ONTOLOGY	ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	qvalue	geneID	Count
KEGG	hsa05020	Prion disease	38/537	273/8135	8.212e-06	0.002453	0.002064	IL1A/CCL5/IL6/IL1B/PSMA2/PRKACB/PSMA5/PSMD14/SLC25A5/UQCRB/NDUFV1/PSMA1/PSMC2/CYCS/VDAC3/FYN/NDUFV2/TNF/COX6C/C8B/NDUFA10/SDHA/NDUFA4/PSMD12/CSNK2A2/NDUFA6/NDUFB4/CYC1/PIK3CA/MAPK3/PSMB1/SOD1/NDUFS1/NDUFS4/PIK3R1/GRIN2D/PSMC5/PSMA3	38
KEGG	hsa05321	Inflammatory bowel disease	15/537	65/8135	1.538e-05	0.002453	0.002064	HLA-DRB4/STAT4/IL1A/NFKB1/IL6/IFNG/IL1B/RORA/IL12B/HLA-DQB1/TNF/HLA-DOB/TBX21/IL23A/MAF	15
KEGG	hsa04660	T cell receptor signaling pathway	19/537	104/8135	4.155e-05	0.002787	0.002345	CD247/NFKB1/SOS1/IFNG/MALT1/NCK1/PRKCQ/ICOS/CBLB/FYN/CD8A/TNF/ITK/RASGRP1/LCK/PIK3CA/MAPK3/CD3E/PIK3R1	19
KEGG	hsa05010	Alzheimer disease	46/537	384/8135	5.009e-05	0.002787	0.002345	IL1A/NAE1/NFKB1/IL6/ATG14/CASP7/IL1B/CHRM5/PSMA2/CAPN1/ATP2A2/PSMA5/PSMD14/SLC25A5/UQCRB/NDUFV1/PSMA1/PSMC2/CYCS/VDAC3/NDUFV2/TNF/COX6C/NDUFA10/SDHA/NDUFA4/PSMD12/CSNK2A2/NDUFA6/LRP1/NDUFB4/CYC1/XBP1/APH1B/PLCB3/PIK3CA/MAPK3/PSMB1/NDUFS1/NDUFS4/PIK3R1/SLC39A6/GRIN2D/PSMC5/FZD2/PSMA3	46
KEGG	hsa05017	Spinocerebellar ataxia	23/537	143/8135	5.561e-05	0.002787	0.002345	ATG14/RORA/PSMA2/ATP2A2/PSMA5/PSMD14/SLC25A5/PSMA1/PSMC2/CYCS/VDAC3/PSMD12/XBP1/PUM1/PLCB3/PIK3CA/KCNC3/PSMB1/TBP/PIK3R1/GRIN2D/PSMC5/PSMA3	23
KEGG	hsa04672	Intestinal immune network for IgA production	12/537	49/8135	5.852e-05	0.002787	0.002345	HLA-DRB4/IL6/MADCAM1/ITGA4/TNFSF13/ICOS/HLA-DQB1/HLA-DOB/CXCR4/IL15RA/IL15/CCL25	12
KEGG	hsa05332	Graft-versus-host disease	11/537	42/8135	6.115e-05	0.002787	0.002345	HLA-DRB4/IL1A/IL6/IFNG/KLRD1/IL1B/HLA-DQB1/PRF1/GZMB/TNF/HLA-DOB	11
KEGG	hsa04940	Type I diabetes mellitus	11/537	43/8135	7.735e-05	0.003084	0.002595	HLA-DRB4/IL1A/IFNG/IL1B/IL12B/HLA-DQB1/PRF1/GZMB/TNF/HLA-DOB/GAD2	11
KEGG	hsa00020	Citrate cycle (TCA cycle)	9/537	30/8135	9.085e-05	0.00322	0.00271	MDH1/SUCLA2/DLD/CS/SDHA/SUCLG2/SUCLG1/FH/PDHB	9
KEGG	hsa05012	Parkinson disease	34/537	266/8135	0.0001411	0.004341	0.003653	PSMA2/GNAS/PRKACB/PSMA5/PSMD14/SLC25A5/UQCRB/NDUFV1/PSMA1/PSMC2/CYCS/VDAC3/NDUFV2/COX6C/NDUFA10/SDHA/NDUFA4/MFN1/PSMD12/NDUFA6/NDUFB4/CYC1/XBP1/UBA52/PSMB1/DAXX/UBB/SOD1/NDUFS1/NDUFS4/SLC39A6/UBE2J1/PSMC5/PSMA3	34
KEGG	hsa03050	Proteasome	11/537	46/8135	0.0001497	0.004341	0.003653	IFNG/PSMA2/PSMA5/PSMD14/PSMA1/PSMC2/PSME4/PSMD12/PSMB1/PSMC5/PSMA3	11
KEGG	hsa05022	Pathways of neurodegeneration - multiple diseases	52/537	476/8135	0.0001854	0.004929	0.004147	OPTN/IL1A/NFKB1/IL6/ATG14/CASP7/IL1B/CHRM5/PSMA2/CAT/CAPN1/ATP2A2/PSMA5/DERL1/PSMD14/SLC25A5/UQCRB/NDUFV1/PSMA1/PSMC2/CYCS/VDAC3/NDUFV2/TNF/COX6C/NDUFA10/SDHA/NDUFA4/MFN1/PSMD12/CSNK2A2/NDUFA6/NDUFB4/CYC1/XBP1/PLCB3/MAPK3/UBA52/PSMB1/PRPH/GPX7/DAXX/UBB/SOD1/DCTN6/NDUFS1/NDUFS4/GRIN2D/UBE2J1/PSMC5/FZD2/PSMA3	52
KEGG	hsa04659	Th17 cell differentiation	18/537	108/8135	0.0002234	0.005482	0.004613	CD247/HLA-DRB4/NFKB1/IL6/IFNG/TGFBR2/IL2RB/IL1B/RORA/PRKCQ/HLA-DQB1/HLA-DOB/TBX21/LCK/IL23A/RARA/MAPK3/CD3E	18
KEGG	hsa05014	Amyotrophic lateral sclerosis	42/537	364/8135	0.000246	0.005557	0.004676	OPTN/NUP107/ATG14/NUP37/PSMA2/CAT/PSMA5/DERL1/PSMD14/UQCRB/NDUFV1/PSMA1/PSMC2/CYCS/NDUFV2/TNF/COX6C/NDUFA10/SDHA/NUP205/NDUFA4/PSMD12/NDUFA6/NDUFB4/CYC1/XBP1/NUP85/HNRNPA2B1/PSMB1/PRPH/GPX7/DAXX/SETX/SOD1/DCTN6/NDUFS1/NUP160/NDUFS4/GRIN2D/PSMC5/NUP214/PSMA3	42
KEGG	hsa03010	Ribosome	23/537	158/8135	0.0002613	0.005557	0.004676	RPL6/RPS7/RPS5/MRPL9/RPL35/RPS4Y1/MRPS17/RPL35A/UBA52/RPL19/RSL24D1/MRPL22/RPL29/RPL15/RPS21/RPL11/MRPL19/RPL22/MRPS14/MRPL28/RPL36AL/RPL36/MRPL16	23
KEGG	hsa04932	Non-alcoholic fatty liver disease	22/537	155/8135	0.0005057	0.01008	0.008485	IL1A/NFKB1/IL6/CASP7/IL1B/UQCRB/NDUFV1/CYCS/NDUFV2/TNF/COX6C/NDUFA10/SDHA/NDUFA4/NDUFA6/NDUFB4/CYC1/XBP1/PIK3CA/NDUFS1/NDUFS4/PIK3R1	22
KEGG	hsa03040	Spliceosome	21/537	147/8135	0.0006175	0.01159	0.00975	DHX15/TRA2B/SRSF8/DDX46/SRSF10/EIF4A3/WBP11/SNRPD1/PCBP1/U2SURP/LSM8/PRPF8/SNRPF/PRPF38B/CDC40/SNRPD2/BCAS2/PQBP1/RBM25/LSM2/RBM8A	21
KEGG	hsa04640	Hematopoietic cell lineage	16/537	99/8135	0.0006998	0.0124	0.01043	CD38/HLA-DRB4/IL1A/IL6/CD2/IL1B/ITGA4/ITGA6/HLA-DQB1/CD8A/TNF/HLA-DOB/CD1A/CD9/CD3E/IL3	16
KEGG	hsa05415	Diabetic cardiomyopathy	26/537	203/8135	0.0008179	0.01355	0.0114	PARP1/NFKB1/TGFBR2/CTSD/ATP2A2/SLC25A5/UQCRB/NDUFV1/VDAC3/NDUFV2/PPP1CC/COX6C/NDUFA10/SDHA/NDUFA4/NDUFA6/NDUFB4/CYC1/TBC1D4/PLCB3/PIK3CA/PDHB/NDUFS1/NDUFS4/PIK3R1/GFPT1	26
KEGG	hsa00640	Propanoate metabolism	8/537	32/8135	0.0008744	0.01355	0.0114	ABAT/LDHB/SUCLA2/DLD/SUCLG2/BCKDHA/SUCLG1/ACSS3	8
KEGG	hsa04658	Th1 and Th2 cell differentiation	15/537	92/8135	0.0009275	0.01355	0.0114	CD247/HLA-DRB4/STAT4/NFKB1/IFNG/IL2RB/PRKCQ/IL12B/HLA-DQB1/HLA-DOB/TBX21/LCK/MAPK3/CD3E/MAF	15
KEGG	hsa05142	Chagas disease	16/537	102/8135	0.0009769	0.01355	0.0114	CD247/NFKB1/CCL5/IL6/IFNG/TGFBR2/IL1B/GNAS/IL12B/TNF/PLCB3/PIK3CA/MAPK3/TLR6/CD3E/PIK3R1	16
KEGG	hsa05146	Amoebiasis	16/537	102/8135	0.0009769	0.01355	0.0114	NFKB1/IL6/IFNG/IL1B/GNAS/PRKACB/IL12B/TNF/C8B/MUC2/CD1A/ACTN1/PLCB3/PIK3CA/CTSG/PIK3R1	16
KEGG	hsa05166	Human T-cell leukemia virus 1 infection	27/537	222/8135	0.001441	0.01915	0.01611	HLA-DRB4/MYC/NFKB1/IL6/TGFBR2/IL2RB/CDC23/CRTC3/PRKACB/ANAPC5/HLA-DQB1/SLC25A5/ZFP36/VDAC3/TNF/HLA-DOB/ATR/LCK/NFYB/IL15RA/PIK3CA/MAPK3/TBP/SPI1/IL15/CD3E/PIK3R1	27
