ONTOLOGY	ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	qvalue	geneID	Count
KEGG	hsa05150	Staphylococcus aureus infection	21/697	96/8135	4.723e-05	0.01549	0.01412	C1QB/C1QA/C1QC/HLA-DPB1/FPR2/FCGR2B/C3AR1/KRT27/FCGR2C/ITGAL/C3/FPR1/MASP1/CFH/HLA-DRA/C5AR1/DEFB1/HLA-DOA/ITGAM/CFD/HLA-DRB4	21
KEGG	hsa04360	Axon guidance	31/697	182/8135	0.0001505	0.02469	0.0225	NRP1/SEMA4G/NEO1/SEMA3B/ROBO3/PARD3/NTN3/PLXNB2/RAC3/SRGAP1/NTNG2/ROCK1/MYL9/SEMA3C/SEMA6A/PIK3R1/PARD6B/ABLIM2/CXCL12/PLXNA3/PPP3R1/SEMA5B/PARD6G/NTNG1/PLXNA1/WNT4/RAF1/SEMA4D/PLXNB1/CDC42/SMO	31
KEGG	hsa00520	Amino sugar and nucleotide sugar metabolism	12/697	49/8135	0.0006772	0.07405	0.06749	CHIT1/PMM2/HK2/RENBP/CYB5R2/NPL/GMPPB/CMAS/HK1/HEXA/CYB5RL/PGM3	12
KEGG	hsa04933	AGE-RAGE signaling pathway in diabetic complications	18/697	100/8135	0.001877	0.154	0.1403	PRKCE/NOS3/TGFB1/PIM1/COL4A5/COL4A6/PIK3R1/PRKCD/COL1A2/AGTR1/TGFBR2/FN1/COL4A1/CDC42/AKT2/VCAM1/PLCB1/FOXO1	18
KEGG	hsa04926	Relaxin signaling pathway	21/697	129/8135	0.002991	0.1962	0.1788	NOS3/ADCY3/EDNRB/EGFR/ADCY1/TGFB1/COL4A5/GNG8/SHC3/COL4A6/GNG3/RLN1/PIK3R1/GNG12/GNG4/COL1A2/TGFBR2/RAF1/COL4A1/AKT2/PLCB1	21
KEGG	hsa04514	Cell adhesion molecules	23/697	149/8135	0.003892	0.1981	0.1806	HLA-DPB1/NEO1/ITGA4/CDH15/NTNG2/CDH4/NLGN2/SDC1/HLA-G/PDCD1LG2/ITGAL/NLGN1/OCLN/CD2/NTNG1/NLGN4X/HLA-DRA/CLDN4/HLA-DOA/ITGAM/VCAM1/NRCAM/HLA-DRB4	23
KEGG	hsa04930	Type II diabetes mellitus	10/697	46/8135	0.004769	0.1981	0.1806	PRKCE/HK2/SOCS3/IRS1/PIK3R1/ABCC8/PKLR/HK1/PRKCD/CACNA1G	10
KEGG	hsa04610	Complement and coagulation cascades	15/697	85/8135	0.005274	0.1981	0.1806	C1QB/VSIG4/C1QA/C1QC/SERPINA1/C3AR1/C3/CLU/MASP1/CFH/PROS1/C5AR1/CR1/ITGAM/CFD	15
KEGG	hsa04380	Osteoclast differentiation	20/697	128/8135	0.005966	0.1981	0.1806	FCGR2B/SOCS3/LILRA1/TGFB1/IFNGR1/TNFRSF11A/FCGR2C/BTK/LILRB2/PIK3R1/TYK2/PPP3R1/LILRA3/JUND/LILRA5/TGFBR2/MITF/SQSTM1/AKT2/CHUK	20
KEGG	hsa05165	Human papillomavirus infection	42/697	331/8135	0.00604	0.1981	0.1806	PARD3/ITGA4/ITGB4/EGFR/TCIRG1/ATR/PPP2CB/TNN/COL4A5/TCF7L1/COL4A6/LLGL1/ATP6V1E1/HLA-G/CDK6/PIK3R1/PARD6B/TYK2/PARD6G/HES2/SLC9A3R1/PPP2R2D/DVL1/COL1A2/WNT4/RAF1/PPP2R3B/SCRIB/FN1/COL4A1/FZD5/TRAF3/CDC42/AXIN1/ITGA5/AKT2/CHUK/FZD10/LAMB2/TNR/COL6A1/FOXO1	42
KEGG	hsa04151	PI3K-Akt signaling pathway	44/697	354/8135	0.007262	0.2002	0.1825	TCL1B/FGF5/NTRK1/ITGA4/NOS3/ITGB4/FGF6/EGFR/AREG/PPP2CB/TNN/COL4A5/GNG8/COL4A6/BCL2L1/OSMR/IRS1/GNG3/FGF17/CDK6/PIK3R1/NGFR/GNG12/TLR4/GNG4/MYB/PPP2R2D/COL1A2/RXRA/PRLR/IL2RG/CSH1/RAF1/PPP2R3B/FN1/COL4A1/ITGA5/AKT2/CHUK/LAMB2/TNR/PRKAA1/PGF/COL6A1	44
KEGG	hsa04512	ECM-receptor interaction	15/697	88/8135	0.007324	0.2002	0.1825	ITGA4/ITGB4/TNN/COL4A5/CD47/COL4A6/SDC1/COL1A2/FN1/COL4A1/ITGA5/GP9/LAMB2/TNR/COL6A1	15
KEGG	hsa04659	Th17 cell differentiation	17/697	108/8135	0.01	0.2254	0.2055	HLA-DPB1/TGFB1/IFNGR1/IL17A/EBI3/TYK2/PPP3R1/RXRG/RXRA/TGFBR2/IL2RG/HLA-DRA/IL21R/HLA-DOA/CHUK/IL27/HLA-DRB4	17
KEGG	hsa01230	Biosynthesis of amino acids	13/697	75/8135	0.01053	0.2254	0.2055	ASNS/GLUL/ALDOB/TKT/PKLR/RPIA/CBS/MAT2A/ALDH18A1/ASS1/MAT1A/PAH/PC	13
KEGG	hsa04510	Focal adhesion	27/697	201/8135	0.01241	0.2254	0.2055	PIP5K1A/ITGA4/ITGB4/RAC3/EGFR/ROCK1/ACTG1/MYL9/TNN/COL4A5/SHC3/COL4A6/CRKL/PIK3R1/PPP1R12B/COL1A2/RAF1/FN1/COL4A1/PRKCG/CDC42/ITGA5/AKT2/LAMB2/TNR/PGF/COL6A1	27
KEGG	hsa05142	Chagas disease	16/697	102/8135	0.01264	0.2254	0.2055	C1QB/C1QA/C1QC/ADCY1/TGFB1/PPP2CB/IFNGR1/PIK3R1/TLR4/C3/IRAK4/PPP2R2D/TGFBR2/AKT2/CHUK/PLCB1	16
KEGG	hsa05146	Amoebiasis	16/697	102/8135	0.01264	0.2254	0.2055	ADCY1/TGFB1/COL4A5/COL4A6/PIK3R1/TLR4/HSPB1/MUC2/COL1A2/FN1/COL4A1/PRKCG/ITGAM/LAMB2/RAB5C/PLCB1	16
KEGG	hsa04062	Chemokine signaling pathway	26/697	192/8135	0.01267	0.2254	0.2055	PARD3/ADCY3/CCL17/RAC3/ADCY1/ROCK1/GNG8/CCR8/SHC3/CRKL/GNG3/PIK3R1/GNG12/CXCL12/CCL21/GNG4/PRKCD/CCL16/RAF1/CDC42/AKT2/CHUK/DOCK2/CXCL14/GRK6/PLCB1	26
KEGG	hsa05140	Leishmaniasis	13/697	77/8135	0.01306	0.2254	0.2055	HLA-DPB1/ITGA4/TGFB1/IFNGR1/FCGR2C/TLR4/C3/IRAK4/HLA-DRA/CR1/HLA-DOA/ITGAM/HLA-DRB4	13
KEGG	hsa04936	Alcoholic liver disease	20/697	142/8135	0.01807	0.2657	0.2422	C1QB/C1QA/C1QC/C3AR1/IL17RC/ACACA/TCF7L1/IL17A/TLR4/C3/IRAK4/LPIN2/CPT1C/CAMKK2/C5AR1/TRAF3/AKT2/CHUK/PRKAA1/FOXO1	20
KEGG	hsa04929	GnRH secretion	11/697	64/8135	0.01895	0.2657	0.2422	KCNN1/CACNA1I/PIK3R1/GABBR2/HCN2/RAF1/CACNA1G/PRKCG/AKT2/GNRH2/PLCB1	11
KEGG	hsa04810	Regulation of actin cytoskeleton	28/697	218/8135	0.01933	0.2657	0.2422	PIP5K1A/FGF5/ITGA4/BAIAP2/ITGB4/FGF6/RAC3/EGFR/ROCK1/ACTG1/MYL9/CRKL/FGF17/PIK3R1/GNG12/ITGAL/CXCL12/ACTR3B/SLC9A1/CYFIP2/MYH14/PPP1R12B/ARPC5/RAF1/FN1/CDC42/ITGA5/ITGAM	28
KEGG	hsa04270	Vascular smooth muscle contraction	19/697	134/8135	0.01955	0.2657	0.2422	PRKCE/ADCY3/ADCY1/ROCK1/NPPB/MYL9/RAMP1/MYH14/PPP1R12B/PRKCD/NPPC/AGTR1/NPR1/RAF1/ACTG2/PRKCG/CALML4/NPPA/PLCB1	19
KEGG	hsa04015	Rap1 signaling pathway	27/697	210/8135	0.0211	0.2657	0.2422	FGF5/PARD3/ARAP3/ADCY3/FGF6/RAC3/EGFR/ADCY1/ACTG1/CRKL/FGF17/PIK3R1/PARD6B/NGFR/ITGAL/CTNND1/SIPA1L1/PARD6G/FPR1/RAF1/PRKCG/CDC42/ITGAM/AKT2/CALML4/PGF/PLCB1	27
KEGG	hsa05321	Inflammatory bowel disease	11/697	65/8135	0.02111	0.2657	0.2422	HLA-DPB1/MAF/TGFB1/IFNGR1/IL17A/TLR4/IL2RG/HLA-DRA/IL21R/HLA-DOA/HLA-DRB4	11
KEGG	hsa04662	B cell receptor signaling pathway	13/697	82/8135	0.02141	0.2657	0.2422	FCGR2B/RAC3/LILRA1/BTK/LILRB2/PIK3R1/PPP3R1/LILRA3/LILRA5/RAF1/AKT2/CHUK/MALT1	13
KEGG	hsa04921	Oxytocin signaling pathway	21/697	154/8135	0.02187	0.2657	0.2422	NOS3/ADCY3/EGFR/ADCY1/ROCK1/ACTG1/MYL9/RYR1/PPP3R1/MAP2K5/PPP1R12B/CAMKK2/NPR1/RAF1/CACNG1/PRKCG/CALML4/PRKAA1/KCNJ4/NPPA/PLCB1	21
KEGG	hsa04390	Hippo signaling pathway	21/697	157/8135	0.02651	0.3022	0.2754	PARD3/AREG/ACTG1/TGFB1/PPP2CB/TCF7L1/LLGL1/PARD6B/PARD6G/PPP2R2D/DVL1/WNT4/NKD1/TGFBR2/SCRIB/FZD5/AXIN1/NKD2/FZD10/WWTR1/SMAD1	21
