ONTOLOGY	ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	qvalue	geneID	Count
KEGG	hsa05202	Transcriptional misregulation in cancer	39/772	193/8135	3.668e-06	0.001189	0.001074	MAF/ETV1/PBX1/ERG/ELANE/DEFA4/MPO/CEBPE/GZMB/PDGFA/MYC/POLK/TRAF1/ETV7/BCL2L1/CCNA2/BIRC3/MMP9/KLF3/PER2/IGFBP3/JUP/DEFA6/CCNT2/IGF1R/DDB2/JMJD1C/CCNA1/PAX7/REL/CEBPA/PPARG/PBX3/HHEX/TSPAN7/IL1R2/SLC45A3/CDKN1A/MLF1	39
KEGG	hsa04640	Hematopoietic cell lineage	23/772	99/8135	3.817e-05	0.006184	0.005585	ITGA2B/GP1BA/IL2RA/ITGB3/GP9/CD24/CD59/CSF1/IL7R/HLA-DPB1/GYPA/HLA-DMB/CR1L/HLA-DMA/IL1R1/MME/CD1C/ITGA4/IL11RA/EPO/CD1D/IL1R2/CD44	23
KEGG	hsa05215	Prostate cancer	20/772	97/8135	0.0006498	0.07018	0.06339	EGF/ERG/CREB1/PDGFA/HSP90AA1/ARAF/E2F1/MMP9/NRAS/EP300/FGFR2/IGF1R/CCNE1/TCF7L1/PDPK1/NFKBIA/NKX3-1/HSP90B1/IL1R2/CDKN1A	20
KEGG	hsa05219	Bladder cancer	11/772	41/8135	0.001156	0.0936	0.08454	EGF/CDKN2A/MYC/ARAF/E2F1/DAPK2/MMP9/NRAS/RASSF1/MMP1/CDKN1A	11
KEGG	hsa05166	Human T-cell leukemia virus 1 infection	35/772	222/8135	0.001769	0.09871	0.08915	IL2RA/MAD2L1/CREB1/BUB1B/CDKN2A/HLA-B/TGFB2/ADCY6/IL2/MYC/SLC25A5/POLB/ADCY3/E2F1/BCL2L1/CCNA2/HLA-DPB1/NRAS/PTTG1/HLA-DMB/HLA-DMA/IL1R1/JAK3/EP300/CCNE1/CCNA1/NRP1/NFKBIA/CRTC3/FOS/PPP3R1/CALR/IL1R2/CHEK1/CDKN1A	35
KEGG	hsa04360	Axon guidance	30/772	182/8135	0.001828	0.09871	0.08915	MYL9/ABLIM3/L1CAM/SEMA3G/ROBO1/PARD6G/ROBO3/PARD3/SSH1/NRAS/DPYSL5/SLIT1/LIMK2/NTNG1/EPHA1/BMPR2/NTNG2/SEMA6D/PDPK1/NRP1/EPHA2/SLIT3/ROCK2/PPP3R1/SEMA5A/SEMA3D/NTN1/RAC1/SEMA3B/EPHB1	30
KEGG	hsa05210	Colorectal cancer	17/772	86/8135	0.002596	0.1107	0.1	EGF/TGFB2/MYC/POLK/ARAF/NRAS/PMAIP1/DDB2/TCF7L1/FOS/APPL1/MSH6/APC/AREG/BIRC5/RAC1/CDKN1A	17
KEGG	hsa04657	IL-17 signaling pathway	18/772	94/8135	0.002842	0.1107	0.1	TRADD/LCN2/CXCL5/FADD/MAPK11/HSP90AA1/CXCL1/FOSB/MMP9/MAPK13/S100A8/MMP1/ELAVL1/JUND/NFKBIA/FOS/TRAF4/HSP90B1	18
KEGG	hsa04115	p53 signaling pathway	15/772	73/8135	0.003076	0.1107	0.1	CDKN2A/SESN3/FAS/CDK1/BCL2L1/IGFBP3/PPM1D/RRM2/PMAIP1/DDB2/CCNE1/TP73/TNFRSF10B/CHEK1/CDKN1A	15
KEGG	hsa04151	PI3K-Akt signaling pathway	49/772	354/8135	0.004174	0.1247	0.1126	ITGA2B/ITGB5/IL2RA/VEGFC/ITGB3/EGF/GNG11/CREB1/OSM/IL2/PDGFA/CSF1/LPAR5/MYC/COL6A1/HSP90AA1/PPP2R3A/YWHAH/IL7R/BCL2L1/VWF/NRAS/LPAR3/NTF3/DDIT4/JAK3/FGFR2/IGF1R/CCNE1/ITGA9/THBS4/LPAR6/PDPK1/ITGA4/GNG8/EPO/EPHA2/SGK3/HSP90B1/SYK/AREG/PPP2CA/RAC1/IFNA17/LAMC2/MYB/CDKN1A/PPP2R5C/ERBB3	49
KEGG	hsa04380	Osteoclast differentiation	22/772	128/8135	0.004233	0.1247	0.1126	ITGB3/FHL2/SOCS3/CREB1/LILRA4/TGFB2/SOCS1/MAPK11/CSF1/FOSB/FCGR3B/IL1R1/MAPK13/JUND/NFKBIA/PPARG/BLNK/FOS/PPP3R1/NCF4/SYK/RAC1	22
KEGG	hsa05140	Leishmaniasis	15/772	77/8135	0.005225	0.1411	0.1274	TGFB2/MAPK11/MARCKSL1/HLA-DPB1/HLA-DMB/FCGR3B/CR1L/C3/HLA-DMA/MAPK13/IL12A/ITGA4/NFKBIA/FOS/NCF4	15
KEGG	hsa04940	Type I diabetes mellitus	10/772	43/8135	0.005914	0.1474	0.1331	HLA-B/FAS/IL2/ICA1/GZMB/HLA-DPB1/HLA-DMB/HLA-DMA/IL12A/GAD2	10
KEGG	hsa05146	Amoebiasis	18/772	102/8135	0.006964	0.1612	0.1456	CTSG/ARG1/TGFB2/PLCB1/SERPINB10/CXCL1/ARG2/MUC2/C8G/SERPINB6/IL1R1/IL12A/CD1C/GNAL/CD1D/ACTN1/IL1R2/LAMC2	18
KEGG	hsa01524	Platinum drug resistance	14/772	73/8135	0.007892	0.1705	0.154	CDKN2A/FAS/FADD/POLH/BCL2L1/BIRC3/PMAIP1/GSTT1/PDPK1/TOP2A/REV3L/MSH6/BIRC5/CDKN1A	14
KEGG	hsa05221	Acute myeloid leukemia	13/772	67/8135	0.00931	0.1885	0.1703	MPO/CEBPE/PIM1/MYC/ARAF/CCNA2/PIM2/NRAS/PER2/JUP/TCF7L1/CCNA1/CEBPA	13
KEGG	hsa04658	Th1 and Th2 cell differentiation	16/772	92/8135	0.01215	0.2229	0.2013	MAF/IL2RA/IL2/MAPK11/NOTCH2/HLA-DPB1/NFKBIE/HLA-DMB/HLA-DMA/JAK3/MAPK13/IL12A/NFKBIA/GATA3/FOS/PPP3R1	16
KEGG	hsa04061	Viral protein interaction with cytokine and cytokine receptor	17/772	100/8135	0.01238	0.2229	0.2013	CXCL5/PF4/IL2RA/PPBP/PF4V1/CCR6/IL2/CSF1/CCR4/CXCL1/CXCR1/TNFRSF10C/TNFRSF10B/CXCL13/IL22RA1/CCL22/CCR3	17
KEGG	hsa05169	Epstein-Barr virus infection	29/772	202/8135	0.01526	0.2454	0.2217	TRADD/HLA-B/FAS/FADD/MAPK11/MYC/POLK/E2F1/CCNA2/HLA-DPB1/PSMD14/PSMD12/NFKBIE/HLA-DMB/HLA-DMA/JAK3/MAPK13/DDB2/CCNE1/CCNA1/NFKBIA/BLNK/HES1/SYK/CALR/RAC1/CD44/IFNA17/CDKN1A	29
KEGG	hsa04392	Hippo signaling pathway - multiple species	7/772	29/8135	0.01643	0.2454	0.2217	WWC1/DCHS1/RASSF1/LATS2/FRMD6/RASSF4/TEAD3	7
KEGG	hsa05223	Non-small cell lung cancer	13/772	72/8135	0.01678	0.2454	0.2217	EGF/CDKN2A/KIF5C/POLK/ARAF/E2F1/NRAS/RASSF1/JAK3/RET/DDB2/PDPK1/CDKN1A	13
KEGG	hsa04668	TNF signaling pathway	18/772	112/8135	0.01782	0.2454	0.2217	TRADD/CXCL5/VEGFC/BAG4/SOCS3/CREB1/FAS/FADD/MAPK11/CSF1/TRAF1/CXCL1/BIRC3/MMP9/MAPK13/IRF1/NFKBIA/FOS	18
KEGG	hsa00910	Nitrogen metabolism	5/772	17/8135	0.01787	0.2454	0.2217	CA1/CA4/CA2/CA5B/GLUD2	5
KEGG	hsa04630	JAK-STAT signaling pathway	24/772	162/8135	0.01818	0.2454	0.2217	IL2RA/EGF/SOCS3/SOCS1/OSM/IL2/PIM1/PDGFA/MYC/SOCS6/IL7R/IL23R/CISH/BCL2L1/SOCS7/SOCS2/JAK3/EP300/IL12A/IL11RA/EPO/IL22RA1/IFNA17/CDKN1A	24
KEGG	hsa05216	Thyroid cancer	8/772	37/8135	0.02045	0.265	0.2394	MYC/POLK/NRAS/RET/DDB2/TCF7L1/PPARG/CDKN1A	8
KEGG	hsa04218	Cellular senescence	23/772	156/8135	0.02156	0.2685	0.2425	CDKN2A/HLA-B/TGFB2/CDK1/MAPK11/MYC/SLC25A5/RAD9B/E2F1/CCNA2/NRAS/IGFBP3/CAPN2/LIN52/MAPK13/CCNE1/CCNA1/HUS1/PPP3R1/CALM2/PPID/CHEK1/CDKN1A	23
KEGG	hsa05330	Allograft rejection	8/772	38/8135	0.02382	0.2685	0.2425	HLA-B/FAS/IL2/GZMB/HLA-DPB1/HLA-DMB/HLA-DMA/IL12A	8
KEGG	hsa04514	Cell adhesion molecules	22/772	149/8135	0.02387	0.2685	0.2425	SELP/NRCAM/CLDN5/ESAM/L1CAM/HLA-B/PDCD1/HLA-DPB1/NEGR1/HLA-DMB/NTNG1/TIGIT/CNTN2/HLA-DMA/NRXN2/NTNG2/ITGA9/CLDN23/CD274/ITGA4/CTLA4/LRRC4B	22
KEGG	hsa04659	Th17 cell differentiation	17/772	108/8135	0.02519	0.2685	0.2425	IL2RA/IL2/MAPK11/HSP90AA1/IL23R/RORC/HLA-DPB1/NFKBIE/HLA-DMB/HLA-DMA/IL1R1/JAK3/MAPK13/NFKBIA/GATA3/FOS/PPP3R1	17
KEGG	hsa05320	Autoimmune thyroid disease	10/772	53/8135	0.02546	0.2685	0.2425	HLA-B/FAS/IL2/GZMB/HLA-DPB1/TPO/HLA-DMB/HLA-DMA/CTLA4/IFNA17	10