KEGG	hsa05330	Allograft rejection	8/537	38/8135	0.002864	0.03655	0.03076	HLA-DRB4/IFNG/IL12B/HLA-DQB1/PRF1/GZMB/TNF/HLA-DOB	8
KEGG	hsa05164	Influenza A	21/537	171/8135	0.00418	0.05128	0.04315	HLA-DRB4/IL1A/NFKB1/CCL5/IL6/IFNG/IL1B/IL12B/HLA-DQB1/SLC25A5/CYCS/TNF/HLA-DOB/DNAJB1/TLR3/PIK3CA/RSAD2/MAPK3/TPSAB1/TPSB2/PIK3R1	21
KEGG	hsa05171	Coronavirus disease - COVID-19	26/537	232/8135	0.005395	0.06374	0.05363	NFKB1/IL6/IL1B/IL12B/RPL6/TNF/C8B/RPS7/RPS5/RPL35/RPS4Y1/TLR3/RPL35A/PIK3CA/MAPK3/UBA52/RPL19/RSL24D1/RPL29/RPL15/RPS21/RPL11/RPL22/RPL36AL/PIK3R1/RPL36	26
KEGG	hsa05016	Huntington disease	32/537	306/8135	0.006199	0.07062	0.05943	ATG14/PSMA2/PSMA5/PSMD14/SLC25A5/UQCRB/NDUFV1/PSMA1/PSMC2/CYCS/VDAC3/NDUFV2/COX6C/NDUFA10/SDHA/NDUFA4/PSMD12/NDUFA6/NDUFB4/CYC1/PLCB3/PSMB1/TBP/GPX7/SOD1/AP2B1/DCTN6/NDUFS1/NDUFS4/PSMC5/SLC1A3/PSMA3	32
KEGG	hsa04210	Apoptosis	17/537	136/8135	0.007946	0.07981	0.06716	PARP1/NFKB1/CASP7/CTSC/CAPN1/CTSD/PRF1/GZMB/CYCS/BIRC3/TNF/PIK3CA/MAPK3/DAXX/PMAIP1/PIK3R1/IL3	17
KEGG	hsa04620	Toll-like receptor signaling pathway	14/537	104/8135	0.008137	0.07981	0.06716	CXCL11/NFKB1/CCL5/IL6/IL1B/IL12B/TOLLIP/TNF/TLR3/PIK3CA/MAPK3/TLR6/PIK3R1/LBP	14
KEGG	hsa04625	C-type lectin receptor signaling pathway	14/537	104/8135	0.008137	0.07981	0.06716	NFKB1/IL6/IL1B/MALT1/RRAS/IL12B/CBLB/TNF/CLEC1B/IL23A/PIK3CA/MAPK3/RRAS2/PIK3R1	14
KEGG	hsa04020	Calcium signaling pathway	26/537	240/8135	0.008342	0.07981	0.06716	CD38/P2RX5/CHRM5/GNAS/PRKACB/ATP2A2/SLC25A5/P2RX1/VDAC3/ORAI3/NTSR1/ERBB3/CXCR4/PHKG1/HRH2/SLC8A2/PLCB3/CCKBR/SPHK2/AVPR1B/CHRM2/ATP2B2/P2RX6/MCOLN1/FGF18/GRIN2D	26
KEGG	hsa01200	Carbon metabolism	15/537	115/8135	0.008381	0.07981	0.06716	MDH1/PGK1/PRPS2/SUCLA2/DLD/CAT/CS/PRPS1/SDHA/SUCLG2/SUCLG1/FH/PFKP/PDHB/ACAT1	15
KEGG	hsa04110	Cell cycle	16/537	126/8135	0.008507	0.07981	0.06716	PCNA/MYC/SKP1/CDC23/CDC25B/ORC3/ANAPC5/RBX1/ORC2/YWHAQ/ATR/PKMYT1/CUL1/ORC4/CDC7/MCM6	16
KEGG	hsa05140	Leishmaniasis	11/537	77/8135	0.01175	0.1024	0.08618	HLA-DRB4/IL1A/NFKB1/IFNG/IL1B/ITGA4/IL12B/HLA-DQB1/TNF/HLA-DOB/MAPK3	11
KEGG	hsa05221	Acute myeloid leukemia	10/537	67/8135	0.01186	0.1024	0.08618	MYC/NFKB1/SOS1/RARA/PIK3CA/MAPK3/ZBTB16/SPI1/PIK3R1/IL3	10
KEGG	hsa05208	Chemical carcinogenesis - reactive oxygen species	24/537	223/8135	0.01188	0.1024	0.08618	NFKB1/SOS1/CAT/SLC25A5/UQCRB/NDUFV1/VDAC3/NDUFV2/COX6C/NDUFA10/SDHA/NDUFA4/NDUFA6/NDUFB4/CYC1/PIK3CA/MAPK3/GSTT2/AKR1C3/SOD1/NDUFS1/NDUFS4/GSTA3/PIK3R1	24
KEGG	hsa01523	Antifolate resistance	6/537	30/8135	0.01225	0.1028	0.08654	FOLR3/NFKB1/IL6/IL1B/TNF/ABCC4	6
KEGG	hsa00480	Glutathione metabolism	9/537	58/8135	0.013	0.1063	0.08948	OPLAH/LAP3/ODC1/GCLC/LANCL1/GSTT2/GPX7/PRDX6/GSTA3	9
KEGG	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	12/537	89/8135	0.01357	0.1082	0.09105	CD247/NFKB1/IFNG/PRKCQ/CSNK2A2/EML4/RASGRP1/LCK/PIK3CA/MAPK3/CD3E/PIK3R1	12
KEGG	hsa05310	Asthma	6/537	31/8135	0.01437	0.1118	0.09406	HLA-DRB4/HLA-DQB1/TNF/HLA-DOB/CCL11/IL3	6
KEGG	hsa05152	Tuberculosis	20/537	180/8135	0.01493	0.1127	0.09485	HLA-DRB4/IL1A/NFKB1/IL6/IFNG/IL1B/MALT1/CTSD/HSPA9/IL12B/HLA-DQB1/CYCS/TNF/HLA-DOB/NFYB/IL23A/MAPK3/SPHK2/TLR6/LBP	20
KEGG	hsa04668	TNF signaling pathway	14/537	112/8135	0.01519	0.1127	0.09485	NFKB1/CCL5/IL6/CASP7/IL1B/BIRC3/TNF/TRAF5/DNM1L/PIK3CA/MAPK3/LIF/IL15/PIK3R1	14
KEGG	hsa05323	Rheumatoid arthritis	12/537	93/8135	0.01877	0.134	0.1128	HLA-DRB4/IL1A/CCL5/IL6/IFNG/IL1B/TNFSF13/HLA-DQB1/TNF/HLA-DOB/IL23A/IL15	12
KEGG	hsa04064	NF-kappa B signaling pathway	13/537	104/8135	0.01891	0.134	0.1128	PARP1/NFKB1/IL1B/MALT1/PRKCQ/BIRC3/TNF/TRAF5/CSNK2A2/LCK/PIAS4/LBP/EDA2R	13
KEGG	hsa04657	IL-17 signaling pathway	12/537	94/8135	0.02028	0.1407	0.1184	NFKB1/IL6/IFNG/IL1B/USP25/ANAPC5/TNF/TRAF5/ELAVL1/MAPK3/CCL11/IL17B	12
KEGG	hsa04120	Ubiquitin mediated proteolysis	16/537	142/8135	0.02458	0.1657	0.1394	RCHY1/SKP1/CDC23/UBE2Q1/ANAPC5/CBLB/TRIM37/HERC1/BIRC3/RBX1/PIAS4/UBA52/CUL1/UBB/HERC2/UBE2J1	16
KEGG	hsa03015	mRNA surveillance pathway	12/537	97/8135	0.02535	0.1657	0.1394	PPP2R5C/GSPT2/EIF4A3/PPP1CC/PCF11/NUDT21/UPF3A/CSTF2T/PABPC1/GSPT1/RBM8A/UPF3B	12
KEGG	hsa04650	Natural killer cell mediated cytotoxicity	15/537	131/8135	0.02545	0.1657	0.1394	CD247/SOS1/SH2D1A/IFNG/KLRD1/PRF1/GZMB/CD244/FYN/TNF/LCK/CD48/PIK3CA/MAPK3/PIK3R1	15
KEGG	hsa00190	Oxidative phosphorylation	15/537	134/8135	0.03044	0.1942	0.1634	PPA1/UQCRB/NDUFV1/CYCS/NDUFV2/COX11/COX6C/NDUFA10/SDHA/NDUFA4/NDUFA6/NDUFB4/CYC1/NDUFS1/NDUFS4	15
KEGG	hsa04060	Cytokine-cytokine receptor interaction	28/537	295/8135	0.03242	0.1955	0.1645	CXCL11/IL1A/CCL5/IL6/IFNG/CCR3/TGFBR2/IL2RB/IL1B/TNFSF13/IL12B/CXCR6/ACVR1/TNF/CXCR4/IL36A/BMPR1B/IL15RA/IL23A/LIF/CCL11/AMHR2/IL15/CCL25/CCL23/IL17B/IL3/EDA2R	28
KEGG	hsa04960	Aldosterone-regulated sodium reabsorption	6/537	37/8135	0.03253	0.1955	0.1645	NR3C2/HSD11B2/PIK3CA/MAPK3/ATP1B1/PIK3R1	6
KEGG	hsa05143	African trypanosomiasis	6/537	37/8135	0.03253	0.1955	0.1645	IL6/IFNG/IL1B/IL12B/TNF/PLCB3	6
KEGG	hsa00620	Pyruvate metabolism	7/537	47/8135	0.0331	0.1955	0.1645	MDH1/LDHB/DLD/GLO1/FH/PDHB/ACAT1	7
KEGG	hsa03018	RNA degradation	10/537	79/8135	0.03418	0.1982	0.1668	BTG3/HSPA9/DCP1A/BTG2/EXOSC8/TTC37/PABPC1/LSM8/PFKP/LSM2	10
KEGG	hsa05135	Yersinia infection	15/537	137/8135	0.03612	0.205	0.1725	NFKB1/IL6/IL1B/ITGA4/CD8A/TNF/WAS/ARHGEF7/LCK/PIK3CA/MAPK3/ELMO2/ARHGEF28/RPS6KA3/PIK3R1	15
