCNE2/GTF2H5	24
CC	GO:0042641	actomyosin	19/2169	79/19717	0.000755	0.009694	0.008118	LCP1/LIMCH1/MYH10/PDLIM4/SH2B2/FERMT2/HDAC4/LPP/CDC42BPA/PDLIM5/NOX4/ABLIM1/PDLIM1/TRIP6/SORBS1/MYL9/CYBA/MYLK/WDR1	19
CC	GO:0042613	MHC class II protein complex	7/2169	16/19717	0.0008976	0.01119	0.009372	CD74/HLA-DRA/HLA-DPB1/HLA-DMA/HLA-DMB/HLA-DQB2/HLA-DPA1	7
CC	GO:0071564	npBAF complex	6/2169	12/19717	0.0009028	0.01119	0.009372	SMARCD3/SMARCC2/SMARCA2/SMARCD1/PHF10/SS18	6
CC	GO:0032432	actin filament bundle	18/2169	75/19717	0.001055	0.01286	0.01077	LCP1/LIMCH1/MYH10/PDLIM4/SH2B2/FERMT2/CRYAB/LPP/PDLIM5/NOX4/PLS3/ABLIM1/PDLIM1/TRIP6/SORBS1/MYL9/CYBA/MYLK	18
CC	GO:0030496	midbody	33/2169	173/19717	0.001131	0.01355	0.01135	LAP3/ASPM/MYH10/RAB8A/TTC28/PLK1/GEM/CDCA8/USP3/CEP55/KIF3B/TACC1/CDK1/KIF4A/PRC1/NEK2/KIF20A/URB2/RACGAP1/ECT2/GDI1/MICAL1/CNTRL/KLHL9/CENPF/AURKB/SHCBP1/KIF20B/ARL3/LYRM1/AURKA/CHMP1B/KIF23	33
CC	GO:0008305	integrin complex	10/2169	31/19717	0.001277	0.01505	0.0126	ITGB7/ITGA4/ITGB2/ITGBL1/ITGAL/ITGA10/ITGAX/LYN/ITGAV/ITGAE	10
CC	GO:0005876	spindle microtubule	15/2169	59/19717	0.001445	0.01676	0.01404	NUSAP1/PLK1/KIF11/KIF18B/KIF3B/CDK1/MAP9/KIF4A/PRC1/PARP4/AURKB/KLHL21/TUBG2/ARL3/AURKA	15
CC	GO:1990023	mitotic spindle midzone	6/2169	13/19717	0.001521	0.01736	0.01454	EML1/KIF18B/MAP9/CTTN/AURKB/KIF20B	6
CC	GO:0005769	early endosome	57/2169	350/19717	0.001599	0.01782	0.01492	LAMP3/EPHA3/CYTIP/LRP6/CORO1A/HLA-F/HLA-A/PDLIM4/RFTN1/CXCR4/TBC1D16/NTRK2/HLA-C/ANK2/HLA-G/ACKR3/CLCN4/WLS/DYSF/TRAK2/TFRC/EGFR/HLA-E/ATP9A/SPHK1/HLA-B/FCGR1B/EHD4/EPHB1/TMEM230/PMEPA1/VPS16/SNX5/RABGAP1L/RAB20/LDLRAD4/LIPG/KIF16B/OR51E2/HFE/BACE1/RHOD/AP1AR/CLIP3/KDR/AOC3/WASF2/STX6/MTMR2/VTI1B/CLCN5/USP10/PARM1/SH3GL3/RAB14/KIFC1/PML	57
CC	GO:0031258	lamellipodium membrane	8/2169	22/19717	0.001636	0.01782	0.01492	ANTXR1/FERMT2/PDPN/CSPG4/VASP/SLC39A6/CFL1/ITGAV	8
CC	GO:0042629	mast cell granule	8/2169	22/19717	0.001636	0.01782	0.01492	RASGRP1/LAT/AKR1B1/SRGN/S100A13/PIK3CD/BTK/LYN	8
CC	GO:0035579	specific granule membrane	20/2169	91/19717	0.001832	0.01966	0.01647	STK10/TMC6/TNFRSF1B/ITGB2/LILRA3/ADAM8/CD36/PGRMC1/ATP8A1/ITGAL/CD93/PLD1/CD53/SLC2A3/TSPAN14/FPR2/CYBA/ADAM10/ITGAV/SLC2A5	20
CC	GO:0005938	cell cortex	51/2169	308/19717	0.00191	0.0202	0.01691	CYTIP/EPB41L2/CORO1A/BIN2/ADD3/MYH10/TMOD1/PARD3/COTL1/RHOBTB3/HCLS1/FERMT2/RHOF/COBL/WASL/GYPC/MELK/DLC1/CALD1/FNBP1/SELE/WAS/AKAP12/RHOH/ASPH/LANCL2/GMFG/CDH2/CAP2/PLA2G4C/DSTN/RHOG/FNBP1L/RAI14/CLIC5/HFE/KRT19/CTTN/RHOD/AKAP13/FER/CFL1/CAPZA1/PKD2/WDR1/SPINK5/ACTR3/PFN1/SPTBN1/GSN/ACTR2	51
CC	GO:1904724	tertiary granule lumen	14/2169	55/19717	0.002031	0.02096	0.01755	METTL7A/HBB/CXCL1/CFP/LYZ/TIMP2/PTPN6/ALDOC/QPCT/HP/GOLGA7/CANT1/PTX3/CTSH	14
CC	GO:0001725	stress fiber	16/2169	67/19717	0.00207	0.02096	0.01755	LCP1/LIMCH1/MYH10/PDLIM4/SH2B2/FERMT2/LPP/PDLIM5/NOX4/ABLIM1/PDLIM1/TRIP6/SORBS1/MYL9/CYBA/MYLK	16
CC	GO:0097517	contractile actin filament bundle	16/2169	67/19717	0.00207	0.02096	0.01755	LCP1/LIMCH1/MYH10/PDLIM4/SH2B2/FERMT2/LPP/PDLIM5/NOX4/ABLIM1/PDLIM1/TRIP6/SORBS1/MYL9/CYBA/MYLK	16
CC	GO:0000779	condensed chromosome, centromeric region	24/2169	118/19717	0.002102	0.02099	0.01758	BUB1/NCAPD2/NDC80/MAD2L1/PLK1/HJURP/NCAPG/ZNF207/BUB1B/KIF2C/DYNC1I1/CENPB/NEK2/ATRX/SPC25/ZWINT/CCNB1/DCTN6/CENPF/REC8/AURKB/ERCC6L/CENPM/AURKA	24
CC	GO:0061695	transferase complex, transferring phosphorus-containing groups	44/2169	259/19717	0.002282	0.02248	0.01882	PIK3R1/CCND2/CCNB2/TBC1D5/SOCS1/CISH/TAF7/RPAP2/CCNT1/PHKB/CDK1/SIK1/CCNA2/SOCS2/PIK3CD/REV3L/CDK14/CKS2/GTF2F1/CCNI/CCNB1/SOCS6/PIK3CA/CCND1/POLR2L/ACVR1/SORBS1/IKBKG/GTF2A1/CKS1B/PAF1/PIK3R3/IFIT5/POLE2/RPRD1A/RB1/CCNG1/ERCC1/CCNF/TP53/PRKAB1/CCNE2/PRPS2/GTF2H5	44
CC	GO:0000940	condensed chromosome outer kinetochore	6/2169	14/19717	0.002415	0.02347	0.01965	BUB1/NDC80/PLK1/BUB1B/CCNB1/CENPF	6
CC	GO:0012507	ER to Golgi transport vesicle membrane	15/2169	62/19717	0.002458	0.02356	0.01973	HLA-F/HLA-A/HLA-C/CD74/HLA-G/HLA-E/HLA-DRA/HLA-DPB1/HLA-B/SEC31A/HLA-DQB2/HLA-DPA1/VTI1B/CNIH1/SEC23B	15
CC	GO:0043025	neuronal cell body	75/2169	497/19717	0.002832	0.02679	0.02243	CCR2/UCHL1/LRP6/PENK/NQO1/TNFRSF1B/MYH10/NDN/PURA/ITGA4/RAB8A/PARD3/LPAR1/KCNK1/CD200/PAM/BMPR1A/CRYAB/TRAK2/TPX2/ITSN1/TIMP2/COBL/ANXA3/PGRMC1/SNCAIP/ADA/PDE1A/SLC1A3/PDYN/TAC1/DENND1A/TMEM100/AKAP12/KCNK2/TBX21/CX3CR1/TUBB4A/PTPRF/SOD1/UNC5C/KCNJ2/ZPR1/VPS16/PTPRS/SLC2A3/HTR2A/CPE/SCN1B/FEZ1/GDI1/IL6ST/SERPINI1/PPP1CA/HSP90AB1/TGFB3/BACE1/MAP1B/SNCG/SEMA4F/RIC3/CYBA/ADAM10/ANG/DVL1/KCNAB1/NCF1/VTI1B/DRP2/GDPD5/AURKA/ATXN10/ELOVL5/BRINP1/TXN2	75
CC	GO:0055037	recycling endosome	32/2169	176/19717	0.002951	0.02756	0.02308	MICALL1/HLA-F/HLA-A/PDLIM4/HLA-C/RAB8A/ANK2/MCTP1/ABCG1/KCNK1/HLA-G/ACKR3/ACAP1/ITSN1/TFRC/AMOTL2/HLA-E/ATP9A/SLC31A2/HLA-B/EHD4/TMEM230/DYNC1I1/VPS16/FZD7/HFE/BACE1/CLIP3/VTI1B/RAB11FIP2/RAB14/RAB11FIP1	32
CC	GO:0031901	early endosome membrane	28/2169	149/19717	0.003215	0.02928	0.02452	LRP6/HLA-F/HLA-A/PDLIM4/NTRK2/HLA-C/HLA-G/CLCN4/WLS/EGFR/HLA-E/ATP9A/SPHK1/HLA-B/FCGR1B/EHD4/EPHB1/PMEPA1/SNX5/LDLRAD4/KIF16B/OR51E2/CLIP3/MTMR2/VTI1B/SH3GL3/RAB14/PML	28
CC	GO:0030665	clathrin-coated vesicle membrane	23/2169	115/19717	0.003217	0.02928	0.02452	CD3D/AP1G2/BTC/IL7R/CD74/TBC1D5/CD3G/NECAP2/SLC18A2/TFRC/EGFR/HBEGF/HLA-DRA/HLA-DPB1/DENND1A/FCGR1B/FZD4/CD9/HLA-DQB2/VAMP2/SCARB2/HLA-DPA1/FZD2	23
CC	GO:0000778	condensed nuclear chromosome kinetochore	6/2169	15/19717	0.003654	0.03284	0.0275	BUB1/NDC80/PLK1/BUB1B/CCNB1/REC8	6
CC	GO:0002102	podosome	9/2169	30/19717	0.00386	0.03411	0.02856	LCP1/LPXN/BIN2/ADAM8/SH3PXD2A/CTTN/WDR1/GSN/ACTR2	9
CC	GO:0001726	ruffle	31/2169	172/19717	0.00389	0.03411	0.02856	LCP1/PLEKHA1/PLEKHO1/SH2B2/ITGB1BP1/SAMSN1/ARHGEF26/COBL/FGR/PDPN/DLC1/SH3YL1/PLEK/MTMR14/SKAP1/DDX58/SNX5/PSD3/KANK1/PAK1/MYO1C/PSD4/CTTN/IFIT5/CFL1/TESC/FERMT1/WASF2/ITGAV/ATP6V1B2/GSN	31
CC	GO:0045171	intercellular bridge	14/2169	59/19717	0.004082	0.03536	0.02961	GSTM5/GSTM3/TPX2/CDCA8/CEP55/KIF4A/KRR1/KIF20A/CDC7/MICAL1/PKNOX2/GSTM2/THOC1/KIF23	14
CC	GO:0045177	apical part of cell	59/2169	384/19717	0.005088	0.04355	0.03647	DDR2/DYNC2LI1/MREG/ASPM/PARD3/ANK2/ARHGEF18/KCNK1/EMP2/TCIRG1/FXYD1/SLC26A2/CD36/SLC29A1/AMOTL2/EGFR/PDPN/CSPG4/ERBB2/KCNK2/AHCYL1/PLD1/SORBS2/PLAT/NOX4/CDH2/DCHS1/SLC7A5/ATP1B1/RAB27A/CEACAM5/CA2/KL/CD9/NOTCH1/STXBP2/SLC12A2/HSP90AB1/P2RY6/ACVR1/CLIC5/HFE/FZD6/FAT4/IFIT5/CYBA/NOD1/IGFBP2/SLC23A2/SNX10/REN/PTH1R/CLCN5/ATP6V1B2/SLC2A5/TRPM6/P2RY4/PRKG2/CHL1	59
CC	GO:0070821	tertiary granule membrane	16/2169	73/19717	0.005158	0.04363	0.03654	TMC6/LILRB2/ITGB2/LILRA3/ADAM8/CD93/PLD1/CD53/SLC2A3/ITGAX/TSPAN14/FPR2/CYBA/ADAM10/NBEAL2/RAB14	16
CC	GO:0030479	actin cortical patch	6/2169	16/19717	0.005307	0.04374	0.03663	WASL/WAS/GMFG/CAPZA1/ACTR3/ACTR2	6
CC	GO:0061645	endocytic patch	6/2169	16/19717	0.005307	0.04374	0.03663	WASL/WAS/GMFG/CAPZA1/ACTR3/ACTR2	6
CC	GO:0005770	late endosome	42/2169	256/19717	0.005353	0.04374	0.03663	LAMP3/MICALL1/MREG/CST7/CXCR4/CD74/TCIRG1/CLCN4/DYSF/DYNC1LI2/CDIP1/CTSL/MMD/EGFR/NPC1/SLC31A2/HLA-DRA/MAGI2/PLD1/TMEM230/HLA-DMA/VPS16/HLA-DMB/RAB27A/VPS37C/YIPF1/BACE1/SCARB2/CHMP2B/DDIT3/AP1AR/OSBPL1A/SDF4/ABHD6/OSBPL9/FYCO1/VTI1B/STOML1/PARM1/RAB14/CHMP1B/CTSH	42
CC	GO:0005788	endoplasmic reticulum lumen	49/2169	309/19717	0.005519	0.04458	0.03733	COLGALT2/SERPINA1/BMP4/IGFBP5/PENK/WNT5B/CLU/TMEM43/APOL1/STS/MXRA8/CTSC/PDGFD/CFP/CP/SCG2/ERAP2/PRSS23/COL8A2/DAG1/ESD/F5/SPON1/COL8A1/COL14A1/CRTAP/VCPIP1/CDH2/VCAN/LRPAP1/COL15A1/CHRDL1/RCN2/FKBP14/FLT3/TSPAN14/BACE1/IL6/SDF2L1/RCN3/APLP2/ADAM10/RCN1/FSTL3/EDEM2/LIPC/CALU/COL16A1/FKBP10	49
CC	GO:0005871	kinesin complex	13/2169	55/19717	0.005748	0.04592	0.03845	KIF11/KIF15/KIF18B/KIF3B/KIF21B/KIF2C/KIF4A/KIF20A/KIF16B/KIF20B/KIFC1/KIF1B/KIF23	13
CC	GO:0032587	ruffle membrane	19/2169	94/19717	0.006225	0.04918	0.04119	LCP1/PLEKHA1/PLEKHO1/FGR/PDPN/DLC1/SH3YL1/PLEK/DDX58/PSD3/KANK1/PAK1/MYO1C/PSD4/IFIT5/CFL1/TESC/FERMT1/ITGAV	19
CC	GO:1904949	ATPase complex	20/2169	101/19717	0.006453	0.05043	0.04223	ING3/FXYD1/BAZ1A/SMARCA1/BPTF/SMARCD3/PLN/ATP1B1/SMARCC2/SMARCA2/VCP/ATP1A2/SMARCD1/CHD4/ACTR8/SUZ12/PHF10/RSF1/RB1/SS18	20
CC	GO:0035580	specific granule lumen	14/2169	62/19717	0.006527	0.05046	0.04226	SLPI/CXCL1/CFP/LYZ/TIMP2/PTPN6/NFKB1/QPCT/RAB27A/DOCK2/FRK/HP/CANT1/PTX3	14
CC	GO:0030669	clathrin-coated endocytic vesicle membrane	11/2169	44/19717	0.006865	0.05159	0.04321	CD74/TBC1D5/HBEGF/HLA-DRA/HLA-DPB1/FCGR1B/FZD4/CD9/HLA-DQB2/HLA-DPA1/FZD2	11
CC	GO:0014704	intercalated disc	12/2169	50/19717	0.006875	0.05159	0.04321	ANK2/FXYD1/FGF13/CDH2/KCNJ2/ATP1B1/SCN1B/DSC2/ATP1A2/SLC8A1/PAK1/GJC1	12
CC	GO:0005942	phosphatidylinositol 3-kinase complex	8/2169	27/19717	0.006889	0.05159	0.04321	PIK3R1/SOCS1/CISH/SOCS2/PIK3CD/SOCS6/PIK3CA/PIK3R3	8
CC	GO:0044853	plasma membrane raft	21/2169	109/19717	0.007379	0.0541	0.0453	LRP6/CD8A/ADD3/LCP2/ITGB2/FXYD1/BMPR1A/JAK2/DAG1/DLC1/SELE/CDH2/SKAP1/MS4A1/HTR2A/ATP1B1/EFNA5/ATP1A2/SELPLG/TFPI/HCK	21
CC	GO:0097038	perinuclear endoplasmic reticulum	7/2169	22/19717	0.007401	0.0541	0.0453	PIK3R1/CLU/CREB3L2/NOX4/CYBA/ADAM10/GDPD5	7
CC	GO:0031092	platelet alpha granule membrane	6/2169	17/19717	0.007449	0.0541	0.0453	CD36/PHACTR2/CYB5R1/CD9/PECAM1/APLP2	6
CC	GO:0030136	clathrin-coated vesicle	32/2169	188/19717	0.008121	0.05839	0.0489	CD3D/AP1G2/CTLA4/BTC/DENND1C/IL7R/RAB8A/CD74/TBC1D5/CD3G/NECAP2/SLC18A2/TFRC/EGFR/HBEGF/HLA-DRA/HLA-DPB1/DENND1A/FCGR1B/VPS16/FZD4/RAB27A/CD9/HLA-DQB2/VAMP2/SCARB2/HLA-DPA1/DVL1/STX6/FZD2/LMBRD1/RAB14	32
CC	GO:0044291	cell-cell contact zone	15/2169	71/19717	0.00941	0.06699	0.0561	PCDH9/ANK2/JAM3/FXYD1/FGF13/CDH2/KCNJ2/ATP1B1/SCN1B/DSC2/PECAM1/ATP1A2/SLC8A1/PAK1/GJC1	15
CC	GO:0030315	T-tubule	12/2169	52/19717	0.009514	0.06707	0.05616	SRI/CACNA2D1/ANK2/FXYD1/DYSF/KCNJ5/KCNJ2/SCN1B/AHNAK2/ATP1A2/SLC8A1/TGFB3	12
CC	GO:0000792	heterochromatin	16/2169	78/19717	0.009956	0.0695	0.0582	FOXC1/SIRT7/UBE2B/CENPB/DNMT1/ATRX/PHC2/MECP2/MPHOSPH8/CBX1/SUZ12/HELLS/DDX6/HMGA1/IKZF1/PML	16
CC	GO:0005798	Golgi-associated vesicle	30/2169	178/19717	0.0116	0.08017	0.06714	COPZ2/SERPINA1/AP1G2/HLA-F/HLA-A/HLA-C/RAB8A/CD74/HLA-G/CTSC/GOLGA2/HLA-E/YIPF6/F5/HLA-DRA/HLA-DPB1/HLA-B/SEC31A/YIPF5/KDELR3/HLA-DQB2/KDELR2/BACE1/HLA-DPA1/ADAM10/ERGIC2/VTI1B/CNIH1/SEC23B/RAB14	30
CC	GO:0000793	condensed chromosome	36/2169	223/19717	0.01199	0.08208	0.06874	ADD3/MKI67/BUB1/NCAPD2/NDC80/MAD2L1/SMC6/PLK1/NCAPH/BLM/HJURP/NCAPG/ZNF207/STAG2/BUB1B/KIF2C/DYNC1I1/CENPB/TOP2A/NEK2/ATRX/BRD4/SPC25/ZWINT/STAG3/CCNB1/DCTN6/CENPF/REC8/AURKB/ERCC6L/SMC4/CENPM/SETMAR/AURKA/TOPBP1	36
CC	GO:0016514	SWI/SNF complex	6/2169	19/19717	0.01348	0.09142	0.07656	SMARCD3/SMARCC2/SMARCA2/SMARCD1/RB1/SS18	6
CC	GO:0061702	inflammasome complex	5/2169	14/19717	0.01369	0.092	0.07704	AIM2/CASP1/CASP5/CASP4/NLRP3	5
CC	GO:0101003	ficolin-1-rich granule membrane	13/2169	61/19717	0.01399	0.09311	0.07797	LILRB2/TCIRG1/ITGB2/LILRA3/ADAM8/CR1/CD93/NCKAP1L/SLC2A3/FPR1/ITGAX/FPR2/NBEAL2	13
CC	GO:0055038	recycling endosome membrane	16/2169	81/19717	0.01421	0.09373	0.0785	MICALL1/HLA-F/HLA-A/PDLIM4/HLA-C/RAB8A/HLA-G/ACAP1/HLA-E/HLA-B/EHD4/FZD7/CLIP3/VTI1B/RAB11FIP2/RAB14	16
CC	GO:0005875	microtubule associated complex	26/2169	152/19717	0.01492	0.09755	0.08169	DYNC2LI1/MAP4/EML1/RABGAP1/DYNC1LI2/KIF11/CDCA8/KIF15/KIF18B/KIF3B/TPR/KIF21B/KIF2C/KIF4A/DYNC1I1/KIF20A/KIF16B/DCTN6/MAP1B/AURKB/KIF20B/DYNLRB1/AURKA/KIFC1/KIF1B/KIF23	26
