ONTOLOGY	ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	qvalue	geneID	Count
KEGG	hsa05131	Shigellosis	55/972	247/8135	2.53e-06	0.0008351	0.0007059	WASF1/TLR4/CD14/CASP4/RRAGA/C3/CHUK/MYD88/WASF2/ARF1/ARPC5L/CDC42/ACTR2/DIAPH1/CRKL/RBX1/TNF/RPS27A/TLN1/U2AF1L4/NAIP/ITPR3/CCL5/MAP1LC3B2/ITPR1/SQSTM1/RRAGD/SRC/MYL7/BCL2/ROCK1/TNFRSF1A/ELMO2/TECPR1/ACTG1/MAP1LC3A/ARPC5/PPID/FNBP1/JUN/UBE2D2/BCL2L1/NFKBIB/ATG16L1/MYL10/FOXO1/UBA52/PRKCE/RBCK1/EGFR/ARPC1A/ARHGEF2/MAP3K7/BTRC/DOCK1	55
KEGG	hsa04936	Alcoholic liver disease	36/972	142/8135	6.946e-06	0.001146	0.0009687	C1QB/C1QA/C1QC/C2/C3AR1/TLR4/CXCL1/CD14/C3/CHUK/TRA2B/MYD88/ACACB/PRKAA1/ADIPOR2/CPT1C/TNF/CXCL3/MAP3K14/TRA2A/FAS/C5AR1/CXCL2/ACOX1/TNFRSF1A/CAMKK2/MAP3K5/PPARGC1A/IL17RC/MAP2K6/FOXO1/ADH1A/PRKAB2/IRAK4/TCF7L1/MAP3K7	36
KEGG	hsa05140	Leishmaniasis	23/972	77/8135	1.935e-05	0.002128	0.001799	FCGR1A/TLR4/TLR2/C3/MYD88/CR1L/IL10/PRKCB/HLA-DPB1/TNF/JAK2/ITGA4/MARCKSL1/FCGR2C/JUN/CR1/NCF4/NFKBIB/HLA-DMB/IRAK4/IL4/HLA-DMA/MAP3K7	23
KEGG	hsa05171	Coronavirus disease - COVID-19	47/972	232/8135	0.0001633	0.01347	0.01139	C1QB/C1QA/C1QC/C2/RPS28/C3AR1/TLR4/NRP1/TLR2/CFB/C3/RPS27/CHUK/MYD88/RPLP1/RPS15A/PRKCB/RPL14/HBEGF/IRF9/TNF/RPS27A/RPS29/C5AR1/IFNAR2/RPL36A/TNFRSF1A/RPS2/RPLP0/JUN/RPS26/NFKBIB/RPL3L/RPS13/UBA52/RPL38/PRKCA/IRAK4/EGFR/RPS3A/RPL12/RPL37/F13A1/MAP3K7/AGTR1/RPL10A/RPSA	47
KEGG	hsa04921	Oxytocin signaling pathway	33/972	154/8135	0.0005335	0.03521	0.02977	CAMK1D/CACNG3/ADCY3/NOS3/PRKAA1/PRKCB/PPP1R12C/RGS2/ITPR3/CACNA1F/ITPR1/SRC/CACNA2D3/ROCK1/CAMKK2/ACTG1/CALML3/RYR1/EEF2/CACNG2/JUN/NFATC3/PPP3R1/CAMK2G/CALML5/ADCY1/PRKCA/EEF2K/CACNG1/PRKAB2/EGFR/RAF1/MYL6B	33
KEGG	hsa05134	Legionellosis	16/972	57/8135	0.000756	0.04158	0.03515	TLR4/CXCL1/TLR2/CD14/C3/MYD88/CR1L/ARF1/TNF/CXCL3/RAB1B/NAIP/CXCL2/NFKB2/CR1/CLK1	16
KEGG	hsa04640	Hematopoietic cell lineage	23/972	99/8135	0.001153	0.04776	0.04037	FCGR1A/CD14/CR1L/CD1B/CD9/HLA-DPB1/CD1C/TNF/CD24/GP1BB/ANPEP/ITGA3/CD37/ITGA4/IL1R2/CR1/THPO/CD55/CD1E/HLA-DMB/CSF1R/IL4/HLA-DMA	23
KEGG	hsa04010	MAPK signaling pathway	53/972	294/8135	0.001261	0.04776	0.04037	AREG/CD14/CACNG3/CHUK/MYD88/FGF6/MAP3K3/DUSP9/PRKCB/CACNA1I/CDC42/MKNK2/MAP4K4/CRKL/MAPK8IP3/TNF/FGF22/NTF3/MAP3K6/MAP3K14/STMN1/FAS/CACNA1F/TAOK3/IGF1/CACNA2D3/TNFRSF1A/FLNA/FLT1/IL1RAP/MAP3K5/HGF/NFKB2/FGF3/CACNG2/RPS6KA3/VEGFC/JUN/NFATC3/PPP3R1/MAP2K6/FLNB/TGFA/PRKCA/CACNG1/CACNA1H/RPS6KA4/CSF1R/IRAK4/EGFR/MAP4K1/MAP3K7/RAF1	53
KEGG	hsa05167	Kaposi sarcoma-associated herpesvirus infection	38/972	194/8135	0.001303	0.04776	0.04037	CXCL1/C3/HLA-B/CHUK/CCR1/HLA-G/IRF9/CXCL3/HLA-C/JAK2/RPS27A/E2F2/ITPR3/MAP1LC3B2/FAS/ITPR1/CDK6/CXCL2/IFNAR2/SRC/TNFRSF1A/GNB2/CALML3/ATG3/MAP1LC3A/GNG10/CCR5/JUN/NFATC3/PPP3R1/MAP2K6/E2F1/UBA52/CALML5/ZFP36/TCF7L1/RAF1/EP300	38
KEGG	hsa05150	Staphylococcus aureus infection	22/972	96/8135	0.001765	0.05589	0.04724	C1QB/C1QA/C1QC/FCGR1A/C2/FPR2/C3AR1/CFH/CFB/C3/IL10/FPR1/HLA-DPB1/KRT32/PTAFR/C5AR1/CAMP/FCGR2C/FCGR2B/HLA-DMB/HLA-DMA/DEFA4	22
KEGG	hsa04610	Complement and coagulation cascades	20/972	85/8135	0.002007	0.05589	0.04724	C1QB/C1QA/C1QC/C2/C3AR1/CFH/PROS1/CFB/C3/CLU/CR1L/THBD/SERPINB2/C5AR1/CR1/CD55/PLAU/KLKB1/F13A1/SERPING1	20
KEGG	hsa04666	Fc gamma R-mediated phagocytosis	22/972	97/8135	0.002032	0.05589	0.04724	FCGR1A/WASF1/AMPH/WASF2/PRKCB/ARPC5L/CDC42/ACTR2/ASAP1/INPP5D/CRKL/VAV3/SCIN/MARCKSL1/ARPC5/GSN/FCGR2B/PRKCA/PRKCE/ARPC1A/RAF1/DOCK1	22
KEGG	hsa04064	NF-kappa B signaling pathway	23/972	104/8135	0.002309	0.0586	0.04954	TLR4/CXCL1/CD14/TNFRSF13C/CHUK/MYD88/PRKCB/TNFAIP3/UBE2I/CCL21/TNF/CXCL3/MAP3K14/BCL2A1/CXCL2/CARD14/BCL2/TNFRSF1A/NFKB2/BCL2L1/PLAU/IRAK4/MAP3K7	23
KEGG	hsa04530	Tight junction	33/972	169/8135	0.002774	0.06413	0.05421	SLC9A3R1/CD1B/PRKAA1/MYH9/ARPC5L/RAB13/CD1C/CDC42/ACTR2/PPP2CB/CLDN17/WHAMM/SRC/ROCK1/CLDN3/CRB3/HSPA4/ACTG1/PARD3/MAP3K5/ARPC5/JUN/MARVELD2/LLGL2/CD1E/CLDN10/PRKCE/PRKAB2/ARPC1A/ARHGEF2/RUNX1/ARHGEF18/MYL6B	33
KEGG	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	17/972	70/8135	0.002976	0.06413	0.05421	CXCL1/ATP6V1E1/CHUK/CDC42/ADAM10/HBEGF/CXCL3/ATP6V1C1/MAP3K14/CCL5/CXCL2/SRC/ATP6V1B1/ATP6V1G3/JUN/CXCR1/EGFR	17
KEGG	hsa05130	Pathogenic Escherichia coli infection	37/972	197/8135	0.003213	0.06413	0.05421	WASF1/TLR4/WIPF1/CASP4/SLC9A3R1/CHUK/MYD88/WASF2/ARF1/MYH9/ARPC5L/MYO1D/CDC42/ACTR2/CLDN17/TNF/TNFRSF10A/NAIP/NCK2/FYN/FAS/SRC/ROCK1/CLDN3/ARHGEF12/TNFRSF1A/ACTG1/ARPC5/JUN/NFKBIB/CLDN10/ABCF2/IRAK4/ARPC1A/ARHGEF2/MAP3K7/SEC24B	37
KEGG	hsa04621	NOD-like receptor signaling pathway	35/972	184/8135	0.003304	0.06413	0.05421	CARD6/TLR4/CXCL1/CASP4/CHUK/TRIP6/MYD88/HSP90AB1/P2RX7/TNFAIP3/IRF9/TNF/CXCL3/NAIP/ITPR3/CCL5/MAP1LC3B2/ITPR1/GBP2/CXCL2/IFNAR2/CAMP/BCL2/CASR/MAP1LC3A/IFI16/JUN/BCL2L1/NFKBIB/ATG16L1/NOD2/RBCK1/IRAK4/MAP3K7/DEFA4	35
KEGG	hsa05330	Allograft rejection	11/972	38/8135	0.003796	0.06958	0.05882	HLA-B/IL10/HLA-DPB1/HLA-G/TNF/HLA-C/FAS/GZMB/HLA-DMB/IL4/HLA-DMA	11
KEGG	hsa04380	Osteoclast differentiation	26/972	128/8135	0.004326	0.07514	0.06351	FCGR1A/LILRA6/LILRA3/CHUK/LILRB4/IRF9/TNF/PPARG/MAP3K14/FYN/LILRB2/IFNAR2/SQSTM1/TNFRSF1A/FCGR2C/SOCS3/NFKB2/JUN/NCF4/PPP3R1/MAP2K6/FCGR2B/LILRB5/CSF1R/MITF/MAP3K7	26
KEGG	hsa05417	Lipid and atherosclerosis	39/972	215/8135	0.004723	0.07532	0.06367	HSP90B1/TLR4/CXCL1/TLR2/CD14/CHUK/MYD88/NOS3/HSP90AB1/CDC42/PDPK1/TNF/CXCL3/JAK2/TNFRSF10A/PPARG/VAV3/CCL5/FAS/ITPR1/CXCL2/SRC/BCL2/TNFRSF1A/HSPA4/CALML3/MAP3K5/JUN/BCL2L1/NCF4/NFATC3/PPP3R1/MAP2K6/CAMK2G/APOA4/CALML5/PRKCA/IRAK4/MAP3K7	39
KEGG	hsa05166	Human T-cell leukemia virus 1 infection	40/972	222/8135	0.004793	0.07532	0.06367	NRP1/TRRAP/HLA-B/TNFRSF13C/CHUK/ADCY3/ANAPC13/MAP3K3/HLA-DPB1/CREB3L2/EGR2/HLA-G/IL2RG/CDKN2B/ATR/TNF/HLA-C/TLN1/MAD2L1/E2F2/MAP3K14/SLC25A5/TNFRSF1A/ANAPC1/NFKB2/IL1R2/JUN/BCL2L1/BUB3/NFATC3/PPP3R1/E2F1/CDC26/CCND3/HLA-DMB/ADCY1/MSX1/ZFP36/HLA-DMA/EP300	40
KEGG	hsa05135	Yersinia infection	27/972	137/8135	0.005659	0.08489	0.07176	TLR4/WIPF1/CHUK/MYD88/IL10/WASF2/ARPC5L/CDC42/ACTR2/CRKL/TNF/VAV3/SRC/ITGA4/ROCK1/ARHGEF12/ELMO2/ACTG1/ARPC5/RPS6KA3/JUN/NFATC3/MAP2K6/IRAK4/ARPC1A/MAP3K7/DOCK1	27
KEGG	hsa05418	Fluid shear stress and atherosclerosis	27/972	139/8135	0.006912	0.09706	0.08205	HSP90B1/CHUK/NOS3/THBD/HSP90AB1/PRKAA1/GSTP1/MEF2A/TNF/TRPV4/SQSTM1/SRC/BCL2/TNFRSF1A/ACTG1/CALML3/MAP3K5/GSTT1/IL1R2/JUN/MAP2K6/MGST1/SDC2/CALML5/ARHGEF2/MAP3K7/GSTO2	27
KEGG	hsa05133	Pertussis	17/972	76/8135	0.007257	0.09706	0.08205	C1QB/C1QA/C1QC/C2/TLR4/CD14/C3/MYD88/IL10/TNF/CALML3/CXCL6/JUN/CALML5/CXCL5/IRAK4/SERPING1	17
KEGG	hsa05152	Tuberculosis	33/972	180/8135	0.007576	0.09706	0.08205	FCGR1A/TLR4/TLR2/CD14/C3/MYD88/CR1L/IL10/HLA-DPB1/CTSD/TNF/JAK2/TLR9/IL10RA/CAMP/SRC/BCL2/ARHGEF12/TNFRSF1A/FCGR2C/CALML3/CR1/PPP3R1/FCGR2B/CAMK2G/NOD2/HLA-DMB/CALML5/IRAK4/HLA-DMA/CD74/RAF1/EP300	33