KEGG	hsa00280	Valine, leucine and isoleucine degradation	7/537	48/8135	0.03664	0.205	0.1725	ABAT/OXCT1/DLD/ACADM/BCKDHA/MCCC1/ACAT1	7
KEGG	hsa05132	Salmonella infection	24/537	249/8135	0.03892	0.2141	0.1801	RHOH/MYC/NFKB1/IL6/CASP7/IL1B/SKP1/RRAS/DYNLL1/CYCS/BIRC3/TNF/STX10/CYFIP2/EXOC7/RAB9A/PIK3CA/MAPK3/FYCO1/ELMO2/PIK3C2A/CSE1L/TLR6/DCTN6	24
KEGG	hsa05162	Measles	15/537	139/8135	0.04031	0.2179	0.1834	SLAMF1/IL1A/NFKB1/IL6/RCHY1/IL2RB/IL1B/IL12B/CBLB/CYCS/CSNK2A2/RAB9A/PIK3CA/CD3E/PIK3R1	15
KEGG	hsa04380	Osteoclast differentiation	14/537	128/8135	0.04228	0.2248	0.1891	IL1A/NFKB1/IFNG/TGFBR2/IL1B/FYN/TNF/LCK/LILRB3/PIK3CA/MAPK3/SPI1/LILRB4/PIK3R1	14
KEGG	hsa00630	Glyoxylate and dicarboxylate metabolism	5/537	30/8135	0.04449	0.2299	0.1935	MDH1/DLD/CAT/CS/ACAT1	5
KEGG	hsa04350	TGF-beta signaling pathway	11/537	94/8135	0.04469	0.2299	0.1935	MYC/IFNG/TGFBR2/SKP1/ACVR1/TNF/RBX1/BMPR1B/MAPK3/AMHR2/CUL1	11
KEGG	hsa04137	Mitophagy - animal	9/537	72/8135	0.04628	0.2343	0.1972	OPTN/RRAS/MFN1/CSNK2A2/RRAS2/UBA52/CITED2/UBB/ATG5	9
KEGG	hsa01524	Platinum drug resistance	9/537	73/8135	0.04985	0.2433	0.2047	CYCS/BIRC3/MSH2/PIK3CA/MAPK3/GSTT2/PMAIP1/GSTA3/PIK3R1	9
KEGG	hsa04710	Circadian rhythm	5/537	31/8135	0.05029	0.2433	0.2047	SKP1/RORA/CRY1/RBX1/CUL1	5
KEGG	hsa05202	Transcriptional misregulation in cancer	19/537	193/8135	0.05155	0.2433	0.2047	MYC/NFKB1/IL6/TGFBR2/IL2RB/GZMB/BIRC3/SPINT1/BCL11B/MLLT3/RARA/ELANE/TLX3/LYL1/ZBTB16/SPI1/NCOR1/MAF/IL3	19
KEGG	hsa04218	Cellular senescence	16/537	156/8135	0.05179	0.2433	0.2047	MYC/IL1A/NFKB1/IL6/TGFBR2/RRAS/CAPN1/RBBP4/SLC25A5/VDAC3/PPP1CC/ATR/PIK3CA/MAPK3/RRAS2/PIK3R1	16
KEGG	hsa03013	Nucleocytoplasmic transport	12/537	108/8135	0.05187	0.2433	0.2047	NUP107/NUP37/EIF4A3/NUP205/UPF3A/NUP85/CSE1L/NUP160/NUP214/RBM8A/UPF3B/IPO7	12
KEGG	hsa00900	Terpenoid backbone biosynthesis	4/537	22/8135	0.05318	0.2458	0.2069	PDSS1/IDI1/FNTA/ACAT1	4
KEGG	hsa04919	Thyroid hormone signaling pathway	13/537	121/8135	0.05533	0.2522	0.2122	MYC/PRKACB/ATP2A2/NCOA3/TBC1D4/PLCB3/PIK3CA/MAPK3/ATP1B1/PFKP/MED17/NCOR1/PIK3R1	13
KEGG	hsa04961	Endocrine and other factor-regulated calcium reabsorption	7/537	53/8135	0.05801	0.2606	0.2193	GNAS/PRKACB/SLC8A2/PLCB3/ATP1B1/ATP2B2/AP2B1	7
KEGG	hsa05133	Pertussis	9/537	76/8135	0.06162	0.273	0.2297	IL1A/NFKB1/IL6/CASP7/IL1B/IL12B/TNF/IL23A/MAPK3	9
KEGG	hsa03022	Basal transcription factors	6/537	45/8135	0.07353	0.3213	0.2704	GTF2A2/GTF2H3/TBP/TAF5/GTF2E1/TAF12	6
KEGG	hsa05134	Legionellosis	7/537	57/8135	0.07969	0.3435	0.2891	NFKB1/IL6/CASP7/IL1B/IL12B/CYCS/TNF	7
KEGG	hsa04714	Thermogenesis	21/537	232/8135	0.08636	0.3673	0.3091	SOS1/GNAS/PRKACB/UQCRB/NDUFV1/NDUFV2/COX11/COX6C/NDUFA10/SDHA/NDUFA4/NDUFA6/NDUFB4/CYC1/SMARCD3/LIPE/ACSL3/NDUFS1/NDUFS4/RPS6KA3/ZNF516	21
KEGG	hsa05230	Central carbon metabolism in cancer	8/537	70/8135	0.08879	0.3716	0.3127	MYC/LDHB/SLC7A5/PIK3CA/MAPK3/PFKP/PDHB/PIK3R1	8
KEGG	hsa04662	B cell receptor signaling pathway	9/537	82/8135	0.0901	0.3716	0.3127	NFKB1/SOS1/MALT1/LILRB3/PIK3CA/MAPK3/LILRB4/PIK3R1/DAPP1	9
KEGG	hsa04114	Oocyte meiosis	13/537	131/8135	0.09102	0.3716	0.3127	SKP1/PPP2R5C/CDC23/PRKACB/ANAPC5/PPP1CC/RBX1/YWHAQ/MAPK3/FBXO5/PKMYT1/CUL1/RPS6KA3	13
KEGG	hsa05131	Shigellosis	22/537	247/8135	0.09202	0.3716	0.3127	NFKB1/CCL5/ATG14/IL1B/SKP1/MALT1/PRKCQ/CAPN1/CYCS/TNF/RBX1/TRAF5/ACTN1/PLCB3/PIK3CA/MAPK3/UBA52/ELMO2/CUL1/UBB/PIK3R1/ATG5	22
KEGG	hsa05414	Dilated cardiomyopathy	10/537	96/8135	0.1005	0.4005	0.337	ITGA4/GNAS/ITGA6/PRKACB/ATP2A2/ITGA7/TNF/SLC8A2/CACNB4/ITGB4	10
KEGG	hsa04066	HIF-1 signaling pathway	11/537	109/8135	0.1041	0.4099	0.3449	NFKB1/IL6/PGK1/IFNG/LDHB/RBX1/PIK3CA/MAPK3/PFKP/PDHB/PIK3R1	11
KEGG	hsa04979	Cholesterol metabolism	6/537	50/8135	0.1095	0.4116	0.3463	CETP/LIPA/LDLRAP1/NPC1/VDAC3/LRP1	6
KEGG	hsa05144	Malaria	6/537	50/8135	0.1095	0.4116	0.3463	KLRB1/IL6/IFNG/IL1B/TNF/LRP1	6
KEGG	hsa00650	Butanoate metabolism	4/537	28/8135	0.1096	0.4116	0.3463	ABAT/OXCT1/GAD2/ACAT1	4
KEGG	hsa04072	Phospholipase D signaling pathway	14/537	148/8135	0.1098	0.4116	0.3463	SOS1/GNAS/RRAS/FYN/PLCB3/PIK3CA/MAPK3/RRAS2/SPHK2/DGKZ/AVPR1B/AGPAT2/LPAR6/PIK3R1	14
KEGG	hsa04750	Inflammatory mediator regulation of TRP channels	10/537	98/8135	0.1113	0.4116	0.3463	IL1B/PRKCH/PRKCQ/GNAS/PRKACB/PPP1CC/PLCB3/PIK3CA/PTGER4/PIK3R1	10
KEGG	hsa05210	Colorectal cancer	9/537	86/8135	0.1128	0.4116	0.3463	MYC/SOS1/TGFBR2/CYCS/MSH2/PIK3CA/MAPK3/PMAIP1/PIK3R1	9
KEGG	hsa04630	JAK-STAT signaling pathway	15/537	162/8135	0.1148	0.4116	0.3463	STAT4/MYC/SOS1/IL6/IFNG/IL2RB/IL12B/IL15RA/IL23A/PIAS4/PIK3CA/LIF/IL15/PIK3R1/IL3	15
KEGG	hsa05161	Hepatitis B	15/537	162/8135	0.1148	0.4116	0.3463	PCNA/STAT4/MYC/NFKB1/SOS1/IL6/TGFBR2/CYCS/VDAC3/TNF/YWHAQ/TLR3/PIK3CA/MAPK3/PIK3R1	15
KEGG	hsa00270	Cysteine and methionine metabolism	6/537	51/8135	0.1176	0.4118	0.3465	MDH1/LDHB/MTR/GCLC/AHCY/CBS	6
KEGG	hsa05145	Toxoplasmosis	11/537	112/8135	0.1198	0.4118	0.3465	HLA-DRB4/NFKB1/IFNG/ITGA6/IL12B/HLA-DQB1/CYCS/BIRC3/TNF/HLA-DOB/MAPK3	11
KEGG	hsa04623	Cytosolic DNA-sensing pathway	7/537	63/8135	0.1199	0.4118	0.3465	NFKB1/CCL5/IL6/IL1B/POLR1D/POLR3K/POLR3C	7
KEGG	hsa01230	Biosynthesis of amino acids	8/537	75/8135	0.12	0.4118	0.3465	PGK1/PRPS2/CS/MTR/PRPS1/OTC/CBS/PFKP	8