KEGG	hsa04022	cGMP-PKG signaling pathway	22/697	167/8135	0.02748	0.3022	0.2754	PRKCE/NOS3/ADCY3/EDNRB/ADCY1/ROCK1/NPPB/MYL9/IRS1/ATP1A4/PPP3R1/ADORA3/MYH6/NPPC/AGTR1/NPR1/RAF1/AKT2/CALML4/MEF2A/NPPA/PLCB1	22
KEGG	hsa05418	Fluid shear stress and atherosclerosis	19/697	139/8135	0.02764	0.3022	0.2754	GPC1/NOS3/RAC3/ACTG1/SDC1/PIK3R1/GSTT1/TRPV4/MAP2K5/NPPC/ASS1/SQSTM1/NQO1/AKT2/CHUK/VCAM1/CALML4/PRKAA1/MEF2A	19
KEGG	hsa05226	Gastric cancer	20/697	149/8135	0.0289	0.3058	0.2787	FGF5/FGF6/EGFR/TGFB1/TCF7L1/SHC3/FGF17/PIK3R1/LRP5/MUC2/DVL1/RXRG/RXRA/WNT4/TGFBR2/RAF1/FZD5/AXIN1/AKT2/FZD10	20
KEGG	hsa04145	Phagosome	20/697	152/8135	0.0348	0.3486	0.3177	HLA-DPB1/TAP2/FCGR2B/TCIRG1/ACTG1/FCGR2C/SCARB1/COLEC12/ATP6V1E1/HLA-G/TLR4/C3/STX12/MRC2/HLA-DRA/HLA-DOA/ITGA5/ITGAM/RAB5C/HLA-DRB4	20
KEGG	hsa02010	ABC transporters	8/697	45/8135	0.03525	0.3486	0.3177	ABCB6/TAP2/ABCB8/ABCC8/ABCA4/ABCC5/DEFB1/ABCD2	8
KEGG	hsa04666	Fc gamma R-mediated phagocytosis	14/697	97/8135	0.03614	0.3486	0.3177	PRKCE/PIP5K1A/FCGR2B/DNM2/CRKL/PIK3R1/ACTR3B/AMPH/ARPC5/PRKCD/RAF1/PRKCG/CDC42/AKT2	14
KEGG	hsa04925	Aldosterone synthesis and secretion	14/697	98/8135	0.03898	0.3649	0.3326	PRKCE/ADCY3/ADCY1/SCARB1/CACNA1I/ATP1A4/LDLR/AGTR1/NPR1/CACNA1G/PRKCG/CALML4/NPPA/PLCB1	14
KEGG	hsa00515	Mannose type O-glycan biosynthesis	5/697	23/8135	0.04188	0.3649	0.3326	FKRP/ST3GAL3/FUT9/FKTN/POMT2	5
KEGG	hsa03430	Mismatch repair	5/697	23/8135	0.04188	0.3649	0.3326	MSH6/RFC5/MSH2/POLD2/RPA2	5
KEGG	hsa04010	MAPK signaling pathway	34/697	294/8135	0.04317	0.3649	0.3326	FGF5/NTRK1/TAOK3/FGF6/RAC3/EGFR/AREG/TGFB1/MAP4K4/CACNA1I/CRKL/FGF17/NGFR/GNG12/PPP5C/MAPK8IP3/PPP3R1/IRAK4/MAP2K5/MAP3K4/PTPRR/HSPB1/JUND/TGFBR2/RAF1/CACNA1G/CACNG1/MAP4K2/PRKCG/CDC42/AKT2/CHUK/PGF/MAP4K1	34
KEGG	hsa05205	Proteoglycans in cancer	25/697	205/8135	0.04491	0.3649	0.3326	TWIST2/GPC1/EGFR/ANK2/ROCK1/ANK1/ACTG1/TGFB1/SDC1/PIK3R1/SLC9A1/TLR4/PPP1R12B/COL1A2/WNT4/RAF1/FN1/FZD5/PRKCG/CDC42/SMO/ITGA5/AKT2/FZD10/TWIST1	25
KEGG	hsa00513	Various types of N-glycan biosynthesis	7/697	39/8135	0.04529	0.3649	0.3326	STT3B/B4GALNT4/MAN1C1/ST3GAL3/B4GALNT3/MGAT4C/HEXA	7
KEGG	hsa04916	Melanogenesis	14/697	101/8135	0.04848	0.3649	0.3326	ADCY3/EDNRB/ADCY1/TCF7L1/TYR/DVL1/WNT4/MITF/RAF1/FZD5/PRKCG/FZD10/CALML4/PLCB1	14
KEGG	hsa04927	Cortisol synthesis and secretion	10/697	65/8135	0.04855	0.3649	0.3326	ADCY3/ADCY1/SCARB1/CACNA1I/LDLR/AGTR1/NCEH1/CACNA1G/PDE8B/PLCB1	10
KEGG	hsa05222	Small cell lung cancer	13/697	92/8135	0.04911	0.3649	0.3326	COL4A5/COL4A6/BCL2L1/CDK6/PIK3R1/RXRG/RXRA/FN1/COL4A1/TRAF3/AKT2/CHUK/LAMB2	13
KEGG	hsa04371	Apelin signaling pathway	18/697	139/8135	0.04981	0.3649	0.3326	PRKCE/NOS3/TFAM/ADCY3/ADCY1/GNG8/GNG3/GNG12/RYR1/SLC9A1/GNG4/AGTR1/RAF1/AKT2/CALML4/PRKAA1/MEF2A/PLCB1	18
KEGG	hsa05225	Hepatocellular carcinoma	21/697	168/8135	0.05006	0.3649	0.3326	EGFR/ACTG1/TGFB1/TCF7L1/SHC3/BCL2L1/CDK6/PIK3R1/LRP5/GSTT1/DVL1/WNT4/TGFBR2/RAF1/FZD5/PRKCG/NQO1/AXIN1/AKT2/FZD10/SMARCA4	21
KEGG	hsa04530	Tight junction	21/697	169/8135	0.05278	0.3682	0.3356	PRKCE/PARD3/ROCK1/ACTG1/PPP2CB/MYL9/LLGL1/PARD6B/ACTR3B/OCLN/TJP3/PARD6G/MYH14/ARPC5/SLC9A3R1/PPP2R2D/SCRIB/CLDN4/ARHGEF18/CDC42/PRKAA1	21
KEGG	hsa05323	Rheumatoid arthritis	13/697	93/8135	0.05282	0.3682	0.3356	HLA-DPB1/TCIRG1/TGFB1/TNFRSF11A/ATP6V1E1/LTB/IL17A/ITGAL/CXCL12/TLR4/HLA-DRA/HLA-DOA/HLA-DRB4	13
KEGG	hsa05152	Tuberculosis	22/697	180/8135	0.05614	0.3682	0.3356	HLA-DPB1/FCGR2B/TCIRG1/TGFB1/IFNGR1/FCGR2C/TLR4/C3/PPP3R1/IRAK4/MRC2/HLA-DRA/RAF1/CR1/HLA-DOA/ITGAM/AKT2/CALML4/RAB5C/MALT1/CLEC4E/HLA-DRB4	22
KEGG	hsa05212	Pancreatic cancer	11/697	76/8135	0.05794	0.3682	0.3356	RAC3/EGFR/TGFB1/BCL2L1/CDK6/PIK3R1/TGFBR2/RAF1/CDC42/AKT2/CHUK	11
KEGG	hsa00051	Fructose and mannose metabolism	6/697	33/8135	0.05847	0.3682	0.3356	ENOSF1/PMM2/HK2/GMPPB/ALDOB/HK1	6
KEGG	hsa05210	Colorectal cancer	12/697	86/8135	0.06191	0.3682	0.3356	MSH6/MSH2/RAC3/EGFR/AREG/TGFB1/TCF7L1/PIK3R1/TGFBR2/RAF1/AXIN1/AKT2	12
KEGG	hsa00511	Other glycan degradation	4/697	18/8135	0.06216	0.3682	0.3356	AGA/NEU3/HEXA/ENGASE	4
KEGG	hsa04370	VEGF signaling pathway	9/697	59/8135	0.0622	0.3682	0.3356	NOS3/RAC3/PIK3R1/PPP3R1/HSPB1/RAF1/PRKCG/CDC42/AKT2	9
KEGG	hsa05100	Bacterial invasion of epithelial cells	11/697	77/8135	0.06262	0.3682	0.3356	ACTG1/DNM2/SHC3/CRKL/PIK3R1/ACTR3B/ARPC5/FN1/CDC42/ITGA5/CD2AP	11
KEGG	hsa00563	Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	5/697	26/8135	0.06634	0.3682	0.3356	PIGF/PIGG/PIGL/PIGK/PIGX	5
KEGG	hsa00790	Folate biosynthesis	5/697	26/8135	0.06634	0.3682	0.3356	AKR1C3/PCBD2/TH/PAH/QDPR	5
KEGG	hsa04060	Cytokine-cytokine receptor interaction	33/697	295/8135	0.06683	0.3682	0.3356	TNFRSF14/IL17B/CCL17/TNFRSF8/TGFB1/IFNGR1/IL16/IL17RC/TNFRSF11A/CCR8/OSMR/CNTFR/LTB/IL17A/BMP10/NGFR/EBI3/THPO/CXCL12/CCL21/TNFRSF1B/PRLR/CCL16/TGFBR2/IL2RG/CSH1/IL21R/MSTN/IL33/IL20RA/TNFRSF10B/CXCL14/IL27	33
KEGG	hsa04928	Parathyroid hormone synthesis, secretion and action	14/697	106/8135	0.06768	0.3682	0.3356	ADCY3/EGFR/ADCY1/LRP5/JUND/SLC9A3R1/RXRG/RXRA/PDE4C/RAF1/PRKCG/PTH1R/MEF2A/PLCB1	14
KEGG	hsa05416	Viral myocarditis	9/697	60/8135	0.0679	0.3682	0.3356	HLA-DPB1/RAC3/ACTG1/HLA-G/ITGAL/MYH6/HLA-DRA/HLA-DOA/HLA-DRB4	9
KEGG	hsa04920	Adipocytokine signaling pathway	10/697	69/8135	0.06809	0.3682	0.3356	SOCS3/IRS1/CPT1C/TNFRSF1B/CAMKK2/RXRG/RXRA/AKT2/CHUK/PRKAA1	10
KEGG	hsa05168	Herpes simplex virus 1 infection	52/697	495/8135	0.06896	0.3682	0.3356	ZNF589/ZNF354B/HLA-DPB1/ZNF91/ZNF560/PILRB/TAP2/ZFP90/TNFRSF14/ZFP57/ZNF205/ZNF675/SOCS3/ZNF33B/IFNGR1/ZNF514/ZNF479/ZNF808/ZNF517/HCFC1/BCL2L1/HLA-G/ZNF337/ZNF324/PIK3R1/ZNF316/TYK2/C3/ZNF763/IRAK4/ZNF417/ZNF670/CFP/ZNF573/ZNF286A/ZNF439/ZNF212/ZNF169/HLA-DRA/ZNF33A/ZNF404/ZNF93/ZNF780B/TRAF3/HLA-DOA/ITGA5/AKT2/CHUK/ZNF175/ZNF528/ZNF253/HLA-DRB4	52
