ONTOLOGY	ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	qvalue	geneID	Count
KEGG	hsa04218	Cellular senescence	22/652	156/8135	0.006365	0.8543	0.8543	ITPR2/CCNA1/ATR/PPP3R1/RAD50/HLA-B/IL6/CDK1/E2F2/CALM3/PPID/RAD9B/CDKN2B/MTOR/FOXO3/HLA-G/HIPK2/PPP3CA/TRPV4/PIK3R1/MAPK12/E2F1	22
KEGG	hsa04657	IL-17 signaling pathway	15/652	94/8135	0.00743	0.8543	0.8543	LCN2/MMP9/CXCL5/S100A8/IKBKB/S100A9/CXCL1/ANAPC5/IL6/USP25/DEFB4A/HSP90AA1/IL17RC/CCL7/MAPK12	15
KEGG	hsa04659	Th17 cell differentiation	16/652	108/8135	0.01178	0.8543	0.8543	HLA-DPB1/PPP3R1/IKBKB/HLA-DPA1/RXRB/IL6/EBI3/HLA-DOA/IFNGR1/IL1RAP/MTOR/HSP90AA1/STAT5A/PPP3CA/JAK3/MAPK12	16
KEGG	hsa00280	Valine, leucine and isoleucine degradation	9/652	48/8135	0.01275	0.8543	0.8543	MCCC1/HIBADH/PCCA/ACADS/ABAT/EHHADH/MCEE/AUH/IVD	9
KEGG	hsa03450	Non-homologous end-joining	4/652	13/8135	0.01628	0.8543	0.8543	RAD50/DCLRE1C/PRKDC/NHEJ1	4
KEGG	hsa05202	Transcriptional misregulation in cancer	24/652	193/8135	0.02015	0.8543	0.8543	ELANE/MMP9/BCL2L1/MPO/CEBPE/IL1R2/CCNA1/HDAC2/HPGD/TLX3/ZBTB16/DEFA4/TLX1/PPARG/NTRK1/WNT16/RXRB/IL6/POLK/NGFR/SMAD1/ATF1/KDM6A/BAK1	24
KEGG	hsa05150	Staphylococcus aureus infection	14/652	96/8135	0.02019	0.8543	0.8543	CAMP/HLA-DPB1/HLA-DPA1/DEFA4/C3AR1/C1QB/C1QA/HLA-DOA/DEFB4A/FCGR2B/FPR2/KRT13/FCGR3B/KRT19	14
KEGG	hsa04640	Hematopoietic cell lineage	14/652	99/8135	0.02573	0.8543	0.8543	HLA-DPB1/CR1L/IL1R2/GYPA/MME/HLA-DPA1/TFRC/IL7/ITGB3/GP1BB/IL6/HLA-DOA/GP9/ITGA2B	14
KEGG	hsa04974	Protein digestion and absorption	14/652	103/8135	0.03476	0.8543	0.8543	COL17A1/COL10A1/MME/CPA2/COL4A6/CELA2B/PRSS2/ATP1A1/COL9A3/COL18A1/PRSS3/SLC8A3/KCNK5/COL6A6	14
KEGG	hsa05168	Herpes simplex virus 1 infection	51/652	495/8135	0.03554	0.8543	0.8543	ZNF354B/ZFP90/HLA-DPB1/ZNF763/BCL2L1/ZNF175/ZNF490/ZNF283/ZNF823/ZNF404/ZNF879/IKBKB/HLA-DPA1/DDX58/HLA-B/EIF2AK1/ZNF555/ZNF780B/ZNF205/RBAK/ITGB3/ZNF846/ZNF3/ZNF25/IL6/ZNF182/RNASEL/HLA-DOA/ZNF791/ZNF566/ZNF440/DAXX/IFNGR1/ZNF443/ZNF620/ZNF93/SOCS3/MTOR/ZNF41/ZNF630/ZNF585A/HLA-G/ZNF674/ZNF212/ZNF417/BAK1/PIK3R1/IFNA5/ZNF284/ZNF234/ZNF235	51
KEGG	hsa00640	Propanoate metabolism	6/652	32/8135	0.03901	0.8543	0.8543	PCCA/ACADS/ABAT/EHHADH/LDHC/MCEE	6
KEGG	hsa00910	Nitrogen metabolism	4/652	17/8135	0.04199	0.8543	0.8543	CA1/CA4/CA2/GLUL	4
KEGG	hsa05219	Bladder cancer	7/652	41/8135	0.04231	0.8543	0.8543	MMP9/RPS6KA5/DAPK3/E2F2/FGFR3/ERBB2/E2F1	7
KEGG	hsa04924	Renin secretion	10/652	69/8135	0.04708	0.8543	0.8543	ITPR2/EDN3/PPP3R1/CALM3/NPR1/KCNJ2/ACE/NPPA/ADCYAP1R1/PPP3CA	10
KEGG	hsa05230	Central carbon metabolism in cancer	10/652	70/8135	0.05117	0.8543	0.8543	GLS/NTRK1/FGFR3/LDHC/MTOR/ERBB2/GCK/SLC7A5/PFKM/PIK3R1	10
KEGG	hsa05166	Human T-cell leukemia virus 1 infection	25/652	222/8135	0.05145	0.8543	0.8543	HLA-DPB1/POLB/BCL2L1/IL1R2/CCNA1/ATR/PPP3R1/IKBKB/HLA-DPA1/HLA-B/ANAPC5/IL6/HLA-DOA/ADCY3/E2F2/CDKN2B/TLN1/NFYB/HLA-G/STAT5A/PPP3CA/JAK3/PIK3R1/E2F1/ANAPC7	25
KEGG	hsa00590	Arachidonic acid metabolism	9/652	61/8135	0.05257	0.8543	0.8543	CYP4F2/PTGIS/CYP4F3/PLA2G4C/CYP2U1/PLA2G10/PTGES3/CYP2C9/PLA2G1B	9
KEGG	hsa04360	Axon guidance	21/652	182/8135	0.05674	0.8543	0.8543	ROCK2/SEMA4B/PPP3R1/SEMA3B/LIMK2/PARD6G/PLXNB1/CAMK2G/ABLIM3/ROBO3/DPYSL5/EPHB4/SRGAP1/EPHB2/PARD6B/SEMA3F/EPHB3/EFNA4/PPP3CA/SEMA3G/PIK3R1	21
KEGG	hsa05223	Non-small cell lung cancer	10/652	72/8135	0.06004	0.8543	0.8543	RXRB/POLK/E2F2/FOXO3/ERBB2/STAT5A/BAK1/JAK3/PIK3R1/E2F1	10
KEGG	hsa04966	Collecting duct acid secretion	5/652	27/8135	0.06024	0.8543	0.8543	SLC4A1/ATP6V1G3/CA2/ATP6V1B1/ATP6V1E1	5
KEGG	hsa04621	NOD-like receptor signaling pathway	21/652	184/8135	0.06235	0.8543	0.8543	CAMP/ITPR2/BCL2L1/NOD1/IKBKB/ATG12/GBP4/MAP1LC3A/DEFA4/CXCL1/IL6/RNASEL/NLRP6/MFN1/DEFB4A/HSP90AA1/BRCC3/NEK7/RIPK3/MAPK12/IFNA5	21
KEGG	hsa04658	Th1 and Th2 cell differentiation	12/652	92/8135	0.0627	0.8543	0.8543	HLA-DPB1/RBPJL/PPP3R1/IKBKB/HLA-DPA1/HLA-DOA/IFNGR1/DLL3/STAT5A/PPP3CA/JAK3/MAPK12	12
KEGG	hsa05222	Small cell lung cancer	12/652	92/8135	0.0627	0.8543	0.8543	BCL2L1/IKBKB/RXRB/POLK/COL4A6/E2F2/CDKN2B/SKP2/ITGA2B/BAK1/PIK3R1/E2F1	12
KEGG	hsa05146	Amoebiasis	13/652	102/8135	0.06309	0.8543	0.8543	ARG1/SERPINB10/CTSG/IL1R2/ACTN1/MUC2/CXCL1/IL6/COL4A6/SERPINB6/GNAL/RAB5B/PIK3R1	13
KEGG	hsa04144	Endocytosis	27/652	251/8135	0.07019	0.8634	0.8634	RAB22A/SNF8/RABEP1/FOLR3/PDCD6IP/AMPH/PARD6G/HLA-B/VPS35/TFRC/PRKCI/CAPZA3/EEA1/CXCR1/GBF1/FGFR3/VPS36/HSPA1A/PARD6B/RAB5B/ACTR3B/HLA-G/SH3GLB1/EHD1/VTA1/GRK1/RUFY2	27
KEGG	hsa05216	Thyroid cancer	6/652	37/8135	0.0716	0.8634	0.8634	PPARG/NTRK1/RXRB/POLK/CCDC6/BAK1	6
KEGG	hsa04610	Complement and coagulation cascades	11/652	85/8135	0.07601	0.8634	0.8634	CR1L/KNG1/F2/C3AR1/C1QB/F2RL3/CD46/C1QA/C4BPA/CLU/F9	11
KEGG	hsa05221	Acute myeloid leukemia	9/652	67/8135	0.08526	0.8634	0.8634	MPO/CEBPE/CCNA1/IKBKB/ZBTB16/MTOR/STAT5A/PIK3R1/PPARD	9
KEGG	hsa04922	Glucagon signaling pathway	13/652	107/8135	0.08526	0.8634	0.8634	ITPR2/PYGB/PPP3R1/PHKB/CAMK2G/CALM3/LDHC/GCK/SIK2/GYS2/PFKM/PPP3CA/GCGR	13
KEGG	hsa04514	Cell adhesion molecules	17/652	149/8135	0.0872	0.8634	0.8634	HLA-DPB1/NLGN2/CLDN5/OCLN/HLA-DPA1/HLA-B/CLDN14/CDH2/NLGN4Y/HLA-DOA/CNTN2/CDH15/CLDN8/HLA-G/CLDN6/CLDN10/PDCD1	17