KEGG	hsa05167	Kaposi sarcoma-associated herpesvirus infection	27/772	194/8135	0.027	0.2685	0.2425	TRADD/GNG11/CREB1/HLA-B/FAS/FADD/MAPK11/MYC/CCR4/E2F1/CXCL1/NRAS/C3/EP300/MAPK13/TCF7L1/NFKBIA/GNG8/FOS/PPP3R1/CALM2/SYK/RPS27A/CCR3/RAC1/IFNA17/CDKN1A	27
KEGG	hsa04110	Cell cycle	19/772	126/8135	0.02811	0.2685	0.2425	MAD2L1/BUB1B/CDKN2A/TGFB2/CDK1/MYC/YWHAH/MCM2/E2F1/CCNA2/PTTG1/TTK/EP300/CCNE1/CCNA1/CDC45/CDC25C/CHEK1/CDKN1A	19
KEGG	hsa00531	Glycosaminoglycan degradation	5/772	19/8135	0.02866	0.2685	0.2425	HYAL3/IDS/SGSH/HEXA/HGSNAT	5
KEGG	hsa05203	Viral carcinogenesis	28/772	204/8135	0.02899	0.2685	0.2425	TRADD/CREB1/CDKN2A/HLA-B/CDK1/HPN/CCR4/POLB/YWHAH/TRAF1/CCNA2/NRAS/C3/GTF2E1/JAK3/EP300/PMAIP1/DDB1/CCNE1/CCNA1/NFKBIA/REL/ACTN1/SYK/CCR3/RAC1/CHEK1/CDKN1A	28
KEGG	hsa05142	Chagas disease	16/772	102/8135	0.03015	0.2685	0.2425	TGFB2/C1QA/PLCB1/FAS/FADD/IL2/MAPK11/C3/MAPK13/IL12A/C1QB/GNAL/NFKBIA/FOS/CALR/PPP2CA	16
KEGG	hsa04060	Cytokine-cytokine receptor interaction	38/772	295/8135	0.03108	0.2685	0.2425	CXCL5/PF4/IL2RA/PPBP/PF4V1/ACVR2A/TGFB2/OSM/FAS/CCR6/TNFSF4/IL2/ACVR1/CSF1/TNFRSF21/CCR4/IL7R/IL23R/IL32/CXCL1/INHBA/RELT/CXCR1/TNFRSF18/EDA/IL1R1/BMPR2/IL12A/TNFRSF10C/IL11RA/EPO/TNFRSF10B/CXCL13/IL22RA1/IL1R2/CCL22/CCR3/IFNA17	38
KEGG	hsa04210	Apoptosis	20/772	136/8135	0.03142	0.2685	0.2425	TRADD/TUBA1A/FAS/FADD/GZMB/TRAF1/BCL2L1/BIRC3/SPTA1/PTPN13/NRAS/CAPN2/PMAIP1/PDPK1/NFKBIA/TNFRSF10B/FOS/CASP2/CTSW/BIRC5	20
KEGG	hsa05161	Hepatitis B	23/772	162/8135	0.03199	0.2685	0.2425	CREB1/TGFB2/FAS/FADD/MAPK11/MYC/ARAF/E2F1/CCNA2/MMP9/NRAS/JAK3/EP300/MAPK13/DDB2/DDB1/CCNE1/CCNA1/NFKBIA/FOS/BIRC5/IFNA17/CDKN1A	23
KEGG	hsa03410	Base excision repair	7/772	33/8135	0.03232	0.2685	0.2425	NEIL3/POLB/POLL/NEIL2/TDG/UNG/POLE2	7
KEGG	hsa04068	FoxO signaling pathway	19/772	131/8135	0.03996	0.3175	0.2867	EGF/TGFB2/MAPK11/ARAF/IL7R/S1PR4/GABARAPL2/NRAS/AGAP2/HOMER2/EP300/MAPK13/IGF1R/PRKAG2/PDPK1/FBXO25/PLK4/SGK3/CDKN1A	19
KEGG	hsa04015	Rap1 signaling pathway	28/772	210/8135	0.04018	0.3175	0.2867	ITGA2B/VEGFC/ITGB3/EGF/PLCB1/ADCY6/PARD6G/PDGFA/MAPK11/CSF1/LPAR5/PARD3/VAV3/ID1/ADCY3/CTNND1/NRAS/LPAR3/FGFR2/RAP1GAP/MAPK13/IGF1R/TIAM1/EPHA2/PRKCI/CALM2/DRD2/RAC1	28
KEGG	hsa05144	Malaria	9/772	50/8135	0.04337	0.3218	0.2906	HBB/SELP/TGFB2/GYPB/GYPC/GYPA/CR1L/IL12A/THBS4	9
KEGG	hsa04611	Platelet activation	18/772	124/8135	0.0444	0.3218	0.2906	ITGA2B/GP1BA/ITGB3/GP9/GP6/PLCB1/ADCY6/MAPK11/FGA/ADCY3/PTGS1/VWF/P2RY12/MAPK13/TBXA2R/PRKCI/ROCK2/SYK	18
KEGG	hsa05213	Endometrial cancer	10/772	58/8135	0.04451	0.3218	0.2906	EGF/MYC/POLK/ARAF/NRAS/DDB2/TCF7L1/PDPK1/APC/CDKN1A	10
KEGG	hsa05165	Human papillomavirus infection	41/772	331/8135	0.04469	0.3218	0.2906	TRADD/ITGA2B/ITGB5/ITGB3/EGF/CREB1/HLA-B/FAS/FADD/PARD6G/PARD3/COL6A1/PPP2R3A/ATP6V0A2/NOTCH2/E2F1/CCNA2/MPP5/VWF/NRAS/HES6/EP300/CCNE1/ITGA9/THBS4/TCF7L1/CCNA1/HEY2/ATP6V1E1/IRF1/ITGA4/CSNK1A1/PRKCI/PTGER4/APC/HES1/PPP2CA/IFNA17/LAMC2/CDKN1A/PPP2R5C	41
KEGG	hsa05205	Proteoglycans in cancer	27/772	205/8135	0.04928	0.3471	0.3135	CTTN/ITGB5/ITGB3/CAV2/TGFB2/FAS/ANK1/MIR21/MAPK11/TWIST1/MYC/VAV3/ARAF/MMP9/NRAS/GAB1/MAPK13/IGF1R/ANK3/TIAM1/PDPK1/ROCK2/IHH/RAC1/CD44/CDKN1A/ERBB3	27
KEGG	hsa05417	Lipid and atherosclerosis	28/772	215/8135	0.05174	0.3499	0.316	SELP/PLCB1/VLDLR/FAS/MAPK11/VAV3/HSP90AA1/BCL2L1/CXCL1/MMP9/NRAS/MAPK13/IL12A/MMP1/PDPK1/NFKBIA/TNFRSF10B/PPARG/FOS/ROCK2/PPP3R1/HSP90B1/CALM2/NCF4/POU2F2/RAC1/IFNA17/HSPA1A	28
KEGG	hsa05130	Pathogenic Escherichia coli infection	26/772	197/8135	0.05183	0.3499	0.316	TRADD/CTTN/CLDN5/TUBB1/TUBA1A/FAS/FADD/MYO1E/WASF3/MAPK11/LPAR5/MYH11/TMED10/IL1R1/MAPK13/CLDN23/NFKBIA/BAIAP2L1/TNFRSF10B/FOS/CASP4/ROCK2/WASF1/TUBB6/RAC1/WIPF1	26
KEGG	hsa05212	Pancreatic cancer	12/772	76/8135	0.05325	0.3521	0.318	EGF/CDKN2A/TGFB2/POLK/ARAF/E2F1/BCL2L1/RAD51/DDB2/RALBP1/RAC1/CDKN1A	12
KEGG	hsa04914	Progesterone-mediated oocyte maturation	15/772	102/8135	0.05703	0.3695	0.3338	MAD2L1/ADCY6/CDK1/MAPK11/HSP90AA1/ARAF/ADCY3/CCNA2/MAPK13/KIF22/IGF1R/CCNA1/CDC25C/CPEB3/MOS	15
KEGG	hsa00590	Arachidonic acid metabolism	10/772	61/8135	0.05967	0.3791	0.3424	ALOX12/CYP4F3/CYP4F2/PTGDS/CBR3/GGT1/PTGS1/CYP2U1/AKR1C3/LTC4S	10
KEGG	hsa04062	Chemokine signaling pathway	25/772	192/8135	0.06346	0.3863	0.3489	CXCL5/PF4/PPBP/PF4V1/GNG11/PLCB1/CCR6/ADCY6/PARD3/VAV3/CCR4/ADCY3/CXCL1/NRAS/CXCR1/JAK3/GRK7/TIAM1/NFKBIA/GNG8/CXCL13/ROCK2/CCL22/CCR3/RAC1	25
KEGG	hsa04917	Prolactin signaling pathway	11/772	70/8135	0.0643	0.3863	0.3489	SOCS3/SOCS1/MAPK11/SOCS6/CISH/SOCS7/NRAS/SOCS2/MAPK13/IRF1/FOS	11
KEGG	hsa03460	Fanconi anemia pathway	9/772	54/8135	0.06585	0.3863	0.3489	RAD51C/POLH/POLK/PALB2/UBE2T/FANCI/RAD51/REV3L/HES1	9
KEGG	hsa05418	Fluid shear stress and atherosclerosis	19/772	139/8135	0.06591	0.3863	0.3489	ITGA2B/ITGB3/CAV2/ACVR2A/ACVR1/PDGFA/MAPK11/HSP90AA1/MMP9/IL1R1/BMPR2/MAPK13/GSTT1/FOS/HSP90B1/CALM2/KEAP1/IL1R2/RAC1	19
KEGG	hsa04390	Hippo signaling pathway	21/772	157/8135	0.06676	0.3863	0.3489	WWC1/TGFB2/PARD6G/PARD3/MYC/YWHAH/ID1/BIRC3/MPP5/RASSF1/LATS2/BMPR2/TCF7L1/FRMD6/TP73/PRKCI/APC/AREG/PPP2CA/BIRC5/TEAD3	21
KEGG	hsa05150	Staphylococcus aureus infection	14/772	96/8135	0.06821	0.3865	0.3491	SELP/CAMP/DEFA4/C1QA/HLA-DPB1/HLA-DMB/FCGR3B/C3/HLA-DMA/DEFA6/KRT25/C1QB/KRT12/KRT10	14
KEGG	hsa04114	Oocyte meiosis	18/772	131/8135	0.06918	0.3865	0.3491	MAD2L1/ADCY6/CDK1/MAPK11/YWHAH/ADCY3/PTTG1/MAPK13/IGF1R/CCNE1/STAG3/PPP3R1/CALM2/PPP2CA/CDC25C/CPEB3/MOS/PPP2R5C	18
KEGG	hsa04512	ECM-receptor interaction	13/772	88/8135	0.07085	0.3891	0.3514	ITGA2B/ITGB5/GP1BA/ITGB3/GP9/GP6/COL6A1/VWF/ITGA9/THBS4/ITGA4/CD44/LAMC2	13
KEGG	hsa04142	Lysosome	18/772	132/8135	0.07336	0.3897	0.3519	CTSG/ATP6V0A2/AP3M2/HYAL3/IDS/SGSH/CLTA/HEXA/AP1S3/CTSE/NEU1/AP1M2/HGSNAT/CD68/LIPA/SCARB2/CTSW/LAPTM4B	18
KEGG	hsa04728	Dopaminergic synapse	18/772	132/8135	0.07336	0.3897	0.3519	GNG11/CREB1/PLCB1/MAPK11/KIF5C/PPP2R3A/MAPK13/GNAL/GNG8/SLC18A2/FOS/CALM2/KCNJ3/PPP2CA/DRD2/PPP1R1B/DRD3/PPP2R5C	18
