ONTOLOGY	ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	qvalue	geneID	Count
BP	GO:0042119	neutrophil activation	290/7096	498/18670	1.689e-20	1.09e-16	8.125e-17	FUCA1/S100A9/S100A8/SERPINA1/ITGAM/FPR2/S100A12/FPR1/ALOX5/PNP/CLEC5A/ASAH1/HK3/TLR2/QPCT/PTPN6/LILRB2/HEXB/SELL/LILRA3/RNASE2/VAT1/BST1/GPR84/GRN/ATG7/CD55/CTSA/SLC11A1/ARMC8/OLR1/AZU1/RETN/CLEC4D/GHDC/MANBA/KCNAB2/RAP1B/HSPA6/ATP8A1/MNDA/CD58/MCEMP1/MGAM/DIAPH1/CTSD/FCN1/GM2A/CKAP4/NPC2/TIMP2/CREG1/LILRB3/PLAC8/ACAA1/FCGR3B/MIF/DYNC1LI1/ACPP/CTSS/FGL2/CD93/CTSC/PPBP/CD44/LILRA2/LAMP2/SLC2A3/GSTP1/PTPRC/VCL/IL15/PSAP/DEGS1/PSMA5/ADAM8/LAMP1/CD59/PSMD11/S100P/ATP6V0C/S100A11/CLEC12A/NFKB1/IQGAP2/AGL/CST3/RAB31/ACTR2/ANXA3/PLD1/FCAR/COMMD3/STK11IP/PGAM1/PKM/CD53/ARSB/ALAD/RNASE3/TNFAIP6/PTAFR/FTL/CD36/STXBP2/MAN2B1/ITGAL/PRKCD/SLCO4C1/CFP/HBB/SERPINB1/RAP2C/OSCAR/GMFG/CD63/GCA/RAB24/PTX3/CMTM6/CFD/RHOG/ALDOC/TCIRG1/ATP11B/NBEAL2/FGR/IMPDH1/QSOX1/CAP1/GNS/ABR/CRISPLD2/CAT/ACLY/IGF2R/SCAMP1/CTSZ/PSMB1/ALDOA/RAP2B/LAMTOR1/MVP/SIRPB1/XRCC5/CCL5/GDI2/SDCBP/RAP1A/CTSB/SLC27A2/ERP44/PSMD13/CSNK2B/HMGB1/LAIR1/ATP6AP2/IDH1/AGA/PRG2/TYROBP/TRPM2/GPI/CEACAM3/RAC1/CHI3L1/DNASE1/GLA/CXCR1/PLAUR/NHLRC3/CR1/PRSS3/CYFIP1/ILF2/BIN2/DDX3X/ATP6V1D/PSMD6/BCR/GUSB/CNN2/PSMC3/PGM2/C3AR1/HPSE/HVCN1/MOSPD2/KMT2E/VNN1/ARL8A/P2RX1/MGST1/AP2A2/TMEM63A/MMP9/COTL1/ORMDL3/YPEL5/TOM1/CAND1/RAB5C/CD47/LRG1/KCMF1/PRDX6/TOLLIP/UNC13D/NRAS/DERA/DSN1/IST1/MLEC/CD300A/SRP14/CYBA/CYBB/PTPRN2/FRK/RHOF/CYB5R3/BRI3/OSTF1/GLIPR1/A1BG/CCT8/FABP5/CXCR2/IL18/PREX1/ARSA/LRRC7/NFAM1/CPNE1/PSEN1/RAB3A/MAPK1/COMMD9/APEH/PDAP1/TCN1/PRAM1/XRCC6/GAA/FUCA2/PSMA2/NEU1/CPNE3/AP1M1/HP/SLC44A2/MS4A3/TBC1D10C/TMEM30A/HSP90AB1/CTSG/FCGR2A/C6orf120/PYGL/SERPINB6/STXBP3/PSMC2/CDA/SNAP29/CD33/VCP/ANXA2/PRTN3/RHOA/IL18RAP/RAB3D/ENPP4/B4GALT1/AMPD3/LPCAT1/CEACAM8/KPNB1/SERPINB10/PSMD1/AGPAT2/PFKL/MPO/DDOST/RAB27A/SIGLEC9/PA2G4/PSMD3/PRSS2/CXCL6/PTPRJ	290
BP	GO:0002283	neutrophil activation involved in immune response	283/7096	488/18670	1.115e-19	3.599e-16	2.683e-16	FUCA1/S100A9/S100A8/SERPINA1/ITGAM/FPR2/S100A12/FPR1/ALOX5/PNP/CLEC5A/ASAH1/HK3/TLR2/QPCT/PTPN6/LILRB2/HEXB/SELL/LILRA3/RNASE2/VAT1/BST1/GPR84/GRN/ATG7/CD55/CTSA/SLC11A1/ARMC8/OLR1/AZU1/RETN/CLEC4D/GHDC/MANBA/KCNAB2/RAP1B/HSPA6/ATP8A1/MNDA/CD58/MCEMP1/MGAM/DIAPH1/CTSD/FCN1/GM2A/CKAP4/NPC2/TIMP2/CREG1/LILRB3/PLAC8/ACAA1/FCGR3B/MIF/DYNC1LI1/ACPP/CTSS/FGL2/CD93/CTSC/PPBP/CD44/LILRA2/LAMP2/SLC2A3/GSTP1/PTPRC/VCL/PSAP/DEGS1/PSMA5/ADAM8/LAMP1/CD59/PSMD11/S100P/ATP6V0C/S100A11/CLEC12A/NFKB1/IQGAP2/AGL/CST3/RAB31/ACTR2/ANXA3/PLD1/FCAR/COMMD3/STK11IP/PGAM1/PKM/CD53/ARSB/ALAD/RNASE3/TNFAIP6/PTAFR/FTL/CD36/STXBP2/MAN2B1/ITGAL/PRKCD/SLCO4C1/CFP/HBB/SERPINB1/RAP2C/OSCAR/GMFG/CD63/GCA/RAB24/PTX3/CMTM6/CFD/RHOG/ALDOC/TCIRG1/ATP11B/NBEAL2/FGR/IMPDH1/QSOX1/CAP1/GNS/ABR/CRISPLD2/CAT/ACLY/IGF2R/SCAMP1/CTSZ/PSMB1/ALDOA/RAP2B/LAMTOR1/MVP/SIRPB1/XRCC5/GDI2/SDCBP/RAP1A/CTSB/SLC27A2/ERP44/PSMD13/CSNK2B/HMGB1/LAIR1/ATP6AP2/IDH1/AGA/PRG2/TYROBP/TRPM2/GPI/CEACAM3/RAC1/CHI3L1/DNASE1/GLA/CXCR1/PLAUR/NHLRC3/CR1/PRSS3/CYFIP1/ILF2/BIN2/DDX3X/ATP6V1D/PSMD6/BCR/GUSB/CNN2/PSMC3/PGM2/C3AR1/HPSE/HVCN1/MOSPD2/VNN1/ARL8A/P2RX1/MGST1/AP2A2/TMEM63A/MMP9/COTL1/ORMDL3/YPEL5/TOM1/CAND1/RAB5C/CD47/LRG1/KCMF1/PRDX6/TOLLIP/UNC13D/NRAS/DERA/DSN1/IST1/MLEC/CD300A/SRP14/CYBA/CYBB/PTPRN2/FRK/RHOF/CYB5R3/BRI3/OSTF1/GLIPR1/A1BG/CCT8/FABP5/CXCR2/ARSA/LRRC7/NFAM1/CPNE1/PSEN1/RAB3A/MAPK1/COMMD9/APEH/PDAP1/TCN1/PRAM1/XRCC6/GAA/FUCA2/PSMA2/NEU1/CPNE3/AP1M1/HP/SLC44A2/MS4A3/TBC1D10C/TMEM30A/HSP90AB1/CTSG/FCGR2A/C6orf120/PYGL/SERPINB6/STXBP3/PSMC2/CDA/SNAP29/CD33/VCP/ANXA2/PRTN3/RHOA/RAB3D/ENPP4/B4GALT1/AMPD3/LPCAT1/CEACAM8/KPNB1/SERPINB10/PSMD1/AGPAT2/PFKL/MPO/DDOST/RAB27A/SIGLEC9/PA2G4/PSMD3/PRSS2/PTPRJ	283
BP	GO:0043312	neutrophil degranulation	281/7096	485/18670	1.802e-19	3.877e-16	2.89e-16	FUCA1/S100A9/S100A8/SERPINA1/ITGAM/FPR2/S100A12/FPR1/ALOX5/PNP/CLEC5A/ASAH1/HK3/TLR2/QPCT/PTPN6/LILRB2/HEXB/SELL/LILRA3/RNASE2/VAT1/BST1/GPR84/GRN/ATG7/CD55/CTSA/SLC11A1/ARMC8/OLR1/AZU1/RETN/CLEC4D/GHDC/MANBA/KCNAB2/RAP1B/HSPA6/ATP8A1/MNDA/CD58/MCEMP1/MGAM/DIAPH1/CTSD/FCN1/GM2A/CKAP4/NPC2/TIMP2/CREG1/LILRB3/PLAC8/ACAA1/FCGR3B/MIF/DYNC1LI1/ACPP/CTSS/FGL2/CD93/CTSC/PPBP/CD44/LAMP2/SLC2A3/GSTP1/PTPRC/VCL/PSAP/DEGS1/PSMA5/ADAM8/LAMP1/CD59/PSMD11/S100P/ATP6V0C/S100A11/CLEC12A/NFKB1/IQGAP2/AGL/CST3/RAB31/ACTR2/ANXA3/PLD1/FCAR/COMMD3/STK11IP/PGAM1/PKM/CD53/ARSB/ALAD/RNASE3/TNFAIP6/PTAFR/FTL/CD36/STXBP2/MAN2B1/ITGAL/PRKCD/SLCO4C1/CFP/HBB/SERPINB1/RAP2C/OSCAR/GMFG/CD63/GCA/RAB24/PTX3/CMTM6/CFD/RHOG/ALDOC/TCIRG1/ATP11B/NBEAL2/FGR/IMPDH1/QSOX1/CAP1/GNS/ABR/CRISPLD2/CAT/ACLY/IGF2R/SCAMP1/CTSZ/PSMB1/ALDOA/RAP2B/LAMTOR1/MVP/SIRPB1/XRCC5/GDI2/SDCBP/RAP1A/CTSB/SLC27A2/ERP44/PSMD13/CSNK2B/HMGB1/LAIR1/ATP6AP2/IDH1/AGA/PRG2/TYROBP/TRPM2/GPI/CEACAM3/RAC1/CHI3L1/GLA/CXCR1/PLAUR/NHLRC3/CR1/PRSS3/CYFIP1/ILF2/BIN2/DDX3X/ATP6V1D/PSMD6/BCR/GUSB/CNN2/PSMC3/PGM2/C3AR1/HPSE/HVCN1/MOSPD2/VNN1/ARL8A/P2RX1/MGST1/AP2A2/TMEM63A/MMP9/COTL1/ORMDL3/YPEL5/TOM1/CAND1/RAB5C/CD47/LRG1/KCMF1/PRDX6/TOLLIP/UNC13D/NRAS/DERA/DSN1/IST1/MLEC/CD300A/SRP14/CYBA/CYBB/PTPRN2/FRK/RHOF/CYB5R3/BRI3/OSTF1/GLIPR1/A1BG/CCT8/FABP5/CXCR2/ARSA/LRRC7/NFAM1/CPNE1/PSEN1/RAB3A/MAPK1/COMMD9/APEH/PDAP1/TCN1/PRAM1/XRCC6/GAA/FUCA2/PSMA2/NEU1/CPNE3/AP1M1/HP/SLC44A2/MS4A3/TBC1D10C/TMEM30A/HSP90AB1/CTSG/FCGR2A/C6orf120/PYGL/SERPINB6/STXBP3/PSMC2/CDA/SNAP29/CD33/VCP/ANXA2/PRTN3/RHOA/RAB3D/ENPP4/B4GALT1/AMPD3/LPCAT1/CEACAM8/KPNB1/SERPINB10/PSMD1/AGPAT2/PFKL/MPO/DDOST/RAB27A/SIGLEC9/PA2G4/PSMD3/PRSS2/PTPRJ	281
BP	GO:0002446	neutrophil mediated immunity	287/7096	499/18670	3.083e-19	4.974e-16	3.708e-16	FUCA1/S100A9/S100A8/SERPINA1/ITGAM/FPR2/S100A12/FPR1/ALOX5/PNP/CLEC5A/ASAH1/HK3/TLR2/QPCT/PTPN6/LILRB2/HEXB/SELL/LILRA3/RNASE2/VAT1/BST1/GPR84/GRN/ATG7/CD55/CTSA/SLC11A1/ARMC8/OLR1/AZU1/RETN/CLEC4D/GHDC/MANBA/KCNAB2/RAP1B/HSPA6/ATP8A1/MNDA/CD58/MCEMP1/MGAM/DIAPH1/CTSD/FCN1/GM2A/CKAP4/NPC2/TIMP2/CREG1/LILRB3/PLAC8/ACAA1/FCGR3B/MIF/DYNC1LI1/ACPP/CTSS/FGL2/CD93/CTSC/PPBP/CD44/LAMP2/SLC2A3/GSTP1/PTPRC/VCL/PSAP/DEGS1/PSMA5/ADAM8/LAMP1/CD59/PSMD11/S100P/ATP6V0C/S100A11/CLEC12A/NFKB1/IQGAP2/AGL/CST3/RAB31/ACTR2/ANXA3/PLD1/FCAR/COMMD3/STK11IP/PGAM1/PKM/CD53/IRAK4/ARSB/ALAD/RNASE3/TNFAIP6/PTAFR/FTL/CD36/STXBP2/MAN2B1/ITGAL/PRKCD/SLCO4C1/CFP/HBB/SERPINB1/RAP2C/OSCAR/GMFG/CD63/GCA/RAB24/PTX3/CMTM6/CFD/RHOG/ALDOC/TCIRG1/ATP11B/NBEAL2/FGR/IMPDH1/QSOX1/CAP1/GNS/ABR/CRISPLD2/CAT/ACLY/IGF2R/SCAMP1/CTSZ/PSMB1/ALDOA/RAP2B/LAMTOR1/MVP/SIRPB1/XRCC5/GDI2/SDCBP/RAP1A/CTSB/SLC27A2/ERP44/PSMD13/CSNK2B/HMGB1/LAIR1/ATP6AP2/IDH1/AGA/PRG2/TYROBP/TRPM2/GPI/CEACAM3/RAC1/CHI3L1/DNASE1/GLA/CXCR1/IL6/PLAUR/NHLRC3/CR1/PRSS3/CYFIP1/ILF2/BIN2/DDX3X/ATP6V1D/PSMD6/BCR/GUSB/CNN2/PSMC3/PGM2/C3AR1/HPSE/HVCN1/MOSPD2/KMT2E/VNN1/ARL8A/P2RX1/MGST1/AP2A2/TMEM63A/MMP9/COTL1/ORMDL3/YPEL5/TOM1/CAND1/RAB5C/CD47/LRG1/KCMF1/PRDX6/TOLLIP/UNC13D/NRAS/DERA/DSN1/IST1/MLEC/CD300A/SRP14/CYBA/CYBB/PTPRN2/FRK/RHOF/CYB5R3/BRI3/OSTF1/GLIPR1/A1BG/CCT8/FABP5/CXCR2/ADAM17/ARSA/LRRC7/NFAM1/CPNE1/PSEN1/RAB3A/MAPK1/COMMD9/APEH/PDAP1/TCN1/PRAM1/XRCC6/GAA/FUCA2/PSMA2/NEU1/CPNE3/AP1M1/HP/SLC44A2/MS4A3/TBC1D10C/TMEM30A/HSP90AB1/CTSG/FCGR2A/C6orf120/PYGL/SERPINB6/STXBP3/PSMC2/CDA/SNAP29/CD33/VCP/ANXA2/PRTN3/RHOA/RAB3D/ENPP4/B4GALT1/AMPD3/LPCAT1/CEACAM8/KPNB1/SERPINB10/PSMD1/AGPAT2/PFKL/MPO/DDOST/RAB27A/SIGLEC9/PA2G4/PSMD3/PRSS2/CXCL6/PTPRJ	287
BP	GO:0045088	regulation of innate immune response	256/7096	452/18670	3.67e-16	4.737e-13	3.531e-13	MYD88/S100A9/S100A8/ITGAM/FPR2/NOD2/FYN/ICAM2/TLR1/TLR2/PTPN6/SERPINB9/CLEC7A/APPL2/GRN/SOCS3/BCL10/LYN/IRF7/PARP9/TNIP2/IRF1/GRAMD4/WNT5A/ICAM3/CLEC4D/MNDA/PTPN2/HCK/FCN1/PSMB9/PLSCR1/CUL1/CLEC4E/MARCO/DUSP10/TNFAIP3/RPS6KA3/NLRC5/PSMB8/CTSS/BIRC2/LY96/STAT1/FLOT1/LGR4/LGMN/LILRA2/JAK2/CTSK/A2M/UBE2N/PSMA5/ADAM8/LAMP1/PSMD11/PRKACB/DDX60/IRAK3/NFKBIA/YTHDF3/GBP5/NFKB1/KRAS/APOE/PSME1/LILRB1/AIM2/TICAM1/MAPKAPK3/RELA/IFNGR2/HEXIM1/CDC37/NMI/LRP8/CD226/UBE2K/IRAK4/SIN3A/FFAR2/PAK1/PSMB10/CD36/TLR5/LEP/PSMA1/PSMA4/NR1H2/PRKCD/UBE2D3/TAB3/METTL3/HLA-F/TRAF6/IKBKG/TLR4/DDX58/PTPN22/FGR/TRAF3/UBE2D2/HLA-E/CD209/PSPC1/CACTIN/HRAS/RELB/RSAD2/CASP8/PSMB1/PAK2/PSMC4/CLEC12B/XRCC5/SAMHD1/CCL5/PLCG2/RASGRP1/DHX9/MMP12/CD300LF/CTSB/PIK3R6/PSMD13/HMGB1/MUC2/CRK/RAF1/PSMB3/SFPQ/HLA-G/MFHAS1/SERPING1/MAVS/CYLD/CR1/LSM14A/SUMO1/PUM2/PSMB5/PSMD6/TREML4/OTUD4/VSIG4/MUC1/PSMC3/RPS19/TREML2/CD96/NPLOC4/IFIH1/SEC14L1/TAB1/PSME3/MAPKAPK2/TNIP1/PSMC6/ANKRD17/HMGB2/BIRC3/NR1H3/PRKACA/NRAS/TNIP3/PVR/LAG3/IFNK/RNASEL/TLR10/CD1D/ALPK1/UBC/CD300A/LGALS9/WDFY1/CYBA/ZBP1/PGLYRP4/RAB7B/ULBP2/CRTAM/DMBT1/IFNGR1/C1QBP/VAV1/CNOT7/MUL1/KIR2DL4/FADD/GPATCH3/HSP90B1/AP1G1/TLR8/RIOK3/TIFA/MUC6/PSMC1/SOCS1/REG3G/TREM2/XRCC6/ERAP1/PSMD8/HAVCR2/PSMA2/IFNG/JAK1/NCR3/SERPINB4/TRIM15/TXK/MAP3K1/NLRX1/MUCL1/HSP90AB1/TLR3/LBP/IFNAR2/IL12B/PSMC5/SH2D1A/TRIM6/MICA/PSMC2/PSMB2/PSMD4/NCR1/POLR3F/IL18RAP/TYRO3/RTN4/UNC93B1/TSPAN6/MALT1/ADAR/TIRAP/TRAFD1/CHUK/XIAP/PSMD1/APPL1/PSMB4/ZCCHC3/HMGB4/NR1H4/NLRC3/SLAMF8/TLR6/PSMD9/PSMD3/FAM3A/RNF135/S100A14/RFTN1/MIR146A	256
BP	GO:0001819	positive regulation of cytokine production	256/7096	464/18670	2.472e-14	2.659e-11	1.982e-11	MYD88/HTR2B/NOD2/CLEC5A/CCR2/TLR1/TRIM32/TLR2/PTGER4/IL27RA/LILRB2/ANXA1/CLEC7A/BCL10/IRF7/SLC11A1/IRF1/DDX21/WNT5A/AZU1/SOD1/MNDA/CD58/IL17RA/STAT6/STAT3/FCN1/PTGS2/LILRA5/GAPDH/TNFRSF14/NLRP3/CLEC4E/CD40/MBP/MIF/CEBPG/BIRC2/CD2/LY96/STAT1/FLOT1/LILRA2/LY9/IL4R/NLRP12/CEBPB/RGCC/JAK2/PTPRC/IL15/P2RX7/EGR1/ADAM8/TNF/DDX60/CD74/HMOX1/GPRC5B/GBP5/NFKB1/IL1RAP/LILRB1/AIM2/TICAM1/ATF4/RELA/TRIM16/CD226/TGFB1/IL18R1/CCDC88B/CYP1B1/HGF/HIF1A/PTAFR/FFAR2/HSPB1/CD36/FRMD8/TLR5/PANX1/HEG1/LEP/LRRFIP1/MAPK13/FAM49B/HLA-F/TRAF6/NFKB2/HYAL2/IL20RB/TLR4/DDX58/PTPN22/FGR/HLA-DPB1/HLA-DPA1/HLA-E/PDE4B/HRAS/ABL1/RSAD2/IDO1/CASP8/IL1B/FURIN/AIF1/XRCC5/AGER/PLCG2/RASGRP1/DHX9/ARHGEF2/MMP12/POLR2L/LRP1/HMGB1/CREB1/ATP6AP2/IL7/CLU/IL1RN/TYROBP/IL6ST/NLRP9/IL1R1/HLA-G/SPTBN1/MAVS/SIGLEC16/IL6/LRRK2/POLR2H/LSM14A/GLMN/PUM2/SULF2/DDX3X/TIGIT/SPHK1/ALOX15B/C3AR1/HPSE/HDAC2/NPLOC4/IFIH1/SEC14L1/GPSM3/ADORA2B/ZNF580/PRKD2/MAPKAPK2/ANKRD17/SERPINE1/HMGB2/BIRC3/IL1A/DDX1/CASP1/OSM/IL12RB1/POLR1C/CD274/LGALS9/CYBA/ZBP1/EBI3/CYBB/FZD5/POLR2F/RAB7B/MCOLN2/ARNT/F2R/CRTAM/PLCB1/IRF8/IFNGR1/EIF2AK2/BRCA1/C1QBP/KIR2DL4/IL18/FADD/ADAM17/CD276/GPATCH3/TRAF2/POLR3E/TNFSF4/NFAM1/PSEN1/TLR8/POLR2K/RIOK3/TREM2/IL17B/XRCC6/NLRP1/RORA/HAVCR2/TSLP/IFNG/MAPK11/NR4A3/TRIM15/TXK/CD34/CD4/NLRX1/TLR3/LBP/NLRP2/TNFRSF13C/IL12B/TRIM6/ZBTB20/PRKCZ/CD80/CSF1R/AGPAT1/PRKCQ/SCAMP5/POLR3F/TRPV4/APP/CX3CL1/CD83/TSPAN6/CCL19/MALT1/TIRAP/POLR3GL/CHUK/CD244/CCR7/CD3E/AGPAT2/ROCK2/APPL1/AKIRIN2/IL26/ZCCHC3/HMGB4/IL17RB/IL23A/SERPINF2/TLR6/C1QTNF3/POLR3K/IL17RC/RNF135/IGHD/PTPRJ/IL37	256
BP	GO:0042110	T cell activation	249/7096	464/18670	3.15e-12	2.904e-09	2.165e-09	IGF1/NOD2/PNP/CCR2/FYN/PTGER4/RAC2/NFKBIZ/PTPN6/LILRB2/ANXA1/APBB1IP/CLEC7A/ELF4/BCL10/LYN/CD55/SLC11A1/IRF1/TSC1/CSK/SOD1/ARG2/CLEC4D/JMJD6/GPNMB/EGR3/STAT6/STAT3/PTPN2/CCND3/SOX13/TNFRSF14/BCL6/NLRP3/CLEC4E/SH3RF1/SMAD7/SLC46A2/DUSP10/CD1C/CD2/LFNG/FGL2/CD44/LY9/IL4R/CEBPB/CBFB/MAP3K8/PTPRC/IL15/P2RX7/EGR1/HFE/ADAM8/BATF/CD74/TNFRSF21/PRELID1/FUT7/LILRB1/DPP4/DUSP3/IL7R/DOCK8/TGFB1/PPP3CB/IL18R1/CCDC88B/PAK1/SOCS5/PSMB10/LEP/ITGAL/TNFSF13B/SRF/METTL3/FAM49B/CORO1A/LILRB4/TRAF6/ZBTB1/CLC/TCIRG1/SEMA4A/IL20RB/PTPN22/ZBTB7B/SOCS6/HLA-DPB1/HLA-DPA1/HLA-E/NCK1/DTX1/CD209/CASP3/RELB/ABL1/RSAD2/IDO1/NFKBID/CASP8/PAK2/IL1B/CD151/AIF1/SIRPB1/AGER/CD3D/CCL5/RASGRP1/RASAL3/CLPTM1/PIK3R6/HLA-DMB/ICOSLG/HMGB1/EFNB1/IGFBP2/IL7/TNFRSF18/IL6ST/TESPA1/HLA-G/RAC1/RAB29/ITK/IL6/LCK/CYLD/CR1/FLOT2/CTLA4/GLMN/MYH9/PRR7/PATZ1/TIGIT/VSIG4/AZI2/SCGB1A1/TREML2/VNN1/PDCD1LG2/LCP1/NRARP/BCL2/BMP4/BAX/CYP26B1/NFATC2/PIK3CD/CD47/CCR6/LGALS1/LAG3/IFNK/GPR18/CD3G/CD1D/IL12RB1/GRB2/CD300A/CD274/LGALS9/LAX1/EBI3/ICOS/LIG4/BTN2A2/FZD5/HES1/ADA/HLX/RHOH/THEMIS/VAV1/IL18/FADD/AP3B1/ADAM17/BCL11B/CD276/PREX1/TFRC/TNFSF4/WNT1/SART1/KAT2A/PSEN1/BTN3A1/PAG1/CD7/MSN/SOCS1/SIRPG/BAD/ZFP36L2/TNFRSF4/RORA/HAVCR2/CTPS1/IFNG/SPTA1/CD5/ATP7A/TNFSF18/FANCD2/CD4/PIK3CG/FZD7/TNFRSF13C/IL12B/DROSHA/SLA2/EIF2AK4/MICA/PRKCZ/CD80/TBX21/MTOR/PRKCQ/FOXP1/RHOA/GPR183/FOXN1/FANCA/CD83/SOX4/CCL19/MALT1/ZBTB16/CD8A/CCR7/WAS/TNFSF8/CD3E/PDCD1/GJA1/DDOST/NLRC3/TWSG1/CDH26/CD24/RAB27A/IL23A/HLA-DOA/LAT	249
BP	GO:0002703	regulation of leukocyte mediated immunity	122/7096	201/18670	5.043e-11	4.069e-08	3.033e-08	ITGAM/NOD2/CCR2/RAC2/PTPN6/IL27RA/SERPINB9/STX7/LYN/MAD2L2/DDX21/STAT6/BCL6/NLRP3/SMAD7/CD40/CD1C/IL4R/PTPRC/P2RX7/CD1E/HFE/LAMP1/TNF/HMOX1/C12orf4/LILRB1/TICAM1/IL7R/CD226/TGFB1/PPP3CB/STXBP1/IL18R1/PTAFR/STXBP2/LEP/FAM49B/HLA-F/TRAF6/ZBTB1/CLC/IL20RB/TLR4/DDX58/FGR/ABR/HLA-E/HLA-B/RSAD2/IL1B/CLEC12B/FBXO38/AGER/RASGRP1/CD1B/PIK3R6/HMGB1/CRK/TRPM4/IL1R1/HLA-G/DNASE1/MAVS/IL6/CR1/HLA-C/BCR/CD96/ADORA2B/FCER2/MLH1/PARP3/CLCF1/UNC13D/PVR/LAG3/DDX1/CD1D/IL12RB1/CD1A/CD300A/LGALS9/FER/RABGEF1/FZD5/ULBP2/CRTAM/VAV1/KIR2DL4/IL18/FADD/TRAF2/TFRC/TNFSF4/AP1G1/IL13RA2/PRAM1/CD84/HLA-A/HAVCR2/NCR3/SERPINB4/EXOSC3/TLR3/SNX4/IL12B/SH2D1A/MICA/PRKCZ/TBX21/NCR1/IL18RAP/APLF/EXOSC6/MALT1/FOXF1/WAS/PAXIP1/ATAD5/IL23A/CXCL6	122
BP	GO:0045089	positive regulation of innate immune response	206/7096	381/18670	9.803e-11	6.391e-08	4.765e-08	MYD88/S100A9/S100A8/ITGAM/FPR2/NOD2/FYN/ICAM2/TLR1/TLR2/CLEC7A/APPL2/BCL10/LYN/IRF7/PARP9/TNIP2/IRF1/GRAMD4/WNT5A/ICAM3/CLEC4D/MNDA/HCK/FCN1/PSMB9/PLSCR1/CUL1/CLEC4E/MARCO/TNFAIP3/RPS6KA3/NLRC5/PSMB8/CTSS/BIRC2/LY96/FLOT1/LGR4/LGMN/LILRA2/CTSK/UBE2N/PSMA5/ADAM8/LAMP1/PSMD11/PRKACB/DDX60/IRAK3/NFKBIA/GBP5/NFKB1/KRAS/PSME1/AIM2/TICAM1/MAPKAPK3/RELA/HEXIM1/CD226/UBE2K/IRAK4/SIN3A/FFAR2/PAK1/PSMB10/CD36/TLR5/PSMA1/PSMA4/PRKCD/UBE2D3/TAB3/HLA-F/TRAF6/IKBKG/TLR4/DDX58/PTPN22/TRAF3/UBE2D2/HLA-E/CD209/PSPC1/CACTIN/HRAS/RELB/RSAD2/CASP8/PSMB1/PAK2/PSMC4/XRCC5/CCL5/PLCG2/RASGRP1/DHX9/MMP12/CD300LF/CTSB/PSMD13/HMGB1/MUC2/RAF1/PSMB3/SFPQ/HLA-G/MFHAS1/MAVS/CYLD/LSM14A/PUM2/PSMB5/PSMD6/TREML4/OTUD4/MUC1/PSMC3/RPS19/NPLOC4/IFIH1/SEC14L1/TAB1/PSME3/MAPKAPK2/TNIP1/PSMC6/ANKRD17/HMGB2/BIRC3/NR1H3/PRKACA/NRAS/TNIP3/PVR/LAG3/IFNK/TLR10/CD1D/ALPK1/UBC/CD300A/WDFY1/CYBA/ZBP1/PGLYRP4/RAB7B/ULBP2/CRTAM/DMBT1/C1QBP/VAV1/KIR2DL4/FADD/GPATCH3/HSP90B1/AP1G1/TLR8/RIOK3/TIFA/MUC6/PSMC1/REG3G/XRCC6/PSMD8/HAVCR2/PSMA2/NCR3/TRIM15/TXK/MAP3K1/NLRX1/MUCL1/TLR3/LBP/IL12B/PSMC5/SH2D1A/TRIM6/MICA/PSMC2/PSMB2/PSMD4/POLR3F/IL18RAP/TYRO3/RTN4/UNC93B1/TSPAN6/MALT1/TIRAP/CHUK/XIAP/PSMD1/APPL1/PSMB4/ZCCHC3/HMGB4/NR1H4/TLR6/PSMD9/PSMD3/S100A14/RFTN1/MIR146A	206
BP	GO:0006732	coenzyme metabolic process	216/7096	403/18670	1.003e-10	6.391e-08	4.765e-08	IGF1/CBFA2T3/ACOT13/TALDO1/HK3/NAMPT/QPRT/PDK4/GCH1/BST1/LDHA/FBP1/PARP9/PGK1/MMADHC/CBR4/MDH1/MTHFD2/KCNAB2/SLC23A2/STAT3/PFKFB3/NUP62/NUP160/PFKM/PTGS2/PFKP/FAR2/GAPDH/HMGCL/PANK2/AHCY/NUP214/ACOT7/NMNAT3/FOLR2/ACSL5/SLC2A3/SLC2A6/ME1/ACSM5/P2RX7/PCBD1/ELOVL5/NUPR1/HMGCR/PGAM1/PKM/PDK2/GALK1/RPE/NFS1/EIF6/TPI1/ZBTB7A/TKT/HMGCS1/NUP85/ACOT9/HIF1A/COQ7/APIP/COQ5/SCD/SEH1L/OXSM/PANK3/BTD/AKR1A1/INSR/CYB5A/ALDOC/MBIP/PANK1/NUP43/RPIA/ACSL4/ACLY/NMNAT1/ENO1/MTRR/IDO1/GCLC/ENOPH1/GSTO1/ALDOA/GSTZ1/MCEE/PARP16/NADK2/PDSS1/TECR/POM121/HSD17B4/MPC2/QDPR/ACACB/RFK/OGDH/TPK1/COQ3/IDH1/ELOVL7/MOCS2/GPI/DGAT2/PTS/LDHB/G6PD/PFKFB4/PPARGC1A/MLYCD/IDH2/MCCC1/KYNU/HAAO/SPR/DHTKD1/ACSL6/PDZD11/SLC25A12/PGM2/SHMT2/VNN1/PRKAG2/MYOG/NCOR1/PCCB/CBR3/PFKFB1/ATIC/NUP88/HDAC4/THEM4/MDH1B/COQ10B/DERA/COQ9/NUP107/PDK1/GAMT/NMRK2/SLC46A1/TYMS/SLC5A6/PDHB/COQ6/FOXK2/FAR1/NMNAT2/DDIT4/CYB5R3/FLAD1/PGK2/PFKFB2/MOCS3/SUCLG2/AHCYL2/ARNT/DLAT/SHMT1/AHCYL1/PDP2/NUDT7/DHFR/AASDHPPT/PPARA/NUP93/IDO2/DBI/SLC5A8/PRKAA1/PSEN1/PDHA2/NUP205/ENO2/THTPA/SLC25A16/SLC4A1/FPGS/NUP50/IFNG/PRKAG1/OGT/PGD/PDP1/ALDH1L1/ESRRB/CROT/ZBTB20/VCP/PC/PCBD2/ADPGK/ME2/APP/FMO2/SNCA/COQ10A/ELOVL6/SLC25A32/COQ4/ABCD1/PDPR/VNN3/PFKL/NNT/TDO2/MAT1A/POM121C/AAAS/HSD17B12/PGLS/ACOT8/PIPOX/RBKS	216
BP	GO:0030098	lymphocyte differentiation	193/7096	353/18670	1.089e-10	6.391e-08	4.765e-08	PNP/CCR2/PTGER4/NFKBIZ/PTPN6/LILRB2/DLL1/ANXA1/SPI1/KLF6/NOTCH2/RBPJ/IRF1/TSC1/SOD1/CLEC4D/JMJD6/EGR3/STAT6/STAT3/PTPN2/SOX13/RNF41/BCL6/NLRP3/CLEC4E/SH3RF1/SMAD7/SLC46A2/DUSP10/CEBPG/CD2/LFNG/FGL2/LY9/IL4R/CBFB/PTPRC/IL15/EGR1/ADAM8/BATF/DOCK10/CD74/PRELID1/FUT7/IL7R/AXL/ZBTB7A/TGFB1/PPP3CB/IL18R1/POU2F2/SOCS5/PTK2B/LEP/SRF/METTL3/LILRB4/ZBTB1/FLT3LG/TCIRG1/SEMA4A/ITGA4/PTPN22/FLT3/ZBTB7B/FZD9/GON4L/DTX1/RELB/ABL1/RSAD2/NFKBID/CD3D/PLCG2/ITM2A/RASGRP1/CLPTM1/PIK3R6/TPD52/HMGB1/IL7/TNFRSF18/BLNK/TESPA1/HLA-G/TOX/ITK/IL6/LCK/CYLD/CR1/CTLA4/ATM/PRR7/PATZ1/IKZF1/LYL1/FNIP1/VNN1/NRARP/BCL2/BMP4/BAX/CYP26B1/NFATC2/HDAC4/PIK3CD/ID2/MS4A1/CLCF1/CCR6/LGALS1/LAG3/IFNK/GPR18/CR2/PPP2R3C/INHBA/CD3G/CD1D/IL12RB1/LGALS9/LIG4/PGLYRP4/BTN2A2/FZD5/MMP14/DNAJB9/ADA/HLX/RHOH/THEMIS/LRRC8A/VAV1/ITFG2/IL18/FADD/AP3B1/ADAM17/BCL11B/DOCK11/CDH17/PREX1/TNFSF4/NFAM1/WNT1/SART1/KAT2A/MERTK/SOCS1/BAD/ZFP36L2/DCLRE1C/RORA/PLCL2/IFNG/HNF1A/ATP7A/FANCD2/PCID2/CD4/INHA/FZD7/IL12B/DROSHA/PRKCZ/CD80/TBX21/MTOR/HDAC5/FOXP1/RHOA/TYRO3/GPR183/FOXN1/FANCA/CD83/SOX4/CCL19/IKZF3/MALT1/BAK1/ZBTB16/CD8A/CCR7/TNFSF8/CD3E/SLAMF8/IL23A/HLA-DOA/PTPRJ	193
BP	GO:0051188	cofactor biosynthetic process	180/7096	326/18670	1.593e-10	8.4e-08	6.263e-08	IGF1/CBFA2T3/FYN/HK3/NAMPT/QPRT/PDK4/GCH1/LDHA/FBP1/GCLM/PARP9/PGK1/MMADHC/SOD1/CBR4/STAT3/PFKFB3/NUP62/NUP160/PFKM/PTGS2/PFKP/GAPDH/FECH/PANK2/NUP214/ACOT7/NMNAT3/ACSL5/MGST2/SLC2A6/P2RX7/SLC7A11/PCBD1/ELOVL5/NUPR1/UROD/PGAM1/PKM/PDK2/GALK1/NFS1/EIF6/TPI1/GGCT/ZBTB7A/NUP85/ALAD/HIF1A/COQ7/COQ5/SCD/SEH1L/PANK3/AKR1A1/INSR/ALDOC/MBIP/ABCB6/MPV17L/PANK1/NUP43/ACSL4/ACLY/NMNAT1/ENO1/IDO1/GCLC/CPOX/ALDOA/GSTZ1/TMEM14C/PARP16/NADK2/PDSS1/SRRD/TECR/POM121/MPC2/QDPR/ACACB/RFK/OGDH/TPK1/COQ3/HAGH/ELOVL7/MOCS2/GPI/PTS/BDH2/PFKFB4/PPARGC1A/MLYCD/IDH2/KYNU/HAAO/SPR/DHTKD1/ACSL6/MMAB/PRKAG2/MYOG/NCOR1/CYP1A2/MMACHC/PFKFB1/ATIC/NUP88/HDAC4/COQ10B/COQ9/NUP107/GSS/PDK1/CNDP2/NMRK2/COX15/PDHB/COQ6/FOXK2/CYBA/CYBB/NMNAT2/DDIT4/FLAD1/IREB2/PGK2/PFKFB2/MOCS3/ARNT/DLAT/NFE2L2/NFE2L1/PDP2/DHFR/PPARA/NUP93/RSAD1/IDO2/MAOB/SLC5A8/GGT7/PRKAA1/PSEN1/PDHA2/NUP205/GGT5/ENO2/SLC25A16/SLC4A1/FPGS/ALAS1/NUP50/IFNG/PRKAG1/SPTA1/OGT/PDP1/DUOXA1/CHAC2/ESRRB/ZBTB20/PCBD2/ADPGK/APP/SNCA/COQ10A/ELOVL6/COQ4/SLC25A38/SLC25A39/PDPR/PFKL/CTNS/MAT1A/POM121C/AAAS/HSD17B12	180
BP	GO:0051222	positive regulation of protein transport	222/7096	418/18670	1.692e-10	8.4e-08	6.263e-08	IGF1/ITGAM/HTR2B/NOD2/CLEC5A/FYN/TLR1/EZR/TLR2/KCNN4/PTGER4/RAC2/ARF6/PINK1/WNT5A/CD58/IL17RA/OAZ2/FCN1/PTGS2/LILRA5/GAPDH/TNFRSF14/NLRP3/CLEC4E/PPARD/CHP1/HPS4/FLNA/MBP/MIF/CIB1/CD2/WLS/FBXW7/LILRA2/IL4R/NLRP12/RGCC/JAK2/P2RX7/BCAP31/ADAM8/TNF/C2CD5/IL1RAP/RAN/GSK3B/AIM2/EDEM1/HCLS1/TRIM16/CSNK2A2/TGFB1/PPP3CB/EXOC1/MIEF1/AACS/UNC13B/FIS1/ARRB1/HIF1A/SAR1B/FFAR2/PAK1/FRMD8/PCM1/PANX1/LEP/PRKCD/UBE2D3/CEP131/HYAL2/MCU/HTRA2/TLR4/DDX58/PTPN22/FGR/HLA-E/CDK5/SFN/HRAS/ABL1/EMD/ZPR1/IL1B/AIF1/AGER/CNST/UBR5/RASGRP1/DHX9/C2CD2L/MMP12/MPC2/ATG13/LRP1/HMGB1/TRPM4/DOC2B/GPI/RAC1/GLUD1/RAB29/SPTBN1/MAVS/IL6/IRS2/EDEM2/LRRK2/MYO1C/RHOU/PDCD5/GLMN/SERP1/SRI/SAR1A/ARF1/OXCT1/ALOX15B/ARIH2/PLK3/IFIH1/ABLIM3/RPH3AL/GOLPH3L/GPR27/BCAS3/MICALL2/TSG101/ABCG1/KIF20B/PRKACA/IL1A/CASP1/SYTL4/OSM/UBL4B/CD274/PDX1/LGALS9/TM7SF3/SREBF2/FZD5/CD2AP/PFKFB2/F2R/DNM1L/HSPA1L/CRTAM/CEMIP/IFNGR1/EGFR/ADAM9/TNFSF4/RIOK2/GIPR/PRKAA1/PSEN1/TLR8/MDM2/MAPK1/TCF7L2/SH3GLB1/YWHAE/BAD/TREM2/PLA2G6/TNFRSF4/FRMD4A/UBL5/TGFB3/NLRP1/HAVCR2/TSLP/RUFY3/IFNG/MAPK11/BAP1/CHP2/KIF5B/B3GAT3/TMEM30A/CD34/CACNB3/NLRP2/TRIM6/CD33/PRKCZ/CSF1R/SCAMP5/TRPV4/ITGB1BP1/SOX4/PDCD10/CCL19/TM9SF4/CHUK/CD244/GCG/ICE1/XPO4/NLGN2/IL26/GJA1/SMO/SEC24A/HMGB4/IL17RB/NR1H4/TARDBP/UCN3/RBP4/PSMD9/C1QTNF3/IL17RC/CTDSPL2/GHRL/IGHD/SEC16B/PHPT1	222
BP	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	222/7096	419/18670	2.256e-10	1.009e-07	7.52e-08	CBFA2T3/WWP1/ARMC8/RNF103/PSMB9/CUL1/SMAD7/FBXO6/KEAP1/PSMB8/HECTD3/DDRGK1/BIRC2/SIAH1/FBXW7/UCHL1/BCAP31/PSMA5/HFE/RAD23B/PSMD11/FHIT/KLHL15/KCTD17/SKP2/TRIM13/RYBP/GSK3B/PSME1/PLAA/RNF19B/FBXL5/TMEM129/EDEM1/UBE4B/UBE3A/UBE2K/SGTA/ARRB1/WFS1/UBE2S/KCTD10/SEC61B/ZFAND2A/SOCS5/PSMB10/PSMA1/PSMA4/CSNK1D/ERLIN1/UBE2D3/RNF217/FBXO45/DDB1/RNF175/FBXL20/CEBPA/UBXN2B/HSPA5/IFI27/PLK2/KLHL22/ANKIB1/GCLC/PSMB1/PSMC4/FOXRED2/HERC2/FBXO38/NSFL1C/SDCBP/UBE2J1/UBE2W/ARAF/ERLIN2/PML/UBE2E1/PSMD13/UBE2A/FBXL18/CLU/PSMB3/FBXL4/RBCK1/SIRT1/PCNP/UCHL5/UBE2G2/EDEM2/LRRK2/NHLRC3/CDC23/PPP2R5C/SUMO1/FBXL3/GLMN/PSMB5/RNF7/HSPBP1/PSMD6/CSNK1A1/CSNK1E/ANAPC5/BUB3/PSMC3/UBXN8/ARIH2/PLK3/NPLOC4/KAT5/PSME3/STT3B/UBQLN2/NEDD4/PSMC6/ANAPC7/RNF126/TRIB2/UBR3/MAN1B1/DNAJC10/DERL1/BBS7/UBC/DET1/PCBP2/SPSB1/NKD2/RFFL/KLHL40/UBE2C/CD2AP/DNAJB9/GID4/DERL2/STUB1/NFE2L2/FBXO4/ATXN3/COMMD1/CDC26/SPSB2/YOD1/WWP2/SPOPL/CLOCK/HSP90B1/USP7/DVL1/MAP1A/BFAR/PSEN1/MDM2/FBXL6/UBR1/FBXL2/PSMC1/CUL2/ANAPC4/PSMD8/TMUB2/UBXN1/PSMA2/ARNTL/FBXL7/ZNRF1/CDC27/OGT/FBXO27/CDC20/RNF4/FBXO44/CUL4B/RNF185/HSP90AB1/CLEC16A/LRRC29/RNF5/AGAP3/TBL1X/PSMC5/FOXF2/UBE2G1/FBXL17/PSMC2/PSMB2/PSMD4/VCP/KCTD5/FBXL14/TBX21/TOPORS/FBXL19/AURKA/ANAPC11/RNF216/RBX1/BAG5/KLHL42/USP19/SMARCC1/EDEM3/PSMD1/CHFR/ATXN3L/UBE2B/WNT10B/PSMB4/FBXL12/PSMD9/KIF14/DNAJC18/PSMD3/FBXL16/UBXN11/ERLEC1/SIAH2/OS9/CCNF/NEMF/MAPK9/ERCC8	222
BP	GO:0010498	proteasomal protein catabolic process	248/7096	477/18670	2.344e-10	1.009e-07	7.52e-08	CBFA2T3/TMTC3/PINK1/WWP1/ARMC8/RNF103/PSMB9/CUL1/RNF41/ENC1/SMAD7/PMAIP1/FBXO6/KEAP1/PSMB8/HECTD3/DDRGK1/BIRC2/SIAH1/FBXW7/UCHL1/RNF139/LAMP3/BCAP31/PSMA5/HFE/RAD23B/PSMD11/FHIT/KLHL15/KCTD17/NUPR1/SKP2/TRIM13/RYBP/APOE/GSK3B/PSME1/PLAA/RNF19B/FBXL5/TMEM129/EDEM1/UBE4B/UBE3A/UBE2K/ALAD/SGTA/ARRB1/WFS1/UBE2S/KCTD10/SEC61B/ZFAND2A/SOCS5/PSMB10/PSMA1/PSMA4/CSNK1D/ERLIN1/UBE2D3/RNF217/FBXO45/DDB1/RNF175/FBXL20/SOCS6/CEBPA/UBXN2B/HSPA5/IFI27/PLK2/KLHL22/ANKIB1/GCLC/OPHN1/PSMB1/PSMC4/FOXRED2/HERC2/FBXO38/NSFL1C/SDCBP/UBE2J1/UBE2W/ARAF/ERLIN2/PML/UBE2E1/PSMD13/UBE2A/FBXL18/CLU/PSMB3/FBXL4/RBCK1/SIRT1/PCNP/UCHL5/UBE2G2/SDF2L1/EDEM2/LRRK2/NHLRC3/CDC23/PPP2R5C/SUMO1/FBXL3/GLMN/PSMB5/RNF7/HSPBP1/PSMD6/CSNK1A1/CSNK1E/ANAPC5/RNFT1/BUB3/PSMC3/TOR1A/UBXN8/ARIH2/PLK3/NPLOC4/KAT5/PSME3/STT3B/UBQLN2/NEDD4/PSMC6/ANAPC7/RNF126/TRIB2/PRKACA/UBR3/MAN1B1/DNAJC10/DERL1/GET4/BBS7/UBC/DET1/PCBP2/SPSB1/NKD2/RFFL/KLHL40/UBE2C/CD2AP/DNAJB9/GID4/DERL2/STUB1/NFE2L2/FBXO4/ATXN3/COMMD1/NFE2L1/CDC26/SPSB2/YOD1/WWP2/SPOPL/BAG2/CLOCK/HSP90B1/USP7/DVL1/MAP1A/BFAR/POMT2/PSEN1/FMR1/MDM2/FBXL6/UBR1/FBXL2/PSMC1/CUL2/TREM2/ANAPC4/PSMD8/TMUB2/UBXN1/PSMA2/ARNTL/FBXL7/ZNRF1/CDC27/OGT/FBXO27/CDC20/RNF4/FBXO44/CUL4B/RNF185/HSP90AB1/CLEC16A/LRRC29/RNF5/AGAP3/PRPF19/TBL1X/PSMC5/FOXF2/UBE2G1/FBXL17/PSMC2/GPX1/PSMB2/PSMD4/VCP/KCTD5/FBXL14/TBX21/TOPORS/FBXL19/AURKA/ANAPC11/RNF216/RBX1/BAG5/KLHL42/USP19/SMARCC1/EDEM3/KCNE2/PSMD1/CHFR/ATXN3L/UBE2B/WNT10B/PSMB4/FBXL12/PSMD9/KIF14/DNAJC18/PSMD3/FBXL16/UBXN11/ERLEC1/SIAH2/OS9/CCNF/NEMF/MAPK9/ERCC8/RHBDF1	248
BP	GO:0062012	regulation of small molecule metabolic process	238/7096	459/18670	7.479e-10	3.017e-07	2.249e-07	NQO1/IGF1/VDR/CBFA2T3/ATP2B4/PDK4/ANXA1/APPL2/PINK1/FBP1/PGK1/POR/STARD4/SOD1/STAT3/PTPN2/PFKFB3/NUP62/OAZ2/NFYC/NUP160/GPAM/PTGS2/PSMB9/PMAIP1/ADIPOR1/PSMB8/SIRT4/PANK2/RDH10/NUP214/SIK1/SLC45A3/COX11/APOC1/SQLE/SLC2A6/ME1/P2RX7/EGR1/PSMA5/TNF/PSMD11/SLC7A11/CD74/ELOVL5/CD320/NUPR1/AKR1C3/NFKB1/RAN/APOE/GSK3B/HMGCR/PSME1/LPGAT1/KAT2B/PGAM1/PDK2/DYRK2/EIF6/ZBTB7A/TGFB1/SLC7A7/HMGCS1/NUP85/HIF1A/PTAFR/SCD/ISCU/PSMB10/SEH1L/IGFBP4/PTK2B/LEP/PSMA1/PPP1R3E/PSMA4/NR1H2/ERLIN1/INSR/P2RY6/PPP1R3D/DDB1/NUP43/OAZ3/BMP2/ENO1/DNAJC30/PSMB1/GSTZ1/IL1B/ODC1/PSMC4/UQCC2/LDLR/LMF1/ERLIN2/POM121/SLC35B4/FDPS/ACACB/PSMD13/COQ3/PSMB3/SIRT1/DGAT2/FABP3/IRS2/PDGFB/PFKFB4/DUSP12/PPARGC1A/FGF1/ARV1/FLCN/MLYCD/NLN/GNB3/TM7SF2/APOA5/LCMT1/PSMB5/COX7A2L/PSMD6/PSMC3/SLC25A12/SHMT2/IDI1/PRKAG2/MYOG/NCOR1/BMP5/KHK/PSME3/ADORA2B/SIRT5/PFKFB1/SCAP/PSMC6/NUP88/INPP5K/HDAC4/PPP1R3B/ABCG1/NR1H3/BHMT/SC5D/NUP107/PDK1/PPP1R3F/TYSND1/CPT1A/PLEK/FOXK2/AZIN1/SREBF2/DDIT4/ACADVL/PGK2/PFKFB2/ZMPSTE24/ARNT/DNM1L/AP2A1/NFE2L1/SERPINA12/INSIG1/PPP1CA/MST1/PDP2/FABP5/BRCA1/SLC25A33/PPARA/NUP93/ADIPOR2/KAT2A/CLYBL/PRKAA1/PSEN1/DNAJC15/NUP205/PID1/CYP27B1/PSMC1/BAD/TREM2/PSMD8/RORA/SNAI1/PSMA2/NUP50/IFNG/PRKAG1/OGT/NR4A3/ATP7A/PDP1/PPP1CB/PSMC5/ESRRB/PSMC2/ZBTB20/CDA/PSMB2/PSMD4/VCP/MTOR/MBTPS2/ME2/RHOA/TAZ/APP/SNCA/ELOVL6/ABCD1/ATCAY/CD244/MBTPS1/KPNB1/GCG/PDPR/PSMD1/PSMB4/ADCYAP1R1/NR1H4/SESN2/PSMD9/C1QTNF3/WDR5/P2RY1/PSMD3/POM121C/FAM3A/AAAS/NTSR1/NKX1-1	238
BP	GO:0044282	small molecule catabolic process	231/7096	445/18670	1.164e-09	4.417e-07	3.293e-07	TYMP/PNP/HK3/ASRGL1/HEXB/QPRT/ATP2B4/ALDH3A2/UPP1/HADHB/ENOSF1/PGK1/HIBADH/CYP27A1/ARG2/PFKM/PFKP/GAPDH/IL4I1/PPARD/CHP1/PCYOX1/HADH/GALM/HMGCL/GNPDA1/ACAA1/ALDH1A1/NPL/AHCY/CD44/CRYL1/ALDH7A1/ADH5/PHYH/PHYKPL/GK/SCARB1/BCKDK/GALE/FUT4/ALDH6A1/SLC9A1/PCBD1/SCP2/HAL/DDAH2/AKR1C3/HNMT/INPP1/APOE/HEXA/FUT7/FAH/ENTPD1/PGAM1/LRP5/PKM/ETFA/GALK1/RPE/TPI1/CPT2/HDDC3/TGFB1/ESD/NUDT1/AUH/ABCD3/PCK2/NAGK/NT5C/LEP/SYNJ1/PNKD/AKR1A1/DHDH/ECH1/ACADM/DBT/HYAL2/ALDOC/ACADS/CDADC1/DECR1/RENBP/ENO1/MTRR/IDO1/DPYD/ALDOA/GSTZ1/MCEE/AIG1/PLA2G15/ALDH2/ACOX1/ETFDH/ECI2/SLC27A2/HSD17B4/QDPR/ACACB/OGDH/HAGH/ACOX2/ALDH4A1/SYNJ2/BDH1/NUDT9/ACBD5/GPI/APOBEC3G/ACADSB/GLUD1/IDUA/PCYOX1L/OCRL/IRS2/BDH2/DAO/ADHFE1/ABHD3/DECR2/APOBEC3C/ALDH5A1/MLYCD/MCCC1/KYNU/HAAO/GUSB/OXCT1/SLC25A12/APOBEC2/PGM2/SHMT2/GLUD2/TST/PCCB/NUDT3/KHK/CBR3/ECI1/GK5/MPST/HSD17B10/INPP5K/IMPA2/CYP26B1/ALDH8A1/CTH/NUDT19/DERA/NUDT5/ETFB/PEX13/TYSND1/MTMR2/PPAT/CPT1A/EHHADH/FUT6/GALT/FOXK2/HYAL3/SORD/ACADVL/GLS/GOT2/ADPRM/PFKFB2/ADA/HADHA/AKR1B10/AGXT2/SHMT1/CEMIP/NUDT7/PPARA/ACAA2/SRD5A3/IDO2/AMT/APOBEC3B/ENO2/CYP27B1/ACOX3/BAD/BCKDHB/AMDHD1/STAB2/PGD/BCAT2/SULT1B1/ALDH1L1/CYP26A1/BCKDHA/CROT/CDA/ADPGK/LYVE1/MTOR/NT5C3A/ENPP4/NT5M/HYKK/UPP2/CYP4F3/ABCD1/ABHD16A/GLYCTK/ADAL/HMGCLL1/ABHD10/NUDT16/PFKL/CYP46A1/FGF23/HACL1/ADH7/TDO2/SESN2/MAT1A/NTSR1/HAO1/SNX17/INPP5A/ACOT8/IMPA1/PIPOX/RBKS	231
BP	GO:0019882	antigen processing and presentation	130/7096	226/18670	1.784e-09	6.397e-07	4.769e-07	FCGR1B/NOD2/LILRB2/FCGR1A/SLC11A1/CTSF/CTSD/PSMB9/ITGB5/KLC1/PSMB8/CD1C/AP1B1/TAP2/DYNC1LI1/CTSS/FGL2/TAP1/LGMN/SEC22B/CD1E/BCAP31/PSMA5/HFE/PSMD11/CD74/PDIA3/PSME1/KIF3B/OSBPL1A/KIFAP3/SAR1B/PSMB10/CD36/CAPZA2/DYNLL2/PSMA1/PSMA4/NCF4/HLA-F/TRAF6/NCF2/CENPE/IKBKG/NCF1/HLA-DPB1/HLA-DPA1/HLA-E/HLA-B/CD209/VAMP3/RELB/PSMB1/PSMC4/CD1B/CAPZA1/KIF4A/HLA-DMB/PSMD13/PSMB3/HLA-DOB/HLA-G/KIF2A/TAPBPL/HLA-DRA/AP1M2/RAB32/TAPBP/HLA-DMA/HLA-C/PSMB5/PSMD6/ARF1/PSMC3/AP2A2/PSME3/DNM2/PSMC6/DCTN2/LAG3/AP2S1/CD1D/CD1A/CTSV/CYBA/CYBB/CTSE/CANX/AP2A1/CALR/RAB8B/AP1S3/AP3B1/AP1G1/HLA-DQB2/RAB35/PSMC1/KIF2C/TREM2/ERAP1/PSMD8/HLA-A/PSMA2/AP1M1/RAB3B/ERAP2/SPTBN2/PSMC5/DYNC1LI2/KLC2/PSMC2/AP2M1/PSMB2/PSMD4/RAB33A/CCL19/CHUK/DCTN6/CD8A/PSMD1/CCR7/WAS/PSMB4/DCTN5/SEC24A/RAB27A/PSMD9/PSMD3/HLA-DOA/RFTN1	130
BP	GO:1903039	positive regulation of leukocyte cell-cell adhesion	126/7096	218/18670	2.097e-09	7.122e-07	5.31e-07	IGF1/NOD2/PNP/CCR2/FYN/NFKBIZ/PTPN6/LILRB2/ANXA1/BCL10/LYN/CD55/CSK/EGR3/TNFRSF14/BCL6/NLRP3/DUSP10/CD44/IL4R/CBFB/MAP3K8/PTPRC/IL15/ADAM8/TNF/CD74/LILRB1/DPP4/IL7R/RELA/DOCK8/TGFB1/CCDC88B/PTAFR/PAK1/SOCS5/LEP/TNFSF13B/FAM49B/CORO1A/LILRB4/TRAF6/ZBTB1/ITGA4/ZBTB7B/HLA-DPB1/HLA-DPA1/HLA-E/NCK1/CD209/NFKBID/PAK2/IL1B/AIF1/SIRPB1/AGER/CCL5/RASGRP1/RASAL3/PIK3R6/HLA-DMB/ICOSLG/HMGB1/EFNB1/IGFBP2/IL7/IL6ST/TESPA1/HLA-G/RAC1/IL6/LCK/CYLD/FLOT2/CTLA4/ETS1/VNN1/PDCD1LG2/CD47/LGALS1/CD1D/IL12RB1/GRB2/CD274/LGALS9/NFAT5/EBI3/ICOS/BTN2A2/HES1/ADA/HLX/VAV1/IL18/FADD/AP3B1/CD276/TFRC/TNFSF4/SART1/SOCS1/SIRPG/BAD/HAVCR2/IFNG/SKAP1/SPTA1/NR4A3/CD5/CD4/TNFRSF13C/IL12B/PRKCZ/CD80/PRKCQ/RHOA/CD83/CCL19/MALT1/ZBTB16/CCR7/CD3E/PDCD1/CD24/IL23A	126
BP	GO:0002821	positive regulation of adaptive immune response	70/7096	105/18670	2.358e-09	7.608e-07	5.672e-07	CCR2/NFKBIZ/IL27RA/ANXA1/STX7/MAD2L2/SLC11A1/STAT6/NLRP3/CD40/CD1C/PTPRC/P2RX7/CD1E/TNF/CD226/TGFB1/IL18R1/SOCS5/TNFSF13B/FAM49B/HLA-F/TRAF6/ZBTB1/HLA-E/HLA-B/RSAD2/NFKBID/IL1B/FBXO38/CD1B/SIRT1/IL6ST/IL1R1/HLA-G/IL6/HLA-C/FCER2/MLH1/CLCF1/PVR/CD1D/IL12RB1/CD1A/CD274/FZD5/ADA/HLX/IL18/FADD/TRAF2/TFRC/TNFSF4/HLA-A/SKAP1/EXOSC3/CD4/TNFRSF13C/IL12B/EIF2AK4/PRKCZ/CD80/TBX21/PRKCQ/EXOSC6/CCL19/MALT1/PAXIP1/ATAD5/IL23A	70
BP	GO:0009615	response to virus	176/7096	326/18670	2.596e-09	7.611e-07	5.674e-07	RNASE2/STMN1/ATG7/IRF7/PARP9/IRF1/DDX21/AZU1/GBP1/PLSCR1/NPC2/NLRP3/BATF3/FLNA/PMAIP1/TNFAIP3/NLRC5/CD40/BIRC2/FGL2/STAT1/CXCL9/OASL/PTPRC/IL15/IFNAR1/IFITM2/TNF/SLFN11/IFITM1/DDX60/IRAK3/CXCL10/SKP2/ERCC6/IFITM3/LILRB1/AIM2/CXCL12/TICAM1/RELA/IFNGR2/MX2/ELMOD2/EXOC1/SIN3A/XPR1/TRIM22/IRF9/HSPB1/IFIT3/ISG20/HYAL2/IKBKG/AIMP1/TSPAN32/DDX58/ADARB1/FGR/TRAF3/OAS3/IFI27/RSAD2/ENO1/IL1B/ODC1/IFIT2/RNASE6/HMGA1/SAMHD1/CCL5/DHX9/ACTA2/MMP12/PML/OAS2/ISG15/IFI44/CLU/TRIM11/HNRNPUL1/NLRP9/APOBEC3G/SLFN13/MAVS/IFI44L/IL6/APOBEC3C/IFIT5/LSM14A/PUM2/DDX3X/ILF3/ARF1/BANF1/DTX3L/ZC3HAV1/BCL2L11/NPLOC4/IFIH1/SEC14L1/SERINC3/CCDC130/IVNS1ABP/TARBP2/BCL2/CCL8/ANKRD17/BIRC3/UNC13D/CFL1/MX1/DDX1/ZMYND11/IFNK/RNASEL/HTRA1/IL12RB1/PCBP2/GTF2F1/LGALS9/IFIT1/HYAL3/DDIT4/IRF2/ZMPSTE24/CHRM2/LAMTOR5/DMBT1/RTP4/IFNGR1/EIF2AK2/C1QBP/CNOT7/MUL1/FADD/GPATCH3/PRF1/POLR3E/TNFSF4/TLR8/RIOK3/FMR1/APOBEC3B/HERC5/BAD/FOSL1/PSMA2/IFNG/MAPK11/TRIM15/NLRX1/TLR3/IFNAR2/IL12B/TRAF3IP1/TRIM6/EIF2AK4/MICA/TBX21/POLR3F/NT5C3A/PIM2/UNC93B1/RNF216/TSPAN6/CCL19/ADAR/CHUK/CCL4/ZCCHC3/IL23A/POLR3K/EXOSC5/BTBD17/MIR146A	176
BP	GO:0050852	T cell receptor signaling pathway	118/7096	202/18670	2.831e-09	7.611e-07	5.674e-07	FYN/EZR/KCNN4/NFKBIZ/PTPN6/BCL10/CSK/GBP1/PTPN2/PSMB9/CUL1/PSMB8/BTN2A1/PTPRC/UBE2N/PSMA5/PSMD11/TNFRSF21/NFKB1/PSME1/DUSP3/LCP2/RELA/DENND1B/CD226/PAK1/PSMB10/PSMA1/PSMA4/LILRB4/TRAF6/IKBKG/EIF2B5/PTPN22/HLA-DPB1/HLA-DPA1/NCK1/PDE4B/HRAS/ABL1/NFKBID/PSMB1/PAK2/PSMC4/THEMIS2/CD3D/PLCG2/PSMD13/ICOSLG/TRAC/PSMB3/RBCK1/TESPA1/RAB29/ELF1/TRBC1/ITK/LCK/HLA-DRA/CYLD/CTLA4/PSMB5/PSMD6/BTN3A2/PSMC3/TRAT1/PSME3/PRKD2/CD247/PSMC6/PIK3CD/TEC/BTN3A3/CD3G/CD300A/BTN2A2/ADA/THEMIS/CD276/PSEN1/BTN3A1/MAPK1/HLA-DQB2/PAG1/PSMC1/PRAM1/EIF2B1/PSMD8/PSMA2/SKAP1/TXK/CD4/EIF2B3/CACNB3/PSMC5/PSMC2/PSMB2/PSMD4/PRKCQ/LIME1/MALT1/CHUK/PSMD1/CCR7/WAS/EIF2B2/CD3E/PSMB4/CACNA1F/PSMD9/UBASH3A/MOG/PSMD3/LAT/PIK3CB/PTPRJ/RFTN1/PHPT1	118
BP	GO:0030217	T cell differentiation	136/7096	240/18670	2.916e-09	7.611e-07	5.674e-07	PNP/CCR2/PTGER4/NFKBIZ/LILRB2/ANXA1/IRF1/TSC1/SOD1/CLEC4D/JMJD6/EGR3/STAT6/STAT3/PTPN2/SOX13/BCL6/NLRP3/CLEC4E/SH3RF1/SMAD7/SLC46A2/DUSP10/CD2/LFNG/FGL2/LY9/IL4R/CBFB/PTPRC/IL15/EGR1/ADAM8/BATF/CD74/PRELID1/FUT7/IL7R/TGFB1/PPP3CB/IL18R1/SOCS5/LEP/SRF/METTL3/LILRB4/ZBTB1/TCIRG1/SEMA4A/PTPN22/ZBTB7B/DTX1/RELB/ABL1/RSAD2/NFKBID/CD3D/RASGRP1/CLPTM1/PIK3R6/HMGB1/IL7/TNFRSF18/TESPA1/HLA-G/ITK/IL6/LCK/CYLD/CR1/CTLA4/PRR7/PATZ1/VNN1/NRARP/BCL2/BMP4/CYP26B1/NFATC2/PIK3CD/CCR6/LAG3/GPR18/CD3G/CD1D/IL12RB1/LGALS9/LIG4/BTN2A2/FZD5/ADA/HLX/RHOH/THEMIS/VAV1/IL18/FADD/AP3B1/ADAM17/BCL11B/PREX1/TNFSF4/WNT1/SART1/KAT2A/SOCS1/BAD/ZFP36L2/RORA/IFNG/ATP7A/FANCD2/CD4/FZD7/IL12B/DROSHA/PRKCZ/CD80/TBX21/MTOR/FOXP1/RHOA/GPR183/FOXN1/FANCA/CD83/SOX4/CCL19/MALT1/ZBTB16/CD8A/CCR7/TNFSF8/CD3E/IL23A/HLA-DOA	136
BP	GO:0006914	autophagy	252/7096	496/18670	2.948e-09	7.611e-07	5.674e-07	SRPX/S100A9/S100A8/ATP6V0D2/HTR2B/ATG4C/BMF/STAM/NAMPT/ATG7/PINK1/CTSA/ATG3/MAP1S/TSC1/MCOLN1/DRAM2/C9orf72/STAT3/TPCN1/TMBIM6/GNAI3/GAPDH/RNF41/ATP6V1C1/CISD2/FEZ2/ULK2/FBXW7/DHRSX/ATG14/UCHL1/SEC22B/SQSTM1/WDR81/LAMP2/CTSK/LAMP3/PSAP/HMOX1/ATP6V0C/NUPR1/TRIM13/VPS37B/ERCC4/GSK3B/PLAA/VPS13A/TICAM1/TBC1D5/VPS41/CHMP4B/SH3BP4/CSNK2A2/CDC37/WDR24/EXOC1/ITPR1/ARSB/RAB23/HGF/FIS1/HIF1A/MAP1LC3A/TRIM22/HSPB1/DYNLL2/ATG101/LEP/ZKSCAN3/TAB3/RAB24/TFEB/IKBKG/TCIRG1/MCL1/HTRA2/PTPN22/TP53INP2/QSOX1/UBXN2B/TMEM41B/SPTLC2/CDK5/PLK2/CASP3/KLHL22/ABL1/ATP6V1A/TEX264/RAB3GAP1/LAMTOR1/CLN3/NSFL1C/VPS33A/VPS37C/VTA1/KAT8/DAPK1/RRAGD/CSNK2B/ATG13/HMGB1/WIPI1/NPRL3/RAB8A/CLU/SIRT1/ACBD5/RGS19/RAB33B/GPSM1/PLEKHM1/ATP6V1B2/MLST8/LRRK2/EIF4G2/PPARGC1A/MAP1LC3C/FLCN/ATP6V1D/PTK2/ATM/SNX6/ATG9A/HDAC10/WDR6/PHF23/PRKAG2/BCL2L11/ZFYVE1/PLK3/TBC1D17/KAT5/VPS13D/LAMTOR4/MAPK8/EPM2A/TRIM21/UBQLN2/MEFV/VPS18/BCL2/VPS51/EI24/ATG4B/NEDD4/ATP6V0E2/CHMP2A/TOMM22/RAB39B/PACS2/MARK2/MFSD8/TSG101/TOLLIP/PRKACA/RAB5A/ADRB2/ATG2B/HGS/WDR45B/TOMM40/FOXK2/USP30/VTI1A/SREBF2/VPS4B/FZD5/ATP6V1G2/CPTP/RRAGA/ZMPSTE24/STUB1/DNM1L/TOMM20/VDAC1/EEF1A2/LAMTOR5/VPS25/IRF8/ULK1/MUL1/USP10/YOD1/ABL2/MID2/SESN1/PRKAA1/PSEN1/MTMR3/SNX5/STX12/SH3GLB1/IFT20/SMCR8/NPRL2/FBXL2/BAD/EIF4G1/TREM2/DAP/CD84/EXOC4/ATG16L2/EVA1A/IFNG/PRKAG1/TRIM65/MTMR9/DAPL1/TOMM5/GABARAPL1/RNF185/SCFD1/CLEC16A/RNF5/LACRT/ATG4D/ATG4A/VPS16/OPTN/MTDH/EIF2AK4/VPS26B/SNAP29/TRAPPC8/VCP/MTOR/SBF2/PIM2/ERN1/DAPK2/SNCA/ATP6V1B1/MET/NRBF2/NBR1/DRAM1/LZTS1/HMGB4/SESN2/SLC38A9/CAPNS1/SUPT20H/FOXO3/SNX32/PIK3CB/ATG12/PRKAB1/KDM4A/FUNDC1	252
BP	GO:0061919	process utilizing autophagic mechanism	252/7096	496/18670	2.948e-09	7.611e-07	5.674e-07	SRPX/S100A9/S100A8/ATP6V0D2/HTR2B/ATG4C/BMF/STAM/NAMPT/ATG7/PINK1/CTSA/ATG3/MAP1S/TSC1/MCOLN1/DRAM2/C9orf72/STAT3/TPCN1/TMBIM6/GNAI3/GAPDH/RNF41/ATP6V1C1/CISD2/FEZ2/ULK2/FBXW7/DHRSX/ATG14/UCHL1/SEC22B/SQSTM1/WDR81/LAMP2/CTSK/LAMP3/PSAP/HMOX1/ATP6V0C/NUPR1/TRIM13/VPS37B/ERCC4/GSK3B/PLAA/VPS13A/TICAM1/TBC1D5/VPS41/CHMP4B/SH3BP4/CSNK2A2/CDC37/WDR24/EXOC1/ITPR1/ARSB/RAB23/HGF/FIS1/HIF1A/MAP1LC3A/TRIM22/HSPB1/DYNLL2/ATG101/LEP/ZKSCAN3/TAB3/RAB24/TFEB/IKBKG/TCIRG1/MCL1/HTRA2/PTPN22/TP53INP2/QSOX1/UBXN2B/TMEM41B/SPTLC2/CDK5/PLK2/CASP3/KLHL22/ABL1/ATP6V1A/TEX264/RAB3GAP1/LAMTOR1/CLN3/NSFL1C/VPS33A/VPS37C/VTA1/KAT8/DAPK1/RRAGD/CSNK2B/ATG13/HMGB1/WIPI1/NPRL3/RAB8A/CLU/SIRT1/ACBD5/RGS19/RAB33B/GPSM1/PLEKHM1/ATP6V1B2/MLST8/LRRK2/EIF4G2/PPARGC1A/MAP1LC3C/FLCN/ATP6V1D/PTK2/ATM/SNX6/ATG9A/HDAC10/WDR6/PHF23/PRKAG2/BCL2L11/ZFYVE1/PLK3/TBC1D17/KAT5/VPS13D/LAMTOR4/MAPK8/EPM2A/TRIM21/UBQLN2/MEFV/VPS18/BCL2/VPS51/EI24/ATG4B/NEDD4/ATP6V0E2/CHMP2A/TOMM22/RAB39B/PACS2/MARK2/MFSD8/TSG101/TOLLIP/PRKACA/RAB5A/ADRB2/ATG2B/HGS/WDR45B/TOMM40/FOXK2/USP30/VTI1A/SREBF2/VPS4B/FZD5/ATP6V1G2/CPTP/RRAGA/ZMPSTE24/STUB1/DNM1L/TOMM20/VDAC1/EEF1A2/LAMTOR5/VPS25/IRF8/ULK1/MUL1/USP10/YOD1/ABL2/MID2/SESN1/PRKAA1/PSEN1/MTMR3/SNX5/STX12/SH3GLB1/IFT20/SMCR8/NPRL2/FBXL2/BAD/EIF4G1/TREM2/DAP/CD84/EXOC4/ATG16L2/EVA1A/IFNG/PRKAG1/TRIM65/MTMR9/DAPL1/TOMM5/GABARAPL1/RNF185/SCFD1/CLEC16A/RNF5/LACRT/ATG4D/ATG4A/VPS16/OPTN/MTDH/EIF2AK4/VPS26B/SNAP29/TRAPPC8/VCP/MTOR/SBF2/PIM2/ERN1/DAPK2/SNCA/ATP6V1B1/MET/NRBF2/NBR1/DRAM1/LZTS1/HMGB4/SESN2/SLC38A9/CAPNS1/SUPT20H/FOXO3/SNX32/PIK3CB/ATG12/PRKAB1/KDM4A/FUNDC1	252
BP	GO:1904951	positive regulation of establishment of protein localization	234/7096	456/18670	3.49e-09	8.663e-07	6.459e-07	IGF1/ITGAM/HTR2B/NOD2/CLEC5A/FYN/TLR1/EZR/TLR2/KCNN4/PTGER4/RAC2/ARF6/PINK1/WNT5A/CD58/IL17RA/OAZ2/FCN1/PTGS2/LILRA5/GAPDH/TNFRSF14/NLRP3/CLEC4E/PPARD/CHP1/HPS4/FLNA/PMAIP1/MBP/MIF/CIB1/CD2/WLS/FBXW7/YWHAH/LILRA2/IL4R/NLRP12/RGCC/JAK2/P2RX7/BCAP31/ADAM8/TNF/C2CD5/IL1RAP/RAN/GSK3B/AIM2/EDEM1/HCLS1/TRIM16/CSNK2A2/TGFB1/PPP3CB/EXOC1/MIEF1/AACS/UNC13B/FIS1/ARRB1/HIF1A/SAR1B/FFAR2/PAK1/FRMD8/PCM1/PANX1/LEP/PRKCD/UBE2D3/CEP131/HYAL2/MCU/HTRA2/TLR4/DDX58/PTPN22/FGR/HLA-E/CDK5/SFN/HRAS/ABL1/CASP8/EMD/ZPR1/IL1B/AIF1/AGER/CNST/UBR5/RASGRP1/DHX9/C2CD2L/MMP12/MPC2/ATG13/LRP1/HMGB1/TRPM4/DOC2B/GPI/RAC1/GLUD1/RAB29/SPTBN1/MAVS/IL6/IRS2/EDEM2/LRRK2/MYO1C/RHOU/PDCD5/GLMN/SERP1/SRI/SAR1A/ARF1/OXCT1/ALOX15B/ARIH2/PLK3/IFIH1/MAPK8/ABLIM3/RPH3AL/GOLPH3L/BCL2/GPR27/BCAS3/MICALL2/GZMB/TSG101/ABCG1/KIF20B/PRKACA/IL1A/CASP1/SYTL4/OSM/UBL4B/CD274/PDX1/LGALS9/TM7SF3/YWHAQ/SREBF2/FZD5/CD2AP/CCT4/PFKFB2/F2R/DNM1L/HSPA1L/CRTAM/CCT8/CEMIP/IFNGR1/EGFR/ADAM9/TNFSF4/RIOK2/GIPR/PRKAA1/PSEN1/TLR8/MDM2/MAPK1/TCF7L2/SH3GLB1/YWHAE/BAD/TREM2/PLA2G6/TNFRSF4/FRMD4A/UBL5/TGFB3/NLRP1/HAVCR2/TSLP/RUFY3/IFNG/PPP1R13B/MAPK11/BAP1/CHP2/KIF5B/B3GAT3/TMEM30A/CD34/CACNB3/NLRP2/YWHAG/TRIM6/CD33/PRKCZ/CSF1R/CEP120/SCAMP5/TRPV4/ITGB1BP1/SOX4/PDCD10/CCL19/TM9SF4/CHUK/CD244/GCG/ICE1/XPO4/NLGN2/IL26/GJA1/SMO/SEC24A/HMGB4/IL17RB/NR1H4/TARDBP/UCN3/RBP4/PSMD9/C1QTNF3/IL17RC/CTDSPL2/GHRL/IGHD/SEC16B/PHPT1	234
BP	GO:0002699	positive regulation of immune effector process	124/7096	216/18670	4.951e-09	1.183e-06	8.823e-07	ITGAM/NOD2/CCR2/RAC2/NFKBIZ/ANXA1/STX7/APPL2/BCL10/LYN/MAD2L2/DDX21/WNT5A/STAT6/TNFRSF14/NLRP3/CD40/CD1C/MIF/IL4R/PTPRC/P2RX7/CD1E/LAMP1/TNF/DDX60/CD74/HMOX1/C12orf4/GPRC5B/LILRB1/TICAM1/CD226/TGFB1/STXBP1/IL18R1/PTAFR/FFAR2/SOCS5/CD36/STXBP2/FAM49B/HLA-F/TRAF6/ZBTB1/TLR4/DDX58/FGR/HLA-E/HLA-B/RSAD2/NFKBID/IL1B/FBXO38/RASGRP1/CD1B/RAP1A/HLA-DMB/IL1R1/GPI/HLA-G/MAVS/IL6/PUM2/HLA-C/RPS19/ADORA2B/FCER2/MLH1/ANKRD17/CLCF1/UNC13D/PVR/LAG3/DDX1/CD1D/IL12RB1/CD1A/CD300A/LGALS9/FER/RABGEF1/FZD5/HLX/ULBP2/CRTAM/VAV1/KIR2DL4/IL18/FADD/TRAF2/TFRC/TNFSF4/AP1G1/IL13RA2/TNFRSF4/CD84/HLA-A/IFNG/NCR3/NR4A3/EXOSC3/TRIM15/SNX4/LBP/IL12B/SH2D1A/TRIM6/MICA/PRKCZ/CD80/TBX21/IL18RAP/EXOSC6/CCL19/MALT1/CD244/FOXF1/PAXIP1/ATAD5/ZCCHC3/IL23A/RBP4/PTPRJ	124
BP	GO:0050870	positive regulation of T cell activation	117/7096	202/18670	6.567e-09	1.514e-06	1.128e-06	IGF1/NOD2/PNP/CCR2/FYN/NFKBIZ/PTPN6/LILRB2/ANXA1/BCL10/LYN/CD55/CSK/EGR3/TNFRSF14/BCL6/NLRP3/DUSP10/IL4R/CBFB/MAP3K8/PTPRC/IL15/ADAM8/CD74/LILRB1/DPP4/IL7R/DOCK8/TGFB1/CCDC88B/PAK1/SOCS5/LEP/TNFSF13B/FAM49B/CORO1A/LILRB4/TRAF6/ZBTB1/ZBTB7B/HLA-DPB1/HLA-DPA1/HLA-E/NCK1/CD209/NFKBID/PAK2/IL1B/AIF1/SIRPB1/AGER/CCL5/RASGRP1/RASAL3/PIK3R6/HLA-DMB/ICOSLG/HMGB1/EFNB1/IGFBP2/IL7/IL6ST/TESPA1/HLA-G/RAC1/IL6/LCK/CYLD/FLOT2/CTLA4/VNN1/PDCD1LG2/CD47/LGALS1/CD1D/IL12RB1/GRB2/CD274/LGALS9/EBI3/ICOS/BTN2A2/HES1/ADA/HLX/VAV1/IL18/FADD/AP3B1/CD276/TFRC/TNFSF4/SART1/SOCS1/SIRPG/BAD/HAVCR2/IFNG/SPTA1/CD5/CD4/TNFRSF13C/IL12B/PRKCZ/CD80/PRKCQ/RHOA/CD83/CCL19/MALT1/ZBTB16/CCR7/CD3E/PDCD1/CD24/IL23A	117
BP	GO:0050863	regulation of T cell activation	169/7096	314/18670	7.187e-09	1.599e-06	1.192e-06	IGF1/NOD2/PNP/CCR2/FYN/RAC2/NFKBIZ/PTPN6/LILRB2/ANXA1/BCL10/LYN/CD55/IRF1/CSK/SOD1/ARG2/GPNMB/EGR3/PTPN2/SOX13/TNFRSF14/BCL6/NLRP3/SH3RF1/SMAD7/SLC46A2/DUSP10/CD2/FGL2/IL4R/CEBPB/CBFB/MAP3K8/PTPRC/IL15/HFE/ADAM8/CD74/TNFRSF21/PRELID1/LILRB1/DPP4/DUSP3/IL7R/DOCK8/TGFB1/CCDC88B/PAK1/SOCS5/LEP/TNFSF13B/METTL3/FAM49B/CORO1A/LILRB4/TRAF6/ZBTB1/CLC/IL20RB/PTPN22/ZBTB7B/SOCS6/HLA-DPB1/HLA-DPA1/HLA-E/NCK1/DTX1/CD209/CASP3/ABL1/IDO1/NFKBID/PAK2/IL1B/AIF1/SIRPB1/AGER/CCL5/RASGRP1/RASAL3/CLPTM1/PIK3R6/HLA-DMB/ICOSLG/HMGB1/EFNB1/IGFBP2/IL7/TNFRSF18/IL6ST/TESPA1/HLA-G/RAC1/IL6/LCK/CYLD/CR1/FLOT2/CTLA4/GLMN/TIGIT/VSIG4/SCGB1A1/VNN1/PDCD1LG2/NRARP/BMP4/CYP26B1/NFATC2/CD47/LGALS1/LAG3/CD1D/IL12RB1/GRB2/CD300A/CD274/LGALS9/LAX1/EBI3/ICOS/BTN2A2/HES1/ADA/HLX/VAV1/IL18/FADD/AP3B1/CD276/TFRC/TNFSF4/SART1/KAT2A/PAG1/SOCS1/SIRPG/BAD/HAVCR2/IFNG/SPTA1/CD5/TNFSF18/FANCD2/CD4/TNFRSF13C/IL12B/DROSHA/PRKCZ/CD80/TBX21/PRKCQ/RHOA/FOXN1/FANCA/CD83/CCL19/MALT1/ZBTB16/CCR7/TNFSF8/CD3E/PDCD1/TWSG1/CD24/IL23A/HLA-DOA/LAT	169
BP	GO:0019884	antigen processing and presentation of exogenous antigen	107/7096	182/18670	9.404e-09	2.023e-06	1.508e-06	FCGR1B/FCGR1A/CTSF/CTSD/PSMB9/ITGB5/KLC1/PSMB8/CD1C/AP1B1/TAP2/DYNC1LI1/CTSS/TAP1/LGMN/SEC22B/CD1E/PSMA5/PSMD11/CD74/PDIA3/PSME1/KIF3B/OSBPL1A/KIFAP3/SAR1B/PSMB10/CD36/CAPZA2/DYNLL2/PSMA1/PSMA4/NCF4/HLA-F/TRAF6/NCF2/CENPE/IKBKG/NCF1/HLA-DPB1/HLA-DPA1/HLA-E/HLA-B/VAMP3/PSMB1/PSMC4/CD1B/CAPZA1/KIF4A/HLA-DMB/PSMD13/PSMB3/HLA-DOB/HLA-G/KIF2A/HLA-DRA/AP1M2/TAPBP/HLA-DMA/HLA-C/PSMB5/PSMD6/ARF1/PSMC3/AP2A2/PSME3/DNM2/PSMC6/DCTN2/LAG3/AP2S1/CD1D/CD1A/CTSV/CYBA/CYBB/CTSE/CANX/AP2A1/CALR/AP1S3/AP3B1/AP1G1/HLA-DQB2/PSMC1/KIF2C/PSMD8/HLA-A/PSMA2/AP1M1/SPTBN2/PSMC5/DYNC1LI2/KLC2/PSMC2/AP2M1/PSMB2/PSMD4/CHUK/DCTN6/PSMD1/PSMB4/DCTN5/SEC24A/PSMD9/PSMD3/HLA-DOA	107
BP	GO:0016052	carbohydrate catabolic process	115/7096	199/18670	1.054e-08	2.194e-06	1.636e-06	IGF1/CBFA2T3/HK3/HEXB/LDHA/FBP1/ENOSF1/PGK1/MANBA/MGAM/STAT3/PFKFB3/NUP62/NUP160/PFKM/GM2A/PFKP/GAPDH/GALM/ALDH1A1/NUP214/CRYL1/GK/SLC2A6/GALE/P2RX7/FUT4/NUPR1/AGL/FUT7/PGAM1/LRP5/PKM/GALK1/RPE/EIF6/TPI1/ZBTB7A/NUP85/HIF1A/SEH1L/MAN2B1/AKR1A1/DHDH/INSR/PPP1R3D/ALDOC/NUP43/ENO1/ALDOA/POM121/OGDH/PHKB/GPI/PFKFB4/PPARGC1A/CTBS/PHKG1/DHTKD1/GUSB/SLC25A12/PGM2/PRKAG2/MYOG/NCOR1/KHK/PFKFB1/GK5/NUP88/HDAC4/PPP1R3B/DERA/NUDT5/NAGA/NUP107/FUT6/GALT/FOXK2/SORD/DDIT4/PGK2/PFKFB2/ARNT/PPP1CA/PPARA/NUP93/PRKAA1/PSEN1/NUP205/ENO2/BAD/SLC4A1/GAA/NUP50/IFNG/PYGM/PRKAG1/OGT/NEU1/PGD/PPP1CB/PYGL/ESRRB/ZBTB20/ADPGK/APP/GLYCTK/MAN2B2/ABHD10/PFKL/TREH/G6PC/POM121C/AAAS/RBKS	115
BP	GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	66/7096	100/18670	1.243e-08	2.507e-06	1.869e-06	CCR2/NFKBIZ/IL27RA/ANXA1/STX7/MAD2L2/SLC11A1/STAT6/NLRP3/CD40/CD1C/PTPRC/P2RX7/CD1E/TNF/CD226/TGFB1/IL18R1/SOCS5/TNFSF13B/FAM49B/HLA-F/TRAF6/ZBTB1/HLA-E/HLA-B/RSAD2/NFKBID/IL1B/FBXO38/CD1B/IL1R1/HLA-G/IL6/HLA-C/FCER2/MLH1/CLCF1/PVR/CD1D/IL12RB1/CD1A/CD274/FZD5/ADA/HLX/IL18/FADD/TRAF2/TFRC/TNFSF4/HLA-A/EXOSC3/CD4/TNFRSF13C/IL12B/PRKCZ/CD80/TBX21/PRKCQ/EXOSC6/CCL19/MALT1/PAXIP1/ATAD5/IL23A	66
BP	GO:0002819	regulation of adaptive immune response	96/7096	160/18670	1.287e-08	2.516e-06	1.876e-06	CCR2/NFKBIZ/PTPN6/IL27RA/ANXA1/STX7/MAD2L2/IRF7/SLC11A1/IRF1/STAT6/TNFRSF14/BCL6/NLRP3/SMAD7/DUSP10/TNFAIP3/CD40/CD1C/IL4R/PTPRC/P2RX7/CD1E/HFE/TNF/LILRB1/IL7R/CD226/TGFB1/PPP3CB/IL18R1/SOCS5/TNFSF13B/FAM49B/HLA-F/TRAF6/ZBTB1/CLC/IL20RB/ZBTB7B/HLA-E/HLA-B/RSAD2/NFKBID/IL1B/FBXO38/AGER/CD1B/HMGB1/SIRT1/TRPM4/IL6ST/IL1R1/HLA-G/ADCY7/IL6/CR1/HLA-C/FCER2/MLH1/PARP3/CLCF1/PVR/CD1D/IL12RB1/CD1A/CD274/FZD5/ADA/HLX/IL18/FADD/TRAF2/TFRC/TNFSF4/HLA-A/HAVCR2/SKAP1/EXOSC3/CD4/TNFRSF13C/IL12B/EIF2AK4/PRKCZ/CD80/TBX21/PRKCQ/APLF/EXOSC6/CCL19/MALT1/WAS/PAXIP1/ATAD5/IL23A/MEF2C	96
BP	GO:0043900	regulation of multi-organism process	209/7096	405/18670	1.326e-08	2.518e-06	1.877e-06	IGF1/TRIM32/CLEC7A/GRN/CD55/ZFP36/PARP9/ARG2/SYT11/FCN1/PLSCR1/GAPDH/TNFAIP3/MIF/BIRC2/CIB1/FGL2/LY96/LY86/STAT1/LILRA2/AGO2/OASL/IL15/LAMP3/IFITM2/P2RX7/TNF/IFITM1/DDX60/CD74/CHD1/ERCC6/TRIM13/VPS37B/IFITM3/APOE/LILRB1/AIM2/CHMP4B/ELMOD2/STXBP1/SIN3A/UNC13B/PTAFR/MORC2/CD36/ISG20/STAU1/TRAF6/PTX3/MAPKBP1/TRIM26/TSPAN32/DDB1/TFAP4/DDX58/ADARB1/TRAF3/OAS3/IFI27/ARHGDIB/CACTIN/IGF2R/RSAD2/TAF11/IL1B/CCL5/DHX9/GTF2F2/SRPK2/MMP12/PLB1/MDFIC/PML/POLR2L/ISG15/VAPB/TRIM11/APOBEC3G/MAVS/SIGLEC16/CTDP1/ACVR1B/CDK9/APOBEC3C/SPINK1/IFIT5/POLR2H/PUM2/DDX3X/ILF3/BANF1/DTX3L/ZC3HAV1/PSMC3/CCDC87/HDAC2/BCL2L11/NPLOC4/SEC14L1/TRIM21/FCER2/TARBP2/BCL2/CCL8/TBC1D20/TNIP1/CHMP2A/ANKRD17/INPP5K/HDAC4/TIMP1/CCNK/SIGLEC11/BIRC3/TSG101/CFL1/MX1/TOP2B/LGALS1/FAM170B/SUPT4H1/SETDB1/PPP2R3C/INHBA/RNASEL/HTRA1/RSF1/IL12RB1/PCBP2/GTF2F1/HPGDS/LGALS9/CYBA/IFIT1/SRPK1/HYAL3/VPS4B/PGLYRP4/POLR2F/ZMPSTE24/ADA/POLR2D/CALR/PLCB1/EIF2AK2/C1QBP/CNOT7/MUL1/PKN2/GPATCH3/MID2/PRF1/ANXA2P2/POLR2K/RIOK3/FMR1/HERC5/SIGIRR/FBXL2/BAD/SMC3/FUCA2/HAVCR2/NELFCD/IFNG/VIP/LHFPL2/TRIM15/CD4/NLRX1/LACRT/IL12B/OPTN/TRAF3IP1/TRIM6/EIF2AK4/PC/CSF1R/ANXA2/FOXP1/HPN/CCNT1/AURKA/CX3CL1/B4GALT1/RNF216/TSPAN6/ADAR/CCL4/PPIB/POLR2I/ZCCHC3/SYDE1/CACNA1H/NUCKS1/TARDBP/PRKCA/IL23A/P2RY1/FAM3A/TOP2A/APCS/CXCL6/EXOC2/POMZP3/BTBD17/SASH1	209
BP	GO:2001233	regulation of apoptotic signaling pathway	209/7096	406/18670	1.714e-08	3.16e-06	2.356e-06	SRPX/IGF1/S100A9/S100A8/ITPRIP/FYN/PEA15/BMF/TRIM32/CX3CR1/CDKN2D/SKIL/BCL10/NR4A2/PINK1/GCLM/LMNA/SOD1/SLC35F6/ERP29/PTPN2/TMBIM6/GNAI3/PTGS2/TNFRSF10A/SH3RF1/STRADB/PMAIP1/EYA3/TNFAIP3/BCL2A1/MIF/SIAH1/FBXW7/CTSC/YWHAH/ACKR3/CD44/JAK2/GSTP1/PTPRC/FAS/MAGED1/BCAP31/TNF/CD74/HMOX1/PTPMT1/NUPR1/PDIA3/TMEM14A/GSK3B/PRELID1/CXCL12/TMC8/RELA/CSNK2A2/HIGD1A/HGF/FIS1/HIF1A/CTNNA1/WFS1/HSPB1/MAPK7/FEM1B/PCGF2/PRKCD/PTTG1IP/HNRNPK/MNT/HYAL2/TMEM161A/NDUFS3/TFAP4/MCL1/MPV17L/HTRA2/FZD9/TPD52L1/NCK1/TNFRSF12A/SFN/SP100/ENO1/TNFSF10/GCLC/CASP8/PAK2/IL1B/DEDD2/ARHGEF2/PML/PHIP/CHCHD10/IL7/TRADD/CLU/RAF1/RBCK1/SIRT1/SFPQ/ELL3/LCK/G0S2/CYLD/SLC25A5/LRRK2/PLAUR/FLCN/PDCD5/DDX3X/PRR7/WWOX/MUC1/VNN1/BCL2L11/BMP5/TXNDC12/SERINC3/MAPK8/NRP1/PSME3/NACC2/IVNS1ABP/MMP9/TMEM102/BCL2/GNAI2/BMP4/BAX/SERPINE1/HMGB2/NOC2L/CRADD/CASP2/CTH/GZMB/SGMS1/IL1A/ZMYND11/INHBA/CREB3/MLLT11/PDX1/LGALS9/UNC5B/VDAC2/RFFL/YWHAQ/YBX3/TRAF1/DNM1L/CAAP1/NFE2L2/TNFRSF10B/PPP1CA/PPP2R1B/BRCA1/MUL1/FADD/RRM2B/COL2A1/TRAF2/ACAA2/ZC3HC1/DEPTOR/PSEN1/MDM2/TCF7L2/YWHAE/EYA4/TAF9B/BAD/PLA2G6/SNAI1/BCLAF1/ST18/RAD9A/PPP1R13B/FAIM2/MOAP1/DNAJA1/HYOU1/RET/ZSWIM2/MAZ/RB1/MAP2K5/DBH/WDR35/YWHAG/MSX1/TERT/GPX1/MEIS3/TRIAP1/DAPK2/CX3CL1/BAG5/BAK1/FAIM/BCL2L2/ATAD5/BMPR1B/SIAH2/FIGNL1/DDIAS/MAPK9	209
BP	GO:0002706	regulation of lymphocyte mediated immunity	90/7096	149/18670	2.306e-08	4.134e-06	3.082e-06	CCR2/PTPN6/IL27RA/SERPINB9/STX7/MAD2L2/STAT6/BCL6/NLRP3/SMAD7/CD40/CD1C/PTPRC/P2RX7/CD1E/HFE/LAMP1/TNF/LILRB1/IL7R/CD226/TGFB1/PPP3CB/IL18R1/LEP/FAM49B/HLA-F/TRAF6/ZBTB1/CLC/IL20RB/HLA-E/HLA-B/RSAD2/IL1B/CLEC12B/FBXO38/AGER/RASGRP1/CD1B/PIK3R6/HMGB1/CRK/TRPM4/IL1R1/HLA-G/IL6/CR1/HLA-C/CD96/FCER2/MLH1/PARP3/CLCF1/PVR/LAG3/CD1D/IL12RB1/CD1A/LGALS9/FZD5/ULBP2/CRTAM/VAV1/KIR2DL4/IL18/FADD/TRAF2/TFRC/TNFSF4/AP1G1/HLA-A/HAVCR2/NCR3/SERPINB4/EXOSC3/IL12B/SH2D1A/MICA/PRKCZ/TBX21/NCR1/IL18RAP/APLF/EXOSC6/MALT1/WAS/PAXIP1/ATAD5/IL23A	90
BP	GO:0050714	positive regulation of protein secretion	146/7096	268/18670	2.68e-08	4.59e-06	3.422e-06	IGF1/HTR2B/NOD2/CLEC5A/TLR1/EZR/TLR2/KCNN4/PTGER4/ARF6/WNT5A/CD58/IL17RA/FCN1/LILRA5/GAPDH/TNFRSF14/NLRP3/CLEC4E/PPARD/MBP/MIF/CD2/WLS/LILRA2/IL4R/NLRP12/RGCC/JAK2/P2RX7/ADAM8/TNF/IL1RAP/AIM2/TRIM16/TGFB1/PPP3CB/EXOC1/AACS/UNC13B/ARRB1/HIF1A/FFAR2/FRMD8/PANX1/HYAL2/MCU/TLR4/DDX58/PTPN22/FGR/HLA-E/ABL1/IL1B/AIF1/AGER/RASGRP1/DHX9/C2CD2L/MMP12/MPC2/LRP1/HMGB1/TRPM4/DOC2B/GPI/RAC1/GLUD1/SPTBN1/MAVS/IL6/IRS2/LRRK2/GLMN/SERP1/SRI/ARF1/OXCT1/ALOX15B/IFIH1/RPH3AL/GOLPH3L/GPR27/ABCG1/IL1A/CASP1/SYTL4/OSM/CD274/PDX1/LGALS9/TM7SF3/FZD5/CD2AP/PFKFB2/F2R/DNM1L/CRTAM/IFNGR1/EGFR/ADAM9/TNFSF4/GIPR/TLR8/TCF7L2/BAD/TREM2/PLA2G6/TNFRSF4/FRMD4A/TGFB3/NLRP1/HAVCR2/TSLP/IFNG/MAPK11/KIF5B/CD34/NLRP2/TRIM6/CD33/PRKCZ/CSF1R/SCAMP5/TRPV4/SOX4/CCL19/CHUK/CD244/GCG/NLGN2/IL26/GJA1/SEC24A/HMGB4/IL17RB/NR1H4/TARDBP/UCN3/RBP4/PSMD9/C1QTNF3/IL17RC/GHRL/IGHD/PHPT1	146
BP	GO:0022409	positive regulation of cell-cell adhesion	140/7096	255/18670	2.702e-08	4.59e-06	3.422e-06	IGF1/NOD2/PNP/CCR2/FYN/NFKBIZ/PTPN6/LILRB2/ANXA1/BCL10/LYN/CD55/WNT5A/CSK/EGR3/TNFRSF14/BCL6/NLRP3/SMAD7/DUSP10/FLOT1/CD44/ADAM19/IL4R/CBFB/MAP3K8/PTPRC/IL15/ADAM8/TNF/CD74/LILRB1/DPP4/IL7R/RELA/DOCK8/TGFB1/CCDC88B/KIFAP3/PTAFR/PAK1/SOCS5/LEP/TNFSF13B/FAM49B/CORO1A/LILRB4/TRAF6/ZBTB1/CXCL13/ITGA4/ZBTB7B/HLA-DPB1/HLA-DPA1/HLA-E/NCK1/CD209/NFKBID/PAK2/IL1B/AIF1/SIRPB1/AGER/CCL5/RASGRP1/RASAL3/PIK3R6/HLA-DMB/ICOSLG/HMGB1/EFNB1/IGFBP2/IL7/IL6ST/BMP7/TESPA1/HLA-G/RAC1/IL6/LCK/CYLD/FLOT2/CITED2/CTLA4/ETS1/VNN1/PDCD1LG2/CD47/LGALS1/CD1D/IL12RB1/GRB2/CD274/LGALS9/NFAT5/EBI3/ICOS/BTN2A2/DMTN/HES1/ADA/HLX/VAV1/IL18/FADD/AP3B1/CD276/TFRC/TNFSF4/SART1/SOCS1/SIRPG/BAD/MYO10/HAVCR2/IFNG/SKAP1/SPTA1/NR4A3/CD5/GCNT2/CD4/TNFRSF13C/IL12B/PRKCZ/CD80/PRKCQ/DENND6A/RHOA/CX3CL1/CD83/CCL19/MALT1/ZBTB16/CCR7/CD3E/PDCD1/CD24/IL23A/SERPINF2	140
BP	GO:0050663	cytokine secretion	133/7096	240/18670	2.813e-08	4.655e-06	3.471e-06	HTR2B/NOD2/S100A12/PNP/CLEC5A/FN1/TLR1/EZR/TLR2/PTGER4/IL27RA/ANXA1/IL1R2/LYN/RBPJ/WNT5A/GBP1/ARG2/SYT11/CD58/IL17RA/FCN1/LILRA5/GAPDH/TNFRSF14/NLRP3/CLEC4E/TNFAIP3/BANK1/MBP/MIF/CD2/LGR4/LILRA2/IL4R/NLRP12/RGCC/P2RX7/TNF/TNFRSF21/GBP5/IL1RAP/LILRB1/AIM2/LCP2/TRIM16/FFAR2/CD36/FRMD8/TLR5/PANX1/LEP/SERPINB1/MAPKBP1/HYAL2/TCIRG1/TLR4/DDX58/PTPN22/ZBTB7B/FGR/ABL1/ABCA1/IL1B/AIF1/AGER/RASGRP1/DHX9/MMP12/PML/ISG15/LRP1/HMGB1/CHI3L1/SPTBN1/MAVS/LRRK2/CD200R1/S100A13/GLMN/BTN3A2/ALOX15B/IFIH1/IL1A/FFAR4/CASP1/OSM/TLR10/CD274/LGALS9/RABGEF1/BTN2A2/FZD5/MCOLN2/CPTP/F2R/CRTAM/IFNGR1/PPP1R11/TLR8/SRGN/BTN3A1/APOA1/SOCS1/TNFRSF4/NLRP1/HAVCR2/TSLP/IFNG/MAPK11/CD34/NLRP2/TRIM6/PRKCZ/CSF1R/SCAMP5/FOXP1/TRPV4/C5AR2/CX3CL1/CCL19/CHUK/CD244/CCR7/IL26/HMGB4/IL17RB/NR1H4/TLR6/C1QTNF3/IL17RC/GHRL/IGHD	133
BP	GO:0048002	antigen processing and presentation of peptide antigen	109/7096	189/18670	2.934e-08	4.734e-06	3.529e-06	FCGR1B/FCGR1A/SLC11A1/CTSF/CTSD/PSMB9/ITGB5/KLC1/PSMB8/AP1B1/TAP2/DYNC1LI1/CTSS/TAP1/LGMN/SEC22B/BCAP31/PSMA5/HFE/PSMD11/CD74/PDIA3/PSME1/KIF3B/OSBPL1A/KIFAP3/SAR1B/PSMB10/CD36/CAPZA2/DYNLL2/PSMA1/PSMA4/NCF4/HLA-F/TRAF6/NCF2/CENPE/IKBKG/NCF1/HLA-DPB1/HLA-DPA1/HLA-E/HLA-B/CD209/VAMP3/PSMB1/PSMC4/CAPZA1/KIF4A/HLA-DMB/PSMD13/PSMB3/HLA-DOB/HLA-G/KIF2A/TAPBPL/HLA-DRA/AP1M2/TAPBP/HLA-DMA/HLA-C/PSMB5/PSMD6/ARF1/PSMC3/AP2A2/PSME3/DNM2/PSMC6/DCTN2/LAG3/AP2S1/CTSV/CYBA/CYBB/CTSE/CANX/AP2A1/CALR/AP1S3/AP1G1/HLA-DQB2/PSMC1/KIF2C/TREM2/ERAP1/PSMD8/HLA-A/PSMA2/AP1M1/ERAP2/SPTBN2/PSMC5/DYNC1LI2/KLC2/PSMC2/AP2M1/PSMB2/PSMD4/CHUK/DCTN6/PSMD1/PSMB4/DCTN5/SEC24A/PSMD9/PSMD3/HLA-DOA	109
BP	GO:0002218	activation of innate immune response	169/7096	319/18670	3.143e-08	4.948e-06	3.689e-06	MYD88/S100A9/S100A8/ITGAM/NOD2/FYN/ICAM2/TLR1/TLR2/CLEC7A/APPL2/BCL10/LYN/IRF7/TNIP2/IRF1/GRAMD4/ICAM3/CLEC4D/MNDA/HCK/FCN1/PSMB9/CUL1/CLEC4E/MARCO/TNFAIP3/RPS6KA3/PSMB8/CTSS/BIRC2/LY96/FLOT1/LGR4/LGMN/LILRA2/CTSK/UBE2N/PSMA5/PSMD11/PRKACB/DDX60/IRAK3/NFKBIA/NFKB1/KRAS/PSME1/AIM2/TICAM1/MAPKAPK3/RELA/HEXIM1/IRAK4/SIN3A/FFAR2/PAK1/PSMB10/CD36/TLR5/PSMA1/PSMA4/PRKCD/UBE2D3/TAB3/TRAF6/IKBKG/TLR4/DDX58/PTPN22/TRAF3/UBE2D2/CD209/PSPC1/CACTIN/HRAS/RELB/RSAD2/CASP8/PSMB1/PAK2/PSMC4/XRCC5/PLCG2/CD300LF/CTSB/PSMD13/HMGB1/MUC2/RAF1/PSMB3/SFPQ/MFHAS1/MAVS/CYLD/LSM14A/PUM2/PSMB5/PSMD6/TREML4/OTUD4/MUC1/PSMC3/NPLOC4/IFIH1/SEC14L1/TAB1/PSME3/MAPKAPK2/TNIP1/PSMC6/ANKRD17/BIRC3/NR1H3/PRKACA/NRAS/TNIP3/TLR10/ALPK1/UBC/CD300A/WDFY1/CYBA/PGLYRP4/RAB7B/DMBT1/C1QBP/FADD/GPATCH3/HSP90B1/TLR8/RIOK3/TIFA/MUC6/PSMC1/REG3G/XRCC6/PSMD8/HAVCR2/PSMA2/TRIM15/MAP3K1/NLRX1/MUCL1/TLR3/LBP/PSMC5/PSMC2/PSMB2/PSMD4/TYRO3/RTN4/UNC93B1/TSPAN6/MALT1/TIRAP/CHUK/XIAP/PSMD1/APPL1/PSMB4/ZCCHC3/HMGB4/NR1H4/TLR6/PSMD9/PSMD3/S100A14/RFTN1/MIR146A	169
BP	GO:0006090	pyruvate metabolic process	92/7096	154/18670	3.448e-08	5.298e-06	3.95e-06	IGF1/CBFA2T3/HK3/PDK4/LDHA/FBP1/PGK1/STAT3/PFKFB3/NUP62/NUP160/PFKM/PFKP/GAPDH/NUP214/SLC2A6/ME1/P2RX7/NUPR1/PGAM1/PKM/PDK2/GALK1/EIF6/TPI1/ZBTB7A/NUP85/HIF1A/SEH1L/PCK2/INSR/ALDOC/NUP43/ENO1/ALDOA/GSTZ1/ME3/POM121/MPC2/OGDH/HAGH/GPI/LDHB/PFKFB4/PPARGC1A/DHTKD1/SLC25A12/LDHC/PRKAG2/MYOG/NCOR1/LDHAL6B/PFKFB1/NUP88/HDAC4/NUP107/SLC16A1/PDK1/PDHB/FOXK2/DDIT4/PGK2/PFKFB2/ARNT/VDAC1/DLAT/PDP2/PPARA/NUP93/PRKAA1/PSEN1/PDHA2/NUP205/ENO2/SLC4A1/SRR/NUP50/IFNG/PRKAG1/OGT/NR4A3/PDP1/ESRRB/ZBTB20/PC/ADPGK/ME2/APP/PDPR/PFKL/POM121C/AAAS	92
BP	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	52/7096	75/18670	3.602e-08	5.406e-06	4.03e-06	FCGR1B/FCGR1A/PSMB9/ITGB5/PSMB8/TAP2/TAP1/SEC22B/PSMA5/PSMD11/PDIA3/PSME1/PSMB10/CD36/PSMA1/PSMA4/NCF4/HLA-F/NCF2/IKBKG/NCF1/HLA-E/HLA-B/VAMP3/PSMB1/PSMC4/PSMD13/PSMB3/HLA-G/TAPBP/HLA-C/PSMB5/PSMD6/PSMC3/PSME3/PSMC6/CYBA/CYBB/CALR/PSMC1/PSMD8/HLA-A/PSMA2/PSMC5/PSMC2/PSMB2/PSMD4/CHUK/PSMD1/PSMB4/PSMD9/PSMD3	52
BP	GO:0002758	innate immune response-activating signal transduction	159/7096	298/18670	4.29e-08	6.186e-06	4.612e-06	MYD88/S100A9/S100A8/ITGAM/NOD2/FYN/ICAM2/TLR1/TLR2/CLEC7A/APPL2/BCL10/LYN/IRF7/TNIP2/IRF1/GRAMD4/ICAM3/CLEC4D/HCK/FCN1/PSMB9/CUL1/CLEC4E/MARCO/TNFAIP3/RPS6KA3/PSMB8/CTSS/BIRC2/LY96/FLOT1/LGR4/LGMN/LILRA2/CTSK/UBE2N/PSMA5/PSMD11/PRKACB/DDX60/IRAK3/NFKBIA/NFKB1/KRAS/PSME1/TICAM1/MAPKAPK3/RELA/IRAK4/FFAR2/PAK1/PSMB10/CD36/TLR5/PSMA1/PSMA4/PRKCD/UBE2D3/TAB3/TRAF6/IKBKG/TLR4/DDX58/PTPN22/TRAF3/UBE2D2/CD209/CACTIN/HRAS/RELB/RSAD2/CASP8/PSMB1/PAK2/PSMC4/PLCG2/CD300LF/CTSB/PSMD13/HMGB1/MUC2/RAF1/PSMB3/MFHAS1/CYLD/LSM14A/PUM2/PSMB5/PSMD6/TREML4/OTUD4/MUC1/PSMC3/NPLOC4/IFIH1/SEC14L1/TAB1/PSME3/MAPKAPK2/TNIP1/PSMC6/ANKRD17/BIRC3/NR1H3/PRKACA/NRAS/TNIP3/TLR10/ALPK1/UBC/CD300A/WDFY1/CYBA/PGLYRP4/RAB7B/DMBT1/C1QBP/FADD/GPATCH3/HSP90B1/TLR8/RIOK3/TIFA/MUC6/PSMC1/REG3G/PSMD8/HAVCR2/PSMA2/TRIM15/MAP3K1/NLRX1/MUCL1/TLR3/LBP/PSMC5/PSMC2/PSMB2/PSMD4/TYRO3/RTN4/UNC93B1/TSPAN6/MALT1/TIRAP/CHUK/XIAP/PSMD1/APPL1/PSMB4/ZCCHC3/NR1H4/TLR6/PSMD9/PSMD3/S100A14/RFTN1/MIR146A	159
BP	GO:0006733	oxidoreduction coenzyme metabolic process	117/7096	207/18670	4.392e-08	6.186e-06	4.612e-06	IGF1/CBFA2T3/TALDO1/HK3/NAMPT/QPRT/BST1/LDHA/FBP1/PARP9/PGK1/MDH1/KCNAB2/STAT3/PFKFB3/NUP62/NUP160/PFKM/PTGS2/PFKP/GAPDH/NUP214/NMNAT3/SLC2A6/ME1/P2RX7/NUPR1/HMGCR/PGAM1/PKM/GALK1/RPE/EIF6/TPI1/ZBTB7A/TKT/NUP85/HIF1A/COQ7/COQ5/SEH1L/INSR/ALDOC/NUP43/RPIA/NMNAT1/ENO1/IDO1/ALDOA/PARP16/NADK2/PDSS1/POM121/MPC2/OGDH/COQ3/IDH1/GPI/LDHB/G6PD/PFKFB4/PPARGC1A/IDH2/KYNU/HAAO/DHTKD1/SLC25A12/PGM2/PRKAG2/MYOG/NCOR1/PFKFB1/NUP88/HDAC4/MDH1B/COQ10B/DERA/COQ9/NUP107/NMRK2/PDHB/COQ6/FOXK2/NMNAT2/DDIT4/PGK2/PFKFB2/ARNT/PPARA/NUP93/IDO2/SLC5A8/PRKAA1/PSEN1/NUP205/ENO2/SLC4A1/NUP50/IFNG/PRKAG1/OGT/PGD/ESRRB/ZBTB20/VCP/ADPGK/ME2/APP/FMO2/COQ10A/COQ4/PFKL/NNT/POM121C/AAAS/PGLS/RBKS	117
BP	GO:0045785	positive regulation of cell adhesion	206/7096	403/18670	4.409e-08	6.186e-06	4.612e-06	IGF1/MYADM/S100A10/NOD2/PNP/CCR2/FN1/FYN/NFKBIZ/PTPN6/LILRB2/ANXA1/APBB1IP/BCL10/LYN/CD55/WNT5A/TSC1/CSK/AZU1/ITGA5/EGR3/TNFRSF14/BCL6/NLRP3/NEDD9/FLNA/SMAD7/DUSP10/CIB1/FLOT1/CD44/ADAM19/IL4R/CBFB/JAK2/MAP3K8/PTPRC/LDB1/IL15/ADAM8/TNF/CD74/GSK3B/LILRB1/CXCL12/DPP4/IL7R/RELA/DOCK8/TGFB1/CCDC88B/KIFAP3/PTAFR/PAK1/SOCS5/CD36/PTK2B/LEP/TNFSF13B/FAM49B/CORO1A/LILRB4/TRAF6/ZBTB1/CXCL13/NINJ1/ITGA4/ZBTB7B/HLA-DPB1/HLA-DPA1/HLA-E/NCK1/VEGFA/CD209/ABL1/NFKBID/PAK2/IL1B/AIF1/SIRPB1/AGER/CCL5/RASGRP1/RASAL3/PIK3R6/HLA-DMB/P2RY12/ICOSLG/HMGB1/EFNB1/IGFBP2/IL7/CRK/TNFRSF18/PPM1F/IL6ST/BMP7/TESPA1/HLA-G/RAC1/TFE3/IL6/LCK/CYLD/FLOT2/CITED2/FLCN/DOCK5/RELL2/CTLA4/EMILIN3/ETS1/ATM/VNN1/PDCD1LG2/EMP2/NRP1/DISC1/TMEM102/PRKD2/DNM2/TPM1/TGM2/CD47/UNC13D/TRIOBP/LGALS1/ITGA2/CD1D/IL12RB1/SPOCK2/GRB2/CD274/LGALS9/NFAT5/EBI3/ICOS/BTN2A2/ITGA3/DMTN/HES1/ADA/HLX/CALR/C1QBP/VAV1/IL18/FADD/AP3B1/CD276/PREX1/TFRC/ADAM9/TNFSF4/SART1/EMID1/APOA1/SOCS1/SIRPG/BAD/MYO10/HAVCR2/IFNG/SKAP1/SPTA1/NR4A3/CD5/HRG/TNFSF18/RET/GCNT2/CD4/TNFRSF13C/IL12B/NID1/ARPC2/PRKCZ/CD80/MAP4K4/PRKCQ/DENND6A/RHOA/LIMS1/DAG1/IBSP/CX3CL1/ITGB1BP1/CD83/CCL19/MALT1/IFT74/ZBTB16/FOXF1/CCR7/CD3E/EMILIN2/PDCD1/PRKCA/CD24/IL23A/SERPINF2/PRSS2/HSD17B12/PTPRJ/FMN1	206
BP	GO:0046434	organophosphate catabolic process	136/7096	248/18670	4.661e-08	6.401e-06	4.772e-06	IGF1/PNP/CBFA2T3/HK3/UPP1/LDHA/FBP1/PGK1/ENPP2/STAT3/PFKFB3/NUP62/NUP160/PFKM/PFKP/GAPDH/GDE1/ABHD6/ABHD12/NUP214/GPCPD1/ACOT7/APOC1/SCARB1/SLC2A6/P2RX7/NUPR1/SMPDL3A/INPP1/PNPLA6/PGAM1/PKM/GALK1/EIF6/TPI1/HDDC3/ZBTB7A/NEIL2/NUP85/HIF1A/UNG/NUDT1/SEH1L/NT5C/SYNJ1/PRKCD/INSR/NAPEPLD/ALDOC/NUP43/PDE4B/ENO1/ALDOA/HINT1/PLA2G15/SAMHD1/PLCG2/LDLR/POM121/OGDH/IDH1/SYNJ2/NUDT9/GPI/OCRL/TDG/PFKFB4/PPARGC1A/MLYCD/DNPH1/PNPLA8/DHTKD1/ENPP7/SLC25A12/PGM2/PRKAG2/MYOG/NCOR1/NUDT3/PFKFB1/NUP88/INPP5K/IMPA2/HDAC4/PDE7A/PRDX6/DERA/NUDT5/NUP107/MTMR2/INPP5F/FOXK2/DDIT4/PGK2/PFKFB2/ADA/ARNT/NUDT7/PPARA/NUP93/PRKAA1/PSEN1/NUP205/ENO2/SLC4A1/NUP50/IFNG/PRKAG1/OGT/SMPD1/CNP/ESRRB/ZBTB20/GPX1/DCTPP1/VCP/ADPGK/PDE8A/APP/NT5M/UPP2/AMPD3/ABCD1/ABHD16A/SMPD2/DUT/NUDT16/PFKL/MBD4/POM121C/PDE8B/AAAS/NTSR1/INPP5A/SMUG1/IMPA1	136
BP	GO:2000106	regulation of leukocyte apoptotic process	56/7096	83/18670	4.888e-08	6.572e-06	4.899e-06	NOD2/TSC22D3/PIP/ANXA1/BCL10/LYN/IRF7/WNT5A/ARG2/BCL6/SLC46A2/KITLG/MIF/P2RX7/ADAM8/SLC7A11/CD74/PRELID1/LILRB1/CXCL12/IL7R/HCLS1/AXL/DOCK8/HIF1A/RAPGEF2/SLC39A10/IDO1/NFKBID/CCL5/SIRT1/IRS2/CCR5/FNIP1/BMP4/BAX/NOC2L/PIK3CD/CD3G/CD274/LGALS9/BIRC7/ADA/CXCR2/FADD/ADAM17/PTCRA/MERTK/NR4A3/PRKCQ/FOXP1/CCL19/CCR7/PDCD1/MEF2C/PIK3CB	56
BP	GO:0002793	positive regulation of peptide secretion	154/7096	288/18670	5.774e-08	7.605e-06	5.67e-06	IGF1/S100A8/HTR2B/NOD2/CLEC5A/TLR1/EZR/TLR2/KCNN4/PTGER4/ARF6/WNT5A/CD58/IL17RA/FCN1/LILRA5/GAPDH/TNFRSF14/NLRP3/CLEC4E/PPARD/MBP/MIF/CD2/WLS/LILRA2/IL4R/NLRP12/RGCC/JAK2/P2RX7/HFE/ADAM8/TNF/IL1RAP/AIM2/TRIM16/TGFB1/PPP3CB/EXOC1/AACS/UNC13B/ARRB1/HIF1A/FFAR2/FRMD8/PANX1/HYAL2/MCU/AIMP1/TLR4/DDX58/PTPN22/ITSN1/FGR/HLA-E/ABL1/IL1B/AIF1/AGER/RASGRP1/DHX9/C2CD2L/MMP12/MPC2/LRP1/HMGB1/TRPM4/DOC2B/GPI/RAC1/GLUD1/SPTBN1/MAVS/IL6/IRS2/LRRK2/GLMN/SERP1/SRI/ARF1/OXCT1/ALOX15B/IFIH1/RPH3AL/GOLPH3L/GPR27/ABCG1/IL1A/CASP1/SYTL4/OSM/CD274/PDX1/LGALS9/TM7SF3/FZD5/CD2AP/PFKFB2/F2R/DNM1L/CRTAM/IFNGR1/RAB8B/EGFR/ADAM9/TNFSF4/GIPR/TLR8/TCF7L2/BAD/TREM2/PLA2G6/TNFRSF4/FRMD4A/TGFB3/NLRP1/HAVCR2/TSLP/IFNG/MAPK11/KIF5B/CD34/NLRP2/TRIM6/CD33/PRKCZ/CSF1R/SCAMP5/TRPV4/GHRH/SOX4/CCL19/CHUK/CD244/GCG/NLGN2/IL26/GJA1/SEC24A/HMGB4/IL17RB/NR1H4/TARDBP/UCN3/RBP4/PSMD9/C1QTNF3/IL17RC/GHRL/IGHD/KISS1/APLN/PHPT1	154
BP	GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	87/7096	145/18670	6.081e-08	7.849e-06	5.852e-06	CCR2/NFKBIZ/PTPN6/IL27RA/ANXA1/STX7/MAD2L2/SLC11A1/STAT6/BCL6/NLRP3/SMAD7/TNFAIP3/CD40/CD1C/IL4R/PTPRC/P2RX7/CD1E/HFE/TNF/LILRB1/IL7R/CD226/TGFB1/PPP3CB/IL18R1/SOCS5/TNFSF13B/FAM49B/HLA-F/TRAF6/ZBTB1/CLC/IL20RB/ZBTB7B/HLA-E/HLA-B/RSAD2/NFKBID/IL1B/FBXO38/AGER/CD1B/HMGB1/TRPM4/IL1R1/HLA-G/IL6/CR1/HLA-C/FCER2/MLH1/PARP3/CLCF1/PVR/CD1D/IL12RB1/CD1A/CD274/FZD5/ADA/HLX/IL18/FADD/TRAF2/TFRC/TNFSF4/HLA-A/HAVCR2/EXOSC3/CD4/TNFRSF13C/IL12B/PRKCZ/CD80/TBX21/PRKCQ/APLF/EXOSC6/CCL19/MALT1/WAS/PAXIP1/ATAD5/IL23A/MEF2C	87
BP	GO:0051193	regulation of cofactor metabolic process	74/7096	119/18670	7.376e-08	9.334e-06	6.959e-06	IGF1/CBFA2T3/FYN/RAC2/PDK4/PINK1/FBP1/STAT3/PFKFB3/NUP62/NUP160/NUP214/SLC2A6/ME1/P2RX7/SLC7A11/NUPR1/PGAM1/PDK2/EIF6/ZBTB7A/NUP85/HIF1A/SEH1L/INSR/MPV17L/NUP43/GSTZ1/TMEM14C/SRRD/POM121/COQ3/RAC1/NOXA1/PFKFB4/PPARGC1A/SLC25A12/PRKAG2/MYOG/NCOR1/PFKFB1/NUP88/HDAC4/MMP3/NUP107/PDK1/DDIT4/PFKFB2/ARNT/NFE2L2/PDP2/PPARA/NUP93/CLYBL/PRKAA1/PSEN1/NUP205/NUP50/IFNG/PRKAG1/OGT/HP/PDP1/DUOXA1/ESRRB/ZBTB20/ME2/APP/SNCA/PDPR/CTNS/NNT/POM121C/AAAS	74
BP	GO:0034404	nucleobase-containing small molecule biosynthetic process	125/7096	226/18670	8.417e-08	1.045e-05	7.788e-06	TYMP/IGF1/PNP/CBFA2T3/HK3/UPP1/LDHA/FBP1/PGK1/STAT3/PFKFB3/NUP62/NUP160/PFKM/PFKP/GAPDH/NUP214/ACOT7/SLC2A6/P2RX7/NUPR1/SMPDL3A/PGAM1/PKM/GALK1/EIF6/TPI1/HDDC3/ZBTB7A/GMPS/NEIL2/NUP85/HIF1A/UNG/NUDT1/SEH1L/NT5C/ADK/INSR/ALDOC/GUK1/NUP43/IMPDH1/CTPS2/PDE4B/ENO1/ALDOA/HINT1/SAMHD1/CMPK1/TK1/POM121/OGDH/NUDT9/GPI/PRTFDC1/TDG/PFKFB4/PPARGC1A/MLYCD/DNPH1/DHTKD1/NME3/MTAP/SLC25A12/NME4/PRKAG2/MYOG/NCOR1/NUDT3/PFKFB1/NUP88/HDAC4/PDE7A/NME1/DERA/NUDT5/NUP107/FOXK2/DDIT4/PGK2/PFKFB2/ADA/DCK/ARNT/NUDT7/UCK1/PPARA/NUP93/TK2/PRKAA1/PSEN1/NUP205/ENO2/SLC4A1/CTPS1/CAD/NUP50/IFNG/PRKAG1/OGT/CNP/ESRRB/ZBTB20/CDA/GPX1/DCTPP1/VCP/ADPGK/UCKL1/PDE8A/APP/NT5M/UPP2/AMPD3/ABCD1/ADAL/DUT/NUDT16/PFKL/MBD4/POM121C/PDE8B/AAAS/SMUG1	125
BP	GO:0002478	antigen processing and presentation of exogenous peptide antigen	101/7096	175/18670	8.853e-08	1.078e-05	8.037e-06	FCGR1B/FCGR1A/CTSF/CTSD/PSMB9/ITGB5/KLC1/PSMB8/AP1B1/TAP2/DYNC1LI1/CTSS/TAP1/LGMN/SEC22B/PSMA5/PSMD11/CD74/PDIA3/PSME1/KIF3B/OSBPL1A/KIFAP3/SAR1B/PSMB10/CD36/CAPZA2/DYNLL2/PSMA1/PSMA4/NCF4/HLA-F/TRAF6/NCF2/CENPE/IKBKG/NCF1/HLA-DPB1/HLA-DPA1/HLA-E/HLA-B/VAMP3/PSMB1/PSMC4/CAPZA1/KIF4A/HLA-DMB/PSMD13/PSMB3/HLA-DOB/HLA-G/KIF2A/HLA-DRA/AP1M2/TAPBP/HLA-DMA/HLA-C/PSMB5/PSMD6/ARF1/PSMC3/AP2A2/PSME3/DNM2/PSMC6/DCTN2/LAG3/AP2S1/CTSV/CYBA/CYBB/CTSE/CANX/AP2A1/CALR/AP1S3/AP1G1/HLA-DQB2/PSMC1/KIF2C/PSMD8/HLA-A/PSMA2/AP1M1/SPTBN2/PSMC5/DYNC1LI2/KLC2/PSMC2/AP2M1/PSMB2/PSMD4/CHUK/DCTN6/PSMD1/PSMB4/DCTN5/SEC24A/PSMD9/PSMD3/HLA-DOA	101
BP	GO:0007159	leukocyte cell-cell adhesion	175/7096	337/18670	1.13e-07	1.347e-05	1.004e-05	KLF4/IGF1/S100A9/S100A8/NOD2/PNP/CCR2/FYN/CX3CR1/EZR/RAC2/NFKBIZ/PTPN6/LILRB2/SELL/ANXA1/BCL10/LYN/CD55/IRF1/CSK/ARG2/ITGA5/GPNMB/EGR3/PTPN2/ITGB7/TNFRSF14/BCL6/NLRP3/SMAD7/DUSP10/FGL2/CD44/IL4R/CEBPB/CBFB/MAP3K8/PTPRC/IL15/HFE/ADAM8/TNF/CD74/TNFRSF21/LILRB1/CXCL12/DPP4/DUSP3/IL7R/RELA/DOCK8/TGFB1/CCDC88B/PTAFR/PAK1/SOCS5/LEP/ITGAL/TNFSF13B/FAM49B/CORO1A/LILRB4/TRAF6/ZBTB1/ITGA4/IL20RB/PTPN22/ZBTB7B/SOCS6/HLA-DPB1/HLA-DPA1/HLA-E/NCK1/DTX1/CD209/CASP3/IDO1/NFKBID/PAK2/IL1B/AIF1/SIRPB1/AGER/CCL5/RASGRP1/RASAL3/PIK3R6/SEMA4D/HLA-DMB/ICOSLG/HMGB1/EFNB1/IGFBP2/IL7/IL6ST/BMP7/TESPA1/HLA-G/RAC1/IL6/LCK/CYLD/FLOT2/CTLA4/GLMN/GCNT1/ETS1/SELPLG/TIGIT/VSIG4/SCGB1A1/VNN1/PDCD1LG2/NRARP/BMP4/TNIP1/CD47/MADCAM1/LGALS1/LAG3/CD1D/IL12RB1/GRB2/CD300A/CD274/LGALS9/LAX1/NFAT5/EBI3/ICOS/BTN2A2/HES1/ADA/HLX/CERCAM/VAV1/IL18/PPARA/FADD/AP3B1/CD276/TFRC/TNFSF4/SART1/PAG1/MSN/SOCS1/SIRPG/BAD/HAVCR2/IFNG/SKAP1/SPTA1/NR4A3/CD5/CD4/TNFRSF13C/IL12B/PRKCZ/CD80/TBX21/PRKCQ/RHOA/CD83/CCL19/MALT1/ZBTB16/CCR7/CD3E/PDCD1/TWSG1/CD24/IL23A/MIR146A	175
BP	GO:0034341	response to interferon-gamma	112/7096	199/18670	1.148e-07	1.347e-05	1.004e-05	FCGR1B/CDC42EP4/TLR2/GBP2/GCH1/SOCS3/IRF7/PARP9/FCGR1A/SLC11A1/IRF1/WNT5A/GBP1/CD58/PTPN2/VIM/HCK/GAPDH/NLRC5/STAT1/CD44/JAK2/OASL/IFITM2/IFITM1/GBP5/IFITM3/ACTR2/TRIM68/IFNGR2/EVL/CDC37/NMI/STXBP1/CDC42EP2/PTAFR/TRIM22/IRF9/STXBP2/NR1H2/GBP4/PRKCD/HLA-F/NCAM1/TRIM26/TLR4/HLA-DPB1/OAS3/HLA-DPA1/HLA-E/HLA-B/VAMP3/SP100/AIF1/CCL5/RAB20/DAPK1/PML/OAS2/CCL7/RAB43/HLA-G/HLA-DRA/MYO1C/SUMO1/KYNU/HLA-C/KIF16B/ZYX/CCL13/TRIM21/MEFV/CCL8/CD47/NR1H3/CASP1/IL12RB1/LGALS9/RAB7B/IRF2/CAMK2A/ACTR3/FLNB/CAMK2D/IRF8/IFNGR1/CCL20/CCL26/HLA-DQB2/CYP27B1/SOCS1/HLA-A/IFNG/JAK1/STX8/KIF5B/TXK/GBP6/HSP90AB1/TLR3/IL12B/STXBP3/VPS26B/SNCA/CX3CL1/CCL19/CCL4/WAS/CCL24/SYNCRIP/STXBP4/CAMK2B	112
BP	GO:0071346	cellular response to interferon-gamma	103/7096	180/18670	1.198e-07	1.381e-05	1.03e-05	FCGR1B/CDC42EP4/TLR2/GBP2/SOCS3/IRF7/PARP9/FCGR1A/IRF1/WNT5A/GBP1/CD58/PTPN2/VIM/HCK/GAPDH/NLRC5/STAT1/CD44/JAK2/OASL/GBP5/ACTR2/TRIM68/IFNGR2/EVL/CDC37/NMI/STXBP1/CDC42EP2/PTAFR/TRIM22/IRF9/STXBP2/NR1H2/GBP4/PRKCD/HLA-F/NCAM1/TRIM26/TLR4/HLA-DPB1/OAS3/HLA-DPA1/HLA-E/HLA-B/VAMP3/SP100/AIF1/CCL5/RAB20/DAPK1/PML/OAS2/CCL7/RAB43/HLA-G/HLA-DRA/MYO1C/SUMO1/HLA-C/KIF16B/ZYX/CCL13/TRIM21/CCL8/CD47/NR1H3/CASP1/IL12RB1/LGALS9/RAB7B/IRF2/CAMK2A/ACTR3/FLNB/CAMK2D/IRF8/IFNGR1/CCL20/CCL26/HLA-DQB2/SOCS1/HLA-A/IFNG/JAK1/STX8/KIF5B/TXK/GBP6/HSP90AB1/TLR3/IL12B/STXBP3/VPS26B/CX3CL1/CCL19/CCL4/WAS/CCL24/SYNCRIP/STXBP4/CAMK2B	103
BP	GO:0050707	regulation of cytokine secretion	117/7096	210/18670	1.274e-07	1.443e-05	1.076e-05	HTR2B/NOD2/CLEC5A/FN1/TLR1/EZR/TLR2/PTGER4/IL27RA/ANXA1/IL1R2/LYN/WNT5A/GBP1/ARG2/SYT11/CD58/IL17RA/FCN1/LILRA5/GAPDH/TNFRSF14/NLRP3/CLEC4E/TNFAIP3/BANK1/MBP/MIF/CD2/LGR4/LILRA2/IL4R/NLRP12/RGCC/P2RX7/TNF/TNFRSF21/IL1RAP/LILRB1/AIM2/TRIM16/FFAR2/FRMD8/TLR5/PANX1/SERPINB1/MAPKBP1/HYAL2/TLR4/DDX58/PTPN22/FGR/ABL1/IL1B/AIF1/AGER/RASGRP1/DHX9/MMP12/PML/LRP1/HMGB1/SPTBN1/MAVS/LRRK2/CD200R1/GLMN/ALOX15B/IFIH1/IL1A/FFAR4/CASP1/OSM/TLR10/CD274/LGALS9/RABGEF1/BTN2A2/FZD5/CPTP/F2R/CRTAM/IFNGR1/PPP1R11/TLR8/SRGN/APOA1/SOCS1/TNFRSF4/NLRP1/HAVCR2/TSLP/IFNG/MAPK11/CD34/NLRP2/TRIM6/PRKCZ/CSF1R/SCAMP5/FOXP1/TRPV4/C5AR2/CX3CL1/CCL19/CHUK/CD244/CCR7/IL26/HMGB4/IL17RB/NR1H4/TLR6/C1QTNF3/IL17RC/GHRL/IGHD	117
BP	GO:0034599	cellular response to oxidative stress	159/7096	302/18670	1.351e-07	1.489e-05	1.11e-05	KLF4/NQO1/EPAS1/FOS/KLF2/FYN/ANXA1/GCH1/ATG7/NR4A2/PINK1/AIFM1/TSC1/SOD1/STAT6/ZNF622/ADNP2/PLEKHA1/TNFAIP3/FBXW7/MTR/JAK2/GSTP1/PSAP/TNF/SLC7A11/EZH2/HMOX1/GSR/VRK2/MPV17/AKR1C3/PKD2/TXNRD1/ATF4/GPX7/RELA/PDK2/AXL/SIN3A/CYP1B1/HGF/HIF1A/MAP1LC3A/HSPB1/CD36/PRDX1/MAPK7/NCF4/PCGF2/PRKCD/MAPK13/STAU1/NCF2/TMEM161A/NCF1/MCL1/HTRA2/TLR4/NET1/CAT/ABL1/NCOA7/AIF1/GPX3/DAPK1/PML/ADPRHL2/CRK/SIRT1/SFPQ/BMP7/TRPM2/EIF2S1/OSER1/ETV5/IL6/LRRK2/G6PD/PPARGC1A/ETS1/MIR34A/SETX/SPHK1/VNN1/HDAC2/MGST1/RAD52/MAPK8/MMP9/ZNF580/BCL2/DNM2/CHD6/PCNA/TPM1/MSRB3/PRDX6/MMP3/MGAT3/PDK1/GSKIP/CYBA/CYBB/HNRNPD/FER/MAP3K5/KDM6B/ARNT/UCP1/FZD1/PXN/NFE2L2/IMPACT/NFE2L1/DHFR/EGFR/TXN/TRAF2/ATP2A2/WNT1/PRKAA1/MDM2/MAPK1/ARNTL/NR4A3/ATP7A/FANCD2/SLC25A24/MAPKAP1/CCNA2/LANCL1/AGAP3/DIABLO/MMP2/GPX1/IL18RAP/PDE8A/SNCA/BAG5/PDCD10/ABCD1/SRXN1/SIGMAR1/MET/PNPT1/CHUK/MGMT/ENDOG/MPO/SESN2/TLR6/ERCC6L2/CPEB2/PDGFD/FOXO3/OXR1/MAPK9/ZNF277	159
BP	GO:0006979	response to oxidative stress	225/7096	451/18670	1.361e-07	1.489e-05	1.11e-05	KLF4/NQO1/SLC8A1/EPAS1/FOS/KLF2/FYN/DUSP1/ANXA1/GCH1/LDHA/ATG7/NR4A2/PINK1/GCLM/TXNIP/OXSR1/AIFM1/TSC1/SOD1/SLC23A2/STAT6/ZNF622/CAPN2/ADNP2/PTGS2/PDLIM1/PLEKHA1/TNFAIP3/FBXW7/STAT1/MTR/ALS2/JAK2/GSTP1/PSAP/TNF/SLC7A11/EZH2/HMOX1/GSR/VRK2/ERCC6/MPV17/AKR1C3/PKD2/APOE/ATOX1/TXNRD1/ATF4/GPX7/RELA/PDK2/AXL/UBE3A/SIN3A/CLN8/ALAD/CYP1B1/HGF/HIF1A/NUDT1/MAP1LC3A/HSPB1/CD36/PTK2B/PRDX1/MAPK7/NCF4/PCGF2/PRKCD/HBB/MAPK13/STAU1/HYAL2/NCF2/TMEM161A/KPNA4/NCF1/MCL1/HTRA2/TLR4/NET1/EGLN1/CAT/CASP3/ABL1/GCLC/APTX/NCOA7/AIF1/ATRN/ETFDH/GPX3/DAPK1/IPCEF1/PML/ADPRHL2/IDH1/ACOX2/CRK/SIRT1/SFPQ/PPP1R15B/BMP7/GPX4/TRPM2/EIF2S1/OSER1/ETV5/IL6/MTF1/LRRK2/G6PD/PPARGC1A/PSMB5/ETS1/MIR34A/SETX/TOR1A/SPHK1/SCGB1A1/VNN1/HDAC2/BTG1/PLK3/MGST1/RAD52/MAPK8/MMP9/ZNF580/BCL2/DNM2/CHD6/PCNA/XRCC1/TPM1/RGS14/ERCC1/MSRB3/PRDX6/MMP3/MGAT3/GSS/PDK1/GSKIP/CYBA/CYBB/HNRNPD/FER/MMP14/MAP3K5/HNRNPM/KDM6B/ADA/ARNT/UCP1/CHRNA4/FZD1/PXN/NFE2L2/IMPACT/NFE2L1/DHFR/EGFR/TXN/RRM2B/TRAF2/SESN1/ATP2A2/ADAM9/GGT7/WNT1/PRKAA1/PSEN1/MDM2/MAPK1/ERCC2/BAD/FOSL1/ARNTL/NR4A3/ATP7A/HP/FANCD2/SLC25A24/MAPKAP1/CCNA2/LANCL1/AGAP3/DIABLO/MMP2/GPX1/IL18RAP/PDE8A/APP/SNCA/BAG5/PDCD10/ABCD1/SRXN1/CCL19/SIGMAR1/MET/PNPT1/BAK1/CHUK/MGMT/CCR7/ENDOG/MPO/NDUFS2/PNKP/SESN2/TLR6/ERCC6L2/PTGS1/CPEB2/PDGFD/FOXO3/HAO1/OXR1/MAPK9/ZNF277/ERCC8	225
BP	GO:0051092	positive regulation of NF-kappaB transcription factor activity	88/7096	149/18670	1.413e-07	1.515e-05	1.129e-05	MYD88/S100A9/S100A8/NOD2/S100A12/TRIM32/CX3CR1/TLR2/BCL10/WNT5A/STAT3/NLRP3/CD40/DDRGK1/CIB1/FLOT1/ALK/UBE2N/ADAM8/TNF/IRAK3/NFKB1/TRIM13/IL1RAP/KRAS/AIM2/TICAM1/RELA/TRIM37/ZBTB7A/IRAK4/TGFB1/IL18R1/TRIM22/CD36/LRRFIP1/TAB3/TRAF6/NFKB2/IKBKG/TLR4/CARD14/CAT/NPM1/IL1B/AGER/DHX9/ARHGEF2/TNFRSF11A/TRADD/CLU/RBCK1/FLOT2/EDA/SPHK1/TAB1/TRAPPC9/PRKD2/CTH/ROR1/UBC/LGALS9/FER/RAB7B/TRAF1/CAMK2A/EIF2AK2/IL18/MID2/TRAF2/CLOCK/TRAF5/CAPN3/MAP3K13/TNFSF18/TRIM15/TLR3/CARM1/MTDH/PRKCZ/PRKCQ/IL18RAP/APP/CX3CL1/MALT1/TIRAP/CHUK/TLR6	88
BP	GO:0019362	pyridine nucleotide metabolic process	107/7096	189/18670	1.455e-07	1.515e-05	1.129e-05	IGF1/CBFA2T3/TALDO1/HK3/NAMPT/QPRT/BST1/LDHA/FBP1/PARP9/PGK1/MDH1/KCNAB2/STAT3/PFKFB3/NUP62/NUP160/PFKM/PTGS2/PFKP/GAPDH/NUP214/NMNAT3/SLC2A6/ME1/P2RX7/NUPR1/PGAM1/PKM/GALK1/RPE/EIF6/TPI1/ZBTB7A/TKT/NUP85/HIF1A/SEH1L/INSR/ALDOC/NUP43/RPIA/NMNAT1/ENO1/IDO1/ALDOA/PARP16/NADK2/POM121/MPC2/OGDH/IDH1/GPI/LDHB/G6PD/PFKFB4/PPARGC1A/IDH2/KYNU/HAAO/DHTKD1/SLC25A12/PGM2/PRKAG2/MYOG/NCOR1/PFKFB1/NUP88/HDAC4/MDH1B/DERA/NUP107/NMRK2/PDHB/FOXK2/NMNAT2/DDIT4/PGK2/PFKFB2/ARNT/PPARA/NUP93/IDO2/SLC5A8/PRKAA1/PSEN1/NUP205/ENO2/SLC4A1/NUP50/IFNG/PRKAG1/OGT/PGD/ESRRB/ZBTB20/VCP/ADPGK/ME2/APP/FMO2/PFKL/NNT/POM121C/AAAS/PGLS/RBKS	107
BP	GO:0046496	nicotinamide nucleotide metabolic process	107/7096	189/18670	1.455e-07	1.515e-05	1.129e-05	IGF1/CBFA2T3/TALDO1/HK3/NAMPT/QPRT/BST1/LDHA/FBP1/PARP9/PGK1/MDH1/KCNAB2/STAT3/PFKFB3/NUP62/NUP160/PFKM/PTGS2/PFKP/GAPDH/NUP214/NMNAT3/SLC2A6/ME1/P2RX7/NUPR1/PGAM1/PKM/GALK1/RPE/EIF6/TPI1/ZBTB7A/TKT/NUP85/HIF1A/SEH1L/INSR/ALDOC/NUP43/RPIA/NMNAT1/ENO1/IDO1/ALDOA/PARP16/NADK2/POM121/MPC2/OGDH/IDH1/GPI/LDHB/G6PD/PFKFB4/PPARGC1A/IDH2/KYNU/HAAO/DHTKD1/SLC25A12/PGM2/PRKAG2/MYOG/NCOR1/PFKFB1/NUP88/HDAC4/MDH1B/DERA/NUP107/NMRK2/PDHB/FOXK2/NMNAT2/DDIT4/PGK2/PFKFB2/ARNT/PPARA/NUP93/IDO2/SLC5A8/PRKAA1/PSEN1/NUP205/ENO2/SLC4A1/NUP50/IFNG/PRKAG1/OGT/PGD/ESRRB/ZBTB20/VCP/ADPGK/ME2/APP/FMO2/PFKL/NNT/POM121C/AAAS/PGLS/RBKS	107
BP	GO:1903532	positive regulation of secretion by cell	202/7096	399/18670	1.504e-07	1.54e-05	1.148e-05	IGF1/ITGAM/HTR2B/NOD2/CLEC5A/TLR1/EZR/STAM/TLR2/KCNN4/RAB9A/PTGER4/ARF6/PINK1/WNT5A/RETN/ATP6AP1/CD58/IL17RA/FCN1/LILRA5/GAPDH/TNFRSF14/SPP1/NLRP3/CLEC4E/PPARD/MBP/MIF/CD2/WLS/LILRA2/IL4R/NLRP12/RGCC/STXBP5/JAK2/P2RX7/HFE/ADAM8/LAMP1/TNF/IL1RAP/AIM2/CXCL12/TRIM16/TGFB1/PPP3CB/EXOC1/STXBP1/AACS/UNC13B/ARRB1/HIF1A/PTAFR/FFAR2/FRMD8/PANX1/LEP/HLA-F/HYAL2/MCU/AIMP1/TLR4/DDX58/PTPN22/ITSN1/FGR/HLA-E/CDK5/ABL1/RAB3GAP1/IL1B/DTNBP1/AIF1/AGER/RASGRP1/DHX9/C2CD2L/SDCBP/MMP12/MPC2/LRP1/HMGB1/CREB1/TRPM4/DOC2B/GPI/RAC1/GLUD1/SPTBN1/MAVS/IL6/IRS2/LRRK2/GLMN/SERP1/SRI/ARF1/OXCT1/ALOX15B/IFIH1/ADORA2B/RPH3AL/GOLPH3L/CHMP2A/GPR27/TSG101/ABCG1/UNC13D/RAB5A/IL1A/CASP1/SYTL4/OSM/INHBA/HGS/CD274/PDX1/LGALS9/TM7SF3/HYAL3/VPS4B/FZD5/CD2AP/PFKFB2/F2R/DNM1L/CRTAM/CDK5R2/CLASP2/IFNGR1/RAB8B/EGFR/NMB/ADAM9/TNFSF4/GIPR/AP1G1/TLR8/RAB3A/GALR1/CHRNB2/TCF7L2/BAD/SYT9/TREM2/PLA2G6/TNFRSF4/FRMD4A/TGFB3/NLRP1/HAVCR2/TSLP/IFNG/VIP/MAPK11/SYT1/KIF5B/CD34/INHA/SNX4/NLRP2/TRIM6/SYT4/CD33/PRKCZ/CADPS2/CSF1R/SCAMP5/TRPV4/GHRH/RAB3D/SNCA/SOX4/CCL19/CHUK/CD244/GCG/NLGN2/IL26/GJA1/CACNA1H/SEC24A/HMGB4/IL17RB/NR1H4/TARDBP/UCN3/RAB27A/RBP4/PSMD9/C1QTNF3/P2RY1/IL17RC/TACR2/NTSR1/GHRL/IGHD/KISS1/APLN/PHPT1	202
BP	GO:0009108	coenzyme biosynthetic process	140/7096	261/18670	1.778e-07	1.793e-05	1.337e-05	IGF1/CBFA2T3/HK3/NAMPT/QPRT/PDK4/GCH1/LDHA/FBP1/PARP9/PGK1/MMADHC/CBR4/STAT3/PFKFB3/NUP62/NUP160/PFKM/PTGS2/PFKP/GAPDH/PANK2/NUP214/ACOT7/NMNAT3/ACSL5/SLC2A6/P2RX7/PCBD1/ELOVL5/NUPR1/PGAM1/PKM/PDK2/GALK1/NFS1/EIF6/TPI1/ZBTB7A/NUP85/HIF1A/COQ7/COQ5/SCD/SEH1L/PANK3/AKR1A1/INSR/ALDOC/PANK1/NUP43/ACSL4/ACLY/NMNAT1/ENO1/IDO1/ALDOA/GSTZ1/PARP16/NADK2/PDSS1/TECR/POM121/MPC2/QDPR/ACACB/RFK/OGDH/TPK1/COQ3/ELOVL7/MOCS2/GPI/PTS/PFKFB4/PPARGC1A/MLYCD/IDH2/KYNU/HAAO/SPR/DHTKD1/ACSL6/PRKAG2/MYOG/NCOR1/PFKFB1/ATIC/NUP88/HDAC4/COQ10B/COQ9/NUP107/PDK1/NMRK2/PDHB/COQ6/FOXK2/NMNAT2/DDIT4/FLAD1/PGK2/PFKFB2/MOCS3/ARNT/DLAT/PDP2/DHFR/PPARA/NUP93/IDO2/SLC5A8/PRKAA1/PSEN1/PDHA2/NUP205/ENO2/SLC25A16/SLC4A1/FPGS/NUP50/IFNG/PRKAG1/OGT/PDP1/ESRRB/ZBTB20/PCBD2/ADPGK/APP/SNCA/COQ10A/ELOVL6/COQ4/PDPR/PFKL/MAT1A/POM121C/AAAS/HSD17B12	140