KEGG	hsa04713	Circadian entrainment	13/697	97/8135	0.06959	0.3682	0.3356	ADCY3/ADCY1/GNG8/CACNA1I/GNG3/GNG12/RYR1/GNG4/CACNA1G/PRKCG/CALML4/PLCB1/NOS1AP	13
KEGG	hsa04975	Fat digestion and absorption	7/697	43/8135	0.07082	0.3687	0.336	ACAT2/SCARB1/AGPAT1/PNLIPRP2/DGAT1/APOA4/APOA1	7
KEGG	hsa04218	Cellular senescence	19/697	156/8135	0.07408	0.3797	0.346	ATR/TGFB1/CCNB1/HLA-G/CDK6/HIPK1/PIK3R1/RAD50/PPP3R1/TRPV4/CAPN1/TGFBR2/RAF1/IGFBP3/CHEK2/SQSTM1/AKT2/CALML4/FOXO1	19
KEGG	hsa05135	Yersinia infection	17/697	137/8135	0.07654	0.3862	0.352	PIP5K1A/ITGA4/BAIAP2/RAC3/ROCK1/ACTG1/CRKL/PIK3R1/ACTR3B/TLR4/IRAK4/ARPC5/FN1/CDC42/ITGA5/AKT2/CHUK	17
KEGG	hsa04520	Adherens junction	10/697	71/8135	0.07949	0.3928	0.358	PARD3/BAIAP2/RAC3/EGFR/ACTG1/TCF7L1/SSX2IP/CTNND1/TGFBR2/CDC42	10
KEGG	hsa04213	Longevity regulating pathway - multiple species	9/697	62/8135	0.08023	0.3928	0.358	ADCY3/ADCY1/IRS1/PIK3R1/EIF4EBP2/AKT2/SOD1/PRKAA1/FOXO1	9
KEGG	hsa04071	Sphingolipid signaling pathway	15/697	119/8135	0.08297	0.3944	0.3595	PRKCE/NOS3/RAC3/ROCK1/PPP2CB/ACER1/PIK3R1/SGPP2/ADORA3/PPP2R2D/RAF1/PPP2R3B/PRKCG/AKT2/PLCB1	15
KEGG	hsa04722	Neurotrophin signaling pathway	15/697	119/8135	0.08297	0.3944	0.3595	NTRK1/SHC3/CRKL/IRS1/PIK3R1/NGFR/IRAK4/MAP2K5/ARHGDIG/PRKCD/SH2B2/RAF1/CDC42/AKT2/CALML4	15
KEGG	hsa05032	Morphine addiction	12/697	91/8135	0.08705	0.4079	0.3718	ADCY3/ADCY1/GNG8/GNG3/PDE7B/GNG12/GNG4/GABBR2/PDE4C/PRKCG/PDE8B/GRK6	12
KEGG	hsa01250	Biosynthesis of nucleotide sugars	6/697	37/8135	0.09224	0.4115	0.3751	PMM2/HK2/GMPPB/CMAS/HK1/PGM3	6
KEGG	hsa05143	African trypanosomiasis	6/697	37/8135	0.09224	0.4115	0.3751	PRKCG/HPR/VCAM1/NPPA/APOA1/PLCB1	6
KEGG	hsa04658	Th1 and Th2 cell differentiation	12/697	92/8135	0.09275	0.4115	0.3751	HLA-DPB1/MAF/IFNGR1/RUNX3/TYK2/PPP3R1/DLL3/IL2RG/HLA-DRA/HLA-DOA/CHUK/HLA-DRB4	12
KEGG	hsa03450	Non-homologous end-joining	3/697	13/8135	0.0938	0.4115	0.3751	RAD50/NHEJ1/DNTT	3
KEGG	hsa05164	Influenza A	20/697	171/8135	0.0941	0.4115	0.3751	HLA-DPB1/SOCS3/PRSS2/ACTG1/IFNGR1/CDK6/PIK3R1/TYK2/TLR4/IRAK4/HLA-DRA/RAF1/IL33/TRAF3/HLA-DOA/AKT2/CHUK/TMPRSS4/TNFRSF10B/HLA-DRB4	20
KEGG	hsa05145	Toxoplasmosis	14/697	112/8135	0.09663	0.417	0.3801	HLA-DPB1/TGFB1/IFNGR1/BCL2L1/TYK2/TLR4/IRAK4/LDLR/HLA-DRA/HLA-DOA/AKT2/CHUK/LAMB2/HLA-DRB4	14
KEGG	hsa04970	Salivary secretion	12/697	93/8135	0.09866	0.4203	0.383	PRB1/ADCY3/ADCY1/BST1/ATP1A4/SLC9A1/CST4/LPO/CST2/PRKCG/CALML4/PLCB1	12
KEGG	hsa04973	Carbohydrate digestion and absorption	7/697	47/8135	0.1034	0.4349	0.3963	SLC2A5/HK2/PIK3R1/ATP1A4/HK1/AKT2/PLCB1	7
KEGG	hsa04670	Leukocyte transendothelial migration	14/697	114/8135	0.1078	0.4474	0.4078	ITGA4/ROCK1/ACTG1/MYL9/PIK3R1/ITGAL/CTNND1/CXCL12/OCLN/PRKCG/CLDN4/CDC42/ITGAM/VCAM1	14
KEGG	hsa05133	Pertussis	10/697	76/8135	0.1129	0.4538	0.4136	C1QB/C1QA/C1QC/TLR4/C3/IRAK4/CASP7/ITGA5/ITGAM/CALML4	10
KEGG	hsa05220	Chronic myeloid leukemia	10/697	76/8135	0.1129	0.4538	0.4136	TGFB1/SHC3/BCL2L1/CRKL/CDK6/PIK3R1/TGFBR2/RAF1/AKT2/CHUK	10
KEGG	hsa04934	Cushing syndrome	18/697	155/8135	0.1135	0.4538	0.4136	ADCY3/EGFR/ADCY1/TCF7L1/SCARB1/CACNA1I/CDK6/LDLR/DVL1/AGTR1/WNT4/NCEH1/CACNA1G/FZD5/PDE8B/AXIN1/FZD10/PLCB1	18
KEGG	hsa05310	Asthma	5/697	31/8135	0.1212	0.4775	0.4352	HLA-DPB1/HLA-DRA/HLA-DOA/EPX/HLA-DRB4	5
KEGG	hsa04672	Intestinal immune network for IgA production	7/697	49/8135	0.1223	0.4775	0.4352	HLA-DPB1/ITGA4/TGFB1/CXCL12/HLA-DRA/HLA-DOA/HLA-DRB4	7
KEGG	hsa05224	Breast cancer	17/697	147/8135	0.1247	0.4782	0.4359	FGF5/FGF6/EGFR/TCF7L1/SHC3/FGF17/CDK6/PIK3R1/LRP5/DLL3/DVL1/WNT4/RAF1/FZD5/AXIN1/AKT2/FZD10	17
KEGG	hsa04910	Insulin signaling pathway	16/697	137/8135	0.1254	0.4782	0.4359	HK2/SOCS3/ACACA/SHC3/CRKL/IRS1/PPP1R3E/PIK3R1/PKLR/HK1/SH2B2/RAF1/AKT2/CALML4/PRKAA1/FOXO1	16
KEGG	hsa04750	Inflammatory mediator regulation of TRP channels	12/697	98/8135	0.1315	0.4861	0.443	PRKCE/NTRK1/ADCY3/ADCY1/TRPV1/PIK3R1/TRPV2/TRPV4/PRKCD/PRKCG/CALML4/PLCB1	12
KEGG	hsa00603	Glycosphingolipid biosynthesis - globo and isoglobo series	3/697	15/8135	0.1316	0.4861	0.443	GLA/FUT9/HEXA	3
KEGG	hsa00230	Purine metabolism	15/697	128/8135	0.1319	0.4861	0.443	AMPD2/ADA/ADCY3/HDDC2/ADCY1/XDH/PFAS/NME3/PDE7B/ENPP4/PPAT/PDE4C/RRM1/NPR1/PDE8B	15
KEGG	hsa04136	Autophagy - other	5/697	32/8135	0.1342	0.4889	0.4456	ATG4B/PPP2CB/ULK2/ATG7/ATG2A	5
KEGG	hsa04014	Ras signaling pathway	25/697	232/8135	0.1366	0.4899	0.4465	FGF5/NTRK1/FGF6/RAC3/EGFR/RASAL3/GNG8/SHC3/BCL2L1/GNG3/FGF17/PIK3R1/NGFR/GNG12/SYNGAP1/GNG4/RGL1/RAF1/PRKCG/CDC42/AKT2/CHUK/CALML4/PGF/RAB5C	25
KEGG	hsa04640	Hematopoietic cell lineage	12/697	99/8135	0.1388	0.4899	0.4465	HLA-DPB1/ITGA4/THPO/CD2/HLA-DRA/CR1/HLA-DOA/ITGA5/ITGAM/GP9/DNTT/HLA-DRB4	12
KEGG	hsa05166	Human T-cell leukemia virus 1 infection	24/697	222/8135	0.1389	0.4899	0.4465	NRP1/HLA-DPB1/ADCY3/ANAPC1/ADCY1/ATR/TGFB1/BCL2L1/HLA-G/ANAPC13/PIK3R1/ITGAL/PPP3R1/TRRAP/POLB/TCF3/TGFBR2/IL2RG/HLA-DRA/CHEK2/HLA-DOA/AKT2/CHUK/HLA-DRB4	24
KEGG	hsa05170	Human immunodeficiency virus 1 infection	23/697	212/8135	0.1412	0.4908	0.4473	TAP2/RAC3/ATR/GNG8/CCNB1/BCL2L1/CRKL/HLA-G/GNG3/PIK3R1/GNG12/TLR4/PPP3R1/IRAK4/GNG4/TNFRSF1B/RAF1/PRKCG/DDB1/APOBEC3F/AKT2/CHUK/CALML4	23
KEGG	hsa04917	Prolactin signaling pathway	9/697	70/8135	0.1421	0.4908	0.4473	SOCS3/TNFRSF11A/SHC3/PIK3R1/SOCS7/PRLR/RAF1/TH/AKT2	9
KEGG	hsa04977	Vitamin digestion and absorption	4/697	24/8135	0.1448	0.4946	0.4508	SLC5A6/SCARB1/APOA4/APOA1	4
KEGG	hsa03410	Base excision repair	5/697	33/8135	0.1477	0.4955	0.4516	NEIL2/MUTYH/POLB/POLD2/NEIL3	5
KEGG	hsa00561	Glycerolipid metabolism	8/697	61/8135	0.148	0.4955	0.4516	GPAM/GLA/AGPAT3/LPIN2/AGPAT1/PNLIPRP2/DGAT1/DGKZ	8
KEGG	hsa04140	Autophagy - animal	16/697	141/8135	0.1498	0.4962	0.4522	ATG4B/PPP2CB/BCL2L1/IRS1/PIK3R1/ULK2/BNIP3/WDR41/PRKCD/CAMKK2/ATG7/RAF1/ATG2A/SQSTM1/AKT2/PRKAA1	16