CC	GO:0043209	myelin sheath	11/2169	49/19717	0.01566	0.1014	0.08495	PLP1/JAM3/AKR1B1/PMP22/ERBB2/TUBB4A/CA2/GDI1/STX4/MPP5/GSN	11
CC	GO:0070603	SWI/SNF superfamily-type complex	15/2169	76/19717	0.01736	0.1111	0.09303	ING3/BAZ1A/SMARCA1/BPTF/SMARCD3/SMARCC2/SMARCA2/SMARCD1/CHD4/ACTR8/SUZ12/PHF10/RSF1/RB1/SS18	15
CC	GO:0005721	pericentric heterochromatin	6/2169	20/19717	0.0175	0.1111	0.09303	CENPB/DNMT1/ATRX/CBX1/HELLS/IKZF1	6
CC	GO:0031010	ISWI-type complex	4/2169	10/19717	0.01777	0.1111	0.09303	BAZ1A/SMARCA1/BPTF/RSF1	4
CC	GO:0097197	tetraspanin-enriched microdomain	4/2169	10/19717	0.01777	0.1111	0.09303	PDPN/TSPAN14/ADAM10/CD81	4
CC	GO:0000790	nuclear chromatin	55/2169	377/19717	0.01792	0.1111	0.09303	IRF1/RUNX3/TRPS1/STAT1/ING3/FOXC1/NUCKS1/IRF4/SIRT7/AR/BAZ1A/TRIM24/UBE2B/USP3/CREBBP/SMARCA1/BPTF/CPSF6/SMARCD3/TCF7/SP1/TCF7L2/EZH2/TP63/CENPB/CBX7/SMAD3/SMARCC2/SMARCA2/ATRX/TIMELESS/HEY2/ASF1B/MPHOSPH8/SMARCD1/CBX1/CHD4/KAT6B/SPI1/ACTR8/NIPBL/CALCOCO1/SUZ12/FER/PHF10/NR1H3/RSF1/RB1/CHAF1B/MORF4L1/RAD51AP1/IKZF1/SS18/TP53/NRIP1	55
CC	GO:0045334	clathrin-coated endocytic vesicle	13/2169	63/19717	0.01815	0.1115	0.09339	CTLA4/CD74/TBC1D5/HBEGF/HLA-DRA/HLA-DPB1/FCGR1B/FZD4/CD9/HLA-DQB2/HLA-DPA1/FZD2/LMBRD1	13
CC	GO:0045120	pronucleus	5/2169	15/19717	0.01871	0.114	0.09547	CCNA2/EZH2/CBX1/CENPF/AURKA	5
CC	GO:0031256	leading edge membrane	28/2169	170/19717	0.01915	0.1157	0.09691	LCP1/PLEKHA1/PLEKHO1/GABARAPL1/ANTXR1/FERMT2/WLS/FGR/PDPN/DLC1/SH3YL1/CSPG4/PLEK/SGCE/DDX58/PSD3/VASP/KANK1/PAK1/MYO1C/PSD4/SLC39A6/IFIT5/CFL1/TESC/FERMT1/ITGAV/SPTBN1	28
CC	GO:0016324	apical plasma membrane	47/2169	318/19717	0.0219	0.1288	0.1078	DDR2/MREG/ASPM/PARD3/ANK2/ARHGEF18/KCNK1/EMP2/TCIRG1/FXYD1/SLC26A2/CD36/SLC29A1/AMOTL2/EGFR/PDPN/CSPG4/ERBB2/KCNK2/AHCYL1/PLD1/SORBS2/NOX4/CDH2/SLC7A5/ATP1B1/RAB27A/CEACAM5/KL/CD9/NOTCH1/STXBP2/SLC12A2/HSP90AB1/P2RY6/CLIC5/FZD6/CYBA/NOD1/IGFBP2/SLC23A2/PTH1R/ATP6V1B2/SLC2A5/TRPM6/P2RY4/PRKG2	47
CC	GO:0000794	condensed nuclear chromosome	18/2169	99/19717	0.02193	0.1288	0.1078	ADD3/BUB1/NCAPD2/NDC80/PLK1/NCAPH/BLM/BUB1B/CENPB/NEK2/ATRX/BRD4/STAG3/CCNB1/REC8/AURKB/AURKA/TOPBP1	18
CC	GO:0016605	PML body	18/2169	99/19717	0.02193	0.1288	0.1078	ZBTB16/ELF4/SKI/SMC6/CHFR/BLM/ISG20/EIF3E/TCF7L2/ATRX/ARNTL/RB1/HIPK2/TP53/USP7/TOPBP1/PML/THAP1	18
CC	GO:0000776	kinetochore	23/2169	135/19717	0.02203	0.1288	0.1078	BUB1/NDC80/MAD2L1/DYNC1LI2/PLK1/HJURP/TPR/ZNF207/BUB1B/KIF2C/NUP160/DYNC1I1/NEK2/SPC25/ZWINT/CCNB1/DCTN6/CENPF/REC8/TTK/AURKB/ERCC6L/CENPM	23
CC	GO:0035861	site of double-strand break	12/2169	58/19717	0.02224	0.129	0.108	SMC6/WAS/RNF138/VCP/TIMELESS/PARP1/ARPC1A/SETMAR/ACTR3/SMCHD1/TP53/ACTR2	12
CC	GO:0033267	axon part	55/2169	382/19717	0.02264	0.1302	0.1091	PCDH9/UCHL1/PENK/TNFRSF1B/MYH10/ITGA4/SRI/NTRK2/PARD3/ANK2/SPOCK1/PRKCB/AUTS2/SIGMAR1/TRAK2/TPX2/ITSN1/TIMP2/COBL/SLC18A2/DNM1/DAG1/PDYN/KIF3B/FGF13/TRPV2/KIF21B/KCNK2/TUBB4A/KIF4A/SOD1/UNC5C/ZPR1/SCN1B/FEZ1/MYOC/MICAL1/HSP90AB1/DPYSL3/HSPB1/CTTN/PINK1/MAP1B/ARHGAP4/SYBU/ANG/CRTAC1/DVL1/KIF20B/KCNAB1/GDPD5/NDRG2/AURKA/SPTBN1/KIF1B	55
CC	GO:0001891	phagocytic cup	7/2169	27/19717	0.02367	0.1351	0.1131	LCP1/CORO1A/BIN2/ARHGAP25/SNX5/RAB11FIP2/ARHGAP12	7
CC	GO:0035098	ESC/E(Z) complex	5/2169	16/19717	0.0248	0.1404	0.1176	EZH2/MTF2/SUZ12/JARID2/EZH1	5
CC	GO:0005885	Arp2/3 protein complex	4/2169	11/19717	0.02554	0.1423	0.1192	ARPC5L/ARPC1A/ACTR3/ACTR2	4
CC	GO:0072687	meiotic spindle	4/2169	11/19717	0.02554	0.1423	0.1192	ASPM/BORA/FBXO5/AURKA	4
CC	GO:0016460	myosin II complex	6/2169	22/19717	0.02785	0.154	0.129	LIMCH1/MYH10/MYL5/MYH11/MYL9/MYL6B	6
CC	GO:0031904	endosome lumen	8/2169	34/19717	0.02821	0.1549	0.1297	PRF1/PDLIM4/JAK2/CTSL/LRPAP1/CTSB/PRL/CTSH	8
CC	GO:0034399	nuclear periphery	22/2169	131/19717	0.02863	0.156	0.1306	RUNX1T1/LMNB1/JAK2/NUP93/DAG1/BLM/SRPK1/TPR/STAG2/KIF4A/LRIF1/GFI1/SORBS1/CENPF/CFL1/LMNA/PPIG/THOC1/TP53/CASK/ALOX5/PML	22
CC	GO:0030427	site of polarized growth	28/2169	176/19717	0.02897	0.1566	0.1312	PCDH9/MYH10/ITGA4/PARD3/AUTS2/HCLS1/SIGMAR1/TRAK2/TIMP2/COBL/FGF13/TRPV2/KIF21B/UNC5C/ZPR1/FEZ1/HSP90AB1/DPYSL3/CTTN/PINK1/MAP1B/ARHGAP4/ANG/CRTAC1/DVL1/KIF20B/GDPD5/NDRG2	28
CC	GO:0044448	cell cortex part	29/2169	184/19717	0.02976	0.1597	0.1337	EPB41L2/CORO1A/TMOD1/COTL1/HCLS1/WASL/GYPC/DLC1/CALD1/SELE/WAS/ASPH/LANCL2/GMFG/CDH2/CAP2/DSTN/HFE/KRT19/CTTN/AKAP13/CFL1/CAPZA1/PKD2/WDR1/ACTR3/SPTBN1/GSN/ACTR2	29
CC	GO:0043197	dendritic spine	27/2169	169/19717	0.03007	0.1602	0.1341	CD3E/MYH10/PDLIM4/SRI/DOCK10/NTRK2/RAB8A/PPP3CA/LPAR1/LAMA2/CRYAB/ITSN1/DNM1/NLGN1/CLSTN1/KCNJ2/PPP1CA/ATP1A2/SLC8A1/STX4/CTTN/MAP1B/ADAM10/DVL1/ABI2/MTMR2/PALMD	27
CC	GO:0005720	nuclear heterochromatin	8/2169	35/19717	0.03316	0.1753	0.1468	FOXC1/SIRT7/CENPB/ATRX/MPHOSPH8/CBX1/SUZ12/IKZF1	8
CC	GO:0005635	nuclear envelope	64/2169	464/19717	0.03369	0.1763	0.1477	NELL1/LBR/TMC6/IL15RA/GCH1/RAC2/TMEM43/LTC4S/DTL/CCND2/CETN2/LMNB1/SIGMAR1/MX2/LRMP/MAD2L1/NUP93/ITSN1/EGFR/NPC1/IFI27/RAB40B/TPR/PGRMC2/NUP160/TMPO/PLA2G4C/SMAD3/TNMD/GPX4/TOR1AIP1/WTAP/CETN3/DPY19L4/PAK1/MYO1C/PHLPP1/EDNRB/PARP1/SCRN1/CENPF/SLC29A2/IPO7/ANXA4/DUSP2/LMNA/RETSAT/NUP88/UNC50/MX1/ATRAID/NUP50/BNIP3L/MVP/KLHDC2/ALOX5/DNAJC2/CERS4/XPO4/UTP18/PRKG2/SPIN1/SCAI/ATP2A3	64
CC	GO:0030426	growth cone	27/2169	171/19717	0.0343	0.1763	0.1477	PCDH9/MYH10/ITGA4/PARD3/AUTS2/SIGMAR1/TRAK2/TIMP2/COBL/FGF13/TRPV2/KIF21B/UNC5C/ZPR1/FEZ1/HSP90AB1/DPYSL3/CTTN/PINK1/MAP1B/ARHGAP4/ANG/CRTAC1/DVL1/KIF20B/GDPD5/NDRG2	27
CC	GO:0044309	neuron spine	27/2169	171/19717	0.0343	0.1763	0.1477	CD3E/MYH10/PDLIM4/SRI/DOCK10/NTRK2/RAB8A/PPP3CA/LPAR1/LAMA2/CRYAB/ITSN1/DNM1/NLGN1/CLSTN1/KCNJ2/PPP1CA/ATP1A2/SLC8A1/STX4/CTTN/MAP1B/ADAM10/DVL1/ABI2/MTMR2/PALMD	27
CC	GO:0030175	filopodium	18/2169	104/19717	0.03433	0.1763	0.1477	LCP1/KITLG/ANTXR1/HLA-G/PDPN/DAG1/DEF6/FGF13/ENAH/NLGN1/EPHB1/UNC5C/VASP/ARL4C/MYO3A/ABI2/ITGAV/IQGAP2	18
CC	GO:0044615	nuclear pore nuclear basket	4/2169	12/19717	0.03504	0.1774	0.1486	CETN2/MAD2L1/TPR/CETN3	4
CC	GO:1990909	Wnt signalosome	4/2169	12/19717	0.03504	0.1774	0.1486	LRP6/RECK/LRP5/DVL1	4
CC	GO:0031902	late endosome membrane	22/2169	134/19717	0.03588	0.1804	0.1511	LAMP3/MICALL1/MREG/CLCN4/CDIP1/MMD/NPC1/HLA-DRA/PLD1/HLA-DMA/VPS16/HLA-DMB/RAB27A/VPS37C/YIPF1/SCARB2/CHMP2B/ABHD6/OSBPL9/VTI1B/STOML1/CHMP1B	22
CC	GO:0000777	condensed chromosome kinetochore	18/2169	105/19717	0.03733	0.1864	0.1561	BUB1/NDC80/MAD2L1/PLK1/HJURP/ZNF207/BUB1B/KIF2C/DYNC1I1/NEK2/SPC25/ZWINT/CCNB1/DCTN6/CENPF/REC8/ERCC6L/CENPM	18
CC	GO:0035578	azurophil granule lumen	16/2169	91/19717	0.03896	0.1932	0.1618	GCA/SERPINA3/CTSC/LYZ/PLAC8/CYB5R3/VCP/MNDA/FUCA1/PRDX6/FABP5/FRK/C6orf120/GLA/MAN2B1/ACTR2	16
CC	GO:0031527	filopodium membrane	5/2169	18/19717	0.04045	0.1992	0.1668	ANTXR1/HLA-G/PDPN/VASP/ITGAV	5
CC	GO:0030660	Golgi-associated vesicle membrane	19/2169	114/19717	0.0426	0.2083	0.1745	COPZ2/AP1G2/HLA-F/HLA-A/HLA-C/CD74/HLA-G/HLA-E/HLA-DRA/HLA-DPB1/HLA-B/SEC31A/KDELR3/HLA-DQB2/KDELR2/HLA-DPA1/VTI1B/CNIH1/SEC23B	19
CC	GO:0043034	costamere	5/2169	19/19717	0.05008	0.2433	0.2037	SYNM/ANK2/DAG1/AHNAK2/KRT19	5
CC	GO:0016363	nuclear matrix	18/2169	109/19717	0.05126	0.2473	0.2071	RUNX1T1/LMNB1/JAK2/BLM/SRPK1/STAG2/KIF4A/LRIF1/GFI1/SORBS1/CENPF/CFL1/PPIG/THOC1/TP53/CASK/ALOX5/PML	18
CC	GO:0031253	cell projection membrane	48/2169	345/19717	0.05218	0.2492	0.2087	LCP1/PLEKHA1/PLEKHO1/GABARAPL1/TMEM231/ANTXR1/KCNK1/CYBRD1/FERMT2/SLC26A2/MXRA8/HLA-G/WLS/CD36/FGR/PCDHB13/PDPN/DHRS3/DLC1/SH3YL1/CSPG4/PLEK/SGCE/DDX58/PSD3/VASP/KANK1/HSP90AB1/PAK1/MYO1C/PHLPP1/BBS1/PSD4/PEX19/SLC39A6/IFIT5/CFL1/TESC/FERMT1/GUCA1A/PKD2/PTH1R/ROM1/ITGAV/SLC5A6/CASK/TRPM6/SPTBN1	48
CC	GO:0016323	basolateral plasma membrane	32/2169	217/19717	0.05233	0.2492	0.2087	ENPP1/ANK2/ABCC4/AQP9/NOD2/SLC29A1/TFRC/EGFR/PDPN/DAG1/ERBB2/CDH2/CADM1/ATP1B1/CEACAM5/CA2/HSP90AB1/MYO1C/STX4/P2RY6/CNNM2/SLC29A2/CD38/NOD1/SLC27A5/SLC23A2/PKD2/CA11/CD81/PTH1R/CASK/P2RY4	32
CC	GO:0090734	site of DNA damage	13/2169	73/19717	0.05385	0.2547	0.2133	SMC6/WAS/RNF138/VCP/TIMELESS/CBX1/PARP1/ARPC1A/SETMAR/ACTR3/SMCHD1/TP53/ACTR2	13
CC	GO:0031941	filamentous actin	7/2169	32/19717	0.05546	0.2579	0.2159	PDLIM4/PDLIM5/PDLIM1/MYO1C/DPYSL3/PKD2/MYO3A	7
CC	GO:0032839	dendrite cytoplasm	7/2169	32/19717	0.05546	0.2579	0.2159	GABARAPL1/PURA/WLS/TRAK2/ADA/SOD1/KCNAB1	7
CC	GO:0043292	contractile fiber	34/2169	234/19717	0.05559	0.2579	0.2159	IDO1/SCO2/PDLIM4/SYNM/TMOD1/SRI/PDE4DIP/ANK2/PPP3CA/TIMP4/FERMT2/CRYAB/HDAC4/DAG1/CALD1/SORBS2/PDLIM5/PARVA/FHL5/LMOD1/AHNAK2/PDLIM1/PECAM1/MYL5/SLC8A1/PAK1/ITGB1BP2/KRT19/HSPB1/MYH11/RYR3/MYL9/MYL6B/SPTBN1	34
CC	GO:0000346	transcription export complex	4/2169	14/19717	0.05936	0.2684	0.2248	THOC2/DDX39A/THOC1/THOC6	4
CC	GO:0010369	chromocenter	4/2169	14/19717	0.05936	0.2684	0.2248	CDCA8/CBX1/SCMH1/AURKB	4
CC	GO:0031089	platelet dense granule lumen	4/2169	14/19717	0.05936	0.2684	0.2248	TIMP3/CTSW/FAM3C/CDC37L1	4
CC	GO:0043218	compact myelin	4/2169	14/19717	0.05936	0.2684	0.2248	JAM3/AKR1B1/PMP22/MPP5	4
CC	GO:0005667	transcription factor complex	50/2169	365/19717	0.06049	0.2718	0.2276	RUNX3/TFDP2/HOXA10/SOX9/PBX3/SKI/MEIS1/ZFHX3/HCLS1/SIX1/SIX2/YAP1/E2F8/TAF7/TCF7/TCF7L2/SOX2/PITX1/PBX1/LEF1/RCOR3/SMAD3/TAF1A/ARNTL/GTF2F1/ARNT/TCF7L1/PDLIM1/NFYA/HSP90AB1/PARP1/GTF2A1/SPI1/WWTR1/IVNS1ABP/DDIT3/NR1H3/RB1/CEBPA/HIPK2/HMGA1/MED14/ASCC1/ERCC1/HOXA11/TP53/TEAD4/THRA/GTF2H5/SNAPC1	50
CC	GO:0005868	cytoplasmic dynein complex	5/2169	20/19717	0.06094	0.2722	0.2279	DYNC2LI1/DYNC1LI2/TPR/DYNC1I1/DYNLRB1	5
CC	GO:0044304	main axon	12/2169	68/19717	0.06598	0.2928	0.2452	TNFRSF1B/PARD3/ANK2/SPOCK1/DNM1/DAG1/TUBB4A/SCN1B/MYOC/MAP1B/KCNAB1/SPTBN1	12
CC	GO:0031301	integral component of organelle membrane	31/2169	214/19717	0.0672	0.2964	0.2482	LBR/SCO2/TMEM43/VOPP1/SLC22A17/BID/ARMCX3/PEX26/NPC1/MPC2/BAK1/CLSTN1/STX16/AFG3L2/COX11/MICU1/APOOL/PTPRS/SLC25A4/PINK1/TPST1/MAN1C1/SGMS1/MPC1/ENTPD4/EMC6/UNC50/ERGIC2/STX6/SLC35A2/PCSK7	31
CC	GO:0031519	PcG protein complex	9/2169	47/19717	0.06771	0.2968	0.2486	SKP1/EZH2/CBX7/PHC2/MTF2/SUZ12/JARID2/EZH1/UBAP2L	9
CC	GO:0098802	plasma membrane receptor complex	41/2169	295/19717	0.06908	0.301	0.2521	CSF2RB/TRAF3/CD3D/TRAC/TRBC1/CD3E/CD247/ITGB7/CD8A/IL2RB/ITGA4/TRDV3/TRAT1/TLR2/ITGB2/CD3G/BMPR1A/CD40/TFRC/PTPN6/ITGBL1/ITGAL/ZAP70/NLGN1/SKAP1/CD6/CHRNA5/ITGA10/IL6ST/SYK/ACVR1/SORBS1/ITGAX/HFE/IL6/ABHD6/LYN/IL2RA/ITGAV/TLR6/ITGAE	41
CC	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	15/2169	91/19717	0.0715	0.3097	0.2593	LCK/GNG12/GNAL/CYTH1/FERMT2/FGR/PLEKHA4/SNX5/RACGAP1/FRK/FER/RGS1/LYN/HCK/KCNAB1	15
CC	GO:0042827	platelet dense granule	5/2169	21/19717	0.07303	0.3118	0.2611	TIMP3/ABCC4/CTSW/FAM3C/CDC37L1	5
CC	GO:0033268	node of Ranvier	4/2169	15/19717	0.07415	0.3118	0.2611	SPOCK1/DAG1/SCN1B/MYOC	4
CC	GO:0043020	NADPH oxidase complex	4/2169	15/19717	0.07415	0.3118	0.2611	NCF4/NOX4/CYBA/NCF1	4
CC	GO:0071565	nBAF complex	4/2169	15/19717	0.07415	0.3118	0.2611	SMARCD3/SMARCC2/SMARCA2/SMARCD1	4
CC	GO:0090533	cation-transporting ATPase complex	4/2169	15/19717	0.07415	0.3118	0.2611	FXYD1/PLN/ATP1B1/ATP1A2	4
CC	GO:0005766	primary lysosome	23/2169	155/19717	0.08409	0.3495	0.2927	CPNE3/GCA/SERPINA3/LRMP/CTSC/LYZ/PLAC8/ATP8A1/CYB5R3/MAGT1/VCP/FPR1/MNDA/STXBP2/FUCA1/PRDX6/FABP5/FRK/C6orf120/GLA/MAN2B1/MANBA/ACTR2	23