BP	GO:0048872	homeostasis of number of cells	133/7096	246/18670	1.969e-07	1.955e-05	1.457e-05	SH2B2/EPAS1/SLC40A1/TSC22D3/CCR2/KLF2/ANXA1/SKIL/SPI1/BCL10/LYN/ZFP36/SOD1/JMJD6/STAT3/PTPN2/LYAR/THRA/BCL6/SMAD5/PMAIP1/SLC46A2/TNFAIP3/KITLG/MIF/LIPA/CEBPG/STAT1/LGR4/JAK2/LDB1/P2RX7/SLC7A11/EZH2/DOCK10/CD74/HMOX1/GIGYF2/KRAS/TMOD3/IL7R/HCLS1/AXL/FAM210B/ZBTB7A/TGFB1/PPP3CB/HIF1A/PRDX1/TNFSF13B/SRF/CORO1A/NAPEPLD/FLT3LG/TCIRG1/IL20RB/FLT3/VEGFA/PDE4B/CASP3/ABL1/TMEM14C/ISG15/HMGB1/IL7/RPS24/MFHAS1/KLF13/IL6/ACVR1B/CYLD/G6PD/TAL1/BCR/ETS1/IKZF1/RPS19/KMT2E/BCL2L11/BCL2/BMP4/FH/BAX/HMGB2/PIK3CD/ID2/SFXN1/PPP2R3C/INHBA/CCR4/LGALS9/IREB2/DMTN/ADA/ARNT/F2R/DYRK3/NFE2L1/CXCR2/FADD/ADAM17/JAM3/DOCK11/TNFRSF13B/MERTK/ERCC2/SLC4A1/EPB42/SPTA1/BAP1/RB1/INHA/GAPT/TNFRSF13C/POLB/GPR183/FOXN1/AMPD3/SLC25A38/ADAR/UBAP2L/BAK1/TRIM58/CCR7/PRMT1/SMO/CACNA1F/DNASE2/CXCL6/LAT/FOXO3/MEF2C/PIK3CB	133
BP	GO:0043405	regulation of MAP kinase activity	174/7096	337/18670	2.03e-07	1.979e-05	1.475e-05	IGF1/HTR2B/NOD2/S100A12/FPR1/PEA15/PTPN6/DUSP1/DUSP6/LYN/PPP2CA/WNT5A/DUSP5/CSK/SOD1/ERP29/FLT1/NUP62/DUSP10/CD40/KITLG/MIF/MAP2K1/RGS2/UCHL1/DUSP7/JAK2/GSTP1/MAP3K8/PTPRC/P2RX7/MAGED1/ALK/UBE2N/ADAM8/DVL2/TNF/EZH2/IRAK3/CD74/EPHB2/AKAP13/ERCC6/KRAS/APOE/ZEB2/MAP3K4/HMGCR/DUSP3/MAPKAPK3/TGFB1/TAOK3/GADD45B/HGF/ARRB1/PAK1/MAP4K5/DUSP18/PTK2B/PRKCD/ROR2/INSR/TAB3/NRG1/TRAF6/HYAL2/IKBKG/MBIP/DUSP2/TLR4/PTPN22/FLT3/PDGFC/TPD52L1/BMP2/IGF1R/VEGFA/HRAS/IL1B/CSPG4/DTNBP1/AGER/MAP3K12/RASGRP1/PAQR3/MDFIC/SHC1/PIK3R6/TNFRSF11A/PDE6G/CRK/RAF1/BMP7/DUSP19/MAP4K2/MAP4K3/PDGFB/LRRK2/FGF1/PROK1/DUSP14/RGS3/DUSP4/MAPKAPK5/TAB1/ADORA2B/MAPKAPK2/BMP4/INPP5K/RGS14/TSG101/TRIB2/MAP3K6/MAP4K1/LPAR3/HGS/MLKL/UBC/MAP2K2/MAP3K11/CD300A/LAX1/PDGFA/FZD5/BIRC7/LPAR1/MAP3K5/PROK2/SPRY1/F2R/MOS/SPRED1/EIF2AK2/EGFR/MUL1/CAV3/TRAF2/FZD4/ADAM9/SPRY2/PRKAA1/PSEN1/MAPK1/MAP2K4/TGFB3/MAP3K13/PPEF2/MAPK11/HIPK3/DNAJA1/RET/MAP3K1/SMPD1/MAP2K5/PIK3CG/GPS1/LIME1/ERN1/PDCD4/PDCD10/CCL19/AIDA/GHR/DAXX/CD24/TLR6/PDGFD/GHRL/FZD10/PIK3CB/PTPRJ/NRK/SASH1/MAP3K9	174
BP	GO:0002709	regulation of T cell mediated immunity	48/7096	70/18670	2.054e-07	1.979e-05	1.475e-05	CCR2/STX7/NLRP3/SMAD7/CD1C/PTPRC/P2RX7/CD1E/HFE/LILRB1/IL7R/PPP3CB/IL18R1/FAM49B/HLA-F/TRAF6/ZBTB1/CLC/IL20RB/HLA-E/HLA-B/RSAD2/IL1B/FBXO38/AGER/CD1B/HMGB1/TRPM4/IL1R1/HLA-G/IL6/HLA-C/PVR/CD1D/IL12RB1/CD1A/FZD5/IL18/FADD/TRAF2/TNFSF4/HLA-A/IL12B/PRKCZ/TBX21/MALT1/WAS/IL23A	48
BP	GO:0051607	defense response to virus	129/7096	238/18670	2.475e-07	2.349e-05	1.751e-05	RNASE2/ATG7/IRF7/PARP9/IRF1/DDX21/AZU1/GBP1/PLSCR1/NLRP3/FLNA/PMAIP1/TNFAIP3/NLRC5/CD40/BIRC2/FGL2/STAT1/CXCL9/OASL/PTPRC/IL15/IFITM2/SLFN11/IFITM1/DDX60/CXCL10/SKP2/ERCC6/IFITM3/LILRB1/AIM2/TICAM1/RELA/MX2/ELMOD2/EXOC1/SIN3A/TRIM22/IRF9/IFIT3/ISG20/HYAL2/AIMP1/TSPAN32/DDX58/ADARB1/TRAF3/OAS3/IFI27/RSAD2/IL1B/IFIT2/RNASE6/SAMHD1/DHX9/MMP12/PML/OAS2/ISG15/TRIM11/NLRP9/APOBEC3G/SLFN13/MAVS/IFI44L/IL6/APOBEC3C/IFIT5/LSM14A/PUM2/ILF3/DTX3L/ZC3HAV1/NPLOC4/IFIH1/SEC14L1/SERINC3/TARBP2/BCL2/ANKRD17/BIRC3/UNC13D/MX1/DDX1/ZMYND11/IFNK/RNASEL/HTRA1/IL12RB1/PCBP2/IFIT1/DDIT4/IRF2/ZMPSTE24/DMBT1/RTP4/EIF2AK2/C1QBP/CNOT7/MUL1/FADD/GPATCH3/PRF1/POLR3E/TLR8/RIOK3/APOBEC3B/HERC5/IFNG/TRIM15/NLRX1/TLR3/IFNAR2/IL12B/TRAF3IP1/TRIM6/EIF2AK4/MICA/POLR3F/NT5C3A/UNC93B1/RNF216/TSPAN6/ADAR/ZCCHC3/IL23A/POLR3K/EXOSC5	129
BP	GO:0051056	regulation of small GTPase mediated signal transduction	174/7096	338/18670	2.624e-07	2.455e-05	1.83e-05	IGF1/SH2B2/RTN4R/RAC2/SIPA1L1/ARF6/STMN1/LYN/FBP1/NOTCH2/CDC42SE1/ARHGEF18/ARHGAP31/STARD8/RASGEF1A/ARAP1/NUP62/RHOBTB1/PLEKHG2/SPATA13/CYTH4/MYO9B/TIMP2/BCL6/ARAP3/RHOC/ARHGEF3/KITLG/STARD13/FLOT1/DENND1A/ALS2/SQSTM1/P2RY8/JAK2/CYTH1/FGD6/FGD5/A2M/SHOC2/EPHB2/AKAP13/ARHGDIA/FAM13A/KRAS/APOE/ARHGEF10L/ARHGEF40/RDX/ARHGAP30/ARHGAP20/ARRB1/ARHGAP25/KCTD10/HEG1/NRG1/ARHGAP19/RHOG/ARFGEF1/STMN3/CDC42SE2/ITSN1/EPOR/ABR/NET1/ARHGDIB/RASA2/ARHGAP22/HRAS/ABL1/ARHGEF6/SRGAP3/OPHN1/ABCA1/GDI1/ARHGAP26/IQSEC1/RHOT2/GDI2/RASGRP1/ARHGEF2/RASAL3/SHC1/TAGAP/CRK/RAF1/FBXO8/SH3BP1/RAC1/ARHGAP24/MAPRE2/LPAR6/KALRN/OCRL/IRS2/FLCN/RHOU/STK19/ARHGAP6/BCR/ARHGAP12/RALGAPB/SRGAP2/RASA3/SCAI/NRP1/DNM2/RHOQ/TRIP10/KANK1/SIPA1L3/ARHGAP18/GPR18/SYNGAP1/RHOV/GRB2/OBSCN/RABGEF1/RHOF/CD2AP/ITGA3/LPAR1/SPRY1/F2R/RHOH/RASGRF1/GARNL3/VAV1/GMIP/ABL2/IQSEC2/PREX1/ITSN2/SLIT2/SPRY2/RALGPS1/RALBP1/GNA13/GPR35/APOA1/STAMBP/RASAL1/ARHGEF37/IQSEC3/FGD3/OGT/MAPKAP1/RALGAPA2/ARHGEF17/SYNPO2L/FGD4/PSD4/DENND4B/CHN2/RELN/EPS8L2/MAP4K4/SRGAP1/P2RY10/RHOA/MET/SIPA1L2/ARHGEF4/RHOBTB2/SYDE1/GPR20/ADCYAP1R1/MCF2L/ARFGAP1/MMD2/KIF14/ARHGEF9/PSD3/RASGRP4	174
BP	GO:0072524	pyridine-containing compound metabolic process	109/7096	195/18670	2.705e-07	2.494e-05	1.859e-05	IGF1/PNP/CBFA2T3/TALDO1/HK3/NAMPT/QPRT/BST1/LDHA/FBP1/PARP9/PGK1/MDH1/KCNAB2/STAT3/PFKFB3/NUP62/NUP160/PFKM/PTGS2/PFKP/GAPDH/NUP214/NMNAT3/SLC2A6/ME1/P2RX7/NUPR1/PGAM1/PKM/GALK1/RPE/EIF6/TPI1/ZBTB7A/TKT/NUP85/HIF1A/SEH1L/INSR/ALDOC/NUP43/RPIA/NMNAT1/ENO1/IDO1/ALDOA/PARP16/NADK2/POM121/MPC2/OGDH/IDH1/GPI/LDHB/G6PD/PFKFB4/PPARGC1A/IDH2/KYNU/HAAO/DHTKD1/SLC25A12/PGM2/PRKAG2/MYOG/NCOR1/PFKFB1/NUP88/HDAC4/MDH1B/DERA/NUP107/NMRK2/PDHB/FOXK2/NMNAT2/DDIT4/PGK2/PFKFB2/ARNT/PPARA/NUP93/IDO2/SLC5A8/PRKAA1/PSEN1/NUP205/ENO2/SLC4A1/NUP50/IFNG/PRKAG1/OGT/PGD/ESRRB/ZBTB20/VCP/ADPGK/ME2/APP/FMO2/AOX1/PFKL/NNT/POM121C/AAAS/PGLS/RBKS	109
BP	GO:0001776	leukocyte homeostasis	56/7096	86/18670	3.087e-07	2.784e-05	2.075e-05	SH2B2/SLC40A1/TSC22D3/CCR2/ANXA1/SKIL/BCL10/LYN/PMAIP1/SLC46A2/TNFAIP3/KITLG/MIF/P2RX7/SLC7A11/DOCK10/CD74/AXL/TGFB1/PPP3CB/HIF1A/TNFSF13B/CORO1A/TCIRG1/FLT3/PDE4B/CASP3/ABL1/HMGB1/IL6/BCL2L11/BCL2/BAX/PIK3CD/PPP2R3C/LGALS9/ADA/CXCR2/FADD/ADAM17/JAM3/DOCK11/TNFRSF13B/MERTK/SPTA1/BAP1/GAPT/TNFRSF13C/GPR183/FOXN1/BAK1/CACNA1F/CXCL6/LAT/MEF2C/PIK3CB	56
BP	GO:2001234	negative regulation of apoptotic signaling pathway	125/7096	230/18670	3.105e-07	2.784e-05	2.075e-05	IGF1/ITPRIP/FYN/PEA15/TRIM32/CX3CR1/CDKN2D/NR4A2/PINK1/GCLM/LMNA/SLC35F6/TMBIM6/GNAI3/PTGS2/TNFRSF10A/SH3RF1/STRADB/EYA3/TNFAIP3/BCL2A1/MIF/ACKR3/CD44/GSTP1/FAS/TNF/CD74/HMOX1/TMEM14A/PRELID1/CXCL12/RELA/CSNK2A2/HIGD1A/HGF/HIF1A/CTNNA1/WFS1/HSPB1/MAPK7/PCGF2/PTTG1IP/MNT/TMEM161A/NDUFS3/MCL1/MPV17L/HTRA2/FZD9/ENO1/TNFSF10/GCLC/CASP8/IL1B/ARHGEF2/PHIP/IL7/TRADD/CLU/RAF1/SIRT1/ELL3/SLC25A5/LRRK2/PLAUR/DDX3X/MUC1/VNN1/BMP5/TXNDC12/NRP1/PSME3/IVNS1ABP/MMP9/BCL2/GNAI2/BMP4/BAX/SERPINE1/HMGB2/NOC2L/CTH/IL1A/ZMYND11/CREB3/PDX1/UNC5B/VDAC2/RFFL/YBX3/CAAP1/NFE2L2/TNFRSF10B/BRCA1/FADD/RRM2B/COL2A1/TRAF2/ACAA2/ZC3HC1/PSEN1/MDM2/TCF7L2/EYA4/TAF9B/SNAI1/FAIM2/DNAJA1/HYOU1/MAZ/RB1/MAP2K5/TERT/GPX1/MEIS3/TRIAP1/CX3CL1/BAG5/FAIM/BCL2L2/ATAD5/SIAH2/FIGNL1/DDIAS	125
BP	GO:0031341	regulation of cell killing	62/7096	98/18670	3.421e-07	3.024e-05	2.255e-05	ITGAM/SERPINB9/CLEC7A/STX7/CD55/GAPDH/CD1C/PTPRC/P2RX7/CD1E/LAMP1/CD59/LILRB1/IL7R/CD226/PPP3CB/LEP/FAM49B/HLA-F/HLA-E/HLA-B/CLEC12B/AGER/RASGRP1/CD1B/PIK3R6/CRK/TYROBP/HLA-G/DNASE1/CD5L/HLA-C/BCL2L11/FCER2/PVR/LAG3/CD1D/IL12RB1/CD1A/LGALS9/PGLYRP4/ULBP2/CRTAM/VAV1/KIR2DL4/FADD/PRF1/AP1G1/BAD/HLA-A/HAVCR2/IFNG/NCR3/SERPINB4/HSP90AB1/IL12B/SH2D1A/MICA/NCR1/IL18RAP/IL23A/CXCL6	62
BP	GO:0038061	NIK/NF-kappaB signaling	103/7096	183/18670	3.634e-07	3.169e-05	2.363e-05	NOD2/TLR2/PSMB9/CUL1/NLRP3/TNFRSF10A/ZFP91/ADIPOR1/PSMB8/BIRC2/ACTN4/TRIP6/NLRP12/AKIP1/ALK/PSMA5/TNF/PSMD11/NFKBIA/PSME1/PPP4C/REL/RELA/IL18R1/NR3C2/PSMB10/PRDX1/PSMA1/PSMA4/TRAF6/NFKB2/TLR4/PTPN22/CARD14/RELB/PSMB1/IL1B/PSMC4/AGER/PSMD13/HMGB1/TRADD/PSMB3/RBCK1/BMP7/CHI3L1/CYLD/PSMB5/PSMD6/EDA/DICER1/PSMC3/SPHK1/HDAC7/PSME3/EDAR/PSMC6/BIRC3/AGO1/LGALS9/NFAT5/CALR/TNFRSF10B/EIF2AK2/EGFR/IL18/TRAF2/CPNE1/PSMC1/TREM2/PSMD8/HAVCR2/PSMA2/TLR3/CARD10/IL12B/PSMC5/PSMC2/PSMB2/PSMD4/COPS8/LIME1/RHOA/APP/LIMS1/PDCD4/TSPAN6/CCL19/MALT1/TIRAP/CHUK/TRAF4/PSMD1/PSMB4/HMGB4/NLRC3/IL23A/TLR6/PSMD9/C1QTNF3/PSMD3/SASH1/MIR146A	103
BP	GO:0019216	regulation of lipid metabolic process	205/7096	410/18670	3.943e-07	3.393e-05	2.53e-05	KLF4/FPR2/HTR2B/VDR/NOD2/ASAH1/SLC27A1/PDK4/ANXA1/PEX11A/APPL2/SOCS3/LYN/POR/STARD4/SOD1/ATP1A1/FLT1/CAPN2/NFYC/GPAM/THRA/PTGS2/NPC2/WDR91/PPARD/GOLM1/LSR/ADIPOR1/SIRT4/ABHD6/DDX20/PANK2/FBXW7/RDH10/SIK1/ATG14/WDR81/PLIN2/SLC45A3/APOC1/SCARB1/SQLE/ME1/PSAP/EGR1/TNF/CD74/ELOVL5/CISH/TNFRSF21/AKR1C3/NFKB1/RAN/IGFBP7/APOE/HMGCR/TXNRD1/LPGAT1/PIK3R3/PDK2/EIF6/CDK4/CPT2/TGFB1/SIN3A/HMGCS1/SCD/SOCS5/ENHO/CD36/PTK2B/LEP/NR1H2/ERLIN1/PRKCD/ACADM/HELZ2/PIK3IP1/FLT3/SOCS6/FGR/RGL1/BMP2/ABCA1/GSTZ1/IL1B/SAMD8/LAMTOR1/NR1D2/LDLR/ACOX1/CHD9/LMF1/ERLIN2/PIK3R6/FDPS/ACACB/P2RY12/CREB1/IDH1/SIRT1/CREBL2/DGAT2/SIN3B/FABP3/IRS2/SOCS7/PDGFB/G0S2/PPARGC1A/EPHA8/FGF1/ARV1/RAB38/MLYCD/GNB3/TM7SF2/APOA5/PTK2/BBS4/ARF1/CRTC3/ORMDL2/SPHK1/IDI1/PRKAG2/NCOR1/BMP5/RXRA/ORMDL3/MTMR4/SCAP/ID2/ABCG1/NR1H3/SC5D/PDK1/TYSND1/MTMR2/CPT1A/ABCB4/PDGFA/SREBF2/ACADVL/ZMPSTE24/STUB1/GLIPR1/EEF1A2/TGS1/NFE2L1/SERPINA12/INSIG1/PDP2/FABP5/BRCA1/PPARA/BCL11B/FHL2/ADIPOR2/PRKAA1/DNAJC15/MTMR3/APOA1/CYP27B1/SOCS1/PLA2G6/RBL2/RORA/SNAI1/ALAS1/IFNG/NR4A3/PDP1/MTMR9/RB1/PIK3CG/CARM1/TBL1X/EDF1/SLA2/ZBTB20/MTOR/MBTPS2/TAZ/SNCA/LACTB/ELOVL6/ABCD1/CCL19/LPCAT1/NRBF2/CCKBR/OPA3/SMPD2/MBTPS1/KPNB1/PDPR/CCR7/SOCS2/THRSP/NR1H4/TM6SF2/FAM3A/GRHL1	205
BP	GO:1903037	regulation of leukocyte cell-cell adhesion	158/7096	304/18670	4.274e-07	3.629e-05	2.706e-05	KLF4/IGF1/NOD2/PNP/CCR2/FYN/NFKBIZ/PTPN6/LILRB2/ANXA1/BCL10/LYN/CD55/IRF1/CSK/ARG2/GPNMB/EGR3/PTPN2/TNFRSF14/BCL6/NLRP3/SMAD7/DUSP10/FGL2/CD44/IL4R/CEBPB/CBFB/MAP3K8/PTPRC/IL15/HFE/ADAM8/TNF/CD74/TNFRSF21/LILRB1/CXCL12/DPP4/DUSP3/IL7R/RELA/DOCK8/TGFB1/CCDC88B/PTAFR/PAK1/SOCS5/LEP/TNFSF13B/FAM49B/CORO1A/LILRB4/TRAF6/ZBTB1/ITGA4/IL20RB/PTPN22/ZBTB7B/SOCS6/HLA-DPB1/HLA-DPA1/HLA-E/NCK1/DTX1/CD209/CASP3/IDO1/NFKBID/PAK2/IL1B/AIF1/SIRPB1/AGER/CCL5/RASGRP1/RASAL3/PIK3R6/HLA-DMB/ICOSLG/HMGB1/EFNB1/IGFBP2/IL7/IL6ST/TESPA1/HLA-G/RAC1/IL6/LCK/CYLD/FLOT2/CTLA4/GLMN/ETS1/TIGIT/VSIG4/SCGB1A1/VNN1/PDCD1LG2/NRARP/BMP4/CD47/LGALS1/LAG3/CD1D/IL12RB1/GRB2/CD300A/CD274/LGALS9/LAX1/NFAT5/EBI3/ICOS/BTN2A2/HES1/ADA/HLX/VAV1/IL18/PPARA/FADD/AP3B1/CD276/TFRC/TNFSF4/SART1/PAG1/SOCS1/SIRPG/BAD/HAVCR2/IFNG/SKAP1/SPTA1/NR4A3/CD5/CD4/TNFRSF13C/IL12B/PRKCZ/CD80/TBX21/PRKCQ/RHOA/CD83/CCL19/MALT1/ZBTB16/CCR7/CD3E/PDCD1/TWSG1/CD24/IL23A/MIR146A	158
BP	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	52/7096	79/18670	4.884e-07	4.093e-05	3.052e-05	FCGR1B/FCGR1A/PSMB9/ITGB5/PSMB8/TAP2/TAP1/SEC22B/PSMA5/PSMD11/PDIA3/PSME1/PSMB10/CD36/PSMA1/PSMA4/NCF4/HLA-F/NCF2/IKBKG/NCF1/HLA-E/HLA-B/VAMP3/PSMB1/PSMC4/PSMD13/PSMB3/HLA-G/TAPBP/HLA-C/PSMB5/PSMD6/PSMC3/PSME3/PSMC6/CYBA/CYBB/CALR/PSMC1/PSMD8/HLA-A/PSMA2/PSMC5/PSMC2/PSMB2/PSMD4/CHUK/PSMD1/PSMB4/PSMD9/PSMD3	52
BP	GO:0050777	negative regulation of immune response	87/7096	150/18670	5.027e-07	4.124e-05	3.075e-05	CCR2/PTPN6/IL27RA/ANXA1/SERPINB9/GRN/LYN/CD55/ARG2/STAT6/PTPN2/TNFRSF14/BCL6/SMAD7/DUSP10/TNFAIP3/NLRC5/FGL2/IL4R/PTPRC/A2M/HFE/CD59/TNF/IRAK3/YTHDF3/HMOX1/LILRB1/IL7R/NMI/TGFB1/PPP3CB/SOCS5/PSMA1/NR1H2/METTL3/HLA-F/IL20RB/ZBTB7B/ABR/HLA-E/CACTIN/CLEC12B/SAMHD1/MMP12/CRK/HLA-G/SERPING1/CR1/CTLA4/BCR/VSIG4/RPS19/CD96/PARP3/NR1H3/CD300A/LGALS9/PGLYRP4/FER/RABGEF1/AMBP/HLX/CNOT7/MUL1/KIR2DL4/TNFSF4/IL13RA2/APOA1/CD84/TGFB3/HAVCR2/SERPINB4/NLRX1/IL12B/MICA/GPX1/TBX21/TYRO3/ADAR/TRAFD1/FOXF1/PDCD1/PSMB4/NLRC3/SLAMF8/FAM3A	87
BP	GO:0045619	regulation of lymphocyte differentiation	96/7096	169/18670	5.048e-07	4.124e-05	3.075e-05	PNP/CCR2/NFKBIZ/PTPN6/LILRB2/ANXA1/IRF1/SOD1/EGR3/PTPN2/SOX13/RNF41/BCL6/NLRP3/SH3RF1/SMAD7/SLC46A2/DUSP10/CD2/FGL2/IL4R/CBFB/PTPRC/IL15/ADAM8/CD74/PRELID1/IL7R/AXL/TGFB1/SOCS5/METTL3/LILRB4/ZBTB1/FLT3LG/ZBTB7B/DTX1/ABL1/NFKBID/RASGRP1/CLPTM1/PIK3R6/HMGB1/IL7/TNFRSF18/TESPA1/HLA-G/TOX/CYLD/CR1/CTLA4/VNN1/NRARP/BMP4/CYP26B1/NFATC2/ID2/LAG3/PPP2R3C/INHBA/IL12RB1/LGALS9/PGLYRP4/BTN2A2/MMP14/ADA/HLX/IL18/AP3B1/TNFSF4/NFAM1/SART1/KAT2A/SOCS1/BAD/ZFP36L2/IFNG/FANCD2/PCID2/INHA/IL12B/DROSHA/PRKCZ/CD80/TBX21/RHOA/FOXN1/FANCA/CD83/CCL19/IKZF3/MALT1/ZBTB16/SLAMF8/IL23A/HLA-DOA	96
BP	GO:0009166	nucleotide catabolic process	102/7096	182/18670	5.45e-07	4.397e-05	3.278e-05	IGF1/PNP/CBFA2T3/HK3/UPP1/LDHA/FBP1/PGK1/STAT3/PFKFB3/NUP62/NUP160/PFKM/PFKP/GAPDH/NUP214/ACOT7/SLC2A6/P2RX7/NUPR1/PGAM1/PKM/GALK1/EIF6/TPI1/HDDC3/ZBTB7A/NEIL2/NUP85/HIF1A/UNG/NUDT1/SEH1L/NT5C/INSR/ALDOC/NUP43/PDE4B/ENO1/ALDOA/HINT1/SAMHD1/POM121/OGDH/NUDT9/GPI/TDG/PFKFB4/PPARGC1A/MLYCD/DNPH1/DHTKD1/SLC25A12/PRKAG2/MYOG/NCOR1/NUDT3/PFKFB1/NUP88/HDAC4/PDE7A/DERA/NUP107/FOXK2/DDIT4/PGK2/PFKFB2/ADA/ARNT/NUDT7/PPARA/NUP93/PRKAA1/PSEN1/NUP205/ENO2/SLC4A1/NUP50/IFNG/PRKAG1/OGT/CNP/ESRRB/ZBTB20/GPX1/DCTPP1/VCP/ADPGK/PDE8A/APP/NT5M/UPP2/AMPD3/ABCD1/DUT/NUDT16/PFKL/MBD4/POM121C/PDE8B/AAAS/SMUG1	102
BP	GO:0050670	regulation of lymphocyte proliferation	114/7096	208/18670	5.731e-07	4.566e-05	3.404e-05	IGF1/PNP/CCR2/RAC2/PTPN6/LILRB2/ANXA1/CDKN1A/BST1/LYN/CD55/IRF1/ARG2/GPNMB/MNDA/LST1/TNFRSF14/BCL6/SH3RF1/CD40/MIF/CEBPB/PTPRC/IL15/CD74/TNFRSF21/CD320/LILRB1/TICAM1/CD22/TGFB1/CCDC88B/LEP/TNFSF13B/CORO1A/TRAF6/CLC/FLT3LG/IL20RB/TLR4/PTPN22/ZBTB7B/HLA-DPB1/HLA-DPA1/HLA-E/NCK1/CD209/CASP3/SLC39A10/IDO1/IL1B/AIF1/AGER/CCL5/RASAL3/AHR/HLA-DMB/ICOSLG/HMGB1/EFNB1/IGFBP2/IL7/TYROBP/IL6ST/HLA-G/IL6/IRS2/CTLA4/GLMN/ATM/VSIG4/SCGB1A1/PDCD1LG2/BCL2/BMP4/NFATC2/CLCF1/CD1D/IL12RB1/CD300A/CD274/LGALS9/EBI3/BTN2A2/HES1/ADA/IL18/FADD/CD276/TFRC/TNFRSF13B/TNFSF4/CHRNB2/TNFRSF4/HAVCR2/SPTA1/TNFSF18/CD4/TNFRSF13C/IL12B/CD80/PRKCQ/GPR183/CCL19/IKZF3/TIRAP/TNFSF8/CD3E/ATAD5/TWSG1/CD24/IL23A/MEF2C/ZNF335	114
BP	GO:0050671	positive regulation of lymphocyte proliferation	77/7096	130/18670	7.105e-07	5.592e-05	4.169e-05	IGF1/PNP/CCR2/LILRB2/ANXA1/CDKN1A/BST1/CD55/BCL6/CD40/MIF/PTPRC/IL15/CD74/CD320/TICAM1/CCDC88B/LEP/TNFSF13B/CORO1A/TRAF6/FLT3LG/TLR4/HLA-DPB1/HLA-DPA1/HLA-E/NCK1/CD209/SLC39A10/IL1B/AIF1/AGER/CCL5/RASAL3/HLA-DMB/ICOSLG/HMGB1/EFNB1/IGFBP2/IL7/IL6ST/IL6/IRS2/PDCD1LG2/BCL2/NFATC2/CLCF1/CD1D/IL12RB1/CD274/LGALS9/EBI3/HES1/ADA/IL18/FADD/CD276/TFRC/TNFSF4/CHRNB2/TNFRSF4/HAVCR2/SPTA1/CD4/TNFRSF13C/IL12B/CD80/PRKCQ/GPR183/CCL19/TIRAP/CD3E/ATAD5/CD24/IL23A/MEF2C/ZNF335	77
BP	GO:0097191	extrinsic apoptotic signaling pathway	121/7096	224/18670	7.29e-07	5.669e-05	4.226e-05	SRPX/IGF1/ITPRIP/FYN/PEA15/SKIL/BCL10/GCLM/LMNA/BLOC1S2/DEDD/RNF41/TNFRSF10A/SH3RF1/STRADB/PMAIP1/EYA3/TNFAIP3/BCL2A1/KITLG/CIB1/JAK2/GSTP1/PTPRC/FAS/P2RX7/TNF/HMOX1/PDIA3/GSK3B/TMC8/RELA/TGFB1/HGF/CTNNA1/MAPK7/FEM1B/HYAL2/MCL1/HTRA2/IFI27/PARP2/TNFRSF10C/TNFRSF12A/CASP3/SP100/TNFSF10/GCLC/CASP8/PAK2/IL1B/DEDD2/ARHGEF2/DAPK1/PML/PHIP/IL7/TRADD/RAF1/RBCK1/ACVR1B/G0S2/CYLD/DCC/DDX3X/WWOX/BCL2L11/BMP5/NRP1/PSME3/BCL2/BMP4/BAX/SERPINE1/HMGB2/CRADD/CASP2/IL1A/ZMYND11/INHBA/MLLT11/UNC5B/RFFL/KRT8/HIPK1/TRAF1/TNFRSF10B/PPP1CA/PPP2R1B/BRCA1/FADD/COL2A1/TRAF2/ZC3HC1/DEPTOR/TCF7L2/SIVA1/EYA4/BAD/MKNK2/IFNG/FAIM2/MOAP1/RET/ZSWIM2/TLR3/MAP2K5/DBH/DIABLO/TERT/GPX1/CX3CL1/BAK1/FAIM/BCL2L2/APPL1/BMPR1B/DAXX/ERBB3/SIAH2/FOXO3	121
BP	GO:0032944	regulation of mononuclear cell proliferation	114/7096	209/18670	7.919e-07	6.085e-05	4.536e-05	IGF1/PNP/CCR2/RAC2/PTPN6/LILRB2/ANXA1/CDKN1A/BST1/LYN/CD55/IRF1/ARG2/GPNMB/MNDA/LST1/TNFRSF14/BCL6/SH3RF1/CD40/MIF/CEBPB/PTPRC/IL15/CD74/TNFRSF21/CD320/LILRB1/TICAM1/CD22/TGFB1/CCDC88B/LEP/TNFSF13B/CORO1A/TRAF6/CLC/FLT3LG/IL20RB/TLR4/PTPN22/ZBTB7B/HLA-DPB1/HLA-DPA1/HLA-E/NCK1/CD209/CASP3/SLC39A10/IDO1/IL1B/AIF1/AGER/CCL5/RASAL3/AHR/HLA-DMB/ICOSLG/HMGB1/EFNB1/IGFBP2/IL7/TYROBP/IL6ST/HLA-G/IL6/IRS2/CTLA4/GLMN/ATM/VSIG4/SCGB1A1/PDCD1LG2/BCL2/BMP4/NFATC2/CLCF1/CD1D/IL12RB1/CD300A/CD274/LGALS9/EBI3/BTN2A2/HES1/ADA/IL18/FADD/CD276/TFRC/TNFRSF13B/TNFSF4/CHRNB2/TNFRSF4/HAVCR2/SPTA1/TNFSF18/CD4/TNFRSF13C/IL12B/CD80/PRKCQ/GPR183/CCL19/IKZF3/TIRAP/TNFSF8/CD3E/ATAD5/TWSG1/CD24/IL23A/MEF2C/ZNF335	114
BP	GO:1901657	glycosyl compound metabolic process	85/7096	147/18670	8.086e-07	6.11e-05	4.555e-05	FUCA1/TYMP/PNP/UPP1/CBR4/AKR1B1/GNAI3/ACPP/AHCY/AKR1C3/RAN/AK3/AKR7A2/NFS1/MPP1/HDDC3/GMPS/DGUOK/RAB23/APIP/NT5C/TYW3/AKR1A1/ADK/MBIP/CDADC1/GUK1/IMPDH1/AKR1C1/CTPS2/MTRR/DPYD/LCMT2/ENOPH1/CMPK1/TK1/MOCS2/APOBEC3G/MACROD1/GLA/PRTFDC1/LRRK2/APOBEC3C/DNPH1/NME3/GUSB/MTAP/APOBEC2/NME4/GTPBP1/GMPR2/ATIC/RHOQ/NME1/DERA/NAGA/PRPS1/GAMT/PPAT/MOCS3/ADA/DCK/AHCYL2/AKR1B10/AHCYL1/UCK1/TK2/APOBEC3B/PRPS1L1/FUCA2/CTPS1/CAD/PRPS2/CDA/RHOA/UCKL1/NT5C3A/ENPP4/NT5M/UPP2/AMPD3/ADAL/GIMAP7/ABHD10/OARD1	85
BP	GO:0002698	negative regulation of immune effector process	72/7096	120/18670	8.142e-07	6.11e-05	4.555e-05	CCR2/PTPN6/ANXA1/SERPINB9/GRN/CD55/TMBIM6/BCL6/SMAD7/DUSP10/FGL2/IL4R/PTPRC/A2M/HFE/CD59/TNF/IRAK3/HMOX1/LILRB1/CD22/IL7R/TGFB1/PPP3CB/SOCS5/HLA-F/IL20RB/ZBTB7B/ABR/HLA-E/CLEC12B/CRK/HLA-G/SERPING1/CR1/BCR/VSIG4/RPS19/CD96/NPLOC4/SEC14L1/TARBP2/PARP3/CD47/HTRA1/PCBP2/CD300A/LGALS9/PGLYRP4/FER/RABGEF1/HLX/C1QBP/MUL1/KIR2DL4/GPATCH3/TNFSF4/RIOK3/IL13RA2/APOA1/CD84/TGFB3/HAVCR2/SERPINB4/NLRX1/TRAF3IP1/MICA/TBX21/TSPAN6/FOXF1/APPL1/SLAMF8	72
BP	GO:0031331	positive regulation of cellular catabolic process	182/7096	361/18670	8.697e-07	6.452e-05	4.81e-05	IGF1/CBFA2T3/EZR/TMTC3/PINK1/ZFP36/TSC1/C9orf72/PFKFB3/TPCN1/GNAI3/SMAD7/TNFAIP3/TOB1/KEAP1/DDRGK1/FBXW7/DHRSX/CTSC/RNF139/AGO2/P2RX7/BCAP31/ADAM8/TNF/YTHDF3/HMOX1/MOV10/NUPR1/HNRNPR/METTL14/TRIM13/GIGYF2/APOE/GSK3B/MAGEF1/BTG2/RNF19B/FBXL5/TICAM1/EDEM1/SH3BP4/CDC37/RDX/SGTA/HIF1A/TRIM22/ZFAND2A/SOCS5/PTK2B/CSNK1D/PRKCD/PTTG1IP/INSR/METTL3/TFEB/RNF217/IKBKG/TP53INP2/CEBPA/SPTLC2/PLK2/ANKIB1/GCLC/RAB3GAP1/IL1B/PSMC4/FURIN/UQCC2/LDLR/DAPK1/ZC3H12D/LRP1/HMGB1/CLU/SIRT1/GPSM1/IL6/IRS2/SNX33/EDEM2/LRRK2/PFKFB4/FLCN/SUMO1/APOA5/PTK2/HSPBP1/ATM/CSNK1A1/CSNK1E/RNFT1/DTX3L/ZC3HAV1/ARIH2/BCL2L11/PLK3/KAT5/FTO/VPS13D/EPM2A/DISC1/TRIM21/UBQLN2/GTPBP1/PFKFB1/MEFV/BAX/TRIB2/ADRB2/BBS7/DET1/TNRC6B/CPT1A/NKD2/ST20/TNRC6A/HNRNPD/CPEB3/KLHL40/PFKFB2/ARNT/STUB1/NFE2L2/ATXN3/ULK1/CNOT7/MUL1/PPARA/CAV3/MID2/BAG2/SESN1/ADAM9/DVL1/PRKAA1/PSEN1/FMR1/MDM2/SH3GLB1/SUPV3L1/SMCR8/NPRL2/MSN/PSMC1/BAD/ZFP36L2/TREM2/DXO/IFNG/TRIM65/RNF185/CLEC16A/LACRT/OPTN/MTDH/ESRRB/EIF2AK4/PSMC2/ZBTB20/VCP/AURKA/APP/PIM2/SNCA/SNX9/RBX1/ABCD1/PNPT1/KCNE2/CHFR/ROCK2/ENDOG/NNT/HMGB4/SESN2/PACSIN3/FOXO3/PLEKHN1/UPF1/PIK3CB/MAPK9	182
BP	GO:0045824	negative regulation of innate immune response	41/7096	59/18670	9.113e-07	6.606e-05	4.925e-05	SERPINB9/GRN/PTPN2/DUSP10/TNFAIP3/NLRC5/A2M/IRAK3/YTHDF3/LILRB1/NMI/NR1H2/METTL3/HLA-F/HLA-E/CACTIN/CLEC12B/SAMHD1/MMP12/CRK/HLA-G/SERPING1/CR1/VSIG4/RPS19/CD96/NR1H3/LGALS9/CNOT7/MUL1/KIR2DL4/HAVCR2/SERPINB4/NLRX1/MICA/TYRO3/ADAR/TRAFD1/NLRC3/SLAMF8/FAM3A	41
BP	GO:0002456	T cell mediated immunity	65/7096	106/18670	9.291e-07	6.606e-05	4.925e-05	MYO1G/CCR2/STX7/CD55/SLC11A1/NLRP3/SMAD7/CD1C/CTSC/PTPRC/P2RX7/CD1E/HFE/LILRB1/IL7R/DENND1B/PPP3CB/IL18R1/FAM49B/HLA-F/TRAF6/ZBTB1/CLC/IL20RB/HLA-E/HLA-B/RSAD2/IL1B/FBXO38/AGER/CD1B/HMGB1/TRPM4/IL1R1/HLA-G/IL6/HLA-C/BTN3A2/EMP2/BTN3A3/PVR/CD1D/IL12RB1/CD1A/FZD5/GZMM/ULBP2/IL18/FADD/TRAF2/PRF1/TNFSF4/HLA-A/SCART1/IL12B/MICA/PRKCZ/TBX21/IL18RAP/MALT1/CD8A/WAS/RAB27A/IL23A/RFTN1	65
BP	GO:0002711	positive regulation of T cell mediated immunity	35/7096	48/18670	9.398e-07	6.606e-05	4.925e-05	STX7/NLRP3/CD1C/PTPRC/P2RX7/CD1E/IL18R1/FAM49B/HLA-F/TRAF6/ZBTB1/HLA-E/HLA-B/RSAD2/IL1B/FBXO38/CD1B/IL1R1/HLA-G/IL6/HLA-C/PVR/CD1D/IL12RB1/CD1A/FZD5/IL18/FADD/TRAF2/TNFSF4/HLA-A/IL12B/PRKCZ/MALT1/IL23A	35
BP	GO:0002831	regulation of response to biotic stimulus	81/7096	139/18670	9.425e-07	6.606e-05	4.925e-05	GRN/CD55/PARP9/ARG2/SYT11/TNFAIP3/MIF/BIRC2/FGL2/LY96/LY86/STAT1/LILRA2/IL15/DDX60/ERCC6/LILRB1/AIM2/CD226/ELMOD2/SIN3A/UNC13B/CD36/TRAF6/MAPKBP1/TSPAN32/DDX58/TRAF3/CACTIN/IL1B/FBXO38/DHX9/MMP12/HMGB1/APOBEC3G/MAVS/SIGLEC16/PUM2/DTX3L/NPLOC4/SEC14L1/TARBP2/ANKRD17/SIGLEC11/BIRC3/PVR/PPP2R3C/HTRA1/IL12RB1/PCBP2/CD274/CYBA/IFIT1/ZMPSTE24/CRTAM/C1QBP/MUL1/GPATCH3/RIOK3/HERC5/SIGIRR/HAVCR2/HRG/TRIM15/NLRX1/LACRT/IL12B/OPTN/TRAF3IP1/TRIM6/EIF2AK4/FOXP1/CX3CL1/RNF216/TSPAN6/ZCCHC3/PRKCA/IL23A/FAM3A/CXCL6/SASH1	81
BP	GO:0050715	positive regulation of cytokine secretion	81/7096	139/18670	9.425e-07	6.606e-05	4.925e-05	HTR2B/NOD2/CLEC5A/TLR1/TLR2/PTGER4/WNT5A/CD58/IL17RA/FCN1/LILRA5/GAPDH/TNFRSF14/NLRP3/CLEC4E/MBP/MIF/CD2/LILRA2/IL4R/NLRP12/RGCC/P2RX7/TNF/IL1RAP/AIM2/TRIM16/FFAR2/FRMD8/PANX1/HYAL2/TLR4/DDX58/PTPN22/FGR/ABL1/IL1B/AIF1/AGER/RASGRP1/DHX9/MMP12/LRP1/HMGB1/SPTBN1/MAVS/LRRK2/GLMN/ALOX15B/IFIH1/IL1A/CASP1/OSM/CD274/LGALS9/FZD5/F2R/CRTAM/IFNGR1/TLR8/NLRP1/HAVCR2/TSLP/IFNG/MAPK11/CD34/NLRP2/TRIM6/PRKCZ/CSF1R/SCAMP5/TRPV4/CCL19/CHUK/CD244/IL26/HMGB4/IL17RB/C1QTNF3/IL17RC/IGHD	81
BP	GO:0070498	interleukin-1-mediated signaling pathway	62/7096	100/18670	9.566e-07	6.606e-05	4.925e-05	MYD88/NOD2/IL1R2/TNIP2/PSMB9/CUL1/PSMB8/SQSTM1/MAP3K8/EGR1/UBE2N/PSMA5/PSMD11/IRAK3/NFKBIA/VRK2/NFKB1/IL1RAP/PSME1/RELA/IRAK4/PSMB10/PSMA1/PSMA4/TAB3/TRAF6/IKBKG/PSMB1/IL1B/PSMC4/PSMD13/PSMB3/IL1RN/IL1R1/IL6/PSMB5/PSMD6/OTUD4/PSMC3/TAB1/PSME3/PSMC6/TOLLIP/IL1A/UBC/PLCB1/PSMC1/PSMD8/PSMA2/ST18/PSMC5/PSMC2/PSMB2/PSMD4/RBX1/CHUK/PSMD1/PSMB4/PELI2/PSMD9/PSMD3/MIR146A	62
BP	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	60/7096	96/18670	9.643e-07	6.606e-05	4.925e-05	FCGR1B/FCGR1A/PSMB9/ITGB5/PSMB8/TAP2/TAP1/SEC22B/BCAP31/PSMA5/HFE/PSMD11/PDIA3/PSME1/SAR1B/PSMB10/CD36/PSMA1/PSMA4/NCF4/HLA-F/NCF2/IKBKG/NCF1/HLA-E/HLA-B/VAMP3/PSMB1/PSMC4/PSMD13/PSMB3/HLA-G/TAPBPL/TAPBP/HLA-C/PSMB5/PSMD6/PSMC3/PSME3/PSMC6/CYBA/CYBB/CANX/CALR/PSMC1/ERAP1/PSMD8/HLA-A/PSMA2/ERAP2/PSMC5/PSMC2/PSMB2/PSMD4/CHUK/PSMD1/PSMB4/SEC24A/PSMD9/PSMD3	60
BP	GO:1901292	nucleoside phosphate catabolic process	104/7096	188/18670	9.822e-07	6.606e-05	4.925e-05	IGF1/PNP/CBFA2T3/HK3/UPP1/LDHA/FBP1/PGK1/STAT3/PFKFB3/NUP62/NUP160/PFKM/PFKP/GAPDH/NUP214/ACOT7/SLC2A6/P2RX7/NUPR1/SMPDL3A/PGAM1/PKM/GALK1/EIF6/TPI1/HDDC3/ZBTB7A/NEIL2/NUP85/HIF1A/UNG/NUDT1/SEH1L/NT5C/INSR/ALDOC/NUP43/PDE4B/ENO1/ALDOA/HINT1/SAMHD1/POM121/OGDH/NUDT9/GPI/TDG/PFKFB4/PPARGC1A/MLYCD/DNPH1/DHTKD1/SLC25A12/PRKAG2/MYOG/NCOR1/NUDT3/PFKFB1/NUP88/HDAC4/PDE7A/DERA/NUDT5/NUP107/FOXK2/DDIT4/PGK2/PFKFB2/ADA/ARNT/NUDT7/PPARA/NUP93/PRKAA1/PSEN1/NUP205/ENO2/SLC4A1/NUP50/IFNG/PRKAG1/OGT/CNP/ESRRB/ZBTB20/GPX1/DCTPP1/VCP/ADPGK/PDE8A/APP/NT5M/UPP2/AMPD3/ABCD1/DUT/NUDT16/PFKL/MBD4/POM121C/PDE8B/AAAS/SMUG1	104
BP	GO:0001818	negative regulation of cytokine production	153/7096	296/18670	9.892e-07	6.606e-05	4.925e-05	KLF4/IGF1/KLF2/FN1/CX3CR1/EZR/PTGER4/PTPN6/IL27RA/DLL1/ACP5/ANXA1/IL1R2/APPL2/ZFP36/SLC11A1/CSK/GBP1/ARG2/GPNMB/SYT11/LILRA5/BCL6/NLRP3/SMAD7/TNFAIP3/BANK1/NLRC5/LGR4/NLRP12/RGCC/GSTP1/PTPRC/HFE/TNF/IRAK3/HMOX1/TNFRSF21/NFKB1/LILRB1/SLAMF1/REL/AXL/NDRG2/NMI/TGFB1/CHID1/HGF/ARRB1/SOCS5/SERPINB1/HLA-F/MAPKBP1/IL20RB/TLR4/DDX58/PTPN22/CACTIN/UBE2L6/RELB/CMKLR1/IDO1/C5orf30/HOMER3/FURIN/AGER/PML/ISG15/HMGB1/TYROBP/NPTN/RAC1/MAVS/ADCY7/IL6/CYLD/CD200R1/TIGIT/VSIG4/DICER1/SCGB1A1/PDCD1LG2/CD96/AKAP8/NPLOC4/IFIH1/KAT5/HDAC7/MEFV/OTUD5/YY1/TRIB2/LAG3/FFAR4/GPR18/INHBA/PCBP2/CD274/LGALS9/PGLYRP4/RABGEF1/BTN2A2/CD2AP/CPTP/LAPTM4B/C1QBP/MUL1/PPP1R11/GPATCH3/TNFSF4/TAX1BP1/TLR8/SRGN/MERTK/HERC5/SIGIRR/APOA1/TREM2/TNFRSF4/CD84/TGFB3/HAVCR2/IFNG/PIN1/CD34/NLRX1/HSP90AB1/INHA/MAP2K5/LBP/IL12B/TRAF3IP1/CD33/ASB1/TBX21/NAV3/CDH3/C5AR2/CX3CL1/RNF216/CD83/PDCD4/ABCD1/NR1H4/NLRC3/TWSG1/CD24/IL23A/TLR6/C1QTNF3/RNF135/GHRL/MIR146A	153
BP	GO:0051047	positive regulation of secretion	211/7096	428/18670	9.928e-07	6.606e-05	4.925e-05	IGF1/S100A8/ITGAM/HTR2B/NOD2/CLEC5A/TLR1/EZR/STAM/TLR2/KCNN4/RAB9A/PTGER4/ARF6/PINK1/WNT5A/RETN/ATP6AP1/CD58/IL17RA/FCN1/LILRA5/GAPDH/TNFRSF14/SPP1/NLRP3/CLEC4E/PPARD/MBP/MIF/CD2/WLS/LILRA2/IL4R/NLRP12/RGCC/STXBP5/JAK2/P2RX7/HFE/ADAM8/LAMP1/TNF/IL1RAP/AIM2/CXCL12/TRIM16/TGFB1/PPP3CB/EXOC1/STXBP1/AACS/UNC13B/ARRB1/HIF1A/PTAFR/FFAR2/FRMD8/PANX1/LEP/HLA-F/HYAL2/MCU/AIMP1/TLR4/DDX58/PTPN22/ITSN1/FGR/HLA-E/CDK5/ABL1/RAB3GAP1/IL1B/DTNBP1/AIF1/AGER/RASGRP1/DHX9/C2CD2L/SDCBP/MMP12/MPC2/LRP1/HMGB1/TNFRSF11A/CREB1/TRPM4/DOC2B/GPI/RAC1/GLUD1/SPTBN1/MAVS/IL6/IRS2/LRRK2/GLMN/SERP1/SRI/ARF1/OXCT1/ALOX15B/IFIH1/ADORA2B/RPH3AL/GOLPH3L/GNAI2/CHMP2A/GPR27/TSG101/ABCG1/UNC13D/RAB5A/IL1A/CASP1/SYTL4/OSM/INHBA/HGS/CD274/PDX1/LGALS9/CYBA/TM7SF3/HYAL3/VPS4B/FZD5/CD2AP/PFKFB2/F2R/DNM1L/CRTAM/CDK5R2/CLASP2/IFNGR1/RAB8B/EGFR/NMB/SCIN/ADAM9/TNFSF4/GIPR/AP1G1/TLR8/RAB3A/GALR1/CHRNB2/TCF7L2/SNX5/BAD/SYT9/TREM2/PLA2G6/TNFRSF4/SYTL2/FRMD4A/TGFB3/NLRP1/HAVCR2/TSLP/IFNG/VIP/MAPK11/SYT1/KIF5B/CD34/LACRT/INHA/SNX4/NLRP2/TRIM6/SYT4/CD33/PRKCZ/OPRL1/CADPS2/CSF1R/SCAMP5/TRPV4/GHRH/RAB3D/SNCA/SOX4/CCL19/CHUK/CD244/GCG/NLGN2/IL26/GJA1/CACNA1H/SEC24A/HMGB4/IL17RB/NR1H4/TARDBP/UCN3/RAB27A/RBP4/PSMD9/C1QTNF3/P2RY1/IL17RC/TACR2/NTSR1/GHRL/IGHD/KISS1/APLN/PHPT1	211
BP	GO:0050708	regulation of protein secretion	230/7096	472/18670	1.01e-06	6.65e-05	4.958e-05	IGF1/HTR2B/NOD2/CLEC5A/FN1/TLR1/EZR/TLR2/KCNN4/PTGER4/IL27RA/ANXA1/IL1R2/RHBDF2/ARF6/LYN/WNT5A/GBP1/ARG2/DISP1/SYT11/ERP29/CD58/IL17RA/TMBIM6/FCN1/DPH3/LILRA5/GAPDH/TNFRSF14/NLRP3/CLEC4E/PPARD/HADH/TNFAIP3/BANK1/CD40/MBP/MIF/SIRT4/CD2/WLS/LGR4/ENY2/LILRA2/PER2/IL4R/NLRP12/RGCC/JAK2/FAM3D/P2RX7/ADAM8/TNF/TNFRSF21/IL1RAP/APOE/HMGCR/LILRB1/AIM2/DPP4/LRP5/CD22/TRIM16/TGFB1/PPP3CB/EXOC1/ITPR1/AACS/UNC13B/ARRB1/HIF1A/FFAR2/PIM3/ENHO/FRMD8/TLR5/PANX1/LEP/SERPINB1/TRAF6/MAPKBP1/HYAL2/MCU/TCIRG1/TLR4/DDX58/PTPN22/FGR/HLA-E/ABL1/RSAD2/IL1B/AIF1/UQCC2/AGER/CCL5/RASGRP1/DHX9/C2CD2L/RAP1A/MMP12/PML/MPC2/LRP1/HMGB1/RFX3/TRPM4/DOC2B/GPI/RAC1/GLUD1/SPTBN1/MAVS/IL6/IRS2/SLC25A5/LRRK2/CD200R1/DNAJC1/KLF7/IDH2/GLMN/SERP1/SRI/ARF1/OXCT1/ALOX15B/PAM/IFIH1/RPH3AL/GOLPH3L/GPR27/ABCG1/NR1H3/IL1A/SLC16A1/FFAR4/CASP1/SYTL4/OSM/TLR10/CPT1A/CD274/PDX1/RHBDD3/LGALS9/TM7SF3/RABGEF1/BTN2A2/FZD5/CD2AP/CPTP/PFKFB2/F2R/DNM1L/HMGN3/CRTAM/IFNGR1/EGFR/ICA1/PPP1R11/TRAF2/CLOCK/ADAM9/TNFSF4/GIPR/TLR8/SRGN/TCF7L2/APOA1/SOCS1/BAD/SYT9/TREM2/PLA2G6/TNFRSF4/FRMD4A/TGFB3/NLRP1/HAVCR2/TSLP/IFNG/ARNTL/MAPK11/KIF5B/CD34/NLRP2/TRIM6/SYT4/CD33/PRKCZ/CSF1R/NDUFAF2/MAP4K4/SCAMP5/FOXP1/TRPV4/C5AR2/CX3CL1/SLC9B2/SOX4/CCL19/SIDT2/CHUK/CD244/ARL2BP/GCG/CCR7/PFKL/NLGN2/IL26/GJA1/SEC24A/HMGB4/IL17RB/NR1H4/TARDBP/STXBP4/PRKCA/UCN3/RBP4/TLR6/PSMD9/C1QTNF3/IL17RC/GHRL/IGHD/PHPT1/RHBDF1	230
BP	GO:0002791	regulation of peptide secretion	242/7096	500/18670	1.034e-06	6.73e-05	5.018e-05	CRHBP/IGF1/S100A8/HTR2B/NOD2/CLEC5A/FN1/TLR1/EZR/TLR2/KCNN4/PTGER4/IL27RA/ANXA1/IL1R2/RHBDF2/ARF6/LYN/WNT5A/GBP1/ARG2/DISP1/SYT11/ERP29/CD58/IL17RA/TMBIM6/FCN1/DPH3/LILRA5/GAPDH/TNFRSF14/NLRP3/CLEC4E/PPARD/HADH/TNFAIP3/BANK1/CD40/MBP/MIF/SIRT4/CD2/WLS/LGR4/ENY2/LILRA2/PER2/IL4R/NLRP12/RGCC/JAK2/FAM3D/P2RX7/HFE/ADAM8/TNF/CD74/TNFRSF21/IL1RAP/APOE/HMGCR/LILRB1/AIM2/DPP4/LRP5/CD22/TRIM16/TGFB1/PPP3CB/EXOC1/ITPR1/AACS/UNC13B/ARRB1/HIF1A/FFAR2/PIM3/ENHO/FRMD8/TLR5/PANX1/LEP/SERPINB1/TRAF6/MAPKBP1/HYAL2/MCU/AIMP1/TCIRG1/TLR4/DDX58/PTPN22/ITSN1/FGR/HLA-E/ABL1/RSAD2/PAX8/IL1B/AIF1/UQCC2/AGER/CCL5/RASGRP1/DHX9/C2CD2L/RAP1A/MMP12/PML/MPC2/LRP1/HMGB1/RFX3/TRPM4/DOC2B/GPI/RAC1/GLUD1/SPTBN1/MAVS/IL6/KALRN/IRS2/SLC25A5/LRRK2/CD200R1/DNAJC1/KLF7/IDH2/GLMN/SERP1/SRI/ARF1/OXCT1/ALOX15B/PAM/IFIH1/RPH3AL/GOLPH3L/GPR27/ABCG1/NR1H3/IL1A/SLC16A1/FFAR4/CASP1/SYTL4/OSM/TLR10/CPT1A/CD274/PDX1/RHBDD3/LGALS9/TM7SF3/RABGEF1/BTN2A2/FZD5/CD2AP/CPTP/PFKFB2/F2R/DNM1L/HMGN3/CRTAM/IFNGR1/RAB8B/EGFR/ICA1/PPP1R11/TRAF2/CLOCK/ADAM9/TNFSF4/GIPR/TLR8/SRGN/TCF7L2/APOA1/SOCS1/BAD/SYT9/TREM2/PLA2G6/TNFRSF4/FRMD4A/TGFB3/NLRP1/HAVCR2/TSLP/IFNG/ARNTL/MAPK11/KIF5B/CD34/NLRP2/TRIM6/SYT4/CD33/PRKCZ/CSF1R/NDUFAF2/MAP4K4/SCAMP5/FOXP1/TRPV4/C5AR2/GHRH/CX3CL1/SLC9B2/SOX4/CCL19/SIDT2/CHUK/CD244/ARL2BP/GCG/CCR7/PFKL/NLGN2/IL26/GJA1/SEC24A/HMGB4/IL17RB/NR1H4/TARDBP/STXBP4/PRKCA/UCN3/RBP4/TLR6/PSMD9/C1QTNF3/IL17RC/GHRL/IGHD/KISS1/APLN/PHPT1/RHBDF1	242
BP	GO:0032496	response to lipopolysaccharide	168/7096	330/18670	1.043e-06	6.73e-05	5.018e-05	S100A8/JUNB/FOS/NOD2/CX3CR1/TLR2/PTGER4/LILRB2/ACP5/GCH1/BCL10/SBNO2/LYN/CD55/ZFP36/SLC11A1/TNIP2/WNT5A/PTGER2/VIM/HCK/JUND/CAPN2/PTGS2/NLRP3/PPARD/TFPI/DUSP10/TNFAIP3/RPS6KA3/MIF/LY96/LY86/PPBP/LILRA2/ADH5/CXCL9/CEBPB/SCARB1/MGST2/JAK2/GSTP1/CXCL11/IFNAR1/P2RX7/TNF/IRAK3/PAF1/NFKBIA/CXCL10/NFKB1/LILRB1/PLAA/TICAM1/MIR142/MAPKAPK3/RELA/AXL/CDK4/TGFB1/CSF2RB/ALAD/PTAFR/HPGD/CD36/NR1H2/TRAF6/NFKB2/CXCL13/TLR4/PTPN22/ABR/PDE4B/CASP3/CACTIN/ABL1/NFKBIB/IDO1/CASP8/ABCA1/IL1B/CCL5/PLCG2/HMGB1/CMPK2/THBD/TNFRSF11A/IL1RN/IL6/PPARGC1A/CCR5/TIMP4/SPARC/BCR/SCGB1A1/PDCD1LG2/HDAC2/CD96/AKAP8/MGST1/CYP1A2/MAPK8/MAPKAPK2/SERPINE1/HMGB2/OTUD5/HNRNPA0/NR1H3/SGMS1/TNIP3/CASP1/PRPF8/CD274/LGALS9/FER/CNR2/F2R/IRF8/IL18/ADAM17/ATP2A2/MAOB/ADAM9/TNFSF4/HAMP/MAPK1/SIGIRR/CYP27B1/TREM2/SRR/HAVCR2/PALM3/BDKRB1/GNG12/LACRT/CTSG/CNP/REN/LBP/WDR35/IL12B/MTDH/TRIM6/CD80/HDAC5/FOXP1/PLSCR4/RHOA/CDC73/SNCA/CX3CL1/PDCD4/MALT1/TIRAP/CHUK/CCR7/AKIRIN2/MPO/GJA1/NR1H4/PRKCA/CXCL6/MEF2C/UPF1/SASH1/S100A14/IL37/MIR146A	168
BP	GO:0032946	positive regulation of mononuclear cell proliferation	77/7096	131/18670	1.085e-06	6.932e-05	5.168e-05	IGF1/PNP/CCR2/LILRB2/ANXA1/CDKN1A/BST1/CD55/BCL6/CD40/MIF/PTPRC/IL15/CD74/CD320/TICAM1/CCDC88B/LEP/TNFSF13B/CORO1A/TRAF6/FLT3LG/TLR4/HLA-DPB1/HLA-DPA1/HLA-E/NCK1/CD209/SLC39A10/IL1B/AIF1/AGER/CCL5/RASAL3/HLA-DMB/ICOSLG/HMGB1/EFNB1/IGFBP2/IL7/IL6ST/IL6/IRS2/PDCD1LG2/BCL2/NFATC2/CLCF1/CD1D/IL12RB1/CD274/LGALS9/EBI3/HES1/ADA/IL18/FADD/CD276/TFRC/TNFSF4/CHRNB2/TNFRSF4/HAVCR2/SPTA1/CD4/TNFRSF13C/IL12B/CD80/PRKCQ/GPR183/CCL19/TIRAP/CD3E/ATAD5/CD24/IL23A/MEF2C/ZNF335	77
BP	GO:0009141	nucleoside triphosphate metabolic process	182/7096	362/18670	1.097e-06	6.942e-05	5.175e-05	IGF1/CBFA2T3/HK3/LDHA/PINK1/FBP1/PGK1/VPS9D1/STAT3/PFKFB3/NUP62/NUP160/PFKM/UQCRC2/GNAI3/PFKP/GAPDH/SLC25A25/NUP214/SLC2A6/P2RX7/UQCR11/NDUFA8/NUPR1/SMPDL3A/RAN/AK3/PGAM1/AK2/PKM/GALK1/NFS1/EIF6/TPI1/ZBTB7A/NDUFC1/TGFB1/DGUOK/RAB23/NUP85/CLPX/HIF1A/NUDT1/ISCU/SEH1L/NDUFB11/ADK/INSR/ALDOC/MBIP/NDUFS3/GUK1/NUP43/IMPDH1/NDUFA3/CTPS2/NMNAT1/ATP6V1A/ENO1/DNAJC30/ALDOA/AK8/UQCC2/NDUFA11/PARG/SAMHD1/CMPK1/POM121/OGDH/CMPK2/CHCHD10/MOCS2/UQCR10/COX7C/GPI/ATP6V1B2/LRRK2/PFKFB4/PPARGC1A/FLCN/COX7A2L/DHTKD1/NME3/NDUFA4/SLC25A12/SHMT2/LDHC/NME4/PRKAG2/MYOG/NCOR1/COX4I2/NDUFA1/GTPBP1/PFKFB1/NUP88/HDAC4/ATP1B1/RHOQ/NME1/NUDT5/TEFM/COQ9/NUP107/COA6/COX15/TYMS/NDUFA10/FOXK2/NDUFB1/DDIT4/NDUFB5/UQCRQ/PGK2/PFKFB2/MOCS3/ADA/ARNT/DNM1L/NDUFS1/UCK1/SLC25A33/PPARA/NUP93/TBPL1/SLC25A13/RRM2B/NDUFB8/PRKAA1/PSEN1/DNAJC15/NUP205/ENO2/PID1/SURF1/NDUFB6/BAD/SLC4A1/TREM2/CTPS1/CAD/NUP50/IFNG/PRKAG1/OGT/ATP7A/NDUFB3/SDHA/ESRRB/ZBTB20/DCTPP1/VCP/NDUFS7/ADPGK/NDUFV2/ND4/SDHD/RHOA/UCKL1/TAZ/APP/SNCA/UQCRB/ATP6V1B1/AMPD3/ABCD1/NDUFB2/SDHAF2/GIMAP7/MYH3/COX6C/DUT/ATP1A2/NUDT16/PFKL/CTNS/NDUFS2/POM121C/AAAS/FIGNL1/NDUFA7/COX7B	182
BP	GO:0006650	glycerophospholipid metabolic process	163/7096	319/18670	1.122e-06	7.033e-05	5.243e-05	FPR2/HTR2B/LPCAT2/SLC27A1/CDS1/PLA2G12A/SOCS3/HADHB/ENPP2/CHPT1/DGKA/CAPN2/GPAM/ABHD4/PLSCR1/PLEKHA1/MBOAT7/GDE1/MTMR12/ABHD6/ABHD12/GPCPD1/PIGV/CDS2/PIGP/APOC1/SCARB1/PTDSS2/PLA2G7/MBOAT1/IMPAD1/PTPMT1/PLBD1/CISH/PIGK/CETP/INPP1/LPGAT1/PIK3R3/PTPN13/PNPLA6/PLD1/PNPLA3/SACM1L/CSNK2A2/PIGN/STARD10/IP6K1/SOCS5/SYNJ1/PITPNM1/PLA1A/NAPEPLD/DDHD1/TTC7A/SOCS6/SERINC1/FIG4/FAM126A/AGPAT3/PAFAH1B1/PLA2G15/PLCG2/LDLR/PLB1/PIK3R6/CSNK2B/PIGF/SYNJ2/STARD7/CDIPT/FABP3/PIGB/DPM1/OCRL/SOCS7/PDGFB/ABHD3/AGPAT4/GPAA1/SH3YL1/RAB38/ALDH5A1/APOA5/PNPLA8/ATM/ARF1/CRLS1/PIGM/MFSD2A/PLA2G3/PLEKHA8/MBOAT2/SBF1/LCAT/SERINC3/MTMR4/TMEM86B/MPPE1/INPP5K/IMPA2/MTMR6/PIK3CD/PRDX6/PI4K2A/RAB5A/PIGQ/ACP6/MTMR2/INPP5F/PLEK/PDGFA/FAR1/PIGO/HADHA/CHKA/PIGH/PLCB1/FABP5/AGK/AGPAT5/DBI/PLD2/PLCD4/CPNE1/DPM3/MTMR3/PLEKHA3/APOA1/SOCS1/PLA2G6/PIGT/GNPAT/CPNE3/MTMR9/SLC44A2/PIK3CG/SLA2/SERAC1/CSF1R/AGPAT1/PIP5K1B/CHAT/TAZ/VAC14/ABHD16A/LPCAT1/CHKB/PGS1/AGPAT2/SOCS2/SERINC2/PGAP3/INPPL1/NR1H4/ARF3/EFR3A/PGAP1/INPP5A/PIK3CB/IMPA1/PI4KB/LPCAT3	163
BP	GO:0046651	lymphocyte proliferation	142/7096	272/18670	1.16e-06	7.198e-05	5.367e-05	IGF1/PNP/CCR2/FYN/RAC2/PTPN6/LILRB2/ANXA1/CDKN1A/BST1/ELF4/LYN/CD55/SLC11A1/IRF1/ARG2/GPNMB/MNDA/LST1/CCND3/TNFRSF14/BCL6/SH3RF1/CD40/MIF/CEBPB/PTPRC/IL15/P2RX7/CD74/TNFRSF21/CD320/LILRB1/TICAM1/CD22/IL7R/DOCK8/TGFB1/PPP3CB/CCDC88B/PSMB10/LEP/TNFSF13B/PRKCD/CORO1A/TRAF6/CLC/FLT3LG/IL20RB/TLR4/PTPN22/FLT3/ZBTB7B/IMPDH1/HLA-DPB1/HLA-DPA1/HLA-E/NCK1/CD209/CASP3/ABL1/SLC39A10/PURA/IDO1/IL1B/CD151/AIF1/AGER/CCL5/RASAL3/AHR/HLA-DMB/ICOSLG/HMGB1/EFNB1/IGFBP2/IL7/TYROBP/IL6ST/HLA-G/IL6/IRS2/CTLA4/GLMN/ATM/VSIG4/AZI2/SCGB1A1/PDCD1LG2/BCL2/BMP4/BAX/NFATC2/MS4A1/CLCF1/IFNK/CR2/CD1D/IL12RB1/CD300A/CD274/LGALS9/EBI3/BTN2A2/HES1/ADA/IL18/FADD/CD276/TFRC/TNFRSF13B/TNFSF4/BTN3A1/CHRNB2/MSN/TNFRSF4/HAVCR2/CTPS1/PLCL2/SPTA1/TNFSF18/CD4/PIK3CG/GAPT/TNFRSF13C/IL12B/CD80/PRKCQ/GPR183/CCL19/IKZF3/MALT1/TIRAP/TNFSF8/CD3E/ATAD5/GJA1/TWSG1/CD24/IL23A/MEF2C/ZNF335	142
BP	GO:0042108	positive regulation of cytokine biosynthetic process	45/7096	67/18670	1.22e-06	7.501e-05	5.592e-05	CCR2/TLR1/CLEC7A/BCL10/IRF1/WNT5A/AZU1/STAT3/CEBPG/JAK2/PTPRC/EGR1/TNF/CD74/HMOX1/TICAM1/RELA/PTAFR/HSPB1/TRAF6/TLR4/IL1B/AGER/TYROBP/IL6/GLMN/MAPKAPK2/IL1A/EBI3/CYBB/CD276/PSEN1/TLR8/IFNG/CD4/TLR3/LBP/TNFRSF13C/IL12B/CD80/PRKCQ/APP/TIRAP/CD3E/TLR6	45
BP	GO:1901224	positive regulation of NIK/NF-kappaB signaling	50/7096	77/18670	1.488e-06	8.916e-05	6.647e-05	NOD2/TLR2/TNFRSF10A/ZFP91/ACTN4/TRIP6/NLRP12/TNF/RELA/IL18R1/NR3C2/TRAF6/TLR4/CARD14/IL1B/AGER/HMGB1/TRADD/RBCK1/CHI3L1/EDA/SPHK1/EDAR/AGO1/LGALS9/NFAT5/CALR/TNFRSF10B/EIF2AK2/EGFR/IL18/TRAF2/TREM2/HAVCR2/TLR3/CARD10/IL12B/COPS8/RHOA/APP/LIMS1/PDCD4/CCL19/MALT1/TIRAP/TRAF4/HMGB4/IL23A/TLR6/SASH1	50
BP	GO:0001909	leukocyte mediated cytotoxicity	65/7096	107/18670	1.492e-06	8.916e-05	6.647e-05	ITGAM/PTPN6/SERPINB9/STX7/AZU1/CD1C/CEBPG/CTSC/PTPRC/P2RX7/CD1E/LAMP1/LILRB1/IL7R/CD226/PPP3CB/STXBP2/PRDX1/LEP/FAM49B/HLA-F/CORO1A/HLA-E/HLA-B/CLEC12B/AGER/RASGRP1/CD1B/PIK3R6/CRK/TYROBP/HLA-G/DNASE1/HLA-C/EMP2/GZMB/UNC13D/PVR/LAG3/CD1D/IL12RB1/CD1A/LGALS9/GZMM/ULBP2/CRTAM/VAV1/KIR2DL4/IL18/FADD/PRF1/AP1G1/HLA-A/HAVCR2/NCR3/SERPINB4/CTSG/IL12B/SH2D1A/MICA/NCR1/IL18RAP/RAB27A/IL23A/CXCL6	65
BP	GO:0043254	regulation of protein complex assembly	227/7096	467/18670	1.492e-06	8.916e-05	6.647e-05	MYADM/CDC42EP4/VASP/BMF/PTGER4/CLEC7A/ARF6/STMN1/PINK1/DR1/HCK/RHOBTB1/PLEKHG2/THRA/PMAIP1/FBLIM1/RHOC/BIRC2/G3BP2/TMSB10/TNF/SENP6/SPIRE1/GBP5/IQGAP2/APOE/ERCC4/GSK3B/ACTR2/BBS10/AIM2/TMOD3/VPS41/KIF9/TMC8/HCLS1/EVL/LDLRAD4/PSRC1/TWF2/TGFB1/RDX/STXBP1/ZNF451/PFN1/CDC42EP2/UNC13B/SAR1B/PAK1/CD36/CLIP1/PTK2B/CAPZA2/RPA1/PRKCD/SRF/LATS1/GMFG/CORO1A/BAIAP2/CXCL13/ARFGEF1/DDB1/TLR4/CAPG/NCK1/VEGFA/ABL1/FCHSD1/CDK5RAP2/ABCA1/PMEPA1/PSMC4/ARPC1A/ARHGEF2/CAPZA1/MITF/P2RY12/ANKRD27/MAPRE1/HMGB1/SUB1/CREB1/CLU/RAF1/TPPP3/MKKS/RAC1/ARPIN/SPTBN1/TTBK1/ARPC1B/CDC42EP3/CDH5/CYFIP1/MYO1C/ATXN2/TAL1/SUMO1/LCMT1/CORO1B/DDX3X/SAR1A/ATM/BBS4/ARF1/SETX/GTF2H4/PSMC3/ATXN2L/FNIP1/ARPC5L/LCP1/BCL2L11/LCAT/COTL1/MEFV/VPS18/NAPA/CAND1/AVIL/BAX/PSMC6/ERCC1/CDKN1B/MMP3/KANK1/TRIOBP/ARHGAP18/ADD3/RANGRF/GRB2/PLEK/VDAC2/JMY/MMP1/ACTR3B/FER/DMTN/CPTP/SLC39A12/STUB1/DNM1L/ACTR3/IMPACT/MED25/INSIG1/LMOD3/EIF2AK2/PEX14/ULK1/ATR/CAV3/SCIN/CDH17/PREX1/MPP7/HEY2/SLIT2/CCL26/TUBB4A/FSCN1/PRKAA1/DNAJC15/RIOK3/RAB3A/DDB2/SH3GLB1/MSN/ERCC2/EIF4G1/NCLN/ARPC4/HNF1B/BCLAF1/FOSL1/IFNG/HNF1A/SKAP1/SPTA1/HRG/RNF4/SLAIN2/CUL4B/OPRD1/RB1/SPTBN2/PPP2R5B/PSMC5/VPS16/ARPC2/TRAF3IP1/KANK3/PSMC2/PRKCZ/VCP/MTOR/NAV3/RHOA/PICK1/SNCA/CLIP3/IAPP/SNX9/RBX1/MET/ASAP1/CCR7/WAS/PAXIP1/ICE1/RHOBTB2/WNT10B/CCL24/PREB/NLRC3/SPIDR/TPPP/TLR6/BIN1/KIF14/NCKAP1/FCHSD2/ALB/TAF7/MAPK9/FMN1	227
BP	GO:0070663	regulation of leukocyte proliferation	119/7096	222/18670	1.507e-06	8.921e-05	6.65e-05	IGF1/PNP/CCR2/RAC2/PTPN6/LILRB2/ANXA1/CDKN1A/BST1/LYN/CD55/IRF1/ARG2/GPNMB/MNDA/LST1/TNFRSF14/BCL6/SH3RF1/TNFAIP3/CD40/KITLG/MIF/CEBPB/GSTP1/PTPRC/IL15/CD74/TNFRSF21/CD320/LILRB1/TICAM1/CD22/TGFB1/CCDC88B/LEP/TNFSF13B/CORO1A/TRAF6/CLC/FLT3LG/IL20RB/TLR4/PTPN22/ZBTB7B/HLA-DPB1/HLA-DPA1/HLA-E/NCK1/CD209/CASP3/SLC39A10/IDO1/IL1B/AIF1/AGER/CCL5/RASAL3/AHR/HLA-DMB/ICOSLG/HMGB1/EFNB1/IGFBP2/IL7/TYROBP/IL6ST/HLA-G/IL6/IRS2/CTLA4/GLMN/ATM/VSIG4/SCGB1A1/PDCD1LG2/BCL2/CCL8/BMP4/NFATC2/CLCF1/CD1D/IL12RB1/CD300A/CD274/LGALS9/EBI3/BTN2A2/HES1/ADA/IL18/FADD/CD276/TFRC/TNFRSF13B/TNFSF4/CHRNB2/TNFRSF4/HAVCR2/SPTA1/TNFSF18/CD4/TNFRSF13C/IL12B/CD80/PRKCQ/GPR183/CCL19/IKZF3/TIRAP/TNFSF8/CD3E/ATAD5/GREM1/TWSG1/CD24/IL23A/MEF2C/ZNF335	119
BP	GO:0032615	interleukin-12 production	39/7096	56/18670	1.541e-06	9.039e-05	6.739e-05	TLR2/ACP5/CLEC7A/IRF1/LILRA5/CD40/IRAK3/NFKB1/LILRB1/SLAMF1/RELA/CD36/LEP/PRKCD/TRAF6/TLR4/CMKLR1/IDO1/AGER/HMGB1/HLA-G/TIGIT/MEFV/CD47/LGALS9/PLCB1/IRF8/C1QBP/TNFSF4/TLR8/IFNG/MAPK11/TLR3/IL12B/FOXP1/CCL19/TIRAP/CCR7/IL23A	39
BP	GO:0060337	type I interferon signaling pathway	59/7096	95/18670	1.605e-06	9.13e-05	6.806e-05	MYD88/PTPN6/GBP2/IRF7/IRF1/WNT5A/PTPN2/NLRC5/PSMB8/XAF1/STAT1/OASL/IFNAR1/IFITM2/EGR1/IFITM1/YTHDF3/IFITM3/CDC37/MX2/UBE2K/IFI35/IRF9/IFIT3/ISG20/METTL3/HLA-F/OAS3/IFI27/HLA-E/HLA-B/CACTIN/SP100/RSAD2/IFIT2/SAMHD1/MMP12/OAS2/ISG15/HLA-G/MAVS/LSM14A/HLA-C/TYK2/MX1/RNASEL/ZBP1/IFIT1/IRF2/IRF8/CNOT7/MUL1/FADD/HLA-A/JAK1/HSP90AB1/IFNAR2/TRIM6/ADAR	59
BP	GO:0071357	cellular response to type I interferon	59/7096	95/18670	1.605e-06	9.13e-05	6.806e-05	MYD88/PTPN6/GBP2/IRF7/IRF1/WNT5A/PTPN2/NLRC5/PSMB8/XAF1/STAT1/OASL/IFNAR1/IFITM2/EGR1/IFITM1/YTHDF3/IFITM3/CDC37/MX2/UBE2K/IFI35/IRF9/IFIT3/ISG20/METTL3/HLA-F/OAS3/IFI27/HLA-E/HLA-B/CACTIN/SP100/RSAD2/IFIT2/SAMHD1/MMP12/OAS2/ISG15/HLA-G/MAVS/LSM14A/HLA-C/TYK2/MX1/RNASEL/ZBP1/IFIT1/IRF2/IRF8/CNOT7/MUL1/FADD/HLA-A/JAK1/HSP90AB1/IFNAR2/TRIM6/ADAR	59
BP	GO:0043087	regulation of GTPase activity	232/7096	479/18670	1.607e-06	9.13e-05	6.806e-05	S100A10/HTR2B/RTN4R/SIPA1L1/TBC1D24/CDC42SE1/WNT5A/TSC1/ARHGAP31/SOD1/STARD8/VPS9D1/ARAP1/RASGRP2/MYO9B/BCL6/NEDD9/ARAP3/S1PR1/CD40/ALDH1A1/ADPRH/STARD13/RGS2/RASGRP3/DENND1A/ALS2/RABGAP1L/AGFG1/F11R/RGS1/STXBP5/TBC1D15/FGD6/FGD5/DVL2/EZH2/DOCK10/ARHGDIA/RAPGEF6/FAM13A/IQGAP2/GSK3B/ARHGEF10L/ASAP2/ARHGAP27/TBC1D5/PLXNB2/DENND1B/SH3BP4/DOCK8/ELMOD2/RDX/ARHGAP30/CDC42EP2/ARHGAP20/ARRB1/ARHGAP25/TRAPPC6A/GNAQ/RAPGEF2/PTK2B/SGSM1/PLXNC1/TBC1D1/ARHGAP19/RHOG/CXCL13/ARFGEF1/STMN3/SNX18/ADRB1/ABR/NET1/ARHGDIB/RASA2/ARHGAP22/HRAS/ARHGEF6/PAFAH1B1/SRGAP3/OPHN1/RGS12/RAB3GAP1/ARFGAP3/GDI1/RP2/ARHGAP26/IQSEC1/CCL5/GDI2/RASGRP1/RIN2/RAP1A/RASAL3/SEMA4D/TBC1D2/ANKRD27/TAGAP/RABGAP1/NPRL3/CRK/CCL7/MKKS/TBCK/SH3BP1/AGAP4/GPSM1/ARHGAP24/MAPRE2/RGL3/KALRN/OCRL/LRRK2/PDE6D/FLCN/DOCK5/TBC1D12/PTK2/ARHGAP6/BCR/ARHGAP12/BBS4/RALGAPB/RGS3/SRGAP2/RASA3/PLXNA1/CCL13/TBC1D17/TRAPPC6B/SBF1/NRP1/PLXND1/TBC1D9B/CCL8/TBC1D20/TBC1D13/BCAS3/RGS14/TBC1D8/SIPA1L3/ARHGAP18/ELMOD3/NDEL1/ACAP1/SNX13/SYNGAP1/TBC1D8B/RGS5/TBC1D7/EIF5/PTPRN2/TBC1D22A/ZC3H15/SPRY1/CORO1C/F2R/DNM1L/RHOH/RASGRF1/GARNL3/PLCB1/RABEP1/VAV1/GMIP/RCC2/CCL20/DOCK11/PREX1/SLIT2/CCL26/SPRY2/RALBP1/RUNDC1/NPRL2/RASAL1/ADAP1/TBC1D21/RGS20/FGD3/NUP50/PLXNA3/EVI5/LLGL1/PIN1/TBC1D10C/RALGAPA2/RIN1/ACAP3/AGAP3/PLXNA2/FGD4/RGS6/AGAP1/ALS2CL/CHN2/MAP4K4/SRGAP1/MTOR/PRTN3/GPS1/SBF2/LIMS1/CX3CL1/ACAP2/DEPDC5/CHM/ITGB1BP1/SNX9/GRTP1/RGS16/GRHL3/CCL19/SIPA1L2/RGP1/ADAP2/CCL4/ASAP1/RGS17/CCR7/PICALM/CCL24/SYDE1/PREB/ASAP3/SMAP2/ARFGAP1/TBC1D10B/CPEB2/FZD10/NTRK2	232
BP	GO:0032602	chemokine production	56/7096	89/18670	1.613e-06	9.13e-05	6.806e-05	KLF4/S100A9/S100A8/TRIM32/TLR2/CLEC7A/WNT5A/AZU1/ARG2/MBP/MIF/IL4R/GSTP1/EGR1/TNF/CD74/HMOX1/TICAM1/HIF1A/FFAR2/SOCS5/TLR4/IL1B/AIF1/AGER/LRP1/IL7/MAVS/IL6/DDX3X/ALOX15B/ADORA2B/MEFV/LGALS9/MCOLN2/EIF2AK2/MUL1/IL18/ADAM17/TNFSF4/SIGIRR/TREM2/HAVCR2/TSLP/IFNG/TLR3/MAP2K5/LBP/CSF1R/FOXP1/TRPV4/APP/TIRAP/NR1H4/C1QTNF3/CXCL6	56
BP	GO:0032103	positive regulation of response to external stimulus	164/7096	323/18670	1.716e-06	9.518e-05	7.096e-05	MYD88/S100A9/S100A8/FPR2/NOD2/S100A12/CCR2/TLR2/PTGER4/RAC2/NFKBIZ/CLEC7A/GRN/FABP4/OXSR1/WNT5A/AZU1/IL17RA/VEGFB/PTGS2/LILRA5/CAMK1D/S1PR1/MIF/LY96/LY86/CTSC/LGMN/NLRP12/CEBPB/MGST2/PLA2G7/JAK2/IL15/ADAM8/TNF/DDX60/CD74/NFKBIA/GPRC5B/CXCL10/NUPR1/GBP5/CXCL12/TICAM1/MIR142/TGFB1/UNC13B/FFAR2/MEGF8/HSPB1/PTK2B/SWAP70/MAPK13/TRAF6/HYAL2/NAPEPLD/CXCL13/TLR4/CEBPA/HLA-E/VEGFA/CMKLR1/IDO1/IL1B/AIF1/AGER/CCL5/LDLR/DHX9/P2RY12/LRP1/HMGB1/THBD/TNFRSF11A/TRADD/CCL7/PPM1F/IL6ST/RAC1/TTBK1/SIGLEC16/IL6/PDGFB/LRRK2/IL16/PUM2/ETS1/RPS19/C3AR1/MOSPD2/GPSM3/NRP1/ADORA2B/ZNF580/TMEM102/PRKD2/TNIP1/TGM2/C2CD4B/ANKRD17/SERPINE1/CD47/CCR6/ITGA2/NDEL1/OSM/CREB3/TLR10/CCR4/LGALS9/CYBA/SEMA5A/LPAR1/CALR/CNTF/C1QBP/EGFR/CXCR2/IL18/ADAM17/CLOCK/SLIT2/CCL26/TNFSF4/CYP27B1/TREM2/IL17B/HAVCR2/TSLP/HRG/TRIM15/SUCNR1/TLR3/PIK3CG/SNX4/LBP/F3/IL12B/OPTN/TRPV4/DAPK2/SNCA/CX3CL1/PDCD4/CCL19/MET/TIRAP/CCL4/CCR7/APPL1/ZCCHC3/CCL24/IL17RB/PRKCA/IL23A/SERPINF2/TLR6/IL17RC/PDGFD/GHRL/SASH1/S100A14/BMPR2	164
BP	GO:0007249	I-kappaB kinase/NF-kappaB signaling	140/7096	269/18670	1.719e-06	9.518e-05	7.096e-05	MYD88/HTR2B/NOD2/S100A12/FYN/TRIM32/CX3CR1/TLR2/BCL10/PINK1/TNIP2/DDX21/WNT5A/NUP62/FLNA/TNFAIP3/RHOC/CD40/DDRGK1/BIRC2/WLS/LY96/STAT1/SQSTM1/NLRP12/SHISA5/GSTP1/UBE2N/TNF/CD74/NFKBIA/HMOX1/AKAP13/GPRC5B/NKIRAS1/TRIM13/TICAM1/REL/RELA/IRAK4/NKIRAS2/TRIM22/HSPB1/CD36/TLE1/TAB3/TRAF6/MAPKBP1/IKBKG/TLR4/PLK2/RELB/ABL1/TNFSF10/NFKBID/CASP8/IL1B/S100B/MIER1/S100A4/ATP2C1/TIFAB/TRADD/RBCK1/IL1RN/SIRT1/MAVS/TIAF1/S100A13/IFIT5/SNIP1/EDA/AZI2/APOL3/ZDHHC13/TAB1/ASH1L/EDAR/TNIP1/TGM2/ANKRD17/CTH/BIRC3/ROR1/TNIP3/LGALS1/DDX1/CASP1/ZMYND11/ALPK1/UBC/LGALS9/LPAR1/F2R/SLC20A1/RHOH/TNFRSF10B/MUL1/USP10/GOLT1B/SECTM1/FADD/MID2/TRAF2/CPNE1/TLR8/RIOK3/TMED4/TIFA/TRAF5/CAPN3/RORA/UBE2I/SLC44A2/CD4/NLRX1/TLR3/OPTN/MTDH/LIME1/RHOA/PIM2/CX3CL1/TSPAN6/ZFAND6/CCL19/MALT1/TIRAP/CHUK/FAIM/CCR7/ROCK2/PELI2/GJA1/NR1H4/NLRC3/TLR6/AVPR2/CXXC5/IL37	140
BP	GO:0022407	regulation of cell-cell adhesion	199/7096	403/18670	1.735e-06	9.518e-05	7.096e-05	KLF4/IGF1/MYADM/NOD2/PNP/CCR2/FYN/NFKBIZ/PTPN6/LILRB2/ANXA1/BCL10/LYN/MAD2L2/CD55/IRF1/WNT5A/CELSR2/CSK/ARG2/GPNMB/EGR3/PTPN2/TNFRSF14/BCL6/NLRP3/SMAD7/DUSP10/MBP/FGL2/FLOT1/CD44/ADAM19/IL4R/CEBPB/RGCC/CBFB/JAK2/MAP3K8/PTPRC/IL15/HFE/ADAM8/TNF/CD74/TNFRSF21/FXYD5/LILRB1/CXCL12/DPP4/DUSP3/IL7R/RELA/DOCK8/TGFB1/RDX/CCDC88B/KIFAP3/GTPBP4/PTAFR/PAK1/SOCS5/MAPK7/LEP/TNFSF13B/SWAP70/PRKCD/METTL3/FAM49B/CORO1A/LILRB4/TRAF6/ZBTB1/CXCL13/ITGA4/IL20RB/PTPN22/ZBTB7B/SOCS6/HLA-DPB1/HLA-DPA1/BMP2/HLA-E/NCK1/VEGFA/DTX1/CD209/CASP3/ABL1/IDO1/NFKBID/PAK2/IL1B/AIF1/SIRPB1/AGER/CCL5/RASGRP1/RASAL3/PIK3R6/HLA-DMB/ICOSLG/HMGB1/EFNB1/IGFBP2/IL7/IL1RN/PPM1F/IL6ST/BMP7/TESPA1/HLA-G/RAC1/IL6/LCK/CYLD/FLOT2/CITED2/MDGA1/CTLA4/GLMN/PTK2/ETS1/TIGIT/VSIG4/AKNA/SCGB1A1/VNN1/PDCD1LG2/NRARP/ZNF703/BMP4/CD47/LGALS1/LAG3/CD1D/IL12RB1/GRB2/CD300A/CD274/LGALS9/LAX1/NFAT5/EBI3/ICOS/BTN2A2/DMTN/HES1/ADA/HLX/CDSN/VAV1/IL18/PPARA/FADD/AP3B1/CD276/TFRC/TNFSF4/WNT1/SART1/PAG1/APOA1/SOCS1/SIRPG/BAD/MYO10/HAVCR2/IFNG/SKAP1/SPTA1/NR4A3/CD5/GCNT2/CD4/MAP2K5/TNFRSF13C/IL12B/PRKCZ/CD80/TBX21/PRKCQ/DENND6A/RHOA/TRPV4/CX3CL1/CD83/CCL19/MALT1/ZBTB16/CCR7/CD3E/PDCD1/PRKCA/TWSG1/CD24/IL23A/SERPINF2/MIR146A	199
BP	GO:0019318	hexose metabolic process	131/7096	249/18670	1.74e-06	9.518e-05	7.096e-05	FUCA1/IGF1/HK3/PDK4/FBP1/PGK1/MDH1/AKR1B1/PTPN2/PFKFB3/PFKM/PFKP/GAPDH/PPARD/GALM/PMAIP1/ADIPOR1/ALDH1A1/SIK1/SLC45A3/COX11/PER2/SLC37A4/GALE/FUT4/TNF/GSK3B/FUT7/KAT2B/PGAM1/ATF4/LRP5/PKM/PDK2/DYRK2/GALK1/TPI1/MAN2A2/IGFBP4/MAN2B1/PCK2/LEP/PPP1R3E/AKR1A1/INSR/PPP1R3D/ALDOC/DDB1/ENO1/OMA1/ALDOA/PMM2/SLC25A10/SLC35B4/ACACB/CRTC2/SIRT1/NISCH/GPI/DGAT2/IRS2/G6PD/PFKFB4/FPGT/DUSP12/PPARGC1A/ALDH5A1/MLYCD/NLN/GNB3/LCMT1/SERP1/CREM/SLC25A12/PGM2/PGM5/KHK/PFKFB1/INPP5K/PPP1R3B/PDK1/PPP1R3F/CPT1A/PDX1/PDHB/FUT6/GALT/FOXK2/SORD/GOT2/PGK2/PFKFB2/ZMPSTE24/DLAT/NFE2L1/SERPINA12/PPP1CA/MST1/FABP5/PPARA/SLC25A13/KAT2A/PRKAA1/PDHA2/ENO2/BAD/GAA/FUCA2/RORA/OGT/PPP1CB/ESRRB/PC/ADPGK/MTOR/B4GALT1/GLYCTK/GDPGP1/SLC35A2/GCG/MAN2B2/PFKL/INPPL1/SESN2/RBP4/C1QTNF3/WDR5/G6PC/FAM3A/GHRL/NKX1-1	131
BP	GO:2000107	negative regulation of leukocyte apoptotic process	34/7096	47/18670	1.821e-06	9.875e-05	7.362e-05	NOD2/TSC22D3/PIP/BCL10/IRF7/ARG2/BCL6/SLC46A2/KITLG/MIF/CD74/LILRB1/CXCL12/IL7R/HCLS1/AXL/DOCK8/HIF1A/SLC39A10/IDO1/CCL5/IRS2/CCR5/BMP4/NOC2L/ADA/CXCR2/FADD/PTCRA/MERTK/PRKCQ/FOXP1/CCL19/CCR7	34
BP	GO:0032943	mononuclear cell proliferation	142/7096	274/18670	1.977e-06	0.0001063	7.927e-05	IGF1/PNP/CCR2/FYN/RAC2/PTPN6/LILRB2/ANXA1/CDKN1A/BST1/ELF4/LYN/CD55/SLC11A1/IRF1/ARG2/GPNMB/MNDA/LST1/CCND3/TNFRSF14/BCL6/SH3RF1/CD40/MIF/CEBPB/PTPRC/IL15/P2RX7/CD74/TNFRSF21/CD320/LILRB1/TICAM1/CD22/IL7R/DOCK8/TGFB1/PPP3CB/CCDC88B/PSMB10/LEP/TNFSF13B/PRKCD/CORO1A/TRAF6/CLC/FLT3LG/IL20RB/TLR4/PTPN22/FLT3/ZBTB7B/IMPDH1/HLA-DPB1/HLA-DPA1/HLA-E/NCK1/CD209/CASP3/ABL1/SLC39A10/PURA/IDO1/IL1B/CD151/AIF1/AGER/CCL5/RASAL3/AHR/HLA-DMB/ICOSLG/HMGB1/EFNB1/IGFBP2/IL7/TYROBP/IL6ST/HLA-G/IL6/IRS2/CTLA4/GLMN/ATM/VSIG4/AZI2/SCGB1A1/PDCD1LG2/BCL2/BMP4/BAX/NFATC2/MS4A1/CLCF1/IFNK/CR2/CD1D/IL12RB1/CD300A/CD274/LGALS9/EBI3/BTN2A2/HES1/ADA/IL18/FADD/CD276/TFRC/TNFRSF13B/TNFSF4/BTN3A1/CHRNB2/MSN/TNFRSF4/HAVCR2/CTPS1/PLCL2/SPTA1/TNFSF18/CD4/PIK3CG/GAPT/TNFRSF13C/IL12B/CD80/PRKCQ/GPR183/CCL19/IKZF3/MALT1/TIRAP/TNFSF8/CD3E/ATAD5/GJA1/TWSG1/CD24/IL23A/MEF2C/ZNF335	142
BP	GO:0043902	positive regulation of multi-organism process	103/7096	188/18670	2.014e-06	0.0001074	8.007e-05	CLEC7A/GRN/GAPDH/MIF/CIB1/LY96/LY86/AGO2/DDX60/CD74/CHD1/VPS37B/APOE/CHMP4B/UNC13B/PTAFR/STAU1/TRAF6/DDB1/TFAP4/ADARB1/IGF2R/TAF11/CCL5/DHX9/GTF2F2/SRPK2/PLB1/MDFIC/POLR2L/VAPB/TRIM11/SIGLEC16/CTDP1/ACVR1B/CDK9/POLR2H/PUM2/DDX3X/CCDC87/HDAC2/BCL2L11/TRIM21/FCER2/TARBP2/TBC1D20/CHMP2A/ANKRD17/HDAC4/TSG101/CFL1/TOP2B/LGALS1/FAM170B/SUPT4H1/INHBA/RSF1/GTF2F1/LGALS9/CYBA/IFIT1/SRPK1/HYAL3/VPS4B/PGLYRP4/POLR2F/POLR2D/PLCB1/C1QBP/CNOT7/PKN2/PRF1/ANXA2P2/POLR2K/FMR1/BAD/SMC3/HAVCR2/NELFCD/IFNG/VIP/LHFPL2/TRIM15/CD4/OPTN/PC/CSF1R/ANXA2/HPN/CCNT1/AURKA/ADAR/PPIB/POLR2I/ZCCHC3/SYDE1/CACNA1H/NUCKS1/PRKCA/P2RY1/TOP2A/POMZP3/SASH1	103
BP	GO:1902105	regulation of leukocyte differentiation	141/7096	272/18670	2.105e-06	0.0001114	8.303e-05	FOS/SIGLEC15/PNP/CCR2/NFKBIZ/PTPN6/LILRB2/ANXA1/LYN/IRF7/NOTCH2/IRF1/SOD1/EGR3/ATP6AP1/PTPN2/KLF10/SOX13/RNF41/BCL6/NLRP3/SH3RF1/LILRB3/SMAD7/SLC46A2/DUSP10/KITLG/CD2/FGL2/FBXW7/MYC/IL4R/CEBPB/CBFB/PTPRC/IL15/ADAM8/TNF/CD74/TESC/PRELID1/LILRB1/IL7R/HCLS1/AXL/TGFB1/SOCS5/ROR2/METTL3/LILRB4/TRAF6/ZBTB1/FLT3LG/TLR4/ZBTB7B/DTX1/ABL1/NFKBID/CASP8/AGER/RASGRP1/CLPTM1/MITF/PIK3R6/HMGB1/CREB1/IL7/TNFRSF18/TYROBP/TESPA1/HLA-G/TOX/TFE3/CYLD/CR1/TAL1/CTLA4/VNN1/TMEM64/NRARP/BMP4/CYP26B1/NFATC2/ID2/NME1/LAG3/PPP2R3C/INHBA/IL12RB1/LGALS9/PGLYRP4/EVI2B/BTN2A2/MMP14/ADA/HLX/PIAS3/IL18/FADD/AP3B1/TNFSF4/NFAM1/SART1/KAT2A/DCSTAMP/LRRC17/SOCS1/BAD/ZFP36L2/TREM2/C1QC/IFNG/CLDN18/FANCD2/PCID2/CD4/RB1/TLR3/INHA/IL12B/DROSHA/PRKCZ/CD80/TBX21/MTOR/FOXP1/RHOA/FOXN1/FANCA/SLC9B2/CD83/CCL19/IKZF3/MALT1/ZBTB16/HOXA7/PRKCA/SLAMF8/IL23A/HLA-DOA/APCS	141
BP	GO:0000302	response to reactive oxygen species	123/7096	232/18670	2.135e-06	0.000112	8.353e-05	KLF4/NQO1/SLC8A1/FOS/KLF2/FYN/DUSP1/ANXA1/GCH1/LDHA/PINK1/TXNIP/AIFM1/SOD1/STAT6/CAPN2/PLEKHA1/TNFAIP3/STAT1/MTR/GSTP1/PSAP/TNF/EZH2/HMOX1/ERCC6/MPV17/AKR1C3/PKD2/APOE/RELA/PDK2/AXL/UBE3A/CYP1B1/HGF/MAP1LC3A/CD36/PTK2B/PRDX1/MAPK7/PCGF2/PRKCD/HBB/MAPK13/HYAL2/KPNA4/NCF1/NET1/EGLN1/CAT/CASP3/ABL1/APTX/ADPRHL2/CRK/SIRT1/PPP1R15B/BMP7/TRPM2/OSER1/IL6/LRRK2/PPARGC1A/ETS1/MIR34A/SETX/SPHK1/SCGB1A1/HDAC2/PLK3/MAPK8/MMP9/ZNF580/BCL2/DNM2/PCNA/TPM1/MMP3/HNRNPD/FER/MAP3K5/KDM6B/ADA/UCP1/PXN/NFE2L2/IMPACT/DHFR/EGFR/TXN/TRAF2/SESN1/ADAM9/PRKAA1/MDM2/MAPK1/BAD/FOSL1/NR4A3/ATP7A/HP/CCNA2/AGAP3/MMP2/GPX1/IL18RAP/PDE8A/PDCD10/CCL19/SIGMAR1/MET/BAK1/CHUK/CCR7/ENDOG/MPO/SESN2/ERCC6L2/PDGFD/FOXO3/MAPK9/ZNF277	123
BP	GO:0045580	regulation of T cell differentiation	80/7096	139/18670	2.17e-06	0.0001129	8.42e-05	PNP/CCR2/NFKBIZ/LILRB2/ANXA1/IRF1/SOD1/EGR3/PTPN2/SOX13/BCL6/NLRP3/SH3RF1/SMAD7/SLC46A2/DUSP10/CD2/FGL2/IL4R/CBFB/PTPRC/IL15/ADAM8/CD74/PRELID1/IL7R/TGFB1/SOCS5/METTL3/LILRB4/ZBTB1/ZBTB7B/DTX1/ABL1/NFKBID/RASGRP1/CLPTM1/PIK3R6/HMGB1/IL7/TNFRSF18/TESPA1/HLA-G/CYLD/CR1/CTLA4/VNN1/NRARP/BMP4/CYP26B1/NFATC2/LAG3/IL12RB1/LGALS9/BTN2A2/ADA/HLX/IL18/AP3B1/TNFSF4/SART1/KAT2A/SOCS1/BAD/IFNG/FANCD2/IL12B/DROSHA/PRKCZ/CD80/TBX21/RHOA/FOXN1/FANCA/CD83/CCL19/MALT1/ZBTB16/IL23A/HLA-DOA	80
BP	GO:0002221	pattern recognition receptor signaling pathway	107/7096	197/18670	2.219e-06	0.0001146	8.543e-05	MYD88/S100A9/S100A8/ITGAM/NOD2/TLR1/TLR2/CLEC7A/APPL2/BCL10/LYN/IRF7/TNIP2/IRF1/GRAMD4/FCN1/CLEC4E/MARCO/TNFAIP3/RPS6KA3/CTSS/BIRC2/LY96/FLOT1/LGR4/LGMN/LILRA2/CTSK/UBE2N/DDX60/IRAK3/NFKBIA/TICAM1/MAPKAPK3/RELA/IRAK4/FFAR2/CD36/TLR5/UBE2D3/TAB3/TRAF6/IKBKG/TLR4/DDX58/PTPN22/TRAF3/UBE2D2/CACTIN/RSAD2/CASP8/CD300LF/CTSB/HMGB1/MFHAS1/CYLD/LSM14A/PUM2/TREML4/OTUD4/NPLOC4/IFIH1/SEC14L1/TAB1/MAPKAPK2/TNIP1/ANKRD17/BIRC3/NR1H3/TNIP3/TLR10/ALPK1/UBC/CD300A/WDFY1/CYBA/PGLYRP4/RAB7B/DMBT1/C1QBP/FADD/GPATCH3/HSP90B1/TLR8/RIOK3/TIFA/REG3G/HAVCR2/TRIM15/MAP3K1/NLRX1/TLR3/LBP/TYRO3/RTN4/UNC93B1/TSPAN6/TIRAP/CHUK/XIAP/APPL1/ZCCHC3/NR1H4/TLR6/S100A14/RFTN1/MIR146A	107
BP	GO:0032535	regulation of cellular component size	184/7096	370/18670	2.377e-06	0.0001218	9.077e-05	MYADM/RTN4R/CDC42EP4/FN1/VASP/EZR/KCNN4/DPYSL2/PEX11A/PLS1/ARF6/WNT5A/TSC1/SEMA4B/HCK/RHOBTB1/PLEKHG2/PPP1R15A/SPP1/RAB11A/ULK2/ALS2/TMSB10/PEX11G/P2RX7/SPIRE1/IFRD1/IQGAP2/APOE/GSK3B/ACTR2/CXCL12/TMOD3/TMEM123/LIMA1/IL7R/HCLS1/EVL/CDK4/TWF2/RDX/SIN3A/CLN8/PFN1/CDC42EP2/PAK1/MEGF8/PTK2B/CFL2/CAPZA2/SWAP70/PRKCD/SRF/LATS1/GMFG/CORO1A/BAIAP2/ARFGEF1/SCTR/SEMA4A/CAPG/NCK1/VEGFA/CDK5/TNFRSF12A/CLCN3/ABL1/PAFAH1B1/FCHSD1/GDI1/ARPC1A/SEMA4C/SLC12A9/CAPZA1/SEMA4D/LRP1/CREB1/MKKS/SH3BP1/RAC1/ARPIN/SPTBN1/ARPC1B/CDC42EP3/DCC/CYFIP1/MYO1C/GNB3/CORO1B/BBS4/ARF1/SLC12A2/SEMA6B/ARPC5L/SLC12A8/LAMTOR4/NRP1/DISC1/SEMA3B/COTL1/DNM2/AVIL/L1CAM/CFL1/PRR16/RAB5A/LPAR3/KANK1/TRIOBP/IST1/ARHGAP18/ADD3/NDEL1/OLFM1/GRB2/AKT1S1/PLEK/JMY/ACTR3B/WDR36/FER/SEMA5A/DMTN/FSTL4/ACTR3/LAMTOR5/E2F4/LRRC8A/PPP1CA/LMOD3/VAV1/PEX11B/CAV3/SCIN/PREX1/SLIT2/CCL26/DEPTOR/RAB22A/SEMA5B/MSN/ARPC4/MAP3K13/RUFY3/PLXNA3/SPTA1/ATP7A/CLNS1A/RET/RAB3B/HSP90AB1/SPTBN2/SLC12A1/SLC12A7/ARPC2/KANK3/AP2M1/MTOR/KCNMA1/RHOA/TRPV4/PICK1/RTN4/SNX9/SLC12A4/CRABP2/FGF13/WNT7A/CCR7/WAS/PICALM/RHOBTB2/CCL24/SHANK3/KEL/BIN1/NCKAP1/FCHSD2/MACF1/TRPV2/TRIM46/SLC12A6/BMPR2/FMN1	184
BP	GO:0071887	leukocyte apoptotic process	63/7096	104/18670	2.464e-06	0.0001252	9.335e-05	NOD2/TSC22D3/PIP/ANXA1/BCL10/LYN/IRF7/WNT5A/ARG2/BCL6/SLC46A2/KITLG/MIF/P2RX7/ADAM8/SLC7A11/CD74/TNFRSF21/PRELID1/LILRB1/CXCL12/IL7R/HCLS1/AXL/DOCK8/HIF1A/RAPGEF2/CLC/CASP3/SLC39A10/IDO1/NFKBID/DFFA/CCL5/SIRT1/IL6/IRS2/CCR5/FNIP1/BCL2L11/BMP4/BAX/NOC2L/PIK3CD/CD3G/CD274/LGALS9/BIRC7/ADA/CXCR2/FADD/ADAM17/PTCRA/MERTK/NR4A3/PRKCQ/FOXP1/CCL19/BAK1/CCR7/PDCD1/MEF2C/PIK3CB	63
BP	GO:0001910	regulation of leukocyte mediated cytotoxicity	50/7096	78/18670	2.619e-06	0.0001313	9.791e-05	ITGAM/SERPINB9/STX7/CD1C/PTPRC/P2RX7/CD1E/LAMP1/LILRB1/IL7R/CD226/PPP3CB/LEP/FAM49B/HLA-F/HLA-E/HLA-B/CLEC12B/AGER/RASGRP1/CD1B/PIK3R6/CRK/TYROBP/HLA-G/DNASE1/HLA-C/PVR/LAG3/CD1D/IL12RB1/CD1A/LGALS9/ULBP2/CRTAM/VAV1/KIR2DL4/FADD/AP1G1/HLA-A/HAVCR2/NCR3/SERPINB4/IL12B/SH2D1A/MICA/NCR1/IL18RAP/IL23A/CXCL6	50
BP	GO:0002237	response to molecule of bacterial origin	172/7096	343/18670	2.625e-06	0.0001313	9.791e-05	S100A8/JUNB/FOS/NOD2/TLR1/CX3CR1/TLR2/PTGER4/LILRB2/ACP5/GCH1/BCL10/SBNO2/LYN/CD55/ZFP36/SLC11A1/TNIP2/WNT5A/PTGER2/VIM/HCK/JUND/CAPN2/PTGS2/NLRP3/PPARD/TFPI/DUSP10/TNFAIP3/RPS6KA3/MIF/LY96/LY86/PPBP/LILRA2/ADH5/CXCL9/CEBPB/SCARB1/MGST2/JAK2/GSTP1/CXCL11/IFNAR1/P2RX7/TNF/IRAK3/PAF1/NFKBIA/CXCL10/NFKB1/LILRB1/PLAA/TICAM1/MIR142/MAPKAPK3/RELA/AXL/CDK4/TGFB1/CSF2RB/ALAD/PTAFR/HPGD/CD36/NR1H2/TRAF6/NFKB2/CXCL13/TLR4/PTPN22/ABR/PDE4B/CASP3/CACTIN/ABL1/NFKBIB/IDO1/CASP8/ABCA1/IL1B/CCL5/PLCG2/HMGB1/CMPK2/THBD/TNFRSF11A/IL1RN/IL6/PPARGC1A/CCR5/TIMP4/SPARC/BCR/SCGB1A1/PDCD1LG2/HDAC2/CD96/AKAP8/MGST1/CYP1A2/MAPK8/MAPKAPK2/SERPINE1/HMGB2/OTUD5/HNRNPA0/NR1H3/SGMS1/TNIP3/CASP1/PRPF8/CD274/LGALS9/FER/FZD5/CNR2/F2R/IRF8/IL18/ADAM17/ATP2A2/MAOB/ADAM9/TNFSF4/HAMP/MAPK1/SIGIRR/CYP27B1/TREM2/SRR/HAVCR2/PALM3/BDKRB1/GNG12/LACRT/CTSG/CNP/REN/LBP/WDR35/IL12B/MTDH/TRIM6/CD80/HDAC5/FOXP1/PLSCR4/RHOA/CDC73/SNCA/CX3CL1/PDCD4/MALT1/TIRAP/CHUK/CCR7/AKIRIN2/MPO/GJA1/NR1H4/PRKCA/CD24/TLR6/CXCL6/MEF2C/UPF1/SASH1/S100A14/IL37/MIR146A	172
BP	GO:1903557	positive regulation of tumor necrosis factor superfamily cytokine production	55/7096	88/18670	2.702e-06	0.000133	9.917e-05	NOD2/CCR2/TLR1/TLR2/CLEC7A/WNT5A/AZU1/LILRA5/MIF/CD2/LY96/LILRA2/JAK2/PTPRC/ADAM8/TICAM1/PTAFR/HSPB1/CD36/FRMD8/LEP/TLR4/DDX58/HLA-E/AGER/RASGRP1/DHX9/ARHGEF2/HMGB1/CLU/TYROBP/MAVS/LRRK2/HDAC2/IFIH1/MAPKAPK2/LGALS9/CYBA/CYBB/FZD5/IFNGR1/FADD/PSEN1/HAVCR2/IFNG/TLR3/LBP/IL12B/ZBTB20/APP/CCL19/TIRAP/HMGB4/IL23A/PTPRJ	55
BP	GO:0032760	positive regulation of tumor necrosis factor production	54/7096	86/18670	2.703e-06	0.000133	9.917e-05	NOD2/CCR2/TLR1/TLR2/CLEC7A/WNT5A/AZU1/LILRA5/MIF/CD2/LY96/LILRA2/JAK2/PTPRC/TICAM1/PTAFR/HSPB1/CD36/FRMD8/LEP/TLR4/DDX58/HLA-E/AGER/RASGRP1/DHX9/ARHGEF2/HMGB1/CLU/TYROBP/MAVS/LRRK2/HDAC2/IFIH1/MAPKAPK2/LGALS9/CYBA/CYBB/FZD5/IFNGR1/FADD/PSEN1/HAVCR2/IFNG/TLR3/LBP/IL12B/ZBTB20/APP/CCL19/TIRAP/HMGB4/IL23A/PTPRJ	54
BP	GO:0009100	glycoprotein metabolic process	205/7096	419/18670	2.721e-06	0.000133	9.917e-05	IGF1/HS3ST2/HEXB/VCAN/TMTC3/PGM3/EXTL2/CHSY1/MANBA/NDST2/HS2ST1/MCFD2/MGAT2/DAD1/B3GNT8/RNF103/VEGFB/PPARD/CHP1/MGAT5/MAN1C1/FBXO6/POMGNT2/LFNG/GALNT14/IDS/RNF139/AGO2/IL15/FUT4/SOAT1/IMPAD1/EXT2/EXT1/TRIM13/HEXA/CHST13/FUT7/CST3/FAM20B/TET2/MGAT4B/EDEM1/ITM2B/B3GNT2/MAN2A2/ARSB/SGSH/HIF1A/STT3A/MAN2B1/LEP/NAGPA/PTX3/GNPTAB/B4GALT6/ARFGEF1/CSGALNACT1/POGLUT1/ALG2/BMP2/KRTCAP2/B3GNT5/TRAK2/CSPG4/OST4/PMM2/ST6GALNAC4/CYTL1/ITM2A/UBE2J1/ST3GAL2/GALNT7/MMP12/XYLT1/LMF1/CHST11/ERP44/SLC35D1/MUC2/B3GALT6/FKRP/AGA/GLCE/ALG6/UBE2G2/IDUA/SDF2L1/DPY19L4/DPM1/ADAMTS12/EDEM2/GALNT6/CHST14/TMTC2/SULF2/BACE2/SERP1/GCNT1/XYLT2/RPN2/GALNT12/DOLK/AATF/MUC1/GALNT10/HPSE/STT3B/BCL2/TNIP1/NUDT14/ALG12/ALG10/MGAT3/GAL3ST4/MAN1B1/NDST1/GANAB/CSGALNACT2/ASGR2/HS3ST1/SPOCK2/LMAN1/DOLPP1/FUT6/B4GALT5/ST8SIA4/BCAN/NGLY1/MGAT5B/ALG13/DERL2/ABCA7/MAN1A2/MOGS/HS3ST3B1/POMT1/PLCB1/TUSC3/TMEM258/SLC35C1/PCSK6/COL2A1/NUS1/DHDDS/GALNT9/SRD5A3/ST6GALNAC5/XXYLT1/GFPT1/POMT2/PSEN1/DPM3/B3GNT4/GGTA1P/ST3GAL1/DPY19L2/TCF7L2/MUC6/NECAB3/OGT/ATP7A/FBXO27/CHST12/TRAK1/FBXO44/GCNT2/ST6GALNAC3/B3GAT3/HBEGF/MUCL1/RNF185/RNF5/ST6GALNAC6/COG7/HS3ST6/ASGR1/VCP/C1GALT1/B3GALT5/GFPT2/B4GALT1/ENGASE/GALNT1/CCL19/ALG14/EDEM3/MAN2B2/CCR7/BMPR1B/ST8SIA1/DDOST/ST3GAL5/DPAGT1/DPY19L2P2/ALG8/OS9/APCS/TET1/ALG3/GALNT15/ADAMTS9/CHST7/ACOT8/BMPR2	205
BP	GO:0032635	interleukin-6 production	90/7096	161/18670	2.856e-06	0.0001386	0.0001033	MYD88/NOD2/KLF2/TLR1/TLR2/PTPN6/IL27RA/LILRB2/CLEC7A/BCL10/WNT5A/CSK/SYT11/STAT3/CAPN2/LILRA5/TNFAIP3/BANK1/MBP/LILRA2/NLRP12/CEBPB/P2RX7/TNF/IRAK3/CD74/IL1RAP/SLAMF1/TICAM1/HGF/ARRB1/PTAFR/SOCS5/CD36/LEP/MAPK13/TRAF6/HYAL2/TLR4/DDX58/PTPN22/IL1B/AIF1/AGER/DHX9/ARHGEF2/HMGB1/IL1RN/TYROBP/MAVS/SIGLEC16/IL6/CD200R1/AZI2/IFIH1/ASH1L/ADORA2B/MAPKAPK2/CD47/LGALS9/CYBA/RABGEF1/RAB7B/F2R/IL18/TNFSF4/TLR8/TREM2/HAVCR2/TSLP/NLRX1/TLR3/LBP/ZBTB20/IL18RAP/TRPV4/C5AR2/APP/CX3CL1/TIRAP/AKIRIN2/HMGB4/NR1H4/NLRC3/TLR6/C1QTNF3/IL17RC/GHRL/IL37/MIR146A	90
BP	GO:0070661	leukocyte proliferation	152/7096	298/18670	2.897e-06	0.0001395	0.000104	IGF1/PNP/CCR2/FYN/RAC2/PTPN6/LILRB2/ANXA1/CDKN1A/BST1/ELF4/LYN/CD55/SLC11A1/IRF1/ARG2/GPNMB/MNDA/LST1/CCND3/TNFRSF14/BCL6/SH3RF1/TNFAIP3/CD40/KITLG/MIF/CEBPB/GSTP1/PTPRC/IL15/P2RX7/CD74/TNFRSF21/CD320/LILRB1/TICAM1/CD22/IL7R/DOCK8/TGFB1/PPP3CB/CCDC88B/PSMB10/LEP/TNFSF13B/PRKCD/CORO1A/TRAF6/CLC/FLT3LG/TCIRG1/IL20RB/TLR4/PTPN22/FLT3/ZBTB7B/IMPDH1/HLA-DPB1/HLA-DPA1/HLA-E/NCK1/CD209/CASP3/ABL1/SLC39A10/PURA/IDO1/IL1B/CD151/AIF1/AGER/CCL5/RASAL3/AHR/HLA-DMB/ICOSLG/HMGB1/EFNB1/IGFBP2/IL7/CLU/TYROBP/IL6ST/HLA-G/IL6/IRS2/CTLA4/GLMN/ATM/VSIG4/AZI2/SCGB1A1/PDCD1LG2/BCL2/CCL8/BMP4/BAX/NFATC2/MS4A1/CLCF1/IFNK/CR2/CD1D/IL12RB1/CD300A/CD274/LGALS9/EBI3/BTN2A2/HES1/ADA/IL18/FADD/CD276/TFRC/TNFRSF13B/TNFSF4/BTN3A1/CHRNB2/MSN/TREM2/TNFRSF4/HAVCR2/CTPS1/PLCL2/SPTA1/TNFSF18/CD4/PIK3CG/GAPT/TNFRSF13C/IL12B/CD80/CSF1R/PRKCQ/GPR183/CX3CL1/CCL19/IKZF3/MALT1/TIRAP/TNFSF8/CD3E/ATAD5/GJA1/GREM1/TWSG1/CD24/IL23A/MEF2C/ZNF335	152
BP	GO:0051249	regulation of lymphocyte activation	233/7096	485/18670	3.236e-06	0.0001547	0.0001153	IGF1/NOD2/PNP/CCR2/FYN/RAC2/NFKBIZ/PTPN6/IL27RA/LILRB2/ANXA1/CDKN1A/BST1/CLEC7A/BCL10/LYN/MAD2L2/CD55/TNIP2/IRF1/CSK/SOD1/ARG2/GPNMB/EGR3/MNDA/LST1/STAT6/PTPN2/SOX13/TNFRSF14/RNF41/BCL6/NLRP3/SH3RF1/SMAD7/SLC46A2/DUSP10/TNFAIP3/BANK1/CD40/MIF/CD2/FGL2/IL4R/CEBPB/CBFB/MAP3K8/PTPRC/IL15/HFE/ADAM8/LAMP1/CD74/TNFRSF21/CD320/PRELID1/LILRB1/TICAM1/DPP4/DUSP3/CD22/IL7R/AXL/DOCK8/TGFB1/CCDC88B/PAK1/SOCS5/LEP/TNFSF13B/METTL3/FAM49B/HLA-F/CORO1A/LILRB4/TRAF6/ZBTB1/CLC/FLT3LG/IL20RB/TLR4/PTPN22/ZBTB7B/SOCS6/HLA-DPB1/HLA-DPA1/HLA-E/NCK1/DTX1/CD209/CASP3/ABL1/SLC39A10/IDO1/NFKBID/PAK2/IL1B/AIF1/SIRPB1/AGER/CCL5/RASGRP1/RASAL3/CLPTM1/AHR/PIK3R6/HLA-DMB/ICOSLG/HMGB1/EFNB1/IGFBP2/IL7/TNFRSF18/TYROBP/IL6ST/TESPA1/HLA-G/RAC1/TOX/TRBC1/IL6/IRS2/LCK/CYLD/CR1/FLOT2/CTLA4/GLMN/ATM/TIGIT/VSIG4/SCGB1A1/VNN1/PDCD1LG2/NRARP/MLH1/BCL2/BMP4/PARP3/BLOC1S3/CYP26B1/NFATC2/ID2/CD47/CLCF1/LGALS1/LAG3/PPP2R3C/INHBA/CD1D/IL12RB1/GRB2/CD300A/CD274/RHBDD3/LGALS9/LAX1/EBI3/ICOS/PGLYRP4/BTN2A2/MMP14/HES1/ADA/HLX/VAV1/IL18/FADD/AP3B1/CD276/TFRC/TNFRSF13B/TNFSF4/NFAM1/SART1/AP1G1/KAT2A/MERTK/CHRNB2/PAG1/SOCS1/SIRPG/BAD/ZFP36L2/TNFRSF4/HAVCR2/IFNG/SPTA1/CD5/EXOSC3/TNFSF18/FANCD2/PCID2/CD4/INHA/TNFRSF13C/IL12B/DROSHA/SLA2/MICA/PRKCZ/CD80/TBX21/PRKCQ/RHOA/TYRO3/APLF/GPR183/FOXN1/FANCA/CD83/EXOSC6/CCL19/IKZF3/MALT1/TIRAP/ZBTB16/CCR7/TNFSF8/PAXIP1/CD3E/ATAD5/PDCD1/TWSG1/SLAMF8/CD24/IL23A/HLA-DOA/LAT/IGHD/MEF2C/ZNF335	233
BP	GO:0034976	response to endoplasmic reticulum stress	146/7096	285/18670	3.314e-06	0.0001572	0.0001172	SRPX/TMTC3/EXTL2/AIFM1/LMNA/ERP29/TPP1/PTPN2/RNF103/TMBIM6/PPP1R15A/UBA5/PMAIP1/FBXO6/DDRGK1/CREBRF/FLOT1/CEBPB/RNF139/BCAP31/FKBP14/ERP27/NUPR1/PDIA3/TRIM13/GSK3B/ATF4/TMEM129/EDEM1/UBE4B/UBE2K/TLN1/ITPR1/TMEM117/SGTA/WFS1/SEC61B/UFC1/ERLIN1/SSR1/RNF175/EIF2B5/GORASP2/HSPA5/NCK1/HERPUD2/TMEM33/FOXRED2/PARP16/CREB3L2/UBE2J1/SHC1/ERLIN2/PML/ERP44/WIPI1/VAPB/CLU/SIRT1/PPP1R15B/CCND1/EIF2S1/UBE2G2/SDF2L1/GOSR2/EDEM2/LRRK2/CREB3L4/SERP1/RNFT1/TOR1A/PDIA6/UBXN8/KDELR3/BCL2L11/NPLOC4/TXNDC12/SERINC3/STT3B/UBQLN2/BCL2/BAX/PSMC6/CTH/ASNS/UFM1/MAN1B1/DNAJC10/DERL1/GET4/CREB3/PDX1/ACADVL/MAP3K5/DNAJB9/CANX/DERL2/STUB1/CALR/RASGRF1/NFE2L2/TNFRSF10B/ATXN3/NFE2L1/EIF2AK2/YOD1/CTDSP2/TRAF2/ATP2A2/HSP90B1/CASP4/GFPT1/BFAR/POMT2/PLA2G6/TMUB2/TBL2/UBXN1/FBXO27/HYOU1/FBXO44/RNF185/RNF5/PPP2R5B/YIF1A/EIF2AK4/VCP/MANF/SCAMP5/MBTPS2/ERN1/NRBF2/BAK1/ANKS4B/USP19/MBTPS1/EDEM3/PREB/TARDBP/SESN2/ARFGAP1/DNAJC18/HDGF/ERLEC1/OS9/ATF6B	146
BP	GO:0009896	positive regulation of catabolic process	206/7096	423/18670	3.823e-06	0.0001801	0.0001343	IGF1/CBFA2T3/TRIM32/EZR/TMTC3/ATG7/SNX1/PINK1/ZFP36/WWP1/WNT5A/TSC1/C9orf72/BARD1/PFKFB3/TPCN1/OAZ2/GNAI3/RNF41/SMAD7/TNFAIP3/TOB1/KEAP1/DDRGK1/FBXW7/DHRSX/CTSC/SEC22B/RNF139/AGO2/P2RX7/BCAP31/ADAM8/TNF/YTHDF3/HMOX1/MOV10/NUPR1/HNRNPR/METTL14/TRIM13/GIGYF2/APOE/GSK3B/MAGEF1/BTG2/RNF19B/FBXL5/TICAM1/EDEM1/SH3BP4/CDC37/RDX/SGTA/HIF1A/TRIM22/ZFAND2A/SOCS5/PTK2B/CSNK1D/PRKCD/PTTG1IP/INSR/METTL3/TFEB/RNF217/IKBKG/DDB1/TP53INP2/OAZ3/CEBPA/SPTLC2/PLK2/ANKIB1/GCLC/RAB3GAP1/IL1B/PSMC4/FURIN/UQCC2/LDLR/DAPK1/ZC3H12D/LRP1/HMGB1/CLU/SIRT1/GPSM1/IL6/IRS2/SNX33/EDEM2/LRRK2/PFKFB4/FLCN/SUMO1/STX5/APOA5/PTK2/HSPBP1/ATM/CSNK1A1/CSNK1E/RNFT1/DTX3L/ZC3HAV1/ARIH2/BCL2L11/PLK3/KAT5/FTO/VPS13D/EPM2A/DISC1/TRIM21/UBQLN2/GTPBP1/PFKFB1/MEFV/ATG4B/NEDD4/BAX/TIPARP/CDKN1B/TRIB2/ADRB2/BBS7/DET1/TNRC6B/CPT1A/RHBDD3/NKD2/ST20/TNRC6A/HNRNPD/CPEB3/KLHL40/PFKFB2/ARNT/STUB1/DTL/NFE2L2/ATXN3/ULK1/CNOT7/MUL1/WWP2/PPARA/ASB11/CAV3/MID2/BAG2/SESN1/ADAM9/DVL1/PRKAA1/PSEN1/FMR1/MDM2/SH3GLB1/SUPV3L1/SMCR8/NPRL2/MSN/PSMC1/BAD/ZFP36L2/TREM2/DXO/IFNG/VIP/TRIM65/CUL4B/RNF185/CLEC16A/LACRT/OPTN/MTDH/ESRRB/EIF2AK4/PSMC2/ZBTB20/VCP/AURKA/APP/PIM2/SNCA/SNX9/RBX1/ABCD1/PNPT1/LPCAT1/KCNE2/CHFR/ROCK2/ENDOG/GJA1/NNT/HMGB4/SESN2/PACSIN3/FOXO3/PLEKHN1/UPF1/PIK3CB/MAPK9	206
BP	GO:0006644	phospholipid metabolic process	209/7096	430/18670	3.852e-06	0.0001802	0.0001343	KLF4/FPR2/HTR2B/NOD2/LPCAT2/SLC27A1/CDS1/HEXB/PLA2G12A/SGMS2/SOCS3/LYN/HADHB/ENPP2/FLT1/CHPT1/DGKA/CAPN2/GPAM/ABHD4/PLSCR1/WDR91/PPARD/PLEKHA1/MBOAT7/GDE1/MTMR12/ABHD6/ABHD12/GPCPD1/PIGV/ATG14/WDR81/CDS2/PIGP/APOC1/SCARB1/PTDSS2/PLA2G7/MBOAT1/IMPAD1/PTPMT1/PLBD1/CISH/PIGK/CETP/INPP1/LPGAT1/PLAA/PIK3R3/PTPN13/PNPLA6/PLD1/PNPLA3/SACM1L/CSNK2A2/TGFB1/CLN8/HMGCS1/PIGN/STARD10/IP6K1/SOCS5/PTK2B/SYNJ1/PITPNM1/PRKCD/PLA1A/PIK3IP1/NAPEPLD/DDHD1/TTC7A/FLT3/SOCS6/FGR/SERINC1/FIG4/SPTLC2/FAM126A/AGPAT3/PAFAH1B1/SAMD8/PLA2G15/CLN3/PLCG2/LDLR/PLB1/PIK3R6/FDPS/CSNK2B/P2RY12/PIGF/IDH1/SYNJ2/STARD7/GPX4/CDIPT/FABP3/PIGB/DPM1/OCRL/SOCS7/PDGFB/EPHA8/ABHD3/AGPAT4/GPAA1/SH3YL1/RAB38/ALDH5A1/GNB3/APOA5/PNPLA8/PTK2/ATM/ARF1/ENPP7/DOLK/CRLS1/PIGM/MFSD2A/PLA2G3/PLEKHA8/IDI1/MBOAT2/SBF1/LCAT/SERINC3/MTMR4/TMEM86B/MPPE1/INPP5K/IMPA2/MTMR6/PIK3CD/PRDX6/SGMS1/PI4K2A/RAB5A/PIGQ/ACP6/MTMR2/INPP5F/PLEK/DOLPP1/PDGFA/FAR1/PIGO/HADHA/CHKA/PLCD1/PIGH/PLCB1/FABP5/AGK/NUS1/DHDDS/AGPAT5/SRD5A3/DBI/PLD2/PLCD4/CPNE1/DPM3/MTMR3/PLEKHA3/APOA1/SOCS1/PLA2G6/PIGT/GNPAT/CPNE3/MTMR9/SLC44A2/SMPD1/TMEM38B/PIK3CG/SLA2/SERAC1/CSF1R/AGPAT1/PIP5K1B/CHAT/TAZ/SNCA/VAC14/ABHD16A/CCL19/LPCAT1/CCKBR/CHKB/SMPD2/PGS1/CCR7/AGPAT2/SOCS2/SERINC2/PGAP3/INPPL1/NR1H4/ARF3/EFR3A/PGAP1/DPAGT1/INPP5A/PIK3CB/IMPA1/PI4KB/LPCAT3	209
BP	GO:0019359	nicotinamide nucleotide biosynthetic process	83/7096	147/18670	4.027e-06	0.0001857	0.0001384	IGF1/CBFA2T3/HK3/NAMPT/QPRT/LDHA/FBP1/PARP9/PGK1/STAT3/PFKFB3/NUP62/NUP160/PFKM/PTGS2/PFKP/GAPDH/NUP214/NMNAT3/SLC2A6/P2RX7/NUPR1/PGAM1/PKM/GALK1/EIF6/TPI1/ZBTB7A/NUP85/HIF1A/SEH1L/INSR/ALDOC/NUP43/NMNAT1/ENO1/IDO1/ALDOA/PARP16/NADK2/POM121/OGDH/GPI/PFKFB4/PPARGC1A/IDH2/KYNU/HAAO/DHTKD1/PRKAG2/MYOG/NCOR1/PFKFB1/NUP88/HDAC4/NUP107/NMRK2/FOXK2/NMNAT2/DDIT4/PGK2/PFKFB2/ARNT/PPARA/NUP93/IDO2/SLC5A8/PRKAA1/PSEN1/NUP205/ENO2/SLC4A1/NUP50/IFNG/PRKAG1/OGT/ESRRB/ZBTB20/ADPGK/APP/PFKL/POM121C/AAAS	83
BP	GO:0019363	pyridine nucleotide biosynthetic process	83/7096	147/18670	4.027e-06	0.0001857	0.0001384	IGF1/CBFA2T3/HK3/NAMPT/QPRT/LDHA/FBP1/PARP9/PGK1/STAT3/PFKFB3/NUP62/NUP160/PFKM/PTGS2/PFKP/GAPDH/NUP214/NMNAT3/SLC2A6/P2RX7/NUPR1/PGAM1/PKM/GALK1/EIF6/TPI1/ZBTB7A/NUP85/HIF1A/SEH1L/INSR/ALDOC/NUP43/NMNAT1/ENO1/IDO1/ALDOA/PARP16/NADK2/POM121/OGDH/GPI/PFKFB4/PPARGC1A/IDH2/KYNU/HAAO/DHTKD1/PRKAG2/MYOG/NCOR1/PFKFB1/NUP88/HDAC4/NUP107/NMRK2/FOXK2/NMNAT2/DDIT4/PGK2/PFKFB2/ARNT/PPARA/NUP93/IDO2/SLC5A8/PRKAA1/PSEN1/NUP205/ENO2/SLC4A1/NUP50/IFNG/PRKAG1/OGT/ESRRB/ZBTB20/ADPGK/APP/PFKL/POM121C/AAAS	83
BP	GO:0022604	regulation of cell morphogenesis	232/7096	484/18670	4.15e-06	0.0001887	0.0001407	MYADM/S100A10/RTN4R/CDC42EP4/FN1/FYN/EZR/HEXB/ANXA1/SIPA1L1/DPYSL2/SKIL/CDC42SE1/DNM3/ARHGEF18/ENPP2/WNT5A/GBP1/FMNL3/FMNL1/LST1/SEMA4B/ARAP1/DIAPH1/HCK/SPP1/RAB11A/NEDD9/FLNA/FBLIM1/RHOC/MAP2K1/CIB1/ULK2/ACTN4/YWHAH/CD44/FGD6/FGD5/DVL2/EPHB2/MOV10/ARHGDIA/IFRD1/APOE/GSK3B/ZEB2/ZSWIM6/ACTR2/PLAA/CXCL12/PTPRO/RND3/PLXNB2/LRP8/UBE3A/TWF2/RDX/SIN3A/CDC42EP2/PARVB/PAK1/RAPGEF2/MEGF8/SS18L2/PTK2B/PLEKHO1/PLXNC1/BCL11A/SRF/CORO1A/RHOG/BAIAP2/SEMA4A/ITGA7/CDC42SE2/FGR/ZRANB1/VEGFA/CDK5/TNFRSF12A/TRAK2/ABL1/PAFAH1B1/ATP10A/ALDOA/LARP4/GDI1/GRIP1/S100B/SEMA4C/SEMA4D/PHIP/ANKRD27/LRP1/ZNF135/CRK/CCL7/PDZD8/RAC1/ARPIN/CAPRIN1/KALRN/CDC42EP3/LRRK2/DCC/CYFIP1/S100A13/BCL9L/MYCBP2/DOCK5/RHOU/ARC/CORO1B/SPARC/PTK2/MYH9/SEMA6B/PDLIM5/PLXNA1/CCL13/NRP1/DISC1/SEMA3B/PLXND1/DNM2/PRPF40A/TPM1/NEDD4/WDPCP/L1CAM/ERMN/MARK2/ZMYM2/RHOQ/UNC13D/CFL1/LPAR3/KANK1/TRIOBP/IST1/ARHGAP18/NDEL1/SYNGAP1/RHOV/DAB1/OLFM1/WDR36/SEMA5A/RHOF/LPAR1/DMTN/FSTL4/ZMPSTE24/BHLHB9/CORO1C/DNM1L/CALR/RHOH/NSMF/C1QBP/MUL1/AMIGO1/RCC2/SS18L1/FZD4/PREX1/ITSN2/SLIT2/DVL1/PSEN1/FMR1/MKLN1/SEMA5B/GNA13/CHRNB2/SHOX2/APOA1/ZMYM5/EPB41/MSN/MYO10/RASAL1/MAP3K13/RUFY3/FGD3/EPB42/RHOBTB3/PLXNA3/SPTA1/SYT1/RET/TRAK1/CPNE9/ZMYM4/ZMYM3/IL1RAPL1/KNDC1/TACSTD2/PLXNA2/FGD4/SYT2/ARPC2/NR2E1/SYT4/RELN/CSF1R/HPN/CHODL/RHOA/BRSK1/LIMS1/RTN4/DAG1/ITGB1BP1/PARP6/CRABP2/RIMS2/FGF13/LRP4/WNT7A/CCL24/LZTS1/SHANK3/KEL/P2RY1/MACF1/TRPV2/NTRK2/TRIM46/CAMK2B/BMPR2	232
BP	GO:0034340	response to type I interferon	60/7096	99/18670	4.151e-06	0.0001887	0.0001407	MYD88/PTPN6/GBP2/IRF7/IRF1/WNT5A/PTPN2/NLRC5/PSMB8/XAF1/STAT1/OASL/IFNAR1/IFITM2/EGR1/IFITM1/YTHDF3/IFITM3/CDC37/MX2/UBE2K/IFI35/IRF9/IFIT3/ISG20/METTL3/HLA-F/OAS3/IFI27/HLA-E/HLA-B/CACTIN/SP100/RSAD2/IFIT2/SAMHD1/MMP12/OAS2/ISG15/HLA-G/MAVS/LSM14A/HLA-C/SHMT2/TYK2/MX1/RNASEL/ZBP1/IFIT1/IRF2/IRF8/CNOT7/MUL1/FADD/HLA-A/JAK1/HSP90AB1/IFNAR2/TRIM6/ADAR	60
BP	GO:0009123	nucleoside monophosphate metabolic process	185/7096	375/18670	4.264e-06	0.0001913	0.0001426	IGF1/CBFA2T3/HK3/UPP1/LDHA/PINK1/FBP1/PGK1/VPS9D1/STAT3/PFKFB3/NUP62/NUP160/PFKM/UQCRC2/PFKP/GAPDH/SLC25A25/NUP214/SLC2A6/P2RX7/UQCR11/NDUFA8/NUPR1/AK3/PGAM1/AK2/PKM/GALK1/EIF6/TPI1/MPP1/ZBTB7A/NDUFC1/TGFB1/GMPS/DGUOK/NUP85/CLPX/HIF1A/ISCU/SEH1L/NDUFB11/ADK/INSR/ALDOC/NDUFS3/CDADC1/GUK1/PAICS/NUP43/IMPDH1/NDUFA3/NMNAT1/ATP6V1A/ENO1/DNAJC30/ALDOA/AK8/UQCC2/NDUFA11/PARG/CMPK1/TK1/POM121/RFK/OGDH/CMPK2/CHCHD10/UQCR10/NUDT9/COX7C/GPI/ATP6V1B2/PFKFB4/PPARGC1A/FLCN/DNPH1/COX7A2L/DHTKD1/NDUFA4/SLC25A12/SHMT2/LDHC/PRKAG2/MYOG/NCOR1/COX4I2/NDUFA1/NUDT3/PFKFB1/GMPR2/ATIC/NUP88/HDAC4/ATP1B1/NUDT5/TEFM/COQ9/NUP107/PRPS1/PPAT/COA6/COX15/TYMS/NDUFA10/FOXK2/NDUFB1/DDIT4/NDUFB5/UQCRQ/AMPD2/PGK2/PFKFB2/ADA/DCK/ARNT/DNM1L/NDUFS1/SHMT1/UCK1/SLC25A33/PPARA/NUP93/SLC25A13/TK2/NDUFB8/PRKAA1/PSEN1/DNAJC15/NUP205/AK6/ENO2/PID1/SURF1/DCTD/NDUFB6/BAD/SLC4A1/PRPS1L1/TREM2/CAD/NUP50/IFNG/PRKAG1/OGT/ATP7A/PRPS2/NDUFB3/SDHA/ESRRB/ZBTB20/VCP/NDUFS7/ADPGK/NDUFV2/ND4/SDHD/RHOA/UCKL1/TAZ/APP/SNCA/NT5M/UQCRB/UPP2/ATP6V1B1/AMPD3/ABCD1/NDUFB2/SDHAF2/LHPP/MYH3/COX6C/DUT/ATP1A2/PFKL/CTNS/NDUFS2/PNKP/POM121C/AAAS/FIGNL1/NDUFA7/COX7B	185
BP	GO:0046031	ADP metabolic process	73/7096	126/18670	4.269e-06	0.0001913	0.0001426	IGF1/CBFA2T3/HK3/LDHA/FBP1/PGK1/STAT3/PFKFB3/NUP62/NUP160/PFKM/PFKP/GAPDH/NUP214/SLC2A6/P2RX7/NUPR1/AK3/PGAM1/AK2/PKM/GALK1/EIF6/TPI1/ZBTB7A/NUP85/HIF1A/SEH1L/INSR/ALDOC/NUP43/ENO1/ALDOA/POM121/OGDH/NUDT9/GPI/PFKFB4/PPARGC1A/DHTKD1/SLC25A12/PRKAG2/MYOG/NCOR1/PFKFB1/NUP88/HDAC4/NUP107/FOXK2/DDIT4/PGK2/PFKFB2/ARNT/PPARA/NUP93/PRKAA1/PSEN1/NUP205/ENO2/BAD/SLC4A1/NUP50/IFNG/PRKAG1/OGT/ESRRB/ZBTB20/ADPGK/APP/AMPD3/PFKL/POM121C/AAAS	73
BP	GO:0051196	regulation of coenzyme metabolic process	58/7096	95/18670	4.301e-06	0.0001914	0.0001427	IGF1/CBFA2T3/PDK4/FBP1/STAT3/PFKFB3/NUP62/NUP160/NUP214/SLC2A6/ME1/P2RX7/NUPR1/PGAM1/PDK2/EIF6/ZBTB7A/NUP85/HIF1A/SEH1L/INSR/NUP43/GSTZ1/POM121/COQ3/PFKFB4/PPARGC1A/SLC25A12/PRKAG2/MYOG/NCOR1/PFKFB1/NUP88/HDAC4/NUP107/PDK1/DDIT4/PFKFB2/ARNT/PDP2/PPARA/NUP93/PRKAA1/PSEN1/NUP205/NUP50/IFNG/PRKAG1/OGT/PDP1/ESRRB/ZBTB20/ME2/APP/SNCA/PDPR/POM121C/AAAS	58
BP	GO:0050688	regulation of defense response to virus	47/7096	73/18670	4.346e-06	0.0001921	0.0001432	PARP9/TNFAIP3/BIRC2/FGL2/STAT1/IL15/DDX60/ERCC6/LILRB1/AIM2/ELMOD2/SIN3A/TSPAN32/DDX58/TRAF3/IL1B/DHX9/MMP12/APOBEC3G/MAVS/PUM2/DTX3L/NPLOC4/SEC14L1/TARBP2/ANKRD17/BIRC3/HTRA1/IL12RB1/PCBP2/IFIT1/ZMPSTE24/C1QBP/MUL1/GPATCH3/RIOK3/HERC5/TRIM15/NLRX1/IL12B/TRAF3IP1/TRIM6/EIF2AK4/RNF216/TSPAN6/ZCCHC3/IL23A	47
BP	GO:0010506	regulation of autophagy	164/7096	327/18670	4.391e-06	0.0001928	0.0001437	ATP6V0D2/HTR2B/BMF/NAMPT/ATG7/PINK1/CTSA/TSC1/DRAM2/C9orf72/STAT3/TPCN1/GNAI3/GAPDH/RNF41/ATP6V1C1/CISD2/FEZ2/ULK2/FBXW7/DHRSX/UCHL1/SEC22B/LAMP3/PSAP/HMOX1/ATP6V0C/NUPR1/TRIM13/ERCC4/GSK3B/TICAM1/CHMP4B/SH3BP4/CSNK2A2/CDC37/WDR24/EXOC1/ITPR1/HGF/HIF1A/TRIM22/HSPB1/ATG101/LEP/ZKSCAN3/TAB3/TFEB/IKBKG/MCL1/HTRA2/PTPN22/TP53INP2/QSOX1/SPTLC2/CDK5/PLK2/CASP3/KLHL22/ABL1/ATP6V1A/RAB3GAP1/LAMTOR1/KAT8/DAPK1/RRAGD/ATG13/HMGB1/NPRL3/RAB8A/SIRT1/GPSM1/ATP6V1B2/MLST8/LRRK2/EIF4G2/FLCN/ATP6V1D/PTK2/ATM/SNX6/WDR6/PHF23/PRKAG2/BCL2L11/PLK3/KAT5/VPS13D/LAMTOR4/MAPK8/EPM2A/TRIM21/UBQLN2/MEFV/BCL2/NEDD4/ATP6V0E2/RAB39B/MFSD8/PRKACA/RAB5A/ADRB2/FOXK2/USP30/SREBF2/FZD5/ATP6V1G2/CPTP/RRAGA/ZMPSTE24/DNM1L/VDAC1/EEF1A2/LAMTOR5/ULK1/MUL1/USP10/ABL2/MID2/SESN1/PRKAA1/MTMR3/SNX5/SH3GLB1/IFT20/SMCR8/NPRL2/FBXL2/BAD/EIF4G1/TREM2/DAP/EXOC4/IFNG/PRKAG1/TRIM65/MTMR9/DAPL1/SCFD1/CLEC16A/RNF5/LACRT/OPTN/MTDH/EIF2AK4/VPS26B/MTOR/PIM2/ERN1/DAPK2/SNCA/ATP6V1B1/MET/DRAM1/LZTS1/HMGB4/SESN2/SLC38A9/CAPNS1/FOXO3/SNX32/PIK3CB/PRKAB1/KDM4A	164
BP	GO:1903706	regulation of hemopoiesis	228/7096	475/18670	4.433e-06	0.0001933	0.0001441	FOS/SIGLEC15/PNP/CCR2/NFKBIZ/PTPN6/LILRB2/DLL1/ANXA1/SPI1/LYN/IRF7/ZFP36/NOTCH2/IRF1/SOD1/EGR3/ATP6AP1/STAT3/PIM1/PTPN2/KLF10/PSMB9/SOX13/RNF41/BCL6/NLRP3/SH3RF1/LILRB3/SMAD7/SLC46A2/DUSP10/PSMB8/KITLG/CIB1/CD2/FGL2/FBXW7/STAT1/MYC/IL4R/CEBPB/DPY30/CBFB/NFE2/PTPRC/LDB1/IL15/PSMA5/ADAM8/TNF/PSMD11/PAF1/CD74/NFKBIA/MOV10/TESC/PRELID1/PSME1/LILRB1/KAT2B/IL7R/HCLS1/AXL/FAM210B/EIF6/TGFB1/SIN3A/LMO2/HIF1A/SOCS5/PSMB10/PTK2B/PSMA1/PSMA4/ROR2/METTL3/LILRB4/TRAF6/ZBTB1/FLT3LG/TLR4/ZBTB7B/TCF12/DTX1/ABL1/NFKBID/CASP8/PSMB1/PSMC4/AGER/GPR171/RASGRP1/CLPTM1/MITF/PIK3R6/PSMD13/ISG15/HMGB1/CREB1/IL7/PSMB3/TNFRSF18/TYROBP/TESPA1/HLA-G/TOX/TFE3/KLF13/ACVR1B/CYLD/CR1/FLCN/TAL1/CTLA4/PSMB5/PSMD6/ETS1/PSMC3/FNIP1/KMT2E/VNN1/TMEM64/NRARP/N4BP2L2/PSME3/BMP4/PSMC6/HMGB2/CYP26B1/NFATC2/ID2/DPF2/NME1/CNOT4/LAG3/AGO1/OSM/PPP2R3C/INHBA/IL12RB1/TNRC6B/LGALS9/TNRC6A/PGLYRP4/EVI2B/BTN2A2/RAB7B/MMP14/HES1/ADA/ARNT/LEO1/HLX/PIAS3/NFE2L2/EIF2AK2/IL18/FADD/AP3B1/SCIN/ATXN1L/TNFSF4/NFAM1/SART1/KAT2A/DCSTAMP/LRRC17/PSMC1/SOCS1/BAD/ZFP36L2/TREM2/C1QC/PSMD8/PSMA2/IFNG/NR4A3/CLDN18/FANCD2/CSF3R/PCID2/CD4/RB1/TLR3/INHA/IL12B/PSMC5/DROSHA/MEIS1/PSMC2/KMT2B/PRKCZ/PSMB2/PSMD4/CD80/TBX21/MTOR/PRKCQ/FOXP1/RHOA/FOXN1/CDC73/FANCA/SLC9B2/CD83/CCL19/IKZF3/MALT1/PUS7/ZBTB16/PSMD1/TRIM58/PRMT1/PSMB4/HOXA7/PRKCA/SLAMF8/IL23A/PSMD9/WDR5/PSMD3/HLA-DOA/APCS/FOXO3/THPO/MEF2C/L3MBTL1	228