KEGG	hsa04630	JAK-STAT signaling pathway	18/697	162/8135	0.1523	0.4995	0.4552	SOCS3/EGFR/IFNGR1/PIM1/BCL2L1/OSMR/CNTFR/PIK3R1/SOCS7/THPO/TYK2/PRLR/IL2RG/CSH1/RAF1/IL21R/IL20RA/AKT2	18
KEGG	hsa04728	Dopaminergic synapse	15/697	132/8135	0.158	0.5066	0.4617	SLC18A1/PPP2CB/GNG8/GNG3/CLOCK/GNG12/KIF5C/GNG4/PPP2R2D/PPP2R3B/TH/PRKCG/AKT2/CALML4/PLCB1	15
KEGG	hsa05131	Shigellosis	26/697	247/8135	0.158	0.5066	0.4617	PRKCE/HK2/EGFR/ROCK1/TECPR1/ACTG1/MYL9/BCL2L1/CRKL/PIK3R1/ACTR3B/TLR4/C3/BNIP3/HK1/ARPC5/CAPN1/PRKCD/SQSTM1/CDC42/ITGA5/AKT2/CHUK/MALT1/PLCB1/FOXO1	26
KEGG	hsa05218	Melanoma	9/697	72/8135	0.1606	0.5066	0.4617	FGF5/FGF6/EGFR/FGF17/CDK6/PIK3R1/MITF/RAF1/AKT2	9
KEGG	hsa05223	Non-small cell lung cancer	9/697	72/8135	0.1606	0.5066	0.4617	EGFR/CDK6/PIK3R1/KIF5C/RXRG/RXRA/RAF1/PRKCG/AKT2	9
KEGG	hsa04974	Protein digestion and absorption	12/697	103/8135	0.1697	0.5297	0.4827	COL17A1/CELA3B/PRSS2/COL4A5/COL4A6/ATP1A4/COL20A1/SLC7A7/COL1A2/COL4A1/COL16A1/COL6A1	12
KEGG	hsa04962	Vasopressin-regulated water reabsorption	6/697	44/8135	0.1712	0.5297	0.4827	ADCY3/ARHGDIG/DYNC2LI1/DYNLL2/AQP2/RAB5C	6
KEGG	hsa04724	Glutamatergic synapse	13/697	114/8135	0.1762	0.5374	0.4898	ADCY3/ADCY1/SLC17A8/SHANK1/GNG8/GNG3/GLUL/GNG12/SLC1A7/PPP3R1/GNG4/PRKCG/PLCB1	13
KEGG	hsa04064	NF-kappa B signaling pathway	12/697	104/8135	0.178	0.5374	0.4898	TNFRSF11A/BCL2L1/BTK/LTB/CXCL12/CCL21/TLR4/IRAK4/TRAF3/CHUK/VCAM1/MALT1	12
KEGG	hsa04144	Endocytosis	26/697	251/8135	0.1786	0.5374	0.4898	PIP5K1A/DAB2/PARD3/ARAP3/EGFR/DNM2/ARAP1/EHD2/HLA-G/GBF1/PARD6B/AGAP3/ACTR3B/KIF5C/AMPH/SNF8/LDLR/PARD6G/ARPC5/TGFBR2/ZFYVE9/IL2RG/CDC42/RAB5C/GRK6/FOLR1	26
KEGG	hsa03030	DNA replication	5/697	36/8135	0.1914	0.5706	0.5201	RFC5/PRIM1/MCM5/POLD2/RPA2	5
KEGG	hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	4/697	27/8135	0.1965	0.5807	0.5293	FUT5/ST3GAL3/FUT9/FUT7	4
KEGG	hsa04923	Regulation of lipolysis in adipocytes	7/697	56/8135	0.2005	0.5872	0.5352	ADCY3/ADCY1/IRS1/PIK3R1/NPR1/AKT2/NPPA	7
KEGG	hsa04070	Phosphatidylinositol signaling system	11/697	97/8135	0.2067	0.5939	0.5413	PIP5K1A/PPIP5K1/OCRL/PIK3R1/INPP5F/DGKZ/INPP5E/PRKCG/CALML4/PLCB1/IPPK	11
KEGG	hsa04960	Aldosterone-regulated sodium reabsorption	5/697	37/8135	0.2069	0.5939	0.5413	NR3C2/IRS1/PIK3R1/ATP1A4/PRKCG	5
KEGG	hsa00620	Pyruvate metabolism	6/697	47/8135	0.2115	0.5939	0.5413	ACAT2/ACACA/LDHD/PKLR/HAGH/PC	6
KEGG	hsa01212	Fatty acid metabolism	7/697	57/8135	0.213	0.5939	0.5413	ACAT2/ACACA/FADS1/ELOVL7/CPT1C/FADS2/HADH	7
KEGG	hsa05134	Legionellosis	7/697	57/8135	0.213	0.5939	0.5413	TLR4/C3/BNIP3/CASP7/CR1/ITGAM/VCP	7
KEGG	hsa05163	Human cytomegalovirus infection	23/697	225/8135	0.2144	0.5939	0.5413	TAP2/ADCY3/RAC3/EGFR/ADCY1/ROCK1/GNG8/CRKL/HLA-G/GNG3/CDK6/PIK3R1/GNG12/CXCL12/PPP3R1/GNG4/RAF1/PTGER1/PRKCG/AKT2/CHUK/CALML4/PLCB1	23
KEGG	hsa00564	Glycerophospholipid metabolism	11/697	98/8135	0.2162	0.5939	0.5413	LPCAT3/GPAM/AGPAT3/PLD4/PLD3/LPIN2/AGPAT1/DGKZ/PNPLA6/PCYT1A/LPGAT1	11
KEGG	hsa04935	Growth hormone synthesis, secretion and action	13/697	119/8135	0.2178	0.5939	0.5413	ADCY3/SOCS3/ADCY1/SHC3/CRKL/IRS1/PIK3R1/CSH1/RAF1/IGFBP3/PRKCG/AKT2/PLCB1	13
KEGG	hsa00531	Glycosaminoglycan degradation	3/697	19/8135	0.2191	0.5939	0.5413	IDUA/GALNS/HEXA	3
KEGG	hsa05330	Allograft rejection	5/697	38/8135	0.2227	0.5989	0.5458	HLA-DPB1/HLA-G/HLA-DRA/HLA-DOA/HLA-DRB4	5
KEGG	hsa04976	Bile secretion	10/697	89/8135	0.2297	0.6126	0.5583	ADCY3/ADCY1/SCARB1/NR1H4/ATP1A4/SLC9A1/LDLR/RXRA/NCEH1/EPHX1	10
KEGG	hsa04919	Thyroid hormone signaling pathway	13/697	121/8135	0.2355	0.6185	0.5637	ACTG1/PIK3R1/ATP1A4/SLC9A1/MYH6/RXRG/RXRA/WNT4/RAF1/PRKCG/AKT2/PLCB1/FOXO1	13
KEGG	hsa04061	Viral protein interaction with cytokine and cytokine receptor	11/697	100/8135	0.2357	0.6185	0.5637	TNFRSF14/CCL17/CCR8/CXCL12/CCL21/TNFRSF1B/CCL16/IL2RG/IL20RA/TNFRSF10B/CXCL14	11
KEGG	hsa04020	Calcium signaling pathway	24/697	240/8135	0.2408	0.6265	0.571	CYSLTR2/FGF5/CASQ1/NTRK1/NOS3/ADCY3/EDNRB/FGF6/EGFR/ADCY1/P2RX2/CACNA1I/FGF17/TACR3/RYR1/PPP3R1/MCOLN1/AGTR1/CACNA1G/TRHR/PTGER1/PRKCG/CALML4/PLCB1	24
KEGG	hsa00670	One carbon pool by folate	3/697	20/8135	0.2426	0.6265	0.571	MTHFD1/ALDH1L1/ALDH1L2	3
KEGG	hsa04979	Cholesterol metabolism	6/697	50/8135	0.2547	0.6476	0.5902	SCARB1/PCSK9/LDLR/NCEH1/APOA4/APOA1	6
KEGG	hsa05144	Malaria	6/697	50/8135	0.2547	0.6476	0.5902	TGFB1/SDC1/ITGAL/TLR4/CR1/VCAM1	6
KEGG	hsa05171	Coronavirus disease - COVID-19	23/697	232/8135	0.2601	0.6535	0.5957	C1QB/NRP1/C1QA/C1QC/EGFR/RPL28/C3AR1/RPS15A/PIK3R1/TYK2/RPL10/TLR4/C3/IRAK4/RPLP1/MASP1/AGTR1/RPS4Y1/C5AR1/PRKCG/TRAF3/CHUK/CFD	23
KEGG	hsa04150	mTOR signaling pathway	16/697	156/8135	0.261	0.6535	0.5957	IRS1/ATP6V1E1/PIK3R1/LRP5/TELO2/LPIN2/ULK2/DVL1/WNT4/RAF1/FZD5/PRKCG/AKT2/CHUK/FZD10/PRKAA1	16
KEGG	hsa05160	Hepatitis C	16/697	157/8135	0.2694	0.6625	0.6038	SOCS3/EGFR/PPP2CB/SCARB1/CDK6/PIK3R1/TYK2/OCLN/LDLR/PPP2R2D/RXRA/RAF1/TRAF3/CLDN4/AKT2/CHUK	16
KEGG	hsa00330	Arginine and proline metabolism	6/697	51/8135	0.2696	0.6625	0.6038	NOS3/CARNS1/PRODH2/ALDH18A1/LAP3/P4HA2	6
KEGG	hsa03440	Homologous recombination	5/697	41/8135	0.2723	0.6625	0.6038	XRCC2/RAD52/RAD50/POLD2/RPA2	5
KEGG	hsa04912	GnRH signaling pathway	10/697	93/8135	0.2727	0.6625	0.6038	ADCY3/EGFR/ADCY1/MAP3K4/PRKCD/RAF1/CDC42/GNRH2/CALML4/PLCB1	10
KEGG	hsa04625	C-type lectin receptor signaling pathway	11/697	104/8135	0.2766	0.6671	0.608	CCL17/CLEC4D/PIK3R1/PPP3R1/PRKCD/RAF1/AKT2/CHUK/CALML4/MALT1/CLEC4E	11
KEGG	hsa00600	Sphingolipid metabolism	6/697	52/8135	0.2847	0.6772	0.6172	GAL3ST1/GLA/ACER1/NEU3/SGPP2/HEXA	6
KEGG	hsa04115	p53 signaling pathway	8/697	73/8135	0.2862	0.6772	0.6172	ATR/CCNB1/BCL2L1/CDK6/RPRM/IGFBP3/CHEK2/TNFRSF10B	8
KEGG	hsa05332	Graft-versus-host disease	5/697	42/8135	0.2894	0.6772	0.6172	HLA-DPB1/HLA-G/HLA-DRA/HLA-DOA/HLA-DRB4	5