CC	GO:0042582	azurophil granule	23/2169	155/19717	0.08409	0.3495	0.2927	CPNE3/GCA/SERPINA3/LRMP/CTSC/LYZ/PLAC8/ATP8A1/CYB5R3/MAGT1/VCP/FPR1/MNDA/STXBP2/FUCA1/PRDX6/FABP5/FRK/C6orf120/GLA/MAN2B1/MANBA/ACTR2	23
CC	GO:0090575	RNA polymerase II transcription factor complex	24/2169	163/19717	0.08464	0.3497	0.2929	RUNX3/TFDP2/YAP1/E2F8/TAF7/TCF7L2/PBX1/LEF1/SMAD3/GTF2F1/ARNT/NFYA/GTF2A1/DDIT3/NR1H3/RB1/CEBPA/HIPK2/HMGA1/MED14/ERCC1/TP53/THRA/GTF2H5	24
CC	GO:0019867	outer membrane	29/2169	203/19717	0.08559	0.3517	0.2945	GK/ANKH/BCL2A1/LTC4S/BID/SIGMAR1/ARMCX3/BPHL/ARMCX1/CYB5R3/IFI27/BAK1/MAOA/ACACB/BCL2L2/PMAIP1/MYOC/KMO/ARMCX2/AKAP1/PINK1/MAOB/FOXO3/STARD7/RETSAT/BNIP3L/ACSL5/MOAP1/SNN	29
CC	GO:0016461	unconventional myosin complex	3/2169	10/19717	0.08841	0.3543	0.2967	MYO1F/MYO1C/MYL6B	3
CC	GO:0070938	contractile ring	3/2169	10/19717	0.08841	0.3543	0.2967	DAG1/PRC1/KIF20B	3
CC	GO:0072546	ER membrane protein complex	3/2169	10/19717	0.08841	0.3543	0.2967	EMC2/EMC8/EMC6	3
CC	GO:0030133	transport vesicle	52/2169	392/19717	0.08844	0.3543	0.2967	SSPN/COPZ2/AP1G2/SYNGR2/IGF1/PENK/HLA-F/HLA-A/SLC17A5/SIPA1/HLA-C/RAB8A/MCTP1/CD74/DMXL2/PAM/HLA-G/SLC18A2/SNCAIP/DNM1/HLA-E/BGN/HLA-DRA/HLA-DPB1/HLA-B/SEC31A/STX16/TMEM230/PTPRS/CPE/RAB27A/KDELR3/YIPF1/HLA-DQB2/CPA3/SYT17/STX4/DPYSL3/VAMP2/KDELR2/BACE1/HLA-DPA1/AP1AR/ADAM10/OVGP1/HCK/STX6/MTMR2/VTI1B/CNIH1/SEC23B/RAB14	52
CC	GO:0005802	trans-Golgi network	33/2169	236/19717	0.08869	0.3543	0.2967	LAP3/NBEA/ARL1/PREPL/RAB8A/CD74/RHOBTB3/CBY1/PAM/COG5/WLS/ATP8A1/ATP9A/CHST3/YIPF6/HLA-DRA/HLA-DPB1/STX16/TMEM230/YIPF1/HLA-DQB2/SYT17/STX4/VAMP2/BACE1/HLA-DPA1/ADAM10/PRKD1/CLIP3/ATXN2/STX6/RAB14/PCSK7	33
CC	GO:0000784	nuclear chromosome, telomeric region	19/2169	125/19717	0.09063	0.36	0.3015	PURA/SIRT7/CDK1/MCM5/FEN1/ATRX/LRIF1/MCM2/PPP1CA/THOC2/TERF1/CBX1/PARP1/MCM4/ERCC1/THOC1/SMCHD1/THOC6/PML	19
CC	GO:0005796	Golgi lumen	16/2169	102/19717	0.0916	0.3613	0.3025	PRELP/FMOD/GPC5/WNT5B/OGN/DAG1/PROS1/DCN/BGN/CSPG4/RAB33B/LUM/VCAN/LRPAP1/GPC4/SDF4	16
CC	GO:1990752	microtubule end	6/2169	29/19717	0.09195	0.3613	0.3025	ASPM/MAPRE2/KIF18B/KIF2C/SKAP1/CAMSAP2	6
CC	GO:0031300	intrinsic component of organelle membrane	33/2169	237/19717	0.09264	0.3613	0.3025	LBR/MREG/SCO2/TMEM43/VOPP1/SLC22A17/BID/ARMCX3/PEX26/NPC1/MPC2/BAK1/CLSTN1/STX16/AFG3L2/COX11/MICU1/APOOL/PTPRS/SLC25A4/PINK1/TPST1/MAN1C1/SGMS1/MPC1/ENTPD4/EMC6/UNC50/ERGIC2/GOLGA7/STX6/SLC35A2/PCSK7	33
CC	GO:0005844	polysome	12/2169	72/19717	0.09325	0.3613	0.3025	MYH10/RPL31/RPL24/LARP6/DAZL/RPS4X/EIF4B/BTF3/VBP1/RWDD1/ATXN2/RPL10A	12
CC	GO:0044449	contractile fiber part	31/2169	221/19717	0.09346	0.3613	0.3025	IDO1/PDLIM4/SYNM/TMOD1/SRI/ANK2/PPP3CA/TIMP4/FERMT2/CRYAB/HDAC4/DAG1/SORBS2/PDLIM5/PARVA/FHL5/LMOD1/AHNAK2/PDLIM1/PECAM1/MYL5/SLC8A1/PAK1/ITGB1BP2/KRT19/HSPB1/MYH11/RYR3/MYL9/MYL6B/SPTBN1	31
CC	GO:0032592	integral component of mitochondrial membrane	12/2169	73/19717	0.101	0.3883	0.3252	SCO2/BID/ARMCX3/MPC2/BAK1/AFG3L2/COX11/MICU1/APOOL/SLC25A4/PINK1/MPC1	12
CC	GO:0005771	multivesicular body	9/2169	51/19717	0.1024	0.3916	0.3279	CST7/CD74/CTSL/EGFR/RAB27A/BACE1/CHMP2B/CHMP1B/CTSH	9
CC	GO:0034358	plasma lipoprotein particle	7/2169	37/19717	0.1055	0.3994	0.3345	CLU/APOL1/PCYOX1/CETP/HDLBP/LIPC/PLA2G7	7
CC	GO:1990777	lipoprotein particle	7/2169	37/19717	0.1055	0.3994	0.3345	CLU/APOL1/PCYOX1/CETP/HDLBP/LIPC/PLA2G7	7
CC	GO:0042599	lamellar body	4/2169	17/19717	0.1086	0.4086	0.3422	LAMP3/ABCA3/SPINK5/CTSH	4
CC	GO:0098573	intrinsic component of mitochondrial membrane	12/2169	74/19717	0.1091	0.4086	0.3422	SCO2/BID/ARMCX3/MPC2/BAK1/AFG3L2/COX11/MICU1/APOOL/SLC25A4/PINK1/MPC1	12
CC	GO:0098978	glutamatergic synapse	46/2169	349/19717	0.1117	0.4087	0.3423	WASF3/CORO1A/MYH10/PURA/RAB8A/PPP3CA/PFN2/USP46/PTPRD/JAK2/FXYD6/ITSN1/DNM1/DAG1/ARHGAP22/NLGN1/CLSTN1/EPHB1/PCDH17/PLAT/PTPRS/FZD4/HTR2A/ADAM22/SEMA3F/ARPC5L/VCP/PPP1CA/STX4/GPC4/STXBP1/LGI1/CHMP2B/KPNA2/ADAM10/ABHD6/LYN/ADAM23/DVL1/DRP2/PFN1/SH3GL3/SPTBN1/TANC2/P2RY4/CADPS	46
CC	GO:0005652	nuclear lamina	3/2169	11/19717	0.112	0.4087	0.3423	LMNB1/LMNA/CASK	3
CC	GO:0019774	proteasome core complex, beta-subunit complex	3/2169	11/19717	0.112	0.4087	0.3423	PSMB9/PSMB8/PSMB10	3
CC	GO:0031838	haptoglobin-hemoglobin complex	3/2169	11/19717	0.112	0.4087	0.3423	HBB/HBD/HP	3
CC	GO:0043220	Schmidt-Lanterman incisure	3/2169	11/19717	0.112	0.4087	0.3423	JAM3/AKR1B1/MPP5	3
CC	GO:0031968	organelle outer membrane	28/2169	201/19717	0.1132	0.4091	0.3426	GK/BCL2A1/LTC4S/BID/SIGMAR1/ARMCX3/BPHL/ARMCX1/CYB5R3/IFI27/BAK1/MAOA/ACACB/BCL2L2/PMAIP1/MYOC/KMO/ARMCX2/AKAP1/PINK1/MAOB/FOXO3/STARD7/RETSAT/BNIP3L/ACSL5/MOAP1/SNN	28
CC	GO:0044798	nuclear transcription factor complex	28/2169	201/19717	0.1132	0.4091	0.3426	RUNX3/TFDP2/SOX9/YAP1/E2F8/TAF7/TCF7L2/SOX2/PBX1/LEF1/SMAD3/TAF1A/GTF2F1/ARNT/NFYA/GTF2A1/DDIT3/NR1H3/RB1/CEBPA/HIPK2/HMGA1/MED14/ERCC1/TP53/THRA/GTF2H5/SNAPC1	28
CC	GO:0000781	chromosome, telomeric region	23/2169	161/19717	0.1152	0.4141	0.3468	PURA/SIRT7/SMC6/BLM/CDK1/EZH2/MCM5/FEN1/ATRX/LRIF1/MCM2/PPP1CA/THOC2/TERF1/CBX1/PARP1/MCM4/ERCC1/THOC1/EZH1/SMCHD1/THOC6/PML	23
CC	GO:0005741	mitochondrial outer membrane	25/2169	178/19717	0.1202	0.4299	0.36	GK/BCL2A1/BID/ARMCX3/BPHL/ARMCX1/CYB5R3/IFI27/BAK1/MAOA/ACACB/BCL2L2/PMAIP1/MYOC/KMO/ARMCX2/AKAP1/PINK1/MAOB/FOXO3/STARD7/BNIP3L/ACSL5/MOAP1/SNN	25
CC	GO:0009898	cytoplasmic side of plasma membrane	22/2169	154/19717	0.1212	0.4314	0.3613	TRAF3/LCK/PTPRC/CD2/GNG12/GNAL/CYTH1/PPP3CA/FERMT2/PTPN7/GEM/FGR/PLEKHA4/SNX5/RACGAP1/FRK/PTPN22/FER/RGS1/LYN/HCK/KCNAB1	22
CC	GO:0005903	brush border	15/2169	99/19717	0.1246	0.4413	0.3696	ADD3/MYH10/RALGDS/KCNK1/CYBRD1/CD36/SNX5/HSP90AB1/MYO1C/PEX19/PTH1R/ACTR3/SLC5A6/TRPM6/SOAT2	15
CC	GO:0005859	muscle myosin complex	4/2169	18/19717	0.1281	0.4485	0.3756	MYL5/MYH11/MYL9/MYL6B	4
CC	GO:0032433	filopodium tip	4/2169	18/19717	0.1281	0.4485	0.3756	NLGN1/EPHB1/MYO3A/ABI2	4
CC	GO:0017053	transcriptional repressor complex	13/2169	84/19717	0.1291	0.4485	0.3756	RELB/ZBTB16/GLI3/SKI/HDAC4/SP1/RCOR3/HEY2/CCND1/CHD4/GFI1/DEPDC1/TBL1X	13
CC	GO:0120111	neuron projection cytoplasm	13/2169	84/19717	0.1291	0.4485	0.3756	UCHL1/GABARAPL1/PURA/WLS/TRAK2/ADA/KIF3B/KIF4A/SOD1/HSPB1/SYBU/KCNAB1/KIF1B	13
CC	GO:0032994	protein-lipid complex	7/2169	39/19717	0.1307	0.4517	0.3783	CLU/APOL1/PCYOX1/CETP/HDLBP/LIPC/PLA2G7	7
CC	GO:0005905	clathrin-coated pit	11/2169	69/19717	0.1326	0.4562	0.382	LRP3/TBC1D5/NECAP2/ACKR3/ITSN1/TFRC/SPHK1/FNBP1/SELE/LRP10/CTTN	11
CC	GO:0031965	nuclear membrane	39/2169	296/19717	0.1341	0.4585	0.384	LBR/TMC6/IL15RA/GCH1/TMEM43/LTC4S/DTL/CCND2/LMNB1/SIGMAR1/NUP93/EGFR/IFI27/TPR/SMAD3/TOR1AIP1/WTAP/DPY19L4/PAK1/PHLPP1/EDNRB/SCRN1/SLC29A2/ANXA4/DUSP2/LMNA/RETSAT/UNC50/MX1/NUP50/KLHDC2/ALOX5/DNAJC2/CERS4/UTP18/PRKG2/SPIN1/SCAI/ATP2A3	39
CC	GO:0030018	Z disc	19/2169	132/19717	0.1346	0.4585	0.384	PDLIM4/SRI/ANK2/PPP3CA/CRYAB/HDAC4/SORBS2/PDLIM5/PARVA/FHL5/AHNAK2/PDLIM1/SLC8A1/PAK1/ITGB1BP2/KRT19/HSPB1/RYR3/MYL9	19
CC	GO:0005614	interstitial matrix	3/2169	12/19717	0.1376	0.4603	0.3854	KAZALD1/ECM2/NAV2	3
CC	GO:0005833	hemoglobin complex	3/2169	12/19717	0.1376	0.4603	0.3854	HBB/CYB5R3/HBD	3
CC	GO:0005890	sodium:potassium-exchanging ATPase complex	3/2169	12/19717	0.1376	0.4603	0.3854	FXYD1/ATP1B1/ATP1A2	3
CC	GO:0042555	MCM complex	3/2169	12/19717	0.1376	0.4603	0.3854	MCM5/MCM2/MCM4	3
CC	GO:0005795	Golgi stack	21/2169	149/19717	0.1408	0.4688	0.3926	RASIP1/SULF1/VRK1/GOLGA2/YIPF6/GOLGA3/VCPIP1/GAL3ST4/ASAP2/STX16/TOM1L1/YIPF1/SGMS1/CLIP3/FUT8/GOLGB1/GOLGA7/CANT1/RAB14/FUT4/B4GALT2	21
CC	GO:0005657	replication fork	11/2169	70/19717	0.1426	0.4726	0.3957	PURA/UBE2B/CDC45/BLM/HMCES/RFC3/DNMT1/DONSON/TIMELESS/TP53/MCM10	11
CC	GO:0031045	dense core granule	4/2169	19/19717	0.1489	0.4888	0.4094	PENK/ADAM8/SCG2/SOD1	4
CC	GO:0043073	germ cell nucleus	4/2169	19/19717	0.1489	0.4888	0.4094	REC8/TRIP13/AURKA/TOPBP1	4
CC	GO:0034364	high-density lipoprotein particle	5/2169	26/19717	0.1506	0.4922	0.4122	CLU/APOL1/CETP/HDLBP/LIPC	5
CC	GO:0031674	I band	20/2169	143/19717	0.1558	0.5067	0.4244	PDLIM4/SRI/ANK2/PPP3CA/FERMT2/CRYAB/HDAC4/SORBS2/PDLIM5/PARVA/FHL5/AHNAK2/PDLIM1/SLC8A1/PAK1/ITGB1BP2/KRT19/HSPB1/RYR3/MYL9	20
CC	GO:0005604	basement membrane	14/2169	95/19717	0.1575	0.5102	0.4272	TIMP3/LAMA2/EFEMP2/COL8A2/DAG1/THBS4/COL8A1/PTN/EFNA5/COL15A1/FGF9/FBLN1/ANG/CASK	14
CC	GO:0009925	basal plasma membrane	6/2169	34/19717	0.1645	0.5241	0.4389	EGFR/ERBB2/MYO1C/SLC27A5/SLC23A2/PKD2	6
CC	GO:0032045	guanyl-nucleotide exchange factor complex	3/2169	13/19717	0.165	0.5241	0.4389	RASGRP3/DOCK1/PDE3B	3
CC	GO:0036038	MKS complex	3/2169	13/19717	0.165	0.5241	0.4389	TMEM231/TCTN1/AHI1	3
CC	GO:0005901	caveola	12/2169	80/19717	0.1655	0.5241	0.4389	LRP6/FXYD1/BMPR1A/JAK2/DLC1/SELE/HTR2A/ATP1B1/EFNA5/ATP1A2/TFPI/HCK	12
CC	GO:0016528	sarcoplasm	12/2169	80/19717	0.1655	0.5241	0.4389	SRI/CACNA2D1/SPOCK1/THBS4/PLN/ASPH/SGCD/RYR3/GSTM2/CALU/GSN/ATP2A3	12
CC	GO:0097431	mitotic spindle pole	5/2169	27/19717	0.1692	0.5335	0.4467	ASPM/EML1/STAG2/KIF20B/AURKA	5
CC	GO:0035371	microtubule plus-end	4/2169	20/19717	0.1709	0.5365	0.4493	MAPRE2/KIF18B/KIF2C/SKAP1	4
CC	GO:0098562	cytoplasmic side of membrane	24/2169	178/19717	0.1717	0.5368	0.4495	TRAF3/LCK/PTPRC/CD2/GNG12/GNAL/CYTH1/PPP3CA/FERMT2/PTPN7/CDIP1/GEM/FGR/PLEKHA4/SNX5/RACGAP1/FRK/PTPN22/FER/RGS1/LYN/PKD2/HCK/KCNAB1	24
CC	GO:0005643	nuclear pore	13/2169	89/19717	0.1766	0.5495	0.4602	CETN2/MX2/MAD2L1/NUP93/TPR/NUP160/CETN3/MYO1C/IPO7/NUP88/NUP50/MVP/XPO4	13
CC	GO:0000118	histone deacetylase complex	9/2169	58/19717	0.1828	0.5642	0.4725	HDAC4/ZNF217/SAP18/HEY2/CHD4/MORF4L1/HINT1/NRIP1/TBL1X	9
CC	GO:0005637	nuclear inner membrane	9/2169	58/19717	0.1828	0.5642	0.4725	LBR/TMEM43/LMNB1/SIGMAR1/IFI27/SMAD3/TOR1AIP1/DPY19L4/UNC50	9
CC	GO:0035869	ciliary transition zone	10/2169	66/19717	0.1852	0.5689	0.4764	DYNC2LI1/TMEM231/CETN2/PCDHB13/TMEM80/C5orf30/TCTN1/ARL3/NPHP4/AHI1	10
CC	GO:0072562	blood microparticle	20/2169	147/19717	0.1869	0.5719	0.4789	CLU/APOL1/SERPINA3/HBB/CP/TFRC/PROS1/HSPA6/ZBTB38/IGHM/ANGPTL4/HBD/IGLC1/IGHG1/HP/CFB/HSPA1L/AFM/PFN1/GSN	20
CC	GO:0044295	axonal growth cone	5/2169	28/19717	0.1885	0.572	0.479	PARD3/TRAK2/COBL/TRPV2/HSP90AB1	5
CC	GO:0090543	Flemming body	5/2169	28/19717	0.1885	0.572	0.479	USP3/CEP55/RACGAP1/CNTRL/KIF23	5
CC	GO:0005767	secondary lysosome	3/2169	14/19717	0.1938	0.5809	0.4865	ADAM8/NCF4/NCF1	3
CC	GO:0000242	pericentriolar material	4/2169	21/19717	0.1939	0.5809	0.4865	LCK/NEK1/CEP85/TUBG2	4
CC	GO:0098533	ATPase dependent transmembrane transport complex	4/2169	21/19717	0.1939	0.5809	0.4865	FXYD1/PLN/ATP1B1/ATP1A2	4
CC	GO:0008180	COP9 signalosome	6/2169	36/19717	0.1987	0.5928	0.4964	EPB41L2/TMOD1/LAT/HSPA6/HSP90AB1/HSPA1L	6
MF	GO:0019955	cytokine binding	42/2095	128/17697	2.994e-10	3.272e-07	2.934e-07	IL2RG/CCR5/CRLF1/CCR2/GDF5/GBP1/IL27RA/TNFRSF1B/CXCR4/IL2RB/IL3RA/ITGA4/IL11RA/LTBP3/CCR7/CD74/ACKR3/CD36/COMP/TNFRSF14/TWSG1/PDPN/TGFBR3/GHR/CCR1/IL13RA2/CX3CR1/CXCR6/FZD4/NBL1/IL6ST/ACVR1/IL10RA/TGFB3/CCR8/LIFR/IL1RN/LRRC32/IL2RA/ITGAV/CCRL2/IL1R1	42
MF	GO:0023023	MHC protein complex binding	15/2095	25/17697	1.225e-08	6.409e-06	5.746e-06	CD8A/LILRB2/CD74/HLA-DRA/CD160/KLRD1/HLA-DMA/MS4A1/ATP1B1/HLA-DMB/TAPBPL/FAM49B/HSP90AB1/CD81/LILRB1	15