BP	GO:0071902	positive regulation of protein serine/threonine kinase activity	167/7096	334/18670	4.543e-06	0.0001968	0.0001467	IGF1/HTR2B/NOD2/S100A12/FPR1/SLC27A1/FAM20A/PEA15/ATP2B4/DUSP6/PPP2CA/WNT5A/DUSP5/CSK/SOD1/ERP29/FLT1/CCND3/CD40/KITLG/MIF/MAP2K1/CIB1/ALS2/DUSP7/RGCC/JAK2/MAP3K8/PTPRC/P2RX7/MAGED1/ALK/UBE2N/ADAM8/DVL2/TNF/EZH2/CD74/AKAP13/ERCC6/PKD2/KRAS/ZEB2/MAP3K4/CCND2/MAPKAPK3/PSRC1/HIGD1A/TGFB1/TAOK3/GADD45B/HGF/ARRB1/PAK1/RAPGEF2/MAP4K5/PTK2B/SYAP1/ROR2/INSR/TAB3/ETAA1/NRG1/TRAF6/IKBKG/TLR4/DBF4B/FLT3/PDGFC/TPD52L1/BMP2/VEGFA/HRAS/IL1B/PARP16/CSPG4/AGER/MAP3K12/RASGRP1/MDFIC/SHC1/PIK3R6/TNFRSF11A/PDE6G/CRK/RAF1/SIRT1/CCND1/DUSP19/MAP4K2/MAP4K3/MLST8/PDGFB/LRRK2/FGF1/DDX3X/PROK1/MAPKAPK5/TAB1/ADORA2B/MAPKAPK2/BMP4/CDKN1B/CCNK/MAP3K6/MAP4K1/DAZAP2/LPAR3/ADRB2/MLKL/UBC/MAP2K2/MAP3K11/PDGFA/FZD5/BIRC7/LPAR1/MAP3K5/PROK2/F2R/MOS/CDK5R2/CEMIP/EIF2AK2/EGFR/MUL1/CCNY/ADAM17/TRAF2/FZD4/ADAM9/SPRY2/PRKAA1/PSEN1/MAPK1/TELO2/MAP2K4/CCNYL1/TGFB3/MAP3K13/IFNG/MAPK11/RET/MAP3K1/HSP90AB1/MAP2K5/PIK3CG/CSF1R/CCNT1/RHOA/ERN1/SNCA/PDCD10/CCL19/CCNYL2/GHR/STRADA/DAXX/CD24/TLR6/PDGFD/GHRL/FZD10/PIK3CB/NRK/SASH1/MAP3K9	167
BP	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	124/7096	237/18670	4.659e-06	0.0002005	0.0001495	MYD88/HTR2B/NOD2/S100A12/FYN/TRIM32/CX3CR1/BCL10/PINK1/TNIP2/DDX21/WNT5A/NUP62/FLNA/TNFAIP3/RHOC/CD40/DDRGK1/BIRC2/WLS/STAT1/SQSTM1/NLRP12/SHISA5/GSTP1/UBE2N/TNF/CD74/HMOX1/AKAP13/GPRC5B/TRIM13/TICAM1/REL/RELA/IRAK4/TRIM22/HSPB1/CD36/TLE1/TAB3/TRAF6/MAPKBP1/IKBKG/TLR4/PLK2/ABL1/TNFSF10/NFKBID/CASP8/IL1B/S100B/MIER1/S100A4/ATP2C1/TRADD/RBCK1/IL1RN/SIRT1/MAVS/S100A13/IFIT5/EDA/APOL3/ZDHHC13/ASH1L/EDAR/TNIP1/TGM2/ANKRD17/CTH/BIRC3/ROR1/TNIP3/LGALS1/DDX1/CASP1/ZMYND11/ALPK1/LGALS9/LPAR1/F2R/SLC20A1/RHOH/TNFRSF10B/MUL1/USP10/GOLT1B/SECTM1/FADD/MID2/TRAF2/CPNE1/RIOK3/TMED4/TIFA/TRAF5/CAPN3/RORA/UBE2I/SLC44A2/CD4/NLRX1/TLR3/OPTN/MTDH/LIME1/RHOA/PIM2/CX3CL1/TSPAN6/ZFAND6/CCL19/MALT1/TIRAP/CHUK/CCR7/PELI2/GJA1/NR1H4/NLRC3/TLR6/CXXC5/IL37	124
BP	GO:0070665	positive regulation of leukocyte proliferation	79/7096	139/18670	4.856e-06	0.0002075	0.0001547	IGF1/PNP/CCR2/LILRB2/ANXA1/CDKN1A/BST1/LYN/CD55/BCL6/CD40/KITLG/MIF/PTPRC/IL15/CD74/CD320/TICAM1/CCDC88B/LEP/TNFSF13B/CORO1A/TRAF6/FLT3LG/TLR4/HLA-DPB1/HLA-DPA1/HLA-E/NCK1/CD209/SLC39A10/IL1B/AIF1/AGER/CCL5/RASAL3/HLA-DMB/ICOSLG/HMGB1/EFNB1/IGFBP2/IL7/IL6ST/IL6/IRS2/PDCD1LG2/BCL2/NFATC2/CLCF1/CD1D/IL12RB1/CD274/LGALS9/EBI3/HES1/ADA/IL18/FADD/CD276/TFRC/TNFSF4/CHRNB2/TNFRSF4/HAVCR2/SPTA1/CD4/TNFRSF13C/IL12B/CD80/PRKCQ/GPR183/CCL19/TIRAP/CD3E/ATAD5/CD24/IL23A/MEF2C/ZNF335	79
BP	GO:0006469	negative regulation of protein kinase activity	123/7096	235/18670	4.958e-06	0.0002105	0.0001569	ITPRIP/PTPN6/DUSP1/PRKAR2B/CDKN2D/CDKN1A/SOCS3/DUSP6/LYN/PPP2CA/FABP4/DUSP5/PTPN2/NUP62/CHP1/DUSP10/TNFAIP3/CIB1/RGS2/UCHL1/DUSP7/GSTP1/PTPRC/IRAK3/EPHB2/TESC/APOE/HMGCR/KAT2B/DUSP3/LRP5/HEXIM1/TAOK3/GADD45B/CBLB/GNAQ/DUSP18/SOCS5/HSPB1/ZFYVE28/HEG1/PRKCD/LATS1/PKIB/GMFG/ZGPAT/HYAL2/MBIP/DUSP2/TFAP4/PTPN22/ADARB1/CEBPA/DUS2/IGF1R/NCK1/CDKN2B/CASP3/SFN/NPM1/ABL1/PAK2/IL1B/DTNBP1/MVP/PTK6/CDKN1C/PAQR3/SH3BP5L/PPM1F/SIRT1/HEXIM2/BMP7/DUSP19/SMYD3/SNX6/DUSP14/RGS3/DUSP4/PRKAG2/TARBP2/BMP4/INPP5K/RGS14/CDKN1B/CDKN2C/TSG101/TRIB2/AKT1S1/CD300A/GSKIP/LAX1/SPRY1/CORO1C/VPS25/SPRED1/CAV3/CHORDC1/SPRY2/DVL1/DEPTOR/PSEN1/IPO7/SMCR8/SOCS1/IFNG/HIPK3/FGFR1OP/LATS2/DNAJA1/SMPD1/RB1/MEN1/YWHAG/PKIA/GPS1/ITGB1BP1/PDCD4/ADAR/AIDA/CEP85/TAF7/PTPRJ	123
BP	GO:0042033	chemokine biosynthetic process	15/7096	16/18670	5.095e-06	0.0002135	0.0001592	WNT5A/AZU1/EGR1/TNF/CD74/HMOX1/TICAM1/IL1B/AGER/IL6/IL18/SIGIRR/IFNG/TLR3/APP	15
BP	GO:0050755	chemokine metabolic process	15/7096	16/18670	5.095e-06	0.0002135	0.0001592	WNT5A/AZU1/EGR1/TNF/CD74/HMOX1/TICAM1/IL1B/AGER/IL6/IL18/SIGIRR/IFNG/TLR3/APP	15
BP	GO:0032655	regulation of interleukin-12 production	37/7096	54/18670	5.246e-06	0.0002184	0.0001628	TLR2/ACP5/CLEC7A/IRF1/LILRA5/CD40/IRAK3/NFKB1/LILRB1/SLAMF1/RELA/CD36/TRAF6/TLR4/CMKLR1/IDO1/AGER/HMGB1/HLA-G/TIGIT/MEFV/CD47/LGALS9/PLCB1/IRF8/C1QBP/TNFSF4/TLR8/IFNG/MAPK11/TLR3/IL12B/FOXP1/CCL19/TIRAP/CCR7/IL23A	37
BP	GO:0006006	glucose metabolic process	111/7096	209/18670	5.89e-06	0.0002437	0.0001817	IGF1/HK3/PDK4/FBP1/PGK1/MDH1/PTPN2/PFKM/PFKP/GAPDH/PPARD/GALM/PMAIP1/ADIPOR1/SIK1/SLC45A3/COX11/PER2/SLC37A4/TNF/GSK3B/KAT2B/PGAM1/ATF4/LRP5/PKM/PDK2/DYRK2/TPI1/IGFBP4/PCK2/LEP/PPP1R3E/AKR1A1/INSR/PPP1R3D/ALDOC/DDB1/ENO1/OMA1/ALDOA/SLC25A10/SLC35B4/ACACB/CRTC2/SIRT1/NISCH/GPI/DGAT2/IRS2/G6PD/DUSP12/PPARGC1A/ALDH5A1/MLYCD/NLN/GNB3/LCMT1/SERP1/CREM/SLC25A12/PGM2/PGM5/KHK/PFKFB1/INPP5K/PPP1R3B/PDK1/PPP1R3F/CPT1A/PDX1/PDHB/FOXK2/SORD/GOT2/PGK2/PFKFB2/ZMPSTE24/DLAT/NFE2L1/SERPINA12/PPP1CA/MST1/FABP5/PPARA/SLC25A13/KAT2A/PRKAA1/PDHA2/ENO2/BAD/GAA/RORA/OGT/PPP1CB/ESRRB/PC/ADPGK/MTOR/GDPGP1/GCG/PFKL/INPPL1/SESN2/RBP4/C1QTNF3/WDR5/G6PC/FAM3A/GHRL/NKX1-1	111
BP	GO:0032722	positive regulation of chemokine production	39/7096	58/18670	5.974e-06	0.0002456	0.0001831	TRIM32/TLR2/CLEC7A/WNT5A/AZU1/MBP/MIF/IL4R/EGR1/TNF/CD74/HMOX1/TICAM1/HIF1A/FFAR2/TLR4/IL1B/AIF1/AGER/LRP1/IL7/MAVS/IL6/DDX3X/ALOX15B/ADORA2B/LGALS9/MCOLN2/EIF2AK2/ADAM17/HAVCR2/TSLP/IFNG/TLR3/LBP/CSF1R/TRPV4/APP/TIRAP	39
BP	GO:0005996	monosaccharide metabolic process	148/7096	292/18670	6.081e-06	0.0002471	0.0001842	FUCA1/IGF1/TALDO1/HK3/PDK4/FBP1/PGK1/MDH1/AKR1B1/SLC23A2/PTPN2/PFKFB3/PFKM/PFKP/GAPDH/PPARD/GALM/PMAIP1/ADIPOR1/ALDH1A1/SIK1/CRYL1/SLC45A3/COX11/PER2/SLC2A3/SLC37A4/GALE/FUT4/TNF/GSK3B/FUT7/KAT2B/PGAM1/ATF4/LRP5/PKM/PDK2/DYRK2/GALK1/RPE/TPI1/TKT/MAN2A2/IGFBP4/MAN2B1/PCK2/LEP/PPP1R3E/AKR1A1/DHDH/INSR/CYB5A/PPP1R3D/ALDOC/DDB1/RPIA/FGGY/ENO1/OMA1/GCLC/GSTO1/ALDOA/PMM2/SLC25A10/SLC35B4/ACACB/CRTC2/SIRT1/NISCH/GPI/DGAT2/IRS2/G6PD/PFKFB4/FPGT/DUSP12/PPARGC1A/ALDH5A1/MLYCD/NLN/GNB3/LCMT1/SERP1/CREM/SLC25A12/PGM2/PGM5/KHK/PFKFB1/INPP5K/PPP1R3B/NUDT5/PDK1/PPP1R3F/CPT1A/PDX1/PDHB/FUT6/GALT/FOXK2/SORD/CYB5R3/GOT2/PGK2/PFKFB2/ZMPSTE24/DLAT/NFE2L1/SERPINA12/PPP1CA/MST1/FABP5/PPARA/SLC25A13/KAT2A/PRKAA1/PDHA2/ENO2/BAD/GAA/FUCA2/RORA/OGT/PGD/PPP1CB/ESRRB/PC/ADPGK/MTOR/B4GALT1/GLYCTK/GDPGP1/SLC35A2/GCG/MAN2B2/ABHD10/PFKL/INPPL1/SESN2/RBP4/C1QTNF3/WDR5/G6PC/FAM3A/GHRL/NKX1-1/RBKS	148
BP	GO:0002697	regulation of immune effector process	220/7096	458/18670	6.087e-06	0.0002471	0.0001842	ITGAM/NOD2/CCR2/RAC2/NFKBIZ/PTPN6/IL27RA/ANXA1/SERPINB9/STX7/APPL2/GRN/BCL10/LYN/MAD2L2/CD55/PARP9/DDX21/WNT5A/STAT6/PROS1/TMBIM6/TNFRSF14/BCL6/NLRP3/SMAD7/DUSP10/TNFAIP3/CD40/CD1C/MIF/BIRC2/FGL2/STAT1/IL4R/PTPRC/IL15/P2RX7/CD1E/A2M/HFE/LAMP1/CD59/TNF/DDX60/IRAK3/CD74/HMOX1/C12orf4/GPRC5B/ERCC6/LILRB1/AIM2/TICAM1/CD22/IL7R/CD226/ELMOD2/TGFB1/PPP3CB/STXBP1/SIN3A/IL18R1/PTAFR/FFAR2/SOCS5/CD36/STXBP2/LEP/CFP/FAM49B/HLA-F/TRAF6/ZBTB1/CLC/TSPAN32/IL20RB/TLR4/DDX58/ZBTB7B/FGR/TRAF3/ABR/HLA-E/HLA-B/RSAD2/NFKBID/IL1B/CLEC12B/FBXO38/AGER/RASGRP1/DHX9/CD1B/RAP1A/MMP12/PIK3R6/HLA-DMB/HMGB1/CRK/CLU/TRPM4/IL1R1/GPI/HLA-G/APOBEC3G/DNASE1/SERPING1/MAVS/IL6/CR1/CD5L/PUM2/HLA-C/CFHR4/BCR/VSIG4/DTX3L/RPS19/C3AR1/CD96/NPLOC4/SEC14L1/ADORA2B/FCER2/MLH1/TARBP2/PARP3/ANKRD17/CD47/CLCF1/BIRC3/UNC13D/PVR/LAG3/DDX1/CR2/HTRA1/CD1D/IL12RB1/CD1A/PCBP2/CD300A/LGALS9/IFIT1/PGLYRP4/FER/C1R/RABGEF1/FZD5/ZMPSTE24/HLX/ULBP2/CRTAM/C1QBP/VAV1/MUL1/KIR2DL4/IL18/FADD/GPATCH3/TRAF2/TFRC/TNFSF4/AP1G1/RIOK3/IL13RA2/HERC5/CFB/APOA1/PRAM1/TNFRSF4/C1QC/CD84/TGFB3/CPN1/HLA-A/HAVCR2/IFNG/NCR3/NR4A3/SERPINB4/EXOSC3/TRIM15/NLRX1/TLR3/SNX4/LBP/IL12B/SH2D1A/TRAF3IP1/TRIM6/EIF2AK4/MICA/PRKCZ/CD80/TBX21/NCR1/IL18RAP/C5AR2/APLF/RNF216/EXOSC6/TSPAN6/CCL19/MALT1/CD244/FOXF1/WAS/PAXIP1/ATAD5/CFHR5/APPL1/ZCCHC3/SLAMF8/IL23A/RBP4/CXCL6/PTPRJ/C7	220
BP	GO:0007015	actin filament organization	195/7096	400/18670	6.311e-06	0.0002546	0.0001898	MYADM/S100A10/CDC42EP4/VASP/EZR/PTGER4/RAC2/DPYSL3/PLS1/ARF6/STMN1/MAD2L2/FHOD1/TSC1/C9orf72/ARAP1/DIAPH1/SORBS3/HCK/RHOBTB1/PLEKHG2/ITGB5/NEDD9/FLNA/RHOC/S1PR1/ACTN4/PSTPIP1/RGCC/JAK2/TPM3/TMSB10/SPIRE1/SLC9A1/IQGAP2/ARHGEF10L/ACTR2/CXCL12/MICAL1/RND3/TMOD3/LIMA1/HCLS1/GAS7/EVL/TWF2/RDX/PFN1/CDC42EP2/ARRB1/ARHGAP25/PAK1/MARCKS/PHACTR1/PTK2B/CFL2/CAPZA2/SWAP70/PRKCD/SRF/ACTN1/LATS1/GMFG/CORO1A/RHOG/BAIAP2/ARFGEF1/CAPG/MICAL2/CAP1/ACTC1/DIAPH2/NCK1/PSTPIP2/ABL1/FCHSD1/CCDC155/MYBPC3/ALDOA/AIF1/ARPC1A/ARHGEF2/CAPZA1/PPM1F/MKKS/SH3BP1/RAC1/ARPIN/SPTBN1/ARPC1B/KPTN/CDC42EP3/CYFIP1/MYO1C/RHOU/CORO1B/ARHGAP6/ARHGAP12/BBS4/LIMCH1/ZYX/ARF1/TPM4/ARPC5L/LCP1/EMP2/NRP1/FSCN3/COTL1/BCL2/TPM1/AVIL/ERMN/INPP5K/MICALL2/CD47/PLS3/RHOQ/CFL1/KANK1/TRIOBP/ARHGAP18/ADD3/RHOV/TTC17/GRB2/PLEK/JMY/ACTR3B/SHANK1/FER/SEMA5A/RHOF/CD2AP/LPAR1/DMTN/CORO1C/ACTR3/RHOH/PXN/MSRB1/CLASP2/EFS/LMOD3/CAV3/BIN3/SCIN/HSP90B1/PREX1/SLIT2/MYOM2/CCL26/FSCN1/APOA1/ARPC4/TGFB3/RUFY3/RHOBTB3/SPTA1/SPTBN2/SYNPO2L/TACSTD2/ENAH/TMEFF2/WIPF1/ARPC2/KANK3/MTOR/CAP2/RHOA/TRPV4/PICK1/CX3CL1/ITGB1BP1/SNX9/MET/SHROOM1/ESPNL/CCR7/WAS/ROCK2/RHOBTB2/CCL24/ACTA1/INPPL1/ASAP3/SHANK3/SERPINF2/BIN1/NCKAP1/FCHSD2/ALMS1/GHRL/SYNPO/FMN1	195
BP	GO:0044262	cellular carbohydrate metabolic process	145/7096	286/18670	7.371e-06	0.0002955	0.0002203	IGF1/MYOF/CBFA2T3/HK3/PDK4/SLC5A3/FBP1/ENOSF1/EXTL2/GNPTG/MANBA/NDST2/AKR1B1/HS2ST1/MGAM/STAT3/PTPN2/PFKFB3/B3GNT8/PMAIP1/ADIPOR1/SIK1/SLC45A3/COX11/PER2/GK/IMPAD1/EXT2/NUPR1/EXT1/INPP1/GSK3B/AGL/KAT2B/PGAM1/PDK2/DYRK2/GALK1/RPE/TPI1/B3GNT2/PTAFR/IGFBP4/PTK2B/PCK2/NAGK/LEP/PPP1R3E/SYNJ1/INSR/GYS1/P2RY6/PPP1R3D/GYG2/GNPTAB/DDB1/CSGALNACT1/FGGY/B3GNT5/PPP1R2/PPIP5K2/SLC35B4/ACACB/COQ3/IDH1/SYNJ2/SIRT1/PHKB/IL6ST/DGAT2/IDUA/OCRL/IRS2/PFKFB4/DUSP12/PPARGC1A/PCDH12/PHKG1/MLYCD/IDH2/NLN/GNB3/LCMT1/GUSB/SLC25A12/PGM2/PRKAG2/MYOG/KHK/PFKFB1/GK5/INPP5K/IMPA2/HDAC4/PPP1R3B/NDST1/PDK1/PPP1R3F/CSGALNACT2/MTMR2/PLEK/FOXK2/B4GALT5/SORD/DDIT4/PFKFB2/ZMPSTE24/NFE2L1/SERPINA12/PPP1CC/PPP1CA/MST1/PPARA/IPPK/KAT2A/B3GNT4/BAD/GAA/RORA/PYGM/OGT/PGD/PPP1CB/PYGL/ESRRB/GNE/MTOR/SNCA/B4GALT1/CD244/GCG/ABHD10/ADCYAP1R1/TREH/SESN2/C1QTNF3/WDR5/P2RY1/G6PC/FAM3A/NTSR1/NKX1-1/INPP5A/IMPA1/RBKS	145
BP	GO:0032642	regulation of chemokine production	51/7096	82/18670	7.565e-06	0.0003014	0.0002247	KLF4/TRIM32/TLR2/CLEC7A/WNT5A/AZU1/ARG2/MBP/MIF/IL4R/GSTP1/EGR1/TNF/CD74/HMOX1/TICAM1/HIF1A/FFAR2/SOCS5/TLR4/IL1B/AIF1/AGER/LRP1/IL7/MAVS/IL6/DDX3X/ALOX15B/ADORA2B/MEFV/LGALS9/MCOLN2/EIF2AK2/MUL1/ADAM17/SIGIRR/TREM2/HAVCR2/TSLP/IFNG/TLR3/MAP2K5/LBP/CSF1R/TRPV4/APP/TIRAP/NR1H4/C1QTNF3/CXCL6	51
BP	GO:0070482	response to oxygen levels	192/7096	394/18670	7.642e-06	0.0003026	0.0002256	SLC8A1/EPAS1/CBFA2T3/KCNMB1/TLR2/NAMPT/CDKN1A/LDHA/ATG7/NR4A2/PINK1/RBPJ/PGK1/AIFM1/LMNA/TSC1/ATP6AP1/TMBIM6/CAPN2/VEGFB/PTGS2/PSMB9/PDLIM1/PPARD/GNB1/PMAIP1/PSMB8/SIRT4/BIRC2/ACTN4/AHCY/MYC/RGCC/CYB5R4/FAS/EGR1/PSMA5/ADAM8/PSMD11/HMOX1/SLC9A1/PSME1/CXCL12/DPP4/SUV39H2/ATF4/PKM/SLC2A8/CDK4/HIGD1A/TGFB1/ITPR1/ALAD/FIS1/HIF1A/PAK1/PSMB10/PTK2B/LEP/PSMA1/PSMA4/ADAM15/SRF/LOXL2/RYR1/ASCL2/BMP2/VEGFA/EGLN1/CAT/CASP3/ATP6V1A/ENO1/PSMB1/UCP2/PSMC4/AGTRAP/S100B/AGER/PML/PSMD13/CREB1/RAF1/PSMB3/SIRT1/BMP7/NDRG1/HIF1AN/PLOD1/EGLN3/PPARGC1A/CITED2/PSEN2/PSMB5/PSMD6/ETS1/ARNT2/ATM/MIR34A/PSMC3/HDAC2/PAM/PLK3/COX4I2/POLG/SUV39H1/PSME3/BCL2/XRCC1/SCAP/PSMC6/ATP1B1/CDKN1B/CPEB1/PLOD2/ITGA2/PDK1/UBC/CYBA/CYBB/KCNK2/DDIT4/MMP14/LPAR1/ADA/ARNT/STUB1/DNM1L/CHRNA4/NFE2L2/PPARA/ADAM17/DNMT3A/HSP90B1/AQP3/MALAT1/ACAA2/PRKAA1/MDM2/CHRNB2/PSMC1/ERCC2/CUL2/BAD/TGFB3/CHCHD2/PSMD8/RORA/TBL2/PSMA2/ATP7A/BACH1/CLCA1/HYOU1/PIN1/OPRD1/CD34/SCFD1/CCNA2/CACNB3/PSMC5/MMP2/TERT/PSMC2/POLB/PSMB2/PSMD4/ND4/MTOR/KCNMA1/RHOA/PICK1/RBX1/P2RX2/TM9SF4/USP19/PSMD1/SLC8A3/ROCK2/ENDOG/PSMB4/ALDH3A1/UCN3/CD24/MGARP/PSMD9/PSMD3/CPEB2/FOXO3/PLEKHN1/MIR146A/FUNDC1	192
BP	GO:0006096	glycolytic process	67/7096	115/18670	8.037e-06	0.0003163	0.0002358	IGF1/CBFA2T3/HK3/LDHA/FBP1/PGK1/STAT3/PFKFB3/NUP62/NUP160/PFKM/PFKP/GAPDH/NUP214/SLC2A6/P2RX7/NUPR1/PGAM1/PKM/GALK1/EIF6/TPI1/ZBTB7A/NUP85/HIF1A/SEH1L/INSR/ALDOC/NUP43/ENO1/ALDOA/POM121/OGDH/GPI/PFKFB4/PPARGC1A/DHTKD1/PRKAG2/MYOG/NCOR1/PFKFB1/NUP88/HDAC4/NUP107/FOXK2/DDIT4/PGK2/PFKFB2/ARNT/PPARA/NUP93/PRKAA1/PSEN1/NUP205/ENO2/SLC4A1/NUP50/IFNG/PRKAG1/OGT/ESRRB/ZBTB20/ADPGK/APP/PFKL/POM121C/AAAS	67
BP	GO:0009124	nucleoside monophosphate biosynthetic process	110/7096	208/18670	8.346e-06	0.0003265	0.0002434	IGF1/CBFA2T3/HK3/UPP1/LDHA/PINK1/FBP1/PGK1/VPS9D1/STAT3/PFKFB3/NUP62/NUP160/PFKM/PFKP/GAPDH/NUP214/SLC2A6/P2RX7/NUPR1/AK3/PGAM1/AK2/PKM/GALK1/EIF6/TPI1/ZBTB7A/TGFB1/GMPS/DGUOK/NUP85/HIF1A/SEH1L/ADK/INSR/ALDOC/CDADC1/PAICS/NUP43/IMPDH1/ENO1/DNAJC30/ALDOA/CMPK1/TK1/POM121/RFK/OGDH/GPI/PFKFB4/PPARGC1A/FLCN/DHTKD1/SLC25A12/LDHC/PRKAG2/MYOG/NCOR1/PFKFB1/ATIC/NUP88/HDAC4/NUP107/PRPS1/PPAT/TYMS/FOXK2/DDIT4/AMPD2/PGK2/PFKFB2/ADA/DCK/ARNT/SHMT1/UCK1/PPARA/NUP93/SLC25A13/TK2/PRKAA1/PSEN1/NUP205/ENO2/PID1/DCTD/SLC4A1/PRPS1L1/TREM2/CAD/NUP50/IFNG/PRKAG1/OGT/PRPS2/ESRRB/ZBTB20/VCP/ADPGK/UCKL1/TAZ/APP/UPP2/AMPD3/LHPP/DUT/PFKL/POM121C/AAAS	110
BP	GO:0045080	positive regulation of chemokine biosynthetic process	12/7096	12/18670	9.035e-06	0.0003513	0.0002619	WNT5A/AZU1/EGR1/TNF/CD74/HMOX1/TICAM1/IL1B/AGER/IFNG/TLR3/APP	12
BP	GO:0002576	platelet degranulation	73/7096	128/18670	9.274e-06	0.0003563	0.0002656	IGF1/SERPINA1/FN1/F5/TAGLN2/LYN/SOD1/PROS1/VEGFB/CDC37L1/POTEKP/FLNA/CYB5R1/ACTN4/PPBP/LAMP2/VCL/PSAP/A2M/TLN1/TGFB1/CHID1/STXBP1/PHACTR2/SCCPDH/HGF/MAGED2/CD36/STXBP2/ACTN1/FAM49B/CD63/CFD/ENDOD1/HABP4/QSOX1/VEGFA/TEX264/ALDOA/CLU/SERPING1/PCYOX1L/PDGFB/SPARC/SCG3/P2RX1/SERPINE1/TIMP1/TUBA4A/SYTL4/PLEK/PDGFA/VWF/NHLRC2/DMTN/A1BG/SRGN/APOA1/VTI1B/TGFB3/CTSW/HRG/LHFPL2/TMX3/TOR4A/ABCC4/MANF/APP/APOOL/SERPINF2/ITIH3/ALB/CD109	73
BP	GO:0032606	type I interferon production	73/7096	128/18670	9.274e-06	0.0003563	0.0002656	MYD88/TRIM32/TLR2/IRF7/IRF1/STAT6/TNFAIP3/NLRC5/STAT1/FLOT1/NFKB1/LILRB1/TICAM1/REL/RELA/NMI/LRRFIP1/DTX4/NFKB2/TLR4/DDX58/PTPN22/TRAF3/CACTIN/UBE2L6/RELB/XRCC5/PLCG2/DHX9/MMP12/POLR2L/ISG15/HMGB1/MAVS/CYLD/POLR2H/DDX3X/AZI2/NPLOC4/IFIH1/TRIM21/HMGB2/OTUD5/YY1/PCBP2/POLR1C/ZBP1/POLR2F/GPATCH3/POLR3E/TAX1BP1/TLR8/POLR2K/RIOK3/HERC5/XRCC6/HAVCR2/TRIM15/PIN1/NLRX1/TLR3/TRAF3IP1/ZBTB20/POLR3F/RNF216/TIRAP/POLR3GL/CHUK/ZCCHC3/HMGB4/NLRC3/POLR3K/RNF135	73
BP	GO:0002708	positive regulation of lymphocyte mediated immunity	62/7096	105/18670	9.568e-06	0.0003654	0.0002724	STX7/MAD2L2/STAT6/NLRP3/CD40/CD1C/PTPRC/P2RX7/CD1E/LAMP1/TNF/CD226/TGFB1/IL18R1/FAM49B/HLA-F/TRAF6/ZBTB1/HLA-E/HLA-B/RSAD2/IL1B/FBXO38/RASGRP1/CD1B/IL1R1/HLA-G/IL6/HLA-C/FCER2/MLH1/CLCF1/PVR/LAG3/CD1D/IL12RB1/CD1A/FZD5/ULBP2/CRTAM/VAV1/KIR2DL4/IL18/FADD/TRAF2/TFRC/TNFSF4/AP1G1/HLA-A/NCR3/EXOSC3/IL12B/SH2D1A/MICA/PRKCZ/TBX21/IL18RAP/EXOSC6/MALT1/PAXIP1/ATAD5/IL23A	62
BP	GO:0032479	regulation of type I interferon production	72/7096	126/18670	9.697e-06	0.0003681	0.0002744	MYD88/TRIM32/TLR2/IRF7/IRF1/STAT6/TNFAIP3/NLRC5/STAT1/FLOT1/NFKB1/LILRB1/TICAM1/REL/RELA/NMI/LRRFIP1/DTX4/NFKB2/TLR4/DDX58/PTPN22/TRAF3/CACTIN/UBE2L6/RELB/XRCC5/PLCG2/DHX9/MMP12/POLR2L/ISG15/HMGB1/MAVS/CYLD/POLR2H/DDX3X/NPLOC4/IFIH1/TRIM21/HMGB2/OTUD5/YY1/PCBP2/POLR1C/ZBP1/POLR2F/GPATCH3/POLR3E/TAX1BP1/TLR8/POLR2K/RIOK3/HERC5/XRCC6/HAVCR2/TRIM15/PIN1/NLRX1/TLR3/TRAF3IP1/ZBTB20/POLR3F/RNF216/TIRAP/POLR3GL/CHUK/ZCCHC3/HMGB4/NLRC3/POLR3K/RNF135	72
BP	GO:0036293	response to decreased oxygen levels	181/7096	370/18670	1.029e-05	0.0003885	0.0002896	SLC8A1/EPAS1/CBFA2T3/KCNMB1/TLR2/NAMPT/LDHA/NR4A2/PINK1/RBPJ/PGK1/AIFM1/LMNA/TSC1/TMBIM6/CAPN2/VEGFB/PTGS2/PSMB9/PDLIM1/PPARD/GNB1/PMAIP1/PSMB8/SIRT4/BIRC2/ACTN4/AHCY/MYC/RGCC/EGR1/PSMA5/ADAM8/PSMD11/HMOX1/SLC9A1/PSME1/CXCL12/DPP4/SUV39H2/ATF4/PKM/SLC2A8/HIGD1A/TGFB1/ITPR1/ALAD/FIS1/HIF1A/PAK1/PSMB10/PTK2B/LEP/PSMA1/PSMA4/ADAM15/SRF/LOXL2/RYR1/ASCL2/BMP2/VEGFA/EGLN1/CAT/CASP3/ENO1/PSMB1/UCP2/PSMC4/AGTRAP/S100B/AGER/PML/PSMD13/CREB1/RAF1/PSMB3/SIRT1/BMP7/NDRG1/HIF1AN/PLOD1/EGLN3/PPARGC1A/CITED2/PSEN2/PSMB5/PSMD6/ETS1/ARNT2/ATM/MIR34A/PSMC3/PAM/PLK3/COX4I2/SUV39H1/PSME3/BCL2/XRCC1/SCAP/PSMC6/ATP1B1/CDKN1B/CPEB1/PLOD2/ITGA2/PDK1/UBC/CYBA/CYBB/KCNK2/DDIT4/MMP14/ADA/ARNT/STUB1/DNM1L/CHRNA4/NFE2L2/PPARA/ADAM17/DNMT3A/HSP90B1/AQP3/MALAT1/ACAA2/PRKAA1/MDM2/CHRNB2/PSMC1/ERCC2/CUL2/BAD/TGFB3/CHCHD2/PSMD8/RORA/TBL2/PSMA2/ATP7A/BACH1/CLCA1/HYOU1/PIN1/OPRD1/CD34/SCFD1/CCNA2/CACNB3/PSMC5/MMP2/TERT/PSMC2/PSMB2/PSMD4/ND4/MTOR/KCNMA1/RHOA/PICK1/RBX1/P2RX2/TM9SF4/USP19/PSMD1/SLC8A3/ROCK2/ENDOG/PSMB4/ALDH3A1/UCN3/CD24/MGARP/PSMD9/PSMD3/CPEB2/FOXO3/PLEKHN1/MIR146A/FUNDC1	181
BP	GO:0032675	regulation of interleukin-6 production	84/7096	152/18670	1.096e-05	0.0004113	0.0003066	MYD88/NOD2/KLF2/TLR1/TLR2/PTPN6/IL27RA/LILRB2/CLEC7A/WNT5A/CSK/SYT11/STAT3/CAPN2/LILRA5/TNFAIP3/BANK1/MBP/LILRA2/NLRP12/CEBPB/P2RX7/TNF/IRAK3/CD74/IL1RAP/SLAMF1/TICAM1/HGF/ARRB1/PTAFR/SOCS5/CD36/MAPK13/TRAF6/HYAL2/TLR4/DDX58/PTPN22/IL1B/AIF1/AGER/DHX9/ARHGEF2/HMGB1/IL1RN/TYROBP/MAVS/SIGLEC16/IL6/CD200R1/IFIH1/ADORA2B/MAPKAPK2/CD47/LGALS9/CYBA/RABGEF1/RAB7B/F2R/TNFSF4/TLR8/TREM2/HAVCR2/TSLP/NLRX1/TLR3/LBP/ZBTB20/TRPV4/C5AR2/APP/CX3CL1/TIRAP/AKIRIN2/HMGB4/NR1H4/NLRC3/TLR6/C1QTNF3/IL17RC/GHRL/IL37/MIR146A	84
BP	GO:0051650	establishment of vesicle localization	146/7096	290/18670	1.109e-05	0.0004138	0.0003085	SERPINA1/F5/APBA1/PINK1/STX11/DNM3/RAP1B/SYT11/MCFD2/BLOC1S2/BBS5/RAB11A/KLHL12/MLPH/ACTN4/CTSC/SEC22B/P2RX7/CTBP2/CD59/GSK3B/ANKRD28/KIF3B/STXBP1/UNC13B/KIFAP3/GRIPAP1/SAR1B/TRAPPC6A/MYO5A/SYNJ1/CSNK1D/PPP6R1/FAM91A1/WDR11/IKBKG/CNIH3/ITGA4/FBXL20/AP3M2/TRAPPC5/CDK5/TRAK2/PAFAH1B1/ASIP/CTSZ/RAB3GAP1/ARFGAP3/TMEM230/TMED10/DTNBP1/CLN3/RASGRP1/RAP1A/C17orf75/STARD3NL/BLOC1S6/WIPI1/BET1/BBS2/DOC2B/MKKS/MAP4K2/PREPL/GOSR2/AP1M2/LRRK2/GOSR1/MYO1C/STX5/ADCY1/SAR1A/BBS4/ARF1/PPP6C/TOR1A/DNM1/P2RX1/TRAPPC6B/ADORA2B/VPS18/TRAPPC9/NAPA/DNM2/TBC1D20/BLOC1S3/COL7A1/DCTN2/RAB5A/KIAA1107/NDEL1/BBS7/GPR143/KIF13A/LMAN1/PEF1/CAMK2A/CHRM2/YKT6/DNM1L/BLOC1S1/CHRNA4/BLOC1S4/CLASP2/SEC23IP/TRAPPC2L/AP3B1/ATP2A2/DVL1/PSEN1/CEP19/FMR1/TRAPPC3/RAB3A/CHRNB2/P2RY4/PPFIA3/SYT9/EXOC4/KIF1B/AP3M1/SYT1/KIF5B/TRAK1/SCFD1/SYT2/VAMP1/DOC2A/SNAP29/SYT4/PRKCZ/CADPS2/SYT5/MREG/KIF1C/CDH3/SNCA/RIMS2/WNT7A/PICALM/PREB/SEC24A/RAB27A/P2RY1/SEC16B/TRIM46	146
BP	GO:0072525	pyridine-containing compound biosynthetic process	83/7096	150/18670	1.156e-05	0.0004288	0.0003197	IGF1/CBFA2T3/HK3/NAMPT/QPRT/LDHA/FBP1/PARP9/PGK1/STAT3/PFKFB3/NUP62/NUP160/PFKM/PTGS2/PFKP/GAPDH/NUP214/NMNAT3/SLC2A6/P2RX7/NUPR1/PGAM1/PKM/GALK1/EIF6/TPI1/ZBTB7A/NUP85/HIF1A/SEH1L/INSR/ALDOC/NUP43/NMNAT1/ENO1/IDO1/ALDOA/PARP16/NADK2/POM121/OGDH/GPI/PFKFB4/PPARGC1A/IDH2/KYNU/HAAO/DHTKD1/PRKAG2/MYOG/NCOR1/PFKFB1/NUP88/HDAC4/NUP107/NMRK2/FOXK2/NMNAT2/DDIT4/PGK2/PFKFB2/ARNT/PPARA/NUP93/IDO2/SLC5A8/PRKAA1/PSEN1/NUP205/ENO2/SLC4A1/NUP50/IFNG/PRKAG1/OGT/ESRRB/ZBTB20/ADPGK/APP/PFKL/POM121C/AAAS	83
BP	GO:0006757	ATP generation from ADP	67/7096	116/18670	1.2e-05	0.0004424	0.0003298	IGF1/CBFA2T3/HK3/LDHA/FBP1/PGK1/STAT3/PFKFB3/NUP62/NUP160/PFKM/PFKP/GAPDH/NUP214/SLC2A6/P2RX7/NUPR1/PGAM1/PKM/GALK1/EIF6/TPI1/ZBTB7A/NUP85/HIF1A/SEH1L/INSR/ALDOC/NUP43/ENO1/ALDOA/POM121/OGDH/GPI/PFKFB4/PPARGC1A/DHTKD1/PRKAG2/MYOG/NCOR1/PFKFB1/NUP88/HDAC4/NUP107/FOXK2/DDIT4/PGK2/PFKFB2/ARNT/PPARA/NUP93/PRKAA1/PSEN1/NUP205/ENO2/SLC4A1/NUP50/IFNG/PRKAG1/OGT/ESRRB/ZBTB20/ADPGK/APP/PFKL/POM121C/AAAS	67
BP	GO:0002705	positive regulation of leukocyte mediated immunity	75/7096	133/18670	1.223e-05	0.0004486	0.0003345	ITGAM/NOD2/STX7/MAD2L2/DDX21/STAT6/NLRP3/CD40/CD1C/IL4R/PTPRC/P2RX7/CD1E/LAMP1/TNF/TICAM1/CD226/TGFB1/STXBP1/IL18R1/PTAFR/FAM49B/HLA-F/TRAF6/ZBTB1/DDX58/FGR/HLA-E/HLA-B/RSAD2/IL1B/FBXO38/RASGRP1/CD1B/IL1R1/HLA-G/MAVS/IL6/HLA-C/ADORA2B/FCER2/MLH1/CLCF1/PVR/LAG3/DDX1/CD1D/IL12RB1/CD1A/FZD5/ULBP2/CRTAM/VAV1/KIR2DL4/IL18/FADD/TRAF2/TFRC/TNFSF4/AP1G1/HLA-A/NCR3/EXOSC3/SNX4/IL12B/SH2D1A/MICA/PRKCZ/TBX21/IL18RAP/EXOSC6/MALT1/PAXIP1/ATAD5/IL23A	75
BP	GO:0042752	regulation of circadian rhythm	66/7096	114/18670	1.249e-05	0.0004531	0.0003378	ARNTL2/CIPC/ATG7/BHLHE40/KLF10/FBXW7/SIK1/PER2/MAGED1/EZH2/GSK3B/THRAP3/SUV39H2/UBE3A/SIN3A/GNAQ/CSNK1D/RBM4/DDB1/RBM4B/USP9X/PSPC1/KDM2A/SRRD/NR1D2/PML/CREB1/SFPQ/PPARGC1A/FBXL3/CRTC1/ADCY1/CREM/CSNK1E/SUV39H1/MAPK8/ID2/NR1H3/OPN3/TIMELESS/HNRNPD/ADA/KCNA2/PPP1CC/PPP1CA/PPARA/CLOCK/USP7/PRKAA1/CHRNB2/RORA/ARNTL/PPP1CB/PER3/OPRL1/MTOR/GHRH/ROCK2/TARDBP/NR2F6/GNA11/SIAH2/TOP2A/OPN4/GHRL/MAPK9	66
BP	GO:0007031	peroxisome organization	50/7096	81/18670	1.254e-05	0.0004531	0.0003378	PEX11A/TMEM135/HMGCL/PEX12/ACAA1/PHYH/PEX11G/SCP2/MPV17/PEX16/FIS1/ABCD3/ECH1/UBE2D3/UBE2D2/USP9X/CAT/AGPS/ACOX1/ECI2/SLC27A2/HSD17B4/IDH1/ACOX2/MAVS/DAO/DECR2/MLYCD/NUDT19/PEX13/TYSND1/PEX3/UBC/PEX19/EHHADH/DNM1L/RAB8B/NUDT7/PEX14/PEX11B/ACOX3/GNPAT/CROT/ABCD1/ZFAND6/HACL1/HAO1/SEC16B/ACOT8/PIPOX	50
BP	GO:0045073	regulation of chemokine biosynthetic process	14/7096	15/18670	1.261e-05	0.0004531	0.0003378	WNT5A/AZU1/EGR1/TNF/CD74/HMOX1/TICAM1/IL1B/AGER/IL6/SIGIRR/IFNG/TLR3/APP	14
BP	GO:0014002	astrocyte development	31/7096	44/18670	1.264e-05	0.0004531	0.0003378	S100A8/FPR2/DLL1/GRN/VIM/LAMB2/TNF/KRAS/MIR142/LAMC3/ROR2/TLR4/EIF2B5/IL1B/AGER/LDLR/LRP1/TTBK1/IL6/BACE2/ROR1/CNTF/IFNGR1/EGFR/PSEN1/TREM2/IFNG/APP/TSPAN2/PLP1/SMO	31
BP	GO:0007265	Ras protein signal transduction	214/7096	448/18670	1.283e-05	0.0004575	0.0003411	IGF1/SH2B2/RTN4R/CDC42EP4/RAB9A/RAC2/CDKN1A/ARF6/STMN1/LYN/RALGDS/FBP1/NOTCH2/CDC42SE1/DOK2/ARHGEF18/RAP1B/RASGEF1A/NUP62/RHOBTB1/PLEKHG2/SPATA13/RASGRP2/CYTH4/MYO9B/TIMP2/BCL6/RAB11A/GNB1/RHOC/ARHGEF3/KITLG/RASGRP3/FLOT1/DENND1A/ALS2/SQSTM1/G3BP2/P2RY8/JAK2/CYTH1/FGD6/RRAS/FGD5/SHOC2/ZNF304/EPHB2/AKAP13/ARHGDIA/RAPGEF6/KRAS/APOE/ARHGEF10L/RAB31/RND3/PLD1/ARHGEF40/RDX/RAB23/CDC42EP2/ARRB1/RAPGEF2/KCTD10/HEG1/RAP2C/RAB24/USP28/NRG1/RHOG/ARFGEF1/STMN3/CDC42SE2/ITSN1/EPOR/ABR/NET1/ARHGDIB/RASA2/PLK2/HRAS/ABL1/ARHGEF6/OPHN1/ABCA1/GDI1/RAP2B/CTNNAL1/AIF1/IQSEC1/RHOT2/RASGRP1/ARHGEF2/RAP1A/RAB20/RASAL3/SHC1/CRK/RAB8A/RAF1/FBXO8/NISCH/RAB43/RAC1/RAB33B/RAB29/MAPRE2/LPAR6/KALRN/IRS2/CDC42EP3/RAB32/CYFIP1/FLCN/RAB38/RHOU/DOK1/STK19/ARHGAP6/BCR/MAPKAPK5/RASA3/SCAI/NRP1/RIT1/DNM2/RAB5C/RAB39B/RHOQ/CFL1/NRAS/RAB5A/KANK1/SETDB1/GPR18/SYNGAP1/RHOV/RANGRF/GRB2/OBSCN/KSR2/RABGEF1/RHOF/RAB7B/ITGA3/LPAR1/SPRY1/F2R/RHOH/HACE1/RASGRF1/ELMO1/RAB8B/VAV1/GPSM2/ABL2/IQSEC2/PREX1/ITSN2/SPRY2/RALGPS1/RAB22A/RAB3A/GNA13/GPR35/RAB35/APOA1/STAMBP/RASAL1/ARHGEF37/IQSEC3/FGD3/RHOBTB3/MAPK11/OGT/MAPKAP1/ARHGEF17/RAB3B/IFT22/RB1/CCNA2/PHACTR4/SYNPO2L/FGD4/PSD4/DENND4B/EPS8L2/MAP4K4/P2RY10/RHOA/RAB33A/RAB3D/SHC3/MET/CHUK/ARHGEF4/KPNB1/WAS/ROCK2/RHOBTB2/GPR20/RFXANK/MCF2L/ARFGAP1/RAB27A/RAB26/RAB36/MMD2/KIF14/NCKAP1/ARHGEF9/PSD3/RASGRP4/LAT/RAB28	214
BP	GO:0016051	carbohydrate biosynthetic process	112/7096	214/18670	1.291e-05	0.0004579	0.0003414	IGF1/TALDO1/FBP1/PGK1/EXTL2/MDH1/NDST2/AKR1B1/HS2ST1/PTPN2/MGAT2/B3GNT8/GAPDH/SIK1/PER2/SLC37A4/IMPAD1/EXT2/EXT1/NFKB1/GSK3B/AGL/CHST13/KAT2B/PGAM1/ATF4/PDK2/DYRK2/TPI1/TGFB1/B3GNT2/TKT/PTAFR/PTK2B/PCK2/LEP/PPP1R3E/AKR1A1/INSR/GYS1/P2RY6/PPP1R3D/GYG2/ALDOC/DDB1/CSGALNACT1/B3GNT5/ENO1/ALDOA/ST3GAL2/SLC25A10/CHST11/SLC35B4/CRTC2/SIRT1/GPI/DGAT2/IRS2/PDGFB/G6PD/PPARGC1A/PHKG1/CHST14/NLN/SLC25A12/PGM2/PFKFB1/INPP5K/IMPA2/PPP1R3B/NDST1/PPP1R3F/CSGALNACT2/PLEK/FOXK2/B4GALT5/SORD/GOT2/PGK2/AP2A1/SERPINA12/PPP1CA/MST1/PPARA/SLC25A13/ST6GALNAC5/KAT2A/B3GNT4/ENO2/OGT/PGD/CHST12/PPP1CB/ST6GALNAC6/ESRRB/PC/MTOR/B3GALT5/SNCA/B4GALT1/CD244/GCG/ADCYAP1R1/SESN2/RBP4/C1QTNF3/WDR5/P2RY1/G6PC/FAM3A/NTSR1/IMPA1	112
BP	GO:0031334	positive regulation of protein complex assembly	136/7096	268/18670	1.313e-05	0.000463	0.0003451	CDC42EP4/VASP/BMF/CLEC7A/ARF6/PINK1/HCK/RHOBTB1/PMAIP1/RHOC/G3BP2/TNF/SPIRE1/GBP5/IQGAP2/ERCC4/GSK3B/ACTR2/AIM2/EVL/PSRC1/TGFB1/PFN1/CDC42EP2/UNC13B/PAK1/CD36/CLIP1/PTK2B/RPA1/SRF/GMFG/CORO1A/BAIAP2/CXCL13/DDB1/TLR4/NCK1/VEGFA/FCHSD1/CDK5RAP2/ABCA1/PSMC4/ARPC1A/MITF/P2RY12/MAPRE1/SUB1/CREB1/CLU/TPPP3/RAC1/ARPIN/TTBK1/ARPC1B/CDC42EP3/CDH5/CYFIP1/MYO1C/TAL1/SUMO1/CORO1B/ATM/ARF1/SETX/GTF2H4/PSMC3/FNIP1/ARPC5L/LCP1/BCL2L11/CAND1/BAX/PSMC6/ERCC1/CDKN1B/MMP3/GRB2/PLEK/JMY/MMP1/ACTR3B/FER/STUB1/ACTR3/MED25/LMOD3/ATR/CAV3/SCIN/CDH17/MPP7/CCL26/FSCN1/DDB2/SH3GLB1/MSN/ERCC2/EIF4G1/ARPC4/HNF1B/BCLAF1/FOSL1/IFNG/HNF1A/SKAP1/SLAIN2/CUL4B/PPP2R5B/PSMC5/ARPC2/PSMC2/VCP/MTOR/NAV3/RHOA/PICK1/SNX9/RBX1/MET/ASAP1/CCR7/WAS/PAXIP1/ICE1/RHOBTB2/WNT10B/CCL24/SPIDR/TPPP/TLR6/BIN1/NCKAP1/FCHSD2/MAPK9/FMN1	136
BP	GO:0002285	lymphocyte activation involved in immune response	97/7096	181/18670	1.362e-05	0.0004772	0.0003557	PTGER4/NFKBIZ/IL27RA/DLL1/ANXA1/APBB1IP/MAD2L2/NOTCH2/SLC11A1/TSC1/CLEC4D/STAT6/STAT3/BCL6/NLRP3/CLEC4E/SMAD7/CD40/CD1C/LFNG/FGL2/LY9/IL4R/PTPRC/LAMP1/BATF/DOCK10/LILRB1/TGFB1/IL18R1/UNG/SOCS5/PTK2B/ITGAL/SWAP70/HLA-F/CORO1A/SEMA4A/TLR4/ZBTB7B/RELB/ABL1/NFKBID/PLCG2/ITM2A/HLA-DMB/HMGB1/IL6/LCP1/MLH1/PARP3/ERCC1/CLCF1/CCR6/UNC13D/LGALS1/IFNK/IL12RB1/LGALS9/LIG4/PGLYRP4/ADA/HLX/ITFG2/IL18/DOCK11/CDH17/TFRC/TNFSF4/AP1G1/PSEN1/EXO1/RORA/HAVCR2/PLCL2/IFNG/ATP7A/EXOSC3/TNFSF18/GAPT/IL12B/EIF2AK4/PRKCZ/CD80/TBX21/MTOR/FOXP1/APLF/GPR183/EXOSC6/CCL19/MALT1/CD244/PAXIP1/ATAD5/RAB27A/IL23A	97
BP	GO:0016054	organic acid catabolic process	139/7096	275/18670	1.375e-05	0.0004772	0.0003557	ASRGL1/HEXB/QPRT/ATP2B4/ALDH3A2/HADHB/ENOSF1/HIBADH/ARG2/IL4I1/PPARD/CHP1/PCYOX1/HADH/HMGCL/GNPDA1/ACAA1/NPL/AHCY/CD44/CRYL1/ALDH7A1/PHYH/PHYKPL/BCKDK/ALDH6A1/SLC9A1/PCBD1/SCP2/HAL/DDAH2/HNMT/HEXA/FAH/ETFA/CPT2/TGFB1/AUH/ABCD3/PCK2/NAGK/LEP/AKR1A1/ECH1/ACADM/DBT/HYAL2/ACADS/DECR1/RENBP/MTRR/IDO1/GSTZ1/MCEE/AIG1/PLA2G15/ACOX1/ETFDH/ECI2/SLC27A2/HSD17B4/QDPR/ACACB/OGDH/ACOX2/ALDH4A1/ACBD5/ACADSB/GLUD1/IDUA/PCYOX1L/IRS2/BDH2/DAO/ADHFE1/ABHD3/DECR2/ALDH5A1/MLYCD/MCCC1/KYNU/HAAO/GUSB/SHMT2/GLUD2/TST/PCCB/ECI1/MPST/HSD17B10/CYP26B1/ALDH8A1/CTH/NUDT19/ETFB/PEX13/TYSND1/PPAT/CPT1A/EHHADH/HYAL3/SORD/ACADVL/GLS/GOT2/HADHA/AGXT2/SHMT1/CEMIP/NUDT7/PPARA/ACAA2/IDO2/AMT/ACOX3/BCKDHB/AMDHD1/STAB2/PGD/BCAT2/ALDH1L1/CYP26A1/BCKDHA/CROT/LYVE1/MTOR/HYKK/CYP4F3/ABCD1/ABHD16A/HMGCLL1/ABHD10/HACL1/TDO2/SESN2/MAT1A/HAO1/ACOT8/PIPOX	139
BP	GO:0046395	carboxylic acid catabolic process	139/7096	275/18670	1.375e-05	0.0004772	0.0003557	ASRGL1/HEXB/QPRT/ATP2B4/ALDH3A2/HADHB/ENOSF1/HIBADH/ARG2/IL4I1/PPARD/CHP1/PCYOX1/HADH/HMGCL/GNPDA1/ACAA1/NPL/AHCY/CD44/CRYL1/ALDH7A1/PHYH/PHYKPL/BCKDK/ALDH6A1/SLC9A1/PCBD1/SCP2/HAL/DDAH2/HNMT/HEXA/FAH/ETFA/CPT2/TGFB1/AUH/ABCD3/PCK2/NAGK/LEP/AKR1A1/ECH1/ACADM/DBT/HYAL2/ACADS/DECR1/RENBP/MTRR/IDO1/GSTZ1/MCEE/AIG1/PLA2G15/ACOX1/ETFDH/ECI2/SLC27A2/HSD17B4/QDPR/ACACB/OGDH/ACOX2/ALDH4A1/ACBD5/ACADSB/GLUD1/IDUA/PCYOX1L/IRS2/BDH2/DAO/ADHFE1/ABHD3/DECR2/ALDH5A1/MLYCD/MCCC1/KYNU/HAAO/GUSB/SHMT2/GLUD2/TST/PCCB/ECI1/MPST/HSD17B10/CYP26B1/ALDH8A1/CTH/NUDT19/ETFB/PEX13/TYSND1/PPAT/CPT1A/EHHADH/HYAL3/SORD/ACADVL/GLS/GOT2/HADHA/AGXT2/SHMT1/CEMIP/NUDT7/PPARA/ACAA2/IDO2/AMT/ACOX3/BCKDHB/AMDHD1/STAB2/PGD/BCAT2/ALDH1L1/CYP26A1/BCKDHA/CROT/LYVE1/MTOR/HYKK/CYP4F3/ABCD1/ABHD16A/HMGCLL1/ABHD10/HACL1/TDO2/SESN2/MAT1A/HAO1/ACOT8/PIPOX	139
BP	GO:0042180	cellular ketone metabolic process	127/7096	248/18670	1.428e-05	0.0004929	0.0003674	NQO1/ATP2B4/PDK4/ANXA1/APPL2/STARD4/CBR4/SRD5A1/AKR1B1/OAZ2/PTGS2/PSMB9/ADIPOR1/PSMB8/SIRT4/PANK2/RDH10/SLC45A3/APOC1/EGR1/PSMA5/PSMD11/SLC7A11/CD74/ELOVL5/AKR1C3/HMGCR/PSME1/LPGAT1/AKR7A2/PDK2/EIF6/TPI1/DHRS9/SLC7A7/COQ7/COQ5/PSMB10/PSMA1/PNKD/PSMA4/AKR1A1/NR1H2/ERLIN1/OAZ3/BMP2/AKR1C1/IDO1/PSMB1/GSTZ1/IL1B/ODC1/PSMC4/PDSS1/ERLIN2/ACACB/PSMD13/COQ3/HAGH/PSMB3/SIRT1/DGAT2/FABP3/IRS2/PPARGC1A/MLYCD/KYNU/APOA5/PSMB5/PSMD6/OXCT1/PSMC3/PRKAG2/BMP5/PSME3/SIRT5/CBR3/SCAP/PSMC6/ALDH8A1/NR1H3/COQ10B/BHMT/COQ9/PDK1/TYSND1/CPT1A/COQ6/AZIN1/ACADVL/GOT2/AKR1B10/NFE2L1/INSIG1/PDP2/FABP5/BRCA1/PPARA/IDO2/ADIPOR2/KDSR/HSD17B3/PSMC1/PSMD8/PSMA2/NR4A3/PDP1/PSMC5/PSMC2/PSMB2/PSMD4/MTOR/SNCA/COQ10A/COQ4/ABCD1/CYP2W1/ATCAY/PDPR/PSMD1/CYP46A1/PSMB4/CACNA1H/TDO2/NR1H4/PSMD9/PSMD3	127
BP	GO:0060759	regulation of response to cytokine stimulus	101/7096	190/18670	1.441e-05	0.0004949	0.0003689	KLF4/TRIM32/TLR2/PTPN6/IL1R2/SOCS3/IRF7/PARP9/WNT5A/PTPN2/TNFAIP3/NLRC5/BIRC2/CREBRF/STAT1/CBFB/JAK2/GSTP1/PTPRC/TNF/IRAK3/CD74/YTHDF3/VRK2/IFNGR2/AXL/CDC37/UBE2K/HIF1A/MAPK7/NR1H2/METTL3/SPPL2A/IKBKG/TLR4/DDX58/CACTIN/PAFAH1B1/CASP8/SAMHD1/CCL5/DHX9/MMP12/CD300LF/RNF113A/SPATA2/IL7/TRADD/RBCK1/IL1RN/IL1R1/MAVS/ELF1/IL6/CYLD/LSM14A/SUMO1/OTUD4/SPHK1/IFIH1/BIRC3/NR1H3/CASP1/RNASEL/RFFL/ZBP1/RABGEF1/HIPK1/TRAF1/IFNGR1/CNOT7/MUL1/FADD/ADAM17/TRAF2/CASP4/SLIT2/CPNE1/TAX1BP1/SIGIRR/APOA1/SOCS1/TREM2/IL3/TSLP/IFNG/JAK1/TXK/PALM3/HSP90AB1/MAP2K5/IFNAR2/TRIM6/AGPAT1/CLIP3/ADAR/CHUK/AGPAT2/NR1H4/CD24/SLIT3	101
BP	GO:0002683	negative regulation of immune system process	220/7096	463/18670	1.513e-05	0.0005165	0.0003851	TSC22D3/CCR2/EZR/PTGER4/PTPN6/IL27RA/LILRB2/DLL1/DUSP1/ANXA1/SERPINB9/GRN/BCL10/LYN/CD55/ZFP36/IRF1/GRAMD4/GBP1/ARG2/GPNMB/MNDA/LST1/STAT6/PTPN2/TMBIM6/TNFRSF14/BCL6/LPXN/LILRB3/SMAD7/DUSP10/TNFAIP3/BANK1/NLRC5/KITLG/MIF/CIB1/FGL2/FBXW7/LY96/LGR4/MYC/LILRA2/IL4R/CEBPB/CBFB/PTPRC/LDB1/A2M/HFE/CD59/TNF/IRAK3/PAF1/CD74/NFKBIA/YTHDF3/HMOX1/TNFRSF21/LILRB1/CXCL12/TICAM1/DUSP3/CD22/IL7R/AXL/NMI/TGFB1/PPP3CB/SOCS5/PTK2B/PSMA1/NR1H2/METTL3/HLA-F/LILRB4/TSPAN32/IL20RB/TLR4/PTPN22/ZBTB7B/SOCS6/ABR/HLA-E/DTX1/CASP3/CACTIN/IDO1/NFKBID/CLEC12B/SAMHD1/GPR171/LDLR/MMP12/CD300LF/HMGB1/CRK/TYROBP/HLA-DOB/HLA-G/MFHAS1/SERPING1/ELF1/KLF13/TAPBPL/CD200R1/CR1/TAL1/CTLA4/GLMN/BCR/CST7/OTUD4/ATM/MIR34A/TIGIT/VSIG4/RPS19/SCGB1A1/PDCD1LG2/CD96/NRARP/BMP5/NPLOC4/SEC14L1/N4BP2L2/TARBP2/BMP4/PARP3/ID2/CD47/DPF2/NME1/NR1H3/LAG3/GPR18/INHBA/HTRA1/PCBP2/CD300A/CD274/RHBDD3/LGALS9/LAX1/PGLYRP4/FER/GCSAM/RABGEF1/BTN2A2/CNR2/AMBP/RAB7B/HES1/ADA/LEO1/HLX/PIAS3/NFE2L2/PLCB1/C1QBP/CXCR2/CNOT7/MUL1/KIR2DL4/FADD/GPATCH3/TNFRSF13B/SLIT2/TNFSF4/RIOK3/IL13RA2/MERTK/LRRC17/PAG1/APOA1/SOCS1/C1QC/CD84/TGFB3/HAVCR2/PLCL2/CLDN18/SERPINB4/NLRX1/TLR3/INHA/IL12B/SLA2/TRAF3IP1/MEIS1/MICA/GPX1/CD80/TBX21/C5AR2/TYRO3/CDC73/CX3CL1/TSPAN6/ADAR/TRAFD1/ZBTB16/FOXF1/PRMT1/PDCD1/APPL1/PSMB4/GREM1/HOXA7/NLRC3/TWSG1/SLAMF8/TLR6/UBASH3A/FAM3A/HLA-DOA/APCS/PTPRJ/PHPT1	220
BP	GO:0050729	positive regulation of inflammatory response	84/7096	153/18670	1.53e-05	0.0005198	0.0003875	MYD88/S100A9/S100A8/NOD2/S100A12/CCR2/TLR2/PTGER4/NFKBIZ/CLEC7A/GRN/FABP4/WNT5A/IL17RA/PTGS2/LILRA5/CTSC/NLRP12/CEBPB/MGST2/PLA2G7/JAK2/IL15/ADAM8/TNF/NFKBIA/GPRC5B/NUPR1/GBP5/TICAM1/MIR142/FFAR2/MAPK13/HYAL2/NAPEPLD/TLR4/CEBPA/HLA-E/IDO1/IL1B/LDLR/DHX9/TNFRSF11A/TRADD/IL6ST/TTBK1/IL6/LRRK2/ETS1/RPS19/GPSM3/ADORA2B/TNIP1/TGM2/C2CD4B/SERPINE1/CD47/ITGA2/OSM/TLR10/EGFR/IL18/CLOCK/TNFSF4/TREM2/IL17B/TSLP/SUCNR1/TLR3/PIK3CG/SNX4/LBP/IL12B/TRPV4/SNCA/CX3CL1/PDCD4/CCR7/APPL1/CCL24/IL17RB/IL23A/TLR6/IL17RC	84
BP	GO:0009116	nucleoside metabolic process	70/7096	123/18670	1.548e-05	0.000523	0.0003899	TYMP/PNP/UPP1/GNAI3/ACPP/AHCY/RAN/AK3/NFS1/MPP1/HDDC3/GMPS/DGUOK/RAB23/APIP/NT5C/ADK/MBIP/CDADC1/GUK1/IMPDH1/CTPS2/MTRR/DPYD/ENOPH1/CMPK1/TK1/MOCS2/APOBEC3G/MACROD1/PRTFDC1/LRRK2/APOBEC3C/DNPH1/NME3/MTAP/APOBEC2/NME4/GTPBP1/GMPR2/ATIC/RHOQ/NME1/DERA/PRPS1/GAMT/PPAT/MOCS3/ADA/DCK/AHCYL2/AHCYL1/UCK1/TK2/APOBEC3B/PRPS1L1/CTPS1/CAD/PRPS2/CDA/RHOA/UCKL1/NT5C3A/ENPP4/NT5M/UPP2/AMPD3/ADAL/GIMAP7/OARD1	70
BP	GO:0007623	circadian rhythm	109/7096	208/18670	1.556e-05	0.000523	0.0003899	HEBP1/ARNTL2/HS3ST2/NAMPT/CIPC/NFIL3/ATG7/EGR3/SRD5A1/JUND/BHLHE40/NAGLU/KLF10/DBP/FBXW7/AHCY/SIK1/LGR4/PER2/ATF5/EGR1/MAGED1/EZH2/HNRNPR/GSK3B/THRAP3/SUV39H2/ATF4/UBE3A/CDK4/SIN3A/GNAQ/LEP/CSNK1D/METTL3/RBM4/DDB1/RBM4B/USP9X/PSPC1/RELB/KDM2A/SRRD/NR1D2/AHR/PML/TNFRSF11A/CREB1/SIRT1/SFPQ/KLF9/PPARGC1A/MYCBP2/FBXL3/CRTC1/ADCY1/PROK1/CREM/CSNK1E/SETX/HDAC2/NCOR1/SUV39H1/MYBBP1A/MAPK8/KDM8/SERPINE1/ID2/NR1H3/OPN3/CPT1A/TYMS/TIMELESS/HNRNPD/PRMT5/PROK2/ADA/KCNA2/PPP1CC/PPP1CA/EGFR/TPH2/PPARA/CLOCK/USP7/GFPT1/PRKAA1/CHRNB2/HNF1B/RORA/ARNTL/OGT/PPP1CB/PER3/OPRL1/MTOR/GHRH/TOP1/ROCK2/NRIP1/TARDBP/NR2F6/GNA11/SIAH2/TOP2A/OPN4/GHRL/NTRK2/MAPK9	109
BP	GO:0009144	purine nucleoside triphosphate metabolic process	168/7096	342/18670	1.566e-05	0.0005238	0.0003905	IGF1/CBFA2T3/HK3/LDHA/PINK1/FBP1/PGK1/VPS9D1/STAT3/PFKFB3/NUP62/NUP160/PFKM/UQCRC2/GNAI3/PFKP/GAPDH/SLC25A25/NUP214/SLC2A6/P2RX7/UQCR11/NDUFA8/NUPR1/RAN/AK3/PGAM1/AK2/PKM/GALK1/NFS1/EIF6/TPI1/ZBTB7A/NDUFC1/TGFB1/DGUOK/RAB23/NUP85/CLPX/HIF1A/NUDT1/ISCU/SEH1L/NDUFB11/ADK/INSR/ALDOC/MBIP/NDUFS3/GUK1/NUP43/IMPDH1/NDUFA3/NMNAT1/ATP6V1A/ENO1/DNAJC30/ALDOA/UQCC2/NDUFA11/PARG/SAMHD1/POM121/OGDH/CHCHD10/MOCS2/UQCR10/COX7C/GPI/ATP6V1B2/LRRK2/PFKFB4/PPARGC1A/FLCN/COX7A2L/DHTKD1/NME3/NDUFA4/SLC25A12/SHMT2/LDHC/NME4/PRKAG2/MYOG/NCOR1/COX4I2/NDUFA1/GTPBP1/PFKFB1/NUP88/HDAC4/ATP1B1/RHOQ/NME1/NUDT5/TEFM/COQ9/NUP107/COA6/COX15/NDUFA10/FOXK2/NDUFB1/DDIT4/NDUFB5/UQCRQ/PGK2/PFKFB2/MOCS3/ADA/ARNT/DNM1L/NDUFS1/SLC25A33/PPARA/NUP93/SLC25A13/NDUFB8/PRKAA1/PSEN1/DNAJC15/NUP205/ENO2/PID1/SURF1/NDUFB6/BAD/SLC4A1/TREM2/NUP50/IFNG/PRKAG1/OGT/ATP7A/NDUFB3/SDHA/ESRRB/ZBTB20/VCP/NDUFS7/ADPGK/NDUFV2/ND4/SDHD/RHOA/TAZ/APP/SNCA/UQCRB/ATP6V1B1/AMPD3/ABCD1/NDUFB2/SDHAF2/GIMAP7/MYH3/COX6C/ATP1A2/NUDT16/PFKL/CTNS/NDUFS2/POM121C/AAAS/FIGNL1/NDUFA7/COX7B	168
BP	GO:0033059	cellular pigmentation	34/7096	50/18670	1.629e-05	0.000542	0.000404	BLOC1S2/BBS5/RAB11A/HPS4/MLPH/ZEB2/TRAPPC6A/MYO5A/CD63/HPS1/ASIP/DTNBP1/VPS33A/BLOC1S6/ANKRD27/BBS2/MKKS/RAB32/RAB38/BBS4/BCL2/BLOC1S3/DCTN2/BBS7/GPR143/KIF13A/BLOC1S1/BLOC1S4/AP3B1/AP1G1/AP1M1/MREG/CDH3/RAB27A	34
BP	GO:0006109	regulation of carbohydrate metabolic process	108/7096	206/18670	1.655e-05	0.0005479	0.0004085	IGF1/CBFA2T3/PDK4/FBP1/STAT3/PTPN2/PFKFB3/NUP62/NUP160/PMAIP1/ADIPOR1/NUP214/SIK1/SLC45A3/COX11/SLC2A6/P2RX7/NUPR1/NFKB1/GSK3B/KAT2B/PGAM1/PDK2/DYRK2/EIF6/ZBTB7A/TGFB1/NUP85/HIF1A/PTAFR/SEH1L/IGFBP4/PTK2B/LEP/PPP1R3E/INSR/P2RY6/PPP1R3D/DDB1/NUP43/POM121/SLC35B4/ACACB/SIRT1/DGAT2/IRS2/PDGFB/PFKFB4/DUSP12/PPARGC1A/MLYCD/NLN/GNB3/LCMT1/SLC25A12/PRKAG2/MYOG/NCOR1/KHK/PFKFB1/NUP88/INPP5K/HDAC4/PPP1R3B/NUP107/PDK1/PPP1R3F/PLEK/FOXK2/DDIT4/PFKFB2/ZMPSTE24/ARNT/AP2A1/NFE2L1/SERPINA12/PPP1CA/MST1/PPARA/NUP93/KAT2A/PRKAA1/PSEN1/NUP205/BAD/RORA/NUP50/IFNG/PRKAG1/OGT/PPP1CB/ESRRB/ZBTB20/MTOR/APP/SNCA/CD244/GCG/ADCYAP1R1/SESN2/C1QTNF3/WDR5/P2RY1/POM121C/FAM3A/AAAS/NTSR1/NKX1-1	108
BP	GO:0043547	positive regulation of GTPase activity	195/7096	405/18670	1.674e-05	0.0005513	0.000411	S100A10/HTR2B/RTN4R/SIPA1L1/TBC1D24/WNT5A/TSC1/ARHGAP31/STARD8/VPS9D1/ARAP1/RASGRP2/MYO9B/NEDD9/ARAP3/S1PR1/CD40/ALDH1A1/ADPRH/STARD13/RGS2/RASGRP3/DENND1A/ALS2/RABGAP1L/AGFG1/F11R/RGS1/STXBP5/TBC1D15/DVL2/EZH2/DOCK10/ARHGDIA/RAPGEF6/FAM13A/GSK3B/ARHGEF10L/ASAP2/ARHGAP27/TBC1D5/DENND1B/DOCK8/ELMOD2/ARHGAP30/CDC42EP2/ARHGAP20/ARRB1/ARHGAP25/GNAQ/RAPGEF2/PTK2B/SGSM1/TBC1D1/ARHGAP19/RHOG/CXCL13/ARFGEF1/SNX18/ADRB1/ABR/NET1/ARHGDIB/RASA2/ARHGAP22/HRAS/ARHGEF6/SRGAP3/OPHN1/RGS12/RAB3GAP1/ARFGAP3/GDI1/RP2/ARHGAP26/IQSEC1/CCL5/GDI2/RASGRP1/RIN2/RAP1A/RASAL3/SEMA4D/TBC1D2/ANKRD27/TAGAP/RABGAP1/NPRL3/CRK/CCL7/TBCK/SH3BP1/AGAP4/ARHGAP24/MAPRE2/RGL3/KALRN/OCRL/LRRK2/FLCN/DOCK5/TBC1D12/ARHGAP6/BCR/ARHGAP12/RALGAPB/RGS3/SRGAP2/RASA3/CCL13/TBC1D17/NRP1/TBC1D9B/CCL8/TBC1D20/TBC1D13/BCAS3/RGS14/TBC1D8/SIPA1L3/ARHGAP18/ELMOD3/NDEL1/ACAP1/SNX13/SYNGAP1/TBC1D8B/RGS5/TBC1D7/EIF5/TBC1D22A/ZC3H15/CORO1C/F2R/DNM1L/RASGRF1/GARNL3/PLCB1/RABEP1/VAV1/GMIP/RCC2/CCL20/DOCK11/PREX1/CCL26/RALBP1/RUNDC1/NPRL2/RASAL1/ADAP1/TBC1D21/RGS20/NUP50/EVI5/LLGL1/PIN1/TBC1D10C/RALGAPA2/RIN1/ACAP3/AGAP3/RGS6/AGAP1/ALS2CL/CHN2/MAP4K4/SRGAP1/PRTN3/LIMS1/CX3CL1/ACAP2/DEPDC5/CHM/SNX9/GRTP1/RGS16/GRHL3/CCL19/SIPA1L2/RGP1/ADAP2/CCL4/ASAP1/RGS17/CCR7/PICALM/CCL24/SYDE1/PREB/ASAP3/SMAP2/ARFGAP1/TBC1D10B/FZD10	195
BP	GO:0042866	pyruvate biosynthetic process	68/7096	119/18670	1.694e-05	0.0005549	0.0004137	IGF1/CBFA2T3/HK3/LDHA/FBP1/PGK1/STAT3/PFKFB3/NUP62/NUP160/PFKM/PFKP/GAPDH/NUP214/SLC2A6/P2RX7/NUPR1/PGAM1/PKM/GALK1/EIF6/TPI1/ZBTB7A/NUP85/HIF1A/SEH1L/INSR/ALDOC/NUP43/ENO1/ALDOA/POM121/OGDH/GPI/PFKFB4/PPARGC1A/DHTKD1/PRKAG2/MYOG/NCOR1/PFKFB1/NUP88/HDAC4/NUP107/FOXK2/DDIT4/PGK2/PFKFB2/ARNT/PPARA/NUP93/PRKAA1/PSEN1/NUP205/ENO2/SLC4A1/SRR/NUP50/IFNG/PRKAG1/OGT/ESRRB/ZBTB20/ADPGK/APP/PFKL/POM121C/AAAS	68
BP	GO:0051289	protein homotetramerization	56/7096	94/18670	1.768e-05	0.0005762	0.0004296	PKD2L1/VASP/ACOT13/APPL2/FBP1/CBR4/MCOLN1/SYT11/ALDH9A1/PFKM/PFKP/ACPP/PCBD1/GBP5/PKD2/PKM/EVL/APIP/CBY1/RYR1/DECR1/CAT/ALDOA/SAMHD1/GPX3/TK1/ACACB/CRTC2/TRPM4/TRPM2/ALDH5A1/CRTC1/CRTC3/SHMT2/RXRA/USP16/CD247/HSD17B10/HINT3/CTH/PPAT/OSBPL2/GLS/DNM1L/SHMT1/PEX14/SRR/CDA/DCTPP1/PCBD2/ST13/CRYZ/HCN1/PFKL/TDO2/MAT1A	56
BP	GO:0016579	protein deubiquitination	142/7096	283/18670	1.808e-05	0.0005843	0.0004356	STAM/USP51/USP3/TNIP2/BARD1/JOSD1/PSMB9/NLRP3/SMAD7/TNFAIP3/OTUD6B/KEAP1/PSMB8/BIRC2/USP45/SMAD2/UCHL1/ENY2/MYC/KDM1B/USP54/PSMA5/RAD23B/PSMD11/NFKBIA/SKP2/WDR20/PSME1/KAT2B/ACTB/HIF1A/PSMB10/PSMA1/PSMA4/USP28/TRAF6/ATXN7L3/RUVBL1/IKBKG/UIMC1/DDX58/TRAF3/ZRANB1/USP46/USP9X/PSMB1/PSMC4/ADRM1/PSMD13/SPATA2/PSMB3/OTUD1/ATXN7/UCHL5/RCE1/CYLD/SUDS3/INO80C/TFPT/MBD5/MCRS1/PSMB5/PSMD6/OTUD4/USP4/PSMC3/ACTR5/SHMT2/IFIH1/TAB1/PSME3/USP16/USP31/TRIM21/TNIP1/PSMC6/USP26/OTUD5/YY1/DESI2/BIRC3/TNIP3/SENP8/ASXL2/USP1/ADRB2/CDC25A/HGS/STAMBPL1/UBC/FOXK2/USP30/FOXO4/USP27X/TOMM20/USP11/ATXN3/BRCA1/USP10/YOD1/TRAF2/USP7/USP35/KAT2A/MDM2/CCNA1/DDB2/STAMBP/PSMC1/TAF9B/CLSPN/USP49/PSMD8/UBXN1/PSMA2/OTUD3/OGT/BAP1/CDC20/CCNA2/INO80D/PSMC5/PSMC2/POLB/PSMB2/PSMD4/VCP/RHOA/USP22/BRCC3/USP19/PSMD1/TADA3/USP37/ACTL6A/ATXN3L/JOSD2/PSMB4/USP32/PSMD9/PSMD3/SIAH2	142
BP	GO:0070646	protein modification by small protein removal	149/7096	299/18670	1.811e-05	0.0005843	0.0004356	STAM/USP51/USP3/TNIP2/BARD1/JOSD1/PSMB9/NLRP3/SMAD7/TNFAIP3/OTUD6B/KEAP1/PSMB8/BIRC2/USP45/SMAD2/UCHL1/ENY2/MYC/KDM1B/USP54/PSMA5/RAD23B/SENP6/PSMD11/NFKBIA/SKP2/WDR20/PSME1/KAT2B/ACTB/HIF1A/PSMB10/PSMA1/PSMA4/USP28/TRAF6/ATXN7L3/RUVBL1/IKBKG/UIMC1/DDX58/TRAF3/ZRANB1/USP46/USP9X/PSMB1/PSMC4/ADRM1/PSMD13/SPATA2/PSMB3/OTUD1/ATXN7/UCHL5/RCE1/CYLD/SUDS3/INO80C/TFPT/MBD5/MCRS1/PSMB5/PSMD6/OTUD4/USP4/PSMC3/TOR1A/ACTR5/SHMT2/IFIH1/TAB1/PSME3/USP16/USP31/TRIM21/TNIP1/PSMC6/USP26/OTUD5/YY1/DESI2/BIRC3/TNIP3/SENP8/ASXL2/USP1/ADRB2/CDC25A/USPL1/HGS/STAMBPL1/UBC/FOXK2/USP30/FOXO4/USP27X/TOMM20/USP11/ATXN3/COPS2/BRCA1/USP10/YOD1/TRAF2/USP7/USP35/KAT2A/MDM2/CCNA1/DDB2/STAMBP/PSMC1/TAF9B/CLSPN/USP49/PSMD8/UBXN1/PSMA2/OTUD3/OGT/BAP1/CDC20/CCNA2/INO80D/PSMC5/PSMC2/POLB/PSMB2/PSMD4/VCP/COPS8/GPS1/RHOA/USP22/BRCC3/USP19/PSMD1/TADA3/USP37/ACTL6A/ATXN3L/JOSD2/PSMB4/COPS3/USP32/PSMD9/PSMD3/SIAH2	149
BP	GO:0002720	positive regulation of cytokine production involved in immune response	36/7096	54/18670	1.821e-05	0.0005848	0.0004359	NOD2/BCL10/DDX21/WNT5A/TNFRSF14/NLRP3/MIF/CD74/GPRC5B/LILRB1/TICAM1/CD226/IL18R1/FFAR2/CD36/HLA-F/TRAF6/TLR4/DDX58/HLA-E/RSAD2/IL1B/IL1R1/HLA-G/MAVS/IL6/DDX1/FZD5/KIR2DL4/IL18/TRAF2/TNFSF4/NR4A3/TRIM6/PRKCZ/MALT1	36
BP	GO:0032612	interleukin-1 production	66/7096	115/18670	1.849e-05	0.0005882	0.0004385	IGF1/NOD2/CX3CR1/ACP5/ANXA1/IL1R2/CLEC7A/WNT5A/AZU1/ARG2/S1PR3/MNDA/LILRA5/NLRP3/TNFAIP3/LILRA2/NLRP12/JAK2/GSTP1/P2RX7/EGR1/GBP5/AIM2/TRIM16/HSPB1/CD36/PANX1/SERPINB1/TLR4/CASP8/ABCA1/IL1B/AGER/PML/HMGB1/TYROBP/S100A13/SPHK1/HDAC2/MEFV/CASP1/LGALS9/FZD5/CPTP/F2R/CMA1/TLR8/APOA1/TREM2/NLRP1/HAVCR2/IFNG/SUCNR1/NLRP2/CD33/FOXP1/APP/CX3CL1/CCL19/MALT1/CCR7/HMGB4/NR1H4/TLR6/GHRL/IGHD	66
BP	GO:0001666	response to hypoxia	175/7096	359/18670	1.85e-05	0.0005882	0.0004385	SLC8A1/EPAS1/CBFA2T3/KCNMB1/TLR2/LDHA/NR4A2/PINK1/RBPJ/PGK1/LMNA/TMBIM6/CAPN2/VEGFB/PTGS2/PSMB9/PDLIM1/PPARD/GNB1/PMAIP1/PSMB8/SIRT4/BIRC2/ACTN4/AHCY/MYC/RGCC/EGR1/PSMA5/ADAM8/PSMD11/HMOX1/SLC9A1/PSME1/CXCL12/DPP4/SUV39H2/PKM/SLC2A8/HIGD1A/TGFB1/ITPR1/ALAD/FIS1/HIF1A/PAK1/PSMB10/PTK2B/LEP/PSMA1/PSMA4/ADAM15/SRF/LOXL2/RYR1/ASCL2/BMP2/VEGFA/EGLN1/CAT/CASP3/ENO1/PSMB1/UCP2/PSMC4/AGTRAP/S100B/AGER/PML/PSMD13/CREB1/RAF1/PSMB3/SIRT1/BMP7/NDRG1/HIF1AN/PLOD1/EGLN3/PPARGC1A/CITED2/PSEN2/PSMB5/PSMD6/ETS1/ARNT2/ATM/MIR34A/PSMC3/PAM/PLK3/COX4I2/SUV39H1/PSME3/BCL2/XRCC1/SCAP/PSMC6/ATP1B1/CDKN1B/CPEB1/PLOD2/ITGA2/PDK1/UBC/CYBA/CYBB/KCNK2/DDIT4/MMP14/ADA/ARNT/STUB1/DNM1L/CHRNA4/NFE2L2/PPARA/ADAM17/DNMT3A/HSP90B1/AQP3/MALAT1/ACAA2/PRKAA1/MDM2/CHRNB2/PSMC1/ERCC2/CUL2/BAD/TGFB3/CHCHD2/PSMD8/RORA/TBL2/PSMA2/ATP7A/BACH1/CLCA1/HYOU1/PIN1/OPRD1/CD34/SCFD1/CCNA2/PSMC5/MMP2/TERT/PSMC2/PSMB2/PSMD4/ND4/MTOR/KCNMA1/RHOA/RBX1/P2RX2/TM9SF4/USP19/PSMD1/SLC8A3/ROCK2/ENDOG/PSMB4/ALDH3A1/UCN3/CD24/MGARP/PSMD9/PSMD3/CPEB2/FOXO3/PLEKHN1/MIR146A/FUNDC1	175
BP	GO:0051648	vesicle localization	152/7096	306/18670	1.862e-05	0.0005891	0.0004392	SERPINA1/F5/APBA1/PINK1/STX11/DNM3/RAP1B/SYT11/MCFD2/BLOC1S2/BBS5/RAB11A/KLHL12/MLPH/ACTN4/CTSC/SEC22B/P2RX7/CTBP2/CD59/GSK3B/ANKRD28/KIF3B/STXBP1/UNC13B/KIFAP3/GRIPAP1/SAR1B/TRAPPC6A/MYO5A/SYNJ1/CSNK1D/PPP6R1/FAM91A1/WDR11/IKBKG/CNIH3/ITGA4/FBXL20/AP3M2/TRAPPC5/CDK5/TRAK2/PAFAH1B1/ASIP/CTSZ/RAB3GAP1/ARFGAP3/TMEM230/TMED10/DTNBP1/CLN3/VPS33A/RASGRP1/RAP1A/C17orf75/STARD3NL/BLOC1S6/WIPI1/BET1/BBS2/DOC2B/MKKS/MAP4K2/PREPL/GOSR2/AP1M2/LRRK2/GOSR1/MYO1C/STX5/ADCY1/SAR1A/BBS4/ARF1/PPP6C/TOR1A/DNM1/P2RX1/TRAPPC6B/ADORA2B/VPS18/TRAPPC9/NAPA/DNM2/TBC1D20/BLOC1S3/COL7A1/DCTN2/RAB5A/KIAA1107/NDEL1/BBS7/GPR143/KIF13A/LMAN1/PEF1/CAMK2A/CHRM2/YKT6/DNM1L/BLOC1S1/CHRNA4/BLOC1S4/CLASP2/SEC23IP/TRAPPC2L/AP3B1/ATP2A2/DVL1/PSEN1/CEP19/FMR1/TRAPPC3/RAB3A/CHRNB2/P2RY4/PPFIA3/TPGS1/SYT9/EXOC4/KIF1B/AP3M1/SYT1/KIF5B/TRAK1/SCFD1/PIK3CG/SYT2/VAMP1/DOC2A/SNAP29/SYT4/PRKCZ/CADPS2/SYT5/MREG/KIF1C/CDH3/BRSK1/SNCA/RIMS2/WNT7A/PICALM/NLGN2/PREB/SEC24A/SYN3/RAB27A/P2RY1/SEC16B/TRIM46	152
BP	GO:0061900	glial cell activation	38/7096	58/18670	1.967e-05	0.0006193	0.0004617	ITGAM/FPR2/TLR2/NAMPT/GRN/AZU1/CTSC/JAK2/PTPRC/TNF/MIR142/IL1B/AIF1/AGER/LDLR/LRP1/CLU/TYROBP/TTBK1/IL6/LRRK2/BACE2/CST7/ATM/SPHK1/CNTF/IFNGR1/EGFR/PSEN1/TLR8/TREM2/IFNG/TLR3/APP/SNCA/CX3CL1/SMO/TLR6	38
BP	GO:0002718	regulation of cytokine production involved in immune response	51/7096	84/18670	1.995e-05	0.0006251	0.000466	NOD2/CCR2/BCL10/DDX21/WNT5A/TNFRSF14/BCL6/NLRP3/SMAD7/MIF/HFE/TNF/IRAK3/CD74/HMOX1/GPRC5B/LILRB1/TICAM1/CD226/TGFB1/IL18R1/FFAR2/CD36/HLA-F/TRAF6/CLC/TLR4/DDX58/HLA-E/RSAD2/IL1B/TRPM4/IL1R1/HLA-G/MAVS/IL6/CD96/DDX1/FZD5/KIR2DL4/IL18/TRAF2/TNFSF4/APOA1/TGFB3/NR4A3/TLR3/TRIM6/PRKCZ/TBX21/MALT1	51
BP	GO:0002687	positive regulation of leukocyte migration	72/7096	128/18670	2.033e-05	0.0006338	0.0004725	FPR2/CCR2/RAC2/OXSR1/WNT5A/VEGFB/TNFRSF14/CAMK1D/KITLG/LGMN/PLA2G7/ADAM8/TNF/CD74/CXCL10/CXCL12/DOCK8/TGFB1/PTAFR/PTK2B/SWAP70/CXCL13/ITGA4/CD99/VEGFA/CMKLR1/AIF1/AGER/CCL5/P2RY12/HMGB1/CCL7/TNFRSF18/IL1R1/RAC1/IL6/C3AR1/MOSPD2/GPSM3/CD99L2/ZNF580/TMEM102/CCL8/SERPINE1/CCR6/MADCAM1/ITGA2/CREB3/LGALS9/MMP14/CALR/C1QBP/CXCR2/FADD/ADAM17/CCL20/TREM2/TNFSF18/BDKRB1/LBP/RHOA/TRPV4/APP/DAPK2/CCL19/TIRAP/CCL4/CCR7/CCL24/IL23A/PDGFD/S100A14	72
BP	GO:0009199	ribonucleoside triphosphate metabolic process	167/7096	341/18670	2.054e-05	0.0006353	0.0004737	IGF1/CBFA2T3/HK3/LDHA/PINK1/FBP1/PGK1/VPS9D1/STAT3/PFKFB3/NUP62/NUP160/PFKM/UQCRC2/GNAI3/PFKP/GAPDH/SLC25A25/NUP214/SLC2A6/P2RX7/UQCR11/NDUFA8/NUPR1/RAN/AK3/PGAM1/AK2/PKM/GALK1/NFS1/EIF6/TPI1/ZBTB7A/NDUFC1/TGFB1/RAB23/NUP85/CLPX/HIF1A/ISCU/SEH1L/NDUFB11/INSR/ALDOC/MBIP/NDUFS3/GUK1/NUP43/IMPDH1/NDUFA3/CTPS2/NMNAT1/ATP6V1A/ENO1/DNAJC30/ALDOA/UQCC2/NDUFA11/PARG/POM121/OGDH/CHCHD10/MOCS2/UQCR10/COX7C/GPI/ATP6V1B2/LRRK2/PFKFB4/PPARGC1A/FLCN/COX7A2L/DHTKD1/NME3/NDUFA4/SLC25A12/SHMT2/LDHC/NME4/PRKAG2/MYOG/NCOR1/COX4I2/NDUFA1/GTPBP1/PFKFB1/NUP88/HDAC4/ATP1B1/RHOQ/NME1/NUDT5/TEFM/COQ9/NUP107/COA6/COX15/NDUFA10/FOXK2/NDUFB1/DDIT4/NDUFB5/UQCRQ/PGK2/PFKFB2/MOCS3/ARNT/DNM1L/NDUFS1/UCK1/SLC25A33/PPARA/NUP93/SLC25A13/NDUFB8/PRKAA1/PSEN1/DNAJC15/NUP205/ENO2/PID1/SURF1/NDUFB6/BAD/SLC4A1/TREM2/CTPS1/CAD/NUP50/IFNG/PRKAG1/OGT/ATP7A/NDUFB3/SDHA/ESRRB/ZBTB20/VCP/NDUFS7/ADPGK/NDUFV2/ND4/SDHD/RHOA/UCKL1/TAZ/APP/SNCA/UQCRB/ATP6V1B1/AMPD3/ABCD1/NDUFB2/SDHAF2/GIMAP7/MYH3/COX6C/ATP1A2/PFKL/CTNS/NDUFS2/POM121C/AAAS/FIGNL1/NDUFA7/COX7B	167
BP	GO:0048511	rhythmic process	147/7096	295/18670	2.06e-05	0.0006353	0.0004737	HEBP1/ARNTL2/HS3ST2/NAMPT/CIPC/NFIL3/ATG7/RETN/EGR3/SRD5A1/JUND/BHLHE40/NAGLU/KLF10/PLEKHA1/DBP/FBXW7/AHCY/SIK1/LGR4/PER2/ATF5/EGR1/MAGED1/EZH2/HNRNPR/GSK3B/KAT2B/THRAP3/SUV39H2/ATF4/AXL/UBE3A/CDK4/SIN3A/ARRB1/GNAQ/SGPL1/ZNF830/LEP/CSNK1D/METTL3/ENOX2/NFKB2/PTX3/RBM4/DDB1/RBM4B/HSPA5/TEF/USP9X/CDK5/CASP3/PSPC1/RELB/KDM2A/SRRD/NR1D2/DHX9/AHR/PML/TNFRSF11A/CREB1/SIRT1/SFPQ/KLF9/EGR2/PPARGC1A/MYCBP2/TIMP4/FBXL3/CRTC1/ADCY1/PROK1/ETS1/CREM/CSNK1E/SETX/HDAC2/PAM/NCOR1/SUV39H1/MYBBP1A/MAPK8/PCNA/KDM8/SERPINE1/CBX3/ID2/CASP2/NR1H3/OPN3/INHBA/CPT1A/TYMS/KDM5B/TIMELESS/HNRNPD/PRMT5/PROK2/ADA/KCNA2/DNM1L/DTL/PPP1CC/PPP1CA/EGFR/TPH2/PPARA/CLOCK/USP7/FZD4/SLIT2/GFPT1/PRKAA1/CHRNB2/TGFB3/HNF1B/RORA/ARNTL/OGT/KDM5C/PPP1CB/HLF/FSHR/PER3/OPRL1/MTOR/TYRO3/GHRH/TOP1/ROCK2/NRIP1/BMPR1B/TARDBP/MMP19/NR2F6/GNA11/SIAH2/TOP2A/OPN4/FOXO3/GHRL/NTRK2/KISS1/MAPK9/SLIT3	147
BP	GO:0006521	regulation of cellular amino acid metabolic process	40/7096	62/18670	2.067e-05	0.0006353	0.0004737	NQO1/ATP2B4/OAZ2/PSMB9/PSMB8/SIRT4/PSMA5/PSMD11/SLC7A11/PSME1/SLC7A7/PSMB10/PSMA1/PSMA4/OAZ3/PSMB1/ODC1/PSMC4/PSMD13/PSMB3/PSMB5/PSMD6/PSMC3/PSME3/PSMC6/BHMT/AZIN1/PSMC1/PSMD8/PSMA2/PSMC5/PSMC2/PSMB2/PSMD4/ATCAY/PSMD1/PSMB4/NR1H4/PSMD9/PSMD3	40
BP	GO:0051090	regulation of DNA-binding transcription factor activity	206/7096	432/18670	2.115e-05	0.000647	0.0004823	KLF4/MYD88/S100A9/S100A8/FOS/NOD2/S100A12/TRIM32/CX3CR1/TLR2/BCL10/PINK1/MAD2L2/WNT5A/STAT3/PIM1/HCK/BHLHE40/RNF41/NLRP3/CHP1/FLNA/SMAD7/TNFAIP3/CAMK1D/NLRC5/CD40/KEAP1/DDRGK1/CEBPG/CIB1/SIK1/FLOT1/G3BP2/NLRP12/RGCC/JAK2/ALK/UBE2N/ADAM8/DVL2/TNF/EZH2/IRAK3/NFKBIA/HMOX1/NUPR1/NFKB1/TRIM13/IL1RAP/PKD2/KRAS/AIM2/TICAM1/ANXA3/RELA/HCLS1/TRIM37/LRP8/ZBTB7A/IRAK4/TGFB1/IL18R1/CYP1B1/LPAR5/ARRB1/WFS1/TRIM22/CD36/LRRFIP1/SRF/TAB3/TRAF6/NFKB2/TRIM26/IKBKG/TLR4/DDX58/TRAF3/VEGFA/EGLN1/CARD14/CAT/CACTIN/NPM1/SP100/CMKLR1/NFKBID/IL1B/AGER/CYTL1/DHX9/ARHGEF2/TAF12/SFRP4/BUD31/TNFRSF11A/CRTC2/TRADD/CLU/RBCK1/SIRT1/SAV1/BMP7/MAVS/IL6/CYLD/PPARGC1A/ZNF431/FLOT2/SUMO1/CRTC1/ADCY1/SRI/EDA/CRTC3/MED13/SPHK1/HDAC2/MAPK8/TAB1/TRIM21/TRAPPC9/PRKD2/SETD6/HDAC4/ID2/CTH/ROR1/BEX1/UBC/LGALS9/JMY/NFKBIE/FER/RAB7B/TRAF1/CAMK2A/FZD1/COMMD1/EIF2AK2/PEX14/WWP2/IL18/MID2/TRAF2/CLOCK/USP7/FZD4/TNFSF4/NFAM1/WNT1/TAX1BP1/MAPK1/SIGIRR/TCF7L2/DAP/TNFRSF4/TRAF5/CAPN3/MAP3K13/HAVCR2/FOSL1/MAPK11/TNFSF18/FANCD2/TRIM15/PKHD1/OPRD1/MXI1/RB1/TLR3/MAP2K5/PPP2R5B/MEN1/NLRP2/CARM1/MTDH/EIF2AK4/PRKCZ/RELN/PRKCQ/HDAC5/MBTPS2/IL18RAP/APP/FANCA/CX3CL1/FZD2/ADORA3/RLIM/MALT1/TIRAP/CHUK/SFRP5/PAXIP1/WNT10B/SMO/TONSL/NR1H4/NLRC3/TLR6/PTCH1/MAPK9/FOXH1/BRMS1	206
BP	GO:0031343	positive regulation of cell killing	43/7096	68/18670	2.139e-05	0.0006488	0.0004837	ITGAM/CLEC7A/STX7/GAPDH/CD1C/PTPRC/P2RX7/CD1E/LAMP1/CD226/FAM49B/HLA-F/HLA-E/HLA-B/RASGRP1/CD1B/TYROBP/HLA-G/CD5L/HLA-C/BCL2L11/FCER2/PVR/LAG3/CD1D/IL12RB1/CD1A/PGLYRP4/ULBP2/CRTAM/VAV1/FADD/PRF1/AP1G1/BAD/HLA-A/IFNG/NCR3/IL12B/SH2D1A/MICA/IL18RAP/IL23A	43
BP	GO:0050873	brown fat cell differentiation	29/7096	41/18670	2.141e-05	0.0006488	0.0004837	SH2B2/METRNL/PEX11A/FABP4/ARL4A/FNDC5/PTGS2/DUSP10/PLAC8/RGS2/CEBPB/ZNF516/ALDH6A1/LEP/NAPEPLD/ZBTB7B/LAMB3/CEBPA/ADRB1/SIRT1/PPARGC1A/FTO/LRG1/ADRB2/UCP1/NUDT7/MTOR/TRPV4/VSTM2A	29
BP	GO:1901293	nucleoside phosphate biosynthetic process	188/7096	390/18670	2.155e-05	0.0006499	0.0004845	IGF1/PNP/CBFA2T3/HK3/CDS1/NAMPT/QPRT/PDK4/UPP1/LDHA/PINK1/FBP1/PARP9/PGK1/CBR4/VPS9D1/STAT3/PFKFB3/NUP62/NUP160/GPAM/PFKM/PTGS2/PFKP/GAPDH/PANK2/NUP214/ACOT7/NMNAT3/CDS2/PAPSS1/ACSL5/SLC2A6/ME1/P2RX7/ELOVL5/NUPR1/AK3/PGAM1/AK2/PKM/PDK2/GALK1/EIF6/TPI1/ZBTB7A/TGFB1/GMPS/DGUOK/NUP85/HIF1A/SCD/SEH1L/PANK3/ADK/INSR/ALDOC/CDADC1/PRPSAP1/PANK1/GUK1/PAICS/NUP43/IMPDH1/ACSL4/CTPS2/ACLY/NMNAT1/AGPAT3/ENO1/IDO1/DNAJC30/ALDOA/GSTZ1/AK8/PARP16/NADK2/CMPK1/TECR/TK1/POM121/MPC2/ACACB/RFK/OGDH/CMPK2/ELOVL7/GPI/ADCY7/PFKFB4/PPARGC1A/AGPAT4/FLCN/MLYCD/IDH2/KYNU/HAAO/ADCY1/DHTKD1/NME3/ACSL6/SLC25A12/LDHC/NME4/PRKAG2/MYOG/NCOR1/ADORA2B/PFKFB1/ATIC/ADCY3/NUP88/HDAC4/PAPSS2/NME1/NUP107/PDK1/PRPS1/NMRK2/PPAT/TYMS/PDHB/FOXK2/RRM2/NMNAT2/DDIT4/FLAD1/AMPD2/PGK2/PFKFB2/ADA/DCK/ARNT/DLAT/SHMT1/PDP2/UCK1/PPARA/NUP93/TBPL1/SLC25A13/TK2/RRM2B/AGPAT5/IDO2/SLC5A8/PRKAA1/PSEN1/PDHA2/NUP205/AK6/MAPK1/ENO2/PID1/DCTD/GUCY2D/SLC4A1/PRPS1L1/TREM2/CTPS1/CAD/NUP50/IFNG/PRKAG1/OGT/PDP1/PRPS2/ESRRB/ZBTB20/VCP/ADPGK/AGPAT1/UCKL1/TAZ/APP/SNCA/ELOVL6/UPP2/AMPD3/LHPP/PDPR/DUT/AGPAT2/PFKL/PNKP/POM121C/AAAS/HSD17B12	188
BP	GO:0051169	nuclear transport	169/7096	346/18670	2.218e-05	0.0006657	0.0004963	CDKN1A/APPL2/TXNIP/LMNA/TSC1/NXF1/SRSF5/STAT3/BARD1/NUP62/NUP160/IPO13/PTGS2/CHP1/STRADB/RITA1/FLNA/DDX20/CHTOP/NUP214/ENY2/AGFG1/KHDRBS1/NFKBIA/AKAP13/TNPO1/RAN/GSK3B/ALYREF/RNPS1/HCLS1/EIF6/MX2/MAGOHB/TGFB1/SARNP/RAB23/NUP85/NXT1/CBLB/CD36/SEH1L/LEP/PRKCD/PTTG1IP/HYAL2/YTHDC1/RBM4/KPNA4/NUP43/IFI27/HNRNPA1/CDK5/SFN/NPM1/SP100/HNRNPA2B1/EMD/ZPR1/IL1B/RBM8A/HTATIP2/SNUPN/SNRPB/HMGA1/FYTTD1/GEMIN6/DDX19B/UBR5/DHX9/U2AF1/MMP12/MDFIC/POM121/ZNF593/PML/SRSF3/GEMIN7/SYMPK/XPOT/MAVS/EGR2/CCHCR1/CPSF3/LRRK2/NOLC1/SNRPD1/IPO4/BANF1/RBM27/RSRC1/FIP1L1/BMP4/NEDD4/LSG1/NUP88/RGS14/ANP32C/THOC2/SRSF6/SNRPF/SRSF7/PRKACA/CSE1L/NUP107/CDC40/THOC5/POLR2D/CALR/NXT2/NUP62CL/PPP1CC/AHCYL1/U2AF1L4/TXN/EIF5A/NUP93/IPO9/LTV1/THOC6/RIOK2/SSB/SRRM1/PSEN1/NUP205/MDM2/IPO7/MAPK1/TCF7L2/YWHAE/PHAX/KPNA1/ANKLE1/SRSF4/EIF4E/NUP50/IFNG/ARNTL/ATXN1/PRKAG1/ANP32D/CHP2/DHX38/TNPO3/MCM3AP/PCID2/CPSF2/RANBP6/NPAP1/PKIA/SPRN/CPSF1/MALT1/MBTPS1/KPNB1/STRADA/APPL1/XPO4/SMO/EIF4ENIF1/RRS1/TARDBP/POM121C/AAAS/SNRPG/CTDSPL2/NEMF/SNRPD2/UPF1	169
BP	GO:0002685	regulation of leukocyte migration	103/7096	196/18670	2.257e-05	0.0006742	0.0005027	FPR2/CCR2/CX3CR1/PTGER4/RAC2/IL27RA/DUSP1/ANXA1/BST1/LYN/OXSR1/WNT5A/VEGFB/TNFRSF14/CAMK1D/KITLG/MIF/LGMN/PLA2G7/ADAM8/TNF/CD74/HMOX1/CXCL10/CXCL12/MPP1/DOCK8/TGFB1/PTAFR/PTK2B/SWAP70/CXCL13/ITGA4/CD99/ABR/VEGFA/CMKLR1/AIF1/AGER/CCL5/P2RY12/HMGB1/CRK/CCL7/TNFRSF18/IL1R1/RAC1/IL6/CD200R1/BCR/C3AR1/MOSPD2/BMP5/GPSM3/CD99L2/ZNF580/TMEM102/CCL8/SERPINE1/CCR6/MADCAM1/ITGA2/GPR18/CREB3/CD300A/LGALS9/GCSAM/RABGEF1/MMP14/ADA/CALR/PLCB1/MST1/C1QBP/CXCR2/FADD/ADAM17/CCL20/JAM3/SLIT2/MSN/TREM2/TNFSF18/BDKRB1/C10orf99/LBP/RHOA/TRPV4/C5AR2/APP/DAPK2/CXCR3/CCL19/TIRAP/CCL4/CCR7/GREM1/CCL24/HOXA7/SLAMF8/IL23A/PDGFD/S100A14	103
BP	GO:1903708	positive regulation of hemopoiesis	98/7096	185/18670	2.311e-05	0.0006873	0.0005124	FOS/PNP/NFKBIZ/LILRB2/ANXA1/EGR3/ATP6AP1/STAT3/KLF10/BCL6/NLRP3/DUSP10/KITLG/STAT1/IL4R/CBFB/PTPRC/IL15/ADAM8/TNF/CD74/TESC/IL7R/HCLS1/AXL/FAM210B/TGFB1/HIF1A/SOCS5/ROR2/LILRB4/TRAF6/ZBTB1/FLT3LG/ZBTB7B/NFKBID/CASP8/AGER/RASGRP1/PIK3R6/ISG15/HMGB1/CREB1/IL7/TYROBP/TESPA1/HLA-G/TOX/ACVR1B/CYLD/TAL1/ETS1/VNN1/TMEM64/N4BP2L2/HMGB2/ID2/PPP2R3C/INHBA/IL12RB1/LGALS9/EVI2B/BTN2A2/RAB7B/MMP14/ADA/ARNT/HLX/IL18/FADD/AP3B1/SCIN/ATXN1L/TNFSF4/SART1/DCSTAMP/SOCS1/BAD/TREM2/IFNG/PCID2/CD4/RB1/IL12B/PRKCZ/CD80/RHOA/SLC9B2/CD83/CCL19/MALT1/ZBTB16/TRIM58/PRMT1/PRKCA/IL23A/FOXO3/THPO	98
BP	GO:0009165	nucleotide biosynthetic process	186/7096	386/18670	2.445e-05	0.000714	0.0005323	IGF1/PNP/CBFA2T3/HK3/CDS1/NAMPT/QPRT/PDK4/UPP1/LDHA/PINK1/FBP1/PARP9/PGK1/CBR4/VPS9D1/STAT3/PFKFB3/NUP62/NUP160/GPAM/PFKM/PTGS2/PFKP/GAPDH/PANK2/NUP214/ACOT7/NMNAT3/CDS2/PAPSS1/ACSL5/SLC2A6/ME1/P2RX7/ELOVL5/NUPR1/AK3/PGAM1/AK2/PKM/PDK2/GALK1/EIF6/TPI1/ZBTB7A/TGFB1/GMPS/DGUOK/NUP85/HIF1A/SCD/SEH1L/PANK3/ADK/INSR/ALDOC/CDADC1/PRPSAP1/PANK1/GUK1/PAICS/NUP43/IMPDH1/ACSL4/CTPS2/ACLY/NMNAT1/AGPAT3/ENO1/IDO1/DNAJC30/ALDOA/GSTZ1/AK8/PARP16/NADK2/CMPK1/TECR/POM121/MPC2/ACACB/RFK/OGDH/CMPK2/ELOVL7/GPI/ADCY7/PFKFB4/PPARGC1A/AGPAT4/FLCN/MLYCD/IDH2/KYNU/HAAO/ADCY1/DHTKD1/NME3/ACSL6/SLC25A12/LDHC/NME4/PRKAG2/MYOG/NCOR1/ADORA2B/PFKFB1/ATIC/ADCY3/NUP88/HDAC4/PAPSS2/NME1/NUP107/PDK1/PRPS1/NMRK2/PPAT/TYMS/PDHB/FOXK2/RRM2/NMNAT2/DDIT4/FLAD1/AMPD2/PGK2/PFKFB2/ADA/DCK/ARNT/DLAT/SHMT1/PDP2/UCK1/PPARA/NUP93/TBPL1/SLC25A13/TK2/RRM2B/AGPAT5/IDO2/SLC5A8/PRKAA1/PSEN1/PDHA2/NUP205/AK6/MAPK1/ENO2/PID1/DCTD/GUCY2D/SLC4A1/PRPS1L1/TREM2/CTPS1/CAD/NUP50/IFNG/PRKAG1/OGT/PDP1/PRPS2/ESRRB/ZBTB20/VCP/ADPGK/AGPAT1/UCKL1/TAZ/APP/SNCA/ELOVL6/UPP2/AMPD3/PDPR/DUT/AGPAT2/PFKL/PNKP/POM121C/AAAS/HSD17B12	186
BP	GO:0032611	interleukin-1 beta production	59/7096	101/18670	2.448e-05	0.000714	0.0005323	IGF1/NOD2/CX3CR1/ACP5/CLEC7A/WNT5A/AZU1/ARG2/S1PR3/MNDA/LILRA5/NLRP3/TNFAIP3/LILRA2/NLRP12/JAK2/GSTP1/P2RX7/EGR1/GBP5/AIM2/TRIM16/HSPB1/CD36/PANX1/SERPINB1/TLR4/CASP8/ABCA1/IL1B/AGER/PML/HMGB1/TYROBP/SPHK1/MEFV/CASP1/LGALS9/FZD5/CPTP/F2R/CMA1/TLR8/APOA1/TREM2/NLRP1/IFNG/SUCNR1/NLRP2/CD33/FOXP1/APP/CX3CL1/CCL19/MALT1/CCR7/HMGB4/TLR6/GHRL	59
BP	GO:0034440	lipid oxidation	59/7096	101/18670	2.448e-05	0.000714	0.0005323	PDK4/ALDH3A2/APPL2/HADHB/POR/PPARD/HADH/ADIPOR1/ACAA1/SIRT4/PHYH/PLA2G7/SCP2/ETFA/CPT2/AUH/ABCD3/LEP/ECH1/ACADM/ACADS/DECR1/ACOX1/ETFDH/ECI2/SLC27A2/HSD17B4/ACACB/ACOX2/DGAT2/FABP3/IRS2/BDH2/PPARGC1A/DECR2/MLYCD/PRKAG2/ECI1/ETFB/PEX13/TYSND1/CPT1A/EHHADH/ACADVL/HADHA/PPARA/ACAA2/ADIPOR2/PRKAA1/ACOX3/NR4A3/CROT/MTOR/ABCD1/HACL1/ADH7/SESN2/HAO1/ACOT8	59
BP	GO:0019058	viral life cycle	161/7096	328/18670	2.454e-05	0.000714	0.0005323	CLEC5A/TRIM32/CD55/WWP1/ITGA5/NUP62/NMT2/ITGB7/NUP160/FCN1/PLSCR1/ITGB5/TNFRSF14/NUP214/F11R/SCARB1/OASL/LAMP3/IFITM2/CTBP2/LAMP1/TNF/IFITM1/CD74/UBP1/NFIA/TRIM13/VPS37B/RAN/IFITM3/APOE/SLAMF1/DPP4/AXL/CHMP4B/PCBP1/NUP85/XPR1/MORC2/SEH1L/ISG20/STAU1/NCAM1/PTX3/HYAL2/TRIM26/DDB1/DEK/NUP43/ADARB1/OAS3/IFI27/CD209/RSAD2/FURIN/CCL5/VPS37C/LDLR/VTA1/SRPK2/CTSB/POM121/PML/ISG15/VAPB/TRIM11/RAB43/APOBEC3G/RAB29/MAVS/CR1/APOBEC3C/IFIT5/CCR5/DDX3X/ILF3/SELPLG/BANF1/ZC3HAV1/TRIM21/TARBP2/VPS18/BCL2/CCL8/TBC1D20/TNIP1/NUP88/CHMP2A/INPP5K/CCNK/TSG101/MX1/RAB5A/TOP2B/PVR/NUP107/IST1/LGALS1/SETDB1/UBAP1/ITGA2/CR2/RNASEL/UBC/PCBP2/CXCR6/PCSK5/SLC10A1/LGALS9/IFIT1/CHMP1A/SRPK1/HYAL3/VPS4B/GPR15/LAMTOR5/EIF2AK2/EGFR/CNOT7/WWP2/PKN2/NUP93/MID2/TFRC/ANXA2P2/SLC20A2/NUP205/FMR1/SIVA1/FBXL2/KPNA1/SMC3/TNFRSF4/ATG16L2/NUP50/TRIM15/CD4/HSP90AB1/TRIM6/EIF2AK4/VCP/PC/CD80/ANXA2/TYRO3/DAG1/CDHR3/ADAR/KPNB1/CHMP1B/PPIB/ROCK2/HAVCR1/NUCKS1/MOG/POM121C/AAAS/TOP2A/APCS/CLDN6/BTBD17	161
BP	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	97/7096	183/18670	2.456e-05	0.000714	0.0005323	MYD88/HTR2B/NOD2/S100A12/FYN/TRIM32/CX3CR1/BCL10/PINK1/TNIP2/DDX21/NUP62/FLNA/RHOC/CD40/DDRGK1/BIRC2/WLS/SHISA5/UBE2N/TNF/CD74/HMOX1/AKAP13/GPRC5B/TRIM13/TICAM1/REL/RELA/IRAK4/TRIM22/CD36/TAB3/TRAF6/IKBKG/TLR4/PLK2/ABL1/TNFSF10/CASP8/IL1B/S100B/MIER1/S100A4/ATP2C1/TRADD/RBCK1/IL1RN/MAVS/S100A13/IFIT5/EDA/APOL3/ZDHHC13/EDAR/TGM2/ANKRD17/CTH/BIRC3/ROR1/LGALS1/DDX1/CASP1/ALPK1/LGALS9/LPAR1/F2R/SLC20A1/TNFRSF10B/MUL1/GOLT1B/SECTM1/FADD/MID2/TRAF2/TMED4/TIFA/TRAF5/UBE2I/SLC44A2/CD4/TLR3/MTDH/RHOA/PIM2/CX3CL1/TSPAN6/CCL19/MALT1/TIRAP/CHUK/CCR7/PELI2/GJA1/TLR6/CXXC5/IL37	97
BP	GO:0019395	fatty acid oxidation	58/7096	99/18670	2.539e-05	0.0007314	0.0005453	PDK4/ALDH3A2/APPL2/HADHB/POR/PPARD/HADH/ADIPOR1/ACAA1/SIRT4/PHYH/SCP2/ETFA/CPT2/AUH/ABCD3/LEP/ECH1/ACADM/ACADS/DECR1/ACOX1/ETFDH/ECI2/SLC27A2/HSD17B4/ACACB/ACOX2/DGAT2/FABP3/IRS2/BDH2/PPARGC1A/DECR2/MLYCD/PRKAG2/ECI1/ETFB/PEX13/TYSND1/CPT1A/EHHADH/ACADVL/HADHA/PPARA/ACAA2/ADIPOR2/PRKAA1/ACOX3/NR4A3/CROT/MTOR/ABCD1/HACL1/ADH7/SESN2/HAO1/ACOT8	58
BP	GO:0072527	pyrimidine-containing compound metabolic process	58/7096	99/18670	2.539e-05	0.0007314	0.0005453	TYMP/CDS1/SLC19A2/UPP1/SLC25A19/GPAM/ACPP/CDS2/ALDH6A1/AK3/TET2/NEIL2/UNG/NT5C/CDADC1/CTPS2/AGPAT3/DPYD/CMPK1/TK1/TPK1/CMPK2/CDIPT/APOBEC3G/TDG/APOBEC3C/AGPAT4/NME3/APOBEC2/NME4/NME1/PRPS1/TYMS/DCK/SHMT1/UCK1/TBPL1/TK2/AGPAT5/APOBEC3B/MAPK1/THTPA/DCTD/CTPS1/CAD/CDA/DCTPP1/AGPAT1/MTOR/UCKL1/NT5C3A/NT5M/UPP2/DUT/AGPAT2/MBD4/TET1/SMUG1	58
BP	GO:1902107	positive regulation of leukocyte differentiation	79/7096	144/18670	2.802e-05	0.0008037	0.0005992	FOS/PNP/NFKBIZ/LILRB2/ANXA1/EGR3/ATP6AP1/KLF10/BCL6/NLRP3/DUSP10/KITLG/IL4R/CBFB/PTPRC/IL15/ADAM8/TNF/CD74/TESC/IL7R/HCLS1/AXL/TGFB1/SOCS5/ROR2/LILRB4/TRAF6/ZBTB1/FLT3LG/ZBTB7B/NFKBID/CASP8/AGER/RASGRP1/PIK3R6/HMGB1/CREB1/IL7/TYROBP/TESPA1/HLA-G/TOX/CYLD/VNN1/TMEM64/ID2/PPP2R3C/IL12RB1/LGALS9/EVI2B/BTN2A2/MMP14/ADA/HLX/IL18/FADD/AP3B1/TNFSF4/SART1/DCSTAMP/SOCS1/BAD/TREM2/IFNG/PCID2/CD4/RB1/IL12B/PRKCZ/CD80/RHOA/SLC9B2/CD83/CCL19/MALT1/ZBTB16/PRKCA/IL23A	79
BP	GO:0060333	interferon-gamma-mediated signaling pathway	54/7096	91/18670	2.899e-05	0.0008279	0.0006172	FCGR1B/GBP2/SOCS3/IRF7/PARP9/FCGR1A/IRF1/GBP1/PTPN2/HCK/NLRC5/STAT1/CD44/JAK2/OASL/TRIM68/IFNGR2/CDC37/NMI/PTAFR/TRIM22/IRF9/NR1H2/PRKCD/HLA-F/NCAM1/TRIM26/HLA-DPB1/OAS3/HLA-DPA1/HLA-E/HLA-B/SP100/PML/OAS2/HLA-G/HLA-DRA/SUMO1/HLA-C/TRIM21/NR1H3/IRF2/CAMK2A/CAMK2D/IRF8/IFNGR1/HLA-DQB2/SOCS1/HLA-A/IFNG/JAK1/TXK/HSP90AB1/CAMK2B	54
BP	GO:0002704	negative regulation of leukocyte mediated immunity	33/7096	49/18670	2.951e-05	0.0008358	0.0006231	CCR2/PTPN6/SERPINB9/BCL6/SMAD7/PTPRC/HFE/HMOX1/LILRB1/IL7R/PPP3CB/HLA-F/IL20RB/ABR/HLA-E/CLEC12B/CRK/HLA-G/CR1/BCR/CD96/PARP3/CD300A/LGALS9/RABGEF1/KIR2DL4/IL13RA2/CD84/HAVCR2/SERPINB4/MICA/TBX21/FOXF1	33
BP	GO:0051098	regulation of binding	180/7096	373/18670	2.953e-05	0.0008358	0.0006231	KLF4/IGF1/S100A10/ARF6/STMN1/MAD2L2/SKI/PPP2CA/PARP9/WNT5A/C9orf72/TMBIM6/DPH3/MEPCE/DDRGK1/CEBPG/LFNG/FBXW7/SMAD2/FLOT1/PER2/JAK2/CTBP2/HFE/ZNF304/NFKBIA/HMOX1/PCBD1/RAN/APOE/ERCC4/GSK3B/GMNN/DOT1L/TICAM1/TMC8/CCPG1/ACTB/ZBTB7A/TGFB1/SIN3A/GTPBP4/ARRB1/RAPGEF2/ENHO/CD36/SYAP1/LRPAP1/PRKCD/ADAM15/NRG1/TRAF6/RUVBL2/NSD1/ITGA4/TFAP4/HABP4/BMP2/HSPA5/CDK5/PLK2/BTAF1/SP100/ABL1/CTSZ/IFIT2/DTNBP1/GZMA/AGER/DHX9/ZNF593/CSNK2B/MAPRE1/LRP1/HMGB1/SYMPK/HEY1/CRK/EIF2S1/GPSM1/TTBK1/PDGFB/CYLD/CDK9/LRRK2/TDG/PLAUR/SUMO1/BTBD1/SRI/CSNK1A1/CSNK1E/DTX3L/HDAC2/MARK3/CYP2D6/MAPK8/NRP1/DISC1/MMP9/PLXND1/PLCL1/BCL2/BMP4/BAX/HMGB2/HDAC4/ID2/MARK2/NME1/PRKACA/ADRB2/ITGA2/DERL1/ZFP90/RSF1/PEX19/GTF2F1/PDX1/IFIT1/CLN5/HES1/ZMPSTE24/KDM4D/STUB1/MED25/PPP1CA/PEX14/TXN/PPARA/TRAF2/BAG2/HEY2/ANXA2P2/DVL1/CPNE1/PSEN1/FMR1/TCF7L2/ACD/CTHRC1/EPB41/ERCC2/EIF4G1/PLCL2/IFNG/EFHB/SPTA1/GNL3L/PIN1/HSP90AB1/RB1/MEN1/CARM1/MSX1/EDF1/TERT/TRIM6/ANXA2/HDAC5/AURKA/APP/PIM2/PAX7/ITGB1BP1/TTBK2/MET/SLN/TIRAP/BAK1/HOXA3/TRAF4/AIDA/GCG/CFHR5/SMO/NUCKS1/P2RY1/GAS8/MEF2C	180
BP	GO:0032388	positive regulation of intracellular transport	111/7096	215/18670	3.063e-05	0.0008624	0.0006429	ITGAM/FYN/EZR/RAC2/PINK1/OAZ2/PTGS2/CHP1/HPS4/FLNA/CIB1/FBXW7/IL4R/BCAP31/KHDRBS1/C2CD5/SCP2/RAN/GSK3B/EDEM1/HCLS1/CSNK2A2/TGFB1/RDX/STXBP1/MIEF1/UNC13B/FIS1/SAR1B/PAK1/PCM1/LEP/PRKCD/UBE2D3/CEP131/HYAL2/HTRA2/FGR/CDK5/SFN/HRAS/EMD/ZPR1/IL1B/UBR5/DHX9/ATG13/EHD1/SPAG5/RAB29/MAVS/EDEM2/MYO1C/RHOU/PDCD5/MLC1/SAR1A/ARF1/RBM27/ARIH2/PLK3/ABLIM3/ADORA2B/TBC1D20/NEDD4/BCAS3/MICALL2/KIF20B/PRKACA/MTMR2/UBL4B/SREBF2/FZD5/DNM1L/STX18/HSPA1L/CEMIP/ANXA2P2/RIOK2/PRKAA1/PSEN1/MDM2/MAPK1/TCF7L2/SH3GLB1/YWHAE/MSN/SYT9/UBL5/RUFY3/IFNG/BAP1/CHP2/SYT1/KIF5B/B3GAT3/TMEM30A/SNX4/CACNB3/ANXA2/CDH3/ITGB1BP1/PDCD10/TM9SF4/ICE1/XPO4/SMO/TARDBP/CTDSPL2/SEC16B/TRIM46	111
BP	GO:0006913	nucleocytoplasmic transport	167/7096	343/18670	3.083e-05	0.0008624	0.0006429	CDKN1A/APPL2/TXNIP/LMNA/TSC1/NXF1/SRSF5/STAT3/BARD1/NUP62/NUP160/IPO13/PTGS2/CHP1/STRADB/RITA1/FLNA/DDX20/CHTOP/NUP214/ENY2/AGFG1/KHDRBS1/NFKBIA/AKAP13/TNPO1/RAN/GSK3B/ALYREF/RNPS1/HCLS1/EIF6/MX2/MAGOHB/TGFB1/SARNP/RAB23/NUP85/NXT1/CBLB/CD36/SEH1L/LEP/PRKCD/PTTG1IP/HYAL2/YTHDC1/RBM4/KPNA4/NUP43/IFI27/HNRNPA1/CDK5/SFN/NPM1/SP100/HNRNPA2B1/EMD/ZPR1/IL1B/RBM8A/HTATIP2/SNUPN/SNRPB/FYTTD1/GEMIN6/DDX19B/UBR5/DHX9/U2AF1/MMP12/MDFIC/POM121/ZNF593/PML/SRSF3/GEMIN7/SYMPK/XPOT/MAVS/EGR2/CCHCR1/CPSF3/LRRK2/NOLC1/SNRPD1/IPO4/RBM27/RSRC1/FIP1L1/BMP4/NEDD4/LSG1/NUP88/RGS14/ANP32C/THOC2/SRSF6/SNRPF/SRSF7/PRKACA/CSE1L/NUP107/CDC40/THOC5/POLR2D/CALR/NXT2/NUP62CL/PPP1CC/AHCYL1/U2AF1L4/TXN/EIF5A/NUP93/IPO9/LTV1/THOC6/RIOK2/SSB/SRRM1/PSEN1/NUP205/MDM2/IPO7/MAPK1/TCF7L2/YWHAE/PHAX/KPNA1/ANKLE1/SRSF4/EIF4E/NUP50/IFNG/ARNTL/ATXN1/PRKAG1/ANP32D/CHP2/DHX38/TNPO3/MCM3AP/PCID2/CPSF2/RANBP6/NPAP1/PKIA/SPRN/CPSF1/MALT1/MBTPS1/KPNB1/STRADA/APPL1/XPO4/SMO/EIF4ENIF1/RRS1/TARDBP/POM121C/AAAS/SNRPG/CTDSPL2/NEMF/SNRPD2/UPF1	167
BP	GO:0090316	positive regulation of intracellular protein transport	83/7096	153/18670	3.087e-05	0.0008624	0.0006429	ITGAM/FYN/RAC2/PINK1/OAZ2/PTGS2/CHP1/HPS4/FLNA/CIB1/FBXW7/BCAP31/C2CD5/RAN/GSK3B/EDEM1/HCLS1/CSNK2A2/TGFB1/MIEF1/FIS1/SAR1B/PAK1/PCM1/LEP/PRKCD/UBE2D3/CEP131/HYAL2/HTRA2/CDK5/SFN/HRAS/EMD/ZPR1/IL1B/UBR5/ATG13/RAB29/MAVS/EDEM2/MYO1C/RHOU/PDCD5/SAR1A/ARIH2/PLK3/ABLIM3/BCAS3/MICALL2/KIF20B/PRKACA/UBL4B/SREBF2/FZD5/HSPA1L/CEMIP/RIOK2/PRKAA1/PSEN1/MDM2/MAPK1/TCF7L2/SH3GLB1/YWHAE/UBL5/RUFY3/IFNG/BAP1/CHP2/KIF5B/B3GAT3/TMEM30A/CACNB3/ITGB1BP1/PDCD10/TM9SF4/ICE1/XPO4/SMO/TARDBP/CTDSPL2/SEC16B	83
BP	GO:0009185	ribonucleoside diphosphate metabolic process	77/7096	140/18670	3.128e-05	0.0008701	0.0006487	IGF1/CBFA2T3/HK3/LDHA/FBP1/PGK1/STAT3/PFKFB3/NUP62/NUP160/PFKM/PFKP/GAPDH/NUP214/SLC2A6/P2RX7/NUPR1/AK3/PGAM1/AK2/PKM/GALK1/EIF6/TPI1/MPP1/ZBTB7A/NUP85/HIF1A/SEH1L/INSR/ALDOC/GUK1/NUP43/ENO1/ALDOA/POM121/OGDH/NUDT9/GPI/PFKFB4/PPARGC1A/DHTKD1/SLC25A12/PRKAG2/MYOG/NCOR1/PFKFB1/NUP88/HDAC4/NUDT5/NUP107/FOXK2/DDIT4/PGK2/PFKFB2/ARNT/PPARA/NUP93/PRKAA1/PSEN1/NUP205/ENO2/BAD/SLC4A1/NUP50/IFNG/PRKAG1/OGT/ESRRB/ZBTB20/ADPGK/APP/AMPD3/NUDT16/PFKL/POM121C/AAAS	77
BP	GO:0070228	regulation of lymphocyte apoptotic process	35/7096	53/18670	3.236e-05	0.0008963	0.0006682	TSC22D3/PIP/BCL10/LYN/WNT5A/ARG2/BCL6/SLC46A2/MIF/P2RX7/ADAM8/CD74/PRELID1/IL7R/DOCK8/HIF1A/SLC39A10/IDO1/NFKBID/CCL5/IRS2/FNIP1/BMP4/BAX/NOC2L/CD3G/CD274/LGALS9/BIRC7/ADA/FADD/PTCRA/PRKCQ/FOXP1/PDCD1	35
BP	GO:0042098	T cell proliferation	97/7096	184/18670	3.268e-05	0.0009015	0.000672	IGF1/PNP/CCR2/FYN/RAC2/PTPN6/LILRB2/ANXA1/ELF4/CD55/SLC11A1/IRF1/ARG2/GPNMB/CCND3/TNFRSF14/SH3RF1/CEBPB/PTPRC/IL15/P2RX7/TNFRSF21/LILRB1/DOCK8/TGFB1/PPP3CB/CCDC88B/PSMB10/LEP/TNFSF13B/CORO1A/TRAF6/CLC/IL20RB/ZBTB7B/HLA-DPB1/HLA-DPA1/HLA-E/NCK1/CD209/CASP3/ABL1/IDO1/IL1B/CD151/AIF1/AGER/CCL5/RASAL3/HLA-DMB/ICOSLG/HMGB1/EFNB1/IGFBP2/IL6ST/HLA-G/IL6/CTLA4/GLMN/VSIG4/SCGB1A1/PDCD1LG2/BMP4/BAX/CD1D/IL12RB1/CD274/LGALS9/EBI3/BTN2A2/HES1/IL18/FADD/CD276/TFRC/TNFSF4/BTN3A1/MSN/TNFRSF4/HAVCR2/CTPS1/SPTA1/TNFSF18/CD4/PIK3CG/TNFRSF13C/IL12B/CD80/PRKCQ/CCL19/MALT1/TNFSF8/CD3E/GJA1/TWSG1/CD24/IL23A	97
BP	GO:0009135	purine nucleoside diphosphate metabolic process	76/7096	138/18670	3.303e-05	0.0009034	0.0006735	IGF1/CBFA2T3/HK3/LDHA/FBP1/PGK1/STAT3/PFKFB3/NUP62/NUP160/PFKM/PFKP/GAPDH/NUP214/SLC2A6/P2RX7/NUPR1/AK3/PGAM1/AK2/PKM/GALK1/EIF6/TPI1/MPP1/ZBTB7A/NUP85/HIF1A/SEH1L/INSR/ALDOC/GUK1/NUP43/ENO1/ALDOA/POM121/OGDH/NUDT9/GPI/PFKFB4/PPARGC1A/DHTKD1/SLC25A12/PRKAG2/MYOG/NCOR1/PFKFB1/NUP88/HDAC4/NUP107/FOXK2/DDIT4/PGK2/PFKFB2/ARNT/PPARA/NUP93/PRKAA1/PSEN1/NUP205/ENO2/BAD/SLC4A1/NUP50/IFNG/PRKAG1/OGT/ESRRB/ZBTB20/ADPGK/APP/AMPD3/NUDT16/PFKL/POM121C/AAAS	76
BP	GO:0009179	purine ribonucleoside diphosphate metabolic process	76/7096	138/18670	3.303e-05	0.0009034	0.0006735	IGF1/CBFA2T3/HK3/LDHA/FBP1/PGK1/STAT3/PFKFB3/NUP62/NUP160/PFKM/PFKP/GAPDH/NUP214/SLC2A6/P2RX7/NUPR1/AK3/PGAM1/AK2/PKM/GALK1/EIF6/TPI1/MPP1/ZBTB7A/NUP85/HIF1A/SEH1L/INSR/ALDOC/GUK1/NUP43/ENO1/ALDOA/POM121/OGDH/NUDT9/GPI/PFKFB4/PPARGC1A/DHTKD1/SLC25A12/PRKAG2/MYOG/NCOR1/PFKFB1/NUP88/HDAC4/NUP107/FOXK2/DDIT4/PGK2/PFKFB2/ARNT/PPARA/NUP93/PRKAA1/PSEN1/NUP205/ENO2/BAD/SLC4A1/NUP50/IFNG/PRKAG1/OGT/ESRRB/ZBTB20/ADPGK/APP/AMPD3/NUDT16/PFKL/POM121C/AAAS	76
BP	GO:0019883	antigen processing and presentation of endogenous antigen	18/7096	22/18670	3.345e-05	0.0009077	0.0006767	CD1C/TAP2/TAP1/CD1E/HFE/CD74/HLA-F/HLA-E/HLA-B/CD1B/HLA-G/TAPBP/HLA-C/CD1D/CD1A/ERAP1/HLA-A/ERAP2	18
BP	GO:1901990	regulation of mitotic cell cycle phase transition	210/7096	444/18670	3.347e-05	0.0009077	0.0006767	KLF4/TPRA1/PTPN6/DUSP1/ANXA1/PRKAR2B/TUBA1A/CDKN2D/CDKN1A/NINL/MAD2L2/GPNMB/CCND3/PSMB9/CUL1/RAB11A/MEPCE/PSMB8/DYNC1LI1/ZNF655/RNASEH2B/RGCC/HUS1B/ODF2/PSMA5/SLFN11/PSMD11/EZH2/LSM11/SPDL1/PKD2/GIGYF2/HAUS8/PSME1/BTG2/CCND2/TMOD3/GPR132/CNTRL/CDK4/TGFB1/TAOK3/RDX/SIN3A/CEP164/ZNF830/PSMB10/PCM1/MTA3/PSMA1/PSMA4/CSNK1D/CEP131/CENPE/DDB1/TFAP4/DBF4B/SYF2/CDKN2B/PLK2/SFN/KLHL22/SFI1/PAFAH1B1/RAD51B/CDK5RAP2/PSMB1/PSMC4/AIF1/NSMCE2/CDKN1C/DONSON/PML/UBE2E1/CEP76/PSMD13/MAPRE1/CDK2AP2/PSMB3/CCND1/CDC23/ESPL1/ZNF207/LCMT1/DDX3X/PSMB5/PSMD6/ATM/TNKS1BP1/CSNK1E/ANAPC5/BUB3/MUC1/HAUS2/PSMC3/KMT2E/CTDSPL/PLK3/PSME3/NACC2/UBE2E2/CCNE1/RAD17/NDC80/BCL2/PCNA/BAX/PSMC6/ANKRD17/ANAPC7/CRADD/ID2/CASP2/CTDSP1/RFWD3/CDKN1B/CDKN2C/MAD2L1BP/PRKACA/CKAP5/DCTN2/CNOT4/FHL1/CDC25A/CEP152/TUBA4A/PLAGL1/GEN1/ARID3A/ZW10/VPS4B/FOXO4/TICRR/UBE2C/BTN2A2/MIIP/DTL/CEP63/E2F4/CDC26/PLCB1/BRCA1/EGFR/CNOT7/GML/CEP57/ADAM17/RCC2/CETN2/CTDSP2/HAUS5/TUBB4A/HAUS1/RIOK2/MDM2/DLGAP5/YWHAE/PSMC1/ERCC2/ZFP36L2/EIF4G1/CLSPN/WEE1/ANAPC4/RBL2/MTBP/DCUN1D3/PSMD8/PSMA2/FBXL7/TOPBP1/CDC27/FGFR1OP/CDC20/CUL4B/PCID2/TMEM14B/RB1/CNOT10/CARM1/YWHAG/JADE1/PSMC5/PKIA/TERT/PSMC2/PSMB2/PSMD4/TRIAP1/AURKA/ANAPC11/BRSK1/APP/CDC73/RBX1/SOX4/CEP78/CCNB3/IK/PSMD1/PRMT1/ATAD5/WNT10B/PSMB4/ZFYVE19/PSMD9/KIF14/PSMD3/E2F8/ALMS1	210
BP	GO:0046578	regulation of Ras protein signal transduction	121/7096	238/18670	3.437e-05	0.0009282	0.000692	IGF1/SH2B2/RTN4R/ARF6/STMN1/LYN/FBP1/NOTCH2/CDC42SE1/ARHGEF18/RASGEF1A/NUP62/PLEKHG2/SPATA13/CYTH4/MYO9B/TIMP2/BCL6/ARHGEF3/KITLG/FLOT1/DENND1A/ALS2/SQSTM1/P2RY8/JAK2/CYTH1/FGD6/FGD5/SHOC2/EPHB2/AKAP13/ARHGDIA/KRAS/APOE/ARHGEF10L/ARHGEF40/RDX/ARRB1/KCTD10/HEG1/NRG1/ARFGEF1/STMN3/CDC42SE2/ITSN1/EPOR/ABR/NET1/ARHGDIB/RASA2/HRAS/ABL1/ARHGEF6/OPHN1/ABCA1/IQSEC1/RASGRP1/ARHGEF2/RASAL3/SHC1/CRK/RAF1/FBXO8/RAC1/MAPRE2/LPAR6/KALRN/IRS2/FLCN/STK19/BCR/RASA3/SCAI/NRP1/DNM2/KANK1/GPR18/SYNGAP1/GRB2/OBSCN/RABGEF1/ITGA3/LPAR1/SPRY1/F2R/RASGRF1/VAV1/ABL2/IQSEC2/PREX1/ITSN2/SPRY2/RALGPS1/GPR35/APOA1/STAMBP/RASAL1/ARHGEF37/IQSEC3/FGD3/OGT/MAPKAP1/ARHGEF17/SYNPO2L/FGD4/PSD4/DENND4B/EPS8L2/MAP4K4/P2RY10/MET/ARHGEF4/GPR20/MCF2L/ARFGAP1/MMD2/KIF14/ARHGEF9/PSD3/RASGRP4	121
BP	GO:0046939	nucleotide phosphorylation	75/7096	136/18670	3.488e-05	0.0009347	0.0006968	IGF1/CBFA2T3/HK3/LDHA/FBP1/PGK1/STAT3/PFKFB3/NUP62/NUP160/PFKM/PFKP/GAPDH/NUP214/SLC2A6/P2RX7/NUPR1/PGAM1/PKM/GALK1/EIF6/TPI1/ZBTB7A/NUP85/HIF1A/SEH1L/INSR/ALDOC/GUK1/NUP43/ENO1/ALDOA/AK8/CMPK1/POM121/OGDH/CMPK2/GPI/PFKFB4/PPARGC1A/DHTKD1/NME3/NME4/PRKAG2/MYOG/NCOR1/PFKFB1/NUP88/HDAC4/NME1/NUP107/FOXK2/DDIT4/PGK2/PFKFB2/ARNT/PPARA/NUP93/PRKAA1/PSEN1/NUP205/ENO2/SLC4A1/NUP50/IFNG/PRKAG1/OGT/ESRRB/ZBTB20/ADPGK/APP/PFKL/PNKP/POM121C/AAAS	75
BP	GO:0150076	neuroinflammatory response	46/7096	75/18670	3.49e-05	0.0009347	0.0006968	IGF1/ITGAM/FPR2/TLR2/NAMPT/GRN/AZU1/PTGS2/CTSC/JAK2/PTPRC/TNF/NUPR1/MIR142/IL1B/AIF1/AGER/LDLR/LRP1/CLU/TYROBP/TTBK1/IL6/LRRK2/CD200R1/BACE2/ADCY1/CST7/ATM/SPHK1/MMP9/MMP3/CNTF/IFNGR1/EGFR/IL18/PSEN1/TLR8/TREM2/IFNG/TLR3/APP/SNCA/CX3CL1/SMO/TLR6	46
BP	GO:0042176	regulation of protein catabolic process	183/7096	381/18670	3.569e-05	0.0009519	0.0007097	CBFA2T3/FYN/TRIM32/EZR/TMTC3/ATG7/SNX1/PINK1/MAD2L2/CTSA/WWP1/WNT5A/BARD1/LRIG2/OAZ2/TIMP2/RNF41/WDR91/FLNA/SMAD7/TNFAIP3/KEAP1/DDRGK1/FBXW7/CTSC/ATRAID/SEC22B/RNF139/LAMP3/BCAP31/HFE/ADAM8/RAD23B/TNF/IRAK3/FHIT/NUPR1/RYBP/APOE/GSK3B/HMGCR/PSME1/MAGEF1/CST3/RNF19B/FBXL5/RELA/EDEM1/CSNK2A2/UBE3A/UBE2K/RDX/ALAD/SGTA/ZFAND2A/SOCS5/PTK2B/CSNK1D/PTTG1IP/LATS1/NRG1/BANP/RNF217/DDB1/FBXL20/OAZ3/CEBPA/PLK2/ANKIB1/GCLC/OPHN1/IL1B/ODC1/PSMC4/FURIN/UQCC2/LDLR/SDCBP/UBE2J1/ARAF/PML/LRP1/CLU/UCHL5/UBE2G2/SNX33/EDEM2/LRRK2/MYCBP2/TIMP4/SUMO1/GLMN/STX5/PTK2/HSPBP1/CSNK1A1/CSNK1E/RNFT1/ARIH2/PLK3/PSME3/DISC1/UBQLN2/ATG4B/NEDD4/TIPARP/CDKN1B/TIMP1/TRIB2/PRKACA/MGAT3/HGS/BBS7/DET1/RHBDD3/NKD2/AZIN1/KLHL40/DERL2/GRIN2C/STUB1/DTL/EEF1A2/NFE2L2/ATXN3/COMMD1/NFE2L1/LAPTM4B/EGFR/YOD1/WWP2/ASB11/CAV3/BAG2/USP7/ANXA2P2/ADAM9/DVL1/MAP1A/WNT1/PSEN1/FMR1/MDM2/MSN/PSMC1/TREM2/UBXN1/IFNG/ARNTL/VIP/OGT/PIN1/CUL4B/RNF185/HSP90AB1/CLEC16A/FOXF2/PSMC2/GPX1/VCP/ANXA2/AURKA/SNCA/SNX9/RBX1/BAG5/AZIN2/LPCAT1/RGP1/USP19/SMARCC1/KCNE2/PSMD1/CHFR/WNT10B/GJA1/RAB26/PSMD3/ERLEC1/OS9/PACSIN3/MAPK9/RHBDF1	183
BP	GO:0051091	positive regulation of DNA-binding transcription factor activity	131/7096	261/18670	3.673e-05	0.0009748	0.0007267	MYD88/S100A9/S100A8/NOD2/S100A12/TRIM32/CX3CR1/TLR2/BCL10/PINK1/WNT5A/STAT3/RNF41/NLRP3/CAMK1D/CD40/DDRGK1/CEBPG/CIB1/FLOT1/RGCC/JAK2/ALK/UBE2N/ADAM8/DVL2/TNF/IRAK3/NFKB1/TRIM13/IL1RAP/KRAS/AIM2/TICAM1/ANXA3/RELA/HCLS1/TRIM37/LRP8/ZBTB7A/IRAK4/TGFB1/IL18R1/LPAR5/TRIM22/CD36/LRRFIP1/SRF/TAB3/TRAF6/NFKB2/TRIM26/IKBKG/TLR4/DDX58/VEGFA/CARD14/CAT/NPM1/IL1B/AGER/CYTL1/DHX9/ARHGEF2/TAF12/BUD31/TNFRSF11A/CRTC2/TRADD/CLU/RBCK1/SAV1/MAVS/IL6/PPARGC1A/FLOT2/CRTC1/ADCY1/EDA/CRTC3/SPHK1/TAB1/TRIM21/TRAPPC9/PRKD2/HDAC4/CTH/ROR1/BEX1/UBC/LGALS9/JMY/FER/RAB7B/TRAF1/CAMK2A/FZD1/EIF2AK2/IL18/MID2/TRAF2/CLOCK/FZD4/NFAM1/WNT1/TRAF5/CAPN3/MAP3K13/FOSL1/TNFSF18/TRIM15/OPRD1/TLR3/PPP2R5B/CARM1/MTDH/PRKCZ/RELN/PRKCQ/HDAC5/MBTPS2/IL18RAP/APP/CX3CL1/FZD2/MALT1/TIRAP/CHUK/WNT10B/SMO/TLR6	131