KEGG	hsa00220	Arginine biosynthesis	3/697	22/8135	0.2905	0.6772	0.6172	NOS3/GLUL/ASS1	3
KEGG	hsa05217	Basal cell carcinoma	7/697	63/8135	0.2931	0.6772	0.6172	TCF7L1/DVL1/WNT4/FZD5/SMO/AXIN1/FZD10	7
KEGG	hsa04915	Estrogen signaling pathway	14/697	138/8135	0.2932	0.6772	0.6172	NOS3/ADCY3/EGFR/ADCY1/SHC3/KRT27/PIK3R1/GABBR2/PRKCD/RAF1/AKT2/CALML4/FKBP5/PLCB1	14
KEGG	hsa04261	Adrenergic signaling in cardiomyocytes	15/697	150/8135	0.3033	0.6935	0.6321	ADCY3/ADCY1/PPP2CB/ATP1A4/SLC9A1/PPP1R1A/MYH6/PPP2R2D/AGTR1/PPP2R3B/CACNG1/TNNT2/AKT2/CALML4/PLCB1	15
KEGG	hsa05414	Dilated cardiomyopathy	10/697	96/8135	0.3064	0.6935	0.6321	ITGA4/ADCY3/ITGB4/ADCY1/ACTG1/TGFB1/MYH6/CACNG1/TNNT2/ITGA5	10
KEGG	hsa04940	Type I diabetes mellitus	5/697	43/8135	0.3066	0.6935	0.6321	HLA-DPB1/HLA-G/HLA-DRA/HLA-DOA/HLA-DRB4	5
KEGG	hsa05214	Glioma	8/697	75/8135	0.3121	0.7011	0.639	EGFR/SHC3/CDK6/PIK3R1/RAF1/PRKCG/AKT2/CALML4	8
KEGG	hsa04080	Neuroactive ligand-receptor interaction	33/697	353/8135	0.3234	0.7194	0.6557	CYSLTR2/GALR3/PARD3/FPR2/EDNRB/PRSS2/C3AR1/P2RX2/LYPD6B/TRPV1/RLN1/TACR3/GALR2/MCHR1/C3/GABBR2/GRP/SLURP1/ADORA3/PTH2R/FPR1/AGTR1/PRLR/CSH1/GLRA1/C5AR1/VIPR1/TRHR/PTGER1/P2RY14/GNRH2/PTH1R/UCN3	33
KEGG	hsa04971	Gastric acid secretion	8/697	76/8135	0.3252	0.7194	0.6557	ADCY3/ADCY1/ACTG1/ATP1A4/SLC9A1/PRKCG/CALML4/PLCB1	8
KEGG	hsa05231	Choline metabolism in cancer	10/697	98/8135	0.3294	0.7194	0.6557	PIP5K1A/RAC3/EGFR/SLC44A2/PIK3R1/DGKZ/RAF1/PRKCG/AKT2/PCYT1A	10
KEGG	hsa04066	HIF-1 signaling pathway	11/697	109/8135	0.3305	0.7194	0.6557	NOS3/HK2/EGFR/IFNGR1/PIK3R1/ALDOB/TLR4/HK1/PRKCG/AKT2/NPPA	11
KEGG	hsa04068	FoxO signaling pathway	13/697	131/8135	0.3312	0.7194	0.6557	EGFR/PLK2/TGFB1/CCNB1/IRS1/PIK3R1/BNIP3/TGFBR2/RAF1/AKT2/CHUK/PRKAA1/FOXO1	13
KEGG	hsa04720	Long-term potentiation	7/697	67/8135	0.3498	0.7459	0.6798	ADCY1/PPP3R1/PPP1R1A/RAF1/PRKCG/CALML4/PLCB1	7
KEGG	hsa05221	Acute myeloid leukemia	7/697	67/8135	0.3498	0.7459	0.6798	PIM1/TCF7L1/PIK3R1/RAF1/ITGAM/AKT2/CHUK	7
KEGG	hsa04727	GABAergic synapse	9/697	89/8135	0.3525	0.7459	0.6798	ADCY3/ADCY1/GNG8/GNG3/GLUL/GNG12/GNG4/GABBR2/PRKCG	9
KEGG	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	9/697	89/8135	0.3525	0.7459	0.6798	BATF3/EGFR/IFNGR1/PIK3R1/TLR4/PPP3R1/RAF1/AKT2/CHUK	9
KEGG	hsa04310	Wnt signaling pathway	16/697	167/8135	0.3573	0.7513	0.6848	LGR4/RAC3/TCF7L1/LRP5/PPP3R1/DVL1/WNT4/NKD1/FZD5/PRKCG/AXIN1/NKD2/FZD10/VANGL2/CTNND2/PLCB1	16
KEGG	hsa05410	Hypertrophic cardiomyopathy	9/697	90/8135	0.365	0.7585	0.6913	ITGA4/ITGB4/ACTG1/TGFB1/MYH6/CACNG1/TNNT2/ITGA5/PRKAA1	9
KEGG	hsa05169	Epstein-Barr virus infection	19/697	202/8135	0.3693	0.7585	0.6913	HLA-DPB1/TAP2/BTK/HLA-G/CDK6/PIK3R1/RUNX3/ITGAL/TYK2/IRAK4/PSMD7/HLA-DRA/TRAF3/HLA-DOA/AKT2/CHUK/PSMD12/PSMC4/HLA-DRB4	19
KEGG	hsa04725	Cholinergic synapse	11/697	113/8135	0.3749	0.7585	0.6913	ADCY3/ADCY1/GNG8/GNG3/PIK3R1/GNG12/GNG4/PRKCG/AKT2/KCNJ4/PLCB1	11
KEGG	hsa04972	Pancreatic secretion	10/697	102/8135	0.3763	0.7585	0.6913	ADCY3/CELA3B/ADCY1/PRSS2/BST1/ATP1A4/SLC9A1/PNLIPRP2/PRKCG/PLCB1	10
KEGG	hsa03420	Nucleotide excision repair	5/697	47/8135	0.3765	0.7585	0.6913	RFC5/XPC/POLD2/DDB1/RPA2	5
KEGG	hsa05213	Endometrial cancer	6/697	58/8135	0.3782	0.7585	0.6913	EGFR/TCF7L1/PIK3R1/RAF1/AXIN1/AKT2	6
KEGG	hsa04210	Apoptosis	13/697	136/8135	0.382	0.7585	0.6913	NTRK1/ACTG1/BCL2L1/CASP2/PIK3R1/CTSH/CAPN1/RAF1/CASP7/AKT2/CHUK/TNFRSF10B/LMNB2	13
KEGG	hsa05417	Lipid and atherosclerosis	20/697	215/8135	0.3835	0.7585	0.6913	NOS3/BCL2L1/PIK3R1/TLR4/PPP3R1/IRAK4/LDLR/RXRG/RXRA/CASP7/TRAF3/APOA4/CDC42/AKT2/CHUK/VCAM1/CALML4/TNFRSF10B/APOA1/PLCB1	20
KEGG	hsa05132	Salmonella infection	23/697	249/8135	0.3837	0.7585	0.6913	MYO6/ACTR1B/ACTG1/MYL9/DNM2/TCF7L1/ACTR3B/TLR4/KIF5C/IRAK4/CYFIP2/DYNC2LI1/DYNLL2/ARPC5/RAF1/CASP7/CDC42/AKT2/CHUK/KLC4/TNFRSF10B/RAB5C/CASP5	23
KEGG	hsa05202	Transcriptional misregulation in cancer	18/697	193/8135	0.3886	0.7585	0.6913	MAF/NTRK1/HPGD/LDB1/BCL2L1/NUPR1/NGFR/TLX1/ERG/RXRG/RXRA/TCF3/TGFBR2/MITF/IGFBP3/ITGAM/FOXO1/SMAD1	18
KEGG	hsa04072	Phospholipase D signaling pathway	14/697	148/8135	0.3898	0.7585	0.6913	PIP5K1A/ADCY3/EGFR/ADCY1/DNM2/SHC3/AGPAT3/PIK3R1/AGPAT1/AGTR1/DGKZ/RAF1/AKT2/PLCB1	14
KEGG	hsa00250	Alanine, aspartate and glutamate metabolism	4/697	37/8135	0.3925	0.7585	0.6913	ASNS/GLUL/PPAT/ASS1	4
KEGG	hsa05216	Thyroid cancer	4/697	37/8135	0.3925	0.7585	0.6913	NTRK1/TCF7L1/RXRG/RXRA	4
KEGG	hsa05230	Central carbon metabolism in cancer	7/697	70/8135	0.3931	0.7585	0.6913	NTRK1/HK2/EGFR/PIK3R1/HK1/RAF1/AKT2	7
KEGG	hsa05167	Kaposi sarcoma-associated herpesvirus infection	18/697	194/8135	0.3973	0.7621	0.6946	IFNGR1/GNG8/CCR8/TCF7L1/HLA-G/GNG3/CDK6/PIK3R1/GNG12/TYK2/C3/PPP3R1/GNG4/RAF1/TRAF3/AKT2/CHUK/CALML4	18
KEGG	hsa00360	Phenylalanine metabolism	2/697	16/8135	0.4039	0.7702	0.702	PAH/ALDH3B1	2
KEGG	hsa01040	Biosynthesis of unsaturated fatty acids	3/697	27/8135	0.4112	0.7775	0.7086	FADS1/ELOVL7/FADS2	3
KEGG	hsa05340	Primary immunodeficiency	4/697	38/8135	0.4124	0.7775	0.7086	TAP2/ADA/BTK/IL2RG	4
KEGG	hsa05130	Pathogenic Escherichia coli infection	18/697	197/8135	0.4234	0.793	0.7227	BAIAP2/MYO6/ROCK1/ACTG1/ACTR3B/TLR4/OCLN/IRAK4/CYFIP2/MYH14/ARPC5/SLC9A3R1/CASP7/MYO5A/CLDN4/CDC42/CHUK/TNFRSF10B	18
KEGG	hsa00590	Arachidonic acid metabolism	6/697	61/8135	0.4255	0.793	0.7227	AKR1C3/LTC4S/ALOX15B/CYP2U1/LTA4H/CBR3	6
KEGG	hsa00120	Primary bile acid biosynthesis	2/697	17/8135	0.4346	0.7934	0.7232	CH25H/AKR1D1	2
KEGG	hsa00910	Nitrogen metabolism	2/697	17/8135	0.4346	0.7934	0.7232	GLUL/CA12	2
KEGG	hsa00650	Butanoate metabolism	3/697	28/8135	0.4348	0.7934	0.7232	ACAT2/HMGCLL1/HADH	3
KEGG	hsa01524	Platinum drug resistance	7/697	73/8135	0.4364	0.7934	0.7232	MSH6/MSH2/BCL2L1/PIK3R1/ATP7A/GSTT1/AKT2	7
KEGG	hsa01232	Nucleotide metabolism	8/697	85/8135	0.4453	0.7934	0.7232	AMPD2/ADA/HDDC2/XDH/DUT/NME3/CDA/RRM1	8
