ONTOLOGY	ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	qvalue	geneID	Count
BP	GO:0030198	extracellular matrix organization	109/2486	368/18670	1.176e-16	7.32e-13	5.737e-13	ITGB3/COL9A2/ADAMTS2/ITGB5/MMP8/CTSG/ITGA4/HTRA1/SPARC/PLOD2/NFKB2/COL6A1/TNF/TGFB2/LAMC1/MMP1/TNXB/TGFB1/AGRN/ELANE/VWF/PXDN/GAS6/CLASP2/ITGA7/EFEMP2/COL10A1/SMPD3/TPSAB1/FN1/FOXC1/COL16A1/LAMC2/FBN2/COL18A1/SPP1/ELN/LOX/JAM2/SFRP2/SERPINH1/NPNT/KAZALD1/NID2/CCDC80/ITGA9/SMOC2/ADAMTS9/ADAMTS14/PDPN/ITGA3/ST7/COL27A1/FLRT2/COL4A1/RAMP2/LOXL1/MMP3/COL4A2/PDGFRA/PHLDB2/BGN/MMP9/ITGAL/SULF1/COL14A1/DPT/ECM2/MFAP2/MMP19/HAS2/COL5A1/CREB3L1/SOX9/NOTCH1/HAPLN1/FAP/LAMB1/VIT/HAS3/ITGB8/COL12A1/FBLN1/DCN/OLFML2A/MFAP5/HAS1/ACAN/DDR2/GFOD2/VWA1/NTN4/COL6A2/COL17A1/CLASP1/POSTN/KDR/ITGA2/FBN1/FMOD/A2M/MFAP4/PRSS2/TNC/SPINT2/FBLN2/COL5A2/MMP25/COL1A2	109
BP	GO:0043062	extracellular structure organization	119/2486	422/18670	2.802e-16	8.72e-13	6.835e-13	ITGB3/COL9A2/ADAMTS2/ITGB5/MMP8/CTSG/ITGA4/HTRA1/SPARC/ARF1/PLOD2/NFKB2/COL6A1/TNF/LPL/TGFB2/LAMC1/MMP1/TNXB/TGFB1/AGRN/ELANE/VWF/PXDN/GAS6/CLASP2/ITGA7/EFEMP2/COL10A1/SMPD3/TPSAB1/FN1/FOXC1/COL16A1/APOC1/LAMC2/FBN2/COL18A1/SPP1/ELN/LOX/JAM2/SFRP2/SERPINH1/NPNT/KAZALD1/NID2/CCDC80/ITGA9/SMOC2/ADAMTS9/ADAMTS14/PDPN/ITGA3/ST7/COL27A1/GPIHBP1/FLRT2/COL4A1/RAMP2/LOXL1/MMP3/COL4A2/PDGFRA/PHLDB2/BGN/MMP9/ITGAL/AGTR1/SULF1/COL14A1/DPT/ECM2/MFAP2/MMP19/HAS2/COL5A1/CREB3L1/SOX9/CD34/NOTCH1/HAPLN1/PLAGL2/PLA2G2A/FAP/LAMB1/VIT/HAS3/ITGB8/COL12A1/FBLN1/DCN/OLFML2A/MFAP5/HAS1/ACAN/DDR2/GFOD2/VWA1/NTN4/COL6A2/COL17A1/CLASP1/POSTN/KDR/ITGA2/FBN1/FMOD/PLTP/A2M/MFAP4/PRSS2/TNC/SPINT2/FBLN2/COL5A2/HYAL1/MMP25/COL1A2	119
BP	GO:0071560	cellular response to transforming growth factor beta stimulus	77/2486	249/18670	3.191e-13	5.328e-10	4.176e-10	LTBP1/ACVR1/HTRA4/ITGB5/PDPK1/CLDN5/HTRA1/ARG1/EP300/USP9Y/VEPH1/PARD3/HPGD/CAV2/SMAD7/JUN/CD109/TGFB2/CRKL/TGFB1/CREB1/PDE2A/UBA52/CDKN1C/TGFBRAP1/TWSG1/MIR21/FLCN/CREBBP/SMAD1/ZBTB7A/HTRA3/FOS/DAB2/FBN2/SIRT1/LOX/PML/NPNT/ACVR2A/SKIL/ITGA3/COL4A2/MIR17HG/CBL/TGFB1I1/FERMT2/PPM1A/SOX9/LTBP2/SFRP1/CDKN2B/ASPN/NR3C1/UBC/LIMS1/NOX4/WNT5A/PARD6A/CDH5/HSP90AB1/CILP/CAV1/POSTN/FBN1/PDCD5/FMOD/RASL11B/HSPA5/MTMR4/LTBP4/SOX6/DKK3/GIPC1/PIN1/CLEC3B/COL1A2	77
BP	GO:0071559	response to transforming growth factor beta	78/2486	255/18670	4.225e-13	5.328e-10	4.176e-10	LTBP1/ACVR1/HTRA4/ITGB5/PDPK1/CLDN5/HTRA1/ARG1/EP300/USP9Y/VEPH1/PARD3/HPGD/CAV2/SMAD7/JUN/CD109/TGFB2/CRKL/TGFB1/CREB1/PDE2A/UBA52/CDKN1C/TGFBRAP1/TWSG1/MIR21/FLCN/CREBBP/SMAD1/ZBTB7A/HTRA3/FOS/DAB2/FBN2/SIRT1/LOX/PML/NPNT/ACVR2A/SKIL/ITGA3/COL4A2/MIR17HG/CBL/TGFB1I1/FERMT2/PPM1A/SOX9/LTBP2/MXRA5/SFRP1/CDKN2B/ASPN/NR3C1/UBC/LIMS1/NOX4/WNT5A/PARD6A/CDH5/HSP90AB1/CILP/CAV1/POSTN/FBN1/PDCD5/FMOD/RASL11B/HSPA5/MTMR4/LTBP4/SOX6/DKK3/GIPC1/PIN1/CLEC3B/COL1A2	78
BP	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	97/2486	349/18670	4.279e-13	5.328e-10	4.176e-10	RBM14/LTBP1/ACVR1/HTRA4/ITGB5/PDPK1/CLDN5/PELO/HTRA1/RGMA/INHBA/EP300/USP9Y/VEPH1/PARD3/HPGD/CAV2/SMAD7/JUN/CD109/BTBD11/TGFB2/NUP93/FSTL1/TGFB1/SORL1/CREB1/HES1/UBA52/CDKN1C/RBPMS2/TGFBRAP1/PCSK6/TWSG1/MIR21/SMPD3/FLCN/CREBBP/SMAD1/BMP2/ZBTB7A/HTRA3/FOS/DAB2/FBN2/SIRT1/WWTR1/LOX/SFRP2/PML/NPNT/ACVR2A/SKIL/TGIF2/ITGA3/MIR17HG/CBL/INHBE/TGFB1I1/FERMT2/SULF1/SFRP4/PPM1A/GREM2/BMP8A/NOTCH1/LTBP2/DACT2/SFRP1/RBPMS/CDKN2B/ZNF423/ASPN/UBC/UBE2D3/FKBP8/WNT5A/MSX1/RYR2/MAGI2/PARD6A/CDH5/HSP90AB1/CILP/CAV1/TTK/FBN1/FMOD/RASL11B/HSPA5/MTMR4/LTBP4/DKK3/GIPC1/CHRDL1/PIN1/COL1A2	97
BP	GO:0090287	regulation of cellular response to growth factor stimulus	83/2486	292/18670	5.891e-12	6.053e-09	4.744e-09	ITGB3/GRB10/LTBP1/SPRY2/DSTYK/HTRA4/NTF3/PDPK1/PELO/HTRA1/EP300/VEPH1/PRKCB/CAV2/SMAD7/FLT1/CD109/VEGFC/FSTL1/TGFB1/SORL1/PTP4A3/SPRY1/HES1/UBA52/CDKN1C/RBPMS2/PCSK6/TWSG1/FLCN/CREBBP/FGF18/ZBTB7A/HTRA3/DAB2/FBN2/MMRN2/SIRT1/LOX/SFRP2/SPRY4/NPNT/SKIL/SMOC2/ITGA3/MIR17HG/TGFB1I1/SULF1/SFRP4/PPM1A/WASF1/GREM2/MYO1C/CREB3L1/NOTCH1/IL1B/SFRP1/CDKN2B/GPC1/ZNF423/ASPN/UBC/FKBP8/WNT5A/DCN/MSX1/CDH5/HSP90AB1/CAV1/SLIT2/FBN1/FZD4/RASL11B/HSPA5/MTMR4/DOK5/ADAMTS12/LTBP4/DKK3/GIPC1/CHRDL1/PIN1/CCBE1	83
BP	GO:0031589	cell-substrate adhesion	95/2486	354/18670	6.806e-12	6.053e-09	4.744e-09	ITGB3/TRIP6/CTTN/ITGB5/ARHGAP6/PDPK1/PTPRO/ITGA4/MYADM/OLFM4/CSF1/LIMS2/HOXA7/CRKL/LAMC1/LDB1/PLEKHA2/VWF/BCAM/NRP1/GAS6/L1CAM/CLASP2/ITGA7/CX3CL1/FN1/COL16A1/LAMC2/MMRN2/ARHGEF7/JUP/NPNT/MMRN1/NID2/CCDC80/SMOC2/CEACAM6/ADAMTS9/PDPN/ITGA3/PTN/EPDR1/UTRN/AP1AR/PHLDB2/ITGAL/SGCE/FERMT2/WHAMM/THBS3/ACTN1/ECM2/EMP2/HAS2/CD34/NOTCH1/TEK/EMILIN3/NEDD9/CCL21/SFRP1/LYVE1/SORBS1/THY1/LAMB1/ANGPT2/VIT/LIMS1/PPM1F/FBLN1/RREB1/FAM107A/FLNA/ARPC2/DDR2/ITGBL1/NTN4/COL17A1/CLASP1/DLC1/POSTN/KDR/EDIL3/ITGA2/TMEM8B/FZD4/SEMA3E/RADIL/ADAMTS12/FBLN2/CORO1A/PARVA/LIMCH1/AXL/KIF14	95
BP	GO:0034329	cell junction assembly	72/2486	241/18670	1.165e-11	8.059e-09	6.316e-09	TRIP6/CTTN/TNS1/ARHGAP6/PDPK1/CLDN5/PTPRO/MPP5/APC/PARD3/RAB13/CD9/TNF/PARD6G/SMAD7/LIMS2/DLG1/ESAM/FBLIM1/LAMC1/LDB1/HIPK1/NRP1/ACE/CLASP2/GJA5/FLCN/FN1/COL16A1/LAMC2/GJA4/ARHGEF7/JUP/CDH26/RAMP2/NPHP1/PHLDB2/FERMT2/WHAMM/ACTN1/PKP4/MYO1C/CAPZA1/FLNC/TEK/SFRP1/SORBS1/THY1/MPP7/FZD5/ANK2/LIMS1/PKN2/PPM1F/FAM107A/FLNA/TJP1/PARD6A/CDH5/CAV1/COL17A1/CLASP1/DLC1/KDR/ITGA2/CDH6/NR1H4/LIMCH1/PARD6B/CDH11/CD151/KRT5	72
BP	GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	72/2486	241/18670	1.165e-11	8.059e-09	6.316e-09	LTBP1/ACVR1/HTRA4/PDPK1/PELO/HTRA1/INHBA/EP300/VEPH1/CAV2/SMAD7/CD109/TGFB2/NUP93/FSTL1/TGFB1/SORL1/HES1/UBA52/CDKN1C/RBPMS2/PCSK6/TWSG1/FLCN/CREBBP/BMP2/ZBTB7A/HTRA3/DAB2/FBN2/SIRT1/WWTR1/LOX/SFRP2/NPNT/ACVR2A/SKIL/ITGA3/MIR17HG/INHBE/TGFB1I1/SULF1/SFRP4/PPM1A/GREM2/BMP8A/NOTCH1/DACT2/SFRP1/RBPMS/CDKN2B/ZNF423/ASPN/UBC/FKBP8/WNT5A/MSX1/MAGI2/CDH5/HSP90AB1/CILP/CAV1/TTK/FBN1/RASL11B/HSPA5/MTMR4/LTBP4/DKK3/GIPC1/CHRDL1/PIN1	72
BP	GO:0007179	transforming growth factor beta receptor signaling pathway	62/2486	199/18670	4.495e-11	2.798e-08	2.193e-08	LTBP1/ACVR1/HTRA4/ITGB5/PDPK1/CLDN5/HTRA1/EP300/USP9Y/VEPH1/PARD3/HPGD/CAV2/SMAD7/JUN/CD109/TGFB2/TGFB1/CREB1/UBA52/CDKN1C/TGFBRAP1/TWSG1/MIR21/FLCN/CREBBP/SMAD1/ZBTB7A/HTRA3/FOS/DAB2/FBN2/SIRT1/LOX/PML/NPNT/ACVR2A/SKIL/ITGA3/MIR17HG/CBL/TGFB1I1/FERMT2/PPM1A/LTBP2/CDKN2B/ASPN/UBC/PARD6A/CDH5/HSP90AB1/CAV1/FBN1/FMOD/RASL11B/HSPA5/MTMR4/LTBP4/DKK3/GIPC1/PIN1/COL1A2	62
BP	GO:0034330	cell junction organization	79/2486	290/18670	1.842e-10	1.043e-07	8.172e-08	TRIP6/CTTN/TNS1/ARHGAP6/PDPK1/CLDN5/CD177/PTPRO/MPP5/APC/PARD3/RAB13/CD9/TNF/PARD6G/SMAD7/LIMS2/DLG1/ESAM/TGFB2/FBLIM1/LAMC1/TGFB1/LDB1/HIPK1/NRP1/ACE/PLEKHA7/CLASP2/GJA5/FLCN/FN1/COL16A1/LAMC2/GJA4/ARHGEF7/JUP/CDH26/RAMP2/NPHP1/PHLDB2/SDK1/FERMT2/WHAMM/ACTN1/PKP4/MYO1C/CAPZA1/FLNC/TEK/SFRP1/SORBS1/THY1/MPP7/CADM3/FZD5/ANK2/LIMS1/PKN2/PPM1F/FAM107A/FLNA/TJP1/PARD6A/CDH5/CAV1/NLGN4X/COL17A1/CLASP1/DLC1/KDR/ITGA2/CDH6/NR1H4/LIMCH1/PARD6B/CDH11/CD151/KRT5	79
BP	GO:0048705	skeletal system morphogenesis	66/2486	239/18670	3.122e-09	1.619e-06	1.269e-06	LRP5L/COCH/HOXB5/MEF2D/COL6A1/NIPBL/TMEM119/TWIST1/DLG1/HOXA7/LTF/TGFB1/TIPARP/CYP26B1/SMPD3/FOXC1/FGF18/ALPL/SCARA3/WDR19/FBN2/SFRP2/STC1/P2RX7/SERPINH1/FOXN3/SATB2/COL27A1/SIX1/HOXB7/PDGFRA/HOXD8/CSRNP1/WNT9A/COL14A1/SFRP4/THBS3/PRRX1/HAS2/IFT140/SOX9/SHOX2/ACP5/GLI3/HOXA11/MATN2/TEK/HOXC9/SFRP1/TBX15/VIT/COL12A1/COL21A1/MSX1/ACAN/TBX1/PCGF2/SIX2/VWA1/COL6A2/MGP/HOXA3/LRP5/SETD2/HYAL1/HOXD9	66
BP	GO:0072001	renal system development	75/2486	293/18670	1.046e-08	5.008e-06	3.925e-06	MME/ARG2/PTPRO/FADD/IRX2/HEYL/NIPBL/PBX1/HPGD/SMAD7/DLG1/TGFB2/NUP93/TGFB1/SPRY1/KANK2/HES1/CDKN1C/NRP1/CRLF1/ACE/TIPARP/CYP26B1/FLCN/SMAD1/FOXC1/BMP2/IRX3/GPR4/WWTR1/NPNT/MTSS1/ITGA3/ASS1/SIX1/COL4A1/HOXB7/JMJD6/PDGFRA/NUP160/MMP9/AGTR1/SULF1/EFNB2/SMO/GLIS2/PDGFRB/HAS2/IFT140/SOX9/CD34/NOTCH1/YAP1/GLI3/HOXA11/TEK/DACT2/SFRP1/ALDH1A2/ANGPT2/WNT5A/ADAMTS16/DCN/MAGI2/EMX2/PODXL/SIX2/SLIT2/GZF1/FBN1/ACTA2/WFS1/ENPEP/NOTCH3/LZTS2	75
BP	GO:0051098	regulation of binding	89/2486	373/18670	1.821e-08	8.099e-06	6.348e-06	SIRT2/SRI/SLPI/HJURP/MMP8/GAS8/PPARG/ITGA4/EP300/GATA1/BDNF/NFKBIA/TRIM6/NIPBL/TAF10/TWIST1/JUN/PPP2CA/SPPL3/TDG/DHX9/TGFB1/CDK9/SORL1/TRAF4/IFI16/HES1/NRP1/ACE/EIF2S1/FBXW7/ZNF462/PARP9/IRF4/FOXC1/BMP2/ZBTB7A/CRMP1/NFATC4/DAB2/ARHGEF7/DDX11/DDIT3/TRAF6/LOX/CYLD/DERL1/CFHR2/IGF1/EGF/CSNK1A1/MFNG/PTPRF/MMP9/MAP2/STK4/RSF1/TTBK2/ARHGAP28/IFIT1/CDON/SMO/POU4F1/KLF4/PLK1/GREM2/NSD1/DTX3L/CTHRC1/NES/WNT5A/USP33/DZIP1/MSX1/HSP90AB1/EBF2/CAV1/BTAF1/BAK1/ITGA2/TAF1/GPSM1/SPON1/HSPA5/HOXA3/SIN3A/NEK2/PIN1/LARP6	89
BP	GO:0001655	urogenital system development	81/2486	330/18670	2.104e-08	8.731e-06	6.843e-06	MME/ARG2/PTPRO/FADD/IRX2/HEYL/NIPBL/PBX1/HPGD/SMAD7/DLG1/TGFB2/NUP93/CRKL/TGFB1/FKBP4/SPRY1/KANK2/HES1/CDKN1C/NRP1/CRLF1/ACE/TIPARP/CYP26B1/FLCN/SMAD1/SMARCC1/FOXC1/BMP2/IRX3/GPR4/WWTR1/NPNT/MTSS1/ITGA3/ASS1/SIX1/COL4A1/HOXB7/JMJD6/PDGFRA/NUP160/MMP9/AGTR1/SULF1/EFNB2/SMO/GLIS2/FRS2/PDGFRB/HAS2/IFT140/SOX9/CD34/NOTCH1/YAP1/GLI3/HOXA11/TEK/DACT2/SFRP1/ALDH1A2/ANGPT2/WNT5A/ADAMTS16/DCN/MAGI2/EMX2/PODXL/SIX2/SLIT2/GZF1/FBN1/ACTA2/WFS1/ENPEP/TNC/EPHB2/NOTCH3/LZTS2	81
BP	GO:0048880	sensory system development	88/2486	371/18670	2.934e-08	1.141e-05	8.946e-06	C1QA/LRP5L/ARID1A/MAF/TMOD1/YY1/INHBA/NIPBL/RAB11FIP4/TUB/TWIST1/JUN/DLG1/TGFB2/B9D1/WNT5B/TGFB1/PHACTR4/HIPK1/CDKN1C/NRP1/TWSG1/HSF4/P2RY12/THRB/FOXC1/CLN8/WDR19/FBN2/MAX/SP3/MDM1/EGFR/NTRK2/MEIS2/SKIL/TGIF2/PTN/AGTPBP1/COL4A1/JMJD6/RHOJ/PDGFRA/NPHP1/WNT9A/BCAR3/ROM1/SDK1/SIX5/CDON/FAT1/POU4F1/BFSP1/FRS2/KLF4/MFAP2/PDGFRB/IFT140/COL5A1/SOX9/TBX2/NDP/SMOC1/TSKU/PRPH2/ALDH1A3/GLI3/ALDH1A2/THY1/NES/FZD5/FKBP8/MAB21L2/WNT5A/EFEMP1/MAN2A1/BAK1/TMEM231/MYH10/FBN1/FZD4/CRYAB/EPHB2/ARHGEF15/COL5A2/LRP5/CHRDL1/LPCAT1	88
BP	GO:0150063	visual system development	87/2486	366/18670	3.163e-08	1.158e-05	9.077e-06	C1QA/LRP5L/ARID1A/MAF/TMOD1/YY1/INHBA/NIPBL/RAB11FIP4/TUB/TWIST1/JUN/DLG1/TGFB2/B9D1/WNT5B/TGFB1/PHACTR4/HIPK1/CDKN1C/NRP1/TWSG1/HSF4/P2RY12/THRB/FOXC1/CLN8/WDR19/FBN2/MAX/SP3/MDM1/EGFR/NTRK2/MEIS2/SKIL/TGIF2/PTN/AGTPBP1/COL4A1/JMJD6/RHOJ/PDGFRA/NPHP1/WNT9A/BCAR3/ROM1/SDK1/SIX5/CDON/FAT1/BFSP1/FRS2/KLF4/MFAP2/PDGFRB/IFT140/COL5A1/SOX9/TBX2/NDP/SMOC1/TSKU/PRPH2/ALDH1A3/GLI3/ALDH1A2/THY1/NES/FZD5/FKBP8/MAB21L2/WNT5A/EFEMP1/MAN2A1/BAK1/TMEM231/MYH10/FBN1/FZD4/CRYAB/EPHB2/ARHGEF15/COL5A2/LRP5/CHRDL1/LPCAT1	87
BP	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	39/2486	120/18670	4.806e-08	1.585e-05	1.242e-05	LTBP1/HTRA4/PDPK1/HTRA1/EP300/VEPH1/CAV2/SMAD7/CD109/TGFB1/UBA52/CDKN1C/FLCN/CREBBP/ZBTB7A/HTRA3/DAB2/FBN2/SIRT1/LOX/NPNT/SKIL/ITGA3/MIR17HG/TGFB1I1/PPM1A/CDKN2B/ASPN/UBC/HSP90AB1/CAV1/FBN1/RASL11B/HSPA5/MTMR4/LTBP4/DKK3/GIPC1/PIN1	39
BP	GO:0043010	camera-type eye development	77/2486	314/18670	4.868e-08	1.585e-05	1.242e-05	LRP5L/ARID1A/MAF/TMOD1/YY1/INHBA/RAB11FIP4/TUB/TWIST1/JUN/DLG1/TGFB2/B9D1/WNT5B/TGFB1/PHACTR4/HIPK1/CDKN1C/NRP1/TWSG1/HSF4/THRB/FOXC1/CLN8/WDR19/FBN2/MAX/SP3/MDM1/EGFR/NTRK2/SKIL/TGIF2/PTN/COL4A1/JMJD6/RHOJ/PDGFRA/NPHP1/WNT9A/BCAR3/ROM1/SDK1/SIX5/CDON/FAT1/BFSP1/FRS2/KLF4/PDGFRB/IFT140/SOX9/TBX2/NDP/TSKU/PRPH2/ALDH1A3/GLI3/ALDH1A2/THY1/NES/FZD5/FKBP8/MAB21L2/WNT5A/EFEMP1/MAN2A1/BAK1/TMEM231/MYH10/FBN1/FZD4/CRYAB/EPHB2/ARHGEF15/LRP5/LPCAT1	77
BP	GO:0006413	translational initiation	54/2486	193/18670	5.093e-08	1.585e-05	1.242e-05	RPS27/RPS28/RBM4/EIF5/PPP1R15A/PPP1R15B/PAIP2B/EIF3L/EIF1AY/EIF4B/EIF2AK4/TNF/YTHDF2/RPS15/UBA52/DENR/EIF2S1/RPS26/LARP1/RPLP1/RPL28/RPS3A/EIF1/PAIP2/RPL10/YTHDF1/EIF2A/HSPB1/EIF4H/EIF3F/RPL29/POLR2G/RPS8/RPS4Y1/RPS2/RPL39/RPS10/RPL6/KHDRBS1/MIF4GD/YTHDF3/EIF3K/EIF3M/RPL14/RPS7/MTOR/CDC123/UHMK1/POLR2D/EIF4A1/ABCE1/RPL9/EIF2B2/RPL15	54
BP	GO:0010811	positive regulation of cell-substrate adhesion	39/2486	121/18670	6.189e-08	1.833e-05	1.436e-05	MYADM/OLFM4/CSF1/LIMS2/CRKL/PLEKHA2/NRP1/CX3CL1/FN1/COL16A1/MMRN2/ARHGEF7/JUP/NPNT/MMRN1/CCDC80/SMOC2/CEACAM6/ITGA3/PTN/UTRN/ECM2/EMP2/HAS2/TEK/EMILIN3/NEDD9/CCL21/SFRP1/THY1/VIT/LIMS1/PPM1F/RREB1/FLNA/ARPC2/KDR/EDIL3/FBLN2	39
BP	GO:0001822	kidney development	70/2486	278/18670	6.477e-08	1.833e-05	1.436e-05	MME/ARG2/PTPRO/FADD/IRX2/HEYL/NIPBL/PBX1/HPGD/SMAD7/DLG1/TGFB2/TGFB1/SPRY1/KANK2/HES1/CDKN1C/NRP1/CRLF1/ACE/TIPARP/CYP26B1/FLCN/SMAD1/FOXC1/BMP2/IRX3/GPR4/WWTR1/NPNT/MTSS1/ITGA3/ASS1/SIX1/HOXB7/JMJD6/PDGFRA/NUP160/MMP9/AGTR1/SULF1/EFNB2/SMO/GLIS2/PDGFRB/HAS2/SOX9/CD34/NOTCH1/YAP1/GLI3/HOXA11/TEK/DACT2/SFRP1/ALDH1A2/ANGPT2/ADAMTS16/DCN/MAGI2/PODXL/SIX2/SLIT2/GZF1/FBN1/ACTA2/WFS1/ENPEP/NOTCH3/LZTS2	70
BP	GO:0010810	regulation of cell-substrate adhesion	58/2486	215/18670	6.789e-08	1.837e-05	1.44e-05	ARHGAP6/PTPRO/MYADM/OLFM4/CSF1/LIMS2/HOXA7/CRKL/LDB1/PLEKHA2/NRP1/CLASP2/CX3CL1/FN1/COL16A1/MMRN2/ARHGEF7/JUP/NPNT/MMRN1/CCDC80/SMOC2/CEACAM6/PDPN/ITGA3/PTN/UTRN/AP1AR/PHLDB2/ECM2/EMP2/HAS2/NOTCH1/TEK/EMILIN3/NEDD9/CCL21/SFRP1/THY1/ANGPT2/VIT/LIMS1/PPM1F/FBLN1/RREB1/FAM107A/FLNA/ARPC2/DDR2/CLASP1/DLC1/POSTN/KDR/EDIL3/FZD4/SEMA3E/FBLN2/LIMCH1	58
BP	GO:1903844	regulation of cellular response to transforming growth factor beta stimulus	39/2486	122/18670	7.939e-08	2.023e-05	1.586e-05	LTBP1/HTRA4/PDPK1/HTRA1/EP300/VEPH1/CAV2/SMAD7/CD109/TGFB1/UBA52/CDKN1C/FLCN/CREBBP/ZBTB7A/HTRA3/DAB2/FBN2/SIRT1/LOX/NPNT/SKIL/ITGA3/MIR17HG/TGFB1I1/PPM1A/CDKN2B/ASPN/UBC/HSP90AB1/CAV1/FBN1/RASL11B/HSPA5/MTMR4/LTBP4/DKK3/GIPC1/PIN1	39
BP	GO:0001654	eye development	85/2486	362/18670	8.126e-08	2.023e-05	1.586e-05	LRP5L/ARID1A/MAF/TMOD1/YY1/INHBA/NIPBL/RAB11FIP4/TUB/TWIST1/JUN/DLG1/TGFB2/B9D1/WNT5B/TGFB1/PHACTR4/HIPK1/CDKN1C/NRP1/TWSG1/HSF4/THRB/FOXC1/CLN8/WDR19/FBN2/MAX/SP3/MDM1/EGFR/NTRK2/MEIS2/SKIL/TGIF2/PTN/AGTPBP1/COL4A1/JMJD6/RHOJ/PDGFRA/NPHP1/WNT9A/BCAR3/ROM1/SDK1/SIX5/CDON/FAT1/BFSP1/FRS2/KLF4/MFAP2/PDGFRB/IFT140/COL5A1/SOX9/TBX2/NDP/SMOC1/TSKU/PRPH2/ALDH1A3/GLI3/ALDH1A2/THY1/NES/FZD5/FKBP8/MAB21L2/WNT5A/EFEMP1/MAN2A1/BAK1/TMEM231/MYH10/FBN1/FZD4/CRYAB/EPHB2/ARHGEF15/COL5A2/LRP5/CHRDL1/LPCAT1	85
BP	GO:0060348	bone development	58/2486	217/18670	9.632e-08	2.258e-05	1.77e-05	LRP5L/COCH/SH2B3/MEF2D/SPARC/EP300/COL6A1/WASF2/TMEM119/TWIST1/LTF/GHRL/TGFB1/TAL1/AKAP13/FBXW7/CYP26B1/SMPD3/SMAD1/FOXC1/FGF18/BMP2/ALPL/SCARA3/PTGER4/PHEX/BBX/LOX/SFRP2/STC1/SEMA4D/SERPINH1/IGF1/FOXN3/COL27A1/FLI1/SULF1/COL14A1/SFRP4/THBS3/HAS2/SOX9/SHOX2/ACP5/NOTCH2/GLI3/HOXA11/MATN2/TEK/VIT/COL12A1/COL21A1/MSX1/VWA1/COL6A2/FBN1/PTPRC/LRP5	58
BP	GO:0045785	positive regulation of cell adhesion	92/2486	403/18670	9.794e-08	2.258e-05	1.77e-05	FAM49B/PDPK1/HLA-DPB1/FADD/BAG4/ITGA4/MYADM/OLFM4/CSF1/TNF/SMAD7/LIMS2/DUSP10/BCL10/TGFB2/CRKL/TGFB1/TPM1/IGFBP2/LDB1/ELANE/PLEKHA2/CD276/HES1/NRP1/CX3CL1/CD83/MIR21/FLCN/P2RY12/FN1/NFKBIZ/COL16A1/HLX/MMRN2/ARHGEF7/TRAF6/JUP/IL23R/CYLD/VAV1/SFRP2/NPNT/MMRN1/CCDC80/SMOC2/CEACAM6/IGF1/RELA/CXCL12/PDPN/ITGA3/PTN/UTRN/PDCD1LG2/IL12A/EFNB2/IL2/ECM2/EMP2/HAS2/TNFRSF14/GLI3/IL1B/TEK/STX4/EMILIN3/NEDD9/CCL21/SFRP1/THY1/VIT/LIMS1/PPM1F/VAV3/RREB1/WNT5A/PAK3/FLNA/PODXL/ARPC2/CAV1/LYN/KDR/EDIL3/ITGA2/PRSS2/PTPRC/FBLN2/CORO1A/DOCK8/HYAL1	92
BP	GO:0001667	ameboidal-type cell migration	102/2486	461/18670	1.048e-07	2.269e-05	1.779e-05	ITGB3/ANXA3/TNS1/ACVR1/PDPK1/EDNRB/PPARG/BAG4/ITGA4/SEMA3B/SPARC/C5orf30/WASF2/RAB13/TWIST1/JUN/DUSP10/TGFB2/VEGFC/TGFB1/PTP4A3/SEMA3G/ANLN/KANK2/PHACTR4/CYGB/NRP1/CLASP2/FBXW7/MIR21/P2RY12/ZC3H12A/FN1/FGF18/CAPN7/MMRN2/ARHGEF7/EDN3/SIRT1/JUP/PDXDC1/NOS3/HSPB1/STC1/SEMA4D/PML/SMOC2/ADAMTS9/ITGA3/PLEKHG5/CARD10/SEMA6D/SEMA5B/VASH1/PTN/EPHB4/RHOJ/CEACAM1/MMP9/NR2F2/DNAJA4/SRPX2/TMEM201/EFNB2/SMO/MEOX2/BCAR1/KLF4/AMOTL2/EMP2/HAS2/SOX9/NOTCH1/CLEC14A/MYH9/TEK/PTPRG/FAP/ANGPT2/PKN3/ENPP2/PDCD10/PKN2/PPM1F/RREB1/WNT5A/PAK3/DCN/HAS1/DDR2/TBX1/MAP3K3/SLIT2/MTOR/CLASP1/KDR/ITGA2/SEMA3E/PFN1/GIPC1/HYAL1/CCBE1	102
BP	GO:0001503	ossification	91/2486	398/18670	1.065e-07	2.269e-05	1.779e-05	LRP5L/ACVR1/JUND/MEF2D/SPARC/GATA1/COL6A1/BCOR/CSF1/NIPBL/PBX1/TMEM119/TNF/TWIST1/LTF/TGFB2/DHX9/TGFB1/RPS15/TWSG1/MIR21/SMPD3/SMAD1/FOXC1/FGF18/BMP2/ALPL/DDX21/RSL1D1/MRC2/FBN2/PTGER4/SPP1/PHEX/SP3/TRAF6/WWTR1/TWIST2/EGFR/ECM1/LOX/SFRP2/STC1/SEMA4D/P2RX7/NPNT/ACVR2A/KAZALD1/IGF1/SATB2/PTN/PTH1R/TNFRSF11A/KLF10/IGFBP5/THBS3/SMO/CREB3L1/SOX9/BMP8A/SMOC1/NOTCH1/SHOX2/ACP5/IGSF10/GLI3/ANKH/CTHRC1/TEK/SFRP1/ASPN/GPNMB/REST/RBMX/WNT5A/DDR2/PKDCC/SIX2/INTU/KL/MGP/TNC/JUNB/COL5A2/LRP5/CHRDL1/CDH11/IGFBP3/CLEC3B/COL1A2/RASSF2	91
BP	GO:0060349	bone morphogenesis	37/2486	114/18670	1.094e-07	2.269e-05	1.779e-05	LRP5L/COCH/MEF2D/COL6A1/TMEM119/TWIST1/LTF/TGFB1/CYP26B1/SMPD3/FOXC1/FGF18/ALPL/SCARA3/SFRP2/STC1/SERPINH1/FOXN3/COL27A1/COL14A1/SFRP4/THBS3/HAS2/SOX9/SHOX2/ACP5/GLI3/HOXA11/MATN2/TEK/VIT/COL12A1/COL21A1/MSX1/VWA1/COL6A2/LRP5	37
BP	GO:0097193	intrinsic apoptotic signaling pathway	71/2486	289/18670	1.482e-07	2.977e-05	2.333e-05	CLU/MUC1/PMAIP1/BCLAF1/MSH6/SLC9A3R1/PPP1R15A/POLB/ITPR1/CASP4/EP300/RPS27L/TNF/NOL3/DNAJA1/SFPQ/PINK1/HYOU1/MOAP1/HIPK1/IFI16/HERPUD1/PHLDA3/FBXW7/ERN1/ERP29/STK24/MIR21/FLCN/BDKRB2/USP28/DNAJC10/NFATC4/RNF183/SIRT1/DDIT3/BCL2L1/NME5/CYLD/HSPB1/SFRP2/PML/SKIL/MAP3K5/CXCL12/DAPK2/SERINC3/HNRNPK/MMP9/BMF/MELK/POU4F1/MCL1/CREB3L1/NUPR1/IFI6/DIABLO/PLAGL2/PDCD10/PPM1F/NONO/MSX1/TP53BP2/CAV1/RPS7/TRIAP1/BAK1/WFS1/STYXL1/CUL1/CIDEB	71
BP	GO:0007160	cell-matrix adhesion	59/2486	225/18670	1.544e-07	3.004e-05	2.355e-05	ITGB3/TRIP6/CTTN/ITGB5/ARHGAP6/PDPK1/ITGA4/CSF1/HOXA7/LDB1/PLEKHA2/BCAM/NRP1/L1CAM/CLASP2/ITGA7/CX3CL1/FN1/COL16A1/ARHGEF7/JUP/NPNT/NID2/CEACAM6/ADAMTS9/ITGA3/EPDR1/UTRN/PHLDB2/ITGAL/SGCE/FERMT2/WHAMM/THBS3/ACTN1/ECM2/EMP2/CD34/TEK/CCL21/SFRP1/LYVE1/SORBS1/THY1/LIMS1/PPM1F/FAM107A/DDR2/ITGBL1/COL17A1/CLASP1/DLC1/POSTN/KDR/ITGA2/TMEM8B/SEMA3E/ADAMTS12/LIMCH1	59
BP	GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	39/2486	126/18670	2.071e-07	3.907e-05	3.062e-05	LTBP1/ACVR1/HTRA4/PDPK1/HTRA1/VEPH1/CAV2/SMAD7/CD109/TGFB1/SORL1/UBA52/RBPMS2/TWSG1/ZBTB7A/HTRA3/FBN2/SIRT1/SFRP2/SKIL/MIR17HG/TGFB1I1/PPM1A/GREM2/NOTCH1/DACT2/SFRP1/ASPN/UBC/WNT5A/MAGI2/CILP/CAV1/FBN1/RASL11B/HSPA5/MTMR4/CHRDL1/PIN1	39
BP	GO:0010498	proteasomal protein catabolic process	103/2486	477/18670	3.174e-07	5.812e-05	4.555e-05	CLU/SIRT2/ENC1/IFI27/PSMD14/PMAIP1/PSMD12/GABARAPL2/SPSB1/ARAF/FBXO33/SEC61B/NUDT15/KEAP1/EDEM1/SDF2L1/HSP90B1/SMAD7/KLHL15/PSMD7/PINK1/PSMB5/KLHL20/ARIH2/HERPUD1/UBA52/RMND5A/ITCH/FBXO38/FBXW7/ERLIN1/UBXN1/SMARCC1/FBXO4/DNAJB14/DNAJC10/USP7/DAB2/SIRT1/DDIT3/WWTR1/UBE2S/ECSCR/DERL1/HECW2/ERLIN2/UCHL1/PML/CBFA2T3/UBE4B/RHBDF1/ZFAND2A/MTA1/VCP/BUB1B/WAC/CSNK1A1/RCHY1/ANAPC10/ATE1/FBXL13/FBXL8/RNF216/PLK3/TRIM2/PSMB7/PLK1/MTM1/NUPR1/STT3B/SPSB3/UBE2C/CAMLG/PSMD1/IL33/TREM2/PSMD9/SKP2/UBC/UBE2D3/FBXL14/UBE2G2/RNF139/RNF19B/CHFR/RNF103/ARIH1/TMUB2/HSP90AB1/CAV1/AUP1/TNFAIP1/TAF1/TMEM67/PSME1/PCBP2/WFS1/HSPA5/SDF2/GIPC1/KIF14/CUL1/SPSB2	103
BP	GO:0061448	connective tissue development	67/2486	273/18670	3.428e-07	6.096e-05	4.778e-05	LRP5L/CHI3L1/COCH/MAF/MEF2D/COL6A1/CSF1/EVC/SNX19/GHRL/WNT5B/TGFB1/SORL1/MIR21/SMPD3/SMAD1/FGF18/BMP2/SCARA3/NFIB/GPR4/SIRT1/ECM1/LOX/SFRP2/STC1/SERPINH1/RELA/SATB2/COL27A1/PTH1R/WNT9A/SULF1/COL14A1/THBS3/PRRX1/PDGFRB/COL5A1/SOX9/BMP8A/CD34/NOTCH1/SHOX2/GLI3/HOXA11/MATN2/VIT/ITGB8/COL12A1/COL21A1/WNT5A/EFEMP1/MSX1/ACAN/PKDCC/EBF2/SIX2/VWA1/COL6A2/ACTA2/MGP/ADAMTS12/SOX6/NR1H4/HOXA3/LRP5/HYAL1	67
BP	GO:0048568	embryonic organ development	94/2486	428/18670	4.675e-07	8.084e-05	6.336e-05	TRA2B/SPRY2/ARID1A/ACVR1/SH2B3/SLC9A3R1/HOXB5/GATA1/SYF2/NIPBL/PBX1/TNF/TWIST1/FOXI1/DLG1/HOXA7/TGFB2/SCT/ZFAT/TGFB1/TAL1/PHACTR4/HIPK1/HES1/CDKN1C/RBPMS2/GJA5/FOXC1/HLX/RPL10/WDR19/POLE/FBN2/SP3/EGFR/RARRES2/SOBP/VASH1/SATB2/SIX1/HOXB7/PDGFRA/GJB6/STK4/WNT9A/NR2F2/SEC24B/SMO/PRRX1/RSPO3/FRS2/MFAP2/IFT140/SOX9/TBX2/NOTCH1/SHOX2/YAP1/ALDH1A3/GLI3/HOXA11/CTHRC1/HOXC9/C2CD3/ALDH1A2/ZFPM2/NES/TBX15/FZD5/BPTF/WNT5A/EFEMP1/TBC1D23/MSX1/LRIG3/RYR2/TBX1/PKDCC/PCGF2/SIX2/KDR/PALB2/FBN1/E2F8/SPINT2/JUNB/EPHB2/HOXA3/COL5A2/SETD2/HYAL1/HOXD9/NCOA1/MYO15A	94
BP	GO:0032970	regulation of actin filament-based process	87/2486	388/18670	4.925e-07	8.286e-05	6.495e-05	SRI/RHOBTB1/CTTN/ARHGAP18/EPS8/NTF3/CIT/FGF13/ARHGAP6/TMOD1/BAG4/MYADM/ARF1/WASF2/DLG1/TGFB1/TPM1/RND2/AKAP13/NRP1/RHOF/CLASP2/ASAP3/GJA5/CX3CL1/MIR21/PAM/PDE4B/RAPGEF3/PTGER4/ELN/JUP/AVIL/STC1/CXCL12/PDPN/COTL1/RND3/AP1AR/RHOJ/PDGFRA/PHLDB2/FZD10/PFN4/LMOD1/ARHGAP28/RND1/PLEKHH2/WHAMM/WASF1/PDGFRB/MYO1C/CAPZA1/NOTCH2/TMSB4Y/MYH9/TEK/FCHSD2/CCL21/SFRP1/CDK5R1/ANK2/NCKAP1/TMSB15A/NOX4/PPM1F/PAK3/MIR214/FAM107A/FLNA/RYR2/ARPC2/CAV1/SLIT2/HCLS1/MTOR/CLASP1/DLC1/SEMA3E/KANK3/PFN1/CDC42EP5/CORO1A/ARHGEF15/LIMCH1/MAGEL2/SHANK3	87
BP	GO:0007044	cell-substrate junction assembly	32/2486	97/18670	5.121e-07	8.389e-05	6.575e-05	TRIP6/CTTN/TNS1/ARHGAP6/PDPK1/LAMC1/LDB1/NRP1/CLASP2/FN1/COL16A1/LAMC2/ARHGEF7/PHLDB2/FERMT2/WHAMM/ACTN1/TEK/SFRP1/SORBS1/THY1/LIMS1/PPM1F/FAM107A/COL17A1/CLASP1/DLC1/KDR/ITGA2/LIMCH1/CD151/KRT5	32
BP	GO:0030323	respiratory tube development	48/2486	176/18670	6.294e-07	0.0001005	7.874e-05	SPRY2/CHI3L1/ADAMTS2/SIM2/MME/SPARC/ARG1/EP300/LIPA/TBX5/TNF/CREB1/SPRY1/TRAF4/HES1/FBXW7/SMPD3/THRB/FGF18/NFIB/PHEX/SP3/HECA/EGFR/LOX/NOS3/PDPN/ITGA3/HSD11B1/PTN/JMJD6/PDGFRA/MIR17HG/IGFBP5/SEC24B/PDGFRB/SOX9/NOTCH1/YAP1/GLI3/ALDH1A2/ZFPM2/SLC23A1/WNT5A/PKDCC/MAN2A1/TNC/CCBE1	48
BP	GO:0002062	chondrocyte differentiation	37/2486	123/18670	9.214e-07	0.000141	0.0001105	COCH/MAF/MEF2D/COL6A1/SNX19/WNT5B/TGFB1/SMPD3/FGF18/BMP2/SCARA3/NFIB/ECM1/SFRP2/SERPINH1/RELA/COL27A1/PTH1R/WNT9A/SULF1/COL14A1/SOX9/SHOX2/GLI3/HOXA11/MATN2/VIT/COL12A1/COL21A1/EFEMP1/ACAN/PKDCC/SIX2/VWA1/COL6A2/ADAMTS12/SOX6	37
BP	GO:0070482	response to oxygen levels	87/2486	394/18670	9.766e-07	0.000141	0.0001105	SIRT2/ALAS2/PSMD14/PMAIP1/PSMD12/SCFD1/DDAH1/POLB/ITPR1/PPARG/EP300/PLOD2/HSP90B1/TWIST1/NOL3/TGFB2/VEGFC/TGFB1/PSMD7/PINK1/PSMB5/PHB2/TRH/HYOU1/CREB1/CYGB/UBA52/CACNB3/ATP6V0A2/MIR21/CREBBP/RAF1/PAM/BMP2/ANGPTL4/SIRT1/MDM4/SLC2A8/HSD11B2/STC1/PML/TBL2/CBFA2T3/CXCL12/CHCHD2/PTN/RAMP2/CBL/KCNA5/PLAT/FUNDC1/KCNMA1/PLK3/AQP1/PSMB7/CPEB1/KCNK3/PDGFRB/TMEM199/CD34/NOTCH1/POLG/TEK/PSMD1/SFRP1/ANGPT2/PSMD9/UBC/OXTR/REST/NOX4/MIR214/APOLD1/NR4A2/RYR2/CAV1/STC2/MTOR/POSTN/ITGA2/SOD3/PSME1/CRYAB/MTHFR/PIN1/ABAT/CPEB2	87
BP	GO:2000027	regulation of animal organ morphogenesis	62/2486	253/18670	9.772e-07	0.000141	0.0001105	PSMD14/PSMD12/ACVR1/TNFAIP3/BCOR/CSF1/TBX5/TNF/TWIST1/LIMS2/PLEKHA4/TGFB2/TGFB1/PSMD7/PSMB5/PHB2/SPRY1/HES1/FBXW7/THRB/FOXC1/BMP2/GPC4/NFIB/DAB2/AP2A2/SFRP2/DMRT3/PTN/SIX1/HOXB7/GPC6/CEACAM1/SULF1/SEC24B/SMO/RSPO3/PSMB7/FRS2/SOX9/TBX2/CD34/NOTCH1/HOXA11/CTHRC1/PSMD1/SFRP1/PSMD9/FZD5/ASPN/WNT5A/MSX1/ROR1/MAGI2/PARD6A/TBX1/SIX2/NTN4/FZD4/PSME1/PFN1/PRICKLE2	62
BP	GO:0001933	negative regulation of protein phosphorylation	93/2486	429/18670	9.817e-07	0.000141	0.0001105	SIRT2/SPRY2/SH2B3/NTF3/SLC9A3R1/PDPK1/PPP1R15B/SH3BP5L/TNFAIP3/MYADM/PTPN13/APC/PARD3/PRKAR2A/SNCA/TWIST1/SMAD7/JUN/CD109/DLG1/DUSP10/PPP2CA/DNAJA1/CRKL/TGFB1/PINK1/SORL1/SPRY1/CDKN1C/PRDM15/ITCH/TNIP1/ADARB1/IPO7/PPEF2/CTDSPL/CDKN2C/MIR21/FLCN/ZC3H12A/IGF1R/BDKRB2/ITPRIP/CHMP6/DNAJC10/SIRT1/WWTR1/CYLD/SMCR8/HSPB1/SFRP2/SEMA4D/P2RX7/SPRY4/UCHL1/PKIB/CBL/CEACAM1/TIMP3/NR2F2/IL2/KLF4/PLK1/PRKAG2/IL1B/IBTK/SFRP1/THY1/CDKN2B/FKBP8/PPM1F/FBLN1/IPO5/PARD6A/DUSP1/CD300A/CAV1/SLIT2/INPP5F/MTOR/LYN/DUSP18/BAK1/RGS14/DMD/PRKAR2B/PER1/EPHB2/PTPRC/LRP5/IGFBP3/PIN1/RASSF2	93
BP	GO:0007015	actin filament organization	88/2486	400/18670	9.985e-07	0.000141	0.0001105	RHOBTB1/CTTN/ARHGAP18/EPS8/TTC17/CIT/AIF1L/ITGB5/ARHGAP6/TMOD1/BAG4/MYADM/ARF1/WASF3/WASF2/HSP90B1/DLG1/GHRL/TPM1/RND2/PACSIN1/NRP1/RHOF/CLASP2/ASAP3/SHROOM4/DIAPH1/CX3CL1/MIR21/RAPGEF3/PTGER4/ELN/AVIL/OBSL1/CXCL12/COTL1/RND3/AP1AR/RHOJ/PHLDB2/PFN4/DPYSL3/LMOD1/ARHGAP28/RND1/PLEKHH2/WHAMM/ACTN1/WASF1/FAT1/BCAR1/ENAH/EMP2/MYO1C/CAPZA1/TMSB4Y/FCHSD2/NEDD9/CCL21/SFRP1/SORBS1/DIAPH3/NCKAP1/TMSB15A/NOX4/PPM1F/PAK3/MIR214/FAM107A/FLNA/ARPC2/SLIT2/HCLS1/MTOR/CLASP1/DLC1/EFS/TNFAIP1/KANK3/CGNL1/PFN1/FHDC1/CDC42EP5/CORO1A/ARHGEF15/LIMCH1/MAGEL2/SHANK3	88
BP	GO:2001233	regulation of apoptotic signaling pathway	89/2486	406/18670	1.019e-06	0.000141	0.0001105	CLU/MUC1/CTTN/PMAIP1/BCLAF1/CRADD/ACVR1/SLC9A3R1/FAIM2/TNFAIP3/FADD/INHBA/GATA1/BDNF/MFF/SLC25A5/TNF/BCL10/FXN/NOL3/DNAJA1/SFPQ/STRADB/DEDD2/PINK1/PDIA3/PRDX2/HYOU1/MOAP1/HERPUD1/NRP1/FBXW7/ERP29/CX3CL1/MIR21/FLCN/RAF1/BDKRB2/ITPRIP/NFATC4/RNF183/SIRT1/DDIT3/BCL2L1/NME5/CYLD/NOS3/HSPB1/SFRP2/PML/SKIL/IGF1/RELA/CXCL12/DAPK2/TPD52L1/YWHAZ/SERINC3/HNRNPK/PRR7/MMP9/STK4/TIMP3/BMF/MCL1/CREB3L1/NUPR1/IFI6/YAP1/PLAGL2/IL1B/STX4/SFRP1/NONO/MSX1/NR4A2/TP53BP2/PCGF2/CAV1/MADD/RPS7/TRIAP1/BAK1/PDCD5/WFS1/STYXL1/PTPRC/ING5/CIDEB	89
BP	GO:0002063	chondrocyte development	20/2486	48/18670	1.129e-06	0.0001528	0.0001197	COCH/COL6A1/SMPD3/FGF18/SCARA3/ECM1/SFRP2/SERPINH1/COL27A1/SULF1/COL14A1/SOX9/SHOX2/MATN2/VIT/COL12A1/COL21A1/ACAN/VWA1/COL6A2	20
BP	GO:0061298	retina vasculature development in camera-type eye	11/2486	17/18670	1.304e-06	0.0001727	0.0001353	LRP5L/NRP1/COL4A1/RHOJ/PDGFRA/ROM1/PDGFRB/NDP/FZD4/ARHGEF15/LRP5	11
BP	GO:0090288	negative regulation of cellular response to growth factor stimulus	45/2486	166/18670	1.667e-06	0.0002162	0.0001695	LTBP1/SPRY2/HTRA4/PDPK1/HTRA1/VEPH1/CAV2/SMAD7/CD109/TGFB1/SORL1/SPRY1/UBA52/RBPMS2/TWSG1/ZBTB7A/HTRA3/FBN2/MMRN2/SIRT1/SFRP2/SPRY4/SKIL/MIR17HG/TGFB1I1/SULF1/PPM1A/GREM2/CREB3L1/NOTCH1/SFRP1/GPC1/ASPN/UBC/WNT5A/DCN/CAV1/SLIT2/FBN1/RASL11B/HSPA5/MTMR4/ADAMTS12/CHRDL1/PIN1	45
BP	GO:0032535	regulation of cellular component size	82/2486	370/18670	1.702e-06	0.0002162	0.0001695	NRCAM/RHOBTB1/CTTN/ARHGAP18/EPS8/IQGAP3/CIT/FGF13/SLC9A3R1/PPP1R15A/TMOD1/BAG4/MYADM/SEMA3B/ARF1/BDNF/RNF6/PLXNA3/CLNS1A/DLG1/SCT/RAP1GAP2/RND2/CREB1/SEMA3G/NRP1/L1CAM/LRRC8A/FN1/CLN8/SPP1/ELN/VAV1/AVIL/SEMA4D/P2RX7/SLC12A8/ULK2/CXCL12/COTL1/SEMA6D/MSN/SEMA5B/GNB3/AP1AR/MAP2/PFN4/LMOD1/ARHGAP28/PLEKHH2/WHAMM/WASF1/KCNMA1/AQP1/PRR16/MYO1C/CAPZA1/TMSB4Y/FCHSD2/CCL21/CDK5R1/NCKAP1/TMSB15A/VAV3/WNT5A/PAK3/MIR214/WDTC1/ARPC2/HSP90AB1/SLIT2/HCLS1/MTOR/SEMA3E/KANK3/PFN1/CDC42EP5/CORO1A/SIN3A/MAGEL2/SHANK3/GDI1	82
BP	GO:0030324	lung development	46/2486	172/18670	1.931e-06	0.0002391	0.0001874	SPRY2/CHI3L1/ADAMTS2/SIM2/MME/SPARC/ARG1/EP300/LIPA/TBX5/TNF/CREB1/SPRY1/HES1/FBXW7/SMPD3/THRB/FGF18/NFIB/PHEX/SP3/EGFR/LOX/NOS3/PDPN/ITGA3/HSD11B1/PTN/JMJD6/PDGFRA/MIR17HG/IGFBP5/SEC24B/PDGFRB/SOX9/NOTCH1/YAP1/GLI3/ALDH1A2/ZFPM2/SLC23A1/WNT5A/PKDCC/MAN2A1/TNC/CCBE1	46
BP	GO:0051216	cartilage development	53/2486	209/18670	1.959e-06	0.0002391	0.0001874	CHI3L1/COCH/MAF/MEF2D/COL6A1/EVC/SNX19/GHRL/WNT5B/TGFB1/MIR21/SMPD3/SMAD1/FGF18/BMP2/SCARA3/NFIB/ECM1/SFRP2/STC1/SERPINH1/RELA/SATB2/COL27A1/PTH1R/WNT9A/SULF1/COL14A1/THBS3/PRRX1/SOX9/BMP8A/SHOX2/GLI3/HOXA11/MATN2/VIT/ITGB8/COL12A1/COL21A1/WNT5A/EFEMP1/MSX1/ACAN/PKDCC/SIX2/VWA1/COL6A2/MGP/ADAMTS12/SOX6/HOXA3/HYAL1	53
BP	GO:0022604	regulation of cell morphogenesis	101/2486	484/18670	2.132e-06	0.0002552	2e-04	NRCAM/CTTN/ARHGAP18/EPS8/COCH/EPB42/FGF13/SLC9A3R1/GRIP1/PTPRO/MYADM/SEMA3B/SPARC/OLFM4/WASF3/BDNF/TRAK1/RNF6/PLXNA3/BCL11A/LIMS2/DLG1/CRKL/CUX2/FBLIM1/TPM1/RND2/SEMA3G/FMNL1/NRP1/L1CAM/RHOF/FBXW8/ITGA7/DIAPH1/MIR21/FN1/SDC2/YTHDF1/NFATC4/ARHGEF7/SPP1/CCL13/FGD5/NTRK2/SEMA4D/HECW2/OBSL1/SKIL/ULK2/CXCL12/PDPN/SEMA6D/MSN/SEMA5B/ITSN2/PTN/RND3/AP1AR/RHOJ/CHN1/NIN/MAP2/FERMT2/RND1/ZMYM6/HAS2/SHOX2/MYH9/PLXNA1/NEDD9/THY1/CDK5R1/ENPP2/LIMS1/FBLN1/RREB1/WNT5A/FGD3/PAK3/FLNA/PALMD/ARPC2/SLIT2/DLC1/POSTN/KDR/MYH10/FZD4/SEMA3E/ARC/MYCBP2/CDC42EP5/EPHB2/CORO1A/PARVA/SIN3A/ZMYM4/SH3D19/SHANK3/GDI1	101
BP	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	90/2486	419/18670	2.191e-06	0.0002573	0.0002017	CLU/SIRT2/IFI27/PSMD14/PSMD12/SPSB1/ARAF/FBXO33/SEC61B/KEAP1/EDEM1/HSP90B1/SMAD7/KLHL15/PSMD7/PSMB5/KLHL20/ARIH2/HERPUD1/UBA52/RMND5A/ITCH/FBXO38/FBXW7/ERLIN1/UBXN1/SMARCC1/FBXO4/DNAJB14/DNAJC10/USP7/DAB2/SIRT1/DDIT3/WWTR1/UBE2S/DERL1/HECW2/ERLIN2/UCHL1/PML/CBFA2T3/UBE4B/ZFAND2A/MTA1/VCP/BUB1B/WAC/CSNK1A1/RCHY1/ANAPC10/FBXL13/FBXL8/RNF216/PLK3/TRIM2/PSMB7/PLK1/MTM1/STT3B/SPSB3/UBE2C/CAMLG/PSMD1/IL33/PSMD9/SKP2/UBC/UBE2D3/FBXL14/UBE2G2/RNF19B/CHFR/RNF103/ARIH1/TMUB2/HSP90AB1/CAV1/AUP1/TNFAIP1/TAF1/TMEM67/PSME1/PCBP2/WFS1/HSPA5/GIPC1/KIF14/CUL1/SPSB2	90
BP	GO:0007050	cell cycle arrest	58/2486	237/18670	2.26e-06	0.0002582	0.0002024	MUC1/RRAGA/CRADD/RASSF1/PPP1R15A/CNOT8/CNOT4/INHBA/EP300/SLC25A33/APC/EIF2AK4/IRF1/TGFB2/GAS1/STRADB/TGFB1/CDK9/MTBP/CDKN1C/GAS6/HBP1/CCND1/ERN1/CDKN2C/MDM4/DDIT3/PML/SKIL/VASH1/RPRM/IL12A/PPM1A/WHAMM/PLK3/POU4F1/NOTCH1/PRKAG2/NOTCH2/BTG2/FAP/CRLF3/CDKN2B/CDK5R1/MAGI2/DUSP1/CNOT7/HSP90AB1/MTOR/TRIAP1/TNKS1BP1/E2F8/CDC123/UHMK1/BARD1/CDKN3/ZNF268/CNOT1	58
BP	GO:0051056	regulation of small GTPase mediated signal transduction	76/2486	338/18670	2.282e-06	0.0002582	0.0002024	RHOBTB1/SPRY2/ARHGAP18/EPS8/ARHGAP6/TAGAP/SCAI/CSF1/SQSTM1/ARHGEF37/ARFGEF2/TGFB2/CRKL/SRGAP1/RAP1GAP2/LPAR6/SPRY1/KANK2/PSD3/ARHGAP10/AKAP13/NRP1/RHOF/FLCN/RAF1/RALGAPB/ARHGAP9/GPR4/ARHGEF7/FGD5/VAV1/LPAR4/SPRY4/GPR35/CHN2/IGF1/ITGA3/PLEKHG5/ITSN2/ARHGAP32/RHOJ/ARHGAP19/CHN1/CBL/IRS2/ARHGAP28/CDON/FARP1/PDGFRB/NOTCH1/NOTCH2/ARHGAP29/ARHGEF16/DENND4B/VAV3/FGD3/P2RY8/SOS2/ARHGAP30/SLIT2/MADD/LYN/DLC1/ARHGAP11A/TNFAIP1/A2M/CGNL1/MAPKAP1/ARHGEF12/EPHB2/RALGAPA2/ARHGEF15/FBXO8/KIF14/EPS8L1/GDI1	76
BP	GO:0003433	chondrocyte development involved in endochondral bone morphogenesis	13/2486	24/18670	2.382e-06	0.0002648	0.0002076	COCH/COL6A1/SMPD3/SCARA3/SERPINH1/COL27A1/COL14A1/MATN2/VIT/COL12A1/COL21A1/VWA1/COL6A2	13
BP	GO:0071496	cellular response to external stimulus	76/2486	339/18670	2.564e-06	0.0002757	0.0002161	RRAGA/PMAIP1/GABARAPL2/CRADD/NUDT15/MAP1LC3A/FADD/PPARG/ITGA4/KIF26A/DEPDC5/BCL11A/HSP90B1/EIF2AK4/IRF1/JUN/BCL10/LPL/TGFB1/SSH1/LCN2/PPM1D/KANK2/IFI16/PDE2A/CACNB3/GAS6/EIF2S1/STK24/MAP3K14/P2RY12/ZC3H12A/FOS/PTGER4/SIRT1/SESN2/PHEX/MAX/MAP3K2/EGFR/TRIM24/SFRP2/P2RX7/TBL2/MAP3K5/MAP3K1/CADPS2/PTN/CBL/P2RY2/KLF10/SESN3/TMEM150C/AQP1/SOX9/CIB2/IL1B/SFRP1/CDKN2B/SKP2/FAM107A/USP33/NR4A2/MTOR/LYN/POSTN/BAK1/ITGA2/TAF1/HSPA5/PDK4/TNC/PTPRC/NR1H4/AXL/NCOA1	76
BP	GO:0042326	negative regulation of phosphorylation	98/2486	468/18670	2.569e-06	0.0002757	0.0002161	SIRT2/SPRY2/SH2B3/NTF3/SLC9A3R1/PDPK1/PPP1R15B/SH3BP5L/TNFAIP3/MYADM/INHBA/PTPN13/APC/PARD3/PRKAR2A/SNCA/TWIST1/SMAD7/JUN/CD109/DLG1/DUSP10/PPP2CA/DNAJA1/CRKL/TGFB1/PINK1/SORL1/SPRY1/CDKN1C/PRDM15/ITCH/TNIP1/ADARB1/IPO7/PPEF2/CTDSPL/CDKN2C/MIR21/FLCN/ZC3H12A/IGF1R/BDKRB2/ITPRIP/CHMP6/DNAJC10/SIRT1/WWTR1/CYLD/SMCR8/HSPB1/SFRP2/SEMA4D/P2RX7/SPRY4/UCHL1/CBFA2T3/PKIB/CBL/CEACAM1/IRS2/TIMP3/NR2F2/IL2/KLF4/PLK1/NUPR1/PRKAG2/IL1B/IBTK/SFRP1/THY1/CDKN2B/FKBP8/PPM1F/FBLN1/IPO5/PARD6A/DUSP1/CD300A/CAV1/SLIT2/INPP5F/MTOR/LYN/DUSP18/BAK1/RGS14/DMD/MIDN/PRKAR2B/PER1/EPHB2/PTPRC/LRP5/IGFBP3/PIN1/RASSF2	98
BP	GO:0042176	regulation of protein catabolic process	83/2486	381/18670	3.022e-06	0.0003188	0.0002499	CLU/SIRT2/MYLIP/PSMD14/GABARAPL2/ARAF/NUDT15/TNFAIP3/KEAP1/EDEM1/APC/SNCA/TNF/SMAD7/PINK1/SORL1/ARIH2/HERPUD1/RHBDD3/ITCH/TIPARP/FBXW7/ADRA2A/HSP90AA1/UBXN1/SMARCC1/CHMP6/USP7/DAB2/MDM4/EGFR/ECSCR/HECW2/PML/CBFA2T3/RELA/RHBDF1/PLEKHG5/ZFAND2A/MSN/EEF1A1/EGF/VCP/ATG4B/WAC/CSNK1A1/TIMP3/RCHY1/LRIG2/PLK3/BANP/IDE/PLK1/MTM1/NUPR1/SOX9/LAPTM4B/CAMLG/IL1B/PSMD1/IL33/TREM2/TIMP4/WDR91/WNT5A/UBE2G2/FLNA/RNF139/RNF19B/CHFR/AZIN1/ARIH1/HSP90AB1/CAV1/RPS7/TAF1/PSME1/MYCBP2/BARD1/GIPC1/SH3D19/PIN1/LPCAT1	83
BP	GO:0070527	platelet aggregation	22/2486	59/18670	3.113e-06	0.0003229	0.0002531	HBB/ITGB3/MYL9/SH2B3/PEAR1/GATA1/CD9/GAS6/STXBP1/P2RY12/HSPB1/PDPN/PDGFRA/CEACAM1/C1QTNF1/MYH9/FLNA/LYN/METAP1/CSRP1/GP1BA/ABAT	22
BP	GO:0051101	regulation of DNA binding	36/2486	124/18670	3.231e-06	0.0003259	0.0002554	SIRT2/SRI/HJURP/MMP8/PPARG/EP300/GATA1/NFKBIA/TRIM6/NIPBL/TAF10/TWIST1/JUN/TGFB1/IFI16/HES1/FBXW7/ZNF462/IRF4/FOXC1/ZBTB7A/DDIT3/TRAF6/IGF1/EGF/MMP9/RSF1/SMO/POU4F1/KLF4/NSD1/MSX1/ITGA2/TAF1/SIN3A/NEK2	36
BP	GO:0036293	response to decreased oxygen levels	81/2486	370/18670	3.246e-06	0.0003259	0.0002554	SIRT2/ALAS2/PSMD14/PMAIP1/PSMD12/SCFD1/DDAH1/ITPR1/EP300/PLOD2/HSP90B1/TWIST1/NOL3/TGFB2/VEGFC/TGFB1/PSMD7/PINK1/PSMB5/PHB2/TRH/HYOU1/CREB1/CYGB/UBA52/CACNB3/MIR21/CREBBP/RAF1/PAM/BMP2/ANGPTL4/SIRT1/MDM4/SLC2A8/HSD11B2/STC1/PML/TBL2/CBFA2T3/CXCL12/CHCHD2/PTN/RAMP2/CBL/KCNA5/PLAT/FUNDC1/KCNMA1/PLK3/AQP1/PSMB7/CPEB1/KCNK3/CD34/NOTCH1/TEK/PSMD1/SFRP1/ANGPT2/PSMD9/UBC/OXTR/REST/NOX4/MIR214/APOLD1/NR4A2/RYR2/CAV1/STC2/MTOR/POSTN/ITGA2/SOD3/PSME1/CRYAB/MTHFR/PIN1/ABAT/CPEB2	81
BP	GO:0061299	retina vasculature morphogenesis in camera-type eye	8/2486	10/18670	3.426e-06	0.0003386	0.0002653	LRP5L/NRP1/COL4A1/RHOJ/NDP/FZD4/ARHGEF15/LRP5	8
BP	GO:0009952	anterior/posterior pattern specification	54/2486	219/18670	3.916e-06	0.0003809	0.0002985	LRP5L/HOXB5/YY1/EP300/HEYL/PBX1/BHLHE41/HOXA7/CRKL/LDB1/BHLHE40/HIPK1/HES6/HES1/MEOX1/PCSK6/FOXC1/BMP2/DDIT3/SFRP2/ACVR2A/HOXC10/HOXC6/HOXB7/HOXD8/NR2F2/HOXA10/CDON/SMO/FRS2/MEOX2/NOTCH1/GLI3/HOXA11/HOXC9/BTG2/SFRP1/ALDH1A2/FZD5/BPTF/WNT5A/MSX1/EMX2/TBX1/SSBP3/PCGF2/SIX2/HOXA9/PALB2/HOXC5/ARC/HOXA3/LRP5/HOXD9	54
BP	GO:0006913	nucleocytoplasmic transport	76/2486	343/18670	4.057e-06	0.0003826	0.0002999	IFI27/RBM4/SRRM1/NXF3/FAM53B/EIF5A/MBTPS1/RBM22/ANKLE1/NFKBIA/NXT1/AKAP8L/YTHDC1/SARNP/NUP93/IPO9/STRADB/DHX9/TGFB1/RPS15/THOC2/PHB2/HEATR3/AKAP13/GAS6/RSRC1/U2AF1L4/IPO7/NOLC1/DDX19A/ZC3H12A/RAPGEF3/NUP50/KPNA1/JUP/PML/SLBP/NUP153/U2AF1/NUP210/GEMIN6/PABPN1/KPNA3/RAE1/NUP188/NUP160/SNRPB/NUP54/PPM1A/NXF1/NUP214/SMO/NUP155/RPAIN/MCM3AP/GLI3/IL1B/KHDRBS1/PTPN14/RANGAP1/SMG6/TNPO3/IPO5/FLNA/SIX2/HCLS1/RGS14/KPNA4/ANP32B/UHMK1/POLR2D/BARD1/ABCE1/SETD2/HSPA9/LZTS2	76
BP	GO:0032956	regulation of actin cytoskeleton organization	76/2486	343/18670	4.057e-06	0.0003826	0.0002999	RHOBTB1/CTTN/ARHGAP18/EPS8/NTF3/CIT/ARHGAP6/TMOD1/BAG4/MYADM/ARF1/WASF2/DLG1/TGFB1/TPM1/RND2/AKAP13/NRP1/RHOF/CLASP2/ASAP3/CX3CL1/MIR21/PAM/RAPGEF3/PTGER4/ELN/AVIL/CXCL12/COTL1/RND3/AP1AR/RHOJ/PDGFRA/PHLDB2/FZD10/PFN4/LMOD1/ARHGAP28/RND1/PLEKHH2/WHAMM/WASF1/PDGFRB/MYO1C/CAPZA1/NOTCH2/TMSB4Y/TEK/FCHSD2/CCL21/SFRP1/CDK5R1/NCKAP1/TMSB15A/NOX4/PPM1F/PAK3/MIR214/FAM107A/FLNA/ARPC2/SLIT2/HCLS1/MTOR/CLASP1/DLC1/SEMA3E/KANK3/PFN1/CDC42EP5/CORO1A/ARHGEF15/LIMCH1/MAGEL2/SHANK3	76
BP	GO:0051168	nuclear export	49/2486	194/18670	5.294e-06	0.0004918	0.0003855	IFI27/SRRM1/NXF3/EIF5A/RBM22/ANKLE1/NXT1/AKAP8L/YTHDC1/SARNP/NUP93/STRADB/DHX9/TGFB1/RPS15/THOC2/AKAP13/GAS6/U2AF1L4/DDX19A/RAPGEF3/NUP50/SLBP/NUP153/U2AF1/NUP210/PABPN1/RAE1/NUP188/NUP160/NUP54/PPM1A/NXF1/NUP214/NUP155/MCM3AP/IL1B/KHDRBS1/PTPN14/RANGAP1/SMG6/ANP32B/UHMK1/POLR2D/BARD1/ABCE1/SETD2/HSPA9/LZTS2	49
BP	GO:0030099	myeloid cell differentiation	88/2486	416/18670	5.396e-06	0.000494	0.0003872	ALAS2/MYL9/KLF13/C1QC/SH2B3/EPB42/INPP5D/PABPC4/FADD/PPARG/SLC4A1/IRF8/CNOT4/INHBA/EP300/GATA1/NFKBIA/CSF1/WASF2/PRKCB/L3MBTL3/TNF/JUN/CD109/HOXA7/TRIM58/LTF/IREB2/TGFB1/TAL1/LDB1/AHSP/CREB1/TNRC6B/ZFP36/IFI16/CDKN1C/ARID4A/FBXW7/WDR5/BATF2/CREBBP/IRF4/ZBTB7A/FOS/CEBPE/SIRT1/JAGN1/SP3/TRAF6/LOX/IL23R/BATF/MEIS2/PML/ACVR2A/CBFA2T3/PIR/HOXB7/JMJD6/TNFRSF11A/CEACAM1/MMP9/KLF10/PIK3CD/FLI1/ACTN1/POU4F1/RAB7B/NOTCH2/MYH9/SFRP1/CDKN2B/TREM2/HCLS1/MTOR/LYN/BATF3/HOXA9/FBN1/GP1BA/KLF1/JUNB/NCOA6/SOX6/SIN3A/HSPA9/RASSF2	88
BP	GO:0051169	nuclear transport	76/2486	346/18670	5.673e-06	0.0005066	0.000397	IFI27/RBM4/SRRM1/NXF3/FAM53B/EIF5A/MBTPS1/RBM22/ANKLE1/NFKBIA/NXT1/AKAP8L/YTHDC1/SARNP/NUP93/IPO9/STRADB/DHX9/TGFB1/RPS15/THOC2/PHB2/HEATR3/AKAP13/GAS6/RSRC1/U2AF1L4/IPO7/NOLC1/DDX19A/ZC3H12A/RAPGEF3/NUP50/KPNA1/JUP/PML/SLBP/NUP153/U2AF1/NUP210/GEMIN6/PABPN1/KPNA3/RAE1/NUP188/NUP160/SNRPB/NUP54/PPM1A/NXF1/NUP214/SMO/NUP155/RPAIN/MCM3AP/GLI3/IL1B/KHDRBS1/PTPN14/RANGAP1/SMG6/TNPO3/IPO5/FLNA/SIX2/HCLS1/RGS14/KPNA4/ANP32B/UHMK1/POLR2D/BARD1/ABCE1/SETD2/HSPA9/LZTS2	76
BP	GO:0072006	nephron development	39/2486	142/18670	5.696e-06	0.0005066	0.000397	PTPRO/IRX2/HEYL/PBX1/DLG1/TGFB1/HES1/FOXC1/BMP2/IRX3/GPR4/WWTR1/NPNT/MTSS1/ITGA3/SIX1/HOXB7/PDGFRA/NUP160/SULF1/SMO/PDGFRB/SOX9/CD34/NOTCH1/YAP1/GLI3/HOXA11/TEK/ANGPT2/ADAMTS16/MAGI2/PODXL/SIX2/GZF1/ACTA2/ENPEP/NOTCH3/LZTS2	39
BP	GO:0006446	regulation of translational initiation	26/2486	79/18670	6.132e-06	0.0005292	0.0004148	RBM4/EIF5/PPP1R15A/PPP1R15B/PAIP2B/EIF4B/EIF2AK4/TNF/YTHDF2/EIF2S1/LARP1/EIF1/PAIP2/YTHDF1/HSPB1/EIF4H/POLR2G/KHDRBS1/MIF4GD/YTHDF3/EIF3K/MTOR/CDC123/UHMK1/POLR2D/EIF2B2	26
BP	GO:0003422	growth plate cartilage morphogenesis	11/2486	19/18670	6.154e-06	0.0005292	0.0004148	COCH/COL6A1/SCARA3/STC1/COL14A1/MATN2/VIT/COL12A1/COL21A1/VWA1/COL6A2	11
BP	GO:0051099	positive regulation of binding	46/2486	179/18670	6.206e-06	0.0005292	0.0004148	SIRT2/MMP8/PPARG/EP300/BDNF/TRIM6/NIPBL/TWIST1/PPP2CA/SPPL3/DHX9/TGFB1/CDK9/TRAF4/HES1/NRP1/ACE/EIF2S1/PARP9/IRF4/FOXC1/BMP2/DDX11/TRAF6/DERL1/IGF1/EGF/MFNG/MMP9/STK4/POU4F1/KLF4/DTX3L/CTHRC1/WNT5A/USP33/HSP90AB1/EBF2/CAV1/ITGA2/TAF1/GPSM1/SPON1/HOXA3/PIN1/LARP6	46
BP	GO:0030168	platelet activation	41/2486	153/18670	6.466e-06	0.0005439	0.0004263	HBB/ITGB3/MYL9/SH2B3/PDPK1/ITPR1/PEAR1/GATA1/PRKCB/CD9/SELP/VWF/GAS6/STXBP1/ADRA2A/RAF1/P2RY12/NOS3/VAV1/HSPB1/TREML1/F8/PDPN/YWHAZ/PDGFRA/CEACAM1/DGKD/C1QTNF1/MYH9/VAV3/FLNA/GNA14/DGKZ/LYN/METAP1/CSRP1/GP1BA/AXL/C1GALT1C1/ABAT/COL1A2	41
BP	GO:0001666	response to hypoxia	78/2486	359/18670	6.571e-06	0.0005454	0.0004275	SIRT2/ALAS2/PSMD14/PMAIP1/PSMD12/SCFD1/DDAH1/ITPR1/EP300/PLOD2/HSP90B1/TWIST1/NOL3/TGFB2/VEGFC/TGFB1/PSMD7/PINK1/PSMB5/PHB2/TRH/HYOU1/CREB1/CYGB/UBA52/MIR21/CREBBP/RAF1/PAM/BMP2/ANGPTL4/SIRT1/MDM4/SLC2A8/HSD11B2/STC1/PML/TBL2/CBFA2T3/CXCL12/CHCHD2/PTN/RAMP2/KCNA5/PLAT/FUNDC1/KCNMA1/PLK3/AQP1/PSMB7/CPEB1/KCNK3/CD34/NOTCH1/TEK/PSMD1/SFRP1/ANGPT2/PSMD9/UBC/REST/NOX4/MIR214/APOLD1/NR4A2/RYR2/CAV1/STC2/MTOR/POSTN/ITGA2/SOD3/PSME1/CRYAB/MTHFR/PIN1/ABAT/CPEB2	78
BP	GO:0002576	platelet degranulation	36/2486	128/18670	7.175e-06	0.0005877	0.0004606	CLU/PROS1/FAM49B/ITGB3/ORM1/OLA1/SYTL4/SPARC/LGALS3BP/CD9/CD109/TGFB2/VEGFC/TGFB1/SELP/VWF/GAS6/STXBP1/FN1/SERPING1/ECM1/RARRES2/MMRN1/F8/IGF1/EGF/F13A1/TIMP3/ACTN1/ISLR/SERPINA3/TAGLN2/FLNA/LYN/A2M/CLEC3B	36
BP	GO:0019080	viral gene expression	48/2486	191/18670	7.613e-06	0.0006154	0.0004824	RPS27/RPS28/EP300/EIF3L/EIF2AK4/JUN/NUP93/DHX9/IFITM3/CDK9/RPS15/TRIM21/ZFP36/UBA52/DENR/RPS26/RPLP1/CHD1/RPL28/RPS3A/NUP50/RPL10/EIF3F/CCNT2/RPL29/POLR2G/NUP153/NUP210/RAE1/NUP188/RPS8/RPS4Y1/NUP160/RSF1/RPS2/NUP54/RPL39/RPS10/NUP214/NUP155/RPL6/REST/RPL14/RPS7/PCBP2/POLR2D/RPL9/RPL15	48
BP	GO:0001101	response to acid chemical	75/2486	343/18670	7.733e-06	0.0006171	0.0004837	RRAGA/TOMM20/PPARG/YY1/SPARC/ARG1/COL6A1/BCL11A/CD9/TNF/LPL/WNT5B/CDO1/PINK1/IGFBP2/PHB2/RXRB/CREB1/CYP26B1/ZC3H12A/COL16A1/NFATC4/COL18A1/PTGER4/SESN2/EGFR/BCL2L1/NTRK2/ADCY6/RELA/PTN/ASS1/SIX1/COL4A1/PTGFR/PDGFRA/AKR1C2/WNT9A/FZD10/LRP11/SESN3/GDAP2/AQP1/CPEB1/KLF4/PDGFRB/SOX9/TIE1/YAP1/CPS1/CCL21/SFRP1/ALDH1A2/IPO5/WNT5A/DUSP1/TBX1/AKAP8/MTOR/LYN/KDR/ITGA2/FZD4/GLRB/PDK4/TNC/MGMT/NR1H4/FABP3/COL5A2/NQO1/MTHFR/HMGCL/NCOA1/COL1A2	75
BP	GO:0050900	leukocyte migration	101/2486	499/18670	8.539e-06	0.0006729	0.0005274	PROS1/ITGB3/CXCL5/EPS8/INPP5D/EDNRB/CD177/PTPRO/FADD/ITGA4/GYPB/CSF1/LYST/CD9/TNF/FLT1/HSD3B7/HOXA7/ESAM/TGFB2/ATP1B2/CRKL/VEGFC/IL1R1/MMP1/AKIRIN1/CD244/TGFB1/ELANE/CH25H/SELP/GAS6/GRB14/L1CAM/CX3CL1/SMPD3/P2RY12/FN1/PLVAP/CXCR1/PDE4B/SDC2/PTGER4/EDN3/THBS4/JAGN1/CCL13/ECM1/VAV1/JAM2/RARRES2/ITGA9/CD48/CEACAM6/CXCL12/DAPK2/MTUS1/ITGA3/MSN/PTN/CEACAM8/CXCL6/PLCB1/TNFRSF11A/STK10/CEACAM1/PIK3CD/ITGAL/HRH1/IL12A/SLC7A9/TNFRSF14/CD34/MYH9/IL1B/TEK/CCL21/IL33/THY1/TREM2/GPC1/ANGPT2/CXCL1/VAV3/WNT5A/CCL8/DUSP1/CD300A/CAV1/SLIT2/GYPA/LYN/SPN/ITGA2/GPR15/MST1/CORO1A/CCL18/XG/DOCK8/COL1A2	101
BP	GO:0034333	adherens junction assembly	28/2486	90/18670	9.273e-06	0.0007216	0.0005655	TRIP6/CTTN/ARHGAP6/PDPK1/SMAD7/LDB1/HIPK1/NRP1/CLASP2/COL16A1/ARHGEF7/RAMP2/PHLDB2/FERMT2/WHAMM/ACTN1/TEK/SFRP1/SORBS1/THY1/LIMS1/PPM1F/FAM107A/CLASP1/DLC1/KDR/ITGA2/LIMCH1	28
BP	GO:0003413	chondrocyte differentiation involved in endochondral bone morphogenesis	14/2486	30/18670	9.487e-06	0.0007291	0.0005714	COCH/COL6A1/SMPD3/SCARA3/SERPINH1/COL27A1/COL14A1/SOX9/MATN2/VIT/COL12A1/COL21A1/VWA1/COL6A2	14
BP	GO:0060541	respiratory system development	49/2486	198/18670	9.668e-06	0.000734	0.0005753	SPRY2/CHI3L1/ADAMTS2/SIM2/MME/SPARC/ARG1/EP300/LIPA/TBX5/TNF/CREB1/SPRY1/HES1/FBXW7/SMPD3/THRB/FGF18/NFIB/PHEX/SP3/EGFR/LOX/NOS3/PDPN/ITGA3/HSD11B1/PTN/ASS1/SIX1/JMJD6/PDGFRA/MIR17HG/IGFBP5/SEC24B/PDGFRB/SOX9/NOTCH1/YAP1/ALDH1A3/GLI3/ALDH1A2/ZFPM2/SLC23A1/WNT5A/PKDCC/MAN2A1/TNC/CCBE1	49
BP	GO:0034446	substrate adhesion-dependent cell spreading	30/2486	100/18670	1.016e-05	0.0007581	0.0005941	ITGB3/ITGA4/MYADM/OLFM4/LIMS2/CRKL/LAMC1/NRP1/FN1/LAMC2/ARHGEF7/PDPN/AP1AR/FERMT2/HAS2/TEK/NEDD9/LAMB1/LIMS1/FBLN1/RREB1/FLNA/ARPC2/NTN4/POSTN/FZD4/RADIL/PARVA/AXL/KIF14	30
BP	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	26/2486	81/18670	1.023e-05	0.0007581	0.0005941	LTBP1/HTRA4/PDPK1/HTRA1/VEPH1/CAV2/SMAD7/CD109/TGFB1/UBA52/ZBTB7A/HTRA3/FBN2/SIRT1/SKIL/MIR17HG/TGFB1I1/PPM1A/ASPN/UBC/CAV1/FBN1/RASL11B/HSPA5/MTMR4/PIN1	26
BP	GO:0022612	gland morphogenesis	34/2486	120/18670	1.071e-05	0.0007828	0.0006135	LRP5L/SLC9A3R1/POLB/TNFAIP3/ARG1/CSF1/TNF/LIMS2/TGFB2/TGFB1/PHB2/NRP1/FBXW7/TWSG1/NFIB/EGFR/PML/MSN/PTN/CEACAM1/IGFBP5/SULF1/FRS2/SOX9/TBX2/NOTCH1/GLI3/PLXNA1/SFRP1/WNT5A/CAV1/NTN4/TNC/LRP5	34
BP	GO:0045216	cell-cell junction organization	41/2486	156/18670	1.081e-05	0.0007828	0.0006135	CLDN5/CD177/PTPRO/MPP5/APC/PARD3/RAB13/CD9/TNF/PARD6G/LIMS2/DLG1/ESAM/TGFB2/TGFB1/ACE/PLEKHA7/GJA5/FLCN/GJA4/JUP/CDH26/RAMP2/NPHP1/SDK1/PKP4/MYO1C/MPP7/FZD5/ANK2/LIMS1/PKN2/TJP1/PARD6A/CDH5/CAV1/NLGN4X/CDH6/NR1H4/PARD6B/CDH11	41
BP	GO:0048706	embryonic skeletal system development	35/2486	126/18670	1.287e-05	0.0009205	0.0007215	HOXB5/NIPBL/PBX1/TWIST1/DLG1/HOXA7/WDR19/SP3/KIAA1217/ACVR2A/HOXC6/SATB2/SIX1/HOXB7/PDGFRA/WNT9A/SULF1/PRRX1/IFT140/SHOX2/GLI3/HOXA11/HOXC9/TBX15/WNT5A/MBTD1/TBX1/PCGF2/SIX2/HOXA9/HOXC5/HOXA3/SETD2/HYAL1/HOXD9	35
BP	GO:0060350	endochondral bone morphogenesis	24/2486	73/18670	1.408e-05	0.0009788	0.0007672	COCH/MEF2D/COL6A1/TMEM119/SMPD3/FOXC1/FGF18/ALPL/SCARA3/STC1/SERPINH1/COL27A1/COL14A1/THBS3/SOX9/SHOX2/HOXA11/MATN2/TEK/VIT/COL12A1/COL21A1/VWA1/COL6A2	24
BP	GO:0006611	protein export from nucleus	45/2486	179/18670	1.431e-05	0.0009788	0.0007672	IFI27/SRRM1/NXF3/EIF5A/RBM22/ANKLE1/NXT1/AKAP8L/YTHDC1/SARNP/NUP93/STRADB/TGFB1/RPS15/THOC2/GAS6/U2AF1L4/DDX19A/RAPGEF3/NUP50/SLBP/NUP153/U2AF1/NUP210/PABPN1/RAE1/NUP188/NUP160/NUP54/PPM1A/NXF1/NUP214/NUP155/MCM3AP/IL1B/PTPN14/RANGAP1/SMG6/ANP32B/UHMK1/POLR2D/BARD1/ABCE1/SETD2/HSPA9	45
BP	GO:0008361	regulation of cell size	45/2486	179/18670	1.431e-05	0.0009788	0.0007672	NRCAM/CTTN/IQGAP3/FGF13/SLC9A3R1/SEMA3B/BDNF/RNF6/PLXNA3/CLNS1A/SCT/RAP1GAP2/RND2/CREB1/SEMA3G/NRP1/L1CAM/LRRC8A/FN1/CLN8/SPP1/VAV1/SEMA4D/P2RX7/SLC12A8/ULK2/CXCL12/SEMA6D/MSN/SEMA5B/GNB3/MAP2/KCNMA1/AQP1/PRR16/CDK5R1/VAV3/WNT5A/WDTC1/HSP90AB1/MTOR/SEMA3E/SIN3A/SHANK3/GDI1	45
BP	GO:2001235	positive regulation of apoptotic signaling pathway	45/2486	179/18670	1.431e-05	0.0009788	0.0007672	PMAIP1/BCLAF1/CRADD/SLC9A3R1/FADD/INHBA/MFF/BCL10/SFPQ/DEDD2/PINK1/PDIA3/MOAP1/FBXW7/FLCN/NFATC4/RNF183/SIRT1/DDIT3/BCL2L1/CYLD/PML/SKIL/TPD52L1/YWHAZ/SERINC3/PRR7/MMP9/STK4/TIMP3/BMF/MCL1/NUPR1/PLAGL2/SFRP1/MSX1/TP53BP2/CAV1/RPS7/BAK1/PDCD5/STYXL1/PTPRC/ING5/CIDEB	45
BP	GO:0002237	response to molecule of bacterial origin	74/2486	343/18670	1.45e-05	0.0009808	0.0007687	SIRT2/SLPI/CXCL5/JUND/TNFAIP3/EDNRB/CTSG/NFKBIB/IRF8/SPARC/ARG1/NFKB2/NFKBIA/TRIM6/SNCA/HPGD/TNF/JUN/DUSP10/BCL10/LTF/TGFB1/ELANE/LCN2/PRDX2/SELP/ZFP36/FCGR2B/CX3CL1/MIR21/ZC3H12A/ALPL/PDE4B/FOS/PTGER4/CEBPE/TRAF6/GCH1/IL23R/NOS3/P2RX7/RELA/PLSCR4/LIAS/ASS1/PABPN1/PTGFR/CXCL6/LOXL1/TFPI/TNFRSF11A/GJB6/PDCD1LG2/IL12A/NOTCH1/ACP5/IL1B/CPS1/TREM2/TIMP4/FZD5/SSC5D/CXCL1/WNT5A/DCN/TLR9/GNG12/AKAP8/IL10RA/LYN/JUNB/NR1H4/AXL/NLRP7	74
BP	GO:0048863	stem cell differentiation	59/2486	257/18670	1.546e-05	0.001034	0.0008106	PSMD14/PSMD12/ACVR1/PEF1/EDNRB/SEMA3B/GATA1/TRIM6/TBX5/TWIST1/YTHDF2/HOXA7/TGFB2/PSMD7/TAL1/PSMB5/LDB1/SEMA3G/PHACTR4/HES1/MEOX1/NRP1/ITCH/ACE/NOLC1/FN1/FOXC1/EDN3/BATF/SEMA4D/SEMA6D/SEMA5B/PTN/PDGFRA/SMO/PSMB7/SOX9/TBX2/NOTCH1/YAP1/JARID2/PSMD1/SFRP1/ALDH1A2/PSMD9/ZNF281/REST/MSX1/CHD2/TBX1/SEMA3E/PSME1/A2M/SOX6/PTPRC/TCOF1/CDK13/SETD2/HSPA9	59
BP	GO:0051017	actin filament bundle assembly	40/2486	153/18670	1.575e-05	0.001034	0.0008106	EPS8/AIF1L/ITGB5/ARHGAP6/BAG4/WASF2/HSP90B1/TPM1/RND2/NRP1/RHOF/CLASP2/ASAP3/CX3CL1/MIR21/RAPGEF3/PTGER4/ELN/RND3/PHLDB2/DPYSL3/ARHGAP28/RND1/ACTN1/NEDD9/SFRP1/SORBS1/NOX4/PPM1F/FAM107A/FLNA/MTOR/CLASP1/DLC1/TNFAIP1/PFN1/FHDC1/ARHGEF15/LIMCH1/SHANK3	40
BP	GO:0060351	cartilage development involved in endochondral bone morphogenesis	18/2486	47/18670	1.578e-05	0.001034	0.0008106	COCH/COL6A1/SMPD3/SCARA3/STC1/SERPINH1/COL27A1/COL14A1/THBS3/SOX9/SHOX2/HOXA11/MATN2/VIT/COL12A1/COL21A1/VWA1/COL6A2	18
BP	GO:1903845	negative regulation of cellular response to transforming growth factor beta stimulus	26/2486	83/18670	1.668e-05	0.001082	0.0008477	LTBP1/HTRA4/PDPK1/HTRA1/VEPH1/CAV2/SMAD7/CD109/TGFB1/UBA52/ZBTB7A/HTRA3/FBN2/SIRT1/SKIL/MIR17HG/TGFB1I1/PPM1A/ASPN/UBC/CAV1/FBN1/RASL11B/HSPA5/MTMR4/PIN1	26
BP	GO:0097191	extrinsic apoptotic signaling pathway	53/2486	224/18670	1.692e-05	0.001086	0.0008511	IFI27/CTTN/PMAIP1/CRADD/ACVR1/MKNK2/PDPK1/FAIM2/TNFAIP3/FADD/INHBA/GATA1/TNF/BCL10/NOL3/TGFB2/STRADB/TGFB1/DEDD2/PDIA3/LCN2/PRDX2/MOAP1/HIPK1/NRP1/CX3CL1/RAF1/ITPRIP/BCL2L1/CYLD/NOS3/SFRP2/P2RX7/PML/SKIL/IGF1/RELA/STK4/TIMP3/IL12A/IL2/MCL1/IFI6/YAP1/DIABLO/IL1B/STX4/SFRP1/IL33/CAV1/MADD/BAK1/PTPRC	53
BP	GO:0009896	positive regulation of catabolic process	87/2486	423/18670	1.888e-05	0.001199	0.0009397	CLU/SIRT2/MYLIP/VPS13C/TNFAIP3/KEAP1/EDEM1/CNOT8/APC/EIF2AK4/SNCA/TNF/TWIST1/SMAD7/YTHDF2/SCT/PINK1/SORL1/PFKFB2/TNRC6B/TRIM21/ZFP36/ARIH2/HERPUD1/RHBDD3/ITCH/TIPARP/FBXW7/ADRA2A/LARP1/HSP90AA1/FLCN/ZC3H12A/RAB3GAP2/DAB2/SIRT1/SESN2/ECSCR/SMCR8/P2RX7/HECW2/CBFA2T3/IGF1/POLR2G/ZFAND2A/MSN/FYCO1/EGF/VCP/ATG4B/WAC/CSNK1A1/IRS2/RCHY1/SESN3/PLK3/IDE/PLK1/NUPR1/SOX9/LRSAM1/DTX3L/IL1B/RAB12/BTG2/IL33/TREM2/UVRAG/WNT5A/DCN/YTHDF3/RNF139/RNF19B/CHFR/ARIH1/CNOT7/CAV1/KDR/TAF1/GPSM1/RC3H1/BARD1/HSPB8/SCOC/SH3D19/CNOT1/LPCAT1	87
BP	GO:2001242	regulation of intrinsic apoptotic signaling pathway	42/2486	165/18670	1.975e-05	0.001242	0.0009732	CLU/MUC1/PMAIP1/BCLAF1/SLC9A3R1/NOL3/DNAJA1/SFPQ/PINK1/HYOU1/HERPUD1/FBXW7/ERP29/MIR21/FLCN/BDKRB2/RNF183/SIRT1/DDIT3/BCL2L1/NME5/CYLD/HSPB1/SFRP2/SKIL/CXCL12/DAPK2/SERINC3/HNRNPK/MMP9/BMF/MCL1/CREB3L1/NUPR1/PLAGL2/NONO/MSX1/CAV1/RPS7/TRIAP1/WFS1/STYXL1	42
BP	GO:0002819	regulation of adaptive immune response	41/2486	160/18670	2.081e-05	0.001295	0.001015	FAM49B/CD1C/TNFAIP3/FADD/PARP3/ARG1/EIF2AK4/IRF1/ADCY7/TNF/SMAD7/DUSP10/IL1R1/TGFB1/FBXO38/FCGR2B/MIR21/ZC3H12A/CD1B/NFKBIZ/HLX/BTK/SIRT1/EXOSC3/TRAF6/IL23R/P2RX7/CD48/HLA-B/CEACAM1/IL12A/IL2/TNFRSF14/IL1B/IL33/PPP3CB/FZD5/RC3H1/PTPRC/RSAD2/HLA-A	41
BP	GO:0071229	cellular response to acid chemical	50/2486	209/18670	2.114e-05	0.001296	0.001016	RRAGA/PPARG/COL6A1/BCL11A/TNF/LPL/WNT5B/PINK1/PHB2/CREB1/CYP26B1/ZC3H12A/COL16A1/NFATC4/PTGER4/SESN2/EGFR/BCL2L1/NTRK2/ADCY6/ASS1/SIX1/COL4A1/PTGFR/PDGFRA/AKR1C2/WNT9A/FZD10/SESN3/AQP1/CPEB1/KLF4/SOX9/YAP1/CPS1/SFRP1/ALDH1A2/IPO5/WNT5A/TBX1/AKAP8/MTOR/LYN/KDR/FZD4/PDK4/TNC/NR1H4/COL5A2/COL1A2	50
BP	GO:0085029	extracellular matrix assembly	13/2486	28/18670	2.124e-05	0.001296	0.001016	TNXB/TGFB1/GAS6/EFEMP2/SMPD3/LOX/HAS2/SOX9/NOTCH1/HAS3/HAS1/MFAP4/COL1A2	13
BP	GO:0003170	heart valve development	21/2486	61/18670	2.172e-05	0.001302	0.001021	ACVR1/HEYL/TBX5/TWIST1/TGFB2/TGFB1/PDE2A/GJA5/MATR3/BMP2/MDM4/ELN/NOS3/ADAMTS9/SOX9/NOTCH1/SHOX2/NOTCH2/HECTD1/SLIT2/MTOR	21
BP	GO:0007599	hemostasis	73/2486	341/18670	2.175e-05	0.001302	0.001021	HBB/PROS1/ITGB3/HBD/MYL9/SH2B3/PDPK1/ITPR1/CD177/PEAR1/PABPC4/SLC4A1/GATA1/PROC/PRKCB/PRKAR2A/CD9/IRF1/CD59/CYP4F2/PRDX2/SELP/VWF/GAS6/STXBP1/ADRA2A/RAF1/P2RY12/EHD2/SERPING1/NOS3/VAV1/HSPB1/TREML1/P2RX7/MMRN1/F8/PDPN/YWHAZ/F13A1/TFPI/PDGFRA/CEACAM1/DGKD/FLI1/PLAT/C1QTNF1/CAPZA1/CD34/JMJD1C/MYH9/FAP/ZFPM2/VAV3/FBLN1/PHF21A/FLNA/GNA14/CAV1/DGKZ/LYN/METAP1/ITGA2/CSRP1/GP1BA/A2M/PRKAR2B/DOCK11/DOCK8/AXL/C1GALT1C1/ABAT/COL1A2	73
BP	GO:0032102	negative regulation of response to external stimulus	77/2486	365/18670	2.251e-05	0.001335	0.001046	PROS1/SIRT2/SH2B3/TNFAIP3/ARG2/PTPRO/PPARG/HTRA1/SEMA3B/RGMA/C5orf30/PROC/PLXNA3/FEM1A/CD9/PGLYRP1/ADCY7/CD109/DUSP10/LTF/GHRL/RTN4RL1/ELANE/PRDX2/SEMA3G/KANK2/CACNB3/NRP1/ITCH/CLASP2/GPATCH3/FCGR2B/CX3CL1/ZC3H12A/PTGER4/SPP1/SERPING1/CALCRL/NOS3/SEMA4D/WFDC1/IGF1/SEMA6D/SEMA5B/TSPAN6/TFPI/NENF/PDGFRA/CEACAM1/PHLDB2/NR1D2/PLAT/LRIG2/C1QTNF1/IL2/KLF4/CD34/NOTCH1/ACP5/TEK/FAP/ANGPT2/RNF125/WNT5A/DUSP1/CDH5/SLIT2/INPP5F/CLASP1/ADCYAP1/SEMA3E/PCBP2/GP1BA/PTPRC/NR1H4/ABAT/NLRP7	77
BP	GO:1903829	positive regulation of cellular protein localization	70/2486	324/18670	2.324e-05	0.001362	0.001068	ABLIM3/PMAIP1/PDPK1/STOM/GAS8/RBM22/EDEM1/CLIP3/APC/MFF/NIPBL/SQSTM1/TNF/DLG1/TGFB1/SSH1/PINK1/SORL1/ARIH2/CACNB3/GAS6/FBXW7/PARP9/ZC3H12A/RAPGEF3/SESN2/JUP/EGFR/STAC/CYLD/SEC16A/ITGA3/CARD10/MSN/YWHAZ/EGF/PTN/STAC2/LRIG2/PPM1A/SMO/RAMP3/GLIS2/PLK3/CCT8/PLK1/MYO1C/DTX3L/GLI3/IL1B/STX4/ZFAND1/SORBS1/TREM2/ARHGEF16/FZD5/CDK5R1/UBE2D3/PDCD10/IPO5/FLNA/PARD6A/TP53BP2/HSP90AB1/HCLS1/SLC35D3/PDCD5/ANP32B/EPHB2/SYT11	70
BP	GO:1904467	regulation of tumor necrosis factor secretion	14/2486	32/18670	2.369e-05	0.001362	0.001068	ORM1/MMP8/ARG2/LPL/GHRL/DHX9/CX3CL1/ZC3H12A/IFIH1/FZD5/WNT5A/FRMD8/NR1H4/SYT11	14
BP	GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	30/2486	104/18670	2.369e-05	0.001362	0.001068	ACVR1/PELO/INHBA/EP300/TGFB2/NUP93/TGFB1/HES1/CDKN1C/TWSG1/FLCN/CREBBP/BMP2/DAB2/NPNT/ACVR2A/INHBE/TGFB1I1/SULF1/BMP8A/NOTCH1/RBPMS/CDKN2B/ZNF423/FKBP8/MSX1/CDH5/HSP90AB1/TTK/GIPC1	30
BP	GO:0007596	blood coagulation	72/2486	336/18670	2.386e-05	0.001362	0.001068	HBB/PROS1/ITGB3/HBD/MYL9/SH2B3/PDPK1/ITPR1/CD177/PEAR1/PABPC4/SLC4A1/GATA1/PROC/PRKCB/PRKAR2A/CD9/IRF1/CD59/CYP4F2/PRDX2/SELP/VWF/GAS6/STXBP1/ADRA2A/RAF1/P2RY12/EHD2/SERPING1/NOS3/VAV1/HSPB1/TREML1/P2RX7/MMRN1/F8/PDPN/YWHAZ/F13A1/TFPI/PDGFRA/CEACAM1/DGKD/PLAT/C1QTNF1/CAPZA1/CD34/JMJD1C/MYH9/FAP/ZFPM2/VAV3/FBLN1/PHF21A/FLNA/GNA14/CAV1/DGKZ/LYN/METAP1/ITGA2/CSRP1/GP1BA/A2M/PRKAR2B/DOCK11/DOCK8/AXL/C1GALT1C1/ABAT/COL1A2	72
BP	GO:0072073	kidney epithelium development	37/2486	140/18670	2.494e-05	0.001409	0.001104	ARG2/PTPRO/IRX2/HEYL/PBX1/SMAD7/DLG1/TGFB1/SPRY1/KANK2/HES1/CRLF1/SMAD1/FOXC1/BMP2/IRX3/WWTR1/NPNT/MTSS1/SIX1/HOXB7/EFNB2/SMO/SOX9/CD34/NOTCH1/YAP1/GLI3/HOXA11/SFRP1/ADAMTS16/MAGI2/PODXL/SIX2/SLIT2/GZF1/LZTS2	37
BP	GO:0110053	regulation of actin filament organization	59/2486	261/18670	2.512e-05	0.001409	0.001104	RHOBTB1/CTTN/ARHGAP18/EPS8/CIT/ARHGAP6/TMOD1/BAG4/MYADM/ARF1/WASF2/DLG1/TPM1/NRP1/CLASP2/ASAP3/CX3CL1/MIR21/RAPGEF3/PTGER4/ELN/AVIL/CXCL12/COTL1/AP1AR/PHLDB2/PFN4/LMOD1/ARHGAP28/PLEKHH2/WHAMM/WASF1/MYO1C/CAPZA1/TMSB4Y/FCHSD2/CCL21/SFRP1/NCKAP1/TMSB15A/NOX4/PPM1F/PAK3/MIR214/FLNA/ARPC2/SLIT2/HCLS1/MTOR/CLASP1/DLC1/KANK3/PFN1/CDC42EP5/CORO1A/ARHGEF15/LIMCH1/MAGEL2/SHANK3	59
BP	GO:0001818	negative regulation of cytokine production	65/2486	296/18670	2.639e-05	0.001467	0.00115	ORM1/INPP5D/MMP8/TNFAIP3/ARG2/YY1/C5orf30/NAV3/ARG1/INHBA/PGLYRP1/ADCY7/TNF/TWIST1/SMAD7/LTF/GHRL/TGFB2/LILRA4/TGFB1/ELANE/ZFP36/GAS6/ITCH/GPATCH3/FCGR2B/CX3CL1/CD83/TWSG1/MIR21/ZC3H12A/FN1/BTK/REL/PTGER4/IL23R/IFIH1/CYLD/PML/IGF1/CEACAM1/PDCD1LG2/IL12A/RNF216/KLF4/CD34/LAPTM4B/ACP5/OTUD7B/IL33/TREM2/GPNMB/SSC5D/RNF125/TLR9/HSP90AB1/AKAP8/PCBP2/RPS6KA5/PTPRC/NR1H4/AXL/SYT11/PIN1/NLRP7	65
BP	GO:0003414	chondrocyte morphogenesis involved in endochondral bone morphogenesis	10/2486	18/18670	2.711e-05	0.001467	0.00115	COCH/COL6A1/SCARA3/COL14A1/MATN2/VIT/COL12A1/COL21A1/VWA1/COL6A2	10
BP	GO:0003429	growth plate cartilage chondrocyte morphogenesis	10/2486	18/18670	2.711e-05	0.001467	0.00115	COCH/COL6A1/SCARA3/COL14A1/MATN2/VIT/COL12A1/COL21A1/VWA1/COL6A2	10
BP	GO:0090171	chondrocyte morphogenesis	10/2486	18/18670	2.711e-05	0.001467	0.00115	COCH/COL6A1/SCARA3/COL14A1/MATN2/VIT/COL12A1/COL21A1/VWA1/COL6A2	10
BP	GO:0034504	protein localization to nucleus	59/2486	262/18670	2.828e-05	0.001518	0.00119	FAM53B/MBTPS1/RBM22/NFKBIA/NXT1/NUP93/IPO9/TGFB1/PHB2/HEATR3/RASSF5/IPO7/NOLC1/FLCN/PARP9/ZC3H12A/ZBTB7A/FBXO4/NUP50/KPNA1/SESN2/JUP/PML/CARD10/NUP153/SIX1/KPNA3/NUP188/TAF3/NUP54/TMEM98/NUP214/SMO/GLIS2/BANP/CCT8/NUP155/RPAIN/PLK1/SOX9/DTX3L/DCLK1/GLI3/OTUD7B/RANGAP1/TNPO3/IPO5/FLNA/MSX1/BYSL/DCLK3/SIX2/HCLS1/KPNA4/BARD1/SUN2/SIN3A/LZTS2/PIN1	59
BP	GO:0061572	actin filament bundle organization	40/2486	157/18670	3.009e-05	0.001601	0.001255	EPS8/AIF1L/ITGB5/ARHGAP6/BAG4/WASF2/HSP90B1/TPM1/RND2/NRP1/RHOF/CLASP2/ASAP3/CX3CL1/MIR21/RAPGEF3/PTGER4/ELN/RND3/PHLDB2/DPYSL3/ARHGAP28/RND1/ACTN1/NEDD9/SFRP1/SORBS1/NOX4/PPM1F/FAM107A/FLNA/MTOR/CLASP1/DLC1/TNFAIP1/PFN1/FHDC1/ARHGEF15/LIMCH1/SHANK3	40
BP	GO:0007045	cell-substrate adherens junction assembly	25/2486	81/18670	3.19e-05	0.001663	0.001303	TRIP6/CTTN/ARHGAP6/PDPK1/LDB1/NRP1/CLASP2/COL16A1/ARHGEF7/PHLDB2/FERMT2/WHAMM/ACTN1/TEK/SFRP1/SORBS1/THY1/LIMS1/PPM1F/FAM107A/CLASP1/DLC1/KDR/ITGA2/LIMCH1	25
BP	GO:0048041	focal adhesion assembly	25/2486	81/18670	3.19e-05	0.001663	0.001303	TRIP6/CTTN/ARHGAP6/PDPK1/LDB1/NRP1/CLASP2/COL16A1/ARHGEF7/PHLDB2/FERMT2/WHAMM/ACTN1/TEK/SFRP1/SORBS1/THY1/LIMS1/PPM1F/FAM107A/CLASP1/DLC1/KDR/ITGA2/LIMCH1	25
BP	GO:1903034	regulation of response to wounding	44/2486	179/18670	3.206e-05	0.001663	0.001303	PROS1/SH2B3/SYTL4/TNFAIP3/RGMA/PROC/CD9/CD109/DUSP10/RTN4RL1/PRDX2/SELP/CLASP2/ADRA2A/STK24/MIR21/SPP1/SERPING1/NOS3/WFDC1/SMOC2/PDPN/PTN/TFPI/PTPRF/PDGFRA/CEACAM1/PHLDB2/PLAT/LRIG2/C1QTNF1/KLF4/CD34/MYH9/FKBP1B/FAP/RREB1/CAV1/INPP5F/MTOR/LYN/CLASP1/GP1BA/ABAT	44
BP	GO:0048872	homeostasis of number of cells	56/2486	246/18670	3.237e-05	0.001665	0.001305	ALAS2/KLF13/PMAIP1/SH2B3/EPB42/INPP5D/POLB/TNFAIP3/FADD/SLC4A1/INHBA/PPP2R3C/GATA1/CSF1/LIPA/L3MBTL3/TRIM58/BCL10/IREB2/TGFB1/TAL1/LDB1/PRDX2/AHSP/ZFP36/ARID4A/ZBTB7A/PDE4B/SP3/CYLD/NOS3/P2RX7/ACVR2A/SKIL/JMJD6/CXCL6/MIR17HG/PIK3CD/IL2/SMO/SOX9/NOTCH1/GAPT/PPP3CB/HCLS1/LYN/BAK1/KLF1/TSC22D3/RC3H1/SOX6/CORO1A/DOCK11/AXL/HSPA9/RASSF2	56
BP	GO:0060560	developmental growth involved in morphogenesis	54/2486	235/18670	3.38e-05	0.001725	0.001352	NRCAM/SPRY2/CTTN/FGF13/ITGA4/SEMA3B/BDNF/RNF6/PLXNA3/CSF1/BCL11A/EIF2AK4/TGFB1/RND2/SEMA3G/SPRY1/NRP1/L1CAM/RAPH1/HSP90AA1/FN1/SPP1/SFRP2/SEMA4D/ULK2/CXCL12/SEMA6D/SEMA5B/ITSN2/SIX1/NIN/MAP2/WASF1/SOX9/TBX2/NOTCH1/DCLK1/YAP1/PLXNA1/SFRP1/PPP3CB/CDK5R1/WNT5A/NDN/MAGI2/HSP90AB1/SLIT2/POSTN/SEMA3E/SLIT1/TNC/SIN3A/LZTS2/GDI1	54
BP	GO:0007265	Ras protein signal transduction	90/2486	448/18670	3.479e-05	0.001761	0.00138	RAB28/RHOBTB1/SPRY2/EPS8/IQGAP3/RASSF1/ARHGAP6/RTKN/SCAI/MAPK11/CSF1/WASF2/RAB13/SQSTM1/ARHGEF37/ARFGEF2/JUN/RAB37/TGFB2/CRKL/LPAR6/RND2/SPRY1/KANK2/PHACTR4/PSD3/CTNNAL1/AKAP13/NRP1/RHOF/ADRA2A/FLCN/RAF1/RAPGEF3/G3BP2/USP28/GPR4/ARHGEF7/FGD5/VAV1/LPAR4/SPRY4/GPR35/IGF1/PDPN/ITGA3/PLEKHG5/RAB36/ITSN2/RND3/RHOJ/CBL/IRS2/AGTR1/RND1/WASF1/FARP1/RAB7B/PDGFRB/RIT1/NOTCH1/NOTCH2/RAB12/ARHGAP29/RAB6B/ARHGEF16/DENND4B/NCKAP1/VAV3/RREB1/FGD3/P2RY8/SOS2/MAPKAPK5/MADD/LYN/DLC1/TNFAIP1/RAB8A/MAPKAP1/CDC42EP5/ARHGEF12/RERG/EPHB2/ARHGEF15/FBXO8/KIF14/EPS8L1/GDI1/COL1A2	90
BP	GO:1902903	regulation of supramolecular fiber organization	74/2486	352/18670	3.637e-05	0.001826	0.001431	CLU/RHOBTB1/CTTN/ARHGAP18/EPS8/CIT/FGF13/ARHGAP6/TMOD1/BAG4/MYADM/NAV3/ARF1/CLIP3/APC/WASF2/SNCA/DLG1/TPM1/FKBP4/AKAP13/NRP1/CLASP2/ASAP3/CX3CL1/MIR21/RAPGEF3/PTGER4/ELN/AVIL/CXCL12/COTL1/AP1AR/PHLDB2/NIN/MAP2/PFN4/TTBK2/LMOD1/ARHGAP28/PLEKHH2/MID1/WHAMM/WASF1/MYO1C/CAPZA1/TMSB4Y/FCHSD2/CCL21/SFRP1/CDK5R1/NCKAP1/TMSB15A/NOX4/PPM1F/PAK3/MIR214/FLNA/ARPC2/CDH5/SLIT2/HCLS1/MTOR/CLASP1/DLC1/KANK3/PFN1/CDC42EP5/CRYAB/CORO1A/ARHGEF15/LIMCH1/MAGEL2/SHANK3	74
BP	GO:1905330	regulation of morphogenesis of an epithelium	44/2486	180/18670	3.704e-05	0.001845	0.001446	PSMD14/PSMD12/TNF/PLEKHA4/TGFB1/PSMD7/PSMB5/PHB2/CLASP2/MIR21/GPC4/DAB2/AP2A2/SFRP2/SIX1/HOXB7/GPC6/PHLDB2/SULF1/SEC24B/SMO/RSPO3/PSMB7/SOX9/TBX2/CTHRC1/PSMD1/SFRP1/PSMD9/FZD5/RREB1/WNT5A/ROR1/MAGI2/PARD6A/SIX2/NTN4/MTOR/CLASP1/FZD4/PSME1/PFN1/ADAMTS12/PRICKLE2	44
BP	GO:0030199	collagen fibril organization	19/2486	54/18670	3.743e-05	0.001849	0.001449	ADAMTS2/PLOD2/TGFB2/TNXB/PXDN/FOXC1/LOX/SFRP2/SERPINH1/ADAMTS14/COL14A1/DPT/COL5A1/COL12A1/ACAN/DDR2/FMOD/COL5A2/COL1A2	19
BP	GO:0051494	negative regulation of cytoskeleton organization	38/2486	148/18670	3.914e-05	0.001918	0.001504	RBM14/EPS8/FGF13/ARHGAP6/TMOD1/MYADM/NAV3/CLIP3/APC/WASF2/SNCA/FKBP4/CLASP2/MIR21/MDM1/AVIL/PHLDB2/MAP2/PFN4/TTBK2/LMOD1/ARHGAP28/PLEKHH2/MID1/CAPZA1/TMSB4Y/TMSB15A/MIR214/CDH5/SLIT2/CLASP1/DLC1/TMEM67/KANK3/PFN1/CORO1A/NEK2/SHANK3	38
BP	GO:0045765	regulation of angiogenesis	79/2486	383/18670	4.038e-05	0.001964	0.001539	ANXA3/SPRY2/CHI3L1/DDAH1/PDPK1/TNFAIP3/PPARG/SPARC/GTF2I/PRKCB/TWIST1/FLT1/GHRL/TGFB2/VEGFC/HIPK1/NRP1/FBXW7/CX3CL1/MIR21/SMAD1/ZC3H12A/FOXC1/FGF18/RAPGEF3/GPR4/ANGPTL4/MMRN2/SIRT1/THBS4/JUP/ECM1/NOS3/JAK1/ECSCR/HSPB1/SFRP2/PML/SMOC2/ADAMTS9/CARD10/VASH1/PTN/RAMP2/RHOJ/COL4A2/PAK4/CEACAM1/SRPX2/AGTR1/SULF1/AQP1/MEOX2/KLF4/APLNR/EMP2/CREB3L1/TIE1/CD34/NOTCH1/IL1B/TEK/SFRP1/HSPB6/ANGPT2/ENPP2/GPNMB/PDCD10/ITGB8/WNT5A/MIR214/DCN/CDH5/MAP3K3/KDR/SEMA3E/FOXJ2/HYAL1/CCBE1	79
BP	GO:0010171	body morphogenesis	18/2486	50/18670	4.197e-05	0.002025	0.001587	CLDN5/EP300/NIPBL/TGFB1/CLASP2/TIPARP/ASPH/PDGFRA/CSRNP1/PHLDB2/CDON/GREM2/ZNF281/MAB21L2/MSX1/TBX1/SSBP3/CLASP1	18
BP	GO:0050808	synapse organization	83/2486	408/18670	4.367e-05	0.002063	0.001617	C1QB/C1QA/NRCAM/CTTN/C1QC/PTPRO/SPARC/ARF1/WASF3/BDNF/WASF2/CACNA2D2/SNCA/TNF/DLG1/GHRL/CRKL/CUX2/SSH1/AGRN/CTTNBP2/CACNB3/NRP1/L1CAM/FCGR2B/CX3CL1/NEFH/DLG2/IGF1R/GPC4/TPBG/NFATC4/NTRK2/LRRN1/SEMA4D/ITGA3/YWHAZ/PTN/VCP/SIX1/FLRT2/COL4A1/UTRN/PTPRF/SDK1/CRIPT/SRPX2/PCDHB14/EFNB2/ACTN1/WASF1/POU4F1/FARP1/GAP43/SPARCL1/PCDH17/PDZRN3/TREM2/FZD5/CDK5R1/OXTR/REST/WNT5A/PAK3/MAGI2/IGSF9/PCDHGC5/NLGN4X/IL10RA/IGSF21/MYH10/SEMA3E/ARC/GLRB/SLIT1/PFN1/UNC13B/TNC/STAU1/EPHB2/ARHGEF15/SHANK3/PIN1	83
BP	GO:0050817	coagulation	72/2486	342/18670	4.387e-05	0.002063	0.001617	HBB/PROS1/ITGB3/HBD/MYL9/SH2B3/PDPK1/ITPR1/CD177/PEAR1/PABPC4/SLC4A1/GATA1/PROC/PRKCB/PRKAR2A/CD9/IRF1/CD59/CYP4F2/PRDX2/SELP/VWF/GAS6/STXBP1/ADRA2A/RAF1/P2RY12/EHD2/SERPING1/NOS3/VAV1/HSPB1/TREML1/P2RX7/MMRN1/F8/PDPN/YWHAZ/F13A1/TFPI/PDGFRA/CEACAM1/DGKD/PLAT/C1QTNF1/CAPZA1/CD34/JMJD1C/MYH9/FAP/ZFPM2/VAV3/FBLN1/PHF21A/FLNA/GNA14/CAV1/DGKZ/LYN/METAP1/ITGA2/CSRP1/GP1BA/A2M/PRKAR2B/DOCK11/DOCK8/AXL/C1GALT1C1/ABAT/COL1A2	72
BP	GO:0002683	negative regulation of immune system process	92/2486	463/18670	4.405e-05	0.002063	0.001617	LPXN/KLF13/C1QC/PDPK1/INPP5D/TNFAIP3/ARG2/OTUD4/FADD/PPARG/PARP3/HTRA1/ARG1/INHBA/NFKBIA/PGLYRP1/IRF1/TNF/SMAD7/DLG1/YTHDF2/HOXA7/DUSP10/BCL10/LTF/TGFB2/CD59/LILRA4/TGFB1/TAL1/LDB1/PRDX2/ZFP36/IFI16/HES1/SAMHD1/RHBDD3/ITCH/GPATCH3/FBXW7/FCGR2B/TAPBPL/CX3CL1/TWSG1/MIR21/ZC3H12A/IRF4/HLX/BTK/PTGER4/SERPING1/MEIS2/CXCL12/TSPAN6/PLCB1/CEACAM1/IL13RA2/PDCD1LG2/IL2/SERPINB9/RAB7B/SOX9/TNFRSF14/NOTCH1/GLI3/CD300LF/IL17D/CCL21/SFRP1/IL33/THY1/PPP3CB/GPNMB/RNF125/YTHDF3/TLR9/DUSP1/CD300A/CNOT7/SLIT2/LYN/HOXA9/ADCYAP1/SPN/FBN1/PCBP2/A2M/TSC22D3/RC3H1/PTPRC/AXL/HSPA9	92
BP	GO:0090130	tissue migration	75/2486	360/18670	4.435e-05	0.002063	0.001617	ITGB3/ANXA3/PDPK1/PPARG/SPARC/RAB13/JUN/DUSP10/TGFB2/VEGFC/TGFB1/ACTG2/PTP4A3/ANLN/KANK2/NRP1/CLASP2/FBXW7/MIR21/ZC3H12A/FGF18/CAPN7/MMRN2/SIRT1/JUP/NOS3/HSPB1/STC1/SMOC2/ADAMTS9/ITGA3/PLEKHG5/CARD10/VASH1/PTN/EPHB4/RHOJ/CEACAM1/MMP9/NR2F2/DNAJA4/SRPX2/EFNB2/MEOX2/BCAR1/KLF4/EMP2/HAS2/SOX9/NOTCH1/CLEC14A/MYH9/TEK/PTPRG/FAP/ANGPT2/PKN3/ENPP2/PDCD10/PKN2/PPM1F/RREB1/WNT5A/DCN/MAP3K3/SLIT2/MTOR/CLASP1/KDR/ITGA2/ACTA2/PFN1/GIPC1/HYAL1/CCBE1	75
BP	GO:0018212	peptidyl-tyrosine modification	76/2486	366/18670	4.442e-05	0.002063	0.001617	ITGB3/DSTYK/ACVR1/SH2B3/BMX/NTF3/SH3BP5L/TPST1/GATA1/BDNF/CLK1/TNF/FLT1/PPP2CA/GHRL/UNC119/TGFB1/TAL1/HES1/NRP1/GAS6/CRLF1/ACE/FBXW7/ADRA2A/PARP9/IGF1R/CHMP6/BTK/TPST2/THBS4/EGFR/NTRK2/IL23R/JAK1/SFRP2/SEMA4D/IGF1/EGF/EPHB4/PDGFRA/CBL/IL12A/MELK/IL2/CLK3/PDGFRB/AFAP1L2/TNFRSF14/TIE1/TEK/IBTK/NEDD9/SFRP1/THY1/TREM2/ENPP2/NOX4/EFEMP1/ROR1/CD300A/CNOT7/DDR2/PKDCC/CAV1/HCLS1/CSPG4/TTK/INPP5F/MTOR/LYN/GHR/KDR/EPHB2/PTPRC/AXL	76
BP	GO:0002573	myeloid leukocyte differentiation	48/2486	204/18670	4.802e-05	0.002214	0.001735	C1QC/INPP5D/FADD/PPARG/INHBA/GATA1/CSF1/L3MBTL3/TNF/JUN/CD109/HOXA7/LTF/IREB2/TGFB1/TAL1/CREB1/IFI16/FBXW7/BATF2/IRF4/FOS/CEBPE/SIRT1/JAGN1/SP3/TRAF6/IL23R/BATF/CBFA2T3/PIR/TNFRSF11A/CEACAM1/MMP9/KLF10/PIK3CD/POU4F1/NOTCH2/MYH9/SFRP1/TREM2/HCLS1/MTOR/LYN/BATF3/FBN1/JUNB/RASSF2	48
BP	GO:0048732	gland development	87/2486	434/18670	5.057e-05	0.002289	0.001794	LRP5L/IQGAP3/CIT/SLC9A3R1/POLB/TNFAIP3/FADD/ARG1/CSF1/ATP7B/PBX1/TAF10/TNF/JUN/LIMS2/TGFB2/CRKL/CDO1/TGFB1/FKBP4/PHB2/PRDX2/CREB1/HES1/CDKN1C/NRP1/RHBDD3/FBXW7/CCND1/TWSG1/SMARCC1/RAF1/PAM/THRB/FOXC1/BMP2/HLX/NFIB/SP3/EGFR/PML/RELA/MSN/EGF/PTN/ASS1/SIX1/PDGFRA/TNFRSF11A/CEACAM1/IRS2/IGFBP5/SULF1/SMO/FRS2/SOX9/TBX2/NOTCH1/JARID2/ALDH1A3/GLI3/PLXNA1/CPS1/SFRP1/ALDH1A2/OXTR/RREB1/WNT5A/MSX1/HMGCS1/TBX1/CAV1/NTN4/HOXA9/MAN2A1/ADCYAP1/ITGA2/MST1/E2F8/TNC/MGMT/DKK3/HOXA3/LRP5/HOXD9/HMGCL/NCOA1	87
BP	GO:0009612	response to mechanical stimulus	49/2486	210/18670	5.059e-05	0.002289	0.001794	CHI3L1/CRADD/JUND/FOSB/FADD/PPARG/NFKBIA/IRF1/JUN/BCL10/SLC1A3/TGFB1/IGFBP2/PKD2L2/PDE2A/CACNB3/MAP3K14/RAF1/FOS/PTGER4/JUP/MAP3K2/EGFR/MEIS2/P2RX7/MAP3K1/RELA/CXCL12/PTN/LRP11/KCNA5/TMEM150C/AQP1/SOX9/KCNA1/IL1B/BTG2/ANGPT2/DCN/RYR2/PKD1L2/POSTN/BAK1/ITGA2/DMD/TNC/JUNB/ETV1/SHANK3	49
BP	GO:0002831	regulation of response to biotic stimulus	36/2486	139/18670	5.075e-05	0.002289	0.001794	SIRT2/TNFAIP3/ARG2/HTRA1/ARG1/PPP2R3C/TRIM6/EIF2AK4/LTF/DHX9/PRDX2/ITCH/FBXO38/GPATCH3/CX3CL1/PARP9/ZC3H12A/TRAF6/PQBP1/IL23R/TSPAN6/CXCL6/CEACAM1/IL12A/IFIT1/RNF216/LRSAM1/DTX3L/IL1B/RNF125/PCBP2/UNC13B/SIN3A/SYT11/ZCCHC3/TRIM44	36
BP	GO:0019083	viral transcription	43/2486	177/18670	5.275e-05	0.002362	0.001851	RPS27/RPS28/EP300/JUN/NUP93/DHX9/IFITM3/CDK9/RPS15/TRIM21/ZFP36/UBA52/RPS26/RPLP1/CHD1/RPL28/RPS3A/NUP50/RPL10/CCNT2/RPL29/POLR2G/NUP153/NUP210/RAE1/NUP188/RPS8/RPS4Y1/NUP160/RSF1/RPS2/NUP54/RPL39/RPS10/NUP214/NUP155/RPL6/REST/RPL14/RPS7/POLR2D/RPL9/RPL15	43
BP	GO:0008360	regulation of cell shape	38/2486	150/18670	5.368e-05	0.00238	0.001865	ARHGAP18/EPS8/COCH/EPB42/SLC9A3R1/WASF3/PLXNA3/DLG1/FBLIM1/TPM1/RND2/FMNL1/RHOF/ITGA7/DIAPH1/MIR21/FN1/CCL13/FGD5/SEMA4D/PDPN/MSN/PTN/RND3/RHOJ/FERMT2/RND1/MYH9/PLXNA1/FGD3/PALMD/DLC1/KDR/MYH10/SEMA3E/CDC42EP5/CORO1A/PARVA	38
BP	GO:0048048	embryonic eye morphogenesis	14/2486	34/18670	5.391e-05	0.00238	0.001865	ARID1A/TWIST1/PHACTR4/HIPK1/FBN2/SP3/FRS2/MFAP2/TBX2/ALDH1A3/FZD5/WNT5A/EFEMP1/FBN1	14
BP	GO:0031668	cellular response to extracellular stimulus	59/2486	268/18670	5.635e-05	0.00247	0.001936	RRAGA/PMAIP1/GABARAPL2/NUDT15/MAP1LC3A/PPARG/ITGA4/KIF26A/DEPDC5/BCL11A/HSP90B1/EIF2AK4/JUN/LPL/SSH1/LCN2/PPM1D/KANK2/IFI16/CACNB3/GAS6/EIF2S1/STK24/P2RY12/ZC3H12A/FOS/SIRT1/SESN2/PHEX/MAX/TRIM24/SFRP2/P2RX7/TBL2/MAP3K5/CADPS2/PTN/CBL/P2RY2/KLF10/SESN3/CIB2/SFRP1/CDKN2B/SKP2/FAM107A/USP33/NR4A2/MTOR/LYN/POSTN/TAF1/HSPA5/PDK4/TNC/PTPRC/NR1H4/AXL/NCOA1	59
BP	GO:0007043	cell-cell junction assembly	33/2486	124/18670	5.755e-05	0.002505	0.001964	CLDN5/PTPRO/MPP5/APC/PARD3/RAB13/CD9/TNF/PARD6G/DLG1/ESAM/ACE/GJA5/FLCN/GJA4/JUP/CDH26/RAMP2/NPHP1/PKP4/MYO1C/MPP7/FZD5/ANK2/PKN2/TJP1/PARD6A/CDH5/CAV1/CDH6/NR1H4/PARD6B/CDH11	33
BP	GO:0010631	epithelial cell migration	73/2486	351/18670	5.899e-05	0.00255	0.001999	ITGB3/ANXA3/PDPK1/PPARG/SPARC/RAB13/JUN/DUSP10/TGFB2/VEGFC/TGFB1/PTP4A3/ANLN/KANK2/NRP1/CLASP2/FBXW7/MIR21/ZC3H12A/FGF18/CAPN7/MMRN2/SIRT1/JUP/NOS3/HSPB1/STC1/SMOC2/ADAMTS9/ITGA3/PLEKHG5/CARD10/VASH1/PTN/EPHB4/RHOJ/CEACAM1/MMP9/NR2F2/DNAJA4/SRPX2/EFNB2/MEOX2/BCAR1/KLF4/EMP2/HAS2/SOX9/NOTCH1/CLEC14A/MYH9/TEK/PTPRG/FAP/ANGPT2/PKN3/ENPP2/PDCD10/PKN2/PPM1F/RREB1/WNT5A/DCN/MAP3K3/SLIT2/MTOR/CLASP1/KDR/ITGA2/PFN1/GIPC1/HYAL1/CCBE1	73
BP	GO:0001570	vasculogenesis	24/2486	79/18670	6.056e-05	0.0026	0.002038	TBX5/TGFB1/TIPARP/FBXW7/EGFL7/NTRK2/RAMP2/CEACAM1/SMO/APLNR/EMP2/PDGFRB/HAS2/TIE1/CD34/NOTCH1/YAP1/ZFPM2/ITGB8/CAV1/KDR/FZD4/JUNB/SETD2	24
BP	GO:0098868	bone growth	17/2486	47/18670	6.364e-05	0.002713	0.002127	COCH/COL6A1/EVC/SMPD3/SCARA3/ECM1/STC1/COL27A1/COL14A1/THBS3/MATN2/VIT/COL12A1/COL21A1/DDR2/VWA1/COL6A2	17
BP	GO:0007494	midgut development	8/2486	13/18670	6.736e-05	0.002853	0.002236	EDNRB/EGFR/ASS1/SMO/CPS1/ALDH1A2/FOXL1/WNT5A	8
BP	GO:0030326	embryonic limb morphogenesis	33/2486	125/18670	6.834e-05	0.002855	0.002238	MBNL1/NIPBL/TBX5/PBX1/TWIST1/TGFB2/B9D1/PBX2/CYP26B1/GJA5/CREBBP/WDR19/FBN2/LMBR1/SFRP2/HOXC10/WNT9A/HOXA10/PRRX1/IFT140/TBX2/NOTCH1/SHOX2/GLI3/HOXA11/C2CD3/ALDH1A2/WNT5A/MSX1/HOXA9/INTU/TMEM231/HOXD9	33
BP	GO:0035113	embryonic appendage morphogenesis	33/2486	125/18670	6.834e-05	0.002855	0.002238	MBNL1/NIPBL/TBX5/PBX1/TWIST1/TGFB2/B9D1/PBX2/CYP26B1/GJA5/CREBBP/WDR19/FBN2/LMBR1/SFRP2/HOXC10/WNT9A/HOXA10/PRRX1/IFT140/TBX2/NOTCH1/SHOX2/GLI3/HOXA11/C2CD3/ALDH1A2/WNT5A/MSX1/HOXA9/INTU/TMEM231/HOXD9	33
BP	GO:0045165	cell fate commitment	59/2486	270/18670	7.031e-05	0.002918	0.002287	SPRY2/ACVR1/FGF13/PPARG/GATA1/APC/TBX5/GAS1/WNT5B/TAL1/KDM6B/HES1/NRP1/CYP26B1/JAG2/NANOG/SMAD1/IRF4/BMP2/IL23R/CYLD/BATF/SFRP2/DMRT3/PML/PDPN/HOXC10/SATB2/SIX1/TGFB1I1/WNT9A/NR2F2/CDON/SMO/PRRX1/POU4F1/KLF4/MCL1/GAP43/SOX9/TBX2/NOTCH1/NOTCH2/GLI3/HOXA11/SFRP1/TBX15/FKBP8/TBX22/WNT5A/TBX1/CHD5/EBF2/SIX2/MTOR/OLIG1/SPN/SOX6/NOTCH3	59
BP	GO:0001763	morphogenesis of a branching structure	46/2486	196/18670	7.289e-05	0.002985	0.00234	LRP5L/SPRY2/ACVR1/CSF1/BCL11A/PBX1/TNF/DLG1/TGFB1/PHB2/SPRY1/NRP1/BMP2/NFATC4/SFRP2/PML/NPNT/EGF/SIX1/COL4A1/HOXB7/STK4/SULF1/SMO/RSPO3/FRS2/SOX9/NOTCH1/SHOX2/YAP1/GLI3/HOXA11/PLXNA1/SFRP1/FZD5/WNT5A/ADAMTS16/SIX2/SLIT2/NTN4/GZF1/SEMA3E/TNC/SPINT2/LRP5/SETD2	46
BP	GO:0002685	regulation of leukocyte migration	46/2486	196/18670	7.289e-05	0.002985	0.00234	FADD/ITGA4/CSF1/CD9/TNF/HOXA7/CRKL/VEGFC/IL1R1/AKIRIN1/TGFB1/ELANE/SELP/GAS6/SMPD3/P2RY12/PLVAP/PTGER4/EDN3/THBS4/ECM1/RARRES2/CXCL12/DAPK2/MTUS1/MSN/PTN/PLCB1/STK10/IL12A/TNFRSF14/CCL21/IL33/THY1/TREM2/WNT5A/CCL8/DUSP1/CD300A/SLIT2/LYN/SPN/ITGA2/MST1/XG/DOCK8	46
BP	GO:0007369	gastrulation	44/2486	185/18670	7.434e-05	0.003024	0.00237	ITGB3/LRP5L/ARID1A/ACVR1/ITGB5/MMP8/MBP/ITGA4/MYADM/INHBA/COL6A1/SYF2/TAL1/LDB1/KDM6B/CLASP2/ITGA7/TWSG1/NANOG/SMAD1/FN1/FOXC1/SFRP2/ACVR2A/TGIF2/ITGA3/COL4A2/PHLDB2/MMP9/FRS2/KLF4/APLNR/COL5A1/HOXA11/SFRP1/LAMB1/COL12A1/WNT5A/SIX2/CLASP1/ITGA2/COL5A2/LRP5/SETD2	44
BP	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	20/2486	61/18670	7.481e-05	0.003024	0.00237	PMAIP1/BCLAF1/SLC9A3R1/SFPQ/FBXW7/FLCN/RNF183/SIRT1/DDIT3/BCL2L1/SKIL/SERINC3/BMF/MCL1/NUPR1/PLAGL2/MSX1/CAV1/RPS7/STYXL1	20
BP	GO:2000677	regulation of transcription regulatory region DNA binding	18/2486	52/18670	7.621e-05	0.00305	0.002391	SRI/EP300/GATA1/TRIM6/TWIST1/TGFB1/FBXW7/FOXC1/ZBTB7A/DDIT3/TRAF6/IGF1/POU4F1/KLF4/NSD1/MSX1/TAF1/SIN3A	18
BP	GO:0050678	regulation of epithelial cell proliferation	77/2486	378/18670	7.746e-05	0.00305	0.002391	ITGB3/IQGAP3/PDPK1/TNFAIP3/EDNRB/PPARG/ITGA4/HTRA1/SPARC/ARG1/CAV2/TNF/TWIST1/FLT1/JUN/LIMS2/CD109/DLG1/DUSP10/GHRL/TGFB2/VEGFC/LAMC1/TGFB1/PHB2/ZFP36/HES1/CDKN1C/NRP1/FBXW7/CCND1/MIR21/BMP2/EGFL7/NFIB/SIRT1/THBS4/EGFR/ECM1/SFRP2/WFDC1/MTSS1/IGF1/CXCL12/VASH1/PTN/SIX1/CEACAM1/NR2F2/AGTR1/SULF1/EFNB2/SMO/FRS2/APLNR/HAS2/NUPR1/SOX9/NOTCH1/NOTCH2/YAP1/TEK/SFRP1/ALDH1A2/CDKN2B/LAMB1/PDCD10/RREB1/WNT5A/IL26/TBX1/CAV1/MTOR/KDR/INTU/MST1/HYAL1	77
BP	GO:0032496	response to lipopolysaccharide	69/2486	330/18670	7.814e-05	0.00305	0.002391	SLPI/CXCL5/JUND/TNFAIP3/EDNRB/CTSG/NFKBIB/IRF8/SPARC/ARG1/NFKB2/NFKBIA/TRIM6/SNCA/HPGD/TNF/JUN/DUSP10/BCL10/LTF/TGFB1/ELANE/LCN2/PRDX2/SELP/ZFP36/CX3CL1/MIR21/ZC3H12A/ALPL/PDE4B/FOS/PTGER4/CEBPE/TRAF6/GCH1/IL23R/NOS3/P2RX7/RELA/PLSCR4/LIAS/ASS1/PABPN1/PTGFR/CXCL6/LOXL1/TFPI/TNFRSF11A/GJB6/PDCD1LG2/IL12A/NOTCH1/ACP5/IL1B/CPS1/TREM2/TIMP4/CXCL1/WNT5A/DCN/GNG12/AKAP8/IL10RA/LYN/JUNB/NR1H4/AXL/NLRP7	69
BP	GO:0090132	epithelium migration	73/2486	354/18670	7.843e-05	0.00305	0.002391	ITGB3/ANXA3/PDPK1/PPARG/SPARC/RAB13/JUN/DUSP10/TGFB2/VEGFC/TGFB1/PTP4A3/ANLN/KANK2/NRP1/CLASP2/FBXW7/MIR21/ZC3H12A/FGF18/CAPN7/MMRN2/SIRT1/JUP/NOS3/HSPB1/STC1/SMOC2/ADAMTS9/ITGA3/PLEKHG5/CARD10/VASH1/PTN/EPHB4/RHOJ/CEACAM1/MMP9/NR2F2/DNAJA4/SRPX2/EFNB2/MEOX2/BCAR1/KLF4/EMP2/HAS2/SOX9/NOTCH1/CLEC14A/MYH9/TEK/PTPRG/FAP/ANGPT2/PKN3/ENPP2/PDCD10/PKN2/PPM1F/RREB1/WNT5A/DCN/MAP3K3/SLIT2/MTOR/CLASP1/KDR/ITGA2/PFN1/GIPC1/HYAL1/CCBE1	73
BP	GO:1903035	negative regulation of response to wounding	26/2486	90/18670	7.857e-05	0.00305	0.002391	PROS1/SH2B3/RGMA/PROC/CD9/CD109/DUSP10/RTN4RL1/CLASP2/SPP1/SERPING1/NOS3/WFDC1/TFPI/PDGFRA/CEACAM1/PHLDB2/PLAT/LRIG2/C1QTNF1/CD34/FAP/INPP5F/CLASP1/GP1BA/ABAT	26
BP	GO:0110111	negative regulation of animal organ morphogenesis	14/2486	35/18670	7.889e-05	0.00305	0.002391	BCOR/TNF/LIMS2/TGFB2/FBXW7/THRB/FOXC1/NFIB/CEACAM1/SULF1/TBX2/NOTCH1/ASPN/WNT5A	14
BP	GO:1990774	tumor necrosis factor secretion	14/2486	35/18670	7.889e-05	0.00305	0.002391	ORM1/MMP8/ARG2/LPL/GHRL/DHX9/CX3CL1/ZC3H12A/IFIH1/FZD5/WNT5A/FRMD8/NR1H4/SYT11	14
BP	GO:0002697	regulation of immune effector process	90/2486	458/18670	8.072e-05	0.003095	0.002426	CLU/PROS1/FAM49B/C1QB/C1QA/CD1C/C1QC/PDPK1/CR1L/TNFAIP3/CD177/CFH/FADD/PARP3/HTRA1/ARG1/TRIM6/EIF2AK4/PGLYRP1/TNF/SMAD7/DUSP10/BCL10/TGFB2/CD59/IL1R1/DHX9/CD244/TGFB1/C2/CFB/ITCH/FBXO38/GPATCH3/STXBP1/FCGR2B/MIR21/PARP9/ZC3H12A/CD1B/IRF4/NFKBIZ/DDX21/HLX/BTK/SERPING1/EXOSC3/TRAF6/PQBP1/IL23R/VAV1/P2RX7/CFHR2/C12orf4/TSPAN6/CXCL6/CPN1/HLA-B/CEACAM1/IL13RA2/IL12A/IFIT1/IL2/RNF216/C1R/SERPINB9/TNFRSF14/DTX3L/IL1B/STX4/IL33/PPP3CB/FZD5/RNF125/WNT5A/TLR9/CD300A/LYN/C1S/CFI/PCBP2/A2M/RC3H1/TRIL/PTPRC/RSAD2/SIN3A/HLA-A/ZCCHC3/TRIM44	90
BP	GO:0045088	regulation of innate immune response	89/2486	452/18670	8.186e-05	0.003095	0.002426	MUC1/RBM14/PSMD14/PSMD12/COCH/CLEC4C/PDPK1/TNFAIP3/XRCC6/OTUD4/FADD/PPARG/ARG1/EP300/NFKBIA/TRIM6/HSP90B1/PGLYRP1/IRF1/YTHDF2/DUSP10/BCL10/LTF/SFPQ/LILRA4/DHX9/PSMD7/PSMB5/IFI16/SAMHD1/UBA52/ITCH/TNIP1/GPATCH3/FCGR2B/MIR21/MATR3/CREBBP/PARP9/RAF1/IRF4/BTK/SERPING1/TRAF6/PQBP1/IFIH1/CYLD/VAV1/JAK1/MAP3K1/RELA/TSPAN6/CEACAM1/IL12A/PSMB7/SERPINB9/RAB7B/CNPY3/CD300LF/PSMD1/TREM2/MUC2/PSMD9/UBC/UBE2D3/RNF125/COLEC12/WNT5A/PAK3/YTHDF3/TLR9/NONO/CD300A/CNOT7/HSP90AB1/CAV1/LYN/MUC3A/PSME1/A2M/RPS6KA5/TRIL/NR1H4/RSAD2/ABCE1/ALPK1/SIN3A/CUL1/ZCCHC3	89
BP	GO:1902904	negative regulation of supramolecular fiber organization	36/2486	142/18670	8.195e-05	0.003095	0.002426	CLU/EPS8/FGF13/ARHGAP6/TMOD1/MYADM/NAV3/CLIP3/APC/WASF2/SNCA/FKBP4/CLASP2/MIR21/AVIL/PHLDB2/MAP2/PFN4/TTBK2/LMOD1/ARHGAP28/PLEKHH2/MID1/CAPZA1/TMSB4Y/TMSB15A/MIR214/CDH5/SLIT2/CLASP1/DLC1/KANK3/PFN1/CRYAB/CORO1A/SHANK3	36
BP	GO:0007162	negative regulation of cell adhesion	62/2486	289/18670	8.203e-05	0.003095	0.002426	MUC1/LPXN/SH2B3/ARHGAP6/ARG2/PTPRO/MBP/MYADM/ARG1/PLXNA3/CD9/IRF1/SMAD7/DLG1/YTHDF2/HOXA7/TGFB1/PRDX2/CLASP2/FCGR2B/CX3CL1/TWSG1/MIR21/ZC3H12A/BMP2/HLX/JAM2/SEMA4D/CXCL12/ASS1/AP1AR/CEACAM1/PHLDB2/PDCD1LG2/RND1/C1QTNF1/IL2/KLF4/TNFRSF14/NOTCH1/GLI3/PLXNA1/DACT2/CCL21/ANGPT2/GPNMB/PPM1F/FBLN1/FAM107A/PODXL/DUSP1/CD300A/DLC1/POSTN/SPN/FZD4/SEMA3E/TNC/SPINT2/RC3H1/PTPRC/ABAT	62
BP	GO:0031331	positive regulation of cellular catabolic process	74/2486	361/18670	8.589e-05	0.003215	0.00252	CLU/SIRT2/VPS13C/TNFAIP3/KEAP1/EDEM1/CNOT8/EIF2AK4/SNCA/TNF/TWIST1/SMAD7/YTHDF2/PINK1/PFKFB2/TNRC6B/TRIM21/ZFP36/ARIH2/HERPUD1/ITCH/FBXW7/ADRA2A/LARP1/HSP90AA1/FLCN/ZC3H12A/RAB3GAP2/DAB2/SIRT1/SESN2/ECSCR/SMCR8/P2RX7/CBFA2T3/IGF1/POLR2G/ZFAND2A/MSN/FYCO1/EGF/VCP/WAC/CSNK1A1/IRS2/RCHY1/SESN3/PLK3/PLK1/NUPR1/LRSAM1/DTX3L/IL1B/RAB12/BTG2/IL33/TREM2/UVRAG/DCN/YTHDF3/RNF139/RNF19B/CHFR/ARIH1/CNOT7/CAV1/KDR/TAF1/GPSM1/RC3H1/HSPB8/SCOC/SH3D19/CNOT1	74
BP	GO:0043405	regulation of MAP kinase activity	70/2486	337/18670	8.625e-05	0.003215	0.00252	SPRY2/IQGAP3/SH2B3/NTF3/MAPK11/TNF/FLT1/DUSP10/PPP2CA/DNAJA1/GHRL/CRKL/TGFB1/ELANE/PRDX2/SORL1/SPRY1/AKAP13/UBA52/PPEF2/ERN1/ADRA2A/ERP29/MAP3K14/RAF1/IGF1R/FGF18/BMP2/EDN3/TRAF6/MAP3K2/EGFR/SFRP2/P2RX7/SPRY4/UCHL1/SAMD5/MAP3K5/MAP3K1/IGF1/TPD52L1/EGF/TNFRSF11A/FZD10/FRS2/PDGFRB/IL1B/SFRP1/FZD5/UBC/PDCD10/NOX4/WNT5A/PAK3/TLR9/DUSP1/CD300A/CAV1/MAP3K3/MAPKAPK5/CSPG4/MADD/LYN/DUSP18/GHR/RGS14/PDE6G/FZD4/EPHB2/PTPRC	70
BP	GO:0035107	appendage morphogenesis	37/2486	148/18670	9.018e-05	0.003322	0.002603	MBNL1/NIPBL/TBX5/PBX1/TWIST1/TGFB2/B9D1/PBX2/CYP26B1/GJA5/CREBBP/WDR19/FBN2/LMBR1/ASPH/SFRP2/HOXC10/WNT9A/HOXA10/PRRX1/IFT140/SOX9/TBX2/NOTCH1/SHOX2/GLI3/HOXA11/C2CD3/ALDH1A2/WNT5A/MSX1/PKDCC/HOXA9/BAK1/INTU/TMEM231/HOXD9	37
BP	GO:0035108	limb morphogenesis	37/2486	148/18670	9.018e-05	0.003322	0.002603	MBNL1/NIPBL/TBX5/PBX1/TWIST1/TGFB2/B9D1/PBX2/CYP26B1/GJA5/CREBBP/WDR19/FBN2/LMBR1/ASPH/SFRP2/HOXC10/WNT9A/HOXA10/PRRX1/IFT140/SOX9/TBX2/NOTCH1/SHOX2/GLI3/HOXA11/C2CD3/ALDH1A2/WNT5A/MSX1/PKDCC/HOXA9/BAK1/INTU/TMEM231/HOXD9	37
BP	GO:0007492	endoderm development	23/2486	76/18670	9.139e-05	0.00333	0.00261	ITGB5/MMP8/PELO/ITGA4/INHBA/COL6A1/LAMC1/TGFB1/LDB1/ITGA7/NANOG/FN1/COL4A2/MMP9/COL5A1/NOTCH1/LAMB1/BPTF/COL12A1/SSBP3/ARC/COL5A2/SETD2	23
BP	GO:0050708	regulation of protein secretion	92/2486	472/18670	9.197e-05	0.00333	0.00261	SRI/LRP5L/ORM1/SYTL4/MMP8/ITPR1/TNFAIP3/ARG2/MBP/CDK16/ARF1/MAPK11/TRIM6/SLC25A5/CACNA2D2/TNF/TWIST1/LPL/GHRL/TGFB2/FRMD4A/VEGFC/DHX9/CD244/TGFB1/SERP1/TRH/RAB11FIP1/PFKFB2/RAB11FIP5/C2CD2L/GAS6/RHBDD3/ICA1/FCGR2B/ADRA2A/PPID/ERP29/GJA5/CX3CL1/PAM/ZC3H12A/FN1/RAPGEF3/PTGER4/JAGN1/TRAF6/TM7SF3/EGFR/IFIH1/P2RX7/PML/IGF1/SLC25A6/RHBDF1/IRS2/KCNA5/IL2/TNFRSF14/BMP8A/CD34/IL1B/STX4/FKBP1B/SFRP1/IL33/TREM2/PPP3CB/PSMD9/FZD5/SSC5D/NLRP1/REST/WNT5A/TLR9/IL26/PARD6A/CAPN10/LYN/POSTN/KCNS3/FRMD8/MYH10/MIDN/UNC13B/NR1H4/RSAD2/LRP5/RAPGEF4/SYT11/ABAT/NLRP7	92
BP	GO:0071772	response to BMP	41/2486	170/18670	9.254e-05	0.00333	0.00261	ACVR1/PELO/HTRA1/RGMA/HEYL/USP9Y/SMAD7/FSTL1/SORL1/HES1/RBPMS2/PCSK6/TWSG1/MIR21/SMPD3/SMAD1/BMP2/HTRA3/SFRP2/ACVR2A/SKIL/ITGA3/SULF1/SFRP4/PPM1A/GREM2/SOX9/BMP8A/NOTCH1/SFRP1/ZNF423/UBE2D3/FKBP8/WNT5A/MSX1/RYR2/CDH5/FBN1/SPINT2/ADAMTS12/CHRDL1	41
BP	GO:0071773	cellular response to BMP stimulus	41/2486	170/18670	9.254e-05	0.00333	0.00261	ACVR1/PELO/HTRA1/RGMA/HEYL/USP9Y/SMAD7/FSTL1/SORL1/HES1/RBPMS2/PCSK6/TWSG1/MIR21/SMPD3/SMAD1/BMP2/HTRA3/SFRP2/ACVR2A/SKIL/ITGA3/SULF1/SFRP4/PPM1A/GREM2/SOX9/BMP8A/NOTCH1/SFRP1/ZNF423/UBE2D3/FKBP8/WNT5A/MSX1/RYR2/CDH5/FBN1/SPINT2/ADAMTS12/CHRDL1	41
BP	GO:0034109	homotypic cell-cell adhesion	24/2486	81/18670	9.416e-05	0.003367	0.002639	HBB/ITGB3/MYL9/SH2B3/PEAR1/GATA1/CD9/GAS6/STXBP1/P2RY12/JUP/HSPB1/PDPN/PDGFRA/CEACAM1/C1QTNF1/MYH9/FLNA/LYN/METAP1/CSRP1/GP1BA/XG/ABAT	24
BP	GO:0009615	response to virus	68/2486	326/18670	9.464e-05	0.003367	0.002639	CLU/IFI27/PMAIP1/TNFAIP3/FADD/HTRA1/ARF1/IFI44/MAPK11/TRIM6/LYST/EIF2AK4/VWCE/IRF1/TNF/DHX9/IFITM3/LCN2/IFI16/SAMHD1/ITCH/ADARB1/GPATCH3/MAP3K14/PARP9/ZC3H12A/DDX21/RTP4/ILF3/PQBP1/BCL2L1/IL23R/IFIH1/HSPB1/PML/RELA/CXCL12/TSPAN6/SERINC3/IL12A/IFIT3/IFIT1/RNF216/IFIT5/HNRNPUL1/IFI6/DTX3L/DCLK1/IFITM2/IL1B/IL33/SKP2/RNF125/FLNA/TLR9/CCL8/CNOT7/BATF3/ACTA2/PCBP2/PTPRC/RSAD2/ABCE1/SETD2/HYAL1/SIN3A/ZCCHC3/TRIM44	68
BP	GO:0030510	regulation of BMP signaling pathway	26/2486	91/18670	9.623e-05	0.003396	0.002662	PELO/HTRA1/SMAD7/FSTL1/SORL1/HES1/RBPMS2/PCSK6/TWSG1/HTRA3/SFRP2/SKIL/ITGA3/SULF1/SFRP4/PPM1A/GREM2/NOTCH1/SFRP1/ZNF423/FKBP8/WNT5A/MSX1/CDH5/FBN1/CHRDL1	26
BP	GO:0003416	endochondral bone growth	16/2486	44/18670	9.656e-05	0.003396	0.002662	COCH/COL6A1/EVC/SCARA3/ECM1/STC1/COL27A1/COL14A1/THBS3/MATN2/VIT/COL12A1/COL21A1/DDR2/VWA1/COL6A2	16
BP	GO:0045766	positive regulation of angiogenesis	47/2486	204/18670	9.882e-05	0.003456	0.002709	ANXA3/CHI3L1/DDAH1/PDPK1/PRKCB/TWIST1/FLT1/GHRL/VEGFC/HIPK1/NRP1/CX3CL1/MIR21/SMAD1/ZC3H12A/FGF18/RAPGEF3/ANGPTL4/SIRT1/JUP/ECM1/NOS3/JAK1/HSPB1/SFRP2/SMOC2/RAMP2/RHOJ/PAK4/SRPX2/AGTR1/AQP1/KLF4/APLNR/TIE1/CD34/IL1B/TEK/HSPB6/ANGPT2/ITGB8/WNT5A/CDH5/MAP3K3/KDR/HYAL1/CCBE1	47
BP	GO:0018108	peptidyl-tyrosine phosphorylation	74/2486	363/18670	0.0001032	0.003587	0.002812	ITGB3/DSTYK/ACVR1/SH2B3/BMX/NTF3/SH3BP5L/GATA1/BDNF/CLK1/TNF/FLT1/PPP2CA/GHRL/UNC119/TGFB1/TAL1/HES1/NRP1/GAS6/CRLF1/ACE/FBXW7/ADRA2A/PARP9/IGF1R/CHMP6/BTK/THBS4/EGFR/NTRK2/IL23R/JAK1/SFRP2/SEMA4D/IGF1/EGF/EPHB4/PDGFRA/CBL/IL12A/MELK/IL2/CLK3/PDGFRB/AFAP1L2/TNFRSF14/TIE1/TEK/IBTK/NEDD9/SFRP1/THY1/TREM2/ENPP2/NOX4/EFEMP1/ROR1/CD300A/CNOT7/DDR2/PKDCC/CAV1/HCLS1/CSPG4/TTK/INPP5F/MTOR/LYN/GHR/KDR/EPHB2/PTPRC/AXL	74
BP	GO:0061138	morphogenesis of a branching epithelium	43/2486	182/18670	0.0001048	0.003626	0.002842	LRP5L/SPRY2/ACVR1/CSF1/PBX1/TNF/DLG1/TGFB1/PHB2/SPRY1/NRP1/BMP2/NFATC4/SFRP2/PML/NPNT/EGF/SIX1/COL4A1/HOXB7/STK4/SULF1/SMO/RSPO3/FRS2/SOX9/NOTCH1/YAP1/GLI3/HOXA11/PLXNA1/SFRP1/FZD5/WNT5A/ADAMTS16/SIX2/SLIT2/NTN4/GZF1/SEMA3E/TNC/SPINT2/LRP5	43
BP	GO:0003418	growth plate cartilage chondrocyte differentiation	11/2486	24/18670	0.000107	0.003681	0.002885	COCH/COL6A1/SCARA3/COL27A1/COL14A1/MATN2/VIT/COL12A1/COL21A1/VWA1/COL6A2	11
BP	GO:0030522	intracellular receptor signaling pathway	60/2486	280/18670	0.0001095	0.003747	0.002936	RBM14/ARID1A/GRIP1/NCOA3/TNFAIP3/FHL2/PPARG/EP300/HEYL/RNF6/NFKBIA/KDM5D/TWIST1/FABP5/DNAJA1/CRKL/SAFB2/FKBP4/PHB2/RXRB/KANK2/UBA52/ITCH/GPATCH3/CYP26B1/THRB/ZBTB7A/DAB2/SIRT1/TRAF6/TRIM24/IFIH1/CYLD/PML/RELA/TSPAN6/DDX54/TGFB1I1/NR2F2/PRAME/NR1D2/YAP1/NR2F6/SFRP1/ALDH1A2/SKP2/NR3C1/UBC/RNF125/NR4A2/TBX1/TAF1/PER1/NCOA6/NR1H4/ALPK1/CNOT1/NR5A2/ZCCHC3/NCOA1	60
BP	GO:2001236	regulation of extrinsic apoptotic signaling pathway	38/2486	155/18670	0.0001138	0.003872	0.003035	CTTN/PMAIP1/ACVR1/FAIM2/TNFAIP3/FADD/INHBA/GATA1/TNF/BCL10/NOL3/STRADB/DEDD2/PDIA3/PRDX2/NRP1/CX3CL1/RAF1/ITPRIP/BCL2L1/CYLD/NOS3/SFRP2/PML/SKIL/IGF1/RELA/STK4/TIMP3/MCL1/IFI6/YAP1/IL1B/STX4/SFRP1/CAV1/MADD/PTPRC	38
BP	GO:0019058	viral life cycle	68/2486	328/18670	0.0001147	0.003881	0.003042	ITGB3/IFI27/SLPI/ITGB5/STOM/TRIM6/EIF2AK4/CAV2/TNF/LTF/NUP93/IFITM3/TRIM21/IFI16/UBA52/GAS6/ITCH/TNIP1/ADARB1/SRPK2/PPID/LARP1/VPS37A/ZC3H12A/CHMP6/NUP50/ILF3/KPNA1/CHMP1B/EGFR/PML/NUP153/NUP210/VCP/KPNA3/VPS37B/RAE1/NUP188/NUP160/NUP54/IFIT1/EFNB2/NUP214/IDE/NUP155/IFIT5/TNFRSF14/NOTCH1/LRSAM1/IFITM2/UBC/UVRAG/PKN2/LRRC15/CCL8/CNOT7/HSP90AB1/CAV1/GYPA/ITGA2/GPR15/PCBP2/STAU1/RSAD2/HYAL1/AXL/DDX6/NR5A2	68
BP	GO:0033135	regulation of peptidyl-serine phosphorylation	35/2486	139/18670	0.0001183	0.003968	0.00311	SPRY2/ARAF/NTF3/BAG4/TRIM6/SNCA/TNF/SMAD7/TGFB1/PINK1/GAS6/HSP90AA1/RAF1/BDKRB2/RAPGEF3/EGFR/NTRK2/SFRP2/STK4/BCAR3/RAMP3/NSD1/PDCD10/PPM1F/WNT5A/HSP90AB1/CAV1/HCLS1/INPP5F/BAK1/SH2D3C/TNKS1BP1/DMD/MAPKAP1/RASSF2	35
BP	GO:0043491	protein kinase B signaling	58/2486	269/18670	0.0001186	0.003968	0.00311	SIRT2/SPRY2/CHI3L1/SH2B3/SLC9A3R1/NRG4/PEAR1/BAG4/TNF/DLG1/TGFB1/PINK1/GAS6/PHLDA3/CX3CL1/HSP90AA1/MIR21/SMPD3/FLCN/P2RY12/IGF1R/FGF18/SIRT1/SESN2/DDIT3/EGFR/NTRK2/LOX/VAV1/IGF1/EGF/PDGFRA/AKR1C2/IRS2/IGFBP5/PIK3CD/SESN3/C1QTNF1/RAMP3/PLK3/FRS2/KLF4/PDGFRB/MTM1/SOX9/IL1B/TEK/CCL21/NOX4/IL26/MAGI2/HSP90AB1/HCLS1/INPP5F/MTOR/KDR/KL/AXL	58
BP	GO:0060537	muscle tissue development	81/2486	408/18670	0.0001264	0.004208	0.003298	SIRT2/ARID1A/ACVR1/YY1/MEF2D/EP300/HEYL/MYL6B/MAPK11/TBX5/CAV2/TWIST1/SMAD7/DLG1/TGFB2/AKIRIN1/TGFB1/TPM1/CREB1/KDM6B/AKAP13/TIPARP/CYP26B1/GJA5/FLCN/SMAD1/FOXC1/BMP2/HLX/FOS/SGCD/ELN/LOX/OBSL1/CCNT2/IGF1/ADAMTS9/UBE4B/SIX1/HLF/PDGFRA/MIR17HG/NR2F2/IGFBP5/NR1D2/ALPK3/EFNB2/CDON/SMO/POU4F1/FRS2/MEOX2/PDGFRB/MTM1/NUPR1/SOX9/TBX2/KLF5/NOTCH1/SHOX2/YAP1/JARID2/BTG2/ALDH1A2/GPC1/ZFPM2/CSRP2/NOX4/WNT5A/SGCB/DCN/RYR2/ALPK2/TBX1/CAV1/MTOR/MYH10/CSRP1/SOX6/HOXD9/PIN1	81
BP	GO:0016573	histone acetylation	38/2486	156/18670	0.0001315	0.004353	0.003412	MUC1/PHF20/NCOA3/POLE3/MSL2/EP300/SNCA/TAF10/TWIST1/HAT1/YEATS2/TGFB1/LDB1/ING3/WDR5/FLCN/CREBBP/IRF4/TRRAP/GTF3C4/SIRT1/SETD5/RSF1/MORF4L2/HCFC1/MCM3AP/IL1B/EP400/CHD5/PCGF2/SET/TAF1/RPS6KA5/EPC1/PER1/SIN3A/NCOA1/ING5	38
BP	GO:0030213	hyaluronan biosynthetic process	8/2486	14/18670	0.0001388	0.004571	0.003583	TGFB1/SMPD3/EGF/HAS2/IL1B/HAS3/HAS1/HYAL1	8
BP	GO:0050673	epithelial cell proliferation	85/2486	434/18670	0.0001413	0.004629	0.003628	ITGB3/IQGAP3/PDPK1/TNFAIP3/EDNRB/PPARG/ITGA4/HTRA1/SPARC/ARG1/CAV2/TNF/TWIST1/FLT1/JUN/LIMS2/CD109/DLG1/DUSP10/GHRL/TGFB2/VEGFC/LAMC1/TGFB1/PHB2/ZFP36/HES1/CDKN1C/NRP1/FBXW7/CCND1/ERN1/MIR21/BMP2/EGFL7/NFIB/SIRT1/THBS4/EGFR/ECM1/SFRP2/ACVR2A/WFDC1/MTSS1/IGF1/CXCL12/VASH1/PTN/SIX1/IGFBP4/CEACAM1/NR2F2/IGFBP5/AGTR1/SULF1/EFNB2/SMO/FRS2/APLNR/HAS2/NUPR1/SOX9/CD34/NOTCH1/NOTCH2/YAP1/TEK/FAP/SFRP1/ALDH1A2/CDKN2B/LAMB1/PDCD10/RREB1/WNT5A/IL26/TBX1/CAV1/MTOR/KDR/INTU/MST1/HYAL1/IGFBP3/THAP1	85
BP	GO:0033273	response to vitamin	26/2486	93/18670	0.0001425	0.004645	0.003641	PPARG/SPARC/ARG1/TGFB1/KANK2/GAS6/CYP26B1/CCND1/ALPL/SPP1/PHEX/EGFR/TRIM24/STC1/RELA/PTN/FKBP1B/SFRP1/ALDH1A2/HMGCS1/STC2/POSTN/ITGA2/TNC/MGMT/MTHFR	26
BP	GO:0048545	response to steroid hormone	77/2486	385/18670	0.0001437	0.00466	0.003652	RBM14/ANXA3/ARID1A/GRIP1/NCOA3/FHL2/FOSB/PPARG/SPARC/ARG1/EP300/HEYL/RNF6/KDM5D/TNF/DNAJA1/TGFB2/CDO1/TGFB1/SAFB2/IGFBP2/FKBP4/PHB2/RXRB/TRH/KANK2/ZFP36/AKAP13/CCND1/PAM/THRB/ZBTB7A/ALPL/FOS/DAB2/SIRT1/SPP1/EGFR/HSD11B2/LOX/STC1/RELA/CATSPER3/PTN/ASS1/CPN1/RAMP2/TFPI/DDX54/TGFB1I1/NR2F2/NR1D2/AQP1/NOTCH1/YAP1/NR2F6/CPS1/SFRP1/SKP2/NR3C1/OXTR/REST/FAM107A/NCOA2/NR4A2/DUSP1/CAV1/SLIT2/ADCYAP1/TAF1/PER1/NCOA6/NR1H4/FIBIN/CNOT1/NR5A2/NCOA1	77
BP	GO:0010172	embryonic body morphogenesis	7/2486	11/18670	0.0001486	0.004786	0.003751	CLASP2/PHLDB2/CDON/GREM2/ZNF281/MAB21L2/CLASP1	7
BP	GO:0051258	protein polymerization	60/2486	283/18670	0.0001492	0.004786	0.003751	RHOBTB1/CTTN/ARHGAP18/EPS8/TTC17/FGF13/ARHGAP6/TMOD1/BAG4/MYADM/NAV3/ARF1/WASF3/CLIP3/TRIM6/SNCA/DLG1/PINK1/FKBP4/CLASP2/DIAPH1/HSP90AA1/CEP192/ELN/UBE2S/AVIL/COTL1/AP1AR/NIN/MAP2/PFN4/LMOD1/ARHGAP28/WHAMM/WASF1/MYO1C/CAPZA1/UBE2C/TMSB4Y/FCHSD2/CCL21/CDK5R1/DIAPH3/NCKAP1/TMSB15A/PAK3/MIR214/FAM107A/NDE1/ARPC2/CDH5/SLIT2/HCLS1/MTOR/CLASP1/KANK3/PFN1/CDC42EP5/CORO1A/MAGEL2	60
BP	GO:0007584	response to nutrient	49/2486	219/18670	0.0001527	0.004876	0.003821	PPARG/SPARC/ARG1/BCL11A/HSP90B1/LPL/HAT1/TGFB1/SSH1/IGFBP2/C2/CREB1/KANK2/GAS6/CYP26B1/CCND1/P2RY12/ALPL/SPP1/PHEX/EGFR/TRIM24/SFRP2/STC1/P2RX7/RELA/ADIPOR2/PTN/ASS1/P2RY2/CIB2/IL1B/FKBP1B/SFRP1/ALDH1A2/CDKN2B/HMGCS1/STC2/MTOR/POSTN/ITGA2/TAF1/TNC/MGMT/NR1H4/NQO1/MTHFR/HMGCL/NCOA1	49
BP	GO:0031076	embryonic camera-type eye development	14/2486	37/18670	0.0001602	0.005086	0.003987	ARID1A/TWIST1/PHACTR4/HIPK1/WDR19/SP3/FRS2/IFT140/TBX2/ALDH1A3/ALDH1A2/NES/FZD5/WNT5A	14
BP	GO:0046822	regulation of nucleocytoplasmic transport	28/2486	104/18670	0.0001639	0.00518	0.00406	IFI27/RBM4/RBM22/AKAP8L/DHX9/TGFB1/GAS6/NOLC1/ZC3H12A/RAPGEF3/JUP/NUP153/NUP54/PPM1A/NUP214/SMO/GLI3/IL1B/KHDRBS1/PTPN14/RANGAP1/IPO5/FLNA/HCLS1/ANP32B/UHMK1/BARD1/SETD2	28
BP	GO:0021952	central nervous system projection neuron axonogenesis	11/2486	25/18670	0.0001682	0.005288	0.004145	SCN1B/ADARB1/NFIB/NIN/DCLK1/TSKU/NR4A2/SLIT2/MYCBP2/EPHB2/CDH11	11
BP	GO:0001914	regulation of T cell mediated cytotoxicity	13/2486	33/18670	0.0001702	0.005323	0.004172	FAM49B/CD1C/FADD/FCGR2B/CD1B/IL23R/P2RX7/HLA-B/CEACAM1/IL12A/PPP3CB/PTPRC/HLA-A	13
BP	GO:0051222	positive regulation of protein transport	82/2486	418/18670	0.0001737	0.005362	0.004202	ABLIM3/SRI/ORM1/SYTL4/MMP8/STOM/RBM22/MBP/EDEM1/ARF1/MFF/MAPK11/TRIM6/TNF/TWIST1/LPL/GHRL/TGFB2/FRMD4A/VEGFC/DHX9/CD244/TGFB1/PINK1/SERP1/SORL1/TRH/PFKFB2/C2CD2L/ARIH2/CACNB3/GAS6/FBXW7/PPID/ZC3H12A/RAPGEF3/PTGER4/TM7SF3/JUP/EGFR/IFIH1/P2RX7/SEC16A/IGF1/IRS2/PPM1A/IL2/SMO/PLK3/MYO1C/TNFRSF14/CD34/GLI3/IL1B/STX4/ZFAND1/IL33/TREM2/PPP3CB/PSMD9/FZD5/CDK5R1/UBE2D3/NLRP1/PDCD10/IPO5/WNT5A/FLNA/IL26/PARD6A/CAPN10/HCLS1/SLC35D3/POSTN/FRMD8/MYH10/PDCD5/ANP32B/UNC13B/NR1H4/ABAT/NLRP7	82
BP	GO:0060536	cartilage morphogenesis	12/2486	29/18670	0.000174	0.005362	0.004202	COCH/COL6A1/SCARA3/STC1/COL14A1/MATN2/VIT/COL12A1/COL21A1/MSX1/VWA1/COL6A2	12
BP	GO:1900034	regulation of cellular response to heat	23/2486	79/18670	0.0001749	0.005362	0.004202	IER5/CAMK2G/BAG4/EP300/NUP93/FKBP4/HSP90AA1/CREBBP/NUP50/SIRT1/NUP153/NUP210/RAE1/NUP188/NUP160/NUP54/NUP214/NUP155/CD34/HSP90AB1/MTOR/CRYAB/HSPB8	23
BP	GO:0007266	Rho protein signal transduction	46/2486	203/18670	0.0001757	0.005362	0.004202	RHOBTB1/EPS8/ARHGAP6/RTKN/SCAI/ARHGEF37/LPAR6/RND2/KANK2/PHACTR4/CTNNAL1/AKAP13/NRP1/RHOF/ADRA2A/FLCN/RAF1/GPR4/ARHGEF7/FGD5/VAV1/LPAR4/GPR35/PDPN/ITGA3/PLEKHG5/ITSN2/RND3/RHOJ/AGTR1/RND1/FARP1/PDGFRB/ARHGAP29/ARHGEF16/VAV3/FGD3/P2RY8/SOS2/DLC1/TNFAIP1/CDC42EP5/ARHGEF12/ARHGEF15/EPS8L1/COL1A2	46
BP	GO:0030278	regulation of ossification	46/2486	203/18670	0.0001757	0.005362	0.004202	ACVR1/JUND/GATA1/BCOR/CSF1/NIPBL/PBX1/TMEM119/TNF/TWIST1/LTF/TGFB2/TGFB1/TWSG1/MIR21/SMAD1/BMP2/FBN2/PTGER4/TWIST2/ECM1/SFRP2/SEMA4D/P2RX7/NPNT/ACVR2A/IGF1/PTN/IGFBP5/SOX9/SMOC1/NOTCH1/GLI3/ANKH/CTHRC1/SFRP1/REST/WNT5A/DDR2/PKDCC/SIX2/INTU/KL/MGP/LRP5/RASSF2	46
BP	GO:0008154	actin polymerization or depolymerization	47/2486	209/18670	0.0001817	0.005476	0.004292	RHOBTB1/CTTN/ARHGAP18/EPS8/TTC17/CIT/ARHGAP6/TMOD1/BAG4/MYADM/ARF1/WASF3/DLG1/GHRL/DIAPH1/ELN/AVIL/CXCL12/COTL1/AP1AR/PFN4/LMOD1/ARHGAP28/PLEKHH2/WHAMM/WASF1/ENAH/MYO1C/CAPZA1/TMSB4Y/FCHSD2/CCL21/DIAPH3/NCKAP1/TMSB15A/PAK3/MIR214/FAM107A/ARPC2/SLIT2/HCLS1/MTOR/KANK3/PFN1/CDC42EP5/CORO1A/MAGEL2	47
BP	GO:0034976	response to endoplasmic reticulum stress	60/2486	285/18670	0.0001824	0.005476	0.004292	CLU/PMAIP1/SEC61B/PPP1R15A/PPP1R15B/ITPR1/MBTPS1/EDEM1/CASP4/EP300/SDF2L1/HSP90B1/EIF2AK4/JUN/PDIA3/SERP1/HYOU1/HERPUD1/EIF2S1/FCGR2B/CCND1/ERN1/ERLIN1/ERP29/UBXN1/DNAJB14/SSR1/DNAJC10/RNF183/DDX11/SIRT1/SESN2/THBS4/DDIT3/BCL2L1/DERL1/SEC16A/ERLIN2/PML/TBL2/MAP3K5/UBE4B/VCP/SERINC3/CREB3L1/NUPR1/STT3B/KDELR3/UBE2G2/RNF139/RNF103/TMUB2/CAV1/AUP1/STC2/BAK1/TMEM67/WFS1/HSPA5/SDF2	60
BP	GO:0048608	reproductive structure development	84/2486	431/18670	0.0001825	0.005476	0.004292	ARID1A/MAMLD1/MME/PPARG/HTRA1/INHBA/GATA1/NIPBL/RAB13/TAF4/DLG1/GHRL/TGFB2/CRKL/ZFAT/STOX2/SAFB2/FKBP4/HES1/CDKN1C/ARID4A/TIPARP/CCND1/SMARCC1/FOXC1/WDR19/SIRT1/SPP1/SP3/EGFR/BCL2L1/NOS3/SFRP2/STC1/ACVR2A/VASH1/PTN/PDGFRA/CBL/STK4/NR2F2/HOXA10/SULF1/RSPO3/FRS2/MMP19/PDGFRB/NUPR1/SOX9/NDP/NOTCH1/DLX3/GLI3/HOXA11/SFRP1/RXFP2/ZFPM2/NUP210L/FZD5/BPTF/ITGB8/WNT5A/DCN/FLNA/HMGCS1/HSP90AB1/SLIT2/STC2/HSD17B3/HOXA9/BAK1/ADCYAP1/E2F8/FZD4/HSPA5/TNC/SPINT2/JUNB/SETD2/AXL/EIF2B2/LHX8/ZNF830/NCOA1	84
BP	GO:0032147	activation of protein kinase activity	68/2486	333/18670	0.000183	0.005476	0.004292	ITGB3/ADCY3/CHI3L1/IQGAP3/NTF3/FGF13/PDPK1/PPP2R3C/MAPK11/PRKAR2A/ADCY7/TNF/DLG1/GHRL/TGFB2/CRKL/STRADB/PINK1/PRDX2/ADCY4/TRAF4/UBA52/GAS6/ERN1/ADRA2A/ERP29/STK24/RPLP1/MAP3K14/MIR21/TPX2/RAF1/BMP2/TRAF6/MAP3K2/EGFR/IL23R/ADCY6/P2RX7/MAP3K5/MAP3K1/IGF1/CARD10/EGF/PAK4/STK10/STK4/FRS2/EMP2/PRKAG2/IL1B/CDK5R1/UBC/WNT5A/PAK3/CD300A/MAP3K3/MAPKAPK5/CSPG4/MADD/MTOR/GHR/PDE6G/PRKAR2B/MAPKAP1/PTPRC/KIF14/ZFP91	68
BP	GO:1904951	positive regulation of establishment of protein localization	88/2486	456/18670	0.0001843	0.005491	0.004303	ABLIM3/SRI/PMAIP1/ORM1/SYTL4/MMP8/STOM/RBM22/MBP/EDEM1/ARF1/MFF/MAPK11/TRIM6/TNF/TWIST1/LPL/GHRL/TGFB2/FRMD4A/VEGFC/DHX9/CD244/TGFB1/PINK1/SERP1/SORL1/TRH/PFKFB2/C2CD2L/PTP4A3/ARIH2/CACNB3/GAS6/FBXW7/PPID/ZC3H12A/RAPGEF3/PTGER4/TM7SF3/JUP/EGFR/IFIH1/P2RX7/SEC16A/IGF1/CEP135/YWHAZ/IRS2/PPM1A/IL2/SMO/PLK3/CCT8/MYO1C/TNFRSF14/CD34/GLI3/IL1B/STX4/ZFAND1/IL33/TREM2/PPP3CB/PSMD9/FZD5/CDK5R1/UBE2D3/NLRP1/PDCD10/IPO5/WNT5A/FLNA/IL26/PARD6A/TP53BP2/CAPN10/HCLS1/SLC35D3/POSTN/FRMD8/MYH10/PDCD5/ANP32B/UNC13B/NR1H4/ABAT/NLRP7	88
BP	GO:0034332	adherens junction organization	35/2486	142/18670	0.0001858	0.005508	0.004317	TRIP6/CTTN/ARHGAP6/PDPK1/SMAD7/LDB1/HIPK1/NRP1/PLEKHA7/CLASP2/COL16A1/ARHGEF7/JUP/CDH26/RAMP2/PHLDB2/FERMT2/WHAMM/ACTN1/TEK/SFRP1/SORBS1/THY1/CADM3/LIMS1/PPM1F/FAM107A/CDH5/CLASP1/DLC1/KDR/ITGA2/CDH6/LIMCH1/CDH11	35
BP	GO:1903706	regulation of hemopoiesis	91/2486	475/18670	0.000188	0.005547	0.004347	MYL9/KLF13/PSMD14/C1QC/PSMD12/INPP5D/FADD/CNOT4/INHBA/EP300/PPP2R3C/GATA1/NFKBIA/CSF1/PRKCB/PGLYRP1/IRF1/TNF/SMAD7/JUN/YTHDF2/HOXA7/DUSP10/TRIM58/LTF/TGFB1/PSMD7/TAL1/PSMB5/LDB1/PRDX2/CREB1/TNRC6B/ZFP36/HES1/GAS6/ITCH/ACE/FBXW7/CYP26B1/FCGR2B/WDR5/CD83/MIR21/FLCN/CREBBP/ZC3H12A/IRF4/FOXC1/NFKBIZ/HLX/FOS/BTK/TRAF6/LOX/IL23R/CYLD/MEIS2/ACVR2A/PTN/MIR17HG/CEACAM1/KLF10/IL12A/IL2/POU4F1/PSMB7/RAB7B/NOTCH1/NOTCH2/YAP1/GLI3/IL17D/PSMD1/SFRP1/TREM2/PSMD9/TLR9/HCLS1/MTOR/LYN/HOXA9/FBN1/PSME1/GP1BA/RC3H1/PTPRC/SIN3A/AXL/HSPA9/RASSF2	91
BP	GO:0000209	protein polyubiquitination	64/2486	310/18670	0.0002028	0.005955	0.004667	IFI27/MYLIP/PSMD14/PSMD12/SPSB1/TNFAIP3/RNF6/TRIM6/TRIM58/PSMD7/PSMB5/KLHL20/FBXO41/TRIM21/ARIH2/UBA52/RMND5A/ITCH/FBXO38/FBXW7/FBXW8/FBXO4/RNF213/RNF183/TRAF6/UBE2S/HECW2/UBE4B/TPP2/CBL/UBE3C/ANAPC10/WSB1/FBXL13/FBXL8/RNF216/TRIM2/PSMB7/RLIM/LRSAM1/DTX3L/UBE2C/HECTD1/PSMD1/PSMD9/SKP2/UBC/UBE2D3/RNF125/FBXL14/UBE2G2/RNF19B/CHFR/ARIH1/TAF1/PSME1/RC3H1/BARD1/MAGEL2/ZFP91/CUL1/RNF8/TRIM44/FBXW2	64
BP	GO:0009408	response to heat	41/2486	176/18670	0.0002071	0.00603	0.004726	IER5/CAMK2G/BAG4/EP300/DNAJA1/NUP93/FKBP4/EIF2S1/HSP90AA1/CREBBP/HSF4/NUP50/ARPP21/SIRT1/STAC/NOS3/IGF1/CXCL12/NUP153/NUP210/VCP/RAE1/NUP188/NUP160/TGFB1I1/NUP54/DNAJA4/LRP11/NUP214/NUP155/CD34/HSP90AB1/MTOR/LYN/DNAJA2/HSPA5/POLR2D/CRYAB/HSPB8/HSPA9/EIF2B2	41
BP	GO:0045069	regulation of viral genome replication	26/2486	95/18670	0.0002077	0.00603	0.004726	IFI27/SLPI/STOM/TRIM6/EIF2AK4/TNF/LTF/IFITM3/IFI16/TNIP1/ADARB1/SRPK2/PPID/LARP1/ZC3H12A/ILF3/IFIT1/IFIT5/NOTCH1/IFITM2/PKN2/CCL8/CNOT7/STAU1/RSAD2/NR5A2	26
BP	GO:0002709	regulation of T cell mediated immunity	21/2486	70/18670	0.0002083	0.00603	0.004726	FAM49B/CD1C/FADD/ARG1/SMAD7/IL1R1/FBXO38/FCGR2B/CD1B/TRAF6/IL23R/P2RX7/HLA-B/CEACAM1/IL12A/IL1B/PPP3CB/FZD5/PTPRC/RSAD2/HLA-A	21
BP	GO:0014031	mesenchymal cell development	24/2486	85/18670	0.0002144	0.006152	0.004821	ACVR1/PEF1/EDNRB/SEMA3B/HEYL/TWIST1/SEMA3G/PHACTR4/HES1/NRP1/NOLC1/FN1/FOXC1/EDN3/SEMA4D/SEMA6D/SEMA5B/SMO/SOX9/NOTCH1/ALDH1A2/TBX1/SEMA3E/TCOF1	24
BP	GO:0048864	stem cell development	24/2486	85/18670	0.0002144	0.006152	0.004821	ACVR1/PEF1/EDNRB/SEMA3B/TWIST1/SEMA3G/PHACTR4/HES1/NRP1/NOLC1/FN1/FOXC1/EDN3/SEMA4D/SEMA6D/SEMA5B/SMO/SOX9/ALDH1A2/TBX1/SEMA3E/PTPRC/TCOF1/SETD2	24
BP	GO:0040013	negative regulation of locomotion	78/2486	396/18670	0.0002164	0.00617	0.004835	SLC9A3R1/PTPRO/PPARG/SEMA3B/C5orf30/NAV3/SCAI/PLXNA3/TBX5/SMAD7/HOXA7/DUSP10/GHRL/TGFB1/SRGAP1/TPM1/ELANE/SEMA3G/TRIM21/CYGB/NRP1/ADARB1/CLASP2/STK24/CX3CL1/MIR21/FLCN/PTGER4/MMRN2/JUP/SFRP2/STC1/SEMA4D/PML/CXCL12/ADAMTS9/CARD10/SEMA6D/SEMA5B/VASH1/PTN/AP1AR/PLCB1/PHLDB2/NR2F2/DNAJA4/IGFBP5/DPYSL3/SULF1/MEOX2/KLF4/TIE1/NOTCH1/PTPRG/CCL21/SFRP1/IL33/THY1/ANGPT2/PDCD10/FBLN1/WNT5A/MIR214/DCN/HAS1/MAGI2/DUSP1/CD300A/SLIT2/CLASP1/GPR173/DLC1/SEMA3E/SPINT2/LIMCH1/IGFBP3/PIN1/ADORA3	78
BP	GO:0030041	actin filament polymerization	42/2486	182/18670	0.000217	0.00617	0.004835	RHOBTB1/CTTN/ARHGAP18/EPS8/TTC17/ARHGAP6/TMOD1/BAG4/MYADM/ARF1/WASF3/DLG1/DIAPH1/ELN/AVIL/COTL1/AP1AR/PFN4/LMOD1/ARHGAP28/WHAMM/WASF1/MYO1C/CAPZA1/TMSB4Y/FCHSD2/CCL21/DIAPH3/NCKAP1/TMSB15A/PAK3/MIR214/FAM107A/ARPC2/SLIT2/HCLS1/MTOR/KANK3/PFN1/CDC42EP5/CORO1A/MAGEL2	42
BP	GO:0051271	negative regulation of cellular component movement	76/2486	384/18670	0.0002221	0.006283	0.004925	SLC9A3R1/PTPRO/PPARG/SEMA3B/C5orf30/NAV3/SCAI/PLXNA3/TBX5/CD9/SMAD7/HOXA7/DUSP10/TGFB1/SRGAP1/TPM1/SEMA3G/CYGB/NRP1/ADARB1/CLASP2/STK24/CX3CL1/MIR21/FLCN/PTGER4/MMRN2/JUP/SFRP2/STC1/SEMA4D/CXCL12/ADAMTS9/CARD10/SEMA6D/SEMA5B/VASH1/PTN/AP1AR/PLCB1/PHLDB2/NR2F2/DNAJA4/IGFBP5/DPYSL3/SULF1/ACTN1/MEOX2/KLF4/TIE1/NOTCH1/PTPRG/CCL21/SFRP1/IL33/THY1/ANGPT2/PDCD10/FBLN1/WNT5A/MIR214/DCN/HAS1/MAGI2/DUSP1/CD300A/SLIT2/CLASP1/GPR173/DLC1/SEMA3E/SPINT2/LIMCH1/IGFBP3/PIN1/ADORA3	76
BP	GO:0007389	pattern specification process	86/2486	446/18670	0.0002231	0.006283	0.004925	C1QA/LRP5L/TRA2B/ACVR1/SIM2/C9orf116/HOXB5/GAS8/YY1/IRX2/EP300/HEYL/APC/BCOR/TBX5/PBX1/BHLHE41/HOXA7/CRKL/LDB1/PBX2/DAAM2/BHLHE40/SPRY1/HIPK1/HES6/HES1/MEOX1/NRP1/PCSK6/CYP26B1/SMAD1/FOXC1/BMP2/IRX3/WDR19/DDIT3/ASPH/SFRP2/STC1/DMRT3/ACVR2A/HOXC10/HOXC6/SATB2/SIX1/HOXB7/MFNG/HOXD8/NR2F2/HOXA10/MID1/CDON/SMO/FRS2/MEOX2/IFT140/GREM2/TBX2/NOTCH1/GLI3/HOXA11/HOXC9/BTG2/SFRP1/C2CD3/ALDH1A2/FZD5/BPTF/FKBP8/WNT5A/MSX1/EMX2/TBX1/SSBP3/PCGF2/SIX2/HOXA9/DNAH5/INTU/PALB2/HOXC5/ARC/HOXA3/LRP5/HOXD9	86
BP	GO:0061458	reproductive system development	84/2486	434/18670	0.0002312	0.006443	0.00505	ARID1A/MAMLD1/MME/PPARG/HTRA1/INHBA/GATA1/NIPBL/RAB13/TAF4/DLG1/GHRL/TGFB2/CRKL/ZFAT/STOX2/SAFB2/FKBP4/HES1/CDKN1C/ARID4A/TIPARP/CCND1/SMARCC1/FOXC1/WDR19/SIRT1/SPP1/SP3/EGFR/BCL2L1/NOS3/SFRP2/STC1/ACVR2A/VASH1/PTN/PDGFRA/CBL/STK4/NR2F2/HOXA10/SULF1/RSPO3/FRS2/MMP19/PDGFRB/NUPR1/SOX9/NDP/NOTCH1/DLX3/GLI3/HOXA11/SFRP1/RXFP2/ZFPM2/NUP210L/FZD5/BPTF/ITGB8/WNT5A/DCN/FLNA/HMGCS1/HSP90AB1/SLIT2/STC2/HSD17B3/HOXA9/BAK1/ADCYAP1/E2F8/FZD4/HSPA5/TNC/SPINT2/JUNB/SETD2/AXL/EIF2B2/LHX8/ZNF830/NCOA1	84
BP	GO:0048592	eye morphogenesis	36/2486	149/18670	0.0002314	0.006443	0.00505	ARID1A/YY1/NIPBL/TWIST1/PHACTR4/HIPK1/THRB/FBN2/SP3/NTRK2/PTN/AGTPBP1/WNT9A/BCAR3/ROM1/SDK1/CDON/FAT1/FRS2/MFAP2/COL5A1/SOX9/TBX2/TSKU/ALDH1A3/GLI3/THY1/FZD5/WNT5A/EFEMP1/MAN2A1/BAK1/FBN1/EPHB2/COL5A2/LRP5	36
BP	GO:0062012	regulation of small molecule metabolic process	88/2486	459/18670	0.0002319	0.006443	0.00505	PSMD14/PMAIP1/PSMD12/PPTC7/PDPR/GNMT/MBTPS1/PPARG/ME1/EP300/SLC25A33/SNCA/TNF/TWIST1/FABP5/NUP93/CD244/TGFB1/PSMD7/PINK1/PSMB5/PFKFB2/ERLIN1/WDR5/MIR21/SMPD3/FLCN/NFYA/BMP2/ZBTB7A/NUP50/APOC1/SIRT1/SESN2/NOS3/P2RX7/ERLIN2/CBFA2T3/IGF1/ADIPOR2/NUP153/NUP210/GNB3/EGF/VCP/PTH1R/IGFBP4/RAE1/NUP188/COX7A1/CEACAM1/NUP160/IRS2/NUP54/HRH1/PDP1/C1QTNF1/NUP214/NUP155/PSMB7/FOXK2/KHK/HAS2/NUPR1/SLC2A6/PRKAG2/IL1B/PSMD1/SORBS1/TREM2/PSMD9/REST/NCOA2/WDTC1/AZIN1/HMGCS1/CAV1/MTOR/MST1/MIDN/PSME1/PDK4/DKK3/NR1H4/FABP3/ELOVL5/NQO1/IGFBP3	88
BP	GO:0061614	pri-miRNA transcription by RNA polymerase II	16/2486	47/18670	0.0002353	0.006509	0.005102	PPARG/YY1/JUN/TGFB2/TGFB1/SMAD1/BMP2/NFIB/FOS/NFATC4/RELA/KLF4/SOX9/KLF5/NR3C1/NFATC3	16
BP	GO:0033622	integrin activation	10/2486	22/18670	0.000241	0.006625	0.005192	FBLIM1/SELP/CX3CL1/P2RY12/FN1/COL16A1/PTGER4/CXCL12/FERMT2/KIF14	10
BP	GO:0048566	embryonic digestive tract development	13/2486	34/18670	0.0002422	0.006625	0.005192	NIPBL/TNF/TGFB2/SCT/RBPMS2/HLX/RARRES2/PDGFRA/SHOX2/GLI3/ALDH1A2/PKDCC/SIX2	13
BP	GO:0002244	hematopoietic progenitor cell differentiation	39/2486	166/18670	0.0002426	0.006625	0.005192	PLD4/PSMD14/PSMD12/INHBA/GATA1/YTHDF2/ZFAT/TGFB1/PSMD7/TAL1/PSMB5/LDB1/ANLN/HES1/MEOX1/ITCH/ACE/DHTKD1/SMPD3/FLCN/FOXC1/BATF/PDGFRA/PSMB7/PDGFRB/NOTCH1/YAP1/PSMD1/DACT2/SFRP1/PSMD9/REST/CHD2/SSBP3/EML1/PSME1/PTPRC/SIN3A/HSPA9	39
BP	GO:1990823	response to leukemia inhibitory factor	26/2486	96/18670	0.0002492	0.006745	0.005287	SPRY2/EPS8/BCLAF1/SLC25A5/SMAD7/VEGFC/PCOLCE2/CREB1/PTP4A3/NEFH/MRPL15/SIRT1/PML/PIGA/PCOLCE/KLF4/KLF5/PRDM5/JARID2/PDCD10/MAT2A/GFPT2/RNMT/FZD4/NR5A2/PFKP	26
BP	GO:1990830	cellular response to leukemia inhibitory factor	26/2486	96/18670	0.0002492	0.006745	0.005287	SPRY2/EPS8/BCLAF1/SLC25A5/SMAD7/VEGFC/PCOLCE2/CREB1/PTP4A3/NEFH/MRPL15/SIRT1/PML/PIGA/PCOLCE/KLF4/KLF5/PRDM5/JARID2/PDCD10/MAT2A/GFPT2/RNMT/FZD4/NR5A2/PFKP	26
BP	GO:0006109	regulation of carbohydrate metabolic process	46/2486	206/18670	0.0002507	0.006757	0.005296	PMAIP1/GNMT/EP300/MLXIP/SNCA/NUP93/CD244/TGFB1/PFKFB2/WDR5/SMPD3/ZBTB7A/NUP50/SIRT1/SESN2/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/GNB3/EGF/PTH1R/IGFBP4/RAE1/NUP188/NUP160/IRS2/NUP54/HRH1/C1QTNF1/NUP214/NUP155/FOXK2/KHK/HAS2/NUPR1/SLC2A6/PRKAG2/SORBS1/NCOA2/MTOR/MST1/MIDN/PDK4/IGFBP3	46
BP	GO:0043087	regulation of GTPase activity	91/2486	479/18670	0.0002532	0.006795	0.005326	SPRY2/ARHGAP18/IQGAP3/RABGAP1L/NTF3/EIF5/ARHGAP6/TBC1D10A/RTKN/TAGAP/PLXNA3/DEPDC5/ASAP2/CAV2/JUN/CRKL/SRGAP1/RAP1GAP2/AGRN/RGS7/SPRY1/ARHGAP10/NRP1/ASAP3/CX3CL1/MIR21/FLCN/ZC3H15/RAB3GAP2/RALGAPB/ARHGAP9/RAPGEF3/NUP50/RASAL2/RGS6/ARHGEF7/CCL13/FGD5/NTRK2/VAV1/SEMA4D/CHN2/DEPDC1/ARHGAP32/PLCB1/ARHGAP19/CHN1/FZD10/RGL3/TBC1D16/ARHGAP28/RIN3/PKP4/PLXNA1/ARHGAP29/NEDD9/CCL21/SFRP1/THY1/ARHGEF16/CHML/LIMS1/RANGAP1/VAV3/IPO5/WNT5A/FGD3/CCL8/ARFGAP2/ARHGAP30/TBC1D2B/SLIT2/ACAP2/MTOR/DLC1/ARHGAP11A/RGS14/GIT2/ADCYAP1/TBC1D9/GPSM1/ARHGEF12/RALGAPA2/RGS17/DOCK11/CCL18/ARHGEF15/DOCK8/PIN1/CPEB2/GDI1	91
BP	GO:0045948	positive regulation of translational initiation	12/2486	30/18670	0.000255	0.006814	0.00534	PPP1R15A/EIF2AK4/TNF/YTHDF2/YTHDF1/POLR2G/KHDRBS1/YTHDF3/MTOR/CDC123/UHMK1/POLR2D	12
BP	GO:0071711	basement membrane organization	11/2486	26/18670	0.0002566	0.006827	0.005351	PXDN/CLASP2/NID2/FLRT2/COL4A1/RAMP2/PHLDB2/LAMB1/NTN4/CLASP1/SPINT2	11
BP	GO:0018393	internal peptidyl-lysine acetylation	38/2486	161/18670	0.0002622	0.006947	0.005445	MUC1/PHF20/NCOA3/POLE3/MSL2/EP300/SNCA/TAF10/TWIST1/HAT1/YEATS2/TGFB1/LDB1/ING3/WDR5/FLCN/CREBBP/IRF4/TRRAP/GTF3C4/SIRT1/SETD5/RSF1/MORF4L2/HCFC1/MCM3AP/IL1B/EP400/CHD5/PCGF2/SET/TAF1/RPS6KA5/EPC1/PER1/SIN3A/NCOA1/ING5	38
BP	GO:0003179	heart valve morphogenesis	17/2486	52/18670	0.0002643	0.006962	0.005456	ACVR1/HEYL/TBX5/TWIST1/TGFB2/TGFB1/GJA5/BMP2/MDM4/ELN/NOS3/ADAMTS9/SOX9/NOTCH1/NOTCH2/SLIT2/MTOR	17
BP	GO:0050777	negative regulation of immune response	36/2486	150/18670	0.0002661	0.006962	0.005456	INPP5D/TNFAIP3/ARG2/PPARG/PARP3/ARG1/PGLYRP1/TNF/SMAD7/YTHDF2/DUSP10/TGFB2/CD59/TGFB1/IFI16/SAMHD1/FCGR2B/MIR21/ZC3H12A/HLX/SERPING1/CEACAM1/IL13RA2/IL2/SERPINB9/TNFRSF14/IL33/PPP3CB/YTHDF3/CD300A/CNOT7/LYN/ADCYAP1/A2M/RC3H1/PTPRC	36
BP	GO:0002218	activation of innate immune response	65/2486	319/18670	0.0002671	0.006962	0.005456	MUC1/RBM14/PSMD14/PSMD12/CLEC4C/PDPK1/TNFAIP3/XRCC6/OTUD4/FADD/EP300/NFKBIA/HSP90B1/PGLYRP1/IRF1/BCL10/LTF/SFPQ/LILRA4/PSMD7/PSMB5/IFI16/UBA52/ITCH/TNIP1/GPATCH3/MATR3/CREBBP/RAF1/IRF4/BTK/TRAF6/PQBP1/IFIH1/CYLD/MAP3K1/RELA/TSPAN6/PSMB7/RAB7B/CNPY3/CD300LF/PSMD1/MUC2/PSMD9/UBC/UBE2D3/RNF125/COLEC12/PAK3/TLR9/NONO/CD300A/CAV1/LYN/MUC3A/PSME1/RPS6KA5/TRIL/NR1H4/RSAD2/ALPK1/SIN3A/CUL1/ZCCHC3	65
BP	GO:0050821	protein stabilization	41/2486	178/18670	0.0002673	0.006962	0.005456	CLU/COG3/DNLZ/EP300/SMAD7/ATP1B2/NAA16/PINK1/PHB2/AHSP/CREB1/FBXW7/STXBP1/HSP90AA1/TELO2/USP7/MDM4/SEC16A/IGF1/GPIHBP1/STK4/SMO/CCT8/HCFC1/CAMLG/ANK2/PDCD10/USP33/FLNA/MSX1/HSP90AB1/RPS7/TAF1/WFS1/PFN1/CRYAB/NAA15/PIN1/NAPG/TRIM44/RASSF2	41
BP	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress	15/2486	43/18670	0.0002699	0.007	0.005487	NOL3/SFPQ/PINK1/FBXW7/STK24/SIRT1/NME5/HSPB1/PML/MAP3K5/MELK/MCL1/DIABLO/PDCD10/NONO	15
BP	GO:0031667	response to nutrient levels	94/2486	499/18670	0.0002741	0.007065	0.005537	SIRT2/RRAGA/PMAIP1/GABARAPL2/MAP1LC3A/PPARG/SPARC/ARG1/DEPDC5/BCL11A/HSP90B1/EIF2AK4/JUN/BCL10/LPL/GHRL/HAT1/SCT/FSTL1/TGFB1/SSH1/IGFBP2/C2/LCN2/SORL1/PPM1D/CREB1/KANK2/ZFP36/IFI16/CACNB3/GAS6/EIF2S1/CYP26B1/CCND1/STK24/LARP1/P2RY12/ZC3H12A/ALPL/SIRT1/SESN2/SPP1/PHEX/MAX/DDIT3/EGFR/TRIM24/HSD11B2/EIF2A/SFRP2/STC1/P2RX7/ULK2/TBL2/MAP3K5/RELA/ADIPOR2/CADPS2/PTN/ASS1/NENF/CBL/P2RY2/KLF10/LRP11/SESN3/FOXK2/BMP8A/CIB2/IL1B/CPS1/FKBP1B/SFRP1/ALDH1A2/CDKN2B/FAM107A/USP33/HMGCS1/STC2/MTOR/POSTN/ADCYAP1/ITGA2/TAF1/HSPA5/PDK4/TNC/MGMT/NR1H4/NQO1/MTHFR/HMGCL/NCOA1	94
BP	GO:1904018	positive regulation of vasculature development	50/2486	230/18670	0.0002747	0.007065	0.005537	ANXA3/CHI3L1/DDAH1/PDPK1/PRKCB/TWIST1/FLT1/GHRL/VEGFC/HIPK1/NRP1/CX3CL1/MIR21/SMAD1/ZC3H12A/FGF18/RAPGEF3/ANGPTL4/SIRT1/JUP/ECM1/NOS3/JAK1/HSPB1/SFRP2/SMOC2/RAMP2/RHOJ/PAK4/CEACAM1/SRPX2/AGTR1/EFNB2/AQP1/KLF4/APLNR/TIE1/CD34/NOTCH1/IL1B/TEK/HSPB6/ANGPT2/ITGB8/WNT5A/CDH5/MAP3K3/KDR/HYAL1/CCBE1	50
BP	GO:0007409	axonogenesis	89/2486	468/18670	0.0002843	0.007283	0.005708	GRB10/NRCAM/SCN1B/CTTN/FGF13/PTPRO/ITGA4/SEMA3B/BDNF/TRAK1/RNF6/PLXNA3/PARD3/AGRN/RND2/CREB1/SEMA3G/NEXN/NRP1/L1CAM/ADARB1/STXBP1/RAPH1/BOC/HSP90AA1/NEFH/FN1/NFIB/CRMP1/YTHDF1/SPP1/NTRK2/SEMA4D/UCHL1/SKIL/ULK2/CXCL12/SEMA6D/SEMA5B/EPHB4/FLRT2/CHN1/NIN/IRS2/MAP2/ROBO4/PIK3CD/EFNB2/SMO/POU4F1/FRS2/ENAH/GAP43/NOTCH1/SHOX2/DCLK1/TSKU/GLI3/PLXNA1/MATN2/THY1/GPC1/PPP3CB/CDK5R1/WNT5A/PAK3/USP33/NDN/NR4A2/IGSF9/HSP90AB1/SLIT2/NTN4/MYH10/SEMA3E/RAB8A/RPS6KA5/SLIT1/MYCBP2/DOK5/ETV1/EPHB2/GFRA1/SIN3A/PARD6B/CDH11/SHANK3/GDI1/DOK4	89
BP	GO:0060759	regulation of response to cytokine stimulus	43/2486	190/18670	0.0002889	0.007372	0.005778	SH2B3/TNFAIP3/OTUD4/FADD/PPARG/CASP4/ARG1/CLIP3/SPATA2/CSF1/TRIM6/TNF/YTHDF2/NOL3/IL1R1/DHX9/HIPK1/PXDN/SAMHD1/GAS6/MIR21/PARP9/ECM1/IFIH1/CYLD/JAK1/CCDC3/LIFR/KLF4/CD300LF/TREM2/WNT5A/YTHDF3/CNOT7/HSP90AB1/CAV1/SLIT2/MADD/PTPRC/NR1H4/ABCE1/AXL/TRIM44	43
BP	GO:0002791	regulation of peptide secretion	94/2486	500/18670	0.0002944	0.007441	0.005832	SRI/LRP5L/ORM1/SYTL4/MMP8/ITPR1/TNFAIP3/ARG2/MBP/CDK16/ARF1/MAPK11/TRIM6/SLC25A5/CACNA2D2/TNF/TWIST1/LPL/GHRL/TGFB2/SCT/FRMD4A/VEGFC/DHX9/CD244/TGFB1/SERP1/TRH/RAB11FIP1/PFKFB2/RAB11FIP5/C2CD2L/GAS6/RHBDD3/ICA1/FCGR2B/ADRA2A/PPID/ERP29/GJA5/CX3CL1/PAM/ZC3H12A/FN1/RAPGEF3/PTGER4/JAGN1/TRAF6/TM7SF3/EGFR/IFIH1/P2RX7/PML/IGF1/SLC25A6/RHBDF1/IRS2/KCNA5/IL2/TNFRSF14/BMP8A/CD34/IL1B/STX4/FKBP1B/SFRP1/IL33/TREM2/PPP3CB/PSMD9/FZD5/SSC5D/NLRP1/REST/WNT5A/TLR9/IL26/PARD6A/CAPN10/LYN/POSTN/ADCYAP1/KCNS3/FRMD8/MYH10/MIDN/UNC13B/NR1H4/RSAD2/LRP5/RAPGEF4/SYT11/ABAT/NLRP7	94
BP	GO:0021700	developmental maturation	59/2486	284/18670	0.0002966	0.007441	0.005832	C1QA/SIRT2/NRCAM/EPB42/EDNRB/GLDN/PPARG/CABYR/LHX6/BCL11A/SNX19/L3MBTL3/YTHDF2/TRIM58/LTF/TGFB2/TAL1/AGRN/HES1/CDKN1C/STXBP1/CX3CL1/BMP2/ZBTB7A/BTK/NFATC4/DDIT3/NOM1/SEMA4D/IGF1/CATSPER3/YWHAZ/PTH1R/SCLT1/SLC26A6/LGI4/RND1/THBS3/BFSP1/NSUN2/CCL21/RXFP2/ALDH1A2/FZD5/CDK5R1/WNT5A/POU2F2/NR4A2/SLC26A8/CDH5/NTN4/MTOR/IGSF21/PFN1/UNC13B/DEFB1/ARHGEF15/AXL/KIF14	59
BP	GO:0045862	positive regulation of proteolysis	72/2486	363/18670	0.0002998	0.007441	0.005832	CLU/SIRT2/PSMD14/PMAIP1/CRADD/MBP/KEAP1/FADD/PPARG/TBC1D10A/EDEM1/CASP4/RPS27L/SNCA/TNF/SMAD7/BCL10/PCOLCE2/PINK1/IFI16/ARIH2/HERPUD1/TNIP1/FBXW7/ADRA2A/MIR21/ZC3H12A/FN1/DAB2/SIRT1/ASPH/ECSCR/SFRP2/PML/MAP3K5/CBFA2T3/ZFAND2A/PCOLCE/EGF/VCP/CSNK1A1/PRR7/RCHY1/PLK3/PLK1/NUPR1/DIABLO/MYH9/IL1B/IL33/TREM2/NLRP1/REST/PPM1F/FBLN1/RNF139/RNF19B/CHFR/ARIH1/CAV1/LYN/DLC1/BAK1/TAF1/PDCD5/PSME1/SPON1/ANP32B/SH3D19/CLEC3B/CCBE1/CIDEB	72
BP	GO:0001649	osteoblast differentiation	49/2486	225/18670	0.0003009	0.007441	0.005832	LRP5L/ACVR1/JUND/MEF2D/COL6A1/TMEM119/TNF/TWIST1/LTF/DHX9/RPS15/TWSG1/MIR21/SMAD1/BMP2/ALPL/DDX21/RSL1D1/MRC2/FBN2/SPP1/WWTR1/TWIST2/LOX/SFRP2/SEMA4D/NPNT/ACVR2A/IGF1/SATB2/PTH1R/IGFBP5/SMO/CREB3L1/SMOC1/NOTCH1/SHOX2/GLI3/CTHRC1/SFRP1/GPNMB/REST/RBMX/DDR2/TNC/JUNB/LRP5/IGFBP3/RASSF2	49
BP	GO:0048736	appendage development	41/2486	179/18670	0.0003029	0.007441	0.005832	MBNL1/NIPBL/TBX5/PBX1/TWIST1/TGFB2/B9D1/PBX2/CYP26B1/GJA5/CREBBP/PAM/WDR19/FBN2/LMBR1/ASPH/SFRP2/HOXC10/WNT9A/NR2F2/HOXA10/PRRX1/MEOX2/IFT140/SOX9/TBX2/SMOC1/NOTCH1/SHOX2/GLI3/HOXA11/C2CD3/ALDH1A2/WNT5A/MSX1/PKDCC/HOXA9/BAK1/INTU/TMEM231/HOXD9	41
BP	GO:0048771	tissue remodeling	41/2486	179/18670	0.0003029	0.007441	0.005832	ITGB3/LRP5L/INPP5D/TNFAIP3/ARG1/LIPA/TMEM119/NOL3/TGFB1/ACE/GJA5/FOXC1/SPP1/THBS4/TRAF6/EGFR/NOS3/P2RX7/PTN/PTH1R/TNFRSF11A/CEACAM1/BGN/IGFBP5/IL2/RSPO3/ACP5/NOTCH2/CTHRC1/SFRP1/GPNMB/NOX4/MIR214/CAV1/CSPG4/BAK1/PDK4/HOXA3/LRP5/AXL/RASSF2	41
BP	GO:0060173	limb development	41/2486	179/18670	0.0003029	0.007441	0.005832	MBNL1/NIPBL/TBX5/PBX1/TWIST1/TGFB2/B9D1/PBX2/CYP26B1/GJA5/CREBBP/PAM/WDR19/FBN2/LMBR1/ASPH/SFRP2/HOXC10/WNT9A/NR2F2/HOXA10/PRRX1/MEOX2/IFT140/SOX9/TBX2/SMOC1/NOTCH1/SHOX2/GLI3/HOXA11/C2CD3/ALDH1A2/WNT5A/MSX1/PKDCC/HOXA9/BAK1/INTU/TMEM231/HOXD9	41
BP	GO:0071347	cellular response to interleukin-1	41/2486	179/18670	0.0003029	0.007441	0.005832	CHI3L1/PSMD14/PSMD12/OTUD4/YY1/NFKBIA/MAPK11/SQSTM1/USP10/IL1R1/PSMD7/PSMB5/LCN2/UBA52/CX3CL1/ZC3H12A/TRAF6/CCL13/RELA/PLCB1/TFPI/PSMB7/HAS2/SOX9/IL1B/PSMD1/CCL21/SFRP1/PSMD9/UBC/RBMX/CCL8/MAP3K3/PSME1/RPS6KA5/RC3H1/ADAMTS12/CCL18/HYAL1/CUL1/NLRP7	41
BP	GO:0032835	glomerulus development	19/2486	62/18670	0.0003036	0.007441	0.005832	PTPRO/HEYL/HES1/FOXC1/GPR4/WWTR1/MTSS1/PDGFRA/SULF1/PDGFRB/CD34/NOTCH1/TEK/ANGPT2/MAGI2/PODXL/ACTA2/ENPEP/NOTCH3	19
BP	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	19/2486	62/18670	0.0003036	0.007441	0.005832	PMAIP1/PPP1R15A/ITPR1/CASP4/HYOU1/HERPUD1/ERN1/ERP29/DNAJC10/RNF183/SIRT1/DDIT3/BCL2L1/PML/MAP3K5/SERINC3/CREB3L1/BAK1/WFS1	19
BP	GO:0003002	regionalization	70/2486	351/18670	0.0003066	0.007484	0.005866	C1QA/LRP5L/TRA2B/ACVR1/HOXB5/YY1/IRX2/EP300/HEYL/PBX1/BHLHE41/HOXA7/CRKL/LDB1/PBX2/BHLHE40/SPRY1/HIPK1/HES6/HES1/MEOX1/NRP1/PCSK6/CYP26B1/FOXC1/BMP2/IRX3/WDR19/DDIT3/SFRP2/DMRT3/ACVR2A/HOXC10/HOXC6/SIX1/HOXB7/HOXD8/NR2F2/HOXA10/CDON/SMO/FRS2/MEOX2/IFT140/GREM2/NOTCH1/GLI3/HOXA11/HOXC9/BTG2/SFRP1/ALDH1A2/FZD5/BPTF/FKBP8/WNT5A/MSX1/EMX2/TBX1/SSBP3/PCGF2/SIX2/HOXA9/INTU/PALB2/HOXC5/ARC/HOXA3/LRP5/HOXD9	70
BP	GO:0043200	response to amino acid	29/2486	113/18670	0.0003093	0.007502	0.005879	RRAGA/TOMM20/ARG1/COL6A1/BCL11A/TNF/CDO1/CREB1/COL16A1/SESN2/EGFR/BCL2L1/NTRK2/RELA/PTN/ASS1/SIX1/COL4A1/PDGFRA/SESN3/CPEB1/CPS1/IPO5/MTOR/LYN/GLRB/COL5A2/MTHFR/COL1A2	29