MF	GO:1901681	sulfur compound binding	61/2095	250/17697	2.151e-08	6.409e-06	5.746e-06	PRELP/CXCL13/ENPP1/PLA2G2D/NELL1/NDNF/SFRP1/PTPRC/BMP4/SERPINA5/CHST15/PCOLCE2/ACADVL/FGF7/GSTM3/ALDH6A1/CBS/ECM2/SELL/LTBP2/COMP/CXCL10/HBEGF/FGF2/TGFBR3/PC/THBS4/MCCC1/LANCL1/ZNF207/GAL3ST4/PTPRF/PTN/ACACB/PCOLCE/PTPRS/LRPAP1/PCCA/HSD17B12/NELL2/LIPG/NAV2/CXCL11/ECI2/CCL7/LXN/DPYSL3/FGF9/ANXA4/FST/CXCL6/APLP2/VEGFB/ANG/ACADL/GSTM2/PRMT1/LIPC/CCL23/SOAT2/HADHA	61
MF	GO:0004896	cytokine receptor activity	32/2095	96/17697	2.486e-08	6.409e-06	5.746e-06	CSF2RB/IL2RG/CCR5/CRLF1/CCR2/IL27RA/IL15RA/IL21R/CXCR4/IL2RB/IL3RA/IL7R/IL11RA/CCR7/CD74/IL4R/ACKR3/GHR/CCR1/IL13RA2/CX3CR1/CXCR6/FZD4/IL6ST/FLT3/IL10RA/CCR8/LIFR/GFRA2/IL2RA/CCRL2/IL1R1	32
MF	GO:0005539	glycosaminoglycan binding	57/2095	229/17697	2.932e-08	6.409e-06	5.746e-06	PRELP/CXCL13/PLA2G2D/NELL1/SUSD5/NDNF/SFRP1/PTPRC/BMP4/SPOCK2/SERPINA5/PCOLCE2/TLR2/FGF7/HMMR/SULF1/ECM2/EXTL2/SELL/NOD2/LTBP2/COMP/CXCL10/HBEGF/FGF2/TGFBR3/LYVE1/THBS4/DCN/BGN/IGHM/ZNF207/PTPRF/PTN/PCOLCE/PTPRS/VCAN/LRPAP1/HSD17B12/NELL2/LIPG/NAV2/CXCL11/CCL7/LXN/DPYSL3/FGF9/ANXA4/CXCL6/APLP2/VEGFB/ANG/NOD1/LIPC/CCL23/STAB2/NLRP3	57
MF	GO:0017124	SH3 domain binding	37/2095	130/17697	2.221e-07	3.877e-05	3.476e-05	CD3E/ADAM19/EFS/PTTG1/SH3BP5/PTTG3P/HCLS1/SH2D2A/DNM1/PTPN6/LANCL1/DENND1A/ARHGAP17/WAS/ENAH/DOCK1/SKAP1/ZNF106/TOM1L1/VASP/CCDC6/MICAL1/ITGB1BP2/DPYSL3/PTPN22/INPP5D/PLSCR1/CYBA/ADAM10/LYN/TP53BP2/WASF2/FUT8/NCF1/KHDRBS3/ABI2/KHDRBS1	37
MF	GO:0008009	chemokine activity	20/2095	49/17697	2.483e-07	3.877e-05	3.476e-05	CCL5/CXCL13/CXCL9/XCL1/CCL19/CCL13/CXCL1/CXCL10/CXCL8/CCL21/CCL18/CXCL3/CXCL11/CCL7/CXCL2/CXCL5/CXCL6/CCL17/CCL2/CCL23	20
MF	GO:0042379	chemokine receptor binding	23/2095	66/17697	9.239e-07	0.0001262	0.0001132	CCL5/CXCL13/CXCL9/XCL1/CCR2/STAT1/CCL19/CCL13/CXCL1/CXCL10/CXCL8/CCL21/CCL18/CXCL3/CXCL11/CCL7/CXCL2/CXCL5/CXCL6/CCL17/CCL2/CCRL2/CCL23	23
MF	GO:0004715	non-membrane spanning protein tyrosine kinase activity	18/2095	46/17697	2.057e-06	0.0002498	0.0002239	ITK/LCK/CSK/JAK2/RIPK2/FGR/MELK/ZAP70/TXK/SYK/TEC/FRK/BTK/FER/LYN/SLA/HCK/TYK2	18
MF	GO:0019838	growth factor binding	36/2095	137/17697	2.598e-06	0.000284	0.0002546	CXCL13/IL2RG/IGFBP5/RHBDF2/IL2RB/IL11RA/LTBP3/NTRK2/IGFBP6/HTRA1/KAZALD1/LTBP2/BMPR1A/CD36/TWSG1/EGFR/TGFBR3/GHR/ERBB2/S100A13/GLG1/PTN/RHBDF1/KL/IL6ST/ACVR1/IL10RA/TGFB3/LIFR/IL1RN/IGFBP2/KDR/LRRC32/IL2RA/ITGAV/IL1R1	36
MF	GO:0005126	cytokine receptor binding	61/2095	286/17697	3.072e-06	0.0003052	0.0002737	CCL5/CXCL13/TRAF3/CXCL9/KITLG/XCL1/PIK3R1/CRLF1/CCR2/GDF5/BMP4/STAT1/TRAF1/CCL19/IL15/MYD88/INHBA/CCL13/BID/TNFSF10/LTB/CXCL1/JAK2/CXCL10/TGFBR3/CXCL8/CCL21/SOCS2/CD40LG/TLR5/CCL18/EFNA5/SMAD3/CXCL3/IL6ST/IFNG/CXCL11/PRL/CCL7/SYK/TRIP6/CTF1/TGFB3/IL6/CXCL2/LIFR/CXCL5/CXCL6/IL18/VEGFB/IL1RN/SH2B3/CFLAR/CCL17/CCL2/CCRL2/CCL23/IFNA1/TYK2/IL1B/CDH5	61
MF	GO:0008201	heparin binding	41/2095	169/17697	4.912e-06	0.0004474	0.0004011	PRELP/CXCL13/PLA2G2D/NELL1/NDNF/SFRP1/PTPRC/BMP4/SERPINA5/PCOLCE2/FGF7/ECM2/SELL/LTBP2/COMP/CXCL10/HBEGF/FGF2/TGFBR3/THBS4/ZNF207/PTPRF/PTN/PCOLCE/PTPRS/LRPAP1/HSD17B12/NELL2/LIPG/NAV2/CXCL11/CCL7/LXN/FGF9/ANXA4/CXCL6/APLP2/VEGFB/ANG/LIPC/CCL23	41
MF	GO:0033218	amide binding	71/2095	356/17697	6.27e-06	0.0005271	0.0004726	PIK3R1/TAP1/TAPBP/CLU/HLA-F/LILRB2/HLA-A/HLA-C/INHBA/PPP3CA/ACADVL/TLR2/CD74/GSTM3/ALDH6A1/ITGB2/NPR2/HLA-G/NOD2/CRYAB/CD36/PGRMC1/ERAP2/HLA-E/PC/HLA-DRA/MCCC1/LANCL1/HLA-DPB1/HLA-B/GHR/NLGN1/CLSTN1/NFKBIA/TMEM158/ACACB/SLC7A5/FZD4/LRPAP1/PCCA/KDELR3/SSTR5/NKTR/ECI2/HSP90AB1/ACVR1/EDNRB/TRHDE/PPIC/PEX19/KDELR2/HCRTR1/BACE1/ANPEP/HLA-DPA1/TYMS/KPNA2/FPR2/FOLH1/PPIG/ANG/CLIP3/TM2D1/ACADL/NPR3/GSTM2/PTH1R/VIPR1/TLR6/SOAT2/HADHA	71
MF	GO:0005178	integrin binding	34/2095	132/17697	7.821e-06	0.0005739	0.0005146	LCP1/IGF1/ITGB7/JAM3/EMP2/PTPN2/ITGB1BP1/ITGB2/ECM2/ICAM1/TIMP2/COMP/EGFR/FBLN5/ITGBL1/FGF2/THBS4/CD226/EDIL3/PTN/ICAM3/ADAM22/CD9/SYK/ITGB1BP2/ADAM10/LYN/ADAM23/KDR/CD81/ITGAV/ISG15/COL16A1/IL1B	34
MF	GO:0001618	virus receptor activity	23/2095	74/17697	8.518e-06	0.0005739	0.0005146	CCR5/SLAMF1/ITGB7/CXCR4/AXL/ICAM1/TNFRSF14/TFRC/EGFR/DAG1/NPC1/CR1/CDK1/CD86/HTR2A/CD80/TNFRSF4/SCARB2/ANPEP/SELPLG/CD81/ITGAV/CR2	23
MF	GO:0104005	hijacked molecular function	23/2095	74/17697	8.518e-06	0.0005739	0.0005146	CCR5/SLAMF1/ITGB7/CXCR4/AXL/ICAM1/TNFRSF14/TFRC/EGFR/DAG1/NPC1/CR1/CDK1/CD86/HTR2A/CD80/TNFRSF4/SCARB2/ANPEP/SELPLG/CD81/ITGAV/CR2	23
MF	GO:0044389	ubiquitin-like protein ligase binding	63/2095	308/17697	8.926e-06	0.0005739	0.0005146	TRAF3/UCHL1/CLU/GABARAPL1/TNFRSF1B/STAT1/TRAF1/CXCR4/SKI/UBXN7/BID/UBE2L6/UBE2C/NDUFS2/CBS/DIO2/SMC6/CD40/TNFRSF14/SNCAIP/EGFR/UBE2B/GABARAPL2/CASP10/SPOP/BAG2/ERLIN1/NFKBIA/DDX58/FZD4/FOXO1/SMAD3/MFHAS1/UBE2D1/VCP/CCNB1/HSP90AB1/PRDX6/ERLIN2/IKBKG/PINK1/FZD6/PTPN22/CUL2/PER3/NLK/UBE2J1/RB1/SLC25A5/LYN/CUL4B/HSPA1L/BAG5/NAE1/HLTF/PRR5L/ABI2/TP53/USP7/CAMLG/AURKA/MOAP1/PML	63
MF	GO:0031625	ubiquitin protein ligase binding	60/2095	290/17697	1.003e-05	0.0006088	0.0005459	TRAF3/UCHL1/CLU/GABARAPL1/TNFRSF1B/TRAF1/CXCR4/SKI/UBXN7/BID/UBE2L6/NDUFS2/CBS/DIO2/SMC6/CD40/TNFRSF14/SNCAIP/EGFR/UBE2B/GABARAPL2/CASP10/SPOP/BAG2/ERLIN1/NFKBIA/DDX58/FZD4/FOXO1/SMAD3/MFHAS1/UBE2D1/VCP/HSP90AB1/PRDX6/ERLIN2/IKBKG/PINK1/FZD6/PTPN22/CUL2/PER3/NLK/UBE2J1/RB1/SLC25A5/LYN/CUL4B/HSPA1L/BAG5/NAE1/HLTF/PRR5L/ABI2/TP53/USP7/CAMLG/AURKA/MOAP1/PML	60
MF	GO:0005070	SH3/SH2 adaptor activity	18/2095	52/17697	1.546e-05	0.0008896	0.0007976	SH2B2/LAT/SH2D2A/SH2D1A/SOCS2/SHB/SKAP1/PTPN11/CHN1/TOB1/SORBS1/ARHGAP4/SH2B3/SLA/TP53BP2/IRS4/KHDRBS1/VAV3	18
MF	GO:0015026	coreceptor activity	16/2095	44/17697	2.254e-05	0.001232	0.001105	CCR5/LRP6/CD8A/CXCR4/ITGA4/ACKR3/RECK/TGFBR3/CXCR6/LRP5/RYK/CD86/CD80/GPC4/CCR8/ITGAV	16
MF	GO:0004713	protein tyrosine kinase activity	33/2095	134/17697	2.874e-05	0.001496	0.001341	ITK/LCK/EPHA3/DDR2/CSK/NTRK2/AXL/NEK1/JAK2/RIPK2/FGR/EGFR/MELK/ZAP70/ERBB2/PDGFRL/TXK/EPHB1/EFEMP1/FLT3/SYK/TEC/FRK/BTK/TTK/FER/LYN/HIPK2/KDR/SLA/HCK/MERTK/TYK2	33
MF	GO:0019956	chemokine binding	13/2095	32/17697	3.386e-05	0.001609	0.001443	CCR5/CCR2/CXCR4/ITGA4/CCR7/ACKR3/PDPN/CCR1/CX3CR1/CXCR6/CCR8/ITGAV/CCRL2	13
MF	GO:0042277	peptide binding	59/2095	295/17697	3.387e-05	0.001609	0.001443	PIK3R1/TAP1/TAPBP/CLU/HLA-F/LILRB2/HLA-A/HLA-C/INHBA/PPP3CA/TLR2/CD74/GSTM3/ITGB2/NPR2/HLA-G/NOD2/CRYAB/CD36/PGRMC1/ERAP2/HLA-E/HLA-DRA/LANCL1/HLA-DPB1/HLA-B/GHR/NLGN1/CLSTN1/NFKBIA/TMEM158/SLC7A5/FZD4/LRPAP1/KDELR3/SSTR5/NKTR/HSP90AB1/ACVR1/EDNRB/TRHDE/PPIC/PEX19/KDELR2/HCRTR1/BACE1/ANPEP/HLA-DPA1/KPNA2/FPR2/FOLH1/PPIG/ANG/TM2D1/NPR3/GSTM2/PTH1R/VIPR1/TLR6	59
MF	GO:0005518	collagen binding	20/2095	67/17697	6.181e-05	0.002815	0.002524	DDR2/SPOCK2/PCOLCE2/SPOCK1/ANTXR1/ECM2/COCH/COMP/CTSL/DCN/MRC2/COL14A1/LUM/PCOLCE/CTSB/SMAD3/HSD17B12/ITGA10/PAK1/MMP12	20
MF	GO:0003779	actin binding	78/2095	431/17697	8.042e-05	0.003516	0.003153	LCP1/CCR5/WASF3/GBP1/EPB41L2/LIMCH1/CORO1A/ADD3/MYH10/PDLIM4/CXCR4/TMOD1/ANTXR1/COTL1/HCLS1/PFN2/MSRB2/MYO1F/FERMT2/NOD2/COBL/WASL/PSTPIP2/TMSB10/EGFR/TNS1/DAG1/CALD1/PHACTR2/WAS/ENAH/GAS7/PDLIM5/GMFG/CAP2/TAGLN/PARVA/MARCKSL1/PLS3/VPS16/DSTN/VASP/DIXDC1/ARPC5L/CORO2B/DAAM2/ABLIM1/LMOD1/PDLIM1/MICAL1/PKNOX2/MYO1C/SORBS1/CTTN/COBLL1/MAP1B/SSH3/CFL1/MYH11/CAPZA1/VILL/FERMT1/ANG/PANX1/ARPC1A/MYO3A/MYLK/WASF2/WDR1/ACTR3/KLHL4/PFN1/SNTA1/IQGAP2/SPTBN1/INF2/GSN/ACTR2	78
MF	GO:0035591	signaling adaptor activity	22/2095	80/17697	0.0001064	0.004474	0.004012	PIK3R1/SH2B2/TRAT1/LAT/SH2D2A/SH2D1A/SOCS2/SHB/SKAP1/PTPN11/CHN1/TOB1/SORBS1/AKAP13/ARHGAP4/GAB2/SH2B3/SLA/TP53BP2/IRS4/KHDRBS1/VAV3	22
MF	GO:0042605	peptide antigen binding	12/2095	31/17697	0.0001185	0.004799	0.004303	TAP1/TAPBP/HLA-F/HLA-A/HLA-C/HLA-G/HLA-E/HLA-DRA/HLA-DPB1/HLA-B/SLC7A5/HLA-DPA1	12
MF	GO:0016493	C-C chemokine receptor activity	10/2095	23/17697	0.0001403	0.005478	0.004912	CCR5/CCR2/CXCR4/CCR7/ACKR3/CCR1/CX3CR1/CXCR6/CCR8/CCRL2	10
MF	GO:0005125	cytokine activity	45/2095	220/17697	0.0001616	0.00609	0.005461	CCL5/CXCL13/CXCL9/KITLG/XCL1/CRLF1/GDF5/BMP4/TNFRSF11B/IL32/CCL19/SECTM1/IL15/INHBA/CCL13/TNFSF10/LTB/CXCL1/SCG2/CXCL10/FGF2/CXCL8/CCL21/CD40LG/FAM3C/CCL18/CXCL3/IL16/IFNG/CXCL11/CCL7/ADIPOQ/CTF1/TGFB3/IL6/CXCL2/CXCL5/CXCL6/IL18/IL1RN/CCL17/CCL2/CCL23/IFNA1/IL1B	45
MF	GO:0017147	Wnt-protein binding	13/2095	37/17697	0.0001963	0.007153	0.006413	SFRP1/LRP6/AXL/WLS/RECK/LRP5/RYK/FZD4/FZD7/FZD6/MERTK/FZD2/WIF1	13
MF	GO:0023026	MHC class II protein complex binding	8/2095	16/17697	0.0002032	0.007164	0.006423	CD74/HLA-DRA/HLA-DMA/MS4A1/ATP1B1/HLA-DMB/HSP90AB1/CD81	8
MF	GO:0019957	C-C chemokine binding	10/2095	24/17697	0.0002152	0.007349	0.006589	CCR5/CCR2/CXCR4/CCR7/ACKR3/CCR1/CX3CR1/CXCR6/CCR8/CCRL2	10
MF	GO:0016504	peptidase activator activity	13/2095	38/17697	0.0002663	0.008822	0.00791	PCOLCE2/CTSC/PSME1/PCOLCE/CASP1/ADRM1/VCP/PINK1/APAF1/FBLN1/NOD1/CFLAR/CTSH	13
MF	GO:0048020	CCR chemokine receptor binding	14/2095	43/17697	0.0002822	0.009073	0.008135	CCL5/CXCL13/XCL1/CCR2/STAT1/CCL19/CCL13/CCL21/CCL18/CCL7/CCL17/CCL2/CCRL2/CCL23	14
MF	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	15/2095	49/17697	0.0003694	0.01153	0.01034	CDKN2C/CDKN1C/CCND2/CCNB2/CCNT1/CCNA2/CKS2/HEXIM1/CCNI/CCNB1/CCND1/CKS1B/CCNG1/CCNF/CCNE2	15
MF	GO:0015631	tubulin binding	61/2095	336/17697	0.0004214	0.01279	0.01147	S100A9/EML4/GABARAPL1/NDN/CETN2/TPPP3/NUSAP1/MAPRE2/MX2/MAP4/EML1/RABGAP1/CRYAB/DYSF/GOLGA2/PLK1/DNM1/GABARAPL2/KIF11/DAG1/KIF15/KIF18B/KIF3B/FGF13/TPR/KIF21B/MAP9/GPAA1/ZNF207/HOOK2/KIF2C/KIF4A/DYNC1I1/MAP7D3/UNC5C/PRC1/CCDC88C/SKAP1/KIF20A/DIXDC1/RACGAP1/FEZ1/KIF16B/CETN3/TERF1/CAMSAP2/BEX4/MAP1B/SYBU/DPYSL2/MTUS1/CLIP3/LYN/VBP1/ARL4C/KIF20B/MX1/ARL3/KIFC1/KIF1B/KIF23	61
MF	GO:0001637	G protein-coupled chemoattractant receptor activity	10/2095	26/17697	0.0004663	0.01289	0.01155	CCR5/CCR2/CXCR4/CCR7/ACKR3/CCR1/CX3CR1/CXCR6/CCR8/CCRL2	10
MF	GO:0004950	chemokine receptor activity	10/2095	26/17697	0.0004663	0.01289	0.01155	CCR5/CCR2/CXCR4/CCR7/ACKR3/CCR1/CX3CR1/CXCR6/CCR8/CCRL2	10
MF	GO:0001784	phosphotyrosine residue binding	13/2095	40/17697	0.0004716	0.01289	0.01155	LCK/PIK3R1/SAMSN1/FGR/PTPN6/ZAP70/PLCG2/SHB/PTPN11/VAV1/SYK/PIK3R3/HCK	13
MF	GO:0042287	MHC protein binding	13/2095	40/17697	0.0004716	0.01289	0.01155	TAP1/TAPBP/CD8A/LILRB2/TAP2/CD74/HLA-E/CLEC7A/KLRD1/VCP/FAM49B/CD81/LILRB1	13
MF	GO:0070064	proline-rich region binding	8/2095	18/17697	0.0005552	0.0148	0.01327	CSK/ITSN1/WBP4/YAP1/GHR/CCND1/ABI2/PFN1	8
MF	GO:0008017	microtubule binding	47/2095	246/17697	0.0005958	0.0155	0.0139	S100A9/EML4/CETN2/NUSAP1/MAPRE2/MX2/MAP4/EML1/CRYAB/DYSF/GOLGA2/PLK1/DNM1/GABARAPL2/KIF11/KIF15/KIF18B/KIF3B/FGF13/KIF21B/MAP9/ZNF207/HOOK2/KIF2C/KIF4A/DYNC1I1/MAP7D3/PRC1/CCDC88C/SKAP1/KIF20A/RACGAP1/KIF16B/CETN3/TERF1/CAMSAP2/MAP1B/SYBU/DPYSL2/MTUS1/CLIP3/KIF20B/MX1/ARL3/KIFC1/KIF1B/KIF23	47
MF	GO:0019207	kinase regulator activity	41/2095	207/17697	0.000615	0.01563	0.01402	CCL5/CDKN2C/PIK3R1/LRP6/CDKN1C/RAC2/CCND2/SH3BP5/CCNB2/MALT1/ITSN1/SOCS1/CXCL10/CISH/GPRC5A/FGF13/CCNT1/RHOH/CCNA2/SOCS2/NCKAP1L/GMFG/TOM1L1/EFNA5/CKS2/HEXIM1/CCNI/CCNB1/SOCS6/PIK3CA/HSP90AB1/CCND1/MBIP/DBF4/CKS1B/HSPB1/PIK3R3/TESC/CCNG1/CCNF/CCNE2	41
MF	GO:0001664	G protein-coupled receptor binding	52/2095	280/17697	0.0006311	0.01568	0.01406	CCL5/CXCL13/CXCL9/XCL1/SFRP1/CCR2/UCHL1/LRP6/RTP4/PENK/WNT5B/GNAL/STAT1/FCN1/CCL19/CCL13/WLS/CXCL1/JAK2/CXCL10/DNM1/PDYN/TAC1/CXCL8/CCL21/NMB/MAGI2/RYK/CCL18/SNX5/ARHGEF12/PTPN11/FZD7/MYOC/CXCL3/FPR1/AGTR1/CXCL11/CCL7/BBS1/EDNRB/TULP3/CXCL2/CXCL5/CXCL6/DVL1/CCL17/S1PR1/CCL2/CCRL2/CCL23/TYK2	52