KEGG	hsa05132	Salmonella infection	43/972	249/8135	0.007685	0.09706	0.08205	HSP90B1/TLR4/TLR2/CD14/CASP4/AHNAK/CHUK/MYD88/HSP90AB1/ARF1/ARPC5L/CDC42/ACTR2/TNF/TNFRSF10A/TLR9/NAIP/AHNAK2/ACTR10/DCTN6/MYL7/BCL2/TNFRSF1A/FLNA/ELMO2/ACTG1/ARPC5/ACTR1A/JUN/MAP2K6/RALA/MYL10/ANXA2/KLC3/FLNB/PIK3C2B/ACTR1B/RHOB/IRAK4/ARPC1A/TCF7L1/MAP3K7/RAF1	43
KEGG	hsa04510	Focal adhesion	36/972	201/8135	0.007942	0.09706	0.08205	COL9A2/ITGA7/PRKCB/CDC42/DIAPH1/LAMC1/CRKL/PDPK1/PPP1R12C/TLN1/VAV3/ITGA3/FYN/ITGB6/IGF1/SRC/ITGA4/MYL7/BCL2/ROCK1/FLNA/FLT1/ACTG1/HGF/VEGFC/JUN/MYL10/FLNB/CCND3/TNR/PRKCA/ZYX/EGFR/THBS1/RAF1/DOCK1	36
KEGG	hsa04360	Axon guidance	33/972	182/8135	0.008947	0.1055	0.08914	EPHB2/NRP1/RGMA/SLIT1/PLXNA3/NTN3/ROBO3/CDC42/SEMA3B/PDPK1/SEMA3C/NCK2/SRGAP3/FYN/SEMA5B/WNT5B/SRC/SEMA4D/ROCK1/ARHGEF12/PLXNA1/PARD3/NEO1/NFATC3/PPP3R1/EPHA1/CAMK2G/PRKCA/PLXNB1/RND1/RAF1/SEMA4A/SEMA3D	33
KEGG	hsa05215	Prostate cancer	20/972	97/8135	0.009724	0.1107	0.09353	HSP90B1/CHUK/HSP90AB1/GSTP1/CREB3L2/ETV5/PDPK1/E2F2/IGF1/BCL2/IL1R2/CDKN1B/E2F1/FOXO1/TGFA/PLAU/EGFR/TCF7L1/RAF1/EP300	20
KEGG	hsa04940	Type I diabetes mellitus	11/972	43/8135	0.0104	0.1144	0.09667	HLA-B/ICA1/CPE/HLA-DPB1/HLA-G/TNF/HLA-C/FAS/GZMB/HLA-DMB/HLA-DMA	11
KEGG	hsa04114	Oocyte meiosis	25/972	131/8135	0.01139	0.1177	0.09947	ADCY3/ANAPC13/BUB1/PPP2CB/SPDYE1/RBX1/MAD2L1/YWHAH/ITPR3/ITPR1/PPP2R5C/IGF1/ANAPC1/FBXO5/CALML3/RPS6KA3/PPP3R1/CAMK2G/CDC26/MOS/CALML5/ADCY1/STAG3/BTRC/CCNB1	25
KEGG	hsa04668	TNF signaling pathway	22/972	112/8135	0.01223	0.1177	0.09947	CXCL1/CHUK/CREB3L2/TNFAIP3/TNF/CXCL3/MAP3K14/CCL5/FAS/CXCL2/TNFRSF1A/SOCS3/MAP3K5/CXCL6/VEGFC/JUN/MAP2K6/NOD2/CXCL5/RPS6KA4/CX3CL1/MAP3K7	22
KEGG	hsa05145	Toxoplasmosis	22/972	112/8135	0.01223	0.1177	0.09947	TLR4/TLR2/CHUK/MYD88/IL10/HLA-DPB1/LAMC1/PDPK1/TNF/JAK2/IL10RA/BCL2/TNFRSF1A/CCR5/BIRC7/BCL2L1/NFKBIB/MAP2K6/HLA-DMB/IRAK4/HLA-DMA/MAP3K7	22
KEGG	hsa05323	Rheumatoid arthritis	19/972	93/8135	0.01272	0.1177	0.09947	TLR4/CXCL1/TLR2/ATP6V1E1/HLA-DPB1/TNF/CXCL3/ATP6V1C1/CCL5/CXCL2/ATP6V1B1/FLT1/CTLA4/ATP6V1G3/CXCL6/JUN/HLA-DMB/CXCL5/HLA-DMA	19
KEGG	hsa04071	Sphingolipid signaling pathway	23/972	119/8135	0.01279	0.1177	0.09947	NOS3/PRKCB/SGMS1/PPP2CB/CTSD/PDPK1/PPP2R3C/TNF/FYN/PPP2R5C/BCL2/ROCK1/TNFRSF1A/MS4A2/MAP3K5/FCER1A/SGPP2/ACER1/PRKCA/PRKCE/ADORA3/SGMS2/RAF1	23
KEGG	hsa05144	Malaria	12/972	50/8135	0.01284	0.1177	0.09947	TLR4/TLR2/HBB/MYD88/CR1L/IL10/TNF/TLR9/HGF/CR1/SDC2/THBS1	12
KEGG	hsa04061	Viral protein interaction with cytokine and cytokine receptor	20/972	100/8135	0.01355	0.1209	0.1022	CXCL1/IL10/CCR1/CCL21/IL2RG/TNF/CXCL3/TNFRSF10A/IL10RA/CCL5/CXCL2/XCR1/TNFRSF1A/CXCL6/CCR5/CXCL5/CXCR1/CSF1R/CX3CL1/CCL8	20
KEGG	hsa05169	Epstein-Barr virus infection	35/972	202/8135	0.01445	0.1238	0.1047	TLR2/HLA-B/PSMD14/CHUK/MYD88/HLA-DPB1/TNFAIP3/HLA-G/PSMD12/IRF9/TNF/HLA-C/E2F2/MAP3K14/FAS/CDK6/IFNAR2/BCL2/NFKB2/CD58/NFKBIE/JUN/NFKBIB/MAP2K6/PSMC1/CDKN1B/E2F1/CCND3/HLA-DMB/PDIA3/USP7/IRAK4/HLA-DMA/PSMD1/MAP3K7	35
KEGG	hsa04920	Adipocytokine signaling pathway	15/972	69/8135	0.01464	0.1238	0.1047	CHUK/ACACB/PRKAA1/ADIPOR2/CPT1C/TNF/JAK2/TNFRSF1A/CAMKK2/SOCS3/ACSL1/NFKBIE/PPARGC1A/NFKBIB/PRKAB2	15
KEGG	hsa04662	B cell receptor signaling pathway	17/972	82/8135	0.01551	0.128	0.1082	LILRA6/LILRA3/CHUK/LILRB4/PRKCB/INPP5D/IFITM1/VAV3/LILRB2/NFKBIE/JUN/NFATC3/NFKBIB/PPP3R1/FCGR2B/LILRB5/RAF1	17
KEGG	hsa05146	Amoebiasis	20/972	102/8135	0.01671	0.1345	0.1137	TLR4/CXCL1/TLR2/CD14/MUC2/IL10/CD1B/PRKCB/CD1C/LAMC1/TNF/CXCL3/ARG2/CXCL2/IL1R2/ARG1/SERPINB6/CD1E/ADCY1/PRKCA	20
KEGG	hsa05170	Human immunodeficiency virus 1 infection	36/972	212/8135	0.01783	0.1392	0.1176	TLR4/TLR2/HLA-B/CHUK/MYD88/PRKCB/HLA-G/CRKL/RBX1/ATR/TNF/HLA-C/APOBEC3A/ITPR3/FAS/ITPR1/BCL2/TNFRSF1A/GNB2/CALML3/RNF7/GNG10/CCR5/JUN/BCL2L1/NFATC3/PPP3R1/MAP2K6/CALML5/PDIA3/PRKCA/IRAK4/MAP3K7/BTRC/RAF1/CCNB1	36
KEGG	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	16/972	77/8135	0.01815	0.1392	0.1176	CACNG3/ITGA7/DAG1/JUP/ATP2A1/ITGA3/CACNA1F/ITGB6/CACNA2D3/ITGA4/ACTG1/DSC2/CACNG2/CACNG1/TCF7L1/SGCD	16
KEGG	hsa05410	Hypertrophic cardiomyopathy	18/972	90/8135	0.01855	0.1392	0.1176	CACNG3/ITGA7/PRKAA1/MYL3/DAG1/TNF/ATP2A1/ITGA3/CACNA1F/ITGB6/IGF1/CACNA2D3/ITGA4/ACTG1/CACNG2/CACNG1/PRKAB2/SGCD	18
KEGG	hsa05219	Bladder cancer	10/972	41/8135	0.01987	0.1457	0.1232	HBEGF/E2F2/DAPK3/RASSF1/SRC/E2F1/TYMP/EGFR/THBS1/RAF1	10
KEGG	hsa04750	Inflammatory mediator regulation of TRP channels	19/972	98/8135	0.02163	0.1519	0.1284	ALOX12/ADCY3/PRKCB/PTGER2/P2RY2/TRPV4/ITPR3/ITPR1/IGF1/SRC/IL1RAP/CALML3/HTR2B/MAP2K6/CAMK2G/CALML5/ADCY1/PRKCA/PRKCE	19
KEGG	hsa04925	Aldosterone synthesis and secretion	19/972	98/8135	0.02163	0.1519	0.1284	CAMK1D/ADCY3/PRKCB/CACNA1I/CREB3L2/ITPR3/CACNA1F/ITPR1/CYP11A1/CALML3/DAGLB/CAMK2G/CALML5/ADCY1/PRKCA/CACNA1H/PRKCE/KCNK3/AGTR1	19
KEGG	hsa04912	GnRH signaling pathway	18/972	93/8135	0.02534	0.1726	0.1459	ADCY3/MAP3K3/PRKCB/CDC42/HBEGF/ITPR3/CACNA1F/ITPR1/SRC/CALML3/JUN/MAP2K6/CAMK2G/CALML5/ADCY1/PRKCA/EGFR/RAF1	18
KEGG	hsa05310	Asthma	8/972	31/8135	0.02582	0.1726	0.1459	IL10/HLA-DPB1/TNF/MS4A2/FCER1A/HLA-DMB/IL4/HLA-DMA	8
KEGG	hsa05163	Human cytomegalovirus infection	37/972	225/8135	0.02616	0.1726	0.1459	HLA-B/CHUK/ADCY3/CCR1/PRKCB/CREB3L2/HLA-G/CRKL/PTGER2/TNF/HLA-C/IL10RA/E2F2/ITPR3/CCL5/FAS/ITPR1/CDK6/SRC/ROCK1/ARHGEF12/TNFRSF1A/GNB2/CALML3/GNG10/CCR5/NFATC3/PPP3R1/MAP2K6/E2F1/CALML5/ADCY1/PDIA3/PRKCA/EGFR/CX3CL1/RAF1	37
KEGG	hsa05143	African trypanosomiasis	9/972	37/8135	0.02695	0.1744	0.1474	HBB/MYD88/IL10/PRKCB/TNF/TLR9/FAS/HPR/PRKCA	9
KEGG	hsa04657	IL-17 signaling pathway	18/972	94/8135	0.02797	0.1775	0.15	HSP90B1/CXCL1/LCN2/S100A9/CHUK/HSP90AB1/TNFAIP3/IL17B/TNF/CXCL3/CXCL2/CXCL6/JUN/IL17RC/MUC5AC/CXCL5/IL4/MAP3K7	18
KEGG	hsa05205	Proteoglycans in cancer	34/972	205/8135	0.02866	0.1784	0.1508	TLR4/FZD5/TLR2/FZD1/CD63/PRKCB/TWIST2/CDC42/PDPK1/HBEGF/PPP1R12C/TNF/VAV3/ITPR3/FAS/ITPR1/WNT5B/IGF1/SRC/ROCK1/ARHGEF12/FLNA/ACTG1/HGF/SDC2/CAMK2G/FLNB/EIF4B/FZD6/PRKCA/PLAU/EGFR/THBS1/RAF1	34
KEGG	hsa04218	Cellular senescence	27/972	156/8135	0.0295	0.1803	0.1524	HLA-B/HLA-G/CDKN2B/ATR/HLA-C/E2F2/TRPV4/SLC25A5/ITPR3/ITPR1/CDK6/SQSTM1/CALML3/PPID/NFATC3/PPP3R1/MAP2K6/E2F1/FOXO1/CCND3/CALML5/LIN37/RASSF5/KIR2DL4/BTRC/RAF1/CCNB1	27
KEGG	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	17/972	89/8135	0.03279	0.1967	0.1663	TLR4/TLR2/CHUK/MYD88/MAP3K3/BATF3/BATF/JAK2/TLR9/NFKBIE/JUN/NFATC3/NFKBIB/PPP3R1/MAP2K6/EGFR/RAF1	17
KEGG	hsa05414	Dilated cardiomyopathy	18/972	96/8135	0.03384	0.1994	0.1686	CACNG3/ITGA7/ADCY3/MYL3/DAG1/TNF/ATP2A1/ITGA3/CACNA1F/ITGB6/IGF1/CACNA2D3/ITGA4/ACTG1/CACNG2/ADCY1/CACNG1/SGCD	18
KEGG	hsa00330	Arginine and proline metabolism	11/972	51/8135	0.03562	0.2062	0.1743	NOS3/ALDH18A1/MAOA/CKB/PRODH2/ARG2/SRM/SMOX/LAP3/ALDH4A1/ARG1	11
KEGG	hsa00480	Glutathione metabolism	12/972	58/8135	0.03884	0.221	0.1868	CHAC2/GGT5/GSTP1/ANPEP/SRM/GGT1/LAP3/GCLC/GSTT1/GPX7/MGST1/GSTO2	12