BP	GO:0002711	positive regulation of T cell mediated immunity	16/2486	48/18670	0.0003097	0.007502	0.005879	FAM49B/CD1C/FADD/IL1R1/FBXO38/CD1B/TRAF6/IL23R/P2RX7/HLA-B/IL12A/IL1B/FZD5/PTPRC/RSAD2/HLA-A	16
BP	GO:0009266	response to temperature stimulus	52/2486	243/18670	0.0003144	0.007582	0.005942	IER5/GMPR/CAMK2G/PPARG/BAG4/EP300/NFKBIA/EIF2AK4/LPL/DNAJA1/NUP93/FKBP4/TRH/EIF2S1/RBM3/HSP90AA1/CREBBP/HSF4/NUP50/FOS/ARPP21/SIRT1/STAC/NOS3/IGF1/CXCL12/NUP153/NUP210/VCP/SLC25A27/RAE1/NUP188/NUP160/TGFB1I1/NUP54/DNAJA4/LRP11/NUP214/NUP155/CD34/NR2F6/HSP90AB1/MTOR/LYN/DNAJA2/HSPA5/POLR2D/CRYAB/HSPB8/LXN/HSPA9/EIF2B2	52
BP	GO:0090085	regulation of protein deubiquitination	7/2486	12/18670	0.0003155	0.007582	0.005942	OTUD4/TRIM21/ITCH/TNIP1/UBXN1/ZC3H12A/VCP	7
BP	GO:0045926	negative regulation of growth	53/2486	249/18670	0.0003177	0.007607	0.005962	FGF13/SERTAD2/PPARG/YY1/SEMA3B/INHBA/RNF6/MAPK11/PLXNA3/BCL11A/TBX5/DUSP10/FXN/PPP2CA/TGFB2/TGFB1/SERTAD3/SEMA3G/NRP1/CDKN2C/FLCN/MT2A/SIRT1/SESN2/SPP1/SFRP2/SEMA4D/PML/WFDC1/ULK2/ADIPOR2/SEMA6D/SEMA5B/MIR17HG/MAP2/STK4/IGFBP5/NOTCH1/NOTCH2/JARID2/SFRP1/CRLF3/CDK5R1/WNT5A/MSX1/SLIT2/STC2/SEMA3E/CRYAB/RERG/HYAL1/OSGIN2/ING5	53
BP	GO:0045732	positive regulation of protein catabolic process	47/2486	214/18670	0.000323	0.007691	0.006028	CLU/SIRT2/MYLIP/TNFAIP3/KEAP1/EDEM1/APC/TNF/SMAD7/SORL1/ARIH2/HERPUD1/RHBDD3/ITCH/TIPARP/FBXW7/ADRA2A/HSP90AA1/DAB2/ECSCR/HECW2/CBFA2T3/ZFAND2A/MSN/EGF/VCP/ATG4B/CSNK1A1/RCHY1/PLK3/IDE/PLK1/NUPR1/SOX9/IL1B/IL33/TREM2/WNT5A/RNF139/RNF19B/CHFR/ARIH1/CAV1/TAF1/BARD1/SH3D19/LPCAT1	47
BP	GO:0030509	BMP signaling pathway	37/2486	157/18670	0.0003237	0.007691	0.006028	ACVR1/PELO/HTRA1/RGMA/USP9Y/SMAD7/FSTL1/SORL1/HES1/RBPMS2/PCSK6/TWSG1/MIR21/SMPD3/SMAD1/BMP2/HTRA3/SFRP2/ACVR2A/SKIL/ITGA3/SULF1/SFRP4/PPM1A/GREM2/BMP8A/NOTCH1/SFRP1/ZNF423/UBE2D3/FKBP8/WNT5A/MSX1/RYR2/CDH5/FBN1/CHRDL1	37
BP	GO:0006979	response to oxidative stress	86/2486	451/18670	0.0003258	0.007693	0.00603	HBB/SIRT2/NUDT15/MAP1LC3A/PPP1R15B/TNFAIP3/ARG1/STX2/SNCA/TNF/JUN/FXN/NOL3/SFPQ/PINK1/HNRNPM/TPM1/PSMB5/LCN2/PRDX2/CYGB/KDM6B/PXDN/EIF2S1/FBXW7/MSRB3/STK24/MIR21/SMPD3/ETFDH/ZC3H12A/SCARA3/CLN8/FOS/BTK/PYCR1/SIRT1/SESN2/GCH1/EGFR/NME5/NOS3/HSPB1/PML/MAP3K5/RELA/LIAS/HP/MMP3/PDGFRA/MMP9/KCNA5/SESN3/MELK/PLK3/AQP1/KLF4/MCL1/PDGFRB/GPX8/DIABLO/STX4/FKBP1B/RBPMS/PDCD10/REST/NOX4/NONO/NR4A2/DUSP1/PCGF2/STC2/BAK1/RGS14/C19orf12/SOD3/KPNA4/MAPKAP1/STAU1/MGMT/CRYAB/HYAL1/SIN3A/AXL/NQO1/CPEB2	86
BP	GO:0010632	regulation of epithelial cell migration	60/2486	291/18670	0.0003263	0.007693	0.00603	ITGB3/ANXA3/PDPK1/PPARG/SPARC/JUN/DUSP10/TGFB2/VEGFC/TGFB1/NRP1/CLASP2/FBXW7/MIR21/ZC3H12A/FGF18/CAPN7/MMRN2/SIRT1/JUP/NOS3/HSPB1/STC1/SMOC2/ADAMTS9/ITGA3/CARD10/VASH1/PTN/RHOJ/CEACAM1/MMP9/NR2F2/DNAJA4/SRPX2/MEOX2/BCAR1/KLF4/EMP2/HAS2/SOX9/NOTCH1/TEK/PTPRG/ANGPT2/ENPP2/PDCD10/PPM1F/RREB1/WNT5A/DCN/MAP3K3/SLIT2/MTOR/CLASP1/KDR/ITGA2/PFN1/HYAL1/CCBE1	60
BP	GO:0021955	central nervous system neuron axonogenesis	13/2486	35/18670	0.0003386	0.007953	0.006233	SCN1B/ADARB1/HSP90AA1/NFIB/NIN/DCLK1/TSKU/NR4A2/HSP90AB1/SLIT2/MYCBP2/EPHB2/CDH11	13
BP	GO:0007229	integrin-mediated signaling pathway	27/2486	103/18670	0.0003406	0.007953	0.006233	ITGB3/ITGB5/CD177/ITGA4/LIMS2/PHACTR4/NRP1/ITGA7/COL16A1/VAV1/ITGA9/ITGA3/PTN/CEACAM1/ITGAL/FERMT2/BCAR1/EMP2/MYH9/NEDD9/THY1/LIMS1/ITGB8/VAV3/FLNA/ITGBL1/ITGA2	27
BP	GO:0031214	biomineral tissue development	38/2486	163/18670	0.0003411	0.007953	0.006233	FAM20A/CNNM4/ACVR1/GATA1/BCOR/TMEM119/TWIST1/LTF/TGFB1/GAS6/SLC20A1/SMPD3/BMP2/ALPL/FBN2/SPP1/PHEX/ECM1/LOX/NOS3/P2RX7/ACVR2A/IGF1/PTN/PTH1R/KLF10/SOX9/NOTCH1/ANKH/ASPN/GPNMB/DDR2/TBX1/PKDCC/KL/MGP/CLEC3B/COL1A2	38
BP	GO:0046578	regulation of Ras protein signal transduction	51/2486	238/18670	0.0003451	0.007985	0.006258	SPRY2/EPS8/SCAI/CSF1/SQSTM1/ARHGEF37/ARFGEF2/TGFB2/CRKL/LPAR6/SPRY1/KANK2/PSD3/AKAP13/NRP1/FLCN/RAF1/GPR4/ARHGEF7/FGD5/VAV1/LPAR4/SPRY4/GPR35/IGF1/ITGA3/PLEKHG5/ITSN2/CBL/IRS2/FARP1/PDGFRB/NOTCH1/NOTCH2/ARHGEF16/DENND4B/VAV3/FGD3/P2RY8/SOS2/MADD/LYN/DLC1/TNFAIP1/MAPKAP1/ARHGEF12/EPHB2/ARHGEF15/FBXO8/KIF14/EPS8L1	51
BP	GO:0051607	defense response to virus	51/2486	238/18670	0.0003451	0.007985	0.006258	IFI27/PMAIP1/TNFAIP3/FADD/HTRA1/TRIM6/LYST/EIF2AK4/IRF1/DHX9/IFITM3/IFI16/SAMHD1/ITCH/ADARB1/GPATCH3/MAP3K14/PARP9/ZC3H12A/DDX21/RTP4/ILF3/PQBP1/IL23R/IFIH1/PML/RELA/TSPAN6/SERINC3/IFIT3/IFIT1/RNF216/IFIT5/IFI6/DTX3L/IFITM2/IL1B/IL33/SKP2/RNF125/FLNA/TLR9/CNOT7/PCBP2/PTPRC/RSAD2/ABCE1/SETD2/SIN3A/ZCCHC3/TRIM44	51
BP	GO:0060562	epithelial tube morphogenesis	65/2486	322/18670	0.0003498	0.008065	0.006321	LRP5L/SPRY2/ARID1A/ACVR1/IRX2/CSF1/PBX1/TNF/TWIST1/DLG1/BCL10/TGFB2/TGFB1/PHB2/SPRY1/PHACTR4/HES1/NRP1/MIR21/BMP2/LUZP1/IRX3/NFATC4/TRAF6/SFRP2/PML/NPNT/MTSS1/LIAS/EGF/SIX1/COL4A1/HOXB7/STK4/EFNB2/SEC24B/SMO/SOX9/TBX2/NOTCH1/YAP1/GLI3/HOXA11/CTHRC1/SFRP1/C2CD3/WNT5A/ADAMTS16/RYR2/PODXL/TBX1/SIX2/SLIT2/GZF1/RPS7/DLC1/SEMA3E/PFN1/TNC/SPINT2/ADAMTS12/LRP5/SETD2/MTHFR/LZTS2	65
BP	GO:0030038	contractile actin filament bundle assembly	26/2486	98/18670	0.0003549	0.008123	0.006367	ITGB5/ARHGAP6/BAG4/WASF2/TPM1/NRP1/CLASP2/ASAP3/MIR21/RAPGEF3/PTGER4/ELN/PHLDB2/ARHGAP28/SFRP1/SORBS1/NOX4/PPM1F/MTOR/CLASP1/DLC1/TNFAIP1/PFN1/FHDC1/ARHGEF15/LIMCH1	26
BP	GO:0043149	stress fiber assembly	26/2486	98/18670	0.0003549	0.008123	0.006367	ITGB5/ARHGAP6/BAG4/WASF2/TPM1/NRP1/CLASP2/ASAP3/MIR21/RAPGEF3/PTGER4/ELN/PHLDB2/ARHGAP28/SFRP1/SORBS1/NOX4/PPM1F/MTOR/CLASP1/DLC1/TNFAIP1/PFN1/FHDC1/ARHGEF15/LIMCH1	26
BP	GO:0030282	bone mineralization	29/2486	114/18670	0.0003629	0.008275	0.006486	ACVR1/GATA1/BCOR/TMEM119/TWIST1/LTF/TGFB1/SMPD3/BMP2/FBN2/PHEX/ECM1/LOX/P2RX7/ACVR2A/IGF1/PTN/PTH1R/KLF10/SOX9/ANKH/ASPN/GPNMB/DDR2/PKDCC/KL/MGP/CLEC3B/COL1A2	29
BP	GO:0009954	proximal/distal pattern formation	12/2486	31/18670	0.000366	0.008316	0.006518	IRX2/PBX1/PBX2/CYP26B1/IRX3/HOXC10/HOXA10/GLI3/HOXA11/ALDH1A2/HOXA9/HOXD9	12
BP	GO:0048704	embryonic skeletal system morphogenesis	25/2486	93/18670	0.0003679	0.008329	0.006528	HOXB5/NIPBL/TWIST1/DLG1/HOXA7/WDR19/SATB2/SIX1/HOXB7/PDGFRA/WNT9A/PRRX1/IFT140/SHOX2/GLI3/HOXA11/HOXC9/TBX15/TBX1/PCGF2/SIX2/HOXA3/SETD2/HYAL1/HOXD9	25
BP	GO:1901888	regulation of cell junction assembly	24/2486	88/18670	0.000379	0.008537	0.006691	ARHGAP6/CLDN5/TNF/LDB1/NRP1/ACE/CLASP2/COL16A1/NPHP1/PHLDB2/MYO1C/TEK/SFRP1/THY1/FZD5/LIMS1/PPM1F/FAM107A/TJP1/CAV1/CLASP1/DLC1/KDR/LIMCH1	24
BP	GO:0061437	renal system vasculature development	11/2486	27/18670	0.0003812	0.008537	0.006691	HES1/NRP1/GPR4/PDGFRA/PDGFRB/CD34/NOTCH1/TEK/ANGPT2/ACTA2/NOTCH3	11
BP	GO:0061440	kidney vasculature development	11/2486	27/18670	0.0003812	0.008537	0.006691	HES1/NRP1/GPR4/PDGFRA/PDGFRB/CD34/NOTCH1/TEK/ANGPT2/ACTA2/NOTCH3	11
BP	GO:0072009	nephron epithelium development	28/2486	109/18670	0.0003829	0.008544	0.006696	PTPRO/IRX2/HEYL/PBX1/DLG1/TGFB1/HES1/FOXC1/BMP2/IRX3/WWTR1/NPNT/MTSS1/SIX1/HOXB7/SMO/SOX9/CD34/NOTCH1/YAP1/GLI3/HOXA11/ADAMTS16/MAGI2/PODXL/SIX2/GZF1/LZTS2	28
BP	GO:0006473	protein acetylation	45/2486	204/18670	0.0003866	0.008591	0.006734	MUC1/PHF20/NCOA3/POLE3/MSL2/EP300/SNCA/TAF10/TWIST1/HAT1/NAA16/YEATS2/TGFB1/LDB1/ING3/NAA30/WDR5/FLCN/CREBBP/IRF4/TRRAP/GTF3C4/RAPGEF3/SIRT1/SETD5/NAT9/RSF1/MORF4L2/HCFC1/NUPR1/MCM3AP/IL1B/NAA25/EP400/CHD5/PCGF2/SET/TAF1/RPS6KA5/EPC1/PER1/SIN3A/NAA15/NCOA1/ING5	45
BP	GO:1901342	regulation of vasculature development	81/2486	422/18670	0.0003878	0.008591	0.006734	ANXA3/SPRY2/CHI3L1/DDAH1/PDPK1/TNFAIP3/PPARG/SPARC/GTF2I/PRKCB/TWIST1/FLT1/GHRL/TGFB2/VEGFC/HIPK1/NRP1/FBXW7/CX3CL1/MIR21/SMAD1/ZC3H12A/FOXC1/FGF18/RAPGEF3/GPR4/ANGPTL4/MMRN2/SIRT1/THBS4/JUP/ECM1/NOS3/JAK1/ECSCR/HSPB1/SFRP2/PML/SMOC2/ADAMTS9/CARD10/VASH1/PTN/RAMP2/RHOJ/COL4A2/PAK4/CEACAM1/SRPX2/AGTR1/SULF1/EFNB2/AQP1/MEOX2/KLF4/APLNR/EMP2/CREB3L1/TIE1/CD34/NOTCH1/IL1B/TEK/SFRP1/HSPB6/ANGPT2/ENPP2/GPNMB/PDCD10/ITGB8/WNT5A/MIR214/DCN/CDH5/MAP3K3/KDR/SEMA3E/FOXJ2/HYAL1/NFATC3/CCBE1	81
BP	GO:0035924	cellular response to vascular endothelial growth factor stimulus	20/2486	68/18670	0.0003905	0.008621	0.006757	SPRY2/FLT1/GAS1/VEGFC/PTP4A3/NRP1/ERN1/FOXC1/HSPB1/SMOC2/RELA/RAMP2/PDGFRA/PDGFRB/MYO1C/NOTCH1/DCN/KDR/ADAMTS12/CCBE1	20
BP	GO:0021954	central nervous system neuron development	22/2486	78/18670	0.0003929	0.008632	0.006766	SCN1B/LHX6/PLXNA3/CRKL/NRP1/ADARB1/HSP90AA1/NFIB/NTRK2/NIN/MAP2/DCLK1/TSKU/BTG2/WNT5A/NR4A2/HSP90AB1/SLIT2/MYCBP2/EPHB2/CDH11/LHX8	22
BP	GO:0050688	regulation of defense response to virus	21/2486	73/18670	0.0003941	0.008632	0.006766	TNFAIP3/HTRA1/TRIM6/EIF2AK4/DHX9/ITCH/GPATCH3/PARP9/ZC3H12A/PQBP1/IL23R/TSPAN6/IFIT1/RNF216/DTX3L/IL1B/RNF125/PCBP2/SIN3A/ZCCHC3/TRIM44	21
BP	GO:0007163	establishment or maintenance of cell polarity	46/2486	210/18670	0.0003952	0.008632	0.006766	SPRY2/FGF13/SLC9A3R1/MPP5/PARD3/PARD6G/DLG1/CRKL/FRMD4A/RND2/SPRY1/HES1/RHOF/CLASP2/CYP26B1/HSP90AA1/DLG2/MSN/RND3/RHOJ/MAP2/ANK1/RND1/AQP1/FAT1/AMOTL2/PLK1/PDZD11/KIF2C/MYH9/TEK/CCL21/MPP7/WNT5A/NDE1/PARD6A/CDH5/ALPK2/HSP90AB1/CLASP1/SPN/MAPKAP1/SPINT2/DOCK8/PARVA/PARD6B	46
BP	GO:0070997	neuron death	69/2486	348/18670	0.0003999	0.008705	0.006823	CLU/C1QA/NTF3/CIT/PDPK1/FAIM2/POLB/FADD/BDNF/CSF1/SNCA/TNF/JUN/TGFB2/SSH1/PINK1/SORL1/HYOU1/CREB1/NRP1/CRLF1/ADARB1/SRPK2/EIF2S1/FBXW7/STXBP1/FCGR2B/CX3CL1/THRB/FOS/REL/NFATC4/SIRT1/MAX/DDIT3/BCL2L1/NTRK2/MAP3K5/SIX1/SLC25A27/CBL/EFNB2/POU4F1/TRIM2/MCL1/NUPR1/CD34/DIABLO/BTG2/NES/CDK5R1/GPNMB/NLRP1/REST/WNT5A/PAK3/NONO/NR4A2/TP53BP2/HSP90AB1/MTOR/SET/WFS1/HSPA5/CORO1A/AXL/NQO1/KIF14/PIN1	69
BP	GO:1901654	response to ketone	43/2486	193/18670	0.000412	0.008936	0.007004	ADCY3/FOSB/PPARG/ARG1/TGFB2/TGFB1/TRH/CCND1/LARP1/FOS/PTGER4/SIRT1/SPP1/EGFR/BCL2L1/ADCY6/RELA/CATSPER3/MSN/PTN/ASS1/PTGFR/RAMP2/CBL/AKR1C2/AQP1/KLF4/YAP1/CPS1/CCL21/SFRP1/NR3C1/OXTR/NCOA2/DUSP1/AKAP8/CAV1/SLIT2/CDC5L/TNC/SIN3A/FIBIN/NCOA1	43
BP	GO:0043254	regulation of protein complex assembly	88/2486	467/18670	0.000418	0.009035	0.007081	CLU/SIRT2/RHOBTB1/CTTN/PMAIP1/ARHGAP18/EPS8/BCLAF1/HJURP/TMOD1/BAG4/MYADM/NAV3/EP300/ARF1/CLIP3/SNCA/TNF/TWIST1/JUN/DLG1/FBLIM1/MMP1/TGFB1/PINK1/TAL1/FKBP4/SORL1/SELP/CREB1/GTF2H3/STXBP1/HSP90AA1/RAF1/P2RY12/G3BP2/PTGER4/ELN/AVIL/SENP6/COTL1/MSN/VCP/ATXN2L/AP1AR/MMP3/NIN/MAP2/PFN4/LMOD1/ARHGAP28/BMF/PPM1A/SEC24B/WHAMM/WASF1/IDE/MYO1C/HCFC1/CAPZA1/TMSB4Y/FCHSD2/CCL21/MPP7/CDK5R1/NCKAP1/TMSB15A/PAK3/MIR214/ARPC2/CDH5/SLIT2/HCLS1/MTOR/CLASP1/TAF1/KANK3/STYXL1/PFN1/UNC13B/CDC42EP5/CRYAB/STXBP6/CORO1A/PRRT2/MAGEL2/KIF14/CNOT1	88
BP	GO:0048562	embryonic organ morphogenesis	59/2486	288/18670	0.0004328	0.009323	0.007307	SPRY2/ARID1A/ACVR1/SLC9A3R1/HOXB5/NIPBL/TWIST1/FOXI1/DLG1/HOXA7/PHACTR4/HIPK1/HES1/RBPMS2/HLX/WDR19/FBN2/SP3/SOBP/SATB2/SIX1/HOXB7/PDGFRA/GJB6/WNT9A/SEC24B/SMO/PRRX1/FRS2/MFAP2/IFT140/SOX9/TBX2/NOTCH1/SHOX2/YAP1/ALDH1A3/GLI3/HOXA11/CTHRC1/HOXC9/C2CD3/TBX15/FZD5/WNT5A/EFEMP1/MSX1/LRIG3/RYR2/TBX1/PCGF2/SIX2/FBN1/EPHB2/HOXA3/SETD2/HYAL1/HOXD9/MYO15A	59
BP	GO:1901216	positive regulation of neuron death	25/2486	94/18670	0.0004388	0.009419	0.007382	CLU/C1QA/SNCA/TNF/JUN/TGFB2/SSH1/SRPK2/EIF2S1/FBXW7/FCGR2B/FOS/DDIT3/MAP3K5/EFNB2/MCL1/NUPR1/CDK5R1/REST/WNT5A/PAK3/TP53BP2/MTOR/NQO1/PIN1	25
BP	GO:0043900	regulation of multi-organism process	78/2486	405/18670	0.000443	0.009476	0.007427	SIRT2/IFI27/SLPI/STOM/TNFAIP3/EDNRB/ARG2/HTRA1/ARG1/INHBA/EP300/PPP2R3C/TRIM6/EIF2AK4/PGLYRP1/CAV2/TNF/JUN/YTHDF2/LTF/DHX9/IFITM3/CDK9/PRDX2/TRIM21/ZFP36/IFI16/ITCH/TNIP1/ADARB1/SRPK2/GPATCH3/STXBP1/PPID/LARP1/CHD1/CX3CL1/PARP9/ZC3H12A/ILF3/TRAF6/PQBP1/IL23R/P2RX7/PML/IGF1/POLR2G/TSPAN6/CXCL6/PLCB1/VPS37B/RSF1/IFIT1/RNF216/IFIT5/NOTCH1/LRSAM1/DTX3L/IFITM2/IL1B/RNF125/OXTR/PKN2/REST/CCL8/CNOT7/HPGDS/CAV1/PCBP2/UNC13B/POLR2D/STAU1/RSAD2/SIN3A/SYT11/NR5A2/ZCCHC3/TRIM44	78
BP	GO:0043393	regulation of protein binding	47/2486	217/18670	0.0004491	0.009541	0.007478	SLPI/GAS8/ITGA4/EP300/BDNF/PPP2CA/SPPL3/TDG/SORL1/TRAF4/NRP1/ACE/EIF2S1/BMP2/CRMP1/NFATC4/DAB2/DDX11/LOX/CYLD/DERL1/CFHR2/MFNG/PTPRF/MMP9/MAP2/STK4/TTBK2/IFIT1/CDON/PLK1/GREM2/DTX3L/CTHRC1/NES/WNT5A/USP33/DZIP1/HSP90AB1/CAV1/BAK1/TAF1/GPSM1/SPON1/HSPA5/HOXA3/PIN1	47
BP	GO:0050920	regulation of chemotaxis	47/2486	217/18670	0.0004491	0.009541	0.007478	SUCNR1/NTF3/PTPRO/SEMA3B/PLXNA3/CSF1/VEGFC/AKIRIN1/TGFB1/ELANE/SEMA3G/NRP1/GAS6/P2RY12/FGF18/YTHDF1/EDN3/THBS4/HSPB1/RARRES2/SEMA4D/SMOC2/CXCL12/DAPK2/MTUS1/SEMA6D/SEMA5B/PTN/PDGFRA/IL12A/EFNB2/PDGFRB/NOTCH1/STX4/CCL21/TREM2/ANGPT2/PPM1F/WNT5A/DUSP1/SLIT2/LYN/KDR/ITGA2/MST1/SEMA3E/MYCBP2	47
BP	GO:0003205	cardiac chamber development	39/2486	171/18670	0.0004588	0.009705	0.007606	LTBP1/ARID1A/ACVR1/HEYL/TBX5/SMAD7/TGFB2/TGFB1/TPM1/PDE2A/HES1/NRP1/GJA5/MATR3/FOXC1/LUZP1/MDM4/NOS3/SFRP2/CPE/UBE4B/MIR17HG/SMO/POU4F1/FRS2/TBX2/NOTCH1/SHOX2/NOTCH2/HECTD1/TEK/ZFPM2/ANK2/WNT5A/RYR2/TBX1/SLIT2/MYH10/PARVA	39
BP	GO:0043388	positive regulation of DNA binding	18/2486	59/18670	0.0004607	0.009705	0.007606	SIRT2/MMP8/PPARG/EP300/TRIM6/NIPBL/TWIST1/TGFB1/HES1/IRF4/FOXC1/TRAF6/IGF1/EGF/MMP9/POU4F1/KLF4/ITGA2	18
BP	GO:0035970	peptidyl-threonine dephosphorylation	8/2486	16/18670	0.0004641	0.009705	0.007606	DUSP10/PPP2CA/PPM1D/PDP1/PPM1A/PPM1F/DUSP1/DUSP18	8
BP	GO:0001704	formation of primary germ layer	30/2486	121/18670	0.000465	0.009705	0.007606	ITGB3/ARID1A/ACVR1/ITGB5/MMP8/ITGA4/INHBA/COL6A1/TAL1/KDM6B/ITGA7/TWSG1/NANOG/SMAD1/FN1/FOXC1/SFRP2/ITGA3/COL4A2/MMP9/KLF4/COL5A1/HOXA11/LAMB1/COL12A1/WNT5A/SIX2/ITGA2/COL5A2/SETD2	30
BP	GO:0003417	growth plate cartilage development	13/2486	36/18670	0.000466	0.009705	0.007606	COCH/COL6A1/SCARA3/STC1/COL27A1/COL14A1/THBS3/MATN2/VIT/COL12A1/COL21A1/VWA1/COL6A2	13
BP	GO:1905897	regulation of response to endoplasmic reticulum stress	23/2486	84/18670	0.0004674	0.009705	0.007606	CLU/PMAIP1/PPP1R15A/PPP1R15B/EDEM1/HYOU1/HERPUD1/FCGR2B/ERN1/ERP29/UBXN1/RNF183/SIRT1/DDIT3/BCL2L1/SERINC3/CREB3L1/NUPR1/UBE2G2/CAV1/BAK1/WFS1/HSPA5	23
BP	GO:0010769	regulation of cell morphogenesis involved in differentiation	61/2486	301/18670	0.0004698	0.009705	0.007606	NRCAM/CTTN/FGF13/PTPRO/MYADM/SEMA3B/OLFM4/BDNF/TRAK1/RNF6/PLXNA3/LIMS2/CRKL/CUX2/RND2/SEMA3G/NRP1/L1CAM/FBXW8/FN1/SDC2/YTHDF1/NFATC4/ARHGEF7/SPP1/NTRK2/SEMA4D/HECW2/OBSL1/SKIL/ULK2/CXCL12/PDPN/SEMA6D/SEMA5B/AP1AR/CHN1/NIN/MAP2/HAS2/SHOX2/PLXNA1/NEDD9/THY1/CDK5R1/LIMS1/FBLN1/RREB1/WNT5A/PAK3/FLNA/ARPC2/SLIT2/POSTN/SEMA3E/ARC/MYCBP2/EPHB2/SIN3A/SHANK3/GDI1	61
BP	GO:0042476	odontogenesis	32/2486	132/18670	0.0004699	0.009705	0.007606	FAM20A/CNNM4/HTRA1/INHBA/BCOR/CSF1/TWIST1/TGFB2/TGFB1/SMPD3/JAG2/PAM/FOXC1/BMP2/ALPL/PHEX/TRAF6/DMRT3/PDGFRA/SMO/AQP1/CD34/DLX3/GLI3/LAMB1/ASPN/MSX1/TBX1/TNC/ROGDI/LHX8/COL1A2	32
BP	GO:0035987	endodermal cell differentiation	15/2486	45/18670	0.0004736	0.009705	0.007606	ITGB5/MMP8/ITGA4/INHBA/COL6A1/ITGA7/NANOG/FN1/COL4A2/MMP9/COL5A1/LAMB1/COL12A1/COL5A2/SETD2	15
BP	GO:0033138	positive regulation of peptidyl-serine phosphorylation	27/2486	105/18670	0.0004742	0.009705	0.007606	SPRY2/ARAF/NTF3/BAG4/TRIM6/SNCA/TNF/TGFB1/PINK1/GAS6/HSP90AA1/RAF1/RAPGEF3/EGFR/NTRK2/SFRP2/STK4/BCAR3/RAMP3/PDCD10/WNT5A/HSP90AB1/CAV1/HCLS1/SH2D3C/TNKS1BP1/MAPKAP1	27
BP	GO:0001959	regulation of cytokine-mediated signaling pathway	40/2486	177/18670	0.0004758	0.009705	0.007606	SH2B3/TNFAIP3/OTUD4/FADD/PPARG/CASP4/ARG1/CLIP3/SPATA2/CSF1/TRIM6/TNF/YTHDF2/NOL3/IL1R1/HIPK1/PXDN/SAMHD1/GAS6/MIR21/PARP9/ECM1/CYLD/JAK1/CCDC3/LIFR/CD300LF/TREM2/WNT5A/YTHDF3/CNOT7/HSP90AB1/CAV1/SLIT2/MADD/PTPRC/NR1H4/ABCE1/AXL/TRIM44	40
BP	GO:0003151	outflow tract morphogenesis	22/2486	79/18670	0.000477	0.009705	0.007606	CLDN5/HEYL/NIPBL/TWIST1/JUN/TGFB2/CRKL/HES1/NRP1/GJA5/FOXC1/ELN/SFRP2/SIX1/MIR17HG/SEC24B/TBX2/NOTCH1/ZFPM2/WNT5A/TBX1/PARVA	22
BP	GO:0003007	heart morphogenesis	54/2486	259/18670	0.0004771	0.009705	0.007606	ACVR1/CLDN5/HEYL/NIPBL/TBX5/TWIST1/SMAD7/JUN/TGFB2/CRKL/TGFB1/TPM1/SPRY1/HES1/NRP1/GJA5/MIR21/FOXC1/BMP2/MDM4/ELN/NOS3/SFRP2/OBSL1/CPE/UBE4B/EPHB4/SIX1/FLRT2/MIR17HG/SEC24B/SMO/POU4F1/HAS2/COL5A1/SOX9/TBX2/NOTCH1/SHOX2/NOTCH2/YAP1/TEK/C2CD3/ALDH1A2/ZFPM2/WNT5A/MSX1/RYR2/ALPK2/TBX1/SLIT2/MTOR/DLC1/PARVA	54
BP	GO:0050771	negative regulation of axonogenesis	20/2486	69/18670	0.000482	0.009746	0.007638	FGF13/PTPRO/SEMA3B/RNF6/PLXNA3/SEMA3G/NRP1/SPP1/SEMA4D/ULK2/SEMA6D/SEMA5B/MAP2/THY1/CDK5R1/WNT5A/SLIT2/SEMA3E/EPHB2/GDI1	20
BP	GO:0031670	cellular response to nutrient	21/2486	74/18670	0.0004822	0.009746	0.007638	PPARG/BCL11A/HSP90B1/LPL/SSH1/KANK2/GAS6/P2RY12/PHEX/TRIM24/P2RX7/PTN/P2RY2/CIB2/SFRP1/CDKN2B/POSTN/TAF1/TNC/NR1H4/NCOA1	21
BP	GO:0021953	central nervous system neuron differentiation	41/2486	183/18670	0.0004913	0.009866	0.007733	SCN1B/FAIM2/HERC1/INHBA/LHX6/PLXNA3/CRKL/TAL1/LDB1/HES1/NRP1/ADARB1/HSP90AA1/CLN8/NFIB/NTRK2/SFRP2/DMRT3/HOXC10/SATB2/AGTPBP1/NIN/MAP2/SMO/POU4F1/DCLK1/TSKU/GLI3/BTG2/SFRP1/WNT5A/NR4A2/HSP90AB1/CHD5/SLIT2/MYCBP2/EPHB2/SIN3A/CDH11/SHANK3/LHX8	41
BP	GO:0061136	regulation of proteasomal protein catabolic process	41/2486	183/18670	0.0004913	0.009866	0.007733	CLU/SIRT2/PSMD14/GABARAPL2/ARAF/NUDT15/KEAP1/EDEM1/SMAD7/PINK1/ARIH2/HERPUD1/FBXW7/UBXN1/SMARCC1/USP7/DAB2/ECSCR/CBFA2T3/RHBDF1/ZFAND2A/VCP/WAC/CSNK1A1/RCHY1/PLK3/PLK1/MTM1/NUPR1/CAMLG/IL33/TREM2/UBE2G2/RNF19B/CHFR/ARIH1/HSP90AB1/CAV1/TAF1/PSME1/GIPC1	41
BP	GO:0014074	response to purine-containing compound	35/2486	149/18670	0.0004935	0.009877	0.007742	JUND/FOSB/PPARG/SPARC/HSP90B1/JUN/CDO1/SSH1/PLA2G5/PDE2A/P2RY12/RAPGEF3/FOS/STC1/P2RX7/RELA/ASS1/P2RY2/IGFBP5/SLC26A6/AQP1/MMP19/CIB2/IL1B/TEK/CPS1/NOX4/RYR2/DUSP1/HMGCS1/TAF1/HSPA5/JUNB/PER1/SLC6A1	35
BP	GO:1900180	regulation of protein localization to nucleus	29/2486	116/18670	0.0004952	0.00988	0.007743	RBM22/TGFB1/RASSF5/NOLC1/FLCN/PARP9/ZC3H12A/FBXO4/SESN2/JUP/CARD10/NUP54/TMEM98/SMO/GLIS2/CCT8/PLK1/DTX3L/DCLK1/GLI3/OTUD7B/IPO5/FLNA/BYSL/DCLK3/HCLS1/SIN3A/LZTS2/PIN1	29
BP	GO:0006475	internal protein amino acid acetylation	38/2486	166/18670	0.0004992	0.009912	0.007768	MUC1/PHF20/NCOA3/POLE3/MSL2/EP300/SNCA/TAF10/TWIST1/HAT1/YEATS2/TGFB1/LDB1/ING3/WDR5/FLCN/CREBBP/IRF4/TRRAP/GTF3C4/SIRT1/SETD5/RSF1/MORF4L2/HCFC1/MCM3AP/IL1B/EP400/CHD5/PCGF2/SET/TAF1/RPS6KA5/EPC1/PER1/SIN3A/NCOA1/ING5	38
BP	GO:0032271	regulation of protein polymerization	47/2486	218/18670	5e-04	0.009912	0.007768	RHOBTB1/CTTN/ARHGAP18/EPS8/TMOD1/BAG4/MYADM/NAV3/ARF1/CLIP3/SNCA/DLG1/PINK1/FKBP4/HSP90AA1/ELN/AVIL/COTL1/AP1AR/NIN/MAP2/PFN4/LMOD1/ARHGAP28/WHAMM/WASF1/MYO1C/CAPZA1/TMSB4Y/FCHSD2/CCL21/CDK5R1/NCKAP1/TMSB15A/PAK3/MIR214/ARPC2/CDH5/SLIT2/HCLS1/MTOR/CLASP1/KANK3/PFN1/CDC42EP5/CORO1A/MAGEL2	47
BP	GO:0070570	regulation of neuron projection regeneration	12/2486	32/18670	0.0005152	0.01018	0.00798	RGMA/RTN4RL1/STK24/SPP1/PTN/PTPRF/LRIG2/PRRX1/KLF4/FKBP1B/THY1/INPP5F	12
BP	GO:0060485	mesenchyme development	57/2486	278/18670	0.0005242	0.01029	0.008069	ACVR1/PEF1/EDNRB/SEMA3B/HEYL/TBX5/TWIST1/SMAD7/PPP2CA/TGFB2/TGFB1/ACTG2/SEMA3G/SPRY1/PHACTR4/HES1/MEOX1/NRP1/CLASP2/NOLC1/MIR21/FN1/FOXC1/BMP2/DAB2/EDN3/MDM4/WWTR1/NOS3/SFRP2/SEMA4D/PDPN/SEMA6D/SEMA5B/SIX1/PHLDB2/TGFB1I1/SMO/PDGFRB/HAS2/SOX9/TBX2/NOTCH1/YAP1/IL1B/SFRP1/ALDH1A2/ZFPM2/WNT5A/MSX1/TBX1/SIX2/MTOR/CLASP1/SEMA3E/ACTA2/TCOF1	57
BP	GO:0006406	mRNA export from nucleus	28/2486	111/18670	0.0005259	0.01029	0.008069	SRRM1/NXF3/EIF5A/NXT1/AKAP8L/YTHDC1/SARNP/NUP93/THOC2/U2AF1L4/DDX19A/NUP50/SLBP/NUP153/U2AF1/NUP210/PABPN1/RAE1/NUP188/NUP160/NUP54/NXF1/NUP214/NUP155/MCM3AP/SMG6/POLR2D/SETD2	28
BP	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus	28/2486	111/18670	0.0005259	0.01029	0.008069	SRRM1/NXF3/EIF5A/NXT1/AKAP8L/YTHDC1/SARNP/NUP93/THOC2/U2AF1L4/DDX19A/NUP50/SLBP/NUP153/U2AF1/NUP210/PABPN1/RAE1/NUP188/NUP160/NUP54/NXF1/NUP214/NUP155/MCM3AP/SMG6/POLR2D/SETD2	28
BP	GO:0045778	positive regulation of ossification	24/2486	90/18670	0.0005425	0.01059	0.008298	ACVR1/JUND/NIPBL/TMEM119/LTF/TGFB2/TGFB1/MIR21/SMAD1/BMP2/FBN2/SFRP2/P2RX7/NPNT/ACVR2A/IGF1/PTN/GLI3/CTHRC1/WNT5A/DDR2/PKDCC/KL/LRP5	24
BP	GO:1902893	regulation of pri-miRNA transcription by RNA polymerase II	14/2486	41/18670	0.0005504	0.01065	0.008346	YY1/JUN/TGFB2/TGFB1/SMAD1/BMP2/NFIB/FOS/NFATC4/RELA/SOX9/KLF5/NR3C1/NFATC3	14
BP	GO:0002691	regulation of cellular extravasation	11/2486	28/18670	0.0005529	0.01065	0.008346	FADD/ITGA4/IL1R1/ELANE/PLVAP/PTGER4/CXCL12/PLCB1/CCL21/THY1/XG	11
BP	GO:1902668	negative regulation of axon guidance	11/2486	28/18670	0.0005529	0.01065	0.008346	PTPRO/SEMA3B/PLXNA3/SEMA3G/NRP1/SEMA4D/SEMA6D/SEMA5B/WNT5A/SLIT2/SEMA3E	11
BP	GO:0043113	receptor clustering	17/2486	55/18670	0.0005551	0.01065	0.008346	ITGA4/DLG1/CRKL/TGFB1/SSH1/AGRN/DLG2/WDR19/PIGR/PTN/ITGAL/THY1/FLNA/MAGI2/SSNA1/GLRB/SHANK3	17
BP	GO:0070830	bicellular tight junction assembly	17/2486	55/18670	0.0005551	0.01065	0.008346	CLDN5/MPP5/APC/PARD3/RAB13/TNF/PARD6G/DLG1/ESAM/RAMP2/NPHP1/MYO1C/MPP7/FZD5/TJP1/PARD6A/PARD6B	17
BP	GO:0048762	mesenchymal cell differentiation	47/2486	219/18670	0.0005559	0.01065	0.008346	ACVR1/PEF1/EDNRB/SEMA3B/HEYL/TBX5/TWIST1/SMAD7/PPP2CA/TGFB2/TGFB1/SEMA3G/SPRY1/PHACTR4/HES1/NRP1/CLASP2/NOLC1/MIR21/FN1/FOXC1/BMP2/DAB2/EDN3/WWTR1/SFRP2/SEMA4D/PDPN/SEMA6D/SEMA5B/PHLDB2/TGFB1I1/SMO/HAS2/SOX9/NOTCH1/IL1B/SFRP1/ALDH1A2/WNT5A/MSX1/TBX1/SIX2/MTOR/CLASP1/SEMA3E/TCOF1	47
BP	GO:0048754	branching morphogenesis of an epithelial tube	35/2486	150/18670	0.0005627	0.01074	0.008421	LRP5L/SPRY2/ACVR1/CSF1/PBX1/TNF/DLG1/TGFB1/PHB2/SPRY1/NRP1/BMP2/NFATC4/SFRP2/PML/NPNT/EGF/SIX1/COL4A1/HOXB7/STK4/SMO/SOX9/NOTCH1/YAP1/GLI3/HOXA11/WNT5A/ADAMTS16/SIX2/SLIT2/GZF1/SEMA3E/TNC/LRP5	35
BP	GO:0016049	cell growth	90/2486	484/18670	0.0005662	0.01078	0.008448	NRCAM/CTTN/FGF13/SERTAD2/PPARG/YY1/ITGA4/KIF26A/SEMA3B/INHBA/SLC25A33/BDNF/RNF6/PLXNA3/BCL11A/EIF2AK4/FXN/PPP2CA/TGFB2/CRKL/TGFB1/SERTAD3/RND2/SEMA3G/ARIH2/AKAP13/NRP1/L1CAM/ITCH/RAPH1/HSP90AA1/CDKN2C/FLCN/FN1/SIRT1/SESN2/SPP1/EGFR/KIAA1109/SFRP2/SEMA4D/PML/KAZALD1/WFDC1/ULK2/IGF1/CXCL12/ADIPOR2/SEMA6D/SEMA5B/ITSN2/IGFBP4/PAK4/CEACAM1/NIN/MAP2/IGFBP5/AGTR1/IL2/WASF1/BCAR1/SOX9/DCLK1/PLXNA1/SFRP1/CRLF3/PPP3CB/CDK5R1/WNT5A/FAM107A/NDN/MSX1/HSP90AB1/SLIT2/MTOR/POSTN/SEMA3E/SLIT1/PRSS2/N6AMT1/CRYAB/LTBP4/RERG/HYAL1/SIN3A/KIF14/IGFBP3/PIN1/OSGIN2/GDI1	90
BP	GO:0046794	transport of virus	18/2486	60/18670	0.0005772	0.01096	0.008586	CAV2/NUP93/UBA52/VPS37A/NUP50/KPNA1/NUP153/NUP210/KPNA3/VPS37B/RAE1/NUP188/NUP160/NUP54/NUP214/NUP155/UBC/CAV1	18
BP	GO:0016311	dephosphorylation	89/2486	478/18670	0.0005803	0.01098	0.008606	SPOCD1/SH2D4A/PPTC7/PTP4A2/DUSP28/PPP1R15A/INPP5D/PPP1R15B/POLB/CAMK2G/PTPRO/BAG4/PPP2R3C/PTPN13/HSP90B1/PTP4A1/TNF/PPM1J/DLG1/DUSP10/PPP2CA/SPPL3/TGFB2/TGFB1/SSH1/PINK1/PFKFB2/PPM1D/PTP4A3/PHACTR4/PCDH11X/PTPRH/THNSL2/PPEF2/CTDSPL/DLG2/CEP192/RCAN2/BMP2/ALPL/PPP2R5E/CCDC8/SEMA4D/NPNT/NT5DC3/PTN/PTPN21/MTMR14/PTPRF/PDP1/PPM1A/TMEM225/FARP1/PDGFRB/MTM1/ACP5/PTPRG/FKBP1B/PPP3CB/PTPN14/PPM1F/SMG6/ELL/RNGTT/MAGI2/DUSP1/CD300A/CDH5/PCIF1/HSP90AB1/CILP/INPP5F/MTOR/DUSP18/PPEF1/DLC1/SET/ITGA2/MTMR7/STYXL1/PPP1R3C/MTMR4/PTPRC/CDKN3/SSH3/PPM1N/PTPRB/IGFBP3/PIN1	89
BP	GO:0006026	aminoglycan catabolic process	19/2486	65/18670	0.0005888	0.01111	0.008706	IDS/CHIT1/PGLYRP1/TGFB1/LYG2/AGRN/SDC2/GPC4/GPC6/BGN/LYVE1/GPC1/DCN/ACAN/OGN/CSPG4/FMOD/PRELP/HYAL1	19
BP	GO:0070831	basement membrane assembly	7/2486	13/18670	0.0006049	0.01138	0.008916	PXDN/CLASP2/RAMP2/PHLDB2/LAMB1/NTN4/CLASP1	7
BP	GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	34/2486	145/18670	0.0006094	0.01139	0.008929	FAM49B/CD1C/TNFAIP3/FADD/PARP3/ARG1/TNF/SMAD7/IL1R1/TGFB1/FBXO38/FCGR2B/MIR21/ZC3H12A/CD1B/NFKBIZ/HLX/BTK/EXOSC3/TRAF6/IL23R/P2RX7/HLA-B/CEACAM1/IL12A/IL2/IL1B/IL33/PPP3CB/FZD5/RC3H1/PTPRC/RSAD2/HLA-A	34
BP	GO:0071901	negative regulation of protein serine/threonine kinase activity	34/2486	145/18670	0.0006094	0.01139	0.008929	SPRY2/SH2B3/TNFAIP3/APC/PRKAR2A/DUSP10/PPP2CA/DNAJA1/SORL1/SPRY1/CDKN1C/IPO7/CDKN2C/SIRT1/HSPB1/SFRP2/SPRY4/UCHL1/PKIB/NR2F2/PLK1/PRKAG2/IL1B/SFRP1/CDKN2B/IPO5/DUSP1/CD300A/CAV1/LYN/DUSP18/RGS14/PRKAR2B/LRP5	34
BP	GO:0003279	cardiac septum development	28/2486	112/18670	0.0006136	0.01144	0.008963	LTBP1/ACVR1/HEYL/TBX5/SMAD7/TGFB2/PDE2A/HES1/NRP1/GJA5/MATR3/LUZP1/MDM4/NOS3/MIR17HG/SMO/FRS2/TBX2/NOTCH1/NOTCH2/HECTD1/ZFPM2/ANK2/WNT5A/TBX1/SLIT2/MYH10/PARVA	28
BP	GO:0050691	regulation of defense response to virus by host	13/2486	37/18670	0.0006316	0.01174	0.009199	TNFAIP3/TRIM6/EIF2AK4/DHX9/PARP9/ZC3H12A/PQBP1/IL23R/RNF216/DTX3L/IL1B/SIN3A/TRIM44	13
BP	GO:0007517	muscle organ development	78/2486	410/18670	0.0006463	0.01197	0.009385	SIRT2/SRI/ZNF609/YY1/MEF2D/EP300/HEYL/MYL6B/MAPK11/EVC/TBX5/CAV2/TWIST1/SMAD7/TGFB2/FXR1/AKIRIN1/TGFB1/TPM1/SERP1/CREB1/ADARB1/CYP26B1/ITGA7/FOXC1/BMP2/HLX/FOS/SGCD/SIRT1/ELN/LOX/OBSL1/CCNT2/IGF1/UBE4B/ASS1/SIX1/UTRN/HLF/MIR17HG/NR2F2/SGCE/NR1D2/EFNB2/CDON/SMO/TEAD4/POU4F1/FRS2/MEOX2/MTM1/NUPR1/TBX2/KLF5/NOTCH1/SHOX2/YAP1/JARID2/BTG2/SMTN/GPC1/ZFPM2/WNT5A/SGCB/DCN/MSX1/RYR2/CHD2/TBX1/CAV1/MTOR/DMD/CRYAB/ETV1/SOX6/HOXD9/PIN1	78
BP	GO:0042692	muscle cell differentiation	74/2486	385/18670	0.0006489	0.01199	0.009395	ARID1A/RBM4/ACVR1/EDNRB/TMOD1/YY1/BDNF/MAPK11/PRDM6/TBX5/CACNA2D2/CD9/CAV2/TMEM119/BHLHE41/TGFB1/CDK9/TPM1/PTGFRN/KDM6B/HES1/AKAP13/RBPMS2/CYP26B1/BOC/MIR21/BMP2/SGCD/NFATC4/EHD2/SIRT1/LOX/UCHL1/NPNT/OBSL1/LDB3/IGF1/SIX1/RAMP2/PDGFRA/IGFBP5/LMOD1/ALPK3/EFNB2/CDON/SMO/FRS2/PDGFRB/MORF4L2/SOX9/TBX2/KLF5/NOTCH1/SHOX2/MYH9/FLNC/ANK2/SYPL2/CSRP2/NOX4/SGCB/MSX1/ALPK2/TBX1/FER1L5/MTOR/MYH10/DMD/CSRP1/EPC1/SOX6/NFATC3/PIN1/OLFM2	74
BP	GO:0070371	ERK1 and ERK2 cascade	63/2486	317/18670	0.0006547	0.01206	0.009451	SPRY2/CHI3L1/IQGAP3/DSTYK/SLC9A3R1/TNF/FLT1/JUN/DLG1/DUSP10/CRKL/TGFB1/PHB2/SPRY1/PLA2G5/NRP1/GAS6/TNIP1/FBXW7/CX3CL1/MIR21/FLCN/FN1/FGF18/BMP2/PTGER4/CCL13/EGFR/SPRY4/NPNT/IGF1/EGF/PDGFRA/TNFRSF11A/CEACAM1/TIMP3/RAMP3/FRS2/KLF4/PDGFRB/SOX9/NOTCH1/NOTCH2/IL1B/PLA2G2A/TEK/CCL21/TREM2/GPNMB/OXTR/NOX4/FBLN1/CCL8/IL26/DUSP1/LYN/RGS14/KDR/ADCYAP1/EPHB2/PTPRC/CCL18/PIN1	63
BP	GO:0001954	positive regulation of cell-matrix adhesion	16/2486	51/18670	0.0006664	0.01224	0.009592	CSF1/PLEKHA2/NRP1/CX3CL1/COL16A1/JUP/CEACAM6/UTRN/EMP2/TEK/CCL21/SFRP1/THY1/LIMS1/PPM1F/KDR	16
BP	GO:0001776	leukocyte homeostasis	23/2486	86/18670	0.000671	0.01229	0.009629	PMAIP1/SH2B3/TNFAIP3/FADD/PPP2R3C/BCL10/TGFB1/PDE4B/P2RX7/SKIL/CXCL6/MIR17HG/PIK3CD/IL2/GAPT/PPP3CB/LYN/BAK1/TSC22D3/RC3H1/CORO1A/DOCK11/AXL	23
BP	GO:0014032	neural crest cell development	22/2486	81/18670	0.0006932	0.01266	0.009919	ACVR1/PEF1/EDNRB/SEMA3B/TWIST1/SEMA3G/PHACTR4/HES1/NRP1/NOLC1/FN1/FOXC1/EDN3/SEMA4D/SEMA6D/SEMA5B/SMO/SOX9/ALDH1A2/TBX1/SEMA3E/TCOF1	22
BP	GO:0120192	tight junction assembly	17/2486	56/18670	0.0006995	0.01273	0.009979	CLDN5/MPP5/APC/PARD3/RAB13/TNF/PARD6G/DLG1/ESAM/RAMP2/NPHP1/MYO1C/MPP7/FZD5/TJP1/PARD6A/PARD6B	17
BP	GO:0061045	negative regulation of wound healing	21/2486	76/18670	0.0007107	0.01284	0.01007	PROS1/SH2B3/PROC/CD9/CD109/DUSP10/CLASP2/SERPING1/NOS3/WFDC1/TFPI/PDGFRA/CEACAM1/PHLDB2/PLAT/C1QTNF1/CD34/FAP/CLASP1/GP1BA/ABAT	21
BP	GO:0006405	RNA export from nucleus	32/2486	135/18670	0.0007126	0.01284	0.01007	SRRM1/NXF3/EIF5A/NXT1/AKAP8L/YTHDC1/SARNP/NUP93/DHX9/RPS15/THOC2/U2AF1L4/DDX19A/NUP50/SLBP/NUP153/U2AF1/NUP210/PABPN1/RAE1/NUP188/NUP160/NUP54/NXF1/NUP214/NUP155/MCM3AP/KHDRBS1/SMG6/POLR2D/ABCE1/SETD2	32
BP	GO:0006027	glycosaminoglycan catabolic process	18/2486	61/18670	0.0007183	0.01284	0.01007	IDS/PGLYRP1/TGFB1/LYG2/AGRN/SDC2/GPC4/GPC6/BGN/LYVE1/GPC1/DCN/ACAN/OGN/CSPG4/FMOD/PRELP/HYAL1	18
BP	GO:0030521	androgen receptor signaling pathway	18/2486	61/18670	0.0007183	0.01284	0.01007	ARID1A/GRIP1/NCOA3/FHL2/EP300/HEYL/RNF6/KDM5D/DNAJA1/SAFB2/FKBP4/ZBTB7A/DAB2/SIRT1/TGFB1I1/SFRP1/TAF1/NCOA1	18
BP	GO:0045123	cellular extravasation	18/2486	61/18670	0.0007183	0.01284	0.01007	CD177/FADD/ITGA4/TNF/CRKL/IL1R1/ELANE/SELP/CX3CL1/PLVAP/PTGER4/CXCL12/PLCB1/PIK3CD/CCL21/THY1/SPN/XG	18
BP	GO:0018394	peptidyl-lysine acetylation	38/2486	169/18670	0.0007192	0.01284	0.01007	MUC1/PHF20/NCOA3/POLE3/MSL2/EP300/SNCA/TAF10/TWIST1/HAT1/YEATS2/TGFB1/LDB1/ING3/WDR5/FLCN/CREBBP/IRF4/TRRAP/GTF3C4/SIRT1/SETD5/RSF1/MORF4L2/HCFC1/MCM3AP/IL1B/EP400/CHD5/PCGF2/SET/TAF1/RPS6KA5/EPC1/PER1/SIN3A/NCOA1/ING5	38
BP	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling	30/2486	124/18670	0.0007201	0.01284	0.01007	NTF3/SLC9A3R1/PTPN13/TNF/TWIST1/FLT1/TGFB2/SELP/MIR21/IER3/IGF1R/SIRT1/EGFR/NTRK2/SEMA4D/IGF1/PDGFRA/CBL/CEACAM1/IRS2/PIK3CD/KLF4/PDGFRB/HCST/SOX9/TEK/DCN/HCLS1/LYN/KDR	30
BP	GO:0050709	negative regulation of protein secretion	33/2486	141/18670	0.0007528	0.01339	0.01049	SYTL4/TNFAIP3/ARG2/TNF/GHRL/FRMD4A/RAB11FIP1/RAB11FIP5/GAS6/FCGR2B/ADRA2A/ERP29/CX3CL1/ZC3H12A/FN1/PTGER4/JAGN1/PML/RHBDF1/BMP8A/CD34/IL1B/FKBP1B/SFRP1/IL33/PSMD9/SSC5D/REST/MIDN/NR1H4/RSAD2/SYT11/NLRP7	33
BP	GO:0030900	forebrain development	73/2486	381/18670	0.0007705	0.01367	0.01071	ANXA3/TRA2B/ARID1A/FGF13/CCDC85C/INHBA/LHX6/PLXNA3/TACC1/SCT/CRKL/RTN4RL1/CREB1/KDM6B/HES1/NRP1/TWSG1/P2RY12/BMP2/NFIB/EGFR/NTRK2/CXCL12/SATB2/PTN/AGTPBP1/PLCB1/NIN/NR2F2/CDON/SMO/AQP1/POU4F1/FRS2/SLC32A1/NOTCH1/DCLK1/MFSD2A/TSKU/ALDH1A3/KCNA1/GLI3/BTG2/ALDH1A2/LAMB1/CDK5R1/OXTR/WNT5A/FLNA/NDE1/MSX1/NR4A2/EMX2/GNG12/CHD5/SLIT2/EZH1/DLC1/DNAH5/ADCYAP1/MYH10/TACC2/SLIT1/EPHB2/NOTCH3/SUN2/SETD2/SIN3A/AXL/KIF14/SHANK3/LHX8/NCOA1	73
BP	GO:1905331	negative regulation of morphogenesis of an epithelium	8/2486	17/18670	0.0007746	0.0137	0.01074	TNF/CLASP2/MIR21/PHLDB2/SULF1/TBX2/WNT5A/CLASP1	8
BP	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	23/2486	87/18670	0.000799	0.01409	0.01104	NTF3/TNF/FLT1/TGFB2/SELP/MIR21/IGF1R/SIRT1/NTRK2/SEMA4D/IGF1/PDGFRA/CBL/IRS2/PIK3CD/PDGFRB/HCST/SOX9/TEK/DCN/HCLS1/LYN/KDR	23
BP	GO:0001945	lymph vessel development	10/2486	25/18670	0.000834	0.01463	0.01146	VEGFC/FOXC1/PDPN/VASH1/NR2F2/EFNB2/PPP3CB/PTPN14/TBX1/CCBE1	10
BP	GO:0072012	glomerulus vasculature development	10/2486	25/18670	0.000834	0.01463	0.01146	HES1/GPR4/PDGFRA/PDGFRB/CD34/NOTCH1/TEK/ANGPT2/ACTA2/NOTCH3	10
BP	GO:0046825	regulation of protein export from nucleus	13/2486	38/18670	0.0008442	0.01471	0.01153	IFI27/RBM22/AKAP8L/GAS6/RAPGEF3/PPM1A/IL1B/PTPN14/RANGAP1/ANP32B/UHMK1/BARD1/SETD2	13
BP	GO:1900024	regulation of substrate adhesion-dependent cell spreading	16/2486	52/18670	0.0008452	0.01471	0.01153	MYADM/OLFM4/LIMS2/CRKL/NRP1/ARHGEF7/PDPN/AP1AR/HAS2/NEDD9/LIMS1/FBLN1/RREB1/FLNA/ARPC2/POSTN	16
BP	GO:0006469	negative regulation of protein kinase activity	49/2486	235/18670	0.0008468	0.01471	0.01153	SPRY2/SH2B3/PDPK1/SH3BP5L/TNFAIP3/APC/PRKAR2A/DUSP10/PPP2CA/DNAJA1/SORL1/SPRY1/CDKN1C/ADARB1/IPO7/CDKN2C/IGF1R/ITPRIP/CHMP6/SIRT1/WWTR1/SMCR8/HSPB1/SFRP2/SPRY4/UCHL1/PKIB/CBL/CEACAM1/NR2F2/PLK1/PRKAG2/IL1B/IBTK/SFRP1/THY1/CDKN2B/PPM1F/IPO5/DUSP1/CD300A/CAV1/LYN/DUSP18/RGS14/PRKAR2B/EPHB2/PTPRC/LRP5	49
BP	GO:1903362	regulation of cellular protein catabolic process	51/2486	247/18670	0.0008482	0.01471	0.01153	CLU/SIRT2/MYLIP/PSMD14/GABARAPL2/ARAF/NUDT15/TNFAIP3/KEAP1/EDEM1/SMAD7/PINK1/ARIH2/HERPUD1/FBXW7/HSP90AA1/UBXN1/SMARCC1/USP7/DAB2/ECSCR/PML/CBFA2T3/RHBDF1/ZFAND2A/MSN/EGF/VCP/WAC/CSNK1A1/RCHY1/PLK3/PLK1/MTM1/NUPR1/LAPTM4B/CAMLG/IL33/TREM2/WDR91/UBE2G2/RNF139/RNF19B/CHFR/ARIH1/HSP90AB1/CAV1/RPS7/TAF1/PSME1/GIPC1	51
BP	GO:0002260	lymphocyte homeostasis	18/2486	62/18670	0.0008879	0.01535	0.01203	PMAIP1/TNFAIP3/FADD/PPP2R3C/BCL10/TGFB1/P2RX7/SKIL/MIR17HG/IL2/GAPT/PPP3CB/LYN/BAK1/TSC22D3/RC3H1/CORO1A/DOCK11	18
BP	GO:0002698	negative regulation of immune effector process	29/2486	120/18670	0.0008919	0.01538	0.01205	PARP3/HTRA1/ARG1/PGLYRP1/TNF/SMAD7/DUSP10/TGFB2/CD59/TGFB1/ITCH/GPATCH3/FCGR2B/ZC3H12A/HLX/SERPING1/TSPAN6/CEACAM1/IL13RA2/IL2/SERPINB9/IL33/PPP3CB/RNF125/CD300A/PCBP2/A2M/RC3H1/PTPRC	29
BP	GO:0031647	regulation of protein stability	57/2486	284/18670	0.0009015	0.0155	0.01215	CLU/COG3/MYLIP/DNLZ/EP300/SNCA/SMAD7/ATP1B2/NAA16/PINK1/PHB2/AHSP/CREB1/TRIM21/FBXW7/STXBP1/HSP90AA1/CREBBP/BMP2/TELO2/FBXO4/USP28/USP7/SIRT1/MDM4/ASPH/TRIM24/DERL1/SEC16A/IGF1/GPIHBP1/STK4/SMO/CCT8/PLK1/HCFC1/CAMLG/ANK2/PDCD10/FAM107A/USP33/FLNA/RNF139/MSX1/CHFR/HSP90AB1/RPS7/TAF1/WFS1/PFN1/CRYAB/GIPC1/NAA15/PIN1/NAPG/TRIM44/RASSF2	57
BP	GO:0010634	positive regulation of epithelial cell migration	38/2486	171/18670	0.0009098	0.0156	0.01223	ITGB3/ANXA3/PDPK1/SPARC/JUN/TGFB2/VEGFC/TGFB1/NRP1/CLASP2/MIR21/ZC3H12A/FGF18/CAPN7/SIRT1/NOS3/HSPB1/SMOC2/ITGA3/RHOJ/MMP9/SRPX2/BCAR1/HAS2/SOX9/TEK/ENPP2/PPM1F/RREB1/WNT5A/MAP3K3/MTOR/CLASP1/KDR/ITGA2/PFN1/HYAL1/CCBE1	38
BP	GO:0034605	cellular response to heat	32/2486	137/18670	0.0009301	0.01591	0.01247	IER5/CAMK2G/BAG4/EP300/NUP93/FKBP4/EIF2S1/HSP90AA1/CREBBP/HSF4/NUP50/ARPP21/SIRT1/STAC/NUP153/NUP210/VCP/RAE1/NUP188/NUP160/NUP54/NUP214/NUP155/CD34/HSP90AB1/MTOR/LYN/HSPA5/POLR2D/CRYAB/HSPB8/HSPA9	32
BP	GO:0014706	striated muscle tissue development	74/2486	390/18670	0.0009449	0.01612	0.01263	SIRT2/ARID1A/ACVR1/YY1/MEF2D/EP300/HEYL/MYL6B/MAPK11/TBX5/CAV2/TWIST1/SMAD7/TGFB2/AKIRIN1/TGFB1/TPM1/CREB1/KDM6B/AKAP13/CYP26B1/GJA5/SMAD1/FOXC1/BMP2/HLX/FOS/SGCD/ELN/LOX/OBSL1/CCNT2/IGF1/ADAMTS9/UBE4B/SIX1/HLF/PDGFRA/MIR17HG/NR2F2/NR1D2/ALPK3/EFNB2/CDON/SMO/POU4F1/FRS2/MEOX2/PDGFRB/MTM1/NUPR1/TBX2/KLF5/NOTCH1/SHOX2/YAP1/JARID2/BTG2/ALDH1A2/GPC1/ZFPM2/NOX4/WNT5A/SGCB/DCN/RYR2/ALPK2/TBX1/CAV1/MTOR/MYH10/SOX6/HOXD9/PIN1	74
BP	GO:0038061	NIK/NF-kappaB signaling	40/2486	183/18670	0.0009525	0.0162	0.0127	TRIP6/CHI3L1/PSMD14/PSMD12/MMP8/EP300/NFKB2/NFKBIA/TNF/NOL3/PSMD7/PSMB5/PTP4A3/TRAF4/UACA/MAP3K14/MIR21/ZC3H12A/REL/TRAF6/EGFR/CYLD/SAMD5/RELA/CARD10/TSPAN6/PPM1A/PSMB7/IL1B/PSMD1/TREM2/PSMD9/LIMS1/TLR9/PSME1/RC3H1/ZFP91/CUL1/TRIM44/RASSF2	40
BP	GO:0032963	collagen metabolic process	28/2486	115/18670	0.0009579	0.01625	0.01273	ADAMTS2/MMP8/PPARG/ARG1/PLOD2/MMP1/TNXB/TGFB1/CYGB/MIR21/SMPD3/MRC2/P2RX7/SERPINH1/ADAMTS14/MMP3/MMP9/MMP19/PDGFRB/COL5A1/CREB3L1/FAP/ITGA2/MFAP4/PRSS2/MMP25/LARP6/COL1A2	28
BP	GO:0071902	positive regulation of protein serine/threonine kinase activity	65/2486	334/18670	0.0009615	0.01627	0.01275	FAM20A/SPRY2/IQGAP3/NTF3/MAPK11/SNCA/TNF/FLT1/LTF/PPP2CA/GHRL/CRKL/TGFB1/ELANE/PRDX2/AKAP13/UBA52/CCND1/ERN1/ADRA2A/ERP29/MAP3K14/RAF1/FGF18/BMP2/TELO2/EDN3/SIRT1/TRAF6/MAP3K2/EGFR/P2RX7/SAMD5/MAP3K5/MAP3K1/CCNT2/IGF1/TPD52L1/EGF/CCNYL2/TNFRSF11A/STK4/FZD10/DBF4/CCNY/FRS2/PDGFRB/IL1B/FZD5/CDK5R1/UBC/PDCD10/NOX4/WNT5A/PAK3/TLR9/HSP90AB1/MAP3K3/MAPKAPK5/CSPG4/MADD/GHR/PDE6G/FZD4/PTPRC	65
BP	GO:0032680	regulation of tumor necrosis factor production	36/2486	160/18670	0.0009654	0.01629	0.01277	CLU/ORM1/MMP8/TNFAIP3/ARG2/FADD/ARFGEF2/TWIST1/LTF/LPL/GHRL/LILRA4/DHX9/ZFP36/GAS6/CX3CL1/ZC3H12A/NFATC4/IFIH1/HSPB1/IGF1/CD34/ACP5/TREM2/FZD5/GPNMB/WNT5A/TLR9/TBC1D23/AKAP8/SPN/FRMD8/PTPRC/NR1H4/AXL/SYT11	36
BP	GO:0002183	cytoplasmic translational initiation	12/2486	34/18670	0.0009689	0.0163	0.01278	RBM4/EIF5/EIF3L/EIF4B/YTHDF2/DENR/EIF4H/EIF3F/EIF3K/EIF3M/MTOR/EIF4A1	12
BP	GO:0051348	negative regulation of transferase activity	57/2486	285/18670	0.0009838	0.01651	0.01294	SPRY2/SH2B3/PDPK1/SH3BP5L/TNFAIP3/PPARG/PARP3/APC/PRKAR2A/SMAD7/DUSP10/PPP2CA/DNAJA1/SORL1/SPRY1/ZFP36/CDKN1C/ADARB1/IPO7/CDKN2C/IGF1R/ITPRIP/CHMP6/SIRT1/WWTR1/SMCR8/HSPB1/SFRP2/SPRY4/UCHL1/PKIB/CBL/CEACAM1/IRS2/NR2F2/PLK1/DTX3L/PRKAG2/IL1B/IBTK/SFRP1/THY1/CDKN2B/PPM1F/IPO5/DUSP1/CD300A/CAV1/RPS7/LYN/DUSP18/RGS14/MIDN/PRKAR2B/EPHB2/PTPRC/LRP5	57
BP	GO:0070555	response to interleukin-1	44/2486	207/18670	0.001007	0.01685	0.01321	CHI3L1/PSMD14/PSMD12/OTUD4/YY1/NFKBIA/MAPK11/SNCA/SQSTM1/USP10/IL1R1/PSMD7/PSMB5/LCN2/UBA52/CX3CL1/ZC3H12A/TRAF6/CCL13/RELA/PLCB1/TFPI/TNFRSF11A/PSMB7/HAS2/SOX9/IL1B/PSMD1/CCL21/SFRP1/PSMD9/UBC/RBMX/CCL8/MAP3K3/PSME1/RPS6KA5/RC3H1/ADAMTS12/CCL18/HYAL1/MTHFR/CUL1/NLRP7	44
BP	GO:2000058	regulation of ubiquitin-dependent protein catabolic process	34/2486	149/18670	0.001016	0.01692	0.01326	CLU/SIRT2/ARAF/KEAP1/SMAD7/ARIH2/HERPUD1/FBXW7/UBXN1/SMARCC1/USP7/DAB2/PML/CBFA2T3/ZFAND2A/EGF/VCP/WAC/CSNK1A1/RCHY1/PLK3/PLK1/MTM1/CAMLG/IL33/RNF139/RNF19B/CHFR/ARIH1/HSP90AB1/CAV1/RPS7/TAF1/GIPC1	34
BP	GO:0090199	regulation of release of cytochrome c from mitochondria	15/2486	48/18670	0.001017	0.01692	0.01326	CLU/PMAIP1/MFF/FXN/NOL3/PINK1/MOAP1/BCL2L1/IGF1/MMP9/BMF/TRIAP1/BAK1/PDCD5/CIDEB	15
BP	GO:0033157	regulation of intracellular protein transport	47/2486	225/18670	0.001025	0.01692	0.01326	ABLIM3/IFI27/STOM/RBM22/EDEM1/BAG4/MFF/AKAP8L/TGFB1/PINK1/SORL1/ARIH2/CACNB3/GAS6/FBXW7/NOLC1/ZC3H12A/RAPGEF3/JUP/SEC16A/NUP54/GRASP/PPM1A/SMO/PLK3/MYO1C/GLI3/IL1B/ZFAND1/FZD5/CDK5R1/PTPN14/UBE2D3/PDCD10/RANGAP1/IPO5/UBE2G2/FLNA/SH3TC2/HCLS1/SLC35D3/PDCD5/ANP32B/UHMK1/BARD1/SETD2/GDI1	47
BP	GO:0006024	glycosaminoglycan biosynthetic process	27/2486	110/18670	0.001027	0.01692	0.01326	CHST1/B4GALT2/TGFB1/AGRN/SMPD3/SDC2/GPC4/EGF/CHST3/GPC6/BGN/HS3ST2/PDGFRB/HAS2/IL1B/GPC1/HAS3/DCN/GALNT5/HAS1/ACAN/OGN/CSPG4/FMOD/PRELP/B4GALT4/HYAL1	27
BP	GO:1903320	regulation of protein modification by small protein conjugation or removal	48/2486	231/18670	0.001027	0.01692	0.01326	PEF1/TNFAIP3/OTUD4/FEM1A/SMAD7/BCL10/DNAJA1/PINK1/CDK9/MTBP/TRIM21/HERPUD1/NXN/ITCH/TNIP1/RASSF5/FBXW7/HSP90AA1/UBXN1/ZC3H12A/FBXO4/TRAF6/UBE2S/DERL1/RELA/MTA1/VCP/PRR7/RPS2/RCHY1/PLK1/DTX3L/UBE2C/CAMLG/WDR70/SKP2/FAM107A/CHFR/HSP90AB1/CAV1/RPS7/MTOR/TAF1/WFS1/HSPA5/MYCBP2/PIN1/TRIM44	48
BP	GO:0031669	cellular response to nutrient levels	49/2486	237/18670	0.001028	0.01692	0.01326	RRAGA/PMAIP1/GABARAPL2/MAP1LC3A/PPARG/DEPDC5/BCL11A/HSP90B1/EIF2AK4/JUN/LPL/SSH1/LCN2/PPM1D/KANK2/IFI16/CACNB3/GAS6/EIF2S1/STK24/P2RY12/ZC3H12A/SIRT1/SESN2/PHEX/MAX/TRIM24/P2RX7/TBL2/MAP3K5/CADPS2/PTN/CBL/P2RY2/KLF10/SESN3/CIB2/SFRP1/CDKN2B/FAM107A/USP33/MTOR/POSTN/TAF1/HSPA5/PDK4/TNC/NR1H4/NCOA1	49
BP	GO:1901653	cellular response to peptide	73/2486	385/18670	0.001039	0.01707	0.01338	GRB10/ADCY3/PDPK1/CYP11A1/ARID1B/PPARG/CASP4/ITGA4/ARG1/SLC25A33/ATP6V1E1/APC/RAB13/PRKCB/PRKAR2A/CAV2/ADCY7/LPL/GHRL/TGFB1/ADCY4/SORL1/CREB1/GRB14/FCGR2B/KLF3/ATP6V0A2/SMPD3/SMARCC1/ATP6V1G3/IGF1R/DDX11/SIRT1/MAX/SLC2A8/RARRES2/ADCY6/GLP2R/IGF1/RELA/ASS1/CEACAM1/IRS2/KLF10/AGTR1/SESN3/IDE/BCAR1/CPEB1/KLF4/MYO1C/KLF5/IL1B/CPS1/SORBS1/TREM2/RANGAP1/WDTC1/NR4A2/CAV1/CAPN10/LYN/GHR/GPR173/FBN1/RAB8A/KLF1/KL/PRKAR2B/PDK4/CDC5L/NR1H4/CPEB2	73
BP	GO:0044766	multi-organism transport	20/2486	73/18670	0.001058	0.01729	0.01355	CAV2/NUP93/THOC2/UBA52/VPS37A/NUP50/KPNA1/NUP153/NUP210/KPNA3/VPS37B/RAE1/NUP188/NUP160/NUP54/IFIT1/NUP214/NUP155/UBC/CAV1	20
BP	GO:1902579	multi-organism localization	20/2486	73/18670	0.001058	0.01729	0.01355	CAV2/NUP93/THOC2/UBA52/VPS37A/NUP50/KPNA1/NUP153/NUP210/KPNA3/VPS37B/RAE1/NUP188/NUP160/NUP54/IFIT1/NUP214/NUP155/UBC/CAV1	20
BP	GO:0071230	cellular response to amino acid stimulus	19/2486	68/18670	0.00108	0.0176	0.0138	RRAGA/COL6A1/BCL11A/TNF/COL16A1/SESN2/EGFR/BCL2L1/NTRK2/ASS1/SIX1/COL4A1/PDGFRA/SESN3/CPEB1/IPO5/MTOR/COL5A2/COL1A2	19
BP	GO:0035306	positive regulation of dephosphorylation	17/2486	58/18670	0.001086	0.01765	0.01384	PPP1R15A/PPP1R15B/SPPL3/TGFB1/PINK1/BMP2/NPNT/PDGFRB/MAGI2/CD300A/CDH5/HSP90AB1/MTOR/DLC1/ITGA2/PTPRC/PIN1	17
BP	GO:0071426	ribonucleoprotein complex export from nucleus	30/2486	127/18670	0.00109	0.01768	0.01385	SRRM1/NXF3/EIF5A/NXT1/AKAP8L/YTHDC1/SARNP/NUP93/RPS15/THOC2/U2AF1L4/DDX19A/NUP50/SLBP/NUP153/U2AF1/NUP210/PABPN1/RAE1/NUP188/NUP160/NUP54/NXF1/NUP214/NUP155/MCM3AP/SMG6/POLR2D/ABCE1/SETD2	30
BP	GO:0002821	positive regulation of adaptive immune response	26/2486	105/18670	0.001098	0.0177	0.01387	FAM49B/CD1C/FADD/EIF2AK4/TNF/IL1R1/TGFB1/FBXO38/MIR21/CD1B/NFKBIZ/HLX/BTK/SIRT1/EXOSC3/TRAF6/IL23R/P2RX7/HLA-B/IL12A/IL2/IL1B/FZD5/PTPRC/RSAD2/HLA-A	26
BP	GO:0007009	plasma membrane organization	26/2486	105/18670	0.001098	0.0177	0.01387	CLU/TLCD2/SYTL4/MPP5/SLC4A1/STX2/CAV2/TGFB2/SERP1/PACSIN1/EHD2/FNBP1L/P2RX7/MTSS1/PLSCR4/WHAMM/COL5A1/MYH9/ANK2/SYPL2/SH3TC2/FCHO1/CAV1/MYH10/PTPRC/SYT11	26
BP	GO:0060041	retina development in camera-type eye	33/2486	144/18670	0.001106	0.01779	0.01394	LRP5L/RAB11FIP4/TUB/TGFB2/HIPK1/NRP1/THRB/CLN8/MAX/MDM1/NTRK2/TGIF2/PTN/COL4A1/JMJD6/RHOJ/PDGFRA/NPHP1/ROM1/SDK1/CDON/PDGFRB/IFT140/SOX9/NDP/PRPH2/THY1/MAN2A1/MYH10/FZD4/ARHGEF15/LRP5/LPCAT1	33
BP	GO:0038179	neurotrophin signaling pathway	13/2486	39/18670	0.001114	0.01779	0.01394	SPRY2/NTF3/BDNF/SPRY1/RAF1/NTRK2/WASF1/FRS2/BCAR1/NDN/MAGI2/DOK5/CORO1A	13
BP	GO:0050730	regulation of peptidyl-tyrosine phosphorylation	52/2486	256/18670	0.001118	0.01779	0.01394	ITGB3/ACVR1/SH2B3/NTF3/SH3BP5L/GATA1/BDNF/TNF/PPP2CA/GHRL/UNC119/TGFB1/TAL1/HES1/NRP1/GAS6/CRLF1/ACE/FBXW7/ADRA2A/PARP9/CHMP6/THBS4/EGFR/NTRK2/IL23R/SFRP2/SEMA4D/IGF1/EGF/CBL/IL12A/IL2/AFAP1L2/TNFRSF14/IBTK/NEDD9/SFRP1/THY1/TREM2/ENPP2/NOX4/CD300A/CNOT7/CAV1/HCLS1/CSPG4/INPP5F/MTOR/LYN/GHR/PTPRC	52
BP	GO:0090596	sensory organ morphogenesis	52/2486	256/18670	0.001118	0.01779	0.01394	SPRY2/ARID1A/SLC9A3R1/YY1/NIPBL/TWIST1/FOXI1/PHACTR4/HIPK1/CYP26B1/THRB/WDR19/FBN2/SP3/NTRK2/SOBP/PTN/SIX1/AGTPBP1/GJB6/WNT9A/BCAR3/ROM1/SDK1/CDON/SEC24B/PRRX1/FAT1/FRS2/MFAP2/COL5A1/SOX9/TBX2/TSKU/ALDH1A3/GLI3/CTHRC1/THY1/FZD5/WNT5A/EFEMP1/MSX1/LRIG3/TBX1/SIX2/MAN2A1/BAK1/FBN1/EPHB2/COL5A2/LRP5/MYO15A	52
BP	GO:0060021	roof of mouth development	23/2486	89/18670	0.00112	0.01779	0.01394	CLDN5/INHBA/BCOR/TWIST1/DLG1/TGFB2/TIPARP/JAG2/ASPH/SATB2/PDGFRA/CSRNP1/PRRX1/MEOX2/TBX2/GLI3/WNT5A/MSX1/TBX1/PKDCC/ANP32B/EPHB2/MMP25	23
BP	GO:1903050	regulation of proteolysis involved in cellular protein catabolic process	45/2486	214/18670	0.001123	0.01779	0.01394	CLU/SIRT2/PSMD14/GABARAPL2/ARAF/NUDT15/KEAP1/EDEM1/SMAD7/PINK1/ARIH2/HERPUD1/FBXW7/UBXN1/SMARCC1/USP7/DAB2/ECSCR/PML/CBFA2T3/RHBDF1/ZFAND2A/EGF/VCP/WAC/CSNK1A1/RCHY1/PLK3/PLK1/MTM1/NUPR1/CAMLG/IL33/TREM2/UBE2G2/RNF139/RNF19B/CHFR/ARIH1/HSP90AB1/CAV1/RPS7/TAF1/PSME1/GIPC1	45
BP	GO:0043547	positive regulation of GTPase activity	76/2486	405/18670	0.001123	0.01779	0.01394	ARHGAP18/RABGAP1L/NTF3/EIF5/ARHGAP6/TBC1D10A/TAGAP/DEPDC5/ASAP2/CAV2/JUN/CRKL/SRGAP1/RAP1GAP2/AGRN/RGS7/ARHGAP10/NRP1/ASAP3/CX3CL1/FLCN/ZC3H15/RAB3GAP2/RALGAPB/ARHGAP9/RAPGEF3/NUP50/RASAL2/RGS6/ARHGEF7/CCL13/VAV1/SEMA4D/CHN2/DEPDC1/ARHGAP32/PLCB1/ARHGAP19/CHN1/FZD10/RGL3/TBC1D16/ARHGAP28/RIN3/PKP4/ARHGAP29/NEDD9/CCL21/SFRP1/THY1/ARHGEF16/CHML/LIMS1/RANGAP1/VAV3/WNT5A/CCL8/ARFGAP2/ARHGAP30/TBC1D2B/ACAP2/DLC1/ARHGAP11A/RGS14/GIT2/ADCYAP1/TBC1D9/ARHGEF12/RALGAPA2/RGS17/DOCK11/CCL18/ARHGEF15/DOCK8/PIN1/GDI1	76
BP	GO:0000302	response to reactive oxygen species	48/2486	232/18670	0.001131	0.01787	0.01401	HBB/NUDT15/MAP1LC3A/PPP1R15B/TNFAIP3/ARG1/TNF/JUN/FXN/PINK1/TPM1/LCN2/PRDX2/KDM6B/STK24/MIR21/SMPD3/FOS/BTK/PYCR1/SIRT1/SESN2/GCH1/EGFR/NOS3/MAP3K5/RELA/HP/MMP3/PDGFRA/MMP9/KCNA5/SESN3/PLK3/AQP1/KLF4/PDGFRB/FKBP1B/PDCD10/DUSP1/PCGF2/BAK1/SOD3/KPNA4/CRYAB/HYAL1/AXL/NQO1	48
BP	GO:0035567	non-canonical Wnt signaling pathway	34/2486	150/18670	0.001149	0.01811	0.01419	PSMD14/PSMD12/PLEKHA4/PSMD7/PSMB5/DAAM2/TNRC6B/GPC4/DAB2/RNF213/AP2A2/SFRP2/PLCB2/PLCB1/GPC6/FZD10/SFRP4/RSPO3/PSMB7/CTHRC1/PSMD1/SFRP1/PPP3CB/PSMD9/FZD5/WNT5A/ROR1/MAGI2/PARD6A/PDE6G/FZD4/PSME1/PFN1/PRICKLE2	34
BP	GO:0008064	regulation of actin polymerization or depolymerization	39/2486	179/18670	0.001166	0.01829	0.01434	RHOBTB1/CTTN/ARHGAP18/EPS8/CIT/TMOD1/BAG4/MYADM/ARF1/DLG1/ELN/AVIL/CXCL12/COTL1/AP1AR/PFN4/LMOD1/ARHGAP28/PLEKHH2/WHAMM/WASF1/MYO1C/CAPZA1/TMSB4Y/FCHSD2/CCL21/NCKAP1/TMSB15A/PAK3/MIR214/ARPC2/SLIT2/HCLS1/MTOR/KANK3/PFN1/CDC42EP5/CORO1A/MAGEL2	39
BP	GO:0002181	cytoplasmic translation	25/2486	100/18670	0.00117	0.01829	0.01434	RPS28/RBM4/EIF5/EIF3L/EIF4B/YTHDF2/DHX9/DENR/RPS26/RPLP1/ZC3H15/EIF4H/EIF3F/RPL29/DNAJC24/RPL39/CPEB1/RPL6/EIF3K/EIF3M/MTOR/EIF4A1/RPL9/RPL15/CPEB2	25
BP	GO:0060840	artery development	25/2486	100/18670	0.00117	0.01829	0.01434	LTBP1/HPGD/SMAD7/TGFB2/PDE2A/HES1/NRP1/GJA5/FOXC1/LUZP1/LOX/ADAMTS9/SIX1/LOXL1/EFNB2/SEC24B/PRRX1/PDGFRB/TBX2/NOTCH1/GLI3/HECTD1/TBX1/MYH10/NOTCH3	25
BP	GO:0019079	viral genome replication	29/2486	122/18670	0.001178	0.01829	0.01434	IFI27/SLPI/STOM/TRIM6/EIF2AK4/TNF/LTF/IFITM3/IFI16/GAS6/TNIP1/ADARB1/SRPK2/PPID/LARP1/ZC3H12A/ILF3/VCP/IFIT1/IFIT5/NOTCH1/IFITM2/PKN2/CCL8/CNOT7/PCBP2/STAU1/RSAD2/NR5A2	29
BP	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	29/2486	122/18670	0.001178	0.01829	0.01434	CLU/SIRT2/ARAF/KEAP1/SMAD7/ARIH2/HERPUD1/UBXN1/SMARCC1/USP7/DAB2/CBFA2T3/ZFAND2A/VCP/WAC/CSNK1A1/RCHY1/PLK3/PLK1/MTM1/CAMLG/IL33/RNF19B/CHFR/ARIH1/HSP90AB1/CAV1/TAF1/GIPC1	29
BP	GO:0072599	establishment of protein localization to endoplasmic reticulum	29/2486	122/18670	0.001178	0.01829	0.01434	SEC62/RPS27/RPS28/SEC61B/RPS15/UBA52/RPS26/RPLP1/RPL28/RPS3A/RAB3GAP2/RPL10/RPL29/TRAM1L1/RPS8/RPS4Y1/RPS2/RPL39/RPS10/SPCS1/RPL6/SPCS3/RYR2/RPL14/RPS7/HSPA5/SRP54/RPL9/RPL15	29
BP	GO:0001916	positive regulation of T cell mediated cytotoxicity	10/2486	26/18670	0.001195	0.01841	0.01443	FAM49B/CD1C/FADD/CD1B/IL23R/P2RX7/HLA-B/IL12A/PTPRC/HLA-A	10
BP	GO:0048596	embryonic camera-type eye morphogenesis	10/2486	26/18670	0.001195	0.01841	0.01443	ARID1A/TWIST1/PHACTR4/HIPK1/SP3/FRS2/TBX2/ALDH1A3/FZD5/WNT5A	10
BP	GO:0071377	cellular response to glucagon stimulus	10/2486	26/18670	0.001195	0.01841	0.01443	ADCY3/ARG1/PRKAR2A/ADCY7/ADCY4/ADCY6/GLP2R/ASS1/CPS1/PRKAR2B	10
BP	GO:0010463	mesenchymal cell proliferation	14/2486	44/18670	0.001219	0.0186	0.01458	BMP2/NFIB/PTN/SIX1/IRS2/SMO/PRRX1/SOX9/SHOX2/WNT5A/MSX1/TBX1/SIX2/LRP5	14
BP	GO:0035307	positive regulation of protein dephosphorylation	14/2486	44/18670	0.001219	0.0186	0.01458	PPP1R15A/PPP1R15B/SPPL3/TGFB1/PINK1/PDGFRB/MAGI2/CD300A/CDH5/HSP90AB1/MTOR/DLC1/PTPRC/PIN1	14
BP	GO:0038084	vascular endothelial growth factor signaling pathway	14/2486	44/18670	0.001219	0.0186	0.01458	SPRY2/FLT1/VEGFC/PTP4A3/NRP1/FOXC1/HSPB1/SMOC2/PDGFRA/PDGFRB/MYO1C/DCN/KDR/CCBE1	14
BP	GO:1902667	regulation of axon guidance	14/2486	44/18670	0.001219	0.0186	0.01458	PTPRO/SEMA3B/PLXNA3/SEMA3G/NRP1/YTHDF1/SEMA4D/CXCL12/SEMA6D/SEMA5B/WNT5A/SLIT2/SEMA3E/MYCBP2	14
BP	GO:0030833	regulation of actin filament polymerization	36/2486	162/18670	0.001222	0.0186	0.01458	RHOBTB1/CTTN/ARHGAP18/EPS8/TMOD1/BAG4/MYADM/ARF1/DLG1/ELN/AVIL/COTL1/AP1AR/PFN4/LMOD1/ARHGAP28/WHAMM/WASF1/MYO1C/CAPZA1/TMSB4Y/FCHSD2/CCL21/NCKAP1/TMSB15A/PAK3/MIR214/ARPC2/SLIT2/HCLS1/MTOR/KANK3/PFN1/CDC42EP5/CORO1A/MAGEL2	36
BP	GO:0045089	positive regulation of innate immune response	72/2486	381/18670	0.001229	0.0186	0.01458	MUC1/RBM14/PSMD14/PSMD12/COCH/CLEC4C/PDPK1/TNFAIP3/XRCC6/OTUD4/FADD/EP300/NFKBIA/TRIM6/HSP90B1/PGLYRP1/IRF1/BCL10/LTF/SFPQ/LILRA4/DHX9/PSMD7/PSMB5/IFI16/UBA52/ITCH/TNIP1/GPATCH3/MATR3/CREBBP/PARP9/RAF1/IRF4/BTK/TRAF6/PQBP1/IFIH1/CYLD/VAV1/MAP3K1/RELA/TSPAN6/IL12A/PSMB7/RAB7B/CNPY3/CD300LF/PSMD1/MUC2/PSMD9/UBC/UBE2D3/RNF125/COLEC12/WNT5A/PAK3/TLR9/NONO/CD300A/CAV1/LYN/MUC3A/PSME1/RPS6KA5/TRIL/NR1H4/RSAD2/ALPK1/SIN3A/CUL1/ZCCHC3	72
BP	GO:0021537	telencephalon development	51/2486	251/18670	0.001231	0.0186	0.01458	ANXA3/TRA2B/FGF13/CCDC85C/INHBA/LHX6/PLXNA3/TACC1/SCT/CRKL/RTN4RL1/KDM6B/HES1/NRP1/P2RY12/BMP2/NFIB/EGFR/NTRK2/CXCL12/AGTPBP1/PLCB1/NIN/CDON/SMO/AQP1/SLC32A1/MFSD2A/TSKU/ALDH1A3/KCNA1/GLI3/BTG2/LAMB1/CDK5R1/OXTR/WNT5A/FLNA/NDE1/EMX2/GNG12/SLIT2/EZH1/DNAH5/MYH10/TACC2/EPHB2/SUN2/KIF14/SHANK3/NCOA1	51
BP	GO:0060977	coronary vasculature morphogenesis	8/2486	18/18670	0.001232	0.0186	0.01458	TBX5/NRP1/SGCD/SEC24B/PDGFRB/NOTCH1/TBX1/SETD2	8
BP	GO:0034248	regulation of cellular amide metabolic process	88/2486	483/18670	0.001239	0.0186	0.01458	CLU/ENC1/ORMDL1/RBM4/PDPR/MKNK2/EIF5/TSFM/PPP1R15A/PPP1R15B/EIF5A/CNOT8/PAIP2B/RPS27L/EIF4B/EIF2AK4/SNCA/TNF/YTHDF2/NGDN/SARNP/FXR1/IREB2/DHX9/PINK1/SERP1/SORL1/TNRC6B/ZFP36/EIF2S1/RBM3/LARP1/RPLP1/NOLC1/MIR21/SMPD3/EIF1/ZC3H12A/PAIP2/ILF3/RPL10/YTHDF1/SESN2/EIF2A/HSPB1/EIF4H/IGF1/POLR2G/EEF1A1/DNAJC24/IGFBP5/CELF1/TACO1/PDP1/PLK3/CPEB1/PRR16/DIO2/BTG2/KHDRBS1/MIF4GD/YTHDF3/RNF139/MRPL13/EIF3K/RMND1/CNOT7/ORMDL2/PCIF1/MAPKAPK5/RBMS3/MTOR/METAP1/ITGA2/CDC123/SPON1/UHMK1/PDK4/POLR2D/RC3H1/PER1/TCOF1/NR1H4/EIF2B2/CNOT1/PIN1/LARP6/CPEB2	88
BP	GO:0051196	regulation of coenzyme metabolic process	24/2486	95/18670	0.001244	0.0186	0.01458	PPTC7/PDPR/ME1/SNCA/NUP93/PFKFB2/ZBTB7A/NUP50/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/RAE1/NUP188/NUP160/NUP54/PDP1/NUP214/NUP155/NUPR1/SLC2A6/PRKAG2/PDK4	24
BP	GO:0061326	renal tubule development	24/2486	95/18670	0.001244	0.0186	0.01458	IRX2/HEYL/PBX1/DLG1/TGFB1/HES1/BMP2/IRX3/WWTR1/NPNT/MTSS1/SIX1/COL4A1/HOXB7/SMO/SOX9/NOTCH1/YAP1/GLI3/HOXA11/ADAMTS16/SIX2/GZF1/LZTS2	24
BP	GO:0002687	positive regulation of leukocyte migration	30/2486	128/18670	0.001246	0.0186	0.01458	FADD/ITGA4/CSF1/TNF/VEGFC/IL1R1/AKIRIN1/TGFB1/ELANE/SELP/GAS6/P2RY12/PLVAP/EDN3/THBS4/RARRES2/CXCL12/DAPK2/PTN/IL12A/TNFRSF14/CCL21/THY1/TREM2/WNT5A/CCL8/SPN/ITGA2/XG/DOCK8	30
BP	GO:0071166	ribonucleoprotein complex localization	30/2486	128/18670	0.001246	0.0186	0.01458	SRRM1/NXF3/EIF5A/NXT1/AKAP8L/YTHDC1/SARNP/NUP93/RPS15/THOC2/U2AF1L4/DDX19A/NUP50/SLBP/NUP153/U2AF1/NUP210/PABPN1/RAE1/NUP188/NUP160/NUP54/NXF1/NUP214/NUP155/MCM3AP/SMG6/POLR2D/ABCE1/SETD2	30
BP	GO:0071706	tumor necrosis factor superfamily cytokine production	37/2486	168/18670	0.001252	0.01865	0.01462	CLU/ORM1/MMP8/TNFAIP3/ARG2/FADD/ARFGEF2/TWIST1/BCL10/LTF/LPL/GHRL/LILRA4/DHX9/ZFP36/GAS6/CX3CL1/ZC3H12A/NFATC4/IFIH1/HSPB1/IGF1/CD34/ACP5/TREM2/FZD5/GPNMB/WNT5A/TLR9/TBC1D23/AKAP8/SPN/FRMD8/PTPRC/NR1H4/AXL/SYT11	37
BP	GO:1901222	regulation of NIK/NF-kappaB signaling	28/2486	117/18670	0.001272	0.01889	0.01481	TRIP6/CHI3L1/MMP8/EP300/NFKBIA/TNF/NOL3/PTP4A3/TRAF4/UACA/MIR21/ZC3H12A/TRAF6/EGFR/CYLD/SAMD5/RELA/CARD10/TSPAN6/PPM1A/IL1B/TREM2/LIMS1/TLR9/RC3H1/ZFP91/TRIM44/RASSF2	28
BP	GO:0010721	negative regulation of cell development	66/2486	344/18670	0.001292	0.01914	0.015	SIRT2/MYLIP/FGF13/EDNRB/PTPRO/YY1/SEMA3B/RGMA/RNF6/PLXNA3/BCL11A/EIF2AK4/PBX1/TNF/DUSP10/LTF/TGFB1/RAP1GAP2/RTN4RL1/FKBP4/SORL1/DAAM2/SEMA3G/HES1/NRP1/FBXW7/CX3CL1/THRB/CRMP1/IRX3/NFATC4/SPP1/SEMA4D/ADCY6/ULK2/IGF1/SEMA6D/SEMA5B/PTN/AP1AR/MAP2/DPYSL3/LRIG2/EFNB2/TMEM98/SOX9/NOTCH1/GLI3/IL1B/PTPRG/THY1/CDK5R1/REST/FBLN1/WNT5A/SLIT2/INPP5F/GPR173/POSTN/ADCYAP1/FBN1/SEMA3E/EPHB2/NOTCH3/DDX6/GDI1	66
BP	GO:0030832	regulation of actin filament length	39/2486	180/18670	0.001302	0.01924	0.01508	RHOBTB1/CTTN/ARHGAP18/EPS8/CIT/TMOD1/BAG4/MYADM/ARF1/DLG1/ELN/AVIL/CXCL12/COTL1/AP1AR/PFN4/LMOD1/ARHGAP28/PLEKHH2/WHAMM/WASF1/MYO1C/CAPZA1/TMSB4Y/FCHSD2/CCL21/NCKAP1/TMSB15A/PAK3/MIR214/ARPC2/SLIT2/HCLS1/MTOR/KANK3/PFN1/CDC42EP5/CORO1A/MAGEL2	39
BP	GO:0042698	ovulation cycle	19/2486	69/18670	0.001308	0.01925	0.01509	INHBA/TGFB2/PAM/SIRT1/EGFR/NOS3/PTN/PDGFRA/MMP19/HAS2/TIMP4/OXTR/HAS1/SLIT2/FZD4/HSPA5/AXL/ZNF830/NCOA1	19
BP	GO:0046683	response to organophosphorus	31/2486	134/18670	0.001308	0.01925	0.01509	JUND/FOSB/SPARC/HSP90B1/JUN/CDO1/SSH1/PLA2G5/PDE2A/P2RY12/RAPGEF3/FOS/STC1/P2RX7/RELA/ASS1/P2RY2/IGFBP5/SLC26A6/AQP1/MMP19/CIB2/IL1B/TEK/CPS1/NOX4/DUSP1/TAF1/HSPA5/JUNB/PER1	31
BP	GO:0014033	neural crest cell differentiation	23/2486	90/18670	0.001318	0.01934	0.01516	ACVR1/PEF1/EDNRB/SEMA3B/TWIST1/SEMA3G/PHACTR4/HES1/NRP1/NOLC1/FN1/FOXC1/EDN3/SEMA4D/SEMA6D/SEMA5B/SMO/SOX9/SFRP1/ALDH1A2/TBX1/SEMA3E/TCOF1	23
BP	GO:0030308	negative regulation of cell growth	40/2486	186/18670	0.001321	0.01934	0.01516	FGF13/SERTAD2/PPARG/YY1/SEMA3B/INHBA/RNF6/PLXNA3/BCL11A/PPP2CA/TGFB2/TGFB1/SERTAD3/SEMA3G/NRP1/CDKN2C/FLCN/SIRT1/SESN2/SPP1/SFRP2/SEMA4D/PML/WFDC1/ULK2/ADIPOR2/SEMA6D/SEMA5B/MAP2/SFRP1/CRLF3/CDK5R1/WNT5A/MSX1/SLIT2/SEMA3E/CRYAB/RERG/HYAL1/OSGIN2	40
BP	GO:0061005	cell differentiation involved in kidney development	16/2486	54/18670	0.001327	0.01938	0.01519	PTPRO/HES1/GPR4/WWTR1/MTSS1/MMP9/SMO/GLIS2/CD34/NOTCH1/YAP1/GLI3/MAGI2/PODXL/SIX2/ACTA2	16
BP	GO:0043297	apical junction assembly	18/2486	64/18670	0.001331	0.01941	0.01521	CLDN5/MPP5/APC/PARD3/RAB13/TNF/PARD6G/DLG1/ESAM/RAMP2/NPHP1/MYO1C/MPP7/FZD5/PKN2/TJP1/PARD6A/PARD6B	18
BP	GO:0001836	release of cytochrome c from mitochondria	17/2486	59/18670	0.001339	0.01948	0.01527	CLU/PMAIP1/MFF/JUN/FXN/NOL3/PINK1/MOAP1/BCL2L1/IGF1/MMP9/BMF/IFI6/TRIAP1/BAK1/PDCD5/CIDEB	17
BP	GO:0035265	organ growth	43/2486	204/18670	0.001358	0.01967	0.01542	SPRY2/COCH/YY1/COL6A1/MAPK11/EVC/TBX5/CACNA2D2/FXN/TGFB2/SERP1/AKAP13/SMPD3/SMAD1/FOXC1/HLX/SCARA3/ECM1/STC1/IGF1/COL27A1/MIR17HG/STK4/COL14A1/THBS3/SMO/PDGFRB/SOX9/TBX2/NOTCH1/YAP1/JARID2/MATN2/ZFPM2/VIT/COL12A1/COL21A1/DDR2/VWA1/COL6A2/NLGN4X/MTOR/PIN1	43
BP	GO:0050768	negative regulation of neurogenesis	58/2486	295/18670	0.001365	0.01967	0.01542	SIRT2/MYLIP/FGF13/EDNRB/PTPRO/SEMA3B/RGMA/RNF6/PLXNA3/BCL11A/EIF2AK4/PBX1/TNF/DUSP10/TGFB1/RAP1GAP2/RTN4RL1/FKBP4/SORL1/DAAM2/SEMA3G/HES1/NRP1/CX3CL1/THRB/CRMP1/IRX3/NFATC4/SPP1/SEMA4D/ADCY6/ULK2/SEMA6D/SEMA5B/PTN/MAP2/DPYSL3/LRIG2/EFNB2/TMEM98/SOX9/NOTCH1/GLI3/IL1B/PTPRG/THY1/CDK5R1/REST/WNT5A/SLIT2/INPP5F/GPR173/ADCYAP1/SEMA3E/EPHB2/NOTCH3/DDX6/GDI1	58
BP	GO:0097529	myeloid leukocyte migration	44/2486	210/18670	0.001365	0.01967	0.01542	CXCL5/EDNRB/CD177/PTPRO/CSF1/CD9/FLT1/TGFB2/VEGFC/IL1R1/AKIRIN1/CX3CL1/P2RY12/CXCR1/PDE4B/PTGER4/EDN3/THBS4/JAGN1/CCL13/VAV1/RARRES2/ITGA9/CXCL12/DAPK2/MTUS1/CXCL6/PLCB1/TNFRSF11A/PIK3CD/HRH1/IL1B/CCL21/TREM2/CXCL1/VAV3/CCL8/DUSP1/CD300A/SLIT2/LYN/MST1/CCL18/XG	44
BP	GO:0048593	camera-type eye morphogenesis	27/2486	112/18670	0.00137	0.01967	0.01542	ARID1A/YY1/TWIST1/PHACTR4/HIPK1/THRB/SP3/PTN/WNT9A/BCAR3/ROM1/SDK1/CDON/FAT1/FRS2/SOX9/TBX2/TSKU/ALDH1A3/GLI3/THY1/FZD5/WNT5A/MAN2A1/BAK1/EPHB2/LRP5	27
BP	GO:0032640	tumor necrosis factor production	36/2486	163/18670	0.001371	0.01967	0.01542	CLU/ORM1/MMP8/TNFAIP3/ARG2/FADD/ARFGEF2/TWIST1/LTF/LPL/GHRL/LILRA4/DHX9/ZFP36/GAS6/CX3CL1/ZC3H12A/NFATC4/IFIH1/HSPB1/IGF1/CD34/ACP5/TREM2/FZD5/GPNMB/WNT5A/TLR9/TBC1D23/AKAP8/SPN/FRMD8/PTPRC/NR1H4/AXL/SYT11	36
BP	GO:1903555	regulation of tumor necrosis factor superfamily cytokine production	36/2486	163/18670	0.001371	0.01967	0.01542	CLU/ORM1/MMP8/TNFAIP3/ARG2/FADD/ARFGEF2/TWIST1/LTF/LPL/GHRL/LILRA4/DHX9/ZFP36/GAS6/CX3CL1/ZC3H12A/NFATC4/IFIH1/HSPB1/IGF1/CD34/ACP5/TREM2/FZD5/GPNMB/WNT5A/TLR9/TBC1D23/AKAP8/SPN/FRMD8/PTPRC/NR1H4/AXL/SYT11	36
BP	GO:0051100	negative regulation of binding	37/2486	169/18670	0.001402	0.02005	0.01571	SRI/SLPI/ITGA4/GATA1/NFKBIA/JUN/TDG/SORL1/IFI16/ACE/EIF2S1/FBXW7/ZNF462/CRMP1/NFATC4/DAB2/DDX11/DDIT3/CFHR2/PTPRF/MAP2/RSF1/TTBK2/ARHGAP28/IFIT1/SMO/NES/USP33/MSX1/CAV1/BTAF1/TAF1/GPSM1/HSPA5/SIN3A/NEK2/PIN1	37
BP	GO:1904468	negative regulation of tumor necrosis factor secretion	6/2486	11/18670	0.001404	0.02005	0.01571	ARG2/GHRL/CX3CL1/ZC3H12A/NR1H4/SYT11	6
BP	GO:1905475	regulation of protein localization to membrane	40/2486	187/18670	0.001468	0.02092	0.01639	PMAIP1/PDPK1/STOM/CLIP3/MFF/SQSTM1/TNF/DLG1/CRKL/TGFB1/STX8/SSH1/CACNB3/GPC4/DAB2/EGFR/BCL2L1/STAC/ITGA3/YWHAZ/PTN/STAC2/GPC6/CRIPT/GRASP/RAMP3/MYO1C/STX4/SORBS1/TREM2/GPC1/ARHGEF16/CDK5R1/LRRC15/TP53BP2/PKDCC/PDCD5/EPHB2/MRAP2/GDI1	40
BP	GO:0003401	axis elongation	11/2486	31/18670	0.00149	0.02095	0.01642	SPRY2/TGFB1/SPRY1/SFRP2/SIX1/SOX9/YAP1/SFRP1/WNT5A/MAGI2/TNC	11
BP	GO:0010458	exit from mitosis	11/2486	31/18670	0.00149	0.02095	0.01642	SIRT2/EPS8/TGFB1/PHB2/ANLN/CDKN1C/CLASP2/UBE2S/UBE2C/SIRT7/CLASP1	11
BP	GO:0044319	wound healing, spreading of cells	11/2486	31/18670	0.00149	0.02095	0.01642	CLASP2/PDPN/CEACAM1/PHLDB2/COL5A1/PDCD10/RREB1/FLNA/MTOR/CLASP1/CD151	11
BP	GO:0090505	epiboly involved in wound healing	11/2486	31/18670	0.00149	0.02095	0.01642	CLASP2/PDPN/CEACAM1/PHLDB2/COL5A1/PDCD10/RREB1/FLNA/MTOR/CLASP1/CD151	11
BP	GO:0017038	protein import	42/2486	199/18670	0.001494	0.02095	0.01642	CLU/TIMM23/DNLZ/FAM53B/MBTPS1/RBM22/TOMM20/NFKBIA/NXT1/NUP93/IPO9/TGFB1/TIMM44/PHB2/TIMM10/HEATR3/IPO7/NOLC1/HSP90AA1/ZC3H12A/NUP50/KPNA1/JUP/PML/NUP153/GRPEL1/GPIHBP1/KPNA3/NUP188/NUP54/NUP214/SMO/NUP155/RPAIN/GLI3/TNPO3/IPO5/FLNA/SIX2/HCLS1/PDCD5/KPNA4	42
BP	GO:0031032	actomyosin structure organization	42/2486	199/18670	0.001494	0.02095	0.01642	CIT/ITGB5/ARHGAP6/TMOD1/BAG4/RTKN/WASF2/CDC42BPA/TPM1/ANLN/AKAP13/NRP1/CLASP2/ASAP3/MIR21/RAPGEF3/PTGER4/ELN/OBSL1/LDB3/PDGFRA/PHLDB2/LMOD1/ARHGAP28/PDGFRB/MYH9/SFRP1/SORBS1/CSRP2/NOX4/PPM1F/MTOR/CLASP1/DLC1/TNFAIP1/MYH10/CSRP1/EPB41L1/PFN1/FHDC1/ARHGEF15/LIMCH1	42
BP	GO:0050866	negative regulation of cell activation	42/2486	199/18670	0.001494	0.02095	0.01642	SH2B3/INPP5D/TNFAIP3/ARG2/PARP3/ARG1/INHBA/CD9/PGLYRP1/IRF1/SMAD7/DLG1/TGFB1/PRDX2/CYGB/RHBDD3/FCGR2B/CX3CL1/TWSG1/MIR21/ZC3H12A/HLX/BTK/NOS3/PDGFRA/CEACAM1/IL13RA2/PDCD1LG2/C1QTNF1/IL2/TNFRSF14/GLI3/CD300LF/SFRP1/GPNMB/CD300A/LYN/SPN/RC3H1/PTPRC/AXL/ABAT	42
BP	GO:0006470	protein dephosphorylation	62/2486	321/18670	0.001503	0.02103	0.01648	PPTC7/PTP4A2/DUSP28/PPP1R15A/PPP1R15B/CAMK2G/PTPRO/PTPN13/HSP90B1/PTP4A1/TNF/PPM1J/DLG1/DUSP10/PPP2CA/SPPL3/TGFB1/SSH1/PINK1/PPM1D/PTP4A3/PHACTR4/PTPRH/PPEF2/CTDSPL/RCAN2/PPP2R5E/PTN/PTPN21/MTMR14/PTPRF/PDP1/PPM1A/PDGFRB/MTM1/PTPRG/FKBP1B/PPP3CB/PTPN14/PPM1F/RNGTT/MAGI2/DUSP1/CD300A/CDH5/HSP90AB1/MTOR/DUSP18/PPEF1/DLC1/SET/MTMR7/STYXL1/PPP1R3C/MTMR4/PTPRC/CDKN3/SSH3/PPM1N/PTPRB/IGFBP3/PIN1	62
BP	GO:0003281	ventricular septum development	20/2486	75/18670	0.001521	0.02122	0.01663	LTBP1/ACVR1/HEYL/TBX5/SMAD7/TGFB2/PDE2A/HES1/GJA5/MATR3/LUZP1/MDM4/NOS3/MIR17HG/FRS2/NOTCH1/HECTD1/ZFPM2/WNT5A/SLIT2	20
BP	GO:0009314	response to radiation	82/2486	448/18670	0.001556	0.02167	0.01698	RBM4/MSH6/C9orf116/GUCY2D/MME/POLB/JUND/XRCC6/YY1/POLE3/EP300/NIPBL/EIF2AK4/B4GALT2/JUN/UNC119/SLC1A3/TGFB1/ELANE/PPM1D/BHLHE40/CREB1/IFI16/ZRANB3/EIF2S1/CCND1/PPID/CREBBP/ABCA4/SCARA3/FBXO4/FOS/USP28/NFATC4/SIRT1/EGFR/BCL2L1/MEIS2/SFRP2/PML/RELA/CXCL12/UBE4B/SEMA5B/PTN/MTA1/TNFRSF11A/NPHP1/CBL/HRH1/IL12A/BMF/PLK3/AQP1/YAP1/DYNLRB1/POLG/NR2F6/SFRP1/ANGPT2/NOX4/DUSP1/HMGCS1/MTOR/PPEF1/TRIAP1/BAK1/RGS14/TNKS1BP1/METAP1/PDE6G/TAF1/GNGT2/MFAP4/HSPA5/JUNB/MGMT/CRYAB/PER1/PTPRC/HYAL1/RNF8	82
BP	GO:0018205	peptidyl-lysine modification	74/2486	397/18670	0.00156	0.02168	0.01699	MUC1/SIRT2/PHF20/NCOA3/RLF/POLE3/MSL2/EP300/PLOD2/BCOR/BCL11A/PRDM6/SNCA/SETD4/TAF10/TWIST1/HAT1/NUP93/YEATS2/TGFB1/CBX4/LDB1/ING3/USPL1/ARID4A/WDR5/FLCN/CREBBP/IRF4/TRRAP/GTF3C4/NUP50/SIRT1/LOX/IFIH1/SETD5/SENP6/RELA/NUP153/NUP210/JMJD6/LOXL1/RAE1/NUP188/NUP160/RSF1/NUP54/SETD1B/NUP214/NUP155/NSD1/MORF4L2/HCFC1/MCM3AP/PRDM5/JARID2/IL1B/RANGAP1/EP400/GLRX5/SENP7/CHD5/PCGF2/CTCFL/EZH1/SET/TAF1/RPS6KA5/EPC1/PER1/SETD2/SIN3A/NCOA1/ING5	74
BP	GO:0061515	myeloid cell development	19/2486	70/18670	0.001574	0.0218	0.01709	SH2B3/EPB42/PABPC4/SLC4A1/EP300/GATA1/WASF2/L3MBTL3/TRIM58/LTF/TAL1/ARID4A/FBXW7/ZBTB7A/JMJD6/FLI1/NOTCH2/FBN1/SOX6	19
BP	GO:0048640	negative regulation of developmental growth	27/2486	113/18670	0.001576	0.0218	0.01709	FGF13/YY1/SEMA3B/RNF6/MAPK11/PLXNA3/BCL11A/TBX5/DUSP10/FXN/SEMA3G/NRP1/SPP1/SFRP2/SEMA4D/ULK2/SEMA6D/SEMA5B/MIR17HG/MAP2/STK4/JARID2/SFRP1/CDK5R1/WNT5A/STC2/SEMA3E	27
BP	GO:0070972	protein localization to endoplasmic reticulum	33/2486	147/18670	0.001597	0.02204	0.01727	SEC62/RPS27/RPS28/SEC61B/PPP1R15A/RPS15/UBA52/RPS26/RPLP1/RPL28/RPS3A/RAB3GAP2/RPL10/SEC16A/RPL29/TRAM1L1/RPS8/RPS4Y1/RPS2/RPL39/RPS10/SPCS1/RPL6/KDELR3/SPCS3/ANK2/RYR2/RPL14/RPS7/HSPA5/SRP54/RPL9/RPL15	33
BP	GO:0001706	endoderm formation	15/2486	50/18670	0.001617	0.02222	0.01742	ITGB5/MMP8/ITGA4/INHBA/COL6A1/ITGA7/NANOG/FN1/COL4A2/MMP9/COL5A1/LAMB1/COL12A1/COL5A2/SETD2	15
BP	GO:0014009	glial cell proliferation	15/2486	50/18670	0.001617	0.02222	0.01742	CLU/CSF1/TNF/CREB1/HES1/CX3CL1/PTN/LGI4/NOTCH1/IL1B/IL33/TREM2/MTOR/LYN/ADCYAP1	15
BP	GO:0120193	tight junction organization	17/2486	60/18670	0.001641	0.02249	0.01763	CLDN5/MPP5/APC/PARD3/RAB13/TNF/PARD6G/DLG1/ESAM/RAMP2/NPHP1/MYO1C/MPP7/FZD5/TJP1/PARD6A/PARD6B	17
BP	GO:0071216	cellular response to biotic stimulus	48/2486	236/18670	0.001646	0.02252	0.01765	SIRT2/CXCL5/PPP1R15B/TNFAIP3/EDNRB/CTSG/NFKBIB/IRF8/ARG1/NFKBIA/TNF/BCL10/LTF/TGFB1/LCN2/PRDX2/ZFP36/FCGR2B/CX3CL1/MIR21/ZC3H12A/PDE4B/BTK/CEBPE/DDIT3/TRAF6/NOS3/RELA/PLSCR4/ASS1/PABPN1/CXCL6/TFPI/PDCD1LG2/IL12A/IL1B/TREM2/FZD5/CXCL1/WNT5A/AKAP8/LYN/WFS1/MUS81/HSPA5/NR1H4/AXL/NLRP7	48
BP	GO:0050679	positive regulation of epithelial cell proliferation	43/2486	206/18670	0.001659	0.02265	0.01775	ITGB3/IQGAP3/PDPK1/TNFAIP3/ITGA4/HTRA1/ARG1/CAV2/TWIST1/JUN/GHRL/VEGFC/LAMC1/TGFB1/NRP1/CCND1/MIR21/BMP2/EGFL7/SIRT1/THBS4/EGFR/ECM1/IGF1/CXCL12/PTN/AGTR1/SMO/APLNR/HAS2/SOX9/NOTCH1/NOTCH2/TEK/SFRP1/LAMB1/RREB1/WNT5A/TBX1/MTOR/KDR/MST1/HYAL1	43
BP	GO:0001952	regulation of cell-matrix adhesion	28/2486	119/18670	0.001671	0.02271	0.0178	ARHGAP6/CSF1/HOXA7/LDB1/PLEKHA2/NRP1/CLASP2/CX3CL1/COL16A1/JUP/CEACAM6/UTRN/PHLDB2/EMP2/TEK/CCL21/SFRP1/THY1/LIMS1/PPM1F/FAM107A/DDR2/CLASP1/DLC1/POSTN/KDR/SEMA3E/LIMCH1	28
BP	GO:0051193	regulation of cofactor metabolic process	28/2486	119/18670	0.001671	0.02271	0.0178	PPTC7/PDPR/ME1/SNCA/NUP93/PINK1/PRDX2/PFKFB2/ZBTB7A/NUP50/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/HP/MMP3/RAE1/NUP188/NUP160/NUP54/PDP1/NUP214/NUP155/NUPR1/SLC2A6/PRKAG2/PDK4	28
BP	GO:0001657	ureteric bud development	24/2486	97/18670	0.001692	0.02284	0.0179	ARG2/PBX1/SMAD7/DLG1/TGFB1/SPRY1/HES1/CRLF1/SMAD1/FOXC1/BMP2/NPNT/SIX1/HOXB7/SMO/SOX9/GLI3/HOXA11/SFRP1/ADAMTS16/SIX2/SLIT2/GZF1/LZTS2	24
BP	GO:0010771	negative regulation of cell morphogenesis involved in differentiation	24/2486	97/18670	0.001692	0.02284	0.0179	FGF13/PTPRO/SEMA3B/RNF6/PLXNA3/SEMA3G/NRP1/NFATC4/SPP1/SEMA4D/ULK2/SEMA6D/SEMA5B/AP1AR/MAP2/THY1/CDK5R1/FBLN1/WNT5A/SLIT2/POSTN/SEMA3E/EPHB2/GDI1	24
BP	GO:0032231	regulation of actin filament bundle assembly	24/2486	97/18670	0.001692	0.02284	0.0179	ARHGAP6/BAG4/WASF2/TPM1/NRP1/CLASP2/ASAP3/CX3CL1/MIR21/RAPGEF3/PTGER4/PHLDB2/ARHGAP28/SFRP1/NOX4/PPM1F/FLNA/MTOR/CLASP1/DLC1/PFN1/ARHGEF15/LIMCH1/SHANK3	24
BP	GO:0033762	response to glucagon	12/2486	36/18670	0.001714	0.02309	0.0181	ADCY3/ARG1/PRKAR2A/ADCY7/CDO1/ADCY4/CREB1/ADCY6/GLP2R/ASS1/CPS1/PRKAR2B	12
BP	GO:0048469	cell maturation	38/2486	177/18670	0.001773	0.02383	0.01868	C1QA/SIRT2/NRCAM/EPB42/EDNRB/GLDN/PPARG/CABYR/LHX6/BCL11A/L3MBTL3/YTHDF2/TRIM58/TAL1/AGRN/HES1/CDKN1C/CX3CL1/ZBTB7A/BTK/CATSPER3/PTH1R/SCLT1/SLC26A6/LGI4/RND1/BFSP1/CCL21/RXFP2/FZD5/POU2F2/NR4A2/SLC26A8/NTN4/MTOR/DEFB1/AXL/KIF14	38
BP	GO:1900037	regulation of cellular response to hypoxia	7/2486	15/18670	0.001778	0.02386	0.0187	DDAH1/NOL3/PINK1/HYOU1/MIR21/CHCHD2/CD34	7
BP	GO:0043687	post-translational protein modification	68/2486	361/18670	0.001797	0.02396	0.01878	DCAF8/LTBP1/PSMD14/PSMD12/SPSB1/PTP4A2/UBXN7/MBTPS1/KEAP1/KLHL11/PROC/CSF1/FEM1A/RAB13/HSP90B1/DCAF6/LAMC1/FSTL1/PSMD7/PSMB5/KLHL20/FBXO41/GAS6/FBXW7/FBXW8/WDR5/FLCN/FN1/SDC2/FBXO4/SPP1/CCDC8/OBSL1/RABGGTB/AGTPBP1/IGFBP4/NEURL2/IGFBP5/WSB1/MXRA8/FBXL13/FBXL8/PSMB7/SPARCL1/STT3B/CP/SPSB3/PSMD1/LAMB1/PSMD9/SKP2/CHML/FBXL14/WDTC1/VWA1/PRKCSH/STC2/ITIH2/FBN1/PSME1/WFS1/RAB8A/TNC/CHRDL1/IGFBP3/CUL1/SPSB2/FBXW2	68
BP	GO:0002792	negative regulation of peptide secretion	33/2486	148/18670	0.001798	0.02396	0.01878	SYTL4/TNFAIP3/ARG2/TNF/GHRL/FRMD4A/RAB11FIP1/RAB11FIP5/GAS6/FCGR2B/ADRA2A/ERP29/CX3CL1/ZC3H12A/FN1/PTGER4/JAGN1/PML/RHBDF1/BMP8A/CD34/IL1B/FKBP1B/SFRP1/IL33/PSMD9/SSC5D/REST/MIDN/NR1H4/RSAD2/SYT11/NLRP7	33
BP	GO:0061041	regulation of wound healing	33/2486	148/18670	0.001798	0.02396	0.01878	PROS1/SH2B3/SYTL4/TNFAIP3/PROC/CD9/CD109/DUSP10/PRDX2/SELP/CLASP2/ADRA2A/SERPING1/NOS3/WFDC1/SMOC2/PDPN/TFPI/PDGFRA/CEACAM1/PHLDB2/PLAT/C1QTNF1/CD34/MYH9/FAP/RREB1/CAV1/MTOR/LYN/CLASP1/GP1BA/ABAT	33
BP	GO:2000050	regulation of non-canonical Wnt signaling pathway	9/2486	23/18670	0.001821	0.02414	0.01892	PLEKHA4/DAAM2/DAB2/RNF213/SFRP2/SFRP4/RSPO3/SFRP1/WNT5A	9
BP	GO:0045665	negative regulation of neuron differentiation	46/2486	225/18670	0.001822	0.02414	0.01892	MYLIP/FGF13/EDNRB/PTPRO/SEMA3B/RGMA/RNF6/PLXNA3/BCL11A/EIF2AK4/PBX1/RAP1GAP2/RTN4RL1/FKBP4/SEMA3G/HES1/NRP1/THRB/CRMP1/IRX3/NFATC4/SPP1/SEMA4D/ADCY6/ULK2/SEMA6D/SEMA5B/MAP2/DPYSL3/LRIG2/EFNB2/SOX9/NOTCH1/GLI3/PTPRG/THY1/CDK5R1/REST/WNT5A/SLIT2/INPP5F/SEMA3E/EPHB2/NOTCH3/DDX6/GDI1	46
BP	GO:1990778	protein localization to cell periphery	60/2486	311/18670	0.001822	0.02414	0.01892	TTC7B/FGF13/SLC9A3R1/GRIP1/PDPK1/MPP5/BAG4/RTKN/MYADM/SLC4A1/CLIP3/RAB13/SQSTM1/TUB/TNF/DLG1/TGFB1/STX8/ANLN/PACSIN1/CACNB3/GAS6/CLASP2/STXBP1/DLG2/GRIP2/GPC4/EHD2/WDR19/DAB2/JUP/EGFR/BCL2L1/STAC/SEC16A/ITGA3/STAC2/BBS1/RAMP2/GPC6/ANK1/GRASP/RAMP3/TSPAN14/PLK1/EMP2/PDZD11/STX4/SORBS1/TREM2/ARHGEF16/ANK2/LRRC15/FLNA/SYS1/PKDCC/CAV1/RAB8A/EPHB2/MRAP2	60
BP	GO:0018105	peptidyl-serine phosphorylation	58/2486	299/18670	0.001888	0.02495	0.01955	SPRY2/MKNK2/ARAF/NTF3/PRKY/PDPK1/BAG4/TRIM6/PRKCB/SNCA/CLK1/TNF/SMAD7/TGFB1/PINK1/HIPK1/GAS6/ERN1/MAST3/HSP90AA1/RAF1/BDKRB2/RAPGEF3/EGFR/NTRK2/SFRP2/CSNK1A1/STK4/BCAR3/TTBK2/RAMP3/PLK1/NSD1/DCLK1/PKN3/CDK5R1/PDCD10/PKN2/PPM1F/WNT5A/DCLK3/HSP90AB1/CAV1/MAPKAPK5/HCLS1/TTK/INPP5F/MTOR/BAK1/SH2D3C/TNKS1BP1/TAF1/DMD/RPS6KA5/UHMK1/MAPKAP1/MARK1/RASSF2	58
BP	GO:1903311	regulation of mRNA metabolic process	62/2486	324/18670	0.001895	0.02499	0.01959	TRA2B/PSMD14/PSMD12/RBM4/CPSF7/PABPC4/MBNL1/CNOT8/WTAP/YTHDC1/YTHDF2/PAPOLA/FXR1/DHX9/PSMD7/SAFB2/HNRNPM/CDK9/PSMB5/TNRC6B/ZFP36/UBA52/RBM7/SRPK2/SF3B4/RBM3/LARP1/DCP2/ZC3H12A/ZBTB7A/EXOSC3/RBMXL1/HSPB1/POLR2G/YWHAZ/PABPN1/JMJD6/TRA2A/HNRNPK/CELF1/NUP214/ZC3H10/PSMB7/YBX1/CPEB1/PSMD1/BTG2/KHDRBS1/PSMD9/UBC/KHDRBS3/REST/RBMX/YTHDF3/CNOT7/MBNL2/MTOR/SET/PSME1/RC3H1/BARD1/CNOT1	62
BP	GO:0007159	leukocyte cell-cell adhesion	64/2486	337/18670	0.001961	0.02566	0.02011	FAM49B/PDPK1/HLA-DPB1/ARG2/CD177/FADD/ITGA4/ARG1/IRF1/TNF/SMAD7/DLG1/DUSP10/BCL10/TGFB1/IGFBP2/ELANE/PRDX2/SELP/CD276/HES1/TNIP1/FCGR2B/CD83/TWSG1/MIR21/ZC3H12A/NFKBIZ/HLX/CERCAM/TRAF6/IL23R/CYLD/VAV1/SEMA4D/IGF1/RELA/CXCL12/MSN/ASS1/STK10/CEACAM1/ITGAL/PDCD1LG2/IL12A/EFNB2/IL2/KLF4/HAS2/TNFRSF14/GLI3/IL1B/CCL21/THY1/GPNMB/PAK3/CD300A/CAV1/LYN/SPN/RC3H1/PTPRC/CORO1A/DOCK8	64
BP	GO:0072163	mesonephric epithelium development	24/2486	98/18670	0.001963	0.02566	0.02011	ARG2/PBX1/SMAD7/DLG1/TGFB1/SPRY1/HES1/CRLF1/SMAD1/FOXC1/BMP2/NPNT/SIX1/HOXB7/SMO/SOX9/GLI3/HOXA11/SFRP1/ADAMTS16/SIX2/SLIT2/GZF1/LZTS2	24
BP	GO:0072164	mesonephric tubule development	24/2486	98/18670	0.001963	0.02566	0.02011	ARG2/PBX1/SMAD7/DLG1/TGFB1/SPRY1/HES1/CRLF1/SMAD1/FOXC1/BMP2/NPNT/SIX1/HOXB7/SMO/SOX9/GLI3/HOXA11/SFRP1/ADAMTS16/SIX2/SLIT2/GZF1/LZTS2	24
BP	GO:0006606	protein import into nucleus	32/2486	143/18670	0.001966	0.02566	0.02011	FAM53B/MBTPS1/RBM22/NFKBIA/NXT1/NUP93/IPO9/TGFB1/PHB2/HEATR3/IPO7/NOLC1/ZC3H12A/NUP50/KPNA1/JUP/PML/NUP153/KPNA3/NUP188/NUP54/NUP214/SMO/NUP155/RPAIN/GLI3/TNPO3/IPO5/FLNA/SIX2/HCLS1/KPNA4	32
BP	GO:0030879	mammary gland development	32/2486	143/18670	0.001966	0.02566	0.02011	LRP5L/IQGAP3/ARG1/CSF1/ATP7B/CDO1/TGFB1/PHB2/CREB1/CCND1/PAM/PML/EGF/TNFRSF11A/IRS2/IGFBP5/SMO/SOX9/TBX2/GLI3/OXTR/RREB1/WNT5A/MSX1/CAV1/HOXA9/ITGA2/MST1/MGMT/LRP5/HOXD9/NCOA1	32
BP	GO:0031503	protein-containing complex localization	55/2486	281/18670	0.001981	0.0258	0.02022	ITGB3/SRRM1/GRIP1/NXF3/EIF5A/NXT1/AKAP8L/YTHDC1/TUB/SMAD7/DLG1/SARNP/SFPQ/NUP93/RPS15/THOC2/FKBP4/U2AF1L4/DDX19A/DLG2/GRIP2/GPC4/NUP50/SGCD/WDR19/SLBP/NUP153/U2AF1/NUP210/PABPN1/GPC6/RAE1/NUP188/NUP160/NUP54/GRASP/EFNB2/NXF1/NUP214/DNM1/NUP155/IFT140/MCM3AP/DYNLRB1/EXOC3L2/SMG6/SSNA1/IFT81/DYNLL2/ARC/RAB8A/POLR2D/STXBP6/ABCE1/SETD2	55
BP	GO:0090504	epiboly	11/2486	32/18670	0.002	0.02594	0.02033	CLASP2/PDPN/CEACAM1/PHLDB2/COL5A1/PDCD10/RREB1/FLNA/MTOR/CLASP1/CD151	11
BP	GO:1902235	regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	11/2486	32/18670	0.002	0.02594	0.02033	PMAIP1/HYOU1/HERPUD1/ERP29/RNF183/SIRT1/DDIT3/BCL2L1/SERINC3/CREB3L1/WFS1	11
BP	GO:0010977	negative regulation of neuron projection development	34/2486	155/18670	0.002067	0.02672	0.02094	MYLIP/FGF13/PTPRO/SEMA3B/RGMA/RNF6/PLXNA3/BCL11A/RAP1GAP2/RTN4RL1/FKBP4/SEMA3G/NRP1/CRMP1/NFATC4/SPP1/SEMA4D/ADCY6/ULK2/SEMA6D/SEMA5B/MAP2/DPYSL3/LRIG2/EFNB2/PTPRG/THY1/CDK5R1/WNT5A/SLIT2/INPP5F/SEMA3E/EPHB2/GDI1	34
BP	GO:0006023	aminoglycan biosynthetic process	27/2486	115/18670	0.002069	0.02672	0.02094	CHST1/B4GALT2/TGFB1/AGRN/SMPD3/SDC2/GPC4/EGF/CHST3/GPC6/BGN/HS3ST2/PDGFRB/HAS2/IL1B/GPC1/HAS3/DCN/GALNT5/HAS1/ACAN/OGN/CSPG4/FMOD/PRELP/B4GALT4/HYAL1	27
BP	GO:0045598	regulation of fat cell differentiation	30/2486	132/18670	0.002078	0.02678	0.02099	SIRT2/PPARG/TNF/DUSP10/LPL/WNT5B/TGFB1/CREB1/ZFP36/HES1/MIR21/ZC3H12A/BMP2/SIRT1/DDIT3/WWTR1/RARRES2/SFRP2/GNB3/CCDC3/STK4/TGFB1I1/KLF5/WDFY2/SFRP1/ZFPM2/WNT5A/RUNX1T1/MTOR/LRP5	30
BP	GO:0033673	negative regulation of kinase activity	51/2486	257/18670	0.002091	0.02684	0.02103	SPRY2/SH2B3/PDPK1/SH3BP5L/TNFAIP3/APC/PRKAR2A/DUSP10/PPP2CA/DNAJA1/SORL1/SPRY1/CDKN1C/ADARB1/IPO7/CDKN2C/IGF1R/ITPRIP/CHMP6/SIRT1/WWTR1/SMCR8/HSPB1/SFRP2/SPRY4/UCHL1/PKIB/CBL/CEACAM1/IRS2/NR2F2/PLK1/PRKAG2/IL1B/IBTK/SFRP1/THY1/CDKN2B/PPM1F/IPO5/DUSP1/CD300A/CAV1/LYN/DUSP18/RGS14/MIDN/PRKAR2B/EPHB2/PTPRC/LRP5	51
BP	GO:0003073	regulation of systemic arterial blood pressure	23/2486	93/18670	0.002102	0.02684	0.02103	SUCNR1/SLC2A5/DDAH1/MME/PTPRO/CTSG/NAV2/TPM1/CYP4F2/GAS6/ACE/GJA5/EDN3/HSD11B2/NOS3/NR2F2/AGTR1/EMP2/KCNK6/OXTR/ADAMTS16/POSTN/ENPEP	23
BP	GO:0072080	nephron tubule development	23/2486	93/18670	0.002102	0.02684	0.02103	IRX2/HEYL/PBX1/DLG1/TGFB1/HES1/BMP2/IRX3/WWTR1/NPNT/MTSS1/SIX1/HOXB7/SMO/SOX9/NOTCH1/YAP1/GLI3/HOXA11/ADAMTS16/SIX2/GZF1/LZTS2	23
BP	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	25/2486	104/18670	0.002108	0.02684	0.02103	CLU/MUC1/MSH6/POLB/EP300/RPS27L/TNF/MOAP1/HIPK1/IFI16/PHLDA3/USP28/NFATC4/SIRT1/BCL2L1/SFRP2/PML/SKIL/CXCL12/HNRNPK/MCL1/NUPR1/TRIAP1/BAK1/CIDEB	25
BP	GO:0014812	muscle cell migration	25/2486	104/18670	0.002108	0.02684	0.02103	ITGB3/AKIRIN1/SSH1/TPM1/SORL1/NRP1/ACE/MIR21/THBS4/IGF1/SEMA6D/SIX1/IGFBP5/PLAT/SMO/PDGFRB/HAS2/PLXNA1/NOX4/MIR214/SLIT2/POSTN/ITGA2/PARVA/IGFBP3	25
BP	GO:1901800	positive regulation of proteasomal protein catabolic process	25/2486	104/18670	0.002108	0.02684	0.02103	CLU/SIRT2/KEAP1/EDEM1/SMAD7/ARIH2/HERPUD1/FBXW7/DAB2/ECSCR/CBFA2T3/ZFAND2A/VCP/CSNK1A1/RCHY1/PLK3/PLK1/NUPR1/IL33/TREM2/RNF19B/CHFR/ARIH1/CAV1/TAF1	25
BP	GO:0048678	response to axon injury	20/2486	77/18670	0.002144	0.02724	0.02135	RGMA/ARG1/JUN/RTN4RL1/STK24/P2RY12/SPP1/MAX/PTN/PTPRF/DPYSL3/LRIG2/KLF4/GAP43/MATN2/FKBP1B/RANGAP1/INPP5F/LYN/TNC	20
BP	GO:0033002	muscle cell proliferation	48/2486	239/18670	0.002157	0.02729	0.02139	TNFAIP3/XRCC6/PPARG/MEF2D/MAPK11/TBX5/HPGD/TNF/JUN/TGFB2/AKIRIN1/TPM1/ELANE/RBPMS2/ERN1/CX3CL1/MIR21/SMPD3/SMAD1/FOXC1/ELN/TRAF6/CALCRL/EGFR/MAP3K5/IGF1/SIX1/MIR17HG/MMP9/IGFBP5/SIX5/IL12A/KLF4/PDGFRB/TBX2/NOTCH1/YAP1/JARID2/PDE1A/ZFPM2/SKP2/MIR214/OGN/MTOR/ITGA2/NOTCH3/FOXJ2/IGFBP3	48
BP	GO:0051402	neuron apoptotic process	48/2486	239/18670	0.002157	0.02729	0.02139	NTF3/CIT/PDPK1/FAIM2/POLB/FADD/BDNF/SNCA/TNF/JUN/TGFB2/PINK1/HYOU1/NRP1/CRLF1/ADARB1/SRPK2/FBXW7/STXBP1/CX3CL1/THRB/NFATC4/MAX/DDIT3/BCL2L1/NTRK2/SIX1/POU4F1/TRIM2/MCL1/NUPR1/DIABLO/BTG2/NES/CDK5R1/NLRP1/PAK3/NONO/NR4A2/HSP90AB1/SET/WFS1/HSPA5/CORO1A/AXL/NQO1/KIF14/PIN1	48
BP	GO:0048675	axon extension	28/2486	121/18670	0.002173	0.02743	0.0215	NRCAM/CTTN/SEMA3B/RNF6/PLXNA3/SEMA3G/NRP1/L1CAM/RAPH1/HSP90AA1/FN1/SEMA4D/ULK2/CXCL12/SEMA6D/SEMA5B/MAP2/DCLK1/PPP3CB/CDK5R1/WNT5A/NDN/HSP90AB1/SLIT2/SEMA3E/SLIT1/SIN3A/GDI1	28
BP	GO:0035303	regulation of dephosphorylation	43/2486	209/18670	0.002218	0.02779	0.02178	SPOCD1/SH2D4A/PPP1R15A/PPP1R15B/BAG4/PPP2R3C/HSP90B1/TNF/SPPL3/TGFB2/TGFB1/PINK1/PHACTR4/PCDH11X/DLG2/CEP192/RCAN2/BMP2/PPP2R5E/CCDC8/SEMA4D/NPNT/PTN/TMEM225/FARP1/PDGFRB/FKBP1B/SMG6/ELL/MAGI2/CD300A/CDH5/PCIF1/HSP90AB1/MTOR/DLC1/SET/ITGA2/STYXL1/MTMR4/PTPRC/IGFBP3/PIN1	43
BP	GO:1904950	negative regulation of establishment of protein localization	41/2486	197/18670	0.002219	0.02779	0.02178	SYTL4/TNFAIP3/ARG2/BAG4/TNF/DNAJA1/GHRL/FRMD4A/RAB11FIP1/RAB11FIP5/GAS6/FCGR2B/ADRA2A/ERP29/CX3CL1/ZC3H12A/FN1/PTGER4/JAGN1/PML/RHBDF1/BMP8A/CD34/IL1B/FKBP1B/SFRP1/IL33/PSMD9/SSC5D/REST/RANGAP1/PPM1F/UBE2G2/PKDCC/MIDN/BARD1/NR1H4/RSAD2/SYT11/GDI1/NLRP7	41
BP	GO:0031111	negative regulation of microtubule polymerization or depolymerization	12/2486	37/18670	0.002233	0.02779	0.02178	FGF13/NAV3/CLIP3/APC/SNCA/FKBP4/CLASP2/MAP2/TTBK2/MID1/CDH5/CLASP1	12
BP	GO:0048846	axon extension involved in axon guidance	12/2486	37/18670	0.002233	0.02779	0.02178	SEMA3B/PLXNA3/SEMA3G/NRP1/SEMA4D/CXCL12/SEMA6D/SEMA5B/WNT5A/SLIT2/SEMA3E/SLIT1	12
BP	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	12/2486	37/18670	0.002233	0.02779	0.02178	MYADM/OLFM4/LIMS2/CRKL/NRP1/ARHGEF7/HAS2/NEDD9/LIMS1/RREB1/FLNA/ARPC2	12
BP	GO:1902284	neuron projection extension involved in neuron projection guidance	12/2486	37/18670	0.002233	0.02779	0.02178	SEMA3B/PLXNA3/SEMA3G/NRP1/SEMA4D/CXCL12/SEMA6D/SEMA5B/WNT5A/SLIT2/SEMA3E/SLIT1	12
BP	GO:0010975	regulation of neuron projection development	89/2486	499/18670	0.002235	0.02779	0.02178	NRCAM/SCN1B/MYLIP/CTTN/FGF13/GRIP1/PTPRO/SEMA3B/RGMA/EP300/ARF1/BDNF/TRAK1/RNF6/PLXNA3/BCL11A/RTN4IP1/CRKL/CUX2/RAP1GAP2/RTN4RL1/RND2/FKBP4/SEMA3G/PACSIN1/NRP1/L1CAM/FBXO38/FBXW8/STK24/CX3CL1/FN1/SDC2/CRMP1/YTHDF1/NFATC4/SPP1/NTRK2/AVIL/SFRP2/SEMA4D/ADCY6/HECW2/OBSL1/SKIL/ULK2/CXCL12/ITGA3/SEMA6D/SEMA5B/ITSN2/PTN/PTPRF/CHN1/NIN/MAP2/SDK1/DPYSL3/LRIG2/EFNB2/IL2/PRRX1/KLF4/SHOX2/PLXNA1/PTPRG/FKBP1B/SFRP1/THY1/CDK5R1/WNT5A/PAK3/MAGI2/SLIT2/INPP5F/MTOR/LYN/ADCYAP1/FZD4/SEMA3E/ARC/STYXL1/HSPA5/MYCBP2/EPHB2/MARK1/SIN3A/SHANK3/GDI1	89
BP	GO:0090175	regulation of establishment of planar polarity	26/2486	110/18670	0.002241	0.02779	0.02178	PSMD14/PSMD12/PLEKHA4/PSMD7/PSMB5/GPC4/DAB2/AP2A2/SFRP2/GPC6/SEC24B/RSPO3/PSMB7/CTHRC1/PSMD1/SFRP1/PSMD9/FZD5/WNT5A/ROR1/MAGI2/PARD6A/FZD4/PSME1/PFN1/PRICKLE2	26
BP	GO:0061035	regulation of cartilage development	19/2486	72/18670	0.002248	0.02779	0.02178	MAF/TGFB1/MIR21/SMPD3/SMAD1/FGF18/BMP2/RELA/WNT9A/SOX9/SHOX2/GLI3/HOXA11/WNT5A/EFEMP1/PKDCC/SIX2/ADAMTS12/SOX6	19
BP	GO:1903556	negative regulation of tumor necrosis factor superfamily cytokine production	19/2486	72/18670	0.002248	0.02779	0.02178	ORM1/TNFAIP3/ARG2/TWIST1/LTF/GHRL/LILRA4/GAS6/CX3CL1/ZC3H12A/IGF1/CD34/ACP5/TREM2/GPNMB/AKAP8/NR1H4/AXL/SYT11	19
BP	GO:0048511	rhythmic process	57/2486	295/18670	0.00225	0.02779	0.02178	RBM4/JUND/PPARG/INHBA/EP300/NFKB2/BHLHE41/TWIST1/JUN/GHRL/SFPQ/TGFB2/ARNTL2/DHX9/BHLHE40/CREB1/FBXW7/CREBBP/NFYA/PAM/KDM2A/USP7/SIRT1/EGFR/NTRK2/NOS3/PML/PTN/MTA1/ASS1/HLF/GPR176/PDGFRA/TNFRSF11A/KLF10/HS3ST2/NR1D2/MMP19/HAS2/NR2F6/TIMP4/CDK5R1/OXTR/NCOA2/NONO/HAS1/SLIT2/MTOR/FZD4/HSPA5/MYCBP2/PER1/SIN3A/AXL/MAGEL2/ZNF830/NCOA1	57
BP	GO:0034340	response to type I interferon	24/2486	99/18670	0.00227	0.02798	0.02193	IFI27/FADD/IRF8/TRIM6/IRF1/YTHDF2/IFITM3/SAMHD1/MIR21/IRF4/JAK1/HLA-B/IFIT3/IFIT1/IFI6/IFITM2/WNT5A/YTHDF3/CNOT7/HSP90AB1/RSAD2/ABCE1/SETD2/HLA-A	24
BP	GO:0048679	regulation of axon regeneration	10/2486	28/18670	0.002296	0.02825	0.02214	RGMA/RTN4RL1/STK24/SPP1/PTN/PTPRF/LRIG2/KLF4/FKBP1B/INPP5F	10
BP	GO:2000736	regulation of stem cell differentiation	27/2486	116/18670	0.002361	0.02899	0.02272	PSMD14/PSMD12/GATA1/TRIM6/TBX5/YTHDF2/TGFB2/PSMD7/TAL1/PSMB5/LDB1/HES1/ITCH/FOXC1/PTN/PDGFRA/PSMB7/SOX9/NOTCH1/YAP1/PSMD1/PSMD9/REST/PSME1/SOX6/CDK13/HSPA9	27
BP	GO:0046677	response to antibiotic	62/2486	327/18670	0.002374	0.02908	0.02279	CLU/HBB/ADCY3/PSMD14/EPS8/MAP1LC3A/PPP1R15B/POLB/TNFAIP3/SPARC/ARG1/HPGD/ADCY7/JUN/FXN/SLC1A3/CDO1/PINK1/LCN2/TRH/KDM6B/RSRC1/CCND1/STK24/LARP1/HSP90AA1/MIR21/SMPD3/ZC3H12A/ALPL/PYCR1/DDX11/SIRT1/JAGN1/AOC3/BCL2L1/JAK1/ADCY6/MAP3K5/RELA/HP/CBL/KCNA5/IL2/AQP1/KLF4/PDGFRB/FKBP1B/PDCD10/DUSP1/PCGF2/BAK1/ADCYAP1/KPNA4/HSPA5/TNC/MGMT/CRYAB/HYAL1/AXL/NQO1/ABAT	62
BP	GO:0048588	developmental cell growth	47/2486	234/18670	0.002378	0.02908	0.02279	NRCAM/CTTN/FGF13/YY1/ITGA4/SEMA3B/BDNF/RNF6/PLXNA3/BCL11A/EIF2AK4/RND2/SEMA3G/ARIH2/AKAP13/NRP1/L1CAM/RAPH1/HSP90AA1/FN1/SPP1/SEMA4D/ULK2/IGF1/CXCL12/SEMA6D/SEMA5B/ITSN2/NIN/MAP2/WASF1/SOX9/DCLK1/PLXNA1/PPP3CB/CDK5R1/WNT5A/NDN/HSP90AB1/SLIT2/MTOR/POSTN/SEMA3E/SLIT1/SIN3A/PIN1/GDI1	47
BP	GO:0060218	hematopoietic stem cell differentiation	21/2486	83/18670	0.002387	0.02909	0.0228	PSMD14/PSMD12/GATA1/YTHDF2/PSMD7/TAL1/PSMB5/LDB1/MEOX1/ITCH/ACE/FOXC1/BATF/PSMB7/YAP1/PSMD1/SFRP1/PSMD9/CHD2/PSME1/HSPA9	21
BP	GO:0034599	cellular response to oxidative stress	58/2486	302/18670	0.002388	0.02909	0.0228	SIRT2/MAP1LC3A/TNFAIP3/ARG1/SNCA/TNF/JUN/FXN/NOL3/SFPQ/PINK1/TPM1/LCN2/PRDX2/KDM6B/EIF2S1/FBXW7/MSRB3/STK24/MIR21/SMPD3/ZC3H12A/FOS/BTK/PYCR1/SIRT1/SESN2/GCH1/EGFR/NME5/NOS3/HSPB1/PML/MAP3K5/RELA/MMP3/PDGFRA/MMP9/MELK/AQP1/KLF4/MCL1/GPX8/DIABLO/PDCD10/REST/NOX4/NONO/NR4A2/PCGF2/SOD3/MAPKAP1/STAU1/MGMT/SIN3A/AXL/NQO1/CPEB2	58
BP	GO:0045185	maintenance of protein location	25/2486	105/18670	0.002424	0.02943	0.02307	SRI/LTBP1/VPS13C/KEAP1/NFKBIA/NFKBIE/PINK1/SORL1/G3BP2/FBN2/JUP/PML/TAF3/PFN4/TMSB4Y/KDELR3/TMSB15A/RANGAP1/FLNA/DZIP1/CAV1/FBN1/HSPA5/BARD1/SUN2	25
BP	GO:0071375	cellular response to peptide hormone stimulus	61/2486	321/18670	0.002425	0.02943	0.02307	GRB10/ADCY3/PDPK1/CYP11A1/ARID1B/PPARG/ARG1/SLC25A33/ATP6V1E1/APC/RAB13/PRKCB/PRKAR2A/CAV2/ADCY7/LPL/GHRL/TGFB1/ADCY4/SORL1/CREB1/GRB14/ATP6V0A2/SMARCC1/ATP6V1G3/IGF1R/SIRT1/MAX/SLC2A8/RARRES2/ADCY6/GLP2R/RELA/ASS1/CEACAM1/IRS2/AGTR1/SESN3/IDE/BCAR1/CPEB1/MYO1C/IL1B/CPS1/SORBS1/RANGAP1/WDTC1/NR4A2/CAV1/CAPN10/LYN/GHR/GPR173/FBN1/RAB8A/KL/PRKAR2B/PDK4/CDC5L/NR1H4/CPEB2	61
BP	GO:0070167	regulation of biomineral tissue development	23/2486	94/18670	0.002439	0.02954	0.02315	ACVR1/GATA1/BCOR/TMEM119/TWIST1/LTF/TGFB1/GAS6/BMP2/FBN2/ECM1/NOS3/P2RX7/ACVR2A/PTN/SOX9/NOTCH1/ANKH/ASPN/DDR2/PKDCC/KL/MGP	23
BP	GO:0042551	neuron maturation	14/2486	47/18670	0.002462	0.02962	0.02321	C1QA/NRCAM/EDNRB/GLDN/BCL11A/AGRN/CDKN1C/CX3CL1/SCLT1/LGI4/RND1/NR4A2/NTN4/MTOR	14
BP	GO:0071398	cellular response to fatty acid	16/2486	57/18670	0.002467	0.02962	0.02321	PPARG/LPL/CREB1/ZC3H12A/NFATC4/PTGER4/ADCY6/ASS1/PTGFR/AKR1C2/CPS1/SFRP1/AKAP8/PDK4/TNC/NR1H4	16
BP	GO:0075733	intracellular transport of virus	16/2486	57/18670	0.002467	0.02962	0.02321	NUP93/UBA52/VPS37A/NUP50/KPNA1/NUP153/NUP210/KPNA3/VPS37B/RAE1/NUP188/NUP160/NUP54/NUP214/NUP155/UBC	16
BP	GO:0051961	negative regulation of nervous system development	60/2486	315/18670	0.002477	0.02962	0.02321	SIRT2/MYLIP/FGF13/EDNRB/PTPRO/SEMA3B/RGMA/RNF6/PLXNA3/BCL11A/EIF2AK4/PBX1/TNF/DUSP10/TGFB1/RAP1GAP2/RTN4RL1/FKBP4/SORL1/DAAM2/SEMA3G/HES1/NRP1/CX3CL1/THRB/CRMP1/IRX3/NFATC4/SPP1/SEMA4D/ADCY6/ULK2/SEMA6D/SEMA5B/PTN/MAP2/DPYSL3/LRIG2/EFNB2/TMEM98/SOX9/NOTCH1/GLI3/IL1B/PTPRG/THY1/CDK5R1/REST/WNT5A/SLIT2/INPP5F/GPR173/ADCYAP1/SEMA3E/SLIT1/EPHB2/NOTCH3/ARHGEF15/DDX6/GDI1	60
BP	GO:0043434	response to peptide hormone	79/2486	436/18670	0.002486	0.02962	0.02321	GRB10/ADCY3/PDPK1/CYP11A1/JUND/EDNRB/ARID1B/PPARG/SPARC/ARG1/SLC25A33/ATP6V1E1/APC/RAB13/PRKCB/PRKAR2A/CAV2/ADCY7/LPL/GHRL/CDO1/TGFB1/ADCY4/SORL1/CREB1/GRB14/ATP6V0A2/SMARCC1/ATP6V1G3/IGF1R/SIRT1/SESN2/PHEX/MAX/SLC2A8/HSD11B2/RARRES2/ADCY6/GLP2R/RELA/CXCL12/ASS1/CEACAM1/IRS2/IGFBP5/AGTR1/SESN3/IDE/BCAR1/CPEB1/KHK/MYO1C/IL1B/TEK/BTG2/CPS1/SORBS1/TIMP4/OXTR/RANGAP1/WDTC1/NR4A2/CAV1/CAPN10/STC2/MTOR/LYN/GHR/GPR173/FBN1/RAB8A/KL/PRKAR2B/PDK4/CDC5L/NR1H4/FABP3/EIF2B2/CPEB2	79
BP	GO:0030514	negative regulation of BMP signaling pathway	15/2486	52/18670	0.002487	0.02962	0.02321	HTRA1/SMAD7/SORL1/RBPMS2/TWSG1/HTRA3/SFRP2/SKIL/PPM1A/GREM2/NOTCH1/SFRP1/WNT5A/FBN1/CHRDL1	15
BP	GO:0072132	mesenchyme morphogenesis	15/2486	52/18670	0.002487	0.02962	0.02321	ACVR1/HEYL/TWIST1/TGFB2/ACTG2/FOXC1/BMP2/MDM4/NOS3/SOX9/TBX2/NOTCH1/WNT5A/MSX1/ACTA2	15
BP	GO:0030950	establishment or maintenance of actin cytoskeleton polarity	6/2486	12/18670	0.002493	0.02962	0.02321	RND2/RHOF/RND3/RND1/AQP1/MAPKAP1	6
BP	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	6/2486	12/18670	0.002493	0.02962	0.02321	TNRC6B/ZFP36/POLR2G/BTG2/CNOT7/CNOT1	6
BP	GO:0060900	embryonic camera-type eye formation	6/2486	12/18670	0.002493	0.02962	0.02321	ARID1A/TWIST1/PHACTR4/FRS2/ALDH1A3/WNT5A	6
BP	GO:0030433	ubiquitin-dependent ERAD pathway	20/2486	78/18670	0.002529	0.02993	0.02346	SEC61B/EDEM1/HSP90B1/HERPUD1/ERLIN1/DNAJB14/DNAJC10/DERL1/ERLIN2/UBE4B/VCP/STT3B/UBE2G2/RNF103/TMUB2/CAV1/AUP1/TMEM67/WFS1/HSPA5	20
BP	GO:0061333	renal tubule morphogenesis	20/2486	78/18670	0.002529	0.02993	0.02346	IRX2/PBX1/DLG1/TGFB1/HES1/BMP2/IRX3/NPNT/MTSS1/SIX1/COL4A1/HOXB7/SMO/SOX9/GLI3/HOXA11/ADAMTS16/SIX2/GZF1/LZTS2	20
BP	GO:1904019	epithelial cell apoptotic process	26/2486	111/18670	0.002563	0.03028	0.02373	PDPK1/TNFAIP3/ITGA4/TNF/ZFP36/HIPK1/GAS6/EIF2S1/JAG2/ANGPTL4/COL18A1/BCL2L1/ECSCR/MAP3K5/RAMP2/PAK4/STK4/SFRP4/NUPR1/TEK/CD248/RYR2/CAPN10/MTOR/KDR/WFS1	26
BP	GO:0018209	peptidyl-serine modification	61/2486	322/18670	0.002612	0.03074	0.02409	SPRY2/MKNK2/ARAF/NTF3/PRKY/PDPK1/BAG4/TRIM6/PRKCB/SNCA/CLK1/TNF/SMAD7/GALNT3/TGFB1/PINK1/HIPK1/GAS6/ERN1/MAST3/HSP90AA1/RAF1/BDKRB2/RAPGEF3/EGFR/NTRK2/SFRP2/CSNK1A1/BGN/STK4/BCAR3/TTBK2/RAMP3/PLK1/NSD1/DCLK1/PKN3/CDK5R1/PDCD10/PKN2/PPM1F/WNT5A/DCN/DCLK3/HSP90AB1/CAV1/MAPKAPK5/HCLS1/TTK/INPP5F/MTOR/BAK1/SH2D3C/TNKS1BP1/TAF1/DMD/RPS6KA5/UHMK1/MAPKAP1/MARK1/RASSF2	61
BP	GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	24/2486	100/18670	0.002617	0.03074	0.02409	FAM49B/CD1C/FADD/TNF/IL1R1/TGFB1/FBXO38/MIR21/CD1B/NFKBIZ/HLX/BTK/EXOSC3/TRAF6/IL23R/P2RX7/HLA-B/IL12A/IL2/IL1B/FZD5/PTPRC/RSAD2/HLA-A	24
BP	GO:0036503	ERAD pathway	24/2486	100/18670	0.002617	0.03074	0.02409	SEC61B/EDEM1/SDF2L1/HSP90B1/HERPUD1/ERLIN1/UBXN1/DNAJB14/DNAJC10/DERL1/ERLIN2/UBE4B/VCP/STT3B/UBE2G2/RNF139/RNF103/TMUB2/CAV1/AUP1/TMEM67/WFS1/HSPA5/SDF2	24
BP	GO:0010464	regulation of mesenchymal cell proliferation	11/2486	33/18670	0.002644	0.03081	0.02415	NFIB/PTN/SIX1/IRS2/SMO/PRRX1/SOX9/SHOX2/WNT5A/TBX1/LRP5	11
BP	GO:0030851	granulocyte differentiation	11/2486	33/18670	0.002644	0.03081	0.02415	C1QC/INPP5D/GATA1/L3MBTL3/TAL1/CEBPE/JAGN1/SP3/CBFA2T3/CEACAM1/HCLS1	11
BP	GO:0048011	neurotrophin TRK receptor signaling pathway	11/2486	33/18670	0.002644	0.03081	0.02415	SPRY2/NTF3/BDNF/SPRY1/RAF1/NTRK2/WASF1/FRS2/BCAR1/NDN/DOK5	11
BP	GO:0048821	erythrocyte development	11/2486	33/18670	0.002644	0.03081	0.02415	SH2B3/EPB42/SLC4A1/GATA1/L3MBTL3/TRIM58/TAL1/ARID4A/ZBTB7A/JMJD6/SOX6	11
BP	GO:0048565	digestive tract development	30/2486	134/18670	0.002648	0.03081	0.02415	EDNRB/YIPF6/NIPBL/TNF/TGFB2/SCT/CRKL/TGFB1/HES1/RBPMS2/HLX/EGFR/RARRES2/SFRP2/ASS1/PDGFRA/SMO/TBX2/KLF5/NOTCH1/SHOX2/GLI3/CPS1/SFRP1/ALDH1A2/FOXL1/OXTR/WNT5A/PKDCC/SIX2	30
BP	GO:1903531	negative regulation of secretion by cell	43/2486	211/18670	0.002676	0.03095	0.02426	SYTL4/TNFAIP3/ARG2/INHBA/SNCA/TNF/GHRL/FRMD4A/TRH/RAB11FIP1/RAB11FIP5/GAS6/FCGR2B/ADRA2A/ERP29/CX3CL1/P2RY12/ZC3H12A/FN1/PTGER4/JAGN1/PML/RHBDF1/CEACAM1/IL13RA2/BMP8A/CD34/NOTCH1/IL1B/FKBP1B/SFRP1/IL33/PSMD9/SSC5D/REST/CD300A/MIDN/STXBP6/NR1H4/RSAD2/SYT11/ABAT/NLRP7	43
BP	GO:0002761	regulation of myeloid leukocyte differentiation	27/2486	117/18670	0.002688	0.03095	0.02426	C1QC/INPP5D/FADD/INHBA/CSF1/TNF/JUN/HOXA7/LTF/TGFB1/TAL1/CREB1/FBXW7/FOS/TRAF6/IL23R/CEACAM1/KLF10/POU4F1/NOTCH2/SFRP1/TREM2/HCLS1/MTOR/LYN/FBN1/RASSF2	27
BP	GO:1900371	regulation of purine nucleotide biosynthetic process	27/2486	117/18670	0.002688	0.03095	0.02426	PDPR/SNCA/NUP93/PINK1/PFKFB2/FLCN/ZBTB7A/NUP50/NOS3/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/VCP/RAE1/NUP188/NUP160/NUP54/PDP1/NUP214/NUP155/NUPR1/SLC2A6/PRKAG2/TREM2/PDK4	27
BP	GO:0007219	Notch signaling pathway	40/2486	193/18670	0.002695	0.03095	0.02426	SPEN/PEAR1/EP300/HEYL/NFKBIA/PBX1/YTHDF2/TGFB2/TGFB1/PTP4A3/HES1/ITCH/FBXW7/JAG2/CREBBP/FOXC1/BMP2/ZBTB7A/EGFL7/GRIP2/EGFR/NOS3/EGF/MFNG/KCNA5/TSPAN14/YBX1/SOX9/TBX2/NOTCH1/DTX3L/NOTCH2/NEURL1B/TIMP4/ZNF423/PDCD10/POSTN/NOTCH3/CDH6/NR1H4	40
BP	GO:0050657	nucleic acid transport	40/2486	193/18670	0.002695	0.03095	0.02426	SRRM1/NXF3/EIF5A/TOMM20/NXT1/AKAP8L/YTHDC1/SARNP/SFPQ/NUP93/DHX9/RPS15/THOC2/ZFP36/U2AF1L4/DDX19A/NUP50/G3BP2/SLBP/NUP153/U2AF1/NUP210/PABPN1/RAE1/NUP188/NUP160/NUP54/NXF1/NUP214/NUP155/MYO1C/MRPL18/MCM3AP/KHDRBS1/SMG6/ARC/RFTN2/POLR2D/ABCE1/SETD2	40
BP	GO:0050658	RNA transport	40/2486	193/18670	0.002695	0.03095	0.02426	SRRM1/NXF3/EIF5A/TOMM20/NXT1/AKAP8L/YTHDC1/SARNP/SFPQ/NUP93/DHX9/RPS15/THOC2/ZFP36/U2AF1L4/DDX19A/NUP50/G3BP2/SLBP/NUP153/U2AF1/NUP210/PABPN1/RAE1/NUP188/NUP160/NUP54/NXF1/NUP214/NUP155/MYO1C/MRPL18/MCM3AP/KHDRBS1/SMG6/ARC/RFTN2/POLR2D/ABCE1/SETD2	40
BP	GO:0051224	negative regulation of protein transport	40/2486	193/18670	0.002695	0.03095	0.02426	SYTL4/TNFAIP3/ARG2/BAG4/TNF/GHRL/FRMD4A/RAB11FIP1/RAB11FIP5/GAS6/FCGR2B/ADRA2A/ERP29/CX3CL1/ZC3H12A/FN1/PTGER4/JAGN1/PML/RHBDF1/BMP8A/CD34/IL1B/FKBP1B/SFRP1/IL33/PSMD9/SSC5D/REST/RANGAP1/PPM1F/UBE2G2/PKDCC/MIDN/BARD1/NR1H4/RSAD2/SYT11/GDI1/NLRP7	40
BP	GO:0001837	epithelial to mesenchymal transition	31/2486	140/18670	0.002721	0.03119	0.02445	ACVR1/PEF1/HEYL/TBX5/TWIST1/SMAD7/PPP2CA/TGFB2/TGFB1/SPRY1/CLASP2/NOLC1/MIR21/FOXC1/BMP2/DAB2/WWTR1/SFRP2/PDPN/PHLDB2/TGFB1I1/HAS2/SOX9/NOTCH1/IL1B/SFRP1/WNT5A/MSX1/MTOR/CLASP1/TCOF1	31
BP	GO:0060602	branch elongation of an epithelium	8/2486	20/18670	0.002774	0.03158	0.02475	SPRY2/TGFB1/SPRY1/SIX1/SOX9/YAP1/WNT5A/TNC	8
BP	GO:0060326	cell chemotaxis	58/2486	304/18670	0.002783	0.03158	0.02475	CXCL5/EDNRB/PTPRO/CSF1/RAB13/LYST/FLT1/HSD3B7/TGFB2/CRKL/VEGFC/AKIRIN1/CH25H/NRP1/GAS6/CX3CL1/FGF18/CXCR1/PDE4B/EDN3/THBS4/CCL13/LOX/VAV1/HSPB1/RARRES2/ITGA9/SMOC2/CXCL12/DAPK2/MTUS1/PLEKHG5/PTN/CXCL6/PDGFRA/TNFRSF11A/PIK3CD/AGTR1/HRH1/IL12A/BCAR1/PDGFRB/NOTCH1/IL1B/CCL21/ARHGEF16/CXCL1/VAV3/WNT5A/CCL8/DUSP1/SLIT2/LYN/KDR/MST1/CORO1A/CCL18/PARVA	58
BP	GO:0055123	digestive system development	32/2486	146/18670	0.002783	0.03158	0.02475	EDNRB/YIPF6/NIPBL/TNF/TGFB2/SCT/CRKL/TGFB1/HES1/CDKN1C/RBPMS2/HLX/WDR19/EGFR/RARRES2/SFRP2/ASS1/PDGFRA/SMO/TBX2/KLF5/NOTCH1/SHOX2/GLI3/CPS1/SFRP1/ALDH1A2/FOXL1/OXTR/WNT5A/PKDCC/SIX2	32
BP	GO:0051492	regulation of stress fiber assembly	21/2486	84/18670	0.002792	0.03158	0.02475	ARHGAP6/BAG4/WASF2/TPM1/NRP1/CLASP2/ASAP3/MIR21/RAPGEF3/PTGER4/PHLDB2/ARHGAP28/SFRP1/NOX4/PPM1F/MTOR/CLASP1/DLC1/PFN1/ARHGEF15/LIMCH1	21
BP	GO:0016239	positive regulation of macroautophagy	18/2486	68/18670	0.002794	0.03158	0.02475	VPS13C/PINK1/LARP1/RAB3GAP2/SIRT1/SESN2/SMCR8/FYCO1/WAC/SESN3/LRSAM1/RAB12/UVRAG/DCN/KDR/GPSM1/HSPB8/SCOC	18
BP	GO:0033627	cell adhesion mediated by integrin	18/2486	68/18670	0.002794	0.03158	0.02475	MUC1/ITGB3/LPXN/ITGB5/ITGA4/TGFB2/CRKL/P2RY12/COL16A1/SFRP2/NPNT/CCL21/ITGB8/PODXL/ITGBL1/LYN/ITGA2/FBN1	18
BP	GO:0001946	lymphangiogenesis	7/2486	16/18670	0.0028	0.03158	0.02475	VEGFC/FOXC1/PDPN/VASH1/PPP3CB/PTPN14/CCBE1	7
BP	GO:0030952	establishment or maintenance of cytoskeleton polarity	7/2486	16/18670	0.0028	0.03158	0.02475	RND2/RHOF/RND3/RND1/AQP1/KIF2C/MAPKAP1	7
BP	GO:0032103	positive regulation of response to external stimulus	61/2486	323/18670	0.002812	0.03158	0.02475	SUCNR1/NTF3/MMP8/ARG1/NFKBIA/CSF1/SNCA/TNF/LPL/GHRL/VEGFC/DHX9/AKIRIN1/TGFB1/PDE2A/NRP1/GAS6/TNIP1/CX3CL1/MIR21/P2RY12/FGF18/NFKBIZ/BTK/PTGER4/EDN3/THBS4/TRAF6/EGFR/HSPB1/RARRES2/SMOC2/CXCL12/DAPK2/NEAT1/PTN/TNFRSF11A/AGTR1/OSMR/IL12A/IL2/PDGFRB/NUPR1/LRSAM1/IL1B/PLA2G2A/STX4/IL17D/FKBP1B/CCL21/IL33/TREM2/PPM1F/WNT5A/TLR9/SLIT2/KDR/ITGA2/UNC13B/CCL18/ZCCHC3	61
BP	GO:0060337	type I interferon signaling pathway	23/2486	95/18670	0.00282	0.03158	0.02475	IFI27/FADD/IRF8/TRIM6/IRF1/YTHDF2/IFITM3/SAMHD1/MIR21/IRF4/JAK1/HLA-B/IFIT3/IFIT1/IFI6/IFITM2/WNT5A/YTHDF3/CNOT7/HSP90AB1/RSAD2/ABCE1/HLA-A	23
BP	GO:0071357	cellular response to type I interferon	23/2486	95/18670	0.00282	0.03158	0.02475	IFI27/FADD/IRF8/TRIM6/IRF1/YTHDF2/IFITM3/SAMHD1/MIR21/IRF4/JAK1/HLA-B/IFIT3/IFIT1/IFI6/IFITM2/WNT5A/YTHDF3/CNOT7/HSP90AB1/RSAD2/ABCE1/HLA-A	23
BP	GO:1903076	regulation of protein localization to plasma membrane	23/2486	95/18670	0.00282	0.03158	0.02475	PDPK1/CLIP3/SQSTM1/TNF/DLG1/TGFB1/STX8/DAB2/EGFR/BCL2L1/STAC/ITGA3/STAC2/GRASP/RAMP3/STX4/SORBS1/TREM2/ARHGEF16/LRRC15/PKDCC/EPHB2/MRAP2	23
BP	GO:2000060	positive regulation of ubiquitin-dependent protein catabolic process	23/2486	95/18670	0.00282	0.03158	0.02475	CLU/SIRT2/KEAP1/SMAD7/ARIH2/HERPUD1/FBXW7/DAB2/CBFA2T3/ZFAND2A/EGF/VCP/CSNK1A1/RCHY1/PLK3/PLK1/IL33/RNF139/RNF19B/CHFR/ARIH1/CAV1/TAF1	23
BP	GO:0051028	mRNA transport	33/2486	152/18670	0.002835	0.03168	0.02483	SRRM1/NXF3/EIF5A/NXT1/AKAP8L/YTHDC1/SARNP/NUP93/DHX9/THOC2/ZFP36/U2AF1L4/DDX19A/NUP50/G3BP2/SLBP/NUP153/U2AF1/NUP210/PABPN1/RAE1/NUP188/NUP160/NUP54/NXF1/NUP214/NUP155/MYO1C/MCM3AP/SMG6/ARC/POLR2D/SETD2	33
BP	GO:0002758	innate immune response-activating signal transduction	57/2486	298/18670	0.002839	0.03168	0.02483	MUC1/PSMD14/PSMD12/CLEC4C/PDPK1/TNFAIP3/OTUD4/FADD/EP300/NFKBIA/HSP90B1/PGLYRP1/IRF1/BCL10/LTF/LILRA4/PSMD7/PSMB5/UBA52/ITCH/TNIP1/GPATCH3/CREBBP/RAF1/IRF4/BTK/TRAF6/IFIH1/CYLD/MAP3K1/RELA/TSPAN6/PSMB7/RAB7B/CNPY3/CD300LF/PSMD1/MUC2/PSMD9/UBC/UBE2D3/RNF125/COLEC12/PAK3/TLR9/CD300A/CAV1/LYN/MUC3A/PSME1/RPS6KA5/TRIL/NR1H4/RSAD2/ALPK1/CUL1/ZCCHC3	57
BP	GO:1905898	positive regulation of response to endoplasmic reticulum stress	12/2486	38/18670	0.002874	0.032	0.02508	PMAIP1/PPP1R15A/EDEM1/HERPUD1/FCGR2B/ERN1/RNF183/SIRT1/DDIT3/SERINC3/CAV1/BAK1	12
BP	GO:0003206	cardiac chamber morphogenesis	29/2486	129/18670	0.002896	0.03219	0.02523	ACVR1/HEYL/TBX5/SMAD7/TGFB2/TGFB1/TPM1/HES1/NRP1/GJA5/FOXC1/NOS3/SFRP2/CPE/UBE4B/MIR17HG/SMO/POU4F1/TBX2/NOTCH1/SHOX2/NOTCH2/TEK/ZFPM2/WNT5A/RYR2/TBX1/SLIT2/PARVA	29
BP	GO:0051817	modification of morphology or physiology of other organism involved in symbiotic interaction	26/2486	112/18670	0.002924	0.03244	0.02543	RRAGA/IFI27/STOM/CTSG/ARG1/EP300/EIF2AK4/CAV2/JUN/LTF/TGFB1/ELANE/TNIP1/CHD1/ZC3H12A/KPNA1/CAMP/BCL2L1/PABPN1/CXCL6/KPNA3/AQP1/SERPINB9/REST/CCL8/KPNA4	26
BP	GO:2000146	negative regulation of cell motility	65/2486	349/18670	0.002954	0.03268	0.02562	SLC9A3R1/PPARG/C5orf30/NAV3/SCAI/TBX5/SMAD7/HOXA7/DUSP10/TGFB1/SRGAP1/TPM1/CYGB/ADARB1/CLASP2/STK24/CX3CL1/MIR21/FLCN/PTGER4/MMRN2/JUP/SFRP2/STC1/CXCL12/ADAMTS9/CARD10/SEMA6D/VASH1/PTN/AP1AR/PLCB1/PHLDB2/NR2F2/DNAJA4/IGFBP5/DPYSL3/SULF1/MEOX2/KLF4/TIE1/NOTCH1/PTPRG/CCL21/SFRP1/IL33/THY1/ANGPT2/PDCD10/FBLN1/MIR214/DCN/HAS1/MAGI2/DUSP1/CD300A/SLIT2/CLASP1/GPR173/DLC1/SPINT2/LIMCH1/IGFBP3/PIN1/ADORA3	65
BP	GO:0051235	maintenance of location	62/2486	330/18670	0.002956	0.03268	0.02562	ITGB3/SRI/LTBP1/VPS13C/PDPK1/ITPR1/KEAP1/PPARG/NFKBIA/ATP7B/HSP90B1/SNCA/TNF/MCOLN3/NOL3/LPL/NFKBIE/TGFB1/PINK1/LCN2/SORL1/FBXW7/DIAPH1/CX3CL1/ZC3H12A/MSR1/G3BP2/FBN2/SIRT1/DDIT3/JUP/P2RX7/PML/PLCB2/PLCB1/TAF3/PFN4/APLNR/BSCL2/TMSB4Y/IL1B/IBTK/FKBP1B/CCL21/THY1/KDELR3/ANK2/UVRAG/TMSB15A/RANGAP1/FLNA/DZIP1/RYR2/CAV1/LYN/FBN1/DMD/HSPA5/BARD1/PTPRC/CORO1A/SUN2	62
BP	GO:0030193	regulation of blood coagulation	20/2486	79/18670	0.002971	0.03279	0.0257	PROS1/SH2B3/PROC/CD9/PRDX2/SELP/SERPING1/NOS3/PDPN/TFPI/PDGFRA/CEACAM1/PLAT/C1QTNF1/CD34/FAP/CAV1/LYN/GP1BA/ABAT	20
BP	GO:0007498	mesoderm development	30/2486	135/18670	0.00298	0.03284	0.02574	ITGB3/ACVR1/BMX/INHBA/PPP2CA/TAL1/LDB1/KDM6B/TWSG1/SMAD1/FOXC1/BTK/IRX3/SFRP2/ACVR2A/ITGA3/SMO/POU4F1/KLF4/TIE1/YAP1/HOXA11/ZFPM2/WNT5A/TBX1/SSBP3/SIX2/ITGA2/PALB2/SETD2	30
BP	GO:0035904	aorta development	16/2486	58/18670	0.002994	0.03293	0.02581	LTBP1/TGFB2/PDE2A/HES1/LOX/ADAMTS9/SIX1/LOXL1/EFNB2/SEC24B/PDGFRB/TBX2/NOTCH1/HECTD1/TBX1/MYH10	16
BP	GO:0032649	regulation of interferon-gamma production	24/2486	101/18670	0.003008	0.03297	0.02584	FAM49B/HLA-DPB1/FADD/IRF8/INHBA/PGLYRP1/TNF/IL1R1/CD244/CD276/GAS6/ZC3H12A/PDE4B/IL23R/PDCD1LG2/IL12A/IL2/IL1B/IL33/FZD5/WNT5A/TLR9/NR1H4/AXL	24
BP	GO:0048661	positive regulation of smooth muscle cell proliferation	24/2486	101/18670	0.003008	0.03297	0.02584	MEF2D/HPGD/TNF/JUN/ELANE/RBPMS2/ERN1/CX3CL1/MIR21/SMPD3/TRAF6/CALCRL/EGFR/MAP3K5/IGF1/MMP9/IGFBP5/PDGFRB/SKP2/MIR214/MTOR/ITGA2/NOTCH3/FOXJ2	24
BP	GO:0010717	regulation of epithelial to mesenchymal transition	22/2486	90/18670	0.003032	0.03316	0.02599	ACVR1/TBX5/TWIST1/SMAD7/PPP2CA/TGFB2/TGFB1/CLASP2/MIR21/FOXC1/BMP2/DAB2/WWTR1/SFRP2/PDPN/PHLDB2/TGFB1I1/NOTCH1/IL1B/SFRP1/MTOR/CLASP1	22
BP	GO:0030195	negative regulation of blood coagulation	15/2486	53/18670	0.003048	0.03316	0.02599	PROS1/SH2B3/PROC/CD9/SERPING1/NOS3/TFPI/PDGFRA/CEACAM1/PLAT/C1QTNF1/CD34/FAP/GP1BA/ABAT	15
BP	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	15/2486	53/18670	0.003048	0.03316	0.02599	SH2B3/NTF3/SH3BP5L/PPP2CA/CHMP6/SFRP2/SEMA4D/CBL/IBTK/SFRP1/THY1/CD300A/CAV1/INPP5F/PTPRC	15
BP	GO:0030808	regulation of nucleotide biosynthetic process	27/2486	118/18670	0.003053	0.03316	0.02599	PDPR/SNCA/NUP93/PINK1/PFKFB2/FLCN/ZBTB7A/NUP50/NOS3/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/VCP/RAE1/NUP188/NUP160/NUP54/PDP1/NUP214/NUP155/NUPR1/SLC2A6/PRKAG2/TREM2/PDK4	27
BP	GO:0045047	protein targeting to ER	27/2486	118/18670	0.003053	0.03316	0.02599	SEC62/RPS27/RPS28/SEC61B/RPS15/UBA52/RPS26/RPLP1/RPL28/RPS3A/RPL10/RPL29/TRAM1L1/RPS8/RPS4Y1/RPS2/RPL39/RPS10/SPCS1/RPL6/SPCS3/RPL14/RPS7/HSPA5/SRP54/RPL9/RPL15	27
BP	GO:0060324	face development	14/2486	48/18670	0.003057	0.03316	0.02599	CLDN5/EP300/NIPBL/TGFB1/TIPARP/RAF1/ASPH/PDGFRA/CSRNP1/ALDH1A3/ALDH1A2/WNT5A/MSX1/TBX1	14
BP	GO:0006929	substrate-dependent cell migration	10/2486	29/18670	0.003092	0.03318	0.02601	CTTN/VEGFC/FMNL1/NRP1/P2RY12/FN1/SLIT2/ITGA2/MYH10/PTPRC	10
BP	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	10/2486	29/18670	0.003092	0.03318	0.02601	EP300/CDKN1C/FLCN/CREBBP/DAB2/NPNT/TGFB1I1/CDKN2B/HSP90AB1/GIPC1	10
BP	GO:0032232	negative regulation of actin filament bundle assembly	10/2486	29/18670	0.003092	0.03318	0.02601	ARHGAP6/WASF2/CLASP2/MIR21/PHLDB2/ARHGAP28/CLASP1/DLC1/PFN1/SHANK3	10
BP	GO:0044068	modulation by symbiont of host cellular process	10/2486	29/18670	0.003092	0.03318	0.02601	EIF2AK4/TNIP1/ZC3H12A/KPNA1/BCL2L1/PABPN1/KPNA3/SERPINB9/CCL8/KPNA4	10
BP	GO:0060765	regulation of androgen receptor signaling pathway	10/2486	29/18670	0.003092	0.03318	0.02601	EP300/HEYL/RNF6/KDM5D/SAFB2/ZBTB7A/DAB2/SIRT1/SFRP1/TAF1	10
BP	GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus	10/2486	29/18670	0.003092	0.03318	0.02601	EP300/CDKN1C/FLCN/CREBBP/DAB2/NPNT/TGFB1I1/CDKN2B/HSP90AB1/GIPC1	10
BP	GO:0050714	positive regulation of protein secretion	52/2486	268/18670	0.003116	0.03338	0.02617	SRI/ORM1/SYTL4/MMP8/MBP/ARF1/MAPK11/TRIM6/TNF/TWIST1/LPL/GHRL/TGFB2/FRMD4A/VEGFC/DHX9/CD244/TGFB1/SERP1/TRH/PFKFB2/C2CD2L/PPID/PTGER4/TM7SF3/EGFR/IFIH1/P2RX7/IGF1/IRS2/IL2/TNFRSF14/CD34/IL1B/STX4/IL33/TREM2/PPP3CB/PSMD9/FZD5/NLRP1/WNT5A/IL26/PARD6A/CAPN10/POSTN/FRMD8/MYH10/UNC13B/NR1H4/ABAT/NLRP7	52
BP	GO:0090316	positive regulation of intracellular protein transport	33/2486	153/18670	0.003162	0.03382	0.02651	ABLIM3/STOM/RBM22/EDEM1/MFF/TGFB1/PINK1/SORL1/ARIH2/CACNB3/GAS6/FBXW7/ZC3H12A/RAPGEF3/JUP/SEC16A/PPM1A/SMO/PLK3/MYO1C/GLI3/IL1B/ZFAND1/FZD5/CDK5R1/UBE2D3/PDCD10/IPO5/FLNA/HCLS1/SLC35D3/PDCD5/ANP32B	33
BP	GO:0050680	negative regulation of epithelial cell proliferation	35/2486	165/18670	0.003232	0.03442	0.02698	PPARG/SPARC/CAV2/TNF/FLT1/LIMS2/CD109/DLG1/DUSP10/GHRL/TGFB2/TGFB1/PHB2/CDKN1C/FBXW7/MIR21/NFIB/SFRP2/WFDC1/MTSS1/VASH1/PTN/CEACAM1/NR2F2/SULF1/EFNB2/NUPR1/SOX9/SFRP1/CDKN2B/PDCD10/WNT5A/IL26/CAV1/INTU	35
BP	GO:0071695	anatomical structure maturation	35/2486	165/18670	0.003232	0.03442	0.02698	C1QA/SIRT2/NRCAM/EPB42/EDNRB/GLDN/BCL11A/L3MBTL3/YTHDF2/TRIM58/LTF/TGFB2/TAL1/AGRN/CDKN1C/CX3CL1/BMP2/ZBTB7A/DDIT3/NOM1/SEMA4D/IGF1/SCLT1/LGI4/RND1/THBS3/NSUN2/RXFP2/ALDH1A2/CDK5R1/WNT5A/NR4A2/CDH5/NTN4/MTOR	35
BP	GO:0000956	nuclear-transcribed mRNA catabolic process	42/2486	207/18670	0.003235	0.03442	0.02698	RPS27/RPS28/LSM4/PELO/PNRC2/CNOT8/CNOT4/PPP2CA/RPS15/LSM7/TNRC6B/ZFP36/UBA52/RPS26/RPLP1/RPL28/RPS3A/DCP2/ZC3H12A/MTPAP/RPL10/EXOSC3/RPL29/POLR2G/RPS8/RPS4Y1/RPS2/RPL39/RPS10/RPL6/BTG2/SMG6/CNOT7/RPL14/RPS7/TNKS1BP1/POLR2D/RC3H1/RPL9/RPL15/DDX6/CNOT1	42
BP	GO:0071383	cellular response to steroid hormone stimulus	49/2486	250/18670	0.003269	0.0347	0.0272	RBM14/ARID1A/GRIP1/NCOA3/FHL2/PPARG/ARG1/EP300/HEYL/RNF6/KDM5D/DNAJA1/TGFB1/SAFB2/FKBP4/PHB2/RXRB/KANK2/ZFP36/AKAP13/THRB/ZBTB7A/DAB2/SIRT1/EGFR/STC1/ASS1/TFPI/DDX54/TGFB1I1/NR2F2/NR1D2/AQP1/YAP1/NR2F6/SFRP1/SKP2/NR3C1/REST/FAM107A/NR4A2/ADCYAP1/TAF1/PER1/NCOA6/NR1H4/CNOT1/NR5A2/NCOA1	49
BP	GO:0050770	regulation of axonogenesis	38/2486	183/18670	0.003272	0.0347	0.0272	NRCAM/CTTN/FGF13/PTPRO/SEMA3B/BDNF/TRAK1/RNF6/PLXNA3/RND2/SEMA3G/NRP1/L1CAM/FN1/YTHDF1/SPP1/NTRK2/SEMA4D/SKIL/ULK2/CXCL12/SEMA6D/SEMA5B/CHN1/NIN/MAP2/SHOX2/PLXNA1/THY1/CDK5R1/WNT5A/PAK3/SLIT2/SEMA3E/MYCBP2/EPHB2/SIN3A/GDI1	38
BP	GO:0070372	regulation of ERK1 and ERK2 cascade	57/2486	300/18670	0.003303	0.03497	0.02741	SPRY2/CHI3L1/DSTYK/SLC9A3R1/TNF/FLT1/JUN/DLG1/DUSP10/CRKL/TGFB1/PHB2/SPRY1/PLA2G5/NRP1/GAS6/TNIP1/FBXW7/CX3CL1/MIR21/FLCN/FN1/FGF18/BMP2/CCL13/EGFR/SPRY4/NPNT/PDGFRA/TNFRSF11A/CEACAM1/TIMP3/RAMP3/FRS2/KLF4/PDGFRB/NOTCH1/NOTCH2/IL1B/PLA2G2A/TEK/CCL21/TREM2/GPNMB/NOX4/FBLN1/CCL8/IL26/DUSP1/LYN/RGS14/KDR/ADCYAP1/EPHB2/PTPRC/CCL18/PIN1	57
BP	GO:0051896	regulation of protein kinase B signaling	48/2486	244/18670	0.003317	0.03505	0.02747	SPRY2/CHI3L1/SH2B3/SLC9A3R1/NRG4/BAG4/TNF/DLG1/TGFB1/PINK1/GAS6/PHLDA3/CX3CL1/HSP90AA1/MIR21/FLCN/P2RY12/IGF1R/FGF18/SIRT1/DDIT3/EGFR/NTRK2/VAV1/EGF/PDGFRA/AKR1C2/IRS2/IGFBP5/PIK3CD/SESN3/C1QTNF1/RAMP3/FRS2/KLF4/PDGFRB/MTM1/TEK/CCL21/NOX4/IL26/MAGI2/HSP90AB1/HCLS1/INPP5F/MTOR/KL/AXL	48
BP	GO:0051048	negative regulation of secretion	47/2486	238/18670	0.003362	0.03547	0.0278	SYTL4/TNFAIP3/ARG2/INHBA/SNCA/TNF/GHRL/SCT/FRMD4A/CYP4F2/TRH/RAB11FIP1/RAB11FIP5/GAS6/FCGR2B/ADRA2A/ERP29/CX3CL1/P2RY12/ZC3H12A/FN1/PTGER4/JAGN1/PML/RHBDF1/EGF/CEACAM1/IL13RA2/BMP8A/CD34/NOTCH1/IL1B/FKBP1B/SFRP1/IL33/PSMD9/SSC5D/OXTR/REST/CD300A/MIDN/STXBP6/NR1H4/RSAD2/SYT11/ABAT/NLRP7	47
BP	GO:1901214	regulation of neuron death	59/2486	313/18670	0.003404	0.03585	0.0281	CLU/C1QA/NTF3/PDPK1/FAIM2/BDNF/CSF1/SNCA/TNF/JUN/TGFB2/SSH1/PINK1/SORL1/HYOU1/CREB1/NRP1/CRLF1/SRPK2/EIF2S1/FBXW7/STXBP1/FCGR2B/CX3CL1/FOS/REL/NFATC4/SIRT1/DDIT3/BCL2L1/NTRK2/MAP3K5/SIX1/CBL/EFNB2/POU4F1/TRIM2/MCL1/NUPR1/CD34/BTG2/NES/CDK5R1/GPNMB/REST/WNT5A/PAK3/NONO/NR4A2/TP53BP2/HSP90AB1/MTOR/SET/WFS1/CORO1A/AXL/NQO1/KIF14/PIN1	59
BP	GO:0010922	positive regulation of phosphatase activity	11/2486	34/18670	0.003445	0.03612	0.02831	PPP1R15A/PPP1R15B/BMP2/NPNT/PDGFRB/MAGI2/CD300A/HSP90AB1/MTOR/ITGA2/PTPRC	11
BP	GO:0001823	mesonephros development	24/2486	102/18670	0.003448	0.03612	0.02831	ARG2/PBX1/SMAD7/DLG1/TGFB1/SPRY1/HES1/CRLF1/SMAD1/FOXC1/BMP2/NPNT/SIX1/HOXB7/SMO/SOX9/GLI3/HOXA11/SFRP1/ADAMTS16/SIX2/SLIT2/GZF1/LZTS2	24
BP	GO:0035335	peptidyl-tyrosine dephosphorylation	24/2486	102/18670	0.003448	0.03612	0.02831	PTP4A2/DUSP28/PTPRO/PTPN13/PTP4A1/DUSP10/SSH1/PTP4A3/PTPRH/PTPN21/MTMR14/PTPRF/MTM1/PTPRG/PTPN14/RNGTT/DUSP1/DUSP18/MTMR7/MTMR4/PTPRC/CDKN3/SSH3/PTPRB	24
BP	GO:0044783	G1 DNA damage checkpoint	17/2486	64/18670	0.003475	0.03612	0.02831	MUC1/CRADD/CNOT8/CNOT4/EP300/RPS27L/CCND1/MDM4/PML/WAC/PLK3/BTG2/CNOT7/TRIAP1/TNKS1BP1/E2F8/CNOT1	17
BP	GO:0045670	regulation of osteoclast differentiation	17/2486	64/18670	0.003475	0.03612	0.02831	INPP5D/CSF1/TNF/LTF/CREB1/FBXW7/FOS/TRAF6/IL23R/KLF10/POU4F1/NOTCH2/SFRP1/TREM2/MTOR/FBN1/RASSF2	17
BP	GO:1900046	regulation of hemostasis	20/2486	80/18670	0.003476	0.03612	0.02831	PROS1/SH2B3/PROC/CD9/PRDX2/SELP/SERPING1/NOS3/PDPN/TFPI/PDGFRA/CEACAM1/PLAT/C1QTNF1/CD34/FAP/CAV1/LYN/GP1BA/ABAT	20
BP	GO:0008643	carbohydrate transport	32/2486	148/18670	0.003476	0.03612	0.02831	GRB10/SLC2A5/CLIP3/RTN2/RFT1/SLC35A3/PRKCB/TNF/FABP5/SMPD3/SESN2/SLC2A8/IGF1/SLC45A1/ADIPOR2/SLC25A27/IRS2/SLC26A6/AQP1/SLC2A6/PRKAG2/MFSD2A/IL1B/SORBS1/SLC2A10/SLC2A12/SLC23A1/CAPN10/SLC37A4/SLC35D3/SLC17A5/SLC37A3	32
BP	GO:0014065	phosphatidylinositol 3-kinase signaling	32/2486	148/18670	0.003476	0.03612	0.02831	SIRT2/NTF3/SLC9A3R1/PEAR1/PTPN13/TNF/TWIST1/FLT1/TGFB2/SELP/MIR21/IER3/IGF1R/SIRT1/EGFR/NTRK2/SEMA4D/IGF1/PDGFRA/CBL/CEACAM1/IRS2/PIK3CD/KLF4/PDGFRB/HCST/SOX9/TEK/DCN/HCLS1/LYN/KDR	32
BP	GO:0002053	positive regulation of mesenchymal cell proliferation	9/2486	25/18670	0.003551	0.03671	0.02878	SIX1/IRS2/SMO/PRRX1/SOX9/SHOX2/WNT5A/TBX1/LRP5	9
BP	GO:0045672	positive regulation of osteoclast differentiation	9/2486	25/18670	0.003551	0.03671	0.02878	CSF1/TNF/CREB1/FOS/TRAF6/IL23R/KLF10/POU4F1/TREM2	9
BP	GO:2000679	positive regulation of transcription regulatory region DNA binding	9/2486	25/18670	0.003551	0.03671	0.02878	EP300/TRIM6/TWIST1/TGFB1/FOXC1/TRAF6/IGF1/POU4F1/KLF4	9
BP	GO:0051236	establishment of RNA localization	40/2486	196/18670	0.003586	0.03702	0.02902	SRRM1/NXF3/EIF5A/TOMM20/NXT1/AKAP8L/YTHDC1/SARNP/SFPQ/NUP93/DHX9/RPS15/THOC2/ZFP36/U2AF1L4/DDX19A/NUP50/G3BP2/SLBP/NUP153/U2AF1/NUP210/PABPN1/RAE1/NUP188/NUP160/NUP54/NXF1/NUP214/NUP155/MYO1C/MRPL18/MCM3AP/KHDRBS1/SMG6/ARC/RFTN2/POLR2D/ABCE1/SETD2	40
BP	GO:0043401	steroid hormone mediated signaling pathway	38/2486	184/18670	0.003607	0.03708	0.02906	RBM14/ARID1A/GRIP1/NCOA3/FHL2/PPARG/EP300/HEYL/RNF6/KDM5D/DNAJA1/SAFB2/FKBP4/PHB2/RXRB/KANK2/AKAP13/THRB/ZBTB7A/DAB2/SIRT1/DDX54/TGFB1I1/NR2F2/NR1D2/YAP1/NR2F6/SFRP1/SKP2/NR3C1/NR4A2/TAF1/PER1/NCOA6/NR1H4/CNOT1/NR5A2/NCOA1	38
BP	GO:0031102	neuron projection regeneration	16/2486	59/18670	0.003609	0.03708	0.02906	RGMA/JUN/RTN4RL1/STK24/SPP1/PTN/PTPRF/LRIG2/PRRX1/KLF4/GAP43/MATN2/FKBP1B/THY1/INPP5F/TNC	16
BP	GO:0045071	negative regulation of viral genome replication	16/2486	59/18670	0.003609	0.03708	0.02906	SLPI/TRIM6/EIF2AK4/TNF/LTF/IFITM3/IFI16/TNIP1/SRPK2/ZC3H12A/ILF3/IFIT1/IFIT5/IFITM2/CCL8/RSAD2	16
BP	GO:0060071	Wnt signaling pathway, planar cell polarity pathway	25/2486	108/18670	0.003622	0.03715	0.02911	PSMD14/PSMD12/PLEKHA4/PSMD7/PSMB5/GPC4/DAB2/AP2A2/SFRP2/GPC6/RSPO3/PSMB7/CTHRC1/PSMD1/SFRP1/PSMD9/FZD5/WNT5A/ROR1/MAGI2/PARD6A/FZD4/PSME1/PFN1/PRICKLE2	25
BP	GO:0032692	negative regulation of interleukin-1 production	12/2486	39/18670	0.003656	0.03737	0.02929	TNFAIP3/GHRL/GAS6/CX3CL1/ZC3H12A/PML/IGF1/CEACAM1/ACP5/TREM2/NR1H4/NLRP7	12
BP	GO:2000826	regulation of heart morphogenesis	12/2486	39/18670	0.003656	0.03737	0.02929	ACVR1/TBX5/TWIST1/TGFB2/HES1/FOXC1/BMP2/SIX1/SMO/SOX9/TBX2/NOTCH1	12
BP	GO:0032386	regulation of intracellular transport	76/2486	423/18670	0.003702	0.03778	0.02961	ABLIM3/IFI27/RBM4/SCFD1/PDPK1/STOM/RBM22/EDEM1/BAG4/ARF1/MFF/AKAP8L/PRKCB/TRIM58/GAS1/DHX9/TGFB1/PINK1/SORL1/ARIH2/CACNB3/GAS6/FBXW7/STXBP1/NOLC1/NEFH/ZC3H12A/RAPGEF3/GPR143/EHD2/DAB2/JUP/SEC16A/C12orf4/MSN/NUP153/MAP2/NUP54/IL13RA2/GRASP/PPM1A/SEC24B/NUP214/SMO/PLK3/MYO1C/GLI3/IL1B/ZFAND1/KHDRBS1/FZD5/CDK5R1/PTPN14/UBE2D3/PDCD10/RANGAP1/IPO5/UBE2G2/FLNA/SH3TC2/RNF139/CD300A/CAPN10/HCLS1/INPP5F/LYN/SLC35D3/PDCD5/ANP32B/UHMK1/UNC13B/CRYAB/BARD1/GIPC1/SETD2/GDI1	76
BP	GO:1900047	negative regulation of hemostasis	15/2486	54/18670	0.003711	0.03781	0.02963	PROS1/SH2B3/PROC/CD9/SERPING1/NOS3/TFPI/PDGFRA/CEACAM1/PLAT/C1QTNF1/CD34/FAP/GP1BA/ABAT	15
BP	GO:0051591	response to cAMP	23/2486	97/18670	0.003736	0.038	0.02978	JUND/FOSB/SPARC/JUN/CDO1/PLA2G5/PDE2A/RAPGEF3/FOS/STC1/RELA/ASS1/IGFBP5/SLC26A6/AQP1/MMP19/TEK/CPS1/NOX4/DUSP1/HSPA5/JUNB/PER1	23
BP	GO:0035850	epithelial cell differentiation involved in kidney development	13/2486	44/18670	0.003754	0.03811	0.02987	PTPRO/GPR4/WWTR1/MTSS1/MMP9/SMO/CD34/NOTCH1/YAP1/MAGI2/PODXL/SIX2/ACTA2	13
BP	GO:0001913	T cell mediated cytotoxicity	14/2486	49/18670	0.003765	0.03811	0.02987	FAM49B/CD1C/FADD/FCGR2B/CD1B/IL23R/P2RX7/HLA-B/CEACAM1/IL12A/EMP2/PPP3CB/PTPRC/HLA-A	14
BP	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	14/2486	49/18670	0.003765	0.03811	0.02987	PMAIP1/FADD/INHBA/BCL10/DEDD2/PDIA3/CYLD/PML/SKIL/STK4/TIMP3/SFRP1/CAV1/PTPRC	14
BP	GO:0043406	positive regulation of MAP kinase activity	50/2486	258/18670	0.003785	0.03824	0.02998	IQGAP3/NTF3/MAPK11/TNF/FLT1/GHRL/CRKL/TGFB1/ELANE/PRDX2/AKAP13/UBA52/ERN1/ADRA2A/ERP29/MAP3K14/RAF1/FGF18/BMP2/EDN3/TRAF6/MAP3K2/EGFR/P2RX7/SAMD5/MAP3K5/MAP3K1/IGF1/TPD52L1/EGF/TNFRSF11A/FZD10/FRS2/PDGFRB/IL1B/FZD5/UBC/PDCD10/NOX4/WNT5A/PAK3/TLR9/MAP3K3/MAPKAPK5/CSPG4/MADD/GHR/PDE6G/FZD4/PTPRC	50
BP	GO:0032388	positive regulation of intracellular transport	43/2486	215/18670	0.00384	0.03875	0.03037	ABLIM3/STOM/RBM22/EDEM1/ARF1/MFF/DHX9/TGFB1/PINK1/SORL1/ARIH2/CACNB3/GAS6/FBXW7/STXBP1/ZC3H12A/RAPGEF3/EHD2/DAB2/JUP/SEC16A/MSN/MAP2/PPM1A/SMO/PLK3/MYO1C/GLI3/IL1B/ZFAND1/KHDRBS1/FZD5/CDK5R1/UBE2D3/PDCD10/IPO5/FLNA/CAPN10/HCLS1/SLC35D3/PDCD5/ANP32B/UNC13B	43
BP	GO:0003014	renal system process	27/2486	120/18670	0.003908	0.03931	0.03081	HBB/ADCY3/SUCNR1/SLC9A3R1/EDNRB/PTPRO/SLC4A1/PRKAR2A/ADCY7/CYP4F2/ADCY4/GAS6/GJA5/HSD11B2/STC1/ADCY6/ITGA3/AGTR1/SULF1/KCNMA1/AQP1/EMP2/HAS2/CD34/MCAM/WFS1/PRKAR2B	27
BP	GO:1903052	positive regulation of proteolysis involved in cellular protein catabolic process	27/2486	120/18670	0.003908	0.03931	0.03081	CLU/SIRT2/KEAP1/EDEM1/SMAD7/ARIH2/HERPUD1/FBXW7/DAB2/ECSCR/CBFA2T3/ZFAND2A/EGF/VCP/CSNK1A1/RCHY1/PLK3/PLK1/NUPR1/IL33/TREM2/RNF139/RNF19B/CHFR/ARIH1/CAV1/TAF1	27
BP	GO:0032720	negative regulation of tumor necrosis factor production	18/2486	70/18670	0.003922	0.03932	0.03081	ORM1/TNFAIP3/ARG2/TWIST1/GHRL/LILRA4/GAS6/CX3CL1/ZC3H12A/IGF1/CD34/ACP5/TREM2/GPNMB/AKAP8/NR1H4/AXL/SYT11	18
BP	GO:0060395	SMAD protein signal transduction	18/2486	70/18670	0.003922	0.03932	0.03081	RBM14/INHBA/VEPH1/JUN/BTBD11/TGFB2/NUP93/TGFB1/SMAD1/BMP2/FOS/DAB2/WWTR1/INHBE/BMP8A/RBPMS/MAGI2/CILP	18