MF	GO:0001968	fibronectin binding	10/2095	27/17697	0.0006625	0.01609	0.01443	IGFBP5/ITGA4/IGFBP6/CTSL/HSD17B12/MYOC/PLEKHA2/FBLN1/FSTL3/ITGAV	10
MF	GO:0048018	receptor ligand activity	81/2095	482/17697	0.0006819	0.0162	0.01453	CCL5/CXCL13/CXCL9/KITLG/XCL1/CRLF1/GDF5/BMP4/TYMP/TNFRSF11B/IGF1/SEMA4A/PENK/BTC/IL32/PTHLH/FGF18/CCL19/SECTM1/IL15/OGN/SEMA4D/SEMA3A/INHBA/CCL13/FGF7/TNFSF10/LTB/CXCL1/PDGFD/SCG2/CXCL10/HBEGF/FGF2/THBS4/PDYN/CXCL8/FGF13/CCL21/NMB/HGF/CD40LG/PTN/GMFG/EFEMP1/FAM3C/CCL18/SEMA3F/EFNA5/KL/CXCL3/LEP/NBL1/IL16/IFNG/CXCL11/PRL/FGF14/CCL7/ADIPOQ/FGF9/CTF1/TGFB3/IL6/CXCL2/CD320/SEMA4F/CXCL5/CXCL6/IL18/SEMA3E/VEGFB/IL1RN/ENDOU/MIA/CCL17/SEMA6B/CCL2/CCL23/IFNA1/IL1B	81
MF	GO:0042393	histone binding	39/2095	197/17697	0.0008316	0.01934	0.01734	NAP1L2/STAT1/ING3/PRKCB/CHD1/NCAPD2/VRK1/JAK2/CTSL/TRIM24/USP3/KMT2A/TAF7/HJURP/LEF1/SMARCC2/SMARCA2/ATRX/ZMYND11/CKS2/BRD4/MCM2/MTF2/MSL3/NPM3/ASF1B/MPHOSPH8/KAT6B/CKS1B/SUZ12/IPO7/PHF10/RSF1/KDM7A/CHAF1B/EZH1/TBL1X/DNAJC2/SPIN1	39
MF	GO:0008013	beta-catenin binding	20/2095	82/17697	0.001158	0.02636	0.02364	DLG5/SOX9/GLI3/SKP1/CBY1/AR/TCF7/TCF7L2/CDH2/LEF1/FOXO1/SMAD3/KANK1/TCF7L1/DACT1/CALCOCO1/FOXO3/DVL1/TBL1X/CDH5	20
MF	GO:0050839	cell adhesion molecule binding	82/2095	499/17697	0.001248	0.02784	0.02497	LCP1/IGF1/MICALL1/ITGB7/LILRB2/STAT1/CDH19/ITGA4/JAM3/EMP2/PTPN2/CCNB2/ITGB1BP1/ITGB2/ECM2/EFHD2/PTPRD/ICAM1/ADAM8/GOLGA2/TIMP2/COMP/EGFR/FBLN5/GPRC5A/PTPN6/ITGBL1/FGF2/THBS4/CALD1/ITGAL/RPL24/GOLGA3/EIF3E/CD226/NLGN1/EDIL3/EHD4/PTPRF/PTN/PDLIM5/CDH2/PARVA/TMPO/ICAM3/SNX5/CPE/ADAM22/VASP/PTPN11/CD9/PPP1CA/PDLIM1/FNBP1L/HSP90AB1/PRDX6/SYK/ACVR1/ITGB1BP2/CTTN/COBLL1/HDLBP/CHMP2B/CAPZA1/ADAM10/DDX6/LYN/ADAM23/KDR/CD81/TENM4/WASF2/RPL15/ZC3HAV1/PFN1/ITGAV/CAMLG/ISG15/SPTBN1/COL16A1/IL1B/CDH5	82
MF	GO:0042288	MHC class I protein binding	8/2095	20/17697	0.001286	0.0281	0.0252	TAP1/TAPBP/CD8A/LILRB2/TAP2/HLA-E/VCP/LILRB1	8
MF	GO:0035325	Toll-like receptor binding	6/2095	12/17697	0.001338	0.02867	0.0257	S100A9/MYD88/TLR2/CD36/SYK/TLR6	6
MF	GO:0008191	metalloendopeptidase inhibitor activity	7/2095	16/17697	0.001396	0.02934	0.02631	TIMP3/SPOCK2/SPOCK1/TIMP4/TIMP2/RECK/LXN	7
MF	GO:0035326	enhancer binding	28/2095	133/17697	0.001654	0.03411	0.03058	RELB/FLI1/SOX9/ZBTB16/PBX3/NFE2L1/HOXC6/SPIB/IRF7/GATA2/KMT2A/HOXC4/NFKB1/BACH1/ZNF322/LEF1/SMAD3/SMARCC2/BHLHE41/ARNTL/ARNT/NFYA/CHD4/SPI1/CALCOCO1/HMGA1/TP53/HOXA5	28
MF	GO:0019903	protein phosphatase binding	29/2095	140/17697	0.001792	0.03628	0.03253	TRAF3/LCK/PIK3R1/PPP1R3C/CSK/LILRB2/STAT1/PDLIM4/PARD3/EGFR/SPHK1/ERBB2/CDH2/SOD1/NEK2/SKAP1/FOXO1/MFHAS1/FBXL2/VCP/GTF2F1/PPP1CA/FER/ENSA/PPP1R11/TP53/MVP/CDH5/LILRB1	29
MF	GO:0061134	peptidase regulator activity	41/2095	219/17697	0.001914	0.03804	0.0341	SERPINA1/TNFAIP8/BIRC3/TIMP3/SPOCK2/CST7/SERPINA3/SERPINA5/SLPI/PTTG1/PCOLCE2/SPOCK1/TIMP4/CTSC/TIMP2/PSME1/RPS6KA1/RECK/PROS1/UBE2Z/SPINT2/ITIH5/CD27/PCOLCE/PEBP1/CASP1/LEF1/ADRM1/VCP/SERPINI1/LXN/SERPINB1/PINK1/APAF1/FBLN1/APLP2/TFPI/NOD1/CFLAR/SPINK5/CTSH	41
MF	GO:0035173	histone kinase activity	7/2095	17/17697	0.002132	0.04089	0.03666	PRKCB/VRK1/JAK2/CDK1/CCNB1/AURKB/AURKA	7
MF	GO:0042813	Wnt-activated receptor activity	7/2095	17/17697	0.002132	0.04089	0.03666	LRP6/LRP5/RYK/FZD4/FZD7/FZD6/FZD2	7
MF	GO:0030971	receptor tyrosine kinase binding	17/2095	69/17697	0.002344	0.04418	0.03961	CPNE3/PIK3R1/CD2/PTPN14/SH2B2/TRAT1/ANGPT1/PTPN2/ZPR1/PTPN11/MYOC/TOB1/ITGAX/GAB2/SH2B3/SHC2/TP53	17
MF	GO:1990782	protein tyrosine kinase binding	21/2095	93/17697	0.00248	0.04577	0.04104	CPNE3/PIK3R1/CD2/PTPN14/CD247/SH2B2/TRAT1/ANGPT1/PTPN2/NOX4/ZPR1/PTPN11/MYOC/TOB1/ACVR1/ITGAX/GAB2/SH2B3/SHC2/TP53/CDH5	21
MF	GO:0004674	protein serine/threonine kinase activity	72/2095	439/17697	0.002513	0.04577	0.04104	CPNE3/STK10/CAB39L/PRKCH/PRKCQ/GRK6/PIM1/VRK2/BUB1/PRKCB/GAK/MAP3K11/VRK1/LIMK2/NEK1/BMPR1A/PLK1/PRKD2/MAP3K8/RIPK2/RPS6KA1/EGFR/STK32B/STK17B/MELK/TGFBR3/CDC42BPA/SRPK1/MAP4K1/PASK/PHKB/CDK1/SIK1/BUB1B/CAMK1D/NEK7/MAPK13/NEK2/RPS6KA4/CDK14/PLK2/BRD4/MAP3K2/CDC7/PIK3CA/MOK/PAK1/SYK/ACVR1/PINK1/AKT3/MAPKAPK2/MARK1/AKAP13/TTK/PRKG1/NLK/AURKB/BMP2K/PRKD1/HIPK2/MYO3A/MYLK/PBK/PRKAB1/PIM2/AURKA/CASK/TRPM6/ALPK3/DCLK1/PRKG2	72
MF	GO:0050431	transforming growth factor beta binding	8/2095	22/17697	0.002627	0.04707	0.0422	LTBP3/CD36/TWSG1/TGFBR3/ACVR1/TGFB3/LRRC32/ITGAV	8
MF	GO:0004725	protein tyrosine phosphatase activity	22/2095	100/17697	0.002804	0.04944	0.04433	PTPRC/PTPN14/EYA4/PTPRE/DUSP5/PTPN2/EYA2/PTPRD/PTPN7/CDC14B/PTPN6/CDC25B/MTMR14/PTPRF/PTPRS/PTPN11/PTPN13/PTPN22/DUSP6/SSH3/DUSP2/MTMR2	22
MF	GO:0051015	actin filament binding	37/2095	198/17697	0.003189	0.05533	0.04961	LCP1/CORO1A/ADD3/MYH10/TMOD1/ANTXR1/COTL1/HCLS1/FERMT2/WASL/PSTPIP2/EGFR/WAS/GAS7/TAGLN/PLS3/VPS16/DSTN/ARPC5L/CORO2B/ABLIM1/MICAL1/PKNOX2/MYO1C/CTTN/CFL1/MYH11/CAPZA1/VILL/FERMT1/PANX1/ARPC1A/WDR1/ACTR3/IQGAP2/GSN/ACTR2	37
MF	GO:0019902	phosphatase binding	35/2095	185/17697	0.003293	0.05624	0.05042	TRAF3/LCK/PIK3R1/PVRIG/PPP1R3C/CSK/LILRB2/STAT1/PDLIM4/PARD3/CTSC/EGFR/SPHK1/SH3YL1/ERBB2/MAGI2/CDH2/SOD1/NEK2/SKAP1/FOXO1/SMAD3/MFHAS1/FBXL2/VCP/GTF2F1/PPP1CA/SYK/FER/ENSA/PPP1R11/TP53/MVP/CDH5/LILRB1	35
MF	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity	6/2095	14/17697	0.003524	0.05926	0.05313	PIK3R1/SOCS1/CISH/SOCS2/SOCS6/PIK3R3	6
MF	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	71/2095	439/17697	0.003811	0.06312	0.05659	NFIC/BCL11B/IRF1/TFDP2/ZIC1/HLF/HOXC10/STAT1/HOXA10/NDN/FLI1/SOX9/PBX3/ELF4/BATF/GLI3/FOXC1/NUCKS1/RFX5/MEIS1/NFKB2/NFE2L1/IRF4/AR/SPIB/SIX1/SIX2/IRF2/GATA2/MEOX1/MEIS2/STAT4/TFEC/KLF7/ETV5/NFIB/CREB3L2/SP1/TXK/TBX21/SOX2/HOXC4/TP63/PITX1/PBX1/NFKB1/BACH1/MYBL1/LEF1/ETV6/SMAD3/NOTCH1/ARNTL/PAX5/TFAP2A/HOXA4/FOSL1/PARP1/HOXD10/SPI1/PLSCR1/DDIT3/FOXO3/CEBPA/HLTF/TP53/RFX4/FEZF2/EAF2/HOXA5/MYCL	71
MF	GO:0032934	sterol binding	14/2095	56/17697	0.004778	0.07795	0.06989	GPR183/ABCG1/NFE2L1/NPC1/ERLIN1/STARD5/ERLIN2/CETP/SCARB2/NR1H3/OSBPL1A/OSBPL9/CD81/SOAT2	14
MF	GO:0016805	dipeptidase activity	6/2095	15/17697	0.005291	0.08328	0.07467	SCRN3/CNDP2/NAALAD2/CPQ/SCRN1/FOLH1	6
MF	GO:0017048	Rho GTPase binding	33/2095	177/17697	0.005332	0.08328	0.07467	ARHGDIB/ARHGEF18/MAP3K11/ARHGEF9/ARHGEF26/ITSN1/KIF3B/ARHGAP17/WAS/CDC42EP3/RHOH/DOCK1/NCKAP1L/SOD1/ARHGEF3/ARHGEF10/ARHGEF12/NET1/DOCK2/VAV1/TNFAIP1/DAAM2/ECT2/PAK1/AKAP13/ARHGAP4/RALBP1/DVL1/ABI2/PFN1/IQGAP2/INF2/VAV3	33
MF	GO:0045309	protein phosphorylated amino acid binding	13/2095	51/17697	0.005395	0.08328	0.07467	LCK/PIK3R1/SAMSN1/FGR/PTPN6/ZAP70/PLCG2/SHB/PTPN11/VAV1/SYK/PIK3R3/HCK	13
MF	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	21/2095	99/17697	0.00541	0.08328	0.07467	RELB/FLI1/ZBTB16/PBX3/NFE2L1/HOXC6/SPIB/GATA2/KMT2A/HOXC4/NFKB1/BACH1/SMARCC2/BHLHE41/ARNTL/NFYA/CHD4/SPI1/CALCOCO1/TP53/HOXA5	21
MF	GO:0045236	CXCR chemokine receptor binding	5/2095	11/17697	0.005774	0.08765	0.07858	CXCL13/CXCL9/CXCL10/CXCL8/CXCL11	5
MF	GO:0001158	enhancer sequence-specific DNA binding	24/2095	119/17697	0.006028	0.09025	0.08092	RELB/FLI1/SOX9/ZBTB16/PBX3/NFE2L1/HOXC6/SPIB/IRF7/GATA2/KMT2A/HOXC4/NFKB1/BACH1/SMARCC2/BHLHE41/ARNTL/NFYA/CHD4/SPI1/CALCOCO1/HMGA1/TP53/HOXA5	24
MF	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	9/2095	30/17697	0.006298	0.09302	0.0834	PLEKHA1/SH3PXD2A/PLEK/PLEKHA4/KIF16B/PLEKHA2/GAB2/DAPP1/NCF1	9
MF	GO:0005496	steroid binding	20/2095	95/17697	0.007125	0.1038	0.0931	GPR183/ABCG1/NFE2L1/AR/PGRMC1/NPC1/ERLIN1/PGRMC2/KL/IRX5/STARD5/ATP1A2/ERLIN2/CETP/SCARB2/NR1H3/OSBPL1A/OSBPL9/CD81/SOAT2	20
MF	GO:0042169	SH2 domain binding	10/2095	36/17697	0.007386	0.1062	0.09523	LCK/JAK2/DAG1/PTPN6/DLC1/SKAP1/SYK/NLK/SHCBP1/LILRB1	10
MF	GO:0015923	mannosidase activity	6/2095	16/17697	0.007628	0.1083	0.09708	EDEM1/MAN1C1/MAN2B1/EDEM2/MAN2A2/MANBA	6
MF	GO:0004721	phosphoprotein phosphatase activity	33/2095	182/17697	0.008167	0.1144	0.1026	LCK/PTPRC/PPP1R3C/PTPN14/EYA4/PTPRE/PPP2CA/PPP3CA/DUSP5/PTPN2/EYA2/PTPRD/PTPN7/CDC14B/PTPN6/CDC25B/RPAP2/DLGAP5/MTMR14/PTPRF/PPP4C/PPP2CB/PTPRS/PTPN11/PTPN13/PPP1CA/PPM1F/PHLPP1/PTPN22/DUSP6/SSH3/DUSP2/MTMR2	33
MF	GO:0038187	pattern recognition receptor activity	7/2095	21/17697	0.00833	0.1152	0.1033	TLR8/FCN1/TLR2/CD36/CLEC7A/CLEC4E/COLEC12	7
MF	GO:0015485	cholesterol binding	12/2095	49/17697	0.01028	0.1385	0.1242	ABCG1/NFE2L1/NPC1/ERLIN1/STARD5/ERLIN2/CETP/SCARB2/NR1H3/OSBPL1A/CD81/SOAT2	12
MF	GO:0035014	phosphatidylinositol 3-kinase regulator activity	6/2095	17/17697	0.01063	0.1385	0.1242	PIK3R1/SOCS1/CISH/SOCS2/SOCS6/PIK3R3	6
MF	GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	6/2095	17/17697	0.01063	0.1385	0.1242	CYB5R4/NOX4/KMO/MICAL1/CYBA/NCF1	6
MF	GO:0004364	glutathione transferase activity	8/2095	27/17697	0.01064	0.1385	0.1242	LTC4S/GSTM5/GSTM3/GSTA4/LANCL1/HPGDS/GSTO1/GSTM2	8
MF	GO:0045499	chemorepellent activity	8/2095	27/17697	0.01064	0.1385	0.1242	SEMA4A/SEMA4D/SEMA3A/SEMA3F/EFNA5/SEMA4F/SEMA3E/SEMA6B	8
MF	GO:0005158	insulin receptor binding	7/2095	22/17697	0.01099	0.1397	0.1252	ENPP1/PIK3R1/IGF1/PTPN11/SORBS1/IRS4/LMBRD1	7
MF	GO:0030021	extracellular matrix structural constituent conferring compression resistance	7/2095	22/17697	0.01099	0.1397	0.1252	PRELP/FMOD/OGN/DCN/BGN/LUM/VCAN	7
MF	GO:0019887	protein kinase regulator activity	32/2095	180/17697	0.01206	0.1515	0.1358	CCL5/CDKN2C/CDKN1C/RAC2/CCND2/SH3BP5/CCNB2/SOCS1/CXCL10/GPRC5A/FGF13/CCNT1/CCNA2/NCKAP1L/GMFG/TOM1L1/EFNA5/CKS2/HEXIM1/CCNI/CCNB1/PIK3CA/HSP90AB1/CCND1/MBIP/DBF4/CKS1B/HSPB1/TESC/CCNG1/CCNF/CCNE2	32
MF	GO:0043621	protein self-association	13/2095	56/17697	0.01224	0.152	0.1363	CCL5/TNFAIP3/CD2/TMEM43/MYD88/MALT1/ADAM8/CTSC/CCDC88C/FLT3/VAMP2/PTH1R/TP53	13
MF	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	5/2095	13/17697	0.01313	0.1613	0.1446	PIK3R1/SH2B2/TRAT1/GAB2/SH2B3	5
MF	GO:0048365	Rac GTPase binding	15/2095	69/17697	0.01371	0.1664	0.1492	ARHGDIB/MAP3K11/ARHGAP17/WAS/NCKAP1L/SOD1/DOCK2/VAV1/PAK1/ARHGAP4/RALBP1/DVL1/ABI2/IQGAP2/VAV3	15
MF	GO:0070851	growth factor receptor binding	25/2095	134/17697	0.01385	0.1664	0.1492	BTC/FGF18/FGF7/JAK2/PDGFD/HBEGF/FGF2/TLR5/EFEMP1/MS4A1/KL/IL6ST/TRIP6/FGF9/IL6/FER/PLSCR1/VEGFB/IL1RN/LYN/ATXN2/IL1R1/VAV3/IL1B/CDH5	25
MF	GO:0005044	scavenger receptor activity	12/2095	51/17697	0.01417	0.1671	0.1498	ENPP1/SCARA3/CD5/ACKR3/CD36/SCARF1/CD6/COLEC12/CD163/SCARB2/ENDOU/STAB2	12
MF	GO:0030215	semaphorin receptor binding	7/2095	23/17697	0.01422	0.1671	0.1498	SEMA4A/SEMA4D/SEMA3A/SEMA3F/SEMA4F/SEMA3E/SEMA6B	7
MF	GO:0038191	neuropilin binding	6/2095	18/17697	0.01437	0.1671	0.1498	SEMA4A/SEMA4D/SEMA3A/SEMA3F/SEMA4F/SEMA3E	6
MF	GO:0051219	phosphoprotein binding	17/2095	83/17697	0.01626	0.1862	0.1669	LCK/PIK3R1/SAMSN1/FGR/PTPN6/ZAP70/PLCG2/SHB/PLAT/PTPN11/VAV1/SYK/PIK3R3/RB1/LYN/PKD2/HCK	17
MF	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	13/2095	58/17697	0.01635	0.1862	0.1669	LTC4S/GSTM5/GSTM3/GSTA4/CBS/LANCL1/HPGDS/MAT1A/NANS/HMBS/GSTO1/GSTM2/TRIT1	13
MF	GO:0003777	microtubule motor activity	17/2095	84/17697	0.01821	0.2052	0.1839	DYNC2LI1/DYNC1LI2/KIF11/KIF15/KIF18B/KIF3B/KIF21B/KIF2C/KIF4A/DYNC1I1/KIF20A/KIF16B/KIF20B/DYNLRB1/KIFC1/KIF1B/KIF23	17
MF	GO:0005507	copper ion binding	13/2095	59/17697	0.01877	0.2087	0.1872	SCO2/PAM/CP/F5/CUTC/S100A13/COX11/SOD1/PRND/AOC2/ANG/AOC3/TP53	13
