ONTOLOGY	ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	qvalue	geneID	Count
KEGG	hsa04142	Lysosome	13/390	132/8135	0.01051	0.8203	0.8203	NPC1/ACP5/PPT2/AP1B1/HEXA/SCARB2/NAGA/NEU1/CD63/CD164/ARSG/ATP6AP1/ASAH1	13
KEGG	hsa05010	Alzheimer disease	28/390	384/8135	0.0171	0.8203	0.8203	NDUFA13/APC/NDUFV2/CSNK2A3/PSMD9/SLC39A7/GRIN2D/PSMB2/FZD8/SLC39A11/NDUFB11/NDUFB3/HRAS/TUBA8/VDAC2/RTN4/VDAC1/CSNK2A1/APH1A/CAPN2/AKT2/NDUFB7/LRP5/CSNK1A1/NDUFA4/CASP8/FAS/ATP5PD	28
KEGG	hsa04062	Chemokine signaling pathway	16/390	192/8135	0.02182	0.8203	0.8203	ADCY9/PPBP/XCL1/CX3CL1/PF4V1/ARRB1/ROCK2/HRAS/PF4/GRK5/XCR1/XCL2/AKT2/ADCY7/GNG11/GRK3	16
KEGG	hsa05163	Human cytomegalovirus infection	18/390	225/8135	0.02262	0.8203	0.8203	ADCY9/CALR/CGAS/IL10RA/CX3CL1/IFNA1/ROCK2/CDK4/GNAS/HRAS/E2F2/PRKCG/AKT2/ADCY7/GNG11/CASP8/FAS/TAP1	18
KEGG	hsa00514	Other types of O-glycan biosynthesis	6/390	47/8135	0.02379	0.8203	0.8203	RFNG/GALNT2/GALNT14/GALNT8/PLOD3/POFUT1	6
KEGG	hsa04976	Bile secretion	9/390	89/8135	0.02625	0.8203	0.8203	ADCY9/UGT1A9/GNAS/UGT1A1/ABCB4/UGT2A1/ADCY7/LDLR/SCT	9
KEGG	hsa00760	Nicotinate and nicotinamide metabolism	5/390	36/8135	0.02735	0.8203	0.8203	NMRK1/NNT/NT5M/NADK2/ENPP3	5
KEGG	hsa05032	Morphine addiction	9/390	91/8135	0.0298	0.8203	0.8203	ADCY9/GABBR1/ARRB1/GNAS/GRK5/PRKCG/ADCY7/GNG11/GRK3	9
KEGG	hsa05143	African trypanosomiasis	5/390	37/8135	0.03042	0.8203	0.8203	HPR/PRKCG/APOL1/FAS/IL18	5
KEGG	hsa04611	Platelet activation	11/390	124/8135	0.03531	0.8203	0.8203	ADCY9/GP9/GUCY1B1/TBXA2R/BTK/ROCK2/PTGS1/GNAS/GP1BA/AKT2/ADCY7	11
KEGG	hsa05165	Human papillomavirus infection	23/390	331/8135	0.04632	0.8203	0.8203	ISG15/RFNG/ITGA4/APC/LAMC2/ITGB5/TCF7/IFNA1/FZD8/TRAF3/CDK4/GNAS/HRAS/HEY1/HES1/AKT2/PARD6A/CSNK1A1/COMP/CASP8/FAS/ATP6AP1/PPP2R5D	23
KEGG	hsa05170	Human immunodeficiency virus 1 infection	16/390	212/8135	0.04794	0.8203	0.8203	CALR/CGAS/ELOB/AP1B1/IFNA1/APOBEC3G/HRAS/APOBEC3D/PRKCG/AKT2/GNG11/SAMHD1/CASP8/FAS/TAP1/PAK4	16
KEGG	hsa05224	Breast cancer	12/390	147/8135	0.04945	0.8203	0.8203	APC/TCF7/FZD8/CDK4/HRAS/E2F2/HEY1/HES1/AKT2/LRP5/CSNK1A1/FGF17	12
KEGG	hsa04061	Viral protein interaction with cytokine and cytokine receptor	9/390	100/8135	0.0499	0.8203	0.8203	PPBP/IL10RA/XCL1/CX3CL1/PF4V1/PF4/XCR1/XCL2/IL18	9
KEGG	hsa04923	Regulation of lipolysis in adipocytes	6/390	56/8135	0.0504	0.8203	0.8203	ADCY9/PTGS1/GNAS/MGLL/AKT2/ADCY7	6
KEGG	hsa05226	Gastric cancer	12/390	149/8135	0.0538	0.8203	0.8203	APC/TCF7/MLH1/FZD8/HRAS/E2F2/GAB1/AKT2/LRP5/CSNK1A1/CDH1/FGF17	12
KEGG	hsa05213	Endometrial cancer	6/390	58/8135	0.05808	0.8203	0.8203	APC/TCF7/MLH1/HRAS/AKT2/CDH1	6
KEGG	hsa05169	Epstein-Barr virus infection	15/390	202/8135	0.06084	0.8203	0.8203	ISG15/CALR/BTK/HLA-DPA1/VIM/IFNA1/TRAF3/CDK4/E2F2/HES1/ENTPD3/AKT2/CASP8/FAS/TAP1	15
KEGG	hsa04330	Notch signaling pathway	6/390	59/8135	0.06217	0.8203	0.8203	RFNG/PTCRA/HEY1/HES1/APH1A/KAT2B	6
KEGG	hsa05164	Influenza A	13/390	171/8135	0.06679	0.8203	0.8203	PRSS1/HLA-DPA1/IFNA1/TRAF3/CDK4/VDAC1/KPNA2/CPSF4L/AKT2/KPNA7/CASP8/FAS/IL18	13
KEGG	hsa03013	Nucleocytoplasmic transport	9/390	108/8135	0.07395	0.8203	0.8203	IPO4/CASC3/RANBP17/XPO7/EEF1A2/POM121/ACIN1/KPNA2/KPNA7	9
KEGG	hsa00040	Pentose and glucuronate interconversions	4/390	34/8135	0.07777	0.8203	0.8203	UGT1A9/CRYL1/UGT1A1/UGT2A1	4
KEGG	hsa04929	GnRH secretion	6/390	64/8135	0.08511	0.8203	0.8203	GABBR1/ARRB1/HRAS/PRKCG/AKT2/TRPC5	6
KEGG	hsa05414	Dilated cardiomyopathy	8/390	96/8135	0.08887	0.8203	0.8203	ADCY9/ITGA4/ITGB5/EMD/GNAS/SLC8A3/ACTC1/ADCY7	8
KEGG	hsa04614	Renin-angiotensin system	3/390	23/8135	0.0953	0.8203	0.8203	MAS1/ACE/CMA1	3
KEGG	hsa04724	Glutamatergic synapse	9/390	114/8135	0.096	0.8203	0.8203	ADCY9/SLC1A3/GRIN2D/GNAS/PRKCG/GRIK5/ADCY7/GNG11/GRK3	9
KEGG	hsa04360	Axon guidance	13/390	182/8135	0.0974	0.8203	0.8203	NEO1/EPHB3/DPYSL2/ROCK2/ROBO3/HRAS/DCC/MYL9/PARD6A/ABL1/NRP1/TRPC5/PAK4	13
KEGG	hsa04723	Retrograde endocannabinoid signaling	11/390	148/8135	0.09816	0.8203	0.8203	NDUFA13/ADCY9/NDUFV2/NDUFB11/NDUFB3/PRKCG/MGLL/NDUFB7/ADCY7/GNG11/NDUFA4	11
KEGG	hsa04510	Focal adhesion	14/390	201/8135	0.1024	0.8203	0.8203	ITGA4/RAPGEF1/LAMC2/ITGB5/ROCK2/HRAS/VEGFB/PRKCG/CAPN2/AKT2/MYL9/COMP/PARVB/PAK4	14
KEGG	hsa04310	Wnt signaling pathway	12/390	167/8135	0.1048	0.8203	0.8203	APC/CSNK2A3/TCF7/ROCK2/FZD8/NOTUM/SFRP2/CSNK2A1/PRKCG/LRP5/MMP7/CSNK1A1	12
KEGG	hsa00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	3/390	24/8135	0.1052	0.8203	0.8203	HS3ST3A1/EXT2/NDST2	3