KEGG	hsa04012	ErbB signaling pathway	8/697	85/8135	0.4453	0.7934	0.7232	EGFR/AREG/SHC3/CRKL/PIK3R1/RAF1/PRKCG/AKT2	8
KEGG	hsa00270	Cysteine and methionine metabolism	5/697	51/8135	0.4463	0.7934	0.7232	CBS/MAT2A/DNMT1/MAT1A/AHCY	5
KEGG	hsa04913	Ovarian steroidogenesis	5/697	51/8135	0.4463	0.7934	0.7232	AKR1C3/ADCY3/ADCY1/SCARB1/LDLR	5
KEGG	hsa04931	Insulin resistance	10/697	108/8135	0.4475	0.7934	0.7232	PRKCE/NOS3/SOCS3/IRS1/PPP1R3E/PIK3R1/PRKCD/AKT2/PRKAA1/FOXO1	10
KEGG	hsa04152	AMPK signaling pathway	11/697	120/8135	0.4538	0.7968	0.7262	PPP2CB/ACACA/IRS1/PIK3R1/CPT1C/PPP2R2D/CAMKK2/PPP2R3B/AKT2/PRKAA1/FOXO1	11
KEGG	hsa04550	Signaling pathways regulating pluripotency of stem cells	13/697	143/8135	0.4543	0.7968	0.7262	POU5F1B/HOXB1/PIK3R1/DVL1/TCF3/WNT4/RAF1/FZD5/AXIN1/AKT2/FZD10/OTX1/SMAD1	13
KEGG	hsa04142	Lysosome	12/697	132/8135	0.4595	0.8016	0.7306	AGA/AP3S2/LAPTM4B/TCIRG1/GLA/CTNS/IDUA/CTSH/GALNS/MCOLN1/HEXA/AP3M2	12
KEGG	hsa04613	Neutrophil extracellular trap formation	17/697	190/8135	0.4631	0.8017	0.7307	FPR2/ACTG1/PIK3R1/HDAC8/ITGAL/TLR4/C3/HDAC11/FPR1/ATG7/RAF1/C5AR1/PRKCG/CR1/ITGAM/AKT2/PLCB1	17
KEGG	hsa00061	Fatty acid biosynthesis	2/697	18/8135	0.4644	0.8017	0.7307	ACACA/OLAH	2
KEGG	hsa04961	Endocrine and other factor-regulated calcium reabsorption	5/697	53/8135	0.4805	0.8087	0.7371	DNM2/ATP1A4/PRKCG/PTH1R/PLCB1	5
KEGG	hsa05320	Autoimmune thyroid disease	5/697	53/8135	0.4805	0.8087	0.7371	HLA-DPB1/HLA-G/HLA-DRA/HLA-DOA/HLA-DRB4	5
KEGG	hsa00030	Pentose phosphate pathway	3/697	30/8135	0.4808	0.8087	0.7371	ALDOB/TKT/RPIA	3
KEGG	hsa00630	Glyoxylate and dicarboxylate metabolism	3/697	30/8135	0.4808	0.8087	0.7371	ACAT2/HYI/GLUL	3
KEGG	hsa01523	Antifolate resistance	3/697	30/8135	0.4808	0.8087	0.7371	ABCC5/CHUK/FOLR1	3
KEGG	hsa04540	Gap junction	8/697	88/8135	0.4851	0.8109	0.7391	ADCY3/EGFR/ADCY1/GJA1/MAP2K5/RAF1/PRKCG/PLCB1	8
KEGG	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	7/697	77/8135	0.4933	0.8109	0.7391	ITGA4/ITGB4/ACTG1/TCF7L1/GJA1/CACNG1/ITGA5	7
KEGG	hsa04211	Longevity regulating pathway	8/697	89/8135	0.4982	0.8109	0.7391	ADCY3/ADCY1/IRS1/PIK3R1/CAMKK2/AKT2/PRKAA1/FOXO1	8
KEGG	hsa04611	Platelet activation	11/697	124/8135	0.4985	0.8109	0.7391	NOS3/ADCY3/ADCY1/ROCK1/ACTG1/BTK/PIK3R1/COL1A2/AKT2/GP9/PLCB1	11
KEGG	hsa04141	Protein processing in endoplasmic reticulum	15/697	171/8135	0.5019	0.8109	0.7391	DNAJB2/STT3B/UBXN2A/DNAJC5G/HYOU1/DNAJC10/HSPH1/MAN1C1/DNAJC5B/SEC31B/TRAM1/UGGT1/CAPN1/DERL3/VCP	15
KEGG	hsa00052	Galactose metabolism	3/697	31/8135	0.5031	0.8109	0.7391	HK2/GLA/HK1	3
KEGG	hsa04710	Circadian rhythm	3/697	31/8135	0.5031	0.8109	0.7391	FBXL3/CLOCK/PRKAA1	3
KEGG	hsa04612	Antigen processing and presentation	7/697	78/8135	0.5073	0.8109	0.7391	HLA-DPB1/TAP2/KLRC4/HLA-G/HLA-DRA/HLA-DOA/HLA-DRB4	7
KEGG	hsa04721	Synaptic vesicle cycle	7/697	78/8135	0.5073	0.8109	0.7391	SLC18A1/TCIRG1/SLC17A8/DNM2/ATP6V1E1/SLC1A7/SLC6A7	7
KEGG	hsa00071	Fatty acid degradation	4/697	43/8135	0.5093	0.8109	0.7391	CYP2U1/ACAT2/CPT1C/HADH	4
KEGG	hsa00860	Porphyrin metabolism	4/697	43/8135	0.5093	0.8109	0.7391	CP/ALAS1/HMOX2/FXN	4
KEGG	hsa04914	Progesterone-mediated oocyte maturation	9/697	102/8135	0.5146	0.8139	0.7418	ADCY3/ANAPC1/ADCY1/CCNB1/ANAPC13/PIK3R1/PKMYT1/RAF1/AKT2	9
KEGG	hsa04110	Cell cycle	11/697	126/8135	0.5205	0.8139	0.7418	CDKN1C/ANAPC1/ATR/TGFB1/CCNB1/CDC45/ANAPC13/CDK6/MCM5/PKMYT1/CHEK2	11
KEGG	hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	2/697	20/8135	0.5211	0.8139	0.7418	CHST7/B3GALT6	2
KEGG	hsa01521	EGFR tyrosine kinase inhibitor resistance	7/697	79/8135	0.5211	0.8139	0.7418	EGFR/SHC3/BCL2L1/PIK3R1/RAF1/PRKCG/AKT2	7
KEGG	hsa04215	Apoptosis - multiple species	3/697	32/8135	0.5249	0.816	0.7437	BCL2L1/NGFR/CASP7	3
KEGG	hsa04726	Serotonergic synapse	10/697	115/8135	0.5292	0.8187	0.7462	SLC18A1/ALOX15B/GNG8/GNG3/GNG12/HTR3C/GNG4/RAF1/PRKCG/PLCB1	10
KEGG	hsa04130	SNARE interactions in vesicular transport	3/697	33/8135	0.5462	0.8312	0.7575	BET1L/GOSR2/STX8	3
KEGG	hsa04924	Renin secretion	6/697	69/8135	0.5473	0.8312	0.7575	PPP3R1/AGTR1/NPR1/CALML4/NPPA/PLCB1	6
KEGG	hsa05031	Amphetamine addiction	6/697	69/8135	0.5473	0.8312	0.7575	SLC18A1/PPP3R1/TH/PRKCG/CALML4/ARC	6
KEGG	hsa05211	Renal cell carcinoma	6/697	69/8135	0.5473	0.8312	0.7575	TGFB1/CRKL/PIK3R1/RAF1/CDC42/AKT2	6
KEGG	hsa04146	Peroxisome	7/697	82/8135	0.5617	0.838	0.7638	PECR/XDH/MPV17L/HMGCLL1/PEX19/SOD1/ABCD2	7
KEGG	hsa04350	TGF-beta signaling pathway	8/697	94/8135	0.5619	0.838	0.7638	NEO1/LTBP1/ROCK1/TGFB1/PPP2CB/TGFBR2/ZFYVE9/SMAD1	8
KEGG	hsa04657	IL-17 signaling pathway	8/697	94/8135	0.5619	0.838	0.7638	IL17B/CCL17/IL17RC/MUC5AC/IL17A/JUND/TRAF3/CHUK	8
KEGG	hsa00240	Pyrimidine metabolism	5/697	58/8135	0.5624	0.838	0.7638	HDDC2/DUT/NME3/CDA/RRM1	5
KEGG	hsa00340	Histidine metabolism	2/697	22/8135	0.5736	0.838	0.7638	CARNS1/ALDH3B1	2
KEGG	hsa00900	Terpenoid backbone biosynthesis	2/697	22/8135	0.5736	0.838	0.7638	ACAT2/IDI2	2
KEGG	hsa04650	Natural killer cell mediated cytotoxicity	11/697	131/8135	0.5741	0.838	0.7638	RAC3/IFNGR1/SHC3/HLA-G/PIK3R1/ITGAL/PPP3R1/SH2D1B/RAF1/PRKCG/TNFRSF10B	11
KEGG	hsa05017	Spinocerebellar ataxia	12/697	143/8135	0.5744	0.838	0.7638	PIK3R1/RYR1/ULK2/SPTBN2/PSMD7/ATG2A/PRKCG/AKT2/KCND3/PSMD12/PSMC4/PLCB1	12
KEGG	hsa04932	Non-alcoholic fatty liver disease	13/697	155/8135	0.5748	0.838	0.7638	SOCS3/TGFB1/IRS1/PIK3R1/NDUFV3/PKLR/NDUFB2/COX6B2/RXRA/CASP7/CDC42/AKT2/PRKAA1	13
KEGG	hsa00514	Other types of O-glycan biosynthesis	4/697	47/8135	0.5813	0.8436	0.7689	GALNT2/ST3GAL3/GALNT11/POMT2	4
KEGG	hsa03013	Nucleocytoplasmic transport	9/697	108/8135	0.5855	0.846	0.7711	NUP205/IPO5/THOC5/THOC1/NCBP1/NUP155/KPNB1/IPO7/IPO9	9
KEGG	hsa04730	Long-term depression	5/697	60/8135	0.5933	0.8534	0.7779	PPP2CB/RYR1/RAF1/PRKCG/PLCB1	5