KEGG	hsa05226	Gastric cancer	17/652	149/8135	0.0872	0.8634	0.8634	APC/WNT1/MUC2/WNT16/RXRB/POLK/E2F2/WNT2/MLH1/CDKN2B/MTOR/ERBB2/FGF3/FGF22/BAK1/PIK3R1/E2F1	17
KEGG	hsa03013	Nucleocytoplasmic transport	13/652	108/8135	0.09022	0.8634	0.8634	UPF3B/IPO9/IPO7/NUP214/ACIN1/NUP205/XPO5/THOC2/SENP2/TNPO3/SAP18/NUP88/NUP50	13
KEGG	hsa00220	Arginine biosynthesis	4/652	22/8135	0.0943	0.8634	0.8634	ARG1/GLS/GLUL/GOT1L1	4
KEGG	hsa00410	beta-Alanine metabolism	5/652	31/8135	0.09783	0.8634	0.8634	CSAD/SMOX/ACADS/ABAT/EHHADH	5
KEGG	hsa05310	Asthma	5/652	31/8135	0.09783	0.8634	0.8634	RNASE3/HLA-DPB1/HLA-DPA1/FCER1A/HLA-DOA	5
KEGG	hsa04061	Viral protein interaction with cytokine and cytokine receptor	12/652	100/8135	0.1025	0.8634	0.8634	CXCL5/CCL22/CXCL1/CCR4/IL6/CXCR1/IL20RA/PF4V1/IL22RA1/CCL7/CCL24/IL34	12
KEGG	hsa04964	Proximal tubule bicarbonate reclamation	4/652	23/8135	0.1073	0.8634	0.8634	CA4/GLS/CA2/ATP1A1	4
KEGG	hsa04550	Signaling pathways regulating pluripotency of stem cells	16/652	143/8135	0.1081	0.8634	0.8634	APC/WNT1/ACVR2B/TBX3/HOXA1/WNT16/RIF1/FGFR3/WNT2/SMAD1/SOX2/LHX5/ESRRB/JAK3/PIK3R1/MAPK12	16
KEGG	hsa04136	Autophagy - other	5/652	32/8135	0.1087	0.8634	0.8634	ATG12/PIK3R4/MTOR/ATG4A/ATG10	5
KEGG	hsa05332	Graft-versus-host disease	6/652	42/8135	0.116	0.8634	0.8634	HLA-DPB1/HLA-DPA1/HLA-B/IL6/HLA-DOA/HLA-G	6
KEGG	hsa04611	Platelet activation	14/652	124/8135	0.1201	0.8634	0.8634	ITPR2/ROCK2/PLA2G4C/F2/PRKCI/ITGB3/F2RL3/GP1BB/ADCY3/GP9/TLN1/ITGA2B/PIK3R1/MAPK12	14
KEGG	hsa00051	Fructose and mannose metabolism	5/652	33/8135	0.1202	0.8634	0.8634	KHK/PMM2/ENOSF1/AKR1B1/PFKM	5
KEGG	hsa04940	Type I diabetes mellitus	6/652	43/8135	0.1263	0.8634	0.8634	HLA-DPB1/PTPRN2/HLA-DPA1/HLA-B/HLA-DOA/HLA-G	6
KEGG	hsa04975	Fat digestion and absorption	6/652	43/8135	0.1263	0.8634	0.8634	LIPF/AGPAT1/CLPS/MOGAT3/PLA2G10/PLA2G1B	6
KEGG	hsa01524	Platinum drug resistance	9/652	73/8135	0.1278	0.8634	0.8634	BCL2L1/REV3L/GSTM4/MSH2/MLH1/ERBB2/TOP2B/BAK1/PIK3R1	9
KEGG	hsa05320	Autoimmune thyroid disease	7/652	53/8135	0.1287	0.8634	0.8634	HLA-DPB1/HLA-DPA1/HLA-B/HLA-DOA/TG/HLA-G/IFNA5	7
KEGG	hsa05169	Epstein-Barr virus infection	21/652	202/8135	0.1305	0.8634	0.8634	HLA-DPB1/CCNA1/RBPJL/HDAC2/IKBKB/HLA-DPA1/PSMD12/DDX58/HLA-B/IL6/POLK/HLA-DOA/E2F2/SKP2/HLA-G/BAK1/JAK3/PIK3R1/MAPK12/IFNA5/E2F1	21
KEGG	hsa05152	Tuberculosis	19/652	180/8135	0.1306	0.8634	0.8634	CAMP/HLA-DPB1/CR1L/PPP3R1/HLA-DPA1/EEA1/IL6/HLA-DOA/CAMK2G/CALM3/RFXAP/IFNGR1/FCGR2B/RAB5B/NFYB/FCGR3B/PPP3CA/MAPK12/IFNA5	19
KEGG	hsa04110	Cell cycle	14/652	126/8135	0.1319	0.8634	0.8634	CCNA1/HDAC2/ATR/PLK1/CDC25C/ANAPC5/CDK1/E2F2/PKMYT1/CDKN2B/PRKDC/SKP2/E2F1/ANAPC7	14
KEGG	hsa00592	alpha-Linolenic acid metabolism	4/652	25/8135	0.1355	0.8634	0.8634	PLA2G4C/FADS2/PLA2G10/PLA2G1B	4
KEGG	hsa04962	Vasopressin-regulated water reabsorption	6/652	44/8135	0.1369	0.8634	0.8634	AVPR2/DCTN6/ADCY3/DCTN5/RAB5B/DYNC2LI1	6
KEGG	hsa05167	Kaposi sarcoma-associated herpesvirus infection	20/652	194/8135	0.1456	0.8634	0.8634	ITPR2/PPP3R1/IKBKB/MAP1LC3A/HLA-B/CXCL1/CCR4/IL6/E2F2/CALM3/MICA/IFNGR1/MTOR/HLA-G/PPP3CA/BAK1/PIK3R1/MAPK12/IFNA5/E2F1	20
KEGG	hsa04971	Gastric acid secretion	9/652	76/8135	0.1527	0.8634	0.8634	ITPR2/KCNK10/CA2/ADCY3/CAMK2G/CALM3/KCNJ2/ATP1A1/KCNJ15	9
KEGG	hsa05212	Pancreatic cancer	9/652	76/8135	0.1527	0.8634	0.8634	BCL2L1/IKBKB/POLK/E2F2/MTOR/ERBB2/BAK1/PIK3R1/E2F1	9
KEGG	hsa05220	Chronic myeloid leukemia	9/652	76/8135	0.1527	0.8634	0.8634	BCL2L1/HDAC2/IKBKB/POLK/E2F2/STAT5A/BAK1/PIK3R1/E2F1	9
KEGG	hsa04145	Phagosome	16/652	152/8135	0.158	0.8634	0.8634	HLA-DPB1/MPO/ATP6V1G3/HLA-DPA1/HLA-B/TFRC/ITGB3/EEA1/HLA-DOA/ATP6V1B1/ATP6V1E1/FCGR2B/RAB5B/STX18/HLA-G/FCGR3B	16
KEGG	hsa04750	Inflammatory mediator regulation of TRP channels	11/652	98/8135	0.1599	0.8634	0.8634	ITPR2/PLA2G4C/KNG1/NTRK1/ADCY3/CAMK2G/CALM3/IL1RAP/TRPV4/PIK3R1/MAPK12	11
KEGG	hsa04612	Antigen processing and presentation	9/652	78/8135	0.1705	0.8634	0.8634	HLA-DPB1/HLA-DPA1/HLA-B/HLA-DOA/RFXAP/HSPA1A/HSP90AA1/NFYB/HLA-G	9
KEGG	hsa04921	Oxytocin signaling pathway	16/652	154/8135	0.1705	0.8634	0.8634	ITPR2/ROCK2/PLA2G4C/PPP3R1/RYR1/ADCY3/CACNG2/CAMK2G/CALM3/NPR1/KCNJ2/NPPA/KCNJ12/CACNB2/MAP2K5/PPP3CA	16
KEGG	hsa03018	RNA degradation	9/652	79/8135	0.1797	0.8634	0.8634	PAN2/TOB2/C1D/CNOT10/PABPC1L/CNOT1/PFKM/DIS3L/CNOT4	9
KEGG	hsa05213	Endometrial cancer	7/652	58/8135	0.18	0.8634	0.8634	APC/POLK/MLH1/FOXO3/ERBB2/BAK1/PIK3R1	7
KEGG	hsa05330	Allograft rejection	5/652	38/8135	0.185	0.8634	0.8634	HLA-DPB1/HLA-DPA1/HLA-B/HLA-DOA/HLA-G	5
KEGG	hsa05225	Hepatocellular carcinoma	17/652	168/8135	0.1889	0.8634	0.8634	BCL2L1/ARID1B/APC/WNT1/GSTM4/ACTL6A/WNT16/POLK/E2F2/WNT2/SMARCE1/MTOR/SMARCA2/SMARCA4/BAK1/PIK3R1/E2F1	17
KEGG	hsa05160	Hepatitis C	16/652	157/8135	0.1903	0.8634	0.8634	CLDN5/IKBKB/OCLN/DDX58/EIF2AK1/CLDN14/RNASEL/E2F2/SOCS3/CLDN8/CLDN6/CLDN10/BAK1/PIK3R1/IFNA5/E2F1	16
KEGG	hsa04914	Progesterone-mediated oocyte maturation	11/652	102/8135	0.1925	0.8634	0.8634	CCNA1/PLK1/CDC25C/ANAPC5/ADCY3/CDK1/PKMYT1/HSP90AA1/PIK3R1/MAPK12/ANAPC7	11
KEGG	hsa04972	Pancreatic secretion	11/652	102/8135	0.1925	0.8634	0.8634	ITPR2/CPA2/CA2/ADCY3/CELA2B/PRSS2/ATP1A1/PRSS3/PLA2G10/SLC12A2/PLA2G1B	11
KEGG	hsa04917	Prolactin signaling pathway	8/652	70/8135	0.1959	0.8634	0.8634	SOCS7/SOCS3/FOXO3/GCK/LHCGR/STAT5A/PIK3R1/MAPK12	8