KEGG	hsa01522	Endocrine resistance	14/772	98/8135	0.07823	0.4088	0.3692	CDKN2A/ADCY6/MAPK11/ARAF/NOTCH2/ADCY3/E2F1/MMP9/NRAS/MAPK13/IGF1R/NCOA3/FOS/CDKN1A	14
KEGG	hsa05163	Human cytomegalovirus infection	28/772	225/8135	0.08176	0.4153	0.3751	TRADD/ITGB3/GNG11/CREB1/CDKN2A/HLA-B/PLCB1/FAS/ADCY6/FADD/MAPK11/MYC/ADCY3/E2F1/NRAS/IL1R1/MAPK13/NFKBIA/GNG8/PTGER4/ROCK2/PPP3R1/CALM2/CALR/CCR3/RAC1/IFNA17/CDKN1A	28
KEGG	hsa04145	Phagosome	20/772	152/8135	0.0825	0.4153	0.3751	ITGB5/TUBB1/ITGB3/TUBA1A/HLA-B/MPO/SEC61B/ATP6V0A2/HLA-DPB1/HLA-DMB/FCGR3B/C3/HLA-DMA/THBS4/ATP6V1E1/NCF4/VAMP3/CALR/TUBB6/RAC1	20
KEGG	hsa00061	Fatty acid biosynthesis	4/772	18/8135	0.08422	0.4153	0.3751	OLAH/MCAT/OXSM/ACSL3	4
KEGG	hsa05321	Inflammatory bowel disease	10/772	65/8135	0.0846	0.4153	0.3751	MAF/TGFB2/IL2/IL23R/RORC/HLA-DPB1/HLA-DMB/HLA-DMA/IL12A/GATA3	10
KEGG	hsa05222	Small cell lung cancer	13/772	92/8135	0.09348	0.452	0.4083	ITGA2B/MYC/POLK/TRAF1/E2F1/BCL2L1/BIRC3/DDB2/CCNE1/NFKBIA/TRAF4/LAMC2/CDKN1A	13
KEGG	hsa05214	Glioma	11/772	75/8135	0.09529	0.454	0.4101	EGF/CDKN2A/PDGFA/POLK/ARAF/E2F1/NRAS/IGF1R/DDB2/CALM2/CDKN1A	11
KEGG	hsa05332	Graft-versus-host disease	7/772	42/8135	0.0981	0.4607	0.4161	HLA-B/FAS/IL2/GZMB/HLA-DPB1/HLA-DMB/HLA-DMA	7
KEGG	hsa05133	Pertussis	11/772	76/8135	0.1024	0.4673	0.4221	CXCL5/C1QA/IRF8/MAPK11/C3/MAPK13/IL12A/C1QB/IRF1/FOS/CALM2	11
KEGG	hsa05220	Chronic myeloid leukemia	11/772	76/8135	0.1024	0.4673	0.4221	CDKN2A/TGFB2/MYC/POLK/ARAF/E2F1/BCL2L1/NRAS/DDB2/NFKBIA/CDKN1A	11
KEGG	hsa04610	Complement and coagulation cascades	12/772	85/8135	0.1047	0.4713	0.4256	CLU/PROS1/CD59/C1QA/PROC/FGA/VWF/CR1L/C3/C8G/C1QB/F13A1	12
KEGG	hsa04350	TGF-beta signaling pathway	13/772	94/8135	0.1063	0.4717	0.4261	LTBP1/GREM2/LEFTY1/ACVR2A/TGFB2/ACVR1/MYC/ID1/INHBA/NOG/BMPR2/EP300/PPP2CA	13
KEGG	hsa04261	Adrenergic signaling in cardiomyocytes	19/772	150/8135	0.1175	0.5078	0.4587	SCN5A/CREB1/SCN1B/PLCB1/ADCY6/MAPK11/SLC8A3/TPM1/PPP2R3A/MYL4/FXYD2/ADCY3/CACNA2D2/TNNC1/CACNA2D3/MAPK13/CALM2/PPP2CA/PPP2R5C	19
KEGG	hsa04721	Synaptic vesicle cycle	11/772	78/8135	0.1175	0.5078	0.4587	STX2/STXBP1/ATP6V0A2/DNM3/SLC6A4/CLTA/SLC32A1/SLC6A7/ATP6V1E1/SLC18A2/SLC6A13	11
KEGG	hsa05414	Dilated cardiomyopathy	13/772	96/8135	0.1201	0.512	0.4624	ITGA2B/ITGB5/ITGB3/TGFB2/ADCY6/SLC8A3/TPM1/ADCY3/CACNA2D2/TNNC1/CACNA2D3/ITGA9/ITGA4	13
KEGG	hsa05152	Tuberculosis	22/772	180/8135	0.1294	0.5266	0.4756	TRADD/CAMP/CREB1/TGFB2/FADD/MAPK11/ATP6V0A2/HLA-DPB1/HLA-DMB/FCGR3B/CR1L/C3/HLA-DMA/EP300/MAPK13/NFYA/IL12A/CEBPG/PPP3R1/CALM2/SYK/IFNA17	22
KEGG	hsa04550	Signaling pathways regulating pluripotency of stem cells	18/772	143/8135	0.1305	0.5266	0.4756	LEFTY1/ACVR2A/KLF4/ACVR1/MAPK11/MYC/ID1/NRAS/INHBA/BMPR2/JAK3/FGFR2/MAPK13/IGF1R/TBX3/JARID2/APC/PCGF5	18
KEGG	hsa04810	Regulation of actin cytoskeleton	26/772	218/8135	0.1311	0.5266	0.4756	MYL9/ITGA2B/ITGB5/ITGB3/EGF/IQGAP3/PDGFA/LPAR5/MYH11/VAV3/ARAF/CHRM4/SSH1/NRAS/LIMK2/FGFR2/ITGA9/DIAPH3/TIAM1/ITGA4/ROCK2/ACTN1/APC/WASF1/RAC1/MOS	26
KEGG	hsa04141	Protein processing in endoplasmic reticulum	21/772	171/8135	0.1313	0.5266	0.4756	EIF2AK4/HSP90AA1/PPP1R15A/SEC61B/LMAN1L/RAD23A/DNAJA1/SEC62/CAPN2/DNAJC10/UBXN6/HSPH1/YOD1/MBTPS1/DERL1/VCP/NGLY1/HSP90B1/CALR/HSPA1A/DDOST	21
KEGG	hsa04613	Neutrophil extracellular trap formation	23/772	190/8135	0.1327	0.5266	0.4756	SELP/ITGA2B/GP1BA/CAMP/ITGB3/CTSG/ELANE/MPO/AZU1/PLCB1/MAPK11/FGA/SLC25A5/VWF/FCGR3B/CR1L/C3/MAPK13/CASP4/NCF4/SYK/CLCN5/RAC1	23
KEGG	hsa00250	Alanine, aspartate and glutamate metabolism	6/772	37/8135	0.1333	0.5266	0.4756	AGXT2/IL4I1/ADSL/ALDH5A1/GAD2/GLUD2	6
KEGG	hsa05218	Melanoma	10/772	72/8135	0.1414	0.551	0.4977	EGF/CDKN2A/PDGFA/POLK/ARAF/E2F1/NRAS/IGF1R/DDB2/CDKN1A	10
KEGG	hsa05410	Hypertrophic cardiomyopathy	12/772	90/8135	0.1429	0.551	0.4977	ITGA2B/ITGB5/ITGB3/TGFB2/SLC8A3/TPM1/CACNA2D2/TNNC1/CACNA2D3/ITGA9/PRKAG2/ITGA4	12
KEGG	hsa04024	cAMP signaling pathway	26/772	221/8135	0.1464	0.5581	0.5041	MYL9/CREB1/HTR1B/EDN3/ADCY6/OXTR/VAV3/SUCNR1/FXYD2/ADCY3/LIPE/GPHA2/EP300/GHSR/TIAM1/NFKBIA/ABCC4/VIP/FOS/ROCK2/CALM2/DRD2/PPP1R1B/RAC1/CRH/PDE3A	26
KEGG	hsa04926	Relaxin signaling pathway	16/772	129/8135	0.1611	0.607	0.5483	VEGFC/GNG11/CREB1/PLCB1/ADCY6/MAPK11/ADCY3/MMP9/NRAS/INSL3/MAPK13/MMP1/NFKBIA/GNG8/RXFP2/FOS	16
KEGG	hsa00603	Glycosphingolipid biosynthesis - globo and isoglobo series	3/772	15/8135	0.1646	0.6079	0.549	ST8SIA1/HEXA/FUT2	3
KEGG	hsa03430	Mismatch repair	4/772	23/8135	0.1686	0.6079	0.549	MLH3/RFC1/EXO1/MSH6	4
KEGG	hsa04964	Proximal tubule bicarbonate reclamation	4/772	23/8135	0.1686	0.6079	0.549	FXYD2/CA4/CA2/GLUD2	4
KEGG	hsa05323	Rheumatoid arthritis	12/772	93/8135	0.1688	0.6079	0.549	CXCL5/TGFB2/CSF1/ATP6V0A2/CXCL1/HLA-DPB1/HLA-DMB/HLA-DMA/MMP1/ATP6V1E1/CTLA4/FOS	12
KEGG	hsa05145	Toxoplasmosis	14/772	112/8135	0.1737	0.6184	0.5585	TGFB2/SOCS1/MAPK11/BCL2L1/HLA-DPB1/BIRC3/HLA-DMB/HLA-DMA/MAPK13/IL12A/PDPK1/NFKBIA/HSPA1A/LAMC2	14
KEGG	hsa04530	Tight junction	20/772	169/8135	0.1775	0.6226	0.5623	MYL9/CTTN/CLDN5/TUBA1A/PARD6G/MYH11/PARD3/RAB13/MPP5/TJP3/PRKAG2/CD1C/CLDN23/TIAM1/PRKCI/CD1D/ROCK2/ACTN1/PPP2CA/RAC1	20
KEGG	hsa00520	Amino sugar and nucleotide sugar metabolism	7/772	49/8135	0.1787	0.6226	0.5623	UGP2/CHIT1/HEXA/GPI/NANS/CYB5RL/CMAS	7
KEGG	hsa04215	Apoptosis - multiple species	5/772	32/8135	0.1821	0.6276	0.5668	FADD/BCL2L1/BIRC3/PMAIP1/BIRC5	5
KEGG	hsa04660	T cell receptor signaling pathway	13/772	104/8135	0.1849	0.6305	0.5694	IL2/MAPK11/VAV3/GRAP2/PDCD1/NRAS/NFKBIE/MAPK13/PDPK1/NFKBIA/CTLA4/FOS/PPP3R1	13
KEGG	hsa04936	Alcoholic liver disease	17/772	142/8135	0.1884	0.6331	0.5718	TRADD/C1QA/FAS/FADD/MAPK11/CPT1C/CXCL1/TRA2B/C3/MAPK13/IL12A/C1QB/TCF7L1/PRKAG2/NFKBIA/LPIN2/IFNA17	17
KEGG	hsa04670	Leukocyte transendothelial migration	14/772	114/8135	0.1908	0.6331	0.5718	MYL9/CLDN5/ESAM/MAPK11/VAV3/CTNND1/MMP9/MAPK13/CLDN23/ITGA4/ROCK2/ACTN1/NCF4/RAC1	14