KEGG	hsa04020	Calcium signaling pathway	38/972	240/8135	0.04115	0.2302	0.1946	CAMK1D/ADCY3/NOS3/CYSLTR2/FGF6/EDNRB/PRKCB/CACNA1I/P2RX7/FGF22/ATP2A1/SLC25A5/ITPR3/PTAFR/CACNA1F/ITPR1/HTR7/FLT1/CALML3/RYR1/HGF/FGF3/HTR2B/VEGFC/HRH2/P2RX6/PPP3R1/CAMK2G/MST1R/CALML5/ADCY1/PRKCA/ASPH/CACNA1H/PTGFR/EGFR/P2RX2/AGTR1	38
KEGG	hsa04110	Cell cycle	22/972	126/8135	0.04238	0.2331	0.197	PRKDC/ANAPC13/BUB1/RBX1/CDKN2B/MCM7/ATR/CDKN1C/MAD2L1/YWHAH/E2F2/CDK6/ANAPC1/CDC14A/BUB3/CDKN1B/E2F1/CDC26/CCND3/CDC14B/CCNB1/EP300	22
KEGG	hsa05207	Chemical carcinogenesis - receptor activation	34/972	212/8135	0.04388	0.2362	0.1996	HSP90B1/NOTCH2/BCL6/ADCY3/KLF5/CYP1B1/FGF6/HSP90AB1/PRKCB/CREB3L2/JAK2/FGF22/EPHX1/ARNT/CACNA1F/SRC/BCL2/GSTT1/FGF3/EPHX3/RPS6KA3/JUN/KPNB1/CHRNA4/MGST1/E2F1/CCND3/ADCY1/PRKCA/EGFR/MIRLET7D/RAF1/GSTO2/DLL3	34
KEGG	hsa04934	Cushing syndrome	26/972	155/8135	0.04518	0.2362	0.1996	FZD5/ADCY3/FZD1/CACNA1I/CREB3L2/CDKN2B/E2F2/ITPR3/FH/ARNT/CACNA1F/ITPR1/CDK6/WNT5B/CYP11A1/APC/CDKN1B/CAMK2G/E2F1/FZD6/ADCY1/CACNA1H/EGFR/TCF7L1/KCNK3/AGTR1	26
KEGG	hsa04270	Vascular smooth muscle contraction	23/972	134/8135	0.04573	0.2362	0.1996	ADCY3/CALCRL/PRKCB/MYH9/PPP1R12C/ITPR3/CACNA1F/ITPR1/PLA2G2F/ROCK1/ARHGEF12/CALML3/EDN2/CALML5/ADCY1/PRKCA/EDN3/PRKCE/AVP/KCNMB4/RAF1/MYL6B/AGTR1	23
KEGG	hsa05320	Autoimmune thyroid disease	11/972	53/8135	0.0458	0.2362	0.1996	HLA-B/IL10/HLA-DPB1/HLA-G/HLA-C/FAS/CTLA4/GZMB/HLA-DMB/IL4/HLA-DMA	11
KEGG	hsa03060	Protein export	6/972	23/8135	0.0485	0.2462	0.2082	SEC62/SRP54/SEC11A/SRP19/SEC11C/SRPRB	6
KEGG	hsa05164	Influenza A	28/972	171/8135	0.05053	0.2527	0.2136	TLR4/CHUK/MYD88/PRKCB/HLA-DPB1/IRF9/TNF/JAK2/TNFRSF10A/NXF3/SLC25A5/CCL5/FAS/CDK6/IFNAR2/TNFRSF1A/ACTG1/SOCS3/RAB11A/NFKBIB/PABPN1/CCND3/HLA-DMB/PRKCA/IRAK4/HLA-DMA/RAF1/EP300	28
KEGG	hsa05332	Graft-versus-host disease	9/972	42/8135	0.05643	0.276	0.2333	HLA-B/HLA-DPB1/HLA-G/TNF/HLA-C/FAS/GZMB/HLA-DMB/HLA-DMA	9
KEGG	hsa05142	Chagas disease	18/972	102/8135	0.05687	0.276	0.2333	C1QB/C1QA/C1QC/TLR4/TLR2/C3/CHUK/MYD88/IL10/PPP2CB/TNF/TLR9/CCL5/FAS/TNFRSF1A/JUN/ADCY1/IRAK4	18
KEGG	hsa04310	Wnt signaling pathway	27/972	167/8135	0.0616	0.2917	0.2466	FZD5/LGR4/FZD1/PRKCB/TBL1Y/RBX1/SFRP4/GPC4/WNT5B/APC/NOTUM/JUN/NFATC3/PPP3R1/CAMK2G/CCND3/RSPO3/FZD6/NKD2/PRKCA/TLE6/LRP5/TCF7L1/RSPO1/MAP3K7/BTRC/EP300	27
KEGG	hsa04080	Neuroactive ligand-receptor interaction	52/972	353/8135	0.06188	0.2917	0.2466	FPR2/C3AR1/GHRL/C3/GPHA2/CHRNE/RLN3/MCHR1/CALCRL/CYSLTR2/EDNRB/VIPR1/FPR1/P2RX7/GALR3/PTGER2/THRA/INSL3/DRD4/PRL/P2RY2/TRH/GRP/PTAFR/GH2/C5AR1/SSTR1/HTR7/PARD3/GRM8/GALR2/HTR2B/HRH2/P2RX6/CHRNA4/NPW/GLRA2/SSTR2/P2RY8/EDN2/GRIK5/EDN3/APLN/PTGFR/AVP/GPR35/PTH2/RLN1/ADORA3/P2RX2/AGTR1/SSTR5	52
KEGG	hsa05165	Human papillomavirus infection	49/972	331/8135	0.06378	0.2964	0.2506	FZD5/NOTCH2/ATP6V1E1/HLA-B/COL9A2/SLC9A3R1/ITGA7/CHUK/HEYL/HES2/FZD1/CREB3L2/CDC42/PPP2CB/LAMC1/HLA-G/PPP2R3C/IRF9/ATR/TNF/HLA-C/ATP6V1C1/ITGA3/FAS/PPP2R5C/CDK6/ITGB6/WNT5B/IFNAR2/ATP6V1B1/ITGA4/TNFRSF1A/CRB3/PARD3/ATP6V1G3/APC/PSMC1/CDKN1B/LLGL2/E2F1/FOXO1/CCND3/TNR/FZD6/EGFR/TCF7L1/THBS1/RAF1/EP300	49
KEGG	hsa04371	Apelin signaling pathway	23/972	139/8135	0.06471	0.2966	0.2507	TFAM/ADCY3/NOS3/PRKAA1/MYL3/MEF2A/MYL4/ITPR3/MAP1LC3B2/ITPR1/GNB2/CALML3/RYR1/MAP1LC3A/GNG10/PPARGC1A/CALML5/ADCY1/APLN/PRKCE/PRKAB2/RAF1/AGTR1	23
KEGG	hsa04625	C-type lectin receptor signaling pathway	18/972	104/8135	0.06653	0.2967	0.2508	CLEC4D/CHUK/IL10/EGR2/IRF9/TNF/MAP3K14/ITPR3/ITPR1/SRC/ARHGEF12/CALML3/NFKB2/JUN/NFATC3/PPP3R1/CALML5/RAF1	18
KEGG	hsa04660	T cell receptor signaling pathway	18/972	104/8135	0.06653	0.2967	0.2508	CHUK/IL10/CDC42/PDPK1/TNF/MAP3K14/VAV3/NCK2/FYN/CTLA4/NFKBIE/JUN/NFATC3/NFKBIB/PPP3R1/IL4/MAP3K7/RAF1	18
KEGG	hsa04722	Neurotrophin signaling pathway	20/972	119/8135	0.07107	0.3086	0.2608	SORT1/SH2B3/MAP3K3/ARHGDIG/CDC42/CRKL/PDPK1/NTF3/BCL2/CALML3/MAP3K5/RPS6KA3/NFKBIE/JUN/MAGED1/NFKBIB/CAMK2G/CALML5/IRAK4/RAF1	20
KEGG	hsa04935	Growth hormone synthesis, secretion and action	20/972	119/8135	0.07107	0.3086	0.2608	GHRL/ADCY3/PRKCB/CREB3L2/CRKL/JAK2/ITPR3/GH2/CACNA1F/ITPR1/SSTR1/IGF1/SOCS3/MAP2K6/SSTR2/ADCY1/PRKCA/RAF1/EP300/SSTR5	20
KEGG	hsa04140	Autophagy - animal	23/972	141/8135	0.07365	0.3149	0.2662	SH3GLB1/RRAGA/PRKAA1/MTMR4/PPP2CB/CTSD/PDPK1/MAP1LC3B2/ITPR1/DAPK3/SQSTM1/RRAGD/BCL2/CAMKK2/ATG3/MAP1LC3A/BCL2L1/ATG16L1/MTMR14/SNAP29/RAB39B/MAP3K7/RAF1	23
KEGG	hsa04150	mTOR signaling pathway	25/972	156/8135	0.07606	0.3149	0.2662	FZD5/GRB10/ATP6V1E1/RRAGA/CHUK/FZD1/PRKAA1/PRKCB/PDPK1/TNF/SLC38A9/EIF4E2/ATP6V1C1/WNT5B/RRAGD/IGF1/ATP6V1B1/TNFRSF1A/ATP6V1G3/RPS6KA3/EIF4B/FZD6/PRKCA/LRP5/RAF1	25
KEGG	hsa04152	AMPK signaling pathway	20/972	120/8135	0.07616	0.3149	0.2662	ACACB/PRKAA1/ADIPOR2/PFKFB2/CREB3L2/PPP2CB/CPT1C/PDPK1/PPP2R3C/PPARG/PPP2R5C/IGF1/CAMKK2/EEF2/PPARGC1A/FOXO1/EEF2K/PFKM/PRKAB2/MAP3K7	20
KEGG	hsa04928	Parathyroid hormone synthesis, secretion and action	18/972	106/8135	0.07724	0.3149	0.2662	SLC9A3R1/ADCY3/MAFB/PRKCB/CREB3L2/MEF2A/HBEGF/ITPR3/KL/ITPR1/BCL2/CASR/MMP25/ADCY1/PRKCA/EGFR/LRP5/RAF1	18
KEGG	hsa04012	ErbB signaling pathway	15/972	85/8135	0.0773	0.3149	0.2662	AREG/PRKCB/NRG1/CRKL/HBEGF/NCK2/SRC/JUN/CDKN1B/CAMK2G/TGFA/PRKCA/EGFR/RAF1/NRG4	15
KEGG	hsa05321	Inflammatory bowel disease	12/972	65/8135	0.08143	0.3277	0.277	MAF/TLR4/TLR2/IL10/HLA-DPB1/IL2RG/TNF/JUN/NOD2/HLA-DMB/IL4/HLA-DMA	12
KEGG	hsa01521	EGFR tyrosine kinase inhibitor resistance	14/972	79/8135	0.08348	0.3319	0.2806	GAS6/PRKCB/NRG1/JAK2/EIF4E2/IGF1/SRC/BCL2/HGF/BCL2L1/TGFA/PRKCA/EGFR/RAF1	14
KEGG	hsa04210	Apoptosis	22/972	136/8135	0.08469	0.3327	0.2812	PMAIP1/CHUK/CTSD/PDPK1/TNF/TNFRSF10A/MAP3K14/BCL2A1/ITPR3/FAS/ITPR1/BCL2/TNFRSF1A/ACTG1/MAP3K5/LMNB1/GZMB/JUN/BCL2L1/SPTA1/PARP3/RAF1	22
KEGG	hsa04151	PI3K-Akt signaling pathway	51/972	354/8135	0.08705	0.3334	0.2818	AREG/HSP90B1/TLR4/TLR2/COL9A2/ITGA7/CHUK/NOS3/OSMR/FGF6/HSP90AB1/PRKAA1/CREB3L2/PPP2CB/LAMC1/PDPK1/PPP2R3C/IL2RG/JAK2/FGF22/EIF4E2/NTF3/PRL/YWHAH/ITGA3/GH2/PPP2R5C/CDK6/ITGB6/IFNAR2/IGF1/ITGA4/BCL2/FLT1/GNB2/HGF/FGF3/GNG10/VEGFC/BCL2L1/CDKN1B/CCND3/EIF4B/TNR/TGFA/PRKCA/CSF1R/EGFR/IL4/THBS1/RAF1	51
KEGG	hsa04810	Regulation of actin cytoskeleton	33/972	218/8135	0.08897	0.3334	0.2818	WASF1/ITGA7/WASF2/FGF6/MYH9/ARPC5L/CDC42/ACTR2/DIAPH1/CRKL/PPP1R12C/FGF22/VAV3/ITGA3/ITGB6/SCIN/SRC/ITGA4/MYL7/ROCK1/ARHGEF12/ACTG1/APC/ARPC5/FGF3/GSN/MYL10/MOS/EGFR/ARHGEF4/ARPC1A/RAF1/DOCK1	33
KEGG	hsa03013	Nucleocytoplasmic transport	18/972	108/8135	0.08904	0.3334	0.2818	IPO9/IPO5/SRRM1/NUP155/IPO7/NUP214/NUP210/UBE2I/TPR/NUP93/NXF3/NUP205/NUP210L/THOC1/POM121/THOC2/KPNB1/NUP107	18
KEGG	hsa04916	Melanogenesis	17/972	101/8135	0.0898	0.3334	0.2818	FZD5/ADCY3/FZD1/EDNRB/PRKCB/CREB3L2/WNT5B/CALML3/CAMK2G/FZD6/CALML5/ADCY1/PRKCA/MITF/TCF7L1/RAF1/EP300	17
KEGG	hsa01524	Platinum drug resistance	13/972	73/8135	0.0902	0.3334	0.2818	PMAIP1/MSH6/GSTP1/PDPK1/FAS/TOP2A/BCL2/MSH2/MAP3K5/GSTT1/BCL2L1/MGST1/GSTO2	13