KEGG	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	8/652	70/8135	0.1959	0.8634	0.8634	NOD1/ATP6V1G3/IKBKB/CXCL1/CXCR1/ATP6V1B1/ATP6V1E1/MAPK12	8
KEGG	hsa00520	Amino sugar and nucleotide sugar metabolism	6/652	49/8135	0.196	0.8634	0.8634	CHIT1/PMM2/GALK2/CYB5RL/GCK/UGDH	6
KEGG	hsa04080	Neuroactive ligand-receptor interaction	33/652	353/8135	0.1973	0.8634	0.8634	EDN3/CTSG/UTS2/PTH2R/GLRA2/TACR3/MCHR1/KNG1/AVPR2/RLN3/F2/GPHA2/GALR3/CHRNA3/HTR1B/C3AR1/LTB4R2/F2RL3/RXFP3/PRSS2/GALR2/DRD2/PRSS3/ADCYAP1R1/GH2/GRM4/FPR2/LHCGR/GRM8/GABRR2/CYSLTR2/GCGR/GRP	33
KEGG	hsa05224	Breast cancer	15/652	147/8135	0.1985	0.8634	0.8634	APC/WNT1/FLT4/WNT16/POLK/E2F2/WNT2/MTOR/ERBB2/FGF3/FGF22/DLL3/BAK1/PIK3R1/E2F1	15
KEGG	hsa00513	Various types of N-glycan biosynthesis	5/652	39/8135	0.1993	0.8634	0.8634	MGAT2/B4GALNT4/STT3B/ALG13/MGAT4B	5
KEGG	hsa00591	Linoleic acid metabolism	4/652	29/8135	0.1993	0.8634	0.8634	PLA2G4C/PLA2G10/CYP2C9/PLA2G1B	4
KEGG	hsa04724	Glutamatergic synapse	12/652	114/8135	0.2011	0.8634	0.8634	ITPR2/PLA2G4C/PPP3R1/SHANK1/GLS/SLC1A3/HOMER2/ADCY3/GLUL/GRM4/GRM8/PPP3CA	12
KEGG	hsa05203	Viral carcinogenesis	20/652	204/8135	0.202	0.8634	0.8634	POLB/CCNA1/RBPJL/HDAC2/HPN/ACTN1/HLA-B/CCR4/GTF2H2/CDK1/GTF2H1/CDKN2B/SKP2/HLA-G/STAT5A/HDAC9/BAK1/JAK3/PIK3R1/HDAC3	20
KEGG	hsa05165	Human papillomavirus infection	31/652	331/8135	0.2033	0.8634	0.8634	CCNA1/RBPJL/HDAC2/ATR/APC/WNT1/ATP6V1G3/IKBKB/PARD6G/HLA-B/TNXB/PRKCI/WNT16/SLC9A3R1/ITGB3/COL4A6/ATP6V1B1/ATP6V1E1/WNT2/CRB3/COL9A3/MTOR/PARD6B/ITGA2B/HLA-G/ITGA7/COL6A6/BAK1/PIK3R1/IFNA5/E2F1	31
KEGG	hsa00510	N-Glycan biosynthesis	6/652	50/8135	0.2088	0.8634	0.8634	MGAT2/ST6GAL1/ALG8/STT3B/ALG13/MGAT4B	6
KEGG	hsa04141	Protein processing in endoplasmic reticulum	17/652	171/8135	0.2089	0.8634	0.8634	YOD1/UBQLN4/UBXN6/SAR1A/LMAN1L/DNAJC10/EIF2AK1/HSPH1/CKAP4/AMFR/HSPA1A/HSP90AA1/RAD23A/STT3B/BAK1/RNF5/NGLY1	17
KEGG	hsa04625	C-type lectin receptor signaling pathway	11/652	104/8135	0.2099	0.8634	0.8634	ITPR2/CCL22/PPP3R1/IKBKB/IL6/CALM3/PPP3CA/CLEC4D/BCL3/PIK3R1/MAPK12	11
KEGG	hsa00260	Glycine, serine and threonine metabolism	5/652	40/8135	0.2139	0.8686	0.8686	ALAS2/PSPH/GNMT/GCAT/SARDH	5
KEGG	hsa01523	Antifolate resistance	4/652	30/8135	0.2165	0.8686	0.8686	FOLR3/IKBKB/IL6/GART	4
KEGG	hsa05418	Fluid shear stress and atherosclerosis	14/652	139/8135	0.2227	0.8729	0.8729	MMP9/IL1R2/GSTM4/ACVR2B/IKBKB/GPC1/ITGB3/CALM3/HSP90AA1/ITGA2B/MAP2K5/TRPV4/PIK3R1/MAPK12	14
KEGG	hsa04213	Longevity regulating pathway - multiple species	7/652	62/8135	0.2262	0.8729	0.8729	HDAC2/AKT1S1/ADCY3/HSPA1A/MTOR/FOXO3/PIK3R1	7
KEGG	hsa00052	Galactose metabolism	4/652	31/8135	0.234	0.8729	0.8729	MGAM/AKR1B1/GCK/PFKM	4
KEGG	hsa05217	Basal cell carcinoma	7/652	63/8135	0.2384	0.8729	0.8729	APC/WNT1/WNT16/POLK/WNT2/PTCH2/BAK1	7
KEGG	hsa01232	Nucleotide metabolism	9/652	85/8135	0.2395	0.8729	0.8729	GMPR/HDDC2/DCTPP1/CDA/NT5M/GUK1/ADK/CANT1/CTPS2	9
KEGG	hsa04015	Rap1 signaling pathway	20/652	210/8135	0.2403	0.8729	0.8729	RAP1GAP/PARD6G/FLT4/PRKCI/ITGB3/F2RL3/KRIT1/ADCY3/FGFR3/CALM3/DRD2/NGFR/PARD6B/TLN1/FGF3/FGF22/ITGA2B/EFNA4/PIK3R1/MAPK12	20
KEGG	hsa05215	Prostate cancer	10/652	97/8135	0.2485	0.8729	0.8729	MMP9/IL1R2/IKBKB/E2F2/MTOR/ERBB2/HSP90AA1/NKX3-1/PIK3R1/E2F1	10
KEGG	hsa04114	Oocyte meiosis	13/652	131/8135	0.2499	0.8729	0.8729	ITPR2/PLK1/PPP3R1/CDC25C/ANAPC5/ADCY3/CDK1/PKMYT1/CAMK2G/CALM3/PPP3CA/MAPK12/ANAPC7	13
KEGG	hsa05210	Colorectal cancer	9/652	86/8135	0.2501	0.8729	0.8729	APPL1/AREG/APC/POLK/MSH2/MLH1/MTOR/BAK1/PIK3R1	9
KEGG	hsa03320	PPAR signaling pathway	8/652	75/8135	0.2509	0.8729	0.8729	APOA5/FADS2/PPARG/FABP5/RXRB/ACSL1/EHHADH/PPARD	8
KEGG	hsa05214	Glioma	8/652	75/8135	0.2509	0.8729	0.8729	POLK/E2F2/CAMK2G/CALM3/MTOR/BAK1/PIK3R1/E2F1	8
KEGG	hsa04215	Apoptosis - multiple species	4/652	32/8135	0.252	0.8729	0.8729	BCL2L1/BIRC6/NGFR/BAK1	4
KEGG	hsa01522	Endocrine resistance	10/652	98/8135	0.2585	0.8729	0.8729	MMP9/ADCY3/E2F2/MTOR/CYP2D6/ERBB2/DLL3/PIK3R1/MAPK12/E2F1	10
KEGG	hsa00071	Fatty acid degradation	5/652	43/8135	0.2596	0.8729	0.8729	CYP2U1/ACADS/ACSL1/EHHADH/ACADVL	5
KEGG	hsa05133	Pertussis	8/652	76/8135	0.2625	0.8729	0.8729	CXCL5/NOD1/C1QB/IL6/C1QA/C4BPA/CALM3/MAPK12	8
KEGG	hsa03460	Fanconi anemia pathway	6/652	54/8135	0.2627	0.8729	0.8729	ATR/REV3L/POLK/MLH1/RPA2/FANCL	6
KEGG	hsa04310	Wnt signaling pathway	16/652	167/8135	0.2632	0.8729	0.8729	ROCK2/APC/WNT1/PPP3R1/TLE6/WNT16/CAMK2G/RSPO4/SENP2/WNT2/CACYBP/LGR4/BAMBI/PPP3CA/DKK4/PPARD	16
KEGG	hsa04512	ECM-receptor interaction	9/652	88/8135	0.2717	0.8835	0.8835	TNXB/ITGB3/GP1BB/COL4A6/GP9/COL9A3/ITGA2B/ITGA7/COL6A6	9
KEGG	hsa05417	Lipid and atherosclerosis	20/652	215/8135	0.2743	0.8835	0.8835	MMP9/BCL2L1/ROCK2/MIB1/PPP3R1/CYP1A1/IKBKB/PPARG/CXCL1/RXRB/IL6/CAMK2G/CALM3/HSPA1A/HSP90AA1/PPP3CA/PIK3R1/MAPK12/IFNA5/CYP2C9	20
KEGG	hsa03430	Mismatch repair	3/652	23/8135	0.279	0.8835	0.8835	MSH2/MLH1/RPA2	3
KEGG	hsa04614	Renin-angiotensin system	3/652	23/8135	0.279	0.8835	0.8835	CTSG/MME/ACE	3
KEGG	hsa04211	Longevity regulating pathway	9/652	89/8135	0.2827	0.8835	0.8835	APPL1/AKT1S1/PPARG/ADIPOR1/ADCY3/MTOR/FOXO3/SESN1/PIK3R1	9
KEGG	hsa04668	TNF signaling pathway	11/652	112/8135	0.2851	0.8835	0.8835	MMP9/CXCL5/RPS6KA5/IKBKB/CXCL1/IL6/SOCS3/RIPK3/BCL3/PIK3R1/MAPK12	11