KEGG	hsa00280	Valine, leucine and isoleucine degradation	4/697	48/8135	0.5983	0.8534	0.7779	ACAT2/HMGCLL1/HADH/HIBADH	4
KEGG	hsa05215	Prostate cancer	8/697	97/8135	0.5985	0.8534	0.7779	EGFR/TCF7L1/PIK3R1/ERG/RAF1/AKT2/CHUK/FOXO1	8
KEGG	hsa00562	Inositol phosphate metabolism	6/697	73/8135	0.6038	0.8539	0.7782	PIP5K1A/OCRL/INPP5F/INPP5E/PLCB1/IPPK	6
KEGG	hsa00350	Tyrosine metabolism	3/697	36/8135	0.6066	0.8539	0.7782	TYR/TH/ALDH3B1	3
KEGG	hsa00760	Nicotinate and nicotinamide metabolism	3/697	36/8135	0.6066	0.8539	0.7782	NNMT/BST1/QPRT	3
KEGG	hsa01522	Endocrine resistance	8/697	98/8135	0.6103	0.8546	0.7789	ADCY3/EGFR/ADCY1/SHC3/PIK3R1/DLL3/RAF1/AKT2	8
KEGG	hsa04911	Insulin secretion	7/697	86/8135	0.6133	0.8546	0.7789	ADCY3/ADCY1/KCNN1/ABCC8/ATP1A4/PRKCG/PLCB1	7
KEGG	hsa00565	Ether lipid metabolism	4/697	49/8135	0.6149	0.8546	0.7789	GAL3ST1/PAFAH2/PLD4/PLD3	4
KEGG	hsa00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	2/697	24/8135	0.6219	0.8553	0.7796	B3GALT6/EXTL1	2
KEGG	hsa04024	cAMP signaling pathway	18/697	221/8135	0.6259	0.8553	0.7796	ARAP3/ADCY3/RAC3/ADCY1/ROCK1/MYL9/PIK3R1/ATP1A4/SLC9A1/GABBR2/PDE4C/HCN2/NPR1/RAF1/AKT2/CALML4/NPPA/CNGA4	18
KEGG	hsa00130	Ubiquinone and other terpenoid-quinone biosynthesis	1/697	11/8135	0.6269	0.8553	0.7796	NQO1	1
KEGG	hsa03320	PPAR signaling pathway	6/697	75/8135	0.6306	0.8553	0.7796	FABP6/CPT1C/FADS2/RXRG/RXRA/APOA1	6
KEGG	hsa00510	N-Glycan biosynthesis	4/697	50/8135	0.6311	0.8553	0.7796	STT3B/MAN1C1/MGAT3/MGAT4C	4
KEGG	hsa05110	Vibrio cholerae infection	4/697	50/8135	0.6311	0.8553	0.7796	ADCY3/TCIRG1/ACTG1/ATP6V1E1	4
KEGG	hsa05207	Chemical carcinogenesis - receptor activation	17/697	212/8135	0.6503	0.8777	0.8	FGF5/MIRLET7D/ADCY3/FGF6/EGFR/ADCY1/FGF17/PIK3R1/GSTT1/DLL3/KPNB1/RXRG/RXRA/RAF1/PRKCG/AKT2/EPHX1	17
KEGG	hsa05162	Measles	11/697	139/8135	0.6541	0.8793	0.8014	FCGR2B/BCL2L1/CDK6/PIK3R1/TYK2/TLR4/IRAK4/IL2RG/TRAF3/AKT2/CHUK	11
KEGG	hsa04950	Maturity onset diabetes of the young	2/697	26/8135	0.6657	0.8913	0.8123	PKLR/NKX6-1	2
KEGG	hsa00970	Aminoacyl-tRNA biosynthesis	5/697	66/8135	0.6782	0.897	0.8176	SARS2/FARS2/LARS2/NARS2/VARS2	5
KEGG	hsa00260	Glycine, serine and threonine metabolism	3/697	40/8135	0.6783	0.897	0.8176	GCAT/ALAS1/CBS	3
KEGG	hsa03018	RNA degradation	6/697	79/8135	0.6808	0.897	0.8176	EDC4/EXOSC1/TOB1/DIS3L/CNOT10/PAN2	6
KEGG	hsa00062	Fatty acid elongation	2/697	27/8135	0.6861	0.897	0.8176	ELOVL7/HADH	2
KEGG	hsa04966	Collecting duct acid secretion	2/697	27/8135	0.6861	0.897	0.8176	TCIRG1/ATP6V1E1	2
KEGG	hsa00010	Glycolysis / Gluconeogenesis	5/697	67/8135	0.6911	0.897	0.8176	HK2/ALDOB/PKLR/HK1/ALDH3B1	5
KEGG	hsa03460	Fanconi anemia pathway	4/697	54/8135	0.6913	0.897	0.8176	ATR/TELO2/RPA2/FANCF	4
KEGG	hsa00983	Drug metabolism - other enzymes	6/697	80/8135	0.6926	0.897	0.8176	XDH/DUT/NME3/CDA/GSTT1/RRM1	6
KEGG	hsa04216	Ferroptosis	3/697	41/8135	0.6947	0.897	0.8176	LPCAT3/CP/ATG7	3
KEGG	hsa04664	Fc epsilon RI signaling pathway	5/697	68/8135	0.7037	0.9051	0.8249	RAC3/BTK/PIK3R1/RAF1/AKT2	5
KEGG	hsa04922	Glucagon signaling pathway	8/697	107/8135	0.708	0.9071	0.8267	ACACA/PPP3R1/CPT1C/AKT2/CALML4/PRKAA1/PLCB1/FOXO1	8
KEGG	hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	1/697	14/8135	0.7149	0.9125	0.8316	ST3GAL3	1
KEGG	hsa04340	Hedgehog signaling pathway	4/697	56/8135	0.7186	0.9136	0.8327	CSNK1G2/KIF3A/MEGF8/SMO	4
KEGG	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	5/697	70/8135	0.7277	0.921	0.8394	EGFR/TCIRG1/ATP6V1E1/CDC42/CHUK	5
KEGG	hsa05208	Chemical carcinogenesis - reactive oxygen species	17/697	223/8135	0.73	0.921	0.8394	AKR1C3/AKR1C2/EGFR/PIK3R1/NDUFV3/NDUFB2/GSTT1/LPO/COX6B2/PRKCD/SLC26A2/RAF1/NQO1/AKT2/CHUK/SOD1/EPHX1	17
KEGG	hsa04723	Retrograde endocannabinoid signaling	11/697	148/8135	0.7332	0.921	0.8395	ADCY3/ADCY1/SLC17A8/GNG8/GNG3/NDUFV3/GNG12/NDUFB2/GNG4/PRKCG/PLCB1	11
KEGG	hsa00604	Glycosphingolipid biosynthesis - ganglio series	1/697	15/8135	0.7394	0.921	0.8395	HEXA	1
KEGG	hsa00730	Thiamine metabolism	1/697	15/8135	0.7394	0.921	0.8395	TPK1	1
KEGG	hsa05161	Hepatitis B	12/697	162/8135	0.7434	0.921	0.8395	TGFB1/PIK3R1/TYK2/TLR4/IRAK4/TGFBR2/RAF1/PRKCG/DDB1/TRAF3/AKT2/CHUK	12
KEGG	hsa00480	Glutathione metabolism	4/697	58/8135	0.7441	0.921	0.8395	CHAC2/GSTT1/LAP3/RRM1	4
KEGG	hsa04137	Mitophagy - animal	5/697	72/8135	0.7504	0.9253	0.8433	BCL2L1/RHOT2/BNIP3/MITF/SQSTM1	5
KEGG	hsa04668	TNF signaling pathway	8/697	112/8135	0.7547	0.9254	0.8434	SOCS3/PIK3R1/TNFRSF1B/CASP7/TRAF3/AKT2/CHUK/VCAM1	8
KEGG	hsa00410	beta-Alanine metabolism	2/697	31/8135	0.7575	0.9254	0.8434	CARNS1/ALDH3B1	2
KEGG	hsa00430	Taurine and hypotaurine metabolism	1/697	16/8135	0.7618	0.9254	0.8434	FMO4	1
KEGG	hsa03050	Proteasome	3/697	46/8135	0.767	0.9254	0.8434	PSMD7/PSMD12/PSMC4	3
KEGG	hsa04260	Cardiac muscle contraction	6/697	87/8135	0.7671	0.9254	0.8434	ATP1A4/SLC9A1/COX6B2/MYH6/CACNG1/TNNT2	6
KEGG	hsa04978	Mineral absorption	4/697	60/8135	0.7679	0.9254	0.8434	SLC30A1/ATP1A4/ATP7A/HMOX2	4
KEGG	hsa01240	Biosynthesis of cofactors	11/697	153/8135	0.7717	0.9254	0.8434	PDXK/MTHFD1/PMM2/GMPPB/NME3/ALAS1/QPRT/MAT2A/MAT1A/NQO1/TPK1	11
KEGG	hsa00640	Propanoate metabolism	2/697	32/8135	0.773	0.9254	0.8434	ACACA/ACSS3	2
KEGG	hsa01200	Carbon metabolism	8/697	115/8135	0.7801	0.9289	0.8466	HK2/ACAT2/ALDOB/TKT/PKLR/RPIA/HK1/PC	8
KEGG	hsa04918	Thyroid hormone synthesis	5/697	75/8135	0.7816	0.9289	0.8466	ADCY3/ADCY1/ATP1A4/PRKCG/PLCB1	5
KEGG	hsa04660	T cell receptor signaling pathway	7/697	104/8135	0.7989	0.9422	0.8588	PIK3R1/PPP3R1/RAF1/CDC42/AKT2/CHUK/MALT1	7
KEGG	hsa04114	Oocyte meiosis	9/697	131/8135	0.8014	0.9422	0.8588	ADCY3/ANAPC1/ADCY1/PPP2CB/CCNB1/ANAPC13/PPP3R1/PKMYT1/CALML4	9
KEGG	hsa03020	RNA polymerase	2/697	34/8135	0.8015	0.9422	0.8588	POLR1E/POLR2I	2
KEGG	hsa00980	Metabolism of xenobiotics by cytochrome P450	5/697	78/8135	0.8098	0.9486	0.8646	AKR7A3/GSTT1/CBR3/EPHX1/ALDH3B1	5