KEGG	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	10/772	77/8135	0.1915	0.6331	0.5718	ITGA2B/ITGB5/ITGB3/SLC8A3/CACNA2D2/JUP/CACNA2D3/ITGA9/TCF7L1/ITGA4	10
KEGG	hsa04612	Antigen processing and presentation	10/772	78/8135	0.2024	0.6623	0.5981	CREB1/HLA-B/HSP90AA1/HLA-DPB1/HLA-DMB/HLA-DMA/NFYA/CALR/KLRC4/HSPA1A	10
KEGG	hsa05170	Human immunodeficiency virus 1 infection	24/772	212/8135	0.2078	0.6732	0.608	TRADD/GNG11/HLA-B/FAS/CDK1/FADD/MAPK11/BCL2L1/NRAS/AP1S3/LIMK2/MAPK13/DDB1/AP1M2/NFKBIA/GNG8/FOS/PPP3R1/CALM2/CALR/CDC25C/RAC1/CHEK1/IFNA17	24
KEGG	hsa04540	Gap junction	11/772	88/8135	0.2103	0.6746	0.6093	TUBB1/EGF/TUBA1A/PLCB1/ADCY6/CDK1/PDGFA/ADCY3/NRAS/DRD2/TUBB6	11
KEGG	hsa01521	EGFR tyrosine kinase inhibitor resistance	10/772	79/8135	0.2135	0.677	0.6115	EGF/PDGFA/ARAF/BCL2L1/NRAS/GAB1/FGFR2/IGF1R/NF1/ERBB3	10
KEGG	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	9/772	70/8135	0.2163	0.677	0.6115	MAPK11/ATP6V0A2/CXCL1/CXCR1/MAPK13/ATP6V1E1/NFKBIA/PTPRZ1/RAC1	9
KEGG	hsa04727	GABAergic synapse	11/772	89/8135	0.2209	0.677	0.6115	GNG11/ADCY6/TRAK2/SLC38A5/ADCY3/GABARAPL2/SLC32A1/GABRP/GAD2/GNG8/SLC6A13	11
KEGG	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	11/772	89/8135	0.2209	0.677	0.6115	EGF/BATF/MAPK11/PDCD1/NRAS/NFKBIE/MAPK13/CD274/NFKBIA/FOS/PPP3R1	11
KEGG	hsa04080	Neuroactive ligand-receptor interaction	38/772	353/8135	0.2257	0.677	0.6115	CTSG/HTR1B/EDN3/OXTR/PARD3/S1PR4/CHRM4/PMCH/P2RX7/INSL3/SCT/GRM4/LPAR3/C3/P2RX3/GALR3/GPHA2/ADRA2A/NPFFR1/GABRP/TBXA2R/LPAR6/GHSR/CYSLTR2/P2RY2/F2RL1/VIP/GNRHR/RXFP2/PTGER4/ADRA2B/NTS/DRD2/GPR35/TAAR5/P2RX6/DRD3/CRH	38
KEGG	hsa04520	Adherens junction	9/772	71/8135	0.2285	0.677	0.6115	WASF3/PARD3/CTNND1/EP300/IGF1R/TCF7L1/ACTN1/WASF1/RAC1	9
KEGG	hsa05224	Breast cancer	17/772	147/8135	0.229	0.677	0.6115	EGF/MYC/POLK/ARAF/NOTCH2/E2F1/NRAS/IGF1R/DDB2/NCOA3/TCF7L1/HEY2/CSNK1A1/FOS/APC/HES1/CDKN1A	17
KEGG	hsa05160	Hepatitis C	18/772	157/8135	0.2318	0.677	0.6115	TRADD/EIF2AK4/CLDN5/EGF/SOCS3/FAS/FADD/MYC/ARAF/YWHAH/E2F1/NRAS/CLDN23/NFKBIA/PPP2CA/RSAD2/IFNA17/CDKN1A	18
KEGG	hsa04915	Estrogen signaling pathway	16/772	138/8135	0.2346	0.677	0.6115	CREB1/PLCB1/ADCY6/HSP90AA1/ADCY3/MMP9/NRAS/KRT25/NCOA3/KRT12/FOS/HSP90B1/CALM2/KRT10/KCNJ3/HSPA1A	16
KEGG	hsa04962	Vasopressin-regulated water reabsorption	6/772	44/8135	0.2355	0.677	0.6115	CREB1/ADCY6/ADCY3/AQP3/DCTN4/DYNC2LI1	6
KEGG	hsa04935	Growth hormone synthesis, secretion and action	14/772	119/8135	0.2367	0.677	0.6115	SOCS3/CREB1/SOCS1/PLCB1/ADCY6/MAPK11/ADCY3/NRAS/IGFBP3/SOCS2/EP300/MAPK13/GHSR/FOS	14
KEGG	hsa05162	Measles	16/772	139/8135	0.2435	0.677	0.6115	TRADD/EIF2AK4/IL2RA/SLAMF1/FAS/FADD/IL2/BCL2L1/JAK3/CCNE1/IL12A/TP73/NFKBIA/FOS/IFNA17/HSPA1A	16
KEGG	hsa05226	Gastric cancer	17/772	149/8135	0.2462	0.677	0.6115	EGF/TGFB2/MYC/POLK/ARAF/E2F1/NRAS/MUC2/JUP/GAB1/FGFR2/DDB2/CCNE1/TCF7L1/CSNK1A1/APC/CDKN1A	17
KEGG	hsa04152	AMPK signaling pathway	14/772	120/8135	0.2463	0.677	0.6115	CREB1/CPT1C/PPP2R3A/STRADB/CCNA2/LIPE/IGF1R/PRKAG2/CCNA1/ELAVL1/PDPK1/PPARG/PPP2CA/PPP2R5C	14
KEGG	hsa04662	B cell receptor signaling pathway	10/772	82/8135	0.2483	0.677	0.6115	LILRA4/VAV3/NRAS/NFKBIE/NFKBIA/BLNK/FOS/PPP3R1/SYK/RAC1	10
KEGG	hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	4/772	27/8135	0.2506	0.677	0.6115	B3GALT2/ST8SIA1/FUT2/ABO	4
KEGG	hsa04966	Collecting duct acid secretion	4/772	27/8135	0.2506	0.677	0.6115	SLC4A1/ATP6V0A2/CA2/ATP6V1E1	4
KEGG	hsa00500	Starch and sucrose metabolism	5/772	36/8135	0.2528	0.677	0.6115	UGP2/ENPP3/MGAM/GPI/PGM2L1	5
KEGG	hsa00512	Mucin type O-glycan biosynthesis	5/772	36/8135	0.2528	0.677	0.6115	ST6GALNAC1/GALNT14/GALNT6/GALNT9/GCNT3	5
KEGG	hsa00760	Nicotinate and nicotinamide metabolism	5/772	36/8135	0.2528	0.677	0.6115	SIRT2/ENPP3/NUDT12/NT5DC4/NMNAT1	5
KEGG	hsa05132	Salmonella infection	27/772	249/8135	0.2588	0.6872	0.6207	MYL9/TRADD/TUBB1/TUBA1A/FADD/WASF3/MAPK11/KIF5C/MYC/HSP90AA1/AHNAK2/ELMO2/BIRC3/VPS33A/DCTN4/DYNC2LI1/MAPK13/TCF7L1/SNX33/NFKBIA/TNFRSF10B/FOS/CASP4/ROCK2/HSP90B1/TUBB6/RAC1	27
KEGG	hsa04510	Focal adhesion	22/772	201/8135	0.2705	0.7038	0.6356	MYL9/ITGA2B/ITGB5/VEGFC/ITGB3/EGF/CAV2/PDGFA/VAV3/COL6A1/BIRC3/VWF/CAPN2/IGF1R/ITGA9/THBS4/PDPK1/ITGA4/ROCK2/ACTN1/RAC1/LAMC2	22
KEGG	hsa04120	Ubiquitin mediated proteolysis	16/772	142/8135	0.2711	0.7038	0.6356	RHOBTB1/SOCS3/SOCS1/UBE2O/BIRC3/UBE2C/UBE3C/TRIM32/DDB2/DDB1/CBLC/UBE2QL1/KEAP1/RPS27A/UBA1/UBE2E2	16
KEGG	hsa05143	African trypanosomiasis	5/772	37/8135	0.2715	0.7038	0.6356	HBB/PLCB1/FAS/IL12A/F2RL1	5
KEGG	hsa05171	Coronavirus disease - COVID-19	25/772	232/8135	0.2796	0.7112	0.6424	SELP/C1QA/IL2/RPS26/MAPK11/FGA/RPS27/VWF/C3/C8G/RPS28/RPS15/MAPK13/IL12A/C1QB/MMP1/NRP1/NFKBIA/FOS/F13A1/RPS21/SYK/RPS27A/RPL18/IFNA17	25
KEGG	hsa03320	PPAR signaling pathway	9/772	75/8135	0.2796	0.7112	0.6424	SLC27A2/CPT1C/MMP1/SLC27A1/PDPK1/SLC27A5/PPARG/EHHADH/ACSL3	9
KEGG	hsa04625	C-type lectin receptor signaling pathway	12/772	104/8135	0.281	0.7112	0.6424	CLEC1B/IL2/MAPK11/NRAS/MAPK13/IL12A/IRF1/NFKBIA/PPP3R1/CALM2/SYK/CCL22	12
KEGG	hsa03420	Nucleotide excision repair	6/772	47/8135	0.2851	0.7161	0.6468	RAD23A/RFC1/DDB2/DDB1/XPC/POLE2	6
KEGG	hsa00100	Steroid biosynthesis	3/772	20/8135	0.294	0.7229	0.6529	CYP51A1/FDFT1/LIPA	3
KEGG	hsa01212	Fatty acid metabolism	7/772	57/8135	0.2945	0.7229	0.6529	ELOVL7/CPT1C/FADS1/MCAT/OXSM/EHHADH/ACSL3	7
KEGG	hsa05134	Legionellosis	7/772	57/8135	0.2945	0.7229	0.6529	CXCL1/CR1L/C3/IL12A/NFKBIA/VCP/HSPA1A	7
KEGG	hsa04928	Parathyroid hormone synthesis, secretion and action	12/772	106/8135	0.3036	0.7395	0.6679	CREB1/PLCB1/ADCY6/MMP25/ARAF/ADCY3/JUND/GATA3/MEF2D/FOS/BGLAP/CDKN1A	12
KEGG	hsa01523	Antifolate resistance	4/772	30/8135	0.3165	0.7652	0.6911	ALOX12/ATIC/ABCG2/ABCC4	4
KEGG	hsa04750	Inflammatory mediator regulation of TRP channels	11/772	98/8135	0.325	0.7701	0.6956	ALOX12/PLCB1/ADCY6/MAPK11/ADCY3/IL1R1/MAPK13/P2RY2/F2RL1/PTGER4/CALM2	11