KEGG	hsa02010	ABC transporters	5/652	45/8135	0.2912	0.8835	0.8835	ABCA13/ABCB5/ABCB9/ABCA4/ABCB7	5
KEGG	hsa05410	Hypertrophic cardiomyopathy	9/652	90/8135	0.2939	0.8835	0.8835	ITGB3/IL6/CACNG2/ACE/ITGA2B/CACNB2/SLC8A3/ITGA7/TPM4	9
KEGG	hsa05142	Chagas disease	10/652	102/8135	0.3	0.8835	0.8835	IKBKB/KNG1/C1QB/IL6/C1QA/IFNGR1/ACE/GNAL/PIK3R1/MAPK12	10
KEGG	hsa04670	Leukocyte transendothelial migration	11/652	114/8135	0.305	0.8835	0.8835	MMP9/ROCK2/ACTN1/CLDN5/OCLN/CLDN14/CLDN8/CLDN6/CLDN10/PIK3R1/MAPK12	11
KEGG	hsa01212	Fatty acid metabolism	6/652	57/8135	0.3052	0.8835	0.8835	FADS2/ACADS/ACSL1/EHHADH/ACADVL/ELOVL2	6
KEGG	hsa04930	Type II diabetes mellitus	5/652	46/8135	0.3073	0.8835	0.8835	IKBKB/SOCS3/MTOR/GCK/PIK3R1	5
KEGG	hsa04915	Estrogen signaling pathway	13/652	138/8135	0.3125	0.8835	0.8835	MMP9/ITPR2/FKBP5/FKBP4/ADCY3/CALM3/HSPA1A/HSP90AA1/NCOA2/EBAG9/KRT13/KRT19/PIK3R1	13
KEGG	hsa00240	Pyrimidine metabolism	6/652	58/8135	0.3197	0.8835	0.8835	HDDC2/DCTPP1/CDA/NT5M/CANT1/CTPS2	6
KEGG	hsa05162	Measles	13/652	139/8135	0.3217	0.8835	0.8835	BCL2L1/IKBKB/DDX58/EIF2AK1/CD46/IL6/HSPA1A/FCGR2B/STAT5A/BAK1/JAK3/PIK3R1/IFNA5	13
KEGG	hsa04973	Carbohydrate digestion and absorption	5/652	47/8135	0.3235	0.8835	0.8835	MGAM/SLC2A5/SLC5A1/ATP1A1/PIK3R1	5
KEGG	hsa00500	Starch and sucrose metabolism	4/652	36/8135	0.3258	0.8835	0.8835	MGAM/PYGB/GCK/GYS2	4
KEGG	hsa00512	Mucin type O-glycan biosynthesis	4/652	36/8135	0.3258	0.8835	0.8835	B4GALT5/GALNT9/GALNT6/B3GNT3	4
KEGG	hsa04970	Salivary secretion	9/652	93/8135	0.3279	0.8835	0.8835	CAMP/ITPR2/ADCY3/CALM3/AQP5/ATP1A1/MUC7/PRB1/SLC12A2	9
KEGG	hsa05323	Rheumatoid arthritis	9/652	93/8135	0.3279	0.8835	0.8835	HLA-DPB1/CXCL5/ATP6V1G3/HLA-DPA1/CXCL1/IL6/HLA-DOA/ATP6V1B1/ATP6V1E1	9
KEGG	hsa04380	Osteoclast differentiation	12/652	128/8135	0.3285	0.8835	0.8835	PPP3R1/IKBKB/PPARG/ITGB3/LILRA3/IFNGR1/FCGR2B/SOCS3/FCGR3B/PPP3CA/PIK3R1/MAPK12	12
KEGG	hsa05170	Human immunodeficiency virus 1 infection	19/652	212/8135	0.3389	0.8835	0.8835	ITPR2/BCL2L1/ATR/PPP3R1/IKBKB/LIMK2/AP1M2/HLA-B/CDC25C/CDK1/CALM3/MTOR/HLA-G/APOBEC3B/PPP3CA/BAK1/PIK3R1/MAPK12/IFNA5	19
KEGG	hsa05207	Chemical carcinogenesis - receptor activation	19/652	212/8135	0.3389	0.8835	0.8835	KLF5/PAQR8/WNT1/GSTM4/CYP1A1/CHRNA3/RXRB/ADCY3/EPHX3/MTOR/HSP90AA1/FGF3/FGF22/DLL3/STAT5A/MIRLET7D/PIK3R1/PTGES3/E2F1	19
KEGG	hsa00730	Thiamine metabolism	2/652	15/8135	0.3412	0.8835	0.8835	ALPL/NFS1	2
KEGG	hsa00250	Alanine, aspartate and glutamate metabolism	4/652	37/8135	0.3445	0.8835	0.8835	GLS/GLUL/ABAT/GOT1L1	4
KEGG	hsa01250	Biosynthesis of nucleotide sugars	4/652	37/8135	0.3445	0.8835	0.8835	PMM2/GALK2/GCK/UGDH	4
KEGG	hsa05143	African trypanosomiasis	4/652	37/8135	0.3445	0.8835	0.8835	HBB/KNG1/IL6/NPPA	4
KEGG	hsa05416	Viral myocarditis	6/652	60/8135	0.3488	0.8835	0.8835	HLA-DPB1/HLA-DPA1/HLA-B/HLA-DOA/HLA-G/EIF4G3	6
KEGG	hsa04120	Ubiquitin mediated proteolysis	13/652	142/8135	0.3499	0.8835	0.8835	UBE4A/BIRC6/UBE2QL1/FBXW8/ANAPC5/CDC34/UBE2L3/SKP2/SOCS3/UBE2H/FANCL/HUWE1/ANAPC7	13
KEGG	hsa04613	Neutrophil extracellular trap formation	17/652	190/8135	0.3536	0.8835	0.8835	CAMP/ELANE/AZU1/CR1L/MPO/CTSG/HDAC2/ITGB3/AQP9/MTOR/FPR2/ITGA2B/FCGR3B/HDAC9/PIK3R1/MAPK12/HDAC3	17
KEGG	hsa05218	Melanoma	7/652	72/8135	0.355	0.8835	0.8835	POLK/E2F2/FGF3/FGF22/BAK1/PIK3R1/E2F1	7
KEGG	hsa00565	Ether lipid metabolism	5/652	49/8135	0.3561	0.8835	0.8835	PLA2G4C/PLD4/GDPD1/PLA2G10/PLA2G1B	5
KEGG	hsa04672	Intestinal immune network for IgA production	5/652	49/8135	0.3561	0.8835	0.8835	HLA-DPB1/HLA-DPA1/IL6/HLA-DOA/PIGR	5
KEGG	hsa04020	Calcium signaling pathway	21/652	240/8135	0.3692	0.8968	0.8968	ITPR2/TACR3/PPP3R1/CACNA1H/FLT4/NTRK1/LTB4R2/PHKB/RYR1/ADCY3/CAMK2G/FGFR3/CALM3/GNAL/ERBB2/FGF3/LHCGR/FGF22/SLC8A3/CYSLTR2/PPP3CA	21
KEGG	hsa04150	mTOR signaling pathway	14/652	156/8135	0.3695	0.8968	0.8968	WNT1/STRADB/ATP6V1G3/AKT1S1/IKBKB/WNT16/ATP6V1B1/ATP6V1E1/WNT2/SKP2/MTOR/GRB10/SLC7A5/PIK3R1	14
KEGG	hsa05110	Vibrio cholerae infection	5/652	50/8135	0.3725	0.8968	0.8968	ATP6V1G3/ADCY3/ATP6V1B1/ATP6V1E1/SLC12A2	5
KEGG	hsa05144	Malaria	5/652	50/8135	0.3725	0.8968	0.8968	HBB/GYPB/CR1L/GYPA/IL6	5
KEGG	hsa04066	HIF-1 signaling pathway	10/652	109/8135	0.376	0.8984	0.8984	TFRC/IL6/CAMK2G/IFNGR1/NPPA/LDHC/MTOR/ERBB2/PFKM/PIK3R1	10
KEGG	hsa04530	Tight junction	15/652	169/8135	0.3787	0.8984	0.8984	ROCK2/ACTN1/CLDN5/OCLN/PARD6G/CLDN14/PRKCI/SLC9A3R1/CRB3/ERBB2/PARD6B/ACTR3B/CLDN8/CLDN6/CLDN10	15
KEGG	hsa04925	Aldosterone synthesis and secretion	9/652	98/8135	0.386	0.9091	0.9091	ITPR2/CACNA1H/ADCY3/CAMK2G/CALM3/NPR1/ATP1A1/NPPA/ATF1	9
KEGG	hsa00650	Butanoate metabolism	3/652	28/8135	0.3918	0.9122	0.9122	ACADS/ABAT/EHHADH	3
KEGG	hsa04623	Cytosolic DNA-sensing pathway	6/652	63/8135	0.3929	0.9122	0.9122	IKBKB/DDX58/IL6/POLR3A/RIPK3/IFNA5	6
KEGG	hsa05171	Coronavirus disease - COVID-19	20/652	232/8135	0.4002	0.9224	0.9224	RPS4Y1/RPS27/IKBKB/F2/DDX58/RPL36AL/C3AR1/C1QB/IL6/RPS3A/C1QA/RPS15A/ACE/RPS11/RPL15/RPS15/RPL21/PIK3R1/MAPK12/IFNA5	20
KEGG	hsa04910	Insulin signaling pathway	12/652	137/8135	0.4181	0.9362	0.9362	PYGB/IKBKB/PRKCI/PHKB/CALM3/SOCS3/MTOR/GCK/GYS2/PTPN1/PIK3R1/PPP1R3B	12
KEGG	hsa03440	Homologous recombination	4/652	41/8135	0.4193	0.9362	0.9362	RAD50/RPA2/BRCC3/TOPBP1	4