BP	GO:1901987	regulation of cell cycle phase transition	225/7096	480/18670	3.685e-05	0.0009748	0.0007267	KLF4/TPRA1/PTPN6/ATP2B4/DUSP1/ANXA1/PRKAR2B/TUBA1A/CDKN2D/CDKN1A/NINL/MAD2L2/GPNMB/CCND3/PSMB9/CUL1/RAB11A/MEPCE/PSMB8/DYNC1LI1/DDRGK1/ZNF655/FBXW7/RNASEH2B/RGCC/HUS1B/ATF5/ODF2/PSMA5/SLFN11/PSMD11/EZH2/LSM11/PAF1/SPDL1/PKD2/GIGYF2/HAUS8/PSME1/BTG2/CCND2/TMOD3/GPR132/CNTRL/CDK4/TGFB1/TAOK3/RDX/SIN3A/CEP164/ZNF830/PSMB10/PCM1/MTA3/PSMA1/PSMA4/CSNK1D/CEP131/CENPE/UIMC1/DDB1/TFAP4/DBF4B/SYF2/CDKN2B/PLK2/SFN/KLHL22/NPM1/SFI1/PAFAH1B1/RAD51B/CDK5RAP2/PSMB1/PSMC4/AIF1/NSMCE2/CDKN1C/DONSON/PML/UBE2E1/CEP76/PSMD13/MAPRE1/CDK2AP2/PSMB3/CCND1/CDC23/ESPL1/ZNF207/LCMT1/DDX3X/PSMB5/PSMD6/ATM/TNKS1BP1/CSNK1E/ANAPC5/BUB3/MUC1/HAUS2/PSMC3/KMT2E/CTDSPL/PLK3/PSME3/NACC2/UBE2E2/CCNE1/RAD17/NDC80/BCL2/PCNA/BAX/PSMC6/ANKRD17/ANAPC7/CRADD/ID2/CASP2/CTDSP1/RFWD3/CDKN1B/CDKN2C/MAD2L1BP/PRKACA/CKAP5/DCTN2/CNOT4/FHL1/CDC25A/CEP152/TUBA4A/PLAGL1/GEN1/ARID3A/ZW10/VPS4B/FOXO4/TICRR/UBE2C/BTN2A2/MIIP/DTL/MOS/CEP63/DYRK3/E2F4/CDC26/PLCB1/BRCA1/EGFR/CNOT7/GML/CEP57/ADAM17/RCC2/CETN2/CTDSP2/HAUS5/TUBB4A/HAUS1/RIOK2/MDM2/DLGAP5/YWHAE/PSMC1/ERCC2/ZFP36L2/EIF4G1/CLSPN/WEE1/ANAPC4/RBL2/MTBP/DCUN1D3/PSMD8/PSMA2/FBXL7/TOPBP1/CDC27/FGFR1OP/CDC20/CUL4B/PCID2/TMEM14B/RB1/C10orf99/MEN1/CNOT10/CARM1/YWHAG/JADE1/PSMC5/PKIA/TERT/PSMC2/PSMB2/PSMD4/TRIAP1/AURKA/ANAPC11/BRSK1/APP/CDC73/RBX1/SOX4/BRCC3/CEP78/CCNB3/IK/PSMD1/PAXIP1/PRMT1/ATAD5/WNT10B/PSMB4/STXBP4/ZFYVE19/PSMD9/KIF14/PSMD3/E2F8/ALMS1/SUSD2	225
BP	GO:0070229	negative regulation of lymphocyte apoptotic process	22/7096	29/18670	3.777e-05	0.0009949	0.0007417	TSC22D3/PIP/BCL10/ARG2/BCL6/SLC46A2/MIF/CD74/IL7R/DOCK8/HIF1A/SLC39A10/IDO1/CCL5/IRS2/BMP4/NOC2L/ADA/FADD/PTCRA/PRKCQ/FOXP1	22
BP	GO:1901222	regulation of NIK/NF-kappaB signaling	66/7096	117/18670	3.916e-05	0.001027	0.0007658	NOD2/TLR2/NLRP3/TNFRSF10A/ZFP91/ADIPOR1/BIRC2/ACTN4/TRIP6/NLRP12/AKIP1/TNF/NFKBIA/RELA/IL18R1/NR3C2/PRDX1/TRAF6/TLR4/PTPN22/CARD14/IL1B/AGER/HMGB1/TRADD/RBCK1/BMP7/CHI3L1/CYLD/EDA/SPHK1/HDAC7/EDAR/AGO1/LGALS9/NFAT5/CALR/TNFRSF10B/EIF2AK2/EGFR/IL18/TRAF2/CPNE1/TREM2/HAVCR2/TLR3/CARD10/IL12B/COPS8/LIME1/RHOA/APP/LIMS1/PDCD4/TSPAN6/CCL19/MALT1/TIRAP/TRAF4/HMGB4/NLRC3/IL23A/TLR6/C1QTNF3/SASH1/MIR146A	66
BP	GO:0097193	intrinsic apoptotic signaling pathway	143/7096	289/18670	4.134e-05	0.00108	0.0008053	CRIP1/S100A9/S100A8/BMF/TRIM32/CDKN2D/CDKN1A/SKIL/PINK1/AIFM1/SOD1/ERP29/ZNF622/PTPN2/TMBIM6/PTGS2/PPP1R15A/CUL1/PMAIP1/BCL2A1/MIF/SIAH1/FBXW7/ACKR3/CD44/CEBPB/SHISA5/JAK2/BCAP31/TNF/FHIT/CD74/HMOX1/PTPMT1/NUPR1/ERCC6/CXCL12/ATF4/PDK2/DYRK2/UBE2K/ITPR1/TMEM117/CYP1B1/FIS1/HIF1A/WFS1/HSPB1/MAPK7/PRKCD/PTTG1IP/HNRNPK/USP28/TMEM161A/NDUFS3/MCL1/HTRA2/TMEM109/NCK1/CASP3/SFN/HRAS/ABL1/ENO1/HINT1/ARHGEF2/PML/CLU/PPM1F/SIRT1/SFPQ/ELL3/LCK/CYLD/LRRK2/PLAUR/FLCN/DDX3X/ATM/WWOX/MUC1/AEN/VNN1/BCL2L11/TXNDC12/SERINC3/MYBBP1A/NACC2/IVNS1ABP/MMP9/MLH1/BCL2/BAX/NOC2L/CASP2/SGMS1/DNAJC10/PDK1/CREB3/MLLT11/GSKIP/PDX1/VDAC2/JMY/YBX3/DDIT4/HIPK1/MAP3K5/DNM1L/NFE2L2/TNFRSF10B/BRCA1/RRM2B/TRAF2/CASP4/MDM2/TAF9B/CUL2/BAD/SNAI1/BCLAF1/RAD9A/PPP1R13B/MOAP1/DNAJA1/HYOU1/DIABLO/MSX1/POLB/GPX1/TOPORS/TRIAP1/ERN1/DAPK2/BAG5/PDCD10/BAK1/BCL2L2/ATAD5/CD24/HIC1/FIGNL1/DDIAS	143
BP	GO:0033673	negative regulation of kinase activity	129/7096	257/18670	4.179e-05	0.001088	0.0008108	ITPRIP/PTPN6/DUSP1/PRKAR2B/CDKN2D/CDKN1A/SOCS3/DUSP6/LYN/PPP2CA/FABP4/DUSP5/CSK/PTPN2/NUP62/CHP1/DUSP10/TNFAIP3/CIB1/RGS2/UCHL1/DUSP7/COX11/GSTP1/PTPRC/IRAK3/EPHB2/TESC/APOE/HMGCR/KAT2B/DUSP3/LRP5/HEXIM1/TAOK3/GADD45B/CBLB/GNAQ/DUSP18/SOCS5/HSPB1/ZFYVE28/HEG1/PRKCD/LATS1/PKIB/GMFG/ZGPAT/HYAL2/PIK3IP1/MBIP/DUSP2/TFAP4/PTPN22/ADARB1/CEBPA/DUS2/IGF1R/NCK1/CDKN2B/CASP3/SFN/NPM1/ABL1/PAK2/IL1B/DTNBP1/MVP/PTK6/CDKN1C/PAQR3/SH3BP5L/PPM1F/SIRT1/HEXIM2/BMP7/DUSP19/IRS2/SMYD3/SNX6/DUSP14/RGS3/DUSP4/PRKAG2/TARBP2/BMP4/INPP5K/RGS14/CDKN1B/CDKN2C/TSG101/TRIB2/AKT1S1/CD300A/GSKIP/LAX1/SPRY1/CORO1C/RHOH/VPS25/SPRED1/CAV3/CHORDC1/SPRY2/DVL1/DEPTOR/PSEN1/IPO7/SMCR8/NPRL2/SOCS1/IFNG/HIPK3/FGFR1OP/LATS2/DNAJA1/SMPD1/RB1/MEN1/YWHAG/PKIA/GPS1/ITGB1BP1/PDCD4/ADAR/AIDA/CEP85/TAF7/PTPRJ	129
BP	GO:0045621	positive regulation of lymphocyte differentiation	55/7096	94/18670	4.28e-05	0.001109	0.000827	PNP/NFKBIZ/LILRB2/ANXA1/EGR3/BCL6/NLRP3/DUSP10/IL4R/CBFB/PTPRC/IL15/ADAM8/CD74/IL7R/AXL/TGFB1/SOCS5/LILRB4/ZBTB1/FLT3LG/ZBTB7B/NFKBID/RASGRP1/PIK3R6/IL7/TESPA1/HLA-G/TOX/CYLD/VNN1/PPP2R3C/IL12RB1/LGALS9/BTN2A2/MMP14/ADA/HLX/IL18/AP3B1/TNFSF4/SART1/SOCS1/BAD/IFNG/PCID2/IL12B/PRKCZ/CD80/RHOA/CD83/CCL19/MALT1/ZBTB16/IL23A	55
BP	GO:0007033	vacuole organization	87/7096	163/18670	4.5e-05	0.001157	0.0008625	SRPX/HEXB/GRN/ATG7/PINK1/ATG3/C9orf72/TPP1/NAGLU/FAM160A2/HPS4/FEZ2/ULK2/ATG14/SEC22B/P2RX7/NUPR1/VPS41/CHMP4B/CLN8/ARSB/RAB23/MAP1LC3A/ATG101/NAGPA/ZKSCAN3/CORO1A/TFEB/GNPTAB/HPS1/TP53INP2/UBXN2B/TMEM41B/FIG4/RAB3GAP1/ABCA1/LAMTOR1/CLN3/NSFL1C/VPS33A/RAB20/ATG13/WIPI1/NPRL3/HOOK2/TMEM106B/RAB33B/LRRK2/MAP1LC3C/CLVS2/ARF1/ATG9A/PHF23/UBQLN2/HOOK3/VPS18/ATG4B/PACS2/MFSD8/RAB5A/ATG2B/WDR45B/CLN6/CLN5/VPS4B/RAB7B/LAPTM4B/ULK1/ANXA2P2/PSEN1/MTMR3/STX12/SH3GLB1/IFT20/SMCR8/NPRL2/GAA/ATG16L2/GABARAPL1/SCFD1/RNF5/ATG4A/VPS16/TRAPPC8/ANXA2/MBTPS1/ATG12	87
BP	GO:1903555	regulation of tumor necrosis factor superfamily cytokine production	87/7096	163/18670	4.5e-05	0.001157	0.0008625	IGF1/NOD2/CCR2/TLR1/CX3CR1/TLR2/PTPN6/IL27RA/ACP5/CLEC7A/ZFP36/WNT5A/AZU1/ARG2/GPNMB/SYT11/LILRA5/TNFAIP3/MIF/CD2/LY96/LILRA2/JAK2/GSTP1/PTPRC/ADAM8/IRAK3/LILRB1/SLAMF1/TICAM1/AXL/PTAFR/HSPB1/CD36/FRMD8/LEP/TLR4/DDX58/PTPN22/HLA-E/CACTIN/AGER/RASGRP1/DHX9/ARHGEF2/UBE2J1/HMGB1/CLU/TYROBP/MAVS/LRRK2/DICER1/HDAC2/AKAP8/IFIH1/MAPKAPK2/CD47/GPR18/CD274/LGALS9/CYBA/CYBB/FZD5/IFNGR1/FADD/PSEN1/TREM2/HAVCR2/IFNG/CD34/TLR3/LBP/IL12B/ZBTB20/CD33/FOXP1/C5AR2/APP/CX3CL1/CCL19/TIRAP/HMGB4/NR1H4/NLRC3/IL23A/GHRL/PTPRJ	87
BP	GO:0007050	cell cycle arrest	120/7096	237/18670	4.667e-05	0.001195	0.0008911	DUSP1/CDKN2D/CDKN1A/MAPK12/SKIL/NOTCH2/IRF1/BARD1/PPP1R15A/STRADB/MIF/GAS2L1/MAP2K1/CAB39L/MYC/RGCC/PKD2/BTG2/KAT2B/GAS7/ZNF268/CDK4/TGFB1/VASH1/TFAP4/FZD9/ZBTB49/SETMAR/CDKN2B/CDK5/PLK2/SFN/HRAS/ABL1/KLLN/LAMTOR1/CDKN1C/PML/RRAGD/HMGN5/CCND1/MLST8/CDK9/EIF4G2/UHRF2/ATM/TNKS1BP1/MIR34A/MUC1/WDR6/KMT2E/PRKAG2/MYOG/PLK3/MYBBP1A/LAMTOR4/PCNA/BAX/CRADD/ID2/CASP2/MLF1/CDKN1B/CDKN2C/CCNK/TSG101/KIF20B/PRKACA/CNOT4/INHBA/PLAGL1/ARID3A/JMY/FOXO4/EVI2B/HBP1/RRAGA/CALR/SDE2/TBRG4/LAMTOR5/MED25/E2F4/BRCA1/CNOT7/GML/SLC25A33/CGRRF1/PRKAA1/MDM2/GADD45GIP1/TCF7L2/RBL2/MTBP/IFNG/PRKAG1/HSP90AB1/RB1/INHA/PPP2R5B/ING4/CNOT10/CARM1/IL12B/EIF2AK4/MTOR/TRIAP1/AURKA/ERN1/SOX4/PNPT1/PPM1G/STRADA/PRMT1/WNT10B/BIN1/SLC38A9/E2F8/DDIAS/PRKAB1	120
BP	GO:0008360	regulation of cell shape	81/7096	150/18670	4.741e-05	0.001209	0.0009016	CDC42EP4/FN1/FYN/EZR/HEXB/ANXA1/CDC42SE1/ARHGEF18/FMNL3/FMNL1/LST1/ARAP1/DIAPH1/HCK/FBLIM1/RHOC/FGD6/FGD5/RND3/PLXNB2/RDX/CDC42EP2/PARVB/PTK2B/PLEKHO1/PLXNC1/CORO1A/RHOG/BAIAP2/SEMA4A/ITGA7/CDC42SE2/FGR/VEGFA/ATP10A/ALDOA/S100B/SEMA4D/PHIP/CRK/CCL7/CDC42EP3/CYFIP1/S100A13/RHOU/PTK2/MYH9/PLXNA1/CCL13/PLXND1/PRPF40A/TPM1/WDPCP/ERMN/MARK2/RHOQ/ARHGAP18/RHOV/RHOF/LPAR1/DMTN/ZMPSTE24/RHOH/MKLN1/GNA13/EPB41/MSN/MYO10/FGD3/EPB42/RHOBTB3/PLXNA3/SPTA1/PLXNA2/FGD4/CSF1R/HPN/RHOA/DAG1/CCL24/P2RY1	81
BP	GO:0008654	phospholipid biosynthetic process	130/7096	260/18670	4.924e-05	0.001251	0.0009328	FPR2/HTR2B/LPCAT2/SLC27A1/CDS1/HEXB/PLA2G12A/SGMS2/CHPT1/DGKA/CAPN2/GPAM/PLSCR1/PPARD/PLEKHA1/MBOAT7/MTMR12/PIGV/CDS2/PIGP/PTDSS2/MBOAT1/PTPMT1/PIGK/LPGAT1/PIK3R3/PTPN13/PLD1/PNPLA3/SACM1L/CSNK2A2/HMGCS1/PIGN/STARD10/SYNJ1/PITPNM1/DDHD1/SERINC1/FIG4/SPTLC2/AGPAT3/SAMD8/PLCG2/PIK3R6/FDPS/CSNK2B/PIGF/IDH1/SYNJ2/STARD7/CDIPT/FABP3/PIGB/DPM1/OCRL/PDGFB/ABHD3/AGPAT4/GPAA1/SH3YL1/RAB38/ATM/ARF1/DOLK/CRLS1/PIGM/MFSD2A/PLEKHA8/IDI1/MBOAT2/SBF1/LCAT/MTMR4/MPPE1/INPP5K/MTMR6/PIK3CD/SGMS1/PI4K2A/RAB5A/PIGQ/ACP6/MTMR2/INPP5F/DOLPP1/PDGFA/FAR1/PIGO/CHKA/PIGH/FABP5/AGK/NUS1/DHDDS/AGPAT5/SRD5A3/PLD2/CPNE1/DPM3/MTMR3/PLEKHA3/APOA1/PLA2G6/PIGT/GNPAT/CPNE3/MTMR9/SLC44A2/TMEM38B/PIK3CG/SERAC1/AGPAT1/PIP5K1B/CHAT/TAZ/VAC14/LPCAT1/CHKB/PGS1/AGPAT2/PGAP3/INPPL1/NR1H4/ARF3/PGAP1/DPAGT1/PIK3CB/IMPA1/PI4KB/LPCAT3	130
BP	GO:1903578	regulation of ATP metabolic process	68/7096	122/18670	5.059e-05	0.00128	0.0009545	IGF1/CBFA2T3/PINK1/FBP1/PGK1/STAT3/PFKFB3/NUP62/NUP160/NUP214/SLC2A6/P2RX7/NUPR1/PGAM1/EIF6/ZBTB7A/NUP85/HIF1A/ISCU/SEH1L/INSR/NUP43/ENO1/DNAJC30/UQCC2/POM121/PFKFB4/PPARGC1A/FLCN/COX7A2L/SLC25A12/SHMT2/PRKAG2/MYOG/NCOR1/PFKFB1/NUP88/HDAC4/NUP107/DDIT4/PGK2/PFKFB2/ARNT/DNM1L/SLC25A33/PPARA/NUP93/PRKAA1/PSEN1/DNAJC15/NUP205/PID1/TREM2/NUP50/IFNG/PRKAG1/OGT/ATP7A/ESRRB/ZBTB20/VCP/RHOA/TAZ/APP/SNCA/ABCD1/POM121C/AAAS	68
BP	GO:0036294	cellular response to decreased oxygen levels	111/7096	217/18670	5.1e-05	0.001286	0.0009586	SLC8A1/EPAS1/KCNMB1/NAMPT/PINK1/RBPJ/PGK1/AIFM1/LMNA/TSC1/TMBIM6/PTGS2/PSMB9/PPARD/GNB1/PMAIP1/PSMB8/SIRT4/MYC/RGCC/EGR1/PSMA5/ADAM8/PSMD11/HMOX1/SLC9A1/PSME1/SUV39H2/ATF4/HIGD1A/HIF1A/PSMB10/PSMA1/PSMA4/VEGFA/EGLN1/ENO1/PSMB1/PSMC4/S100B/PSMD13/PSMB3/SIRT1/BMP7/NDRG1/HIF1AN/EGLN3/PPARGC1A/CITED2/PSMB5/PSMD6/MIR34A/PSMC3/PLK3/COX4I2/SUV39H1/PSME3/BCL2/PSMC6/CPEB1/PDK1/UBC/CYBB/KCNK2/ARNT/STUB1/DNM1L/NFE2L2/DNMT3A/AQP3/MALAT1/ACAA2/PRKAA1/MDM2/PSMC1/CUL2/BAD/CHCHD2/PSMD8/RORA/TBL2/PSMA2/ATP7A/BACH1/CLCA1/HYOU1/OPRD1/CD34/CCNA2/CACNB3/PSMC5/TERT/PSMC2/PSMB2/PSMD4/MTOR/PICK1/RBX1/USP19/PSMD1/SLC8A3/ROCK2/ENDOG/PSMB4/UCN3/MGARP/PSMD9/PSMD3/CPEB2/FOXO3/MIR146A	111
BP	GO:0008361	regulation of cell size	94/7096	179/18670	5.211e-05	0.001309	0.0009756	RTN4R/FN1/KCNN4/DPYSL2/WNT5A/TSC1/SEMA4B/SPP1/RAB11A/ULK2/P2RX7/IFRD1/APOE/GSK3B/CXCL12/TMEM123/IL7R/CDK4/TWF2/RDX/SIN3A/CLN8/PAK1/MEGF8/SRF/SCTR/SEMA4A/VEGFA/CDK5/TNFRSF12A/CLCN3/ABL1/PAFAH1B1/GDI1/SEMA4C/SLC12A9/SEMA4D/LRP1/CREB1/RAC1/DCC/CYFIP1/GNB3/SLC12A2/SEMA6B/SLC12A8/LAMTOR4/NRP1/DISC1/SEMA3B/DNM2/L1CAM/PRR16/LPAR3/IST1/NDEL1/OLFM1/AKT1S1/PLEK/WDR36/SEMA5A/FSTL4/LAMTOR5/E2F4/LRRC8A/VAV1/CAV3/DEPTOR/SEMA5B/MSN/MAP3K13/RUFY3/PLXNA3/ATP7A/CLNS1A/RET/HSP90AB1/SLC12A1/SLC12A7/MTOR/KCNMA1/RHOA/TRPV4/RTN4/SLC12A4/CRABP2/FGF13/SHANK3/KEL/MACF1/TRPV2/TRIM46/SLC12A6/BMPR2	94
BP	GO:0042326	negative regulation of phosphorylation	219/7096	468/18670	5.303e-05	0.001326	0.0009885	KLF4/MYADM/ITPRIP/CBFA2T3/EZR/PTPN6/DUSP1/PRKAR2B/CDKN2D/CDKN1A/SOCS3/DUSP6/LYN/PINK1/FBP1/PPP2CA/FABP4/DUSP5/CSK/GBP1/C9orf72/STAT3/PTPN2/NUP62/CHP1/SMAD7/DUSP10/ZBED3/TNFAIP3/CIB1/RGS2/ATG14/UCHL1/MYC/DUSP7/COX11/NLRP12/RNF149/GSTP1/PTPRC/P2RX7/IRAK3/EPHB2/NUPR1/PEBP1/TESC/APOE/HMGCR/MICAL1/KAT2B/PTPN13/DUSP3/LRP5/PBLD/HEXIM1/NDRG2/LDLRAD4/TGFB1/TAOK3/GADD45B/HGF/ARRB1/CBLB/GNAQ/DUSP18/SOCS5/HSPB1/ZFYVE28/RANBP9/HEG1/PRKCD/LATS1/PKIB/GMFG/ZGPAT/HYAL2/PIK3IP1/MBIP/DUSP2/TFAP4/TLR4/PTPN22/ADARB1/CEBPA/DUS2/IGF1R/NCK1/CDKN2B/CASP3/CACTIN/SFN/NPM1/ABL1/PAFAH1B1/PAK2/IL1B/PMEPA1/DTNBP1/MVP/PTK6/CDKN1C/PAQR3/SEMA4D/DMD/SH3BP5L/PPM1F/SIRT1/HEXIM2/PPP1R15B/BMP7/DUSP19/IRS2/CYLD/LRRK2/SMYD3/PPARGC1A/SPINK1/FLCN/ANKLE2/SNX6/DUSP14/RGS3/DUSP4/PRKAG2/MYOG/NCOR1/CTDSPL/GFRA2/ASH1L/STRAP/PFKFB1/TARBP2/BMP4/TNIP1/BAX/INPP5K/RGS14/HDAC4/CTDSP1/CDKN1B/CDKN2C/TSG101/TRIB2/CHRNA10/ZMYND11/DNAJC10/INHBA/AKT1S1/CD300A/GSKIP/INPP5F/LAX1/DDIT4/RABGEF1/BTN2A2/AMBP/DMTN/SPRY1/CORO1C/RHOH/VPS25/PWP1/IMPACT/SPRED1/PPARA/CTDSP2/CAV3/SLIT2/CHORDC1/SPRY2/DVL1/DEPTOR/PSEN1/DNAJC15/IPO7/PID1/SMCR8/NPRL2/SOCS1/EIF4G1/PPEF2/IGBP1/IFNG/HIPK3/FGFR1OP/LATS2/DNAJA1/PIN1/BDKRB1/SMPD1/RB1/INHA/MEN1/YWHAG/TRAF3IP1/PKIA/PRKCZ/PRDM15/MTOR/GPS1/RHOA/DAG1/SNCA/ITGB1BP1/ENG/PDCD4/ADAR/BAK1/AIDA/UBE2B/GREM1/NNT/TARDBP/CEP85/WNK2/CD109/TAF7/PTPRJ/MIR146A	219
BP	GO:0006140	regulation of nucleotide metabolic process	79/7096	146/18670	5.326e-05	0.001326	0.0009885	IGF1/CBFA2T3/PDK4/PINK1/FBP1/PGK1/STAT3/PFKFB3/NUP62/NUP160/NUP214/SLC2A6/ME1/P2RX7/NUPR1/PGAM1/PDK2/EIF6/ZBTB7A/NUP85/HIF1A/ISCU/SEH1L/INSR/NUP43/ENO1/DNAJC30/GSTZ1/UQCC2/POM121/PFKFB4/PPARGC1A/FLCN/COX7A2L/SLC25A12/SHMT2/PRKAG2/MYOG/NCOR1/ADORA2B/PFKFB1/NUP88/HDAC4/NUP107/PDK1/DDIT4/PGK2/PFKFB2/ARNT/DNM1L/PDP2/SLC25A33/PPARA/NUP93/PRKAA1/PSEN1/DNAJC15/NUP205/PID1/TREM2/NUP50/IFNG/PRKAG1/OGT/ATP7A/PDP1/ESRRB/ZBTB20/CDA/VCP/ME2/RHOA/TAZ/APP/SNCA/ABCD1/PDPR/POM121C/AAAS	79
BP	GO:0071706	tumor necrosis factor superfamily cytokine production	89/7096	168/18670	5.341e-05	0.001326	0.0009885	IGF1/NOD2/CCR2/TLR1/CX3CR1/TLR2/PTPN6/IL27RA/ACP5/CLEC7A/BCL10/ZFP36/WNT5A/AZU1/ARG2/GPNMB/SYT11/LILRA5/TNFAIP3/MIF/CD2/LY96/LILRA2/JAK2/GSTP1/PTPRC/ADAM8/IRAK3/LILRB1/SLAMF1/TICAM1/AXL/PTAFR/HSPB1/CD36/FRMD8/LEP/TLR4/DDX58/PTPN22/HLA-E/CACTIN/AGER/RASGRP1/DHX9/ARHGEF2/UBE2J1/HMGB1/CLU/TYROBP/MAVS/LRRK2/DICER1/AZI2/HDAC2/AKAP8/IFIH1/MAPKAPK2/CD47/GPR18/CD274/LGALS9/CYBA/CYBB/FZD5/IFNGR1/FADD/PSEN1/TREM2/HAVCR2/IFNG/CD34/TLR3/LBP/IL12B/ZBTB20/CD33/FOXP1/C5AR2/APP/CX3CL1/CCL19/TIRAP/HMGB4/NR1H4/NLRC3/IL23A/GHRL/PTPRJ	89
BP	GO:0001914	regulation of T cell mediated cytotoxicity	24/7096	33/18670	5.391e-05	0.001328	0.00099	STX7/CD1C/PTPRC/P2RX7/CD1E/LILRB1/IL7R/PPP3CB/FAM49B/HLA-F/HLA-E/HLA-B/AGER/CD1B/HLA-G/HLA-C/PVR/CD1D/IL12RB1/CD1A/FADD/HLA-A/IL12B/IL23A	24
BP	GO:0019692	deoxyribose phosphate metabolic process	24/7096	33/18670	5.391e-05	0.001328	0.00099	DGUOK/NEIL2/UNG/NUDT1/NT5C/ADK/CDADC1/GUK1/SAMHD1/CMPK2/TDG/PGM2/DERA/TYMS/ADA/SHMT1/TBPL1/DCTD/DCTPP1/NT5M/DUT/NUDT16/MBD4/SMUG1	24
BP	GO:0031667	response to nutrient levels	232/7096	499/18670	5.421e-05	0.00133	0.0009918	NQO1/SLC8A1/VDR/NOD2/FYN/USF2/NAMPT/PDK4/UPP1/CDKN2D/CDKN1A/APPL2/LDHA/BCL10/ATG7/ZFP36/GCLM/POR/AIFM1/TSC1/CHSY1/SOD1/TMEM135/SRD5A1/PIM1/DAD1/TMBIM6/KLF10/PTGS2/SPP1/LRP11/PPARD/SLC25A25/HMGCL/PMAIP1/PSPH/GAS2L1/ULK2/STAT1/AHCY/SIK1/ATG14/FOLR2/LAMP2/GDAP1/GSTP1/IL15/FAS/P2RX7/HFE/HAT1/HMOX1/CXCL10/AKR1C3/APOE/AGL/HMGCR/TBC1D5/ATF4/PKM/RELA/PDK2/NUCB2/WDR24/HIGD1A/TGFB1/ARSB/AACS/HMGCS1/ALAD/XPR1/FIS1/MAP1LC3A/SEH1L/PCK2/PANX1/LEP/BCL11A/SRF/MBD1/BAIAP2/SCTR/MBD3/ADRB1/ACSL4/HSPA5/HNRNPA1/CDKN2B/CAT/PPM1D/OMA1/GCLC/ABCA1/IL1B/LDLR/SIK2/RRAGD/ACACB/P2RY12/WIPI1/NPRL3/CREB1/BBS2/IGFBP2/SIRT1/TRPM4/BMP7/MKKS/CCND1/EIF2S1/KPTN/LRRK2/G6PD/PPARGC1A/MAP1LC3C/KYNU/SPARC/BBS4/NMRAL1/OXCT1/ATG9A/FNIP1/ZFYVE1/TRIM24/P2RX1/NMUR2/MYBBP1A/MAPK8/SIRT5/PFKFB1/BCL2/HTR4/GNAI2/PCNA/CYP26B1/BCAS3/ERCC1/ASNS/RMI1/ADRB2/SLC16A1/SETDB1/ITGA2/GSS/WDR45B/TYMS/CTSV/PDX1/FOXK2/CYBA/CYBB/TNRC6A/SREBF2/SORD/FOXO4/MAP3K5/RRAGA/ADA/UCP1/DNM1L/NFE2L2/IMPACT/EIF2AK2/ULK1/EGFR/DSC2/ITFG2/TPH2/PPARA/AMIGO1/SESN1/DNMT3A/HSP90B1/AQP3/ADIPOR2/GIPR/KAT2A/PRKAA1/DNAJC15/HAMP/MDM2/MAPK1/MTMR3/P2RY4/APOA1/SH3GLB1/EIF2AK1/CYP27B1/NPRL2/EIF4G1/DAP/EIF2A/BCKDHB/CAD/TBL2/GNPAT/OGT/DAPL1/GABARAPL1/CD4/CLEC16A/CACNB3/WNT2B/CYP26A1/EIF2AK4/CADPS2/MTOR/TRPV4/PICK1/GHRH/DEPDC5/P2RX2/CIB2/SSH1/MGMT/SPX/CD3E/NENF/FGF23/MPO/ALDH3A1/NNT/NR1H4/SESN2/UCN3/P2RY1/G6PC/FOXO3/GHRL/ALB/BMPR2/P2RX5	232
BP	GO:0006487	protein N-linked glycosylation	47/7096	78/18670	5.473e-05	0.001332	0.000993	PGM3/MCFD2/MGAT2/DAD1/MGAT5/MAN1C1/MGAT4B/STT3A/ALG2/KRTCAP2/OST4/PMM2/UBE2J1/ALG6/UBE2G2/DPM1/RPN2/DOLK/STT3B/NUDT14/ALG12/ALG10/MGAT3/ASGR2/LMAN1/DOLPP1/MGAT5B/ALG13/MOGS/TUSC3/TMEM258/NUS1/DHDDS/SRD5A3/GFPT1/DPM3/ST3GAL1/ASGR1/VCP/B3GALT5/GFPT2/B4GALT1/ALG14/DDOST/DPAGT1/ALG8/ALG3	47
BP	GO:0016050	vesicle organization	158/7096	325/18670	5.475e-05	0.001332	0.000993	SRPX/S100A10/SERPINA1/F5/STAM/ANXA1/STX7/STX11/DNM3/MCFD2/BLOC1S2/GNAI3/RAB11A/FAM160A2/HPS4/KLHL12/RFX2/TAP2/SNX10/TAP1/CTSC/ALS2/SEC22B/SQSTM1/AGFG1/SAMD9L/P2RX7/CD59/C2CD5/AQP11/VPS37B/ZEB2/ANKRD28/VPS41/CHMP4B/STXBP1/UNC13B/SAR1B/TRAPPC6A/SYNJ1/CSNK1D/PPP6R1/CORO1A/TMCC1/CNIH3/HPS1/TRAPPC5/VAMP3/CLCN3/SAMD9/PAFAH1B1/ASIP/CTSZ/ARFGAP3/ABCA1/TMED10/DTNBP1/LAMTOR1/VPS37C/VTA1/SDCBP/RAB20/BLOC1S6/ANKRD27/BET1/CREB1/VAPB/RAB8A/DOC2B/HOOK2/GOSR2/SNX33/GOSR1/RAB32/RAB38/TAPBP/STX5/SAR1A/ARF1/PPP6C/TMEM127/SPHK1/PLA2G3/DNM1/TRAPPC6B/HOOK3/VPS18/TRAPPC9/GOLPH3L/BCL2/NAPA/DNM2/TBC1D20/BLOC1S3/CHMP2A/TXNDC8/COL7A1/TSG101/PI4K2A/IST1/HGS/STX16/GPR143/KIF13A/LMAN1/NKD2/VTI1A/CHMP1A/PEF1/VPS4B/CD2AP/RAB7B/CORO1C/F2R/BLOC1S1/CALR/BLOC1S4/VPS25/ACRBP/LAPTM4B/INSIG1/SEC23IP/RAB8B/TRAPPC2L/AP3B1/TBPL1/ANXA2P2/AP1G1/RAB22A/TRAPPC3/SRGN/RAB3A/STX12/VTI1B/SYT9/AP1M1/SNX19/STX8/SYT1/KIF5B/CD34/SCFD1/VPS16/VAMP1/ALS2CL/SNAP29/SYT4/AP2M1/ANXA2/SNCA/CHMP1B/PICALM/PREB/SEC24A/RAB27A/VPS8/SEC31B/SEC16B	158
BP	GO:0016570	histone modification	213/7096	454/18670	5.489e-05	0.001332	0.000993	USP51/USP3/SPI1/PINK1/SKI/BAZ1A/LMNA/JMJD6/DR1/BCL6/PHF19/EYA3/CHTOP/ENY2/KDM1B/PER2/DPY30/JAK2/SETDB2/LDB1/MORF4L2/UBE2N/ZNF304/EZH2/HAT1/PAF1/WDR5B/UHRF1/RYBP/DOT1L/SUPT7L/KAT2B/MRGBP/SUV39H2/TET2/TRIM16/TRIM37/TGFB1/KDM7A/SIN3A/ZNF451/JADE3/ARRB1/NCOA3/PRMT9/MTA3/PCGF2/PRKCD/RUVBL2/ATXN7L3/RUVBL1/UIMC1/EPC2/MBIP/NSD1/DDB1/PCGF1/MSL3/ZBTB7B/MBD3/PCGF3/HSF4/KAT7/SETMAR/VEGFA/CDK5/YEATS4/SETD5/TAF5L/KDM2A/SIRT7/IL1B/PRDM4/HDAC11/MAP3K12/UBR5/KAT8/MIER1/TAF12/UBE2E1/UBE2A/CRTC2/SMARCAD1/PPM1F/SIRT1/SFPQ/ATXN7/NAA40/SIN3B/SETD7/BRD8/PAXBP1/SUDS3/CDK9/LRRK2/TAF5/SMYD3/PPARGC1A/FLCN/BCOR/MCRS1/BRMS1L/KDM4B/ATM/DTX3L/MUC1/HDAC10/FBL/KMT2E/HDAC2/NTMT1/AKAP8/KAT5/HDAC7/SUV39H1/MAPK8/NACC2/ASH1L/USP16/PRKD2/ELP3/KDM2B/SETD6/KDM8/BRPF1/NOC2L/HDAC4/DPF2/CTCF/SETDB1/RSF1/PADI1/PHF20/KDM5B/PRMT5/KDM6B/COPRS/ZMPSTE24/RING1/KDM4D/LEO1/RNF20/TAF6L/PWP1/CAMK2D/BRCA1/ING3/KANSL1L/CLOCK/USP7/ELK4/EPC1/KAT2A/PRKAA1/FMR1/PHF10/PADI3/PHC1/VRK1/DDB2/EYA4/CPA4/TAF9B/USP49/PRDM2/EID1/PRDM6/OGT/BAP1/KDM5C/MCM3AP/CUL4B/RLF/CCNA2/FBLL1/JDP2/ING4/SET/MEN1/CARM1/JADE1/TBL1X/KMT2B/HDAC5/AURKA/USP22/CDC73/SNCA/MSL1/PAX7/BRCC3/PAX5/POLE4/GCG/EZH1/TADA3/MTA2/PAXIP1/PRMT1/ACTL6A/ATXN3L/UBE2B/WDR82/NR1H4/KAT6B/PRKCA/WDR5/TET1/TAF7/KDM4A/BRMS1/ZNF335/NAA60	213
BP	GO:0001959	regulation of cytokine-mediated signaling pathway	93/7096	177/18670	5.545e-05	0.00134	0.0009992	TRIM32/PTPN6/IL1R2/SOCS3/IRF7/PARP9/WNT5A/PTPN2/TNFAIP3/NLRC5/BIRC2/CREBRF/STAT1/CBFB/JAK2/GSTP1/PTPRC/TNF/IRAK3/CD74/YTHDF3/VRK2/IFNGR2/AXL/CDC37/UBE2K/HIF1A/NR1H2/METTL3/SPPL2A/IKBKG/CACTIN/PAFAH1B1/CASP8/SAMHD1/CCL5/MMP12/CD300LF/RNF113A/SPATA2/IL7/TRADD/RBCK1/IL1RN/IL1R1/MAVS/ELF1/IL6/CYLD/LSM14A/SUMO1/OTUD4/SPHK1/BIRC3/NR1H3/CASP1/RNASEL/RFFL/ZBP1/RABGEF1/HIPK1/TRAF1/IFNGR1/CNOT7/MUL1/FADD/ADAM17/TRAF2/CASP4/SLIT2/CPNE1/TAX1BP1/SIGIRR/APOA1/SOCS1/TREM2/IL3/TSLP/IFNG/JAK1/TXK/PALM3/HSP90AB1/IFNAR2/TRIM6/AGPAT1/CLIP3/ADAR/CHUK/AGPAT2/NR1H4/CD24/SLIT3	93
BP	GO:2001236	regulation of extrinsic apoptotic signaling pathway	83/7096	155/18670	5.719e-05	0.001377	0.001027	SRPX/IGF1/ITPRIP/FYN/PEA15/SKIL/BCL10/GCLM/LMNA/TNFRSF10A/SH3RF1/STRADB/PMAIP1/EYA3/TNFAIP3/GSTP1/PTPRC/FAS/TNF/HMOX1/PDIA3/TMC8/RELA/HGF/CTNNA1/MAPK7/FEM1B/HYAL2/MCL1/HTRA2/TNFRSF12A/SP100/TNFSF10/GCLC/CASP8/PAK2/IL1B/DEDD2/ARHGEF2/PML/PHIP/IL7/TRADD/RAF1/RBCK1/G0S2/CYLD/WWOX/BMP5/NRP1/PSME3/BCL2/BMP4/SERPINE1/HMGB2/IL1A/ZMYND11/INHBA/UNC5B/RFFL/TRAF1/TNFRSF10B/PPP1CA/PPP2R1B/BRCA1/FADD/COL2A1/TRAF2/ZC3HC1/DEPTOR/TCF7L2/EYA4/FAIM2/RET/ZSWIM2/MAP2K5/DBH/TERT/GPX1/CX3CL1/FAIM/BMPR1B/SIAH2	83
BP	GO:0032623	interleukin-2 production	39/7096	62/18670	6.082e-05	0.001459	0.001088	PNP/CCR2/EZR/ANXA1/CLEC7A/ZFP36/SLC11A1/GBP1/TNFAIP3/PTPRC/IL1RAP/TRAF6/IL20RB/PDE4B/ABL1/IL1B/HOMER3/SPTBN1/GLMN/VSIG4/KAT5/HDAC7/PRKD2/CD247/IL1A/LAG3/IL18/TRAF2/HAVCR2/CD34/CD4/CD80/TBX21/PRKCQ/NAV3/CD83/MALT1/CD3E/NR1H4	39
BP	GO:0001916	positive regulation of T cell mediated cytotoxicity	20/7096	26/18670	6.149e-05	0.001466	0.001093	STX7/CD1C/PTPRC/P2RX7/CD1E/FAM49B/HLA-F/HLA-E/HLA-B/CD1B/HLA-G/HLA-C/PVR/CD1D/IL12RB1/CD1A/FADD/HLA-A/IL12B/IL23A	20
BP	GO:0009262	deoxyribonucleotide metabolic process	25/7096	35/18670	6.156e-05	0.001466	0.001093	DGUOK/NEIL2/UNG/NUDT1/NT5C/ADK/CDADC1/GUK1/SAMHD1/CMPK2/TDG/DERA/TYMS/RRM2/ADA/SHMT1/TBPL1/RRM2B/DCTD/DCTPP1/NT5M/DUT/NUDT16/MBD4/SMUG1	25
BP	GO:0009205	purine ribonucleoside triphosphate metabolic process	162/7096	335/18670	6.288e-05	0.001492	0.001112	IGF1/CBFA2T3/HK3/LDHA/PINK1/FBP1/PGK1/VPS9D1/STAT3/PFKFB3/NUP62/NUP160/PFKM/UQCRC2/GNAI3/PFKP/GAPDH/SLC25A25/NUP214/SLC2A6/P2RX7/UQCR11/NDUFA8/NUPR1/RAN/AK3/PGAM1/AK2/PKM/GALK1/NFS1/EIF6/TPI1/ZBTB7A/NDUFC1/TGFB1/RAB23/NUP85/CLPX/HIF1A/ISCU/SEH1L/NDUFB11/INSR/ALDOC/MBIP/NDUFS3/GUK1/NUP43/IMPDH1/NDUFA3/NMNAT1/ATP6V1A/ENO1/DNAJC30/ALDOA/UQCC2/NDUFA11/PARG/POM121/OGDH/CHCHD10/MOCS2/UQCR10/COX7C/GPI/ATP6V1B2/LRRK2/PFKFB4/PPARGC1A/FLCN/COX7A2L/DHTKD1/NME3/NDUFA4/SLC25A12/SHMT2/LDHC/NME4/PRKAG2/MYOG/NCOR1/COX4I2/NDUFA1/GTPBP1/PFKFB1/NUP88/HDAC4/ATP1B1/RHOQ/NME1/NUDT5/TEFM/COQ9/NUP107/COA6/COX15/NDUFA10/FOXK2/NDUFB1/DDIT4/NDUFB5/UQCRQ/PGK2/PFKFB2/MOCS3/ARNT/DNM1L/NDUFS1/SLC25A33/PPARA/NUP93/SLC25A13/NDUFB8/PRKAA1/PSEN1/DNAJC15/NUP205/ENO2/PID1/SURF1/NDUFB6/BAD/SLC4A1/TREM2/NUP50/IFNG/PRKAG1/OGT/ATP7A/NDUFB3/SDHA/ESRRB/ZBTB20/VCP/NDUFS7/ADPGK/NDUFV2/ND4/SDHD/RHOA/TAZ/APP/SNCA/UQCRB/ATP6V1B1/AMPD3/ABCD1/NDUFB2/SDHAF2/GIMAP7/MYH3/COX6C/ATP1A2/PFKL/CTNS/NDUFS2/POM121C/AAAS/FIGNL1/NDUFA7/COX7B	162
BP	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	55/7096	95/18670	6.425e-05	0.001519	0.001132	PSMB9/CUL1/FBXO6/PSMB8/FBXW7/PSMA5/PSMD11/SKP2/PSME1/FBXL5/PSMB10/PSMA1/PSMA4/FBXL20/PSMB1/PSMC4/FBXO38/PSMD13/FBXL18/PSMB3/FBXL4/FBXL3/PSMB5/RNF7/PSMD6/PSMC3/PSME3/PSMC6/FBXO4/FBXL6/FBXL2/PSMC1/CUL2/PSMD8/PSMA2/FBXL7/FBXO27/FBXO44/CUL4B/LRRC29/PSMC5/FBXL17/PSMC2/PSMB2/PSMD4/FBXL14/RBX1/PSMD1/PSMB4/FBXL12/PSMD9/KIF14/PSMD3/FBXL16/CCNF	55
BP	GO:0010948	negative regulation of cell cycle process	173/7096	361/18670	6.699e-05	0.00157	0.001171	KLF4/TPRA1/DUSP1/CDKN2D/CDKN1A/MAD2L2/GPNMB/PSMB9/CUL1/BCL6/PSMB8/MIF/DYNC1LI1/ZNF655/FBXW7/RGCC/HUS1B/ATF5/CBX5/PSMA5/SLFN11/PSMD11/EZH2/SPDL1/RYBP/PKD2/GIGYF2/PSME1/BTG2/KAT2B/GPR132/ZNF268/TRIM37/CDK4/RAD1/TAOK3/ZNF830/PSMB10/PSMA1/PSMA4/PCGF2/E2F6/UIMC1/TFAP4/NAA10/SYF2/FZD9/SETMAR/RBBP7/CDKN2B/PLK2/SFN/KLHL22/NPM1/CDK5RAP2/PSMB1/PSMC4/TOM1L1/DONSON/MGA/PML/RBBP4/PSMD13/CDK2AP2/HMGN5/PSMB3/TOM1L2/BMP7/CCND1/HLA-G/CDK9/ESPL1/ZNF207/LCMT1/PSMB5/PSMD6/ATM/TNKS1BP1/BUB3/MUC1/PSMC3/CTDSPL/PLK3/PSME3/NACC2/RAD17/NDC80/BCL2/PCNA/BMP4/BAX/PSMC6/CHMP2A/CBX3/CRADD/CASP2/CTDSP1/RFWD3/CDKN1B/CDKN2C/CCNK/CNOT4/FHL1/PLAGL1/GEN1/ARID3A/ZW10/RRM2/FOXO4/EVI2B/TICRR/BTN2A2/RING1/MIIP/DTL/CALR/MOS/E2F4/BRCA1/CNOT7/GML/CTDSP2/EPC1/KAT2A/MDM2/PHC1/PSMC1/SMC3/ZFP36L2/CLSPN/WEE1/RBL2/MTBP/DCUN1D3/PSMD8/PSMA2/FBXL7/TOPBP1/CDC20/PCID2/HSP90AB1/RB1/C10orf99/PPP2R5B/MEN1/CNOT10/CARM1/JADE1/PSMC5/YAF2/PSMC2/PSMB2/PSMD4/AURKAIP1/TRIAP1/AURKA/BRSK1/CDC73/RBX1/SOX4/BRCC3/IK/PSMD1/PRMT1/UXT/PSMB4/ZFYVE19/PSMD9/PSMD3/HORMAD1/E2F8/SUSD2/CCNF	173
BP	GO:0046631	alpha-beta T cell activation	75/7096	138/18670	6.71e-05	0.00157	0.001171	PNP/CCR2/PTGER4/NFKBIZ/ANXA1/ELF4/CD55/IRF1/ARG2/STAT6/STAT3/TNFRSF14/BCL6/NLRP3/SH3RF1/SMAD7/LY9/IL4R/CBFB/PTPRC/IL15/HFE/BATF/FUT7/LILRB1/IL18R1/SOCS5/TCIRG1/SEMA4A/ZBTB7B/HLA-E/RELB/ABL1/RSAD2/NFKBID/AGER/RASAL3/HMGB1/ITK/IL6/BCL2/GPR18/IL12RB1/CD300A/CD274/LGALS9/EBI3/ADA/HLX/IL18/AP3B1/BCL11B/TNFSF4/SOCS1/RORA/IFNG/ATP7A/IL12B/PRKCZ/CD80/TBX21/MTOR/PRKCQ/FOXP1/RHOA/GPR183/CD83/CCL19/MALT1/ZBTB16/TNFSF8/CD3E/TWSG1/CDH26/IL23A	75
BP	GO:0009161	ribonucleoside monophosphate metabolic process	170/7096	354/18670	6.715e-05	0.00157	0.001171	IGF1/CBFA2T3/HK3/UPP1/LDHA/PINK1/FBP1/PGK1/VPS9D1/STAT3/PFKFB3/NUP62/NUP160/PFKM/UQCRC2/PFKP/GAPDH/SLC25A25/NUP214/SLC2A6/P2RX7/UQCR11/NDUFA8/NUPR1/AK3/PGAM1/AK2/PKM/GALK1/EIF6/TPI1/MPP1/ZBTB7A/NDUFC1/TGFB1/GMPS/NUP85/CLPX/HIF1A/ISCU/SEH1L/NDUFB11/ADK/INSR/ALDOC/NDUFS3/GUK1/PAICS/NUP43/IMPDH1/NDUFA3/NMNAT1/ATP6V1A/ENO1/DNAJC30/ALDOA/UQCC2/NDUFA11/PARG/CMPK1/POM121/RFK/OGDH/CHCHD10/UQCR10/NUDT9/COX7C/GPI/ATP6V1B2/PFKFB4/PPARGC1A/FLCN/COX7A2L/DHTKD1/NDUFA4/SLC25A12/SHMT2/LDHC/PRKAG2/MYOG/NCOR1/COX4I2/NDUFA1/NUDT3/PFKFB1/GMPR2/ATIC/NUP88/HDAC4/ATP1B1/NUDT5/TEFM/COQ9/NUP107/PRPS1/PPAT/COA6/COX15/NDUFA10/FOXK2/NDUFB1/DDIT4/NDUFB5/UQCRQ/AMPD2/PGK2/PFKFB2/ADA/ARNT/DNM1L/NDUFS1/UCK1/SLC25A33/PPARA/NUP93/SLC25A13/NDUFB8/PRKAA1/PSEN1/DNAJC15/NUP205/ENO2/PID1/SURF1/NDUFB6/BAD/SLC4A1/PRPS1L1/TREM2/CAD/NUP50/IFNG/PRKAG1/OGT/ATP7A/PRPS2/NDUFB3/SDHA/ESRRB/ZBTB20/VCP/NDUFS7/ADPGK/NDUFV2/ND4/SDHD/RHOA/UCKL1/TAZ/APP/SNCA/UQCRB/UPP2/ATP6V1B1/AMPD3/ABCD1/NDUFB2/SDHAF2/LHPP/MYH3/COX6C/ATP1A2/PFKL/CTNS/NDUFS2/POM121C/AAAS/FIGNL1/NDUFA7/COX7B	170
BP	GO:0032680	regulation of tumor necrosis factor production	85/7096	160/18670	6.818e-05	0.001589	0.001184	IGF1/NOD2/CCR2/TLR1/CX3CR1/TLR2/PTPN6/IL27RA/ACP5/CLEC7A/ZFP36/WNT5A/AZU1/ARG2/GPNMB/SYT11/LILRA5/TNFAIP3/MIF/CD2/LY96/LILRA2/JAK2/GSTP1/PTPRC/IRAK3/LILRB1/SLAMF1/TICAM1/AXL/PTAFR/HSPB1/CD36/FRMD8/LEP/TLR4/DDX58/PTPN22/HLA-E/CACTIN/AGER/RASGRP1/DHX9/ARHGEF2/UBE2J1/HMGB1/CLU/TYROBP/MAVS/LRRK2/DICER1/HDAC2/AKAP8/IFIH1/MAPKAPK2/CD47/GPR18/LGALS9/CYBA/CYBB/FZD5/IFNGR1/FADD/PSEN1/TREM2/HAVCR2/IFNG/CD34/TLR3/LBP/IL12B/ZBTB20/CD33/FOXP1/C5AR2/APP/CX3CL1/CCL19/TIRAP/HMGB4/NR1H4/NLRC3/IL23A/GHRL/PTPRJ	85
BP	GO:0000209	protein polyubiquitination	151/7096	310/18670	7.011e-05	0.001628	0.001213	NOD2/TRIM32/LONRF1/WWP1/BARD1/PSMB9/CUL1/RNF41/ZFP91/TNFAIP3/FBXO6/PSMB8/BIRC2/SIAH1/FBXW7/FBXO30/RNF111/CBFB/UBE2N/PSMA5/PSMD11/SKP2/UBE2Q2/PSME1/PLAA/RNF19B/FBXL5/FBXW2/TMEM129/UBE4B/NMI/UBE3A/UBE2K/UBE2S/PSMB10/PSMA1/PSMA4/UBE2D3/RBBP6/IRF2BP1/TRAF6/RNF217/FBXL20/PTPN22/UNKL/UBE2D2/IFI27/ANKIB1/PSMB1/PSMC4/FBXO38/UBR5/UBE2W/UBE2E1/RNF146/PSMD13/UBE2A/FBXL18/PSMB3/FBXL4/RBCK1/UBE2G2/NHLRC3/RNF213/CDC23/RNF115/FBXL3/PSMB5/PSMD6/HERC6/ANAPC5/DTX3L/PSMC3/ARIH2/PSME3/UBE2E2/TRIM21/BCL2/NEDD4/PSMC6/UBE2D4/ANAPC7/RNF126/UBC/SPSB1/RFFL/UBE2C/STUB1/DTL/RNF20/HACE1/FBXO4/NFE2L1/CDC26/BRCA1/WWP2/TRAF2/BFAR/HERC5/DDB2/PSMC1/ANAPC4/SHPRH/PSMD8/PSMA2/FBXL7/ZNRF1/CDC27/FBXO27/RNF4/ZSWIM2/FBXO44/RNF5/PRPF19/THOP1/PSMC5/FOXF2/UBE2G1/TRIM6/FBXL17/PSMC2/PSMB2/PSMD4/RUSC1/FBXL14/TOPORS/FBXL19/ANAPC11/RNF167/RNF216/RBX1/KLHL42/RLIM/ANAPC13/XIAP/PSMD1/TRIM58/CHFR/UBE2B/PSMB4/PELI2/FBXL12/PSMD9/PSMD3/UBE3B/FBXL16/SIAH2/ZNRF2/CCNF/SASH1/ERCC8	151
BP	GO:1903311	regulation of mRNA metabolic process	157/7096	324/18670	7.111e-05	0.001645	0.001226	MYD88/CELF6/TRA2B/ZFP36/SLC11A1/NSRP1/JMJD6/SRSF5/BARD1/VIM/PSMB9/TOB1/PSMB8/ZC3H14/NUP214/AGO2/PSMA5/PSMD11/PAF1/KHDRBS1/YTHDF3/MOV10/TNPO1/HNRNPR/METTL14/GIGYF2/SECISBP2/PSME1/BTG2/DAZAP1/RNPS1/THRAP3/PAIP1/RBM7/ZBTB7A/RBM42/FASTKD1/SRSF10/PSMB10/HSPB1/PSMA1/PSMA4/PRKCD/METTL3/HNRNPK/MBNL1/YTHDC1/RBM4/SAMD4B/RBM4B/HNRNPA1/NPM1/HNRNPA2B1/PSMB1/RBM8A/PSMC4/DHX9/SRPK2/DCP2/SFSWAP/SRSF3/PSMD13/ZC3H12D/SLTM/PSMB3/MBNL3/CDK9/RBMXL1/PAPOLA/PUM2/PSMB5/PSMD6/RBM3/SNRPA/ZC3HAV1/PSMC3/SCGB1A1/CWC22/FTO/HNRNPC/PSME3/GTPBP1/XRN1/MAPKAPK2/EXOSC2/PSMC6/HNRNPA0/SRSF6/PRDX6/SREK1/CPEB1/SRSF7/RNASEL/CSDC2/UBC/TNRC6B/SF3B4/SRPK1/EXOSC7/TNRC6A/HNRNPD/CPEB3/YBX3/HNRNPM/LEO1/RNF20/TBRG4/AHCYL1/C1QBP/CNOT7/FMR1/PSMC1/ZFP36L2/EIF4G1/CELF2/SRSF4/PSMD8/PSMA2/EXOSC9/ZC3H10/VIP/RBM25/EXOSC3/PCID2/SET/PRPF19/PSMC5/CELF3/PSMC2/PSMB2/PSMD4/HMX2/MTOR/CCNT1/SRRM4/CDC73/SAMD4A/EXOSC6/SAP18/PNPT1/TIRAP/CPSF7/EXOSC8/PSMD1/ROCK2/PSMB4/NBAS/SYNCRIP/BOLL/TARDBP/PRKCA/PSMD9/PSMD3/SON/EXOSC5/PLEKHN1/UPF1	157
BP	GO:0009132	nucleoside diphosphate metabolic process	84/7096	158/18670	7.246e-05	0.001667	0.001243	IGF1/CBFA2T3/HK3/LDHA/FBP1/PGK1/STAT3/PFKFB3/NUP62/NUP160/PFKM/PFKP/GAPDH/NUP214/SLC2A6/P2RX7/NUPR1/AK3/PGAM1/AK2/PKM/GALK1/EIF6/TPI1/MPP1/ZBTB7A/NUP85/HIF1A/SEH1L/INSR/ALDOC/GUK1/NUP43/ENO1/ALDOA/AK8/CMPK1/POM121/OGDH/CMPK2/NUDT9/GPI/PFKFB4/PPARGC1A/DHTKD1/NME3/SLC25A12/NME4/PRKAG2/MYOG/NCOR1/PFKFB1/NUP88/HDAC4/NME1/NUDT5/NUP107/FOXK2/DDIT4/PGK2/PFKFB2/ARNT/NUDT7/PPARA/NUP93/PRKAA1/PSEN1/NUP205/ENO2/BAD/SLC4A1/NUP50/IFNG/PRKAG1/OGT/ESRRB/ZBTB20/ADPGK/APP/AMPD3/NUDT16/PFKL/POM121C/AAAS	84
BP	GO:0002262	myeloid cell homeostasis	79/7096	147/18670	7.257e-05	0.001667	0.001243	EPAS1/CCR2/KLF2/ANXA1/SPI1/LYN/ZFP36/SOD1/JMJD6/STAT3/PTPN2/LYAR/THRA/BCL6/SMAD5/KITLG/CEBPG/STAT1/JAK2/LDB1/SLC7A11/HMOX1/TMOD3/HCLS1/AXL/FAM210B/ZBTB7A/HIF1A/PRDX1/SRF/VEGFA/PDE4B/CASP3/TMEM14C/ISG15/HMGB1/RPS24/MFHAS1/KLF13/IL6/ACVR1B/G6PD/TAL1/ETS1/IKZF1/RPS19/KMT2E/BCL2L11/BMP4/BAX/HMGB2/PIK3CD/ID2/SFXN1/INHBA/IREB2/DMTN/ARNT/DYRK3/NFE2L1/CXCR2/ADAM17/JAM3/MERTK/ERCC2/SLC4A1/EPB42/BAP1/RB1/INHA/AMPD3/SLC25A38/ADAR/BAK1/TRIM58/PRMT1/DNASE2/FOXO3/PIK3CB	79
BP	GO:0006165	nucleoside diphosphate phosphorylation	73/7096	134/18670	7.523e-05	0.001716	0.001279	IGF1/CBFA2T3/HK3/LDHA/FBP1/PGK1/STAT3/PFKFB3/NUP62/NUP160/PFKM/PFKP/GAPDH/NUP214/SLC2A6/P2RX7/NUPR1/PGAM1/PKM/GALK1/EIF6/TPI1/ZBTB7A/NUP85/HIF1A/SEH1L/INSR/ALDOC/NUP43/ENO1/ALDOA/AK8/CMPK1/POM121/OGDH/CMPK2/GPI/PFKFB4/PPARGC1A/DHTKD1/NME3/NME4/PRKAG2/MYOG/NCOR1/PFKFB1/NUP88/HDAC4/NME1/NUP107/FOXK2/DDIT4/PGK2/PFKFB2/ARNT/PPARA/NUP93/PRKAA1/PSEN1/NUP205/ENO2/SLC4A1/NUP50/IFNG/PRKAG1/OGT/ESRRB/ZBTB20/ADPGK/APP/PFKL/POM121C/AAAS	73
BP	GO:0050856	regulation of T cell receptor signaling pathway	27/7096	39/18670	7.524e-05	0.001716	0.001279	EZR/KCNN4/PTPN6/BCL10/GBP1/PTPN2/DUSP3/RELA/CD226/LILRB4/PTPN22/TESPA1/RAB29/ELF1/LCK/CYLD/TRAT1/PRKD2/CD300A/BTN2A2/ADA/MALT1/CCR7/CACNA1F/UBASH3A/PTPRJ/PHPT1	27
BP	GO:0033209	tumor necrosis factor-mediated signaling pathway	88/7096	167/18670	7.56e-05	0.001718	0.001281	TRIM32/PTPN2/PSMB9/TNFRSF14/TNFAIP3/CD40/PSMB8/BIRC2/ACTN4/STAT1/JAK2/GSTP1/PSMA5/TNF/PSMD11/NFKBIA/PSME1/AIM2/RELA/PSMB10/PTK2B/TXNDC17/PSMA1/TNFSF13B/PSMA4/SPPL2A/IKBKG/TRAF3/CARD14/TNFRSF12A/CASP8/PSMB1/PSMC4/PSMD13/SPATA2/TNFRSF11A/TRADD/PSMB3/TNFRSF18/RBCK1/CYLD/PSMB5/PSMD6/EDA/MIR34A/PSMC3/SPHK1/PSME3/EDAR/PSMC6/BIRC3/CASP1/RFFL/KRT8/HIPK1/TRAF1/PIAS3/ADAM17/TRAF2/CASP4/TNFRSF13B/TNFSF4/CPNE1/TAX1BP1/APOA1/PSMC1/TNFRSF4/PSMD8/PSMA2/ST18/CLDN18/TNFSF18/TNFRSF25/TNFRSF13C/PSMC5/PSMC2/PSMB2/PSMD4/LIMS1/CLIP3/CHUK/PSMD1/TNFSF8/PSMB4/NR1H4/PSMD9/PSMD3/FOXO3	88
BP	GO:0009162	deoxyribonucleoside monophosphate metabolic process	12/7096	13/18670	7.629e-05	0.001728	0.001288	DGUOK/CDADC1/GUK1/TK1/DNPH1/TYMS/DCK/SHMT1/TK2/DCTD/NT5M/DUT	12
BP	GO:0002367	cytokine production involved in immune response	58/7096	102/18670	8.297e-05	0.001872	0.001396	NOD2/CCR2/TLR2/BCL10/CD55/SLC11A1/DDX21/WNT5A/TNFRSF14/BCL6/NLRP3/SMAD7/MIF/HFE/TNF/IRAK3/CD74/HMOX1/GPRC5B/LILRB1/TICAM1/DENND1B/CD226/TGFB1/IL18R1/FFAR2/CD36/HLA-F/TRAF6/CLC/TLR4/DDX58/HLA-E/RSAD2/IL1B/SIRT1/TRPM4/IL1R1/HLA-G/MAVS/IL6/CD96/DDX1/FZD5/KIR2DL4/IL18/TRAF2/TNFSF4/APOA1/TGFB3/NR4A3/TLR3/IL12B/TRIM6/PRKCZ/TBX21/IL18RAP/MALT1	58
BP	GO:0046486	glycerolipid metabolic process	195/7096	414/18670	8.423e-05	0.001894	0.001412	FPR2/HTR2B/LPCAT2/SLC27A1/CDS1/SLC22A4/PLA2G12A/SOCS3/HADHB/FABP4/ENPP2/CHPT1/DGKA/CAPN2/GPAM/ABHD4/PLSCR1/PLEKHA1/MBOAT7/GDE1/MTMR12/ABHD6/PANK2/FBXW7/ABHD12/SIK1/GPCPD1/PIGV/ATG14/CDS2/PIGP/APOC1/GK/SCARB1/PTDSS2/PLA2G7/MGLL/MBOAT1/IMPAD1/PTPMT1/PLBD1/CISH/PIGK/CETP/INPP1/APOE/LPGAT1/PIK3R3/PTPN13/PNPLA6/PLD1/PNPLA3/SACM1L/CSNK2A2/PIGN/DGKD/STARD10/IP6K1/SOCS5/PCK2/SYNJ1/NR1H2/PITPNM1/PLA1A/NAPEPLD/DDHD1/TTC7A/SOCS6/SERINC1/ACSL4/FIG4/CAT/FAM126A/AGPAT3/PAFAH1B1/PLA2G15/PLCG2/LDLR/PLB1/LMF1/PIK3R6/CSNK2B/PIGF/SYNJ2/STARD7/APOBR/SIRT1/CDIPT/DGAT2/FABP3/PIGB/DPM1/OCRL/SOCS7/PDGFB/ABHD3/AGPAT4/GPAA1/SH3YL1/RAB38/ALDH5A1/GNB3/APOA5/PNPLA8/ATM/ARF1/CRLS1/PIGM/DAGLB/MFSD2A/PLA2G3/PLEKHA8/MBOAT2/SBF1/LCAT/SERINC3/GK5/MTMR4/TMEM86B/MPPE1/INPP5K/IMPA2/MTMR6/PIK3CD/PRDX6/NR1H3/PNPLA5/PI4K2A/RAB5A/PIGQ/ACP6/MTMR2/CPT1A/INPP5F/PLEK/PDGFA/FAR1/PIGO/HADHA/CHKA/PIGH/SERPINA12/INSIG1/PLCB1/FABP5/CAV3/AGK/AGPAT5/DBI/PLD2/PLCD4/CPNE1/DPM3/MTMR3/PLEKHA3/APOA1/SOCS1/PLA2G6/DGKG/PIGT/GNPAT/CPNE3/MTMR9/SLC44A2/PIK3CG/SLA2/GPX1/SERAC1/CSF1R/AGPAT1/PIP5K1B/CHAT/TAZ/VAC14/ABHD16A/LPCAT1/CHKB/PGS1/AGPAT2/SOCS2/SERINC2/PGAP3/INPPL1/THRSP/NR1H4/ARF3/EFR3A/PGAP1/G6PC/PNPLA4/INPP5A/PIK3CB/IMPA1/PI4KB/LPCAT3	195
BP	GO:1901136	carbohydrate derivative catabolic process	99/7096	192/18670	8.515e-05	0.001904	0.001419	FUCA1/TYMP/PNP/HEXB/UPP1/VCAN/MANBA/NAGLU/GM2A/CHP1/GNPDA1/FBXO6/NPL/AHCY/IDS/ACOT7/CD44/PSAP/SLC9A1/HEXA/CST3/EDEM1/HDDC3/TGFB1/ARSB/NEIL2/SGSH/UNG/NUDT1/GALC/NAGK/NT5C/PRKCD/HYAL2/CDADC1/GNS/RENBP/PDE4B/DPYD/HINT1/CSPG4/SAMHD1/MMP12/NUDT9/APOBEC3G/GLA/IDUA/ADAMTS12/EDEM2/TDG/CTBS/APOBEC3C/MLYCD/GUSB/APOBEC2/PGM2/HPSE/NUDT3/STT3B/PDE7A/DERA/NAGA/MAN1B1/GALT/HYAL3/PGLYRP4/BCAN/NGLY1/ADA/CEMIP/NUDT7/APOBEC3B/GPC2/FUCA2/STAB2/NEU1/FBXO27/FBXO44/CDA/DCTPP1/GPC4/LYVE1/SDC3/PDE8A/NT5C3A/ENPP4/NT5M/UPP2/AMPD3/ABCD1/ADAL/DUT/EDEM3/ABHD10/NUDT16/MBD4/PDE8B/ADAMTS9/SMUG1	99
BP	GO:0006446	regulation of translational initiation	47/7096	79/18670	8.554e-05	0.001904	0.001419	EIF1/PPP1R15A/ALKBH1/BANK1/AGO2/TNF/EIF1B/KHDRBS1/YTHDF3/ATF4/PAIP1/HSPB1/METTL3/MTIF2/RBM4/EIF2B5/HABP4/NCK1/EIF4B/NPM1/CCL5/PPP1R15B/EIF4H/EIF2S1/EIF4EBP2/EIF4G2/DDX3X/RXRA/EIF4G3/DDX1/EIF3B/EIF5/POLR2D/IMPACT/PPP1CA/EIF2AK2/FMR1/KLHL25/EIF2AK1/EIF4G1/EIF2B1/RPS6KB2/EIF2AK4/MTOR/EIF2B2/BOLL/PAIP2B	47
BP	GO:0032640	tumor necrosis factor production	86/7096	163/18670	8.555e-05	0.001904	0.001419	IGF1/NOD2/CCR2/TLR1/CX3CR1/TLR2/PTPN6/IL27RA/ACP5/CLEC7A/ZFP36/WNT5A/AZU1/ARG2/GPNMB/SYT11/LILRA5/TNFAIP3/MIF/CD2/LY96/LILRA2/JAK2/GSTP1/PTPRC/IRAK3/LILRB1/SLAMF1/TICAM1/AXL/PTAFR/HSPB1/CD36/FRMD8/LEP/TLR4/DDX58/PTPN22/HLA-E/CACTIN/AGER/RASGRP1/DHX9/ARHGEF2/UBE2J1/HMGB1/CLU/TYROBP/MAVS/LRRK2/DICER1/AZI2/HDAC2/AKAP8/IFIH1/MAPKAPK2/CD47/GPR18/LGALS9/CYBA/CYBB/FZD5/IFNGR1/FADD/PSEN1/TREM2/HAVCR2/IFNG/CD34/TLR3/LBP/IL12B/ZBTB20/CD33/FOXP1/C5AR2/APP/CX3CL1/CCL19/TIRAP/HMGB4/NR1H4/NLRC3/IL23A/GHRL/PTPRJ	86
BP	GO:0042088	T-helper 1 type immune response	29/7096	43/18670	8.62e-05	0.001908	0.001423	CCR2/IL27RA/ANXA1/SLC11A1/STAT6/IL4R/IL18R1/SOCS5/IL18BP/TRAF6/SEMA4A/TLR4/HRAS/RELB/IL1B/HMGB1/IL1R1/IL12RB1/EBI3/HLX/IL18/TNFSF4/HAVCR2/IL12B/CD80/MTOR/IL18RAP/CCL19/IL23A	29
BP	GO:0071496	cellular response to external stimulus	163/7096	339/18670	8.655e-05	0.001908	0.001423	MYD88/FOS/VDR/FYN/USF2/PTGER4/NAMPT/PDK4/UPP1/CDKN1A/BCL10/ATG7/NR4A2/LYN/IRF1/AIFM1/TSC1/SOD1/ATP1A1/SRD5A1/PIM1/KLF10/PTGS2/TNFRSF10A/PMAIP1/CD40/GAS2L1/SIK1/ATG14/FOLR2/LAMP2/GDAP1/GSTP1/PTPRC/IL15/FAS/P2RX7/HFE/HMOX1/SLC9A1/SKP2/AKR1C3/NFKB1/ATF4/PDK2/AXL/WDR24/HIGD1A/TGFB1/XPR1/NUDT1/MAP1LC3A/SEH1L/TLR5/LEP/BCL11A/SRF/BAIAP2/ITGA4/TLR4/HABP4/HSPA5/HNRNPA1/CDKN2B/PPM1D/GCLC/CASP8/IL1B/AIF1/SIK2/RRAGD/CASP5/P2RY12/WIPI1/NPRL3/SIRT1/TRPM4/RAC1/EIF2S1/KPTN/LRRK2/MAP1LC3C/NMRAL1/CNN2/FNIP1/ZFYVE1/TRIM24/MYBBP1A/MAPK8/ADORA2B/BCL2/CRADD/HDAC4/CASP2/ASNS/CASP1/ITGA2/WDR45B/CTSV/CYBA/CYBB/TNRC6A/SREBF2/MAP3K5/RRAGA/DNM1L/NFE2L2/TNFRSF10B/IMPACT/EIF2AK2/ULK1/EGFR/DSC2/ITFG2/FADD/AMIGO1/SESN1/HSP90B1/AQP3/PRKAA1/DNAJC15/TLR8/MDM2/MAPK1/MTMR3/P2RY4/SH3GLB1/CYP27B1/NPRL2/MAP2K4/BAD/EIF4G1/DAP/TBL2/FOSL1/DAPL1/MAP3K1/GABARAPL1/CLEC16A/TLR3/CACNB3/WNT2B/EIF2AK4/DCTPP1/ASGR1/CADPS2/MTOR/PICK1/DAG1/DEPDC5/ENG/CIB2/SSH1/BAK1/ATP1A2/FGF23/GJA1/NR1H4/SESN2/UCN3/P2RY1/ALB/BMPR2	163
BP	GO:0070585	protein localization to mitochondrion	76/7096	141/18670	8.664e-05	0.001908	0.001423	BMF/RAC2/PINK1/TIMM23B/IMMP1L/UQCRC2/HPS4/PMAIP1/SIRT4/FBXW7/YWHAH/MIPEP/GDAP1/CSNK2A2/FIS1/UBE2D3/HTRA2/DNAJC19/SFN/CASP8/TIMM8B/TIMM17A/ATG13/TIMM21/GRPEL1/LRRK2/RHOU/PDCD5/TIMM10B/IMMP2L/GRPEL2/ARIH2/BCL2L11/MAPK8/ABLIM3/BCL2/BAX/TOMM22/MICALL2/GZMB/TOMM40L/OXA1L/UBL4B/TOMM40/LMAN1/YWHAQ/SREBF2/FZD5/DNM1L/TOMM20/HSPA1L/TIMM22/PITRM1/AGK/HSPA4/PRKAA1/DNAJC15/PARL/SH3GLB1/YWHAE/BAD/UBL5/PPP1R13B/BAP1/MOAP1/DNAJA1/TOMM5/PMPCB/YWHAG/TIMM50/MTCH2/TOMM34/MGARP/TIMM44/TIMM9/AIP	76
BP	GO:0010565	regulation of cellular ketone metabolic process	94/7096	181/18670	8.993e-05	0.001974	0.001472	NQO1/ATP2B4/PDK4/ANXA1/APPL2/STARD4/OAZ2/PTGS2/PSMB9/ADIPOR1/PSMB8/SIRT4/PANK2/RDH10/SLC45A3/APOC1/EGR1/PSMA5/PSMD11/SLC7A11/CD74/ELOVL5/AKR1C3/PSME1/LPGAT1/PDK2/EIF6/SLC7A7/PSMB10/PSMA1/PSMA4/NR1H2/ERLIN1/OAZ3/BMP2/PSMB1/GSTZ1/IL1B/ODC1/PSMC4/ERLIN2/ACACB/PSMD13/COQ3/PSMB3/SIRT1/DGAT2/FABP3/IRS2/PPARGC1A/MLYCD/APOA5/PSMB5/PSMD6/PSMC3/PRKAG2/BMP5/PSME3/SIRT5/SCAP/PSMC6/NR1H3/BHMT/PDK1/TYSND1/CPT1A/AZIN1/ACADVL/NFE2L1/INSIG1/PDP2/FABP5/BRCA1/PPARA/ADIPOR2/PSMC1/PSMD8/PSMA2/NR4A3/PDP1/PSMC5/PSMC2/PSMB2/PSMD4/MTOR/SNCA/ABCD1/ATCAY/PDPR/PSMD1/PSMB4/NR1H4/PSMD9/PSMD3	94
BP	GO:0001782	B cell homeostasis	22/7096	30/18670	9.067e-05	0.001983	0.001478	SH2B2/BCL10/LYN/TNFAIP3/MIF/DOCK10/CD74/HIF1A/TNFSF13B/CASP3/ABL1/BCL2L11/BCL2/BAX/PPP2R3C/ADA/DOCK11/TNFRSF13B/GAPT/TNFRSF13C/BAK1/MEF2C	22
BP	GO:0006626	protein targeting to mitochondrion	56/7096	98/18670	9.094e-05	0.001983	0.001478	RAC2/PINK1/TIMM23B/IMMP1L/UQCRC2/HPS4/SIRT4/FBXW7/MIPEP/GDAP1/CSNK2A2/FIS1/UBE2D3/HTRA2/DNAJC19/TIMM8B/TIMM17A/ATG13/TIMM21/GRPEL1/LRRK2/RHOU/PDCD5/TIMM10B/IMMP2L/GRPEL2/ARIH2/ABLIM3/TOMM22/MICALL2/TOMM40L/UBL4B/TOMM40/LMAN1/SREBF2/FZD5/TOMM20/HSPA1L/TIMM22/PITRM1/AGK/HSPA4/PRKAA1/DNAJC15/PARL/SH3GLB1/UBL5/BAP1/TOMM5/PMPCB/TIMM50/TOMM34/MGARP/TIMM44/TIMM9/AIP	56
BP	GO:0006839	mitochondrial transport	127/7096	256/18670	9.336e-05	0.002029	0.001512	BMF/RAC2/SFXN3/PINK1/SLC35F6/BLOC1S2/TIMM23B/SLC25A37/IMMP1L/STAT3/UQCRC2/HPS4/PMAIP1/SIRT4/FBXW7/YWHAH/MIPEP/SLC25A20/GDAP1/SLC9A1/SLC25A28/TMEM14A/GSK3B/ALKBH7/CSNK2A2/CPT2/MRS2/FIS1/UBE2D3/MCU/MPV17L/HTRA2/FZD9/DNAJC19/SFN/DNAJC30/CASP8/TIMM8B/UCP2/TMEM14C/TIMM17A/RHOT2/SLC25A10/MPC2/ACACB/ATG13/CHCHD10/ABCB10/TIMM21/GRPEL1/SLC25A15/AFG3L2/SLC25A5/LRRK2/RHOU/PDCD5/PSEN2/TIMM10B/IMMP2L/SLC25A12/GRPEL2/ARIH2/TST/PRKAG2/BCL2L11/MAPK8/ABLIM3/TMEM102/BCL2/BAX/TOMM22/MICALL2/GZMB/TOMM40L/THEM4/UBL4B/TOMM40/CPT1A/LMAN1/MICU1/YWHAQ/SREBF2/FZD5/CAMK2A/UCP1/TOMM20/HSPA1L/TIMM22/MUL1/SLC25A33/PITRM1/SLC25A13/AGK/ACAA2/LETM1/HSPA4/PRKAA1/PSEN1/DNAJC15/PARL/SH3GLB1/YWHAE/SLC25A16/BAD/UBL5/PPP1R13B/NAIF1/BAP1/MOAP1/SLC25A24/TOMM5/PMPCB/CNP/YWHAG/SLC25A22/SLC25A32/PNPT1/SLC25A38/TIMM50/BAK1/THRSP/TOMM34/MGARP/TIMM44/MICU2/TIMM9/AIP	127
BP	GO:2001169	regulation of ATP biosynthetic process	55/7096	96/18670	9.511e-05	0.00206	0.001536	IGF1/CBFA2T3/PINK1/FBP1/STAT3/PFKFB3/NUP62/NUP160/NUP214/SLC2A6/P2RX7/NUPR1/PGAM1/EIF6/ZBTB7A/NUP85/HIF1A/SEH1L/INSR/NUP43/ENO1/DNAJC30/POM121/PFKFB4/PPARGC1A/FLCN/SLC25A12/PRKAG2/MYOG/NCOR1/PFKFB1/NUP88/HDAC4/NUP107/DDIT4/PFKFB2/ARNT/PPARA/NUP93/PRKAA1/PSEN1/NUP205/PID1/TREM2/NUP50/IFNG/PRKAG1/OGT/ESRRB/ZBTB20/VCP/TAZ/APP/POM121C/AAAS	55
BP	GO:0001933	negative regulation of protein phosphorylation	201/7096	429/18670	9.651e-05	0.002076	0.001547	KLF4/MYADM/ITPRIP/EZR/PTPN6/DUSP1/PRKAR2B/CDKN2D/CDKN1A/SOCS3/DUSP6/LYN/PINK1/PPP2CA/FABP4/DUSP5/CSK/GBP1/C9orf72/PTPN2/NUP62/CHP1/SMAD7/DUSP10/ZBED3/TNFAIP3/CIB1/RGS2/ATG14/UCHL1/MYC/DUSP7/NLRP12/RNF149/GSTP1/PTPRC/P2RX7/IRAK3/EPHB2/PEBP1/TESC/APOE/HMGCR/MICAL1/KAT2B/PTPN13/DUSP3/LRP5/PBLD/HEXIM1/NDRG2/LDLRAD4/TGFB1/TAOK3/GADD45B/HGF/ARRB1/CBLB/GNAQ/DUSP18/SOCS5/HSPB1/ZFYVE28/RANBP9/HEG1/PRKCD/LATS1/PKIB/GMFG/ZGPAT/HYAL2/MBIP/DUSP2/TFAP4/TLR4/PTPN22/ADARB1/CEBPA/DUS2/IGF1R/NCK1/CDKN2B/CASP3/CACTIN/SFN/NPM1/ABL1/PAFAH1B1/PAK2/IL1B/PMEPA1/DTNBP1/MVP/PTK6/CDKN1C/PAQR3/SEMA4D/DMD/SH3BP5L/PPM1F/SIRT1/HEXIM2/PPP1R15B/BMP7/DUSP19/CYLD/LRRK2/SMYD3/PPARGC1A/SPINK1/FLCN/SNX6/DUSP14/RGS3/DUSP4/PRKAG2/NCOR1/CTDSPL/GFRA2/ASH1L/STRAP/TARBP2/BMP4/TNIP1/BAX/INPP5K/RGS14/CTDSP1/CDKN1B/CDKN2C/TSG101/TRIB2/CHRNA10/ZMYND11/DNAJC10/AKT1S1/CD300A/GSKIP/INPP5F/LAX1/DDIT4/RABGEF1/BTN2A2/AMBP/DMTN/SPRY1/CORO1C/VPS25/PWP1/IMPACT/SPRED1/CTDSP2/CAV3/SLIT2/CHORDC1/SPRY2/DVL1/DEPTOR/PSEN1/IPO7/PID1/SMCR8/SOCS1/EIF4G1/PPEF2/IGBP1/IFNG/HIPK3/FGFR1OP/LATS2/DNAJA1/PIN1/BDKRB1/SMPD1/RB1/MEN1/YWHAG/TRAF3IP1/PKIA/PRKCZ/PRDM15/MTOR/GPS1/DAG1/SNCA/ITGB1BP1/ENG/PDCD4/ADAR/BAK1/AIDA/UBE2B/GREM1/NNT/TARDBP/CEP85/WNK2/CD109/TAF7/PTPRJ/MIR146A	201
BP	GO:0045862	positive regulation of proteolysis	173/7096	363/18670	9.662e-05	0.002076	0.001547	S100A9/S100A8/FN1/CBFA2T3/FYN/TRIM32/MAPK12/CLEC7A/TMTC3/GRN/BCL10/LYN/PINK1/AIFM1/GRAMD4/STAT3/CTSD/NLRP3/TNFRSF10A/SMAD7/PMAIP1/KEAP1/MBP/DDRGK1/FBXW7/CTSC/LGMN/MYC/NLRP12/RNF139/JAK2/FAS/BCAP31/ADAM8/TNF/NUPR1/IFT57/APOE/GSK3B/PRELID1/PSME1/MAGEF1/AIM2/RNF19B/EDEM1/SGTA/CLPX/FIS1/ARRB1/ZFAND2A/SOCS5/PTK2B/CSNK1D/RNF217/TFAP4/HTRA2/CEBPA/PLK2/CYFIP2/ENO1/TNFSF10/ANKIB1/GCLC/CASP8/IL1B/PSMC4/FURIN/TIMM17A/AGER/ADRM1/DAPK1/PML/CASP5/HMGB1/TRADD/CLU/PPM1F/SIRT1/TTBK1/LCK/SNX33/EDEM2/LRRK2/CR1/EGLN3/SUMO1/PDCD5/DDX3X/PTK2/HSPBP1/MYH9/PRR7/CSNK1A1/CSNK1E/RNFT1/ARIH2/HDAC2/BCL2L11/PLK3/P2RX1/PSME3/DISC1/UBQLN2/MEFV/TNIP1/BAX/CRADD/TRIB2/IST1/CASP1/BBS7/KHDC1/DET1/CLN6/LGALS9/NKD2/ST20/KLHL40/MMP14/MAP3K5/F2R/STUB1/NFE2L2/TNFRSF10B/ATXN3/MUL1/FADD/CAV3/TRAF2/BAG2/CASP4/ADAM9/DVL1/PSEN1/FMR1/MDM2/PSMC1/COL4A3/BAD/TREM2/DAP/NLRP1/CAPN3/ST18/IFNG/OGT/RNF185/NLRP2/WDR35/DIABLO/F3/PSMC2/VCP/AURKAIP1/HPN/RHOA/AURKA/APP/SNCA/SNX9/RBX1/MALT1/BAK1/KCNE2/PICALM/CHFR/ROCK2/AKIRIN2/MIR205/PACSIN3/EFNA3/MAPK9/SOX7	173
BP	GO:0009156	ribonucleoside monophosphate biosynthetic process	101/7096	197/18670	9.68e-05	0.002076	0.001547	IGF1/CBFA2T3/HK3/UPP1/LDHA/PINK1/FBP1/PGK1/VPS9D1/STAT3/PFKFB3/NUP62/NUP160/PFKM/PFKP/GAPDH/NUP214/SLC2A6/P2RX7/NUPR1/AK3/PGAM1/AK2/PKM/GALK1/EIF6/TPI1/ZBTB7A/TGFB1/GMPS/NUP85/HIF1A/SEH1L/ADK/INSR/ALDOC/PAICS/NUP43/IMPDH1/ENO1/DNAJC30/ALDOA/CMPK1/POM121/RFK/OGDH/GPI/PFKFB4/PPARGC1A/FLCN/DHTKD1/SLC25A12/LDHC/PRKAG2/MYOG/NCOR1/PFKFB1/ATIC/NUP88/HDAC4/NUP107/PRPS1/PPAT/FOXK2/DDIT4/AMPD2/PGK2/PFKFB2/ADA/ARNT/UCK1/PPARA/NUP93/SLC25A13/PRKAA1/PSEN1/NUP205/ENO2/PID1/SLC4A1/PRPS1L1/TREM2/CAD/NUP50/IFNG/PRKAG1/OGT/PRPS2/ESRRB/ZBTB20/VCP/ADPGK/UCKL1/TAZ/APP/UPP2/AMPD3/LHPP/PFKL/POM121C/AAAS	101
BP	GO:0072655	establishment of protein localization to mitochondrion	74/7096	137/18670	9.744e-05	0.002082	0.001552	BMF/RAC2/PINK1/TIMM23B/IMMP1L/UQCRC2/HPS4/PMAIP1/SIRT4/FBXW7/YWHAH/MIPEP/GDAP1/CSNK2A2/FIS1/UBE2D3/HTRA2/DNAJC19/SFN/CASP8/TIMM8B/TIMM17A/ATG13/TIMM21/GRPEL1/LRRK2/RHOU/PDCD5/TIMM10B/IMMP2L/GRPEL2/ARIH2/BCL2L11/MAPK8/ABLIM3/BCL2/BAX/TOMM22/MICALL2/GZMB/TOMM40L/OXA1L/UBL4B/TOMM40/LMAN1/YWHAQ/SREBF2/FZD5/TOMM20/HSPA1L/TIMM22/PITRM1/AGK/HSPA4/PRKAA1/DNAJC15/PARL/SH3GLB1/YWHAE/BAD/UBL5/PPP1R13B/BAP1/MOAP1/DNAJA1/TOMM5/PMPCB/YWHAG/TIMM50/TOMM34/MGARP/TIMM44/TIMM9/AIP	74
BP	GO:0006470	protein dephosphorylation	155/7096	321/18670	9.809e-05	0.002089	0.001558	PTPN6/LILRB2/DUSP1/DUSP6/PINK1/PPP2CA/DUSP5/TSC1/CAMTA1/PTPN2/PPP1R15A/MGAT5/EYA3/DUSP10/SSH2/PPM1H/PALD1/DUSP7/JAK2/PTPRC/SHOC2/TNF/PTP4A1/PTPMT1/GSK3B/PTPRO/PPP4C/CABIN1/PTPN13/DUSP3/PPP4R2/TGFB1/PPP3CB/PHACTR2/PPP2R3A/DUSP18/PHACTR1/PPP1R16A/PPP1R26/PPP1R3E/SWAP70/PPP6R1/PRKCD/PTPN7/PPP1R3D/DAPP1/PPP1R14A/DUSP2/ELFN1/PTPN22/PPP1R37/NCK1/RCAN3/PPP1R2/PPM1D/SLC39A10/PPP1R14B/PPA2/PTPN4/SYMPK/PPM1F/PPP1R15B/PPP1R16B/MFHAS1/DUSP19/CTDP1/PPM1M/LCK/CDH5/RPRD1B/DUSP12/PPP2R5C/ANKLE2/RNGTT/DUSP14/DNAJC6/PPP6C/DUSP4/DUSP23/CTDSPL/PPM1N/SBF1/TAB1/BCL2/GNAI2/PPP2R2D/MTMR4/BOD1L1/PPP2R2B/MTMR6/ELFN2/CTDSP1/PPP1R3B/PPM1L/RCAN1/CDC25A/MTMR2/CD300A/PPP4R1/PPP1R36/PTPRN2/PPM1J/PPP1R7/MYOZ1/NSMF/PPP1CC/PPP1CA/PPP2R1B/PDP2/EIF2AK2/PPP1R11/CTDSP2/HSP90B1/MTMR3/DLGAP5/PTPDC1/YWHAE/EYA4/MINPP1/PPEF2/IGBP1/LMTK2/RPAP2/SSH3/PDP1/MASTL/PIN1/B3GAT3/PPP1CB/SMPD1/PPP1R14D/HSP90AB1/PPP2R5B/PHLPP2/PHACTR4/SET/CD33/PTPRH/CDCA2/MTOR/DUSP13/SSH1/PTPRZ1/SDHAF2/TIMM50/LHPP/MYH3/PPM1G/ROCK2/BOD1/CTDSPL2/PPP2R2C/PTPRM/PTPRJ/PHPT1	155
BP	GO:0050854	regulation of antigen receptor-mediated signaling pathway	40/7096	65/18670	0.0001001	0.002126	0.001585	EZR/KCNN4/PTPN6/BCL10/LYN/GBP1/PTPN2/LPXN/CBFB/PTPRC/DUSP3/CD22/RELA/CD226/LILRB4/PTPN22/SLC39A10/TESPA1/RAB29/ELF1/LCK/CYLD/MIR34A/TRAT1/PRKD2/CD300A/GCSAM/BTN2A2/ADA/NFAM1/PLCL2/FOXP1/PAX5/MALT1/CCR7/CMTM3/CACNA1F/UBASH3A/PTPRJ/PHPT1	40
BP	GO:0006968	cellular defense response	34/7096	53/18670	0.0001011	0.002138	0.001594	CLEC5A/CCR2/CX3CR1/LILRB2/BCL10/MNDA/CD300C/LY96/CXCL9/RELA/RAB23/PTK2B/ZNF148/NCF2/TCIRG1/NCF1/TYROBP/HLA-G/ITK/CCR5/CD5L/TRAT1/ADORA2B/CCR6/VEZF1/CCR3/CXCR2/KIR2DL4/PRF1/FOSL1/GNLY/LBP/SH2D1A/NCR1	34
BP	GO:0030888	regulation of B cell proliferation	38/7096	61/18670	0.0001021	0.002154	0.001606	CDKN1A/BST1/LYN/MNDA/BCL6/CD40/MIF/PTPRC/CD74/TNFRSF21/CD320/TICAM1/CD22/TNFSF13B/TLR4/CASP3/SLC39A10/AHR/IL7/TYROBP/IRS2/CTLA4/ATM/BCL2/NFATC2/CLCF1/CD300A/ADA/TFRC/TNFRSF13B/CHRNB2/TNFRSF4/TNFRSF13C/GPR183/IKZF3/TIRAP/ATAD5/MEF2C	38
BP	GO:0033619	membrane protein proteolysis	37/7096	59/18670	0.0001026	0.002155	0.001607	APH1B/LRIG2/TIMP2/ADAM19/P2RX7/ADAM8/TNF/PSENEN/NFKB1/APOE/RELA/TGFB1/TRAF6/SPPL2A/IL1B/FURIN/SNX33/TIMP4/BACE2/PSEN2/MYH9/TIMP1/ADAM17/ADAM9/PSEN1/PARL/ERAP1/IFNG/RET/PRTN3/PRKCQ/MBTPS2/DAG1/SNX9/APH1A/MBTPS1/PACSIN3	37
BP	GO:0043687	post-translational protein modification	172/7096	361/18670	0.0001029	0.002155	0.001607	SERPINA1/EPAS1/KLHL21/FN1/F5/KLHL13/VCAN/SOCS3/ATG7/KBTBD7/PSMB9/CKAP4/CUL1/SPP1/ANKRD9/RAB11A/GOLM1/FBXO6/KEAP1/PSMB8/FBXW7/FBXO30/LAMB2/KLHL41/KBTBD6/SUMF1/SHISA5/FEM1C/PSMA5/PSMD11/CISH/SKP2/IGFBP7/APOE/PSME1/CST3/FBXL5/DCUN1D1/FBXW2/SUMF2/CRTAP/HIF1A/WFS1/SOCS5/PSMB10/IGFBP4/PSMA1/FEM1B/PSMA4/UBXN7/DCAF8/DDB1/FBXL20/SOCS6/QSOX1/LRR1/RBBP7/RCN1/KLHL22/PSMB1/PSMC4/DSCC1/TULP4/ASB7/PSMD13/RAB8A/FBXL18/PSMB3/FBXL4/UBE2F/BTBD6/IL6/FLCN/RAB38/APOL1/FBXL3/APOA5/LCMT1/PSMB5/RNF7/BTBD1/PSMD6/SCG3/KLHL9/PSMC3/PDIA6/KBTBD8/PSME3/STT3B/SPARCL1/BMP4/CAND1/PSMC6/TIMP1/SENP8/RAB5A/LGALS1/VIPAS39/SPSB1/KTN1/ANO8/DTL/ASB8/FBXO4/DCAF13/COMMD1/COPS2/SPSB2/AGBL1/ASB11/HSP90B1/MXRA8/UBE2M/RAB3A/KLHL25/DDB2/APOA1/PSMC1/CUL2/ICMT/DCAF10/DCUN1D3/PSMD8/FUCA2/PSMA2/EVA1A/HRC/KLHL5/FBXL7/AMBN/FBXO27/FBXO44/CUL4B/DCAF7/MEN1/PSMC5/PSMC2/PSMB2/PSMD4/ASB1/CUL9/FBXL14/COPS8/GPS1/FBXL19/APP/CALU/CHM/RBX1/KLHL42/ZBTB16/MBTPS1/MSLN/PSMD1/AGTPBP1/FGF23/PSMB4/CCDC8/SOCS2/FBXL12/COPS3/CHGB/PSMD9/WDR5/PSMD3/FBXL16/WSB2/ASB13/CCNF/ALB/ATG12/ERCC8	172
BP	GO:0002224	toll-like receptor signaling pathway	78/7096	146/18670	0.0001042	0.002177	0.001623	MYD88/S100A9/S100A8/ITGAM/TLR1/TLR2/APPL2/BCL10/LYN/IRF7/TNIP2/IRF1/GRAMD4/TNFAIP3/RPS6KA3/CTSS/BIRC2/LY96/FLOT1/LGR4/LGMN/LILRA2/CTSK/IRAK3/NFKBIA/TICAM1/MAPKAPK3/IRAK4/CD36/TLR5/UBE2D3/TAB3/TRAF6/IKBKG/TLR4/PTPN22/TRAF3/UBE2D2/CACTIN/RSAD2/CASP8/CD300LF/CTSB/HMGB1/MFHAS1/TREML4/OTUD4/TAB1/MAPKAPK2/TNIP1/BIRC3/NR1H3/TNIP3/TLR10/UBC/CD300A/WDFY1/CYBA/RAB7B/FADD/HSP90B1/TLR8/REG3G/HAVCR2/MAP3K1/TLR3/LBP/TYRO3/RTN4/UNC93B1/TIRAP/CHUK/APPL1/NR1H4/TLR6/S100A14/RFTN1/MIR146A	78
BP	GO:0002244	hematopoietic progenitor cell differentiation	87/7096	166/18670	0.0001065	0.002216	0.001652	ZBTB24/PTPN6/SPI1/KCNAB2/PSMB9/PSMB8/KITLG/CBFB/PTPRC/LDB1/PSMA5/BATF/PSMD11/WDR7/PSME1/TGFB1/SIN3A/LMO2/PSMB10/PSMA1/PSMA4/CHD2/SRF/METTL3/ZBTB1/HYAL2/SLC7A6OS/FLT3/TCF12/ABL1/PSMB1/PSMC4/XRCC5/PSMD13/PSMB3/FLCN/TAL1/PSMB5/PSMD6/DHTKD1/HERC6/PSMC3/FNIP1/N4BP2L2/PSME3/BCL2/BMP4/PSMC6/MLF1/DPF2/SIPA1L3/OSM/INHBA/ACP6/TMEM91/PLEK/LIG4/HES1/NFE2L2/EIF2AK2/RBM47/JAM3/PLD4/AGPAT5/TNFRSF13B/PSEN1/PSMC1/ERCC2/PSMD8/PSMA2/C12orf29/PSMC5/PSMC2/PSMB2/PSMD4/CSF1R/SOX4/PTPRZ1/ADAR/PUS7/PSMD1/SLC8A3/PSMB4/RRS1/PSMD9/PSMD3/TOP2A	87
BP	GO:0001911	negative regulation of leukocyte mediated cytotoxicity	15/7096	18/18670	0.0001082	0.002238	0.001669	SERPINB9/PTPRC/LILRB1/IL7R/PPP3CB/HLA-F/HLA-E/CLEC12B/CRK/HLA-G/LGALS9/KIR2DL4/HAVCR2/SERPINB4/MICA	15
BP	GO:0032651	regulation of interleukin-1 beta production	52/7096	90/18670	0.0001082	0.002238	0.001669	IGF1/NOD2/CX3CR1/ACP5/CLEC7A/WNT5A/AZU1/ARG2/S1PR3/MNDA/LILRA5/NLRP3/TNFAIP3/LILRA2/NLRP12/JAK2/GSTP1/P2RX7/EGR1/AIM2/TRIM16/HSPB1/PANX1/SERPINB1/TLR4/CASP8/AGER/PML/HMGB1/TYROBP/SPHK1/MEFV/CASP1/LGALS9/FZD5/CPTP/F2R/TLR8/APOA1/TREM2/NLRP1/IFNG/NLRP2/CD33/FOXP1/APP/CX3CL1/CCL19/MALT1/CCR7/HMGB4/GHRL	52
BP	GO:0002695	negative regulation of leukocyte activation	91/7096	175/18670	0.0001087	0.002242	0.001671	CCR2/PTPN6/LILRB2/ANXA1/GRN/LYN/IRF1/ARG2/GPNMB/MNDA/LST1/PTPN2/TNFRSF14/BCL6/SMAD7/TNFAIP3/BANK1/FGL2/IL4R/CEBPB/CBFB/PTPRC/HFE/CD74/HMOX1/TNFRSF21/LILRB1/DUSP3/AXL/TGFB1/SOCS5/HLA-F/TSPAN32/IL20RB/PTPN22/ZBTB7B/SOCS6/ABR/DTX1/CASP3/IDO1/NFKBID/LDLR/CD300LF/HMGB1/TYROBP/HLA-G/CTLA4/GLMN/BCR/CST7/ATM/TIGIT/VSIG4/SCGB1A1/PDCD1LG2/NRARP/BMP4/PARP3/ID2/NR1H3/LAG3/INHBA/CD300A/CD274/RHBDD3/LGALS9/LAX1/PGLYRP4/FER/RABGEF1/BTN2A2/CNR2/HLX/TNFRSF13B/TNFSF4/IL13RA2/MERTK/PAG1/SOCS1/CD84/HAVCR2/INHA/SLA2/MICA/CD80/TBX21/TYRO3/CX3CL1/FOXF1/TWSG1	91
BP	GO:0045333	cellular respiration	99/7096	193/18670	0.00011	0.002262	0.001686	CBFA2T3/PINK1/MDH1/UQCRC2/SLC25A25/PANK2/UQCR11/NDUFA8/AIFM2/PRELID1/ETFA/NDUFC1/FASTKD1/HIF1A/ISCU/NDUFB11/NDUFS3/NDUFA3/CAT/ME3/NDUFA11/ETFDH/OGDH/IDH1/UQCR10/ACO1/COX7C/PPARGC1A/FLCN/ALDH5A1/IDH2/COX7A2L/DHTKD1/NDUFA4/MTFR1L/IMMP2L/SLC25A12/SHMT2/COX4I2/NDUFA1/MYBBP1A/CYP1A2/FH/MDH1B/COQ10B/OXA1L/ETFB/LYRM7/COQ9/COA6/COX15/NDUFA10/PDHB/CISD1/NDUFB1/NOA1/NDUFB5/IREB2/UQCRQ/SUCLG2/BLOC1S1/DLAT/TBRG4/NDUFS1/SLC25A13/IDH3A/NDUFB8/PDHA2/DNAJC15/SURF1/NDUFB6/IFNG/FAHD1/NR4A3/NDUFB3/SDHA/VCP/NDUFS7/NDUFAF2/NDUFV2/ND4/SDHD/ME2/TAZ/IDH3G/SNCA/COQ10A/UQCRB/SLC25A22/PNPT1/NDUFB2/SDHAF2/COX6C/MTFR2/NNT/NDUFS2/NDUFA7/FASTKD5/COX7B	99
BP	GO:0043470	regulation of carbohydrate catabolic process	51/7096	88/18670	0.0001127	0.00231	0.001722	IGF1/CBFA2T3/FBP1/STAT3/PFKFB3/NUP62/NUP160/NUP214/SLC2A6/P2RX7/NUPR1/PGAM1/EIF6/ZBTB7A/NUP85/HIF1A/SEH1L/INSR/PPP1R3D/NUP43/POM121/PFKFB4/PPARGC1A/SLC25A12/PRKAG2/MYOG/NCOR1/PFKFB1/NUP88/HDAC4/PPP1R3B/NUP107/DDIT4/PFKFB2/ARNT/PPP1CA/PPARA/NUP93/PRKAA1/PSEN1/NUP205/NUP50/IFNG/PRKAG1/OGT/PPP1CB/ESRRB/ZBTB20/APP/POM121C/AAAS	51
BP	GO:0032386	regulation of intracellular transport	198/7096	423/18670	0.0001158	0.002363	0.001762	ITGAM/FYN/EZR/APBA1/RAC2/LYN/PINK1/RAP1B/BARD1/NUP62/OAZ2/PTGS2/CHP1/HPS4/FLNA/SIRT4/MAP2K1/CIB1/FBXW7/NUP214/IL4R/RNF139/BCAP31/LAMP1/KHDRBS1/C2CD5/HMOX1/C12orf4/SCP2/RAN/GSK3B/EDEM1/HCLS1/CSNK2A2/MX2/TGFB1/RDX/STXBP1/MIEF1/RAB23/UNC13B/FIS1/GRIPAP1/SAR1B/PAK1/CD36/PCM1/STXBP2/LEP/PRKCD/UBE2D3/CEP131/HYAL2/RBM4/HTRA2/FBXL20/FGR/IFI27/CDK5/SFN/HRAS/SP100/DNAJC30/RAB3GAP1/MYBPC3/EMD/ZPR1/IL1B/GDI1/DTNBP1/UBR5/DHX9/UBE2J1/RAP1A/MDFIC/ATG13/EHD1/SPAG5/RAB29/PREPL/MAVS/UBE2G2/EDEM2/LRRK2/ARV1/MYO1C/NOLC1/RHOU/PDCD5/ADCY1/MLC1/SAR1A/ARF1/RBM27/ARIH2/LCP1/PLK3/P2RX1/ABLIM3/ADORA2B/VPS18/NAPA/BMP4/TBC1D20/NEDD4/INPP5K/BCAS3/MICALL2/KIF20B/UNC13D/PRKACA/RAB5A/GRASP/NDEL1/SH3TC2/MTMR2/UBL4B/GPR143/MAP2K2/CD300A/INPP5F/LMAN1/LGALS9/SREBF2/FER/RABGEF1/FZD5/CAMK2A/DMTN/CHRM2/DERL2/DNM1L/STX18/CHRNA4/HSPA1L/PPP1CC/INSIG1/CEMIP/TXN/YOD1/NUS1/ATP2A2/ANXA2P2/RIOK2/DVL1/PRKAA1/PSEN1/FMR1/IL13RA2/MDM2/RAB3A/MAPK1/CHRNB2/TCF7L2/P2RY4/PARL/SH3GLB1/YWHAE/MSN/SYT9/CD84/UBL5/RUFY3/IFNG/BAP1/CHP2/SYT1/KIF5B/B3GAT3/TMEM30A/SCFD1/SNX4/CACNB3/VAMP1/PKIA/SYT4/ANXA2/CDH3/ITGB1BP1/PDCD10/TM9SF4/RIMS2/FOXF1/WNT7A/TRIM58/ICE1/XPO4/PREB/SMO/TARDBP/P2RY1/WWC1/ERLEC1/AAAS/CTDSPL2/OS9/SEC16B/TRIM46	198
BP	GO:0045807	positive regulation of endocytosis	81/7096	153/18670	0.0001164	0.002363	0.001762	FPR2/IL2RG/DLL1/CLEC7A/APPL2/SLC11A1/WNT5A/AZU1/SOD1/LYAR/CAMK1D/ACTN4/FLOT1/PTPRC/IL15/HFE/TNF/APOE/RAB31/TBC1D5/MIB1/AXL/ARRB1/CD36/CD63/HNRNPK/PTX3/ITSN1/IL2RB/ABR/VEGFA/IL1B/CD151/SIRPB1/PLCG2/RAP1A/CD300LF/SFRP4/LRP1/CLU/LRRK2/CBLL1/APOA5/BICD1/BCR/ARF1/TOR1A/IL15RA/SH3GL1/DNM1/DNM2/SERPINE1/CD47/TSG101/ITGA2/CYBA/DNM1L/AP2A1/CALR/ABCA7/CAV3/ANXA2P2/FMR1/MERTK/APOA1/SIRPG/TREM2/IFNG/ANXA2/TSPAN1/PICK1/SNCA/CLIP3/CCL19/TULP1/APPL1/ATAD1/GREM1/RAB27A/PTPRJ/APLN	81
BP	GO:0070884	regulation of calcineurin-NFAT signaling cascade	24/7096	34/18670	0.0001172	0.002363	0.001762	IGF1/ATP2B4/CAMTA1/CHP1/CIB1/TNF/SLC9A1/GSK3B/DYRK2/MAPK7/NRG1/RCAN3/HOMER3/LMCD1/RCAN1/NFAT5/MYOZ1/FHL2/EFHB/CHP2/LACRT/MTOR/CHERP/ERBB3	24
BP	GO:0106056	regulation of calcineurin-mediated signaling	24/7096	34/18670	0.0001172	0.002363	0.001762	IGF1/ATP2B4/CAMTA1/CHP1/CIB1/TNF/SLC9A1/GSK3B/DYRK2/MAPK7/NRG1/RCAN3/HOMER3/LMCD1/RCAN1/NFAT5/MYOZ1/FHL2/EFHB/CHP2/LACRT/MTOR/CHERP/ERBB3	24
BP	GO:0033157	regulation of intracellular protein transport	113/7096	225/18670	0.0001175	0.002363	0.001762	ITGAM/FYN/RAC2/PINK1/BARD1/NUP62/OAZ2/PTGS2/CHP1/HPS4/FLNA/SIRT4/CIB1/FBXW7/BCAP31/C2CD5/RAN/GSK3B/EDEM1/HCLS1/CSNK2A2/TGFB1/MIEF1/RAB23/FIS1/GRIPAP1/SAR1B/PAK1/CD36/PCM1/LEP/PRKCD/UBE2D3/CEP131/HYAL2/HTRA2/IFI27/CDK5/SFN/HRAS/SP100/EMD/ZPR1/IL1B/GDI1/UBR5/UBE2J1/MDFIC/ATG13/RAB29/MAVS/UBE2G2/EDEM2/LRRK2/MYO1C/NOLC1/RHOU/PDCD5/SAR1A/ARIH2/LCP1/PLK3/ABLIM3/BMP4/INPP5K/BCAS3/MICALL2/KIF20B/PRKACA/GRASP/NDEL1/SH3TC2/UBL4B/LMAN1/SREBF2/FZD5/DMTN/DERL2/HSPA1L/INSIG1/CEMIP/TXN/YOD1/RIOK2/PRKAA1/PSEN1/MDM2/MAPK1/TCF7L2/PARL/SH3GLB1/YWHAE/UBL5/RUFY3/IFNG/BAP1/CHP2/KIF5B/B3GAT3/TMEM30A/CACNB3/PKIA/ITGB1BP1/PDCD10/TM9SF4/ICE1/XPO4/SMO/TARDBP/ERLEC1/CTDSPL2/OS9/SEC16B	113
BP	GO:1900542	regulation of purine nucleotide metabolic process	76/7096	142/18670	0.0001175	0.002363	0.001762	IGF1/CBFA2T3/PDK4/PINK1/FBP1/PGK1/STAT3/PFKFB3/NUP62/NUP160/NUP214/SLC2A6/P2RX7/NUPR1/PGAM1/PDK2/EIF6/ZBTB7A/NUP85/HIF1A/ISCU/SEH1L/INSR/NUP43/ENO1/DNAJC30/GSTZ1/UQCC2/POM121/PFKFB4/PPARGC1A/FLCN/COX7A2L/SLC25A12/SHMT2/PRKAG2/MYOG/NCOR1/ADORA2B/PFKFB1/NUP88/HDAC4/NUP107/PDK1/DDIT4/PGK2/PFKFB2/ARNT/DNM1L/PDP2/SLC25A33/PPARA/NUP93/PRKAA1/PSEN1/DNAJC15/NUP205/PID1/TREM2/NUP50/IFNG/PRKAG1/OGT/ATP7A/PDP1/ESRRB/ZBTB20/VCP/RHOA/TAZ/APP/SNCA/ABCD1/PDPR/POM121C/AAAS	76
BP	GO:0032956	regulation of actin cytoskeleton organization	164/7096	343/18670	0.000118	0.002364	0.001763	MYADM/S100A10/SIGLEC15/CDC42EP4/VASP/PTGER4/BST1/ARF6/STMN1/NOTCH2/FHOD1/TSC1/C9orf72/ARAP1/SORBS3/HCK/RHOBTB1/PLEKHG2/FLNA/RHOC/S1PR1/F11R/RGCC/TMSB10/SPIRE1/AKAP13/SLC9A1/ARHGDIA/IQGAP2/ARHGEF10L/ACTR2/CXCL12/RND3/TMOD3/LIMA1/HCLS1/EVL/TWF2/TGFB1/RDX/PFN1/CDC42EP2/PAK1/PTK2B/CFL2/CAPZA2/SWAP70/PRKCD/LATS1/GMFG/CORO1A/RHOG/BAIAP2/ARFGEF1/CAPG/NCK1/ARHGDIB/CDK5/HRAS/ABL1/FCHSD1/ARPC1A/CAPZA1/LRP1/CRK/PPM1F/MKKS/SH3BP1/TRPM2/RAC1/ARPIN/SPTBN1/CCDC88A/ARPC1B/MLST8/CDC42EP3/CYFIP1/MYO1C/RHOU/CORO1B/ARHGAP6/BBS4/LIMCH1/ARF1/DIXDC1/PAM/ARPC5L/NRP1/COTL1/TPM1/AVIL/INPP5K/BCAS3/CD47/RHOQ/CFL1/KANK1/TRIOBP/ARHGAP18/ADD3/RHOV/GRB2/PLEK/JMY/ACTR3B/PDGFA/SHANK1/FER/SEMA5A/RHOF/CD2AP/LPAR1/DMTN/ACTR3/RHOH/PXN/CLASP2/LMOD3/ABL2/CAV3/SCIN/JAM3/PREX1/SLIT2/CCL26/FSCN1/APOA1/ARPC4/TGFB3/RHOBTB3/SPTA1/HRG/SPTBN2/SYNPO2L/TACSTD2/TMEFF2/ARPC2/KANK3/CSF1R/MTOR/RHOA/PICK1/CX3CL1/ITGB1BP1/SNX9/GRHL3/MET/CCR7/WAS/ROCK2/RHOBTB2/CCL24/ASAP3/SHANK3/SERPINF2/BIN1/NCKAP1/FCHSD2/ALMS1/FZD10/MEF2C/SYNPO/PHPT1/FMN1	164
BP	GO:0032652	regulation of interleukin-1 production	58/7096	103/18670	0.00012	0.002398	0.001788	IGF1/NOD2/CX3CR1/ACP5/ANXA1/IL1R2/CLEC7A/WNT5A/AZU1/ARG2/S1PR3/MNDA/LILRA5/NLRP3/TNFAIP3/LILRA2/NLRP12/JAK2/GSTP1/P2RX7/EGR1/AIM2/TRIM16/HSPB1/PANX1/SERPINB1/TLR4/CASP8/AGER/PML/HMGB1/TYROBP/SPHK1/HDAC2/MEFV/CASP1/LGALS9/FZD5/CPTP/F2R/TLR8/APOA1/TREM2/NLRP1/HAVCR2/IFNG/NLRP2/CD33/FOXP1/APP/CX3CL1/CCL19/MALT1/CCR7/HMGB4/NR1H4/GHRL/IGHD	58
BP	GO:0051348	negative regulation of transferase activity	139/7096	285/18670	0.0001235	0.002461	0.001835	ITPRIP/PTPN6/DUSP1/PRKAR2B/CDKN2D/CDKN1A/SOCS3/DUSP6/LYN/MAD2L2/ZFP36/PPP2CA/FABP4/DUSP5/CSK/PTPN2/NUP62/CHP1/SMAD7/DUSP10/TNFAIP3/CIB1/RGS2/UCHL1/DUSP7/COX11/GSTP1/PTPRC/IRAK3/EPHB2/TESC/APOE/GSK3B/HMGCR/KAT2B/DUSP3/LRP5/HEXIM1/TAOK3/GADD45B/CBLB/GNAQ/DUSP18/SOCS5/HSPB1/ZFYVE28/HEG1/PRKCD/LATS1/PKIB/GMFG/ZGPAT/HYAL2/PIK3IP1/MBIP/DUSP2/TFAP4/PTPN22/ADARB1/CEBPA/DUS2/IGF1R/NCK1/CDKN2B/CASP3/SFN/NPM1/ABL1/PAK2/IL1B/DTNBP1/MVP/PTK6/CDKN1C/PAQR3/SH3BP5L/PPM1F/SIRT1/HEXIM2/BMP7/DUSP19/IRS2/SMYD3/SNX6/DUSP14/RGS3/DUSP4/DTX3L/PRKAG2/TARBP2/BMP4/PARP3/INPP5K/RGS14/CDKN1B/CDKN2C/TSG101/TRIB2/AKT1S1/CD300A/GSKIP/LAX1/SPRY1/CORO1C/RHOH/VPS25/SPRED1/CAV3/BAG2/CHORDC1/SPRY2/DVL1/DEPTOR/PSEN1/IPO7/SMCR8/NPRL2/SOCS1/IFNG/HIPK3/FGFR1OP/LATS2/DNAJA1/SMPD1/RB1/MEN1/YWHAG/PKIA/GPS1/POT1/ITGB1BP1/PDCD4/BAG5/ADAR/AIDA/CEP85/TAF7/PTPRJ/PHPT1	139
BP	GO:0046890	regulation of lipid biosynthetic process	101/7096	198/18670	0.0001244	0.002463	0.001836	FPR2/HTR2B/VDR/ASAH1/SLC27A1/PDK4/ANXA1/POR/STARD4/SOD1/ATP1A1/CAPN2/NFYC/GPAM/PTGS2/ADIPOR1/SIRT4/ABHD6/DDX20/FBXW7/RDH10/SIK1/SLC45A3/APOC1/SCARB1/SQLE/EGR1/TNF/CD74/ELOVL5/AKR1C3/NFKB1/RAN/IGFBP7/APOE/HMGCR/LPGAT1/EIF6/CDK4/HMGCS1/SCD/ENHO/LEP/NR1H2/ERLIN1/PRKCD/BMP2/IL1B/SAMD8/LDLR/ERLIN2/FDPS/ACACB/CREB1/IDH1/SIRT1/CREBL2/DGAT2/FABP3/PDGFB/PPARGC1A/FGF1/RAB38/TM7SF2/APOA5/ORMDL2/SPHK1/IDI1/PRKAG2/BMP5/ORMDL3/SCAP/ABCG1/NR1H3/SC5D/PDGFA/SREBF2/ACADVL/SERPINA12/INSIG1/FABP5/BRCA1/ADIPOR2/PRKAA1/APOA1/CYP27B1/PLA2G6/SNAI1/IFNG/ZBTB20/MTOR/MBTPS2/ELOVL6/ABCD1/LPCAT1/SMPD2/MBTPS1/KPNB1/THRSP/NR1H4/FAM3A	101
BP	GO:0021782	glial cell development	64/7096	116/18670	0.0001244	0.002463	0.001836	S100A8/FPR2/TLR2/MPP5/DLL1/GRN/LYN/SKI/SOD1/VIM/LAMB2/GSTP1/TNF/KRAS/MIR142/TGFB1/LAMC3/ROR2/NRG1/B4GALT6/TLR4/EIF2B5/CDK5/IL1B/AGER/HDAC11/LDLR/LRP1/CLU/NDRG1/ZNF488/TTBK1/IL6/BACE2/DICER1/HDAC10/ID2/ROR1/ADAM22/SH3TC2/LGI4/B4GALT5/LPAR1/CNTF/IFNGR1/EGFR/MXRA8/PSEN1/ERCC2/TREM2/EIF2B1/IFNG/EIF2B3/PICK1/APP/DAG1/SOX4/TSPAN2/EIF2B2/PLP1/PHGDH/SMO/NTRK2/POU3F1	64
BP	GO:0032970	regulation of actin filament-based process	183/7096	388/18670	0.0001252	0.002471	0.001842	MYADM/S100A10/SIGLEC15/CDC42EP4/VASP/PTGER4/BST1/ARF6/STMN1/NOTCH2/FHOD1/TSC1/ATP1A1/C9orf72/ARAP1/SORBS3/HCK/RHOBTB1/PLEKHG2/FLNA/RHOC/S1PR1/F11R/RGCC/TMSB10/SPIRE1/AKAP13/SLC9A1/ARHGDIA/IQGAP2/ARHGEF10L/ACTR2/CXCL12/RND3/TMOD3/LIMA1/HCLS1/EVL/TWF2/TGFB1/RDX/KCNE3/PFN1/CDC42EP2/PAK1/PTK2B/CFL2/CAPZA2/SWAP70/PRKCD/LATS1/GMFG/CORO1A/RHOG/BAIAP2/ARFGEF1/CAPG/ABRACL/NCK1/ARHGDIB/CDK5/PDE4B/HRAS/ABL1/FCHSD1/MYBPC3/ARPC1A/CAPZA1/LRP1/CRK/PPM1F/TRPM4/MKKS/SH3BP1/TRPM2/RAC1/ARPIN/SPTBN1/CCDC88A/ARPC1B/MLST8/CDC42EP3/CYFIP1/MYO1C/RHOU/SUMO1/CORO1B/SRI/ARHGAP6/MYH9/BBS4/LIMCH1/ARF1/DIXDC1/CNN2/CTNNA3/HCN4/PAM/ARPC5L/NRP1/COTL1/TPM1/AVIL/INPP5K/BCAS3/CD47/RHOQ/CFL1/KANK1/TRIOBP/ARHGAP18/ADD3/RHOV/RANGRF/GRB2/PLEK/JMY/ACTR3B/PDGFA/SHANK1/FER/SEMA5A/RHOF/CD2AP/LPAR1/DMTN/ACTR3/RHOH/PXN/CAMK2D/CLASP2/LMOD3/DSC2/ABL2/CAV3/ATP2A2/SCIN/JAM3/PREX1/SLIT2/CCL26/FSCN1/APOA1/ARPC4/TGFB3/RHOBTB3/PKP2/SPTA1/HRG/SPTBN2/SYNPO2L/TACSTD2/TMEFF2/ARPC2/KANK3/CSF1R/MTOR/RHOA/PICK1/CX3CL1/ITGB1BP1/SNX9/GRHL3/MET/FGF13/ATP1A2/CCR7/WAS/ROCK2/RHOBTB2/CCL24/ASAP3/SHANK3/SERPINF2/BIN1/NCKAP1/FCHSD2/ALMS1/FZD10/MEF2C/SYNPO/PHPT1/FMN1	183
BP	GO:0043620	regulation of DNA-templated transcription in response to stress	69/7096	127/18670	0.0001303	0.002565	0.001912	EPAS1/KLF2/RBPJ/TMBIM6/PSMB9/RPS6KA3/PSMB8/CEBPB/EGR1/PSMA5/PSMD11/HMOX1/PSME1/ATF4/RELA/HIGD1A/SIN3A/DNAJB1/HIF1A/HSF2/PSMB10/MAPK7/PSMA1/PSMA4/HSF4/HSPA5/NCK1/VEGFA/EGLN1/PSMB1/PSMC4/PSMD13/PSMB3/HIF1AN/EGLN3/CITED2/PSMB5/PSMD6/MUC1/PSMC3/PSME3/CHD6/NEDD4/PSMC6/RGS14/UBC/ARNT/NFE2L2/IMPACT/E2F4/PSMC1/CUL2/RBL2/PSMD8/BCLAF1/PSMA2/BACH1/PSMC5/PSMC2/PSMB2/PSMD4/MBTPS2/RBX1/PSMD1/PSMB4/SESN2/PSMD9/PSMD3/ATF6B	69
BP	GO:0051168	nuclear export	99/7096	194/18670	0.0001415	0.002775	0.002069	TSC1/NXF1/SRSF5/BARD1/NUP62/NUP160/CHP1/STRADB/RITA1/CHTOP/NUP214/ENY2/AGFG1/KHDRBS1/AKAP13/RAN/GSK3B/ALYREF/RNPS1/EIF6/MAGOHB/TGFB1/SARNP/NUP85/NXT1/SEH1L/YTHDC1/NUP43/IFI27/HNRNPA1/CDK5/SFN/NPM1/SP100/HNRNPA2B1/EMD/IL1B/RBM8A/FYTTD1/DDX19B/DHX9/U2AF1/POM121/ZNF593/SRSF3/SYMPK/XPOT/EGR2/CCHCR1/CPSF3/RBM27/FIP1L1/LSG1/NUP88/THOC2/SRSF6/SRSF7/PRKACA/CSE1L/NUP107/CDC40/THOC5/POLR2D/CALR/AHCYL1/U2AF1L4/TXN/EIF5A/NUP93/LTV1/THOC6/RIOK2/SSB/SRRM1/NUP205/MDM2/TCF7L2/YWHAE/PHAX/ANKLE1/SRSF4/EIF4E/NUP50/ATXN1/DHX38/MCM3AP/PCID2/CPSF2/CPSF1/MALT1/STRADA/XPO4/EIF4ENIF1/RRS1/POM121C/AAAS/CTDSPL2/NEMF/UPF1	99
BP	GO:0016236	macroautophagy	143/7096	295/18670	0.0001426	0.002789	0.002079	ATP6V0D2/STAM/ATG7/PINK1/ATG3/TSC1/MCOLN1/C9orf72/GNAI3/GAPDH/RNF41/ATP6V1C1/FEZ2/ULK2/ATG14/UCHL1/SEC22B/SQSTM1/WDR81/LAMP2/HMOX1/ATP6V0C/NUPR1/TRIM13/VPS37B/PLAA/TBC1D5/CHMP4B/CSNK2A2/CDC37/EXOC1/RAB23/HIF1A/MAP1LC3A/DYNLL2/ATG101/IKBKG/TCIRG1/HTRA2/TP53INP2/QSOX1/UBXN2B/TMEM41B/SPTLC2/CDK5/CASP3/ATP6V1A/TEX264/RAB3GAP1/LAMTOR1/CLN3/NSFL1C/VPS33A/VPS37C/VTA1/RRAGD/CSNK2B/ATG13/WIPI1/NPRL3/SIRT1/RAB33B/GPSM1/ATP6V1B2/MLST8/LRRK2/MAP1LC3C/ATP6V1D/SNX6/ATG9A/HDAC10/PHF23/PRKAG2/ZFYVE1/VPS13D/LAMTOR4/MAPK8/EPM2A/UBQLN2/EI24/ATG4B/NEDD4/ATP6V0E2/CHMP2A/TOMM22/PACS2/TSG101/PRKACA/RAB5A/ADRB2/ATG2B/HGS/WDR45B/TOMM40/USP30/VPS4B/ATP6V1G2/RRAGA/TOMM20/VDAC1/LAMTOR5/VPS25/ULK1/YOD1/SESN1/PRKAA1/PSEN1/MTMR3/SNX5/STX12/SH3GLB1/IFT20/SMCR8/NPRL2/EXOC4/ATG16L2/PRKAG1/TOMM5/GABARAPL1/SCFD1/CLEC16A/RNF5/LACRT/ATG4A/VPS16/OPTN/VPS26B/SNAP29/TRAPPC8/VCP/MTOR/PIM2/ERN1/ATP6V1B1/NBR1/LZTS1/SESN2/SLC38A9/CAPNS1/SNX32/ATG12/PRKAB1/FUNDC1	143
BP	GO:0043406	positive regulation of MAP kinase activity	127/7096	258/18670	0.0001437	0.002801	0.002088	IGF1/HTR2B/NOD2/S100A12/FPR1/PEA15/DUSP6/WNT5A/DUSP5/CSK/SOD1/ERP29/FLT1/CD40/KITLG/MIF/MAP2K1/DUSP7/JAK2/MAP3K8/PTPRC/P2RX7/MAGED1/ALK/UBE2N/ADAM8/DVL2/TNF/EZH2/CD74/AKAP13/ERCC6/KRAS/ZEB2/MAP3K4/MAPKAPK3/TGFB1/TAOK3/GADD45B/HGF/ARRB1/PAK1/MAP4K5/PTK2B/ROR2/INSR/TAB3/NRG1/TRAF6/IKBKG/TLR4/FLT3/PDGFC/TPD52L1/BMP2/VEGFA/HRAS/IL1B/CSPG4/AGER/MAP3K12/RASGRP1/MDFIC/SHC1/PIK3R6/TNFRSF11A/PDE6G/CRK/RAF1/DUSP19/MAP4K2/MAP4K3/PDGFB/LRRK2/FGF1/PROK1/MAPKAPK5/TAB1/ADORA2B/MAPKAPK2/BMP4/MAP3K6/MAP4K1/LPAR3/MLKL/UBC/MAP2K2/MAP3K11/PDGFA/FZD5/BIRC7/LPAR1/MAP3K5/PROK2/F2R/MOS/EIF2AK2/EGFR/MUL1/TRAF2/FZD4/ADAM9/PRKAA1/PSEN1/MAPK1/MAP2K4/TGFB3/MAP3K13/MAPK11/RET/MAP3K1/MAP2K5/PIK3CG/ERN1/PDCD10/CCL19/GHR/DAXX/CD24/TLR6/PDGFD/GHRL/FZD10/PIK3CB/NRK/SASH1/MAP3K9	127
BP	GO:0002702	positive regulation of production of molecular mediator of immune response	54/7096	95/18670	0.0001456	0.002819	0.002102	NOD2/BCL10/MAD2L2/DDX21/WNT5A/STAT6/TNFRSF14/NLRP3/CD40/MIF/IL4R/PTPRC/CD74/GPRC5B/LILRB1/TICAM1/CD226/TGFB1/IL18R1/FFAR2/CD36/HLA-F/TRAF6/TLR4/DDX58/HLA-E/RSAD2/IL1B/IL1R1/GPI/HLA-G/MAVS/IL6/MLH1/CLCF1/DDX1/FZD5/KIR2DL4/IL18/TRAF2/TFRC/TNFSF4/TNFRSF4/NR4A3/EXOSC3/TRIM6/PRKCZ/TBX21/EXOSC6/MALT1/CD244/PAXIP1/ATAD5/RBP4	54
BP	GO:0042116	macrophage activation	54/7096	95/18670	0.0001456	0.002819	0.002102	ITGAM/FPR2/TLR1/TLR2/NAMPT/GRN/SBNO2/SLC11A1/TNIP2/WNT5A/AZU1/JMJD6/MIF/CD93/CTSC/IL4R/JAK2/PTPRC/TNF/CD74/TICAM1/MIR142/TLR4/CEBPA/AIF1/AGER/LDLR/CLU/TYROBP/MFHAS1/TTBK1/IL6/LRRK2/CST7/ATM/VSIG4/CRTC3/SPHK1/NR1H3/IFNGR1/TLR8/TREM2/RORA/HAVCR2/IFNG/SLC7A2/SUCNR1/TLR3/LBP/FOXP1/APP/SNCA/CX3CL1/TLR6	54
BP	GO:0042089	cytokine biosynthetic process	67/7096	123/18670	0.0001462	0.002819	0.002102	KLF4/CCR2/TLR1/CX3CR1/CLEC7A/BCL10/IRF7/ZFP36/IRF1/WNT5A/AZU1/STAT3/CEBPG/NLRP12/CEBPB/JAK2/PTPRC/EGR1/TNF/CD74/HMOX1/NFKB1/IL1RAP/LILRB1/TICAM1/RELA/NMI/PTAFR/HSPB1/TRAF6/TLR4/IL1B/AGER/UBE2J1/TYROBP/IL6/GLMN/MAPKAPK2/TRIB2/IL1A/LAG3/INHBA/PCSK5/EBI3/CYBB/IL18/CD276/CMA1/PSEN1/TLR8/SIGIRR/IFNG/CD4/TLR3/INHA/MAP2K5/LBP/TNFRSF13C/IL12B/ASB1/CD80/PRKCQ/APP/TIRAP/CD3E/TLR6/GHRL	67
BP	GO:0006664	glycolipid metabolic process	61/7096	110/18670	0.0001463	0.002819	0.002102	FUCA1/ASAH1/HEXB/CTSA/GM2A/ESYT2/PIGV/PIGP/SUMF1/PSAP/PIGK/HEXA/SUMF2/SCCPDH/PIGN/GALC/PRKCD/B4GALT6/B3GNT5/CLN3/ST6GALNAC4/ST3GAL2/PIGF/GLA/PIGB/DPM1/GPAA1/ALDH5A1/CREM/ENPP7/PIGM/BAX/MPPE1/B4GALNT1/NAGA/PIGQ/GAL3ST4/CLN6/B4GALT5/PIGO/UGCG/ST8SIA4/CPTP/PIGH/STS/ARSA/ST6GALNAC5/PRKAA1/DPM3/CERK/PIGT/NEU1/ST6GALNAC3/SMPD1/ST6GALNAC6/SMPD2/PGAP3/ST8SIA1/ST3GAL5/GLTP/PGAP1	61
BP	GO:0071901	negative regulation of protein serine/threonine kinase activity	77/7096	145/18670	0.0001488	0.002859	0.002131	PTPN6/DUSP1/PRKAR2B/CDKN2D/CDKN1A/DUSP6/LYN/PPP2CA/DUSP5/NUP62/DUSP10/TNFAIP3/CIB1/RGS2/UCHL1/DUSP7/GSTP1/IRAK3/APOE/HMGCR/KAT2B/DUSP3/LRP5/HEXIM1/DUSP18/HSPB1/HEG1/PRKCD/LATS1/PKIB/HYAL2/MBIP/DUSP2/TFAP4/PTPN22/CEBPA/CDKN2B/CASP3/SFN/ABL1/IL1B/DTNBP1/CDKN1C/PAQR3/SIRT1/HEXIM2/BMP7/DUSP19/DUSP14/RGS3/DUSP4/PRKAG2/BMP4/INPP5K/RGS14/CDKN1B/CDKN2C/CD300A/LAX1/SPRY1/SPRED1/CAV3/CHORDC1/SPRY2/IPO7/HIPK3/LATS2/DNAJA1/SMPD1/RB1/MEN1/YWHAG/PKIA/GPS1/PDCD4/AIDA/PTPRJ	77
BP	GO:0002716	negative regulation of natural killer cell mediated immunity	13/7096	15/18670	0.0001512	0.002888	0.002153	SERPINB9/LILRB1/HLA-F/HLA-E/CLEC12B/CRK/HLA-G/CD96/LGALS9/KIR2DL4/HAVCR2/SERPINB4/MICA	13
BP	GO:0045410	positive regulation of interleukin-6 biosynthetic process	13/7096	15/18670	0.0001512	0.002888	0.002153	TLR1/CLEC7A/STAT3/TNF/CD74/PTAFR/TRAF6/IL1B/AGER/TYROBP/APP/TIRAP/TLR6	13
BP	GO:0006509	membrane protein ectodomain proteolysis	28/7096	42/18670	0.0001551	0.002954	0.002202	LRIG2/TIMP2/ADAM19/P2RX7/ADAM8/TNF/PSENEN/APOE/SPPL2A/IL1B/FURIN/SNX33/TIMP4/BACE2/PSEN2/MYH9/TIMP1/ADAM17/ADAM9/PSEN1/ERAP1/IFNG/PRTN3/PRKCQ/DAG1/SNX9/APH1A/PACSIN3	28
BP	GO:0050792	regulation of viral process	105/7096	208/18670	0.000156	0.002957	0.002204	TRIM32/ZFP36/FCN1/PLSCR1/STAT1/OASL/LAMP3/IFITM2/TNF/IFITM1/CD74/CHD1/TRIM13/VPS37B/IFITM3/APOE/CHMP4B/MORC2/ISG20/STAU1/PTX3/TRIM26/DDB1/TFAP4/ADARB1/OAS3/IFI27/IGF2R/RSAD2/TAF11/CCL5/DHX9/GTF2F2/SRPK2/MDFIC/PML/POLR2L/ISG15/VAPB/TRIM11/APOBEC3G/MAVS/CTDP1/CDK9/APOBEC3C/IFIT5/POLR2H/DDX3X/ILF3/BANF1/ZC3HAV1/PSMC3/TRIM21/TARBP2/BCL2/CCL8/TBC1D20/TNIP1/CHMP2A/INPP5K/CCNK/TSG101/CFL1/MX1/TOP2B/LGALS1/SUPT4H1/SETDB1/RNASEL/RSF1/GTF2F1/LGALS9/IFIT1/SRPK1/VPS4B/POLR2F/POLR2D/EIF2AK2/CNOT7/PKN2/MID2/ANXA2P2/POLR2K/FMR1/FBXL2/SMC3/NELFCD/TRIM15/CD4/TRIM6/EIF2AK4/PC/CSF1R/ANXA2/HPN/CCNT1/ADAR/CCL4/PPIB/POLR2I/NUCKS1/TARDBP/TOP2A/APCS/BTBD17	105
BP	GO:0032816	positive regulation of natural killer cell activation	16/7096	20/18670	0.0001562	0.002957	0.002204	IL15/LAMP1/TICAM1/AXL/HLA-F/ZBTB1/FLT3LG/HLA-E/RASGRP1/TYROBP/TOX/BLOC1S3/IL18/AP1G1/IL12B/IL23A	16
BP	GO:0002292	T cell differentiation involved in immune response	41/7096	68/18670	0.0001576	0.002975	0.002218	PTGER4/NFKBIZ/ANXA1/TSC1/CLEC4D/STAT6/STAT3/BCL6/NLRP3/CLEC4E/SMAD7/FGL2/LY9/IL4R/BATF/IL18R1/SOCS5/SEMA4A/ZBTB7B/RELB/NFKBID/HMGB1/IL6/IL12RB1/LGALS9/HLX/IL18/TNFSF4/RORA/IFNG/ATP7A/IL12B/PRKCZ/CD80/TBX21/MTOR/FOXP1/GPR183/CCL19/MALT1/IL23A	41
BP	GO:0000086	G2/M transition of mitotic cell cycle	122/7096	247/18670	0.0001603	0.003007	0.002242	PRKAR2B/TUBA1A/CDKN1A/NINL/PSMB9/CUL1/RAB11A/PSMB8/RNASEH2B/HUS1B/ODF2/PSMA5/PSMD11/KHDRBS1/SKP2/HAUS8/PSME1/GPR132/CNTRL/CDK4/TAOK3/SIN3A/CEP164/ZNF830/PSMB10/PCM1/MTA3/PSMA1/PSMA4/CSNK1D/LATS1/CEP131/DBF4B/SYF2/TPD52L1/CDKN2B/PPM1D/SFI1/CCNH/PAFAH1B1/RAD51B/CDK5RAP2/PSMB1/PSMC4/DONSON/CEP76/PSMD13/MAPRE1/FBXL18/PSMB3/CCND1/LCMT1/PSMB5/PSMD6/ATM/CSNK1E/HAUS2/PSMC3/PLK3/PSME3/RAD17/DNM2/KDM8/PSMC6/PRKACA/CKAP5/DCTN2/FHL1/CDC25A/CEP152/TUBA4A/VPS4B/FOXO4/TICRR/MIIP/DTL/CEP63/PLCB1/BRCA1/CCNY/CEP57/RCC2/CETN2/HAUS5/TUBB4A/HAUS1/YWHAE/PSMC1/CLSPN/WEE1/PSMD8/PSMA2/FBXL7/TOPBP1/FGFR1OP/BACH1/MASTL/PPP1CB/CCNA2/YWHAG/PSMC5/OPTN/PKIA/ESRRB/PSMC2/PSMB2/PSMD4/AURKA/BRSK1/APP/RBX1/CEP78/CCNB3/PSMD1/WNT10B/PSMB4/FBXL12/ZFYVE19/PSMD9/KIF14/PSMD3/ALMS1	122
BP	GO:1903362	regulation of cellular protein catabolic process	122/7096	247/18670	0.0001603	0.003007	0.002242	CBFA2T3/EZR/TMTC3/PINK1/WDR91/SMAD7/TNFAIP3/KEAP1/DDRGK1/FBXW7/CTSC/ATRAID/RNF139/LAMP3/BCAP31/HFE/RAD23B/FHIT/NUPR1/RYBP/APOE/GSK3B/PSME1/MAGEF1/RNF19B/FBXL5/EDEM1/CSNK2A2/UBE3A/UBE2K/RDX/ALAD/SGTA/ZFAND2A/SOCS5/PTK2B/CSNK1D/PTTG1IP/LATS1/RNF217/CEBPA/PLK2/ANKIB1/GCLC/OPHN1/PSMC4/FURIN/UQCC2/LDLR/SDCBP/UBE2J1/ARAF/PML/LRP1/CLU/UCHL5/UBE2G2/EDEM2/LRRK2/SUMO1/GLMN/PTK2/HSPBP1/CSNK1A1/CSNK1E/RNFT1/ARIH2/PLK3/PSME3/DISC1/UBQLN2/TRIB2/PRKACA/MGAT3/BBS7/DET1/NKD2/KLHL40/DERL2/STUB1/NFE2L2/ATXN3/COMMD1/NFE2L1/LAPTM4B/YOD1/CAV3/BAG2/USP7/ANXA2P2/DVL1/MAP1A/WNT1/PSEN1/FMR1/MDM2/MSN/PSMC1/TREM2/UBXN1/OGT/RNF185/HSP90AB1/CLEC16A/FOXF2/PSMC2/GPX1/VCP/ANXA2/AURKA/RBX1/BAG5/RGP1/USP19/SMARCC1/KCNE2/CHFR/WNT10B/ERLEC1/OS9/MAPK9/RHBDF1	122
BP	GO:0002260	lymphocyte homeostasis	38/7096	62/18670	0.0001676	0.003126	0.00233	SH2B2/SLC40A1/TSC22D3/SKIL/BCL10/LYN/PMAIP1/SLC46A2/TNFAIP3/MIF/P2RX7/DOCK10/CD74/TGFB1/PPP3CB/HIF1A/TNFSF13B/CORO1A/TCIRG1/CASP3/ABL1/BCL2L11/BCL2/BAX/PPP2R3C/LGALS9/ADA/FADD/DOCK11/TNFRSF13B/SPTA1/GAPT/TNFRSF13C/FOXN1/BAK1/CACNA1F/LAT/MEF2C	38
BP	GO:0006220	pyrimidine nucleotide metabolic process	38/7096	62/18670	0.0001676	0.003126	0.00233	CDS1/UPP1/GPAM/CDS2/AK3/NEIL2/UNG/NT5C/CDADC1/CTPS2/AGPAT3/CMPK1/CMPK2/CDIPT/TDG/AGPAT4/NME3/NME4/NME1/PRPS1/TYMS/DCK/SHMT1/UCK1/TBPL1/AGPAT5/DCTD/CTPS1/CAD/DCTPP1/AGPAT1/UCKL1/NT5M/UPP2/DUT/AGPAT2/MBD4/SMUG1	38
BP	GO:0043903	regulation of symbiosis, encompassing mutualism through parasitism	111/7096	222/18670	0.0001683	0.003131	0.002334	TRIM32/ZFP36/FCN1/PLSCR1/GAPDH/STAT1/OASL/LAMP3/IFITM2/TNF/IFITM1/CD74/CHD1/TRIM13/VPS37B/IFITM3/APOE/CHMP4B/MORC2/ISG20/STAU1/PTX3/TRIM26/DDB1/TFAP4/ADARB1/OAS3/IFI27/IGF2R/RSAD2/TAF11/CCL5/DHX9/GTF2F2/SRPK2/MDFIC/PML/POLR2L/ISG15/VAPB/TRIM11/APOBEC3G/MAVS/CTDP1/CDK9/APOBEC3C/IFIT5/POLR2H/DDX3X/ILF3/BANF1/ZC3HAV1/PSMC3/BCL2L11/TRIM21/TARBP2/BCL2/CCL8/TBC1D20/TNIP1/CHMP2A/INPP5K/CCNK/TSG101/CFL1/MX1/TOP2B/LGALS1/SUPT4H1/SETDB1/RNASEL/RSF1/GTF2F1/LGALS9/IFIT1/SRPK1/VPS4B/POLR2F/POLR2D/EIF2AK2/CNOT7/PKN2/MID2/ANXA2P2/POLR2K/FMR1/FBXL2/BAD/SMC3/FUCA2/NELFCD/TRIM15/CD4/TRIM6/EIF2AK4/PC/CSF1R/ANXA2/HPN/CCNT1/ADAR/CCL4/PPIB/POLR2I/NUCKS1/TARDBP/TOP2A/APCS/CXCL6/EXOC2/BTBD17	111
BP	GO:0001774	microglial cell activation	31/7096	48/18670	0.0001694	0.003134	0.002336	ITGAM/FPR2/TLR2/NAMPT/GRN/AZU1/CTSC/JAK2/PTPRC/TNF/MIR142/AIF1/AGER/LDLR/CLU/TYROBP/TTBK1/IL6/LRRK2/CST7/ATM/SPHK1/IFNGR1/TLR8/TREM2/IFNG/TLR3/APP/SNCA/CX3CL1/TLR6	31
BP	GO:0002269	leukocyte activation involved in inflammatory response	31/7096	48/18670	0.0001694	0.003134	0.002336	ITGAM/FPR2/TLR2/NAMPT/GRN/AZU1/CTSC/JAK2/PTPRC/TNF/MIR142/AIF1/AGER/LDLR/CLU/TYROBP/TTBK1/IL6/LRRK2/CST7/ATM/SPHK1/IFNGR1/TLR8/TREM2/IFNG/TLR3/APP/SNCA/CX3CL1/TLR6	31
BP	GO:0002294	CD4-positive, alpha-beta T cell differentiation involved in immune response	37/7096	60/18670	0.00017	0.003135	0.002337	PTGER4/NFKBIZ/ANXA1/STAT6/STAT3/BCL6/NLRP3/SMAD7/LY9/IL4R/BATF/IL18R1/SOCS5/SEMA4A/ZBTB7B/RELB/NFKBID/HMGB1/IL6/IL12RB1/LGALS9/HLX/IL18/TNFSF4/RORA/IFNG/ATP7A/IL12B/PRKCZ/CD80/TBX21/MTOR/FOXP1/GPR183/CCL19/MALT1/IL23A	37
BP	GO:1900371	regulation of purine nucleotide biosynthetic process	64/7096	117/18670	0.0001735	0.003182	0.002372	IGF1/CBFA2T3/PDK4/PINK1/FBP1/STAT3/PFKFB3/NUP62/NUP160/NUP214/SLC2A6/P2RX7/NUPR1/PGAM1/PDK2/EIF6/ZBTB7A/NUP85/HIF1A/SEH1L/INSR/NUP43/ENO1/DNAJC30/GSTZ1/POM121/PFKFB4/PPARGC1A/FLCN/SLC25A12/PRKAG2/MYOG/NCOR1/ADORA2B/PFKFB1/NUP88/HDAC4/NUP107/PDK1/DDIT4/PFKFB2/ARNT/PDP2/PPARA/NUP93/PRKAA1/PSEN1/NUP205/PID1/TREM2/NUP50/IFNG/PRKAG1/OGT/PDP1/ESRRB/ZBTB20/VCP/TAZ/APP/SNCA/PDPR/POM121C/AAAS	64
BP	GO:0032663	regulation of interleukin-2 production	34/7096	54/18670	0.0001735	0.003182	0.002372	CCR2/EZR/ANXA1/CLEC7A/ZFP36/GBP1/TNFAIP3/PTPRC/TRAF6/IL20RB/PDE4B/ABL1/IL1B/HOMER3/SPTBN1/GLMN/VSIG4/KAT5/HDAC7/PRKD2/IL1A/LAG3/TRAF2/HAVCR2/CD34/CD4/CD80/TBX21/PRKCQ/NAV3/CD83/MALT1/CD3E/NR1H4	34