KEGG	hsa00230	Purine metabolism	14/772	128/8135	0.3285	0.7701	0.6956	GMPR/GUCY2D/ADCY6/PDE8B/ADCY3/ENPP3/AMPD3/ADSL/RRM2/NT5DC4/ATIC/PAICS/ALLC/PDE3A	14
KEGG	hsa05225	Hepatocellular carcinoma	18/772	168/8135	0.3291	0.7701	0.6956	CDKN2A/TGFB2/MYC/POLK/ARAF/E2F1/BCL2L1/NRAS/GAB1/IGF1R/DDB2/TCF7L1/ARID1A/GSTT1/CSNK1A1/APC/KEAP1/CDKN1A	18
KEGG	hsa04924	Renin secretion	8/772	69/8135	0.3304	0.7701	0.6956	CREB1/PLCB1/EDN3/ADCY6/PTGER4/PPP3R1/CALM2/PDE3A	8
KEGG	hsa05211	Renal cell carcinoma	8/772	69/8135	0.3304	0.7701	0.6956	TGFB2/FLCN/ARAF/NRAS/GAB1/EP300/RAC1/CDKN1A	8
KEGG	hsa03018	RNA degradation	9/772	79/8135	0.3335	0.7719	0.6972	TOB2/PABPC1/CNOT4/MPHOSPH6/DCP1B/CNOT8/ENO2/BTG4/CNOT2	9
KEGG	hsa04710	Circadian rhythm	4/772	31/8135	0.3388	0.7731	0.6982	CREB1/RORC/PER2/PRKAG2	4
KEGG	hsa05310	Asthma	4/772	31/8135	0.3388	0.7731	0.6982	RNASE3/HLA-DPB1/HLA-DMB/HLA-DMA	4
KEGG	hsa04730	Long-term depression	7/772	60/8135	0.3418	0.7744	0.6994	GNAZ/PLCB1/ARAF/NRAS/IGF1R/PPP2CA/CRH	7
KEGG	hsa00220	Arginine biosynthesis	3/772	22/8135	0.3481	0.7787	0.7033	ARG1/ARG2/GLUD2	3
KEGG	hsa03440	Homologous recombination	5/772	41/8135	0.3485	0.7787	0.7033	RAD51C/PALB2/BARD1/RAD51/RAD54L	5
KEGG	hsa03450	Non-homologous end-joining	2/772	13/8135	0.3536	0.7847	0.7087	XRCC6/POLL	2
KEGG	hsa04614	Renin-angiotensin system	3/772	23/8135	0.375	0.8265	0.7465	CTSG/MME/NLN	3
KEGG	hsa04130	SNARE interactions in vesicular transport	4/772	33/8135	0.3836	0.8366	0.7556	STX2/STX8/VAMP3/BET1L	4
KEGG	hsa00860	Porphyrin metabolism	5/772	43/8135	0.3876	0.8366	0.7556	ALAS2/ALAS1/UROD/FECH/ALAD	5
KEGG	hsa04961	Endocrine and other factor-regulated calcium reabsorption	6/772	53/8135	0.3893	0.8366	0.7556	PLCB1/ADCY6/SLC8A3/FXYD2/DNM3/CLTA	6
KEGG	hsa00310	Lysine degradation	7/772	63/8135	0.3899	0.8366	0.7556	PLOD2/AASS/PRDM16/EHHADH/SMYD3/PRDM6/SUV39H1	7
KEGG	hsa04012	ErbB signaling pathway	9/772	85/8135	0.4171	0.8624	0.7789	EGF/NRG4/MYC/ARAF/NRAS/GAB1/AREG/CDKN1A/ERBB3	9
KEGG	hsa04022	cGMP-PKG signaling pathway	17/772	167/8135	0.4178	0.8624	0.7789	MYL9/CREB1/PLCB1/ADCY6/SLC8A3/SLC25A5/FXYD2/ADCY3/GTF2IRD1/NPPB/ADRA2A/MEF2D/ROCK2/PPP3R1/ADRA2B/CALM2/PDE3A	17
KEGG	hsa04918	Thyroid hormone synthesis	8/772	75/8135	0.4196	0.8624	0.7789	CREB1/PLCB1/ADCY6/FXYD2/ADCY3/TPO/TTF1/HSP90B1	8
KEGG	hsa04927	Cortisol synthesis and secretion	7/772	65/8135	0.422	0.8624	0.7789	PBX1/CREB1/PLCB1/ADCY6/PDE8B/ADCY3/CYP21A2	7
KEGG	hsa00604	Glycosphingolipid biosynthesis - ganglio series	2/772	15/8135	0.4235	0.8624	0.7789	ST8SIA1/HEXA	2
KEGG	hsa00730	Thiamine metabolism	2/772	15/8135	0.4235	0.8624	0.7789	ALPL/TPK1	2
KEGG	hsa02010	ABC transporters	5/772	45/8135	0.4265	0.8624	0.7789	ABCA9/ABCA13/ABCG2/ABCC4/ABCA7	5
KEGG	hsa04144	Endocytosis	25/772	251/8135	0.4302	0.8624	0.7789	IL2RA/CAV2/HLA-B/PARD6G/EHD3/PARD3/KIF5C/PSD3/ASAP2/DNM3/CLTA/AGAP2/DNAJC6/CXCR1/FGFR2/EHD2/IGF1R/GRK7/CBLC/PRKCI/CHMP1B/RUFY1/HSPA1A/WIPF1/ACAP2	25
KEGG	hsa04072	Phospholipase D signaling pathway	15/772	148/8135	0.4344	0.8624	0.7789	EGF/PLCB1/ADCY6/PDGFA/LPAR5/ADCY3/DNM3/NRAS/CXCR1/GRM4/LPAR3/GAB1/LPAR6/SYK/DGKA	15
KEGG	hsa04723	Retrograde endocannabinoid signaling	15/772	148/8135	0.4344	0.8624	0.7789	MGLL/GNG11/PLCB1/ADCY6/MAPK11/ADCY3/NDUFA10/NDUFB2/SLC32A1/MAPK13/GABRP/GNG8/FAAH/KCNJ3/NDUFV2	15
KEGG	hsa03015	mRNA surveillance pathway	10/772	97/8135	0.441	0.8624	0.7789	PPP2R3A/PABPC1/CASC3/CSTF1/CSTF2T/PAPOLA/NXF3/CSTF2/PPP2CA/PPP2R5C	10
KEGG	hsa04713	Circadian entrainment	10/772	97/8135	0.441	0.8624	0.7789	GNG11/CREB1/PLCB1/ADCY6/ADCY3/PER2/GNG8/FOS/CALM2/KCNJ3	10
KEGG	hsa04010	MAPK signaling pathway	29/772	294/8135	0.4417	0.8624	0.7789	TRADD/VEGFC/EGF/TGFB2/FAS/PDGFA/MAPK11/CSF1/MYC/DUSP16/ARAF/CACNA2D2/NRAS/CACNA2D3/IL1R1/NTF3/FGFR2/MAPK13/IGF1R/JUND/MKNK2/EPHA2/FOS/PPP3R1/NF1/AREG/RAC1/HSPA1A/ERBB3	29
KEGG	hsa05100	Bacterial invasion of epithelial cells	8/772	77/8135	0.4493	0.8624	0.7789	CTTN/CAV2/DNM3/ELMO2/CLTA/GAB1/WASF1/RAC1	8
KEGG	hsa00350	Tyrosine metabolism	4/772	36/8135	0.4499	0.8624	0.7789	HGD/TPO/PNMT/IL4I1	4
KEGG	hsa00563	Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	3/772	26/8135	0.4539	0.8624	0.7789	PIGH/PGAP1/PIGN	3
KEGG	hsa05231	Choline metabolism in cancer	10/772	98/8135	0.4541	0.8624	0.7789	EGF/PCYT1B/WASF3/PDGFA/NRAS/PDPK1/FOS/WASF1/DGKA/RAC1	10
KEGG	hsa00430	Taurine and hypotaurine metabolism	2/772	16/8135	0.457	0.8624	0.7789	GGT1/GAD2	2
KEGG	hsa04071	Sphingolipid signaling pathway	12/772	119/8135	0.4575	0.8624	0.7789	TRADD/PLCB1/MAPK11/PPP2R3A/S1PR4/NRAS/MAPK13/PDPK1/ROCK2/PPP2CA/RAC1/PPP2R5C	12
KEGG	hsa04722	Neurotrophin signaling pathway	12/772	119/8135	0.4575	0.8624	0.7789	SH2B3/MAPK11/NRAS/NFKBIE/NTF3/GAB1/MAPK13/PDPK1/TP73/NFKBIA/CALM2/RAC1	12
KEGG	hsa05164	Influenza A	17/772	171/8135	0.4578	0.8624	0.7789	TRADD/SOCS3/FAS/FADD/SLC25A5/HLA-DPB1/HLA-DMB/HLA-DMA/NXF3/EP300/IL12A/NUP98/TPSAB1/NFKBIA/TNFRSF10B/RSAD2/IFNA17	17
KEGG	hsa04973	Carbohydrate digestion and absorption	5/772	47/8135	0.4649	0.8689	0.7848	PLCB1/SLC2A5/FXYD2/MGAM/SLC37A4	5
KEGG	hsa04664	Fc epsilon RI signaling pathway	7/772	68/8135	0.4699	0.8689	0.7848	MAPK11/VAV3/NRAS/MAPK13/PDPK1/SYK/RAC1	7
KEGG	hsa01250	Biosynthesis of nucleotide sugars	4/772	37/8135	0.4715	0.8689	0.7848	UGP2/GPI/NANS/CMAS	4
KEGG	hsa04211	Longevity regulating pathway	9/772	89/8135	0.4728	0.8689	0.7848	CREB1/SESN3/ADCY6/ADCY3/NRAS/IGF1R/PRKAG2/PPARG/APPL1	9
KEGG	hsa04650	Natural killer cell mediated cytotoxicity	13/772	131/8135	0.476	0.8689	0.7848	HLA-B/FAS/GZMB/VAV3/ARAF/NRAS/FCGR3B/TNFRSF10B/PPP3R1/SYK/ULBP3/RAC1/IFNA17	13
KEGG	hsa01040	Biosynthesis of unsaturated fatty acids	3/772	27/8135	0.4793	0.8689	0.7848	ELOVL7/FADS1/ACOT7	3
KEGG	hsa04621	NOD-like receptor signaling pathway	18/772	184/8135	0.4829	0.8689	0.7848	CAMP/DEFA4/TRIP6/PLCB1/FADD/MAPK11/HSP90AA1/GABARAPL2/BCL2L1/CXCL1/BIRC3/P2RX7/DEFA6/MAPK13/NFKBIA/GBP2/CASP4/IFNA17	18