KEGG	hsa04130	SNARE interactions in vesicular transport	7/972	33/8135	0.09092	0.3334	0.2818	STX8/STX2/STX4/GOSR1/YKT6/SNAP29/VAMP7	7
KEGG	hsa04066	HIF-1 signaling pathway	18/972	109/8135	0.09535	0.3455	0.2921	TLR4/NOS3/PRKCB/MKNK2/RBX1/EIF4E2/ARNT/LDHC/IGF1/BCL2/FLT1/PGK2/CDKN1B/CAMK2G/PRKCA/PFKM/EGFR/EP300	18
KEGG	hsa05416	Viral myocarditis	11/972	60/8135	0.09633	0.3455	0.2921	HLA-B/HLA-DPB1/HLA-G/DAG1/HLA-C/FYN/ACTG1/CD55/HLA-DMB/HLA-DMA/SGCD	11
KEGG	hsa04720	Long-term potentiation	12/972	67/8135	0.09753	0.3461	0.2925	PRKCB/ITPR3/ITPR1/CALML3/RPS6KA3/PPP3R1/CAMK2G/CALML5/ADCY1/PRKCA/RAF1/EP300	12
KEGG	hsa03040	Spliceosome	23/972	147/8135	0.1054	0.3619	0.3059	SF3B2/TRA2B/DDX42/U2AF1L4/TRA2A/LSM4/THOC1/SNRNP200/TCERG1/BCAS2/PHF5A/THOC2/HNRNPM/PRPF38B/SNRPA1/PCBP1/TXNL4A/AQR/U2AF2/LSM7/PPIH/SF3B5/RBM25	23
KEGG	hsa01230	Biosynthesis of amino acids	13/972	75/8135	0.1064	0.3619	0.3059	MAT2A/GLUL/TPI1/SHMT2/ALDH18A1/ARG2/CS/MAT1A/ARG1/PGK2/PFKM/RPIA/SDSL	13
KEGG	hsa03320	PPAR signaling pathway	13/972	75/8135	0.1064	0.3619	0.3059	ME1/GK/APOA5/CPT1C/PDPK1/ANGPTL4/PPARG/ACOX1/ACSL1/ACAA1/FABP5/SLC27A1/LPL	13
KEGG	hsa05214	Glioma	13/972	75/8135	0.1064	0.3619	0.3059	CAMK1D/PRKCB/E2F2/CDK6/IGF1/CALML3/CAMK2G/E2F1/TGFA/CALML5/PRKCA/EGFR/RAF1	13
KEGG	hsa04713	Circadian entrainment	16/972	97/8135	0.1119	0.376	0.3178	ADCY3/PRKCB/CACNA1I/ITPR3/ITPR1/GNB2/CALML3/RYR1/GNG10/PER3/CAMK2G/CALML5/ADCY1/PRKCA/CACNA1H/NOS1AP	16
KEGG	hsa05202	Transcriptional misregulation in cancer	29/972	193/8135	0.113	0.376	0.3178	MAF/FCGR1A/BCL6/CD14/SMAD1/HPGD/ETV7/ETV5/PPARG/JUP/MYCN/SS18L1/BCL2A1/CEBPA/IGF1/FLT1/NFKBIZ/CDK9/IL1R2/GZMB/BCL2L1/CDKN1B/FOXO1/PLAU/PROM1/CSF1R/MITF/RUNX1/DEFA4	29
KEGG	hsa00430	Taurine and hypotaurine metabolism	4/972	16/8135	0.1146	0.376	0.3178	GGT5/ADO/GGT1/FMO2	4
KEGG	hsa04971	Gastric acid secretion	13/972	76/8135	0.1151	0.376	0.3178	ADCY3/KCNJ15/PRKCB/ITPR3/ITPR1/ACTG1/CALML3/HRH2/SSTR2/CAMK2G/CALML5/ADCY1/PRKCA	13
KEGG	hsa05100	Bacterial invasion of epithelial cells	13/972	77/8135	0.1242	0.4018	0.3396	WASF1/WASF2/ARPC5L/CDC42/ACTR2/CRKL/SRC/ELMO2/ACTG1/ARPC5/ARHGAP10/ARPC1A/DOCK1	13
KEGG	hsa03010	Ribosome	24/972	158/8135	0.1276	0.4089	0.3456	RPS28/RPS27/RPLP1/RPS15A/RPL14/RPS27A/MRPL36/RPS29/RPL36A/RPS2/RPLP0/MRPL13/MRPL14/RPS26/RPL3L/RPS13/UBA52/RPL38/RPS3A/MRPL33/RPL12/RPL37/RPL10A/RPSA	24
KEGG	hsa04658	Th1 and Th2 cell differentiation	15/972	92/8135	0.13	0.4126	0.3487	MAF/NOTCH2/CHUK/HLA-DPB1/IL2RG/JAK2/NFKBIE/JUN/NFATC3/NFKBIB/PPP3R1/HLA-DMB/IL4/HLA-DMA/DLL3	15
KEGG	hsa04614	Renin-angiotensin system	5/972	23/8135	0.1314	0.4128	0.349	CTSA/ANPEP/CPA3/KLK2/AGTR1	5
KEGG	hsa04922	Glucagon signaling pathway	17/972	107/8135	0.1337	0.4128	0.349	ACACB/PRKAA1/CREB3L2/CPT1C/ITPR3/LDHC/ITPR1/CALML3/PPARGC1A/PPP3R1/CAMK2G/FOXO1/CALML5/PFKM/SIK2/PRKAB2/EP300	17
KEGG	hsa00071	Fatty acid degradation	8/972	43/8135	0.1342	0.4128	0.349	CYP2U1/ACADS/ACAT2/CPT1C/ACOX1/ACSL1/ACAA1/ADH1A	8
KEGG	hsa04933	AGE-RAGE signaling pathway in diabetic complications	16/972	100/8135	0.1364	0.4128	0.349	NOS3/THBD/PRKCB/CDC42/DIAPH1/TNF/JAK2/PIM1/BCL2/VEGFC/JUN/CDKN1B/FOXO1/PRKCA/PRKCE/AGTR1	16
KEGG	hsa00910	Nitrogen metabolism	4/972	17/8135	0.1364	0.4128	0.349	GLUL/CA1/CA4/CA12	4
KEGG	hsa04145	Phagosome	23/972	152/8135	0.1376	0.4128	0.349	FCGR1A/TLR4/TLR2/CD14/ATP6V1E1/C3/HLA-B/HLA-DPB1/STX12/HLA-G/MSR1/HLA-C/ATP6V1C1/ATP6V1B1/ACTG1/FCGR2C/ATP6V1G3/NCF4/FCGR2B/HLA-DMB/MARCO/THBS1/HLA-DMA	23
KEGG	hsa05225	Hepatocellular carcinoma	25/972	168/8135	0.1442	0.425	0.3593	FZD5/FZD1/PRKCB/GSTP1/E2F2/SMARCC1/CDK6/WNT5B/ACTG1/HGF/APC/GSTT1/ARID1A/BCL2L1/MGST1/E2F1/FZD6/TGFA/PRKCA/SMARCA2/EGFR/LRP5/TCF7L1/RAF1/GSTO2	25
KEGG	hsa04915	Estrogen signaling pathway	21/972	138/8135	0.1447	0.425	0.3593	HSP90B1/ADCY3/NOS3/HSP90AB1/CREB3L2/KRT32/CTSD/HBEGF/ITPR3/ITPR1/SRC/BCL2/CALML3/JUN/NCOA2/TGFA/CALML5/ADCY1/FKBP4/EGFR/RAF1	21
KEGG	hsa05223	Non-small cell lung cancer	12/972	72/8135	0.1455	0.425	0.3593	PRKCB/PDPK1/E2F2/CDK6/RASSF1/HGF/E2F1/TGFA/PRKCA/RASSF5/EGFR/RAF1	12
KEGG	hsa04927	Cortisol synthesis and secretion	11/972	65/8135	0.1472	0.426	0.3601	ADCY3/CACNA1I/CREB3L2/ITPR3/CACNA1F/ITPR1/CYP11A1/ADCY1/CACNA1H/KCNK3/AGTR1	11
KEGG	hsa00270	Cysteine and methionine metabolism	9/972	51/8135	0.1486	0.4264	0.3605	MAT2A/DNMT3A/AHCY/SRM/LDHC/MAT1A/DNMT3B/GCLC/SDSL	9
KEGG	hsa04062	Chemokine signaling pathway	28/972	192/8135	0.1524	0.4334	0.3664	CXCL1/CHUK/ADCY3/CCR1/PRKCB/CDC42/CCL21/CRKL/CXCL3/JAK2/VAV3/CCL5/CXCL2/SRC/ROCK1/XCR1/GNB2/PARD3/GNG10/CXCL6/CCR5/NFKBIB/ADCY1/CXCL5/CXCR1/CX3CL1/CCL8/RAF1	28
KEGG	hsa00061	Fatty acid biosynthesis	4/972	18/8135	0.1598	0.4506	0.3809	ACACB/ACSL1/OXSM/OLAH	4
KEGG	hsa04141	Protein processing in endoplasmic reticulum	25/972	171/8135	0.1655	0.4628	0.3912	STT3B/HSP90B1/HYOU1/HSP90AB1/SEC62/SEC31A/RBX1/HSPH1/HERPUD1/DDOST/SSR1/DNAJC10/BCL2/DNAJB2/MAP3K5/ERP29/UBE2D2/FBXO6/UBE2J1/UGGT2/PDIA3/DNAJC5G/EDEM1/MAN1C1/SEC24B	25
KEGG	hsa05221	Acute myeloid leukemia	11/972	67/8135	0.1708	0.4716	0.3987	FCGR1A/CD14/CHUK/JUP/BCL2A1/CEBPA/PIM1/CSF1R/TCF7L1/RUNX1/RAF1	11
KEGG	hsa04211	Longevity regulating pathway	14/972	89/8135	0.1715	0.4716	0.3987	ADCY3/PRKAA1/ADIPOR2/CREB3L2/EIF4E2/PPARG/KL/IGF1/CAMKK2/EHMT1/PPARGC1A/FOXO1/ADCY1/PRKAB2	14
KEGG	hsa00640	Propanoate metabolism	6/972	32/8135	0.1759	0.4793	0.4052	ACACB/ACADS/LDHC/ACOX1/BCKDHB/PCCB	6
KEGG	hsa03050	Proteasome	8/972	46/8135	0.1772	0.4793	0.4052	PSMD14/PSMB7/PSMD12/PSMA6/PSMC1/PSMB6/PSME4/PSMD1	8
KEGG	hsa04261	Adrenergic signaling in cardiomyocytes	22/972	150/8135	0.18	0.483	0.4083	CACNG3/ADCY3/CREB3L2/MYL3/PPP2CB/PPP2R3C/MYL4/ATP2A1/CACNA1F/PPP2R5C/CREM/CACNA2D3/BCL2/CALML3/CACNG2/SCN1B/CAMK2G/CALML5/ADCY1/PRKCA/CACNG1/AGTR1	22
KEGG	hsa04664	Fc epsilon RI signaling pathway	11/972	68/8135	0.1832	0.4876	0.4121	INPP5D/PDPK1/TNF/VAV3/FYN/MS4A2/FCER1A/MAP2K6/PRKCA/IL4/RAF1	11
KEGG	hsa04144	Endocytosis	35/972	251/8135	0.1849	0.4882	0.4127	AMPH/WIPF1/SH3GLB1/HLA-B/RAB11FIP5/CHMP6/ARF1/ARPC5L/STAM2/CDC42/ACTR2/ASAP1/DAB2/HLA-G/IL2RG/AGAP5/ARF3/HLA-C/VPS37A/SRC/SNX2/PARD3/EHD2/ARPC5/RAB11A/CCR5/CHMP2A/RAB11FIP1/CXCR1/IQSEC2/EGFR/ARPC1A/SNX6/TSG101/RAB11FIP4	35
KEGG	hsa00590	Arachidonic acid metabolism	10/972	61/8135	0.1868	0.4886	0.413	AKR1C3/ALOX12/GGT5/CYP4F2/CYP2U1/LTC4S/PLA2G2F/GGT1/GPX7/CYP4F8	10
KEGG	hsa04725	Cholinergic synapse	17/972	113/8135	0.1881	0.4886	0.413	ADCY3/PRKCB/CREB3L2/JAK2/ITPR3/FYN/CACNA1F/ITPR1/BCL2/SLC18A3/GNB2/GNG10/CHRNA4/CAMK2G/ADCY1/PRKCA/KCNQ2	17
KEGG	hsa04022	cGMP-PKG signaling pathway	24/972	167/8135	0.194	0.4952	0.4186	ADCY3/NOS3/EDNRB/CREB3L2/MEF2A/RGS2/ATP2A1/SLC25A5/ITPR3/CACNA1F/ITPR1/ROCK1/CALML3/NFATC3/PPP3R1/GTF2I/CALML5/ADCY1/PRKCE/KCNMB4/ADORA3/CNGB1/RAF1/AGTR1	24
KEGG	hsa00051	Fructose and mannose metabolism	6/972	33/8135	0.1948	0.4952	0.4186	TPI1/ENOSF1/PFKFB2/AKR1B1/KHK/PFKM	6