KEGG	hsa05022	Pathways of neurodegeneration - multiple diseases	36/697	476/8135	0.8127	0.9486	0.8646	NEFH/ACTR1B/BCL2L1/NDUFV3/LRP5/RYR1/TOMM40L/NDUFB2/PPP3R1/KIF5C/ULK2/SPTBN2/COX6B2/WDR41/CAPN1/TNFRSF1B/DNAH10/DVL1/WNT4/PSMD7/RAF1/CASP7/DNAH5/ATG2A/FZD5/SQSTM1/PRKCG/AXIN1/FZD10/SOD1/CALML4/KLC4/PSMD12/PSMC4/VCP/PLCB1	36
KEGG	hsa05034	Alcoholism	13/697	187/8135	0.8231	0.9548	0.8702	SLC18A1/GNG8/SHC3/SLC29A2/GNG3/HDAC8/GNG12/GNG4/HDAC11/CAMKK2/RAF1/TH/CALML4	13
KEGG	hsa00500	Starch and sucrose metabolism	2/697	36/8135	0.8267	0.9548	0.8702	HK2/HK1	2
KEGG	hsa00512	Mucin type O-glycan biosynthesis	2/697	36/8135	0.8267	0.9548	0.8702	GALNT2/GALNT11	2
KEGG	hsa00100	Steroid biosynthesis	1/697	20/8135	0.8337	0.959	0.8741	LSS	1
KEGG	hsa05415	Diabetic cardiomyopathy	14/697	203/8135	0.8388	0.959	0.8741	NOS3/TGFB1/IRS1/PIK3R1/NDUFV3/NDUFB2/COX6B2/PRKCD/COL1A2/AGTR1/TGFBR2/PRKCG/AKT2/PLCB1	14
KEGG	hsa05010	Alzheimer disease	28/697	384/8135	0.8438	0.959	0.8741	SLC39A5/IRS1/PIK3R1/NDUFV3/LRP5/NDUFB2/PPP3R1/KIF5C/ULK2/COX6B2/CAPN1/SLC39A2/DVL1/WNT4/PSMD7/RAF1/CASP7/ATG2A/FZD5/AXIN1/AKT2/CHUK/FZD10/CALML4/KLC4/PSMD12/PSMC4/PLCB1	28
KEGG	hsa05203	Viral carcinogenesis	14/697	204/8135	0.8438	0.959	0.8741	CCR8/HPN/HLA-G/CDK6/PIK3R1/HDAC8/C3/GTF2A1/HDAC11/POLB/SCRIB/DDB1/TRAF3/CDC42	14
KEGG	hsa00830	Retinol metabolism	4/697	68/8135	0.8458	0.959	0.8741	CYP26B1/CYP2W1/RDH8/DGAT1	4
KEGG	hsa00770	Pantothenate and CoA biosynthesis	1/697	21/8135	0.8479	0.959	0.8741	VNN1	1
KEGG	hsa05014	Amyotrophic lateral sclerosis	26/697	364/8135	0.8634	0.9706	0.8846	NEFH/ACTR1B/ACTG1/NUP205/BCL2L1/NDUFV3/TOMM40L/NCBP1/NUP155/NDUFB2/PPP3R1/KIF5C/ULK2/COX6B2/WDR41/TNFRSF1B/DNAH10/PSMD7/DNAH5/ATG2A/SQSTM1/SOD1/KLC4/PSMD12/PSMC4/VCP	26
KEGG	hsa04742	Taste transduction	5/697	86/8135	0.8709	0.9706	0.8846	P2RX2/HTR3C/GABBR2/TAS2R38/PLCB1	5
KEGG	hsa03060	Protein export	1/697	23/8135	0.8729	0.9706	0.8846	IMMP2L	1
KEGG	hsa04614	Renin-angiotensin system	1/697	23/8135	0.8729	0.9706	0.8846	AGTR1	1
KEGG	hsa04964	Proximal tubule bicarbonate reclamation	1/697	23/8135	0.8729	0.9706	0.8846	ATP1A4	1
KEGG	hsa05219	Bladder cancer	2/697	41/8135	0.8776	0.9725	0.8863	EGFR/RAF1	2
KEGG	hsa00380	Tryptophan metabolism	2/697	42/8135	0.886	0.974	0.8877	ACAT2/HADH	2
KEGG	hsa04620	Toll-like receptor signaling pathway	6/697	104/8135	0.8911	0.974	0.8877	PIK3R1/TLR4/IRAK4/TRAF3/AKT2/CHUK	6
KEGG	hsa04330	Notch signaling pathway	3/697	59/8135	0.8916	0.974	0.8877	DTX3/DLL3/DVL1	3
KEGG	hsa03040	Spliceosome	9/697	147/8135	0.8931	0.974	0.8877	RBM25/BCAS2/PHF5A/THOC1/RBMX/SF3A1/NCBP1/SF3A2/SF3B2	9
KEGG	hsa00592	alpha-Linolenic acid metabolism	1/697	25/8135	0.8938	0.974	0.8877	FADS2	1
KEGG	hsa00140	Steroid hormone biosynthesis	3/697	61/8135	0.9043	0.9811	0.8942	AKR1C3/AKR1C2/AKR1D1	3
KEGG	hsa05322	Systemic lupus erythematosus	8/697	136/8135	0.9063	0.9811	0.8942	C1QB/C1QA/C1QC/HLA-DPB1/C3/HLA-DRA/HLA-DOA/HLA-DRB4	8
KEGG	hsa04621	NOD-like receptor signaling pathway	11/697	184/8135	0.9259	0.9896	0.9019	BCL2L1/TRPV2/TYK2/TLR4/IRAK4/PRKCD/TRAF3/PYDC1/CHUK/PLCB1/CASP5	11
KEGG	hsa04392	Hippo signaling pathway - multiple species	1/697	29/8135	0.9259	0.9896	0.9019	WWTR1	1
KEGG	hsa04744	Phototransduction	1/697	29/8135	0.9259	0.9896	0.9019	CALML4	1
KEGG	hsa03015	mRNA surveillance pathway	5/697	97/8135	0.9271	0.9896	0.9019	PPP2CB/NCBP1/SSU72/PPP2R2D/PPP2R3B	5
KEGG	hsa05030	Cocaine addiction	2/697	49/8135	0.9312	0.9896	0.9019	SLC18A1/TH	2
KEGG	hsa00020	Citrate cycle (TCA cycle)	1/697	30/8135	0.9323	0.9896	0.9019	PC	1
KEGG	hsa05204	Chemical carcinogenesis - DNA adducts	3/697	69/8135	0.9427	0.9951	0.9069	AKR1C2/GSTT1/EPHX1	3
KEGG	hsa00982	Drug metabolism - cytochrome P450	3/697	72/8135	0.9529	0.9951	0.9069	GSTT1/FMO4/ALDH3B1	3
KEGG	hsa05020	Prion disease	16/697	273/8135	0.9645	0.9951	0.9069	C1QB/C1QA/C1QC/PIK3R1/NDUFV3/RYR1/NDUFB2/PPP3R1/KIF5C/COX6B2/PRKCD/PSMD7/SOD1/KLC4/PSMD12/PSMC4	16
KEGG	hsa04120	Ubiquitin mediated proteolysis	7/697	142/8135	0.9655	0.9951	0.9069	ANAPC1/HUWE1/SOCS3/ANAPC13/RHOBTB1/DDB1/HERC4	7
KEGG	hsa04714	Thermogenesis	13/697	232/8135	0.9669	0.9951	0.9069	ADCY3/ADCY1/ACTG1/NPPB/NDUFV3/NDUFB2/COX6B2/CPT1C/NPR1/KDM1A/SMARCA4/PRKAA1/NPPA	13
KEGG	hsa04217	Necroptosis	8/697	159/8135	0.9683	0.9951	0.9069	IFNGR1/GLUL/TYK2/TLR4/CAPN1/SQSTM1/IL33/TNFRSF10B	8
KEGG	hsa05033	Nicotine addiction	1/697	40/8135	0.9725	0.9951	0.9069	SLC17A8	1
KEGG	hsa05012	Parkinson disease	15/697	266/8135	0.9733	0.9951	0.9069	SLC18A1/SLC39A5/BCL2L1/NDUFV3/NDUFB2/KIF5C/COX6B2/SLC39A2/PSMD7/TH/SOD1/CALML4/KLC4/PSMD12/PSMC4	15
KEGG	hsa00310	Lysine degradation	2/697	63/8135	0.9759	0.9951	0.9069	ACAT2/HADH	2
KEGG	hsa03250	Viral life cycle - HIV-1	2/697	63/8135	0.9759	0.9951	0.9069	MAP1A/APOBEC3F	2
KEGG	hsa04623	Cytosolic DNA-sensing pathway	2/697	63/8135	0.9759	0.9951	0.9069	IL33/CHUK	2
KEGG	hsa00190	Oxidative phosphorylation	6/697	134/8135	0.9774	0.9951	0.9069	TCIRG1/ATP6V1E1/NDUFV3/NDUFB2/COX6B2/PPA2	6
KEGG	hsa03022	Basal transcription factors	1/697	45/8135	0.9824	0.9951	0.9069	GTF2A1	1
KEGG	hsa05016	Huntington disease	17/697	306/8135	0.9832	0.9951	0.9069	TFAM/ACTR1B/NDUFV3/NDUFB2/KIF5C/ULK2/COX6B2/DNAH10/PSMD7/DNAH5/ATG2A/POLR2I/SOD1/KLC4/PSMD12/PSMC4/PLCB1	17
KEGG	hsa03010	Ribosome	7/697	158/8135	0.9854	0.9951	0.9069	RPL28/RPS15A/MRPL14/RPL10/RPLP1/RPS4Y1/MRPL28	7
KEGG	hsa04622	RIG-I-like receptor signaling pathway	2/697	70/8135	0.986	0.9951	0.9069	TRAF3/CHUK	2
KEGG	hsa05206	MicroRNAs in cancer	16/697	310/8135	0.9925	0.9985	0.9101	PRKCE/MIRLET7D/EGFR/ROCK1/TNN/PIM1/CRKL/IRS1/CDK6/PIK3R1/DNMT1/RAF1/SPRY2/PRKCG/ITGA5/TNR	16
KEGG	hsa03008	Ribosome biogenesis in eukaryotes	2/697	109/8135	0.9994	1	0.9114	WDR75/REXO2	2
KEGG	hsa04740	Olfactory transduction	4/697	440/8135	1	1	0.9114	ADCY3/OR2M4/CALML4/CNGA4	4