BP	GO:0031098	stress-activated protein kinase signaling cascade	59/2486	315/18670	0.003933	0.03936	0.03085	MMP8/MAPK11/TNF/DLG1/DUSP10/DNAJA1/TGFB2/CRKL/STRADB/PINK1/ZFP36/TRAF4/UBA52/ITCH/PPEF2/FCGR2B/ERN1/STK24/MAP3K14/ZC3H12A/IGF1R/BMP2/PTGER4/TRAF6/MAP3K2/EGFR/CYLD/SFRP2/SAMD5/MAP3K5/MAP3K1/TPD52L1/PLCB1/PAK4/TNFRSF11A/STK10/STK4/FZD10/MID1/IL1B/CCL21/SFRP1/FZD5/UBC/PDCD10/WNT5A/PAK3/TLR9/IL26/DUSP1/MAP3K3/LYN/SH2D3C/FZD4/CDC42EP5/CRYAB/PER1/CUL1/RASSF2	59
BP	GO:0042594	response to starvation	39/2486	191/18670	0.003955	0.03941	0.03089	RRAGA/PMAIP1/GABARAPL2/MAP1LC3A/PPARG/DEPDC5/EIF2AK4/JUN/FSTL1/PPM1D/ZFP36/IFI16/GAS6/EIF2S1/STK24/LARP1/ZC3H12A/SIRT1/SESN2/MAX/DDIT3/EIF2A/ULK2/TBL2/MAP3K5/CADPS2/CBL/KLF10/LRP11/SESN3/FOXK2/CPS1/SFRP1/USP33/MTOR/ADCYAP1/HSPA5/PDK4/HMGCL	39
BP	GO:0003283	atrial septum development	8/2486	21/18670	0.003963	0.03941	0.03089	ACVR1/TBX5/TGFB2/GJA5/MDM4/SMO/NOTCH2/ANK2	8
BP	GO:0032516	positive regulation of phosphoprotein phosphatase activity	8/2486	21/18670	0.003963	0.03941	0.03089	PPP1R15A/PPP1R15B/PDGFRB/MAGI2/CD300A/HSP90AB1/MTOR/PTPRC	8
BP	GO:1904469	positive regulation of tumor necrosis factor secretion	8/2486	21/18670	0.003963	0.03941	0.03089	ORM1/MMP8/LPL/DHX9/IFIH1/FZD5/WNT5A/FRMD8	8
BP	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	20/2486	81/18670	0.004049	0.0402	0.03151	CLU/SIRT2/KEAP1/SMAD7/ARIH2/HERPUD1/DAB2/CBFA2T3/ZFAND2A/VCP/CSNK1A1/RCHY1/PLK3/PLK1/IL33/RNF19B/CHFR/ARIH1/CAV1/TAF1	20
BP	GO:0050869	negative regulation of B cell activation	10/2486	30/18670	0.004092	0.04044	0.03169	INPP5D/TNFAIP3/PARP3/INHBA/FCGR2B/BTK/SFRP1/CD300A/LYN/RC3H1	10
BP	GO:0001701	in utero embryonic development	68/2486	373/18670	0.004094	0.04044	0.03169	ACVR1/POLB/MBNL1/KEAP1/PELO/GATA1/SYF2/BCOR/TWIST1/B9D1/ZFAT/TPM1/LPAR6/HES1/CDKN1C/NXN/FLCN/JAG2/TM4SF1/FOXC1/BMP2/WDR19/SP3/TRAF6/EGFR/BCL2L1/EMG1/NOS3/SKIL/IGF1/VASH1/PTH1R/MFNG/PDGFRA/STK4/NR2F2/SMO/RSPO3/HCFC1/TIE1/NOTCH1/NSUN2/GLI3/MYH9/OTUD7B/C2CD3/ZFPM2/FZD5/BPTF/ELL/WDTC1/MSX1/BYSL/CMTM3/PCGF2/MAN2A1/TMEM231/MYH10/PALB2/E2F8/SPINT2/JUNB/SOX6/SETD2/SIN3A/NEK2/ZNF830/NCOA1	68
BP	GO:0014745	negative regulation of muscle adaptation	6/2486	13/18670	0.004111	0.04044	0.03169	NOL3/NOS3/IGFBP5/KLF4/MIR214/MTOR	6
BP	GO:0033127	regulation of histone phosphorylation	6/2486	13/18670	0.004111	0.04044	0.03169	AKAP8L/TWIST1/CDK9/IL1B/AKAP8/RPS6KA5	6
BP	GO:1902894	negative regulation of pri-miRNA transcription by RNA polymerase II	6/2486	13/18670	0.004111	0.04044	0.03169	YY1/NFIB/NFATC4/RELA/SOX9/NFATC3	6
BP	GO:0003158	endothelium development	29/2486	132/18670	0.004118	0.04044	0.03169	ACVR1/HOXB5/CLDN5/MYADM/PROC/TNF/KDM6B/PDE2A/NRP1/GJA5/MIR21/RAPGEF3/GJA4/COL18A1/STC1/PDPN/MSN/PTN/CEACAM1/NR2F2/CD34/NOTCH1/IL1B/APOLD1/TJP1/CDH5/KDR/ADAMTS12/FOXJ2	29
BP	GO:0006613	cotranslational protein targeting to membrane	25/2486	109/18670	0.004119	0.04044	0.03169	SEC62/RPS27/RPS28/SEC61B/RPS15/UBA52/RPS26/RPLP1/RPL28/RPS3A/SSR1/RPL10/RPL29/TRAM1L1/RPS8/RPS4Y1/RPS2/RPL39/RPS10/RPL6/RPL14/RPS7/SRP54/RPL9/RPL15	25
BP	GO:0002699	positive regulation of immune effector process	43/2486	216/18670	0.004192	0.04084	0.03201	FAM49B/CD1C/PDPK1/CD177/FADD/ARG1/TRIM6/TNF/BCL10/IL1R1/CD244/TGFB1/FBXO38/STXBP1/MIR21/CD1B/NFKBIZ/DDX21/HLX/BTK/EXOSC3/TRAF6/IL23R/VAV1/P2RX7/C12orf4/HLA-B/IL13RA2/IL12A/IL2/TNFRSF14/IL1B/STX4/IL33/FZD5/WNT5A/TLR9/CD300A/LYN/PTPRC/RSAD2/HLA-A/ZCCHC3	43
BP	GO:0030048	actin filament-based movement	30/2486	138/18670	0.004197	0.04084	0.03201	SRI/SCN1B/TMOD1/MYL6B/WASF2/MYL4/DLG1/TPM1/GJA5/PDE4B/SGCD/JUP/KCND3/FNBP1L/STC1/PDPN/KCNA5/NUP155/EMP2/MYO1C/KCNJ8/MYH9/ANK2/FLNA/RYR2/CAV1/MYH10/DMD/SUN2/PARVA	30
BP	GO:0061008	hepaticobiliary system development	30/2486	138/18670	0.004197	0.04084	0.03201	CIT/TNFAIP3/ARG1/NIPBL/TAF10/JUN/LIMS2/TGFB1/HES1/RHBDD3/FBXW7/CCND1/HLX/SP3/EGFR/RELA/PTN/ASS1/CEACAM1/SOX9/NOTCH1/JARID2/GLI3/CPS1/ALDH1A2/HMGCS1/MAN2A1/ITGA2/E2F8/HMGCL	30
BP	GO:0002693	positive regulation of cellular extravasation	7/2486	17/18670	0.004219	0.04084	0.03201	FADD/ITGA4/IL1R1/ELANE/PLVAP/THY1/XG	7
BP	GO:0003184	pulmonary valve morphogenesis	7/2486	17/18670	0.004219	0.04084	0.03201	HEYL/TGFB2/GJA5/NOS3/NOTCH1/NOTCH2/SLIT2	7
BP	GO:0021783	preganglionic parasympathetic fiber development	7/2486	17/18670	0.004219	0.04084	0.03201	NAV2/PLXNA3/HES1/NRP1/ADARB1/SIX1/TBX1	7
BP	GO:0048535	lymph node development	7/2486	17/18670	0.004219	0.04084	0.03201	POLB/FADD/TGFB1/PDPN/TNFRSF11A/CD248/RC3H1	7
BP	GO:0050884	neuromuscular process controlling posture	7/2486	17/18670	0.004219	0.04084	0.03201	FXN/ADARB1/CLN8/GCH1/TMEM150C/POU4F1/PRRT2	7
BP	GO:0071360	cellular response to exogenous dsRNA	7/2486	17/18670	0.004219	0.04084	0.03201	DHX9/PQBP1/IFIH1/IFIT1/COLEC12/CAV1/ZCCHC3	7
BP	GO:1902105	regulation of leukocyte differentiation	52/2486	272/18670	0.004262	0.0412	0.03229	C1QC/INPP5D/FADD/INHBA/PPP2R3C/CSF1/PGLYRP1/IRF1/TNF/SMAD7/JUN/HOXA7/DUSP10/LTF/TGFB1/TAL1/PRDX2/CREB1/GAS6/FBXW7/CYP26B1/FCGR2B/CD83/MIR21/ZC3H12A/IRF4/NFKBIZ/HLX/FOS/BTK/TRAF6/IL23R/CYLD/MIR17HG/CEACAM1/KLF10/IL12A/IL2/POU4F1/NOTCH2/GLI3/SFRP1/TREM2/TLR9/HCLS1/MTOR/LYN/FBN1/RC3H1/PTPRC/AXL/RASSF2	52
BP	GO:1904375	regulation of protein localization to cell periphery	26/2486	115/18670	0.004274	0.04121	0.0323	PDPK1/CLIP3/SQSTM1/TNF/DLG1/TGFB1/STX8/GPC4/DAB2/EGFR/BCL2L1/STAC/ITGA3/STAC2/GPC6/GRASP/RAMP3/PLK1/STX4/SORBS1/TREM2/ARHGEF16/LRRC15/PKDCC/EPHB2/MRAP2	26
BP	GO:0031396	regulation of protein ubiquitination	41/2486	204/18670	0.004277	0.04121	0.0323	PEF1/TNFAIP3/FEM1A/SMAD7/BCL10/DNAJA1/PINK1/CDK9/MTBP/HERPUD1/NXN/RASSF5/FBXW7/HSP90AA1/UBXN1/FBXO4/TRAF6/UBE2S/DERL1/MTA1/PRR7/RPS2/RCHY1/PLK1/DTX3L/UBE2C/CAMLG/WDR70/SKP2/FAM107A/CHFR/HSP90AB1/CAV1/RPS7/MTOR/TAF1/WFS1/HSPA5/MYCBP2/PIN1/TRIM44	41
BP	GO:0051893	regulation of focal adhesion assembly	16/2486	60/18670	0.004325	0.04148	0.03251	ARHGAP6/LDB1/NRP1/CLASP2/COL16A1/PHLDB2/TEK/SFRP1/THY1/LIMS1/PPM1F/FAM107A/CLASP1/DLC1/KDR/LIMCH1	16
BP	GO:0090109	regulation of cell-substrate junction assembly	16/2486	60/18670	0.004325	0.04148	0.03251	ARHGAP6/LDB1/NRP1/CLASP2/COL16A1/PHLDB2/TEK/SFRP1/THY1/LIMS1/PPM1F/FAM107A/CLASP1/DLC1/KDR/LIMCH1	16
BP	GO:0030500	regulation of bone mineralization	19/2486	76/18670	0.004331	0.04148	0.03251	ACVR1/GATA1/BCOR/TMEM119/TWIST1/LTF/TGFB1/BMP2/FBN2/ECM1/P2RX7/ACVR2A/PTN/SOX9/ANKH/DDR2/PKDCC/KL/MGP	19
BP	GO:0060411	cardiac septum morphogenesis	19/2486	76/18670	0.004331	0.04148	0.03251	ACVR1/HEYL/TBX5/SMAD7/TGFB2/HES1/NRP1/GJA5/NOS3/MIR17HG/SMO/TBX2/NOTCH1/NOTCH2/ZFPM2/WNT5A/TBX1/SLIT2/PARVA	19
BP	GO:1990138	neuron projection extension	35/2486	168/18670	0.004382	0.0419	0.03284	NRCAM/CTTN/ITGA4/SEMA3B/RNF6/PLXNA3/BCL11A/EIF2AK4/SEMA3G/NRP1/L1CAM/RAPH1/HSP90AA1/FN1/SEMA4D/ULK2/CXCL12/SEMA6D/SEMA5B/ITSN2/MAP2/WASF1/DCLK1/PLXNA1/PPP3CB/CDK5R1/WNT5A/NDN/HSP90AB1/SLIT2/POSTN/SEMA3E/SLIT1/SIN3A/GDI1	35
BP	GO:0003203	endocardial cushion morphogenesis	11/2486	35/18670	0.004429	0.04206	0.03297	ACVR1/HEYL/TWIST1/TGFB2/BMP2/MDM4/NOS3/SOX9/TBX2/NOTCH1/MSX1	11
BP	GO:0003230	cardiac atrium development	11/2486	35/18670	0.004429	0.04206	0.03297	ACVR1/TBX5/TGFB2/GJA5/MDM4/SMO/NOTCH1/SHOX2/NOTCH2/ANK2/WNT5A	11
BP	GO:0045070	positive regulation of viral genome replication	11/2486	35/18670	0.004429	0.04206	0.03297	STOM/ADARB1/SRPK2/PPID/LARP1/IFIT1/NOTCH1/PKN2/CNOT7/STAU1/NR5A2	11
BP	GO:0048333	mesodermal cell differentiation	11/2486	35/18670	0.004429	0.04206	0.03297	ITGB3/INHBA/TAL1/KDM6B/SMAD1/SFRP2/ITGA3/KLF4/HOXA11/SIX2/ITGA2	11
BP	GO:0072659	protein localization to plasma membrane	50/2486	260/18670	0.004433	0.04206	0.03297	TTC7B/FGF13/SLC9A3R1/GRIP1/PDPK1/MPP5/BAG4/MYADM/SLC4A1/CLIP3/RAB13/SQSTM1/TNF/DLG1/TGFB1/STX8/PACSIN1/CACNB3/GAS6/CLASP2/STXBP1/GRIP2/EHD2/DAB2/JUP/EGFR/BCL2L1/STAC/SEC16A/ITGA3/STAC2/BBS1/RAMP2/ANK1/GRASP/RAMP3/TSPAN14/EMP2/STX4/SORBS1/TREM2/ARHGEF16/ANK2/LRRC15/FLNA/SYS1/PKDCC/RAB8A/EPHB2/MRAP2	50
BP	GO:0002011	morphogenesis of an epithelial sheet	15/2486	55/18670	0.004486	0.04251	0.03331	MPP5/PHACTR4/CLASP2/PDPN/CEACAM1/PHLDB2/COL5A1/NOTCH1/PDCD10/RREB1/WNT5A/FLNA/MTOR/CLASP1/CD151	15
BP	GO:0048871	multicellular organismal homeostasis	85/2486	485/18670	0.004507	0.04257	0.03337	ITGB3/GRB10/ADCY3/INPP5D/TNFAIP3/EDNRB/GATA1/APC/CSF1/LIPA/PRKAR2A/TUB/TMEM119/ADCY7/TNF/FABP5/LTF/GHRL/LDB1/CYP4F2/LCN2/ADCY4/KDM6B/CYP26B1/FLCN/ABCA4/IGF1R/IRF4/FOXC1/GPR3/CLN8/IRX3/SPP1/DDIT3/TRAF6/WWTR1/MDM1/EGFR/NOS3/HSPB1/ADCY6/P2RX7/ADIPOR2/HOXC10/ACOT13/PIGR/PTH1R/BBS1/TNFRSF11A/NR1D2/SMO/AQP1/AMPD2/MFAP2/HAS2/BSCL2/SOX9/BMP8A/CD34/NOTCH1/DIO2/ACP5/SERPINA3/YAP1/CIB2/IL1B/MUC2/ZNF423/OXTR/NOX4/TLR9/NDN/EBF2/CAV1/SLC35D3/ADCYAP1/WFS1/PRKAR2B/PDK4/BARD1/CORO1A/MRAP2/ABAT/LPCAT1/ZNF830	85
BP	GO:0050727	regulation of inflammatory response	85/2486	485/18670	0.004507	0.04257	0.03337	CLU/PROS1/C1QB/C1QA/SUCNR1/C1QC/MMP8/CR1L/TNFAIP3/EDNRB/CFH/PPARG/C5orf30/PROC/SPATA2/NFKBIA/FEM1A/SNCA/PGLYRP1/ADCY7/TNF/DUSP10/LPL/GHRL/CD59/IL1R1/DHX9/ELANE/C2/CFB/PDE2A/RHBDD3/TNIP1/MGLL/FCGR2B/CX3CL1/MIR21/ZC3H12A/NFKBIZ/BTK/PTGER4/SERPING1/CALCRL/EGFR/CYLD/WFDC1/CFHR2/IGF1/RELA/NEAT1/CPN1/MMP3/TNFRSF11A/MMP9/AGTR1/OSMR/NR1D2/IL2/C1R/KLF4/NUPR1/ACP5/IL1B/PLA2G2A/TEK/IL17D/IL33/TREM2/NLRP1/WNT5A/TLR9/TBC1D23/CDH5/LYN/C1S/ADCYAP1/CFI/ITGA2/A2M/ADAMTS12/PER1/PTPRC/NR1H4/CCL18/NLRP7	85
BP	GO:0002931	response to ischemia	14/2486	50/18670	0.0046	0.04332	0.03396	FAIM2/ARID1B/CSF1/SQSTM1/NOL3/PINK1/HYOU1/CX3CL1/P2RX7/UCHL1/MAP3K5/TREM2/REST/CAV1	14
BP	GO:0010718	positive regulation of epithelial to mesenchymal transition	14/2486	50/18670	0.0046	0.04332	0.03396	ACVR1/TWIST1/TGFB2/TGFB1/MIR21/FOXC1/BMP2/DAB2/WWTR1/PDPN/TGFB1I1/NOTCH1/IL1B/MTOR	14
BP	GO:0007224	smoothened signaling pathway	29/2486	133/18670	0.004612	0.04337	0.03399	GAS8/EVC/B9D1/GAS1/HIPK1/HES1/EVC2/BOC/CREBBP/WDR11/WDR19/WNT9A/TTBK2/CDON/SMO/GLIS2/PRRX1/IFT140/SHOX2/GLI3/SFRP1/C2CD3/FKBP8/DZIP1/SSNA1/TMEM17/IFT81/INTU/TMEM231	29
BP	GO:0032092	positive regulation of protein binding	22/2486	93/18670	0.004642	0.04357	0.03415	EP300/BDNF/PPP2CA/SPPL3/TRAF4/NRP1/ACE/BMP2/DERL1/MFNG/MMP9/STK4/DTX3L/CTHRC1/WNT5A/USP33/HSP90AB1/CAV1/TAF1/SPON1/HOXA3/PIN1	22
BP	GO:0032570	response to progesterone	13/2486	45/18670	0.004647	0.04357	0.03415	FOSB/TGFB2/TGFB1/FOS/RELA/CATSPER3/PTN/RAMP2/YAP1/OXTR/NCOA2/CAV1/NCOA1	13
BP	GO:0031333	negative regulation of protein complex assembly	30/2486	139/18670	0.004686	0.04386	0.03438	CLU/SIRT2/EPS8/TMOD1/MYADM/EP300/CLIP3/SNCA/FKBP4/SORL1/STXBP1/RAF1/PTGER4/AVIL/MAP2/PFN4/LMOD1/PPM1A/CAPZA1/TMSB4Y/TMSB15A/MIR214/CDH5/SLIT2/KANK3/STYXL1/PFN1/CRYAB/PRRT2/KIF14	30
BP	GO:0072331	signal transduction by p53 class mediator	51/2486	267/18670	0.004696	0.04386	0.03438	MUC1/PHF20/PMAIP1/CRADD/CNOT8/CNOT4/EP300/RPS27L/MAPK11/TAF4/TAF10/TWIST1/USP10/PPM1D/HIPK1/IFI16/PHLDA3/MIR21/TPX2/EXO1/BDKRB2/USP28/SIRT1/MDM4/SESN2/TRIM24/BATF/PML/HNRNPK/TAF3/PLK3/BANP/POU4F1/NUPR1/PRKAG2/BTG2/CDK5R1/MSX1/CNOT7/TP53BP2/CHD5/MAPKAPK5/RPS7/TRIAP1/TNKS1BP1/TAF1/E2F8/BARD1/CNOT1/PIN1/ING5	51
BP	GO:0046209	nitric oxide metabolic process	20/2486	82/18670	0.004699	0.04386	0.03438	CLU/HBB/DDAH1/MMP8/ARG2/TNF/HSP90AA1/ZC3H12A/GCH1/NOS3/ASS1/KLF4/CD34/ACP5/IL1B/CPS1/HSP90AB1/CAV1/MTOR/NQO1	20
BP	GO:0035966	response to topologically incorrect protein	40/2486	199/18670	0.004719	0.04398	0.03447	CLU/PPP1R15A/PPP1R15B/MBTPS1/EDEM1/EP300/SDF2L1/HSP90B1/DNAJA1/KLHL15/SERP1/HYOU1/HERPUD1/EIF2S1/CCND1/ERN1/HSP90AA1/DNAJB14/SSR1/DDX11/THBS4/DDIT3/TM7SF3/HSPB1/DERL1/SERPINH1/TBL2/VCP/CREB3L1/STT3B/KDELR3/HSP90AB1/STC2/BAK1/HSPB3/WFS1/HSPA5/SDF2/HSPB8/HSPA9	40
BP	GO:0002230	positive regulation of defense response to virus by host	9/2486	26/18670	0.004798	0.04438	0.03478	TRIM6/EIF2AK4/PARP9/ZC3H12A/PQBP1/IL23R/DTX3L/SIN3A/TRIM44	9
BP	GO:0003171	atrioventricular valve development	9/2486	26/18670	0.004798	0.04438	0.03478	ACVR1/HEYL/TBX5/TWIST1/TGFB2/GJA5/BMP2/MDM4/NOTCH1	9
BP	GO:0048843	negative regulation of axon extension involved in axon guidance	9/2486	26/18670	0.004798	0.04438	0.03478	SEMA3B/PLXNA3/SEMA3G/NRP1/SEMA4D/SEMA6D/SEMA5B/WNT5A/SEMA3E	9
BP	GO:0051497	negative regulation of stress fiber assembly	9/2486	26/18670	0.004798	0.04438	0.03478	ARHGAP6/WASF2/CLASP2/MIR21/PHLDB2/ARHGAP28/CLASP1/DLC1/PFN1	9
BP	GO:0072539	T-helper 17 cell differentiation	9/2486	26/18670	0.004798	0.04438	0.03478	SMAD7/MIR21/ZC3H12A/IRF4/NFKBIZ/IL23R/BATF/IL2/RC3H1	9
BP	GO:0010565	regulation of cellular ketone metabolic process	37/2486	181/18670	0.004813	0.04445	0.03484	PSMD14/PSMD12/PPTC7/PDPR/PPARG/SNCA/TWIST1/FABP5/PSMD7/PSMB5/ERLIN1/MIR21/BMP2/APOC1/SIRT1/ERLIN2/ADIPOR2/CEACAM1/IRS2/PDP1/PSMB7/PRKAG2/IL1B/PSMD1/PSMD9/REST/WDTC1/AZIN1/CAV1/MTOR/PSME1/PDK4/DKK3/NR1H4/FABP3/ELOVL5/NQO1	37
BP	GO:0051170	import into nucleus	34/2486	163/18670	0.004831	0.04445	0.03484	FAM53B/MBTPS1/RBM22/NFKBIA/NXT1/NUP93/IPO9/TGFB1/PHB2/HEATR3/IPO7/NOLC1/ZC3H12A/NUP50/KPNA1/JUP/PML/NUP153/GEMIN6/KPNA3/NUP188/SNRPB/NUP54/NUP214/SMO/NUP155/RPAIN/GLI3/TNPO3/IPO5/FLNA/SIX2/HCLS1/KPNA4	34
BP	GO:0006403	RNA localization	45/2486	230/18670	0.004834	0.04445	0.03484	SRRM1/NXF3/EIF5A/TOMM20/YY1/NXT1/AKAP8L/YTHDC1/SARNP/SFPQ/NUP93/DHX9/RPS15/THOC2/ZFP36/U2AF1L4/DDX19A/DCP2/NUP50/G3BP2/EXOSC3/SLBP/NUP153/U2AF1/NUP210/PABPN1/RAE1/NUP188/NUP160/NUP54/NXF1/NUP214/CCT8/NUP155/MYO1C/MRPL18/MCM3AP/KHDRBS1/SMG6/ARC/RFTN2/POLR2D/ABCE1/SETD2/NHP2	45
BP	GO:2001234	negative regulation of apoptotic signaling pathway	45/2486	230/18670	0.004834	0.04445	0.03484	CLU/MUC1/CTTN/ACVR1/FAIM2/TNFAIP3/FADD/GATA1/BDNF/SLC25A5/TNF/FXN/NOL3/DNAJA1/STRADB/PINK1/PRDX2/HYOU1/HERPUD1/NRP1/CX3CL1/MIR21/RAF1/BDKRB2/ITPRIP/SIRT1/BCL2L1/NME5/NOS3/HSPB1/SFRP2/IGF1/RELA/CXCL12/MMP9/MCL1/CREB3L1/IFI6/YAP1/IL1B/NONO/NR4A2/PCGF2/TRIAP1/WFS1	45
BP	GO:1905477	positive regulation of protein localization to membrane	27/2486	122/18670	0.004958	0.04552	0.03568	PMAIP1/PDPK1/STOM/CLIP3/MFF/SQSTM1/TNF/DLG1/TGFB1/SSH1/CACNB3/EGFR/STAC/ITGA3/YWHAZ/PTN/STAC2/RAMP3/MYO1C/STX4/SORBS1/TREM2/ARHGEF16/CDK5R1/TP53BP2/PDCD5/EPHB2	27
BP	GO:0071219	cellular response to molecule of bacterial origin	42/2486	212/18670	0.005042	0.04607	0.03611	SIRT2/CXCL5/TNFAIP3/EDNRB/CTSG/NFKBIB/IRF8/ARG1/NFKBIA/TNF/BCL10/LTF/TGFB1/LCN2/PRDX2/ZFP36/FCGR2B/CX3CL1/MIR21/ZC3H12A/PDE4B/CEBPE/TRAF6/NOS3/RELA/PLSCR4/ASS1/PABPN1/CXCL6/TFPI/PDCD1LG2/IL12A/IL1B/TREM2/FZD5/CXCL1/WNT5A/AKAP8/LYN/NR1H4/AXL/NLRP7	42
BP	GO:0006809	nitric oxide biosynthetic process	19/2486	77/18670	0.005047	0.04607	0.03611	CLU/HBB/DDAH1/MMP8/ARG2/TNF/HSP90AA1/ZC3H12A/GCH1/NOS3/ASS1/KLF4/CD34/ACP5/IL1B/HSP90AB1/CAV1/MTOR/NQO1	19
BP	GO:0016575	histone deacetylation	19/2486	77/18670	0.005047	0.04607	0.03611	SIRT2/RBM14/AKAP8L/NIPBL/SFPQ/TGFB1/PINK1/BRMS1L/SIRT1/MTA1/MORF4L2/PRDM5/REST/SUDS3/SIRT7/AKAP8/SIN3B/PER1/SIN3A	19
BP	GO:1901224	positive regulation of NIK/NF-kappaB signaling	19/2486	77/18670	0.005047	0.04607	0.03611	TRIP6/CHI3L1/MMP8/EP300/TNF/PTP4A3/TRAF4/TRAF6/EGFR/SAMD5/RELA/CARD10/IL1B/TREM2/LIMS1/TLR9/RC3H1/ZFP91/TRIM44	19
BP	GO:0031346	positive regulation of cell projection organization	69/2486	383/18670	0.005137	0.04682	0.0367	SCN1B/EPS8/GRIP1/NAV3/EP300/ARF1/BDNF/TRAK1/APC/PLXNA3/WASF2/CUX2/AKIRIN1/AGRN/RND2/LCN2/PLEK2/ANLN/PACSIN1/NRP1/L1CAM/FBXO38/FBXW8/CX3CL1/MIR21/P2RY12/FN1/ARHGEF7/NTRK2/FNBP1L/AVIL/SEMA4D/P2RX7/OBSL1/SKIL/CXCL12/CEP135/ITGA3/ITSN2/PTN/NIN/DPYSL3/IL2/SHOX2/PLXNA1/FKBP1B/CCL21/ENPP2/NCKAP1/RREB1/WNT5A/PAK3/DZIP1/MAGI2/ARPC2/SLIT2/MTOR/LYN/ADCYAP1/ITGA2/FZD4/STYXL1/PFN1/HSPA5/CDC42EP5/DOCK11/SHANK3/EPS8L1/GDI1	69
BP	GO:0035023	regulation of Rho protein signal transduction	30/2486	140/18670	0.005222	0.04746	0.0372	EPS8/SCAI/ARHGEF37/LPAR6/KANK2/AKAP13/NRP1/FLCN/RAF1/GPR4/ARHGEF7/FGD5/VAV1/LPAR4/GPR35/ITGA3/PLEKHG5/ITSN2/FARP1/PDGFRB/ARHGEF16/VAV3/FGD3/P2RY8/SOS2/DLC1/TNFAIP1/ARHGEF12/ARHGEF15/EPS8L1	30
BP	GO:1903364	positive regulation of cellular protein catabolic process	30/2486	140/18670	0.005222	0.04746	0.0372	CLU/SIRT2/TNFAIP3/KEAP1/EDEM1/SMAD7/ARIH2/HERPUD1/FBXW7/HSP90AA1/DAB2/ECSCR/CBFA2T3/ZFAND2A/MSN/EGF/VCP/CSNK1A1/RCHY1/PLK3/PLK1/NUPR1/IL33/TREM2/RNF139/RNF19B/CHFR/ARIH1/CAV1/TAF1	30
BP	GO:0031345	negative regulation of cell projection organization	38/2486	188/18670	0.00525	0.04764	0.03734	SPRY2/MYLIP/FGF13/PTPRO/SEMA3B/RGMA/RNF6/PLXNA3/BCL11A/RAP1GAP2/RTN4RL1/FKBP4/SEMA3G/NRP1/CRMP1/NFATC4/SPP1/SEMA4D/ADCY6/ULK2/ITGA3/SEMA6D/SEMA5B/MAP2/DPYSL3/LRIG2/EFNB2/PTPRG/CCL21/THY1/CDK5R1/WNT5A/MIR214/SLIT2/INPP5F/SEMA3E/EPHB2/GDI1	38
BP	GO:0042542	response to hydrogen peroxide	31/2486	146/18670	0.005273	0.04771	0.03739	HBB/MAP1LC3A/PPP1R15B/TNFAIP3/ARG1/JUN/FXN/PINK1/LCN2/KDM6B/STK24/MIR21/SMPD3/PYCR1/SIRT1/MAP3K5/RELA/HP/KCNA5/AQP1/KLF4/PDGFRB/FKBP1B/PDCD10/DUSP1/PCGF2/BAK1/KPNA4/CRYAB/AXL/NQO1	31
BP	GO:0051250	negative regulation of lymphocyte activation	31/2486	146/18670	0.005273	0.04771	0.03739	INPP5D/TNFAIP3/ARG2/PARP3/ARG1/INHBA/PGLYRP1/IRF1/SMAD7/DLG1/TGFB1/PRDX2/RHBDD3/FCGR2B/TWSG1/MIR21/ZC3H12A/HLX/BTK/CEACAM1/PDCD1LG2/IL2/TNFRSF14/GLI3/SFRP1/GPNMB/CD300A/LYN/SPN/RC3H1/AXL	31
BP	GO:0050796	regulation of insulin secretion	36/2486	176/18670	0.005311	0.04789	0.03754	SRI/LRP5L/SYTL4/ITPR1/CDK16/SLC25A5/CACNA2D2/TNF/GHRL/SERP1/TRH/PFKFB2/C2CD2L/ICA1/ADRA2A/RAPGEF3/JAGN1/TM7SF3/SLC25A6/IRS2/KCNA5/BMP8A/IL1B/STX4/FKBP1B/SFRP1/PPP3CB/PSMD9/REST/CAPN10/KCNS3/MIDN/NR1H4/LRP5/RAPGEF4/ABAT	36
BP	GO:0001558	regulation of cell growth	74/2486	416/18670	0.00532	0.04789	0.03754	NRCAM/CTTN/FGF13/SERTAD2/PPARG/YY1/KIF26A/SEMA3B/INHBA/SLC25A33/BDNF/RNF6/PLXNA3/BCL11A/FXN/PPP2CA/TGFB2/CRKL/TGFB1/SERTAD3/RND2/SEMA3G/NRP1/L1CAM/ITCH/CDKN2C/FLCN/FN1/SIRT1/SESN2/SPP1/EGFR/KIAA1109/SFRP2/SEMA4D/PML/KAZALD1/WFDC1/ULK2/IGF1/CXCL12/ADIPOR2/SEMA6D/SEMA5B/ITSN2/IGFBP4/PAK4/CEACAM1/MAP2/IGFBP5/AGTR1/IL2/BCAR1/SFRP1/CRLF3/CDK5R1/WNT5A/FAM107A/MSX1/SLIT2/MTOR/SEMA3E/PRSS2/N6AMT1/CRYAB/LTBP4/RERG/HYAL1/SIN3A/KIF14/IGFBP3/PIN1/OSGIN2/GDI1	74
BP	GO:0043433	negative regulation of DNA-binding transcription factor activity	35/2486	170/18670	0.005328	0.04789	0.03754	SRI/TNFAIP3/KEAP1/HEYL/NFKBIA/EIF2AK4/TWIST1/SMAD7/NFKBIE/PHB2/PRDX2/BHLHE40/TRIM21/GAS6/ITCH/ZC3H12A/MED13/G3BP2/USP7/SIRT1/DDIT3/CYLD/TAF3/FOXS1/SFRP4/GLIS2/KLF4/RLIM/NUPR1/FLNA/TLR9/TAF1/WFS1/NR1H4/ADORA3	35
BP	GO:0010543	regulation of platelet activation	10/2486	31/18670	0.005332	0.04789	0.03754	SH2B3/CD9/SELP/NOS3/PDPN/PDGFRA/CEACAM1/C1QTNF1/LYN/ABAT	10
BP	GO:0034694	response to prostaglandin	10/2486	31/18670	0.005332	0.04789	0.03754	PPARG/YY1/PTGER4/ADCY6/PTGFR/AKR1C2/CCL21/SFRP1/AKAP8/TNC	10
BP	GO:1903078	positive regulation of protein localization to plasma membrane	15/2486	56/18670	0.005388	0.04833	0.03788	PDPK1/CLIP3/SQSTM1/TNF/DLG1/EGFR/STAC/ITGA3/STAC2/RAMP3/STX4/SORBS1/TREM2/ARHGEF16/EPHB2	15
BP	GO:0032272	negative regulation of protein polymerization	18/2486	72/18670	0.005402	0.04839	0.03792	EPS8/TMOD1/MYADM/CLIP3/SNCA/FKBP4/AVIL/MAP2/PFN4/LMOD1/CAPZA1/TMSB4Y/TMSB15A/MIR214/CDH5/SLIT2/KANK3/PFN1	18
BP	GO:0019216	regulation of lipid metabolic process	73/2486	410/18670	0.005483	0.04893	0.03835	SOCS7/ORMDL1/PDPR/MBTPS1/FHL2/PPARG/ME1/ARF1/RGL1/SNCA/TNF/TWIST1/FLT1/FABP5/SCT/TGFB1/SORL1/CREB1/FBXW7/ERLIN1/ADRA2A/SMPD3/CREBBP/NFYA/P2RY12/BMP2/APOC1/ANGPTL4/SIRT1/RARRES2/ERLIN2/ADIPOR2/GNB3/PDGFRA/CCDC3/CEACAM1/IRS2/AGTR1/NR1D2/PDP1/KLF4/PDGFRB/BSCL2/PRKAG2/SERPINA3/IL1B/TEK/CCL21/SORBS1/WDR91/REST/VAV3/NCOA2/WDTC1/ORMDL2/HMGCS1/CAV1/DGKZ/MTOR/LYN/SIN3B/ALAS1/PDK4/MTMR4/NCOA6/DKK3/NR1H4/FABP3/SIN3A/ELOVL5/LPCAT1/NCOA1/CHD9	73
BP	GO:0002793	positive regulation of peptide secretion	54/2486	288/18670	0.005491	0.04893	0.03835	SRI/ORM1/SYTL4/MMP8/MBP/ARF1/MAPK11/TRIM6/TNF/TWIST1/LPL/GHRL/TGFB2/SCT/FRMD4A/VEGFC/DHX9/CD244/TGFB1/SERP1/TRH/PFKFB2/C2CD2L/PPID/PTGER4/TM7SF3/EGFR/IFIH1/P2RX7/IGF1/IRS2/IL2/TNFRSF14/CD34/IL1B/STX4/IL33/TREM2/PPP3CB/PSMD9/FZD5/NLRP1/WNT5A/IL26/PARD6A/CAPN10/POSTN/ADCYAP1/FRMD8/MYH10/UNC13B/NR1H4/ABAT/NLRP7	54
BP	GO:0035584	calcium-mediated signaling using intracellular calcium source	8/2486	22/18670	0.00551	0.04893	0.03835	SELP/GPR143/PTGFR/FKBP1B/RYR2/KDR/DEFB1/PTPRC	8
BP	GO:0071359	cellular response to dsRNA	8/2486	22/18670	0.00551	0.04893	0.03835	DHX9/PQBP1/IFIH1/P2RX7/IFIT1/COLEC12/CAV1/ZCCHC3	8
BP	GO:0071379	cellular response to prostaglandin stimulus	8/2486	22/18670	0.00551	0.04893	0.03835	PPARG/PTGER4/ADCY6/PTGFR/AKR1C2/SFRP1/AKAP8/TNC	8
BP	GO:0097205	renal filtration	8/2486	22/18670	0.00551	0.04893	0.03835	PTPRO/GAS6/GJA5/ITGA3/SULF1/EMP2/CD34/MCAM	8
BP	GO:0030073	insulin secretion	41/2486	207/18670	0.005564	0.04934	0.03867	SRI/LRP5L/SYTL4/CAMK2G/ITPR1/CDK16/SLC25A5/CACNA2D2/SNX19/TNF/GHRL/SERP1/TRH/PFKFB2/RAB11FIP5/C2CD2L/ICA1/ADRA2A/RAF1/RAPGEF3/JAGN1/TM7SF3/SLC25A6/IRS2/KCNA5/BMP8A/IL1B/STX4/FKBP1B/SFRP1/PPP3CB/PSMD9/REST/CAPN10/ADCYAP1/KCNS3/MIDN/NR1H4/LRP5/RAPGEF4/ABAT	41
BP	GO:0051031	tRNA transport	11/2486	36/18670	0.005624	0.0498	0.03903	TOMM20/NUP93/NUP50/NUP153/NUP210/RAE1/NUP188/NUP160/NUP54/NUP214/NUP155	11
BP	GO:0006984	ER-nucleus signaling pathway	13/2486	46/18670	0.005704	0.05029	0.03942	PPP1R15A/PPP1R15B/MBTPS1/HSP90B1/HERPUD1/EIF2S1/FBXW7/ERLIN1/DDIT3/EIF2A/ERLIN2/WFS1/HSPA5	13
BP	GO:0031648	protein destabilization	13/2486	46/18670	0.005704	0.05029	0.03942	MYLIP/EP300/SNCA/TRIM21/FBXW7/CREBBP/BMP2/FBXO4/SIRT1/DERL1/PLK1/RNF139/CHFR	13
BP	GO:0032480	negative regulation of type I interferon production	13/2486	46/18670	0.005704	0.05029	0.03942	TNFAIP3/YY1/LILRA4/ITCH/GPATCH3/MIR21/REL/IFIH1/CYLD/RNF216/RNF125/PCBP2/PIN1	13
BP	GO:0001889	liver development	29/2486	135/18670	0.005749	0.05048	0.03957	CIT/TNFAIP3/ARG1/TAF10/JUN/LIMS2/TGFB1/HES1/RHBDD3/FBXW7/CCND1/HLX/SP3/EGFR/RELA/PTN/ASS1/CEACAM1/SOX9/NOTCH1/JARID2/GLI3/CPS1/ALDH1A2/HMGCS1/MAN2A1/ITGA2/E2F8/HMGCL	29
BP	GO:0043484	regulation of RNA splicing	29/2486	135/18670	0.005749	0.05048	0.03957	TRA2B/RBM4/MBNL1/RBM22/WTAP/CLK1/YTHDC1/FUS/RBM7/SRPK2/SF3B4/ERN1/RPS26/RBM3/ZBTB7A/PQBP1/RBMXL1/JMJD6/TRA2A/HNRNPK/CELF1/AHNAK/CLK3/ZC3H10/KHDRBS1/KHDRBS3/REST/RBMX/MBNL2	29
BP	GO:0007411	axon guidance	52/2486	276/18670	0.005753	0.05048	0.03957	GRB10/NRCAM/SCN1B/PTPRO/SEMA3B/BDNF/PLXNA3/AGRN/SEMA3G/NEXN/NRP1/L1CAM/BOC/NFIB/CRMP1/YTHDF1/SEMA4D/CXCL12/SEMA6D/SEMA5B/EPHB4/FLRT2/CHN1/IRS2/ROBO4/PIK3CD/EFNB2/SMO/FRS2/ENAH/GAP43/GLI3/PLXNA1/MATN2/GPC1/CDK5R1/WNT5A/USP33/IGSF9/SLIT2/NTN4/MYH10/SEMA3E/RPS6KA5/SLIT1/MYCBP2/DOK5/ETV1/EPHB2/GFRA1/SHANK3/DOK4	52
BP	GO:0043967	histone H4 acetylation	17/2486	67/18670	0.005758	0.05048	0.03957	MUC1/PHF20/MSL2/EP300/HAT1/ING3/WDR5/IRF4/TRRAP/SIRT1/MORF4L2/HCFC1/EP400/CHD5/EPC1/PER1/NCOA1	17
BP	GO:0097530	granulocyte migration	30/2486	141/18670	0.005809	0.05076	0.03978	CXCL5/CD177/CSF1/TGFB2/IL1R1/AKIRIN1/CX3CL1/CXCR1/PDE4B/PTGER4/EDN3/THBS4/JAGN1/CCL13/VAV1/RARRES2/ITGA9/DAPK2/CXCL6/PIK3CD/HRH1/IL1B/CCL21/CXCL1/VAV3/CCL8/CD300A/SLIT2/CCL18/XG	30
BP	GO:0045637	regulation of myeloid cell differentiation	48/2486	251/18670	0.005819	0.05076	0.03978	MYL9/KLF13/C1QC/INPP5D/FADD/CNOT4/INHBA/EP300/GATA1/NFKBIA/CSF1/PRKCB/TNF/JUN/HOXA7/TRIM58/LTF/TGFB1/TAL1/LDB1/CREB1/TNRC6B/ZFP36/FBXW7/WDR5/CREBBP/FOS/TRAF6/LOX/IL23R/MEIS2/ACVR2A/CEACAM1/KLF10/POU4F1/RAB7B/NOTCH2/SFRP1/TREM2/HCLS1/MTOR/LYN/HOXA9/FBN1/GP1BA/SIN3A/HSPA9/RASSF2	48
BP	GO:0072028	nephron morphogenesis	19/2486	78/18670	0.005858	0.05076	0.03978	IRX2/PBX1/DLG1/TGFB1/HES1/BMP2/IRX3/NPNT/SIX1/HOXB7/SMO/PDGFRB/SOX9/GLI3/HOXA11/ADAMTS16/SIX2/GZF1/LZTS2	19
BP	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	19/2486	78/18670	0.005858	0.05076	0.03978	MUC1/PMAIP1/EP300/RPS27L/HIPK1/IFI16/PHLDA3/MIR21/BDKRB2/USP28/SIRT1/PML/HNRNPK/POU4F1/NUPR1/MSX1/TP53BP2/RPS7/TRIAP1	19
BP	GO:0010944	negative regulation of transcription by competitive promoter binding	5/2486	10/18670	0.005871	0.05076	0.03978	MUC1/BHLHE41/SMAD7/CREB1/KDM2A	5
BP	GO:0033690	positive regulation of osteoblast proliferation	5/2486	10/18670	0.005871	0.05076	0.03978	GATA1/TMEM119/LTF/BMP2/CTHRC1	5
BP	GO:0036500	ATF6-mediated unfolded protein response	5/2486	10/18670	0.005871	0.05076	0.03978	MBTPS1/HSP90B1/DDIT3/WFS1/HSPA5	5
BP	GO:0097048	dendritic cell apoptotic process	5/2486	10/18670	0.005871	0.05076	0.03978	GAS6/CXCL12/CCL21/LYN/AXL	5
BP	GO:1902237	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	5/2486	10/18670	0.005871	0.05076	0.03978	PMAIP1/RNF183/SIRT1/DDIT3/SERINC3	5
BP	GO:2000668	regulation of dendritic cell apoptotic process	5/2486	10/18670	0.005871	0.05076	0.03978	GAS6/CXCL12/CCL21/LYN/AXL	5
BP	GO:0030336	negative regulation of cell migration	61/2486	334/18670	0.00604	0.05215	0.04088	SLC9A3R1/PPARG/C5orf30/NAV3/SCAI/TBX5/SMAD7/HOXA7/DUSP10/TGFB1/SRGAP1/TPM1/CYGB/ADARB1/CLASP2/STK24/CX3CL1/MIR21/FLCN/PTGER4/MMRN2/JUP/SFRP2/STC1/CXCL12/ADAMTS9/CARD10/SEMA6D/VASH1/PTN/PLCB1/PHLDB2/NR2F2/DNAJA4/IGFBP5/DPYSL3/SULF1/MEOX2/KLF4/TIE1/NOTCH1/PTPRG/CCL21/SFRP1/IL33/THY1/ANGPT2/PDCD10/MIR214/DCN/HAS1/MAGI2/DUSP1/CD300A/SLIT2/CLASP1/GPR173/DLC1/LIMCH1/IGFBP3/ADORA3	61
BP	GO:0031348	negative regulation of defense response	46/2486	239/18670	0.006052	0.05218	0.0409	SIRT2/TNFAIP3/ARG2/PPARG/HTRA1/C5orf30/ARG1/PROC/FEM1A/PGLYRP1/ADCY7/YTHDF2/DUSP10/GHRL/ELANE/IFI16/SAMHD1/ITCH/GPATCH3/FCGR2B/CX3CL1/MIR21/ZC3H12A/PTGER4/SERPING1/CALCRL/WFDC1/IGF1/TSPAN6/CEACAM1/NR1D2/IL2/KLF4/SERPINB9/ACP5/TEK/RNF125/YTHDF3/CDH5/CNOT7/ADCYAP1/PCBP2/A2M/PTPRC/NR1H4/NLRP7	46
BP	GO:0110020	regulation of actomyosin structure organization	22/2486	95/18670	0.006068	0.05218	0.0409	ARHGAP6/BAG4/WASF2/TPM1/AKAP13/NRP1/CLASP2/ASAP3/MIR21/RAPGEF3/PTGER4/PHLDB2/ARHGAP28/SFRP1/NOX4/PPM1F/MTOR/CLASP1/DLC1/PFN1/ARHGEF15/LIMCH1	22
BP	GO:0046824	positive regulation of nucleocytoplasmic transport	16/2486	62/18670	0.006105	0.05218	0.0409	RBM22/DHX9/TGFB1/GAS6/ZC3H12A/RAPGEF3/JUP/PPM1A/SMO/GLI3/IL1B/KHDRBS1/IPO5/FLNA/HCLS1/ANP32B	16
BP	GO:0006704	glucocorticoid biosynthetic process	7/2486	18/18670	0.006119	0.05218	0.0409	CYP11A1/BMP2/CYP21A2/HSD11B2/HSD11B1/REST/DKK3	7
BP	GO:0035994	response to muscle stretch	7/2486	18/18670	0.006119	0.05218	0.0409	NFKBIA/JUN/RAF1/FOS/RELA/RYR2/DMD	7
BP	GO:0048557	embryonic digestive tract morphogenesis	7/2486	18/18670	0.006119	0.05218	0.0409	NIPBL/RBPMS2/HLX/PDGFRA/SHOX2/GLI3/SIX2	7
BP	GO:0071318	cellular response to ATP	7/2486	18/18670	0.006119	0.05218	0.0409	HSP90B1/SSH1/P2RY12/P2RX7/P2RY2/CIB2/TAF1	7
BP	GO:0090330	regulation of platelet aggregation	7/2486	18/18670	0.006119	0.05218	0.0409	SH2B3/CD9/PDPN/CEACAM1/C1QTNF1/LYN/ABAT	7
BP	GO:2000319	regulation of T-helper 17 cell differentiation	7/2486	18/18670	0.006119	0.05218	0.0409	SMAD7/MIR21/ZC3H12A/NFKBIZ/IL23R/IL2/RC3H1	7
BP	GO:0097485	neuron projection guidance	52/2486	277/18670	0.006189	0.0527	0.0413	GRB10/NRCAM/SCN1B/PTPRO/SEMA3B/BDNF/PLXNA3/AGRN/SEMA3G/NEXN/NRP1/L1CAM/BOC/NFIB/CRMP1/YTHDF1/SEMA4D/CXCL12/SEMA6D/SEMA5B/EPHB4/FLRT2/CHN1/IRS2/ROBO4/PIK3CD/EFNB2/SMO/FRS2/ENAH/GAP43/GLI3/PLXNA1/MATN2/GPC1/CDK5R1/WNT5A/USP33/IGSF9/SLIT2/NTN4/MYH10/SEMA3E/RPS6KA5/SLIT1/MYCBP2/DOK5/ETV1/EPHB2/GFRA1/SHANK3/DOK4	52
BP	GO:0001736	establishment of planar polarity	27/2486	124/18670	0.006233	0.05293	0.04149	PSMD14/PSMD12/PLEKHA4/PSMD7/PSMB5/GPC4/DAB2/AP2A2/SFRP2/GPC6/SEC24B/RSPO3/PSMB7/CTHRC1/PSMD1/SFRP1/PSMD9/FZD5/WNT5A/ROR1/MAGI2/PARD6A/INTU/FZD4/PSME1/PFN1/PRICKLE2	27
BP	GO:0007164	establishment of tissue polarity	27/2486	124/18670	0.006233	0.05293	0.04149	PSMD14/PSMD12/PLEKHA4/PSMD7/PSMB5/GPC4/DAB2/AP2A2/SFRP2/GPC6/SEC24B/RSPO3/PSMB7/CTHRC1/PSMD1/SFRP1/PSMD9/FZD5/WNT5A/ROR1/MAGI2/PARD6A/INTU/FZD4/PSME1/PFN1/PRICKLE2	27
BP	GO:0050818	regulation of coagulation	20/2486	84/18670	0.006259	0.05308	0.0416	PROS1/SH2B3/PROC/CD9/PRDX2/SELP/SERPING1/NOS3/PDPN/TFPI/PDGFRA/CEACAM1/PLAT/C1QTNF1/CD34/FAP/CAV1/LYN/GP1BA/ABAT	20
BP	GO:0031532	actin cytoskeleton reorganization	23/2486	101/18670	0.00632	0.05341	0.04186	RHOBTB1/CTTN/EPS8/NTF3/TGFB1/CDC42BPA/PLEK2/NRP1/RAPGEF3/PDGFRA/WHAMM/BCAR1/NOTCH2/MYH9/TEK/NEDD9/FLNA/PDLIM4/CAPN10/HCLS1/EFS/SEMA3E/PARVA	23
BP	GO:0003231	cardiac ventricle development	28/2486	130/18670	0.006328	0.05341	0.04186	LTBP1/ACVR1/HEYL/TBX5/SMAD7/TGFB2/TGFB1/TPM1/PDE2A/HES1/GJA5/MATR3/FOXC1/LUZP1/MDM4/NOS3/SFRP2/CPE/UBE4B/MIR17HG/POU4F1/FRS2/NOTCH1/HECTD1/ZFPM2/WNT5A/RYR2/SLIT2	28
BP	GO:0043409	negative regulation of MAPK cascade	37/2486	184/18670	0.006346	0.05341	0.04186	SPRY2/SH2B3/SLC9A3R1/DLG1/DUSP10/PPP2CA/DNAJA1/PINK1/SORL1/SPRY1/PRDM15/ITCH/TNIP1/PPEF2/MIR21/FLCN/IGF1R/CYLD/SFRP2/P2RX7/SPRY4/UCHL1/TIMP3/KLF4/IL1B/SFRP1/FBLN1/DUSP1/CD300A/CAV1/LYN/DUSP18/RGS14/PER1/EPHB2/PTPRC/PIN1	37
BP	GO:0006884	cell volume homeostasis	9/2486	27/18670	0.00636	0.05341	0.04186	CLNS1A/SCT/LRRC8A/P2RX7/SLC12A8/GNB3/KCNMA1/AQP1/SHANK3	9
BP	GO:1902175	regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	9/2486	27/18670	0.00636	0.05341	0.04186	NOL3/SFPQ/PINK1/FBXW7/SIRT1/NME5/HSPB1/MCL1/NONO	9
BP	GO:0003012	muscle system process	81/2486	465/18670	0.006387	0.05341	0.04186	SRI/MYL9/SCN1B/CTTN/SLC6A8/ITGB5/CAMK2G/EDNRB/ARG2/TMOD1/YY1/MYL6B/MYL4/SMAD7/DLG1/NOL3/GHRL/CDK9/TPM1/ACTG2/AKAP13/TACR1/ADRA2A/GJA5/LMCD1/MIR21/ZC3H12A/CALD1/PDE4B/GRIP2/BDKRB2/SGCD/GTF2IRD1/EDN3/ASPH/JUP/CALCRL/KCND3/STAC/NOS3/STC1/NPNT/OBSL1/IGF1/STAC2/PABPN1/UTRN/MIR17HG/IGFBP5/KCNA5/LMOD1/SULF1/SSPN/KCNMA1/FXYD1/NUP155/KLF4/KCNJ8/NOTCH1/RCSD1/JARID2/KCNA1/IL1B/SMTN/FKBP1B/HSPB6/SORBS1/ANK2/OXTR/MIR214/FLNA/RYR2/CAV1/INPP5F/MTOR/ITGA2/DMD/ACTA2/CRYAB/PIN1/ABAT	81
BP	GO:0019081	viral translation	6/2486	14/18670	0.006392	0.05341	0.04186	EIF3L/EIF2AK4/DHX9/DENR/EIF3F/PCBP2	6
BP	GO:0020027	hemoglobin metabolic process	6/2486	14/18670	0.006392	0.05341	0.04186	ALAS2/EPB42/INHBA/LDB1/AHSP/KLF4	6
BP	GO:0060211	regulation of nuclear-transcribed mRNA poly(A) tail shortening	6/2486	14/18670	0.006392	0.05341	0.04186	TNRC6B/ZFP36/POLR2G/BTG2/CNOT7/CNOT1	6
BP	GO:0097202	activation of cysteine-type endopeptidase activity	6/2486	14/18670	0.006392	0.05341	0.04186	FADD/TBC1D10A/IFI16/ASPH/BAK1/CIDEB	6
BP	GO:2001044	regulation of integrin-mediated signaling pathway	6/2486	14/18670	0.006392	0.05341	0.04186	CD177/LIMS2/PHACTR4/EMP2/LIMS1/FLNA	6
BP	GO:0001755	neural crest cell migration	15/2486	57/18670	0.006431	0.05352	0.04195	ACVR1/EDNRB/SEMA3B/TWIST1/SEMA3G/PHACTR4/NRP1/FN1/EDN3/SEMA4D/SEMA6D/SEMA5B/SMO/TBX1/SEMA3E	15
BP	GO:0048008	platelet-derived growth factor receptor signaling pathway	15/2486	57/18670	0.006431	0.05352	0.04195	SLC9A3R1/SNCA/NRP1/TIPARP/SMPD3/LOX/PDGFRA/CSRNP1/CBL/PLAT/LRIG2/BCAR1/PDGFRB/PDGFRL/RGS14	15
BP	GO:0050819	negative regulation of coagulation	15/2486	57/18670	0.006431	0.05352	0.04195	PROS1/SH2B3/PROC/CD9/SERPING1/NOS3/TFPI/PDGFRA/CEACAM1/PLAT/C1QTNF1/CD34/FAP/GP1BA/ABAT	15
BP	GO:0030203	glycosaminoglycan metabolic process	33/2486	160/18670	0.006488	0.05392	0.04226	IDS/CHST1/B4GALT2/PGLYRP1/TGFB1/LYG2/AGRN/SMPD3/FOXC1/SDC2/GPC4/EGF/CHST3/GPC6/BGN/HS3ST2/PDGFRB/HAS2/IL1B/LYVE1/GPC1/HAS3/DCN/GALNT5/HAS1/ACAN/OGN/CSPG4/ITIH2/FMOD/PRELP/B4GALT4/HYAL1	33
BP	GO:0046849	bone remodeling	21/2486	90/18670	0.006607	0.05484	0.04298	ITGB3/LRP5L/INPP5D/TNFAIP3/TMEM119/TGFB1/SPP1/TRAF6/EGFR/P2RX7/PTN/PTH1R/TNFRSF11A/ACP5/NOTCH2/CTHRC1/SFRP1/NOX4/PDK4/LRP5/RASSF2	21
BP	GO:0032609	interferon-gamma production	25/2486	113/18670	0.00671	0.05562	0.04359	FAM49B/HLA-DPB1/FADD/IRF8/INHBA/PGLYRP1/TNF/IL1R1/CD244/CD276/GAS6/ZC3H12A/PDE4B/IL23R/PDCD1LG2/IL12A/IL2/IL1B/IL33/FZD5/WNT5A/TLR9/SPN/NR1H4/AXL	25
BP	GO:0002221	pattern recognition receptor signaling pathway	39/2486	197/18670	0.00678	0.05613	0.04399	PDPK1/TNFAIP3/OTUD4/FADD/NFKBIA/HSP90B1/PGLYRP1/IRF1/BCL10/LTF/LILRA4/UBA52/ITCH/TNIP1/GPATCH3/IRF4/BTK/TRAF6/IFIH1/CYLD/MAP3K1/RELA/TSPAN6/RAB7B/CNPY3/CD300LF/UBC/UBE2D3/RNF125/COLEC12/TLR9/CD300A/CAV1/LYN/TRIL/NR1H4/RSAD2/ALPK1/ZCCHC3	39
BP	GO:0048841	regulation of axon extension involved in axon guidance	10/2486	32/18670	0.006846	0.05643	0.04423	SEMA3B/PLXNA3/SEMA3G/NRP1/SEMA4D/CXCL12/SEMA6D/SEMA5B/WNT5A/SEMA3E	10
BP	GO:0060317	cardiac epithelial to mesenchymal transition	10/2486	32/18670	0.006846	0.05643	0.04423	ACVR1/HEYL/TWIST1/TGFB2/SPRY1/MIR21/BMP2/HAS2/NOTCH1/MSX1	10
BP	GO:0060325	face morphogenesis	10/2486	32/18670	0.006846	0.05643	0.04423	CLDN5/EP300/NIPBL/TGFB1/TIPARP/ASPH/PDGFRA/CSRNP1/MSX1/TBX1	10
BP	GO:0007173	epidermal growth factor receptor signaling pathway	26/2486	119/18670	0.006853	0.05643	0.04423	SPRY2/PDPK1/TGFB1/SPRY1/FBXW7/ADRA2A/MIR21/CHMP6/ARHGEF7/EGFR/RHBDF1/PIGR/EGF/CBL/CEACAM1/MMP9/DGKD/BCAR1/AFAP1L2/SOX9/IFI6/CAMLG/EFEMP1/PDE6G/RPS6KA5/RASSF2	26
BP	GO:0071478	cellular response to radiation	38/2486	191/18670	0.006864	0.05644	0.04424	C9orf116/GUCY2D/MME/XRCC6/YY1/POLE3/EP300/NIPBL/EIF2AK4/TGFB1/IFI16/EIF2S1/PPID/CREBBP/FBXO4/USP28/NFATC4/SIRT1/BCL2L1/SFRP2/PTN/BMF/AQP1/YAP1/SFRP1/NOX4/PPEF1/TRIAP1/BAK1/TNKS1BP1/METAP1/PDE6G/TAF1/MFAP4/HSPA5/MGMT/CRYAB/HYAL1	38
BP	GO:0048010	vascular endothelial growth factor receptor signaling pathway	22/2486	96/18670	0.006905	0.05661	0.04437	ITGB3/GRB10/MAPK11/WASF2/PRKCB/FLT1/VEGFC/NRP1/HSP90AA1/FOXC1/FGF18/MMRN2/VAV1/HSPB1/SULF1/BCAR1/IL1B/NCKAP1/VAV3/KDR/FZD4/AXL	22
BP	GO:2001169	regulation of ATP biosynthetic process	22/2486	96/18670	0.006905	0.05661	0.04437	NUP93/PINK1/PFKFB2/FLCN/ZBTB7A/NUP50/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/VCP/RAE1/NUP188/NUP160/NUP54/NUP214/NUP155/NUPR1/SLC2A6/PRKAG2/TREM2	22
BP	GO:1903037	regulation of leukocyte cell-cell adhesion	56/2486	304/18670	0.006912	0.05661	0.04437	FAM49B/PDPK1/HLA-DPB1/ARG2/FADD/ITGA4/ARG1/IRF1/TNF/SMAD7/DLG1/DUSP10/BCL10/TGFB1/IGFBP2/ELANE/PRDX2/CD276/HES1/FCGR2B/CD83/TWSG1/MIR21/ZC3H12A/NFKBIZ/HLX/TRAF6/IL23R/CYLD/VAV1/IGF1/RELA/CXCL12/ASS1/CEACAM1/PDCD1LG2/IL12A/EFNB2/IL2/KLF4/HAS2/TNFRSF14/GLI3/IL1B/CCL21/THY1/GPNMB/PAK3/CD300A/CAV1/LYN/SPN/RC3H1/PTPRC/CORO1A/DOCK8	56
BP	GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism	43/2486	222/18670	0.006926	0.05664	0.0444	IFI27/SLPI/STOM/ARG1/EP300/TRIM6/EIF2AK4/CAV2/TNF/JUN/LTF/DHX9/IFITM3/CDK9/TRIM21/ZFP36/IFI16/TNIP1/ADARB1/SRPK2/PPID/LARP1/CHD1/ZC3H12A/ILF3/PML/POLR2G/CXCL6/VPS37B/RSF1/IFIT1/IFIT5/NOTCH1/IFITM2/PKN2/REST/CCL8/CNOT7/CAV1/POLR2D/STAU1/RSAD2/NR5A2	43
BP	GO:0010799	regulation of peptidyl-threonine phosphorylation	13/2486	47/18670	0.006943	0.05664	0.0444	SIRT2/SPRY2/CHI3L1/TRIM6/PARD3/SMAD7/TGFB1/PPEF2/EGF/PLK1/PRKAG2/WNT5A/TNKS1BP1	13
BP	GO:2000107	negative regulation of leukocyte apoptotic process	13/2486	47/18670	0.006943	0.05664	0.0444	ARG2/FADD/BCL10/GAS6/CXCL12/MIR17HG/IRS2/IL2/CCL21/HCLS1/TSC22D3/DOCK8/AXL	13
BP	GO:0033280	response to vitamin D	11/2486	37/18670	0.007058	0.05716	0.0448	TGFB1/KANK2/ALPL/SPP1/PHEX/TRIM24/STC1/PTN/SFRP1/STC2/TNC	11
BP	GO:0043114	regulation of vascular permeability	11/2486	37/18670	0.007058	0.05716	0.0448	DDAH1/TGFB1/PTP4A3/PDE2A/BDKRB2/RAMP2/CEACAM1/HRH1/TEK/CDH5/SLIT2	11
BP	GO:0060323	head morphogenesis	11/2486	37/18670	0.007058	0.05716	0.0448	CLDN5/EP300/NIPBL/TGFB1/TIPARP/ASPH/PDGFRA/CSRNP1/MSX1/TBX1/SSBP3	11
BP	GO:1905314	semi-lunar valve development	11/2486	37/18670	0.007058	0.05716	0.0448	HEYL/TWIST1/TGFB2/TGFB1/GJA5/ELN/NOS3/SOX9/NOTCH1/NOTCH2/SLIT2	11
BP	GO:0015931	nucleobase-containing compound transport	46/2486	241/18670	0.007071	0.05716	0.0448	SRRM1/NXF3/EIF5A/TOMM20/SLC25A33/NXT1/AKAP8L/SLC35A3/SLC25A5/YTHDC1/SARNP/SFPQ/NUP93/DHX9/RPS15/THOC2/ZFP36/U2AF1L4/DDX19A/NUP50/G3BP2/P2RX7/SLBP/SLC25A6/NUP153/U2AF1/NUP210/PABPN1/RAE1/NUP188/NUP160/SLC28A3/NUP54/NXF1/NUP214/NUP155/MYO1C/MRPL18/MCM3AP/KHDRBS1/SMG6/ARC/RFTN2/POLR2D/ABCE1/SETD2	46
BP	GO:0030517	negative regulation of axon extension	12/2486	42/18670	0.007071	0.05716	0.0448	SEMA3B/RNF6/PLXNA3/SEMA3G/NRP1/SEMA4D/SEMA6D/SEMA5B/MAP2/CDK5R1/WNT5A/SEMA3E	12
BP	GO:0097028	dendritic cell differentiation	12/2486	42/18670	0.007071	0.05716	0.0448	GATA1/TGFB1/GAS6/FCGR2B/BATF2/IRF4/TRAF6/BATF/TREM2/LYN/BATF3/AXL	12
BP	GO:0050684	regulation of mRNA processing	29/2486	137/18670	0.00711	0.05741	0.04499	TRA2B/RBM4/CPSF7/MBNL1/WTAP/YTHDC1/PAPOLA/DHX9/SAFB2/CDK9/RBM7/SRPK2/SF3B4/RBM3/ZBTB7A/RBMXL1/PABPN1/JMJD6/TRA2A/HNRNPK/CELF1/ZC3H10/CPEB1/KHDRBS1/KHDRBS3/REST/RBMX/MBNL2/BARD1	29
BP	GO:1901861	regulation of muscle tissue development	32/2486	155/18670	0.007162	0.05764	0.04518	SIRT2/YY1/MAPK11/TBX5/TWIST1/AKIRIN1/TGFB1/CREB1/CYP26B1/FLCN/BMP2/LOX/IGF1/SIX1/MIR17HG/IGFBP5/NR1D2/EFNB2/CDON/FRS2/MTM1/TBX2/NOTCH1/SHOX2/YAP1/JARID2/GPC1/ZFPM2/TBX1/MTOR/SOX6/PIN1	32
BP	GO:1903707	negative regulation of hemopoiesis	32/2486	155/18670	0.007162	0.05764	0.04518	KLF13/C1QC/INPP5D/INHBA/NFKBIA/PGLYRP1/IRF1/SMAD7/HOXA7/LTF/TAL1/LDB1/PRDX2/ZFP36/HES1/FBXW7/FCGR2B/MIR21/ZC3H12A/HLX/MEIS2/CEACAM1/IL2/NOTCH1/GLI3/IL17D/SFRP1/LYN/HOXA9/FBN1/RC3H1/HSPA9	32
BP	GO:2001057	reactive nitrogen species metabolic process	20/2486	85/18670	0.007184	0.05764	0.04518	CLU/HBB/DDAH1/MMP8/ARG2/TNF/HSP90AA1/ZC3H12A/GCH1/NOS3/ASS1/KLF4/CD34/ACP5/IL1B/CPS1/HSP90AB1/CAV1/MTOR/NQO1	20
BP	GO:0016570	histone modification	79/2486	454/18670	0.007193	0.05764	0.04518	MUC1/SIRT2/RBM14/PHF20/UTY/NCOA3/RLF/POLE3/MSL2/EP300/BCOR/AKAP8L/NIPBL/PRDM6/PRKCB/SNCA/KDM5D/TAF10/TWIST1/SFPQ/HAT1/YEATS2/TGFB1/PINK1/CDK9/LDB1/ING3/KDM6B/ARID4A/BRMS1L/WDR5/FLCN/CREBBP/HSF4/KDM2A/IRF4/TRRAP/GTF3C4/USP7/SIRT1/SETD5/MTA1/WAC/JMJD6/RSF1/SETD1B/NSD1/MORF4L2/HCFC1/MCM3AP/JMJD1C/DTX3L/PRDM5/JARID2/IL1B/WDR70/REST/EP400/SUDS3/PPM1F/SIRT7/CHD5/AKAP8/PCGF2/CTCFL/EZH1/SIN3B/SET/TAF1/RPS6KA5/EPC1/PER1/NR1H4/SETD2/SIN3A/MTHFR/RNF8/NCOA1/ING5	79
BP	GO:0031571	mitotic G1 DNA damage checkpoint	16/2486	63/18670	0.007194	0.05764	0.04518	MUC1/CRADD/CNOT8/CNOT4/EP300/RPS27L/CCND1/MDM4/PML/PLK3/BTG2/CNOT7/TRIAP1/TNKS1BP1/E2F8/CNOT1	16
BP	GO:0044819	mitotic G1/S transition checkpoint	16/2486	63/18670	0.007194	0.05764	0.04518	MUC1/CRADD/CNOT8/CNOT4/EP300/RPS27L/CCND1/MDM4/PML/PLK3/BTG2/CNOT7/TRIAP1/TNKS1BP1/E2F8/CNOT1	16
BP	GO:0046777	protein autophosphorylation	45/2486	235/18670	0.007217	0.05774	0.04526	MKNK2/BMX/PDPK1/EIF2AK4/CLK1/FLT1/JUN/VEGFC/PINK1/ACE/EIF2S1/ERN1/STK24/IGF1R/BTK/PPP2R5E/EGFR/TRIM24/NTRK2/ULK2/DAPK2/EPHB4/PDGFRA/STK10/STK4/MELK/CLK3/PDGFRB/TEK/THY1/GPNMB/DDR2/CAV1/MAP3K3/MAPKAPK5/TTK/MTOR/LYN/KDR/TNKS1BP1/TAF1/UHMK1/PTPRC/NEK2/RASSF2	45
BP	GO:0051047	positive regulation of secretion	75/2486	428/18670	0.007307	0.05819	0.04561	SRI/ORM1/SYTL4/MMP8/EDNRB/CD177/MBP/INHBA/ARF1/MAPK11/TRIM6/SNCA/TNF/TWIST1/LPL/GHRL/TGFB2/SCT/FRMD4A/VEGFC/DHX9/CD244/TGFB1/PINK1/CYP4F2/SERP1/TRH/PFKFB2/CREB1/C2CD2L/CLASP2/STXBP1/PPID/SMPD3/PTGER4/EDN3/SPP1/TM7SF3/EGFR/IFIH1/P2RX7/IGF1/CXCL12/CADPS2/TNFRSF11A/IRS2/P2RY2/C1QTNF1/IL2/AQP1/TNFRSF14/CD34/IL1B/STX4/IL33/TREM2/PPP3CB/PSMD9/FZD5/NLRP1/OXTR/WNT5A/IL26/PARD6A/CAPN10/CLASP1/POSTN/ADCYAP1/FRMD8/MYH10/UNC13B/NR1H4/SLC6A1/ABAT/NLRP7	75
BP	GO:0051145	smooth muscle cell differentiation	18/2486	74/18670	0.00731	0.05819	0.04561	ACVR1/EDNRB/PRDM6/TGFB1/HES1/RBPMS2/MIR21/NFATC4/SIRT1/NPNT/SIX1/RAMP2/SOX9/NOTCH1/SGCB/EPC1/NFATC3/OLFM2	18
BP	GO:0070373	negative regulation of ERK1 and ERK2 cascade	18/2486	74/18670	0.00731	0.05819	0.04561	SPRY2/SLC9A3R1/DLG1/DUSP10/SPRY1/TNIP1/MIR21/FLCN/SPRY4/TIMP3/KLF4/FBLN1/DUSP1/LYN/RGS14/EPHB2/PTPRC/PIN1	18
BP	GO:0072078	nephron tubule morphogenesis	18/2486	74/18670	0.00731	0.05819	0.04561	IRX2/PBX1/DLG1/TGFB1/HES1/BMP2/IRX3/NPNT/SIX1/HOXB7/SMO/SOX9/GLI3/HOXA11/ADAMTS16/SIX2/GZF1/LZTS2	18
BP	GO:0043542	endothelial cell migration	51/2486	273/18670	0.007321	0.05821	0.04562	ITGB3/ANXA3/PDPK1/PPARG/SPARC/RAB13/VEGFC/TGFB1/PTP4A3/NRP1/FBXW7/MIR21/ZC3H12A/FGF18/MMRN2/SIRT1/JUP/NOS3/HSPB1/STC1/SMOC2/ADAMTS9/PLEKHG5/CARD10/VASH1/PTN/EPHB4/RHOJ/CEACAM1/NR2F2/DNAJA4/SRPX2/EFNB2/MEOX2/BCAR1/KLF4/EMP2/NOTCH1/CLEC14A/MYH9/TEK/FAP/ANGPT2/PDCD10/WNT5A/DCN/MAP3K3/SLIT2/KDR/GIPC1/CCBE1	51
BP	GO:0032526	response to retinoic acid	24/2486	108/18670	0.007365	0.05841	0.04578	PPARG/WNT5B/IGFBP2/PHB2/RXRB/CREB1/CYP26B1/WNT9A/FZD10/GDAP2/AQP1/KLF4/PDGFRB/SOX9/TIE1/YAP1/ALDH1A2/WNT5A/DUSP1/TBX1/LYN/FZD4/TNC/NCOA1	24
BP	GO:0071156	regulation of cell cycle arrest	24/2486	108/18670	0.007365	0.05841	0.04578	MUC1/CRADD/CNOT8/CNOT4/EP300/SLC25A33/TGFB1/CDK9/CCND1/MDM4/PML/PLK3/POU4F1/BTG2/FAP/CRLF3/CDK5R1/CNOT7/HSP90AB1/TRIAP1/TNKS1BP1/E2F8/ZNF268/CNOT1	24
BP	GO:0043543	protein acylation	47/2486	248/18670	0.007468	0.05907	0.0463	MUC1/PHF20/NCOA3/POLE3/MSL2/EP300/CLIP3/SNCA/TAF10/TWIST1/HAT1/NAA16/YEATS2/TGFB1/LDB1/ING3/NAA30/WDR5/FLCN/CREBBP/IRF4/TRRAP/GTF3C4/RAPGEF3/SIRT1/SETD5/NAT9/RSF1/PPM1A/MORF4L2/HCFC1/NUPR1/MCM3AP/IL1B/NAA25/EP400/CHD5/PCGF2/SET/TAF1/RPS6KA5/EPC1/PER1/SIN3A/NAA15/NCOA1/ING5	47
BP	GO:0060055	angiogenesis involved in wound healing	8/2486	23/18670	0.007478	0.05907	0.0463	ITGB3/TNFAIP3/CX3CL1/GPR4/SMOC2/ADIPOR2/CD34/MCAM	8
BP	GO:0007565	female pregnancy	38/2486	192/18670	0.007487	0.05907	0.0463	ARID1A/FOSB/ARG1/HPGD/ADCY7/GHRL/TGFB1/STOX2/IGFBP2/FKBP4/MIR21/PAM/COL16A1/FOS/SPP1/SP3/HSD11B2/STC1/RPL29/ADIPOR2/ITGA3/PTN/RAMP2/MMP9/NR2F2/IGFBP5/EMP2/IL1B/ANGPT2/OXTR/FBLN1/BYSL/STC2/MTOR/ADCYAP1/ITGA2/KLF1/JUNB	38
BP	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	38/2486	192/18670	0.007487	0.05907	0.0463	ITGB3/ACVR1/NTF3/GATA1/BDNF/TNF/GHRL/UNC119/TGFB1/TAL1/HES1/NRP1/GAS6/CRLF1/ACE/FBXW7/ADRA2A/PARP9/THBS4/NTRK2/IL23R/SEMA4D/IGF1/EGF/IL12A/IL2/AFAP1L2/TNFRSF14/NEDD9/TREM2/ENPP2/NOX4/HCLS1/CSPG4/MTOR/LYN/GHR/PTPRC	38
BP	GO:0045446	endothelial cell differentiation	25/2486	114/18670	0.007535	0.05932	0.04649	ACVR1/HOXB5/CLDN5/MYADM/PROC/TNF/KDM6B/PDE2A/NRP1/MIR21/RAPGEF3/COL18A1/STC1/PDPN/MSN/PTN/CEACAM1/NR2F2/NOTCH1/IL1B/APOLD1/TJP1/CDH5/KDR/FOXJ2	25
BP	GO:0014909	smooth muscle cell migration	21/2486	91/18670	0.007537	0.05932	0.04649	ITGB3/SSH1/TPM1/SORL1/NRP1/ACE/MIR21/IGF1/SEMA6D/IGFBP5/PLAT/PDGFRB/HAS2/PLXNA1/NOX4/MIR214/SLIT2/POSTN/ITGA2/PARVA/IGFBP3	21
BP	GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors	15/2486	58/18670	0.007631	0.05998	0.04701	PMAIP1/FAIM2/TNFAIP3/FADD/RAF1/ITPRIP/BCL2L1/NOS3/SFRP2/SKIL/STK4/TIMP3/STX4/SFRP1/MADD	15
BP	GO:0008406	gonad development	42/2486	217/18670	0.007642	0.05999	0.04702	MAMLD1/INHBA/GATA1/RAB13/TAF4/TGFB2/CRKL/SAFB2/ARID4A/TIPARP/CCND1/FOXC1/WDR19/SIRT1/BCL2L1/NOS3/SFRP2/ACVR2A/PDGFRA/CBL/HOXA10/MMP19/PDGFRB/NUPR1/SOX9/HOXA11/SFRP1/RXFP2/ZFPM2/NUP210L/WNT5A/FLNA/HMGCS1/SLIT2/HOXA9/ADCYAP1/FZD4/HSPA5/EIF2B2/LHX8/ZNF830/NCOA1	42
BP	GO:0046879	hormone secretion	57/2486	312/18670	0.007695	0.06033	0.04728	SRI/LRP5L/SYTL4/CAMK2G/ITPR1/CDK16/INHBA/SLC25A5/CACNA2D2/SNX19/TNF/GHRL/SCT/SERP1/TRH/RAB11FIP1/PFKFB2/RAB11FIP5/CREB1/C2CD2L/ICA1/ADRA2A/SMPD3/RAF1/RAPGEF3/BTK/EDN3/SPP1/JAGN1/TM7SF3/EGFR/CPE/SLC25A6/IRS2/KCNA5/AGTR1/C1QTNF1/BMP8A/SNAP23/IL1B/STX4/FKBP1B/SFRP1/PPP3CB/PSMD9/REST/CAPN10/LYN/ADCYAP1/KCNS3/FZD4/MIDN/LTBP4/NR1H4/LRP5/RAPGEF4/ABAT	57
BP	GO:0045667	regulation of osteoblast differentiation	27/2486	126/18670	0.007769	0.06083	0.04768	ACVR1/JUND/TMEM119/TNF/TWIST1/LTF/TWSG1/MIR21/SMAD1/BMP2/FBN2/TWIST2/SFRP2/SEMA4D/NPNT/ACVR2A/IGF1/IGFBP5/SMOC1/NOTCH1/GLI3/CTHRC1/SFRP1/REST/DDR2/LRP5/RASSF2	27
BP	GO:0051146	striated muscle cell differentiation	54/2486	293/18670	0.007801	0.06101	0.04782	ARID1A/ACVR1/TMOD1/YY1/BDNF/TBX5/CACNA2D2/CD9/CAV2/TMEM119/BHLHE41/TGFB1/TPM1/PTGFRN/KDM6B/AKAP13/CYP26B1/BMP2/SGCD/EHD2/LOX/UCHL1/OBSL1/LDB3/IGF1/SIX1/PDGFRA/IGFBP5/LMOD1/ALPK3/EFNB2/CDON/SMO/FRS2/PDGFRB/MORF4L2/KLF5/NOTCH1/SHOX2/MYH9/FLNC/CSRP2/NOX4/SGCB/MSX1/ALPK2/TBX1/FER1L5/MTOR/MYH10/DMD/CSRP1/SOX6/PIN1	54
BP	GO:0022407	regulation of cell-cell adhesion	71/2486	403/18670	0.007823	0.06108	0.04788	FAM49B/SH2B3/PDPK1/HLA-DPB1/ARG2/MBP/FADD/ITGA4/MYADM/ARG1/CD9/IRF1/TNF/SMAD7/DLG1/YTHDF2/DUSP10/BCL10/TGFB1/IGFBP2/ELANE/PRDX2/CD276/HES1/FCGR2B/CX3CL1/CD83/TWSG1/MIR21/ZC3H12A/BMP2/NFKBIZ/HLX/TRAF6/IL23R/CYLD/VAV1/CEACAM6/IGF1/RELA/CXCL12/PDPN/ASS1/CEACAM1/PDCD1LG2/IL12A/EFNB2/C1QTNF1/IL2/KLF4/HAS2/TNFRSF14/GLI3/IL1B/CCL21/THY1/GPNMB/PPM1F/WNT5A/PAK3/PODXL/CD300A/CAV1/LYN/SPN/SPINT2/RC3H1/PTPRC/CORO1A/DOCK8/ABAT	71
BP	GO:0030316	osteoclast differentiation	22/2486	97/18670	0.007835	0.06108	0.04788	INPP5D/CSF1/TNF/CD109/LTF/IREB2/TGFB1/CREB1/FBXW7/FOS/TRAF6/IL23R/TNFRSF11A/KLF10/POU4F1/NOTCH2/SFRP1/TREM2/MTOR/FBN1/JUNB/RASSF2	22
BP	GO:0030518	intracellular steroid hormone receptor signaling pathway	28/2486	132/18670	0.00784	0.06108	0.04788	RBM14/ARID1A/GRIP1/NCOA3/FHL2/EP300/HEYL/RNF6/KDM5D/DNAJA1/SAFB2/FKBP4/PHB2/KANK2/ZBTB7A/DAB2/SIRT1/DDX54/TGFB1I1/YAP1/SFRP1/SKP2/NR3C1/TAF1/PER1/NCOA6/CNOT1/NCOA1	28
BP	GO:0071300	cellular response to retinoic acid	17/2486	69/18670	0.007866	0.06116	0.04794	PPARG/WNT5B/PHB2/CREB1/CYP26B1/WNT9A/FZD10/AQP1/KLF4/SOX9/YAP1/ALDH1A2/WNT5A/TBX1/LYN/FZD4/TNC	17
BP	GO:0006402	mRNA catabolic process	65/2486	364/18670	0.00787	0.06116	0.04794	RPS27/PSMD14/PSMD12/RPS28/LSM4/PABPC4/PELO/PNRC2/CNOT8/CNOT4/YTHDF2/PPP2CA/FXR1/DHX9/PSMD7/HNRNPM/PSMB5/RPS15/LSM7/TNRC6B/ZFP36/UBA52/ERN1/RPS26/LARP1/RPLP1/RPL28/RPS3A/DCP2/ZC3H12A/MTPAP/RPL10/EXOSC3/HSPB1/RPL29/POLR2G/YWHAZ/RPS8/RPS4Y1/RPS2/RPL39/RPS10/NUP214/PSMB7/YBX1/RPL6/PSMD1/BTG2/PSMD9/UBC/SMG6/YTHDF3/CNOT7/RPL14/RPS7/MTOR/SET/TNKS1BP1/PSME1/POLR2D/RC3H1/RPL9/RPL15/DDX6/CNOT1	65
BP	GO:0016331	morphogenesis of embryonic epithelium	31/2486	150/18670	0.007907	0.06137	0.0481	ARID1A/IRX2/TWIST1/BCL10/TGFB2/VEGFC/TGFB1/PHACTR4/JAG2/LUZP1/IRX3/TRAF6/SFRP2/LIAS/SIX1/STK4/TGFB1I1/SULF1/SEC24B/SOX9/ALDH1A3/CTHRC1/SFRP1/ALDH1A2/WNT5A/RPS7/DLC1/PFN1/SPINT2/SETD2/MTHFR	31
BP	GO:0009743	response to carbohydrate	44/2486	230/18670	0.007958	0.0617	0.04835	SRI/LRP5L/TRA2B/SLC2A5/ME1/SPARC/CDK16/PRKCB/LPL/GHRL/TGFB1/TRH/PFKFB2/RAB11FIP5/C2CD2L/GAS6/ERN1/ADRA2A/RAF1/IGF1R/SESN2/JAGN1/CALCRL/GJB6/IRS2/SLC26A6/KHK/POLG/IL1B/STX4/FKBP1B/ANGPT2/PPP3CB/NOX4/COLEC12/COL6A2/LYN/ITGA2/UNC13B/NR1H4/SLC6A1/LRP5/SIN3A/EIF2B2	44
BP	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	20/2486	86/18670	0.008218	0.06355	0.04981	PMAIP1/CRADD/FAIM2/TNFAIP3/FADD/TNF/DEDD2/MOAP1/RAF1/ITPRIP/BCL2L1/NOS3/SFRP2/SKIL/STK4/TIMP3/DIABLO/STX4/SFRP1/MADD	20
BP	GO:0070542	response to fatty acid	20/2486	86/18670	0.008218	0.06355	0.04981	PPARG/YY1/LPL/CREB1/ZC3H12A/NFATC4/PTGER4/ADCY6/ASS1/PTGFR/AKR1C2/CPS1/CCL21/SFRP1/AKAP8/PDK4/TNC/NR1H4/FABP3/HMGCL	20
BP	GO:1904994	regulation of leukocyte adhesion to vascular endothelial cell	9/2486	28/18670	0.008284	0.06398	0.05015	ITGA4/TNF/ELANE/MIR21/TRAF6/RELA/CXCL12/KLF4/CCL21	9
BP	GO:0022408	negative regulation of cell-cell adhesion	36/2486	181/18670	0.008373	0.06451	0.05056	SH2B3/ARG2/MBP/MYADM/ARG1/CD9/IRF1/SMAD7/DLG1/YTHDF2/TGFB1/PRDX2/FCGR2B/TWSG1/MIR21/ZC3H12A/BMP2/HLX/CXCL12/ASS1/CEACAM1/PDCD1LG2/C1QTNF1/IL2/KLF4/TNFRSF14/GLI3/CCL21/GPNMB/PPM1F/PODXL/CD300A/SPN/SPINT2/RC3H1/ABAT	36
BP	GO:0048015	phosphatidylinositol-mediated signaling	36/2486	181/18670	0.008373	0.06451	0.05056	SIRT2/NTF3/SLC9A3R1/PEAR1/PTPN13/TNF/TWIST1/FLT1/TGFB2/SELP/MIR21/IER3/IGF1R/GPR143/SIRT1/EGFR/NTRK2/SEMA4D/IGF1/PLCB2/PLCB1/PDGFRA/CBL/CEACAM1/IRS2/PIK3CD/KLF4/PDGFRB/HCST/SOX9/TEK/DCN/HCLS1/INPP5F/LYN/KDR	36
BP	GO:0045600	positive regulation of fat cell differentiation	16/2486	64/18670	0.008434	0.06482	0.0508	PPARG/LPL/WNT5B/CREB1/ZFP36/MIR21/ZC3H12A/BMP2/RARRES2/SFRP2/CCDC3/STK4/KLF5/WDFY2/SFRP1/LRP5	16
BP	GO:0045669	positive regulation of osteoblast differentiation	16/2486	64/18670	0.008434	0.06482	0.0508	ACVR1/JUND/TMEM119/LTF/MIR21/SMAD1/BMP2/FBN2/SFRP2/NPNT/ACVR2A/IGF1/GLI3/CTHRC1/DDR2/LRP5	16
BP	GO:0001960	negative regulation of cytokine-mediated signaling pathway	18/2486	75/18670	0.008449	0.06486	0.05083	SH2B3/OTUD4/PPARG/ARG1/YTHDF2/NOL3/PXDN/SAMHD1/GAS6/MIR21/ECM1/CCDC3/YTHDF3/CNOT7/CAV1/SLIT2/PTPRC/NR1H4	18
BP	GO:0002695	negative regulation of leukocyte activation	35/2486	175/18670	0.008467	0.06491	0.05088	INPP5D/TNFAIP3/ARG2/PARP3/ARG1/INHBA/PGLYRP1/IRF1/SMAD7/DLG1/TGFB1/PRDX2/RHBDD3/FCGR2B/CX3CL1/TWSG1/MIR21/ZC3H12A/HLX/BTK/CEACAM1/IL13RA2/PDCD1LG2/IL2/TNFRSF14/GLI3/CD300LF/SFRP1/GPNMB/CD300A/LYN/SPN/RC3H1/PTPRC/AXL	35
BP	GO:0048660	regulation of smooth muscle cell proliferation	34/2486	169/18670	0.00855	0.06546	0.0513	TNFAIP3/XRCC6/PPARG/MEF2D/HPGD/TNF/JUN/TPM1/ELANE/RBPMS2/ERN1/CX3CL1/MIR21/SMPD3/ELN/TRAF6/CALCRL/EGFR/MAP3K5/IGF1/MMP9/IGFBP5/IL12A/KLF4/PDGFRB/PDE1A/SKP2/MIR214/OGN/MTOR/ITGA2/NOTCH3/FOXJ2/IGFBP3	34
BP	GO:0010544	negative regulation of platelet activation	7/2486	19/18670	0.008591	0.06546	0.0513	SH2B3/CD9/NOS3/PDGFRA/CEACAM1/C1QTNF1/ABAT	7
BP	GO:0016973	poly(A)+ mRNA export from nucleus	7/2486	19/18670	0.008591	0.06546	0.0513	NXF3/NUP93/THOC2/DDX19A/PABPN1/NXF1/MCM3AP	7
BP	GO:0036303	lymph vessel morphogenesis	7/2486	19/18670	0.008591	0.06546	0.0513	VEGFC/FOXC1/PDPN/VASH1/PPP3CB/PTPN14/CCBE1	7
BP	GO:0048486	parasympathetic nervous system development	7/2486	19/18670	0.008591	0.06546	0.0513	NAV2/PLXNA3/HES1/NRP1/ADARB1/SIX1/TBX1	7
BP	GO:0045727	positive regulation of translation	27/2486	127/18670	0.008646	0.0656	0.05142	PPP1R15A/EIF5A/RPS27L/EIF2AK4/TNF/YTHDF2/FXR1/DHX9/PINK1/SERP1/RBM3/LARP1/YTHDF1/POLR2G/PRR16/KHDRBS1/MIF4GD/YTHDF3/RMND1/PCIF1/RBMS3/MTOR/ITGA2/CDC123/UHMK1/POLR2D/LARP6	27
BP	GO:0030072	peptide hormone secretion	47/2486	250/18670	0.008663	0.0656	0.05142	SRI/LRP5L/SYTL4/CAMK2G/ITPR1/CDK16/SLC25A5/CACNA2D2/SNX19/TNF/GHRL/SCT/SERP1/TRH/PFKFB2/RAB11FIP5/C2CD2L/ICA1/ADRA2A/SMPD3/RAF1/RAPGEF3/EDN3/JAGN1/TM7SF3/EGFR/CPE/SLC25A6/IRS2/KCNA5/BMP8A/IL1B/STX4/FKBP1B/SFRP1/PPP3CB/PSMD9/REST/CAPN10/ADCYAP1/KCNS3/MIDN/LTBP4/NR1H4/LRP5/RAPGEF4/ABAT	47
BP	GO:0006891	intra-Golgi vesicle-mediated transport	10/2486	33/18670	0.008673	0.0656	0.05142	COG3/GOLGA5/GABARAPL2/TRAPPC10/COPB2/GOSR1/RAB6B/GOLGA3/COPZ2/NAPG	10
BP	GO:0035115	embryonic forelimb morphogenesis	10/2486	33/18670	0.008673	0.0656	0.05142	NIPBL/TBX5/TWIST1/WNT9A/SHOX2/HOXA11/ALDH1A2/MSX1/HOXA9/HOXD9	10
BP	GO:0061036	positive regulation of cartilage development	10/2486	33/18670	0.008673	0.0656	0.05142	SMAD1/FGF18/BMP2/RELA/SOX9/GLI3/HOXA11/WNT5A/PKDCC/SOX6	10
BP	GO:1901890	positive regulation of cell junction assembly	10/2486	33/18670	0.008673	0.0656	0.05142	NRP1/COL16A1/NPHP1/TEK/SFRP1/THY1/LIMS1/PPM1F/CAV1/KDR	10
BP	GO:0048009	insulin-like growth factor receptor signaling pathway	11/2486	38/18670	0.008763	0.0662	0.05189	IGFBP2/GIGYF1/IGF1R/BMP2/IGF1/PLCB1/IGFBP4/IGFBP5/CILP/GHR/IGFBP3	11
BP	GO:0031341	regulation of cell killing	22/2486	98/18670	0.008864	0.06688	0.05242	FAM49B/CD1C/CR1L/CFH/FADD/ARG1/PGLYRP1/CD59/FCGR2B/CD1B/IL23R/VAV1/P2RX7/CXCL6/HLA-B/CEACAM1/IL12A/SERPINB9/PPP3CB/HSP90AB1/PTPRC/HLA-A	22
BP	GO:0060761	negative regulation of response to cytokine stimulus	19/2486	81/18670	0.008948	0.06744	0.05285	SH2B3/OTUD4/PPARG/ARG1/YTHDF2/NOL3/PXDN/SAMHD1/GAS6/MIR21/ECM1/CCDC3/KLF4/YTHDF3/CNOT7/CAV1/SLIT2/PTPRC/NR1H4	19
BP	GO:0033619	membrane protein proteolysis	15/2486	59/18670	0.009001	0.06748	0.05289	MBTPS1/TNF/SPPL3/TGFB1/ADRA2A/TRAF6/P2RX7/RELA/TIMP3/LRIG2/MYH9/IL1B/TIMP4/RBMX/SH3D19	15
BP	GO:0072413	signal transduction involved in mitotic cell cycle checkpoint	15/2486	59/18670	0.009001	0.06748	0.05289	MUC1/CRADD/CNOT8/CNOT4/EP300/MIR21/MDM4/PML/PLK3/BTG2/CNOT7/TRIAP1/TNKS1BP1/E2F8/CNOT1	15
BP	GO:1902402	signal transduction involved in mitotic DNA damage checkpoint	15/2486	59/18670	0.009001	0.06748	0.05289	MUC1/CRADD/CNOT8/CNOT4/EP300/MIR21/MDM4/PML/PLK3/BTG2/CNOT7/TRIAP1/TNKS1BP1/E2F8/CNOT1	15
BP	GO:1902403	signal transduction involved in mitotic DNA integrity checkpoint	15/2486	59/18670	0.009001	0.06748	0.05289	MUC1/CRADD/CNOT8/CNOT4/EP300/MIR21/MDM4/PML/PLK3/BTG2/CNOT7/TRIAP1/TNKS1BP1/E2F8/CNOT1	15
BP	GO:0006367	transcription initiation from RNA polymerase II promoter	37/2486	188/18670	0.009008	0.06748	0.05289	MED10/PPARG/GTF2I/TBX5/TAF4/TAF10/CDK9/MED8/RXRB/PPM1D/CREB1/GTF2H3/MED7/CCND1/CREBBP/THRB/MED13/WWTR1/MED6/POLR2G/TAF3/NR1D2/MED30/TEAD4/SOX9/NOTCH1/NOTCH2/YAP1/NR2F6/GTF2E1/NR3C1/NR4A2/TAF1/POLR2D/NOTCH3/NR1H4/NR5A2	37
BP	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	23/2486	104/18670	0.009102	0.0681	0.05337	CTTN/ACVR1/FAIM2/TNFAIP3/FADD/GATA1/TNF/NOL3/STRADB/PRDX2/NRP1/CX3CL1/RAF1/ITPRIP/BCL2L1/NOS3/SFRP2/IGF1/RELA/MCL1/IFI6/YAP1/IL1B	23
BP	GO:0008217	regulation of blood pressure	36/2486	182/18670	0.009134	0.06826	0.0535	HBB/SUCNR1/SLC2A5/DDAH1/MME/EDNRB/PTPRO/CTSG/PPARG/NAV2/VEGFC/TPM1/CYP4F2/GAS6/ACE/GJA5/GRIP2/EDN3/GCH1/HSD11B2/NOS3/GNB3/RAMP2/NR2F2/AGTR1/EMP2/CD34/KCNK6/OXTR/ADAMTS16/POSTN/ACTA2/ENPEP/LRP5/ABAT/COL1A2	36
BP	GO:0006986	response to unfolded protein	35/2486	176/18670	0.009251	0.06896	0.05405	PPP1R15A/PPP1R15B/MBTPS1/EDEM1/EP300/HSP90B1/DNAJA1/SERP1/HYOU1/HERPUD1/EIF2S1/CCND1/ERN1/HSP90AA1/SSR1/DDX11/THBS4/DDIT3/TM7SF3/HSPB1/DERL1/SERPINH1/TBL2/VCP/CREB3L1/STT3B/KDELR3/HSP90AB1/STC2/BAK1/HSPB3/WFS1/HSPA5/HSPB8/HSPA9	35
BP	GO:0051897	positive regulation of protein kinase B signaling	35/2486	176/18670	0.009251	0.06896	0.05405	SPRY2/CHI3L1/NRG4/BAG4/TNF/TGFB1/PINK1/GAS6/CX3CL1/HSP90AA1/MIR21/P2RY12/IGF1R/FGF18/EGFR/VAV1/EGF/PDGFRA/AKR1C2/IRS2/IGFBP5/PIK3CD/C1QTNF1/RAMP3/FRS2/PDGFRB/TEK/CCL21/NOX4/IL26/HSP90AB1/HCLS1/MTOR/KL/AXL	35
BP	GO:0061387	regulation of extent of cell growth	24/2486	110/18670	0.00929	0.06917	0.05422	NRCAM/CTTN/FGF13/SEMA3B/BDNF/RNF6/PLXNA3/RND2/SEMA3G/NRP1/L1CAM/FN1/SPP1/SEMA4D/ULK2/CXCL12/SEMA6D/SEMA5B/MAP2/CDK5R1/WNT5A/SEMA3E/SIN3A/GDI1	24
BP	GO:0006022	aminoglycan metabolic process	34/2486	170/18670	0.009356	0.06958	0.05454	IDS/CHIT1/CHST1/B4GALT2/PGLYRP1/TGFB1/LYG2/AGRN/SMPD3/FOXC1/SDC2/GPC4/EGF/CHST3/GPC6/BGN/HS3ST2/PDGFRB/HAS2/IL1B/LYVE1/GPC1/HAS3/DCN/GALNT5/HAS1/ACAN/OGN/CSPG4/ITIH2/FMOD/PRELP/B4GALT4/HYAL1	34
BP	GO:0021987	cerebral cortex development	25/2486	116/18670	0.009433	0.06999	0.05486	TRA2B/FGF13/CCDC85C/LHX6/TACC1/CRKL/NRP1/P2RY12/EGFR/NTRK2/PLCB1/CDON/SMO/GLI3/LAMB1/CDK5R1/FLNA/NDE1/EMX2/GNG12/SLIT2/TACC2/SUN2/KIF14/NCOA1	25
BP	GO:0032988	ribonucleoprotein complex disassembly	6/2486	15/18670	0.009467	0.06999	0.05486	PELO/DENR/VCP/ZFAND1/KLC1/GFM2	6
BP	GO:0048569	post-embryonic animal organ development	6/2486	15/18670	0.009467	0.06999	0.05486	KLF4/MFAP2/FZD5/EFEMP1/BAK1/FBN1	6
BP	GO:0070571	negative regulation of neuron projection regeneration	6/2486	15/18670	0.009467	0.06999	0.05486	RGMA/RTN4RL1/SPP1/LRIG2/THY1/INPP5F	6
BP	GO:0072148	epithelial cell fate commitment	6/2486	15/18670	0.009467	0.06999	0.05486	ACVR1/NRP1/JAG2/PDPN/NR2F2/NOTCH1	6
BP	GO:0002703	regulation of leukocyte mediated immunity	39/2486	201/18670	0.009479	0.07	0.05486	FAM49B/CD1C/PDPK1/CD177/FADD/PARP3/ARG1/TNF/SMAD7/IL1R1/TGFB1/FBXO38/STXBP1/FCGR2B/CD1B/DDX21/BTK/EXOSC3/TRAF6/IL23R/VAV1/P2RX7/C12orf4/CXCL6/HLA-B/CEACAM1/IL13RA2/IL12A/IL2/SERPINB9/IL1B/STX4/PPP3CB/FZD5/CD300A/LYN/PTPRC/RSAD2/HLA-A	39
BP	GO:0140014	mitotic nuclear division	49/2486	264/18670	0.009522	0.07023	0.05504	SIRT2/EPS8/APC/AKAP8L/NIPBL/SMC5/CAV2/NCAPG/TGFB1/PHF13/MTBP/PHB2/ANLN/CDKN1C/CLASP2/CEP192/SMPD3/TPX2/CHMP6/CHMP1B/EDN3/KIF4A/UBE2S/CCDC8/HECW2/OBSL1/IGF1/MIS12/EGF/BUB1B/PLK1/PDGFRB/KIF2C/UBE2C/IL1B/FLNA/SIRT7/NDE1/DUSP1/AKAP8/TTK/CLASP1/PDS5A/CDK13/LRP5/KIF14/MKI67/NEK2/PIN1	49
BP	GO:0034101	erythrocyte homeostasis	26/2486	122/18670	0.009536	0.07025	0.05506	ALAS2/KLF13/SH2B3/EPB42/INPP5D/SLC4A1/INHBA/GATA1/L3MBTL3/TRIM58/IREB2/TAL1/LDB1/AHSP/ZFP36/ARID4A/ZBTB7A/SP3/ACVR2A/JMJD6/HCLS1/LYN/KLF1/SOX6/AXL/HSPA9	26
BP	GO:0043392	negative regulation of DNA binding	14/2486	54/18670	0.00955	0.07027	0.05508	SRI/GATA1/NFKBIA/JUN/IFI16/FBXW7/ZNF462/DDIT3/RSF1/SMO/MSX1/TAF1/SIN3A/NEK2	14
BP	GO:0001890	placenta development	31/2486	152/18670	0.009586	0.07034	0.05513	ARID1A/MME/PPARG/HTRA1/GHRL/ZFAT/STOX2/HES1/CDKN1C/SPP1/SP3/EGFR/STC1/VASH1/PTN/STK4/NR2F2/RSPO3/NDP/DLX3/FZD5/BPTF/ITGB8/DCN/HSP90AB1/STC2/E2F8/SPINT2/JUNB/SETD2/NCOA1	31
BP	GO:0098883	synapse pruning	5/2486	11/18670	0.009593	0.07034	0.05513	C1QB/C1QA/C1QC/CX3CL1/TREM2	5
BP	GO:1902946	protein localization to early endosome	5/2486	11/18670	0.009593	0.07034	0.05513	SORL1/NRP1/MSN/EGF/DTX3L	5
BP	GO:0006140	regulation of nucleotide metabolic process	30/2486	146/18670	0.009626	0.0705	0.05526	PDPR/ME1/SLC25A33/SNCA/NUP93/PINK1/PFKFB2/FLCN/ZBTB7A/NUP50/NOS3/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/VCP/RAE1/NUP188/COX7A1/NUP160/NUP54/PDP1/NUP214/NUP155/NUPR1/SLC2A6/PRKAG2/TREM2/PDK4	30
BP	GO:0032355	response to estradiol	28/2486	134/18670	0.009638	0.0705	0.05526	NCOA3/HPGD/TGFB1/IGFBP2/STXBP1/CCND1/PAM/EGFR/WFDC1/PTN/ASS1/PTGFR/RAMP2/TFPI/NR2F2/RAMP3/POU4F1/PDGFRB/SFRP1/ALDH1A2/OXTR/DUSP1/POSTN/ITGA2/CRYAB/SLC6A1/NQO1/NCOA1	28
BP	GO:0009914	hormone transport	58/2486	322/18670	0.009688	0.07074	0.05544	SRI/LRP5L/SYTL4/CAMK2G/ITPR1/CDK16/INHBA/SLC25A5/CACNA2D2/SNX19/TNF/GHRL/SCT/SERP1/TRH/RAB11FIP1/PFKFB2/RAB11FIP5/CREB1/C2CD2L/ICA1/ADRA2A/SMPD3/RAF1/RAPGEF3/BTK/EDN3/SPP1/JAGN1/TM7SF3/EGFR/SLCO4A1/CPE/SLC25A6/IRS2/KCNA5/AGTR1/C1QTNF1/BMP8A/SNAP23/IL1B/STX4/FKBP1B/SFRP1/PPP3CB/PSMD9/REST/CAPN10/LYN/ADCYAP1/KCNS3/FZD4/MIDN/LTBP4/NR1H4/LRP5/RAPGEF4/ABAT	58
BP	GO:0006476	protein deacetylation	21/2486	93/18670	0.009717	0.07074	0.05544	SIRT2/RBM14/BEX4/EP300/AKAP8L/NIPBL/SFPQ/TGFB1/PINK1/BRMS1L/SIRT1/MTA1/MORF4L2/PRDM5/REST/SUDS3/SIRT7/AKAP8/SIN3B/PER1/SIN3A	21
BP	GO:1901655	cellular response to ketone	21/2486	93/18670	0.009717	0.07074	0.05544	ADCY3/PPARG/ARG1/TGFB1/LARP1/PTGER4/SIRT1/SPP1/EGFR/ADCY6/MSN/ASS1/PTGFR/AKR1C2/AQP1/KLF4/SFRP1/NR3C1/AKAP8/CDC5L/TNC	21
BP	GO:0000380	alternative mRNA splicing, via spliceosome	18/2486	76/18670	0.009728	0.07074	0.05544	TRA2B/RBM4/MBNL1/WTAP/SFPQ/DHX9/HNRNPM/RBM7/RSRC1/ZBTB7A/PQBP1/CELF1/ZC3H10/KHDRBS1/REST/RBMX/MBNL2/CDK13	18
BP	GO:0072088	nephron epithelium morphogenesis	18/2486	76/18670	0.009728	0.07074	0.05544	IRX2/PBX1/DLG1/TGFB1/HES1/BMP2/IRX3/NPNT/SIX1/HOXB7/SMO/SOX9/GLI3/HOXA11/ADAMTS16/SIX2/GZF1/LZTS2	18
BP	GO:0042063	gliogenesis	53/2486	290/18670	0.009814	0.07129	0.05587	CLU/C1QA/SIRT2/PPARG/MPP5/WASF3/CSF1/PARD3/CD9/TNF/DUSP10/TGFB2/CRKL/TGFB1/TAL1/DAAM2/CREB1/HES1/CX3CL1/CDKN2C/P2RY12/BMP2/NFIB/EGFR/NTRK2/RELA/PTN/LGI4/MXRA8/TMEM98/SMO/GAP43/SOX9/NOTCH1/GLI3/IL1B/MATN2/IL33/TREM2/GPC1/LAMB1/CDK5R1/SH3TC2/NDN/ROR1/CSPG4/MTOR/LYN/OLIG1/ADCYAP1/SOX6/SUN2/EIF2B2	53
BP	GO:0032729	positive regulation of interferon-gamma production	16/2486	65/18670	0.009839	0.0713	0.05588	FAM49B/HLA-DPB1/FADD/IRF8/TNF/IL1R1/CD244/CD276/PDE4B/IL23R/IL12A/IL2/IL1B/FZD5/WNT5A/TLR9	16
BP	GO:0060675	ureteric bud morphogenesis	16/2486	65/18670	0.009839	0.0713	0.05588	PBX1/DLG1/TGFB1/HES1/BMP2/NPNT/SIX1/HOXB7/SMO/SOX9/GLI3/HOXA11/ADAMTS16/SIX2/GZF1/LZTS2	16
BP	GO:0001783	B cell apoptotic process	8/2486	24/18670	0.009931	0.07172	0.05621	BCL10/CRKL/BTK/MIR17HG/IRS2/IL2/LYN/BAK1	8
BP	GO:0003181	atrioventricular valve morphogenesis	8/2486	24/18670	0.009931	0.07172	0.05621	ACVR1/HEYL/TBX5/TWIST1/TGFB2/BMP2/MDM4/NOTCH1	8
BP	GO:1903010	regulation of bone development	8/2486	24/18670	0.009931	0.07172	0.05621	TMEM119/LTF/GHRL/FBXW7/LOX/NOTCH2/GLI3/FBN1	8
BP	GO:0002040	sprouting angiogenesis	36/2486	183/18670	0.009952	0.07179	0.05626	PDPK1/FLT1/GHRL/VEGFC/NRP1/FBXW7/SMAD1/RNF213/MMRN2/JAK1/ADAMTS9/CARD10/EPHB4/JMJD6/RAMP2/RHOJ/CEACAM1/SRPX2/AGTR1/EFNB2/RSPO3/MEOX2/KLF4/APLNR/CREB3L1/NOTCH1/CLEC14A/TEK/PDCD10/MAP3K3/SLIT2/KDR/E2F8/SEMA3E/PARVA/CCBE1	36
BP	GO:0001708	cell fate specification	22/2486	99/18670	0.01	0.07205	0.05647	APC/TBX5/NRP1/NANOG/SFRP2/DMRT3/HOXC10/SIX1/CDON/SMO/POU4F1/SOX9/TBX2/NOTCH1/GLI3/HOXA11/TBX15/FKBP8/TBX22/TBX1/SIX2/SOX6	22
BP	GO:0003044	regulation of systemic arterial blood pressure mediated by a chemical signal	13/2486	49/18670	0.01005	0.07236	0.05671	SUCNR1/SLC2A5/MME/CTSG/TPM1/ACE/GJA5/EDN3/HSD11B2/NOS3/AGTR1/OXTR/ENPEP	13
BP	GO:0050792	regulation of viral process	40/2486	208/18670	0.01008	0.07248	0.05681	IFI27/SLPI/STOM/EP300/TRIM6/EIF2AK4/CAV2/TNF/JUN/LTF/DHX9/IFITM3/CDK9/TRIM21/ZFP36/IFI16/TNIP1/ADARB1/SRPK2/PPID/LARP1/CHD1/ZC3H12A/ILF3/PML/POLR2G/VPS37B/RSF1/IFIT1/IFIT5/NOTCH1/IFITM2/PKN2/REST/CCL8/CNOT7/POLR2D/STAU1/RSAD2/NR5A2	40
BP	GO:0048659	smooth muscle cell proliferation	34/2486	171/18670	0.01022	0.07311	0.0573	TNFAIP3/XRCC6/PPARG/MEF2D/HPGD/TNF/JUN/TPM1/ELANE/RBPMS2/ERN1/CX3CL1/MIR21/SMPD3/ELN/TRAF6/CALCRL/EGFR/MAP3K5/IGF1/MMP9/IGFBP5/IL12A/KLF4/PDGFRB/PDE1A/SKP2/MIR214/OGN/MTOR/ITGA2/NOTCH3/FOXJ2/IGFBP3	34
BP	GO:0006614	SRP-dependent cotranslational protein targeting to membrane	23/2486	105/18670	0.01022	0.07311	0.0573	RPS27/RPS28/SEC61B/RPS15/UBA52/RPS26/RPLP1/RPL28/RPS3A/RPL10/RPL29/TRAM1L1/RPS8/RPS4Y1/RPS2/RPL39/RPS10/RPL6/RPL14/RPS7/SRP54/RPL9/RPL15	23
BP	GO:0034644	cellular response to UV	19/2486	82/18670	0.01023	0.07311	0.0573	C9orf116/MME/YY1/EP300/EIF2AK4/EIF2S1/PPID/CREBBP/USP28/NFATC4/SIRT1/PTN/BMF/AQP1/TRIAP1/BAK1/TAF1/MFAP4/HYAL1	19
BP	GO:0071158	positive regulation of cell cycle arrest	19/2486	82/18670	0.01023	0.07311	0.0573	MUC1/CRADD/CNOT8/CNOT4/EP300/TGFB1/MDM4/PML/PLK3/POU4F1/BTG2/FAP/CRLF3/CDK5R1/CNOT7/TRIAP1/TNKS1BP1/E2F8/CNOT1	19
BP	GO:0097581	lamellipodium organization	19/2486	82/18670	0.01023	0.07311	0.0573	ABLIM3/CTTN/PTPRO/WASF3/WASF2/AKIRIN1/P2RY12/ARHGEF7/PDPN/WHAMM/WASF1/ENPP2/NCKAP1/VAV3/RREB1/MIR214/ARPC2/SLIT2/MTOR	19
BP	GO:0098727	maintenance of cell number	32/2486	159/18670	0.01044	0.07455	0.05843	ARID1A/NCOA3/MED10/PELO/NIPBL/PBX1/TAL1/LDB1/ZC3H13/HES1/MED7/DPPA4/NANOG/RAF1/IGF1/POLR2G/PTN/KLF10/MED30/SMO/PRRX1/KLF4/SOX9/NOTCH1/NOTCH2/YAP1/SFRP1/REST/SIX2/POLR2D/DDX6/CNOT1	32
BP	GO:0003197	endocardial cushion development	12/2486	44/18670	0.01048	0.07456	0.05844	ACVR1/HEYL/TBX5/TWIST1/TGFB2/BMP2/MDM4/NOS3/SOX9/TBX2/NOTCH1/MSX1	12
BP	GO:0060412	ventricular septum morphogenesis	12/2486	44/18670	0.01048	0.07456	0.05844	ACVR1/HEYL/SMAD7/TGFB2/HES1/GJA5/NOS3/MIR17HG/NOTCH1/ZFPM2/WNT5A/SLIT2	12
BP	GO:0090257	regulation of muscle system process	48/2486	259/18670	0.01048	0.07456	0.05844	SRI/MYL9/CTTN/FGF13/CAMK2G/YY1/SMAD7/DLG1/NOL3/GHRL/CDK9/TPM1/TACR1/ADRA2A/GJA5/LMCD1/MIR21/ZC3H12A/PDE4B/GTF2IRD1/JUP/CALCRL/NOS3/STC1/NPNT/IGF1/UTRN/MIR17HG/IGFBP5/KCNMA1/KLF4/NOTCH1/JARID2/KCNA1/FKBP1B/HSPB6/ANK2/OXTR/MIR214/FLNA/RYR2/CAV1/MTOR/ITGA2/DMD/MTMR4/PIN1/ABAT	48
BP	GO:0051057	positive regulation of small GTPase mediated signal transduction	17/2486	71/18670	0.01055	0.075	0.05878	CSF1/CRKL/LPAR6/AKAP13/GPR4/VAV1/LPAR4/GPR35/IGF1/IRS2/CDON/PDGFRB/NOTCH1/NOTCH2/P2RY8/SOS2/LYN	17
BP	GO:0072538	T-helper 17 type immune response	9/2486	29/18670	0.01062	0.07512	0.05888	SMAD7/MIR21/ZC3H12A/IRF4/NFKBIZ/IL23R/BATF/IL2/RC3H1	9
BP	GO:0001738	morphogenesis of a polarized epithelium	29/2486	141/18670	0.01064	0.07512	0.05888	PSMD14/PSMD12/SLC9A3R1/PLEKHA4/PSMD7/PSMB5/GPC4/DAB2/AP2A2/SFRP2/MSN/GPC6/SEC24B/RSPO3/PSMB7/CTHRC1/PSMD1/SFRP1/PSMD9/FZD5/WNT5A/ROR1/MAGI2/PARD6A/INTU/FZD4/PSME1/PFN1/PRICKLE2	29
BP	GO:0009411	response to UV	29/2486	141/18670	0.01064	0.07512	0.05888	MSH6/C9orf116/MME/YY1/EP300/EIF2AK4/ELANE/ZRANB3/EIF2S1/CCND1/PPID/CREBBP/SCARA3/USP28/NFATC4/SIRT1/EGFR/PML/RELA/UBE4B/PTN/IL12A/BMF/AQP1/TRIAP1/BAK1/TAF1/MFAP4/HYAL1	29
BP	GO:0061097	regulation of protein tyrosine kinase activity	20/2486	88/18670	0.01065	0.07512	0.05888	SH3BP5L/BDNF/GHRL/UNC119/TAL1/GAS6/ACE/FBXW7/ADRA2A/CHMP6/NTRK2/EGF/CBL/AFAP1L2/IBTK/NEDD9/THY1/NOX4/CAV1/PTPRC	20
BP	GO:1903725	regulation of phospholipid metabolic process	20/2486	88/18670	0.01065	0.07512	0.05888	SOCS7/ARF1/FLT1/TGFB1/P2RY12/APOC1/GNB3/PDGFRA/KLF4/PDGFRB/TEK/CCL21/WDR91/VAV3/DGKZ/LYN/MTMR4/NR1H4/FABP3/LPCAT1	20
BP	GO:1904035	regulation of epithelial cell apoptotic process	20/2486	88/18670	0.01065	0.07512	0.05888	PDPK1/TNFAIP3/ITGA4/TNF/ZFP36/GAS6/EIF2S1/ANGPTL4/COL18A1/ECSCR/RAMP2/PAK4/SFRP4/NUPR1/TEK/CD248/CAPN10/MTOR/KDR/WFS1	20
BP	GO:0050921	positive regulation of chemotaxis	28/2486	135/18670	0.01066	0.07512	0.05888	SUCNR1/NTF3/CSF1/VEGFC/AKIRIN1/TGFB1/NRP1/GAS6/P2RY12/FGF18/EDN3/THBS4/HSPB1/RARRES2/SMOC2/CXCL12/DAPK2/PTN/IL12A/PDGFRB/STX4/CCL21/TREM2/PPM1F/WNT5A/SLIT2/KDR/ITGA2	28
BP	GO:0010761	fibroblast migration	11/2486	39/18670	0.01077	0.07559	0.05924	TNS1/BAG4/C5orf30/TGFB1/CYGB/ARHGEF7/PML/TMEM201/PAK3/HAS1/DDR2	11
BP	GO:0030501	positive regulation of bone mineralization	11/2486	39/18670	0.01077	0.07559	0.05924	ACVR1/TMEM119/LTF/TGFB1/BMP2/FBN2/P2RX7/ACVR2A/PTN/PKDCC/KL	11
BP	GO:1901998	toxin transport	11/2486	39/18670	0.01077	0.07559	0.05924	RAB28/ARID1A/SCFD1/DNAJA1/COPB2/NRP1/DNM1/CCT8/MTMR12/HSPA5/LRP5	11
BP	GO:0071453	cellular response to oxygen levels	44/2486	234/18670	0.01077	0.07559	0.05924	SIRT2/PSMD14/PMAIP1/PSMD12/DDAH1/PPARG/EP300/TWIST1/NOL3/PSMD7/PINK1/PSMB5/PHB2/HYOU1/UBA52/CACNB3/ATP6V0A2/MIR21/CREBBP/SIRT1/MDM4/STC1/TBL2/CHCHD2/PTN/CBL/PLK3/AQP1/PSMB7/CPEB1/KCNK3/TMEM199/CD34/NOTCH1/PSMD1/SFRP1/PSMD9/UBC/MIR214/CAV1/STC2/MTOR/PSME1/CPEB2	44
BP	GO:0048017	inositol lipid-mediated signaling	36/2486	184/18670	0.01083	0.07573	0.05936	SIRT2/NTF3/SLC9A3R1/PEAR1/PTPN13/TNF/TWIST1/FLT1/TGFB2/SELP/MIR21/IER3/IGF1R/GPR143/SIRT1/EGFR/NTRK2/SEMA4D/IGF1/PLCB2/PLCB1/PDGFRA/CBL/CEACAM1/IRS2/PIK3CD/KLF4/PDGFRB/HCST/SOX9/TEK/DCN/HCLS1/INPP5F/LYN/KDR	36
BP	GO:0006409	tRNA export from nucleus	10/2486	34/18670	0.01085	0.07573	0.05936	NUP93/NUP50/NUP153/NUP210/RAE1/NUP188/NUP160/NUP54/NUP214/NUP155	10
BP	GO:0007435	salivary gland morphogenesis	10/2486	34/18670	0.01085	0.07573	0.05936	POLB/TNF/TGFB2/TGFB1/NRP1/TWSG1/NFIB/EGFR/PLXNA1/NTN4	10
BP	GO:0032148	activation of protein kinase B activity	10/2486	34/18670	0.01085	0.07573	0.05936	NTF3/PDPK1/PINK1/GAS6/ADRA2A/MIR21/IGF1/WNT5A/MTOR/MAPKAP1	10
BP	GO:0071431	tRNA-containing ribonucleoprotein complex export from nucleus	10/2486	34/18670	0.01085	0.07573	0.05936	NUP93/NUP50/NUP153/NUP210/RAE1/NUP188/NUP160/NUP54/NUP214/NUP155	10
BP	GO:0046394	carboxylic acid biosynthetic process	79/2486	462/18670	0.011	0.0767	0.06012	OSBP/OSBPL6/DHRS9/SLC4A1/PLOD2/HPGD/HSD3B7/FABP5/LPL/NUP93/OLAH/SEPHS2/SLC1A3/CDO1/TGFB1/CH25H/PFKFB2/GGT5/PLA2G5/MGLL/LDHC/THNSL2/ERLIN1/DHTKD1/SMPD3/UGP2/ZBTB7A/NUP50/APOC1/PYCR1/OXSM/SIRT1/GCH1/P2RX7/ERLIN2/CBFA2T3/IGF1/OSBPL9/ADIPOR2/NUP153/LIAS/NUP210/EGF/ELOVL7/ASS1/SERINC3/RAE1/NUP188/CEACAM1/NUP160/BGN/NUP54/NUP214/NUP155/FOXK2/HAS2/NUPR1/SLC2A6/PRKAG2/ALDH1A3/IL1B/CPS1/ALDH1A2/HAS3/DCN/AKR1D1/WDTC1/HAS1/HPGDS/CSPG4/CYP39A1/RBP1/PDK4/NR1H4/HYAL1/ELOVL5/MTHFR/ABAT/PFKP	79
BP	GO:0021543	pallium development	34/2486	172/18670	0.01116	0.07768	0.06088	ANXA3/TRA2B/FGF13/CCDC85C/LHX6/PLXNA3/TACC1/SCT/CRKL/KDM6B/NRP1/P2RY12/EGFR/NTRK2/PLCB1/CDON/SMO/SLC32A1/MFSD2A/KCNA1/GLI3/BTG2/LAMB1/CDK5R1/FLNA/NDE1/EMX2/GNG12/SLIT2/EZH1/TACC2/SUN2/KIF14/NCOA1	34
BP	GO:0120034	positive regulation of plasma membrane bounded cell projection assembly	22/2486	100/18670	0.01125	0.07825	0.06133	EPS8/APC/WASF2/AKIRIN1/AGRN/PLEK2/ANLN/NRP1/P2RY12/FNBP1L/P2RX7/CEP135/DPYSL3/CCL21/NCKAP1/DZIP1/ARPC2/MTOR/PFN1/CDC42EP5/DOCK11/EPS8L1	22
BP	GO:0071214	cellular response to abiotic stimulus	59/2486	331/18670	0.01133	0.0786	0.0616	CRADD/C9orf116/GUCY2D/MME/XRCC6/FADD/YY1/POLE3/EP300/NIPBL/EIF2AK4/IRF1/BCL10/TGFB1/RAB11FIP5/IFI16/PDE2A/EIF2S1/PPID/MAP3K14/CREBBP/BDKRB2/FBXO4/USP28/NFATC4/PTGER4/SIRT1/MAP3K2/EGFR/BCL2L1/SFRP2/MAP3K1/PTN/BMF/TMEM150C/AQP1/HVCN1/SOX9/RCSD1/YAP1/IL1B/SFRP1/REST/NOX4/EFHD1/LRRC8E/PPEF1/TRIAP1/BAK1/TNKS1BP1/METAP1/PDE6G/ITGA2/TAF1/MFAP4/HSPA5/MGMT/CRYAB/HYAL1	59
BP	GO:0104004	cellular response to environmental stimulus	59/2486	331/18670	0.01133	0.0786	0.0616	CRADD/C9orf116/GUCY2D/MME/XRCC6/FADD/YY1/POLE3/EP300/NIPBL/EIF2AK4/IRF1/BCL10/TGFB1/RAB11FIP5/IFI16/PDE2A/EIF2S1/PPID/MAP3K14/CREBBP/BDKRB2/FBXO4/USP28/NFATC4/PTGER4/SIRT1/MAP3K2/EGFR/BCL2L1/SFRP2/MAP3K1/PTN/BMF/TMEM150C/AQP1/HVCN1/SOX9/RCSD1/YAP1/IL1B/SFRP1/REST/NOX4/EFHD1/LRRC8E/PPEF1/TRIAP1/BAK1/TNKS1BP1/METAP1/PDE6G/ITGA2/TAF1/MFAP4/HSPA5/MGMT/CRYAB/HYAL1	59
BP	GO:0010952	positive regulation of peptidase activity	38/2486	197/18670	0.01135	0.07867	0.06166	PSMD14/PMAIP1/CRADD/MBP/FADD/PPARG/TBC1D10A/CASP4/RPS27L/SNCA/TNF/BCL10/PCOLCE2/PINK1/IFI16/MIR21/FN1/SIRT1/ASPH/SFRP2/PML/MAP3K5/PCOLCE/VCP/PRR7/DIABLO/NLRP1/REST/PPM1F/FBLN1/CAV1/LYN/DLC1/BAK1/PDCD5/PSME1/ANP32B/CIDEB	38
BP	GO:0051785	positive regulation of nuclear division	16/2486	66/18670	0.01142	0.0789	0.06184	SIRT2/NIPBL/SMC5/TGFB1/PHB2/SMPD3/EDN3/IGF1/EGF/PLCB1/PDGFRB/UBE2C/IL1B/WNT5A/MSX1/LRP5	16
BP	GO:0072171	mesonephric tubule morphogenesis	16/2486	66/18670	0.01142	0.0789	0.06184	PBX1/DLG1/TGFB1/HES1/BMP2/NPNT/SIX1/HOXB7/SMO/SOX9/GLI3/HOXA11/ADAMTS16/SIX2/GZF1/LZTS2	16
BP	GO:1904888	cranial skeletal system development	16/2486	66/18670	0.01142	0.0789	0.06184	NIPBL/TWIST1/TGFB2/CRKL/TGFB1/WDR19/FOXN3/SIX1/PDGFRA/PRRX1/IFT140/GLI3/TBX15/TBX1/SIX2/SETD2	16
BP	GO:0021915	neural tube development	32/2486	160/18670	0.01143	0.0789	0.06184	ARID1A/TWIST1/BCL10/TGFB2/TGFB1/PHACTR4/HES1/LUZP1/WDR19/TRAF6/SFRP2/LIAS/STK4/SEC24B/SMO/IFT140/NOTCH1/GLI3/CTHRC1/SFRP1/C2CD3/ALDH1A2/FKBP8/WNT5A/SSBP3/RPS7/DLC1/INTU/PFN1/SPINT2/SETD2/MTHFR	32
BP	GO:0002456	T cell mediated immunity	23/2486	106/18670	0.01146	0.07897	0.06189	FAM49B/CD1C/FADD/ARG1/SMAD7/DLG1/IL1R1/FBXO38/FCGR2B/CD1B/TRAF6/IL23R/P2RX7/HLA-B/CEACAM1/IL12A/EMP2/IL1B/PPP3CB/FZD5/PTPRC/RSAD2/HLA-A	23
BP	GO:0010770	positive regulation of cell morphogenesis involved in differentiation	31/2486	154/18670	0.01155	0.07951	0.06232	MYADM/OLFM4/BDNF/TRAK1/PLXNA3/LIMS2/CRKL/CUX2/RND2/NRP1/L1CAM/FBXW8/FN1/ARHGEF7/NTRK2/SEMA4D/OBSL1/SKIL/CXCL12/NIN/HAS2/SHOX2/PLXNA1/NEDD9/LIMS1/RREB1/PAK3/FLNA/ARPC2/SLIT2/GDI1	31
BP	GO:0016053	organic acid biosynthetic process	79/2486	463/18670	0.01158	0.07966	0.06243	OSBP/OSBPL6/DHRS9/SLC4A1/PLOD2/HPGD/HSD3B7/FABP5/LPL/NUP93/OLAH/SEPHS2/SLC1A3/CDO1/TGFB1/CH25H/PFKFB2/GGT5/PLA2G5/MGLL/LDHC/THNSL2/ERLIN1/DHTKD1/SMPD3/UGP2/ZBTB7A/NUP50/APOC1/PYCR1/OXSM/SIRT1/GCH1/P2RX7/ERLIN2/CBFA2T3/IGF1/OSBPL9/ADIPOR2/NUP153/LIAS/NUP210/EGF/ELOVL7/ASS1/SERINC3/RAE1/NUP188/CEACAM1/NUP160/BGN/NUP54/NUP214/NUP155/FOXK2/HAS2/NUPR1/SLC2A6/PRKAG2/ALDH1A3/IL1B/CPS1/ALDH1A2/HAS3/DCN/AKR1D1/WDTC1/HAS1/HPGDS/CSPG4/CYP39A1/RBP1/PDK4/NR1H4/HYAL1/ELOVL5/MTHFR/ABAT/PFKP	79
BP	GO:0048145	regulation of fibroblast proliferation	19/2486	83/18670	0.01165	0.07998	0.06269	PPARG/JUN/DHX9/TGFB1/CREB1/GAS6/FN1/FBXO4/EGFR/PML/IGF1/PDGFRA/AQP1/PDGFRB/NUPR1/SFRP1/WNT5A/CD300A/DDR2	19
BP	GO:2000106	regulation of leukocyte apoptotic process	19/2486	83/18670	0.01165	0.07998	0.06269	ARG2/FADD/BCL10/GAS6/BTK/SIRT1/P2RX7/CXCL12/MIR17HG/IRS2/PIK3CD/IL2/CCL21/WNT5A/HCLS1/LYN/TSC22D3/DOCK8/AXL	19
BP	GO:0038127	ERBB signaling pathway	29/2486	142/18670	0.01171	0.08002	0.06272	SPRY2/NRG4/PDPK1/TGFB1/SPRY1/FBXW7/ADRA2A/HSP90AA1/MIR21/CHMP6/ARHGEF7/EGFR/RHBDF1/PIGR/EGF/CBL/CEACAM1/MMP9/DGKD/BCAR1/AFAP1L2/SOX9/IFI6/CAMLG/EFEMP1/SH3TC2/PDE6G/RPS6KA5/RASSF2	29
BP	GO:1900542	regulation of purine nucleotide metabolic process	29/2486	142/18670	0.01171	0.08002	0.06272	PDPR/SLC25A33/SNCA/NUP93/PINK1/PFKFB2/FLCN/ZBTB7A/NUP50/NOS3/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/VCP/RAE1/NUP188/COX7A1/NUP160/NUP54/PDP1/NUP214/NUP155/NUPR1/SLC2A6/PRKAG2/TREM2/PDK4	29
BP	GO:0006525	arginine metabolic process	7/2486	20/18670	0.01172	0.08002	0.06272	DDAH1/ARG2/ARG1/MIR21/NOS3/ASS1/CPS1	7
BP	GO:0046931	pore complex assembly	7/2486	20/18670	0.01172	0.08002	0.06272	TMEM170A/NUP93/PLEKHA7/P2RX7/NUP153/CCT8/PDZD11	7
BP	GO:0060216	definitive hemopoiesis	7/2486	20/18670	0.01172	0.08002	0.06272	GATA1/TAL1/HIPK1/SP3/TEK/MFAP5/HOXA9	7
BP	GO:0006417	regulation of translation	73/2486	424/18670	0.01208	0.08234	0.06454	ENC1/RBM4/MKNK2/EIF5/TSFM/PPP1R15A/PPP1R15B/EIF5A/CNOT8/PAIP2B/RPS27L/EIF4B/EIF2AK4/TNF/YTHDF2/NGDN/SARNP/FXR1/IREB2/DHX9/PINK1/SERP1/TNRC6B/ZFP36/EIF2S1/RBM3/LARP1/RPLP1/NOLC1/MIR21/EIF1/ZC3H12A/PAIP2/ILF3/RPL10/YTHDF1/SESN2/EIF2A/HSPB1/EIF4H/POLR2G/DNAJC24/IGFBP5/CELF1/TACO1/CPEB1/PRR16/DIO2/BTG2/KHDRBS1/MIF4GD/YTHDF3/RNF139/MRPL13/EIF3K/RMND1/CNOT7/PCIF1/MAPKAPK5/RBMS3/MTOR/METAP1/ITGA2/CDC123/UHMK1/POLR2D/RC3H1/PER1/TCOF1/EIF2B2/CNOT1/LARP6/CPEB2	73
BP	GO:0045137	development of primary sexual characteristics	42/2486	223/18670	0.01216	0.0828	0.0649	MAMLD1/INHBA/GATA1/RAB13/TAF4/TGFB2/CRKL/SAFB2/ARID4A/TIPARP/CCND1/FOXC1/WDR19/SIRT1/BCL2L1/NOS3/SFRP2/ACVR2A/PDGFRA/CBL/HOXA10/MMP19/PDGFRB/NUPR1/SOX9/HOXA11/SFRP1/RXFP2/ZFPM2/NUP210L/WNT5A/FLNA/HMGCS1/SLIT2/HOXA9/ADCYAP1/FZD4/HSPA5/EIF2B2/LHX8/ZNF830/NCOA1	42
BP	GO:0034113	heterotypic cell-cell adhesion	15/2486	61/18670	0.01232	0.08375	0.06564	ITGB3/NRCAM/GLDN/MBP/ITGA4/MYADM/TNF/ITGA7/JUP/CEACAM6/KLF4/IL1B/THY1/PTPRC/PARVA	15
BP	GO:0042733	embryonic digit morphogenesis	15/2486	61/18670	0.01232	0.08375	0.06564	TWIST1/B9D1/CREBBP/LMBR1/SFRP2/IFT140/TBX2/NOTCH1/GLI3/HOXA11/C2CD3/WNT5A/MSX1/INTU/TMEM231	15
BP	GO:0002820	negative regulation of adaptive immune response	12/2486	45/18670	0.0126	0.08534	0.06689	PARP3/ARG1/SMAD7/FCGR2B/ZC3H12A/CEACAM1/IL2/TNFRSF14/IL33/PPP3CB/RC3H1/PTPRC	12
BP	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	12/2486	45/18670	0.0126	0.08534	0.06689	MUC1/EP300/RPS27L/HIPK1/IFI16/PHLDA3/USP28/SIRT1/PML/HNRNPK/NUPR1/TRIAP1	12
BP	GO:0048483	autonomic nervous system development	12/2486	45/18670	0.0126	0.08534	0.06689	EDNRB/KIF26A/NAV2/PLXNA3/PHACTR4/HES1/NRP1/ADARB1/FN1/HLX/SIX1/TBX1	12
BP	GO:0006352	DNA-templated transcription, initiation	46/2486	249/18670	0.0127	0.08593	0.06735	TFAM/BCLAF1/MED10/PPARG/GTF2I/TBX5/TAF4/TAF10/TWIST1/JUN/CDK9/MED8/RXRB/PPM1D/CREB1/GTF2H3/MED7/CCND1/CREBBP/THRB/MED13/GTF3C4/WWTR1/MED6/POLR2G/TAF3/RSF1/NR1D2/MED30/TEAD4/SOX9/NAT14/NOTCH1/NOTCH2/YAP1/NR2F6/GTF2E1/NR3C1/NR4A2/BDP1/TAF1/POLR2D/NCOA6/NOTCH3/NR1H4/NR5A2	46
BP	GO:0043407	negative regulation of MAP kinase activity	18/2486	78/18670	0.01274	0.08595	0.06737	SPRY2/SH2B3/DUSP10/PPP2CA/DNAJA1/SORL1/SPRY1/SFRP2/SPRY4/UCHL1/IL1B/SFRP1/DUSP1/CD300A/CAV1/LYN/DUSP18/RGS14	18
BP	GO:0070664	negative regulation of leukocyte proliferation	18/2486	78/18670	0.01274	0.08595	0.06737	INPP5D/TNFAIP3/ARG2/ARG1/DLG1/TGFB1/FCGR2B/TWSG1/BTK/PDCD1LG2/IL2/TNFRSF14/GPNMB/CCL8/CD300A/LYN/SPN/RC3H1	18
BP	GO:1903313	positive regulation of mRNA metabolic process	18/2486	78/18670	0.01274	0.08595	0.06737	TRA2B/CNOT8/YTHDF2/TNRC6B/ZFP36/SF3B4/RBM3/ZC3H12A/RBMXL1/POLR2G/TRA2A/CPEB1/BTG2/RBMX/YTHDF3/CNOT7/RC3H1/CNOT1	18
BP	GO:1903900	regulation of viral life cycle	30/2486	149/18670	0.01277	0.08603	0.06743	IFI27/SLPI/STOM/TRIM6/EIF2AK4/CAV2/TNF/LTF/IFITM3/TRIM21/IFI16/TNIP1/ADARB1/SRPK2/PPID/LARP1/ZC3H12A/ILF3/PML/VPS37B/IFIT1/IFIT5/NOTCH1/IFITM2/PKN2/CCL8/CNOT7/STAU1/RSAD2/NR5A2	30
BP	GO:0030330	DNA damage response, signal transduction by p53 class mediator	23/2486	107/18670	0.0128	0.08616	0.06753	MUC1/PMAIP1/CRADD/CNOT8/CNOT4/EP300/RPS27L/TWIST1/USP10/PPM1D/SIRT1/MDM4/SESN2/BATF/PML/PLK3/BTG2/MSX1/CNOT7/TRIAP1/TNKS1BP1/E2F8/CNOT1	23
BP	GO:0003071	renal system process involved in regulation of systemic arterial blood pressure	8/2486	25/18670	0.01293	0.08667	0.06793	SUCNR1/PTPRO/CYP4F2/GAS6/GJA5/HSD11B2/AGTR1/EMP2	8
BP	GO:0019054	modulation by virus of host process	8/2486	25/18670	0.01293	0.08667	0.06793	EIF2AK4/ZC3H12A/KPNA1/BCL2L1/PABPN1/KPNA3/CCL8/KPNA4	8
BP	GO:0021680	cerebellar Purkinje cell layer development	8/2486	25/18670	0.01293	0.08667	0.06793	FAIM2/HERC1/B4GALT2/LDB1/AGTPBP1/MYH10/HSPA5/KIF14	8
BP	GO:0051894	positive regulation of focal adhesion assembly	8/2486	25/18670	0.01293	0.08667	0.06793	NRP1/COL16A1/TEK/SFRP1/THY1/LIMS1/PPM1F/KDR	8
BP	GO:1903532	positive regulation of secretion by cell	69/2486	399/18670	0.01305	0.08734	0.06845	SRI/ORM1/SYTL4/MMP8/CD177/MBP/INHBA/ARF1/MAPK11/TRIM6/SNCA/TNF/TWIST1/LPL/GHRL/TGFB2/SCT/FRMD4A/VEGFC/DHX9/CD244/TGFB1/PINK1/SERP1/TRH/PFKFB2/CREB1/C2CD2L/CLASP2/STXBP1/PPID/SMPD3/PTGER4/EDN3/SPP1/TM7SF3/EGFR/IFIH1/P2RX7/IGF1/CXCL12/CADPS2/IRS2/C1QTNF1/IL2/TNFRSF14/CD34/IL1B/STX4/IL33/TREM2/PPP3CB/PSMD9/FZD5/NLRP1/OXTR/WNT5A/IL26/PARD6A/CAPN10/CLASP1/POSTN/ADCYAP1/FRMD8/MYH10/UNC13B/NR1H4/ABAT/NLRP7	69
BP	GO:0030595	leukocyte chemotaxis	42/2486	224/18670	0.01309	0.08746	0.06855	CXCL5/EDNRB/PTPRO/CSF1/LYST/FLT1/HSD3B7/TGFB2/VEGFC/AKIRIN1/CH25H/GAS6/CX3CL1/CXCR1/PDE4B/EDN3/THBS4/CCL13/VAV1/RARRES2/ITGA9/CXCL12/DAPK2/MTUS1/PTN/CXCL6/TNFRSF11A/PIK3CD/HRH1/IL12A/IL1B/CCL21/CXCL1/VAV3/WNT5A/CCL8/DUSP1/SLIT2/LYN/MST1/CORO1A/CCL18	42
BP	GO:0001990	regulation of systemic arterial blood pressure by hormone	11/2486	40/18670	0.01311	0.08746	0.06855	SUCNR1/MME/CTSG/ACE/GJA5/EDN3/HSD11B2/NOS3/AGTR1/OXTR/ENPEP	11
BP	GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	11/2486	40/18670	0.01311	0.08746	0.06855	PARP3/ARG1/SMAD7/FCGR2B/ZC3H12A/CEACAM1/IL2/IL33/PPP3CB/RC3H1/PTPRC	11
BP	GO:0010506	regulation of autophagy	58/2486	327/18670	0.01318	0.0877	0.06874	SIRT2/RRAGA/CTTN/SCFD1/VPS13C/ITPR1/HERC1/EP300/ATP6V1E1/EIF2AK4/SNCA/USP10/PINK1/TRIM21/IFI16/FBXW7/ERN1/LARP1/ATP6V0A2/FLCN/ZC3H12A/RAB3GAP2/SIRT1/SESN2/DDIT3/SMCR8/HSPB1/UCHL1/ULK2/DAPK2/EEF1A1/FYCO1/WAC/BMF/SESN3/TMEM150C/PLK3/FOXK2/MCL1/MTM1/NUPR1/LRSAM1/PRKAG2/RAB12/TREM2/FZD5/CDK5R1/UVRAG/DCN/USP33/VPS26B/IL10RA/MTOR/KDR/GPSM1/RAB8A/HSPB8/SCOC	58
BP	GO:0009416	response to light stimulus	56/2486	314/18670	0.01319	0.0877	0.06874	RBM4/MSH6/C9orf116/GUCY2D/MME/JUND/YY1/EP300/EIF2AK4/B4GALT2/UNC119/SLC1A3/ELANE/BHLHE40/CREB1/ZRANB3/EIF2S1/CCND1/PPID/CREBBP/ABCA4/SCARA3/FOS/USP28/NFATC4/SIRT1/EGFR/MEIS2/PML/RELA/UBE4B/SEMA5B/PTN/MTA1/NPHP1/HRH1/IL12A/BMF/AQP1/DYNLRB1/POLG/NR2F6/DUSP1/HMGCS1/MTOR/PPEF1/TRIAP1/BAK1/RGS14/METAP1/PDE6G/TAF1/GNGT2/MFAP4/PER1/HYAL1	56
BP	GO:1903391	regulation of adherens junction organization	16/2486	67/18670	0.0132	0.0877	0.06874	ARHGAP6/LDB1/NRP1/CLASP2/COL16A1/PHLDB2/TEK/SFRP1/THY1/LIMS1/PPM1F/FAM107A/CLASP1/DLC1/KDR/LIMCH1	16
BP	GO:0048144	fibroblast proliferation	19/2486	84/18670	0.01323	0.0877	0.06874	PPARG/JUN/DHX9/TGFB1/CREB1/GAS6/FN1/FBXO4/EGFR/PML/IGF1/PDGFRA/AQP1/PDGFRB/NUPR1/SFRP1/WNT5A/CD300A/DDR2	19
BP	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	14/2486	56/18670	0.01324	0.0877	0.06874	MUC1/CRADD/CNOT8/CNOT4/EP300/MDM4/PML/PLK3/BTG2/CNOT7/TRIAP1/TNKS1BP1/E2F8/CNOT1	14
BP	GO:0060688	regulation of morphogenesis of a branching structure	14/2486	56/18670	0.01324	0.0877	0.06874	BCL11A/TNF/TGFB1/PHB2/SIX1/HOXB7/SULF1/SMO/SOX9/SHOX2/SFRP1/WNT5A/SIX2/NTN4	14
BP	GO:0070936	protein K48-linked ubiquitination	14/2486	56/18670	0.01324	0.0877	0.06874	IFI27/TNFAIP3/RNF6/ARIH2/ITCH/FBXO38/RNF216/DTX3L/UBE2C/SKP2/UBE2D3/UBE2G2/RNF8/TRIM44	14
BP	GO:0006936	muscle contraction	63/2486	360/18670	0.01341	0.08806	0.06902	SRI/MYL9/SCN1B/CTTN/SLC6A8/ITGB5/EDNRB/ARG2/TMOD1/MYL6B/MYL4/SMAD7/DLG1/GHRL/TPM1/ACTG2/TACR1/ADRA2A/GJA5/MIR21/ZC3H12A/CALD1/PDE4B/GRIP2/BDKRB2/SGCD/EDN3/ASPH/JUP/CALCRL/KCND3/STAC/STC1/NPNT/OBSL1/STAC2/PABPN1/UTRN/KCNA5/LMOD1/SULF1/SSPN/KCNMA1/FXYD1/NUP155/KCNJ8/RCSD1/KCNA1/SMTN/FKBP1B/HSPB6/SORBS1/ANK2/OXTR/FLNA/RYR2/CAV1/MTOR/ITGA2/DMD/ACTA2/CRYAB/ABAT	63
BP	GO:0001782	B cell homeostasis	9/2486	30/18670	0.01342	0.08806	0.06902	TNFAIP3/PPP2R3C/BCL10/MIR17HG/GAPT/LYN/BAK1/RC3H1/DOCK11	9
BP	GO:0003209	cardiac atrium morphogenesis	9/2486	30/18670	0.01342	0.08806	0.06902	ACVR1/TBX5/TGFB2/GJA5/SMO/NOTCH1/SHOX2/NOTCH2/WNT5A	9
BP	GO:0048873	homeostasis of number of cells within a tissue	9/2486	30/18670	0.01342	0.08806	0.06902	GATA1/CSF1/LIPA/NOS3/P2RX7/SMO/SOX9/NOTCH1/CORO1A	9
BP	GO:0070168	negative regulation of biomineral tissue development	9/2486	30/18670	0.01342	0.08806	0.06902	GATA1/BCOR/TGFB1/GAS6/ECM1/NOS3/SOX9/NOTCH1/ASPN	9
BP	GO:0090200	positive regulation of release of cytochrome c from mitochondria	9/2486	30/18670	0.01342	0.08806	0.06902	PMAIP1/MFF/PINK1/MOAP1/MMP9/BMF/BAK1/PDCD5/CIDEB	9
BP	GO:0035909	aorta morphogenesis	10/2486	35/18670	0.01342	0.08806	0.06902	TGFB2/HES1/ADAMTS9/SIX1/EFNB2/SEC24B/PDGFRB/TBX2/NOTCH1/TBX1	10
BP	GO:0060338	regulation of type I interferon-mediated signaling pathway	10/2486	35/18670	0.01342	0.08806	0.06902	FADD/TRIM6/YTHDF2/SAMHD1/MIR21/WNT5A/YTHDF3/CNOT7/HSP90AB1/ABCE1	10
BP	GO:0001977	renal system process involved in regulation of blood volume	6/2486	16/18670	0.01347	0.08806	0.06902	PTPRO/CYP4F2/GAS6/GJA5/HSD11B2/EMP2	6
BP	GO:0030889	negative regulation of B cell proliferation	6/2486	16/18670	0.01347	0.08806	0.06902	INPP5D/FCGR2B/BTK/CD300A/LYN/RC3H1	6
BP	GO:0060413	atrial septum morphogenesis	6/2486	16/18670	0.01347	0.08806	0.06902	ACVR1/TBX5/TGFB2/GJA5/SMO/NOTCH2	6
BP	GO:0060628	regulation of ER to Golgi vesicle-mediated transport	6/2486	16/18670	0.01347	0.08806	0.06902	SCFD1/ARF1/GAS1/SORL1/SEC24B/RNF139	6
BP	GO:0019217	regulation of fatty acid metabolic process	21/2486	96/18670	0.01391	0.09075	0.07112	PDPR/PPARG/SNCA/TWIST1/FABP5/ERLIN1/APOC1/SIRT1/ERLIN2/ADIPOR2/CEACAM1/IRS2/PDP1/PRKAG2/IL1B/WDTC1/CAV1/MTOR/PDK4/FABP3/ELOVL5	21
BP	GO:0072401	signal transduction involved in DNA integrity checkpoint	17/2486	73/18670	0.01392	0.09075	0.07112	MUC1/CRADD/CNOT8/CNOT4/EP300/MIR21/MDM4/PML/PLK3/PLK1/BTG2/CNOT7/TRIAP1/TNKS1BP1/E2F8/CDC5L/CNOT1	17
BP	GO:0072422	signal transduction involved in DNA damage checkpoint	17/2486	73/18670	0.01392	0.09075	0.07112	MUC1/CRADD/CNOT8/CNOT4/EP300/MIR21/MDM4/PML/PLK3/PLK1/BTG2/CNOT7/TRIAP1/TNKS1BP1/E2F8/CDC5L/CNOT1	17
BP	GO:0071322	cellular response to carbohydrate stimulus	29/2486	144/18670	0.01413	0.09199	0.0721	SRI/LRP5L/TRA2B/SLC2A5/CDK16/PRKCB/GHRL/RAB11FIP5/C2CD2L/GAS6/ERN1/ADRA2A/RAF1/IGF1R/JAGN1/CALCRL/GJB6/IRS2/SLC26A6/POLG/STX4/FKBP1B/PPP3CB/NOX4/COLEC12/UNC13B/NR1H4/LRP5/SIN3A	29
BP	GO:0031103	axon regeneration	13/2486	51/18670	0.01416	0.092	0.0721	RGMA/JUN/RTN4RL1/STK24/SPP1/PTN/PTPRF/LRIG2/KLF4/GAP43/FKBP1B/INPP5F/TNC	13
BP	GO:0048146	positive regulation of fibroblast proliferation	13/2486	51/18670	0.01416	0.092	0.0721	JUN/DHX9/TGFB1/GAS6/FN1/EGFR/PML/IGF1/PDGFRA/AQP1/PDGFRB/WNT5A/DDR2	13
BP	GO:0008584	male gonad development	28/2486	138/18670	0.01424	0.09246	0.07247	MAMLD1/INHBA/GATA1/RAB13/TGFB2/CRKL/SAFB2/ARID4A/CCND1/BCL2L1/SFRP2/ACVR2A/PDGFRA/CBL/HOXA10/PDGFRB/NUPR1/SOX9/HOXA11/SFRP1/RXFP2/ZFPM2/NUP210L/WNT5A/FLNA/HMGCS1/HOXA9/NCOA1	28
BP	GO:0007548	sex differentiation	49/2486	270/18670	0.01431	0.09249	0.07249	MAMLD1/INHBA/GATA1/NIPBL/RAB13/PBX1/TAF4/TGFB2/CRKL/SAFB2/FKBP4/ARID4A/TIPARP/CCND1/FOXC1/WDR19/SIRT1/BCL2L1/NOS3/SFRP2/DMRT3/ACVR2A/PDGFRA/CBL/HOXA10/MMP19/PDGFRB/NUPR1/SOX9/HOXA11/SFRP1/RXFP2/ZFPM2/NUP210L/WNT5A/FLNA/HMGCS1/SLIT2/HSD17B3/HOXA9/BAK1/ADCYAP1/FZD4/HSPA5/AXL/EIF2B2/LHX8/ZNF830/NCOA1	49
BP	GO:0042177	negative regulation of protein catabolic process	27/2486	132/18670	0.01433	0.09249	0.07249	SIRT2/GABARAPL2/SNCA/UBXN1/SMARCC1/USP7/MDM4/EGFR/PML/RELA/WAC/TIMP3/LRIG2/BANP/MTM1/LAPTM4B/CAMLG/TIMP4/UBE2G2/FLNA/AZIN1/HSP90AB1/RPS7/TAF1/MYCBP2/GIPC1/PIN1	27
BP	GO:0030218	erythrocyte differentiation	24/2486	114/18670	0.01436	0.09249	0.07249	ALAS2/KLF13/SH2B3/EPB42/INPP5D/SLC4A1/INHBA/GATA1/L3MBTL3/TRIM58/TAL1/LDB1/AHSP/ZFP36/ARID4A/ZBTB7A/SP3/ACVR2A/JMJD6/HCLS1/LYN/KLF1/SOX6/HSPA9	24
BP	GO:0016569	covalent chromatin modification	80/2486	474/18670	0.01437	0.09249	0.07249	MUC1/SIRT2/RBM14/PHF20/UTY/NCOA3/RLF/POLE3/MSL2/EP300/BCOR/AKAP8L/NIPBL/PRDM6/PRKCB/SNCA/KDM5D/TAF10/TWIST1/SFPQ/HAT1/YEATS2/TGFB1/PINK1/CDK9/LDB1/ING3/KDM6B/ARID4A/BRMS1L/CHD1/WDR5/FLCN/CREBBP/HSF4/KDM2A/IRF4/TRRAP/GTF3C4/USP7/SIRT1/SETD5/MTA1/WAC/JMJD6/RSF1/SETD1B/NSD1/MORF4L2/HCFC1/MCM3AP/JMJD1C/DTX3L/PRDM5/JARID2/IL1B/WDR70/REST/EP400/SUDS3/PPM1F/SIRT7/CHD5/AKAP8/PCGF2/CTCFL/EZH1/SIN3B/SET/TAF1/RPS6KA5/EPC1/PER1/NR1H4/SETD2/SIN3A/MTHFR/RNF8/NCOA1/ING5	80
BP	GO:0010921	regulation of phosphatase activity	34/2486	175/18670	0.01438	0.09249	0.07249	SPOCD1/SH2D4A/PPP1R15A/PPP1R15B/BAG4/HSP90B1/TNF/TGFB2/PHACTR4/PCDH11X/DLG2/CEP192/RCAN2/BMP2/PPP2R5E/CCDC8/SEMA4D/NPNT/PTN/TMEM225/FARP1/PDGFRB/FKBP1B/ELL/MAGI2/CD300A/PCIF1/HSP90AB1/MTOR/SET/ITGA2/STYXL1/PTPRC/IGFBP3	34
BP	GO:0060070	canonical Wnt signaling pathway	59/2486	335/18670	0.01438	0.09249	0.07249	LRP5L/PSMD14/PSMD12/SLC9A3R1/FAM53B/PTPRO/APC/PLEKHA4/WNT5B/PSMD7/TCF7L1/PSMB5/IGFBP2/DAAM2/PRDM15/BMP2/DAB2/DDIT3/WWTR1/JUP/EGFR/CYLD/SFRP2/EGF/VCP/CSNK1A1/IGFBP4/STK4/WNT9A/FZD10/ZBED2/CCNY/SFRP4/PPM1A/RSPO3/PSMB7/KLF4/SOX9/NDP/NOTCH1/YAP1/GLI3/CTHRC1/PSMD1/SFRP1/PSMD9/FZD5/WNT5A/NR4A2/RYR2/CAV1/RBMS3/FZD4/PSME1/RNF220/DKK3/LRP5/LZTS2/PIN1	59
BP	GO:0018107	peptidyl-threonine phosphorylation	26/2486	126/18670	0.01438	0.09249	0.07249	SIRT2/SPRY2/CHI3L1/ACVR1/CIT/PDPK1/TRIM6/PARD3/PRKCB/CLK1/SMAD7/TGFB1/CDC42BPA/HIPK1/PPEF2/EGF/CSNK1A1/TTBK2/PLK1/PRKAG2/CDK5R1/WNT5A/TTK/MTOR/TNKS1BP1/TAF1	26
BP	GO:0032479	regulation of type I interferon production	26/2486	126/18670	0.01438	0.09249	0.07249	TNFAIP3/XRCC6/YY1/EP300/NFKB2/IRF1/LILRA4/DHX9/TRIM21/IFI16/ITCH/GPATCH3/MIR21/CREBBP/REL/PQBP1/IFIH1/CYLD/RELA/RNF216/RNF125/TLR9/PCBP2/SETD2/PIN1/ZCCHC3	26
BP	GO:0072089	stem cell proliferation	25/2486	120/18670	0.0144	0.09249	0.07249	FGF13/DAGLB/YTHDF2/VEGFC/TGFB1/ARIH2/ACE/CX3CL1/NANOG/SFRP2/PTN/SMO/FRS2/CD34/NOTCH1/YAP1/KCNA1/GLI3/NES/FBLN1/WNT5A/NDE1/SIX2/EML1/PTPRC	25
BP	GO:0006110	regulation of glycolytic process	18/2486	79/18670	0.01451	0.09249	0.07249	NUP93/PFKFB2/ZBTB7A/NUP50/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/RAE1/NUP188/NUP160/NUP54/NUP214/NUP155/NUPR1/SLC2A6/PRKAG2	18
BP	GO:0021675	nerve development	18/2486	79/18670	0.01451	0.09249	0.07249	NTF3/ITGA4/NAV2/BDNF/PLXNA3/SLC1A3/HES1/NRP1/ADARB1/SIX1/SULF1/LRIG2/POU4F1/GLI3/TBX1/UNC13B/EPHB2/HOXA3	18
BP	GO:0055072	iron ion homeostasis	18/2486	79/18670	0.01451	0.09249	0.07249	ALAS2/SRI/EPB42/LTF/FXN/IREB2/LCN2/ABCB6/ABCG2/ATP6V0A2/ABCB7/STEAP1/STEAP2/TMEM199/CP/SLC25A37/HEPH/CUL1	18
BP	GO:0006527	arginine catabolic process	5/2486	12/18670	0.01466	0.09249	0.07249	DDAH1/ARG2/ARG1/MIR21/NOS3	5
BP	GO:0006991	response to sterol depletion	5/2486	12/18670	0.01466	0.09249	0.07249	FBXW7/ERLIN1/EIF2A/ERLIN2/LYN	5
BP	GO:0014029	neural crest formation	5/2486	12/18670	0.01466	0.09249	0.07249	PEF1/NOLC1/SOX9/SFRP1/TCOF1	5
BP	GO:0031581	hemidesmosome assembly	5/2486	12/18670	0.01466	0.09249	0.07249	LAMC1/LAMC2/COL17A1/CD151/KRT5	5
BP	GO:0033197	response to vitamin E	5/2486	12/18670	0.01466	0.09249	0.07249	PPARG/ARG1/CCND1/FKBP1B/HMGCS1	5
BP	GO:0033523	histone H2B ubiquitination	5/2486	12/18670	0.01466	0.09249	0.07249	CDK9/WAC/DTX3L/WDR70/RNF8	5
BP	GO:0048934	peripheral nervous system neuron differentiation	5/2486	12/18670	0.01466	0.09249	0.07249	NEFH/NTRK2/POU4F1/ETV1/HOXD9	5
BP	GO:0048935	peripheral nervous system neuron development	5/2486	12/18670	0.01466	0.09249	0.07249	NEFH/NTRK2/POU4F1/ETV1/HOXD9	5
BP	GO:0051873	killing by host of symbiont cells	5/2486	12/18670	0.01466	0.09249	0.07249	CTSG/ARG1/ELANE/CAMP/CXCL6	5
BP	GO:0070486	leukocyte aggregation	5/2486	12/18670	0.01466	0.09249	0.07249	SEMA4D/MSN/STK10/HAS2/IL1B	5
BP	GO:0090331	negative regulation of platelet aggregation	5/2486	12/18670	0.01466	0.09249	0.07249	SH2B3/CD9/CEACAM1/C1QTNF1/ABAT	5
BP	GO:0098885	modification of postsynaptic actin cytoskeleton	5/2486	12/18670	0.01466	0.09249	0.07249	WASF3/CTTNBP2/WASF1/MYH10/PFN1	5
BP	GO:1900376	regulation of secondary metabolite biosynthetic process	5/2486	12/18670	0.01466	0.09249	0.07249	ASIP/MIR21/SLC24A5/WNT5A/GIPC1	5
BP	GO:1904424	regulation of GTP binding	5/2486	12/18670	0.01466	0.09249	0.07249	EIF2S1/ARHGEF7/CSNK1A1/ARHGAP28/GPSM1	5
BP	GO:1905666	regulation of protein localization to endosome	5/2486	12/18670	0.01466	0.09249	0.07249	SORL1/ANKRD13A/MSN/EGF/DTX3L	5
BP	GO:2000341	regulation of chemokine (C-X-C motif) ligand 2 production	5/2486	12/18670	0.01466	0.09249	0.07249	MBP/TNF/LPL/KLF4/POSTN	5
BP	GO:1901532	regulation of hematopoietic progenitor cell differentiation	19/2486	85/18670	0.01497	0.09432	0.07393	PSMD14/PSMD12/GATA1/YTHDF2/PSMD7/TAL1/PSMB5/LDB1/HES1/ITCH/FLCN/FOXC1/PSMB7/NOTCH1/YAP1/PSMD1/PSMD9/PSME1/HSPA9	19
BP	GO:0010639	negative regulation of organelle organization	68/2486	395/18670	0.01501	0.09433	0.07394	CLU/RBM14/EPS8/SCFD1/FGF13/ARHGAP6/TMOD1/BAG4/MYADM/NAV3/CLIP3/APC/BCOR/WASF2/SLC25A5/SNCA/TWIST1/FXN/NOL3/VAT1/PINK1/FKBP4/MTBP/CLASP2/MIR21/FLCN/DCP2/SIRT1/MDM1/BCL2L1/SMCR8/AVIL/IGF1/BUB1B/PHLDB2/MAP2/PFN4/TTBK2/LMOD1/ARHGAP28/PLEKHH2/MID1/PLK1/MTM1/NUPR1/CAPZA1/TMSB4Y/JARID2/TMSB15A/SMG6/MIR214/DUSP1/CDH5/SLIT2/TTK/CLASP1/DLC1/TRIAP1/SET/TMEM67/KANK3/STYXL1/PFN1/CORO1A/PRRT2/SIN3A/NEK2/SHANK3	68
BP	GO:0044003	modification by symbiont of host morphology or physiology	12/2486	46/18670	0.01503	0.09433	0.07394	RRAGA/EIF2AK4/TGFB1/TNIP1/ZC3H12A/KPNA1/BCL2L1/PABPN1/KPNA3/SERPINB9/CCL8/KPNA4	12
BP	GO:0050919	negative chemotaxis	12/2486	46/18670	0.01503	0.09433	0.07394	ITGB3/SEMA3B/PLXNA3/SEMA3G/SEMA4D/SEMA6D/SEMA5B/FLRT2/WNT5A/SLIT2/SEMA3E/SLIT1	12
BP	GO:0060443	mammary gland morphogenesis	12/2486	46/18670	0.01503	0.09433	0.07394	LRP5L/ARG1/CSF1/TGFB1/PHB2/PML/IGFBP5/TBX2/GLI3/WNT5A/CAV1/LRP5	12
BP	GO:0019827	stem cell population maintenance	31/2486	157/18670	0.01509	0.09458	0.07413	ARID1A/NCOA3/MED10/PELO/NIPBL/PBX1/TAL1/LDB1/ZC3H13/HES1/MED7/DPPA4/NANOG/RAF1/POLR2G/PTN/KLF10/MED30/SMO/PRRX1/KLF4/SOX9/NOTCH1/NOTCH2/YAP1/SFRP1/REST/SIX2/POLR2D/DDX6/CNOT1	31
BP	GO:0045639	positive regulation of myeloid cell differentiation	20/2486	91/18670	0.01533	0.09599	0.07523	INPP5D/FADD/INHBA/GATA1/CSF1/TNF/JUN/TRIM58/TGFB1/TAL1/CREB1/FOS/TRAF6/IL23R/ACVR2A/KLF10/POU4F1/RAB7B/TREM2/HCLS1	20
BP	GO:0051055	negative regulation of lipid biosynthetic process	14/2486	57/18670	0.01546	0.09636	0.07552	ORMDL1/FBXW7/ERLIN1/BMP2/APOC1/SIRT1/ERLIN2/CEACAM1/REST/WDTC1/ORMDL2/DKK3/NR1H4/LPCAT1	14
BP	GO:0060760	positive regulation of response to cytokine stimulus	14/2486	57/18670	0.01546	0.09636	0.07552	FADD/CASP4/CSF1/TRIM6/IL1R1/DHX9/GAS6/PARP9/IFIH1/CD300LF/TREM2/WNT5A/AXL/TRIM44	14
BP	GO:0072431	signal transduction involved in mitotic G1 DNA damage checkpoint	14/2486	57/18670	0.01546	0.09636	0.07552	MUC1/CRADD/CNOT8/CNOT4/EP300/MDM4/PML/PLK3/BTG2/CNOT7/TRIAP1/TNKS1BP1/E2F8/CNOT1	14
BP	GO:1902400	intracellular signal transduction involved in G1 DNA damage checkpoint	14/2486	57/18670	0.01546	0.09636	0.07552	MUC1/CRADD/CNOT8/CNOT4/EP300/MDM4/PML/PLK3/BTG2/CNOT7/TRIAP1/TNKS1BP1/E2F8/CNOT1	14
BP	GO:0044773	mitotic DNA damage checkpoint	21/2486	97/18670	0.01559	0.09636	0.07552	MUC1/CRADD/CNOT8/CNOT4/EP300/RPS27L/SYF2/CCND1/MIR21/MDM4/PML/FOXN3/PLK3/BTG2/CNOT7/TRIAP1/TNKS1BP1/E2F8/MUS81/CNOT1/ZNF830	21
BP	GO:0003094	glomerular filtration	7/2486	21/18670	0.0156	0.09636	0.07552	PTPRO/GAS6/GJA5/SULF1/EMP2/CD34/MCAM	7
BP	GO:0003177	pulmonary valve development	7/2486	21/18670	0.0156	0.09636	0.07552	HEYL/TGFB2/GJA5/NOS3/NOTCH1/NOTCH2/SLIT2	7
BP	GO:0032332	positive regulation of chondrocyte differentiation	7/2486	21/18670	0.0156	0.09636	0.07552	FGF18/RELA/SOX9/GLI3/HOXA11/PKDCC/SOX6	7
BP	GO:0036120	cellular response to platelet-derived growth factor stimulus	7/2486	21/18670	0.0156	0.09636	0.07552	CREB1/PTN/CBL/PDGFRB/HAS2/HAS1/HYAL1	7
BP	GO:1900273	positive regulation of long-term synaptic potentiation	7/2486	21/18670	0.0156	0.09636	0.07552	MME/EIF2AK4/SQSTM1/CREB1/STAU1/EPHB2/SHANK3	7
BP	GO:1903055	positive regulation of extracellular matrix organization	7/2486	21/18670	0.0156	0.09636	0.07552	TGFB1/CLASP2/PDPN/PHLDB2/SOX9/DDR2/CLASP1	7
BP	GO:2000316	regulation of T-helper 17 type immune response	7/2486	21/18670	0.0156	0.09636	0.07552	SMAD7/MIR21/ZC3H12A/NFKBIZ/IL23R/IL2/RC3H1	7
BP	GO:2000678	negative regulation of transcription regulatory region DNA binding	7/2486	21/18670	0.0156	0.09636	0.07552	SRI/GATA1/FBXW7/DDIT3/MSX1/TAF1/SIN3A	7
BP	GO:2000737	negative regulation of stem cell differentiation	7/2486	21/18670	0.0156	0.09636	0.07552	TRIM6/HES1/NOTCH1/YAP1/REST/CDK13/HSPA9	7
BP	GO:0072330	monocarboxylic acid biosynthetic process	60/2486	343/18670	0.01563	0.09637	0.07553	OSBP/OSBPL6/DHRS9/SLC4A1/HPGD/HSD3B7/FABP5/LPL/NUP93/OLAH/SLC1A3/CH25H/PFKFB2/MGLL/LDHC/THNSL2/ERLIN1/DHTKD1/ZBTB7A/NUP50/APOC1/OXSM/SIRT1/P2RX7/ERLIN2/CBFA2T3/IGF1/OSBPL9/ADIPOR2/NUP153/LIAS/NUP210/ELOVL7/RAE1/NUP188/CEACAM1/NUP160/BGN/NUP54/NUP214/NUP155/FOXK2/NUPR1/SLC2A6/PRKAG2/ALDH1A3/IL1B/ALDH1A2/DCN/AKR1D1/WDTC1/HPGDS/CSPG4/CYP39A1/RBP1/PDK4/NR1H4/ELOVL5/ABAT/PFKP	60
BP	GO:0046546	development of primary male sexual characteristics	28/2486	139/18670	0.01564	0.09637	0.07553	MAMLD1/INHBA/GATA1/RAB13/TGFB2/CRKL/SAFB2/ARID4A/CCND1/BCL2L1/SFRP2/ACVR2A/PDGFRA/CBL/HOXA10/PDGFRB/NUPR1/SOX9/HOXA11/SFRP1/RXFP2/ZFPM2/NUP210L/WNT5A/FLNA/HMGCS1/HOXA9/NCOA1	28
BP	GO:0002705	positive regulation of leukocyte mediated immunity	27/2486	133/18670	0.01576	0.097	0.07602	FAM49B/CD1C/CD177/FADD/ARG1/TNF/IL1R1/TGFB1/FBXO38/STXBP1/CD1B/DDX21/BTK/EXOSC3/TRAF6/IL23R/VAV1/P2RX7/HLA-B/IL12A/IL2/IL1B/STX4/FZD5/PTPRC/RSAD2/HLA-A	27
BP	GO:0035601	protein deacylation	22/2486	103/18670	0.01577	0.097	0.07602	SIRT2/RBM14/BEX4/EP300/AKAP8L/NIPBL/SFPQ/TGFB1/PINK1/BRMS1L/LYPLAL1/SIRT1/MTA1/MORF4L2/PRDM5/REST/SUDS3/SIRT7/AKAP8/SIN3B/PER1/SIN3A	22
BP	GO:0048738	cardiac muscle tissue development	43/2486	233/18670	0.01581	0.09708	0.07609	ARID1A/ACVR1/YY1/MAPK11/TBX5/SMAD7/TGFB2/TGFB1/TPM1/CREB1/KDM6B/AKAP13/GJA5/SMAD1/FOXC1/BMP2/SGCD/OBSL1/IGF1/ADAMTS9/UBE4B/PDGFRA/MIR17HG/ALPK3/EFNB2/POU4F1/FRS2/PDGFRB/TBX2/NOTCH1/YAP1/JARID2/ALDH1A2/ZFPM2/NOX4/WNT5A/SGCB/RYR2/ALPK2/MTOR/MYH10/SOX6/PIN1	43
BP	GO:0150077	regulation of neuroinflammatory response	11/2486	41/18670	0.01581	0.09708	0.07609	MMP8/TNF/CX3CL1/IGF1/MMP3/MMP9/NUPR1/IL1B/IL33/TREM2/PTPRC	11
BP	GO:0043620	regulation of DNA-templated transcription in response to stress	26/2486	127/18670	0.01586	0.09727	0.07624	MUC1/SIRT2/PSMD14/PSMD12/BCLAF1/EP300/JUN/PSMD7/PSMB5/UBA52/CREBBP/HSF4/SESN2/DDIT3/RELA/PSMB7/CREB3L1/NOTCH1/PSMD1/PSMD9/UBC/RGS14/TAF1/PSME1/HSPA5/SIN3A	26
BP	GO:0072395	signal transduction involved in cell cycle checkpoint	17/2486	74/18670	0.01589	0.09738	0.07632	MUC1/CRADD/CNOT8/CNOT4/EP300/MIR21/MDM4/PML/PLK3/PLK1/BTG2/CNOT7/TRIAP1/TNKS1BP1/E2F8/CDC5L/CNOT1	17
BP	GO:0090276	regulation of peptide hormone secretion	39/2486	208/18670	0.01631	0.09986	0.07827	SRI/LRP5L/SYTL4/ITPR1/CDK16/SLC25A5/CACNA2D2/TNF/GHRL/SCT/SERP1/TRH/PFKFB2/C2CD2L/ICA1/ADRA2A/RAPGEF3/JAGN1/TM7SF3/EGFR/SLC25A6/IRS2/KCNA5/BMP8A/IL1B/STX4/FKBP1B/SFRP1/PPP3CB/PSMD9/REST/CAPN10/ADCYAP1/KCNS3/MIDN/NR1H4/LRP5/RAPGEF4/ABAT	39
BP	GO:0002755	MyD88-dependent toll-like receptor signaling pathway	10/2486	36/18670	0.01642	0.1	0.07839	IRF1/UBA52/TNIP1/BTK/TRAF6/MAP3K1/CD300LF/UBC/TLR9/CD300A	10
BP	GO:0003091	renal water homeostasis	10/2486	36/18670	0.01642	0.1	0.07839	ADCY3/PRKAR2A/ADCY7/CYP4F2/ADCY4/ADCY6/AQP1/HAS2/WFS1/PRKAR2B	10
BP	GO:0010742	macrophage derived foam cell differentiation	10/2486	36/18670	0.01642	0.1	0.07839	ITGB3/PPARG/EP300/NFKBIA/CSF1/LPL/TGFB1/MSR1/AGTR1/PLA2G2A	10
BP	GO:0090077	foam cell differentiation	10/2486	36/18670	0.01642	0.1	0.07839	ITGB3/PPARG/EP300/NFKBIA/CSF1/LPL/TGFB1/MSR1/AGTR1/PLA2G2A	10
BP	GO:0090218	positive regulation of lipid kinase activity	10/2486	36/18670	0.01642	0.1	0.07839	FLT1/TGFB1/P2RY12/PDGFRA/PDGFRB/TEK/CCL21/VAV3/DGKZ/LYN	10
BP	GO:0022617	extracellular matrix disassembly	18/2486	80/18670	0.01645	0.1001	0.07848	MMP8/CTSG/HTRA1/LAMC1/MMP1/TGFB1/ELANE/CLASP2/TPSAB1/PDPN/MMP3/MMP9/MMP19/FAP/DDR2/CLASP1/A2M/PRSS2	18
BP	GO:1904377	positive regulation of protein localization to cell periphery	15/2486	63/18670	0.01653	0.1004	0.0787	PDPK1/CLIP3/SQSTM1/TNF/DLG1/EGFR/STAC/ITGA3/STAC2/RAMP3/STX4/SORBS1/TREM2/ARHGEF16/EPHB2	15
BP	GO:0042481	regulation of odontogenesis	8/2486	26/18670	0.01655	0.1004	0.0787	BCOR/CSF1/TGFB1/BMP2/DMRT3/CD34/ASPN/MSX1	8
BP	GO:0051125	regulation of actin nucleation	8/2486	26/18670	0.01655	0.1004	0.0787	ARF1/AP1AR/WHAMM/WASF1/FCHSD2/NCKAP1/CORO1A/MAGEL2	8
BP	GO:0032330	regulation of chondrocyte differentiation	13/2486	52/18670	0.01664	0.1007	0.07896	MAF/FGF18/RELA/WNT9A/SOX9/SHOX2/GLI3/HOXA11/EFEMP1/PKDCC/SIX2/ADAMTS12/SOX6	13
BP	GO:1990089	response to nerve growth factor	13/2486	52/18670	0.01664	0.1007	0.07896	NTF3/PDPK1/BDNF/CREB1/NTRK2/PTN/CBL/WASF1/MAGI2/ACAP2/HSPA5/CDC5L/CORO1A	13
BP	GO:0006401	RNA catabolic process	68/2486	397/18670	0.01668	0.1009	0.07909	RPS27/PSMD14/PSMD12/RPS28/LSM4/PABPC4/PELO/PNRC2/CNOT8/CNOT4/YTHDF2/PPP2CA/FXR1/DHX9/PSMD7/DEDD2/HNRNPM/PSMB5/RPS15/LSM7/TNRC6B/ZFP36/UBA52/ERN1/RPS26/LARP1/RPLP1/RPL28/RPS3A/DCP2/ZC3H12A/MTPAP/RPL10/EXOSC3/HSPB1/RNASE3/RPL29/POLR2G/YWHAZ/RPS8/RPS4Y1/RPS2/RPL39/RPS10/NUP214/RNASEH1/PSMB7/YBX1/RPL6/PSMD1/BTG2/PSMD9/UBC/SMG6/YTHDF3/CNOT7/RPL14/RPS7/MTOR/SET/TNKS1BP1/PSME1/POLR2D/RC3H1/RPL9/RPL15/DDX6/CNOT1	68
BP	GO:0016202	regulation of striated muscle tissue development	30/2486	152/18670	0.0167	0.1009	0.07909	SIRT2/YY1/MAPK11/TBX5/TWIST1/AKIRIN1/TGFB1/CREB1/CYP26B1/BMP2/LOX/IGF1/SIX1/MIR17HG/NR1D2/EFNB2/CDON/FRS2/MTM1/TBX2/NOTCH1/SHOX2/YAP1/JARID2/GPC1/ZFPM2/TBX1/MTOR/SOX6/PIN1	30
BP	GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II	9/2486	31/18670	0.01673	0.101	0.07916	JUN/TGFB2/TGFB1/SMAD1/BMP2/FOS/RELA/KLF5/NR3C1	9
BP	GO:0002224	toll-like receptor signaling pathway	29/2486	146/18670	0.01693	0.102	0.07995	PDPK1/TNFAIP3/OTUD4/FADD/NFKBIA/HSP90B1/IRF1/BCL10/LTF/LILRA4/UBA52/TNIP1/IRF4/BTK/TRAF6/MAP3K1/RAB7B/CNPY3/CD300LF/UBC/UBE2D3/COLEC12/TLR9/CD300A/CAV1/LYN/TRIL/NR1H4/RSAD2	29
BP	GO:0051384	response to glucocorticoid	29/2486	146/18670	0.01693	0.102	0.07995	ANXA3/FOSB/SPARC/ARG1/TNF/CDO1/TGFB1/IGFBP2/TRH/ZFP36/AKAP13/CCND1/PAM/ALPL/FOS/EGFR/HSD11B2/STC1/ASS1/CPN1/AQP1/CPS1/NR3C1/REST/FAM107A/DUSP1/SLIT2/ADCYAP1/FIBIN	29
BP	GO:0035710	CD4-positive, alpha-beta T cell activation	20/2486	92/18670	0.0172	0.1036	0.08118	ARG2/SMAD7/CD83/TWSG1/MIR21/ZC3H12A/IRF4/NFKBIZ/HLX/PTGER4/IL23R/BATF/CDH26/IL12A/TMEM98/IL2/MTOR/SPN/RC3H1/RSAD2	20
BP	GO:0043901	negative regulation of multi-organism process	33/2486	171/18670	0.01725	0.1038	0.08133	SIRT2/SLPI/TNFAIP3/ARG2/HTRA1/TRIM6/EIF2AK4/TNF/JUN/LTF/IFITM3/PRDX2/TRIM21/ZFP36/IFI16/ITCH/TNIP1/SRPK2/GPATCH3/ZC3H12A/ILF3/PML/IGF1/TSPAN6/IFIT1/IFIT5/IFITM2/RNF125/REST/CCL8/HPGDS/PCBP2/RSAD2	33
BP	GO:0018210	peptidyl-threonine modification	27/2486	134/18670	0.01731	0.104	0.08152	SIRT2/SPRY2/CHI3L1/ACVR1/CIT/PDPK1/TRIM6/PARD3/PRKCB/CLK1/SMAD7/GALNT3/TGFB1/CDC42BPA/HIPK1/PPEF2/EGF/CSNK1A1/TTBK2/PLK1/PRKAG2/CDK5R1/WNT5A/TTK/MTOR/TNKS1BP1/TAF1	27
BP	GO:0051865	protein autoubiquitination	16/2486	69/18670	0.01739	0.1043	0.08174	CNOT4/TRIM58/TRIM21/ITCH/RNF213/RNF183/TRAF6/UBE4B/MTA1/LRSAM1/DTX3L/UBE2D3/RNF19B/TAF1/RNF220/RNF8	16
BP	GO:0086003	cardiac muscle cell contraction	16/2486	69/18670	0.01739	0.1043	0.08174	SRI/SCN1B/DLG1/GJA5/PDE4B/SGCD/JUP/KCND3/STC1/KCNA5/NUP155/KCNJ8/ANK2/FLNA/RYR2/CAV1	16
BP	GO:0048024	regulation of mRNA splicing, via spliceosome	21/2486	98/18670	0.01742	0.1043	0.08174	TRA2B/RBM4/MBNL1/WTAP/YTHDC1/RBM7/SRPK2/SF3B4/RBM3/ZBTB7A/RBMXL1/JMJD6/TRA2A/HNRNPK/CELF1/ZC3H10/KHDRBS1/KHDRBS3/REST/RBMX/MBNL2	21
BP	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	21/2486	98/18670	0.01742	0.1043	0.08174	CLU/MUC1/NOL3/DNAJA1/PINK1/HYOU1/HERPUD1/MIR21/BDKRB2/SIRT1/BCL2L1/NME5/HSPB1/SFRP2/CXCL12/MMP9/MCL1/CREB3L1/NONO/TRIAP1/WFS1	21
BP	GO:0032606	type I interferon production	26/2486	128/18670	0.01745	0.1044	0.08181	TNFAIP3/XRCC6/YY1/EP300/NFKB2/IRF1/LILRA4/DHX9/TRIM21/IFI16/ITCH/GPATCH3/MIR21/CREBBP/REL/PQBP1/IFIH1/CYLD/RELA/RNF216/RNF125/TLR9/PCBP2/SETD2/PIN1/ZCCHC3	26
BP	GO:0071887	leukocyte apoptotic process	22/2486	104/18670	0.01756	0.1047	0.08206	ARG2/FADD/BCL10/CRKL/GAS6/BTK/SIRT1/P2RX7/CXCL12/MIR17HG/IRS2/PIK3CD/IL2/GLI3/CCL21/WNT5A/HCLS1/LYN/BAK1/TSC22D3/DOCK8/AXL	22
BP	GO:0098732	macromolecule deacylation	22/2486	104/18670	0.01756	0.1047	0.08206	SIRT2/RBM14/BEX4/EP300/AKAP8L/NIPBL/SFPQ/TGFB1/PINK1/BRMS1L/LYPLAL1/SIRT1/MTA1/MORF4L2/PRDM5/REST/SUDS3/SIRT7/AKAP8/SIN3B/PER1/SIN3A	22
BP	GO:1903578	regulation of ATP metabolic process	25/2486	122/18670	0.01756	0.1047	0.08206	SLC25A33/SNCA/NUP93/PINK1/PFKFB2/FLCN/ZBTB7A/NUP50/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/VCP/RAE1/NUP188/COX7A1/NUP160/NUP54/NUP214/NUP155/NUPR1/SLC2A6/PRKAG2/TREM2	25
BP	GO:0007093	mitotic cell cycle checkpoint	32/2486	165/18670	0.01758	0.1047	0.08209	MUC1/CRADD/CNOT8/CNOT4/EP300/RPS27L/SYF2/APC/DLG1/TGFB1/CCND1/MIR21/MDM4/BCL2L1/PML/FOXN3/BUB1B/WNT9A/PLK3/PLK1/BTG2/CDKN2B/CHFR/DUSP1/CNOT7/TTK/TRIAP1/TNKS1BP1/E2F8/MUS81/CNOT1/ZNF830	32
BP	GO:0070252	actin-mediated cell contraction	24/2486	116/18670	0.01762	0.1048	0.08217	SRI/SCN1B/TMOD1/MYL6B/MYL4/DLG1/TPM1/GJA5/PDE4B/SGCD/JUP/KCND3/STC1/PDPN/KCNA5/NUP155/EMP2/KCNJ8/ANK2/FLNA/RYR2/CAV1/DMD/PARVA	24
BP	GO:0002832	negative regulation of response to biotic stimulus	12/2486	47/18670	0.01781	0.1058	0.0829	SIRT2/TNFAIP3/ARG2/HTRA1/LTF/PRDX2/ITCH/GPATCH3/TSPAN6/CEACAM1/RNF125/PCBP2	12
BP	GO:1903115	regulation of actin filament-based movement	12/2486	47/18670	0.01781	0.1058	0.0829	SRI/FGF13/DLG1/GJA5/PDE4B/JUP/STC1/PDPN/ANK2/FLNA/RYR2/CAV1	12
BP	GO:0044706	multi-multicellular organism process	41/2486	222/18670	0.01789	0.1062	0.08323	ARID1A/PLA2G4C/FOSB/ARG1/HPGD/ADCY7/GHRL/TGFB1/STOX2/IGFBP2/FKBP4/MIR21/PAM/COL16A1/FOS/SPP1/SP3/HSD11B2/STC1/ACVR2A/RPL29/ADIPOR2/ITGA3/PTN/PTGFR/RAMP2/MMP9/NR2F2/IGFBP5/EMP2/IL1B/ANGPT2/OXTR/FBLN1/BYSL/STC2/MTOR/ADCYAP1/ITGA2/KLF1/JUNB	41
BP	GO:0042093	T-helper cell differentiation	14/2486	58/18670	0.01795	0.1064	0.08342	SMAD7/MIR21/ZC3H12A/IRF4/NFKBIZ/HLX/PTGER4/IL23R/BATF/TMEM98/IL2/MTOR/SPN/RC3H1	14
BP	GO:0150076	neuroinflammatory response	17/2486	75/18670	0.01808	0.1071	0.08391	CLU/C1QA/MMP8/SNCA/TNF/JUN/CX3CL1/EGFR/IGF1/MMP3/MMP9/SMO/NUPR1/IL1B/IL33/TREM2/PTPRC	17
BP	GO:0009755	hormone-mediated signaling pathway	43/2486	235/18670	0.01815	0.1074	0.08417	RBM14/ARID1A/GRIP1/NCOA3/ASIP/FHL2/PPARG/EP300/HEYL/RNF6/KDM5D/DNAJA1/GHRL/SAFB2/FKBP4/PHB2/RXRB/TRH/KANK2/AKAP13/THRB/ZBTB7A/DAB2/SIRT1/ADIPOR2/DDX54/TGFB1I1/NR2F2/NR1D2/YAP1/NR2F6/SFRP1/RXFP2/SKP2/NR3C1/NR4A2/TAF1/PER1/NCOA6/NR1H4/CNOT1/NR5A2/NCOA1	43
BP	GO:0034250	positive regulation of cellular amide metabolic process	30/2486	153/18670	0.0182	0.1075	0.08425	CLU/PPP1R15A/EIF5A/RPS27L/EIF2AK4/TNF/YTHDF2/FXR1/DHX9/PINK1/SERP1/RBM3/LARP1/SMPD3/YTHDF1/POLR2G/PLK3/PRR16/KHDRBS1/MIF4GD/YTHDF3/RMND1/PCIF1/RBMS3/MTOR/ITGA2/CDC123/UHMK1/POLR2D/LARP6	30
BP	GO:0050729	positive regulation of inflammatory response	30/2486	153/18670	0.0182	0.1075	0.08425	SUCNR1/MMP8/NFKBIA/SNCA/TNF/LPL/DHX9/PDE2A/TNIP1/CX3CL1/MIR21/NFKBIZ/BTK/PTGER4/EGFR/NEAT1/TNFRSF11A/AGTR1/OSMR/IL2/NUPR1/IL1B/PLA2G2A/IL17D/IL33/TREM2/WNT5A/TLR9/ITGA2/CCL18	30
BP	GO:0042180	cellular ketone metabolic process	45/2486	248/18670	0.01833	0.1081	0.08475	PSMD14/PSMD12/PPTC7/PDPR/CYP11A1/PPARG/DHRS9/SNCA/TWIST1/FABP5/PSMD7/PSMB5/CYP4F2/ERLIN1/COQ10B/MIR21/BMP2/APOC1/SIRT1/ERLIN2/ADIPOR2/CEACAM1/AKR1C2/IRS2/CBR3/PDP1/PSMB7/AADAT/PRKAG2/IL1B/PSMD1/PSMD9/REST/WDTC1/AZIN1/CAV1/HSD17B3/MTOR/PSME1/PDK4/DKK3/NR1H4/FABP3/ELOVL5/NQO1	45
BP	GO:0002262	myeloid cell homeostasis	29/2486	147/18670	0.01848	0.1083	0.08489	ALAS2/KLF13/SH2B3/EPB42/INPP5D/SLC4A1/INHBA/GATA1/L3MBTL3/TRIM58/IREB2/TAL1/LDB1/AHSP/ZFP36/ARID4A/ZBTB7A/PDE4B/SP3/ACVR2A/JMJD6/PIK3CD/HCLS1/LYN/BAK1/KLF1/SOX6/AXL/HSPA9	29
BP	GO:0006474	N-terminal protein amino acid acetylation	6/2486	17/18670	0.01851	0.1083	0.08489	EP300/NAA16/NAA30/CREBBP/NAA25/NAA15	6
BP	GO:0010715	regulation of extracellular matrix disassembly	6/2486	17/18670	0.01851	0.1083	0.08489	TGFB1/CLASP2/PDPN/FAP/DDR2/CLASP1	6
BP	GO:0035313	wound healing, spreading of epidermal cells	6/2486	17/18670	0.01851	0.1083	0.08489	CLASP2/PHLDB2/COL5A1/RREB1/MTOR/CLASP1	6
BP	GO:0035729	cellular response to hepatocyte growth factor stimulus	6/2486	17/18670	0.01851	0.1083	0.08489	SIRT2/CREB1/NRP1/RELA/BCAR1/ADAMTS12	6
BP	GO:0072673	lamellipodium morphogenesis	6/2486	17/18670	0.01851	0.1083	0.08489	WASF2/ARHGEF7/PDPN/WASF1/ENPP2/RREB1	6
BP	GO:0099010	modification of postsynaptic structure	6/2486	17/18670	0.01851	0.1083	0.08489	WASF3/CTTNBP2/WASF1/MYH10/PFN1/STAU1	6
BP	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell	6/2486	17/18670	0.01851	0.1083	0.08489	ITGA4/TNF/ELANE/MIR21/TRAF6/RELA	6
BP	GO:2000811	negative regulation of anoikis	6/2486	17/18670	0.01851	0.1083	0.08489	NTRK2/CEACAM6/MCL1/NOTCH1/CAV1/PDK4	6
BP	GO:0030811	regulation of nucleotide catabolic process	18/2486	81/18670	0.0186	0.1087	0.08521	NUP93/PFKFB2/ZBTB7A/NUP50/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/RAE1/NUP188/NUP160/NUP54/NUP214/NUP155/NUPR1/SLC2A6/PRKAG2	18
BP	GO:0010594	regulation of endothelial cell migration	42/2486	229/18670	0.01866	0.109	0.08542	ITGB3/ANXA3/PDPK1/PPARG/SPARC/VEGFC/TGFB1/NRP1/FBXW7/MIR21/ZC3H12A/FGF18/MMRN2/SIRT1/JUP/NOS3/HSPB1/STC1/SMOC2/ADAMTS9/CARD10/VASH1/PTN/RHOJ/CEACAM1/NR2F2/DNAJA4/SRPX2/MEOX2/BCAR1/KLF4/EMP2/NOTCH1/TEK/ANGPT2/PDCD10/WNT5A/DCN/MAP3K3/SLIT2/KDR/CCBE1	42
BP	GO:0030178	negative regulation of Wnt signaling pathway	39/2486	210/18670	0.01887	0.11	0.0862	GRB10/PSMD14/PSMD12/SLC9A3R1/PTPRO/APC/WNT5B/PSMD7/PSMB5/IGFBP2/NXN/BMP2/NFATC4/DAB2/RNF213/DDIT3/WWTR1/CYLD/SFRP2/CSNK1A1/IGFBP4/STK4/SFRP4/PSMB7/SOX9/NOTCH1/TSKU/GLI3/CTHRC1/PSMD1/SFRP1/PSMD9/WNT5A/ALPK2/CAV1/RBMS3/PSME1/DKK3/LZTS2	39
BP	GO:0043523	regulation of neuron apoptotic process	39/2486	210/18670	0.01887	0.11	0.0862	NTF3/PDPK1/FAIM2/BDNF/SNCA/TNF/JUN/TGFB2/PINK1/HYOU1/NRP1/CRLF1/SRPK2/FBXW7/STXBP1/CX3CL1/NFATC4/DDIT3/BCL2L1/NTRK2/SIX1/POU4F1/TRIM2/MCL1/NUPR1/BTG2/NES/CDK5R1/PAK3/NONO/NR4A2/HSP90AB1/SET/WFS1/CORO1A/AXL/NQO1/KIF14/PIN1	39
BP	GO:0001935	endothelial cell proliferation	36/2486	191/18670	0.0189	0.1101	0.08626	ITGB3/PDPK1/PPARG/ITGA4/SPARC/ARG1/CAV2/TNF/FLT1/JUN/DLG1/GHRL/VEGFC/NRP1/ERN1/MIR21/BMP2/EGFL7/SIRT1/THBS4/ECM1/CXCL12/VASH1/NR2F2/AGTR1/SULF1/APLNR/CD34/TEK/ALDH1A2/PDCD10/WNT5A/CAV1/MTOR/KDR/THAP1	36