KEGG	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	8/652	89/8135	0.4219	0.9362	0.9362	PPP3R1/IKBKB/IFNGR1/MTOR/PPP3CA/PDCD1/PIK3R1/MAPK12	8
KEGG	hsa05140	Leishmaniasis	7/652	77/8135	0.4224	0.9362	0.9362	HLA-DPB1/CR1L/HLA-DPA1/HLA-DOA/IFNGR1/FCGR3B/MAPK12	7
KEGG	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	7/652	77/8135	0.4224	0.9362	0.9362	CDH2/ITGB3/CACNG2/ITGA2B/CACNB2/SLC8A3/ITGA7	7
KEGG	hsa04630	JAK-STAT signaling pathway	14/652	162/8135	0.4249	0.9362	0.9362	BCL2L1/SOCS7/IL7/IL6/IL20RA/IFNGR1/SOCS3/MTOR/GH2/IL22RA1/STAT5A/JAK3/PIK3R1/IFNA5	14
KEGG	hsa00061	Fatty acid biosynthesis	2/652	18/8135	0.4292	0.9362	0.9362	OLAH/ACSL1	2
KEGG	hsa00511	Other glycan degradation	2/652	18/8135	0.4292	0.9362	0.9362	NEU2/AGA	2
KEGG	hsa00630	Glyoxylate and dicarboxylate metabolism	3/652	30/8135	0.436	0.9405	0.9405	PCCA/GLUL/MCEE	3
KEGG	hsa00970	Aminoacyl-tRNA biosynthesis	6/652	66/8135	0.4369	0.9405	0.9405	NARS2/GATC/FARS2/IARS2/QRSL1/DARS2	6
KEGG	hsa01521	EGFR tyrosine kinase inhibitor resistance	7/652	79/8135	0.4492	0.9604	0.9604	BCL2L1/IL6/FGFR3/MTOR/FOXO3/ERBB2/PIK3R1	7
KEGG	hsa00531	Glycosaminoglycan degradation	2/652	19/8135	0.4572	0.9712	0.9712	HYAL4/SGSH	2
KEGG	hsa04936	Alcoholic liver disease	12/652	142/8135	0.4683	0.9753	0.9753	IKBKB/CXCL1/C3AR1/C1QB/IL6/ADIPOR1/C1QA/FOXO3/ACADVL/IL17RC/MAPK12/IFNA5	12
KEGG	hsa04151	PI3K-Akt signaling pathway	29/652	354/8135	0.4796	0.9753	0.9753	BCL2L1/AREG/IKBKB/PHLPP2/TNXB/IL7/FLT4/NTRK1/ITGB3/IL6/COL4A6/FGFR3/COL9A3/MTOR/NGFR/GH2/FOXO3/ERBB2/HSP90AA1/FGF3/FGF22/ITGA2B/GYS2/ITGA7/COL6A6/EFNA4/JAK3/PIK3R1/IFNA5	29
KEGG	hsa04920	Adipocytokine signaling pathway	6/652	69/8135	0.4804	0.9753	0.9753	IKBKB/RXRB/ADIPOR1/ACSL1/SOCS3/MTOR	6
KEGG	hsa05031	Amphetamine addiction	6/652	69/8135	0.4804	0.9753	0.9753	HDAC2/PPP3R1/SLC18A1/CAMK2G/CALM3/PPP3CA	6
KEGG	hsa00670	One carbon pool by folate	2/652	20/8135	0.4844	0.9753	0.9753	MTR/GART	2
KEGG	hsa05134	Legionellosis	5/652	57/8135	0.4856	0.9753	0.9753	CR1L/SAR1A/CXCL1/IL6/HSPA1A	5
KEGG	hsa04722	Neurotrophin signaling pathway	10/652	119/8135	0.4864	0.9753	0.9753	RPS6KA5/IKBKB/NTRK1/CAMK2G/CALM3/NGFR/FOXO3/MAP2K5/PIK3R1/MAPK12	10
KEGG	hsa03022	Basal transcription factors	4/652	45/8135	0.4919	0.9753	0.9753	GTF2H2/GTF2H1/TAF4/TAF5	4
KEGG	hsa04142	Lysosome	11/652	132/8135	0.4926	0.9753	0.9753	CTSG/DMXL1/HYAL4/AP3M1/AP1M2/SGSH/ABCB9/ARSA/AP3S2/WDR7/AGA	11
KEGG	hsa04622	RIG-I-like receptor signaling pathway	6/652	70/8135	0.4946	0.9753	0.9753	IKBKB/ATG12/DDX58/SIKE1/MAPK12/IFNA5	6
KEGG	hsa04152	AMPK signaling pathway	10/652	120/8135	0.4973	0.9753	0.9753	CCNA1/STRADB/AKT1S1/PPARG/ADIPOR1/MTOR/FOXO3/GYS2/PFKM/PIK3R1	10
KEGG	hsa04130	SNARE interactions in vesicular transport	3/652	33/8135	0.4998	0.9753	0.9753	STX8/STX18/YKT6	3
KEGG	hsa04060	Cytokine-cytokine receptor interaction	24/652	295/8135	0.5011	0.9753	0.9753	CXCL5/CCL22/IL1R2/ACVR2B/IL7/CXCL1/CCR4/IL6/EBI3/CXCR1/IL20RA/PF4V1/TNFRSF18/IFNGR1/IL1RAP/NGFR/GH2/IL22RA1/BMP8B/IL17RC/CCL7/IFNA5/CCL24/IL34	24
KEGG	hsa04931	Insulin resistance	9/652	108/8135	0.5025	0.9753	0.9753	PYGB/IKBKB/IL6/SOCS3/MTOR/GYS2/PTPN1/PIK3R1/PPP1R3B	9
KEGG	hsa05164	Influenza A	14/652	171/8135	0.5079	0.9753	0.9753	HLA-DPB1/IKBKB/HLA-DPA1/DDX58/IL6/RNASEL/HLA-DOA/PRSS2/IFNGR1/PRSS3/SOCS3/BAK1/PIK3R1/IFNA5	14
KEGG	hsa05414	Dilated cardiomyopathy	8/652	96/8135	0.5083	0.9753	0.9753	ITGB3/ADCY3/CACNG2/ITGA2B/CACNB2/SLC8A3/ITGA7/TPM4	8
KEGG	hsa00770	Pantothenate and CoA biosynthesis	2/652	21/8135	0.5107	0.9753	0.9753	CSAD/VNN1	2
KEGG	hsa04270	Vascular smooth muscle contraction	11/652	134/8135	0.5132	0.9753	0.9753	ITPR2/EDN3/ROCK2/PLA2G4C/RAMP1/ADCY3/CALM3/NPR1/NPPA/PLA2G10/PLA2G1B	11
KEGG	hsa04370	VEGF signaling pathway	5/652	59/8135	0.5168	0.9764	0.9764	PLA2G4C/PPP3R1/PPP3CA/PIK3R1/MAPK12	5
KEGG	hsa04137	Mitophagy - animal	6/652	72/8135	0.5227	0.9798	0.9798	BCL2L1/MAP1LC3A/MFN1/FOXO3/BNIP3L/E2F1	6
KEGG	hsa03420	Nucleotide excision repair	4/652	47/8135	0.5268	0.9798	0.9798	GTF2H2/GTF2H1/RPA2/RAD23A	4
KEGG	hsa04072	Phospholipase D signaling pathway	12/652	148/8135	0.5276	0.9798	0.9798	PLA2G4C/AVPR2/FCER1A/F2/AGPAT1/ADCY3/CXCR1/AGPAT5/MTOR/GRM4/GRM8/PIK3R1	12
KEGG	hsa00900	Terpenoid backbone biosynthesis	2/652	22/8135	0.5361	0.9828	0.9828	ICMT/PCYOX1	2
KEGG	hsa04115	p53 signaling pathway	6/652	73/8135	0.5365	0.9828	0.9828	BCL2L1/ATR/ZMAT3/CDK1/GTSE1/SESN1	6
KEGG	hsa05163	Human cytomegalovirus infection	18/652	225/8135	0.5398	0.9828	0.9828	ITPR2/ROCK2/PPP3R1/IKBKB/HLA-B/ITGB3/IL6/ADCY3/E2F2/CALM3/MTOR/HLA-G/PPP3CA/BAK1/PIK3R1/MAPK12/IFNA5/E2F1	18
KEGG	hsa04261	Adrenergic signaling in cardiomyocytes	12/652	150/8135	0.5469	0.9828	0.9828	MYL4/RPS6KA5/SCN5A/ADCY3/CACNG2/CAMK2G/CALM3/ATP1A1/CACNB2/SLC8A3/TPM4/MAPK12	12
KEGG	hsa00561	Glycerolipid metabolism	5/652	61/8135	0.5471	0.9828	0.9828	LIPF/AGPAT1/AKR1B1/AGPAT5/MOGAT3	5
KEGG	hsa00350	Tyrosine metabolism	3/652	36/8135	0.5597	0.9828	0.9828	TYR/FAHD1/GOT1L1	3
KEGG	hsa01230	Biosynthesis of amino acids	6/652	75/8135	0.5636	0.9828	0.9828	ARG1/PSPH/MTR/GLUL/GOT1L1/PFKM	6
KEGG	hsa04918	Thyroid hormone synthesis	6/652	75/8135	0.5636	0.9828	0.9828	ITPR2/TTF1/ADCY3/ATP1A1/TG/TTF2	6
KEGG	hsa00920	Sulfur metabolism	1/652	10/8135	0.5665	0.9828	0.9828	SELENBP1	1