BP	GO:0006066	alcohol metabolic process	172/7096	364/18670	0.0001748	0.003196	0.002383	IGF1/MYOF/VDR/ASAH1/ALDH3A2/GCH1/SLC5A3/POR/CYP27A1/SOD1/CBR4/AKR1B1/NFYC/GPAM/NPC2/PPARD/ALDH1A1/GDE1/RDH10/ADH5/APOC1/GK/SCARB1/SQLE/RETSAT/SOAT1/TNF/IMPAD1/PCBD1/AKR1C3/CETP/NFKB1/INPP1/RAN/APOE/HMGCR/AKR7A2/LIMA1/GALK1/DHRS3/TPI1/DHRS9/HDLBP/CLN8/OSBPL1A/HMGCS1/CYP1B1/PTAFR/IP6K1/SCD/PTK2B/PCK2/LEP/SYNJ1/AKR1A1/ERLIN1/P2RY6/RDH16/SGPP2/NAPEPLD/CNBP/CEBPA/BMP2/AKR1C1/SPTLC2/CAT/ACLY/ABCA1/IL1B/ALDH2/PLCG2/PPIP5K2/LDLR/PLB1/LMF1/ERLIN2/FDPS/QDPR/ACACB/COQ3/SYNJ2/APOBR/DGAT2/PTS/DPM1/OCRL/RDH12/G6PD/FGF1/ARV1/APOL1/GNB3/TM7SF2/APOA5/SPR/SPHK1/MSMO1/IDI1/BMP5/NUDT3/CYP2D6/LCAT/RXRA/CYP1A2/PLCL1/GK5/SCAP/INPP5K/IMPA2/ABCG1/APOL2/SC5D/CH25H/MTMR2/CLN6/RDH5/PLEK/SREBF2/SORD/ACADVL/CYB5R3/CHKA/AKR1B10/FDX1/PLCD1/ADH1B/NFE2L1/SERPINA12/INSIG1/PLCB1/DHFR/NUS1/DHDDS/PLD4/ACAA2/IPPK/SRD5A3/PLCD4/ACER3/PRKAA1/APOA1/CYP27B1/MINPP1/PLCL2/IFNG/SMPD1/SULT1B1/DBH/PCBD2/MBTPS2/APP/SNCA/ELOVL6/CD244/MBTPS1/KPNB1/CYP46A1/CACNA1H/INPPL1/ADH7/ADCYAP1R1/NR1H4/RBP4/P2RY1/DPAGT1/NTSR1/PNPLA4/HAO1/SNX17/INPP5A/DEGS2/IMPA1	172
BP	GO:0044839	cell cycle G2/M phase transition	130/7096	266/18670	0.0001796	0.003275	0.002441	PRKAR2B/TUBA1A/CDKN1A/NINL/PSMB9/CUL1/RAB11A/PSMB8/RNASEH2B/HUS1B/ATF5/ODF2/PSMA5/PSMD11/KHDRBS1/SKP2/HAUS8/PSME1/GPR132/CNTRL/CDK4/TAOK3/SIN3A/CEP164/ZNF830/PSMB10/PCM1/MTA3/PSMA1/PSMA4/CSNK1D/LATS1/CEP131/UIMC1/DBF4B/SYF2/TPD52L1/CDKN2B/NPM1/PPM1D/SFI1/CCNH/PAFAH1B1/RAD51B/CDK5RAP2/PSMB1/PSMC4/DONSON/CEP76/PSMD13/MAPRE1/FBXL18/PSMB3/CCND1/LCMT1/PSMB5/PSMD6/ATM/CSNK1E/HAUS2/PSMC3/AKAP8/PLK3/PSME3/RAD17/DNM2/KDM8/PSMC6/PRKACA/CKAP5/DCTN2/FHL1/CDC25A/CEP152/TUBA4A/VPS4B/FOXO4/TICRR/MIIP/DTL/CEP63/DYRK3/PLCB1/BRCA1/CCNY/CEP57/RCC2/CETN2/HAUS5/TUBB4A/HAUS1/YWHAE/PSMC1/CLSPN/WEE1/PSMD8/PSMA2/FBXL7/TOPBP1/FGFR1OP/BACH1/MASTL/PPP1CB/CCNA2/YWHAG/PSMC5/OPTN/PKIA/ESRRB/PSMC2/PSMB2/PSMD4/AURKA/BRSK1/APP/RBX1/BRCC3/CEP78/CCNB3/PSMD1/PAXIP1/ATAD5/WNT10B/PSMB4/FBXL12/ZFYVE19/PSMD9/KIF14/PSMD3/ALMS1	130
BP	GO:0034614	cellular response to reactive oxygen species	87/7096	168/18670	0.000183	0.00331	0.002468	KLF4/NQO1/FOS/KLF2/ANXA1/GCH1/PINK1/AIFM1/SOD1/STAT6/PLEKHA1/TNFAIP3/MTR/PSAP/TNF/EZH2/MPV17/AKR1C3/PKD2/RELA/PDK2/AXL/CYP1B1/HGF/MAP1LC3A/CD36/PRDX1/MAPK7/PCGF2/PRKCD/MAPK13/NCF1/NET1/ABL1/ADPRHL2/CRK/SIRT1/BMP7/TRPM2/OSER1/IL6/LRRK2/ETS1/MIR34A/SETX/SPHK1/HDAC2/MAPK8/MMP9/ZNF580/DNM2/PCNA/TPM1/MMP3/HNRNPD/FER/MAP3K5/KDM6B/UCP1/PXN/NFE2L2/IMPACT/DHFR/EGFR/TXN/TRAF2/PRKAA1/MDM2/MAPK1/NR4A3/ATP7A/CCNA2/AGAP3/MMP2/IL18RAP/PDE8A/PDCD10/SIGMAR1/MET/CHUK/ENDOG/MPO/ERCC6L2/PDGFD/FOXO3/MAPK9/ZNF277	87
BP	GO:0032984	protein-containing complex disassembly	157/7096	329/18670	0.000183	0.00331	0.002468	STMN1/MAP1S/MCOLN1/MRPS6/KLC1/CIB1/ATG14/MYC/LAMP2/NFE2/DVL2/TNF/IRAK3/C12orf65/GSK3B/MICAL1/MRPL35/TMOD3/LIMA1/MRPL45/TWF2/RDX/MAP1LC3A/CHCHD1/CFL2/CAPZA2/SYNJ1/SWAP70/INSR/MRPL40/MTIF2/MRPS30/MRPL34/STMN3/EIF2D/CAPG/MICAL2/IGF1R/TRMT112/MRPS16/CLN3/HMGA1/VPS33A/VTA1/FRAT2/ARHGEF2/CAPZA1/FRAT1/MRPS14/CHCHD10/MRPL54/DHX8/SH3BP1/MRPL44/SPTBN1/KIF2A/MRPL33/MAP1LC3C/SCAF8/GSPT2/MCTS1/CSNK1A1/DNAJC6/SETX/PHF23/SH3GL1/NAPA/AVIL/MRPL51/CHMP2A/KIF24/TSG101/CFL1/OXA1L/CKAP5/TRIOBP/IST1/ADRB2/GFM2/ETF1/ADD3/MTRF1L/PBRM1/ARID2/PLEK/MRPL49/CHMP1A/MRPL3/VPS4B/DDIT4/SEMA5A/FZD5/DMTN/ZMPSTE24/MRPL42/FZD1/DYRK3/DAP3/PPP1CA/CLASP2/LMOD3/PEX14/EIF5A/MRPS34/SCIN/DVL1/MAP1A/WNT1/MRPL4/GADD45GIP1/APEH/MRPS33/SMCR8/MTIF3/KIF2C/SCAF4/KATNB1/MRPL20/MRPL46/SMARCC2/MRPS18B/SPTA1/MRPL24/MRPL36/KIF5B/MRPS25/GABARAPL1/SPTBN2/CLEC16A/MRPS15/JMJD4/SET/MRPL48/VPS16/SUPT16H/MTRF1/SNAP29/VCP/AURKAIP1/NAV3/TRPV4/MRPL41/NCKAP5L/TTBK2/FZD2/MRPL2/SLN/MRPS2/SMARCC1/MRPS9/FGF13/CHMP1B/MRPL30/UPF1/MRPL1/MRRF/MRPS17	157
BP	GO:0022900	electron transport chain	95/7096	186/18670	0.0001831	0.00331	0.002468	NQO1/PINK1/C15orf48/POR/SRD5A1/AKR1B1/UQCRC2/STEAP4/SH3BGRL3/COX11/ADH5/ME1/UQCR11/DEGS1/NDUFA8/AIFM2/GSR/TXNRD1/AKR7A2/ETFA/DHRS3/NDUFC1/AKR7A3/ISCU/NDUFB11/AKR1A1/DHDH/CYB5A/RDH16/NCF2/NDUFS3/NCF1/LOXL2/NDUFA3/IDO1/ALDH2/NDUFA11/ETFDH/QDPR/ALDH4A1/UQCR10/COX7C/PPARGC1A/ALDH5A1/HAAO/COX7A2L/NDUFA4/IMMP2L/SLC25A12/GLRX3/COX4I2/NDUFA1/MYBBP1A/CYP1A2/WDR93/ETFB/COQ9/COA6/COX15/NDUFA10/CYBA/NDUFB1/CYBB/NDUFB5/UQCRQ/FDX1/NDUFS1/SLC25A13/NDUFB8/MAOB/DNAJC15/SURF1/CYB561/NDUFB6/NDUFB3/SDHA/NDUFS7/NDUFAF2/NDUFV2/ND4/SDHD/ME2/TAZ/SNCA/UQCRB/SLC25A22/NDUFB2/SDHAF2/COX6C/AOX1/PHGDH/NDUFS2/CIAPIN1/NDUFA7/COX7B	95
BP	GO:0060368	regulation of Fc receptor mediated stimulatory signaling pathway	11/7096	12/18670	0.0001861	0.003356	0.002502	APPL2/LYN/CSK/PLSCR1/PTPRC/CD226/RAP1A/CD47/RABGEF1/APPL1/PTPRJ	11
BP	GO:0070997	neuron death	165/7096	348/18670	0.0001902	0.003402	0.002536	NQO1/ITGAM/FOS/FYN/CX3CR1/NAMPT/GRN/ATG7/NR4A2/PINK1/GCLM/RILPL1/AIFM1/WNT5A/TSC1/SOD1/GPNMB/STAT3/CAPN2/GAPDH/CHP1/ALKBH1/SIAH1/FBXW7/LGMN/CEBPB/JAK2/EGR1/ADAM8/TNF/SLC7A11/HMOX1/SLC9A1/TNFRSF21/NUPR1/KRAS/APOE/GSK3B/BTG2/REL/ATF4/AXL/CHMP4B/STXBP1/ZNF746/FIS1/ARRB1/HIF1A/WFS1/PTK2B/HLA-F/CORO1A/IKBKG/MCL1/HTRA2/TLR4/ITSN1/FZD9/ADARB1/HSPA5/PARP2/CDK5/CASP3/HRAS/NMNAT1/ABL1/GCLC/CTSZ/CASP8/ZPR1/NCOA7/CLN3/CCL5/MAP3K12/SRPK2/LRP1/CREB1/CLU/SIRT1/TYROBP/EIF2S1/RAB29/LRRK2/DCC/CD200R1/G6PD/EGLN3/PPARGC1A/ATM/SNX6/BCL2L11/NRP1/BCL2/AIMP2/KDM2B/BAX/HDAC4/CASP2/CLCF1/SYNGAP1/AKT1S1/MAP3K11/UNC5B/PITX3/LIG4/DDIT4/MAP3K5/BHLHB9/F2R/FZD1/NSMF/CNTF/PPARA/FADD/TRAF2/WNT1/PSEN1/UBE2M/CNTFR/STAMBP/PSMC1/MAP2K4/BAD/EIF4G1/POU4F3/TGFB3/NLRP1/EPHB1/PIGT/IFNG/PPP1R13B/FAIM2/NR4A3/HYOU1/PIN1/CD34/HSP90AB1/RB1/LANCL1/SET/DIABLO/TERT/POLB/MTOR/RHOA/TYRO3/APP/SNCA/CX3CL1/BAG5/SIGMAR1/SSH1/PTPRZ1/SLC30A10/PICALM/ENDOG/DAXX/ERBB3/TLR6/KIF14/FOXO3/NTRK2/MEF2C/OXR1/GDF5	165
BP	GO:0071453	cellular response to oxygen levels	116/7096	234/18670	0.0001902	0.003402	0.002536	SLC8A1/EPAS1/KCNMB1/NAMPT/ATG7/PINK1/RBPJ/PGK1/AIFM1/LMNA/TSC1/ATP6AP1/TMBIM6/PTGS2/PSMB9/PPARD/GNB1/PMAIP1/PSMB8/SIRT4/MYC/RGCC/FAS/EGR1/PSMA5/ADAM8/PSMD11/HMOX1/SLC9A1/PSME1/SUV39H2/ATF4/HIGD1A/HIF1A/PSMB10/PSMA1/PSMA4/VEGFA/EGLN1/ATP6V1A/ENO1/PSMB1/PSMC4/S100B/PSMD13/PSMB3/SIRT1/BMP7/NDRG1/HIF1AN/EGLN3/PPARGC1A/CITED2/PSMB5/PSMD6/MIR34A/PSMC3/PLK3/COX4I2/SUV39H1/PSME3/BCL2/PSMC6/CPEB1/PDK1/UBC/CYBB/KCNK2/LPAR1/ARNT/STUB1/DNM1L/NFE2L2/DNMT3A/AQP3/MALAT1/ACAA2/PRKAA1/MDM2/PSMC1/CUL2/BAD/CHCHD2/PSMD8/RORA/TBL2/PSMA2/ATP7A/BACH1/CLCA1/HYOU1/OPRD1/CD34/CCNA2/CACNB3/PSMC5/TERT/PSMC2/PSMB2/PSMD4/MTOR/PICK1/RBX1/USP19/PSMD1/SLC8A3/ROCK2/ENDOG/PSMB4/UCN3/MGARP/PSMD9/PSMD3/CPEB2/FOXO3/MIR146A	116
BP	GO:0045582	positive regulation of T cell differentiation	48/7096	83/18670	0.0001903	0.003402	0.002536	PNP/NFKBIZ/LILRB2/ANXA1/EGR3/BCL6/NLRP3/DUSP10/IL4R/CBFB/PTPRC/ADAM8/CD74/IL7R/TGFB1/SOCS5/LILRB4/ZBTB1/ZBTB7B/NFKBID/RASGRP1/PIK3R6/IL7/TESPA1/HLA-G/CYLD/VNN1/IL12RB1/LGALS9/BTN2A2/ADA/HLX/IL18/AP3B1/TNFSF4/SART1/SOCS1/BAD/IFNG/IL12B/PRKCZ/CD80/RHOA/CD83/CCL19/MALT1/ZBTB16/IL23A	48
BP	GO:0032609	interferon-gamma production	62/7096	113/18670	0.0001941	0.003461	0.00258	CCR2/IL27RA/CLEC7A/SLC11A1/WNT5A/CEBPG/CD2/TNF/LILRB1/AXL/CD226/IL18R1/FAM49B/TCIRG1/IL20RB/TLR4/PTPN22/HLA-DPB1/HLA-DPA1/PDE4B/HRAS/ABL1/IL1B/RASGRP1/ISG15/HMGB1/IL1R1/ITK/BTN3A2/AZI2/SCGB1A1/PDCD1LG2/CD96/CD47/INHBA/IL12RB1/CD274/LGALS9/EBI3/PGLYRP4/FZD5/IRF8/C1QBP/IL18/FADD/CD276/TNFSF4/TLR8/BTN3A1/HAVCR2/TXK/TLR3/INHA/TNFRSF13C/IL12B/IL18RAP/CD244/CCR7/CD3E/NR1H4/IL23A/AVPR2	62
BP	GO:0030811	regulation of nucleotide catabolic process	47/7096	81/18670	0.0001983	0.003512	0.002619	IGF1/CBFA2T3/FBP1/STAT3/PFKFB3/NUP62/NUP160/NUP214/SLC2A6/P2RX7/NUPR1/PGAM1/EIF6/ZBTB7A/NUP85/HIF1A/SEH1L/INSR/NUP43/POM121/PFKFB4/PPARGC1A/SLC25A12/PRKAG2/MYOG/NCOR1/PFKFB1/NUP88/HDAC4/NUP107/DDIT4/PFKFB2/ARNT/PPARA/NUP93/PRKAA1/PSEN1/NUP205/NUP50/IFNG/PRKAG1/OGT/ESRRB/ZBTB20/APP/POM121C/AAAS	47
BP	GO:0048708	astrocyte differentiation	47/7096	81/18670	0.0001983	0.003512	0.002619	S100A8/FPR2/DLL1/GRN/STAT3/VIM/MAP2K1/LAMB2/TNF/KRAS/MIR142/LAMC3/ROR2/MBD1/TLR4/EIF2B5/BMP2/ABL1/IL1B/S100B/AGER/LDLR/LRP1/IL6ST/TTBK1/IL6/TAL1/BACE2/ID2/CLCF1/ROR1/DAB1/HES1/CNTF/IFNGR1/EGFR/PSEN1/MAPK1/TREM2/IFNG/PRPF19/NR2E1/APP/TSPAN2/PLP1/SMO/BIN1	47
BP	GO:0042542	response to hydrogen peroxide	77/7096	146/18670	0.0001986	0.003512	0.002619	KLF4/NQO1/SLC8A1/KLF2/FYN/DUSP1/ANXA1/LDHA/PINK1/TXNIP/AIFM1/SOD1/STAT6/CAPN2/PLEKHA1/TNFAIP3/STAT1/PSAP/EZH2/HMOX1/RELA/AXL/UBE3A/CYP1B1/HGF/MAP1LC3A/PTK2B/MAPK7/PCGF2/PRKCD/HBB/MAPK13/KPNA4/NET1/CAT/CASP3/ABL1/APTX/CRK/SIRT1/PPP1R15B/TRPM2/OSER1/IL6/LRRK2/ETS1/MIR34A/SETX/SPHK1/HDAC2/ZNF580/BCL2/PCNA/MAP3K5/KDM6B/ADA/NFE2L2/IMPACT/TXN/ADAM9/PRKAA1/MDM2/BAD/FOSL1/NR4A3/HP/GPX1/IL18RAP/PDE8A/PDCD10/SIGMAR1/MET/BAK1/ENDOG/PDGFD/FOXO3/ZNF277	77
BP	GO:0009394	2'-deoxyribonucleotide metabolic process	22/7096	31/18670	0.0002001	0.003522	0.002625	DGUOK/NEIL2/UNG/NUDT1/NT5C/ADK/CDADC1/GUK1/SAMHD1/CMPK2/TDG/TYMS/ADA/SHMT1/TBPL1/DCTD/DCTPP1/NT5M/DUT/NUDT16/MBD4/SMUG1	22
BP	GO:0050848	regulation of calcium-mediated signaling	55/7096	98/18670	0.0002003	0.003522	0.002625	IGF1/ATP2B4/BST1/GBP1/CAMTA1/CHP1/CIB1/TNF/SLC9A1/PKD2/GSK3B/CD22/PDK2/DYRK2/ITPR1/PTK2B/MYO5A/MAPK7/P2RY6/NRG1/RCAN3/CMKLR1/GSTO1/HINT1/HOMER3/DMD/LRRK2/TMBIM4/SRI/TRAT1/LMCD1/PRKACA/RCAN1/GPR143/PLEK/NFAT5/ADA/MYOZ1/CAMK2D/FHL2/TREM2/CASQ2/HRC/EFHB/CHP2/CD4/LACRT/SLA2/MTOR/P2RX2/CHERP/CCL4/CD3E/ERBB3/P2RX5	55
BP	GO:0042107	cytokine metabolic process	67/7096	124/18670	0.0002009	0.003523	0.002626	KLF4/CCR2/TLR1/CX3CR1/CLEC7A/BCL10/IRF7/ZFP36/IRF1/WNT5A/AZU1/STAT3/CEBPG/NLRP12/CEBPB/JAK2/PTPRC/EGR1/TNF/CD74/HMOX1/NFKB1/IL1RAP/LILRB1/TICAM1/RELA/NMI/PTAFR/HSPB1/TRAF6/TLR4/IL1B/AGER/UBE2J1/TYROBP/IL6/GLMN/MAPKAPK2/TRIB2/IL1A/LAG3/INHBA/PCSK5/EBI3/CYBB/IL18/CD276/CMA1/PSEN1/TLR8/SIGIRR/IFNG/CD4/TLR3/INHA/MAP2K5/LBP/TNFRSF13C/IL12B/ASB1/CD80/PRKCQ/APP/TIRAP/CD3E/TLR6/GHRL	67
BP	GO:0009314	response to radiation	207/7096	448/18670	0.0002051	0.00358	0.002669	CRIP1/JUNB/FOS/BMF/TRIM32/CDS1/NAMPT/DUSP1/ANXA1/CDKN2D/CDKN1A/NMT2/JUND/BHLHE40/RAD51AP1/PTGS2/FECH/GNB1/EYA3/SIK1/MYC/PER2/F11R/NABP1/PTPRC/EGR1/SLC7A11/CXCL10/ERCC6/TRIM13/KRAS/ERCC4/MAP3K4/HMGCR/CXCL12/ATF4/RELA/UBE4B/RAD1/TGFB1/HMGCS1/ALAD/ARRB1/HIF1A/GNAQ/PITPNM1/MAPK13/METTL3/USP28/RUVBL2/ZBTB1/HYAL2/UIMC1/TMEM161A/RBM4/DDB1/RBM4B/INTS7/TMEM109/NET1/HSPA5/CDK5/CAT/CASP3/HRAS/NPM1/PPM1D/XRCC5/IKBIP/PML/UBE2A/THBD/TNFRSF11A/METAP2/CREB1/PDE6G/CCL7/SIRT1/NPTN/TIPIN/CCND1/EIF2S1/MAP4K3/RHNO1/FBXL3/CRTC1/ATM/TNKS1BP1/POLH/XRCC4/AEN/ACTR5/TP53I13/NPHP4/PLK3/KAT5/POLG/MAPK8/BCL2/DNM2/PCNA/NEDD4/BAX/NOC2L/RGS14/ERCC1/ID2/RFWD3/ASNS/YY1/NR2E3/USP1/CDC25A/OPN3/SWI5/SYNGAP1/TSPYL5/CCR4/GRB2/CYBA/ST20/INTS3/HYAL3/LIG4/TICRR/DYNLRB1/ZMPSTE24/KDM4D/DTL/FKBPL/SDE2/FBXO4/IMPACT/C9orf116/E2F4/PPP1CC/PPP1CA/BRCA1/EGFR/TXN/ATR/DNMT3A/CLOCK/PRKAA1/FMR1/FANCG/HAMP/MDM2/SEMA5B/CHRNB2/DDB2/IFT20/GUCY2D/ERCC2/POLD1/XRCC6/DCLRE1C/RBL2/DCUN1D3/RAD9A/TOPBP1/FANCD2/CUL4B/PPP1CB/GRK4/CABP4/MEN1/DBH/IL12B/PER3/GPR52/EIF2AK4/POLB/GPX1/MTOR/KRT14/TRIAP1/BRSK1/APP/BRCC3/BAK1/TULP1/MGMT/ATP1A2/PAXIP1/CCDC66/CACNA2D4/RGR/UBE2B/CTNS/PDC/GJA10/CACNA1F/COPS3/PNKP/NUCKS1/SPIDR/FEN1/MBD4/NR2F6/GNA11/RP1/ZRANB3/OPN4/FIGNL1/SYNPO/ERCC8	207
BP	GO:1903509	liposaccharide metabolic process	61/7096	111/18670	0.0002053	0.00358	0.002669	FUCA1/ASAH1/HEXB/CTSA/GM2A/ESYT2/PIGV/PIGP/SUMF1/PSAP/PIGK/HEXA/SUMF2/SCCPDH/PIGN/GALC/PRKCD/B4GALT6/B3GNT5/CLN3/ST6GALNAC4/ST3GAL2/PIGF/GLA/PIGB/DPM1/GPAA1/ALDH5A1/CREM/ENPP7/PIGM/BAX/MPPE1/B4GALNT1/NAGA/PIGQ/GAL3ST4/CLN6/B4GALT5/PIGO/UGCG/ST8SIA4/CPTP/PIGH/STS/ARSA/ST6GALNAC5/PRKAA1/DPM3/CERK/PIGT/NEU1/ST6GALNAC3/SMPD1/ST6GALNAC6/SMPD2/PGAP3/ST8SIA1/ST3GAL5/GLTP/PGAP1	61
BP	GO:0010226	response to lithium ion	17/7096	22/18670	0.0002059	0.00358	0.002669	FABP4/PTGS2/PTK2B/ARL13B/EIF2B5/CEBPA/IGFBP2/ADCY7/ADCY1/XRCC4/MYOG/ID2/CDKN1B/LIG4/CALR/TPH2/ACTA1	17
BP	GO:0006110	regulation of glycolytic process	46/7096	79/18670	0.0002063	0.00358	0.002669	IGF1/CBFA2T3/FBP1/STAT3/PFKFB3/NUP62/NUP160/NUP214/SLC2A6/P2RX7/NUPR1/PGAM1/EIF6/ZBTB7A/NUP85/HIF1A/SEH1L/INSR/NUP43/POM121/PFKFB4/PPARGC1A/PRKAG2/MYOG/NCOR1/PFKFB1/NUP88/HDAC4/NUP107/DDIT4/PFKFB2/ARNT/PPARA/NUP93/PRKAA1/PSEN1/NUP205/NUP50/IFNG/PRKAG1/OGT/ESRRB/ZBTB20/APP/POM121C/AAAS	46
BP	GO:0010821	regulation of mitochondrion organization	93/7096	182/18670	0.0002083	0.003604	0.002687	IGF1/BMF/RAC2/VAT1/ATG7/PINK1/LMNA/TMEM135/SLC35F6/RNF41/HPS4/PMAIP1/SIRT4/FBXW7/YWHAH/SQSTM1/TMEM14A/GSK3B/PRELID1/CSNK2A2/CDC37/HIGD1A/MIEF1/HGF/FIS1/HIF1A/UBE2D3/DDHD1/MPV17L/HTRA2/FZD9/SFN/TNFSF10/OMA1/CASP8/RHOT2/ATG13/CHCHD10/CLU/SLC25A5/LRRK2/PLAUR/PPARGC1A/FLCN/RHOU/PDCD5/FNIP1/ARIH2/BCL2L11/VPS13D/MAPK8/ABLIM3/MMP9/TMEM102/BCL2/BAX/MICALL2/GZMB/MLLT11/UBL4B/LMAN1/USP30/YWHAQ/SREBF2/FZD5/DNM1L/VDAC1/HSPA1L/MUL1/ACAA2/PRKAA1/PID1/PARL/SH3GLB1/YWHAE/BAD/INF2/TREM2/PLA2G6/UBL5/PPP1R13B/BAP1/MOAP1/CLEC16A/WDR35/YWHAG/OPTN/LIG3/GPX1/TRIAP1/IAPP/BAK1/MGARP	93
BP	GO:0042063	gliogenesis	140/7096	290/18670	0.0002099	0.003606	0.002688	S100A8/FPR2/CCR2/CX3CR1/TLR2/HEXB/MPP5/DLL1/ANXA1/SUN2/GRN/LYN/SKI/CSK/AZU1/SOD1/STAT3/VIM/DUSP10/MBOAT7/RNF10/MAP2K1/LAMB2/SLC45A3/GSTP1/CERS2/TNF/EZH2/TNFRSF21/METTL14/KRAS/MIR142/RELA/TGFB1/PTK2B/LAMC3/ROR2/METTL3/NRG1/MBD1/B4GALT6/TLR4/EIF2B5/ASCL2/BMP2/DTX1/CDK5/ABL1/PAFAH1B1/NAB1/SRGAP2C/IL1B/CSPG4/S100B/AGER/HDAC11/LDLR/P2RY12/LRP1/CREB1/CLU/IL6ST/NDRG1/ZNF488/TTBK1/EGR2/ETV5/IL6/TAL1/IDH2/BACE2/PLAG1/DICER1/SYNE2/HDAC10/SRGAP2/HDAC2/DISC1/ID2/CDKN2C/CLCF1/ROR1/SPINT1/ADAM22/SH3TC2/LGI4/DAB1/B4GALT5/PITX3/PRMT5/MMP14/LPAR1/HES1/CDK5R2/CNTF/NFE2L1/PPP1CC/IFNGR1/EGFR/MXRA8/LAMA2/PSEN1/MAPK1/DNER/ERCC2/TREM2/EIF2B1/IFNG/EIF2B3/CNP/PRPF19/OLIG1/TERT/NR2E1/RELN/CSF1R/MTOR/RHOA/PICK1/APP/GPR183/RTN4/DAG1/CX3CL1/SOX4/TSPAN2/PTPRZ1/SLC8A3/EIF2B2/PLP1/PHGDH/SMO/KLF15/DAAM2/ERBB3/BIN1/P2RY1/NTRK2/POU3F1/MIR146A	140
BP	GO:0006643	membrane lipid metabolic process	104/7096	207/18670	0.0002106	0.003606	0.002688	FUCA1/ASAH1/HEXB/ALDH3A2/SGMS2/CTSA/PPP2CA/GM2A/ESYT2/CSNK1G2/PIGV/PIGP/SUMF1/MGST2/CERS2/PSAP/P2RX7/DEGS1/TNF/ELOVL5/PIGK/HEXA/FUT7/SUMF2/CLN8/SCCPDH/PIGN/CYP1B1/SGPL1/GALC/PRKCD/SGPP2/B4GALT6/CERS5/HTRA2/SERINC1/B3GNT5/SPTLC2/SAMD8/PLA2G15/CLN3/ST6GALNAC4/TECR/ST3GAL2/PIGF/VAPB/ELOVL7/GLA/CERS4/PIGB/DPM1/ARV1/GPAA1/ALDH5A1/CREM/ENPP7/ORMDL2/SPHK1/PIGM/P2RX1/SERINC3/ORMDL3/PRKD2/BAX/MPPE1/PPM1L/SGMS1/B4GALNT1/NAGA/PIGQ/GAL3ST4/CLN6/FUT6/B4GALT5/PIGO/UGCG/TEX2/ST8SIA4/CPTP/PIGH/STS/AGK/ARSA/ST6GALNAC5/ACER3/PRKAA1/DPM3/KDSR/PLA2G6/CERK/PIGT/NEU1/ST6GALNAC3/SMPD1/ST6GALNAC6/ELOVL6/SMPD2/SERINC2/PGAP3/ST8SIA1/ST3GAL5/GLTP/PGAP1/DEGS2	104
BP	GO:0071456	cellular response to hypoxia	104/7096	207/18670	0.0002106	0.003606	0.002688	SLC8A1/EPAS1/KCNMB1/PINK1/RBPJ/PGK1/LMNA/TMBIM6/PTGS2/PSMB9/PPARD/GNB1/PMAIP1/PSMB8/SIRT4/MYC/RGCC/EGR1/PSMA5/ADAM8/PSMD11/HMOX1/SLC9A1/PSME1/SUV39H2/HIGD1A/HIF1A/PSMB10/PSMA1/PSMA4/VEGFA/EGLN1/ENO1/PSMB1/PSMC4/S100B/PSMD13/PSMB3/SIRT1/BMP7/NDRG1/HIF1AN/EGLN3/PPARGC1A/CITED2/PSMB5/PSMD6/MIR34A/PSMC3/PLK3/COX4I2/SUV39H1/PSME3/BCL2/PSMC6/CPEB1/PDK1/UBC/CYBB/KCNK2/ARNT/STUB1/NFE2L2/DNMT3A/AQP3/MALAT1/ACAA2/PRKAA1/MDM2/PSMC1/CUL2/BAD/CHCHD2/PSMD8/RORA/TBL2/PSMA2/ATP7A/BACH1/CLCA1/HYOU1/OPRD1/CD34/CCNA2/PSMC5/TERT/PSMC2/PSMB2/PSMD4/MTOR/RBX1/USP19/PSMD1/SLC8A3/ROCK2/ENDOG/PSMB4/UCN3/MGARP/PSMD9/PSMD3/CPEB2/FOXO3/MIR146A	104
BP	GO:0032755	positive regulation of interleukin-6 production	54/7096	96/18670	0.0002106	0.003606	0.002688	MYD88/NOD2/TLR1/TLR2/LILRB2/CLEC7A/WNT5A/STAT3/LILRA5/MBP/LILRA2/P2RX7/TNF/CD74/IL1RAP/TICAM1/PTAFR/CD36/MAPK13/TRAF6/HYAL2/TLR4/DDX58/IL1B/AIF1/AGER/DHX9/ARHGEF2/HMGB1/IL1RN/TYROBP/MAVS/SIGLEC16/IL6/IFIH1/ADORA2B/LGALS9/CYBA/RAB7B/F2R/TNFSF4/TLR8/TSLP/TLR3/LBP/ZBTB20/TRPV4/APP/TIRAP/AKIRIN2/HMGB4/TLR6/IL17RC/IL37	54
BP	GO:0051017	actin filament bundle assembly	80/7096	153/18670	0.0002178	0.003719	0.002773	S100A10/EZR/PTGER4/DPYSL3/PLS1/STMN1/FHOD1/TSC1/ARAP1/SORBS3/ITGB5/NEDD9/FLNA/RHOC/S1PR1/ACTN4/RGCC/SPIRE1/SLC9A1/ARHGEF10L/RND3/LIMA1/EVL/RDX/PFN1/ARRB1/PAK1/MARCKS/PHACTR1/PTK2B/SWAP70/SRF/ACTN1/BAIAP2/ABL1/AIF1/PPM1F/MKKS/RAC1/CORO1B/ARHGAP6/BBS4/LIMCH1/ZYX/LCP1/NRP1/FSCN3/TPM1/INPP5K/CD47/PLS3/ADD3/PLEK/SHANK1/RHOF/LPAR1/DMTN/PXN/CLASP2/HSP90B1/FSCN1/APOA1/TGFB3/SYNPO2L/TACSTD2/TMEFF2/MTOR/RHOA/CX3CL1/ITGB1BP1/MET/SHROOM1/ESPNL/WAS/ROCK2/ASAP3/SHANK3/SERPINF2/ALMS1/SYNPO	80
BP	GO:0050867	positive regulation of cell activation	184/7096	394/18670	0.0002296	0.00391	0.002915	IGF1/ITGAM/NOD2/PNP/CCR2/FYN/NFKBIZ/PTPN6/LILRB2/ANXA1/CDKN1A/BST1/CLEC7A/BCL10/LYN/MAD2L2/CD55/TNIP2/WNT5A/CSK/CLEC4D/EGR3/STAT6/LILRA5/TNFRSF14/BCL6/NLRP3/DUSP10/CD40/MIF/CD2/CTSC/LILRA2/IL4R/CBFB/JAK2/MAP3K8/PTPRC/IL15/ADAM8/LAMP1/CD74/CD320/LILRB1/TICAM1/DPP4/MIR142/IL7R/AXL/DOCK8/CD226/TGFB1/STXBP1/CCDC88B/PTAFR/PAK1/SOCS5/LEP/TNFSF13B/FAM49B/HLA-F/CORO1A/LILRB4/TRAF6/ZBTB1/FLT3LG/TLR4/ZBTB7B/FGR/CEBPA/HLA-DPB1/HLA-DPA1/HLA-E/NCK1/CD209/SLC39A10/NFKBID/PAK2/IL1B/AIF1/SIRPB1/AGER/CCL5/RASGRP1/RASAL3/PIK3R6/HLA-DMB/ICOSLG/HMGB1/EFNB1/IGFBP2/IL7/TYROBP/IL6ST/TESPA1/HLA-G/RAC1/TOX/TTBK1/TRBC1/IL6/IRS2/LCK/CYLD/LRRK2/FLOT2/CTLA4/VNN1/PDCD1LG2/ADORA2B/MLH1/BCL2/BLOC1S3/NFATC2/CD47/CLCF1/LGALS1/PPP2R3C/CD1D/IL12RB1/GRB2/CD274/PLEK/LGALS9/EBI3/ICOS/BTN2A2/MMP14/DMTN/HES1/ADA/HLX/VAV1/IL18/FADD/AP3B1/CD276/TFRC/TNFSF4/SART1/AP1G1/CHRNB2/SOCS1/SIRPG/BAD/TREM2/TNFRSF4/CAPN3/HAVCR2/TSLP/IFNG/SPTA1/NR4A3/CD5/EXOSC3/PCID2/CD4/SNX4/LBP/TNFRSF13C/IL12B/PRKCZ/CD80/TBX21/PRKCQ/RHOA/GPR183/CD83/EXOSC6/CCL19/MALT1/TIRAP/ZBTB16/CCR7/PAXIP1/CD3E/ATAD5/PDCD1/CD24/IL23A/TLR6/IGHD/MEF2C/ZNF335	184
BP	GO:0010389	regulation of G2/M transition of mitotic cell cycle	99/7096	196/18670	0.0002302	0.00391	0.002915	PRKAR2B/TUBA1A/NINL/PSMB9/CUL1/RAB11A/PSMB8/RNASEH2B/HUS1B/ODF2/PSMA5/PSMD11/HAUS8/PSME1/GPR132/CNTRL/CDK4/TAOK3/SIN3A/CEP164/ZNF830/PSMB10/PCM1/MTA3/PSMA1/PSMA4/CSNK1D/CEP131/DBF4B/SYF2/SFI1/PAFAH1B1/RAD51B/CDK5RAP2/PSMB1/PSMC4/DONSON/CEP76/PSMD13/MAPRE1/PSMB3/CCND1/PSMB5/PSMD6/ATM/CSNK1E/HAUS2/PSMC3/PSME3/RAD17/PSMC6/PRKACA/CKAP5/DCTN2/FHL1/CDC25A/CEP152/TUBA4A/VPS4B/FOXO4/TICRR/MIIP/DTL/CEP63/BRCA1/CEP57/RCC2/CETN2/HAUS5/TUBB4A/HAUS1/YWHAE/PSMC1/CLSPN/PSMD8/PSMA2/FBXL7/TOPBP1/FGFR1OP/YWHAG/PSMC5/PKIA/PSMC2/PSMB2/PSMD4/AURKA/BRSK1/APP/RBX1/CEP78/CCNB3/PSMD1/WNT10B/PSMB4/ZFYVE19/PSMD9/KIF14/PSMD3/ALMS1	99
BP	GO:0048193	Golgi vesicle transport	173/7096	368/18670	0.0002313	0.003919	0.002921	SERPINA1/F5/SNX1/CD55/CSK/MCFD2/PROS1/GGA2/LMAN2L/KLC1/KLHL12/DYNC1LI1/CTSC/SEC22B/RNF139/TRIM23/VAMP5/BCAP31/LAMP1/CD59/SYS1/EXOC6B/RAB31/VPS13A/SCAMP2/ANKRD28/KIF3B/EXOC1/GOLGB1/KIFAP3/SAR1B/TRAPPC6A/ARF4/MYO5A/CAPZA2/DYNLL2/COG8/CSNK1D/PPP6R1/CENPE/BICD2/CNIH3/COPE/TRAPPC5/ARF5/GOPC/VAMP3/ERGIC1/SCAMP1/DNAJC28/CTSZ/ARFGAP3/C16orf70/TMED10/RP2/CREB3L2/CNST/CAPZA1/SEC22A/LMF1/KIF4A/WIPI1/BET1/BBS2/VAPB/RAB8A/RAB43/RAB33B/PREPL/SPTBN1/KIF2A/GOSR2/LRRK2/GOSR1/CNIH4/TEX261/TAPBP/IER3IP1/STX5/KIF16B/SAR1A/ARF1/PPP6C/KDELR3/TRAPPC6B/TRAPPC9/GOLPH3L/NAPA/DNM2/VPS51/TBC1D20/MPPE1/COPG2/GOLGA5/COL7A1/CCDC93/COG4/DCTN2/COPA/RANGRF/KDELR2/KIF13A/VPS52/LMAN1/ARL1/NKD2/VTI1A/ZW10/PEF1/COG6/ARFRP1/RAB7B/SEC22C/NAPG/YKT6/AP2A1/STX18/TMED5/COMMD1/INSIG1/SEC23IP/RAB8B/RABEP1/ARCN1/TRAPPC2L/AP1G1/CEP19/TRAPPC3/TMED4/KIF2C/VTI1B/COG2/EXOC4/COG1/SPTA1/LLGL1/COPZ2/HYOU1/EHD3/SCFD1/SPTBN2/BCAP29/YIF1B/YIF1A/COG7/DYNC1LI2/OPTN/KLC2/NRBP1/TRAPPC8/VCP/KIF1C/PICK1/RAB33A/RER1/GOLGA3/ERGIC2/DCTN6/DCTN5/NBAS/PREB/SEC24A/CCDC91/ARF3/ARFGAP1/RAB26/F9/PGAP1/MACF1/TRAPPC11/EXOC2/SEC31B/SEC16B	173
BP	GO:0006888	ER to Golgi vesicle-mediated transport	106/7096	212/18670	0.0002328	0.003924	0.002925	SERPINA1/F5/CD55/MCFD2/PROS1/LMAN2L/KLHL12/DYNC1LI1/CTSC/SEC22B/RNF139/BCAP31/CD59/ANKRD28/GOLGB1/SAR1B/TRAPPC6A/ARF4/CAPZA2/DYNLL2/COG8/CSNK1D/PPP6R1/CNIH3/COPE/TRAPPC5/GOPC/ERGIC1/CTSZ/ARFGAP3/TMED10/CREB3L2/CAPZA1/SEC22A/LMF1/BET1/VAPB/RAB43/RAB33B/SPTBN1/GOSR2/LRRK2/GOSR1/CNIH4/TEX261/IER3IP1/STX5/SAR1A/ARF1/PPP6C/KDELR3/TRAPPC6B/TRAPPC9/NAPA/TBC1D20/MPPE1/COPG2/COL7A1/COG4/DCTN2/COPA/RANGRF/KDELR2/LMAN1/VTI1A/ZW10/PEF1/COG6/SEC22C/YKT6/STX18/TMED5/INSIG1/SEC23IP/ARCN1/TRAPPC2L/TRAPPC3/TMED4/VTI1B/COG2/COG1/SPTA1/COPZ2/HYOU1/SCFD1/SPTBN2/BCAP29/YIF1B/YIF1A/COG7/DYNC1LI2/NRBP1/TRAPPC8/VCP/RAB33A/ERGIC2/DCTN6/DCTN5/PREB/SEC24A/ARFGAP1/F9/PGAP1/TRAPPC11/SEC31B/SEC16B	106
BP	GO:0071219	cellular response to molecule of bacterial origin	106/7096	212/18670	0.0002328	0.003924	0.002925	NOD2/TLR1/CX3CR1/TLR2/LILRB2/BCL10/SBNO2/LYN/CD55/ZFP36/TNIP2/WNT5A/VIM/HCK/CAPN2/NLRP3/PPARD/TFPI/TNFAIP3/MIF/LY96/LY86/PPBP/LILRA2/CXCL9/CEBPB/SCARB1/GSTP1/CXCL11/TNF/PAF1/NFKBIA/CXCL10/NFKB1/LILRB1/PLAA/TICAM1/RELA/AXL/CDK4/TGFB1/PTAFR/CD36/NR1H2/TRAF6/CXCL13/TLR4/PTPN22/PDE4B/CACTIN/ABL1/NFKBIB/ABCA1/IL1B/CCL5/HMGB1/CMPK2/IL1RN/IL6/PPARGC1A/CCR5/BCR/PDCD1LG2/AKAP8/MAPK8/SERPINE1/HMGB2/NR1H3/SGMS1/TNIP3/CASP1/PRPF8/CD274/FZD5/IRF8/IL18/ADAM9/TNFSF4/HAMP/MAPK1/SIGIRR/TREM2/HAVCR2/LACRT/CTSG/LBP/IL12B/MTDH/CD80/HDAC5/PLSCR4/RHOA/CDC73/CX3CL1/PDCD4/MALT1/TIRAP/NR1H4/PRKCA/TLR6/CXCL6/MEF2C/UPF1/SASH1/IL37/MIR146A	106
BP	GO:0002696	positive regulation of leukocyte activation	178/7096	380/18670	0.0002381	0.003998	0.002981	IGF1/ITGAM/NOD2/PNP/CCR2/FYN/NFKBIZ/PTPN6/LILRB2/ANXA1/CDKN1A/BST1/CLEC7A/BCL10/LYN/MAD2L2/CD55/TNIP2/WNT5A/CSK/CLEC4D/EGR3/STAT6/TNFRSF14/BCL6/NLRP3/DUSP10/CD40/MIF/CD2/CTSC/IL4R/CBFB/MAP3K8/PTPRC/IL15/ADAM8/LAMP1/CD74/CD320/LILRB1/TICAM1/DPP4/MIR142/IL7R/AXL/DOCK8/CD226/TGFB1/STXBP1/CCDC88B/PTAFR/PAK1/SOCS5/LEP/TNFSF13B/FAM49B/HLA-F/CORO1A/LILRB4/TRAF6/ZBTB1/FLT3LG/TLR4/ZBTB7B/FGR/CEBPA/HLA-DPB1/HLA-DPA1/HLA-E/NCK1/CD209/SLC39A10/NFKBID/PAK2/IL1B/AIF1/SIRPB1/AGER/CCL5/RASGRP1/RASAL3/PIK3R6/HLA-DMB/ICOSLG/HMGB1/EFNB1/IGFBP2/IL7/TYROBP/IL6ST/TESPA1/HLA-G/RAC1/TOX/TTBK1/TRBC1/IL6/IRS2/LCK/CYLD/LRRK2/FLOT2/CTLA4/VNN1/PDCD1LG2/ADORA2B/MLH1/BCL2/BLOC1S3/NFATC2/CD47/CLCF1/LGALS1/PPP2R3C/CD1D/IL12RB1/GRB2/CD274/LGALS9/EBI3/ICOS/BTN2A2/MMP14/HES1/ADA/HLX/VAV1/IL18/FADD/AP3B1/CD276/TFRC/TNFSF4/SART1/AP1G1/CHRNB2/SOCS1/SIRPG/BAD/TREM2/TNFRSF4/HAVCR2/TSLP/IFNG/SPTA1/NR4A3/CD5/EXOSC3/PCID2/CD4/SNX4/LBP/TNFRSF13C/IL12B/PRKCZ/CD80/TBX21/PRKCQ/RHOA/GPR183/CD83/EXOSC6/CCL19/MALT1/TIRAP/ZBTB16/CCR7/PAXIP1/CD3E/ATAD5/PDCD1/CD24/IL23A/TLR6/IGHD/MEF2C/ZNF335	178
BP	GO:0032735	positive regulation of interleukin-12 production	24/7096	35/18670	0.0002385	0.003998	0.002981	TLR2/CLEC7A/IRF1/CD40/RELA/CD36/TRAF6/TLR4/IDO1/AGER/HMGB1/HLA-G/LGALS9/PLCB1/IRF8/TNFSF4/IFNG/MAPK11/TLR3/IL12B/CCL19/TIRAP/CCR7/IL23A	24
BP	GO:0030808	regulation of nucleotide biosynthetic process	64/7096	118/18670	0.0002395	0.004004	0.002985	IGF1/CBFA2T3/PDK4/PINK1/FBP1/STAT3/PFKFB3/NUP62/NUP160/NUP214/SLC2A6/P2RX7/NUPR1/PGAM1/PDK2/EIF6/ZBTB7A/NUP85/HIF1A/SEH1L/INSR/NUP43/ENO1/DNAJC30/GSTZ1/POM121/PFKFB4/PPARGC1A/FLCN/SLC25A12/PRKAG2/MYOG/NCOR1/ADORA2B/PFKFB1/NUP88/HDAC4/NUP107/PDK1/DDIT4/PFKFB2/ARNT/PDP2/PPARA/NUP93/PRKAA1/PSEN1/NUP205/PID1/TREM2/NUP50/IFNG/PRKAG1/OGT/PDP1/ESRRB/ZBTB20/VCP/TAZ/APP/SNCA/PDPR/POM121C/AAAS	64
BP	GO:0044106	cellular amine metabolic process	69/7096	129/18670	0.0002423	0.00404	0.003012	NQO1/ITGAM/SMS/ATP2B4/NR4A2/OAZ2/PSMB9/PSMB8/GDE1/SIRT4/ALDH7A1/PSMA5/PSMD11/SLC7A11/HNMT/SAT1/PSME1/SLC7A7/PSMB10/PSMA1/PNKD/PSMA4/NAPEPLD/OAZ3/MAOA/IDO1/PSMB1/ODC1/PSMC4/PSMD13/PSMB3/KYNU/HAAO/PSMB5/PSMD6/HDAC10/PSMC3/PSME3/PSMC6/BHMT/AZIN1/CHKA/TPH2/IDO2/MAOB/CHRNB2/PSMC1/SRM/PSMD8/PSMA2/ATP7A/SULT1B1/DBH/PSMC5/PSMC2/PSMB2/PSMD4/SNCA/AZIN2/ATCAY/CHDH/AGMAT/PSMD1/DHPS/PSMB4/TDO2/NR1H4/PSMD9/PSMD3	69
BP	GO:0006520	cellular amino acid metabolic process	172/7096	366/18670	0.0002459	0.00408	0.003042	NQO1/SMS/ASRGL1/ATP2B4/SEPHS2/GCLM/ENOSF1/HIBADH/ARG2/PARS2/OAZ2/PSMB9/IL4I1/PCYOX1/HMGCL/PPA1/PSMB8/ADI1/SIRT4/PSPH/AHCY/MTR/ALDH7A1/PHYKPL/BCKDK/SEPSECS/PSMA5/PSMD11/SLC7A11/PEPD/NARS2/ALDH6A1/PCBD1/HAL/DDAH2/HNMT/PSME1/FAH/ALDH18A1/ATF4/NFS1/GMPS/SLC7A7/CRTAP/EEF1E1/APIP/AUH/PSMB10/PSMA1/PSMA4/SLC7A6/DBT/NAGS/AIMP1/OAZ3/EGLN1/CTPS2/MTRR/IDO1/GCLC/DPYD/LARS2/ENOPH1/PSMB1/GSTZ1/ODC1/PSMC4/CLN3/PPA2/AASDH/QDPR/PSMD13/OGDH/GATM/ALDH4A1/ASNSD1/PSMB3/DALRD3/ACADSB/GLUD1/PTS/PCYOX1L/PLOD1/DAO/EGLN3/ADHFE1/ALDH5A1/MCCC1/KYNU/HAAO/PSMB5/PSMD6/MTAP/BPHL/PSMC3/SLC25A12/IARS2/SHMT2/GLUD2/TST/SERINC3/PSME3/SLC7A8/AIMP2/MPST/PSMC6/HSD17B10/ALDH8A1/CTH/ASNS/BHMT/PLOD2/GSS/GAMT/PPAT/AZIN1/GLS/GOT2/AHCYL2/AGXT2/SHMT1/AHCYL1/DCT/AASDHPPT/TPH2/IDO2/AMT/GFPT1/MARS2/GGT5/PSMC1/HARS2/SRR/FPGS/BCKDHB/PSMD8/CTPS1/CAD/PSMA2/AMDHD1/ATP7A/SLC7A2/BCAT2/YARS2/DARS2/QRSL1/PSMC5/BCKDHA/PSMC2/PSMB2/PSMD4/GFPT2/HYKK/SLC25A32/AZIN2/ATCAY/AGMAT/HMGCLL1/PSMD1/CTNS/PHGDH/PSMB4/P4HA1/TDO2/NR1H4/AARS2/MAT1A/PSMD9/PSMD3/CKMT2/WARS2/PIPOX	172
BP	GO:0043574	peroxisomal transport	41/7096	69/18670	0.0002465	0.00408	0.003042	HMGCL/PEX12/ACAA1/PHYH/SCP2/MPV17/PEX16/ECH1/UBE2D3/UBE2D2/USP9X/CAT/AGPS/ACOX1/ECI2/SLC27A2/HSD17B4/IDH1/ACOX2/DAO/DECR2/MLYCD/NUDT19/PEX13/TYSND1/PEX3/UBC/PEX19/EHHADH/RAB8B/NUDT7/PEX14/ACOX3/GNPAT/CROT/ABCD1/ZFAND6/HACL1/HAO1/ACOT8/PIPOX	41
BP	GO:0051865	protein autoubiquitination	41/7096	69/18670	0.0002465	0.00408	0.003042	KLHL24/RNF41/SH3RF1/RNF10/UHRF1/TRIM13/RNF19B/TRIM68/UBE4B/TRIM37/UBE3A/UBE2D3/TRAF6/RNF13/UBE2D2/RNF11/RNF146/UBE2A/LRRK2/RNF213/RNF115/UHRF2/RNFT1/DTX3L/TRIM21/CNOT4/SH3RF3/STUB1/BRCA1/WWP2/TRAF2/BFAR/MDM2/DDB2/RNF4/RNF185/RNF208/TRIM58/UBE2B/SASH1/ERCC8	41
BP	GO:0016311	dephosphorylation	219/7096	478/18670	0.0002493	0.004114	0.003067	PTPN6/LILRB2/ACP5/DUSP1/NANP/DUSP6/PINK1/FBP1/PPP2CA/DUSP5/TSC1/CAMTA1/ATP1A1/PTPN2/PFKFB3/PPP1R15A/CHP1/NT5DC1/MGAT5/EYA3/DUSP10/SSH2/PPM1H/PALD1/HDHD2/PSPH/ACPP/WDR81/DUSP7/JAK2/PTPRC/SHOC2/TNF/PTP4A1/IMPAD1/PTPMT1/NTPCR/INPP1/GSK3B/PTPRO/PPP4C/CABIN1/PTPN13/DUSP3/SACM1L/PPP4R2/TGFB1/PPP3CB/PHACTR2/PPP2R3A/DUSP18/PHACTR1/PPP1R16A/NT5C/PPP1R26/PPP1R3E/SYNJ1/SWAP70/PPP6R1/PRKCD/PTPN7/PPP1R3D/SPOCD1/SGPP2/DAPP1/PPP1R14A/DUSP2/ELFN1/PTPN22/PPP1R37/BMP2/NCK1/FIG4/RCAN3/PPP1R2/PPM1D/SFI1/SLC39A10/PPP1R14B/ENOPH1/APTX/PHOSPHO2/PPA2/PTPN4/CNST/SEMA4D/SYMPK/SYNJ2/PPM1F/PPP1R15B/PPP1R16B/MFHAS1/DUSP19/CTDP1/PPM1M/OCRL/LCK/CDH5/RPRD1B/PFKFB4/DUSP12/PPP2R5C/CD2BP2/ANKLE2/RNGTT/DUSP14/DNAJC6/PPP6C/DUSP4/DUSP23/LMTK3/CTDSPL/PPM1N/ZFYVE1/SBF1/TAB1/PFKFB1/BCL2/GNAI2/PPP2R2D/MTMR4/BOD1L1/PPP2R2B/INPP5K/IMPA2/MTMR6/ELFN2/CTDSP1/ALPP/PPP1R3B/PPM1L/RCAN1/CDC25A/ITGA2/PPP2R3C/ACP6/MTMR2/CD300A/PPP4R1/INPP5F/PLEK/PPP1R36/PTPRN2/PPM1J/PFKFB2/ZCCHC9/PPP1R7/MYOZ1/NSMF/SPRED1/PPP1CC/PPP1CA/PPP2R1B/PDP2/EIF2AK2/PPP1R11/CTDSP2/HSP90B1/MTMR3/DLGAP5/PTPDC1/THTPA/YWHAE/EYA4/MINPP1/SYTL2/PPEF2/IGBP1/LMTK2/IFNG/RPAP2/SSH3/CHP2/PDP1/MTMR9/MASTL/PIN1/B3GAT3/PPP1CB/SMPD1/PPP1R14D/HSP90AB1/PPP2R5B/PHLPP2/CILP/PHACTR4/SET/POLB/CD33/PTPRH/CDCA2/MTOR/NT5C3A/DUSP13/NT5M/CILP2/SSH1/PTPRZ1/SDHAF2/TIMM50/LHPP/MYH3/PPM1G/NUDT16/ROCK2/CCDC8/INPPL1/PNKP/UBASH3A/G6PC/BOD1/CTDSPL2/PPP2R2C/MEF2C/INPP5A/PTPRM/PTPRJ/IMPA1/PHPT1	219
BP	GO:0043467	regulation of generation of precursor metabolites and energy	82/7096	158/18670	0.0002517	0.004144	0.003089	IGF1/CBFA2T3/PINK1/FBP1/PGK1/STAT3/PFKFB3/NUP62/NUP160/NUP214/SLC2A6/P2RX7/NUPR1/GSK3B/PRELID1/PGAM1/DYRK2/EIF6/ZBTB7A/NUP85/HIF1A/ISCU/SEH1L/PPP1R3E/INSR/PPP1R3D/NUP43/DNAJC30/UQCC2/POM121/CHCHD10/IRS2/PFKFB4/PPARGC1A/FLCN/COX7A2L/SLC25A12/SHMT2/PRKAG2/MYOG/NCOR1/KHK/PFKFB1/NUP88/INPP5K/HDAC4/PPP1R3B/NUP107/PPP1R3F/CISD1/NOA1/DDIT4/PGK2/PFKFB2/ARNT/PPP1CA/SLC25A33/PPARA/NUP93/PRKAA1/PSEN1/DNAJC15/NUP205/NUP50/IFNG/PRKAG1/OGT/ATP7A/PPP1CB/ESRRB/ZBTB20/VCP/MTOR/RHOA/TRPV4/APP/SNCA/ABCD1/PNPT1/POM121C/AAAS/NKX1-1	82
BP	GO:0046034	ATP metabolic process	146/7096	305/18670	0.0002532	0.004147	0.003092	IGF1/CBFA2T3/HK3/LDHA/PINK1/FBP1/PGK1/VPS9D1/STAT3/PFKFB3/NUP62/NUP160/PFKM/UQCRC2/PFKP/GAPDH/SLC25A25/NUP214/SLC2A6/P2RX7/UQCR11/NDUFA8/NUPR1/PGAM1/AK2/PKM/GALK1/EIF6/TPI1/ZBTB7A/NDUFC1/TGFB1/NUP85/CLPX/HIF1A/ISCU/SEH1L/NDUFB11/INSR/ALDOC/NDUFS3/GUK1/NUP43/NDUFA3/NMNAT1/ATP6V1A/ENO1/DNAJC30/ALDOA/UQCC2/NDUFA11/PARG/POM121/OGDH/CHCHD10/UQCR10/COX7C/GPI/ATP6V1B2/PFKFB4/PPARGC1A/FLCN/COX7A2L/DHTKD1/NDUFA4/SLC25A12/SHMT2/LDHC/PRKAG2/MYOG/NCOR1/COX4I2/NDUFA1/PFKFB1/NUP88/HDAC4/ATP1B1/NUDT5/TEFM/COQ9/NUP107/COA6/COX15/NDUFA10/FOXK2/NDUFB1/DDIT4/NDUFB5/UQCRQ/PGK2/PFKFB2/ARNT/DNM1L/NDUFS1/SLC25A33/PPARA/NUP93/SLC25A13/NDUFB8/PRKAA1/PSEN1/DNAJC15/NUP205/ENO2/PID1/SURF1/NDUFB6/BAD/SLC4A1/TREM2/NUP50/IFNG/PRKAG1/OGT/ATP7A/NDUFB3/SDHA/ESRRB/ZBTB20/VCP/NDUFS7/ADPGK/NDUFV2/ND4/SDHD/RHOA/TAZ/APP/SNCA/UQCRB/ATP6V1B1/AMPD3/ABCD1/NDUFB2/SDHAF2/MYH3/COX6C/ATP1A2/PFKL/CTNS/NDUFS2/POM121C/AAAS/FIGNL1/NDUFA7/COX7B	146
BP	GO:0045730	respiratory burst	25/7096	37/18670	0.0002537	0.004147	0.003092	RAC2/CLEC7A/GRN/CD55/SLC11A1/HCK/DUSP10/CAMK1D/PGAM1/NCF4/INSR/NCF2/NCF1/RAC1/NOXA1/BCR/RPS19/PIK3CD/CYBA/CYBB/PIK3CG/LBP/MPO/SLAMF8/CD24	25
BP	GO:0002220	innate immune response activating cell surface receptor signaling pathway	63/7096	116/18670	0.0002538	0.004147	0.003092	FYN/ICAM2/BCL10/LYN/ICAM3/CLEC4D/FCN1/PSMB9/CUL1/CLEC4E/PSMB8/LILRA2/PSMA5/PSMD11/PRKACB/NFKB1/KRAS/PSME1/RELA/FFAR2/PAK1/PSMB10/PSMA1/PSMA4/PRKCD/TAB3/TRAF6/IKBKG/CD209/HRAS/RELB/PSMB1/PAK2/PSMC4/PLCG2/PSMD13/MUC2/RAF1/PSMB3/PSMB5/PSMD6/MUC1/PSMC3/TAB1/PSME3/PSMC6/PRKACA/NRAS/MUC6/PSMC1/PSMD8/PSMA2/MUCL1/PSMC5/PSMC2/PSMB2/PSMD4/MALT1/CHUK/PSMD1/PSMB4/PSMD9/PSMD3	63
BP	GO:0006767	water-soluble vitamin metabolic process	50/7096	88/18670	0.0002562	0.004155	0.003098	ACP5/SLC19A2/MMADHC/MTHFD2/SLC23A2/SLC25A19/PANK2/ACPP/ABCD4/MTR/FOLR2/SLC2A3/CD320/BTD/AKR1A1/CYB5A/MTRR/GCLC/GSTO1/RFK/TPK1/PRSS3/MCCC1/KYNU/HAAO/PDZD11/SHMT2/VNN1/MMAB/PCCB/MMACHC/CTRB2/SLC46A1/SLC5A6/CYB5R3/FLAD1/LMBRD1/SHMT1/DHFR/AASDHPPT/CLYBL/THTPA/TCN1/FPGS/CTRC/ALDH1L1/PC/SLC25A32/VNN3/AOX1	50
BP	GO:1903725	regulation of phospholipid metabolic process	50/7096	88/18670	0.0002562	0.004155	0.003098	KLF4/FPR2/HTR2B/NOD2/SLC27A1/SOCS3/LYN/FLT1/CAPN2/WDR91/ATG14/WDR81/APOC1/SCARB1/CISH/PIK3R3/TGFB1/SOCS5/PTK2B/PRKCD/PIK3IP1/FLT3/SOCS6/FGR/LDLR/PIK3R6/P2RY12/IDH1/FABP3/SOCS7/PDGFB/EPHA8/RAB38/GNB3/PTK2/ARF1/MTMR4/MTMR2/PDGFA/MTMR3/SOCS1/MTMR9/SLA2/TAZ/CCL19/LPCAT1/CCKBR/CCR7/SOCS2/NR1H4	50
BP	GO:0044242	cellular lipid catabolic process	108/7096	217/18670	0.0002562	0.004155	0.003098	FUCA1/ASAH1/HEXB/ALDH3A2/HADHB/FABP4/ENPP2/GM2A/PPARD/HADH/ACAA1/GDE1/ABHD6/ABHD12/GPCPD1/PHYH/APOC1/SCARB1/MGST2/PSAP/MGLL/SCP2/AKR1C3/APOE/PNPLA6/PNPLA3/ETFA/CPT2/CYP1B1/AUH/ABCD3/SGPL1/GALC/PCK2/LEP/ECH1/PRKCD/ACADM/NAPEPLD/ACADS/DECR1/MCEE/AIG1/PLA2G15/PLCG2/LDLR/ACOX1/ETFDH/ECI2/SLC27A2/HSD17B4/ACACB/LRP1/IDH1/ACOX2/ACBD5/GLA/FABP3/IRS2/BDH2/ABHD3/DECR2/MLYCD/APOA5/PNPLA8/ENPP7/SPHK1/DAGLB/PCCB/ECI1/CYP26B1/PRDX6/NUDT19/PNPLA5/ETFB/NAGA/PEX13/TYSND1/CPT1A/EHHADH/INPP5F/ACADVL/HADHA/AKR1B10/NUDT7/FABP5/PPARA/ACAA2/SRD5A3/ACER3/APOA1/ACOX3/NEU1/BCO2/SMPD1/PIK3CG/CYP26A1/CROT/MTOR/CYP4F3/ABCD1/ABHD16A/SMPD2/HACL1/SESN2/PNPLA4/HAO1/ACOT8	108
BP	GO:0032729	positive regulation of interferon-gamma production	39/7096	65/18670	0.0002614	0.004229	0.003153	CCR2/IL27RA/CLEC7A/SLC11A1/WNT5A/CEBPG/CD2/TNF/CD226/IL18R1/FAM49B/TLR4/PTPN22/HLA-DPB1/HLA-DPA1/PDE4B/HRAS/ABL1/IL1B/RASGRP1/IL1R1/IL12RB1/LGALS9/EBI3/FZD5/IRF8/IL18/FADD/CD276/TNFSF4/TLR8/HAVCR2/TXK/TLR3/TNFRSF13C/IL12B/CD244/CD3E/IL23A	39
BP	GO:0010212	response to ionizing radiation	77/7096	147/18670	0.0002632	0.004246	0.003165	NAMPT/ANXA1/CDKN1A/RAD51AP1/EYA3/MYC/NABP1/PTPRC/EGR1/CXCL10/ERCC6/TRIM13/RAD1/TGFB1/ALAD/USP28/UIMC1/INTS7/TMEM109/NET1/HSPA5/CASP3/HRAS/XRCC5/IKBIP/PML/THBD/CCL7/SIRT1/CCND1/RHNO1/ATM/TNKS1BP1/XRCC4/AEN/KAT5/POLG/BCL2/DNM2/BAX/ERCC1/RFWD3/SWI5/TSPYL5/GRB2/CYBA/INTS3/LIG4/TICRR/ZMPSTE24/KDM4D/FBXO4/BRCA1/ATR/DNMT3A/CLOCK/PRKAA1/HAMP/MDM2/XRCC6/DCLRE1C/DCUN1D3/RAD9A/TOPBP1/FANCD2/MEN1/POLB/GPX1/KRT14/BRCC3/BAK1/MGMT/PAXIP1/NUCKS1/SPIDR/FIGNL1/ERCC8	77
BP	GO:0061136	regulation of proteasomal protein catabolic process	93/7096	183/18670	0.0002668	0.004295	0.003202	CBFA2T3/TMTC3/PINK1/SMAD7/KEAP1/DDRGK1/FBXW7/LAMP3/BCAP31/HFE/RAD23B/FHIT/NUPR1/RYBP/APOE/GSK3B/PSME1/RNF19B/EDEM1/UBE2K/ALAD/SGTA/ZFAND2A/SOCS5/CSNK1D/RNF217/CEBPA/PLK2/ANKIB1/GCLC/OPHN1/PSMC4/SDCBP/UBE2J1/ARAF/CLU/UCHL5/UBE2G2/EDEM2/LRRK2/SUMO1/GLMN/HSPBP1/CSNK1A1/CSNK1E/RNFT1/ARIH2/PLK3/PSME3/UBQLN2/TRIB2/PRKACA/BBS7/DET1/NKD2/KLHL40/DERL2/STUB1/NFE2L2/ATXN3/COMMD1/NFE2L1/YOD1/BAG2/USP7/DVL1/MAP1A/PSEN1/FMR1/MDM2/PSMC1/TREM2/UBXN1/OGT/RNF185/HSP90AB1/CLEC16A/FOXF2/PSMC2/GPX1/VCP/AURKA/RBX1/BAG5/USP19/SMARCC1/KCNE2/CHFR/WNT10B/ERLEC1/OS9/MAPK9/RHBDF1	93
BP	GO:0042035	regulation of cytokine biosynthetic process	62/7096	114/18670	0.000269	0.004318	0.00322	KLF4/CCR2/TLR1/CX3CR1/CLEC7A/BCL10/ZFP36/IRF1/WNT5A/AZU1/STAT3/CEBPG/NLRP12/CEBPB/JAK2/PTPRC/EGR1/TNF/CD74/HMOX1/NFKB1/LILRB1/TICAM1/RELA/NMI/PTAFR/HSPB1/TRAF6/TLR4/IL1B/AGER/UBE2J1/TYROBP/IL6/GLMN/MAPKAPK2/TRIB2/IL1A/LAG3/INHBA/EBI3/CYBB/CD276/PSEN1/TLR8/SIGIRR/IFNG/CD4/TLR3/INHA/MAP2K5/LBP/TNFRSF13C/IL12B/ASB1/CD80/PRKCQ/APP/TIRAP/CD3E/TLR6/GHRL	62
BP	GO:0061013	regulation of mRNA catabolic process	100/7096	199/18670	0.0002731	0.004374	0.003261	MYD88/ZFP36/SLC11A1/VIM/PSMB9/TOB1/PSMB8/ZC3H14/NUP214/AGO2/PSMA5/PSMD11/YTHDF3/MOV10/TNPO1/HNRNPR/METTL14/GIGYF2/SECISBP2/PSME1/BTG2/THRAP3/PAIP1/FASTKD1/PSMB10/HSPB1/PSMA1/PSMA4/PRKCD/METTL3/SAMD4B/NPM1/PSMB1/PSMC4/DHX9/DCP2/PSMD13/ZC3H12D/PSMB3/PUM2/PSMB5/PSMD6/ZC3HAV1/PSMC3/SCGB1A1/FTO/HNRNPC/PSME3/GTPBP1/XRN1/MAPKAPK2/EXOSC2/PSMC6/HNRNPA0/RNASEL/CSDC2/UBC/TNRC6B/EXOSC7/TNRC6A/HNRNPD/CPEB3/YBX3/HNRNPM/TBRG4/CNOT7/FMR1/PSMC1/ZFP36L2/EIF4G1/PSMD8/PSMA2/EXOSC9/VIP/EXOSC3/PCID2/SET/PSMC5/PSMC2/PSMB2/PSMD4/MTOR/SAMD4A/EXOSC6/PNPT1/TIRAP/EXOSC8/PSMD1/ROCK2/PSMB4/NBAS/SYNCRIP/BOLL/TARDBP/PRKCA/PSMD9/PSMD3/EXOSC5/PLEKHN1/UPF1	100
BP	GO:0002287	alpha-beta T cell activation involved in immune response	37/7096	61/18670	0.0002746	0.004377	0.003263	PTGER4/NFKBIZ/ANXA1/STAT6/STAT3/BCL6/NLRP3/SMAD7/LY9/IL4R/BATF/IL18R1/SOCS5/SEMA4A/ZBTB7B/RELB/NFKBID/HMGB1/IL6/IL12RB1/LGALS9/HLX/IL18/TNFSF4/RORA/IFNG/ATP7A/IL12B/PRKCZ/CD80/TBX21/MTOR/FOXP1/GPR183/CCL19/MALT1/IL23A	37
BP	GO:0002293	alpha-beta T cell differentiation involved in immune response	37/7096	61/18670	0.0002746	0.004377	0.003263	PTGER4/NFKBIZ/ANXA1/STAT6/STAT3/BCL6/NLRP3/SMAD7/LY9/IL4R/BATF/IL18R1/SOCS5/SEMA4A/ZBTB7B/RELB/NFKBID/HMGB1/IL6/IL12RB1/LGALS9/HLX/IL18/TNFSF4/RORA/IFNG/ATP7A/IL12B/PRKCZ/CD80/TBX21/MTOR/FOXP1/GPR183/CCL19/MALT1/IL23A	37
BP	GO:0016569	covalent chromatin modification	217/7096	474/18670	0.0002798	0.004448	0.003316	USP51/USP3/SPI1/PINK1/SKI/BAZ1A/LMNA/JMJD6/DR1/BCL6/PHF19/EYA3/CHTOP/ENY2/KDM1B/PER2/DPY30/JAK2/SETDB2/LDB1/MORF4L2/UBE2N/ZNF304/EZH2/HAT1/PAF1/WDR5B/UHRF1/CHD1/RYBP/DOT1L/SUPT7L/KAT2B/MRGBP/SUV39H2/TET2/TRIM16/TRIM37/TGFB1/KDM7A/SIN3A/ZNF451/JADE3/ARRB1/MORC2/NCOA3/PRMT9/MTA3/PCGF2/PRKCD/MBD1/RUVBL2/ATXN7L3/RUVBL1/UIMC1/EPC2/MBIP/NSD1/DDB1/PCGF1/MSL3/ZBTB7B/MBD3/PCGF3/HSF4/KAT7/SETMAR/VEGFA/CDK5/YEATS4/SETD5/TAF5L/KDM2A/SIRT7/IL1B/PRDM4/HDAC11/MAP3K12/UBR5/KAT8/MIER1/TAF12/UBE2E1/UBE2A/CRTC2/SMARCAD1/PPM1F/SIRT1/SFPQ/ATXN7/NAA40/SIN3B/SETD7/BRD8/PAXBP1/SUDS3/CDK9/LRRK2/TAF5/SMYD3/PPARGC1A/FLCN/BCOR/MCRS1/BRMS1L/KDM4B/ATM/DTX3L/MUC1/HDAC10/FBL/KMT2E/HDAC2/NTMT1/AKAP8/KAT5/HDAC7/SUV39H1/MAPK8/NACC2/ASH1L/USP16/PRKD2/ELP3/KDM2B/SETD6/KDM8/BRPF1/NOC2L/HDAC4/DPF2/CTCF/SETDB1/RSF1/PADI1/PHF20/KDM5B/PRMT5/KDM6B/COPRS/ZMPSTE24/RING1/KDM4D/LEO1/RNF20/TAF6L/PWP1/CAMK2D/BRCA1/ING3/KANSL1L/DNMT3A/CLOCK/USP7/ELK4/EPC1/KAT2A/PRKAA1/FMR1/PHF10/PADI3/PHC1/VRK1/DDB2/EYA4/CPA4/TAF9B/USP49/PRDM2/EID1/PRDM6/OGT/BAP1/KDM5C/MCM3AP/CUL4B/RLF/CCNA2/FBLL1/JDP2/ING4/SET/MEN1/CARM1/JADE1/TBL1X/KMT2B/HDAC5/AURKA/USP22/CDC73/SNCA/MSL1/PAX7/BRCC3/PAX5/POLE4/GCG/EZH1/TADA3/MTA2/PAXIP1/PRMT1/ACTL6A/ATXN3L/UBE2B/WDR82/NR1H4/KAT6B/PRKCA/WDR5/TET1/TAF7/KDM4A/BRMS1/ZNF335/NAA60	217
BP	GO:0021795	cerebral cortex cell migration	28/7096	43/18670	0.0002838	0.00449	0.003347	SUN2/MBOAT7/FBXO45/CDK5/PAFAH1B1/SRGAP2C/P2RY12/ARX/DIXDC1/SYNE2/SRGAP2/NRP1/DISC1/NRP2/PEX13/NDEL1/DAB1/CDK5R2/EGFR/SLIT2/PSEN1/NR2E1/RELN/RHOA/RTN4/EFHC1/FGF13/LHX6	28
BP	GO:0033173	calcineurin-NFAT signaling cascade	28/7096	43/18670	0.0002838	0.00449	0.003347	IGF1/ATP2B4/CAMTA1/CHP1/CIB1/TNF/SLC9A1/GSK3B/DYRK2/PPP3CB/NFATC3/MAPK7/NRG1/RCAN3/HOMER3/LMCD1/NFATC1/NFATC2/RCAN1/NFAT5/MYOZ1/FHL2/EFHB/CHP2/LACRT/MTOR/CHERP/ERBB3	28
BP	GO:0060760	positive regulation of response to cytokine stimulus	35/7096	57/18670	0.0002852	0.004501	0.003356	TRIM32/TLR2/IRF7/PARP9/WNT5A/NLRC5/CREBRF/CD74/AXL/UBE2K/HIF1A/TLR4/DDX58/PAFAH1B1/DHX9/MMP12/CD300LF/IL7/IL1R1/MAVS/LSM14A/IFIH1/CASP1/ZBP1/FADD/ADAM17/TRAF2/CASP4/CPNE1/TREM2/TSLP/TXK/TRIM6/AGPAT1/AGPAT2	35
BP	GO:1902749	regulation of cell cycle G2/M phase transition	106/7096	213/18670	0.0002918	0.004593	0.003424	PRKAR2B/TUBA1A/NINL/PSMB9/CUL1/RAB11A/PSMB8/RNASEH2B/HUS1B/ATF5/ODF2/PSMA5/PSMD11/HAUS8/PSME1/GPR132/CNTRL/CDK4/TAOK3/SIN3A/CEP164/ZNF830/PSMB10/PCM1/MTA3/PSMA1/PSMA4/CSNK1D/CEP131/UIMC1/DBF4B/SYF2/NPM1/SFI1/PAFAH1B1/RAD51B/CDK5RAP2/PSMB1/PSMC4/DONSON/CEP76/PSMD13/MAPRE1/PSMB3/CCND1/PSMB5/PSMD6/ATM/CSNK1E/HAUS2/PSMC3/PSME3/RAD17/PSMC6/PRKACA/CKAP5/DCTN2/FHL1/CDC25A/CEP152/TUBA4A/VPS4B/FOXO4/TICRR/MIIP/DTL/CEP63/DYRK3/BRCA1/CEP57/RCC2/CETN2/HAUS5/TUBB4A/HAUS1/YWHAE/PSMC1/CLSPN/PSMD8/PSMA2/FBXL7/TOPBP1/FGFR1OP/YWHAG/PSMC5/PKIA/PSMC2/PSMB2/PSMD4/AURKA/BRSK1/APP/RBX1/BRCC3/CEP78/CCNB3/PSMD1/PAXIP1/ATAD5/WNT10B/PSMB4/ZFYVE19/PSMD9/KIF14/PSMD3/ALMS1	106
BP	GO:0051251	positive regulation of lymphocyte activation	158/7096	334/18670	0.0002937	0.004604	0.003433	IGF1/NOD2/PNP/CCR2/FYN/NFKBIZ/PTPN6/LILRB2/ANXA1/CDKN1A/BST1/CLEC7A/BCL10/LYN/MAD2L2/CD55/TNIP2/CSK/EGR3/STAT6/TNFRSF14/BCL6/NLRP3/DUSP10/CD40/MIF/IL4R/CBFB/MAP3K8/PTPRC/IL15/ADAM8/LAMP1/CD74/CD320/LILRB1/TICAM1/DPP4/IL7R/AXL/DOCK8/TGFB1/CCDC88B/PAK1/SOCS5/LEP/TNFSF13B/FAM49B/HLA-F/CORO1A/LILRB4/TRAF6/ZBTB1/FLT3LG/TLR4/ZBTB7B/HLA-DPB1/HLA-DPA1/HLA-E/NCK1/CD209/SLC39A10/NFKBID/PAK2/IL1B/AIF1/SIRPB1/AGER/CCL5/RASGRP1/RASAL3/PIK3R6/HLA-DMB/ICOSLG/HMGB1/EFNB1/IGFBP2/IL7/TYROBP/IL6ST/TESPA1/HLA-G/RAC1/TOX/TRBC1/IL6/IRS2/LCK/CYLD/FLOT2/CTLA4/VNN1/PDCD1LG2/MLH1/BCL2/BLOC1S3/NFATC2/CD47/CLCF1/LGALS1/PPP2R3C/CD1D/IL12RB1/GRB2/CD274/LGALS9/EBI3/ICOS/BTN2A2/MMP14/HES1/ADA/HLX/VAV1/IL18/FADD/AP3B1/CD276/TFRC/TNFSF4/SART1/AP1G1/CHRNB2/SOCS1/SIRPG/BAD/TNFRSF4/HAVCR2/IFNG/SPTA1/CD5/EXOSC3/PCID2/CD4/TNFRSF13C/IL12B/PRKCZ/CD80/TBX21/PRKCQ/RHOA/GPR183/CD83/EXOSC6/CCL19/MALT1/TIRAP/ZBTB16/CCR7/PAXIP1/CD3E/ATAD5/PDCD1/CD24/IL23A/IGHD/MEF2C/ZNF335	158
BP	GO:0001913	T cell mediated cytotoxicity	31/7096	49/18670	0.0002939	0.004604	0.003433	STX7/CD1C/CTSC/PTPRC/P2RX7/CD1E/LILRB1/IL7R/PPP3CB/FAM49B/HLA-F/HLA-E/HLA-B/AGER/CD1B/HLA-G/HLA-C/EMP2/PVR/CD1D/IL12RB1/CD1A/GZMM/ULBP2/FADD/PRF1/HLA-A/IL12B/MICA/RAB27A/IL23A	31
BP	GO:0048753	pigment granule organization	19/7096	26/18670	0.0003004	0.004695	0.0035	BLOC1S2/HPS4/ZEB2/TRAPPC6A/HPS1/ASIP/DTNBP1/BLOC1S6/RAB32/RAB38/BCL2/BLOC1S3/GPR143/KIF13A/BLOC1S1/BLOC1S4/AP3B1/AP1G1/AP1M1	19
BP	GO:0006790	sulfur compound metabolic process	174/7096	372/18670	0.0003036	0.004724	0.003522	ACOT13/SMS/HEXB/PDK4/SLC19A2/VCAN/GCLM/CHSY1/SOD1/CBR4/NDST2/SLC25A19/FAR2/PCYOX1/HMGCL/ADI1/ACPP/AHCY/MTR/IDS/NFU1/ACOT7/PAPSS1/ACSL5/MGST2/GSTP1/ACSM5/SLC7A11/IMPAD1/ELOVL5/GSR/HEXA/CHST13/MICAL1/PDK2/NFS1/GGCT/B3GNT2/ARSB/HMGCS1/ACOT9/ESD/SULT1C2/APIP/SCD/ISCU/OXSM/BTD/AKR1A1/CHST2/B4GALT6/CSGALNACT1/MICAL2/GNS/ACSL4/ACLY/ETHE1/TPST2/PAX8/MTRR/GCLC/STAT5A/ENOPH1/GSTO1/GSTZ1/MCEE/CSPG4/TECR/ST3GAL2/SLC25A10/XYLT1/CHST11/HSD17B4/MPC2/ACACB/OGDH/TPK1/SLC35D1/GSTA1/HAGH/IDH1/B3GALT6/ELOVL7/GLCE/GPX4/DGAT2/CHST5/IDUA/PCYOX1L/GSTM3/G6PD/TSTD1/CHST14/ALDH5A1/MLYCD/MCCC1/NUBPL/KYNU/XYLT2/MTAP/ACSL6/PDZD11/GLRX3/TST/PCCB/MGST1/MMACHC/MPST/SUOX/GSTM5/PAPSS2/CTH/THEM4/BHMT/GAL3ST4/NDST1/GSS/PDK1/CSGALNACT2/CNDP2/GAMT/SPOCK2/SLC5A6/HPGDS/ABHD14B/PDHB/B4GALT5/FAR1/BCAN/GSTM4/SUCLG2/AHCYL2/DLAT/NFE2L2/NFE2L1/HS3ST3B1/AHCYL1/PDP2/NUDT7/DBI/GGT7/PDHA2/MGST3/B3GNT4/GGTA1P/GGT5/ST3GAL1/THTPA/ISCA1/HSCB/PDP1/CHST12/ISCA2/SULT1B1/CHAC2/GPX1/PC/SNCA/B4GALT1/ELOVL6/ABCD1/GGTLC1/PDPR/GHR/CTNS/PHGDH/SLC35D2/TDO2/MAT1A/HSD17B12/CIAPIN1/CHST7/ACOT8/PIPOX	174
BP	GO:0030177	positive regulation of Wnt signaling pathway	91/7096	179/18670	0.0003038	0.004724	0.003522	TLR2/SKI/RBPJ/WNT5A/PSMB9/JRK/ZBED3/TNFAIP3/PSMB8/WLS/CSNK1G2/LGR4/PSMA5/PSMD11/ATP6V0C/GPRC5B/NFKB1/ZEB2/PSME1/PSMB10/PSMA1/PSMA4/CSNK1D/ROR2/RUVBL1/FZD9/ZRANB1/BMP2/ABL1/PSMB1/GID8/PSMC4/UBR5/FRAT1/RNF146/SFRP4/PSMD13/ATP6AP2/PSMB3/TRPM4/LRRK2/ASPM/SULF2/DDX3X/PSMB5/PSMD6/EDA/CSNK1E/DIXDC1/PSMC3/NRARP/PSME3/DISC1/PSMC6/KANK1/CSNK1G3/ZBED2/GSKIP/SEMA5A/DKK2/EGFR/LGR5/PSMC1/PSMD8/PSMA2/ARNTL/PIN1/ANKRD6/TBL1X/PSMC5/LGR6/TERT/PSMC2/PSMB2/PSMD4/VCP/PRDM15/CDH3/CDC73/SOX4/XIAP/PSMD1/UBE2B/WNT10B/PSMB4/CSNK1G1/DAAM2/PSMD9/PSMD3/MACF1/WNK2	91
BP	GO:0015980	energy derivation by oxidation of organic compounds	137/7096	285/18670	0.0003076	0.004771	0.003557	IGF1/CBFA2T3/PINK1/MDH1/UQCRC2/SLC25A25/PANK2/MYC/PER2/UQCR11/NDUFA8/AIFM2/GSK3B/AGL/PRELID1/DYRK2/ETFA/NDUFC1/FASTKD1/HIF1A/ISCU/NDUFB11/LEP/PPP1R3E/INSR/GYS1/PPP1R3D/GYG2/NDUFS3/NDUFA3/PPP1R2/CAT/ME3/NDUFA11/ETFDH/OGDH/IDH1/PHKB/UQCR10/ACO1/IL6ST/COX7C/IRS2/PPARGC1A/PCDH12/FLCN/PHKG1/ALDH5A1/IDH2/COX7A2L/DHTKD1/NDUFA4/MTFR1L/IMMP2L/SLC25A12/PGM2/SHMT2/PRKAG2/COX4I2/NDUFA1/MYBBP1A/CYP1A2/KHK/FH/INPP5K/PPP1R3B/MDH1B/COQ10B/OXA1L/ETFB/LYRM7/COQ9/PPP1R3F/COA6/COX15/NDUFA10/PDHB/CISD1/NDUFB1/NOA1/ACADVL/NDUFB5/IREB2/UQCRQ/SUCLG2/BLOC1S1/DLAT/TBRG4/NDUFS1/PPP1CC/PPP1CA/SLC25A13/IDH3A/NDUFB8/GFPT1/KL/PDHA2/DNAJC15/PID1/SURF1/NDUFB6/GAA/IFNG/FAHD1/PYGM/NR4A3/PPP1CB/NDUFB3/SDHA/PYGL/ESRRB/VCP/NDUFS7/NDUFAF2/NDUFV2/ND4/SDHD/MTOR/ME2/TAZ/IDH3G/GFPT2/SNCA/COQ10A/UQCRB/SLC25A22/PNPT1/NDUFB2/SDHAF2/COX6C/MTFR2/NNT/NDUFS2/G6PC/NDUFA7/FASTKD5/COX7B	137
BP	GO:0043618	regulation of transcription from RNA polymerase II promoter in response to stress	65/7096	121/18670	0.0003083	0.004772	0.003558	EPAS1/KLF2/RBPJ/TMBIM6/PSMB9/PSMB8/CEBPB/EGR1/PSMA5/PSMD11/HMOX1/PSME1/ATF4/HIGD1A/SIN3A/DNAJB1/HIF1A/HSF2/PSMB10/MAPK7/PSMA1/PSMA4/HSF4/HSPA5/NCK1/VEGFA/EGLN1/PSMB1/PSMC4/PSMD13/PSMB3/HIF1AN/EGLN3/CITED2/PSMB5/PSMD6/MUC1/PSMC3/PSME3/CHD6/NEDD4/PSMC6/UBC/ARNT/NFE2L2/IMPACT/E2F4/PSMC1/CUL2/RBL2/PSMD8/PSMA2/BACH1/PSMC5/PSMC2/PSMB2/PSMD4/MBTPS2/RBX1/PSMD1/PSMB4/SESN2/PSMD9/PSMD3/ATF6B	65
BP	GO:0042102	positive regulation of T cell proliferation	53/7096	95/18670	0.000317	0.004895	0.003649	IGF1/PNP/CCR2/LILRB2/ANXA1/CD55/PTPRC/IL15/CCDC88B/LEP/TNFSF13B/CORO1A/TRAF6/HLA-DPB1/HLA-DPA1/HLA-E/NCK1/CD209/IL1B/AIF1/AGER/CCL5/RASAL3/HLA-DMB/ICOSLG/HMGB1/EFNB1/IGFBP2/IL6ST/IL6/PDCD1LG2/CD1D/IL12RB1/CD274/LGALS9/EBI3/HES1/IL18/FADD/CD276/TFRC/TNFSF4/HAVCR2/SPTA1/CD4/TNFRSF13C/IL12B/CD80/PRKCQ/CCL19/CD3E/CD24/IL23A	53
BP	GO:0009411	response to UV	74/7096	141/18670	0.0003178	0.004896	0.00365	CRIP1/BMF/TRIM32/CDKN2D/CDKN1A/PTGS2/MYC/ERCC6/ERCC4/MAP3K4/ATF4/RELA/UBE4B/MAPK13/METTL3/USP28/RUVBL2/ZBTB1/HYAL2/TMEM161A/DDB1/CAT/CASP3/NPM1/PML/UBE2A/SIRT1/TIPIN/CCND1/EIF2S1/MAP4K3/RHNO1/POLH/ACTR5/TP53I13/MAPK8/BCL2/PCNA/NEDD4/BAX/NOC2L/ERCC1/YY1/USP1/CDC25A/ST20/HYAL3/DTL/SDE2/IMPACT/C9orf116/E2F4/EGFR/ATR/PRKAA1/FMR1/MDM2/DDB2/ERCC2/POLD1/RBL2/DCUN1D3/CUL4B/MEN1/IL12B/EIF2AK4/GPX1/TRIAP1/BRSK1/BAK1/UBE2B/FEN1/ZRANB3/ERCC8	74
BP	GO:0019722	calcium-mediated signaling	108/7096	218/18670	0.0003196	0.004901	0.003654	IGF1/SLC8A1/FPR2/HTR2B/CCR2/CX3CR1/ATP2B4/BST1/AZU1/GBP1/CAMTA1/MCOLN1/CHP1/CIB1/ACKR3/PTPRC/DEFB1/P2RX7/BCAP31/TNF/SLC9A1/PKD2/GSK3B/CD22/PDK2/DYRK2/PPP3CB/NFATC3/LAT2/ITPR1/FIS1/PTK2B/MYO5A/MAPK7/P2RY6/NRG1/MCU/RCAN3/CMKLR1/GSTO1/HINT1/HOMER3/PLCG2/P2RY12/DMD/TRPM4/TRPM2/CXCR1/LRRK2/CCR5/TMBIM4/SRI/SPHK1/NMUR2/TRAT1/LMCD1/NFATC1/NFATC2/HDAC4/ATP1B1/CCR6/PRKACA/RCAN1/GPR143/CXCR6/CCR4/PLEK/NFAT5/KSR2/DMTN/ZMPSTE24/ADA/GRIN2C/MYOZ1/CAMK2D/CCR3/EGFR/CXCR2/CCL20/ATP2A2/FHL2/CALML3/PRKAA1/CASQ1/TREM2/CASQ2/HRC/EFHB/CHP2/GPRC6A/CD4/TMEM38B/LACRT/SLA2/MTOR/CXCR3/P2RX2/CHERP/CCL4/ATP1A2/CCR7/CD3E/ACKR2/CCRL2/ERBB3/LAT/PTPRJ/P2RX5	108
BP	GO:0071156	regulation of cell cycle arrest	59/7096	108/18670	0.0003197	0.004901	0.003654	CDKN1A/MIF/RGCC/PKD2/BTG2/ZNF268/CDK4/TGFB1/TFAP4/FZD9/SETMAR/CDK5/PLK2/SFN/PML/HMGN5/CCND1/CDK9/UHRF2/ATM/TNKS1BP1/MIR34A/MUC1/MYOG/PLK3/MYBBP1A/PCNA/BAX/CRADD/ID2/CASP2/CDKN1B/CCNK/PRKACA/CNOT4/PLAGL1/ARID3A/FOXO4/EVI2B/CALR/SDE2/MED25/E2F4/BRCA1/CNOT7/GML/SLC25A33/MDM2/RBL2/HSP90AB1/PPP2R5B/CNOT10/CARM1/TRIAP1/AURKA/SOX4/PRMT1/BIN1/E2F8	59
BP	GO:0043407	negative regulation of MAP kinase activity	45/7096	78/18670	0.0003214	0.004916	0.003665	PTPN6/DUSP1/DUSP6/LYN/PPP2CA/DUSP5/NUP62/DUSP10/RGS2/UCHL1/DUSP7/GSTP1/IRAK3/APOE/HMGCR/DUSP3/DUSP18/PRKCD/HYAL2/MBIP/DUSP2/PTPN22/IL1B/PAQR3/BMP7/DUSP19/DUSP14/RGS3/DUSP4/BMP4/INPP5K/RGS14/CD300A/LAX1/SPRY1/SPRED1/CAV3/SPRY2/HIPK3/DNAJA1/SMPD1/GPS1/PDCD4/AIDA/PTPRJ	45
BP	GO:0035567	non-canonical Wnt signaling pathway	78/7096	150/18670	0.0003247	0.004955	0.003694	WNT5A/CELSR2/PSMB9/GNB1/PSMB8/AGO2/PSMA5/DVL2/PSMD11/MOV10/PSME1/PPP3CB/DAAM1/PFN1/PSMB10/PSMA1/PSMA4/CSNK1D/ROR2/IFT80/FZD9/ABL1/PSMB1/PSMC4/NLK/SFRP4/PSMD13/PDE6G/PSMB3/RAC1/GNG2/RNF213/PSMB5/PSMD6/CSNK1E/PSMC3/AP2A2/PSME3/NFATC1/PSMC6/ROR1/AGO1/AP2S1/TNRC6B/TNRC6A/MKS1/FZD5/CAMK2A/AP2A1/FZD1/PLCB1/FZD4/DVL1/WNT1/TCF7L2/CTHRC1/PSMC1/PSMD8/PSMA2/ANKRD6/FZD7/PSMC5/PSMC2/AP2M1/GPC4/PSMB2/PSMD4/RHOA/FZD2/GRHL3/PSMD1/WNT7A/SFRP5/PSMB4/DAAM2/PSMD9/PSMD3/FZD10	78
BP	GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response	15/7096	19/18670	0.0003323	0.005058	0.003771	BCL10/DDX21/WNT5A/MIF/CD74/GPRC5B/LILRB1/TICAM1/CD36/TLR4/DDX58/HLA-G/MAVS/DDX1/NR4A3	15
BP	GO:0002700	regulation of production of molecular mediator of immune response	73/7096	139/18670	0.0003385	0.00514	0.003832	NOD2/CCR2/IL27RA/BCL10/MAD2L2/DDX21/WNT5A/STAT6/TMBIM6/TNFRSF14/BCL6/NLRP3/SMAD7/CD40/MIF/IL4R/PTPRC/HFE/TNF/IRAK3/CD74/HMOX1/GPRC5B/LILRB1/TICAM1/CD22/CD226/TGFB1/IL18R1/FFAR2/CD36/HLA-F/TRAF6/CLC/TLR4/DDX58/HLA-E/RSAD2/IL1B/TRPM4/IL1R1/GPI/HLA-G/MAVS/IL6/CD96/MLH1/PARP3/CLCF1/DDX1/FZD5/KIR2DL4/IL18/TRAF2/TFRC/TNFSF4/IL13RA2/APOA1/TNFRSF4/TGFB3/NR4A3/EXOSC3/TLR3/TRIM6/PRKCZ/TBX21/APLF/EXOSC6/MALT1/CD244/PAXIP1/ATAD5/RBP4	73
BP	GO:0048871	multicellular organismal homeostasis	221/7096	485/18670	0.0003419	0.005171	0.003855	EPAS1/SPATA7/SLC40A1/NOD2/SIGLEC15/CCR2/SLC27A1/PIP/TRIM32/ACOT13/RAC2/METRNL/PDK4/DLL1/ACP5/PRKAR2B/APPL2/STMN1/ACVR2B/RBPJ/FABP4/SLC11A1/CSK/SOD1/DRAM2/ATP6AP1/AKR1B1/TPP1/STAT6/STAT3/BARD1/THRA/PTGS2/SPP1/RAB11A/HADH/TNFAIP3/PLAC8/ADIPOR1/S1PR1/ALDH1A1/LIPA/ABHD6/SNX10/LGR4/SLC22A5/PER2/IL4R/CEBPB/JAK2/CTSK/LDB1/IL15/P2RX7/EGR1/HFE/ADAM8/TNF/PRKACB/ZNF516/ERCC6/GIGYF2/KRAS/BBS10/ATF4/PBLD/CHMP4B/ACTB/CPT2/ARRDC3/CLN8/IL18R1/IP6K1/ZNF830/WFS1/SCD/HSPB1/CD36/PTK2B/PRDX1/LEP/NR1H2/SRF/CORO1A/TRAF6/HYAL2/NAPEPLD/FLT3LG/TCIRG1/PIWIL4/IL20RB/TLR4/ZBTB7B/DECR1/PDGFC/TP53INP2/ADRB1/IGF1R/VEGFA/SFN/CMKLR1/OMA1/UCP2/IL1B/LTBP3/MEX3C/NR1D2/CYTL1/ACACB/GATM/TNFRSF11A/BBS2/MUC2/BBS12/IL7/MKKS/TRPM2/HOMER1/RAC1/PLEKHM1/TFE3/ADCY7/IL6/G0S2/RDH12/PPARGC1A/FLCN/CRTC1/ADCY1/BBS4/GRB10/CRTC3/TMEM64/NPHP4/MAK/FTO/STRAP/PLCL1/BCL2/ADCY3/FH/BAX/INPP5K/CYP26B1/NR1H3/PRKACA/IL1A/ADRB2/FFAR4/WDR36/UGCG/MKS1/KSR2/ACADVL/AMPD2/KDM6B/F2R/UCP1/LCA5/ANKRD11/FABP5/EGFR/IL18/ADAM17/COL2A1/AQP3/TFRC/ADIPOR2/PRKAA1/HAMP/DCSTAMP/MUC6/EIF4G1/PLCL2/TMEM79/ARNTL/NXNL1/OGT/NR4A3/CLDN18/GCNT2/CD34/RB1/LACRT/DBH/ESRRB/GPX1/CSF1R/TRPV4/CDH3/RAB3D/MFAP2/ELOVL6/IAPP/ATP6V1B1/AMPD3/GRHL3/CIB2/MET/LPCAT1/SLN/TULP1/DIO2/CCDC66/TMEM119/WNT10B/GJA1/SMO/PRKCA/RBP4/AVPR2/RP1/POC1B/ALMS1/TRPV2/GRHL1/NTSR1/GHRL/ALB/APLN/PRKAB1	221
BP	GO:2000108	positive regulation of leukocyte apoptotic process	20/7096	28/18670	0.0003421	0.005171	0.003855	ANXA1/LYN/WNT5A/P2RX7/ADAM8/PRELID1/RAPGEF2/IDO1/NFKBID/CCL5/SIRT1/FNIP1/BAX/PIK3CD/CD274/LGALS9/NR4A3/PDCD1/MEF2C/PIK3CB	20
BP	GO:0045953	negative regulation of natural killer cell mediated cytotoxicity	12/7096	14/18670	0.0003475	0.005227	0.003897	SERPINB9/LILRB1/HLA-F/HLA-E/CLEC12B/CRK/HLA-G/LGALS9/KIR2DL4/HAVCR2/SERPINB4/MICA	12
BP	GO:0070672	response to interleukin-15	12/7096	14/18670	0.0003475	0.005227	0.003897	IL2RG/STAT3/IL15/IL2RB/ACSL4/STAT5A/SHC1/IL15RA/GRB2/PLCB1/JAK1/CD4	12
BP	GO:0043367	CD4-positive, alpha-beta T cell differentiation	43/7096	74/18670	0.0003494	0.005245	0.00391	PTGER4/NFKBIZ/ANXA1/STAT6/STAT3/BCL6/NLRP3/SH3RF1/SMAD7/LY9/IL4R/CBFB/BATF/FUT7/IL18R1/SOCS5/SEMA4A/ZBTB7B/RELB/RSAD2/NFKBID/HMGB1/IL6/IL12RB1/LGALS9/HLX/IL18/TNFSF4/SOCS1/RORA/IFNG/ATP7A/IL12B/PRKCZ/CD80/TBX21/MTOR/FOXP1/GPR183/CD83/CCL19/MALT1/IL23A	43
BP	GO:0070555	response to interleukin-1	103/7096	207/18670	0.0003547	0.005311	0.003959	MYD88/NOD2/KLF2/GBP2/ANXA1/IL1R2/TNIP2/GBP1/PSMB9/CUL1/TFPI/PSMB8/SQSTM1/CEBPB/MAP3K8/EGR1/UBE2N/PSMA5/PSMD11/IRAK3/NFKBIA/VRK2/HNMT/NFKB1/IL1RAP/PSME1/MIR142/RELA/IRAK4/HIF1A/PSMB10/PSMA1/PSMA4/TAB3/MAPK13/TRAF6/HYAL2/IKBKG/CACTIN/GCLC/PSMB1/IL1B/PSMC4/CCL5/PSMD13/TNFRSF11A/PSMB3/CCL7/IL1RN/IL1R1/CHI3L1/IL6/ADAMTS12/PSMB5/PSMD6/ETS1/OTUD4/PSMC3/CCL13/TAB1/PSME3/CCL8/PSMC6/HDAC4/CD47/YY1/TOLLIP/IL1A/UBC/LGALS9/CYBA/HYAL3/PLCB1/USP10/CCL20/CCL26/PSMC1/PSMD8/RORA/IGBP1/PSMA2/ST18/MAPK11/PSMC5/PSMC2/PSMB2/PSMD4/APP/SNCA/CX3CL1/RBX1/CCL19/CHUK/CCL4/PSMD1/PSMB4/PELI2/CCL24/PRKCA/PSMD9/PSMD3/UPF1/MIR146A	103
BP	GO:0038034	signal transduction in absence of ligand	42/7096	72/18670	0.0003636	0.00542	0.004041	SRPX/FYN/STRADB/EYA3/BCL2A1/KITLG/TNF/GSK3B/CTNNA1/MAPK7/MCL1/HTRA2/CASP3/IL1B/IL7/DCC/WWOX/BCL2L11/BCL2/BAX/CASP2/IL1A/INHBA/UNC5B/PPP1CA/PPP2R1B/FADD/COL2A1/ZC3HC1/EYA4/BAD/MKNK2/MOAP1/RET/MAP2K5/TERT/CX3CL1/BAK1/BCL2L2/APPL1/ERBB3/FOXO3	42
BP	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand	42/7096	72/18670	0.0003636	0.00542	0.004041	SRPX/FYN/STRADB/EYA3/BCL2A1/KITLG/TNF/GSK3B/CTNNA1/MAPK7/MCL1/HTRA2/CASP3/IL1B/IL7/DCC/WWOX/BCL2L11/BCL2/BAX/CASP2/IL1A/INHBA/UNC5B/PPP1CA/PPP2R1B/FADD/COL2A1/ZC3HC1/EYA4/BAD/MKNK2/MOAP1/RET/MAP2K5/TERT/CX3CL1/BAK1/BCL2L2/APPL1/ERBB3/FOXO3	42
BP	GO:0009167	purine ribonucleoside monophosphate metabolic process	160/7096	340/18670	0.0003663	0.005447	0.004061	IGF1/CBFA2T3/HK3/LDHA/PINK1/FBP1/PGK1/VPS9D1/STAT3/PFKFB3/NUP62/NUP160/PFKM/UQCRC2/PFKP/GAPDH/SLC25A25/NUP214/SLC2A6/P2RX7/UQCR11/NDUFA8/NUPR1/AK3/PGAM1/AK2/PKM/GALK1/EIF6/TPI1/MPP1/ZBTB7A/NDUFC1/TGFB1/GMPS/NUP85/CLPX/HIF1A/ISCU/SEH1L/NDUFB11/ADK/INSR/ALDOC/NDUFS3/GUK1/PAICS/NUP43/IMPDH1/NDUFA3/NMNAT1/ATP6V1A/ENO1/DNAJC30/ALDOA/UQCC2/NDUFA11/PARG/POM121/OGDH/CHCHD10/UQCR10/NUDT9/COX7C/GPI/ATP6V1B2/PFKFB4/PPARGC1A/FLCN/COX7A2L/DHTKD1/NDUFA4/SLC25A12/SHMT2/LDHC/PRKAG2/MYOG/NCOR1/COX4I2/NDUFA1/NUDT3/PFKFB1/GMPR2/ATIC/NUP88/HDAC4/ATP1B1/NUDT5/TEFM/COQ9/NUP107/PPAT/COA6/COX15/NDUFA10/FOXK2/NDUFB1/DDIT4/NDUFB5/UQCRQ/AMPD2/PGK2/PFKFB2/ADA/ARNT/DNM1L/NDUFS1/SLC25A33/PPARA/NUP93/SLC25A13/NDUFB8/PRKAA1/PSEN1/DNAJC15/NUP205/ENO2/PID1/SURF1/NDUFB6/BAD/SLC4A1/TREM2/NUP50/IFNG/PRKAG1/OGT/ATP7A/NDUFB3/SDHA/ESRRB/ZBTB20/VCP/NDUFS7/ADPGK/NDUFV2/ND4/SDHD/RHOA/TAZ/APP/SNCA/UQCRB/ATP6V1B1/AMPD3/ABCD1/NDUFB2/SDHAF2/LHPP/MYH3/COX6C/ATP1A2/PFKL/CTNS/NDUFS2/POM121C/AAAS/FIGNL1/NDUFA7/COX7B	160
BP	GO:0046390	ribose phosphate biosynthetic process	143/7096	300/18670	0.0003674	0.005451	0.004064	IGF1/CBFA2T3/HK3/PDK4/UPP1/LDHA/PINK1/FBP1/PGK1/CBR4/VPS9D1/STAT3/PFKFB3/NUP62/NUP160/PFKM/PFKP/GAPDH/PANK2/NUP214/ACOT7/PAPSS1/ACSL5/SLC2A6/P2RX7/ELOVL5/NUPR1/AK3/PGAM1/AK2/PKM/PDK2/GALK1/EIF6/TPI1/ZBTB7A/TGFB1/GMPS/NUP85/HIF1A/SCD/SEH1L/PANK3/ADK/INSR/ALDOC/PRPSAP1/PANK1/GUK1/PAICS/NUP43/IMPDH1/ACSL4/CTPS2/ACLY/ENO1/DNAJC30/ALDOA/GSTZ1/CMPK1/TECR/POM121/MPC2/ACACB/RFK/OGDH/ELOVL7/GPI/ADCY7/G6PD/PFKFB4/PPARGC1A/FLCN/MLYCD/ADCY1/DHTKD1/NME3/ACSL6/SLC25A12/LDHC/NME4/PRKAG2/MYOG/NCOR1/PFKFB1/ATIC/ADCY3/NUP88/HDAC4/PAPSS2/NME1/NUP107/PDK1/PRPS1/PPAT/PDHB/FOXK2/DDIT4/AMPD2/PGK2/PFKFB2/ARNT/DLAT/PDP2/UCK1/PPARA/NUP93/SLC25A13/PRKAA1/PSEN1/PDHA2/NUP205/ENO2/PID1/GUCY2D/SLC4A1/PRPS1L1/TREM2/CTPS1/CAD/NUP50/IFNG/PRKAG1/OGT/PDP1/PRPS2/PYGL/ESRRB/ZBTB20/VCP/ADPGK/UCKL1/TAZ/APP/SNCA/ELOVL6/UPP2/AMPD3/PDPR/PFKL/POM121C/AAAS/HSD17B12	143
BP	GO:0001659	temperature homeostasis	88/7096	173/18670	0.0003691	0.005463	0.004073	EPAS1/CCR2/SLC27A1/ACOT13/APPL2/ACVR2B/RBPJ/FABP4/STAT6/STAT3/THRA/PTGS2/HADH/PLAC8/ADIPOR1/ALDH1A1/ABHD6/LGR4/PER2/IL4R/CEBPB/JAK2/IL15/EGR1/TNF/ZNF516/ATF4/CPT2/ARRDC3/IL18R1/IP6K1/SCD/CD36/LEP/NR1H2/NAPEPLD/TLR4/ZBTB7B/DECR1/PDGFC/ADRB1/IGF1R/VEGFA/CMKLR1/OMA1/UCP2/IL1B/GATM/TNFRSF11A/TRPM2/TFE3/G0S2/PPARGC1A/FLCN/GRB10/FTO/PLCL1/FH/NR1H3/IL1A/ADRB2/FFAR4/KSR2/ACADVL/KDM6B/UCP1/FABP5/IL18/ADAM17/ADIPOR2/PLCL2/ARNTL/OGT/RB1/DBH/GPX1/MFAP2/ELOVL6/SLN/DIO2/WNT10B/GJA1/ALMS1/TRPV2/NTSR1/GHRL/APLN/PRKAB1	88
BP	GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	21/7096	30/18670	0.0003789	0.005583	0.004163	NFKBIZ/ANXA1/NLRP3/IL4R/SOCS5/ZBTB7B/NFKBID/IL12RB1/LGALS9/HLX/IL18/TNFSF4/SOCS1/IFNG/IL12B/PRKCZ/CD80/CD83/CCL19/MALT1/IL23A	21
BP	GO:0061082	myeloid leukocyte cytokine production	21/7096	30/18670	0.0003789	0.005583	0.004163	BCL10/DDX21/WNT5A/BCL6/MIF/IRAK3/CD74/HMOX1/GPRC5B/LILRB1/TICAM1/TGFB1/CD36/TLR4/DDX58/SIRT1/HLA-G/MAVS/DDX1/TGFB3/NR4A3	21
BP	GO:0034612	response to tumor necrosis factor	148/7096	312/18670	0.0003847	0.005656	0.004217	CRHBP/ASAH1/KLF2/TRIM32/GBP2/GCH1/ZFP36/FABP4/GBP1/CD58/PTPN2/PTGS2/PSMB9/TNFRSF14/TNFAIP3/CD40/PSMB8/BIRC2/CIB1/ACTN4/STAT1/JAK2/GSTP1/PSMA5/TNF/PSMD11/NFKBIA/TNFRSF21/NFKB1/PSME1/AIM2/MIR142/RELA/PSMB10/PTK2B/TXNDC17/PSMA1/TNFSF13B/PSMA4/HYAL2/SPPL2A/IKBKG/TRAF3/CEBPA/CARD14/TNFRSF12A/CASP3/CACTIN/CASP8/PSMB1/PSMC4/CCL5/DHX9/ARHGEF2/PSMD13/SPATA2/TNFRSF11A/TRADD/PSMB3/CCL7/TNFRSF18/RBCK1/SIRT1/CHI3L1/MAP4K3/ADAMTS12/CYLD/PPARGC1A/PSMB5/PSMD6/EDA/MIR34A/PSMC3/SPHK1/CCL13/MYOG/PSME3/EDAR/CCL8/PSMC6/INPP5K/HDAC4/BIRC3/SGMS1/CASP1/GSS/PRPF8/RFFL/CYBA/HYAL3/YBX3/KRT8/HIPK1/MAP3K5/TRAF1/PIAS3/NFE2L2/BRCA1/ADAM17/TRAF2/CCL20/CASP4/TNFRSF13B/CCL26/ADAM9/TNFSF4/CPNE1/KAT2A/TAX1BP1/HAMP/DCSTAMP/MAPK1/PID1/APOA1/PSMC1/ZFP36L2/TNFRSF4/PSMD8/RORA/IGBP1/PSMA2/ST18/CLDN18/TNFSF18/TNFRSF25/TNFRSF13C/WDR35/PSMC5/PSMC2/PSMB2/PSMD4/LIMS1/CX3CL1/CLIP3/ZFAND6/CCL19/AFF3/CHUK/CCL4/PSMD1/TNFSF8/ENDOG/PSMB4/CCL24/NR1H4/PSMD9/PSMD3/FOXO3	148
BP	GO:0006625	protein targeting to peroxisome	40/7096	68/18670	0.000392	0.005725	0.004268	HMGCL/PEX12/ACAA1/PHYH/SCP2/MPV17/PEX16/ECH1/UBE2D3/UBE2D2/USP9X/CAT/AGPS/ACOX1/ECI2/SLC27A2/HSD17B4/IDH1/ACOX2/DAO/DECR2/MLYCD/NUDT19/PEX13/TYSND1/PEX3/UBC/PEX19/EHHADH/RAB8B/NUDT7/PEX14/ACOX3/GNPAT/CROT/ZFAND6/HACL1/HAO1/ACOT8/PIPOX	40
BP	GO:0072662	protein localization to peroxisome	40/7096	68/18670	0.000392	0.005725	0.004268	HMGCL/PEX12/ACAA1/PHYH/SCP2/MPV17/PEX16/ECH1/UBE2D3/UBE2D2/USP9X/CAT/AGPS/ACOX1/ECI2/SLC27A2/HSD17B4/IDH1/ACOX2/DAO/DECR2/MLYCD/NUDT19/PEX13/TYSND1/PEX3/UBC/PEX19/EHHADH/RAB8B/NUDT7/PEX14/ACOX3/GNPAT/CROT/ZFAND6/HACL1/HAO1/ACOT8/PIPOX	40
BP	GO:0072663	establishment of protein localization to peroxisome	40/7096	68/18670	0.000392	0.005725	0.004268	HMGCL/PEX12/ACAA1/PHYH/SCP2/MPV17/PEX16/ECH1/UBE2D3/UBE2D2/USP9X/CAT/AGPS/ACOX1/ECI2/SLC27A2/HSD17B4/IDH1/ACOX2/DAO/DECR2/MLYCD/NUDT19/PEX13/TYSND1/PEX3/UBC/PEX19/EHHADH/RAB8B/NUDT7/PEX14/ACOX3/GNPAT/CROT/ZFAND6/HACL1/HAO1/ACOT8/PIPOX	40
BP	GO:1903829	positive regulation of cellular protein localization	153/7096	324/18670	0.0004003	0.005833	0.004348	ITGAM/FYN/EZR/RAC2/PLS1/ARF6/PINK1/PARP9/SYT11/NUP62/LRIG2/OAZ2/PTGS2/RAB11A/CHP1/HPS4/FLNA/PMAIP1/DDRGK1/CIB1/FBXW7/YWHAH/SQSTM1/ABHD17C/BCAP31/TNF/C2CD5/EPHB2/RAN/GSK3B/EDEM1/HCLS1/CSNK2A2/TGFB1/RDX/MIEF1/FIS1/SAR1B/PAK1/PCM1/LEP/PRKCD/UBE2D3/CEP131/HYAL2/RHOG/HTRA2/KAT7/CDK5/SFN/HRAS/CASP8/EMD/ZPR1/IL1B/CNST/UBR5/ATG13/LRP1/TYROBP/NPTN/RAB29/SPTBN1/CCDC88A/MAVS/SNX33/EDEM2/CYLD/MYO1C/RHOU/PDCD5/MCRS1/BICD1/SAR1A/DTX3L/ARIH2/PLK3/MAPK8/ABLIM3/NDC80/BCL2/CD247/BCAS3/MICALL2/GZMB/TSG101/KIF20B/PRKACA/MGAT3/CNPY4/UBL4B/RANGRF/NKD2/YWHAQ/SREBF2/FZD5/CD2AP/ITGA3/CCT4/ABCA7/HSPA1L/CCT8/CEMIP/EGFR/GPSM2/RIOK2/MAP1A/STAC2/PRKAA1/PSEN1/MDM2/MAPK1/TCF7L2/SH3GLB1/YWHAE/EPB41/MSN/BAD/TREM2/UBL5/RUFY3/IFNG/PPP1R13B/BAP1/CHP2/GNL3L/KIF5B/B3GAT3/TMEM30A/HSP90AB1/CACNB3/YWHAG/CARD10/EPB41L2/TERT/RTN4/CLIP3/ITGB1BP1/PDCD10/SSH1/RER1/TM9SF4/LRP4/ICE1/ROCK2/XPO4/GNL3/SMO/TARDBP/SESN2/CTDSPL2/GAS8/SEC16B	153
BP	GO:0006513	protein monoubiquitination	39/7096	66/18670	0.0004061	0.005902	0.0044	CUL1/KLHL12/PEX12/BIRC2/PAF1/UHRF1/RYBP/UBE4B/TRIM37/PCGF2/UBE2D3/ATXN7L3/DDB1/PCGF1/PCGF3/KLHL22/UBE2W/UBE2E1/BCOR/DTX3L/KBTBD8/TRIM21/KDM2B/RNF126/TSG101/PEF1/RING1/LEO1/DTL/RNF20/FANCL/FANCM/DDB2/FBXL2/CUL4B/TOPORS/CDC73/RBX1/UBE2B	39
BP	GO:0032814	regulation of natural killer cell activation	22/7096	32/18670	0.0004105	0.005941	0.004429	IL15/LAMP1/TICAM1/AXL/LEP/HLA-F/ZBTB1/FLT3LG/PTPN22/HLA-E/RASGRP1/TYROBP/TOX/BLOC1S3/RHBDD3/PGLYRP4/IL18/AP1G1/HAVCR2/IL12B/MICA/IL23A	22
BP	GO:0045589	regulation of regulatory T cell differentiation	22/7096	32/18670	0.0004105	0.005941	0.004429	LILRB2/IRF1/BCL6/DUSP10/CBFB/TGFB1/LILRB4/TNFRSF18/HLA-G/CR1/CTLA4/NFATC2/LAG3/LGALS9/BTN2A2/TNFSF4/KAT2A/SOCS1/IFNG/FANCD2/DROSHA/FANCA	22
BP	GO:0019079	viral genome replication	65/7096	122/18670	0.000417	0.006022	0.004489	PLSCR1/OASL/IFITM2/CTBP2/TNF/IFITM1/UBP1/NFIA/IFITM3/PCBP1/MORC2/ISG20/STAU1/DDB1/DEK/ADARB1/OAS3/IFI27/CD209/RSAD2/CCL5/SRPK2/ISG15/VAPB/APOBEC3G/RAB29/MAVS/APOBEC3C/IFIT5/DDX3X/ILF3/BANF1/ZC3HAV1/TARBP2/BCL2/CCL8/TBC1D20/TNIP1/INPP5K/CCNK/MX1/RAB5A/TOP2B/SETDB1/RNASEL/PCBP2/CXCR6/IFIT1/SRPK1/LAMTOR5/EIF2AK2/CNOT7/PKN2/FMR1/FBXL2/ATG16L2/TRIM6/EIF2AK4/VCP/ADAR/PPIB/ROCK2/NUCKS1/TOP2A/BTBD17	65
BP	GO:0010675	regulation of cellular carbohydrate metabolic process	74/7096	142/18670	0.000419	0.006036	0.0045	IGF1/CBFA2T3/PDK4/FBP1/STAT3/PTPN2/PMAIP1/ADIPOR1/SIK1/SLC45A3/COX11/NUPR1/GSK3B/KAT2B/PGAM1/PDK2/DYRK2/PTAFR/IGFBP4/PTK2B/LEP/PPP1R3E/INSR/P2RY6/PPP1R3D/DDB1/SLC35B4/ACACB/SIRT1/DGAT2/IRS2/DUSP12/PPARGC1A/MLYCD/NLN/GNB3/LCMT1/SLC25A12/MYOG/KHK/PFKFB1/INPP5K/HDAC4/PPP1R3B/PDK1/PPP1R3F/PLEK/FOXK2/DDIT4/PFKFB2/ZMPSTE24/NFE2L1/SERPINA12/PPP1CA/MST1/PPARA/KAT2A/BAD/RORA/OGT/PPP1CB/ESRRB/MTOR/SNCA/CD244/GCG/ADCYAP1R1/SESN2/C1QTNF3/WDR5/P2RY1/FAM3A/NTSR1/NKX1-1	74
BP	GO:0110053	regulation of actin filament organization	126/7096	261/18670	0.0004223	0.006067	0.004523	MYADM/S100A10/CDC42EP4/VASP/PTGER4/ARF6/STMN1/FHOD1/TSC1/C9orf72/ARAP1/SORBS3/HCK/RHOBTB1/PLEKHG2/FLNA/RHOC/S1PR1/RGCC/TMSB10/SPIRE1/SLC9A1/IQGAP2/ARHGEF10L/ACTR2/CXCL12/TMOD3/LIMA1/HCLS1/EVL/TWF2/RDX/PFN1/CDC42EP2/PAK1/PTK2B/CFL2/CAPZA2/SWAP70/PRKCD/LATS1/GMFG/CORO1A/BAIAP2/ARFGEF1/CAPG/NCK1/ABL1/FCHSD1/ARPC1A/CAPZA1/PPM1F/MKKS/SH3BP1/RAC1/ARPIN/SPTBN1/ARPC1B/CDC42EP3/CYFIP1/MYO1C/CORO1B/ARHGAP6/BBS4/LIMCH1/ARF1/ARPC5L/NRP1/COTL1/TPM1/AVIL/INPP5K/CD47/CFL1/KANK1/TRIOBP/ARHGAP18/ADD3/GRB2/PLEK/JMY/ACTR3B/SHANK1/FER/SEMA5A/LPAR1/DMTN/ACTR3/PXN/CLASP2/LMOD3/SCIN/PREX1/SLIT2/CCL26/APOA1/ARPC4/TGFB3/SPTA1/SPTBN2/SYNPO2L/TACSTD2/TMEFF2/ARPC2/KANK3/MTOR/RHOA/PICK1/CX3CL1/ITGB1BP1/SNX9/MET/CCR7/WAS/ROCK2/RHOBTB2/CCL24/ASAP3/SHANK3/SERPINF2/BIN1/NCKAP1/FCHSD2/ALMS1/SYNPO/FMN1	126
BP	GO:0043473	pigmentation	54/7096	98/18670	0.000424	0.006067	0.004523	BLOC1S2/BBS5/RAB11A/HPS4/MLPH/KITLG/ZEB2/TRAPPC6A/MYO5A/CD63/HPS1/HPS3/FIG4/ASIP/DTNBP1/ATRN/VPS33A/MITF/BLOC1S6/ANKRD27/ATP6AP2/BBS2/MKKS/RAB32/RAB38/SPARC/BBS4/EDA/BCL2L11/EDAR/BCL2/BLOC1S3/BAX/DCTN2/BBS7/GPR143/KIF13A/BLOC1S1/BLOC1S4/ARCN1/DCT/AP3B1/KRT76/AP1G1/HPS6/ATP7A/AP1M1/MREG/CDH3/OCA2/RAB27A/GNA11/ADAMTS9/MEF2C	54
BP	GO:0046364	monosaccharide biosynthetic process	54/7096	98/18670	0.000424	0.006067	0.004523	TALDO1/FBP1/PGK1/MDH1/AKR1B1/PTPN2/GAPDH/SIK1/PER2/SLC37A4/KAT2B/PGAM1/ATF4/PDK2/TPI1/TKT/PCK2/LEP/AKR1A1/ALDOC/DDB1/ENO1/ALDOA/SLC25A10/SLC35B4/CRTC2/SIRT1/GPI/DGAT2/G6PD/PPARGC1A/NLN/SLC25A12/PFKFB1/FOXK2/SORD/GOT2/PGK2/SERPINA12/MST1/PPARA/SLC25A13/KAT2A/ENO2/OGT/PGD/PC/GCG/SESN2/RBP4/C1QTNF3/WDR5/G6PC/FAM3A	54
BP	GO:0031098	stress-activated protein kinase signaling cascade	149/7096	315/18670	0.0004311	0.006156	0.004589	NOD2/EZR/PTGER4/DUSP1/LYN/PINK1/ZFP36/OXSR1/TNIP2/WNT5A/SH2D3C/AKR1B1/ZNF622/CUL1/SH3RF1/STRADB/DUSP10/MAP2K1/MYC/GSTP1/MAP3K8/FAS/UBE2N/DVL2/TNF/ERCC6/NFKB1/ZEB2/MAP3K4/HMGCR/SLAMF1/DUSP3/IRAK4/TAOK3/GADD45B/HGF/PAK1/MAP4K5/PTK2B/PRDX1/LEP/ROR2/TAB3/MAPK13/TRAF6/IKBKG/NCF1/TLR4/PTPN22/TPD52L1/BMP2/KAT7/IGF1R/VEGFA/HRAS/ARHGEF6/PAFAH1B1/PAK2/IL1B/DTNBP1/SEMA4C/AGER/MAP3K12/RASGRP1/SDCBP/MDFIC/HMGB1/TNFRSF11A/IL1RN/SLK/MFHAS1/DUSP19/MAP4K2/MAP4K3/CYLD/RELL2/SPHK1/NCOR1/MAPK8/TAB1/ADORA2B/EDAR/MAPKAPK2/MAP3K6/MAP4K1/ZMYND11/MLKL/UBC/MAP2K2/MAP3K11/SH3RF3/LGALS9/FZD5/AMBP/BIRC7/MAP3K5/ZMPSTE24/PLCB1/EIF2AK2/EGFR/MUL1/CAV3/TRAF2/FZD4/MAPK1/MAP2K4/MAP3K13/PPEF2/IGBP1/EPHB1/MAPK11/HIPK3/DNAJA1/MAP3K1/ANKRD6/ULK4/TLR3/MAP2K5/FZD7/MEN1/MAP4K4/GPS1/RHOA/TRPV4/APP/ERN1/PDCD4/PDCD10/CCL19/TIRAP/NBR1/CHUK/NEK4/TRAF4/AIDA/STRADA/WNT7A/CCR7/PRMT1/IL26/DAXX/SERPINF2/TLR6/FZD10/NRK/MAPK9/SASH1/IL37/MAP3K9	149
BP	GO:0009126	purine nucleoside monophosphate metabolic process	160/7096	341/18670	0.0004336	0.006177	0.004605	IGF1/CBFA2T3/HK3/LDHA/PINK1/FBP1/PGK1/VPS9D1/STAT3/PFKFB3/NUP62/NUP160/PFKM/UQCRC2/PFKP/GAPDH/SLC25A25/NUP214/SLC2A6/P2RX7/UQCR11/NDUFA8/NUPR1/AK3/PGAM1/AK2/PKM/GALK1/EIF6/TPI1/MPP1/ZBTB7A/NDUFC1/TGFB1/GMPS/NUP85/CLPX/HIF1A/ISCU/SEH1L/NDUFB11/ADK/INSR/ALDOC/NDUFS3/GUK1/PAICS/NUP43/IMPDH1/NDUFA3/NMNAT1/ATP6V1A/ENO1/DNAJC30/ALDOA/UQCC2/NDUFA11/PARG/POM121/OGDH/CHCHD10/UQCR10/NUDT9/COX7C/GPI/ATP6V1B2/PFKFB4/PPARGC1A/FLCN/COX7A2L/DHTKD1/NDUFA4/SLC25A12/SHMT2/LDHC/PRKAG2/MYOG/NCOR1/COX4I2/NDUFA1/NUDT3/PFKFB1/GMPR2/ATIC/NUP88/HDAC4/ATP1B1/NUDT5/TEFM/COQ9/NUP107/PPAT/COA6/COX15/NDUFA10/FOXK2/NDUFB1/DDIT4/NDUFB5/UQCRQ/AMPD2/PGK2/PFKFB2/ADA/ARNT/DNM1L/NDUFS1/SLC25A33/PPARA/NUP93/SLC25A13/NDUFB8/PRKAA1/PSEN1/DNAJC15/NUP205/ENO2/PID1/SURF1/NDUFB6/BAD/SLC4A1/TREM2/NUP50/IFNG/PRKAG1/OGT/ATP7A/NDUFB3/SDHA/ESRRB/ZBTB20/VCP/NDUFS7/ADPGK/NDUFV2/ND4/SDHD/RHOA/TAZ/APP/SNCA/UQCRB/ATP6V1B1/AMPD3/ABCD1/NDUFB2/SDHAF2/LHPP/MYH3/COX6C/ATP1A2/PFKL/CTNS/NDUFS2/POM121C/AAAS/FIGNL1/NDUFA7/COX7B	160
BP	GO:0043094	cellular metabolic compound salvage	23/7096	34/18670	0.0004369	0.006197	0.00462	TYMP/PNP/UPP1/ADI1/DGUOK/APIP/ADK/ENOPH1/TK1/PRTFDC1/MTAP/GMPR2/BHMT/AMPD2/ADA/DCK/UCK1/TK2/CDA/UCKL1/UPP2/AMPD3/ADAL	23
BP	GO:0045066	regulatory T cell differentiation	23/7096	34/18670	0.0004369	0.006197	0.00462	LILRB2/IRF1/BCL6/DUSP10/CBFB/FUT7/TGFB1/LILRB4/TNFRSF18/HLA-G/CR1/CTLA4/NFATC2/LAG3/LGALS9/BTN2A2/TNFSF4/KAT2A/SOCS1/IFNG/FANCD2/DROSHA/FANCA	23
BP	GO:0042267	natural killer cell mediated cytotoxicity	36/7096	60/18670	0.0004458	0.00631	0.004704	PTPN6/SERPINB9/CEBPG/LAMP1/LILRB1/CD226/PRDX1/LEP/HLA-F/CORO1A/HLA-E/CLEC12B/RASGRP1/PIK3R6/CRK/HLA-G/GZMB/UNC13D/PVR/LAG3/LGALS9/ULBP2/CRTAM/VAV1/KIR2DL4/IL18/AP1G1/HAVCR2/NCR3/SERPINB4/IL12B/SH2D1A/MICA/NCR1/IL18RAP/RAB27A	36
BP	GO:0002887	negative regulation of myeloid leukocyte mediated immunity	10/7096	11/18670	0.0004513	0.006366	0.004746	CCR2/HMOX1/ABR/BCR/CD300A/LGALS9/RABGEF1/IL13RA2/CD84/FOXF1	10
BP	GO:0033238	regulation of cellular amine metabolic process	46/7096	81/18670	0.0004517	0.006366	0.004746	NQO1/ITGAM/ATP2B4/NR4A2/OAZ2/PSMB9/PSMB8/SIRT4/PSMA5/PSMD11/SLC7A11/PSME1/SLC7A7/PSMB10/PSMA1/PNKD/PSMA4/OAZ3/PSMB1/ODC1/PSMC4/PSMD13/PSMB3/PSMB5/PSMD6/PSMC3/PSME3/PSMC6/BHMT/AZIN1/MAOB/CHRNB2/PSMC1/PSMD8/PSMA2/PSMC5/PSMC2/PSMB2/PSMD4/SNCA/ATCAY/PSMD1/PSMB4/NR1H4/PSMD9/PSMD3	46
BP	GO:0042093	T-helper cell differentiation	35/7096	58/18670	0.0004578	0.006395	0.004767	PTGER4/NFKBIZ/ANXA1/STAT6/STAT3/BCL6/NLRP3/SMAD7/LY9/IL4R/BATF/IL18R1/SOCS5/SEMA4A/ZBTB7B/RELB/NFKBID/HMGB1/IL6/IL12RB1/HLX/IL18/TNFSF4/RORA/ATP7A/IL12B/PRKCZ/CD80/TBX21/MTOR/FOXP1/GPR183/CCL19/MALT1/IL23A	35
BP	GO:0002755	MyD88-dependent toll-like receptor signaling pathway	24/7096	36/18670	0.0004581	0.006395	0.004767	MYD88/TLR1/TLR2/IRF7/IRF1/LY96/IRAK3/IRAK4/CD36/TLR5/TAB3/TRAF6/TLR4/CD300LF/TAB1/TNIP1/TLR10/UBC/CD300A/TLR8/REG3G/MAP3K1/TIRAP/TLR6	24
BP	GO:1902622	regulation of neutrophil migration	24/7096	36/18670	0.0004581	0.006395	0.004767	RAC2/BST1/CAMK1D/ADAM8/CD74/MPP1/CD99/IL1R1/RAC1/C3AR1/MOSPD2/CD99L2/C1QBP/CXCR2/JAM3/SLIT2/LBP/C5AR2/DAPK2/CCL19/TIRAP/CCR7/SLAMF8/IL23A	24
BP	GO:2001171	positive regulation of ATP biosynthetic process	24/7096	36/18670	0.0004581	0.006395	0.004767	IGF1/PINK1/STAT3/PFKFB3/P2RX7/HIF1A/INSR/ENO1/PFKFB4/PPARGC1A/SLC25A12/PFKFB1/PFKFB2/ARNT/PRKAA1/PSEN1/PID1/TREM2/IFNG/ESRRB/ZBTB20/VCP/TAZ/APP	24
BP	GO:1901214	regulation of neuron death	148/7096	313/18670	0.0004588	0.006395	0.004767	NQO1/ITGAM/FOS/FYN/CX3CR1/GRN/ATG7/NR4A2/PINK1/GCLM/RILPL1/AIFM1/WNT5A/TSC1/SOD1/GPNMB/STAT3/CAPN2/CHP1/ALKBH1/FBXW7/LGMN/CEBPB/JAK2/EGR1/ADAM8/TNF/SLC7A11/HMOX1/NUPR1/KRAS/APOE/GSK3B/BTG2/REL/ATF4/AXL/CHMP4B/STXBP1/ZNF746/FIS1/ARRB1/HIF1A/WFS1/PTK2B/HLA-F/CORO1A/IKBKG/MCL1/HTRA2/TLR4/ITSN1/FZD9/PARP2/CDK5/CASP3/HRAS/NMNAT1/ABL1/GCLC/CTSZ/CASP8/ZPR1/NCOA7/CLN3/CCL5/MAP3K12/SRPK2/LRP1/CREB1/CLU/SIRT1/TYROBP/EIF2S1/RAB29/LRRK2/DCC/CD200R1/G6PD/EGLN3/PPARGC1A/ATM/SNX6/BCL2L11/NRP1/BCL2/AIMP2/KDM2B/BAX/HDAC4/CASP2/CLCF1/SYNGAP1/AKT1S1/MAP3K11/UNC5B/PITX3/LIG4/DDIT4/MAP3K5/BHLHB9/F2R/FZD1/NSMF/CNTF/PPARA/TRAF2/WNT1/PSEN1/UBE2M/CNTFR/STAMBP/PSMC1/MAP2K4/BAD/EIF4G1/TGFB3/EPHB1/IFNG/PPP1R13B/FAIM2/NR4A3/HYOU1/PIN1/CD34/HSP90AB1/LANCL1/SET/TERT/MTOR/RHOA/TYRO3/SNCA/CX3CL1/SIGMAR1/SSH1/PTPRZ1/SLC30A10/PICALM/DAXX/ERBB3/TLR6/KIF14/FOXO3/NTRK2/MEF2C/OXR1/GDF5	148
BP	GO:0048524	positive regulation of viral process	58/7096	107/18670	0.0004676	0.006478	0.004829	CD74/CHD1/VPS37B/APOE/CHMP4B/STAU1/DDB1/TFAP4/ADARB1/IGF2R/TAF11/CCL5/DHX9/GTF2F2/SRPK2/MDFIC/POLR2L/VAPB/TRIM11/CTDP1/CDK9/POLR2H/DDX3X/TRIM21/TARBP2/TBC1D20/CHMP2A/TSG101/CFL1/TOP2B/LGALS1/SUPT4H1/RSF1/GTF2F1/LGALS9/IFIT1/SRPK1/VPS4B/POLR2F/POLR2D/CNOT7/PKN2/ANXA2P2/POLR2K/FMR1/SMC3/NELFCD/CD4/PC/CSF1R/ANXA2/HPN/CCNT1/ADAR/PPIB/POLR2I/NUCKS1/TOP2A	58
BP	GO:0001912	positive regulation of leukocyte mediated cytotoxicity	34/7096	56/18670	0.0004687	0.006478	0.004829	ITGAM/STX7/CD1C/PTPRC/P2RX7/CD1E/LAMP1/CD226/FAM49B/HLA-F/HLA-E/HLA-B/RASGRP1/CD1B/TYROBP/HLA-G/HLA-C/PVR/LAG3/CD1D/IL12RB1/CD1A/ULBP2/CRTAM/VAV1/FADD/AP1G1/HLA-A/NCR3/IL12B/SH2D1A/MICA/IL18RAP/IL23A	34
BP	GO:0070936	protein K48-linked ubiquitination	34/7096	56/18670	0.0004687	0.006478	0.004829	TRIM32/TNFAIP3/BIRC2/SKP2/UBE2Q2/NMI/UBE3A/UBE2K/UBE2D3/UBE2D2/IFI27/FBXO38/UBR5/UBE2E1/RNF146/UBE2A/UBE2G2/RNF115/DTX3L/ARIH2/UBE2E2/UBE2D4/RNF126/RFFL/UBE2C/HACE1/BFAR/ZNRF1/RNF4/RNF5/UBE2G1/TOPORS/RNF216/UBE2B	34
BP	GO:0072528	pyrimidine-containing compound biosynthetic process	34/7096	56/18670	0.0004687	0.006478	0.004829	TYMP/CDS1/UPP1/GPAM/CDS2/CDADC1/CTPS2/AGPAT3/CMPK1/TK1/TPK1/CMPK2/AGPAT4/NME3/NME4/NME1/PRPS1/TYMS/DCK/SHMT1/UCK1/TBPL1/TK2/AGPAT5/DCTD/CTPS1/CAD/CDA/AGPAT1/MTOR/UCKL1/UPP2/DUT/AGPAT2	34
BP	GO:2001242	regulation of intrinsic apoptotic signaling pathway	84/7096	165/18670	0.0004786	0.006601	0.004921	S100A9/S100A8/BMF/TRIM32/CDKN2D/SKIL/PINK1/SOD1/ERP29/PTPN2/TMBIM6/PTGS2/PMAIP1/BCL2A1/MIF/SIAH1/FBXW7/ACKR3/CD44/BCAP31/CD74/PTPMT1/NUPR1/CXCL12/FIS1/HIF1A/WFS1/HSPB1/MAPK7/PTTG1IP/HNRNPK/TMEM161A/NDUFS3/MCL1/HTRA2/NCK1/ENO1/ARHGEF2/CLU/SIRT1/SFPQ/ELL3/LCK/CYLD/LRRK2/PLAUR/FLCN/DDX3X/MUC1/VNN1/BCL2L11/TXNDC12/SERINC3/NACC2/IVNS1ABP/MMP9/BCL2/BAX/NOC2L/SGMS1/CREB3/PDX1/VDAC2/YBX3/DNM1L/NFE2L2/RRM2B/MDM2/TAF9B/BAD/SNAI1/BCLAF1/RAD9A/DNAJA1/HYOU1/MSX1/GPX1/TRIAP1/DAPK2/BAG5/BCL2L2/ATAD5/FIGNL1/DDIAS	84
BP	GO:0031330	negative regulation of cellular catabolic process	127/7096	264/18670	0.0004802	0.006608	0.004927	MYD88/HTR2B/CBFA2T3/BMF/NAMPT/ATP2B4/ATG7/PINK1/FBP1/CTSA/ZFP36/SLC11A1/TSC1/STAT3/LRIG2/TIMP2/RNF41/TOB1/FEZ2/DDRGK1/ATRAID/SEC22B/APOC1/LAMP3/HFE/FHIT/HMOX1/NUPR1/RYBP/SECISBP2/CST3/THRAP3/PAIP1/CHMP4B/CSNK2A2/ALAD/HGF/SGTA/LEP/ZKSCAN3/TAB3/NAF1/MCL1/HTRA2/PTPN22/QSOX1/KLHL22/NMNAT1/OPHN1/DFFA/FURIN/DHX9/SDCBP/UBE2J1/PML/ACACB/UCHL5/UBE2G2/LRRK2/EIF4G2/PPARGC1A/TIMP4/PTK2/SLC25A12/WDR6/PHF23/MYOG/HNRNPC/PFKFB1/BCL2/MAPKAPK2/HDAC4/TIMP1/HNRNPA0/MGAT3/MTMR2/FOXK2/USP30/HNRNPD/YBX3/KLHL40/DDIT4/CPTP/RRAGA/DERL2/LAPTM4B/YOD1/PPARA/USP7/ANXA2P2/MAP1A/WNT1/PSEN1/FMR1/SMCR8/EIF4G1/TREM2/DAP/UBXN1/VIP/OGT/HP/MTMR9/DAPL1/SCFD1/HSP90AB1/CLEC16A/RNF5/PIK3CG/ANXA2/MTOR/SNCA/BAG5/MET/RGP1/TIRAP/USP19/SMARCC1/NBAS/LZTS1/SYNCRIP/BOLL/TARDBP/ERLEC1/OS9/KDM4A/MIR146A	127
BP	GO:0032731	positive regulation of interleukin-1 beta production	32/7096	52/18670	0.0004867	0.006683	0.004982	NOD2/CLEC7A/WNT5A/AZU1/MNDA/LILRA5/NLRP3/LILRA2/NLRP12/JAK2/P2RX7/EGR1/AIM2/TRIM16/HSPB1/PANX1/TLR4/CASP8/AGER/HMGB1/TYROBP/CASP1/LGALS9/FZD5/TLR8/NLRP1/IFNG/NLRP2/APP/CCL19/MALT1/HMGB4	32
BP	GO:0032481	positive regulation of type I interferon production	44/7096	77/18670	0.0004965	0.006782	0.005056	MYD88/TLR2/IRF7/IRF1/STAT6/STAT1/FLOT1/NFKB1/TICAM1/RELA/LRRFIP1/NFKB2/TLR4/DDX58/PTPN22/XRCC5/PLCG2/DHX9/MMP12/POLR2L/HMGB1/MAVS/POLR2H/DDX3X/IFIH1/HMGB2/POLR1C/ZBP1/POLR2F/POLR3E/TLR8/POLR2K/RIOK3/XRCC6/TRIM15/TLR3/ZBTB20/POLR3F/POLR3GL/CHUK/ZCCHC3/HMGB4/POLR3K/RNF135	44
BP	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	44/7096	77/18670	0.0004965	0.006782	0.005056	EPAS1/RBPJ/PSMB9/PSMB8/EGR1/PSMA5/PSMD11/PSME1/HIGD1A/HIF1A/PSMB10/PSMA1/PSMA4/VEGFA/EGLN1/PSMB1/PSMC4/PSMD13/PSMB3/HIF1AN/EGLN3/CITED2/PSMB5/PSMD6/PSMC3/PSME3/PSMC6/UBC/ARNT/NFE2L2/PSMC1/CUL2/PSMD8/PSMA2/BACH1/PSMC5/PSMC2/PSMB2/PSMD4/RBX1/PSMD1/PSMB4/PSMD9/PSMD3	44
BP	GO:0032648	regulation of interferon-beta production	30/7096	48/18670	0.0004975	0.006782	0.005056	TLR2/IRF7/IRF1/FLOT1/LILRB1/TICAM1/REL/NMI/TLR4/DDX58/TRAF3/CACTIN/RELB/DHX9/MAVS/DDX3X/IFIH1/HMGB2/YY1/TLR8/RIOK3/NLRX1/TLR3/TRAF3IP1/ZBTB20/POLR3F/RNF216/TIRAP/NLRC3/RNF135	30
BP	GO:0042269	regulation of natural killer cell mediated cytotoxicity	28/7096	44/18670	0.0004984	0.006782	0.005056	SERPINB9/LAMP1/LILRB1/CD226/LEP/HLA-F/HLA-E/CLEC12B/RASGRP1/PIK3R6/CRK/HLA-G/PVR/LAG3/LGALS9/ULBP2/CRTAM/VAV1/KIR2DL4/AP1G1/HAVCR2/NCR3/SERPINB4/IL12B/SH2D1A/MICA/NCR1/IL18RAP	28