KEGG	hsa05031	Amphetamine addiction	11/972	69/8135	0.1961	0.4952	0.4186	SLC18A1/PRKCB/CREB3L2/MAOA/CALML3/JUN/PPP3R1/ARC/CAMK2G/CALML5/PRKCA	11
KEGG	hsa03450	Non-homologous end-joining	3/972	13/8135	0.1966	0.4952	0.4186	LIG4/XRCC4/PRKDC	3
KEGG	hsa00670	One carbon pool by folate	4/972	20/8135	0.2102	0.523	0.4421	DHFR/SHMT2/MTHFD1/MTHFS	4
KEGG	hsa04966	Collecting duct acid secretion	5/972	27/8135	0.2144	0.523	0.4421	ATP6V1E1/ATP6V1C1/ATP6V1B1/ATP6V1G3/SLC4A1	5
KEGG	hsa04931	Insulin resistance	16/972	108/8135	0.2146	0.523	0.4421	NOS3/ACACB/PRKAA1/PRKCB/CREB3L2/PDPK1/TNF/MLX/TNFRSF1A/SOCS3/RPS6KA3/SLC27A1/PPARGC1A/FOXO1/PRKCE/PRKAB2	16
KEGG	hsa04612	Antigen processing and presentation	12/972	78/8135	0.2166	0.523	0.4421	HLA-B/HSP90AB1/HLA-DPB1/HLA-G/TNF/HLA-C/HSPA4/HLA-DMB/PDIA3/KIR2DL4/HLA-DMA/CD74	12
KEGG	hsa04721	Synaptic vesicle cycle	12/972	78/8135	0.2166	0.523	0.4421	ATP6V1E1/SLC18A1/SLC1A3/SLC6A9/ATP6V1C1/SLC6A7/ATP6V1B1/SLC18A3/STX2/ATP6V1G3/SLC6A5/NAPA	12
KEGG	hsa04630	JAK-STAT signaling pathway	23/972	162/8135	0.2172	0.523	0.4421	SOCS7/IL10/OSMR/STAM2/IL2RG/IRF9/JAK2/IL10RA/PRL/GH2/CNTFR/IFNAR2/PIM1/BCL2/SOCS3/IFNW1/BCL2L1/THPO/CCND3/EGFR/IL4/RAF1/EP300	23
KEGG	hsa05162	Measles	20/972	139/8135	0.2187	0.523	0.4421	TLR4/TLR2/CHUK/MYD88/TNFAIP3/IL2RG/IRF9/TLR9/FAS/CDK6/IFNAR2/BCL2/JUN/BCL2L1/NFKBIB/FCGR2B/CDKN1B/CCND3/IRAK4/MAP3K7	20
KEGG	hsa05224	Breast cancer	21/972	147/8135	0.2215	0.5255	0.4442	FZD5/NOTCH2/HEYL/FGF6/FZD1/FGF22/E2F2/CDK6/WNT5B/IGF1/APC/NFKB2/FGF3/JUN/E2F1/FZD6/EGFR/LRP5/TCF7L1/RAF1/DLL3	21
KEGG	hsa04520	Adherens junction	11/972	71/8135	0.2229	0.5255	0.4442	WASF1/WASF2/CDC42/FYN/SRC/ACTG1/PARD3/EGFR/TCF7L1/MAP3K7/EP300	11
KEGG	hsa04672	Intestinal immune network for IgA production	8/972	49/8135	0.2255	0.5277	0.4461	TNFRSF13C/IL10/HLA-DPB1/MAP3K14/ITGA4/HLA-DMB/IL4/HLA-DMA	8
KEGG	hsa04015	Rap1 signaling pathway	29/972	210/8135	0.2276	0.529	0.4471	ADCY3/FGF6/PRKCB/FPR1/CDC42/CRKL/FGF22/TLN1/VAV3/APBB1IP/IGF1/SRC/FLT1/ACTG1/PARD3/CALML3/HGF/FGF3/VEGFC/MAP2K6/RALA/CALML5/ADCY1/PRKCA/RASSF5/CSF1R/EGFR/THBS1/RAF1	29
KEGG	hsa04137	Mitophagy - animal	11/972	72/8135	0.2369	0.5428	0.4589	CITED2/RPS27A/MAP1LC3B2/SQSTM1/SRC/MAP1LC3A/JUN/BCL2L1/E2F1/UBA52/MITF	11
KEGG	hsa05218	Melanoma	11/972	72/8135	0.2369	0.5428	0.4589	FGF6/FGF22/E2F2/CDK6/IGF1/HGF/FGF3/E2F1/EGFR/MITF/RAF1	11
KEGG	hsa04979	Cholesterol metabolism	8/972	50/8135	0.2426	0.5482	0.4634	SORT1/MYLIP/ANGPTL4/LIPA/LRPAP1/APOA4/LPL/OSBPL5	8
KEGG	hsa05110	Vibrio cholerae infection	8/972	50/8135	0.2426	0.5482	0.4634	ATP6V1E1/ADCY3/ARF1/ATP6V1C1/ATP6V1B1/ACTG1/ATP6V1G3/PRKCA	8
KEGG	hsa04115	p53 signaling pathway	11/972	73/8135	0.2511	0.5638	0.4766	PMAIP1/ATR/TNFRSF10A/FAS/CDK6/IGF1/BCL2/BCL2L1/CCND3/THBS1/CCNB1	11
KEGG	hsa00220	Arginine biosynthesis	4/972	22/8135	0.2644	0.5881	0.4971	GLUL/NOS3/ARG2/ARG1	4
KEGG	hsa04070	Phosphatidylinositol signaling system	14/972	97/8135	0.2655	0.5881	0.4971	DGKG/PRKCB/MTMR4/INPP5D/DGKE/ITPR3/ITPR1/PPIP5K1/CALML3/CALML5/PIK3C2B/PRKCA/MTMR7/MTMR14	14
KEGG	hsa04962	Vasopressin-regulated water reabsorption	7/972	44/8135	0.2683	0.5902	0.4989	ADCY3/ARHGDIG/CREB3L2/DCTN6/RAB11A/STX4/AVP	7
KEGG	hsa00250	Alanine, aspartate and glutamate metabolism	6/972	37/8135	0.2766	0.6045	0.511	GLUL/PPAT/ALDH4A1/NIT2/ALDH5A1/NAT8L	6
KEGG	hsa01522	Endocrine resistance	14/972	98/8135	0.2784	0.6045	0.511	NOTCH2/ADCY3/HBEGF/E2F2/IGF1/SRC/BCL2/JUN/CDKN1B/E2F1/ADCY1/EGFR/RAF1/DLL3	14
KEGG	hsa00630	Glyoxylate and dicarboxylate metabolism	5/972	30/8135	0.2849	0.6105	0.5161	GLUL/SHMT2/ACAT2/CS/PCCB	5
KEGG	hsa01523	Antifolate resistance	5/972	30/8135	0.2849	0.6105	0.5161	ALOX12/CHUK/DHFR/SHMT2/TNF	5
KEGG	hsa05161	Hepatitis B	22/972	162/8135	0.2926	0.6229	0.5265	TLR4/TLR2/CHUK/MYD88/PRKCB/CREB3L2/EGR2/TNF/JAK2/E2F2/FAS/SRC/BCL2/JUN/NFATC3/MAP2K6/E2F1/PRKCA/IRAK4/MAP3K7/RAF1/EP300	22
KEGG	hsa05212	Pancreatic cancer	11/972	76/8135	0.2956	0.6254	0.5286	CHUK/CDC42/E2F2/RAD51/CDK6/BCL2L1/RALA/E2F1/TGFA/EGFR/RAF1	11
KEGG	hsa04068	FoxO signaling pathway	18/972	131/8135	0.2993	0.6291	0.5317	BCL6/CHUK/IL10/PRKAA1/FBXO25/PDPK1/CDKN2B/HOMER3/IGF1/CDKN1B/FOXO1/PLK2/USP7/PRKAB2/EGFR/RAF1/CCNB1/EP300	18
KEGG	hsa05014	Amyotrophic lateral sclerosis	47/972	364/8135	0.3045	0.6295	0.5321	PSMD14/DNAH17/CHCHD10/NUP155/PSMB7/NDUFB9/NRG1/NUP214/NUP210/TPR/COX6B2/NEFH/PSMD12/TNF/PSMA6/NUP93/NXF3/ITPR3/MAP1LC3B2/NUP205/NUP210L/POM121/ACTR10/SQSTM1/DCTN6/BCL2/TNFRSF1A/ACTG1/MAP1LC3A/MAP3K5/DNAL1/NDUFA4L2/ACTR1A/BCL2L1/GPX7/PPP3R1/MAP2K6/PSMC1/KLC3/PSMB6/DNAH10/ACTR1B/RAB39B/NUP107/PSMD1/NRG4/DNAL4	47
KEGG	hsa04659	Th17 cell differentiation	15/972	108/8135	0.3068	0.6295	0.5321	CHUK/HSP90AB1/HLA-DPB1/IL2RG/JAK2/IL1RAP/NFKBIE/JUN/NFATC3/NFKBIB/PPP3R1/HLA-DMB/IL4/HLA-DMA/RUNX1	15
KEGG	hsa04924	Renin secretion	10/972	69/8135	0.3071	0.6295	0.5321	PTGER2/ITPR3/CACNA1F/ITPR1/CALML3/PPP3R1/EDN2/CALML5/EDN3/AGTR1	10
KEGG	hsa05211	Renal cell carcinoma	10/972	69/8135	0.3071	0.6295	0.5321	CDC42/CRKL/RBX1/FH/ARNT/HGF/JUN/TGFA/RAF1/EP300	10
KEGG	hsa04710	Circadian rhythm	5/972	31/8135	0.3094	0.6302	0.5327	PRKAA1/RBX1/PER3/PRKAB2/BTRC	5
KEGG	hsa01232	Nucleotide metabolism	12/972	85/8135	0.3139	0.6356	0.5373	IMPDH2/AMPD2/XDH/DGUOK/ENPP3/ENTPD4/ENTPD5/ENTPD2/DUT/TYMP/UPP2/CMPK2	12
KEGG	hsa04977	Vitamin digestion and absorption	4/972	24/8135	0.3208	0.6455	0.5456	TCN2/APOA4/LMBRD1/BTD	4
KEGG	hsa05226	Gastric cancer	20/972	149/8135	0.3236	0.6472	0.5471	FZD5/MUC2/FGF6/FZD1/CDKN2B/FGF22/JUP/E2F2/WNT5B/BCL2/HGF/APC/FGF3/CDKN1B/E2F1/FZD6/EGFR/LRP5/TCF7L1/RAF1	20
KEGG	hsa00620	Pyruvate metabolism	7/972	47/8135	0.3278	0.6495	0.549	AKR1A1/ME1/ACACB/ACAT2/FH/LDHC/ADH1A	7
KEGG	hsa05210	Colorectal cancer	12/972	86/8135	0.3287	0.6495	0.549	AREG/PMAIP1/MSH6/BCL2/MSH2/APC/JUN/RALA/TGFA/EGFR/TCF7L1/RAF1	12
KEGG	hsa04914	Progesterone-mediated oocyte maturation	14/972	102/8135	0.3319	0.6519	0.551	ADCY3/ANAPC13/HSP90AB1/BUB1/SPDYE1/MAD2L1/IGF1/ANAPC1/RPS6KA3/CDC26/MOS/ADCY1/RAF1/CCNB1	14
KEGG	hsa04215	Apoptosis - multiple species	5/972	32/8135	0.3341	0.6523	0.5514	PMAIP1/BCL2/TNFRSF1A/BIRC7/BCL2L1	5
KEGG	hsa00260	Glycine, serine and threonine metabolism	6/972	40/8135	0.3425	0.6648	0.5619	SHMT2/MAOA/CHDH/ALAS2/SARDH/SDSL	6
KEGG	hsa00280	Valine, leucine and isoleucine degradation	7/972	48/8135	0.3481	0.6717	0.5678	ACADS/ACAT2/BCKDHB/MCCC1/ACAA1/PCCB/HIBADH	7
KEGG	hsa03410	Base excision repair	5/972	33/8135	0.3589	0.6856	0.5795	POLE3/NEIL2/APEX1/POLD2/PARP3	5
KEGG	hsa04620	Toll-like receptor signaling pathway	14/972	104/8135	0.3594	0.6856	0.5795	TLR4/TLR2/CD14/CHUK/MYD88/TOLLIP/TNF/TLR9/CCL5/IFNAR2/JUN/MAP2K6/IRAK4/MAP3K7	14
KEGG	hsa04919	Thyroid hormone signaling pathway	16/972	121/8135	0.3722	0.706	0.5967	NOTCH2/PFKFB2/PRKCB/PDPK1/THRA/ATP2A1/SRC/ACTG1/DIO3/NCOA2/MED16/FOXO1/PRKCA/PFKM/RAF1/EP300	16
KEGG	hsa00790	Folate biosynthesis	4/972	26/8135	0.3779	0.7126	0.6024	AKR1C3/DHFR/AKR1B1/ALPI	4