KEGG	hsa04061	Viral protein interaction with cytokine and cytokine receptor	10/537	100/8135	0.1227	0.4121	0.3468	CXCL11/CCL5/IL6/CCR3/IL2RB/TNF/CXCR4/CCL11/CCL25/CCL23	10
KEGG	hsa04933	AGE-RAGE signaling pathway in diabetic complications	10/537	100/8135	0.1227	0.4121	0.3468	IL1A/NFKB1/IL6/TGFBR2/IL1B/TNF/PLCB3/PIK3CA/MAPK3/PIK3R1	10
KEGG	hsa05220	Chronic myeloid leukemia	8/537	76/8135	0.1269	0.4188	0.3524	MYC/NFKB1/SOS1/TGFBR2/PIK3CA/MAPK3/PIK3R1/BCR	8
KEGG	hsa04810	Regulation of actin cytoskeleton	19/537	218/8135	0.1295	0.4188	0.3524	SOS1/CHRM5/ITGA4/ITGA6/RRAS/ITGA7/PPP1CC/CXCR4/ARHGEF7/CYFIP2/ACTN1/PIK3CA/MAPK3/RRAS2/CHRM2/ITGB4/FGF18/PIK3R1/ITGAE	19
KEGG	hsa04216	Ferroptosis	5/537	41/8135	0.1308	0.4188	0.3524	VDAC3/GCLC/PCBP1/ACSL3/ATG5	5
KEGG	hsa04727	GABAergic synapse	9/537	89/8135	0.1317	0.4188	0.3524	ABAT/PRKACB/SLC38A1/PLCL1/SLC12A5/GABRB2/GABRP/SLC38A2/GAD2	9
KEGG	hsa04062	Chemokine signaling pathway	17/537	192/8135	0.1317	0.4188	0.3524	CXCL11/NFKB1/SOS1/CCL5/CCR3/PRKACB/CXCR6/CXCR4/WAS/ITK/PLCB3/PIK3CA/MAPK3/CCL11/CCL25/CCL23/PIK3R1	17
KEGG	hsa00030	Pentose phosphate pathway	4/537	30/8135	0.1326	0.4188	0.3524	PRPS2/DERA/PRPS1/PFKP	4
KEGG	hsa05410	Hypertrophic cardiomyopathy	9/537	90/8135	0.1383	0.4266	0.3589	IL6/ITGA4/ITGA6/ATP2A2/ITGA7/TNF/SLC8A2/CACNB4/ITGB4	9
KEGG	hsa04140	Autophagy - animal	13/537	141/8135	0.1384	0.4266	0.3589	ATG14/PRKCQ/RRAS/CTSD/PRKACB/DAPK2/PIK3CA/MAPK3/RRAS2/STK11/IGBP1/PIK3R1/ATG5	13
KEGG	hsa00380	Tryptophan metabolism	5/537	42/8135	0.1409	0.4266	0.3589	DLD/CAT/KMO/KYNU/ACAT1	5
KEGG	hsa04612	Antigen processing and presentation	8/537	78/8135	0.1413	0.4266	0.3589	HLA-DRB4/IFNG/KLRD1/HLA-DQB1/CD8A/TNF/HLA-DOB/NFYB	8
KEGG	hsa00100	Steroid biosynthesis	3/537	20/8135	0.1417	0.4266	0.3589	MSMO1/LIPA/SC5D	3
KEGG	hsa04215	Apoptosis - multiple species	4/537	32/8135	0.1574	0.4693	0.3949	CASP7/CYCS/BIRC3/PMAIP1	4
KEGG	hsa04664	Fc epsilon RI signaling pathway	7/537	68/8135	0.1599	0.4722	0.3973	SOS1/FYN/TNF/PIK3CA/MAPK3/PIK3R1/IL3	7
KEGG	hsa04071	Sphingolipid signaling pathway	11/537	119/8135	0.1613	0.4722	0.3973	NFKB1/PPP2R5C/CTSD/FYN/TNF/CERS6/PLCB3/PIK3CA/MAPK3/SPHK2/PIK3R1	11
KEGG	hsa05211	Renal cell carcinoma	7/537	69/8135	0.1686	0.489	0.4114	SOS1/FLCN/RBX1/PIK3CA/MAPK3/FH/PIK3R1	7
KEGG	hsa04931	Insulin resistance	10/537	108/8135	0.1746	0.5019	0.4223	NFKB1/IL6/PRKCQ/PPP1CC/TNF/TBC1D4/PIK3CA/RPS6KA3/PIK3R1/GFPT1	10
KEGG	hsa04723	Retrograde endocannabinoid signaling	13/537	148/8135	0.1782	0.5071	0.4267	PRKACB/NDUFV1/NDUFV2/NDUFA10/NDUFA4/NDUFA6/NDUFB4/PLCB3/MAPK3/GABRB2/GABRP/NDUFS1/NDUFS4	13
KEGG	hsa05169	Epstein-Barr virus infection	17/537	202/8135	0.1796	0.5071	0.4267	CD247/HLA-DRB4/MYC/NFKB1/IL6/HLA-DQB1/PSMD14/PSMC2/CYCS/TNF/TRAF5/HLA-DOB/PSMD12/PIK3CA/CD3E/PIK3R1/PSMC5	17
KEGG	hsa03008	Ribosome biogenesis in eukaryotes	10/537	109/8135	0.1818	0.5086	0.428	DROSHA/REXO2/AK6/FBL/EMG1/MDN1/CSNK2A2/RIOK2/MPHOSPH10/PWP2	10
KEGG	hsa03020	RNA polymerase	4/537	34/8135	0.1838	0.5097	0.4289	POLR1B/POLR1D/POLR3K/POLR3C	4
KEGG	hsa04261	Adrenergic signaling in cardiomyocytes	13/537	150/8135	0.1905	0.5169	0.4349	CREM/PPP2R5C/GNAS/PRKACB/ATP2A2/PPP1CC/SLC8A2/PLCB3/MAPK3/ATP1B1/CACNB4/ATP2B2/KCNQ1	13
KEGG	hsa03060	Protein export	3/537	23/8135	0.1912	0.5169	0.4349	SRP72/OXA1L/SPCS1	3
KEGG	hsa03430	Mismatch repair	3/537	23/8135	0.1912	0.5169	0.4349	PCNA/MSH2/RPA1	3
KEGG	hsa04012	ErbB signaling pathway	8/537	85/8135	0.1973	0.5288	0.445	MYC/SOS1/NCK1/CBLB/ERBB3/PIK3CA/MAPK3/PIK3R1	8
KEGG	hsa05416	Viral myocarditis	6/537	60/8135	0.2025	0.5382	0.4529	HLA-DRB4/HLA-DQB1/PRF1/CYCS/FYN/HLA-DOB	6
KEGG	hsa05418	Fluid shear stress and atherosclerosis	12/537	139/8135	0.2063	0.5438	0.4576	IL1A/NFKB1/IFNG/IL1B/ACVR1/TNF/BMPR1B/PIAS4/PIK3CA/GSTT2/GSTA3/PIK3R1	12
KEGG	hsa04670	Leukocyte transendothelial migration	10/537	114/8135	0.2193	0.5624	0.4732	RHOH/ITGA4/CXCR4/TXK/ITK/ACTN1/PIK3CA/CD99/CLDN15/PIK3R1	10
KEGG	hsa04360	Axon guidance	15/537	182/8135	0.2208	0.5624	0.4732	NCK1/RASA1/RRAS/FYN/CXCR4/BMPR1B/PLXNB2/SEMA4G/PIK3CA/MAPK3/SEMA3G/ABLIM1/NTN1/PIK3R1/EFNB3	15
KEGG	hsa00230	Purine metabolism	11/537	128/8135	0.2237	0.5624	0.4732	PRPS2/DCK/AK6/ENPP4/PDE4B/PRPS1/ADPRM/ADSL/PDE8A/NUDT9/APRT	11
KEGG	hsa04213	Longevity regulating pathway - multiple species	6/537	62/8135	0.2238	0.5624	0.4732	CAT/PRKACB/PIK3CA/SOD1/PIK3R1/ATG5	6
KEGG	hsa04918	Thyroid hormone synthesis	7/537	75/8135	0.2246	0.5624	0.4732	GNAS/PRKACB/ASGR2/ASGR1/PLCB3/ATP1B1/GPX7	7
KEGG	hsa00250	Alanine, aspartate and glutamate metabolism	4/537	37/8135	0.2257	0.5624	0.4732	ABAT/ADSL/GAD2/GFPT1	4
KEGG	hsa01250	Biosynthesis of nucleotide sugars	4/537	37/8135	0.2257	0.5624	0.4732	UGP2/GNE/UAP1L1/GFPT1	4
KEGG	hsa05163	Human cytomegalovirus infection	18/537	225/8135	0.2299	0.5624	0.4732	MYC/NFKB1/SOS1/CCL5/IL6/CCR3/IL1B/GNAS/PRKACB/CYCS/TNF/TRAF5/CXCR4/PLCB3/PIK3CA/MAPK3/PTGER4/PIK3R1	18
KEGG	hsa04914	Progesterone-mediated oocyte maturation	9/537	102/8135	0.2302	0.5624	0.4732	CDC23/CDC25B/PRKACB/ANAPC5/PIK3CA/MAPK3/PKMYT1/RPS6KA3/PIK3R1	9
KEGG	hsa04211	Longevity regulating pathway	8/537	89/8135	0.2328	0.5624	0.4732	NFKB1/CAT/PRKACB/SESN1/PIK3CA/STK11/PIK3R1/ATG5	8
KEGG	hsa04621	NOD-like receptor signaling pathway	15/537	184/8135	0.2333	0.5624	0.4732	NFKB1/CCL5/IL6/IL1B/VDAC3/BIRC3/TNF/TRPM2/TRAF5/PSTPIP1/MFN1/DNM1L/PLCB3/MAPK3/ATG5	15