BP	GO:1903322	positive regulation of protein modification by small protein conjugation or removal	27/2486	135/18670	0.01897	0.1103	0.08644	PEF1/SMAD7/BCL10/PINK1/CDK9/TNIP1/RASSF5/FBXW7/ZC3H12A/FBXO4/TRAF6/UBE2S/DERL1/MTA1/VCP/RPS2/RCHY1/PLK1/UBE2C/SKP2/FAM107A/CHFR/CAV1/WFS1/HSPA5/MYCBP2/PIN1	27
BP	GO:0046579	positive regulation of Ras protein signal transduction	15/2486	64/18670	0.01901	0.1103	0.08644	CSF1/CRKL/LPAR6/AKAP13/GPR4/VAV1/LPAR4/GPR35/IGF1/IRS2/PDGFRB/NOTCH1/NOTCH2/P2RY8/LYN	15
BP	GO:0050922	negative regulation of chemotaxis	15/2486	64/18670	0.01901	0.1103	0.08644	PTPRO/SEMA3B/PLXNA3/ELANE/SEMA3G/NRP1/SEMA4D/SEMA6D/SEMA5B/NOTCH1/ANGPT2/WNT5A/DUSP1/SLIT2/SEMA3E	15
BP	GO:0060135	maternal process involved in female pregnancy	15/2486	64/18670	0.01901	0.1103	0.08644	ARG1/ADCY7/GHRL/STOX2/PAM/SPP1/STC1/ITGA3/PTN/NR2F2/ANGPT2/STC2/MTOR/KLF1/JUNB	15
BP	GO:0031334	positive regulation of protein complex assembly	48/2486	268/18670	0.01906	0.1105	0.08659	CLU/RHOBTB1/CTTN/PMAIP1/BCLAF1/BAG4/NAV3/ARF1/TNF/TWIST1/JUN/DLG1/MMP1/TGFB1/PINK1/TAL1/CREB1/GTF2H3/HSP90AA1/P2RY12/G3BP2/MSN/VCP/AP1AR/MMP3/NIN/LMOD1/BMF/WHAMM/WASF1/IDE/MYO1C/FCHSD2/CCL21/MPP7/CDK5R1/NCKAP1/ARPC2/CDH5/MTOR/CLASP1/TAF1/PFN1/UNC13B/CDC42EP5/CORO1A/MAGEL2/CNOT1	48
BP	GO:0045444	fat cell differentiation	41/2486	223/18670	0.01919	0.1111	0.08708	SIRT2/PPARG/EP300/CLIP3/NIPBL/TNF/DUSP10/LPL/WNT5B/TGFB1/CREB1/ZFP36/HES1/CCND1/MIR21/ZC3H12A/BMP2/ZBTB7A/SIRT1/DDIT3/WWTR1/RARRES2/SFRP2/GNB3/ARL4A/PLCB1/CCDC3/STK4/TGFB1I1/KLF4/BSCL2/KLF5/WDFY2/SFRP1/ZFPM2/WNT5A/RUNX1T1/NR4A2/EBF2/MTOR/LRP5	41
BP	GO:1903708	positive regulation of hemopoiesis	35/2486	185/18670	0.01935	0.1119	0.08774	INPP5D/FADD/INHBA/PPP2R3C/GATA1/CSF1/TNF/JUN/DUSP10/TRIM58/TGFB1/TAL1/CREB1/GAS6/CD83/MIR21/FOXC1/NFKBIZ/HLX/FOS/BTK/TRAF6/IL23R/CYLD/ACVR2A/KLF10/IL12A/IL2/POU4F1/RAB7B/GLI3/TREM2/HCLS1/PTPRC/AXL	35
BP	GO:0048525	negative regulation of viral process	21/2486	99/18670	0.01942	0.1121	0.08788	SLPI/TRIM6/EIF2AK4/TNF/JUN/LTF/IFITM3/TRIM21/ZFP36/IFI16/TNIP1/SRPK2/ZC3H12A/ILF3/PML/IFIT1/IFIT5/IFITM2/REST/CCL8/RSAD2	21
BP	GO:0031398	positive regulation of protein ubiquitination	24/2486	117/18670	0.01945	0.1121	0.08788	PEF1/SMAD7/BCL10/PINK1/CDK9/RASSF5/FBXW7/FBXO4/TRAF6/UBE2S/DERL1/MTA1/RPS2/RCHY1/PLK1/UBE2C/SKP2/FAM107A/CHFR/CAV1/WFS1/HSPA5/MYCBP2/PIN1	24
BP	GO:0007519	skeletal muscle tissue development	31/2486	160/18670	0.01945	0.1121	0.08788	MEF2D/EP300/HEYL/MYL6B/CAV2/TWIST1/AKIRIN1/TGFB1/CYP26B1/HLX/FOS/ELN/CCNT2/SIX1/HLF/NR2F2/NR1D2/CDON/SMO/MEOX2/MTM1/NUPR1/KLF5/NOTCH1/SHOX2/BTG2/GPC1/DCN/TBX1/CAV1/HOXD9	31
BP	GO:0046661	male sex differentiation	31/2486	160/18670	0.01945	0.1121	0.08788	MAMLD1/INHBA/GATA1/RAB13/TGFB2/CRKL/SAFB2/FKBP4/ARID4A/CCND1/BCL2L1/SFRP2/DMRT3/ACVR2A/PDGFRA/CBL/HOXA10/PDGFRB/NUPR1/SOX9/HOXA11/SFRP1/RXFP2/ZFPM2/NUP210L/WNT5A/FLNA/HMGCS1/HSD17B3/HOXA9/NCOA1	31
BP	GO:0002708	positive regulation of lymphocyte mediated immunity	22/2486	105/18670	0.0195	0.1123	0.08802	FAM49B/CD1C/FADD/TNF/IL1R1/TGFB1/FBXO38/CD1B/BTK/EXOSC3/TRAF6/IL23R/VAV1/P2RX7/HLA-B/IL12A/IL2/IL1B/FZD5/PTPRC/RSAD2/HLA-A	22
BP	GO:0036294	cellular response to decreased oxygen levels	40/2486	217/18670	0.01972	0.1135	0.08892	SIRT2/PSMD14/PMAIP1/PSMD12/DDAH1/EP300/TWIST1/NOL3/PSMD7/PINK1/PSMB5/PHB2/HYOU1/UBA52/CACNB3/MIR21/CREBBP/SIRT1/MDM4/STC1/TBL2/CHCHD2/PTN/CBL/PLK3/AQP1/PSMB7/CPEB1/KCNK3/CD34/NOTCH1/PSMD1/SFRP1/PSMD9/UBC/MIR214/STC2/MTOR/PSME1/CPEB2	40
BP	GO:0031099	regeneration	37/2486	198/18670	0.01986	0.1138	0.08918	ANXA3/PPARG/RGMA/CD9/JUN/DUSP10/AKIRIN1/TGFB1/RTN4RL1/PTGFRN/GAS6/CCND1/STK24/SPP1/EGFR/NNMT/IGF1/CXCL12/PTN/PTPRF/LRIG2/PRRX1/KLF4/GAP43/KLF5/NOTCH1/YAP1/GLI3/MATN2/FKBP1B/THY1/ANGPT2/INPP5F/POSTN/BAK1/TNC/AXL	37
BP	GO:0003156	regulation of animal organ formation	10/2486	37/18670	0.01989	0.1138	0.08918	TBX5/SPRY1/HES1/BMP2/SIX1/SULF1/FRS2/NOTCH1/HOXA11/WNT5A	10
BP	GO:0007431	salivary gland development	10/2486	37/18670	0.01989	0.1138	0.08918	POLB/TNF/TGFB2/TGFB1/NRP1/TWSG1/NFIB/EGFR/PLXNA1/NTN4	10
BP	GO:0030212	hyaluronan metabolic process	10/2486	37/18670	0.01989	0.1138	0.08918	TGFB1/SMPD3/EGF/HAS2/IL1B/LYVE1/HAS3/HAS1/ITIH2/HYAL1	10
BP	GO:0043029	T cell homeostasis	10/2486	37/18670	0.01989	0.1138	0.08918	PMAIP1/FADD/PPP2R3C/TGFB1/P2RX7/IL2/PPP3CB/TSC22D3/RC3H1/CORO1A	10
BP	GO:2000273	positive regulation of signaling receptor activity	10/2486	37/18670	0.01989	0.1138	0.08918	NCOA3/PINK1/TAL1/FBXW7/ADRA2A/EGF/TAF1/ARC/EPHB2/SHANK3	10
BP	GO:0051668	localization within membrane	29/2486	148/18670	0.02015	0.1152	0.09028	ITGB3/GRIP1/ITGA4/DLG1/CRKL/TGFB1/SSH1/AGRN/DLG2/GRIP2/GPC4/WDR19/PIGR/PTN/GPC6/ITGAL/GRASP/EFNB2/SEC24B/DNM1/THY1/FLNA/MAGI2/SSNA1/ARC/GLRB/RAB8A/PTPRC/SHANK3	29
BP	GO:0003018	vascular process in circulatory system	33/2486	173/18670	0.02024	0.1155	0.09051	HBB/DDAH1/EDNRB/TGFB1/PTP4A3/PDE2A/ACE/ADRA2A/GJA5/MIR21/FOXC1/GRIP2/BDKRB2/EDN3/GCH1/EGFR/NOS3/ADCY6/RAMP2/CEACAM1/P2RY2/KCNA5/AGTR1/HRH1/KCNMA1/TEK/CPS1/OXTR/CDH5/CAV1/SLIT2/ADCYAP1/ACTA2	33
BP	GO:0036119	response to platelet-derived growth factor	7/2486	22/18670	0.02031	0.1155	0.09051	CREB1/PTN/CBL/PDGFRB/HAS2/HAS1/HYAL1	7
BP	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	7/2486	22/18670	0.02031	0.1155	0.09051	SPRY2/SPRY1/SPRY4/SULF1/CREB3L1/GPC1/WNT5A	7
BP	GO:0045117	azole transport	7/2486	22/18670	0.02031	0.1155	0.09051	SLC15A4/SLC35F3/BTK/SNAP23/LYN/ADCYAP1/SLC25A29	7
BP	GO:0060065	uterus development	7/2486	22/18670	0.02031	0.1155	0.09051	NIPBL/TGFB2/CDKN1C/HOXA10/HOXA11/WNT5A/HOXA9	7
BP	GO:0060390	regulation of SMAD protein signal transduction	7/2486	22/18670	0.02031	0.1155	0.09051	VEPH1/NUP93/TGFB1/DAB2/WWTR1/RBPMS/CILP	7
BP	GO:0043112	receptor metabolic process	36/2486	192/18670	0.02037	0.1157	0.09067	ITGB3/MYLIP/NTF3/PPARG/ARF1/CD9/SNCA/ANKRD13D/ARFGEF2/TNF/TGFB1/SORL1/PLEKHJ1/ITCH/ANKRD13B/CXCR1/CALCRL/AP2A2/ANKRD13A/EGF/AP1AR/RAMP2/HNRNPK/CEACAM1/TBC1D16/SFRP4/EFNB2/RAMP3/DNM1/DTX3L/CAMLG/UVRAG/MAGI2/CAV1/INPP5F/ARC	36
BP	GO:0048844	artery morphogenesis	17/2486	76/18670	0.02048	0.1162	0.09109	HPGD/SMAD7/TGFB2/HES1/NRP1/GJA5/FOXC1/ADAMTS9/SIX1/EFNB2/SEC24B/PRRX1/PDGFRB/TBX2/NOTCH1/TBX1/NOTCH3	17
BP	GO:0042573	retinoic acid metabolic process	9/2486	32/18670	0.02059	0.1164	0.09126	DHRS9/CYP26B1/CRABP1/CYP27C1/ALDH1A3/ALDH1A2/CYP3A5/RBP1/ADH1C	9
BP	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	9/2486	32/18670	0.02059	0.1164	0.09126	FLT1/TGFB1/P2RY12/PDGFRA/PDGFRB/TEK/CCL21/VAV3/LYN	9
BP	GO:0061311	cell surface receptor signaling pathway involved in heart development	9/2486	32/18670	0.02059	0.1164	0.09126	ACVR1/HEYL/TGFB1/BMP2/NOTCH1/NOTCH2/WNT5A/MSX1/ALPK2	9
BP	GO:0071295	cellular response to vitamin	9/2486	32/18670	0.02059	0.1164	0.09126	PPARG/KANK2/GAS6/PHEX/TRIM24/PTN/SFRP1/POSTN/TNC	9
BP	GO:0035051	cardiocyte differentiation	32/2486	167/18670	0.02068	0.1165	0.09131	ARID1A/ACVR1/YY1/TBX5/TWIST1/TGFB2/TGFB1/SPRY1/KDM6B/HES1/AKAP13/MIR21/BMP2/SGCD/EGFR/OBSL1/IGF1/PDGFRA/ALPK3/EFNB2/FRS2/PDGFRB/TBX2/NOTCH1/REST/NOX4/SGCB/ALPK2/MTOR/MYH10/SOX6/PIN1	32
BP	GO:0001658	branching involved in ureteric bud morphogenesis	14/2486	59/18670	0.02074	0.1165	0.09131	PBX1/DLG1/TGFB1/BMP2/NPNT/SIX1/HOXB7/SMO/SOX9/GLI3/HOXA11/ADAMTS16/SIX2/GZF1	14
BP	GO:0045824	negative regulation of innate immune response	14/2486	59/18670	0.02074	0.1165	0.09131	TNFAIP3/PPARG/ARG1/YTHDF2/DUSP10/IFI16/SAMHD1/MIR21/SERPING1/CEACAM1/SERPINB9/YTHDF3/CNOT7/A2M	14
BP	GO:0048193	Golgi vesicle transport	63/2486	368/18670	0.02078	0.1165	0.09131	PROS1/COG3/GOLGA5/GABARAPL2/TRAPPC10/SCFD1/VPS13C/PEF1/KIF26A/ARF1/PROC/CNIH3/ARFGEF2/CD59/CUX2/COPB2/GAS1/DYNC1I1/KLHL20/ACTR10/SORL1/HYOU1/GAS6/TFG/TMEM115/KIF4A/SEC16A/F8/VCP/BBS1/AP1AR/ANK1/BET1/LMAN1L/SLC10A7/SEC24B/WHAMM/STEAP2/RAB7B/KIF2C/CAPZA1/SNAP23/GOSR1/RAB12/STX4/RAB6B/KDELR3/ANK2/UVRAG/RNF139/ARFGAP2/SYS1/PKDCC/GOLGA3/BNIP1/DYNLL2/RAB8A/CCDC93/DCTN4/STXBP6/COPZ2/KLC1/NAPG	63
BP	GO:0071222	cellular response to lipopolysaccharide	38/2486	205/18670	0.02081	0.1165	0.09131	CXCL5/TNFAIP3/EDNRB/CTSG/NFKBIB/IRF8/ARG1/NFKBIA/TNF/BCL10/LTF/TGFB1/LCN2/PRDX2/ZFP36/CX3CL1/MIR21/ZC3H12A/PDE4B/CEBPE/TRAF6/NOS3/RELA/PLSCR4/ASS1/PABPN1/CXCL6/TFPI/PDCD1LG2/IL12A/IL1B/CXCL1/WNT5A/AKAP8/LYN/NR1H4/AXL/NLRP7	38
BP	GO:0015721	bile acid and bile salt transport	8/2486	27/18670	0.02084	0.1165	0.09131	SLC10A2/CEACAM1/SLC10A7/STARD5/NCOA2/SLCO2B1/NR1H4/NCOA1	8
BP	GO:0072378	blood coagulation, fibrin clot formation	8/2486	27/18670	0.02084	0.1165	0.09131	VWF/SERPING1/F8/F13A1/TFPI/FBLN1/GP1BA/A2M	8
BP	GO:0007528	neuromuscular junction development	12/2486	48/18670	0.02095	0.1165	0.09131	CACNA2D2/CRKL/AGRN/CACNB3/PTN/SIX1/COL4A1/UTRN/PDZRN3/UNC13B/TNC/SHANK3	12
BP	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	12/2486	48/18670	0.02095	0.1165	0.09131	ACVR1/INHBA/TGFB2/TGFB1/TWSG1/BMP2/DAB2/ACVR2A/INHBE/BMP8A/RBPMS/TTK	12
BP	GO:0035272	exocrine system development	12/2486	48/18670	0.02095	0.1165	0.09131	POLB/TNF/TGFB2/TGFB1/NRP1/TWSG1/FOXC1/NFIB/EGFR/SOX9/PLXNA1/NTN4	12
BP	GO:1903727	positive regulation of phospholipid metabolic process	12/2486	48/18670	0.02095	0.1165	0.09131	FLT1/TGFB1/P2RY12/PDGFRA/PDGFRB/TEK/CCL21/VAV3/DGKZ/LYN/NR1H4/FABP3	12
BP	GO:0051702	interaction with symbiont	18/2486	82/18670	0.02095	0.1165	0.09131	IFI27/STOM/CTSG/ARG1/EP300/EIF2AK4/CAV2/JUN/LTF/ELANE/CHD1/ZC3H12A/FN1/CAMP/CXCL6/AQP1/REST/CCL8	18
BP	GO:0035967	cellular response to topologically incorrect protein	31/2486	161/18670	0.02111	0.1165	0.09131	PPP1R15A/PPP1R15B/MBTPS1/EDEM1/EP300/SDF2L1/HSP90B1/KLHL15/SERP1/HYOU1/HERPUD1/EIF2S1/CCND1/ERN1/DNAJB14/SSR1/DDX11/DDIT3/TM7SF3/DERL1/TBL2/VCP/CREB3L1/KDELR3/STC2/BAK1/WFS1/HSPA5/SDF2/HSPB8/HSPA9	31
BP	GO:0001838	embryonic epithelial tube formation	25/2486	124/18670	0.02125	0.1165	0.09131	ARID1A/IRX2/TWIST1/BCL10/TGFB2/TGFB1/PHACTR4/LUZP1/IRX3/TRAF6/SFRP2/LIAS/SIX1/STK4/SEC24B/SOX9/CTHRC1/SFRP1/WNT5A/RPS7/DLC1/PFN1/SPINT2/SETD2/MTHFR	25
BP	GO:0010763	positive regulation of fibroblast migration	5/2486	13/18670	0.02126	0.1165	0.09131	BAG4/TGFB1/ARHGEF7/PAK3/DDR2	5
BP	GO:0015812	gamma-aminobutyric acid transport	5/2486	13/18670	0.02126	0.1165	0.09131	TRH/P2RX7/SLC32A1/SLC6A1/ABAT	5
BP	GO:0016322	neuron remodeling	5/2486	13/18670	0.02126	0.1165	0.09131	C1QA/BCL11A/CX3CL1/RND1/NTN4	5
BP	GO:0018206	peptidyl-methionine modification	5/2486	13/18670	0.02126	0.1165	0.09131	NAA16/NAA30/NAA25/METAP1/NAA15	5
BP	GO:0019627	urea metabolic process	5/2486	13/18670	0.02126	0.1165	0.09131	ARG2/ARG1/ASS1/CPS1/NR1H4	5
BP	GO:0031115	negative regulation of microtubule polymerization	5/2486	13/18670	0.02126	0.1165	0.09131	CLIP3/SNCA/FKBP4/MAP2/CDH5	5
BP	GO:0031650	regulation of heat generation	5/2486	13/18670	0.02126	0.1165	0.09131	EDNRB/TNF/TNFRSF11A/IL1B/ABAT	5
BP	GO:0033623	regulation of integrin activation	5/2486	13/18670	0.02126	0.1165	0.09131	FBLIM1/SELP/P2RY12/PTGER4/KIF14	5
BP	GO:0043116	negative regulation of vascular permeability	5/2486	13/18670	0.02126	0.1165	0.09131	DDAH1/PDE2A/RAMP2/CEACAM1/SLIT2	5
BP	GO:0046831	regulation of RNA export from nucleus	5/2486	13/18670	0.02126	0.1165	0.09131	AKAP8L/DHX9/NUP153/KHDRBS1/SETD2	5
BP	GO:0048681	negative regulation of axon regeneration	5/2486	13/18670	0.02126	0.1165	0.09131	RGMA/RTN4RL1/SPP1/LRIG2/INPP5F	5
BP	GO:0048715	negative regulation of oligodendrocyte differentiation	5/2486	13/18670	0.02126	0.1165	0.09131	DUSP10/DAAM2/HES1/TMEM98/NOTCH1	5
BP	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway	5/2486	13/18670	0.02126	0.1165	0.09131	SPRY2/NTF3/SPRY1/WASF1/DOK5	5
BP	GO:0061042	vascular wound healing	5/2486	13/18670	0.02126	0.1165	0.09131	TNFAIP3/SMOC2/ADIPOR2/CD34/MCAM	5
BP	GO:0070208	protein heterotrimerization	5/2486	13/18670	0.02126	0.1165	0.09131	COL6A1/NUP54/C1QTNF1/COL6A2/COL1A2	5
BP	GO:1901550	regulation of endothelial cell development	5/2486	13/18670	0.02126	0.1165	0.09131	CLDN5/PROC/TNF/IL1B/CDH5	5
BP	GO:1902430	negative regulation of amyloid-beta formation	5/2486	13/18670	0.02126	0.1165	0.09131	CLU/SORL1/IGF1/SPON1/PIN1	5
BP	GO:1902902	negative regulation of autophagosome assembly	5/2486	13/18670	0.02126	0.1165	0.09131	SCFD1/PINK1/SMCR8/MTM1/NUPR1	5
BP	GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding	5/2486	13/18670	0.02126	0.1165	0.09131	EP300/FBXW7/DDIT3/NSD1/TAF1	5
BP	GO:1903140	regulation of establishment of endothelial barrier	5/2486	13/18670	0.02126	0.1165	0.09131	CLDN5/PROC/TNF/IL1B/CDH5	5
BP	GO:2000052	positive regulation of non-canonical Wnt signaling pathway	5/2486	13/18670	0.02126	0.1165	0.09131	PLEKHA4/DAB2/RSPO3/SFRP1/WNT5A	5
BP	GO:2000177	regulation of neural precursor cell proliferation	19/2486	88/18670	0.02128	0.1165	0.09133	SIRT2/LIMS2/VEGFC/TGFB1/CX3CL1/EGF/PTN/NAP1L1/CDON/SMO/NOTCH1/GLI3/BTG2/NES/WNT5A/FLNA/LYN/ADCYAP1/SPINT2	19
BP	GO:1901796	regulation of signal transduction by p53 class mediator	34/2486	180/18670	0.02138	0.117	0.09166	MUC1/PHF20/PMAIP1/EP300/MAPK11/TAF4/TAF10/TWIST1/HIPK1/MIR21/TPX2/EXO1/BDKRB2/SIRT1/MDM4/TRIM24/PML/HNRNPK/TAF3/PLK3/BANP/POU4F1/PRKAG2/CDK5R1/MSX1/TP53BP2/CHD5/MAPKAPK5/RPS7/TRIAP1/TAF1/BARD1/PIN1/ING5	34
BP	GO:1990266	neutrophil migration	24/2486	118/18670	0.02142	0.1171	0.09177	CXCL5/CD177/TGFB2/IL1R1/CX3CL1/CXCR1/PDE4B/EDN3/THBS4/JAGN1/CCL13/VAV1/ITGA9/DAPK2/CXCL6/PIK3CD/IL1B/CCL21/CXCL1/VAV3/CCL8/SLIT2/CCL18/XG	24
BP	GO:0006906	vesicle fusion	20/2486	94/18670	0.02149	0.1172	0.09189	STX2/SNCA/CAV2/STX16/STX8/LRMP/TGFBRAP1/STXBP1/BET1/RAB7B/SNAP23/GOSR1/STX4/UVRAG/VAV3/SAMD9L/RAB8A/STXBP6/CORO1A/PRRT2	20
BP	GO:0060993	kidney morphogenesis	20/2486	94/18670	0.02149	0.1172	0.09189	IRX2/PBX1/DLG1/TGFB1/HES1/BMP2/IRX3/WWTR1/NPNT/SIX1/HOXB7/SMO/PDGFRB/SOX9/GLI3/HOXA11/ADAMTS16/SIX2/GZF1/LZTS2	20
BP	GO:0070498	interleukin-1-mediated signaling pathway	21/2486	100/18670	0.02159	0.1176	0.09216	PSMD14/PSMD12/OTUD4/NFKBIA/SQSTM1/IL1R1/PSMD7/PSMB5/UBA52/TRAF6/RELA/PLCB1/PSMB7/IL1B/PSMD1/PSMD9/UBC/MAP3K3/PSME1/RPS6KA5/CUL1	21
BP	GO:0090174	organelle membrane fusion	21/2486	100/18670	0.02159	0.1176	0.09216	STX2/SNCA/CAV2/STX16/STX8/LRMP/TGFBRAP1/STXBP1/BET1/RAB7B/SNAP23/GOSR1/STX4/UVRAG/VAV3/BNIP1/SAMD9L/RAB8A/STXBP6/CORO1A/PRRT2	21
BP	GO:0042136	neurotransmitter biosynthetic process	22/2486	106/18670	0.02161	0.1176	0.09216	CLU/HBB/DDAH1/MMP8/ARG2/DAGLB/TNF/SLC1A3/HSP90AA1/ZC3H12A/GCH1/NOS3/ASS1/KLF4/CD34/ACP5/IL1B/HSP90AB1/CAV1/MTOR/NQO1/ABAT	22
BP	GO:0071806	protein transmembrane transport	15/2486	65/18670	0.02176	0.1182	0.09264	CLU/SEC62/TIMM23/DNLZ/SEC61B/TOMM20/RTN2/TIMM44/TIMM10/TRAM1L1/GRPEL1/GPIHBP1/MCL1/HSPA5/SRP54	15
BP	GO:0072577	endothelial cell apoptotic process	15/2486	65/18670	0.02176	0.1182	0.09264	PDPK1/TNFAIP3/ITGA4/TNF/HIPK1/GAS6/ANGPTL4/COL18A1/ECSCR/MAP3K5/RAMP2/PAK4/TEK/CD248/KDR	15
BP	GO:0035690	cellular response to drug	63/2486	369/18670	0.02189	0.1188	0.09312	ADCY3/MAP1LC3A/TNFAIP3/RBM22/ARG1/BCL11A/HSP90B1/ADCY7/TNF/FXN/CRKL/TGFB1/SSH1/PINK1/AGRN/LCN2/KDM6B/PDE2A/GAS6/LARP1/MIR21/SMPD3/MT2A/P2RY12/ZC3H12A/PDE4B/PYCR1/DDX11/SIRT1/JUP/EGFR/ADCY6/P2RX7/MAP3K5/RELA/ASS1/PLCB1/MMP3/P2RY2/AQP1/KLF4/SOX9/CIB2/IL1B/SFRP1/PPP3CB/CDK5R1/NR3C1/PDCD10/REST/PPM1F/MSX1/RYR2/HSP90AB1/PCGF2/SLIT2/KDR/TAF1/HSPA5/SIN3A/AXL/NQO1/NCOA1	63
BP	GO:0045787	positive regulation of cell cycle	66/2486	389/18670	0.02192	0.1188	0.09314	MUC1/SIRT2/CRADD/CIT/CNOT8/CNOT4/EP300/NIPBL/RAB11FIP4/PBX1/SMC5/SFPQ/TGFB2/TGFB1/CDK9/TAL1/MTBP/PHB2/TRIM21/HES1/SRPK2/CCND1/SMPD3/DDX11/EDN3/MDM4/EGFR/MEIS2/PML/SMOC2/CCNT2/IGF1/EGF/CCNYL2/PLCB1/CDC45/DBF4/KCNA5/CCNY/PKP4/PLK3/POU4F1/PDGFRB/HCFC1/UBE2C/IL1B/BTG2/FAP/CRLF3/CDK5R1/PKN2/WNT5A/MIR214/MSX1/CNOT7/HSP90AB1/TRIAP1/TNKS1BP1/E2F8/GIPC1/ZNF268/LRP5/HYAL1/SIN3A/KIF14/CNOT1	66
BP	GO:0002706	regulation of lymphocyte mediated immunity	29/2486	149/18670	0.02193	0.1188	0.09314	FAM49B/CD1C/FADD/PARP3/ARG1/TNF/SMAD7/IL1R1/TGFB1/FBXO38/FCGR2B/CD1B/BTK/EXOSC3/TRAF6/IL23R/VAV1/P2RX7/HLA-B/CEACAM1/IL12A/IL2/SERPINB9/IL1B/PPP3CB/FZD5/PTPRC/RSAD2/HLA-A	29
BP	GO:0034614	cellular response to reactive oxygen species	32/2486	168/18670	0.02239	0.1212	0.09497	MAP1LC3A/TNFAIP3/ARG1/TNF/JUN/FXN/PINK1/TPM1/LCN2/PRDX2/KDM6B/MIR21/SMPD3/FOS/BTK/PYCR1/SIRT1/GCH1/EGFR/NOS3/MAP3K5/RELA/MMP3/PDGFRA/MMP9/AQP1/KLF4/PDCD10/PCGF2/SOD3/AXL/NQO1	32
BP	GO:0000413	protein peptidyl-prolyl isomerization	11/2486	43/18670	0.02245	0.1212	0.09499	PPIL6/PPIL1/FKBP4/PPID/FKBP10/NKTR/PPIC/FKBP1B/FKBP8/PIN4/PIN1	11
BP	GO:0045429	positive regulation of nitric oxide biosynthetic process	11/2486	43/18670	0.02245	0.1212	0.09499	CLU/HBB/DDAH1/MMP8/TNF/HSP90AA1/ASS1/KLF4/IL1B/HSP90AB1/MTOR	11
BP	GO:0086004	regulation of cardiac muscle cell contraction	11/2486	43/18670	0.02245	0.1212	0.09499	SRI/FGF13/DLG1/GJA5/PDE4B/JUP/STC1/ANK2/FLNA/RYR2/CAV1	11
BP	GO:0071479	cellular response to ionizing radiation	16/2486	71/18670	0.02254	0.1216	0.09531	XRCC6/POLE3/NIPBL/TGFB1/IFI16/FBXO4/SIRT1/BCL2L1/SFRP2/YAP1/SFRP1/NOX4/TNKS1BP1/HSPA5/MGMT/CRYAB	16
BP	GO:0002763	positive regulation of myeloid leukocyte differentiation	13/2486	54/18670	0.02257	0.1216	0.09533	FADD/CSF1/TNF/JUN/TGFB1/CREB1/FOS/TRAF6/IL23R/KLF10/POU4F1/TREM2/HCLS1	13
BP	GO:0015718	monocarboxylic acid transport	31/2486	162/18670	0.02288	0.1232	0.09657	LCN12/SLC9A3R1/PPARG/CPT1C/CYP4F2/TRH/PLA2G5/SLC10A2/ACE/BDKRB2/P2RX7/TNFRSF11A/CEACAM1/IRS2/SLC26A6/SLC10A7/SLC32A1/SLC16A4/PRKAG2/MFSD2A/IL1B/PLA2G2A/STARD5/SLCO2A1/NCOA2/SLCO2B1/NR1H4/FABP3/SLC6A1/ABAT/NCOA1	31
BP	GO:0051208	sequestering of calcium ion	26/2486	131/18670	0.02301	0.1238	0.09703	SRI/PDPK1/ITPR1/ATP7B/HSP90B1/SNCA/MCOLN3/NOL3/TGFB1/DIAPH1/CX3CL1/DDIT3/P2RX7/PLCB2/PLCB1/APLNR/IBTK/FKBP1B/CCL21/THY1/ANK2/RYR2/LYN/DMD/PTPRC/CORO1A	26
BP	GO:0051851	modification by host of symbiont morphology or physiology	17/2486	77/18670	0.02312	0.1243	0.09743	IFI27/STOM/CTSG/ARG1/EP300/EIF2AK4/CAV2/JUN/LTF/ELANE/CHD1/ZC3H12A/CAMP/CXCL6/AQP1/REST/CCL8	17
BP	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	25/2486	125/18670	0.0233	0.1252	0.0981	MUC1/CRADD/CNOT8/CNOT4/EP300/RPS27L/KANK2/CCND1/CTDSPL/CDKN2C/MIR21/MDM4/PML/CDK2AP2/PLK3/KLF4/BTG2/CDKN2B/GPNMB/FAM107A/CNOT7/TRIAP1/TNKS1BP1/E2F8/CNOT1	25
BP	GO:0048634	regulation of muscle organ development	30/2486	156/18670	0.02337	0.1254	0.09828	SIRT2/YY1/MAPK11/TBX5/TWIST1/AKIRIN1/TGFB1/CREB1/CYP26B1/BMP2/LOX/IGF1/SIX1/MIR17HG/NR1D2/EFNB2/CDON/FRS2/MTM1/TBX2/NOTCH1/SHOX2/YAP1/JARID2/GPC1/ZFPM2/TBX1/MTOR/SOX6/PIN1	30
BP	GO:0055074	calcium ion homeostasis	78/2486	471/18670	0.0235	0.126	0.09874	FAM20A/SRI/SLC24A3/PDPK1/ITPR1/EDNRB/GTF2I/ATP7B/PRKCB/HSP90B1/SNCA/MCOLN3/NOL3/SPPL3/GHRL/TGFB1/LPAR6/ELANE/HERPUD1/CACNB3/TACR1/DIAPH1/FAM155A/CX3CL1/CXCR1/BDKRB2/SGCD/GPR4/PTGER4/EDN3/DDIT3/CCL13/TRIM24/STC1/P2RX7/LPAR4/MCHR1/GPR35/PML/CXCL12/SLC24A5/PLCB2/SLC25A27/PTH1R/PTGFR/PLCB1/PDGFRA/KCNA5/AGTR1/C1QTNF1/IL2/RAMP3/APLNR/KCNK3/CIB2/IBTK/FKBP1B/CCL21/THY1/ANK2/SYPL2/OXTR/WNT5A/P2RY8/CCL8/RYR2/CDH5/CAV1/STC2/LYN/BAK1/C19orf12/ADCYAP1/DMD/WFS1/KL/PTPRC/CORO1A	78
BP	GO:0002223	stimulatory C-type lectin receptor signaling pathway	23/2486	113/18670	0.02375	0.1272	0.0997	MUC1/PSMD14/PSMD12/CLEC4C/PDPK1/EP300/BCL10/PSMD7/PSMB5/CREBBP/RAF1/TRAF6/RELA/PSMB7/PSMD1/MUC2/PSMD9/PAK3/LYN/MUC3A/PSME1/RPS6KA5/CUL1	23
BP	GO:0002294	CD4-positive, alpha-beta T cell differentiation involved in immune response	14/2486	60/18670	0.02383	0.1272	0.0997	SMAD7/MIR21/ZC3H12A/IRF4/NFKBIZ/HLX/PTGER4/IL23R/BATF/TMEM98/IL2/MTOR/SPN/RC3H1	14
BP	GO:0071774	response to fibroblast growth factor	29/2486	150/18670	0.02384	0.1272	0.0997	SPRY2/DSTYK/IER2/SNCA/GALNT3/CRKL/HNRNPM/SPRY1/ZFP36/FGF18/SPRY4/SMOC2/POLR2G/FLRT2/CBL/SULF1/FRS2/CREB3L1/CPS1/SFRP1/GPC1/WNT5A/TBX1/POSTN/KL/CDC5L/POLR2D/TNC/HYAL1	29
BP	GO:0046636	negative regulation of alpha-beta T cell activation	10/2486	38/18670	0.02386	0.1272	0.0997	ARG2/SMAD7/TWSG1/ZC3H12A/HLX/IL2/TNFRSF14/GLI3/CD300A/RC3H1	10
BP	GO:0046676	negative regulation of insulin secretion	10/2486	38/18670	0.02386	0.1272	0.0997	SYTL4/GHRL/ADRA2A/JAGN1/BMP8A/FKBP1B/SFRP1/PSMD9/REST/MIDN	10
BP	GO:0097064	ncRNA export from nucleus	10/2486	38/18670	0.02386	0.1272	0.0997	NUP93/NUP50/NUP153/NUP210/RAE1/NUP188/NUP160/NUP54/NUP214/NUP155	10
BP	GO:0001909	leukocyte mediated cytotoxicity	22/2486	107/18670	0.02389	0.1272	0.0997	FAM49B/CD1C/CTSG/FADD/ARG1/LYST/ELANE/FCGR2B/CD1B/IL23R/VAV1/P2RX7/CXCL6/HLA-B/CEACAM1/IL12A/SERPINB9/EMP2/PPP3CB/PTPRC/CORO1A/HLA-A	22
BP	GO:0048524	positive regulation of viral process	22/2486	107/18670	0.02389	0.1272	0.0997	STOM/EP300/CAV2/JUN/DHX9/CDK9/TRIM21/ADARB1/SRPK2/PPID/LARP1/CHD1/POLR2G/VPS37B/RSF1/IFIT1/NOTCH1/PKN2/CNOT7/POLR2D/STAU1/NR5A2	22
BP	GO:0071456	cellular response to hypoxia	38/2486	207/18670	0.02396	0.1275	0.0999	SIRT2/PSMD14/PMAIP1/PSMD12/DDAH1/EP300/TWIST1/NOL3/PSMD7/PINK1/PSMB5/PHB2/HYOU1/UBA52/MIR21/CREBBP/SIRT1/MDM4/STC1/TBL2/CHCHD2/PTN/PLK3/AQP1/PSMB7/CPEB1/KCNK3/CD34/NOTCH1/PSMD1/SFRP1/PSMD9/UBC/MIR214/STC2/MTOR/PSME1/CPEB2	38
BP	GO:0044843	cell cycle G1/S phase transition	52/2486	298/18670	0.02406	0.1278	0.1001	MUC1/IQGAP3/CRADD/ACVR1/PRIM2/CNOT8/CNOT4/POLE3/INHBA/EP300/RPS27L/TAF10/MTBP/PHB2/KANK2/FBXW7/CCND1/CTDSPL/CDKN2C/MIR21/POLE/MDM4/MAX/EGFR/PML/PLCB1/CDK2AP2/CDC45/DBF4/KCNA5/PLK3/KLF4/BTG2/CRLF3/KHDRBS1/CDKN2B/SKP2/GPNMB/MIR214/FAM107A/CNOT7/TRIAP1/TNKS1BP1/TAF1/E2F8/PSME1/CDKN3/HYAL1/KIF14/CNOT1/CUL1/MCM5	52
BP	GO:0090068	positive regulation of cell cycle process	52/2486	298/18670	0.02406	0.1278	0.1001	MUC1/SIRT2/CRADD/CIT/CNOT8/CNOT4/EP300/NIPBL/RAB11FIP4/PBX1/SMC5/SFPQ/TGFB1/MTBP/PHB2/CCND1/SMPD3/DDX11/EDN3/MDM4/EGFR/PML/IGF1/EGF/PLCB1/CDC45/DBF4/KCNA5/PKP4/PLK3/POU4F1/PDGFRB/UBE2C/IL1B/BTG2/FAP/CRLF3/CDK5R1/PKN2/WNT5A/MIR214/MSX1/CNOT7/TRIAP1/TNKS1BP1/E2F8/GIPC1/LRP5/HYAL1/SIN3A/KIF14/CNOT1	52
BP	GO:0060538	skeletal muscle organ development	32/2486	169/18670	0.0242	0.1284	0.1006	MEF2D/EP300/HEYL/MYL6B/CAV2/TWIST1/AKIRIN1/TGFB1/CYP26B1/HLX/FOS/ELN/CCNT2/ASS1/SIX1/HLF/NR2F2/NR1D2/CDON/SMO/MEOX2/MTM1/NUPR1/KLF5/NOTCH1/SHOX2/BTG2/GPC1/DCN/TBX1/CAV1/HOXD9	32
BP	GO:1902107	positive regulation of leukocyte differentiation	28/2486	144/18670	0.0243	0.1288	0.101	INPP5D/FADD/PPP2R3C/CSF1/TNF/JUN/DUSP10/TGFB1/CREB1/GAS6/CD83/MIR21/NFKBIZ/HLX/FOS/BTK/TRAF6/IL23R/CYLD/KLF10/IL12A/IL2/POU4F1/GLI3/TREM2/HCLS1/PTPRC/AXL	28
BP	GO:0008347	glial cell migration	12/2486	49/18670	0.02448	0.1294	0.1014	CSF1/TGFB2/CRKL/P2RY12/GLI3/MATN2/TREM2/LAMB1/CDK5R1/NDN/CSPG4/SUN2	12
BP	GO:0048546	digestive tract morphogenesis	12/2486	49/18670	0.02448	0.1294	0.1014	NIPBL/RBPMS2/HLX/EGFR/SFRP2/PDGFRA/NOTCH1/SHOX2/GLI3/SFRP1/WNT5A/SIX2	12
BP	GO:1904707	positive regulation of vascular smooth muscle cell proliferation	12/2486	49/18670	0.02448	0.1294	0.1014	MEF2D/HPGD/TNF/JUN/ERN1/MIR21/MAP3K5/IGF1/MMP9/IGFBP5/MIR214/FOXJ2	12
BP	GO:1990090	cellular response to nerve growth factor stimulus	12/2486	49/18670	0.02448	0.1294	0.1014	NTF3/PDPK1/BDNF/CREB1/NTRK2/CBL/WASF1/MAGI2/ACAP2/HSPA5/CDC5L/CORO1A	12
BP	GO:0002902	regulation of B cell apoptotic process	6/2486	18/18670	0.02471	0.1297	0.1016	BCL10/BTK/MIR17HG/IRS2/IL2/LYN	6
BP	GO:0007221	positive regulation of transcription of Notch receptor target	6/2486	18/18670	0.02471	0.1297	0.1016	EP300/HEYL/PBX1/CREBBP/NOTCH1/NOTCH3	6
BP	GO:0034199	activation of protein kinase A activity	6/2486	18/18670	0.02471	0.1297	0.1016	ADCY3/PRKAR2A/ADCY7/ADCY4/ADCY6/PRKAR2B	6
BP	GO:0043011	myeloid dendritic cell differentiation	6/2486	18/18670	0.02471	0.1297	0.1016	TGFB1/BATF2/IRF4/TRAF6/BATF/BATF3	6
BP	GO:0043555	regulation of translation in response to stress	6/2486	18/18670	0.02471	0.1297	0.1016	RBM4/PPP1R15A/PPP1R15B/EIF2AK4/EIF2S1/SESN2	6
BP	GO:0150078	positive regulation of neuroinflammatory response	6/2486	18/18670	0.02471	0.1297	0.1016	MMP8/TNF/NUPR1/IL1B/IL33/TREM2	6
BP	GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	6/2486	18/18670	0.02471	0.1297	0.1016	TNRC6B/ZFP36/POLR2G/BTG2/CNOT7/CNOT1	6
BP	GO:2000479	regulation of cAMP-dependent protein kinase activity	6/2486	18/18670	0.02471	0.1297	0.1016	PRKAR2A/SIRT1/SESN2/PKIB/MST1/PRKAR2B	6
BP	GO:0045428	regulation of nitric oxide biosynthetic process	15/2486	66/18670	0.0248	0.1301	0.1019	CLU/HBB/DDAH1/MMP8/TNF/HSP90AA1/ZC3H12A/ASS1/KLF4/CD34/ACP5/IL1B/HSP90AB1/CAV1/MTOR	15
BP	GO:0000082	G1/S transition of mitotic cell cycle	49/2486	279/18670	0.02504	0.1309	0.1026	MUC1/IQGAP3/CRADD/ACVR1/PRIM2/CNOT8/CNOT4/POLE3/INHBA/EP300/RPS27L/TAF10/MTBP/KANK2/CCND1/CTDSPL/CDKN2C/MIR21/POLE/MDM4/MAX/EGFR/PML/PLCB1/CDK2AP2/CDC45/DBF4/KCNA5/PLK3/KLF4/BTG2/CRLF3/KHDRBS1/CDKN2B/SKP2/GPNMB/MIR214/FAM107A/CNOT7/TRIAP1/TNKS1BP1/E2F8/PSME1/CDKN3/HYAL1/KIF14/CNOT1/CUL1/MCM5	49
BP	GO:0030513	positive regulation of BMP signaling pathway	9/2486	33/18670	0.02506	0.1309	0.1026	PELO/HES1/TWSG1/SULF1/NOTCH1/ZNF423/FKBP8/MSX1/CDH5	9
BP	GO:0032691	negative regulation of interleukin-1 beta production	9/2486	33/18670	0.02506	0.1309	0.1026	TNFAIP3/GHRL/CX3CL1/ZC3H12A/PML/IGF1/ACP5/TREM2/NLRP7	9
BP	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	9/2486	33/18670	0.02506	0.1309	0.1026	TNFAIP3/APC/CDKN1C/IPO7/CDKN2C/NR2F2/PLK1/CDKN2B/IPO5	9
BP	GO:0048536	spleen development	9/2486	33/18670	0.02506	0.1309	0.1026	EPB42/POLB/FADD/PPP2R3C/NFKB2/PBX1/JARID2/CDKN2B/RC3H1	9
BP	GO:0051090	regulation of DNA-binding transcription factor activity	72/2486	432/18670	0.02512	0.1309	0.1026	CLU/SRI/ANXA3/TNFAIP3/KEAP1/PPARG/EP300/HEYL/NFKB2/NFKBIA/MAPK11/PRKCB/EIF2AK4/TNF/TWIST1/SMAD7/JUN/BCL10/LTF/DHX9/NFKBIE/TGFB1/PINK1/PHB2/PRDX2/BHLHE40/TRIM21/UBA52/GAS6/ITCH/CX3CL1/PPRC1/ZC3H12A/MED13/ZBTB7A/FOS/G3BP2/BTK/USP7/SIRT1/DDIT3/TRAF6/JUP/CYLD/RELA/TNFRSF11A/TAF3/FOXS1/SFRP4/SMO/GLIS2/POU4F1/KLF4/RAB7B/RLIM/NUPR1/NDP/IL1B/UBC/WNT5A/FLNA/TLR9/ROR1/DDR2/CAV1/HCLS1/TAF1/FZD4/WFS1/RPS6KA5/NR1H4/ADORA3	72
BP	GO:0001894	tissue homeostasis	41/2486	227/18670	0.02512	0.1309	0.1026	ITGB3/INPP5D/TNFAIP3/GATA1/CSF1/LIPA/TUB/TMEM119/LTF/LDB1/ABCA4/FOXC1/CLN8/SPP1/TRAF6/WWTR1/MDM1/EGFR/NOS3/HSPB1/P2RX7/PIGR/PTH1R/BBS1/TNFRSF11A/SMO/SOX9/CD34/NOTCH1/ACP5/SERPINA3/YAP1/CIB2/MUC2/NOX4/TLR9/PDK4/BARD1/CORO1A/LPCAT1/ZNF830	41
BP	GO:0072175	epithelial tube formation	26/2486	132/18670	0.02514	0.1309	0.1026	ARID1A/IRX2/TWIST1/BCL10/TGFB2/TGFB1/PHACTR4/LUZP1/IRX3/TRAF6/SFRP2/LIAS/SIX1/STK4/SEC24B/SOX9/CTHRC1/SFRP1/WNT5A/PODXL/RPS7/DLC1/PFN1/SPINT2/SETD2/MTHFR	26
BP	GO:0046883	regulation of hormone secretion	47/2486	266/18670	0.02516	0.131	0.1026	SRI/LRP5L/SYTL4/ITPR1/CDK16/INHBA/SLC25A5/CACNA2D2/TNF/GHRL/SCT/SERP1/TRH/RAB11FIP1/PFKFB2/RAB11FIP5/CREB1/C2CD2L/ICA1/ADRA2A/RAPGEF3/EDN3/SPP1/JAGN1/TM7SF3/EGFR/SLC25A6/IRS2/KCNA5/AGTR1/C1QTNF1/BMP8A/IL1B/STX4/FKBP1B/SFRP1/PPP3CB/PSMD9/REST/CAPN10/ADCYAP1/KCNS3/MIDN/NR1H4/LRP5/RAPGEF4/ABAT	47
BP	GO:0001764	neuron migration	30/2486	157/18670	0.02532	0.1317	0.1032	NRCAM/FGF13/ZNF609/LHX6/NIPBL/TWIST1/CRKL/NRP1/GAS6/CX3CL1/NTRK2/CXCL12/ITGA3/SATB2/FLRT2/LRP12/NR2F2/LRIG2/DCLK1/IGSF10/MATN2/CDK5R1/FLNA/NDN/NDE1/NR4A2/GPR173/MYH10/MARK1/AXL	30
BP	GO:0070646	protein modification by small protein removal	52/2486	299/18670	0.02547	0.1322	0.1037	PSMD14/PSMD12/POLB/TNFAIP3/OTUD4/KEAP1/TOMM20/YY1/EP300/SPATA2/NFKBIA/APC/USP9Y/TAF10/SMAD7/USP10/PSMD7/PSMB5/TRIM21/USPL1/UBA52/ITCH/TNIP1/SMAD1/UBXN1/ZC3H12A/TRRAP/USP28/USP7/MDM4/TRAF6/IFIH1/CYLD/SENP6/UCHL1/EIF3F/USP42/VCP/PSMB7/FOXK2/HCFC1/OTUD7B/PSMD1/IL33/PSMD9/SKP2/UBC/SUDS3/USP33/SENP7/PSME1/BARD1	52
BP	GO:0038034	signal transduction in absence of ligand	16/2486	72/18670	0.02552	0.1322	0.1037	MKNK2/FADD/INHBA/GATA1/TNF/STRADB/LCN2/PRDX2/MOAP1/CX3CL1/BCL2L1/IL2/MCL1/IFI6/IL1B/BAK1	16
BP	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand	16/2486	72/18670	0.02552	0.1322	0.1037	MKNK2/FADD/INHBA/GATA1/TNF/STRADB/LCN2/PRDX2/MOAP1/CX3CL1/BCL2L1/IL2/MCL1/IFI6/IL1B/BAK1	16
BP	GO:1902036	regulation of hematopoietic stem cell differentiation	16/2486	72/18670	0.02552	0.1322	0.1037	PSMD14/PSMD12/GATA1/YTHDF2/PSMD7/TAL1/PSMB5/LDB1/ITCH/FOXC1/PSMB7/YAP1/PSMD1/PSMD9/PSME1/HSPA9	16
BP	GO:0051403	stress-activated MAPK cascade	50/2486	286/18670	0.02569	0.133	0.1043	MMP8/MAPK11/TNF/DLG1/DUSP10/DNAJA1/TGFB2/CRKL/PINK1/ZFP36/TRAF4/UBA52/ITCH/PPEF2/FCGR2B/ERN1/ZC3H12A/IGF1R/BMP2/PTGER4/TRAF6/MAP3K2/EGFR/CYLD/SFRP2/SAMD5/MAP3K5/TPD52L1/PLCB1/TNFRSF11A/FZD10/MID1/IL1B/CCL21/SFRP1/FZD5/UBC/PDCD10/WNT5A/TLR9/IL26/DUSP1/MAP3K3/SH2D3C/FZD4/CDC42EP5/CRYAB/PER1/CUL1/RASSF2	50
BP	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	24/2486	120/18670	0.02584	0.133	0.1043	RPS27/RPS28/PNRC2/PPP2CA/RPS15/UBA52/RPS26/RPLP1/RPL28/RPS3A/DCP2/RPL10/RPL29/RPS8/RPS4Y1/RPS2/RPL39/RPS10/RPL6/SMG6/RPL14/RPS7/RPL9/RPL15	24
BP	GO:0003180	aortic valve morphogenesis	8/2486	28/18670	0.02586	0.133	0.1043	HEYL/TWIST1/TGFB1/ELN/NOS3/SOX9/NOTCH1/SLIT2	8
BP	GO:0033137	negative regulation of peptidyl-serine phosphorylation	8/2486	28/18670	0.02586	0.133	0.1043	SMAD7/BDKRB2/PPM1F/CAV1/INPP5F/BAK1/DMD/RASSF2	8
BP	GO:0036296	response to increased oxygen levels	8/2486	28/18670	0.02586	0.133	0.1043	POLB/PPARG/ATP6V0A2/KCNA5/PDGFRB/TMEM199/POLG/CAV1	8
BP	GO:0045577	regulation of B cell differentiation	8/2486	28/18670	0.02586	0.133	0.1043	INPP5D/INHBA/PPP2R3C/BTK/CYLD/MIR17HG/SFRP1/TLR9	8
BP	GO:1902745	positive regulation of lamellipodium organization	8/2486	28/18670	0.02586	0.133	0.1043	WASF2/AKIRIN1/ARHGEF7/ENPP2/NCKAP1/RREB1/ARPC2/MTOR	8
BP	GO:0035561	regulation of chromatin binding	7/2486	23/18670	0.02593	0.133	0.1043	TDG/PARP9/NFATC4/DDX11/DTX3L/EBF2/BTAF1	7
BP	GO:0051043	regulation of membrane protein ectodomain proteolysis	7/2486	23/18670	0.02593	0.133	0.1043	TNF/ADRA2A/TIMP3/LRIG2/IL1B/TIMP4/SH3D19	7
BP	GO:1901889	negative regulation of cell junction assembly	7/2486	23/18670	0.02593	0.133	0.1043	ARHGAP6/TNF/ACE/CLASP2/PHLDB2/FAM107A/DLC1	7
BP	GO:1903429	regulation of cell maturation	7/2486	23/18670	0.02593	0.133	0.1043	SIRT2/EDNRB/BCL11A/YTHDF2/TRIM58/MTOR/KIF14	7
BP	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	64/2486	379/18670	0.02594	0.133	0.1043	TRA2B/RBM4/CPSF7/SRRM1/PHF5A/SF3B2/SF3B5/LSM4/MBNL1/RBM22/PPIL1/WTAP/SYF2/SRRM2/YTHDC1/CLNS1A/PAPOLA/DDX42/NOL3/SFPQ/DHX9/HNRNPM/LSM7/FUS/WBP11/RBM7/RSRC1/SRPK2/SF3B4/U2AF1L4/RBM3/RBMX2/CWC25/ZBTB7A/PQBP1/RBMXL1/POLR2G/U2AF1/GEMIN6/PABPN1/JMJD6/TRA2A/ZCCHC8/HNRNPK/SNRPB/CELF1/ZC3H10/YBX1/PCF11/HNRNPUL1/KHDRBS1/MFAP1/KHDRBS3/REST/SF3B1/RBMX/HNRNPH2/SMNDC1/MBNL2/PCBP2/CDC5L/POLR2D/CDK13/DDX46	64
BP	GO:0000398	mRNA splicing, via spliceosome	64/2486	379/18670	0.02594	0.133	0.1043	TRA2B/RBM4/CPSF7/SRRM1/PHF5A/SF3B2/SF3B5/LSM4/MBNL1/RBM22/PPIL1/WTAP/SYF2/SRRM2/YTHDC1/CLNS1A/PAPOLA/DDX42/NOL3/SFPQ/DHX9/HNRNPM/LSM7/FUS/WBP11/RBM7/RSRC1/SRPK2/SF3B4/U2AF1L4/RBM3/RBMX2/CWC25/ZBTB7A/PQBP1/RBMXL1/POLR2G/U2AF1/GEMIN6/PABPN1/JMJD6/TRA2A/ZCCHC8/HNRNPK/SNRPB/CELF1/ZC3H10/YBX1/PCF11/HNRNPUL1/KHDRBS1/MFAP1/KHDRBS3/REST/SF3B1/RBMX/HNRNPH2/SMNDC1/MBNL2/PCBP2/CDC5L/POLR2D/CDK13/DDX46	64
BP	GO:0001910	regulation of leukocyte mediated cytotoxicity	17/2486	78/18670	0.02602	0.1332	0.1044	FAM49B/CD1C/FADD/ARG1/FCGR2B/CD1B/IL23R/VAV1/P2RX7/CXCL6/HLA-B/CEACAM1/IL12A/SERPINB9/PPP3CB/PTPRC/HLA-A	17
BP	GO:0002886	regulation of myeloid leukocyte mediated immunity	13/2486	55/18670	0.02606	0.1332	0.1044	PDPK1/CD177/ARG1/STXBP1/FCGR2B/DDX21/BTK/C12orf4/CXCL6/IL13RA2/STX4/CD300A/LYN	13
BP	GO:0048016	inositol phosphate-mediated signaling	13/2486	55/18670	0.02606	0.1332	0.1044	ITPR1/FHL2/TNF/SPPL3/LMCD1/RCAN2/NFATC4/EDN3/IGF1/HRH1/PPP3CB/MTOR/NFATC3	13
BP	GO:0061098	positive regulation of protein tyrosine kinase activity	13/2486	55/18670	0.02606	0.1332	0.1044	BDNF/GHRL/UNC119/TAL1/GAS6/ACE/FBXW7/ADRA2A/NTRK2/EGF/AFAP1L2/NEDD9/NOX4	13
BP	GO:0014910	regulation of smooth muscle cell migration	18/2486	84/18670	0.02634	0.1344	0.1053	SSH1/TPM1/SORL1/NRP1/ACE/MIR21/IGF1/SEMA6D/IGFBP5/PDGFRB/HAS2/PLXNA1/NOX4/MIR214/SLIT2/POSTN/ITGA2/IGFBP3	18
BP	GO:0050886	endocrine process	18/2486	84/18670	0.02634	0.1344	0.1053	SUCNR1/MME/CTSG/INHBA/GHRL/RAB11FIP1/RAB11FIP5/ACE/GJA5/EDN3/HSD11B2/NOS3/AGTR1/C1QTNF1/IL1B/OXTR/FZD4/ENPEP	18
BP	GO:1902806	regulation of cell cycle G1/S phase transition	37/2486	202/18670	0.02641	0.1345	0.1054	MUC1/CRADD/CNOT8/CNOT4/EP300/RPS27L/MTBP/PHB2/KANK2/FBXW7/CCND1/CTDSPL/CDKN2C/MIR21/MDM4/EGFR/PML/PLCB1/CDK2AP2/CDC45/KCNA5/PLK3/KLF4/BTG2/CDKN2B/GPNMB/MIR214/FAM107A/CNOT7/TRIAP1/TNKS1BP1/TAF1/E2F8/PSME1/HYAL1/KIF14/CNOT1	37
BP	GO:0061756	leukocyte adhesion to vascular endothelial cell	11/2486	44/18670	0.02644	0.1345	0.1054	ITGA4/TNF/ELANE/SELP/MIR21/TRAF6/RELA/CXCL12/KLF4/CCL21/SPN	11
BP	GO:1903573	negative regulation of response to endoplasmic reticulum stress	11/2486	44/18670	0.02644	0.1345	0.1054	CLU/PPP1R15A/PPP1R15B/HYOU1/HERPUD1/UBXN1/BCL2L1/CREB3L1/UBE2G2/WFS1/HSPA5	11
BP	GO:1904407	positive regulation of nitric oxide metabolic process	11/2486	44/18670	0.02644	0.1345	0.1054	CLU/HBB/DDAH1/MMP8/TNF/HSP90AA1/ASS1/KLF4/IL1B/HSP90AB1/MTOR	11
BP	GO:0002367	cytokine production involved in immune response	21/2486	102/18670	0.02649	0.1345	0.1054	ARG1/TRIM6/TNF/SMAD7/DLG1/BCL10/TGFB2/IL1R1/TGFB1/GAS6/DDX21/BTK/SIRT1/TRAF6/IL12A/TNFRSF14/IL1B/FZD5/WNT5A/TRIL/RSAD2	21
BP	GO:0001843	neural tube closure	19/2486	90/18670	0.02651	0.1345	0.1054	ARID1A/TWIST1/BCL10/TGFB2/TGFB1/PHACTR4/TRAF6/SFRP2/LIAS/SEC24B/CTHRC1/SFRP1/WNT5A/RPS7/DLC1/PFN1/SPINT2/SETD2/MTHFR	19
BP	GO:0042475	odontogenesis of dentin-containing tooth	19/2486	90/18670	0.02651	0.1345	0.1054	FAM20A/CNNM4/HTRA1/CSF1/SMPD3/JAG2/FOXC1/BMP2/TRAF6/DMRT3/PDGFRA/SMO/DLX3/GLI3/MSX1/TBX1/TNC/ROGDI/LHX8	19
BP	GO:0002700	regulation of production of molecular mediator of immune response	27/2486	139/18670	0.02692	0.1365	0.107	PARP3/ARG1/TRIM6/TNF/SMAD7/BCL10/TGFB2/IL1R1/CD244/TGFB1/FCGR2B/DDX21/BTK/EXOSC3/TRAF6/IL13RA2/IL2/TNFRSF14/IL1B/STX4/IL33/FZD5/WNT5A/TLR9/TRIL/PTPRC/RSAD2	27
BP	GO:0071897	DNA biosynthetic process	36/2486	196/18670	0.02717	0.1376	0.1079	POLB/CHRAC1/PPARG/PARP3/RFC1/POLE3/USP10/LIN9/UBA52/HSP90AA1/SMPD3/DCP2/TELO2/FBXO4/POLE/SIRT1/LOX/SMOC2/PKIB/VCP/RCHY1/CCT8/KLF4/PDGFRB/TK1/POLG/UBC/NOX4/SMG6/PAK3/DUSP1/HSP90AB1/MAPKAPK5/TNKS1BP1/NHP2/NEK2	36
BP	GO:0002287	alpha-beta T cell activation involved in immune response	14/2486	61/18670	0.02726	0.1376	0.1079	SMAD7/MIR21/ZC3H12A/IRF4/NFKBIZ/HLX/PTGER4/IL23R/BATF/TMEM98/IL2/MTOR/SPN/RC3H1	14
BP	GO:0002293	alpha-beta T cell differentiation involved in immune response	14/2486	61/18670	0.02726	0.1376	0.1079	SMAD7/MIR21/ZC3H12A/IRF4/NFKBIZ/HLX/PTGER4/IL23R/BATF/TMEM98/IL2/MTOR/SPN/RC3H1	14
BP	GO:0006879	cellular iron ion homeostasis	14/2486	61/18670	0.02726	0.1376	0.1079	ALAS2/SRI/LTF/FXN/IREB2/LCN2/ABCB6/ABCG2/ATP6V0A2/ABCB7/TMEM199/CP/HEPH/CUL1	14
BP	GO:1903902	positive regulation of viral life cycle	14/2486	61/18670	0.02726	0.1376	0.1079	STOM/CAV2/TRIM21/ADARB1/SRPK2/PPID/LARP1/VPS37B/IFIT1/NOTCH1/PKN2/CNOT7/STAU1/NR5A2	14
BP	GO:0043467	regulation of generation of precursor metabolites and energy	30/2486	158/18670	0.0274	0.1381	0.1082	SLC25A33/SNCA/NUP93/PINK1/PHB2/PFKFB2/FLCN/ZBTB7A/NUP50/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/VCP/RAE1/NUP188/COX7A1/NUP160/IRS2/NUP54/NUP214/IDE/NUP155/KHK/NUPR1/SLC2A6/PRKAG2/SORBS1/MTOR	30
BP	GO:0060402	calcium ion transport into cytosol	30/2486	158/18670	0.0274	0.1381	0.1082	SRI/PDPK1/ITPR1/SNCA/MCOLN3/NOL3/TGFB1/CACNB3/DIAPH1/FAM155A/CX3CL1/DDIT3/P2RX7/PML/PLCB2/PLCB1/RAMP3/APLNR/IBTK/FKBP1B/CCL21/THY1/ANK2/RYR2/CAV1/LYN/BAK1/DMD/PTPRC/CORO1A	30
BP	GO:0042770	signal transduction in response to DNA damage	26/2486	133/18670	0.02741	0.1381	0.1082	MUC1/PMAIP1/CRADD/CNOT8/CNOT4/EP300/RPS27L/TWIST1/USP10/PPM1D/MIR21/SIRT1/MDM4/SESN2/BATF/PML/PLK3/PLK1/BTG2/MSX1/CNOT7/TRIAP1/TNKS1BP1/E2F8/CDC5L/CNOT1	26
BP	GO:0051701	interaction with host	38/2486	209/18670	0.02747	0.1382	0.1083	ITGB3/RRAGA/ITGB5/EIF2AK4/CAV2/TGFB1/IFITM3/THOC2/TRIM21/GAS6/ITCH/TNIP1/PPID/ZC3H12A/KPNA1/EGFR/BCL2L1/PML/NUP153/PABPN1/KPNA3/VPS37B/CBL/IFIT1/EFNB2/IDE/SERPINB9/TNFRSF14/IFITM2/UVRAG/CCL8/CAV1/GYPA/ITGA2/GPR15/KPNA4/HYAL1/AXL	38
BP	GO:0048638	regulation of developmental growth	59/2486	347/18670	0.0278	0.1398	0.1096	NRCAM/CTTN/FGF13/YY1/SEMA3B/BDNF/RNF6/MAPK11/PLXNA3/CSF1/NIPBL/BCL11A/TBX5/CACNA2D2/DUSP10/FXN/GHRL/AGRN/RND2/SERP1/CREB1/SEMA3G/NRP1/L1CAM/FN1/FOXC1/HLX/SPP1/SFRP2/SEMA4D/ULK2/IGF1/CXCL12/SEMA6D/SEMA5B/ITSN2/SIX1/PLCB1/MIR17HG/MAP2/STK4/FOXS1/SMO/MTM1/TBX2/NOTCH1/YAP1/JARID2/SFRP1/ZFPM2/CDK5R1/WNT5A/STC2/MTOR/GHR/SEMA3E/SIN3A/PIN1/GDI1	59
BP	GO:0030968	endoplasmic reticulum unfolded protein response	24/2486	121/18670	0.0283	0.1422	0.1114	PPP1R15A/PPP1R15B/MBTPS1/EDEM1/EP300/HSP90B1/SERP1/HYOU1/HERPUD1/EIF2S1/CCND1/ERN1/SSR1/DDX11/DDIT3/DERL1/TBL2/VCP/CREB3L1/KDELR3/STC2/BAK1/WFS1/HSPA5	24
BP	GO:0019048	modulation by virus of host morphology or physiology	10/2486	39/18670	0.02837	0.1423	0.1116	RRAGA/EIF2AK4/TGFB1/ZC3H12A/KPNA1/BCL2L1/PABPN1/KPNA3/CCL8/KPNA4	10
BP	GO:1904591	positive regulation of protein import	10/2486	39/18670	0.02837	0.1423	0.1116	RBM22/TGFB1/ZC3H12A/JUP/SMO/GLI3/IPO5/FLNA/HCLS1/PDCD5	10
BP	GO:0001961	positive regulation of cytokine-mediated signaling pathway	12/2486	50/18670	0.02843	0.1425	0.1117	FADD/CASP4/CSF1/TRIM6/IL1R1/GAS6/PARP9/CD300LF/TREM2/WNT5A/AXL/TRIM44	12
BP	GO:0000075	cell cycle checkpoint	39/2486	216/18670	0.0285	0.1426	0.1118	MUC1/CRADD/CNOT8/CNOT4/EP300/RPS27L/SYF2/APC/EIF2AK4/DLG1/TGFB1/CCND1/MIR21/FBXO4/USP28/MDM4/BCL2L1/PML/FOXN3/BUB1B/WAC/CDC45/WNT9A/PLK3/PLK1/NSUN2/BTG2/CDKN2B/CHFR/DUSP1/CNOT7/TTK/TRIAP1/TNKS1BP1/E2F8/MUS81/CDC5L/CNOT1/ZNF830	39
BP	GO:0022409	positive regulation of cell-cell adhesion	45/2486	255/18670	0.0285	0.1426	0.1118	FAM49B/PDPK1/HLA-DPB1/FADD/ITGA4/TNF/SMAD7/DUSP10/BCL10/TGFB1/IGFBP2/ELANE/CD276/HES1/CX3CL1/CD83/MIR21/NFKBIZ/HLX/TRAF6/IL23R/CYLD/VAV1/CEACAM6/IGF1/RELA/PDPN/PDCD1LG2/IL12A/EFNB2/IL2/HAS2/TNFRSF14/GLI3/IL1B/CCL21/THY1/WNT5A/PAK3/PODXL/CAV1/LYN/PTPRC/CORO1A/DOCK8	45
BP	GO:0032612	interleukin-1 production	23/2486	115/18670	0.02868	0.1433	0.1123	SUCNR1/ORM1/TNFAIP3/ARG2/LPL/GHRL/IFI16/GAS6/CX3CL1/ZC3H12A/HSPB1/P2RX7/PML/IGF1/CEACAM1/ACP5/IL1B/TREM2/FZD5/NLRP1/WNT5A/NR1H4/NLRP7	23
BP	GO:0007568	aging	55/2486	321/18670	0.02869	0.1433	0.1123	C1QA/MSH6/MME/INPP5D/POLB/JUND/EDNRB/ARG2/ARG1/NFKB2/SNCA/SMC5/TWIST1/JUN/TGFB1/IGFBP2/SERP1/CREB1/CDKN1C/EIF2S1/CX3CL1/MIR21/CLN8/FBXO4/FOS/RSL1D1/SIRT1/SERPING1/PML/RELA/VASH1/ASS1/PTH1R/COL4A2/GJB6/IGFBP5/IDE/PDGFRB/TBX2/SLC32A1/POLG/CDKN2B/LIMS1/NOX4/DCN/MAP3K3/MAPKAPK5/MTOR/BAK1/KL/PRELP/CRYAB/SIN3A/NQO1/ABAT	55
BP	GO:2000045	regulation of G1/S transition of mitotic cell cycle	34/2486	184/18670	0.02873	0.1434	0.1124	MUC1/CRADD/CNOT8/CNOT4/EP300/RPS27L/MTBP/KANK2/CCND1/CTDSPL/CDKN2C/MIR21/MDM4/EGFR/PML/PLCB1/CDK2AP2/CDC45/KCNA5/PLK3/KLF4/BTG2/CDKN2B/GPNMB/MIR214/FAM107A/CNOT7/TRIAP1/TNKS1BP1/E2F8/PSME1/HYAL1/KIF14/CNOT1	34
BP	GO:0032945	negative regulation of mononuclear cell proliferation	16/2486	73/18670	0.02877	0.1434	0.1124	INPP5D/ARG2/ARG1/DLG1/TGFB1/FCGR2B/TWSG1/BTK/PDCD1LG2/IL2/TNFRSF14/GPNMB/CD300A/LYN/SPN/RC3H1	16
BP	GO:0050672	negative regulation of lymphocyte proliferation	16/2486	73/18670	0.02877	0.1434	0.1124	INPP5D/ARG2/ARG1/DLG1/TGFB1/FCGR2B/TWSG1/BTK/PDCD1LG2/IL2/TNFRSF14/GPNMB/CD300A/LYN/SPN/RC3H1	16
BP	GO:0008380	RNA splicing	77/2486	469/18670	0.02906	0.1444	0.1132	TRA2B/RBM4/CPSF7/SRRM1/PHF5A/SF3B2/SF3B5/LSM4/MBNL1/RBM22/PPIL1/WTAP/SYF2/AKAP8L/SRRM2/CLK1/YTHDC1/CLNS1A/PAPOLA/DDX42/NOL3/PPP2CA/SFPQ/DHX9/HNRNPM/THOC2/ZC3H13/LSM7/FUS/WBP11/RBM7/RSRC1/SRPK2/PRPF38B/SF3B4/U2AF1L4/ERN1/RPS26/RBM3/RBMX2/CWC25/ZBTB7A/PQBP1/RBMXL1/POLR2G/U2AF1/GEMIN6/PABPN1/JMJD6/TRA2A/ZCCHC8/HNRNPK/SNRPB/CELF1/AHNAK/CLK3/ZC3H10/YBX1/PCF11/HNRNPUL1/KHDRBS1/MFAP1/KHDRBS3/REST/SF3B1/RBMX/NONO/HNRNPH2/SMNDC1/MBNL2/ZBTB8OS/PCBP2/CDC5L/POLR2D/CDK13/DDX46/ZNF830	77
BP	GO:0043270	positive regulation of ion transport	48/2486	275/18670	0.02907	0.1444	0.1132	SRI/SCN1B/SLC9A3R1/PDPK1/ARF1/SNCA/DLG1/ATP1B2/PINK1/CYP4F2/TRH/FGF14/CACNB3/STXBP1/ADRA2A/CX3CL1/MIR21/P2RY12/EDN3/STAC/STC1/P2RX7/MCHR1/CXCL12/STAC2/TNFRSF11A/RAMP3/FXYD1/APLNR/PDGFRB/KCNA1/IL1B/THY1/TREM2/ANK2/FLNA/RYR2/CAV1/TRIAP1/BAK1/DMD/ARC/WFS1/EPHB2/FABP3/SLC6A1/SHANK3/ABAT	48
BP	GO:0071260	cellular response to mechanical stimulus	17/2486	79/18670	0.02917	0.1444	0.1132	CRADD/FADD/IRF1/BCL10/TGFB1/PDE2A/MAP3K14/PTGER4/MAP3K2/EGFR/MAP3K1/TMEM150C/AQP1/SOX9/IL1B/BAK1/ITGA2	17
BP	GO:0032091	negative regulation of protein binding	21/2486	103/18670	0.02924	0.1444	0.1132	SLPI/ITGA4/TDG/SORL1/ACE/EIF2S1/CRMP1/NFATC4/DAB2/DDX11/CFHR2/PTPRF/MAP2/TTBK2/IFIT1/NES/USP33/CAV1/GPSM1/HSPA5/PIN1	21
BP	GO:0032652	regulation of interleukin-1 production	21/2486	103/18670	0.02924	0.1444	0.1132	ORM1/TNFAIP3/ARG2/LPL/GHRL/IFI16/GAS6/CX3CL1/ZC3H12A/HSPB1/P2RX7/PML/IGF1/CEACAM1/ACP5/TREM2/FZD5/NLRP1/WNT5A/NR1H4/NLRP7	21
BP	GO:1902106	negative regulation of leukocyte differentiation	21/2486	103/18670	0.02924	0.1444	0.1132	C1QC/INPP5D/INHBA/PGLYRP1/IRF1/SMAD7/HOXA7/LTF/PRDX2/FBXW7/FCGR2B/MIR21/ZC3H12A/HLX/CEACAM1/IL2/GLI3/SFRP1/LYN/FBN1/RC3H1	21
BP	GO:0034620	cellular response to unfolded protein	27/2486	140/18670	0.02926	0.1444	0.1132	PPP1R15A/PPP1R15B/MBTPS1/EDEM1/EP300/HSP90B1/SERP1/HYOU1/HERPUD1/EIF2S1/CCND1/ERN1/SSR1/DDX11/DDIT3/TM7SF3/DERL1/TBL2/VCP/CREB3L1/KDELR3/STC2/BAK1/WFS1/HSPA5/HSPB8/HSPA9	27
BP	GO:0050707	regulation of cytokine secretion	38/2486	210/18670	0.02937	0.1444	0.1132	ORM1/MMP8/TNFAIP3/ARG2/MBP/MAPK11/TRIM6/TNF/TWIST1/LPL/GHRL/DHX9/CD244/GAS6/FCGR2B/CX3CL1/ZC3H12A/FN1/PTGER4/IFIH1/P2RX7/PML/TNFRSF14/CD34/IL1B/IL33/FZD5/SSC5D/NLRP1/WNT5A/TLR9/IL26/LYN/POSTN/FRMD8/NR1H4/SYT11/NLRP7	38
BP	GO:1903901	negative regulation of viral life cycle	18/2486	85/18670	0.02939	0.1444	0.1132	SLPI/TRIM6/EIF2AK4/TNF/LTF/IFITM3/TRIM21/IFI16/TNIP1/SRPK2/ZC3H12A/ILF3/PML/IFIT1/IFIT5/IFITM2/CCL8/RSAD2	18
BP	GO:0014020	primary neural tube formation	20/2486	97/18670	0.0294	0.1444	0.1132	ARID1A/TWIST1/BCL10/TGFB2/TGFB1/PHACTR4/LUZP1/TRAF6/SFRP2/LIAS/SEC24B/CTHRC1/SFRP1/WNT5A/RPS7/DLC1/PFN1/SPINT2/SETD2/MTHFR	20
BP	GO:0048709	oligodendrocyte differentiation	20/2486	97/18670	0.0294	0.1444	0.1132	CLU/PPARG/WASF3/CD9/DUSP10/TGFB1/DAAM2/HES1/CDKN2C/NTRK2/PTN/TMEM98/SOX9/NOTCH1/GLI3/MTOR/LYN/OLIG1/SOX6/EIF2B2	20
BP	GO:0060606	tube closure	19/2486	91/18670	0.02946	0.1444	0.1132	ARID1A/TWIST1/BCL10/TGFB2/TGFB1/PHACTR4/TRAF6/SFRP2/LIAS/SEC24B/CTHRC1/SFRP1/WNT5A/RPS7/DLC1/PFN1/SPINT2/SETD2/MTHFR	19
BP	GO:0003214	cardiac left ventricle morphogenesis	5/2486	14/18670	0.02952	0.1444	0.1132	TBX5/SFRP2/CPE/NOTCH1/RYR2	5
BP	GO:0021692	cerebellar Purkinje cell layer morphogenesis	5/2486	14/18670	0.02952	0.1444	0.1132	FAIM2/HERC1/LDB1/AGTPBP1/KIF14	5
BP	GO:0030207	chondroitin sulfate catabolic process	5/2486	14/18670	0.02952	0.1444	0.1132	IDS/BGN/DCN/CSPG4/HYAL1	5
BP	GO:0043455	regulation of secondary metabolic process	5/2486	14/18670	0.02952	0.1444	0.1132	ASIP/MIR21/SLC24A5/WNT5A/GIPC1	5
BP	GO:0051852	disruption by host of symbiont cells	5/2486	14/18670	0.02952	0.1444	0.1132	CTSG/ARG1/ELANE/CAMP/CXCL6	5
BP	GO:0060009	Sertoli cell development	5/2486	14/18670	0.02952	0.1444	0.1132	RAB13/ARID4A/SOX9/NUP210L/FLNA	5
BP	GO:0071941	nitrogen cycle metabolic process	5/2486	14/18670	0.02952	0.1444	0.1132	ARG2/ARG1/ASS1/CPS1/NR1H4	5
BP	GO:0072567	chemokine (C-X-C motif) ligand 2 production	5/2486	14/18670	0.02952	0.1444	0.1132	MBP/TNF/LPL/KLF4/POSTN	5
BP	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	5/2486	14/18670	0.02952	0.1444	0.1132	PMAIP1/SKIL/STK4/TIMP3/SFRP1	5
BP	GO:2000345	regulation of hepatocyte proliferation	5/2486	14/18670	0.02952	0.1444	0.1132	TNFAIP3/LIMS2/FBXW7/PTN/CEACAM1	5
BP	GO:2001212	regulation of vasculogenesis	5/2486	14/18670	0.02952	0.1444	0.1132	RAMP2/CEACAM1/EMP2/CD34/KDR	5
BP	GO:0090090	negative regulation of canonical Wnt signaling pathway	33/2486	178/18670	0.02952	0.1444	0.1132	PSMD14/PSMD12/SLC9A3R1/PTPRO/APC/WNT5B/PSMD7/PSMB5/IGFBP2/BMP2/DAB2/DDIT3/WWTR1/CYLD/SFRP2/CSNK1A1/IGFBP4/STK4/SFRP4/PSMB7/SOX9/NOTCH1/GLI3/CTHRC1/PSMD1/SFRP1/PSMD9/WNT5A/CAV1/RBMS3/PSME1/DKK3/LZTS2	33
BP	GO:0010332	response to gamma radiation	13/2486	56/18670	0.02994	0.1462	0.1146	POLB/XRCC6/POLE3/BCL2L1/PML/CBL/YAP1/POLG/NOX4/BAK1/HSPA5/CRYAB/PTPRC	13
BP	GO:0098586	cellular response to virus	13/2486	56/18670	0.02994	0.1462	0.1146	ARF1/MAPK11/TRIM6/VWCE/GPATCH3/ZC3H12A/BCL2L1/IFIH1/TSPAN6/IL12A/IFI6/RNF125/ZCCHC3	13
BP	GO:0000375	RNA splicing, via transesterification reactions	64/2486	382/18670	0.03006	0.1466	0.1149	TRA2B/RBM4/CPSF7/SRRM1/PHF5A/SF3B2/SF3B5/LSM4/MBNL1/RBM22/PPIL1/WTAP/SYF2/SRRM2/YTHDC1/CLNS1A/PAPOLA/DDX42/NOL3/SFPQ/DHX9/HNRNPM/LSM7/FUS/WBP11/RBM7/RSRC1/SRPK2/SF3B4/U2AF1L4/RBM3/RBMX2/CWC25/ZBTB7A/PQBP1/RBMXL1/POLR2G/U2AF1/GEMIN6/PABPN1/JMJD6/TRA2A/ZCCHC8/HNRNPK/SNRPB/CELF1/ZC3H10/YBX1/PCF11/HNRNPUL1/KHDRBS1/MFAP1/KHDRBS3/REST/SF3B1/RBMX/HNRNPH2/SMNDC1/MBNL2/PCBP2/CDC5L/POLR2D/CDK13/DDX46	64
BP	GO:0032892	positive regulation of organic acid transport	9/2486	34/18670	0.03018	0.1468	0.115	CYP4F2/TRH/STXBP1/P2RX7/TNFRSF11A/IL1B/FABP3/SLC6A1/ABAT	9
BP	GO:0043276	anoikis	9/2486	34/18670	0.03018	0.1468	0.115	NTRK2/CEACAM6/DAPK2/BMF/MCL1/NOTCH1/CAV1/MTOR/PDK4	9
BP	GO:0045920	negative regulation of exocytosis	9/2486	34/18670	0.03018	0.1468	0.115	SNCA/FCGR2B/ADRA2A/CEACAM1/IL13RA2/NOTCH1/REST/CD300A/STXBP6	9
BP	GO:1904030	negative regulation of cyclin-dependent protein kinase activity	9/2486	34/18670	0.03018	0.1468	0.115	TNFAIP3/APC/CDKN1C/IPO7/CDKN2C/NR2F2/PLK1/CDKN2B/IPO5	9
BP	GO:0001974	blood vessel remodeling	11/2486	45/18670	0.03091	0.1498	0.1174	NOL3/TGFB1/ACE/FOXC1/NOS3/CEACAM1/BGN/RSPO3/BAK1/HOXA3/AXL	11
BP	GO:0048701	embryonic cranial skeleton morphogenesis	11/2486	45/18670	0.03091	0.1498	0.1174	NIPBL/TWIST1/WDR19/SIX1/PDGFRA/PRRX1/IFT140/TBX15/TBX1/SIX2/SETD2	11
BP	GO:1900271	regulation of long-term synaptic potentiation	11/2486	45/18670	0.03091	0.1498	0.1174	MME/EIF2AK4/SQSTM1/CREB1/YTHDF1/PTN/FAM107A/ARC/STAU1/EPHB2/SHANK3	11
BP	GO:1902743	regulation of lamellipodium organization	11/2486	45/18670	0.03091	0.1498	0.1174	WASF2/AKIRIN1/ARHGEF7/PDPN/ENPP2/NCKAP1/RREB1/MIR214/ARPC2/SLIT2/MTOR	11
BP	GO:0002753	cytoplasmic pattern recognition receptor signaling pathway	14/2486	62/18670	0.03104	0.1498	0.1174	TNFAIP3/NFKBIA/UBA52/ITCH/GPATCH3/TRAF6/IFIH1/CYLD/RELA/TSPAN6/UBC/RNF125/ALPK1/ZCCHC3	14
BP	GO:0060393	regulation of pathway-restricted SMAD protein phosphorylation	14/2486	62/18670	0.03104	0.1498	0.1174	ACVR1/INHBA/SMAD7/TGFB2/TGFB1/TWSG1/BMP2/DAB2/ACVR2A/INHBE/BMP8A/RBPMS/TTK/PIN1	14
BP	GO:1901862	negative regulation of muscle tissue development	14/2486	62/18670	0.03104	0.1498	0.1174	SIRT2/YY1/MAPK11/TBX5/TWIST1/AKIRIN1/TGFB1/FLCN/BMP2/MIR17HG/IGFBP5/FRS2/JARID2/SOX6	14
BP	GO:0043524	negative regulation of neuron apoptotic process	28/2486	147/18670	0.03105	0.1498	0.1174	NTF3/PDPK1/FAIM2/BDNF/SNCA/JUN/PINK1/HYOU1/NRP1/CRLF1/STXBP1/CX3CL1/NFATC4/BCL2L1/NTRK2/SIX1/POU4F1/BTG2/NES/NONO/NR4A2/HSP90AB1/SET/WFS1/CORO1A/AXL/KIF14/PIN1	28
BP	GO:0061351	neural precursor cell proliferation	28/2486	147/18670	0.03105	0.1498	0.1174	SIRT2/FGF13/DAGLB/LIMS2/VEGFC/TGFB1/CX3CL1/EGF/PTN/NAP1L1/MELK/CDON/SMO/FRS2/NOTCH1/KCNA1/GLI3/BTG2/NES/WNT5A/FLNA/NDE1/EMX2/EML1/LYN/ADCYAP1/SPINT2/KIF14	28
BP	GO:0071236	cellular response to antibiotic	28/2486	147/18670	0.03105	0.1498	0.1174	CLU/ADCY3/MAP1LC3A/TNFAIP3/ARG1/ADCY7/FXN/PINK1/LCN2/KDM6B/LARP1/MIR21/SMPD3/ZC3H12A/PYCR1/DDX11/SIRT1/JAGN1/ADCY6/MAP3K5/RELA/AQP1/KLF4/PDCD10/PCGF2/HSPA5/AXL/NQO1	28
BP	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	42/2486	237/18670	0.03139	0.1511	0.1184	PDPK1/TNFAIP3/ZFAND6/FADD/PRKCB/SQSTM1/TNF/BCL10/LTF/USP10/PINK1/AKAP13/TNIP1/SLC20A1/MAP3K14/CX3CL1/ZC3H12A/TFG/DDX21/REL/SIRT1/TRAF6/ECM1/HSPB1/RELA/PLEKHG5/TSPAN6/PPM1A/IFIT5/OTUD7B/IL1B/CCL21/WNT5A/FLNA/TLR9/ROR1/MAP3K3/SLC44A2/PER1/NR1H4/ALPK1/APOL3	42
BP	GO:0001819	positive regulation of cytokine production	76/2486	464/18670	0.03141	0.1511	0.1184	CLU/FAM49B/ORM1/MMP8/HLA-DPB1/XRCC6/MBP/FADD/IRF8/EP300/NFKB2/MAPK11/TRIM6/ARFGEF2/IRF1/TNF/TWIST1/BCL10/LPL/IL1R1/DHX9/CD244/TGFB1/ELANE/CREB1/CD276/IFI16/GPATCH3/ADRA2A/CX3CL1/CD83/MIR21/CREBBP/IRF4/DDX21/PDE4B/NFATC4/PTGER4/DDIT3/TRAF6/PQBP1/IL23R/IFIH1/HSPB1/P2RX7/RELA/TSPAN6/PLCB1/IL12A/SULF1/IL2/RAB7B/AFAP1L2/TNFRSF14/CD34/IL1B/IL17D/IL33/TREM2/FZD5/NLRP1/RNF125/WNT5A/TLR9/TBC1D23/IL26/POSTN/ADCYAP1/SPN/FRMD8/PTPRC/RSAD2/SETD2/ZCCHC3/CCBE1/NLRP7	76
BP	GO:0002220	innate immune response activating cell surface receptor signaling pathway	23/2486	116/18670	0.03141	0.1511	0.1184	MUC1/PSMD14/PSMD12/CLEC4C/PDPK1/EP300/BCL10/PSMD7/PSMB5/CREBBP/RAF1/TRAF6/RELA/PSMB7/PSMD1/MUC2/PSMD9/PAK3/LYN/MUC3A/PSME1/RPS6KA5/CUL1	23
BP	GO:0034219	carbohydrate transmembrane transport	23/2486	116/18670	0.03141	0.1511	0.1184	GRB10/SLC2A5/CLIP3/RTN2/PRKCB/TNF/FABP5/SESN2/SLC2A8/IGF1/SLC45A1/ADIPOR2/SLC25A27/IRS2/SLC2A6/PRKAG2/IL1B/SORBS1/SLC2A10/SLC2A12/SLC23A1/CAPN10/SLC17A5	23
BP	GO:0016579	protein deubiquitination	49/2486	283/18670	0.0315	0.1511	0.1184	PSMD14/PSMD12/POLB/TNFAIP3/OTUD4/KEAP1/TOMM20/YY1/EP300/SPATA2/NFKBIA/APC/USP9Y/TAF10/SMAD7/USP10/PSMD7/PSMB5/TRIM21/UBA52/ITCH/TNIP1/SMAD1/UBXN1/ZC3H12A/TRRAP/USP28/USP7/MDM4/TRAF6/IFIH1/CYLD/UCHL1/EIF3F/USP42/VCP/PSMB7/FOXK2/HCFC1/OTUD7B/PSMD1/IL33/PSMD9/SKP2/UBC/SUDS3/USP33/PSME1/BARD1	49
BP	GO:0010800	positive regulation of peptidyl-threonine phosphorylation	8/2486	29/18670	0.03167	0.1511	0.1184	CHI3L1/TRIM6/TGFB1/EGF/PLK1/PRKAG2/WNT5A/TNKS1BP1	8
BP	GO:0016577	histone demethylation	8/2486	29/18670	0.03167	0.1511	0.1184	UTY/KDM5D/KDM6B/HSF4/KDM2A/JMJD6/JMJD1C/JARID2	8
BP	GO:0021602	cranial nerve morphogenesis	8/2486	29/18670	0.03167	0.1511	0.1184	PLXNA3/NRP1/ADARB1/SIX1/GLI3/TBX1/EPHB2/HOXA3	8
BP	GO:0030970	retrograde protein transport, ER to cytosol	8/2486	29/18670	0.03167	0.1511	0.1184	SEC61B/EDEM1/HSP90B1/HERPUD1/DERL1/VCP/UBE2G2/AUP1	8
BP	GO:0031365	N-terminal protein amino acid modification	8/2486	29/18670	0.03167	0.1511	0.1184	EP300/NAA16/NAA30/CREBBP/PPM1A/NAA25/METAP1/NAA15	8
BP	GO:0070229	negative regulation of lymphocyte apoptotic process	8/2486	29/18670	0.03167	0.1511	0.1184	ARG2/FADD/BCL10/MIR17HG/IRS2/IL2/TSC22D3/DOCK8	8
BP	GO:0090162	establishment of epithelial cell polarity	8/2486	29/18670	0.03167	0.1511	0.1184	SLC9A3R1/MPP5/PARD3/FRMD4A/HES1/MSN/WNT5A/CLASP1	8
BP	GO:1900181	negative regulation of protein localization to nucleus	8/2486	29/18670	0.03167	0.1511	0.1184	FLCN/FBXO4/TMEM98/DCLK1/OTUD7B/DCLK3/SIN3A/LZTS2	8
BP	GO:1903513	endoplasmic reticulum to cytosol transport	8/2486	29/18670	0.03167	0.1511	0.1184	SEC61B/EDEM1/HSP90B1/HERPUD1/DERL1/VCP/UBE2G2/AUP1	8
BP	GO:2000036	regulation of stem cell population maintenance	8/2486	29/18670	0.03167	0.1511	0.1184	NCOA3/TAL1/ZC3H13/PTN/SMO/YAP1/REST/CNOT1	8
BP	GO:0030111	regulation of Wnt signaling pathway	61/2486	363/18670	0.03175	0.1513	0.1186	GRB10/PSMD14/PSMD12/SLC9A3R1/TNFAIP3/FAM53B/PTPRO/APC/PLEKHA4/PPP2CA/WNT5B/PSMD7/TCF7L1/PSMB5/IGFBP2/DAAM2/NXN/PRDM15/BMP2/NFATC4/DAB2/RNF213/DDIT3/WWTR1/JUP/EGFR/CYLD/SFRP2/ITGA3/EGF/VCP/CSNK1A1/IGFBP4/STK4/ZBED2/CCNY/SULF1/SFRP4/PPM1A/RSPO3/PSMB7/SOX9/NOTCH1/YAP1/TSKU/GLI3/CTHRC1/PSMD1/DACT2/SFRP1/PSMD9/FOXL1/WNT5A/ALPK2/CAV1/RBMS3/PSME1/RNF220/DKK3/LZTS2/PIN1	61
BP	GO:0010812	negative regulation of cell-substrate adhesion	15/2486	68/18670	0.03182	0.1513	0.1186	ARHGAP6/PTPRO/HOXA7/CLASP2/CX3CL1/AP1AR/PHLDB2/NOTCH1/ANGPT2/FBLN1/FAM107A/DLC1/POSTN/FZD4/SEMA3E	15
BP	GO:0035914	skeletal muscle cell differentiation	15/2486	68/18670	0.03182	0.1513	0.1186	MEF2D/HEYL/AKIRIN1/CYP26B1/FOS/SIX1/HLF/NR1D2/CDON/NUPR1/KLF5/NOTCH1/BTG2/GPC1/TBX1	15
BP	GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin	6/2486	19/18670	0.03215	0.1513	0.1186	SUCNR1/MME/CTSG/ACE/GJA5/ENPEP	6
BP	GO:0002710	negative regulation of T cell mediated immunity	6/2486	19/18670	0.03215	0.1513	0.1186	ARG1/SMAD7/FCGR2B/CEACAM1/PPP3CB/PTPRC	6
BP	GO:0007096	regulation of exit from mitosis	6/2486	19/18670	0.03215	0.1513	0.1186	SIRT2/TGFB1/PHB2/ANLN/CDKN1C/UBE2C	6
BP	GO:0007350	blastoderm segmentation	6/2486	19/18670	0.03215	0.1513	0.1186	NRP1/PCSK6/HOXD8/FRS2/FZD5/WNT5A	6
BP	GO:0015669	gas transport	6/2486	19/18670	0.03215	0.1513	0.1186	HBB/HBD/CYGB/HBM/AQP1/HBQ1	6
BP	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway	6/2486	19/18670	0.03215	0.1513	0.1186	ITGB3/GRB10/PRKCB/FLT1/FGF18/IL1B	6
BP	GO:0035493	SNARE complex assembly	6/2486	19/18670	0.03215	0.1513	0.1186	SNCA/STXBP1/STX4/UVRAG/STXBP6/PRRT2	6
BP	GO:0035728	response to hepatocyte growth factor	6/2486	19/18670	0.03215	0.1513	0.1186	SIRT2/CREB1/NRP1/RELA/BCAR1/ADAMTS12	6
BP	GO:0045947	negative regulation of translational initiation	6/2486	19/18670	0.03215	0.1513	0.1186	RBM4/PAIP2B/EIF2AK4/EIF2S1/LARP1/PAIP2	6
BP	GO:0071243	cellular response to arsenic-containing substance	6/2486	19/18670	0.03215	0.1513	0.1186	MKNK2/ZC3H12A/ZFAND2A/VCP/ZFAND1/CPEB2	6
BP	GO:0071435	potassium ion export	6/2486	19/18670	0.03215	0.1513	0.1186	DLG1/MIR21/KCND3/KCNA5/KCNT2/KCNA3	6
BP	GO:0090201	negative regulation of release of cytochrome c from mitochondria	6/2486	19/18670	0.03215	0.1513	0.1186	CLU/FXN/NOL3/BCL2L1/IGF1/TRIAP1	6
BP	GO:0097623	potassium ion export across plasma membrane	6/2486	19/18670	0.03215	0.1513	0.1186	DLG1/MIR21/KCND3/KCNA5/KCNT2/KCNA3	6
BP	GO:1900409	positive regulation of cellular response to oxidative stress	6/2486	19/18670	0.03215	0.1513	0.1186	TNF/SFPQ/FBXW7/MMP3/MCL1/REST	6
BP	GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	6/2486	19/18670	0.03215	0.1513	0.1186	NOL3/PINK1/SIRT1/NME5/HSPB1/NONO	6
BP	GO:0043367	CD4-positive, alpha-beta T cell differentiation	16/2486	74/18670	0.03232	0.1516	0.1188	SMAD7/CD83/MIR21/ZC3H12A/IRF4/NFKBIZ/HLX/PTGER4/IL23R/BATF/TMEM98/IL2/MTOR/SPN/RC3H1/RSAD2	16
BP	GO:0050710	negative regulation of cytokine secretion	16/2486	74/18670	0.03232	0.1516	0.1188	TNFAIP3/ARG2/TNF/GHRL/GAS6/FCGR2B/CX3CL1/ZC3H12A/FN1/PTGER4/PML/CD34/SSC5D/NR1H4/SYT11/NLRP7	16
BP	GO:1900182	positive regulation of protein localization to nucleus	16/2486	74/18670	0.03232	0.1516	0.1188	RBM22/TGFB1/PARP9/ZC3H12A/SESN2/JUP/CARD10/SMO/GLIS2/CCT8/PLK1/DTX3L/GLI3/IPO5/FLNA/HCLS1	16
BP	GO:0010001	glial cell differentiation	39/2486	218/18670	0.03244	0.1516	0.1188	CLU/C1QA/SIRT2/PPARG/MPP5/WASF3/PARD3/CD9/TNF/DUSP10/TGFB1/TAL1/DAAM2/HES1/CDKN2C/BMP2/NFIB/EGFR/NTRK2/RELA/PTN/LGI4/MXRA8/TMEM98/SMO/GAP43/SOX9/NOTCH1/GLI3/IL1B/TREM2/GPC1/SH3TC2/ROR1/MTOR/LYN/OLIG1/SOX6/EIF2B2	39
BP	GO:1903039	positive regulation of leukocyte cell-cell adhesion	39/2486	218/18670	0.03244	0.1516	0.1188	FAM49B/PDPK1/HLA-DPB1/FADD/ITGA4/TNF/DUSP10/BCL10/TGFB1/IGFBP2/ELANE/CD276/HES1/CD83/MIR21/NFKBIZ/HLX/TRAF6/IL23R/CYLD/VAV1/IGF1/RELA/PDCD1LG2/IL12A/EFNB2/IL2/HAS2/TNFRSF14/GLI3/IL1B/CCL21/THY1/PAK3/CAV1/LYN/PTPRC/CORO1A/DOCK8	39
BP	GO:0071331	cellular response to hexose stimulus	26/2486	135/18670	0.03244	0.1516	0.1188	SRI/LRP5L/TRA2B/SLC2A5/CDK16/GHRL/RAB11FIP5/C2CD2L/GAS6/ERN1/ADRA2A/RAF1/IGF1R/JAGN1/GJB6/IRS2/SLC26A6/POLG/STX4/FKBP1B/PPP3CB/NOX4/UNC13B/NR1H4/LRP5/SIN3A	26
BP	GO:0007097	nuclear migration	7/2486	24/18670	0.03252	0.1516	0.1188	SLC9A3R1/TRIM58/TMEM201/MYH10/SLIT1/DCTN4/SUN2	7
BP	GO:0042832	defense response to protozoan	7/2486	24/18670	0.03252	0.1516	0.1188	IRF8/ARG1/LYST/BATF2/IRF4/BATF/IL12A	7
BP	GO:0051220	cytoplasmic sequestering of protein	7/2486	24/18670	0.03252	0.1516	0.1188	SRI/KEAP1/NFKBIA/NFKBIE/G3BP2/FLNA/DZIP1	7
BP	GO:0099563	modification of synaptic structure	7/2486	24/18670	0.03252	0.1516	0.1188	WASF3/CTTNBP2/WASF1/REST/MYH10/PFN1/STAU1	7
BP	GO:1902547	regulation of cellular response to vascular endothelial growth factor stimulus	7/2486	24/18670	0.03252	0.1516	0.1188	SPRY2/PTP4A3/SMOC2/MYO1C/DCN/ADAMTS12/CCBE1	7
BP	GO:2000178	negative regulation of neural precursor cell proliferation	7/2486	24/18670	0.03252	0.1516	0.1188	SIRT2/LIMS2/TGFB1/PTN/BTG2/WNT5A/SPINT2	7
BP	GO:0045833	negative regulation of lipid metabolic process	19/2486	92/18670	0.03265	0.1521	0.1192	ORMDL1/TNF/SORL1/FBXW7/ERLIN1/ADRA2A/BMP2/APOC1/SIRT1/ERLIN2/CEACAM1/BSCL2/IL1B/REST/WDTC1/ORMDL2/DKK3/NR1H4/LPCAT1	19
BP	GO:0002446	neutrophil mediated immunity	81/2486	499/18670	0.03272	0.1524	0.1194	HBB/SLC15A4/ANXA3/SLPI/CHI3L1/PSMD14/CHIT1/PSMD12/ORM1/SLC2A5/CLEC4C/MME/MMP8/STOM/XRCC6/CD177/CTSG/ARG1/YPEL5/OLFM4/AGA/PGLYRP1/RAB37/FABP5/LTF/VAT1/CD59/PSMD7/ELANE/ACTR10/LCN2/LRMP/CRISP3/ACE/RHOF/DIAPH1/HSP90AA1/FCGR3B/CXCR1/ARHGAP9/CAMP/JAGN1/JUP/AP2A2/C6orf120/RNASE3/UBR4/CEACAM6/COTL1/EEF1A1/PIGR/VCP/HP/CEACAM8/CXCL6/STK10/CEACAM1/MMP9/ITGAL/DDOST/TMC6/CCT8/TSPAN14/PSMB7/HVCN1/SERPINA3/SNAP23/PSMD1/PYGB/CXCL1/CD300A/HSP90AB1/PGRMC1/KCMF1/SLC44A2/PRSS2/PTPRC/PTPRB/CDK13/MMP25/LPCAT1	81
BP	GO:0021545	cranial nerve development	12/2486	51/18670	0.03282	0.1527	0.1197	NAV2/PLXNA3/SLC1A3/HES1/NRP1/ADARB1/SIX1/POU4F1/GLI3/TBX1/EPHB2/HOXA3	12
BP	GO:0055001	muscle cell development	34/2486	186/18670	0.03307	0.1537	0.1205	TMOD1/YY1/CACNA2D2/CAV2/TPM1/HES1/AKAP13/SGCD/NFATC4/LOX/UCHL1/OBSL1/LDB3/IGF1/SIX1/RAMP2/PDGFRA/LMOD1/ALPK3/SMO/PDGFRB/NOTCH1/SHOX2/FLNC/ANK2/SYPL2/CSRP2/SGCB/ALPK2/MTOR/MYH10/DMD/CSRP1/PIN1	34
BP	GO:1903038	negative regulation of leukocyte cell-cell adhesion	25/2486	129/18670	0.03311	0.1538	0.1205	ARG2/ARG1/IRF1/SMAD7/DLG1/TGFB1/PRDX2/FCGR2B/TWSG1/MIR21/ZC3H12A/HLX/CXCL12/ASS1/CEACAM1/PDCD1LG2/IL2/KLF4/TNFRSF14/GLI3/CCL21/GPNMB/CD300A/SPN/RC3H1	25
BP	GO:0034341	response to interferon-gamma	36/2486	199/18670	0.03335	0.1543	0.1209	HLA-DPB1/CAMK2G/PPARG/IRF8/ARG1/SNCA/IRF1/STX8/IFITM3/TRIM21/STXBP1/CX3CL1/MT2A/PARP9/IRF4/CCL13/GCH1/IL23R/JAK1/PML/ASS1/HLA-B/SLC26A6/MID1/RAB7B/MYO1C/IFITM2/RAB12/STX4/CCL21/WNT5A/CCL8/VPS26B/HSP90AB1/CCL18/HLA-A	36
BP	GO:0042026	protein refolding	10/2486	40/18670	0.03346	0.1543	0.1209	PPIL6/PPID/HSP90AA1/NKTR/PPIC/DNAJA4/FKBP1B/DNAJA2/HSPA5/HSPA9	10
BP	GO:0071526	semaphorin-plexin signaling pathway	10/2486	40/18670	0.03346	0.1543	0.1209	SEMA3B/PLXNA3/SEMA3G/NRP1/SEMA4D/SEMA6D/SEMA5B/PLXNA1/FLNA/SEMA3E	10
BP	GO:0035148	tube formation	28/2486	148/18670	0.03359	0.1543	0.1209	ARID1A/IRX2/TWIST1/BCL10/TGFB2/TGFB1/PHACTR4/LUZP1/NFIB/IRX3/TRAF6/SFRP2/LIAS/SIX1/STK4/SEC24B/SOX9/NOTCH1/CTHRC1/SFRP1/WNT5A/PODXL/RPS7/DLC1/PFN1/SPINT2/SETD2/MTHFR	28
BP	GO:0071621	granulocyte chemotaxis	24/2486	123/18670	0.03374	0.1543	0.1209	CXCL5/CSF1/TGFB2/AKIRIN1/CX3CL1/CXCR1/PDE4B/EDN3/THBS4/CCL13/VAV1/RARRES2/ITGA9/DAPK2/CXCL6/PIK3CD/HRH1/IL1B/CCL21/CXCL1/VAV3/CCL8/SLIT2/CCL18	24
BP	GO:0001660	fever generation	4/2486	10/18670	0.03385	0.1543	0.1209	EDNRB/TNF/TNFRSF11A/IL1B	4
BP	GO:0001768	establishment of T cell polarity	4/2486	10/18670	0.03385	0.1543	0.1209	CYP26B1/MYH9/CCL21/DOCK8	4
BP	GO:0006171	cAMP biosynthetic process	4/2486	10/18670	0.03385	0.1543	0.1209	ADCY3/ADCY7/ADCY4/ADCY6	4
BP	GO:0006930	substrate-dependent cell migration, cell extension	4/2486	10/18670	0.03385	0.1543	0.1209	CTTN/NRP1/P2RY12/MYH10	4
BP	GO:0016102	diterpenoid biosynthetic process	4/2486	10/18670	0.03385	0.1543	0.1209	DHRS9/ALDH1A3/ALDH1A2/RBP1	4
BP	GO:0021694	cerebellar Purkinje cell layer formation	4/2486	10/18670	0.03385	0.1543	0.1209	FAIM2/HERC1/LDB1/AGTPBP1	4
BP	GO:0034650	cortisol metabolic process	4/2486	10/18670	0.03385	0.1543	0.1209	CYP11A1/BMP2/REST/DKK3	4
BP	GO:0045876	positive regulation of sister chromatid cohesion	4/2486	10/18670	0.03385	0.1543	0.1209	NIPBL/SMC5/SFPQ/DDX11	4
BP	GO:0048021	regulation of melanin biosynthetic process	4/2486	10/18670	0.03385	0.1543	0.1209	ASIP/SLC24A5/WNT5A/GIPC1	4
BP	GO:0070942	neutrophil mediated cytotoxicity	4/2486	10/18670	0.03385	0.1543	0.1209	CTSG/ARG1/ELANE/CXCL6	4
BP	GO:0071501	cellular response to sterol depletion	4/2486	10/18670	0.03385	0.1543	0.1209	FBXW7/ERLIN1/EIF2A/ERLIN2	4
BP	GO:0086070	SA node cell to atrial cardiac muscle cell communication	4/2486	10/18670	0.03385	0.1543	0.1209	GJA5/KCNA5/ANK2/RYR2	4
BP	GO:0097050	type B pancreatic cell apoptotic process	4/2486	10/18670	0.03385	0.1543	0.1209	EIF2S1/RYR2/CAPN10/WFS1	4
BP	GO:0097278	complement-dependent cytotoxicity	4/2486	10/18670	0.03385	0.1543	0.1209	CR1L/CFH/CD59/HSP90AB1	4
BP	GO:1900122	positive regulation of receptor binding	4/2486	10/18670	0.03385	0.1543	0.1209	BDNF/NRP1/MMP9/HOXA3	4
BP	GO:1904526	regulation of microtubule binding	4/2486	10/18670	0.03385	0.1543	0.1209	GAS8/PPP2CA/MAP2/TTBK2	4
BP	GO:1990253	cellular response to leucine starvation	4/2486	10/18670	0.03385	0.1543	0.1209	EIF2AK4/SESN2/SESN3/MTOR	4
BP	GO:2000035	regulation of stem cell division	4/2486	10/18670	0.03385	0.1543	0.1209	NCOA3/PRDM15/SFRP2/CDK2AP2	4
BP	GO:2000317	negative regulation of T-helper 17 type immune response	4/2486	10/18670	0.03385	0.1543	0.1209	SMAD7/ZC3H12A/IL2/RC3H1	4
BP	GO:2000480	negative regulation of cAMP-dependent protein kinase activity	4/2486	10/18670	0.03385	0.1543	0.1209	PRKAR2A/SIRT1/PKIB/PRKAR2B	4
BP	GO:2001214	positive regulation of vasculogenesis	4/2486	10/18670	0.03385	0.1543	0.1209	RAMP2/CEACAM1/CD34/KDR	4
BP	GO:0010508	positive regulation of autophagy	23/2486	117/18670	0.03434	0.1564	0.1226	VPS13C/EIF2AK4/PINK1/TRIM21/LARP1/FLCN/ZC3H12A/RAB3GAP2/SIRT1/SESN2/SMCR8/FYCO1/WAC/SESN3/PLK3/LRSAM1/RAB12/UVRAG/DCN/KDR/GPSM1/HSPB8/SCOC	23
BP	GO:0010675	regulation of cellular carbohydrate metabolic process	27/2486	142/18670	0.0344	0.1565	0.1227	PMAIP1/GNMT/EP300/SNCA/CD244/PFKFB2/WDR5/SIRT1/SESN2/CBFA2T3/IGF1/GNB3/PTH1R/IGFBP4/IRS2/HRH1/C1QTNF1/FOXK2/KHK/NUPR1/SORBS1/NCOA2/MTOR/MST1/MIDN/PDK4/IGFBP3	27
BP	GO:0045930	negative regulation of mitotic cell cycle	57/2486	338/18670	0.03469	0.1577	0.1236	MUC1/PSMD14/PSMD12/CRADD/SLC9A3R1/CNOT8/CNOT4/EP300/RPS27L/SYF2/APC/TNF/DLG1/GAS1/TGFB1/PSMD7/PSMB5/MTBP/KANK2/CCND1/CTDSPL/CDKN2C/MIR21/FOXC1/MDM4/HECA/EGFR/BCL2L1/PML/FOXN3/BUB1B/CDK2AP2/WNT9A/PLK3/PSMB7/KLF4/PLK1/PSMD1/BTG2/FAP/CDKN2B/PSMD9/GPNMB/FAM107A/CHFR/MAGI2/DUSP1/CNOT7/TTK/TRIAP1/TNKS1BP1/E2F8/PSME1/MUS81/CNOT1/CUL1/ZNF830	57
BP	GO:0072676	lymphocyte migration	22/2486	111/18670	0.03489	0.1585	0.1242	FADD/ITGA4/HSD3B7/CRKL/CH25H/GAS6/CX3CL1/CCL13/ECM1/CXCL12/MSN/STK10/PIK3CD/TNFRSF14/CCL21/WNT5A/CCL8/SPN/GPR15/CCL18/XG/DOCK8	22
BP	GO:0071326	cellular response to monosaccharide stimulus	26/2486	136/18670	0.0352	0.1598	0.1253	SRI/LRP5L/TRA2B/SLC2A5/CDK16/GHRL/RAB11FIP5/C2CD2L/GAS6/ERN1/ADRA2A/RAF1/IGF1R/JAGN1/GJB6/IRS2/SLC26A6/POLG/STX4/FKBP1B/PPP3CB/NOX4/UNC13B/NR1H4/LRP5/SIN3A	26
BP	GO:0001841	neural tube formation	21/2486	105/18670	0.03537	0.1605	0.1258	ARID1A/TWIST1/BCL10/TGFB2/TGFB1/PHACTR4/LUZP1/TRAF6/SFRP2/LIAS/STK4/SEC24B/CTHRC1/SFRP1/WNT5A/RPS7/DLC1/PFN1/SPINT2/SETD2/MTHFR	21
BP	GO:0070227	lymphocyte apoptotic process	15/2486	69/18670	0.03582	0.1616	0.1267	ARG2/FADD/BCL10/CRKL/BTK/P2RX7/MIR17HG/IRS2/IL2/GLI3/WNT5A/LYN/BAK1/TSC22D3/DOCK8	15
BP	GO:0022602	ovulation cycle process	11/2486	46/18670	0.0359	0.1616	0.1267	INHBA/TGFB2/PAM/SIRT1/NOS3/PDGFRA/MMP19/SLIT2/FZD4/HSPA5/ZNF830	11
BP	GO:0032527	protein exit from endoplasmic reticulum	11/2486	46/18670	0.0359	0.1616	0.1267	SEC61B/EDEM1/HSP90B1/SORL1/HERPUD1/DERL1/SEC16A/VCP/UBE2G2/AUP1/SLC35D3	11
BP	GO:0050706	regulation of interleukin-1 beta secretion	11/2486	46/18670	0.0359	0.1616	0.1267	ORM1/TNFAIP3/ARG2/LPL/ZC3H12A/P2RX7/PML/FZD5/NLRP1/WNT5A/NLRP7	11
BP	GO:0097720	calcineurin-mediated signaling	11/2486	46/18670	0.0359	0.1616	0.1267	FHL2/TNF/SPPL3/LMCD1/RCAN2/NFATC4/IGF1/PPP3CB/MTOR/NR5A2/NFATC3	11
BP	GO:1904036	negative regulation of epithelial cell apoptotic process	11/2486	46/18670	0.0359	0.1616	0.1267	PDPK1/TNFAIP3/GAS6/ANGPTL4/RAMP2/PAK4/NUPR1/TEK/MTOR/KDR/WFS1	11
BP	GO:1990928	response to amino acid starvation	11/2486	46/18670	0.0359	0.1616	0.1267	RRAGA/MAP1LC3A/DEPDC5/EIF2AK4/EIF2S1/LARP1/SESN2/EIF2A/MAP3K5/SESN3/MTOR	11
BP	GO:0001881	receptor recycling	9/2486	35/18670	0.03598	0.1616	0.1267	SNCA/ARFGEF2/SORL1/PLEKHJ1/AP1AR/TBC1D16/RAMP3/CAMLG/INPP5F	9
BP	GO:0002701	negative regulation of production of molecular mediator of immune response	9/2486	35/18670	0.03598	0.1616	0.1267	PARP3/ARG1/TNF/SMAD7/TGFB2/TGFB1/FCGR2B/IL13RA2/IL33	9
BP	GO:0033144	negative regulation of intracellular steroid hormone receptor signaling pathway	9/2486	35/18670	0.03598	0.1616	0.1267	HEYL/PHB2/KANK2/ZBTB7A/DAB2/SIRT1/SFRP1/PER1/CNOT1	9
BP	GO:0045622	regulation of T-helper cell differentiation	9/2486	35/18670	0.03598	0.1616	0.1267	SMAD7/MIR21/ZC3H12A/IRF4/NFKBIZ/HLX/IL23R/IL2/RC3H1	9
BP	GO:0060251	regulation of glial cell proliferation	9/2486	35/18670	0.03598	0.1616	0.1267	TNF/CREB1/HES1/PTN/NOTCH1/IL1B/MTOR/LYN/ADCYAP1	9
BP	GO:0098751	bone cell development	9/2486	35/18670	0.03598	0.1616	0.1267	SH2B3/EP300/WASF2/LTF/TAL1/FBXW7/FLI1/NOTCH2/FBN1	9
BP	GO:1901385	regulation of voltage-gated calcium channel activity	9/2486	35/18670	0.03598	0.1616	0.1267	SRI/FGF14/CACNB3/PDE4B/STAC/GPR35/STAC2/AHNAK/DMD	9
BP	GO:0006903	vesicle targeting	19/2486	93/18670	0.03609	0.1619	0.1269	TRAPPC10/SCFD1/PEF1/CNIH3/CD59/LRMP/CLASP2/WDR11/TFG/SEC16A/F8/AP1AR/BET1/SEC24B/SNAP23/GOSR1/TBC1D23/ARFGAP2/CLASP1	19
BP	GO:0036473	cell death in response to oxidative stress	19/2486	93/18670	0.03609	0.1619	0.1269	NOL3/SFPQ/PINK1/FBXW7/STK24/MIR21/PYCR1/SIRT1/NME5/HSPB1/PML/MAP3K5/MMP3/MELK/MCL1/DIABLO/PDCD10/REST/NONO	19
BP	GO:0045844	positive regulation of striated muscle tissue development	18/2486	87/18670	0.03628	0.1624	0.1273	TBX5/TGFB1/CREB1/CYP26B1/IGF1/MIR17HG/EFNB2/CDON/MTM1/TBX2/NOTCH1/SHOX2/YAP1/GPC1/ZFPM2/TBX1/MTOR/PIN1	18
BP	GO:0048636	positive regulation of muscle organ development	18/2486	87/18670	0.03628	0.1624	0.1273	TBX5/TGFB1/CREB1/CYP26B1/IGF1/MIR17HG/EFNB2/CDON/MTM1/TBX2/NOTCH1/SHOX2/YAP1/GPC1/ZFPM2/TBX1/MTOR/PIN1	18
BP	GO:0021766	hippocampus development	17/2486	81/18670	0.03632	0.1624	0.1273	ANXA3/FGF13/PLXNA3/SCT/CRKL/KDM6B/SMO/SLC32A1/MFSD2A/KCNA1/GLI3/BTG2/CDK5R1/EMX2/EZH1/KIF14/NCOA1	17
BP	GO:0110110	positive regulation of animal organ morphogenesis	17/2486	81/18670	0.03632	0.1624	0.1273	ACVR1/TNFAIP3/CSF1/TWIST1/TGFB2/TGFB1/SPRY1/BMP2/PTN/SIX1/HOXB7/SMO/FRS2/SOX9/CD34/NOTCH1/HOXA11	17
BP	GO:0002285	lymphocyte activation involved in immune response	33/2486	181/18670	0.03649	0.1631	0.1278	CD1C/MSH6/PARP3/EIF2AK4/PGLYRP1/SMAD7/CD244/TGFB1/FCGR2B/MIR21/ZC3H12A/IRF4/NFKBIZ/HLX/EXO1/PTGER4/EXOSC3/IL23R/BATF/MFNG/CEACAM1/ITGAL/TMEM98/IL2/GAPT/NOTCH2/MTOR/SPN/RC3H1/PTPRC/CORO1A/DOCK11/RNF8	33
BP	GO:0048284	organelle fusion	24/2486	124/18670	0.03674	0.164	0.1285	STX2/MFF/SNCA/CAV2/VAT1/STX16/STX8/LRMP/TGFBRAP1/STXBP1/BET1/RAB7B/SNAP23/GOSR1/STX4/UVRAG/VAV3/BAK1/BNIP1/SAMD9L/RAB8A/STXBP6/CORO1A/PRRT2	24
BP	GO:0051209	release of sequestered calcium ion into cytosol	24/2486	124/18670	0.03674	0.164	0.1285	SRI/PDPK1/ITPR1/SNCA/MCOLN3/NOL3/TGFB1/DIAPH1/CX3CL1/DDIT3/P2RX7/PLCB2/PLCB1/APLNR/IBTK/FKBP1B/CCL21/THY1/ANK2/RYR2/LYN/DMD/PTPRC/CORO1A	24
BP	GO:0034284	response to monosaccharide	37/2486	207/18670	0.03684	0.1643	0.1287	SRI/LRP5L/TRA2B/SLC2A5/SPARC/CDK16/LPL/GHRL/TGFB1/TRH/PFKFB2/RAB11FIP5/C2CD2L/GAS6/ERN1/ADRA2A/RAF1/IGF1R/SESN2/JAGN1/GJB6/IRS2/SLC26A6/KHK/POLG/STX4/FKBP1B/ANGPT2/PPP3CB/NOX4/COL6A2/ITGA2/UNC13B/NR1H4/LRP5/SIN3A/EIF2B2	37
BP	GO:0031960	response to corticosteroid	30/2486	162/18670	0.03707	0.1652	0.1295	ANXA3/FOSB/SPARC/ARG1/TNF/CDO1/TGFB1/IGFBP2/TRH/ZFP36/AKAP13/CCND1/PAM/ALPL/FOS/EGFR/HSD11B2/STC1/ASS1/CPN1/AQP1/NOTCH1/CPS1/NR3C1/REST/FAM107A/DUSP1/SLIT2/ADCYAP1/FIBIN	30
BP	GO:0044344	cellular response to fibroblast growth factor stimulus	27/2486	143/18670	0.03721	0.1657	0.1299	SPRY2/DSTYK/SNCA/GALNT3/CRKL/HNRNPM/SPRY1/ZFP36/FGF18/SPRY4/SMOC2/POLR2G/FLRT2/CBL/SULF1/FRS2/CREB3L1/CPS1/SFRP1/GPC1/WNT5A/TBX1/POSTN/KL/CDC5L/POLR2D/HYAL1	27
BP	GO:0120032	regulation of plasma membrane bounded cell projection assembly	32/2486	175/18670	0.03759	0.1673	0.1311	EPS8/APC/WASF2/AKIRIN1/AGRN/PLEK2/ANLN/NRP1/P2RY12/CYLD/FNBP1L/P2RX7/CEP135/DPYSL3/GAP43/IFT140/CDKL1/KLF5/CCL21/NCKAP1/ADAMTS16/MIR214/DZIP1/PODXL/ARPC2/CAV1/SLIT2/MTOR/PFN1/CDC42EP5/DOCK11/EPS8L1	32
BP	GO:0006457	protein folding	40/2486	227/18670	0.03786	0.1683	0.1319	CLU/DNLZ/PPIL6/BAG4/PPIL1/HSP90B1/DNAJA1/PDIA3/RGS7/FKBP4/AHSP/PPID/ERP29/HSP90AA1/UBXN1/DNAJB14/DNAJC10/HSPB1/DERL1/NKTR/GRPEL1/GNB3/VCP/PPIC/DNAJC24/DNAJA4/CCT8/FKBP1B/HSPB6/HSP90AB1/PRKCSH/DNAJA2/PFDN1/ENGASE/PDCD5/WFS1/HSPA5/CRYAB/LTBP4/HSPA9	40
BP	GO:0051783	regulation of nuclear division	34/2486	188/18670	0.0379	0.1684	0.132	SIRT2/APC/NIPBL/SMC5/CAV2/TGFB1/MTBP/PHB2/ANLN/CDKN1C/SMPD3/GPR3/CHMP1B/EDN3/CCDC8/HECW2/OBSL1/IGF1/EGF/BUB1B/PLCB1/PLK1/PDGFRB/UBE2C/IL1B/WNT5A/MSX1/DUSP1/TTK/CDK13/LRP5/MKI67/NEK2/PIN1	34
BP	GO:0001938	positive regulation of endothelial cell proliferation	22/2486	112/18670	0.03815	0.1691	0.1326	ITGB3/PDPK1/ITGA4/ARG1/CAV2/JUN/GHRL/VEGFC/NRP1/MIR21/BMP2/EGFL7/SIRT1/THBS4/ECM1/CXCL12/AGTR1/APLNR/TEK/WNT5A/MTOR/KDR	22
BP	GO:1903510	mucopolysaccharide metabolic process	22/2486	112/18670	0.03815	0.1691	0.1326	IDS/CHST1/B4GALT2/TGFB1/SMPD3/EGF/CHST3/BGN/HAS2/IL1B/LYVE1/HAS3/DCN/HAS1/ACAN/OGN/CSPG4/ITIH2/FMOD/PRELP/B4GALT4/HYAL1	22
BP	GO:1903828	negative regulation of cellular protein localization	22/2486	112/18670	0.03815	0.1691	0.1326	BAG4/DNAJA1/TGFB1/FLCN/FBXO4/DAB2/BCL2L1/ANKRD13A/TTBK2/TMEM98/DCLK1/OTUD7B/LRRC15/RANGAP1/UBE2G2/DCLK3/PKDCC/BARD1/SIN3A/MRAP2/LZTS2/GDI1	22
BP	GO:0010743	regulation of macrophage derived foam cell differentiation	8/2486	30/18670	0.03831	0.1696	0.1329	ITGB3/PPARG/NFKBIA/CSF1/LPL/MSR1/AGTR1/PLA2G2A	8
BP	GO:0048384	retinoic acid receptor signaling pathway	8/2486	30/18670	0.03831	0.1696	0.1329	CRKL/RXRB/CYP26B1/PML/PRAME/ALDH1A2/TBX1/CNOT1	8
BP	GO:0097237	cellular response to toxic substance	43/2486	247/18670	0.03856	0.1706	0.1337	HBB/HBD/MAP1LC3A/TNFAIP3/ARG1/ADCY7/TNF/FXN/PINK1/LCN2/PRDX2/CYGB/KDM6B/PXDN/NXN/ABCG2/HBM/MIR21/SMPD3/ZC3H12A/PYCR1/DDX11/SIRT1/SESN2/LOXHD1/GCH1/GSTT1/NOS3/MAP3K5/RELA/HP/AQP1/KLF4/GPX8/HBQ1/CPS1/PDCD10/MSX1/PCGF2/KDR/SOD3/AXL/NQO1	43
BP	GO:0044774	mitotic DNA integrity checkpoint	21/2486	106/18670	0.03877	0.1714	0.1344	MUC1/CRADD/CNOT8/CNOT4/EP300/RPS27L/SYF2/CCND1/MIR21/MDM4/PML/FOXN3/PLK3/BTG2/CNOT7/TRIAP1/TNKS1BP1/E2F8/MUS81/CNOT1/ZNF830	21
BP	GO:0030837	negative regulation of actin filament polymerization	13/2486	58/18670	0.03891	0.1714	0.1344	EPS8/TMOD1/MYADM/AVIL/PFN4/LMOD1/CAPZA1/TMSB4Y/TMSB15A/MIR214/SLIT2/KANK3/PFN1	13
BP	GO:0051058	negative regulation of small GTPase mediated signal transduction	13/2486	58/18670	0.03891	0.1714	0.1344	SPRY2/SCAI/TGFB2/SPRY1/FLCN/SPRY4/ITGA3/SLIT2/DLC1/TNFAIP1/CGNL1/MAPKAP1/EPHB2	13
BP	GO:0061900	glial cell activation	13/2486	58/18670	0.03891	0.1714	0.1344	CLU/C1QA/MMP8/SNCA/TNF/JUN/CX3CL1/EGFR/SMO/IL1B/IL33/TREM2/PTPRC	13
BP	GO:1902807	negative regulation of cell cycle G1/S phase transition	25/2486	131/18670	0.03904	0.1714	0.1344	MUC1/CRADD/CNOT8/CNOT4/EP300/RPS27L/KANK2/CCND1/CTDSPL/CDKN2C/MIR21/MDM4/PML/CDK2AP2/PLK3/KLF4/BTG2/CDKN2B/GPNMB/FAM107A/CNOT7/TRIAP1/TNKS1BP1/E2F8/CNOT1	25
BP	GO:0010821	regulation of mitochondrion organization	33/2486	182/18670	0.03907	0.1714	0.1344	CLU/ABLIM3/CTTN/PMAIP1/VPS13C/BAG4/MFF/SLC25A5/SQSTM1/FXN/NOL3/VAT1/PINK1/MOAP1/ARIH2/PDE2A/FBXW7/FLCN/BCL2L1/IGF1/YWHAZ/MMP9/BMF/TREM2/FZD5/UBE2D3/DCN/TP53BP2/TRIAP1/BAK1/KDR/PDCD5/CIDEB	33
BP	GO:0034122	negative regulation of toll-like receptor signaling pathway	10/2486	41/18670	0.03916	0.1714	0.1344	PDPK1/TNFAIP3/OTUD4/LILRA4/IRF4/RAB7B/CD300LF/TLR9/CD300A/LYN	10
BP	GO:0035136	forelimb morphogenesis	10/2486	41/18670	0.03916	0.1714	0.1344	NIPBL/TBX5/TWIST1/WNT9A/SHOX2/HOXA11/ALDH1A2/MSX1/HOXA9/HOXD9	10
BP	GO:0061028	establishment of endothelial barrier	10/2486	41/18670	0.03916	0.1714	0.1344	CLDN5/MYADM/PROC/TNF/PDE2A/RAPGEF3/MSN/IL1B/TJP1/CDH5	10
BP	GO:1903053	regulation of extracellular matrix organization	10/2486	41/18670	0.03916	0.1714	0.1344	TGFB1/CLASP2/PDPN/PHLDB2/HAS2/SOX9/NOTCH1/FAP/DDR2/CLASP1	10
BP	GO:1901215	negative regulation of neuron death	37/2486	208/18670	0.03926	0.1714	0.1344	NTF3/PDPK1/FAIM2/BDNF/CSF1/SNCA/JUN/PINK1/SORL1/HYOU1/CREB1/NRP1/CRLF1/STXBP1/CX3CL1/REL/NFATC4/SIRT1/BCL2L1/NTRK2/SIX1/CBL/POU4F1/CD34/BTG2/NES/GPNMB/REST/NONO/NR4A2/HSP90AB1/SET/WFS1/CORO1A/AXL/KIF14/PIN1	37
BP	GO:0007351	tripartite regional subdivision	5/2486	15/18670	0.03954	0.1714	0.1344	PCSK6/HOXD8/FRS2/FZD5/WNT5A	5
BP	GO:0008595	anterior/posterior axis specification, embryo	5/2486	15/18670	0.03954	0.1714	0.1344	PCSK6/HOXD8/FRS2/FZD5/WNT5A	5
BP	GO:0015671	oxygen transport	5/2486	15/18670	0.03954	0.1714	0.1344	HBB/HBD/CYGB/HBM/HBQ1	5
BP	GO:0032239	regulation of nucleobase-containing compound transport	5/2486	15/18670	0.03954	0.1714	0.1344	AKAP8L/DHX9/NUP153/KHDRBS1/SETD2	5
BP	GO:0034111	negative regulation of homotypic cell-cell adhesion	5/2486	15/18670	0.03954	0.1714	0.1344	SH2B3/CD9/CEACAM1/C1QTNF1/ABAT	5
BP	GO:0035067	negative regulation of histone acetylation	5/2486	15/18670	0.03954	0.1714	0.1344	SNCA/TWIST1/SIRT1/SET/SIN3A	5
BP	GO:0042762	regulation of sulfur metabolic process	5/2486	15/18670	0.03954	0.1714	0.1344	PDPR/SNCA/MIR21/PDP1/PDK4	5
BP	GO:0042921	glucocorticoid receptor signaling pathway	5/2486	15/18670	0.03954	0.1714	0.1344	RBM14/ARID1A/NR3C1/PER1/NCOA6	5
BP	GO:0043249	erythrocyte maturation	5/2486	15/18670	0.03954	0.1714	0.1344	EPB42/L3MBTL3/TRIM58/TAL1/ZBTB7A	5
BP	GO:0046851	negative regulation of bone remodeling	5/2486	15/18670	0.03954	0.1714	0.1344	INPP5D/TNFAIP3/TMEM119/P2RX7/SFRP1	5
BP	GO:0051127	positive regulation of actin nucleation	5/2486	15/18670	0.03954	0.1714	0.1344	WHAMM/WASF1/FCHSD2/NCKAP1/MAGEL2	5
BP	GO:0051883	killing of cells in other organism involved in symbiotic interaction	5/2486	15/18670	0.03954	0.1714	0.1344	CTSG/ARG1/ELANE/CAMP/CXCL6	5
BP	GO:0060339	negative regulation of type I interferon-mediated signaling pathway	5/2486	15/18670	0.03954	0.1714	0.1344	YTHDF2/SAMHD1/MIR21/YTHDF3/CNOT7	5
BP	GO:0060766	negative regulation of androgen receptor signaling pathway	5/2486	15/18670	0.03954	0.1714	0.1344	HEYL/ZBTB7A/DAB2/SIRT1/SFRP1	5
BP	GO:0090177	establishment of planar polarity involved in neural tube closure	5/2486	15/18670	0.03954	0.1714	0.1344	SFRP2/SEC24B/CTHRC1/SFRP1/WNT5A	5
BP	GO:0090197	positive regulation of chemokine secretion	5/2486	15/18670	0.03954	0.1714	0.1344	MBP/TNF/LPL/IL33/POSTN	5
BP	GO:1900119	positive regulation of execution phase of apoptosis	5/2486	15/18670	0.03954	0.1714	0.1344	SIRT2/ZC3H12A/FAP/TP53BP2/DLC1	5
BP	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway	5/2486	15/18670	0.03954	0.1714	0.1344	PLEKHA4/DAB2/SFRP2/RSPO3/SFRP1	5
BP	GO:0030032	lamellipodium assembly	14/2486	64/18670	0.03972	0.1719	0.1348	ABLIM3/PTPRO/WASF3/WASF2/AKIRIN1/P2RY12/ARHGEF7/WHAMM/NCKAP1/VAV3/MIR214/ARPC2/SLIT2/MTOR	14
BP	GO:0035773	insulin secretion involved in cellular response to glucose stimulus	14/2486	64/18670	0.03972	0.1719	0.1348	SRI/LRP5L/CDK16/GHRL/RAB11FIP5/C2CD2L/ADRA2A/RAF1/JAGN1/STX4/FKBP1B/PPP3CB/NR1H4/LRP5	14
BP	GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	60/2486	361/18670	0.03985	0.1722	0.135	CLU/FAM49B/C1QB/C1QA/CD1C/C1QC/MSH6/INPP5D/TNFAIP3/FADD/PARP3/ARG1/NFKB2/TNF/SMAD7/DLG1/BCL10/IL1R1/TGFB1/C2/FBXO38/FCGR2B/MIR21/ZC3H12A/CD1B/IRF4/NFKBIZ/HLX/EXO1/BTK/SERPING1/EXOSC3/TRAF6/IL23R/BATF/P2RX7/HLA-B/CEACAM1/C1RL/IL13RA2/IL12A/TMEM98/IL2/C1R/EMP2/GAPT/IL1B/IL33/PPP3CB/FZD5/POU2F2/MTOR/C1S/CFI/SPN/RC3H1/PTPRC/RSAD2/HLA-A/RNF8	60
BP	GO:0001562	response to protozoan	7/2486	25/18670	0.04013	0.1722	0.135	IRF8/ARG1/LYST/BATF2/IRF4/BATF/IL12A	7
BP	GO:0007026	negative regulation of microtubule depolymerization	7/2486	25/18670	0.04013	0.1722	0.135	FGF13/NAV3/APC/CLASP2/TTBK2/MID1/CLASP1	7
BP	GO:0008211	glucocorticoid metabolic process	7/2486	25/18670	0.04013	0.1722	0.135	CYP11A1/BMP2/CYP21A2/HSD11B2/HSD11B1/REST/DKK3	7
BP	GO:0019430	removal of superoxide radicals	7/2486	25/18670	0.04013	0.1722	0.135	TNF/PRDX2/MIR21/GCH1/NOS3/SOD3/NQO1	7
BP	GO:0034110	regulation of homotypic cell-cell adhesion	7/2486	25/18670	0.04013	0.1722	0.135	SH2B3/CD9/PDPN/CEACAM1/C1QTNF1/LYN/ABAT	7
BP	GO:0050901	leukocyte tethering or rolling	7/2486	25/18670	0.04013	0.1722	0.135	ITGA4/TNF/ELANE/SELP/CXCL12/CCL21/SPN	7
BP	GO:0060444	branching involved in mammary gland duct morphogenesis	7/2486	25/18670	0.04013	0.1722	0.135	LRP5L/CSF1/TGFB1/PHB2/PML/WNT5A/LRP5	7
BP	GO:0060561	apoptotic process involved in morphogenesis	7/2486	25/18670	0.04013	0.1722	0.135	TGFB2/JAG2/FOXC1/NOTCH1/FZD5/BAK1/CRYAB	7
BP	GO:0072677	eosinophil migration	7/2486	25/18670	0.04013	0.1722	0.135	CX3CL1/PTGER4/CCL13/DAPK2/HRH1/CCL8/CD300A	7
BP	GO:1903306	negative regulation of regulated secretory pathway	7/2486	25/18670	0.04013	0.1722	0.135	FCGR2B/ADRA2A/CEACAM1/IL13RA2/NOTCH1/REST/CD300A	7
BP	GO:0043470	regulation of carbohydrate catabolic process	18/2486	88/18670	0.04014	0.1722	0.135	NUP93/PFKFB2/ZBTB7A/NUP50/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/RAE1/NUP188/NUP160/NUP54/NUP214/NUP155/NUPR1/SLC2A6/PRKAG2	18
BP	GO:1901863	positive regulation of muscle tissue development	18/2486	88/18670	0.04014	0.1722	0.135	TBX5/TGFB1/CREB1/CYP26B1/IGF1/MIR17HG/EFNB2/CDON/MTM1/TBX2/NOTCH1/SHOX2/YAP1/GPC1/ZFPM2/TBX1/MTOR/PIN1	18
BP	GO:0001936	regulation of endothelial cell proliferation	32/2486	176/18670	0.04028	0.1727	0.1353	ITGB3/PDPK1/PPARG/ITGA4/SPARC/ARG1/CAV2/TNF/FLT1/JUN/GHRL/VEGFC/NRP1/MIR21/BMP2/EGFL7/SIRT1/THBS4/ECM1/CXCL12/VASH1/NR2F2/AGTR1/SULF1/APLNR/TEK/ALDH1A2/PDCD10/WNT5A/CAV1/MTOR/KDR	32
BP	GO:0070374	positive regulation of ERK1 and ERK2 cascade	38/2486	215/18670	0.04044	0.1733	0.1358	SPRY2/CHI3L1/DSTYK/TNF/FLT1/JUN/CRKL/TGFB1/PHB2/PLA2G5/NRP1/GAS6/FBXW7/CX3CL1/MIR21/FGF18/BMP2/CCL13/EGFR/NPNT/PDGFRA/TNFRSF11A/RAMP3/PDGFRB/NOTCH1/NOTCH2/PLA2G2A/TEK/CCL21/TREM2/GPNMB/NOX4/CCL8/IL26/KDR/ADCYAP1/PTPRC/CCL18	38
BP	GO:0048002	antigen processing and presentation of peptide antigen	34/2486	189/18670	0.0405	0.1734	0.1359	PSMD14/PSMD12/ITGB5/HLA-DPB1/KIF26A/ARF1/DYNC1I1/PSMD7/PDIA3/PSMB5/ACTR10/ACE/FCGR2B/TAPBPL/TRAF6/KIF4A/AP2A2/HLA-B/SEC24B/IDE/PSMB7/KIF2C/CAPZA1/SNAP23/PSMD1/TREM2/PSMD9/CTSF/DYNLL2/PSME1/AP1S3/DCTN4/HLA-A/KLC1	34
BP	GO:0006612	protein targeting to membrane	36/2486	202/18670	0.04054	0.1735	0.136	SEC62/RPS27/RPS28/SEC61B/STOM/MFF/PARD3/RPS15/UBA52/CACNB3/RPS26/RPLP1/VPS37A/RPL28/RPS3A/RTP4/SSR1/RPL10/RPL29/TRAM1L1/VPS37B/RPS8/RPS4Y1/RPS2/RPL39/RPS10/MYO1C/RPL6/CDK5R1/RPL14/RPS7/HSPA5/SRP54/RPL9/RPL15/GDI1	36
BP	GO:0043369	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment	6/2486	20/18670	0.0409	0.174	0.1364	IRF4/IL23R/CYLD/BATF/MTOR/SPN	6
BP	GO:0048670	regulation of collateral sprouting	6/2486	20/18670	0.0409	0.174	0.1364	FGF13/BDNF/RND2/SPP1/SEMA4D/ULK2	6
BP	GO:0060008	Sertoli cell differentiation	6/2486	20/18670	0.0409	0.174	0.1364	RAB13/SAFB2/ARID4A/SOX9/NUP210L/FLNA	6
BP	GO:0070262	peptidyl-serine dephosphorylation	6/2486	20/18670	0.0409	0.174	0.1364	PPTC7/PPP1R15A/PPP1R15B/PPP2CA/PPM1F/DUSP1	6
BP	GO:0086014	atrial cardiac muscle cell action potential	6/2486	20/18670	0.0409	0.174	0.1364	GJA5/KCNA5/NUP155/ANK2/FLNA/RYR2	6
BP	GO:0086026	atrial cardiac muscle cell to AV node cell signaling	6/2486	20/18670	0.0409	0.174	0.1364	GJA5/KCNA5/NUP155/ANK2/FLNA/RYR2	6
BP	GO:0086066	atrial cardiac muscle cell to AV node cell communication	6/2486	20/18670	0.0409	0.174	0.1364	GJA5/KCNA5/NUP155/ANK2/FLNA/RYR2	6
BP	GO:1900151	regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	6/2486	20/18670	0.0409	0.174	0.1364	TNRC6B/ZFP36/POLR2G/BTG2/CNOT7/CNOT1	6
BP	GO:0009895	negative regulation of catabolic process	52/2486	308/18670	0.04128	0.1755	0.1376	SIRT2/RRAGA/GABARAPL2/SCFD1/HERC1/SNCA/TNF/DHX9/PINK1/SORL1/ZFP36/ADRA2A/LARP1/MIR21/UBXN1/SMARCC1/APOC1/USP7/MDM4/EGFR/SMCR8/PML/CBFA2T3/RELA/HP/WAC/TIMP3/BMF/LRIG2/BANP/FOXK2/YBX1/MCL1/BSCL2/MTM1/NUPR1/LAPTM4B/CAMLG/IL1B/TREM2/TIMP4/UBE2G2/FLNA/AZIN1/HSP90AB1/RPS7/IL10RA/MTOR/TAF1/MYCBP2/GIPC1/PIN1	52
BP	GO:0014911	positive regulation of smooth muscle cell migration	11/2486	47/18670	0.04143	0.1757	0.1377	SSH1/NRP1/MIR21/IGF1/SEMA6D/IGFBP5/PDGFRB/HAS2/NOX4/POSTN/ITGA2	11
BP	GO:0030574	collagen catabolic process	11/2486	47/18670	0.04143	0.1757	0.1377	ADAMTS2/MMP8/MMP1/MRC2/ADAMTS14/MMP3/MMP9/MMP19/FAP/PRSS2/MMP25	11
BP	GO:0045646	regulation of erythrocyte differentiation	11/2486	47/18670	0.04143	0.1757	0.1377	KLF13/INPP5D/INHBA/GATA1/TRIM58/TAL1/LDB1/ZFP36/ACVR2A/LYN/HSPA9	11
BP	GO:0070169	positive regulation of biomineral tissue development	11/2486	47/18670	0.04143	0.1757	0.1377	ACVR1/TMEM119/LTF/TGFB1/BMP2/FBN2/P2RX7/ACVR2A/PTN/PKDCC/KL	11
BP	GO:0042119	neutrophil activation	80/2486	498/18670	0.04148	0.1758	0.1378	HBB/SLC15A4/ANXA3/SLPI/CHI3L1/PSMD14/CHIT1/PSMD12/ORM1/SLC2A5/CLEC4C/MME/MMP8/STOM/XRCC6/CD177/CTSG/ARG1/YPEL5/OLFM4/AGA/PGLYRP1/RAB37/FABP5/LTF/VAT1/CD59/PSMD7/ELANE/ACTR10/LCN2/LRMP/CRISP3/RHOF/FCGR2B/DIAPH1/HSP90AA1/FCGR3B/CXCR1/ARHGAP9/CAMP/JUP/AP2A2/C6orf120/RNASE3/UBR4/CEACAM6/COTL1/EEF1A1/PIGR/VCP/HP/CEACAM8/CXCL6/STK10/CEACAM1/MMP9/ITGAL/DDOST/TMC6/CCT8/TSPAN14/PSMB7/HVCN1/SERPINA3/SNAP23/PSMD1/PYGB/CXCL1/CD300A/HSP90AB1/PGRMC1/KCMF1/SLC44A2/PRSS2/PTPRC/PTPRB/CDK13/MMP25/LPCAT1	80
BP	GO:0006699	bile acid biosynthetic process	9/2486	36/18670	0.0425	0.1793	0.1405	OSBP/OSBPL6/HSD3B7/CH25H/SIRT1/OSBPL9/AKR1D1/CYP39A1/NR1H4	9
BP	GO:0030224	monocyte differentiation	9/2486	36/18670	0.0425	0.1793	0.1405	INPP5D/PPARG/CSF1/JUN/HOXA7/IFI16/SP3/PIR/MYH9	9
BP	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	9/2486	36/18670	0.0425	0.1793	0.1405	ITGB3/GRB10/PRKCB/FLT1/VEGFC/FGF18/MMRN2/IL1B/FZD4	9
BP	GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	9/2486	36/18670	0.0425	0.1793	0.1405	SPRY2/DSTYK/SPRY1/SPRY4/SMOC2/SULF1/CREB3L1/GPC1/WNT5A	9
BP	GO:1901099	negative regulation of signal transduction in absence of ligand	9/2486	36/18670	0.0425	0.1793	0.1405	GATA1/TNF/STRADB/PRDX2/CX3CL1/BCL2L1/MCL1/IFI6/IL1B	9
BP	GO:1903131	mononuclear cell differentiation	9/2486	36/18670	0.0425	0.1793	0.1405	INPP5D/PPARG/CSF1/JUN/HOXA7/IFI16/SP3/PIR/MYH9	9
BP	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	9/2486	36/18670	0.0425	0.1793	0.1405	GATA1/TNF/STRADB/PRDX2/CX3CL1/BCL2L1/MCL1/IFI6/IL1B	9
BP	GO:0043312	neutrophil degranulation	78/2486	485/18670	0.04267	0.1798	0.141	HBB/SLC15A4/ANXA3/SLPI/CHI3L1/PSMD14/CHIT1/PSMD12/ORM1/SLC2A5/CLEC4C/MME/MMP8/STOM/XRCC6/CD177/CTSG/ARG1/YPEL5/OLFM4/AGA/PGLYRP1/RAB37/FABP5/LTF/VAT1/CD59/PSMD7/ELANE/ACTR10/LCN2/LRMP/CRISP3/RHOF/DIAPH1/HSP90AA1/FCGR3B/CXCR1/ARHGAP9/CAMP/JUP/AP2A2/C6orf120/RNASE3/UBR4/CEACAM6/COTL1/EEF1A1/PIGR/VCP/HP/CEACAM8/STK10/CEACAM1/MMP9/ITGAL/DDOST/TMC6/CCT8/TSPAN14/PSMB7/HVCN1/SERPINA3/SNAP23/PSMD1/PYGB/CXCL1/CD300A/HSP90AB1/PGRMC1/KCMF1/SLC44A2/PRSS2/PTPRC/PTPRB/CDK13/MMP25/LPCAT1	78
BP	GO:1901990	regulation of mitotic cell cycle phase transition	72/2486	444/18670	0.04274	0.1799	0.141	MUC1/SIRT2/PSMD14/PSMD12/CRADD/CNOT8/CNOT4/EP300/RPS27L/SYF2/APC/PBX1/TGFB1/PSMD7/PSMB5/MTBP/PHB2/ANLN/KANK2/CDKN1C/CCND1/HSP90AA1/CTDSPL/CDKN2C/CEP192/MIR21/TPX2/MDM4/EGFR/HECW2/PML/CEP135/FOXN3/HAUS8/BUB1B/PLCB1/CDK2AP2/ODF2/CDC45/KCNA5/ANAPC10/PLK3/PSMB7/KLF4/PLK1/UBE2C/PSMD1/BTG2/CDKN2B/PSMD9/GPNMB/MIR214/FAM107A/HAUS2/NDE1/DUSP1/CNOT7/SSNA1/TTK/CLASP1/TRIAP1/TNKS1BP1/E2F8/PSME1/PRKAR2B/HYAL1/SIN3A/KIF14/NEK2/CNOT1/CUL1/ZNF830	72
BP	GO:0007088	regulation of mitotic nuclear division	30/2486	164/18670	0.04277	0.1799	0.141	SIRT2/APC/NIPBL/SMC5/CAV2/TGFB1/MTBP/PHB2/ANLN/CDKN1C/SMPD3/CHMP1B/EDN3/CCDC8/HECW2/OBSL1/IGF1/EGF/BUB1B/PLK1/PDGFRB/UBE2C/IL1B/DUSP1/TTK/CDK13/LRP5/MKI67/NEK2/PIN1	30
BP	GO:0035821	modification of morphology or physiology of other organism	30/2486	164/18670	0.04277	0.1799	0.141	RRAGA/IFI27/SLPI/STOM/CTSG/ARG1/EP300/EIF2AK4/PGLYRP1/CAV2/JUN/LTF/TGFB1/ELANE/TNIP1/CHD1/ZC3H12A/KPNA1/CAMP/CCL13/BCL2L1/P2RX7/PABPN1/CXCL6/KPNA3/AQP1/SERPINB9/REST/CCL8/KPNA4	30
BP	GO:0043331	response to dsRNA	12/2486	53/18670	0.04301	0.1803	0.1413	PMAIP1/NFKBIA/DHX9/DDX21/PQBP1/IFIH1/P2RX7/IFIT1/COLEC12/CAV1/RFTN2/ZCCHC3	12
BP	GO:0045661	regulation of myoblast differentiation	12/2486	53/18670	0.04301	0.1803	0.1413	TNF/AKIRIN1/TGFB1/BOC/DDIT3/MAP3K5/PLCB1/CDON/SOX9/NOTCH1/CMTM5/IGFBP3	12
BP	GO:0045840	positive regulation of mitotic nuclear division	12/2486	53/18670	0.04301	0.1803	0.1413	NIPBL/SMC5/TGFB1/PHB2/SMPD3/EDN3/IGF1/EGF/PDGFRB/UBE2C/IL1B/LRP5	12
BP	GO:0050704	regulation of interleukin-1 secretion	12/2486	53/18670	0.04301	0.1803	0.1413	ORM1/TNFAIP3/ARG2/LPL/GAS6/ZC3H12A/P2RX7/PML/FZD5/NLRP1/WNT5A/NLRP7	12
BP	GO:0070228	regulation of lymphocyte apoptotic process	12/2486	53/18670	0.04301	0.1803	0.1413	ARG2/FADD/BCL10/BTK/P2RX7/MIR17HG/IRS2/IL2/WNT5A/LYN/TSC22D3/DOCK8	12
BP	GO:0060491	regulation of cell projection assembly	32/2486	177/18670	0.04311	0.1805	0.1415	EPS8/APC/WASF2/AKIRIN1/AGRN/PLEK2/ANLN/NRP1/P2RY12/CYLD/FNBP1L/P2RX7/CEP135/DPYSL3/GAP43/IFT140/CDKL1/KLF5/CCL21/NCKAP1/ADAMTS16/MIR214/DZIP1/PODXL/ARPC2/CAV1/SLIT2/MTOR/PFN1/CDC42EP5/DOCK11/EPS8L1	32
BP	GO:0032611	interleukin-1 beta production	20/2486	101/18670	0.04312	0.1805	0.1415	SUCNR1/ORM1/TNFAIP3/ARG2/LPL/GHRL/IFI16/CX3CL1/ZC3H12A/HSPB1/P2RX7/PML/IGF1/ACP5/IL1B/TREM2/FZD5/NLRP1/WNT5A/NLRP7	20
BP	GO:0051283	negative regulation of sequestering of calcium ion	24/2486	126/18670	0.04333	0.1811	0.1419	SRI/PDPK1/ITPR1/SNCA/MCOLN3/NOL3/TGFB1/DIAPH1/CX3CL1/DDIT3/P2RX7/PLCB2/PLCB1/APLNR/IBTK/FKBP1B/CCL21/THY1/ANK2/RYR2/LYN/DMD/PTPRC/CORO1A	24
BP	GO:0006874	cellular calcium ion homeostasis	74/2486	458/18670	0.04334	0.1811	0.1419	SRI/SLC24A3/PDPK1/ITPR1/EDNRB/GTF2I/ATP7B/PRKCB/HSP90B1/SNCA/MCOLN3/NOL3/SPPL3/GHRL/TGFB1/LPAR6/ELANE/HERPUD1/CACNB3/TACR1/DIAPH1/FAM155A/CX3CL1/CXCR1/BDKRB2/GPR4/PTGER4/EDN3/DDIT3/CCL13/STC1/P2RX7/LPAR4/MCHR1/GPR35/PML/CXCL12/SLC24A5/PLCB2/SLC25A27/PTH1R/PTGFR/PLCB1/PDGFRA/KCNA5/AGTR1/C1QTNF1/IL2/RAMP3/APLNR/KCNK3/CIB2/IBTK/FKBP1B/CCL21/THY1/ANK2/SYPL2/OXTR/WNT5A/P2RY8/CCL8/RYR2/CDH5/CAV1/STC2/LYN/BAK1/C19orf12/ADCYAP1/DMD/WFS1/PTPRC/CORO1A	74
BP	GO:0000077	DNA damage checkpoint	27/2486	145/18670	0.04335	0.1811	0.1419	MUC1/CRADD/CNOT8/CNOT4/EP300/RPS27L/SYF2/EIF2AK4/CCND1/MIR21/FBXO4/USP28/MDM4/PML/FOXN3/WAC/PLK3/PLK1/BTG2/CNOT7/TRIAP1/TNKS1BP1/E2F8/MUS81/CDC5L/CNOT1/ZNF830	27
BP	GO:0007249	I-kappaB kinase/NF-kappaB signaling	46/2486	269/18670	0.04349	0.1816	0.1423	PDPK1/TNFAIP3/ZFAND6/FADD/NFKBIA/PRKCB/SQSTM1/TNF/BCL10/LTF/USP10/PINK1/AKAP13/UBA52/TNIP1/SLC20A1/MAP3K14/CX3CL1/ZC3H12A/TFG/DDX21/BTK/REL/SIRT1/TRAF6/ECM1/HSPB1/RELA/PLEKHG5/TSPAN6/PPM1A/IFIT5/OTUD7B/IL1B/CCL21/UBC/WNT5A/FLNA/TLR9/ROR1/MAP3K3/SLC44A2/PER1/NR1H4/ALPK1/APOL3	46
BP	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	19/2486	95/18670	0.04375	0.1824	0.143	PSMD14/PSMD12/FBXO33/PSMD7/PSMB5/FBXO38/FBXW7/FBXO4/WWTR1/FBXL13/FBXL8/PSMB7/PSMD1/PSMD9/SKP2/FBXL14/PSME1/KIF14/CUL1	19
BP	GO:0097711	ciliary basal body-plasma membrane docking	19/2486	95/18670	0.04375	0.1824	0.143	B9D1/HSP90AA1/CEP192/B9D2/CEP135/HAUS8/ODF2/SCLT1/NPHP1/TTBK2/PLK1/C2CD3/HAUS2/NDE1/SSNA1/CLASP1/TMEM67/PRKAR2B/NEK2	19
BP	GO:0051604	protein maturation	65/2486	397/18670	0.04398	0.1832	0.1436	CLU/PROS1/C1QB/C1QA/C1QC/ADAMTS2/MME/CR1L/CFH/CTSG/FADD/TBC1D10A/EP300/ATP7B/FXN/NOL3/SPPL3/CD59/GAS1/NAA16/C2/SORL1/IFI16/CFB/ACE/PCSK6/FKRP/NAA30/CREBBP/SERPING1/ASPH/P2RX7/SERPINH1/CFHR2/CPE/CPN1/C1RL/SPCS1/PLAT/TMEM98/TSPAN14/C1R/CPXM1/GLI3/MYH9/IL1B/FKBP1B/C2CD3/SPCS3/NAA25/GLRX5/RNF139/C1S/BAK1/CFI/WFS1/ENPEP/A2M/SPON1/ASPRV1/NAA15/CLEC3B/CCBE1/NLRP7/CIDEB	65
BP	GO:0010518	positive regulation of phospholipase activity	13/2486	59/18670	0.04405	0.1832	0.1436	NTF3/ARHGAP6/PDPK1/BDNF/FLT1/PLA2G5/P2RY12/EGFR/NTRK2/PLCB2/PDGFRA/AGTR1/PDGFRB	13
BP	GO:0021885	forebrain cell migration	13/2486	59/18670	0.04405	0.1832	0.1436	FGF13/LHX6/NRP1/P2RY12/EGFR/CXCL12/GLI3/LAMB1/CDK5R1/EMX2/SLIT2/SUN2/AXL	13
BP	GO:2000351	regulation of endothelial cell apoptotic process	13/2486	59/18670	0.04405	0.1832	0.1436	PDPK1/TNFAIP3/ITGA4/TNF/GAS6/ANGPTL4/COL18A1/ECSCR/RAMP2/PAK4/TEK/CD248/KDR	13
BP	GO:0097306	cellular response to alcohol	18/2486	89/18670	0.04428	0.184	0.1442	ADCY3/GRAMD1B/PPARG/INHBA/ADCY7/LARP1/PTGER4/JUP/ADCY6/PTGFR/AKR1C2/SMO/KLF4/SFRP1/HMGCS1/AKAP8/GRAMD1C/TNC	18
BP	GO:0050854	regulation of antigen receptor-mediated signaling pathway	14/2486	65/18670	0.04465	0.1851	0.1451	LPXN/PRKCB/BCL10/ELF2/FCGR2B/CYLD/RELA/CEACAM1/THY1/CD300A/CMTM3/LYN/RC3H1/PTPRC	14
BP	GO:0060389	pathway-restricted SMAD protein phosphorylation	14/2486	65/18670	0.04465	0.1851	0.1451	ACVR1/INHBA/SMAD7/TGFB2/TGFB1/TWSG1/BMP2/DAB2/ACVR2A/INHBE/BMP8A/RBPMS/TTK/PIN1	14
BP	GO:0072678	T cell migration	14/2486	65/18670	0.04465	0.1851	0.1451	FADD/ITGA4/CRKL/ECM1/CXCL12/MSN/PIK3CD/TNFRSF14/CCL21/WNT5A/SPN/GPR15/XG/DOCK8	14
BP	GO:0006970	response to osmotic stress	17/2486	83/18670	0.04467	0.1851	0.1451	PDPK1/XRCC6/TNF/TSC22D2/NOLC1/LRRC8A/BDKRB2/EGFR/KCNMA1/PLK3/AQP1/RCSD1/EFHD1/LRRC8E/HSP90AB1/ITGA2/TSC22D3	17
BP	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	16/2486	77/18670	0.0449	0.1858	0.1456	LSM4/CNOT8/CNOT4/LSM7/TNRC6B/ZFP36/DCP2/EXOSC3/POLR2G/BTG2/CNOT7/TNKS1BP1/POLR2D/RC3H1/DDX6/CNOT1	16
BP	GO:0048332	mesoderm morphogenesis	16/2486	77/18670	0.0449	0.1858	0.1456	ITGB3/ACVR1/INHBA/TAL1/KDM6B/TWSG1/SMAD1/FOXC1/SFRP2/ITGA3/KLF4/HOXA11/WNT5A/SIX2/ITGA2/SETD2	16
BP	GO:0015749	monosaccharide transmembrane transport	22/2486	114/18670	0.04533	0.1872	0.1468	GRB10/SLC2A5/CLIP3/RTN2/PRKCB/TNF/FABP5/SESN2/SLC2A8/IGF1/SLC45A1/ADIPOR2/SLC25A27/IRS2/SLC2A6/PRKAG2/IL1B/SORBS1/SLC2A10/SLC2A12/SLC23A1/CAPN10	22
BP	GO:0000187	activation of MAPK activity	28/2486	152/18670	0.04536	0.1872	0.1468	IQGAP3/NTF3/MAPK11/TNF/GHRL/CRKL/PRDX2/UBA52/ERN1/ERP29/BMP2/TRAF6/MAP3K2/P2RX7/MAP3K5/IGF1/EGF/FRS2/IL1B/UBC/WNT5A/PAK3/MAPKAPK5/CSPG4/MADD/GHR/PDE6G/PTPRC	28
BP	GO:0030902	hindbrain development	28/2486	152/18670	0.04536	0.1872	0.1468	FAIM2/HERC1/B4GALT2/CRKL/LDB1/HES1/FCGR2B/SMAD1/FOXC1/NFIB/EGF/PTN/AGTPBP1/TTBK2/SEC24B/SMO/POU4F1/ALDH1A2/CDK5R1/FLNA/NLGN4X/DLC1/MYH10/FZD4/HSPA5/KIF14/ABAT/NCOA1	28
BP	GO:0032675	regulation of interleukin-6 production	28/2486	152/18670	0.04536	0.1872	0.1468	ORM1/INPP5D/MMP8/TNFAIP3/MBP/TNF/TWIST1/LPL/GHRL/DHX9/GAS6/CX3CL1/ZC3H12A/TRAF6/IFIH1/P2RX7/RAB7B/AFAP1L2/IL1B/IL17D/IL33/TREM2/WNT5A/TLR9/TBC1D23/ADCYAP1/NR1H4/SYT11	28
BP	GO:0006509	membrane protein ectodomain proteolysis	10/2486	42/18670	0.04548	0.1874	0.1469	TNF/ADRA2A/P2RX7/TIMP3/LRIG2/MYH9/IL1B/TIMP4/RBMX/SH3D19	10
BP	GO:0010470	regulation of gastrulation	10/2486	42/18670	0.04548	0.1874	0.1469	MBP/MYADM/CLASP2/SFRP2/TGIF2/PHLDB2/KLF4/COL5A1/CLASP1/COL5A2	10
BP	GO:0015701	bicarbonate transport	10/2486	42/18670	0.04548	0.1874	0.1469	HBB/SLC4A1/CA1/SLC26A10/CA4/SLC26A6/CA14/AQP1/CA12/SLC26A8	10
BP	GO:0006605	protein targeting	70/2486	432/18670	0.0458	0.1874	0.1469	CLU/ABLIM3/SEC62/RPS27/RPS28/TIMM23/DNLZ/VPS13C/SEC61B/STOM/ZFAND6/TOMM20/BAG4/TRAK1/MFF/PARD3/GNPTAB/TIMM44/PINK1/RPS15/TIMM10/SORL1/ARIH2/UBA52/CACNB3/FBXW7/RPS26/RPLP1/VPS37A/RPL28/RPS3A/HSP90AA1/RTP4/SSR1/RPL10/RPL29/SLC25A6/TRAM1L1/GRPEL1/YWHAZ/VPS37B/RPS8/RPS4Y1/RPS2/NUP54/RPL39/RPS10/SPCS1/IDE/MYO1C/RPL6/LTBP2/FZD5/CDK5R1/SPCS3/UBC/UBE2D3/CRAT/RPL14/RPS7/PDCD5/HSPA5/AP1S3/AP4E1/SRP54/GIPC1/RPL9/RPL15/HMGCL/GDI1	70
BP	GO:0006482	protein demethylation	8/2486	31/18670	0.04581	0.1874	0.1469	UTY/KDM5D/KDM6B/HSF4/KDM2A/JMJD6/JMJD1C/JARID2	8
BP	GO:0008214	protein dealkylation	8/2486	31/18670	0.04581	0.1874	0.1469	UTY/KDM5D/KDM6B/HSF4/KDM2A/JMJD6/JMJD1C/JARID2	8
BP	GO:0010762	regulation of fibroblast migration	8/2486	31/18670	0.04581	0.1874	0.1469	BAG4/C5orf30/TGFB1/CYGB/ARHGEF7/PAK3/HAS1/DDR2	8
BP	GO:0033198	response to ATP	8/2486	31/18670	0.04581	0.1874	0.1469	HSP90B1/SSH1/P2RY12/P2RX7/P2RY2/CIB2/IL1B/TAF1	8
BP	GO:0035767	endothelial cell chemotaxis	8/2486	31/18670	0.04581	0.1874	0.1469	RAB13/NRP1/FGF18/HSPB1/SMOC2/PLEKHG5/NOTCH1/KDR	8
BP	GO:0045880	positive regulation of smoothened signaling pathway	8/2486	31/18670	0.04581	0.1874	0.1469	GAS8/EVC/WNT9A/SMO/PRRX1/SHOX2/SFRP1/INTU	8
BP	GO:0070306	lens fiber cell differentiation	8/2486	31/18670	0.04581	0.1874	0.1469	MAF/TMOD1/WNT5B/TGFB1/CDKN1C/SKIL/BFSP1/FRS2	8
BP	GO:1902253	regulation of intrinsic apoptotic signaling pathway by p53 class mediator	8/2486	31/18670	0.04581	0.1874	0.1469	MUC1/MIR21/BDKRB2/SIRT1/HNRNPK/MSX1/RPS7/TRIAP1	8
BP	GO:1903393	positive regulation of adherens junction organization	8/2486	31/18670	0.04581	0.1874	0.1469	NRP1/COL16A1/TEK/SFRP1/THY1/LIMS1/PPM1F/KDR	8
BP	GO:2000406	positive regulation of T cell migration	8/2486	31/18670	0.04581	0.1874	0.1469	FADD/ITGA4/CXCL12/TNFRSF14/CCL21/WNT5A/SPN/DOCK8	8
BP	GO:0034764	positive regulation of transmembrane transport	36/2486	204/18670	0.04596	0.1878	0.1472	SRI/SLC9A3R1/PDPK1/ARF1/CLIP3/SNCA/ATP1B2/PINK1/FGF14/CACNB3/CX3CL1/MIR21/EDN3/STAC/P2RX7/IGF1/ADIPOR2/STAC2/IRS2/SLC26A6/RAMP3/FXYD1/APLNR/KCNA1/SORBS1/THY1/TREM2/ANK2/FLNA/AZIN1/RYR2/CAPN10/DMD/ARC/EPHB2/SHANK3	36
BP	GO:0010950	positive regulation of endopeptidase activity	32/2486	178/18670	0.04609	0.1883	0.1476	PSMD14/PMAIP1/CRADD/MBP/FADD/PPARG/TBC1D10A/CASP4/RPS27L/SNCA/TNF/BCL10/IFI16/MIR21/SIRT1/ASPH/SFRP2/PML/MAP3K5/VCP/PRR7/DIABLO/NLRP1/REST/PPM1F/LYN/DLC1/BAK1/PDCD5/PSME1/ANP32B/CIDEB	32
BP	GO:1904659	glucose transmembrane transport	21/2486	108/18670	0.04628	0.1889	0.1481	GRB10/SLC2A5/CLIP3/RTN2/PRKCB/TNF/FABP5/SESN2/SLC2A8/IGF1/SLC45A1/ADIPOR2/SLC25A27/IRS2/SLC2A6/PRKAG2/IL1B/SORBS1/SLC2A10/SLC2A12/CAPN10	21
BP	GO:0008038	neuron recognition	11/2486	48/18670	0.04753	0.1907	0.1494	NRCAM/NEXN/NRP1/YWHAZ/ROBO4/GAP43/CDK5R1/NDN/IGSF9/NCAM2/EPHB2	11
BP	GO:0030865	cortical cytoskeleton organization	11/2486	48/18670	0.04753	0.1907	0.1494	CIT/RTKN/PPP2R3C/RAB13/TNF/DLG1/ANLN/FMNL1/EHD2/NCKAP1/EPB41L1	11
BP	GO:0061014	positive regulation of mRNA catabolic process	11/2486	48/18670	0.04753	0.1907	0.1494	CNOT8/YTHDF2/TNRC6B/ZFP36/ZC3H12A/POLR2G/BTG2/YTHDF3/CNOT7/RC3H1/CNOT1	11
BP	GO:2000059	negative regulation of ubiquitin-dependent protein catabolic process	11/2486	48/18670	0.04753	0.1907	0.1494	UBXN1/SMARCC1/USP7/PML/WAC/MTM1/CAMLG/HSP90AB1/RPS7/TAF1/GIPC1	11
BP	GO:0000050	urea cycle	4/2486	11/18670	0.04772	0.1907	0.1494	ARG2/ARG1/ASS1/CPS1	4
BP	GO:0001731	formation of translation preinitiation complex	4/2486	11/18670	0.04772	0.1907	0.1494	EIF5/EIF4B/DENR/EIF4H	4
BP	GO:0001767	establishment of lymphocyte polarity	4/2486	11/18670	0.04772	0.1907	0.1494	CYP26B1/MYH9/CCL21/DOCK8	4
BP	GO:0001778	plasma membrane repair	4/2486	11/18670	0.04772	0.1907	0.1494	SYTL4/MYH9/MYH10/SYT11	4
BP	GO:0001821	histamine secretion	4/2486	11/18670	0.04772	0.1907	0.1494	BTK/SNAP23/LYN/ADCYAP1	4
BP	GO:0002638	negative regulation of immunoglobulin production	4/2486	11/18670	0.04772	0.1907	0.1494	PARP3/FCGR2B/IL13RA2/IL33	4
BP	GO:0003093	regulation of glomerular filtration	4/2486	11/18670	0.04772	0.1907	0.1494	PTPRO/GAS6/GJA5/EMP2	4
BP	GO:0003174	mitral valve development	4/2486	11/18670	0.04772	0.1907	0.1494	ACVR1/TWIST1/GJA5/NOTCH1	4
BP	GO:0003264	regulation of cardioblast proliferation	4/2486	11/18670	0.04772	0.1907	0.1494	TBX5/HES1/SIX1/NOTCH1	4
BP	GO:0021561	facial nerve development	4/2486	11/18670	0.04772	0.1907	0.1494	PLXNA3/NRP1/ADARB1/SIX1	4
BP	GO:0021610	facial nerve morphogenesis	4/2486	11/18670	0.04772	0.1907	0.1494	PLXNA3/NRP1/ADARB1/SIX1	4
BP	GO:0021670	lateral ventricle development	4/2486	11/18670	0.04772	0.1907	0.1494	AQP1/TSKU/DNAH5/MYH10	4
BP	GO:0031652	positive regulation of heat generation	4/2486	11/18670	0.04772	0.1907	0.1494	TNF/TNFRSF11A/IL1B/ABAT	4
BP	GO:0042482	positive regulation of odontogenesis	4/2486	11/18670	0.04772	0.1907	0.1494	CSF1/TGFB1/BMP2/CD34	4
BP	GO:0044793	negative regulation by host of viral process	4/2486	11/18670	0.04772	0.1907	0.1494	EIF2AK4/LTF/ZC3H12A/CCL8	4
BP	GO:0045919	positive regulation of cytolysis	4/2486	11/18670	0.04772	0.1907	0.1494	RRAGA/PGLYRP1/P2RX7/CFHR2	4
BP	GO:0046501	protoporphyrinogen IX metabolic process	4/2486	11/18670	0.04772	0.1907	0.1494	ALAS2/UROD/IREB2/ALAS1	4
BP	GO:0051013	microtubule severing	4/2486	11/18670	0.04772	0.1907	0.1494	KATNAL2/KATNAL1/KATNA1/LZTS2	4
BP	GO:0098887	neurotransmitter receptor transport, endosome to postsynaptic membrane	4/2486	11/18670	0.04772	0.1907	0.1494	GRIP1/GRIP2/GRASP/RAB8A	4
BP	GO:0099639	neurotransmitter receptor transport, endosome to plasma membrane	4/2486	11/18670	0.04772	0.1907	0.1494	GRIP1/GRIP2/GRASP/RAB8A	4
BP	GO:1900102	negative regulation of endoplasmic reticulum unfolded protein response	4/2486	11/18670	0.04772	0.1907	0.1494	PPP1R15A/PPP1R15B/WFS1/HSPA5	4
BP	GO:1900115	extracellular regulation of signal transduction	4/2486	11/18670	0.04772	0.1907	0.1494	LTBP1/FBN2/GREM2/FBN1	4
BP	GO:1900116	extracellular negative regulation of signal transduction	4/2486	11/18670	0.04772	0.1907	0.1494	LTBP1/FBN2/GREM2/FBN1	4
BP	GO:1901201	regulation of extracellular matrix assembly	4/2486	11/18670	0.04772	0.1907	0.1494	TGFB1/HAS2/SOX9/NOTCH1	4
BP	GO:1903977	positive regulation of glial cell migration	4/2486	11/18670	0.04772	0.1907	0.1494	CSF1/CRKL/P2RY12/TREM2	4
BP	GO:1904396	regulation of neuromuscular junction development	4/2486	11/18670	0.04772	0.1907	0.1494	CRKL/AGRN/PTN/SIX1	4
BP	GO:1905668	positive regulation of protein localization to endosome	4/2486	11/18670	0.04772	0.1907	0.1494	SORL1/MSN/EGF/DTX3L	4
BP	GO:2000392	regulation of lamellipodium morphogenesis	4/2486	11/18670	0.04772	0.1907	0.1494	ARHGEF7/PDPN/ENPP2/RREB1	4
BP	GO:2001204	regulation of osteoclast development	4/2486	11/18670	0.04772	0.1907	0.1494	LTF/FBXW7/NOTCH2/FBN1	4
BP	GO:0008585	female gonad development	19/2486	96/18670	0.048	0.1914	0.15	INHBA/TAF4/TIPARP/FOXC1/SIRT1/BCL2L1/NOS3/PDGFRA/MMP19/NUPR1/SFRP1/ZFPM2/SLIT2/ADCYAP1/FZD4/HSPA5/EIF2B2/LHX8/ZNF830	19
BP	GO:0030516	regulation of axon extension	19/2486	96/18670	0.048	0.1914	0.15	NRCAM/CTTN/SEMA3B/RNF6/PLXNA3/SEMA3G/NRP1/L1CAM/FN1/SEMA4D/CXCL12/SEMA6D/SEMA5B/MAP2/CDK5R1/WNT5A/SEMA3E/SIN3A/GDI1	19
BP	GO:0097553	calcium ion transmembrane import into cytosol	26/2486	140/18670	0.04803	0.1914	0.15	SRI/PDPK1/ITPR1/SNCA/MCOLN3/NOL3/TGFB1/DIAPH1/FAM155A/CX3CL1/DDIT3/P2RX7/PLCB2/PLCB1/RAMP3/APLNR/IBTK/FKBP1B/CCL21/THY1/ANK2/RYR2/LYN/DMD/PTPRC/CORO1A	26
BP	GO:0002283	neutrophil activation involved in immune response	78/2486	488/18670	0.04803	0.1914	0.15	HBB/SLC15A4/ANXA3/SLPI/CHI3L1/PSMD14/CHIT1/PSMD12/ORM1/SLC2A5/CLEC4C/MME/MMP8/STOM/XRCC6/CD177/CTSG/ARG1/YPEL5/OLFM4/AGA/PGLYRP1/RAB37/FABP5/LTF/VAT1/CD59/PSMD7/ELANE/ACTR10/LCN2/LRMP/CRISP3/RHOF/DIAPH1/HSP90AA1/FCGR3B/CXCR1/ARHGAP9/CAMP/JUP/AP2A2/C6orf120/RNASE3/UBR4/CEACAM6/COTL1/EEF1A1/PIGR/VCP/HP/CEACAM8/STK10/CEACAM1/MMP9/ITGAL/DDOST/TMC6/CCT8/TSPAN14/PSMB7/HVCN1/SERPINA3/SNAP23/PSMD1/PYGB/CXCL1/CD300A/HSP90AB1/PGRMC1/KCMF1/SLC44A2/PRSS2/PTPRC/PTPRB/CDK13/MMP25/LPCAT1	78
BP	GO:0043618	regulation of transcription from RNA polymerase II promoter in response to stress	23/2486	121/18670	0.04811	0.1916	0.1502	MUC1/SIRT2/PSMD14/PSMD12/EP300/JUN/PSMD7/PSMB5/UBA52/CREBBP/HSF4/SESN2/DDIT3/PSMB7/CREB3L1/NOTCH1/PSMD1/PSMD9/UBC/TAF1/PSME1/HSPA5/SIN3A	23
BP	GO:0071356	cellular response to tumor necrosis factor	49/2486	291/18670	0.04825	0.1921	0.1505	CHI3L1/PSMD14/PSMD12/TNFAIP3/ZFAND6/CASP4/BAG4/CLIP3/SPATA2/NFKBIA/TNF/NOL3/DHX9/PSMD7/PSMB5/LCN2/ZFP36/HIPK1/GAS6/MAP3K14/CX3CL1/SMPD3/ZC3H12A/PLVAP/SIRT1/CCL13/CYLD/NPNT/MAP3K5/RELA/ASS1/TNFRSF11A/CCDC3/PSMB7/HAS2/TNFRSF14/PSMD1/CCL21/SFRP1/PSMD9/LIMS1/CCL8/MADD/POSTN/PSME1/ADAMTS12/NR1H4/CCL18/HYAL1	49
BP	GO:0050807	regulation of synapse organization	38/2486	218/18670	0.04845	0.1927	0.151	NRCAM/PTPRO/SPARC/BDNF/SNCA/TNF/GHRL/CRKL/CUX2/SSH1/AGRN/CTTNBP2/FCGR2B/GPC4/TPBG/NFATC4/NTRK2/LRRN1/SEMA4D/YWHAZ/PTN/VCP/SIX1/FLRT2/CRIPT/SRPX2/GAP43/CDK5R1/OXTR/WNT5A/PAK3/IGSF9/IL10RA/ARC/SLIT1/EPHB2/ARHGEF15/SHANK3	38
BP	GO:0032651	regulation of interleukin-1 beta production	18/2486	90/18670	0.04872	0.1931	0.1513	ORM1/TNFAIP3/ARG2/LPL/GHRL/IFI16/CX3CL1/ZC3H12A/HSPB1/P2RX7/PML/IGF1/ACP5/TREM2/FZD5/NLRP1/WNT5A/NLRP7	18
BP	GO:0071674	mononuclear cell migration	18/2486	90/18670	0.04872	0.1931	0.1513	PTPRO/CSF1/TNF/FLT1/AKIRIN1/TGFB1/CX3CL1/CCL13/RARRES2/CXCL12/PLCB1/TNFRSF11A/CCL21/CCL8/DUSP1/SLIT2/LYN/CCL18	18
BP	GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin	7/2486	26/18670	0.04882	0.1931	0.1513	SUCNR1/MME/CTSG/ACE/GJA5/AGTR1/ENPEP	7
BP	GO:0021591	ventricular system development	7/2486	26/18670	0.04882	0.1931	0.1513	NME5/SEMA6D/AQP1/TSKU/DNAH5/MYH10/ANP32B	7
BP	GO:0034114	regulation of heterotypic cell-cell adhesion	7/2486	26/18670	0.04882	0.1931	0.1513	MBP/MYADM/TNF/CEACAM6/KLF4/IL1B/THY1	7
BP	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway	7/2486	26/18670	0.04882	0.1931	0.1513	IGFBP2/BMP2/IGF1/IGFBP4/IGFBP5/CILP/IGFBP3	7
BP	GO:0051788	response to misfolded protein	7/2486	26/18670	0.04882	0.1931	0.1513	CLU/SDF2L1/KLHL15/DNAJB14/DERL1/VCP/SDF2	7
BP	GO:0060740	prostate gland epithelium morphogenesis	7/2486	26/18670	0.04882	0.1931	0.1513	SULF1/FRS2/SOX9/NOTCH1/SFRP1/WNT5A/TNC	7
BP	GO:1900120	regulation of receptor binding	7/2486	26/18670	0.04882	0.1931	0.1513	BDNF/NRP1/LOX/PTPRF/MMP9/GREM2/HOXA3	7
BP	GO:0006096	glycolytic process	22/2486	115/18670	0.04927	0.1946	0.1525	SLC4A1/NUP93/PFKFB2/DHTKD1/ZBTB7A/NUP50/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/RAE1/NUP188/NUP160/NUP54/NUP214/NUP155/FOXK2/NUPR1/SLC2A6/PRKAG2/PFKP	22
BP	GO:0046660	female sex differentiation	22/2486	115/18670	0.04927	0.1946	0.1525	INHBA/TAF4/TIPARP/FOXC1/SIRT1/BCL2L1/NOS3/PDGFRA/MMP19/NUPR1/SFRP1/ZFPM2/WNT5A/SLIT2/BAK1/ADCYAP1/FZD4/HSPA5/AXL/EIF2B2/LHX8/ZNF830	22
BP	GO:0002718	regulation of cytokine production involved in immune response	17/2486	84/18670	0.04933	0.1946	0.1525	ARG1/TRIM6/TNF/SMAD7/BCL10/TGFB2/IL1R1/TGFB1/DDX21/BTK/TRAF6/TNFRSF14/IL1B/FZD5/WNT5A/TRIL/RSAD2	17
BP	GO:0045445	myoblast differentiation	17/2486	84/18670	0.04933	0.1946	0.1525	PLEKHM3/MBNL1/TNF/AKIRIN1/TGFB1/BOC/DDIT3/MAP3K5/IGF1/PLCB1/CDON/SOX9/TBX2/NOTCH1/REST/CMTM5/IGFBP3	17
BP	GO:0032273	positive regulation of protein polymerization	25/2486	134/18670	0.04938	0.1947	0.1526	RHOBTB1/CTTN/BAG4/NAV3/ARF1/DLG1/PINK1/HSP90AA1/AP1AR/NIN/LMOD1/WHAMM/WASF1/MYO1C/FCHSD2/CCL21/CDK5R1/NCKAP1/ARPC2/MTOR/CLASP1/PFN1/CDC42EP5/CORO1A/MAGEL2	25
BP	GO:0008589	regulation of smoothened signaling pathway	16/2486	78/18670	0.04977	0.1953	0.1531	GAS8/EVC/GAS1/CREBBP/WDR11/WNT9A/SMO/GLIS2/PRRX1/IFT140/SHOX2/GLI3/SFRP1/C2CD3/IFT81/INTU	16
BP	GO:0033143	regulation of intracellular steroid hormone receptor signaling pathway	16/2486	78/18670	0.04977	0.1953	0.1531	EP300/HEYL/RNF6/KDM5D/SAFB2/PHB2/KANK2/ZBTB7A/DAB2/SIRT1/YAP1/SFRP1/SKP2/TAF1/PER1/CNOT1	16
BP	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	9/2486	37/18670	0.04977	0.1953	0.1531	CNOT8/CNOT4/TNRC6B/ZFP36/POLR2G/BTG2/CNOT7/TNKS1BP1/CNOT1	9
BP	GO:0034405	response to fluid shear stress	9/2486	37/18670	0.04977	0.1953	0.1531	SMAD7/TGFB1/NOS3/P2RX7/MTSS1/ASS1/KLF4/PDGFRB/HAS2	9
BP	GO:0042307	positive regulation of protein import into nucleus	9/2486	37/18670	0.04977	0.1953	0.1531	RBM22/TGFB1/ZC3H12A/JUP/SMO/GLI3/IPO5/FLNA/HCLS1	9
BP	GO:0046006	regulation of activated T cell proliferation	9/2486	37/18670	0.04977	0.1953	0.1531	FADD/ARG1/IGFBP2/MIR21/IL23R/IGF1/PDCD1LG2/IL2/RC3H1	9
BP	GO:2000249	regulation of actin cytoskeleton reorganization	9/2486	37/18670	0.04977	0.1953	0.1531	NTF3/TGFB1/NRP1/RAPGEF3/PDGFRA/NOTCH2/TEK/HCLS1/SEMA3E	9
BP	GO:0090150	establishment of protein localization to membrane	55/2486	332/18670	0.0498	0.1953	0.1531	SEC62/RPS27/PMAIP1/RPS28/SEC61B/GRIP1/STOM/MFF/PARD3/RPS15/TIMM10/MOAP1/UBA52/CACNB3/RPS26/RPLP1/VPS37A/RPL28/RPS3A/HSP90AA1/RAB3GAP2/RTP4/GRIP2/SSR1/RPL10/EGFR/SEC16A/RPL29/TRAM1L1/YWHAZ/BBS1/VPS37B/RPS8/RPS4Y1/UBL4A/RPS2/GRASP/RPL39/BMF/RPS10/MYO1C/RPL6/CDK5R1/SYS1/TP53BP2/PKDCC/RPL14/RPS7/PDCD5/RAB8A/HSPA5/SRP54/RPL9/RPL15/GDI1	55
BP	GO:0015800	acidic amino acid transport	14/2486	66/18670	0.04999	0.1957	0.1534	SNCA/SLC1A3/TRH/STXBP1/LRRC8A/CLN8/NTRK2/P2RX7/SLC1A1/LRRC8E/UNC13B/GIPC1/SLC6A1/ABAT	14
BP	GO:0046888	negative regulation of hormone secretion	14/2486	66/18670	0.04999	0.1957	0.1534	SYTL4/INHBA/GHRL/RAB11FIP1/RAB11FIP5/ADRA2A/JAGN1/BMP8A/IL1B/FKBP1B/SFRP1/PSMD9/REST/MIDN	14
BP	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	14/2486	66/18670	0.04999	0.1957	0.1534	ITGB3/EPS8/GRIP1/CPT1C/DLG1/DLG2/GRIP2/GPC4/GPC6/GRASP/EFNB2/DNM1/ARC/RAB8A	14
BP	GO:0035019	somatic stem cell population maintenance	15/2486	72/18670	0.05001	0.1957	0.1534	PBX1/LDB1/HES1/DPPA4/NANOG/RAF1/POLR2G/KLF10/KLF4/SOX9/YAP1/SFRP1/REST/SIX2/POLR2D	15
BP	GO:0006914	autophagy	79/2486	496/18670	0.05015	0.1959	0.1536	CLU/SIRT2/RRAGA/CTTN/GABARAPL2/SCFD1/VPS13C/MAP1LC3A/ITPR1/TOMM20/HERC1/IRF8/EP300/ATP6V1E1/EIF2AK4/SNCA/SQSTM1/USP10/PINK1/TRIM21/IFI16/TECPR1/FBXW7/ERN1/LARP1/VPS37A/ATP6V0A2/HSP90AA1/FLCN/ZC3H12A/RAB3GAP2/CHMP6/SIRT1/SESN2/DDIT3/FNBP1L/SMCR8/HSPB1/UCHL1/ULK2/DAPK2/EEF1A1/FYCO1/VCP/ATG4B/WAC/MTMR14/VPS37B/BMF/SESN3/TMEM150C/FUNDC1/PLK3/FOXK2/MCL1/MTM1/NUPR1/LRSAM1/PRKAG2/RAB12/TREM2/SPATA18/ACBD5/FZD5/CDK5R1/UVRAG/DCN/USP33/VPS26B/IL10RA/MTOR/C19orf12/KDR/DYNLL2/GPSM1/RAB8A/TMEM74/HSPB8/SCOC	79
BP	GO:0061919	process utilizing autophagic mechanism	79/2486	496/18670	0.05015	0.1959	0.1536	CLU/SIRT2/RRAGA/CTTN/GABARAPL2/SCFD1/VPS13C/MAP1LC3A/ITPR1/TOMM20/HERC1/IRF8/EP300/ATP6V1E1/EIF2AK4/SNCA/SQSTM1/USP10/PINK1/TRIM21/IFI16/TECPR1/FBXW7/ERN1/LARP1/VPS37A/ATP6V0A2/HSP90AA1/FLCN/ZC3H12A/RAB3GAP2/CHMP6/SIRT1/SESN2/DDIT3/FNBP1L/SMCR8/HSPB1/UCHL1/ULK2/DAPK2/EEF1A1/FYCO1/VCP/ATG4B/WAC/MTMR14/VPS37B/BMF/SESN3/TMEM150C/FUNDC1/PLK3/FOXK2/MCL1/MTM1/NUPR1/LRSAM1/PRKAG2/RAB12/TREM2/SPATA18/ACBD5/FZD5/CDK5R1/UVRAG/DCN/USP33/VPS26B/IL10RA/MTOR/C19orf12/KDR/DYNLL2/GPSM1/RAB8A/TMEM74/HSPB8/SCOC	79