KEGG	hsa04670	Leukocyte transendothelial migration	15/972	114/8135	0.3863	0.7243	0.6123	PRKCB/CDC42/CLDN17/VAV3/ITGA4/MYL7/ROCK1/CLDN3/ACTG1/NCF4/MYL10/CLDN10/PRKCA/RASSF5/TXK	15
KEGG	hsa00240	Pyrimidine metabolism	8/972	58/8135	0.3899	0.7269	0.6144	ENPP3/ENTPD4/ENTPD5/DUT/TYMP/UPP2/CMPK2/DPYS	8
KEGG	hsa05203	Viral carcinogenesis	26/972	204/8135	0.3933	0.7292	0.6164	C3/HLA-B/PMAIP1/HDAC8/CREB3L2/CDC42/EGR2/HLA-G/SND1/CDKN2B/IRF9/HLA-C/YWHAH/CDK6/SCIN/SRC/GTF2H3/NFKB2/GSN/CCR5/JUN/PSMC1/CDKN1B/CCND3/USP7/EP300	26
KEGG	hsa04060	Cytokine-cytokine receptor interaction	37/972	295/8135	0.4016	0.7403	0.6258	CXCL1/TNFRSF13C/IL10/OSMR/CCR1/GDF9/CCL21/IL17B/IL2RG/TNF/CXCL3/TNFRSF10A/IL10RA/PRL/CCL5/FAS/GH2/CNTFR/TNFRSF18/CXCL2/IFNAR2/XCR1/TNFRSF1A/IL1RAP/IL1R2/CXCL6/CCR5/IFNW1/INHBA/IL17RC/THPO/CXCL5/CXCR1/CSF1R/IL4/CX3CL1/CCL8	37
KEGG	hsa05222	Small cell lung cancer	12/972	92/8135	0.4195	0.7691	0.6501	CHUK/LAMC1/CDKN2B/E2F2/ITGA3/CDK6/BCL2/CKS2/BIRC7/BCL2L1/CDKN1B/E2F1	12
KEGG	hsa04014	Ras signaling pathway	29/972	232/8135	0.427	0.7709	0.6516	RGL1/CHUK/FGF6/PRKCB/CDC42/PLA1A/FGF22/NTF3/PLA2G2F/RASSF1/IGF1/HTR7/FLT1/GNB2/CALML3/HGF/FGF3/GNG10/VEGFC/SYNGAP1/BCL2L1/RALA/TGFA/CALML5/PRKCA/RASSF5/CSF1R/EGFR/RAF1	29
KEGG	hsa04730	Long-term depression	8/972	60/8135	0.4279	0.7709	0.6516	PRKCB/PPP2CB/ITPR3/ITPR1/IGF1/RYR1/PRKCA/RAF1	8
KEGG	hsa00600	Sphingolipid metabolism	7/972	52/8135	0.43	0.7709	0.6516	NEU4/SGMS1/GALC/SGPP2/ACER1/SGMS2/GAL3ST1	7
KEGG	hsa04120	Ubiquitin mediated proteolysis	18/972	142/8135	0.4323	0.7709	0.6516	HUWE1/UBE2E3/ANAPC13/UBE2I/RBX1/RPS27A/UBE2F/ANAPC1/SOCS3/RNF7/UBE2A/BIRC7/UBE2D2/HERC1/UBE2J1/CDC26/UBA52/BTRC	18
KEGG	hsa00760	Nicotinate and nicotinamide metabolism	5/972	36/8135	0.4335	0.7709	0.6516	QPRT/NNMT/NMNAT3/ENPP3/SIRT2	5
KEGG	hsa00650	Butanoate metabolism	4/972	28/8135	0.4345	0.7709	0.6516	ACADS/ACAT2/ALDH5A1/ACSM3	4
KEGG	hsa04217	Necroptosis	20/972	159/8135	0.4389	0.7746	0.6548	TLR4/CHMP6/GLUL/HSP90AB1/TNFAIP3/IRF9/TNF/JAK2/TNFRSF10A/SLC25A5/FAS/IFNAR2/SQSTM1/FAF1/BCL2/TNFRSF1A/PPID/CHMP2A/CAMK2G/RBCK1	20
KEGG	hsa00140	Steroid hormone biosynthesis	8/972	61/8135	0.4469	0.7803	0.6596	AKR1C3/CYP1B1/CYP11A1/STS/AKR1C2/DHRS11/SRD5A3/HSD17B3	8
KEGG	hsa00561	Glycerolipid metabolism	8/972	61/8135	0.4469	0.7803	0.6596	AKR1A1/DGKG/GK/GPAM/AKR1B1/DGKE/MBOAT2/LPL	8
KEGG	hsa05022	Pathways of neurodegeneration - multiple diseases	58/972	476/8135	0.4573	0.7913	0.6689	FZD5/PSMD14/DNAH17/FZD1/PRKCB/PSMB7/NDUFB9/COX6B2/NEFH/PSMD12/TNF/PSMA6/RPS27A/TRAP1/ATP2A1/SLC25A5/ITPR3/MAP1LC3B2/FAS/CACNA1F/ITPR1/ACTR10/WNT5B/SQSTM1/DCTN6/BCL2/TNFRSF1A/CALML3/RYR1/MAP1LC3A/MAP3K5/APC/DNAL1/PPID/NDUFA4L2/ACTR1A/BCL2L1/GPX7/PPP3R1/MAP2K6/PSMC1/UBE2J1/CAMK2G/KLC3/UBA52/CDK5R1/FZD6/PSMB6/CALML5/PRKCA/DNAH10/ACTR1B/RAB39B/LRP5/PSMD1/RAF1/SPTBN2/DNAL4	58
KEGG	hsa04960	Aldosterone-regulated sodium reabsorption	5/972	37/8135	0.458	0.7913	0.6689	PRKCB/SCNN1B/PDPK1/IGF1/PRKCA	5
KEGG	hsa04744	Phototransduction	4/972	29/8135	0.4623	0.7946	0.6716	CALML3/CALML5/GNAT1/CNGB1	4
KEGG	hsa00770	Pantothenate and CoA biosynthesis	3/972	21/8135	0.4669	0.7984	0.6748	VNN1/ENPP3/DPYS	3
KEGG	hsa04926	Relaxin signaling pathway	16/972	129/8135	0.4771	0.8115	0.686	RLN3/ADCY3/NOS3/EDNRB/CREB3L2/INSL3/SRC/GNB2/GNG10/VEGFC/JUN/ADCY1/PRKCA/EGFR/RLN1/RAF1	16
KEGG	hsa04512	ECM-receptor interaction	11/972	88/8135	0.4854	0.8214	0.6943	COL9A2/ITGA7/GP6/LAMC1/DAG1/GP1BB/ITGA3/ITGB6/ITGA4/TNR/THBS1	11
KEGG	hsa00983	Drug metabolism - other enzymes	10/972	80/8135	0.4907	0.8261	0.6983	GSTP1/IMPDH2/XDH/GSTT1/MGST1/DUT/TYMP/GSTO2/UPP2/DPYS	10
KEGG	hsa00900	Terpenoid backbone biosynthesis	3/972	22/8135	0.4989	0.83	0.7016	ACAT2/MVK/PCYOX1	3
KEGG	hsa04724	Glutamatergic synapse	14/972	114/8135	0.4996	0.83	0.7016	ADCY3/GLUL/PRKCB/SLC1A3/ITPR3/HOMER3/ITPR1/GNB2/GRM8/GNG10/PPP3R1/GRIK5/ADCY1/PRKCA	14
KEGG	hsa04727	GABAergic synapse	11/972	89/8135	0.5011	0.83	0.7016	ADCY3/GLUL/PRKCB/CACNA1F/SRC/GNB2/GNG10/SLC12A5/PLCL1/ADCY1/PRKCA	11
KEGG	hsa04929	GnRH secretion	8/972	64/8135	0.5031	0.83	0.7016	PRKCB/CACNA1I/ITPR3/CACNA1F/ITPR1/PRKCA/CACNA1H/RAF1	8
KEGG	hsa01200	Carbon metabolism	14/972	115/8135	0.5134	0.8344	0.7053	ME1/TPI1/SHMT2/ACADS/ACAT2/FH/ACOX1/CS/PGK2/PFKM/PCCB/RPIA/SDSL/OGDHL	14
KEGG	hsa04726	Serotonergic synapse	14/972	115/8135	0.5134	0.8344	0.7053	SLC18A1/ALOX12/PRKCB/MAOA/ITPR3/CACNA1F/ITPR1/HTR7/GNB2/GNG10/HTR2B/HTR3C/PRKCA/RAF1	14
KEGG	hsa04728	Dopaminergic synapse	16/972	132/8135	0.516	0.8344	0.7053	SLC18A1/PRKCB/CREB3L2/PPP2CB/PPP2R3C/MAOA/DRD4/ITPR3/ITPR1/PPP2R5C/GNB2/CALML3/GNG10/CAMK2G/CALML5/PRKCA	16
KEGG	hsa00410	beta-Alanine metabolism	4/972	31/8135	0.5163	0.8344	0.7053	ACADS/SMOX/ACOX1/DPYS	4
KEGG	hsa04514	Cell adhesion molecules	18/972	149/8135	0.5183	0.8344	0.7053	HLA-B/PDCD1LG2/HLA-DPB1/HLA-G/CLDN17/HLA-C/ITGA4/CADM1/CLDN3/CTLA4/CD58/NEO1/SDC2/CLDN10/ALCAM/HLA-DMB/NLGN2/HLA-DMA	18
KEGG	hsa00515	Mannose type O-glycan biosynthesis	3/972	23/8135	0.5299	0.8409	0.7108	B3GALNT2/POMT2/FKTN	3
KEGG	hsa03430	Mismatch repair	3/972	23/8135	0.5299	0.8409	0.7108	MSH6/MSH2/POLD2	3
KEGG	hsa01212	Fatty acid metabolism	7/972	57/8135	0.53	0.8409	0.7108	ACADS/ACAT2/CPT1C/ACOX1/ACSL1/ACAA1/OXSM	7
KEGG	hsa00520	Amino sugar and nucleotide sugar metabolism	6/972	49/8135	0.5401	0.8528	0.7208	NPL/CYB5R4/CHIT1/CMAS/CYB5R3/NANS	6
KEGG	hsa04918	Thyroid hormone synthesis	9/972	75/8135	0.5479	0.8611	0.7278	HSP90B1/ADCY3/PRKCB/CREB3L2/ITPR3/ITPR1/GPX7/ADCY1/PRKCA	9
KEGG	hsa04216	Ferroptosis	5/972	41/8135	0.5522	0.8637	0.7301	MAP1LC3B2/MAP1LC3A/GCLC/ACSL1/PCBP1	5
KEGG	hsa04970	Salivary secretion	11/972	93/8135	0.5626	0.8748	0.7394	ADCY3/PRKCB/ITPR3/ITPR1/CAMP/CALML3/PRB1/CALML5/ADCY1/PRKCA/CST2	11
KEGG	hsa05220	Chronic myeloid leukemia	9/972	76/8135	0.5646	0.8748	0.7394	CHUK/CRKL/E2F2/CDK6/BCL2L1/CDKN1B/E2F1/RUNX1/RAF1	9
KEGG	hsa04370	VEGF signaling pathway	7/972	59/8135	0.5681	0.8761	0.7406	NOS3/PRKCB/CDC42/SRC/PPP3R1/PRKCA/RAF1	7
KEGG	hsa04350	TGF-beta signaling pathway	11/972	94/8135	0.5775	0.8864	0.7492	RGMA/SMAD1/PPP2CB/RBX1/CDKN2B/TNF/ROCK1/INHBA/NEO1/THBS1/EP300	11
KEGG	hsa04913	Ovarian steroidogenesis	6/972	51/8135	0.5808	0.8874	0.7501	AKR1C3/ADCY3/CYP1B1/IGF1/CYP11A1/ADCY1	6
KEGG	hsa00592	alpha-Linolenic acid metabolism	3/972	25/8135	0.5884	0.8948	0.7564	PLA2G2F/ACOX1/ACAA1	3
KEGG	hsa04613	Neutrophil extracellular trap formation	22/972	190/8135	0.5972	0.9041	0.7642	FCGR1A/FPR2/TLR4/TLR2/CASP4/C3/HAT1/CR1L/HDAC8/PRKCB/FPR1/AQP9/SLC25A5/C5AR1/CAMP/SRC/ACTG1/CR1/NCF4/PRKCA/MAP3K7/RAF1	22
KEGG	hsa04260	Cardiac muscle contraction	10/972	87/8135	0.602	0.9065	0.7663	CACNG3/MYL3/COX6B2/MYL4/ATP2A1/CACNA1F/CACNA2D3/CACNG2/ASPH/CACNG1	10
KEGG	hsa04072	Phospholipase D signaling pathway	17/972	148/8135	0.6078	0.9065	0.7663	DGKG/ADCY3/ARF1/DGKE/FYN/MS4A2/GRM8/FCER1A/RALA/ADCY1/CXCR1/PRKCA/PTGFR/AVP/EGFR/RAF1/AGTR1	17