KEGG	hsa05225	Hepatocellular carcinoma	12/390	168/8135	0.1082	0.8203	0.8203	APC/TCF7/FZD8/CDK4/HRAS/E2F2/GAB1/PRKCG/SMARCE1/AKT2/LRP5/CSNK1A1	12
KEGG	hsa05415	Diabetic cardiomyopathy	14/390	203/8135	0.1086	0.8203	0.8203	NDUFA13/NDUFV2/PDK4/NDUFB11/ACE/NDUFB3/VDAC2/VDAC1/CMA1/PRKCG/AKT2/NDUFB7/NDUFA4/ATP5PD	14
KEGG	hsa05211	Renal cell carcinoma	6/390	69/8135	0.1121	0.8203	0.8203	RAPGEF1/ELOB/HRAS/GAB1/AKT2/PAK4	6
KEGG	hsa04012	ErbB signaling pathway	7/390	85/8135	0.1124	0.8203	0.8203	HRAS/GAB1/PRKCG/ERBB3/AKT2/ABL1/PAK4	7
KEGG	hsa04972	Pancreatic secretion	8/390	102/8135	0.1156	0.8203	0.8203	ADCY9/PRSS1/RAB27B/GNAS/PLA2G12A/PRKCG/ADCY7/SCT	8
KEGG	hsa04210	Apoptosis	10/390	136/8135	0.1172	0.8203	0.8203	SPTA1/PARP2/HRAS/TUBA8/PARP4/CAPN2/AKT2/CASP8/FAS/PRF1	10
KEGG	hsa04540	Gap junction	7/390	88/8135	0.1285	0.8203	0.8203	ADCY9/GUCY1B1/GNAS/HRAS/TUBA8/PRKCG/ADCY7	7
KEGG	hsa04340	Hedgehog signaling pathway	5/390	56/8135	0.1293	0.8203	0.8203	ARRB1/GLI2/GAS1/GRK3/CSNK1A1	5
KEGG	hsa04371	Apelin signaling pathway	10/390	139/8135	0.13	0.8203	0.8203	ADCY9/HRAS/SLC8A3/PRKAB1/AKT2/ADCY7/GNG11/CDH1/MEF2C/MYL4	10
KEGG	hsa05218	Melanoma	6/390	72/8135	0.1302	0.8203	0.8203	CDK4/HRAS/E2F2/AKT2/CDH1/FGF17	6
KEGG	hsa05219	Bladder cancer	4/390	41/8135	0.1316	0.8203	0.8203	CDK4/HRAS/E2F2/CDH1	4
KEGG	hsa04928	Parathyroid hormone synthesis, secretion and action	8/390	106/8135	0.1355	0.8203	0.8203	ADCY9/BGLAP/ARRB1/GNAS/PRKCG/LRP5/ADCY7/MEF2C	8
KEGG	hsa00562	Inositol phosphate metabolism	6/390	73/8135	0.1365	0.8203	0.8203	PI4KB/FIG4/OCRL/INPP4A/TPI1/IPPK	6
KEGG	hsa00062	Fatty acid elongation	3/390	27/8135	0.1372	0.8203	0.8203	PPT2/ACOT7/HACD1	3
KEGG	hsa05207	Chemical carcinogenesis - receptor activation	14/390	212/8135	0.1395	0.8203	0.8203	ADCY9/UGT1A9/ARRB1/GNAS/HRAS/KPNA2/UGT1A1/PRKCG/AKT2/KPNA7/UGT2A1/ADCY7/AHR/FGF17	14
KEGG	hsa05410	Hypertrophic cardiomyopathy	7/390	90/8135	0.1398	0.8203	0.8203	ITGA4/ITGB5/EMD/ACE/SLC8A3/ACTC1/PRKAB1	7
KEGG	hsa05332	Graft-versus-host disease	4/390	42/8135	0.1403	0.8203	0.8203	HLA-DPA1/KLRD1/FAS/PRF1	4
KEGG	hsa04714	Thermogenesis	15/390	232/8135	0.1465	0.8203	0.8203	NDUFA13/ADCY9/NDUFV2/PRDM16/NDUFB11/NDUFB3/GNAS/HRAS/PRKAB1/MGLL/SMARCE1/NDUFB7/ADCY7/NDUFA4/ATP5PD	15
KEGG	hsa00860	Porphyrin metabolism	4/390	43/8135	0.1493	0.8203	0.8203	UGT1A9/CPOX/UGT1A1/UGT2A1	4
KEGG	hsa04962	Vasopressin-regulated water reabsorption	4/390	44/8135	0.1584	0.8203	0.8203	VAMP2/ADCY9/DYNC1LI2/GNAS	4
KEGG	hsa04730	Long-term depression	5/390	60/8135	0.1592	0.8203	0.8203	GUCY1B1/GNAS/HRAS/PRKCG/GNAZ	5
KEGG	hsa04978	Mineral absorption	5/390	60/8135	0.1592	0.8203	0.8203	MT1H/MT1A/MT1B/CYBRD1/SLC8A3	5
KEGG	hsa00603	Glycosphingolipid biosynthesis - globo and isoglobo series	2/390	15/8135	0.1598	0.8203	0.8203	HEXA/NAGA	2
KEGG	hsa04744	Phototransduction	3/390	29/8135	0.1602	0.8203	0.8203	SLC24A1/RCVRN/GUCY2D	3
KEGG	hsa04810	Regulation of actin cytoskeleton	14/390	218/8135	0.1625	0.8203	0.8203	ITGA4/APC/NCKAP1L/ITGB5/BRK1/ROCK2/IQGAP2/DIAPH2/HRAS/CHRM2/MYL9/ARHGEF6/FGF17/PAK4	14
KEGG	hsa00140	Steroid hormone biosynthesis	5/390	61/8135	0.1671	0.8203	0.8203	UGT1A9/SRD5A2/SULT2B1/UGT1A1/UGT2A1	5
KEGG	hsa03022	Basal transcription factors	4/390	45/8135	0.1677	0.8203	0.8203	GTF2F1/GTF2IRD1/TAF5L/TAF10	4
KEGG	hsa04612	Antigen processing and presentation	6/390	78/8135	0.1701	0.8203	0.8203	CALR/KLRC4/HLA-DPA1/KLRD1/CANX/TAP1	6
KEGG	hsa00053	Ascorbate and aldarate metabolism	3/390	30/8135	0.172	0.8203	0.8203	UGT1A9/UGT1A1/UGT2A1	3
KEGG	hsa00630	Glyoxylate and dicarboxylate metabolism	3/390	30/8135	0.172	0.8203	0.8203	ACSS1/PCCB/HAO1	3
KEGG	hsa04213	Longevity regulating pathway - multiple species	5/390	62/8135	0.1751	0.8203	0.8203	ADCY9/HRAS/PRKAB1/AKT2/ADCY7	5
KEGG	hsa04022	cGMP-PKG signaling pathway	11/390	167/8135	0.1777	0.8203	0.8203	ADCY9/GUCY1B1/ROCK2/VDAC2/VDAC1/SLC8A3/AKT2/GTF2IRD1/MYL9/ADCY7/MEF2C	11
KEGG	hsa05166	Human T-cell leukemia virus 1 infection	14/390	222/8135	0.1788	0.8203	0.8203	ADCY9/CALR/HLA-DPA1/CDK4/HRAS/E2F2/CANX/VDAC2/VDAC1/AKT2/ADCY7/MMP7/KAT2B/NRP1	14
KEGG	hsa04713	Circadian entrainment	7/390	97/8135	0.183	0.8203	0.8203	ADCY9/GUCY1B1/GRIN2D/GNAS/PRKCG/ADCY7/GNG11	7
KEGG	hsa05215	Prostate cancer	7/390	97/8135	0.183	0.8203	0.8203	ETV5/TCF7/HRAS/E2F2/NKX3-1/SRD5A2/AKT2	7
KEGG	hsa05208	Chemical carcinogenesis - reactive oxygen species	14/390	223/8135	0.183	0.8203	0.8203	NDUFA13/NDUFV2/PRKD3/NDUFB11/NDUFB3/HRAS/VDAC2/VDAC1/AKT2/NDUFB7/ABL1/AHR/NDUFA4/ATP5PD	14