BP	GO:0002715	regulation of natural killer cell mediated immunity	29/7096	46/18670	0.0004994	0.006782	0.005056	SERPINB9/LAMP1/LILRB1/CD226/LEP/HLA-F/HLA-E/CLEC12B/RASGRP1/PIK3R6/CRK/HLA-G/CD96/PVR/LAG3/LGALS9/ULBP2/CRTAM/VAV1/KIR2DL4/AP1G1/HAVCR2/NCR3/SERPINB4/IL12B/SH2D1A/MICA/NCR1/IL18RAP	29
BP	GO:0035710	CD4-positive, alpha-beta T cell activation	51/7096	92/18670	0.0005002	0.006782	0.005056	PTGER4/NFKBIZ/ANXA1/CD55/ARG2/STAT6/STAT3/BCL6/NLRP3/SH3RF1/SMAD7/LY9/IL4R/CBFB/BATF/FUT7/IL18R1/SOCS5/TCIRG1/SEMA4A/ZBTB7B/RELB/RSAD2/NFKBID/AGER/HMGB1/IL6/IL12RB1/CD274/LGALS9/HLX/IL18/TNFSF4/SOCS1/RORA/IFNG/ATP7A/IL12B/PRKCZ/CD80/TBX21/MTOR/PRKCQ/FOXP1/GPR183/CD83/CCL19/MALT1/TWSG1/CDH26/IL23A	51
BP	GO:0009142	nucleoside triphosphate biosynthetic process	94/7096	188/18670	0.0005087	0.006883	0.005131	IGF1/CBFA2T3/HK3/LDHA/PINK1/FBP1/PGK1/VPS9D1/STAT3/PFKFB3/NUP62/NUP160/PFKM/PFKP/GAPDH/NUP214/SLC2A6/P2RX7/NUPR1/PGAM1/PKM/GALK1/EIF6/TPI1/ZBTB7A/TGFB1/NUP85/HIF1A/SEH1L/ADK/INSR/ALDOC/NUP43/IMPDH1/CTPS2/ENO1/DNAJC30/ALDOA/AK8/CMPK1/POM121/OGDH/CMPK2/GPI/PFKFB4/PPARGC1A/FLCN/DHTKD1/NME3/SLC25A12/LDHC/NME4/PRKAG2/MYOG/NCOR1/PFKFB1/NUP88/HDAC4/NME1/NUP107/TYMS/FOXK2/DDIT4/PGK2/PFKFB2/ARNT/UCK1/PPARA/NUP93/TBPL1/SLC25A13/PRKAA1/PSEN1/NUP205/ENO2/PID1/SLC4A1/TREM2/CTPS1/CAD/NUP50/IFNG/PRKAG1/OGT/ESRRB/ZBTB20/VCP/ADPGK/UCKL1/TAZ/APP/PFKL/POM121C/AAAS	94
BP	GO:0002475	antigen processing and presentation via MHC class Ib	13/7096	16/18670	0.0005238	0.00706	0.005263	CD1C/TAP2/CD1E/HLA-F/HLA-E/HLA-B/CD1B/HLA-G/HLA-C/CD1D/CD1A/AP3B1/HLA-A	13
BP	GO:0071347	cellular response to interleukin-1	90/7096	179/18670	0.000524	0.00706	0.005263	MYD88/NOD2/KLF2/GBP2/IL1R2/TNIP2/GBP1/PSMB9/CUL1/TFPI/PSMB8/SQSTM1/CEBPB/MAP3K8/EGR1/UBE2N/PSMA5/PSMD11/IRAK3/NFKBIA/VRK2/NFKB1/IL1RAP/PSME1/RELA/IRAK4/HIF1A/PSMB10/PSMA1/PSMA4/TAB3/MAPK13/TRAF6/HYAL2/IKBKG/CACTIN/PSMB1/IL1B/PSMC4/CCL5/PSMD13/PSMB3/CCL7/IL1RN/IL1R1/CHI3L1/IL6/ADAMTS12/PSMB5/PSMD6/OTUD4/PSMC3/CCL13/TAB1/PSME3/CCL8/PSMC6/CD47/YY1/TOLLIP/IL1A/UBC/HYAL3/PLCB1/USP10/CCL20/CCL26/PSMC1/PSMD8/RORA/PSMA2/ST18/MAPK11/PSMC5/PSMC2/PSMB2/PSMD4/CX3CL1/RBX1/CCL19/CHUK/CCL4/PSMD1/PSMB4/PELI2/CCL24/PSMD9/PSMD3/UPF1/MIR146A	90
BP	GO:0006766	vitamin metabolic process	70/7096	134/18670	0.0005405	0.007261	0.005413	VDR/ACP5/RBP1/SLC19A2/MMADHC/CYP27A1/MTHFD2/SLC23A2/SLC25A19/PPARD/PANK2/ACPP/RDH10/ABCD4/MTR/LGMN/FOLR2/SLC2A3/TNF/CD320/AKR1C3/NFKB1/BTD/AKR1A1/CYB5A/MTRR/GCLC/GSTO1/IL1B/RFK/TPK1/PRSS3/MCCC1/KYNU/HAAO/PDZD11/SHMT2/VNN1/MMAB/PCCB/RXRA/MMACHC/CBR3/VKORC1/CYP26B1/CTRB2/SLC46A1/SLC5A6/CYB5R3/FLAD1/LMBRD1/SHMT1/DHFR/AASDHPPT/CLYBL/THTPA/TCN1/CYP27B1/FPGS/SNAI1/IFNG/CTRC/ALDH1L1/CYP26A1/PC/SLC25A32/VNN3/RLBP1/AOX1/FGF23	70
BP	GO:0031348	negative regulation of defense response	116/7096	239/18670	0.0005412	0.007261	0.005413	KLF4/IGF1/FPR2/PTGER4/METRNL/ACP5/SERPINB9/IL1R2/APPL2/GRN/SOCS3/SOD1/ARG2/PTPN2/NLRP3/PPARD/DUSP10/TNFAIP3/NLRC5/FGL2/NLRP12/GSTP1/PTPRC/A2M/IRAK3/SIGLEC10/YTHDF3/NFKB1/APOE/LILRB1/NMI/CHID1/HGF/TNFAIP6/SOCS5/MAPK7/PSMA1/NR1H2/PRKCD/METTL3/HLA-F/MAPKBP1/IL20RB/ABR/HLA-E/CACTIN/C5orf30/CLEC12B/NR1D2/AGER/SAMHD1/LDLR/MMP12/CRK/HLA-G/MFHAS1/SERPING1/ADCY7/CDH5/CD200R1/CR1/BCR/ETS1/WFDC1/CST7/VSIG4/RPS19/CD96/NPLOC4/SEC14L1/ASH1L/MEFV/TARBP2/SIGLEC11/NR1H3/FFAR4/HTRA1/PCBP2/LGALS9/RABGEF1/CNR2/ADA/C1QBP/CNOT7/MUL1/KIR2DL4/PPARA/GPATCH3/RIOK3/APOA1/RORA/HAVCR2/SERPINB4/NLRX1/RB1/IL12B/TRAF3IP1/MICA/GPX1/TYRO3/CX3CL1/PDCD4/TSPAN6/ABCD1/ADAR/TRAFD1/FOXF1/PSMB4/NR1H4/NLRC3/SLAMF8/C1QTNF3/FAM3A/MIR205/APCS/GHRL	116
BP	GO:0002312	B cell activation involved in immune response	42/7096	73/18670	0.0005437	0.007266	0.005417	IL27RA/DLL1/MAD2L2/NOTCH2/STAT6/BCL6/CD40/LFNG/PTPRC/BATF/DOCK10/TGFB1/UNG/PTK2B/SWAP70/TLR4/ABL1/PLCG2/ITM2A/MLH1/PARP3/ERCC1/CLCF1/CCR6/LGALS1/LIG4/ADA/ITFG2/DOCK11/CDH17/TFRC/TNFSF4/EXO1/PLCL2/EXOSC3/GAPT/TBX21/APLF/GPR183/EXOSC6/PAXIP1/ATAD5	42
BP	GO:0031100	animal organ regeneration	42/7096	73/18670	0.0005437	0.007266	0.005417	CDKN1A/SRSF5/CEBPB/GSTP1/HFE/EZH2/HMOX1/CXCL12/ANXA3/PKM/AXL/CSNK2A2/CDK4/TGFB1/HGF/FLT3/IGF2R/RAP1A/CSNK2B/CCND1/SULF2/LCP1/PFKFB1/ATIC/PCNA/PPAT/TYMS/PDX1/PRMT5/EGFR/WNT1/HAMP/APOA1/FPGS/CAD/NR4A3/CCNA2/WDR35/AURKA/PNPT1/BAK1/PTCH1	42
BP	GO:0032649	regulation of interferon-gamma production	55/7096	101/18670	0.0005573	0.007417	0.005529	CCR2/IL27RA/CLEC7A/SLC11A1/WNT5A/CEBPG/CD2/TNF/LILRB1/AXL/CD226/IL18R1/FAM49B/IL20RB/TLR4/PTPN22/HLA-DPB1/HLA-DPA1/PDE4B/HRAS/ABL1/IL1B/RASGRP1/ISG15/HMGB1/IL1R1/SCGB1A1/PDCD1LG2/CD96/CD47/INHBA/IL12RB1/CD274/LGALS9/EBI3/PGLYRP4/FZD5/IRF8/C1QBP/IL18/FADD/CD276/TNFSF4/TLR8/HAVCR2/TXK/TLR3/INHA/TNFRSF13C/IL12B/CD244/CCR7/CD3E/NR1H4/IL23A	55
BP	GO:0046632	alpha-beta T cell differentiation	55/7096	101/18670	0.0005573	0.007417	0.005529	PNP/PTGER4/NFKBIZ/ANXA1/IRF1/STAT6/STAT3/BCL6/NLRP3/SH3RF1/SMAD7/LY9/IL4R/CBFB/BATF/FUT7/IL18R1/SOCS5/SEMA4A/ZBTB7B/RELB/ABL1/RSAD2/NFKBID/HMGB1/ITK/IL6/BCL2/GPR18/IL12RB1/LGALS9/ADA/HLX/IL18/AP3B1/BCL11B/TNFSF4/SOCS1/RORA/IFNG/ATP7A/IL12B/PRKCZ/CD80/TBX21/MTOR/FOXP1/RHOA/GPR183/CD83/CCL19/MALT1/ZBTB16/TNFSF8/IL23A	55
BP	GO:0043488	regulation of mRNA stability	89/7096	177/18670	0.0005593	0.007428	0.005538	MYD88/ZFP36/SLC11A1/VIM/PSMB9/PSMB8/ZC3H14/NUP214/PSMA5/PSMD11/YTHDF3/MOV10/TNPO1/HNRNPR/METTL14/GIGYF2/PSME1/THRAP3/PAIP1/FASTKD1/PSMB10/HSPB1/PSMA1/PSMA4/PRKCD/METTL3/SAMD4B/NPM1/PSMB1/PSMC4/DHX9/DCP2/PSMD13/ZC3H12D/PSMB3/PUM2/PSMB5/PSMD6/PSMC3/SCGB1A1/FTO/HNRNPC/PSME3/XRN1/MAPKAPK2/EXOSC2/PSMC6/HNRNPA0/RNASEL/CSDC2/UBC/EXOSC7/HNRNPD/CPEB3/YBX3/HNRNPM/TBRG4/FMR1/PSMC1/ZFP36L2/EIF4G1/PSMD8/PSMA2/EXOSC9/VIP/EXOSC3/PCID2/SET/PSMC5/PSMC2/PSMB2/PSMD4/MTOR/SAMD4A/EXOSC6/TIRAP/EXOSC8/PSMD1/ROCK2/PSMB4/SYNCRIP/BOLL/TARDBP/PRKCA/PSMD9/PSMD3/EXOSC5/PLEKHN1/UPF1	89
BP	GO:0051403	stress-activated MAPK cascade	136/7096	286/18670	0.0005702	0.007557	0.005634	NOD2/EZR/PTGER4/DUSP1/PINK1/ZFP36/TNIP2/WNT5A/SH2D3C/ZNF622/CUL1/SH3RF1/DUSP10/MAP2K1/MYC/GSTP1/MAP3K8/FAS/UBE2N/DVL2/TNF/ERCC6/NFKB1/ZEB2/MAP3K4/HMGCR/SLAMF1/DUSP3/IRAK4/TAOK3/GADD45B/HGF/PAK1/MAP4K5/PTK2B/PRDX1/LEP/ROR2/TAB3/MAPK13/TRAF6/IKBKG/NCF1/TLR4/PTPN22/TPD52L1/BMP2/IGF1R/VEGFA/HRAS/ARHGEF6/PAFAH1B1/IL1B/DTNBP1/SEMA4C/AGER/MAP3K12/RASGRP1/SDCBP/MDFIC/HMGB1/TNFRSF11A/IL1RN/MFHAS1/DUSP19/MAP4K2/MAP4K3/CYLD/RELL2/SPHK1/NCOR1/MAPK8/TAB1/ADORA2B/EDAR/MAPKAPK2/MAP3K6/MAP4K1/ZMYND11/MLKL/UBC/MAP2K2/MAP3K11/SH3RF3/LGALS9/FZD5/AMBP/BIRC7/MAP3K5/PLCB1/EIF2AK2/EGFR/MUL1/CAV3/TRAF2/FZD4/MAPK1/MAP2K4/MAP3K13/PPEF2/IGBP1/EPHB1/MAPK11/HIPK3/DNAJA1/ANKRD6/ULK4/TLR3/FZD7/MEN1/MAP4K4/GPS1/TRPV4/APP/ERN1/PDCD4/PDCD10/CCL19/TIRAP/NBR1/CHUK/TRAF4/AIDA/WNT7A/CCR7/PRMT1/IL26/DAXX/SERPINF2/TLR6/FZD10/NRK/MAPK9/SASH1/IL37/MAP3K9	136
BP	GO:0021537	telencephalon development	121/7096	251/18670	0.0005813	0.007688	0.005731	NRGN/SLC8A1/RTN4R/ATP2B4/TRA2B/SUN2/SKI/WNT5A/TSC1/SRD5A1/TCTN1/FLNA/MBOAT7/BCL2A1/ATF5/ALK/SLC7A11/EZH2/EPHB2/EXT1/BTBD3/GSK3B/ZEB2/SECISBP2/ZSWIM6/BTG2/CXCL12/ANXA3/CSNK2A2/LRP8/HIF1A/PHACTR1/ARL13B/SRF/NRG1/XRN2/FBXO45/DPCD/EIF2B5/BMP2/CDK5/CASP3/PAFAH1B1/SRGAP2C/NUMB/P2RY12/LRP1/BBS2/CRK/MKKS/LRRK2/ASPM/TSKU/ARX/BBS4/DIXDC1/SYNE2/SRGAP2/MFSD2A/DCLK2/NRP1/DISC1/TRAPPC9/ATIC/BMP4/XRCC1/KDM2B/BAX/NRP2/ID2/NME1/PEX13/NDEL1/INHBA/DAB1/RTN4RL1/ZDHHC16/BCAN/UQCRQ/LPAR1/HES1/KDM6B/CDK5R2/PLCB1/EGFR/BCL11B/SLIT2/KAT2A/PSEN1/YWHAE/RTN4RL2/BAD/HTR5A/NUMBL/PLXNA3/NR4A3/KIF5B/TMEM14B/EIF2B3/GNG12/PHLPP2/NR2E1/RELN/CSF1R/CEP120/RHOA/RTN4/EFNA2/PAX5/EFHC1/EZH1/LMX1A/FGF13/SLC8A3/AGTPBP1/SMO/SHANK3/LHX6/AVPR2/KIF14/NTRK2	121
BP	GO:0032438	melanosome organization	18/7096	25/18670	0.0005858	0.007715	0.005752	BLOC1S2/HPS4/ZEB2/TRAPPC6A/HPS1/ASIP/DTNBP1/BLOC1S6/RAB32/RAB38/BLOC1S3/GPR143/KIF13A/BLOC1S1/BLOC1S4/AP3B1/AP1G1/AP1M1	18
BP	GO:0090025	regulation of monocyte chemotaxis	18/7096	25/18670	0.0005858	0.007715	0.005752	FPR2/CCR2/DUSP1/LYN/LGMN/PLA2G7/CXCL10/CXCL12/AIF1/CCL5/HMGB1/MOSPD2/SERPINE1/CREB3/SLIT2/GREM1/SLAMF8/S100A14	18
BP	GO:0070227	lymphocyte apoptotic process	40/7096	69/18670	0.0005927	0.007791	0.005808	TSC22D3/PIP/BCL10/LYN/WNT5A/ARG2/BCL6/SLC46A2/MIF/P2RX7/ADAM8/CD74/TNFRSF21/PRELID1/IL7R/DOCK8/HIF1A/CLC/SLC39A10/IDO1/NFKBID/DFFA/CCL5/IRS2/FNIP1/BCL2L11/BMP4/BAX/NOC2L/CD3G/CD274/LGALS9/BIRC7/ADA/FADD/PTCRA/PRKCQ/FOXP1/BAK1/PDCD1	40
BP	GO:0045732	positive regulation of protein catabolic process	105/7096	214/18670	0.0005966	0.00781	0.005822	CBFA2T3/TRIM32/EZR/TMTC3/ATG7/SNX1/WWP1/WNT5A/BARD1/OAZ2/RNF41/SMAD7/TNFAIP3/KEAP1/DDRGK1/FBXW7/CTSC/SEC22B/RNF139/BCAP31/ADAM8/TNF/NUPR1/APOE/GSK3B/MAGEF1/RNF19B/FBXL5/EDEM1/RDX/SGTA/ZFAND2A/SOCS5/PTK2B/CSNK1D/PTTG1IP/RNF217/DDB1/OAZ3/CEBPA/PLK2/ANKIB1/GCLC/IL1B/PSMC4/FURIN/UQCC2/LDLR/LRP1/CLU/SNX33/EDEM2/LRRK2/SUMO1/STX5/PTK2/HSPBP1/CSNK1A1/CSNK1E/RNFT1/ARIH2/PLK3/DISC1/UBQLN2/ATG4B/NEDD4/TIPARP/CDKN1B/TRIB2/BBS7/DET1/RHBDD3/NKD2/KLHL40/STUB1/DTL/NFE2L2/ATXN3/WWP2/ASB11/CAV3/BAG2/ADAM9/DVL1/PSEN1/FMR1/MDM2/MSN/PSMC1/TREM2/IFNG/VIP/CUL4B/RNF185/PSMC2/VCP/AURKA/SNX9/RBX1/LPCAT1/KCNE2/CHFR/GJA1/PACSIN3/MAPK9	105
BP	GO:1903050	regulation of proteolysis involved in cellular protein catabolic process	105/7096	214/18670	0.0005966	0.00781	0.005822	CBFA2T3/TMTC3/PINK1/SMAD7/KEAP1/DDRGK1/FBXW7/CTSC/RNF139/LAMP3/BCAP31/HFE/RAD23B/FHIT/NUPR1/RYBP/APOE/GSK3B/PSME1/MAGEF1/RNF19B/EDEM1/CSNK2A2/UBE3A/UBE2K/ALAD/SGTA/ZFAND2A/SOCS5/PTK2B/CSNK1D/LATS1/RNF217/CEBPA/PLK2/ANKIB1/GCLC/OPHN1/PSMC4/SDCBP/UBE2J1/ARAF/PML/CLU/UCHL5/UBE2G2/EDEM2/LRRK2/SUMO1/GLMN/PTK2/HSPBP1/CSNK1A1/CSNK1E/RNFT1/ARIH2/PLK3/PSME3/DISC1/UBQLN2/TRIB2/PRKACA/BBS7/DET1/NKD2/KLHL40/DERL2/STUB1/NFE2L2/ATXN3/COMMD1/NFE2L1/YOD1/CAV3/BAG2/USP7/DVL1/MAP1A/WNT1/PSEN1/FMR1/MDM2/PSMC1/TREM2/UBXN1/OGT/RNF185/HSP90AB1/CLEC16A/FOXF2/PSMC2/GPX1/VCP/AURKA/RBX1/BAG5/USP19/SMARCC1/KCNE2/CHFR/WNT10B/ERLEC1/OS9/MAPK9/RHBDF1	105
BP	GO:0071356	cellular response to tumor necrosis factor	138/7096	291/18670	0.0006016	0.007859	0.005859	CRHBP/ASAH1/KLF2/TRIM32/GBP2/ZFP36/FABP4/GBP1/CD58/PTPN2/PSMB9/TNFRSF14/TNFAIP3/CD40/PSMB8/BIRC2/CIB1/ACTN4/STAT1/JAK2/GSTP1/PSMA5/TNF/PSMD11/NFKBIA/TNFRSF21/NFKB1/PSME1/AIM2/RELA/PSMB10/PTK2B/TXNDC17/PSMA1/TNFSF13B/PSMA4/HYAL2/SPPL2A/IKBKG/TRAF3/CEBPA/CARD14/TNFRSF12A/CACTIN/CASP8/PSMB1/PSMC4/CCL5/DHX9/ARHGEF2/PSMD13/SPATA2/TNFRSF11A/TRADD/PSMB3/CCL7/TNFRSF18/RBCK1/SIRT1/CHI3L1/ADAMTS12/CYLD/PPARGC1A/PSMB5/PSMD6/EDA/MIR34A/PSMC3/SPHK1/CCL13/MYOG/PSME3/EDAR/CCL8/PSMC6/INPP5K/HDAC4/BIRC3/SGMS1/CASP1/PRPF8/RFFL/CYBA/HYAL3/YBX3/KRT8/HIPK1/MAP3K5/TRAF1/PIAS3/NFE2L2/BRCA1/ADAM17/TRAF2/CCL20/CASP4/TNFRSF13B/CCL26/TNFSF4/CPNE1/KAT2A/TAX1BP1/HAMP/DCSTAMP/MAPK1/PID1/APOA1/PSMC1/ZFP36L2/TNFRSF4/PSMD8/RORA/PSMA2/ST18/CLDN18/TNFSF18/TNFRSF25/TNFRSF13C/WDR35/PSMC5/PSMC2/PSMB2/PSMD4/LIMS1/CX3CL1/CLIP3/ZFAND6/CCL19/CHUK/CCL4/PSMD1/TNFSF8/PSMB4/CCL24/NR1H4/PSMD9/PSMD3/FOXO3	138
BP	GO:0010507	negative regulation of autophagy	47/7096	84/18670	0.0006196	0.008078	0.006023	HTR2B/BMF/NAMPT/ATG7/PINK1/CTSA/TSC1/STAT3/RNF41/FEZ2/SEC22B/HMOX1/NUPR1/CHMP4B/HGF/LEP/ZKSCAN3/TAB3/MCL1/HTRA2/PTPN22/QSOX1/KLHL22/LRRK2/EIF4G2/PTK2/WDR6/PHF23/BCL2/FOXK2/USP30/CPTP/RRAGA/SMCR8/EIF4G1/TREM2/DAP/MTMR9/DAPL1/SCFD1/CLEC16A/RNF5/MTOR/SNCA/MET/LZTS1/KDM4A	47
BP	GO:0061572	actin filament bundle organization	80/7096	157/18670	0.000621	0.008081	0.006024	S100A10/EZR/PTGER4/DPYSL3/PLS1/STMN1/FHOD1/TSC1/ARAP1/SORBS3/ITGB5/NEDD9/FLNA/RHOC/S1PR1/ACTN4/RGCC/SPIRE1/SLC9A1/ARHGEF10L/RND3/LIMA1/EVL/RDX/PFN1/ARRB1/PAK1/MARCKS/PHACTR1/PTK2B/SWAP70/SRF/ACTN1/BAIAP2/ABL1/AIF1/PPM1F/MKKS/RAC1/CORO1B/ARHGAP6/BBS4/LIMCH1/ZYX/LCP1/NRP1/FSCN3/TPM1/INPP5K/CD47/PLS3/ADD3/PLEK/SHANK1/RHOF/LPAR1/DMTN/PXN/CLASP2/HSP90B1/FSCN1/APOA1/TGFB3/SYNPO2L/TACSTD2/TMEFF2/MTOR/RHOA/CX3CL1/ITGB1BP1/MET/SHROOM1/ESPNL/WAS/ROCK2/ASAP3/SHANK3/SERPINF2/ALMS1/SYNPO	80
BP	GO:0071222	cellular response to lipopolysaccharide	101/7096	205/18670	0.0006259	0.008128	0.006059	NOD2/CX3CR1/TLR2/LILRB2/BCL10/SBNO2/LYN/CD55/ZFP36/TNIP2/WNT5A/VIM/HCK/CAPN2/NLRP3/PPARD/TFPI/TNFAIP3/MIF/LY96/LY86/PPBP/LILRA2/CXCL9/CEBPB/SCARB1/GSTP1/CXCL11/TNF/PAF1/NFKBIA/CXCL10/NFKB1/LILRB1/PLAA/TICAM1/RELA/AXL/CDK4/TGFB1/PTAFR/CD36/NR1H2/TRAF6/CXCL13/TLR4/PTPN22/PDE4B/CACTIN/ABL1/NFKBIB/ABCA1/IL1B/CCL5/HMGB1/CMPK2/IL1RN/IL6/PPARGC1A/CCR5/BCR/PDCD1LG2/AKAP8/MAPK8/SERPINE1/HMGB2/NR1H3/SGMS1/TNIP3/CASP1/PRPF8/CD274/IRF8/IL18/ADAM9/TNFSF4/HAMP/MAPK1/SIGIRR/HAVCR2/LACRT/CTSG/LBP/IL12B/MTDH/CD80/HDAC5/PLSCR4/RHOA/CDC73/CX3CL1/PDCD4/MALT1/NR1H4/PRKCA/CXCL6/MEF2C/UPF1/SASH1/IL37/MIR146A	101
BP	GO:0009101	glycoprotein biosynthetic process	162/7096	348/18670	0.000628	0.008138	0.006067	IGF1/HS3ST2/VCAN/TMTC3/PGM3/EXTL2/CHSY1/NDST2/HS2ST1/MCFD2/MGAT2/DAD1/B3GNT8/VEGFB/CHP1/MGAT5/MAN1C1/POMGNT2/LFNG/GALNT14/AGO2/IL15/FUT4/SOAT1/EXT2/EXT1/CHST13/FUT7/FAM20B/TET2/MGAT4B/ITM2B/B3GNT2/MAN2A2/STT3A/NAGPA/B4GALT6/ARFGEF1/CSGALNACT1/POGLUT1/ALG2/KRTCAP2/B3GNT5/TRAK2/CSPG4/OST4/PMM2/ST6GALNAC4/CYTL1/ITM2A/UBE2J1/ST3GAL2/GALNT7/XYLT1/LMF1/CHST11/SLC35D1/MUC2/B3GALT6/FKRP/GLCE/ALG6/UBE2G2/SDF2L1/DPY19L4/DPM1/GALNT6/CHST14/TMTC2/BACE2/SERP1/GCNT1/XYLT2/RPN2/GALNT12/DOLK/AATF/MUC1/GALNT10/STT3B/BCL2/TNIP1/NUDT14/ALG12/ALG10/MGAT3/GAL3ST4/MAN1B1/NDST1/CSGALNACT2/ASGR2/HS3ST1/LMAN1/DOLPP1/FUT6/B4GALT5/ST8SIA4/BCAN/MGAT5B/ALG13/ABCA7/MAN1A2/MOGS/HS3ST3B1/POMT1/PLCB1/TUSC3/TMEM258/SLC35C1/NUS1/DHDDS/GALNT9/SRD5A3/ST6GALNAC5/XXYLT1/GFPT1/POMT2/PSEN1/DPM3/B3GNT4/GGTA1P/ST3GAL1/DPY19L2/TCF7L2/MUC6/NECAB3/OGT/ATP7A/CHST12/TRAK1/GCNT2/ST6GALNAC3/B3GAT3/HBEGF/MUCL1/ST6GALNAC6/COG7/HS3ST6/ASGR1/VCP/C1GALT1/B3GALT5/GFPT2/B4GALT1/GALNT1/CCL19/ALG14/EDEM3/CCR7/BMPR1B/ST8SIA1/DDOST/ST3GAL5/DPAGT1/DPY19L2P2/ALG8/TET1/ALG3/GALNT15/CHST7/ACOT8/BMPR2	162
BP	GO:0036336	dendritic cell migration	19/7096	27/18670	0.0006525	0.008422	0.006279	CCR2/NLRP12/DOCK8/CCL5/HMGB1/TRPM4/TRPM2/CXCR1/CCR5/CCR6/LGALS9/CALR/C1QBP/CXCR2/PIK3CG/GPR183/CCL19/CCR7/SLAMF8	19
BP	GO:0048143	astrocyte activation	19/7096	27/18670	0.0006525	0.008422	0.006279	FPR2/GRN/TNF/MIR142/IL1B/AGER/LDLR/LRP1/TTBK1/IL6/BACE2/CNTF/IFNGR1/EGFR/PSEN1/TREM2/IFNG/APP/SMO	19
BP	GO:0007409	axonogenesis	212/7096	468/18670	0.0006543	0.008428	0.006283	RTN4R/FN1/FYN/VASP/EZR/RAC2/SIPA1L1/DPYSL2/SKIL/STMN1/NR4A2/MAP1S/DOK2/WNT5A/C9orf72/SEMA4B/TCTN1/SPP1/SLITRK4/RAB11A/FEZ2/PITPNA/MAP2K1/SIAH1/ULK2/LAMB2/FLOT1/ALCAM/ALS2/UCHL1/VCL/EPHB2/ARHGDIA/IFRD1/S100A6/EXT1/APOE/GSK3B/ZEB2/ZSWIM6/GAB1/LYPLA2/CXCL12/PTPRO/PLXNB2/EVL/ACTB/TWF2/PPP3CB/STXBP1/SIN3A/B3GNT2/PAK1/MEGF8/RANBP9/MAPK7/PLXNC1/ROBO3/PDLIM7/SRF/ATL1/NCAM1/SCN1B/B4GALT6/BAIAP2/FBXO45/SEMA4A/ITGA4/ADARB1/VEGFA/USP9X/CDK5/TNFRSF12A/CYFIP2/TRAK2/ABL1/PAFAH1B1/TUBB3/OPHN1/GDI1/NEXN/S100B/NUMB/SEMA4C/SHC1/SEMA4D/LRP1/CREB1/EFNB1/RAB8A/NPTN/BMP7/AFG3L2/RAC1/SPTBN1/EGR2/IRS2/DCC/EPHA8/CYFIP1/MYCBP2/KLF7/DOK1/EPHA10/TSKU/ADCY1/PTK2/ARX/GRB10/SEMA6B/PLXNA1/GFRA2/NRP1/DISC1/SEMA3B/PLXND1/BCL2/DNM2/GFRA4/L1CAM/NRP2/GFRA3/PIK3CD/MARK2/CNTN4/NTNG2/TOP2B/LPAR3/IST1/NDEL1/SYNGAP1/DAB1/OLFM1/GRB2/GRB7/UNC5B/B4GALT5/WDR36/SEMA5A/PARD6B/FSTL4/UNC5C/ULK1/AMIGO1/BCL11B/SLIT2/DVL1/MAP1A/LAMA2/PSEN1/SEMA5B/RAB3A/MAPK1/CHRNB2/SHOX2/RPL24/POU4F3/MAP3K13/EPHB1/RUFY3/NUMBL/PLXNA3/SPTA1/NR4A3/LLGL1/RET/TRAK1/HSP90AB1/SPTBN2/CNP/PLXNA2/ENAH/LGR6/NR2E1/RELN/CSF1R/PRKCQ/CHODL/RHOA/BRSK1/APP/RTN4/DAG1/SHC3/EFNA2/PTPRZ1/CRABP2/LMX1A/FGF13/LRP4/WNT7A/PICALM/BMPR1B/SMO/BOC/SHANK3/PRKCA/KEL/PTCH1/MACF1/DPYSL5/TRPV2/NTRK2/PTPRM/PIK3CB/TRIM46/EFNA3/LHX9/BMPR2/CCKAR/LAMA1/SLIT3	212
BP	GO:0009895	negative regulation of catabolic process	145/7096	308/18670	0.0006566	0.008441	0.006293	MYD88/HTR2B/CBFA2T3/FYN/BMF/NAMPT/ATP2B4/ATG7/PINK1/MAD2L2/FBP1/CTSA/ZFP36/SLC11A1/TSC1/STAT3/LRIG2/TIMP2/RNF41/FLNA/TOB1/FEZ2/DDRGK1/ATRAID/SEC22B/APOC1/LAMP3/HFE/TNF/IRAK3/FHIT/HMOX1/NUPR1/RYBP/SECISBP2/HMGCR/CST3/THRAP3/RELA/PAIP1/CHMP4B/CSNK2A2/ALAD/HGF/SGTA/LEP/ZKSCAN3/TAB3/NRG1/BANP/NAF1/MCL1/HTRA2/PTPN22/QSOX1/KLHL22/NMNAT1/OPHN1/IL1B/DFFA/FURIN/DHX9/SDCBP/UBE2J1/PML/ACACB/UCHL5/UBE2G2/LRRK2/EIF4G2/PPARGC1A/MYCBP2/TIMP4/PTK2/CRTC3/SLC25A12/WDR6/PHF23/MYOG/HNRNPC/PFKFB1/BCL2/MAPKAPK2/HDAC4/TIMP1/HNRNPA0/MGAT3/MTMR2/FOXK2/USP30/AZIN1/HNRNPD/YBX3/KLHL40/DDIT4/CPTP/RRAGA/DERL2/GRIN2C/LAPTM4B/EGFR/YOD1/PPARA/USP7/ANXA2P2/MAP1A/WNT1/PRKAA1/PSEN1/FMR1/SMCR8/EIF4G1/TREM2/DAP/UBXN1/VIP/OGT/HP/MTMR9/PIN1/DAPL1/SCFD1/HSP90AB1/CLEC16A/RNF5/PIK3CG/ANXA2/MTOR/SNCA/BAG5/AZIN2/MET/RGP1/TIRAP/USP19/SMARCC1/NBAS/LZTS1/SYNCRIP/BOLL/TARDBP/ERLEC1/OS9/KDM4A/MIR146A	145
BP	GO:0030705	cytoskeleton-dependent intracellular transport	90/7096	180/18670	0.0006607	0.008478	0.00632	APBA1/TUBA1A/SUN2/MAP1S/SOD1/BLOC1S2/ACTN4/UCHL1/IFT172/LAMP1/TNPO1/IFT57/KIF3B/CCDC88B/KIFAP3/HIF1A/HSPB1/PCM1/MYO5A/DYNLL2/CEP131/BICD2/IFT80/AP3M2/TRAK2/PURA/PAFAH1B1/DTNBP1/CLN3/RHOT2/WDR19/RASGRP1/BLOC1S6/KIF4A/BBS12/SFPQ/HOOK2/IFT46/CCDC88A/RPGR/MYO1C/IFT52/FLOT2/BICD1/SYNE2/ARL8A/MAK/HOOK3/HSPB11/TMEM201/TUBA1C/BLOC1S3/COPG2/DYNC2LI1/NDEL1/KIF13A/DYNLRB1/DYNLRB2/BLOC1S1/BLOC1S4/LCA5/PEX14/AP3B1/MAP1A/FMR1/IFT20/KIF17/WDR60/TUBA1B/MYO10/KIF1B/AP3M1/KIF5B/TRAK1/IFT22/WDR35/TRAF3IP1/PRKCZ/MREG/KIF1C/APP/IFT74/TRIM58/UXT/KLC3/TTC30B/MGARP/IFT81/ARL8B/TRIM46	90
BP	GO:0046474	glycerophospholipid biosynthetic process	106/7096	217/18670	0.0006884	0.008815	0.006572	FPR2/HTR2B/LPCAT2/SLC27A1/CDS1/PLA2G12A/CHPT1/DGKA/CAPN2/GPAM/PLSCR1/PLEKHA1/MTMR12/PIGV/CDS2/PIGP/PTDSS2/PTPMT1/PIGK/PIK3R3/PTPN13/PLD1/PNPLA3/SACM1L/CSNK2A2/PIGN/STARD10/SYNJ1/PITPNM1/DDHD1/FIG4/AGPAT3/PLCG2/PIK3R6/CSNK2B/PIGF/SYNJ2/STARD7/CDIPT/FABP3/PIGB/DPM1/OCRL/PDGFB/ABHD3/AGPAT4/GPAA1/SH3YL1/RAB38/ATM/ARF1/CRLS1/PIGM/MFSD2A/PLEKHA8/SBF1/LCAT/MTMR4/MPPE1/INPP5K/MTMR6/PIK3CD/PI4K2A/RAB5A/PIGQ/ACP6/MTMR2/INPP5F/PDGFA/FAR1/PIGO/CHKA/PIGH/FABP5/AGK/AGPAT5/PLD2/CPNE1/DPM3/MTMR3/PLEKHA3/APOA1/PLA2G6/PIGT/GNPAT/CPNE3/MTMR9/SLC44A2/PIK3CG/AGPAT1/PIP5K1B/CHAT/TAZ/VAC14/LPCAT1/CHKB/PGS1/AGPAT2/PGAP3/INPPL1/NR1H4/ARF3/PGAP1/PIK3CB/IMPA1/PI4KB	106
BP	GO:0007250	activation of NF-kappaB-inducing kinase activity	14/7096	18/18670	0.0006984	0.008891	0.006628	TNFRSF10A/ZFP91/TRAF6/CARD14/CHI3L1/TNFRSF10B/TRAF2/TLR3/CARD10/COPS8/MALT1/TIRAP/TRAF4/TLR6	14
BP	GO:0043555	regulation of translation in response to stress	14/7096	18/18670	0.0006984	0.008891	0.006628	PPP1R15A/RPS6KA3/ATF4/RBM4/NCK1/NPM1/PPP1R15B/EIF2S1/IMPACT/PPP1CA/EIF2AK2/EIF2AK1/EIF2AK4/SESN2	14
BP	GO:0070233	negative regulation of T cell apoptotic process	14/7096	18/18670	0.0006984	0.008891	0.006628	TSC22D3/PIP/ARG2/SLC46A2/IL7R/DOCK8/HIF1A/IDO1/CCL5/BMP4/ADA/FADD/PTCRA/PRKCQ	14
BP	GO:0030258	lipid modification	115/7096	238/18670	0.000703	0.008931	0.006658	PDK4/ALDH3A2/APPL2/SOCS3/HADHB/POR/STARD4/DGKA/PPARD/HADH/ADIPOR1/ACAA1/SIRT4/PHYH/APOC1/PLA2G7/SOAT1/IMPAD1/CISH/SCP2/INPP1/APOE/PIK3R3/ETFA/SACM1L/CPT2/DGKD/IP6K1/AUH/ABCD3/SOCS5/LEP/SYNJ1/ECH1/ACADM/ACADS/TTC7A/DECR1/SOCS6/FAM126A/LAMTOR1/ACOX1/ETFDH/ECI2/ST3GAL2/PIK3R6/SLC27A2/HSD17B4/ACACB/ACOX2/SYNJ2/DGAT2/FABP3/OCRL/IRS2/SOCS7/BDH2/PPARGC1A/DECR2/MLYCD/APOA5/SPHK1/PRKAG2/LCAT/ECI1/MTMR4/INPP5K/IMPA2/MTMR6/PIK3CD/ABCG1/B4GALNT1/PI4K2A/ETFB/PEX13/TYSND1/MTMR2/CPT1A/EHHADH/INPP5F/ACADVL/HADHA/PPARA/SLC35C1/AGK/ACAA2/ADIPOR2/PRKAA1/MTMR3/APOA1/SOCS1/ACOX3/DGKG/CERK/NR4A3/MTMR9/PIK3CG/SLA2/CROT/MTOR/PIP5K1B/ABCD1/HACL1/SOCS2/INPPL1/ADH7/CYP2C8/SESN2/EFR3A/HAO1/INPP5A/PIK3CB/ACOT8/IMPA1/PI4KB	115
BP	GO:0030010	establishment of cell polarity	70/7096	135/18670	0.0007092	0.008993	0.006704	MPP5/ARF6/WNT5A/FAM89B/RAP1B/RNF41/CYTH1/SPDL1/GSK3B/DOCK8/PAK1/MAP4/PTK2B/ARFGEF1/UBXN2B/PAFAH1B1/CDK5RAP2/OPHN1/SAPCD2/NSFL1C/ARHGEF2/CRK/SH3BP1/CDH5/FLOT2/SNX27/KRIT1/PTK2/MYH9/BCCIP/NDC80/WDPCP/CYP26B1/BCAS3/MARK2/KIF20B/CFL1/KANK1/SIPA1L3/NDEL1/ZW10/HES1/SPRY1/MOS/GPSM2/JAM3/MPP7/SPRY2/FSCN1/MSN/WEE1/FRMD4A/EPHB1/RUFY3/LLGL1/CENPA/HSP90AB1/PRKCZ/MISP/RHOA/BRSK1/CCL19/AMOTL1/FOXF1/FGF13/WNT7A/CCR7/ROCK2/WWC1/LAMA1	70
BP	GO:0021885	forebrain cell migration	35/7096	59/18670	0.0007165	0.009045	0.006743	SUN2/MBOAT7/CXCL12/AXL/ARL13B/SRF/NRG1/FBXO45/CDK5/PAFAH1B1/SRGAP2C/P2RY12/LRRK2/ARX/DIXDC1/SYNE2/SRGAP2/NRP1/DISC1/NRP2/PEX13/NDEL1/DAB1/CDK5R2/EGFR/SLIT2/PSEN1/NR2E1/RELN/RHOA/TYRO3/RTN4/EFHC1/FGF13/LHX6	35
BP	GO:0032732	positive regulation of interleukin-1 production	35/7096	59/18670	0.0007165	0.009045	0.006743	NOD2/CLEC7A/WNT5A/AZU1/MNDA/LILRA5/NLRP3/LILRA2/NLRP12/JAK2/P2RX7/EGR1/AIM2/TRIM16/HSPB1/PANX1/TLR4/CASP8/AGER/HMGB1/TYROBP/HDAC2/CASP1/LGALS9/FZD5/TLR8/NLRP1/HAVCR2/IFNG/NLRP2/APP/CCL19/MALT1/HMGB4/IGHD	35
BP	GO:0046660	female sex differentiation	61/7096	115/18670	0.0007176	0.009045	0.006743	WNT5A/SOD1/RETN/SRD5A1/PLEKHA1/KITLG/LFNG/CEBPB/NUPR1/AXL/UBE3A/ARRB1/CTNNA1/SGPL1/ZNF830/LEP/INSR/PTX3/EIF2B5/HSPA5/VEGFA/CASP3/IDH1/SIRT1/ACVR1B/ATM/IMMP2L/BCL2/BAX/TIPARP/CASP2/NUP107/INHBA/HYAL3/MMP14/FZD4/SLIT2/CCDC182/FANCG/MERTK/TAF4/LHFPL2/FSHR/INHA/KMT2B/TYRO3/FANCA/ZFP42/BAK1/EIF2B2/NRIP1/BMPR1B/ADCYAP1R1/AMHR2/MMP19/WT1/RBP4/FOXO3/LHX9/SLIT3/STRA6	61
BP	GO:0071216	cellular response to biotic stimulus	114/7096	236/18670	0.0007496	0.00943	0.007031	NOD2/TLR1/CX3CR1/TLR2/LILRB2/CLEC7A/BCL10/SBNO2/LYN/CD55/ZFP36/TXNIP/TNIP2/WNT5A/VIM/HCK/CAPN2/NLRP3/PPARD/TFPI/TNFAIP3/MIF/LY96/LY86/PPBP/LILRA2/CXCL9/CEBPB/SCARB1/GSTP1/CXCL11/TNF/PAF1/NFKBIA/CXCL10/NFKB1/GSK3B/LILRB1/PLAA/TICAM1/RELA/AXL/CDK4/TGFB1/PTAFR/WFS1/CD36/NR1H2/TRAF6/CXCL13/TLR4/PTPN22/HSPA5/PDE4B/CACTIN/ABL1/NFKBIB/ABCA1/IL1B/CCL5/HMGB1/CMPK2/IL1RN/PPP1R15B/IL6/PPARGC1A/CCR5/BCR/PDCD1LG2/AKAP8/BCL2L11/MAPK8/SERPINE1/HMGB2/NR1H3/SGMS1/TNIP3/CASP1/PRPF8/CD274/FZD5/ZMPSTE24/IRF8/IL18/ADAM9/TNFSF4/HAMP/MAPK1/SIGIRR/TREM2/HAVCR2/LACRT/CTSG/LBP/IL12B/MTDH/CD80/HDAC5/PLSCR4/RHOA/CDC73/CX3CL1/PDCD4/MALT1/TIRAP/NR1H4/PRKCA/TLR6/CXCL6/MEF2C/UPF1/SASH1/IL37/MIR146A	114
BP	GO:0009408	response to heat	88/7096	176/18670	0.0007532	0.009457	0.00705	IGF1/MYOF/CDKN1A/LYN/IER5/SOD1/HSPA6/NUP62/NUP160/PTGS2/LRP11/NUP214/DNAJA4/HMOX1/CXCL10/IGFBP7/GSK3B/CXCL12/DNAJB1/NUP85/HSF2/SEH1L/RPA1/HTRA2/EIF2B5/NUP43/HSF4/HSPA5/RBBP7/GCLC/DNAJC2/POM121/SIRT1/EIF2S1/MLST8/FGF1/DNAJB6/SUMO1/PTGES3/ATM/DNAJC7/DNAJB4/HDAC2/HSBP1/MAPKAPK2/NUP88/PRKACA/NUP107/IL1A/AKT1S1/CAMK2A/POLR2D/STUB1/HSPA1L/ATXN3/CAMK2D/NUP93/ATR/CETN1/BAG2/ATP2A2/CHORDC1/NUP205/MAPK1/YWHAE/CASQ1/EIF2B1/NUP50/TGFB1I1/DNAJA1/CD34/EIF2B3/HSP90AB1/MICA/VCP/MTOR/TRPV4/BAG5/HSBP1L1/EIF2B2/ATXN3L/DAXX/ST8SIA1/TRPV3/POM121C/AAAS/TRPV2/CAMK2B	88
BP	GO:0002223	stimulatory C-type lectin receptor signaling pathway	60/7096	113/18670	0.0007637	0.00957	0.007135	FYN/ICAM2/BCL10/LYN/ICAM3/CLEC4D/PSMB9/CUL1/CLEC4E/PSMB8/PSMA5/PSMD11/PRKACB/NFKB1/KRAS/PSME1/RELA/PAK1/PSMB10/PSMA1/PSMA4/PRKCD/TAB3/TRAF6/IKBKG/CD209/HRAS/RELB/PSMB1/PAK2/PSMC4/PLCG2/PSMD13/MUC2/RAF1/PSMB3/PSMB5/PSMD6/MUC1/PSMC3/TAB1/PSME3/PSMC6/PRKACA/NRAS/MUC6/PSMC1/PSMD8/PSMA2/MUCL1/PSMC5/PSMC2/PSMB2/PSMD4/MALT1/CHUK/PSMD1/PSMB4/PSMD9/PSMD3	60
BP	GO:0046394	carboxylic acid biosynthetic process	209/7096	462/18670	0.0007742	0.009652	0.007196	IGF1/ALOX5/CBFA2T3/HK3/ATP2B4/PDK4/RBP1/ANXA1/GCH1/NANP/SEPHS2/VCAN/ALOX5AP/ABCC5/LDHA/FBP1/PGK1/STARD4/CYP27A1/CBR4/STAT3/PFKFB3/NUP62/NUP160/PFKM/PTGS2/PFKP/GAPDH/ADIPOR1/ADI1/MIF/PSPH/RDH10/OSBPL9/NUP214/MTR/ACOT7/SLC45A3/PER2/APOC1/MGST2/SLC2A6/ACSM5/P2RX7/MGLL/DEGS1/CD74/ELOVL5/SCP2/NUPR1/AKR1C3/NFKB1/LPGAT1/ALDH18A1/PGAM1/PKM/GALK1/EIF6/TPI1/DHRS9/ZBTB7A/TGFB1/OSBPL1A/NUP85/HIF1A/APIP/ABCD3/SCD/HPGD/SEH1L/MYO5A/OXSM/AKR1A1/NR1H2/ERLIN1/INSR/NAGS/ALDOC/NUP43/FADS3/ACLY/ENO1/MTRR/IDO1/DPYD/ENOPH1/ALDOA/IL1B/CSPG4/TECR/ERLIN2/POM121/SLC27A2/HSD17B4/ACACB/OGDH/GATM/SLC35D1/ACOX2/ASNSD1/ELOVL7/SIRT1/GPX4/GPI/GLUD1/PDGFB/PLOD1/PFKFB4/PPARGC1A/ABHD3/DECR2/CHST14/MLYCD/KYNU/APOA5/HAAO/PNPLA8/PTGES3/DHTKD1/MTAP/SLC25A12/ALOX15B/SHMT2/LDHC/GLUD2/PRKAG2/MYOG/NCOR1/CYP2D6/SERINC3/CYP1A2/PFKFB1/ATIC/SCAP/NUP88/HDAC4/ALDH8A1/CTH/ASNS/NR1H3/BHMT/PLOD2/NUP107/CH25H/GAMT/OSBPL2/HPGDS/FOXK2/ABCB11/DDIT4/ACADVL/BCAN/GSTM4/GLS/GOT2/PGK2/PFKFB2/ARNT/AP2A1/AGXT2/INSIG1/SHMT1/CEMIP/FABP5/BRCA1/DHFR/AASDHPPT/PPARA/NUP93/ADIPOR2/GGT7/PRKAA1/PSEN1/NUP205/MGST3/GGTA1P/GGT5/ENO2/SLC4A1/SRR/FPGS/CAD/NUP50/IFNG/PRKAG1/OGT/CHST12/BCAT2/ESRRB/ZBTB20/ADPGK/APP/ELOVL6/ABCD1/CRABP2/GGTLC1/PFKL/PLP1/CYP46A1/PHGDH/CYP2C8/NR1H4/FADS2/POM121C/AAAS/PTGS1/HSD17B12/ACOT8/PRKAB1	209
BP	GO:0009127	purine nucleoside monophosphate biosynthetic process	91/7096	183/18670	0.0007762	0.009652	0.007196	IGF1/CBFA2T3/HK3/LDHA/PINK1/FBP1/PGK1/VPS9D1/STAT3/PFKFB3/NUP62/NUP160/PFKM/PFKP/GAPDH/NUP214/SLC2A6/P2RX7/NUPR1/AK3/PGAM1/AK2/PKM/GALK1/EIF6/TPI1/ZBTB7A/TGFB1/GMPS/NUP85/HIF1A/SEH1L/ADK/INSR/ALDOC/PAICS/NUP43/IMPDH1/ENO1/DNAJC30/ALDOA/POM121/OGDH/GPI/PFKFB4/PPARGC1A/FLCN/DHTKD1/SLC25A12/LDHC/PRKAG2/MYOG/NCOR1/PFKFB1/ATIC/NUP88/HDAC4/NUP107/PPAT/FOXK2/DDIT4/AMPD2/PGK2/PFKFB2/ADA/ARNT/PPARA/NUP93/SLC25A13/PRKAA1/PSEN1/NUP205/ENO2/PID1/SLC4A1/TREM2/NUP50/IFNG/PRKAG1/OGT/ESRRB/ZBTB20/VCP/ADPGK/TAZ/APP/AMPD3/LHPP/PFKL/POM121C/AAAS	91
BP	GO:0009168	purine ribonucleoside monophosphate biosynthetic process	91/7096	183/18670	0.0007762	0.009652	0.007196	IGF1/CBFA2T3/HK3/LDHA/PINK1/FBP1/PGK1/VPS9D1/STAT3/PFKFB3/NUP62/NUP160/PFKM/PFKP/GAPDH/NUP214/SLC2A6/P2RX7/NUPR1/AK3/PGAM1/AK2/PKM/GALK1/EIF6/TPI1/ZBTB7A/TGFB1/GMPS/NUP85/HIF1A/SEH1L/ADK/INSR/ALDOC/PAICS/NUP43/IMPDH1/ENO1/DNAJC30/ALDOA/POM121/OGDH/GPI/PFKFB4/PPARGC1A/FLCN/DHTKD1/SLC25A12/LDHC/PRKAG2/MYOG/NCOR1/PFKFB1/ATIC/NUP88/HDAC4/NUP107/PPAT/FOXK2/DDIT4/AMPD2/PGK2/PFKFB2/ADA/ARNT/PPARA/NUP93/SLC25A13/PRKAA1/PSEN1/NUP205/ENO2/PID1/SLC4A1/TREM2/NUP50/IFNG/PRKAG1/OGT/ESRRB/ZBTB20/VCP/ADPGK/TAZ/APP/AMPD3/LHPP/PFKL/POM121C/AAAS	91
BP	GO:0043487	regulation of RNA stability	91/7096	183/18670	0.0007762	0.009652	0.007196	MYD88/ZFP36/SLC11A1/VIM/PSMB9/PSMB8/ZC3H14/NUP214/PSMA5/PSMD11/YTHDF3/MOV10/TNPO1/HNRNPR/METTL14/GIGYF2/PSME1/THRAP3/PAIP1/FASTKD1/PSMB10/HSPB1/PSMA1/PSMA4/PRKCD/METTL3/NAF1/SAMD4B/NPM1/PSMB1/PSMC4/DHX9/DCP2/PSMD13/ZC3H12D/PSMB3/PUM2/PSMB5/PSMD6/PSMC3/SCGB1A1/FTO/HNRNPC/PSME3/XRN1/MAPKAPK2/EXOSC2/PSMC6/HNRNPA0/RNASEL/CSDC2/UBC/EXOSC7/HNRNPD/CPEB3/YBX3/HNRNPM/TBRG4/FMR1/PSMC1/ZFP36L2/EIF4G1/DXO/PSMD8/PSMA2/EXOSC9/VIP/EXOSC3/PCID2/SET/PSMC5/PSMC2/PSMB2/PSMD4/MTOR/SAMD4A/EXOSC6/TIRAP/EXOSC8/PSMD1/ROCK2/PSMB4/SYNCRIP/BOLL/TARDBP/PRKCA/PSMD9/PSMD3/EXOSC5/PLEKHN1/UPF1	91
BP	GO:0050702	interleukin-1 beta secretion	32/7096	53/18670	0.0007832	0.009698	0.00723	NOD2/WNT5A/ARG2/LILRA5/NLRP3/TNFAIP3/LILRA2/NLRP12/P2RX7/GBP5/AIM2/TRIM16/CD36/PANX1/SERPINB1/TLR4/ABCA1/PML/HMGB1/CASP1/LGALS9/FZD5/CPTP/TLR8/APOA1/NLRP1/NLRP2/FOXP1/CCL19/CCR7/HMGB4/TLR6	32
BP	GO:0030656	regulation of vitamin metabolic process	11/7096	13/18670	0.0007904	0.009698	0.00723	VDR/RDH10/TNF/CD320/AKR1C3/NFKB1/IL1B/CLYBL/CYP27B1/SNAI1/IFNG	11
BP	GO:0035589	G protein-coupled purinergic nucleotide receptor signaling pathway	11/7096	13/18670	0.0007904	0.009698	0.00723	P2RY14/P2RY8/PTAFR/P2RY6/GPR171/P2RY12/GPR34/P2RY13/P2RY4/P2RY10/P2RY1	11
BP	GO:0035723	interleukin-15-mediated signaling pathway	11/7096	13/18670	0.0007904	0.009698	0.00723	IL2RG/STAT3/IL15/IL2RB/STAT5A/SHC1/IL15RA/GRB2/PLCB1/JAK1/CD4	11
BP	GO:0043301	negative regulation of leukocyte degranulation	11/7096	13/18670	0.0007904	0.009698	0.00723	CCR2/HMOX1/HLA-F/ABR/BCR/CD300A/LGALS9/RABGEF1/IL13RA2/CD84/FOXF1	11
BP	GO:0046349	amino sugar biosynthetic process	11/7096	13/18670	0.0007904	0.009698	0.00723	NANP/PGM3/GNPDA1/UAP1/NAGK/RENBP/GNPNAT1/UAP1L1/GFPT1/GNE/GFPT2	11
BP	GO:0071350	cellular response to interleukin-15	11/7096	13/18670	0.0007904	0.009698	0.00723	IL2RG/STAT3/IL15/IL2RB/STAT5A/SHC1/IL15RA/GRB2/PLCB1/JAK1/CD4	11
BP	GO:0006081	cellular aldehyde metabolic process	42/7096	74/18670	0.0007987	0.009745	0.007265	TALDO1/ALDH3A2/ALDH9A1/ALDH1A1/RDH10/ALDH7A1/ADH5/AKR1C3/AKR7A2/PGAM1/RELA/RPE/TPI1/TKT/CYP1B1/AKR7A3/ESD/PNKD/AKR1A1/RPIA/BMP2/AKR1C1/HAGH/IDH1/ALDH4A1/G6PD/IDH2/PGM2/BMP5/KHK/ALDH8A1/DERA/GOT2/AGXT2/PGD/BCO2/GRHPR/GLYCTK/ALDH3A1/CACNA1H/PGLS/RBKS	42
BP	GO:0032418	lysosome localization	42/7096	74/18670	0.0007987	0.009745	0.007265	RAC2/LYN/BLOC1S2/IL4R/HMOX1/C12orf4/PLEKHM2/STXBP1/LAT2/STXBP2/TFEB/FGR/FAM98A/LAMTOR1/VPS33A/RASGRP1/TMEM106B/PLEKHM1/S100A13/MYH9/PLA2G3/ADORA2B/PIK3CD/UNC13D/NDEL1/SYTL4/CD300A/LGALS9/FER/RABGEF1/BLOC1S1/IL13RA2/RAB3A/CD84/HPS6/KIF1B/NR4A3/PIK3CG/SNX4/FOXF1/LAT/ARL8B	42
BP	GO:1901991	negative regulation of mitotic cell cycle phase transition	119/7096	248/18670	0.0007993	0.009745	0.007265	KLF4/TPRA1/DUSP1/CDKN2D/CDKN1A/MAD2L2/GPNMB/PSMB9/CUL1/PSMB8/DYNC1LI1/ZNF655/RGCC/HUS1B/PSMA5/SLFN11/PSMD11/EZH2/SPDL1/PKD2/GIGYF2/PSME1/BTG2/GPR132/CDK4/TAOK3/ZNF830/PSMB10/PSMA1/PSMA4/SYF2/CDKN2B/PLK2/SFN/KLHL22/CDK5RAP2/PSMB1/PSMC4/DONSON/PML/PSMD13/CDK2AP2/PSMB3/CCND1/ZNF207/LCMT1/PSMB5/PSMD6/ATM/TNKS1BP1/BUB3/MUC1/PSMC3/CTDSPL/PLK3/PSME3/NACC2/RAD17/NDC80/BCL2/PCNA/BAX/PSMC6/CRADD/CASP2/CTDSP1/RFWD3/CDKN1B/CDKN2C/CNOT4/FHL1/PLAGL1/GEN1/ARID3A/ZW10/FOXO4/TICRR/BTN2A2/MIIP/E2F4/BRCA1/CNOT7/GML/CTDSP2/MDM2/PSMC1/ZFP36L2/CLSPN/WEE1/RBL2/DCUN1D3/PSMD8/PSMA2/FBXL7/TOPBP1/CDC20/PCID2/RB1/CNOT10/CARM1/JADE1/PSMC5/PSMC2/PSMB2/PSMD4/TRIAP1/AURKA/BRSK1/CDC73/RBX1/SOX4/IK/PSMD1/PRMT1/PSMB4/ZFYVE19/PSMD9/PSMD3/E2F8	119
BP	GO:0015931	nucleobase-containing compound transport	116/7096	241/18670	0.0008002	0.009745	0.007265	SLC29A1/SLC29A3/ZFP36/TSC1/NXF1/SRSF5/SLC25A19/NUP62/NUP160/SLC25A25/SLC33A1/CHTOP/NUP214/FLOT1/ENY2/G3BP2/AGFG1/P2RX7/KHDRBS1/RAN/ALYREF/RNPS1/EIF6/MX2/MAGOHB/SARNP/NUP85/NXT1/CETN3/SEH1L/SIDT1/YTHDC1/BICD2/NUP43/HNRNPA1/NPM1/HNRNPA2B1/PURA/RBM8A/MVP/SNUPN/FYTTD1/DDX19B/DHX9/U2AF1/POM121/SLC35B4/ZNF593/SRSF3/SYMPK/SLC35D1/XPOT/SFPQ/SLC28A3/CPSF3/SLC25A5/MYO1C/ATXN2/ARC/RBM27/TST/FIP1L1/NUP88/THOC2/SRSF6/SRSF7/CKAP5/NUP107/CDC40/SLC29A2/NPIPA1/THOC5/POLR2D/SLC35B1/SLC35A3/TOMM20/NXT2/U2AF1L4/SLC25A33/EIF5A/NUP93/CETN2/SLC35C1/LTV1/THOC6/RIOK2/SLC35A5/SSB/SRRM1/NUP205/FMR1/PHAX/SRSF4/EIF4E/NUP50/PARP11/DHX38/SLC25A24/MCM3AP/PCID2/HNRNPA3/CPSF2/SLC25A32/CPSF1/ABCD1/PNPT1/SIDT2/SLC35A2/GJA1/SLC35D2/RRS1/POM121C/AAAS/SLC29A4/UPF1/RFTN1	116
BP	GO:1903900	regulation of viral life cycle	76/7096	149/18670	0.0008061	0.009798	0.007305	TRIM32/FCN1/PLSCR1/OASL/LAMP3/IFITM2/TNF/IFITM1/CD74/TRIM13/VPS37B/IFITM3/CHMP4B/MORC2/ISG20/STAU1/PTX3/TRIM26/DDB1/ADARB1/OAS3/IFI27/RSAD2/CCL5/SRPK2/PML/ISG15/VAPB/TRIM11/APOBEC3G/MAVS/APOBEC3C/IFIT5/DDX3X/ILF3/BANF1/ZC3HAV1/TRIM21/TARBP2/BCL2/CCL8/TBC1D20/TNIP1/CHMP2A/INPP5K/CCNK/TSG101/MX1/TOP2B/LGALS1/SETDB1/RNASEL/LGALS9/IFIT1/SRPK1/VPS4B/EIF2AK2/CNOT7/PKN2/MID2/ANXA2P2/FMR1/FBXL2/SMC3/TRIM15/CD4/TRIM6/EIF2AK4/PC/ANXA2/ADAR/PPIB/NUCKS1/TOP2A/APCS/BTBD17	76
BP	GO:1903364	positive regulation of cellular protein catabolic process	72/7096	140/18670	0.0008109	0.009838	0.007334	CBFA2T3/EZR/TMTC3/SMAD7/TNFAIP3/KEAP1/DDRGK1/FBXW7/CTSC/RNF139/BCAP31/NUPR1/APOE/GSK3B/MAGEF1/RNF19B/FBXL5/EDEM1/RDX/SGTA/ZFAND2A/SOCS5/PTK2B/CSNK1D/PTTG1IP/RNF217/CEBPA/PLK2/ANKIB1/GCLC/PSMC4/UQCC2/LDLR/LRP1/CLU/EDEM2/LRRK2/SUMO1/PTK2/HSPBP1/CSNK1A1/CSNK1E/RNFT1/ARIH2/PLK3/DISC1/UBQLN2/TRIB2/BBS7/DET1/NKD2/KLHL40/STUB1/NFE2L2/ATXN3/CAV3/BAG2/DVL1/PSEN1/FMR1/MDM2/MSN/PSMC1/TREM2/RNF185/PSMC2/VCP/AURKA/RBX1/KCNE2/CHFR/MAPK9	72
BP	GO:0006101	citrate metabolic process	23/7096	35/18670	0.000817	0.009875	0.007362	MDH1/ACLY/ME3/OGDH/IDH1/ACO1/IDH2/DHTKD1/FH/MDH1B/PDHB/IREB2/SUCLG2/DLAT/IDH3A/PDHA2/FAHD1/SDHA/SDHD/ME2/IDH3G/SDHAF2/NNT	23
BP	GO:0060338	regulation of type I interferon-mediated signaling pathway	23/7096	35/18670	0.000817	0.009875	0.007362	PTPN6/IRF7/WNT5A/PTPN2/NLRC5/YTHDF3/CDC37/UBE2K/METTL3/CACTIN/SAMHD1/MMP12/MAVS/LSM14A/RNASEL/ZBP1/CNOT7/MUL1/FADD/HSP90AB1/IFNAR2/TRIM6/ADAR	23
BP	GO:0032757	positive regulation of interleukin-8 production	30/7096	49/18670	0.0008189	0.009879	0.007365	MYD88/NOD2/TLR1/TLR2/CLEC7A/BCL10/WNT5A/CD58/FCN1/CD2/TNF/CD74/FFAR2/TLR5/HYAL2/TLR4/DDX58/IL1B/MAVS/ZNF580/PRKD2/SERPINE1/LGALS9/F2R/FADD/TLR8/TLR3/LBP/TIRAP/CD244	30
BP	GO:0030100	regulation of endocytosis	133/7096	281/18670	0.0008221	0.009899	0.00738	FPR2/IL2RG/TLR2/DLL1/CLEC7A/APPL2/ARF6/ATG3/SLC11A1/WNT5A/CSK/AZU1/SOD1/SYT11/HCK/LYAR/CAMK1D/PACSIN2/ACTN4/FLOT1/APOC1/SCARB1/PTPRC/IL15/HFE/TNF/APOE/RAB31/LILRB1/TBC1D5/CD22/MIB1/AXL/TGFB1/PPP3CB/ARRB1/CD36/NR1H2/LRPAP1/CD63/HNRNPK/PTX3/ITSN1/FGR/IL2RB/ABR/USP46/VEGFA/EHD4/ABL1/OPHN1/IL1B/CD151/SIRPB1/NUMB/PLCG2/SDCBP/RAP1A/RAB20/CD300LF/SFRP4/LRP1/HMGB1/CLU/RAC1/SNX33/LRRK2/ATXN2/ARC/CBLL1/APOA5/BICD1/BCR/ARF1/DNAJC6/TOR1A/SPHK1/IL15RA/SH3GL1/DNM1/UBQLN2/DNM2/RAB5C/SERPINE1/CD47/TSG101/NR1H3/RAB5A/ITGA2/AP2S1/MTMR2/CD300A/CYBA/RABGEF1/CD2AP/DNM1L/AP2A1/CALR/ABCA7/ABL2/CAV3/ANXA2P2/FMR1/MKLN1/MERTK/APOA1/SIRPG/TREM2/IFNG/SYT4/ANKRD13D/ANXA2/PRTN3/SCAMP5/TSPAN1/PICK1/SNCA/CLIP3/CCL19/GSG1L/TULP1/PICALM/APPL1/ATAD1/GREM1/ARFGAP1/RAB27A/BIN1/PACSIN3/SNX17/PIK3CB/PTPRJ/APLN	133
BP	GO:1903580	positive regulation of ATP metabolic process	29/7096	47/18670	0.0008328	0.01001	0.007462	IGF1/PINK1/PGK1/STAT3/PFKFB3/P2RX7/NUPR1/HIF1A/ISCU/INSR/ENO1/PFKFB4/PPARGC1A/SLC25A12/MYOG/PFKFB1/PGK2/PFKFB2/ARNT/PRKAA1/PSEN1/PID1/TREM2/IFNG/ESRRB/ZBTB20/VCP/TAZ/APP	29
BP	GO:1901988	negative regulation of cell cycle phase transition	127/7096	267/18670	0.0008382	0.01006	0.007497	KLF4/TPRA1/DUSP1/CDKN2D/CDKN1A/MAD2L2/GPNMB/PSMB9/CUL1/PSMB8/DYNC1LI1/ZNF655/RGCC/HUS1B/ATF5/PSMA5/SLFN11/PSMD11/EZH2/SPDL1/PKD2/GIGYF2/PSME1/BTG2/GPR132/CDK4/TAOK3/ZNF830/PSMB10/PSMA1/PSMA4/UIMC1/SYF2/CDKN2B/PLK2/SFN/KLHL22/CDK5RAP2/PSMB1/PSMC4/DONSON/PML/PSMD13/CDK2AP2/PSMB3/CCND1/ZNF207/LCMT1/PSMB5/PSMD6/ATM/TNKS1BP1/BUB3/MUC1/PSMC3/CTDSPL/PLK3/PSME3/NACC2/RAD17/NDC80/BCL2/PCNA/BAX/PSMC6/CRADD/CASP2/CTDSP1/RFWD3/CDKN1B/CDKN2C/CNOT4/FHL1/PLAGL1/GEN1/ARID3A/ZW10/FOXO4/TICRR/BTN2A2/MIIP/DTL/MOS/E2F4/BRCA1/CNOT7/GML/CTDSP2/MDM2/PSMC1/ZFP36L2/CLSPN/WEE1/RBL2/DCUN1D3/PSMD8/PSMA2/FBXL7/TOPBP1/CDC20/PCID2/RB1/C10orf99/MEN1/CNOT10/CARM1/JADE1/PSMC5/PSMC2/PSMB2/PSMD4/TRIAP1/AURKA/BRSK1/CDC73/RBX1/SOX4/BRCC3/IK/PSMD1/PRMT1/PSMB4/ZFYVE19/PSMD9/PSMD3/E2F8/SUSD2	127
BP	GO:0010001	glial cell differentiation	106/7096	218/18670	0.000844	0.01011	0.007534	S100A8/FPR2/TLR2/MPP5/DLL1/GRN/LYN/SKI/CSK/SOD1/STAT3/VIM/DUSP10/MAP2K1/LAMB2/SLC45A3/GSTP1/TNF/TNFRSF21/METTL14/KRAS/MIR142/RELA/TGFB1/LAMC3/ROR2/METTL3/NRG1/MBD1/B4GALT6/TLR4/EIF2B5/BMP2/DTX1/CDK5/ABL1/NAB1/IL1B/S100B/AGER/HDAC11/LDLR/LRP1/CLU/IL6ST/NDRG1/ZNF488/TTBK1/EGR2/IL6/TAL1/BACE2/DICER1/HDAC10/HDAC2/ID2/CDKN2C/CLCF1/ROR1/SPINT1/ADAM22/SH3TC2/LGI4/DAB1/B4GALT5/PRMT5/LPAR1/HES1/CNTF/NFE2L1/IFNGR1/EGFR/MXRA8/LAMA2/PSEN1/MAPK1/DNER/ERCC2/TREM2/EIF2B1/IFNG/EIF2B3/CNP/PRPF19/OLIG1/NR2E1/RELN/MTOR/RHOA/PICK1/APP/DAG1/SOX4/TSPAN2/PTPRZ1/SLC8A3/EIF2B2/PLP1/PHGDH/SMO/KLF15/DAAM2/ERBB3/BIN1/NTRK2/POU3F1	106
BP	GO:0072350	tricarboxylic acid metabolic process	25/7096	39/18670	0.0008463	0.01011	0.007538	MDH1/SIRT4/ACLY/ME3/OGDH/IDH1/ACO1/GLUD1/IDH2/DHTKD1/FH/MDH1B/PDHB/IREB2/SUCLG2/DLAT/IDH3A/PDHA2/FAHD1/SDHA/SDHD/ME2/IDH3G/SDHAF2/NNT	25
BP	GO:0042129	regulation of T cell proliferation	79/7096	156/18670	0.0008477	0.01011	0.007538	IGF1/PNP/CCR2/RAC2/PTPN6/LILRB2/ANXA1/CD55/IRF1/ARG2/GPNMB/TNFRSF14/SH3RF1/CEBPB/PTPRC/IL15/TNFRSF21/LILRB1/TGFB1/CCDC88B/LEP/TNFSF13B/CORO1A/TRAF6/CLC/IL20RB/ZBTB7B/HLA-DPB1/HLA-DPA1/HLA-E/NCK1/CD209/CASP3/IDO1/IL1B/AIF1/AGER/CCL5/RASAL3/HLA-DMB/ICOSLG/HMGB1/EFNB1/IGFBP2/IL6ST/HLA-G/IL6/CTLA4/GLMN/VSIG4/SCGB1A1/PDCD1LG2/BMP4/CD1D/IL12RB1/CD274/LGALS9/EBI3/BTN2A2/HES1/IL18/FADD/CD276/TFRC/TNFSF4/HAVCR2/SPTA1/TNFSF18/CD4/TNFRSF13C/IL12B/CD80/PRKCQ/CCL19/TNFSF8/CD3E/TWSG1/CD24/IL23A	79
BP	GO:0035690	cellular response to drug	170/7096	369/18670	0.0008501	0.01011	0.007538	CRHBP/KLF4/NQO1/SLC8A1/CD69/NOD2/KLF2/FYN/KCNMB1/ATP2B4/ANXA1/SPI1/ATG7/PINK1/FBP1/GCLM/AIFM1/SOD1/SRD5A1/RAP1B/STAT6/VIM/PTGS2/GNB1/PLEKHA1/TNFAIP3/GNA15/MTR/MYC/FOLR2/RNF149/PSAP/P2RX7/EGR1/TNF/EZH2/HMOX1/NFKB1/AIM2/ATF4/RELA/AXL/ACTB/CDK4/TGFB1/PPP3CB/SIN3A/CYP1B1/HGF/PTAFR/CTNNA1/MAP1LC3A/GNAQ/PCK2/MAPK7/BCL11A/PCGF2/PRKCD/ADAM15/MAPK13/BAIAP2/PPP1R14A/TFAP4/RYR1/PTPN22/NET1/HSPA5/HNRNPA1/PDE4B/ABL1/GCLC/IL1B/AIF1/ARHGEF2/RAP1A/AHR/QDPR/P2RY12/CRK/CCL7/PPM1F/SIRT1/TRPM4/KLF9/TRPM2/OSER1/ADCY7/IL6/PDGFB/LRRK2/SMYD3/PPARGC1A/ADCY1/ETS1/MIR34A/SETX/DCPS/SPHK1/HDAC2/ZNF580/XRN1/ADCY3/DNM2/GNAI2/PCNA/NME1/MMP3/MAP4K1/PPAT/KCNQ1/CYBA/CYBB/TIMELESS/HNRNPD/DDIT4/MAP3K5/KDM6B/CHRM2/FDX1/CHRNA4/NFE2L2/IMPACT/PLCB1/BRCA1/EGFR/TXN/AMIGO1/TRAF2/DNMT3A/HSP90B1/TFRC/SLIT2/PRKAA1/FMR1/MDM2/MAPK1/CHRNB2/P2RY4/BAD/CASQ2/CAD/EIF4E/NR4A3/TMEM38B/HSP90AB1/CCNA2/TLR3/REN/WDR35/MSX1/IL18RAP/PDE8A/PDCD10/CIB2/SIGMAR1/MET/SSH1/KCNE2/ROCK2/EFTUD2/ENDOG/DAXX/SPIDR/SLAMF8/GNA11/P2RY1/PDGFD/FOXO3/MEF2C/ZNF277	170
BP	GO:0030890	positive regulation of B cell proliferation	26/7096	41/18670	0.0008507	0.01011	0.007538	CDKN1A/BST1/BCL6/CD40/MIF/PTPRC/CD74/CD320/TICAM1/TNFSF13B/TLR4/SLC39A10/IL7/IRS2/BCL2/NFATC2/CLCF1/ADA/TFRC/CHRNB2/TNFRSF4/TNFRSF13C/GPR183/TIRAP/ATAD5/MEF2C	26
BP	GO:0071236	cellular response to antibiotic	75/7096	147/18670	0.0008606	0.01013	0.007554	CRIP1/KLF4/NQO1/KLF2/KCNMB1/ANXA1/SPI1/PINK1/AIFM1/STAT6/PLEKHA1/TNFAIP3/PSAP/EGR1/EZH2/SLC9A1/ACTR2/RELA/AXL/CYP1B1/HGF/MAP1LC3A/MAPK7/PCGF2/PRKCD/MAPK13/NET1/HSPA5/HNRNPA1/ABL1/AHR/CLU/CCL7/SIRT1/TRPM2/OSER1/ADCY7/IL6/PDGFB/LRRK2/ADCY1/ETS1/MIR34A/SETX/SPHK1/HDAC2/ZNF580/XRN1/ADCY3/PCNA/CDKN1B/CYBB/TIMELESS/MAP3K5/KDM6B/FDX1/NFE2L2/IMPACT/TXN/DNMT3A/PRKAA1/MDM2/NR4A3/ATP7A/IL18RAP/PDE8A/PDCD10/SIGMAR1/MET/ENDOG/DAXX/PDGFD/FOXO3/MEF2C/ZNF277	75
BP	GO:0090263	positive regulation of canonical Wnt signaling pathway	75/7096	147/18670	0.0008606	0.01013	0.007554	RBPJ/PSMB9/JRK/ZBED3/PSMB8/WLS/CSNK1G2/LGR4/PSMA5/PSMD11/GPRC5B/NFKB1/PSME1/PSMB10/PSMA1/PSMA4/CSNK1D/ROR2/RUVBL1/FZD9/PSMB1/GID8/PSMC4/UBR5/FRAT1/RNF146/SFRP4/PSMD13/PSMB3/TRPM4/LRRK2/ASPM/SULF2/DDX3X/PSMB5/PSMD6/EDA/CSNK1E/PSMC3/NRARP/PSME3/PSMC6/KANK1/CSNK1G3/ZBED2/GSKIP/SEMA5A/DKK2/EGFR/LGR5/PSMC1/PSMD8/PSMA2/ARNTL/PIN1/TBL1X/PSMC5/LGR6/PSMC2/PSMB2/PSMD4/VCP/PRDM15/CDH3/SOX4/XIAP/PSMD1/UBE2B/WNT10B/PSMB4/CSNK1G1/DAAM2/PSMD9/PSMD3/WNK2	75
BP	GO:0002827	positive regulation of T-helper 1 type immune response	15/7096	20/18670	0.0008606	0.01013	0.007554	CCR2/IL27RA/ANXA1/SLC11A1/IL18R1/SOCS5/IL1B/IL1R1/IL12RB1/HLX/IL18/IL12B/CD80/CCL19/IL23A	15
BP	GO:0009219	pyrimidine deoxyribonucleotide metabolic process	15/7096	20/18670	0.0008606	0.01013	0.007554	NEIL2/UNG/NT5C/CDADC1/CMPK2/TDG/TYMS/SHMT1/TBPL1/DCTD/DCTPP1/NT5M/DUT/MBD4/SMUG1	15
BP	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process	15/7096	20/18670	0.0008606	0.01013	0.007554	CCR2/TLR1/CLEC7A/AZU1/JAK2/HSPB1/TLR4/AGER/TYROBP/MAPKAPK2/CYBB/PSEN1/IFNG/LBP/APP	15
BP	GO:0009119	ribonucleoside metabolic process	53/7096	98/18670	0.0008635	0.01013	0.007554	PNP/UPP1/GNAI3/ACPP/AHCY/RAN/AK3/NFS1/MPP1/HDDC3/GMPS/DGUOK/RAB23/APIP/ADK/MBIP/CDADC1/GUK1/IMPDH1/CTPS2/MTRR/ENOPH1/CMPK1/MOCS2/APOBEC3G/PRTFDC1/LRRK2/APOBEC3C/NME3/MTAP/APOBEC2/NME4/GTPBP1/GMPR2/RHOQ/NME1/GAMT/MOCS3/ADA/AHCYL2/AHCYL1/UCK1/APOBEC3B/CTPS1/CAD/CDA/RHOA/UCKL1/ENPP4/UPP2/AMPD3/ADAL/GIMAP7	53
BP	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	53/7096	98/18670	0.0008635	0.01013	0.007554	TRIM32/CDKN2D/PINK1/TMBIM6/PTGS2/BCL2A1/MIF/ACKR3/CD44/CD74/CXCL12/HIF1A/WFS1/HSPB1/MAPK7/PTTG1IP/TMEM161A/NDUFS3/MCL1/HTRA2/ENO1/ARHGEF2/CLU/SIRT1/ELL3/LRRK2/PLAUR/DDX3X/MUC1/VNN1/TXNDC12/IVNS1ABP/MMP9/BCL2/NOC2L/CREB3/PDX1/VDAC2/YBX3/NFE2L2/RRM2B/MDM2/TAF9B/SNAI1/DNAJA1/HYOU1/GPX1/TRIAP1/BAG5/BCL2L2/ATAD5/FIGNL1/DDIAS	53
BP	GO:0034121	regulation of toll-like receptor signaling pathway	40/7096	70/18670	0.0008792	0.0103	0.007678	TLR1/TLR2/APPL2/LYN/IRF7/IRF1/GRAMD4/TNFAIP3/BIRC2/LY96/FLOT1/LGR4/LILRA2/IRAK3/TICAM1/CD36/TLR5/TLR4/PTPN22/CACTIN/RSAD2/CD300LF/HMGB1/MFHAS1/TREML4/OTUD4/BIRC3/NR1H3/CD300A/WDFY1/CYBA/RAB7B/TLR3/LBP/TYRO3/RTN4/TIRAP/APPL1/TLR6/MIR146A	40
BP	GO:0001101	response to acid chemical	159/7096	343/18670	0.0008817	0.01031	0.007686	KLF4/NQO1/PKD2L1/KLF2/FYN/KCNMB1/TLR2/PTGER4/ATP2B4/PDK4/DUSP1/CDKN2D/ATG7/LYN/PINK1/GCLM/AIFM1/WNT5A/AKR1B1/PTGER2/TMBIM6/CAPN2/ADNP2/PTGS2/LRP11/GNB1/HMGCL/FOLR2/CEBPB/GDAP1/GSTP1/EGR1/TNF/AKR1C3/TESC/PKD2/IGFBP7/RELA/TRIM16/SH3BP4/CDK4/TWF2/AACS/ALAD/FIS1/PTAFR/FFAR2/SCD/CD36/PTK2B/LEP/BCL11A/P2RY6/BAIAP2/TMEM161A/HTRA2/PDGFC/AKR1C1/VEGFA/CAT/CASP3/KLHL22/IGF2R/GCLC/ABCA1/LAMTOR1/XRCC5/PTK6/LDLR/RRAGD/CREB1/IGFBP2/DGAT2/FABP3/PDGFB/GNG2/PPARGC1A/SLC10A3/SPARC/ATM/SETX/CRLS1/SHMT2/SCGB1A1/HDAC2/GDAP2/AKAP8/MYOG/RXRA/LAMTOR4/PCNA/CYP26B1/ASNS/CDKN1B/YY1/NME1/CPEB1/CFL1/ITGA2/GSS/CPT1A/TYMS/ABCB4/PDX1/CYBA/CYBB/HNRNPD/CPEB3/TEAD2/KRT8/RRAGA/UCP1/TOMM20/LAMTOR5/NSMF/SHMT1/DHFR/EGFR/AMIGO1/ABL2/SESN1/DNMT3A/AQP3/FZD4/TNFSF4/GIPR/PRKAA1/HAMP/PID1/P2RY4/UBR1/SOCS1/BAD/GNPAT/ATP7A/RET/GPRC6A/FZD7/CYP26A1/MMP2/COL18A1/MTOR/RHOA/WNT6/CCL19/CHUK/MGMT/CCR7/WNT10B/GJA1/LANCL2/NR1H4/SESN2/RBP4/PTCH1/SLC38A9/PDGFD/FZD10/NTRK2	159
BP	GO:0016053	organic acid biosynthetic process	209/7096	463/18670	0.0008861	0.01034	0.00771	IGF1/ALOX5/CBFA2T3/HK3/ATP2B4/PDK4/RBP1/ANXA1/GCH1/NANP/SEPHS2/VCAN/ALOX5AP/ABCC5/LDHA/FBP1/PGK1/STARD4/CYP27A1/CBR4/STAT3/PFKFB3/NUP62/NUP160/PFKM/PTGS2/PFKP/GAPDH/ADIPOR1/ADI1/MIF/PSPH/RDH10/OSBPL9/NUP214/MTR/ACOT7/SLC45A3/PER2/APOC1/MGST2/SLC2A6/ACSM5/P2RX7/MGLL/DEGS1/CD74/ELOVL5/SCP2/NUPR1/AKR1C3/NFKB1/LPGAT1/ALDH18A1/PGAM1/PKM/GALK1/EIF6/TPI1/DHRS9/ZBTB7A/TGFB1/OSBPL1A/NUP85/HIF1A/APIP/ABCD3/SCD/HPGD/SEH1L/MYO5A/OXSM/AKR1A1/NR1H2/ERLIN1/INSR/NAGS/ALDOC/NUP43/FADS3/ACLY/ENO1/MTRR/IDO1/DPYD/ENOPH1/ALDOA/IL1B/CSPG4/TECR/ERLIN2/POM121/SLC27A2/HSD17B4/ACACB/OGDH/GATM/SLC35D1/ACOX2/ASNSD1/ELOVL7/SIRT1/GPX4/GPI/GLUD1/PDGFB/PLOD1/PFKFB4/PPARGC1A/ABHD3/DECR2/CHST14/MLYCD/KYNU/APOA5/HAAO/PNPLA8/PTGES3/DHTKD1/MTAP/SLC25A12/ALOX15B/SHMT2/LDHC/GLUD2/PRKAG2/MYOG/NCOR1/CYP2D6/SERINC3/CYP1A2/PFKFB1/ATIC/SCAP/NUP88/HDAC4/ALDH8A1/CTH/ASNS/NR1H3/BHMT/PLOD2/NUP107/CH25H/GAMT/OSBPL2/HPGDS/FOXK2/ABCB11/DDIT4/ACADVL/BCAN/GSTM4/GLS/GOT2/PGK2/PFKFB2/ARNT/AP2A1/AGXT2/INSIG1/SHMT1/CEMIP/FABP5/BRCA1/DHFR/AASDHPPT/PPARA/NUP93/ADIPOR2/GGT7/PRKAA1/PSEN1/NUP205/MGST3/GGTA1P/GGT5/ENO2/SLC4A1/SRR/FPGS/CAD/NUP50/IFNG/PRKAG1/OGT/CHST12/BCAT2/ESRRB/ZBTB20/ADPGK/APP/ELOVL6/ABCD1/CRABP2/GGTLC1/PFKL/PLP1/CYP46A1/PHGDH/CYP2C8/NR1H4/FADS2/POM121C/AAAS/PTGS1/HSD17B12/ACOT8/PRKAB1	209
BP	GO:0008154	actin polymerization or depolymerization	102/7096	209/18670	0.0008923	0.01039	0.007749	MYADM/CDC42EP4/VASP/ARF6/DIAPH1/HCK/RHOBTB1/PLEKHG2/PSTPIP1/JAK2/TMSB10/SPIRE1/IQGAP2/ACTR2/CXCL12/MICAL1/TMOD3/LIMA1/HCLS1/GAS7/EVL/TWF2/RDX/PFN1/CDC42EP2/PTK2B/CFL2/CAPZA2/SWAP70/PRKCD/LATS1/GMFG/CORO1A/BAIAP2/ARFGEF1/CAPG/MICAL2/CAP1/NCK1/PSTPIP2/FCHSD1/AIF1/ARPC1A/CAPZA1/MKKS/SH3BP1/RAC1/ARPIN/SPTBN1/ARPC1B/CDC42EP3/CYFIP1/MYO1C/CORO1B/ARHGAP6/BBS4/ARF1/ARPC5L/COTL1/AVIL/MICALL2/CFL1/KANK1/TRIOBP/ARHGAP18/ADD3/TTC17/GRB2/PLEK/JMY/ACTR3B/FER/SEMA5A/DMTN/ACTR3/MSRB1/LMOD3/SCIN/PREX1/SLIT2/CCL26/ARPC4/SPTA1/SPTBN2/ENAH/WIPF1/ARPC2/KANK3/MTOR/CAP2/RHOA/PICK1/SNX9/CCR7/WAS/RHOBTB2/CCL24/BIN1/NCKAP1/FCHSD2/GHRL/FMN1	102
BP	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	174/7096	379/18670	0.0009075	0.01053	0.007854	CELF6/TRA2B/PCF11/NSRP1/JMJD6/SRSF5/PRPF4/DDX20/PRPF38A/U2SURP/KHDRBS1/CSTF3/HNRNPR/METTL14/HNRNPH1/ALYREF/PPIL1/DAZAP1/RNPS1/THRAP3/HNRNPH3/RBM7/MAGOHB/ZBTB7A/PCBP1/RBM42/SRSF10/CWF19L2/LSM5/CRNKL1/WDR83/METTL3/HNRNPK/MBNL1/YTHDC1/RBM4/RBM4B/COIL/SYF2/SNRNP25/SNRNP200/CWF19L1/HNRNPA1/CACTIN/HNRNPA2B1/RBM8A/SNUPN/SNRPB/GEMIN6/TXNL4A/DHX9/U2AF1/GTF2F2/SRPK2/LUC7L/SFSWAP/SRSF3/GEMIN7/SNRPA1/RNF113A/BCAS2/POLR2L/SYMPK/BUD31/SFPQ/HNRNPUL1/DHX8/CPSF3/RBM41/PDCD7/MBNL3/CLP1/CD2BP2/POLR2H/RBMXL1/PAPOLA/LSM7/SNIP1/RBM3/SNRPD1/PRPF3/USP4/SETX/SNRPA/PUF60/SNRPC/DCPS/ZCCHC8/MFAP1/ISY1/RSRC1/CWC22/SNRPB2/HNRNPC/FIP1L1/STRAP/PRPF40B/PRPF40A/FUS/HNRNPA0/LUC7L2/SRSF6/PRDX6/SREK1/SNRPF/SRSF7/DDX1/DDX46/RALY/CDC40/PRPF8/PCBP2/SF3A3/GTF2F1/CWC25/SMNDC1/SF3B4/CSTF1/SRPK1/HNRNPD/POLR2F/WEE2-AS1/PRMT5/AAR2/HNRNPM/POLR2D/TGS1/PRPF31/RBMXL2/C1QBP/U2AF1L4/RBMX2/SART1/SRRM1/POLR2K/FMR1/LOC100128988/CELF2/WDR77/USP49/UBL5/SRSF4/WBP11/ZC3H10/RBM25/CLNS1A/DHX38/HNRNPA3/SUGP1/GPKOW/CPSF2/PRPF19/CELF3/HMX2/SRRM4/PRPF39/SAP18/CPSF1/SNRPN/ZCRB1/AQR/CPSF7/PPWD1/IK/CHERP/SRRT/DHX16/EFTUD2/POLR2I/LUC7L3/SYNCRIP/SNRPG/SON/SNRPD2	174
BP	GO:0000398	mRNA splicing, via spliceosome	174/7096	379/18670	0.0009075	0.01053	0.007854	CELF6/TRA2B/PCF11/NSRP1/JMJD6/SRSF5/PRPF4/DDX20/PRPF38A/U2SURP/KHDRBS1/CSTF3/HNRNPR/METTL14/HNRNPH1/ALYREF/PPIL1/DAZAP1/RNPS1/THRAP3/HNRNPH3/RBM7/MAGOHB/ZBTB7A/PCBP1/RBM42/SRSF10/CWF19L2/LSM5/CRNKL1/WDR83/METTL3/HNRNPK/MBNL1/YTHDC1/RBM4/RBM4B/COIL/SYF2/SNRNP25/SNRNP200/CWF19L1/HNRNPA1/CACTIN/HNRNPA2B1/RBM8A/SNUPN/SNRPB/GEMIN6/TXNL4A/DHX9/U2AF1/GTF2F2/SRPK2/LUC7L/SFSWAP/SRSF3/GEMIN7/SNRPA1/RNF113A/BCAS2/POLR2L/SYMPK/BUD31/SFPQ/HNRNPUL1/DHX8/CPSF3/RBM41/PDCD7/MBNL3/CLP1/CD2BP2/POLR2H/RBMXL1/PAPOLA/LSM7/SNIP1/RBM3/SNRPD1/PRPF3/USP4/SETX/SNRPA/PUF60/SNRPC/DCPS/ZCCHC8/MFAP1/ISY1/RSRC1/CWC22/SNRPB2/HNRNPC/FIP1L1/STRAP/PRPF40B/PRPF40A/FUS/HNRNPA0/LUC7L2/SRSF6/PRDX6/SREK1/SNRPF/SRSF7/DDX1/DDX46/RALY/CDC40/PRPF8/PCBP2/SF3A3/GTF2F1/CWC25/SMNDC1/SF3B4/CSTF1/SRPK1/HNRNPD/POLR2F/WEE2-AS1/PRMT5/AAR2/HNRNPM/POLR2D/TGS1/PRPF31/RBMXL2/C1QBP/U2AF1L4/RBMX2/SART1/SRRM1/POLR2K/FMR1/LOC100128988/CELF2/WDR77/USP49/UBL5/SRSF4/WBP11/ZC3H10/RBM25/CLNS1A/DHX38/HNRNPA3/SUGP1/GPKOW/CPSF2/PRPF19/CELF3/HMX2/SRRM4/PRPF39/SAP18/CPSF1/SNRPN/ZCRB1/AQR/CPSF7/PPWD1/IK/CHERP/SRRT/DHX16/EFTUD2/POLR2I/LUC7L3/SYNCRIP/SNRPG/SON/SNRPD2	174
BP	GO:0033108	mitochondrial respiratory chain complex assembly	52/7096	96/18670	0.0009166	0.01062	0.007918	SCO2/NDUFA8/COA5/NDUFC1/UQCC1/NDUFB11/COX19/NDUFAF4/NDUFAF7/NDUFS3/COX20/NDUFA3/UQCC2/NDUFA11/TIMM21/UQCR10/NUBPL/SDHAF1/IMMP2L/NDUFA1/NDUFAF3/COX16/OXA1L/LYRM7/NDUFA10/NDUFB1/PET100/NDUFB5/NDUFS1/COA3/COA4/SLC25A33/NDUFB8/SURF1/COX14/NDUFB6/TIMMDC1/NDUFB3/NDUFS7/NDUFAF2/NDUFV2/ND4/TAZ/UQCRB/NDUFB2/SDHAF2/ECSIT/NDUFS2/AARS2/SMIM20/NDUFA7/TMEM126B	52
BP	GO:0009201	ribonucleoside triphosphate biosynthetic process	88/7096	177/18670	0.0009448	0.01093	0.008147	IGF1/CBFA2T3/HK3/LDHA/PINK1/FBP1/PGK1/VPS9D1/STAT3/PFKFB3/NUP62/NUP160/PFKM/PFKP/GAPDH/NUP214/SLC2A6/P2RX7/NUPR1/PGAM1/PKM/GALK1/EIF6/TPI1/ZBTB7A/TGFB1/NUP85/HIF1A/SEH1L/INSR/ALDOC/NUP43/IMPDH1/CTPS2/ENO1/DNAJC30/ALDOA/POM121/OGDH/GPI/PFKFB4/PPARGC1A/FLCN/DHTKD1/NME3/SLC25A12/LDHC/NME4/PRKAG2/MYOG/NCOR1/PFKFB1/NUP88/HDAC4/NME1/NUP107/FOXK2/DDIT4/PGK2/PFKFB2/ARNT/UCK1/PPARA/NUP93/SLC25A13/PRKAA1/PSEN1/NUP205/ENO2/PID1/SLC4A1/TREM2/CTPS1/CAD/NUP50/IFNG/PRKAG1/OGT/ESRRB/ZBTB20/VCP/ADPGK/UCKL1/TAZ/APP/PFKL/POM121C/AAAS	88
BP	GO:2001020	regulation of response to DNA damage stimulus	104/7096	214/18670	0.0009606	0.01109	0.008268	TRIM32/USP51/CDKN2D/SKIL/MAD2L2/PARP9/EID3/RAD51AP1/PMAIP1/EYA3/MIF/CEBPG/RNASEH2B/ACKR3/CD44/MYC/UBE2N/SPIRE1/KLHL15/CD74/ERCC6/ERCC4/MAGEF1/ACTR2/CXCL12/PPP4C/PPP4R2/IER3/EEF1E1/FEM1B/PRKCD/PTTG1IP/HNRNPK/ETAA1/UIMC1/TMEM161A/MCL1/DEK/RMI2/SETMAR/ABL1/WRNIP1/PARG/UBR5/DHX9/PML/HMGB1/SMCHD1/NUDT16L1/CLU/SIRT1/ELL3/CDK9/ATM/POLH/DTX3L/MUC1/HDAC10/RAD52/NACC2/BCL2/PCNA/XRCC1/PARP3/ERCC1/FUS/RFWD3/USP1/TIMELESS/ZMPSTE24/THOC5/KDM4D/FBXO4/SPRED1/DYRK3/BRCA1/EGFR/ATR/FMR1/MDM2/RTEL1/EYA4/ANKLE1/TAF9B/SNAI1/BCLAF1/RAD9A/TEX15/MSX1/TRIAP1/BRCC3/WDR76/AUNIP/NEK4/MGMT/WAS/PAXIP1/NUDT16/ATAD5/SPIDR/HIC1/FIGNL1/DDIAS/ERCC8	104
BP	GO:0006687	glycosphingolipid metabolic process	38/7096	66/18670	0.0009638	0.01111	0.008281	ASAH1/HEXB/CTSA/GM2A/ESYT2/SUMF1/PSAP/HEXA/SUMF2/GALC/PRKCD/B4GALT6/CLN3/GLA/ALDH5A1/CREM/ENPP7/BAX/B4GALNT1/NAGA/CLN6/B4GALT5/UGCG/ST8SIA4/CPTP/STS/ARSA/ST6GALNAC5/PRKAA1/CERK/NEU1/ST6GALNAC3/SMPD1/ST6GALNAC6/SMPD2/ST8SIA1/ST3GAL5/GLTP	38
BP	GO:0046777	protein autophosphorylation	113/7096	235/18670	0.0009695	0.01115	0.008315	FYN/STK17B/LYN/PINK1/OXSR1/CSK/GPNMB/FLT1/PIM1/HCK/CHP1/ULK2/CSNK1G2/SIK1/NLRP12/JAK2/PTPRC/ALK/IRAK3/VRK2/GSK3B/GRK5/MAPKAPK3/PEAK1/TAOK3/PAK1/PIM3/PTK2B/INSR/RAP2C/DYRK1B/FLT3/PDGFC/FGR/IGF1R/VEGFA/CDK5/ABL1/PAK2/RAP2B/MVP/NLK/TOM1L1/PTK6/MAP3K12/SIK2/DAPK1/SLK/EIF2S1/ITK/LCK/ACVR1B/PDGFB/LRRK2/EPHA8/PPP2R5C/PTK2/BCR/ATM/TNKS1BP1/MAPKAPK5/MARK3/MAK/TRIM24/GFRA2/PRKD2/MAPKAPK2/MARK2/PRKACA/TEC/MAP4K1/MAP2K2/MAP3K11/PDGFA/FER/FRK/CAMK2A/MOS/IMPACT/CAMK2D/EIF2AK2/ULK1/EGFR/ATR/ABL2/RIOK2/VRK1/EIF2AK1/MKNK2/MAP3K13/CAD/EPHB1/LMTK2/TXK/PPP2R5B/EIF2AK4/CSF1R/MTOR/CLK1/AURKA/TYRO3/PIM2/ERN1/DAPK2/MOB1B/ENG/STK16/GREM1/PDGFD/NTRK2/WNK2/CAMK2B/MAP3K9	113
BP	GO:1901216	positive regulation of neuron death	51/7096	94/18670	0.0009727	0.01117	0.008328	NQO1/ITGAM/FOS/FYN/GRN/AIFM1/WNT5A/CAPN2/FBXW7/EGR1/TNF/NUPR1/GSK3B/ATF4/ZNF746/FIS1/MCL1/TLR4/CDK5/CASP3/ABL1/CTSZ/CASP8/SRPK2/CLU/TYROBP/EIF2S1/ATM/BCL2L11/AIMP2/BAX/HDAC4/CASP2/MAP3K11/PITX3/DDIT4/MAP3K5/UBE2M/MAP2K4/BAD/IFNG/PPP1R13B/PIN1/MTOR/RHOA/SNCA/SSH1/PICALM/DAXX/TLR6/FOXO3	51
BP	GO:0046677	response to antibiotic	152/7096	327/18670	0.0009782	0.01118	0.008337	CRIP1/CRHBP/KLF4/NQO1/SLC8A1/S100A8/KLF2/FYN/KCNMB1/DUSP1/ANXA1/SPI1/LDHA/PINK1/TXNIP/AIFM1/SOD1/SRD5A1/STAT6/STAT3/CAPN2/PLEKHA1/TNFAIP3/BIRC2/RGS2/STAT1/CYB5R4/JAK2/GSTP1/PSAP/EGR1/EZH2/HMOX1/SLC9A1/HMGCR/ACTR2/RELA/AXL/UBE3A/AACS/ALAD/CYP1B1/HGF/MAP1LC3A/HPGD/PTK2B/MAPK7/LEP/PCGF2/PRKCD/HBB/MAPK13/HYAL2/KPNA4/KAT7/NET1/HSPA5/ACTC1/HNRNPA1/USP46/CAT/CASP3/ABL1/CASP8/APTX/AHR/CRK/CLU/CCL7/SIRT1/PPP1R15B/RGS19/CCND1/TRPM2/SETD7/OSER1/ADCY7/IL6/PDGFB/LRRK2/G6PD/ADCY1/SPARC/ETS1/MIR34A/SETX/OXCT1/SPHK1/RSRC1/SCGB1A1/HDAC2/VKORC1/ZNF580/XRN1/BCL2/ADCY3/PCNA/CDKN1B/SETDB1/CCR4/TYMS/KDM5B/CYBB/HYAL3/TIMELESS/HNRNPD/MAP3K5/GOT2/KDM6B/ADA/FDX1/NFE2L2/IMPACT/TXN/DNMT3A/MAOB/ADAM9/PRKAA1/HAMP/MDM2/CHRNB2/BAD/FOSL1/JAK1/NR4A3/ATP7A/CLDN18/HP/DBH/POLB/GPX1/ND4/RHOA/IL18RAP/PDE8A/PDCD10/SIGMAR1/MET/BAK1/CHUK/MGMT/ENDOG/ADH7/DAXX/ADCYAP1R1/RBP4/HTR3A/PDGFD/FOXO3/MEF2C/ZNF277/RPL10A	152
BP	GO:0001906	cell killing	84/7096	168/18670	0.0009792	0.01118	0.008337	ITGAM/S100A12/PTPN6/SERPINB9/CLEC7A/STX7/CD55/AZU1/GAPDH/CD1C/CEBPG/CTSC/PTPRC/P2RX7/CD1E/LAMP1/CD59/LILRB1/IL7R/CD226/PPP3CB/STXBP2/PRDX1/LEP/FAM49B/HLA-F/CORO1A/HLA-E/HLA-B/CLEC12B/AGER/RASGRP1/CD1B/PIK3R6/CRK/TYROBP/HLA-G/DNASE1/APOL1/CD5L/HLA-C/RPS19/CCL13/BCL2L11/EMP2/FCER2/GZMB/UNC13D/PVR/LAG3/CD1D/IL12RB1/CD1A/LGALS9/PGLYRP4/GZMM/ULBP2/CRTAM/VAV1/KIR2DL4/IL18/FADD/PRF1/AP1G1/HAMP/REG3G/BAD/HLA-A/HAVCR2/IFNG/NCR3/HRG/GNLY/SERPINB4/HSP90AB1/CTSG/IL12B/SH2D1A/MICA/NCR1/IL18RAP/RAB27A/IL23A/CXCL6	84
BP	GO:0106106	cold-induced thermogenesis	73/7096	143/18670	0.0009808	0.01118	0.008337	EPAS1/CCR2/ACOT13/APPL2/ACVR2B/RBPJ/FABP4/STAT6/THRA/HADH/PLAC8/ADIPOR1/ALDH1A1/ABHD6/LGR4/PER2/IL4R/CEBPB/JAK2/IL15/ZNF516/ATF4/CPT2/ARRDC3/IL18R1/IP6K1/SCD/CD36/LEP/NR1H2/TLR4/ZBTB7B/DECR1/PDGFC/ADRB1/IGF1R/VEGFA/CMKLR1/OMA1/UCP2/GATM/TFE3/G0S2/PPARGC1A/FLCN/GRB10/PLCL1/FH/NR1H3/ADRB2/FFAR4/KSR2/KDM6B/UCP1/FABP5/IL18/ADAM17/ADIPOR2/PLCL2/ARNTL/OGT/RB1/DBH/MFAP2/ELOVL6/SLN/DIO2/WNT10B/GJA1/ALMS1/TRPV2/GHRL/PRKAB1	73
BP	GO:0120161	regulation of cold-induced thermogenesis	73/7096	143/18670	0.0009808	0.01118	0.008337	EPAS1/CCR2/ACOT13/APPL2/ACVR2B/RBPJ/FABP4/STAT6/THRA/HADH/PLAC8/ADIPOR1/ALDH1A1/ABHD6/LGR4/PER2/IL4R/CEBPB/JAK2/IL15/ZNF516/ATF4/CPT2/ARRDC3/IL18R1/IP6K1/SCD/CD36/LEP/NR1H2/TLR4/ZBTB7B/DECR1/PDGFC/ADRB1/IGF1R/VEGFA/CMKLR1/OMA1/UCP2/GATM/TFE3/G0S2/PPARGC1A/FLCN/GRB10/PLCL1/FH/NR1H3/ADRB2/FFAR4/KSR2/KDM6B/UCP1/FABP5/IL18/ADAM17/ADIPOR2/PLCL2/ARNTL/OGT/RB1/DBH/MFAP2/ELOVL6/SLN/DIO2/WNT10B/GJA1/ALMS1/TRPV2/GHRL/PRKAB1	73
BP	GO:0031342	negative regulation of cell killing	16/7096	22/18670	0.001004	0.01134	0.008458	SERPINB9/PTPRC/LILRB1/IL7R/PPP3CB/HLA-F/HLA-E/CLEC12B/CRK/HLA-G/LGALS9/KIR2DL4/HAVCR2/SERPINB4/HSP90AB1/MICA	16
BP	GO:0032402	melanosome transport	16/7096	22/18670	0.001004	0.01134	0.008458	BBS5/RAB11A/MLPH/MYO5A/ASIP/BLOC1S6/BBS2/MKKS/BBS4/BLOC1S3/DCTN2/BBS7/GPR143/MREG/CDH3/RAB27A	16
BP	GO:0043496	regulation of protein homodimerization activity	16/7096	22/18670	0.001004	0.01134	0.008458	ARF6/PCBD1/TICAM1/SYAP1/NRG1/ITGA4/HSPA5/BCL2/BAX/TRAF2/GNL3L/TIRAP/BAK1/TRAF4/AIDA/MEF2C	16
BP	GO:0045624	positive regulation of T-helper cell differentiation	16/7096	22/18670	0.001004	0.01134	0.008458	NFKBIZ/ANXA1/NLRP3/IL4R/SOCS5/NFKBID/IL12RB1/HLX/IL18/TNFSF4/IL12B/PRKCZ/CD80/CCL19/MALT1/IL23A	16
BP	GO:0051195	negative regulation of cofactor metabolic process	16/7096	22/18670	0.001004	0.01134	0.008458	CBFA2T3/FYN/FBP1/STAT3/NUPR1/MPV17L/PPARGC1A/SLC25A12/MYOG/PFKFB1/HDAC4/MMP3/DDIT4/PPARA/HP/CTNS	16
BP	GO:0002228	natural killer cell mediated immunity	37/7096	64/18670	0.001007	0.01134	0.008458	PTPN6/SERPINB9/CEBPG/LAMP1/LILRB1/CD226/PRDX1/LEP/HLA-F/CORO1A/HLA-E/CLEC12B/RASGRP1/PIK3R6/CRK/HLA-G/CD96/GZMB/UNC13D/PVR/LAG3/LGALS9/ULBP2/CRTAM/VAV1/KIR2DL4/IL18/AP1G1/HAVCR2/NCR3/SERPINB4/IL12B/SH2D1A/MICA/NCR1/IL18RAP/RAB27A	37
BP	GO:0046579	positive regulation of Ras protein signal transduction	37/7096	64/18670	0.001007	0.01134	0.008458	IGF1/RTN4R/LYN/NOTCH2/RASGEF1A/KITLG/ALS2/P2RY8/JAK2/SHOC2/AKAP13/KRAS/ARRB1/NRG1/EPOR/HRAS/RASGRP1/SHC1/RAC1/MAPRE2/LPAR6/IRS2/STK19/GPR18/GRB2/LPAR1/F2R/RASGRF1/VAV1/GPR35/APOA1/SYNPO2L/MAP4K4/P2RY10/GPR20/MMD2/RASGRP4	37
BP	GO:0097164	ammonium ion metabolic process	100/7096	205/18670	0.001016	0.01142	0.008517	ITGAM/ASAH1/LPCAT2/SLC27A1/SMS/CDS1/SLC22A4/PLA2G12A/SGMS2/GCH1/NR4A2/POR/ENPP2/CBR4/SRD5A1/AKR1B1/ALDH9A1/CHPT1/CAPN2/ABHD4/ALDH7A1/APOC1/SCARB1/PLA2G7/MBOAT1/PLBD1/AKR1C3/CETP/HNMT/SAT1/PNPLA6/AKR7A2/CSNK2A2/STARD10/PNKD/AKR1A1/PRKCD/ACADM/SGPP2/MAOA/AKR1C1/SPTLC2/PAFAH1B1/ODC1/SAMD8/PLA2G15/CLN3/LDLR/PLB1/CSNK2B/STARD7/FABP3/DAO/ABHD3/RAB38/APOA5/PNPLA8/ENPP7/HDAC10/SPHK1/MFSD2A/PLA2G3/MBOAT2/LCAT/TMEM86B/SGMS1/BHMT/CPT1A/AZIN1/CHKA/AKR1B10/SHMT1/FABP5/TPH2/MAOB/DBI/ACER3/KDSR/CHRNB2/APOA1/SRM/PLA2G6/ATP7A/SLC44A2/SMPD1/DBH/CROT/SNCAIP/LRTOMT/CHAT/SNCA/AZIN2/LPCAT1/CHKB/SMPD2/CHDH/AGMAT/DHPS/DEGS2/LPCAT3	100
BP	GO:0097237	cellular response to toxic substance	118/7096	247/18670	0.001027	0.01153	0.008594	KLF4/NQO1/S100A9/KLF2/KCNMB1/ANXA1/GCH1/ALOX5AP/SPI1/PINK1/AIFM1/SOD1/STAT6/PTGS2/PLEKHA1/TNFAIP3/ADH5/MGST2/GSTP1/PSAP/EGR1/TNF/EZH2/HMOX1/GSR/NFKB1/APOE/TXNRD1/GPX7/RELA/AXL/ACTB/CYP1B1/HGF/FIS1/ESD/MAP1LC3A/CD36/PRDX1/TXNDC17/MAPK7/AKR1A1/PCGF2/PRKCD/HBB/MAPK13/NET1/HNRNPA1/CAT/ABL1/GSTO1/GSTZ1/GPX3/IPCEF1/GSTA1/CCL7/SIRT1/BMP7/GPX4/TRPM2/OSER1/ADCY7/IL6/PDGFB/GSTM3/LRRK2/RDH12/PPARGC1A/ETS1/MIR34A/SETX/SPHK1/HDAC2/MGST1/ZNF580/XRN1/DNM2/PCNA/PRDX6/HBQ1/CYBB/TIMELESS/MAP3K5/KDM6B/AKR1B10/NFE2L2/IMPACT/DHFR/TXN/SESN1/DNMT3A/PRKAA1/MGST3/MDM2/BAD/NR4A3/ATP7A/HP/OPRD1/MSX1/GPX1/IL18RAP/PDE8A/PDCD10/SRXN1/SIGMAR1/MET/HBE1/ENDOG/MPO/NNT/DAXX/SESN2/PTGS1/PDGFD/FOXO3/ALB/ZNF277	118
BP	GO:0008286	insulin receptor signaling pathway	72/7096	141/18670	0.001047	0.01173	0.008747	SH2B2/ATP6V0D2/PDK4/SOCS3/TSC1/ATP6AP1/PTPN2/CCND3/ATP6V1C1/ADIPOR1/C2CD5/ATP6V0C/CISH/GSK3B/GAB1/PIK3R3/GKAP1/RELA/PDK2/SLC2A8/CDK4/PAK1/ENHO/LEP/PRKCD/INSR/BAIAP2/TCIRG1/ZBTB7B/IGF1R/NCK1/ATP6V1A/IL1B/SIK2/SHC1/PHIP/ATP6V1G3/SIRT1/EIF4EBP2/ATP6V1B2/IRS2/ATP6V1D/GRB10/GNAI2/ATP6V0E2/INPP5K/GPR21/RHOQ/KANK1/NDEL1/GRB2/FOXO4/FER/ATP6V1G2/SERPINA12/KL/PRKAA1/PID1/SOCS1/ZNF106/OGT/SLA2/PRKCZ/PRKCQ/ATP6V1B1/SMARCC1/APPL1/SOCS2/NUCKS1/NR1H4/STXBP4/FOXO3	72
BP	GO:0001787	natural killer cell proliferation	9/7096	10/18670	0.001086	0.01208	0.009009	ELF4/IL15/LEP/FLT3LG/PTPN22/HLA-E/IL18/IL12B/IL23A	9
BP	GO:0009157	deoxyribonucleoside monophosphate biosynthetic process	9/7096	10/18670	0.001086	0.01208	0.009009	DGUOK/CDADC1/TK1/TYMS/DCK/SHMT1/TK2/DCTD/DUT	9
BP	GO:0034427	nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'	9/7096	10/18670	0.001086	0.01208	0.009009	EXOSC2/EXOSC7/DIS3L2/EXOSC9/EXOSC3/EXOSC6/SKIV2L/EXOSC8/EXOSC5	9
BP	GO:0072641	type I interferon secretion	9/7096	10/18670	0.001086	0.01208	0.009009	LILRB1/DDX58/DHX9/MMP12/HMGB1/MAVS/IFIH1/CHUK/HMGB4	9
BP	GO:0045576	mast cell activation	35/7096	60/18670	0.001095	0.01217	0.009072	S100A12/RAC2/LYN/PLSCR1/IL4R/HMOX1/C12orf4/LCP2/CD226/STXBP1/LAT2/STXBP2/FGR/RASGRP1/CD300LF/NDRG1/S100A13/PLA2G3/ADORA2B/PIK3CD/UNC13D/CD300A/LGALS9/FER/RABGEF1/CNR2/RHOH/IL13RA2/CD84/TSLP/NR4A3/PIK3CG/SNX4/FOXF1/LAT	35
BP	GO:0035304	regulation of protein dephosphorylation	71/7096	139/18670	0.001118	0.0124	0.009242	LILRB2/PINK1/TSC1/CAMTA1/PPP1R15A/MGAT5/JAK2/PTPRC/SHOC2/TNF/GSK3B/CABIN1/PPP4R2/TGFB1/PHACTR2/PPP2R3A/PHACTR1/PPP1R16A/PPP1R26/SWAP70/PPP6R1/PRKCD/PPP1R14A/ELFN1/PPP1R37/RCAN3/PPP1R2/SLC39A10/PPP1R14B/SYMPK/PPP1R15B/PPP1R16B/MFHAS1/CDH5/PPP2R5C/ANKLE2/GNAI2/PPP2R2D/BOD1L1/PPP2R2B/ELFN2/PPP1R3B/RCAN1/CD300A/PPP4R1/PPP1R36/PPP1R7/MYOZ1/NSMF/PPP2R1B/EIF2AK2/PPP1R11/HSP90B1/YWHAE/IGBP1/LMTK2/MASTL/PIN1/B3GAT3/SMPD1/PPP1R14D/HSP90AB1/PPP2R5B/PHACTR4/SET/CD33/CDCA2/MTOR/ROCK2/BOD1/PPP2R2C	71
BP	GO:0002407	dendritic cell chemotaxis	17/7096	24/18670	0.001127	0.01241	0.009251	CCR2/CCL5/HMGB1/TRPM4/TRPM2/CXCR1/CCR5/CCR6/LGALS9/CALR/C1QBP/CXCR2/PIK3CG/GPR183/CCL19/CCR7/SLAMF8	17
BP	GO:0071677	positive regulation of mononuclear cell migration	17/7096	24/18670	0.001127	0.01241	0.009251	FPR2/CCR2/LGMN/PLA2G7/TNF/CXCL10/CXCL12/TGFB1/AIF1/AGER/CCL5/HMGB1/MOSPD2/SERPINE1/CREB3/PDGFD/S100A14	17
BP	GO:0002483	antigen processing and presentation of endogenous peptide antigen	12/7096	15/18670	0.001132	0.01241	0.009251	TAP2/TAP1/HFE/HLA-F/HLA-E/HLA-B/HLA-G/TAPBP/HLA-C/ERAP1/HLA-A/ERAP2	12
BP	GO:0006000	fructose metabolic process	12/7096	15/18670	0.001132	0.01241	0.009251	FBP1/AKR1B1/PFKFB3/ALDH1A1/ALDOC/ALDOA/PFKFB4/KHK/PFKFB1/SORD/PFKFB2/GLYCTK	12
BP	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	12/7096	15/18670	0.001132	0.01241	0.009251	TAP2/TAP1/HFE/HLA-F/HLA-E/HLA-B/HLA-G/TAPBP/HLA-C/ERAP1/HLA-A/ERAP2	12
BP	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase	12/7096	15/18670	0.001132	0.01241	0.009251	ACAA1/SCP2/ACOX1/ECI2/HSD17B4/ACOX2/DECR2/EHHADH/ACOX3/CROT/ABCD1/ACOT8	12
BP	GO:0034616	response to laminar fluid shear stress	12/7096	15/18670	0.001132	0.01241	0.009251	KLF4/KLF2/SMAD7/TGFB1/MAPK7/ABCA1/ETS1/SREBF2/NFE2L2/ADAM9/TGFB3/MAP2K5	12
BP	GO:0051258	protein polymerization	133/7096	283/18670	0.001162	0.01271	0.009477	MYADM/CDC42EP4/VASP/ARF6/STMN1/PINK1/DIAPH1/HCK/RHOBTB1/PLEKHG2/PSTPIP1/JAK2/TMSB10/SPIRE1/IQGAP2/ACTR2/TMOD3/HCLS1/GAS7/EVL/PSRC1/MX2/UBE2K/TWF2/RDX/PFN1/CDC42EP2/PAK1/UBE2S/CLIP1/PTK2B/RANBP9/CAPZA2/CSNK1D/PRKCD/LATS1/GMFG/CORO1A/BAIAP2/ARFGEF1/CAPG/NCK1/PSTPIP2/ABL1/FCHSD1/CDK5RAP2/AIF1/ARPC1A/CAPZA1/MAPRE1/TPPP3/GPX4/MKKS/RAC1/ARPIN/SPTBN1/TTBK1/ARPC1B/CDC42EP3/CDH5/CYFIP1/MYO1C/ZNF207/CORO1B/ARHGAP6/MAP7D3/BBS4/ARF1/ARPC5L/COTL1/AVIL/CHMP2A/MICALL2/CDKN1B/TUBGCP3/MX1/CKAP5/KANK1/TRIOBP/ARHGAP18/ADD3/NDEL1/TTC17/RANGRF/GRB2/VDAC2/JMY/ACTR3B/FER/UBE2C/DMTN/SLC39A12/DNM1L/ACTR3/MSRB1/TUBG2/CLASP2/LMOD3/TUBGCP5/CAV3/SCIN/PREX1/SLIT2/CCL26/TUBB4A/CASQ1/ARPC4/CASQ2/SPTA1/SLAIN2/SPTBN2/ARPC2/TRIM6/KANK3/MTOR/NAV3/RHOA/TRPV4/PICK1/SNCA/CLIP3/SNX9/MET/FGF13/CCR7/WAS/RHOBTB2/CCL24/TPPP/BIN1/NCKAP1/FCHSD2/FMN1	133
BP	GO:0009266	response to temperature stimulus	116/7096	243/18670	0.001166	0.01273	0.009492	IGF1/MYOF/FOS/HTR2B/SLC27A1/METRNL/CDKN1A/APPL2/LYN/IER5/SOD1/TMEM135/HSPA6/NUP62/NUP160/THRA/PTGS2/LRP11/PLAC8/LXN/NUP214/DNAJA4/NFKBIA/ZNF516/HMOX1/SLC9A1/CXCL10/IGFBP7/GSK3B/CXCL12/DNAJB1/NUP85/HSF2/SEH1L/RPA1/HTRA2/EIF2B5/NUP43/ADRB1/HSF4/HSPA5/RBBP7/GCLC/CASP8/UCP2/DNAJC2/POM121/SIRT1/TRPM2/EIF2S1/MLST8/PPARGC1A/FGF1/DNAJB6/SUMO1/PTGES3/RBM3/ATM/DNAJC7/DNAJB4/HDAC2/HSBP1/MAPKAPK2/NUP88/PRKACA/NUP107/IL1A/ADRB2/AKT1S1/YBX3/ACADVL/CAMK2A/POLR2D/UCP1/STUB1/HSPA1L/ATXN3/NFE2L1/CAMK2D/NUP93/ATR/CETN1/BAG2/ATP2A2/CHORDC1/PRKAA1/NUP205/MAPK1/YWHAE/CASQ1/EIF2B1/EPHB1/NUP50/TGFB1I1/DNAJA1/CD34/EIF2B3/HSP90AB1/EIF2AK4/MICA/VCP/MTOR/TRPV4/BAG5/HSBP1L1/EIF2B2/ATXN3L/DAXX/ST8SIA1/NR2F6/TRPV3/POM121C/AAAS/TRPV2/NTSR1/CAMK2B	116
BP	GO:0050821	protein stabilization	88/7096	178/18670	0.001179	0.01285	0.009582	IGF1/CDKN1A/GRN/PINK1/TNIP2/TSC1/PIM1/CDC37L1/GAPDH/CHP1/HPS4/FLNA/SMAD7/ZBED3/FBXW7/FLOT1/WDR81/LAMP2/LAMP1/TESC/CDC37/STXBP1/PFN1/CRTAP/GTPBP4/GNAQ/WFS1/PRKCD/USP9X/CCNH/NLK/CREB1/CLU/SAV1/TYROBP/CREBL2/ATP1B2/IFT46/PPARGC1A/FLOT2/ZNF207/SUMO1/PTGES3/ATP1B3/ATP1B1/TMEM88/PEX19/CCT4/USP27X/NAPG/FKBPL/CALR/NAA16/CCT8/MUL1/BAG2/USP7/DVL1/TELO2/STX12/APOA1/TAF9B/NCLN/OTUD3/SWSAP1/MTMR9/PIN1/HSP90AB1/COG7/MSX1/TBL1X/PER3/NAA15/MCM8/TSPAN1/ZSWIM7/RTN4/PIM2/SOX4/BAG5/PDCD10/USP19/PPIB/UBE2B/WNT10B/SMO/STXBP4/CSN3	88
BP	GO:0022029	telencephalon cell migration	33/7096	56/18670	0.001183	0.01288	0.009603	SUN2/MBOAT7/CXCL12/ARL13B/SRF/NRG1/FBXO45/CDK5/PAFAH1B1/SRGAP2C/P2RY12/LRRK2/ARX/DIXDC1/SYNE2/SRGAP2/NRP1/DISC1/NRP2/PEX13/NDEL1/DAB1/CDK5R2/EGFR/SLIT2/PSEN1/NR2E1/RELN/RHOA/RTN4/EFHC1/FGF13/LHX6	33
BP	GO:0032147	activation of protein kinase activity	154/7096	333/18670	0.001189	0.01292	0.009632	IGF1/NOD2/FPR1/PEA15/PRKAR2B/DUSP6/ACVR2B/PINK1/SLC11A1/OXSR1/WNT5A/DUSP5/SOD1/ERP29/TNFRSF10A/STRADB/ZFP91/MAP2K1/PRR5/DUSP7/RGCC/JAK2/MAP3K8/PTPRC/P2RX7/ALK/UBE2N/TNF/PRKACB/CD74/GPRC5B/ERCC6/MAP3K4/MAPKAPK3/TAOK3/GADD45B/HGF/ARRB1/PAK1/MAP4K5/PTK2B/LEP/PRKCD/INSR/TAB3/NRG1/TRAF6/IKBKG/TLR4/DBF4B/PDGFC/BMP2/VEGFA/CARD14/ABL1/PAK2/IL1B/CSPG4/TOM1L1/CCL5/MAP3K12/MDFIC/SHC1/ATG13/PDE6G/CRK/RAF1/SLK/CHI3L1/DUSP19/MAP4K2/CCDC88A/MAP4K3/ADCY7/MLST8/PDGFB/LRRK2/FGF1/ADCY1/PROK1/MAPKAPK5/PRKAG2/EMP2/TAB1/ADORA2B/ADCY3/MAPKAPK2/BMP4/MARK2/MAP3K6/PRKACA/MAP4K1/LPAR3/ADRB2/PPP2R3C/MLKL/UBC/MAP2K2/MAP3K11/CD300A/BIRC7/LPAR1/MAP3K5/PROK2/F2R/MOS/TNFRSF10B/EIF2AK2/EGFR/TXN/MUL1/IL18/TRAF2/ADAM9/PRKAA1/PSEN1/MAPK1/SOCS1/MAP2K4/CLSPN/TGFB3/MAP3K13/PRRC1/MAPK11/RET/MAP3K1/MAPKAP1/TLR3/MAP2K5/CARD10/IL12B/PRKCZ/MAP4K4/MTOR/COPS8/ERN1/ITGB1BP1/CCL19/MALT1/TIRAP/NEK4/TRAF4/FGF13/GHR/STRADA/GREM1/DAXX/IL23A/TLR6/KIF14/GHRL/PIK3CB/NRK/MAP3K9	154
BP	GO:0140053	mitochondrial gene expression	81/7096	162/18670	0.001193	0.01293	0.009636	MRPS6/ALKBH1/MTERF1/TRMT5/MRPL35/MRPL45/UQCC1/CHCHD1/MRPL40/MTIF2/MRPS30/MRPL34/LARS2/MTERF2/MRPS16/UQCC2/MRPS14/TRMT61B/CHCHD10/MRPL54/MRPL44/PUS1/MRPL33/IARS2/SHMT2/MRPL51/HSD17B10/OXA1L/TEFM/GFM2/MTRF1L/MRPL49/MRPL3/NOA1/MRPL42/TBRG4/DAP3/COA3/C1QBP/SLC25A33/MRPS34/NGRN/PRKAA1/MRPL4/GADD45GIP1/MRPS33/SUPV3L1/MTIF3/RPUSD3/MRPL20/MRPL46/MRPS18B/MRPL24/MRPL36/MRPS25/YARS2/DARS2/MRPS15/QRSL1/MRPL48/MTRF1/POLRMT/MTO1/AURKAIP1/MRPL41/PNPT1/MRPL2/TRMT10C/GFM1/MPV17L2/MRPS2/MRPS9/AARS2/FOXO3/NDUFA7/WARS2/MRPL30/MRPL1/FASTKD5/MRRF/MRPS17	81
BP	GO:0034605	cellular response to heat	70/7096	137/18670	0.001194	0.01293	0.009636	MYOF/CDKN1A/LYN/IER5/HSPA6/NUP62/NUP160/PTGS2/NUP214/HMOX1/CXCL10/GSK3B/DNAJB1/NUP85/HSF2/SEH1L/RPA1/HTRA2/NUP43/HSF4/HSPA5/RBBP7/DNAJC2/POM121/SIRT1/EIF2S1/MLST8/FGF1/DNAJB6/SUMO1/PTGES3/ATM/DNAJC7/HDAC2/HSBP1/MAPKAPK2/NUP88/PRKACA/NUP107/IL1A/AKT1S1/CAMK2A/POLR2D/STUB1/HSPA1L/ATXN3/CAMK2D/NUP93/ATR/CETN1/BAG2/ATP2A2/CHORDC1/NUP205/MAPK1/YWHAE/NUP50/CD34/HSP90AB1/VCP/MTOR/TRPV4/BAG5/HSBP1L1/ATXN3L/DAXX/ST8SIA1/POM121C/AAAS/CAMK2B	70
BP	GO:0035966	response to topologically incorrect protein	97/7096	199/18670	0.001235	0.01333	0.009935	EXTL2/LMNA/HSPA6/TPP1/PTPN2/TMBIM6/PPP1R15A/FBXO6/CREBRF/FKBP14/KLHL15/ATF4/TMEM129/EDEM1/TLN1/DNAJB1/WFS1/HSPB1/SSR1/RNF175/HSPA5/NCK1/HERPUD2/TMEM33/PARP16/CREB3L2/DNAJB5/UBE2W/SHC1/ERP44/WIPI1/VAPB/CLU/PPP1R15B/CCND1/EIF2S1/TOR1B/SDF2L1/GOSR2/EDEM2/CREB3L4/SERP1/DNAJB4/TOR1A/PDIA6/KDELR3/BCL2L11/STT3B/BAX/CTH/ASNS/RNF126/DNAJC4/DERL1/CREB3/TM7SF3/ACADVL/DNAJB9/CANX/DERL2/STUB1/CALR/HSPA1L/NFE2L2/ATXN3/EIF2AK2/YOD1/CTDSP2/HSP90B1/HSPA4/GFPT1/BFAR/POMT2/TBL2/DNAJA1/HYOU1/RNF185/HSP90AB1/RNF5/PPP2R5B/YIF1A/OPTN/VCP/MANF/MBTPS2/ERN1/BAK1/MBTPS1/EDEM3/ATXN3L/PREB/DAXX/ARFGAP1/HSPB3/DNAJC18/HDGF/ATF6B	97
BP	GO:0050866	negative regulation of cell activation	97/7096	199/18670	0.001235	0.01333	0.009935	CCR2/PTPN6/LILRB2/ANXA1/GRN/LYN/IRF1/ARG2/GPNMB/MNDA/LST1/PTPN2/TNFRSF14/BCL6/SMAD7/TNFAIP3/BANK1/FGL2/IL4R/CEBPB/CBFB/PTPRC/HFE/CD74/HMOX1/TNFRSF21/APOE/LILRB1/DUSP3/AXL/TGFB1/SOCS5/PRKCD/HLA-F/TSPAN32/IL20RB/PTPN22/ZBTB7B/SOCS6/ABR/DTX1/CASP3/IDO1/GCLC/NFKBID/LDLR/CD300LF/HMGB1/THBD/TYROBP/HLA-G/PDGFB/CTLA4/GLMN/BCR/CST7/ATM/TIGIT/VSIG4/SCGB1A1/PDCD1LG2/NRARP/BMP4/PARP3/ID2/NR1H3/LAG3/INHBA/CD300A/CD274/RHBDD3/LGALS9/LAX1/PDGFA/PGLYRP4/FER/RABGEF1/BTN2A2/CNR2/HLX/TNFRSF13B/TNFSF4/IL13RA2/MERTK/PAG1/SOCS1/CD84/HAVCR2/INHA/SLA2/MICA/CD80/TBX21/TYRO3/CX3CL1/FOXF1/TWSG1	97
BP	GO:0031529	ruffle organization	31/7096	52/18670	0.001268	0.01366	0.01019	ARF6/PLEKHA1/SNX10/LIMA1/EVL/RDX/PFN1/RHOG/HRAS/FAM98A/AIF1/P2RY12/RAC1/PLEKHM1/CYFIP1/SH3YL1/CORO1B/TPM1/WDPCP/INPP5K/KANK1/NDEL1/PLEK/CORO1C/RCC2/TACSTD2/EPS8L2/CSF1R/MTOR/CCR7/INPPL1	31
BP	GO:0009260	ribonucleotide biosynthetic process	137/7096	293/18670	0.001271	0.01367	0.01019	IGF1/CBFA2T3/HK3/PDK4/UPP1/LDHA/PINK1/FBP1/PGK1/CBR4/VPS9D1/STAT3/PFKFB3/NUP62/NUP160/PFKM/PFKP/GAPDH/PANK2/NUP214/ACOT7/PAPSS1/ACSL5/SLC2A6/P2RX7/ELOVL5/NUPR1/AK3/PGAM1/AK2/PKM/PDK2/GALK1/EIF6/TPI1/ZBTB7A/TGFB1/GMPS/NUP85/HIF1A/SCD/SEH1L/PANK3/ADK/INSR/ALDOC/PANK1/GUK1/PAICS/NUP43/IMPDH1/ACSL4/CTPS2/ACLY/ENO1/DNAJC30/ALDOA/GSTZ1/CMPK1/TECR/POM121/MPC2/ACACB/RFK/OGDH/ELOVL7/GPI/ADCY7/PFKFB4/PPARGC1A/FLCN/MLYCD/ADCY1/DHTKD1/NME3/ACSL6/SLC25A12/LDHC/NME4/PRKAG2/MYOG/NCOR1/PFKFB1/ATIC/ADCY3/NUP88/HDAC4/PAPSS2/NME1/NUP107/PDK1/PPAT/PDHB/FOXK2/DDIT4/AMPD2/PGK2/PFKFB2/ARNT/DLAT/PDP2/UCK1/PPARA/NUP93/SLC25A13/PRKAA1/PSEN1/PDHA2/NUP205/ENO2/PID1/GUCY2D/SLC4A1/TREM2/CTPS1/CAD/NUP50/IFNG/PRKAG1/OGT/PDP1/ESRRB/ZBTB20/VCP/ADPGK/UCKL1/TAZ/APP/SNCA/ELOVL6/UPP2/AMPD3/PDPR/PFKL/POM121C/AAAS/HSD17B12	137
BP	GO:0050921	positive regulation of chemotaxis	69/7096	135/18670	0.001274	0.01367	0.01019	FPR2/CCR2/RAC2/OXSR1/WNT5A/AZU1/VEGFB/CAMK1D/S1PR1/LGMN/PLA2G7/CD74/CXCL10/CXCL12/TGFB1/MEGF8/HSPB1/PTK2B/SWAP70/CXCL13/VEGFA/CMKLR1/AIF1/AGER/CCL5/P2RY12/HMGB1/CCL7/PPM1F/RAC1/IL6/PDGFB/IL16/C3AR1/MOSPD2/GPSM3/NRP1/ZNF580/TMEM102/PRKD2/SERPINE1/CCR6/ITGA2/CREB3/CCR4/LGALS9/SEMA5A/LPAR1/CALR/C1QBP/CXCR2/ADAM17/SLIT2/CCL26/TREM2/SUCNR1/LBP/F3/TRPV4/DAPK2/CCL19/MET/TIRAP/CCL4/CCR7/IL23A/PDGFD/S100A14/BMPR2	69
BP	GO:0072330	monocarboxylic acid biosynthetic process	158/7096	343/18670	0.001275	0.01367	0.01019	IGF1/ALOX5/CBFA2T3/HK3/PDK4/RBP1/ANXA1/VCAN/ALOX5AP/LDHA/FBP1/PGK1/STARD4/CYP27A1/CBR4/STAT3/PFKFB3/NUP62/NUP160/PFKM/PTGS2/PFKP/GAPDH/ADIPOR1/MIF/RDH10/OSBPL9/NUP214/ACOT7/SLC45A3/PER2/APOC1/SLC2A6/ACSM5/P2RX7/MGLL/DEGS1/CD74/ELOVL5/SCP2/NUPR1/AKR1C3/LPGAT1/PGAM1/PKM/GALK1/EIF6/TPI1/DHRS9/ZBTB7A/OSBPL1A/NUP85/HIF1A/ABCD3/SCD/HPGD/SEH1L/MYO5A/OXSM/NR1H2/ERLIN1/INSR/ALDOC/NUP43/FADS3/ACLY/ENO1/IDO1/ALDOA/IL1B/CSPG4/TECR/ERLIN2/POM121/SLC27A2/HSD17B4/ACACB/OGDH/ACOX2/ASNSD1/ELOVL7/SIRT1/GPX4/GPI/PFKFB4/PPARGC1A/ABHD3/DECR2/CHST14/MLYCD/APOA5/PNPLA8/PTGES3/DHTKD1/SLC25A12/ALOX15B/LDHC/PRKAG2/MYOG/NCOR1/CYP2D6/CYP1A2/PFKFB1/SCAP/NUP88/HDAC4/ALDH8A1/ASNS/NR1H3/NUP107/CH25H/OSBPL2/HPGDS/FOXK2/ABCB11/DDIT4/ACADVL/BCAN/GSTM4/PGK2/PFKFB2/ARNT/INSIG1/FABP5/BRCA1/PPARA/NUP93/ADIPOR2/PRKAA1/PSEN1/NUP205/ENO2/SLC4A1/SRR/NUP50/IFNG/PRKAG1/OGT/CHST12/ESRRB/ZBTB20/ADPGK/APP/ELOVL6/ABCD1/CRABP2/PFKL/PLP1/CYP46A1/CYP2C8/NR1H4/FADS2/POM121C/AAAS/PTGS1/HSD17B12/ACOT8/PRKAB1	158
BP	GO:0001961	positive regulation of cytokine-mediated signaling pathway	30/7096	50/18670	0.001308	0.01393	0.01038	TRIM32/IRF7/PARP9/WNT5A/NLRC5/CREBRF/CD74/AXL/UBE2K/HIF1A/PAFAH1B1/MMP12/CD300LF/IL7/IL1R1/MAVS/LSM14A/CASP1/ZBP1/FADD/ADAM17/TRAF2/CASP4/CPNE1/TREM2/TSLP/TXK/TRIM6/AGPAT1/AGPAT2	30
BP	GO:0032608	interferon-beta production	30/7096	50/18670	0.001308	0.01393	0.01038	TLR2/IRF7/IRF1/FLOT1/LILRB1/TICAM1/REL/NMI/TLR4/DDX58/TRAF3/CACTIN/RELB/DHX9/MAVS/DDX3X/IFIH1/HMGB2/YY1/TLR8/RIOK3/NLRX1/TLR3/TRAF3IP1/ZBTB20/POLR3F/RNF216/TIRAP/NLRC3/RNF135	30
BP	GO:0072698	protein localization to microtubule cytoskeleton	30/7096	50/18670	0.001308	0.01393	0.01038	NUP62/DIAPH1/SNX10/ABHD17C/GSK3B/GOLGB1/PCM1/CSNK1D/CEP131/UBXN2B/KIAA0753/NSFL1C/MAPRE1/SPAG5/MAPRE2/BICD1/BBS4/CHAMP1/DISC1/HOOK3/KIF20B/DCTN2/MID2/CRIPT/DVL1/MAP1A/CEP83/AURKA/TTBK2/C2CD3	30
BP	GO:0060260	regulation of transcription initiation from RNA polymerase II promoter	19/7096	28/18670	0.001308	0.01393	0.01038	DR1/THRA/ZNF451/SRF/PSMC4/HMGB1/SUB1/CREB1/PSMC3/CAND1/PSMC6/HEY2/HNF1B/HNF1A/PSMC5/PSMC2/PAXIP1/WNT10B/TAF7	19
BP	GO:0016999	antibiotic metabolic process	76/7096	151/18670	0.001312	0.01396	0.0104	FYN/RAC2/NANP/PINK1/SOD1/CBR4/MDH1/AKR1B1/STAT3/GNPDA1/ALDH1A1/NPL/ADH5/HAL/AKR1C3/AKR7A2/ESD/PRDX1/PCK2/NAGK/AKR1A1/HBB/MPV17L/AKR1C1/RENBP/CAT/ACLY/ALDH2/ME3/GPX3/OGDH/IDH1/ACO1/RAC1/NOXA1/ALDH5A1/IDH2/DHTKD1/CYP1A2/FH/PRDX6/MDH1B/MMP3/HBQ1/PDHB/CYBA/CYBB/IREB2/CMAS/SUCLG2/AKR1B10/DLAT/ADH1B/EGFR/IDH3A/MAOB/PDHA2/ST3GAL1/AMDHD1/FAHD1/HP/SDHA/DUOXA1/SULT1B1/GPX1/GNE/SDHD/ME2/IDH3G/SNCA/SDHAF2/HBE1/CTNS/MPO/NNT/ADH7	76
BP	GO:0070302	regulation of stress-activated protein kinase signaling cascade	114/7096	239/18670	0.001324	0.01405	0.01048	NOD2/EZR/DUSP1/LYN/PINK1/WNT5A/ZNF622/SH3RF1/DUSP10/MAP2K1/MYC/GSTP1/FAS/DVL2/TNF/ERCC6/ZEB2/MAP3K4/HMGCR/SLAMF1/DUSP3/TAOK3/GADD45B/HGF/PAK1/MAP4K5/PTK2B/PRDX1/LEP/ROR2/TRAF6/NCF1/TLR4/PTPN22/TPD52L1/BMP2/IGF1R/VEGFA/HRAS/PAFAH1B1/IL1B/DTNBP1/SEMA4C/AGER/MAP3K12/RASGRP1/SDCBP/MDFIC/HMGB1/TNFRSF11A/IL1RN/MFHAS1/DUSP19/MAP4K2/CYLD/RELL2/SPHK1/NCOR1/EDAR/MAP3K6/MAP4K1/ZMYND11/MLKL/MAP2K2/MAP3K11/SH3RF3/FZD5/AMBP/BIRC7/MAP3K5/ZMPSTE24/PLCB1/EIF2AK2/EGFR/MUL1/CAV3/TRAF2/FZD4/MAPK1/MAP2K4/MAP3K13/PPEF2/IGBP1/EPHB1/HIPK3/DNAJA1/ANKRD6/ULK4/TLR3/FZD7/MEN1/MAP4K4/TRPV4/APP/ERN1/PDCD4/PDCD10/CCL19/TIRAP/NBR1/TRAF4/AIDA/WNT7A/CCR7/PRMT1/IL26/DAXX/SERPINF2/TLR6/FZD10/NRK/SASH1/IL37/MAP3K9	114
BP	GO:0002573	myeloid leukocyte differentiation	99/7096	204/18670	0.001328	0.01407	0.01049	JUNB/FOS/SIGLEC15/CBFA2T3/TLR2/SPI1/SBNO2/LYN/IRF7/NOTCH2/RBPJ/ATP6AP1/PTPN2/PIR/KLF10/BATF3/LILRB3/KITLG/SNX10/FBXW7/MYC/CEBPB/IL15/BATF/TNF/CD74/SH3PXD2A/TESC/LILRB1/HCLS1/TGFB1/ROR2/OSCAR/LILRB4/TRAF6/TCIRG1/TLR4/CEBPA/VEGFA/RELB/PAFAH1B1/CASP8/MITF/TNFRSF11A/CREB1/SIRT1/TYROBP/TFE3/GAB3/TAL1/OSTM1/MYH9/TMEM64/BATF2/MMP9/BMP4/PIK3CD/ID2/NME1/INHBA/EVI2B/IREB2/THOC5/PIAS3/FADD/TFRC/ANXA2P2/PSEN1/DCSTAMP/LRRC17/EIF2AK1/TREM2/IL25/C1QC/IFNG/CLDN18/CD4/RB1/TLR3/INHA/IL12B/CSF1R/ANXA2/MTOR/PRTN3/FOXP1/APP/GPR183/SLC9B2/CCL19/EFNA2/TSPAN2/CCR7/HOXA7/PRKCA/IL23A/APCS/CD109/MEF2C	99