KEGG	hsa04916	Melanogenesis	8/652	101/8135	0.5675	0.9828	0.9828	WNT1/WNT16/ADCY3/CAMK2G/ASIP/CALM3/TYR/WNT2	8
KEGG	hsa03250	Viral life cycle - HIV-1	5/652	63/8135	0.5764	0.9828	0.9828	PDCD6IP/SERINC3/FURIN/TNPO3/APOBEC3B	5
KEGG	hsa04979	Cholesterol metabolism	4/652	50/8135	0.5768	0.9828	0.9828	ANGPTL3/OSBPL5/SOAT1/LPA	4
KEGG	hsa04960	Aldosterone-regulated sodium reabsorption	3/652	37/8135	0.5787	0.9828	0.9828	ATP1A1/SCNN1B/PIK3R1	3
KEGG	hsa04062	Chemokine signaling pathway	15/652	192/8135	0.581	0.9828	0.9828	CXCL5/CCL22/ROCK2/IKBKB/CXCL1/CCR4/ADCY3/CXCR1/PF4V1/FOXO3/CCL7/GRK1/JAK3/PIK3R1/CCL24	15
KEGG	hsa04010	MAPK signaling pathway	23/652	294/8135	0.5814	0.9828	0.9828	AREG/PLA2G4C/RPS6KA5/PPP3R1/IKBKB/CACNA1H/FLT4/NTRK1/CACNG2/FGFR3/DAXX/HSPA1A/MAPK8IP2/IL1RAP/NGFR/ERBB2/FGF3/FGF22/CACNB2/MAP2K5/EFNA4/PPP3CA/MAPK12	23
KEGG	hsa05205	Proteoglycans in cancer	16/652	205/8135	0.5828	0.9828	0.9828	MMP9/ITPR2/ROCK2/ANK1/WNT1/GPC3/GPC1/WNT16/ITGB3/CAMK2G/WNT2/MTOR/ERBB2/TWIST2/PIK3R1/MAPK12	16
KEGG	hsa04140	Autophagy - animal	11/652	141/8135	0.5831	0.9828	0.9828	BCL2L1/AKT1S1/ATG12/MAP1LC3A/PIK3R4/DAPK3/MTOR/ATG4A/SH3GLB1/ATG10/PIK3R1	11
KEGG	hsa00270	Cysteine and methionine metabolism	4/652	51/8135	0.5928	0.9828	0.9828	MTR/LDHC/GOT1L1/DNMT3A	4
KEGG	hsa04913	Ovarian steroidogenesis	4/652	51/8135	0.5928	0.9828	0.9828	PLA2G4C/CYP1A1/ADCY3/LHCGR	4
KEGG	hsa04934	Cushing syndrome	12/652	155/8135	0.5939	0.9828	0.9828	ITPR2/APC/WNT1/CACNA1H/WNT16/ADCY3/E2F2/CAMK2G/KCNA4/WNT2/CDKN2B/E2F1	12
KEGG	hsa04714	Thermogenesis	18/652	232/8135	0.594	0.9828	0.9828	NDUFA12/NDUFB2/ARID1B/AKT1S1/ACTL6A/PPARG/ADCY3/COX18/KDM1A/ACSL1/NPR1/SMARCE1/NPPA/MTOR/BMP8B/SMARCA2/SMARCA4/MAPK12	18
KEGG	hsa05340	Primary immunodeficiency	3/652	38/8135	0.5971	0.9828	0.9828	DCLRE1C/RFXAP/JAK3	3
KEGG	hsa00130	Ubiquinone and other terpenoid-quinone biosynthesis	1/652	11/8135	0.6013	0.9828	0.9828	COQ6	1
KEGG	hsa04721	Synaptic vesicle cycle	6/652	78/8135	0.6028	0.9828	0.9828	ATP6V1G3/SLC18A1/SLC1A3/ATP6V1B1/ATP6V1E1/SLC6A7	6
KEGG	hsa05321	Inflammatory bowel disease	5/652	65/8135	0.6048	0.9828	0.9828	HLA-DPB1/HLA-DPA1/IL6/HLA-DOA/IFNGR1	5
KEGG	hsa04068	FoxO signaling pathway	10/652	131/8135	0.6116	0.989	0.989	PLK1/IKBKB/ATG12/HOMER2/IL6/CDKN2B/SKP2/FOXO3/PIK3R1/MAPK12	10
KEGG	hsa05130	Pathogenic Escherichia coli infection	15/652	197/8135	0.6219	0.9959	0.9959	BAIAP2L1/ROCK2/CLDN5/IKBKB/OCLN/F2/CLDN14/SLC9A3R1/IL6/ACTR3B/CLDN8/CLDN6/CLDN10/BAK1/MAPK12	15
KEGG	hsa04935	Growth hormone synthesis, secretion and action	9/652	119/8135	0.6221	0.9959	0.9959	ITPR2/POU1F1/ADCY3/SOCS3/MTOR/GH2/STAT5A/PIK3R1/MAPK12	9
KEGG	hsa00563	Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	2/652	26/8135	0.6284	0.9962	0.9962	PIGL/PIGP	2
KEGG	hsa00790	Folate biosynthesis	2/652	26/8135	0.6284	0.9962	0.9962	ALPL/AKR1B1	2
KEGG	hsa04720	Long-term potentiation	5/652	67/8135	0.632	0.9971	0.9971	ITPR2/PPP3R1/CAMK2G/CALM3/PPP3CA	5
KEGG	hsa04919	Thyroid hormone signaling pathway	9/652	121/8135	0.6422	1	1	HDAC2/ITGB3/RXRB/ATP1A1/MTOR/NCOA2/PFKM/PIK3R1/HDAC3	9
KEGG	hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	2/652	27/8135	0.6491	1	1	B3GNT5/B3GNT3	2
KEGG	hsa01040	Biosynthesis of unsaturated fatty acids	2/652	27/8135	0.6491	1	1	FADS2/ELOVL2	2
KEGG	hsa04216	Ferroptosis	3/652	41/8135	0.6493	1	1	MAP1LC3A/TFRC/ACSL1	3
KEGG	hsa04662	B cell receptor signaling pathway	6/652	82/8135	0.6519	1	1	PPP3R1/IKBKB/LILRA3/FCGR2B/PPP3CA/PIK3R1	6
KEGG	hsa05161	Hepatitis B	12/652	162/8135	0.6557	1	1	MMP9/CCNA1/IKBKB/DDX58/IL6/E2F2/STAT5A/JAK3/PIK3R1/MAPK12/IFNA5/E2F1	12
KEGG	hsa00380	Tryptophan metabolism	3/652	42/8135	0.6655	1	1	CYP1A1/DHTKD1/EHHADH	3
KEGG	hsa04923	Regulation of lipolysis in adipocytes	4/652	56/8135	0.6671	1	1	ADCY3/NPR1/NPPA/PIK3R1	4
KEGG	hsa04666	Fc gamma R-mediated phagocytosis	7/652	97/8135	0.6692	1	1	PLA2G4C/LIMK2/AMPH/FCGR2B/ACTR3B/FCGR3B/PIK3R1	7
KEGG	hsa04713	Circadian entrainment	7/652	97/8135	0.6692	1	1	RPS6KA5/CACNA1H/RYR1/ADCY3/CAMK2G/CALM3/ADCYAP1R1	7
KEGG	hsa00564	Glycerophospholipid metabolism	7/652	98/8135	0.6798	1	1	PLA2G4C/PLD4/PGS1/AGPAT1/AGPAT5/PLA2G10/PLA2G1B	7
KEGG	hsa04810	Regulation of actin cytoskeleton	16/652	218/8135	0.6818	1	1	ROCK2/APC/ACTN1/KNG1/LIMK2/F2/TMSB4Y/ITGB3/ITGAD/FGFR3/FGF3/ACTR3B/FGF22/ITGA2B/ITGA7/PIK3R1	16
KEGG	hsa05145	Toxoplasmosis	8/652	112/8135	0.6847	1	1	HLA-DPB1/BCL2L1/IKBKB/HLA-DPA1/HLA-DOA/HSPA1A/IFNGR1/MAPK12	8
KEGG	hsa04012	ErbB signaling pathway	6/652	85/8135	0.6862	1	1	AREG/CAMK2G/MTOR/ERBB2/STAT5A/PIK3R1	6
KEGG	hsa04744	Phototransduction	2/652	29/8135	0.6878	1	1	CALM3/GRK1	2
KEGG	hsa04725	Cholinergic synapse	8/652	113/8135	0.6943	1	1	ITPR2/CHRNA3/ADCY3/CAMK2G/KCNJ2/KCNJ12/KCNQ4/PIK3R1	8
KEGG	hsa04742	Taste transduction	6/652	86/8135	0.6971	1	1	HTR1B/SCNN1B/HTR3C/GRM4/TAS2R3/KCNK5	6
KEGG	hsa05131	Shigellosis	18/652	247/8135	0.6999	1	1	ITPR2/BCL2L1/ROCK2/NOD1/RPS6KA5/ACTN1/AKT1S1/IKBKB/ATG12/MAP1LC3A/PIK3R4/PPID/MTOR/FOXO3/TLN1/ACTR3B/PIK3R1/MAPK12	18
KEGG	hsa04330	Notch signaling pathway	4/652	59/8135	0.707	1	1	RBPJL/HDAC2/TLE6/DLL3	4
KEGG	hsa00230	Purine metabolism	9/652	128/8135	0.7076	1	1	GMPR/HDDC2/ADCY3/NPR1/NT5M/GUK1/ADK/CANT1/GART	9
KEGG	hsa04260	Cardiac muscle contraction	6/652	87/8135	0.7078	1	1	MYL4/CACNG2/ATP1A1/CACNB2/SLC8A3/TPM4	6