KEGG	hsa03250	Viral life cycle - HIV-1	5/390	63/8135	0.1833	0.8203	0.8203	APOBEC3G/APOBEC3D/NELFB/SAMHD1/KAT2B	5
KEGG	hsa01200	Carbon metabolism	8/390	115/8135	0.1862	0.8203	0.8203	ACSS1/IDH1/ALDOB/SUCLA2/PCCB/TPI1/HAO1/HK2	8
KEGG	hsa01522	Endocrine resistance	7/390	98/8135	0.1896	0.8203	0.8203	ADCY9/CDK4/GNAS/HRAS/E2F2/AKT2/ADCY7	7
KEGG	hsa00450	Selenocompound metabolism	2/390	17/8135	0.1948	0.8203	0.8203	KYAT1/SEPSECS	2
KEGG	hsa00640	Propanoate metabolism	3/390	32/8135	0.1965	0.8203	0.8203	ACSS1/SUCLA2/PCCB	3
KEGG	hsa01240	Biosynthesis of cofactors	10/390	153/8135	0.1986	0.8203	0.8203	GCH1/NME4/UGT1A9/MTHFD2L/CPOX/NADK2/UGT1A1/UGT2A1/GGCX/OXSM	10
KEGG	hsa04921	Oxytocin signaling pathway	10/390	154/8135	0.204	0.8203	0.8203	ADCY9/GUCY1B1/ROCK2/GNAS/HRAS/PRKAB1/PRKCG/MYL9/ADCY7/MEF2C	10
KEGG	hsa00051	Fructose and mannose metabolism	3/390	33/8135	0.209	0.8203	0.8203	ALDOB/TPI1/HK2	3
KEGG	hsa04932	Non-alcoholic fatty liver disease	10/390	155/8135	0.2095	0.8203	0.8203	NDUFA13/NDUFV2/NDUFB11/NDUFB3/PRKAB1/AKT2/NDUFB7/NDUFA4/CASP8/FAS	10
KEGG	hsa04934	Cushing syndrome	10/390	155/8135	0.2095	0.8203	0.8203	ADCY9/APC/TCF7/FZD8/CDK4/GNAS/E2F2/ADCY7/AHR/LDLR	10
KEGG	hsa04916	Melanogenesis	7/390	101/8135	0.2099	0.8203	0.8203	ADCY9/TCF7/FZD8/GNAS/HRAS/PRKCG/ADCY7	7
KEGG	hsa04071	Sphingolipid signaling pathway	8/390	119/8135	0.211	0.8203	0.8203	ACER2/ROCK2/S1PR5/HRAS/PRKCG/AKT2/PPP2R5D/ASAH1	8
KEGG	hsa00511	Other glycan degradation	2/390	18/8135	0.2126	0.8203	0.8203	HEXA/NEU1	2
KEGG	hsa04979	Cholesterol metabolism	4/390	50/8135	0.2171	0.8203	0.8203	NPC1/VDAC2/VDAC1/LDLR	4
KEGG	hsa00830	Retinol metabolism	5/390	68/8135	0.2262	0.8203	0.8203	UGT1A9/UGT1A1/CYP2C18/UGT2A1/CYP27C1	5
KEGG	hsa04913	Ovarian steroidogenesis	4/390	51/8135	0.2274	0.8203	0.8203	ADCY9/GNAS/ADCY7/LDLR	4
KEGG	hsa04742	Taste transduction	6/390	86/8135	0.23	0.8203	0.8203	TAS2R60/GABBR1/ASIC2/TAS2R3/TAS2R9/PKD1L3	6
KEGG	hsa05210	Colorectal cancer	6/390	86/8135	0.23	0.8203	0.8203	APC/TCF7/MLH1/HRAS/DCC/AKT2	6
KEGG	hsa05204	Chemical carcinogenesis - DNA adducts	5/390	69/8135	0.2351	0.8203	0.8203	UGT1A9/UGT1A1/HPGDS/CYP2C18/UGT2A1	5
KEGG	hsa05020	Prion disease	16/390	273/8135	0.2369	0.8203	0.8203	NDUFA13/NDUFV2/CSNK2A3/PSMD9/STIP1/GRIN2D/PSMB2/NDUFB11/NDUFB3/TUBA8/VDAC2/VDAC1/CSNK2A1/NDUFB7/NDUFA4/ATP5PD	16
KEGG	hsa00600	Sphingolipid metabolism	4/390	52/8135	0.2378	0.8203	0.8203	ACER2/HEXA/NEU1/ASAH1	4
KEGG	hsa04512	ECM-receptor interaction	6/390	88/8135	0.246	0.8203	0.8203	GP9/ITGA4/LAMC2/ITGB5/GP1BA/COMP	6
KEGG	hsa04550	Signaling pathways regulating pluripotency of stem cells	9/390	143/8135	0.2473	0.8203	0.8203	APC/PCGF5/TCF7/FZD8/HRAS/SMAD5/LIFR/PAX6/AKT2	9
KEGG	hsa00500	Starch and sucrose metabolism	3/390	36/8135	0.2476	0.8203	0.8203	GANC/ENPP3/HK2	3
KEGG	hsa00512	Mucin type O-glycan biosynthesis	3/390	36/8135	0.2476	0.8203	0.8203	GALNT2/GALNT14/GALNT8	3
KEGG	hsa04961	Endocrine and other factor-regulated calcium reabsorption	4/390	53/8135	0.2483	0.8203	0.8203	ADCY9/GNAS/SLC8A3/PRKCG	4
KEGG	hsa05320	Autoimmune thyroid disease	4/390	53/8135	0.2483	0.8203	0.8203	HLA-DPA1/IFNA1/FAS/PRF1	4
KEGG	hsa04520	Adherens junction	5/390	71/8135	0.2532	0.8203	0.8203	CSNK2A3/TCF7/CSNK2A1/NECTIN3/CDH1	5
KEGG	hsa04727	GABAergic synapse	6/390	89/8135	0.254	0.8203	0.8203	ADCY9/GABBR1/SLC38A5/PRKCG/ADCY7/GNG11	6
KEGG	hsa05216	Thyroid cancer	3/390	37/8135	0.2606	0.8203	0.8203	TCF7/HRAS/CDH1	3
KEGG	hsa00982	Drug metabolism - cytochrome P450	5/390	72/8135	0.2624	0.8203	0.8203	UGT1A9/UGT1A1/HPGDS/UGT2A1/FMO5	5
KEGG	hsa05223	Non-small cell lung cancer	5/390	72/8135	0.2624	0.8203	0.8203	CDK4/HRAS/E2F2/PRKCG/AKT2	5
KEGG	hsa05022	Pathways of neurodegeneration - multiple diseases	26/390	476/8135	0.2704	0.8203	0.8203	NDUFA13/ACTR1B/APC/NDUFV2/CSNK2A3/PSMD9/FIG4/GRIN2D/PSMB2/FZD8/NDUFB11/NDUFB3/HRAS/TUBA8/VDAC2/VDAC1/CSNK2A1/PRKCG/CAPN2/NDUFB7/LRP5/CSNK1A1/NDUFA4/CASP8/FAS/ATP5PD	26
KEGG	hsa00230	Purine metabolism	8/390	128/8135	0.2709	0.8203	0.8203	ADCY9/NME4/GUCY1B1/NT5M/ENTPD3/ADCY7/ENPP3/GUCY2D	8
KEGG	hsa05330	Allograft rejection	3/390	38/8135	0.2738	0.8203	0.8203	HLA-DPA1/FAS/PRF1	3
KEGG	hsa04926	Relaxin signaling pathway	8/390	129/8135	0.2779	0.8203	0.8203	ADCY9/ARRB1/GNAS/HRAS/VEGFB/AKT2/ADCY7/GNG11	8
KEGG	hsa00513	Various types of N-glycan biosynthesis	3/390	39/8135	0.2871	0.8203	0.8203	HEXA/DDOST/CHST9	3
KEGG	hsa04970	Salivary secretion	6/390	93/8135	0.2871	0.8203	0.8203	VAMP2/ADCY9/GUCY1B1/GNAS/PRKCG/ADCY7	6