KEGG	hsa04971	Gastric acid secretion	7/537	76/8135	0.2345	0.5624	0.4732	GNAS/PRKACB/HRH2/PLCB3/CCKBR/ATP1B1/KCNQ1	7
KEGG	hsa05160	Hepatitis C	13/537	157/8135	0.2366	0.5633	0.474	MYC/NFKB1/SOS1/IFNG/CYCS/TNF/YWHAQ/TLR3/PIK3CA/RSAD2/MAPK3/CLDN15/PIK3R1	13
KEGG	hsa05340	Primary immunodeficiency	4/537	38/8135	0.2402	0.5675	0.4776	ICOS/CD8A/LCK/CD3E	4
KEGG	hsa00790	Folate biosynthesis	3/537	26/8135	0.2442	0.5694	0.4791	QDPR/AKR1B1/AKR1C3	3
KEGG	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	7/537	77/8135	0.2445	0.5694	0.4791	ITGA4/ITGA6/ATP2A2/ITGA7/SLC8A2/CACNB4/ITGB4	7
KEGG	hsa04217	Necroptosis	13/537	159/8135	0.2505	0.5791	0.4873	PARP1/STAT4/IL1A/IFNG/IL1B/CAPN1/SLC25A5/VDAC3/BIRC3/TNF/TRAF5/DNM1L/TLR3	13
KEGG	hsa05417	Lipid and atherosclerosis	17/537	215/8135	0.2531	0.5808	0.4887	NFKB1/CCL5/IL6/CASP7/IL1B/POU2F2/IL12B/CYCS/TNF/XBP1/PLCB3/PIK3CA/MAPK3/CYP2C9/TLR6/PIK3R1/LBP	17
KEGG	hsa05222	Small cell lung cancer	8/537	92/8135	0.2608	0.5942	0.5	MYC/NFKB1/ITGA6/CYCS/BIRC3/TRAF5/PIK3CA/PIK3R1	8
KEGG	hsa05320	Autoimmune thyroid disease	5/537	53/8135	0.2706	0.6111	0.5142	HLA-DRB4/HLA-DQB1/PRF1/GZMB/HLA-DOB	5
KEGG	hsa05203	Viral carcinogenesis	16/537	204/8135	0.272	0.6111	0.5142	NFKB1/CCR3/PRKACB/GTF2A2/VDAC3/TRAF5/GTF2H3/YWHAQ/ACTN1/PIK3CA/MAPK3/HDAC4/TBP/PMAIP1/GTF2E1/PIK3R1	16
KEGG	hsa04514	Cell adhesion molecules	12/537	149/8135	0.2788	0.616	0.5183	HLA-DRB4/CD2/MADCAM1/ITGA4/ITGA6/ICOS/HLA-DQB1/CD8A/HLA-DOB/MPZ/CD99/CLDN15	12
KEGG	hsa00010	Glycolysis / Gluconeogenesis	6/537	67/8135	0.28	0.616	0.5183	PGK1/LDHB/DLD/ALDH3B1/PFKP/PDHB	6
KEGG	hsa04720	Long-term potentiation	6/537	67/8135	0.28	0.616	0.5183	PRKACB/PPP1CC/PLCB3/MAPK3/RPS6KA3/GRIN2D	6
KEGG	hsa00430	Taurine and hypotaurine metabolism	2/537	16/8135	0.2855	0.6237	0.5248	ADO/GAD2	2
KEGG	hsa04024	cAMP signaling pathway	17/537	221/8135	0.2904	0.6303	0.5303	NFKB1/GNAS/RRAS/PRKACB/ATP2A2/PDE4B/PPP1CC/LIPE/PIK3CA/MAPK3/ATP1B1/RRAS2/CHRM2/ABCC4/ATP2B2/PIK3R1/GRIN2D	17
KEGG	hsa04910	Insulin signaling pathway	11/537	137/8135	0.2941	0.6339	0.5334	SOS1/PRKACB/CBLB/PPP1CC/PHKG1/LIPE/EXOC7/PRKAR2B/PIK3CA/MAPK3/PIK3R1	11
KEGG	hsa04010	MAPK signaling pathway	22/537	294/8135	0.2999	0.6386	0.5374	MYC/IL1A/NFKB1/SOS1/TGFBR2/DUSP2/IL1B/CDC25B/RASA1/RRAS/PRKACB/ERBB3/TNF/PTPN7/RASGRP1/MAPK3/RRAS2/CACNB4/MAP4K2/DAXX/FGF18/RPS6KA3	22
KEGG	hsa04611	Platelet activation	10/537	124/8135	0.3021	0.6386	0.5374	GNAS/PRKACB/P2RX1/FYN/PPP1CC/RASGRP1/PLCB3/PIK3CA/MAPK3/PIK3R1	10
KEGG	hsa04915	Estrogen signaling pathway	11/537	138/8135	0.3023	0.6386	0.5374	SOS1/GNAS/CTSD/PRKACB/KRT9/NCOA3/RARA/PLCB3/PIK3CA/MAPK3/PIK3R1	11
KEGG	hsa04923	Regulation of lipolysis in adipocytes	5/537	56/8135	0.3098	0.6391	0.5378	GNAS/PRKACB/LIPE/PIK3CA/PIK3R1	5
KEGG	hsa00120	Primary bile acid biosynthesis	2/537	17/8135	0.3105	0.6391	0.5378	SCP2/CH25H	2
KEGG	hsa00450	Selenocompound metabolism	2/537	17/8135	0.3105	0.6391	0.5378	SEPHS1/MTR	2
KEGG	hsa00910	Nitrogen metabolism	2/537	17/8135	0.3105	0.6391	0.5378	CA7/CA9	2
KEGG	hsa04917	Prolactin signaling pathway	6/537	70/8135	0.3151	0.6444	0.5422	NFKB1/SOS1/PIK3CA/MAPK3/CSN2/PIK3R1	6
KEGG	hsa01522	Endocrine resistance	8/537	98/8135	0.3194	0.649	0.5461	SOS1/GNAS/PRKACB/NCOA3/PIK3CA/MAPK3/NCOR1/PIK3R1	8
KEGG	hsa04520	Adherens junction	6/537	71/8135	0.327	0.6542	0.5505	TGFBR2/FYN/WAS/CSNK2A2/ACTN1/MAPK3	6
KEGG	hsa04725	Cholinergic synapse	9/537	113/8135	0.3292	0.6542	0.5505	CHRM5/PRKACB/FYN/PLCB3/PIK3CA/MAPK3/CHRM2/KCNQ1/PIK3R1	9
KEGG	hsa04962	Vasopressin-regulated water reabsorption	4/537	44/8135	0.3304	0.6542	0.5505	GNAS/PRKACB/DYNLL1/DCTN6	4
KEGG	hsa04150	mTOR signaling pathway	12/537	156/8135	0.3337	0.6542	0.5505	SOS1/FLCN/EIF4B/TNF/SLC7A5/PIK3CA/MAPK3/STK11/RPS6KA3/PIK3R1/FZD2/STRADA	12
KEGG	hsa00052	Galactose metabolism	3/537	31/8135	0.3362	0.6542	0.5505	UGP2/AKR1B1/PFKP	3
KEGG	hsa00410	beta-Alanine metabolism	3/537	31/8135	0.3362	0.6542	0.5505	ABAT/ALDH3B1/GAD2	3
KEGG	hsa05213	Endometrial cancer	5/537	58/8135	0.3363	0.6542	0.5505	MYC/SOS1/PIK3CA/MAPK3/PIK3R1	5
KEGG	hsa04370	VEGF signaling pathway	5/537	59/8135	0.3497	0.6703	0.564	SH2D2A/PIK3CA/MAPK3/SPHK2/PIK3R1	5
KEGG	hsa04260	Cardiac muscle contraction	7/537	87/8135	0.3507	0.6703	0.564	ATP2A2/UQCRB/COX6C/CYC1/SLC8A2/ATP1B1/CACNB4	7
KEGG	hsa04115	p53 signaling pathway	6/537	73/8135	0.3509	0.6703	0.564	RCHY1/CCNG1/SESN1/CYCS/ATR/PMAIP1	6
KEGG	hsa04972	Pancreatic secretion	8/537	102/8135	0.3598	0.6817	0.5736	CD38/GNAS/ATP2A2/PLCB3/ATP1B1/ATP2B2/PLA2G3/KCNQ1	8
KEGG	hsa04930	Type II diabetes mellitus	4/537	46/8135	0.3611	0.6817	0.5736	TNF/PIK3CA/MAPK3/PIK3R1	4
KEGG	hsa04976	Bile secretion	7/537	89/8135	0.3727	0.6883	0.5792	ABCB1/GNAS/PRKACB/ATP1B1/SLC10A2/ABCC4/SLC22A7	7
KEGG	hsa00051	Fructose and mannose metabolism	3/537	33/8135	0.3731	0.6883	0.5792	ENOSF1/AKR1B1/PFKP	3
KEGG	hsa04142	Lysosome	10/537	132/8135	0.3731	0.6883	0.5792	LIPA/CTSC/LAMP3/CTSD/NPC1/ARSA/WDR7/SGSH/MCOLN1/CTSG	10
KEGG	hsa03420	Nucleotide excision repair	4/537	47/8135	0.3765	0.6883	0.5792	PCNA/RBX1/GTF2H3/RPA1	4
KEGG	hsa04973	Carbohydrate digestion and absorption	4/537	47/8135	0.3765	0.6883	0.5792	PLCB3/PIK3CA/ATP1B1/PIK3R1	4
KEGG	hsa05205	Proteoglycans in cancer	15/537	205/8135	0.3776	0.6883	0.5792	DROSHA/MYC/SOS1/EIF4B/RRAS/PRKACB/IL12B/ERBB3/PPP1CC/TNF/PIK3CA/MAPK3/RRAS2/PIK3R1/FZD2	15
KEGG	hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	2/537	20/8135	0.3842	0.6964	0.586	CHST12/CHPF2	2