KEGG	hsa04650	Natural killer cell mediated cytotoxicity	15/972	131/8135	0.6111	0.9065	0.7663	HLA-B/PRKCB/HLA-G/TNF/HLA-C/TNFRSF10A/VAV3/FYN/FAS/IFNAR2/GZMB/PPP3R1/SH2D1B/PRKCA/RAF1	15
KEGG	hsa04390	Hippo signaling pathway	18/972	157/8135	0.6121	0.9065	0.7663	AREG/FZD5/FZD1/SMAD1/PPP2CB/YWHAH/WNT5B/RASSF1/ACTG1/PARD3/APC/LLGL2/CCND3/FZD6/WWC1/NKD2/TCF7L1/BTRC	18
KEGG	hsa03018	RNA degradation	9/972	79/8135	0.613	0.9065	0.7663	EXOSC3/LSM4/PABPC4/EDC4/PFKM/CNOT6L/DDX6/LSM7/PNPT1	9
KEGG	hsa04540	Gap junction	10/972	88/8135	0.617	0.9065	0.7663	ADCY3/PRKCB/ITPR3/ITPR1/SRC/HTR2B/ADCY1/PRKCA/EGFR/RAF1	10
KEGG	hsa00120	Primary bile acid biosynthesis	2/972	17/8135	0.6201	0.9065	0.7663	CH25H/HSD3B7	2
KEGG	hsa03015	mRNA surveillance pathway	11/972	97/8135	0.6208	0.9065	0.7663	PELO/SRRM1/CPSF7/PPP2CB/PPP2R3C/NXF3/PPP2R5C/PABPC4/GSPT1/PABPN1/PCF11	11
KEGG	hsa04611	Platelet activation	14/972	124/8135	0.6318	0.9133	0.772	ADCY3/GP6/NOS3/TLN1/GP1BB/ITPR3/FYN/APBB1IP/ITPR1/SRC/ROCK1/ARHGEF12/ACTG1/ADCY1	14
KEGG	hsa05231	Choline metabolism in cancer	11/972	98/8135	0.6348	0.9133	0.772	WASF1/DGKG/WASF2/PRKCB/PDPK1/DGKE/JUN/PRKCA/EGFR/RAF1/CHKA	11
KEGG	hsa03030	DNA replication	4/972	36/8135	0.6386	0.9133	0.772	RNASEH1/POLE3/MCM7/POLD2	4
KEGG	hsa00310	Lysine degradation	7/972	63/8135	0.6397	0.9133	0.772	ACAT2/EZH1/PRDM6/EHMT1/SETD2/PRDM2/EZH2	7
KEGG	hsa03250	Viral life cycle - HIV-1	7/972	63/8135	0.6397	0.9133	0.772	CHMP6/CPSF7/APOBEC3A/CDK9/CCR5/TSG101/EP300	7
KEGG	hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	3/972	27/8135	0.6421	0.9133	0.772	B3GNT3/B4GALT4/FUT5	3
KEGG	hsa05017	Spinocerebellar ataxia	16/972	143/8135	0.65	0.9193	0.7771	PSMD14/PRKCB/PSMB7/PSMD12/PSMA6/ATP2A1/SLC25A5/ITPR3/ITPR1/RYR1/MAP3K5/PSMC1/PSMB6/PRKCA/PSMD1/SPTBN2	16
KEGG	hsa00511	Other glycan degradation	2/972	18/8135	0.6518	0.9193	0.7771	NEU4/ENGASE	2
KEGG	hsa05216	Thyroid cancer	4/972	37/8135	0.6604	0.9274	0.7839	TPR/PPARG/TFG/TCF7L1	4
KEGG	hsa00531	Glycosaminoglycan degradation	2/972	19/8135	0.6814	0.9528	0.8054	SPAM1/HYAL4	2
KEGG	hsa04972	Pancreatic secretion	11/972	102/8135	0.6877	0.9575	0.8094	ADCY3/PRKCB/ATP2A1/ITPR3/ITPR1/PLA2G2F/CPA3/RAB11A/ADCY1/PRKCA/CELA3B	11
KEGG	hsa04392	Hippo signaling pathway - multiple species	3/972	29/8135	0.6906	0.9575	0.8094	RASSF1/WWC1/DCHS1	3
KEGG	hsa00513	Various types of N-glycan biosynthesis	4/972	39/8135	0.7014	0.9618	0.813	STT3B/DDOST/CHST9/MAN1C1	4
KEGG	hsa05160	Hepatitis C	17/972	157/8135	0.7054	0.9618	0.813	CHUK/PPP2CB/IRF9/CLDN17/TNF/YWHAH/E2F2/FAS/CDK6/IFNAR2/CLDN3/TNFRSF1A/SOCS3/E2F1/CLDN10/EGFR/RAF1	17
KEGG	hsa00100	Steroid biosynthesis	2/972	20/8135	0.7089	0.9618	0.813	LIPA/EBP	2
KEGG	hsa00565	Ether lipid metabolism	5/972	49/8135	0.7124	0.9618	0.813	PLD4/TMEM189/PLA2G2F/LPCAT2/GAL3ST1	5
KEGG	hsa05030	Cocaine addiction	5/972	49/8135	0.7124	0.9618	0.813	SLC18A1/CREB3L2/MAOA/JUN/CDK5R1	5
KEGG	hsa00020	Citrate cycle (TCA cycle)	3/972	30/8135	0.7129	0.9618	0.813	FH/CS/OGDHL	3
KEGG	hsa04911	Insulin secretion	9/972	86/8135	0.7141	0.9618	0.813	ADCY3/PRKCB/CREB3L2/ITPR3/CACNA1F/CAMK2G/ADCY1/PRKCA/KCNMB4	9
KEGG	hsa00920	Sulfur metabolism	1/972	10/8135	0.7201	0.9634	0.8144	SELENBP1	1
KEGG	hsa04330	Notch signaling pathway	6/972	59/8135	0.7229	0.9634	0.8144	NOTCH2/HEYL/DTX3/TLE6/DLL3/EP300	6
KEGG	hsa04024	cAMP signaling pathway	24/972	221/8135	0.724	0.9634	0.8144	GHRL/GPHA2/ADCY3/CREB3L2/PTGER2/ATP2A1/VAV3/CACNA1F/SSTR1/ACOX1/ROCK1/CALML3/JUN/SSTR2/SUCNR1/CAMK2G/EDN2/CALML5/ADCY1/EDN3/CNGB1/RAF1/EP300/SSTR5	24
KEGG	hsa00980	Metabolism of xenobiotics by cytochrome P450	8/972	78/8135	0.7295	0.965	0.8157	CYP1B1/GSTP1/EPHX1/CYP2S1/GSTT1/MGST1/ADH1A/GSTO2	8
KEGG	hsa05204	Chemical carcinogenesis - DNA adducts	7/972	69/8135	0.733	0.965	0.8157	CYP1B1/GSTP1/EPHX1/GSTT1/MGST1/AKR1C2/GSTO2	7
KEGG	hsa00052	Galactose metabolism	3/972	31/8135	0.734	0.965	0.8157	MGAM/AKR1B1/PFKM	3
KEGG	hsa05208	Chemical carcinogenesis - reactive oxygen species	24/972	223/8135	0.7402	0.9657	0.8163	AKR1A1/AKR1C3/CHUK/CYP1B1/NDUFB9/PDPK1/COX6B2/SLC26A6/EPHX1/MAP3K14/SLC25A5/ARNT/SRC/MAP3K5/HGF/NDUFA4L2/GSTT1/EPHX3/JUN/MGST1/AKR1C2/EGFR/RAF1/GSTO2	24
KEGG	hsa05168	Herpes simplex virus 1 infection	55/972	495/8135	0.7438	0.9657	0.8163	ZNF814/TLR2/C3/HLA-B/CHUK/MYD88/ZNF707/ZNF587/ZNF33B/ZNF286A/ZNF619/HLA-DPB1/ZNF543/ZNF324/ZNF205/HLA-G/IRF9/TNF/ZNF440/HLA-C/JAK2/TLR9/PILRB/ZNF589/NXF3/ZNF791/ZNF763/CCL5/FAS/IFNAR2/ZNF777/ZNF254/ZNF404/SRC/BCL2/TNFRSF1A/ZNF30/SOCS3/ZNF823/ZNF302/BCL2L1/ZNF34/ZNF550/ZNF354B/HLA-DMB/PDIA3/ZNF230/IRAK4/HLA-DMA/CD74/MAP3K7/ZNF490/ZNF19/ZNF670/ZNF548	55
KEGG	hsa00564	Glycerophospholipid metabolism	10/972	98/8135	0.749	0.9657	0.8163	DGKG/PGS1/PLD4/GPAM/PLA1A/DGKE/MBOAT2/PLA2G2F/LPCAT2/CHKA	10
KEGG	hsa01240	Biosynthesis of cofactors	16/972	153/8135	0.7529	0.9657	0.8163	AKR1A1/MAT2A/DHFR/QPRT/SHMT2/KMO/NMNAT3/ALAS2/MAT1A/MTHFD1/PDXK/GCLC/LIAS/ALPI/OXSM/CMPK2	16
KEGG	hsa04136	Autophagy - other	3/972	32/8135	0.7538	0.9657	0.8163	PPP2CB/ATG3/ATG16L1	3
KEGG	hsa00380	Tryptophan metabolism	4/972	42/8135	0.756	0.9657	0.8163	CYP1B1/ACAT2/MAOA/KMO	4
KEGG	hsa00340	Histidine metabolism	2/972	22/8135	0.7579	0.9657	0.8163	MAOA/HDC	2
KEGG	hsa04213	Longevity regulating pathway - multiple species	6/972	62/8135	0.7666	0.9657	0.8163	ADCY3/PRKAA1/IGF1/FOXO1/ADCY1/PRKAB2	6
KEGG	hsa04932	Non-alcoholic fatty liver disease	16/972	155/8135	0.7709	0.9657	0.8163	PRKAA1/ADIPOR2/NDUFB9/CDC42/COX6B2/TNF/PPARG/CEBPA/FAS/MLX/TNFRSF1A/SOCS3/MAP3K5/NDUFA4L2/JUN/PRKAB2	16
KEGG	hsa04975	Fat digestion and absorption	4/972	43/8135	0.7724	0.9657	0.8163	ACAT2/PLA2G2F/SLC27A1/APOA4	4
KEGG	hsa00982	Drug metabolism - cytochrome P450	7/972	72/8135	0.7729	0.9657	0.8163	GSTP1/MAOA/GSTT1/MGST1/ADH1A/FMO2/GSTO2	7
KEGG	hsa04910	Insulin signaling pathway	14/972	137/8135	0.7729	0.9657	0.8163	ACACB/PRKAR2A/PRKAA1/MKNK2/CRKL/PDPK1/EIF4E2/CALML3/SOCS3/PPARGC1A/FOXO1/CALML5/PRKAB2/RAF1	14
KEGG	hsa00230	Purine metabolism	13/972	128/8135	0.7744	0.9657	0.8163	PFAS/ADCY3/PPAT/IMPDH2/AMPD2/XDH/DGUOK/ENPP3/PDE6H/ENTPD4/ADCY1/ENTPD5/ENTPD2	13
KEGG	hsa04961	Endocrine and other factor-regulated calcium reabsorption	5/972	53/8135	0.7755	0.9657	0.8163	PRKCB/KL/RAB11A/PRKCA/KLK2	5
KEGG	hsa05217	Basal cell carcinoma	6/972	63/8135	0.7799	0.9676	0.8179	FZD5/FZD1/WNT5B/APC/FZD6/TCF7L1	6
KEGG	hsa00040	Pentose and glucuronate interconversions	3/972	34/8135	0.7899	0.9763	0.8252	AKR1A1/AKR1B1/KL	3
KEGG	hsa00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	2/972	24/8135	0.7996	0.981	0.8292	NDST2/EXTL1	2
KEGG	hsa04974	Protein digestion and absorption	10/972	103/8135	0.802	0.981	0.8292	COL9A2/SLC36A1/SLC1A5/SLC7A8/SLC15A1/CPA3/SLC6A19/COL20A1/SLC36A4/CELA3B	10
KEGG	hsa03022	Basal transcription factors	4/972	45/8135	0.8026	0.981	0.8292	TAF8/GTF2H3/TAF10/GTF2I	4
KEGG	hsa00500	Starch and sucrose metabolism	3/972	36/8135	0.8215	0.991	0.8377	MGAM/GYG1/ENPP3	3
KEGG	hsa00512	Mucin type O-glycan biosynthesis	3/972	36/8135	0.8215	0.991	0.8377	GALNT9/B3GNT3/GALNT6	3