KEGG	hsa04918	Thyroid hormone synthesis	5/390	75/8135	0.2903	0.8203	0.8203	ADCY9/GNAS/CANX/PRKCG/ADCY7	5
KEGG	hsa05214	Glioma	5/390	75/8135	0.2903	0.8203	0.8203	CDK4/HRAS/E2F2/PRKCG/AKT2	5
KEGG	hsa04650	Natural killer cell mediated cytotoxicity	8/390	131/8135	0.2919	0.8203	0.8203	CD244/IFNA1/HRAS/KLRD1/PRKCG/ULBP3/FAS/PRF1	8
KEGG	hsa04261	Adrenergic signaling in cardiomyocytes	9/390	150/8135	0.2923	0.8203	0.8203	ADCY9/GNAS/SLC8A3/ACTC1/AKT2/ADCY7/PPP1R1A/MYL4/PPP2R5D	9
KEGG	hsa05012	Parkinson disease	15/390	266/8135	0.2945	0.8203	0.8203	NDUFA13/NDUFV2/PSMD9/SLC39A7/PSMB2/SLC39A11/NDUFB11/NDUFB3/GNAS/TUBA8/VDAC2/VDAC1/NDUFB7/NDUFA4/ATP5PD	15
KEGG	hsa04725	Cholinergic synapse	7/390	113/8135	0.298	0.8203	0.8203	ADCY9/HRAS/PRKCG/CHRM2/AKT2/ADCY7/GNG11	7
KEGG	hsa04971	Gastric acid secretion	5/390	76/8135	0.2998	0.8203	0.8203	ADCY9/GNAS/PRKCG/KCNK10/ADCY7	5
KEGG	hsa05220	Chronic myeloid leukemia	5/390	76/8135	0.2998	0.8203	0.8203	CDK4/HRAS/E2F2/AKT2/ABL1	5
KEGG	hsa00240	Pyrimidine metabolism	4/390	58/8135	0.3023	0.8203	0.8203	NME4/NT5M/ENTPD3/ENPP3	4
KEGG	hsa04145	Phagosome	9/390	152/8135	0.3056	0.8203	0.8203	CALR/ITGB5/DYNC1LI2/HLA-DPA1/TUBA8/CANX/COMP/TAP1/ATP6AP1	9
KEGG	hsa04015	Rap1 signaling pathway	12/390	210/8135	0.3067	0.8203	0.8203	ADCY9/RAPGEF1/PRKD3/GNAS/HRAS/VEGFB/PRKCG/AKT2/ADCY7/PARD6A/CDH1/FGF17	12
KEGG	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	5/390	77/8135	0.3093	0.8203	0.8203	ITGA4/ITGB5/TCF7/EMD/SLC8A3	5
KEGG	hsa00190	Oxidative phosphorylation	8/390	134/8135	0.3133	0.8203	0.8203	NDUFA13/NDUFV2/NDUFB11/NDUFB3/NDUFB7/NDUFA4/ATP6AP1/ATP5PD	8
KEGG	hsa04270	Vascular smooth muscle contraction	8/390	134/8135	0.3133	0.8203	0.8203	ADCY9/GUCY1B1/ROCK2/GNAS/PLA2G12A/PRKCG/MYL9/ADCY7	8
KEGG	hsa04726	Serotonergic synapse	7/390	115/8135	0.3135	0.8203	0.8203	ALOX12/PTGS1/GNAS/HRAS/PRKCG/CYP2C18/GNG11	7
KEGG	hsa03015	mRNA surveillance pathway	6/390	97/8135	0.321	0.822	0.822	CASC3/GSPT2/CSTF2T/ACIN1/CPSF4L/PPP2R5D	6
KEGG	hsa05416	Viral myocarditis	4/390	60/8135	0.3242	0.822	0.822	HLA-DPA1/ABL1/CASP8/PRF1	4
KEGG	hsa01521	EGFR tyrosine kinase inhibitor resistance	5/390	79/8135	0.3284	0.822	0.822	HRAS/GAB1/PRKCG/ERBB3/AKT2	5
KEGG	hsa04750	Inflammatory mediator regulation of TRP channels	6/390	98/8135	0.3295	0.822	0.822	ADCY9/ALOX12/ASIC2/GNAS/PRKCG/ADCY7	6
KEGG	hsa04925	Aldosterone synthesis and secretion	6/390	98/8135	0.3295	0.822	0.822	ADCY9/PRKD3/GNAS/PRKCG/ADCY7/LDLR	6
KEGG	hsa04150	mTOR signaling pathway	9/390	156/8135	0.3325	0.822	0.822	FZD8/LAMTOR1/DEPDC5/HRAS/GRB10/PRKCG/PRR5L/AKT2/LRP5	9
KEGG	hsa00561	Glycerolipid metabolism	4/390	61/8135	0.3353	0.822	0.822	AGK/MGLL/AGPAT1/MBOAT2	4
KEGG	hsa00590	Arachidonic acid metabolism	4/390	61/8135	0.3353	0.822	0.822	ALOX12/PTGS1/PLA2G12A/HPGDS	4
KEGG	hsa05160	Hepatitis C	9/390	157/8135	0.3393	0.822	0.822	IFNA1/TRAF3/CDK4/HRAS/E2F2/AKT2/LDLR/CASP8/FAS	9
KEGG	hsa04940	Type I diabetes mellitus	3/390	43/8135	0.3403	0.822	0.822	HLA-DPA1/FAS/PRF1	3
KEGG	hsa04935	Growth hormone synthesis, secretion and action	7/390	119/8135	0.3448	0.8251	0.8251	ADCY9/GNAS/HRAS/IGFALS/PRKCG/AKT2/ADCY7	7
KEGG	hsa05162	Measles	8/390	139/8135	0.3496	0.8251	0.8251	CSNK2A3/IFNA1/TRAF3/CDK4/CSNK2A1/AKT2/CASP8/FAS	8
KEGG	hsa04950	Maturity onset diabetes of the young	2/390	26/8135	0.3564	0.8251	0.8251	PAX6/HES1	2
KEGG	hsa04146	Peroxisome	5/390	82/8135	0.3572	0.8251	0.8251	IDH1/AGPS/ACOX2/CRAT/HAO1	5
KEGG	hsa04623	Cytosolic DNA-sensing pathway	4/390	63/8135	0.3574	0.8251	0.8251	POLR3G/CGAS/IFNA1/IL18	4
KEGG	hsa05217	Basal cell carcinoma	4/390	63/8135	0.3574	0.8251	0.8251	APC/TCF7/GLI2/FZD8	4
KEGG	hsa05142	Chagas disease	6/390	102/8135	0.364	0.8313	0.8313	CALR/ACE/GNAS/AKT2/CASP8/FAS	6
KEGG	hsa04020	Calcium signaling pathway	13/390	240/8135	0.3653	0.8313	0.8313	ADCY9/TBXA2R/GRIN2D/GNAS/VDAC2/VDAC1/SLC8A3/VEGFB/PRKCG/ERBB3/CHRM2/ADCY7/FGF17	13
KEGG	hsa04974	Protein digestion and absorption	6/390	103/8135	0.3727	0.8326	0.8326	SLC36A4/PRSS1/SLC7A7/COL5A1/SLC8A3/KCNJ13	6
KEGG	hsa05161	Hepatitis B	9/390	162/8135	0.3736	0.8326	0.8326	IFNA1/TRAF3/HRAS/E2F2/PRKCG/AKT2/CASP8/FAS/ATP6AP1	9
KEGG	hsa01040	Biosynthesis of unsaturated fatty acids	2/390	27/8135	0.3739	0.8326	0.8326	ACOT7/HACD1	2
KEGG	hsa04927	Cortisol synthesis and secretion	4/390	65/8135	0.3794	0.839	0.839	ADCY9/GNAS/ADCY7/LDLR	4
KEGG	hsa05205	Proteoglycans in cancer	11/390	205/8135	0.3945	0.8575	0.8575	ITGB5/ROCK2/FZD8/HRAS/GAB1/PRKCG/ERBB3/AKT2/CD63/FAS/DDX5	11