KEGG	hsa04920	Adipocytokine signaling pathway	7/772	69/8135	0.4856	0.8689	0.7848	TRADD/SOCS3/CPT1C/NFKBIE/PRKAG2/NFKBIA/ACSL3	7
KEGG	hsa05031	Amphetamine addiction	7/772	69/8135	0.4856	0.8689	0.7848	CREB1/FOSB/SLC18A2/FOS/PPP3R1/CALM2/PPP1R1B	7
KEGG	hsa05340	Primary immunodeficiency	4/772	38/8135	0.4928	0.8689	0.7848	IL7R/JAK3/UNG/BLNK	4
KEGG	hsa04921	Oxytocin signaling pathway	15/772	154/8135	0.4981	0.8689	0.7848	MYL9/PLCB1/ADCY6/OXTR/ADCY3/CACNA2D2/NRAS/CACNA2D3/PRKAG2/FOS/ROCK2/PPP3R1/CALM2/KCNJ3/CDKN1A	15
KEGG	hsa05032	Morphine addiction	9/772	91/8135	0.5002	0.8689	0.7848	GNG11/ADCY6/PDE8B/ADCY3/SLC32A1/GABRP/GNG8/KCNJ3/PDE3A	9
KEGG	hsa04622	RIG-I-like receptor signaling pathway	7/772	70/8135	0.5012	0.8689	0.7848	TRADD/FADD/MAPK11/MAPK13/IL12A/NFKBIA/IFNA17	7
KEGG	hsa04672	Intestinal immune network for IgA production	5/772	49/8135	0.5025	0.8689	0.7848	IL2/HLA-DPB1/HLA-DMB/HLA-DMA/ITGA4	5
KEGG	hsa05030	Cocaine addiction	5/772	49/8135	0.5025	0.8689	0.7848	CREB1/FOSB/SLC18A2/DRD2/PPP1R1B	5
KEGG	hsa00650	Butanoate metabolism	3/772	28/8135	0.5042	0.8689	0.7848	ALDH5A1/GAD2/EHHADH	3
KEGG	hsa04725	Cholinergic synapse	11/772	113/8135	0.5117	0.8772	0.7923	GNG11/CREB1/PLCB1/ADCY6/ADCY3/CHRM4/CHAT/NRAS/GNG8/FOS/KCNJ3	11
KEGG	hsa04974	Protein digestion and absorption	10/772	103/8135	0.5191	0.8829	0.7974	SLC8A3/COL17A1/COL6A1/FXYD2/COL8A2/COL15A1/KCNK5/MME/COL13A1/COL10A1	10
KEGG	hsa00511	Other glycan degradation	2/772	18/8135	0.5204	0.8829	0.7974	HEXA/NEU1	2
KEGG	hsa04744	Phototransduction	3/772	29/8135	0.5284	0.8848	0.7991	GUCY2D/GRK7/CALM2	3
KEGG	hsa04064	NF-kappa B signaling pathway	10/772	104/8135	0.5318	0.8848	0.7991	TRADD/TRAF1/BCL2L1/CXCL1/BIRC3/EDA/IL1R1/NFKBIA/BLNK/SYK	10
KEGG	hsa04137	Mitophagy - animal	7/772	72/8135	0.532	0.8848	0.7991	OPTN/E2F1/GABARAPL2/BCL2L1/NRAS/FUNDC1/RPS27A	7
KEGG	hsa00260	Glycine, serine and threonine metabolism	4/772	40/8135	0.5342	0.8848	0.7991	ALAS2/ALAS1/AGXT2/GCAT	4
KEGG	hsa04726	Serotonergic synapse	11/772	115/8135	0.536	0.8848	0.7991	ALOX12/GNG11/HTR1B/PLCB1/ARAF/PTGS1/SLC6A4/NRAS/GNG8/SLC18A2/KCNJ3	11
KEGG	hsa00330	Arginine and proline metabolism	5/772	51/8135	0.539	0.8848	0.7991	ARG1/OAT/ARG2/P4HA1/AMD1	5
KEGG	hsa04213	Longevity regulating pathway - multiple species	6/772	62/8135	0.5432	0.8848	0.7991	ADCY6/ADCY3/NRAS/IGF1R/PRKAG2/HSPA1A	6
KEGG	hsa04910	Insulin signaling pathway	13/772	137/8135	0.5434	0.8848	0.7991	SOCS3/SOCS1/PRKAR2B/ARAF/NRAS/LIPE/SOCS2/PRKAG2/PDPK1/MKNK2/PRKCI/CALM2/RHOQ	13
KEGG	hsa04371	Apelin signaling pathway	13/772	139/8135	0.5653	0.9158	0.8271	GNG11/PLCB1/ADCY6/SLC8A3/MYL4/ADCY3/NRAS/LIPE/PRKAG2/GNG8/TFAM/MEF2D/CALM2	13
KEGG	hsa00052	Galactose metabolism	3/772	31/8135	0.5748	0.9265	0.8368	UGP2/GALM/MGAM	3
KEGG	hsa04666	Fc gamma R-mediated phagocytosis	9/772	97/8135	0.5797	0.9299	0.8399	WASF3/MARCKSL1/VAV3/ASAP2/FCGR3B/LIMK2/WASF1/SYK/RAC1	9
KEGG	hsa00071	Fatty acid degradation	4/772	43/8135	0.593	0.9465	0.8548	CPT1C/CYP2U1/EHHADH/ACSL3	4
KEGG	hsa04136	Autophagy - other	3/772	32/8135	0.5969	0.9469	0.8552	ULK2/GABARAPL2/PPP2CA	3
KEGG	hsa05022	Pathways of neurodegeneration - multiple diseases	44/772	476/8135	0.5993	0.9469	0.8552	TUBB1/DNAH17/TUBA1A/SNCA/OPTN/PLCB1/FAS/FADD/MAPK11/CSF1/KIF5C/NEFL/SLC25A5/ARAF/ULK2/BCL2L1/DNAH8/NRAS/PSMD14/PSMD12/NDUFA10/DNAI2/NDUFB2/HIP1/DCTN4/PARK7/CAPN2/MAPK13/NEFH/CSNK1A1/DERL1/VCP/PPP3R1/DKK4/APC/CALM2/PPID/ATXN2L/RPS27A/UBA1/NDUFV2/TUBB6/RAC1/C9orf72	44
KEGG	hsa04020	Calcium signaling pathway	22/772	240/8135	0.602	0.9469	0.8552	VEGFC/EGF/MCOLN3/PLCB1/PDGFA/OXTR/SLC8A3/SLC25A5/ADCY3/P2RX7/TNNC1/P2RX3/FGFR2/RET/TBXA2R/CYSLTR2/GNAL/TNNC2/PPP3R1/CALM2/P2RX6/ERBB3	22
KEGG	hsa04976	Bile secretion	8/772	89/8135	0.6179	0.9469	0.8552	ADCY6/FXYD2/ADCY3/CA2/SCT/ABCG2/SLC27A5/ABCC4	8
KEGG	hsa04934	Cushing syndrome	14/772	155/8135	0.6186	0.9469	0.8552	PBX1/CREB1/CDKN2A/PLCB1/ADCY6/PDE8B/ADCY3/E2F1/CYP21A2/CCNE1/TCF7L1/APC/CDKN1A/CRH	14
KEGG	hsa04720	Long-term potentiation	6/772	67/8135	0.6211	0.9469	0.8552	PLCB1/ARAF/NRAS/EP300/PPP3R1/CALM2	6
KEGG	hsa04340	Hedgehog signaling pathway	5/772	56/8135	0.6243	0.9469	0.8552	EVC/CSNK1A1/CSNK1G3/SPOPL/IHH	5
KEGG	hsa04923	Regulation of lipolysis in adipocytes	5/772	56/8135	0.6243	0.9469	0.8552	MGLL/ADCY6/ADCY3/PTGS1/LIPE	5
KEGG	hsa04014	Ras signaling pathway	21/772	232/8135	0.625	0.9469	0.8552	VEGFC/EGF/GNG11/KSR2/PDGFA/CSF1/BCL2L1/NRAS/RASSF1/NTF3/GAB1/FGFR2/IGF1R/TIAM1/REL/GNG8/EPHA2/RALBP1/NF1/CALM2/RAC1	21
KEGG	hsa04310	Wnt signaling pathway	15/772	167/8135	0.6288	0.9469	0.8552	SERPINF1/PLCB1/MYC/EP300/TCF7L1/CSNK1A1/CTNNBIP1/TLE1/ROCK2/PPP3R1/DKK4/APC/RUVBL1/RAC1/DAAM2	15
KEGG	hsa04916	Melanogenesis	9/772	101/8135	0.6294	0.9469	0.8552	CREB1/PLCB1/ADCY6/ASIP/ADCY3/NRAS/EP300/TCF7L1/CALM2	9
KEGG	hsa03022	Basal transcription factors	4/772	45/8135	0.6297	0.9469	0.8552	GTF2IRD1/GTF2E1/TAF4/TAF7L	4
KEGG	hsa00920	Sulfur metabolism	1/772	10/8135	0.6313	0.9469	0.8552	SELENBP1	1
KEGG	hsa05322	Systemic lupus erythematosus	12/772	136/8135	0.6488	0.9591	0.8662	CTSG/ELANE/C1QA/TRIM21/HLA-DPB1/HLA-DMB/FCGR3B/C3/HLA-DMA/C8G/C1QB/ACTN1	12
KEGG	hsa04724	Glutamatergic synapse	10/772	114/8135	0.6511	0.9591	0.8662	GNG11/PLCB1/ADCY6/ADCY3/HOMER2/GRM4/SHANK1/GNG8/PPP3R1/KCNJ3	10
KEGG	hsa00480	Glutathione metabolism	5/772	58/8135	0.6557	0.9591	0.8662	GGT1/NAT8B/RRM2/GSTT1/LANCL1	5
KEGG	hsa03060	Protein export	2/772	23/8135	0.6561	0.9591	0.8662	SEC61B/SEC62	2
KEGG	hsa05131	Shigellosis	22/772	247/8135	0.657	0.9591	0.8662	MYL9/TRADD/CTTN/PLCB1/MAPK11/BCL2L1/TIFA/ELMO2/C3/CAPN2/IL1R1/MAPK13/NFKBIA/CASP4/ROCK2/ACTN1/FNBP1L/WASF1/PPID/RPS27A/RAC1/CD44	22
KEGG	hsa00130	Ubiquinone and other terpenoid-quinone biosynthesis	1/772	11/8135	0.6663	0.9591	0.8662	GGCX	1
KEGG	hsa04912	GnRH signaling pathway	8/772	93/8135	0.6677	0.9591	0.8662	PLCB1/ADCY6/MAPK11/ADCY3/NRAS/MAPK13/GNRHR/CALM2	8