BP	GO:0019359	nicotinamide nucleotide biosynthetic process	27/2486	147/18670	0.0502	0.1959	0.1536	SLC4A1/NUP93/PFKFB2/DHTKD1/PARP9/ZBTB7A/NUP50/NNMT/QPRT/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/RAE1/NUP188/NUP160/NUP54/NADSYN1/NUP214/NUP155/FOXK2/NUPR1/SLC2A6/PRKAG2/NMNAT3/PFKP	27
BP	GO:0019363	pyridine nucleotide biosynthetic process	27/2486	147/18670	0.0502	0.1959	0.1536	SLC4A1/NUP93/PFKFB2/DHTKD1/PARP9/ZBTB7A/NUP50/NNMT/QPRT/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/RAE1/NUP188/NUP160/NUP54/NADSYN1/NUP214/NUP155/FOXK2/NUPR1/SLC2A6/PRKAG2/NMNAT3/PFKP	27
BP	GO:0051282	regulation of sequestering of calcium ion	24/2486	128/18670	0.05074	0.1961	0.1537	SRI/PDPK1/ITPR1/SNCA/MCOLN3/NOL3/TGFB1/DIAPH1/CX3CL1/DDIT3/P2RX7/PLCB2/PLCB1/APLNR/IBTK/FKBP1B/CCL21/THY1/ANK2/RYR2/LYN/DMD/PTPRC/CORO1A	24
BP	GO:0016525	negative regulation of angiogenesis	31/2486	173/18670	0.05084	0.1961	0.1537	SPRY2/PPARG/SPARC/GTF2I/GHRL/TGFB2/MIR21/FOXC1/GPR4/MMRN2/THBS4/ECSCR/PML/ADAMTS9/CARD10/VASH1/PTN/COL4A2/SULF1/MEOX2/KLF4/CREB3L1/TIE1/NOTCH1/TEK/ANGPT2/PDCD10/MIR214/DCN/SEMA3E/FOXJ2	31
BP	GO:0001779	natural killer cell differentiation	6/2486	21/18670	0.05102	0.1961	0.1537	PGLYRP1/GAS6/SP3/PIK3CD/PTPRC/AXL	6
BP	GO:0031290	retinal ganglion cell axon guidance	6/2486	21/18670	0.05102	0.1961	0.1537	NRCAM/PTPRO/NRP1/SLIT2/SLIT1/EPHB2	6
BP	GO:0033962	cytoplasmic mRNA processing body assembly	6/2486	21/18670	0.05102	0.1961	0.1537	LSM4/ATXN2L/CNOT7/RC3H1/DDX6/CNOT1	6
BP	GO:0035162	embryonic hemopoiesis	6/2486	21/18670	0.05102	0.1961	0.1537	SH2B3/GATA1/PBX1/TAL1/STK4/KDR	6
BP	GO:0035455	response to interferon-alpha	6/2486	21/18670	0.05102	0.1961	0.1537	IFITM3/KLHL20/GAS6/IFIT3/IFITM2/AXL	6
BP	GO:0036344	platelet morphogenesis	6/2486	21/18670	0.05102	0.1961	0.1537	EP300/GATA1/TAL1/ACTN1/MYH9/C1GALT1C1	6
BP	GO:0036499	PERK-mediated unfolded protein response	6/2486	21/18670	0.05102	0.1961	0.1537	PPP1R15A/PPP1R15B/HERPUD1/EIF2S1/DDIT3/HSPA5	6
BP	GO:0043153	entrainment of circadian clock by photoperiod	6/2486	21/18670	0.05102	0.1961	0.1537	RBM4/BHLHE40/PML/MTA1/NR2F6/PER1	6
BP	GO:0046827	positive regulation of protein export from nucleus	6/2486	21/18670	0.05102	0.1961	0.1537	RBM22/GAS6/RAPGEF3/PPM1A/IL1B/ANP32B	6
BP	GO:0048026	positive regulation of mRNA splicing, via spliceosome	6/2486	21/18670	0.05102	0.1961	0.1537	TRA2B/SF3B4/RBM3/RBMXL1/TRA2A/RBMX	6
BP	GO:0055093	response to hyperoxia	6/2486	21/18670	0.05102	0.1961	0.1537	POLB/PPARG/KCNA5/PDGFRB/POLG/CAV1	6
BP	GO:1902884	positive regulation of response to oxidative stress	6/2486	21/18670	0.05102	0.1961	0.1537	TNF/SFPQ/FBXW7/MMP3/MCL1/REST	6
BP	GO:2000738	positive regulation of stem cell differentiation	6/2486	21/18670	0.05102	0.1961	0.1537	TBX5/TGFB2/FOXC1/PTN/SOX9/SOX6	6
BP	GO:2000810	regulation of bicellular tight junction assembly	6/2486	21/18670	0.05102	0.1961	0.1537	CLDN5/TNF/NPHP1/MYO1C/FZD5/TJP1	6
BP	GO:2001014	regulation of skeletal muscle cell differentiation	6/2486	21/18670	0.05102	0.1961	0.1537	AKIRIN1/CYP26B1/SIX1/NR1D2/GPC1/TBX1	6
BP	GO:0043583	ear development	38/2486	219/18670	0.05136	0.1961	0.1537	C1QB/SPRY2/MAF/SLC9A3R1/SPARC/NIPBL/TWIST1/MCOLN3/FOXI1/TGFB2/TGFB1/PVALB/HES1/JAG2/BMP2/WDR19/SOBP/SIX1/SLC25A27/GJB6/SEC24B/PRRX1/KCNK3/PDGFRB/SOX9/NOTCH1/ALDH1A3/GLI3/CTHRC1/WNT5A/MSX1/ROR1/LRIG3/TBX1/SIX2/ANP32B/EPHB2/MYO15A	38
BP	GO:0001732	formation of cytoplasmic translation initiation complex	5/2486	16/18670	0.0514	0.1961	0.1537	EIF5/EIF3L/EIF3F/EIF3K/EIF3M	5
BP	GO:0002295	T-helper cell lineage commitment	5/2486	16/18670	0.0514	0.1961	0.1537	IRF4/IL23R/BATF/MTOR/SPN	5
BP	GO:0010934	macrophage cytokine production	5/2486	16/18670	0.0514	0.1961	0.1537	TGFB2/TGFB1/GAS6/SIRT1/WNT5A	5
BP	GO:0016114	terpenoid biosynthetic process	5/2486	16/18670	0.0514	0.1961	0.1537	DHRS9/ALDH1A3/ALDH1A2/HMGCS1/RBP1	5
BP	GO:0030252	growth hormone secretion	5/2486	16/18670	0.0514	0.1961	0.1537	CDK16/GHRL/SERP1/ADCYAP1/LTBP4	5
BP	GO:0031958	corticosteroid receptor signaling pathway	5/2486	16/18670	0.0514	0.1961	0.1537	RBM14/ARID1A/NR3C1/PER1/NCOA6	5
BP	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation	5/2486	16/18670	0.0514	0.1961	0.1537	ARF1/AP1AR/WASF1/FCHSD2/NCKAP1	5
BP	GO:0044827	modulation by host of viral genome replication	5/2486	16/18670	0.0514	0.1961	0.1537	IFI27/STOM/EIF2AK4/ZC3H12A/CCL8	5
BP	GO:0044849	estrous cycle	5/2486	16/18670	0.0514	0.1961	0.1537	PTN/HAS2/OXTR/HAS1/NCOA1	5
BP	GO:0045623	negative regulation of T-helper cell differentiation	5/2486	16/18670	0.0514	0.1961	0.1537	SMAD7/ZC3H12A/HLX/IL2/RC3H1	5
BP	GO:0048012	hepatocyte growth factor receptor signaling pathway	5/2486	16/18670	0.0514	0.1961	0.1537	SIRT2/NRP1/BCAR1/MST1/ADAMTS12	5
BP	GO:0050711	negative regulation of interleukin-1 secretion	5/2486	16/18670	0.0514	0.1961	0.1537	TNFAIP3/GAS6/ZC3H12A/PML/NLRP7	5
BP	GO:0060965	negative regulation of gene silencing by miRNA	5/2486	16/18670	0.0514	0.1961	0.1537	PPARG/TGFB1/ZC3H12A/NEAT1/ZC3H10	5
BP	GO:0061684	chaperone-mediated autophagy	5/2486	16/18670	0.0514	0.1961	0.1537	CLU/SNCA/HSP90AA1/EEF1A1/PLK3	5
BP	GO:0071380	cellular response to prostaglandin E stimulus	5/2486	16/18670	0.0514	0.1961	0.1537	PPARG/PTGER4/ADCY6/SFRP1/AKAP8	5
BP	GO:0072109	glomerular mesangium development	5/2486	16/18670	0.0514	0.1961	0.1537	GPR4/PDGFRB/CD34/NOTCH1/ACTA2	5
BP	GO:0072189	ureter development	5/2486	16/18670	0.0514	0.1961	0.1537	SIX1/SOX9/ALDH1A2/EMX2/LZTS2	5
BP	GO:1902992	negative regulation of amyloid precursor protein catabolic process	5/2486	16/18670	0.0514	0.1961	0.1537	CLU/SORL1/IGF1/SPON1/PIN1	5
BP	GO:1905153	regulation of membrane invagination	5/2486	16/18670	0.0514	0.1961	0.1537	PPARG/TREM2/CD300A/ITGA2/SYT11	5
BP	GO:0070302	regulation of stress-activated protein kinase signaling cascade	41/2486	239/18670	0.0518	0.1973	0.1547	MMP8/TNF/DLG1/DUSP10/DNAJA1/TGFB2/PINK1/TRAF4/ITCH/PPEF2/FCGR2B/ERN1/ZC3H12A/IGF1R/BMP2/TRAF6/MAP3K2/EGFR/CYLD/SFRP2/SAMD5/MAP3K5/TPD52L1/PLCB1/TNFRSF11A/FZD10/MID1/IL1B/CCL21/SFRP1/FZD5/PDCD10/WNT5A/TLR9/IL26/DUSP1/MAP3K3/LYN/FZD4/PER1/RASSF2	41
BP	GO:2000116	regulation of cysteine-type endopeptidase activity	41/2486	239/18670	0.0518	0.1973	0.1547	PMAIP1/CRADD/FADD/PPARG/TBC1D10A/CASP4/RPS27L/SNCA/TNF/BCL10/LTF/NOL3/IFI16/HERPUD1/GAS6/RAF1/SIRT1/ASPH/SFRP2/PML/MAP3K5/VCP/PRR7/MMP9/WNT9A/AQP1/KLF4/SERPINB9/IFI6/DIABLO/NLRP1/REST/PPM1F/DLC1/TRIAP1/BAK1/PDCD5/ANP32B/MGMT/CRYAB/CIDEB	41
BP	GO:1903409	reactive oxygen species biosynthetic process	23/2486	122/18670	0.0521	0.1984	0.1555	CLU/HBB/DDAH1/MMP8/ARG2/SLC25A33/SNCA/TNF/HSP90AA1/MIR21/ZC3H12A/GCH1/NOS3/ASS1/KLF4/CD34/ACP5/IL1B/NOX4/HSP90AB1/CAV1/MTOR/NQO1	23
BP	GO:0006090	pyruvate metabolic process	28/2486	154/18670	0.05227	0.1986	0.1556	PDPR/ME1/SLC4A1/NUP93/PFKFB2/LDHC/DHTKD1/ZBTB7A/NUP50/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/RAE1/NUP188/NUP160/NUP54/PDP1/NUP214/NUP155/FOXK2/NUPR1/SLC2A6/PRKAG2/ME3/PDK4/PFKP	28
BP	GO:0010863	positive regulation of phospholipase C activity	10/2486	43/18670	0.05246	0.1986	0.1556	NTF3/ARHGAP6/BDNF/FLT1/P2RY12/EGFR/NTRK2/PLCB2/PDGFRA/PDGFRB	10
BP	GO:0021795	cerebral cortex cell migration	10/2486	43/18670	0.05246	0.1986	0.1556	FGF13/LHX6/NRP1/P2RY12/EGFR/GLI3/LAMB1/CDK5R1/SLIT2/SUN2	10
BP	GO:0030866	cortical actin cytoskeleton organization	10/2486	43/18670	0.05246	0.1986	0.1556	CIT/RTKN/RAB13/TNF/DLG1/ANLN/FMNL1/EHD2/NCKAP1/EPB41L1	10
BP	GO:0033173	calcineurin-NFAT signaling cascade	10/2486	43/18670	0.05246	0.1986	0.1556	FHL2/TNF/SPPL3/LMCD1/RCAN2/NFATC4/IGF1/PPP3CB/MTOR/NFATC3	10
BP	GO:0038202	TORC1 signaling	10/2486	43/18670	0.05246	0.1986	0.1556	RRAGA/DEPDC5/LARP1/FLCN/TELO2/SESN2/SMCR8/SESN3/SIK3/MTOR	10
BP	GO:0042088	T-helper 1 type immune response	10/2486	43/18670	0.05246	0.1986	0.1556	IL1R1/HLX/TRAF6/IL23R/IL12A/TMEM98/IL1B/IL33/MTOR/SPN	10
BP	GO:0045746	negative regulation of Notch signaling pathway	10/2486	43/18670	0.05246	0.1986	0.1556	PEAR1/NFKBIA/YTHDF2/FBXW7/JAG2/ZBTB7A/EGFL7/EGFR/EGF/NOTCH3	10
BP	GO:0043255	regulation of carbohydrate biosynthetic process	19/2486	97/18670	0.05253	0.1986	0.1556	GNMT/EP300/SNCA/CD244/TGFB1/WDR5/SMPD3/SIRT1/SESN2/IGF1/EGF/PTH1R/IRS2/HRH1/FOXK2/HAS2/SORBS1/MTOR/MST1	19
BP	GO:1990868	response to chemokine	19/2486	97/18670	0.05253	0.1986	0.1556	CXCL5/SH2B3/CX3CL1/ZC3H12A/FOXC1/CXCR1/CCL13/LOX/GPR35/CXCL12/CXCL6/CCL21/TREM2/CXCL1/CCL8/DUSP1/SLIT2/CCL18/DOCK8	19
BP	GO:1990869	cellular response to chemokine	19/2486	97/18670	0.05253	0.1986	0.1556	CXCL5/SH2B3/CX3CL1/ZC3H12A/FOXC1/CXCR1/CCL13/LOX/GPR35/CXCL12/CXCL6/CCL21/TREM2/CXCL1/CCL8/DUSP1/SLIT2/CCL18/DOCK8	19
BP	GO:0051495	positive regulation of cytoskeleton organization	39/2486	226/18670	0.05253	0.1986	0.1556	RHOBTB1/CTTN/NTF3/BAG4/NAV3/ARF1/PLXNA3/DLG1/TPM1/NRP1/CX3CL1/RAPGEF3/P2RX7/AP1AR/NIN/LMOD1/WHAMM/WASF1/MYO1C/TEK/FCHSD2/CCL21/SFRP1/NES/CDK5R1/NCKAP1/NOX4/PPM1F/FLNA/ARPC2/HCLS1/MTOR/CLASP1/PFN1/CDC42EP5/CORO1A/ARHGEF15/LIMCH1/MAGEL2	39
BP	GO:0060828	regulation of canonical Wnt signaling pathway	48/2486	286/18670	0.05258	0.1986	0.1557	PSMD14/PSMD12/SLC9A3R1/FAM53B/PTPRO/APC/PLEKHA4/WNT5B/PSMD7/PSMB5/IGFBP2/DAAM2/PRDM15/BMP2/DAB2/DDIT3/WWTR1/JUP/EGFR/CYLD/SFRP2/EGF/VCP/CSNK1A1/IGFBP4/STK4/ZBED2/CCNY/SFRP4/PPM1A/RSPO3/PSMB7/SOX9/NOTCH1/YAP1/GLI3/CTHRC1/PSMD1/SFRP1/PSMD9/WNT5A/CAV1/RBMS3/PSME1/RNF220/DKK3/LZTS2/PIN1	48
BP	GO:0030010	establishment of cell polarity	25/2486	135/18670	0.05323	0.2009	0.1575	SPRY2/FGF13/SLC9A3R1/MPP5/PARD3/CRKL/FRMD4A/SPRY1/HES1/CYP26B1/HSP90AA1/MSN/MAP2/AMOTL2/PLK1/MYH9/CCL21/MPP7/WNT5A/NDE1/CDH5/ALPK2/HSP90AB1/CLASP1/DOCK8	25
BP	GO:0006757	ATP generation from ADP	22/2486	116/18670	0.05346	0.2016	0.158	SLC4A1/NUP93/PFKFB2/DHTKD1/ZBTB7A/NUP50/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/RAE1/NUP188/NUP160/NUP54/NUP214/NUP155/FOXK2/NUPR1/SLC2A6/PRKAG2/PFKP	22
BP	GO:0045638	negative regulation of myeloid cell differentiation	18/2486	91/18670	0.05347	0.2016	0.158	KLF13/C1QC/INPP5D/INHBA/NFKBIA/HOXA7/LTF/TAL1/LDB1/ZFP36/FBXW7/MEIS2/CEACAM1/SFRP1/LYN/HOXA9/FBN1/HSPA9	18
BP	GO:0002448	mast cell mediated immunity	11/2486	49/18670	0.0542	0.2039	0.1598	PDPK1/STXBP1/BTK/C12orf4/CBL/PIK3CD/IL13RA2/SERPINB9/SNAP23/CD300A/LYN	11
BP	GO:0032757	positive regulation of interleukin-8 production	11/2486	49/18670	0.0542	0.2039	0.1598	FADD/TNF/BCL10/CD244/ELANE/DDIT3/AFAP1L2/IL1B/IL17D/WNT5A/TLR9	11
BP	GO:0003176	aortic valve development	8/2486	32/18670	0.05422	0.2039	0.1598	HEYL/TWIST1/TGFB1/ELN/NOS3/SOX9/NOTCH1/SLIT2	8
BP	GO:0042744	hydrogen peroxide catabolic process	8/2486	32/18670	0.05422	0.2039	0.1598	HBB/HBD/SNCA/PRDX2/PXDN/HBM/HP/HBQ1	8
BP	GO:0032635	interleukin-6 production	29/2486	161/18670	0.05423	0.2039	0.1598	ORM1/INPP5D/MMP8/TNFAIP3/MBP/TNF/TWIST1/BCL10/LPL/GHRL/DHX9/GAS6/CX3CL1/ZC3H12A/TRAF6/IFIH1/P2RX7/RAB7B/AFAP1L2/IL1B/IL17D/IL33/TREM2/WNT5A/TLR9/TBC1D23/ADCYAP1/NR1H4/SYT11	29
BP	GO:0006939	smooth muscle contraction	21/2486	110/18670	0.05479	0.2058	0.1613	CTTN/EDNRB/DLG1/GHRL/TACR1/ADRA2A/MIR21/GRIP2/BDKRB2/EDN3/CALCRL/NPNT/SULF1/KCNMA1/SMTN/FKBP1B/OXTR/CAV1/ITGA2/ACTA2/ABAT	21
BP	GO:0002064	epithelial cell development	36/2486	207/18670	0.05506	0.2067	0.162	SLC9A3R1/PDPK1/CLDN5/TMOD1/MYADM/YIPF6/PROC/RAB13/TNF/WNT5B/PDE2A/ARID4A/RAPGEF3/GPR4/COL18A1/STC1/MSN/SEC24B/SMO/FAT1/BFSP1/FRS2/SOX9/KLF5/NOTCH1/IL1B/DACT2/NUP210L/WNT5A/FLNA/TJP1/MAGI2/PODXL/CDH5/ACTA2/SPINT2	36
BP	GO:0003229	ventricular cardiac muscle tissue development	12/2486	55/18670	0.05522	0.2067	0.162	TBX5/SMAD7/TGFB2/TGFB1/TPM1/FOXC1/ADAMTS9/UBE4B/POU4F1/NOTCH1/ZFPM2/RYR2	12
BP	GO:0032781	positive regulation of ATPase activity	12/2486	55/18670	0.05522	0.2067	0.162	GABARAPL2/MYL4/DNAJA1/ATP1B2/DHX9/TPM1/DNAJC10/DNAJC24/RYR2/DNAJA2/DYNLL2/PFN1	12
BP	GO:0042304	regulation of fatty acid biosynthetic process	12/2486	55/18670	0.05522	0.2067	0.162	FABP5/ERLIN1/APOC1/SIRT1/ERLIN2/ADIPOR2/CEACAM1/PRKAG2/IL1B/WDTC1/PDK4/ELOVL5	12
BP	GO:0043551	regulation of phosphatidylinositol 3-kinase activity	12/2486	55/18670	0.05522	0.2067	0.162	SOCS7/FLT1/TGFB1/P2RY12/PDGFRA/KLF4/PDGFRB/TEK/CCL21/WDR91/VAV3/LYN	12
BP	GO:0045620	negative regulation of lymphocyte differentiation	12/2486	55/18670	0.05522	0.2067	0.162	INHBA/PGLYRP1/IRF1/SMAD7/PRDX2/MIR21/ZC3H12A/HLX/IL2/GLI3/SFRP1/RC3H1	12
BP	GO:0003208	cardiac ventricle morphogenesis	15/2486	73/18670	0.0555	0.2076	0.1627	HEYL/TBX5/SMAD7/TGFB2/TGFB1/TPM1/FOXC1/SFRP2/CPE/UBE4B/MIR17HG/POU4F1/NOTCH1/ZFPM2/RYR2	15
BP	GO:0050803	regulation of synapse structure or activity	39/2486	227/18670	0.05558	0.2078	0.1629	NRCAM/PTPRO/SPARC/BDNF/SNCA/TNF/GHRL/CRKL/CUX2/SSH1/AGRN/CTTNBP2/FCGR2B/GPC4/TPBG/NFATC4/NTRK2/LRRN1/SEMA4D/YWHAZ/PTN/VCP/SIX1/FLRT2/CRIPT/SRPX2/DNM1/GAP43/CDK5R1/OXTR/WNT5A/PAK3/IGSF9/IL10RA/ARC/SLIT1/EPHB2/ARHGEF15/SHANK3	39
BP	GO:0007405	neuroblast proliferation	13/2486	61/18670	0.0557	0.208	0.163	FGF13/DAGLB/VEGFC/TGFB1/CX3CL1/PTN/SMO/FRS2/NOTCH1/KCNA1/GLI3/NDE1/EML1	13
BP	GO:0032233	positive regulation of actin filament bundle assembly	13/2486	61/18670	0.0557	0.208	0.163	BAG4/TPM1/NRP1/CX3CL1/RAPGEF3/SFRP1/NOX4/PPM1F/FLNA/MTOR/PFN1/ARHGEF15/LIMCH1	13
BP	GO:0042108	positive regulation of cytokine biosynthetic process	14/2486	67/18670	0.05576	0.2081	0.1631	IRF1/TNF/BCL10/ELANE/CD276/IRF4/TRAF6/HSPB1/RELA/IL1B/WNT5A/TLR9/SPN/PTPRC	14
BP	GO:0001906	cell killing	30/2486	168/18670	0.05609	0.2091	0.1639	FAM49B/CD1C/CR1L/CFH/CTSG/FADD/ARG1/LYST/PGLYRP1/LTF/CD59/ELANE/FCGR2B/CD1B/CAMP/CCL13/IL23R/VAV1/P2RX7/CXCL6/HLA-B/CEACAM1/IL12A/SERPINB9/EMP2/PPP3CB/HSP90AB1/PTPRC/CORO1A/HLA-A	30
BP	GO:0030593	neutrophil chemotaxis	20/2486	104/18670	0.05609	0.2091	0.1639	CXCL5/TGFB2/CX3CL1/CXCR1/PDE4B/EDN3/THBS4/CCL13/VAV1/ITGA9/DAPK2/CXCL6/PIK3CD/IL1B/CCL21/CXCL1/VAV3/CCL8/SLIT2/CCL18	20
BP	GO:0060249	anatomical structure homeostasis	70/2486	437/18670	0.05617	0.2092	0.164	ITGB3/INPP5D/TNFAIP3/XRCC6/PRIM2/PARP3/RFC1/POLE3/GATA1/CSF1/LIPA/SMC5/TUB/TMEM119/LTF/TGFB1/LDB1/CX3CL1/HSP90AA1/DCP2/ABCA4/FOXC1/EXO1/CLN8/TELO2/FBXO4/USP7/POLE/DCLRE1A/SPP1/TRAF6/WWTR1/MDM1/EGFR/LOX/NOS3/HSPB1/P2RX7/PML/PIGR/PKIB/PTH1R/BBS1/TNFRSF11A/SMO/CCT8/MTM1/SOX9/RECQL4/CD34/NOTCH1/ACP5/SERPINA3/YAP1/CIB2/MUC2/NOX4/SMG6/TLR9/HSP90AB1/MAPKAPK5/TNKS1BP1/DMD/PDK4/BARD1/CORO1A/NHP2/NEK2/LPCAT1/ZNF830	70
BP	GO:0007254	JNK cascade	37/2486	214/18670	0.05635	0.2098	0.1644	MMP8/TNF/DUSP10/DNAJA1/CRKL/PINK1/TRAF4/UBA52/ITCH/PPEF2/FCGR2B/ERN1/IGF1R/PTGER4/TRAF6/MAP3K2/EGFR/CYLD/SFRP2/SAMD5/MAP3K5/TPD52L1/PLCB1/TNFRSF11A/FZD10/IL1B/CCL21/SFRP1/FZD5/UBC/WNT5A/TLR9/SH2D3C/FZD4/CDC42EP5/PER1/RASSF2	37
BP	GO:0060191	regulation of lipase activity	19/2486	98/18670	0.05735	0.2134	0.1673	NTF3/ARHGAP6/PDPK1/BDNF/SNCA/FLT1/LPL/PLA2G5/PCSK6/P2RY12/APOC1/ANGPTL4/EGFR/NTRK2/PLCB2/GPIHBP1/PDGFRA/AGTR1/PDGFRB	19
BP	GO:0043902	positive regulation of multi-organism process	33/2486	188/18670	0.05752	0.2139	0.1676	SIRT2/STOM/EDNRB/ARG1/INHBA/EP300/PGLYRP1/CAV2/JUN/DHX9/CDK9/TRIM21/ADARB1/SRPK2/PPID/LARP1/CHD1/TRAF6/POLR2G/PLCB1/VPS37B/RSF1/IFIT1/NOTCH1/LRSAM1/OXTR/PKN2/CNOT7/UNC13B/POLR2D/STAU1/NR5A2/ZCCHC3	33
BP	GO:2000181	negative regulation of blood vessel morphogenesis	31/2486	175/18670	0.05786	0.215	0.1685	SPRY2/PPARG/SPARC/GTF2I/GHRL/TGFB2/MIR21/FOXC1/GPR4/MMRN2/THBS4/ECSCR/PML/ADAMTS9/CARD10/VASH1/PTN/COL4A2/SULF1/MEOX2/KLF4/CREB3L1/TIE1/NOTCH1/TEK/ANGPT2/PDCD10/MIR214/DCN/SEMA3E/FOXJ2	31
BP	GO:0009649	entrainment of circadian clock	7/2486	27/18670	0.05861	0.2172	0.1702	RBM4/ARNTL2/BHLHE40/PML/MTA1/NR2F6/PER1	7
BP	GO:0048668	collateral sprouting	7/2486	27/18670	0.05861	0.2172	0.1702	FGF13/BDNF/RND2/SPP1/SEMA4D/ULK2/NIN	7
BP	GO:0060384	innervation	7/2486	27/18670	0.05861	0.2172	0.1702	ITGA4/NRP1/ADARB1/SULF1/LRIG2/POU4F1/UNC13B	7
BP	GO:0071450	cellular response to oxygen radical	7/2486	27/18670	0.05861	0.2172	0.1702	TNF/PRDX2/MIR21/GCH1/NOS3/SOD3/NQO1	7
BP	GO:0071451	cellular response to superoxide	7/2486	27/18670	0.05861	0.2172	0.1702	TNF/PRDX2/MIR21/GCH1/NOS3/SOD3/NQO1	7
BP	GO:1901991	negative regulation of mitotic cell cycle phase transition	42/2486	248/18670	0.05878	0.2177	0.1706	MUC1/PSMD14/PSMD12/CRADD/CNOT8/CNOT4/EP300/RPS27L/SYF2/APC/PSMD7/PSMB5/KANK2/CCND1/CTDSPL/CDKN2C/MIR21/MDM4/PML/FOXN3/BUB1B/CDK2AP2/PLK3/PSMB7/KLF4/PLK1/PSMD1/BTG2/CDKN2B/PSMD9/GPNMB/FAM107A/DUSP1/CNOT7/TTK/TRIAP1/TNKS1BP1/E2F8/PSME1/CNOT1/CUL1/ZNF830	42
BP	GO:0052547	regulation of peptidase activity	72/2486	452/18670	0.05897	0.2183	0.1711	PROS1/SLPI/PSMD14/PMAIP1/CRADD/MBP/FADD/PPARG/TBC1D10A/CASP4/RPS27L/SNCA/TNF/CD109/BCL10/LTF/NOL3/PCOLCE2/PINK1/SORL1/IFI16/HERPUD1/GAS6/MIR21/UBXN1/RAF1/FN1/SIRT1/SERPING1/ASPH/ECM1/SFRP2/SERPINH1/PML/WFDC1/MAP3K5/PCOLCE/VCP/TFPI/PRR7/MMP9/WNT9A/TIMP3/AQP1/KLF4/SERPINB9/WFDC3/IFI6/SERPINA3/DIABLO/TIMP4/NLRP1/REST/PPM1F/FBLN1/CAV1/LYN/ITIH2/DLC1/TRIAP1/BAK1/PDCD5/PSME1/A2M/ANP32B/SPINT2/MGMT/CRYAB/LXN/RARRES1/NLRP7/CIDEB	72
BP	GO:0019884	antigen processing and presentation of exogenous antigen	32/2486	182/18670	0.05953	0.2202	0.1726	CD1C/PSMD14/PSMD12/ITGB5/HLA-DPB1/KIF26A/ARF1/DYNC1I1/PSMD7/PDIA3/PSMB5/ACTR10/FCGR2B/CD1B/TRAF6/KIF4A/AP2A2/HLA-B/SEC24B/PSMB7/KIF2C/CAPZA1/SNAP23/PSMD1/PSMD9/CTSF/DYNLL2/PSME1/AP1S3/DCTN4/HLA-A/KLC1	32
BP	GO:0032760	positive regulation of tumor necrosis factor production	17/2486	86/18670	0.05963	0.2204	0.1728	CLU/ORM1/MMP8/FADD/ARFGEF2/TWIST1/LPL/DHX9/NFATC4/IFIH1/HSPB1/FZD5/WNT5A/TLR9/SPN/FRMD8/PTPRC	17
BP	GO:0034767	positive regulation of ion transmembrane transport	28/2486	156/18670	0.05991	0.2213	0.1735	SRI/SLC9A3R1/PDPK1/ARF1/SNCA/ATP1B2/PINK1/FGF14/CACNB3/CX3CL1/MIR21/EDN3/STAC/P2RX7/STAC2/RAMP3/FXYD1/APLNR/KCNA1/THY1/TREM2/ANK2/FLNA/RYR2/DMD/ARC/EPHB2/SHANK3	28
BP	GO:0030225	macrophage differentiation	10/2486	44/18670	0.06011	0.2217	0.1738	C1QC/FADD/INHBA/CSF1/L3MBTL3/TGFB1/CEBPE/SIRT1/MMP9/HCLS1	10
BP	GO:0045601	regulation of endothelial cell differentiation	10/2486	44/18670	0.06011	0.2217	0.1738	CLDN5/PROC/TNF/MIR21/CEACAM1/NOTCH1/IL1B/APOLD1/CDH5/FOXJ2	10
BP	GO:2000404	regulation of T cell migration	10/2486	44/18670	0.06011	0.2217	0.1738	FADD/ITGA4/CRKL/ECM1/CXCL12/TNFRSF14/CCL21/WNT5A/SPN/DOCK8	10
BP	GO:0009746	response to hexose	35/2486	202/18670	0.06045	0.2227	0.1745	SRI/LRP5L/TRA2B/SLC2A5/CDK16/LPL/GHRL/TGFB1/TRH/PFKFB2/RAB11FIP5/C2CD2L/GAS6/ERN1/ADRA2A/RAF1/IGF1R/SESN2/JAGN1/GJB6/IRS2/SLC26A6/KHK/POLG/STX4/FKBP1B/ANGPT2/PPP3CB/NOX4/COL6A2/UNC13B/NR1H4/LRP5/SIN3A/EIF2B2	35
BP	GO:0050852	T cell receptor signaling pathway	35/2486	202/18670	0.06045	0.2227	0.1745	PSMD14/PSMD12/PDPK1/INPP5D/HLA-DPB1/BCL10/SPPL3/CRKL/PSMD7/PSMB5/BTNL8/CD276/CACNB3/ZC3H12A/NFKBIZ/PDE4B/BTK/TRAF6/CYLD/RELA/CEACAM1/PIK3CD/PSMB7/BCAR1/PSMD1/THY1/PSMD9/BTNL9/PAK3/CD300A/PSME1/RC3H1/PTPRC/EIF2B2/CUL1	35
BP	GO:0046717	acid secretion	23/2486	124/18670	0.06078	0.2238	0.1754	SLC9A3R1/SNCA/GHRL/SCT/SLC1A3/CYP4F2/TRH/PLA2G5/ACE/STXBP1/BDKRB2/NTRK2/P2RX7/SLC1A1/TNFRSF11A/SLC26A6/IL1B/PLA2G2A/OXTR/UNC13B/GIPC1/SLC6A1/ABAT	23
BP	GO:0008593	regulation of Notch signaling pathway	20/2486	105/18670	0.06097	0.2243	0.1758	PEAR1/EP300/NFKBIA/YTHDF2/TGFB2/HES1/FBXW7/JAG2/CREBBP/ZBTB7A/EGFL7/EGFR/NOS3/EGF/MFNG/TSPAN14/NOTCH1/PDCD10/POSTN/NOTCH3	20
BP	GO:0014015	positive regulation of gliogenesis	15/2486	74/18670	0.06139	0.2253	0.1766	PPARG/CSF1/TNF/CRKL/TGFB1/HES1/P2RY12/BMP2/RELA/PTN/NOTCH1/IL1B/TREM2/MTOR/LYN	15
BP	GO:0032507	maintenance of protein location in cell	15/2486	74/18670	0.06139	0.2253	0.1766	VPS13C/PINK1/SORL1/JUP/PML/TAF3/PFN4/TMSB4Y/KDELR3/TMSB15A/RANGAP1/CAV1/HSPA5/BARD1/SUN2	15
BP	GO:0032677	regulation of interleukin-8 production	15/2486	74/18670	0.06139	0.2253	0.1766	FADD/TNF/BCL10/CD244/ELANE/DDIT3/KLF4/AFAP1L2/OTUD7B/IL1B/IL17D/SSC5D/WNT5A/TLR9/PTPRC	15
BP	GO:0009409	response to cold	11/2486	50/18670	0.06146	0.2253	0.1766	GMPR/PPARG/NFKBIA/EIF2AK4/LPL/TRH/RBM3/HSP90AA1/FOS/SLC25A27/LRP11	11
BP	GO:0060976	coronary vasculature development	11/2486	50/18670	0.06146	0.2253	0.1766	LTBP1/TBX5/NRP1/SGCD/SEC24B/APLNR/PDGFRB/NOTCH1/TBX1/MYH10/SETD2	11
BP	GO:0086009	membrane repolarization	11/2486	50/18670	0.06146	0.2253	0.1766	SCN1B/DLG1/ATP1B2/CACNB3/GJA5/KCND3/KCNA5/KCNJ8/ANK2/FLNA/CAV1	11
BP	GO:0099173	postsynapse organization	29/2486	163/18670	0.0619	0.2263	0.1774	NRCAM/CTTN/ARF1/WASF2/DLG1/GHRL/CRKL/CUX2/SSH1/NRP1/FCGR2B/NEFH/DLG2/IGF1R/ITGA3/PTN/CRIPT/ACTN1/GAP43/CDK5R1/WNT5A/PAK3/MAGI2/NLGN4X/MYH10/ARC/GLRB/EPHB2/SHANK3	29
BP	GO:0072525	pyridine-containing compound biosynthetic process	27/2486	150/18670	0.06191	0.2263	0.1774	SLC4A1/NUP93/PFKFB2/DHTKD1/PARP9/ZBTB7A/NUP50/NNMT/QPRT/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/RAE1/NUP188/NUP160/NUP54/NADSYN1/NUP214/NUP155/FOXK2/NUPR1/SLC2A6/PRKAG2/NMNAT3/PFKP	27
BP	GO:0050769	positive regulation of neurogenesis	75/2486	474/18670	0.06196	0.2263	0.1774	NRCAM/SCN1B/SPEN/GRIP1/MME/ZNF609/PPARG/EP300/ARF1/HEYL/BDNF/TRAK1/PLXNA3/CSF1/NIPBL/TNF/CRKL/CUX2/VEGFC/TGFB1/RND2/PACSIN1/HES1/NRP1/L1CAM/FBXO38/FBXW8/CX3CL1/P2RY12/FN1/BMP2/IRX3/NTRK2/AVIL/SEMA4D/OBSL1/SKIL/TGIF2/RELA/CXCL12/ITGA3/ITSN2/PTN/NIN/NAP1L1/DPYSL3/IL2/CDON/SMO/NOTCH1/SHOX2/GLI3/PLXNA1/IL1B/FKBP1B/TREM2/REST/WNT5A/PAK3/FLNA/MAGI2/SLIT2/MTOR/LYN/MAN2A1/RGS14/ADCYAP1/FZD4/STYXL1/HSPA5/EPHB2/SIN3A/SHANK3/GDI1/NCOA1	75
BP	GO:0002292	T cell differentiation involved in immune response	14/2486	68/18670	0.06196	0.2263	0.1774	SMAD7/MIR21/ZC3H12A/IRF4/NFKBIZ/HLX/PTGER4/IL23R/BATF/TMEM98/IL2/MTOR/SPN/RC3H1	14
BP	GO:0001912	positive regulation of leukocyte mediated cytotoxicity	12/2486	56/18670	0.06211	0.2263	0.1774	FAM49B/CD1C/FADD/ARG1/CD1B/IL23R/VAV1/P2RX7/HLA-B/IL12A/PTPRC/HLA-A	12
BP	GO:0002381	immunoglobulin production involved in immunoglobulin mediated immune response	12/2486	56/18670	0.06211	0.2263	0.1774	MSH6/PARP3/TGFB1/EXO1/BTK/EXOSC3/BATF/IL2/GAPT/POU2F2/PTPRC/RNF8	12
BP	GO:0065002	intracellular protein transmembrane transport	12/2486	56/18670	0.06211	0.2263	0.1774	SEC62/TIMM23/DNLZ/SEC61B/TOMM20/RTN2/TIMM44/TIMM10/TRAM1L1/GRPEL1/HSPA5/SRP54	12
BP	GO:0086002	cardiac muscle cell action potential involved in contraction	12/2486	56/18670	0.06211	0.2263	0.1774	SCN1B/DLG1/GJA5/JUP/KCND3/KCNA5/NUP155/KCNJ8/ANK2/FLNA/RYR2/CAV1	12
BP	GO:0086065	cell communication involved in cardiac conduction	12/2486	56/18670	0.06211	0.2263	0.1774	SRI/SCN1B/ATP1B2/GJA5/JUP/KCNA5/NUP155/FKBP1B/ANK2/FLNA/RYR2/CAV1	12
BP	GO:0045453	bone resorption	13/2486	62/18670	0.06224	0.2263	0.1774	ITGB3/INPP5D/TNFAIP3/TMEM119/SPP1/TRAF6/EGFR/P2RX7/PTH1R/TNFRSF11A/ACP5/NOX4/PDK4	13
BP	GO:0030838	positive regulation of actin filament polymerization	19/2486	99/18670	0.06247	0.2263	0.1774	RHOBTB1/CTTN/BAG4/ARF1/DLG1/AP1AR/LMOD1/WHAMM/WASF1/MYO1C/FCHSD2/CCL21/NCKAP1/ARPC2/MTOR/PFN1/CDC42EP5/CORO1A/MAGEL2	19
BP	GO:0070301	cellular response to hydrogen peroxide	19/2486	99/18670	0.06247	0.2263	0.1774	MAP1LC3A/TNFAIP3/ARG1/FXN/PINK1/LCN2/KDM6B/MIR21/SMPD3/PYCR1/SIRT1/MAP3K5/RELA/AQP1/KLF4/PDCD10/PCGF2/AXL/NQO1	19
BP	GO:0009190	cyclic nucleotide biosynthetic process	6/2486	22/18670	0.06254	0.2263	0.1774	ADCY3/GUCY2D/ADCY7/ADCY4/ADCY6/AMPD2	6
BP	GO:0031342	negative regulation of cell killing	6/2486	22/18670	0.06254	0.2263	0.1774	FCGR2B/CEACAM1/SERPINB9/PPP3CB/HSP90AB1/PTPRC	6
BP	GO:0045649	regulation of macrophage differentiation	6/2486	22/18670	0.06254	0.2263	0.1774	C1QC/FADD/INHBA/CSF1/TGFB1/HCLS1	6
BP	GO:0045663	positive regulation of myoblast differentiation	6/2486	22/18670	0.06254	0.2263	0.1774	AKIRIN1/BOC/MAP3K5/PLCB1/CDON/IGFBP3	6
BP	GO:0045717	negative regulation of fatty acid biosynthetic process	6/2486	22/18670	0.06254	0.2263	0.1774	ERLIN1/APOC1/SIRT1/ERLIN2/CEACAM1/WDTC1	6
BP	GO:0048305	immunoglobulin secretion	6/2486	22/18670	0.06254	0.2263	0.1774	TNF/TRAF6/IL2/STX4/IL33/POU2F2	6
BP	GO:0052652	cyclic purine nucleotide metabolic process	6/2486	22/18670	0.06254	0.2263	0.1774	ADCY3/GUCY2D/ADCY7/ADCY4/ADCY6/AMPD2	6
BP	GO:0090189	regulation of branching involved in ureteric bud morphogenesis	6/2486	22/18670	0.06254	0.2263	0.1774	TGFB1/SIX1/HOXB7/SMO/SOX9/SIX2	6
BP	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus	6/2486	22/18670	0.06254	0.2263	0.1774	EP300/SMAD1/BMP2/SESN2/RELA/NOTCH1	6
BP	GO:1903077	negative regulation of protein localization to plasma membrane	6/2486	22/18670	0.06254	0.2263	0.1774	TGFB1/DAB2/BCL2L1/LRRC15/PKDCC/MRAP2	6
BP	GO:0010837	regulation of keratinocyte proliferation	8/2486	33/18670	0.06355	0.2283	0.1789	CD109/ZFP36/MIR21/EFNB2/HAS2/NOTCH2/YAP1/INTU	8
BP	GO:0070536	protein K63-linked deubiquitination	8/2486	33/18670	0.06355	0.2283	0.1789	PSMD14/TNFAIP3/OTUD4/SPATA2/CYLD/VCP/OTUD7B/USP33	8
BP	GO:0071985	multivesicular body sorting pathway	8/2486	33/18670	0.06355	0.2283	0.1789	SYTL4/LYST/VPS37A/CHMP1B/VCP/VPS37B/LAPTM4B/UVRAG	8
BP	GO:2000352	negative regulation of endothelial cell apoptotic process	8/2486	33/18670	0.06355	0.2283	0.1789	PDPK1/TNFAIP3/GAS6/ANGPTL4/RAMP2/PAK4/TEK/KDR	8
BP	GO:0046634	regulation of alpha-beta T cell activation	18/2486	93/18670	0.06393	0.2283	0.1789	ARG2/IRF1/SMAD7/CD83/TWSG1/MIR21/ZC3H12A/IRF4/NFKBIZ/HLX/IL23R/IL12A/IL2/TNFRSF14/GLI3/CD300A/RC3H1/PTPRC	18
BP	GO:0003015	heart process	48/2486	290/18670	0.06394	0.2283	0.1789	SRI/SCN1B/ITPR1/CACNA2D2/MYL4/SMAD7/DLG1/TGFB2/ATP1B2/TPM1/AKAP13/CACNB3/ACE/GJA5/ZC3H12A/THRB/PDE4B/SGCD/EDN3/ASPH/WWTR1/JUP/GCH1/KCND3/NOS3/STC1/SLC1A1/KCNA5/CACNA2D3/IL2/RAMP3/FXYD1/NUP155/KCNK3/KCNJ8/TBX2/YAP1/KCNK6/FKBP1B/ANK2/NOX4/FLNA/RYR2/CAV1/MTOR/DMD/KCNK1/ADORA3	48
BP	GO:1904064	positive regulation of cation transmembrane transport	26/2486	144/18670	0.06396	0.2283	0.1789	SRI/PDPK1/ARF1/SNCA/ATP1B2/PINK1/FGF14/CACNB3/CX3CL1/MIR21/EDN3/STAC/STAC2/RAMP3/FXYD1/APLNR/KCNA1/THY1/TREM2/ANK2/FLNA/RYR2/DMD/ARC/EPHB2/SHANK3	26
BP	GO:0031570	DNA integrity checkpoint	28/2486	157/18670	0.06402	0.2283	0.1789	MUC1/CRADD/CNOT8/CNOT4/EP300/RPS27L/SYF2/EIF2AK4/CCND1/MIR21/FBXO4/USP28/MDM4/PML/FOXN3/WAC/CDC45/PLK3/PLK1/BTG2/CNOT7/TRIAP1/TNKS1BP1/E2F8/MUS81/CDC5L/CNOT1/ZNF830	28
BP	GO:0002002	regulation of angiotensin levels in blood	4/2486	12/18670	0.06424	0.2283	0.1789	MME/CTSG/ACE/ENPEP	4
BP	GO:0002003	angiotensin maturation	4/2486	12/18670	0.06424	0.2283	0.1789	MME/CTSG/ACE/ENPEP	4
BP	GO:0002903	negative regulation of B cell apoptotic process	4/2486	12/18670	0.06424	0.2283	0.1789	BCL10/MIR17HG/IRS2/IL2	4
BP	GO:0002921	negative regulation of humoral immune response	4/2486	12/18670	0.06424	0.2283	0.1789	CD59/FCGR2B/SERPING1/A2M	4
BP	GO:0006983	ER overload response	4/2486	12/18670	0.06424	0.2283	0.1789	PPP1R15B/DDIT3/WFS1/HSPA5	4
BP	GO:0009111	vitamin catabolic process	4/2486	12/18670	0.06424	0.2283	0.1789	CYP4F2/CYP26B1/CBR3/CRABP1	4
BP	GO:0009886	post-embryonic animal morphogenesis	4/2486	12/18670	0.06424	0.2283	0.1789	MFAP2/EFEMP1/BAK1/FBN1	4
BP	GO:0010960	magnesium ion homeostasis	4/2486	12/18670	0.06424	0.2283	0.1789	CNNM4/EDN3/EGFR/KCNA1	4
BP	GO:0038180	nerve growth factor signaling pathway	4/2486	12/18670	0.06424	0.2283	0.1789	NTF3/BDNF/MAGI2/CORO1A	4
BP	GO:0042340	keratan sulfate catabolic process	4/2486	12/18670	0.06424	0.2283	0.1789	ACAN/OGN/FMOD/PRELP	4
BP	GO:0042416	dopamine biosynthetic process	4/2486	12/18670	0.06424	0.2283	0.1789	SNCA/TGFB2/GCH1/NR4A2	4
BP	GO:0045161	neuronal ion channel clustering	4/2486	12/18670	0.06424	0.2283	0.1789	NRCAM/GLDN/AGRN/SCLT1	4
BP	GO:0045416	positive regulation of interleukin-8 biosynthetic process	4/2486	12/18670	0.06424	0.2283	0.1789	TNF/BCL10/ELANE/TLR9	4
BP	GO:0048484	enteric nervous system development	4/2486	12/18670	0.06424	0.2283	0.1789	EDNRB/KIF26A/PHACTR4/HLX	4
BP	GO:0051608	histamine transport	4/2486	12/18670	0.06424	0.2283	0.1789	BTK/SNAP23/LYN/ADCYAP1	4
BP	GO:0060391	positive regulation of SMAD protein signal transduction	4/2486	12/18670	0.06424	0.2283	0.1789	NUP93/TGFB1/DAB2/RBPMS	4
BP	GO:0071481	cellular response to X-ray	4/2486	12/18670	0.06424	0.2283	0.1789	XRCC6/NIPBL/SFRP2/SFRP1	4
BP	GO:0071679	commissural neuron axon guidance	4/2486	12/18670	0.06424	0.2283	0.1789	NRP1/NFIB/SMO/EPHB2	4
BP	GO:0071712	ER-associated misfolded protein catabolic process	4/2486	12/18670	0.06424	0.2283	0.1789	SDF2L1/DERL1/VCP/SDF2	4
BP	GO:0099638	endosome to plasma membrane protein transport	4/2486	12/18670	0.06424	0.2283	0.1789	GRIP1/GRIP2/GRASP/RAB8A	4
BP	GO:1901387	positive regulation of voltage-gated calcium channel activity	4/2486	12/18670	0.06424	0.2283	0.1789	FGF14/CACNB3/STAC/STAC2	4
BP	GO:1903909	regulation of receptor clustering	4/2486	12/18670	0.06424	0.2283	0.1789	CRKL/TGFB1/SSH1/PTN	4
BP	GO:0008645	hexose transmembrane transport	21/2486	112/18670	0.06435	0.2283	0.1789	GRB10/SLC2A5/CLIP3/RTN2/PRKCB/TNF/FABP5/SESN2/SLC2A8/IGF1/SLC45A1/ADIPOR2/SLC25A27/IRS2/SLC2A6/PRKAG2/IL1B/SORBS1/SLC2A10/SLC2A12/CAPN10	21
BP	GO:0050868	negative regulation of T cell activation	21/2486	112/18670	0.06435	0.2283	0.1789	ARG2/ARG1/IRF1/SMAD7/DLG1/TGFB1/PRDX2/FCGR2B/TWSG1/MIR21/ZC3H12A/HLX/CEACAM1/PDCD1LG2/IL2/TNFRSF14/GLI3/GPNMB/CD300A/SPN/RC3H1	21
BP	GO:0006869	lipid transport	59/2486	365/18670	0.06453	0.2283	0.1789	CLU/ITGB3/OSBP/GRAMD1B/LCN12/PPARG/OSBPL6/INHBA/NFKBIA/RFT1/CPT1C/GHRL/PLEKHA3/OSBP2/APOF/CYP4F2/SORL1/C2CD2L/PLA2G5/TEX2/SLC10A2/ACE/ABCA4/MSR1/CLN8/BDKRB2/APOC1/SIRT1/SPP1/P2RX7/OSBPL9/EGF/TNFRSF11A/HNRNPK/CEACAM1/IRS2/AGTR1/ABCA9/SLC10A7/C1QTNF1/PRKAG2/MFSD2A/IL1B/PLA2G2A/GLTP/STARD5/SLCO2A1/APOLD1/NCOA2/CAV1/TRIAP1/FZD4/PLTP/GRAMD1C/SLCO2B1/NR1H4/FABP3/APOL3/NCOA1	59
BP	GO:1903522	regulation of blood circulation	49/2486	297/18670	0.06466	0.2283	0.1789	SRI/SCN1B/FGF13/ITPR1/CACNA2D2/MYL4/SMAD7/DLG1/GHRL/TGFB2/ATP1B2/TPM1/CACNB3/ACE/ADRA2A/GJA5/MIR21/ZC3H12A/THRB/PDE4B/BDKRB2/EDN3/ASPH/JUP/GCH1/EGFR/KCND3/NOS3/STC1/SLC1A1/KCNA5/AGTR1/CACNA2D3/HRH1/IL2/FXYD1/NUP155/KCNK3/TBX2/KCNK6/FKBP1B/ANK2/OXTR/FLNA/RYR2/CAV1/DMD/KCNK1/ADORA3	49
BP	GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	5/2486	17/18670	0.0651	0.2283	0.1789	ACVR1/HEYL/TGFB2/NOTCH1/MSX1	5
BP	GO:0006825	copper ion transport	5/2486	17/18670	0.0651	0.2283	0.1789	ATP7B/FKBP4/STEAP2/CP/HEPH	5
BP	GO:0007076	mitotic chromosome condensation	5/2486	17/18670	0.0651	0.2283	0.1789	AKAP8L/NIPBL/NCAPG/PHF13/AKAP8	5
BP	GO:0010224	response to UV-B	5/2486	17/18670	0.0651	0.2283	0.1789	MME/RELA/IL12A/MFAP4/HYAL1	5
BP	GO:0010744	positive regulation of macrophage derived foam cell differentiation	5/2486	17/18670	0.0651	0.2283	0.1789	CSF1/LPL/MSR1/AGTR1/PLA2G2A	5
BP	GO:0016254	preassembly of GPI anchor in ER membrane	5/2486	17/18670	0.0651	0.2283	0.1789	PIGH/PIGX/PIGA/PIGY/PIGL	5
BP	GO:0030322	stabilization of membrane potential	5/2486	17/18670	0.0651	0.2283	0.1789	KCNK17/KCNK10/KCNK3/KCNK6/KCNK1	5
BP	GO:0031649	heat generation	5/2486	17/18670	0.0651	0.2283	0.1789	EDNRB/TNF/TNFRSF11A/IL1B/ABAT	5
BP	GO:0033599	regulation of mammary gland epithelial cell proliferation	5/2486	17/18670	0.0651	0.2283	0.1789	IQGAP3/PHB2/CCND1/RREB1/MST1	5
BP	GO:0035855	megakaryocyte development	5/2486	17/18670	0.0651	0.2283	0.1789	SH2B3/EP300/WASF2/TAL1/FLI1	5
BP	GO:0035988	chondrocyte proliferation	5/2486	17/18670	0.0651	0.2283	0.1789	LTF/MIR21/STC1/DDR2/SIX2	5
BP	GO:0042249	establishment of planar polarity of embryonic epithelium	5/2486	17/18670	0.0651	0.2283	0.1789	SFRP2/SEC24B/CTHRC1/SFRP1/WNT5A	5
BP	GO:0042268	regulation of cytolysis	5/2486	17/18670	0.0651	0.2283	0.1789	RRAGA/PGLYRP1/TGFB1/P2RX7/CFHR2	5
BP	GO:0042994	cytoplasmic sequestering of transcription factor	5/2486	17/18670	0.0651	0.2283	0.1789	SRI/KEAP1/NFKBIA/NFKBIE/G3BP2	5
BP	GO:0043373	CD4-positive, alpha-beta T cell lineage commitment	5/2486	17/18670	0.0651	0.2283	0.1789	IRF4/IL23R/BATF/MTOR/SPN	5
BP	GO:0043968	histone H2A acetylation	5/2486	17/18670	0.0651	0.2283	0.1789	ING3/TRRAP/MORF4L2/EP400/EPC1	5
BP	GO:0051818	disruption of cells of other organism involved in symbiotic interaction	5/2486	17/18670	0.0651	0.2283	0.1789	CTSG/ARG1/ELANE/CAMP/CXCL6	5
BP	GO:0061323	cell proliferation involved in heart morphogenesis	5/2486	17/18670	0.0651	0.2283	0.1789	TBX5/HES1/SIX1/SOX9/NOTCH1	5
BP	GO:1902931	negative regulation of alcohol biosynthetic process	5/2486	17/18670	0.0651	0.2283	0.1789	ERLIN1/BMP2/ERLIN2/REST/DKK3	5
BP	GO:1903209	positive regulation of oxidative stress-induced cell death	5/2486	17/18670	0.0651	0.2283	0.1789	SFPQ/FBXW7/MMP3/MCL1/REST	5
BP	GO:2000136	regulation of cell proliferation involved in heart morphogenesis	5/2486	17/18670	0.0651	0.2283	0.1789	TBX5/HES1/SIX1/SOX9/NOTCH1	5
BP	GO:0009308	amine metabolic process	25/2486	138/18670	0.06606	0.2314	0.1814	PSMD14/PSMD12/AMD1/SNCA/PSMD7/PSMB5/TRH/MAOA/MIR21/AOC3/NAAA/INMT/GDPD1/PSMB7/AADAT/PSMD1/PSMD9/NR4A2/AZIN1/SULT1C2/PSME1/NR1H4/ALDH7A1/NQO1/ABAT	25
BP	GO:0046631	alpha-beta T cell activation	25/2486	138/18670	0.06606	0.2314	0.1814	ARG2/IRF1/SMAD7/CD83/TWSG1/MIR21/ZC3H12A/IRF4/NFKBIZ/HLX/PTGER4/IL23R/BATF/CDH26/IL12A/TMEM98/IL2/TNFRSF14/GLI3/CD300A/MTOR/SPN/RC3H1/PTPRC/RSAD2	25
BP	GO:0010876	lipid localization	64/2486	400/18670	0.06647	0.2327	0.1824	CLU/ITGB3/OSBP/GRAMD1B/LCN12/PPARG/OSBPL6/INHBA/NFKBIA/RFT1/CPT1C/TNF/LPL/GHRL/PLEKHA3/OSBP2/APOF/CYP4F2/SORL1/C2CD2L/PLA2G5/TEX2/SLC10A2/ACE/FBXW7/ZC3H12A/ABCA4/MSR1/CLN8/BDKRB2/APOC1/SIRT1/SPP1/P2RX7/OSBPL9/EGF/TNFRSF11A/HNRNPK/CEACAM1/IRS2/AGTR1/ABCA9/SLC10A7/C1QTNF1/BSCL2/PRKAG2/MFSD2A/IL1B/PLA2G2A/GLTP/STARD5/SLCO2A1/APOLD1/NCOA2/CAV1/TRIAP1/FZD4/PLTP/GRAMD1C/SLCO2B1/NR1H4/FABP3/APOL3/NCOA1	64
BP	GO:0032872	regulation of stress-activated MAPK cascade	40/2486	237/18670	0.06658	0.233	0.1826	MMP8/TNF/DLG1/DUSP10/DNAJA1/TGFB2/PINK1/TRAF4/ITCH/PPEF2/FCGR2B/ERN1/ZC3H12A/IGF1R/BMP2/TRAF6/MAP3K2/EGFR/CYLD/SFRP2/SAMD5/MAP3K5/TPD52L1/PLCB1/TNFRSF11A/FZD10/MID1/IL1B/CCL21/SFRP1/FZD5/PDCD10/WNT5A/TLR9/IL26/DUSP1/MAP3K3/FZD4/PER1/RASSF2	40
BP	GO:1902229	regulation of intrinsic apoptotic signaling pathway in response to DNA damage	9/2486	39/18670	0.06665	0.2331	0.1827	CLU/MUC1/SIRT1/BCL2L1/SFRP2/SKIL/CXCL12/HNRNPK/TRIAP1	9
BP	GO:0042098	T cell proliferation	32/2486	184/18670	0.06722	0.2349	0.1841	HLA-DPB1/ARG2/FADD/ARG1/IRF1/DLG1/TGFB1/IGFBP2/PRDX2/CD276/HES1/TWSG1/MIR21/TRAF6/IL23R/P2RX7/IGF1/MSN/PDCD1LG2/IL12A/IL2/TNFRSF14/IL1B/FKBP1B/PPP3CB/GPNMB/SPN/RC3H1/PTPRC/CORO1A/DOCK8/CD151	32
BP	GO:0042866	pyruvate biosynthetic process	22/2486	119/18670	0.0675	0.2358	0.1848	SLC4A1/NUP93/PFKFB2/DHTKD1/ZBTB7A/NUP50/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/RAE1/NUP188/NUP160/NUP54/NUP214/NUP155/FOXK2/NUPR1/SLC2A6/PRKAG2/PFKP	22
BP	GO:0001707	mesoderm formation	15/2486	75/18670	0.0677	0.2362	0.1851	ITGB3/ACVR1/INHBA/TAL1/KDM6B/TWSG1/SMAD1/FOXC1/SFRP2/ITGA3/KLF4/HOXA11/WNT5A/SIX2/ITGA2	15
BP	GO:0007422	peripheral nervous system development	15/2486	75/18670	0.0677	0.2362	0.1851	SIRT2/NTF3/EDNRB/MPP5/BDNF/PARD3/NEFH/NTRK2/RELA/LGI4/POU4F1/GPC1/SH3TC2/ETV1/HOXD9	15
BP	GO:0070661	leukocyte proliferation	49/2486	298/18670	0.06775	0.2363	0.1852	CLU/INPP5D/HLA-DPB1/TNFAIP3/ARG2/FADD/ARG1/CSF1/IRF1/DLG1/TGFB1/IGFBP2/PRDX2/CD276/HES1/ACE/FCGR2B/CX3CL1/TWSG1/MIR21/BTK/TRAF6/IL23R/P2RX7/IGF1/MSN/IRS2/PDCD1LG2/IL12A/IL2/TNFRSF14/GAPT/IL1B/FKBP1B/IL33/TREM2/PPP3CB/GPNMB/VAV3/TLR9/CCL8/CD300A/LYN/SPN/RC3H1/PTPRC/CORO1A/DOCK8/CD151	49
BP	GO:0006937	regulation of muscle contraction	30/2486	171/18670	0.06788	0.2363	0.1852	SRI/MYL9/CTTN/FGF13/SMAD7/DLG1/GHRL/TPM1/TACR1/ADRA2A/GJA5/MIR21/ZC3H12A/PDE4B/JUP/CALCRL/STC1/NPNT/KCNMA1/KCNA1/FKBP1B/HSPB6/ANK2/OXTR/FLNA/RYR2/CAV1/ITGA2/DMD/ABAT	30
BP	GO:0016241	regulation of macroautophagy	30/2486	171/18670	0.06788	0.2363	0.1852	RRAGA/SCFD1/VPS13C/ATP6V1E1/PINK1/ERN1/LARP1/ATP6V0A2/RAB3GAP2/SIRT1/SESN2/SMCR8/UCHL1/FYCO1/WAC/SESN3/MTM1/NUPR1/LRSAM1/PRKAG2/RAB12/CDK5R1/UVRAG/DCN/VPS26B/MTOR/KDR/GPSM1/HSPB8/SCOC	30
BP	GO:0060401	cytosolic calcium ion transport	30/2486	171/18670	0.06788	0.2363	0.1852	SRI/PDPK1/ITPR1/SNCA/MCOLN3/NOL3/TGFB1/CACNB3/DIAPH1/FAM155A/CX3CL1/DDIT3/P2RX7/PML/PLCB2/PLCB1/RAMP3/APLNR/IBTK/FKBP1B/CCL21/THY1/ANK2/RYR2/CAV1/LYN/BAK1/DMD/PTPRC/CORO1A	30
BP	GO:0045995	regulation of embryonic development	24/2486	132/18670	0.06822	0.2374	0.1861	MBP/MYADM/GATA1/NIPBL/TDG/HES1/CLASP2/SFRP2/TGIF2/IGF1/SIX1/PLCB1/PHLDB2/STK4/SULF1/SEC24B/KLF4/COL5A1/TBX2/NOTCH1/SFRP1/WNT5A/CLASP1/COL5A2	24
BP	GO:0048538	thymus development	10/2486	45/18670	0.06846	0.2378	0.1864	FADD/PBX1/CRKL/PRDX2/HES1/RAF1/SIX1/JARID2/TBX1/HOXA3	10
BP	GO:0090278	negative regulation of peptide hormone secretion	10/2486	45/18670	0.06846	0.2378	0.1864	SYTL4/GHRL/ADRA2A/JAGN1/BMP8A/FKBP1B/SFRP1/PSMD9/REST/MIDN	10
BP	GO:1900274	regulation of phospholipase C activity	10/2486	45/18670	0.06846	0.2378	0.1864	NTF3/ARHGAP6/BDNF/FLT1/P2RY12/EGFR/NTRK2/PLCB2/PDGFRA/PDGFRB	10
BP	GO:0046622	positive regulation of organ growth	13/2486	63/18670	0.06927	0.2396	0.1878	TBX5/CACNA2D2/SERP1/HLX/IGF1/MIR17HG/SMO/TBX2/NOTCH1/YAP1/ZFPM2/MTOR/PIN1	13
BP	GO:0007566	embryo implantation	11/2486	51/18670	0.06934	0.2396	0.1878	ARID1A/FKBP4/MIR21/SPP1/STC1/RPL29/MMP9/EMP2/IL1B/FBLN1/STC2	11
BP	GO:0048641	regulation of skeletal muscle tissue development	11/2486	51/18670	0.06934	0.2396	0.1878	TWIST1/AKIRIN1/TGFB1/CYP26B1/SIX1/NR1D2/CDON/MTM1/SHOX2/GPC1/TBX1	11
BP	GO:0050999	regulation of nitric-oxide synthase activity	11/2486	51/18670	0.06934	0.2396	0.1878	DDAH1/TNF/CYGB/HSP90AA1/GCH1/EGFR/NOS3/ACVR2A/NOSTRIN/IL1B/CAV1	11
BP	GO:0001702	gastrulation with mouth forming second	7/2486	28/18670	0.06953	0.2396	0.1878	LRP5L/ACVR1/LDB1/ACVR2A/FRS2/WNT5A/LRP5	7
BP	GO:0001958	endochondral ossification	7/2486	28/18670	0.06953	0.2396	0.1878	MEF2D/TMEM119/SMPD3/FOXC1/FGF18/ALPL/TEK	7
BP	GO:0018146	keratan sulfate biosynthetic process	7/2486	28/18670	0.06953	0.2396	0.1878	CHST1/B4GALT2/ACAN/OGN/FMOD/PRELP/B4GALT4	7
BP	GO:0036075	replacement ossification	7/2486	28/18670	0.06953	0.2396	0.1878	MEF2D/TMEM119/SMPD3/FOXC1/FGF18/ALPL/TEK	7
BP	GO:0051647	nucleus localization	7/2486	28/18670	0.06953	0.2396	0.1878	SLC9A3R1/TRIM58/TMEM201/MYH10/SLIT1/DCTN4/SUN2	7
BP	GO:0060512	prostate gland morphogenesis	7/2486	28/18670	0.06953	0.2396	0.1878	SULF1/FRS2/SOX9/NOTCH1/SFRP1/WNT5A/TNC	7
BP	GO:0070076	histone lysine demethylation	7/2486	28/18670	0.06953	0.2396	0.1878	UTY/KDM5D/KDM6B/HSF4/KDM2A/JMJD1C/JARID2	7
BP	GO:0043244	regulation of protein complex disassembly	21/2486	113/18670	0.06953	0.2396	0.1878	EPS8/FGF13/EIF5A/TMOD1/NAV3/APC/TNF/CLASP2/IGF1R/ASPH/SMCR8/AVIL/FYCO1/TTBK2/LMOD1/PLEKHH2/MID1/CAPZA1/NES/UVRAG/CLASP1	21
BP	GO:0060964	regulation of gene silencing by miRNA	21/2486	113/18670	0.06953	0.2396	0.1878	PPARG/NUP93/FXR1/DHX9/TGFB1/ZFP36/ZC3H12A/NUP50/EGFR/POLR2G/NEAT1/NUP153/NUP210/RAE1/NUP188/NUP160/NUP54/NUP214/ZC3H10/NUP155/POLR2D	21
BP	GO:0043525	positive regulation of neuron apoptotic process	12/2486	57/18670	0.06955	0.2396	0.1878	TNF/JUN/TGFB2/SRPK2/FBXW7/DDIT3/MCL1/NUPR1/CDK5R1/PAK3/NQO1/PIN1	12
BP	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	12/2486	57/18670	0.06955	0.2396	0.1878	SRI/LRP5L/CDK16/GHRL/C2CD2L/ADRA2A/JAGN1/STX4/FKBP1B/PPP3CB/NR1H4/LRP5	12
BP	GO:0007204	positive regulation of cytosolic calcium ion concentration	52/2486	319/18670	0.06966	0.2399	0.188	SRI/PDPK1/ITPR1/EDNRB/SNCA/MCOLN3/NOL3/SPPL3/GHRL/TGFB1/LPAR6/CACNB3/TACR1/DIAPH1/FAM155A/CX3CL1/CXCR1/BDKRB2/GPR4/PTGER4/DDIT3/P2RX7/LPAR4/MCHR1/GPR35/PML/PLCB2/PTH1R/PTGFR/PLCB1/PDGFRA/AGTR1/C1QTNF1/IL2/RAMP3/APLNR/CIB2/IBTK/FKBP1B/CCL21/THY1/ANK2/OXTR/P2RY8/RYR2/CAV1/LYN/BAK1/ADCYAP1/DMD/PTPRC/CORO1A	52
BP	GO:0015849	organic acid transport	54/2486	333/18670	0.07078	0.2434	0.1908	SLC15A4/LCN12/SLC6A8/SLC9A3R1/PPARG/ARG1/SNCA/CPT1C/SLC1A3/NFKBIE/CYP4F2/TRH/PLA2G5/SLC10A2/ACE/STXBP1/LRRC8A/CLN8/BDKRB2/NTRK2/P2RX7/SLC26A10/PDPN/SLC1A1/TNFRSF11A/CEACAM1/IRS2/SLC26A6/SLC7A3/SLC7A9/SLC10A7/SLC32A1/SLC16A4/PRKAG2/MFSD2A/IL1B/PLA2G2A/STARD5/SLCO2A1/SLC23A1/LRRC8E/NCOA2/SLC26A8/SLC38A4/SLC17A5/SLCO2B1/UNC13B/GIPC1/NR1H4/FABP3/SLC25A29/SLC6A1/ABAT/NCOA1	54
BP	GO:0046942	carboxylic acid transport	54/2486	333/18670	0.07078	0.2434	0.1908	SLC15A4/LCN12/SLC6A8/SLC9A3R1/PPARG/ARG1/SNCA/CPT1C/SLC1A3/NFKBIE/CYP4F2/TRH/PLA2G5/SLC10A2/ACE/STXBP1/LRRC8A/CLN8/BDKRB2/NTRK2/P2RX7/SLC26A10/PDPN/SLC1A1/TNFRSF11A/CEACAM1/IRS2/SLC26A6/SLC7A3/SLC7A9/SLC10A7/SLC32A1/SLC16A4/PRKAG2/MFSD2A/IL1B/PLA2G2A/STARD5/SLCO2A1/SLC23A1/LRRC8E/NCOA2/SLC26A8/SLC38A4/SLC17A5/SLCO2B1/UNC13B/GIPC1/NR1H4/FABP3/SLC25A29/SLC6A1/ABAT/NCOA1	54
BP	GO:0043506	regulation of JUN kinase activity	17/2486	88/18670	0.07133	0.2449	0.192	TNF/DUSP10/DNAJA1/PPEF2/ERN1/TRAF6/MAP3K2/SFRP2/SAMD5/MAP3K5/TNFRSF11A/FZD10/SFRP1/FZD5/WNT5A/TLR9/FZD4	17
BP	GO:0048644	muscle organ morphogenesis	17/2486	88/18670	0.07133	0.2449	0.192	SMAD7/TGFB2/TGFB1/TPM1/SERP1/ADARB1/FOXC1/BMP2/OBSL1/UBE4B/POU4F1/NOTCH1/SHOX2/ZFPM2/WNT5A/RYR2/TBX1	17
BP	GO:1903557	positive regulation of tumor necrosis factor superfamily cytokine production	17/2486	88/18670	0.07133	0.2449	0.192	CLU/ORM1/MMP8/FADD/ARFGEF2/TWIST1/LPL/DHX9/NFATC4/IFIH1/HSPB1/FZD5/WNT5A/TLR9/SPN/FRMD8/PTPRC	17
BP	GO:0048839	inner ear development	33/2486	192/18670	0.07288	0.2497	0.1957	C1QB/SPRY2/MAF/SLC9A3R1/SPARC/MCOLN3/FOXI1/TGFB2/TGFB1/PVALB/HES1/JAG2/BMP2/SOBP/SIX1/SLC25A27/GJB6/SEC24B/PRRX1/KCNK3/PDGFRB/SOX9/NOTCH1/ALDH1A3/GLI3/CTHRC1/WNT5A/ROR1/LRIG3/TBX1/ANP32B/EPHB2/MYO15A	33
BP	GO:0016925	protein sumoylation	16/2486	82/18670	0.07293	0.2497	0.1957	BCL11A/NUP93/CBX4/NUP50/IFIH1/SENP6/RELA/NUP153/NUP210/RAE1/NUP188/NUP160/NUP54/NUP214/NUP155/RANGAP1	16
BP	GO:0032637	interleukin-8 production	16/2486	82/18670	0.07293	0.2497	0.1957	CHI3L1/FADD/TNF/BCL10/CD244/ELANE/DDIT3/KLF4/AFAP1L2/OTUD7B/IL1B/IL17D/SSC5D/WNT5A/TLR9/PTPRC	16
BP	GO:0032642	regulation of chemokine production	16/2486	82/18670	0.07293	0.2497	0.1957	ARG2/MBP/TNF/TWIST1/LPL/ELANE/CXCL6/KLF4/IL1B/IL33/TREM2/WNT5A/TLR9/POSTN/ADCYAP1/NR1H4	16
BP	GO:0060415	muscle tissue morphogenesis	16/2486	82/18670	0.07293	0.2497	0.1957	SMAD7/TGFB2/TGFB1/TPM1/ADARB1/FOXC1/BMP2/OBSL1/UBE4B/POU4F1/NOTCH1/SHOX2/ZFPM2/WNT5A/RYR2/TBX1	16
BP	GO:0006888	ER to Golgi vesicle-mediated transport	36/2486	212/18670	0.07303	0.2499	0.1959	PROS1/COG3/TRAPPC10/SCFD1/PEF1/ARF1/PROC/CNIH3/CD59/COPB2/GAS1/DYNC1I1/ACTR10/SORL1/HYOU1/GAS6/TFG/TMEM115/SEC16A/F8/VCP/ANK1/BET1/LMAN1L/SEC24B/WHAMM/CAPZA1/GOSR1/RAB12/KDELR3/ANK2/RNF139/ARFGAP2/DYNLL2/DCTN4/COPZ2	36
BP	GO:0071333	cellular response to glucose stimulus	24/2486	133/18670	0.07317	0.2501	0.1961	SRI/LRP5L/TRA2B/CDK16/GHRL/RAB11FIP5/C2CD2L/GAS6/ERN1/ADRA2A/RAF1/IGF1R/JAGN1/GJB6/IRS2/POLG/STX4/FKBP1B/PPP3CB/NOX4/UNC13B/NR1H4/LRP5/SIN3A	24
BP	GO:0045834	positive regulation of lipid metabolic process	26/2486	146/18670	0.07318	0.2501	0.1961	PPARG/TNF/TWIST1/FLT1/SCT/TGFB1/CREB1/SMPD3/P2RY12/APOC1/PDGFRA/CCDC3/IRS2/AGTR1/PDGFRB/IL1B/TEK/CCL21/SORBS1/VAV3/DGKZ/MTOR/LYN/NR1H4/FABP3/ELOVL5	26
BP	GO:0046545	development of primary female sexual characteristics	19/2486	101/18670	0.07365	0.2515	0.1971	INHBA/TAF4/TIPARP/FOXC1/SIRT1/BCL2L1/NOS3/PDGFRA/MMP19/NUPR1/SFRP1/ZFPM2/SLIT2/ADCYAP1/FZD4/HSPA5/EIF2B2/LHX8/ZNF830	19
BP	GO:1903426	regulation of reactive oxygen species biosynthetic process	19/2486	101/18670	0.07365	0.2515	0.1971	CLU/HBB/DDAH1/MMP8/ARG2/SLC25A33/SNCA/TNF/HSP90AA1/MIR21/ZC3H12A/ASS1/KLF4/CD34/ACP5/IL1B/HSP90AB1/CAV1/MTOR	19
BP	GO:0031128	developmental induction	8/2486	34/18670	0.07381	0.2515	0.1971	SPRY1/HIPK1/BMP2/SIX1/FRS2/SOX9/HOXA11/FZD5	8
BP	GO:0033120	positive regulation of RNA splicing	8/2486	34/18670	0.07381	0.2515	0.1971	TRA2B/RBM22/SF3B4/ERN1/RBM3/RBMXL1/TRA2A/RBMX	8
BP	GO:0098901	regulation of cardiac muscle cell action potential	8/2486	34/18670	0.07381	0.2515	0.1971	FGF13/DLG1/GJA5/JUP/ANK2/FLNA/RYR2/CAV1	8
BP	GO:0140115	export across plasma membrane	8/2486	34/18670	0.07381	0.2515	0.1971	DLG1/ATP1B2/MIR21/KCND3/KCNA5/FXYD1/KCNT2/KCNA3	8
BP	GO:0030177	positive regulation of Wnt signaling pathway	31/2486	179/18670	0.07393	0.2518	0.1973	PSMD14/PSMD12/TNFAIP3/FAM53B/PLEKHA4/PSMD7/PSMB5/DAAM2/PRDM15/BMP2/DAB2/JUP/EGFR/SFRP2/EGF/VCP/ZBED2/SULF1/SFRP4/PPM1A/RSPO3/PSMB7/YAP1/PSMD1/SFRP1/PSMD9/WNT5A/CAV1/PSME1/RNF220/PIN1	31
BP	GO:0061013	regulation of mRNA catabolic process	34/2486	199/18670	0.07436	0.2531	0.1984	PSMD14/PSMD12/PABPC4/CNOT8/YTHDF2/FXR1/DHX9/PSMD7/HNRNPM/PSMB5/TNRC6B/ZFP36/UBA52/LARP1/DCP2/ZC3H12A/EXOSC3/HSPB1/POLR2G/YWHAZ/NUP214/PSMB7/YBX1/PSMD1/BTG2/PSMD9/UBC/YTHDF3/CNOT7/MTOR/SET/PSME1/RC3H1/CNOT1	34
BP	GO:0042310	vasoconstriction	15/2486	76/18670	0.07442	0.2531	0.1984	EDNRB/ACE/ADRA2A/GJA5/MIR21/GRIP2/BDKRB2/EDN3/EGFR/KCNA5/AGTR1/HRH1/OXTR/CAV1/ACTA2	15
BP	GO:0042133	neurotransmitter metabolic process	27/2486	153/18670	0.07542	0.2552	0.2	CLU/HBB/DDAH1/MMP8/ARG2/DAGLB/TNF/SLC1A3/TRH/MAOA/HSP90AA1/ZC3H12A/GCH1/NOS3/GCAT/ASS1/KLF4/CD34/ACP5/IL1B/CPS1/HSP90AB1/CAV1/MTOR/ALDH7A1/NQO1/ABAT	27
BP	GO:0045807	positive regulation of endocytosis	27/2486	153/18670	0.07542	0.2552	0.2	CLU/NTF3/PPARG/ARF1/CLIP3/SNCA/TUB/TNF/C2/GAS6/FCGR2B/DAB2/EGF/HNRNPK/CBL/SFRP4/DNM1/IL1B/CD300LF/CCL21/TREM2/WNT5A/MAGI2/ITGA2/PTPRC/AXL/CD151	27
BP	GO:0007413	axonal fasciculation	6/2486	23/18670	0.07546	0.2552	0.2	NRCAM/NRP1/CDK5R1/NDN/NCAM2/EPHB2	6
BP	GO:0032703	negative regulation of interleukin-2 production	6/2486	23/18670	0.07546	0.2552	0.2	TNFAIP3/NAV3/ZFP36/CD34/PTPRC/NR1H4	6
BP	GO:0034695	response to prostaglandin E	6/2486	23/18670	0.07546	0.2552	0.2	PPARG/PTGER4/ADCY6/CCL21/SFRP1/AKAP8	6
BP	GO:0050995	negative regulation of lipid catabolic process	6/2486	23/18670	0.07546	0.2552	0.2	TNF/SORL1/ADRA2A/APOC1/BSCL2/IL1B	6
BP	GO:0071305	cellular response to vitamin D	6/2486	23/18670	0.07546	0.2552	0.2	KANK2/PHEX/TRIM24/PTN/SFRP1/TNC	6
BP	GO:0071425	hematopoietic stem cell proliferation	6/2486	23/18670	0.07546	0.2552	0.2	YTHDF2/ARIH2/ACE/SFRP2/CD34/WNT5A	6
BP	GO:0106030	neuron projection fasciculation	6/2486	23/18670	0.07546	0.2552	0.2	NRCAM/NRP1/CDK5R1/NDN/NCAM2/EPHB2	6
BP	GO:1900746	regulation of vascular endothelial growth factor signaling pathway	6/2486	23/18670	0.07546	0.2552	0.2	SPRY2/PTP4A3/SMOC2/MYO1C/DCN/CCBE1	6
BP	GO:0019882	antigen processing and presentation	38/2486	226/18670	0.07547	0.2552	0.2	CD1C/PSMD14/PSMD12/ITGB5/HLA-DPB1/KIF26A/ARF1/DYNC1I1/PSMD7/PDIA3/PSMB5/ACTR10/ACE/FCGR2B/TAPBPL/CD1B/YTHDF1/TRAF6/KIF4A/AP2A2/HLA-B/SEC24B/IDE/PSMB7/KIF2C/CAPZA1/SNAP23/PSMD1/CCL21/TREM2/PSMD9/CTSF/DYNLL2/PSME1/AP1S3/DCTN4/HLA-A/KLC1	38
BP	GO:0002702	positive regulation of production of molecular mediator of immune response	18/2486	95/18670	0.0757	0.2556	0.2004	TRIM6/BCL10/IL1R1/CD244/TGFB1/DDX21/EXOSC3/TRAF6/IL2/TNFRSF14/IL1B/STX4/IL33/FZD5/WNT5A/TLR9/PTPRC/RSAD2	18
BP	GO:0010517	regulation of phospholipase activity	14/2486	70/18670	0.07573	0.2556	0.2004	NTF3/ARHGAP6/PDPK1/BDNF/SNCA/FLT1/PLA2G5/P2RY12/EGFR/NTRK2/PLCB2/PDGFRA/AGTR1/PDGFRB	14
BP	GO:0034121	regulation of toll-like receptor signaling pathway	14/2486	70/18670	0.07573	0.2556	0.2004	PDPK1/TNFAIP3/OTUD4/IRF1/LTF/LILRA4/IRF4/RAB7B/CD300LF/TLR9/CD300A/CAV1/LYN/RSAD2	14
BP	GO:0001941	postsynaptic membrane organization	9/2486	40/18670	0.07628	0.2568	0.2013	CRKL/SSH1/PTN/CRIPT/MAGI2/NLGN4X/GLRB/EPHB2/SHANK3	9
BP	GO:0002369	T cell cytokine production	9/2486	40/18670	0.07628	0.2568	0.2013	ARG1/SMAD7/DLG1/IL1R1/TRAF6/IL12A/IL1B/FZD5/RSAD2	9
BP	GO:0009187	cyclic nucleotide metabolic process	9/2486	40/18670	0.07628	0.2568	0.2013	ADCY3/GUCY2D/ADCY7/ADCY4/PDE2A/PDE4B/ADCY6/AMPD2/PDE1A	9
BP	GO:0045124	regulation of bone resorption	9/2486	40/18670	0.07628	0.2568	0.2013	ITGB3/INPP5D/TNFAIP3/TMEM119/SPP1/EGFR/P2RX7/TNFRSF11A/PDK4	9
BP	GO:0072583	clathrin-dependent endocytosis	9/2486	40/18670	0.07628	0.2568	0.2013	ITGA4/UNC119/DAB2/FNBP1L/AP2A2/FCHSD2/FCHO1/INPP5F/SYT11	9
BP	GO:0097305	response to alcohol	39/2486	233/18670	0.07659	0.2577	0.202	ADCY3/GRAMD1B/PSMD14/EPS8/POLB/FOSB/PPARG/SPARC/INHBA/HPGD/ADCY7/CDO1/TGFB1/TRH/CCND1/LARP1/FOS/PTGER4/JUP/BCL2L1/ADCY6/PTGFR/CBL/AKR1C2/IL2/SMO/KLF4/CCL21/SFRP1/HMGCS1/AKAP8/SLIT2/BAK1/ADCYAP1/GRAMD1C/TNC/MGMT/NQO1/ABAT	39
BP	GO:0051346	negative regulation of hydrolase activity	73/2486	466/18670	0.07674	0.2581	0.2023	PROS1/SLPI/SPRY2/SPOCD1/SH2D4A/PPP1R15A/BAG4/RTKN/SNCA/TNF/CD109/LTF/NOL3/TGFB2/SORL1/SPRY1/IFI16/HERPUD1/GAS6/PCDH11X/DLG2/CEP192/MIR21/UBXN1/RAF1/APOC1/ANGPTL4/SIRT1/SERPING1/ECM1/NOS3/CCDC8/SFRP2/SEMA4D/SERPINH1/WFDC1/PTN/TFPI/MMP9/MAP2/WNT9A/FZD10/TIMP3/IFIT1/AQP1/TMEM225/FARP1/KLF4/SERPINB9/WFDC3/IFI6/SERPINA3/FKBP1B/TIMP4/IPO5/TLR9/ELL/PCIF1/SLIT2/ITIH2/TRIAP1/SET/ADCYAP1/STYXL1/A2M/GPSM1/SPINT2/CRYAB/ABCE1/LXN/CPEB2/RARRES1/NLRP7	73
BP	GO:0043550	regulation of lipid kinase activity	13/2486	64/18670	0.0768	0.2581	0.2023	SOCS7/FLT1/TGFB1/P2RY12/PDGFRA/KLF4/PDGFRB/TEK/CCL21/WDR91/VAV3/DGKZ/LYN	13
BP	GO:1901987	regulation of cell cycle phase transition	75/2486	480/18670	0.07701	0.2587	0.2028	MUC1/SIRT2/PSMD14/PSMD12/CRADD/CNOT8/CNOT4/EP300/RPS27L/SYF2/APC/PBX1/TGFB1/PSMD7/PSMB5/MTBP/PHB2/ANLN/KANK2/CDKN1C/FBXW7/CCND1/HSP90AA1/CTDSPL/CDKN2C/CEP192/MIR21/TPX2/MDM4/EGFR/HECW2/PML/CEP135/FOXN3/HAUS8/BUB1B/PLCB1/CDK2AP2/ODF2/CDC45/DBF4/KCNA5/ANAPC10/PLK3/PSMB7/KLF4/PLK1/UBE2C/PSMD1/BTG2/CDKN2B/PSMD9/GPNMB/MIR214/FAM107A/HAUS2/NDE1/DUSP1/CNOT7/SSNA1/TTK/CLASP1/TRIAP1/TNKS1BP1/TAF1/E2F8/PSME1/PRKAR2B/HYAL1/SIN3A/KIF14/NEK2/CNOT1/CUL1/ZNF830	75
BP	GO:0043300	regulation of leukocyte degranulation	10/2486	46/18670	0.0775	0.2594	0.2033	PDPK1/CD177/STXBP1/FCGR2B/C12orf4/CEACAM1/IL13RA2/STX4/CD300A/LYN	10
BP	GO:0043330	response to exogenous dsRNA	10/2486	46/18670	0.0775	0.2594	0.2033	NFKBIA/DHX9/DDX21/PQBP1/IFIH1/IFIT1/COLEC12/CAV1/RFTN2/ZCCHC3	10
BP	GO:0071675	regulation of mononuclear cell migration	10/2486	46/18670	0.0775	0.2594	0.2033	CSF1/TNF/AKIRIN1/TGFB1/RARRES2/CXCL12/PLCB1/DUSP1/SLIT2/LYN	10
BP	GO:0006754	ATP biosynthetic process	28/2486	160/18670	0.07751	0.2594	0.2033	SLC4A1/NUP93/TGFB1/PINK1/PFKFB2/LDHC/DHTKD1/FLCN/ZBTB7A/NUP50/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/VCP/RAE1/NUP188/NUP160/NUP54/NUP214/NUP155/FOXK2/NUPR1/SLC2A6/PRKAG2/TREM2/PFKP	28
BP	GO:0019229	regulation of vasoconstriction	12/2486	58/18670	0.07755	0.2594	0.2033	ACE/ADRA2A/GJA5/MIR21/BDKRB2/EDN3/EGFR/KCNA5/AGTR1/HRH1/OXTR/CAV1	12
BP	GO:0031663	lipopolysaccharide-mediated signaling pathway	12/2486	58/18670	0.07755	0.2594	0.2033	TNFAIP3/NFKBIA/TNF/BCL10/LTF/TGFB1/PRDX2/CX3CL1/TRAF6/NOS3/IL1B/LYN	12
BP	GO:0071385	cellular response to glucocorticoid stimulus	12/2486	58/18670	0.07755	0.2594	0.2033	ARG1/TGFB1/ZFP36/AKAP13/EGFR/STC1/ASS1/AQP1/NR3C1/REST/FAM107A/ADCYAP1	12
BP	GO:1904589	regulation of protein import	12/2486	58/18670	0.07755	0.2594	0.2033	RBM22/TGFB1/NOLC1/ZC3H12A/JUP/NUP54/SMO/GLI3/IPO5/FLNA/HCLS1/PDCD5	12
BP	GO:0050663	cytokine secretion	40/2486	240/18670	0.07764	0.2596	0.2034	CHI3L1/ORM1/MMP8/TNFAIP3/ARG2/MBP/MAPK11/TRIM6/TNF/TWIST1/LPL/GHRL/DHX9/CD244/GAS6/FCGR2B/CX3CL1/ZC3H12A/FN1/PTGER4/IFIH1/P2RX7/PML/TNFRSF14/CD34/NOTCH1/IL1B/IL33/FZD5/SSC5D/NLRP1/WNT5A/TLR9/IL26/LYN/POSTN/FRMD8/NR1H4/SYT11/NLRP7	40
BP	GO:0009620	response to fungus	11/2486	52/18670	0.07784	0.2597	0.2035	CTSG/ARG1/BCL10/LTF/TGFB1/ELANE/BTK/JAGN1/RARRES2/COTL1/BAK1	11
BP	GO:0046580	negative regulation of Ras protein signal transduction	11/2486	52/18670	0.07784	0.2597	0.2035	SPRY2/SCAI/TGFB2/SPRY1/FLCN/SPRY4/ITGA3/DLC1/TNFAIP1/MAPKAP1/EPHB2	11
BP	GO:0051438	regulation of ubiquitin-protein transferase activity	11/2486	52/18670	0.07784	0.2597	0.2035	FEM1A/SMAD7/PINK1/FBXW7/UBE2S/RPS2/PLK1/DTX3L/UBE2C/RPS7/PIN1	11
BP	GO:2000179	positive regulation of neural precursor cell proliferation	11/2486	52/18670	0.07784	0.2597	0.2035	VEGFC/CX3CL1/EGF/NAP1L1/CDON/SMO/NOTCH1/GLI3/NES/FLNA/LYN	11
BP	GO:0010212	response to ionizing radiation	26/2486	147/18670	0.07811	0.2603	0.204	POLB/XRCC6/POLE3/NIPBL/TGFB1/IFI16/CCND1/FBXO4/USP28/SIRT1/BCL2L1/SFRP2/PML/MTA1/CBL/YAP1/POLG/SFRP1/NOX4/BAK1/TNKS1BP1/HSPA5/MGMT/CRYAB/PTPRC/RNF8	26
BP	GO:0090263	positive regulation of canonical Wnt signaling pathway	26/2486	147/18670	0.07811	0.2603	0.204	PSMD14/PSMD12/FAM53B/PLEKHA4/PSMD7/PSMB5/DAAM2/PRDM15/JUP/EGFR/SFRP2/EGF/VCP/ZBED2/SFRP4/PPM1A/RSPO3/PSMB7/YAP1/PSMD1/SFRP1/PSMD9/CAV1/PSME1/RNF220/PIN1	26
BP	GO:0071346	cellular response to interferon-gamma	31/2486	180/18670	0.07839	0.2611	0.2046	HLA-DPB1/CAMK2G/PPARG/IRF8/ARG1/IRF1/STX8/TRIM21/STXBP1/CX3CL1/MT2A/PARP9/IRF4/CCL13/JAK1/PML/ASS1/HLA-B/SLC26A6/MID1/RAB7B/MYO1C/RAB12/STX4/CCL21/WNT5A/CCL8/VPS26B/HSP90AB1/CCL18/HLA-A	31
BP	GO:0000086	G2/M transition of mitotic cell cycle	41/2486	247/18670	0.07864	0.2618	0.2052	PSMD14/PSMD12/CIT/SYF2/PBX1/PSMD7/PSMB5/PPM1D/CCND1/HSP90AA1/CEP192/MIR21/TPX2/TPD52L1/CEP135/FOXN3/HAUS8/PLCB1/ODF2/CCNY/MELK/PLK3/PSMB7/PLK1/PSMD1/KHDRBS1/CDKN2B/PSMD9/NES/SKP2/HAUS2/NDE1/SSNA1/CLASP1/PSME1/PRKAR2B/SIN3A/KIF14/NEK2/CUL1/ZNF830	41
BP	GO:0042509	regulation of tyrosine phosphorylation of STAT protein	16/2486	83/18670	0.07968	0.2646	0.2074	SH2B3/TNF/PPP2CA/HES1/CRLF1/PARP9/IL23R/IGF1/IL12A/IL2/CNOT7/CAV1/HCLS1/INPP5F/LYN/GHR	16
BP	GO:0010522	regulation of calcium ion transport into cytosol	19/2486	102/18670	0.07971	0.2646	0.2074	SRI/PDPK1/SNCA/TGFB1/DIAPH1/CX3CL1/P2RX7/PML/RAMP3/APLNR/FKBP1B/THY1/ANK2/RYR2/CAV1/LYN/BAK1/DMD/CORO1A	19
BP	GO:0021549	cerebellum development	19/2486	102/18670	0.07971	0.2646	0.2074	FAIM2/HERC1/B4GALT2/CRKL/LDB1/FCGR2B/FOXC1/PTN/AGTPBP1/TTBK2/SMO/CDK5R1/NLGN4X/MYH10/FZD4/HSPA5/KIF14/ABAT/NCOA1	19
BP	GO:0098869	cellular oxidant detoxification	19/2486	102/18670	0.07971	0.2646	0.2074	HBB/HBD/TNF/PRDX2/CYGB/PXDN/NXN/HBM/MIR21/SESN2/LOXHD1/GCH1/GSTT1/NOS3/HP/GPX8/HBQ1/SOD3/NQO1	19
BP	GO:2000379	positive regulation of reactive oxygen species metabolic process	19/2486	102/18670	0.07971	0.2646	0.2074	CLU/HBB/DDAH1/MMP8/CD177/SNCA/TNF/TGFB1/HSP90AA1/ZC3H12A/EGFR/ASS1/AGTR1/KLF4/PDGFRB/IL1B/NOX4/HSP90AB1/MTOR	19
BP	GO:0032984	protein-containing complex disassembly	53/2486	329/18670	0.07992	0.265	0.2077	EPS8/ARID1A/GABARAPL2/FGF13/MAP1LC3A/EIF5A/TMOD1/MRPL36/PELO/NAV3/APC/TNF/MRPL44/TECPR1/MRPL48/CLASP2/DENR/SMARCC1/IGF1R/MRPL15/MRPL20/CHMP1B/ASPH/SMCR8/AVIL/MRPS28/FYCO1/VCP/MRPS14/CSNK1A1/TTBK2/LMOD1/PLEKHH2/MID1/MRPL18/KIF2C/CAPZA1/ZFAND1/NES/FZD5/UVRAG/MRPL13/CAV1/MRPL21/MRPL17/CLASP1/SET/MRPL54/N6AMT1/ABCE1/KLC1/MRPL2/GFM2	53
BP	GO:1901343	negative regulation of vasculature development	32/2486	187/18670	0.08002	0.265	0.2077	SPRY2/PPARG/SPARC/GTF2I/GHRL/TGFB2/MIR21/FOXC1/GPR4/MMRN2/THBS4/ECSCR/PML/ADAMTS9/CARD10/VASH1/PTN/COL4A2/SULF1/MEOX2/KLF4/CREB3L1/TIE1/NOTCH1/TEK/ANGPT2/PDCD10/MIR214/DCN/SEMA3E/FOXJ2/NFATC3	32
BP	GO:0001911	negative regulation of leukocyte mediated cytotoxicity	5/2486	18/18670	0.08064	0.265	0.2077	FCGR2B/CEACAM1/SERPINB9/PPP3CB/PTPRC	5
BP	GO:0006607	NLS-bearing protein import into nucleus	5/2486	18/18670	0.08064	0.265	0.2077	KPNA1/KPNA3/NUP54/IPO5/KPNA4	5
BP	GO:0007250	activation of NF-kappaB-inducing kinase activity	5/2486	18/18670	0.08064	0.265	0.2077	CHI3L1/TRAF4/TRAF6/CARD10/ZFP91	5
BP	GO:0007597	blood coagulation, intrinsic pathway	5/2486	18/18670	0.08064	0.265	0.2077	VWF/SERPING1/F8/GP1BA/A2M	5
BP	GO:0016446	somatic hypermutation of immunoglobulin genes	5/2486	18/18670	0.08064	0.265	0.2077	MSH6/POLB/SAMHD1/EXO1/MCM3AP	5
BP	GO:0031065	positive regulation of histone deacetylation	5/2486	18/18670	0.08064	0.265	0.2077	AKAP8L/NIPBL/TGFB1/PINK1/AKAP8	5
BP	GO:0051023	regulation of immunoglobulin secretion	5/2486	18/18670	0.08064	0.265	0.2077	TNF/TRAF6/IL2/STX4/IL33	5
BP	GO:0051895	negative regulation of focal adhesion assembly	5/2486	18/18670	0.08064	0.265	0.2077	ARHGAP6/CLASP2/PHLDB2/FAM107A/DLC1	5
BP	GO:0051957	positive regulation of amino acid transport	5/2486	18/18670	0.08064	0.265	0.2077	TRH/STXBP1/P2RX7/SLC6A1/ABAT	5
BP	GO:0070633	transepithelial transport	5/2486	18/18670	0.08064	0.265	0.2077	ITPR1/EDNRB/SLC26A6/AQP1/SLC23A1	5
BP	GO:0072574	hepatocyte proliferation	5/2486	18/18670	0.08064	0.265	0.2077	TNFAIP3/LIMS2/FBXW7/PTN/CEACAM1	5
BP	GO:0072575	epithelial cell proliferation involved in liver morphogenesis	5/2486	18/18670	0.08064	0.265	0.2077	TNFAIP3/LIMS2/FBXW7/PTN/CEACAM1	5
BP	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	5/2486	18/18670	0.08064	0.265	0.2077	TGFB1/SIX1/HOXB7/SMO/SOX9	5
BP	GO:0090196	regulation of chemokine secretion	5/2486	18/18670	0.08064	0.265	0.2077	MBP/TNF/LPL/IL33/POSTN	5
BP	GO:1905276	regulation of epithelial tube formation	5/2486	18/18670	0.08064	0.265	0.2077	SFRP2/SIX1/SEC24B/SFRP1/WNT5A	5
BP	GO:2000193	positive regulation of fatty acid transport	5/2486	18/18670	0.08064	0.265	0.2077	CYP4F2/P2RX7/TNFRSF11A/IL1B/FABP3	5
BP	GO:2000757	negative regulation of peptidyl-lysine acetylation	5/2486	18/18670	0.08064	0.265	0.2077	SNCA/TWIST1/SIRT1/SET/SIN3A	5
BP	GO:0008344	adult locomotory behavior	15/2486	77/18670	0.08156	0.2666	0.2089	EPS8/NTAN1/TMOD1/SNCA/FXN/TRH/CLN8/DMRT3/UCHL1/CXCL12/LGI4/NR4A2/INPP5F/GLRB/HOXD9	15
BP	GO:0000303	response to superoxide	7/2486	29/18670	0.08157	0.2666	0.2089	TNF/PRDX2/MIR21/GCH1/NOS3/SOD3/NQO1	7
BP	GO:0010644	cell communication by electrical coupling	7/2486	29/18670	0.08157	0.2666	0.2089	SRI/ATP1B2/GJA5/KCNA1/FKBP1B/RYR2/CAV1	7
BP	GO:0031114	regulation of microtubule depolymerization	7/2486	29/18670	0.08157	0.2666	0.2089	FGF13/NAV3/APC/CLASP2/TTBK2/MID1/CLASP1	7
BP	GO:0033014	tetrapyrrole biosynthetic process	7/2486	29/18670	0.08157	0.2666	0.2089	ALAS2/UROD/FXN/IREB2/ABCB6/MMACHC/ALAS1	7
BP	GO:0034367	protein-containing complex remodeling	7/2486	29/18670	0.08157	0.2666	0.2089	LPL/APOC1/GPIHBP1/AGTR1/GTF2E1/PLA2G2A/PLTP	7
BP	GO:0035025	positive regulation of Rho protein signal transduction	7/2486	29/18670	0.08157	0.2666	0.2089	LPAR6/AKAP13/GPR4/LPAR4/GPR35/PDGFRB/P2RY8	7
BP	GO:0044788	modulation by host of viral process	7/2486	29/18670	0.08157	0.2666	0.2089	IFI27/STOM/EIF2AK4/CAV2/LTF/ZC3H12A/CCL8	7
BP	GO:0050855	regulation of B cell receptor signaling pathway	7/2486	29/18670	0.08157	0.2666	0.2089	LPXN/PRKCB/ELF2/FCGR2B/CD300A/CMTM3/LYN	7
BP	GO:0061099	negative regulation of protein tyrosine kinase activity	7/2486	29/18670	0.08157	0.2666	0.2089	SH3BP5L/CHMP6/CBL/IBTK/THY1/CAV1/PTPRC	7
BP	GO:2000515	negative regulation of CD4-positive, alpha-beta T cell activation	7/2486	29/18670	0.08157	0.2666	0.2089	ARG2/SMAD7/TWSG1/ZC3H12A/HLX/IL2/RC3H1	7
BP	GO:0015711	organic anion transport	75/2486	482/18670	0.08257	0.2688	0.2107	HBB/SLC15A4/LCN12/SLC6A8/SLC9A3R1/PPARG/SLC4A1/ARG1/CA1/SLC35A3/SLC25A5/SNCA/CPT1C/PLEKHA3/SLC1A3/NFKBIE/CYP4F2/TRH/C2CD2L/PLA2G5/SLC10A2/ACE/STXBP1/LRRC8A/ABCA4/CLN8/BDKRB2/APOC1/SLC2A8/NTRK2/P2RX7/SLC26A10/SLCO4A1/SLC25A6/PDPN/CA4/SLC1A1/TNFRSF11A/CEACAM1/IRS2/SLC26A6/SLC7A3/SLC7A9/CA14/SLC10A7/AQP1/CA12/SLC2A6/SLC32A1/SLC16A4/PRKAG2/MFSD2A/IL1B/PLA2G2A/GLTP/STARD5/SLCO2A1/SLC23A1/LRRC8E/NCOA2/SLC26A8/SLC37A4/SLC38A4/TRIAP1/SLC17A5/PLTP/SLCO2B1/UNC13B/GIPC1/NR1H4/FABP3/SLC25A29/SLC6A1/ABAT/NCOA1	75
BP	GO:0051147	regulation of muscle cell differentiation	31/2486	181/18670	0.08303	0.2688	0.2107	RBM4/YY1/BDNF/MAPK11/PRDM6/TMEM119/BHLHE41/TGFB1/CDK9/AKAP13/RBPMS2/CYP26B1/BOC/MIR21/BMP2/EHD2/SIRT1/IGF1/EFNB2/CDON/FRS2/MORF4L2/NOTCH1/SHOX2/MSX1/TBX1/MTOR/SOX6/NFATC3/PIN1/OLFM2	31
BP	GO:0006705	mineralocorticoid biosynthetic process	4/2486	13/18670	0.08335	0.2688	0.2107	BMP2/CYP21A2/REST/DKK3	4
BP	GO:0008212	mineralocorticoid metabolic process	4/2486	13/18670	0.08335	0.2688	0.2107	BMP2/CYP21A2/REST/DKK3	4
BP	GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production	4/2486	13/18670	0.08335	0.2688	0.2107	IL23R/IL1B/IL17D/TLR9	4
BP	GO:0035563	positive regulation of chromatin binding	4/2486	13/18670	0.08335	0.2688	0.2107	PARP9/DDX11/DTX3L/EBF2	4
BP	GO:0038065	collagen-activated signaling pathway	4/2486	13/18670	0.08335	0.2688	0.2107	COL4A1/COL4A2/DDR2/ITGA2	4
BP	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein	4/2486	13/18670	0.08335	0.2688	0.2107	SH2B3/PPP2CA/CAV1/INPP5F	4
BP	GO:0043301	negative regulation of leukocyte degranulation	4/2486	13/18670	0.08335	0.2688	0.2107	FCGR2B/CEACAM1/IL13RA2/CD300A	4
BP	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway	4/2486	13/18670	0.08335	0.2688	0.2107	IGF1/IGFBP4/IGFBP5/IGFBP3	4
BP	GO:0045779	negative regulation of bone resorption	4/2486	13/18670	0.08335	0.2688	0.2107	INPP5D/TNFAIP3/TMEM119/P2RX7	4
BP	GO:0050713	negative regulation of interleukin-1 beta secretion	4/2486	13/18670	0.08335	0.2688	0.2107	TNFAIP3/ZC3H12A/PML/NLRP7	4
BP	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain	4/2486	13/18670	0.08335	0.2688	0.2107	CACNB3/CXCL12/KCNA1/ITGA2	4
BP	GO:0051451	myoblast migration	4/2486	13/18670	0.08335	0.2688	0.2107	AKIRIN1/THBS4/SIX1/SMO	4
BP	GO:0061029	eyelid development in camera-type eye	4/2486	13/18670	0.08335	0.2688	0.2107	INHBA/TWIST1/JUN/EGFR	4
BP	GO:0061430	bone trabecula morphogenesis	4/2486	13/18670	0.08335	0.2688	0.2107	FBN2/SEMA4D/THBS3/SFRP1	4
BP	GO:0071696	ectodermal placode development	4/2486	13/18670	0.08335	0.2688	0.2107	NRP1/SIX1/FRS2/TBX2	4
BP	GO:0071872	cellular response to epinephrine stimulus	4/2486	13/18670	0.08335	0.2688	0.2107	SIRT2/SNCA/PDE4B/RYR2	4
BP	GO:0072672	neutrophil extravasation	4/2486	13/18670	0.08335	0.2688	0.2107	CD177/IL1R1/PIK3CD/XG	4
BP	GO:0098903	regulation of membrane repolarization during action potential	4/2486	13/18670	0.08335	0.2688	0.2107	DLG1/CACNB3/FLNA/CAV1	4
BP	GO:0099633	protein localization to postsynaptic specialization membrane	4/2486	13/18670	0.08335	0.2688	0.2107	DLG1/DLG2/GPC4/GPC6	4
BP	GO:0099645	neurotransmitter receptor localization to postsynaptic specialization membrane	4/2486	13/18670	0.08335	0.2688	0.2107	DLG1/DLG2/GPC4/GPC6	4
BP	GO:1902947	regulation of tau-protein kinase activity	4/2486	13/18670	0.08335	0.2688	0.2107	CLU/SORL1/HSP90AA1/HSP90AB1	4
BP	GO:1903651	positive regulation of cytoplasmic transport	4/2486	13/18670	0.08335	0.2688	0.2107	SORL1/DAB2/MSN/MAP2	4
BP	GO:1990403	embryonic brain development	4/2486	13/18670	0.08335	0.2688	0.2107	TRA2B/RPL10/IFT140/TBC1D23	4
BP	GO:0051302	regulation of cell division	29/2486	168/18670	0.08435	0.2719	0.2131	SIRT2/CIT/NCOA3/RAB11FIP4/TGFB2/VEGFC/TGFB1/TAL1/PRDM15/FLCN/THBS4/BCL2L1/SFRP2/PTN/CDK2AP2/PKP4/PLK3/YBX1/PLK1/KIF20A/IL1B/UVRAG/PKN2/INTU/E2F8/GIPC1/SETD2/KIF14/PIN1	29
BP	GO:0001656	metanephros development	17/2486	90/18670	0.08447	0.2722	0.2133	IRX2/NIPBL/SPRY1/HES1/IRX3/WWTR1/SIX1/PDGFRA/SMO/PDGFRB/SOX9/CD34/YAP1/GLI3/HOXA11/SIX2/FBN1	17
BP	GO:0051148	negative regulation of muscle cell differentiation	13/2486	65/18670	0.08484	0.2725	0.2136	YY1/BDNF/PRDM6/TMEM119/BHLHE41/RBPMS2/MIR21/BMP2/FRS2/NOTCH1/MSX1/SOX6/NFATC3	13
BP	GO:0051187	cofactor catabolic process	13/2486	65/18670	0.08484	0.2725	0.2136	HBB/HBD/SNCA/CYP4F2/PRDX2/GGT5/PXDN/HBM/VCP/HP/CBR3/HBQ1/ALDH1L2	13
BP	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic	8/2486	35/18670	0.08502	0.2725	0.2136	LSM4/CNOT8/LSM7/DCP2/EXOSC3/POLR2G/CNOT7/DDX6	8
BP	GO:0001893	maternal placenta development	8/2486	35/18670	0.08502	0.2725	0.2136	GHRL/STOX2/SPP1/STC1/PTN/NR2F2/STC2/JUNB	8
BP	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	8/2486	35/18670	0.08502	0.2725	0.2136	UBXN1/SMARCC1/USP7/WAC/MTM1/CAMLG/HSP90AB1/GIPC1	8
BP	GO:0032689	negative regulation of interferon-gamma production	8/2486	35/18670	0.08502	0.2725	0.2136	INHBA/PGLYRP1/GAS6/ZC3H12A/PDCD1LG2/IL33/NR1H4/AXL	8
BP	GO:0032735	positive regulation of interleukin-12 production	8/2486	35/18670	0.08502	0.2725	0.2136	IRF8/MAPK11/IRF1/TRAF6/IL23R/RELA/PLCB1/TLR9	8
BP	GO:0051954	positive regulation of amine transport	8/2486	35/18670	0.08502	0.2725	0.2136	PINK1/TRH/STXBP1/P2RX7/CXCL12/OXTR/SLC6A1/ABAT	8
BP	GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway	8/2486	35/18670	0.08502	0.2725	0.2136	TNFAIP3/NFKBIA/UBA52/ITCH/TRAF6/CYLD/RELA/UBC	8
BP	GO:1903539	protein localization to postsynaptic membrane	8/2486	35/18670	0.08502	0.2725	0.2136	GRIP1/DLG1/DLG2/GRIP2/GPC4/GPC6/GRASP/RAB8A	8
BP	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	36/2486	215/18670	0.0856	0.2743	0.215	PMAIP1/CRADD/FADD/PPARG/CASP4/RPS27L/SNCA/TNF/BCL10/NOL3/HERPUD1/GAS6/RAF1/SIRT1/SFRP2/PML/MAP3K5/VCP/PRR7/MMP9/WNT9A/AQP1/KLF4/SERPINB9/IFI6/DIABLO/NLRP1/REST/PPM1F/DLC1/TRIAP1/BAK1/PDCD5/ANP32B/MGMT/CRYAB	36
BP	GO:0048259	regulation of receptor-mediated endocytosis	19/2486	103/18670	0.08609	0.2753	0.2158	CLU/ITGB3/NTF3/ARF1/ANKRD13D/UNC119/ANKRD13B/APOC1/DAB2/ANKRD13A/EGF/HNRNPK/CBL/SFRP4/EFNB2/CCL21/MAGI2/ARC/SYT11	19
BP	GO:0001885	endothelial cell development	12/2486	59/18670	0.0861	0.2753	0.2158	CLDN5/MYADM/PROC/TNF/PDE2A/RAPGEF3/COL18A1/STC1/MSN/IL1B/TJP1/CDH5	12
BP	GO:0032890	regulation of organic acid transport	12/2486	59/18670	0.0861	0.2753	0.2158	ARG1/SNCA/CYP4F2/TRH/STXBP1/P2RX7/TNFRSF11A/IRS2/IL1B/FABP3/SLC6A1/ABAT	12
BP	GO:0045843	negative regulation of striated muscle tissue development	12/2486	59/18670	0.0861	0.2753	0.2158	SIRT2/YY1/MAPK11/TBX5/TWIST1/AKIRIN1/TGFB1/BMP2/MIR17HG/FRS2/JARID2/SOX6	12
BP	GO:0002478	antigen processing and presentation of exogenous peptide antigen	30/2486	175/18670	0.08616	0.2753	0.2158	PSMD14/PSMD12/ITGB5/HLA-DPB1/KIF26A/ARF1/DYNC1I1/PSMD7/PDIA3/PSMB5/ACTR10/FCGR2B/TRAF6/KIF4A/AP2A2/HLA-B/SEC24B/PSMB7/KIF2C/CAPZA1/SNAP23/PSMD1/PSMD9/CTSF/DYNLL2/PSME1/AP1S3/DCTN4/HLA-A/KLC1	30
BP	GO:0021575	hindbrain morphogenesis	9/2486	41/18670	0.08672	0.2767	0.2168	FAIM2/HERC1/LDB1/HES1/AGTPBP1/SMO/DLC1/HSPA5/KIF14	9
BP	GO:0044091	membrane biogenesis	9/2486	41/18670	0.08672	0.2767	0.2168	TLCD2/STX2/CLIP3/CAV2/EMP2/MAGI2/CAV1/NLGN4X/EPHB2	9
BP	GO:0050798	activated T cell proliferation	9/2486	41/18670	0.08672	0.2767	0.2168	FADD/ARG1/IGFBP2/MIR21/IL23R/IGF1/PDCD1LG2/IL2/RC3H1	9
BP	GO:0071482	cellular response to light stimulus	23/2486	129/18670	0.0868	0.2767	0.2168	C9orf116/GUCY2D/MME/YY1/EP300/EIF2AK4/EIF2S1/PPID/CREBBP/USP28/NFATC4/SIRT1/PTN/BMF/AQP1/PPEF1/TRIAP1/BAK1/METAP1/PDE6G/TAF1/MFAP4/HYAL1	23
BP	GO:0032715	negative regulation of interleukin-6 production	11/2486	53/18670	0.08696	0.2767	0.2168	ORM1/INPP5D/TNFAIP3/TNF/GHRL/GAS6/CX3CL1/ZC3H12A/TLR9/NR1H4/SYT11	11
BP	GO:0035065	regulation of histone acetylation	11/2486	53/18670	0.08696	0.2767	0.2168	MUC1/SNCA/TWIST1/TGFB1/FLCN/SIRT1/SETD5/IL1B/SET/RPS6KA5/SIN3A	11
BP	GO:0038066	p38MAPK cascade	11/2486	53/18670	0.08696	0.2767	0.2168	DLG1/DUSP10/ZFP36/ZC3H12A/BMP2/CYLD/MAP3K5/IL1B/DUSP1/MAP3K3/PER1	11
BP	GO:0050702	interleukin-1 beta secretion	11/2486	53/18670	0.08696	0.2767	0.2168	ORM1/TNFAIP3/ARG2/LPL/ZC3H12A/P2RX7/PML/FZD5/NLRP1/WNT5A/NLRP7	11
BP	GO:0006953	acute-phase response	10/2486	47/18670	0.08725	0.2767	0.2168	ORM1/EDNRB/TNF/FN1/F8/HP/ASS1/TNFRSF11A/SERPINA3/IL1B	10
BP	GO:0008206	bile acid metabolic process	10/2486	47/18670	0.08725	0.2767	0.2168	OSBP/OSBPL6/HSD3B7/CH25H/SIRT1/OSBPL9/AKR1D1/CYP39A1/NR1H4/NR5A2	10
BP	GO:0021695	cerebellar cortex development	10/2486	47/18670	0.08725	0.2767	0.2168	FAIM2/HERC1/B4GALT2/LDB1/AGTPBP1/TTBK2/SMO/MYH10/HSPA5/KIF14	10
BP	GO:0043303	mast cell degranulation	10/2486	47/18670	0.08725	0.2767	0.2168	PDPK1/STXBP1/BTK/C12orf4/CBL/PIK3CD/IL13RA2/SNAP23/CD300A/LYN	10
BP	GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	10/2486	47/18670	0.08725	0.2767	0.2168	SMAD7/CD83/MIR21/ZC3H12A/IRF4/NFKBIZ/HLX/IL23R/IL2/RC3H1	10
BP	GO:1900744	regulation of p38MAPK cascade	10/2486	47/18670	0.08725	0.2767	0.2168	DLG1/DUSP10/ZC3H12A/BMP2/CYLD/MAP3K5/IL1B/DUSP1/MAP3K3/PER1	10
BP	GO:2001239	regulation of extrinsic apoptotic signaling pathway in absence of ligand	10/2486	47/18670	0.08725	0.2767	0.2168	INHBA/GATA1/TNF/STRADB/PRDX2/CX3CL1/BCL2L1/MCL1/IFI6/IL1B	10
BP	GO:0050870	positive regulation of T cell activation	34/2486	202/18670	0.08755	0.2775	0.2175	FAM49B/PDPK1/HLA-DPB1/FADD/DUSP10/BCL10/TGFB1/IGFBP2/CD276/HES1/CD83/MIR21/NFKBIZ/HLX/TRAF6/IL23R/CYLD/VAV1/IGF1/PDCD1LG2/IL12A/EFNB2/IL2/TNFRSF14/GLI3/IL1B/CCL21/THY1/PAK3/CAV1/LYN/PTPRC/CORO1A/DOCK8	34
BP	GO:0009267	cellular response to starvation	26/2486	149/18670	0.08865	0.2807	0.22	RRAGA/PMAIP1/GABARAPL2/MAP1LC3A/DEPDC5/EIF2AK4/JUN/PPM1D/IFI16/GAS6/EIF2S1/STK24/ZC3H12A/SIRT1/SESN2/MAX/TBL2/MAP3K5/CADPS2/KLF10/SESN3/SFRP1/USP33/MTOR/HSPA5/PDK4	26
BP	GO:2001056	positive regulation of cysteine-type endopeptidase activity	26/2486	149/18670	0.08865	0.2807	0.22	PMAIP1/CRADD/FADD/PPARG/TBC1D10A/CASP4/RPS27L/SNCA/TNF/BCL10/IFI16/SIRT1/ASPH/PML/MAP3K5/VCP/PRR7/DIABLO/NLRP1/REST/PPM1F/DLC1/BAK1/PDCD5/ANP32B/CIDEB	26
BP	GO:0010596	negative regulation of endothelial cell migration	18/2486	97/18670	0.08882	0.281	0.2202	PPARG/TGFB1/MIR21/MMRN2/JUP/STC1/ADAMTS9/CARD10/VASH1/NR2F2/DNAJA4/MEOX2/KLF4/NOTCH1/ANGPT2/PDCD10/DCN/SLIT2	18
BP	GO:1902882	regulation of response to oxidative stress	18/2486	97/18670	0.08882	0.281	0.2202	TNF/NOL3/SFPQ/PINK1/FBXW7/MIR21/PYCR1/SIRT1/SESN2/GCH1/NME5/HSPB1/MMP3/SESN3/MCL1/REST/NONO/MAPKAP1	18
BP	GO:0045619	regulation of lymphocyte differentiation	29/2486	169/18670	0.08943	0.2819	0.221	INPP5D/INHBA/PPP2R3C/PGLYRP1/IRF1/SMAD7/DUSP10/TGFB1/PRDX2/GAS6/CYP26B1/CD83/MIR21/ZC3H12A/IRF4/NFKBIZ/HLX/BTK/IL23R/CYLD/MIR17HG/IL12A/IL2/GLI3/SFRP1/TLR9/RC3H1/PTPRC/AXL	29
BP	GO:0031579	membrane raft organization	6/2486	24/18670	0.08977	0.2819	0.221	MYADM/CAV2/DLG1/EMP2/CAV1/PTPRC	6
BP	GO:0034162	toll-like receptor 9 signaling pathway	6/2486	24/18670	0.08977	0.2819	0.221	LILRA4/TRAF6/RAB7B/TLR9/NR1H4/RSAD2	6
BP	GO:0034505	tooth mineralization	6/2486	24/18670	0.08977	0.2819	0.221	FAM20A/CNNM4/BCOR/ALPL/ASPN/TBX1	6
BP	GO:0036010	protein localization to endosome	6/2486	24/18670	0.08977	0.2819	0.221	SORL1/NRP1/ANKRD13A/MSN/EGF/DTX3L	6
BP	GO:0042104	positive regulation of activated T cell proliferation	6/2486	24/18670	0.08977	0.2819	0.221	FADD/IGFBP2/MIR21/IL23R/IGF1/IL2	6
BP	GO:0046639	negative regulation of alpha-beta T cell differentiation	6/2486	24/18670	0.08977	0.2819	0.221	SMAD7/ZC3H12A/HLX/IL2/GLI3/RC3H1	6
BP	GO:0046697	decidualization	6/2486	24/18670	0.08977	0.2819	0.221	GHRL/SPP1/STC1/PTN/STC2/JUNB	6
BP	GO:0050687	negative regulation of defense response to virus	6/2486	24/18670	0.08977	0.2819	0.221	HTRA1/ITCH/GPATCH3/TSPAN6/RNF125/PCBP2	6
BP	GO:0062009	secondary palate development	6/2486	24/18670	0.08977	0.2819	0.221	DLG1/TGFB2/JAG2/WNT5A/TBX1/MMP25	6
BP	GO:0071218	cellular response to misfolded protein	6/2486	24/18670	0.08977	0.2819	0.221	SDF2L1/KLHL15/DNAJB14/DERL1/VCP/SDF2	6
BP	GO:0086064	cell communication by electrical coupling involved in cardiac conduction	6/2486	24/18670	0.08977	0.2819	0.221	SRI/ATP1B2/GJA5/FKBP1B/RYR2/CAV1	6
BP	GO:1904376	negative regulation of protein localization to cell periphery	6/2486	24/18670	0.08977	0.2819	0.221	TGFB1/DAB2/BCL2L1/LRRC15/PKDCC/MRAP2	6
BP	GO:2000209	regulation of anoikis	6/2486	24/18670	0.08977	0.2819	0.221	NTRK2/CEACAM6/MCL1/NOTCH1/CAV1/PDK4	6
BP	GO:0032869	cellular response to insulin stimulus	36/2486	216/18670	0.0901	0.2829	0.2217	GRB10/PDPK1/PPARG/SLC25A33/ATP6V1E1/APC/RAB13/PRKCB/CAV2/LPL/SORL1/GRB14/ATP6V0A2/SMARCC1/ATP6V1G3/IGF1R/SIRT1/SLC2A8/RARRES2/RELA/CEACAM1/IRS2/SESN3/IDE/BCAR1/CPEB1/MYO1C/IL1B/SORBS1/WDTC1/CAPN10/RAB8A/KL/PDK4/NR1H4/CPEB2	36
BP	GO:0072593	reactive oxygen species metabolic process	46/2486	284/18670	0.09055	0.2841	0.2227	CLU/HBB/SIRT2/HBD/PMAIP1/DDAH1/MMP8/ARG2/CD177/SLC25A33/SNCA/TNF/TGFB1/PINK1/PRDX2/PXDN/HBM/HSP90AA1/MIR21/ZC3H12A/SESN2/GCH1/EGFR/NOS3/VAV1/P2RX7/HP/ASS1/MMP3/AGTR1/KLF4/PDGFRB/CD34/IFI6/ACP5/HBQ1/IL1B/CPS1/NOX4/HSP90AB1/CAV1/MTOR/SOD3/PDK4/CRYAB/NQO1	46
BP	GO:0030856	regulation of epithelial cell differentiation	27/2486	156/18670	0.09082	0.2848	0.2232	NCOA3/CLDN5/KEAP1/PROC/TNF/CD109/HOXA7/ZFP36/HES1/CDKN1C/CCND1/MIR21/FOXC1/WWTR1/KIAA1109/CEACAM1/MMP9/SFRP4/SMO/SOX9/NOTCH1/YAP1/IL1B/APOLD1/CDH5/CAV1/FOXJ2	27
BP	GO:0071826	ribonucleoprotein complex subunit organization	47/2486	291/18670	0.0912	0.2857	0.2239	RPS27/RPS28/CPSF7/EIF5/LSM4/PELO/RPS27L/EIF3L/EIF4B/YTHDC1/CLNS1A/NOL3/DHX9/RPS15/DENR/SRPK2/EIF2S1/HSP90AA1/G3BP2/MRPL20/RPL10/EIF2A/EIF4H/EIF3F/RSL24D1/GEMIN6/VCP/ATXN2L/SNRPB/CELF1/RPS10/RPL6/NUFIP1/ZFAND1/SF3B1/RBMX/EIF3K/EIF3M/CNOT7/HSP90AB1/STYXL1/POLR2D/RC3H1/KLC1/DDX6/CNOT1/GFM2	47
BP	GO:0042110	T cell activation	72/2486	464/18670	0.0913	0.2857	0.2239	FAM49B/CD1C/PDPK1/HLA-DPB1/ARG2/FADD/ARG1/EIF2AK4/IRF1/SMAD7/DLG1/DUSP10/BCL10/TGFB1/IGFBP2/PRDX2/CD276/HES1/CYP26B1/FCGR2B/CD83/TWSG1/MIR21/JAG2/ZC3H12A/IRF4/NFKBIZ/HLX/PTGER4/SP3/TRAF6/IL23R/CYLD/VAV1/BATF/P2RX7/IGF1/MSN/CDH26/JMJD6/PRR7/CEACAM1/PIK3CD/ITGAL/DDOST/PDCD1LG2/IL12A/EFNB2/TMEM98/IL2/TNFRSF14/GLI3/MYH9/IL1B/FKBP1B/CCL21/THY1/PPP3CB/FZD5/GPNMB/PAK3/CD300A/CAV1/MTOR/LYN/SPN/RC3H1/PTPRC/CORO1A/RSAD2/DOCK8/CD151	72
BP	GO:0032024	positive regulation of insulin secretion	14/2486	72/18670	0.09133	0.2857	0.2239	SRI/GHRL/SERP1/TRH/PFKFB2/C2CD2L/TM7SF3/IRS2/STX4/PPP3CB/PSMD9/CAPN10/NR1H4/ABAT	14
BP	GO:0060193	positive regulation of lipase activity	14/2486	72/18670	0.09133	0.2857	0.2239	NTF3/ARHGAP6/PDPK1/BDNF/FLT1/PLA2G5/P2RY12/EGFR/NTRK2/PLCB2/GPIHBP1/PDGFRA/AGTR1/PDGFRB	14
BP	GO:0061180	mammary gland epithelium development	14/2486	72/18670	0.09133	0.2857	0.2239	LRP5L/IQGAP3/CSF1/TGFB1/PHB2/CCND1/PML/SMO/RREB1/WNT5A/MSX1/MST1/MGMT/LRP5	14
BP	GO:0030098	lymphocyte differentiation	56/2486	353/18670	0.09166	0.2866	0.2246	INPP5D/FADD/ITGA4/INHBA/EP300/PPP2R3C/KLF6/GON4L/PGLYRP1/IRF1/SMAD7/DUSP10/TGFB1/PRDX2/GAS6/CYP26B1/FCGR2B/CD83/MIR21/JAG2/LRRC8A/ZC3H12A/IRF4/ZBTB7A/NFKBIZ/HLX/BTK/PTGER4/SP3/IL23R/CYLD/VAV1/BATF/JMJD6/MFNG/MIR17HG/PRR7/PIK3CD/IL12A/TMEM98/IL2/NOTCH2/GLI3/SFRP1/PPP3CB/FZD5/TLR9/POU2F2/MTOR/BAK1/SPN/RC3H1/PTPRC/DOCK11/RSAD2/AXL	56
BP	GO:0010923	negative regulation of phosphatase activity	19/2486	104/18670	0.09279	0.29	0.2273	SPOCD1/SH2D4A/PPP1R15A/BAG4/TNF/TGFB2/PCDH11X/DLG2/CEP192/CCDC8/SEMA4D/PTN/TMEM225/FARP1/FKBP1B/ELL/PCIF1/SET/STYXL1	19
BP	GO:0034612	response to tumor necrosis factor	50/2486	312/18670	0.09288	0.2901	0.2274	CHI3L1/PSMD14/PSMD12/TNFAIP3/ZFAND6/CASP4/BAG4/CLIP3/SPATA2/NFKBIA/TNF/NOL3/DHX9/PSMD7/PSMB5/LCN2/ZFP36/HIPK1/GAS6/MAP3K14/CX3CL1/SMPD3/ZC3H12A/PLVAP/SIRT1/CCL13/GCH1/CYLD/NPNT/MAP3K5/RELA/ASS1/TNFRSF11A/CCDC3/PSMB7/HAS2/TNFRSF14/PSMD1/CCL21/SFRP1/PSMD9/LIMS1/CCL8/MADD/POSTN/PSME1/ADAMTS12/NR1H4/CCL18/HYAL1	50
BP	GO:0007613	memory	21/2486	117/18670	0.0931	0.2902	0.2275	NTAN1/NTF3/FGF13/BDNF/EIF2AK4/B4GALT2/CUX2/CREB1/YTHDF1/NFATC4/KCNK10/ITGA3/PTN/PLCB1/HRH1/PPP3CB/OXTR/MTOR/RGS14/ARC/SHANK3	21
BP	GO:0010906	regulation of glucose metabolic process	21/2486	117/18670	0.0931	0.2902	0.2275	PMAIP1/GNMT/EP300/PFKFB2/WDR5/SIRT1/SESN2/IGF1/GNB3/IGFBP4/IRS2/C1QTNF1/FOXK2/KHK/SORBS1/NCOA2/MTOR/MST1/MIDN/PDK4/IGFBP3	21
BP	GO:0060147	regulation of posttranscriptional gene silencing	21/2486	117/18670	0.0931	0.2902	0.2275	PPARG/NUP93/FXR1/DHX9/TGFB1/ZFP36/ZC3H12A/NUP50/EGFR/POLR2G/NEAT1/NUP153/NUP210/RAE1/NUP188/NUP160/NUP54/NUP214/ZC3H10/NUP155/POLR2D	21
BP	GO:0060966	regulation of gene silencing by RNA	21/2486	117/18670	0.0931	0.2902	0.2275	PPARG/NUP93/FXR1/DHX9/TGFB1/ZFP36/ZC3H12A/NUP50/EGFR/POLR2G/NEAT1/NUP153/NUP210/RAE1/NUP188/NUP160/NUP54/NUP214/ZC3H10/NUP155/POLR2D	21
BP	GO:1901880	negative regulation of protein depolymerization	13/2486	66/18670	0.09339	0.291	0.228	EPS8/FGF13/TMOD1/NAV3/APC/CLASP2/AVIL/TTBK2/LMOD1/PLEKHH2/MID1/CAPZA1/CLASP1	13
BP	GO:0050772	positive regulation of axonogenesis	16/2486	85/18670	0.09437	0.2939	0.2303	BDNF/TRAK1/PLXNA3/RND2/NRP1/L1CAM/FN1/NTRK2/SEMA4D/SKIL/CXCL12/NIN/SHOX2/PLXNA1/SLIT2/GDI1	16
BP	GO:0072503	cellular divalent inorganic cation homeostasis	76/2486	493/18670	0.09452	0.294	0.2304	SRI/SLC24A3/PDPK1/ITPR1/EDNRB/GTF2I/ATP7B/PRKCB/HSP90B1/SNCA/MCOLN3/NOL3/SPPL3/GHRL/TGFB1/LPAR6/ELANE/HERPUD1/CACNB3/TACR1/DIAPH1/FAM155A/CX3CL1/MT2A/CXCR1/BDKRB2/GPR4/PTGER4/EDN3/DDIT3/CCL13/STC1/P2RX7/LPAR4/MCHR1/GPR35/PML/CXCL12/SLC24A5/PLCB2/SLC25A27/PTH1R/PTGFR/PLCB1/PDGFRA/KCNA5/AGTR1/C1QTNF1/IL2/RAMP3/APLNR/KCNK3/CIB2/IBTK/FKBP1B/CCL21/THY1/ANK2/SYPL2/OXTR/WNT5A/P2RY8/CCL8/RYR2/CDH5/CAV1/STC2/LYN/BAK1/C19orf12/ADCYAP1/SLC30A9/DMD/WFS1/PTPRC/CORO1A	76
BP	GO:0000305	response to oxygen radical	7/2486	30/18670	0.09474	0.294	0.2304	TNF/PRDX2/MIR21/GCH1/NOS3/SOD3/NQO1	7
BP	GO:0006517	protein deglycosylation	7/2486	30/18670	0.09474	0.294	0.2304	EDEM1/AGA/MAN2A2/RNF139/RNF103/MAN2A1/ENGASE	7
BP	GO:0046320	regulation of fatty acid oxidation	7/2486	30/18670	0.09474	0.294	0.2304	PPARG/TWIST1/IRS2/PRKAG2/MTOR/PDK4/FABP3	7
BP	GO:0061082	myeloid leukocyte cytokine production	7/2486	30/18670	0.09474	0.294	0.2304	BCL10/TGFB2/TGFB1/GAS6/DDX21/SIRT1/WNT5A	7
BP	GO:0071480	cellular response to gamma radiation	7/2486	30/18670	0.09474	0.294	0.2304	XRCC6/POLE3/BCL2L1/YAP1/NOX4/HSPA5/CRYAB	7
BP	GO:1905476	negative regulation of protein localization to membrane	7/2486	30/18670	0.09474	0.294	0.2304	TGFB1/DAB2/BCL2L1/LRRC15/PKDCC/MRAP2/GDI1	7
BP	GO:0048635	negative regulation of muscle organ development	12/2486	60/18670	0.09522	0.2953	0.2315	SIRT2/YY1/MAPK11/TBX5/TWIST1/AKIRIN1/TGFB1/BMP2/MIR17HG/FRS2/JARID2/SOX6	12
BP	GO:0046425	regulation of JAK-STAT cascade	24/2486	137/18670	0.09541	0.2956	0.2317	SH2B3/TNF/PPP2CA/HES1/CRLF1/PARP9/IL23R/IGF1/EGF/IL12A/IL2/NOTCH1/CRLF3/CDK5R1/IL26/CD300A/CNOT7/CAV1/HCLS1/INPP5F/IL10RA/LYN/GHR/PTPRC	24
BP	GO:0072655	establishment of protein localization to mitochondrion	24/2486	137/18670	0.09541	0.2956	0.2317	ABLIM3/PMAIP1/TIMM23/DNLZ/TOMM20/BAG4/MFF/DNAJA1/TIMM44/PINK1/TIMM10/MOAP1/ARIH2/FBXW7/HSP90AA1/DDIT3/SLC25A6/GRPEL1/YWHAZ/BMF/FZD5/UBE2D3/TP53BP2/PDCD5	24
BP	GO:0010948	negative regulation of cell cycle process	57/2486	361/18670	0.09562	0.2961	0.2321	MUC1/RBM14/PSMD14/PSMD12/CRADD/MSH6/CNOT8/CNOT4/EP300/RPS27L/SYF2/APC/PSMD7/CDK9/PSMB5/MTBP/KANK2/FBXW7/CCND1/CTDSPL/CDKN2C/MIR21/MDM4/MAX/MDM1/YAF2/PML/FOXN3/BUB1B/CDK2AP2/PHC3/PLK3/PSMB7/KLF4/PLK1/PSMD1/BTG2/CDKN2B/PSMD9/GPNMB/FAM107A/DUSP1/CNOT7/HSP90AB1/PCGF2/TTK/TRIAP1/TNKS1BP1/TMEM67/E2F8/PSME1/EPC1/ZNF268/NEK2/CNOT1/CUL1/ZNF830	57
BP	GO:0009749	response to glucose	33/2486	197/18670	0.09583	0.2966	0.2325	SRI/LRP5L/TRA2B/CDK16/LPL/GHRL/TGFB1/TRH/PFKFB2/RAB11FIP5/C2CD2L/GAS6/ERN1/ADRA2A/RAF1/IGF1R/SESN2/JAGN1/GJB6/IRS2/KHK/POLG/STX4/FKBP1B/ANGPT2/PPP3CB/NOX4/COL6A2/UNC13B/NR1H4/LRP5/SIN3A/EIF2B2	33
BP	GO:0016197	endosomal transport	37/2486	224/18670	0.09588	0.2966	0.2325	TRAPPC10/VPS53/GRIP1/TBC1D10A/TMEM87A/RAB13/RAB11FIP4/LYST/SQSTM1/STX16/SORL1/UBA52/PLEKHJ1/VPS37A/GRIP2/CHMP6/EHD2/CHMP1B/VCP/VPS37B/DENND2A/GRASP/RAB7B/LAPTM4B/TINAGL1/DCLK1/GOSR1/RAB6B/UBC/TBC1D23/VPS26B/ACAP2/HEATR5B/INPP5F/RAB8A/CCDC93/MAGEL2	37
BP	GO:0022037	metencephalon development	20/2486	111/18670	0.09641	0.2976	0.2333	FAIM2/HERC1/B4GALT2/CRKL/LDB1/FCGR2B/FOXC1/PTN/AGTPBP1/TTBK2/SEC24B/SMO/CDK5R1/NLGN4X/MYH10/FZD4/HSPA5/KIF14/ABAT/NCOA1	20
BP	GO:0031623	receptor internalization	20/2486	111/18670	0.09641	0.2976	0.2333	ITGB3/NTF3/ARF1/CD9/SNCA/ANKRD13D/ANKRD13B/CXCR1/CALCRL/ANKRD13A/EGF/RAMP2/CEACAM1/SFRP4/EFNB2/RAMP3/DNM1/MAGI2/CAV1/ARC	20
BP	GO:0007416	synapse assembly	30/2486	177/18670	0.09644	0.2976	0.2333	NRCAM/BDNF/SNCA/GHRL/CRKL/CUX2/AGRN/GPC4/TPBG/NTRK2/LRRN1/SEMA4D/SIX1/FLRT2/SDK1/SRPX2/PCDHB14/EFNB2/POU4F1/FARP1/GAP43/PCDH17/FZD5/OXTR/WNT5A/MAGI2/NLGN4X/SLIT1/EPHB2/SHANK3	30
BP	GO:0032663	regulation of interleukin-2 production	11/2486	54/18670	0.0967	0.2976	0.2333	TNFAIP3/NAV3/ZFP36/CD83/IRF4/PDE4B/TRAF6/CD34/IL1B/PTPRC/NR1H4	11
BP	GO:0050994	regulation of lipid catabolic process	11/2486	54/18670	0.0967	0.2976	0.2333	TNF/TWIST1/SCT/SORL1/ADRA2A/APOC1/RARRES2/IRS2/BSCL2/IL1B/MTOR	11
BP	GO:0070206	protein trimerization	11/2486	54/18670	0.0967	0.2976	0.2333	ARG1/COL6A1/TRIM6/LCN2/TRIM21/HSF4/NUP54/C1QTNF1/COL6A2/ATXN10/COL1A2	11
BP	GO:0034314	Arp2/3 complex-mediated actin nucleation	8/2486	36/18670	0.09717	0.2976	0.2333	ARF1/AP1AR/WHAMM/WASF1/FCHSD2/NCKAP1/ARPC2/MAGEL2	8
BP	GO:0035872	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	8/2486	36/18670	0.09717	0.2976	0.2333	TNFAIP3/NFKBIA/UBA52/ITCH/TRAF6/CYLD/RELA/UBC	8
BP	GO:0071634	regulation of transforming growth factor beta production	8/2486	36/18670	0.09717	0.2976	0.2333	LTBP1/TGFB2/CREB1/CX3CL1/CD34/LAPTM4B/ITGB8/HSP90AB1	8
BP	GO:0071709	membrane assembly	8/2486	36/18670	0.09717	0.2976	0.2333	TLCD2/STX2/CAV2/EMP2/MAGI2/CAV1/NLGN4X/EPHB2	8
BP	GO:1902905	positive regulation of supramolecular fiber organization	34/2486	204/18670	0.09717	0.2976	0.2333	CLU/RHOBTB1/CTTN/BAG4/NAV3/ARF1/DLG1/TPM1/NRP1/CX3CL1/RAPGEF3/AP1AR/NIN/LMOD1/WHAMM/WASF1/MYO1C/FCHSD2/CCL21/SFRP1/CDK5R1/NCKAP1/NOX4/PPM1F/FLNA/ARPC2/MTOR/CLASP1/PFN1/CDC42EP5/CORO1A/ARHGEF15/LIMCH1/MAGEL2	34
BP	GO:0010256	endomembrane system organization	68/2486	438/18670	0.09752	0.2976	0.2333	CLU/COG3/GOLGA5/TLCD2/CIT/SYTL4/MPP5/SLC4A1/STX2/AKAP8L/LYST/PRKCB/SNX19/SQSTM1/TMEM170A/CAV2/ARFGEF2/PPP2CA/TGFB2/NUP93/STX16/SERP1/CREB1/ATL2/PACSIN1/PLEKHJ1/CLASP2/FBXW8/VPS37A/RAB3GAP2/CHMP6/EHD2/CHMP1B/ARHGEF7/JAGN1/FNBP1L/P2RX7/SEC16A/OBSL1/MTSS1/PLSCR4/YWHAZ/CSNK1A1/VPS37B/UBL4A/LMAN1L/WHAMM/PLK3/DNM1/NUP155/PLK1/COL5A1/LAPTM4B/MYH9/ANK2/SYPL2/PDCD10/SH3TC2/FCHO1/CAV1/CLASP1/BNIP1/MYH10/TMEM43/FHDC1/PTPRC/SUN2/SYT11	68
BP	GO:0001774	microglial cell activation	10/2486	48/18670	0.0977	0.2976	0.2333	CLU/C1QA/MMP8/SNCA/TNF/JUN/CX3CL1/IL33/TREM2/PTPRC	10
BP	GO:0002269	leukocyte activation involved in inflammatory response	10/2486	48/18670	0.0977	0.2976	0.2333	CLU/C1QA/MMP8/SNCA/TNF/JUN/CX3CL1/IL33/TREM2/PTPRC	10
BP	GO:0002279	mast cell activation involved in immune response	10/2486	48/18670	0.0977	0.2976	0.2333	PDPK1/STXBP1/BTK/C12orf4/CBL/PIK3CD/IL13RA2/SNAP23/CD300A/LYN	10
BP	GO:0002762	negative regulation of myeloid leukocyte differentiation	10/2486	48/18670	0.0977	0.2976	0.2333	C1QC/INPP5D/INHBA/HOXA7/LTF/FBXW7/CEACAM1/SFRP1/LYN/FBN1	10
BP	GO:0030850	prostate gland development	10/2486	48/18670	0.0977	0.2976	0.2333	FKBP4/SMARCC1/SULF1/FRS2/SOX9/NOTCH1/GLI3/SFRP1/WNT5A/TNC	10
BP	GO:0046850	regulation of bone remodeling	10/2486	48/18670	0.0977	0.2976	0.2333	ITGB3/INPP5D/TNFAIP3/TMEM119/SPP1/EGFR/P2RX7/TNFRSF11A/SFRP1/PDK4	10
BP	GO:0055010	ventricular cardiac muscle tissue morphogenesis	10/2486	48/18670	0.0977	0.2976	0.2333	SMAD7/TGFB2/TGFB1/TPM1/FOXC1/UBE4B/POU4F1/NOTCH1/ZFPM2/RYR2	10
BP	GO:0072604	interleukin-6 secretion	10/2486	48/18670	0.0977	0.2976	0.2333	MBP/TNF/TWIST1/LPL/DHX9/GAS6/ZC3H12A/IFIH1/IL1B/SYT11	10
BP	GO:0000028	ribosomal small subunit assembly	5/2486	19/18670	0.09795	0.2976	0.2333	RPS27/RPS28/RPS27L/RPS15/RPS10	5
BP	GO:0001710	mesodermal cell fate commitment	5/2486	19/18670	0.09795	0.2976	0.2333	SMAD1/SFRP2/KLF4/HOXA11/SIX2	5
BP	GO:0002076	osteoblast development	5/2486	19/18670	0.09795	0.2976	0.2333	LRP5L/JUND/SATB2/PTH1R/LRP5	5
BP	GO:0002363	alpha-beta T cell lineage commitment	5/2486	19/18670	0.09795	0.2976	0.2333	IRF4/IL23R/BATF/MTOR/SPN	5
BP	GO:0002566	somatic diversification of immune receptors via somatic mutation	5/2486	19/18670	0.09795	0.2976	0.2333	MSH6/POLB/SAMHD1/EXO1/MCM3AP	5
BP	GO:0002726	positive regulation of T cell cytokine production	5/2486	19/18670	0.09795	0.2976	0.2333	IL1R1/TRAF6/IL1B/FZD5/RSAD2	5
BP	GO:0016082	synaptic vesicle priming	5/2486	19/18670	0.09795	0.2976	0.2333	SNCA/STXBP1/CADPS2/SNAP23/UNC13B	5
BP	GO:0030150	protein import into mitochondrial matrix	5/2486	19/18670	0.09795	0.2976	0.2333	TIMM23/DNLZ/TOMM20/TIMM44/GRPEL1	5
BP	GO:0034063	stress granule assembly	5/2486	19/18670	0.09795	0.2976	0.2333	EIF2S1/G3BP2/ATXN2L/STYXL1/DDX6	5
BP	GO:0045414	regulation of interleukin-8 biosynthetic process	5/2486	19/18670	0.09795	0.2976	0.2333	TNF/BCL10/ELANE/KLF4/TLR9	5
BP	GO:0060149	negative regulation of posttranscriptional gene silencing	5/2486	19/18670	0.09795	0.2976	0.2333	PPARG/TGFB1/ZC3H12A/NEAT1/ZC3H10	5
BP	GO:0060219	camera-type eye photoreceptor cell differentiation	5/2486	19/18670	0.09795	0.2976	0.2333	THRB/PTN/ROM1/SOX9/THY1	5
BP	GO:0060967	negative regulation of gene silencing by RNA	5/2486	19/18670	0.09795	0.2976	0.2333	PPARG/TGFB1/ZC3H12A/NEAT1/ZC3H10	5
BP	GO:0072576	liver morphogenesis	5/2486	19/18670	0.09795	0.2976	0.2333	TNFAIP3/LIMS2/FBXW7/PTN/CEACAM1	5
BP	GO:1902644	tertiary alcohol metabolic process	5/2486	19/18670	0.09795	0.2976	0.2333	CYP11A1/BMP2/AKR1C2/REST/DKK3	5
BP	GO:0031641	regulation of myelination	9/2486	42/18670	0.09797	0.2976	0.2333	SIRT2/WASF3/PARD3/DLG1/PTN/LGI4/TMEM98/MTOR/KIF14	9
BP	GO:0051154	negative regulation of striated muscle cell differentiation	9/2486	42/18670	0.09797	0.2976	0.2333	YY1/BDNF/TMEM119/BHLHE41/BMP2/FRS2/NOTCH1/MSX1/SOX6	9
BP	GO:0048639	positive regulation of developmental growth	31/2486	184/18670	0.09805	0.2977	0.2334	BDNF/CSF1/NIPBL/TBX5/CACNA2D2/GHRL/AGRN/RND2/SERP1/CREB1/NRP1/L1CAM/FN1/HLX/SEMA4D/IGF1/CXCL12/ITSN2/PLCB1/MIR17HG/FOXS1/SMO/MTM1/TBX2/NOTCH1/YAP1/ZFPM2/MTOR/GHR/PIN1/GDI1	31
BP	GO:0055076	transition metal ion homeostasis	23/2486	131/18670	0.099	0.3005	0.2355	ALAS2/SRI/EPB42/ARF1/ATP7B/LTF/FXN/IREB2/LCN2/ABCB6/ABCG2/ATP6V0A2/MT2A/COX19/ABCB7/STEAP1/STEAP2/TMEM199/CP/SLC25A37/SLC30A9/HEPH/CUL1	23
BP	GO:0042471	ear morphogenesis	21/2486	118/18670	0.09971	0.3025	0.2371	SPRY2/SLC9A3R1/NIPBL/TWIST1/FOXI1/WDR19/SOBP/SIX1/GJB6/SEC24B/PRRX1/SOX9/ALDH1A3/CTHRC1/WNT5A/MSX1/LRIG3/TBX1/SIX2/EPHB2/MYO15A	21
BP	GO:0002312	B cell activation involved in immune response	14/2486	73/18670	0.09984	0.3027	0.2373	MSH6/PARP3/TGFB1/FCGR2B/EXO1/EXOSC3/BATF/MFNG/IL2/GAPT/NOTCH2/PTPRC/DOCK11/RNF8	14
BP	GO:0009206	purine ribonucleoside triphosphate biosynthetic process	29/2486	171/18670	0.1002	0.3036	0.238	SLC4A1/NUP93/TGFB1/PINK1/PFKFB2/LDHC/DHTKD1/FLCN/ZBTB7A/NUP50/NME5/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/VCP/RAE1/NUP188/NUP160/NUP54/NUP214/NUP155/FOXK2/NUPR1/SLC2A6/PRKAG2/TREM2/PFKP	29
BP	GO:0050863	regulation of T cell activation	50/2486	314/18670	0.1008	0.3055	0.2394	FAM49B/PDPK1/HLA-DPB1/ARG2/FADD/ARG1/IRF1/SMAD7/DLG1/DUSP10/BCL10/TGFB1/IGFBP2/PRDX2/CD276/HES1/CYP26B1/FCGR2B/CD83/TWSG1/MIR21/ZC3H12A/IRF4/NFKBIZ/HLX/TRAF6/IL23R/CYLD/VAV1/IGF1/CEACAM1/PDCD1LG2/IL12A/EFNB2/IL2/TNFRSF14/GLI3/IL1B/CCL21/THY1/GPNMB/PAK3/CD300A/CAV1/LYN/SPN/RC3H1/PTPRC/CORO1A/DOCK8	50
BP	GO:0044839	cell cycle G2/M phase transition	43/2486	266/18670	0.1012	0.3063	0.2401	PSMD14/PSMD12/CIT/SYF2/AKAP8L/PBX1/PSMD7/PSMB5/PPM1D/CCND1/HSP90AA1/CEP192/MIR21/TPX2/TPD52L1/CEP135/FOXN3/HAUS8/PLCB1/ODF2/CCNY/MELK/PLK3/PSMB7/PLK1/PSMD1/KHDRBS1/CDKN2B/PSMD9/NES/SKP2/HAUS2/NDE1/AKAP8/SSNA1/CLASP1/PSME1/PRKAR2B/SIN3A/KIF14/NEK2/CUL1/ZNF830	43
BP	GO:0009135	purine nucleoside diphosphate metabolic process	24/2486	138/18670	0.1016	0.3073	0.2408	SLC4A1/DLG1/NUP93/PFKFB2/DHTKD1/DLG2/ZBTB7A/NUP50/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/RAE1/NUP188/NUP160/NUP54/NUP214/NUP155/FOXK2/NUPR1/SLC2A6/PRKAG2/PFKP	24
BP	GO:0009179	purine ribonucleoside diphosphate metabolic process	24/2486	138/18670	0.1016	0.3073	0.2408	SLC4A1/DLG1/NUP93/PFKFB2/DHTKD1/DLG2/ZBTB7A/NUP50/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/RAE1/NUP188/NUP160/NUP54/NUP214/NUP155/FOXK2/NUPR1/SLC2A6/PRKAG2/PFKP	24
BP	GO:0016485	protein processing	52/2486	328/18670	0.1017	0.3073	0.2409	CLU/PROS1/C1QB/C1QA/C1QC/ADAMTS2/MME/CR1L/CFH/CTSG/FADD/TBC1D10A/FXN/NOL3/SPPL3/CD59/GAS1/C2/IFI16/CFB/ACE/PCSK6/FKRP/SERPING1/ASPH/P2RX7/CFHR2/CPE/CPN1/C1RL/SPCS1/PLAT/TMEM98/C1R/CPXM1/GLI3/MYH9/IL1B/C2CD3/SPCS3/RNF139/C1S/BAK1/CFI/ENPEP/A2M/SPON1/ASPRV1/CLEC3B/CCBE1/NLRP7/CIDEB	52
BP	GO:0007260	tyrosine phosphorylation of STAT protein	16/2486	86/18670	0.1023	0.3088	0.2421	SH2B3/TNF/PPP2CA/HES1/CRLF1/PARP9/IL23R/IGF1/IL12A/IL2/CNOT7/CAV1/HCLS1/INPP5F/LYN/GHR	16
BP	GO:0042058	regulation of epidermal growth factor receptor signaling pathway	16/2486	86/18670	0.1023	0.3088	0.2421	SPRY2/SPRY1/FBXW7/ADRA2A/MIR21/CHMP6/ARHGEF7/EGFR/RHBDF1/EGF/CBL/CEACAM1/MMP9/AFAP1L2/IFI6/PDE6G	16
BP	GO:0060291	long-term synaptic potentiation	16/2486	86/18670	0.1023	0.3088	0.2421	MME/EIF2AK4/SNCA/SQSTM1/CREB1/YTHDF1/NFATC4/NTRK2/PTN/STX4/FAM107A/RGS14/ARC/STAU1/EPHB2/SHANK3	16
BP	GO:0042274	ribosomal small subunit biogenesis	13/2486	67/18670	0.1024	0.3091	0.2423	RPS27/RPS28/RPS27L/NGDN/RPS15/RIOK1/NOM1/DDX52/EMG1/RPS8/RPS10/BYSL/RPS7	13
BP	GO:1990748	cellular detoxification	20/2486	112/18670	0.1034	0.3118	0.2444	HBB/HBD/TNF/PRDX2/CYGB/PXDN/NXN/ABCG2/HBM/MIR21/SESN2/LOXHD1/GCH1/GSTT1/NOS3/HP/GPX8/HBQ1/SOD3/NQO1	20
BP	GO:0046328	regulation of JNK cascade	31/2486	185/18670	0.1034	0.3118	0.2444	MMP8/TNF/DUSP10/DNAJA1/PINK1/TRAF4/ITCH/PPEF2/FCGR2B/ERN1/IGF1R/TRAF6/MAP3K2/EGFR/CYLD/SFRP2/SAMD5/MAP3K5/TPD52L1/PLCB1/TNFRSF11A/FZD10/IL1B/CCL21/SFRP1/FZD5/WNT5A/TLR9/FZD4/PER1/RASSF2	31
BP	GO:0006865	amino acid transport	25/2486	145/18670	0.104	0.312	0.2445	SLC15A4/SLC6A8/ARG1/SNCA/SLC1A3/NFKBIE/TRH/STXBP1/LRRC8A/CLN8/NTRK2/P2RX7/PDPN/SLC1A1/SLC7A3/SLC7A9/SLC32A1/LRRC8E/SLC38A4/SLC17A5/UNC13B/GIPC1/SLC25A29/SLC6A1/ABAT	25
BP	GO:0072511	divalent inorganic cation transport	75/2486	489/18670	0.1042	0.312	0.2445	CNNM4/SRI/SLC24A3/PDPK1/CAMK2G/ITPR1/ATP7B/PRKCB/CACNA2D2/SNCA/MCOLN3/NOL3/TGFB1/PKD2L2/PHB2/FGF14/PDE2A/CACNB3/GAS6/ADRA2A/DIAPH1/FAM155A/CX3CL1/MIR21/P2RY12/MMGT1/PDE4B/GJA4/DDIT3/CALCRL/STAC/NOS3/STC1/P2RX7/MCHR1/GPR35/PML/CXCL12/CATSPER3/SLC24A5/PLCB2/EGF/STAC2/RAMP2/PLCB1/SLC30A6/CACNA2D3/AHNAK/RAMP3/APLNR/PDGFRB/TMEM37/NIPAL2/IBTK/FKBP1B/CCL21/THY1/ANK2/TRPM5/TLR9/SPG7/CCL8/RYR2/PKD1L2/CAV1/STC2/LYN/BAK1/SLC30A9/DMD/WFS1/TUSC3/SLC39A2/PTPRC/CORO1A	75
BP	GO:0001771	immunological synapse formation	4/2486	14/18670	0.1049	0.312	0.2445	DLG1/MSN/CCL21/DOCK8	4
BP	GO:0003188	heart valve formation	4/2486	14/18670	0.1049	0.312	0.2445	TWIST1/GJA5/SOX9/NOTCH1	4
BP	GO:0006878	cellular copper ion homeostasis	4/2486	14/18670	0.1049	0.312	0.2445	ARF1/ATP7B/MT2A/COX19	4
BP	GO:0006999	nuclear pore organization	4/2486	14/18670	0.1049	0.312	0.2445	TMEM170A/NUP93/NUP153/NUP54	4
BP	GO:0010457	centriole-centriole cohesion	4/2486	14/18670	0.1049	0.312	0.2445	CEP135/ODF2/NIN/NEK2	4
BP	GO:0035435	phosphate ion transmembrane transport	4/2486	14/18670	0.1049	0.312	0.2445	SLC25A3/SLC20A1/ANKH/SLC37A4	4
BP	GO:0036295	cellular response to increased oxygen levels	4/2486	14/18670	0.1049	0.312	0.2445	PPARG/ATP6V0A2/TMEM199/CAV1	4
BP	GO:0043558	regulation of translational initiation in response to stress	4/2486	14/18670	0.1049	0.312	0.2445	PPP1R15A/PPP1R15B/EIF2AK4/EIF2S1	4
BP	GO:0045651	positive regulation of macrophage differentiation	4/2486	14/18670	0.1049	0.312	0.2445	FADD/CSF1/TGFB1/HCLS1	4
BP	GO:0045836	positive regulation of meiotic nuclear division	4/2486	14/18670	0.1049	0.312	0.2445	SIRT2/PLCB1/WNT5A/MSX1	4
BP	GO:0046606	negative regulation of centrosome cycle	4/2486	14/18670	0.1049	0.312	0.2445	RBM14/MDM1/TMEM67/NEK2	4
BP	GO:0051645	Golgi localization	4/2486	14/18670	0.1049	0.312	0.2445	SLC9A3R1/YWHAZ/PDCD10/UVRAG	4
BP	GO:0051775	response to redox state	4/2486	14/18670	0.1049	0.312	0.2445	SIRT2/SMPD3/FKBP1B/RYR2	4
BP	GO:0060732	positive regulation of inositol phosphate biosynthetic process	4/2486	14/18670	0.1049	0.312	0.2445	SNCA/CD244/PTH1R/HRH1	4
BP	GO:0070307	lens fiber cell development	4/2486	14/18670	0.1049	0.312	0.2445	TMOD1/WNT5B/BFSP1/FRS2	4
BP	GO:0072498	embryonic skeletal joint development	4/2486	14/18670	0.1049	0.312	0.2445	WNT9A/SHOX2/HOXA11/HYAL1	4
BP	GO:0090178	regulation of establishment of planar polarity involved in neural tube closure	4/2486	14/18670	0.1049	0.312	0.2445	SFRP2/SEC24B/SFRP1/WNT5A	4
BP	GO:0099188	postsynaptic cytoskeleton organization	4/2486	14/18670	0.1049	0.312	0.2445	ARF1/WASF2/NEFH/MYH10	4
BP	GO:1901213	regulation of transcription from RNA polymerase II promoter involved in heart development	4/2486	14/18670	0.1049	0.312	0.2445	ACVR1/TBX2/NOTCH1/MSX1	4
BP	GO:1901626	regulation of postsynaptic membrane organization	4/2486	14/18670	0.1049	0.312	0.2445	CRKL/SSH1/PTN/CRIPT	4
BP	GO:1904263	positive regulation of TORC1 signaling	4/2486	14/18670	0.1049	0.312	0.2445	RRAGA/FLCN/TELO2/SIK3	4
BP	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	12/2486	61/18670	0.1049	0.312	0.2445	TNFAIP3/CASP4/CLIP3/SPATA2/TNF/NOL3/HIPK1/GAS6/CYLD/CCDC3/MADD/NR1H4	12
BP	GO:0032370	positive regulation of lipid transport	12/2486	61/18670	0.1049	0.312	0.2445	NFKBIA/GHRL/CYP4F2/SIRT1/SPP1/P2RX7/TNFRSF11A/C1QTNF1/IL1B/TRIAP1/PLTP/FABP3	12
BP	GO:0050701	interleukin-1 secretion	12/2486	61/18670	0.1049	0.312	0.2445	ORM1/TNFAIP3/ARG2/LPL/GAS6/ZC3H12A/P2RX7/PML/FZD5/NLRP1/WNT5A/NLRP7	12
BP	GO:0071384	cellular response to corticosteroid stimulus	12/2486	61/18670	0.1049	0.312	0.2445	ARG1/TGFB1/ZFP36/AKAP13/EGFR/STC1/ASS1/AQP1/NR3C1/REST/FAM107A/ADCYAP1	12
BP	GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	12/2486	61/18670	0.1049	0.312	0.2445	ARG2/SMAD7/CD83/TWSG1/MIR21/ZC3H12A/IRF4/NFKBIZ/HLX/IL23R/IL2/RC3H1	12
BP	GO:0070588	calcium ion transmembrane transport	50/2486	315/18670	0.105	0.3121	0.2446	SRI/SLC24A3/PDPK1/ITPR1/CACNA2D2/SNCA/MCOLN3/NOL3/TGFB1/PKD2L2/PHB2/FGF14/PDE2A/CACNB3/GAS6/ADRA2A/DIAPH1/FAM155A/CX3CL1/MIR21/P2RY12/PDE4B/DDIT3/STAC/P2RX7/GPR35/CATSPER3/SLC24A5/PLCB2/STAC2/PLCB1/CACNA2D3/AHNAK/RAMP3/APLNR/TMEM37/IBTK/FKBP1B/CCL21/THY1/ANK2/TRPM5/TLR9/SPG7/RYR2/PKD1L2/LYN/DMD/PTPRC/CORO1A	50
BP	GO:0009648	photoperiodism	6/2486	25/18670	0.1054	0.3125	0.245	RBM4/BHLHE40/PML/MTA1/NR2F6/PER1	6
BP	GO:0032461	positive regulation of protein oligomerization	6/2486	25/18670	0.1054	0.3125	0.245	CLU/PMAIP1/MMP1/MMP3/BMF/IDE	6
BP	GO:0032509	endosome transport via multivesicular body sorting pathway	6/2486	25/18670	0.1054	0.3125	0.245	LYST/VPS37A/CHMP1B/VCP/VPS37B/LAPTM4B	6
BP	GO:0045662	negative regulation of myoblast differentiation	6/2486	25/18670	0.1054	0.3125	0.245	TNF/TGFB1/DDIT3/SOX9/NOTCH1/CMTM5	6
BP	GO:0061217	regulation of mesonephros development	6/2486	25/18670	0.1054	0.3125	0.245	TGFB1/SIX1/HOXB7/SMO/SOX9/SIX2	6
BP	GO:1900101	regulation of endoplasmic reticulum unfolded protein response	6/2486	25/18670	0.1054	0.3125	0.245	PPP1R15A/PPP1R15B/ERN1/BAK1/WFS1/HSPA5	6
BP	GO:0055007	cardiac muscle cell differentiation	23/2486	132/18670	0.1055	0.3125	0.245	ARID1A/ACVR1/YY1/TBX5/TGFB1/KDM6B/AKAP13/BMP2/SGCD/OBSL1/IGF1/PDGFRA/ALPK3/EFNB2/FRS2/PDGFRB/NOX4/SGCB/ALPK2/MTOR/MYH10/SOX6/PIN1	23
BP	GO:0002088	lens development in camera-type eye	15/2486	80/18670	0.1056	0.3126	0.245	MAF/TMOD1/DLG1/WNT5B/TGFB1/HIPK1/CDKN1C/SKIL/BCAR3/SIX5/CDON/BFSP1/FRS2/WNT5A/CRYAB	15
BP	GO:0009145	purine nucleoside triphosphate biosynthetic process	29/2486	172/18670	0.1059	0.3134	0.2456	SLC4A1/NUP93/TGFB1/PINK1/PFKFB2/LDHC/DHTKD1/FLCN/ZBTB7A/NUP50/NME5/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/VCP/RAE1/NUP188/NUP160/NUP54/NUP214/NUP155/FOXK2/NUPR1/SLC2A6/PRKAG2/TREM2/PFKP	29
BP	GO:0001678	cellular glucose homeostasis	26/2486	152/18670	0.1062	0.3141	0.2462	SRI/LRP5L/TRA2B/CDK16/GHRL/RAB11FIP5/C2CD2L/GAS6/ERN1/ADRA2A/RAF1/IGF1R/SIRT1/JAGN1/GJB6/IRS2/FOXK2/POLG/STX4/FKBP1B/PPP3CB/NOX4/UNC13B/NR1H4/LRP5/SIN3A	26
BP	GO:0051480	regulation of cytosolic calcium ion concentration	56/2486	357/18670	0.1069	0.3157	0.2475	SRI/PDPK1/ITPR1/EDNRB/GTF2I/SNCA/MCOLN3/NOL3/SPPL3/GHRL/TGFB1/LPAR6/CACNB3/TACR1/DIAPH1/FAM155A/CX3CL1/CXCR1/BDKRB2/GPR4/PTGER4/DDIT3/P2RX7/LPAR4/MCHR1/GPR35/PML/PLCB2/PTH1R/PTGFR/PLCB1/PDGFRA/KCNA5/AGTR1/C1QTNF1/IL2/RAMP3/APLNR/KCNK3/CIB2/IBTK/FKBP1B/CCL21/THY1/ANK2/OXTR/WNT5A/P2RY8/RYR2/CAV1/LYN/BAK1/ADCYAP1/DMD/PTPRC/CORO1A	56
BP	GO:1901184	regulation of ERBB signaling pathway	17/2486	93/18670	0.1069	0.3157	0.2475	SPRY2/SPRY1/FBXW7/ADRA2A/MIR21/CHMP6/ARHGEF7/EGFR/RHBDF1/EGF/CBL/CEACAM1/MMP9/AFAP1L2/IFI6/SH3TC2/PDE6G	17
BP	GO:0002090	regulation of receptor internalization	11/2486	55/18670	0.1071	0.3157	0.2475	ITGB3/NTF3/ARF1/ANKRD13D/ANKRD13B/ANKRD13A/EGF/SFRP4/EFNB2/MAGI2/ARC	11
BP	GO:0010823	negative regulation of mitochondrion organization	11/2486	55/18670	0.1071	0.3157	0.2475	CLU/BAG4/SLC25A5/FXN/NOL3/VAT1/PINK1/FLCN/BCL2L1/IGF1/TRIAP1	11
BP	GO:0042306	regulation of protein import into nucleus	11/2486	55/18670	0.1071	0.3157	0.2475	RBM22/TGFB1/NOLC1/ZC3H12A/JUP/NUP54/SMO/GLI3/IPO5/FLNA/HCLS1	11
BP	GO:0044273	sulfur compound catabolic process	11/2486	55/18670	0.1071	0.3157	0.2475	IDS/CDO1/GGT5/BGN/DCN/ACAN/OGN/CSPG4/FMOD/PRELP/HYAL1	11
BP	GO:0044380	protein localization to cytoskeleton	11/2486	55/18670	0.1071	0.3157	0.2475	RTKN/APC/ANLN/DIAPH1/CEP192/CRIPT/TTBK2/MID1/C2CD3/PARD6A/TTK	11
BP	GO:0002286	T cell activation involved in immune response	19/2486	106/18670	0.1072	0.3157	0.2475	CD1C/EIF2AK4/SMAD7/FCGR2B/MIR21/ZC3H12A/IRF4/NFKBIZ/HLX/PTGER4/IL23R/BATF/CEACAM1/ITGAL/TMEM98/IL2/MTOR/SPN/RC3H1	19
BP	GO:1904029	regulation of cyclin-dependent protein kinase activity	19/2486	106/18670	0.1072	0.3157	0.2475	TNFAIP3/CCNL1/APC/CDKN1C/IPO7/CCND1/CDKN2C/EGFR/CCNT2/CCNYL2/NR2F2/CNTD2/CCNY/PLK1/CDKN2B/CDK5R1/IPO5/HSP90AB1/CDKN3	19
BP	GO:0034765	regulation of ion transmembrane transport	74/2486	483/18670	0.1077	0.317	0.2485	KCNK17/SRI/ANXA3/SCN1B/SLC9A3R1/KCNC4/PDPK1/STOM/ARF1/CNIH3/CACNA2D2/SNCA/TWIST1/DLG1/KCNJ15/ATP1B2/TGFB1/PINK1/PHB2/FGF14/CACNB3/ADRA2A/DIAPH1/GJA5/CX3CL1/DLG2/KCNA6/MIR21/PDE4B/EDN3/GRIA3/KCND3/STAC/P2RX7/HECW2/GPR35/CLIC6/CATSPER3/KCNK10/STAC2/UTRN/MMP9/IRS2/KCNA5/CACNA2D3/AHNAK/KCNMA1/RAMP3/FXYD1/APLNR/HVCN1/KCNJ8/KCNK6/TMEM37/KCNA1/FKBP1B/THY1/TREM2/ANK2/SHISA8/TRPM5/FLNA/TLR9/RYR2/CAV1/MTOR/LYN/KCNS3/DMD/ARC/EPHB2/CORO1A/SHANK3/KCNA3	74
BP	GO:0070838	divalent metal ion transport	74/2486	483/18670	0.1077	0.317	0.2485	CNNM4/SRI/SLC24A3/PDPK1/CAMK2G/ITPR1/PRKCB/CACNA2D2/SNCA/MCOLN3/NOL3/TGFB1/PKD2L2/PHB2/FGF14/PDE2A/CACNB3/GAS6/ADRA2A/DIAPH1/FAM155A/CX3CL1/MIR21/P2RY12/MMGT1/PDE4B/GJA4/DDIT3/CALCRL/STAC/NOS3/STC1/P2RX7/MCHR1/GPR35/PML/CXCL12/CATSPER3/SLC24A5/PLCB2/EGF/STAC2/RAMP2/PLCB1/SLC30A6/CACNA2D3/AHNAK/RAMP3/APLNR/PDGFRB/TMEM37/NIPAL2/IBTK/FKBP1B/CCL21/THY1/ANK2/TRPM5/TLR9/SPG7/CCL8/RYR2/PKD1L2/CAV1/STC2/LYN/BAK1/SLC30A9/DMD/WFS1/TUSC3/SLC39A2/PTPRC/CORO1A	74
BP	GO:0023061	signal release	71/2486	462/18670	0.1079	0.3173	0.2487	SRI/LRP5L/SYTL4/KCNC4/CAMK2G/ITPR1/CDK16/INHBA/STX2/SLC25A5/PRKCB/CACNA2D2/SNCA/SNX19/TNF/GHRL/SCT/SERP1/TRH/RAB11FIP1/PFKFB2/RAB11FIP5/CREB1/C2CD2L/ICA1/STXBP1/ADRA2A/SMPD3/RAF1/RAPGEF3/BTK/EDN3/SPP1/JAGN1/TM7SF3/EGFR/P2RX7/NAAA/CPE/SLC25A6/CADPS2/IRS2/KCNA5/AGTR1/C1QTNF1/PDZD11/BMP8A/SLC32A1/SNAP23/IL1B/STX4/FKBP1B/SFRP1/PPP3CB/PSMD9/REST/CAPN10/LYN/ADCYAP1/KCNS3/FZD4/MIDN/UNC13B/LTBP4/GIPC1/NR1H4/LRP5/PRRT2/RAPGEF4/SYT11/ABAT	71
BP	GO:0006816	calcium ion transport	67/2486	434/18670	0.108	0.3173	0.2487	SRI/SLC24A3/PDPK1/CAMK2G/ITPR1/PRKCB/CACNA2D2/SNCA/MCOLN3/NOL3/TGFB1/PKD2L2/PHB2/FGF14/PDE2A/CACNB3/GAS6/ADRA2A/DIAPH1/FAM155A/CX3CL1/MIR21/P2RY12/PDE4B/GJA4/DDIT3/CALCRL/STAC/NOS3/STC1/P2RX7/MCHR1/GPR35/PML/CXCL12/CATSPER3/SLC24A5/PLCB2/EGF/STAC2/RAMP2/PLCB1/CACNA2D3/AHNAK/RAMP3/APLNR/PDGFRB/TMEM37/IBTK/FKBP1B/CCL21/THY1/ANK2/TRPM5/TLR9/SPG7/CCL8/RYR2/PKD1L2/CAV1/STC2/LYN/BAK1/DMD/WFS1/PTPRC/CORO1A	67
BP	GO:0035304	regulation of protein dephosphorylation	24/2486	139/18670	0.108	0.3173	0.2487	PPP1R15A/PPP1R15B/HSP90B1/TNF/SPPL3/TGFB1/PINK1/PHACTR4/RCAN2/PPP2R5E/PTN/PDGFRB/FKBP1B/MAGI2/CD300A/CDH5/HSP90AB1/MTOR/DLC1/SET/STYXL1/PTPRC/IGFBP3/PIN1	24
BP	GO:0050715	positive regulation of cytokine secretion	24/2486	139/18670	0.108	0.3173	0.2487	ORM1/MMP8/MBP/MAPK11/TRIM6/TNF/TWIST1/LPL/DHX9/CD244/PTGER4/IFIH1/P2RX7/TNFRSF14/CD34/IL1B/IL33/FZD5/NLRP1/WNT5A/IL26/POSTN/FRMD8/NLRP7	24
BP	GO:0002673	regulation of acute inflammatory response	27/2486	159/18670	0.1082	0.3176	0.249	CLU/PROS1/C1QB/C1QA/C1QC/CR1L/EDNRB/CFH/PPARG/TNF/CD59/C2/CFB/RHBDD3/FCGR2B/BTK/SERPING1/CFHR2/CPN1/TNFRSF11A/OSMR/C1R/IL1B/C1S/ADCYAP1/CFI/A2M	27
BP	GO:0086001	cardiac muscle cell action potential	14/2486	74/18670	0.1088	0.3181	0.2493	SCN1B/FGF13/DLG1/GJA5/JUP/KCND3/KCNA5/NUP155/KCNJ8/ANK2/FLNA/RYR2/CAV1/DMD	14
BP	GO:0002704	negative regulation of leukocyte mediated immunity	10/2486	49/18670	0.1089	0.3181	0.2493	PARP3/ARG1/SMAD7/FCGR2B/CEACAM1/IL13RA2/SERPINB9/PPP3CB/CD300A/PTPRC	10
BP	GO:0030857	negative regulation of epithelial cell differentiation	10/2486	49/18670	0.1089	0.3181	0.2493	HOXA7/HES1/CCND1/MMP9/SMO/SOX9/NOTCH1/YAP1/CAV1/FOXJ2	10
BP	GO:0034260	negative regulation of GTPase activity	10/2486	49/18670	0.1089	0.3181	0.2493	SPRY2/RTKN/SPRY1/MIR21/FZD10/IPO5/SLIT2/ADCYAP1/GPSM1/CPEB2	10
BP	GO:0045010	actin nucleation	10/2486	49/18670	0.1089	0.3181	0.2493	ARF1/AP1AR/LMOD1/WHAMM/WASF1/FCHSD2/NCKAP1/ARPC2/CORO1A/MAGEL2	10
BP	GO:0060042	retina morphogenesis in camera-type eye	10/2486	49/18670	0.1089	0.3181	0.2493	HIPK1/THRB/PTN/ROM1/SDK1/CDON/SOX9/THY1/MAN2A1/LRP5	10
BP	GO:0002724	regulation of T cell cytokine production	7/2486	31/18670	0.109	0.3181	0.2493	ARG1/SMAD7/IL1R1/TRAF6/IL1B/FZD5/RSAD2	7
BP	GO:0033687	osteoblast proliferation	7/2486	31/18670	0.109	0.3181	0.2493	GATA1/TMEM119/LTF/BMP2/CTHRC1/SFRP1/JUNB	7
BP	GO:0040018	positive regulation of multicellular organism growth	7/2486	31/18670	0.109	0.3181	0.2493	CSF1/NIPBL/GHRL/CREB1/FOXS1/SMO/GHR	7
BP	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	7/2486	31/18670	0.109	0.3181	0.2493	FBXW7/ADRA2A/EGF/CBL/MMP9/AFAP1L2/PDE6G	7
BP	GO:0050685	positive regulation of mRNA processing	7/2486	31/18670	0.109	0.3181	0.2493	TRA2B/SF3B4/RBM3/RBMXL1/TRA2A/CPEB1/RBMX	7
BP	GO:0086011	membrane repolarization during action potential	7/2486	31/18670	0.109	0.3181	0.2493	DLG1/CACNB3/KCND3/KCNA5/KCNJ8/FLNA/CAV1	7
BP	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	7/2486	31/18670	0.109	0.3181	0.2493	CLU/MUC1/SIRT1/BCL2L1/SFRP2/CXCL12/TRIAP1	7
BP	GO:0046031	ADP metabolic process	22/2486	126/18670	0.1096	0.3196	0.2505	SLC4A1/NUP93/PFKFB2/DHTKD1/ZBTB7A/NUP50/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/RAE1/NUP188/NUP160/NUP54/NUP214/NUP155/FOXK2/NUPR1/SLC2A6/PRKAG2/PFKP	22
BP	GO:0002526	acute inflammatory response	36/2486	220/18670	0.1097	0.3198	0.2507	CLU/PROS1/C1QB/C1QA/C1QC/ORM1/ACVR1/CR1L/EDNRB/CFH/PPARG/TNF/CD59/ELANE/C2/CFB/RHBDD3/FCGR2B/FN1/BTK/SERPING1/F8/CFHR2/HP/ASS1/CPN1/TNFRSF11A/OSMR/C1R/NUPR1/SERPINA3/IL1B/C1S/ADCYAP1/CFI/A2M	36
BP	GO:0006775	fat-soluble vitamin metabolic process	9/2486	43/18670	0.11	0.3199	0.2508	CYP11A1/TNF/CYP4F2/CYP26B1/CRABP1/IL1B/ALDH1A2/PLTP/RBP1	9
BP	GO:0032459	regulation of protein oligomerization	9/2486	43/18670	0.11	0.3199	0.2508	CLU/PMAIP1/EP300/MMP1/SORL1/MMP3/BMF/IDE/CRYAB	9
BP	GO:0032881	regulation of polysaccharide metabolic process	9/2486	43/18670	0.11	0.3199	0.2508	TGFB1/SMPD3/IGF1/EGF/IRS2/KHK/HAS2/SORBS1/MTOR	9
BP	GO:0034198	cellular response to amino acid starvation	9/2486	43/18670	0.11	0.3199	0.2508	RRAGA/MAP1LC3A/DEPDC5/EIF2AK4/EIF2S1/SESN2/MAP3K5/SESN3/MTOR	9
BP	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	9/2486	43/18670	0.11	0.3199	0.2508	SLC9A3R1/PARD3/DLG1/DLG2/MSN/ANK1/FAT1/PDZD11/WNT5A	9
BP	GO:0014037	Schwann cell differentiation	8/2486	37/18670	0.1102	0.3199	0.2508	SIRT2/MPP5/PARD3/NTRK2/RELA/LGI4/GPC1/SH3TC2	8
BP	GO:0032885	regulation of polysaccharide biosynthetic process	8/2486	37/18670	0.1102	0.3199	0.2508	TGFB1/SMPD3/IGF1/EGF/IRS2/HAS2/SORBS1/MTOR	8
BP	GO:0038083	peptidyl-tyrosine autophosphorylation	8/2486	37/18670	0.1102	0.3199	0.2508	BMX/ACE/IGF1R/BTK/EGFR/CAV1/LYN/KDR	8
BP	GO:1903432	regulation of TORC1 signaling	8/2486	37/18670	0.1102	0.3199	0.2508	RRAGA/DEPDC5/FLCN/TELO2/SESN2/SMCR8/SESN3/SIK3	8
BP	GO:2000403	positive regulation of lymphocyte migration	8/2486	37/18670	0.1102	0.3199	0.2508	FADD/ITGA4/CXCL12/TNFRSF14/CCL21/WNT5A/SPN/DOCK8	8
BP	GO:0001892	embryonic placenta development	16/2486	87/18670	0.1106	0.3209	0.2515	ZFAT/HES1/CDKN1C/SP3/EGFR/VASH1/STK4/NR2F2/RSPO3/FZD5/BPTF/E2F8/SPINT2/JUNB/SETD2/NCOA1	16
BP	GO:0051260	protein homooligomerization	55/2486	351/18670	0.1107	0.3209	0.2515	CLU/GNMT/KCNC4/STOM/ARG1/OLFM4/APC/MFF/TAF10/BCL10/LCN2/FUS/ATL2/VWF/SAMHD1/KCNA6/SMPD3/HSF4/PAM/G3BP2/ANGPTL4/RNF213/GCH1/KCND3/DERL1/HINT3/ACOT13/VCP/JMJD6/SLC1A1/DGKD/NUP54/KCNA5/DPYSL3/BMF/C1QTNF1/IDE/TK1/ALDH1A3/KCNA1/ALDH1A2/RBMX/COLEC12/CAV1/TNFAIP1/KCNS3/ARC/ATXN10/CRYAB/SLC6A1/LY6G5C/CRYZ/SYT11/KCNA3/PFKP	55
BP	GO:0055024	regulation of cardiac muscle tissue development	18/2486	100/18670	0.1111	0.322	0.2524	YY1/MAPK11/TBX5/TGFB1/CREB1/BMP2/IGF1/MIR17HG/EFNB2/FRS2/TBX2/NOTCH1/YAP1/JARID2/ZFPM2/MTOR/SOX6/PIN1	18
BP	GO:0031343	positive regulation of cell killing	13/2486	68/18670	0.112	0.3243	0.2542	FAM49B/CD1C/FADD/ARG1/PGLYRP1/CD1B/IL23R/VAV1/P2RX7/HLA-B/IL12A/PTPRC/HLA-A	13
BP	GO:0045806	negative regulation of endocytosis	13/2486	68/18670	0.112	0.3243	0.2542	ANKRD13D/UNC119/TGFB1/PACSIN1/FCGR2B/ANKRD13B/APOC1/ANKRD13A/LRSAM1/CD300LF/CD300A/CAV1/SYT11	13
BP	GO:0031145	anaphase-promoting complex-dependent catabolic process	15/2486	81/18670	0.1144	0.331	0.2594	PSMD14/PSMD12/PSMD7/PSMB5/UBA52/UBE2S/BUB1B/ANAPC10/PSMB7/PLK1/UBE2C/PSMD1/PSMD9/UBC/PSME1	15
BP	GO:0033238	regulation of cellular amine metabolic process	15/2486	81/18670	0.1144	0.331	0.2594	PSMD14/PSMD12/SNCA/PSMD7/PSMB5/MIR21/PSMB7/PSMD1/PSMD9/NR4A2/AZIN1/PSME1/NR1H4/NQO1/ABAT	15
BP	GO:0009185	ribonucleoside diphosphate metabolic process	24/2486	140/18670	0.1147	0.3316	0.2599	SLC4A1/DLG1/NUP93/PFKFB2/DHTKD1/DLG2/ZBTB7A/NUP50/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/RAE1/NUP188/NUP160/NUP54/NUP214/NUP155/FOXK2/NUPR1/SLC2A6/PRKAG2/PFKP	24
BP	GO:0043502	regulation of muscle adaptation	19/2486	107/18670	0.1149	0.3316	0.2599	CAMK2G/YY1/NOL3/CDK9/LMCD1/MIR21/GTF2IRD1/NOS3/IGF1/UTRN/MIR17HG/IGFBP5/KLF4/NOTCH1/JARID2/MIR214/MTOR/MTMR4/PIN1	19
BP	GO:0051341	regulation of oxidoreductase activity	19/2486	107/18670	0.1149	0.3316	0.2599	DDAH1/SNCA/TNF/FXN/PHB2/CYGB/HSP90AA1/MIR21/GCH1/EGFR/AOC3/NOS3/ACVR2A/HP/NOSTRIN/AGTR1/PDP1/IL1B/CAV1	19
BP	GO:0062014	negative regulation of small molecule metabolic process	19/2486	107/18670	0.1149	0.3316	0.2599	EP300/SNCA/TGFB1/ERLIN1/MIR21/SMPD3/FLCN/BMP2/APOC1/SIRT1/ERLIN2/CBFA2T3/CEACAM1/NUPR1/REST/WDTC1/MST1/DKK3/NR1H4	19