KEGG	hsa04911	Insulin secretion	5/390	86/8135	0.3958	0.8575	0.8575	VAMP2/ADCY9/GNAS/PRKCG/ADCY7	5
KEGG	hsa00010	Glycolysis / Gluconeogenesis	4/390	67/8135	0.4014	0.8575	0.8575	ACSS1/ALDOB/TPI1/HK2	4
KEGG	hsa04720	Long-term potentiation	4/390	67/8135	0.4014	0.8575	0.8575	GRIN2D/HRAS/PRKCG/PPP1R1A	4
KEGG	hsa05221	Acute myeloid leukemia	4/390	67/8135	0.4014	0.8575	0.8575	TCF7/ZBTB16/HRAS/AKT2	4
KEGG	hsa04664	Fc epsilon RI signaling pathway	4/390	68/8135	0.4124	0.8661	0.8661	BTK/HRAS/AKT2/ALOX5AP	4
KEGG	hsa05132	Salmonella infection	13/390	249/8135	0.4165	0.8661	0.8661	ACTR1B/NCKAP1L/TCF7/DYNC1LI2/BRK1/ROCK2/HRAS/TUBA8/AKT2/AHNAK/MYL9/CASP8/IL18	13
KEGG	hsa00130	Ubiquinone and other terpenoid-quinone biosynthesis	1/390	11/8135	0.4177	0.8661	0.8661	GGCX	1
KEGG	hsa04211	Longevity regulating pathway	5/390	89/8135	0.4246	0.8661	0.8661	ADCY9/HRAS/PRKAB1/AKT2/ADCY7	5
KEGG	hsa00020	Citrate cycle (TCA cycle)	2/390	30/8135	0.4252	0.8661	0.8661	IDH1/SUCLA2	2
KEGG	hsa04144	Endocytosis	13/390	251/8135	0.4279	0.8661	0.8661	SNX32/EHD3/ARRB1/BIN1/RAB11FIP2/IST1/HRAS/ASAP2/ARAP2/GRK5/PARD6A/GRK3/LDLR	13
KEGG	hsa05110	Vibrio cholerae infection	3/390	50/8135	0.4323	0.8661	0.8661	ADCY9/GNAS/ATP6AP1	3
KEGG	hsa04622	RIG-I-like receptor signaling pathway	4/390	70/8135	0.4342	0.8661	0.8661	ISG15/IFNA1/TRAF3/CASP8	4
KEGG	hsa05230	Central carbon metabolism in cancer	4/390	70/8135	0.4342	0.8661	0.8661	IDH1/HRAS/AKT2/HK2	4
KEGG	hsa04014	Ras signaling pathway	12/390	232/8135	0.4358	0.8661	0.8661	FOXO4/HRAS/GAB1/PLA2G12A/VEGFB/PRKCG/AKT2/GNG11/ABL1/FGF17/PAK4/RASGRF2	12
KEGG	hsa05171	Coronavirus disease - COVID-19	12/390	232/8135	0.4358	0.8661	0.8661	ISG15/RPL41/CGAS/MAS1/IFNA1/ACE/TRAF3/RPL29/RPL12/PRKCG/RPL27A/NRP1	12
KEGG	hsa00052	Galactose metabolism	2/390	31/8135	0.4418	0.8671	0.8671	GANC/HK2	2
KEGG	hsa04710	Circadian rhythm	2/390	31/8135	0.4418	0.8671	0.8671	NR1D1/PRKAB1	2
KEGG	hsa04060	Cytokine-cytokine receptor interaction	15/390	295/8135	0.4452	0.8683	0.8683	PPBP/TNFSF12/IL10RA/XCL1/CX3CL1/PF4V1/IFNA1/IL12RB1/LIFR/PF4/MPL/XCR1/XCL2/FAS/IL18	15
KEGG	hsa05145	Toxoplasmosis	6/390	112/8135	0.4505	0.8683	0.8683	IL10RA/LAMC2/HLA-DPA1/AKT2/LDLR/CASP8	6
KEGG	hsa05222	Small cell lung cancer	5/390	92/8135	0.4532	0.8683	0.8683	LAMC2/TRAF3/CDK4/E2F2/AKT2	5
KEGG	hsa05167	Kaposi sarcoma-associated herpesvirus infection	10/390	194/8135	0.4535	0.8683	0.8683	TCF7/IFNA1/TRAF3/CDK4/HRAS/E2F2/AKT2/GNG11/CASP8/FAS	10
KEGG	hsa01524	Platinum drug resistance	4/390	73/8135	0.4664	0.8818	0.8818	MLH1/AKT2/CASP8/FAS	4
KEGG	hsa03450	Non-homologous end-joining	1/390	13/8135	0.4723	0.8818	0.8818	XRCC6	1
KEGG	hsa05130	Pathogenic Escherichia coli infection	10/390	197/8135	0.473	0.8818	0.8818	MYO1G/NCKAP1L/BRK1/ROCK2/BAIAP2L1/TUBA8/ABL1/CASP8/FAS/IL18	10
KEGG	hsa03410	Base excision repair	2/390	33/8135	0.4743	0.8818	0.8818	PARP2/PARP4	2
KEGG	hsa04218	Cellular senescence	8/390	156/8135	0.4746	0.8818	0.8818	CDK4/HRAS/E2F2/VDAC2/VDAC1/CAPN2/AKT2/RBBP4	8
KEGG	hsa04390	Hippo signaling pathway	8/390	157/8135	0.4819	0.8867	0.8867	APC/TCF7/GLI2/FZD8/LIMD1/AMOT/PARD6A/CDH1	8
KEGG	hsa03460	Fanconi anemia pathway	3/390	54/8135	0.4829	0.8867	0.8867	BRIP1/MLH1/HES1	3
KEGG	hsa03010	Ribosome	8/390	158/8135	0.4891	0.8869	0.8869	RPL41/MRPS18C/MRPS6/RPL29/MRPL10/RPL12/RPL27A/MRPL34	8
KEGG	hsa04915	Estrogen signaling pathway	7/390	138/8135	0.4948	0.8869	0.8869	ADCY9/GABBR1/GNAS/HRAS/FKBP5/AKT2/ADCY7	7
KEGG	hsa05212	Pancreatic cancer	4/390	76/8135	0.4979	0.8869	0.8869	CDK4/E2F2/AKT2/ARHGEF6	4
KEGG	hsa04070	Phosphatidylinositol signaling system	5/390	97/8135	0.4998	0.8869	0.8869	PI4KB/OCRL/INPP4A/PRKCG/IPPK	5
KEGG	hsa04666	Fc gamma R-mediated phagocytosis	5/390	97/8135	0.4998	0.8869	0.8869	MARCKS/BIN1/ASAP2/PRKCG/AKT2	5
KEGG	hsa05016	Huntington disease	15/390	306/8135	0.5032	0.8869	0.8869	NDUFA13/ACTR1B/NDUFV2/PSMD9/SLC1A3/PSMB2/NDUFB11/NDUFB3/TUBA8/VDAC2/VDAC1/NDUFB7/NDUFA4/CASP8/ATP5PD	15
KEGG	hsa04722	Neurotrophin signaling pathway	6/390	119/8135	0.5096	0.8869	0.8869	RAPGEF1/IRAK3/HRAS/GAB1/AKT2/ABL1	6
KEGG	hsa00980	Metabolism of xenobiotics by cytochrome P450	4/390	78/8135	0.5185	0.8869	0.8869	UGT1A9/UGT1A1/HPGDS/UGT2A1	4
KEGG	hsa01212	Fatty acid metabolism	3/390	57/8135	0.5193	0.8869	0.8869	PPT2/HACD1/OXSM	3
KEGG	hsa05134	Legionellosis	3/390	57/8135	0.5193	0.8869	0.8869	EEF1A2/CASP8/IL18	3
KEGG	hsa00350	Tyrosine metabolism	2/390	36/8135	0.5207	0.8869	0.8869	AOC3/GSTZ1	2
KEGG	hsa00604	Glycosphingolipid biosynthesis - ganglio series	1/390	15/8135	0.5217	0.8869	0.8869	HEXA	1