BP	GO:0045069	regulation of viral genome replication	51/7096	95/18670	0.001332	0.01409	0.0105	PLSCR1/OASL/IFITM2/TNF/IFITM1/IFITM3/MORC2/ISG20/STAU1/DDB1/ADARB1/OAS3/IFI27/RSAD2/CCL5/SRPK2/ISG15/VAPB/APOBEC3G/MAVS/APOBEC3C/IFIT5/DDX3X/ILF3/BANF1/ZC3HAV1/TARBP2/BCL2/CCL8/TBC1D20/TNIP1/INPP5K/CCNK/MX1/TOP2B/SETDB1/RNASEL/IFIT1/SRPK1/EIF2AK2/CNOT7/PKN2/FMR1/FBXL2/TRIM6/EIF2AK4/ADAR/PPIB/NUCKS1/TOP2A/BTBD17	51
BP	GO:0097421	liver regeneration	20/7096	30/18670	0.001368	0.01445	0.01077	SRSF5/CEBPB/HFE/EZH2/HMOX1/CSNK2A2/TGFB1/RAP1A/CSNK2B/CCND1/SULF2/PCNA/TYMS/PRMT5/EGFR/HAMP/WDR35/AURKA/PNPT1/PTCH1	20
BP	GO:0050706	regulation of interleukin-1 beta secretion	28/7096	46/18670	0.001378	0.01451	0.01082	NOD2/WNT5A/ARG2/LILRA5/NLRP3/TNFAIP3/LILRA2/NLRP12/P2RX7/AIM2/TRIM16/PANX1/SERPINB1/TLR4/PML/HMGB1/CASP1/LGALS9/FZD5/CPTP/TLR8/APOA1/NLRP1/NLRP2/FOXP1/CCL19/CCR7/HMGB4	28
BP	GO:0097720	calcineurin-mediated signaling	28/7096	46/18670	0.001378	0.01451	0.01082	IGF1/ATP2B4/CAMTA1/CHP1/CIB1/TNF/SLC9A1/GSK3B/DYRK2/PPP3CB/NFATC3/MAPK7/NRG1/RCAN3/HOMER3/LMCD1/NFATC1/NFATC2/RCAN1/NFAT5/MYOZ1/FHL2/EFHB/CHP2/LACRT/MTOR/CHERP/ERBB3	28
BP	GO:1901800	positive regulation of proteasomal protein catabolic process	55/7096	104/18670	0.0014	0.0147	0.01096	CBFA2T3/TMTC3/SMAD7/KEAP1/DDRGK1/FBXW7/BCAP31/NUPR1/GSK3B/RNF19B/EDEM1/SGTA/ZFAND2A/SOCS5/CSNK1D/RNF217/CEBPA/PLK2/ANKIB1/GCLC/PSMC4/CLU/EDEM2/LRRK2/SUMO1/HSPBP1/CSNK1A1/CSNK1E/RNFT1/ARIH2/PLK3/UBQLN2/TRIB2/BBS7/DET1/NKD2/KLHL40/STUB1/NFE2L2/ATXN3/BAG2/DVL1/PSEN1/FMR1/MDM2/PSMC1/TREM2/RNF185/PSMC2/VCP/AURKA/RBX1/KCNE2/CHFR/MAPK9	55
BP	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	55/7096	104/18670	0.0014	0.0147	0.01096	IGF1/ITPRIP/FYN/PEA15/GCLM/LMNA/TNFRSF10A/SH3RF1/STRADB/EYA3/TNFAIP3/GSTP1/FAS/TNF/HMOX1/RELA/HGF/CTNNA1/MAPK7/MCL1/TNFSF10/GCLC/CASP8/IL1B/ARHGEF2/PHIP/IL7/TRADD/RAF1/BMP5/NRP1/PSME3/BCL2/BMP4/SERPINE1/HMGB2/IL1A/ZMYND11/UNC5B/RFFL/TNFRSF10B/BRCA1/FADD/COL2A1/TRAF2/ZC3HC1/TCF7L2/EYA4/FAIM2/MAP2K5/TERT/GPX1/CX3CL1/FAIM/SIAH2	55
BP	GO:0000375	RNA splicing, via transesterification reactions	174/7096	382/18670	0.001404	0.01471	0.01097	CELF6/TRA2B/PCF11/NSRP1/JMJD6/SRSF5/PRPF4/DDX20/PRPF38A/U2SURP/KHDRBS1/CSTF3/HNRNPR/METTL14/HNRNPH1/ALYREF/PPIL1/DAZAP1/RNPS1/THRAP3/HNRNPH3/RBM7/MAGOHB/ZBTB7A/PCBP1/RBM42/SRSF10/CWF19L2/LSM5/CRNKL1/WDR83/METTL3/HNRNPK/MBNL1/YTHDC1/RBM4/RBM4B/COIL/SYF2/SNRNP25/SNRNP200/CWF19L1/HNRNPA1/CACTIN/HNRNPA2B1/RBM8A/SNUPN/SNRPB/GEMIN6/TXNL4A/DHX9/U2AF1/GTF2F2/SRPK2/LUC7L/SFSWAP/SRSF3/GEMIN7/SNRPA1/RNF113A/BCAS2/POLR2L/SYMPK/BUD31/SFPQ/HNRNPUL1/DHX8/CPSF3/RBM41/PDCD7/MBNL3/CLP1/CD2BP2/POLR2H/RBMXL1/PAPOLA/LSM7/SNIP1/RBM3/SNRPD1/PRPF3/USP4/SETX/SNRPA/PUF60/SNRPC/DCPS/ZCCHC8/MFAP1/ISY1/RSRC1/CWC22/SNRPB2/HNRNPC/FIP1L1/STRAP/PRPF40B/PRPF40A/FUS/HNRNPA0/LUC7L2/SRSF6/PRDX6/SREK1/SNRPF/SRSF7/DDX1/DDX46/RALY/CDC40/PRPF8/PCBP2/SF3A3/GTF2F1/CWC25/SMNDC1/SF3B4/CSTF1/SRPK1/HNRNPD/POLR2F/WEE2-AS1/PRMT5/AAR2/HNRNPM/POLR2D/TGS1/PRPF31/RBMXL2/C1QBP/U2AF1L4/RBMX2/SART1/SRRM1/POLR2K/FMR1/LOC100128988/CELF2/WDR77/USP49/UBL5/SRSF4/WBP11/ZC3H10/RBM25/CLNS1A/DHX38/HNRNPA3/SUGP1/GPKOW/CPSF2/PRPF19/CELF3/HMX2/SRRM4/PRPF39/SAP18/CPSF1/SNRPN/ZCRB1/AQR/CPSF7/PPWD1/IK/CHERP/SRRT/DHX16/EFTUD2/POLR2I/LUC7L3/SYNCRIP/SNRPG/SON/SNRPD2	174
BP	GO:1903955	positive regulation of protein targeting to mitochondrion	21/7096	32/18670	0.001411	0.01476	0.011	RAC2/PINK1/HPS4/FBXW7/CSNK2A2/UBE2D3/HTRA2/ATG13/RHOU/PDCD5/ARIH2/ABLIM3/MICALL2/UBL4B/SREBF2/FZD5/HSPA1L/PRKAA1/SH3GLB1/UBL5/BAP1	21
BP	GO:0006903	vesicle targeting	50/7096	93/18670	0.001416	0.01478	0.01102	SERPINA1/F5/MCFD2/KLHL12/CTSC/SEC22B/CD59/ANKRD28/SAR1B/TRAPPC6A/CSNK1D/PPP6R1/FAM91A1/WDR11/CNIH3/TRAPPC5/CTSZ/ARFGAP3/TMED10/C17orf75/STARD3NL/WIPI1/BET1/MAP4K2/GOSR2/AP1M2/GOSR1/STX5/SAR1A/PPP6C/TRAPPC6B/TRAPPC9/NAPA/TBC1D20/COL7A1/LMAN1/PEF1/YKT6/CLASP2/SEC23IP/TRAPPC2L/PSEN1/CEP19/TRAPPC3/EXOC4/SCFD1/SNAP29/PREB/SEC24A/SEC16B	50
BP	GO:0046365	monosaccharide catabolic process	38/7096	67/18670	0.001417	0.01478	0.01102	HK3/PGK1/PFKM/PFKP/GAPDH/GALM/ALDH1A1/CRYL1/GALE/FUT4/FUT7/PGAM1/LRP5/PKM/GALK1/RPE/TPI1/AKR1A1/DHDH/ALDOC/ENO1/ALDOA/GPI/SLC25A12/PGM2/KHK/NUDT5/FUT6/GALT/FOXK2/SORD/PFKFB2/ENO2/BAD/ADPGK/GLYCTK/PFKL/RBKS	38
BP	GO:0051701	interaction with host	101/7096	209/18670	0.001423	0.01481	0.01104	CLEC5A/TRIM32/SERPINB9/ATG7/CD55/WWP1/ITGA5/ITGB7/FCN1/GAPDH/ITGB5/TNFRSF14/SLC22A5/F11R/SCARB1/IFITM2/LAMP1/IFITM1/CD74/TRIM13/VPS37B/IFITM3/ALYREF/SLAMF1/DPP4/AXL/CHMP4B/TGFB1/XPR1/INSR/NCAM1/PTX3/HYAL2/TRIM26/KPNA4/DDB1/CD209/CASP8/LDLR/CTSB/PML/VAPB/TRIM11/CR1/CCR5/CBLL1/SELPLG/BCL2L11/RXRA/TRIM21/VPS18/CCL8/TNIP1/NEDD4/CHMP2A/THOC2/CCNK/TSG101/PVR/IST1/LGALS1/ITGA2/CR2/GRB2/TYMS/SLC10A1/LGALS9/IFIT1/HYAL3/VPS4B/RRAGA/THOC5/GPR15/EIF2AK2/EGFR/WWP2/MID2/TFRC/THOC6/SLC20A2/SIVA1/KPNA1/BAD/SMC3/TNFRSF4/FUCA2/TRIM15/CD4/EIF2AK4/PC/CD80/TYRO3/DAG1/CDHR3/MET/KPNB1/HAVCR1/MOG/APCS/EXOC2/CLDN6	101
BP	GO:0097028	dendritic cell differentiation	26/7096	42/18670	0.00143	0.01485	0.01107	LILRB2/SPI1/LYN/RBPJ/BATF3/CEBPB/BATF/LILRB1/AXL/TGFB1/TRAF6/FLT3/RELB/AGER/HMGB1/TRPM2/HLA-G/AZI2/BATF2/LGALS9/PSEN1/DCSTAMP/TREM2/PRTN3/CCL19/CCR7	26
BP	GO:0006099	tricarboxylic acid cycle	22/7096	34/18670	0.001438	0.01485	0.01107	MDH1/ME3/OGDH/IDH1/ACO1/IDH2/DHTKD1/FH/MDH1B/PDHB/IREB2/SUCLG2/DLAT/IDH3A/PDHA2/FAHD1/SDHA/SDHD/ME2/IDH3G/SDHAF2/NNT	22
BP	GO:0017004	cytochrome complex assembly	22/7096	34/18670	0.001438	0.01485	0.01107	SCO2/COA5/UQCC1/COX19/COX20/UQCC2/TIMM21/UQCR10/COX16/OXA1L/LYRM7/COA6/COX15/CYBA/PET100/COA3/COA4/SLC25A33/SURF1/COX14/UQCRB/SMIM20	22
BP	GO:0043368	positive T cell selection	22/7096	34/18670	0.001438	0.01485	0.01107	STAT6/STAT3/PTPN2/LY9/PTPRC/BATF/CD74/SRF/CD3D/IL6/CYLD/BCL2/CD3G/IL12RB1/THEMIS/BCL11B/IL12B/TBX21/MTOR/FOXN1/CD3E/IL23A	22
BP	GO:0045920	negative regulation of exocytosis	22/7096	34/18670	0.001438	0.01485	0.01107	CCR2/ANXA1/RAP1B/HMOX1/HLA-F/ABR/RAP1A/RAB33B/BCR/GNAI2/CD300A/LGALS9/VPS4B/RABGEF1/FMR1/IL13RA2/CD84/IL1RAPL1/STXBP3/SYT4/SNCA/FOXF1	22
BP	GO:0002369	T cell cytokine production	25/7096	40/18670	0.001446	0.01488	0.0111	CCR2/CD55/SLC11A1/NLRP3/SMAD7/HFE/DENND1B/IL18R1/HLA-F/TRAF6/CLC/RSAD2/IL1B/TRPM4/IL1R1/IL6/FZD5/IL18/TRAF2/TNFSF4/IL12B/PRKCZ/TBX21/IL18RAP/MALT1	25
BP	GO:0035735	intraciliary transport involved in cilium assembly	25/7096	40/18670	0.001446	0.01488	0.0111	IFT172/TNPO1/IFT57/KIF3B/KIFAP3/PCM1/DYNLL2/CEP131/IFT80/WDR19/IFT46/IFT52/HSPB11/DYNC2LI1/DYNLRB1/DYNLRB2/IFT20/KIF17/WDR60/IFT22/WDR35/TRAF3IP1/IFT74/TTC30B/IFT81	25
BP	GO:0006266	DNA ligation	13/7096	17/18670	0.001448	0.01488	0.0111	APTX/HMGB1/XRCC4/XRCC1/PARP3/HMGB2/LIG4/XRCC6/LIG3/POLB/APLF/MGMT/TOP2A	13
BP	GO:2000516	positive regulation of CD4-positive, alpha-beta T cell activation	23/7096	36/18670	0.001452	0.0149	0.01111	NFKBIZ/ANXA1/CD55/NLRP3/IL4R/SOCS5/ZBTB7B/NFKBID/IL12RB1/LGALS9/HLX/IL18/TNFSF4/SOCS1/IFNG/IL12B/PRKCZ/CD80/PRKCQ/CD83/CCL19/MALT1/IL23A	23
BP	GO:0002707	negative regulation of lymphocyte mediated immunity	24/7096	38/18670	0.001454	0.0149	0.01111	PTPN6/SERPINB9/BCL6/SMAD7/PTPRC/HFE/LILRB1/IL7R/PPP3CB/HLA-F/IL20RB/HLA-E/CLEC12B/CRK/HLA-G/CR1/CD96/PARP3/LGALS9/KIR2DL4/HAVCR2/SERPINB4/MICA/TBX21	24
BP	GO:0001558	regulation of cell growth	188/7096	416/18670	0.00146	0.01491	0.01111	IGF1/S100A9/S100A8/RTN4R/FN1/TRIM32/CDKN2D/CDKN1A/DPYSL2/MAD2L2/FBP1/PPP2CA/OSGIN1/WNT5A/SEMA4B/CHPT1/RASGRP2/ADNP2/SPP1/BCL6/RAB11A/PPARD/ADIPOR1/RPS6KA3/CIB1/ULK2/RGS2/SLC9A1/IFRD1/CISH/IGFBP7/APOE/GSK3B/PLAA/CXCL12/TMC8/SH3BP4/PSRC1/TWF2/TGFB1/SIN3A/PAK1/MEGF8/IGFBP4/PTK2B/OSGIN2/BCL11A/ADAM15/SRF/HYAL2/NDUFS3/OGFR/SEMA4A/NET1/PARP2/RBBP7/VEGFA/CDK5/TNFRSF12A/SFN/KLHL22/ABL1/ENO1/PAFAH1B1/NDRG3/GDI1/PTCH2/LAMTOR1/SEMA4C/EBAG9/SDCBP/PML/SEMA4D/LRP1/SIRT1/CDKN2AIP/TMEM97/CTDP1/ACVR1B/DCC/G6PD/EIF4G2/CYFIP1/FLCN/DNPH1/DDX3X/WFDC1/SEMA6B/SPHK1/ING1/BTG1/NRP1/DISC1/SEMA3B/BCL2/DNM2/EI24/KDM2B/EXOSC2/L1CAM/CDKN1B/CDKN2C/YY1/TSG101/LPAR3/IST1/FHL1/NDEL1/INHBA/OLFM1/CYBA/ST20/WDR36/SEMA5A/MMP14/FSTL4/DERL2/SERTAD2/CAMK2D/EGFR/MUL1/SLC25A33/PPARA/ADAM17/CAV3/ITSN2/SLIT2/ADIPOR2/HAMP/TCHP/SEMA5B/DCSTAMP/SUPV3L1/CYP27B1/TAF9B/LTBP4/EIF4G1/RASAL1/DCUN1D3/MAP3K13/RUFY3/EXOSC9/PLXNA3/SPOCK1/NAIF1/BAP1/FGFR1OP/HRG/SYT1/CPNE9/PIN1/HBEGF/BDKRB1/RB1/MAP2K5/SYT2/JADE1/MSX1/CDA/SYT4/MTOR/PRKCQ/HPN/RHOA/RTN4/CDC73/CRABP2/RIMS2/LMX1A/FGF13/DCBLD2/SOCS2/CLSTN3/GJA1/IL17RB/KIAA1109/SESN2/WT1/KIF14/MACF1/PRSS2/TRPV2/KAZALD1/TRIM46/PTPRJ/PRDM11/BMPR2/SLIT3	188
BP	GO:0050730	regulation of peptidyl-tyrosine phosphorylation	121/7096	256/18670	0.00146	0.01491	0.01111	IGF1/FYN/PTPN6/BST1/SOCS3/LYN/PPP2CA/PARP9/FCGR1A/ENPP2/ITGA5/STAT3/PTPN2/LILRA5/TNFRSF14/NEDD9/BANK1/CD40/KITLG/MIF/FBXW7/CD44/JAK2/PTPRC/IL15/DVL2/TNF/CD74/GPRC5B/ERCC6/HCLS1/LRP8/TGFB1/HGF/CBLB/SOCS5/CD36/ZFYVE28/PTK2B/LEP/PRKCD/RAP2C/NRG1/ZGPAT/HYAL2/NCF1/FLT3/PDGFC/VEGFA/EHD4/ABL1/PAK2/RAP2B/CSPG4/MVP/PTK6/CCL5/ARHGEF2/SHC1/SEMA4D/IL7/SH3BP5L/TNFRSF18/IL6ST/IL6/PDGFB/SPINK1/TAL1/SNX6/HDAC2/NRP1/TMEM102/CLCF1/TSG101/TEC/OSM/CD300A/INPP5F/PDGFA/DMTN/HES1/VPS25/CNTF/EGFR/CNOT7/IL18/ADAM17/PSEN1/SOCS1/TREM2/IL3/TSLP/IFNG/FGFR1OP/HRG/TNFSF18/HBEGF/CD4/LACRT/PPP2R5B/IL12B/PRKCZ/RELN/CD80/CSF1R/MTOR/APP/ARL2BP/LRP4/GHR/CD3E/GREM1/CD24/ERBB3/IL23A/CNTN1/PDGFD/GHRL/NTRK2/PTPRJ/MIR146A	121
BP	GO:0072678	T cell migration	37/7096	65/18670	0.001489	0.01518	0.01132	MYO1G/CCR2/IL27RA/OXSR1/WNT5A/ITGB7/TNFRSF14/S1PR1/CXCL11/ADAM8/CXCL10/CXCL12/DOCK8/CXCL13/ITGA4/CD99/AIF1/CCL5/CRK/CD200R1/SLC12A2/CD99L2/TMEM102/PIK3CD/CCR6/GPR15/FADD/ADAM17/CCL20/CCL26/MSN/C10orf99/PIK3CG/RHOA/APP/GPR183/CXCR3	37
BP	GO:0031668	cellular response to extracellular stimulus	126/7096	268/18670	0.001512	0.01539	0.01147	FOS/VDR/FYN/USF2/NAMPT/PDK4/UPP1/CDKN1A/ATG7/NR4A2/LYN/AIFM1/TSC1/SOD1/SRD5A1/PIM1/KLF10/PTGS2/PMAIP1/GAS2L1/SIK1/ATG14/FOLR2/LAMP2/GDAP1/GSTP1/PTPRC/IL15/FAS/P2RX7/HFE/HMOX1/SKP2/AKR1C3/ATF4/PDK2/AXL/WDR24/HIGD1A/XPR1/NUDT1/MAP1LC3A/SEH1L/LEP/BCL11A/SRF/BAIAP2/ITGA4/HSPA5/HNRNPA1/CDKN2B/PPM1D/AIF1/SIK2/RRAGD/P2RY12/WIPI1/NPRL3/SIRT1/TRPM4/EIF2S1/KPTN/LRRK2/MAP1LC3C/NMRAL1/FNIP1/ZFYVE1/TRIM24/MYBBP1A/MAPK8/ADORA2B/BCL2/ASNS/WDR45B/CTSV/CYBA/CYBB/TNRC6A/SREBF2/MAP3K5/RRAGA/DNM1L/NFE2L2/IMPACT/EIF2AK2/ULK1/DSC2/ITFG2/AMIGO1/SESN1/HSP90B1/AQP3/PRKAA1/DNAJC15/MDM2/MAPK1/MTMR3/P2RY4/SH3GLB1/CYP27B1/NPRL2/EIF4G1/DAP/TBL2/FOSL1/DAPL1/GABARAPL1/CLEC16A/CACNB3/WNT2B/EIF2AK4/DCTPP1/ASGR1/CADPS2/MTOR/PICK1/DEPDC5/CIB2/SSH1/FGF23/NR1H4/SESN2/UCN3/P2RY1/ALB/BMPR2	126
BP	GO:0007254	JNK cascade	103/7096	214/18670	0.00152	0.01545	0.01152	NOD2/PTGER4/PINK1/WNT5A/SH2D3C/ZNF622/SH3RF1/DUSP10/GSTP1/UBE2N/DVL2/TNF/ERCC6/ZEB2/MAP3K4/SLAMF1/DUSP3/IRAK4/TAOK3/GADD45B/PAK1/MAP4K5/PTK2B/ROR2/TAB3/TRAF6/IKBKG/NCF1/TLR4/PTPN22/TPD52L1/IGF1R/HRAS/ARHGEF6/PAFAH1B1/IL1B/DTNBP1/AGER/MAP3K12/RASGRP1/SDCBP/MDFIC/HMGB1/TNFRSF11A/IL1RN/MFHAS1/DUSP19/MAP4K2/MAP4K3/CYLD/NCOR1/MAPK8/TAB1/ADORA2B/EDAR/MAP3K6/MAP4K1/ZMYND11/MLKL/UBC/MAP3K11/SH3RF3/FZD5/AMBP/BIRC7/MAP3K5/PLCB1/EGFR/MUL1/TRAF2/FZD4/MAP2K4/MAP3K13/PPEF2/EPHB1/HIPK3/DNAJA1/ANKRD6/ULK4/TLR3/FZD7/MEN1/MAP4K4/GPS1/TRPV4/APP/ERN1/PDCD4/CCL19/TIRAP/TRAF4/AIDA/WNT7A/CCR7/DAXX/SERPINF2/TLR6/FZD10/NRK/MAPK9/SASH1/IL37/MAP3K9	103
BP	GO:0009308	amine metabolic process	70/7096	138/18670	0.001531	0.01554	0.01159	NQO1/ITGAM/SMS/ATP2B4/NR4A2/OAZ2/PSMB9/PSMB8/GDE1/SIRT4/ALDH7A1/PSMA5/PSMD11/SLC7A11/HNMT/SAT1/PSME1/SLC7A7/SULT1C2/PSMB10/PSMA1/PNKD/PSMA4/NAPEPLD/OAZ3/MAOA/IDO1/PSMB1/ODC1/PSMC4/PSMD13/PSMB3/KYNU/HAAO/PSMB5/PSMD6/HDAC10/PSMC3/PSME3/PSMC6/BHMT/AZIN1/CHKA/TPH2/IDO2/MAOB/CHRNB2/PSMC1/SRM/PSMD8/PSMA2/ATP7A/SULT1B1/DBH/PSMC5/PSMC2/PSMB2/PSMD4/SNCA/AZIN2/ATCAY/CHDH/AGMAT/PSMD1/DHPS/PSMB4/TDO2/NR1H4/PSMD9/PSMD3	70
BP	GO:0030433	ubiquitin-dependent ERAD pathway	43/7096	78/18670	0.001549	0.0157	0.0117	RNF103/FBXO6/BCAP31/TRIM13/TMEM129/EDEM1/UBE4B/SGTA/WFS1/SEC61B/ERLIN1/RNF175/HSPA5/FOXRED2/UBE2J1/ERLIN2/UBE2G2/EDEM2/UBXN8/NPLOC4/STT3B/UBQLN2/PSMC6/MAN1B1/DNAJC10/DERL1/DNAJB9/DERL2/STUB1/NFE2L2/YOD1/HSP90B1/TMUB2/FBXO27/FBXO44/RNF185/RNF5/VCP/USP19/EDEM3/DNAJC18/ERLEC1/OS9	43
BP	GO:0010770	positive regulation of cell morphogenesis involved in differentiation	77/7096	154/18670	0.001553	0.0157	0.01171	MYADM/S100A10/FN1/SKIL/RAB11A/NEDD9/FLNA/MAP2K1/CIB1/ARHGDIA/ZEB2/ACTR2/CXCL12/PLXNB2/LRP8/TWF2/PAK1/MEGF8/SS18L2/PLXNC1/SRF/BAIAP2/VEGFA/TNFRSF12A/ABL1/PAFAH1B1/GDI1/SEMA4D/ANKRD27/LRP1/CRK/RAC1/CAPRIN1/KALRN/CYFIP1/DOCK5/PLXNA1/NRP1/DISC1/PLXND1/DNM2/L1CAM/UNC13D/LPAR3/TRIOBP/IST1/NDEL1/SEMA5A/DMTN/BHLHB9/DNM1L/CALR/C1QBP/AMIGO1/SS18L1/PREX1/SLIT2/SHOX2/APOA1/MAP3K13/RUFY3/PLXNA3/TRAK1/IL1RAPL1/PLXNA2/ARPC2/RELN/CHODL/RHOA/LIMS1/PARP6/CRABP2/MACF1/TRPV2/NTRK2/CAMK2B/BMPR2	77
BP	GO:1903052	positive regulation of proteolysis involved in cellular protein catabolic process	62/7096	120/18670	0.001555	0.0157	0.01171	CBFA2T3/TMTC3/SMAD7/KEAP1/DDRGK1/FBXW7/CTSC/RNF139/BCAP31/NUPR1/GSK3B/MAGEF1/RNF19B/EDEM1/SGTA/ZFAND2A/SOCS5/PTK2B/CSNK1D/RNF217/CEBPA/PLK2/ANKIB1/GCLC/PSMC4/CLU/EDEM2/LRRK2/SUMO1/PTK2/HSPBP1/CSNK1A1/CSNK1E/RNFT1/ARIH2/PLK3/DISC1/UBQLN2/TRIB2/BBS7/DET1/NKD2/KLHL40/STUB1/NFE2L2/ATXN3/CAV3/BAG2/DVL1/PSEN1/FMR1/MDM2/PSMC1/TREM2/RNF185/PSMC2/VCP/AURKA/RBX1/KCNE2/CHFR/MAPK9	62
BP	GO:0007040	lysosome organization	35/7096	61/18670	0.001638	0.01647	0.01228	SRPX/HEXB/GRN/TPP1/NAGLU/FAM160A2/HPS4/P2RX7/CLN8/ARSB/NAGPA/ZKSCAN3/CORO1A/TFEB/GNPTAB/HPS1/ABCA1/LAMTOR1/CLN3/VPS33A/RAB20/HOOK2/TMEM106B/LRRK2/CLVS2/ARF1/HOOK3/VPS18/MFSD8/CLN6/CLN5/RAB7B/LAPTM4B/GAA/MBTPS1	35
BP	GO:0050701	interleukin-1 secretion	35/7096	61/18670	0.001638	0.01647	0.01228	NOD2/IL1R2/WNT5A/ARG2/LILRA5/NLRP3/TNFAIP3/LILRA2/NLRP12/P2RX7/GBP5/AIM2/TRIM16/CD36/PANX1/SERPINB1/TLR4/ABCA1/PML/HMGB1/S100A13/CASP1/LGALS9/FZD5/CPTP/TLR8/APOA1/NLRP1/NLRP2/FOXP1/CCL19/CCR7/HMGB4/TLR6/IGHD	35
BP	GO:0080171	lytic vacuole organization	35/7096	61/18670	0.001638	0.01647	0.01228	SRPX/HEXB/GRN/TPP1/NAGLU/FAM160A2/HPS4/P2RX7/CLN8/ARSB/NAGPA/ZKSCAN3/CORO1A/TFEB/GNPTAB/HPS1/ABCA1/LAMTOR1/CLN3/VPS33A/RAB20/HOOK2/TMEM106B/LRRK2/CLVS2/ARF1/HOOK3/VPS18/MFSD8/CLN6/CLN5/RAB7B/LAPTM4B/GAA/MBTPS1	35
BP	GO:0007568	aging	148/7096	321/18670	0.0017	0.01706	0.01272	NQO1/FOS/TPRA1/KCNMB1/NAMPT/CDKN1A/ATG7/GCLM/LMNA/SOD1/RETN/ARG2/STAT3/NUP62/JUND/PTGS2/TIMP2/BCL6/BCL2A1/CISD2/MIF/MAP2K1/CTSC/IL15/KRAS/HMGCR/RELA/TGFB1/SMC5/SIN3A/CLN8/EEF1E1/COQ7/NUDT1/CTNNA1/VASH1/SMC6/LEP/COL4A2/PRKCD/SRF/ZKSCAN3/NFKB2/MBD1/MNT/HYAL2/NAPEPLD/LOXL2/HTRA2/EIF2B5/MBD3/CDKN2B/PLK2/CAT/HRAS/NPM1/ABL1/GCLC/NSMCE2/HMGA1/AGER/CDKN1C/PML/LRP1/CREB1/IGFBP2/SIRT1/GPX4/HLA-G/EIF2S1/SERPING1/YPEL3/LRRK2/PPARGC1A/KYNU/SERP1/ATM/MIR34A/RPN2/SLC12A2/MAPKAPK5/POLG/BMPR1A/BCL2/SCAP/SERPINE1/ERCC1/ID2/CASP2/TIMP1/KRTAP4-5/GSS/GRB2/TYMS/CTSV/PDX1/PITX3/FOXO4/ZMPSTE24/ADA/CANX/CALR/CACYBP/NFE2L2/FBXO4/KIR2DL4/ATR/DNMT3A/KL/WNT1/PSEN1/HAMP/MAPK1/ERCC2/SRR/TGFB3/PRDM2/ARNTL/TFCP2L1/CNP/CARM1/TERT/POLB/ND4/MTOR/KRT14/KRTAP4-8/APP/LIMS1/DAG1/SNCA/CX3CL1/ENG/PDCD4/PNPT1/PAX5/SLC30A10/BAK1/NEK4/KCNE2/PICALM/ENDOG/MPO/ALDH3A1/P2RY1/FOXO3/ZNF277/MIR146A	148
BP	GO:1903320	regulation of protein modification by small protein conjugation or removal	110/7096	231/18670	0.001706	0.01709	0.01274	NOD2/FYN/BCL10/PINK1/MAD2L2/HMG20A/CHP1/SMAD7/TNFAIP3/ARRDC4/BIRC2/FBXW7/RNF111/PER2/EGR1/UBE2N/SKP2/PLAA/DCUN1D1/TICAM1/RELA/NMI/UBE3A/ARRDC3/GTPBP4/ARRB1/WFS1/UBE2S/FEM1B/RASSF5/PTTG1IP/TRAF6/PTPN22/HSPA5/CDK5/ABL1/GCLC/UBR5/ISG15/CDK9/LRRK2/MYCBP2/GLMN/HSPBP1/OTUD4/PRR7/USP4/DTX3L/SPHK1/PHF23/DCUN1D5/TRIM21/IVNS1ABP/AIMP2/TNIP1/HDAC4/BIRC3/TOLLIP/ADRB2/DERL1/TSPYL5/TBC1D7/PEF1/KLHL40/UBE2C/BIRC7/ARNT/STUB1/DNM1L/RNF20/PIAS3/FBXO4/COMMD1/BRCA1/MUL1/SPOPL/BAG2/PSEN1/FANCM/MTBP/DCUN1D3/CAPN3/UBXN1/OGT/CDC20/UBE2I/DNAJA1/GNL3L/MASTL/PIN1/HSP90AB1/DCUN1D4/FOXF2/VCP/MTOR/TOPORS/HMG20B/SOX4/BAG5/MALT1/XIAP/PAXIP1/CHFR/GNL3/DAXX/RASD2/AVPR2/SIAH2/MAPK9/SASH1	110
BP	GO:0006665	sphingolipid metabolic process	79/7096	159/18670	0.001708	0.01709	0.01274	ASAH1/HEXB/ALDH3A2/SGMS2/CTSA/PPP2CA/GM2A/ESYT2/CSNK1G2/SUMF1/CERS2/PSAP/P2RX7/DEGS1/TNF/ELOVL5/HEXA/FUT7/SUMF2/CLN8/SGPL1/GALC/PRKCD/SGPP2/B4GALT6/CERS5/HTRA2/SERINC1/SPTLC2/SAMD8/PLA2G15/CLN3/TECR/VAPB/ELOVL7/GLA/CERS4/ARV1/ALDH5A1/CREM/ENPP7/ORMDL2/SPHK1/P2RX1/SERINC3/ORMDL3/PRKD2/BAX/PPM1L/SGMS1/B4GALNT1/NAGA/CLN6/FUT6/B4GALT5/UGCG/TEX2/ST8SIA4/CPTP/STS/AGK/ARSA/ST6GALNAC5/ACER3/PRKAA1/KDSR/PLA2G6/CERK/NEU1/ST6GALNAC3/SMPD1/ST6GALNAC6/ELOVL6/SMPD2/SERINC2/ST8SIA1/ST3GAL5/GLTP/DEGS2	79
BP	GO:0051236	establishment of RNA localization	95/7096	196/18670	0.001721	0.01717	0.0128	ZFP36/TSC1/NXF1/SRSF5/NUP62/NUP160/CHTOP/NUP214/FLOT1/ENY2/G3BP2/AGFG1/KHDRBS1/RAN/ALYREF/RNPS1/EIF6/MX2/MAGOHB/SARNP/NUP85/NXT1/CETN3/SEH1L/SIDT1/YTHDC1/BICD2/NUP43/HNRNPA1/NPM1/HNRNPA2B1/PURA/RBM8A/MVP/SNUPN/FYTTD1/DDX19B/DHX9/U2AF1/POM121/ZNF593/SRSF3/SYMPK/XPOT/SFPQ/CPSF3/MYO1C/ATXN2/ARC/ATM/RBM27/TST/FIP1L1/NUP88/THOC2/SRSF6/SRSF7/CKAP5/NUP107/CDC40/NPIPA1/THOC5/POLR2D/TOMM20/NXT2/U2AF1L4/EIF5A/NUP93/ATR/CETN2/LTV1/THOC6/RIOK2/SSB/SRRM1/NUP205/FMR1/PHAX/SRSF4/EIF4E/NUP50/PARP11/DHX38/MCM3AP/PCID2/HNRNPA3/CPSF2/CPSF1/PNPT1/SIDT2/RRS1/POM121C/AAAS/UPF1/RFTN1	95
BP	GO:0006488	dolichol-linked oligosaccharide biosynthetic process	14/7096	19/18670	0.001724	0.01717	0.0128	ALG2/ALG6/DOLK/ALG12/ALG10/DOLPP1/ALG13/NUS1/DHDDS/SRD5A3/ALG14/DPAGT1/ALG8/ALG3	14
BP	GO:0019184	nonribosomal peptide biosynthetic process	14/7096	19/18670	0.001724	0.01717	0.0128	GCLM/MGST2/SLC7A11/GGCT/GCLC/AASDH/HAGH/BDH2/GSS/CNDP2/NFE2L2/GGT7/GGT5/CHAC2	14
BP	GO:0007163	establishment or maintenance of cell polarity	101/7096	210/18670	0.001728	0.01719	0.01281	MPP5/ARF6/WNT5A/LMNA/FAM89B/RAP1B/RNF41/RHOC/CYTH1/SLC9A1/SPDL1/GSK3B/ACTR2/RND3/DOCK8/PARVB/CTNNA1/PAK1/MAP4/ARF4/PTK2B/RHOG/ARFGEF1/CAP1/UBXN2B/PAFAH1B1/CDK5RAP2/OPHN1/SAPCD2/NSFL1C/ARHGEF2/CRK/SH3BP1/CDH5/FLOT2/RHOU/SNX27/CLIC4/KRIT1/PTK2/MYH9/PDZD11/FSCN3/BCCIP/NDC80/WDPCP/CYP26B1/BCAS3/MARK2/RHOQ/KIF20B/CFL1/CKAP5/KANK1/SIPA1L3/NDEL1/CD3G/RHOV/ZW10/RHOF/PARD6B/HES1/SPRY1/ACTR3/RHOH/MOS/CLASP2/LIN7C/GPSM2/JAM3/MPP7/LRRC7/SPRY2/FSCN1/MSN/KIF2C/WEE1/FRMD4A/EPHB1/RUFY3/RHOBTB3/LLGL1/CENPA/MAPKAP1/HSP90AB1/PRKCZ/MISP/CAP2/RHOA/BRSK1/CCL19/AMOTL1/CCL4/FOXF1/FGF13/WNT7A/CCR7/SFRP5/ROCK2/WWC1/LAMA1	101
BP	GO:0032677	regulation of interleukin-8 production	41/7096	74/18670	0.001734	0.01722	0.01284	KLF4/MYD88/NOD2/TLR1/TLR2/ANXA1/CLEC7A/BCL10/WNT5A/CD58/FCN1/CD2/PTPRC/TNF/CD74/ARRB1/FFAR2/TLR5/MAPKBP1/HYAL2/TLR4/DDX58/PTPN22/CACTIN/IL1B/MAVS/ZNF580/PRKD2/SERPINE1/LGALS9/F2R/FADD/TLR8/TLR3/MAP2K5/LBP/CD33/C5AR2/TIRAP/CD244/TLR6	41
BP	GO:0030330	DNA damage response, signal transduction by p53 class mediator	56/7096	107/18670	0.001748	0.01733	0.01292	CDKN1A/PMAIP1/MIF/CD44/RGCC/BATF/CD74/BTG2/EEF1E1/PTTG1IP/TFAP4/PLK2/SFN/SP100/PPM1D/PML/SIRT1/NDRG1/ATM/TNKS1BP1/MUC1/PLK3/KAT5/PCNA/BAX/CRADD/CASP2/CDKN1B/CNOT4/PLAGL1/ARID3A/ZMPSTE24/SPRED1/DYRK3/E2F4/BRCA1/CNOT7/GML/USP10/ATR/MDM2/RBL2/SNAI1/ING4/CNOT10/CARM1/MSX1/TRIAP1/AURKA/SOX4/PAXIP1/PRMT1/SESN2/E2F8/HIC1/FOXO3	56
BP	GO:0006661	phosphatidylinositol biosynthetic process	60/7096	116/18670	0.001772	0.01751	0.01306	FPR2/HTR2B/SLC27A1/CDS1/PLEKHA1/MTMR12/PIGV/PIGP/PIGK/PIK3R3/PTPN13/SACM1L/PIGN/SYNJ1/PITPNM1/FIG4/PLCG2/PIK3R6/PIGF/SYNJ2/CDIPT/PIGB/DPM1/OCRL/PDGFB/GPAA1/SH3YL1/ATM/ARF1/PIGM/PLEKHA8/SBF1/MTMR4/MPPE1/INPP5K/MTMR6/PIK3CD/PI4K2A/RAB5A/PIGQ/MTMR2/INPP5F/PDGFA/PIGO/PIGH/DPM3/MTMR3/PLEKHA3/PIGT/MTMR9/PIK3CG/PIP5K1B/VAC14/PGAP3/INPPL1/ARF3/PGAP1/PIK3CB/IMPA1/PI4KB	60
BP	GO:0031123	RNA 3'-end processing	75/7096	150/18670	0.001772	0.01751	0.01306	PCF11/SRSF5/BARD1/ZC3H14/CHTOP/LSM11/PAF1/CSTF3/ALYREF/RNPS1/MAGOHB/SARNP/INTS5/INTS7/TOE1/RBM8A/U2AF1/SRSF3/SYMPK/ELAC1/USB1/CPSF3/CDK9/RPRD1B/CLP1/INTS8/PAPOLA/SCAF8/RPS21/MTPAP/SNRPA/FBL/FIP1L1/RPRD2/EXOSC2/HSD17B10/THOC2/SRSF6/CPEB1/SRSF7/CDC40/CSTF1/EXOSC7/CPEB3/THOC5/POLR2D/LEO1/RNF20/INTS2/AHCYL1/U2AF1L4/THOC6/SSB/SRRM1/ERI3/SUPV3L1/SRSF4/EXOSC9/EXOSC3/DHX38/FBLL1/CPSF2/CCNT1/APP/CDC73/EXOSC6/CPSF1/PNPT1/TRMT10C/CPSF7/EXOSC8/INTS6/POLR3K/ZNF473/EXOSC5	75
BP	GO:1901532	regulation of hematopoietic progenitor cell differentiation	46/7096	85/18670	0.001806	0.01782	0.01328	PSMB9/PSMB8/KITLG/CBFB/LDB1/PSMA5/PSMD11/PSME1/LMO2/PSMB10/PSMA1/PSMA4/METTL3/ZBTB1/TCF12/ABL1/PSMB1/PSMC4/PSMD13/PSMB3/FLCN/TAL1/PSMB5/PSMD6/PSMC3/FNIP1/N4BP2L2/PSME3/PSMC6/DPF2/OSM/HES1/NFE2L2/EIF2AK2/PSMC1/PSMD8/PSMA2/PSMC5/PSMC2/PSMB2/PSMD4/PUS7/PSMD1/PSMB4/PSMD9/PSMD3	46
BP	GO:0006635	fatty acid beta-oxidation	40/7096	72/18670	0.001834	0.01801	0.01343	HADHB/PPARD/HADH/ACAA1/SCP2/ETFA/CPT2/AUH/ABCD3/LEP/ECH1/ACADM/ACADS/DECR1/ACOX1/ETFDH/ECI2/SLC27A2/HSD17B4/ACACB/ACOX2/IRS2/BDH2/DECR2/MLYCD/ECI1/ETFB/TYSND1/CPT1A/EHHADH/ACADVL/HADHA/PPARA/ACAA2/ACOX3/CROT/MTOR/ABCD1/SESN2/ACOT8	40
BP	GO:0009301	snRNA transcription	40/7096	72/18670	0.001834	0.01801	0.01343	ELL2/NABP1/SNAPC3/POU2F1/POU2F2/INTS5/GTF2E1/INTS7/TAF11/GTF2F2/INTS9/POLR2L/SNAPC1/SNAPC2/ELL3/CDK9/TAF5/RPRD1B/INTS8/POLR2H/RPRD2/CCNK/USPL1/GTF2F1/INTS3/POLR2F/POLR2D/INTS2/GTF2A1/POLR2K/PHAX/RPAP2/TBP/CCNT1/SNAPC4/SRRT/INTS4/ICE1/POLR2I/INTS6	40
BP	GO:1902036	regulation of hematopoietic stem cell differentiation	40/7096	72/18670	0.001834	0.01801	0.01343	PSMB9/PSMB8/CBFB/LDB1/PSMA5/PSMD11/PSME1/LMO2/PSMB10/PSMA1/PSMA4/METTL3/TCF12/ABL1/PSMB1/PSMC4/PSMD13/PSMB3/TAL1/PSMB5/PSMD6/PSMC3/N4BP2L2/PSME3/PSMC6/OSM/NFE2L2/EIF2AK2/PSMC1/PSMD8/PSMA2/PSMC5/PSMC2/PSMB2/PSMD4/PUS7/PSMD1/PSMB4/PSMD9/PSMD3	40
BP	GO:0072329	monocarboxylic acid catabolic process	67/7096	132/18670	0.001867	0.01828	0.01363	ASRGL1/ALDH3A2/HADHB/PPARD/HADH/ACAA1/CRYL1/PHYH/SCP2/FAH/ETFA/CPT2/AUH/ABCD3/PCK2/LEP/AKR1A1/ECH1/ACADM/ACADS/DECR1/MCEE/AIG1/PLA2G15/ACOX1/ETFDH/ECI2/SLC27A2/HSD17B4/ACACB/ACOX2/ACBD5/IDUA/IRS2/BDH2/ABHD3/DECR2/ALDH5A1/MLYCD/PCCB/ECI1/CYP26B1/NUDT19/ETFB/PEX13/TYSND1/CPT1A/EHHADH/SORD/ACADVL/HADHA/AGXT2/NUDT7/PPARA/ACAA2/ACOX3/PGD/CYP26A1/CROT/MTOR/CYP4F3/ABCD1/ABHD16A/HACL1/SESN2/HAO1/ACOT8	67
BP	GO:0002886	regulation of myeloid leukocyte mediated immunity	32/7096	55/18670	0.001872	0.01828	0.01363	ITGAM/CCR2/RAC2/LYN/DDX21/IL4R/HMOX1/C12orf4/TICAM1/STXBP1/PTAFR/STXBP2/DDX58/FGR/ABR/HLA-E/DNASE1/MAVS/BCR/ADORA2B/UNC13D/DDX1/CD300A/LGALS9/FER/RABGEF1/IL13RA2/PRAM1/CD84/SNX4/FOXF1/CXCL6	32
BP	GO:0010823	negative regulation of mitochondrion organization	32/7096	55/18670	0.001872	0.01828	0.01363	IGF1/VAT1/ATG7/PINK1/LMNA/SLC35F6/RNF41/SIRT4/TMEM14A/PRELID1/HIGD1A/HGF/MPV17L/HTRA2/FZD9/OMA1/CLU/SLC25A5/LRRK2/PPARGC1A/FLCN/FNIP1/LMAN1/USP30/DNM1L/MUL1/ACAA2/CLEC16A/LIG3/GPX1/TRIAP1/IAPP	32
BP	GO:0048016	inositol phosphate-mediated signaling	32/7096	55/18670	0.001872	0.01828	0.01363	IGF1/ATP2B4/CAMTA1/CHP1/CIB1/TNF/SLC9A1/GSK3B/DYRK2/PPP3CB/NFATC3/ITPR1/MAPK7/NRG1/RCAN3/HOMER3/GPR62/NMUR2/LMCD1/NFATC1/NFATC2/RCAN1/NFAT5/MYOZ1/FHL2/EFHB/CHP2/LACRT/MTOR/CHERP/ERBB3/INPP5A	32
BP	GO:0072331	signal transduction by p53 class mediator	125/7096	267/18670	0.001904	0.01856	0.01384	CDKN1A/BARD1/PMAIP1/MIF/CD44/SHISA5/RGCC/BATF/FHIT/CD74/NUPR1/BTG2/PDK2/DYRK2/HEXIM1/CSNK2A2/RAD1/EEF1E1/RPA1/PTTG1IP/HNRNPK/USP28/BANP/TFAP4/MBD3/TMEM109/RMI2/RBBP7/CDK5/PLK2/SFN/SP100/PPM1D/TAF11/HINT1/TAF12/PML/RBBP4/CSNK2B/SIRT1/SETD9/NDRG1/ELL3/TAF5/RHNO1/TP53RK/RFC3/ATM/TNKS1BP1/WWOX/MUC1/MAPKAPK5/AEN/HDAC2/PRKAG2/PLK3/TRIM24/KAT5/MYBBP1A/RAD17/BCL2/PCNA/BAX/BRPF1/NOC2L/CRADD/CASP2/CDKN1B/RMI1/RPF2/CNOT4/SSRP1/PLAGL1/ARID3A/PHF20/JMY/RFFL/DDIT4/HIPK1/PRMT5/ZMPSTE24/SPRED1/DYRK3/E2F4/BRCA1/CNOT7/GML/USP10/ATR/RRM2B/PRKAA1/MDM2/TAF9B/EXO1/RBL2/TAF4/SNAI1/RAD9A/PPP1R13B/TOPBP1/MAPK11/PRKAG1/PIN1/ING4/CNOT10/CARM1/MSX1/SUPT16H/TBP/TOPORS/TRIAP1/AURKA/SOX4/MTA2/PAXIP1/PRMT1/ATAD5/RRS1/SESN2/E2F8/HIC1/FOXO3/TAF7/PRKAB1/L3MBTL1	125
BP	GO:0006970	response to osmotic stress	45/7096	83/18670	0.001918	0.01864	0.0139	TSC22D3/AQP9/OXSR1/AKR1B1/PTGS2/TNF/HNMT/PKD2/PTK2B/MAPK13/MBIP/CASP3/RELB/XRCC5/ARHGEF2/ICOSLG/LRRC8D/NOLC1/DDX3X/EFHD1/MLC1/SLC12A2/PLK3/BAX/ITGA2/NFAT5/MICU1/YBX3/SORD/MYLK/LRRC8A/EGFR/LETM1/BAD/XRCC6/CAPN3/HSP90AB1/TLR3/TSC22D2/TSC22D4/SERPINB6/KCNMA1/TRPV4/LRRC8E/SLC12A6	45
BP	GO:0060218	hematopoietic stem cell differentiation	45/7096	83/18670	0.001918	0.01864	0.0139	PSMB9/PSMB8/CBFB/LDB1/PSMA5/BATF/PSMD11/PSME1/LMO2/PSMB10/PSMA1/PSMA4/CHD2/SRF/METTL3/TCF12/ABL1/PSMB1/PSMC4/XRCC5/PSMD13/PSMB3/TAL1/PSMB5/PSMD6/PSMC3/N4BP2L2/PSME3/PSMC6/OSM/NFE2L2/EIF2AK2/PSMC1/ERCC2/PSMD8/PSMA2/PSMC5/PSMC2/PSMB2/PSMD4/PUS7/PSMD1/PSMB4/PSMD9/PSMD3	45
BP	GO:0044843	cell cycle G1/S phase transition	138/7096	298/18670	0.00194	0.01883	0.01404	KLF4/PTPN6/ATP2B4/ANXA1/CDKN2D/CDKN1A/GPNMB/CCND3/CUL1/MCM6/MEPCE/DDRGK1/ZNF655/FBXW7/MYC/MCM2/RGCC/SLFN11/EZH2/LSM11/PAF1/KHDRBS1/SKP2/PKD2/GIGYF2/GMNN/PSME1/BTG2/CCND2/GPR132/CDK4/RDX/ORC5/RPA1/E2F6/LATS1/CDKN2B/PLK2/SFN/PRIM2/CCNH/ZPR1/AIF1/KLF11/PML/CDK2AP2/CCND1/ACVR1B/RCC1/RHOU/DDX3X/ATM/TNKS1BP1/PPP6C/MUC1/KMT2E/CTDSPL/PLK3/PSME3/NACC2/UBE2E2/CCNE1/BCL2/PCNA/ORC6/BAX/USP26/ANKRD17/CRADD/ID2/CASP2/CTDSP1/RFWD3/CDKN1B/CDKN2C/CNOT4/FHL1/CDC25A/INHBA/PPAT/PLAGL1/CACUL1/ARID3A/TYMS/ORC4/RRM2/BTN2A2/CAMK2A/NPAT/E2F4/PLCB1/DHFR/EGFR/CNOT7/GML/ADAM17/CTDSP2/MCM5/MDM2/CCNA1/CUL2/EIF4G1/WEE1/RBL2/MTBP/DCUN1D3/EIF4E/BACH1/LATS2/NASP/CUL4B/TMEM14B/RB1/C10orf99/CCNA2/MEN1/CNOT10/POLA1/CARM1/JADE1/POLA2/ORC3/TERT/ESRRB/MCM8/HINFP/TRIAP1/AURKA/PIM2/CDC73/SOX4/POLE4/PRMT1/USP37/STXBP4/KIF14/E2F8/SUSD2	138
BP	GO:0019682	glyceraldehyde-3-phosphate metabolic process	15/7096	21/18670	0.001953	0.01887	0.01407	TALDO1/ALDH1A1/PGAM1/RPE/TPI1/TKT/RPIA/G6PD/PGM2/KHK/DERA/PGD/GLYCTK/PGLS/RBKS	15
BP	GO:0035590	purinergic nucleotide receptor signaling pathway	15/7096	21/18670	0.001953	0.01887	0.01407	P2RY14/P2RY8/P2RX7/PTAFR/P2RY6/GPR171/P2RY12/GPR34/P2RX1/P2RY13/P2RY4/P2RY10/P2RX2/P2RY1/P2RX5	15
BP	GO:0046386	deoxyribose phosphate catabolic process	15/7096	21/18670	0.001953	0.01887	0.01407	NEIL2/UNG/NUDT1/NT5C/SAMHD1/TDG/PGM2/DERA/ADA/DCTPP1/NT5M/DUT/NUDT16/MBD4/SMUG1	15
BP	GO:0030099	myeloid cell differentiation	187/7096	416/18670	0.002015	0.01942	0.01448	JUNB/EPAS1/FOS/SIGLEC15/CLEC5A/KLF2/CBFA2T3/TLR2/PTPN6/DLL1/SPI1/SBNO2/LYN/IRF7/ZFP36/NOTCH2/RBPJ/JMJD6/ATP6AP1/STAT3/PTPN2/PIR/LYAR/KLF10/THRA/RNF41/BCL6/BATF3/LILRB3/SMAD5/KITLG/SNX10/CEBPG/CIB1/FBXW7/STAT1/MYC/CEBPB/DPY30/CBFB/JAK2/NFE2/LDB1/IL15/BATF/TNF/PAF1/CD74/NFKBIA/MOV10/SH3PXD2A/TESC/LILRB1/TMOD3/KAT2B/TET2/HCLS1/FAM210B/EIF6/ZBTB7A/TGFB1/SIN3A/HIF1A/PTK2B/ROR2/SRF/ACTN1/OSCAR/LILRB4/TRAF6/TCIRG1/TLR4/NBEAL2/CEBPA/VEGFA/CDKN2B/CASP3/RELB/PAFAH1B1/CASP8/TMEM14C/VPS33A/GPR171/CDKN1C/KAT8/MITF/PML/ISG15/TNFRSF11A/CREB1/SIRT1/TYROBP/MFHAS1/TFE3/KLF13/ACVR1B/GAB3/G6PD/TAL1/OSTM1/ETS1/MYH9/IKZF1/RPS19/KMT2E/TMEM64/BATF2/MMP9/BMP4/HMGB2/PIK3CD/ID2/NME1/CNOT4/AGO1/SFXN1/INHBA/TNRC6B/TNRC6A/EVI2B/RAB7B/IREB2/DMTN/THOC5/ARNT/LEO1/PIAS3/DYRK3/NFE2L1/IRF8/FADD/SCIN/TFRC/ANXA2P2/PSEN1/DCSTAMP/LRRC17/EIF2AK1/ERCC2/SLC4A1/TREM2/IL25/C1QC/EPB42/IFNG/NR4A3/CLDN18/CSF3R/CD4/RB1/TLR3/INHA/IL12B/MEIS1/KMT2B/CSF1R/ANXA2/MTOR/PRTN3/PRKCQ/FOXP1/APP/GPR183/CDC73/SLC9B2/CCL19/EFNA2/TSPAN2/SLC25A38/ADAR/TIRAP/ZBTB16/TRIM58/CCR7/PRMT1/HOXA7/PRKCA/DNASE2/IL23A/WDR5/APCS/RASGRP4/FOXO3/THPO/CD109/MEF2C/L3MBTL1	187
BP	GO:0016049	cell growth	215/7096	484/18670	0.002017	0.01942	0.01448	IGF1/S100A9/S100A8/RTN4R/FN1/TRIM32/CDKN2D/CDKN1A/DPYSL2/MAD2L2/FBP1/PPP2CA/OSGIN1/WNT5A/C9orf72/SEMA4B/CHPT1/RASGRP2/ADNP2/SPP1/BCL6/RAB11A/PPARD/ADIPOR1/RPS6KA3/CIB1/ULK2/RGS2/LAMB2/ALCAM/VCL/AKAP13/SLC9A1/IFRD1/CISH/IGFBP7/APOE/GSK3B/ZEB2/PLAA/CXCL12/TMC8/SH3BP4/PSRC1/TWF2/TGFB1/PPP3CB/SIN3A/PAK1/MEGF8/IGFBP4/PTK2B/OSGIN2/BCL11A/ADAM15/SRF/HYAL2/NDUFS3/OGFR/SEMA4A/ITGA4/NET1/PARP2/RBBP7/VEGFA/USP9X/CDK5/TNFRSF12A/SFN/KLHL22/CYFIP2/ABL1/ENO1/PAFAH1B1/NDRG3/GDI1/PTCH2/MEX3C/LAMTOR1/SEMA4C/EBAG9/SDCBP/PML/SEMA4D/LRP1/SIRT1/CDKN2AIP/TMEM97/CTDP1/ACVR1B/DCC/G6PD/EIF4G2/CYFIP1/FLCN/DNPH1/DDX3X/WFDC1/SEMA6B/PDLIM5/SPHK1/ING1/PLXNA1/ARIH2/BTG1/NRP1/DISC1/SEMA3B/BCL2/DNM2/EI24/KDM2B/EXOSC2/L1CAM/NRP2/CDKN1B/CDKN2C/YY1/TSG101/LPAR3/IST1/FHL1/NDEL1/INHBA/OLFM1/CYBA/ST20/WDR36/SEMA5A/MMP14/FSTL4/DERL2/SERTAD2/IMPACT/CAMK2D/ULK1/EGFR/MUL1/SLC25A33/PPARA/ADAM17/CAV3/BIN3/ITSN2/SLIT2/ADIPOR2/DVL1/CPNE1/HAMP/TCHP/SEMA5B/DCSTAMP/SUPV3L1/CYP27B1/MAP2K4/TAF9B/LTBP4/EIF4G1/POU4F3/RASAL1/DCUN1D3/MAP3K13/RUFY3/EXOSC9/PLXNA3/SPOCK1/NAIF1/BAP1/FGFR1OP/HRG/SYT1/CPNE9/PIN1/HBEGF/BDKRB1/HSP90AB1/RB1/MAP2K5/SYT2/JADE1/MSX1/EIF2AK4/CDA/SYT4/PRKCZ/MTOR/PRKCQ/HPN/RHOA/AURKA/APP/RTN4/CDC73/CRABP2/RIMS2/LMX1A/FGF13/DCBLD2/SOCS2/CLSTN3/GJA1/IL17RB/KIAA1109/SESN2/WT1/KIF14/MACF1/PRSS2/TRPV2/KAZALD1/TRIM46/PTPRJ/PRDM11/BMPR2/SLIT3	215
BP	GO:0030968	endoplasmic reticulum unfolded protein response	62/7096	121/18670	0.002019	0.01942	0.01448	EXTL2/LMNA/TPP1/PTPN2/PPP1R15A/CREBRF/FKBP14/ATF4/EDEM1/TLN1/WFS1/SSR1/RNF175/HSPA5/NCK1/HERPUD2/TMEM33/PARP16/CREB3L2/SHC1/WIPI1/VAPB/PPP1R15B/CCND1/EIF2S1/GOSR2/CREB3L4/SERP1/PDIA6/KDELR3/BCL2L11/BAX/CTH/ASNS/DERL1/CREB3/ACADVL/DNAJB9/CANX/DERL2/STUB1/CALR/NFE2L2/EIF2AK2/YOD1/CTDSP2/HSP90B1/GFPT1/BFAR/TBL2/HYOU1/PPP2R5B/YIF1A/VCP/MBTPS2/ERN1/BAK1/MBTPS1/PREB/ARFGAP1/HDGF/ATF6B	62
BP	GO:0051250	negative regulation of lymphocyte activation	73/7096	146/18670	0.002023	0.01943	0.01448	PTPN6/LILRB2/ANXA1/LYN/IRF1/ARG2/GPNMB/MNDA/LST1/PTPN2/TNFRSF14/BCL6/SMAD7/TNFAIP3/BANK1/FGL2/IL4R/CEBPB/CBFB/HFE/CD74/TNFRSF21/LILRB1/DUSP3/AXL/TGFB1/SOCS5/HLA-F/IL20RB/PTPN22/ZBTB7B/SOCS6/DTX1/CASP3/IDO1/NFKBID/HMGB1/TYROBP/HLA-G/CTLA4/GLMN/ATM/TIGIT/VSIG4/SCGB1A1/PDCD1LG2/NRARP/BMP4/PARP3/ID2/LAG3/INHBA/CD300A/CD274/RHBDD3/LGALS9/LAX1/PGLYRP4/BTN2A2/HLX/TNFRSF13B/TNFSF4/MERTK/PAG1/SOCS1/HAVCR2/INHA/SLA2/MICA/CD80/TBX21/TYRO3/TWSG1	73
BP	GO:0031647	regulation of protein stability	132/7096	284/18670	0.002029	0.01943	0.01448	IGF1/USP3/CDKN1A/GRN/PINK1/CTSA/TNIP2/LMNA/TSC1/PIM1/CDC37L1/GAPDH/CHP1/HPS4/FLNA/SMAD7/ZBED3/SIAH1/FBXW7/FLOT1/WDR81/LAMP2/RNF139/RNF149/LAMP1/TESC/KRAS/CDC37/STXBP1/PFN1/CRTAP/GTPBP4/GNAQ/WFS1/PRKCD/USP28/CMTM6/BMP2/USP9X/CASP3/CCNH/APTX/NLK/CREB1/CLU/SIRT1/SAV1/TYROBP/CREBL2/CDKN2AIP/ATP1B2/IFT46/LRRK2/PPARGC1A/FLOT2/ZNF207/SUMO1/FBXL3/PTGES3/ATP1B3/USP4/TRIM24/TRIM21/BCL2/KDM8/ATP1B1/TMEM88/DERL1/GET4/ASGR2/PEX19/B4GALT5/CCT4/USP27X/NAPG/STUB1/FKBPL/CALR/FBXO4/NAA16/CCT8/MUL1/BAG2/USP7/DVL1/KAT2A/DPM3/MDM2/MAPK1/TELO2/STX12/APOA1/SH3GLB1/TAF9B/NCLN/CAPN3/OTUD3/SWSAP1/MTMR9/GNL3L/PIN1/HSP90AB1/RNF5/COG7/QRSL1/MSX1/TBL1X/ISOC2/PER3/TERT/NAA15/MCM8/TSPAN1/ZSWIM7/AURKA/RTN4/PIM2/CDC73/SNCA/SOX4/BAG5/PDCD10/USP19/TADA3/CHFR/PPIB/UBE2B/WNT10B/SMO/TARDBP/STXBP4/CSN3	132
BP	GO:0072593	reactive oxygen species metabolic process	132/7096	284/18670	0.002029	0.01943	0.01448	KLF4/NQO1/ITGAM/FPR2/KLF2/FYN/CX3CR1/TLR2/RAC2/ATP2B4/PDK4/ACP5/GCH1/CDKN1A/BST1/CLEC7A/PINK1/POR/SOD1/ARG2/STAT3/GNAI3/PTGS2/RNF41/PMAIP1/BIRC2/CYB5R4/JAK2/GSTP1/P2RX7/TNF/DDAH2/SH3PXD2A/MPV17/AKR1C3/PKD2/TICAM1/EIF6/TGFB1/CYP1B1/HIF1A/COQ7/CD36/ARF4/PTK2B/PRDX1/LEP/NCF4/PRKCD/INSR/HBB/PTX3/NCF2/NDUFS3/NCF1/MPV17L/TLR4/CAT/IL1B/AIF1/GPX3/RFK/CLU/TYROBP/BMP7/RAC1/GLA/PDGFB/NOXA1/LRRK2/G6PD/SPR/BCR/IMMP2L/AATF/CYP1A2/SIRT5/BCL2/DNM2/GNAI2/HDAC4/CD47/PRDX6/MMP3/GRB2/HBQ1/CYBA/CYBB/DDIT4/UCP1/VDAC1/AGXT2/NFE2L2/NDUFS1/BRCA1/DHFR/VAV1/EGFR/STK17A/SLC25A33/SESN1/PREX1/MAOB/PID1/PARL/RORA/IFNG/ATP7A/SLC7A2/HP/BCO2/CD34/HSP90AB1/DUOXA1/WDR35/GPX1/NDUFAF2/MTOR/RHOA/SNCA/ABCD1/SLC30A10/HBE1/ROCK2/CTNS/MPO/NNT/SESN2/RAB27A/TLR6/FOXO3/GCHFR	132
BP	GO:0018108	peptidyl-tyrosine phosphorylation	165/7096	363/18670	0.002042	0.01949	0.01453	IGF1/FYN/PTPN6/BST1/SOCS3/LYN/PPP2CA/PARP9/FCGR1A/ENPP2/CSK/ITGA5/FLT1/STAT3/PTPN2/HCK/LILRA5/TNFRSF14/NEDD9/BANK1/CD40/KITLG/MIF/MAP2K1/FBXW7/CD44/JAK2/PTPRC/IL15/DYRK4/ALK/DVL2/TNF/CD74/EPHB2/GPRC5B/ERCC6/DYRK2/PEAK1/HCLS1/AXL/LRP8/TGFB1/HGF/CBLB/SOCS5/CD36/ZFYVE28/PTK2B/LEP/PRKCD/ROR2/INSR/RAP2C/NRG1/ZGPAT/HYAL2/DYRK1B/NCF1/FLT3/PDGFC/FGR/IGF1R/VEGFA/EHD4/ABL1/PAK2/RAP2B/CSPG4/MVP/PTK6/CCL5/ARHGEF2/SHC1/SEMA4D/TESK2/IL7/SH3BP5L/TNFRSF18/IL6ST/TTBK1/ITK/IL6/LCK/PDGFB/EPHA8/SPINK1/TAL1/EPHA10/PTK2/SNX6/HDAC2/NRP1/TMEM102/TYK2/CLCF1/TSG101/ROR1/TEC/OSM/MAP2K2/CD300A/INPP5F/PDGFA/FER/FRK/DMTN/HES1/VPS25/DYRK3/CNTF/EIF2AK2/EGFR/CNOT7/IL18/ADAM17/ABL2/PSEN1/MERTK/SOCS1/MAP2K4/WEE1/TREM2/IL3/TSLP/MATK/EPHB1/LMTK2/IFNG/JAK1/FGFR1OP/HRG/TNFSF18/RET/TXK/HBEGF/CD4/LACRT/MAP2K5/PPP2R5B/IL12B/PRKCZ/RELN/CD80/CSF1R/MTOR/CLK1/TYRO3/APP/MET/ARL2BP/LRP4/GHR/CD3E/STK16/GREM1/CD24/ERBB3/IL23A/CNTN1/PDGFD/GHRL/NTRK2/PTPRJ/MIR146A	165
BP	GO:0006672	ceramide metabolic process	49/7096	92/18670	0.002044	0.01949	0.01453	ASAH1/HEXB/SGMS2/PPP2CA/GM2A/CERS2/PSAP/P2RX7/DEGS1/TNF/FUT7/CLN8/SGPL1/GALC/PRKCD/B4GALT6/CERS5/HTRA2/SPTLC2/SAMD8/PLA2G15/CLN3/GLA/CERS4/ALDH5A1/ORMDL2/SPHK1/P2RX1/ORMDL3/SGMS1/B4GALNT1/NAGA/CLN6/FUT6/B4GALT5/UGCG/ST8SIA4/AGK/ACER3/PRKAA1/PLA2G6/CERK/NEU1/ST6GALNAC3/SMPD1/ST6GALNAC6/SMPD2/ST3GAL5/DEGS2	49
BP	GO:0019319	hexose biosynthetic process	49/7096	92/18670	0.002044	0.01949	0.01453	FBP1/PGK1/MDH1/AKR1B1/PTPN2/GAPDH/SIK1/PER2/SLC37A4/KAT2B/PGAM1/ATF4/PDK2/TPI1/PCK2/LEP/ALDOC/DDB1/ENO1/ALDOA/SLC25A10/SLC35B4/CRTC2/SIRT1/GPI/DGAT2/PPARGC1A/NLN/SLC25A12/PFKFB1/FOXK2/SORD/GOT2/PGK2/SERPINA12/MST1/PPARA/SLC25A13/KAT2A/ENO2/OGT/PC/GCG/SESN2/RBP4/C1QTNF3/WDR5/G6PC/FAM3A	49
BP	GO:0051260	protein homooligomerization	160/7096	351/18670	0.002048	0.01949	0.01453	PKD2L1/VASP/BMF/ACOT13/DPYSL3/GCH1/ALOX5AP/APPL2/BCL10/SKI/FBP1/KCTD15/CBR4/GBP1/MCOLN1/JMJD6/DISP1/SYT11/ALDH9A1/PFKM/PFKP/STEAP4/RHOC/MIF/ACPP/FLOT1/G3BP2/LNX2/KCNC4/HMOX1/KCTD17/PCBD1/AQP11/KCTD9/GBP5/PKD2/APOE/KCNA3/PKM/CHMP4B/EVL/ALAD/DGKD/FIS1/APIP/KCTD10/MARCKS/ATL1/TMCC1/KCTD1/CBY1/ZBTB1/HTRA2/RYR1/DECR1/HSF4/GOPC/AKR1C1/EHD4/CAT/ALDOA/CD3D/SAMHD1/GPX3/TK1/ACACB/EHD1/SHKBP1/TRMT61B/CRTC2/CLU/SMARCAD1/CLPP/TRPM4/TRPM2/HLA-G/TOR1B/RNF213/ITLN1/ALDH5A1/ARC/CRTC1/CRTC3/TOR1A/SHMT2/PAM/BCL2L11/P2RX1/MGST1/RXRA/RAD52/NACC2/USP16/ANXA6/ATL3/TGM2/BAX/CD247/CHMP2A/HSD17B10/HINT3/FUS/CTH/KCTD11/DERL1/TYSND1/CD3G/MLKL/PPAT/CPT1A/OSBPL2/MICU1/VWF/GLS/IKZF4/KCNA2/DNM1L/FGFRL1/SHMT1/PEX14/PEX11B/CEP57/TRAF2/PRF1/LETM1/CLYBL/RIOK3/TIFA/SRR/KCNS2/SYT1/EHD3/GJA8/KCNA4/ATXN10/DYNC1LI2/KCTD3/KCND1/CDA/DCTPP1/VCP/KCTD5/PCBD2/B4GALT1/IAPP/P2RX2/ST13/CRYZ/SIGMAR1/PNPT1/HCN1/KCTD18/PRMT1/CD3E/PFKL/TDO2/MAT1A/KCTD16/KCTD21/SCUBE3	160
BP	GO:1903531	negative regulation of secretion by cell	101/7096	211/18670	0.002091	0.01987	0.01481	CRHBP/CCR2/FN1/EZR/PTGER4/IL27RA/ANXA1/IL1R2/RHBDF2/GBP1/ARG2/RAP1B/SYT11/ERP29/TMBIM6/DPH3/LILRA5/NLRP3/HADH/TNFAIP3/BANK1/SIRT4/LGR4/ENY2/NLRP12/RGCC/FAM3D/TNF/HMOX1/TNFRSF21/APOE/HMGCR/LILRB1/CD22/PIM3/ENHO/LEP/PNKD/SERPINB1/HLA-F/MAPKBP1/PTPN22/ABR/VAMP3/RSAD2/IL1B/RAP1A/PML/P2RY12/RAB33B/KALRN/CD200R1/KLF7/IDH2/BCR/GNAI2/NR1H3/FFAR4/SYTL4/OSM/INHBA/CD300A/LGALS9/VPS4B/RABGEF1/BTN2A2/CPTP/F2R/PPP1R11/NMB/MAOB/TLR8/FMR1/SRGN/IL13RA2/APOA1/TNFRSF4/FRMD4A/CD84/NPVF/CD34/IL1RAPL1/INHA/STXBP3/SYT4/NDUFAF2/MAP4K4/C5AR2/SNCA/CX3CL1/FOXF1/PFKL/FGF23/NR1H4/TLR6/PSMD9/C1QTNF3/P2RY1/TACR2/GHRL/RHBDF1	101
BP	GO:0071349	cellular response to interleukin-12	29/7096	49/18670	0.002107	0.01999	0.01491	SERPINB2/TALDO1/LMNB1/SOD1/RAP1B/MIF/PITPNA/JAK2/HNRNPA2B1/PAK2/GSTO1/CAPZA1/SNRPA1/ARF1/MTAP/CNN2/LCP1/CD47/TYK2/CFL1/IL12RB1/PLCB1/MSN/IFNG/JAK1/IL12B/ANXA2/PDCD4/AIP	29
BP	GO:0046545	development of primary female sexual characteristics	53/7096	101/18670	0.00212	0.02007	0.01496	SOD1/RETN/PLEKHA1/KITLG/LFNG/CEBPB/NUPR1/UBE3A/ARRB1/CTNNA1/SGPL1/ZNF830/LEP/INSR/PTX3/EIF2B5/HSPA5/VEGFA/CASP3/IDH1/SIRT1/ACVR1B/ATM/IMMP2L/BCL2/BAX/TIPARP/CASP2/NUP107/INHBA/HYAL3/MMP14/FZD4/SLIT2/CCDC182/FANCG/TAF4/LHFPL2/FSHR/INHA/KMT2B/FANCA/ZFP42/EIF2B2/NRIP1/BMPR1B/ADCYAP1R1/AMHR2/MMP19/WT1/FOXO3/LHX9/SLIT3	53
BP	GO:0006754	ATP biosynthetic process	79/7096	160/18670	0.002132	0.02007	0.01496	IGF1/CBFA2T3/HK3/LDHA/PINK1/FBP1/PGK1/VPS9D1/STAT3/PFKFB3/NUP62/NUP160/PFKM/PFKP/GAPDH/NUP214/SLC2A6/P2RX7/NUPR1/PGAM1/PKM/GALK1/EIF6/TPI1/ZBTB7A/TGFB1/NUP85/HIF1A/SEH1L/INSR/ALDOC/NUP43/ENO1/DNAJC30/ALDOA/POM121/OGDH/GPI/PFKFB4/PPARGC1A/FLCN/DHTKD1/SLC25A12/LDHC/PRKAG2/MYOG/NCOR1/PFKFB1/NUP88/HDAC4/NUP107/FOXK2/DDIT4/PGK2/PFKFB2/ARNT/PPARA/NUP93/SLC25A13/PRKAA1/PSEN1/NUP205/ENO2/PID1/SLC4A1/TREM2/NUP50/IFNG/PRKAG1/OGT/ESRRB/ZBTB20/VCP/ADPGK/TAZ/APP/PFKL/POM121C/AAAS	79
BP	GO:0010769	regulation of cell morphogenesis involved in differentiation	139/7096	301/18670	0.002136	0.02007	0.01496	MYADM/S100A10/RTN4R/FN1/SIPA1L1/DPYSL2/SKIL/DNM3/WNT5A/GBP1/SEMA4B/SPP1/RAB11A/NEDD9/FLNA/MAP2K1/CIB1/ULK2/ACTN4/YWHAH/EPHB2/ARHGDIA/IFRD1/APOE/GSK3B/ZEB2/ZSWIM6/ACTR2/CXCL12/PTPRO/PLXNB2/LRP8/UBE3A/TWF2/SIN3A/PAK1/RAPGEF2/MEGF8/SS18L2/PLXNC1/SRF/BAIAP2/SEMA4A/VEGFA/CDK5/TNFRSF12A/TRAK2/ABL1/PAFAH1B1/GDI1/SEMA4C/SEMA4D/ANKRD27/LRP1/CRK/RAC1/CAPRIN1/KALRN/LRRK2/DCC/CYFIP1/MYCBP2/DOCK5/ARC/PTK2/SEMA6B/PDLIM5/PLXNA1/NRP1/DISC1/SEMA3B/PLXND1/DNM2/NEDD4/L1CAM/MARK2/UNC13D/CFL1/LPAR3/KANK1/TRIOBP/IST1/NDEL1/SYNGAP1/DAB1/OLFM1/WDR36/SEMA5A/DMTN/FSTL4/BHLHB9/CORO1C/DNM1L/CALR/NSMF/C1QBP/AMIGO1/RCC2/SS18L1/PREX1/SLIT2/PSEN1/FMR1/SEMA5B/CHRNB2/SHOX2/APOA1/MAP3K13/RUFY3/PLXNA3/RET/TRAK1/IL1RAPL1/KNDC1/TACSTD2/PLXNA2/ARPC2/NR2E1/RELN/CHODL/RHOA/BRSK1/LIMS1/RTN4/ITGB1BP1/PARP6/CRABP2/FGF13/LRP4/WNT7A/LZTS1/SHANK3/KEL/MACF1/TRPV2/NTRK2/TRIM46/CAMK2B/BMPR2	139
BP	GO:0032401	establishment of melanosome localization	16/7096	23/18670	0.002136	0.02007	0.01496	BBS5/RAB11A/MLPH/MYO5A/ASIP/BLOC1S6/BBS2/MKKS/BBS4/BLOC1S3/DCTN2/BBS7/GPR143/MREG/CDH3/RAB27A	16
BP	GO:0032703	negative regulation of interleukin-2 production	16/7096	23/18670	0.002136	0.02007	0.01496	EZR/ZFP36/GBP1/TNFAIP3/PTPRC/IL20RB/HOMER3/VSIG4/KAT5/HDAC7/LAG3/HAVCR2/CD34/TBX21/NAV3/NR1H4	16
BP	GO:0034123	positive regulation of toll-like receptor signaling pathway	16/7096	23/18670	0.002136	0.02007	0.01496	TLR1/TLR2/FLOT1/TLR5/PTPN22/RSAD2/HMGB1/MFHAS1/TREML4/NR1H3/WDFY1/CYBA/TLR3/LBP/RTN4/TIRAP	16
BP	GO:0051904	pigment granule transport	16/7096	23/18670	0.002136	0.02007	0.01496	BBS5/RAB11A/MLPH/MYO5A/ASIP/BLOC1S6/BBS2/MKKS/BBS4/BLOC1S3/DCTN2/BBS7/GPR143/MREG/CDH3/RAB27A	16
BP	GO:0031669	cellular response to nutrient levels	112/7096	237/18670	0.002153	0.02017	0.01503	VDR/FYN/USF2/NAMPT/PDK4/UPP1/CDKN1A/ATG7/AIFM1/TSC1/SOD1/SRD5A1/PIM1/KLF10/PTGS2/PMAIP1/GAS2L1/SIK1/ATG14/FOLR2/LAMP2/GDAP1/IL15/FAS/P2RX7/HFE/HMOX1/AKR1C3/ATF4/PDK2/WDR24/HIGD1A/XPR1/MAP1LC3A/SEH1L/LEP/BCL11A/SRF/BAIAP2/HSPA5/HNRNPA1/CDKN2B/PPM1D/SIK2/RRAGD/P2RY12/WIPI1/NPRL3/SIRT1/TRPM4/EIF2S1/KPTN/LRRK2/MAP1LC3C/NMRAL1/FNIP1/ZFYVE1/TRIM24/MYBBP1A/MAPK8/BCL2/ASNS/WDR45B/CTSV/CYBA/CYBB/TNRC6A/SREBF2/MAP3K5/RRAGA/DNM1L/NFE2L2/IMPACT/EIF2AK2/ULK1/DSC2/ITFG2/AMIGO1/SESN1/HSP90B1/AQP3/PRKAA1/DNAJC15/MDM2/MAPK1/MTMR3/P2RY4/SH3GLB1/CYP27B1/NPRL2/EIF4G1/DAP/TBL2/DAPL1/GABARAPL1/CLEC16A/CACNB3/WNT2B/EIF2AK4/CADPS2/MTOR/PICK1/DEPDC5/CIB2/SSH1/FGF23/NR1H4/SESN2/UCN3/P2RY1/ALB/BMPR2	112
BP	GO:0032872	regulation of stress-activated MAPK cascade	112/7096	237/18670	0.002153	0.02017	0.01503	NOD2/EZR/DUSP1/PINK1/WNT5A/ZNF622/SH3RF1/DUSP10/MAP2K1/MYC/GSTP1/FAS/DVL2/TNF/ERCC6/ZEB2/MAP3K4/HMGCR/SLAMF1/DUSP3/TAOK3/GADD45B/HGF/PAK1/MAP4K5/PTK2B/PRDX1/LEP/ROR2/TRAF6/NCF1/TLR4/PTPN22/TPD52L1/BMP2/IGF1R/VEGFA/HRAS/PAFAH1B1/IL1B/DTNBP1/SEMA4C/AGER/MAP3K12/RASGRP1/SDCBP/MDFIC/HMGB1/TNFRSF11A/IL1RN/MFHAS1/DUSP19/MAP4K2/CYLD/RELL2/SPHK1/NCOR1/EDAR/MAP3K6/MAP4K1/ZMYND11/MLKL/MAP2K2/MAP3K11/SH3RF3/FZD5/AMBP/BIRC7/MAP3K5/PLCB1/EIF2AK2/EGFR/MUL1/CAV3/TRAF2/FZD4/MAPK1/MAP2K4/MAP3K13/PPEF2/IGBP1/EPHB1/HIPK3/DNAJA1/ANKRD6/ULK4/TLR3/FZD7/MEN1/MAP4K4/TRPV4/APP/ERN1/PDCD4/PDCD10/CCL19/TIRAP/NBR1/TRAF4/AIDA/WNT7A/CCR7/PRMT1/IL26/DAXX/SERPINF2/TLR6/FZD10/NRK/SASH1/IL37/MAP3K9	112
BP	GO:0006403	RNA localization	109/7096	230/18670	0.002178	0.02037	0.01519	ZFP36/TSC1/NXF1/SRSF5/NUP62/NUP160/CHTOP/NUP214/FLOT1/ENY2/G3BP2/AGFG1/KHDRBS1/RAN/ALYREF/RNPS1/EIF6/MX2/MAGOHB/SARNP/NUP85/NXT1/CETN3/SEH1L/SIDT1/RUVBL2/RUVBL1/YTHDC1/BICD2/NAF1/NUP43/HNRNPA1/NPM1/HNRNPA2B1/PURA/RBM8A/MVP/SNUPN/FYTTD1/DDX19B/DHX9/U2AF1/DCP2/POM121/ZNF593/SRSF3/SYMPK/XPOT/SFPQ/CPSF3/MYO1C/ATXN2/ARC/BICD1/ATM/FBL/RBM27/TST/NHP2/FIP1L1/EXOSC2/NUP88/THOC2/YY1/SRSF6/SRSF7/CKAP5/NUP107/CDC40/CCT4/NPIPA1/THOC5/POLR2D/TOMM20/NXT2/CCT8/U2AF1L4/EIF5A/NUP93/ATR/CETN2/LTV1/THOC6/RIOK2/SSB/SRRM1/NUP205/FMR1/PHAX/SRSF4/EIF4E/NUP50/PARP11/EXOSC3/DHX38/MCM3AP/PCID2/HNRNPA3/CPSF2/CPSF1/PNPT1/SIDT2/ZNHIT6/NOP10/RRS1/POM121C/AAAS/UPF1/RFTN1	109
BP	GO:0035722	interleukin-12-mediated signaling pathway	28/7096	47/18670	0.002181	0.02037	0.01519	SERPINB2/TALDO1/LMNB1/SOD1/RAP1B/MIF/PITPNA/JAK2/HNRNPA2B1/PAK2/GSTO1/CAPZA1/SNRPA1/ARF1/MTAP/CNN2/LCP1/TYK2/CFL1/IL12RB1/PLCB1/MSN/IFNG/JAK1/IL12B/ANXA2/PDCD4/AIP	28
BP	GO:0018212	peptidyl-tyrosine modification	166/7096	366/18670	0.002218	0.02069	0.01542	IGF1/FYN/PTPN6/BST1/SOCS3/LYN/PPP2CA/PARP9/FCGR1A/ENPP2/CSK/ITGA5/FLT1/STAT3/PTPN2/HCK/LILRA5/TNFRSF14/NEDD9/BANK1/CD40/KITLG/MIF/MAP2K1/FBXW7/CD44/JAK2/PTPRC/IL15/DYRK4/ALK/DVL2/TNF/CD74/EPHB2/GPRC5B/ERCC6/DYRK2/PEAK1/HCLS1/AXL/LRP8/TGFB1/HGF/CBLB/SOCS5/CD36/ZFYVE28/PTK2B/LEP/PRKCD/ROR2/INSR/RAP2C/NRG1/ZGPAT/HYAL2/DYRK1B/NCF1/FLT3/PDGFC/FGR/IGF1R/VEGFA/EHD4/TPST2/ABL1/PAK2/RAP2B/CSPG4/MVP/PTK6/CCL5/ARHGEF2/SHC1/SEMA4D/TESK2/IL7/SH3BP5L/TNFRSF18/IL6ST/TTBK1/ITK/IL6/LCK/PDGFB/EPHA8/SPINK1/TAL1/EPHA10/PTK2/SNX6/HDAC2/NRP1/TMEM102/TYK2/CLCF1/TSG101/ROR1/TEC/OSM/MAP2K2/CD300A/INPP5F/PDGFA/FER/FRK/DMTN/HES1/VPS25/DYRK3/CNTF/EIF2AK2/EGFR/CNOT7/IL18/ADAM17/ABL2/PSEN1/MERTK/SOCS1/MAP2K4/WEE1/TREM2/IL3/TSLP/MATK/EPHB1/LMTK2/IFNG/JAK1/FGFR1OP/HRG/TNFSF18/RET/TXK/HBEGF/CD4/LACRT/MAP2K5/PPP2R5B/IL12B/PRKCZ/RELN/CD80/CSF1R/MTOR/CLK1/TYRO3/APP/MET/ARL2BP/LRP4/GHR/CD3E/STK16/GREM1/CD24/ERBB3/IL23A/CNTN1/PDGFD/GHRL/NTRK2/PTPRJ/MIR146A	166
BP	GO:1903322	positive regulation of protein modification by small protein conjugation or removal	68/7096	135/18670	0.002228	0.02075	0.01547	NOD2/BCL10/PINK1/SMAD7/ARRDC4/BIRC2/FBXW7/RNF111/UBE2N/SKP2/DCUN1D1/TICAM1/NMI/UBE3A/ARRDC3/ARRB1/WFS1/UBE2S/RASSF5/PTTG1IP/TRAF6/PTPN22/HSPA5/CDK9/LRRK2/MYCBP2/HSPBP1/SPHK1/PHF23/DCUN1D5/AIMP2/TNIP1/HDAC4/BIRC3/TOLLIP/ADRB2/DERL1/TSPYL5/TBC1D7/PEF1/KLHL40/UBE2C/BIRC7/ARNT/STUB1/RNF20/PIAS3/FBXO4/COMMD1/BRCA1/MUL1/FANCM/DCUN1D3/CDC20/UBE2I/MASTL/PIN1/DCUN1D4/VCP/TOPORS/MALT1/XIAP/PAXIP1/CHFR/GNL3/RASD2/AVPR2/MAPK9	68
BP	GO:0006575	cellular modified amino acid metabolic process	97/7096	202/18670	0.002236	0.02078	0.01549	SLC27A1/SLC22A4/PLA2G12A/GCH1/GCLM/POR/SOD1/MTHFD2/ALDH9A1/PLSCR1/PCYOX1/PANK2/AHCY/ABHD12/ALDH7A1/FOLR2/PTDSS2/MGST2/GSTP1/SLC7A11/MBOAT1/GSR/GGCT/CPQ/CRTAP/APIP/PLA1A/ACADM/SERINC1/EGLN1/ETHE1/PAX8/MTRR/GCLC/ENOPH1/GSTZ1/GATM/GSTA1/HAGH/IDH1/ALDH4A1/GPX4/PCYOX1L/GSTM3/G6PD/PLOD1/EGLN3/ALDH5A1/PDZD11/SHMT2/VNN1/MGST1/SERINC3/MMACHC/ATIC/GSTM5/BHMT/PLOD2/GSS/CNDP2/GAMT/SLC46A1/CPT1A/TYMS/SLC5A6/HPGDS/GSTM4/GOT2/AHCYL2/NFE2L2/NFE2L1/SHMT1/AHCYL1/DHFR/AASDHPPT/GGT7/GGT5/FPGS/DUOXA1/SULT1B1/ALDH1L1/CHAC2/CROT/GPX1/HPN/SLC25A32/ABHD16A/CHDH/GGTLC1/DIO2/VNN3/CTNS/SERINC2/P4HA1/CKMT2/PIPOX/LPCAT3	97
BP	GO:2000377	regulation of reactive oxygen species metabolic process	94/7096	195/18670	0.002237	0.02078	0.01549	KLF4/ITGAM/FPR2/KLF2/FYN/CX3CR1/RAC2/ATP2B4/ACP5/GCH1/CDKN1A/BST1/CLEC7A/PINK1/SOD1/ARG2/STAT3/GNAI3/PTGS2/RNF41/BIRC2/JAK2/GSTP1/TNF/DDAH2/MPV17/AKR1C3/PKD2/TICAM1/EIF6/TGFB1/CYP1B1/HIF1A/COQ7/CD36/ARF4/PTK2B/LEP/PRKCD/INSR/HBB/PTX3/MPV17L/TLR4/IL1B/AIF1/CLU/TYROBP/BMP7/RAC1/GLA/PDGFB/NOXA1/G6PD/BCR/AATF/SIRT5/BCL2/DNM2/GNAI2/HDAC4/CD47/MMP3/GRB2/CYBA/UCP1/VDAC1/AGXT2/NFE2L2/BRCA1/DHFR/EGFR/STK17A/SLC25A33/PID1/PARL/IFNG/HP/BCO2/CD34/HSP90AB1/DUOXA1/WDR35/MTOR/RHOA/SNCA/ABCD1/SLC30A10/ROCK2/CTNS/NNT/RAB27A/TLR6/FOXO3	94
BP	GO:0031346	positive regulation of cell projection organization	173/7096	383/18670	0.002255	0.02091	0.01559	S100A9/CDC42EP4/FN1/FYN/RAC2/DPYSL3/SKIL/GRN/LYN/DNM3/ENPP2/WNT5A/ARAP1/RAB11A/CAMK1D/MAP2K1/RGS2/P2RX7/ALK/DVL2/EZH2/ARHGDIA/KCTD17/APOE/ZEB2/ACTR2/PLAA/CXCL12/PLXNB2/LRP8/TWF2/PLEK2/PFN1/ARSB/CDC42EP2/HGF/PAK1/RAPGEF2/MEGF8/SS18L2/PTK2B/PLXNC1/SRF/SCN1B/BAIAP2/FUZ/ITSN1/HSPA5/NCK1/FIG4/VEGFA/TNFRSF12A/HRAS/PAFAH1B1/GDI1/GRIP1/FAM98A/CREB3L2/FBXO38/PTK6/RAP1A/SEMA4D/P2RY12/ANKRD27/LRP1/NPTN/BMP7/TMEM106B/RAC1/PLEKHM1/CAPRIN1/CCDC88A/KALRN/CDC42EP3/CYFIP1/CRTC1/CORO1B/BBS4/ARF1/SETX/PLXNA1/BMP5/NRP1/DISC1/PLXND1/DNM2/AVIL/L1CAM/BCAS3/HDAC4/MARK2/RHOQ/NME1/LPAR3/IST1/ITGA2/NDEL1/MOB2/SHANK1/CPEB3/SEMA5A/ITGA3/LPAR1/BHLHB9/CORO1C/DNM1L/AP2A1/FZD1/NFE2L2/CNTF/RAB8B/MUL1/AMIGO1/ABL2/SS18L1/DOCK11/FZD4/ITSN2/SLIT2/LRRC7/FSCN1/DVL1/WNT1/KAT2A/PSEN1/FMR1/GPC2/SHOX2/KATNB1/RASAL1/TGFB3/MAP3K13/RUFY3/PLXNA3/ATP7A/SYT1/RET/TRAK1/CPNE9/TMEM30A/MIEN1/IL1RAPL1/PPP2R5B/PLXNA2/SYT2/ARPC2/SYT4/RELN/EPS8L2/CEP120/MTOR/CHODL/NAV3/RHOA/C21orf91/CX3CL1/CCL19/PARP6/CRABP2/RIMS2/CCR7/SHANK3/TENM2/RP1/NCKAP1/MACF1/CNTN1/WRAP73/TRPV2/ZMYND8/NTRK2/CAMK2B/BMPR2	173
BP	GO:0002335	mature B cell differentiation	17/7096	25/18670	0.002277	0.02093	0.01561	DLL1/NOTCH2/LFNG/DOCK10/POU2F2/PTK2B/PLCG2/ITM2A/LGALS1/ADA/ITFG2/DOCK11/CDH17/PLCL2/GPR183/MALT1/SLAMF8	17
BP	GO:0002507	tolerance induction	17/7096	25/18670	0.002277	0.02093	0.01561	LILRB2/LYN/TNFAIP3/IRAK3/TGFB1/CLC/HLA-E/IDO1/HMGB1/HLA-G/CCR4/CD274/LGALS9/ICOS/HAVCR2/CD3E/PDCD1	17
BP	GO:0032400	melanosome localization	17/7096	25/18670	0.002277	0.02093	0.01561	BBS5/RAB11A/MLPH/MYO5A/ASIP/VPS33A/BLOC1S6/BBS2/MKKS/BBS4/BLOC1S3/DCTN2/BBS7/GPR143/MREG/CDH3/RAB27A	17
BP	GO:0060330	regulation of response to interferon-gamma	17/7096	25/18670	0.002277	0.02093	0.01561	SOCS3/PARP9/PTPN2/NLRC5/STAT1/JAK2/IFNGR2/CDC37/NR1H2/SUMO1/NR1H3/IFNGR1/SOCS1/IFNG/JAK1/TXK/HSP90AB1	17
BP	GO:0060334	regulation of interferon-gamma-mediated signaling pathway	17/7096	25/18670	0.002277	0.02093	0.01561	SOCS3/PARP9/PTPN2/NLRC5/STAT1/JAK2/IFNGR2/CDC37/NR1H2/SUMO1/NR1H3/IFNGR1/SOCS1/IFNG/JAK1/TXK/HSP90AB1	17
BP	GO:1903306	negative regulation of regulated secretory pathway	17/7096	25/18670	0.002277	0.02093	0.01561	CCR2/RAP1B/HMOX1/HLA-F/ABR/RAP1A/BCR/GNAI2/CD300A/LGALS9/RABGEF1/FMR1/IL13RA2/CD84/STXBP3/SYT4/FOXF1	17
BP	GO:0009062	fatty acid catabolic process	56/7096	108/18670	0.002301	0.02113	0.01575	ALDH3A2/HADHB/PPARD/HADH/ACAA1/PHYH/SCP2/ETFA/CPT2/AUH/ABCD3/PCK2/LEP/ECH1/ACADM/ACADS/DECR1/MCEE/AIG1/PLA2G15/ACOX1/ETFDH/ECI2/SLC27A2/HSD17B4/ACACB/ACOX2/ACBD5/IRS2/BDH2/ABHD3/DECR2/MLYCD/PCCB/ECI1/NUDT19/ETFB/PEX13/TYSND1/CPT1A/EHHADH/ACADVL/HADHA/NUDT7/PPARA/ACAA2/ACOX3/CROT/MTOR/CYP4F3/ABCD1/ABHD16A/HACL1/SESN2/HAO1/ACOT8	56
BP	GO:0043506	regulation of JUN kinase activity	47/7096	88/18670	0.002317	0.02119	0.0158	WNT5A/DUSP10/GSTP1/DVL2/TNF/ERCC6/ZEB2/MAP3K4/TAOK3/PAK1/MAP4K5/PTK2B/ROR2/TRAF6/PTPN22/DTNBP1/AGER/MAP3K12/MDFIC/TNFRSF11A/DUSP19/MAP4K2/MAP3K6/MAP4K1/MLKL/MAP3K11/FZD5/BIRC7/MAP3K5/MUL1/TRAF2/FZD4/MAP2K4/MAP3K13/PPEF2/HIPK3/DNAJA1/ERN1/PDCD4/CCL19/AIDA/DAXX/TLR6/FZD10/NRK/SASH1/MAP3K9	47
BP	GO:0034198	cellular response to amino acid starvation	26/7096	43/18670	0.002318	0.02119	0.0158	CDKN1A/FAS/ATF4/WDR24/MAP1LC3A/SEH1L/RRAGD/NPRL3/EIF2S1/KPTN/MAPK8/MAP3K5/RRAGA/IMPACT/EIF2AK2/ITFG2/SESN1/MAPK1/SH3GLB1/NPRL2/DAP/DAPL1/EIF2AK4/MTOR/DEPDC5/SESN2	26
BP	GO:1901658	glycosyl compound catabolic process	26/7096	43/18670	0.002318	0.02119	0.0158	FUCA1/TYMP/PNP/UPP1/AHCY/HDDC3/NT5C/CDADC1/DPYD/APOBEC3G/GLA/APOBEC3C/GUSB/APOBEC2/DERA/NAGA/ADA/APOBEC3B/FUCA2/CDA/NT5C3A/ENPP4/NT5M/UPP2/ADAL/ABHD10	26
BP	GO:0009145	purine nucleoside triphosphate biosynthetic process	84/7096	172/18670	0.002349	0.02144	0.01598	IGF1/CBFA2T3/HK3/LDHA/PINK1/FBP1/PGK1/VPS9D1/STAT3/PFKFB3/NUP62/NUP160/PFKM/PFKP/GAPDH/NUP214/SLC2A6/P2RX7/NUPR1/PGAM1/PKM/GALK1/EIF6/TPI1/ZBTB7A/TGFB1/NUP85/HIF1A/SEH1L/ADK/INSR/ALDOC/NUP43/IMPDH1/ENO1/DNAJC30/ALDOA/POM121/OGDH/GPI/PFKFB4/PPARGC1A/FLCN/DHTKD1/NME3/SLC25A12/LDHC/NME4/PRKAG2/MYOG/NCOR1/PFKFB1/NUP88/HDAC4/NME1/NUP107/FOXK2/DDIT4/PGK2/PFKFB2/ARNT/PPARA/NUP93/SLC25A13/PRKAA1/PSEN1/NUP205/ENO2/PID1/SLC4A1/TREM2/NUP50/IFNG/PRKAG1/OGT/ESRRB/ZBTB20/VCP/ADPGK/TAZ/APP/PFKL/POM121C/AAAS	84
BP	GO:0006611	protein export from nucleus	87/7096	179/18670	0.00237	0.02158	0.01609	TSC1/NXF1/SRSF5/BARD1/NUP62/NUP160/CHP1/STRADB/CHTOP/NUP214/ENY2/AGFG1/RAN/GSK3B/ALYREF/RNPS1/EIF6/MAGOHB/TGFB1/SARNP/NUP85/NXT1/SEH1L/YTHDC1/NUP43/IFI27/CDK5/SFN/NPM1/SP100/HNRNPA2B1/EMD/IL1B/RBM8A/FYTTD1/DDX19B/U2AF1/POM121/ZNF593/SRSF3/SYMPK/XPOT/EGR2/CCHCR1/CPSF3/FIP1L1/NUP88/THOC2/SRSF6/SRSF7/PRKACA/CSE1L/NUP107/CDC40/THOC5/POLR2D/CALR/AHCYL1/U2AF1L4/TXN/EIF5A/NUP93/LTV1/THOC6/RIOK2/SSB/SRRM1/NUP205/MDM2/TCF7L2/YWHAE/ANKLE1/SRSF4/EIF4E/NUP50/DHX38/MCM3AP/PCID2/CPSF2/CPSF1/STRADA/XPO4/RRS1/POM121C/AAAS/CTDSPL2/UPF1	87
BP	GO:0002825	regulation of T-helper 1 type immune response	18/7096	27/18670	0.002378	0.02158	0.01609	CCR2/IL27RA/ANXA1/SLC11A1/IL4R/IL18R1/SOCS5/IL1B/IL1R1/IL12RB1/HLX/IL18/TNFSF4/HAVCR2/IL12B/CD80/CCL19/IL23A	18
BP	GO:0006884	cell volume homeostasis	18/7096	27/18670	0.002378	0.02158	0.01609	KCNN4/P2RX7/SCTR/CLCN3/SLC12A9/GNB3/SLC12A2/SLC12A8/E2F4/LRRC8A/CLNS1A/SLC12A1/SLC12A7/KCNMA1/TRPV4/SLC12A4/SHANK3/SLC12A6	18
BP	GO:0039528	cytoplasmic pattern recognition receptor signaling pathway in response to virus	18/7096	27/18670	0.002378	0.02158	0.01609	IRF7/BIRC2/DDX60/DDX58/LSM14A/PUM2/NPLOC4/IFIH1/SEC14L1/ANKRD17/BIRC3/C1QBP/GPATCH3/RIOK3/TRIM15/NLRX1/TSPAN6/ZCCHC3	18
BP	GO:0050657	nucleic acid transport	93/7096	193/18670	0.002387	0.02158	0.01609	ZFP36/TSC1/NXF1/SRSF5/NUP62/NUP160/CHTOP/NUP214/FLOT1/ENY2/G3BP2/AGFG1/KHDRBS1/RAN/ALYREF/RNPS1/EIF6/MX2/MAGOHB/SARNP/NUP85/NXT1/CETN3/SEH1L/SIDT1/YTHDC1/BICD2/NUP43/HNRNPA1/NPM1/HNRNPA2B1/PURA/RBM8A/MVP/SNUPN/FYTTD1/DDX19B/DHX9/U2AF1/POM121/ZNF593/SRSF3/SYMPK/XPOT/SFPQ/CPSF3/MYO1C/ATXN2/ARC/RBM27/TST/FIP1L1/NUP88/THOC2/SRSF6/SRSF7/CKAP5/NUP107/CDC40/NPIPA1/THOC5/POLR2D/TOMM20/NXT2/U2AF1L4/EIF5A/NUP93/CETN2/LTV1/THOC6/RIOK2/SSB/SRRM1/NUP205/FMR1/PHAX/SRSF4/EIF4E/NUP50/PARP11/DHX38/MCM3AP/PCID2/HNRNPA3/CPSF2/CPSF1/PNPT1/SIDT2/RRS1/POM121C/AAAS/UPF1/RFTN1	93
BP	GO:0050658	RNA transport	93/7096	193/18670	0.002387	0.02158	0.01609	ZFP36/TSC1/NXF1/SRSF5/NUP62/NUP160/CHTOP/NUP214/FLOT1/ENY2/G3BP2/AGFG1/KHDRBS1/RAN/ALYREF/RNPS1/EIF6/MX2/MAGOHB/SARNP/NUP85/NXT1/CETN3/SEH1L/SIDT1/YTHDC1/BICD2/NUP43/HNRNPA1/NPM1/HNRNPA2B1/PURA/RBM8A/MVP/SNUPN/FYTTD1/DDX19B/DHX9/U2AF1/POM121/ZNF593/SRSF3/SYMPK/XPOT/SFPQ/CPSF3/MYO1C/ATXN2/ARC/RBM27/TST/FIP1L1/NUP88/THOC2/SRSF6/SRSF7/CKAP5/NUP107/CDC40/NPIPA1/THOC5/POLR2D/TOMM20/NXT2/U2AF1L4/EIF5A/NUP93/CETN2/LTV1/THOC6/RIOK2/SSB/SRRM1/NUP205/FMR1/PHAX/SRSF4/EIF4E/NUP50/PARP11/DHX38/MCM3AP/PCID2/HNRNPA3/CPSF2/CPSF1/PNPT1/SIDT2/RRS1/POM121C/AAAS/UPF1/RFTN1	93
BP	GO:0051224	negative regulation of protein transport	93/7096	193/18670	0.002387	0.02158	0.01609	FN1/EZR/PTGER4/IL27RA/ANXA1/IL1R2/RHBDF2/CSK/GBP1/ARG2/SYT11/ERP29/BARD1/TMBIM6/DPH3/LILRA5/NLRP3/CHP1/HADH/TNFAIP3/BANK1/SIRT4/LGR4/ENY2/NLRP12/RGCC/FAM3D/TNF/TNFRSF21/APOE/HMGCR/LILRB1/CD22/RAB23/PIM3/ENHO/CD36/SERPINB1/MAPKBP1/PTPN22/GOPC/CDK5/SP100/RSAD2/IL1B/GDI1/UBE2J1/MDFIC/PML/PPM1F/UBE2G2/LRRK2/CD200R1/KLF7/IDH2/INPP5K/NR1H3/FFAR4/SYTL4/LMAN1/RABGEF1/BTN2A2/DMTN/CPTP/DERL2/F2R/INSIG1/TXN/YOD1/WWP2/PPP1R11/TLR8/SRGN/APOA1/TNFRSF4/FRMD4A/CD34/PKIA/SYT4/NDUFAF2/MAP4K4/C5AR2/CX3CL1/ITGB1BP1/PFKL/NR1H4/TLR6/PSMD9/C1QTNF3/ERLEC1/OS9/GHRL/RHBDF1	93
BP	GO:0002753	cytoplasmic pattern recognition receptor signaling pathway	35/7096	62/18670	0.002399	0.02158	0.01609	NOD2/IRF7/TNFAIP3/BIRC2/UBE2N/DDX60/NFKBIA/RELA/TAB3/TRAF6/IKBKG/TLR4/DDX58/PTPN22/CASP8/CYLD/LSM14A/PUM2/NPLOC4/IFIH1/SEC14L1/TAB1/ANKRD17/BIRC3/ALPK1/UBC/C1QBP/GPATCH3/RIOK3/TIFA/TRIM15/NLRX1/TSPAN6/XIAP/ZCCHC3	35
BP	GO:0032922	circadian regulation of gene expression	35/7096	62/18670	0.002399	0.02158	0.01609	NAMPT/BHLHE40/LGR4/PER2/EGR1/MAGED1/ATF4/CSNK1D/RBM4B/RELB/KDM2A/AHR/PML/SIRT1/PPARGC1A/MYCBP2/CSNK1E/HDAC2/MYBBP1A/KDM8/ID2/PRMT5/PPP1CC/PPP1CA/PPARA/CLOCK/GFPT1/HNF1B/RORA/ARNTL/OGT/PPP1CB/PER3/TOP1/NRIP1	35
BP	GO:0046635	positive regulation of alpha-beta T cell activation	35/7096	62/18670	0.002399	0.02158	0.01609	PNP/CCR2/NFKBIZ/ANXA1/CD55/NLRP3/IL4R/CBFB/PTPRC/SOCS5/ZBTB7B/HLA-E/NFKBID/RASAL3/IL12RB1/LGALS9/EBI3/ADA/HLX/IL18/AP3B1/TNFSF4/SOCS1/IFNG/IL12B/PRKCZ/CD80/PRKCQ/RHOA/CD83/CCL19/MALT1/ZBTB16/CD3E/IL23A	35
BP	GO:0032231	regulation of actin filament bundle assembly	51/7096	97/18670	0.002412	0.02158	0.01609	S100A10/PTGER4/STMN1/FHOD1/TSC1/ARAP1/SORBS3/FLNA/RHOC/S1PR1/RGCC/SLC9A1/ARHGEF10L/EVL/RDX/PFN1/PAK1/SWAP70/ABL1/PPM1F/MKKS/RAC1/ARHGAP6/BBS4/LIMCH1/NRP1/TPM1/INPP5K/CD47/PLEK/SHANK1/LPAR1/PXN/CLASP2/APOA1/TGFB3/SYNPO2L/TACSTD2/TMEFF2/MTOR/RHOA/CX3CL1/ITGB1BP1/MET/WAS/ROCK2/ASAP3/SHANK3/SERPINF2/ALMS1/SYNPO	51
BP	GO:0120162	positive regulation of cold-induced thermogenesis	51/7096	97/18670	0.002412	0.02158	0.01609	EPAS1/CCR2/APPL2/FABP4/STAT6/THRA/HADH/PLAC8/ADIPOR1/PER2/IL4R/CEBPB/JAK2/ZNF516/CPT2/SCD/CD36/LEP/ZBTB7B/DECR1/PDGFC/ADRB1/IGF1R/VEGFA/CMKLR1/OMA1/UCP2/GATM/G0S2/PPARGC1A/GRB10/FH/ADRB2/FFAR4/KSR2/KDM6B/UCP1/FABP5/IL18/ADIPOR2/OGT/DBH/MFAP2/ELOVL6/SLN/DIO2/GJA1/ALMS1/TRPV2/GHRL/PRKAB1	51
BP	GO:0036376	sodium ion export across plasma membrane	11/7096	14/18670	0.002414	0.02158	0.01609	SLC8A1/ATP1A1/SLC9A1/ATP4A/ATP1B2/ATP1B3/FXYD1/ATP1B1/FXYD2/ATP1A2/ATP12A	11
BP	GO:0043558	regulation of translational initiation in response to stress	11/7096	14/18670	0.002414	0.02158	0.01609	PPP1R15A/ATF4/NCK1/NPM1/PPP1R15B/EIF2S1/IMPACT/PPP1CA/EIF2AK2/EIF2AK1/EIF2AK4	11
BP	GO:0050862	positive regulation of T cell receptor signaling pathway	11/7096	14/18670	0.002414	0.02158	0.01609	KCNN4/RELA/CD226/TESPA1/RAB29/LCK/CYLD/TRAT1/PRKD2/ADA/CCR7	11
BP	GO:0001736	establishment of planar polarity	63/7096	124/18670	0.002433	0.02168	0.01617	WNT5A/CELSR2/PSMB9/PSMB8/PSMA5/DVL2/PSMD11/PSME1/DAAM1/PFN1/PSMB10/PSMA1/PSMA4/ROR2/FUZ/ABL1/PAFAH1B1/PSMB1/SAPCD2/PSMC4/INTU/PSMD13/PSMB3/RAC1/PSMB5/PSMD6/PSMC3/AP2A2/PSME3/PSMC6/ROR1/AP2S1/MKS1/FZD5/AP2A1/FZD1/FZD4/DVL1/WNT1/ASTN2/CTHRC1/IFT20/PSMC1/PSMD8/PSMA2/ANKRD6/FZD7/PSMC5/FOXF2/PSMC2/AP2M1/GPC4/PSMB2/PSMD4/RHOA/BRSK1/FZD2/GRHL3/PSMD1/WNT7A/PSMB4/PSMD9/PSMD3	63
BP	GO:0007164	establishment of tissue polarity	63/7096	124/18670	0.002433	0.02168	0.01617	WNT5A/CELSR2/PSMB9/PSMB8/PSMA5/DVL2/PSMD11/PSME1/DAAM1/PFN1/PSMB10/PSMA1/PSMA4/ROR2/FUZ/ABL1/PAFAH1B1/PSMB1/SAPCD2/PSMC4/INTU/PSMD13/PSMB3/RAC1/PSMB5/PSMD6/PSMC3/AP2A2/PSME3/PSMC6/ROR1/AP2S1/MKS1/FZD5/AP2A1/FZD1/FZD4/DVL1/WNT1/ASTN2/CTHRC1/IFT20/PSMC1/PSMD8/PSMA2/ANKRD6/FZD7/PSMC5/FOXF2/PSMC2/AP2M1/GPC4/PSMB2/PSMD4/RHOA/BRSK1/FZD2/GRHL3/PSMD1/WNT7A/PSMB4/PSMD9/PSMD3	63
BP	GO:0016042	lipid catabolic process	152/7096	333/18670	0.002439	0.02168	0.01617	FUCA1/ASAH1/HSD17B14/PLD3/HEXB/ALDH3A2/PLA2G12A/PLBD2/HADHB/FABP4/ENPP2/CYP27A1/SRD5A1/THRA/GM2A/ABHD4/SPP1/PPARD/HADH/ACAA1/GDE1/LIPA/ABHD6/ABHD12/GPCPD1/YWHAH/PHYH/PAFAH2/APOC1/SCARB1/MGST2/PLA2G7/PSAP/MGLL/TNF/PLBD1/SCP2/AKR1C3/APOE/PNPLA6/PLD1/PNPLA3/ETFA/CDK4/CPT2/CYP1B1/AUH/ABCD3/SGPL1/GALC/PCK2/LEP/ECH1/PRKCD/PLA1A/ACADM/NAPEPLD/DDHD1/ACADS/PNPLA7/DECR1/PAFAH1B1/MCEE/IL1B/AIG1/PLA2G15/PLCG2/LDLR/ACOX1/ETFDH/ECI2/PLB1/SLC27A2/HSD17B4/ACACB/LRP1/IDH1/ACOX2/ACBD5/GLA/FABP3/LIPJ/IRS2/BDH2/ABHD3/DECR2/MLYCD/APOA5/PNPLA8/ENPP7/CRTC3/SPHK1/DAGLB/PLA2G3/PCCB/CYP1A2/ECI1/CYP26B1/PRDX6/NUDT19/PNPLA5/ETFB/NAGA/PEX13/TYSND1/CPT1A/EHHADH/INPP5F/ACADVL/HADHA/AKR1B10/PLCD1/STS/PLCB1/NUDT7/FABP5/PPARA/HINT2/PLD4/ACAA2/SRD5A3/CES5A/CES3/PLD2/PLCD4/ACER3/PRKAA1/APOA1/PLCXD3/CYP27B1/NCEH1/ACOX3/PLA2G6/NEU1/BCO2/SMPD1/PIK3CG/CYP26A1/CROT/MTOR/CYP4F3/ABCD1/ABHD16A/SMPD2/CYP46A1/FGF23/HACL1/SESN2/PNPLA4/HAO1/SNX17/ACOT8	152
BP	GO:0010390	histone monoubiquitination	19/7096	29/18670	0.002446	0.02168	0.01617	PAF1/UHRF1/RYBP/TRIM37/PCGF2/ATXN7L3/DDB1/PCGF1/PCGF3/UBE2E1/BCOR/DTX3L/KDM2B/RING1/LEO1/RNF20/DDB2/CUL4B/CDC73	19
BP	GO:0015949	nucleobase-containing small molecule interconversion	19/7096	29/18670	0.002446	0.02168	0.01617	GSR/TXNRD1/AK2/GUK1/CTPS2/AK8/CMPK1/NUDT13/NME3/NME4/GMPR2/NME1/TYMS/RRM2/RRM2B/AK6/DCTD/CTPS1/DUT	19
BP	GO:0044788	modulation by host of viral process	19/7096	29/18670	0.002446	0.02168	0.01617	APOE/PTX3/IFI27/IGF2R/CCL8/TBC1D20/CCNK/CFL1/ANXA2P2/FMR1/FBXL2/SMC3/EIF2AK4/PC/CSF1R/ANXA2/PPIB/NUCKS1/APCS	19
BP	GO:1904029	regulation of cyclin-dependent protein kinase activity	55/7096	106/18670	0.002457	0.02174	0.0162	CDKN2D/CDKN1A/CCNL1/CCND3/TNFAIP3/RGCC/PKD2/CCND2/KAT2B/HEXIM1/CDC37/ACTB/PSRC1/CDK4/GTPBP4/LATS1/TFAP4/CCNG1/CEBPA/CDKN2B/CASP3/SFN/CCNH/CDKN1C/HEXIM2/CCND1/TTBK1/PDGFB/SERTAD1/BCCIP/CCNE1/CDKN1B/CDKN2C/CCNK/CCNL2/CDC25A/CDK5R2/CNPPD1/EGFR/CCNY/ADAM17/IPO7/CCNA1/HERC5/CCNC/CCNYL1/LATS2/HSP90AB1/CCNA2/MEN1/CCNT1/CCNYL2/CCNG2/CCNB3/CCNF	55
BP	GO:0050691	regulation of defense response to virus by host	23/7096	37/18670	0.002465	0.02174	0.0162	PARP9/TNFAIP3/STAT1/IL15/ERCC6/LILRB1/AIM2/SIN3A/DDX58/IL1B/DHX9/MMP12/APOBEC3G/MAVS/DTX3L/TARBP2/IL12RB1/MUL1/IL12B/TRIM6/EIF2AK4/RNF216/IL23A	23
BP	GO:2000142	regulation of DNA-templated transcription, initiation	23/7096	37/18670	0.002465	0.02174	0.0162	DR1/THRA/ZNF451/SRF/PSMC4/MITF/HMGB1/SUB1/CREB1/SETX/PSMC3/CAND1/PSMC6/HEY2/HNF1B/BCLAF1/FOSL1/HNF1A/PSMC5/PSMC2/PAXIP1/WNT10B/TAF7	23
BP	GO:2000403	positive regulation of lymphocyte migration	23/7096	37/18670	0.002465	0.02174	0.0162	CCR2/OXSR1/WNT5A/TNFRSF14/ADAM8/CXCL10/CXCL12/DOCK8/PTK2B/CXCL13/ITGA4/AIF1/CCL5/CCL7/CD99L2/TMEM102/MADCAM1/FADD/ADAM17/CCL20/RHOA/APP/CCL4	23
BP	GO:0002724	regulation of T cell cytokine production	20/7096	31/18670	0.002484	0.02187	0.01631	CCR2/NLRP3/SMAD7/HFE/IL18R1/HLA-F/TRAF6/CLC/RSAD2/IL1B/TRPM4/IL1R1/IL6/FZD5/IL18/TRAF2/TNFSF4/PRKCZ/TBX21/MALT1	20
BP	GO:0014904	myotube cell development	22/7096	35/18670	0.00249	0.02187	0.01631	IGF1/SKI/KLHL41/RYR1/HOMER1/SMYD3/MYOG/BCL2/NFATC2/HDAC4/KLHL40/LMOD3/BIN3/SHOX2/DNER/GPX1/P2RX2/WNT10B/ACTA1/SMO/KEL/MYF6	22
BP	GO:0007584	response to nutrient	104/7096	219/18670	0.002497	0.02187	0.01631	NQO1/SLC8A1/VDR/NOD2/FYN/USF2/CDKN2D/LDHA/GCLM/POR/AIFM1/SOD1/PIM1/DAD1/TMBIM6/PTGS2/SPP1/PPARD/HMGCL/STAT1/AHCY/FOLR2/GDAP1/GSTP1/IL15/P2RX7/HAT1/HMOX1/CXCL10/AKR1C3/AGL/HMGCR/PKM/RELA/PDK2/TGFB1/ARSB/AACS/HMGCS1/ALAD/PANX1/LEP/BCL11A/SRF/BAIAP2/ACSL4/CDKN2B/CAT/GCLC/ABCA1/IL1B/P2RY12/CREB1/IGFBP2/TRPM4/BMP7/CCND1/KYNU/SPARC/NMRAL1/OXCT1/TRIM24/P2RX1/GNAI2/PCNA/CYP26B1/ERCC1/SLC16A1/SETDB1/ITGA2/TYMS/PDX1/CYBA/CYBB/ADA/EGFR/AMIGO1/DNMT3A/HSP90B1/AQP3/ADIPOR2/GIPR/HAMP/MDM2/P2RY4/APOA1/CYP27B1/BCKDHB/GNPAT/OGT/CD4/CYP26A1/MTOR/P2RX2/CIB2/SSH1/MGMT/CD3E/FGF23/ALDH3A1/NNT/NR1H4/P2RY1/P2RX5	104
BP	GO:0046633	alpha-beta T cell proliferation	21/7096	33/18670	0.002498	0.02187	0.01631	CCR2/ELF4/CD55/IRF1/ARG2/TNFRSF14/SH3RF1/PTPRC/IL15/ZBTB7B/HLA-E/RASAL3/CD274/LGALS9/EBI3/IL18/TNFSF4/IL12B/CD3E/TWSG1/IL23A	21
BP	GO:0070232	regulation of T cell apoptotic process	21/7096	33/18670	0.002498	0.02187	0.01631	TSC22D3/PIP/WNT5A/ARG2/SLC46A2/ADAM8/PRELID1/IL7R/DOCK8/HIF1A/IDO1/NFKBID/CCL5/BMP4/CD274/LGALS9/ADA/FADD/PTCRA/PRKCQ/PDCD1	21
BP	GO:0033013	tetrapyrrole metabolic process	34/7096	60/18670	0.002526	0.02209	0.01647	BLVRB/MMADHC/FECH/ABCD4/MTR/HMOX1/CD320/UROD/ALAD/ABCB6/MTRR/CPOX/TMEM14C/SRRD/BDH2/PRSS3/MMAB/CYP1A2/MMACHC/COX15/CTRB2/AMBP/IREB2/LMBRD1/NFE2L1/RSAD1/CLYBL/TCN1/EIF2AK1/ALAS1/SPTA1/CTRC/SLC25A38/SLC25A39	34
BP	GO:0031099	regeneration	95/7096	198/18670	0.002544	0.02222	0.01656	KLF4/IGF1/RTN4R/ANXA1/CDKN1A/GRN/SRSF5/LRIG2/SPP1/PPARD/DUSP10/MAP2K1/MTR/LAMB2/CEBPB/JAK2/GSTP1/CERS2/HFE/EZH2/HMOX1/IFRD1/CXCL12/NREP/ANXA3/PKM/AXL/CSNK2A2/CDK4/TGFB1/CPQ/HGF/CTNNA1/ADAM15/NINJ1/FLT3/FZD9/IGF2R/RAP1A/CSNK2B/LRP1/CCND1/APOA5/SULF2/PTGFRN/LCP1/MYOG/NINJ2/PFKFB1/TARBP2/BCL2/ATIC/PCNA/CDKN1B/TEC/KLF5/NDEL1/PPAT/TYMS/INPP5F/PDX1/RTN4RL1/PRMT5/MYOZ1/CNTF/ULK1/DHFR/EGFR/BIN3/JAM3/WNT1/HAMP/APOA1/RTN4RL2/FPGS/CAPN3/CAD/NR4A3/CCNA2/FZD7/WDR35/LGR6/GPX1/MAP4K4/AURKA/DAG1/PAX7/PNPT1/BAK1/KREMEN1/WNT7A/WNT10B/GJA1/PTCH1/MYF6	95
BP	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	54/7096	104/18670	0.002623	0.02287	0.01705	CRIP1/TRIM32/CDKN2D/CDKN1A/SKIL/BCL2A1/MIF/ACKR3/CD44/SHISA5/TNF/CD74/HMOX1/NUPR1/ERCC6/CXCL12/DYRK2/HNRNPK/USP28/TMEM161A/MCL1/HTRA2/TMEM109/SFN/ABL1/PML/CLU/SIRT1/ELL3/ATM/MUC1/AEN/BCL2L11/NACC2/MLH1/BCL2/BAX/CASP2/DDIT4/HIPK1/BRCA1/TAF9B/BAD/SNAI1/RAD9A/MOAP1/POLB/TOPORS/TRIAP1/BAK1/BCL2L2/ATAD5/HIC1/DDIAS	54
BP	GO:1905897	regulation of response to endoplasmic reticulum stress	45/7096	84/18670	0.002626	0.02287	0.01705	ERP29/PTPN2/TMBIM6/PPP1R15A/PMAIP1/BCAP31/NUPR1/EDEM1/SGTA/WFS1/HSPA5/NCK1/TMEM33/UBE2J1/CLU/SIRT1/PPP1R15B/UBE2G2/EDEM2/LRRK2/RNFT1/BCL2L11/TXNDC12/SERINC3/UBQLN2/BAX/CREB3/PDX1/DNAJB9/DERL2/NFE2L2/ATXN3/NFE2L1/YOD1/BFAR/UBXN1/HYOU1/RNF185/MANF/ERN1/BAK1/USP19/ERLEC1/OS9/ATF6B	45
BP	GO:0010970	transport along microtubule	79/7096	161/18670	0.002645	0.02294	0.0171	APBA1/SUN2/MAP1S/SOD1/BLOC1S2/UCHL1/IFT172/LAMP1/TNPO1/IFT57/KIF3B/KIFAP3/HIF1A/HSPB1/PCM1/DYNLL2/CEP131/BICD2/IFT80/AP3M2/TRAK2/PURA/PAFAH1B1/DTNBP1/CLN3/RHOT2/WDR19/RASGRP1/BLOC1S6/KIF4A/BBS12/SFPQ/IFT46/RPGR/IFT52/FLOT2/BICD1/SYNE2/ARL8A/MAK/HSPB11/TMEM201/BLOC1S3/COPG2/DYNC2LI1/NDEL1/KIF13A/DYNLRB1/DYNLRB2/BLOC1S1/BLOC1S4/LCA5/PEX14/AP3B1/MAP1A/FMR1/IFT20/KIF17/WDR60/KIF1B/AP3M1/KIF5B/TRAK1/IFT22/WDR35/TRAF3IP1/PRKCZ/MREG/KIF1C/APP/IFT74/TRIM58/UXT/KLC3/TTC30B/MGARP/IFT81/ARL8B/TRIM46	79
BP	GO:0035967	cellular response to topologically incorrect protein	79/7096	161/18670	0.002645	0.02294	0.0171	EXTL2/LMNA/HSPA6/TPP1/PTPN2/TMBIM6/PPP1R15A/CREBRF/FKBP14/KLHL15/ATF4/EDEM1/TLN1/WFS1/SSR1/RNF175/HSPA5/NCK1/HERPUD2/TMEM33/PARP16/CREB3L2/UBE2W/SHC1/WIPI1/VAPB/PPP1R15B/CCND1/EIF2S1/SDF2L1/GOSR2/CREB3L4/SERP1/TOR1A/PDIA6/KDELR3/BCL2L11/BAX/CTH/ASNS/RNF126/DERL1/CREB3/TM7SF3/ACADVL/DNAJB9/CANX/DERL2/STUB1/CALR/HSPA1L/NFE2L2/ATXN3/EIF2AK2/YOD1/CTDSP2/HSP90B1/GFPT1/BFAR/POMT2/TBL2/HYOU1/RNF185/RNF5/PPP2R5B/YIF1A/OPTN/VCP/MBTPS2/ERN1/BAK1/MBTPS1/ATXN3L/PREB/DAXX/ARFGAP1/DNAJC18/HDGF/ATF6B	79
BP	GO:0099111	microtubule-based transport	79/7096	161/18670	0.002645	0.02294	0.0171	APBA1/SUN2/MAP1S/SOD1/BLOC1S2/UCHL1/IFT172/LAMP1/TNPO1/IFT57/KIF3B/KIFAP3/HIF1A/HSPB1/PCM1/DYNLL2/CEP131/BICD2/IFT80/AP3M2/TRAK2/PURA/PAFAH1B1/DTNBP1/CLN3/RHOT2/WDR19/RASGRP1/BLOC1S6/KIF4A/BBS12/SFPQ/IFT46/RPGR/IFT52/FLOT2/BICD1/SYNE2/ARL8A/MAK/HSPB11/TMEM201/BLOC1S3/COPG2/DYNC2LI1/NDEL1/KIF13A/DYNLRB1/DYNLRB2/BLOC1S1/BLOC1S4/LCA5/PEX14/AP3B1/MAP1A/FMR1/IFT20/KIF17/WDR60/KIF1B/AP3M1/KIF5B/TRAK1/IFT22/WDR35/TRAF3IP1/PRKCZ/MREG/KIF1C/APP/IFT74/TRIM58/UXT/KLC3/TTC30B/MGARP/IFT81/ARL8B/TRIM46	79
BP	GO:0031663	lipopolysaccharide-mediated signaling pathway	33/7096	58/18670	0.002656	0.02298	0.01713	TLR2/BCL10/LYN/CD55/HCK/TNFAIP3/MIF/LY96/LY86/LILRA2/SCARB1/TNF/NFKBIA/TICAM1/TGFB1/PTAFR/CD36/TRAF6/TLR4/PTPN22/CACTIN/IL1B/CCL5/IL18/MAPK1/SIGIRR/LACRT/LBP/MTDH/CX3CL1/MALT1/PRKCA/SASH1	33
BP	GO:1903749	positive regulation of establishment of protein localization to mitochondrion	33/7096	58/18670	0.002656	0.02298	0.01713	RAC2/PINK1/HPS4/PMAIP1/FBXW7/YWHAH/CSNK2A2/UBE2D3/HTRA2/SFN/CASP8/ATG13/RHOU/PDCD5/ARIH2/MAPK8/ABLIM3/BCL2/MICALL2/GZMB/UBL4B/YWHAQ/SREBF2/FZD5/HSPA1L/PRKAA1/SH3GLB1/YWHAE/BAD/UBL5/PPP1R13B/BAP1/YWHAG	33
BP	GO:0043393	regulation of protein binding	103/7096	217/18670	0.002661	0.02299	0.01714	ARF6/STMN1/PPP2CA/WNT5A/TMBIM6/LFNG/FLOT1/HFE/PCBD1/RAN/APOE/GSK3B/TICAM1/TMC8/CCPG1/ACTB/ARRB1/RAPGEF2/CD36/SYAP1/LRPAP1/PRKCD/ADAM15/NRG1/RUVBL2/ITGA4/BMP2/HSPA5/CDK5/PLK2/ABL1/CTSZ/IFIT2/DTNBP1/MAPRE1/LRP1/SYMPK/CRK/EIF2S1/GPSM1/TTBK1/PDGFB/CYLD/LRRK2/TDG/BTBD1/CSNK1E/DTX3L/MARK3/MAPK8/NRP1/DISC1/MMP9/PLXND1/PLCL1/BCL2/BMP4/BAX/HDAC4/MARK2/PRKACA/ADRB2/DERL1/GTF2F1/IFIT1/STUB1/PPP1CA/PEX14/PPARA/TRAF2/BAG2/ANXA2P2/DVL1/PSEN1/TCF7L2/CTHRC1/EPB41/PLCL2/EFHB/SPTA1/GNL3L/PIN1/HSP90AB1/MEN1/CARM1/TERT/ANXA2/HDAC5/AURKA/APP/PIM2/ITGB1BP1/TTBK2/MET/TIRAP/BAK1/HOXA3/TRAF4/AIDA/GCG/CFHR5/GAS8/MEF2C	103
BP	GO:0097529	myeloid leukocyte migration	100/7096	210/18670	0.002684	0.02316	0.01726	S100A9/S100A8/FPR2/S100A12/CCR2/CX3CR1/PTGER4/RAC2/DUSP1/ANXA1/BST1/LYN/AZU1/IL17RA/FLT1/VEGFB/CAMK1D/MIF/PPBP/LGMN/CXCL9/PLA2G7/CXCL11/ADAM8/CD74/CXCL10/CXCL12/PTPRO/MPP1/IRAK4/NUP85/PTK2B/SWAP70/ROR2/CXCL13/CD99/VEGFA/PDE4B/CMKLR1/IL1B/AIF1/AGER/CCL5/P2RY12/HMGB1/TNFRSF11A/CCL7/IL1RN/IL1R1/RAC1/CXCR1/IL6/PDGFB/CD200R1/CKLF/RPS19/C3AR1/MOSPD2/CCL13/CD99L2/CCL8/SERPINE1/PIK3CD/CD47/CREB3/CD300A/MMP14/MCOLN2/PLCB1/MST1/C1QBP/VAV1/CXCR2/CCL20/JAM3/PREX1/SLIT2/CCL26/TREM2/CSF3R/PIK3CG/LBP/PRTN3/TRPV4/C5AR2/DAPK2/CX3CL1/CCL19/TIRAP/CCL4/CCR7/GREM1/CCL24/SLAMF8/IL23A/IL17RC/CXCL6/PDGFD/S100A14/IL37	100
BP	GO:0046165	alcohol biosynthetic process	85/7096	175/18670	0.002701	0.02327	0.01735	VDR/ASAH1/GCH1/POR/CYP27A1/SOD1/AKR1B1/NFYC/GPAM/SQLE/TNF/IMPAD1/PCBD1/NFKB1/RAN/APOE/HMGCR/HMGCS1/PTAFR/IP6K1/SCD/PTK2B/PCK2/LEP/ERLIN1/P2RY6/CNBP/BMP2/SPTLC2/ACLY/IL1B/PLCG2/PPIP5K2/ERLIN2/FDPS/QDPR/ACACB/PTS/G6PD/FGF1/ARV1/TM7SF2/APOA5/SPR/SPHK1/MSMO1/IDI1/BMP5/PLCL1/SCAP/IMPA2/ABCG1/SC5D/PLEK/SREBF2/CYB5R3/PLCD1/INSIG1/PLCB1/DHFR/NUS1/DHDDS/ACAA2/IPPK/SRD5A3/PLCD4/ACER3/PRKAA1/APOA1/CYP27B1/PLCL2/IFNG/DBH/PCBD2/MBTPS2/SNCA/ELOVL6/CD244/MBTPS1/KPNB1/CACNA1H/ADCYAP1R1/P2RY1/NTSR1/IMPA1	85
BP	GO:0042795	snRNA transcription by RNA polymerase II	39/7096	71/18670	0.002738	0.02348	0.01751	ELL2/NABP1/SNAPC3/POU2F1/POU2F2/INTS5/GTF2E1/INTS7/TAF11/GTF2F2/INTS9/POLR2L/SNAPC1/SNAPC2/ELL3/CDK9/TAF5/RPRD1B/INTS8/POLR2H/RPRD2/CCNK/GTF2F1/INTS3/POLR2F/POLR2D/INTS2/GTF2A1/POLR2K/PHAX/RPAP2/TBP/CCNT1/SNAPC4/SRRT/INTS4/ICE1/POLR2I/INTS6	39
BP	GO:0051057	positive regulation of small GTPase mediated signal transduction	39/7096	71/18670	0.002738	0.02348	0.01751	IGF1/RTN4R/LYN/NOTCH2/RASGEF1A/KITLG/ALS2/P2RY8/JAK2/SHOC2/AKAP13/KRAS/ARRB1/NRG1/EPOR/HRAS/RASGRP1/SHC1/RAC1/MAPRE2/LPAR6/IRS2/STK19/GPR18/GRB2/LPAR1/F2R/RASGRF1/VAV1/GPR35/APOA1/SYNPO2L/RELN/MAP4K4/P2RY10/GPR20/ADCYAP1R1/MMD2/RASGRP4	39
BP	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	49/7096	93/18670	0.002743	0.02348	0.01751	PSMB9/CUL1/PSMB8/HUS1B/PSMA5/PSMD11/PSME1/GPR132/TAOK3/ZNF830/PSMB10/PSMA1/PSMA4/SYF2/PSMB1/PSMC4/DONSON/PSMD13/PSMB3/PSMB5/PSMD6/ATM/PSMC3/PSME3/RAD17/PSMC6/FHL1/FOXO4/TICRR/MIIP/BRCA1/PSMC1/CLSPN/PSMD8/PSMA2/FBXL7/TOPBP1/PSMC5/PSMC2/PSMB2/PSMD4/AURKA/BRSK1/RBX1/PSMD1/PSMB4/ZFYVE19/PSMD9/PSMD3	49
BP	GO:0036473	cell death in response to oxidative stress	49/7096	93/18670	0.002743	0.02348	0.01751	FYN/ATG7/PINK1/TSC1/SOD1/ZNF622/FBXW7/JAK2/PSAP/SLC7A11/ATF4/CYP1B1/HGF/HIF1A/HSPB1/MAPK7/PRKCD/MCL1/HTRA2/TLR4/NCOA7/PML/SIRT1/SFPQ/LRRK2/MIR34A/VNN1/BCL2/MMP3/PDK1/GSKIP/MAP3K5/FZD1/NFE2L2/TXN/WNT1/NR4A3/LANCL1/DIABLO/GPX1/PDE8A/BAG5/PDCD10/SIGMAR1/MET/ENDOG/TLR6/FOXO3/OXR1	49
BP	GO:0046634	regulation of alpha-beta T cell activation	49/7096	93/18670	0.002743	0.02348	0.01751	PNP/CCR2/NFKBIZ/ANXA1/CD55/IRF1/ARG2/TNFRSF14/BCL6/NLRP3/SH3RF1/SMAD7/IL4R/CBFB/PTPRC/HFE/LILRB1/SOCS5/ZBTB7B/HLA-E/NFKBID/AGER/RASAL3/HMGB1/IL12RB1/CD300A/CD274/LGALS9/EBI3/ADA/HLX/IL18/AP3B1/TNFSF4/SOCS1/IFNG/IL12B/PRKCZ/CD80/TBX21/PRKCQ/RHOA/CD83/CCL19/MALT1/ZBTB16/CD3E/TWSG1/IL23A	49
BP	GO:0006749	glutathione metabolic process	32/7096	56/18670	0.002791	0.02379	0.01774	GCLM/SOD1/MGST2/GSTP1/SLC7A11/GSR/GGCT/ETHE1/GCLC/GSTZ1/GSTA1/HAGH/IDH1/GPX4/GSTM3/G6PD/ALDH5A1/MGST1/MMACHC/GSTM5/GSS/CNDP2/HPGDS/GSTM4/NFE2L2/NFE2L1/GGT7/GGT5/CHAC2/GPX1/GGTLC1/CTNS	32
BP	GO:0016925	protein sumoylation	44/7096	82/18670	0.002794	0.02379	0.01774	HMG20A/NUP62/ZBED1/NUP160/NUP214/EGR1/SENP6/RELA/ZNF451/NUP85/SEH1L/BCL11A/NUP43/NSMCE2/POM121/TRPM4/EGR2/SUMO1/IFIH1/UBA2/NUP88/HDAC4/TOLLIP/NUP107/CBX4/ARNT/PIAS3/MUL1/NUP93/NUP205/MDM2/CAPN3/RNF212B/NUP50/SUMO4/UBE2I/GNL3L/TOPORS/HMG20B/GNL3/KIAA1586/RASD2/POM121C/AAAS	44
BP	GO:0032637	interleukin-8 production	44/7096	82/18670	0.002794	0.02379	0.01774	KLF4/MYD88/NOD2/TLR1/TLR2/ANXA1/CLEC7A/BCL10/WNT5A/CD58/FCN1/CD2/LILRA2/PTPRC/TNF/CD74/ARRB1/FFAR2/TLR5/LEP/MAPKBP1/HYAL2/TLR4/DDX58/PTPN22/CACTIN/IL1B/CHI3L1/MAVS/ZNF580/PRKD2/SERPINE1/LGALS9/F2R/FADD/TLR8/TLR3/MAP2K5/LBP/CD33/C5AR2/TIRAP/CD244/TLR6	44
BP	GO:0034644	cellular response to UV	44/7096	82/18670	0.002794	0.02379	0.01774	CRIP1/BMF/CDKN1A/PTGS2/MYC/ERCC4/ATF4/MAPK13/METTL3/USP28/RUVBL2/ZBTB1/HYAL2/TMEM161A/DDB1/NPM1/SIRT1/EIF2S1/RHNO1/POLH/ACTR5/PCNA/NEDD4/BAX/NOC2L/ERCC1/YY1/CDC25A/ST20/HYAL3/SDE2/IMPACT/C9orf116/E2F4/ATR/FMR1/MDM2/DDB2/POLD1/RBL2/CUL4B/EIF2AK4/TRIAP1/BAK1	44
BP	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	53/7096	102/18670	0.002801	0.02381	0.01775	CDKN2D/CDKN1A/CCNL1/CCND3/TNFAIP3/RGCC/PKD2/CCND2/KAT2B/HEXIM1/CDC37/ACTB/PSRC1/CDK4/GTPBP4/LATS1/TFAP4/CCNG1/CEBPA/CDKN2B/CASP3/SFN/CCNH/CDKN1C/HEXIM2/CCND1/PDGFB/SERTAD1/BCCIP/CCNE1/CDKN1B/CDKN2C/CCNK/CCNL2/CDC25A/CDK5R2/CNPPD1/EGFR/CCNY/ADAM17/IPO7/CCNA1/HERC5/CCNC/CCNYL1/LATS2/CCNA2/MEN1/CCNT1/CCNYL2/CCNG2/CCNB3/CCNF	53
BP	GO:0000082	G1/S transition of mitotic cell cycle	129/7096	279/18670	0.002851	0.02418	0.01803	KLF4/PTPN6/ANXA1/CDKN2D/CDKN1A/GPNMB/CCND3/CUL1/MCM6/MEPCE/ZNF655/MYC/MCM2/RGCC/SLFN11/EZH2/LSM11/KHDRBS1/SKP2/PKD2/GIGYF2/GMNN/PSME1/BTG2/CCND2/GPR132/CDK4/RDX/ORC5/RPA1/E2F6/LATS1/CDKN2B/PLK2/SFN/PRIM2/CCNH/ZPR1/AIF1/KLF11/PML/CDK2AP2/CCND1/ACVR1B/RCC1/RHOU/DDX3X/ATM/TNKS1BP1/PPP6C/MUC1/KMT2E/CTDSPL/PLK3/PSME3/NACC2/UBE2E2/CCNE1/BCL2/PCNA/ORC6/BAX/USP26/ANKRD17/CRADD/ID2/CASP2/CTDSP1/RFWD3/CDKN1B/CDKN2C/CNOT4/FHL1/CDC25A/INHBA/PPAT/PLAGL1/CACUL1/ARID3A/TYMS/ORC4/RRM2/BTN2A2/CAMK2A/NPAT/E2F4/PLCB1/DHFR/EGFR/CNOT7/GML/ADAM17/CTDSP2/MCM5/MDM2/CCNA1/CUL2/EIF4G1/WEE1/RBL2/MTBP/DCUN1D3/EIF4E/BACH1/LATS2/NASP/CUL4B/TMEM14B/RB1/CNOT10/POLA1/CARM1/JADE1/POLA2/ORC3/TERT/ESRRB/MCM8/HINFP/TRIAP1/AURKA/PIM2/CDC73/SOX4/POLE4/PRMT1/USP37/KIF14/E2F8	129