KEGG	hsa00520	Amino sugar and nucleotide sugar metabolism	4/537	49/8135	0.407	0.7255	0.6105	UGP2/GNE/UAP1L1/GFPT1	4
KEGG	hsa05030	Cocaine addiction	4/537	49/8135	0.407	0.7255	0.6105	NFKB1/GNAS/PRKACB/GRIN2D	4
KEGG	hsa00770	Pantothenate and CoA biosynthesis	2/537	21/8135	0.4081	0.7255	0.6105	PPCS/AASDHPPT	2
KEGG	hsa05322	Systemic lupus erythematosus	10/537	136/8135	0.4094	0.7255	0.6105	HLA-DRB4/IFNG/SNRPD1/HLA-DQB1/TNF/HLA-DOB/C8B/ACTN1/ELANE/CTSG	10
KEGG	hsa04970	Salivary secretion	7/537	93/8135	0.4168	0.7346	0.6181	CD38/LYZ/GNAS/PRKACB/PLCB3/ATP1B1/ATP2B2	7
KEGG	hsa01521	EGFR tyrosine kinase inhibitor resistance	6/537	79/8135	0.4231	0.7415	0.6239	SOS1/IL6/ERBB3/PIK3CA/MAPK3/PIK3R1	6
KEGG	hsa03030	DNA replication	3/537	36/8135	0.4276	0.7434	0.6255	PCNA/RPA1/MCM6	3
KEGG	hsa05170	Human immunodeficiency virus 1 infection	15/537	212/8135	0.4288	0.7434	0.6255	CD247/NFKB1/SKP1/CYCS/TNF/RBX1/TRAF5/CXCR4/ATR/PIK3CA/MAPK3/APOBEC3G/CUL1/CD3E/PIK3R1	15
KEGG	hsa00600	Sphingolipid metabolism	4/537	52/8135	0.4522	0.7787	0.6552	CERS6/ARSA/SPHK2/CERK	4
KEGG	hsa04964	Proximal tubule bicarbonate reclamation	2/537	23/8135	0.4544	0.7787	0.6552	MDH1/ATP1B1	2
KEGG	hsa04141	Protein processing in endoplasmic reticulum	12/537	171/8135	0.4565	0.7787	0.6552	SKP1/CAPN1/DERL1/RBX1/DNAJB1/XBP1/EDEM1/TRAM1/CUL1/MAN1A1/UBE2J1/SEC24A	12
KEGG	hsa04977	Vitamin digestion and absorption	2/537	24/8135	0.4767	0.7971	0.6707	LMBRD1/TCN2	2
KEGG	hsa00513	Various types of N-glycan biosynthesis	3/537	39/8135	0.4804	0.7971	0.6707	ALG13/MAN1A1/MGAT2	3
KEGG	hsa03460	Fanconi anemia pathway	4/537	54/8135	0.4817	0.7971	0.6707	USP1/ATR/FANCF/RPA1	4
KEGG	hsa04926	Relaxin signaling pathway	9/537	129/8135	0.4819	0.7971	0.6707	NFKB1/SOS1/TGFBR2/GNAS/PRKACB/PLCB3/PIK3CA/MAPK3/PIK3R1	9
KEGG	hsa04724	Glutamatergic synapse	8/537	114/8135	0.4822	0.7971	0.6707	GNAS/PRKACB/SLC38A1/PLCB3/MAPK3/SLC38A2/GRIN2D/SLC1A3	8
KEGG	hsa04920	Adipocytokine signaling pathway	5/537	69/8135	0.4822	0.7971	0.6707	NFKB1/PRKCQ/TNF/STK11/ACSL3	5
KEGG	hsa01232	Nucleotide metabolism	6/537	85/8135	0.494	0.8123	0.6835	DCK/AK6/CMPK1/UCKL1/ADSL/APRT	6
KEGG	hsa05033	Nicotine addiction	3/537	40/8135	0.4975	0.8138	0.6848	GABRB2/GABRP/GRIN2D	3
KEGG	hsa03440	Homologous recombination	3/537	41/8135	0.5143	0.8328	0.7007	TOPBP1/RPA1/XRCC2	3
KEGG	hsa05219	Bladder cancer	3/537	41/8135	0.5143	0.8328	0.7007	MYC/DAPK2/MAPK3	3
KEGG	hsa05167	Kaposi sarcoma-associated herpesvirus infection	13/537	194/8135	0.5195	0.8342	0.702	MYC/NFKB1/IL6/CCR3/ATG14/ZFP36/CYCS/TLR3/PIK3CA/MAPK3/UBA52/UBB/PIK3R1	13
KEGG	hsa05223	Non-small cell lung cancer	5/537	72/8135	0.5204	0.8342	0.702	SOS1/EML4/PIK3CA/MAPK3/PIK3R1	5
KEGG	hsa01212	Fatty acid metabolism	4/537	57/8135	0.5247	0.8347	0.7023	ACADM/SCP2/ACSL3/ACAT1	4
KEGG	hsa05226	Gastric cancer	10/537	149/8135	0.5259	0.8347	0.7023	MYC/SOS1/ABCB1/TGFBR2/MUC2/PIK3CA/MAPK3/FGF18/PIK3R1/FZD2	10
KEGG	hsa04270	Vascular smooth muscle contraction	9/537	134/8135	0.5286	0.8348	0.7024	PRKCH/PRKCQ/GNAS/PRKACB/PPP1CC/PLCB3/MAPK3/AVPR1B/PLA2G3	9
KEGG	hsa04935	Growth hormone synthesis, secretion and action	8/537	119/8135	0.5317	0.8355	0.703	SOS1/GNAS/PRKACB/PLCB3/PIK3CA/MAPK3/GHRHR/PIK3R1	8
KEGG	hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	2/537	27/8135	0.5403	0.8366	0.7039	B3GNT2/ABO	2
KEGG	hsa04152	AMPK signaling pathway	8/537	120/8135	0.5414	0.8366	0.7039	PPP2R5C/LIPE/ELAVL1/PIK3CA/STK11/PFKP/PIK3R1/STRADA	8
KEGG	hsa00071	Fatty acid degradation	3/537	43/8135	0.5469	0.8366	0.7039	ACADM/ACSL3/ACAT1	3
KEGG	hsa04975	Fat digestion and absorption	3/537	43/8135	0.5469	0.8366	0.7039	AGPAT2/PLA2G3/ACAT1	3
KEGG	hsa05225	Hepatocellular carcinoma	11/537	168/8135	0.5565	0.8366	0.7039	MYC/SOS1/BRD7/TGFBR2/SMARCD3/PIK3CA/MAPK3/GSTT2/GSTA3/PIK3R1/FZD2	11
KEGG	hsa04080	Neuroactive ligand-receptor interaction	23/537	353/8135	0.5586	0.8366	0.7039	P2RX5/CHRM5/LTB4R/P2RX1/NTSR1/GZMA/CHRNA2/HRH2/GLRA1/TRH/CCKBR/AVPR1B/CHRM2/GABRB2/PTGER4/GHRHR/P2RX6/GABRP/LPAR6/NMU/CTSG/P2RY10/GRIN2D	23
KEGG	hsa01240	Biosynthesis of cofactors	10/537	153/8135	0.5604	0.8366	0.7039	AK6/CMPK1/DLD/LIPT1/KMO/GCLC/UGP2/PPCS/ADSL/KYNU	10
KEGG	hsa05032	Morphine addiction	6/537	91/8135	0.5619	0.8366	0.7039	GNAS/PRKACB/PDE4B/GABRB2/PDE8A/GABRP	6
KEGG	hsa04730	Long-term depression	4/537	60/8135	0.566	0.8366	0.7039	PPP1R17/GNAS/PLCB3/MAPK3	4
KEGG	hsa04978	Mineral absorption	4/537	60/8135	0.566	0.8366	0.7039	SLC8A2/ATP1B1/ATP2B2/TRPM6	4
KEGG	hsa04922	Glucagon signaling pathway	7/537	107/8135	0.5661	0.8366	0.7039	LDHB/GNAS/PRKACB/PHKG1/PLCB3/PFKP/PDHB	7
KEGG	hsa05212	Pancreatic cancer	5/537	76/8135	0.5694	0.8366	0.7039	NFKB1/TGFBR2/PIK3CA/MAPK3/PIK3R1	5
KEGG	hsa04510	Focal adhesion	13/537	201/8135	0.5724	0.8366	0.7039	SOS1/ITGA4/ITGA6/ITGA7/FYN/PPP1CC/BIRC3/PARVA/ACTN1/PIK3CA/MAPK3/ITGB4/PIK3R1	13
KEGG	hsa04371	Apelin signaling pathway	9/537	139/8135	0.5737	0.8366	0.7039	RRAS/PRKACB/LIPE/SLC8A2/PLCB3/MAPK3/RRAS2/SPHK2/HDAC4	9
KEGG	hsa02010	ABC transporters	3/537	45/8135	0.5783	0.8366	0.7039	ABCD3/ABCB1/ABCC4	3
KEGG	hsa00561	Glycerolipid metabolism	4/537	61/8135	0.5793	0.8366	0.7039	DGKZ/AKR1B1/AGPAT2/AGK	4
KEGG	hsa00590	Arachidonic acid metabolism	4/537	61/8135	0.5793	0.8366	0.7039	CYP2C9/GPX7/AKR1C3/PLA2G3	4
KEGG	hsa00591	Linoleic acid metabolism	2/537	29/8135	0.5796	0.8366	0.7039	CYP2C9/PLA2G3	2