KEGG	hsa05206	MicroRNAs in cancer	15/390	310/8135	0.524	0.8869	0.8869	APC/ZEB2/MARCKS/VIM/MIR32/HRAS/MIR106B/MIR1-2/E2F2/MIR126/PRKCG/ERBB3/MIR27B/ABL1/PAK4	15
KEGG	hsa04621	NOD-like receptor signaling pathway	9/390	184/8135	0.5245	0.8869	0.8869	IFNA1/TRAF3/VDAC2/VDAC1/PANX1/TXNIP/CASP8/GBP4/IL18	9
KEGG	hsa04936	Alcoholic liver disease	7/390	142/8135	0.5253	0.8869	0.8869	TCF7/IFNA1/TRAF3/PRKAB1/AKT2/CASP8/FAS	7
KEGG	hsa00480	Glutathione metabolism	3/390	58/8135	0.5311	0.89	0.89	IDH1/OPLAH/HPGDS	3
KEGG	hsa05017	Spinocerebellar ataxia	7/390	143/8135	0.5329	0.89	0.89	PSMD9/GRIN2D/PSMB2/VDAC2/VDAC1/PRKCG/AKT2	7
KEGG	hsa00983	Drug metabolism - other enzymes	4/390	80/8135	0.5387	0.8908	0.8908	NME4/UGT1A9/UGT1A1/UGT2A1	4
KEGG	hsa04370	VEGF signaling pathway	3/390	59/8135	0.5428	0.8908	0.8908	HRAS/PRKCG/AKT2	3
KEGG	hsa00360	Phenylalanine metabolism	1/390	16/8135	0.5447	0.8908	0.8908	AOC3	1
KEGG	hsa00430	Taurine and hypotaurine metabolism	1/390	16/8135	0.5447	0.8908	0.8908	FMO5	1
KEGG	hsa05340	Primary immunodeficiency	2/390	38/8135	0.5501	0.895	0.895	BTK/TAP1	2
KEGG	hsa04660	T cell receptor signaling pathway	5/390	104/8135	0.5624	0.9056	0.9056	TEC/CDK4/HRAS/AKT2/PAK4	5
KEGG	hsa03040	Spliceosome	7/390	147/8135	0.5625	0.9056	0.9056	DDX23/DHX38/SF3A3/ACIN1/SNRNP70/HNRNPA1/DDX5	7
KEGG	hsa00120	Primary bile acid biosynthesis	1/390	17/8135	0.5666	0.9056	0.9056	ACOX2	1
KEGG	hsa04072	Phospholipase D signaling pathway	7/390	148/8135	0.5698	0.9056	0.9056	ADCY9/GNAS/HRAS/GAB1/AKT2/ADCY7/AGPAT1	7
KEGG	hsa04514	Cell adhesion molecules	7/390	149/8135	0.577	0.9056	0.9056	NEO1/ITGA4/HLA-DPA1/VCAN/NRXN1/NECTIN3/CDH1	7
KEGG	hsa05014	Amyotrophic lateral sclerosis	17/390	364/8135	0.5814	0.9056	0.9056	NDUFA13/ACTR1B/NDUFV2/PSMD9/FIG4/GRIN2D/PSMB2/NDUFB11/NDUFB3/HNRNPA2B1/POM121/TUBA8/VDAC1/NDUFB7/HNRNPA1/NDUFA4/ATP5PD	17
KEGG	hsa01232	Nucleotide metabolism	4/390	85/8135	0.5872	0.9056	0.9056	NME4/NT5M/ENTPD3/ENPP3	4
KEGG	hsa00061	Fatty acid biosynthesis	1/390	18/8135	0.5874	0.9056	0.9056	OXSM	1
KEGG	hsa04066	HIF-1 signaling pathway	5/390	109/8135	0.6046	0.9056	0.9056	ELOB/ALDOB/PRKCG/AKT2/HK2	5
KEGG	hsa04114	Oocyte meiosis	6/390	131/8135	0.6046	0.9056	0.9056	ADCY9/SMC1B/SLK/SPDYE1/ADCY7/PPP2R5D	6
KEGG	hsa00380	Tryptophan metabolism	2/390	42/8135	0.605	0.9056	0.9056	ASMT/KYAT1	2
KEGG	hsa04260	Cardiac muscle contraction	4/390	87/8135	0.6057	0.9056	0.9056	SLC9A7/SLC8A3/ACTC1/MYL4	4
KEGG	hsa00531	Glycosaminoglycan degradation	1/390	19/8135	0.6072	0.9056	0.9056	HEXA	1
KEGG	hsa01210	2-Oxocarboxylic acid metabolism	1/390	19/8135	0.6072	0.9056	0.9056	IDH1	1
KEGG	hsa05321	Inflammatory bowel disease	3/390	65/8135	0.6092	0.9056	0.9056	HLA-DPA1/IL12RB1/IL18	3
KEGG	hsa04728	Dopaminergic synapse	6/390	132/8135	0.6121	0.9056	0.9056	ARRB1/GNAS/PRKCG/AKT2/GNG11/PPP2R5D	6
KEGG	hsa04975	Fat digestion and absorption	2/390	43/8135	0.6179	0.9056	0.9056	PLA2G12A/AGPAT1	2
KEGG	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	4/390	89/8135	0.6237	0.9056	0.9056	CSNK2A3/HRAS/CSNK2A1/AKT2	4
KEGG	hsa00670	One carbon pool by folate	1/390	20/8135	0.6261	0.9056	0.9056	MTHFD2L	1
KEGG	hsa04668	TNF signaling pathway	5/390	112/8135	0.6287	0.9056	0.9056	CX3CL1/TRAF3/AKT2/CASP8/FAS	5
KEGG	hsa02010	ABC transporters	2/390	45/8135	0.6428	0.9056	0.9056	ABCB4/TAP1	2
KEGG	hsa05131	Shigellosis	11/390	247/8135	0.6439	0.9056	0.9056	CGAS/UBE2NL/ROCK2/FOXO4/H3C6/VDAC1/CAPN2/AKT2/MYL9/HK2/IL18	11
KEGG	hsa00770	Pantothenate and CoA biosynthesis	1/390	21/8135	0.6441	0.9056	0.9056	ENPP3	1
KEGG	hsa04217	Necroptosis	7/390	159/8135	0.6459	0.9056	0.9056	MACROH2A1/IFNA1/VDAC2/VDAC1/CAPN2/CASP8/FAS	7
KEGG	hsa04924	Renin secretion	3/390	69/8135	0.6497	0.9056	0.9056	GUCY1B1/ACE/GNAS	3
KEGG	hsa05031	Amphetamine addiction	3/390	69/8135	0.6497	0.9056	0.9056	GRIN2D/GNAS/PRKCG	3
KEGG	hsa03050	Proteasome	2/390	46/8135	0.6547	0.9056	0.9056	PSMD9/PSMB2	2
KEGG	hsa04912	GnRH signaling pathway	4/390	93/8135	0.6582	0.9056	0.9056	ADCY9/GNAS/HRAS/ADCY7	4
KEGG	hsa05323	Rheumatoid arthritis	4/390	93/8135	0.6582	0.9056	0.9056	ACP5/HLA-DPA1/ATP6AP1/IL18	4
KEGG	hsa00900	Terpenoid backbone biosynthesis	1/390	22/8135	0.6612	0.9056	0.9056	ZMPSTE24	1
KEGG	hsa04630	JAK-STAT signaling pathway	7/390	162/8135	0.6652	0.9056	0.9056	IL10RA/IFNA1/HRAS/IL12RB1/LIFR/MPL/AKT2	7
KEGG	hsa04973	Carbohydrate digestion and absorption	2/390	47/8135	0.6663	0.9056	0.9056	AKT2/HK2	2
KEGG	hsa04350	TGF-beta signaling pathway	4/390	94/8135	0.6665	0.9056	0.9056	NEO1/SMAD5/GREM1/LTBP1	4