BP	GO:0006521	regulation of cellular amino acid metabolic process	12/2486	62/18670	0.1151	0.3318	0.26	PSMD14/PSMD12/PSMD7/PSMB5/MIR21/PSMB7/PSMD1/PSMD9/AZIN1/PSME1/NR1H4/NQO1	12
BP	GO:0009880	embryonic pattern specification	12/2486	62/18670	0.1151	0.3318	0.26	SIM2/MEOX1/NRP1/PCSK6/SMAD1/SATB2/HOXD8/FRS2/MEOX2/C2CD3/FZD5/WNT5A	12
BP	GO:0048857	neural nucleus development	12/2486	62/18670	0.1151	0.3318	0.26	SIRT2/MBP/NFIB/SEC16A/SEC24B/ALDH1A3/CDK5R1/SYPL2/SUDS3/HSPA5/MAPKAP1/ZNF430	12
BP	GO:0055025	positive regulation of cardiac muscle tissue development	12/2486	62/18670	0.1151	0.3318	0.26	TBX5/TGFB1/CREB1/IGF1/MIR17HG/EFNB2/TBX2/NOTCH1/YAP1/ZFPM2/MTOR/PIN1	12
BP	GO:0045621	positive regulation of lymphocyte differentiation	17/2486	94/18670	0.1152	0.3318	0.26	INPP5D/PPP2R3C/DUSP10/TGFB1/GAS6/CD83/MIR21/NFKBIZ/HLX/BTK/IL23R/CYLD/IL12A/IL2/GLI3/PTPRC/AXL	17
BP	GO:0033209	tumor necrosis factor-mediated signaling pathway	28/2486	167/18670	0.1162	0.3337	0.2615	PSMD14/PSMD12/TNFAIP3/CASP4/BAG4/CLIP3/SPATA2/NFKBIA/TNF/NOL3/PSMD7/PSMB5/HIPK1/GAS6/MAP3K14/PLVAP/CYLD/RELA/TNFRSF11A/CCDC3/PSMB7/TNFRSF14/PSMD1/PSMD9/LIMS1/MADD/PSME1/NR1H4	28
BP	GO:0002577	regulation of antigen processing and presentation	5/2486	20/18670	0.117	0.3337	0.2615	FCGR2B/TAPBPL/YTHDF1/CCL21/TREM2	5
BP	GO:0010002	cardioblast differentiation	5/2486	20/18670	0.117	0.3337	0.2615	TBX5/TGFB2/TBX2/NOTCH1/REST	5
BP	GO:0010592	positive regulation of lamellipodium assembly	5/2486	20/18670	0.117	0.3337	0.2615	WASF2/AKIRIN1/NCKAP1/ARPC2/MTOR	5
BP	GO:0030220	platelet formation	5/2486	20/18670	0.117	0.3337	0.2615	EP300/GATA1/TAL1/ACTN1/MYH9	5
BP	GO:0032495	response to muramyl dipeptide	5/2486	20/18670	0.117	0.3337	0.2615	TNFAIP3/NFKBIA/RELA/NOTCH1/NLRP1	5
BP	GO:0033630	positive regulation of cell adhesion mediated by integrin	5/2486	20/18670	0.117	0.3337	0.2615	TGFB2/P2RY12/SFRP2/CCL21/PODXL	5
BP	GO:0034104	negative regulation of tissue remodeling	5/2486	20/18670	0.117	0.3337	0.2615	INPP5D/TNFAIP3/TMEM119/P2RX7/SFRP1	5
BP	GO:0042228	interleukin-8 biosynthetic process	5/2486	20/18670	0.117	0.3337	0.2615	TNF/BCL10/ELANE/KLF4/TLR9	5
BP	GO:0042474	middle ear morphogenesis	5/2486	20/18670	0.117	0.3337	0.2615	SIX1/PRRX1/MSX1/TBX1/SIX2	5
BP	GO:0043371	negative regulation of CD4-positive, alpha-beta T cell differentiation	5/2486	20/18670	0.117	0.3337	0.2615	SMAD7/ZC3H12A/HLX/IL2/RC3H1	5
BP	GO:0043586	tongue development	5/2486	20/18670	0.117	0.3337	0.2615	CYP26B1/EGFR/SIX1/GLI3/TBX1	5
BP	GO:0043931	ossification involved in bone maturation	5/2486	20/18670	0.117	0.3337	0.2615	LTF/BMP2/SEMA4D/IGF1/THBS3	5
BP	GO:0060039	pericardium development	5/2486	20/18670	0.117	0.3337	0.2615	TBX5/BMP2/NOTCH1/WNT5A/SETD2	5
BP	GO:0070932	histone H3 deacetylation	5/2486	20/18670	0.117	0.3337	0.2615	SIRT2/SFPQ/SIRT1/SIRT7/PER1	5
BP	GO:0070987	error-free translesion synthesis	5/2486	20/18670	0.117	0.3337	0.2615	RFC1/UBA52/VCP/RCHY1/UBC	5
BP	GO:0071397	cellular response to cholesterol	5/2486	20/18670	0.117	0.3337	0.2615	GRAMD1B/INHBA/SMO/HMGCS1/GRAMD1C	5
BP	GO:0090195	chemokine secretion	5/2486	20/18670	0.117	0.3337	0.2615	MBP/TNF/LPL/IL33/POSTN	5
BP	GO:1900424	regulation of defense response to bacterium	5/2486	20/18670	0.117	0.3337	0.2615	SIRT2/ARG2/CXCL6/UNC13B/SYT11	5
BP	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	5/2486	20/18670	0.117	0.3337	0.2615	HYOU1/HERPUD1/BCL2L1/CREB3L1/WFS1	5
BP	GO:1905523	positive regulation of macrophage migration	5/2486	20/18670	0.117	0.3337	0.2615	CSF1/AKIRIN1/P2RY12/RARRES2/TREM2	5
BP	GO:0022029	telencephalon cell migration	11/2486	56/18670	0.1181	0.3365	0.2638	FGF13/LHX6/NRP1/P2RY12/EGFR/CXCL12/GLI3/LAMB1/CDK5R1/SLIT2/SUN2	11
BP	GO:0090183	regulation of kidney development	11/2486	56/18670	0.1181	0.3365	0.2638	TGFB1/FLCN/WWTR1/SIX1/HOXB7/MMP9/SMO/PDGFRB/SOX9/YAP1/SIX2	11
BP	GO:0043242	negative regulation of protein complex disassembly	14/2486	75/18670	0.1182	0.3366	0.2638	EPS8/FGF13/TMOD1/NAV3/APC/TNF/CLASP2/AVIL/TTBK2/LMOD1/PLEKHH2/MID1/CAPZA1/CLASP1	14
BP	GO:0010633	negative regulation of epithelial cell migration	20/2486	114/18670	0.1182	0.3366	0.2638	PPARG/DUSP10/TGFB1/MIR21/MMRN2/JUP/STC1/ADAMTS9/CARD10/VASH1/NR2F2/DNAJA4/MEOX2/KLF4/NOTCH1/PTPRG/ANGPT2/PDCD10/DCN/SLIT2	20
BP	GO:0042752	regulation of circadian rhythm	20/2486	114/18670	0.1182	0.3366	0.2638	RBM4/PPARG/GHRL/SFPQ/ARNTL2/BHLHE40/CREB1/FBXW7/KDM2A/USP7/PML/MTA1/KLF10/NR1D2/NR2F6/NONO/MTOR/PER1/SIN3A/MAGEL2	20
BP	GO:1990845	adaptive thermogenesis	26/2486	154/18670	0.119	0.3385	0.2653	GRB10/APC/FABP5/GHRL/SCT/LCN2/SORL1/KDM6B/FLCN/IGF1R/IRF4/GPR3/DDIT3/ADIPOR2/HOXC10/ACOT13/MFAP2/BSCL2/BMP8A/NOTCH1/DIO2/ZNF423/OXTR/EBF2/CAV1/ADCYAP1	26
BP	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	18/2486	101/18670	0.1192	0.3387	0.2655	HLA-DPB1/KIF26A/ARF1/DYNC1I1/ACTR10/FCGR2B/TRAF6/KIF4A/AP2A2/SEC24B/KIF2C/CAPZA1/TREM2/CTSF/DYNLL2/AP1S3/DCTN4/KLC1	18
BP	GO:0046632	alpha-beta T cell differentiation	18/2486	101/18670	0.1192	0.3387	0.2655	IRF1/SMAD7/CD83/MIR21/ZC3H12A/IRF4/NFKBIZ/HLX/PTGER4/IL23R/BATF/TMEM98/IL2/GLI3/MTOR/SPN/RC3H1/RSAD2	18
BP	GO:0006165	nucleoside diphosphate phosphorylation	23/2486	134/18670	0.1193	0.3387	0.2655	SLC4A1/NUP93/PFKFB2/DHTKD1/ZBTB7A/NUP50/NME5/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/RAE1/NUP188/NUP160/NUP54/NUP214/NUP155/FOXK2/NUPR1/SLC2A6/PRKAG2/PFKP	23
BP	GO:0009791	post-embryonic development	16/2486	88/18670	0.1194	0.3387	0.2655	ITPR1/IREB2/SERP1/TIPARP/CSRNP1/KLF4/MFAP2/PLAGL2/FZD5/EFEMP1/NDN/NR4A2/MTOR/BAK1/FBN1/SOX6	16
BP	GO:0034103	regulation of tissue remodeling	16/2486	88/18670	0.1194	0.3387	0.2655	ITGB3/INPP5D/TNFAIP3/TMEM119/TGFB1/SPP1/THBS4/EGFR/P2RX7/TNFRSF11A/CEACAM1/IL2/SFRP1/GPNMB/MIR214/PDK4	16
BP	GO:1900407	regulation of cellular response to oxidative stress	16/2486	88/18670	0.1194	0.3387	0.2655	TNF/NOL3/SFPQ/PINK1/FBXW7/MIR21/PYCR1/SIRT1/GCH1/NME5/HSPB1/MMP3/MCL1/REST/NONO/MAPKAP1	16
BP	GO:0045927	positive regulation of growth	43/2486	270/18670	0.1201	0.3406	0.267	SLC25A33/BDNF/CSF1/NIPBL/TBX5/CACNA2D2/FXN/GHRL/TGFB2/AGRN/RND2/SERP1/CREB1/NRP1/L1CAM/FN1/HLX/EGFR/SFRP2/SEMA4D/IGF1/CXCL12/ITSN2/PLCB1/MIR17HG/FOXS1/IL2/SMO/MTM1/TBX2/NOTCH1/YAP1/SFRP1/ZFPM2/PPM1F/MTOR/GHR/WFS1/PRSS2/N6AMT1/HYAL1/PIN1/GDI1	43
BP	GO:0070663	regulation of leukocyte proliferation	36/2486	222/18670	0.1204	0.3414	0.2676	INPP5D/HLA-DPB1/TNFAIP3/ARG2/FADD/ARG1/CSF1/IRF1/DLG1/TGFB1/IGFBP2/CD276/HES1/FCGR2B/TWSG1/MIR21/BTK/TRAF6/IL23R/IGF1/IRS2/PDCD1LG2/IL12A/IL2/TNFRSF14/IL1B/GPNMB/VAV3/TLR9/CCL8/CD300A/LYN/SPN/RC3H1/PTPRC/CORO1A	36
BP	GO:0032873	negative regulation of stress-activated MAPK cascade	10/2486	50/18670	0.1207	0.3417	0.2678	DLG1/DUSP10/DNAJA1/PINK1/ITCH/CYLD/SFRP2/SFRP1/DUSP1/PER1	10
BP	GO:0070303	negative regulation of stress-activated protein kinase signaling cascade	10/2486	50/18670	0.1207	0.3417	0.2678	DLG1/DUSP10/DNAJA1/PINK1/ITCH/CYLD/SFRP2/SFRP1/DUSP1/PER1	10
BP	GO:1903793	positive regulation of anion transport	10/2486	50/18670	0.1207	0.3417	0.2678	CYP4F2/TRH/STXBP1/P2RX7/TNFRSF11A/IL1B/TRIAP1/FABP3/SLC6A1/ABAT	10
BP	GO:0046718	viral entry into host cell	21/2486	121/18670	0.1213	0.3431	0.2689	ITGB3/ITGB5/CAV2/IFITM3/TRIM21/GAS6/ITCH/EGFR/NUP153/KPNA3/EFNB2/IDE/TNFRSF14/IFITM2/UVRAG/CAV1/GYPA/ITGA2/GPR15/HYAL1/AXL	21
BP	GO:0034249	negative regulation of cellular amide metabolic process	37/2486	229/18670	0.1213	0.3431	0.2689	CLU/ENC1/ORMDL1/RBM4/CNOT8/PAIP2B/EIF2AK4/SNCA/YTHDF2/FXR1/IREB2/SORL1/TNRC6B/ZFP36/EIF2S1/RBM3/LARP1/MIR21/ZC3H12A/PAIP2/ILF3/SESN2/IGF1/IGFBP5/CELF1/CPEB1/BTG2/YTHDF3/RNF139/MRPL13/CNOT7/ORMDL2/SPON1/RC3H1/CNOT1/PIN1/CPEB2	37
BP	GO:0008286	insulin receptor signaling pathway	24/2486	141/18670	0.1216	0.3437	0.2694	GRB10/ATP6V1E1/APC/PRKCB/CAV2/SORL1/GRB14/ATP6V0A2/SMARCC1/ATP6V1G3/IGF1R/SIRT1/SLC2A8/RARRES2/RELA/IRS2/SESN3/IDE/BCAR1/IL1B/SORBS1/KL/PDK4/NR1H4	24
BP	GO:0070585	protein localization to mitochondrion	24/2486	141/18670	0.1216	0.3437	0.2694	ABLIM3/PMAIP1/TIMM23/DNLZ/TOMM20/BAG4/MFF/DNAJA1/TIMM44/PINK1/TIMM10/MOAP1/ARIH2/FBXW7/HSP90AA1/DDIT3/SLC25A6/GRPEL1/YWHAZ/BMF/FZD5/UBE2D3/TP53BP2/PDCD5	24
BP	GO:2000377	regulation of reactive oxygen species metabolic process	32/2486	195/18670	0.122	0.3445	0.27	CLU/HBB/SIRT2/DDAH1/MMP8/ARG2/CD177/SLC25A33/SNCA/TNF/TGFB1/PINK1/PRDX2/HSP90AA1/MIR21/ZC3H12A/GCH1/EGFR/HP/ASS1/MMP3/AGTR1/KLF4/PDGFRB/CD34/ACP5/IL1B/NOX4/HSP90AB1/CAV1/MTOR/CRYAB	32
BP	GO:0055008	cardiac muscle tissue morphogenesis	13/2486	69/18670	0.1221	0.3446	0.2701	SMAD7/TGFB2/TGFB1/TPM1/FOXC1/BMP2/OBSL1/UBE4B/POU4F1/NOTCH1/ZFPM2/WNT5A/RYR2	13
BP	GO:0002360	T cell lineage commitment	6/2486	26/18670	0.1224	0.3446	0.2701	IRF4/IL23R/CYLD/BATF/MTOR/SPN	6
BP	GO:0006779	porphyrin-containing compound biosynthetic process	6/2486	26/18670	0.1224	0.3446	0.2701	ALAS2/UROD/FXN/IREB2/ABCB6/ALAS1	6
BP	GO:0022011	myelination in peripheral nervous system	6/2486	26/18670	0.1224	0.3446	0.2701	SIRT2/MPP5/PARD3/NTRK2/LGI4/SH3TC2	6
BP	GO:0032292	peripheral nervous system axon ensheathment	6/2486	26/18670	0.1224	0.3446	0.2701	SIRT2/MPP5/PARD3/NTRK2/LGI4/SH3TC2	6
BP	GO:0045992	negative regulation of embryonic development	6/2486	26/18670	0.1224	0.3446	0.2701	SFRP2/SULF1/COL5A1/TBX2/WNT5A/COL5A2	6
BP	GO:0050926	regulation of positive chemotaxis	6/2486	26/18670	0.1224	0.3446	0.2701	NTF3/VEGFC/CXCL12/ANGPT2/KDR/ITGA2	6
BP	GO:0060669	embryonic placenta morphogenesis	6/2486	26/18670	0.1224	0.3446	0.2701	CDKN1C/RSPO3/FZD5/SPINT2/SETD2/NCOA1	6
BP	GO:0050806	positive regulation of synaptic transmission	28/2486	168/18670	0.1226	0.3447	0.2702	MME/EIF2AK4/SNCA/SQSTM1/TNF/CUX2/SLC1A3/SSH1/PINK1/CREB1/CACNB3/STXBP1/YTHDF1/NFATC4/EGFR/NTRK2/PTN/STX4/OXTR/FAM107A/RGS14/ADCYAP1/ARC/UNC13B/STAU1/EPHB2/SHANK3/ABAT	28
BP	GO:0014047	glutamate secretion	9/2486	44/18670	0.1229	0.3452	0.2705	SNCA/SLC1A3/TRH/STXBP1/NTRK2/P2RX7/SLC1A1/UNC13B/GIPC1	9
BP	GO:0046189	phenol-containing compound biosynthetic process	9/2486	44/18670	0.1229	0.3452	0.2705	ASIP/SNCA/TGFB2/GCH1/SLC24A5/WNT5A/NR4A2/PNMT/GIPC1	9
BP	GO:0046916	cellular transition metal ion homeostasis	19/2486	108/18670	0.1229	0.3452	0.2705	ALAS2/SRI/ARF1/ATP7B/LTF/FXN/IREB2/LCN2/ABCB6/ABCG2/ATP6V0A2/MT2A/COX19/ABCB7/TMEM199/CP/SLC30A9/HEPH/CUL1	19
BP	GO:0055117	regulation of cardiac muscle contraction	15/2486	82/18670	0.1237	0.346	0.2712	SRI/FGF13/SMAD7/DLG1/GJA5/ZC3H12A/PDE4B/JUP/STC1/FKBP1B/ANK2/FLNA/RYR2/CAV1/DMD	15
BP	GO:1905954	positive regulation of lipid localization	15/2486	82/18670	0.1237	0.346	0.2712	NFKBIA/LPL/GHRL/CYP4F2/ZC3H12A/MSR1/SIRT1/SPP1/P2RX7/TNFRSF11A/C1QTNF1/IL1B/TRIAP1/PLTP/FABP3	15
BP	GO:0051651	maintenance of location in cell	17/2486	95/18670	0.1238	0.346	0.2712	SRI/VPS13C/PINK1/SORL1/JUP/PML/TAF3/PFN4/TMSB4Y/KDELR3/UVRAG/TMSB15A/RANGAP1/CAV1/HSPA5/BARD1/SUN2	17
BP	GO:0010595	positive regulation of endothelial cell migration	22/2486	128/18670	0.1241	0.346	0.2712	ITGB3/ANXA3/PDPK1/SPARC/VEGFC/TGFB1/NRP1/MIR21/ZC3H12A/FGF18/SIRT1/NOS3/HSPB1/SMOC2/RHOJ/SRPX2/BCAR1/TEK/WNT5A/MAP3K3/KDR/CCBE1	22
BP	GO:0032944	regulation of mononuclear cell proliferation	34/2486	209/18670	0.1242	0.346	0.2712	INPP5D/HLA-DPB1/ARG2/FADD/ARG1/CSF1/IRF1/DLG1/TGFB1/IGFBP2/CD276/HES1/FCGR2B/TWSG1/MIR21/BTK/TRAF6/IL23R/IGF1/IRS2/PDCD1LG2/IL12A/IL2/TNFRSF14/IL1B/GPNMB/VAV3/TLR9/CD300A/LYN/SPN/RC3H1/PTPRC/CORO1A	34
BP	GO:0002707	negative regulation of lymphocyte mediated immunity	8/2486	38/18670	0.1242	0.346	0.2712	PARP3/ARG1/SMAD7/FCGR2B/CEACAM1/SERPINB9/PPP3CB/PTPRC	8
BP	GO:0007190	activation of adenylate cyclase activity	8/2486	38/18670	0.1242	0.346	0.2712	ADCY3/ADCY7/ADCY4/RAF1/ADCY6/RXFP2/ADCYAP1/ADORA3	8
BP	GO:0007223	Wnt signaling pathway, calcium modulating pathway	8/2486	38/18670	0.1242	0.346	0.2712	TNRC6B/PLCB2/PLCB1/PPP3CB/FZD5/WNT5A/PDE6G/FZD4	8
BP	GO:0019068	virion assembly	8/2486	38/18670	0.1242	0.346	0.2712	UBA52/VPS37A/CHMP6/CHMP1B/VPS37B/LRSAM1/UBC/DDX6	8
BP	GO:0046329	negative regulation of JNK cascade	8/2486	38/18670	0.1242	0.346	0.2712	DUSP10/DNAJA1/PINK1/ITCH/CYLD/SFRP2/SFRP1/PER1	8
BP	GO:0071604	transforming growth factor beta production	8/2486	38/18670	0.1242	0.346	0.2712	LTBP1/TGFB2/CREB1/CX3CL1/CD34/LAPTM4B/ITGB8/HSP90AB1	8
BP	GO:0086005	ventricular cardiac muscle cell action potential	8/2486	38/18670	0.1242	0.346	0.2712	DLG1/GJA5/JUP/KCND3/KCNJ8/ANK2/RYR2/CAV1	8
BP	GO:1902742	apoptotic process involved in development	8/2486	38/18670	0.1242	0.346	0.2712	TGFB2/JAG2/FOXC1/NOTCH1/FZD5/SLIT2/BAK1/CRYAB	8
BP	GO:0001569	branching involved in blood vessel morphogenesis	7/2486	32/18670	0.1244	0.346	0.2712	ACVR1/NRP1/NFATC4/SFRP2/COL4A1/STK4/SEMA3E	7
BP	GO:0045987	positive regulation of smooth muscle contraction	7/2486	32/18670	0.1244	0.346	0.2712	CTTN/GHRL/MIR21/NPNT/OXTR/ITGA2/ABAT	7
BP	GO:0046685	response to arsenic-containing substance	7/2486	32/18670	0.1244	0.346	0.2712	RBM4/MKNK2/ZC3H12A/ZFAND2A/VCP/ZFAND1/CPEB2	7
BP	GO:0060674	placenta blood vessel development	7/2486	32/18670	0.1244	0.346	0.2712	ARID1A/HES1/VASH1/NR2F2/FZD5/ITGB8/JUNB	7
BP	GO:0071353	cellular response to interleukin-4	7/2486	32/18670	0.1244	0.346	0.2712	KEAP1/ARG1/PML/CD300LF/HSP90AB1/HSPA5/CORO1A	7
BP	GO:0086019	cell-cell signaling involved in cardiac conduction	7/2486	32/18670	0.1244	0.346	0.2712	SCN1B/GJA5/KCNA5/NUP155/ANK2/FLNA/RYR2	7
BP	GO:1903955	positive regulation of protein targeting to mitochondrion	7/2486	32/18670	0.1244	0.346	0.2712	ABLIM3/PINK1/ARIH2/FBXW7/FZD5/UBE2D3/PDCD5	7
BP	GO:2000778	positive regulation of interleukin-6 secretion	7/2486	32/18670	0.1244	0.346	0.2712	MBP/TNF/TWIST1/LPL/DHX9/IFIH1/IL1B	7
BP	GO:0002637	regulation of immunoglobulin production	12/2486	63/18670	0.1259	0.3499	0.2743	PARP3/TNF/TGFB1/FCGR2B/EXOSC3/TRAF6/IL13RA2/IL2/STX4/IL33/TLR9/PTPRC	12
BP	GO:0034394	protein localization to cell surface	12/2486	63/18670	0.1259	0.3499	0.2743	CD177/BDNF/TNF/RAB11FIP5/EGF/GPIHBP1/LRIG2/EMP2/STX4/ANK2/FLNA/HSP90AB1	12
BP	GO:2000401	regulation of lymphocyte migration	12/2486	63/18670	0.1259	0.3499	0.2743	FADD/ITGA4/CRKL/ECM1/CXCL12/MSN/STK10/TNFRSF14/CCL21/WNT5A/SPN/DOCK8	12
BP	GO:0019932	second-messenger-mediated signaling	67/2486	439/18670	0.1273	0.3535	0.2771	SRI/ADCY3/SLC9A3R1/DDAH1/PDPK1/ITPR1/EDNRB/FHL2/PRKAR2A/ADCY7/TNF/PPP2CA/SPPL3/SCT/ADCY4/SELP/PDE2A/AKAP13/ADRA2A/LMCD1/RCAN2/MT2A/P2RY12/GPR3/CXCR1/RAPGEF3/BTK/SGCD/GPR143/NFATC4/PTGER4/EDN3/CALCRL/EGFR/NOS3/ADCY6/P2RX7/RUNDC3A/IGF1/PTH1R/PTGFR/RAMP2/DGKD/AGTR1/HRH1/RAMP3/AQP1/APLNR/SOX9/CALML4/FKBP1B/RXFP2/TREM2/PPP3CB/ANK2/RYR2/MTOR/KDR/ADCYAP1/DMD/DEFB1/PRKAR2B/PTPRC/RAPGEF4/MRAP2/NR5A2/NFATC3	67
BP	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	18/2486	102/18670	0.1277	0.3535	0.2771	TNFAIP3/CCNL1/APC/CDKN1C/IPO7/CCND1/CDKN2C/EGFR/CCNT2/CCNYL2/NR2F2/CNTD2/CCNY/PLK1/CDKN2B/CDK5R1/IPO5/CDKN3	18
BP	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	18/2486	102/18670	0.1277	0.3535	0.2771	HLA-DPB1/KIF26A/ARF1/DYNC1I1/ACTR10/FCGR2B/TRAF6/KIF4A/AP2A2/SEC24B/KIF2C/CAPZA1/TREM2/CTSF/DYNLL2/AP1S3/DCTN4/KLC1	18
BP	GO:0032602	chemokine production	16/2486	89/18670	0.1285	0.3535	0.2771	ARG2/MBP/TNF/TWIST1/LPL/ELANE/CXCL6/KLF4/IL1B/IL33/TREM2/WNT5A/TLR9/POSTN/ADCYAP1/NR1H4	16
BP	GO:0046427	positive regulation of JAK-STAT cascade	16/2486	89/18670	0.1285	0.3535	0.2771	TNF/HES1/CRLF1/PARP9/IL23R/IGF1/IL12A/IL2/NOTCH1/CRLF3/IL26/CD300A/HCLS1/IL10RA/LYN/GHR	16
BP	GO:0006491	N-glycan processing	4/2486	15/18670	0.1286	0.3535	0.2771	GNPTAB/MAN2A2/PRKCSH/MAN2A1	4
BP	GO:0009109	coenzyme catabolic process	4/2486	15/18670	0.1286	0.3535	0.2771	CYP4F2/VCP/CBR3/ALDH1L2	4
BP	GO:0015802	basic amino acid transport	4/2486	15/18670	0.1286	0.3535	0.2771	SLC15A4/ARG1/SLC7A3/SLC25A29	4
BP	GO:0030730	sequestering of triglyceride	4/2486	15/18670	0.1286	0.3535	0.2771	PPARG/TNF/LPL/IL1B	4
BP	GO:0030852	regulation of granulocyte differentiation	4/2486	15/18670	0.1286	0.3535	0.2771	C1QC/INPP5D/CEACAM1/HCLS1	4
BP	GO:0032645	regulation of granulocyte macrophage colony-stimulating factor production	4/2486	15/18670	0.1286	0.3535	0.2771	IL23R/IL1B/IL17D/TLR9	4
BP	GO:0034616	response to laminar fluid shear stress	4/2486	15/18670	0.1286	0.3535	0.2771	SMAD7/TGFB1/ASS1/KLF4	4
BP	GO:0043508	negative regulation of JUN kinase activity	4/2486	15/18670	0.1286	0.3535	0.2771	DUSP10/DNAJA1/SFRP2/SFRP1	4
BP	GO:0044406	adhesion of symbiont to host	4/2486	15/18670	0.1286	0.3535	0.2771	LTF/GAS6/LRRC15/HSP90AB1	4
BP	GO:0045073	regulation of chemokine biosynthetic process	4/2486	15/18670	0.1286	0.3535	0.2771	TNF/ELANE/IL1B/WNT5A	4
BP	GO:0051044	positive regulation of membrane protein ectodomain proteolysis	4/2486	15/18670	0.1286	0.3535	0.2771	TNF/ADRA2A/IL1B/SH3D19	4
BP	GO:0060099	regulation of phagocytosis, engulfment	4/2486	15/18670	0.1286	0.3535	0.2771	PPARG/TREM2/CD300A/ITGA2	4
BP	GO:0060253	negative regulation of glial cell proliferation	4/2486	15/18670	0.1286	0.3535	0.2771	HES1/PTN/NOTCH1/ADCYAP1	4
BP	GO:0070365	hepatocyte differentiation	4/2486	15/18670	0.1286	0.3535	0.2771	TAF10/CPS1/ITGA2/E2F8	4
BP	GO:0071474	cellular hyperosmotic response	4/2486	15/18670	0.1286	0.3535	0.2771	XRCC6/AQP1/RCSD1/EFHD1	4
BP	GO:0090136	epithelial cell-cell adhesion	4/2486	15/18670	0.1286	0.3535	0.2771	ITGB5/PLEKHA7/THBS4/JUP	4
BP	GO:0090141	positive regulation of mitochondrial fission	4/2486	15/18670	0.1286	0.3535	0.2771	MFF/PINK1/DCN/KDR	4
BP	GO:1900029	positive regulation of ruffle assembly	4/2486	15/18670	0.1286	0.3535	0.2771	EPS8/P2RY12/PFN1/EPS8L1	4
BP	GO:1901841	regulation of high voltage-gated calcium channel activity	4/2486	15/18670	0.1286	0.3535	0.2771	SRI/FGF14/CACNB3/PDE4B	4
BP	GO:2001028	positive regulation of endothelial cell chemotaxis	4/2486	15/18670	0.1286	0.3535	0.2771	FGF18/HSPB1/SMOC2/KDR	4
BP	GO:0008016	regulation of heart contraction	40/2486	251/18670	0.1289	0.3541	0.2775	SRI/SCN1B/FGF13/ITPR1/CACNA2D2/MYL4/SMAD7/DLG1/TGFB2/ATP1B2/TPM1/CACNB3/GJA5/ZC3H12A/THRB/PDE4B/EDN3/ASPH/JUP/GCH1/KCND3/NOS3/STC1/SLC1A1/KCNA5/CACNA2D3/IL2/FXYD1/NUP155/KCNK3/TBX2/KCNK6/FKBP1B/ANK2/FLNA/RYR2/CAV1/DMD/KCNK1/ADORA3	40
BP	GO:0140056	organelle localization by membrane tethering	28/2486	169/18670	0.1291	0.3546	0.2779	SCFD1/STX2/CAV2/STX16/B9D1/STX8/STXBP1/HSP90AA1/CEP192/B9D2/CEP135/HAUS8/ODF2/SCLT1/NPHP1/TTBK2/PLK1/STX4/C2CD3/HAUS2/NDE1/SSNA1/CLASP1/TMEM67/RAB8A/UNC13B/PRKAR2B/NEK2	28
BP	GO:0018208	peptidyl-proline modification	11/2486	57/18670	0.1297	0.3556	0.2787	PPIL6/PPIL1/FKBP4/PPID/FKBP10/NKTR/PPIC/FKBP1B/FKBP8/PIN4/PIN1	11
BP	GO:0042743	hydrogen peroxide metabolic process	11/2486	57/18670	0.1297	0.3556	0.2787	HBB/HBD/SNCA/PINK1/PRDX2/PXDN/HBM/EGFR/HP/MMP3/HBQ1	11
BP	GO:1903428	positive regulation of reactive oxygen species biosynthetic process	11/2486	57/18670	0.1297	0.3556	0.2787	CLU/HBB/DDAH1/MMP8/TNF/HSP90AA1/ASS1/KLF4/IL1B/HSP90AB1/MTOR	11
BP	GO:0032868	response to insulin	43/2486	272/18670	0.1304	0.3573	0.2801	GRB10/PDPK1/PPARG/SLC25A33/ATP6V1E1/APC/RAB13/PRKCB/CAV2/LPL/SORL1/GRB14/ATP6V0A2/SMARCC1/ATP6V1G3/IGF1R/SIRT1/SESN2/MAX/SLC2A8/HSD11B2/RARRES2/RELA/CEACAM1/IRS2/SESN3/IDE/BCAR1/CPEB1/KHK/MYO1C/IL1B/SORBS1/WDTC1/CAPN10/MTOR/LYN/RAB8A/KL/PDK4/NR1H4/FABP3/CPEB2	43
BP	GO:0021761	limbic system development	19/2486	109/18670	0.1312	0.3595	0.2818	ANXA3/FGF13/PLXNA3/SCT/CRKL/KDM6B/NRP1/SMO/SLC32A1/MFSD2A/ALDH1A3/KCNA1/GLI3/BTG2/CDK5R1/EMX2/EZH1/KIF14/NCOA1	19
BP	GO:0034754	cellular hormone metabolic process	22/2486	129/18670	0.1317	0.3606	0.2826	CYP11A1/DHRS9/TIPARP/CYP26B1/BMP2/CYP21A2/SPP1/HSD17B14/PDGFRA/HSD17B1/AKR1C2/CRABP1/CYP27C1/ALDH1A3/ALDH1A2/REST/AKR1D1/CYP3A5/HSD17B3/RBP1/DKK3/ADH1C	22
BP	GO:0044106	cellular amine metabolic process	22/2486	129/18670	0.1317	0.3606	0.2826	PSMD14/PSMD12/AMD1/SNCA/PSMD7/PSMB5/TRH/MAOA/MIR21/NAAA/GDPD1/PSMB7/AADAT/PSMD1/PSMD9/NR4A2/AZIN1/PSME1/NR1H4/ALDH7A1/NQO1/ABAT	22
BP	GO:0009127	purine nucleoside monophosphate biosynthetic process	30/2486	183/18670	0.132	0.3609	0.2829	SLC4A1/NUP93/TGFB1/PINK1/PFKFB2/LDHC/DHTKD1/FLCN/ZBTB7A/NUP50/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/VCP/RAE1/NUP188/NUP160/NUP54/NUP214/NUP155/FOXK2/AMPD2/NUPR1/SLC2A6/PRKAG2/TREM2/PFAS/PFKP	30
BP	GO:0009168	purine ribonucleoside monophosphate biosynthetic process	30/2486	183/18670	0.132	0.3609	0.2829	SLC4A1/NUP93/TGFB1/PINK1/PFKFB2/LDHC/DHTKD1/FLCN/ZBTB7A/NUP50/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/VCP/RAE1/NUP188/NUP160/NUP54/NUP214/NUP155/FOXK2/AMPD2/NUPR1/SLC2A6/PRKAG2/TREM2/PFAS/PFKP	30
BP	GO:0045861	negative regulation of proteolysis	56/2486	363/18670	0.1326	0.3621	0.2838	PROS1/SLPI/GABARAPL2/SNCA/CD109/LTF/NOL3/CD59/GAS1/SORL1/TRIM21/IFI16/HERPUD1/GAS6/UBXN1/SMARCC1/RAF1/CLN8/USP7/SERPING1/ECM1/SFRP2/SERPINH1/PML/WFDC1/WAC/TFPI/MMP9/WNT9A/TIMP3/PLAT/LRIG2/TMEM98/IDE/AQP1/KLF4/SERPINB9/MTM1/WFDC3/IFI6/SERPINA3/CAMLG/TIMP4/UBE2G2/HSP90AB1/RPS7/ITIH2/TRIAP1/TAF1/A2M/SPINT2/CRYAB/GIPC1/LXN/RARRES1/NLRP7	56
BP	GO:0007004	telomere maintenance via telomerase	13/2486	70/18670	0.1327	0.3621	0.2838	RFC1/HSP90AA1/DCP2/TELO2/FBXO4/PKIB/CCT8/SMG6/HSP90AB1/MAPKAPK5/TNKS1BP1/NHP2/NEK2	13
BP	GO:0070988	demethylation	13/2486	70/18670	0.1327	0.3621	0.2838	UTY/OTUD4/KDM5D/TDG/KDM6B/HSF4/KDM2A/USP7/JMJD6/JMJD1C/JARID2/CYP3A5/MMACHC	13
BP	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	17/2486	96/18670	0.1328	0.3621	0.2838	PSMD14/PSMD12/ITGB5/PSMD7/PDIA3/PSMB5/ACE/TAPBPL/HLA-B/SEC24B/IDE/PSMB7/SNAP23/PSMD1/PSMD9/PSME1/HLA-A	17
BP	GO:0032755	positive regulation of interleukin-6 production	17/2486	96/18670	0.1328	0.3621	0.2838	MMP8/MBP/TNF/TWIST1/LPL/DHX9/TRAF6/IFIH1/P2RX7/RAB7B/IL1B/IL17D/IL33/WNT5A/TLR9/TBC1D23/ADCYAP1	17
BP	GO:0090277	positive regulation of peptide hormone secretion	17/2486	96/18670	0.1328	0.3621	0.2838	SRI/GHRL/SCT/SERP1/TRH/PFKFB2/C2CD2L/TM7SF3/EGFR/IRS2/STX4/PPP3CB/PSMD9/CAPN10/ADCYAP1/NR1H4/ABAT	17
BP	GO:0045599	negative regulation of fat cell differentiation	10/2486	51/18670	0.1332	0.3631	0.2846	SIRT2/TNF/TGFB1/SIRT1/DDIT3/WWTR1/TGFB1I1/ZFPM2/WNT5A/RUNX1T1	10
BP	GO:0051496	positive regulation of stress fiber assembly	10/2486	51/18670	0.1332	0.3631	0.2846	BAG4/TPM1/NRP1/RAPGEF3/SFRP1/NOX4/PPM1F/MTOR/ARHGEF15/LIMCH1	10
BP	GO:1901879	regulation of protein depolymerization	15/2486	83/18670	0.1334	0.3635	0.2849	EPS8/FGF13/TMOD1/NAV3/APC/CLASP2/ASPH/AVIL/TTBK2/LMOD1/PLEKHH2/MID1/CAPZA1/NES/CLASP1	15
BP	GO:0046939	nucleotide phosphorylation	23/2486	136/18670	0.1341	0.3639	0.2853	SLC4A1/NUP93/PFKFB2/DHTKD1/ZBTB7A/NUP50/NME5/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/RAE1/NUP188/NUP160/NUP54/NUP214/NUP155/FOXK2/NUPR1/SLC2A6/PRKAG2/PFKP	23
BP	GO:0021782	glial cell development	20/2486	116/18670	0.1343	0.3639	0.2853	CLU/C1QA/SIRT2/MPP5/WASF3/PARD3/CD9/TNF/TGFB1/EGFR/NTRK2/LGI4/MXRA8/SMO/IL1B/TREM2/SH3TC2/ROR1/LYN/EIF2B2	20
BP	GO:0045931	positive regulation of mitotic cell cycle	27/2486	163/18670	0.1344	0.3639	0.2853	NIPBL/PBX1/SMC5/TGFB1/TAL1/MTBP/PHB2/HES1/CCND1/SMPD3/EDN3/EGFR/MEIS2/SMOC2/IGF1/EGF/PLCB1/CDC45/KCNA5/PDGFRB/UBE2C/IL1B/PKN2/MIR214/LRP5/HYAL1/SIN3A	27
BP	GO:0035296	regulation of tube diameter	24/2486	143/18670	0.1362	0.3639	0.2853	HBB/EDNRB/ACE/ADRA2A/GJA5/MIR21/FOXC1/GRIP2/BDKRB2/EDN3/GCH1/EGFR/NOS3/ADCY6/P2RY2/KCNA5/AGTR1/HRH1/KCNMA1/CPS1/OXTR/CAV1/ADCYAP1/ACTA2	24
BP	GO:0050880	regulation of blood vessel size	24/2486	143/18670	0.1362	0.3639	0.2853	HBB/EDNRB/ACE/ADRA2A/GJA5/MIR21/FOXC1/GRIP2/BDKRB2/EDN3/GCH1/EGFR/NOS3/ADCY6/P2RY2/KCNA5/AGTR1/HRH1/KCNMA1/CPS1/OXTR/CAV1/ADCYAP1/ACTA2	24
BP	GO:0097746	regulation of blood vessel diameter	24/2486	143/18670	0.1362	0.3639	0.2853	HBB/EDNRB/ACE/ADRA2A/GJA5/MIR21/FOXC1/GRIP2/BDKRB2/EDN3/GCH1/EGFR/NOS3/ADCY6/P2RY2/KCNA5/AGTR1/HRH1/KCNMA1/CPS1/OXTR/CAV1/ADCYAP1/ACTA2	24
BP	GO:0045581	negative regulation of T cell differentiation	9/2486	45/18670	0.1364	0.3639	0.2853	IRF1/SMAD7/PRDX2/MIR21/ZC3H12A/HLX/IL2/GLI3/RC3H1	9
BP	GO:0051928	positive regulation of calcium ion transport	21/2486	123/18670	0.1371	0.3639	0.2853	SRI/PDPK1/SNCA/FGF14/CACNB3/CX3CL1/STAC/STC1/P2RX7/MCHR1/CXCL12/STAC2/RAMP3/APLNR/PDGFRB/THY1/ANK2/RYR2/CAV1/BAK1/WFS1	21
BP	GO:0016445	somatic diversification of immunoglobulins	12/2486	64/18670	0.1373	0.3639	0.2853	MSH6/POLB/PARP3/TGFB1/SAMHD1/EXO1/EXOSC3/BATF/IL2/MCM3AP/PTPRC/RNF8	12
BP	GO:0032768	regulation of monooxygenase activity	12/2486	64/18670	0.1373	0.3639	0.2853	DDAH1/SNCA/TNF/CYGB/HSP90AA1/GCH1/EGFR/NOS3/ACVR2A/NOSTRIN/IL1B/CAV1	12
BP	GO:0046503	glycerolipid catabolic process	12/2486	64/18670	0.1373	0.3639	0.2853	PLA2G4C/DAGLB/FABP5/LPL/SORL1/MGLL/APOC1/GDPD1/CPS1/ENPP2/INPP5F/FABP3	12
BP	GO:0046782	regulation of viral transcription	12/2486	64/18670	0.1373	0.3639	0.2853	EP300/JUN/DHX9/IFITM3/CDK9/TRIM21/ZFP36/CHD1/POLR2G/RSF1/REST/POLR2D	12
BP	GO:1903672	positive regulation of sprouting angiogenesis	12/2486	64/18670	0.1373	0.3639	0.2853	PDPK1/GHRL/NRP1/SMAD1/JAK1/RHOJ/SRPX2/AGTR1/KLF4/APLNR/MAP3K3/KDR	12
BP	GO:0009201	ribonucleoside triphosphate biosynthetic process	29/2486	177/18670	0.1373	0.3639	0.2853	SLC4A1/NUP93/TGFB1/PINK1/PFKFB2/LDHC/DHTKD1/FLCN/ZBTB7A/NUP50/NME5/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/VCP/RAE1/NUP188/NUP160/NUP54/NUP214/NUP155/FOXK2/NUPR1/SLC2A6/PRKAG2/TREM2/PFKP	29
BP	GO:0009713	catechol-containing compound biosynthetic process	5/2486	21/18670	0.1376	0.3639	0.2853	SNCA/TGFB2/GCH1/NR4A2/PNMT	5
BP	GO:0010310	regulation of hydrogen peroxide metabolic process	5/2486	21/18670	0.1376	0.3639	0.2853	SNCA/PINK1/PRDX2/HP/MMP3	5
BP	GO:0010801	negative regulation of peptidyl-threonine phosphorylation	5/2486	21/18670	0.1376	0.3639	0.2853	SIRT2/SPRY2/PARD3/SMAD7/PPEF2	5
BP	GO:0010829	negative regulation of glucose transmembrane transport	5/2486	21/18670	0.1376	0.3639	0.2853	GRB10/PRKCB/TNF/FABP5/IL1B	5
BP	GO:0030277	maintenance of gastrointestinal epithelium	5/2486	21/18670	0.1376	0.3639	0.2853	SOX9/SERPINA3/MUC2/TLR9/ZNF830	5
BP	GO:0030728	ovulation	5/2486	21/18670	0.1376	0.3639	0.2853	INHBA/HPGD/SIRT1/NOS3/MMP19	5
BP	GO:0035743	CD4-positive, alpha-beta T cell cytokine production	5/2486	21/18670	0.1376	0.3639	0.2853	ARG1/IL1R1/IL12A/IL1B/RSAD2	5
BP	GO:0042423	catecholamine biosynthetic process	5/2486	21/18670	0.1376	0.3639	0.2853	SNCA/TGFB2/GCH1/NR4A2/PNMT	5
BP	GO:0043984	histone H4-K16 acetylation	5/2486	21/18670	0.1376	0.3639	0.2853	PHF20/MSL2/WDR5/SIRT1/HCFC1	5
BP	GO:0048245	eosinophil chemotaxis	5/2486	21/18670	0.1376	0.3639	0.2853	CX3CL1/CCL13/DAPK2/HRH1/CCL8	5
BP	GO:0051900	regulation of mitochondrial depolarization	5/2486	21/18670	0.1376	0.3639	0.2853	PPP2R3C/P2RX7/IFI6/DCN/KDR	5
BP	GO:0061213	positive regulation of mesonephros development	5/2486	21/18670	0.1376	0.3639	0.2853	TGFB1/SIX1/HOXB7/SMO/SOX9	5
BP	GO:0072010	glomerular epithelium development	5/2486	21/18670	0.1376	0.3639	0.2853	PTPRO/FOXC1/CD34/MAGI2/PODXL	5
BP	GO:0140058	neuron projection arborization	5/2486	21/18670	0.1376	0.3639	0.2853	GRIP1/NRP1/PTN/WNT5A/FZD4	5
BP	GO:1902473	regulation of protein localization to synapse	5/2486	21/18670	0.1376	0.3639	0.2853	DLG1/GPC4/GPC6/GRASP/WNT5A	5
BP	GO:1903392	negative regulation of adherens junction organization	5/2486	21/18670	0.1376	0.3639	0.2853	ARHGAP6/CLASP2/PHLDB2/FAM107A/DLC1	5
BP	GO:0030901	midbrain development	16/2486	90/18670	0.138	0.3639	0.2853	SIRT2/MBP/HES1/SMAD1/SFRP2/SEC16A/SFRP1/SYPL2/SUDS3/WNT5A/MSX1/NR4A2/TAF1/HSPA5/MAPKAP1/ZNF430	16
BP	GO:0003183	mitral valve morphogenesis	3/2486	10/18670	0.138	0.3639	0.2853	ACVR1/TWIST1/NOTCH1	3
BP	GO:0014041	regulation of neuron maturation	3/2486	10/18670	0.138	0.3639	0.2853	EDNRB/BCL11A/MTOR	3
BP	GO:0015809	arginine transport	3/2486	10/18670	0.138	0.3639	0.2853	ARG1/SLC7A3/SLC25A29	3
BP	GO:0019062	virion attachment to host cell	3/2486	10/18670	0.138	0.3639	0.2853	GAS6/LRRC15/HSP90AB1	3
BP	GO:0032308	positive regulation of prostaglandin secretion	3/2486	10/18670	0.138	0.3639	0.2853	P2RX7/TNFRSF11A/IL1B	3
BP	GO:0032341	aldosterone metabolic process	3/2486	10/18670	0.138	0.3639	0.2853	BMP2/REST/DKK3	3
BP	GO:0032342	aldosterone biosynthetic process	3/2486	10/18670	0.138	0.3639	0.2853	BMP2/REST/DKK3	3
BP	GO:0032353	negative regulation of hormone biosynthetic process	3/2486	10/18670	0.138	0.3639	0.2853	BMP2/REST/DKK3	3
BP	GO:0032875	regulation of DNA endoreduplication	3/2486	10/18670	0.138	0.3639	0.2853	MSH6/FBXW7/E2F8	3
BP	GO:0032926	negative regulation of activin receptor signaling pathway	3/2486	10/18670	0.138	0.3639	0.2853	ACVR1/DACT2/MAGI2	3
BP	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway	3/2486	10/18670	0.138	0.3639	0.2853	COL4A1/COL4A2/DDR2	3
BP	GO:0042989	sequestering of actin monomers	3/2486	10/18670	0.138	0.3639	0.2853	PFN4/TMSB4Y/TMSB15A	3
BP	GO:0043084	penile erection	3/2486	10/18670	0.138	0.3639	0.2853	EDNRB/ACVR2A/OXTR	3
BP	GO:0045713	low-density lipoprotein particle receptor biosynthetic process	3/2486	10/18670	0.138	0.3639	0.2853	ITGB3/PPARG/HNRNPK	3
BP	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity	3/2486	10/18670	0.138	0.3639	0.2853	FBXW7/ADRA2A/EGF	3
BP	GO:0046532	regulation of photoreceptor cell differentiation	3/2486	10/18670	0.138	0.3639	0.2853	THRB/SOX9/NOTCH1	3
BP	GO:0046642	negative regulation of alpha-beta T cell proliferation	3/2486	10/18670	0.138	0.3639	0.2853	ARG2/TWSG1/TNFRSF14	3
BP	GO:0048262	determination of dorsal/ventral asymmetry	3/2486	10/18670	0.138	0.3639	0.2853	ACVR1/DDIT3/GREM2	3
BP	GO:0051124	synaptic growth at neuromuscular junction	3/2486	10/18670	0.138	0.3639	0.2853	AGRN/SIX1/SHANK3	3
BP	GO:0051133	regulation of NK T cell activation	3/2486	10/18670	0.138	0.3639	0.2853	IL23R/IL12A/CD300A	3
BP	GO:0051901	positive regulation of mitochondrial depolarization	3/2486	10/18670	0.138	0.3639	0.2853	P2RX7/DCN/KDR	3
BP	GO:0060068	vagina development	3/2486	10/18670	0.138	0.3639	0.2853	WNT5A/BAK1/AXL	3
BP	GO:0060281	regulation of oocyte development	3/2486	10/18670	0.138	0.3639	0.2853	SIRT2/YTHDF2/IGF1	3
BP	GO:0060346	bone trabecula formation	3/2486	10/18670	0.138	0.3639	0.2853	FBN2/THBS3/SFRP1	3
BP	GO:0060456	positive regulation of digestive system process	3/2486	10/18670	0.138	0.3639	0.2853	GHRL/SCT/AQP1	3
BP	GO:0070099	regulation of chemokine-mediated signaling pathway	3/2486	10/18670	0.138	0.3639	0.2853	SH2B3/TREM2/SLIT2	3
BP	GO:0070472	regulation of uterine smooth muscle contraction	3/2486	10/18670	0.138	0.3639	0.2853	TACR1/OXTR/ABAT	3
BP	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain	3/2486	10/18670	0.138	0.3639	0.2853	CDK9/GTF2H3/CDK13	3
BP	GO:0071233	cellular response to leucine	3/2486	10/18670	0.138	0.3639	0.2853	SESN2/SESN3/MTOR	3
BP	GO:0071670	smooth muscle cell chemotaxis	3/2486	10/18670	0.138	0.3639	0.2853	PDGFRB/SLIT2/PARVA	3
BP	GO:0075522	IRES-dependent viral translational initiation	3/2486	10/18670	0.138	0.3639	0.2853	DENR/EIF3F/PCBP2	3
BP	GO:0090030	regulation of steroid hormone biosynthetic process	3/2486	10/18670	0.138	0.3639	0.2853	BMP2/REST/DKK3	3
BP	GO:0098917	retrograde trans-synaptic signaling	3/2486	10/18670	0.138	0.3639	0.2853	DAGLB/FABP5/PLCB1	3
BP	GO:0150011	regulation of neuron projection arborization	3/2486	10/18670	0.138	0.3639	0.2853	GRIP1/WNT5A/FZD4	3
BP	GO:1902513	regulation of organelle transport along microtubule	3/2486	10/18670	0.138	0.3639	0.2853	TRIM58/NEFH/MAP2	3
BP	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA	3/2486	10/18670	0.138	0.3639	0.2853	TGFB1/ZC3H12A/ZC3H10	3
BP	GO:1903862	positive regulation of oxidative phosphorylation	3/2486	10/18670	0.138	0.3639	0.2853	PINK1/VCP/NUPR1	3
BP	GO:1903897	regulation of PERK-mediated unfolded protein response	3/2486	10/18670	0.138	0.3639	0.2853	PPP1R15A/PPP1R15B/HSPA5	3
BP	GO:1905879	regulation of oogenesis	3/2486	10/18670	0.138	0.3639	0.2853	SIRT2/YTHDF2/IGF1	3
BP	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus	3/2486	10/18670	0.138	0.3639	0.2853	PDPK1/NTRK2/WASF1	3
BP	GO:2000425	regulation of apoptotic cell clearance	3/2486	10/18670	0.138	0.3639	0.2853	C2/CD300LF/TREM2	3
BP	GO:2000574	regulation of microtubule motor activity	3/2486	10/18670	0.138	0.3639	0.2853	MAP2/NDE1/DYNLL2	3
BP	GO:2000628	regulation of miRNA metabolic process	3/2486	10/18670	0.138	0.3639	0.2853	ZC3H12A/RELA/RC3H1	3
BP	GO:2000644	regulation of receptor catabolic process	3/2486	10/18670	0.138	0.3639	0.2853	MYLIP/ITCH/DTX3L	3
BP	GO:2001135	regulation of endocytic recycling	3/2486	10/18670	0.138	0.3639	0.2853	SORL1/EHD2/INPP5F	3
BP	GO:0042445	hormone metabolic process	37/2486	232/18670	0.1384	0.3648	0.2859	MME/CYP11A1/CTSG/DHRS9/TNF/ACE/PCSK6/TIPARP/CYP26B1/BMP2/CYP21A2/SPP1/HSD11B2/CPE/HSD17B14/HSD11B1/GNB3/PDGFRA/HSD17B1/AKR1C2/CRABP1/IDE/CYP27C1/DIO2/ALDH1A3/IL1B/ALDH1A2/REST/AKR1D1/CYP3A5/STC2/HSD17B3/GHR/ENPEP/RBP1/DKK3/ADH1C	37
BP	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	14/2486	77/18670	0.1385	0.3648	0.2859	SIRT2/PSMD14/PSMD12/EP300/PSMD7/PSMB5/UBA52/CREBBP/PSMB7/NOTCH1/PSMD1/PSMD9/UBC/PSME1	14
BP	GO:0048713	regulation of oligodendrocyte differentiation	8/2486	39/18670	0.1391	0.3652	0.2862	PPARG/DUSP10/DAAM2/HES1/PTN/TMEM98/NOTCH1/MTOR	8
BP	GO:0055090	acylglycerol homeostasis	8/2486	39/18670	0.1391	0.3652	0.2862	LPL/MED13/ANGPTL4/SIRT1/SESN2/GPIHBP1/SLC25A27/NR1H4	8
BP	GO:0060306	regulation of membrane repolarization	8/2486	39/18670	0.1391	0.3652	0.2862	SCN1B/DLG1/CACNB3/GJA5/KCNA5/ANK2/FLNA/CAV1	8
BP	GO:0070328	triglyceride homeostasis	8/2486	39/18670	0.1391	0.3652	0.2862	LPL/MED13/ANGPTL4/SIRT1/SESN2/GPIHBP1/SLC25A27/NR1H4	8
BP	GO:0072595	maintenance of protein localization in organelle	8/2486	39/18670	0.1391	0.3652	0.2862	PINK1/PML/TAF3/KDELR3/RANGAP1/HSPA5/BARD1/SUN2	8
BP	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	8/2486	39/18670	0.1391	0.3652	0.2862	FAIM2/TNFAIP3/FADD/RAF1/ITPRIP/BCL2L1/NOS3/SFRP2	8
BP	GO:1902116	negative regulation of organelle assembly	8/2486	39/18670	0.1391	0.3652	0.2862	RBM14/SCFD1/PINK1/MDM1/SMCR8/MTM1/NUPR1/STYXL1	8
BP	GO:1905521	regulation of macrophage migration	8/2486	39/18670	0.1391	0.3652	0.2862	CSF1/CD9/AKIRIN1/P2RY12/RARRES2/MTUS1/TREM2/MST1	8
BP	GO:0016101	diterpenoid metabolic process	19/2486	110/18670	0.1399	0.3659	0.2868	DHRS9/LPL/AGRN/CYP26B1/ABCA4/SDC2/GPC4/EGFR/RARRES2/GPIHBP1/GPC6/CRABP1/CYP27C1/ALDH1A3/ALDH1A2/GPC1/CYP3A5/RBP1/ADH1C	19
BP	GO:0003148	outflow tract septum morphogenesis	6/2486	27/18670	0.1407	0.3659	0.2868	TGFB2/NRP1/TBX2/ZFPM2/TBX1/PARVA	6
BP	GO:0009651	response to salt stress	6/2486	27/18670	0.1407	0.3659	0.2868	XRCC6/TNF/BDKRB2/AQP1/EFHD1/HSP90AB1	6
BP	GO:0036151	phosphatidylcholine acyl-chain remodeling	6/2486	27/18670	0.1407	0.3659	0.2868	PLA2G4C/PLA2G5/LPCAT4/LPCAT3/PLA2G2A/LPCAT1	6
BP	GO:0036336	dendritic cell migration	6/2486	27/18670	0.1407	0.3659	0.2868	EPS8/GAS6/CXCR1/IL12A/CCL21/DOCK8	6
BP	GO:0046885	regulation of hormone biosynthetic process	6/2486	27/18670	0.1407	0.3659	0.2868	TNF/BMP2/IL1B/REST/STC2/DKK3	6
BP	GO:0048143	astrocyte activation	6/2486	27/18670	0.1407	0.3659	0.2868	C1QA/TNF/EGFR/SMO/IL1B/TREM2	6
BP	GO:0048643	positive regulation of skeletal muscle tissue development	6/2486	27/18670	0.1407	0.3659	0.2868	CYP26B1/CDON/MTM1/SHOX2/GPC1/TBX1	6
BP	GO:0048799	animal organ maturation	6/2486	27/18670	0.1407	0.3659	0.2868	LTF/BMP2/SEMA4D/IGF1/THBS3/ALDH1A2	6
BP	GO:0071514	genetic imprinting	6/2486	27/18670	0.1407	0.3659	0.2868	ASIP/ZFP57/CDKN1C/ARID4A/NDN/CTCFL	6
BP	GO:2000191	regulation of fatty acid transport	6/2486	27/18670	0.1407	0.3659	0.2868	CYP4F2/P2RX7/TNFRSF11A/IRS2/IL1B/FABP3	6
BP	GO:0010591	regulation of lamellipodium assembly	7/2486	33/18670	0.1407	0.3659	0.2868	WASF2/AKIRIN1/NCKAP1/MIR214/ARPC2/SLIT2/MTOR	7
BP	GO:0018279	protein N-linked glycosylation via asparagine	7/2486	33/18670	0.1407	0.3659	0.2868	VCP/DDOST/MGAT2/STT3B/UBE2G2/ST6GAL1/TUSC3	7
BP	GO:0036003	positive regulation of transcription from RNA polymerase II promoter in response to stress	7/2486	33/18670	0.1407	0.3659	0.2868	MUC1/HSF4/SESN2/DDIT3/CREB3L1/NOTCH1/HSPA5	7
BP	GO:0042339	keratan sulfate metabolic process	7/2486	33/18670	0.1407	0.3659	0.2868	CHST1/B4GALT2/ACAN/OGN/FMOD/PRELP/B4GALT4	7
BP	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	7/2486	33/18670	0.1407	0.3659	0.2868	LSM4/CNOT8/LSM7/DCP2/EXOSC3/CNOT7/DDX6	7
BP	GO:0050718	positive regulation of interleukin-1 beta secretion	7/2486	33/18670	0.1407	0.3659	0.2868	ORM1/LPL/P2RX7/FZD5/NLRP1/WNT5A/NLRP7	7
BP	GO:0051443	positive regulation of ubiquitin-protein transferase activity	7/2486	33/18670	0.1407	0.3659	0.2868	PINK1/FBXW7/UBE2S/RPS2/PLK1/UBE2C/PIN1	7
BP	GO:0051955	regulation of amino acid transport	7/2486	33/18670	0.1407	0.3659	0.2868	ARG1/SNCA/TRH/STXBP1/P2RX7/SLC6A1/ABAT	7
BP	GO:0060603	mammary gland duct morphogenesis	7/2486	33/18670	0.1407	0.3659	0.2868	LRP5L/CSF1/TGFB1/PHB2/PML/WNT5A/LRP5	7
BP	GO:1901186	positive regulation of ERBB signaling pathway	7/2486	33/18670	0.1407	0.3659	0.2868	FBXW7/ADRA2A/EGF/CBL/MMP9/AFAP1L2/PDE6G	7
BP	GO:1901223	negative regulation of NIK/NF-kappaB signaling	7/2486	33/18670	0.1407	0.3659	0.2868	MIR21/ZC3H12A/CYLD/RELA/TSPAN6/PPM1A/RASSF2	7
BP	GO:1902692	regulation of neuroblast proliferation	7/2486	33/18670	0.1407	0.3659	0.2868	VEGFC/TGFB1/CX3CL1/PTN/SMO/NOTCH1/GLI3	7
BP	GO:1901988	negative regulation of cell cycle phase transition	42/2486	267/18670	0.1408	0.3661	0.2869	MUC1/PSMD14/PSMD12/CRADD/CNOT8/CNOT4/EP300/RPS27L/SYF2/APC/PSMD7/PSMB5/KANK2/CCND1/CTDSPL/CDKN2C/MIR21/MDM4/PML/FOXN3/BUB1B/CDK2AP2/PLK3/PSMB7/KLF4/PLK1/PSMD1/BTG2/CDKN2B/PSMD9/GPNMB/FAM107A/DUSP1/CNOT7/TTK/TRIAP1/TNKS1BP1/E2F8/PSME1/CNOT1/CUL1/ZNF830	42
BP	GO:0006260	DNA replication	43/2486	274/18670	0.1412	0.3666	0.2873	RBM14/MSH6/POLB/PRIM2/RFC1/POLE3/JUN/PPP2CA/CHAF1A/DHX9/CDK9/ZRANB3/SAMHD1/FBXW7/HELB/PTMS/EXO1/NFIB/POLE/WDR18/DDX11/EGFR/SLBP/NFIX/CDC45/DBF4/NAP1L1/RNASEH1/RPAIN/RECQL4/POLG/GINS3/TTF1/SET/TNFAIP1/E2F8/PDS5A/BARD1/NCOA6/SIN3A/ZNF830/ING5/MCM5	43
BP	GO:0032943	mononuclear cell proliferation	43/2486	274/18670	0.1412	0.3666	0.2873	INPP5D/HLA-DPB1/ARG2/FADD/ARG1/CSF1/IRF1/DLG1/TGFB1/IGFBP2/PRDX2/CD276/HES1/ACE/FCGR2B/TWSG1/MIR21/BTK/TRAF6/IL23R/P2RX7/IGF1/MSN/IRS2/PDCD1LG2/IL12A/IL2/TNFRSF14/GAPT/IL1B/FKBP1B/PPP3CB/GPNMB/VAV3/TLR9/CD300A/LYN/SPN/RC3H1/PTPRC/CORO1A/DOCK8/CD151	43
BP	GO:0060048	cardiac muscle contraction	23/2486	137/18670	0.1419	0.3684	0.2887	SRI/SCN1B/MYL4/SMAD7/DLG1/TPM1/GJA5/ZC3H12A/PDE4B/SGCD/JUP/KCND3/STC1/KCNA5/NUP155/KCNJ8/FKBP1B/ANK2/FLNA/RYR2/CAV1/MTOR/DMD	23
BP	GO:0120162	positive regulation of cold-induced thermogenesis	17/2486	97/18670	0.1421	0.3687	0.289	GRB10/APC/FABP5/GHRL/LCN2/KDM6B/IGF1R/IRF4/GPR3/ADIPOR2/MFAP2/BSCL2/DIO2/OXTR/EBF2/CAV1/ADCYAP1	17
BP	GO:0010822	positive regulation of mitochondrion organization	20/2486	117/18670	0.1428	0.3703	0.2903	ABLIM3/PMAIP1/VPS13C/MFF/PINK1/MOAP1/ARIH2/FBXW7/YWHAZ/MMP9/BMF/TREM2/FZD5/UBE2D3/DCN/TP53BP2/BAK1/KDR/PDCD5/CIDEB	20
BP	GO:0051153	regulation of striated muscle cell differentiation	20/2486	117/18670	0.1428	0.3703	0.2903	YY1/BDNF/TMEM119/BHLHE41/TGFB1/AKAP13/CYP26B1/BMP2/EHD2/IGF1/EFNB2/FRS2/MORF4L2/NOTCH1/SHOX2/MSX1/TBX1/MTOR/SOX6/PIN1	20
BP	GO:0010507	negative regulation of autophagy	15/2486	84/18670	0.1435	0.3718	0.2914	SIRT2/RRAGA/SCFD1/HERC1/SNCA/PINK1/SMCR8/BMF/FOXK2/MCL1/MTM1/NUPR1/TREM2/IL10RA/MTOR	15
BP	GO:0097756	negative regulation of blood vessel diameter	15/2486	84/18670	0.1435	0.3718	0.2914	EDNRB/ACE/ADRA2A/GJA5/MIR21/GRIP2/BDKRB2/EDN3/EGFR/KCNA5/AGTR1/HRH1/OXTR/CAV1/ACTA2	15
BP	GO:1904427	positive regulation of calcium ion transmembrane transport	13/2486	71/18670	0.1437	0.3722	0.2917	SRI/PDPK1/SNCA/FGF14/CACNB3/CX3CL1/STAC/STAC2/RAMP3/APLNR/THY1/ANK2/RYR2	13
BP	GO:0035150	regulation of tube size	24/2486	144/18670	0.1439	0.3725	0.292	HBB/EDNRB/ACE/ADRA2A/GJA5/MIR21/FOXC1/GRIP2/BDKRB2/EDN3/GCH1/EGFR/NOS3/ADCY6/P2RY2/KCNA5/AGTR1/HRH1/KCNMA1/CPS1/OXTR/CAV1/ADCYAP1/ACTA2	24
BP	GO:0022406	membrane docking	29/2486	178/18670	0.1442	0.3731	0.2924	SCFD1/STX2/CAV2/STX16/B9D1/STX8/STXBP1/HSP90AA1/CEP192/B9D2/CEP135/HAUS8/MSN/ODF2/SCLT1/NPHP1/TTBK2/PLK1/STX4/C2CD3/HAUS2/NDE1/SSNA1/CLASP1/TMEM67/RAB8A/UNC13B/PRKAR2B/NEK2	29
BP	GO:0014013	regulation of gliogenesis	21/2486	124/18670	0.1455	0.3763	0.2949	SIRT2/PPARG/CSF1/TNF/DUSP10/CRKL/TGFB1/DAAM2/CREB1/HES1/P2RY12/BMP2/RELA/PTN/TMEM98/NOTCH1/IL1B/TREM2/MTOR/LYN/ADCYAP1	21
BP	GO:0001523	retinoid metabolic process	18/2486	104/18670	0.1457	0.3764	0.295	DHRS9/LPL/AGRN/CYP26B1/ABCA4/SDC2/GPC4/RARRES2/GPIHBP1/GPC6/CRABP1/CYP27C1/ALDH1A3/ALDH1A2/GPC1/CYP3A5/RBP1/ADH1C	18
BP	GO:0055088	lipid homeostasis	25/2486	151/18670	0.1457	0.3764	0.295	ORMDL1/LRP5L/GRAMD1B/MYLIP/TLCD2/PPARG/LPL/FBXW7/MALL/MED13/ANGPTL4/SIRT1/SESN2/GPIHBP1/SLC25A27/IRS2/NR1D2/ORMDL2/CAV1/CYP39A1/RBP1/NR1H4/FABP3/LRP5/NR5A2	25
BP	GO:1903169	regulation of calcium ion transmembrane transport	25/2486	151/18670	0.1457	0.3764	0.295	SRI/PDPK1/SNCA/TGFB1/FGF14/CACNB3/ADRA2A/DIAPH1/CX3CL1/MIR21/PDE4B/STAC/GPR35/STAC2/AHNAK/RAMP3/APLNR/FKBP1B/THY1/ANK2/TLR9/RYR2/LYN/DMD/CORO1A	25
BP	GO:0009108	coenzyme biosynthetic process	41/2486	261/18670	0.1462	0.3775	0.2959	PPTC7/PDPR/SLC4A1/SNCA/NUP93/PFKFB2/COQ10B/DHTKD1/PARP9/ZBTB7A/NUP50/GCH1/NNMT/QPRT/P2RX7/PTS/CBFA2T3/IGF1/NUP153/LIAS/NUP210/ELOVL7/RAE1/NUP188/NUP160/NUP54/PDP1/NADSYN1/NUP214/NUP155/FOXK2/NUPR1/SLC2A6/PRKAG2/TPK1/PANK1/MAT2A/PDK4/NMNAT3/ELOVL5/PFKP	41
BP	GO:0016447	somatic recombination of immunoglobulin gene segments	10/2486	52/18670	0.1464	0.3777	0.296	MSH6/POLB/PARP3/TGFB1/EXO1/EXOSC3/BATF/IL2/PTPRC/RNF8	10
BP	GO:0031529	ruffle organization	10/2486	52/18670	0.1464	0.3777	0.296	EPS8/AIF1L/BAG4/TPM1/P2RY12/CCL21/CAV1/MTOR/PFN1/EPS8L1	10
BP	GO:0016482	cytosolic transport	26/2486	158/18670	0.1474	0.38	0.2978	TRAPPC10/VPS53/VPS13C/TBC1D10A/TMEM87A/STX16/STX8/KLHL20/SORL1/PLEKHJ1/DAB2/MSN/AP1AR/MAP2/DENND2A/RAB7B/EMP2/GOSR1/RAB6B/WDR91/TBC1D23/VPS26B/SYS1/HEATR5B/CORO1A/MAGEL2	26
BP	GO:0030183	B cell differentiation	22/2486	131/18670	0.1479	0.3808	0.2985	INPP5D/ITGA4/INHBA/EP300/PPP2R3C/KLF6/GON4L/FCGR2B/LRRC8A/ZBTB7A/BTK/SP3/CYLD/MFNG/MIR17HG/NOTCH2/SFRP1/TLR9/POU2F2/BAK1/PTPRC/DOCK11	22
BP	GO:0046887	positive regulation of hormone secretion	22/2486	131/18670	0.1479	0.3808	0.2985	SRI/INHBA/GHRL/SCT/SERP1/TRH/PFKFB2/CREB1/C2CD2L/EDN3/SPP1/TM7SF3/EGFR/IRS2/C1QTNF1/STX4/PPP3CB/PSMD9/CAPN10/ADCYAP1/NR1H4/ABAT	22
BP	GO:1902850	microtubule cytoskeleton organization involved in mitosis	22/2486	131/18670	0.1479	0.3808	0.2985	SPRY2/PARP3/TACC1/SPRY1/CLASP2/CEP192/TPX2/SPC25/CHMP1B/KIF4A/VCP/RAE1/PLK1/FLNA/NDE1/EML1/TTK/CLASP1/TACC2/SUN2/SETD2/NEK2	22
BP	GO:0060333	interferon-gamma-mediated signaling pathway	16/2486	91/18670	0.1479	0.3809	0.2985	HLA-DPB1/CAMK2G/PPARG/IRF8/ARG1/IRF1/TRIM21/MT2A/PARP9/IRF4/JAK1/PML/HLA-B/MID1/HSP90AB1/HLA-A	16
BP	GO:0035305	negative regulation of dephosphorylation	19/2486	111/18670	0.1488	0.383	0.3002	SPOCD1/SH2D4A/PPP1R15A/BAG4/TNF/TGFB2/PCDH11X/DLG2/CEP192/CCDC8/SEMA4D/PTN/TMEM225/FARP1/FKBP1B/ELL/PCIF1/SET/STYXL1	19
BP	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	12/2486	65/18670	0.1491	0.3833	0.3004	TRA2B/RBM4/MBNL1/WTAP/RBM7/ZBTB7A/CELF1/ZC3H10/KHDRBS1/REST/RBMX/MBNL2	12
BP	GO:0002548	monocyte chemotaxis	12/2486	65/18670	0.1491	0.3833	0.3004	PTPRO/FLT1/CX3CL1/CCL13/CXCL12/TNFRSF11A/CCL21/CCL8/DUSP1/SLIT2/LYN/CCL18	12
BP	GO:0006940	regulation of smooth muscle contraction	12/2486	65/18670	0.1491	0.3833	0.3004	CTTN/GHRL/TACR1/ADRA2A/MIR21/CALCRL/NPNT/KCNMA1/OXTR/CAV1/ITGA2/ABAT	12
BP	GO:0010827	regulation of glucose transmembrane transport	14/2486	78/18670	0.1493	0.3835	0.3006	GRB10/CLIP3/RTN2/PRKCB/TNF/FABP5/IGF1/ADIPOR2/SLC25A27/IRS2/PRKAG2/IL1B/SORBS1/CAPN10	14
BP	GO:0010883	regulation of lipid storage	9/2486	46/18670	0.1508	0.3866	0.303	ITGB3/PPARG/NFKBIA/TNF/LPL/FBXW7/ZC3H12A/MSR1/SIRT1	9
BP	GO:0033628	regulation of cell adhesion mediated by integrin	9/2486	46/18670	0.1508	0.3866	0.303	MUC1/LPXN/TGFB2/CRKL/P2RY12/SFRP2/CCL21/PODXL/LYN	9
BP	GO:0035088	establishment or maintenance of apical/basal cell polarity	9/2486	46/18670	0.1508	0.3866	0.303	SLC9A3R1/PARD3/DLG1/DLG2/MSN/ANK1/FAT1/PDZD11/WNT5A	9
BP	GO:0043277	apoptotic cell clearance	9/2486	46/18670	0.1508	0.3866	0.303	ITGB3/RHOBTB1/PEAR1/C2/GAS6/JMJD6/CD300LF/TREM2/AXL	9
BP	GO:0061245	establishment or maintenance of bipolar cell polarity	9/2486	46/18670	0.1508	0.3866	0.303	SLC9A3R1/PARD3/DLG1/DLG2/MSN/ANK1/FAT1/PDZD11/WNT5A	9
BP	GO:0006626	protein targeting to mitochondrion	17/2486	98/18670	0.1518	0.3888	0.3047	ABLIM3/TIMM23/DNLZ/TOMM20/BAG4/MFF/TIMM44/PINK1/TIMM10/ARIH2/FBXW7/HSP90AA1/SLC25A6/GRPEL1/FZD5/UBE2D3/PDCD5	17
BP	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	17/2486	98/18670	0.1518	0.3888	0.3047	HLA-DPB1/KIF26A/ARF1/DYNC1I1/ACTR10/FCGR2B/TRAF6/KIF4A/AP2A2/SEC24B/KIF2C/CAPZA1/CTSF/DYNLL2/AP1S3/DCTN4/KLC1	17
BP	GO:0007612	learning	24/2486	145/18670	0.1518	0.3888	0.3047	ADCY3/FGF13/CLDN5/EIF2AK4/B4GALT2/JUN/CREB1/CLN8/FOS/YTHDF1/NTRK2/MEIS2/PTN/HRH1/BTG2/PPP3CB/NLGN4X/MTOR/RGS14/ARC/PRKAR2B/EPHB2/SLC6A1/SHANK3	24
BP	GO:0016050	vesicle organization	50/2486	325/18670	0.1527	0.3905	0.3061	TRAPPC10/SCFD1/PEF1/ASIP/ARF1/STX2/CNIH3/LYST/SNCA/SNX19/SQSTM1/CAV2/ARFGEF2/CD59/STX16/STX8/LRMP/CREB1/TGFBRAP1/PLEKHJ1/STXBP1/VPS37A/TFG/CHMP6/GPR143/CHMP1B/FNBP1L/P2RX7/SEC16A/F8/VPS37B/BET1/SEC24B/DNM1/RAB7B/CD34/LAPTM4B/SNAP23/GOSR1/STX4/UVRAG/VAV3/ARFGAP2/CAV1/SAMD9L/RAB8A/UNC13B/STXBP6/CORO1A/PRRT2	50
BP	GO:0002028	regulation of sodium ion transport	15/2486	85/18670	0.1541	0.3905	0.3061	SCN1B/SLC9A3R1/STOM/ARF1/DLG1/ATP1B2/TGFB1/NOS3/P2RX7/HECW2/UTRN/FXYD1/DMD/PER1/NKAIN1	15
BP	GO:0001780	neutrophil homeostasis	4/2486	16/18670	0.1544	0.3905	0.3061	SH2B3/PDE4B/PIK3CD/AXL	4
BP	GO:0002475	antigen processing and presentation via MHC class Ib	4/2486	16/18670	0.1544	0.3905	0.3061	CD1C/CD1B/HLA-B/HLA-A	4
BP	GO:0002739	regulation of cytokine secretion involved in immune response	4/2486	16/18670	0.1544	0.3905	0.3061	TRIM6/TNF/TNFRSF14/WNT5A	4
BP	GO:0007567	parturition	4/2486	16/18670	0.1544	0.3905	0.3061	PLA2G4C/HPGD/PTGFR/OXTR	4
BP	GO:0010566	regulation of ketone biosynthetic process	4/2486	16/18670	0.1544	0.3905	0.3061	PPTC7/BMP2/REST/DKK3	4
BP	GO:0010919	regulation of inositol phosphate biosynthetic process	4/2486	16/18670	0.1544	0.3905	0.3061	SNCA/CD244/PTH1R/HRH1	4
BP	GO:0014048	regulation of glutamate secretion	4/2486	16/18670	0.1544	0.3905	0.3061	SNCA/TRH/STXBP1/P2RX7	4
BP	GO:0022038	corpus callosum development	4/2486	16/18670	0.1544	0.3905	0.3061	RTN4RL1/NIN/TSKU/EPHB2	4
BP	GO:0032305	positive regulation of icosanoid secretion	4/2486	16/18670	0.1544	0.3905	0.3061	CYP4F2/P2RX7/TNFRSF11A/IL1B	4
BP	GO:0032604	granulocyte macrophage colony-stimulating factor production	4/2486	16/18670	0.1544	0.3905	0.3061	IL23R/IL1B/IL17D/TLR9	4
BP	GO:0034116	positive regulation of heterotypic cell-cell adhesion	4/2486	16/18670	0.1544	0.3905	0.3061	TNF/CEACAM6/IL1B/THY1	4
BP	GO:0034975	protein folding in endoplasmic reticulum	4/2486	16/18670	0.1544	0.3905	0.3061	HSP90B1/PDIA3/DNAJC10/HSPA5	4
BP	GO:0035372	protein localization to microtubule	4/2486	16/18670	0.1544	0.3905	0.3061	DIAPH1/CRIPT/TTBK2/MID1	4
BP	GO:0042033	chemokine biosynthetic process	4/2486	16/18670	0.1544	0.3905	0.3061	TNF/ELANE/IL1B/WNT5A	4
BP	GO:0042447	hormone catabolic process	4/2486	16/18670	0.1544	0.3905	0.3061	ACE/SPP1/IDE/DIO2	4
BP	GO:0043031	negative regulation of macrophage activation	4/2486	16/18670	0.1544	0.3905	0.3061	FCGR2B/CX3CL1/ZC3H12A/PTPRC	4
BP	GO:0048820	hair follicle maturation	4/2486	16/18670	0.1544	0.3905	0.3061	TGFB2/NOM1/NSUN2/WNT5A	4
BP	GO:0050755	chemokine metabolic process	4/2486	16/18670	0.1544	0.3905	0.3061	TNF/ELANE/IL1B/WNT5A	4
BP	GO:0070293	renal absorption	4/2486	16/18670	0.1544	0.3905	0.3061	HBB/SLC9A3R1/GAS6/HAS2	4
BP	GO:0070863	positive regulation of protein exit from endoplasmic reticulum	4/2486	16/18670	0.1544	0.3905	0.3061	EDEM1/SORL1/SEC16A/SLC35D3	4
BP	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade	4/2486	16/18670	0.1544	0.3905	0.3061	TNF/SPPL3/LMCD1/IGF1	4
BP	GO:0071871	response to epinephrine	4/2486	16/18670	0.1544	0.3905	0.3061	SIRT2/SNCA/PDE4B/RYR2	4
BP	GO:0090153	regulation of sphingolipid biosynthetic process	4/2486	16/18670	0.1544	0.3905	0.3061	ORMDL1/TNF/SMPD3/ORMDL2	4
BP	GO:0106058	positive regulation of calcineurin-mediated signaling	4/2486	16/18670	0.1544	0.3905	0.3061	TNF/SPPL3/LMCD1/IGF1	4
BP	GO:1900451	positive regulation of glutamate receptor signaling pathway	4/2486	16/18670	0.1544	0.3905	0.3061	PINK1/ARC/EPHB2/SHANK3	4
BP	GO:1903830	magnesium ion transmembrane transport	4/2486	16/18670	0.1544	0.3905	0.3061	CNNM4/MMGT1/NIPAL2/TUSC3	4
BP	GO:1905038	regulation of membrane lipid metabolic process	4/2486	16/18670	0.1544	0.3905	0.3061	ORMDL1/TNF/SMPD3/ORMDL2	4
BP	GO:2000303	regulation of ceramide biosynthetic process	4/2486	16/18670	0.1544	0.3905	0.3061	ORMDL1/TNF/SMPD3/ORMDL2	4
BP	GO:0061077	chaperone-mediated protein folding	11/2486	59/18670	0.1546	0.3906	0.3061	CLU/FKBP4/PPID/DNAJB14/HSPB1/DNAJC24/FKBP1B/HSPB6/PDCD5/HSPA5/HSPA9	11
BP	GO:2000756	regulation of peptidyl-lysine acetylation	11/2486	59/18670	0.1546	0.3906	0.3061	MUC1/SNCA/TWIST1/TGFB1/FLCN/SIRT1/SETD5/IL1B/SET/RPS6KA5/SIN3A	11
BP	GO:0001709	cell fate determination	8/2486	40/18670	0.1548	0.3906	0.3061	HES1/CYP26B1/PRRX1/KLF4/MCL1/TBX2/NOTCH2/EBF2	8
BP	GO:0050832	defense response to fungus	8/2486	40/18670	0.1548	0.3906	0.3061	CTSG/ARG1/LTF/TGFB1/ELANE/JAGN1/RARRES2/COTL1	8
BP	GO:0071548	response to dexamethasone	8/2486	40/18670	0.1548	0.3906	0.3061	ARG1/TGFB1/EGFR/ASS1/AQP1/CPS1/NR3C1/FIBIN	8
BP	GO:0072210	metanephric nephron development	8/2486	40/18670	0.1548	0.3906	0.3061	IRX2/HES1/PDGFRA/SMO/PDGFRB/SOX9/CD34/SIX2	8
BP	GO:0051881	regulation of mitochondrial membrane potential	13/2486	72/18670	0.1553	0.3915	0.3068	PMAIP1/PPP2R3C/SLC25A33/PINK1/PYCR1/BCL2L1/P2RX7/VCP/SLC25A27/IFI6/DCN/BAK1/KDR	13
BP	GO:1903051	negative regulation of proteolysis involved in cellular protein catabolic process	13/2486	72/18670	0.1553	0.3915	0.3068	GABARAPL2/UBXN1/SMARCC1/USP7/PML/WAC/MTM1/CAMLG/UBE2G2/HSP90AB1/RPS7/TAF1/GIPC1	13
BP	GO:0042552	myelination	22/2486	132/18670	0.1563	0.3938	0.3087	CLU/SIRT2/MBP/MPP5/WASF3/PARD3/CD9/DLG1/TGFB1/MALL/NTRK2/PTN/LGI4/TMEM98/ZNF24/GPC1/ANK2/SH3TC2/MTOR/BCAS1/KIF14/EIF2B2	22
BP	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	22/2486	132/18670	0.1563	0.3938	0.3087	PMAIP1/CRADD/FADD/PPARG/CASP4/RPS27L/SNCA/TNF/BCL10/SIRT1/PML/MAP3K5/VCP/PRR7/DIABLO/NLRP1/REST/PPM1F/DLC1/BAK1/PDCD5/ANP32B	22
BP	GO:0001659	temperature homeostasis	28/2486	173/18670	0.1575	0.3952	0.3098	GRB10/EDNRB/APC/TNF/FABP5/GHRL/LCN2/KDM6B/FLCN/IGF1R/IRF4/GPR3/DDIT3/ADIPOR2/HOXC10/ACOT13/TNFRSF11A/MFAP2/BSCL2/NOTCH1/DIO2/IL1B/ZNF423/OXTR/EBF2/CAV1/ADCYAP1/ABAT	28
BP	GO:0055002	striated muscle cell development	28/2486	173/18670	0.1575	0.3952	0.3098	TMOD1/YY1/CACNA2D2/CAV2/TPM1/AKAP13/SGCD/LOX/UCHL1/OBSL1/LDB3/IGF1/SIX1/PDGFRA/LMOD1/ALPK3/SMO/PDGFRB/SHOX2/FLNC/CSRP2/SGCB/ALPK2/MTOR/MYH10/DMD/CSRP1/PIN1	28
BP	GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	28/2486	173/18670	0.1575	0.3952	0.3098	MMP8/TNF/TGFB2/TRAF4/FCGR2B/ERN1/ZC3H12A/BMP2/TRAF6/MAP3K2/SAMD5/MAP3K5/TPD52L1/PLCB1/TNFRSF11A/FZD10/MID1/IL1B/CCL21/FZD5/PDCD10/WNT5A/TLR9/IL26/MAP3K3/LYN/FZD4/RASSF2	28
BP	GO:0018196	peptidyl-asparagine modification	7/2486	34/18670	0.1581	0.3952	0.3098	VCP/DDOST/MGAT2/STT3B/UBE2G2/ST6GAL1/TUSC3	7
BP	GO:0043368	positive T cell selection	7/2486	34/18670	0.1581	0.3952	0.3098	IRF4/IL23R/CYLD/BATF/MTOR/SPN/PTPRC	7
BP	GO:0070670	response to interleukin-4	7/2486	34/18670	0.1581	0.3952	0.3098	KEAP1/ARG1/PML/CD300LF/HSP90AB1/HSPA5/CORO1A	7
BP	GO:0070884	regulation of calcineurin-NFAT signaling cascade	7/2486	34/18670	0.1581	0.3952	0.3098	FHL2/TNF/SPPL3/LMCD1/RCAN2/IGF1/MTOR	7
BP	GO:0097009	energy homeostasis	7/2486	34/18670	0.1581	0.3952	0.3098	FLCN/IRX3/NR1D2/AMPD2/BMP8A/SLC35D3/MRAP2	7
BP	GO:0106056	regulation of calcineurin-mediated signaling	7/2486	34/18670	0.1581	0.3952	0.3098	FHL2/TNF/SPPL3/LMCD1/RCAN2/IGF1/MTOR	7
BP	GO:0014902	myotube differentiation	19/2486	112/18670	0.1581	0.3952	0.3098	BDNF/CD9/CAV2/TMEM119/BHLHE41/PTGFRN/CYP26B1/EHD2/IGF1/SIX1/CDON/SMO/KLF5/NOTCH1/SHOX2/MYH9/TBX1/FER1L5/MTOR	19
BP	GO:1904894	positive regulation of STAT cascade	16/2486	92/18670	0.1582	0.3952	0.3098	TNF/HES1/CRLF1/PARP9/IL23R/IGF1/IL12A/IL2/NOTCH1/CRLF3/IL26/CD300A/HCLS1/IL10RA/LYN/GHR	16
BP	GO:2000117	negative regulation of cysteine-type endopeptidase activity	16/2486	92/18670	0.1582	0.3952	0.3098	SNCA/LTF/NOL3/IFI16/HERPUD1/GAS6/RAF1/SFRP2/MMP9/WNT9A/AQP1/KLF4/SERPINB9/IFI6/TRIAP1/CRYAB	16
BP	GO:0043534	blood vessel endothelial cell migration	29/2486	180/18670	0.1586	0.3952	0.3098	PDPK1/PPARG/VEGFC/TGFB1/NRP1/FBXW7/FGF18/MMRN2/SIRT1/JUP/NOS3/HSPB1/CARD10/VASH1/EPHB4/RHOJ/SRPX2/EFNB2/MEOX2/KLF4/EMP2/NOTCH1/CLEC14A/MYH9/ANGPT2/PDCD10/MAP3K3/SLIT2/KDR	29
BP	GO:0052548	regulation of endopeptidase activity	64/2486	425/18670	0.159	0.3952	0.3098	PROS1/SLPI/PSMD14/PMAIP1/CRADD/MBP/FADD/PPARG/TBC1D10A/CASP4/RPS27L/SNCA/TNF/CD109/BCL10/LTF/NOL3/SORL1/IFI16/HERPUD1/GAS6/MIR21/RAF1/SIRT1/SERPING1/ASPH/SFRP2/SERPINH1/PML/WFDC1/MAP3K5/VCP/TFPI/PRR7/MMP9/WNT9A/TIMP3/AQP1/KLF4/SERPINB9/WFDC3/IFI6/SERPINA3/DIABLO/TIMP4/NLRP1/REST/PPM1F/LYN/ITIH2/DLC1/TRIAP1/BAK1/PDCD5/PSME1/A2M/ANP32B/SPINT2/MGMT/CRYAB/LXN/RARRES1/NLRP7/CIDEB	64
BP	GO:0001759	organ induction	5/2486	22/18670	0.1597	0.3952	0.3098	SPRY1/BMP2/SIX1/FRS2/HOXA11	5
BP	GO:0002052	positive regulation of neuroblast proliferation	5/2486	22/18670	0.1597	0.3952	0.3098	VEGFC/CX3CL1/SMO/NOTCH1/GLI3	5
BP	GO:0006783	heme biosynthetic process	5/2486	22/18670	0.1597	0.3952	0.3098	ALAS2/UROD/FXN/IREB2/ALAS1	5
BP	GO:0019883	antigen processing and presentation of endogenous antigen	5/2486	22/18670	0.1597	0.3952	0.3098	CD1C/CD1B/HLA-B/IDE/HLA-A	5
BP	GO:0021801	cerebral cortex radial glia guided migration	5/2486	22/18670	0.1597	0.3952	0.3098	P2RY12/GLI3/LAMB1/CDK5R1/SUN2	5
BP	GO:0022030	telencephalon glial cell migration	5/2486	22/18670	0.1597	0.3952	0.3098	P2RY12/GLI3/LAMB1/CDK5R1/SUN2	5
BP	GO:0030878	thyroid gland development	5/2486	22/18670	0.1597	0.3952	0.3098	RAF1/THRB/SIX1/TBX1/HOXA3	5
BP	GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane	5/2486	22/18670	0.1597	0.3952	0.3098	STX2/STXBP1/SNAP23/STX4/PRRT2	5
BP	GO:0032469	endoplasmic reticulum calcium ion homeostasis	5/2486	22/18670	0.1597	0.3952	0.3098	ITPR1/HERPUD1/PML/BAK1/WFS1	5
BP	GO:0035024	negative regulation of Rho protein signal transduction	5/2486	22/18670	0.1597	0.3952	0.3098	SCAI/FLCN/ITGA3/DLC1/TNFAIP1	5
BP	GO:0035929	steroid hormone secretion	5/2486	22/18670	0.1597	0.3952	0.3098	INHBA/GHRL/AGTR1/C1QTNF1/FZD4	5
BP	GO:0044342	type B pancreatic cell proliferation	5/2486	22/18670	0.1597	0.3952	0.3098	IGFBP4/IGFBP5/NUPR1/SFRP1/IGFBP3	5
BP	GO:0046058	cAMP metabolic process	5/2486	22/18670	0.1597	0.3952	0.3098	ADCY3/ADCY7/ADCY4/PDE4B/ADCY6	5
BP	GO:0050765	negative regulation of phagocytosis	5/2486	22/18670	0.1597	0.3952	0.3098	TGFB1/FCGR2B/CD300LF/CD300A/SYT11	5
BP	GO:0051457	maintenance of protein location in nucleus	5/2486	22/18670	0.1597	0.3952	0.3098	PML/TAF3/RANGAP1/BARD1/SUN2	5
BP	GO:0060487	lung epithelial cell differentiation	5/2486	22/18670	0.1597	0.3952	0.3098	CREB1/THRB/NFIB/SOX9/YAP1	5
BP	GO:0090312	positive regulation of protein deacetylation	5/2486	22/18670	0.1597	0.3952	0.3098	AKAP8L/NIPBL/TGFB1/PINK1/AKAP8	5
BP	GO:0097320	plasma membrane tubulation	5/2486	22/18670	0.1597	0.3952	0.3098	PACSIN1/EHD2/FNBP1L/WHAMM/FCHO1	5
BP	GO:1901984	negative regulation of protein acetylation	5/2486	22/18670	0.1597	0.3952	0.3098	SNCA/TWIST1/SIRT1/SET/SIN3A	5
BP	GO:1904892	regulation of STAT cascade	24/2486	146/18670	0.16	0.3952	0.3098	SH2B3/TNF/PPP2CA/HES1/CRLF1/PARP9/IL23R/IGF1/EGF/IL12A/IL2/NOTCH1/CRLF3/CDK5R1/IL26/CD300A/CNOT7/CAV1/HCLS1/INPP5F/IL10RA/LYN/GHR/PTPRC	24
BP	GO:0001773	myeloid dendritic cell activation	6/2486	28/18670	0.1601	0.3952	0.3098	TGFB1/BATF2/IRF4/TRAF6/BATF/BATF3	6
BP	GO:0008045	motor neuron axon guidance	6/2486	28/18670	0.1601	0.3952	0.3098	PLXNA3/NRP1/CHN1/SLIT2/SLIT1/MYCBP2	6
BP	GO:0010894	negative regulation of steroid biosynthetic process	6/2486	28/18670	0.1601	0.3952	0.3098	ERLIN1/BMP2/ERLIN2/REST/DKK3/NR1H4	6
BP	GO:0033598	mammary gland epithelial cell proliferation	6/2486	28/18670	0.1601	0.3952	0.3098	IQGAP3/PHB2/CCND1/RREB1/WNT5A/MST1	6
BP	GO:0033688	regulation of osteoblast proliferation	6/2486	28/18670	0.1601	0.3952	0.3098	GATA1/TMEM119/LTF/BMP2/CTHRC1/SFRP1	6
BP	GO:0034368	protein-lipid complex remodeling	6/2486	28/18670	0.1601	0.3952	0.3098	LPL/APOC1/GPIHBP1/AGTR1/PLA2G2A/PLTP	6
BP	GO:0034369	plasma lipoprotein particle remodeling	6/2486	28/18670	0.1601	0.3952	0.3098	LPL/APOC1/GPIHBP1/AGTR1/PLA2G2A/PLTP	6
BP	GO:0035456	response to interferon-beta	6/2486	28/18670	0.1601	0.3952	0.3098	TRIM6/IRF1/IFITM3/IFI16/IFITM2/UBE2G2	6
BP	GO:0042634	regulation of hair cycle	6/2486	28/18670	0.1601	0.3952	0.3098	NIPBL/TNF/TGFB2/SMO/WNT5A/PER1	6
BP	GO:1902003	regulation of amyloid-beta formation	6/2486	28/18670	0.1601	0.3952	0.3098	CLU/TNF/SORL1/IGF1/SPON1/PIN1	6
BP	GO:1902932	positive regulation of alcohol biosynthetic process	6/2486	28/18670	0.1601	0.3952	0.3098	SNCA/TNF/CD244/PTH1R/HRH1/IL1B	6
BP	GO:1903792	negative regulation of anion transport	6/2486	28/18670	0.1601	0.3952	0.3098	CYP4F2/TRH/IRS2/SFRP4/MTOR/ABAT	6
BP	GO:0000186	activation of MAPKK activity	10/2486	53/18670	0.1602	0.3952	0.3098	CRKL/MAP3K14/RAF1/MAP3K2/EGFR/MAP3K5/MAP3K1/EGF/FRS2/MAP3K3	10
BP	GO:0021879	forebrain neuron differentiation	10/2486	53/18670	0.1602	0.3952	0.3098	INHBA/LHX6/PLXNA3/HES1/NRP1/SATB2/WNT5A/SLIT2/SHANK3/LHX8	10
BP	GO:0031638	zymogen activation	10/2486	53/18670	0.1602	0.3952	0.3098	FADD/TBC1D10A/IFI16/ASPH/C1RL/PLAT/C1R/BAK1/CLEC3B/CIDEB	10
BP	GO:0032964	collagen biosynthetic process	10/2486	53/18670	0.1602	0.3952	0.3098	PPARG/ARG1/TGFB1/CYGB/SERPINH1/PDGFRB/COL5A1/CREB3L1/ITGA2/LARP6	10
BP	GO:0060563	neuroepithelial cell differentiation	10/2486	53/18670	0.1602	0.3952	0.3098	SLC9A3R1/MCOLN3/B9D1/HES1/JAG2/BMP2/SEC24B/NOTCH1/DLX3/TMEM231	10
BP	GO:0071320	cellular response to cAMP	10/2486	53/18670	0.1602	0.3952	0.3098	PDE2A/RAPGEF3/STC1/ASS1/IGFBP5/SLC26A6/AQP1/CPS1/NOX4/HSPA5	10
BP	GO:1905517	macrophage migration	10/2486	53/18670	0.1602	0.3952	0.3098	EDNRB/CSF1/CD9/AKIRIN1/CX3CL1/P2RY12/RARRES2/MTUS1/TREM2/MST1	10
BP	GO:0031110	regulation of microtubule polymerization or depolymerization	14/2486	79/18670	0.1605	0.3957	0.3102	FGF13/NAV3/CLIP3/APC/SNCA/FKBP4/CLASP2/NIN/MAP2/TTBK2/MID1/CDK5R1/CDH5/CLASP1	14
BP	GO:1905207	regulation of cardiocyte differentiation	12/2486	66/18670	0.1615	0.398	0.3119	YY1/TBX5/TGFB2/TGFB1/BMP2/EGFR/IGF1/EFNB2/FRS2/MTOR/SOX6/PIN1	12
BP	GO:0062013	positive regulation of small molecule metabolic process	25/2486	153/18670	0.1615	0.398	0.3119	PMAIP1/PPARG/SNCA/TNF/TWIST1/CD244/PINK1/PFKFB2/WDR5/SIRT1/NOS3/P2RX7/IGF1/EGF/VCP/PTH1R/IRS2/HRH1/HAS2/NUPR1/IL1B/SORBS1/TREM2/NR1H4/ELOVL5	25
BP	GO:0007623	circadian rhythm	33/2486	208/18670	0.1617	0.3981	0.312	RBM4/JUND/PPARG/EP300/BHLHE41/JUN/GHRL/SFPQ/ARNTL2/BHLHE40/CREB1/FBXW7/KDM2A/USP7/SIRT1/EGFR/NTRK2/PML/MTA1/ASS1/GPR176/TNFRSF11A/KLF10/HS3ST2/NR1D2/NR2F6/NCOA2/NONO/MTOR/MYCBP2/PER1/SIN3A/MAGEL2	33
BP	GO:0050670	regulation of lymphocyte proliferation	33/2486	208/18670	0.1617	0.3981	0.312	INPP5D/HLA-DPB1/ARG2/FADD/ARG1/IRF1/DLG1/TGFB1/IGFBP2/CD276/HES1/FCGR2B/TWSG1/MIR21/BTK/TRAF6/IL23R/IGF1/IRS2/PDCD1LG2/IL12A/IL2/TNFRSF14/IL1B/GPNMB/VAV3/TLR9/CD300A/LYN/SPN/RC3H1/PTPRC/CORO1A	33
BP	GO:0007052	mitotic spindle organization	18/2486	106/18670	0.165	0.4055	0.3178	PARP3/TACC1/CLASP2/CEP192/TPX2/SPC25/CHMP1B/KIF4A/VCP/RAE1/PLK1/FLNA/EML1/TTK/CLASP1/TACC2/SUN2/NEK2	18
BP	GO:0051963	regulation of synapse assembly	18/2486	106/18670	0.165	0.4055	0.3178	BDNF/SNCA/GHRL/CUX2/AGRN/GPC4/TPBG/NTRK2/LRRN1/SEMA4D/SIX1/FLRT2/SRPX2/GAP43/OXTR/WNT5A/SLIT1/EPHB2	18
BP	GO:0001942	hair follicle development	15/2486	86/18670	0.165	0.4055	0.3178	INHBA/TNF/CD109/TGFB2/LDB1/NOM1/EGFR/RELA/IGFBP5/SMO/SOX9/NOTCH1/NSUN2/WNT5A/INTU	15
BP	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	15/2486	86/18670	0.165	0.4055	0.3178	PMAIP1/CRADD/FADD/PPARG/CASP4/RPS27L/SNCA/TNF/PML/VCP/DIABLO/NLRP1/DLC1/BAK1/ANP32B	15
BP	GO:0031023	microtubule organizing center organization	22/2486	133/18670	0.1651	0.4055	0.3178	RBM14/PARD6G/CLASP2/CEP192/CHMP1B/MDM1/CEP135/HAUS8/ODF2/NIN/PLK1/C2CD3/UVRAG/USP33/HAUS2/NDE1/PARD6A/CLASP1/TMEM67/HEPACAM2/PARD6B/NEK2	22
BP	GO:0002204	somatic recombination of immunoglobulin genes involved in immune response	9/2486	47/18670	0.1658	0.4064	0.3185	MSH6/PARP3/TGFB1/EXO1/EXOSC3/BATF/IL2/PTPRC/RNF8	9
BP	GO:0002208	somatic diversification of immunoglobulins involved in immune response	9/2486	47/18670	0.1658	0.4064	0.3185	MSH6/PARP3/TGFB1/EXO1/EXOSC3/BATF/IL2/PTPRC/RNF8	9
BP	GO:0031952	regulation of protein autophosphorylation	9/2486	47/18670	0.1658	0.4064	0.3185	JUN/VEGFC/ACE/PPP2R5E/GPNMB/CAV1/TNKS1BP1/PTPRC/RASSF2	9
BP	GO:0045058	T cell selection	9/2486	47/18670	0.1658	0.4064	0.3185	JAG2/IRF4/IL23R/CYLD/BATF/GLI3/MTOR/SPN/PTPRC	9
BP	GO:0045190	isotype switching	9/2486	47/18670	0.1658	0.4064	0.3185	MSH6/PARP3/TGFB1/EXO1/EXOSC3/BATF/IL2/PTPRC/RNF8	9
BP	GO:0050435	amyloid-beta metabolic process	9/2486	47/18670	0.1658	0.4064	0.3185	CLU/MME/TNF/SORL1/ACE/IGF1/IDE/SPON1/PIN1	9
BP	GO:0000281	mitotic cytokinesis	13/2486	73/18670	0.1673	0.4095	0.321	CIT/RTKN/ARF1/APC/UNC119/ANLN/CHMP6/CHMP1B/KIF4A/PLK1/KIF20A/MYH10/LZTS2	13
BP	GO:0031100	animal organ regeneration	13/2486	73/18670	0.1673	0.4095	0.321	ANXA3/PPARG/TGFB1/GAS6/CCND1/EGFR/NNMT/CXCL12/NOTCH1/GLI3/ANGPT2/BAK1/AXL	13
BP	GO:1903524	positive regulation of blood circulation	13/2486	73/18670	0.1673	0.4095	0.321	GHRL/TGFB2/TPM1/GJA5/MIR21/EDN3/GCH1/EGFR/SLC1A1/HRH1/OXTR/RYR2/CAV1	13
BP	GO:0072524	pyridine-containing compound metabolic process	31/2486	195/18670	0.1676	0.4101	0.3215	ME1/SLC4A1/NUP93/PFKFB2/DHTKD1/PARP9/ZBTB7A/NUP50/NNMT/QPRT/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/VCP/RAE1/NUP188/NUP160/NUP54/NADSYN1/NUP214/NUP155/FOXK2/NUPR1/SLC2A6/PRKAG2/AOX1/NMNAT3/RPIA/PFKP	31
BP	GO:0046620	regulation of organ growth	19/2486	113/18670	0.1677	0.4102	0.3215	YY1/MAPK11/TBX5/CACNA2D2/FXN/SERP1/FOXC1/HLX/IGF1/MIR17HG/STK4/SMO/TBX2/NOTCH1/YAP1/JARID2/ZFPM2/MTOR/PIN1	19
BP	GO:0043966	histone H3 acetylation	11/2486	60/18670	0.168	0.4106	0.3218	POLE3/TAF10/YEATS2/LDB1/WDR5/IRF4/SIRT1/MCM3AP/PER1/SIN3A/ING5	11
BP	GO:0045576	mast cell activation	11/2486	60/18670	0.168	0.4106	0.3218	PDPK1/STXBP1/BTK/C12orf4/CBL/PIK3CD/IL13RA2/SNAP23/CD300LF/CD300A/LYN	11
BP	GO:0061025	membrane fusion	25/2486	154/18670	0.1698	0.4124	0.3232	STX2/CD9/SNCA/CAV2/STX16/STX8/LRMP/GAS6/TGFBRAP1/STXBP1/BET1/RAB7B/TIE1/SNAP23/GOSR1/STX4/UVRAG/VAV3/BNIP1/SAMD9L/RAB8A/STXBP6/CORO1A/PRRT2/NAPG	25
BP	GO:0006721	terpenoid metabolic process	20/2486	120/18670	0.1701	0.4124	0.3232	DHRS9/LPL/AGRN/CYP26B1/ABCA4/SDC2/GPC4/EGFR/RARRES2/GPIHBP1/GPC6/CRABP1/CYP27C1/ALDH1A3/ALDH1A2/GPC1/HMGCS1/CYP3A5/RBP1/ADH1C	20
BP	GO:0050434	positive regulation of viral transcription	8/2486	41/18670	0.1713	0.4124	0.3232	EP300/JUN/DHX9/CDK9/CHD1/POLR2G/RSF1/POLR2D	8
BP	GO:0000727	double-strand break repair via break-induced replication	3/2486	11/18670	0.1719	0.4124	0.3232	CDC45/MUS81/MCM5	3
BP	GO:0002328	pro-B cell differentiation	3/2486	11/18670	0.1719	0.4124	0.3232	HES1/FLCN/NOTCH1	3
BP	GO:0002887	negative regulation of myeloid leukocyte mediated immunity	3/2486	11/18670	0.1719	0.4124	0.3232	FCGR2B/IL13RA2/CD300A	3
BP	GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	3/2486	11/18670	0.1719	0.4124	0.3232	TNF/FCGR2B/PTPRC	3
BP	GO:0006620	posttranslational protein targeting to endoplasmic reticulum membrane	3/2486	11/18670	0.1719	0.4124	0.3232	SEC62/SEC61B/HSPA5	3
BP	GO:0006857	oligopeptide transport	3/2486	11/18670	0.1719	0.4124	0.3232	SLC15A4/SLC9A3R1/SLC26A6	3
BP	GO:0016264	gap junction assembly	3/2486	11/18670	0.1719	0.4124	0.3232	ACE/GJA5/CAV1	3
BP	GO:0019532	oxalate transport	3/2486	11/18670	0.1719	0.4124	0.3232	SLC26A10/SLC26A6/SLC26A8	3
BP	GO:0032060	bleb assembly	3/2486	11/18670	0.1719	0.4124	0.3232	ANLN/P2RX7/EMP2	3
BP	GO:0032306	regulation of prostaglandin secretion	3/2486	11/18670	0.1719	0.4124	0.3232	P2RX7/TNFRSF11A/IL1B	3
BP	GO:0032351	negative regulation of hormone metabolic process	3/2486	11/18670	0.1719	0.4124	0.3232	BMP2/REST/DKK3	3
BP	GO:0034115	negative regulation of heterotypic cell-cell adhesion	3/2486	11/18670	0.1719	0.4124	0.3232	MBP/MYADM/KLF4	3
BP	GO:0035457	cellular response to interferon-alpha	3/2486	11/18670	0.1719	0.4124	0.3232	GAS6/IFIT3/AXL	3
BP	GO:0035542	regulation of SNARE complex assembly	3/2486	11/18670	0.1719	0.4124	0.3232	STXBP1/STXBP6/PRRT2	3
BP	GO:0039532	negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway	3/2486	11/18670	0.1719	0.4124	0.3232	GPATCH3/TSPAN6/RNF125	3
BP	GO:0042023	DNA endoreduplication	3/2486	11/18670	0.1719	0.4124	0.3232	MSH6/FBXW7/E2F8	3
BP	GO:0043117	positive regulation of vascular permeability	3/2486	11/18670	0.1719	0.4124	0.3232	TGFB1/PTP4A3/PDE2A	3
BP	GO:0045217	cell-cell junction maintenance	3/2486	11/18670	0.1719	0.4124	0.3232	CD177/PLEKHA7/PARD6A	3
BP	GO:0046007	negative regulation of activated T cell proliferation	3/2486	11/18670	0.1719	0.4124	0.3232	ARG1/PDCD1LG2/RC3H1	3
BP	GO:0048672	positive regulation of collateral sprouting	3/2486	11/18670	0.1719	0.4124	0.3232	BDNF/RND2/SEMA4D	3
BP	GO:0048853	forebrain morphogenesis	3/2486	11/18670	0.1719	0.4124	0.3232	SMO/WNT5A/SLIT1	3
BP	GO:0051024	positive regulation of immunoglobulin secretion	3/2486	11/18670	0.1719	0.4124	0.3232	IL2/STX4/IL33	3
BP	GO:0060272	embryonic skeletal joint morphogenesis	3/2486	11/18670	0.1719	0.4124	0.3232	SHOX2/HOXA11/HYAL1	3
BP	GO:0060379	cardiac muscle cell myoblast differentiation	3/2486	11/18670	0.1719	0.4124	0.3232	TBX2/NOTCH1/REST	3
BP	GO:0060525	prostate glandular acinus development	3/2486	11/18670	0.1719	0.4124	0.3232	FRS2/NOTCH1/SFRP1	3
BP	GO:0060837	blood vessel endothelial cell differentiation	3/2486	11/18670	0.1719	0.4124	0.3232	NRP1/NOTCH1/FOXJ2	3
BP	GO:0060992	response to fungicide	3/2486	11/18670	0.1719	0.4124	0.3232	KDM6B/BCL2L1/KLF4	3
BP	GO:0061314	Notch signaling involved in heart development	3/2486	11/18670	0.1719	0.4124	0.3232	HEYL/NOTCH1/NOTCH2	3
BP	GO:0070471	uterine smooth muscle contraction	3/2486	11/18670	0.1719	0.4124	0.3232	TACR1/OXTR/ABAT	3
BP	GO:0070587	regulation of cell-cell adhesion involved in gastrulation	3/2486	11/18670	0.1719	0.4124	0.3232	MBP/MYADM/KLF4	3
BP	GO:0070933	histone H4 deacetylation	3/2486	11/18670	0.1719	0.4124	0.3232	SIRT2/REST/SIRT7	3
BP	GO:0071372	cellular response to follicle-stimulating hormone stimulus	3/2486	11/18670	0.1719	0.4124	0.3232	INHBA/NOTCH1/HMGCS1	3
BP	GO:0072321	chaperone-mediated protein transport	3/2486	11/18670	0.1719	0.4124	0.3232	CLU/CLIP3/TIMM10	3
BP	GO:0072683	T cell extravasation	3/2486	11/18670	0.1719	0.4124	0.3232	FADD/CRKL/XG	3
BP	GO:0090042	tubulin deacetylation	3/2486	11/18670	0.1719	0.4124	0.3232	SIRT2/BEX4/EP300	3
BP	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	3/2486	11/18670	0.1719	0.4124	0.3232	ITGB3/EFNB2/ARC	3
BP	GO:1901096	regulation of autophagosome maturation	3/2486	11/18670	0.1719	0.4124	0.3232	SMCR8/FYCO1/UVRAG	3
BP	GO:1901678	iron coordination entity transport	3/2486	11/18670	0.1719	0.4124	0.3232	LCN2/ABCB6/ABCB7	3
BP	GO:1902563	regulation of neutrophil activation	3/2486	11/18670	0.1719	0.4124	0.3232	CD177/FCGR2B/CD300A	3
BP	GO:1903011	negative regulation of bone development	3/2486	11/18670	0.1719	0.4124	0.3232	LTF/FBXW7/FBN1	3
BP	GO:1904995	negative regulation of leukocyte adhesion to vascular endothelial cell	3/2486	11/18670	0.1719	0.4124	0.3232	CXCL12/KLF4/CCL21	3
BP	GO:1905245	regulation of aspartic-type peptidase activity	3/2486	11/18670	0.1719	0.4124	0.3232	SORL1/LYN/NLRP7	3
BP	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	3/2486	11/18670	0.1719	0.4124	0.3232	DDIT3/CREB3L1/HSPA5	3
BP	GO:2000318	positive regulation of T-helper 17 type immune response	3/2486	11/18670	0.1719	0.4124	0.3232	MIR21/NFKBIZ/IL23R	3
BP	GO:2000767	positive regulation of cytoplasmic translation	3/2486	11/18670	0.1719	0.4124	0.3232	YTHDF2/DHX9/MTOR	3
BP	GO:0043462	regulation of ATPase activity	14/2486	80/18670	0.1722	0.4127	0.3234	GABARAPL2/MYL4/LTF/DNAJA1/ATP1B2/DHX9/TPM1/DNAJC10/DNAJC24/TLR9/RYR2/DNAJA2/DYNLL2/PFN1	14
BP	GO:0035270	endocrine system development	21/2486	127/18670	0.1722	0.4127	0.3234	PDPK1/PBX1/CRKL/CREB1/HES1/CDKN1C/RAF1/THRB/BMP2/SIX1/PDGFRA/SMO/SOX9/ALDH1A2/WNT5A/MSX1/TBX1/BAK1/ADCYAP1/DKK3/HOXA3	21
BP	GO:0035282	segmentation	17/2486	100/18670	0.1722	0.4127	0.3234	IRX2/EP300/MEOX1/NRP1/PCSK6/FOXC1/IRX3/SFRP2/HOXD8/FRS2/MEOX2/NOTCH1/SFRP1/ALDH1A2/FZD5/WNT5A/PALB2	17
BP	GO:0009166	nucleotide catabolic process	29/2486	182/18670	0.1738	0.4158	0.3259	NUDT15/SLC4A1/NUP93/TDG/PFKFB2/PDE2A/SAMHD1/DHTKD1/ZBTB7A/PDE4B/NUP50/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/VCP/RAE1/NUP188/NUP160/NUP54/NUP214/NUP155/FOXK2/NUPR1/SLC2A6/PRKAG2/PDE1A/PFKP	29
BP	GO:0002920	regulation of humoral immune response	22/2486	134/18670	0.1741	0.4158	0.3259	CLU/PROS1/C1QB/C1QA/C1QC/CR1L/CFH/PPP2R3C/TNF/CD59/C2/CFB/FCGR2B/SERPING1/CFHR2/CPN1/C1R/IL1B/C1S/CFI/A2M/PTPRC	22
BP	GO:0007272	ensheathment of neurons	22/2486	134/18670	0.1741	0.4158	0.3259	CLU/SIRT2/MBP/MPP5/WASF3/PARD3/CD9/DLG1/TGFB1/MALL/NTRK2/PTN/LGI4/TMEM98/ZNF24/GPC1/ANK2/SH3TC2/MTOR/BCAS1/KIF14/EIF2B2	22
BP	GO:0008366	axon ensheathment	22/2486	134/18670	0.1741	0.4158	0.3259	CLU/SIRT2/MBP/MPP5/WASF3/PARD3/CD9/DLG1/TGFB1/MALL/NTRK2/PTN/LGI4/TMEM98/ZNF24/GPC1/ANK2/SH3TC2/MTOR/BCAS1/KIF14/EIF2B2	22
BP	GO:0030260	entry into host cell	22/2486	134/18670	0.1741	0.4158	0.3259	ITGB3/ITGB5/CAV2/IFITM3/TRIM21/GAS6/ITCH/EGFR/NUP153/KPNA3/CBL/EFNB2/IDE/TNFRSF14/IFITM2/UVRAG/CAV1/GYPA/ITGA2/GPR15/HYAL1/AXL	22
BP	GO:0044409	entry into host	22/2486	134/18670	0.1741	0.4158	0.3259	ITGB3/ITGB5/CAV2/IFITM3/TRIM21/GAS6/ITCH/EGFR/NUP153/KPNA3/CBL/EFNB2/IDE/TNFRSF14/IFITM2/UVRAG/CAV1/GYPA/ITGA2/GPR15/HYAL1/AXL	22
BP	GO:0051806	entry into cell of other organism involved in symbiotic interaction	22/2486	134/18670	0.1741	0.4158	0.3259	ITGB3/ITGB5/CAV2/IFITM3/TRIM21/GAS6/ITCH/EGFR/NUP153/KPNA3/CBL/EFNB2/IDE/TNFRSF14/IFITM2/UVRAG/CAV1/GYPA/ITGA2/GPR15/HYAL1/AXL	22
BP	GO:0051828	entry into other organism involved in symbiotic interaction	22/2486	134/18670	0.1741	0.4158	0.3259	ITGB3/ITGB5/CAV2/IFITM3/TRIM21/GAS6/ITCH/EGFR/NUP153/KPNA3/CBL/EFNB2/IDE/TNFRSF14/IFITM2/UVRAG/CAV1/GYPA/ITGA2/GPR15/HYAL1/AXL	22
BP	GO:0048747	muscle fiber development	12/2486	67/18670	0.1744	0.416	0.326	CACNA2D2/CAV2/SGCD/LOX/UCHL1/OBSL1/SIX1/SMO/SHOX2/FLNC/SGCB/DMD	12
BP	GO:2000573	positive regulation of DNA biosynthetic process	12/2486	67/18670	0.1744	0.416	0.326	HSP90AA1/FBXO4/SMOC2/PKIB/CCT8/KLF4/PDGFRB/NOX4/PAK3/HSP90AB1/MAPKAPK5/NEK2	12
BP	GO:0019362	pyridine nucleotide metabolic process	30/2486	189/18670	0.1745	0.416	0.326	ME1/SLC4A1/NUP93/PFKFB2/DHTKD1/PARP9/ZBTB7A/NUP50/NNMT/QPRT/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/VCP/RAE1/NUP188/NUP160/NUP54/NADSYN1/NUP214/NUP155/FOXK2/NUPR1/SLC2A6/PRKAG2/NMNAT3/RPIA/PFKP	30
BP	GO:0046496	nicotinamide nucleotide metabolic process	30/2486	189/18670	0.1745	0.416	0.326	ME1/SLC4A1/NUP93/PFKFB2/DHTKD1/PARP9/ZBTB7A/NUP50/NNMT/QPRT/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/VCP/RAE1/NUP188/NUP160/NUP54/NADSYN1/NUP214/NUP155/FOXK2/NUPR1/SLC2A6/PRKAG2/NMNAT3/RPIA/PFKP	30
BP	GO:0002720	positive regulation of cytokine production involved in immune response	10/2486	54/18670	0.1747	0.416	0.326	TRIM6/BCL10/IL1R1/DDX21/TRAF6/TNFRSF14/IL1B/FZD5/WNT5A/RSAD2	10
BP	GO:0010524	positive regulation of calcium ion transport into cytosol	10/2486	54/18670	0.1747	0.416	0.326	SRI/PDPK1/SNCA/CX3CL1/P2RX7/RAMP3/APLNR/THY1/CAV1/BAK1	10
BP	GO:0045747	positive regulation of Notch signaling pathway	10/2486	54/18670	0.1747	0.416	0.326	EP300/TGFB2/HES1/JAG2/CREBBP/NOS3/MFNG/TSPAN14/NOTCH1/PDCD10	10
BP	GO:1904645	response to amyloid-beta	10/2486	54/18670	0.1747	0.416	0.326	CASP4/ITGA4/FCGR2B/IGF1R/IGF1/MMP3/MMP9/RAMP3/DNM1/TREM2	10
BP	GO:0050905	neuromuscular process	18/2486	107/18670	0.1751	0.4169	0.3267	HERC1/FXN/SLC1A3/ADARB1/CLN8/GCH1/UCHL1/HOXC10/AGTPBP1/FOXS1/TMEM150C/POU4F1/ALDH1A3/KCNA1/MYH10/GLRB/MYCBP2/PRRT2	18
BP	GO:0034142	toll-like receptor 4 signaling pathway	7/2486	35/18670	0.1763	0.4185	0.328	TNFAIP3/NFKBIA/LTF/RAB7B/LYN/TRIL/NR1H4	7
BP	GO:0042092	type 2 immune response	7/2486	35/18670	0.1763	0.4185	0.328	ARG2/ARG1/HLX/ECM1/BATF/IL33/RSAD2	7
BP	GO:0071108	protein K48-linked deubiquitination	7/2486	35/18670	0.1763	0.4185	0.328	TNFAIP3/OTUD4/UBXN1/USP7/CYLD/OTUD7B/USP33	7
BP	GO:0098801	regulation of renal system process	7/2486	35/18670	0.1763	0.4185	0.328	EDNRB/PTPRO/GAS6/GJA5/STC1/AGTR1/EMP2	7
BP	GO:1902991	regulation of amyloid precursor protein catabolic process	7/2486	35/18670	0.1763	0.4185	0.328	CLU/TNF/SORL1/IGF1/LYN/SPON1/PIN1	7
BP	GO:1904031	positive regulation of cyclin-dependent protein kinase activity	7/2486	35/18670	0.1763	0.4185	0.328	CCND1/EGFR/CCNT2/CCNYL2/CCNY/CDK5R1/HSP90AB1	7
BP	GO:1905332	positive regulation of morphogenesis of an epithelium	7/2486	35/18670	0.1763	0.4185	0.328	TGFB1/SIX1/HOXB7/SMO/SOX9/RREB1/MTOR	7
BP	GO:2000785	regulation of autophagosome assembly	7/2486	35/18670	0.1763	0.4185	0.328	SCFD1/PINK1/RAB3GAP2/SMCR8/MTM1/NUPR1/LRSAM1	7
BP	GO:0009152	purine ribonucleotide biosynthetic process	43/2486	280/18670	0.1767	0.419	0.3284	ADCY3/PDPR/GUCY2D/SLC4A1/SNCA/ADCY7/NUP93/TGFB1/PINK1/ADCY4/PFKFB2/LDHC/DHTKD1/FLCN/ZBTB7A/NUP50/NME5/ADCY6/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/ELOVL7/VCP/RAE1/NUP188/NUP160/NUP54/PDP1/NUP214/NUP155/FOXK2/AMPD2/NUPR1/SLC2A6/PRKAG2/TREM2/PFAS/PANK1/PDK4/ELOVL5/PFKP	43
BP	GO:0060047	heart contraction	43/2486	280/18670	0.1767	0.419	0.3284	SRI/SCN1B/ITPR1/CACNA2D2/MYL4/SMAD7/DLG1/TGFB2/ATP1B2/TPM1/CACNB3/ACE/GJA5/ZC3H12A/THRB/PDE4B/SGCD/EDN3/ASPH/JUP/GCH1/KCND3/NOS3/STC1/SLC1A1/KCNA5/CACNA2D3/IL2/FXYD1/NUP155/KCNK3/KCNJ8/TBX2/KCNK6/FKBP1B/ANK2/FLNA/RYR2/CAV1/MTOR/DMD/KCNK1/ADORA3	43
BP	GO:0098742	cell-cell adhesion via plasma-membrane adhesion molecules	42/2486	273/18670	0.1768	0.4191	0.3285	ANXA3/ACVR1/CLDN5/CD177/MBP/MYADM/ESAM/TGFB2/SELP/NEXN/L1CAM/PCDH11X/PCDHB1/CX3CL1/BMP2/GPC4/PCDH18/CLDN11/CEACAM6/CDH26/CEACAM8/PTPRF/CEACAM1/ROBO4/ITGAL/SDK1/PCDHB14/FAT1/KLF4/SPARCL1/PCDH17/CADM3/HMCN1/CDH5/IGSF9/PCDHGC5/IGSF21/PCDHB7/CDH6/CLDN10/CDH11/PCDHGA4	42
BP	GO:0005976	polysaccharide metabolic process	19/2486	114/18670	0.1776	0.4206	0.3296	CHIT1/CHST1/GNMT/TGFB1/SMPD3/UGP2/IGF1/EGF/IRS2/KHK/HAS2/PRKAG2/SORBS1/HAS3/PYGB/HAS1/MTOR/PPP1R3C/PHKA1	19
BP	GO:0008543	fibroblast growth factor receptor signaling pathway	19/2486	114/18670	0.1776	0.4206	0.3296	SPRY2/DSTYK/GALNT3/CRKL/HNRNPM/SPRY1/FGF18/SPRY4/SMOC2/POLR2G/FLRT2/CBL/SULF1/FRS2/CREB3L1/GPC1/WNT5A/KL/POLR2D	19
BP	GO:0042035	regulation of cytokine biosynthetic process	19/2486	114/18670	0.1776	0.4206	0.3296	INPP5D/INHBA/IRF1/TNF/BCL10/GHRL/ELANE/CD276/ZFP36/IRF4/TRAF6/HSPB1/RELA/KLF4/IL1B/WNT5A/TLR9/SPN/PTPRC	19
BP	GO:0009064	glutamine family amino acid metabolic process	13/2486	74/18670	0.1798	0.4243	0.3326	DDAH1/ARG2/ARG1/SLC1A3/MIR21/PYCR1/NOS3/ASS1/AADAT/CPS1/PFAS/GFPT2/NR1H4	13
BP	GO:0048199	vesicle targeting, to, from or within Golgi	13/2486	74/18670	0.1798	0.4243	0.3326	TRAPPC10/SCFD1/PEF1/CNIH3/CD59/TFG/SEC16A/F8/AP1AR/BET1/SEC24B/GOSR1/ARFGAP2	13
BP	GO:0050728	negative regulation of inflammatory response	27/2486	169/18670	0.1802	0.4243	0.3326	TNFAIP3/PPARG/C5orf30/PROC/FEM1A/PGLYRP1/ADCY7/DUSP10/GHRL/ELANE/FCGR2B/CX3CL1/ZC3H12A/PTGER4/CALCRL/WFDC1/IGF1/NR1D2/IL2/KLF4/ACP5/TEK/CDH5/ADCYAP1/PTPRC/NR1H4/NLRP7	27
BP	GO:0007628	adult walking behavior	6/2486	29/18670	0.1806	0.4243	0.3326	FXN/TRH/CLN8/DMRT3/UCHL1/GLRB	6
BP	GO:0008299	isoprenoid biosynthetic process	6/2486	29/18670	0.1806	0.4243	0.3326	DHRS9/IDI2/ALDH1A3/ALDH1A2/HMGCS1/RBP1	6
BP	GO:0010669	epithelial structure maintenance	6/2486	29/18670	0.1806	0.4243	0.3326	LDB1/SOX9/SERPINA3/MUC2/TLR9/ZNF830	6
BP	GO:0014044	Schwann cell development	6/2486	29/18670	0.1806	0.4243	0.3326	SIRT2/MPP5/PARD3/NTRK2/LGI4/SH3TC2	6
BP	GO:0021799	cerebral cortex radially oriented cell migration	6/2486	29/18670	0.1806	0.4243	0.3326	LHX6/P2RY12/GLI3/LAMB1/CDK5R1/SUN2	6
BP	GO:0021884	forebrain neuron development	6/2486	29/18670	0.1806	0.4243	0.3326	LHX6/PLXNA3/NRP1/WNT5A/SLIT2/LHX8	6
BP	GO:0042226	interleukin-6 biosynthetic process	6/2486	29/18670	0.1806	0.4243	0.3326	INPP5D/TNF/BCL10/GHRL/TRAF6/IL1B	6
BP	GO:0048261	negative regulation of receptor-mediated endocytosis	6/2486	29/18670	0.1806	0.4243	0.3326	ANKRD13D/UNC119/ANKRD13B/APOC1/ANKRD13A/SYT11	6
BP	GO:0048730	epidermis morphogenesis	6/2486	29/18670	0.1806	0.4243	0.3326	TGFB2/IGFBP5/SMO/KLF4/NOTCH1/INTU	6
BP	GO:0060441	epithelial tube branching involved in lung morphogenesis	6/2486	29/18670	0.1806	0.4243	0.3326	SPRY2/TNF/SPRY1/SOX9/YAP1/TNC	6
BP	GO:0070723	response to cholesterol	6/2486	29/18670	0.1806	0.4243	0.3326	GRAMD1B/INHBA/TGFB1/SMO/HMGCS1/GRAMD1C	6
BP	GO:2000765	regulation of cytoplasmic translation	6/2486	29/18670	0.1806	0.4243	0.3326	YTHDF2/DHX9/DNAJC24/CPEB1/MTOR/CPEB2	6
BP	GO:0006898	receptor-mediated endocytosis	48/2486	316/18670	0.1815	0.4243	0.3326	CLU/HBB/ITGB3/CTTN/NTF3/SCGB3A2/ITGA4/SPARC/ARF1/HSP90B1/CD9/SNCA/ANKRD13D/CAV2/UNC119/SORL1/HYOU1/FCGR2B/HSP90AA1/ANKRD13B/CXCR1/MSR1/APOC1/DAB2/CALCRL/FNBP1L/AP2A2/ANKRD13A/EGF/HP/RAMP2/HNRNPK/CBL/CEACAM1/SFRP4/EFNB2/WASF1/RAMP3/DNM1/FCHSD2/CCL21/COLEC12/MAGI2/FCHO1/CAV1/INPP5F/ARC/SYT11	48
BP	GO:0043268	positive regulation of potassium ion transport	9/2486	48/18670	0.1816	0.4243	0.3326	DLG1/ATP1B2/ADRA2A/MIR21/EDN3/KCNA1/TREM2/ANK2/FLNA	9
BP	GO:0044764	multi-organism cellular process	9/2486	48/18670	0.1816	0.4243	0.3326	PGLYRP1/LTF/GAS6/GPATCH3/IFIH1/TSPAN6/FCHSD2/RNF125/ZCCHC3	9
BP	GO:0051972	regulation of telomerase activity	9/2486	48/18670	0.1816	0.4243	0.3326	PPARG/PARP3/HSP90AA1/PKIB/KLF4/SMG6/HSP90AB1/MAPKAPK5/NEK2	9
BP	GO:0055023	positive regulation of cardiac muscle tissue growth	9/2486	48/18670	0.1816	0.4243	0.3326	TBX5/IGF1/MIR17HG/TBX2/NOTCH1/YAP1/ZFPM2/MTOR/PIN1	9
BP	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	29/2486	183/18670	0.1817	0.4243	0.3326	FADD/PRKCB/TNF/BCL10/LTF/PINK1/AKAP13/SLC20A1/MAP3K14/CX3CL1/TFG/DDX21/REL/TRAF6/ECM1/RELA/PLEKHG5/TSPAN6/PPM1A/IFIT5/IL1B/CCL21/FLNA/TLR9/ROR1/MAP3K3/SLC44A2/ALPK1/APOL3	29
BP	GO:0043487	regulation of RNA stability	29/2486	183/18670	0.1817	0.4243	0.3326	PSMD14/PSMD12/PABPC4/YTHDF2/FXR1/DHX9/PSMD7/HNRNPM/PSMB5/ZFP36/UBA52/LARP1/DCP2/ZC3H12A/EXOSC3/HSPB1/YWHAZ/NUP214/PSMB7/YBX1/PSMD1/PSMD9/UBC/SMG6/YTHDF3/MTOR/SET/PSME1/RC3H1	29
BP	GO:0006266	DNA ligation	4/2486	17/18670	0.1819	0.4243	0.3326	POLB/XRCC6/PARP3/MGMT	4
BP	GO:0006895	Golgi to endosome transport	4/2486	17/18670	0.1819	0.4243	0.3326	VPS13C/KLHL20/AP1AR/SYS1	4
BP	GO:0007379	segment specification	4/2486	17/18670	0.1819	0.4243	0.3326	IRX2/MEOX1/IRX3/MEOX2	4
BP	GO:0014733	regulation of skeletal muscle adaptation	4/2486	17/18670	0.1819	0.4243	0.3326	CAMK2G/GTF2IRD1/IGFBP5/MTOR	4
BP	GO:0015693	magnesium ion transport	4/2486	17/18670	0.1819	0.4243	0.3326	CNNM4/MMGT1/NIPAL2/TUSC3	4
BP	GO:0015732	prostaglandin transport	4/2486	17/18670	0.1819	0.4243	0.3326	P2RX7/TNFRSF11A/IL1B/SLCO2A1	4
BP	GO:0032460	negative regulation of protein oligomerization	4/2486	17/18670	0.1819	0.4243	0.3326	CLU/EP300/SORL1/CRYAB	4
BP	GO:0046500	S-adenosylmethionine metabolic process	4/2486	17/18670	0.1819	0.4243	0.3326	GNMT/AMD1/MAT2A/MTHFR	4
BP	GO:0048532	anatomical structure arrangement	4/2486	17/18670	0.1819	0.4243	0.3326	PLXNA3/NRP1/HSPA5/KIF14	4
BP	GO:0051284	positive regulation of sequestering of calcium ion	4/2486	17/18670	0.1819	0.4243	0.3326	SRI/TGFB1/FKBP1B/RYR2	4
BP	GO:0051709	regulation of killing of cells of other organism	4/2486	17/18670	0.1819	0.4243	0.3326	ARG1/PGLYRP1/P2RX7/CXCL6	4
BP	GO:0055070	copper ion homeostasis	4/2486	17/18670	0.1819	0.4243	0.3326	ARF1/ATP7B/MT2A/COX19	4
BP	GO:0098884	postsynaptic neurotransmitter receptor internalization	4/2486	17/18670	0.1819	0.4243	0.3326	ITGB3/EFNB2/DNM1/ARC	4
BP	GO:0140239	postsynaptic endocytosis	4/2486	17/18670	0.1819	0.4243	0.3326	ITGB3/EFNB2/DNM1/ARC	4
BP	GO:1903975	regulation of glial cell migration	4/2486	17/18670	0.1819	0.4243	0.3326	CSF1/CRKL/P2RY12/TREM2	4
BP	GO:1904948	midbrain dopaminergic neuron differentiation	4/2486	17/18670	0.1819	0.4243	0.3326	SFRP2/SFRP1/WNT5A/NR4A2	4
BP	GO:0030888	regulation of B cell proliferation	11/2486	61/18670	0.1819	0.4243	0.3326	INPP5D/FCGR2B/BTK/IRS2/IL2/VAV3/TLR9/CD300A/LYN/RC3H1/PTPRC	11
BP	GO:0016236	macroautophagy	45/2486	295/18670	0.1825	0.4246	0.3328	RRAGA/GABARAPL2/SCFD1/VPS13C/MAP1LC3A/TOMM20/ATP6V1E1/SQSTM1/PINK1/TECPR1/ERN1/LARP1/VPS37A/ATP6V0A2/RAB3GAP2/CHMP6/SIRT1/SESN2/SMCR8/UCHL1/ULK2/FYCO1/VCP/ATG4B/WAC/MTMR14/VPS37B/SESN3/FUNDC1/MTM1/NUPR1/LRSAM1/PRKAG2/RAB12/CDK5R1/UVRAG/DCN/VPS26B/MTOR/KDR/DYNLL2/GPSM1/TMEM74/HSPB8/SCOC	45
BP	GO:1903008	organelle disassembly	17/2486	101/18670	0.1829	0.4246	0.3328	CTTN/GABARAPL2/VPS13C/MAP1LC3A/PELO/SQSTM1/PINK1/DENR/FBXW7/VCP/FUNDC1/PLK3/ZFAND1/SPATA18/FZD5/KLC1/GFM2	17
BP	GO:0015740	C4-dicarboxylate transport	5/2486	23/18670	0.183	0.4246	0.3328	SLC1A3/LRRC8A/SLC1A1/LRRC8E/ABAT	5
BP	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules	5/2486	23/18670	0.183	0.4246	0.3328	CLDN5/CX3CL1/BMP2/CLDN11/CLDN10	5
BP	GO:0032717	negative regulation of interleukin-8 production	5/2486	23/18670	0.183	0.4246	0.3328	ELANE/KLF4/OTUD7B/SSC5D/TLR9	5
BP	GO:0032799	low-density lipoprotein receptor particle metabolic process	5/2486	23/18670	0.183	0.4246	0.3328	ITGB3/MYLIP/PPARG/AP2A2/HNRNPK	5
BP	GO:0051004	regulation of lipoprotein lipase activity	5/2486	23/18670	0.183	0.4246	0.3328	LPL/PCSK6/APOC1/ANGPTL4/GPIHBP1	5
BP	GO:0051882	mitochondrial depolarization	5/2486	23/18670	0.183	0.4246	0.3328	PPP2R3C/P2RX7/IFI6/DCN/KDR	5
BP	GO:0060479	lung cell differentiation	5/2486	23/18670	0.183	0.4246	0.3328	CREB1/THRB/NFIB/SOX9/YAP1	5
BP	GO:0070977	bone maturation	5/2486	23/18670	0.183	0.4246	0.3328	LTF/BMP2/SEMA4D/IGF1/THBS3	5
BP	GO:0071157	negative regulation of cell cycle arrest	5/2486	23/18670	0.183	0.4246	0.3328	CDK9/CCND1/MDM4/HSP90AB1/ZNF268	5
BP	GO:0099500	vesicle fusion to plasma membrane	5/2486	23/18670	0.183	0.4246	0.3328	STX2/STXBP1/SNAP23/STX4/PRRT2	5
BP	GO:1902254	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator	5/2486	23/18670	0.183	0.4246	0.3328	MUC1/MIR21/BDKRB2/SIRT1/TRIAP1	5
BP	GO:2000637	positive regulation of gene silencing by miRNA	5/2486	23/18670	0.183	0.4246	0.3328	FXR1/DHX9/TGFB1/ZFP36/EGFR	5
BP	GO:0010976	positive regulation of neuron projection development	43/2486	281/18670	0.1831	0.4246	0.3328	SCN1B/GRIP1/EP300/ARF1/BDNF/TRAK1/PLXNA3/CUX2/RND2/PACSIN1/NRP1/L1CAM/FBXO38/FBXW8/CX3CL1/FN1/NTRK2/AVIL/SEMA4D/OBSL1/SKIL/CXCL12/ITGA3/ITSN2/PTN/NIN/DPYSL3/IL2/SHOX2/PLXNA1/FKBP1B/WNT5A/PAK3/MAGI2/SLIT2/MTOR/LYN/ADCYAP1/FZD4/STYXL1/HSPA5/SHANK3/GDI1	43
BP	GO:0030100	regulation of endocytosis	43/2486	281/18670	0.1831	0.4246	0.3328	CLU/ITGB3/NTF3/CD177/PPARG/ARF1/CLIP3/SNCA/ANKRD13D/TUB/TNF/UNC119/TGFB1/C2/PACSIN1/GAS6/FCGR2B/ANKRD13B/APOC1/DAB2/ANKRD13A/EGF/HNRNPK/CBL/SFRP4/EFNB2/DNM1/LRSAM1/IL1B/CD300LF/CCL21/TREM2/PPP3CB/WNT5A/MAGI2/CD300A/CAV1/ITGA2/ARC/PTPRC/AXL/SYT11/CD151	43
BP	GO:0019722	calcium-mediated signaling	34/2486	218/18670	0.1835	0.4255	0.3335	SRI/PDPK1/ITPR1/EDNRB/FHL2/TNF/SPPL3/SELP/LMCD1/RCAN2/P2RY12/CXCR1/BTK/SGCD/GPR143/NFATC4/EGFR/P2RX7/IGF1/PTGFR/AGTR1/CALML4/FKBP1B/TREM2/PPP3CB/ANK2/RYR2/MTOR/KDR/DMD/DEFB1/PTPRC/NR5A2/NFATC3	34
BP	GO:0014855	striated muscle cell proliferation	14/2486	81/18670	0.1842	0.4267	0.3344	MAPK11/TBX5/TGFB2/AKIRIN1/SMAD1/FOXC1/SIX1/MIR17HG/SIX5/TBX2/NOTCH1/YAP1/JARID2/ZFPM2	14
BP	GO:1902930	regulation of alcohol biosynthetic process	14/2486	81/18670	0.1842	0.4267	0.3344	MBTPS1/SNCA/TNF/CD244/ERLIN1/NFYA/BMP2/ERLIN2/PTH1R/HRH1/IL1B/REST/HMGCS1/DKK3	14
BP	GO:1903533	regulation of protein targeting	14/2486	81/18670	0.1842	0.4267	0.3344	ABLIM3/STOM/BAG4/MFF/PINK1/ARIH2/CACNB3/FBXW7/MYO1C/FZD5/CDK5R1/UBE2D3/PDCD5/GDI1	14
BP	GO:0042129	regulation of T cell proliferation	25/2486	156/18670	0.187	0.4328	0.3392	HLA-DPB1/ARG2/FADD/ARG1/IRF1/DLG1/TGFB1/IGFBP2/CD276/HES1/TWSG1/MIR21/TRAF6/IL23R/IGF1/PDCD1LG2/IL12A/IL2/TNFRSF14/IL1B/GPNMB/SPN/RC3H1/PTPRC/CORO1A	25
BP	GO:0019915	lipid storage	12/2486	68/18670	0.1878	0.4342	0.3403	ITGB3/PPARG/NFKBIA/TNF/LPL/FBXW7/ZC3H12A/MSR1/SIRT1/BSCL2/IL1B/CAV1	12
BP	GO:0051965	positive regulation of synapse assembly	12/2486	68/18670	0.1878	0.4342	0.3403	BDNF/GHRL/CUX2/AGRN/TPBG/NTRK2/LRRN1/SEMA4D/FLRT2/SRPX2/OXTR/EPHB2	12
BP	GO:0022404	molting cycle process	15/2486	88/18670	0.188	0.4342	0.3403	INHBA/TNF/CD109/TGFB2/LDB1/NOM1/EGFR/RELA/IGFBP5/SMO/SOX9/NOTCH1/NSUN2/WNT5A/INTU	15
BP	GO:0022405	hair cycle process	15/2486	88/18670	0.188	0.4342	0.3403	INHBA/TNF/CD109/TGFB2/LDB1/NOM1/EGFR/RELA/IGFBP5/SMO/SOX9/NOTCH1/NSUN2/WNT5A/INTU	15
BP	GO:0070098	chemokine-mediated signaling pathway	15/2486	88/18670	0.188	0.4342	0.3403	CXCL5/SH2B3/CX3CL1/FOXC1/CXCR1/CCL13/GPR35/CXCL12/CXCL6/CCL21/TREM2/CXCL1/CCL8/SLIT2/CCL18	15
BP	GO:0098773	skin epidermis development	15/2486	88/18670	0.188	0.4342	0.3403	INHBA/TNF/CD109/TGFB2/LDB1/NOM1/EGFR/RELA/IGFBP5/SMO/SOX9/NOTCH1/NSUN2/WNT5A/INTU	15
BP	GO:1903321	negative regulation of protein modification by small protein conjugation or removal	15/2486	88/18670	0.188	0.4342	0.3403	TNFAIP3/SMAD7/DNAJA1/TRIM21/NXN/UBXN1/RELA/PRR7/DTX3L/CAMLG/CAV1/RPS7/MTOR/TAF1/TRIM44	15
BP	GO:0017145	stem cell division	8/2486	42/18670	0.1885	0.4347	0.3407	FGF13/NCOA3/TGFB2/PRDM15/WWTR1/SFRP2/CDK2AP2/NOTCH1	8
BP	GO:0044088	regulation of vacuole organization	8/2486	42/18670	0.1885	0.4347	0.3407	SCFD1/PINK1/RAB3GAP2/SMCR8/MTM1/NUPR1/LAPTM4B/LRSAM1	8
BP	GO:0099622	cardiac muscle cell membrane repolarization	8/2486	42/18670	0.1885	0.4347	0.3407	SCN1B/DLG1/GJA5/KCND3/KCNA5/KCNJ8/ANK2/FLNA	8
BP	GO:2001222	regulation of neuron migration	8/2486	42/18670	0.1885	0.4347	0.3407	ZNF609/NIPBL/CX3CL1/FLRT2/LRIG2/IGSF10/FLNA/GPR173	8
BP	GO:0043488	regulation of mRNA stability	28/2486	177/18670	0.1892	0.4361	0.3418	PSMD14/PSMD12/PABPC4/YTHDF2/FXR1/DHX9/PSMD7/HNRNPM/PSMB5/ZFP36/UBA52/LARP1/DCP2/ZC3H12A/EXOSC3/HSPB1/YWHAZ/NUP214/PSMB7/YBX1/PSMD1/PSMD9/UBC/YTHDF3/MTOR/SET/PSME1/RC3H1	28
BP	GO:0043954	cellular component maintenance	10/2486	55/18670	0.1897	0.4368	0.3423	CTTN/CD177/DLG1/PLEKHA7/FCGR2B/DLG2/IGF1R/ITGA3/PARD6A/MTHFR	10
BP	GO:0098900	regulation of action potential	10/2486	55/18670	0.1897	0.4368	0.3423	FGF13/DLG1/CACNB3/GJA5/JUP/GPR35/ANK2/FLNA/RYR2/CAV1	10
BP	GO:0019730	antimicrobial humoral response	20/2486	122/18670	0.1897	0.4368	0.3423	CLU/SLPI/CXCL5/CTSG/PPP2R3C/PGLYRP1/LTF/ELANE/LCN2/CAMP/CCL13/RARRES2/RNASE3/CXCL6/RPL39/PDZD11/PLA2G2A/CXCL1/PRSS2/DEFB1	20
BP	GO:0007626	locomotory behavior	31/2486	198/18670	0.1905	0.4383	0.3435	EPS8/NTAN1/TMOD1/NAV2/B4GALT2/SNCA/MCOLN3/FXN/TAL1/TRH/CLN8/DMRT3/UCHL1/SOBP/CXCL12/MTA1/LGI4/ALDH1A3/ANKH/PPP3CB/NCOA2/NR4A2/HPGDS/INPP5F/MTOR/FZD4/GLRB/HOXD9/OLFM2/ABAT/MYO15A	31
BP	GO:0051924	regulation of calcium ion transport	39/2486	254/18670	0.1906	0.4384	0.3436	SRI/PDPK1/CAMK2G/SNCA/TGFB1/FGF14/CACNB3/ADRA2A/DIAPH1/CX3CL1/MIR21/P2RY12/PDE4B/STAC/NOS3/STC1/P2RX7/MCHR1/GPR35/PML/CXCL12/EGF/STAC2/AHNAK/RAMP3/APLNR/PDGFRB/FKBP1B/THY1/ANK2/TLR9/RYR2/CAV1/STC2/LYN/BAK1/DMD/WFS1/CORO1A	39
BP	GO:0006813	potassium ion transport	37/2486	240/18670	0.1909	0.4389	0.344	KCNK17/SLC24A3/KCNC4/DLG1/KCNJ15/ATP1B2/SLC1A3/ADRA2A/KCNN3/GJA5/KCNA6/MIR21/P2RY12/EDN3/KCND3/NOS3/SLC12A8/KCNK10/SLC24A5/KCNA5/KCNMA1/AQP1/FXYD1/KCNK3/KCNJ8/KCNK6/KCNA1/TREM2/ANK2/TRPM5/FLNA/KCNT2/CAV1/ADCYAP1/KCNS3/KCNK1/KCNA3	37
BP	GO:0044070	regulation of anion transport	16/2486	95/18670	0.1913	0.4395	0.3445	ARG1/SNCA/CYP4F2/TRH/STXBP1/STC1/P2RX7/TNFRSF11A/IRS2/SFRP4/IL1B/MTOR/TRIAP1/FABP3/SLC6A1/ABAT	16
BP	GO:0055006	cardiac cell development	16/2486	95/18670	0.1913	0.4395	0.3445	YY1/SPRY1/AKAP13/MIR21/SGCD/OBSL1/IGF1/PDGFRA/ALPK3/PDGFRB/NOTCH1/SGCB/ALPK2/MTOR/MYH10/PIN1	16
BP	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	13/2486	75/18670	0.1927	0.4422	0.3466	PSMD14/PSMD12/ITGB5/PSMD7/PDIA3/PSMB5/HLA-B/PSMB7/SNAP23/PSMD1/PSMD9/PSME1/HLA-A	13
BP	GO:0021536	diencephalon development	13/2486	75/18670	0.1927	0.4422	0.3466	CREB1/HES1/NRP1/BMP2/PTN/SMO/POU4F1/ALDH1A2/WNT5A/MSX1/NR4A2/ADCYAP1/NCOA1	13
BP	GO:1903201	regulation of oxidative stress-induced cell death	13/2486	75/18670	0.1927	0.4422	0.3466	NOL3/SFPQ/PINK1/FBXW7/MIR21/PYCR1/SIRT1/NME5/HSPB1/MMP3/MCL1/REST/NONO	13
BP	GO:0106106	cold-induced thermogenesis	23/2486	143/18670	0.194	0.445	0.3488	GRB10/APC/FABP5/GHRL/LCN2/KDM6B/FLCN/IGF1R/IRF4/GPR3/DDIT3/ADIPOR2/HOXC10/ACOT13/MFAP2/BSCL2/NOTCH1/DIO2/ZNF423/OXTR/EBF2/CAV1/ADCYAP1	23
BP	GO:0120161	regulation of cold-induced thermogenesis	23/2486	143/18670	0.194	0.445	0.3488	GRB10/APC/FABP5/GHRL/LCN2/KDM6B/FLCN/IGF1R/IRF4/GPR3/DDIT3/ADIPOR2/HOXC10/ACOT13/MFAP2/BSCL2/NOTCH1/DIO2/ZNF423/OXTR/EBF2/CAV1/ADCYAP1	23
BP	GO:0002385	mucosal immune response	7/2486	36/18670	0.1954	0.4475	0.3507	LTF/CAMP/RNASE3/PIGR/RPL39/OTUD7B/DEFB1	7
BP	GO:0034390	smooth muscle cell apoptotic process	7/2486	36/18670	0.1954	0.4475	0.3507	PPARG/MIR21/SIRT1/IGF1/STK4/IL12A/PDE1A	7
BP	GO:0034391	regulation of smooth muscle cell apoptotic process	7/2486	36/18670	0.1954	0.4475	0.3507	PPARG/MIR21/SIRT1/IGF1/STK4/IL12A/PDE1A	7
BP	GO:0090322	regulation of superoxide metabolic process	7/2486	36/18670	0.1954	0.4475	0.3507	CD177/TNF/TGFB1/MIR21/GCH1/EGFR/ACP5	7
BP	GO:0097242	amyloid-beta clearance	7/2486	36/18670	0.1954	0.4475	0.3507	CLU/MME/TNF/IGF1R/MSR1/IDE/TREM2	7
BP	GO:0051650	establishment of vesicle localization	44/2486	290/18670	0.1957	0.448	0.3511	TRAPPC10/SCFD1/PEF1/ASIP/ITGA4/ARF1/STX2/TRAK1/CNIH3/PRKCB/SNCA/CD59/DYNC1I1/PINK1/LRMP/CLASP2/STXBP1/WDR11/TFG/GPR143/FNBP1L/P2RX7/SEC16A/F8/MLPH/FYCO1/CADPS2/AP1AR/MAP2/BET1/SEC24B/DNM1/MYO1C/SNAP23/GOSR1/STX4/NDE1/TBC1D23/ARFGAP2/CLASP1/UNC13B/GIPC1/PRRT2/SYT11	44
BP	GO:0010676	positive regulation of cellular carbohydrate metabolic process	11/2486	62/18670	0.1963	0.4488	0.3518	PMAIP1/SNCA/CD244/PFKFB2/WDR5/SIRT1/IGF1/PTH1R/IRS2/HRH1/SORBS1	11
BP	GO:0032623	interleukin-2 production	11/2486	62/18670	0.1963	0.4488	0.3518	TNFAIP3/NAV3/ZFP36/CD83/IRF4/PDE4B/TRAF6/CD34/IL1B/PTPRC/NR1H4	11
BP	GO:0030279	negative regulation of ossification	14/2486	82/18670	0.1967	0.4495	0.3523	GATA1/BCOR/TNF/TWIST1/TGFB1/TWSG1/TWIST2/ECM1/SEMA4D/IGFBP5/SOX9/NOTCH1/SFRP1/LRP5	14
BP	GO:0051279	regulation of release of sequestered calcium ion into cytosol	14/2486	82/18670	0.1967	0.4495	0.3523	SRI/PDPK1/SNCA/TGFB1/DIAPH1/CX3CL1/APLNR/FKBP1B/THY1/ANK2/RYR2/LYN/DMD/CORO1A	14
BP	GO:0002686	negative regulation of leukocyte migration	9/2486	49/18670	0.1979	0.4515	0.3538	HOXA7/PTGER4/CXCL12/PLCB1/CCL21/IL33/DUSP1/CD300A/SLIT2	9
BP	GO:0010712	regulation of collagen metabolic process	9/2486	49/18670	0.1979	0.4515	0.3538	PPARG/TGFB1/CYGB/PDGFRB/CREB3L1/FAP/ITGA2/MFAP4/LARP6	9
BP	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	9/2486	49/18670	0.1979	0.4515	0.3538	TNFAIP3/USP10/TNIP1/ZC3H12A/SIRT1/PPM1A/OTUD7B/PER1/NR1H4	9
BP	GO:0071715	icosanoid transport	9/2486	49/18670	0.1979	0.4515	0.3538	CYP4F2/PLA2G5/ACE/BDKRB2/P2RX7/TNFRSF11A/IL1B/PLA2G2A/SLCO2A1	9
BP	GO:1901571	fatty acid derivative transport	9/2486	49/18670	0.1979	0.4515	0.3538	CYP4F2/PLA2G5/ACE/BDKRB2/P2RX7/TNFRSF11A/IL1B/PLA2G2A/SLCO2A1	9
BP	GO:0006661	phosphatidylinositol biosynthetic process	19/2486	116/18670	0.1983	0.4521	0.3544	BMX/INPP5D/ARF1/PTPN13/PIGH/PLEKHA4/PLEKHA3/PLEKHA2/PIGX/PIGA/MTMR14/PIK3CD/MTM1/MTMR12/PIGY/INPP5F/PIGL/MTMR7/MTMR4	19
BP	GO:0016042	lipid catabolic process	50/2486	333/18670	0.1989	0.4533	0.3553	PLD4/SIRT2/PLA2G4C/LIPJ/ACAD10/LIPA/DAGLB/CPT1C/TNF/TWIST1/HSD3B7/FABP5/LPL/SCT/CYP4F2/SORL1/CYP4F3/PLA2G5/MGLL/CYP26B1/ADRA2A/SMPD3/ETFDH/APOC1/SESN2/SPP1/PDXDC1/RARRES2/ACAT2/NAAA/HSD17B14/PLCB2/PLCB1/IRS2/GDPD1/CRABP1/BSCL2/ETFA/IL1B/PLA2G2A/PLCD4/CPS1/ACBD5/ENPP2/AKR1D1/CRAT/INPP5F/MTOR/CYP39A1/FABP3	50
BP	GO:0051188	cofactor biosynthetic process	49/2486	326/18670	0.1995	0.4546	0.3563	ALAS2/PPTC7/PDPR/SLC4A1/UROD/SNCA/FXN/NUP93/IREB2/PFKFB2/GGT5/ABCB6/COQ10B/DHTKD1/PARP9/ZBTB7A/NUP50/GCH1/NNMT/QPRT/P2RX7/PTS/CBFA2T3/IGF1/NUP153/LIAS/NUP210/ELOVL7/RAE1/NUP188/NUP160/NUP54/PDP1/NADSYN1/NUP214/NUP155/FOXK2/NUPR1/SLC2A6/PRKAG2/TPK1/PANK1/MAT2A/MMACHC/ALAS1/PDK4/NMNAT3/ELOVL5/PFKP	49
BP	GO:0042089	cytokine biosynthetic process	20/2486	123/18670	0.1999	0.4554	0.3569	INPP5D/INHBA/IRF1/TNF/BCL10/GHRL/ELANE/CD276/ZFP36/IRF4/CEBPE/TRAF6/HSPB1/RELA/KLF4/IL1B/WNT5A/TLR9/SPN/PTPRC	20
BP	GO:0032465	regulation of cytokinesis	15/2486	89/18670	0.2001	0.4556	0.3571	CIT/RAB11FIP4/FLCN/BCL2L1/PKP4/PLK3/PLK1/KIF20A/UVRAG/PKN2/E2F8/GIPC1/SETD2/KIF14/PIN1	15
BP	GO:0002828	regulation of type 2 immune response	6/2486	30/18670	0.202	0.4577	0.3587	ARG2/ARG1/HLX/ECM1/IL33/RSAD2	6
BP	GO:0021696	cerebellar cortex morphogenesis	6/2486	30/18670	0.202	0.4577	0.3587	FAIM2/HERC1/LDB1/AGTPBP1/SMO/KIF14	6
BP	GO:0032743	positive regulation of interleukin-2 production	6/2486	30/18670	0.202	0.4577	0.3587	CD83/IRF4/PDE4B/TRAF6/IL1B/PTPRC	6
BP	GO:0045939	negative regulation of steroid metabolic process	6/2486	30/18670	0.202	0.4577	0.3587	ERLIN1/BMP2/ERLIN2/REST/DKK3/NR1H4	6
BP	GO:0048265	response to pain	6/2486	30/18670	0.202	0.4577	0.3587	EDNRB/TACR1/GJA4/THBS4/GCH1/VWA1	6
BP	GO:0051491	positive regulation of filopodium assembly	6/2486	30/18670	0.202	0.4577	0.3587	AGRN/NRP1/FNBP1L/DPYSL3/CCL21/DOCK11	6
BP	GO:0071549	cellular response to dexamethasone stimulus	6/2486	30/18670	0.202	0.4577	0.3587	ARG1/TGFB1/EGFR/ASS1/AQP1/NR3C1	6
BP	GO:0099068	postsynapse assembly	6/2486	30/18670	0.202	0.4577	0.3587	GAP43/WNT5A/MAGI2/NLGN4X/EPHB2/SHANK3	6
BP	GO:0006835	dicarboxylic acid transport	16/2486	96/18670	0.203	0.4577	0.3587	SNCA/SLC1A3/TRH/STXBP1/LRRC8A/CLN8/NTRK2/P2RX7/SLC26A10/SLC1A1/SLC26A6/LRRC8E/SLC26A8/UNC13B/GIPC1/ABAT	16
BP	GO:0030219	megakaryocyte differentiation	16/2486	96/18670	0.203	0.4577	0.3587	MYL9/SH2B3/CNOT4/EP300/GATA1/WASF2/TAL1/TNRC6B/WDR5/SP3/LOX/FLI1/RAB7B/CDKN2B/GP1BA/SIN3A	16
BP	GO:0022618	ribonucleoprotein complex assembly	42/2486	277/18670	0.2034	0.4577	0.3587	RPS27/RPS28/CPSF7/EIF5/LSM4/RPS27L/EIF3L/EIF4B/YTHDC1/CLNS1A/NOL3/DHX9/RPS15/DENR/SRPK2/EIF2S1/HSP90AA1/G3BP2/MRPL20/RPL10/EIF2A/EIF4H/EIF3F/RSL24D1/GEMIN6/ATXN2L/SNRPB/CELF1/RPS10/RPL6/NUFIP1/SF3B1/RBMX/EIF3K/EIF3M/CNOT7/HSP90AB1/STYXL1/POLR2D/RC3H1/DDX6/CNOT1	42
BP	GO:0030534	adult behavior	23/2486	144/18670	0.2035	0.4577	0.3587	EPS8/NTAN1/ASIP/TMOD1/FADD/SNCA/FXN/GHRL/TRH/CLN8/DMRT3/UCHL1/CXCL12/SDK1/LGI4/PCDH17/NR4A2/INPP5F/NLGN4X/GLRB/HOXD9/SHANK3/ABAT	23
BP	GO:0009132	nucleoside diphosphate metabolic process	25/2486	158/18670	0.205	0.4577	0.3587	SLC4A1/DLG1/NUP93/PFKFB2/DHTKD1/DLG2/ZBTB7A/NUP50/NME5/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/RAE1/NUP188/NUP160/NUP54/NUP214/NUP155/FOXK2/NUPR1/SLC2A6/PRKAG2/PFKP	25
BP	GO:0046148	pigment biosynthetic process	10/2486	56/18670	0.2053	0.4577	0.3587	ALAS2/ASIP/UROD/FXN/IREB2/GPR143/SLC24A5/WNT5A/ALAS1/GIPC1	10
BP	GO:0050954	sensory perception of mechanical stimulus	26/2486	165/18670	0.2055	0.4577	0.3587	SPRY2/COCH/SLC9A3R1/MBP/NAV2/NIPBL/TUB/SLC1A3/TIMM10/CACNB3/DIAPH1/THRB/LOXHD1/SOBP/CXCL12/SIX1/GJB6/LRIG2/KCNA1/ROR1/TBX1/ITGA2/FZD4/WFS1/ALDH7A1/MYO15A	26
BP	GO:0032874	positive regulation of stress-activated MAPK cascade	27/2486	172/18670	0.2059	0.4577	0.3587	MMP8/TNF/TGFB2/TRAF4/FCGR2B/ERN1/ZC3H12A/BMP2/TRAF6/MAP3K2/SAMD5/MAP3K5/TPD52L1/PLCB1/TNFRSF11A/FZD10/MID1/IL1B/CCL21/FZD5/PDCD10/WNT5A/TLR9/IL26/MAP3K3/FZD4/RASSF2	27
BP	GO:0046785	microtubule polymerization	13/2486	76/18670	0.206	0.4577	0.3587	FGF13/NAV3/CLIP3/SNCA/FKBP4/CLASP2/CEP192/NIN/MAP2/CDK5R1/NDE1/CDH5/CLASP1	13
BP	GO:2001020	regulation of response to DNA damage stimulus	33/2486	214/18670	0.2064	0.4577	0.3587	CLU/MUC1/PMAIP1/BCLAF1/PARP3/ANKLE1/TWIST1/DHX9/KLHL15/CDK9/FUS/HELB/MIR21/PARP9/IER3/FBXO4/DDX11/SIRT1/EGFR/BCL2L1/SFRP2/PML/SKIL/CXCL12/HNRNPK/MCL1/DTX3L/WDR70/MSX1/TRIAP1/MGMT/SETD2/RNF8	33
BP	GO:0070507	regulation of microtubule cytoskeleton organization	29/2486	186/18670	0.2064	0.4577	0.3587	RBM14/FGF13/RASSF1/PARP3/NAV3/CLIP3/APC/SNCA/FKBP4/CLASP2/TPX2/CHMP1B/MDM1/CYLD/SENP6/CDK2AP2/RAE1/PHLDB2/NIN/MAP2/TTBK2/MID1/PLK1/CDK5R1/FAM107A/CDH5/CLASP1/TMEM67/NEK2	29
BP	GO:0001953	negative regulation of cell-matrix adhesion	8/2486	43/18670	0.2065	0.4577	0.3587	ARHGAP6/HOXA7/CLASP2/PHLDB2/FAM107A/DLC1/POSTN/SEMA3E	8
BP	GO:0021762	substantia nigra development	8/2486	43/18670	0.2065	0.4577	0.3587	SIRT2/MBP/SEC16A/SYPL2/SUDS3/HSPA5/MAPKAP1/ZNF430	8
BP	GO:0043616	keratinocyte proliferation	8/2486	43/18670	0.2065	0.4577	0.3587	CD109/ZFP36/MIR21/EFNB2/HAS2/NOTCH2/YAP1/INTU	8
BP	GO:0045687	positive regulation of glial cell differentiation	8/2486	43/18670	0.2065	0.4577	0.3587	PPARG/TGFB1/HES1/BMP2/RELA/PTN/NOTCH1/MTOR	8
BP	GO:0055026	negative regulation of cardiac muscle tissue development	8/2486	43/18670	0.2065	0.4577	0.3587	YY1/MAPK11/TBX5/BMP2/MIR17HG/FRS2/JARID2/SOX6	8
BP	GO:0060612	adipose tissue development	8/2486	43/18670	0.2065	0.4577	0.3587	LRP5L/CSF1/GHRL/SORL1/SIRT1/EBF2/NR1H4/LRP5	8
BP	GO:0071364	cellular response to epidermal growth factor stimulus	8/2486	43/18670	0.2065	0.4577	0.3587	PDPK1/BAG4/ZFP36/FOXC1/EGFR/EEF1A1/CBL/SOX9	8
BP	GO:0072348	sulfur compound transport	8/2486	43/18670	0.2065	0.4577	0.3587	SLC35F3/SLC9A3R1/LRRC8A/SLC26A10/SLC1A1/SLC26A6/SLC7A9/SLC26A8	8
BP	GO:0006733	oxidoreduction coenzyme metabolic process	32/2486	207/18670	0.2065	0.4577	0.3587	PPTC7/ME1/SLC4A1/NUP93/PFKFB2/COQ10B/DHTKD1/PARP9/ZBTB7A/NUP50/NNMT/QPRT/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/VCP/RAE1/NUP188/NUP160/NUP54/NADSYN1/NUP214/NUP155/FOXK2/NUPR1/SLC2A6/PRKAG2/NMNAT3/RPIA/PFKP	32
BP	GO:0072522	purine-containing compound biosynthetic process	47/2486	313/18670	0.2072	0.4577	0.3587	ADCY3/GMPR/PDPR/GUCY2D/SLC4A1/AMD1/SNCA/ADCY7/NUP93/TGFB1/PINK1/ADCY4/PFKFB2/LDHC/DHTKD1/FLCN/ZBTB7A/NUP50/PRTFDC1/NME5/NOS3/ADCY6/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/ELOVL7/VCP/RAE1/NUP188/NUP160/NUP54/PDP1/NUP214/NUP155/FOXK2/AMPD2/NUPR1/SLC2A6/PRKAG2/TREM2/PFAS/PANK1/PDK4/ELOVL5/PFKP	47
BP	GO:0001919	regulation of receptor recycling	5/2486	24/18670	0.2076	0.4577	0.3587	SNCA/AP1AR/TBC1D16/RAMP3/INPP5F	5
BP	GO:0002227	innate immune response in mucosa	5/2486	24/18670	0.2076	0.4577	0.3587	LTF/CAMP/RNASE3/RPL39/DEFB1	5
BP	GO:0003272	endocardial cushion formation	5/2486	24/18670	0.2076	0.4577	0.3587	ACVR1/HEYL/TGFB2/NOTCH1/MSX1	5
BP	GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway	5/2486	24/18670	0.2076	0.4577	0.3587	SLC9A3R1/SNCA/LOX/CBL/LRIG2	5
BP	GO:0032897	negative regulation of viral transcription	5/2486	24/18670	0.2076	0.4577	0.3587	JUN/IFITM3/TRIM21/ZFP36/REST	5
BP	GO:0032925	regulation of activin receptor signaling pathway	5/2486	24/18670	0.2076	0.4577	0.3587	ACVR1/SMAD7/ACVR2A/DACT2/MAGI2	5
BP	GO:0034629	cellular protein-containing complex localization	5/2486	24/18670	0.2076	0.4577	0.3587	SMAD7/DLG1/SGCD/EXOC3L2/STXBP6	5
BP	GO:0036315	cellular response to sterol	5/2486	24/18670	0.2076	0.4577	0.3587	GRAMD1B/INHBA/SMO/HMGCS1/GRAMD1C	5
BP	GO:0045603	positive regulation of endothelial cell differentiation	5/2486	24/18670	0.2076	0.4577	0.3587	CLDN5/PROC/MIR21/NOTCH1/CDH5	5
BP	GO:0046475	glycerophospholipid catabolic process	5/2486	24/18670	0.2076	0.4577	0.3587	PLA2G4C/APOC1/GDPD1/ENPP2/INPP5F	5
BP	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway	5/2486	24/18670	0.2076	0.4577	0.3587	PRKCB/CYLD/RELA/CMTM3/PTPRC	5
BP	GO:0060148	positive regulation of posttranscriptional gene silencing	5/2486	24/18670	0.2076	0.4577	0.3587	FXR1/DHX9/TGFB1/ZFP36/EGFR	5
BP	GO:0090103	cochlea morphogenesis	5/2486	24/18670	0.2076	0.4577	0.3587	SIX1/SOX9/CTHRC1/WNT5A/TBX1	5
BP	GO:1900078	positive regulation of cellular response to insulin stimulus	5/2486	24/18670	0.2076	0.4577	0.3587	SORL1/SIRT1/MYO1C/SORBS1/NR1H4	5
BP	GO:1903421	regulation of synaptic vesicle recycling	5/2486	24/18670	0.2076	0.4577	0.3587	SNCA/FGF14/DNM1/PPP3CB/SYT11	5
BP	GO:2001026	regulation of endothelial cell chemotaxis	5/2486	24/18670	0.2076	0.4577	0.3587	FGF18/HSPB1/SMOC2/NOTCH1/KDR	5
BP	GO:0002024	diet induced thermogenesis	3/2486	12/18670	0.2078	0.4577	0.3587	SCT/SORL1/BMP8A	3
BP	GO:0002674	negative regulation of acute inflammatory response	3/2486	12/18670	0.2078	0.4577	0.3587	PPARG/FCGR2B/ADCYAP1	3
BP	GO:0003161	cardiac conduction system development	3/2486	12/18670	0.2078	0.4577	0.3587	TBX5/GJA5/NOTCH1	3
BP	GO:0003207	cardiac chamber formation	3/2486	12/18670	0.2078	0.4577	0.3587	TBX5/TBX2/NOTCH1	3
BP	GO:0006465	signal peptide processing	3/2486	12/18670	0.2078	0.4577	0.3587	SPPL3/SPCS1/SPCS3	3
BP	GO:0010452	histone H3-K36 methylation	3/2486	12/18670	0.2078	0.4577	0.3587	BCOR/NSD1/SETD2	3
BP	GO:0010826	negative regulation of centrosome duplication	3/2486	12/18670	0.2078	0.4577	0.3587	RBM14/MDM1/TMEM67	3
BP	GO:0021559	trigeminal nerve development	3/2486	12/18670	0.2078	0.4577	0.3587	PLXNA3/NRP1/POU4F1	3
BP	GO:0030208	dermatan sulfate biosynthetic process	3/2486	12/18670	0.2078	0.4577	0.3587	BGN/DCN/CSPG4	3
BP	GO:0031392	regulation of prostaglandin biosynthetic process	3/2486	12/18670	0.2078	0.4577	0.3587	FABP5/SIRT1/IL1B	3
BP	GO:0034309	primary alcohol biosynthetic process	3/2486	12/18670	0.2078	0.4577	0.3587	BMP2/REST/DKK3	3
BP	GO:0035630	bone mineralization involved in bone maturation	3/2486	12/18670	0.2078	0.4577	0.3587	LTF/BMP2/IGF1	3
BP	GO:0043696	dedifferentiation	3/2486	12/18670	0.2078	0.4577	0.3587	NCOA3/MIR214/OLFM2	3
BP	GO:0043697	cell dedifferentiation	3/2486	12/18670	0.2078	0.4577	0.3587	NCOA3/MIR214/OLFM2	3
BP	GO:0044650	adhesion of symbiont to host cell	3/2486	12/18670	0.2078	0.4577	0.3587	GAS6/LRRC15/HSP90AB1	3
BP	GO:0045080	positive regulation of chemokine biosynthetic process	3/2486	12/18670	0.2078	0.4577	0.3587	TNF/IL1B/WNT5A	3
BP	GO:0045472	response to ether	3/2486	12/18670	0.2078	0.4577	0.3587	LARP1/ZC3H12A/NFATC4	3
BP	GO:0045579	positive regulation of B cell differentiation	3/2486	12/18670	0.2078	0.4577	0.3587	INPP5D/PPP2R3C/BTK	3
BP	GO:0045955	negative regulation of calcium ion-dependent exocytosis	3/2486	12/18670	0.2078	0.4577	0.3587	ADRA2A/NOTCH1/REST	3
BP	GO:0048642	negative regulation of skeletal muscle tissue development	3/2486	12/18670	0.2078	0.4577	0.3587	TWIST1/AKIRIN1/TGFB1	3
BP	GO:0051095	regulation of helicase activity	3/2486	12/18670	0.2078	0.4577	0.3587	MSH6/SIRT1/IFIT1	3
BP	GO:0051132	NK T cell activation	3/2486	12/18670	0.2078	0.4577	0.3587	IL23R/IL12A/CD300A	3
BP	GO:0051481	negative regulation of cytosolic calcium ion concentration	3/2486	12/18670	0.2078	0.4577	0.3587	GTF2I/KCNA5/KCNK3	3
BP	GO:0051549	positive regulation of keratinocyte migration	3/2486	12/18670	0.2078	0.4577	0.3587	MMP9/HAS2/MTOR	3
BP	GO:0051798	positive regulation of hair follicle development	3/2486	12/18670	0.2078	0.4577	0.3587	TNF/TGFB2/WNT5A	3
BP	GO:0051988	regulation of attachment of spindle microtubules to kinetochore	3/2486	12/18670	0.2078	0.4577	0.3587	SIRT2/APC/NEK2	3
BP	GO:0060670	branching involved in labyrinthine layer morphogenesis	3/2486	12/18670	0.2078	0.4577	0.3587	RSPO3/FZD5/SPINT2	3
BP	GO:0060788	ectodermal placode formation	3/2486	12/18670	0.2078	0.4577	0.3587	SIX1/FRS2/TBX2	3
BP	GO:0070493	thrombin-activated receptor signaling pathway	3/2486	12/18670	0.2078	0.4577	0.3587	SNCA/HPGD/GP1BA	3
BP	GO:0070586	cell-cell adhesion involved in gastrulation	3/2486	12/18670	0.2078	0.4577	0.3587	MBP/MYADM/KLF4	3
BP	GO:0071472	cellular response to salt stress	3/2486	12/18670	0.2078	0.4577	0.3587	XRCC6/AQP1/EFHD1	3
BP	GO:0071697	ectodermal placode morphogenesis	3/2486	12/18670	0.2078	0.4577	0.3587	SIX1/FRS2/TBX2	3
BP	GO:0072540	T-helper 17 cell lineage commitment	3/2486	12/18670	0.2078	0.4577	0.3587	IRF4/IL23R/BATF	3
BP	GO:0072578	neurotransmitter-gated ion channel clustering	3/2486	12/18670	0.2078	0.4577	0.3587	SSH1/GLRB/SHANK3	3
BP	GO:0072697	protein localization to cell cortex	3/2486	12/18670	0.2078	0.4577	0.3587	RTKN/ANLN/PLK1	3
BP	GO:0097104	postsynaptic membrane assembly	3/2486	12/18670	0.2078	0.4577	0.3587	MAGI2/NLGN4X/EPHB2	3
BP	GO:0098974	postsynaptic actin cytoskeleton organization	3/2486	12/18670	0.2078	0.4577	0.3587	ARF1/WASF2/MYH10	3
BP	GO:0099550	trans-synaptic signaling, modulating synaptic transmission	3/2486	12/18670	0.2078	0.4577	0.3587	NTRK2/PLAT/EPHB2	3
BP	GO:0099640	axo-dendritic protein transport	3/2486	12/18670	0.2078	0.4577	0.3587	SFPQ/DLG2/HSPB1	3
BP	GO:1900165	negative regulation of interleukin-6 secretion	3/2486	12/18670	0.2078	0.4577	0.3587	GAS6/ZC3H12A/SYT11	3
BP	GO:1900402	regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter	3/2486	12/18670	0.2078	0.4577	0.3587	MLXIP/WDR5/FOXK2	3
BP	GO:1902287	semaphorin-plexin signaling pathway involved in axon guidance	3/2486	12/18670	0.2078	0.4577	0.3587	PLXNA3/NRP1/PLXNA1	3
BP	GO:1902337	regulation of apoptotic process involved in morphogenesis	3/2486	12/18670	0.2078	0.4577	0.3587	TGFB2/FOXC1/NOTCH1	3