KEGG	hsa04550	Signaling pathways regulating pluripotency of stem cells	14/972	143/8135	0.8237	0.991	0.8377	FZD5/ESRRB/DUSP9/FZD1/SMAD1/PCGF5/JAK2/ZFHX3/WNT5B/IGF1/APC/INHBA/FZD6/RAF1	14
KEGG	hsa00010	Glycolysis / Gluconeogenesis	6/972	67/8135	0.8276	0.991	0.8377	AKR1A1/TPI1/LDHC/PGK2/PFKM/ADH1A	6
KEGG	hsa03420	Nucleotide excision repair	4/972	47/8135	0.8294	0.991	0.8377	POLE3/RBX1/GTF2H3/POLD2	4
KEGG	hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	1/972	14/8135	0.8319	0.991	0.8377	B4GALT4	1
KEGG	hsa00563	Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	2/972	26/8135	0.8348	0.991	0.8377	PIGL/PIGB	2
KEGG	hsa04950	Maturity onset diabetes of the young	2/972	26/8135	0.8348	0.991	0.8377	PAX4/NKX6-1	2
KEGG	hsa05213	Endometrial cancer	5/972	58/8135	0.8387	0.992	0.8385	PDPK1/APC/EGFR/TCF7L1/RAF1	5
KEGG	hsa05012	Parkinson disease	27/972	266/8135	0.8454	0.9935	0.8398	PSMD14/SLC18A1/PSMB7/NDUFB9/SLC39A2/COX6B2/PSMD12/PSMA6/MAOA/RPS27A/TRAP1/SLC25A5/ITPR3/ITPR1/SLC39A5/CALML3/MAP3K5/NDUFA4L2/BCL2L1/PSMC1/UBE2J1/CAMK2G/KLC3/UBA52/PSMB6/CALML5/PSMD1	27
KEGG	hsa01040	Biosynthesis of unsaturated fatty acids	2/972	27/8135	0.8503	0.9935	0.8398	ACOX1/ACAA1	2
KEGG	hsa00604	Glycosphingolipid biosynthesis - ganglio series	1/972	15/8135	0.852	0.9935	0.8398	B3GALT4	1
KEGG	hsa00730	Thiamine metabolism	1/972	15/8135	0.852	0.9935	0.8398	ALPI	1
KEGG	hsa04917	Prolactin signaling pathway	6/972	70/8135	0.8577	0.9966	0.8424	SOCS7/JAK2/PRL/SRC/SOCS3/RAF1	6
KEGG	hsa00510	N-Glycan biosynthesis	4/972	50/8135	0.8639	1	0.8453	STT3B/DDOST/SRD5A3/MAN1C1	4
KEGG	hsa00360	Phenylalanine metabolism	1/972	16/8135	0.8697	1	0.8453	MAOA	1
KEGG	hsa04146	Peroxisome	7/972	82/8135	0.8739	1	0.8453	PEX19/PECR/MVK/XDH/ACOX1/ACSL1/ACAA1	7
KEGG	hsa04142	Lysosome	12/972	132/8135	0.8791	1	0.8453	SORT1/CTSA/CD63/CTSD/GALC/LIPA/AP3S2/CD68/SLC17A5/ENTPD4/SPAM1/HYAL4	12
KEGG	hsa03440	Homologous recombination	3/972	41/8135	0.8831	1	0.8453	RAD51/POLD2/XRCC3	3
KEGG	hsa00562	Inositol phosphate metabolism	6/972	73/8135	0.8833	1	0.8453	TPI1/MTMR4/INPP5D/PIK3C2B/MTMR7/MTMR14	6
KEGG	hsa00450	Selenocompound metabolism	1/972	17/8135	0.8853	1	0.8453	SEPHS2	1
KEGG	hsa00030	Pentose phosphate pathway	2/972	30/8135	0.889	1	0.8453	PFKM/RPIA	2
KEGG	hsa00053	Ascorbate and aldarate metabolism	2/972	30/8135	0.889	1	0.8453	AKR1A1/KL	2
KEGG	hsa05016	Huntington disease	30/972	306/8135	0.9004	1	0.8453	TFAM/PSMD14/DNAH17/PSMB7/NDUFB9/CREB3L2/SLC1A3/COX6B2/PSMD12/PSMA6/PPARG/SLC25A5/ITPR1/ACTR10/DCTN6/MAP3K5/DNAL1/NDUFA4L2/ACTR1A/PPARGC1A/GPX7/PSMC1/POLR2H/KLC3/PSMB6/DNAH10/ACTR1B/PSMD1/DNAL4/EP300	30
KEGG	hsa03460	Fanconi anemia pathway	4/972	54/8135	0.9005	1	0.8453	ATR/RAD51/FANCE/FANCF	4
KEGG	hsa01210	2-Oxocarboxylic acid metabolism	1/972	19/8135	0.9111	1	0.8453	CS	1
KEGG	hsa04723	Retrograde endocannabinoid signaling	13/972	148/8135	0.9123	1	0.8453	ADCY3/PRKCB/NDUFB9/ITPR3/CACNA1F/ITPR1/GNB2/NDUFA4L2/GNG10/DAGLB/FAAH/ADCY1/PRKCA	13
KEGG	hsa05206	MicroRNAs in cancer	30/972	310/8135	0.914	1	0.8453	NOTCH2/SPRY2/BMF/CYP1B1/DNMT3A/PRKCB/ZEB2/UBE2I/CRKL/E2F2/STMN1/CDK6/RASSF1/PIM1/BCL2/ROCK1/DNMT3B/APC/CDKN1B/EZH2/E2F1/TNR/PRKCA/PLAU/PRKCE/EGFR/THBS1/MIRLET7D/RAF1/EP300	30
KEGG	hsa05020	Prion disease	26/972	273/8135	0.9151	1	0.8453	C1QB/C1QA/C1QC/PSMD14/PSMB7/NDUFB9/CREB3L2/LAMC1/COX6B2/PSMD12/TNF/PSMA6/SLC25A5/ITPR3/CCL5/FYN/CACNA1F/ITPR1/RYR1/NDUFA4L2/NCF4/PPP3R1/PSMC1/KLC3/PSMB6/PSMD1	26
KEGG	hsa04340	Hedgehog signaling pathway	4/972	56/8135	0.9153	1	0.8453	KIF3A/BCL2/EVC2/BTRC	4
KEGG	hsa04930	Type II diabetes mellitus	3/972	46/8135	0.9251	1	0.8453	TNF/SOCS3/PRKCE	3
KEGG	hsa03020	RNA polymerase	2/972	34/8135	0.9262	1	0.8453	POLR2H/POLR1E	2
KEGG	hsa00514	Other types of O-glycan biosynthesis	3/972	47/8135	0.9316	1	0.8453	POMT2/GALNT9/GALNT6	3
KEGG	hsa04973	Carbohydrate digestion and absorption	3/972	47/8135	0.9316	1	0.8453	MGAM/PRKCB/SLC2A5	3
KEGG	hsa04622	RIG-I-like receptor signaling pathway	5/972	70/8135	0.9328	1	0.8453	CHUK/TNF/IFNW1/NFKBIB/MAP3K7	5
KEGG	hsa05230	Central carbon metabolism in cancer	5/972	70/8135	0.9328	1	0.8453	SLC1A5/LDHC/PFKM/EGFR/RAF1	5
KEGG	hsa05010	Alzheimer disease	37/972	384/8135	0.9381	1	0.8453	FZD5/PSMD14/CHUK/FZD1/PSMB7/NDUFB9/SLC39A2/ADAM10/COX6B2/PSMD12/TNF/PSMA6/ATP2A1/SLC25A5/ITPR3/FAS/CACNA1F/ITPR1/WNT5B/SLC39A5/TNFRSF1A/CALML3/MAP3K5/APC/PPID/NDUFA4L2/PPP3R1/PSMC1/KLC3/CDK5R1/FZD6/PSMB6/LPL/CALML5/LRP5/PSMD1/RAF1	37
KEGG	hsa00350	Tyrosine metabolism	2/972	36/8135	0.9401	1	0.8453	MAOA/ADH1A	2
KEGG	hsa05322	Systemic lupus erythematosus	11/972	136/8135	0.9439	1	0.8453	C1QB/C1QA/C1QC/FCGR1A/C2/C3/IL10/HLA-DPB1/TNF/HLA-DMB/HLA-DMA	11
KEGG	hsa01250	Biosynthesis of nucleotide sugars	2/972	37/8135	0.9461	1	0.8453	CMAS/NANS	2
KEGG	hsa04964	Proximal tubule bicarbonate reclamation	1/972	23/8135	0.9467	1	0.8453	CA4	1
KEGG	hsa05340	Primary immunodeficiency	2/972	38/8135	0.9515	1	0.8453	TNFRSF13C/IL2RG	2
KEGG	hsa04623	Cytosolic DNA-sensing pathway	4/972	63/8135	0.9528	1	0.8453	CHUK/CCL5/NFKBIB/POLR2H	4
KEGG	hsa04742	Taste transduction	6/972	86/8135	0.9538	1	0.8453	SCNN1B/TAS2R38/ITPR3/HTR3C/ENTPD2/P2RX2	6
KEGG	hsa03008	Ribosome biogenesis in eukaryotes	8/972	109/8135	0.9576	1	0.8453	WDR75/MDN1/NXF3/RIOK1/NAT10/FBL/SPATA5/UTP14A	8
KEGG	hsa05032	Morphine addiction	6/972	91/8135	0.9685	1	0.8453	ADCY3/PRKCB/GNB2/GNG10/ADCY1/PRKCA	6
KEGG	hsa00830	Retinol metabolism	4/972	68/8135	0.9695	1	0.8453	RDH8/CYP2S1/DHRS9/ADH1A	4
KEGG	hsa00860	Porphyrin metabolism	2/972	43/8135	0.9716	1	0.8453	FXN/ALAS2	2
KEGG	hsa00591	Linoleic acid metabolism	1/972	29/8135	0.9752	1	0.8453	PLA2G2F	1
KEGG	hsa04714	Thermogenesis	19/972	232/8135	0.9756	1	0.8453	ADCY3/PRKAA1/NDUFB9/CREB3L2/CPT1C/COX6B2/PPARG/SMARCC1/KDM1A/ACTG1/MAP3K5/NDUFA4L2/ACSL1/RPS6KA3/ARID1A/PPARGC1A/ADCY1/SMARCA2/PRKAB2	19
KEGG	hsa02010	ABC transporters	2/972	45/8135	0.9771	1	0.8453	ABCA4/ABCB6	2
KEGG	hsa04923	Regulation of lipolysis in adipocytes	2/972	56/8135	0.9932	1	0.8453	ADCY3/ADCY1	2
KEGG	hsa00190	Oxidative phosphorylation	8/972	134/8135	0.9934	1	0.8453	ATP6V1E1/PPA2/NDUFB9/COX6B2/ATP6V1C1/ATP6V1B1/ATP6V1G3/NDUFA4L2	8
KEGG	hsa05033	Nicotine addiction	1/972	40/8135	0.9939	1	0.8453	CHRNA4	1
KEGG	hsa05415	Diabetic cardiomyopathy	14/972	203/8135	0.994	1	0.8453	NOS3/PRKCB/NDUFB9/CTSD/COX6B2/ATP2A1/SLC25A5/PDK4/NDUFA4L2/NCF4/CAMK2G/PDK2/PRKCA/AGTR1	14
KEGG	hsa04978	Mineral absorption	2/972	60/8135	0.9957	1	0.8453	SLC26A6/SLC6A19	2
KEGG	hsa04976	Bile secretion	4/972	89/8135	0.9957	1	0.8453	ADCY3/AQP9/EPHX1/ADCY1	4
KEGG	hsa05034	Alcoholism	12/972	187/8135	0.9961	1	0.8453	HAT1/SLC18A1/HDAC8/CREB3L2/MAOA/CAMKK2/GNB2/CALML3/GNG10/SLC29A2/CALML5/RAF1	12
KEGG	hsa00970	Aminoacyl-tRNA biosynthesis	2/972	66/8135	0.9978	1	0.8453	SARS2/NARS2	2
KEGG	hsa04740	Olfactory transduction	11/972	440/8135	1	1	0.8453	OR10A4/ADCY3/OR2L2/OR10H3/RGS2/CALML3/OR1Q1/OR1J4/CAMK2G/CALML5/CNGB1	11