KEGG	hsa04657	IL-17 signaling pathway	4/390	94/8135	0.6665	0.9056	0.9056	S100A7A/TRAF3/CASP8/ELAVL1	4
KEGG	hsa03430	Mismatch repair	1/390	23/8135	0.6775	0.9056	0.9056	MLH1	1
KEGG	hsa04137	Mitophagy - animal	3/390	72/8135	0.6781	0.9056	0.9056	CSNK2A3/HRAS/CSNK2A1	3
KEGG	hsa04115	p53 signaling pathway	3/390	73/8135	0.6871	0.9056	0.9056	CDK4/CASP8/FAS	3
KEGG	hsa04152	AMPK signaling pathway	5/390	120/8135	0.6886	0.9056	0.9056	RAB2A/PRKAB1/AKT2/ELAVL1/PPP2R5D	5
KEGG	hsa00520	Amino sugar and nucleotide sugar metabolism	2/390	49/8135	0.6886	0.9056	0.9056	HEXA/HK2	2
KEGG	hsa00565	Ether lipid metabolism	2/390	49/8135	0.6886	0.9056	0.9056	AGPS/PLA2G12A	2
KEGG	hsa04672	Intestinal immune network for IgA production	2/390	49/8135	0.6886	0.9056	0.9056	ITGA4/HLA-DPA1	2
KEGG	hsa05030	Cocaine addiction	2/390	49/8135	0.6886	0.9056	0.9056	GRIN2D/GNAS	2
KEGG	hsa04919	Thyroid hormone signaling pathway	5/390	121/8135	0.6956	0.9056	0.9056	HDAC3/HRAS/PRKCG/AKT2/KAT2B	5
KEGG	hsa04613	Neutrophil extracellular trap formation	8/390	190/8135	0.6975	0.9056	0.9056	HDAC3/MACROH2A1/H3C6/VDAC2/VDAC1/PRKCG/GP1BA/AKT2	8
KEGG	hsa00564	Glycerophospholipid metabolism	4/390	98/8135	0.6982	0.9056	0.9056	PHOSPHO1/PLA2G12A/AGPAT1/MBOAT2	4
KEGG	hsa05144	Malaria	2/390	50/8135	0.6993	0.9056	0.9056	COMP/IL18	2
KEGG	hsa01230	Biosynthesis of amino acids	3/390	75/8135	0.7047	0.9056	0.9056	IDH1/ALDOB/TPI1	3
KEGG	hsa04640	Hematopoietic cell lineage	4/390	99/8135	0.7058	0.9056	0.9056	GP9/ITGA4/HLA-DPA1/GP1BA	4
KEGG	hsa04530	Tight junction	7/390	169/8135	0.7077	0.9056	0.9056	ROCK2/CDK4/TUBA8/PRKAB1/MYL9/AMOT/PARD6A	7
KEGG	hsa00592	alpha-Linolenic acid metabolism	1/390	25/8135	0.7077	0.9056	0.9056	PLA2G12A	1
KEGG	hsa00270	Cysteine and methionine metabolism	2/390	51/8135	0.7097	0.9056	0.9056	AHCYL2/KYAT1	2
KEGG	hsa05417	Lipid and atherosclerosis	9/390	215/8135	0.7099	0.9056	0.9056	IFNA1/ROCK2/TRAF3/HRAS/AKT2/LDLR/CASP8/FAS/IL18	9
KEGG	hsa04933	AGE-RAGE signaling pathway in diabetic complications	4/390	100/8135	0.7132	0.9056	0.9056	CDK4/HRAS/VEGFB/AKT2	4
KEGG	hsa05202	Transcriptional misregulation in cancer	8/390	193/8135	0.7139	0.9056	0.9056	BMP2K/ETV5/TSPAN7/ZBTB16/PTCRA/H3C6/MEF2C/DDX5	8
KEGG	hsa05100	Bacterial invasion of epithelial cells	3/390	77/8135	0.7215	0.9056	0.9056	ARHGAP10/GAB1/CDH1	3
KEGG	hsa05140	Leishmaniasis	3/390	77/8135	0.7215	0.9056	0.9056	ITGA4/HLA-DPA1/EEF1A2	3
KEGG	hsa00790	Folate biosynthesis	1/390	26/8135	0.7218	0.9056	0.9056	GCH1	1
KEGG	hsa04914	Progesterone-mediated oocyte maturation	4/390	102/8135	0.7277	0.9056	0.9056	ADCY9/SPDYE1/AKT2/ADCY7	4
KEGG	hsa04110	Cell cycle	5/390	126/8135	0.729	0.9056	0.9056	SMC1B/CDK4/E2F2/MCM5/ABL1	5
KEGG	hsa04721	Synaptic vesicle cycle	3/390	78/8135	0.7296	0.9056	0.9056	VAMP2/CPLX1/SLC1A3	3
KEGG	hsa04024	cAMP signaling pathway	9/390	221/8135	0.7399	0.9061	0.9061	ADCY9/GABBR1/GRIN2D/ROCK2/GNAS/CHRM2/AKT2/MYL9/ADCY7	9
KEGG	hsa04380	Osteoclast differentiation	5/390	128/8135	0.7416	0.9061	0.9061	TEC/ACP5/BTK/OSCAR/AKT2	5
KEGG	hsa04064	NF-kappa B signaling pathway	4/390	104/8135	0.7416	0.9061	0.9061	CSNK2A3/BTK/TRAF3/CSNK2A1	4
KEGG	hsa04620	Toll-like receptor signaling pathway	4/390	104/8135	0.7416	0.9061	0.9061	IFNA1/TRAF3/AKT2/CASP8	4
KEGG	hsa05168	Herpes simplex virus 1 infection	21/390	495/8135	0.7538	0.9146	0.9146	ZNF275/ZFP69B/CALR/EIF2B3/CGAS/ZNF169/ZNF595/HLA-DPA1/IFNA1/TRAF3/ZNF680/EIF2B2/ZNF284/ZNF23/AKT2/ZNF226/ZNF234/CASP8/FAS/TAP1/RBAK	21
KEGG	hsa00591	Linoleic acid metabolism	1/390	29/8135	0.76	0.9146	0.9146	PLA2G12A	1
KEGG	hsa04392	Hippo signaling pathway - multiple species	1/390	29/8135	0.76	0.9146	0.9146	LIMD1	1
KEGG	hsa04662	B cell receptor signaling pathway	3/390	82/8135	0.7603	0.9146	0.9146	BTK/HRAS/AKT2	3
KEGG	hsa05152	Tuberculosis	7/390	180/8135	0.767	0.9177	0.9177	IL10RA/HLA-DPA1/IFNA1/AKT2/CASP8/ATP6AP1/IL18	7
KEGG	hsa00030	Pentose phosphate pathway	1/390	30/8135	0.7716	0.9177	0.9177	ALDOB	1
KEGG	hsa01523	Antifolate resistance	1/390	30/8135	0.7716	0.9177	0.9177	ALOX12	1
KEGG	hsa00410	beta-Alanine metabolism	1/390	31/8135	0.7826	0.9238	0.9238	AOC3	1
KEGG	hsa05310	Asthma	1/390	31/8135	0.7826	0.9238	0.9238	HLA-DPA1	1
KEGG	hsa04910	Insulin signaling pathway	5/390	137/8135	0.793	0.9291	0.9291	RAPGEF1/HRAS/PRKAB1/AKT2/HK2	5
KEGG	hsa04215	Apoptosis - multiple species	1/390	32/8135	0.793	0.9291	0.9291	CASP8	1
KEGG	hsa05034	Alcoholism	7/390	187/8135	0.7998	0.9307	0.9307	HDAC3/MACROH2A1/GRIN2D/GNAS/HRAS/H3C6/GNG11	7