BP	GO:1904181	positive regulation of membrane depolarization	3/2486	12/18670	0.2078	0.4577	0.3587	P2RX7/DCN/KDR	3
BP	GO:1904668	positive regulation of ubiquitin protein ligase activity	3/2486	12/18670	0.2078	0.4577	0.3587	UBE2S/PLK1/UBE2C	3
BP	GO:2000121	regulation of removal of superoxide radicals	3/2486	12/18670	0.2078	0.4577	0.3587	TNF/MIR21/GCH1	3
BP	GO:2001053	regulation of mesenchymal cell apoptotic process	3/2486	12/18670	0.2078	0.4577	0.3587	SOX9/MSX1/TBX1	3
BP	GO:0051648	vesicle localization	46/2486	306/18670	0.2079	0.4577	0.3587	TRAPPC10/SCFD1/PEF1/ASIP/ITGA4/ARF1/STX2/TRAK1/CNIH3/PRKCB/SNCA/CD59/DYNC1I1/PINK1/LRMP/CLASP2/STXBP1/WDR11/TFG/GPR143/FNBP1L/P2RX7/SEC16A/F8/MLPH/FYCO1/CADPS2/AP1AR/MAP2/BET1/SEC24B/DNM1/MYO1C/PCDH17/SNAP23/GOSR1/STX4/NDE1/TBC1D23/ARFGAP2/MAGI2/CLASP1/UNC13B/GIPC1/PRRT2/SYT11	46
BP	GO:0045913	positive regulation of carbohydrate metabolic process	14/2486	83/18670	0.2096	0.4605	0.361	PMAIP1/SNCA/CD244/PFKFB2/WDR5/SIRT1/P2RX7/IGF1/EGF/PTH1R/IRS2/HRH1/HAS2/SORBS1	14
BP	GO:0046470	phosphatidylcholine metabolic process	14/2486	83/18670	0.2096	0.4605	0.361	PLA2G4C/FABP5/PLA2G5/APOC1/LPCAT4/LPCAT3/MFSD2A/PLA2G2A/ENPP2/SLC44A3/SLC44A2/PCYT1A/FABP3/LPCAT1	14
BP	GO:0007098	centrosome cycle	20/2486	124/18670	0.2104	0.4605	0.361	RBM14/PARD6G/CEP192/CHMP1B/MDM1/CEP135/HAUS8/ODF2/NIN/PLK1/C2CD3/UVRAG/USP33/HAUS2/NDE1/PARD6A/TMEM67/HEPACAM2/PARD6B/NEK2	20
BP	GO:0008637	apoptotic mitochondrial changes	20/2486	124/18670	0.2104	0.4605	0.361	CLU/PMAIP1/MFF/SLC25A5/JUN/FXN/NOL3/PINK1/MOAP1/BCL2L1/IGF1/YWHAZ/MMP9/BMF/IFI6/TP53BP2/TRIAP1/BAK1/PDCD5/CIDEB	20
BP	GO:0042107	cytokine metabolic process	20/2486	124/18670	0.2104	0.4605	0.361	INPP5D/INHBA/IRF1/TNF/BCL10/GHRL/ELANE/CD276/ZFP36/IRF4/CEBPE/TRAF6/HSPB1/RELA/KLF4/IL1B/WNT5A/TLR9/SPN/PTPRC	20
BP	GO:1904062	regulation of cation transmembrane transport	51/2486	342/18670	0.2107	0.4605	0.361	SRI/ANXA3/SCN1B/SLC9A3R1/PDPK1/STOM/ARF1/CNIH3/SNCA/TWIST1/DLG1/ATP1B2/TGFB1/PINK1/PHB2/FGF14/CACNB3/ADRA2A/DIAPH1/CX3CL1/DLG2/MIR21/PDE4B/EDN3/GRIA3/STAC/HECW2/GPR35/STAC2/UTRN/MMP9/AHNAK/RAMP3/FXYD1/APLNR/KCNA1/FKBP1B/THY1/TREM2/ANK2/SHISA8/FLNA/TLR9/RYR2/CAV1/LYN/DMD/ARC/EPHB2/CORO1A/SHANK3	51
BP	GO:0009048	dosage compensation by inactivation of X chromosome	4/2486	18/18670	0.2108	0.4605	0.361	XIST/YTHDC1/EIF1/RLIM	4
BP	GO:0009084	glutamine family amino acid biosynthetic process	4/2486	18/18670	0.2108	0.4605	0.361	SLC1A3/PYCR1/ASS1/CPS1	4
BP	GO:0010832	negative regulation of myotube differentiation	4/2486	18/18670	0.2108	0.4605	0.361	BDNF/TMEM119/BHLHE41/NOTCH1	4
BP	GO:0031293	membrane protein intracellular domain proteolysis	4/2486	18/18670	0.2108	0.4605	0.361	MBTPS1/TGFB1/TRAF6/RELA	4
BP	GO:0032693	negative regulation of interleukin-10 production	4/2486	18/18670	0.2108	0.4605	0.361	MMP8/FCGR2B/IL23R/PDCD1LG2	4
BP	GO:0036035	osteoclast development	4/2486	18/18670	0.2108	0.4605	0.361	LTF/FBXW7/NOTCH2/FBN1	4
BP	GO:0036148	phosphatidylglycerol acyl-chain remodeling	4/2486	18/18670	0.2108	0.4605	0.361	PLA2G5/LPCAT4/PLA2G2A/LPCAT1	4
BP	GO:0045683	negative regulation of epidermis development	4/2486	18/18670	0.2108	0.4605	0.361	HOXA7/HES1/SMO/NOTCH1	4
BP	GO:0060749	mammary gland alveolus development	4/2486	18/18670	0.2108	0.4605	0.361	PHB2/CCND1/EGF/TNFRSF11A	4
BP	GO:0061377	mammary gland lobule development	4/2486	18/18670	0.2108	0.4605	0.361	PHB2/CCND1/EGF/TNFRSF11A	4
BP	GO:0070233	negative regulation of T cell apoptotic process	4/2486	18/18670	0.2108	0.4605	0.361	ARG2/FADD/TSC22D3/DOCK8	4
BP	GO:0072079	nephron tubule formation	4/2486	18/18670	0.2108	0.4605	0.361	IRX2/IRX3/SIX1/SOX9	4
BP	GO:0097094	craniofacial suture morphogenesis	4/2486	18/18670	0.2108	0.4605	0.361	TWIST1/TGFB1/FOXN3/GLI3	4
BP	GO:0098877	neurotransmitter receptor transport to plasma membrane	4/2486	18/18670	0.2108	0.4605	0.361	GRIP1/GRIP2/GRASP/RAB8A	4
BP	GO:0098969	neurotransmitter receptor transport to postsynaptic membrane	4/2486	18/18670	0.2108	0.4605	0.361	GRIP1/GRIP2/GRASP/RAB8A	4
BP	GO:1902165	regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	4/2486	18/18670	0.2108	0.4605	0.361	MUC1/SIRT1/HNRNPK/TRIAP1	4
BP	GO:1901617	organic hydroxy compound biosynthetic process	41/2486	271/18670	0.2109	0.4607	0.3611	OSBP/MBTPS1/ASIP/OSBPL6/SNCA/TNF/HSD3B7/TGFB2/CD244/CH25H/LDHC/ERLIN1/NFYA/BMP2/SIRT1/GCH1/ACAT2/ERLIN2/PTS/OSBPL9/SLC24A5/PLCB2/IDI2/PTH1R/PLCB1/HRH1/PRKAG2/IL1B/PLCD4/REST/WNT5A/AKR1D1/NR4A2/PNMT/HMGCS1/HSD17B3/CYP39A1/PLTP/DKK3/GIPC1/NR1H4	41
BP	GO:0046637	regulation of alpha-beta T cell differentiation	11/2486	63/18670	0.2111	0.461	0.3613	SMAD7/CD83/MIR21/ZC3H12A/IRF4/NFKBIZ/HLX/IL23R/IL2/GLI3/RC3H1	11
BP	GO:0031330	negative regulation of cellular catabolic process	40/2486	264/18670	0.2115	0.4616	0.3618	SIRT2/RRAGA/GABARAPL2/SCFD1/HERC1/SNCA/DHX9/PINK1/SORL1/ZFP36/LARP1/MIR21/UBXN1/SMARCC1/APOC1/USP7/SMCR8/PML/CBFA2T3/HP/WAC/TIMP3/BMF/LRIG2/FOXK2/YBX1/MCL1/MTM1/NUPR1/LAPTM4B/CAMLG/TREM2/TIMP4/UBE2G2/HSP90AB1/RPS7/IL10RA/MTOR/TAF1/GIPC1	40
BP	GO:0098754	detoxification	21/2486	131/18670	0.2116	0.4616	0.3618	HBB/HBD/TNF/PRDX2/CYGB/PXDN/NXN/ABCG2/HBM/MIR21/MT2A/SESN2/LOXHD1/GCH1/GSTT1/NOS3/HP/GPX8/HBQ1/SOD3/NQO1	21
BP	GO:0031113	regulation of microtubule polymerization	9/2486	50/18670	0.2149	0.4683	0.367	NAV3/CLIP3/SNCA/FKBP4/NIN/MAP2/CDK5R1/CDH5/CLASP1	9
BP	GO:0072698	protein localization to microtubule cytoskeleton	9/2486	50/18670	0.2149	0.4683	0.367	APC/DIAPH1/CEP192/CRIPT/TTBK2/MID1/C2CD3/PARD6A/TTK	9
BP	GO:2000725	regulation of cardiac muscle cell differentiation	9/2486	50/18670	0.2149	0.4683	0.367	YY1/TGFB1/BMP2/IGF1/EFNB2/FRS2/MTOR/SOX6/PIN1	9
BP	GO:0015908	fatty acid transport	16/2486	97/18670	0.215	0.4683	0.367	LCN12/PPARG/CPT1C/CYP4F2/PLA2G5/ACE/BDKRB2/P2RX7/TNFRSF11A/IRS2/PRKAG2/MFSD2A/IL1B/PLA2G2A/SLCO2A1/FABP3	16
BP	GO:0048167	regulation of synaptic plasticity	29/2486	187/18670	0.215	0.4683	0.367	MME/ARF1/EIF2AK4/SNCA/SQSTM1/SCT/SSH1/CREB1/FGF14/STXBP1/CX3CL1/YTHDF1/NFATC4/NTRK2/PTN/HRH1/STX4/PPP3CB/SHISA8/FAM107A/RGS14/ARC/RAB8A/UNC13B/STAU1/EPHB2/GIPC1/PRRT2/SHANK3	29
BP	GO:0014912	negative regulation of smooth muscle cell migration	7/2486	37/18670	0.2153	0.4685	0.3672	TPM1/MIR21/SEMA6D/IGFBP5/MIR214/SLIT2/IGFBP3	7
BP	GO:0021587	cerebellum morphogenesis	7/2486	37/18670	0.2153	0.4685	0.3672	FAIM2/HERC1/LDB1/AGTPBP1/SMO/HSPA5/KIF14	7
BP	GO:0043243	positive regulation of protein complex disassembly	7/2486	37/18670	0.2153	0.4685	0.3672	EIF5A/TNF/IGF1R/SMCR8/FYCO1/NES/UVRAG	7
BP	GO:0072091	regulation of stem cell proliferation	12/2486	70/18670	0.2159	0.4695	0.368	VEGFC/TGFB1/ACE/CX3CL1/NANOG/PTN/SMO/NOTCH1/YAP1/GLI3/FBLN1/PTPRC	12
BP	GO:0006415	translational termination	17/2486	104/18670	0.217	0.4719	0.3698	EIF5A/MRPL36/MRPL44/MRPL48/MRPL15/MRPL20/MRPS28/MRPS14/MRPL18/MRPL13/MRPL21/MRPL17/MRPL54/N6AMT1/ABCE1/MRPL2/GFM2	17
BP	GO:0046651	lymphocyte proliferation	41/2486	272/18670	0.2181	0.474	0.3715	INPP5D/HLA-DPB1/ARG2/FADD/ARG1/IRF1/DLG1/TGFB1/IGFBP2/PRDX2/CD276/HES1/FCGR2B/TWSG1/MIR21/BTK/TRAF6/IL23R/P2RX7/IGF1/MSN/IRS2/PDCD1LG2/IL12A/IL2/TNFRSF14/GAPT/IL1B/FKBP1B/PPP3CB/GPNMB/VAV3/TLR9/CD300A/LYN/SPN/RC3H1/PTPRC/CORO1A/DOCK8/CD151	41
BP	GO:0098661	inorganic anion transmembrane transport	18/2486	111/18670	0.2187	0.4751	0.3724	SLC25A3/SLC4A1/TTYH2/SLC1A3/SLC20A1/SLC26A10/CLIC6/SLC12A8/SLC1A1/SLC26A6/FXYD1/ANKH/CLCN7/SLC26A8/SLC37A4/MTOR/GLRB/CLCN4	18
BP	GO:0006278	RNA-dependent DNA biosynthetic process	13/2486	77/18670	0.2197	0.4768	0.3737	RFC1/HSP90AA1/DCP2/TELO2/FBXO4/PKIB/CCT8/SMG6/HSP90AB1/MAPKAPK5/TNKS1BP1/NHP2/NEK2	13
BP	GO:0031397	negative regulation of protein ubiquitination	13/2486	77/18670	0.2197	0.4768	0.3737	TNFAIP3/SMAD7/DNAJA1/NXN/UBXN1/PRR7/DTX3L/CAMLG/CAV1/RPS7/MTOR/TAF1/TRIM44	13
BP	GO:0032481	positive regulation of type I interferon production	13/2486	77/18670	0.2197	0.4768	0.3737	XRCC6/EP300/NFKB2/IRF1/DHX9/IFI16/CREBBP/PQBP1/IFIH1/RELA/TLR9/SETD2/ZCCHC3	13
BP	GO:1901799	negative regulation of proteasomal protein catabolic process	10/2486	57/18670	0.2214	0.4803	0.3765	GABARAPL2/UBXN1/SMARCC1/USP7/WAC/MTM1/CAMLG/UBE2G2/HSP90AB1/GIPC1	10
BP	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	14/2486	84/18670	0.2228	0.4832	0.3787	SNCA/NOL3/HERPUD1/GAS6/RAF1/SFRP2/MMP9/WNT9A/AQP1/KLF4/SERPINB9/IFI6/TRIAP1/CRYAB	14
BP	GO:0035264	multicellular organism growth	23/2486	146/18670	0.2232	0.4832	0.3787	EP300/CSF1/NIPBL/CACNA2D2/TAF10/FXN/GHRL/CREB1/CDKN1C/ADARB1/SMPD3/WDR11/WWTR1/IGF1/FOXS1/SMO/FKBP8/WDTC1/PKDCC/STC2/MTOR/GHR/PALB2	23
BP	GO:0006261	DNA-dependent DNA replication	24/2486	153/18670	0.2236	0.4832	0.3787	MSH6/POLB/PRIM2/RFC1/POLE3/CDK9/ZRANB3/SAMHD1/FBXW7/HELB/POLE/WDR18/DDX11/SLBP/CDC45/DBF4/RNASEH1/RPAIN/RECQL4/POLG/GINS3/E2F8/ZNF830/MCM5	24
BP	GO:0009142	nucleoside triphosphate biosynthetic process	29/2486	188/18670	0.2238	0.4832	0.3787	SLC4A1/NUP93/TGFB1/PINK1/PFKFB2/LDHC/DHTKD1/FLCN/ZBTB7A/NUP50/NME5/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/VCP/RAE1/NUP188/NUP160/NUP54/NUP214/NUP155/FOXK2/NUPR1/SLC2A6/PRKAG2/TREM2/PFKP	29
BP	GO:1901292	nucleoside phosphate catabolic process	29/2486	188/18670	0.2238	0.4832	0.3787	NUDT15/SLC4A1/NUP93/TDG/PFKFB2/PDE2A/SAMHD1/DHTKD1/ZBTB7A/PDE4B/NUP50/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/VCP/RAE1/NUP188/NUP160/NUP54/NUP214/NUP155/FOXK2/NUPR1/SLC2A6/PRKAG2/PDE1A/PFKP	29
BP	GO:0006941	striated muscle contraction	27/2486	174/18670	0.224	0.4832	0.3787	SRI/SCN1B/ARG2/MYL4/SMAD7/DLG1/TPM1/GJA5/ZC3H12A/PDE4B/SGCD/JUP/KCND3/STAC/STC1/STAC2/KCNA5/NUP155/KCNJ8/RCSD1/FKBP1B/ANK2/FLNA/RYR2/CAV1/MTOR/DMD	27
BP	GO:0046488	phosphatidylinositol metabolic process	27/2486	174/18670	0.224	0.4832	0.3787	SOCS7/TTC7B/PLA2G4C/BMX/INPP5D/ARF1/PTPN13/PIGH/PLEKHA4/PLEKHA3/PLEKHA2/PLA2G5/PIGX/PIGA/PLCB1/MTMR14/PIK3CD/PDGFRB/MTM1/PLA2G2A/PLCD4/MTMR12/PIGY/INPP5F/PIGL/MTMR7/MTMR4	27
BP	GO:0002082	regulation of oxidative phosphorylation	6/2486	31/18670	0.2243	0.4832	0.3787	SLC25A33/SNCA/PINK1/VCP/COX7A1/NUPR1	6
BP	GO:0002888	positive regulation of myeloid leukocyte mediated immunity	6/2486	31/18670	0.2243	0.4832	0.3787	CD177/ARG1/STXBP1/DDX21/BTK/STX4	6
BP	GO:0006658	phosphatidylserine metabolic process	6/2486	31/18670	0.2243	0.4832	0.3787	PTDSS1/PLA2G5/LPCAT4/SERINC3/LPCAT3/PLA2G2A	6
BP	GO:0007202	activation of phospholipase C activity	6/2486	31/18670	0.2243	0.4832	0.3787	ARHGAP6/BDNF/P2RY12/EGFR/NTRK2/PLCB2	6
BP	GO:0010719	negative regulation of epithelial to mesenchymal transition	6/2486	31/18670	0.2243	0.4832	0.3787	TBX5/SMAD7/PPP2CA/TGFB2/SFRP2/SFRP1	6
BP	GO:0040020	regulation of meiotic nuclear division	6/2486	31/18670	0.2243	0.4832	0.3787	SIRT2/GPR3/PLCB1/WNT5A/MSX1/TTK	6
BP	GO:0043304	regulation of mast cell degranulation	6/2486	31/18670	0.2243	0.4832	0.3787	PDPK1/STXBP1/C12orf4/IL13RA2/CD300A/LYN	6
BP	GO:0043457	regulation of cellular respiration	6/2486	31/18670	0.2243	0.4832	0.3787	SNCA/PINK1/FLCN/CBFA2T3/VCP/IDE	6
BP	GO:0045648	positive regulation of erythrocyte differentiation	6/2486	31/18670	0.2243	0.4832	0.3787	INPP5D/INHBA/GATA1/TRIM58/TAL1/ACVR2A	6
BP	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity	6/2486	31/18670	0.2243	0.4832	0.3787	CCND1/EGFR/CCNT2/CCNYL2/CCNY/CDK5R1	6
BP	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	6/2486	31/18670	0.2243	0.4832	0.3787	LPAR6/GPR4/LPAR4/GPR35/AGTR1/P2RY8	6
BP	GO:0090659	walking behavior	6/2486	31/18670	0.2243	0.4832	0.3787	FXN/TRH/CLN8/DMRT3/UCHL1/GLRB	6
BP	GO:0099625	ventricular cardiac muscle cell membrane repolarization	6/2486	31/18670	0.2243	0.4832	0.3787	SCN1B/DLG1/GJA5/KCND3/KCNJ8/ANK2	6
BP	GO:2000781	positive regulation of double-strand break repair	6/2486	31/18670	0.2243	0.4832	0.3787	PARP3/FUS/PARP9/DDX11/DTX3L/MGMT	6
BP	GO:0007019	microtubule depolymerization	8/2486	44/18670	0.2251	0.4841	0.3794	FGF13/NAV3/APC/CLASP2/TTBK2/MID1/KIF2C/CLASP1	8
BP	GO:0044060	regulation of endocrine process	8/2486	44/18670	0.2251	0.4841	0.3794	INHBA/GHRL/RAB11FIP1/RAB11FIP5/GJA5/AGTR1/C1QTNF1/IL1B	8
BP	GO:0090382	phagosome maturation	8/2486	44/18670	0.2251	0.4841	0.3794	ATP6V1E1/ATP6V0A2/ATP6V1G3/P2RX7/RAB7B/UNC13B/CORO1A/SYT11	8
BP	GO:1903214	regulation of protein targeting to mitochondrion	8/2486	44/18670	0.2251	0.4841	0.3794	ABLIM3/BAG4/PINK1/ARIH2/FBXW7/FZD5/UBE2D3/PDCD5	8
BP	GO:1900449	regulation of glutamate receptor signaling pathway	11/2486	64/18670	0.2265	0.487	0.3817	ANXA3/CNIH3/DLG1/PINK1/CX3CL1/DLG2/GRIA3/SHISA8/ARC/EPHB2/SHANK3	11
BP	GO:0001824	blastocyst development	16/2486	98/18670	0.2273	0.4883	0.3827	PELO/BCOR/LPAR6/TM4SF1/SP3/EMG1/SKIL/IGF1/MFNG/HCFC1/BYSL/CMTM3/PALB2/JUNB/NEK2/ZNF830	16
BP	GO:0002042	cell migration involved in sprouting angiogenesis	16/2486	98/18670	0.2273	0.4883	0.3827	NRP1/FBXW7/MMRN2/CARD10/EPHB4/RHOJ/SRPX2/EFNB2/MEOX2/KLF4/NOTCH1/CLEC14A/PDCD10/MAP3K3/SLIT2/KDR	16
BP	GO:0031124	mRNA 3'-end processing	16/2486	98/18670	0.2273	0.4883	0.3827	CPSF7/SRRM1/PAPOLA/SARNP/CDK9/THOC2/RPRD2/U2AF1L4/MTPAP/SLBP/U2AF1/PABPN1/CPEB1/PCF11/POLR2D/BARD1	16
BP	GO:0002449	lymphocyte mediated immunity	52/2486	352/18670	0.2291	0.4919	0.3855	CLU/FAM49B/C1QB/C1QA/CD1C/C1QC/MSH6/INPP5D/FADD/PARP3/ARG1/LYST/TNF/SMAD7/DLG1/BCL10/IL1R1/TGFB1/C2/FBXO38/FCGR2B/CD1B/EXO1/BTK/SERPING1/EXOSC3/TRAF6/IL23R/VAV1/BATF/P2RX7/HLA-B/CEACAM1/C1RL/IL13RA2/IL12A/IL2/C1R/SERPINB9/EMP2/GAPT/IL1B/PPP3CB/FZD5/POU2F2/C1S/CFI/PTPRC/CORO1A/RSAD2/HLA-A/RNF8	52
BP	GO:0031109	microtubule polymerization or depolymerization	18/2486	112/18670	0.2303	0.4943	0.3874	FGF13/NAV3/CLIP3/APC/SNCA/FKBP4/CLASP2/CEP192/NIN/MAP2/TTBK2/MID1/KIF2C/CDK5R1/NDE1/CDH5/CLASP1/CRYAB	18
BP	GO:0044786	cell cycle DNA replication	12/2486	71/18670	0.2305	0.4947	0.3877	MSH6/PRIM2/RFC1/POLE3/FBXW7/POLE/SLBP/CDC45/DBF4/E2F8/ZNF830/MCM5	12
BP	GO:0043624	cellular protein complex disassembly	33/2486	217/18670	0.2308	0.4952	0.3881	EPS8/FGF13/EIF5A/TMOD1/MRPL36/NAV3/APC/MRPL44/MRPL48/CLASP2/MRPL15/MRPL20/ASPH/AVIL/MRPS28/MRPS14/TTBK2/LMOD1/PLEKHH2/MID1/MRPL18/KIF2C/CAPZA1/NES/MRPL13/MRPL21/MRPL17/CLASP1/MRPL54/N6AMT1/ABCE1/MRPL2/GFM2	33
BP	GO:0006694	steroid biosynthetic process	30/2486	196/18670	0.2323	0.4963	0.389	OSBP/CYP11A1/MBTPS1/OSBPL6/PBX1/TNF/HSD3B7/CH25H/ERLIN1/NFYA/BMP2/CYP21A2/SIRT1/HSD11B2/ACAT2/ERLIN2/HSD17B14/OSBPL9/HSD11B1/IDI2/HSD17B1/PRKAG2/IL1B/REST/AKR1D1/HMGCS1/HSD17B3/CYP39A1/DKK3/NR1H4	30
BP	GO:0010389	regulation of G2/M transition of mitotic cell cycle	30/2486	196/18670	0.2323	0.4963	0.389	PSMD14/PSMD12/SYF2/PBX1/PSMD7/PSMB5/CCND1/HSP90AA1/CEP192/MIR21/TPX2/CEP135/FOXN3/HAUS8/ODF2/PSMB7/PLK1/PSMD1/PSMD9/HAUS2/NDE1/SSNA1/CLASP1/PSME1/PRKAR2B/SIN3A/KIF14/NEK2/CUL1/ZNF830	30
BP	GO:0045668	negative regulation of osteoblast differentiation	9/2486	51/18670	0.2324	0.4963	0.389	TNF/TWIST1/TWSG1/TWIST2/SEMA4D/IGFBP5/NOTCH1/SFRP1/LRP5	9
BP	GO:0048260	positive regulation of receptor-mediated endocytosis	9/2486	51/18670	0.2324	0.4963	0.389	CLU/NTF3/DAB2/EGF/HNRNPK/CBL/SFRP4/CCL21/MAGI2	9
BP	GO:0090102	cochlea development	9/2486	51/18670	0.2324	0.4963	0.389	PVALB/HES1/SOBP/SIX1/KCNK3/SOX9/CTHRC1/WNT5A/TBX1	9
BP	GO:0001508	action potential	21/2486	133/18670	0.2327	0.4963	0.389	SRI/NRCAM/SCN1B/FGF13/DLG1/CACNB3/GJA5/JUP/KCND3/NTRK2/GPR35/KCNA5/NUP155/KCNJ8/KCNA1/FKBP1B/ANK2/FLNA/RYR2/CAV1/DMD	21
BP	GO:0002335	mature B cell differentiation	5/2486	25/18670	0.2331	0.4963	0.389	FCGR2B/MFNG/NOTCH2/POU2F2/DOCK11	5
BP	GO:0002719	negative regulation of cytokine production involved in immune response	5/2486	25/18670	0.2331	0.4963	0.389	ARG1/TNF/SMAD7/TGFB2/TGFB1	5
BP	GO:0014829	vascular smooth muscle contraction	5/2486	25/18670	0.2331	0.4963	0.389	EDNRB/MIR21/GRIP2/EDN3/ACTA2	5
BP	GO:0031069	hair follicle morphogenesis	5/2486	25/18670	0.2331	0.4963	0.389	TGFB2/IGFBP5/SMO/NOTCH1/INTU	5
BP	GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway	5/2486	25/18670	0.2331	0.4963	0.389	TNFAIP3/LTF/PRDX2/CX3CL1/TRAF6	5
BP	GO:0032104	regulation of response to extracellular stimulus	5/2486	25/18670	0.2331	0.4963	0.389	GHRL/KANK2/TRIM24/NENF/MTOR	5
BP	GO:0032107	regulation of response to nutrient levels	5/2486	25/18670	0.2331	0.4963	0.389	GHRL/KANK2/TRIM24/NENF/MTOR	5
BP	GO:0046755	viral budding	5/2486	25/18670	0.2331	0.4963	0.389	VPS37A/CHMP6/CHMP1B/VPS37B/LRSAM1	5
BP	GO:0046856	phosphatidylinositol dephosphorylation	5/2486	25/18670	0.2331	0.4963	0.389	INPP5D/MTM1/INPP5F/MTMR7/MTMR4	5
BP	GO:0050927	positive regulation of positive chemotaxis	5/2486	25/18670	0.2331	0.4963	0.389	NTF3/VEGFC/CXCL12/KDR/ITGA2	5
BP	GO:0051654	establishment of mitochondrion localization	5/2486	25/18670	0.2331	0.4963	0.389	TRAK1/ACTR10/UCHL1/WASF1/MARK1	5
BP	GO:0060330	regulation of response to interferon-gamma	5/2486	25/18670	0.2331	0.4963	0.389	PPARG/ARG1/PARP9/JAK1/HSP90AB1	5
BP	GO:0060334	regulation of interferon-gamma-mediated signaling pathway	5/2486	25/18670	0.2331	0.4963	0.389	PPARG/ARG1/PARP9/JAK1/HSP90AB1	5
BP	GO:0072202	cell differentiation involved in metanephros development	5/2486	25/18670	0.2331	0.4963	0.389	WWTR1/SMO/CD34/YAP1/SIX2	5
BP	GO:0072273	metanephric nephron morphogenesis	5/2486	25/18670	0.2331	0.4963	0.389	HES1/SMO/PDGFRB/SOX9/SIX2	5
BP	GO:1905809	negative regulation of synapse organization	5/2486	25/18670	0.2331	0.4963	0.389	NFATC4/PTN/WNT5A/SLIT1/ARHGEF15	5
BP	GO:0006040	amino sugar metabolic process	7/2486	38/18670	0.2359	0.5003	0.3921	CHIT1/CHST1/SLC35A3/CMAS/CHST3/GFPT2/ST6GAL1	7
BP	GO:0006656	phosphatidylcholine biosynthetic process	7/2486	38/18670	0.2359	0.5003	0.3921	FABP5/MFSD2A/SLC44A3/SLC44A2/PCYT1A/FABP3/LPCAT1	7
BP	GO:0007340	acrosome reaction	7/2486	38/18670	0.2359	0.5003	0.3921	ADCY3/STX2/STXBP1/PLCB1/PLCD4/GLRB/UNC13B	7
BP	GO:0016572	histone phosphorylation	7/2486	38/18670	0.2359	0.5003	0.3921	AKAP8L/PRKCB/TWIST1/CDK9/IL1B/AKAP8/RPS6KA5	7
BP	GO:0032350	regulation of hormone metabolic process	7/2486	38/18670	0.2359	0.5003	0.3921	TNF/BMP2/GNB3/IL1B/REST/STC2/DKK3	7
BP	GO:0048246	macrophage chemotaxis	7/2486	38/18670	0.2359	0.5003	0.3921	EDNRB/CSF1/AKIRIN1/CX3CL1/RARRES2/MTUS1/MST1	7
BP	GO:0050716	positive regulation of interleukin-1 secretion	7/2486	38/18670	0.2359	0.5003	0.3921	ORM1/LPL/P2RX7/FZD5/NLRP1/WNT5A/NLRP7	7
BP	GO:0060416	response to growth hormone	7/2486	38/18670	0.2359	0.5003	0.3921	GHRL/PHEX/ASS1/IGFBP5/CPS1/LYN/GHR	7
BP	GO:0086091	regulation of heart rate by cardiac conduction	7/2486	38/18670	0.2359	0.5003	0.3921	SCN1B/GJA5/JUP/KCND3/KCNA5/ANK2/CAV1	7
BP	GO:0097352	autophagosome maturation	7/2486	38/18670	0.2359	0.5003	0.3921	GABARAPL2/MAP1LC3A/TECPR1/SMCR8/FYCO1/VCP/UVRAG	7
BP	GO:1904037	positive regulation of epithelial cell apoptotic process	7/2486	38/18670	0.2359	0.5003	0.3921	ITGA4/EIF2S1/COL18A1/ECSCR/SFRP4/CD248/CAPN10	7
BP	GO:0009798	axis specification	14/2486	85/18670	0.2363	0.5007	0.3924	BCOR/LDB1/PCSK6/DDIT3/STC1/HOXD8/SMO/FRS2/NOTCH1/SFRP1/C2CD3/FZD5/WNT5A/SIX2	14
BP	GO:1904705	regulation of vascular smooth muscle cell proliferation	14/2486	85/18670	0.2363	0.5007	0.3924	PPARG/MEF2D/HPGD/TNF/JUN/TPM1/ERN1/MIR21/MAP3K5/IGF1/MMP9/IGFBP5/MIR214/FOXJ2	14
BP	GO:1990874	vascular smooth muscle cell proliferation	14/2486	85/18670	0.2363	0.5007	0.3924	PPARG/MEF2D/HPGD/TNF/JUN/TPM1/ERN1/MIR21/MAP3K5/IGF1/MMP9/IGFBP5/MIR214/FOXJ2	14
BP	GO:0050890	cognition	44/2486	296/18670	0.2373	0.5026	0.394	ADCY3/NTAN1/NTF3/FGF13/MME/CLDN5/EP300/BDNF/NIPBL/EIF2AK4/B4GALT2/TNF/JUN/CUX2/CREB1/SHROOM4/CLN8/FOS/YTHDF1/NFATC4/EGFR/NTRK2/MEIS2/SOBP/KCNK10/ITGA3/PTN/PLCB1/CBR3/HRH1/BTG2/PPP3CB/OXTR/FAM107A/NLGN4X/MTOR/RGS14/ARC/TUSC3/PRKAR2B/EPHB2/SLC6A1/SHANK3/LHX8	44
BP	GO:0032722	positive regulation of chemokine production	10/2486	58/18670	0.2379	0.5036	0.3947	MBP/TNF/TWIST1/LPL/IL1B/IL33/WNT5A/TLR9/POSTN/ADCYAP1	10
BP	GO:1903749	positive regulation of establishment of protein localization to mitochondrion	10/2486	58/18670	0.2379	0.5036	0.3947	ABLIM3/PMAIP1/PINK1/ARIH2/FBXW7/YWHAZ/FZD5/UBE2D3/TP53BP2/PDCD5	10
BP	GO:0019395	fatty acid oxidation	16/2486	99/18670	0.2399	0.5044	0.3954	ACAD10/PPARG/CPT1C/TWIST1/CYGB/ETFDH/SESN2/ACAT2/ADIPOR2/IRS2/PRKAG2/ETFA/CRAT/MTOR/PDK4/FABP3	16
BP	GO:0001832	blastocyst growth	4/2486	19/18670	0.2409	0.5044	0.3954	PELO/IGF1/PALB2/ZNF830	4
BP	GO:0002313	mature B cell differentiation involved in immune response	4/2486	19/18670	0.2409	0.5044	0.3954	FCGR2B/MFNG/NOTCH2/DOCK11	4
BP	GO:0002922	positive regulation of humoral immune response	4/2486	19/18670	0.2409	0.5044	0.3954	TNF/FCGR2B/IL1B/PTPRC	4
BP	GO:0010888	negative regulation of lipid storage	4/2486	19/18670	0.2409	0.5044	0.3954	ITGB3/PPARG/NFKBIA/TNF	4
BP	GO:0021533	cell differentiation in hindbrain	4/2486	19/18670	0.2409	0.5044	0.3954	FAIM2/HERC1/LDB1/AGTPBP1	4
BP	GO:0032026	response to magnesium ion	4/2486	19/18670	0.2409	0.5044	0.3954	SNCA/CCND1/SMPD3/KCNA1	4
BP	GO:0032288	myelin assembly	4/2486	19/18670	0.2409	0.5044	0.3954	MPP5/CD9/GPC1/ANK2	4
BP	GO:0032303	regulation of icosanoid secretion	4/2486	19/18670	0.2409	0.5044	0.3954	CYP4F2/P2RX7/TNFRSF11A/IL1B	4
BP	GO:0033189	response to vitamin A	4/2486	19/18670	0.2409	0.5044	0.3954	PPARG/ARG1/CYP26B1/ALDH1A2	4
BP	GO:0034138	toll-like receptor 3 signaling pathway	4/2486	19/18670	0.2409	0.5044	0.3954	TNFAIP3/FADD/COLEC12/CAV1	4
BP	GO:0035269	protein O-linked mannosylation	4/2486	19/18670	0.2409	0.5044	0.3954	SDF2L1/FKRP/TMTC4/SDF2	4
BP	GO:0045063	T-helper 1 cell differentiation	4/2486	19/18670	0.2409	0.5044	0.3954	HLX/TMEM98/MTOR/SPN	4
BP	GO:0045076	regulation of interleukin-2 biosynthetic process	4/2486	19/18670	0.2409	0.5044	0.3954	ZFP36/IRF4/IL1B/PTPRC	4
BP	GO:0060252	positive regulation of glial cell proliferation	4/2486	19/18670	0.2409	0.5044	0.3954	TNF/IL1B/MTOR/LYN	4
BP	GO:0060716	labyrinthine layer blood vessel development	4/2486	19/18670	0.2409	0.5044	0.3954	HES1/VASH1/FZD5/JUNB	4
BP	GO:0060973	cell migration involved in heart development	4/2486	19/18670	0.2409	0.5044	0.3954	TBX5/TWIST1/PDGFRB/NOTCH1	4
BP	GO:0098911	regulation of ventricular cardiac muscle cell action potential	4/2486	19/18670	0.2409	0.5044	0.3954	DLG1/JUP/RYR2/CAV1	4
BP	GO:1902074	response to salt	4/2486	19/18670	0.2409	0.5044	0.3954	TGFB1/ZC3H12A/PHEX/HSPA5	4
BP	GO:1903540	establishment of protein localization to postsynaptic membrane	4/2486	19/18670	0.2409	0.5044	0.3954	GRIP1/GRIP2/GRASP/RAB8A	4
BP	GO:1903798	regulation of production of miRNAs involved in gene silencing by miRNA	4/2486	19/18670	0.2409	0.5044	0.3954	TGFB1/ZC3H12A/EGFR/ZC3H10	4
BP	GO:1904683	regulation of metalloendopeptidase activity	4/2486	19/18670	0.2409	0.5044	0.3954	MBP/SORL1/MIR21/TIMP3	4
BP	GO:1905288	vascular associated smooth muscle cell apoptotic process	4/2486	19/18670	0.2409	0.5044	0.3954	PPARG/MIR21/IGF1/STK4	4
BP	GO:1905459	regulation of vascular associated smooth muscle cell apoptotic process	4/2486	19/18670	0.2409	0.5044	0.3954	PPARG/MIR21/IGF1/STK4	4
BP	GO:2000010	positive regulation of protein localization to cell surface	4/2486	19/18670	0.2409	0.5044	0.3954	TNF/LRIG2/STX4/HSP90AB1	4
BP	GO:2000251	positive regulation of actin cytoskeleton reorganization	4/2486	19/18670	0.2409	0.5044	0.3954	NTF3/NRP1/TEK/HCLS1	4
BP	GO:0009156	ribonucleoside monophosphate biosynthetic process	30/2486	197/18670	0.2412	0.5044	0.3954	SLC4A1/NUP93/TGFB1/PINK1/PFKFB2/LDHC/DHTKD1/FLCN/ZBTB7A/NUP50/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/VCP/RAE1/NUP188/NUP160/NUP54/NUP214/NUP155/FOXK2/AMPD2/NUPR1/SLC2A6/PRKAG2/TREM2/PFAS/PFKP	30
BP	GO:0014823	response to activity	11/2486	65/18670	0.2422	0.5044	0.3954	TOMM20/CREB1/KDM6B/PTN/COL4A2/CBL/ANGPT2/RYR2/MTOR/POSTN/ITGA2	11
BP	GO:0048663	neuron fate commitment	11/2486	65/18670	0.2422	0.5044	0.3954	JAG2/DMRT3/HOXC10/SATB2/SIX1/PRRX1/POU4F1/NOTCH1/GLI3/OLIG1/NOTCH3	11
BP	GO:0060968	regulation of gene silencing	24/2486	155/18670	0.2436	0.5044	0.3954	PPARG/NUP93/FXR1/DHX9/TGFB1/ZFP36/ZC3H12A/NUP50/SIRT1/EGFR/POLR2G/NEAT1/NUP153/NUP210/CDC45/RAE1/NUP188/NUP160/NUP54/NUP214/ZC3H10/NUP155/POLR2D/SIN3A	24
BP	GO:0014014	negative regulation of gliogenesis	8/2486	45/18670	0.2442	0.5044	0.3954	SIRT2/DUSP10/DAAM2/HES1/PTN/TMEM98/NOTCH1/ADCYAP1	8
BP	GO:0032309	icosanoid secretion	8/2486	45/18670	0.2442	0.5044	0.3954	CYP4F2/PLA2G5/ACE/BDKRB2/P2RX7/TNFRSF11A/IL1B/PLA2G2A	8
BP	GO:0032456	endocytic recycling	8/2486	45/18670	0.2442	0.5044	0.3954	VPS53/RAB13/RAB11FIP4/SORL1/EHD2/ACAP2/INPP5F/CCDC93	8
BP	GO:0071827	plasma lipoprotein particle organization	8/2486	45/18670	0.2442	0.5044	0.3954	ARF1/LPL/APOC1/GPIHBP1/AGTR1/PLAGL2/PLA2G2A/PLTP	8
BP	GO:0001765	membrane raft assembly	3/2486	13/18670	0.2451	0.5044	0.3954	CAV2/EMP2/CAV1	3
BP	GO:0001845	phagolysosome assembly	3/2486	13/18670	0.2451	0.5044	0.3954	P2RX7/RAB7B/CORO1A	3
BP	GO:0001867	complement activation, lectin pathway	3/2486	13/18670	0.2451	0.5044	0.3954	SCARA3/SERPING1/A2M	3
BP	GO:0002281	macrophage activation involved in immune response	3/2486	13/18670	0.2451	0.5044	0.3954	SUCNR1/IL33/TREM2	3
BP	GO:0002679	respiratory burst involved in defense response	3/2486	13/18670	0.2451	0.5044	0.3954	DUSP10/PRDX2/PIK3CD	3
BP	GO:0002829	negative regulation of type 2 immune response	3/2486	13/18670	0.2451	0.5044	0.3954	ARG2/ARG1/HLX	3
BP	GO:0002864	regulation of acute inflammatory response to antigenic stimulus	3/2486	13/18670	0.2451	0.5044	0.3954	FCGR2B/BTK/ADCYAP1	3
BP	GO:0003084	positive regulation of systemic arterial blood pressure	3/2486	13/18670	0.2451	0.5044	0.3954	ACE/HSD11B2/NR2F2	3
BP	GO:0003157	endocardium development	3/2486	13/18670	0.2451	0.5044	0.3954	ACVR1/STK4/NOTCH1	3
BP	GO:0003306	Wnt signaling pathway involved in heart development	3/2486	13/18670	0.2451	0.5044	0.3954	BMP2/WNT5A/ALPK2	3
BP	GO:0006707	cholesterol catabolic process	3/2486	13/18670	0.2451	0.5044	0.3954	HSD3B7/AKR1D1/CYP39A1	3
BP	GO:0007183	SMAD protein complex assembly	3/2486	13/18670	0.2451	0.5044	0.3954	TGFB1/SMAD1/PPM1A	3
BP	GO:0009635	response to herbicide	3/2486	13/18670	0.2451	0.5044	0.3954	ARG1/LCN2/ZC3H12A	3
BP	GO:0010745	negative regulation of macrophage derived foam cell differentiation	3/2486	13/18670	0.2451	0.5044	0.3954	ITGB3/PPARG/NFKBIA	3
BP	GO:0010838	positive regulation of keratinocyte proliferation	3/2486	13/18670	0.2451	0.5044	0.3954	MIR21/HAS2/NOTCH2	3
BP	GO:0010839	negative regulation of keratinocyte proliferation	3/2486	13/18670	0.2451	0.5044	0.3954	CD109/EFNB2/INTU	3
BP	GO:0014842	regulation of skeletal muscle satellite cell proliferation	3/2486	13/18670	0.2451	0.5044	0.3954	AKIRIN1/SIX1/SIX5	3
BP	GO:0016127	sterol catabolic process	3/2486	13/18670	0.2451	0.5044	0.3954	HSD3B7/AKR1D1/CYP39A1	3
BP	GO:0019896	axonal transport of mitochondrion	3/2486	13/18670	0.2451	0.5044	0.3954	TRAK1/ACTR10/UCHL1	3
BP	GO:0021554	optic nerve development	3/2486	13/18670	0.2451	0.5044	0.3954	NAV2/GLI3/EPHB2	3
BP	GO:0021681	cerebellar granular layer development	3/2486	13/18670	0.2451	0.5044	0.3954	FAIM2/TTBK2/KIF14	3
BP	GO:0021978	telencephalon regionalization	3/2486	13/18670	0.2451	0.5044	0.3954	TRA2B/BMP2/EMX2	3
BP	GO:0030205	dermatan sulfate metabolic process	3/2486	13/18670	0.2451	0.5044	0.3954	BGN/DCN/CSPG4	3
BP	GO:0031274	positive regulation of pseudopodium assembly	3/2486	13/18670	0.2451	0.5044	0.3954	APC/CCL21/CDC42EP5	3
BP	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway	3/2486	13/18670	0.2451	0.5044	0.3954	TNFAIP3/LTF/PRDX2	3
BP	GO:0031953	negative regulation of protein autophosphorylation	3/2486	13/18670	0.2451	0.5044	0.3954	JUN/CAV1/PTPRC	3
BP	GO:0032823	regulation of natural killer cell differentiation	3/2486	13/18670	0.2451	0.5044	0.3954	PGLYRP1/GAS6/AXL	3
BP	GO:0033004	negative regulation of mast cell activation	3/2486	13/18670	0.2451	0.5044	0.3954	IL13RA2/CD300LF/CD300A	3
BP	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway	3/2486	13/18670	0.2451	0.5044	0.3954	PHB2/KANK2/CNOT1	3
BP	GO:0033605	positive regulation of catecholamine secretion	3/2486	13/18670	0.2451	0.5044	0.3954	PINK1/CXCL12/OXTR	3
BP	GO:0034214	protein hexamerization	3/2486	13/18670	0.2451	0.5044	0.3954	LRRC8A/VCP/MAT2A	3
BP	GO:0035589	G protein-coupled purinergic nucleotide receptor signaling pathway	3/2486	13/18670	0.2451	0.5044	0.3954	P2RY12/P2RY2/P2RY8	3
BP	GO:0035627	ceramide transport	3/2486	13/18670	0.2451	0.5044	0.3954	PLEKHA3/GLTP/PLTP	3
BP	GO:0042635	positive regulation of hair cycle	3/2486	13/18670	0.2451	0.5044	0.3954	TNF/TGFB2/WNT5A	3
BP	GO:0043201	response to leucine	3/2486	13/18670	0.2451	0.5044	0.3954	SESN2/SESN3/MTOR	3
BP	GO:0045086	positive regulation of interleukin-2 biosynthetic process	3/2486	13/18670	0.2451	0.5044	0.3954	IRF4/IL1B/PTPRC	3
BP	GO:0048711	positive regulation of astrocyte differentiation	3/2486	13/18670	0.2451	0.5044	0.3954	HES1/BMP2/NOTCH1	3
BP	GO:0060100	positive regulation of phagocytosis, engulfment	3/2486	13/18670	0.2451	0.5044	0.3954	PPARG/TREM2/ITGA2	3
BP	GO:0060123	regulation of growth hormone secretion	3/2486	13/18670	0.2451	0.5044	0.3954	GHRL/SERP1/ADCYAP1	3
BP	GO:0060340	positive regulation of type I interferon-mediated signaling pathway	3/2486	13/18670	0.2451	0.5044	0.3954	FADD/TRIM6/WNT5A	3
BP	GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	3/2486	13/18670	0.2451	0.5044	0.3954	TNFAIP3/NFKBIA/RELA	3
BP	GO:0071352	cellular response to interleukin-2	3/2486	13/18670	0.2451	0.5044	0.3954	JAK1/IL2/CDC5L	3
BP	GO:0090179	planar cell polarity pathway involved in neural tube closure	3/2486	13/18670	0.2451	0.5044	0.3954	SFRP2/SFRP1/WNT5A	3
BP	GO:0097152	mesenchymal cell apoptotic process	3/2486	13/18670	0.2451	0.5044	0.3954	SOX9/MSX1/TBX1	3
BP	GO:0098712	L-glutamate import across plasma membrane	3/2486	13/18670	0.2451	0.5044	0.3954	SLC1A3/CLN8/SLC1A1	3
BP	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading	3/2486	13/18670	0.2451	0.5044	0.3954	AP1AR/FBLN1/POSTN	3
BP	GO:1902285	semaphorin-plexin signaling pathway involved in neuron projection guidance	3/2486	13/18670	0.2451	0.5044	0.3954	PLXNA3/NRP1/PLXNA1	3
BP	GO:1902713	regulation of interferon-gamma secretion	3/2486	13/18670	0.2451	0.5044	0.3954	CD244/ZC3H12A/NR1H4	3
BP	GO:1905155	positive regulation of membrane invagination	3/2486	13/18670	0.2451	0.5044	0.3954	PPARG/TREM2/ITGA2	3
BP	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining	3/2486	13/18670	0.2451	0.5044	0.3954	PARP3/PARP9/DTX3L	3
BP	GO:0002532	production of molecular mediator involved in inflammatory response	12/2486	72/18670	0.2456	0.505	0.3958	C5orf30/ADCY7/DUSP10/PRDX2/MIR21/ZC3H12A/BTK/SNAP23/IL17D/LYN/PER1/NLRP7	12
BP	GO:1903747	regulation of establishment of protein localization to mitochondrion	12/2486	72/18670	0.2456	0.505	0.3958	ABLIM3/PMAIP1/BAG4/DNAJA1/PINK1/ARIH2/FBXW7/YWHAZ/FZD5/UBE2D3/TP53BP2/PDCD5	12
BP	GO:0032814	regulation of natural killer cell activation	6/2486	32/18670	0.2474	0.5076	0.3978	PGLYRP1/GAS6/RHBDD3/IL23R/IL12A/AXL	6
BP	GO:0033006	regulation of mast cell activation involved in immune response	6/2486	32/18670	0.2474	0.5076	0.3978	PDPK1/STXBP1/C12orf4/IL13RA2/CD300A/LYN	6
BP	GO:0042311	vasodilation	6/2486	32/18670	0.2474	0.5076	0.3978	EDNRB/BDKRB2/GCH1/NOS3/KCNMA1/CPS1	6
BP	GO:0042491	inner ear auditory receptor cell differentiation	6/2486	32/18670	0.2474	0.5076	0.3978	SLC9A3R1/MCOLN3/HES1/JAG2/SEC24B/NOTCH1	6
BP	GO:0045907	positive regulation of vasoconstriction	6/2486	32/18670	0.2474	0.5076	0.3978	GJA5/MIR21/EGFR/HRH1/OXTR/CAV1	6
BP	GO:0045922	negative regulation of fatty acid metabolic process	6/2486	32/18670	0.2474	0.5076	0.3978	ERLIN1/APOC1/SIRT1/ERLIN2/CEACAM1/WDTC1	6
BP	GO:0099623	regulation of cardiac muscle cell membrane repolarization	6/2486	32/18670	0.2474	0.5076	0.3978	SCN1B/DLG1/GJA5/KCNA5/ANK2/FLNA	6
BP	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	13/2486	79/18670	0.2482	0.509	0.3989	PSMD14/PSMD12/ITGB5/PSMD7/PDIA3/PSMB5/HLA-B/PSMB7/SNAP23/PSMD1/PSMD9/PSME1/HLA-A	13
BP	GO:0015850	organic hydroxy compound transport	39/2486	262/18670	0.2502	0.5118	0.4011	CLU/ITGB3/OSBP/SLC18A1/GRAMD1B/PPARG/OSBPL6/NFKBIA/SNCA/GHRL/OSBP2/PINK1/SLC10A2/ADRA2A/P2RY12/MSR1/APOC1/SIRT1/SPP1/CXCL12/OSBPL9/EGF/CEACAM1/SLC26A6/AGTR1/SLC10A7/C1QTNF1/AQP1/STARD5/OXTR/NCOA2/CAV1/PLTP/GRAMD1C/SLCO2B1/NR1H4/SYT11/ABAT/NCOA1	39
BP	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	14/2486	86/18670	0.2502	0.5118	0.4011	COG3/SCFD1/KIF26A/COPB2/TMEM115/KIF4A/KIF2C/RAB6B/KDELR3/UVRAG/ARFGAP2/BNIP1/COPZ2/KLC1	14
BP	GO:0042446	hormone biosynthetic process	14/2486	86/18670	0.2502	0.5118	0.4011	CYP11A1/TNF/BMP2/CYP21A2/HSD11B2/HSD17B14/HSD11B1/HSD17B1/DIO2/IL1B/REST/STC2/HSD17B3/DKK3	14
BP	GO:0048013	ephrin receptor signaling pathway	14/2486	86/18670	0.2502	0.5118	0.4011	SDC2/ARHGEF7/AP2A2/EPHB4/CHN1/MMP9/EFNB2/DNM1/CDK5R1/VAV3/PAK3/ARPC2/LYN/EPHB2	14
BP	GO:1903363	negative regulation of cellular protein catabolic process	14/2486	86/18670	0.2502	0.5118	0.4011	GABARAPL2/UBXN1/SMARCC1/USP7/PML/WAC/MTM1/LAPTM4B/CAMLG/UBE2G2/HSP90AB1/RPS7/TAF1/GIPC1	14
BP	GO:0046890	regulation of lipid biosynthetic process	30/2486	198/18670	0.2503	0.5118	0.4011	ORMDL1/MBTPS1/TNF/FABP5/CREB1/FBXW7/ERLIN1/SMPD3/NFYA/BMP2/APOC1/SIRT1/ERLIN2/ADIPOR2/CCDC3/CEACAM1/PRKAG2/IL1B/SORBS1/REST/WDTC1/ORMDL2/HMGCS1/MTOR/PDK4/DKK3/NR1H4/FABP3/ELOVL5/LPCAT1	30
BP	GO:0006998	nuclear envelope organization	9/2486	52/18670	0.2504	0.5118	0.4011	AKAP8L/PRKCB/TMEM170A/PPP2CA/NUP93/NUP155/PLK1/TMEM43/SUN2	9
BP	GO:0032653	regulation of interleukin-10 production	9/2486	52/18670	0.2504	0.5118	0.4011	MMP8/FCGR2B/CD83/IRF4/IL23R/PDCD1LG2/CD34/TREM2/TLR9	9
BP	GO:0032731	positive regulation of interleukin-1 beta production	9/2486	52/18670	0.2504	0.5118	0.4011	ORM1/LPL/IFI16/HSPB1/P2RX7/FZD5/NLRP1/WNT5A/NLRP7	9
BP	GO:0060421	positive regulation of heart growth	9/2486	52/18670	0.2504	0.5118	0.4011	TBX5/IGF1/MIR17HG/TBX2/NOTCH1/YAP1/ZFPM2/MTOR/PIN1	9
BP	GO:0007051	spindle organization	26/2486	170/18670	0.253	0.517	0.4052	PARP3/TACC1/DLG1/CLASP2/CEP192/TPX2/SPC25/CHMP1B/KIF4A/SENP6/HAUS8/VCP/RAE1/PLK1/MYH9/UVRAG/FLNA/HAUS2/EML1/TTK/CLASP1/RGS14/TACC2/SUN2/NEK2/LZTS2	26
BP	GO:0002688	regulation of leukocyte chemotaxis	18/2486	114/18670	0.2542	0.5194	0.4071	CSF1/VEGFC/AKIRIN1/GAS6/EDN3/THBS4/RARRES2/CXCL12/DAPK2/MTUS1/PTN/IL12A/CCL21/WNT5A/DUSP1/SLIT2/LYN/MST1	18
BP	GO:0051092	positive regulation of NF-kappaB transcription factor activity	23/2486	149/18670	0.2543	0.5194	0.4071	CLU/NFKB2/PRKCB/TNF/BCL10/LTF/DHX9/TGFB1/UBA52/CX3CL1/ZBTB7A/BTK/TRAF6/RELA/TNFRSF11A/RAB7B/IL1B/UBC/WNT5A/TLR9/ROR1/CAV1/RPS6KA5	23
BP	GO:0034763	negative regulation of transmembrane transport	20/2486	128/18670	0.2547	0.52	0.4076	GRB10/SRI/SLC9A3R1/PRKCB/TNF/TWIST1/FABP5/TGFB1/CACNB3/ADRA2A/HECW2/GPR35/MMP9/IRS2/IL1B/FKBP1B/TLR9/CAV1/MTOR/EPHB2	20
BP	GO:0042130	negative regulation of T cell proliferation	10/2486	59/18670	0.2549	0.5203	0.4078	ARG2/ARG1/DLG1/TGFB1/TWSG1/PDCD1LG2/TNFRSF14/GPNMB/SPN/RC3H1	10
BP	GO:0002251	organ or tissue specific immune response	7/2486	39/18670	0.2571	0.5235	0.4103	LTF/CAMP/RNASE3/PIGR/RPL39/OTUD7B/DEFB1	7
BP	GO:0008207	C21-steroid hormone metabolic process	7/2486	39/18670	0.2571	0.5235	0.4103	CYP11A1/DHRS9/BMP2/AKR1C2/REST/AKR1D1/DKK3	7
BP	GO:0032506	cytokinetic process	7/2486	39/18670	0.2571	0.5235	0.4103	RTKN/ARF1/ANLN/CHMP6/CHMP1B/KIF20A/MYH9	7
BP	GO:0035886	vascular smooth muscle cell differentiation	7/2486	39/18670	0.2571	0.5235	0.4103	HES1/MIR21/RAMP2/NOTCH1/SGCB/EPC1/NFATC3	7
BP	GO:0045684	positive regulation of epidermis development	7/2486	39/18670	0.2571	0.5235	0.4103	NCOA3/TNF/TGFB2/FOXC1/SFRP4/NOTCH1/WNT5A	7
BP	GO:0050856	regulation of T cell receptor signaling pathway	7/2486	39/18670	0.2571	0.5235	0.4103	BCL10/CYLD/RELA/CEACAM1/THY1/CD300A/RC3H1	7
BP	GO:2000648	positive regulation of stem cell proliferation	7/2486	39/18670	0.2571	0.5235	0.4103	VEGFC/CX3CL1/NANOG/SMO/NOTCH1/GLI3/PTPRC	7
BP	GO:0006513	protein monoubiquitination	11/2486	66/18670	0.2584	0.5249	0.4114	PEF1/BCOR/TRIM21/UBE4B/WAC/CBL/FANCL/DTX3L/UBE2D3/PCGF2/CUL1	11
BP	GO:0021872	forebrain generation of neurons	11/2486	66/18670	0.2584	0.5249	0.4114	INHBA/LHX6/PLXNA3/HES1/NRP1/SATB2/GLI3/WNT5A/SLIT2/SHANK3/LHX8	11
BP	GO:0040014	regulation of multicellular organism growth	11/2486	66/18670	0.2584	0.5249	0.4114	CSF1/NIPBL/CACNA2D2/FXN/GHRL/CREB1/IGF1/FOXS1/SMO/STC2/GHR	11
BP	GO:0006516	glycoprotein catabolic process	5/2486	26/18670	0.2595	0.5249	0.4114	EDEM1/ADAMTS9/STT3B/GPC1/ADAMTS12	5
BP	GO:0006817	phosphate ion transport	5/2486	26/18670	0.2595	0.5249	0.4114	SLC25A3/SLC20A1/SFRP4/ANKH/SLC37A4	5
BP	GO:0007020	microtubule nucleation	5/2486	26/18670	0.2595	0.5249	0.4114	CLASP2/CEP192/NIN/NDE1/CLASP1	5
BP	GO:0010460	positive regulation of heart rate	5/2486	26/18670	0.2595	0.5249	0.4114	TPM1/EDN3/GCH1/SLC1A1/RYR2	5
BP	GO:0010758	regulation of macrophage chemotaxis	5/2486	26/18670	0.2595	0.5249	0.4114	CSF1/AKIRIN1/RARRES2/MTUS1/MST1	5
BP	GO:0030318	melanocyte differentiation	5/2486	26/18670	0.2595	0.5249	0.4114	EDNRB/EDN3/ADAMTS9/SLC24A5/GLI3	5
BP	GO:0031954	positive regulation of protein autophosphorylation	5/2486	26/18670	0.2595	0.5249	0.4114	VEGFC/ACE/GPNMB/TNKS1BP1/RASSF2	5
BP	GO:0032967	positive regulation of collagen biosynthetic process	5/2486	26/18670	0.2595	0.5249	0.4114	TGFB1/PDGFRB/CREB3L1/ITGA2/LARP6	5
BP	GO:0036152	phosphatidylethanolamine acyl-chain remodeling	5/2486	26/18670	0.2595	0.5249	0.4114	PLA2G4C/PLA2G5/LPCAT4/LPCAT3/PLA2G2A	5
BP	GO:0042044	fluid transport	5/2486	26/18670	0.2595	0.5249	0.4114	ITPR1/EDNRB/SLC26A6/AQP1/HAS2	5
BP	GO:0043090	amino acid import	5/2486	26/18670	0.2595	0.5249	0.4114	SLC1A3/CLN8/SLC1A1/SLC7A3/SLC6A1	5
BP	GO:0060037	pharyngeal system development	5/2486	26/18670	0.2595	0.5249	0.4114	ACVR1/TGFB2/HES1/SIX1/TBX1	5
BP	GO:0060074	synapse maturation	5/2486	26/18670	0.2595	0.5249	0.4114	NFATC4/YWHAZ/IGSF21/PFN1/ARHGEF15	5
BP	GO:0060544	regulation of necroptotic process	5/2486	26/18670	0.2595	0.5249	0.4114	FADD/SPATA2/CYLD/MIR214/CAV1	5
BP	GO:0060706	cell differentiation involved in embryonic placenta development	5/2486	26/18670	0.2595	0.5249	0.4114	STK4/NR2F2/FZD5/E2F8/SPINT2	5
BP	GO:1903203	regulation of oxidative stress-induced neuron death	5/2486	26/18670	0.2595	0.5249	0.4114	PINK1/FBXW7/MCL1/REST/NONO	5
BP	GO:1904353	regulation of telomere capping	5/2486	26/18670	0.2595	0.5249	0.4114	USP7/PKIB/SMG6/MAPKAPK5/NEK2	5
BP	GO:1901136	carbohydrate derivative catabolic process	29/2486	192/18670	0.2604	0.5267	0.4128	IDS/CHIT1/NUDT15/EDEM1/PGLYRP1/TDG/TGFB1/LYG2/AGRN/PDE2A/SAMHD1/PDE4B/SDC2/GPC4/ADAMTS9/GPC6/BGN/STT3B/PDE1A/LYVE1/GPC1/DCN/ACAN/OGN/CSPG4/FMOD/PRELP/ADAMTS12/HYAL1	29
BP	GO:0009410	response to xenobiotic stimulus	43/2486	292/18670	0.2609	0.5271	0.4131	MAP1LC3A/FOSB/FADD/PPARG/ARG1/SNCA/CDO1/TGFB1/PDE2A/AHRR/RHBDD3/TIPARP/CYP26B1/CMBL/EGFR/AOC3/RELA/TRDMT1/FMO3/ASS1/SDK1/CBR3/GSTM5/AQP1/CPS1/NR3C1/OXTR/NR4A2/CYP2F1/RYR2/HSP90AB1/CYP3A5/MTOR/GHR/HSPA5/N6AMT1/PRKAR2B/RGS17/SLC6A1/CRYZ/NQO1/FIBIN/ABAT	43
BP	GO:0006801	superoxide metabolic process	12/2486	73/18670	0.261	0.5271	0.4131	CD177/TNF/TGFB1/PRDX2/MIR21/GCH1/EGFR/NOS3/ACP5/NOX4/SOD3/NQO1	12
BP	GO:0043627	response to estrogen	12/2486	73/18670	0.261	0.5271	0.4131	PPARG/EP300/GHRL/IGFBP2/CCND1/TRIM24/SERPINB9/PDGFRB/GLI3/TEK/SFRP1/CAV1	12
BP	GO:1901983	regulation of protein acetylation	12/2486	73/18670	0.261	0.5271	0.4131	MUC1/SNCA/TWIST1/TGFB1/FLCN/RAPGEF3/SIRT1/SETD5/IL1B/SET/RPS6KA5/SIN3A	12
BP	GO:2001257	regulation of cation channel activity	27/2486	178/18670	0.2622	0.5294	0.4149	SRI/ANXA3/SCN1B/STOM/CNIH3/DLG1/PINK1/FGF14/CACNB3/DLG2/PDE4B/GRIA3/STAC/GPR35/STAC2/MMP9/AHNAK/KCNA1/FKBP1B/TREM2/ANK2/SHISA8/CAV1/DMD/ARC/EPHB2/SHANK3	27
BP	GO:0000910	cytokinesis	26/2486	171/18670	0.263	0.5308	0.416	CIT/RTKN/ARF1/APC/RAB11FIP4/UNC119/ANLN/FLCN/CHMP6/CHMP1B/KIF4A/BCL2L1/PKP4/PLK3/PLK1/KIF20A/MYH9/UVRAG/PKN2/MYH10/E2F8/GIPC1/SETD2/KIF14/LZTS2/PIN1	26
BP	GO:0014075	response to amine	8/2486	46/18670	0.2639	0.5323	0.4172	ARG1/TRDMT1/ASS1/CPS1/OXTR/NR4A2/ITGA2/RGS17	8
BP	GO:0019731	antibacterial humoral response	8/2486	46/18670	0.2639	0.5323	0.4172	SLPI/CTSG/LTF/ELANE/CAMP/RNASE3/RPL39/DEFB1	8
BP	GO:0051054	positive regulation of DNA metabolic process	34/2486	228/18670	0.2642	0.5327	0.4175	ANXA3/OTUD4/PARP3/JUN/DHX9/TGFB1/FUS/HSP90AA1/PARP9/FBXO4/USP7/DDX11/SIRT1/EXOSC3/EGFR/PML/SMOC2/PKIB/DBF4/IL2/CCT8/KLF4/PDGFRB/DTX3L/NOX4/PAK3/HSP90AB1/MAPKAPK5/TNFAIP1/E2F8/MGMT/PTPRC/NEK2/RNF8	34
BP	GO:0006112	energy reserve metabolic process	14/2486	87/18670	0.2643	0.5327	0.4175	GNMT/UGP2/IGF1/IRS2/KHK/PRKAG2/SORBS1/PYGB/GFPT2/MTOR/PPP1R3C/KL/PHKA1/MRAP2	14
BP	GO:0051781	positive regulation of cell division	14/2486	87/18670	0.2643	0.5327	0.4175	SIRT2/CIT/TGFB2/VEGFC/TGFB1/TAL1/THBS4/PTN/PKP4/YBX1/IL1B/PKN2/GIPC1/KIF14	14
BP	GO:1905952	regulation of lipid localization	24/2486	157/18670	0.2644	0.5327	0.4175	ITGB3/PPARG/NFKBIA/TNF/LPL/GHRL/CYP4F2/FBXW7/ZC3H12A/MSR1/APOC1/SIRT1/SPP1/P2RX7/EGF/TNFRSF11A/HNRNPK/IRS2/AGTR1/C1QTNF1/IL1B/TRIAP1/PLTP/FABP3	24
BP	GO:0031056	regulation of histone modification	22/2486	143/18670	0.2656	0.5349	0.4192	MUC1/BCOR/AKAP8L/NIPBL/SNCA/TWIST1/TGFB1/PINK1/CDK9/FLCN/SIRT1/SETD5/NSD1/JARID2/IL1B/WDR70/AKAP8/CTCFL/SET/RPS6KA5/SIN3A/MTHFR	22
BP	GO:0034440	lipid oxidation	16/2486	101/18670	0.266	0.5355	0.4197	ACAD10/PPARG/CPT1C/TWIST1/CYGB/ETFDH/SESN2/ACAT2/ADIPOR2/IRS2/PRKAG2/ETFA/CRAT/MTOR/PDK4/FABP3	16
BP	GO:0015696	ammonium transport	17/2486	108/18670	0.2664	0.5358	0.4199	ITGB3/SLC18A1/SLC6A8/RHD/SNCA/PINK1/RHCE/BTK/CXCL12/AQP1/SNAP23/LYN/SLC44A2/ADCYAP1/SLC25A29/SYT11/ABAT	17
BP	GO:2000278	regulation of DNA biosynthetic process	17/2486	108/18670	0.2664	0.5358	0.4199	PPARG/PARP3/HSP90AA1/DCP2/FBXO4/SMOC2/PKIB/CCT8/KLF4/PDGFRB/NOX4/SMG6/PAK3/DUSP1/HSP90AB1/MAPKAPK5/NEK2	17
BP	GO:0043500	muscle adaptation	19/2486	122/18670	0.2665	0.5358	0.4199	CAMK2G/YY1/NOL3/CDK9/LMCD1/MIR21/GTF2IRD1/NOS3/IGF1/MIR17HG/IGFBP5/KLF4/NOTCH1/JARID2/IL1B/MIR214/INPP5F/MTOR/PIN1	19
BP	GO:0010927	cellular component assembly involved in morphogenesis	18/2486	115/18670	0.2666	0.5358	0.4199	TMOD1/MPP5/CD9/TPM1/AKAP13/CLASP2/OBSL1/LDB3/PDGFRA/PHLDB2/LMOD1/PDGFRB/GPC1/ANK2/CSRP2/CLASP1/MYH10/CSRP1	18
BP	GO:0030449	regulation of complement activation	18/2486	115/18670	0.2666	0.5358	0.4199	CLU/PROS1/C1QB/C1QA/C1QC/CR1L/CFH/CD59/C2/CFB/SERPING1/CFHR2/CPN1/C1R/IL1B/C1S/CFI/A2M	18
BP	GO:0006164	purine nucleotide biosynthetic process	44/2486	300/18670	0.2671	0.5368	0.4207	ADCY3/PDPR/GUCY2D/SLC4A1/SNCA/ADCY7/NUP93/TGFB1/PINK1/ADCY4/PFKFB2/LDHC/DHTKD1/FLCN/ZBTB7A/NUP50/NME5/NOS3/ADCY6/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/ELOVL7/VCP/RAE1/NUP188/NUP160/NUP54/PDP1/NUP214/NUP155/FOXK2/AMPD2/NUPR1/SLC2A6/PRKAG2/TREM2/PFAS/PANK1/PDK4/ELOVL5/PFKP	44
BP	GO:0006644	phospholipid metabolic process	62/2486	430/18670	0.2677	0.5377	0.4214	SOCS7/TTC7B/PLA2G4C/BMX/INPP5D/ARF1/PTPN13/PIGH/SNCA/FLT1/FABP5/PLEKHA4/LPL/PLEKHA3/TGFB1/PLEKHA2/PTDSS1/PLA2G5/SMPD3/P2RY12/CLN8/PIGX/APOC1/LPCAT4/PIGA/PLCB2/GNB3/IDI2/PLCB1/MTMR14/SERINC3/PDGFRA/GDPD1/PIK3CD/DOLK/KLF4/PDGFRB/MTM1/LPCAT3/MFSD2A/PLA2G2A/TEK/PLCD4/CCL21/MTMR12/ENPP2/WDR91/VAV3/PIGY/HMGCS1/DGKZ/SLC44A3/INPP5F/LYN/SLC44A2/PIGL/MTMR7/PCYT1A/MTMR4/NR1H4/FABP3/LPCAT1	62
BP	GO:0009260	ribonucleotide biosynthetic process	43/2486	293/18670	0.2686	0.5393	0.4227	ADCY3/PDPR/GUCY2D/SLC4A1/SNCA/ADCY7/NUP93/TGFB1/PINK1/ADCY4/PFKFB2/LDHC/DHTKD1/FLCN/ZBTB7A/NUP50/NME5/ADCY6/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/ELOVL7/VCP/RAE1/NUP188/NUP160/NUP54/PDP1/NUP214/NUP155/FOXK2/AMPD2/NUPR1/SLC2A6/PRKAG2/TREM2/PFAS/PANK1/PDK4/ELOVL5/PFKP	43
BP	GO:0010043	response to zinc ion	9/2486	53/18670	0.2688	0.5396	0.4229	ARG1/CREB1/MT2A/P2RX7/ASS1/KHK/HVCN1/KCNK3/CPS1	9
BP	GO:0010039	response to iron ion	6/2486	33/18670	0.2711	0.5408	0.4239	C1QA/MAP1LC3A/SNCA/FXN/CCND1/ABAT	6
BP	GO:0016242	negative regulation of macroautophagy	6/2486	33/18670	0.2711	0.5408	0.4239	SCFD1/PINK1/SMCR8/MTM1/NUPR1/MTOR	6
BP	GO:0016486	peptide hormone processing	6/2486	33/18670	0.2711	0.5408	0.4239	MME/CTSG/ACE/PCSK6/CPE/ENPEP	6
BP	GO:0019934	cGMP-mediated signaling	6/2486	33/18670	0.2711	0.5408	0.4239	EDNRB/PRKAR2A/PDE2A/RUNDC3A/AQP1/PRKAR2B	6
BP	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	6/2486	33/18670	0.2711	0.5408	0.4239	SRI/GHRL/C2CD2L/STX4/PPP3CB/NR1H4	6
BP	GO:0036314	response to sterol	6/2486	33/18670	0.2711	0.5408	0.4239	GRAMD1B/INHBA/TGFB1/SMO/HMGCS1/GRAMD1C	6
BP	GO:1901797	negative regulation of signal transduction by p53 class mediator	6/2486	33/18670	0.2711	0.5408	0.4239	MUC1/TWIST1/MIR21/BDKRB2/SIRT1/TRIAP1	6
BP	GO:0002320	lymphoid progenitor cell differentiation	4/2486	20/18670	0.2718	0.5408	0.4239	HES1/FLCN/BATF/NOTCH1	4
BP	GO:0002374	cytokine secretion involved in immune response	4/2486	20/18670	0.2718	0.5408	0.4239	TRIM6/TNF/TNFRSF14/WNT5A	4
BP	GO:0002827	positive regulation of T-helper 1 type immune response	4/2486	20/18670	0.2718	0.5408	0.4239	IL1R1/HLX/IL23R/IL1B	4
BP	GO:0003215	cardiac right ventricle morphogenesis	4/2486	20/18670	0.2718	0.5408	0.4239	TGFB2/MIR17HG/NOTCH1/ZFPM2	4
BP	GO:0007549	dosage compensation	4/2486	20/18670	0.2718	0.5408	0.4239	XIST/YTHDC1/EIF1/RLIM	4
BP	GO:0007620	copulation	4/2486	20/18670	0.2718	0.5408	0.4239	EDNRB/ACVR2A/OXTR/ABAT	4
BP	GO:0010042	response to manganese ion	4/2486	20/18670	0.2718	0.5408	0.4239	ARG1/EIF2S1/HSPA5/FIBIN	4
BP	GO:0030903	notochord development	4/2486	20/18670	0.2718	0.5408	0.4239	SOX9/YAP1/WNT5A/COL5A2	4
BP	GO:0032816	positive regulation of natural killer cell activation	4/2486	20/18670	0.2718	0.5408	0.4239	GAS6/IL23R/IL12A/AXL	4
BP	GO:0034143	regulation of toll-like receptor 4 signaling pathway	4/2486	20/18670	0.2718	0.5408	0.4239	TNFAIP3/LTF/RAB7B/LYN	4
BP	GO:0035458	cellular response to interferon-beta	4/2486	20/18670	0.2718	0.5408	0.4239	TRIM6/IRF1/IFI16/UBE2G2	4
BP	GO:0045019	negative regulation of nitric oxide biosynthetic process	4/2486	20/18670	0.2718	0.5408	0.4239	ZC3H12A/CD34/ACP5/CAV1	4
BP	GO:0045655	regulation of monocyte differentiation	4/2486	20/18670	0.2718	0.5408	0.4239	INPP5D/CSF1/JUN/HOXA7	4
BP	GO:0048148	behavioral response to cocaine	4/2486	20/18670	0.2718	0.5408	0.4239	FADD/SNCA/SDK1/ABAT	4
BP	GO:0048745	smooth muscle tissue development	4/2486	20/18670	0.2718	0.5408	0.4239	DLG1/TIPARP/SIX1/SOX9	4
BP	GO:0051797	regulation of hair follicle development	4/2486	20/18670	0.2718	0.5408	0.4239	TNF/TGFB2/SMO/WNT5A	4
BP	GO:0072234	metanephric nephron tubule development	4/2486	20/18670	0.2718	0.5408	0.4239	HES1/WWTR1/SOX9/YAP1	4
BP	GO:0097062	dendritic spine maintenance	4/2486	20/18670	0.2718	0.5408	0.4239	CTTN/FCGR2B/IGF1R/ITGA3	4
BP	GO:1902993	positive regulation of amyloid precursor protein catabolic process	4/2486	20/18670	0.2718	0.5408	0.4239	CLU/TNF/LYN/SPON1	4
BP	GO:1903978	regulation of microglial cell activation	4/2486	20/18670	0.2718	0.5408	0.4239	MMP8/CX3CL1/TREM2/PTPRC	4
BP	GO:1904406	negative regulation of nitric oxide metabolic process	4/2486	20/18670	0.2718	0.5408	0.4239	ZC3H12A/CD34/ACP5/CAV1	4
BP	GO:0046324	regulation of glucose import	10/2486	60/18670	0.2723	0.5416	0.4245	GRB10/RTN2/TNF/IGF1/ADIPOR2/SLC25A27/IRS2/PRKAG2/SORBS1/CAPN10	10
BP	GO:0060038	cardiac muscle cell proliferation	11/2486	67/18670	0.2749	0.5465	0.4283	MAPK11/TBX5/TGFB2/SMAD1/FOXC1/MIR17HG/TBX2/NOTCH1/YAP1/JARID2/ZFPM2	11
BP	GO:0060271	cilium assembly	53/2486	366/18670	0.2752	0.5471	0.4288	ABLIM3/GAS8/C5orf30/B9D1/DZIP1L/HSP90AA1/CEP192/WDR11/B9D2/RSPH9/WDR19/WWTR1/NME5/CYLD/FNBP1L/AVIL/CEP135/HAUS8/BBS1/ODF2/SCLT1/NPHP1/TTBK2/PLK1/IFT140/CDKL1/NOTCH1/DYNLRB1/ARMC9/C2CD3/LRRC49/ADAMTS16/FLNA/HAUS2/DZIP1/NDE1/DNALI1/SSNA1/CLASP1/TMEM17/IFT81/DNAH5/INTU/TMEM231/DYNLL2/TMEM67/RAB8A/CCDC113/PRKAR2B/ATXN10/FHDC1/PARVA/NEK2	53
BP	GO:0030104	water homeostasis	12/2486	74/18670	0.2767	0.5493	0.4305	ADCY3/PRKAR2A/ADCY7/SCT/CYP4F2/ADCY4/CYP26B1/ADCY6/AQP1/HAS2/WFS1/PRKAR2B	12
BP	GO:0032418	lysosome localization	12/2486	74/18670	0.2767	0.5493	0.4305	SYTL4/PDPK1/STXBP1/BTK/C12orf4/CBL/PIK3CD/IL13RA2/SNAP23/MYH9/CD300A/LYN	12
BP	GO:0043507	positive regulation of JUN kinase activity	12/2486	74/18670	0.2767	0.5493	0.4305	TNF/ERN1/TRAF6/MAP3K2/SAMD5/MAP3K5/TNFRSF11A/FZD10/FZD5/WNT5A/TLR9/FZD4	12
BP	GO:1900076	regulation of cellular response to insulin stimulus	12/2486	74/18670	0.2767	0.5493	0.4305	GRB10/PRKCB/LPL/SORL1/GRB14/SIRT1/RELA/SESN3/MYO1C/IL1B/SORBS1/NR1H4	12
BP	GO:0009124	nucleoside monophosphate biosynthetic process	31/2486	208/18670	0.277	0.5497	0.4308	SLC4A1/NUP93/TGFB1/PINK1/PFKFB2/LDHC/DHTKD1/FLCN/ZBTB7A/NUP50/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/VCP/RAE1/NUP188/NUP160/NUP54/NUP214/NUP155/FOXK2/AMPD2/NUPR1/SLC2A6/PRKAG2/TK1/TREM2/PFAS/PFKP	31
BP	GO:1903670	regulation of sprouting angiogenesis	21/2486	137/18670	0.2775	0.5505	0.4315	PDPK1/GHRL/NRP1/FBXW7/SMAD1/MMRN2/JAK1/ADAMTS9/CARD10/RHOJ/CEACAM1/SRPX2/AGTR1/MEOX2/KLF4/APLNR/CREB3L1/NOTCH1/PDCD10/MAP3K3/KDR	21
BP	GO:0048708	astrocyte differentiation	13/2486	81/18670	0.278	0.5512	0.432	C1QA/TNF/TAL1/HES1/BMP2/EGFR/SMO/SOX9/NOTCH1/IL1B/TREM2/ROR1/SOX6	13
BP	GO:0006997	nucleus organization	20/2486	130/18670	0.2782	0.5513	0.4321	AKAP8L/PRKCB/TMEM170A/PPP2CA/NUP93/USPL1/SRPK2/NOLC1/CHMP6/CHMP1B/EMG1/PML/NUP153/NUP54/NUP155/PLK1/CHD5/TMEM43/SUN2/RNF8	20
BP	GO:0032088	negative regulation of NF-kappaB transcription factor activity	14/2486	88/18670	0.2788	0.5513	0.4321	TNFAIP3/NFKBIA/PRDX2/TRIM21/ITCH/ZC3H12A/G3BP2/USP7/SIRT1/CYLD/KLF4/TLR9/NR1H4/ADORA3	14
BP	GO:0042147	retrograde transport, endosome to Golgi	14/2486	88/18670	0.2788	0.5513	0.4321	TRAPPC10/VPS53/TBC1D10A/TMEM87A/STX16/PLEKHJ1/DENND2A/RAB7B/GOSR1/RAB6B/TBC1D23/VPS26B/HEATR5B/MAGEL2	14
BP	GO:0070125	mitochondrial translational elongation	14/2486	88/18670	0.2788	0.5513	0.4321	TSFM/MRPL36/MRPL44/MRPL48/MRPL15/MRPL20/MRPS28/MRPS14/MRPL18/MRPL13/MRPL21/MRPL17/MRPL54/MRPL2	14
BP	GO:0021532	neural tube patterning	7/2486	40/18670	0.2788	0.5513	0.4321	HES1/WDR19/SMO/IFT140/GLI3/FKBP8/SSBP3	7
BP	GO:0032008	positive regulation of TOR signaling	7/2486	40/18670	0.2788	0.5513	0.4321	RRAGA/GAS6/FLCN/TELO2/SMCR8/SIK3/TREM2	7
BP	GO:0042036	negative regulation of cytokine biosynthetic process	7/2486	40/18670	0.2788	0.5513	0.4321	INPP5D/INHBA/GHRL/ELANE/ZFP36/KLF4/PTPRC	7
BP	GO:0046621	negative regulation of organ growth	7/2486	40/18670	0.2788	0.5513	0.4321	YY1/MAPK11/TBX5/FXN/MIR17HG/STK4/JARID2	7
BP	GO:2000008	regulation of protein localization to cell surface	7/2486	40/18670	0.2788	0.5513	0.4321	BDNF/TNF/RAB11FIP5/EGF/LRIG2/STX4/HSP90AB1	7
BP	GO:2000257	regulation of protein activation cascade	18/2486	116/18670	0.2791	0.5516	0.4323	CLU/PROS1/C1QB/C1QA/C1QC/CR1L/CFH/CD59/C2/CFB/SERPING1/CFHR2/CPN1/C1R/IL1B/C1S/CFI/A2M	18
BP	GO:0042102	positive regulation of T cell proliferation	15/2486	95/18670	0.2792	0.5516	0.4323	HLA-DPB1/FADD/IGFBP2/CD276/HES1/MIR21/TRAF6/IL23R/IGF1/PDCD1LG2/IL12A/IL2/IL1B/PTPRC/CORO1A	15
BP	GO:0042116	macrophage activation	15/2486	95/18670	0.2792	0.5516	0.4323	CLU/C1QA/SUCNR1/MMP8/SNCA/TNF/JUN/FCGR2B/CX3CL1/ZC3H12A/JMJD6/IL33/TREM2/WNT5A/PTPRC	15
BP	GO:0051149	positive regulation of muscle cell differentiation	17/2486	109/18670	0.2793	0.5517	0.4324	RBM4/MAPK11/TGFB1/CYP26B1/BOC/MIR21/EHD2/SIRT1/IGF1/EFNB2/CDON/MORF4L2/SHOX2/TBX1/MTOR/PIN1/OLFM2	17
BP	GO:0070613	regulation of protein processing	27/2486	180/18670	0.2822	0.5526	0.4331	CLU/PROS1/C1QB/C1QA/C1QC/CR1L/CFH/NOL3/CD59/GAS1/C2/CFB/SERPING1/CFHR2/CPN1/TMEM98/C1R/MYH9/IL1B/RNF139/C1S/CFI/A2M/SPON1/CLEC3B/CCBE1/NLRP7	27
BP	GO:0002091	negative regulation of receptor internalization	3/2486	14/18670	0.2834	0.5526	0.4331	ANKRD13D/ANKRD13B/ANKRD13A	3
BP	GO:0002523	leukocyte migration involved in inflammatory response	3/2486	14/18670	0.2834	0.5526	0.4331	ELANE/CX3CL1/PTN	3
BP	GO:0002834	regulation of response to tumor cell	3/2486	14/18670	0.2834	0.5526	0.4331	FBXO38/CEACAM1/IL12A	3
BP	GO:0002837	regulation of immune response to tumor cell	3/2486	14/18670	0.2834	0.5526	0.4331	FBXO38/CEACAM1/IL12A	3
BP	GO:0007501	mesodermal cell fate specification	3/2486	14/18670	0.2834	0.5526	0.4331	SFRP2/HOXA11/SIX2	3
BP	GO:0009214	cyclic nucleotide catabolic process	3/2486	14/18670	0.2834	0.5526	0.4331	PDE2A/PDE4B/PDE1A	3
BP	GO:0010421	hydrogen peroxide-mediated programmed cell death	3/2486	14/18670	0.2834	0.5526	0.4331	PINK1/MIR21/PDCD10	3
BP	GO:0010935	regulation of macrophage cytokine production	3/2486	14/18670	0.2834	0.5526	0.4331	TGFB2/TGFB1/WNT5A	3
BP	GO:0014841	skeletal muscle satellite cell proliferation	3/2486	14/18670	0.2834	0.5526	0.4331	AKIRIN1/SIX1/SIX5	3
BP	GO:0014857	regulation of skeletal muscle cell proliferation	3/2486	14/18670	0.2834	0.5526	0.4331	AKIRIN1/SIX1/SIX5	3
BP	GO:0021535	cell migration in hindbrain	3/2486	14/18670	0.2834	0.5526	0.4331	TTBK2/POU4F1/FLNA	3
BP	GO:0021781	glial cell fate commitment	3/2486	14/18670	0.2834	0.5526	0.4331	TAL1/SOX9/SOX6	3
BP	GO:0031272	regulation of pseudopodium assembly	3/2486	14/18670	0.2834	0.5526	0.4331	APC/CCL21/CDC42EP5	3
BP	GO:0032310	prostaglandin secretion	3/2486	14/18670	0.2834	0.5526	0.4331	P2RX7/TNFRSF11A/IL1B	3
BP	GO:0034331	cell junction maintenance	3/2486	14/18670	0.2834	0.5526	0.4331	CD177/PLEKHA7/PARD6A	3
BP	GO:0035358	regulation of peroxisome proliferator activated receptor signaling pathway	3/2486	14/18670	0.2834	0.5526	0.4331	TWIST1/FABP5/SIRT1	3
BP	GO:0035791	platelet-derived growth factor receptor-beta signaling pathway	3/2486	14/18670	0.2834	0.5526	0.4331	LOX/PDGFRB/PDGFRL	3
BP	GO:0042487	regulation of odontogenesis of dentin-containing tooth	3/2486	14/18670	0.2834	0.5526	0.4331	CSF1/BMP2/DMRT3	3
BP	GO:0042574	retinal metabolic process	3/2486	14/18670	0.2834	0.5526	0.4331	CYP27C1/ALDH1A3/ALDH1A2	3
BP	GO:0045198	establishment of epithelial cell apical/basal polarity	3/2486	14/18670	0.2834	0.5526	0.4331	SLC9A3R1/MSN/WNT5A	3
BP	GO:0045591	positive regulation of regulatory T cell differentiation	3/2486	14/18670	0.2834	0.5526	0.4331	DUSP10/TGFB1/IL2	3
BP	GO:0045605	negative regulation of epidermal cell differentiation	3/2486	14/18670	0.2834	0.5526	0.4331	HOXA7/HES1/NOTCH1	3
BP	GO:0048308	organelle inheritance	3/2486	14/18670	0.2834	0.5526	0.4331	YWHAZ/PLK3/PDCD10	3
BP	GO:0048313	Golgi inheritance	3/2486	14/18670	0.2834	0.5526	0.4331	YWHAZ/PLK3/PDCD10	3
BP	GO:0050667	homocysteine metabolic process	3/2486	14/18670	0.2834	0.5526	0.4331	CPS1/NOX4/MTHFR	3
BP	GO:0050930	induction of positive chemotaxis	3/2486	14/18670	0.2834	0.5526	0.4331	NTF3/VEGFC/CXCL12	3
BP	GO:0051547	regulation of keratinocyte migration	3/2486	14/18670	0.2834	0.5526	0.4331	MMP9/HAS2/MTOR	3
BP	GO:0051938	L-glutamate import	3/2486	14/18670	0.2834	0.5526	0.4331	SLC1A3/CLN8/SLC1A1	3
BP	GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development	3/2486	14/18670	0.2834	0.5526	0.4331	IGF1/MTOR/PIN1	3
BP	GO:0070669	response to interleukin-2	3/2486	14/18670	0.2834	0.5526	0.4331	JAK1/IL2/CDC5L	3
BP	GO:0071391	cellular response to estrogen stimulus	3/2486	14/18670	0.2834	0.5526	0.4331	TRIM24/SERPINB9/SFRP1	3
BP	GO:0080009	mRNA methylation	3/2486	14/18670	0.2834	0.5526	0.4331	WTAP/ZC3H13/PCIF1	3
BP	GO:0086069	bundle of His cell to Purkinje myocyte communication	3/2486	14/18670	0.2834	0.5526	0.4331	GJA5/JUP/KCNA5	3
BP	GO:0090128	regulation of synapse maturation	3/2486	14/18670	0.2834	0.5526	0.4331	NFATC4/YWHAZ/ARHGEF15	3
BP	GO:0090151	establishment of protein localization to mitochondrial membrane	3/2486	14/18670	0.2834	0.5526	0.4331	TIMM10/HSP90AA1/PDCD5	3
BP	GO:0097468	programmed cell death in response to reactive oxygen species	3/2486	14/18670	0.2834	0.5526	0.4331	PINK1/MIR21/PDCD10	3
BP	GO:1903054	negative regulation of extracellular matrix organization	3/2486	14/18670	0.2834	0.5526	0.4331	TGFB1/NOTCH1/FAP	3
BP	GO:1904748	regulation of apoptotic process involved in development	3/2486	14/18670	0.2834	0.5526	0.4331	TGFB2/FOXC1/NOTCH1	3
BP	GO:2001279	regulation of unsaturated fatty acid biosynthetic process	3/2486	14/18670	0.2834	0.5526	0.4331	FABP5/SIRT1/IL1B	3
BP	GO:0035722	interleukin-12-mediated signaling pathway	8/2486	47/18670	0.284	0.5528	0.4333	ARF1/CA1/JAK1/MSN/PLCB1/IL12A/CAPZA1/HSPA9	8
BP	GO:0051181	cofactor transport	8/2486	47/18670	0.284	0.5528	0.4333	SLC9A3R1/LCN2/LMBRD1/ABCB6/P2RX7/ABCB7/SLC23A1/SLC25A29	8
BP	GO:0060986	endocrine hormone secretion	8/2486	47/18670	0.284	0.5528	0.4333	INHBA/GHRL/RAB11FIP1/RAB11FIP5/AGTR1/C1QTNF1/IL1B/FZD4	8
BP	GO:0061383	trabecula morphogenesis	8/2486	47/18670	0.284	0.5528	0.4333	TGFB2/FBN2/SEMA4D/UBE4B/THBS3/NOTCH1/TEK/SFRP1	8
BP	GO:0070231	T cell apoptotic process	8/2486	47/18670	0.284	0.5528	0.4333	ARG2/FADD/BCL10/GLI3/WNT5A/BAK1/TSC22D3/DOCK8	8
BP	GO:0070849	response to epidermal growth factor	8/2486	47/18670	0.284	0.5528	0.4333	PDPK1/BAG4/ZFP36/FOXC1/EGFR/EEF1A1/CBL/SOX9	8
BP	GO:0000188	inactivation of MAPK activity	5/2486	27/18670	0.2865	0.5554	0.4353	DUSP10/PPP2CA/DUSP1/CAV1/DUSP18	5
BP	GO:0002825	regulation of T-helper 1 type immune response	5/2486	27/18670	0.2865	0.5554	0.4353	IL1R1/HLX/IL23R/IL1B/IL33	5
BP	GO:0006706	steroid catabolic process	5/2486	27/18670	0.2865	0.5554	0.4353	HSD3B7/SPP1/HSD17B14/AKR1D1/CYP39A1	5
BP	GO:0006730	one-carbon metabolic process	5/2486	27/18670	0.2865	0.5554	0.4353	GNMT/CA1/ALDH1L2/MAT2A/MTHFR	5
BP	GO:0007176	regulation of epidermal growth factor-activated receptor activity	5/2486	27/18670	0.2865	0.5554	0.4353	FBXW7/ADRA2A/CHMP6/EGF/CBL	5
BP	GO:0010714	positive regulation of collagen metabolic process	5/2486	27/18670	0.2865	0.5554	0.4353	TGFB1/PDGFRB/CREB3L1/ITGA2/LARP6	5
BP	GO:0036475	neuron death in response to oxidative stress	5/2486	27/18670	0.2865	0.5554	0.4353	PINK1/FBXW7/MCL1/REST/NONO	5
BP	GO:0039528	cytoplasmic pattern recognition receptor signaling pathway in response to virus	5/2486	27/18670	0.2865	0.5554	0.4353	GPATCH3/IFIH1/TSPAN6/RNF125/ZCCHC3	5
BP	GO:0045671	negative regulation of osteoclast differentiation	5/2486	27/18670	0.2865	0.5554	0.4353	INPP5D/LTF/FBXW7/SFRP1/FBN1	5
BP	GO:0051953	negative regulation of amine transport	5/2486	27/18670	0.2865	0.5554	0.4353	SNCA/TRH/ADRA2A/P2RY12/ABAT	5
BP	GO:0098810	neurotransmitter reuptake	5/2486	27/18670	0.2865	0.5554	0.4353	ITGB3/SLC18A1/SNCA/CLN8/SLC6A1	5
BP	GO:1905208	negative regulation of cardiocyte differentiation	5/2486	27/18670	0.2865	0.5554	0.4353	YY1/BMP2/EGFR/FRS2/SOX6	5
BP	GO:2000144	positive regulation of DNA-templated transcription, initiation	5/2486	27/18670	0.2865	0.5554	0.4353	BCLAF1/TWIST1/JUN/CREB1/TAF1	5
BP	GO:0032655	regulation of interleukin-12 production	9/2486	54/18670	0.2876	0.5574	0.4369	IRF8/MAPK11/IRF1/TRAF6/IL23R/RELA/PLCB1/ACP5/TLR9	9
BP	GO:0007605	sensory perception of sound	22/2486	145/18670	0.2881	0.5582	0.4375	SPRY2/COCH/SLC9A3R1/MBP/NAV2/NIPBL/TUB/SLC1A3/TIMM10/DIAPH1/THRB/LOXHD1/SOBP/SIX1/GJB6/LRIG2/ROR1/TBX1/FZD4/WFS1/ALDH7A1/MYO15A	22
BP	GO:0007040	lysosome organization	10/2486	61/18670	0.2901	0.5614	0.44	MBTPS1/ARF1/LYST/GNPTAB/CLN8/P2RX7/RAB7B/TMEM199/LAPTM4B/CORO1A	10
BP	GO:0048645	animal organ formation	10/2486	61/18670	0.2901	0.5614	0.44	TBX5/SPRY1/HES1/SIX1/SULF1/FRS2/GLI3/HOXA11/WNT5A/HOXA3	10
BP	GO:0080171	lytic vacuole organization	10/2486	61/18670	0.2901	0.5614	0.44	MBTPS1/ARF1/LYST/GNPTAB/CLN8/P2RX7/RAB7B/TMEM199/LAPTM4B/CORO1A	10
BP	GO:0009100	glycoprotein metabolic process	60/2486	419/18670	0.2907	0.5626	0.4409	MUC1/COG3/IDS/B3GALT4/EDEM1/GATA1/TRAK1/AGA/SDF2L1/B4GALT2/GALNT3/GNPTAB/SERP1/PCSK6/TNIP1/FKRP/TMTC4/BMP2/TMEM115/IGF1/ADAMTS9/VCP/CHST3/PLCB1/MFNG/BGN/DOLK/DDOST/HS3ST2/MAN2A2/SULF1/MGAT2/B3GALNT1/GALNT14/STT3B/CCL21/MUC2/GPC1/FOXL1/DCN/UBE2G2/RNF139/GALNT5/ALG14/ACAN/RNF103/GALNT6/CSPG4/GFPT2/PRKCSH/MAN2A1/ENGASE/MUC3A/ST6GAL1/TUSC3/SDF2/ADAMTS12/B4GALT4/HYAL1/C1GALT1C1	60
BP	GO:0046323	glucose import	11/2486	68/18670	0.2917	0.5639	0.442	GRB10/RTN2/TNF/SESN2/IGF1/ADIPOR2/SLC25A27/IRS2/PRKAG2/SORBS1/CAPN10	11
BP	GO:0050891	multicellular organismal water homeostasis	11/2486	68/18670	0.2917	0.5639	0.442	ADCY3/PRKAR2A/ADCY7/CYP4F2/ADCY4/CYP26B1/ADCY6/AQP1/HAS2/WFS1/PRKAR2B	11
BP	GO:0050918	positive chemotaxis	11/2486	68/18670	0.2917	0.5639	0.442	NTF3/VEGFC/NRP1/CX3CL1/CXCL12/ANGPT2/GPNMB/WNT5A/KDR/ITGA2/CORO1A	11
BP	GO:0043666	regulation of phosphoprotein phosphatase activity	18/2486	117/18670	0.2918	0.564	0.442	PPP1R15A/PPP1R15B/HSP90B1/TNF/PHACTR4/RCAN2/PPP2R5E/PTN/PDGFRB/FKBP1B/MAGI2/CD300A/HSP90AB1/MTOR/SET/STYXL1/PTPRC/IGFBP3	18
BP	GO:0002200	somatic diversification of immune receptors	12/2486	75/18670	0.2927	0.5655	0.4432	MSH6/POLB/PARP3/TGFB1/SAMHD1/EXO1/EXOSC3/BATF/IL2/MCM3AP/PTPRC/RNF8	12
BP	GO:0010833	telomere maintenance via telomere lengthening	13/2486	82/18670	0.2933	0.5662	0.4438	RFC1/HSP90AA1/DCP2/TELO2/FBXO4/PKIB/CCT8/SMG6/HSP90AB1/MAPKAPK5/TNKS1BP1/NHP2/NEK2	13
BP	GO:0010660	regulation of muscle cell apoptotic process	15/2486	96/18670	0.2933	0.5662	0.4438	PDPK1/PPARG/NOL3/MIR21/ZC3H12A/SIRT1/SFRP2/MAP3K5/IGF1/STK4/IL12A/NUPR1/PDE1A/HSPB6/ADCYAP1	15
BP	GO:0070126	mitochondrial translational termination	14/2486	89/18670	0.2934	0.5662	0.4438	MRPL36/MRPL44/MRPL48/MRPL15/MRPL20/MRPS28/MRPS14/MRPL18/MRPL13/MRPL21/MRPL17/MRPL54/MRPL2/GFM2	14
BP	GO:1901019	regulation of calcium ion transmembrane transporter activity	14/2486	89/18670	0.2934	0.5662	0.4438	SRI/FGF14/CACNB3/ADRA2A/PDE4B/STAC/GPR35/STAC2/AHNAK/FKBP1B/ANK2/TLR9/RYR2/DMD	14
BP	GO:0046474	glycerophospholipid biosynthetic process	32/2486	217/18670	0.2943	0.5673	0.4447	BMX/INPP5D/ARF1/PTPN13/PIGH/FABP5/PLEKHA4/PLEKHA3/PLEKHA2/PTDSS1/PLA2G5/PIGX/LPCAT4/PIGA/MTMR14/PIK3CD/MTM1/MFSD2A/PLA2G2A/MTMR12/PIGY/DGKZ/SLC44A3/INPP5F/SLC44A2/PIGL/MTMR7/PCYT1A/MTMR4/NR1H4/FABP3/LPCAT1	32
BP	GO:0071804	cellular potassium ion transport	32/2486	217/18670	0.2943	0.5673	0.4447	KCNK17/SLC24A3/KCNC4/DLG1/KCNJ15/ATP1B2/SLC1A3/KCNN3/KCNA6/MIR21/P2RY12/EDN3/KCND3/SLC12A8/KCNK10/SLC24A5/KCNA5/KCNMA1/AQP1/KCNK3/KCNJ8/KCNK6/KCNA1/TREM2/ANK2/TRPM5/FLNA/KCNT2/CAV1/KCNS3/KCNK1/KCNA3	32
BP	GO:0071805	potassium ion transmembrane transport	32/2486	217/18670	0.2943	0.5673	0.4447	KCNK17/SLC24A3/KCNC4/DLG1/KCNJ15/ATP1B2/SLC1A3/KCNN3/KCNA6/MIR21/P2RY12/EDN3/KCND3/SLC12A8/KCNK10/SLC24A5/KCNA5/KCNMA1/AQP1/KCNK3/KCNJ8/KCNK6/KCNA1/TREM2/ANK2/TRPM5/FLNA/KCNT2/CAV1/KCNS3/KCNK1/KCNA3	32
BP	GO:0034205	amyloid-beta formation	6/2486	34/18670	0.2953	0.5686	0.4457	CLU/TNF/SORL1/IGF1/SPON1/PIN1	6
BP	GO:0060795	cell fate commitment involved in formation of primary germ layer	6/2486	34/18670	0.2953	0.5686	0.4457	NANOG/SMAD1/SFRP2/KLF4/HOXA11/SIX2	6
BP	GO:0071868	cellular response to monoamine stimulus	6/2486	34/18670	0.2953	0.5686	0.4457	SIRT2/SNCA/PDE4B/ADCY6/RYR2/SIN3A	6
BP	GO:0071870	cellular response to catecholamine stimulus	6/2486	34/18670	0.2953	0.5686	0.4457	SIRT2/SNCA/PDE4B/ADCY6/RYR2/SIN3A	6
BP	GO:0061337	cardiac conduction	22/2486	146/18670	0.2996	0.5768	0.4521	SRI/SCN1B/ITPR1/CACNA2D2/ATP1B2/CACNB3/GJA5/ASPH/JUP/KCND3/KCNA5/CACNA2D3/FXYD1/NUP155/KCNK3/KCNK6/FKBP1B/ANK2/FLNA/RYR2/CAV1/KCNK1	22
BP	GO:0044782	cilium organization	55/2486	384/18670	0.3	0.5773	0.4525	ABLIM3/TTC17/GAS8/C5orf30/TUB/B9D1/DZIP1L/HSP90AA1/CEP192/WDR11/B9D2/RSPH9/WDR19/WWTR1/NME5/CYLD/FNBP1L/AVIL/CEP135/HAUS8/BBS1/ODF2/SCLT1/NPHP1/TTBK2/PLK1/IFT140/CDKL1/NOTCH1/DYNLRB1/ARMC9/C2CD3/LRRC49/ADAMTS16/FLNA/HAUS2/DZIP1/NDE1/DNALI1/SSNA1/CLASP1/TMEM17/IFT81/DNAH5/INTU/TMEM231/DYNLL2/TMEM67/RAB8A/CCDC113/PRKAR2B/ATXN10/FHDC1/PARVA/NEK2	55
BP	GO:0010955	negative regulation of protein processing	7/2486	41/18670	0.3009	0.5776	0.4527	NOL3/CD59/GAS1/SERPING1/TMEM98/A2M/NLRP7	7
BP	GO:0040019	positive regulation of embryonic development	7/2486	41/18670	0.3009	0.5776	0.4527	HES1/CLASP2/IGF1/SIX1/PLCB1/PHLDB2/CLASP1	7
BP	GO:0097178	ruffle assembly	7/2486	41/18670	0.3009	0.5776	0.4527	EPS8/AIF1L/BAG4/P2RY12/CAV1/PFN1/EPS8L1	7
BP	GO:0098927	vesicle-mediated transport between endosomal compartments	7/2486	41/18670	0.3009	0.5776	0.4527	STX8/SORL1/DAB2/MSN/EMP2/WDR91/CORO1A	7
BP	GO:1901381	positive regulation of potassium ion transmembrane transport	7/2486	41/18670	0.3009	0.5776	0.4527	ATP1B2/MIR21/EDN3/KCNA1/TREM2/ANK2/FLNA	7
BP	GO:1903170	negative regulation of calcium ion transmembrane transport	7/2486	41/18670	0.3009	0.5776	0.4527	SRI/TGFB1/CACNB3/ADRA2A/GPR35/FKBP1B/TLR9	7
BP	GO:1903318	negative regulation of protein maturation	7/2486	41/18670	0.3009	0.5776	0.4527	NOL3/CD59/GAS1/SERPING1/TMEM98/A2M/NLRP7	7
BP	GO:1905209	positive regulation of cardiocyte differentiation	7/2486	41/18670	0.3009	0.5776	0.4527	TBX5/TGFB2/TGFB1/IGF1/EFNB2/MTOR/PIN1	7
BP	GO:0006720	isoprenoid metabolic process	21/2486	139/18670	0.301	0.5776	0.4527	DHRS9/LPL/AGRN/CYP26B1/ABCA4/SDC2/GPC4/EGFR/RARRES2/IDI2/GPIHBP1/GPC6/CRABP1/CYP27C1/ALDH1A3/ALDH1A2/GPC1/HMGCS1/CYP3A5/RBP1/ADH1C	21
BP	GO:0051091	positive regulation of DNA-binding transcription factor activity	38/2486	261/18670	0.3015	0.5776	0.4527	CLU/ANXA3/PPARG/EP300/NFKB2/PRKCB/TNF/BCL10/LTF/DHX9/TGFB1/PINK1/PHB2/TRIM21/UBA52/CX3CL1/PPRC1/ZBTB7A/BTK/DDIT3/TRAF6/JUP/RELA/TNFRSF11A/SMO/RAB7B/NDP/IL1B/UBC/WNT5A/TLR9/ROR1/DDR2/CAV1/HCLS1/TAF1/FZD4/RPS6KA5	38
BP	GO:1903317	regulation of protein maturation	27/2486	182/18670	0.3028	0.5776	0.4527	CLU/PROS1/C1QB/C1QA/C1QC/CR1L/CFH/NOL3/CD59/GAS1/C2/CFB/SERPING1/CFHR2/CPN1/TMEM98/C1R/MYH9/IL1B/RNF139/C1S/CFI/A2M/SPON1/CLEC3B/CCBE1/NLRP7	27
BP	GO:0002438	acute inflammatory response to antigenic stimulus	4/2486	21/18670	0.3034	0.5776	0.4527	ELANE/FCGR2B/BTK/ADCYAP1	4
BP	GO:0014821	phasic smooth muscle contraction	4/2486	21/18670	0.3034	0.5776	0.4527	EDNRB/DLG1/GHRL/EDN3	4
BP	GO:0015874	norepinephrine transport	4/2486	21/18670	0.3034	0.5776	0.4527	SNCA/ADRA2A/P2RY12/OXTR	4
BP	GO:0021697	cerebellar cortex formation	4/2486	21/18670	0.3034	0.5776	0.4527	FAIM2/HERC1/LDB1/AGTPBP1	4
BP	GO:0030502	negative regulation of bone mineralization	4/2486	21/18670	0.3034	0.5776	0.4527	GATA1/BCOR/ECM1/SOX9	4
BP	GO:0032682	negative regulation of chemokine production	4/2486	21/18670	0.3034	0.5776	0.4527	ARG2/ELANE/KLF4/NR1H4	4
BP	GO:0032891	negative regulation of organic acid transport	4/2486	21/18670	0.3034	0.5776	0.4527	CYP4F2/TRH/IRS2/ABAT	4
BP	GO:0035357	peroxisome proliferator activated receptor signaling pathway	4/2486	21/18670	0.3034	0.5776	0.4527	PPARG/TWIST1/FABP5/SIRT1	4
BP	GO:0035590	purinergic nucleotide receptor signaling pathway	4/2486	21/18670	0.3034	0.5776	0.4527	P2RY12/P2RX7/P2RY2/P2RY8	4
BP	GO:0036150	phosphatidylserine acyl-chain remodeling	4/2486	21/18670	0.3034	0.5776	0.4527	PLA2G5/LPCAT4/LPCAT3/PLA2G2A	4
BP	GO:0039531	regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway	4/2486	21/18670	0.3034	0.5776	0.4527	GPATCH3/TSPAN6/RNF125/ZCCHC3	4
BP	GO:0039702	viral budding via host ESCRT complex	4/2486	21/18670	0.3034	0.5776	0.4527	VPS37A/CHMP6/CHMP1B/VPS37B	4
BP	GO:0042438	melanin biosynthetic process	4/2486	21/18670	0.3034	0.5776	0.4527	ASIP/SLC24A5/WNT5A/GIPC1	4
BP	GO:0046716	muscle cell cellular homeostasis	4/2486	21/18670	0.3034	0.5776	0.4527	TGFB1/LOX/MTM1/DMD	4
BP	GO:0051412	response to corticosterone	4/2486	21/18670	0.3034	0.5776	0.4527	FOSB/TRH/CCND1/FOS	4
BP	GO:0060044	negative regulation of cardiac muscle cell proliferation	4/2486	21/18670	0.3034	0.5776	0.4527	MAPK11/TBX5/MIR17HG/JARID2	4
BP	GO:0060713	labyrinthine layer morphogenesis	4/2486	21/18670	0.3034	0.5776	0.4527	RSPO3/FZD5/SPINT2/NCOA1	4
BP	GO:0070584	mitochondrion morphogenesis	4/2486	21/18670	0.3034	0.5776	0.4527	MFF/BCL2L1/MTM1/NUBPL	4
BP	GO:0070920	regulation of production of small RNA involved in gene silencing by RNA	4/2486	21/18670	0.3034	0.5776	0.4527	TGFB1/ZC3H12A/EGFR/ZC3H10	4
BP	GO:0071498	cellular response to fluid shear stress	4/2486	21/18670	0.3034	0.5776	0.4527	MTSS1/ASS1/KLF4/HAS2	4
BP	GO:0090280	positive regulation of calcium ion import	4/2486	21/18670	0.3034	0.5776	0.4527	STC1/CXCL12/RAMP3/PDGFRB	4
BP	GO:1900016	negative regulation of cytokine production involved in inflammatory response	4/2486	21/18670	0.3034	0.5776	0.4527	C5orf30/ADCY7/ZC3H12A/NLRP7	4
BP	GO:1902307	positive regulation of sodium ion transmembrane transport	4/2486	21/18670	0.3034	0.5776	0.4527	ARF1/ATP1B2/FXYD1/DMD	4
BP	GO:1904886	beta-catenin destruction complex disassembly	4/2486	21/18670	0.3034	0.5776	0.4527	APC/CSNK1A1/FZD5/CAV1	4
BP	GO:0031929	TOR signaling	19/2486	125/18670	0.3036	0.5777	0.4528	RRAGA/ARAF/TNFAIP8L1/DEPDC5/PINK1/GAS6/LARP1/FLCN/TELO2/SIRT1/SESN2/SMCR8/SESN3/SIK3/MTM1/TREM2/MAPKAPK5/MTOR/MAPKAP1	19
BP	GO:0032886	regulation of microtubule-based process	32/2486	218/18670	0.3037	0.5779	0.4529	RBM14/FGF13/RASSF1/PARP3/NAV3/CLIP3/APC/SNCA/TRIM58/FKBP4/CLASP2/DIAPH1/NEFH/TPX2/CHMP1B/MDM1/CYLD/SENP6/CDK2AP2/RAE1/PHLDB2/NIN/MAP2/TTBK2/MID1/PLK1/CDK5R1/FAM107A/CDH5/CLASP1/TMEM67/NEK2	32
BP	GO:0007595	lactation	8/2486	48/18670	0.3045	0.5791	0.4539	ATP7B/CDO1/CREB1/CCND1/PAM/OXTR/CAV1/NCOA1	8
BP	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	25/2486	168/18670	0.3062	0.5822	0.4563	ANXA3/ESAM/NEXN/L1CAM/PCDH11X/PCDHB1/PCDH18/CEACAM6/CDH26/CEACAM1/ROBO4/SDK1/PCDHB14/FAT1/PCDH17/CADM3/HMCN1/CDH5/IGSF9/PCDHGC5/IGSF21/PCDHB7/CDH6/CDH11/PCDHGA4	25
BP	GO:0032613	interleukin-10 production	9/2486	55/18670	0.3068	0.5825	0.4565	MMP8/FCGR2B/CD83/IRF4/IL23R/PDCD1LG2/CD34/TREM2/TLR9	9
BP	GO:0042220	response to cocaine	9/2486	55/18670	0.3068	0.5825	0.4565	FADD/SNCA/SDK1/OXTR/HSP90AB1/MTOR/HSPA5/SLC6A1/ABAT	9
BP	GO:0043030	regulation of macrophage activation	9/2486	55/18670	0.3068	0.5825	0.4565	MMP8/SNCA/FCGR2B/CX3CL1/ZC3H12A/IL33/TREM2/WNT5A/PTPRC	9
BP	GO:0006892	post-Golgi vesicle-mediated transport	16/2486	104/18670	0.3068	0.5825	0.4565	SCFD1/VPS13C/ARF1/ARFGEF2/KLHL20/SORL1/SEC16A/BBS1/AP1AR/STEAP2/SNAP23/STX4/SYS1/PKDCC/CCDC93/STXBP6	16
BP	GO:0019233	sensory perception of pain	16/2486	104/18670	0.3068	0.5825	0.4565	MME/EDNRB/FABP5/CACNB3/MGLL/DLG2/P2RX7/UCHL1/CXCL12/KCNA1/NR2F6/NDN/MTOR/ADCYAP1/ITGA2/LXN	16
BP	GO:0006942	regulation of striated muscle contraction	15/2486	97/18670	0.3077	0.5833	0.4572	SRI/FGF13/SMAD7/DLG1/GJA5/ZC3H12A/PDE4B/JUP/STC1/FKBP1B/ANK2/FLNA/RYR2/CAV1/DMD	15
BP	GO:0090630	activation of GTPase activity	15/2486	97/18670	0.3077	0.5833	0.4572	RABGAP1L/NTF3/EIF5/TBC1D10A/CRKL/RALGAPB/TBC1D16/NEDD9/CCL21/ARHGEF16/RANGAP1/WNT5A/TBC1D2B/TBC1D9/RALGAPA2	15
BP	GO:2001022	positive regulation of response to DNA damage stimulus	15/2486	97/18670	0.3077	0.5833	0.4572	PMAIP1/BCLAF1/PARP3/ANKLE1/DHX9/FUS/PARP9/DDX11/SIRT1/EGFR/SKIL/DTX3L/MSX1/MGMT/RNF8	15
BP	GO:0010970	transport along microtubule	24/2486	161/18670	0.3079	0.5833	0.4572	TRAK1/TUB/TRIM58/SFPQ/DYNC1I1/ACTR10/NEFH/DLG2/WDR19/KIF4A/HSPB1/UCHL1/FYCO1/MAP2/TMEM201/WASF1/IFT140/DYNLRB1/SPG7/NDE1/SSNA1/IFT81/DYNLL2/SUN2	24
BP	GO:0099111	microtubule-based transport	24/2486	161/18670	0.3079	0.5833	0.4572	TRAK1/TUB/TRIM58/SFPQ/DYNC1I1/ACTR10/NEFH/DLG2/WDR19/KIF4A/HSPB1/UCHL1/FYCO1/MAP2/TMEM201/WASF1/IFT140/DYNLRB1/SPG7/NDE1/SSNA1/IFT81/DYNLL2/SUN2	24
BP	GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus	10/2486	62/18670	0.3081	0.5833	0.4572	MSH6/POLB/PARP3/TGFB1/EXO1/EXOSC3/BATF/IL2/PTPRC/RNF8	10
BP	GO:0016444	somatic cell DNA recombination	10/2486	62/18670	0.3081	0.5833	0.4572	MSH6/POLB/PARP3/TGFB1/EXO1/EXOSC3/BATF/IL2/PTPRC/RNF8	10
BP	GO:0051898	negative regulation of protein kinase B signaling	10/2486	62/18670	0.3081	0.5833	0.4572	SH2B3/SLC9A3R1/DLG1/PHLDA3/FLCN/SIRT1/DDIT3/KLF4/MTM1/MAGI2	10
BP	GO:1902305	regulation of sodium ion transmembrane transport	10/2486	62/18670	0.3081	0.5833	0.4572	SCN1B/SLC9A3R1/STOM/ARF1/DLG1/ATP1B2/HECW2/UTRN/FXYD1/DMD	10
BP	GO:0000280	nuclear division	58/2486	407/18670	0.3083	0.5835	0.4573	SIRT2/EPS8/APC/AKAP8L/NIPBL/SMC5/CAV2/NCAPG/TGFB1/PHF13/MTBP/PHB2/ANLN/CDKN1C/CLASP2/CYP26B1/CEP192/SMPD3/TPX2/GPR3/CHMP6/CHMP1B/EDN3/SLC2A8/KIF4A/MLH3/UBE2S/CCDC8/HECW2/OBSL1/IGF1/MIS12/EGF/BUB1B/PLCB1/SYCE1/PLK1/PDGFRB/KIF2C/UBE2C/IL1B/WNT5A/FLNA/SIRT7/NDE1/MSX1/DUSP1/AKAP8/TTK/CLASP1/MUS81/PDS5A/CDK13/LRP5/KIF14/MKI67/NEK2/PIN1	58
BP	GO:0001937	negative regulation of endothelial cell proliferation	12/2486	76/18670	0.309	0.5846	0.4582	PPARG/SPARC/CAV2/TNF/FLT1/GHRL/MIR21/VASH1/NR2F2/SULF1/PDCD10/CAV1	12
BP	GO:0034404	nucleobase-containing small molecule biosynthetic process	33/2486	226/18670	0.3113	0.5888	0.4615	NUDT15/SLC4A1/AMD1/NUP93/TDG/PFKFB2/PDE2A/SAMHD1/DHTKD1/ZBTB7A/PDE4B/NUP50/PRTFDC1/NME5/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/VCP/RAE1/NUP188/NUP160/NUP54/NUP214/NUP155/FOXK2/NUPR1/SLC2A6/PRKAG2/TK1/PDE1A/PFKP	33
BP	GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	5/2486	28/18670	0.3139	0.5911	0.4633	SDF2L1/KLHL15/DERL1/VCP/SDF2	5
BP	GO:0006972	hyperosmotic response	5/2486	28/18670	0.3139	0.5911	0.4633	PDPK1/XRCC6/AQP1/RCSD1/EFHD1	5
BP	GO:0007205	protein kinase C-activating G protein-coupled receptor signaling pathway	5/2486	28/18670	0.3139	0.5911	0.4633	PARD3/DGKD/IL2/GAP43/DGKZ	5
BP	GO:0008209	androgen metabolic process	5/2486	28/18670	0.3139	0.5911	0.4633	DHRS9/TIPARP/SPP1/AKR1D1/HSD17B3	5
BP	GO:0009065	glutamine family amino acid catabolic process	5/2486	28/18670	0.3139	0.5911	0.4633	DDAH1/ARG2/ARG1/MIR21/NOS3	5
BP	GO:0031440	regulation of mRNA 3'-end processing	5/2486	28/18670	0.3139	0.5911	0.4633	CPSF7/PAPOLA/CDK9/CPEB1/BARD1	5
BP	GO:0032647	regulation of interferon-alpha production	5/2486	28/18670	0.3139	0.5911	0.4633	LILRA4/DHX9/IFIH1/TLR9/SETD2	5
BP	GO:0042730	fibrinolysis	5/2486	28/18670	0.3139	0.5911	0.4633	PROS1/SERPING1/PLAT/FAP/GP1BA	5
BP	GO:0045408	regulation of interleukin-6 biosynthetic process	5/2486	28/18670	0.3139	0.5911	0.4633	INPP5D/TNF/GHRL/TRAF6/IL1B	5
BP	GO:0045686	negative regulation of glial cell differentiation	5/2486	28/18670	0.3139	0.5911	0.4633	DUSP10/DAAM2/HES1/TMEM98/NOTCH1	5
BP	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway	5/2486	28/18670	0.3139	0.5911	0.4633	LPXN/FCGR2B/CEACAM1/THY1/CD300A	5
BP	GO:0051984	positive regulation of chromosome segregation	5/2486	28/18670	0.3139	0.5911	0.4633	SIRT2/NIPBL/SMC5/SFPQ/DDX11	5
BP	GO:0070861	regulation of protein exit from endoplasmic reticulum	5/2486	28/18670	0.3139	0.5911	0.4633	EDEM1/SORL1/SEC16A/UBE2G2/SLC35D3	5
BP	GO:0086013	membrane repolarization during cardiac muscle cell action potential	5/2486	28/18670	0.3139	0.5911	0.4633	DLG1/KCND3/KCNA5/KCNJ8/FLNA	5
BP	GO:2000108	positive regulation of leukocyte apoptotic process	5/2486	28/18670	0.3139	0.5911	0.4633	SIRT1/P2RX7/PIK3CD/WNT5A/LYN	5
BP	GO:0006302	double-strand break repair	36/2486	248/18670	0.3143	0.5915	0.4636	PSMD14/POLB/XRCC6/YY1/PARP3/NIPBL/SMC5/TWIST1/SFPQ/KLHL15/FUS/SAMHD1/HELB/PARP9/KDM2A/ZBTB7A/DCLRE1A/DDX11/RNF138/TDP2/PML/MTA1/VCP/CDC45/RECQL4/DTX3L/WDR70/UVRAG/TNKS1BP1/PALB2/MUS81/MGMT/BARD1/SETD2/RNF8/MCM5	36
BP	GO:0046434	organophosphate catabolic process	36/2486	248/18670	0.3143	0.5915	0.4636	PLA2G4C/NUDT15/SLC4A1/NUP93/TDG/PFKFB2/PDE2A/SAMHD1/DHTKD1/SMPD3/ZBTB7A/PDE4B/NUP50/APOC1/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/VCP/RAE1/NUP188/NUP160/NUP54/GDPD1/NUP214/NUP155/FOXK2/NUPR1/SLC2A6/PRKAG2/PDE1A/ENPP2/INPP5F/MTMR7/PFKP	36
BP	GO:0006414	translational elongation	20/2486	133/18670	0.3146	0.5919	0.4639	TSFM/EIF5A/MRPL36/MRPL44/MRPL48/RPLP1/MRPL15/MRPL20/MRPS28/EEF1A1/MRPS14/DNAJC24/MRPL18/DIO2/MRPL13/MRPL21/MRPL17/MRPL54/MRPL2/CPEB2	20
BP	GO:0042593	glucose homeostasis	35/2486	241/18670	0.3165	0.5951	0.4665	SRI/LRP5L/SUCNR1/TRA2B/PPARG/CDK16/FABP5/GHRL/RAB11FIP5/C2CD2L/GAS6/ERN1/ADRA2A/RAF1/IGF1R/SIRT1/SESN2/JAGN1/ADIPOR2/GJB6/IRS2/IGFBP5/SESN3/FOXK2/POLG/STX4/FKBP1B/PPP3CB/NOX4/WFS1/UNC13B/PDK4/NR1H4/LRP5/SIN3A	35
BP	GO:0000723	telomere maintenance	24/2486	162/18670	0.3191	0.5978	0.4685	XRCC6/PRIM2/PARP3/RFC1/POLE3/SMC5/HSP90AA1/DCP2/EXO1/TELO2/FBXO4/USP7/POLE/DCLRE1A/PML/PKIB/CCT8/RECQL4/SMG6/HSP90AB1/MAPKAPK5/TNKS1BP1/NHP2/NEK2	24
BP	GO:0042303	molting cycle	17/2486	112/18670	0.3194	0.5978	0.4685	INHBA/NIPBL/TNF/CD109/TGFB2/LDB1/NOM1/EGFR/RELA/IGFBP5/SMO/SOX9/NOTCH1/NSUN2/WNT5A/INTU/PER1	17
BP	GO:0042633	hair cycle	17/2486	112/18670	0.3194	0.5978	0.4685	INHBA/NIPBL/TNF/CD109/TGFB2/LDB1/NOM1/EGFR/RELA/IGFBP5/SMO/SOX9/NOTCH1/NSUN2/WNT5A/INTU/PER1	17
BP	GO:0010959	regulation of metal ion transport	56/2486	394/18670	0.3195	0.5978	0.4685	SRI/SCN1B/SLC9A3R1/PDPK1/STOM/CAMK2G/ARF1/SNCA/DLG1/ATP1B2/TGFB1/FGF14/CACNB3/ADRA2A/DIAPH1/CX3CL1/MIR21/P2RY12/PDE4B/EDN3/STAC/NOS3/STC1/P2RX7/HECW2/MCHR1/GPR35/PML/CXCL12/EGF/STAC2/UTRN/KCNA5/AHNAK/RAMP3/FXYD1/APLNR/PDGFRB/KCNA1/FKBP1B/THY1/TREM2/ANK2/FLNA/TLR9/RYR2/CAV1/STC2/LYN/BAK1/ADCYAP1/DMD/WFS1/PER1/CORO1A/NKAIN1	56
BP	GO:0006369	termination of RNA polymerase II transcription	6/2486	35/18670	0.3199	0.5978	0.4685	CPSF7/PAPOLA/SLBP/PABPN1/SNRPB/PCF11	6
BP	GO:0019433	triglyceride catabolic process	6/2486	35/18670	0.3199	0.5978	0.4685	FABP5/LPL/SORL1/MGLL/CPS1/FABP3	6
BP	GO:0032801	receptor catabolic process	6/2486	35/18670	0.3199	0.5978	0.4685	MYLIP/TGFB1/ITCH/AP2A2/DTX3L/UVRAG	6
BP	GO:0055017	cardiac muscle tissue growth	16/2486	105/18670	0.3208	0.5978	0.4685	YY1/MAPK11/TBX5/TGFB2/AKAP13/SMAD1/FOXC1/IGF1/MIR17HG/TBX2/NOTCH1/YAP1/JARID2/ZFPM2/MTOR/PIN1	16
BP	GO:0007611	learning or memory	37/2486	256/18670	0.3212	0.5978	0.4685	ADCY3/NTAN1/NTF3/FGF13/MME/CLDN5/EP300/BDNF/EIF2AK4/B4GALT2/JUN/CUX2/CREB1/CLN8/FOS/YTHDF1/NFATC4/EGFR/NTRK2/MEIS2/KCNK10/ITGA3/PTN/PLCB1/HRH1/BTG2/PPP3CB/OXTR/NLGN4X/MTOR/RGS14/ARC/PRKAR2B/EPHB2/SLC6A1/SHANK3/LHX8	37
BP	GO:0001829	trophectodermal cell differentiation	3/2486	15/18670	0.3221	0.5978	0.4685	SP3/BYSL/JUNB	3
BP	GO:0001921	positive regulation of receptor recycling	3/2486	15/18670	0.3221	0.5978	0.4685	SNCA/RAMP3/INPP5F	3
BP	GO:0002467	germinal center formation	3/2486	15/18670	0.3221	0.5978	0.4685	TNFAIP3/NFKB2/RC3H1	3
BP	GO:0002483	antigen processing and presentation of endogenous peptide antigen	3/2486	15/18670	0.3221	0.5978	0.4685	HLA-B/IDE/HLA-A	3
BP	GO:0007039	protein catabolic process in the vacuole	3/2486	15/18670	0.3221	0.5978	0.4685	TMEM199/LAPTM4B/CPA2	3
BP	GO:0007512	adult heart development	3/2486	15/18670	0.3221	0.5978	0.4685	MEF2D/APLNR/MYH10	3
BP	GO:0007638	mechanosensory behavior	3/2486	15/18670	0.3221	0.5978	0.4685	SLC1A3/ETV1/SHANK3	3
BP	GO:0009415	response to water	3/2486	15/18670	0.3221	0.5978	0.4685	CD9/COL18A1/LRP11	3
BP	GO:0010759	positive regulation of macrophage chemotaxis	3/2486	15/18670	0.3221	0.5978	0.4685	CSF1/AKIRIN1/RARRES2	3
BP	GO:0014856	skeletal muscle cell proliferation	3/2486	15/18670	0.3221	0.5978	0.4685	AKIRIN1/SIX1/SIX5	3
BP	GO:0014874	response to stimulus involved in regulation of muscle adaptation	3/2486	15/18670	0.3221	0.5978	0.4685	NOL3/UTRN/MTMR4	3
BP	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	3/2486	15/18670	0.3221	0.5978	0.4685	HLA-B/IDE/HLA-A	3
BP	GO:0032486	Rap protein signal transduction	3/2486	15/18670	0.3221	0.5978	0.4685	RAPGEF3/CBL/KIF14	3
BP	GO:0033604	negative regulation of catecholamine secretion	3/2486	15/18670	0.3221	0.5978	0.4685	ADRA2A/P2RY12/ABAT	3
BP	GO:0042362	fat-soluble vitamin biosynthetic process	3/2486	15/18670	0.3221	0.5978	0.4685	TNF/IL1B/PLTP	3
BP	GO:0042754	negative regulation of circadian rhythm	3/2486	15/18670	0.3221	0.5978	0.4685	GHRL/SFPQ/SIN3A	3
BP	GO:0042976	activation of Janus kinase activity	3/2486	15/18670	0.3221	0.5978	0.4685	IL23R/CD300A/GHR	3
BP	GO:0043101	purine-containing compound salvage	3/2486	15/18670	0.3221	0.5978	0.4685	GMPR/PRTFDC1/AMPD2	3
BP	GO:0043584	nose development	3/2486	15/18670	0.3221	0.5978	0.4685	SIX1/ALDH1A3/GLI3	3
BP	GO:0045410	positive regulation of interleukin-6 biosynthetic process	3/2486	15/18670	0.3221	0.5978	0.4685	TNF/TRAF6/IL1B	3
BP	GO:0045475	locomotor rhythm	3/2486	15/18670	0.3221	0.5978	0.4685	MTA1/NCOA2/MTOR	3
BP	GO:0045837	negative regulation of membrane potential	3/2486	15/18670	0.3221	0.5978	0.4685	PMAIP1/PTN/SLC25A27	3
BP	GO:0046184	aldehyde biosynthetic process	3/2486	15/18670	0.3221	0.5978	0.4685	BMP2/REST/DKK3	3
BP	GO:0046321	positive regulation of fatty acid oxidation	3/2486	15/18670	0.3221	0.5978	0.4685	PPARG/TWIST1/IRS2	3
BP	GO:0050651	dermatan sulfate proteoglycan biosynthetic process	3/2486	15/18670	0.3221	0.5978	0.4685	BGN/DCN/CSPG4	3
BP	GO:0050961	detection of temperature stimulus involved in sensory perception	3/2486	15/18670	0.3221	0.5978	0.4685	CXCL12/NR2F6/LXN	3
BP	GO:0050965	detection of temperature stimulus involved in sensory perception of pain	3/2486	15/18670	0.3221	0.5978	0.4685	CXCL12/NR2F6/LXN	3
BP	GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	3/2486	15/18670	0.3221	0.5978	0.4685	SRI/TGFB1/FKBP1B	3
BP	GO:0060026	convergent extension	3/2486	15/18670	0.3221	0.5978	0.4685	SFRP2/SFRP1/WNT5A	3
BP	GO:0060841	venous blood vessel development	3/2486	15/18670	0.3221	0.5978	0.4685	EFNB2/NOTCH1/CCBE1	3
BP	GO:0072160	nephron tubule epithelial cell differentiation	3/2486	15/18670	0.3221	0.5978	0.4685	WWTR1/MTSS1/YAP1	3
BP	GO:0098840	protein transport along microtubule	3/2486	15/18670	0.3221	0.5978	0.4685	SFPQ/DLG2/HSPB1	3
BP	GO:0099118	microtubule-based protein transport	3/2486	15/18670	0.3221	0.5978	0.4685	SFPQ/DLG2/HSPB1	3
BP	GO:1902548	negative regulation of cellular response to vascular endothelial growth factor stimulus	3/2486	15/18670	0.3221	0.5978	0.4685	SPRY2/DCN/ADAMTS12	3
BP	GO:1903729	regulation of plasma membrane organization	3/2486	15/18670	0.3221	0.5978	0.4685	SYTL4/TGFB2/MYH9	3
BP	GO:0042472	inner ear morphogenesis	15/2486	98/18670	0.3222	0.5978	0.4685	SPRY2/SLC9A3R1/FOXI1/SOBP/SIX1/SEC24B/PRRX1/SOX9/ALDH1A3/CTHRC1/WNT5A/LRIG3/TBX1/EPHB2/MYO15A	15
BP	GO:0051592	response to calcium ion	22/2486	148/18670	0.3231	0.5984	0.469	SUCNR1/PEF1/JUND/FOSB/SPARC/JUN/FUS/CCND1/FOS/EGFR/P2RX7/KCNMA1/S100A16/WNT5A/RYR2/DUSP1/CAV1/HSPA5/JUNB/SLC6A1/SYT11/GDI1	22
BP	GO:0002639	positive regulation of immunoglobulin production	7/2486	42/18670	0.3234	0.5984	0.469	TGFB1/EXOSC3/IL2/STX4/IL33/TLR9/PTPRC	7
BP	GO:0021983	pituitary gland development	7/2486	42/18670	0.3234	0.5984	0.469	CREB1/HES1/BMP2/ALDH1A2/WNT5A/MSX1/ADCYAP1	7
BP	GO:0031057	negative regulation of histone modification	7/2486	42/18670	0.3234	0.5984	0.469	BCOR/SNCA/TWIST1/SIRT1/JARID2/SET/SIN3A	7
BP	GO:0032958	inositol phosphate biosynthetic process	7/2486	42/18670	0.3234	0.5984	0.469	SNCA/CD244/PLCB2/PTH1R/PLCB1/HRH1/PLCD4	7
BP	GO:0033003	regulation of mast cell activation	7/2486	42/18670	0.3234	0.5984	0.469	PDPK1/STXBP1/C12orf4/IL13RA2/CD300LF/CD300A/LYN	7
BP	GO:0042149	cellular response to glucose starvation	7/2486	42/18670	0.3234	0.5984	0.469	PMAIP1/IFI16/ZC3H12A/SESN2/TBL2/SESN3/HSPA5	7
BP	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	7/2486	42/18670	0.3234	0.5984	0.469	CNOT8/ISG20L2/DCP2/ZC3H12A/EXOSC3/CNOT7/CNOT1	7
BP	GO:1901031	regulation of response to reactive oxygen species	7/2486	42/18670	0.3234	0.5984	0.469	TNF/PINK1/MIR21/PYCR1/SESN2/GCH1/SESN3	7
BP	GO:0046390	ribose phosphate biosynthetic process	43/2486	300/18670	0.325	0.6002	0.4704	ADCY3/PDPR/GUCY2D/SLC4A1/SNCA/ADCY7/NUP93/TGFB1/PINK1/ADCY4/PFKFB2/LDHC/DHTKD1/FLCN/ZBTB7A/NUP50/NME5/ADCY6/P2RX7/CBFA2T3/IGF1/NUP153/NUP210/ELOVL7/VCP/RAE1/NUP188/NUP160/NUP54/PDP1/NUP214/NUP155/FOXK2/AMPD2/NUPR1/SLC2A6/PRKAG2/TREM2/PFAS/PANK1/PDK4/ELOVL5/PFKP	43
BP	GO:0003254	regulation of membrane depolarization	8/2486	49/18670	0.3253	0.6002	0.4704	SCN1B/PPP2R3C/SMAD7/GJA5/P2RX7/IFI6/DCN/KDR	8
BP	GO:0051205	protein insertion into membrane	8/2486	49/18670	0.3253	0.6002	0.4704	PMAIP1/MOAP1/RTP4/EGFR/YWHAZ/UBL4A/BMF/TP53BP2	8
BP	GO:0051445	regulation of meiotic cell cycle	8/2486	49/18670	0.3253	0.6002	0.4704	SIRT2/YTHDF2/GPR3/PLCB1/WNT5A/MSX1/DUSP1/TTK	8
BP	GO:0071349	cellular response to interleukin-12	8/2486	49/18670	0.3253	0.6002	0.4704	ARF1/CA1/JAK1/MSN/PLCB1/IL12A/CAPZA1/HSPA9	8
BP	GO:0071825	protein-lipid complex subunit organization	8/2486	49/18670	0.3253	0.6002	0.4704	ARF1/LPL/APOC1/GPIHBP1/AGTR1/PLAGL2/PLA2G2A/PLTP	8
BP	GO:0035050	embryonic heart tube development	12/2486	77/18670	0.3255	0.6002	0.4704	ACVR1/HES1/GJA5/FOXC1/SMO/TBX2/NOTCH1/YAP1/C2CD3/WNT5A/RYR2/TBX1	12
BP	GO:2000779	regulation of double-strand break repair	12/2486	77/18670	0.3255	0.6002	0.4704	PARP3/TWIST1/KLHL15/FUS/HELB/PARP9/DDX11/PML/DTX3L/WDR70/MGMT/SETD2	12
BP	GO:0033500	carbohydrate homeostasis	35/2486	242/18670	0.3257	0.6002	0.4704	SRI/LRP5L/SUCNR1/TRA2B/PPARG/CDK16/FABP5/GHRL/RAB11FIP5/C2CD2L/GAS6/ERN1/ADRA2A/RAF1/IGF1R/SIRT1/SESN2/JAGN1/ADIPOR2/GJB6/IRS2/IGFBP5/SESN3/FOXK2/POLG/STX4/FKBP1B/PPP3CB/NOX4/WFS1/UNC13B/PDK4/NR1H4/LRP5/SIN3A	35
BP	GO:0006901	vesicle coating	11/2486	70/18670	0.3261	0.6002	0.4704	TRAPPC10/SCFD1/PEF1/CNIH3/CD59/TFG/SEC16A/F8/BET1/SEC24B/ARFGAP2	11
BP	GO:0050766	positive regulation of phagocytosis	11/2486	70/18670	0.3261	0.6002	0.4704	PPARG/TUB/TNF/C2/GAS6/FCGR2B/IL1B/CD300LF/TREM2/ITGA2/PTPRC	11
BP	GO:2001259	positive regulation of cation channel activity	11/2486	70/18670	0.3261	0.6002	0.4704	PINK1/FGF14/CACNB3/STAC/STAC2/KCNA1/TREM2/ANK2/ARC/EPHB2/SHANK3	11
BP	GO:0000768	syncytium formation by plasma membrane fusion	9/2486	56/18670	0.3262	0.6002	0.4704	CD9/CD109/PTGFRN/RAPGEF3/EHD2/CDON/MYH9/TREM2/FER1L5	9
BP	GO:0031295	T cell costimulation	9/2486	56/18670	0.3262	0.6002	0.4704	PDPK1/VAV1/PDCD1LG2/EFNB2/TNFRSF14/CCL21/PAK3/CAV1/LYN	9
BP	GO:0032615	interleukin-12 production	9/2486	56/18670	0.3262	0.6002	0.4704	IRF8/MAPK11/IRF1/TRAF6/IL23R/RELA/PLCB1/ACP5/TLR9	9
BP	GO:0140253	cell-cell fusion	9/2486	56/18670	0.3262	0.6002	0.4704	CD9/CD109/PTGFRN/RAPGEF3/EHD2/CDON/MYH9/TREM2/FER1L5	9
BP	GO:1903202	negative regulation of oxidative stress-induced cell death	9/2486	56/18670	0.3262	0.6002	0.4704	NOL3/PINK1/MIR21/PYCR1/SIRT1/NME5/HSPB1/REST/NONO	9
BP	GO:0007062	sister chromatid cohesion	10/2486	63/18670	0.3264	0.6002	0.4704	STAG3L4/NIPBL/SMC5/SFPQ/PHB2/FBXW7/DDX11/BUB1B/PLK1/PDS5A	10
BP	GO:0031646	positive regulation of neurological system process	10/2486	63/18670	0.3264	0.6002	0.4704	WASF3/PARD3/CUX2/SSH1/CACNB3/MTOR/ITGA2/UNC13B/SHANK3/ABAT	10
BP	GO:0035418	protein localization to synapse	10/2486	63/18670	0.3264	0.6002	0.4704	GRIP1/DLG1/DLG2/GRIP2/GPC4/HSPB1/GPC6/GRASP/WNT5A/RAB8A	10
BP	GO:0042255	ribosome assembly	10/2486	63/18670	0.3264	0.6002	0.4704	RPS27/RPS28/RPS27L/RPS15/MRPL20/RPL10/EIF2A/RSL24D1/RPS10/RPL6	10
BP	GO:0032368	regulation of lipid transport	19/2486	127/18670	0.3291	0.605	0.4742	ITGB3/PPARG/NFKBIA/GHRL/CYP4F2/APOC1/SIRT1/SPP1/P2RX7/EGF/TNFRSF11A/HNRNPK/IRS2/AGTR1/C1QTNF1/IL1B/TRIAP1/PLTP/FABP3	19
BP	GO:0002440	production of molecular mediator of immune response	41/2486	286/18670	0.3296	0.6058	0.4748	MSH6/POLB/PARP3/ARG1/TRIM6/TNF/SMAD7/DLG1/BCL10/TGFB2/IL1R1/CD244/TGFB1/ELANE/SAMHD1/GAS6/FCGR2B/DDX21/EXO1/BTK/SIRT1/EXOSC3/TRAF6/BATF/IL13RA2/IL12A/IL2/TNFRSF14/MCM3AP/GAPT/IL1B/STX4/IL33/FZD5/WNT5A/TLR9/POU2F2/TRIL/PTPRC/RSAD2/RNF8	41
BP	GO:0006732	coenzyme metabolic process	57/2486	403/18670	0.3318	0.6096	0.4778	PPTC7/PDPR/GNMT/ME1/SLC4A1/AMD1/SNCA/NUP93/CYP4F2/PFKFB2/COQ10B/DHTKD1/PARP9/ZBTB7A/NUP50/OXSM/GCH1/NNMT/QPRT/P2RX7/PTS/CBFA2T3/IGF1/NUP153/LIAS/NUP210/ACOT13/ELOVL7/VCP/RAE1/NUP188/NUP160/NUP54/CBR3/PDP1/NADSYN1/NUP214/NUP155/FOXK2/PDZD11/NUPR1/AADAT/SLC2A6/PRKAG2/TPK1/SLC23A1/ALDH1L2/HMGCS1/PANK1/MAT2A/PDK4/NMNAT3/RPIA/ELOVL5/MTHFR/HMGCL/PFKP	57
BP	GO:0044272	sulfur compound biosynthetic process	28/2486	192/18670	0.3321	0.6101	0.4781	PDPR/CHST1/AMD1/B4GALT2/SNCA/CDO1/GGT5/MIR21/GSTT1/LIAS/ELOVL7/CHST3/BGN/PDP1/GSTM5/TPK1/DCN/ACAN/OGN/HPGDS/MAT2A/CSPG4/FMOD/PRELP/PDK4/B4GALT4/ELOVL5/MTHFR	28
BP	GO:0007259	JAK-STAT cascade	23/2486	156/18670	0.3327	0.6108	0.4787	SH2B3/TNF/PPP2CA/HES1/CRLF1/PARP9/IL23R/IGF1/EGF/IL12A/IL2/NOTCH1/CRLF3/IL26/CD300A/CNOT7/CAV1/HCLS1/INPP5F/IL10RA/LYN/GHR/PTPRC	23
BP	GO:0043535	regulation of blood vessel endothelial cell migration	23/2486	156/18670	0.3327	0.6108	0.4787	PDPK1/PPARG/VEGFC/TGFB1/NRP1/FBXW7/FGF18/MMRN2/SIRT1/JUP/NOS3/HSPB1/CARD10/VASH1/RHOJ/SRPX2/MEOX2/KLF4/NOTCH1/ANGPT2/PDCD10/MAP3K3/KDR	23
BP	GO:0015893	drug transport	31/2486	214/18670	0.3351	0.6122	0.4798	HBB/SLC15A4/SLC35F3/HBD/SLC18A1/SLC6A8/ARG1/INHBA/SLC25A5/SNCA/GHRL/SLC1A3/NFKBIE/PINK1/CYGB/LMBRD1/HBM/CLN8/CXCL12/SLC25A6/OSCP1/SLC1A1/SLC26A6/SLC7A3/AQP1/SLC32A1/HBQ1/FZD4/SLC25A29/SYT11/ABAT	31
BP	GO:0006582	melanin metabolic process	4/2486	22/18670	0.3354	0.6122	0.4798	ASIP/SLC24A5/WNT5A/GIPC1	4
BP	GO:0007063	regulation of sister chromatid cohesion	4/2486	22/18670	0.3354	0.6122	0.4798	NIPBL/SMC5/SFPQ/DDX11	4
BP	GO:0021513	spinal cord dorsal/ventral patterning	4/2486	22/18670	0.3354	0.6122	0.4798	DMRT3/SMO/GLI3/INTU	4
BP	GO:0032069	regulation of nuclease activity	4/2486	22/18670	0.3354	0.6122	0.4798	TCEA1/DDX11/SIRT1/ABCE1	4
BP	GO:0032727	positive regulation of interferon-alpha production	4/2486	22/18670	0.3354	0.6122	0.4798	DHX9/IFIH1/TLR9/SETD2	4
BP	GO:0032928	regulation of superoxide anion generation	4/2486	22/18670	0.3354	0.6122	0.4798	CD177/TGFB1/EGFR/ACP5	4
BP	GO:0034643	establishment of mitochondrion localization, microtubule-mediated	4/2486	22/18670	0.3354	0.6122	0.4798	TRAK1/ACTR10/UCHL1/WASF1	4
BP	GO:0035809	regulation of urine volume	4/2486	22/18670	0.3354	0.6122	0.4798	EDNRB/SLC4A1/ADCY6/HAS2	4
BP	GO:0042094	interleukin-2 biosynthetic process	4/2486	22/18670	0.3354	0.6122	0.4798	ZFP36/IRF4/IL1B/PTPRC	4
BP	GO:0043496	regulation of protein homodimerization activity	4/2486	22/18670	0.3354	0.6122	0.4798	ITGA4/TRAF4/BAK1/HSPA5	4
BP	GO:0045624	positive regulation of T-helper cell differentiation	4/2486	22/18670	0.3354	0.6122	0.4798	MIR21/NFKBIZ/HLX/IL23R	4
BP	GO:0046628	positive regulation of insulin receptor signaling pathway	4/2486	22/18670	0.3354	0.6122	0.4798	SORL1/SIRT1/SORBS1/NR1H4	4
BP	GO:0047497	mitochondrion transport along microtubule	4/2486	22/18670	0.3354	0.6122	0.4798	TRAK1/ACTR10/UCHL1/WASF1	4
BP	GO:0051195	negative regulation of cofactor metabolic process	4/2486	22/18670	0.3354	0.6122	0.4798	CBFA2T3/HP/MMP3/NUPR1	4
BP	GO:0060547	negative regulation of necrotic cell death	4/2486	22/18670	0.3354	0.6122	0.4798	FADD/NOL3/MIR214/CAV1	4
BP	GO:0071404	cellular response to low-density lipoprotein particle stimulus	4/2486	22/18670	0.3354	0.6122	0.4798	PPARG/CD9/LPL/HMGCS1	4
BP	GO:1901798	positive regulation of signal transduction by p53 class mediator	4/2486	22/18670	0.3354	0.6122	0.4798	PMAIP1/MSX1/CHD5/RPS7	4
BP	GO:1904666	regulation of ubiquitin protein ligase activity	4/2486	22/18670	0.3354	0.6122	0.4798	UBE2S/PLK1/UBE2C/RPS7	4
BP	GO:0060359	response to ammonium ion	20/2486	135/18670	0.3397	0.6199	0.4859	MAP1LC3A/FOSB/FADD/SNCA/CRKL/AGRN/DIAPH1/RELA/ASS1/PLCB1/SDK1/HRH1/CDK5R1/OXTR/HSP90AB1/MTOR/HSPA5/SLC6A1/SIN3A/ABAT	20
BP	GO:0008202	steroid metabolic process	47/2486	331/18670	0.3401	0.6206	0.4864	OSBP/CYP11A1/MBTPS1/OSBPL6/DHRS9/LIPA/PBX1/TNF/HSD3B7/APOF/SULT4A1/CH25H/SORL1/TIPARP/CYP26B1/ERLIN1/NFYA/BMP2/CLN8/APOC1/CYP21A2/SIRT1/SPP1/HSD11B2/ACAT2/ERLIN2/HSD17B14/OSBPL9/HSD11B1/GNB3/IDI2/PDGFRA/HSD17B1/AKR1C2/AGTR1/PRKAG2/IL1B/REST/AKR1D1/HMGCS1/CYP3A5/EBPL/HSD17B3/CYP39A1/DKK3/NR1H4/NR5A2	47
BP	GO:0034308	primary alcohol metabolic process	13/2486	85/18670	0.3405	0.6208	0.4866	CYP11A1/DHRS9/BMP2/NAAA/IGF1/AKR1C2/GDPD1/CYP27C1/ALDH1A3/ALDH1A2/REST/DKK3/ADH1C	13
BP	GO:0045682	regulation of epidermis development	13/2486	85/18670	0.3405	0.6208	0.4866	NCOA3/KEAP1/TNF/CD109/HOXA7/TGFB2/ZFP36/HES1/FOXC1/SFRP4/SMO/NOTCH1/WNT5A	13
BP	GO:0010954	positive regulation of protein processing	5/2486	29/18670	0.3417	0.6213	0.4869	MYH9/IL1B/SPON1/CLEC3B/CCBE1	5
BP	GO:0031063	regulation of histone deacetylation	5/2486	29/18670	0.3417	0.6213	0.4869	AKAP8L/NIPBL/TGFB1/PINK1/AKAP8	5
BP	GO:0035666	TRIF-dependent toll-like receptor signaling pathway	5/2486	29/18670	0.3417	0.6213	0.4869	FADD/UBA52/CD300LF/UBC/UBE2D3	5
BP	GO:0044550	secondary metabolite biosynthetic process	5/2486	29/18670	0.3417	0.6213	0.4869	ASIP/MIR21/SLC24A5/WNT5A/GIPC1	5
BP	GO:0048240	sperm capacitation	5/2486	29/18670	0.3417	0.6213	0.4869	CABYR/CATSPER3/SLC26A6/SLC26A8/DEFB1	5
BP	GO:0051642	centrosome localization	5/2486	29/18670	0.3417	0.6213	0.4869	PARD3/DLG1/NIN/NDE1/SUN2	5
BP	GO:1900027	regulation of ruffle assembly	5/2486	29/18670	0.3417	0.6213	0.4869	EPS8/P2RY12/CAV1/PFN1/EPS8L1	5
BP	GO:1902624	positive regulation of neutrophil migration	5/2486	29/18670	0.3417	0.6213	0.4869	IL1R1/THBS4/DAPK2/CCL21/XG	5
BP	GO:1990126	retrograde transport, endosome to plasma membrane	5/2486	29/18670	0.3417	0.6213	0.4869	GRIP1/GRIP2/GRASP/RAB8A/CCDC93	5
BP	GO:2000727	positive regulation of cardiac muscle cell differentiation	5/2486	29/18670	0.3417	0.6213	0.4869	TGFB1/IGF1/EFNB2/MTOR/PIN1	5
BP	GO:0000271	polysaccharide biosynthetic process	12/2486	78/18670	0.3421	0.6215	0.4871	TGFB1/SMPD3/UGP2/IGF1/EGF/IRS2/HAS2/SORBS1/HAS3/HAS1/MTOR/PPP1R3C	12
BP	GO:0055021	regulation of cardiac muscle tissue growth	12/2486	78/18670	0.3421	0.6215	0.4871	YY1/MAPK11/TBX5/IGF1/MIR17HG/TBX2/NOTCH1/YAP1/JARID2/ZFPM2/MTOR/PIN1	12
BP	GO:0072347	response to anesthetic	12/2486	78/18670	0.3421	0.6215	0.4871	MAP1LC3A/FOSB/FADD/SNCA/RELA/SDK1/OXTR/HSP90AB1/MTOR/HSPA5/SLC6A1/ABAT	12
BP	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	11/2486	71/18670	0.3436	0.6237	0.4889	TNF/HES1/CRLF1/PARP9/IL23R/IGF1/IL12A/IL2/HCLS1/LYN/GHR	11
BP	GO:0043271	negative regulation of ion transport	23/2486	157/18670	0.3445	0.6237	0.4889	SRI/SLC9A3R1/SNCA/TWIST1/TGFB1/CYP4F2/TRH/CACNB3/ADRA2A/NOS3/STC1/HECW2/GPR35/MMP9/IRS2/SFRP4/FKBP1B/TLR9/CAV1/MTOR/ADCYAP1/EPHB2/ABAT	23
BP	GO:0000578	embryonic axis specification	6/2486	36/18670	0.3448	0.6237	0.4889	PCSK6/HOXD8/FRS2/C2CD3/FZD5/WNT5A	6
BP	GO:0014808	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	6/2486	36/18670	0.3448	0.6237	0.4889	SRI/NOL3/FKBP1B/ANK2/RYR2/DMD	6
BP	GO:0045740	positive regulation of DNA replication	6/2486	36/18670	0.3448	0.6237	0.4889	JUN/DHX9/EGFR/DBF4/TNFAIP1/E2F8	6
BP	GO:0051973	positive regulation of telomerase activity	6/2486	36/18670	0.3448	0.6237	0.4889	HSP90AA1/PKIB/KLF4/HSP90AB1/MAPKAPK5/NEK2	6
BP	GO:0071392	cellular response to estradiol stimulus	6/2486	36/18670	0.3448	0.6237	0.4889	NCOA3/EGFR/RAMP3/POU4F1/SFRP1/ITGA2	6
BP	GO:0090313	regulation of protein targeting to membrane	6/2486	36/18670	0.3448	0.6237	0.4889	STOM/MFF/CACNB3/MYO1C/CDK5R1/GDI1	6
BP	GO:1901020	negative regulation of calcium ion transmembrane transporter activity	6/2486	36/18670	0.3448	0.6237	0.4889	SRI/CACNB3/ADRA2A/GPR35/FKBP1B/TLR9	6
BP	GO:1902622	regulation of neutrophil migration	6/2486	36/18670	0.3448	0.6237	0.4889	IL1R1/THBS4/DAPK2/CCL21/SLIT2/XG	6
BP	GO:2000310	regulation of NMDA receptor activity	6/2486	36/18670	0.3448	0.6237	0.4889	ANXA3/DLG1/PINK1/DLG2/GRIA3/EPHB2	6
BP	GO:2001171	positive regulation of ATP biosynthetic process	6/2486	36/18670	0.3448	0.6237	0.4889	PINK1/PFKFB2/P2RX7/IGF1/VCP/TREM2	6
BP	GO:0036498	IRE1-mediated unfolded protein response	10/2486	64/18670	0.3449	0.6237	0.4889	EDEM1/SERP1/HYOU1/ERN1/SSR1/DDX11/KDELR3/BAK1/WFS1/HSPA5	10
BP	GO:0048247	lymphocyte chemotaxis	10/2486	64/18670	0.3449	0.6237	0.4889	HSD3B7/CH25H/GAS6/CX3CL1/CCL13/PIK3CD/CCL21/WNT5A/CCL8/CCL18	10
BP	GO:2000378	negative regulation of reactive oxygen species metabolic process	10/2486	64/18670	0.3449	0.6237	0.4889	SIRT2/PINK1/MIR21/ZC3H12A/HP/MMP3/CD34/ACP5/CAV1/CRYAB	10
BP	GO:0007029	endoplasmic reticulum organization	9/2486	57/18670	0.3458	0.6238	0.4889	TMEM170A/CAV2/ATL2/RAB3GAP2/JAGN1/SEC16A/UBL4A/LMAN1L/BNIP1	9
BP	GO:0031294	lymphocyte costimulation	9/2486	57/18670	0.3458	0.6238	0.4889	PDPK1/VAV1/PDCD1LG2/EFNB2/TNFRSF14/CCL21/PAK3/CAV1/LYN	9
BP	GO:1900408	negative regulation of cellular response to oxidative stress	9/2486	57/18670	0.3458	0.6238	0.4889	NOL3/PINK1/MIR21/PYCR1/SIRT1/NME5/HSPB1/REST/NONO	9
BP	GO:0006692	prostanoid metabolic process	7/2486	43/18670	0.3461	0.6238	0.4889	HPGD/FABP5/SIRT1/AKR1C2/IL1B/HPGDS/PTGR1	7
BP	GO:0006693	prostaglandin metabolic process	7/2486	43/18670	0.3461	0.6238	0.4889	HPGD/FABP5/SIRT1/AKR1C2/IL1B/HPGDS/PTGR1	7
BP	GO:0032924	activin receptor signaling pathway	7/2486	43/18670	0.3461	0.6238	0.4889	ACVR1/INHBA/SMAD7/ACVR2A/TGIF2/DACT2/MAGI2	7
BP	GO:0046461	neutral lipid catabolic process	7/2486	43/18670	0.3461	0.6238	0.4889	DAGLB/FABP5/LPL/SORL1/MGLL/CPS1/FABP3	7
BP	GO:0046464	acylglycerol catabolic process	7/2486	43/18670	0.3461	0.6238	0.4889	DAGLB/FABP5/LPL/SORL1/MGLL/CPS1/FABP3	7
BP	GO:0009948	anterior/posterior axis specification	8/2486	50/18670	0.3463	0.6238	0.4889	LDB1/PCSK6/DDIT3/HOXD8/FRS2/FZD5/WNT5A/SIX2	8
BP	GO:0032784	regulation of DNA-templated transcription, elongation	8/2486	50/18670	0.3463	0.6238	0.4889	TSFM/CDK9/LDB1/CCNT2/POU4F1/ELL/CDK13/RNF8	8
BP	GO:0060425	lung morphogenesis	8/2486	50/18670	0.3463	0.6238	0.4889	SPRY2/TNF/SPRY1/NFIB/SEC24B/SOX9/YAP1/TNC	8
BP	GO:0070534	protein K63-linked ubiquitination	8/2486	50/18670	0.3463	0.6238	0.4889	ARIH2/ITCH/TRAF6/UBE2S/HECTD1/MAGEL2/ZFP91/RNF8	8
BP	GO:0070671	response to interleukin-12	8/2486	50/18670	0.3463	0.6238	0.4889	ARF1/CA1/JAK1/MSN/PLCB1/IL12A/CAPZA1/HSPA9	8
BP	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	8/2486	50/18670	0.3463	0.6238	0.4889	MTBP/CCND1/EGFR/PLCB1/CDC45/KCNA5/MIR214/HYAL1	8
BP	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	15/2486	100/18670	0.3517	0.6331	0.4962	SLC9A3R1/EDNRB/LPAR6/TACR1/ADRA2A/P2RY12/GPR4/LPAR4/GPR35/PTH1R/P2RY2/AGTR1/HRH1/P2RY8/GNA14	15
BP	GO:0010657	muscle cell apoptotic process	15/2486	100/18670	0.3517	0.6331	0.4962	PDPK1/PPARG/NOL3/MIR21/ZC3H12A/SIRT1/SFRP2/MAP3K5/IGF1/STK4/IL12A/NUPR1/PDE1A/HSPB6/ADCYAP1	15
CC	GO:0062023	collagen-containing extracellular matrix	146/2573	406/19717	1.406e-32	1.042e-29	8.701e-30	CLU/C1QB/C1QA/COL9A2/LTBP1/SLPI/C1QC/ORM1/ADAMTS2/COCH/MMP8/CTSG/HTRA1/SEMA3B/SPARC/TGM4/LGALS3BP/NAV2/COL6A1/HSP90B1/DLG1/TGFB2/LAMC1/WNT5B/TNXB/TGFB1/HNRNPM/AGRN/ELANE/VWF/PXDN/BCAM/L1CAM/PCSK6/EFEMP2/COL10A1/TPSAB1/FN1/COL16A1/EGFL7/ZP1/SCARA3/SDC2/GPC4/LAMC2/FBN2/COL18A1/MMRN2/THBS4/SERPING1/ELN/ECM1/RARRES2/SFRP2/SERPINH1/NPNT/KAZALD1/MMRN1/NID2/CCDC80/SMOC2/CXCL12/ADAMTS9/PCOLCE/COL27A1/PTN/COL4A1/LOXL1/F13A1/COL4A2/GPC6/BGN/ADAMTS15/MMP9/INHBE/TGFB1I1/TIMP3/SRPX2/LMAN1L/SULF1/COL14A1/DPT/CDON/THBS3/ECM2/PRG4/MFAP2/SERPINB9/SPARCL1/COL5A1/NDP/SMOC1/TINAGL1/LTBP2/SERPINA3/HAPLN1/CLEC14A/MXRA5/CTHRC1/MATN2/EMILIN3/SFRP1/ANGPTL2/MUC2/GPC1/LAMB1/ASPN/SSC5D/VIT/LRRC15/COL12A1/COL21A1/FBLN1/WNT5A/DCN/EFEMP1/HMCN1/MFAP5/CTSF/ACAN/OGN/CILP/VWA1/CSPG4/NTN4/COL6A2/COL17A1/ITIH2/POSTN/EDIL3/FBN1/MST1/SOD3/FMOD/A2M/SPON1/MFAP4/PRELP/MGP/TNC/LTBP4/FBLN2/COL5A2/CLEC3B/COL1A2/CD151	146
CC	GO:0030055	cell-substrate junction	108/2573	412/19717	3.531e-13	1.308e-10	1.093e-10	ITGB3/LPXN/TRIP6/CTTN/TNS1/TSPAN9/AIF1L/ITGB5/PDPK1/MME/TES/FHL2/ITGA4/ARF1/HSP90B1/PRKAR2A/CD9/CAV2/FLT1/LIMS2/DCAF6/CD59/STX16/FBLIM1/PDIA3/RPS15/HYOU1/NEXN/NRP1/L1CAM/CLASP2/ASAP3/RPLP1/RPS3A/MRC2/DAB2/ARHGEF7/JUP/EGFR/JAK1/HSPB1/SPRY4/ITGA3/MSN/YWHAZ/RND3/FLRT2/PAK4/HNRNPK/RPS8/CBL/PHLDB2/TGFB1I1/RPS2/FERMT2/RPS10/AHNAK/EFNB2/NUP214/ACTN1/WASF1/FAT1/BCAR1/ENAH/PDGFRB/RPL6/SNAP23/CIB2/MYH9/FLNC/TEK/NEDD9/FAP/SORBS1/THY1/MCAM/LIMS1/NCKAP1/ITGB8/CSRP2/NOX4/FAM107A/USP33/FLNA/ARPC2/DDR2/CAV1/ITGBL1/CSPG4/RPS7/COL17A1/CLASP1/DLC1/GIT2/ITGA2/DMD/CSRP1/PCBP2/PFN1/HSPA5/TNC/DCTN4/PTPRC/PARVA/RPL9/HSPA9/ZFYVE21/CD151	108
CC	GO:0005924	cell-substrate adherens junction	106/2573	408/19717	1.075e-12	2.655e-10	2.218e-10	ITGB3/LPXN/TRIP6/CTTN/TNS1/TSPAN9/AIF1L/ITGB5/PDPK1/MME/TES/FHL2/ITGA4/ARF1/HSP90B1/PRKAR2A/CD9/CAV2/FLT1/LIMS2/DCAF6/CD59/STX16/FBLIM1/PDIA3/RPS15/HYOU1/NEXN/NRP1/L1CAM/CLASP2/ASAP3/RPLP1/RPS3A/MRC2/DAB2/ARHGEF7/JUP/EGFR/JAK1/HSPB1/SPRY4/ITGA3/MSN/YWHAZ/RND3/FLRT2/PAK4/HNRNPK/RPS8/CBL/PHLDB2/TGFB1I1/RPS2/FERMT2/RPS10/AHNAK/EFNB2/NUP214/ACTN1/WASF1/FAT1/BCAR1/ENAH/PDGFRB/RPL6/SNAP23/CIB2/MYH9/FLNC/TEK/NEDD9/FAP/SORBS1/THY1/MCAM/LIMS1/NCKAP1/ITGB8/CSRP2/NOX4/FAM107A/USP33/FLNA/ARPC2/DDR2/CAV1/ITGBL1/CSPG4/RPS7/CLASP1/DLC1/GIT2/ITGA2/CSRP1/PCBP2/PFN1/HSPA5/TNC/DCTN4/PTPRC/PARVA/RPL9/HSPA9/ZFYVE21/CD151	106
CC	GO:0005925	focal adhesion	105/2573	405/19717	1.583e-12	2.933e-10	2.45e-10	ITGB3/LPXN/TRIP6/CTTN/TNS1/TSPAN9/AIF1L/ITGB5/PDPK1/MME/TES/FHL2/ITGA4/ARF1/HSP90B1/PRKAR2A/CD9/CAV2/FLT1/LIMS2/DCAF6/CD59/STX16/FBLIM1/PDIA3/RPS15/HYOU1/NEXN/NRP1/L1CAM/CLASP2/ASAP3/RPLP1/RPS3A/MRC2/DAB2/ARHGEF7/JUP/EGFR/JAK1/HSPB1/SPRY4/ITGA3/MSN/YWHAZ/RND3/FLRT2/PAK4/HNRNPK/RPS8/CBL/PHLDB2/TGFB1I1/RPS2/FERMT2/RPS10/AHNAK/EFNB2/NUP214/ACTN1/WASF1/FAT1/BCAR1/ENAH/PDGFRB/RPL6/SNAP23/MYH9/FLNC/TEK/NEDD9/FAP/SORBS1/THY1/MCAM/LIMS1/NCKAP1/ITGB8/CSRP2/NOX4/FAM107A/USP33/FLNA/ARPC2/DDR2/CAV1/ITGBL1/CSPG4/RPS7/CLASP1/DLC1/GIT2/ITGA2/CSRP1/PCBP2/PFN1/HSPA5/TNC/DCTN4/PTPRC/PARVA/RPL9/HSPA9/ZFYVE21/CD151	105
CC	GO:0044420	extracellular matrix component	23/2573	51/19717	2.04e-08	3.023e-06	2.525e-06	LTBP1/LAMC1/LAMC2/FBN2/ELN/COL27A1/COL4A1/COL4A2/COL14A1/MFAP2/COL5A1/LAMB1/MFAP1/COL12A1/FBLN1/MFAP5/ACAN/NTN4/FBN1/MFAP4/TNC/COL5A2/COL1A2	23
CC	GO:0005604	basement membrane	33/2573	95/19717	5.284e-08	6.526e-06	5.451e-06	COL9A2/SPARC/DLG1/LAMC1/AGRN/EFEMP2/FN1/LAMC2/COL18A1/MMRN2/THBS4/NPNT/NID2/CCDC80/SMOC2/PTN/COL4A1/LOXL1/COL4A2/TIMP3/COL5A1/SMOC1/MATN2/LAMB1/FBLN1/HMCN1/ACAN/VWA1/NTN4/COL17A1/FBN1/TNC/CD151	33
CC	GO:0031091	platelet alpha granule	30/2573	91/19717	7.635e-07	8.082e-05	6.751e-05	CLU/PROS1/FAM49B/ITGB3/ORM1/OLA1/SYTL4/SPARC/CD9/SNCA/CD109/TGFB2/VEGFC/TGFB1/SELP/VWF/GAS6/STXBP1/FN1/SERPING1/TREML1/MMRN1/F8/IGF1/EGF/F13A1/ACTN1/ISLR/SERPINA3/A2M	30
CC	GO:0005581	collagen trimer	29/2573	87/19717	8.958e-07	8.297e-05	6.931e-05	C1QB/C1QA/COL9A2/C1QC/GLDN/COL6A1/COL10A1/COL16A1/MSR1/SCARA3/COL18A1/LOX/COL27A1/COL4A1/COL4A2/COL14A1/C1QTNF1/COL5A1/CTHRC1/C1QTNF7/COL12A1/COL21A1/COLEC12/DCN/COL6A2/COL17A1/COL5A2/CCBE1/COL1A2	29
CC	GO:0005938	cell cortex	68/2573	308/19717	7.442e-06	0.0006128	0.0005118	CTTN/EPS8/PLA2G4C/EPB42/CLDN5/TMOD1/FRYL/RTKN/MYADM/SLC4A1/TRAK1/PARD3/SNCA/PARD6G/PVALB/RND2/C2CD2L/ANLN/CTTNBP2/FMNL1/AKAP13/RHOF/CLASP2/RAI14/SHROOM4/CALD1/RAPGEF3/LAMC2/ARHGEF7/TRAF6/ASPH/FNBP1L/COTL1/MLPH/EEF1A1/RND3/UTRN/ARHGAP32/RHOJ/PHLDB2/PFN4/FERMT2/RND1/PLEKHH2/MELK/BFSP1/CAPZA1/CIB2/MYH9/EXOC3L2/NEDD9/FLNA/HMCN1/PARD6A/CAV1/HCLS1/CLASP1/DLC1/MYH10/ARC/GPSM1/PFN1/UNC13B/DCTN4/STXBP6/GIPC1/CORO1A/PARD6B	68
CC	GO:0031093	platelet alpha granule lumen	22/2573	67/19717	2.366e-05	0.001701	0.001421	CLU/PROS1/FAM49B/ORM1/OLA1/SPARC/TGFB2/VEGFC/TGFB1/VWF/GAS6/FN1/SERPING1/MMRN1/F8/IGF1/EGF/F13A1/ACTN1/ISLR/SERPINA3/A2M	22
CC	GO:0005614	interstitial matrix	8/2573	12/19717	2.525e-05	0.001701	0.001421	NAV2/KAZALD1/CCDC80/SMOC2/ECM2/VIT/VWA1/TNC	8
CC	GO:0036464	cytoplasmic ribonucleoprotein granule	49/2573	212/19717	3.915e-05	0.002418	0.002019	DDX3Y/RBM4/LSM4/PABPC4/MBNL1/CTSG/PNRC2/CNOT8/NUFIP2/SQSTM1/YTHDF2/SARNP/FXR1/DHX9/DYNC1I1/CDK9/TNRC6B/HELZ/TRIM21/ZFP36/EIF2S1/LARP1/RPL28/DDX19A/DCP2/ZC3H12A/NFKBIZ/PABPC3/G3BP2/POLR2G/VCP/ATXN2L/HNRNPK/YBX1/CPEB1/RPL6/NSUN2/ZFAND1/RBPMS/PABPC4L/CNOT7/GHR/UHMK1/POLR2D/RC3H1/STAU1/BARD1/DDX6/CNOT1	49
CC	GO:0001527	microfibril	7/2573	10/19717	5.346e-05	0.00277	0.002314	LTBP1/FBN2/MFAP2/MFAP1/MFAP5/FBN1/MFAP4	7
CC	GO:0031983	vesicle lumen	70/2573	339/19717	5.604e-05	0.00277	0.002314	CLU/HBB/PROS1/FAM49B/SLPI/CHI3L1/PSMD14/CHIT1/PSMD12/ORM1/OLA1/MMP8/XRCC6/SCGB3A2/CTSG/SPARC/LGALS3BP/ARG1/OLFM4/AGA/HSP90B1/PGLYRP1/FABP5/LTF/GHRL/TGFB2/VAT1/VEGFC/TGFB1/PSMD7/ELANE/ACTR10/LCN2/HYOU1/VWF/GAS6/CRISP3/HSP90AA1/FN1/ARHGAP9/CAMP/SERPING1/JUP/EGFR/ECM1/RARRES2/MMRN1/F8/C6orf120/RNASE3/IGF1/COTL1/EEF1A1/EGF/VCP/HP/F13A1/TIMP3/ACTN1/CCT8/PSMB7/ISLR/SERPINA3/PSMD1/PYGB/CXCL1/HSP90AB1/A2M/PRSS2/CLEC3B	70
CC	GO:0005788	endoplasmic reticulum lumen	65/2573	309/19717	5.695e-05	0.00277	0.002314	CLU/COL9A2/LTBP1/TOR3A/MBTPS1/COL6A1/PROC/CSF1/SDF2L1/HSP90B1/GHRL/LAMC1/WNT5B/FSTL1/PDIA3/HYOU1/GAS6/ERP29/COL10A1/FKBP10/FN1/COL16A1/CERCAM/SDC2/DNAJC10/COL18A1/SPP1/SERPINH1/F8/COL27A1/COL4A1/COL4A2/IGFBP4/IGFBP5/IL12A/COL14A1/MXRA8/TSPAN14/SPARCL1/COL5A1/GPX8/CP/CNPY3/LAMB1/COL12A1/COL21A1/WNT5A/VWA1/PRKCSH/COL6A2/STC2/COL17A1/ITIH2/ARSJ/FBN1/TMEM43/WFS1/SPON1/HSPA5/TNC/COL5A2/CHRDL1/IGFBP3/TXNDC16/COL1A2	65
CC	GO:0010494	cytoplasmic stress granule	21/2573	66/19717	6.087e-05	0.00277	0.002314	RBM4/PABPC4/MBNL1/CTSG/NUFIP2/ZFP36/EIF2S1/LARP1/DDX19A/PABPC3/G3BP2/VCP/ATXN2L/HNRNPK/YBX1/ZFAND1/RBPMS/PABPC4L/RC3H1/STAU1/DDX6	21
CC	GO:0030027	lamellipodium	45/2573	193/19717	6.355e-05	0.00277	0.002314	ITGB3/ABLIM3/CTTN/CD177/PTPRO/STX2/WASF3/PTPN13/APC/WASF2/RAB13/SSH1/CDC42BPA/ACTG2/PLEK2/PHACTR4/RAPH1/RAPGEF3/ARHGEF7/FGD5/PDPN/PLEKHG5/FERMT2/DPYSL3/PLEKHH2/WASF1/FAT1/BCAR1/ENAH/STX4/NEDD9/FAP/NCKAP1/PKN2/FGD3/PODXL/ARPC2/PDLIM4/DGKZ/CSPG4/MYH10/ACTA2/CORO1A/DOCK8/PARVA	45
CC	GO:0031252	cell leading edge	80/2573	403/19717	7.169e-05	0.002951	0.002465	ITGB3/ABLIM3/SPRY2/CTTN/EPS8/BMX/AIF1L/AMPH/SLC9A3R1/KCNC4/CD177/PTPRO/MYADM/ARF1/STX2/WASF3/PTPN13/APC/WASF2/RAB13/DDN/SSH1/CDC42BPA/TPM1/LDB1/ACTG2/PLEK2/PHACTR4/PSD3/PACSIN1/CLASP2/ASAP3/RAPH1/DIAPH1/RAPGEF3/ARHGEF7/FGD5/SPRY4/MTSS1/PDPN/PLEKHG5/EEF1A1/MTMR14/PHLDB2/ANK1/SGCE/FERMT2/DPYSL3/PLEKHH2/ACTN1/WASF1/FAT1/BCAR1/IFIT5/ENAH/MYO1C/MTM1/MYH9/STX4/NEDD9/FAP/THY1/SHISA8/NCKAP1/PKN2/FGD3/FAM107A/PARD6A/PODXL/ARPC2/PDLIM4/DGKZ/CSPG4/DLC1/MYH10/ACTA2/CORO1A/DOCK8/PARVA/EPS8L1	80
CC	GO:0060205	cytoplasmic vesicle lumen	69/2573	338/19717	9.111e-05	0.003553	0.002968	CLU/HBB/PROS1/FAM49B/SLPI/CHI3L1/PSMD14/CHIT1/PSMD12/ORM1/OLA1/MMP8/XRCC6/SCGB3A2/CTSG/SPARC/LGALS3BP/ARG1/OLFM4/AGA/HSP90B1/PGLYRP1/FABP5/LTF/GHRL/TGFB2/VAT1/VEGFC/TGFB1/PSMD7/ELANE/ACTR10/LCN2/HYOU1/VWF/GAS6/CRISP3/HSP90AA1/FN1/ARHGAP9/CAMP/SERPING1/JUP/ECM1/RARRES2/MMRN1/F8/C6orf120/RNASE3/IGF1/COTL1/EEF1A1/EGF/VCP/HP/F13A1/TIMP3/ACTN1/CCT8/PSMB7/ISLR/SERPINA3/PSMD1/PYGB/CXCL1/HSP90AB1/A2M/PRSS2/CLEC3B	69