KEGG	hsa00604	Glycosphingolipid biosynthesis - ganglio series	1/652	15/8135	0.7147	1	1	SLC33A1	1
KEGG	hsa04390	Hippo signaling pathway	11/652	157/8135	0.7234	1	1	AREG/APC/WNT1/PARD6G/PRKCI/WNT16/WNT2/SMAD1/PARD6B/BMP8B/SOX2	11
KEGG	hsa04976	Bile secretion	6/652	89/8135	0.7283	1	1	CA2/SLC22A7/ADCY3/SLC5A1/AQP9/ATP1A1	6
KEGG	hsa03010	Ribosome	11/652	158/8135	0.731	1	1	RPS4Y1/RPS27/MRPL34/RPL36AL/RPS3A/RPS15A/RPS11/RPL15/RPS15/RPL21/MRPL14	11
KEGG	hsa04650	Natural killer cell mediated cytotoxicity	9/652	131/8135	0.7331	1	1	PPP3R1/HLA-B/MICA/IFNGR1/HLA-G/FCGR3B/PPP3CA/PIK3R1/IFNA5	9
KEGG	hsa00360	Phenylalanine metabolism	1/652	16/8135	0.7376	1	1	GOT1L1	1
KEGG	hsa00430	Taurine and hypotaurine metabolism	1/652	16/8135	0.7376	1	1	CSAD	1
KEGG	hsa04217	Necroptosis	11/652	159/8135	0.7385	1	1	PLA2G4C/PYGB/CAMK2G/GLUL/PPID/IFNGR1/HSP90AA1/STAT5A/RIPK3/JAK3/IFNA5	11
KEGG	hsa00514	Other types of O-glycan biosynthesis	3/652	47/8135	0.7386	1	1	ST6GAL1/GALNT9/GALNT6	3
KEGG	hsa03040	Spliceosome	10/652	147/8135	0.7511	1	1	CDC5L/ACIN1/DHX16/DDX46/BUD31/HNRNPU/PRPF8/THOC2/HSPA1A/ZMAT2	10
KEGG	hsa03410	Base excision repair	2/652	33/8135	0.7546	1	1	POLB/PARP4	2
KEGG	hsa00120	Primary bile acid biosynthesis	1/652	17/8135	0.7587	1	1	CH25H	1
KEGG	hsa00450	Selenocompound metabolism	1/652	17/8135	0.7587	1	1	MTR	1
KEGG	hsa04912	GnRH signaling pathway	6/652	93/8135	0.7664	1	1	ITPR2/PLA2G4C/ADCY3/CAMK2G/CALM3/MAPK12	6
KEGG	hsa00040	Pentose and glucuronate interconversions	2/652	34/8135	0.7692	1	1	AKR1B1/UGDH	2
KEGG	hsa03020	RNA polymerase	2/652	34/8135	0.7692	1	1	CD3EAP/POLR3A	2
KEGG	hsa04014	Ras signaling pathway	16/652	232/8135	0.772	1	1	BCL2L1/PLA2G4C/IKBKB/FLT4/NTRK1/KSR2/FGFR3/CALM3/NGFR/FGF3/RAB5B/FGF22/PLA2G10/EFNA4/PIK3R1/PLA2G1B	16
KEGG	hsa04210	Apoptosis	9/652	136/8135	0.7723	1	1	ITPR2/BCL2L1/SPTA1/PARP4/IKBKB/NTRK1/DAXX/BAK1/PIK3R1	9
KEGG	hsa05322	Systemic lupus erythematosus	9/652	136/8135	0.7723	1	1	HLA-DPB1/ELANE/CTSG/ACTN1/HLA-DPA1/C1QB/C1QA/HLA-DOA/FCGR3B	9
KEGG	hsa04350	TGF-beta signaling pathway	6/652	94/8135	0.7752	1	1	ACVR2B/HAMP/CDKN2B/SMAD1/BMP8B/BAMBI	6
KEGG	hsa04927	Cortisol synthesis and secretion	4/652	65/8135	0.7761	1	1	ITPR2/CACNA1H/ADCY3/KCNA4	4
KEGG	hsa04024	cAMP signaling pathway	15/652	221/8135	0.7869	1	1	EDN3/ROCK2/GPHA2/HTR1B/ADCY3/SUCNR1/CAMK2G/CALM3/NPR1/ATP1A1/NPPA/DRD2/ADCYAP1R1/LHCGR/PIK3R1	15
KEGG	hsa00330	Arginine and proline metabolism	3/652	51/8135	0.7875	1	1	ARG1/SMOX/GOT1L1	3
KEGG	hsa05022	Pathways of neurodegeneration - multiple diseases	34/652	476/8135	0.7886	1	1	ITPR2/BCL2L1/NDUFA12/SNCA/NDUFB2/APC/WNT1/PPP3R1/PSMD12/ATXN2/MAP1LC3A/PIK3R4/WNT16/RYR1/PARK7/NEFH/DCTN6/IL6/CAMK2G/CALM3/MFN1/PPID/KLC4/DNAH17/DAXX/WNT2/UBE2L3/DNAH10/DCTN5/MTOR/PPP3CA/BAK1/MAPK12/DKK4	34
KEGG	hsa01240	Biosynthesis of cofactors	10/652	153/8135	0.7934	1	1	ALAS2/ALPL/FECH/PMM2/LIAS/QPRT/NFS1/UGDH/COQ6/CTPS2	10
KEGG	hsa04022	cGMP-PKG signaling pathway	11/652	167/8135	0.7936	1	1	ITPR2/ROCK2/PPP3R1/KNG1/ADCY3/CALM3/NPR1/ATP1A1/NPPA/SLC8A3/PPP3CA	11
KEGG	hsa04371	Apelin signaling pathway	9/652	139/8135	0.7937	1	1	ITPR2/MYL4/MAP1LC3A/PIK3R4/RYR1/ADCY3/CALM3/MTOR/SLC8A3	9
KEGG	hsa01210	2-Oxocarboxylic acid metabolism	1/652	19/8135	0.7959	1	1	GOT1L1	1
KEGG	hsa00760	Nicotinate and nicotinamide metabolism	2/652	36/8135	0.7962	1	1	QPRT/NT5M	2
KEGG	hsa03030	DNA replication	2/652	36/8135	0.7962	1	1	RPA2/RNASEH2A	2
KEGG	hsa00600	Sphingolipid metabolism	3/652	52/8135	0.7984	1	1	ARSA/KDSR/NEU2	3
KEGG	hsa04664	Fc epsilon RI signaling pathway	4/652	68/8135	0.8055	1	1	PLA2G4C/FCER1A/PIK3R1/MAPK12	4
KEGG	hsa05012	Parkinson disease	18/652	266/8135	0.808	1	1	ITPR2/BCL2L1/NDUFA12/SNCA/NDUFB2/SLC18A1/PSMD12/SLC39A5/SLC39A2/PARK7/CAMK2G/CALM3/MFN1/KLC4/DAXX/UBE2L3/GNAL/DRD2	18
KEGG	hsa00100	Steroid biosynthesis	1/652	20/8135	0.8123	1	1	SOAT1	1
KEGG	hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	1/652	20/8135	0.8123	1	1	XYLT1	1
KEGG	hsa05017	Spinocerebellar ataxia	9/652	143/8135	0.8199	1	1	ITPR2/RBPJL/PSMD12/ATXN2/PIK3R4/RYR1/MTOR/OMA1/PIK3R1	9
KEGG	hsa01200	Carbon metabolism	7/652	115/8135	0.8254	1	1	PSPH/PCCA/ACADS/GCK/GOT1L1/MCEE/PFKM	7
KEGG	hsa04726	Serotonergic synapse	7/652	115/8135	0.8254	1	1	ITPR2/PLA2G4C/SLC18A1/HTR1B/CYP2D6/HTR3C/CYP2C9	7
KEGG	hsa04510	Focal adhesion	13/652	201/8135	0.8283	1	1	ROCK2/ACTN1/TNXB/FLT4/ITGB3/COL4A6/COL9A3/ERBB2/TLN1/ITGA2B/ITGA7/COL6A6/PIK3R1	13
KEGG	hsa04911	Insulin secretion	5/652	86/8135	0.8298	1	1	ADCY3/CAMK2G/ATP1A1/ADCYAP1R1/GCK	5
KEGG	hsa04728	Dopaminergic synapse	8/652	132/8135	0.8407	1	1	ITPR2/SLC18A1/CAMK2G/CALM3/GNAL/DRD2/PPP3CA/MAPK12	8
KEGG	hsa04540	Gap junction	5/652	88/8135	0.8445	1	1	ITPR2/ADCY3/CDK1/DRD2/MAP2K5	5
KEGG	hsa04660	T cell receptor signaling pathway	6/652	104/8135	0.8503	1	1	PPP3R1/IKBKB/PPP3CA/PDCD1/PIK3R1/MAPK12	6
KEGG	hsa04727	GABAergic synapse	5/652	89/8135	0.8514	1	1	GLS/ADCY3/GLUL/ABAT/GABRR2	5
KEGG	hsa05132	Salmonella infection	16/652	249/8135	0.8559	1	1	ROCK2/NOD1/IKBKB/DCTN6/IL6/KLC4/VPS18/DCTN5/HSP90AA1/RAB5B/ACTR3B/DYNLT1/DYNC2LI1/RIPK3/BAK1/MAPK12	16
KEGG	hsa00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	1/652	24/8135	0.8657	1	1	XYLT1	1
KEGG	hsa00860	Porphyrin metabolism	2/652	43/8135	0.87	1	1	ALAS2/FECH	2