KEGG	hsa04130	SNARE interactions in vesicular transport	1/390	33/8135	0.803	0.9307	0.9307	VAMP2	1
KEGG	hsa04670	Leukocyte transendothelial migration	4/390	114/8135	0.8032	0.9307	0.9307	ITGA4/ROCK2/PRKCG/MYL9	4
KEGG	hsa04151	PI3K-Akt signaling pathway	14/390	354/8135	0.8095	0.9311	0.9311	ITGA4/LAMC2/ITGB5/IFNA1/CDK4/HRAS/VEGFB/ERBB3/CHRM2/AKT2/GNG11/COMP/FGF17/PPP2R5D	14
KEGG	hsa00310	Lysine degradation	2/390	63/8135	0.8122	0.9311	0.9311	PRDM16/PLOD3	2
KEGG	hsa03020	RNA polymerase	1/390	34/8135	0.8125	0.9311	0.9311	POLR3G	1
KEGG	hsa03030	DNA replication	1/390	36/8135	0.8301	0.9468	0.9468	MCM5	1
KEGG	hsa00250	Alanine, aspartate and glutamate metabolism	1/390	37/8135	0.8383	0.9468	0.9468	NAT8L	1
KEGG	hsa01250	Biosynthesis of nucleotide sugars	1/390	37/8135	0.8383	0.9468	0.9468	HK2	1
KEGG	hsa04960	Aldosterone-regulated sodium reabsorption	1/390	37/8135	0.8383	0.9468	0.9468	PRKCG	1
KEGG	hsa04920	Adipocytokine signaling pathway	2/390	69/8135	0.8503	0.9483	0.9483	PRKAB1/AKT2	2
KEGG	hsa05231	Choline metabolism in cancer	3/390	98/8135	0.8557	0.9483	0.9483	HRAS/PRKCG/AKT2	3
KEGG	hsa04917	Prolactin signaling pathway	2/390	70/8135	0.8559	0.9483	0.9483	HRAS/AKT2	2
KEGG	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	2/390	70/8135	0.8559	0.9483	0.9483	PTPRZ1/ATP6AP1	2
KEGG	hsa00260	Glycine, serine and threonine metabolism	1/390	40/8135	0.8605	0.9483	0.9483	AOC3	1
KEGG	hsa05033	Nicotine addiction	1/390	40/8135	0.8605	0.9483	0.9483	GRIN2D	1
KEGG	hsa03440	Homologous recombination	1/390	41/8135	0.8673	0.9483	0.9483	BRIP1	1
KEGG	hsa04216	Ferroptosis	1/390	41/8135	0.8673	0.9483	0.9483	VDAC2	1
KEGG	hsa04080	Neuroactive ligand-receptor interaction	13/390	353/8135	0.8727	0.9483	0.9483	PRSS1/MAS1/TBXA2R/GABBR1/GRIN2D/HRH4/S1PR5/PTGDR/NPY2R/GRIK5/CHRM2/GLRA1/SCT	13
KEGG	hsa05146	Amoebiasis	3/390	102/8135	0.8737	0.9483	0.9483	LAMC2/GNAS/PRKCG	3
KEGG	hsa04068	FoxO signaling pathway	4/390	131/8135	0.8803	0.9483	0.9483	FOXO4/HRAS/PRKAB1/AKT2	4
KEGG	hsa04625	C-type lectin receptor signaling pathway	3/390	104/8135	0.8819	0.9483	0.9483	HRAS/AKT2/CASP8	3
KEGG	hsa04922	Glucagon signaling pathway	3/390	107/8135	0.8933	0.9483	0.9483	GNAS/PRKAB1/AKT2	3
KEGG	hsa04930	Type II diabetes mellitus	1/390	46/8135	0.8963	0.9483	0.9483	HK2	1
KEGG	hsa04659	Th17 cell differentiation	3/390	108/8135	0.8969	0.9483	0.9483	HLA-DPA1/IL12RB1/AHR	3
KEGG	hsa03018	RNA degradation	2/390	79/8135	0.8984	0.9483	0.9483	MPHOSPH6/TENT4A	2
KEGG	hsa03008	Ribosome biogenesis in eukaryotes	3/390	109/8135	0.9004	0.9483	0.9483	CSNK2A3/CSNK2A1/POP1	3
KEGG	hsa05135	Yersinia infection	4/390	137/8135	0.9004	0.9483	0.9483	ITGA4/ROCK2/AKT2/IL18	4
KEGG	hsa00620	Pyruvate metabolism	1/390	47/8135	0.9013	0.9483	0.9483	ACSS1	1
KEGG	hsa04740	Olfactory transduction	16/390	440/8135	0.9046	0.9483	0.9483	ARRB1/OR52I2/OR2AP1/OR6C6/OR2M5/OR8K1/OR6C3/SLC8A3/OR1A2/OR52I1/OR51A2/OR8H1/GRK3/OR10A3/GUCY2D/OR52E2	16
KEGG	hsa04010	MAPK signaling pathway	10/390	294/8135	0.9048	0.9483	0.9483	ARRB1/HRAS/VEGFB/PRKCG/ERBB3/AKT2/FAS/MEF2C/FGF17/RASGRF2	10
KEGG	hsa00280	Valine, leucine and isoleucine degradation	1/390	48/8135	0.9061	0.9483	0.9483	PCCB	1
KEGG	hsa04120	Ubiquitin mediated proteolysis	4/390	142/8135	0.9149	0.9513	0.9513	UBE2NL/ELOB/UBE2U/UBE2Z	4
KEGG	hsa00510	N-Glycan biosynthesis	1/390	50/8135	0.9149	0.9513	0.9513	DDOST	1
KEGG	hsa04141	Protein processing in endoplasmic reticulum	5/390	171/8135	0.9186	0.952	0.952	CALR/DDOST/CANX/CAPN2/PLAA	5
KEGG	hsa05203	Viral carcinogenesis	6/390	204/8135	0.9314	0.9621	0.9621	HDAC3/TRAF3/CDK4/HRAS/KAT2B/CASP8	6
KEGG	hsa04658	Th1 and Th2 cell differentiation	2/390	92/8135	0.9397	0.9674	0.9674	HLA-DPA1/IL12RB1	2
KEGG	hsa05150	Staphylococcus aureus infection	2/390	96/8135	0.9487	0.9735	0.9735	HLA-DPA1/CFH	2
KEGG	hsa00970	Aminoacyl-tRNA biosynthesis	1/390	66/8135	0.9615	0.9808	0.9808	SEPSECS	1
KEGG	hsa05322	Systemic lupus erythematosus	3/390	136/8135	0.9621	0.9808	0.9808	MACROH2A1/HLA-DPA1/H3C6	3
KEGG	hsa04931	Insulin resistance	2/390	108/8135	0.9688	0.9845	0.9845	PRKAB1/AKT2	2
KEGG	hsa03320	PPAR signaling pathway	1/390	75/8135	0.9753	0.9859	0.9859	ACOX2	1
KEGG	hsa05133	Pertussis	1/390	76/8135	0.9765	0.9859	0.9859	IRF8	1
KEGG	hsa04610	Complement and coagulation cascades	1/390	85/8135	0.985	0.9913	0.9913	CFH	1
KEGG	hsa05418	Fluid shear stress and atherosclerosis	2/390	139/8135	0.9917	0.9924	0.9924	AKT2/MEF2C	2
KEGG	hsa04140	Autophagy - animal	2/390	141/8135	0.9924	0.9924	0.9924	HRAS/AKT2	2