CC	GO:0035770	ribonucleoprotein granule	49/2573	223/19717	0.0001492	0.005526	0.004616	DDX3Y/RBM4/LSM4/PABPC4/MBNL1/CTSG/PNRC2/CNOT8/NUFIP2/SQSTM1/YTHDF2/SARNP/FXR1/DHX9/DYNC1I1/CDK9/TNRC6B/HELZ/TRIM21/ZFP36/EIF2S1/LARP1/RPL28/DDX19A/DCP2/ZC3H12A/NFKBIZ/PABPC3/G3BP2/POLR2G/VCP/ATXN2L/HNRNPK/YBX1/CPEB1/RPL6/NSUN2/ZFAND1/RBPMS/PABPC4L/CNOT7/GHR/UHMK1/POLR2D/RC3H1/STAU1/BARD1/DDX6/CNOT1	49
CC	GO:0034774	secretory granule lumen	65/2573	321/19717	0.0001826	0.006443	0.005382	CLU/PROS1/FAM49B/SLPI/CHI3L1/PSMD14/CHIT1/PSMD12/ORM1/OLA1/MMP8/XRCC6/CTSG/SPARC/LGALS3BP/ARG1/OLFM4/AGA/PGLYRP1/FABP5/LTF/GHRL/TGFB2/VAT1/VEGFC/TGFB1/PSMD7/ELANE/ACTR10/LCN2/VWF/GAS6/CRISP3/HSP90AA1/FN1/ARHGAP9/CAMP/SERPING1/JUP/ECM1/RARRES2/MMRN1/F8/C6orf120/RNASE3/IGF1/COTL1/EEF1A1/EGF/VCP/HP/F13A1/TIMP3/ACTN1/CCT8/PSMB7/ISLR/SERPINA3/PSMD1/PYGB/CXCL1/HSP90AB1/A2M/PRSS2/CLEC3B	65
CC	GO:0016607	nuclear speck	77/2573	397/19717	0.0002089	0.007037	0.005878	RBM14/LPXN/ARHGAP18/BCLAF1/RBM4/SRRM1/BRD2/AAGAB/PHF5A/SF3B2/CCNL1/BDNF/WTAP/SYF2/NXT1/AKAP8L/SRRM2/SMC5/YTHDC1/DUSP10/SARNP/DDX42/SFPQ/CBX4/SFMBT2/THOC2/ZC3H13/CYGB/HIPK1/IFI16/RSRC1/HBP1/U2AF1L4/CWC25/HSF4/RAF1/NFKBIZ/NFATC4/PQBP1/GCAT/ATPAF2/U2AF1/FAM76B/ATXN2L/PABPN1/WAC/CSNK1A1/PLCB1/NOSTRIN/RCHY1/SETD1B/NXF1/CLK3/GLIS2/MEOX2/FNDC1/GLI3/NR3C1/SF3B1/EP400/RREB1/FAM107A/ELL/NONO/NR4A2/CNOT7/CHD5/DGKZ/SMNDC1/CDC5L/POLR2D/BARD1/SRP54/CDK13/DDX46/PIN1/ZNF830	77
CC	GO:0008305	integrin complex	12/2573	31/19717	0.0003028	0.009133	0.007629	ITGB3/ITGB5/ITGA4/ITGA7/NPNT/ITGA9/ITGA3/ITGAL/ITGB8/ITGBL1/LYN/ITGA2	12
CC	GO:0005911	cell-cell junction	86/2573	459/19717	0.000307	0.009133	0.007629	SIRT2/SCN1B/IQGAP3/FGF13/CLDN5/CCDC85C/MPP5/MYADM/APC/WASF2/PARD3/RAB13/PARD6G/SMAD7/LIMS2/CDCA3/DLG1/ESAM/FRMD4A/CDC42BPA/TRAF4/PLEKHA7/SHROOM4/CCND1/GJA5/FLCN/GJA4/CLDN11/JUP/VAV1/JAM2/P2RX7/OBSL1/LDB3/PLEKHG5/FLRT2/CDH26/PAK4/NPHP1/GJB6/CEACAM1/KCNA5/STEAP1/MXRA8/AHNAK/ACTN1/PKP4/FAT1/FXYD1/FRS2/AMOTL2/PDZD11/SNAP23/MYH9/TEK/SORBS1/MPP7/CADM3/FZD5/ANK2/MPDZ/LIMS1/OXTR/PKN2/FLNA/TJP1/HMCN1/MAGI2/PARD6A/PODXL/PDLIM4/CDH5/TMEM47/COL17A1/LYN/IGSF21/TNKS1BP1/FZD4/CGNL1/STXBP6/CDH6/CORO1A/CLDN10/PARD6B/CDH11/DDX6	86
CC	GO:0042581	specific granule	37/2573	160/19717	0.0003237	0.009133	0.007629	SLC15A4/ANXA3/SLPI/CHI3L1/CHIT1/ORM1/SLC2A5/MMP8/STOM/CD177/ARG1/OLFM4/PGLYRP1/RAB37/LTF/CD59/ELANE/LCN2/CRISP3/CAMP/JUP/UBR4/HP/CEACAM8/STK10/CEACAM1/ITGAL/TMC6/TSPAN14/HVCN1/SNAP23/STX4/CXCL1/PGRMC1/SLC44A2/PTPRB/MMP25	37
CC	GO:0005667	transcription factor complex	71/2573	365/19717	0.0003308	0.009133	0.007629	RBM14/TCEA1/JUND/XRCC6/PPARG/YY1/EP300/GATA1/PBX1/TAF4/TAF10/SMAD7/JUN/SFPQ/ARNTL2/NAA16/TAL1/TCF7L1/LDB1/MED8/RXRB/PBX2/CREB1/GTF2H3/HES6/MED7/NFYA/SMAD1/THRB/TRRAP/GTF3C4/FOS/REL/NFATC4/MAX/DDIT3/WWTR1/RELA/MED6/SATB2/SIX1/TAF3/HOXA10/SIX5/NR1D2/TEAD4/KLF4/SOX9/TBX2/KLF5/YAP1/HOXA11/GTF2E1/NONO/NR4A2/RCOR3/HSP90AB1/SSBP3/SIX2/HCLS1/HOXA9/BDP1/TAF1/E2F8/JUNB/NCOA6/NR1H4/SIN3A/NAA15/NR5A2/NFATC3	71
CC	GO:0030139	endocytic vesicle	61/2573	303/19717	0.0003328	0.009133	0.007629	HBB/PLD4/ANXA3/ITGB5/HLA-DPB1/CAMK2G/SCGB3A2/SPARC/RAB13/RAB11FIP4/HSP90B1/CD9/PGLYRP1/LTF/WNT5B/STX8/PDIA3/ELANE/HYOU1/RAB11FIP1/FMNL1/LMBRD1/UBA52/STXBP1/ATP6V0A2/HSP90AA1/MSR1/EGFR/GRIA3/NOS3/AP2A2/MTSS1/PLEKHG5/HP/HLA-B/NOSTRIN/SMO/RAB7B/HVCN1/MYO1C/SNAP23/RAB12/STX4/FZD5/UBC/UVRAG/COLEC12/WNT5A/TLR9/VPS26B/FCHO1/CAV1/HEATR5B/INPP5F/FZD4/RAB8A/UNC13B/GIPC1/CORO1A/HLA-A/SYT11	61
CC	GO:0016324	apical plasma membrane	63/2573	318/19717	0.0004214	0.01115	0.009315	MUC1/DSTYK/SLC2A5/SLC9A3R1/PTPRO/ATP6V1E1/PARD3/CD9/PARD6G/DLG1/ATP1B2/IGFBP2/CYP4F2/C2CD2L/CACNB3/SLC10A2/PTPRH/SHROOM4/FN1/GPR143/EGFR/STC1/CEACAM6/PDPN/MSN/CA4/GPIHBP1/PTH1R/SLC1A1/GJB6/CEACAM1/KCNA5/SLC26A6/OSMR/SLC7A9/KCNMA1/AQP1/FAT1/FXYD1/AMOTL2/EMP2/PDGFRB/CD34/NOTCH1/KCNA1/TEK/THY1/ANK2/MPDZ/SLC23A1/OXTR/NOX4/TLR9/PARD6A/PODXL/DDR2/HSP90AB1/CSPG4/ENPEP/KL/KCNK1/PARD6B/CD300LG	63
CC	GO:0071682	endocytic vesicle lumen	9/2573	20/19717	0.0004675	0.01194	0.009977	HBB/SCGB3A2/SPARC/HSP90B1/PGLYRP1/LTF/HYOU1/HSP90AA1/HP	9
CC	GO:0045178	basal part of cell	16/2573	51/19717	0.0005322	0.01315	0.01098	CLASP2/SHROOM4/P2RY12/EGFR/ITGA9/OSCP1/CEACAM1/PHLDB2/AQP1/MYO1C/CD34/TEK/FAP/SLC23A1/CLASP1/ITGA2	16
CC	GO:0044215	other organism	21/2573	77/19717	0.000657	0.01466	0.01225	LTF/NUP93/UBA52/VPS37A/NUP50/KPNA1/NUP153/NUP210/KPNA3/VPS37B/RAE1/NUP188/NUP160/NUP54/IFIT1/NUP214/AQP1/NUP155/UBC/CNOT7/AXL	21
CC	GO:0044216	other organism cell	21/2573	77/19717	0.000657	0.01466	0.01225	LTF/NUP93/UBA52/VPS37A/NUP50/KPNA1/NUP153/NUP210/KPNA3/VPS37B/RAE1/NUP188/NUP160/NUP54/IFIT1/NUP214/AQP1/NUP155/UBC/CNOT7/AXL	21
CC	GO:0044217	other organism part	21/2573	77/19717	0.000657	0.01466	0.01225	LTF/NUP93/UBA52/VPS37A/NUP50/KPNA1/NUP153/NUP210/KPNA3/VPS37B/RAE1/NUP188/NUP160/NUP54/IFIT1/NUP214/AQP1/NUP155/UBC/CNOT7/AXL	21
CC	GO:0001725	stress fiber	19/2573	67/19717	0.0006925	0.01466	0.01225	ABLIM3/MYL9/TRIP6/FBLIM1/TPM1/SHROOM4/LDB3/FERMT2/ACTN1/MYH9/TEK/SORBS1/NOX4/FAM107A/ROR1/PDLIM4/MYH10/DCTN4/LIMCH1	19
CC	GO:0097517	contractile actin filament bundle	19/2573	67/19717	0.0006925	0.01466	0.01225	ABLIM3/MYL9/TRIP6/FBLIM1/TPM1/SHROOM4/LDB3/FERMT2/ACTN1/MYH9/TEK/SORBS1/NOX4/FAM107A/ROR1/PDLIM4/MYH10/DCTN4/LIMCH1	19
CC	GO:0098636	protein complex involved in cell adhesion	12/2573	34/19717	0.0008078	0.0158	0.0132	ITGB3/ITGB5/ITGA4/ITGA7/NPNT/ITGA9/ITGA3/ITGAL/ITGB8/ITGBL1/LYN/ITGA2	12
CC	GO:0018995	host	20/2573	73/19717	0.0008209	0.0158	0.0132	NUP93/UBA52/VPS37A/NUP50/KPNA1/NUP153/NUP210/KPNA3/VPS37B/RAE1/NUP188/NUP160/NUP54/IFIT1/NUP214/AQP1/NUP155/UBC/CNOT7/AXL	20
CC	GO:0043657	host cell	20/2573	73/19717	0.0008209	0.0158	0.0132	NUP93/UBA52/VPS37A/NUP50/KPNA1/NUP153/NUP210/KPNA3/VPS37B/RAE1/NUP188/NUP160/NUP54/IFIT1/NUP214/AQP1/NUP155/UBC/CNOT7/AXL	20
CC	GO:0031253	cell projection membrane	66/2573	345/19717	0.0008318	0.0158	0.0132	ITGB3/SPRY2/EPS8/BMX/AIF1L/SLC9A3R1/GUCY2D/KCNC4/APC/EVC/DLG1/DDN/TPM1/PLEK2/PSD3/PACSIN1/CLASP2/PTPRH/EVC2/DIAPH1/P2RY12/ABCA4/FGD5/MCHR1/SPRY4/PDPN/ITGA3/MSN/CA4/EEF1A1/PTH1R/UTRN/BBS1/CEACAM1/ROM1/ANK1/SLC26A6/SGCE/FERMT2/SLC7A9/SYTL1/MXRA8/SMO/AQP1/IFIT5/GAP43/MYO1C/FAP/THY1/SHISA8/NCKAP1/FAM107A/PODXL/ARPC2/HSP90AB1/CSPG4/TMEM17/DLC1/TMEM231/PDE6G/DMD/TMEM67/KCNK1/DOCK8/SHANK3/EPS8L1	66
CC	GO:0045177	apical part of cell	72/2573	384/19717	0.0008891	0.01647	0.01376	MUC1/DSTYK/ACVR1/SLC2A5/SLC9A3R1/PTPRO/ATP6V1E1/PARD3/CD9/PARD6G/DLG1/ATP1B2/IGFBP2/CYP4F2/C2CD2L/CACNB3/SLC10A2/PTPRH/SHROOM4/FN1/GPR143/EGFR/STC1/CEACAM6/PDPN/MSN/CA4/VASH1/GPIHBP1/SLC25A27/PTH1R/SLC1A1/GJB6/CEACAM1/NIN/KCNA5/SLC26A6/OSMR/SLC7A9/PLAT/KCNMA1/AQP1/FAT1/FXYD1/IFIT5/AMOTL2/EMP2/PDGFRB/CD34/NOTCH1/KCNA1/TEK/FAP/THY1/ANK2/MPDZ/SLC23A1/OXTR/NOX4/TLR9/TJP1/BYSL/PARD6A/PODXL/DDR2/HSP90AB1/CSPG4/ENPEP/KL/KCNK1/PARD6B/CD300LG	72
CC	GO:0005913	cell-cell adherens junction	28/2573	117/19717	0.0009322	0.01685	0.01407	MPP5/APC/PARD3/SMAD7/CDCA3/PLEKHA7/JUP/LDB3/CDH26/PAK4/ACTN1/PKP4/FRS2/SNAP23/MYH9/SORBS1/OXTR/TJP1/HMCN1/PDLIM4/CDH5/LYN/IGSF21/TNKS1BP1/STXBP6/CDH6/CDH11/DDX6	28
CC	GO:0032432	actin filament bundle	20/2573	75/19717	0.001186	0.02092	0.01748	ABLIM3/MYL9/TRIP6/FBLIM1/TPM1/SHROOM4/LDB3/FERMT2/ACTN1/MYH9/TEK/SORBS1/NOX4/FAM107A/ROR1/PDLIM4/MYH10/DCTN4/CRYAB/LIMCH1	20
CC	GO:0001726	ruffle	37/2573	172/19717	0.001362	0.02347	0.0196	ITGB3/SPRY2/CTTN/EPS8/BMX/AIF1L/SLC9A3R1/MYADM/APC/WASF2/TPM1/PSD3/PACSIN1/CLASP2/ASAP3/DIAPH1/ARHGEF7/FGD5/SPRY4/MTSS1/PDPN/EEF1A1/MTMR14/ACTN1/BCAR1/IFIT5/MYO1C/MTM1/MYH9/FAP/NCKAP1/FGD3/FAM107A/PARD6A/PODXL/DLC1/EPS8L1	37
CC	GO:0043296	apical junction complex	32/2573	143/19717	0.001417	0.02386	0.01993	CLDN5/CCDC85C/MPP5/APC/PARD3/RAB13/PARD6G/DLG1/ESAM/FRMD4A/TRAF4/PLEKHA7/SHROOM4/CCND1/CLDN11/JUP/JAM2/NPHP1/MXRA8/AMOTL2/SORBS1/MPP7/FZD5/MPDZ/PKN2/TJP1/MAGI2/PARD6A/CDH5/CGNL1/CLDN10/PARD6B	32
CC	GO:0001650	fibrillar center	30/2573	132/19717	0.001518	0.025	0.02089	SELENBP1/HOXB5/KLF6/SPATA2/LIPA/KDM5D/SMAD7/FBLIM1/NFKBIE/RAI14/CHD1/NOLC1/MAP3K14/NFIB/DAB2/DCLRE1A/DDX11/ARHGAP32/RAE1/CRIPT/RPAIN/NUFIP1/RREB1/RNMT/APEX2/TCOF1/RSAD2/FOXJ2/DDX46/THAP1	30
CC	GO:0098978	glutamatergic synapse	65/2573	349/19717	0.001822	0.02934	0.02451	ITGB3/ABLIM3/NRCAM/EPS8/GRIP1/PTPRO/SPARC/ARF1/WASF3/CPT1C/DLG1/GHRL/FXR1/PHB2/CTTNBP2/NRP1/STXBP1/DLG2/GRIP2/GPC4/KPNA1/RELA/YWHAZ/CADPS2/VCP/PLCB1/GPC6/PRR7/GRASP/PLAT/EFNB2/RNF216/ACTN1/DNM1/SPARCL1/PCDH17/KCNA1/STX4/PPP3CB/WNT5A/PAK3/FLNA/ACAN/ARPC2/DGKZ/NLGN4X/MTOR/LYN/RGS14/MYH10/DYNLL2/FZD4/ARC/RAB8A/PFN1/UNC13B/PRKAR2B/STAU1/EPHB2/GIPC1/CORO1A/CDH11/PIN1/OLFM2/KCNA3	65
CC	GO:0005643	nuclear pore	22/2573	89/19717	0.002025	0.03193	0.02667	EIF5A/NXT1/NUP93/IPO7/DDX19A/NUP50/KPNA1/NUP153/NUP210/KPNA3/RAE1/NUP188/NUP160/NUP54/NXF1/NUP214/NUP155/MYO1C/MCM3AP/NUP210L/RANGAP1/IPO5	22
CC	GO:0017053	transcriptional repressor complex	21/2573	84/19717	0.002182	0.0334	0.0279	SIRT2/SPEN/GATA1/LIN37/JUN/ELANE/LIN9/ARID4A/CCND1/ZBTB7A/SIRT1/SP3/DEPDC1/MTA1/RLIM/GLI3/TBX15/REST/RCOR3/CHD5/SIN3A	21
CC	GO:0022626	cytosolic ribosome	26/2573	112/19717	0.002209	0.0334	0.0279	RPS27/RPS28/RPS27L/EIF2AK4/RPS15/UBA52/RPS26/RPLP1/RPL28/RPS3A/RPL10/EIF2A/RPL29/RSL24D1/RPS8/RPS4Y1/RPS2/RPL39/RPS10/RPL6/NUFIP1/RPL14/RPS7/RPL22L1/RPL9/RPL15	26
CC	GO:0042641	actomyosin	20/2573	79/19717	0.002342	0.03471	0.02899	ABLIM3/MYL9/TRIP6/FBLIM1/CDC42BPA/TPM1/SHROOM4/LDB3/FERMT2/ACTN1/MYH9/TEK/SORBS1/NOX4/FAM107A/ROR1/PDLIM4/MYH10/DCTN4/LIMCH1	20
CC	GO:0042383	sarcolemma	30/2573	136/19717	0.002473	0.03593	0.03001	SRI/SCN1B/SLC2A5/COL6A1/RTN2/CAV2/DLG1/CACNB3/FKRP/SGCD/KCND3/STAC/STAC2/UTRN/BGN/ANK1/SGCE/AHNAK/SSPN/AQP1/FXYD1/CIB2/FLNC/PPP3CB/ANK2/SGCB/RYR2/CAV1/COL6A2/DMD	30
CC	GO:0005775	vacuolar lumen	36/2573	172/19717	0.002572	0.03664	0.03061	IDS/CTSG/ARG1/LIPA/AGA/FABP5/VAT1/AGRN/ELANE/ACTR10/HSP90AA1/SDC2/GPC4/NAAA/C6orf120/RNASE3/DAPK2/VCP/EPDR1/GPC6/BGN/CCT8/PDGFRB/SERPINA3/PSMD1/GPC1/PYGB/DCN/CTSF/ACAN/OGN/CSPG4/FMOD/PRELP/PRSS2/HYAL1	36
CC	GO:0005796	Golgi lumen	24/2573	102/19717	0.002648	0.03703	0.03093	PROS1/MUC1/PROC/WNT5B/TGFB1/AGRN/GAS6/PCSK6/SDC2/GPC4/GPC6/BGN/MUC2/GPC1/WNT5A/DCN/ACAN/OGN/CSPG4/SOD3/MUC3A/FMOD/PRELP/DEFB1	24
CC	GO:0009925	basal plasma membrane	11/2573	34/19717	0.002936	0.04029	0.03365	SHROOM4/P2RY12/EGFR/ITGA9/OSCP1/CEACAM1/AQP1/MYO1C/CD34/TEK/SLC23A1	11
CC	GO:0022627	cytosolic small ribosomal subunit	13/2573	44/19717	0.003143	0.04235	0.03537	RPS27/RPS28/RPS27L/RPS15/UBA52/RPS26/RPS3A/EIF2A/RPS8/RPS4Y1/RPS2/RPS10/RPS7	13
CC	GO:0030863	cortical cytoskeleton	26/2573	116/19717	0.003685	0.04877	0.04073	CTTN/EPB42/CLDN5/TMOD1/RTKN/MYADM/SLC4A1/PVALB/ANLN/AKAP13/SHROOM4/CALD1/RAPGEF3/COTL1/MLPH/EEF1A1/UTRN/PLEKHH2/CAPZA1/CIB2/MYH9/FLNA/HCLS1/CLASP1/DLC1/CORO1A	26
CC	GO:0031092	platelet alpha granule membrane	7/2573	17/19717	0.003759	0.04887	0.04082	ITGB3/SYTL4/SPARC/CD9/SNCA/CD109/SELP	7
CC	GO:0005923	bicellular tight junction	27/2573	123/19717	0.004237	0.05379	0.04493	CLDN5/CCDC85C/MPP5/APC/PARD3/RAB13/PARD6G/DLG1/ESAM/FRMD4A/TRAF4/CCND1/CLDN11/JAM2/NPHP1/MXRA8/AMOTL2/MPP7/FZD5/MPDZ/TJP1/MAGI2/PARD6A/CDH5/CGNL1/CLDN10/PARD6B	27
CC	GO:0098858	actin-based cell projection	41/2573	208/19717	0.004283	0.05379	0.04493	ITGB3/EPS8/FGF13/SLC9A3R1/TBC1D10A/ATP6V1E1/NGDN/TGFB1/PVALB/ACTG2/SLC10A2/PTPRH/RAPH1/RAPGEF3/LOXHD1/AOC3/ADCY6/PDPN/ITGA3/MSN/UTRN/PDGFRA/CEACAM1/MAP2/SYTL1/FAT1/FARP1/ENAH/GAP43/MYO1C/MTM1/CIB2/TEK/FCHSD2/OXTR/PODXL/DNALI1/SPN/DMD/ACTA2/MYO15A	41
CC	GO:0044449	contractile fiber part	43/2573	221/19717	0.004477	0.05484	0.04581	SRI/MYL9/FHL2/TMOD1/SLC4A1/ARF1/MYL6B/SQSTM1/MYL4/FXR1/TPM1/NEXN/LRRC39/PDE4B/JUP/HSPB1/NPNT/OBSL1/LDB3/KCNA5/ANK1/FERMT2/LMOD1/AHNAK/ACTN1/MTM1/FLNC/FKBP1B/TIMP4/MTMR12/PPP3CB/ANK2/CSRP2/FLNA/RYR2/PDLIM4/DMD/CSRP1/ACTA2/CMYA5/DCTN4/CRYAB/PARVA	43
CC	GO:0044391	ribosomal subunit	38/2573	190/19717	0.004515	0.05484	0.04581	RPS27/RPS28/MRPL36/RPS27L/RPS15/MRPL44/MRPL48/UBA52/RPS26/RBM3/RPLP1/RPL28/RPS3A/MRPL15/MRPL20/RPL10/EIF2A/MRPS28/RPL29/RSL24D1/MRPS14/RPS8/RPS4Y1/RPS2/RPL39/RPS10/MRPL18/RPL6/MRPL13/MRPL21/MRPL17/RPL14/RPS7/MRPL54/RPL22L1/RPL9/MRPL2/RPL15	38
CC	GO:0043292	contractile fiber	45/2573	234/19717	0.00464	0.05546	0.04633	SRI/MYL9/FHL2/TMOD1/SLC4A1/ARF1/MYL6B/SQSTM1/MYL4/FXR1/TPM1/NEXN/LRRC39/CALD1/PDE4B/JUP/HSPB1/NPNT/OBSL1/LDB3/KCNA5/ANK1/FERMT2/LMOD1/AHNAK/ACTN1/MTM1/FLNC/FKBP1B/TIMP4/MTMR12/PPP3CB/CDK5R1/ANK2/CSRP2/FLNA/RYR2/PDLIM4/DMD/CSRP1/ACTA2/CMYA5/DCTN4/CRYAB/PARVA	45
CC	GO:0031258	lamellipodium membrane	8/2573	22/19717	0.004864	0.05721	0.04779	ITGB3/PLEK2/PDPN/FERMT2/FAP/NCKAP1/CSPG4/DOCK8	8
CC	GO:0035580	specific granule lumen	16/2573	62/19717	0.005019	0.05811	0.04854	SLPI/CHI3L1/CHIT1/ORM1/MMP8/ARG1/OLFM4/PGLYRP1/LTF/ELANE/LCN2/CRISP3/CAMP/JUP/HP/CXCL1	16
CC	GO:0030864	cortical actin cytoskeleton	21/2573	90/19717	0.005246	0.05981	0.04996	CTTN/CLDN5/RTKN/MYADM/PVALB/ANLN/AKAP13/SHROOM4/CALD1/RAPGEF3/COTL1/MLPH/EEF1A1/UTRN/PLEKHH2/CAPZA1/CIB2/MYH9/HCLS1/DLC1/CORO1A	21
CC	GO:0031010	ISWI-type complex	5/2573	10/19717	0.005373	0.06033	0.05039	CHRAC1/RSF1/BPTF/SMARCA1/C17orf49	5
CC	GO:0038201	TOR complex	6/2573	14/19717	0.005779	0.06391	0.05338	LARP1/TELO2/SESN2/SESN3/MTOR/MAPKAP1	6
CC	GO:0031528	microvillus membrane	8/2573	23/19717	0.006617	0.07211	0.06023	ITGB3/SLC9A3R1/PTPRH/PDPN/MSN/CEACAM1/SYTL1/PODXL	8
CC	GO:0070160	tight junction	27/2573	128/19717	0.007408	0.07956	0.06645	CLDN5/CCDC85C/MPP5/APC/PARD3/RAB13/PARD6G/DLG1/ESAM/FRMD4A/TRAF4/CCND1/CLDN11/JAM2/NPHP1/MXRA8/AMOTL2/MPP7/FZD5/MPDZ/TJP1/MAGI2/PARD6A/CDH5/CGNL1/CLDN10/PARD6B	27
CC	GO:0016605	PML body	22/2573	99/19717	0.007957	0.08301	0.06933	MKNK2/RNF6/AKAP8L/SQSTM1/SMC5/TDG/CDK9/KLHL20/HIPK1/USP7/SIRT1/MAX/SP3/TDP2/PML/RDM1/RPAIN/CHFR/MTOR/RGS14/SPN/THAP1	22
CC	GO:0072562	blood microparticle	30/2573	147/19717	0.008058	0.08301	0.06933	CLU/HBB/PROS1/C1QB/HBD/C1QC/ORM1/STOM/CFH/SLC4A1/LGALS3BP/TGFB1/ACTG2/CFB/FN1/ANGPTL4/SERPING1/EIF2A/MSN/YWHAZ/HP/F13A1/C1R/CP/SERPINA3/CIB2/ITIH2/C1S/A2M/PFN1	30
CC	GO:0005741	mitochondrial outer membrane	35/2573	178/19717	0.008159	0.08301	0.06933	IFI27/PMAIP1/BRI3BP/VPS13C/PPP1R15A/TOMM20/ARG1/MFF/MLXIP/SNCA/CPT1C/RTN4IP1/VAT1/PINK1/PHB2/RAB11FIP5/MOAP1/PDE2A/ABCB6/UBA52/MAOA/RAF1/BCL2L1/ASS1/SNN/BMF/FUNDC1/WASF1/MCL1/SPATA18/ARMCX3/UBC/MTOR/BAK1/RSAD2	35
CC	GO:0005884	actin filament	24/2573	111/19717	0.008177	0.08301	0.06933	CTTN/AIF1L/ARHGAP6/TMOD1/KEAP1/SMTNL2/TPM1/AKAP13/SHROOM4/LDB3/COTL1/DPYSL3/LMOD1/ACTN1/MYO1C/RCSD1/TEK/SMTN/NCKAP1/FLNA/GNG12/PDLIM4/HCLS1/CORO1A	24
CC	GO:0031838	haptoglobin-hemoglobin complex	5/2573	11/19717	0.008801	0.08481	0.07084	HBB/HBD/HBM/HP/HBQ1	5
CC	GO:0031932	TORC2 complex	5/2573	11/19717	0.008801	0.08481	0.07084	TELO2/SESN2/SESN3/MTOR/MAPKAP1	5
CC	GO:0034663	endoplasmic reticulum chaperone complex	5/2573	11/19717	0.008801	0.08481	0.07084	SDF2L1/HSP90B1/HYOU1/DNAJC10/HSPA5	5
CC	GO:0032587	ruffle membrane	21/2573	94/19717	0.008813	0.08481	0.07084	ITGB3/SPRY2/EPS8/BMX/AIF1L/APC/TPM1/PSD3/PACSIN1/CLASP2/DIAPH1/FGD5/SPRY4/PDPN/EEF1A1/IFIT5/MYO1C/FAP/FAM107A/DLC1/EPS8L1	21
CC	GO:0030496	midbody	34/2573	173/19717	0.009092	0.08637	0.07214	SIRT2/TXNDC9/CIT/KEAP1/YPEL5/TACC1/RAB11FIP4/HSP90B1/SSH1/ANLN/FLCN/CRMP1/CHMP1B/DDX11/KIF4A/CYLD/VPS37B/PKP4/PLK1/KIF20A/UVRAG/PKN2/MYH10/RAB8A/HSPA5/CCDC124/HEPACAM2/KATNA1/KIF14/NEK2/LZTS2/PIN1/RNF8/GDI1	34
CC	GO:0005902	microvillus	19/2573	83/19717	0.009484	0.08864	0.07404	ITGB3/SLC9A3R1/TBC1D10A/ATP6V1E1/TGFB1/SLC10A2/PTPRH/RAPGEF3/AOC3/PDPN/MSN/PDGFRA/CEACAM1/SYTL1/MYO1C/TEK/OXTR/PODXL/SPN	19
CC	GO:0045121	membrane raft	56/2573	315/19717	0.00957	0.08864	0.07404	SLC9A3R1/GRIP1/MME/INPP5D/FAIM2/STOM/EDNRB/CD177/FADD/MYADM/CLIP3/SLC25A5/PRKAR2A/CAV2/TNF/DLG1/BCL10/PPP2CA/RTN4RL1/MALL/P2RY12/PLVAP/BTK/EHD2/EGFR/NOS3/SERPINH1/ERLIN2/CD48/PDPN/TFPI/CBL/KCNA5/SULF1/AHNAK/SMO/KCNMA1/FXYD1/EMP2/HAS2/MYO1C/TEK/SORBS1/THY1/GPC1/ANK2/PODXL/CAV1/LYN/DLC1/KDR/DMD/ARC/PRKAR2B/PTPRC/KCNA3	56
CC	GO:0031248	protein acetyltransferase complex	21/2573	95/19717	0.009958	0.08909	0.07442	PHF20/POLE3/MSL2/EP300/TAF4/TAF10/NAA16/YEATS2/ING3/NAA30/WDR5/CREBBP/TRRAP/RSF1/MORF4L2/HCFC1/NAA25/EP400/EPC1/NAA15/ING5	21
CC	GO:1902493	acetyltransferase complex	21/2573	95/19717	0.009958	0.08909	0.07442	PHF20/POLE3/MSL2/EP300/TAF4/TAF10/NAA16/YEATS2/ING3/NAA30/WDR5/CREBBP/TRRAP/RSF1/MORF4L2/HCFC1/NAA25/EP400/EPC1/NAA15/ING5	21
CC	GO:0005844	polysome	17/2573	72/19717	0.01003	0.08909	0.07442	RPS28/NUFIP2/EIF4B/EIF2AK4/FXR1/DHX9/FUS/EIF2S1/RPS26/LARP1/NAA30/EIF4H/RPS4Y1/RPL39/RPL6/MYH10/LARP6	17
CC	GO:0098857	membrane microdomain	56/2573	316/19717	0.01019	0.08909	0.07442	SLC9A3R1/GRIP1/MME/INPP5D/FAIM2/STOM/EDNRB/CD177/FADD/MYADM/CLIP3/SLC25A5/PRKAR2A/CAV2/TNF/DLG1/BCL10/PPP2CA/RTN4RL1/MALL/P2RY12/PLVAP/BTK/EHD2/EGFR/NOS3/SERPINH1/ERLIN2/CD48/PDPN/TFPI/CBL/KCNA5/SULF1/AHNAK/SMO/KCNMA1/FXYD1/EMP2/HAS2/MYO1C/TEK/SORBS1/THY1/GPC1/ANK2/PODXL/CAV1/LYN/DLC1/KDR/DMD/ARC/PRKAR2B/PTPRC/KCNA3	56
CC	GO:0034708	methyltransferase complex	24/2573	113/19717	0.01022	0.08909	0.07442	PHF20/UTY/WTAP/CLNS1A/TAF4/KDM5D/ZC3H13/KDM6B/ZNF462/WDR5/RIOK1/SIRT1/MAX/SNRPB/SETD1B/HCFC1/JARID2/REST/EZH1/RNMT/TAF1/N6AMT1/NCOA6/C17orf49	24
CC	GO:0045335	phagocytic vesicle	27/2573	132/19717	0.01117	0.09626	0.0804	PLD4/ANXA3/ITGB5/PGLYRP1/LTF/STX8/PDIA3/ELANE/RAB11FIP1/FMNL1/STXBP1/ATP6V0A2/HLA-B/RAB7B/HVCN1/MYO1C/SNAP23/RAB12/STX4/UVRAG/TLR9/VPS26B/RAB8A/UNC13B/CORO1A/HLA-A/SYT11	27
CC	GO:0031256	leading edge membrane	33/2573	170/19717	0.01205	0.1026	0.08572	ITGB3/SPRY2/EPS8/BMX/AIF1L/AMPH/KCNC4/APC/DDN/TPM1/PLEK2/PSD3/PACSIN1/CLASP2/DIAPH1/FGD5/SPRY4/PDPN/EEF1A1/ANK1/SGCE/FERMT2/IFIT5/MYO1C/FAP/THY1/SHISA8/NCKAP1/FAM107A/CSPG4/DLC1/DOCK8/EPS8L1	33
CC	GO:0044445	cytosolic part	45/2573	247/19717	0.01234	0.1039	0.08682	HBB/HBD/RPS27/PSMD14/RPS28/FADD/CASP4/RPS27L/PRKCB/EIF2AK4/FXN/RPS15/AHSP/UBA52/RPS26/RPLP1/RPL28/RPS3A/HBM/RPL10/EIF2A/RPL29/RSL24D1/RPS8/RPS4Y1/UBL4A/RPS2/RPL39/RPS10/CCT8/IDE/IFIT5/RPL6/HBQ1/NUFIP1/PSMD1/NLRP1/RPL14/RPS7/MTOR/RPL22L1/RPL9/RPL15/PIN1/PFKP	45
CC	GO:0031461	cullin-RING ubiquitin ligase complex	31/2573	158/19717	0.0126	0.1049	0.08765	DCAF8/ENC1/SPSB1/FBXO33/DCAF12/PEF1/KEAP1/DEPDC5/DCAF6/KLHL15/KLHL20/TRIM21/ARIH2/FBXO38/FBXW7/FBXW8/FBXO4/UBE2S/BUB1B/ANAPC10/FBXL13/FBXL8/SPSB3/UBE2C/SKP2/FBXO25/FBXL14/ARIH1/TNFAIP1/CUL1/SPSB2	31
CC	GO:0019867	outer membrane	38/2573	203/19717	0.01338	0.1098	0.09172	IFI27/PMAIP1/BRI3BP/VPS13C/GUCY2D/PPP1R15A/TOMM20/NAV3/ARG1/MFF/MLXIP/SNCA/CPT1C/RTN4IP1/VAT1/PINK1/PHB2/RAB11FIP5/MOAP1/PDE2A/ABCB6/UBA52/MAOA/RAF1/BCL2L1/ASS1/SNN/BMF/FUNDC1/WASF1/MCL1/ANKH/SPATA18/ARMCX3/UBC/MTOR/BAK1/RSAD2	38
CC	GO:0005833	hemoglobin complex	5/2573	12/19717	0.01349	0.1098	0.09172	HBB/HBD/AHSP/HBM/HBQ1	5
CC	GO:0044452	nucleolar part	34/2573	178/19717	0.01388	0.1113	0.09299	SELENBP1/HOXB5/WDR37/KLF6/SPATA2/LIPA/KDM5D/SMAD7/FBLIM1/NFKBIE/RAI14/CHD1/NOLC1/MAP3K14/NFIB/DAB2/DCLRE1A/DDX11/ARHGAP32/RAE1/CRIPT/RPAIN/NUFIP1/RREB1/SIRT7/RNMT/APEX2/TCOF1/RSAD2/FOXJ2/DDX46/NHP2/THAP1/CLEC3B	34
CC	GO:0042827	platelet dense granule	7/2573	21/19717	0.01404	0.1113	0.09299	ITPR1/LGALS3BP/SELP/ECM1/RARRES2/TIMP3/CLEC3B	7
CC	GO:0098589	membrane region	57/2573	328/19717	0.01412	0.1113	0.09299	SLC9A3R1/GRIP1/MME/INPP5D/FAIM2/STOM/EDNRB/EIF5A/CD177/FADD/MYADM/CLIP3/SLC25A5/PRKAR2A/CAV2/TNF/DLG1/BCL10/PPP2CA/RTN4RL1/MALL/P2RY12/PLVAP/BTK/EHD2/EGFR/NOS3/SERPINH1/ERLIN2/CD48/PDPN/TFPI/CBL/KCNA5/SULF1/AHNAK/SMO/KCNMA1/FXYD1/EMP2/HAS2/MYO1C/TEK/SORBS1/THY1/GPC1/ANK2/PODXL/CAV1/LYN/DLC1/KDR/DMD/ARC/PRKAR2B/PTPRC/KCNA3	57
CC	GO:0000151	ubiquitin ligase complex	50/2573	282/19717	0.0144	0.1114	0.09306	DCAF8/ENC1/SPSB1/FBXO33/DCAF12/PEF1/KEAP1/MED10/YPEL5/BCOR/DEPDC5/DCAF6/KLHL15/CBX4/KLHL20/TRIM21/ARIH2/RMND5A/FBXO38/MED7/FBXW7/FBXW8/FBXO4/UBE2S/DERL1/UBE4B/BUB1B/RCHY1/ANAPC10/MED30/FBXL13/FBXL8/PHC3/SPSB3/UBE2C/SKP2/UBE2D3/FBXO25/FBXL14/USP33/RNF19B/ARIH1/PCGF2/AUP1/TNFAIP1/BARD1/FBXO8/CUL1/RNF8/SPSB2	50
CC	GO:0030017	sarcomere	38/2573	204/19717	0.01443	0.1114	0.09306	SRI/MYL9/FHL2/TMOD1/SLC4A1/ARF1/SQSTM1/MYL4/TPM1/NEXN/LRRC39/PDE4B/JUP/HSPB1/OBSL1/LDB3/KCNA5/ANK1/FERMT2/LMOD1/ACTN1/MTM1/FLNC/FKBP1B/TIMP4/MTMR12/PPP3CB/ANK2/CSRP2/FLNA/RYR2/PDLIM4/DMD/CSRP1/CMYA5/DCTN4/CRYAB/PARVA	38
CC	GO:0030016	myofibril	41/2573	224/19717	0.01515	0.1158	0.09669	SRI/MYL9/FHL2/TMOD1/SLC4A1/ARF1/SQSTM1/MYL4/FXR1/TPM1/NEXN/LRRC39/CALD1/PDE4B/JUP/HSPB1/OBSL1/LDB3/KCNA5/ANK1/FERMT2/LMOD1/AHNAK/ACTN1/MTM1/FLNC/FKBP1B/TIMP4/MTMR12/PPP3CB/ANK2/CSRP2/FLNA/RYR2/PDLIM4/DMD/CSRP1/CMYA5/DCTN4/CRYAB/PARVA	41
CC	GO:0019005	SCF ubiquitin ligase complex	15/2573	64/19717	0.01605	0.1213	0.1014	SPSB1/FBXO33/TRIM21/FBXO38/FBXW7/FBXO4/FBXL13/FBXL8/SPSB3/SKP2/FBXO25/FBXL14/ARIH1/CUL1/SPSB2	15
CC	GO:0030014	CCR4-NOT complex	6/2573	17/19717	0.01686	0.1262	0.1054	CNOT8/CNOT4/ZFP36/CNOT7/TNKS1BP1/CNOT1	6
CC	GO:0016234	inclusion body	18/2573	82/19717	0.01737	0.1287	0.1075	CLU/EDEM1/SNCA/SQSTM1/STRADB/PINK1/SFMBT2/HERPUD1/NEFH/TDP2/NUP153/PABPN1/NXF1/HOXC9/RANGAP1/ARIH1/HSP90AB1/RNF32	18
CC	GO:0031968	organelle outer membrane	37/2573	201/19717	0.01861	0.1353	0.113	IFI27/PMAIP1/BRI3BP/VPS13C/GUCY2D/PPP1R15A/TOMM20/NAV3/ARG1/MFF/MLXIP/SNCA/CPT1C/RTN4IP1/VAT1/PINK1/PHB2/RAB11FIP5/MOAP1/PDE2A/ABCB6/UBA52/MAOA/RAF1/BCL2L1/ASS1/SNN/BMF/FUNDC1/WASF1/MCL1/SPATA18/ARMCX3/UBC/MTOR/BAK1/RSAD2	37
CC	GO:0005689	U12-type spliceosomal complex	8/2573	27/19717	0.01862	0.1353	0.113	PHF5A/SF3B2/SF3B5/LSM7/SF3B4/SNRPB/YBX1/SF3B1	8
CC	GO:0005819	spindle	59/2573	347/19717	0.01939	0.1387	0.1159	SIRT2/CTTN/RASSF1/POLB/BEX4/KATNAL2/YPEL5/PPP2R3C/RAB11FIP4/SLC25A5/PTP4A1/PPP2CA/UNC119/YEATS2/DYNC1I1/LRMP/CLASP2/DIAPH1/TPX2/CEP350/CRMP1/DDX11/KIF4A/CYLD/HSPB1/HECW2/MTUS1/HAUS8/ACOT13/BUB1B/ODF2/RAE1/NIN/TMEM201/MID1/PKP4/PLK3/PLK1/KIF20A/FAM110A/NSUN2/MYH9/NEDD9/NR3C1/RANGAP1/HAUS2/NDE1/EML1/TTK/KATNAL1/CLASP1/RGS14/MYH10/DCTN4/PIN4/HEPACAM2/KATNA1/KIF14/NEK2	59
CC	GO:0036038	MKS complex	5/2573	13/19717	0.0196	0.1387	0.1159	B9D1/B9D2/TMEM17/TMEM231/TMEM67	5
CC	GO:0043202	lysosomal lumen	20/2573	95/19717	0.01965	0.1387	0.1159	IDS/LIPA/AGRN/HSP90AA1/SDC2/GPC4/NAAA/EPDR1/GPC6/BGN/PDGFRB/GPC1/DCN/CTSF/ACAN/OGN/CSPG4/FMOD/PRELP/HYAL1	20
CC	GO:0000932	P-body	18/2573	84/19717	0.02195	0.1533	0.1281	LSM4/PNRC2/CNOT8/SQSTM1/YTHDF2/TNRC6B/TRIM21/ZFP36/DCP2/ZC3H12A/POLR2G/CPEB1/RBPMS/CNOT7/POLR2D/RC3H1/DDX6/CNOT1	18
CC	GO:1904724	tertiary granule lumen	13/2573	55/19717	0.02244	0.1533	0.1281	HBB/CHIT1/ORM1/MMP8/YPEL5/OLFM4/PGLYRP1/LTF/CRISP3/CAMP/HP/MMP9/CXCL1	13
CC	GO:0031527	filopodium membrane	6/2573	18/19717	0.02255	0.1533	0.1281	ITGB3/PDPN/ITGA3/UTRN/GAP43/DMD	6
CC	GO:0070993	translation preinitiation complex	6/2573	18/19717	0.02255	0.1533	0.1281	EIF3L/EIF2S1/EIF1/EIF3F/EIF3K/EIF3M	6
CC	GO:0015934	large ribosomal subunit	24/2573	121/19717	0.02284	0.1539	0.1285	MRPL36/MRPL44/MRPL48/UBA52/RBM3/RPLP1/RPL28/MRPL15/MRPL20/RPL10/RPL29/RSL24D1/RPL39/MRPL18/RPL6/MRPL13/MRPL21/MRPL17/RPL14/MRPL54/RPL22L1/RPL9/MRPL2/RPL15	24
CC	GO:0044295	axonal growth cone	8/2573	28/19717	0.02317	0.1547	0.1292	TRAK1/PARD3/FKBP4/L1CAM/BOC/HSP90AA1/NIN/HSP90AB1	8
CC	GO:1902911	protein kinase complex	22/2573	109/19717	0.02367	0.1566	0.1308	ACVR1/PRKAR2A/CDK9/GTF2H3/CCND1/ERN1/IGF1R/ZBTB7A/SESN2/SMCR8/ACVR2A/MAP3K5/CCNT2/CNTD2/CCNY/IFIT5/PRKAG2/SORBS1/CDK5R1/UVRAG/PHKA1/CDK13	22
CC	GO:0035579	specific granule membrane	19/2573	91/19717	0.02447	0.1605	0.134	SLC15A4/SLC2A5/STOM/CD177/RAB37/CD59/UBR4/CEACAM8/STK10/CEACAM1/ITGAL/TMC6/TSPAN14/HVCN1/SNAP23/PGRMC1/SLC44A2/PTPRB/MMP25	19
CC	GO:0030667	secretory granule membrane	51/2573	298/19717	0.02515	0.1635	0.1365	SLC15A4/ITGB3/SRI/SLC2A5/CLEC4C/SYTL4/MME/STOM/ITPR1/CD177/SPARC/CD9/SNCA/CAV2/CD109/RAB37/FABP5/CD59/RND2/SELP/LRMP/RHOF/ICA1/DIAPH1/FCGR3B/PAM/CXCR1/AP2A2/CPE/UBR4/CEACAM6/CA4/PIGR/CEACAM8/STK10/CEACAM1/ITGAL/DDOST/TMC6/TSPAN14/TMEM225/HVCN1/SNAP23/CD300A/CAV1/PGRMC1/SLC44A2/PTPRC/PTPRB/MMP25/LPCAT1	51
CC	GO:0030175	filopodium	21/2573	104/19717	0.0265	0.1708	0.1427	ITGB3/FGF13/SLC9A3R1/NGDN/ACTG2/RAPH1/RAPGEF3/PDPN/ITGA3/MSN/UTRN/MAP2/FAT1/FARP1/ENAH/GAP43/MTM1/PODXL/DNALI1/DMD/ACTA2	21
CC	GO:0032153	cell division site	15/2573	68/19717	0.02713	0.1725	0.1441	CIT/RTKN/RAB11FIP4/SSH1/RND2/ANLN/RHOF/RND3/RND1/KIF20A/MYH9/PKN2/HMCN1/NDE1/MYH10	15
CC	GO:0031089	platelet dense granule lumen	5/2573	14/19717	0.02727	0.1725	0.1441	LGALS3BP/ECM1/RARRES2/TIMP3/CLEC3B	5
CC	GO:0016528	sarcoplasm	17/2573	80/19717	0.02747	0.1725	0.1441	SRI/FSD2/CAMK2G/ITPR1/RTN2/HSP90B1/NOL3/SGCD/THBS4/ASPH/ANK1/FLNC/FKBP1B/MTMR12/RYR2/CMYA5/FABP3	17
CC	GO:0005635	nuclear envelope	75/2573	464/19717	0.0284	0.1744	0.1456	IFI27/TRA2B/PHF20/SCRN1/PLA2G4C/TOR3A/GUCY2D/ITPR1/EDNRB/EIF5A/OSBPL6/NAV3/SCAI/WTAP/RNF6/NXT1/SNCA/TMEM170A/HOXA7/NUP93/IPO9/AKIRIN1/RAP1GAP2/SORL1/LRMP/IPO7/ERN1/DDX19A/MATR3/SMAD1/NUP50/DNAJB14/KPNA1/SIRT1/GCH1/EGFR/BCL2L1/P2RX7/NUP153/NUP210/MTA1/PLCB1/KPNA3/RAE1/NUP188/NUP160/SH3BGRL2/TAF3/NUP54/TMEM201/TMC6/FANCL/NXF1/NUP214/AQP1/NUP155/YBX1/MYO1C/MCM3AP/PLCD4/NUP210L/RANGAP1/IPO5/ALG14/CMTM3/BNIP1/PCYT1A/TMEM43/KPNA4/EPC1/ROGDI/SUN2/MRGPRF/PRICKLE2/ABCF1	75
CC	GO:0071011	precatalytic spliceosome	12/2573	51/19717	0.02858	0.1744	0.1456	PHF5A/SF3B2/SF3B5/LSM4/SRRM2/LSM7/PRPF38B/SF3B4/RBMX2/SNRPB/MFAP1/SF3B1	12
CC	GO:0044798	nuclear transcription factor complex	36/2573	201/19717	0.02933	0.1744	0.1456	TCEA1/JUND/PPARG/PBX1/TAF4/TAF10/JUN/SFPQ/LDB1/MED8/RXRB/CREB1/GTF2H3/NFYA/THRB/TRRAP/GTF3C4/FOS/NFATC4/MAX/DDIT3/MED6/TAF3/NR1D2/KLF4/SOX9/YAP1/GTF2E1/NONO/BDP1/TAF1/E2F8/JUNB/NR1H4/NR5A2/NFATC3	36
CC	GO:0016010	dystrophin-associated glycoprotein complex	6/2573	19/19717	0.02941	0.1744	0.1456	SGCD/UTRN/SGCE/SSPN/SGCB/DMD	6
CC	GO:0031362	anchored component of external side of plasma membrane	6/2573	19/19717	0.02941	0.1744	0.1456	CD59/CA4/GPIHBP1/THY1/IGSF21/GP1BA	6
CC	GO:0090665	glycoprotein complex	6/2573	19/19717	0.02941	0.1744	0.1456	SGCD/UTRN/SGCE/SSPN/SGCB/DMD	6
CC	GO:0098644	complex of collagen trimers	6/2573	19/19717	0.02941	0.1744	0.1456	COL27A1/COL4A1/COL4A2/COL5A1/COL5A2/COL1A2	6
CC	GO:0031674	I band	27/2573	143/19717	0.02984	0.1755	0.1466	SRI/MYL9/FHL2/SLC4A1/NEXN/PDE4B/JUP/HSPB1/OBSL1/LDB3/KCNA5/ANK1/FERMT2/ACTN1/MTM1/FLNC/FKBP1B/PPP3CB/ANK2/CSRP2/FLNA/RYR2/PDLIM4/DMD/CSRP1/CRYAB/PARVA	27
CC	GO:0000502	proteasome complex	14/2573	63/19717	0.03026	0.1764	0.1474	PSMD14/PSMD12/PSMD7/PSMB5/TXNL1/HSPB1/ZFAND2A/VCP/UBE3C/IDE/PSMB7/PSMD1/PSMD9/PSME1	14
CC	GO:0090575	RNA polymerase II transcription factor complex	30/2573	163/19717	0.03158	0.1764	0.1474	TCEA1/JUND/PPARG/PBX1/TAF4/TAF10/JUN/SFPQ/LDB1/MED8/RXRB/CREB1/GTF2H3/NFYA/THRB/TRRAP/FOS/MAX/DDIT3/MED6/TAF3/NR1D2/YAP1/GTF2E1/NONO/TAF1/E2F8/JUNB/NR1H4/NR5A2	30
CC	GO:0000790	nuclear chromatin	62/2573	377/19717	0.03165	0.1764	0.1474	MUC1/SIRT2/ARID1A/MSH6/NCOA3/JUND/ARID1B/CHRAC1/YY1/MEF2D/NIPBL/TAF4/IRF1/JUN/HAT1/CHAF1A/DHX9/CDK9/TAL1/LDB1/CREB1/ING3/BRMS1L/CREBBP/SMARCC1/THRB/IRF4/TRRAP/FOXC1/ZBTB7A/TELO2/DDX11/SIRT1/MAX/TRIM24/RELA/MTA1/PLCB1/HNRNPK/RSF1/POU4F1/KLF4/CREB3L1/NUFIP1/BPTF/RBMX/EP400/SUDS3/SIRT7/CHD5/PCGF2/SIN3B/TNKS1BP1/TAF1/KLF1/JUNB/SMARCA1/NR1H4/CDK13/SIN3A/C17orf49/NCOA1	62
CC	GO:0031414	N-terminal protein acetyltransferase complex	4/2573	10/19717	0.03167	0.1764	0.1474	NAA16/NAA30/NAA25/NAA15	4
CC	GO:0043256	laminin complex	4/2573	10/19717	0.03167	0.1764	0.1474	LAMC1/LAMC2/LAMB1/NTN4	4
CC	GO:0070938	contractile ring	4/2573	10/19717	0.03167	0.1764	0.1474	RTKN/ANLN/UTRN/MYH9	4
CC	GO:0097197	tetraspanin-enriched microdomain	4/2573	10/19717	0.03167	0.1764	0.1474	TSPAN9/SAMHD1/PDPN/TSPAN14	4
CC	GO:0031965	nuclear membrane	50/2573	296/19717	0.03261	0.1803	0.1506	IFI27/TRA2B/PHF20/SCRN1/GUCY2D/ITPR1/EDNRB/OSBPL6/NAV3/SCAI/WTAP/RNF6/SNCA/HOXA7/NUP93/AKIRIN1/RAP1GAP2/ERN1/DDX19A/MATR3/SMAD1/NUP50/DNAJB14/SIRT1/GCH1/EGFR/BCL2L1/P2RX7/NUP153/NUP210/PLCB1/SH3BGRL2/TAF3/NUP54/TMEM201/TMC6/AQP1/NUP155/YBX1/MCM3AP/PLCD4/RANGAP1/ALG14/CMTM3/TMEM43/KPNA4/EPC1/SUN2/MRGPRF/PRICKLE2	50
CC	GO:1905369	endopeptidase complex	14/2573	64/19717	0.03424	0.1873	0.1565	PSMD14/PSMD12/PSMD7/PSMB5/TXNL1/HSPB1/ZFAND2A/VCP/UBE3C/IDE/PSMB7/PSMD1/PSMD9/PSME1	14
CC	GO:0030018	Z disc	25/2573	132/19717	0.03438	0.1873	0.1565	SRI/MYL9/FHL2/SLC4A1/NEXN/PDE4B/JUP/HSPB1/OBSL1/LDB3/KCNA5/ANK1/ACTN1/FLNC/FKBP1B/PPP3CB/ANK2/CSRP2/FLNA/RYR2/PDLIM4/DMD/CSRP1/CRYAB/PARVA	25
CC	GO:0044448	cell cortex part	33/2573	184/19717	0.03508	0.189	0.1578	CTTN/EPB42/CLDN5/TMOD1/RTKN/MYADM/SLC4A1/PVALB/C2CD2L/ANLN/AKAP13/CLASP2/SHROOM4/CALD1/RAPGEF3/ASPH/COTL1/MLPH/EEF1A1/UTRN/PHLDB2/PLEKHH2/CAPZA1/CIB2/MYH9/EXOC3L2/FLNA/HCLS1/CLASP1/DLC1/UNC13B/STXBP6/CORO1A	33
CC	GO:0016323	basolateral plasma membrane	38/2573	217/19717	0.03519	0.189	0.1578	CNNM4/DSTYK/SLC4A1/STX2/ATP7B/HPGD/DLG1/SHROOM4/ADRA2A/DLG2/P2RY12/EGFR/SLC26A10/ITGA9/PDPN/ITGA3/MSN/GPIHBP1/OSCP1/PTH1R/CEACAM1/ANK1/SLC26A6/IDE/AQP1/MYO1C/PDZD11/CD34/TEK/STX4/ANK2/SLC23A1/TLR9/TJP1/ALPK2/HSP90AB1/HEPH/CD300LG	38
CC	GO:1904949	ATPase complex	20/2573	101/19717	0.03597	0.1918	0.1602	ARID1A/ARID1B/CHRAC1/YY1/RFC1/ATP1B2/ING3/ABCB6/SMARCC1/TRRAP/ZBTB7A/MTA1/VCP/RSF1/FXYD1/BPTF/EP400/CHD5/SMARCA1/C17orf49	20
CC	GO:0033290	eukaryotic 48S preinitiation complex	5/2573	15/19717	0.03662	0.1938	0.1619	EIF3L/EIF2S1/EIF3F/EIF3K/EIF3M	5
CC	GO:1905368	peptidase complex	18/2573	89/19717	0.03737	0.1957	0.1635	PSMD14/PSMD12/PSMD7/PSMB5/TXNL1/TRRAP/HSPB1/ZFAND2A/VCP/UBE3C/SPCS1/IDE/PSMB7/PSMD1/PSMD9/SPCS3/SPG7/PSME1	18
CC	GO:0031307	integral component of mitochondrial outer membrane	6/2573	20/19717	0.03751	0.1957	0.1635	TOMM20/PINK1/ABCB6/FUNDC1/ARMCX3/BAK1	6
CC	GO:0005840	ribosome	46/2573	272/19717	0.03834	0.1985	0.1658	RPS27/RPS28/MRPL36/NUFIP2/RPS27L/EIF2AK4/SNCA/DHX9/RPS15/SERP1/MRPL44/MRPL48/UBA52/RPS26/RBM3/LARP1/RPLP1/RPL28/RPS3A/MRPL15/MRPL20/RPL10/EIF2A/MRPS28/RPL29/RSL24D1/MRPS14/RPS8/RPS4Y1/RPS2/RPL39/RPS10/MRPL18/RPL6/NUFIP1/MRPL13/MRPL21/MRPL17/RPL14/RPS7/MRPL54/RPL22L1/RPL9/MRPL2/RPL15/ABCF1	46
CC	GO:0016529	sarcoplasmic reticulum	15/2573	71/19717	0.03857	0.1985	0.1658	SRI/FSD2/CAMK2G/ITPR1/RTN2/HSP90B1/NOL3/SGCD/THBS4/ASPH/ANK1/FKBP1B/MTMR12/RYR2/CMYA5	15
CC	GO:0015935	small ribosomal subunit	15/2573	72/19717	0.04306	0.2201	0.1838	RPS27/RPS28/RPS27L/RPS15/UBA52/RPS26/RPS3A/EIF2A/MRPS28/MRPS14/RPS8/RPS4Y1/RPS2/RPS10/RPS7	15
CC	GO:0005583	fibrillar collagen trimer	4/2573	11/19717	0.04473	0.224	0.1871	COL27A1/COL5A1/COL5A2/COL1A2	4
CC	GO:0031680	G-protein beta/gamma-subunit complex	4/2573	11/19717	0.04473	0.224	0.1871	GNG11/GNG12/GNGT2/GNG10	4
CC	GO:0098643	banded collagen fibril	4/2573	11/19717	0.04473	0.224	0.1871	COL27A1/COL5A1/COL5A2/COL1A2	4
CC	GO:0000123	histone acetyltransferase complex	17/2573	85/19717	0.04633	0.2301	0.1922	PHF20/POLE3/MSL2/EP300/TAF4/TAF10/YEATS2/ING3/WDR5/CREBBP/TRRAP/RSF1/MORF4L2/HCFC1/EP400/EPC1/ING5	17
CC	GO:1902562	H4 histone acetyltransferase complex	10/2573	43/19717	0.04671	0.2301	0.1922	POLE3/MSL2/YEATS2/ING3/WDR5/TRRAP/MORF4L2/HCFC1/EP400/EPC1	10
CC	GO:0031306	intrinsic component of mitochondrial outer membrane	6/2573	21/19717	0.0469	0.2301	0.1922	TOMM20/PINK1/ABCB6/FUNDC1/ARMCX3/BAK1	6
CC	GO:0071437	invadopodium	5/2573	16/19717	0.0477	0.2325	0.1942	PDPN/ITGA3/MSN/FAP/AFAP1L1	5
CC	GO:0043197	dendritic spine	30/2573	169/19717	0.04816	0.2332	0.1948	SRI/CTTN/PTPRO/ARFGEF2/DDN/FXR1/FUS/CTTNBP2/FCGR2B/PDE4B/NTRK2/ARHGAP32/CRIPT/DNM1/FARP1/STX4/CDK5R1/SHISA8/PALMD/PDLIM4/RGS14/MYH10/ARC/RAB8A/PRKAR2B/CRYAB/GIPC1/PRRT2/SYT11/SHANK3	30
CC	GO:0030176	integral component of endoplasmic reticulum membrane	27/2573	150/19717	0.05052	0.2431	0.203	SEC62/HLA-DPB1/EDEM1/DHRS9/RTN2/CPT1C/SPPL3/PDIA3/ERN1/MMGT1/RNF183/DERL1/TBL2/ELOVL7/HLA-B/DOLK/SPCS1/BSCL2/FKBP8/AUP1/SLC37A4/BNIP1/WFS1/HSPA5/SLC37A3/HLA-A/ELOVL5	27
CC	GO:0035097	histone methyltransferase complex	17/2573	86/19717	0.05099	0.2438	0.2036	PHF20/UTY/TAF4/KDM5D/KDM6B/ZNF462/WDR5/SIRT1/MAX/SETD1B/HCFC1/JARID2/REST/EZH1/TAF1/NCOA6/C17orf49	17
CC	GO:0034399	nuclear periphery	24/2573	131/19717	0.05256	0.2497	0.2086	ENC1/SRRM1/PHF5A/YY1/SPARC/AKAP8L/SFPQ/HAT1/NUP93/HNRNPM/PHB2/MATR3/TELO2/KIF4A/PML/NUP153/SATB2/MAP2/TGFB1I1/NUFIP1/SORBS1/RUNX1T1/NONO/AKAP8	24
CC	GO:0030137	COPI-coated vesicle	7/2573	27/19717	0.05349	0.2525	0.2109	ARF1/COPB2/PACSIN1/TMEM199/KDELR3/ARFGAP2/COPZ2	7
CC	GO:0033267	axon part	61/2573	382/19717	0.05407	0.2536	0.2118	SIRT2/SRI/NRCAM/SLC18A1/SCN1B/CTTN/EPS8/FGF13/KCNC4/PTPRO/MBP/ITGA4/TRAK1/PARD3/PRKCB/SNCA/DLG1/SSH1/PINK1/FKBP4/ACTR10/PACSIN1/NRP1/L1CAM/BOC/HSP90AA1/DLG2/KCNA6/TPX2/KIF4A/NTRK2/HSPB1/UCHL1/ITGA3/UTRN/CBL/NIN/MAP2/ANK1/DPYSL3/LRIG2/DNM1/GAP43/SLC32A1/POLG/KCNA1/THY1/CDK5R1/ANK2/RANGAP1/SPG7/ROR1/HSP90AB1/ADCYAP1/ITGA2/MYH10/UNC13B/PRRT2/KLC1/SYT11/KCNA3	61
CC	GO:0071005	U2-type precatalytic spliceosome	11/2573	50/19717	0.05451	0.254	0.2122	PHF5A/SF3B2/SF3B5/LSM4/SRRM2/LSM7/SF3B4/RBMX2/SNRPB/MFAP1/SF3B1	11
CC	GO:0044309	neuron spine	30/2573	171/19717	0.0549	0.2543	0.2124	SRI/CTTN/PTPRO/ARFGEF2/DDN/FXR1/FUS/CTTNBP2/FCGR2B/PDE4B/NTRK2/ARHGAP32/CRIPT/DNM1/FARP1/STX4/CDK5R1/SHISA8/PALMD/PDLIM4/RGS14/MYH10/ARC/RAB8A/PRKAR2B/CRYAB/GIPC1/PRRT2/SYT11/SHANK3	30
CC	GO:0098562	cytoplasmic side of membrane	31/2573	178/19717	0.05616	0.2585	0.2159	RPS28/SLC4A1/CDK16/PTP4A1/CAV2/DLG1/PLEKHA4/SPPL3/DNAJA1/C2CD2L/SHROOM4/RPS26/GNG11/TRAF6/JUP/STAC/CYLD/EEF1A1/STAC2/ANK1/FERMT2/PKP4/FARP1/DIABLO/GNA14/GNG12/LYN/GNGT2/GNG10/PTPRC/SHANK3	31
CC	GO:0097225	sperm midpiece	6/2573	22/19717	0.05761	0.2635	0.2201	SLC9A3R1/SQSTM1/TACR1/SLC26A6/IFT81/DEFB1	6
CC	GO:0016282	eukaryotic 43S preinitiation complex	5/2573	17/19717	0.06055	0.2729	0.2279	EIF3L/EIF1/EIF3F/EIF3K/EIF3M	5
CC	GO:0060077	inhibitory synapse	5/2573	17/19717	0.06055	0.2729	0.2279	SLC32A1/IGSF9/NLGN4X/IGSF21/SYT11	5
CC	GO:0005769	early endosome	56/2573	350/19717	0.06076	0.2729	0.2279	RABGAP1L/PTP4A2/MME/CLIP3/TRAK1/WASF2/PTP4A1/SNX19/MCOLN3/USP10/STX8/RND2/SORL1/RAB11FIP5/PTP4A3/NRP1/TGFBRAP1/PLEKHJ1/ITCH/ANKRD13B/MMGT1/FGD5/EGFR/AOC3/NTRK2/DERL1/PML/AP1AR/SLC1A1/HLA-B/TBC1D16/RIN3/STEAP2/LAPTM4B/DTX3L/WDFY2/NEURL1B/FZD5/ANK2/GPNMB/WDR91/UVRAG/VPS26B/PDLIM4/CAV1/INPP5F/SLC35D3/KDR/ARC/SAMD9L/CCDC93/MTMR4/CORO1A/HLA-A/MAGEL2/CLCN4	56
CC	GO:1902554	serine/threonine protein kinase complex	17/2573	88/19717	0.06129	0.2736	0.2285	ACVR1/CDK9/GTF2H3/CCND1/ERN1/ZBTB7A/SESN2/SMCR8/ACVR2A/CCNT2/CNTD2/CCNY/IFIT5/CDK5R1/UVRAG/PHKA1/CDK13	17
CC	GO:0031594	neuromuscular junction	15/2573	76/19717	0.0647	0.2848	0.2378	KCNC4/DLG1/CRKL/DLG2/P2RX7/PTN/UTRN/PDZRN3/CIB2/MYH9/FCHSD2/CDK5R1/POSTN/MYH10/UNC13B	15
CC	GO:0070603	SWI/SNF superfamily-type complex	15/2573	76/19717	0.0647	0.2848	0.2378	ARID1A/ARID1B/CHRAC1/YY1/ING3/SMARCC1/TRRAP/ZBTB7A/MTA1/RSF1/BPTF/EP400/CHD5/SMARCA1/C17orf49	15
CC	GO:0030666	endocytic vesicle membrane	29/2573	167/19717	0.06494	0.2848	0.2378	ANXA3/HLA-DPB1/CAMK2G/CD9/WNT5B/RAB11FIP1/UBA52/ATP6V0A2/MSR1/GRIA3/NOS3/AP2A2/HLA-B/NOSTRIN/SMO/RAB7B/HVCN1/SNAP23/STX4/FZD5/UBC/COLEC12/WNT5A/FCHO1/CAV1/FZD4/RAB8A/CORO1A/HLA-A	29
CC	GO:0016363	nuclear matrix	20/2573	109/19717	0.07094	0.3092	0.2583	ENC1/SRRM1/PHF5A/YY1/SPARC/AKAP8L/SFPQ/HAT1/HNRNPM/PHB2/MATR3/KIF4A/PML/SATB2/TGFB1I1/NUFIP1/SORBS1/RUNX1T1/NONO/AKAP8	20
CC	GO:0150034	distal axon	46/2573	285/19717	0.07351	0.3151	0.2632	SIRT2/SRI/SLC18A1/CTTN/EPS8/FGF13/KCNC4/PTPRO/ITGA4/TRAK1/PARD3/PRKCB/SNCA/SSH1/PINK1/FKBP4/PACSIN1/NRP1/L1CAM/BOC/HSP90AA1/KCNA6/NTRK2/ITGA3/UTRN/CBL/NIN/MAP2/DPYSL3/LRIG2/GAP43/SLC32A1/POLG/KCNA1/THY1/CDK5R1/ROR1/HSP90AB1/ADCYAP1/ITGA2/MYH10/UNC13B/PRRT2/KLC1/SYT11/KCNA3	46
CC	GO:0030427	site of polarized growth	30/2573	176/19717	0.07467	0.3151	0.2632	SIRT2/CTTN/EPS8/FGF13/PTPRO/ITGA4/TRAK1/PARD3/SNCA/SSH1/PINK1/FKBP4/NRP1/L1CAM/BOC/HSP90AA1/ITGA3/UTRN/CBL/NIN/MAP2/DPYSL3/LRIG2/GAP43/THY1/CDK5R1/HSP90AB1/HCLS1/MYH10/KLC1	30
CC	GO:0016342	catenin complex	7/2573	29/19717	0.07479	0.3151	0.2632	APC/SMAD7/JUP/CDH26/CDH5/CDH6/CDH11	7
CC	GO:0044665	MLL1/2 complex	7/2573	29/19717	0.07479	0.3151	0.2632	PHF20/TAF4/WDR5/MAX/HCFC1/TAF1/C17orf49	7
CC	GO:0071339	MLL1 complex	7/2573	29/19717	0.07479	0.3151	0.2632	PHF20/TAF4/WDR5/MAX/HCFC1/TAF1/C17orf49	7
CC	GO:0016459	myosin complex	13/2573	65/19717	0.07484	0.3151	0.2632	MYL9/MYL6B/MYL4/ACTG2/BMF/MYO1C/MYH9/MYH10/DYNLL2/CGNL1/LIMCH1/MYO5C/MYO15A	13
CC	GO:0032279	asymmetric synapse	52/2573	328/19717	0.07793	0.3263	0.2725	NRCAM/RPS27/EPS8/PDPK1/ITPR1/PTPRO/ARF1/BCL11A/ARFGEF2/DLG1/FABP5/FXR1/PHB2/PSD3/NEFH/DLG2/PDE4B/GRIP2/KPNA1/NTRK2/ARHGAP32/PRR7/MAP2/CRIPT/GRASP/EFNB2/PKP4/DNM1/CPEB1/GAP43/RPL6/DCLK1/CDK5R1/MPDZ/SHISA8/PAK3/MAGI2/HNRNPH2/DGKZ/RPL14/NLGN4X/LYN/RGS14/DYNLL2/ARC/PCBP2/RAB8A/CRYAB/BCAS1/PRRT2/SYT11/SHANK3	52
CC	GO:0044292	dendrite terminus	4/2573	13/19717	0.07847	0.3267	0.2729	HSP90AA1/MAP2/SLC32A1/HSP90AB1	4
CC	GO:0098984	neuron to neuron synapse	55/2573	350/19717	0.0813	0.3365	0.2811	NRCAM/RPS27/EPS8/PDPK1/ITPR1/PTPRO/ARF1/BCL11A/ARFGEF2/DLG1/FABP5/FXR1/PHB2/PSD3/NEFH/DLG2/PDE4B/GRIP2/KPNA1/NTRK2/YWHAZ/ARHGAP32/PRR7/MAP2/CRIPT/GRASP/EFNB2/PKP4/DNM1/CPEB1/GAP43/RPL6/DCLK1/CDK5R1/MPDZ/SHISA8/PAK3/MAGI2/HNRNPH2/DGKZ/RPL14/NLGN4X/LYN/RGS14/DYNLL2/ARC/PCBP2/RAB8A/UNC13B/CRYAB/BCAS1/PRRT2/RAPGEF4/SYT11/SHANK3	55
CC	GO:0030426	growth cone	29/2573	171/19717	0.08267	0.3382	0.2825	SIRT2/CTTN/EPS8/FGF13/PTPRO/ITGA4/TRAK1/PARD3/SNCA/SSH1/PINK1/FKBP4/NRP1/L1CAM/BOC/HSP90AA1/ITGA3/UTRN/CBL/NIN/MAP2/DPYSL3/LRIG2/GAP43/THY1/CDK5R1/HSP90AB1/MYH10/KLC1	29
CC	GO:0022624	proteasome accessory complex	6/2573	24/19717	0.08307	0.3382	0.2825	PSMD14/PSMD12/PSMD7/PSMD1/PSMD9/PSME1	6
CC	GO:0031233	intrinsic component of external side of plasma membrane	6/2573	24/19717	0.08307	0.3382	0.2825	CD59/CA4/GPIHBP1/THY1/IGSF21/GP1BA	6
CC	GO:0005681	spliceosomal complex	31/2573	185/19717	0.08485	0.3424	0.286	TRA2B/SRRM1/PHF5A/SF3B2/SF3B5/LSM4/RBM22/PPIL1/SYF2/SRRM2/HNRNPM/LSM7/PRPF38B/SF3B4/U2AF1L4/RBM3/RBMX2/CWC25/RBMXL1/U2AF1/WAC/ZCCHC8/HNRNPK/SNRPB/YBX1/MFAP1/SF3B1/RBMX/SMNDC1/CDC5L/ZNF830	31
CC	GO:0031227	intrinsic component of endoplasmic reticulum membrane	27/2573	158/19717	0.08502	0.3424	0.286	SEC62/HLA-DPB1/EDEM1/DHRS9/RTN2/CPT1C/SPPL3/PDIA3/ERN1/MMGT1/RNF183/DERL1/TBL2/ELOVL7/HLA-B/DOLK/SPCS1/BSCL2/FKBP8/AUP1/SLC37A4/BNIP1/WFS1/HSPA5/SLC37A3/HLA-A/ELOVL5	27
CC	GO:0005719	nuclear euchromatin	7/2573	30/19717	0.08705	0.3487	0.2913	JUN/CREB1/SIRT1/TRIM24/KLF4/RBMX/NR1H4	7
CC	GO:0014069	postsynaptic density	51/2573	324/19717	0.08823	0.3515	0.2936	NRCAM/RPS27/EPS8/PDPK1/ITPR1/PTPRO/ARF1/BCL11A/DLG1/FABP5/FXR1/PHB2/PSD3/NEFH/DLG2/PDE4B/GRIP2/KPNA1/NTRK2/ARHGAP32/PRR7/MAP2/CRIPT/GRASP/EFNB2/PKP4/DNM1/CPEB1/GAP43/RPL6/DCLK1/CDK5R1/MPDZ/SHISA8/PAK3/MAGI2/HNRNPH2/DGKZ/RPL14/NLGN4X/LYN/RGS14/DYNLL2/ARC/PCBP2/RAB8A/CRYAB/BCAS1/PRRT2/SYT11/SHANK3	51
CC	GO:0043034	costamere	5/2573	19/19717	0.09151	0.3626	0.3029	FXR1/AHNAK/FLNC/ANK2/DMD	5
CC	GO:0005802	trans-Golgi network	38/2573	236/19717	0.09866	0.384	0.3208	PLD4/COG3/OSBP/VPS53/CHST1/MME/HLA-DPB1/YIPF6/ARF1/CLIP3/ATP7B/RAB13/ARFGEF2/CABP7/STX16/STX8/KLHL20/SORL1/PLEKHJ1/CLASP2/PAM/WDR11/AFTPH/CA4/SLC24A5/CHST3/SLC10A7/RAB7B/RAB12/STX4/TBC1D23/ARFGAP2/SYS1/POSTN/RAB8A/AP1S3/AP4E1/SCOC	38
CC	GO:0005744	TIM23 mitochondrial import inner membrane translocase complex	4/2573	14/19717	0.09895	0.384	0.3208	TIMM23/TIMM10/SLC25A6/GRPEL1	4
CC	GO:0043218	compact myelin	4/2573	14/19717	0.09895	0.384	0.3208	SIRT2/MBP/MPP5/MPDZ	4
CC	GO:0044304	main axon	13/2573	68/19717	0.0995	0.384	0.3208	SIRT2/NRCAM/SCN1B/MBP/PARD3/DLG1/DLG2/MAP2/ANK1/DNM1/KCNA1/THY1/ANK2	13
CC	GO:0000152	nuclear ubiquitin ligase complex	9/2573	43/19717	0.09997	0.384	0.3208	BCOR/CBX4/UBE2S/BUB1B/ANAPC10/PHC3/UBE2C/PCGF2/BARD1	9
CC	GO:0009898	cytoplasmic side of plasma membrane	26/2573	154/19717	0.1	0.384	0.3208	SLC4A1/CDK16/PTP4A1/CAV2/DLG1/PLEKHA4/C2CD2L/SHROOM4/GNG11/TRAF6/JUP/STAC/CYLD/STAC2/ANK1/FERMT2/PKP4/FARP1/DIABLO/GNA14/GNG12/LYN/GNGT2/GNG10/PTPRC/SHANK3	26
CC	GO:0031463	Cul3-RING ubiquitin ligase complex	8/2573	37/19717	0.1008	0.3852	0.3217	ENC1/PEF1/KEAP1/DEPDC5/KLHL15/KLHL20/ARIH1/TNFAIP1	8
CC	GO:0030133	transport vesicle	60/2573	392/19717	0.1048	0.3983	0.3327	SLC18A1/GOLGA5/NTF3/AMPH/SYTL4/MME/PEF1/HLA-DPB1/ITPR1/CDK16/STX2/BDNF/MFF/CNIH3/SNCA/CAV2/CD59/STX16/COPB2/RAB11FIP5/CTTNBP2/ICA1/ERP29/PAM/PDE4B/SLC2A8/BCL2L1/AFTPH/SEC16A/CPE/IGF1/CA4/AP1AR/HLA-B/CEACAM1/BGN/BET1/DPYSL3/SYTL1/SEC24B/SSPN/DNM1/STEAP2/SLC32A1/GOSR1/STX4/IL33/KDELR3/SYPL2/SLC17A5/WFS1/RAB8A/NRSN2/UNC13B/GIPC1/ROGDI/PRRT2/COPZ2/HLA-A/SYT11	60
CC	GO:0061695	transferase complex, transferring phosphorus-containing groups	41/2573	259/19717	0.1086	0.4057	0.3389	SOCS7/ACVR1/TCEA1/PRIM2/CHRAC1/POLE3/PRKAR2A/TAF4/TAF10/CDK9/GTF2H3/RPRD2/CCND1/ERN1/IGF1R/TRRAP/ZBTB7A/POLE/SESN2/SETD5/SMCR8/ACVR2A/MAP3K5/CCNT2/POLR2G/TAF3/PIK3CD/CNTD2/CCNY/IFIT5/PRKAG2/POLG/GTF2E1/SORBS1/CDK5R1/UVRAG/TAF1/POLR2D/PHKA1/CDK13/PFKP	41
CC	GO:0014704	intercalated disc	10/2573	50/19717	0.1092	0.4057	0.3389	SCN1B/FGF13/DLG1/GJA5/JUP/OBSL1/KCNA5/ACTN1/FXYD1/ANK2	10
CC	GO:0030663	COPI-coated vesicle membrane	5/2573	20/19717	0.1095	0.4057	0.3389	COPB2/TMEM199/KDELR3/ARFGAP2/COPZ2	5
CC	GO:0035267	NuA4 histone acetyltransferase complex	5/2573	20/19717	0.1095	0.4057	0.3389	ING3/TRRAP/MORF4L2/EP400/EPC1	5
CC	GO:0043189	H4/H2A histone acetyltransferase complex	5/2573	20/19717	0.1095	0.4057	0.3389	ING3/TRRAP/MORF4L2/EP400/EPC1	5
CC	GO:0005795	Golgi stack	25/2573	149/19717	0.1109	0.4087	0.3414	COG3/GOLGA5/CIT/SCFD1/MBTPS1/YIPF6/TMEM87A/CLIP3/ASAP2/B4GALT2/GALNT3/STX16/SORL1/SMPD3/TMEM115/BET1/SULF1/SLC10A7/MGAT2/PLK3/GOSR1/MAN2A1/GOLGA3/ST6GAL1/B4GALT4	25
CC	GO:0022625	cytosolic large ribosomal subunit	12/2573	63/19717	0.1128	0.4138	0.3456	UBA52/RPLP1/RPL28/RPL10/RPL29/RSL24D1/RPL39/RPL6/RPL14/RPL22L1/RPL9/RPL15	12
CC	GO:0030867	rough endoplasmic reticulum membrane	6/2573	26/19717	0.1138	0.4149	0.3465	RPS28/SEC61B/PLOD2/RPS26/ZC3H12A/DERL1	6
CC	GO:0031941	filamentous actin	7/2573	32/19717	0.1148	0.4149	0.3465	SMTNL2/LDB3/DPYSL3/MYO1C/SMTN/NCKAP1/PDLIM4	7
CC	GO:0042788	polysomal ribosome	7/2573	32/19717	0.1148	0.4149	0.3465	RPS28/NUFIP2/DHX9/RPS26/LARP1/RPL39/RPL6	7
CC	GO:0031985	Golgi cisterna	20/2573	116/19717	0.1162	0.4163	0.3478	COG3/GOLGA5/CIT/SCFD1/YIPF6/TMEM87A/ASAP2/B4GALT2/GALNT3/STX16/SORL1/SMPD3/TMEM115/BET1/SLC10A7/GOSR1/MAN2A1/GOLGA3/ST6GAL1/B4GALT4	20
CC	GO:0000315	organellar large ribosomal subunit	11/2573	57/19717	0.1169	0.4163	0.3478	MRPL36/MRPL44/MRPL48/MRPL15/MRPL20/MRPL18/MRPL13/MRPL21/MRPL17/MRPL54/MRPL2	11
CC	GO:0005762	mitochondrial large ribosomal subunit	11/2573	57/19717	0.1169	0.4163	0.3478	MRPL36/MRPL44/MRPL48/MRPL15/MRPL20/MRPL18/MRPL13/MRPL21/MRPL17/MRPL54/MRPL2	11
CC	GO:0000922	spindle pole	27/2573	164/19717	0.1194	0.4172	0.3485	RASSF1/BEX4/KATNAL2/YPEL5/PPP2CA/UNC119/DYNC1I1/LRMP/TPX2/DDX11/HAUS8/ODF2/RAE1/NIN/TMEM201/PKP4/PLK3/PLK1/FAM110A/NEDD9/NDE1/EML1/KATNAL1/RGS14/DCTN4/KATNA1/NEK2	27
CC	GO:0070820	tertiary granule	27/2573	164/19717	0.1194	0.4172	0.3485	HBB/CHIT1/ORM1/CLEC4C/MMP8/STOM/CD177/YPEL5/OLFM4/PGLYRP1/LTF/CD59/CRISP3/DIAPH1/CAMP/AP2A2/UBR4/HP/CEACAM8/CEACAM1/MMP9/TMC6/TSPAN14/SNAP23/CXCL1/CD300A/PTPRB	27
CC	GO:0005684	U2-type spliceosomal complex	16/2573	90/19717	0.1216	0.4172	0.3485	PHF5A/SF3B2/SF3B5/LSM4/RBM22/PPIL1/SYF2/SRRM2/LSM7/SF3B4/RBMX2/CWC25/SNRPB/MFAP1/SF3B1/CDC5L	16
CC	GO:0000778	condensed nuclear chromosome kinetochore	4/2573	15/19717	0.1216	0.4172	0.3485	CENPO/MIS12/BUB1B/PLK1	4
CC	GO:0005639	integral component of nuclear inner membrane	4/2573	15/19717	0.1216	0.4172	0.3485	P2RX7/TMEM201/TMEM43/SUN2	4
CC	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex	4/2573	15/19717	0.1216	0.4172	0.3485	POLE3/YEATS2/WDR5/HCFC1	4
CC	GO:0031229	intrinsic component of nuclear inner membrane	4/2573	15/19717	0.1216	0.4172	0.3485	P2RX7/TMEM201/TMEM43/SUN2	4
CC	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane	4/2573	15/19717	0.1216	0.4172	0.3485	RPS28/SPPL3/DNAJA1/RPS26	4
CC	GO:0005637	nuclear inner membrane	11/2573	58/19717	0.1282	0.4362	0.3643	IFI27/TRA2B/ITPR1/ERN1/MATR3/SMAD1/SIRT1/P2RX7/TMEM201/TMEM43/SUN2	11
CC	GO:0044291	cell-cell contact zone	13/2573	71/19717	0.1286	0.4362	0.3643	SCN1B/FGF13/DLG1/GJA5/FLCN/JUP/OBSL1/KCNA5/AHNAK/ACTN1/PKP4/FXYD1/ANK2	13
CC	GO:0005838	proteasome regulatory particle	5/2573	21/19717	0.1291	0.4362	0.3643	PSMD14/PSMD12/PSMD7/PSMD1/PSMD9	5
CC	GO:0005686	U2 snRNP	6/2573	27/19717	0.131	0.4362	0.3643	PHF5A/SF3B2/SF3B5/RBMX2/SNRPB/SF3B1	6
CC	GO:0016461	unconventional myosin complex	3/2573	10/19717	0.1319	0.4362	0.3643	MYL6B/MYO1C/DYNLL2	3
CC	GO:0036513	Derlin-1 retrotranslocation complex	3/2573	10/19717	0.1319	0.4362	0.3643	DERL1/VCP/RNF139	3
CC	GO:0044224	juxtaparanode region of axon	3/2573	10/19717	0.1319	0.4362	0.3643	SIRT2/DLG2/KCNA1	3
CC	GO:0097470	ribbon synapse	3/2573	10/19717	0.1319	0.4362	0.3643	PACSIN1/DNM1/UNC13B	3
CC	GO:0046658	anchored component of plasma membrane	11/2573	59/19717	0.14	0.4611	0.3851	CD59/GAS1/RTN4RL1/GPC4/CA4/GPIHBP1/GPC6/THY1/GPC1/IGSF21/GP1BA	11
CC	GO:0005852	eukaryotic translation initiation factor 3 complex	4/2573	16/19717	0.1463	0.4721	0.3943	EIF3L/EIF3F/EIF3K/EIF3M	4
CC	GO:0042575	DNA polymerase complex	4/2573	16/19717	0.1463	0.4721	0.3943	CHRAC1/POLE3/POLE/POLG	4
CC	GO:0044453	nuclear membrane part	4/2573	16/19717	0.1463	0.4721	0.3943	P2RX7/TMEM201/TMEM43/SUN2	4
CC	GO:0070822	Sin3-type complex	4/2573	16/19717	0.1463	0.4721	0.3943	BRMS1L/SUDS3/SIN3B/SIN3A	4
CC	GO:0005790	smooth endoplasmic reticulum	7/2573	34/19717	0.1465	0.4721	0.3943	SRI/HYOU1/ERP29/RPL10/RYR2/PGRMC1/HSPA5	7
CC	GO:0031430	M band	6/2573	28/19717	0.1494	0.4739	0.3958	LRRC39/OBSL1/ANK1/ANK2/CMYA5/CRYAB	6
CC	GO:0016460	myosin II complex	5/2573	22/19717	0.1501	0.4739	0.3958	MYL9/MYL6B/MYH9/MYH10/LIMCH1	5
CC	GO:0042629	mast cell granule	5/2573	22/19717	0.1501	0.4739	0.3958	BTK/CBL/PIK3CD/SNAP23/LYN	5
CC	GO:0097038	perinuclear endoplasmic reticulum	5/2573	22/19717	0.1501	0.4739	0.3958	CLU/OSBP/OSBPL6/OSBP2/NOX4	5
CC	GO:0032592	integral component of mitochondrial membrane	13/2573	73/19717	0.1503	0.4739	0.3958	TIMM23/SLC25A3/TOMM20/MFF/PINK1/ABCB6/ETFDH/TMEM177/COX16/FUNDC1/ARMCX3/SPG7/BAK1	13
CC	GO:0043025	neuronal cell body	73/2573	497/19717	0.1514	0.4753	0.3971	SIRT2/CNNM4/ANXA3/SCN1B/CIT/KCNC4/PDPK1/MME/MBP/ITGA4/ARG1/PARD3/SNCA/DDN/TGFB2/FXR1/SLC1A3/TGFB1/PVALB/RTN4RL1/FKBP4/FUS/CYGB/NRP1/L1CAM/KCNN3/CX3CL1/HSP90AA1/TPX2/UBXN1/PAM/ARHGEF7/KCND3/P2RX7/UCHL1/CPE/ASS1/SLC25A27/PTPRF/MAP2/CRIPT/LRIG2/TTLL7/PLK3/HCFC1/KCNA1/PDE1A/THY1/FZD5/CDK5R1/TRPM5/GLRX5/FLNA/NDN/HSP90AB1/PGRMC1/INPP5F/MTOR/ADCYAP1/MYH10/ARC/RAB8A/NRSN2/PRKAR2B/ATXN10/STAU1/CRYAB/EPHB2/ROGDI/KCNK1/ELOVL5/NQO1/GDI1	73
CC	GO:0031201	SNARE complex	9/2573	47/19717	0.152	0.4753	0.3971	STX2/STX16/STX8/BET1/SNAP23/GOSR1/STX4/BNIP1/NAPG	9
CC	GO:0071013	catalytic step 2 spliceosome	15/2573	87/19717	0.1573	0.4897	0.409	SRRM1/SF3B2/RBM22/PPIL1/SYF2/SRRM2/HNRNPM/LSM7/U2AF1/ZCCHC8/HNRNPK/SNRPB/SF3B1/RBMX/CDC5L	15
CC	GO:0000776	kinetochore	22/2573	135/19717	0.1593	0.494	0.4126	HJURP/APC/DYNC1I1/CENPO/MTBP/CLASP2/SPC25/SPC24/MIS12/BUB1B/CSNK1A1/NUP160/PLK1/KIF2C/RANGAP1/NDE1/TTK/CLASP1/DCTN4/SIN3A/NEK2/RASSF2	22
CC	GO:0098573	intrinsic component of mitochondrial membrane	13/2573	74/19717	0.1618	0.4997	0.4174	TIMM23/SLC25A3/TOMM20/MFF/PINK1/ABCB6/ETFDH/TMEM177/COX16/FUNDC1/ARMCX3/SPG7/BAK1	13
CC	GO:0099572	postsynaptic specialization	52/2573	348/19717	0.1639	0.4997	0.4174	NRCAM/RPS27/EPS8/PDPK1/ITPR1/PTPRO/ARF1/BCL11A/DLG1/FABP5/FXR1/PHB2/PSD3/NEFH/DLG2/PDE4B/GRIP2/KPNA1/KCND3/NTRK2/ARHGAP32/PRR7/MAP2/CRIPT/GRASP/EFNB2/PKP4/DNM1/CPEB1/GAP43/RPL6/DCLK1/CDK5R1/MPDZ/SHISA8/PAK3/MAGI2/HNRNPH2/DGKZ/RPL14/NLGN4X/LYN/RGS14/DYNLL2/ARC/PCBP2/RAB8A/CRYAB/BCAS1/PRRT2/SYT11/SHANK3	52
CC	GO:0002116	semaphorin receptor complex	3/2573	11/19717	0.1645	0.4997	0.4174	PLXNA3/NRP1/PLXNA1	3
CC	GO:0043220	Schmidt-Lanterman incisure	3/2573	11/19717	0.1645	0.4997	0.4174	SIRT2/MPP5/MPDZ	3
CC	GO:0061827	sperm head	3/2573	11/19717	0.1645	0.4997	0.4174	TACR1/HSP90AB1/DDX6	3
CC	GO:0090568	nuclear transcriptional repressor complex	6/2573	29/19717	0.1689	0.5108	0.4266	SIRT2/ZBTB7A/SIRT1/MTA1/TBX15/CHD5	6
CC	GO:0046930	pore complex	5/2573	23/19717	0.1724	0.5137	0.4291	PLEKHA7/PDZD11/CD34/SPG7/BAK1	5
CC	GO:0031143	pseudopodium	4/2573	17/19717	0.1726	0.5137	0.4291	RAF1/LDB3/MSN/ACTN1	4
CC	GO:0035859	Seh1-associated complex	4/2573	17/19717	0.1726	0.5137	0.4291	RRAGA/DEPDC5/SESN2/SESN3	4
CC	GO:0097440	apical dendrite	4/2573	17/19717	0.1726	0.5137	0.4291	CLU/OSBP2/MAP2/FLNA	4
CC	GO:0044306	neuron projection terminus	22/2573	138/19717	0.186	0.5512	0.4604	SRI/SLC18A1/KCNC4/MME/PRKCB/SNCA/PACSIN1/KCNA6/GCH1/NTRK2/UCHL1/SLC32A1/POLG/KCNA1/ROR1/ADCYAP1/ITGA2/DMD/UNC13B/PRRT2/SYT11/KCNA3	22
CC	GO:0071007	U2-type catalytic step 2 spliceosome	6/2573	30/19717	0.1893	0.5589	0.4669	RBM22/PPIL1/SYF2/SRRM2/SNRPB/CDC5L	6
CC	GO:0016235	aggresome	8/2573	43/19717	0.1913	0.5626	0.4699	EDEM1/SQSTM1/STRADB/SFMBT2/TDP2/HOXC9/RANGAP1/RNF32	8
CC	GO:0032155	cell division site part	11/2573	63/19717	0.1928	0.5648	0.4717	CIT/RTKN/RAB11FIP4/SSH1/ANLN/KIF20A/MYH9/PKN2/HMCN1/NDE1/MYH10	11
CC	GO:0000812	Swr1 complex	3/2573	12/19717	0.1993	0.5699	0.476	ING3/TRRAP/EP400	3
CC	GO:0017119	Golgi transport complex	3/2573	12/19717	0.1993	0.5699	0.476	COG3/TMEM115/GOLGA3	3
CC	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex	3/2573	12/19717	0.1993	0.5699	0.476	CDK9/CCNT2/CDK13	3
CC	GO:0032009	early phagosome	3/2573	12/19717	0.1993	0.5699	0.476	TLR9/UNC13B/SYT11	3
CC	GO:0048188	Set1C/COMPASS complex	3/2573	12/19717	0.1993	0.5699	0.476	WDR5/SETD1B/HCFC1	3
CC	GO:0016592	mediator complex	7/2573	37/19717	0.2009	0.5699	0.476	RBM14/MED10/MED8/MED7/MED13/MED6/MED30	7
CC	GO:0034358	plasma lipoprotein particle	7/2573	37/19717	0.2009	0.5699	0.476	CLU/LPL/APOF/SORL1/MSR1/APOC1/PLTP	7
CC	GO:1990777	lipoprotein particle	7/2573	37/19717	0.2009	0.5699	0.476	CLU/LPL/APOF/SORL1/MSR1/APOC1/PLTP	7
CC	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	15/2573	91/19717	0.2027	0.5699	0.476	CDK16/CAV2/PLEKHA4/GNG11/STAC/CYLD/STAC2/FERMT2/FARP1/GNA14/GNG12/LYN/GNGT2/GNG10/SHANK3	15
CC	GO:0035578	azurophil granule lumen	15/2573	91/19717	0.2027	0.5699	0.476	CTSG/ARG1/AGA/FABP5/VAT1/ELANE/ACTR10/C6orf120/RNASE3/VCP/CCT8/SERPINA3/PSMD1/PYGB/PRSS2	15
CC	GO:0016328	lateral plasma membrane	10/2573	57/19717	0.2034	0.5699	0.476	IQGAP3/FGF13/PTPRO/APC/RAB13/DLG1/JUP/CEACAM1/MYO1C/DMD	10
CC	GO:0097729	9+2 motile cilium	16/2573	98/19717	0.2038	0.5699	0.476	SLC9A3R1/GAS8/CABYR/SQSTM1/TACR1/RSPH9/NME5/ODF2/SLC26A6/WDR66/DNALI1/IFT81/DNAH5/DEFB1/TCTE1/DDX6	16
CC	GO:0005766	primary lysosome	24/2573	155/19717	0.2133	0.5912	0.4939	STOM/CTSG/ARG1/AGA/RAB37/FABP5/VAT1/ELANE/ACTR10/LRMP/C6orf120/RNASE3/CEACAM6/PIGR/VCP/CEACAM8/DDOST/CCT8/SERPINA3/SNAP23/PSMD1/PYGB/PRSS2/LPCAT1	24
CC	GO:0042582	azurophil granule	24/2573	155/19717	0.2133	0.5912	0.4939	STOM/CTSG/ARG1/AGA/RAB37/FABP5/VAT1/ELANE/ACTR10/LRMP/C6orf120/RNASE3/CEACAM6/PIGR/VCP/CEACAM8/DDOST/CCT8/SERPINA3/SNAP23/PSMD1/PYGB/PRSS2/LPCAT1	24
CC	GO:0005791	rough endoplasmic reticulum	14/2573	85/19717	0.2138	0.5912	0.4939	SEC62/RPS28/SEC61B/PLOD2/SNCA/SPPL3/FKRP/RPS26/ZC3H12A/DERL1/TRAM1L1/CA4/RPL6/STAU1	14
CC	GO:0008328	ionotropic glutamate receptor complex	9/2573	51/19717	0.2148	0.5917	0.4942	EPS8/CNIH3/CPT1C/DLG1/DLG2/GRIA3/SHISA8/SHANK3/OLFM2	9
CC	GO:0005903	brush border	16/2573	99/19717	0.2156	0.5917	0.4942	EPS8/SLC9A3R1/MME/CA4/PTH1R/SLC26A6/SLC7A9/ACTN1/AQP1/MYO1C/MYH9/HSP90AB1/MYH10/ENPEP/GIPC1/KCNK1	16
CC	GO:0000118	histone deacetylase complex	10/2573	58/19717	0.2191	0.5955	0.4975	TAL1/BRMS1L/ZBTB7A/SATB2/MTA1/SUDS3/PHF21A/CHD5/SIN3B/SIN3A	10
CC	GO:0035861	site of double-strand break	10/2573	58/19717	0.2191	0.5955	0.4975	PARP3/SMC5/SAMHD1/HELB/ZBTB7A/RNF138/VCP/WDR70/ARPC2/RNF8	10
CC	GO:0005874	microtubule	60/2573	416/19717	0.2194	0.5955	0.4975	SIRT2/SPRY2/FGF13/RASSF1/MAP1LC3A/POLB/BEX4/GAS8/KATNAL2/KIF26A/NAV3/APC/STAU2/ARFGEF2/DLG1/BCL10/DYNC1I1/FKBP4/SERP1/RASSF5/CLASP2/TPX2/MDM1/KIF4A/CYLD/MTUS1/HAUS8/MTA1/CDK2AP2/ODF2/NIN/MAP2/MID1/WHAMM/TTLL7/DNM1/CCT8/PLK1/KIF2C/KIF20A/DYNLRB1/WDR47/LRRC49/HAUS2/NDE1/EML1/KATNAL1/CLASP1/DNAH5/RGS14/DYNLL2/DNAH17/RADIL/FHDC1/EML5/KATNA1/KLC1/KIF14/NEK2/LZTS2	60
CC	GO:0000791	euchromatin	7/2573	38/19717	0.2205	0.5963	0.4981	JUN/CREB1/SIRT1/TRIM24/KLF4/RBMX/NR1H4	7
MF	GO:0005201	extracellular matrix structural constituent	71/2481	163/17697	3.345e-20	3.699e-17	3.334e-17	COL9A2/LTBP1/CHI3L1/SPARC/COL6A1/LAMC1/TNXB/AGRN/VWF/PXDN/EFEMP2/COL10A1/FN1/COL16A1/LAMC2/FBN2/COL18A1/MMRN2/ELN/ECM1/NPNT/MMRN1/NID2/PCOLCE/COL27A1/COL4A1/COL4A2/BGN/SRPX2/COL14A1/DPT/THBS3/PRG4/MFAP2/COL5A1/TINAGL1/LTBP2/HAPLN1/MXRA5/CTHRC1/MATN2/EMILIN3/LAMB1/ASPN/COL12A1/COL21A1/FBLN1/DCN/EFEMP1/HMCN1/MFAP5/ACAN/OGN/CILP/VWA1/COL6A2/COL17A1/POSTN/EDIL3/FBN1/MUC3A/FMOD/SPON1/MFAP4/PRELP/MGP/TNC/LTBP4/FBLN2/COL5A2/COL1A2	71
MF	GO:0050839	cell adhesion molecule binding	119/2481	499/17697	1.801e-09	9.96e-07	8.977e-07	ITGB3/TXNDC9/CTTN/ARHGAP18/ACVR1/EIF5/OLA1/ITGB5/CLINT1/TES/CD177/PTPRO/TBC1D10A/ITGA4/OLFM4/WASF2/CD9/DLG1/CRKL/TNXB/ANLN/VWF/CTNNAL1/PTPRH/RPS26/STK24/LARP1/CX3CL1/FN1/ZC3H15/CALD1/COL16A1/RSL1D1/SPP1/THBS4/JUP/EGFR/EIF2A/PDXDC1/FNBP1L/SFRP2/NPNT/EIF4H/CPE/IGF1/CXCL12/RPL29/ITGA3/MSN/YWHAZ/PTN/ATXN2L/CDH26/UTRN/PTPRF/PAK4/HNRNPK/CBL/PHLDB2/RPS2/ITGAL/AHNAK/ACTN1/ECM2/PKP4/CCT8/EMP2/COL5A1/HCFC1/CAPZA1/RPL6/CAMLG/CIB2/MYH9/IL1B/FAP/THY1/MPP7/LAMB1/ARHGEF16/TAGLN2/CDK5R1/GPNMB/DIAPH3/PKN2/ITGB8/RANGAP1/FLNA/TJP1/HMCN1/CDH5/HSP90AB1/ITGBL1/RPL14/NLGN4X/LYN/POSTN/IGSF21/GOLGA3/KDR/EDIL3/TNKS1BP1/ITGA2/FBN1/PFN1/HSPA5/LTBP4/STXBP6/NOTCH3/GIPC1/CDH6/PTPRB/PARVA/RPL15/CDH11/DDX6/EPS8L1/PFKP/CD151	119
MF	GO:0019838	growth factor binding	46/2481	137/17697	4.986e-09	1.838e-06	1.657e-06	ITGB3/LTBP1/ACVR1/HTRA4/SEC61B/HTRA1/COL6A1/FLT1/CD109/IL1R1/IGFBP2/PXDN/NRP1/PCSK6/TWSG1/IGF1R/HTRA3/EGFR/NTRK2/ACVR2A/KAZALD1/RHBDF1/PTN/COL4A1/IGFBP4/PDGFRA/RPS2/IGFBP5/SRPX2/OSMR/LIFR/PDGFRB/COL5A1/LTBP2/TEK/GPC1/DUSP1/IL10RA/GHR/KDR/A2M/KL/LTBP4/IGFBP3/COL1A2/NLRP7	46
MF	GO:0050840	extracellular matrix binding	26/2481	57/17697	8.414e-09	2.326e-06	2.097e-06	ITGB3/SPARC/AGRN/PLEKHA2/BCAM/SPP1/ELN/ECM1/ITGA9/ITGA3/BGN/ADAMTS15/SPARCL1/SMOC1/TINAGL1/CLEC14A/CD248/GPC1/SSC5D/LRRC15/DCN/OLFML2A/SLIT2/NTN4/ITGA2/FBLN2	26
MF	GO:0005178	integrin binding	40/2481	132/17697	1.053e-06	0.000233	0.00021	ITGB3/ITGB5/CD177/CD9/TNXB/VWF/CX3CL1/FN1/COL16A1/SPP1/THBS4/EGFR/SFRP2/NPNT/IGF1/CXCL12/ITGA3/PTN/CDH26/UTRN/ACTN1/ECM2/EMP2/COL5A1/CIB2/MYH9/IL1B/FAP/THY1/LAMB1/GPNMB/ITGB8/ITGBL1/LYN/KDR/EDIL3/ITGA2/FBN1/LTBP4/CD151	40
MF	GO:0005539	glycosaminoglycan binding	56/2481	229/17697	1.607e-05	0.002962	0.002669	CFH/CTSG/NAV2/PGLYRP1/LTF/LPL/FSTL1/PCOLCE2/TNXB/RTN4RL1/AGRN/ELANE/SELP/PLA2G5/NRP1/PCSK6/FN1/LAMC2/THBS4/CCDC80/SMOC2/RPL29/PCOLCE/PTN/CXCL6/PTPRF/BGN/ADAMTS15/DPYSL3/SULF1/THBS3/ECM2/RSPO3/GREM2/COL5A1/LTBP2/HAPLN1/SFRP1/LYVE1/TREM2/GPNMB/VIT/DCN/CCL8/ACAN/SLIT2/POSTN/FBN1/PDCD5/SOD3/SLIT1/PRELP/LTBP4/PTPRC/LXN/CLEC3B	56
MF	GO:0005518	collagen binding	23/2481	67/17697	2.212e-05	0.003079	0.002776	COCH/SPARC/SMAD7/PCOLCE2/VWF/FN1/MRC2/SERPINH1/NID2/ITGA9/ITGA3/PCOLCE/MMP9/COL14A1/C1QTNF1/ECM2/SPARCL1/ASPN/LRRC15/DCN/DDR2/ITGA2/CCBE1	23
MF	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	30/2481	99/17697	2.252e-05	0.003079	0.002776	HOXB5/YY1/GATA1/BHLHE41/JUN/HOXA7/SFPQ/TAL1/BHLHE40/CREB1/ARID3B/NFYA/SMARCC1/REL/SIRT1/RELA/HOXC6/MTA1/HOXB7/FLI1/NR1D2/POU4F1/MEOX2/NR2F6/ZNF281/NONO/GZF1/HOXC5/NR1H4/NR5A2	30
MF	GO:0008201	heparin binding	44/2481	169/17697	2.506e-05	0.003079	0.002776	CFH/CTSG/NAV2/LTF/LPL/FSTL1/PCOLCE2/TNXB/RTN4RL1/ELANE/SELP/PLA2G5/NRP1/PCSK6/FN1/LAMC2/THBS4/CCDC80/SMOC2/RPL29/PCOLCE/PTN/CXCL6/PTPRF/ADAMTS15/THBS3/ECM2/RSPO3/GREM2/COL5A1/LTBP2/SFRP1/GPNMB/CCL8/SLIT2/POSTN/FBN1/PDCD5/SOD3/SLIT1/PRELP/PTPRC/LXN/CLEC3B	44
MF	GO:0045296	cadherin binding	73/2481	331/17697	4.277e-05	0.004731	0.004264	TXNDC9/CTTN/ARHGAP18/ACVR1/EIF5/OLA1/CLINT1/TES/PTPRO/TBC1D10A/OLFM4/WASF2/DLG1/CRKL/ANLN/CTNNAL1/PTPRH/RPS26/STK24/LARP1/ZC3H15/CALD1/RSL1D1/JUP/EGFR/EIF2A/PDXDC1/FNBP1L/EIF4H/RPL29/YWHAZ/ATXN2L/CDH26/PAK4/HNRNPK/CBL/PHLDB2/RPS2/AHNAK/PKP4/CCT8/HCFC1/CAPZA1/RPL6/MYH9/MPP7/ARHGEF16/TAGLN2/CDK5R1/DIAPH3/PKN2/RANGAP1/FLNA/TJP1/CDH5/HSP90AB1/RPL14/GOLGA3/KDR/TNKS1BP1/PFN1/HSPA5/STXBP6/NOTCH3/GIPC1/CDH6/PTPRB/PARVA/RPL15/CDH11/DDX6/EPS8L1/PFKP	73
MF	GO:1901681	sulfur compound binding	58/2481	250/17697	5.839e-05	0.005414	0.004879	GNMT/CFH/CTSG/NAV2/LTF/LPL/FSTL1/PCOLCE2/TNXB/RTN4RL1/AGRN/ELANE/SELP/PLA2G5/NRP1/PCSK6/DHTKD1/FN1/LAMC2/THBS4/CCDC80/SMOC2/RPL29/PCOLCE/PTN/CXCL6/PTPRF/ADAMTS15/DPYSL3/THBS3/ECM2/ILVBL/RSPO3/GREM2/COL5A1/CD34/LTBP2/SFRP1/TPK1/ACBD5/GPNMB/CCL8/RYR2/PCIF1/PANK1/SLIT2/POSTN/ITGA2/FBN1/PDCD5/SOD3/MMACHC/SLIT1/PRELP/PTPRC/LXN/CLEC3B/HMGCL	58
MF	GO:0043236	laminin binding	13/2481	29/17697	5.874e-05	0.005414	0.004879	AGRN/PLEKHA2/BCAM/ECM1/ITGA9/ITGA3/TINAGL1/GPC1/SSC5D/LRRC15/SLIT2/NTN4/ITGA2	13
MF	GO:0030020	extracellular matrix structural constituent conferring tensile strength	16/2481	41/17697	6.701e-05	0.005701	0.005138	COL9A2/COL6A1/COL10A1/COL16A1/COL18A1/COL27A1/COL4A1/COL4A2/COL14A1/COL5A1/COL12A1/COL21A1/COL6A2/COL17A1/COL5A2/COL1A2	16
MF	GO:0002162	dystroglycan binding	7/2481	10/17697	8.579e-05	0.006777	0.006108	AGRN/CLASP2/FKRP/MAP2/AGR3/CLASP1/DMD	7
MF	GO:0001158	enhancer sequence-specific DNA binding	32/2481	119/17697	0.0001592	0.01174	0.01058	HOXB5/YY1/GATA1/BHLHE41/JUN/HOXA7/SFPQ/TAL1/LDB1/BHLHE40/CREB1/ARID3B/NFYA/SMARCC1/REL/SIRT1/RELA/HOXC6/MTA1/HOXB7/FLI1/NR1D2/POU4F1/MEOX2/SOX9/NR2F6/ZNF281/NONO/GZF1/HOXC5/NR1H4/NR5A2	32
MF	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	89/2481	439/17697	0.0001725	0.01193	0.01075	KLF13/MAF/ERG/HOXB5/JUND/IER2/FOSB/MEF2D/EP300/HEYL/GATA1/NFKB2/KLF6/MLXIP/TBX5/PBX1/IRF1/FOXI1/JUN/HOXA7/ZFAT/RXRB/PBX2/CREB1/MEOX1/ARID3B/NANOG/SMAD1/IRF4/FOXC1/NFIB/FOS/REL/CEBPE/SIRT1/DDIT3/BATF/MEIS2/RELA/HOXC10/SATB2/SIX1/HOXB7/HLF/HOXD8/HNRNPK/CSRNP1/KLF10/HOXA10/FLI1/EBF3/GLIS2/POU4F1/FOXK2/MEOX2/YBX1/KLF4/CREB3L1/HCFC1/SOX9/TBX2/KLF5/NOTCH1/ZNF24/DLX3/PLAGL2/GLI3/TFAP2E/TBX15/NR3C1/REST/TBX22/RREB1/POU2F2/NDN/MSX1/NR4A2/TBX1/EBF2/SIX2/CTCFL/CDC5L/JUNB/ETV1/NR1H4/FOXJ2/NR5A2/NFATC3/EBF1	89
MF	GO:0097493	structural molecule activity conferring elasticity	7/2481	11/17697	0.0002072	0.01324	0.01193	LAMC1/FBN2/ELN/AHNAK/EMILIN3/FBN1/FBLN2	7
MF	GO:0035257	nuclear hormone receptor binding	38/2481	152/17697	0.0002154	0.01324	0.01193	TRIP6/ARID1A/GRIP1/NCOA3/JUND/FHL2/PPARG/EP300/RNF6/TACC1/PRKCB/KDM5D/TAF10/FKBP4/PHB2/FUS/PPID/MED13/ZBTB7A/SIRT1/JUP/TRIM24/DDX54/TGFB1I1/PRAME/MED30/NSD1/JMJD1C/NCOA2/NR4A2/SLC30A9/TACC2/TAF1/RERG/NCOA6/NR1H4/CNOT1/NCOA1	38
MF	GO:0035326	enhancer binding	34/2481	133/17697	0.000289	0.01648	0.01486	HOXB5/YY1/GATA1/BHLHE41/JUN/HOXA7/SFPQ/TAL1/LDB1/BHLHE40/CREB1/TIPARP/ARID3B/NFYA/SMARCC1/REL/SIRT1/RELA/HOXC6/MTA1/HOXB7/FLI1/NR1D2/POU4F1/MEOX2/SOX9/NR2F6/ZNF281/NONO/MSX1/GZF1/HOXC5/NR1H4/NR5A2	34
MF	GO:0002020	protease binding	33/2481	128/17697	0.0002981	0.01648	0.01486	ITGB3/SRI/CRADD/TNFAIP3/CD177/MBP/FADD/TNF/BCL10/NOL3/IL1R1/PINK1/ELANE/LCN2/VWF/FN1/BDKRB2/ECM1/DERL1/ITGA3/VCP/TIMP3/SERPINB9/POLG/FAP/TIMP4/CDK5R1/UBC/RNF139/A2M/CCBE1/COL1A2/NLRP7	33
MF	GO:0017016	Ras GTPase binding	85/2481	429/17697	0.0005136	0.02705	0.02438	EPS8/GOLGA5/IQGAP3/RABGAP1L/SYTL4/SH3BP5L/GAS8/TBC1D10A/RTKN/RGL1/NXT1/RAB11FIP4/ARHGEF37/PARD6G/RAB3IL1/IPO9/SRGAP1/RAB11FIP1/DAAM2/RAB11FIP5/ANLN/FMNL1/AKAP13/RASSF5/IPO7/DIAPH1/RAB3GAP2/RAPGEF3/NUP50/ARHGEF7/FGD5/VAV1/SMCR8/RABGGTB/PLEKHG5/MLPH/EGF/ITSN2/PAK4/DENND2A/RGL3/TBC1D16/SYTL1/RIN3/WHAMM/WASF1/FARP1/MYO1C/RAPGEF5/PKN3/ARHGEF16/CHML/DENND4B/DIAPH3/NCKAP1/PKN2/RANGAP1/VAV3/IPO5/FGD3/PAK3/USP33/FLNA/PARD6A/SOS2/CAV1/TBC1D2B/MADD/ACAP2/TNFAIP1/TBC1D9/RAB8A/PFN1/MYCBP2/UNC13B/MAPKAP1/CDC42EP5/ARHGEF12/STXBP6/DOCK11/ARHGEF15/RAPGEF4/PARD6B/EPS8L1/GDI1	85
MF	GO:0046625	sphingolipid binding	10/2481	23/17697	0.0005731	0.02759	0.02487	CLIP3/PLEKHA3/PHB2/SELP/IL2/LAPTM4B/CD300LF/GLTP/LYN/PLTP	10
MF	GO:0031267	small GTPase binding	87/2481	443/17697	0.0005953	0.02759	0.02487	EPS8/GOLGA5/IQGAP3/RABGAP1L/SYTL4/SH3BP5L/GAS8/TBC1D10A/RTKN/RGL1/NXT1/RAB11FIP4/ARHGEF37/PARD6G/RAB3IL1/IPO9/SRGAP1/SORL1/RAB11FIP1/DAAM2/RAB11FIP5/ANLN/FMNL1/AKAP13/RASSF5/IPO7/DIAPH1/RAB3GAP2/RAPGEF3/NUP50/ARHGEF7/FGD5/VAV1/SMCR8/RABGGTB/PLEKHG5/MLPH/EGF/ITSN2/PAK4/DENND2A/GRASP/RGL3/TBC1D16/SYTL1/RIN3/WHAMM/WASF1/FARP1/MYO1C/RAPGEF5/PKN3/ARHGEF16/CHML/DENND4B/DIAPH3/NCKAP1/PKN2/RANGAP1/VAV3/IPO5/FGD3/PAK3/USP33/FLNA/PARD6A/SOS2/CAV1/TBC1D2B/MADD/ACAP2/TNFAIP1/TBC1D9/RAB8A/PFN1/MYCBP2/UNC13B/MAPKAP1/CDC42EP5/ARHGEF12/STXBP6/DOCK11/ARHGEF15/RAPGEF4/PARD6B/EPS8L1/GDI1	87
MF	GO:0001968	fibronectin binding	11/2481	27/17697	0.0005987	0.02759	0.02487	ITGB3/ITGA4/PLEKHA2/SFRP2/CCDC80/ITGA3/IGFBP5/SSC5D/LRRC15/FBLN1/IGFBP3	11
MF	GO:0044389	ubiquitin-like protein ligase binding	64/2481	308/17697	0.000684	0.02916	0.02628	CLU/RRAGA/GABARAPL2/UBXN7/MAP1LC3A/BAG4/NFKBIA/APC/SLC25A5/PRKAR2A/SQSTM1/SMAD7/JUN/BCL10/DNAJA1/STX8/PINK1/MOAP1/TRAF4/UBA52/ITCH/FBXW7/ERLIN1/HSP90AA1/PARP9/UBXN1/USP7/TRAF6/EGFR/JAK1/DERL1/ERLIN2/UCHL1/PML/RELA/YWHAZ/VCP/PRR7/MID1/FANCL/TNFRSF14/LAPTM4B/DTX3L/DIO2/UBE2C/CAMLG/PSMD1/FZD5/UBC/UBE2D3/RANGAP1/ARIH1/HSP90AB1/LYN/FZD4/PCBP2/WFS1/HSPA5/PRKAR2B/PER1/HSPA9/SYT11/CUL1/RNF8	64
MF	GO:0017048	Rho GTPase binding	41/2481	177/17697	0.0006854	0.02916	0.02628	EPS8/IQGAP3/RTKN/ARHGEF37/PARD6G/SRGAP1/DAAM2/ANLN/FMNL1/AKAP13/DIAPH1/ARHGEF7/FGD5/VAV1/PLEKHG5/ITSN2/PAK4/WHAMM/WASF1/FARP1/PKN3/ARHGEF16/DIAPH3/NCKAP1/PKN2/VAV3/FGD3/PAK3/FLNA/PARD6A/SOS2/CAV1/TNFAIP1/PFN1/CDC42EP5/ARHGEF12/STXBP6/DOCK11/ARHGEF15/PARD6B/EPS8L1	41
MF	GO:0016922	nuclear receptor binding	9/2481	20/17697	0.0008004	0.03279	0.02955	ARID1A/NCOA3/JUND/TACC1/TRIM24/NCOA2/SLC30A9/NR1H4/NCOA1	9
MF	GO:0005351	carbohydrate:proton symporter activity	6/2481	10/17697	0.0009537	0.03767	0.03395	SLC2A8/SLC45A1/SLC2A6/SLC2A10/SLC2A12/SLC17A5	6
MF	GO:0017147	Wnt-protein binding	13/2481	37/17697	0.001036	0.03951	0.03561	LRP5L/PTPRO/SFRP2/EGF/FZD10/SFRP4/CTHRC1/SFRP1/FZD5/ROR1/FZD4/LRP5/AXL	13
MF	GO:0046965	retinoid X receptor binding	8/2481	17/17697	0.001098	0.04049	0.0365	PPARG/TACC1/FUS/NSD1/NR4A2/NCOA6/NR1H4/NCOA1	8
MF	GO:0046332	SMAD binding	22/2481	80/17697	0.001159	0.04134	0.03726	ACVR1/YY1/USP9Y/SMAD7/JUN/TGFBRAP1/IPO7/SMAD1/BMP2/ZBTB7A/FOS/DAB2/PML/ACVR2A/SKIL/TGFB1I1/PPM1A/CREB3L1/FLNA/MAGI2/COL5A2/COL1A2	22
MF	GO:0043021	ribonucleoprotein complex binding	32/2481	133/17697	0.001305	0.0451	0.04065	OLA1/EIF5A/PELO/EIF4B/NAA16/DHX9/ITCH/EIF2S1/RBM3/LARP1/RPLP1/NOLC1/EIF1/ZC3H12A/YTHDF1/PQBP1/EIF2A/IFIH1/EIF4H/NEAT1/SNRPB/CPEB1/SMG6/YTHDF3/EIF3K/MTOR/HSPA5/UHMK1/SRP54/ABCE1/NAA15/CPEB2	32
MF	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	51/2481	242/17697	0.001653	0.05529	0.04983	ETV7/ZNF589/PPARG/YY1/IRX2/IRF8/HEYL/BCL11A/BHLHE41/SARNP/CUX2/BHLHE40/IFI16/HES6/HES1/ZBTB7A/BCL6B/NFATC4/MAX/SP3/SKIL/RELA/ZBTB2/HIC2/NR1D2/FOXS1/PRRX1/PCBP3/FOXK2/CREB3L1/TBX2/PRDM5/JARID2/NR2F6/IKZF5/BTG2/TBX15/ZNF281/REST/TBX22/MSX1/EMX2/GZF1/BATF3/ZNF174/E2F8/SOX6/KLF16/HOXD9/NFATC3/THAP1	51
MF	GO:0042974	retinoic acid receptor binding	10/2481	26/17697	0.001785	0.05529	0.04983	PPARG/TACC1/FUS/PRAME/NSD1/NR4A2/NCOA6/NR1H4/CNOT1/NCOA1	10
MF	GO:0030021	extracellular matrix structural constituent conferring compression resistance	9/2481	22/17697	0.001821	0.05529	0.04983	BGN/PRG4/HAPLN1/ASPN/DCN/ACAN/OGN/FMOD/PRELP	9
MF	GO:0031625	ubiquitin protein ligase binding	59/2481	290/17697	0.001824	0.05529	0.04983	CLU/RRAGA/GABARAPL2/UBXN7/MAP1LC3A/BAG4/NFKBIA/APC/SLC25A5/PRKAR2A/SQSTM1/SMAD7/JUN/BCL10/DNAJA1/STX8/PINK1/MOAP1/TRAF4/UBA52/FBXW7/ERLIN1/HSP90AA1/UBXN1/USP7/TRAF6/EGFR/JAK1/DERL1/ERLIN2/UCHL1/PML/RELA/YWHAZ/VCP/MID1/FANCL/TNFRSF14/LAPTM4B/DIO2/CAMLG/PSMD1/FZD5/UBC/UBE2D3/RANGAP1/ARIH1/HSP90AB1/LYN/FZD4/PCBP2/WFS1/HSPA5/PRKAR2B/PER1/HSPA9/SYT11/CUL1/RNF8	59
MF	GO:0048407	platelet-derived growth factor binding	6/2481	11/17697	0.00185	0.05529	0.04983	COL6A1/COL4A1/PDGFRA/PDGFRB/COL5A1/COL1A2	6
MF	GO:0030674	protein binding, bridging	38/2481	170/17697	0.002092	0.06089	0.05488	RBM14/GRB10/SPSB1/CRADD/SH2B3/ARHGAP6/TRIM6/CAV2/CRKL/FRMD4A/FKBP4/HERPUD1/GAS6/GRB14/FBXW7/NEFH/DAB2/AP2A2/OBSL1/CHN2/MLPH/ITSN2/FLRT2/CHN1/ANK1/COL14A1/FRS2/HCFC1/NUFIP1/KHDRBS1/SORBS1/ANK2/VAV3/TP53BP2/CAV1/SH2D3C/SPSB2/COL1A2	38
MF	GO:0004721	phosphoprotein phosphatase activity	40/2481	182/17697	0.002257	0.06401	0.05769	PPTC7/PTP4A2/DUSP28/CAMK2G/PTPRO/PTPN13/PTP4A1/PPM1J/DLG1/DUSP10/PPP2CA/SSH1/PPM1D/PTP4A3/PTPRH/PPEF2/CTDSPL/PTPN21/MTMR14/PTPRF/PDP1/PPM1A/MTM1/PTPRG/PPP3CB/PTPN14/PPM1F/RNGTT/DUSP1/DUSP18/PPEF1/MTMR7/STYXL1/PPP1R3C/MTMR4/PTPRC/CDKN3/SSH3/PPM1N/PTPRB	40
MF	GO:0043394	proteoglycan binding	12/2481	36/17697	0.002675	0.0727	0.06553	CFH/LPL/AGRN/FN1/PTN/PTPRF/COL5A1/GPNMB/SLIT2/ITGA2/TNC/PTPRC	12
MF	GO:0033613	activating transcription factor binding	22/2481	85/17697	0.002695	0.0727	0.06553	IFI27/PPARG/MEF2D/EP300/TBX5/BHLHE41/JUN/LDB1/BHLHE40/CREB1/CREBBP/ZBTB7A/FOS/RELA/HCFC1/TBX2/YAP1/TBX15/TBX22/TBX1/WFS1/SIN3A	22
MF	GO:0034212	peptide N-acetyltransferase activity	20/2481	75/17697	0.00283	0.07453	0.06717	PHF20/NCOA3/POLE3/EP300/TAF10/HAT1/NAA16/ING3/NAA30/WDR5/CREBBP/GTF3C4/RSF1/HCFC1/MCM3AP/NAA25/TAF1/EPC1/NAA15/NCOA1	20
MF	GO:0051427	hormone receptor binding	40/2481	185/17697	0.003075	0.07771	0.07004	TRIP6/ARID1A/GRIP1/NCOA3/JUND/FHL2/PPARG/EP300/RNF6/TACC1/PRKCB/KDM5D/TAF10/FKBP4/PHB2/FUS/PPID/MED13/ZBTB7A/SIRT1/JUP/TRIM24/JAK1/DDX54/TGFB1I1/PRAME/MED30/NSD1/JMJD1C/NCOA2/NR4A2/ADCYAP1/SLC30A9/TACC2/TAF1/RERG/NCOA6/NR1H4/CNOT1/NCOA1	40
MF	GO:0005085	guanyl-nucleotide exchange factor activity	45/2481	214/17697	0.003122	0.07771	0.07004	EPS8/SEC61B/SH3BP5L/HERC1/TBC1D10A/TAGAP/RGL1/ARHGEF37/ARFGEF2/RAB3IL1/PSD3/AKAP13/FLCN/P2RY12/RAB3GAP2/RAPGEF3/ARHGEF7/FGD5/VAV1/SMCR8/PLEKHG5/EGF/ITSN2/BCAR3/DENND2A/RGL3/RIN3/FARP1/RAPGEF5/ARHGEF16/DENND4B/VAV3/FGD3/SOS2/MADD/SH2D3C/MYCBP2/ARHGEF12/DOCK11/ARHGEF15/DOCK8/RAPGEF4/FBXO8/EIF2B2/EPS8L1	45
MF	GO:0004842	ubiquitin-protein transferase activity	73/2481	382/17697	0.00326	0.07771	0.07004	MYLIP/TNFAIP3/UBE2QL1/MED10/HERC1/CNOT4/MSL2/RNF6/BCOR/TRIM6/FEM1A/TRIM58/KLHL20/TRIM21/ARIH2/RMND5A/ITCH/MED7/FBXW8/TRIM47/UBR7/FBXO4/RNF213/RNF183/TRAF6/TRIM24/HERC3/RNF138/UBE2S/RNF182/HECW2/UBR4/UBE4B/RNF150/CBL/NEURL2/UBE3C/RCHY1/MED30/FBXL13/FBXL8/FANCL/RNF216/TRIM2/RLIM/LRSAM1/DTX3L/UBE2C/PDZRN3/HECTD1/NEURL1B/SKP2/UBE2D3/RNF125/FBXO25/FBXL14/UBE2G2/RNF139/RNF19B/CHFR/RNF103/ARIH1/TNFAIP1/KCMF1/TAF1/MYCBP2/RNF220/RC3H1/BARD1/MAGEL2/ZFP91/RNF8/FBXW2	73
MF	GO:0031994	insulin-like growth factor I binding	6/2481	12/17697	0.003262	0.07771	0.07004	ITGB3/IGFBP2/IGF1R/IGFBP4/IGFBP5/IGFBP3	6
MF	GO:0003714	transcription corepressor activity	49/2481	238/17697	0.003302	0.07771	0.07004	SPEN/MIER3/YY1/HEYL/SCAI/BCOR/GON4L/BHLHE41/CBX4/SFMBT2/LDB1/ELANE/BHLHE40/CCND1/LMCD1/NANOG/CREBBP/HSF4/PARP9/THRB/ZBTB7A/SIRT1/DDIT3/WWTR1/YAF2/MEIS2/TDP2/CBFA2T3/HOXC6/MTA1/DDX54/NR2F2/ZNF136/POU4F1/RLIM/NSD1/YAP1/ZFPM2/ZNF281/RUNX1T1/CNOT7/RCOR3/BATF3/EZH1/SIN3B/E2F8/JUNB/NR1H4/SIN3A	49
MF	GO:0005520	insulin-like growth factor binding	10/2481	28/17697	0.003383	0.07793	0.07024	ITGB3/HTRA4/HTRA1/IGFBP2/IGF1R/HTRA3/KAZALD1/IGFBP4/IGFBP5/IGFBP3	10
MF	GO:0002039	p53 binding	18/2481	66/17697	0.003457	0.07793	0.07024	MUC1/EP300/GATA1/USP10/CREBBP/USP7/SIRT1/TRIM24/TAF3/RCHY1/PLK3/BANP/RNF125/MSX1/TP53BP2/MAPKAPK5/TRIAP1/TAF1	18
MF	GO:0035258	steroid hormone receptor binding	23/2481	92/17697	0.003523	0.07793	0.07024	GRIP1/NCOA3/FHL2/PPARG/EP300/RNF6/TACC1/PRKCB/KDM5D/TAF10/FKBP4/PHB2/FUS/PPID/ZBTB7A/DDX54/TGFB1I1/NSD1/NR4A2/RERG/NCOA6/CNOT1/NCOA1	23
MF	GO:0015295	solute:proton symporter activity	9/2481	24/17697	0.003681	0.07983	0.07195	SLC15A4/SLC25A3/SLC2A8/SLC45A1/SLC2A6/SLC32A1/SLC2A10/SLC2A12/SLC17A5	9
MF	GO:0005088	Ras guanyl-nucleotide exchange factor activity	31/2481	137/17697	0.004216	0.08967	0.08082	EPS8/SH3BP5L/RGL1/ARHGEF37/RAB3IL1/AKAP13/RAB3GAP2/RAPGEF3/ARHGEF7/FGD5/VAV1/SMCR8/PLEKHG5/EGF/ITSN2/DENND2A/RGL3/RIN3/FARP1/RAPGEF5/ARHGEF16/DENND4B/VAV3/FGD3/SOS2/MADD/ARHGEF12/DOCK11/ARHGEF15/RAPGEF4/EPS8L1	31
MF	GO:0016504	peptidase activator activity	12/2481	38/17697	0.004424	0.09112	0.08213	PSMD14/RPS27L/PCOLCE2/PINK1/FN1/SFRP2/PCOLCE/VCP/NLRP1/FBLN1/CAV1/PSME1	12
MF	GO:0033218	amide binding	68/2481	356/17697	0.004449	0.09112	0.08213	CLU/C1QA/CD1C/ACVR1/GNMT/MME/HLA-DPB1/TMEM158/EDNRB/PPIL6/TOMM20/PPARG/INHBA/PPIL1/CLIP3/NFKBIA/VIPR1/TGFB2/PLEKHA3/PHB2/SORL1/C2CD2L/FCGR2B/PPID/NOLC1/IGF1R/CD1B/MSR1/KPNA1/CALCRL/GRIA3/GLP2R/MCHR1/NKTR/NUP153/PTH1R/RAMP2/PPIC/KPNA3/HLA-B/SLC7A9/NUP214/RAMP3/IDE/LAPTM4B/CD300LF/RXFP2/TREM2/GLTP/KDELR3/ACBD5/FZD5/OXTR/IPO5/HSP90AB1/PANK1/PGRMC1/GHR/ITGA2/FZD4/MMACHC/PLTP/ENPEP/CRYAB/EPHB2/SRP54/HLA-A/HMGCL	68
MF	GO:0001102	RNA polymerase II activating transcription factor binding	15/2481	53/17697	0.005004	0.09901	0.08924	IFI27/EP300/TBX5/BHLHE41/JUN/LDB1/BHLHE40/CREB1/CREBBP/FOS/TBX2/TBX15/TBX22/TBX1/SIN3A	15
MF	GO:0060090	molecular adaptor activity	48/2481	237/17697	0.005017	0.09901	0.08924	RBM14/GRB10/EPS8/SPSB1/CRADD/SH2B3/SLC9A3R1/ARHGAP6/PEF1/OTUD4/TRIM6/CAV2/DLG1/CRKL/FRMD4A/FKBP4/HERPUD1/AKAP13/GAS6/GRB14/FBXW7/NEFH/TELO2/DAB2/AP2A2/OBSL1/CHN2/MLPH/ITSN2/FLRT2/CHN1/ANK1/COL14A1/FRS2/HCFC1/AFAP1L2/NUFIP1/KHDRBS1/SORBS1/MPP7/ANK2/VAV3/TP53BP2/CAV1/SH2D3C/CNOT1/SPSB2/COL1A2	48
MF	GO:0004725	protein tyrosine phosphatase activity	24/2481	100/17697	0.005103	0.09901	0.08924	PTP4A2/DUSP28/PTPRO/PTPN13/PTP4A1/DUSP10/SSH1/PTP4A3/PTPRH/PTPN21/MTMR14/PTPRF/MTM1/PTPRG/PTPN14/RNGTT/DUSP1/DUSP18/MTMR7/MTMR4/PTPRC/CDKN3/SSH3/PTPRB	24
MF	GO:0097617	annealing activity	6/2481	13/17697	0.005344	0.09917	0.08939	EIF4B/FXR1/ZRANB3/EIF4H/RECQL4/SMARCA1	6
MF	GO:0019199	transmembrane receptor protein kinase activity	20/2481	79/17697	0.005375	0.09917	0.08939	LTBP1/ACVR1/FLT1/NRP1/IGF1R/EGFR/NTRK2/ACVR2A/EPHB4/PDGFRA/PDGFRB/TIE1/TEK/PDGFRL/EFEMP1/DDR2/KDR/LTBP4/EPHB2/AXL	20
MF	GO:0019955	cytokine binding	29/2481	128/17697	0.005415	0.09917	0.08939	ITGB3/LTBP1/ACVR1/ITGA4/CD109/IL1R1/ELANE/KLHL20/ZFP36/PXDN/NRP1/CRLF1/TWSG1/CXCR1/IL23R/PDPN/TNFRSF11A/IL13RA2/OSMR/IL12A/LIFR/GREM2/TNFRSF14/IL10RA/GHR/FZD4/A2M/LTBP4/NLRP7	29
MF	GO:0017049	GTP-Rho binding	8/2481	21/17697	0.00547	0.09917	0.08939	RTKN/ANLN/WHAMM/PKN3/PKN2/TNFAIP1/CDC42EP5/STXBP6	8
MF	GO:0042813	Wnt-activated receptor activity	7/2481	17/17697	0.005652	0.1008	0.09087	LRP5L/EGF/FZD10/FZD5/ROR1/FZD4/LRP5	7
MF	GO:0015026	coreceptor activity	13/2481	44/17697	0.005864	0.1022	0.09214	ITGB3/ITGA4/RGMA/LILRA4/NRP1/GPC4/ACVR2A/RAMP2/GPC6/RAMP3/ROR1/GPR15/LRP5	13
MF	GO:0008135	translation factor activity, RNA binding	21/2481	85/17697	0.005963	0.1022	0.09214	EIF5/TSFM/EIF5A/EIF3L/EIF1AY/EIF4B/DENR/EIF2S1/EIF1/EIF2A/EIF4H/EIF3F/EEF1A1/CPEB1/EIF3K/EIF3M/EIF4A1/EIF2B2/GFM2/ABCF1/CPEB2	21
MF	GO:0017046	peptide hormone binding	14/2481	49/17697	0.006008	0.1022	0.09214	ACVR1/EDNRB/INHBA/VIPR1/C2CD2L/IGF1R/CALCRL/GLP2R/PTH1R/RAMP2/IDE/RXFP2/OXTR/GHR	14
MF	GO:0042277	peptide binding	57/2481	295/17697	0.006793	0.1127	0.1016	CLU/C1QA/CD1C/ACVR1/MME/HLA-DPB1/TMEM158/EDNRB/PPIL6/TOMM20/PPARG/INHBA/PPIL1/NFKBIA/VIPR1/TGFB2/SORL1/C2CD2L/FCGR2B/PPID/NOLC1/IGF1R/CD1B/MSR1/KPNA1/CALCRL/GRIA3/GLP2R/MCHR1/NKTR/NUP153/PTH1R/RAMP2/PPIC/KPNA3/HLA-B/SLC7A9/NUP214/RAMP3/IDE/RXFP2/TREM2/KDELR3/FZD5/OXTR/IPO5/HSP90AB1/PGRMC1/GHR/ITGA2/FZD4/MMACHC/ENPEP/CRYAB/EPHB2/SRP54/HLA-A	57
MF	GO:0060589	nucleoside-triphosphatase regulator activity	65/2481	344/17697	0.006827	0.1127	0.1016	ARHGAP18/RABGAP1L/EIF5/ARHGAP6/TBC1D10A/RTKN/TAGAP/DEPDC5/ASAP2/JUN/DNAJA1/ATP1B2/SRGAP1/RAP1GAP2/RGS7/ARHGAP10/NRP1/ASAP3/IPO7/FLCN/RAB3GAP2/RALGAPB/ARHGAP9/NUP50/RASAL2/RGS6/DNAJC10/SESN2/RUNDC3A/CHN2/DEPDC1/GRPEL1/ARHGAP32/PLCB1/ARHGAP19/CHN1/DNAJC24/TBC1D16/ARHGAP28/RIN3/ARHGAP29/THY1/CHML/RANGAP1/VAV3/IPO5/ARFGAP2/ARHGAP30/TBC1D2B/SLIT2/ACAP2/DNAJA2/DLC1/ARHGAP11A/RGS14/GIT2/TBC1D9/GPSM1/PFN1/ARHGEF12/RALGAPA2/RGS17/ARHGEF15/CPEB2/GDI1	65
MF	GO:0019787	ubiquitin-like protein transferase activity	75/2481	407/17697	0.0073	0.1187	0.107	MYLIP/TNFAIP3/UBE2QL1/MED10/HERC1/CNOT4/MSL2/RNF6/BCOR/TRIM6/FEM1A/TRIM58/CBX4/KLHL20/TRIM21/ARIH2/RMND5A/ITCH/MED7/FBXW8/TRIM47/UBR7/FBXO4/RNF213/RNF183/TRAF6/TRIM24/HERC3/RNF138/UBE2S/RNF182/HECW2/UBR4/UBE4B/RNF150/CBL/NEURL2/UBE3C/UBL4A/RCHY1/MED30/FBXL13/FBXL8/FANCL/RNF216/TRIM2/RLIM/LRSAM1/DTX3L/UBE2C/PDZRN3/HECTD1/NEURL1B/SKP2/UBE2D3/RNF125/FBXO25/FBXL14/UBE2G2/RNF139/RNF19B/CHFR/RNF103/ARIH1/TNFAIP1/KCMF1/TAF1/MYCBP2/RNF220/RC3H1/BARD1/MAGEL2/ZFP91/RNF8/FBXW2	75
MF	GO:0017022	myosin binding	18/2481	71/17697	0.007897	0.1266	0.1141	MYL9/IQGAP3/SLC9A3R1/TRAK1/MYL4/ARFGEF2/FUS/SHROOM4/CALD1/MLPH/RAB6B/DMD/RAB8A/GIPC1/CORO1A/LIMCH1/AXL/LARP6	18
MF	GO:0097001	ceramide binding	6/2481	14/17697	0.008255	0.1296	0.1168	CLIP3/PLEKHA3/LAPTM4B/CD300LF/GLTP/PLTP	6
MF	GO:0030695	GTPase regulator activity	58/2481	304/17697	0.00832	0.1296	0.1168	ARHGAP18/RABGAP1L/EIF5/ARHGAP6/TBC1D10A/RTKN/TAGAP/DEPDC5/ASAP2/JUN/SRGAP1/RAP1GAP2/RGS7/ARHGAP10/NRP1/ASAP3/IPO7/FLCN/RAB3GAP2/RALGAPB/ARHGAP9/NUP50/RASAL2/RGS6/SESN2/RUNDC3A/CHN2/DEPDC1/ARHGAP32/PLCB1/ARHGAP19/CHN1/TBC1D16/ARHGAP28/RIN3/ARHGAP29/THY1/CHML/RANGAP1/VAV3/IPO5/ARFGAP2/ARHGAP30/TBC1D2B/SLIT2/ACAP2/DLC1/ARHGAP11A/RGS14/GIT2/TBC1D9/GPSM1/ARHGEF12/RALGAPA2/RGS17/ARHGEF15/CPEB2/GDI1	58
MF	GO:0003743	translation initiation factor activity	14/2481	51/17697	0.008781	0.1349	0.1216	EIF5/EIF3L/EIF1AY/EIF4B/DENR/EIF2S1/EIF1/EIF2A/EIF4H/EIF3F/EIF3K/EIF3M/EIF4A1/EIF2B2	14
MF	GO:0016407	acetyltransferase activity	25/2481	110/17697	0.00897	0.1359	0.1225	PHF20/NCOA3/POLE3/EP300/TAF10/HAT1/NAA16/ING3/NAA30/WDR5/CREBBP/GTF3C4/LPCAT4/ACAT2/GCAT/RSF1/HCFC1/MCM3AP/NAA25/CRAT/TAF1/EPC1/NAA15/LPCAT1/NCOA1	25
MF	GO:0003779	actin binding	78/2481	431/17697	0.009862	0.1456	0.1312	ENC1/ABLIM3/CTTN/EPS8/TNS1/AIF1L/TMOD1/MARCKSL1/WASF3/WASF2/SNCA/MYL4/SSH1/TPM1/KLHL20/DAAM2/ANLN/PHACTR4/FMNL1/CTNNAL1/NEXN/SHROOM4/DIAPH1/CALD1/EGFR/NOS3/AVIL/OBSL1/MTSS1/LDB3/COTL1/MSN/MLPH/VASH1/UTRN/CEACAM1/PFN4/FERMT2/LMOD1/TMEM201/PLEKHH2/WHAMM/ACTN1/WASF1/KCNMA1/ENAH/MYO1C/CAPZA1/RCSD1/TMSB4Y/MYH9/FLNC/SMTN/SORBS1/CDK5R1/DIAPH3/TMSB15A/FBXO25/FAM107A/FLNA/ARPC2/PDLIM4/HCLS1/MYH10/DMD/EPB41L1/PFN1/FHDC1/SSH3/GIPC1/CORO1A/PARVA/LSP1/LIMCH1/MYO5C/SHANK3/EPS8L1/MYO15A	78
MF	GO:0004714	transmembrane receptor protein tyrosine kinase activity	16/2481	62/17697	0.009954	0.1456	0.1312	FLT1/NRP1/IGF1R/EGFR/NTRK2/EPHB4/PDGFRA/PDGFRB/TIE1/TEK/PDGFRL/EFEMP1/DDR2/KDR/EPHB2/AXL	16
MF	GO:0042826	histone deacetylase binding	25/2481	111/17697	0.01008	0.1456	0.1312	SIRT2/MIER3/BEX4/MEF2D/BCOR/AKAP8L/NIPBL/BHLHE41/SFPQ/TAL1/HES1/BRMS1L/CCND1/HSP90AA1/TRAF6/RELA/MTA1/HOXA10/KLF4/GLI3/PKN2/SUDS3/WDTC1/HSP90AB1/AKAP8	25
MF	GO:0030159	receptor signaling complex scaffold activity	8/2481	23/17697	0.01018	0.1456	0.1312	GRIP1/DEDD2/GRIP2/G3BP2/CARD10/MAGI2/RGS14/SHANK3	8
MF	GO:0043022	ribosome binding	15/2481	57/17697	0.01027	0.1456	0.1312	OLA1/EIF5A/PELO/NAA16/EIF2S1/ZC3H12A/YTHDF1/EIF2A/CPEB1/YTHDF3/EIF3K/MTOR/HSPA5/NAA15/CPEB2	15
MF	GO:0030331	estrogen receptor binding	12/2481	42/17697	0.01059	0.1483	0.1336	PPARG/TACC1/TAF10/PHB2/FUS/PPID/DDX54/NSD1/RERG/NCOA6/CNOT1/NCOA1	12
MF	GO:0003727	single-stranded RNA binding	22/2481	95/17697	0.01096	0.1516	0.1366	PABPC4/EIF4B/FXR1/DHX9/CBX4/RBM7/RBM3/PABPC3/ILF3/DDX11/IFIH1/EIF4H/POLR2G/JMJD6/IFIT5/RBPMS/KHDRBS1/PABPC4L/RBMX/RBMS3/RPS7/POLR2D	22
MF	GO:0005402	carbohydrate:cation symporter activity	7/2481	19/17697	0.01136	0.1551	0.1398	SLC2A8/SLC45A1/SLC2A6/SLC2A10/SLC2A12/SLC23A1/SLC17A5	7
MF	GO:0005092	GDP-dissociation inhibitor activity	6/2481	15/17697	0.01215	0.1619	0.1459	EIF5/SESN2/CHML/RGS14/GPSM1/GDI1	6
MF	GO:0005161	platelet-derived growth factor receptor binding	6/2481	15/17697	0.01215	0.1619	0.1459	ITGB3/IL1R1/ERN1/PDGFRA/PDGFRB/LYN	6
MF	GO:0097718	disordered domain specific binding	10/2481	33/17697	0.01235	0.1626	0.1466	NCOA3/KEAP1/PPIL1/GJA5/HSP90AA1/FN1/AP2A2/KCNA1/FKBP8/HSP90AB1	10
MF	GO:0004402	histone acetyltransferase activity	16/2481	64/17697	0.01356	0.1765	0.1591	PHF20/NCOA3/POLE3/EP300/TAF10/HAT1/ING3/WDR5/CREBBP/GTF3C4/RSF1/HCFC1/MCM3AP/TAF1/EPC1/NCOA1	16
MF	GO:0003725	double-stranded RNA binding	18/2481	75/17697	0.01407	0.1809	0.163	YRDC/MBNL1/STAU2/EIF4B/FXR1/DHX9/MRPL44/ADARB1/DDX21/ILF3/IFIH1/EIF4H/MSN/ACTN1/HSP90AB1/RC3H1/STAU1/EIF4A1	18
MF	GO:0032947	protein-containing complex scaffold activity	9/2481	29/17697	0.0147	0.1847	0.1665	GRIP1/DEDD2/AKAP13/GRIP2/G3BP2/CARD10/MAGI2/RGS14/SHANK3	9
MF	GO:0046966	thyroid hormone receptor binding	9/2481	29/17697	0.0147	0.1847	0.1665	TRIP6/NCOA3/TACC1/FUS/MED13/MED30/NSD1/JMJD1C/NCOA6	9
MF	GO:0019211	phosphatase activator activity	6/2481	16/17697	0.01717	0.211	0.1902	PPP1R15A/PHACTR4/BMP2/PPP2R5E/FRS2/IGFBP3	6
MF	GO:0032183	SUMO binding	6/2481	16/17697	0.01717	0.211	0.1902	TDG/CBX4/USPL1/PML/SOBP/NR3C1	6
MF	GO:0043177	organic acid binding	40/2481	205/17697	0.01776	0.2134	0.1923	HBB/ALAS2/HBD/LCN12/DDAH1/GNMT/PPARG/PLOD2/FABP5/SLC1A3/AGRN/SELP/CYP26B1/THNSL2/HBM/PAM/APOC1/GPR143/SESN2/NOS3/ASS1/SLC1A1/PRR7/AKR1C2/NR2F2/SESN3/CRABP1/CYP27C1/HBQ1/HAPLN1/CPS1/LYVE1/STARD5/RYR2/ACAN/HMGCS1/GLRB/NR1H4/FABP3/HMGCL	40
MF	GO:0061733	peptide-lysine-N-acetyltransferase activity	16/2481	66/17697	0.01812	0.2134	0.1923	PHF20/NCOA3/POLE3/EP300/TAF10/HAT1/ING3/WDR5/CREBBP/GTF3C4/RSF1/HCFC1/MCM3AP/TAF1/EPC1/NCOA1	16
MF	GO:0016004	phospholipase activator activity	5/2481	12/17697	0.01814	0.2134	0.1923	ARHGAP6/PDPK1/ARF1/STX4/CCL8	5
MF	GO:0032036	myosin heavy chain binding	5/2481	12/17697	0.01814	0.2134	0.1923	MYL9/MYL4/CORO1A/LIMCH1/AXL	5
MF	GO:0008138	protein tyrosine/serine/threonine phosphatase activity	12/2481	45/17697	0.01849	0.2153	0.194	DUSP28/PTP4A1/DUSP10/SSH1/PTP4A3/PPM1F/RNGTT/DUSP1/DUSP18/STYXL1/CDKN3/SSH3	12
MF	GO:0051219	phosphoprotein binding	19/2481	83/17697	0.0194	0.2235	0.2014	RRAGA/SHF/SNCA/CRKL/CBX4/FKBP4/FBXW7/SHD/VAV1/TBL2/CBL/LRP11/PLAT/MID1/PRKCSH/MTOR/LYN/SHE/PIN1	19
MF	GO:0051861	glycolipid binding	7/2481	21/17697	0.02037	0.2322	0.2093	CD1C/CLIP3/SELP/IL2/THY1/GLTP/LYN	7
MF	GO:0030374	nuclear receptor transcription coactivator activity	16/2481	67/17697	0.0208	0.2347	0.2115	RBM14/NCOA3/PPARG/PRKCB/DCAF6/PPRC1/THRB/MED13/NR1D2/MED30/ACTN1/NCOA2/SLC30A9/NCOA6/NR1H4/NCOA1	16
MF	GO:0005496	steroid binding	21/2481	95/17697	0.02117	0.2365	0.2132	OSBP/GRAMD1B/OSBPL6/OSBP2/APOF/ERLIN1/CYP21A2/HSD11B2/ERLIN2/OSBPL9/HSD11B1/PAQR6/HSD17B1/NR3C1/STARD5/AKR1D1/CAV1/PGRMC1/GRAMD1C/KL/NR1H4	21
MF	GO:0003713	transcription coactivator activity	58/2481	319/17697	0.02144	0.2371	0.2137	RBM14/ARID1A/SERTAD2/GRIP1/NCOA3/JUND/ARID1B/FHL2/NFKBIB/PPARG/YY1/EP300/NFKB2/PRKCB/TAF4/JUN/DCAF6/BCL10/DHX9/RXRB/FUS/MED7/CREBBP/SMARCC1/PPRC1/THRB/MED13/FOXC1/NFATC4/MAX/WWTR1/JUP/TRIM24/YAF2/PQBP1/PML/MED6/MTA1/JMJD6/TGFB1I1/NR1D2/MED30/ACTN1/PRRX1/POU4F1/HCFC1/NUPR1/YAP1/RBPMS/ZFPM2/PSMD9/NCOA2/SLC30A9/TAF1/JUNB/NCOA6/NR1H4/NCOA1	58
MF	GO:0051019	mitogen-activated protein kinase binding	8/2481	26/17697	0.0221	0.242	0.2181	DUSP10/PPM1D/ACE/TNIP1/SIRT1/GCH1/DUSP1/MAPKAPK5	8
MF	GO:0003755	peptidyl-prolyl cis-trans isomerase activity	11/2481	41/17697	0.02257	0.2424	0.2185	PPIL6/PPIL1/FKBP4/PPID/FKBP10/NKTR/PPIC/FKBP1B/FKBP8/PIN4/PIN1	11
MF	GO:0008080	N-acetyltransferase activity	20/2481	90/17697	0.02282	0.2424	0.2185	PHF20/NCOA3/POLE3/EP300/TAF10/HAT1/NAA16/ING3/NAA30/WDR5/CREBBP/GTF3C4/RSF1/HCFC1/MCM3AP/NAA25/TAF1/EPC1/NAA15/NCOA1	20
MF	GO:0004724	magnesium-dependent protein serine/threonine phosphatase activity	6/2481	17/17697	0.02345	0.2424	0.2185	PPM1J/PPM1D/PDP1/PPM1A/PPM1F/PPM1N	6
MF	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	6/2481	17/17697	0.02345	0.2424	0.2185	PTPRO/PTPRH/PTPRF/PTPRG/PTPRC/PTPRB	6
MF	GO:0019198	transmembrane receptor protein phosphatase activity	6/2481	17/17697	0.02345	0.2424	0.2185	PTPRO/PTPRH/PTPRF/PTPRG/PTPRC/PTPRB	6
MF	GO:0043024	ribosomal small subunit binding	6/2481	17/17697	0.02345	0.2424	0.2185	EIF4B/LARP1/EIF1/EIF4H/ABCE1/CPEB2	6
MF	GO:0042562	hormone binding	22/2481	102/17697	0.02432	0.2468	0.2224	ACVR1/SEC61B/EDNRB/INHBA/VIPR1/C2CD2L/IGF1R/THRB/CALCRL/EGFR/GLP2R/MCHR1/ADIPOR2/PTH1R/RAMP2/HSD17B1/IDE/ALDH1A3/RXFP2/NR3C1/OXTR/GHR	22
MF	GO:0051087	chaperone binding	22/2481	102/17697	0.02432	0.2468	0.2224	CLU/DNLZ/BAG4/SDF2L1/DNAJA1/TIMM44/TIMM10/HYOU1/VWF/HES1/ERP29/FN1/DNAJC10/PDPN/GRPEL1/UBL4A/DNAJA4/CP/HSPB6/DNAJA2/BAK1/HSPA5	22
MF	GO:0005070	SH3/SH2 adaptor activity	13/2481	52/17697	0.02461	0.2475	0.2231	GRB10/SH2B3/ARHGAP6/CRKL/GRB14/CHN2/ITSN2/CHN1/KHDRBS1/SORBS1/VAV3/TP53BP2/SH2D3C	13
MF	GO:0031005	filamin binding	5/2481	13/17697	0.02613	0.2568	0.2315	FBLIM1/CRMP1/CEACAM1/DPYSL3/TMEM67	5
MF	GO:0043495	protein membrane anchor	5/2481	13/17697	0.02613	0.2568	0.2315	SLC4A1/LPL/NUP153/MYH9/SUN2	5
MF	GO:0005158	insulin receptor binding	7/2481	22/17697	0.02635	0.2568	0.2315	GRB10/PDPK1/LMBRD1/IGF1R/IGF1/IRS2/SORBS1	7
MF	GO:0035591	signaling adaptor activity	18/2481	80/17697	0.02647	0.2568	0.2315	GRB10/EPS8/SH2B3/ARHGAP6/CRKL/AKAP13/GRB14/CHN2/ITSN2/CHN1/FRS2/AFAP1L2/KHDRBS1/SORBS1/MPP7/VAV3/TP53BP2/SH2D3C	18
MF	GO:0030291	protein serine/threonine kinase inhibitor activity	9/2481	32/17697	0.02794	0.2664	0.2401	SPRY2/PRKAR2A/CDKN1C/CDKN2C/HSPB1/PKIB/PRKAG2/CDKN2B/PRKAR2B	9
MF	GO:0031369	translation initiation factor binding	9/2481	32/17697	0.02794	0.2664	0.2401	EIF5/LARP1/GCH1/EIF3F/TBL2/POLR2G/EIF3M/POLR2D/SYT11	9
MF	GO:0004386	helicase activity	32/2481	163/17697	0.02893	0.2735	0.2465	DDX3Y/DHX57/XRCC6/NAV2/DDX42/DHX9/HELZ/ZRANB3/HELB/CHD1/DDX55/DDX19A/DDX21/DDX11/DDX50/DDX52/IFIH1/DDX10/CDC45/DDX54/RECQL4/DDX60L/EP400/CHD2/CHD5/BTAF1/SMARCA1/EIF4A1/DDX46/DDX6/CHD9/MCM5	32
MF	GO:0004713	protein tyrosine kinase activity	27/2481	134/17697	0.03139	0.2907	0.262	DSTYK/BMX/CLK1/FLT1/HIPK1/NRP1/IGF1R/BTK/EGFR/NTRK2/JAK1/EPHB4/PDGFRA/MELK/CLK3/PDGFRB/TIE1/TEK/PDGFRL/EFEMP1/DDR2/PKDCC/TTK/LYN/KDR/EPHB2/AXL	27
MF	GO:0001221	transcription cofactor binding	11/2481	43/17697	0.03161	0.2907	0.262	TFAM/CDK9/CREB1/FOXC1/ZBTB7A/CCNT2/RELA/SIX1/KLF4/CDC5L/PER1	11
MF	GO:0019207	kinase regulator activity	39/2481	207/17697	0.03174	0.2907	0.262	FAM20A/SOCS7/SPRY2/FGF13/SH3BP5L/CCNL1/APC/PRKAR2A/BCL10/LTF/GHRL/TGFB1/CDKN1C/GAS6/CCND1/RPLP1/CDKN2C/ITPRIP/SMCR8/HSPB1/CCNT2/PKIB/EGF/CCNYL2/STK4/DBF4/CNTD2/CCNY/IL2/KLF4/AFAP1L2/PRKAG2/IBTK/CDKN2B/CDK5R1/WDR91/HSP90AB1/MADD/PRKAR2B	39
MF	GO:0004722	protein serine/threonine phosphatase activity	17/2481	76/17697	0.03207	0.2907	0.262	PPTC7/CAMK2G/PPM1J/PPP2CA/PPM1D/PPEF2/CTDSPL/PDP1/PPM1A/PPP3CB/PPM1F/DUSP1/PPEF1/PPP1R3C/MTMR4/CDKN3/PPM1N	17
MF	GO:0070063	RNA polymerase binding	17/2481	76/17697	0.03207	0.2907	0.262	NCOA3/STOM/SPTY2D1/TAF10/DHX9/ZFP36/RPRD2/NOLC1/CCNT2/PABPN1/WAC/PCF11/GTF2E1/PKN2/PCIF1/ANP32B/TCOF1	17
MF	GO:0140104	molecular carrier activity	13/2481	54/17697	0.03295	0.2962	0.267	HBB/HBD/FXN/IPO9/CYGB/HBM/KPNA1/KPNA3/NUP214/HBQ1/TNPO3/IPO5/KPNA4	13
MF	GO:0001223	transcription coactivator binding	7/2481	23/17697	0.03342	0.2969	0.2676	TFAM/CDK9/CREB1/FOXC1/CCNT2/RELA/SIX1	7
MF	GO:0003785	actin monomer binding	8/2481	28/17697	0.0341	0.2969	0.2676	MYL4/NOS3/MTSS1/PFN4/TMSB4Y/TMSB15A/PFN1/CORO1A	8
MF	GO:0043425	bHLH transcription factor binding	8/2481	28/17697	0.0341	0.2969	0.2676	BHLHE41/TWIST1/BHLHE40/CREBBP/SIRT1/SOX9/KLF5/PSMD9	8
MF	GO:0090079	translation regulator activity, nucleic acid binding	8/2481	28/17697	0.0341	0.2969	0.2676	PAIP2B/RPS27L/LARP1/PAIP2/CELF1/CPEB1/MIF4GD/CPEB2	8
MF	GO:0045182	translation regulator activity	14/2481	60/17697	0.0353	0.3022	0.2723	PAIP2B/RPS27L/EIF2AK4/FXR1/IREB2/RBM3/LARP1/PAIP2/RPL10/CELF1/CPEB1/MIF4GD/MTOR/CPEB2	14
MF	GO:0061630	ubiquitin protein ligase activity	41/2481	221/17697	0.03533	0.3022	0.2723	MYLIP/MED10/MSL2/RNF6/TRIM6/TRIM58/ARIH2/ITCH/MED7/UBR7/FBXO4/RNF183/TRAF6/TRIM24/RNF138/HECW2/UBE4B/RNF150/CBL/NEURL2/MED30/FBXL8/FANCL/RNF216/TRIM2/RLIM/LRSAM1/PDZRN3/NEURL1B/SKP2/RNF125/RNF139/RNF19B/CHFR/RNF103/ARIH1/KCMF1/MYCBP2/RNF220/RC3H1/RNF8	41
MF	GO:0005344	oxygen carrier activity	5/2481	14/17697	0.03606	0.3022	0.2723	HBB/HBD/CYGB/HBM/HBQ1	5
MF	GO:0060229	lipase activator activity	5/2481	14/17697	0.03606	0.3022	0.2723	ARHGAP6/PDPK1/ARF1/STX4/CCL8	5
MF	GO:0070403	NAD+ binding	5/2481	14/17697	0.03606	0.3022	0.2723	SIRT2/HPGD/SIRT1/ALDH1A3/SIRT7	5
MF	GO:0042578	phosphoric ester hydrolase activity	64/2481	367/17697	0.03639	0.3026	0.2728	PLD4/PPTC7/PTP4A2/DUSP28/INPP5D/CAMK2G/PTPRO/PTPN13/PRKAR2A/PTP4A1/PPM1J/DLG1/DUSP10/PPP2CA/SSH1/PDIA3/PFKFB2/PPM1D/PTP4A3/PDE2A/SAMHD1/PTPRH/PPEF2/CTDSPL/SMPD3/ALPL/PDE4B/BDKRB2/TDP2/NT5DC3/PLCB2/PTPN21/PLCB1/MTMR14/PTPRF/GDPD1/PDP1/PPM1A/MTM1/ACP5/PLCD4/PTPRG/PDE1A/PPP3CB/PTPN14/ENPP2/PPM1F/RNGTT/DUSP1/INPP5F/DUSP18/PPEF1/PDE6G/MTMR7/STYXL1/PPP1R3C/PRKAR2B/MTMR4/APEX2/PTPRC/CDKN3/SSH3/PPM1N/PTPRB	64
MF	GO:0050681	androgen receptor binding	11/2481	44/17697	0.03699	0.3053	0.2751	GRIP1/NCOA3/FHL2/EP300/RNF6/PRKCB/KDM5D/ZBTB7A/TGFB1I1/NSD1/NCOA1	11
MF	GO:0061980	regulatory RNA binding	10/2481	39/17697	0.03885	0.3077	0.2774	RBM4/DHX9/MATR3/ZC3H12A/DDX21/ZC3H7A/NEAT1/ZC3H10/TLR9/RC3H1	10
MF	GO:0005096	GTPase activator activity	49/2481	273/17697	0.03946	0.3077	0.2774	ARHGAP18/RABGAP1L/ARHGAP6/TBC1D10A/TAGAP/DEPDC5/ASAP2/JUN/SRGAP1/RAP1GAP2/RGS7/ARHGAP10/NRP1/ASAP3/FLCN/RAB3GAP2/RALGAPB/ARHGAP9/NUP50/RASAL2/RGS6/CHN2/DEPDC1/ARHGAP32/PLCB1/ARHGAP19/CHN1/TBC1D16/ARHGAP28/RIN3/ARHGAP29/THY1/CHML/RANGAP1/VAV3/ARFGAP2/ARHGAP30/TBC1D2B/ACAP2/DLC1/ARHGAP11A/RGS14/GIT2/TBC1D9/ARHGEF12/RALGAPA2/RGS17/ARHGEF15/GDI1	49
MF	GO:0004016	adenylate cyclase activity	4/2481	10/17697	0.0401	0.3077	0.2774	ADCY3/ADCY7/ADCY4/ADCY6	4
MF	GO:0004955	prostaglandin receptor activity	4/2481	10/17697	0.0401	0.3077	0.2774	PPARG/HPGD/PTGER4/PTGFR	4
MF	GO:0031720	haptoglobin binding	4/2481	10/17697	0.0401	0.3077	0.2774	HBB/HBD/HBM/HBQ1	4
MF	GO:0035374	chondroitin sulfate binding	4/2481	10/17697	0.0401	0.3077	0.2774	RTN4RL1/AGRN/PTN/DPYSL3	4
MF	GO:0140035	ubiquitination-like modification-dependent protein binding	4/2481	10/17697	0.0401	0.3077	0.2774	ANKRD13D/ANKRD13B/ANKRD13A/IDE	4
MF	GO:0140036	ubiquitin-dependent protein binding	4/2481	10/17697	0.0401	0.3077	0.2774	ANKRD13D/ANKRD13B/ANKRD13A/IDE	4
MF	GO:0001972	retinoic acid binding	6/2481	19/17697	0.04023	0.3077	0.2774	LCN12/FABP5/CYP26B1/NR2F2/CRABP1/CYP27C1	6
MF	GO:0016722	oxidoreductase activity, oxidizing metal ions	6/2481	19/17697	0.04023	0.3077	0.2774	FXN/ETFDH/STEAP2/CP/MMACHC/HEPH	6
MF	GO:0051082	unfolded protein binding	26/2481	131/17697	0.04034	0.3077	0.2774	CLU/PPIL6/TOMM20/HSP90B1/DNAJA1/CHAF1A/AHSP/HEATR3/ERN1/PPID/HSP90AA1/SERPINH1/NKTR/GRPEL1/PPIC/DNAJA4/CCT8/HSPB6/SPG7/HSP90AB1/DNAJA2/PFDN1/TMEM67/HSPA5/CRYAB/HSPA9	26
MF	GO:0019887	protein kinase regulator activity	34/2481	180/17697	0.04123	0.3123	0.2815	FAM20A/SPRY2/FGF13/SH3BP5L/CCNL1/APC/PRKAR2A/LTF/GHRL/TGFB1/CDKN1C/GAS6/CCND1/RPLP1/CDKN2C/ITPRIP/SMCR8/HSPB1/CCNT2/PKIB/EGF/CCNYL2/STK4/DBF4/CNTD2/CCNY/AFAP1L2/PRKAG2/IBTK/CDKN2B/CDK5R1/HSP90AB1/MADD/PRKAR2B	34
MF	GO:0016859	cis-trans isomerase activity	11/2481	45/17697	0.04297	0.3202	0.2886	PPIL6/PPIL1/FKBP4/PPID/FKBP10/NKTR/PPIC/FKBP1B/FKBP8/PIN4/PIN1	11
MF	GO:0048156	tau protein binding	11/2481	45/17697	0.04297	0.3202	0.2886	CLU/EP300/SNCA/PPP2CA/FKBP4/HSP90AA1/MAP2/TTBK2/HSP90AB1/MARK1/PIN1	11
MF	GO:0043621	protein self-association	13/2481	56/17697	0.04313	0.3202	0.2886	SLC9A3R1/TNFAIP3/PPARG/AGA/BCL10/TDG/LDB1/ACVR2A/PTH1R/RYR2/TMEM43/RSAD2/SHANK3	13
MF	GO:0005089	Rho guanyl-nucleotide exchange factor activity	17/2481	79/17697	0.04477	0.3301	0.2975	EPS8/ARHGEF37/AKAP13/ARHGEF7/FGD5/VAV1/PLEKHG5/ITSN2/FARP1/ARHGEF16/VAV3/FGD3/SOS2/ARHGEF12/DOCK11/ARHGEF15/EPS8L1	17
MF	GO:0030145	manganese ion binding	14/2481	62/17697	0.04537	0.3323	0.2995	ARG2/ME1/ARG1/GALNT3/PAPOLA/PPEF2/DCP2/MTPAP/TDP2/MGAT2/PPM1A/PPEF1/PPM1N/HMGCL	14
MF	GO:0047485	protein N-terminus binding	22/2481	109/17697	0.0476	0.3383	0.3049	SCFD1/SLC9A3R1/NCOA3/EIF5A/NIPBL/SNCA/SRRM2/SCT/TGFB1/RND2/PHB2/GTF2H3/VWF/STXBP1/SMARCC1/CHMP6/TRAF6/RELA/PDCD10/DCN/DCTN4/NCOA1	22
MF	GO:0016229	steroid dehydrogenase activity	9/2481	35/17697	0.04789	0.3383	0.3049	DHRS9/HSD3B7/HSD11B2/HSD17B14/HSD11B1/HSD17B1/AKR1C2/AKR1D1/HSD17B3	9
MF	GO:0000900	translation repressor activity, mRNA regulatory element binding	5/2481	15/17697	0.04802	0.3383	0.3049	PAIP2B/PAIP2/CELF1/CPEB1/CPEB2	5
MF	GO:0004953	icosanoid receptor activity	5/2481	15/17697	0.04802	0.3383	0.3049	CYSLTR2/PPARG/HPGD/PTGER4/PTGFR	5
MF	GO:0015271	outward rectifier potassium channel activity	5/2481	15/17697	0.04802	0.3383	0.3049	KCND3/KCNA5/KCNMA1/KCNT2/KCNA3	5
MF	GO:0017160	Ral GTPase binding	5/2481	15/17697	0.04802	0.3383	0.3049	RGL1/RGL3/MYO1C/USP33/FLNA	5
MF	GO:0008266	poly(U) RNA binding	8/2481	30/17697	0.04987	0.3469	0.3126	PABPC4/RBM3/PABPC3/IFIT5/KHDRBS1/PABPC4L/RBMS3/RPS7	8
MF	GO:0043548	phosphatidylinositol 3-kinase binding	8/2481	30/17697	0.04987	0.3469	0.3126	PTPN13/IGF1R/CBL/IRS2/PDGFRB/HCST/CORO1A/AXL	8
MF	GO:0019209	kinase activator activity	18/2481	86/17697	0.05054	0.3487	0.3143	FAM20A/SPRY2/FGF13/BCL10/LTF/GHRL/TGFB1/GAS6/RPLP1/CCNT2/EGF/STK4/DBF4/IL2/AFAP1L2/PRKAG2/CDK5R1/MADD	18
MF	GO:0061608	nuclear import signal receptor activity	6/2481	20/17697	0.05087	0.3487	0.3143	IPO9/KPNA1/KPNA3/TNPO3/IPO5/KPNA4	6
MF	GO:0008139	nuclear localization sequence binding	7/2481	25/17697	0.05107	0.3487	0.3143	NFKBIA/NOLC1/KPNA1/NUP153/KPNA3/NUP214/IPO5	7
MF	GO:1990782	protein tyrosine kinase binding	19/2481	93/17697	0.05617	0.3744	0.3374	ACVR1/SH2B3/TRIM6/SQSTM1/GAS6/GRB14/HSP90AA1/PRR7/CBL/CEACAM1/FRS2/NEDD9/TREM2/ANGPT2/ARHGEF16/PTPN14/NOX4/CDH5/MST1	19
MF	GO:0004312	fatty acid synthase activity	4/2481	11/17697	0.05619	0.3744	0.3374	OLAH/OXSM/ELOVL7/ELOVL5	4
MF	GO:0004954	prostanoid receptor activity	4/2481	11/17697	0.05619	0.3744	0.3374	PPARG/HPGD/PTGER4/PTGFR	4
MF	GO:0099186	structural constituent of postsynapse	4/2481	11/17697	0.05619	0.3744	0.3374	DLG1/NEFH/DLG2/ACTN1	4
MF	GO:0005484	SNAP receptor activity	8/2481	31/17697	0.05926	0.3824	0.3447	STX2/STX16/STX8/BET1/SNAP23/GOSR1/STX4/BNIP1	8
MF	GO:0035198	miRNA binding	8/2481	31/17697	0.05926	0.3824	0.3447	RBM4/MATR3/ZC3H12A/DDX21/ZC3H7A/NEAT1/ZC3H10/RC3H1	8
MF	GO:0005080	protein kinase C binding	12/2481	53/17697	0.05991	0.3824	0.3447	PRKCB/SQSTM1/PARD6G/TDG/ADCY4/HSPB1/ADCY6/LDB3/DACT2/PARD6A/PRKCSH/PARD6B	12
MF	GO:0017124	SH3 domain binding	25/2481	130/17697	0.06022	0.3824	0.3447	SOCS7/CIT/ARHGAP6/INPP5D/CABYR/WASF2/CTTNBP2/PLSCR4/CBL/SH3BGRL2/DPYSL3/DNM1/BCAR1/ENAH/AFAP1L2/KHDRBS1/KHDRBS3/UVRAG/PAK3/AFAP1L1/TP53BP2/HCLS1/LYN/EFS/SHANK3	25
MF	GO:0061659	ubiquitin-like protein ligase activity	41/2481	230/17697	0.06065	0.3824	0.3447	MYLIP/MED10/MSL2/RNF6/TRIM6/TRIM58/ARIH2/ITCH/MED7/UBR7/FBXO4/RNF183/TRAF6/TRIM24/RNF138/HECW2/UBE4B/RNF150/CBL/NEURL2/MED30/FBXL8/FANCL/RNF216/TRIM2/RLIM/LRSAM1/PDZRN3/NEURL1B/SKP2/RNF125/RNF139/RNF19B/CHFR/RNF103/ARIH1/KCMF1/MYCBP2/RNF220/RC3H1/RNF8	41
MF	GO:0044325	ion channel binding	24/2481	124/17697	0.06069	0.3824	0.3447	SRI/SCN1B/FGF13/DLG1/USP10/HERPUD1/DIAPH1/PDE4B/KCND3/STAC/YWHAZ/ANK1/ACTN1/FXYD1/FKBP1B/ANK2/FLNA/RYR2/CDH5/HSP90AB1/CAV1/PRKCSH/LYN/BAK1	24
MF	GO:0004709	MAP kinase kinase kinase activity	7/2481	26/17697	0.06175	0.3824	0.3447	MAP3K14/RAF1/MAP3K2/EGFR/MAP3K5/MAP3K1/MAP3K3	7
MF	GO:0030371	translation repressor activity	7/2481	26/17697	0.06175	0.3824	0.3447	PAIP2B/IREB2/RBM3/PAIP2/CELF1/CPEB1/CPEB2	7
MF	GO:0051787	misfolded protein binding	7/2481	26/17697	0.06175	0.3824	0.3447	CLU/EDEM1/SDF2L1/DNAJC10/DERL1/HSPA5/HSPA9	7
MF	GO:0001085	RNA polymerase II transcription factor binding	29/2481	155/17697	0.06188	0.3824	0.3447	IFI27/SPEN/MIER3/PPARG/EP300/GATA1/TBX5/BHLHE41/JUN/DHX9/TAL1/LDB1/BHLHE40/CREB1/CREBBP/FOS/MTA1/BBS1/TEAD4/KLF4/TBX2/GTF2E1/ZFPM2/TBX15/TBX22/TBX1/HCLS1/TAF1/SIN3A	29
MF	GO:0005521	lamin binding	5/2481	16/17697	0.06204	0.3824	0.3447	IFI27/AKAP8L/PLCB1/TMEM201/SUN2	5
MF	GO:0022841	potassium ion leak channel activity	5/2481	16/17697	0.06204	0.3824	0.3447	KCNK17/KCNK10/KCNK3/KCNK6/KCNK1	5
MF	GO:0043395	heparan sulfate proteoglycan binding	5/2481	16/17697	0.06204	0.3824	0.3447	CFH/LPL/AGRN/ITGA2/PTPRC	5
MF	GO:0016597	amino acid binding	13/2481	59/17697	0.06224	0.3824	0.3447	ALAS2/DDAH1/GNMT/SLC1A3/THNSL2/GPR143/SESN2/NOS3/ASS1/SLC1A1/SESN3/CPS1/GLRB	13
MF	GO:0005319	lipid transporter activity	25/2481	131/17697	0.06491	0.3966	0.3575	OSBP/GRAMD1B/OSBPL6/RFT1/PLEKHA3/OSBP2/APOF/C2CD2L/SLC10A2/ABCA4/PLSCR4/OSBPL9/CEACAM1/ABCA9/SLC10A7/MFSD2A/GLTP/STARD5/SLCO2A1/TRIAP1/PLTP/GRAMD1C/SLCO2B1/FABP3/APOL3	25
MF	GO:0015144	carbohydrate transmembrane transporter activity	9/2481	37/17697	0.06542	0.3975	0.3583	SLC2A5/SLC2A8/SLC45A1/AQP1/SLC2A6/SLC2A10/SLC2A12/SLC23A1/SLC17A5	9
MF	GO:0004674	protein serine/threonine kinase activity	73/2481	439/17697	0.06603	0.399	0.3597	LTBP1/DSTYK/ACVR1/MKNK2/ARAF/CIT/PRKY/PDPK1/CAMK2G/CDK16/MAPK11/PRKCB/EIF2AK4/SQSTM1/CLK1/STRADB/PINK1/CDK9/CDC42BPA/PPM1D/GTF2H3/HIPK1/AKAP13/SRPK2/ERN1/STK24/MAST3/MAP3K14/RAF1/RIOK1/MAP3K2/EGFR/ACVR2A/ULK2/MAP3K5/MAP3K1/DAPK2/BUB1B/CSNK1A1/PAK4/STK10/STK4/TTBK2/ALPK3/MELK/CLK3/PLK3/PLK1/SIK3/CDKL1/DCLK1/PRKAG2/CDK17/PKN3/HUNK/PKN2/PAK3/ALPK2/ADCK1/DCLK3/MAP3K3/MAPKAPK5/TTK/MTOR/TAF1/RPS6KA5/UHMK1/PHKA1/LTBP4/MARK1/ALPK1/CDK13/NEK2	73
MF	GO:0016410	N-acyltransferase activity	22/2481	113/17697	0.06655	0.4	0.3605	ALAS2/PHF20/NCOA3/POLE3/EP300/TAF10/HAT1/NAA16/ING3/NAA30/WDR5/CREBBP/GTF3C4/RSF1/HCFC1/MCM3AP/NAA25/TAF1/ALAS1/EPC1/NAA15/NCOA1	22
MF	GO:0140030	modification-dependent protein binding	27/2481	144/17697	0.06811	0.4072	0.367	BRD2/MSH6/TNFAIP3/ZFAND6/ANKRD13D/SQSTM1/YEATS2/CBX4/PHF13/ING3/ZRANB3/TNIP1/CHD1/WDR5/ANKRD13B/UBXN1/TRIM24/ANKRD13A/VCP/IDE/OTUD7B/ANK2/MBTD1/CHD5/LYN/TAF1/ING5	27
MF	GO:0001540	amyloid-beta binding	16/2481	78/17697	0.0729	0.4312	0.3886	CLU/C1QA/TGFB2/SORL1/FCGR2B/MSR1/GRIA3/RAMP3/IDE/TREM2/FZD5/PGRMC1/ITGA2/FZD4/CRYAB/EPHB2	16
MF	GO:0003724	RNA helicase activity	16/2481	78/17697	0.0729	0.4312	0.3886	DDX3Y/DHX57/DDX42/DHX9/DDX55/DDX19A/DDX21/DDX50/DDX52/IFIH1/DDX10/DDX54/DDX60L/EIF4A1/DDX46/DDX6	16
MF	GO:0032452	histone demethylase activity	7/2481	27/17697	0.07368	0.4312	0.3886	UTY/KDM5D/KDM6B/KDM2A/JMJD6/JMJD1C/JARID2	7
MF	GO:0045499	chemorepellent activity	7/2481	27/17697	0.07368	0.4312	0.3886	SEMA3B/SEMA3G/SEMA4D/SEMA6D/SEMA5B/FLRT2/SEMA3E	7
MF	GO:0004596	peptide alpha-N-acetyltransferase activity	4/2481	12/17697	0.07522	0.4356	0.3926	NAA16/NAA30/NAA25/NAA15	4
MF	GO:0061578	Lys63-specific deubiquitinase activity	4/2481	12/17697	0.07522	0.4356	0.3926	PSMD14/TNFAIP3/OTUD4/CYLD	4
MF	GO:0030676	Rac guanyl-nucleotide exchange factor activity	5/2481	17/17697	0.07812	0.4477	0.4035	EPS8/VAV1/FARP1/VAV3/EPS8L1	5
MF	GO:0051010	microtubule plus-end binding	5/2481	17/17697	0.07812	0.4477	0.4035	APC/CLASP2/TTBK2/KIF2C/CLASP1	5
MF	GO:0003730	mRNA 3'-UTR binding	18/2481	91/17697	0.07998	0.4559	0.4109	RBM4/PABPC4/FXR1/ZFP36/RBM3/LARP1/MIR21/ZC3H12A/PABPC3/RSL1D1/ILF3/CPEB1/PABPC4L/RBMS3/RPS7/RC3H1/CRYZ/CPEB2	18
MF	GO:0070851	growth factor receptor binding	25/2481	134/17697	0.08048	0.4559	0.4109	ITGB3/TRIP6/SLC9A3R1/VEGFC/IL1R1/ERN1/FGF18/ECM1/IL23R/EGF/FLRT2/PDGFRA/CBL/IL12A/IL2/FRS2/PDGFRB/IL1B/CD300LF/VAV3/EFEMP1/TLR9/CDH5/LYN/KL	25
MF	GO:0042393	histone binding	35/2481	197/17697	0.08089	0.4559	0.4109	BRD2/MSH6/HJURP/SPTY2D1/PRKCB/SNCA/HAT1/IPO9/YEATS2/CBX4/PHF13/SFMBT2/MLLT10/ING3/IPO7/CHD1/WDR5/PARP9/SMARCC1/SIRT1/TRIM24/RSF1/MCM3AP/DTX3L/WDTC1/CHD2/MBTD1/CHD5/CTCFL/EZH1/SET/TAF1/ANP32B/RNF8/ING5	35
MF	GO:0008187	poly-pyrimidine tract binding	8/2481	33/17697	0.0812	0.4559	0.4109	PABPC4/RBM3/PABPC3/IFIT5/KHDRBS1/PABPC4L/RBMS3/RPS7	8
MF	GO:0051018	protein kinase A binding	11/2481	50/17697	0.08276	0.4599	0.4146	WASF2/AKAP8L/PRKAR2A/ARFGEF2/AKAP13/WASF1/SOX9/DACT2/RYR2/AKAP8/PRKAR2B	11
MF	GO:0070888	E-box binding	11/2481	50/17697	0.08276	0.4599	0.4146	PPARG/BHLHE41/TWIST1/SFPQ/ARNTL2/TAL1/BHLHE40/HES1/MAX/NONO/PER1	11
MF	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	12/2481	56/17697	0.08487	0.4693	0.423	HBB/HBD/PRDX2/CYGB/PXDN/HBM/SESN2/LOXHD1/GSTT1/SESN3/GPX8/HBQ1	12
MF	GO:0004252	serine-type endopeptidase activity	29/2481	160/17697	0.08577	0.4719	0.4254	HTRA4/MMP8/MBTPS1/CTSG/HTRA1/PROC/LTF/MMP1/ELANE/C2/CFB/RHBDD3/PCSK6/TPSAB1/HTRA3/TPP2/HP/MMP3/MMP9/C1RL/PLAT/C1R/FAP/RHBDL2/TPSG1/C1S/CFI/MST1/PRSS2	29
MF	GO:0004407	histone deacetylase activity	7/2481	28/17697	0.08688	0.4728	0.4261	SIRT2/BRMS1L/SIRT1/SUDS3/SIRT7/SIN3B/SIN3A	7
MF	GO:0017056	structural constituent of nuclear pore	7/2481	28/17697	0.08688	0.4728	0.4261	NUP93/NUP153/NUP188/NUP160/NUP54/NUP214/NUP155	7
MF	GO:0030295	protein kinase activator activity	16/2481	80/17697	0.08763	0.4728	0.4261	FAM20A/SPRY2/FGF13/LTF/GHRL/TGFB1/GAS6/RPLP1/CCNT2/EGF/STK4/DBF4/AFAP1L2/PRKAG2/CDK5R1/MADD	16
MF	GO:0051117	ATPase binding	16/2481	80/17697	0.08763	0.4728	0.4261	GABARAPL2/ATP6V1E1/SDF2L1/ATP1B2/ATP6V0A2/UBXN1/ATP6V1G3/DNAJC10/DERL1/UBE4B/ANK1/NUFIP1/ANK2/CAV1/WFS1/NKAIN1	16
MF	GO:0016791	phosphatase activity	46/2481	270/17697	0.09075	0.4728	0.4261	PPTC7/PTP4A2/DUSP28/INPP5D/CAMK2G/PTPRO/PTPN13/PTP4A1/PPM1J/DLG1/DUSP10/PPP2CA/SSH1/PFKFB2/PPM1D/PTP4A3/PTPRH/PPEF2/CTDSPL/ALPL/NT5DC3/PTPN21/MTMR14/PTPRF/PDP1/PPM1A/MTM1/ACP5/PTPRG/PPP3CB/PTPN14/PPM1F/RNGTT/DUSP1/INPP5F/DUSP18/PPEF1/MTMR7/STYXL1/PPP1R3C/MTMR4/PTPRC/CDKN3/SSH3/PPM1N/PTPRB	46
MF	GO:0030215	semaphorin receptor binding	6/2481	23/17697	0.09216	0.4728	0.4261	SEMA3B/SEMA3G/SEMA4D/SEMA6D/SEMA5B/SEMA3E	6
MF	GO:0030552	cAMP binding	6/2481	23/17697	0.09216	0.4728	0.4261	PRKAR2A/PDE2A/PDE4B/RAPGEF3/PRKAR2B/RAPGEF4	6
MF	GO:0031406	carboxylic acid binding	34/2481	193/17697	0.09235	0.4728	0.4261	ALAS2/LCN12/DDAH1/GNMT/PPARG/PLOD2/FABP5/SLC1A3/AGRN/SELP/CYP26B1/THNSL2/PAM/APOC1/GPR143/SESN2/NOS3/ASS1/SLC1A1/PRR7/AKR1C2/NR2F2/SESN3/CRABP1/CYP27C1/HAPLN1/CPS1/LYVE1/STARD5/ACAN/GLRB/NR1H4/FABP3/HMGCL	34
MF	GO:0008022	protein C-terminus binding	33/2481	187/17697	0.09435	0.4728	0.4261	GRIP1/XRCC6/PPARG/EP300/NIPBL/DLG1/BCL10/SARNP/PPP2CA/PHB2/BCAM/FN1/USP7/DAB2/SIRT1/ECM1/MCHR1/CNRIP1/CEP135/FOXN3/KPNA3/SCLT1/HIC2/DNM1/KCNK3/MYO1C/YAP1/MPDZ/MIF4GD/FBLN1/CORO1A/MKI67/SHANK3	33
MF	GO:0005516	calmodulin binding	35/2481	200/17697	0.09541	0.4728	0.4261	ADCY3/IQGAP3/MKNK2/CAMK2G/MBP/MARCKSL1/KCNN3/CALD1/ARPP21/EGFR/NOS3/UBR4/DAPK2/EEF1A1/PLCB1/CEACAM1/MAP2/GAP43/RIT1/MYO1C/MYH9/PDE1A/PPP3CB/TJP1/SPATA17/RYR2/EWSR1/MAPKAPK5/MYH10/PCYT1A/WFS1/UNC13B/PHKA1/MYO5C/MYO15A	35
MF	GO:0004860	protein kinase inhibitor activity	13/2481	63/17697	0.09543	0.4728	0.4261	SPRY2/SH3BP5L/PRKAR2A/CDKN1C/CDKN2C/ITPRIP/SMCR8/HSPB1/PKIB/PRKAG2/IBTK/CDKN2B/PRKAR2B	13
MF	GO:0005416	amino acid:cation symporter activity	5/2481	18/17697	0.0962	0.4728	0.4261	SLC6A8/SLC1A3/SLC1A1/SLC32A1/SLC6A1	5
MF	GO:0016755	transferase activity, transferring amino-acyl groups	5/2481	18/17697	0.0962	0.4728	0.4261	EPB42/TGM4/GGT5/F13A1/ATE1	5
MF	GO:0035613	RNA stem-loop binding	5/2481	18/17697	0.0962	0.4728	0.4261	DHX9/ZC3H12A/MYH10/RC3H1/LARP6	5
MF	GO:0038191	neuropilin binding	5/2481	18/17697	0.0962	0.4728	0.4261	SEMA3B/SEMA3G/SEMA4D/SEMA6D/SEMA3E	5
MF	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	5/2481	18/17697	0.0962	0.4728	0.4261	PRKAR2A/PDE2A/PDE1A/PDE6G/PRKAR2B	5
MF	GO:0070064	proline-rich region binding	5/2481	18/17697	0.0962	0.4728	0.4261	CCND1/CYLD/YAP1/GHR/PFN1	5
MF	GO:0016251	RNA polymerase II general transcription initiation factor activity	4/2481	13/17697	0.09703	0.4728	0.4261	TAF10/GTF2H3/GTF2E1/TAF1	4
MF	GO:0017070	U6 snRNA binding	4/2481	13/17697	0.09703	0.4728	0.4261	LSM4/EIF5A/RBM22/LSM7	4
MF	GO:0031404	chloride ion binding	4/2481	13/17697	0.09703	0.4728	0.4261	TDG/ACE/NLGN4X/CLCN4	4
MF	GO:0031434	mitogen-activated protein kinase kinase binding	4/2481	13/17697	0.09703	0.4728	0.4261	DLG1/ACE/RAF1/PIN1	4
MF	GO:0034236	protein kinase A catalytic subunit binding	4/2481	13/17697	0.09703	0.4728	0.4261	PRKAR2A/SOX9/RYR2/PRKAR2B	4
MF	GO:0042043	neurexin family protein binding	4/2481	13/17697	0.09703	0.4728	0.4261	SYTL4/CPE/SYTL1/NLGN4X	4
MF	GO:0045159	myosin II binding	4/2481	13/17697	0.09703	0.4728	0.4261	SLC9A3R1/MYL4/SHROOM4/LIMCH1	4
MF	GO:0052744	phosphatidylinositol monophosphate phosphatase activity	4/2481	13/17697	0.09703	0.4728	0.4261	MTMR14/MTM1/INPP5F/MTMR7	4
MF	GO:0072542	protein phosphatase activator activity	4/2481	13/17697	0.09703	0.4728	0.4261	PPP1R15A/PHACTR4/PPP2R5E/IGFBP3	4
MF	GO:0033558	protein deacetylase activity	7/2481	29/17697	0.1013	0.484	0.4362	SIRT2/BRMS1L/SIRT1/SUDS3/SIRT7/SIN3B/SIN3A	7
MF	GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	7/2481	29/17697	0.1013	0.484	0.4362	DHRS9/HSD3B7/HSD11B2/HSD17B14/HSD11B1/HSD17B1/HSD17B3	7
MF	GO:0043539	protein serine/threonine kinase activator activity	7/2481	29/17697	0.1013	0.484	0.4362	FAM20A/SPRY2/LTF/TGFB1/STK4/DBF4/CDK5R1	7
MF	GO:0005048	signal sequence binding	10/2481	46/17697	0.1015	0.484	0.4362	TOMM20/NFKBIA/NOLC1/KPNA1/NUP153/KPNA3/NUP214/KDELR3/IPO5/SRP54	10
MF	GO:0008307	structural constituent of muscle	10/2481	46/17697	0.1015	0.484	0.4362	MYL9/MYL6B/TPM1/NEXN/ASPH/OBSL1/SMTN/CSRP2/DMD/CSRP1	10
MF	GO:0031072	heat shock protein binding	22/2481	119/17697	0.1038	0.4926	0.4439	TFAM/BCOR/SNCA/DNAJA1/FKBP4/CREB1/ZFP36/PPEF2/ERN1/PPID/TELO2/DNAJB14/DNAJC10/DNAJA4/NR3C1/HSP90AB1/DNAJA2/BAK1/KDR/SPN/HSPA5/HSPA9	22
MF	GO:0033293	monocarboxylic acid binding	13/2481	64/17697	0.1051	0.497	0.4479	LCN12/PPARG/FABP5/CYP26B1/APOC1/PRR7/AKR1C2/NR2F2/CRABP1/CYP27C1/STARD5/NR1H4/FABP3	13
MF	GO:0005501	retinoid binding	8/2481	35/17697	0.1073	0.5051	0.4553	LCN12/FABP5/CYP26B1/NR2F2/CRABP1/CYP27C1/ALDH1A2/RBP1	8
MF	GO:0008143	poly(A) binding	6/2481	24/17697	0.109	0.5065	0.4565	PABPC4/PABPC3/RBPMS/KHDRBS1/PABPC4L/RBMS3	6
MF	GO:0008198	ferrous iron binding	6/2481	24/17697	0.109	0.5065	0.4565	SNCA/FXN/CDO1/DNAJC24/ACP5/HEPH	6
MF	GO:0120013	intermembrane lipid transfer activity	6/2481	24/17697	0.109	0.5065	0.4565	OSBP/GRAMD1B/GLTP/STARD5/PLTP/GRAMD1C	6
MF	GO:0004879	nuclear receptor activity	10/2481	47/17697	0.1136	0.5157	0.4648	PPARG/RXRB/THRB/NR2F2/NR1D2/NR2F6/NR3C1/NR4A2/NR1H4/NR5A2	10
MF	GO:0098531	transcription factor activity, direct ligand regulated sequence-specific DNA binding	10/2481	47/17697	0.1136	0.5157	0.4648	PPARG/RXRB/THRB/NR2F2/NR1D2/NR2F6/NR3C1/NR4A2/NR1H4/NR5A2	10
MF	GO:0005506	iron ion binding	27/2481	152/17697	0.1137	0.5157	0.4648	CYP11A1/PLOD2/SNCA/LTF/FXN/CDO1/CYP4F2/CH25H/LCN2/CYP4F3/CYGB/CYP26B1/PPEF2/CYP21A2/JMJD6/DNAJC24/CYP27C1/ACP5/HBQ1/AOX1/CYP2F1/CYP3A5/PPEF1/CYP20A1/CYP39A1/ABCE1/HEPH	27
MF	GO:0097110	scaffold protein binding	12/2481	59/17697	0.1155	0.5157	0.4648	CIT/CAV2/HSP90AA1/NOS3/KCNA5/CRIPT/TREM2/NLGN4X/DYNLL2/TCOF1/SHANK3/KRT5	12
MF	GO:0004622	lysophospholipase activity	5/2481	19/17697	0.1162	0.5157	0.4648	PLA2G4C/MGLL/LYPLAL1/GDPD1/ENPP2	5
MF	GO:0005086	ARF guanyl-nucleotide exchange factor activity	5/2481	19/17697	0.1162	0.5157	0.4648	SEC61B/HERC1/ARFGEF2/PSD3/FBXO8	5
MF	GO:0016500	protein-hormone receptor activity	5/2481	19/17697	0.1162	0.5157	0.4648	IGF1R/MCHR1/ADIPOR2/RXFP2/GPR173	5
MF	GO:0022840	leak channel activity	5/2481	19/17697	0.1162	0.5157	0.4648	KCNK17/KCNK10/KCNK3/KCNK6/KCNK1	5
MF	GO:0022842	narrow pore channel activity	5/2481	19/17697	0.1162	0.5157	0.4648	KCNK17/KCNK10/KCNK3/KCNK6/KCNK1	5
MF	GO:0031681	G-protein beta-subunit binding	5/2481	19/17697	0.1162	0.5157	0.4648	RGS7/GNG11/GNG12/GNGT2/GNG10	5
MF	GO:0070696	transmembrane receptor protein serine/threonine kinase binding	5/2481	19/17697	0.1162	0.5157	0.4648	INHBA/BMP2/BMP8A/MAGI2/CDH5	5
MF	GO:0008519	ammonium transmembrane transporter activity	7/2481	30/17697	0.117	0.5157	0.4648	SLC18A1/SLC6A8/RHD/RHCE/AQP1/SLC44A2/SLC25A29	7
MF	GO:0015294	solute:cation symporter activity	19/2481	102/17697	0.117	0.5157	0.4648	SLC15A4/SLC18A1/SLC6A8/SLC25A3/SLC1A3/SLC10A2/SLC20A1/SLC2A8/SLC12A8/SLC45A1/SLC1A1/SLC28A3/SLC2A6/SLC32A1/SLC2A10/SLC2A12/SLC23A1/SLC17A5/SLC6A1	19
MF	GO:0032182	ubiquitin-like protein binding	18/2481	96/17697	0.1189	0.522	0.4705	SIRT2/UBXN7/TNFAIP3/SQSTM1/TDG/CBX4/USPL1/FBXW7/UBXN1/HSPB1/UCHL1/PML/SOBP/RAE1/NR3C1/RNF19B/AUP1/RNF8	18
MF	GO:0005095	GTPase inhibitor activity	4/2481	14/17697	0.1214	0.5227	0.4711	RTKN/IPO5/SLIT2/CPEB2	4
MF	GO:0005283	amino acid:sodium symporter activity	4/2481	14/17697	0.1214	0.5227	0.4711	SLC6A8/SLC1A3/SLC1A1/SLC6A1	4
MF	GO:0030983	mismatched DNA binding	4/2481	14/17697	0.1214	0.5227	0.4711	MSH6/PMS1/TDG/MLH3	4
MF	GO:0019825	oxygen binding	8/2481	36/17697	0.1219	0.5227	0.4711	HBB/HBD/CYGB/HBM/HBQ1/NOX4/CYP2F1/CYP3A5	8
MF	GO:0019840	isoprenoid binding	8/2481	36/17697	0.1219	0.5227	0.4711	LCN12/FABP5/CYP26B1/NR2F2/CRABP1/CYP27C1/ALDH1A2/RBP1	8
MF	GO:0030551	cyclic nucleotide binding	8/2481	36/17697	0.1219	0.5227	0.4711	PRKAR2A/PDE2A/PDE4B/RAPGEF3/FKBP1B/PDE6G/PRKAR2B/RAPGEF4	8
MF	GO:0030544	Hsp70 protein binding	9/2481	42/17697	0.1249	0.5333	0.4806	SNCA/DNAJA1/CREB1/PPEF2/ERN1/PPID/DNAJB14/DNAJC10/SPN	9
MF	GO:0004222	metalloendopeptidase activity	19/2481	103/17697	0.1256	0.5343	0.4816	ADAMTS2/MME/MMP8/MMP1/PHEX/ADAM32/ADAMTS9/ADAMTS14/MMEL1/MMP3/ADAMTS15/MMP9/IDE/MMP19/FAP/ADAMTS16/SPG7/ADAMTS12/MMP25	19
MF	GO:0033612	receptor serine/threonine kinase binding	6/2481	25/17697	0.1273	0.5373	0.4843	FADD/INHBA/BMP2/BMP8A/MAGI2/CDH5	6
MF	GO:0048027	mRNA 5'-UTR binding	6/2481	25/17697	0.1273	0.5373	0.4843	LARP1/RPS3A/RSL1D1/RPS7/MYH10/LARP6	6