KEGG	hsa00980	Metabolism of xenobiotics by cytochrome P450	5/537	78/8135	0.5928	0.8519	0.7168	AKR7A2/CYP2C9/GSTT2/ALDH3B1/GSTA3	5
KEGG	hsa00310	Lysine degradation	4/537	63/8135	0.6052	0.8576	0.7216	DLD/PLOD1/COLGALT1/ACAT1	4
KEGG	hsa03250	Viral life cycle - HIV-1	4/537	63/8135	0.6052	0.8576	0.7216	CXCR4/MLLT3/APOBEC3G/FEZ1	4
KEGG	hsa00514	Other types of O-glycan biosynthesis	3/537	47/8135	0.6082	0.8576	0.7216	POGLUT1/COLGALT1/GALNT10	3
KEGG	hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	1/537	14/8135	0.6159	0.8576	0.7216	B3GNT2	1
KEGG	hsa04929	GnRH secretion	4/537	64/8135	0.6177	0.8576	0.7216	PLCB3/PIK3CA/MAPK3/PIK3R1	4
KEGG	hsa04666	Fc gamma R-mediated phagocytosis	6/537	97/8135	0.6251	0.8576	0.7216	WAS/PIK3CA/ASAP2/MAPK3/SPHK2/PIK3R1	6
KEGG	hsa05215	Prostate cancer	6/537	97/8135	0.6251	0.8576	0.7216	NFKB1/SOS1/SPINT1/PIK3CA/MAPK3/PIK3R1	6
KEGG	hsa04927	Cortisol synthesis and secretion	4/537	65/8135	0.6301	0.8576	0.7216	GNAS/PRKACB/PLCB3/PDE8A	4
KEGG	hsa04136	Autophagy - other	2/537	32/8135	0.6338	0.8576	0.7216	IGBP1/ATG5	2
KEGG	hsa00564	Glycerophospholipid metabolism	6/537	98/8135	0.6351	0.8576	0.7216	PNPLA6/ADPRM/GPD1L/DGKZ/AGPAT2/PLA2G3	6
KEGG	hsa04925	Aldosterone synthesis and secretion	6/537	98/8135	0.6351	0.8576	0.7216	GNAS/PRKACB/LIPE/PLCB3/ATP1B1/ATP2B2	6
KEGG	hsa05231	Choline metabolism in cancer	6/537	98/8135	0.6351	0.8576	0.7216	SOS1/WAS/PIK3CA/MAPK3/DGKZ/PIK3R1	6
KEGG	hsa04146	Peroxisome	5/537	82/8135	0.6376	0.8576	0.7216	ABCD3/CAT/SCP2/SOD1/ACSL3	5
KEGG	hsa00604	Glycosphingolipid biosynthesis - ganglio series	1/537	15/8135	0.6413	0.8576	0.7216	ST3GAL5	1
KEGG	hsa04068	FoxO signaling pathway	8/537	131/8135	0.642	0.8576	0.7216	SOS1/IL6/TGFBR2/CAT/PIK3CA/MAPK3/STK11/PIK3R1	8
KEGG	hsa04151	PI3K-Akt signaling pathway	22/537	354/8135	0.6496	0.8576	0.7216	MYC/NFKB1/SOS1/IL6/IL2RB/PPP2R5C/EIF4B/ITGA4/ITGA6/ITGA7/ERBB3/YWHAQ/MAGI1/PIK3CA/MAPK3/CHRM2/STK11/ITGB4/LPAR6/FGF18/PIK3R1/IL3	22
KEGG	hsa00510	N-Glycan biosynthesis	3/537	50/8135	0.6504	0.8576	0.7216	ALG13/MAN1A1/MGAT2	3
KEGG	hsa05110	Vibrio cholerae infection	3/537	50/8135	0.6504	0.8576	0.7216	GNAS/PRKACB/KCNQ1	3
KEGG	hsa03410	Base excision repair	2/537	33/8135	0.6506	0.8576	0.7216	PCNA/PARP1	2
KEGG	hsa04130	SNARE interactions in vesicular transport	2/537	33/8135	0.6506	0.8576	0.7216	STX8/GOSR1	2
KEGG	hsa05130	Pathogenic Escherichia coli infection	12/537	197/8135	0.6567	0.8621	0.7254	NFKB1/IL6/CASP7/IL1B/NCK1/CYCS/FYN/TNF/CYFIP2/MAPK3/CLDN15/SEC24A	12
KEGG	hsa04913	Ovarian steroidogenesis	3/537	51/8135	0.6637	0.8647	0.7276	GNAS/PRKACB/AKR1C3	3
KEGG	hsa00360	Phenylalanine metabolism	1/537	16/8135	0.665	0.8647	0.7276	ALDH3B1	1
KEGG	hsa00040	Pentose and glucuronate interconversions	2/537	34/8135	0.6668	0.8647	0.7276	UGP2/AKR1B1	2
KEGG	hsa04310	Wnt signaling pathway	10/537	167/8135	0.6718	0.8656	0.7284	MYC/SKP1/PRKACB/DAAM2/RBX1/CSNK2A2/PLCB3/CUL1/ROR1/FZD2	10
KEGG	hsa04924	Renin secretion	4/537	69/8135	0.6767	0.8656	0.7284	GNAS/PRKACB/PLCB3/PTGER4	4
KEGG	hsa05031	Amphetamine addiction	4/537	69/8135	0.6767	0.8656	0.7284	GNAS/PRKACB/PPP1CC/GRIN2D	4
KEGG	hsa04722	Neurotrophin signaling pathway	7/537	119/8135	0.6784	0.8656	0.7284	NFKB1/SOS1/MAGED1/PIK3CA/MAPK3/RPS6KA3/PIK3R1	7
KEGG	hsa04530	Tight junction	10/537	169/8135	0.6863	0.8706	0.7326	PCNA/ARHGAP17/PRKACB/RAPGEF6/WAS/CD1A/MAGI1/ACTN1/STK11/CLDN15	10
KEGG	hsa04622	RIG-I-like receptor signaling pathway	4/537	70/8135	0.6878	0.8706	0.7326	NFKB1/IL12B/TNF/ATG5	4
KEGG	hsa00760	Nicotinate and nicotinamide metabolism	2/537	36/8135	0.6974	0.8741	0.7355	CD38/NNT	2
KEGG	hsa04512	ECM-receptor interaction	5/537	88/8135	0.6987	0.8741	0.7355	ITGA4/ITGA6/ITGA7/SV2A/ITGB4	5
KEGG	hsa04540	Gap junction	5/537	88/8135	0.6987	0.8741	0.7355	SOS1/GNAS/PRKACB/PLCB3/MAPK3	5
KEGG	hsa00061	Fatty acid biosynthesis	1/537	18/8135	0.7079	0.8766	0.7376	ACSL3	1
KEGG	hsa00982	Drug metabolism - cytochrome P450	4/537	72/8135	0.709	0.8766	0.7376	CYP2C9/GSTT2/ALDH3B1/GSTA3	4
KEGG	hsa05218	Melanoma	4/537	72/8135	0.709	0.8766	0.7376	PIK3CA/MAPK3/FGF18/PIK3R1	4
KEGG	hsa05216	Thyroid cancer	2/537	37/8135	0.7118	0.8767	0.7377	MYC/MAPK3	2
KEGG	hsa04613	Neutrophil extracellular trap formation	11/537	190/8135	0.718	0.881	0.7413	NFKB1/HAT1/SLC25A5/VDAC3/PLCB3/PIK3CA/MAPK3/ELANE/HDAC4/CTSG/PIK3R1	11
KEGG	hsa00531	Glycosaminoglycan degradation	1/537	19/8135	0.7272	0.8841	0.744	SGSH	1
KEGG	hsa01210	2-Oxocarboxylic acid metabolism	1/537	19/8135	0.7272	0.8841	0.744	CS	1
KEGG	hsa04936	Alcoholic liver disease	8/537	142/8135	0.7289	0.8841	0.744	TRA2B/NFKB1/IL6/IL1B/IL12B/TNF/ACADM/LBP	8
KEGG	hsa04550	Signaling pathways regulating pluripotency of stem cells	8/537	143/8135	0.7361	0.8879	0.7472	MYC/ACVR1/BMPR1B/PIK3CA/MAPK3/LIF/PIK3R1/FZD2	8
KEGG	hsa05214	Glioma	4/537	75/8135	0.7388	0.8879	0.7472	SOS1/PIK3CA/MAPK3/PIK3R1	4
KEGG	hsa04912	GnRH signaling pathway	5/537	93/8135	0.744	0.8879	0.7472	SOS1/GNAS/PRKACB/PLCB3/MAPK3	5
KEGG	hsa00670	One carbon pool by folate	1/537	20/8135	0.7452	0.8879	0.7472	MTR	1
KEGG	hsa00240	Pyrimidine metabolism	3/537	58/8135	0.7466	0.8879	0.7472	DCK/CMPK1/UCKL1	3
KEGG	hsa05207	Chemical carcinogenesis - receptor activation	12/537	212/8135	0.7515	0.8879	0.7472	MYC/NFKB1/SOS1/GNAS/PRKACB/PIK3CA/MAPK3/GSTT2/GSTA3/FGF18/RPS6KA3/PIK3R1	12
KEGG	hsa00260	Glycine, serine and threonine metabolism	2/537	40/8135	0.7516	0.8879	0.7472	DLD/CBS	2