MF	GO:0005080	protein kinase C binding	12/2095	53/17697	0.01908	0.2087	0.1872	NELL1/PRKCB/PRKD2/PLEK/PDLIM5/TOP2A/NELL2/FEZ1/DACT1/HSPB1/HINT1/ITGAV	12
MF	GO:0001540	amyloid-beta binding	16/2095	78/17697	0.0191	0.2087	0.1872	CLU/LILRB2/TLR2/CD74/ITGB2/CRYAB/CD36/PGRMC1/NLGN1/CLSTN1/FZD4/LRPAP1/BACE1/FPR2/TM2D1/TLR6	16
MF	GO:0005543	phospholipid binding	65/2095	427/17697	0.01973	0.2135	0.1914	PLA2G2D/PLEKHA1/CPNE3/PIGK/RASGRP1/BIN2/MICALL1/MREG/SERPINA5/DENND1C/PARD3/LPAR1/ABCG1/AXL/PFN2/FERMT2/DYSF/ANXA3/SNX7/SH3PXD2A/SH3YL1/PASK/IGHM/DENND1A/PLEK/GPAA1/AGAP1/PLD1/NCF4/LANCL2/PXDC1/KCNJ2/PLEKHA4/PEBP1/PLA2G4C/SNX5/CEACAM5/FZD7/RASA2/RACGAP1/KIF16B/DGKA/SYT17/TEC/PSD4/PLEKHA2/CETP/VAMP2/PITPNC1/BTK/TULP3/SCARB2/MARK1/MAP1B/ANXA4/OSBPL1A/GAB2/NME4/SNX10/DAPP1/NCF1/PFN1/IQGAP2/SPTBN1/PLA2G7	65
MF	GO:0008022	protein C-terminus binding	32/2095	187/17697	0.0203	0.214	0.1919	LCK/CORO1A/CSK/ZBTB16/SIPA1/PPP2CA/MKI67/PEX26/JAK2/MAD2L1/PRRC2C/YAP1/DNM1/FBLN5/ERBB2/SP1/CEP135/TOP2A/PPP2CB/ATP1B1/MYO1C/NIPBL/CALCOCO1/CENPF/FBLN1/CDC20/ERCC1/ATXN2/USP7/SH3GL3/TOPBP1/TBL1X	32
MF	GO:0038024	cargo receptor activity	17/2095	85/17697	0.02033	0.214	0.1919	ENPP1/LRP6/SCARA3/ITGB2/CD5/ACKR3/CD36/TFRC/SCARF1/CD6/COLEC12/CD163/LRP10/SCARB2/FPR2/ENDOU/STAB2	17
MF	GO:0043548	phosphatidylinositol 3-kinase binding	8/2095	30/17697	0.02037	0.214	0.1919	LCK/PIK3R1/CORO1A/AXL/JAK2/PTPN13/FBXL2/IRS4	8
MF	GO:0043394	proteoglycan binding	9/2095	36/17697	0.02165	0.2253	0.202	PLA2G2D/PTPRC/COMP/CTSL/PTPRF/PTN/PTPRS/CTSB/FST	9
MF	GO:0015924	mannosyl-oligosaccharide mannosidase activity	4/2095	10/17697	0.02283	0.231	0.2071	EDEM1/MAN1C1/EDEM2/MAN2A2	4
MF	GO:0016803	ether hydrolase activity	4/2095	10/17697	0.02283	0.231	0.2071	EPHX1/EPHX3/AKR7A2/EPHX2	4
MF	GO:0035374	chondroitin sulfate binding	4/2095	10/17697	0.02283	0.231	0.2071	PTN/PTPRS/DPYSL3/ANXA4	4
MF	GO:0008329	signaling pattern recognition receptor activity	6/2095	20/17697	0.02441	0.2379	0.2133	TLR8/FCN1/TLR2/CD36/CLEC7A/COLEC12	6
MF	GO:0043138	3'-5' DNA helicase activity	6/2095	20/17697	0.02441	0.2379	0.2133	CDC45/BLM/MCM5/GINS1/MCM2/ACTR8	6
MF	GO:0050699	WW domain binding	8/2095	31/17697	0.02468	0.2379	0.2133	TCEAL2/ENAH/TP63/PMEPA1/TCEAL4/TCEAL1/NDFIP1/KIF20B	8
MF	GO:0050662	coenzyme binding	46/2095	291/17697	0.02488	0.2379	0.2133	LBR/GCH1/FMO2/KYNU/ACADVL/ACOX2/SIRT7/ALDH6A1/NDUFS2/CRYZL1/CBS/PAM/SGPL1/OAT/CYB5R3/PC/SDR39U1/MCCC1/IDH2/ACAT1/NOX4/ACACB/CYB5R1/DUS1L/PGD/PCCA/UGDH/ALAS1/P4HTM/BDH2/KMO/ECI2/MICAL1/PARP1/NDUFA9/MDH1/MAOB/ACADL/SDHA/KCNAB1/CAT/HADH/PRMT1/SOAT2/GPD1L/HADHA	46
MF	GO:0001846	opsonin binding	5/2095	15/17697	0.02506	0.2379	0.2133	ITGB2/CR1/CD93/ITGAV/PTX3	5
MF	GO:0004559	alpha-mannosidase activity	5/2095	15/17697	0.02506	0.2379	0.2133	EDEM1/MAN1C1/MAN2B1/EDEM2/MAN2A2	5
MF	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process	5/2095	15/17697	0.02506	0.2379	0.2133	CASP10/CASP1/CASP5/CFLAR/CASP4	5
MF	GO:0016651	oxidoreductase activity, acting on NAD(P)H	20/2095	107/17697	0.02525	0.2379	0.2133	NQO1/NDUFC1/AKR1C3/NDUFS2/CRYZL1/NDUFS4/CYB5R3/AKR1C1/CYB5R4/NOX4/NDUFA13/CYB5R1/KMO/MICAL1/NDUFA9/ECSIT/CYBA/NDUFB6/NCF1/NDUFA4	20
MF	GO:0016791	phosphatase activity	43/2095	270/17697	0.02619	0.2446	0.2193	LCK/PTPRC/PPP1R3C/PTPN14/NT5E/EYA4/PTPRE/HDDC2/PPP2CA/PPP3CA/DUSP5/PTPN2/EYA2/PTPRD/PTPN7/CDC14B/PTPN6/CDC25B/RPAP2/DLGAP5/ACP2/MTMR14/PTPRF/PPP4C/PPP2CB/PTPRS/INPP1/PTPN11/PTPN13/PSPH/PPP1CA/PPM1F/ALPL/PHLPP1/PTPN22/DUSP6/INPP5D/SSH3/DUSP2/MTMR2/UBASH3A/EPHX2/BPNT1	43
MF	GO:0060589	nucleoside-triphosphatase regulator activity	53/2095	344/17697	0.02668	0.2471	0.2216	ARHGDIB/FAM13A/ARHGAP25/SIPA1/RALGDS/TBC1D16/RASGRP3/TBC1D5/ITGB1BP1/RABGAP1/ACAP1/WASL/HTR2B/GPSM3/TBC1D9/DLC1/NCAPH/STARD8/ARHGAP17/WAS/TBC1D8B/BAG2/AGAP1/RHOH/ARHGAP22/PLN/ASAP2/DOCK1/NCKAP1L/TBC1D1/RABGAP1L/GMIP/ATP1B1/ARHGEF12/DOCK2/RASA2/CHN1/TOR1AIP1/RACGAP1/ECT2/GDI1/DEPDC1/ARHGAP4/IPO7/RALBP1/RGS1/DNAJB4/NUP50/PFN1/SEC23B/IQGAP2/VAV3/ARHGAP12	53
MF	GO:0030674	protein binding, bridging	29/2095	170/17697	0.02716	0.2479	0.2223	PIK3R1/SH2B2/TRAT1/LAT/ANK2/SH2D2A/COL8A2/SH2D1A/COL14A1/SORBS2/SOCS2/SHB/SKAP1/PTPN11/CHN1/TOB1/SERINC1/SORBS1/TRIM22/ARHGAP4/GAB2/SH2B3/SLA/TP53BP2/IRS4/ABI2/KHDRBS1/VAV3/ST13	29
MF	GO:0008083	growth factor activity	28/2095	163/17697	0.02722	0.2479	0.2223	KITLG/GDF5/BMP4/TYMP/IGF1/BTC/FGF18/OGN/INHBA/FGF7/CXCL1/PDGFD/HBEGF/FGF2/THBS4/FGF13/HGF/PTN/GMFG/EFEMP1/FGF14/FGF9/TGFB3/IL6/CD320/VEGFB/ENDOU/MIA	28
MF	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed	7/2095	26/17697	0.02785	0.2516	0.2255	KIF11/KIF18B/KIF3B/DYNC1I1/KIF16B/KIF20B/KIF1B	7
MF	GO:0003725	double-stranded RNA binding	15/2095	75/17697	0.02815	0.2522	0.2261	TLR8/RFTN1/OAS2/OAS1/IFIH1/TFRC/OASL/DDX58/DDX60/ADAR/HSP90AB1/EIF4B/DDX1/OAS3/YRDC	15
MF	GO:0001848	complement binding	6/2095	21/17697	0.03085	0.2711	0.2431	ITGB2/CR1/CD93/CFB/CR2/PTX3	6
MF	GO:0051861	glycolipid binding	6/2095	21/17697	0.03085	0.2711	0.2431	PIGK/SELL/GPAA1/CEACAM5/CLIP3/LYN	6
MF	GO:0016801	hydrolase activity, acting on ether bonds	4/2095	11/17697	0.03257	0.2711	0.2431	EPHX1/EPHX3/AKR7A2/EPHX2	4
MF	GO:0043560	insulin receptor substrate binding	4/2095	11/17697	0.03257	0.2711	0.2431	PIK3R1/JAK2/PTPN11/PIK3CA	4
MF	GO:0004697	protein kinase C activity	5/2095	16/17697	0.03299	0.2711	0.2431	PRKCH/PRKCQ/PRKCB/PRKD2/PRKD1	5
MF	GO:0005159	insulin-like growth factor receptor binding	5/2095	16/17697	0.03299	0.2711	0.2431	PIK3R1/IGF1/SOCS1/SOCS2/REN	5
MF	GO:0005521	lamin binding	5/2095	16/17697	0.03299	0.2711	0.2431	LBR/IFI27/TMPO/TOR1AIP1/BNIP3L	5
MF	GO:0030169	low-density lipoprotein particle binding	5/2095	16/17697	0.03299	0.2711	0.2431	CD36/SCARF1/COLEC12/LIPC/STAB2	5
MF	GO:0043274	phospholipase binding	5/2095	16/17697	0.03299	0.2711	0.2431	LMNB1/SELE/WAS/PTPN11/STXBP1	5
MF	GO:0043395	heparan sulfate proteoglycan binding	5/2095	16/17697	0.03299	0.2711	0.2431	PLA2G2D/PTPRC/COMP/PTPRS/FST	5
MF	GO:0050700	CARD domain binding	5/2095	16/17697	0.03299	0.2711	0.2431	NOD2/RIPK2/CASP1/NOD1/CASP4	5
MF	GO:0001653	peptide receptor activity	26/2095	152/17697	0.03394	0.2769	0.2482	CCR5/CCR2/CXCR4/NPY1R/CCR7/SIGMAR1/NPR2/ACKR3/CCR1/CX3CR1/CXCR6/OGFRL1/NPY6R/FPR1/SSTR5/AGTR1/APLNR/EDNRB/HCRTR1/CCR8/FPR2/GP1BA/NPR3/PTH1R/VIPR1/CCRL2	26
MF	GO:0033293	monocarboxylic acid binding	13/2095	64/17697	0.03502	0.2825	0.2533	S100A9/SERPINA5/ACOX2/AKR1C1/PC/MCCC1/ID3/ACACB/PCCA/STARD5/FABP5/ADH5/FABP4	13
MF	GO:0005154	epidermal growth factor receptor binding	8/2095	33/17697	0.03515	0.2825	0.2533	BTC/HBEGF/EFEMP1/MS4A1/FER/PLSCR1/ATXN2/VAV3	8
MF	GO:0008528	G protein-coupled peptide receptor activity	25/2095	146/17697	0.03659	0.2919	0.2617	CCR5/CCR2/CXCR4/NPY1R/CCR7/SIGMAR1/ACKR3/CCR1/CX3CR1/CXCR6/OGFRL1/NPY6R/FPR1/SSTR5/AGTR1/APLNR/EDNRB/HCRTR1/CCR8/FPR2/GP1BA/NPR3/PTH1R/VIPR1/CCRL2	25
MF	GO:0061135	endopeptidase regulator activity	30/2095	182/17697	0.03772	0.2988	0.2679	SERPINA1/TNFAIP8/BIRC3/TIMP3/SPOCK2/CST7/SERPINA3/SERPINA5/SLPI/PTTG1/SPOCK1/TIMP4/TIMP2/PSME1/RPS6KA1/RECK/PROS1/UBE2Z/SPINT2/ITIH5/CD27/PEBP1/LEF1/ADRM1/SERPINI1/LXN/SERPINB1/APLP2/TFPI/SPINK5	30
MF	GO:0000062	fatty-acyl-CoA binding	6/2095	22/17697	0.0383	0.3011	0.27	ACADVL/ALDH6A1/ECI2/ACADL/SOAT2/HADHA	6
MF	GO:0042578	phosphoric ester hydrolase activity	55/2095	367/17697	0.03875	0.3026	0.2713	CCL5/ENPP1/CCR5/LCK/PTPRC/MPPED2/PPP1R3C/PTPN14/NT5E/EYA4/PLCE1/PTPRE/HDDC2/PPP2CA/PPP3CA/DUSP5/PTPN2/EYA2/PTPRD/PTPN7/CDC14B/PTPN6/CDC25B/PDE1A/RPAP2/PLCG2/DLGAP5/ACP2/CCR1/PLD1/MTMR14/PTPRF/PPP4C/PPP2CB/PTPRS/INPP1/PTPN11/PTPN13/TDP1/PSPH/PPP1CA/PPM1F/ALPL/PHLPP1/PTPN22/DUSP6/INPP5D/SSH3/DUSP2/PDE3B/MTMR2/UBASH3A/GDPD5/EPHX2/BPNT1	55
MF	GO:0003785	actin monomer binding	7/2095	28/17697	0.0407	0.3103	0.2782	CORO1A/PFN2/COBL/TMSB10/PKNOX2/COBLL1/PFN1	7
MF	GO:0030507	spectrin binding	7/2095	28/17697	0.0407	0.3103	0.2782	PTPRC/GBP1/EPB41L2/ADD3/ANK2/DYNC1I1/CAMSAP2	7
MF	GO:1901567	fatty acid derivative binding	7/2095	28/17697	0.0407	0.3103	0.2782	S100A9/ACADVL/ALDH6A1/ECI2/ACADL/SOAT2/HADHA	7
MF	GO:0030246	carbohydrate binding	42/2095	271/17697	0.04088	0.3103	0.2782	ENPP1/LGALS2/SCARA3/GALNT11/KLRB1/CLEC10A/FCN1/CLEC1A/PAM/CD72/LGALS9/SELL/LY75/GALNT10/KLRF1/HK3/CLEC7A/HLA-DRA/SELE/MRC2/CD69/CLEC4E/CD93/KLRD1/RPIA/SLC2A3/VCAN/COLEC12/P4HTM/CLEC4A/CLEC2D/CHODL/UGP2/MAN2B1/ENDOU/CLEC2B/MAN2A2/MANBA/LGALSL/TALDO1/SLC2A5/PTX3	42
MF	GO:0001085	RNA polymerase II transcription factor binding	26/2095	155/17697	0.04188	0.3105	0.2784	HCLS1/AR/ZFPM2/HDAC4/ZNHIT6/CREBBP/IFI27/TAF7/SP1/TBX21/TCF7L2/ID3/PITX1/SMAD3/BHLHE41/HEY2/DACT1/BBS1/CHD4/GTF2A1/SPI1/RB1/HIPK2/ERCC1/TP53/TEAD4	26
MF	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	5/2095	17/17697	0.0423	0.3105	0.2784	PTPRC/PTPRE/PTPRD/PTPN6/PTPRF	5
MF	GO:0019198	transmembrane receptor protein phosphatase activity	5/2095	17/17697	0.0423	0.3105	0.2784	PTPRC/PTPRE/PTPRD/PTPN6/PTPRF	5
MF	GO:0042834	peptidoglycan binding	5/2095	17/17697	0.0423	0.3105	0.2784	TLR2/NOD2/IGHM/NOD1/NLRP3	5
MF	GO:0008238	exopeptidase activity	20/2095	113/17697	0.04236	0.3105	0.2784	LAP3/UCHL1/DPP3/PREPL/XPNPEP3/CPD/ERAP2/SCRN3/CNDP2/NAALAD2/CPE/CPQ/CPA3/TRHDE/BACE1/SCRN1/ANPEP/FOLH1/METAP2/CTSH	20
MF	GO:0019199	transmembrane receptor protein kinase activity	15/2095	79/17697	0.04261	0.3105	0.2784	EPHA3/DDR2/NTRK2/AXL/BMPR1A/EGFR/TGFBR3/ERBB2/PDGFRL/EPHB1/EFEMP1/FLT3/ACVR1/KDR/MERTK	15
MF	GO:0016209	antioxidant activity	16/2095	86/17697	0.04377	0.311	0.2789	S100A9/NQO1/LTC4S/HBB/SOD1/GPX3/IPCEF1/GPX4/HBD/PRDX6/PTGS1/HP/SESN1/GSTO1/CAT/GSTM2	16
MF	GO:0005201	extracellular matrix structural constituent	27/2095	163/17697	0.04437	0.311	0.2789	PRELP/FMOD/MGP/DPT/OGN/MFAP4/LAMA2/EFEMP2/CILP/LTBP2/COMP/FBLN5/COL8A2/DCN/BGN/SPON1/COL8A1/COL14A1/EDIL3/LUM/EFEMP1/PCOLCE/VCAN/COL15A1/ADIPOQ/FBLN1/COL16A1	27
MF	GO:0005041	low-density lipoprotein particle receptor activity	4/2095	12/17697	0.04439	0.311	0.2789	LRP6/CD36/LRP10/STAB2	4
MF	GO:0031994	insulin-like growth factor I binding	4/2095	12/17697	0.04439	0.311	0.2789	IGFBP5/IGFBP6/IGFBP2/ITGAV	4
MF	GO:0032036	myosin heavy chain binding	4/2095	12/17697	0.04439	0.311	0.2789	LIMCH1/CORO1A/AXL/MYL9	4
MF	GO:1900750	oligopeptide binding	4/2095	12/17697	0.04439	0.311	0.2789	GSTM3/LANCL1/FOLH1/GSTM2	4
MF	GO:0009055	electron transfer activity	20/2095	114/17697	0.04588	0.3176	0.2848	IDO1/NQO1/NDUFA4L2/NDUFS2/COX7A1/AKR1B1/DHRS3/ASPH/NOX4/COX11/ETFB/AOC2/MAOB/ADH5/CYBA/SDHA/NCF1/AKR7A2/NDUFA4/COX7A2	20
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	22/2095	128/17697	0.04591	0.3176	0.2848	ALDH3A2/AKR1C3/ADH1C/ABCC4/AKR1B1/DHRS3/AKR1C1/IDH2/VKORC1/PGD/HSD17B12/UGDH/BDH2/ADH1B/BDH1/MDH1/ADH5/DHRS9/KCNAB1/HADH/AKR7A2/HADHA	22
MF	GO:0017134	fibroblast growth factor binding	6/2095	23/17697	0.04679	0.3206	0.2875	CXCL13/TGFBR3/S100A13/GLG1/KL/ITGAV	6
MF	GO:0051117	ATPase binding	15/2095	80/17697	0.04693	0.3206	0.2875	LCK/ANK2/TCIRG1/AR/PEX26/GABARAPL2/ZNHIT6/PLN/ATP1B1/TOR1AIP1/PEX19/SDF2L1/SNX10/PKD2/SNTA1	15
MF	GO:0030695	GTPase regulator activity	46/2095	304/17697	0.04777	0.3243	0.2907	ARHGDIB/FAM13A/ARHGAP25/SIPA1/RALGDS/TBC1D16/RASGRP3/TBC1D5/ITGB1BP1/RABGAP1/ACAP1/WASL/HTR2B/GPSM3/TBC1D9/DLC1/STARD8/ARHGAP17/WAS/TBC1D8B/AGAP1/RHOH/ARHGAP22/ASAP2/DOCK1/NCKAP1L/TBC1D1/RABGAP1L/GMIP/ARHGEF12/DOCK2/RASA2/CHN1/RACGAP1/ECT2/GDI1/DEPDC1/ARHGAP4/IPO7/RALBP1/RGS1/NUP50/SEC23B/IQGAP2/VAV3/ARHGAP12	46