KEGG	hsa04330	Notch signaling pathway	5/772	59/8135	0.6707	0.9591	0.8662	NOTCH2/EP300/HEY2/TLE1/HES1	5
KEGG	hsa04370	VEGF signaling pathway	5/772	59/8135	0.6707	0.9591	0.8662	MAPK11/NRAS/MAPK13/PPP3R1/RAC1	5
KEGG	hsa04146	Peroxisome	7/772	82/8135	0.6719	0.9591	0.8662	SLC27A2/PHYH/NUDT12/EHHADH/PEX13/PEX11B/ACSL3	7
KEGG	hsa03030	DNA replication	3/772	36/8135	0.6775	0.9591	0.8662	MCM2/RFC1/POLE2	3
KEGG	hsa04977	Vitamin digestion and absorption	2/772	24/8135	0.6792	0.9591	0.8662	SLC23A1/LMBRD1	2
KEGG	hsa05416	Viral myocarditis	5/772	60/8135	0.6853	0.9591	0.8662	HLA-B/HLA-DPB1/HLA-DMB/HLA-DMA/RAC1	5
KEGG	hsa00565	Ether lipid metabolism	4/772	49/8135	0.6964	0.9591	0.8662	PLD4/GDPD1/TMEM86B/PAFAH2	4
KEGG	hsa04922	Glucagon signaling pathway	9/772	107/8135	0.6976	0.9591	0.8662	CREB1/PLCB1/CPT1C/SIK2/EP300/PRKAG2/PPP3R1/CALM2/LDHC	9
KEGG	hsa01240	Biosynthesis of cofactors	13/772	153/8135	0.7043	0.9591	0.8662	ALAS2/UGP2/ALAS1/GGCX/UROD/ADSL/FECH/OXSM/ALPL/ALAD/NMNAT1/KMO/TPK1	13
KEGG	hsa04931	Insulin resistance	9/772	108/8135	0.7081	0.9591	0.8662	SOCS3/CREB1/SLC27A2/MLXIP/PRKAG2/SLC27A1/PDPK1/SLC27A5/NFKBIA	9
KEGG	hsa01232	Nucleotide metabolism	7/772	85/8135	0.7084	0.9591	0.8662	GMPR/ENPP3/AMPD3/ADSL/RRM2/TK1/NT5DC4	7
KEGG	hsa05110	Vibrio cholerae infection	4/772	50/8135	0.7116	0.9591	0.8662	SEC61B/ATP6V0A2/ADCY3/ATP6V1E1	4
KEGG	hsa04066	HIF-1 signaling pathway	9/772	109/8135	0.7185	0.9591	0.8662	EGF/EP300/IGF1R/ENO2/MKNK2/EPO/ALDOB/LDHC/CDKN1A	9
KEGG	hsa04742	Taste transduction	7/772	86/8135	0.7199	0.9591	0.8662	HTR1B/PLCB1/ADCY6/SCN9A/GRM4/P2RX3/KCNK5	7
KEGG	hsa00790	Folate biosynthesis	2/772	26/8135	0.7216	0.9591	0.8662	AKR1C3/ALPL	2
KEGG	hsa04950	Maturity onset diabetes of the young	2/772	26/8135	0.7216	0.9591	0.8662	HHEX/HES1	2
KEGG	hsa04932	Non-alcoholic fatty liver disease	13/772	155/8135	0.7218	0.9591	0.8662	SOCS3/FAS/MAPK11/MLXIP/NDUFA10/NDUFB2/MAPK13/PRKAG2/CEBPA/PPARG/FOS/NDUFV2/RAC1	13
KEGG	hsa00564	Glycerophospholipid metabolism	8/772	98/8135	0.7241	0.9591	0.8662	PGS1/PLD4/PCYT1B/MBOAT2/CHAT/GPD1/LPIN2/DGKA	8
KEGG	hsa00270	Cysteine and methionine metabolism	4/772	51/8135	0.7263	0.9591	0.8662	AGXT2/IL4I1/AMD1/LDHC	4
KEGG	hsa04913	Ovarian steroidogenesis	4/772	51/8135	0.7263	0.9591	0.8662	ADCY6/ADCY3/IGF1R/AKR1C3	4
KEGG	hsa05217	Basal cell carcinoma	5/772	63/8135	0.7264	0.9591	0.8662	POLK/DDB2/TCF7L1/APC/CDKN1A	5
KEGG	hsa00513	Various types of N-glycan biosynthesis	3/772	39/8135	0.7297	0.9591	0.8662	HEXA/B4GALNT4/DDOST	3
KEGG	hsa04150	mTOR signaling pathway	13/772	156/8135	0.7303	0.9591	0.8662	FLCN/ULK2/STRADB/NRAS/NPRL3/DDIT4/GRB10/IGF1R/MAPKAP1/ATP6V1E1/PDPK1/FNIP2/LPIN2	13
KEGG	hsa04260	Cardiac muscle contraction	7/772	87/8135	0.7311	0.9591	0.8662	SLC8A3/TPM1/MYL4/FXYD2/CACNA2D2/TNNC1/CACNA2D3	7
KEGG	hsa04270	Vascular smooth muscle contraction	11/772	134/8135	0.7377	0.9603	0.8674	MYL9/PLCB1/EDN3/ADCY6/MYH11/ARAF/ADCY3/NPPB/CALD1/ROCK2/CALM2	11
KEGG	hsa04971	Gastric acid secretion	6/772	76/8135	0.74	0.9603	0.8674	KCNJ15/PLCB1/ADCY6/ADCY3/CA2/CALM2	6
KEGG	hsa00062	Fatty acid elongation	2/772	27/8135	0.741	0.9603	0.8674	ELOVL7/ACOT7	2
KEGG	hsa04933	AGE-RAGE signaling pathway in diabetic complications	8/772	100/8135	0.7448	0.9614	0.8683	VEGFC/TGFB2/PLCB1/PIM1/MAPK11/NRAS/MAPK13/RAC1	8
KEGG	hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	1/772	14/8135	0.7527	0.9665	0.873	CHST1	1
KEGG	hsa04217	Necroptosis	13/772	159/8135	0.7547	0.9665	0.873	TRADD/FAS/FADD/HSP90AA1/SLC25A5/BIRC3/CAPN2/JAK3/GLUD2/TNFRSF10B/PPID/CHMP1B/IFNA17	13
KEGG	hsa05135	Yersinia infection	11/772	137/8135	0.7634	0.9738	0.8796	IL2/MAPK11/VAV3/ELMO2/MAPK13/ITGA4/NFKBIA/FOS/ROCK2/RAC1/WIPF1	11
KEGG	hsa00010	Glycolysis / Gluconeogenesis	5/772	67/8135	0.775	0.9804	0.8855	GALM/GPI/ENO2/ALDOB/LDHC	5
KEGG	hsa00380	Tryptophan metabolism	3/772	42/8135	0.775	0.9804	0.8855	IL4I1/EHHADH/KMO	3
KEGG	hsa05206	MicroRNAs in cancer	26/772	310/8135	0.7777	0.9804	0.8855	ITGB3/CDKN2A/TGFB2/SOCS1/PIM1/PDGFA/MIR21/MYC/TPM1/SOX4/NOTCH2/E2F1/MMP9/NRAS/RASSF1/CDCA5/BMPR2/DDIT4/EP300/CCNE1/APC/CDC25C/SLC45A3/CD44/CDKN1A/ERBB3	26
KEGG	hsa04620	Toll-like receptor signaling pathway	8/772	104/8135	0.7829	0.9819	0.8868	FADD/MAPK11/MAPK13/IL12A/NFKBIA/FOS/RAC1/IFNA17	8
KEGG	hsa04714	Thermogenesis	19/772	232/8135	0.7849	0.9819	0.8868	MGLL/CREB1/ADCY6/MAPK11/CPT1C/ADCY3/NRAS/NDUFA10/NPPB/NDUFB2/LIPE/MAPK13/PRDM16/ARID1A/PRKAG2/PPARG/COX17/NDUFV2/ACSL3	19
KEGG	hsa00030	Pentose phosphate pathway	2/772	30/8135	0.7923	0.9862	0.8907	GPI/ALDOB	2
KEGG	hsa04140	Autophagy - animal	11/772	141/8135	0.795	0.9862	0.8907	EIF2AK4/ULK2/GABARAPL2/BCL2L1/DAPK2/NRAS/DDIT4/IGF1R/PDPK1/PPP2CA/C9orf72	11
KEGG	hsa00360	Phenylalanine metabolism	1/772	16/8135	0.7975	0.9862	0.8907	IL4I1	1
KEGG	hsa05168	Herpes simplex virus 1 infection	42/772	495/8135	0.8056	0.987	0.8914	TRADD/EIF2AK4/ITGB3/SOCS3/HLA-B/ZNF302/FAS/FADD/ZNF354B/BCL2L1/HLA-DPB1/BIRC3/ZNF473/HLA-DMB/ZNF19/C3/ZNF333/HLA-DMA/NXF3/ZNF584/ZFP57/IL12A/ZNF823/ZNF324/ZNF517/NFKBIA/ZNF212/ZNF763/ZNF546/ZNF620/ZNF589/SYK/ZNF610/POU2F2/ZNF701/CALR/IFNA17/ZNF791/ZNF717/ZNF79/ZNF554/ZNF606	42
KEGG	hsa05230	Central carbon metabolism in cancer	5/772	70/8135	0.8069	0.987	0.8914	MYC/NRAS/FGFR2/RET/LDHC	5
KEGG	hsa00410	beta-Alanine metabolism	2/772	31/8135	0.8073	0.987	0.8914	GAD2/EHHADH	2
KEGG	hsa00240	Pyrimidine metabolism	4/772	58/8135	0.8137	0.987	0.8914	ENPP3/RRM2/TK1/NT5DC4	4
KEGG	hsa00120	Primary bile acid biosynthesis	1/772	17/8135	0.8167	0.987	0.8914	SLC27A5	1
KEGG	hsa05014	Amyotrophic lateral sclerosis	30/772	364/8135	0.8212	0.987	0.8914	TUBB1/DNAH17/TUBA1A/OPTN/MAPK11/NRG4/KIF5C/NEFL/ULK2/BCL2L1/DNAH8/PSMD14/PSMD12/NDUFA10/DNAI2/NDUFB2/DCTN4/NXF3/MAPK13/POM121/NUP98/NEFH/DERL1/VCP/PPP3R1/ATXN2L/NDUFV2/TUBB6/RAC1/C9orf72	30
KEGG	hsa00640	Propanoate metabolism	2/772	32/8135	0.8214	0.987	0.8914	EHHADH/LDHC	2
KEGG	hsa04919	Thyroid hormone signaling pathway	9/772	121/8135	0.8234	0.987	0.8914	ITGB3/PLCB1/MYC/FXYD2/NOTCH2/NRAS/EP300/NCOA3/PDPK1	9