KEGG	hsa04730	Long-term depression	3/652	60/8135	0.8701	1	1	ITPR2/PLA2G4C/RYR1	3
KEGG	hsa04978	Mineral absorption	3/652	60/8135	0.8701	1	1	SLC5A1/ATP1A1/SLC8A3	3
KEGG	hsa05014	Amyotrophic lateral sclerosis	24/652	364/8135	0.8705	1	1	BCL2L1/NDUFA12/SETX/NDUFB2/NUP214/UBQLN4/PPP3R1/PSMD12/NUP205/ATXN2/MAP1LC3A/PIK3R4/NEFH/DCTN6/KLC4/DNAH17/DAXX/DNAH10/DCTN5/MTOR/PPP3CA/NUP88/NUP50/MAPK12	24
KEGG	hsa05206	MicroRNAs in cancer	20/652	310/8135	0.8751	1	1	MMP9/SPRY2/HDAC2/APC/RPS6KA5/GLS/IKBKB/TNXB/CDC25C/ITGB3/E2F2/FGFR3/MTOR/ERBB2/MIRLET7D/EFNA4/DNMT3A/BAK1/PIK3R1/E2F1	20
KEGG	hsa03008	Ribosome biogenesis in eukaryotes	6/652	109/8135	0.8794	1	1	HEATR1/RCL1/UTP14A/UTP18/FBLL1/WDR43	6
KEGG	hsa00980	Metabolism of xenobiotics by cytochrome P450	4/652	78/8135	0.8815	1	1	GSTM4/CYP1A1/CYP2D6/CYP2C9	4
KEGG	hsa04932	Non-alcoholic fatty liver disease	9/652	155/8135	0.8834	1	1	NDUFA12/NDUFB2/IKBKB/PPARG/IL6/ADIPOR1/SOCS3/PIK3R1/MAPK12	9
KEGG	hsa04950	Maturity onset diabetes of the young	1/652	26/8135	0.8865	1	1	GCK	1
KEGG	hsa00310	Lysine degradation	3/652	63/8135	0.8905	1	1	SETDB2/DHTKD1/EHHADH	3
KEGG	hsa00062	Fatty acid elongation	1/652	27/8135	0.8956	1	1	ELOVL2	1
KEGG	hsa04929	GnRH secretion	3/652	64/8135	0.8967	1	1	ITPR2/CACNA1H/PIK3R1	3
KEGG	hsa03015	mRNA surveillance pathway	5/652	97/8135	0.8979	1	1	UPF3B/ACIN1/PABPC1L/SMG1/SAP18	5
KEGG	hsa04926	Relaxin signaling pathway	7/652	129/8135	0.9014	1	1	MMP9/RLN3/RXFP3/ADCY3/COL4A6/PIK3R1/MAPK12	7
KEGG	hsa04933	AGE-RAGE signaling pathway in diabetic complications	5/652	100/8135	0.9118	1	1	IL6/COL4A6/STAT5A/PIK3R1/MAPK12	5
KEGG	hsa05030	Cocaine addiction	2/652	49/8135	0.9128	1	1	SLC18A1/DRD2	2
KEGG	hsa00010	Glycolysis / Gluconeogenesis	3/652	67/8135	0.9133	1	1	LDHC/GCK/PFKM	3
KEGG	hsa00030	Pentose phosphate pathway	1/652	30/8135	0.9188	1	1	PFKM	1
KEGG	hsa00053	Ascorbate and aldarate metabolism	1/652	30/8135	0.9188	1	1	UGDH	1
KEGG	hsa05204	Chemical carcinogenesis - DNA adducts	3/652	69/8135	0.923	1	1	GSTM4/CYP1A1/CYP2C9	3
KEGG	hsa04064	NF-kappa B signaling pathway	5/652	104/8135	0.9278	1	1	BCL2L1/IKBKB/DDX58/CXCL1/CARD10	5
KEGG	hsa04620	Toll-like receptor signaling pathway	5/652	104/8135	0.9278	1	1	IKBKB/IL6/PIK3R1/MAPK12/IFNA5	5
KEGG	hsa04520	Adherens junction	3/652	71/8135	0.9317	1	1	ACTN1/ERBB2/PTPN1	3
KEGG	hsa04961	Endocrine and other factor-regulated calcium reabsorption	2/652	53/8135	0.9335	1	1	ATP1A1/SLC8A3	2
KEGG	hsa04928	Parathyroid hormone synthesis, secretion and action	5/652	106/8135	0.9347	1	1	ITPR2/SLC9A3R1/RXRB/ADCY3/BGLAP	5
KEGG	hsa00982	Drug metabolism - cytochrome P450	3/652	72/8135	0.9357	1	1	GSTM4/CYP2D6/CYP2C9	3
KEGG	hsa04340	Hedgehog signaling pathway	2/652	56/8135	0.9459	1	1	SPOP/PTCH2	2
KEGG	hsa05010	Alzheimer disease	23/652	384/8135	0.9493	1	1	ITPR2/NDUFA12/SNCA/NDUFB2/APC/WNT1/PPP3R1/MME/IKBKB/PSMD12/SLC39A5/PIK3R4/WNT16/SLC39A2/IL6/CALM3/PPID/KLC4/WNT2/MTOR/PPP3CA/PIK3R1/DKK4	23
KEGG	hsa00480	Glutathione metabolism	2/652	58/8135	0.9529	1	1	PRDX6/GSTM4	2
KEGG	hsa04070	Phosphatidylinositol signaling system	4/652	97/8135	0.9578	1	1	ITPR2/SACM1L/CALM3/PIK3R1	4
KEGG	hsa04723	Retrograde endocannabinoid signaling	7/652	148/8135	0.9583	1	1	ITPR2/NDUFA12/NDUFB2/NAPEPLD/ADCY3/GABRR2/MAPK12	7
KEGG	hsa05231	Choline metabolism in cancer	4/652	98/8135	0.9602	1	1	SLC22A5/PLA2G4C/MTOR/PIK3R1	4
KEGG	hsa00983	Drug metabolism - other enzymes	3/652	80/8135	0.9607	1	1	MPO/GSTM4/CDA	3
KEGG	hsa00190	Oxidative phosphorylation	6/652	134/8135	0.9632	1	1	NDUFA12/NDUFB2/ATP6V1G3/PPA2/ATP6V1B1/ATP6V1E1	6
KEGG	hsa05033	Nicotine addiction	1/652	40/8135	0.9649	1	1	GABRR2	1
KEGG	hsa04146	Peroxisome	3/652	82/8135	0.9653	1	1	ACSL1/EHHADH/SLC25A17	3
KEGG	hsa04071	Sphingolipid signaling pathway	5/652	119/8135	0.9671	1	1	ROCK2/KNG1/FCER1A/PIK3R1/MAPK12	5
KEGG	hsa05135	Yersinia infection	6/652	137/8135	0.9684	1	1	ROCK2/IKBKB/IL6/ACTR3B/PIK3R1/MAPK12	6
KEGG	hsa05208	Chemical carcinogenesis - reactive oxygen species	11/652	223/8135	0.9741	1	1	NDUFA12/NDUFB2/GSTM4/CYP1A1/IKBKB/SLC26A2/EPHX3/FOXO3/PTPN1/PIK3R1/MAPK12	11
KEGG	hsa00830	Retinol metabolism	2/652	68/8135	0.9768	1	1	CYP1A1/CYP2C9	2
KEGG	hsa05020	Prion disease	14/652	273/8135	0.9771	1	1	ITPR2/NDUFA12/NDUFB2/PPP3R1/PSMD12/C1QB/RYR1/IL6/C1QA/KLC4/HSPA1A/PPP3CA/PIK3R1/MAPK12	14
KEGG	hsa03050	Proteasome	1/652	46/8135	0.9788	1	1	PSMD12	1
KEGG	hsa00620	Pyruvate metabolism	1/652	47/8135	0.9805	1	1	LDHC	1
KEGG	hsa05415	Diabetic cardiomyopathy	9/652	203/8135	0.9853	1	1	MMP9/NDUFA12/NDUFB2/CAMK2G/ACE/MTOR/GYS2/PIK3R1/MAPK12	9
KEGG	hsa05100	Bacterial invasion of epithelial cells	2/652	77/8135	0.9879	1	1	ACTR3B/PIK3R1	2
KEGG	hsa00140	Steroid hormone biosynthesis	1/652	61/8135	0.994	1	1	CYP1A1	1
KEGG	hsa05016	Huntington disease	14/652	306/8135	0.9943	1	1	NDUFA12/HDAC2/NDUFB2/SLC1A3/PSMD12/PPARG/PIK3R4/DCTN6/KLC4/DNAH17/DNAH10/DCTN5/MTOR/TAF4	14
KEGG	hsa05034	Alcoholism	7/652	187/8135	0.9944	1	1	HDAC2/SLC18A1/SLC29A2/CALM3/DRD2/HDAC9/HDAC3	7
KEGG	hsa05032	Morphine addiction	2/652	91/8135	0.9957	1	1	ADCY3/GABRR2	2
KEGG	hsa05211	Renal cell carcinoma	1/652	69/8135	0.9969	1	1	PIK3R1	1
KEGG	hsa00562	Inositol phosphate metabolism	1/652	73/8135	0.9978	1	1	SACM1L	1
KEGG	hsa04740	Olfactory transduction	9/652	440/8135	1	1	1	OR2W3/OR7D2/ADCY3/CAMK2G/CALM3/GNAL/SLC8A3/OR2L2/OR2F1	9