MF	GO:0003774	motor activity	23/2095	136/17697	0.04915	0.3316	0.2973	DYNC2LI1/MYH10/MYO1F/DYNC1LI2/KIF11/KIF15/KIF18B/KIF3B/KIF21B/KIF2C/KIF4A/DYNC1I1/KIF20A/KIF16B/MYO1C/MYH11/KIF20B/MYO3A/DYNLRB1/MYL6B/KIFC1/KIF1B/KIF23	23
MF	GO:1990841	promoter-specific chromatin binding	10/2095	48/17697	0.05163	0.3462	0.3104	STAT1/FOXC1/NFE2L1/HDAC4/USP3/EZH2/DNMT1/GTF2F1/SUZ12/TP53	10
MF	GO:0051087	chaperone binding	18/2095	102/17697	0.0534	0.3546	0.3179	CLU/GAK/CTSC/CP/PDPN/BAG2/BAK1/SOD1/ATP1A2/UBL4A/SCARB2/SDF2L1/CDC37L1/HSPB6/BAG5/DNAJB4/TP53/ST13	18
MF	GO:0004197	cysteine-type endopeptidase activity	20/2095	116/17697	0.05353	0.3546	0.3179	SFRP1/UCHL1/CTSF/USP11/USP46/MALT1/CTSC/CTSL/CTSW/CASP10/CTSO/CASP1/CTSB/CASP5/CFLAR/CAPN7/USP10/CASP4/USP7/CTSH	20
MF	GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	9/2095	42/17697	0.05398	0.3554	0.3187	TNFAIP8/BIRC3/RPS6KA1/CD27/CASP1/LEF1/APAF1/NOD1/CTSH	9
MF	GO:0017016	Ras GTPase binding	62/2095	429/17697	0.05542	0.3619	0.3245	RASGRP1/MICALL1/PLCE1/ARHGDIB/DENND1C/TBC1D16/SH3BP5/RAB8A/RASGRP3/ARHGEF18/RHOBTB3/TBC1D5/DMXL2/MAP3K11/ARHGEF9/RABGAP1/ARHGEF26/ITSN1/TBC1D9/XPO6/KIF3B/DENND1A/ARHGAP17/WAS/TBC1D8B/CDC42EP3/RHOH/DOCK1/NCKAP1L/SOD1/TBC1D1/ARHGEF3/ARHGEF10/RABGAP1L/ARHGEF12/NET1/DOCK2/VAV1/TNFAIP1/DAAM2/ECT2/KIF16B/GDI1/YIPF1/MICAL1/PAK1/MYO1C/AKAP13/ARHGAP4/DENND3/IPO7/RALBP1/DENND4B/DVL1/ABI2/RAB11FIP2/NUP50/PFN1/IQGAP2/INF2/VAV3/RAB11FIP1	62
MF	GO:0016887	ATPase activity	56/2095	384/17697	0.05744	0.3619	0.3245	TAP1/YME1L1/TAPBP/DYNC2LI1/MYH10/PCYOX1/TAP2/ABCG1/RHOBTB3/PFN2/TCIRG1/ABCC4/ATP8A1/KIF11/KIF15/BLM/KIF18B/HSPA6/SMARCA1/KIF3B/BPTF/KIF21B/MCM5/KIF2C/KIF4A/RFC3/DYNC1I1/TOP2A/ATP1B1/KIF20A/ABCA8/SMARCA2/ATRX/VCP/ATP13A3/KIF16B/MCM2/ATP1A2/HSP90AB1/MYO1C/DDX39A/CD320/RALBP1/ABCA3/ERCC6L/HSPA1L/KIF20B/MYO3A/SMCHD1/LMBRD1/ATP6V1B2/KIFC1/KIF1B/AK6/KIF23/ATP2A3	56
MF	GO:0004714	transmembrane receptor protein tyrosine kinase activity	12/2095	62/17697	0.05758	0.3619	0.3245	EPHA3/DDR2/NTRK2/AXL/EGFR/ERBB2/PDGFRL/EPHB1/EFEMP1/FLT3/KDR/MERTK	12
MF	GO:0017046	peptide hormone binding	10/2095	49/17697	0.05828	0.3619	0.3245	PIK3R1/INHBA/NPR2/GHR/ACVR1/EDNRB/HCRTR1/NPR3/PTH1R/VIPR1	10
MF	GO:0001608	G protein-coupled nucleotide receptor activity	4/2095	13/17697	0.05828	0.3619	0.3245	GPR171/P2RY6/P2RY14/P2RY4	4
MF	GO:0004032	alditol:NADP+ 1-oxidoreductase activity	4/2095	13/17697	0.05828	0.3619	0.3245	AKR1C3/AKR1B1/AKR1C1/AKR7A2	4
MF	GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	4/2095	13/17697	0.05828	0.3619	0.3245	NQO1/CYB5R3/CYB5R4/CYB5R1	4
MF	GO:0031404	chloride ion binding	4/2095	13/17697	0.05828	0.3619	0.3245	CLCN4/CTSC/NPR3/CLCN5	4
MF	GO:0039706	co-receptor binding	4/2095	13/17697	0.05828	0.3619	0.3245	BMP4/NEO1/HFE/DKK3	4
MF	GO:0045028	G protein-coupled purinergic nucleotide receptor activity	4/2095	13/17697	0.05828	0.3619	0.3245	GPR171/P2RY6/P2RY14/P2RY4	4
MF	GO:0004866	endopeptidase inhibitor activity	28/2095	175/17697	0.05972	0.3688	0.3306	SERPINA1/TNFAIP8/BIRC3/TIMP3/SPOCK2/CST7/SERPINA3/SERPINA5/SLPI/PTTG1/SPOCK1/TIMP4/TIMP2/RPS6KA1/RECK/PROS1/UBE2Z/SPINT2/ITIH5/CD27/PEBP1/LEF1/SERPINI1/LXN/SERPINB1/APLP2/TFPI/SPINK5	28
MF	GO:0043130	ubiquitin binding	14/2095	76/17697	0.0608	0.3733	0.3347	TNFAIP3/UCHL1/CXCR4/UBXN7/UBE2L6/TOP2A/TOM1L1/ADRM1/SMAD3/CKS2/IKBKG/CKS1B/HSPB1/RNF19B	14
MF	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	11/2095	56/17697	0.06147	0.3733	0.3347	LTC4S/HBB/GPX3/IPCEF1/GPX4/HBD/PRDX6/PTGS1/SESN1/CAT/GSTM2	11
MF	GO:0051287	NAD binding	11/2095	56/17697	0.06147	0.3733	0.3347	SIRT7/NDUFS2/CYB5R3/IDH2/UGDH/BDH2/PARP1/MDH1/HADH/GPD1L/HADHA	11
MF	GO:0042826	histone deacetylase binding	19/2095	111/17697	0.06237	0.3767	0.3377	HOXA10/GLI3/HDAC4/SP1/TOP2A/LEF1/BHLHE41/HEY2/HSP90AB1/DACT1/CCND1/CHD4/PARP1/BEX4/NIPBL/KPNA2/CDC20/TP53/NRIP1	19
MF	GO:0015144	carbohydrate transmembrane transporter activity	8/2095	37/17697	0.06418	0.3854	0.3456	SLC17A5/SLC2A6/AQP9/SLC2A3/SLC2A10/SLC5A3/SLC23A2/SLC2A5	8
MF	GO:0005402	carbohydrate:cation symporter activity	5/2095	19/17697	0.06523	0.3875	0.3474	SLC17A5/SLC2A6/SLC2A10/SLC5A3/SLC23A2	5
MF	GO:0016505	peptidase activator activity involved in apoptotic process	5/2095	19/17697	0.06523	0.3875	0.3474	CTSC/CASP1/APAF1/NOD1/CTSH	5
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	20/2095	119/17697	0.06664	0.3916	0.3511	AKR1C3/ADH1C/ABCC4/AKR1B1/DHRS3/AKR1C1/IDH2/PGD/HSD17B12/UGDH/BDH2/ADH1B/BDH1/MDH1/ADH5/DHRS9/KCNAB1/HADH/AKR7A2/HADHA	20
MF	GO:0031072	heat shock protein binding	20/2095	119/17697	0.06664	0.3916	0.3511	GBP1/ITGB2/NOD2/HSPA6/TPR/CDK1/BAG2/BAK1/ARNTL/FKBP5/HSP90AB1/DNAJC7/APAF1/TFAM/CDC37L1/KDR/HSPA1L/DNAJC2/ST13/METTL22	20
MF	GO:0019205	nucleobase-containing compound kinase activity	9/2095	44/17697	0.06943	0.4026	0.361	ADK/NME7/AK1/NME4/CLP1/TK2/TK1/CASK/AK6	9
MF	GO:0051427	hormone receptor binding	29/2095	185/17697	0.06955	0.4026	0.361	PTHLH/STAT1/PRKCB/JAK2/TRIM24/OASL/TAF7/TACC1/SMARCD3/TCF7L2/SOCS2/LEF1/SMAD3/PTPN11/TACC2/LEP/LRIF1/FLT3/TRIP6/PARP1/RB1/FABP4/HMGA1/MED14/TOB2/NRIP1/TYK2/MED13/RNF14	29
MF	GO:0004386	helicase activity	26/2095	163/17697	0.06962	0.4026	0.361	CHD1/IFIH1/CDC45/BLM/DDX24/SMARCA1/MCM5/RFC3/DDX58/GINS1/SMARCA2/ATRX/NAV2/DDX60/MCM2/DHX8/DDX1/CHD4/ACTR8/DDX39A/HELLS/DDX6/MCM4/ERCC6L/CHD9/HLTF	26
MF	GO:0017022	myosin binding	13/2095	71/17697	0.07183	0.4132	0.3705	LIMCH1/CORO1A/CXCR4/RAB8A/AXL/TRAK2/CALD1/LARP6/RAB27A/MYOC/MYL9/RAB14/GSN	13
MF	GO:0003714	transcription corepressor activity	36/2095	238/17697	0.07294	0.4138	0.371	RELB/ZHX3/RBFOX2/SKI/RUNX1T1/CBFA2T3/ZFPM2/HOXC6/HDAC4/YAP1/MEIS2/TFEC/CREBBP/E2F8/EZH2/ID3/SAP18/RCOR3/BHLHE41/ZMYND11/EID1/TOB1/MECP2/CCND1/TRIM22/WWTR1/ZHX2/DDIT3/HIPK2/PBXIP1/TOB2/EZH1/NRIP1/TBL1X/SSX1/SCAI	36
MF	GO:0042056	chemoattractant activity	8/2095	38/17697	0.07323	0.4138	0.371	CCL5/BMP4/FGF7/SCG2/CXCL10/FGF2/HGF/VEGFB	8
MF	GO:0061631	ubiquitin conjugating enzyme activity	8/2095	38/17697	0.07323	0.4138	0.371	UBE2L6/UBE2C/UBE2B/UBE2Z/UBE2D1/UBE2J1/UBE2E3/UBE2G2	8
MF	GO:0045125	bioactive lipid receptor activity	4/2095	14/17697	0.0742	0.4138	0.371	LPAR1/SPHK1/S1PR1/S1PR4	4
MF	GO:0045504	dynein heavy chain binding	4/2095	14/17697	0.0742	0.4138	0.371	DYNC2LI1/DYNC1LI2/DYNC1I1/TRIM58	4
MF	GO:0048185	activin binding	4/2095	14/17697	0.0742	0.4138	0.371	TGFBR3/ACVR1/FST/FSTL3	4
MF	GO:0042623	ATPase activity, coupled	42/2095	284/17697	0.0754	0.4168	0.3737	TAP1/YME1L1/TAPBP/DYNC2LI1/MYH10/PCYOX1/TAP2/ABCG1/TCIRG1/ABCC4/ATP8A1/KIF11/BLM/KIF18B/HSPA6/SMARCA1/KIF3B/BPTF/MCM5/RFC3/DYNC1I1/TOP2A/ATP1B1/ABCA8/SMARCA2/ATRX/KIF16B/MCM2/ATP1A2/HSP90AB1/MYO1C/CD320/RALBP1/ABCA3/ERCC6L/HSPA1L/KIF20B/MYO3A/LMBRD1/ATP6V1B2/KIF1B/ATP2A3	42
MF	GO:0002020	protease binding	21/2095	128/17697	0.07551	0.4168	0.3737	SERPINA1/TNFAIP3/TIMP3/SERPINA5/SRI/TIMP4/SELL/MALT1/TIMP2/COMP/RIPK2/SH3PXD2A/ADRM1/VCP/PINK1/PANX1/CFLAR/ITGAV/TP53/IL1R1/CHL1	21
MF	GO:0004033	aldo-keto reductase (NADP) activity	6/2095	26/17697	0.07879	0.4201	0.3766	AKR1C3/AKR1B1/DHRS3/AKR1C1/KCNAB1/AKR7A2	6
MF	GO:0004435	phosphatidylinositol phospholipase C activity	6/2095	26/17697	0.07879	0.4201	0.3766	CCL5/CCR5/PLCE1/PLCG2/CCR1/GDPD5	6
MF	GO:0001091	RNA polymerase II basal transcription factor binding	5/2095	20/17697	0.07883	0.4201	0.3766	AR/ZNHIT6/TAF7/ERCC1/TP53	5
MF	GO:0004745	retinol dehydrogenase activity	5/2095	20/17697	0.07883	0.4201	0.3766	AKR1C3/ADH1C/DHRS3/ADH1B/DHRS9	5
MF	GO:0005242	inward rectifier potassium channel activity	5/2095	20/17697	0.07883	0.4201	0.3766	KCNK1/KCNJ5/KCNJ15/KCNJ2/KCNJ8	5
MF	GO:0008157	protein phosphatase 1 binding	5/2095	20/17697	0.07883	0.4201	0.3766	LILRB2/PPP1CA/FER/PPP1R11/LILRB1	5
MF	GO:0008301	DNA binding, bending	5/2095	20/17697	0.07883	0.4201	0.3766	FOXC1/TOP2A/LEF1/TERF1/TFAM	5
MF	GO:0005089	Rho guanyl-nucleotide exchange factor activity	14/2095	79/17697	0.07917	0.4201	0.3766	ARHGEF18/ARHGEF9/ARHGEF26/ITSN1/DOCK1/ARHGEF3/ARHGEF10/ARHGEF12/NET1/DOCK2/VAV1/ECT2/AKAP13/VAV3	14
MF	GO:0004601	peroxidase activity	10/2095	52/17697	0.08143	0.4299	0.3855	LTC4S/HBB/GPX3/IPCEF1/GPX4/HBD/PRDX6/PTGS1/CAT/GSTM2	10
MF	GO:0140030	modification-dependent protein binding	23/2095	144/17697	0.08288	0.4341	0.3892	TNFAIP3/ING3/ANK2/CHD1/TNIP2/TRIM24/PTPN6/KMT2A/TAF7/ATRX/ZMYND11/BRD4/VCP/MTF2/MSL3/MPHOSPH8/IKBKG/TNIP3/SUZ12/KDM7A/LYN/DNAJC2/SPIN1	23
MF	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	8/2095	39/17697	0.08301	0.4341	0.3892	PARD3/FERMT2/RACGAP1/KIF16B/BTK/GAB2/DAPP1/IQGAP2	8
MF	GO:0046332	SMAD binding	14/2095	80/17697	0.08601	0.4477	0.4014	PURA/SKI/BMPR1A/TGFBR3/MAGI2/PMEPA1/SMAD3/LDLRAD4/TOB1/ACVR1/PARP1/IPO7/HIPK2/PML	14
MF	GO:0008307	structural constituent of muscle	9/2095	46/17697	0.08737	0.4505	0.4039	SYNM/DAG1/SORBS2/ASPH/MYL5/KRT19/MYH11/MYL9/MYL6B	9
MF	GO:0032813	tumor necrosis factor receptor superfamily binding	9/2095	46/17697	0.08737	0.4505	0.4039	TRAF3/STAT1/TRAF1/MYD88/BID/TNFSF10/LTB/CD40LG/CFLAR	9
MF	GO:0030414	peptidase inhibitor activity	28/2095	182/17697	0.08817	0.4518	0.4051	SERPINA1/TNFAIP8/BIRC3/TIMP3/SPOCK2/CST7/SERPINA3/SERPINA5/SLPI/PTTG1/SPOCK1/TIMP4/TIMP2/RPS6KA1/RECK/PROS1/UBE2Z/SPINT2/ITIH5/CD27/PEBP1/LEF1/SERPINI1/LXN/SERPINB1/APLP2/TFPI/SPINK5	28
MF	GO:0003823	antigen binding	25/2095	160/17697	0.08938	0.4518	0.4051	TRBC1/TAP1/TAPBP/SLAMF1/CD48/HLA-F/HLA-A/IL7R/ITGA4/HLA-C/LILRA3/HLA-G/HLA-E/HLA-DRA/IGHM/IGLL5/HLA-DPB1/HLA-B/LILRB4/KLRD1/SLC7A5/IGLC1/IGLV1-44/IGHG1/HLA-DPA1	25
MF	GO:0043177	organic acid binding	31/2095	205/17697	0.09075	0.4518	0.4051	SUSD5/S100A9/FCN1/SERPINA5/GLRB/ACOX2/HMMR/HBB/PAM/DDAH2/AKR1C1/LYVE1/PC/SLC1A3/MCCC1/SELE/PCK1/ID3/ACACB/VCAN/PCCA/HBD/STARD5/P4HTM/ADIPOQ/FABP5/ADH5/TYMS/FABP4/SESN1/STAB2	31
MF	GO:0031267	small GTPase binding	62/2095	443/17697	0.0908	0.4518	0.4051	RASGRP1/MICALL1/PLCE1/ARHGDIB/DENND1C/TBC1D16/SH3BP5/RAB8A/RASGRP3/ARHGEF18/RHOBTB3/TBC1D5/DMXL2/MAP3K11/ARHGEF9/RABGAP1/ARHGEF26/ITSN1/TBC1D9/XPO6/KIF3B/DENND1A/ARHGAP17/WAS/TBC1D8B/CDC42EP3/RHOH/DOCK1/NCKAP1L/SOD1/TBC1D1/ARHGEF3/ARHGEF10/RABGAP1L/ARHGEF12/NET1/DOCK2/VAV1/TNFAIP1/DAAM2/ECT2/KIF16B/GDI1/YIPF1/MICAL1/PAK1/MYO1C/AKAP13/ARHGAP4/DENND3/IPO7/RALBP1/DENND4B/DVL1/ABI2/RAB11FIP2/NUP50/PFN1/IQGAP2/INF2/VAV3/RAB11FIP1	62
MF	GO:0004620	phospholipase activity	17/2095	102/17697	0.09103	0.4518	0.4051	CCL5/PLA2G2D/CCR5/PLCE1/PNPLA6/PLCG2/CCR1/PLD1/PLA2G12A/PLA2G4C/LIPG/PLA1A/PRDX6/ABHD6/LIPC/GDPD5/PLA2G7	17
MF	GO:0090482	vitamin transmembrane transporter activity	6/2095	27/17697	0.09162	0.4518	0.4051	SLC2A6/RBP4/CD320/SLC23A2/LMBRD1/SLC5A6	6
MF	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	11/2095	60/17697	0.09201	0.4518	0.4051	NQO1/NDUFC1/AKR1C3/NDUFS2/CRYZL1/NDUFS4/AKR1C1/NDUFA13/NDUFA9/NDUFB6/NDUFA4	11
MF	GO:0030228	lipoprotein particle receptor activity	4/2095	15/17697	0.09207	0.4518	0.4051	LRP6/CD36/LRP10/STAB2	4
MF	GO:0042809	vitamin D receptor binding	4/2095	15/17697	0.09207	0.4518	0.4051	TAF7/MED14/TOB2/MED13	4
MF	GO:1990404	protein ADP-ribosylase activity	4/2095	15/17697	0.09207	0.4518	0.4051	PARP12/PARP4/PARP1/PARP8	4
MF	GO:0003678	DNA helicase activity	14/2095	81/17697	0.09321	0.4518	0.4051	CHD1/CDC45/BLM/MCM5/RFC3/GINS1/ATRX/NAV2/MCM2/CHD4/ACTR8/MCM4/ERCC6L/CHD9	14
MF	GO:0061650	ubiquitin-like protein conjugating enzyme activity	8/2095	40/17697	0.09352	0.4518	0.4051	UBE2L6/UBE2C/UBE2B/UBE2Z/UBE2D1/UBE2J1/UBE2E3/UBE2G2	8