KEGG	hsa04930	Type II diabetes mellitus	3/772	46/8135	0.8256	0.987	0.8914	SOCS3/SOCS1/SOCS2	3
KEGG	hsa04925	Aldosterone synthesis and secretion	7/772	98/8135	0.8342	0.9892	0.8934	CREB1/PLCB1/ADCY6/ADCY3/LIPE/CYP21A2/CALM2	7
KEGG	hsa00051	Fructose and mannose metabolism	2/772	33/8135	0.8345	0.9892	0.8934	ALDOB/ENOSF1	2
KEGG	hsa00514	Other types of O-glycan biosynthesis	3/772	47/8135	0.8366	0.9892	0.8934	GALNT14/GALNT6/GALNT9	3
KEGG	hsa00561	Glycerolipid metabolism	4/772	61/8135	0.8435	0.9938	0.8976	MGLL/MBOAT2/LPIN2/DGKA	4
KEGG	hsa00280	Valine, leucine and isoleucine degradation	3/772	48/8135	0.847	0.9943	0.898	AGXT2/IL4I1/EHHADH	3
KEGG	hsa03250	Viral life cycle - HIV-1	4/772	63/8135	0.861	1	0.9032	SERINC3/FEZ1/EP300/CCNT2	4
KEGG	hsa04972	Pancreatic secretion	7/772	102/8135	0.8628	1	0.9032	PLCB1/ADCY6/FXYD2/ADCY3/CA2/SCT/RAC1	7
KEGG	hsa00670	One carbon pool by folate	1/772	20/8135	0.8642	1	0.9032	ATIC	1
KEGG	hsa05020	Prion disease	21/772	273/8135	0.874	1	0.9032	TUBB1/TUBA1A/CAV2/CREB1/C1QA/MAPK11/KIF5C/SLC25A5/PSMD14/PSMD12/NDUFA10/NDUFB2/C8G/MAPK13/C1QB/PPP3R1/NCF4/NDUFV2/TUBB6/RAC1/HSPA1A	21
KEGG	hsa00770	Pantothenate and CoA biosynthesis	1/772	21/8135	0.8771	1	0.9032	ENPP3	1
KEGG	hsa04960	Aldosterone-regulated sodium reabsorption	2/772	37/8135	0.8786	1	0.9032	FXYD2/PDPK1	2
KEGG	hsa04970	Salivary secretion	6/772	93/8135	0.8869	1	0.9032	CAMP/PLCB1/ADCY6/FXYD2/ADCY3/CALM2	6
KEGG	hsa00983	Drug metabolism - other enzymes	5/772	80/8135	0.8879	1	0.9032	MPO/TPMT/RRM2/TK1/GSTT1	5
KEGG	hsa00340	Histidine metabolism	1/772	22/8135	0.8888	1	0.9032	HDC	1
KEGG	hsa00900	Terpenoid backbone biosynthesis	1/772	22/8135	0.8888	1	0.9032	NUS1	1
KEGG	hsa05012	Parkinson disease	20/772	266/8135	0.8921	1	0.9032	TUBB1/TUBA1A/SNCA/KIF5C/SLC25A5/BCL2L1/PSMD14/PSMD12/NDUFA10/NDUFB2/PARK7/GNAL/SLC18A2/CALM2/KEAP1/RPS27A/UBA1/DRD2/NDUFV2/TUBB6	20
KEGG	hsa05033	Nicotine addiction	2/772	40/8135	0.9043	1	0.9032	SLC32A1/GABRP	2
KEGG	hsa05016	Huntington disease	23/772	306/8135	0.9067	1	0.9032	TUBB1/DNAH17/TUBA1A/CREB1/PLCB1/KIF5C/SLC25A5/ULK2/DNAH8/CLTA/PSMD14/PSMD12/NDUFA10/DNAI2/NDUFB2/HIP1/DCTN4/EP300/TAF4/PPARG/TFAM/NDUFV2/TUBB6	23
KEGG	hsa05208	Chemical carcinogenesis - reactive oxygen species	16/772	223/8135	0.9096	1	0.9032	EGF/MAPK11/SLC25A5/ARAF/NRAS/NDUFA10/NDUFB2/MAPK13/AKR1C3/GSTT1/PDPK1/NFKBIA/FOS/KEAP1/NDUFV2/RAC1	16
KEGG	hsa04911	Insulin secretion	5/772	86/8135	0.9209	1	0.9032	CREB1/PLCB1/ADCY6/FXYD2/ADCY3	5
KEGG	hsa00562	Inositol phosphate metabolism	4/772	73/8135	0.9255	1	0.9032	PLCB1/INPP4B/INPP5F/ISYNA1	4
KEGG	hsa04978	Mineral absorption	3/772	60/8135	0.9332	1	0.9032	SLC8A3/FXYD2/SLC30A1	3
KEGG	hsa01230	Biosynthesis of amino acids	4/772	75/8135	0.9346	1	0.9032	ARG1/ARG2/ENO2/ALDOB	4
KEGG	hsa05017	Spinocerebellar ataxia	9/772	143/8135	0.935	1	0.9032	PLCB1/VLDLR/SLC25A5/ULK2/PSMD14/PSMD12/DAB1/NFYA/ATXN2L	9
KEGG	hsa00140	Steroid hormone biosynthesis	3/772	61/8135	0.9379	1	0.9032	HSD11B1/CYP21A2/AKR1C3	3
KEGG	hsa03050	Proteasome	2/772	46/8135	0.9412	1	0.9032	PSMD14/PSMD12	2
KEGG	hsa00620	Pyruvate metabolism	2/772	47/8135	0.9458	1	0.9032	HAGH/LDHC	2
KEGG	hsa04623	Cytosolic DNA-sensing pathway	3/772	63/8135	0.9463	1	0.9032	NFKBIA/POLR3G/IFNA17	3
KEGG	hsa05207	Chemical carcinogenesis - receptor activation	14/772	212/8135	0.9481	1	0.9032	EGF/CREB1/KLF4/ADCY6/MYC/HSP90AA1/NOTCH2/ADCY3/E2F1/NRAS/GSTT1/FOS/HSP90B1/BIRC5	14
KEGG	hsa04929	GnRH secretion	3/772	64/8135	0.9501	1	0.9032	PLCB1/NRAS/KCNJ3	3
KEGG	hsa03013	Nucleocytoplasmic transport	6/772	108/8135	0.9512	1	0.9032	CASC3/NXF3/IPO7/POM121/NUP98/XPO6	6
KEGG	hsa04070	Phosphatidylinositol signaling system	5/772	97/8135	0.9598	1	0.9032	PLCB1/INPP4B/INPP5F/CALM2/DGKA	5
KEGG	hsa00600	Sphingolipid metabolism	2/772	52/8135	0.9643	1	0.9032	HEXA/NEU1	2
KEGG	hsa00040	Pentose and glucuronate interconversions	1/772	34/8135	0.9665	1	0.9032	UGP2	1
KEGG	hsa03020	RNA polymerase	1/772	34/8135	0.9665	1	0.9032	POLR3G	1
KEGG	hsa05034	Alcoholism	11/772	187/8135	0.973	1	0.9032	GNG11/CREB1/ARAF/FOSB/NRAS/GNG8/SLC18A2/CALM2/DRD2/PPP1R1B/CRH	11
KEGG	hsa05010	Alzheimer disease	26/772	384/8135	0.9785	1	0.9032	TUBB1/TUBA1A/SNCA/PLCB1/FAS/FADD/CSF1/KIF5C/SLC25A5/ARAF/ULK2/NRAS/PSMD14/PSMD12/NDUFA10/NDUFB2/CAPN2/MME/CSNK1A1/PPP3R1/DKK4/APC/CALM2/PPID/NDUFV2/TUBB6	26
KEGG	hsa03008	Ribosome biogenesis in eukaryotes	5/772	109/8135	0.9817	1	0.9032	EMG1/NXF3/FBLL1/REXO2/POP4	5
KEGG	hsa00980	Metabolism of xenobiotics by cytochrome P450	3/772	78/8135	0.9827	1	0.9032	CBR3/HSD11B1/GSTT1	3
KEGG	hsa04216	Ferroptosis	1/772	41/8135	0.9834	1	0.9032	ACSL3	1
KEGG	hsa03010	Ribosome	8/772	158/8135	0.9864	1	0.9032	RPS26/MRPL35/RPS27/RPS28/RPS15/RPS21/RPS27A/RPL18	8
KEGG	hsa04975	Fat digestion and absorption	1/772	43/8135	0.9864	1	0.9032	SLC27A1	1
KEGG	hsa05415	Diabetic cardiomyopathy	11/772	203/8135	0.9884	1	0.9032	TGFB2/PLCB1/MAPK11/SLC25A5/MMP9/NDUFA10/NDUFB2/MAPK13/NCF4/NDUFV2/RAC1	11
KEGG	hsa03040	Spliceosome	7/772	147/8135	0.9891	1	0.9032	PPIL1/SF3B4/TRA2B/ZMAT2/RBM22/SF3B5/HSPA1A	7
KEGG	hsa00190	Oxidative phosphorylation	6/772	134/8135	0.9904	1	0.9032	ATP6V0A2/NDUFA10/NDUFB2/ATP6V1E1/COX17/NDUFV2	6
KEGG	hsa00830	Retinol metabolism	2/772	68/8135	0.991	1	0.9032	CYP26B1/DHRS9	2
KEGG	hsa05204	Chemical carcinogenesis - DNA adducts	2/772	69/8135	0.9917	1	0.9032	HSD11B1/GSTT1	2
KEGG	hsa00510	N-Glycan biosynthesis	1/772	50/8135	0.9933	1	0.9032	DDOST	1
KEGG	hsa04979	Cholesterol metabolism	1/772	50/8135	0.9933	1	0.9032	LIPA	1
KEGG	hsa01200	Carbon metabolism	4/772	115/8135	0.9963	1	0.9032	GPI/ENO2/GLUD2/ALDOB	4
KEGG	hsa00970	Aminoacyl-tRNA biosynthesis	1/772	66/8135	0.9987	1	0.9032	RARS2	1
KEGG	hsa00982	Drug metabolism - cytochrome P450	1/772	72/8135	0.9993	1	0.9032	GSTT1	1
KEGG	hsa04740	Olfactory transduction	9/772	440/8135	1	1	0.9032	GUCY2D/OR2W3/SLC8A3/ADCY3/OR2F1/GNAL/OR6B1/OR51B4/CALM2	9