KEGG	hsa05100	Bacterial invasion of epithelial cells	4/537	77/8135	0.7574	0.8915	0.7502	CD2AP/PIK3CA/ELMO2/PIK3R1	4
KEGG	hsa05224	Breast cancer	8/537	147/8135	0.7633	0.8924	0.7509	MYC/SOS1/NCOA3/PIK3CA/MAPK3/FGF18/PIK3R1/FZD2	8
KEGG	hsa05165	Human papillomavirus infection	19/537	331/8135	0.7716	0.8924	0.7509	NFKB1/SOS1/PPP2R5C/ITGA4/GNAS/ITGA6/PRKACB/ITGA7/TNF/ATR/TLR3/MAGI1/PIK3CA/MAPK3/TBP/PTGER4/ITGB4/PIK3R1/FZD2	19
KEGG	hsa04070	Phosphatidylinositol signaling system	5/537	97/8135	0.7764	0.8924	0.7509	PLCB3/PIK3CA/DGKZ/PIK3C2A/PIK3R1	5
KEGG	hsa04713	Circadian entrainment	5/537	97/8135	0.7764	0.8924	0.7509	GNAS/PRKACB/PLCB3/MAPK3/GRIN2D	5
KEGG	hsa00220	Arginine biosynthesis	1/537	22/8135	0.7779	0.8924	0.7509	OTC	1
KEGG	hsa00340	Histidine metabolism	1/537	22/8135	0.7779	0.8924	0.7509	ALDH3B1	1
KEGG	hsa04726	Serotonergic synapse	6/537	115/8135	0.7797	0.8924	0.7509	GNAS/PRKACB/PLCB3/MAPK3/CYP2C9/GABRB2	6
KEGG	hsa04022	cGMP-PKG signaling pathway	9/537	167/8135	0.782	0.8924	0.7509	ATP2A2/SLC25A5/VDAC3/PPP1CC/SLC8A2/PLCB3/MAPK3/ATP1B1/ATP2B2	9
KEGG	hsa00983	Drug metabolism - other enzymes	4/537	80/8135	0.7833	0.8924	0.7509	CMPK1/UCKL1/GSTT2/GSTA3	4
KEGG	hsa04614	Renin-angiotensin system	1/537	23/8135	0.7926	0.8997	0.7571	CTSG	1
KEGG	hsa04916	Melanogenesis	5/537	101/8135	0.8056	0.9087	0.7646	GNAS/PRKACB/PLCB3/MAPK3/FZD2	5
KEGG	hsa04921	Oxytocin signaling pathway	8/537	154/8135	0.8061	0.9087	0.7646	CD38/GNAS/PRKACB/PPP1CC/TRPM2/PLCB3/MAPK3/CACNB4	8
KEGG	hsa00592	alpha-Linolenic acid metabolism	1/537	25/8135	0.8191	0.9201	0.7742	PLA2G3	1
KEGG	hsa04911	Insulin secretion	4/537	86/8135	0.8285	0.927	0.78	GNAS/PRKACB/PLCB3/ATP1B1	4
KEGG	hsa00563	Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	1/537	26/8135	0.8311	0.927	0.78	PGAP1	1
KEGG	hsa04928	Parathyroid hormone synthesis, secretion and action	5/537	106/8135	0.8378	0.928	0.7809	GNAS/PRKACB/PDE4B/PLCB3/MAPK3	5
KEGG	hsa01040	Biosynthesis of unsaturated fatty acids	1/537	27/8135	0.8423	0.928	0.7809	SCP2	1
KEGG	hsa05204	Chemical carcinogenesis - DNA adducts	3/537	69/8135	0.843	0.928	0.7809	CYP2C9/GSTT2/GSTA3	3
KEGG	hsa00565	Ether lipid metabolism	2/537	49/8135	0.8437	0.928	0.7809	GDPD3/PLA2G3	2
KEGG	hsa04014	Ras signaling pathway	12/537	232/8135	0.8479	0.9294	0.7821	NFKB1/SOS1/RASA1/RRAS/PRKACB/RASGRP1/PIK3CA/MAPK3/RRAS2/PLA2G3/FGF18/PIK3R1	12
KEGG	hsa04144	Endocytosis	13/537	251/8135	0.8547	0.9337	0.7857	FOLR3/TGFBR2/IL2RB/LDLRAP1/CBLB/CXCR4/EHD2/ASAP2/EPS15L1/VPS37B/EHD3/AP2B1/IQSEC3	13
KEGG	hsa00330	Arginine and proline metabolism	2/537	51/8135	0.8594	0.9356	0.7873	LAP3/ODC1	2
KEGG	hsa00562	Inositol phosphate metabolism	3/537	73/8135	0.8693	0.9432	0.7936	PLCB3/PIK3CA/PIK3C2A	3
KEGG	hsa03320	PPAR signaling pathway	3/537	75/8135	0.8809	0.9525	0.8015	ACADM/SCP2/ACSL3	3
KEGG	hsa05150	Staphylococcus aureus infection	4/537	96/8135	0.8863	0.9551	0.8037	HLA-DRB4/HLA-DQB1/KRT9/HLA-DOB	4
KEGG	hsa04340	Hedgehog signaling pathway	2/537	56/8135	0.8926	0.9572	0.8055	PRKACB/CUL1	2
KEGG	hsa04934	Cushing syndrome	7/537	155/8135	0.8942	0.9572	0.8055	GNAS/PRKACB/PLCB3/MAPK3/PDE8A/FH/FZD2	7
KEGG	hsa04390	Hippo signaling pathway	7/537	157/8135	0.9013	0.9616	0.8092	MYC/TGFBR2/PPP1CC/BIRC3/BMPR1B/YWHAQ/FZD2	7
KEGG	hsa00350	Tyrosine metabolism	1/537	36/8135	0.9149	0.9637	0.8109	ALDH3B1	1
KEGG	hsa00500	Starch and sucrose metabolism	1/537	36/8135	0.9149	0.9637	0.8109	UGP2	1
KEGG	hsa00512	Mucin type O-glycan biosynthesis	1/537	36/8135	0.9149	0.9637	0.8109	GALNT10	1
KEGG	hsa04974	Protein digestion and absorption	4/537	103/8135	0.9159	0.9637	0.8109	SLC8A2/ATP1B1/KCNQ1/SLC38A2	4
KEGG	hsa00140	Steroid hormone biosynthesis	2/537	61/8135	0.9184	0.9637	0.8109	HSD11B2/AKR1C3	2
KEGG	hsa05034	Alcoholism	8/537	187/8135	0.9334	0.9754	0.8208	SOS1/HAT1/GNAS/PRKACB/PPP1CC/MAPK3/HDAC4/GRIN2D	8
KEGG	hsa05168	Herpes simplex virus 1 infection	25/537	495/8135	0.9411	0.9754	0.8208	HLA-DRB4/NFKB1/CCL5/IL6/IFNG/SRSF8/IL1B/POU2F2/IL12B/HLA-DQB1/ZNF721/CYCS/PPP1CC/BIRC3/TNF/TRAF5/HLA-DOB/TLR3/ZNF571/PIK3CA/ZNF669/DAXX/ZNF45/PIK3R1/ZNF195	25
KEGG	hsa04728	Dopaminergic synapse	5/537	132/8135	0.9422	0.9754	0.8208	PPP2R5C/GNAS/PRKACB/PPP1CC/PLCB3	5
KEGG	hsa04015	Rap1 signaling pathway	9/537	210/8135	0.9422	0.9754	0.8208	GNAS/RRAS/RAPGEF6/MAGI1/PLCB3/PIK3CA/MAPK3/FGF18/PIK3R1	9
KEGG	hsa00830	Retinol metabolism	2/537	68/8135	0.9448	0.9754	0.8208	CYP2C9/RDH16	2
KEGG	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	2/537	70/8135	0.9508	0.9784	0.8232	NFKB1/CCL5	2
KEGG	hsa04721	Synaptic vesicle cycle	2/537	78/8135	0.9689	0.9938	0.8362	AP2B1/SLC1A3	2
KEGG	hsa04610	Complement and coagulation cascades	2/537	85/8135	0.9793	0.9951	0.8373	F12/C8B	2
KEGG	hsa04742	Taste transduction	2/537	86/8135	0.9805	0.9951	0.8373	PRKACB/PLCB3	2
KEGG	hsa04330	Notch signaling pathway	1/537	59/8135	0.9825	0.9951	0.8373	APH1B	1
KEGG	hsa05217	Basal cell carcinoma	1/537	63/8135	0.9867	0.9951	0.8373	FZD2	1
KEGG	hsa05206	MicroRNAs in cancer	12/537	310/8135	0.987	0.9951	0.8373	MYC/NFKB1/SOS1/ABCB1/CCNG1/CDC25B/ERBB3/RECK/PIK3CA/MAPK3/HDAC4/PIK3R1	12
KEGG	hsa00970	Aminoacyl-tRNA biosynthesis	1/537	66/8135	0.9892	0.9951	0.8373	IARS2	1
KEGG	hsa04145	Phagosome	4/537	152/8135	0.992	0.9951	0.8373	HLA-DRB4/HLA-DQB1/HLA-DOB/TLR6	4
KEGG	hsa04740	Olfactory transduction	4/537	440/8135	1	1	0.8414	PRKACB/SLC8A2/OR10H1/OR1A1	4