MF	GO:0004602	glutathione peroxidase activity	5/2095	21/17697	0.09383	0.4518	0.4051	LTC4S/GPX3/GPX4/PRDX6/GSTM2	5
MF	GO:0005540	hyaluronic acid binding	5/2095	21/17697	0.09383	0.4518	0.4051	SUSD5/HMMR/LYVE1/VCAN/STAB2	5
MF	GO:0008106	alcohol dehydrogenase (NADP+) activity	5/2095	21/17697	0.09383	0.4518	0.4051	AKR1C3/AKR1B1/DHRS3/AKR1C1/AKR7A2	5
MF	GO:1901981	phosphatidylinositol phosphate binding	25/2095	161/17697	0.09446	0.4528	0.406	PLEKHA1/DENND1C/PARD3/PFN2/FERMT2/SH3PXD2A/DENND1A/PLEK/NCF4/LANCL2/KCNJ2/PLEKHA4/SNX5/FZD7/RACGAP1/KIF16B/PLEKHA2/BTK/TULP3/MARK1/GAB2/DAPP1/NCF1/PFN1/IQGAP2	25
MF	GO:0032182	ubiquitin-like protein binding	16/2095	96/17697	0.09886	0.4669	0.4186	TNFAIP3/UCHL1/CXCR4/UBXN7/UBE2L6/SOBP/TOP2A/TOM1L1/ADRM1/SMAD3/CKS2/IKBKG/CKS1B/HSPB1/RNF19B/PML	16
MF	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	7/2095	34/17697	0.0997	0.4669	0.4186	AMPD3/GCH1/APOBEC3G/APOBEC3B/ADA/MTHFD2/ADAR	7
MF	GO:0035091	phosphatidylinositol binding	36/2095	245/17697	0.1003	0.4669	0.4186	PLEKHA1/PIGK/MREG/DENND1C/PARD3/PFN2/FERMT2/SNX7/SH3PXD2A/SH3YL1/PASK/DENND1A/PLEK/GPAA1/PLD1/NCF4/LANCL2/PXDC1/KCNJ2/PLEKHA4/SNX5/CEACAM5/FZD7/RACGAP1/KIF16B/PLEKHA2/PITPNC1/BTK/TULP3/MARK1/GAB2/SNX10/DAPP1/NCF1/PFN1/IQGAP2	36
MF	GO:0048029	monosaccharide binding	13/2095	75/17697	0.1013	0.4669	0.4186	SCARA3/PAM/LGALS9/HK3/RPIA/SLC2A3/COLEC12/P4HTM/CLEC4A/UGP2/MANBA/TALDO1/SLC2A5	13
MF	GO:0031406	carboxylic acid binding	29/2095	193/17697	0.1052	0.4669	0.4186	SUSD5/S100A9/FCN1/SERPINA5/GLRB/ACOX2/HMMR/PAM/DDAH2/AKR1C1/LYVE1/PC/SLC1A3/MCCC1/SELE/PCK1/ID3/ACACB/VCAN/PCCA/STARD5/P4HTM/ADIPOQ/FABP5/ADH5/TYMS/FABP4/SESN1/STAB2	29
MF	GO:0004690	cyclic nucleotide-dependent protein kinase activity	3/2095	10/17697	0.1052	0.4669	0.4186	AKAP13/PRKG1/PRKG2	3
MF	GO:0004691	cAMP-dependent protein kinase activity	3/2095	10/17697	0.1052	0.4669	0.4186	AKAP13/PRKG1/PRKG2	3
MF	GO:0005347	ATP transmembrane transporter activity	3/2095	10/17697	0.1052	0.4669	0.4186	SLC25A4/SLC25A23/SLC25A5	3
MF	GO:0005351	carbohydrate:proton symporter activity	3/2095	10/17697	0.1052	0.4669	0.4186	SLC17A5/SLC2A6/SLC2A10	3
MF	GO:0016176	superoxide-generating NADPH oxidase activator activity	3/2095	10/17697	0.1052	0.4669	0.4186	SH3PXD2A/NCF4/NCF1	3
MF	GO:0016303	1-phosphatidylinositol-3-kinase activity	3/2095	10/17697	0.1052	0.4669	0.4186	PIK3CD/PIK3CA/PIK3R3	3
MF	GO:0032395	MHC class II receptor activity	3/2095	10/17697	0.1052	0.4669	0.4186	HLA-DRA/HLA-DQB2/HLA-DPA1	3
MF	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	3/2095	10/17697	0.1052	0.4669	0.4186	PIK3R1/PTPN13/FBXL2	3
MF	GO:0051400	BH domain binding	3/2095	10/17697	0.1052	0.4669	0.4186	BCL2A1/BAK1/BCL2L2	3
MF	GO:0070016	armadillo repeat domain binding	3/2095	10/17697	0.1052	0.4669	0.4186	TCF7L2/LEF1/CALCOCO1	3
MF	GO:0004629	phospholipase C activity	6/2095	28/17697	0.1055	0.4669	0.4186	CCL5/CCR5/PLCE1/PLCG2/CCR1/GDPD5	6
MF	GO:0005520	insulin-like growth factor binding	6/2095	28/17697	0.1055	0.4669	0.4186	IGFBP5/IGFBP6/HTRA1/KAZALD1/IGFBP2/ITGAV	6
MF	GO:0017091	AU-rich element binding	6/2095	28/17697	0.1055	0.4669	0.4186	RBMS3/HNRNPA0/CPEB1/ZFP36L1/ZFP36L2/EXOSC7	6
MF	GO:0043425	bHLH transcription factor binding	6/2095	28/17697	0.1055	0.4669	0.4186	SOX9/CREBBP/SP1/SMAD3/BHLHE41/ARNTL	6
MF	GO:0004177	aminopeptidase activity	9/2095	48/17697	0.1078	0.4752	0.4261	LAP3/DPP3/XPNPEP3/ERAP2/NAALAD2/TRHDE/ANPEP/METAP2/CTSH	9
MF	GO:0015145	monosaccharide transmembrane transporter activity	5/2095	22/17697	0.1102	0.4754	0.4262	SLC2A6/SLC2A3/SLC5A3/SLC23A2/SLC2A5	5
MF	GO:0008235	metalloexopeptidase activity	11/2095	62/17697	0.1102	0.4754	0.4262	LAP3/XPNPEP3/CPD/ERAP2/CPE/CPQ/CPA3/TRHDE/ANPEP/FOLH1/METAP2	11
MF	GO:0005149	interleukin-1 receptor binding	4/2095	16/17697	0.1118	0.4754	0.4262	TLR5/TRIP6/IL1RN/IL1B	4
MF	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	4/2095	16/17697	0.1118	0.4754	0.4262	CASP1/APAF1/NOD1/CTSH	4
MF	GO:0015377	cation:chloride symporter activity	4/2095	16/17697	0.1118	0.4754	0.4262	SLC18A2/SLC12A2/SLC12A8/SLC12A7	4
MF	GO:0016307	phosphatidylinositol phosphate kinase activity	4/2095	16/17697	0.1118	0.4754	0.4262	PIP4K2B/PIK3CD/PIK3CA/PIP4K2A	4
MF	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	4/2095	16/17697	0.1118	0.4754	0.4262	MAOA/AOC2/MAOB/AOC3	4
MF	GO:0035259	glucocorticoid receptor binding	4/2095	16/17697	0.1118	0.4754	0.4262	TACC1/SMAD3/FLT3/NRIP1	4
MF	GO:0071837	HMG box domain binding	4/2095	16/17697	0.1118	0.4754	0.4262	MEOX1/SP1/HOXC4/POU3F3	4
MF	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	7/2095	35/17697	0.1126	0.4768	0.4275	ALDH7A1/ALDH3A2/AKR1C3/ALDH6A1/AKR1B1/ADH5/ALDH5A1	7
MF	GO:0003697	single-stranded DNA binding	18/2095	113/17697	0.1166	0.4906	0.4399	SSBP2/PURA/NUCKS1/CDC45/BLM/IGHM/MCM5/HMCES/RNF138/TDP1/MCM2/TERF1/MCM4/RAD51AP1/ERCC1/SMC4/SETMAR/MCM10	18
MF	GO:0019894	kinesin binding	8/2095	42/17697	0.1167	0.4906	0.4399	TRAK2/KIF18B/CLSTN1/ARHGEF10/PRC1/SYBU/AP1AR/KIF1B	8
MF	GO:0016836	hydro-lyase activity	10/2095	56/17697	0.1199	0.5023	0.4503	CBS/PCBD1/ECHDC2/CA14/CA2/ECI1/ALAD/ECHS1/CA5BP1/HADHA	10
MF	GO:0035035	histone acetyltransferase binding	6/2095	29/17697	0.1204	0.5024	0.4504	STAT1/GLI3/TAF7/SP1/EID1/TP53	6
MF	GO:0008237	metallopeptidase activity	27/2095	181/17697	0.1221	0.5073	0.4548	ADAMDEC1/YME1L1/LAP3/ADAM19/DPP3/MMP1/ADAM28/XPNPEP3/ADAM8/CPD/ERAP2/CNDP2/AFG3L2/NAALAD2/PAPPA/CPE/ADAM22/CPQ/CPA3/TRHDE/ANPEP/ADAM10/FOLH1/METAP2/MBTPS2/ADAM23/MMP12	27
MF	GO:0043178	alcohol binding	14/2095	85/17697	0.1256	0.5106	0.4578	ABCG1/NFE2L1/NPC1/ERLIN1/TRPC1/RBP4/STARD5/ERLIN2/CETP/SCARB2/NR1H3/OSBPL1A/CD81/SOAT2	14
MF	GO:0004857	enzyme inhibitor activity	52/2095	375/17697	0.1265	0.5106	0.4578	SERPINA1/CDKN2C/LRP6/CDKN1C/TNFAIP8/BIRC3/TIMP3/SPOCK2/CST7/SERPINA3/SERPINA5/SLPI/PTTG1/SKI/SH3BP5/SPOCK1/TIMP4/TIMP2/ANXA3/SOCS1/RPS6KA1/RECK/PROS1/PHACTR2/UBE2Z/SPINT2/ITIH5/RHOH/PLN/CD27/PTN/GMFG/PEBP1/LEF1/ANGPTL4/NOTCH1/HEXIM1/SERPINI1/LXN/MBIP/FBXO5/SERPINB1/HSPB1/ANXA4/TESC/APLP2/ENSA/TFPI/PPP1R11/PINLYP/SPINK5/IQGAP2	52
MF	GO:0044183	protein binding involved in protein folding	5/2095	23/17697	0.1278	0.5106	0.4578	CD74/HSPA6/HSPB1/RIC3/HSPA1L	5
MF	GO:0070006	metalloaminopeptidase activity	5/2095	23/17697	0.1278	0.5106	0.4578	XPNPEP3/ERAP2/TRHDE/ANPEP/METAP2	5
MF	GO:0005088	Ras guanyl-nucleotide exchange factor activity	21/2095	137/17697	0.1293	0.5106	0.4578	RASGRP1/DENND1C/SH3BP5/RASGRP3/ARHGEF18/ARHGEF9/ARHGEF26/ITSN1/DENND1A/DOCK1/ARHGEF3/ARHGEF10/ARHGEF12/NET1/DOCK2/VAV1/ECT2/AKAP13/DENND3/DENND4B/VAV3	21
MF	GO:0015932	nucleobase-containing compound transmembrane transporter activity	8/2095	43/17697	0.1294	0.5106	0.4578	SLC29A1/SLC25A36/SLC25A4/SLC25A23/SLC29A2/SLC25A5/SLC35A2/HNRNPA3	8
MF	GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	8/2095	43/17697	0.1294	0.5106	0.4578	ALDH7A1/ALDH3A2/AKR1C3/ALDH6A1/AKR1B1/ADH5/BCKDHB/ALDH5A1	8
MF	GO:0001094	TFIID-class transcription factor complex binding	3/2095	11/17697	0.1325	0.5106	0.4578	ZNHIT6/ERCC1/TP53	3
MF	GO:0004312	fatty acid synthase activity	3/2095	11/17697	0.1325	0.5106	0.4578	ELOVL4/ELOVL2/ELOVL5	3
MF	GO:0005035	death receptor activity	3/2095	11/17697	0.1325	0.5106	0.4578	TNFRSF1B/TNFRSF14/TNFRSF4	3
MF	GO:0005247	voltage-gated chloride channel activity	3/2095	11/17697	0.1325	0.5106	0.4578	CLCN4/CLCN7/CLCN5	3
MF	GO:0005522	profilin binding	3/2095	11/17697	0.1325	0.5106	0.4578	ENAH/VASP/CTTN	3
MF	GO:0005536	glucose binding	3/2095	11/17697	0.1325	0.5106	0.4578	HK3/SLC2A3/UGP2	3
MF	GO:0017166	vinculin binding	3/2095	11/17697	0.1325	0.5106	0.4578	SYNM/DAG1/CORO2B	3
MF	GO:0030955	potassium ion binding	3/2095	11/17697	0.1325	0.5106	0.4578	HDAC4/ATP1B1/ATP1A2	3
MF	GO:0035004	phosphatidylinositol 3-kinase activity	3/2095	11/17697	0.1325	0.5106	0.4578	PIK3CD/PIK3CA/PIK3R3	3
MF	GO:0036122	BMP binding	3/2095	11/17697	0.1325	0.5106	0.4578	GDF5/COMP/NBL1	3
MF	GO:0043295	glutathione binding	3/2095	11/17697	0.1325	0.5106	0.4578	GSTM3/LANCL1/GSTM2	3
MF	GO:0050786	RAGE receptor binding	3/2095	11/17697	0.1325	0.5106	0.4578	S100A9/S100A13/FPR1	3
MF	GO:0052650	NADP-retinol dehydrogenase activity	3/2095	11/17697	0.1325	0.5106	0.4578	AKR1C3/AKR1B1/DHRS3	3
MF	GO:0048038	quinone binding	4/2095	17/17697	0.1331	0.5106	0.4578	NDUFS2/VKORC1/AOC2/AOC3	4
MF	GO:0050811	GABA receptor binding	4/2095	17/17697	0.1331	0.5106	0.4578	GABARAPL1/PPP2CA/TRAK2/GABARAPL2	4
MF	GO:0019209	kinase activator activity	14/2095	86/17697	0.1346	0.5146	0.4614	CCL5/MALT1/ITSN1/GPRC5A/FGF13/CCNT1/NCKAP1L/TOM1L1/EFNA5/CKS2/CCNB1/PIK3CA/DBF4/CKS1B	14
MF	GO:0016878	acid-thiol ligase activity	6/2095	30/17697	0.1363	0.5191	0.4654	ACSS3/SUCLA2/SLC27A5/ACSM5/ACSM3/ACSL5	6
MF	GO:0035064	methylated histone binding	11/2095	65/17697	0.141	0.5334	0.4783	ING3/CHD1/TAF7/ATRX/ZMYND11/MTF2/MSL3/MPHOSPH8/SUZ12/KDM7A/SPIN1	11
MF	GO:0140034	methylation-dependent protein binding	11/2095	65/17697	0.141	0.5334	0.4783	ING3/CHD1/TAF7/ATRX/ZMYND11/MTF2/MSL3/MPHOSPH8/SUZ12/KDM7A/SPIN1	11
MF	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	10/2095	58/17697	0.1424	0.5341	0.4788	LBR/AKR1C3/ACADVL/ACOX2/AKR1C1/DUS1L/BDH2/RETSAT/ACADL/SDHA	10
MF	GO:1901505	carbohydrate derivative transmembrane transporter activity	8/2095	44/17697	0.1427	0.5341	0.4788	SLC17A5/SLC29A1/SLC37A1/SLC25A4/SLC25A23/SLC29A2/SLC25A5/SLC35A2	8
MF	GO:1990939	ATP-dependent microtubule motor activity	8/2095	44/17697	0.1427	0.5341	0.4788	DYNC2LI1/KIF11/KIF18B/KIF3B/DYNC1I1/KIF16B/KIF20B/KIF1B	8
MF	GO:0003688	DNA replication origin binding	5/2095	24/17697	0.1466	0.5412	0.4852	CDC45/MCM5/MCM2/MCM4/MCM10	5
MF	GO:0051119	sugar transmembrane transporter activity	5/2095	24/17697	0.1466	0.5412	0.4852	SLC2A6/SLC2A3/SLC5A3/SLC23A2/SLC2A5	5
MF	GO:0005200	structural constituent of cytoskeleton	16/2095	102/17697	0.1466	0.5412	0.4852	ADD3/SYNM/ANK2/TUBA4A/TUBB2B/SORBS2/TUBB4A/CCDC6/KRT6A/KRT19/VILL/GFAP/TUBG2/ACTR3/SPTBN1/ACTR2	16
MF	GO:0042562	hormone binding	16/2095	102/17697	0.1466	0.5412	0.4852	PIK3R1/INHBA/NPR2/AR/EGFR/GHR/CHRNA5/ATP1A2/ACVR1/EDNRB/HCRTR1/NPR3/PTH1R/VIPR1/THRA/CTSH	16
MF	GO:1902936	phosphatidylinositol bisphosphate binding	17/2095	110/17697	0.1516	0.556	0.4985	PLEKHA1/PARD3/PFN2/SH3PXD2A/PLEK/KCNJ2/PLEKHA4/SNX5/FZD7/KIF16B/PLEKHA2/TULP3/MARK1/GAB2/DAPP1/NCF1/PFN1	17
MF	GO:0001883	purine nucleoside binding	52/2095	381/17697	0.1527	0.556	0.4985	GVINP1/MPPED2/GBP1/ARL1/GCH1/GNAL/RAC2/GBP2/RAB8A/RHOBTB3/RERGL/MX2/NPR2/GIMAP4/RHOF/TUBA4A/GEM/DNM1/TUBB2B/DIRAS3/ADA/RAB40B/GTPBP2/AGAP1/RHOH/RAB33B/TUBB4A/EHD4/PCK1/LANCL2/EIF5B/RRAS/RAB20/RAB27A/MFHAS1/TRIM23/ARL15/RHOG/HSP90AB1/GIMAP6/RAB28/RHOD/ARL4A/SPAG1/TUBG2/ARL4C/MX1/TUFM/ARL3/ACSM5/TGM2/RAB14	52
MF	GO:0001882	nucleoside binding	53/2095	389/17697	0.1531	0.556	0.4985	GVINP1/MPPED2/GBP1/ARL1/GCH1/GNAL/RAC2/GBP2/RAB8A/RHOBTB3/RERGL/MX2/NPR2/GIMAP4/RHOF/TUBA4A/GEM/DNM1/TUBB2B/DIRAS3/ADA/RAB40B/GTPBP2/AGAP1/RHOH/RAB33B/TUBB4A/EHD4/PCK1/LANCL2/EIF5B/RRAS/RAB20/RAB27A/MFHAS1/TRIM23/ARL15/RHOG/PNP/HSP90AB1/GIMAP6/RAB28/RHOD/ARL4A/SPAG1/TUBG2/ARL4C/MX1/TUFM/ARL3/ACSM5/TGM2/RAB14	53
MF	GO:0005164	tumor necrosis factor receptor binding	6/2095	31/17697	0.1531	0.556	0.4985	TRAF3/STAT1/TRAF1/TNFSF10/LTB/CD40LG	6
MF	GO:0015248	sterol transporter activity	6/2095	31/17697	0.1531	0.556	0.4985	ABCG1/NPC1/STARD5/CETP/OSBPL1A/OSBPL9	6