BP	GO:0030111	regulation of Wnt signaling pathway	164/7096	363/18670	0.002851	0.02418	0.01803	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	164
BP	GO:0051353	positive regulation of oxidoreductase activity	31/7096	54/18670	0.002928	0.0248	0.01849	HTR2B/VDR/NOD2/GCH1/POR/GNAI3/SCARB1/TNF/KRAS/APOE/HIF1A/PTK2B/ABL1/IL1B/RFK/CHCHD10/FCER2/GNAI2/CYBA/PDP2/DHFR/ABL2/NUS1/CYP27B1/IFNG/ATP7A/PDP1/TERT/CDH3/SNCA/FGF23	31
BP	GO:0001780	neutrophil homeostasis	12/7096	16/18670	0.002958	0.02486	0.01853	CCR2/ANXA1/SLC7A11/AXL/PDE4B/HMGB1/IL6/PIK3CD/CXCR2/JAM3/MERTK/PIK3CB	12
BP	GO:0006047	UDP-N-acetylglucosamine metabolic process	12/7096	16/18670	0.002958	0.02486	0.01853	PGM3/GNPDA1/UAP1/NAGK/RENBP/GNPNAT1/SLC35A3/UAP1L1/GFPT1/GNE/GFPT2/DPAGT1	12
BP	GO:0030214	hyaluronan catabolic process	12/7096	16/18670	0.002958	0.02486	0.01853	HEXB/CHP1/CD44/SLC9A1/HEXA/TGFB1/HYAL2/GUSB/HYAL3/CEMIP/STAB2/LYVE1	12
BP	GO:0043174	nucleoside salvage	12/7096	16/18670	0.002958	0.02486	0.01853	TYMP/UPP1/ADK/TK1/PRTFDC1/MTAP/DCK/UCK1/TK2/CDA/UCKL1/UPP2	12
BP	GO:0090335	regulation of brown fat cell differentiation	12/7096	16/18670	0.002958	0.02486	0.01853	METRNL/FNDC5/PTGS2/DUSP10/LEP/NAPEPLD/ZBTB7B/SIRT1/FTO/MTOR/TRPV4/VSTM2A	12
BP	GO:2001170	negative regulation of ATP biosynthetic process	12/7096	16/18670	0.002958	0.02486	0.01853	CBFA2T3/FBP1/STAT3/NUPR1/PPARGC1A/FLCN/MYOG/PFKFB1/HDAC4/DDIT4/PPARA/PID1	12
BP	GO:0022617	extracellular matrix disassembly	43/7096	80/18670	0.002974	0.02496	0.01861	CAPN2/TIMP2/CTSS/FLOT1/CD44/CTSK/A2M/ADAM8/CST3/DPP4/KIF9/TGFB1/ADAM15/FURIN/MMP12/CAPNS2/LRP1/TPSAB1/IL6/ETS1/KLK4/LCP1/MMP9/TIMP1/MMP3/HTRA1/CTRB2/CTSV/MMP1/MMP14/CLASP2/CMA1/FSCN1/CTSG/MMP2/MMP10/MMP16/MMP19/ADAMTS4/TLL2/SCUBE3/CAPNS1/PRSS2	43
BP	GO:0009206	purine ribonucleoside triphosphate biosynthetic process	83/7096	171/18670	0.003079	0.02581	0.01924	IGF1/CBFA2T3/HK3/LDHA/PINK1/FBP1/PGK1/VPS9D1/STAT3/PFKFB3/NUP62/NUP160/PFKM/PFKP/GAPDH/NUP214/SLC2A6/P2RX7/NUPR1/PGAM1/PKM/GALK1/EIF6/TPI1/ZBTB7A/TGFB1/NUP85/HIF1A/SEH1L/INSR/ALDOC/NUP43/IMPDH1/ENO1/DNAJC30/ALDOA/POM121/OGDH/GPI/PFKFB4/PPARGC1A/FLCN/DHTKD1/NME3/SLC25A12/LDHC/NME4/PRKAG2/MYOG/NCOR1/PFKFB1/NUP88/HDAC4/NME1/NUP107/FOXK2/DDIT4/PGK2/PFKFB2/ARNT/PPARA/NUP93/SLC25A13/PRKAA1/PSEN1/NUP205/ENO2/PID1/SLC4A1/TREM2/NUP50/IFNG/PRKAG1/OGT/ESRRB/ZBTB20/VCP/ADPGK/TAZ/APP/PFKL/POM121C/AAAS	83
BP	GO:0060271	cilium assembly	165/7096	366/18670	0.003086	0.02583	0.01926	ARMC9/PRKAR2B/TMEM138/TUBA1A/NINL/ATG3/RILPL1/HYLS1/BBS5/TCTN1/RAB11A/FLNA/RFX2/SNX10/TTC8/FOPNL/LRRC6/IFT172/ODF2/KCTD17/TNPO1/IFT57/HAUS8/ACTR2/BBS10/CNTRL/KIF3B/RAB23/KIFAP3/CEP164/MAP4/PCM1/DYNLL2/CSNK1D/ARL13B/WDR11/CEP131/CBY1/IFT80/FUZ/SPAG1/SFI1/PAFAH1B1/CDK5RAP2/C5orf30/WDR19/INTU/CEP76/MAPRE1/EHD1/BBS2/RAB8A/RFX3/GORAB/MKKS/IFT46/CCDC88A/TTC39C/OCRL/RPGR/DNAL1/CYLD/IFT52/ADAMTS16/ATP6V1D/B9D1/BBS4/CSNK1E/TCTN2/SYNE2/HAUS2/PLA2G3/NPHP4/MAK/ABLIM3/DISC1/HSPB11/DNM2/AVIL/WDPCP/DNAI2/UBXN10/KIF24/PRKACA/CKAP5/DCTN2/DNAAF2/DYNC2LI1/CEP152/TUBA4A/RSPH9/BBS7/TBC1D7/MKS1/TTLL3/CCDC151/DYNLRB1/CCDC65/DYNLRB2/ACTR3/CEP63/KIF27/E2F4/FAM161A/CEP57/CETN2/RSPH6A/HAUS5/TUBB4A/PIH1D3/HAUS1/BBS9/TMEM231/CEP19/TCHP/PTPDC1/IFT20/YWHAE/CEP83/TTLL1/DNAI1/KIF17/TPGS1/WDR60/TMEM80/FGFR1OP/UNC119B/CCDC13/PKHD1/EHD3/IFT22/ATXN10/WDR35/YWHAG/LRRC61/ABCC4/TRAF3IP1/SNAP29/TCTN3/CEP120/DZIP1L/CCDC28B/VDAC3/TEKT3/TTBK2/TMEM107/CEP78/IFT74/CCDC63/ASAP1/NEK8/SPAG17/CCDC66/UBE2B/DNAH8/TTC30B/IFT81/RP1/POC1B/C2CD3/ALMS1/GAS8/WRAP73/SPATA6/ABLIM1	165
BP	GO:0046328	regulation of JNK cascade	89/7096	185/18670	0.003094	0.02586	0.01928	NOD2/PINK1/WNT5A/ZNF622/SH3RF1/DUSP10/GSTP1/DVL2/TNF/ERCC6/ZEB2/MAP3K4/SLAMF1/DUSP3/TAOK3/GADD45B/PAK1/MAP4K5/PTK2B/ROR2/TRAF6/NCF1/TLR4/PTPN22/TPD52L1/IGF1R/HRAS/PAFAH1B1/IL1B/DTNBP1/AGER/MAP3K12/RASGRP1/SDCBP/MDFIC/HMGB1/TNFRSF11A/IL1RN/MFHAS1/DUSP19/MAP4K2/CYLD/NCOR1/EDAR/MAP3K6/MAP4K1/ZMYND11/MLKL/MAP3K11/SH3RF3/FZD5/AMBP/BIRC7/MAP3K5/PLCB1/EGFR/MUL1/TRAF2/FZD4/MAP2K4/MAP3K13/PPEF2/EPHB1/HIPK3/DNAJA1/ANKRD6/ULK4/TLR3/FZD7/MEN1/MAP4K4/TRPV4/APP/ERN1/PDCD4/CCL19/TIRAP/TRAF4/AIDA/WNT7A/CCR7/DAXX/SERPINF2/TLR6/FZD10/NRK/SASH1/IL37/MAP3K9	89
BP	GO:0002429	immune response-activating cell surface receptor signaling pathway	209/7096	473/18670	0.003114	0.02597	0.01936	SH2B2/MYO1G/FPR2/FPR1/FYN/ICAM2/EZR/KCNN4/NFKBIZ/PTPN6/APPL2/BCL10/LYN/FCGR1A/ICAM3/CSK/GBP1/CLEC4D/MNDA/PTPN2/HCK/FCN1/PSMB9/PLSCR1/CUL1/CLEC4E/LPXN/PLEKHA1/PSMB8/BTN2A1/LILRA2/CBFB/PTPRC/UBE2N/PSMA5/PSMD11/PRKACB/TNFRSF21/NFKB1/KRAS/PSME1/ACTR2/DUSP3/LCP2/CD22/RELA/DENND1B/ACTB/CD226/LAT2/FFAR2/PAK1/PSMB10/PSMA1/PSMA4/PRKCD/TAB3/LILRB4/TRAF6/IKBKG/BAIAP2/EIF2B5/PTPN22/FGR/HLA-DPB1/HLA-DPA1/NCK1/CD209/PDE4B/HRAS/RELB/CYFIP2/ABL1/SLC39A10/CMKLR1/NFKBID/PSMB1/PAK2/PSMC4/THEMIS2/ARPC1A/CD3D/PLCG2/RAP1A/PSMD13/ICOSLG/TRAC/MUC2/CRK/RAF1/PSMB3/RBCK1/TESPA1/RAC1/RAB29/ELF1/TRBC1/ARPC1B/ITK/LCK/HLA-DRA/CYLD/CR1/CYFIP1/MYO1C/CTLA4/PSMB5/PTK2/PSMD6/MIR34A/BTN3A2/MUC1/PSMC3/C3AR1/TRAT1/TAB1/PSME3/WIPF2/BCL2/PRKD2/BAX/CD247/PSMC6/NFATC2/PIK3CD/CD47/MS4A1/PRKACA/NRAS/TEC/BTN3A3/CR2/CD3G/GRB2/CD300A/LAX1/GCSAM/RABGEF1/BTN2A2/ADA/ACTR3/ELMO1/THEMIS/VAV1/CD276/PLD2/NFAM1/PSEN1/BTN3A1/MAPK1/HLA-DQB2/PAG1/MUC6/PSMC1/PRAM1/PLA2G6/EIF2B1/ARPC4/MYO10/PSMD8/PSMA2/PLCL2/SKAP1/NCR3/NR4A3/TXK/CD4/MUCL1/EIF2B3/HSP90AB1/FCGR2A/CACNB3/MYH2/PSMC5/WIPF1/SLA2/ARPC2/PSMC2/PSMB2/PSMD4/PRKCQ/FOXP1/LIME1/C5AR2/PAX5/MALT1/CHUK/PSMD1/CCR7/WAS/EIF2B2/CD3E/APPL1/PSMB4/CMTM3/CACNA1F/PSMD9/UBASH3A/NCKAP1/MOG/PSMD3/LAT/ELMO2/IGHD/MEF2C/PIK3CB/PTPRJ/RFTN1/PHPT1	209
BP	GO:0045017	glycerolipid biosynthetic process	117/7096	251/18670	0.003115	0.02597	0.01936	FPR2/HTR2B/LPCAT2/SLC27A1/CDS1/PLA2G12A/CHPT1/DGKA/CAPN2/GPAM/PLSCR1/PLEKHA1/MTMR12/FBXW7/SIK1/PIGV/CDS2/PIGP/GK/SCARB1/PTDSS2/PTPMT1/PIGK/PIK3R3/PTPN13/PLD1/PNPLA3/SACM1L/CSNK2A2/PIGN/STARD10/PCK2/SYNJ1/NR1H2/PITPNM1/DDHD1/ACSL4/FIG4/AGPAT3/PLCG2/LDLR/PIK3R6/CSNK2B/PIGF/SYNJ2/STARD7/CDIPT/DGAT2/FABP3/PIGB/DPM1/OCRL/PDGFB/ABHD3/AGPAT4/GPAA1/SH3YL1/RAB38/ATM/ARF1/CRLS1/PIGM/MFSD2A/PLEKHA8/SBF1/LCAT/MTMR4/MPPE1/INPP5K/MTMR6/PIK3CD/NR1H3/PI4K2A/RAB5A/PIGQ/ACP6/MTMR2/INPP5F/PDGFA/FAR1/PIGO/CHKA/PIGH/FABP5/AGK/AGPAT5/PLD2/CPNE1/DPM3/MTMR3/PLEKHA3/APOA1/PLA2G6/PIGT/GNPAT/CPNE3/MTMR9/SLC44A2/PIK3CG/AGPAT1/PIP5K1B/CHAT/TAZ/VAC14/LPCAT1/CHKB/PGS1/AGPAT2/PGAP3/INPPL1/THRSP/NR1H4/ARF3/PGAP1/PIK3CB/IMPA1/PI4KB	117
BP	GO:0006094	gluconeogenesis	47/7096	89/18670	0.00312	0.02598	0.01937	FBP1/PGK1/MDH1/PTPN2/GAPDH/SIK1/PER2/SLC37A4/KAT2B/PGAM1/ATF4/PDK2/TPI1/PCK2/LEP/ALDOC/DDB1/ENO1/ALDOA/SLC25A10/SLC35B4/CRTC2/SIRT1/GPI/DGAT2/PPARGC1A/NLN/SLC25A12/PFKFB1/FOXK2/GOT2/PGK2/SERPINA12/MST1/PPARA/SLC25A13/KAT2A/ENO2/OGT/PC/GCG/SESN2/RBP4/C1QTNF3/WDR5/G6PC/FAM3A	47
BP	GO:0031124	mRNA 3'-end processing	51/7096	98/18670	0.003193	0.02652	0.01977	PCF11/SRSF5/BARD1/ZC3H14/CHTOP/LSM11/PAF1/CSTF3/ALYREF/RNPS1/MAGOHB/SARNP/RBM8A/U2AF1/SRSF3/SYMPK/CPSF3/CDK9/RPRD1B/CLP1/PAPOLA/SCAF8/MTPAP/SNRPA/FIP1L1/RPRD2/THOC2/SRSF6/CPEB1/SRSF7/CDC40/CSTF1/CPEB3/THOC5/POLR2D/LEO1/RNF20/AHCYL1/U2AF1L4/THOC6/SRRM1/SRSF4/DHX38/CPSF2/CCNT1/APP/CDC73/CPSF1/PNPT1/CPSF7/ZNF473	51
BP	GO:0050764	regulation of phagocytosis	51/7096	98/18670	0.003193	0.02652	0.01977	FPR2/IL2RG/TLR2/CLEC7A/APPL2/ATG3/SLC11A1/CSK/AZU1/SOD1/SYT11/HCK/LYAR/CAMK1D/SCARB1/PTPRC/IL15/TNF/RAB31/TGFB1/CD36/PTX3/FGR/IL2RB/ABR/IL1B/SIRPB1/RAP1A/CD300LF/LRP1/HMGB1/BCR/SPHK1/IL15RA/DNM2/CD47/ITGA2/CD300A/CYBA/CALR/ABCA7/MERTK/APOA1/SIRPG/TREM2/IFNG/PRTN3/TULP1/APPL1/RAB27A/PTPRJ	51
BP	GO:0042398	cellular modified amino acid biosynthetic process	29/7096	50/18670	0.00321	0.02659	0.01983	SLC27A1/GCH1/GCLM/ALDH9A1/PLSCR1/ALDH7A1/PTDSS2/MGST2/SLC7A11/GGCT/ACADM/GCLC/GATM/HAGH/PLOD1/ATIC/PLOD2/GSS/CNDP2/GAMT/NFE2L2/SHMT1/DHFR/GGT7/GGT5/FPGS/CHAC2/CHDH/CKMT2	29
BP	GO:0070671	response to interleukin-12	29/7096	50/18670	0.00321	0.02659	0.01983	SERPINB2/TALDO1/LMNB1/SOD1/RAP1B/MIF/PITPNA/JAK2/HNRNPA2B1/PAK2/GSTO1/CAPZA1/SNRPA1/ARF1/MTAP/CNN2/LCP1/CD47/TYK2/CFL1/IL12RB1/PLCB1/MSN/IFNG/JAK1/IL12B/ANXA2/PDCD4/AIP	29
BP	GO:1904950	negative regulation of establishment of protein localization	94/7096	197/18670	0.003275	0.0271	0.0202	FN1/EZR/PTGER4/IL27RA/ANXA1/IL1R2/RHBDF2/CSK/GBP1/ARG2/SYT11/ERP29/BARD1/TMBIM6/DPH3/LILRA5/NLRP3/CHP1/HADH/TNFAIP3/BANK1/SIRT4/LGR4/ENY2/NLRP12/RGCC/FAM3D/TNF/TNFRSF21/APOE/HMGCR/LILRB1/CD22/RAB23/PIM3/ENHO/CD36/SERPINB1/MAPKBP1/PTPN22/GOPC/CDK5/SP100/RSAD2/IL1B/GDI1/UBE2J1/MDFIC/PML/PPM1F/UBE2G2/LRRK2/CD200R1/KLF7/IDH2/INPP5K/NR1H3/FFAR4/SYTL4/LMAN1/RABGEF1/BTN2A2/DMTN/CPTP/DERL2/F2R/INSIG1/TXN/YOD1/WWP2/PPP1R11/TLR8/SRGN/APOA1/TNFRSF4/FRMD4A/DNAJA1/CD34/PKIA/SYT4/NDUFAF2/MAP4K4/C5AR2/CX3CL1/ITGB1BP1/PFKL/NR1H4/TLR6/PSMD9/C1QTNF3/ERLEC1/OS9/GHRL/RHBDF1	94
BP	GO:0018394	peptidyl-lysine acetylation	82/7096	169/18670	0.003287	0.02715	0.02024	SPI1/POR/BAZ1A/DR1/LDB1/MORF4L2/HAT1/SUPT7L/KAT2B/MRGBP/TRIM16/TGFB1/SIN3A/ZNF451/JADE3/ARRB1/NCOA3/PCGF2/RUVBL2/RUVBL1/EPC2/MBIP/MSL3/MBD3/KAT7/YEATS4/SETD5/TAF5L/IL1B/KAT8/TAF12/CRTC2/SIRT1/NAA40/BRD8/TAF5/PPARGC1A/FLCN/MCRS1/MUC1/HDAC2/KAT5/ELP3/BRPF1/NOC2L/DPF2/CTCF/RSF1/PHF20/ZMPSTE24/BLOC1S1/TAF6L/BRCA1/ING3/HINT2/KANSL1L/CLOCK/EPC1/KAT2A/PRKAA1/PHF10/CPA4/TAF9B/EID1/OGT/MCM3AP/ING4/SET/JADE1/USP22/SNCA/MSL1/SOX4/POLE4/TADA3/PAXIP1/ACTL6A/KLF15/KAT6B/WDR5/TAF7/NAA60	82
BP	GO:0009743	response to carbohydrate	108/7096	230/18670	0.00329	0.02715	0.02024	SLC8A1/NAMPT/TRA2B/CLEC7A/LDHA/ACVR2B/ATG7/LYN/GCLM/TXNIP/RAP1B/PTGS2/PPARD/SMAD2/ENY2/GSTP1/ME1/EGR1/HMGCR/LRP5/TGFB1/PPP3CB/SIN3A/AACS/UNC13B/FIS1/ARRB1/HIF1A/PIM3/PTK2B/PCK2/LEP/SRF/MAPK13/EIF2B5/KAT7/IGF1R/CAT/CASP3/GCLC/IL1B/AGER/C2CD2L/RAP1A/MPC2/LRP1/RAF1/TRPM4/RAC1/IRS2/ZNF236/PPARGC1A/KLF7/SPARC/SRI/OXCT1/POLG/KHK/GPR27/ERCC1/CDKN1B/NME1/RMI1/PRKACA/LGALS1/ITGA2/CTSV/PDX1/CYBA/PTPRN2/PFKFB2/HMGN3/CMA1/GIPR/PRKAA1/TCF7L2/MAP2K4/COL4A3/BAD/PLA2G6/EIF2B1/HNF1B/KIF5B/EIF2B3/MEN1/WDR35/ZBTB20/NDUFAF2/MAP4K4/RHOA/ERN1/SLC9B2/P2RX2/SOX4/SIDT2/GCG/EIF2B2/PFKL/ENDOG/GJA1/NR1H4/STXBP4/SESN2/UCN3/FOXO3/GHRL/MIR146A/PHPT1	108
BP	GO:1902903	regulation of supramolecular fiber organization	159/7096	352/18670	0.003298	0.02716	0.02025	MYADM/S100A10/CDC42EP4/VASP/PTGER4/ARF6/STMN1/MAP1S/FHOD1/TSC1/C9orf72/ARAP1/SORBS3/HCK/RHOBTB1/PLEKHG2/FLNA/RHOC/S1PR1/CIB1/RGCC/TMSB10/SPIRE1/AKAP13/SLC9A1/IQGAP2/APOE/ARHGEF10L/ACTR2/CXCL12/TMOD3/LIMA1/HCLS1/EVL/PSRC1/TWF2/RDX/PFN1/CDC42EP2/PAK1/CLIP1/PTK2B/CFL2/CAPZA2/SWAP70/PRKCD/LATS1/GMFG/CORO1A/BAIAP2/ARFGEF1/CAPG/NCK1/ABL1/FCHSD1/CDK5RAP2/ARPC1A/LDLR/ARHGEF2/CAPZA1/MAPRE1/CLU/PPM1F/MKKS/SH3BP1/RAC1/ARPIN/SPTBN1/ARPC1B/CDC42EP3/CDH5/CYFIP1/MYO1C/CORO1B/ARHGAP6/BBS4/LIMCH1/ARF1/ARPC5L/NRP1/COTL1/TPM1/AVIL/INPP5K/CD47/CDKN1B/CFL1/KANK1/TRIOBP/ARHGAP18/ADD3/RANGRF/GRB2/PLEK/JMY/ACTR3B/SHANK1/FER/SEMA5A/LPAR1/DMTN/SLC39A12/ACTR3/PXN/CLASP2/LMOD3/CAV3/SCIN/PREX1/SLIT2/CCL26/TUBB4A/MAP1A/PSEN1/APOA1/KATNB1/ARPC4/TGFB3/SPTA1/SLAIN2/RB1/SPTBN2/SYNPO2L/TACSTD2/TMEFF2/ARPC2/KANK3/GPX1/MTOR/NAV3/RHOA/TRPV4/PICK1/APP/SNCA/CX3CL1/CLIP3/ITGB1BP1/TTBK2/IAPP/SNX9/MET/FGF13/CCR7/WAS/ROCK2/RHOBTB2/CCL24/ASAP3/SHANK3/AEBP1/SERPINF2/BIN1/NCKAP1/FCHSD2/ALMS1/MEF2C/SYNPO/FMN1	159
BP	GO:0006986	response to unfolded protein	85/7096	176/18670	0.0033	0.02716	0.02025	EXTL2/LMNA/HSPA6/TPP1/PTPN2/TMBIM6/PPP1R15A/FBXO6/CREBRF/FKBP14/ATF4/TMEM129/EDEM1/TLN1/DNAJB1/WFS1/HSPB1/SSR1/RNF175/HSPA5/NCK1/HERPUD2/TMEM33/PARP16/CREB3L2/DNAJB5/SHC1/ERP44/WIPI1/VAPB/PPP1R15B/CCND1/EIF2S1/TOR1B/GOSR2/EDEM2/CREB3L4/SERP1/DNAJB4/PDIA6/KDELR3/BCL2L11/STT3B/BAX/CTH/ASNS/DNAJC4/DERL1/CREB3/TM7SF3/ACADVL/DNAJB9/CANX/DERL2/STUB1/CALR/HSPA1L/NFE2L2/EIF2AK2/YOD1/CTDSP2/HSP90B1/HSPA4/GFPT1/BFAR/TBL2/DNAJA1/HYOU1/HSP90AB1/PPP2R5B/YIF1A/OPTN/VCP/MANF/MBTPS2/ERN1/BAK1/MBTPS1/EDEM3/PREB/DAXX/ARFGAP1/HSPB3/HDGF/ATF6B	85
BP	GO:0051653	spindle localization	28/7096	48/18670	0.003352	0.02756	0.02055	SPIRE1/SPDL1/ACTR2/MAP4/UBXN2B/PAFAH1B1/CDK5RAP2/CCDC155/SAPCD2/NSFL1C/ARHGEF2/ESPL1/ASPM/MYH9/BCCIP/NDC80/NDEL1/NUSAP1/ZW10/SPRY1/ACTR3/MOS/GPSM2/SPRY2/LLGL1/CENPA/MISP/KPNB1	28
BP	GO:0042278	purine nucleoside metabolic process	41/7096	76/18670	0.003366	0.02764	0.0206	PNP/GNAI3/ACPP/AHCY/RAN/AK3/NFS1/MPP1/HDDC3/GMPS/DGUOK/RAB23/APIP/ADK/MBIP/GUK1/IMPDH1/MTRR/ENOPH1/MOCS2/MACROD1/PRTFDC1/LRRK2/NME3/MTAP/NME4/GTPBP1/GMPR2/RHOQ/NME1/GAMT/MOCS3/ADA/AHCYL2/AHCYL1/RHOA/ENPP4/AMPD3/ADAL/GIMAP7/OARD1	41
BP	GO:0000075	cell cycle checkpoint	102/7096	216/18670	0.003388	0.02776	0.0207	PEA15/DUSP1/CDKN1A/MAD2L2/FBXO6/DYNC1LI1/RNASEH2B/RGCC/HUS1B/NABP1/SPDL1/GIGYF2/BTG2/DOT1L/RAD1/TGFB1/TAOK3/ZNF830/FEM1B/ETAA1/USP28/UIMC1/INTS7/SYF2/SETMAR/CDKN2B/PLK2/SFN/KLHL22/HRAS/CDK5RAP2/DONSON/PML/NSUN2/TIPIN/CCND1/RHNO1/ZNF207/LCMT1/ATM/TNKS1BP1/BUB3/MUC1/PLK3/RAD17/NDC80/PCNA/BAX/ZWILCH/CRADD/CASP2/RFWD3/CDKN1B/MAD2L1BP/TOP2B/CNOT4/PLAGL1/GEN1/ARID3A/ZW10/INTS3/TIMELESS/FOXO4/TICRR/THOC5/DTL/CEP63/FBXO4/E2F4/BRCA1/CNOT7/GML/ATR/CLOCK/MDM2/CLSPN/WEE1/RPL24/RBL2/RAD9A/TOPBP1/CDC20/PCID2/RB1/CNOT10/PRPF19/CARM1/EIF2AK4/HINFP/TRIAP1/AURKA/BRSK1/SOX4/BRCC3/WDR76/IK/PRMT1/CHFR/ZFYVE19/HORMAD1/E2F8/TOP2A	102
BP	GO:0009200	deoxyribonucleoside triphosphate metabolic process	13/7096	18/18670	0.003398	0.02776	0.0207	DGUOK/NUDT1/ADK/GUK1/SAMHD1/CMPK2/TYMS/ADA/TBPL1/RRM2B/DCTPP1/DUT/NUDT16	13
BP	GO:0031293	membrane protein intracellular domain proteolysis	13/7096	18/18670	0.003398	0.02776	0.0207	APH1B/PSENEN/NFKB1/RELA/TGFB1/TRAF6/SPPL2A/PSEN2/ADAM17/PSEN1/MBTPS2/APH1A/MBTPS1	13
BP	GO:0090026	positive regulation of monocyte chemotaxis	13/7096	18/18670	0.003398	0.02776	0.0207	FPR2/CCR2/LGMN/PLA2G7/CXCL10/CXCL12/AIF1/CCL5/HMGB1/MOSPD2/SERPINE1/CREB3/S100A14	13
BP	GO:0008585	female gonad development	50/7096	96/18670	0.003409	0.02782	0.02074	SOD1/RETN/PLEKHA1/KITLG/LFNG/CEBPB/NUPR1/UBE3A/ARRB1/CTNNA1/SGPL1/ZNF830/LEP/INSR/PTX3/EIF2B5/HSPA5/VEGFA/CASP3/IDH1/SIRT1/ATM/IMMP2L/BCL2/BAX/TIPARP/CASP2/NUP107/INHBA/HYAL3/MMP14/FZD4/SLIT2/CCDC182/FANCG/TAF4/FSHR/INHA/KMT2B/FANCA/ZFP42/EIF2B2/NRIP1/BMPR1B/AMHR2/MMP19/WT1/FOXO3/LHX9/SLIT3	50
BP	GO:1903305	regulation of regulated secretory pathway	78/7096	160/18670	0.003485	0.02826	0.02107	ITGAM/CCR2/APBA1/RAC2/LYN/RAP1B/SYT11/IL4R/LAMP1/HMOX1/C12orf4/GSK3B/MICAL1/STXBP1/UNC13B/PTAFR/STXBP2/HLA-F/FBXL20/FGR/ABR/CDK5/RAB3GAP1/DTNBP1/RAP1A/DOC2B/PREPL/LRRK2/SYT6/ADCY1/BCR/ARF1/P2RX1/ADORA2B/RPH3AL/VPS18/NAPA/GNAI2/UNC13D/RAB5A/CD300A/LGALS9/HYAL3/FER/RABGEF1/CAMK2A/CHRM2/DNM1L/CHRNA4/CDK5R2/SYT13/ATP2A2/DVL1/AP1G1/FMR1/IL13RA2/RAB3A/CHRNB2/P2RY4/PRAM1/SYT9/CD84/SYT1/SNX4/SYT2/VAMP1/STXBP3/DOC2A/SYT4/SYT5/SCAMP5/RAB3D/RIMS2/FOXF1/WNT7A/CACNA1H/RAB27A/P2RY1	78
BP	GO:0006221	pyrimidine nucleotide biosynthetic process	27/7096	46/18670	0.003494	0.02826	0.02107	CDS1/UPP1/GPAM/CDS2/CDADC1/CTPS2/AGPAT3/CMPK1/CMPK2/AGPAT4/NME3/NME4/NME1/PRPS1/TYMS/SHMT1/UCK1/TBPL1/AGPAT5/DCTD/CTPS1/CAD/AGPAT1/UCKL1/UPP2/DUT/AGPAT2	27
BP	GO:0006984	ER-nucleus signaling pathway	27/7096	46/18670	0.003494	0.02826	0.02107	PTPN2/PPP1R15A/FBXW7/GSK3B/ARHGEF10L/ATF4/WFS1/ERLIN1/ZBTB7B/HSPA5/NCK1/TMEM33/ERLIN2/PPP1R15B/EIF2S1/BCL2L11/SCAP/ASNS/CALR/NFE2L2/INSIG1/ATP2A2/HSP90B1/EIF2A/MBTPS2/MBTPS1/ATF6B	27
BP	GO:0032480	negative regulation of type I interferon production	27/7096	46/18670	0.003494	0.02826	0.02107	TNFAIP3/NLRC5/LILRB1/REL/NMI/DDX58/CACTIN/UBE2L6/RELB/ISG15/MAVS/CYLD/NPLOC4/IFIH1/OTUD5/YY1/PCBP2/GPATCH3/TAX1BP1/HERC5/HAVCR2/PIN1/NLRX1/TRAF3IP1/RNF216/NLRC3/RNF135	27
BP	GO:0043300	regulation of leukocyte degranulation	27/7096	46/18670	0.003494	0.02826	0.02107	ITGAM/CCR2/RAC2/LYN/IL4R/LAMP1/HMOX1/C12orf4/STXBP1/PTAFR/STXBP2/HLA-F/FGR/ABR/BCR/ADORA2B/UNC13D/CD300A/LGALS9/FER/RABGEF1/AP1G1/IL13RA2/PRAM1/CD84/SNX4/FOXF1	27
BP	GO:0071675	regulation of mononuclear cell migration	27/7096	46/18670	0.003494	0.02826	0.02107	FPR2/CCR2/DUSP1/LYN/LGMN/PLA2G7/TNF/CXCL10/CXCL12/TGFB1/CMKLR1/AIF1/AGER/CCL5/HMGB1/C3AR1/MOSPD2/BMP5/SERPINE1/CREB3/PLCB1/SLIT2/TRPV4/GREM1/SLAMF8/PDGFD/S100A14	27
BP	GO:1990928	response to amino acid starvation	27/7096	46/18670	0.003494	0.02826	0.02107	CDKN1A/FAS/ATF4/WDR24/MAP1LC3A/SEH1L/RRAGD/NPRL3/EIF2S1/KPTN/MAPK8/MAP3K5/RRAGA/IMPACT/EIF2AK2/ITFG2/SESN1/MAPK1/SH3GLB1/NPRL2/DAP/EIF2A/DAPL1/EIF2AK4/MTOR/DEPDC5/SESN2	27
BP	GO:0051054	positive regulation of DNA metabolic process	107/7096	228/18670	0.003502	0.02829	0.02109	KLF4/MAD2L2/PARP9/STAT6/EYA3/CD40/CEBPG/MYC/RGCC/PTPRC/UBE2N/ZNF304/SPIRE1/ERCC6/MAP3K4/ACTR2/ANXA3/TGFB1/HGF/MORC2/PTK2B/PRKCD/PKIB/UIMC1/TMEM161A/NAF1/DBF4B/SETMAR/HNRNPA1/USP9X/HRAS/HNRNPA2B1/DSCC1/XRCC5/DHX9/PML/HMGB1/SMCHD1/SIRT1/RAC1/IL6/PDGFB/PPARGC1A/RFC3/PTGES3/OTUD4/ATM/DTX3L/MAPKAPK5/HDAC10/PARM1/MLH1/PRKD2/PCNA/DNMT3L/XRCC1/PARP3/BAX/ERCC1/FUS/CLCF1/SETDB1/ST20/TIMELESS/HNRNPD/CCT4/KDM4D/CACYBP/FBXO4/CCT8/BRCA1/EGFR/ATR/USP7/TFRC/TNFSF4/MAPK1/RTEL1/ACD/EYA4/MAP2K4/ERCC2/CTC1/EXOSC3/HSP90AB1/TBX21/PRKCQ/APLF/POT1/EXOSC6/BRCC3/MGMT/WAS/PAXIP1/NUDT16/ATAD5/UBE2B/ENDOG/GNL3/GREM1/PNKP/SPIDR/WT1/NEK7/GRHL2/E2F8/ERCC8	107
BP	GO:0006367	transcription initiation from RNA polymerase II promoter	90/7096	188/18670	0.003512	0.02833	0.02112	VDR/CDKN1A/NR4A2/NOTCH2/RBPJ/DR1/THRA/PPARD/CBFB/MED10/KAT2B/THRAP3/NOTCH3/CDK4/ZNF451/NR3C2/NR1H2/SRF/GTF2E1/PPM1D/CCNH/TAF11/PSMC4/MED15/NR1D2/TAF12/GTF2F2/POLR2L/HMGB1/SUB1/MED17/CREB1/MED27/CCND1/CDK9/TAF5/PPARGC1A/POLR2H/MED16/GTF2H4/MED13/PSMC3/RXRA/CAND1/BAX/PSMC6/NR2E3/NR1H3/GTF2F1/MED4/TEAD2/POLR2F/MED30/POLR2D/TAF6L/MED25/PPARA/HEY2/GTF2A1/POLR2K/NOTCH4/ERCC2/TAF9B/CCNC/HNF1B/TAF4/RORA/HNF1A/NR4A3/MED8/MAZ/NR2F1/PSMC5/NRBP1/ESRRB/PSMC2/NR2E1/MED24/TBP/MED26/NRBF2/NR2C2/PAXIP1/POLR2I/WNT10B/NR2C2AP/NR1H4/NR2F6/TAF7/GTF2I	90
BP	GO:0045682	regulation of epidermis development	45/7096	85/18670	0.003548	0.02855	0.02129	VDR/DLL1/ZFP36/WNT5A/PPARD/KEAP1/CBFB/CTSK/TNF/EZH2/TRIM16/NCOA3/SFN/NAB1/PTCH2/SFRP4/TRADD/KRT36/KLF7/ALOX15B/HPSE/MAFG/BMP4/SRSF6/KRT10/CTSV/HES1/CDSN/AQP3/HEY2/CYP27B1/REG3G/TMEM79/CDH3/FOXN1/KRT84/ROCK2/WNT10B/SMO/HOXA7/PTCH1/GRHL2/MYCL/GRHL1/CD109	45
BP	GO:2001057	reactive nitrogen species metabolic process	45/7096	85/18670	0.003548	0.02855	0.02129	KLF4/NQO1/KLF2/CX3CR1/TLR2/ATP2B4/ACP5/GCH1/CLEC7A/POR/ARG2/PTGS2/JAK2/TNF/DDAH2/PKD2/TICAM1/CYP1B1/CD36/PTK2B/INSR/HBB/PTX3/TLR4/IL1B/AIF1/CLU/RAC1/GLA/SPR/DNM2/SUOX/CD47/AGXT2/RORA/IFNG/SLC7A2/CD34/HSP90AB1/WDR35/MARC2/MTOR/ROCK2/TLR6/GCHFR	45
BP	GO:0050710	negative regulation of cytokine secretion	40/7096	74/18670	0.00358	0.02877	0.02145	FN1/EZR/PTGER4/IL27RA/ANXA1/IL1R2/GBP1/ARG2/SYT11/LILRA5/NLRP3/TNFAIP3/BANK1/LGR4/NLRP12/RGCC/TNF/TNFRSF21/LILRB1/SERPINB1/MAPKBP1/PTPN22/PML/CD200R1/FFAR4/RABGEF1/BTN2A2/CPTP/PPP1R11/TLR8/SRGN/APOA1/TNFRSF4/CD34/C5AR2/CX3CL1/NR1H4/TLR6/C1QTNF3/GHRL	40
BP	GO:0030225	macrophage differentiation	26/7096	44/18670	0.003634	0.02917	0.02175	TLR2/SPI1/PTPN2/IL15/HCLS1/TGFB1/ROR2/CEBPA/VEGFA/CASP8/SIRT1/GAB3/MMP9/BMP4/ID2/INHBA/FADD/EIF2AK1/C1QC/CD4/RB1/INHA/CSF1R/APP/TSPAN2/PRKCA	26
BP	GO:0034113	heterotypic cell-cell adhesion	34/7096	61/18670	0.003643	0.02917	0.02175	KLF4/MYADM/LILRB2/ITGA5/CD58/ITGB7/MBP/CD2/FLOT1/CD44/PTPRC/TNF/ITGAD/MAPK7/ITGA4/ITGA7/IZUMO1/IL1B/AGER/IL1RN/BMP7/LCK/CD200R1/CTNNA3/CD47/MADCAM1/CD1D/DSC2/APOA1/PKP2/SKAP1/GCNT2/MAP2K5/GLDN	34
BP	GO:1903902	positive regulation of viral life cycle	34/7096	61/18670	0.003643	0.02917	0.02175	CD74/VPS37B/CHMP4B/STAU1/DDB1/ADARB1/CCL5/SRPK2/VAPB/TRIM11/DDX3X/TRIM21/TARBP2/TBC1D20/CHMP2A/TSG101/TOP2B/LGALS1/LGALS9/IFIT1/SRPK1/VPS4B/CNOT7/PKN2/ANXA2P2/FMR1/SMC3/CD4/PC/ANXA2/ADAR/PPIB/NUCKS1/TOP2A	34
BP	GO:0007018	microtubule-based movement	130/7096	283/18670	0.003653	0.02919	0.02176	APBA1/SUN2/MAP1S/SOD1/BLOC1S2/KLC1/DYNC1LI1/UCHL1/LRRC6/IFT172/LAMP1/TNPO1/IFT57/ACTR2/KIF9/KIF3B/KIFAP3/HIF1A/MAP4/HSPB1/PCM1/DYNLL2/SPA17/CEP131/CATSPER1/CENPE/BICD2/DPCD/IFT80/AP3M2/KIFC3/TRAK2/PURA/PAFAH1B1/DTNBP1/CLN3/RHOT2/WDR19/RASGRP1/BLOC1S6/KIF4A/BBS2/BBS12/RFX3/SFPQ/MKKS/IFT46/KIF2A/RPGR/IFT52/FLOT2/BICD1/KIF16B/WDR66/BBS4/SYNE2/ARL8A/MAK/HSPB11/TMEM201/BLOC1S3/COPG2/DNAI2/KIF24/DNAH17/KIF20B/DYNC2LI1/NDEL1/RSPH9/KTN1/KIF13A/CCDC151/DYNLRB1/CCDC65/DYNLRB2/ACTR3/BLOC1S1/BLOC1S4/KIF27/LCA5/PEX14/DNAL4/AP3B1/RSPH6A/PIH1D3/MAP1A/FMR1/DLGAP5/IFT20/TTLL1/DNAI1/KIF2C/KIF17/WDR60/KATNB1/IGBP1/KIF1B/AP3M1/MAATS1/KIF5B/TRAK1/IFT22/WDR35/DYNC1LI2/KLC2/TRAF3IP1/PRKCZ/DNAH10/MREG/KIF1C/TEKT3/APP/KIF12/IFT74/CCDC63/KPNB1/TRIM58/SPAG17/UXT/KLC3/DNAH8/TTLL6/TTC30B/MGARP/DNAH2/IFT81/KIF14/GAS8/ARL8B/TRIM46	130
BP	GO:0034284	response to monosaccharide	98/7096	207/18670	0.003654	0.02919	0.02176	SLC8A1/NAMPT/TRA2B/LDHA/ACVR2B/ATG7/GCLM/TXNIP/PTGS2/PPARD/SMAD2/ENY2/GSTP1/EGR1/HMGCR/LRP5/TGFB1/PPP3CB/SIN3A/AACS/UNC13B/FIS1/ARRB1/HIF1A/PIM3/PTK2B/PCK2/LEP/SRF/EIF2B5/IGF1R/CAT/CASP3/GCLC/AGER/C2CD2L/RAP1A/MPC2/LRP1/RAF1/TRPM4/RAC1/IRS2/ZNF236/PPARGC1A/KLF7/SPARC/SRI/OXCT1/POLG/KHK/GPR27/CDKN1B/NME1/RMI1/PRKACA/LGALS1/ITGA2/CTSV/PDX1/CYBA/PTPRN2/PFKFB2/HMGN3/CMA1/GIPR/PRKAA1/TCF7L2/COL4A3/BAD/PLA2G6/EIF2B1/HNF1B/KIF5B/EIF2B3/MEN1/WDR35/ZBTB20/NDUFAF2/MAP4K4/RHOA/ERN1/SLC9B2/SOX4/SIDT2/GCG/EIF2B2/PFKL/ENDOG/GJA1/NR1H4/STXBP4/SESN2/UCN3/FOXO3/GHRL/MIR146A/PHPT1	98
BP	GO:0006490	oligosaccharide-lipid intermediate biosynthetic process	14/7096	20/18670	0.003737	0.02974	0.02217	ALG2/ALG6/DOLK/ALG12/ALG10/DOLPP1/ALG13/NUS1/DHDDS/SRD5A3/ALG14/DPAGT1/ALG8/ALG3	14
BP	GO:0009264	deoxyribonucleotide catabolic process	14/7096	20/18670	0.003737	0.02974	0.02217	NEIL2/UNG/NUDT1/NT5C/SAMHD1/TDG/DERA/ADA/DCTPP1/NT5M/DUT/NUDT16/MBD4/SMUG1	14
BP	GO:0039529	RIG-I signaling pathway	14/7096	20/18670	0.003737	0.02974	0.02217	BIRC2/DDX60/DDX58/LSM14A/PUM2/NPLOC4/SEC14L1/ANKRD17/BIRC3/C1QBP/GPATCH3/TRIM15/NLRX1/ZCCHC3	14
BP	GO:0051099	positive regulation of binding	86/7096	179/18670	0.003759	0.02981	0.02222	KLF4/IGF1/S100A10/ARF6/STMN1/SKI/PPP2CA/PARP9/WNT5A/DPH3/DDRGK1/CEBPG/LFNG/FLOT1/JAK2/CTBP2/HFE/RAN/APOE/GSK3B/GMNN/TICAM1/TGFB1/ARRB1/RAPGEF2/SYAP1/TRAF6/BMP2/CDK5/PLK2/ABL1/DHX9/MAPRE1/LRP1/HMGB1/EIF2S1/GPSM1/CDK9/LRRK2/PLAUR/DTX3L/MARK3/NRP1/MMP9/PLXND1/PLCL1/BMP4/HMGB2/NME1/ITGA2/DERL1/PDX1/CLN5/HES1/KDM4D/MED25/TXN/TRAF2/ANXA2P2/PSEN1/FMR1/TCF7L2/ACD/CTHRC1/EPB41/ERCC2/EIF4G1/PLCL2/IFNG/SPTA1/GNL3L/PIN1/HSP90AB1/RB1/MEN1/EDF1/TERT/TRIM6/ANXA2/APP/MET/TIRAP/HOXA3/TRAF4/GCG/MEF2C	86
BP	GO:2001235	positive regulation of apoptotic signaling pathway	86/7096	179/18670	0.003759	0.02981	0.02222	SRPX/S100A9/S100A8/PEA15/BMF/SKIL/BCL10/PINK1/SOD1/PTPN2/PMAIP1/SIAH1/FBXW7/CTSC/YWHAH/JAK2/PTPRC/FAS/MAGED1/BCAP31/NUPR1/PDIA3/GSK3B/FIS1/CTNNA1/PRKCD/HYAL2/TFAP4/MCL1/HTRA2/TPD52L1/NCK1/TNFRSF12A/SFN/TNFSF10/CASP8/PAK2/DEDD2/PML/CHCHD10/RBCK1/SIRT1/SFPQ/LCK/G0S2/CYLD/PLAUR/FLCN/PDCD5/PRR7/WWOX/BCL2L11/SERINC3/MAPK8/NACC2/MMP9/BCL2/BAX/CRADD/CASP2/GZMB/INHBA/MLLT11/LGALS9/YWHAQ/DNM1L/PPP1CA/PPP2R1B/FADD/TRAF2/YWHAE/BAD/PLA2G6/BCLAF1/ST18/RAD9A/PPP1R13B/MOAP1/RET/ZSWIM2/WDR35/YWHAG/MSX1/BAK1/BMPR1B/MAPK9	86
BP	GO:0021543	pallium development	83/7096	172/18670	0.00376	0.02981	0.02222	ATP2B4/TRA2B/SUN2/TSC1/SRD5A1/FLNA/MBOAT7/BCL2A1/ALK/EZH2/BTBD3/GSK3B/ZEB2/BTG2/ANXA3/CSNK2A2/LRP8/HIF1A/PHACTR1/SRF/XRN2/FBXO45/EIF2B5/CDK5/CASP3/PAFAH1B1/SRGAP2C/P2RY12/LRP1/BBS2/CRK/MKKS/ASPM/ARX/BBS4/DIXDC1/SYNE2/SRGAP2/MFSD2A/DCLK2/NRP1/DISC1/TRAPPC9/ATIC/XRCC1/BAX/NRP2/NME1/PEX13/NDEL1/DAB1/BCAN/UQCRQ/KDM6B/CDK5R2/PLCB1/EGFR/SLIT2/PSEN1/YWHAE/BAD/HTR5A/PLXNA3/NR4A3/KIF5B/TMEM14B/EIF2B3/GNG12/PHLPP2/NR2E1/RELN/CEP120/RHOA/RTN4/PAX5/EFHC1/EZH1/LMX1A/FGF13/SMO/LHX6/KIF14/NTRK2	83
BP	GO:0044088	regulation of vacuole organization	25/7096	42/18670	0.003769	0.02985	0.02225	GRN/PINK1/C9orf72/FEZ2/SEC22B/NUPR1/CHMP4B/RAB3GAP1/NPRL3/LRRK2/PHF23/UBQLN2/RAB5A/LAPTM4B/ULK1/ANXA2P2/MTMR3/SH3GLB1/IFT20/SMCR8/NPRL2/SCFD1/RNF5/VPS16/ANXA2	25
BP	GO:0006405	RNA export from nucleus	67/7096	135/18670	0.003788	0.02996	0.02234	TSC1/NXF1/SRSF5/NUP62/NUP160/CHTOP/NUP214/ENY2/AGFG1/KHDRBS1/RAN/ALYREF/RNPS1/EIF6/MAGOHB/SARNP/NUP85/NXT1/SEH1L/YTHDC1/NUP43/HNRNPA1/NPM1/HNRNPA2B1/RBM8A/FYTTD1/DDX19B/DHX9/U2AF1/POM121/ZNF593/SRSF3/SYMPK/XPOT/CPSF3/RBM27/FIP1L1/NUP88/THOC2/SRSF6/SRSF7/NUP107/CDC40/THOC5/POLR2D/U2AF1L4/EIF5A/NUP93/LTV1/THOC6/RIOK2/SSB/SRRM1/NUP205/PHAX/SRSF4/EIF4E/NUP50/DHX38/MCM3AP/PCID2/CPSF2/CPSF1/RRS1/POM121C/AAAS/UPF1	67
BP	GO:0002532	production of molecular mediator involved in inflammatory response	39/7096	72/18670	0.003806	0.03003	0.02239	MYD88/NOD2/ALOX5/IL1R2/CLEC7A/APPL2/GRN/LYN/IL17RA/DUSP10/IL4R/GBP5/TICAM1/CHID1/CD36/SEH1L/LEP/TLR4/IDO1/C5orf30/ADCY7/RPS19/CD96/P2RX1/GPSM3/MEFV/SERPINE1/IL17B/BAP1/SLC7A2/SNX4/LBP/PDCD4/ABCD1/APPL1/NLRC3/SLAMF8/TLR6/IL17RC	39
BP	GO:0032024	positive regulation of insulin secretion	39/7096	72/18670	0.003806	0.03003	0.02239	PPARD/JAK2/PPP3CB/AACS/ARRB1/HIF1A/MCU/C2CD2L/MPC2/LRP1/TRPM4/DOC2B/RAC1/GLUD1/IRS2/SERP1/SRI/OXCT1/RPH3AL/GPR27/PDX1/TM7SF3/PFKFB2/GIPR/TCF7L2/BAD/PLA2G6/KIF5B/SOX4/GCG/NLGN2/GJA1/NR1H4/TARDBP/UCN3/RBP4/PSMD9/GHRL/PHPT1	39
BP	GO:0045071	negative regulation of viral genome replication	33/7096	59/18670	0.003851	0.03034	0.02262	PLSCR1/OASL/IFITM2/TNF/IFITM1/IFITM3/MORC2/ISG20/OAS3/RSAD2/CCL5/SRPK2/ISG15/APOBEC3G/MAVS/APOBEC3C/IFIT5/ILF3/BANF1/ZC3HAV1/CCL8/TNIP1/INPP5K/CCNK/MX1/SETDB1/RNASEL/IFIT1/SRPK1/EIF2AK2/TRIM6/EIF2AK4/BTBD17	33
BP	GO:0010976	positive regulation of neuron projection development	129/7096	281/18670	0.003876	0.03049	0.02273	S100A9/FN1/FYN/DPYSL3/SKIL/GRN/LYN/WNT5A/RAB11A/CAMK1D/MAP2K1/RGS2/ALK/DVL2/EZH2/ARHGDIA/APOE/ZEB2/ACTR2/PLAA/CXCL12/PLXNB2/LRP8/TWF2/ARSB/HGF/PAK1/RAPGEF2/MEGF8/SS18L2/PTK2B/PLXNC1/SRF/SCN1B/BAIAP2/ITSN1/HSPA5/NCK1/FIG4/VEGFA/TNFRSF12A/PAFAH1B1/GDI1/GRIP1/CREB3L2/FBXO38/PTK6/RAP1A/SEMA4D/ANKRD27/LRP1/NPTN/BMP7/TMEM106B/CAPRIN1/KALRN/CYFIP1/CRTC1/ARF1/SETX/PLXNA1/BMP5/NRP1/DISC1/PLXND1/AVIL/L1CAM/MARK2/NME1/LPAR3/IST1/NDEL1/MOB2/SHANK1/CPEB3/SEMA5A/ITGA3/LPAR1/BHLHB9/DNM1L/AP2A1/FZD1/NFE2L2/CNTF/MUL1/AMIGO1/ABL2/SS18L1/FZD4/ITSN2/SLIT2/LRRC7/DVL1/PSEN1/FMR1/GPC2/SHOX2/KATNB1/RASAL1/MAP3K13/RUFY3/PLXNA3/SYT1/RET/TRAK1/CPNE9/TMEM30A/IL1RAPL1/PPP2R5B/PLXNA2/SYT2/SYT4/RELN/MTOR/CHODL/RHOA/C21orf91/CX3CL1/PARP6/CRABP2/RIMS2/SHANK3/MACF1/CNTN1/TRPV2/ZMYND8/NTRK2/CAMK2B/BMPR2	129
BP	GO:0090175	regulation of establishment of planar polarity	56/7096	110/18670	0.003878	0.03049	0.02273	WNT5A/CELSR2/PSMB9/PSMB8/PSMA5/DVL2/PSMD11/PSME1/DAAM1/PFN1/PSMB10/PSMA1/PSMA4/ROR2/ABL1/PSMB1/SAPCD2/PSMC4/PSMD13/PSMB3/RAC1/PSMB5/PSMD6/PSMC3/AP2A2/PSME3/PSMC6/ROR1/AP2S1/MKS1/FZD5/AP2A1/FZD1/FZD4/DVL1/WNT1/CTHRC1/PSMC1/PSMD8/PSMA2/ANKRD6/FZD7/PSMC5/PSMC2/AP2M1/GPC4/PSMB2/PSMD4/RHOA/FZD2/GRHL3/PSMD1/WNT7A/PSMB4/PSMD9/PSMD3	56
BP	GO:0016073	snRNA metabolic process	52/7096	101/18670	0.003913	0.03062	0.02282	MEPCE/ELL2/NABP1/SNAPC3/POU2F1/POU2F2/INTS5/GTF2E1/INTS7/TOE1/TAF11/GTF2F2/INTS9/POLR2L/SNAPC1/USB1/SNAPC2/ELL3/CDK9/TAF5/RPRD1B/INTS8/POLR2H/NHP2/RPRD2/EXOSC2/CCNK/USPL1/GTF2F1/INTS3/EXOSC7/POLR2F/POLR2D/INTS2/GTF2A1/POLR2K/PHAX/EXOSC9/RPAP2/EXOSC3/TBP/CCNT1/EXOSC6/EXOSC8/SNAPC4/SRRT/INTS4/ICE1/NOP10/POLR2I/INTS6/EXOSC5	52
BP	GO:0018107	peptidyl-threonine phosphorylation	63/7096	126/18670	0.003937	0.03062	0.02282	OXSR1/WNT5A/AZU1/SMAD7/MAP2K1/CSNK1G2/DYRK4/VRK2/GSK3B/DYRK2/CSNK2A2/UBE2K/TGFB1/CSNK1D/PRKCD/DYRK1B/CDK5/NLK/MAP3K12/CSNK2B/BMP7/CHI3L1/TTBK1/ACVR1B/LRRK2/TNKS1BP1/CSNK1A1/CSNK1E/SPHK1/PRKAG2/MAPK8/BCL2/PRKD2/INPP5K/MARK2/PRKACA/CSNK1G3/DDIT4/HIPK1/CAMK2A/DMTN/SPRED1/DYRK3/CAMK2D/CEMIP/ULK1/SPRY2/MAPK1/VRK1/EIF4G1/PPEF2/CAD/LMTK2/HIPK3/TRIM6/MTOR/CLK1/APP/TTBK2/GCG/ROCK2/CSNK1G1/PRKCA	63
BP	GO:0006048	UDP-N-acetylglucosamine biosynthetic process	9/7096	11/18670	0.003942	0.03062	0.02282	PGM3/GNPDA1/UAP1/NAGK/RENBP/GNPNAT1/UAP1L1/GFPT1/GFPT2	9
BP	GO:0008655	pyrimidine-containing compound salvage	9/7096	11/18670	0.003942	0.03062	0.02282	TYMP/UPP1/TK1/DCK/UCK1/TK2/CDA/UCKL1/UPP2	9
BP	GO:0032490	detection of molecule of bacterial origin	9/7096	11/18670	0.003942	0.03062	0.02282	NOD2/TLR1/TLR2/LY96/SCARB1/TLR4/TREM2/LBP/TLR6	9
BP	GO:0043097	pyrimidine nucleoside salvage	9/7096	11/18670	0.003942	0.03062	0.02282	TYMP/UPP1/TK1/DCK/UCK1/TK2/CDA/UCKL1/UPP2	9
BP	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress	9/7096	11/18670	0.003942	0.03062	0.02282	EPAS1/HMOX1/ATF4/SIN3A/HIF1A/CHD6/ARNT/NFE2L2/SESN2	9
BP	GO:0045628	regulation of T-helper 2 cell differentiation	9/7096	11/18670	0.003942	0.03062	0.02282	ANXA1/BCL6/NLRP3/IL4R/SOCS5/HLX/IL18/TNFSF4/PRKCZ	9
BP	GO:0070106	interleukin-27-mediated signaling pathway	9/7096	11/18670	0.003942	0.03062	0.02282	IL27RA/STAT3/STAT1/JAK2/IL6ST/TYK2/EBI3/CANX/JAK1	9
BP	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	9/7096	11/18670	0.003942	0.03062	0.02282	JAK2/FAS/TFAP4/HTRA2/CASP8/PRR7/BAX/LGALS9/ST18	9
BP	GO:0030595	leukocyte chemotaxis	105/7096	224/18670	0.003967	0.03078	0.02294	S100A9/S100A8/FPR2/S100A12/CCR2/RAC2/DUSP1/ANXA1/BST1/LYN/OXSR1/WNT5A/AZU1/IL17RA/FLT1/VEGFB/CAMK1D/S1PR1/MIF/PPBP/LGMN/CXCL9/PLA2G7/CXCL11/ADAM8/CD74/CXCL10/CXCL12/PTPRO/MPP1/NUP85/FFAR2/PTK2B/SWAP70/CORO1A/CXCL13/VEGFA/PDE4B/CMKLR1/IL1B/AIF1/CCL5/HMGB1/TNFRSF11A/CCL7/IL1RN/TRPM4/TRPM2/RAC1/CXCR1/IL6/PDGFB/IL16/CCR5/CKLF/SLC12A2/RPS19/C3AR1/MOSPD2/CCL13/GPSM3/ZNF580/TMEM102/CCL8/SERPINE1/PIK3CD/CCR6/GPR18/CH25H/CREB3/LGALS9/CNR2/CALR/MST1/C1QBP/VAV1/CXCR2/ADAM17/CCL20/JAM3/PREX1/SLIT2/CCL26/CSF3R/C10orf99/PIK3CG/LBP/TRPV4/C5AR2/GPR183/DAPK2/CX3CL1/CXCR3/CCL19/TIRAP/CCL4/CCR7/GREM1/CCL24/SLAMF8/IL23A/IL17RC/CXCL6/S100A14/IL37	105
BP	GO:0032469	endoplasmic reticulum calcium ion homeostasis	15/7096	22/18670	0.003986	0.03084	0.02299	TMBIM6/BCAP31/KCTD17/ITPR1/FIS1/WFS1/PML/BCL2/TGM2/BAX/CAMK2D/ATP2A2/PSEN1/APP/BAK1	15
BP	GO:0048305	immunoglobulin secretion	15/7096	22/18670	0.003986	0.03084	0.02299	TMBIM6/CD40/TNF/CD22/POU2F2/TNFSF13B/TRAF6/HLA-E/GPI/IL6/LAX1/TRAF2/TNFSF4/TNFRSF4/RBP4	15
BP	GO:0006040	amino sugar metabolic process	23/7096	38/18670	0.004016	0.031	0.02311	NANP/PGM3/EXTL2/GNPDA1/NPL/UAP1/NAGK/CHST2/CSGALNACT1/RENBP/CHST5/CTBS/GNPNAT1/MGAT3/CMAS/SLC35A3/UAP1L1/GFPT1/ST3GAL1/GNE/GFPT2/DPAGT1/CHST7	23
BP	GO:0032350	regulation of hormone metabolic process	23/7096	38/18670	0.004016	0.031	0.02311	VDR/POR/ATP1A1/RDH10/EGR1/TNF/AKR1C3/NFKB1/HIF1A/BMP2/PAX8/IL1B/PPARGC1A/GNB3/BMP5/ZMPSTE24/ARNT/STUB1/TCF7L2/CYP27B1/IFNG/DUOXA1/HPN	23
BP	GO:0021766	hippocampus development	43/7096	81/18670	0.004034	0.03107	0.02316	ATP2B4/TSC1/SRD5A1/ALK/EZH2/GSK3B/ZEB2/BTG2/ANXA3/LRP8/SRF/XRN2/EIF2B5/CDK5/CASP3/PAFAH1B1/BBS2/CRK/MKKS/BBS4/MFSD2A/DCLK2/XRCC1/NME1/DAB1/BCAN/UQCRQ/KDM6B/CDK5R2/YWHAE/HTR5A/PLXNA3/NR4A3/KIF5B/EIF2B3/PHLPP2/NR2E1/RELN/EZH1/LMX1A/FGF13/SMO/KIF14	43
BP	GO:1902930	regulation of alcohol biosynthetic process	43/7096	81/18670	0.004034	0.03107	0.02316	VDR/POR/SOD1/NFYC/GPAM/SQLE/TNF/NFKB1/RAN/APOE/HMGCR/HMGCS1/PTAFR/SCD/PTK2B/ERLIN1/P2RY6/BMP2/IL1B/ERLIN2/FDPS/ACACB/FGF1/TM7SF2/IDI1/BMP5/SCAP/ABCG1/SC5D/PLEK/SREBF2/PRKAA1/CYP27B1/IFNG/MBTPS2/SNCA/ELOVL6/CD244/MBTPS1/KPNB1/ADCYAP1R1/P2RY1/NTSR1	43
BP	GO:0050766	positive regulation of phagocytosis	38/7096	70/18670	0.004047	0.03112	0.0232	FPR2/IL2RG/CLEC7A/APPL2/SLC11A1/AZU1/SOD1/LYAR/CAMK1D/PTPRC/IL15/TNF/RAB31/CD36/PTX3/IL2RB/ABR/IL1B/SIRPB1/RAP1A/CD300LF/LRP1/BCR/IL15RA/DNM2/CD47/ITGA2/CYBA/CALR/ABCA7/MERTK/APOA1/SIRPG/TREM2/IFNG/TULP1/RAB27A/PTPRJ	38
BP	GO:0042770	signal transduction in response to DNA damage	66/7096	133/18670	0.00405	0.03112	0.0232	CDKN1A/MAD2L2/PMAIP1/MIF/CD44/RGCC/BATF/CD74/BTG2/EEF1E1/PTTG1IP/UIMC1/TFAP4/PLK2/SFN/SP100/ABL1/PPM1D/PML/SIRT1/NDRG1/ATM/TNKS1BP1/MUC1/PLK3/KAT5/PCNA/BAX/CRADD/CASP2/CDKN1B/CNOT4/PLAGL1/GRB2/ARID3A/ZMPSTE24/DTL/CEP63/SPRED1/DYRK3/E2F4/BRCA1/CNOT7/GML/USP10/ATR/WNT1/MDM2/RBL2/SNAI1/ING4/CNOT10/PRPF19/CARM1/MSX1/TRIAP1/AURKA/SOX4/BRCC3/PAXIP1/PRMT1/ATAD5/SESN2/E2F8/HIC1/FOXO3	66
BP	GO:0097242	amyloid-beta clearance	22/7096	36/18670	0.004121	0.03163	0.02358	ITGAM/RAB11A/MARCO/TNF/APOE/HMGCR/CD36/LRPAP1/SRF/INSR/IGF1R/LDLR/LRP1/CLU/MIR34A/RAB5A/ABCA7/IFNGR1/TREM2/IFNG/LRP4/PICALM	22
BP	GO:0060071	Wnt signaling pathway, planar cell polarity pathway	55/7096	108/18670	0.004146	0.0317	0.02363	WNT5A/CELSR2/PSMB9/PSMB8/PSMA5/DVL2/PSMD11/PSME1/DAAM1/PFN1/PSMB10/PSMA1/PSMA4/ROR2/ABL1/PSMB1/PSMC4/PSMD13/PSMB3/RAC1/PSMB5/PSMD6/PSMC3/AP2A2/PSME3/PSMC6/ROR1/AP2S1/MKS1/FZD5/AP2A1/FZD1/FZD4/DVL1/WNT1/CTHRC1/PSMC1/PSMD8/PSMA2/ANKRD6/FZD7/PSMC5/PSMC2/AP2M1/GPC4/PSMB2/PSMD4/RHOA/FZD2/GRHL3/PSMD1/WNT7A/PSMB4/PSMD9/PSMD3	55
BP	GO:0046849	bone remodeling	47/7096	90/18670	0.004152	0.0317	0.02363	SIGLEC15/RAC2/PDK4/ACP5/NOTCH2/CSK/ATP6AP1/TPP1/SPP1/TNFAIP3/S1PR1/SNX10/LGR4/CTSK/P2RX7/ADAM8/LRP5/TGFB1/PTK2B/LEP/TRAF6/TCIRG1/LTBP3/MITF/TNFRSF11A/IL7/RAC1/PLEKHM1/IL6/TMEM64/ADRB2/SUCO/EGFR/TFRC/DCSTAMP/CTHRC1/TGFB3/CLDN18/CSF1R/RAB3D/IAPP/EFNA2/TMEM119/GJA1/GREM1/PRKCA/GDF5	47
BP	GO:0035588	G protein-coupled purinergic receptor signaling pathway	16/7096	24/18670	0.004155	0.0317	0.02363	P2RY14/ACPP/P2RY8/PTAFR/P2RY6/GPR171/P2RY12/GPR34/ADORA2B/GNAI2/P2RY13/ADA/P2RY4/P2RY10/ADORA3/P2RY1	16
BP	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway	16/7096	24/18670	0.004155	0.0317	0.02363	KCNN4/PTPRC/RELA/CD226/SLC39A10/TESPA1/RAB29/LCK/CYLD/TRAT1/PRKD2/ADA/NFAM1/FOXP1/CCR7/CMTM3	16
BP	GO:0051905	establishment of pigment granule localization	16/7096	24/18670	0.004155	0.0317	0.02363	BBS5/RAB11A/MLPH/MYO5A/ASIP/BLOC1S6/BBS2/MKKS/BBS4/BLOC1S3/DCTN2/BBS7/GPR143/MREG/CDH3/RAB27A	16
BP	GO:0070301	cellular response to hydrogen peroxide	51/7096	99/18670	0.004182	0.03187	0.02376	KLF4/NQO1/KLF2/ANXA1/PINK1/AIFM1/STAT6/PLEKHA1/TNFAIP3/PSAP/EZH2/RELA/AXL/CYP1B1/HGF/MAP1LC3A/MAPK7/PCGF2/PRKCD/MAPK13/NET1/ABL1/SIRT1/TRPM2/OSER1/IL6/LRRK2/ETS1/MIR34A/SETX/SPHK1/HDAC2/ZNF580/PCNA/MAP3K5/KDM6B/NFE2L2/IMPACT/TXN/PRKAA1/MDM2/NR4A3/IL18RAP/PDE8A/PDCD10/SIGMAR1/MET/ENDOG/PDGFD/FOXO3/ZNF277	51
BP	GO:0018196	peptidyl-asparagine modification	21/7096	34/18670	0.004208	0.03203	0.02388	MCFD2/MGAT2/DAD1/MGAT5/STT3A/OST4/UBE2J1/UBE2G2/DPM1/HIF1AN/RPN2/STT3B/NUDT14/ASGR2/LMAN1/TUSC3/DPM3/ASGR1/VCP/DDOST/ALG8	21
BP	GO:1990845	adaptive thermogenesis	75/7096	154/18670	0.004248	0.03221	0.02402	EPAS1/CCR2/ACOT13/APPL2/ACVR2B/RBPJ/FABP4/STAT6/THRA/HADH/PLAC8/ADIPOR1/ALDH1A1/ABHD6/LGR4/PER2/IL4R/CEBPB/JAK2/IL15/ZNF516/ATF4/CPT2/ARRDC3/IL18R1/IP6K1/SCD/CD36/LEP/NR1H2/SCTR/TLR4/ZBTB7B/DECR1/PDGFC/ADRB1/IGF1R/VEGFA/CMKLR1/OMA1/UCP2/GATM/TFE3/G0S2/PPARGC1A/FLCN/GRB10/PLCL1/FH/NR1H3/ADRB2/FFAR4/KSR2/KDM6B/UCP1/FABP5/IL18/ADAM17/ADIPOR2/PLCL2/ARNTL/OGT/RB1/DBH/TRPV4/MFAP2/ELOVL6/SLN/DIO2/WNT10B/GJA1/ALMS1/TRPV2/GHRL/PRKAB1	75
BP	GO:0006631	fatty acid metabolic process	171/7096	383/18670	0.004256	0.03221	0.02402	ALOX5/SLC27A1/PDK4/ALDH3A2/ANXA1/PRKAR2B/SLC27A3/ALOX5AP/APPL2/HADHB/POR/CBR4/GPAM/PTGS2/PPARD/HADH/ADIPOR1/ACAA1/MIF/SIRT4/PANK2/ACOT7/PTGR1/CRYL1/SLC45A3/PER2/ACSL5/PHYH/APOC1/GSTP1/ACSM5/MGLL/DEGS1/CD74/ELOVL5/SCP2/AKR1C3/LYPLA2/LPGAT1/PLAA/ALKBH7/ZADH2/PNPLA3/PTGR2/PDK2/ETFA/EIF6/CPT2/AACS/CYP1B1/MORC2/AUH/ABCD3/SGPL1/SCD/HPGD/CD36/MYO5A/PCK2/OXSM/LEP/NR1H2/ERLIN1/ECH1/ACADM/ACADS/CYP2J2/DECR1/ACSL4/FADS3/ACLY/CYP2S1/GSTZ1/MCEE/IL1B/AIG1/PLA2G15/ACOX1/ETFDH/TECR/ECI2/ERLIN2/SLC27A2/HSD17B4/AASDH/ACACB/CES2/GSTA1/ACOX2/ELOVL7/SIRT1/ACBD5/GPX4/DGAT2/ACADSB/FABP3/IRS2/BDH2/PPARGC1A/ABHD3/DECR2/ALDH5A1/MLYCD/APOA5/PNPLA8/PTGES3/CREM/ACSL6/MSMO1/ALOX15B/DAGLB/PLA2G3/PAM/PRKAG2/PCCB/CYP2D6/CYP1A2/ECI1/SCAP/NUDT19/THEM4/NR1H3/ETFB/PEX13/PDK1/TYSND1/CPT1A/EHHADH/HPGDS/ACADVL/GSTM4/HADHA/NFE2L1/INSIG1/PDP2/NUDT7/FABP5/BRCA1/PPARA/ACAA2/ADIPOR2/PRKAA1/GGT5/ACOX3/GNPAT/PRKAG1/NR4A3/PDP1/CROT/GPX1/MTOR/SNCA/ELOVL6/ATP6V1B1/CYP4F3/ABCD1/ABHD16A/PDPR/CYP2A6/PLP1/HACL1/ADH7/CYP2C8/SESN2/FADS2/PTGS1/HSD17B12/HAO1/CYP2U1/ACOT8/PRKAB1	171
BP	GO:0051875	pigment granule localization	17/7096	26/18670	0.004258	0.03221	0.02402	BBS5/RAB11A/MLPH/MYO5A/ASIP/VPS33A/BLOC1S6/BBS2/MKKS/BBS4/BLOC1S3/DCTN2/BBS7/GPR143/MREG/CDH3/RAB27A	17
BP	GO:0030041	actin filament polymerization	87/7096	182/18670	0.004263	0.03221	0.02402	MYADM/CDC42EP4/VASP/ARF6/DIAPH1/HCK/RHOBTB1/PLEKHG2/PSTPIP1/JAK2/TMSB10/SPIRE1/IQGAP2/ACTR2/TMOD3/HCLS1/GAS7/EVL/TWF2/RDX/PFN1/CDC42EP2/PTK2B/CAPZA2/PRKCD/LATS1/GMFG/CORO1A/BAIAP2/ARFGEF1/CAPG/NCK1/PSTPIP2/FCHSD1/AIF1/ARPC1A/CAPZA1/MKKS/RAC1/ARPIN/SPTBN1/ARPC1B/CDC42EP3/CYFIP1/MYO1C/CORO1B/ARHGAP6/BBS4/ARF1/ARPC5L/COTL1/AVIL/MICALL2/KANK1/TRIOBP/ARHGAP18/ADD3/TTC17/GRB2/JMY/ACTR3B/FER/DMTN/ACTR3/MSRB1/LMOD3/SCIN/PREX1/SLIT2/CCL26/ARPC4/SPTA1/SPTBN2/ARPC2/KANK3/MTOR/RHOA/PICK1/SNX9/CCR7/WAS/RHOBTB2/CCL24/BIN1/NCKAP1/FCHSD2/FMN1	87
BP	GO:0035587	purinergic receptor signaling pathway	20/7096	32/18670	0.004273	0.03221	0.02402	P2RY14/ACPP/P2RY8/P2RX7/PTAFR/P2RY6/GPR171/P2RY12/GPR34/P2RX1/ADORA2B/GNAI2/P2RY13/ADA/P2RY4/P2RY10/P2RX2/ADORA3/P2RY1/P2RX5	20
BP	GO:1904467	regulation of tumor necrosis factor secretion	20/7096	32/18670	0.004273	0.03221	0.02402	IL27RA/WNT5A/ARG2/SYT11/LILRA5/LILRA2/FRMD8/DDX58/DHX9/MAVS/LRRK2/IFIH1/LGALS9/FZD5/IFNGR1/HAVCR2/IFNG/CX3CL1/NR1H4/GHRL	20
BP	GO:0120032	regulation of plasma membrane bounded cell projection assembly	84/7096	175/18670	0.00428	0.03221	0.02402	CDC42EP4/RAC2/DPYSL3/ARF6/ATG3/DNM3/ARAP1/KLHL41/P2RX7/KCTD17/PLD1/EVL/TWF2/PLEK2/RDX/PFN1/CDC42EP2/MAP4/PRKCD/SRF/RHOG/FUZ/HRAS/SRGAP2C/FAM98A/P2RY12/ATP8B1/PPP1R16B/TRPM2/RAC1/PLEKHM1/CCDC88A/CDC42EP3/CYLD/CYFIP1/ADAMTS16/SH3YL1/BBS4/SYNE2/MAK/NRP1/DNM2/WDPCP/BCAS3/HDAC4/RHOQ/RAB5A/KANK1/KLF5/DYNC2LI1/NDEL1/TBC1D7/FER/CCDC151/DMTN/CORO1C/RCC2/BIN3/DOCK11/SLIT2/FSCN1/WNT1/FMR1/TCHP/IFT20/MYO10/TGFB3/ATP7A/HRG/MIEN1/TACSTD2/ARPC2/EPS8L2/CEP120/VDAC3/MTOR/CCL19/CCR7/WAS/TENM2/RP1/NCKAP1/WRAP73/ZMYND8	84
BP	GO:0044380	protein localization to cytoskeleton	31/7096	55/18670	0.004292	0.03221	0.02402	KLHL21/NUP62/DIAPH1/SNX10/ABHD17C/GSK3B/GOLGB1/PCM1/CSNK1D/CEP131/UBXN2B/KIAA0753/NSFL1C/MAPRE1/SPAG5/MAPRE2/BICD1/BBS4/CHAMP1/DISC1/HOOK3/KIF20B/DCTN2/MID2/CRIPT/DVL1/MAP1A/CEP83/AURKA/TTBK2/C2CD3	31
BP	GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	18/7096	28/18670	0.004306	0.03221	0.02402	YME1L1/KLHL15/OMA1/UBE2W/CLPP/SDF2L1/TOR1A/RNF126/DERL1/NGLY1/STUB1/ATXN3/POMT2/RNF185/RNF5/FBXL17/VCP/ATXN3L	18
BP	GO:0002828	regulation of type 2 immune response	19/7096	30/18670	0.004308	0.03221	0.02402	NOD2/CCR2/IL27RA/ANXA1/ARG2/STAT6/BCL6/NLRP3/IL4R/CD74/SOCS5/RSAD2/IDO1/IL6/HLX/IL18/TNFSF4/PRKCZ/TBX21	19
BP	GO:0006517	protein deglycosylation	19/7096	30/18670	0.004308	0.03221	0.02402	RNF103/MAN1C1/RNF139/TRIM13/EDEM1/MAN2A2/MAN2B1/AGA/EDEM2/MAN1B1/NGLY1/DERL2/MAN1A2/RNF185/RNF5/ENGASE/EDEM3/MAN2B2/OS9	19
BP	GO:0032743	positive regulation of interleukin-2 production	19/7096	30/18670	0.004308	0.03221	0.02402	CCR2/ANXA1/CLEC7A/PTPRC/TRAF6/PDE4B/ABL1/IL1B/SPTBN1/GLMN/PRKD2/IL1A/TRAF2/CD4/CD80/PRKCQ/CD83/MALT1/CD3E	19
BP	GO:0046640	regulation of alpha-beta T cell proliferation	19/7096	30/18670	0.004308	0.03221	0.02402	CCR2/CD55/IRF1/ARG2/TNFRSF14/SH3RF1/PTPRC/ZBTB7B/HLA-E/RASAL3/CD274/LGALS9/EBI3/IL18/TNFSF4/IL12B/CD3E/TWSG1/IL23A	19
BP	GO:0050690	regulation of defense response to virus by virus	19/7096	30/18670	0.004308	0.03221	0.02402	FYN/HCK/AP1B1/PAK2/RAC1/LCK/AP1M2/ARF1/AP2A2/CD247/AP2S1/AP2A1/ELMO1/EIF2AK2/AP1S3/AP1G1/AP1M1/CD4/AP2M1	19
BP	GO:0090022	regulation of neutrophil chemotaxis	19/7096	30/18670	0.004308	0.03221	0.02402	RAC2/BST1/CAMK1D/CD74/MPP1/RAC1/C3AR1/MOSPD2/C1QBP/CXCR2/JAM3/SLIT2/LBP/C5AR2/DAPK2/CCL19/TIRAP/CCR7/IL23A	19
BP	GO:0072522	purine-containing compound biosynthetic process	142/7096	313/18670	0.004345	0.03246	0.0242	IGF1/PNP/CBFA2T3/HK3/PDK4/LDHA/PINK1/FBP1/PGK1/CBR4/VPS9D1/STAT3/PFKFB3/NUP62/NUP160/PFKM/PFKP/GAPDH/PANK2/NUP214/ACOT7/PAPSS1/ACSL5/SLC2A6/P2RX7/ELOVL5/NUPR1/AK3/PGAM1/AK2/PKM/PDK2/GALK1/EIF6/TPI1/ZBTB7A/TGFB1/GMPS/DGUOK/NUP85/HIF1A/SCD/SEH1L/PANK3/ADK/INSR/ALDOC/PRPSAP1/PANK1/GUK1/PAICS/NUP43/IMPDH1/ACSL4/ACLY/ENO1/DNAJC30/ALDOA/GSTZ1/TECR/POM121/MPC2/ACACB/OGDH/ELOVL7/GPI/ADCY7/PRTFDC1/PFKFB4/PPARGC1A/FLCN/MLYCD/ADCY1/DHTKD1/NME3/MTAP/ACSL6/SLC25A12/LDHC/NME4/PRKAG2/MYOG/NCOR1/ADORA2B/PFKFB1/GMPR2/ATIC/ADCY3/NUP88/HDAC4/PAPSS2/NME1/NUP107/PDK1/PRPS1/PPAT/PDHB/FOXK2/DDIT4/AMPD2/PGK2/PFKFB2/ADA/DCK/ARNT/DLAT/SHMT1/PDP2/PPARA/NUP93/SLC25A13/PRKAA1/PSEN1/PDHA2/NUP205/ENO2/PID1/GUCY2D/SLC4A1/PRPS1L1/TREM2/NUP50/IFNG/PRKAG1/OGT/PDP1/PRPS2/ESRRB/ZBTB20/VCP/ADPGK/TAZ/APP/SNCA/ELOVL6/AMPD3/ADAL/PDPR/PFKL/POM121C/AAAS/HSD17B12	142
BP	GO:0002286	T cell activation involved in immune response	54/7096	106/18670	0.004434	0.03308	0.02466	PTGER4/NFKBIZ/ANXA1/APBB1IP/SLC11A1/TSC1/CLEC4D/STAT6/STAT3/BCL6/NLRP3/CLEC4E/SMAD7/CD1C/FGL2/LY9/IL4R/BATF/LILRB1/IL18R1/SOCS5/ITGAL/SEMA4A/ZBTB7B/RELB/NFKBID/HLA-DMB/HMGB1/IL6/LCP1/IFNK/IL12RB1/LGALS9/HLX/IL18/TNFSF4/PSEN1/RORA/HAVCR2/IFNG/ATP7A/TNFSF18/IL12B/EIF2AK4/PRKCZ/CD80/TBX21/MTOR/FOXP1/GPR183/CCL19/MALT1/RAB27A/IL23A	54
BP	GO:0043255	regulation of carbohydrate biosynthetic process	50/7096	97/18670	0.00447	0.03332	0.02484	IGF1/FBP1/PTPN2/SIK1/NFKB1/GSK3B/KAT2B/PDK2/DYRK2/TGFB1/PTAFR/PTK2B/LEP/PPP1R3E/INSR/P2RY6/PPP1R3D/DDB1/SLC35B4/SIRT1/DGAT2/IRS2/PDGFB/PPARGC1A/NLN/INPP5K/PPP1R3B/PPP1R3F/PLEK/FOXK2/AP2A1/SERPINA12/PPP1CA/MST1/PPARA/KAT2A/OGT/PPP1CB/ESRRB/MTOR/SNCA/CD244/GCG/ADCYAP1R1/SESN2/C1QTNF3/WDR5/P2RY1/FAM3A/NTSR1	50
BP	GO:0034101	erythrocyte homeostasis	61/7096	122/18670	0.004502	0.03347	0.02496	EPAS1/KLF2/SPI1/LYN/ZFP36/JMJD6/STAT3/PTPN2/LYAR/THRA/BCL6/SMAD5/CEBPG/STAT1/JAK2/LDB1/HMOX1/TMOD3/HCLS1/AXL/FAM210B/ZBTB7A/HIF1A/PRDX1/SRF/VEGFA/CASP3/TMEM14C/ISG15/RPS24/MFHAS1/KLF13/ACVR1B/G6PD/TAL1/ETS1/IKZF1/RPS19/KMT2E/BMP4/HMGB2/ID2/SFXN1/INHBA/IREB2/DMTN/ARNT/DYRK3/NFE2L1/ERCC2/SLC4A1/EPB42/RB1/INHA/AMPD3/SLC25A38/ADAR/TRIM58/PRMT1/DNASE2/FOXO3	61
BP	GO:1903409	reactive oxygen species biosynthetic process	61/7096	122/18670	0.004502	0.03347	0.02496	KLF4/NQO1/KLF2/FYN/CX3CR1/ATP2B4/ACP5/GCH1/CLEC7A/SOD1/ARG2/STAT3/PTGS2/JAK2/TNF/DDAH2/PKD2/TICAM1/CYP1B1/CD36/PTK2B/INSR/HBB/PTX3/MPV17L/TLR4/IL1B/AIF1/CLU/RAC1/GLA/SPR/CYP1A2/DNM2/HDAC4/CD47/CYBA/CYBB/UCP1/AGXT2/SLC25A33/MAOB/RORA/IFNG/SLC7A2/CD34/HSP90AB1/DUOXA1/WDR35/MTOR/RHOA/SNCA/ABCD1/SLC30A10/ROCK2/CTNS/MPO/RAB27A/TLR6/FOXO3/GCHFR	61
BP	GO:0050704	regulation of interleukin-1 secretion	30/7096	53/18670	0.004525	0.03361	0.02505	NOD2/IL1R2/WNT5A/ARG2/LILRA5/NLRP3/TNFAIP3/LILRA2/NLRP12/P2RX7/AIM2/TRIM16/PANX1/SERPINB1/TLR4/PML/HMGB1/CASP1/LGALS9/FZD5/CPTP/TLR8/APOA1/NLRP1/NLRP2/FOXP1/CCL19/CCR7/HMGB4/IGHD	30
BP	GO:0006809	nitric oxide biosynthetic process	41/7096	77/18670	0.004585	0.03402	0.02536	KLF4/NQO1/KLF2/CX3CR1/ATP2B4/ACP5/GCH1/CLEC7A/ARG2/PTGS2/JAK2/TNF/DDAH2/PKD2/TICAM1/CYP1B1/CD36/PTK2B/INSR/HBB/PTX3/TLR4/IL1B/AIF1/CLU/RAC1/GLA/SPR/DNM2/CD47/AGXT2/RORA/IFNG/SLC7A2/CD34/HSP90AB1/WDR35/MTOR/ROCK2/TLR6/GCHFR	41
BP	GO:0044272	sulfur compound biosynthetic process	91/7096	192/18670	0.004768	0.03533	0.02634	PDK4/VCAN/GCLM/CHSY1/CBR4/NDST2/ADI1/MTR/PAPSS1/ACSL5/MGST2/GSTP1/SLC7A11/ELOVL5/CHST13/PDK2/GGCT/B3GNT2/ESD/APIP/SCD/AKR1A1/CHST2/B4GALT6/CSGALNACT1/ACSL4/ACLY/MTRR/GCLC/ENOPH1/GSTO1/GSTZ1/CSPG4/TECR/ST3GAL2/XYLT1/CHST11/MPC2/ACACB/TPK1/SLC35D1/GSTA1/HAGH/B3GALT6/ELOVL7/GLCE/CHST5/GSTM3/CHST14/MLYCD/XYLT2/MTAP/ACSL6/MGST1/MPST/GSTM5/PAPSS2/CTH/BHMT/NDST1/GSS/PDK1/CSGALNACT2/CNDP2/HPGDS/PDHB/B4GALT5/BCAN/GSTM4/DLAT/NFE2L2/PDP2/GGT7/PDHA2/MGST3/B3GNT4/GGTA1P/GGT5/ST3GAL1/PDP1/CHST12/CHAC2/SNCA/B4GALT1/ELOVL6/GGTLC1/PDPR/SLC35D2/MAT1A/HSD17B12/CHST7	91
BP	GO:0009152	purine ribonucleotide biosynthetic process	128/7096	280/18670	0.004773	0.03533	0.02634	IGF1/CBFA2T3/HK3/PDK4/LDHA/PINK1/FBP1/PGK1/CBR4/VPS9D1/STAT3/PFKFB3/NUP62/NUP160/PFKM/PFKP/GAPDH/PANK2/NUP214/ACOT7/PAPSS1/ACSL5/SLC2A6/P2RX7/ELOVL5/NUPR1/AK3/PGAM1/AK2/PKM/PDK2/GALK1/EIF6/TPI1/ZBTB7A/TGFB1/GMPS/NUP85/HIF1A/SCD/SEH1L/PANK3/ADK/INSR/ALDOC/PANK1/GUK1/PAICS/NUP43/IMPDH1/ACSL4/ACLY/ENO1/DNAJC30/ALDOA/GSTZ1/TECR/POM121/MPC2/ACACB/OGDH/ELOVL7/GPI/ADCY7/PFKFB4/PPARGC1A/FLCN/MLYCD/ADCY1/DHTKD1/NME3/ACSL6/SLC25A12/LDHC/NME4/PRKAG2/MYOG/NCOR1/PFKFB1/ATIC/ADCY3/NUP88/HDAC4/PAPSS2/NME1/NUP107/PDK1/PPAT/PDHB/FOXK2/DDIT4/AMPD2/PGK2/PFKFB2/ARNT/DLAT/PDP2/PPARA/NUP93/SLC25A13/PRKAA1/PSEN1/PDHA2/NUP205/ENO2/PID1/GUCY2D/SLC4A1/TREM2/NUP50/IFNG/PRKAG1/OGT/PDP1/ESRRB/ZBTB20/VCP/ADPGK/TAZ/APP/SNCA/ELOVL6/AMPD3/PDPR/PFKL/POM121C/AAAS/HSD17B12	128
BP	GO:0010950	positive regulation of endopeptidase activity	85/7096	178/18670	0.004851	0.03582	0.02671	S100A9/S100A8/FYN/CLEC7A/BCL10/LYN/AIFM1/GRAMD4/STAT3/CTSD/NLRP3/TNFRSF10A/PMAIP1/MBP/LGMN/MYC/NLRP12/JAK2/FAS/BCAP31/TNF/IFT57/PRELID1/PSME1/AIM2/FIS1/ARRB1/TFAP4/HTRA2/CYFIP2/TNFSF10/CASP8/AGER/ADRM1/DAPK1/PML/CASP5/HMGB1/TRADD/PPM1F/SIRT1/TTBK1/LCK/CR1/EGLN3/PDCD5/DDX3X/PRR7/BCL2L11/P2RX1/PSME3/MEFV/BAX/CRADD/CASP1/KHDC1/LGALS9/ST20/MAP3K5/F2R/TNFRSF10B/MUL1/FADD/TRAF2/CASP4/COL4A3/BAD/DAP/NLRP1/ST18/NLRP2/WDR35/DIABLO/F3/VCP/RHOA/SNCA/MALT1/BAK1/PICALM/ROCK2/AKIRIN2/MIR205/EFNA3/SOX7	85
BP	GO:0022406	membrane docking	85/7096	178/18670	0.004851	0.03582	0.02671	EZR/PRKAR2B/TUBA1A/STX7/NINL/STX11/TCTN1/RAB11A/CHP1/ESYT2/ATG14/CTBP2/ODF2/EXOC6B/HAUS8/PEX16/CNTRL/STXBP1/UNC13B/CEP164/PCM1/STXBP2/CSNK1D/CEP131/VAMP3/SFI1/PAFAH1B1/CDK5RAP2/VPS33A/BLOC1S6/CEP76/MAPRE1/VAPB/RAB8A/PDZD8/STX5/PSEN2/B9D1/CSNK1E/TCTN2/HAUS2/NPHP4/VPS18/KIF24/PRKACA/CKAP5/DCTN2/CEP152/TUBA4A/STX16/PLEK/MKS1/CAMK2A/YKT6/CEP63/RAB8B/CEP57/CETN2/HAUS5/TUBB4A/HAUS1/RAB3A/STX12/PPFIA3/YWHAE/CEP83/MSN/VTI1B/SYTL2/EXOC4/FGFR1OP/STX8/SYT1/RAB3B/SCFD1/YWHAG/STXBP3/SNAP29/TCTN3/RABEPK/RAB3D/TTBK2/CEP78/C2CD3/ALMS1	85
BP	GO:0010975	regulation of neuron projection development	218/7096	499/18670	0.004867	0.0359	0.02676	KLF4/S100A9/RTN4R/FN1/FYN/DPYSL3/SIPA1L1/DPYSL2/SKIL/GRN/ARF6/LYN/DNM3/WNT5A/DENND5A/TSC1/SEMA4B/VIM/LRIG2/SPP1/RAB11A/CAMK1D/MAP2K1/CIB1/ULK2/RGS2/YWHAH/CERS2/ALK/DVL2/EZH2/EPHB2/MOV10/ARHGDIA/IFRD1/APOE/GSK3B/ZEB2/ZSWIM6/ACTR2/PLAA/CXCL12/PTPRO/PLXNB2/LRP8/UBE3A/TWF2/SIN3A/DGUOK/ARSB/HGF/PAK1/RAPGEF2/MEGF8/SS18L2/PTK2B/PLXNC1/BCL11A/SRF/SCN1B/BAIAP2/SEMA4A/ITSN1/HSPA5/NCK1/FIG4/VEGFA/CDK5/PLK2/TNFRSF12A/TRAK2/ABL1/PAFAH1B1/CTSZ/SRGAP2C/GDI1/GRIP1/CREB3L2/FBXO38/PTK6/SEMA4C/RAP1A/PAQR3/SEMA4D/MARK1/ANKRD27/LRP1/CRK/NPTN/BMP7/TMEM106B/RAB29/CAPRIN1/CCDC88A/KALRN/LRRK2/DCC/CYFIP1/MYCBP2/ARC/CRTC1/PTK2/ARF1/SETX/SEMA6B/PDLIM5/PLXNA1/HDAC2/BMP5/NRP1/DISC1/SEMA3B/PLXND1/DNM2/NEDD4/AVIL/L1CAM/MARK2/NME1/CFL1/LPAR3/KANK1/IST1/LGALS1/NDEL1/SYNGAP1/DAB1/OLFM1/MOB2/INPP5F/RTN4RL1/WDR36/SHANK1/CPEB3/SEMA5A/ITGA3/LPAR1/FSTL4/SLC39A12/BHLHB9/DNM1L/AP2A1/FZD1/NFE2L2/NSMF/CNTF/MUL1/AMIGO1/ABL2/SS18L1/FZD4/PREX1/ITSN2/SLIT2/LRRC7/DVL1/PSEN1/FMR1/GPC2/MDM2/SEMA5B/CHRNB2/SHOX2/RTN4RL2/KATNB1/RASAL1/MAP3K13/RUFY3/PLXNA3/SPOCK1/CDC20/SYT1/RET/TRAK1/CPNE9/TMEM30A/NR2F1/ULK4/IL1RAPL1/PPP2R5B/ACAP3/KNDC1/PLXNA2/SYT2/CARM1/NR2E1/SYT4/RELN/MAP4K4/MTOR/CHODL/RHOA/TRPV4/BRSK1/RTN4/C21orf91/CX3CL1/BAG5/PARP6/CRABP2/KREMEN1/RIMS2/ASAP1/FGF13/LRP4/WNT7A/LZTS1/SHANK3/KEL/MACF1/CNTN1/TRPV2/ZMYND8/NTRK2/MEF2C/TRIM46/CAMK2B/BMPR2	218
BP	GO:0016241	regulation of macroautophagy	82/7096	171/18670	0.004875	0.03592	0.02678	ATP6V0D2/PINK1/TSC1/C9orf72/GNAI3/GAPDH/RNF41/ATP6V1C1/FEZ2/UCHL1/SEC22B/HMOX1/ATP6V0C/NUPR1/TRIM13/CHMP4B/CDC37/EXOC1/HIF1A/ATG101/IKBKG/HTRA2/QSOX1/SPTLC2/CDK5/CASP3/ATP6V1A/RAB3GAP1/LAMTOR1/RRAGD/ATG13/NPRL3/SIRT1/GPSM1/ATP6V1B2/MLST8/LRRK2/ATP6V1D/SNX6/PHF23/PRKAG2/VPS13D/LAMTOR4/MAPK8/EPM2A/UBQLN2/NEDD4/ATP6V0E2/PRKACA/RAB5A/ADRB2/USP30/ATP6V1G2/RRAGA/LAMTOR5/ULK1/SESN1/PRKAA1/MTMR3/SNX5/SH3GLB1/IFT20/SMCR8/NPRL2/EXOC4/PRKAG1/SCFD1/CLEC16A/RNF5/LACRT/OPTN/VPS26B/MTOR/PIM2/ERN1/ATP6V1B1/LZTS1/SESN2/SLC38A9/CAPNS1/SNX32/PRKAB1	82
BP	GO:0006353	DNA-templated transcription, termination	40/7096	75/18670	0.004888	0.03597	0.02682	PCF11/MTERF1/LSM11/CSTF3/XRN2/CCNH/MTERF2/SNRPB/DHX9/POLR2L/SYMPK/TAF1B/CPSF3/CLP1/POLR2H/PAPOLA/SCAF8/SETX/GTF2H4/FIP1L1/SNRPF/TAF1D/POLR1C/CSTF1/POLR2F/PRMT5/ZMPSTE24/POLR2K/ERCC2/SCAF4/TAF1C/MAZ/CPSF2/TBP/CD3EAP/CPSF1/CPSF7/POLR3K/SNRPG/ZNF473	40
BP	GO:0006473	protein acetylation	96/7096	204/18670	0.004948	0.03633	0.02708	SPI1/POR/BAZ1A/DR1/LDB1/MORF4L2/HAT1/NUPR1/GSK3B/SUPT7L/KAT2B/MRGBP/TRIM16/TGFB1/SIN3A/ZNF451/NATD1/JADE3/ARRB1/NAA20/NCOA3/PCGF2/RUVBL2/RUVBL1/EPC2/MBIP/MSL3/NAA10/MBD3/KAT7/YEATS4/SETD5/TAF5L/IL1B/DSCC1/KAT8/TAF12/CRTC2/SIRT1/NAA40/BRD8/TAF5/PPARGC1A/FLCN/MCRS1/MIR34A/MUC1/SPHK1/HDAC2/KAT5/ELP3/BRPF1/NOC2L/DPF2/CTCF/RSF1/EHHADH/PHF20/ZMPSTE24/BLOC1S1/TAF6L/NAA16/BRCA1/ING3/FAM161A/HINT2/KANSL1L/CLOCK/EPC1/KAT2A/PRKAA1/PHF10/CPA4/TAF9B/EID1/ARNTL/OGT/MCM3AP/LACRT/ING4/SET/JADE1/NAA15/USP22/SNCA/MSL1/SOX4/POLE4/TADA3/PAXIP1/ACTL6A/KLF15/KAT6B/WDR5/TAF7/NAA60	96
BP	GO:1902905	positive regulation of supramolecular fiber organization	96/7096	204/18670	0.004948	0.03633	0.02708	S100A10/CDC42EP4/VASP/ARF6/FHOD1/TSC1/SORBS3/HCK/RHOBTB1/FLNA/RHOC/RGCC/SPIRE1/IQGAP2/APOE/ARHGEF10L/ACTR2/EVL/PSRC1/PFN1/CDC42EP2/PAK1/CLIP1/PTK2B/CFL2/SWAP70/GMFG/CORO1A/BAIAP2/NCK1/ABL1/FCHSD1/CDK5RAP2/ARPC1A/MAPRE1/CLU/PPM1F/RAC1/ARPIN/ARPC1B/CDC42EP3/CYFIP1/MYO1C/CORO1B/LIMCH1/ARF1/ARPC5L/NRP1/TPM1/CD47/CDKN1B/CFL1/GRB2/PLEK/JMY/ACTR3B/FER/SEMA5A/LPAR1/ACTR3/PXN/LMOD3/CAV3/SCIN/CCL26/PSEN1/APOA1/KATNB1/ARPC4/TGFB3/SLAIN2/RB1/SYNPO2L/ARPC2/GPX1/MTOR/NAV3/RHOA/TRPV4/PICK1/APP/CX3CL1/ITGB1BP1/SNX9/MET/CCR7/WAS/ROCK2/RHOBTB2/CCL24/SERPINF2/BIN1/NCKAP1/FCHSD2/SYNPO/FMN1	96
BP	GO:0010256	endomembrane system organization	193/7096	438/18670	0.005026	0.0367	0.02736	MYOF/STAM/MPP5/SUN2/PPP2CA/ATP8B2/TANGO2/LMNA/SOD1/SYT11/BLOC1S2/PLSCR1/FCHO1/LMAN2L/RAB11A/FAM160A2/RFX2/PACSIN2/FCHO2/SNX10/MAP2K1/FLOT1/ALS2/SQSTM1/AGFG1/PTPRC/PSAP/P2RX7/AQP11/TMEM43/PLEKHM2/VPS37B/GOLGA8A/CHMP4B/GOLGB1/SGTA/ARL6IP1/SYNJ1/CSNK1D/PRKCD/ATL1/MICALL1/TMCC1/BAIAP2/ARFGEF1/KIFC3/UBXN2B/GORASP2/CLCN3/DNAJC28/SYNGR2/PAFAH1B1/RAB3GAP1/ABCA1/EMD/TMED10/TMEM33/DTNBP1/LAMTOR1/NSFL1C/VPS37C/VTA1/PDE4DIP/ATP8B1/CREB1/VAPB/CLU/HOOK2/RAB43/NDRG1/RAB33B/RAB29/SPTBN1/TOR1B/SNX33/LRRK2/ARV1/RAB38/ANKLE2/STX5/BIN2/SERP1/MYH9/CSNK1A1/RTN3/TMEM127/BANF1/TOR1A/PLA2G3/DNM1/PLK3/NPLOC4/XKR8/ANXA6/HOOK3/ATL3/VPS18/GOLPH3L/DNM2/VPS51/TBC1D20/BLOC1S3/GOLGA5/CHMP2A/BCAS3/TXNDC8/COG4/TSG101/PI4K2A/IST1/NDEL1/SYTL4/HGS/GET4/STX16/SH3TC2/MAP2K2/OSBPL2/TJAP1/LMAN1/ARL1/VTI1A/ZW10/CHMP1A/UGCG/VPS4B/PRMT5/ZMPSTE24/CORO1C/F2R/BLOC1S1/STX18/HACE1/ABCA7/TMED5/VPS25/ACRBP/ANO4/LAPTM4B/CLASP2/SEC23IP/NUP93/TBPL1/CAV3/BIN3/ATP2A2/DMKN/RAB22A/SRGN/TMED4/RAB3A/MAPK1/VRK1/SH3GLB1/SYPL2/COG2/CASQ1/SPAG4/SLC4A1/COG1/SPTA1/PARP11/SNX19/EHD3/TMEM38B/LEMD3/COG7/TMEFF2/OPTN/REEP3/ALS2CL/SYT4/TRAPPC8/PLSCR4/RTN4/SNX9/BAG5/PDCD10/ABCD1/MTSS1/ASAP1/CHMP1B/DYM/UBL4A/TARDBP/PRKCA/RAB27A/BIN1/TRAPPC11/PACSIN3/SEC31B/SEC16B/PLSCR2	193
BP	GO:0071214	cellular response to abiotic stimulus	149/7096	331/18670	0.005057	0.0367	0.02736	CRIP1/MYD88/PKD2L1/BMF/PTGER4/NAMPT/CDKN1A/BCL10/OXSR1/IRF1/MCOLN1/ATP1A1/AKR1B1/NMT2/RAD51AP1/PTGS2/TNFRSF10A/CHP1/GNB1/CD40/MYC/FAS/EGR1/SLC9A1/NFKB1/PKD2/ERCC4/ATF4/RAD1/TGFB1/PTAFR/TLR5/MAPK13/METTL3/USP28/RUVBL2/ZBTB1/HYAL2/MBIP/TMEM161A/DDB1/INTS7/TLR4/HABP4/TMEM109/NET1/HSPA5/CASP3/HRAS/RELB/NPM1/GCLC/CASP8/IL1B/XRCC5/ARHGEF2/CASP5/METAP2/PDE6G/SIRT1/LRRC8D/RAC1/EIF2S1/RHNO1/DDX3X/EFHD1/ATM/TNKS1BP1/POLH/CNN2/ACTR5/HVCN1/MYOG/MAPK8/DNM2/PCNA/NEDD4/BAX/NOC2L/ERCC1/CRADD/HDAC4/CASP2/YY1/CDC25A/CASP1/ITGA2/OPN3/SWI5/TSPYL5/GRB2/CYBA/ST20/MICU1/HYAL3/YBX3/LIG4/ZMPSTE24/KDM4D/SDE2/TNFRSF10B/FBXO4/IMPACT/C9orf116/NSMF/E2F4/MYLK/EGFR/FADD/ATR/CLOCK/LETM1/TLR8/FMR1/HAMP/MDM2/DDB2/GUCY2D/MAP2K4/POLD1/BAD/XRCC6/RBL2/CAPN3/RAD9A/CUL4B/GRK4/MAP3K1/TLR3/GPR52/SERPINB6/EIF2AK4/TRPV4/TRIAP1/DAG1/ENG/BAK1/MGMT/ATP1A2/LRRC8E/RGR/GJA1/NUCKS1/SPIDR/GNA11/RP1/OPN4/FIGNL1/SLC12A6	149
BP	GO:0104004	cellular response to environmental stimulus	149/7096	331/18670	0.005057	0.0367	0.02736	CRIP1/MYD88/PKD2L1/BMF/PTGER4/NAMPT/CDKN1A/BCL10/OXSR1/IRF1/MCOLN1/ATP1A1/AKR1B1/NMT2/RAD51AP1/PTGS2/TNFRSF10A/CHP1/GNB1/CD40/MYC/FAS/EGR1/SLC9A1/NFKB1/PKD2/ERCC4/ATF4/RAD1/TGFB1/PTAFR/TLR5/MAPK13/METTL3/USP28/RUVBL2/ZBTB1/HYAL2/MBIP/TMEM161A/DDB1/INTS7/TLR4/HABP4/TMEM109/NET1/HSPA5/CASP3/HRAS/RELB/NPM1/GCLC/CASP8/IL1B/XRCC5/ARHGEF2/CASP5/METAP2/PDE6G/SIRT1/LRRC8D/RAC1/EIF2S1/RHNO1/DDX3X/EFHD1/ATM/TNKS1BP1/POLH/CNN2/ACTR5/HVCN1/MYOG/MAPK8/DNM2/PCNA/NEDD4/BAX/NOC2L/ERCC1/CRADD/HDAC4/CASP2/YY1/CDC25A/CASP1/ITGA2/OPN3/SWI5/TSPYL5/GRB2/CYBA/ST20/MICU1/HYAL3/YBX3/LIG4/ZMPSTE24/KDM4D/SDE2/TNFRSF10B/FBXO4/IMPACT/C9orf116/NSMF/E2F4/MYLK/EGFR/FADD/ATR/CLOCK/LETM1/TLR8/FMR1/HAMP/MDM2/DDB2/GUCY2D/MAP2K4/POLD1/BAD/XRCC6/RBL2/CAPN3/RAD9A/CUL4B/GRK4/MAP3K1/TLR3/GPR52/SERPINB6/EIF2AK4/TRPV4/TRIAP1/DAG1/ENG/BAK1/MGMT/ATP1A2/LRRC8E/RGR/GJA1/NUCKS1/SPIDR/GNA11/RP1/OPN4/FIGNL1/SLC12A6	149
BP	GO:0033004	negative regulation of mast cell activation	10/7096	13/18670	0.005066	0.0367	0.02736	HMOX1/CD300LF/CD300A/LGALS9/FER/RABGEF1/CNR2/IL13RA2/CD84/FOXF1	10
BP	GO:0034982	mitochondrial protein processing	10/7096	13/18670	0.005066	0.0367	0.02736	IMMP1L/UQCRC2/SIRT4/MIPEP/YME1L1/OMA1/AFG3L2/LRRK2/IMMP2L/PMPCB	10
BP	GO:0045820	negative regulation of glycolytic process	10/7096	13/18670	0.005066	0.0367	0.02736	CBFA2T3/FBP1/STAT3/NUPR1/PPARGC1A/MYOG/PFKFB1/HDAC4/DDIT4/PPARA	10
BP	GO:0060340	positive regulation of type I interferon-mediated signaling pathway	10/7096	13/18670	0.005066	0.0367	0.02736	IRF7/WNT5A/NLRC5/UBE2K/MMP12/MAVS/LSM14A/ZBP1/FADD/TRIM6	10
BP	GO:0071027	nuclear RNA surveillance	10/7096	13/18670	0.005066	0.0367	0.02736	XRN1/EXOSC2/EXOSC7/DXO/EXOSC9/EXOSC3/PCID2/EXOSC6/EXOSC8/EXOSC5	10
BP	GO:0071028	nuclear mRNA surveillance	10/7096	13/18670	0.005066	0.0367	0.02736	XRN1/EXOSC2/EXOSC7/DXO/EXOSC9/EXOSC3/PCID2/EXOSC6/EXOSC8/EXOSC5	10
BP	GO:0071285	cellular response to lithium ion	10/7096	13/18670	0.005066	0.0367	0.02736	FABP4/CEBPA/ADCY7/XRCC4/MYOG/ID2/CDKN1B/LIG4/CALR/TPH2	10
BP	GO:0090594	inflammatory response to wounding	10/7096	13/18670	0.005066	0.0367	0.02736	CCR2/GRN/SIGLEC10/HMOX1/TGFB1/HIF1A/AGER/TIMP1/IL1A/F2R	10
BP	GO:1902894	negative regulation of pri-miRNA transcription by RNA polymerase II	10/7096	13/18670	0.005066	0.0367	0.02736	PPARD/RELA/NFATC3/SRF/LILRB4/PDGFB/BMP4/HDAC4/YY1/PPARA	10
BP	GO:0032092	positive regulation of protein binding	48/7096	93/18670	0.005108	0.03696	0.02755	ARF6/PPP2CA/WNT5A/LFNG/FLOT1/HFE/RAN/APOE/GSK3B/TICAM1/ARRB1/RAPGEF2/SYAP1/BMP2/CDK5/PLK2/ABL1/MAPRE1/LRP1/LRRK2/DTX3L/MARK3/NRP1/MMP9/PLXND1/PLCL1/BMP4/DERL1/TRAF2/ANXA2P2/PSEN1/TCF7L2/CTHRC1/EPB41/PLCL2/SPTA1/GNL3L/PIN1/HSP90AB1/MEN1/TERT/ANXA2/APP/TIRAP/HOXA3/TRAF4/GCG/MEF2C	48
BP	GO:0001738	morphogenesis of a polarized epithelium	69/7096	141/18670	0.005131	0.03708	0.02765	WNT5A/CELSR2/PSMB9/PSMB8/PSMA5/DVL2/PSMD11/PSME1/DAAM1/PFN1/PSMB10/PSMA1/PSMA4/ROR2/FUZ/ABL1/PAFAH1B1/OPHN1/PSMB1/SAPCD2/PSMC4/INTU/PSMD13/PSMB3/SH3BP1/RAC1/PSMB5/PSMD6/PSMC3/AP2A2/PSME3/PSMC6/ROR1/AP2S1/MKS1/FZD5/AP2A1/FZD1/FZD4/DVL1/WNT1/ASTN2/CTHRC1/IFT20/MSN/PSMC1/PSMD8/PSMA2/ANKRD6/FZD7/PSMC5/FOXF2/TRAF3IP1/PSMC2/AP2M1/GPC4/PSMB2/PSMD4/RHOA/BRSK1/FZD2/GRHL3/FOXF1/PSMD1/WNT7A/PSMB4/PSMD9/PSMD3/LAMA1	69
BP	GO:0045453	bone resorption	34/7096	62/18670	0.005154	0.03721	0.02774	SIGLEC15/RAC2/PDK4/ACP5/CSK/ATP6AP1/TPP1/SPP1/TNFAIP3/S1PR1/SNX10/CTSK/P2RX7/ADAM8/PTK2B/TRAF6/TCIRG1/LTBP3/TNFRSF11A/IL7/RAC1/PLEKHM1/IL6/TMEM64/ADRB2/EGFR/TFRC/DCSTAMP/CLDN18/CSF1R/RAB3D/IAPP/TMEM119/PRKCA	34
BP	GO:0140056	organelle localization by membrane tethering	81/7096	169/18670	0.005203	0.03752	0.02797	PRKAR2B/TUBA1A/STX7/NINL/STX11/TCTN1/RAB11A/ESYT2/ATG14/CTBP2/ODF2/EXOC6B/HAUS8/CNTRL/STXBP1/UNC13B/CEP164/PCM1/STXBP2/CSNK1D/CEP131/VAMP3/SFI1/PAFAH1B1/CDK5RAP2/VPS33A/BLOC1S6/CEP76/MAPRE1/VAPB/RAB8A/PDZD8/STX5/PSEN2/B9D1/CSNK1E/TCTN2/HAUS2/NPHP4/VPS18/KIF24/PRKACA/CKAP5/DCTN2/CEP152/TUBA4A/STX16/PLEK/MKS1/CAMK2A/YKT6/CEP63/RAB8B/CEP57/CETN2/HAUS5/TUBB4A/HAUS1/RAB3A/STX12/PPFIA3/YWHAE/CEP83/VTI1B/SYTL2/EXOC4/FGFR1OP/STX8/SYT1/RAB3B/SCFD1/YWHAG/STXBP3/SNAP29/TCTN3/RABEPK/RAB3D/TTBK2/CEP78/C2CD3/ALMS1	81
BP	GO:0046128	purine ribonucleoside metabolic process	39/7096	73/18670	0.005211	0.03753	0.02798	PNP/GNAI3/ACPP/AHCY/RAN/AK3/NFS1/MPP1/HDDC3/GMPS/DGUOK/RAB23/APIP/ADK/MBIP/GUK1/IMPDH1/MTRR/ENOPH1/MOCS2/PRTFDC1/LRRK2/NME3/MTAP/NME4/GTPBP1/GMPR2/RHOQ/NME1/GAMT/MOCS3/ADA/AHCYL2/AHCYL1/RHOA/ENPP4/AMPD3/ADAL/GIMAP7	39
BP	GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	27/7096	47/18670	0.005267	0.03773	0.02813	NFKBIZ/ANXA1/BCL6/NLRP3/SH3RF1/SMAD7/IL4R/CBFB/SOCS5/ZBTB7B/NFKBID/HMGB1/IL12RB1/LGALS9/HLX/IL18/TNFSF4/SOCS1/IFNG/IL12B/PRKCZ/CD80/TBX21/CD83/CCL19/MALT1/IL23A	27
BP	GO:0045058	T cell selection	27/7096	47/18670	0.005267	0.03773	0.02813	STAT6/STAT3/PTPN2/LY9/PTPRC/IL15/BATF/CD74/SRF/CD3D/IL6/CYLD/BCL2/CD3G/CD1D/IL12RB1/THEMIS/BCL11B/CD4/IL12B/TBX21/MTOR/RHOA/FOXN1/CCR7/CD3E/IL23A	27
BP	GO:0046638	positive regulation of alpha-beta T cell differentiation	27/7096	47/18670	0.005267	0.03773	0.02813	PNP/NFKBIZ/ANXA1/NLRP3/IL4R/CBFB/SOCS5/ZBTB7B/NFKBID/IL12RB1/LGALS9/ADA/HLX/IL18/AP3B1/TNFSF4/SOCS1/IFNG/IL12B/PRKCZ/CD80/RHOA/CD83/CCL19/MALT1/ZBTB16/IL23A	27
BP	GO:0048066	developmental pigmentation	27/7096	47/18670	0.005267	0.03773	0.02813	HPS4/KITLG/ZEB2/MYO5A/CD63/VPS33A/MITF/BLOC1S6/ANKRD27/ATP6AP2/RAB32/RAB38/BCL2L11/BCL2/BLOC1S3/BAX/GPR143/DCT/AP1G1/HPS6/AP1M1/MREG/OCA2/RAB27A/GNA11/ADAMTS9/MEF2C	27
BP	GO:0070231	T cell apoptotic process	27/7096	47/18670	0.005267	0.03773	0.02813	TSC22D3/PIP/BCL10/WNT5A/ARG2/SLC46A2/ADAM8/PRELID1/IL7R/DOCK8/HIF1A/CLC/IDO1/NFKBID/DFFA/CCL5/BCL2L11/BMP4/BAX/CD274/LGALS9/ADA/FADD/PTCRA/PRKCQ/BAK1/PDCD1	27
BP	GO:0018205	peptidyl-lysine modification	176/7096	397/18670	0.00534	0.03821	0.02849	SPI1/POR/BAZ1A/LMNA/JMJD6/HMG20A/NUP62/DR1/ZBED1/NUP160/PHF19/SIRT4/NUP214/DPY30/SETDB2/LDB1/MORF4L2/EGR1/SENP6/ZNF304/EZH2/HAT1/WDR5B/VCPKMT/DOT1L/SUPT7L/KAT2B/LIPT1/MRGBP/SUV39H2/TET2/RELA/TRIM16/TGFB1/SIN3A/ZNF451/NUP85/JADE3/ARRB1/SETD4/NCOA3/SEH1L/BCL11A/PCGF2/RUVBL2/RUVBL1/EPC2/MBIP/NSD1/LOXL2/MSL3/NUP43/MBD3/KAT7/SETMAR/YEATS4/SETD5/TAF5L/IL1B/NSMCE2/KAT8/TAF12/POM121/RNF113A/CRTC2/SIRT1/TRPM4/NAA40/METTL21A/SETD7/EGR2/BRD8/TAF5/PLOD1/SMYD3/PPARGC1A/METTL22/FLCN/BCOR/SUMO1/MCRS1/MUC1/HDAC10/KMT2E/HDAC2/IFIH1/KAT5/SUV39H1/UBA2/ASH1L/SIRT5/ELP3/TGM2/SETD6/NUP88/BRPF1/NOC2L/HDAC4/CTH/DPF2/TOLLIP/CTCF/PLOD2/NUP107/SETDB1/VIPAS39/USPL1/RSF1/CBX4/PHF20/ZMPSTE24/KDM4D/ARNT/BLOC1S1/PIAS3/TAF6L/PWP1/BRCA1/ING3/MUL1/NUP93/HINT2/KANSL1L/CLOCK/EPC1/KAT2A/PRKAA1/NUP205/PHF10/MDM2/CPA4/TAF9B/CAPN3/PRDM2/RNF212B/EID1/NUP50/PRDM6/OGT/SUMO4/ATP7A/UBE2I/GNL3L/MCM3AP/RLF/ING4/SET/MEN1/JADE1/KMT2B/TOPORS/HMG20B/USP22/SNCA/MSL1/SOX4/PAX5/POLE4/GCG/EZH1/TADA3/PAXIP1/DHPS/ACTL6A/GNL3/WDR82/KLF15/KAT6B/KIAA1586/RASD2/WDR5/POM121C/AAAS/TAF7/ZNF335/NAA60	176
BP	GO:0046209	nitric oxide metabolic process	43/7096	82/18670	0.005401	0.03859	0.02877	KLF4/NQO1/KLF2/CX3CR1/TLR2/ATP2B4/ACP5/GCH1/CLEC7A/POR/ARG2/PTGS2/JAK2/TNF/DDAH2/PKD2/TICAM1/CYP1B1/CD36/PTK2B/INSR/HBB/PTX3/TLR4/IL1B/AIF1/CLU/RAC1/GLA/SPR/DNM2/CD47/AGXT2/RORA/IFNG/SLC7A2/CD34/HSP90AB1/WDR35/MTOR/ROCK2/TLR6/GCHFR	43
BP	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	65/7096	132/18670	0.005406	0.03859	0.02877	S100A9/S100A8/CLEC7A/BCL10/AIFM1/GRAMD4/CTSD/NLRP3/TNFRSF10A/PMAIP1/MYC/NLRP12/JAK2/FAS/BCAP31/TNF/IFT57/FIS1/ARRB1/TFAP4/HTRA2/TNFSF10/CASP8/DAPK1/PML/CASP5/HMGB1/TRADD/PPM1F/SIRT1/LCK/EGLN3/PDCD5/DDX3X/PRR7/BCL2L11/P2RX1/BAX/CRADD/CASP1/KHDC1/LGALS9/ST20/MAP3K5/F2R/TNFRSF10B/MUL1/FADD/TRAF2/CASP4/COL4A3/BAD/DAP/NLRP1/ST18/NLRP2/WDR35/DIABLO/F3/VCP/RHOA/SNCA/MALT1/BAK1/SOX7	65
BP	GO:0036503	ERAD pathway	51/7096	100/18670	0.005423	0.03868	0.02883	RNF103/FBXO6/RNF139/BCAP31/TRIM13/TMEM129/EDEM1/UBE4B/SGTA/WFS1/SEC61B/ERLIN1/RNF175/HSPA5/FOXRED2/UBE2J1/ERLIN2/UBE2G2/SDF2L1/EDEM2/RNFT1/TOR1A/UBXN8/NPLOC4/STT3B/UBQLN2/PSMC6/MAN1B1/DNAJC10/DERL1/GET4/DNAJB9/DERL2/STUB1/NFE2L2/ATXN3/YOD1/HSP90B1/POMT2/TMUB2/UBXN1/FBXO27/FBXO44/RNF185/RNF5/VCP/USP19/EDEM3/DNAJC18/ERLEC1/OS9	51
BP	GO:1901653	cellular response to peptide	171/7096	385/18670	0.005461	0.0389	0.029	CRHBP/KLF4/IGF1/SH2B2/ATP6V0D2/FPR2/NOD2/KLF2/FYN/NAMPT/PDK4/PRKAR2B/APPL2/SOCS3/NR4A2/LYN/KLF3/POR/TSC1/CSK/SRSF5/SRD5A1/ATP6AP1/RAP1B/AKR1B1/STAT6/STAT3/PTPN2/CCND3/VIM/KLF10/ATP6V1C1/ADIPOR1/STAT1/LGMN/JAK2/GSTP1/PRKACB/C2CD5/ATP6V0C/SLC9A1/CISH/NFKB1/GSK3B/GAB1/RAB31/PIK3R3/KAT2B/GKAP1/PKM/RELA/PDK2/SLC2A8/CDK4/TGFB1/FIS1/PAK1/ENHO/CD36/MYO5A/PCK2/LEP/SYAP1/PRKCD/INSR/BAIAP2/TCIRG1/ITGA4/TLR4/PTPN22/ZBTB7B/IGF1R/NCK1/CDK5/ATP6V1A/GCLC/STAT5A/IL1B/AGTRAP/AGER/ARHGEF2/KLF11/SIK2/SHC1/PHIP/LRP1/CREB1/CRK/RAB8A/ATP6V1G3/SIRT1/ARID1B/EIF4EBP2/ATP6V1B2/ADCY7/IRS2/CYFIP1/MYO1C/DENND4C/MBD5/ADCY1/ATP6V1D/PTK2/GRB10/SNX6/BCL2L11/ADCY3/GNAI2/ATP6V0E2/INPP5K/GPR21/RHOQ/CPEB1/PRKACA/KANK1/ADRB2/KLF5/NDEL1/PPAT/GRB2/CYBA/TIMELESS/FOXO4/FER/CAMK2A/ATP6V1G2/PXN/NFE2L2/SERPINA12/AHCYL1/RAB8B/SLC25A33/CASP4/KL/WNT1/PRKAA1/PSEN1/MDM2/PID1/SOCS1/TREM2/ZNF106/OGT/NR4A3/CCNA2/MEN1/YWHAG/SLA2/PRKCZ/PRKCQ/HDAC5/APP/ATP6V1B1/SLC30A10/SMARCC1/GCG/GHR/BCL2L2/ROCK2/APPL1/SOCS2/KLF15/NUCKS1/NR1H4/STXBP4/MGARP/TLR6/CPEB2/FOXO3/GHRL/MIR146A	171
BP	GO:0021987	cerebral cortex development	58/7096	116/18670	0.005509	0.03918	0.02921	TRA2B/SUN2/TSC1/SRD5A1/FLNA/MBOAT7/BCL2A1/BTBD3/GSK3B/CSNK2A2/LRP8/HIF1A/PHACTR1/FBXO45/CDK5/PAFAH1B1/SRGAP2C/P2RY12/LRP1/BBS2/CRK/MKKS/ASPM/ARX/BBS4/DIXDC1/SYNE2/SRGAP2/NRP1/DISC1/TRAPPC9/ATIC/BAX/NRP2/PEX13/NDEL1/DAB1/CDK5R2/PLCB1/EGFR/SLIT2/PSEN1/YWHAE/BAD/TMEM14B/GNG12/NR2E1/RELN/CEP120/RHOA/RTN4/PAX5/EFHC1/FGF13/SMO/LHX6/KIF14/NTRK2	58
BP	GO:0046488	phosphatidylinositol metabolic process	83/7096	174/18670	0.005521	0.03918	0.02921	FPR2/HTR2B/SLC27A1/CDS1/PLA2G12A/SOCS3/PLEKHA1/MBOAT7/MTMR12/PIGV/PIGP/IMPAD1/PLBD1/CISH/PIGK/INPP1/PIK3R3/PTPN13/SACM1L/PIGN/IP6K1/SOCS5/SYNJ1/PITPNM1/TTC7A/SOCS6/FIG4/FAM126A/PLCG2/PIK3R6/PIGF/SYNJ2/CDIPT/PIGB/DPM1/OCRL/SOCS7/PDGFB/GPAA1/SH3YL1/ATM/ARF1/PIGM/PLEKHA8/SBF1/MTMR4/MPPE1/INPP5K/IMPA2/MTMR6/PIK3CD/PI4K2A/RAB5A/PIGQ/MTMR2/INPP5F/PLEK/PDGFA/PIGO/PIGH/PLCB1/PLCD4/DPM3/MTMR3/PLEKHA3/SOCS1/PIGT/MTMR9/PIK3CG/SLA2/CSF1R/PIP5K1B/VAC14/SOCS2/PGAP3/INPPL1/ARF3/EFR3A/PGAP1/INPP5A/PIK3CB/IMPA1/PI4KB	83
BP	GO:0031503	protein-containing complex localization	128/7096	281/18670	0.005524	0.03918	0.02921	KLHL21/EZR/STX7/DNM3/TSC1/NXF1/SRSF5/NUP62/NUP160/RAB11A/SMAD7/CHTOP/NUP214/ENY2/AGFG1/IFT172/TNFAIP2/TNPO1/RAN/IFT57/ALYREF/RNPS1/EIF6/KIF3B/MAGOHB/EXOC1/SARNP/NUP85/KIFAP3/NXT1/GRIPAP1/SEH1L/PCM1/DYNLL2/CEP131/YTHDC1/IFT80/NUP43/USP46/HRAS/NPM1/HNRNPA2B1/PURA/OPHN1/RBM8A/GRIP1/NUMB/WDR19/FYTTD1/DDX19B/U2AF1/RAP1A/POM121/ZNF593/SRSF3/SYMPK/BBS12/RAB8A/XPOT/SFPQ/TYROBP/NPTN/IFT46/CPSF3/RPGR/IFT52/ARC/ATM/DNM1/MAK/FIP1L1/NACC2/HSPB11/DNM2/NUP88/THOC2/SRSF6/SRSF7/GRASP/NUP107/DYNC2LI1/ADAM22/CDC40/DYNLRB1/THOC5/DYNLRB2/POLR2D/LCA5/U2AF1L4/EIF5A/NUP93/ATR/RCC2/IQSEC2/LTV1/LRRC7/THOC6/RIOK2/SSB/SRRM1/NUP205/EXOC3L1/IFT20/KIF17/WDR60/SRSF4/EIF4E/NUP50/DHX38/MCM3AP/PCID2/IFT22/CPSF2/WDR35/TRAF3IP1/PRKCZ/GPC4/RELN/DAG1/CPSF1/GSG1L/IFT74/RRS1/TTC30B/IFT81/POM121C/AAAS/UPF1	128
BP	GO:0016574	histone ubiquitination	26/7096	45/18670	0.005524	0.03918	0.02921	UBE2N/PAF1/UHRF1/RYBP/TRIM37/PCGF2/ATXN7L3/DDB1/PCGF1/PCGF3/UBR5/UBE2E1/UBE2A/CDK9/BCOR/DTX3L/KDM2B/RING1/LEO1/RNF20/PHC1/DDB2/CUL4B/USP22/CDC73/UBE2B	26
BP	GO:0006260	DNA replication	125/7096	274/18670	0.005693	0.04033	0.03007	ATG7/PPP2CA/BAZ1A/BARD1/BCL6/CDAN1/MCM6/FBXW7/GINS1/MCM2/SLFN11/NFIA/S100A11/GMNN/ALYREF/REPIN1/NFIX/RAD1/SIN3A/GTPBP4/ZNF830/ORC5/RPA1/PDS5A/SSBP1/RBBP6/ETAA1/DBF4B/KAT7/RMI2/SETMAR/RBBP7/HRAS/PRIM2/PURA/POLD4/ZPR1/WRNIP1/DNAJC2/DSCC1/HMGA1/SAMHD1/DHX9/DONSON/POLD2/RBBP4/TIPIN/RAC1/CCDC88A/DTD1/CDK9/POLI/RHNO1/RFC3/RNASEH1/ATM/POLH/ENPP7/KAT5/POLG/CCNE1/RAD17/RBMS1/PCNA/ORC6/BOD1L1/ANKRD17/RFWD3/RMI1/SSRP1/GEN1/TIMELESS/RECQL/ORC4/RRM2/LIG4/TICRR/ZMPSTE24/DTL/SDE2/CACYBP/POLL/BRCA1/EGFR/GINS4/ATR/RRM2B/MCM5/FANCM/RTEL1/MAP2K4/EXO1/CTC1/POLD1/SMC3/CLSPN/RAD9A/TOPBP1/NASP/CHAF1A/CCNA2/ING4/SET/POLA1/POLA2/ORC3/SUPT16H/LIG3/POLB/MCM8/NT5M/TOP1/POLE4/MCMBP/DUT/ATAD5/USP37/TONSL/PNKP/NUCKS1/FEN1/RECQL4/ZRANB3/E2F8/UPF1	125
BP	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress	25/7096	43/18670	0.005784	0.04089	0.03048	PINK1/SOD1/ZNF622/FBXW7/JAK2/CYP1B1/HIF1A/HSPB1/MAPK7/PRKCD/MCL1/HTRA2/PML/SIRT1/SFPQ/VNN1/BCL2/PDK1/GSKIP/MAP3K5/NFE2L2/DIABLO/GPX1/BAG5/PDCD10	25
BP	GO:0021762	substantia nigra development	25/7096	43/18670	0.005784	0.04089	0.03048	MBP/YWHAH/NDRG2/ACTB/RAD1/ZNF148/NDUFS3/HSPA5/CASP5/BASP1/GLUD1/TTBK1/SUDS3/G6PD/YWHAQ/GNB4/MAOB/SYNGR3/YWHAE/SYPL2/INA/MAPKAP1/CNP/RHOA/PLP1	25
BP	GO:0048771	tissue remodeling	85/7096	179/18670	0.005839	0.04123	0.03074	EPAS1/VDR/SIGLEC15/CCR2/RAC2/PDK4/ACP5/ANXA1/ACVR2B/NOTCH2/RBPJ/CSK/GPNMB/ATP6AP1/TPP1/SPP1/TNFAIP3/S1PR1/LIPA/SNX10/LGR4/CTSK/IL15/P2RX7/ADAM8/CST3/LRP5/AXL/TGFB1/HIF1A/PTK2B/LEP/TRAF6/TCIRG1/ABR/LTBP3/CSPG4/AGER/MITF/HMGB1/TNFRSF11A/IL7/RAC1/PLEKHM1/IL6/BCR/MIR34A/TMEM64/TGM2/BAX/TIMP1/IL1A/ADRB2/MMP14/F2R/SUCO/EGFR/IL18/TFRC/MDM2/DCSTAMP/MERTK/CTHRC1/TGFB3/ATP7A/HRG/CLDN18/DBH/IL12B/MMP2/CSF1R/RAB3D/IAPP/EFNA2/BAK1/HOXA3/ROCK2/TMEM119/GJA1/GREM1/PRKCA/IL23A/MEF2C/BMPR2/GDF5	85
BP	GO:0016197	endosomal transport	104/7096	224/18670	0.005881	0.04131	0.0308	STAM/RAB9A/ARF6/SNX1/DENND5A/BLOC1S2/ARL4C/RAB11A/HEATR5A/DENND1A/ALS2/ANKRD50/SQSTM1/DPY30/VPS37B/TBC1D5/DENND1B/CHMP4B/TMEM87A/AP5B1/GRIPAP1/MICALL1/TMCC1/CMTM6/SNX18/VAMP3/EHD4/ABCA1/GRIP1/LAMTOR1/RAB11FIP4/VPS37C/VTA1/ANKRD27/EHD1/RAB8A/RAB29/PREPL/GOSR2/AP5S1/SNX33/LRRK2/GOSR1/SNX27/CLTCL1/STX5/SNX6/TBC1D17/TOM1/VPS51/CHMP2A/MICALL2/CCDC93/RNF126/TSG101/GRASP/UBAP1/TMEM87B/HGS/STX16/UBC/INPP5F/VPS52/ARL1/VTI1A/CHMP1A/CLN5/ARFRP1/VPS4B/RAB7B/CORO1C/YKT6/BLOC1S1/VPS25/LAPTM4B/AP3B1/LRRC7/VPS29/SNX5/RAB35/AP5M1/VTI1B/LMTK2/RHOBTB3/EVI5/TBC1D10C/TMEM50A/EHD3/CLEC16A/SNX4/VPS16/VPS26B/VCP/DENND2A/ACAP2/SNX9/RGP1/WAS/CHMP1B/PICALM/ALMS1/TBC1D10B/SNX32/SNX17	104
BP	GO:0002688	regulation of leukocyte chemotaxis	57/7096	114/18670	0.005894	0.04131	0.0308	FPR2/CCR2/RAC2/DUSP1/BST1/LYN/OXSR1/WNT5A/VEGFB/CAMK1D/MIF/LGMN/PLA2G7/CD74/CXCL10/CXCL12/MPP1/PTK2B/SWAP70/CXCL13/VEGFA/CMKLR1/AIF1/CCL5/HMGB1/CCL7/RAC1/IL6/C3AR1/MOSPD2/GPSM3/ZNF580/TMEM102/SERPINE1/CCR6/GPR18/CREB3/LGALS9/CALR/MST1/C1QBP/CXCR2/ADAM17/JAM3/SLIT2/LBP/TRPV4/C5AR2/DAPK2/CCL19/TIRAP/CCL4/CCR7/GREM1/SLAMF8/IL23A/S100A14	57
BP	GO:0036465	synaptic vesicle recycling	37/7096	69/18670	0.005919	0.04131	0.0308	ARF6/DNM3/SYT11/POTEKP/FCHO2/DENND1A/PLAA/ACTB/PPP3CB/GRIPAP1/SYNJ1/ITSN1/CDK5/OPHN1/LRRK2/CYFIP1/DNAJC6/TOR1A/SH3GL1/DNM1/DNM2/RAB5A/KIAA1107/CANX/DNM1L/AP3B1/PLD2/RAB3A/SYT1/SYT2/SYT5/SNCA/WNT7A/PICALM/NLGN2/KIAA1109/AMPH	37
BP	GO:0006098	pentose-phosphate shunt	11/7096	15/18670	0.00594	0.04131	0.0308	TALDO1/PGAM1/RPE/TKT/RPIA/G6PD/PGM2/DERA/PGD/PGLS/RBKS	11
BP	GO:0009263	deoxyribonucleotide biosynthetic process	11/7096	15/18670	0.00594	0.04131	0.0308	ADK/CDADC1/GUK1/CMPK2/TYMS/RRM2/SHMT1/TBPL1/RRM2B/DCTD/DUT	11
BP	GO:0030812	negative regulation of nucleotide catabolic process	11/7096	15/18670	0.00594	0.04131	0.0308	CBFA2T3/FBP1/STAT3/NUPR1/PPARGC1A/SLC25A12/MYOG/PFKFB1/HDAC4/DDIT4/PPARA	11
BP	GO:0032352	positive regulation of hormone metabolic process	11/7096	15/18670	0.00594	0.04131	0.0308	POR/RDH10/EGR1/TNF/HIF1A/PAX8/IL1B/PPARGC1A/ARNT/IFNG/HPN	11
BP	GO:0032988	ribonucleoprotein complex disassembly	11/7096	15/18670	0.00594	0.04131	0.0308	KLC1/MTIF2/EIF2D/DHX8/MCTS1/GFM2/DYRK3/MTIF3/KIF5B/VCP/MRRF	11
BP	GO:0042762	regulation of sulfur metabolic process	11/7096	15/18670	0.00594	0.04131	0.0308	PDK4/SLC7A11/PDK2/GSTZ1/BHMT/PDK1/NFE2L2/PDP2/PDP1/SNCA/PDPR	11
BP	GO:0043101	purine-containing compound salvage	11/7096	15/18670	0.00594	0.04131	0.0308	PNP/DGUOK/ADK/PRTFDC1/MTAP/GMPR2/AMPD2/ADA/DCK/AMPD3/ADAL	11
BP	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly	11/7096	15/18670	0.00594	0.04131	0.0308	DR1/THRA/PSMC4/HMGB1/CREB1/PSMC3/CAND1/PSMC6/PSMC5/PSMC2/WNT10B	11
BP	GO:0051198	negative regulation of coenzyme metabolic process	11/7096	15/18670	0.00594	0.04131	0.0308	CBFA2T3/FBP1/STAT3/NUPR1/PPARGC1A/SLC25A12/MYOG/PFKFB1/HDAC4/DDIT4/PPARA	11
BP	GO:0071025	RNA surveillance	11/7096	15/18670	0.00594	0.04131	0.0308	XRN1/EXOSC2/EXOSC7/SUPV3L1/DXO/EXOSC9/EXOSC3/PCID2/EXOSC6/EXOSC8/EXOSC5	11
BP	GO:2000484	positive regulation of interleukin-8 secretion	11/7096	15/18670	0.00594	0.04131	0.0308	TLR1/TLR2/WNT5A/CD58/FCN1/CD2/FFAR2/HYAL2/LGALS9/F2R/CD244	11
BP	GO:0017157	regulation of exocytosis	101/7096	217/18670	0.006011	0.04176	0.03113	ITGAM/CCR2/APBA1/STAM/RAB9A/RAC2/ANXA1/LYN/ATP6AP1/RAP1B/SYT11/IL4R/STXBP5/LAMP1/HMOX1/C12orf4/GSK3B/MICAL1/STXBP1/UNC13B/PTAFR/STXBP2/HLA-F/FBXL20/FGR/ABR/CDK5/RAB3GAP1/DTNBP1/SDCBP/RAP1A/RAB8A/DOC2B/RAB33B/PREPL/LRRK2/SYT6/ADCY1/BCR/ARF1/P2RX1/ADORA2B/RPH3AL/VPS18/NAPA/GNAI2/CHMP2A/TSG101/UNC13D/RAB5A/SYTL4/HGS/CD300A/LGALS9/HYAL3/VPS4B/FER/RABGEF1/CAMK2A/CHRM2/DNM1L/CHRNA4/CDK5R2/CLASP2/RAB8B/SYT13/ATP2A2/DVL1/AP1G1/FMR1/IL13RA2/RAB3A/CHRNB2/P2RY4/PRAM1/SYT9/PLA2G6/CD84/IFNG/SYT1/RAB3B/IL1RAPL1/SNX4/SYT2/VAMP1/STXBP3/DOC2A/SYT4/CADPS2/SYT5/SCAMP5/RAB3D/SNCA/RIMS2/FOXF1/WNT7A/CACNA1H/RAB27A/RAB26/P2RY1/LGI3	101
BP	GO:0006308	DNA catabolic process	24/7096	41/18670	0.006044	0.04194	0.03127	AIFM1/DNASE2B/ISG20/XRN2/SETMAR/CASP3/NMNAT1/DFFA/HMGB1/DNASE1/IL6/ATM/DICER1/BAX/HMGB2/ST20/DNASE1L2/ERI3/KPNA1/REXO4/KPNB1/ENDOG/DNASE2/MIR146A	24
BP	GO:0042594	response to starvation	90/7096	191/18670	0.006072	0.04209	0.03138	PDK4/UPP1/CDKN1A/ATG7/ZFP36/SRD5A1/KLF10/LRP11/HMGCL/PMAIP1/GAS2L1/ULK2/SIK1/ATG14/LAMP2/FAS/HFE/AKR1C3/TBC1D5/ATF4/WDR24/HIGD1A/AACS/XPR1/MAP1LC3A/SEH1L/PCK2/HSPA5/HNRNPA1/PPM1D/SIK2/RRAGD/WIPI1/NPRL3/SIRT1/EIF2S1/KPTN/LRRK2/PPARGC1A/MAP1LC3C/OXCT1/FNIP1/ZFYVE1/MYBBP1A/MAPK8/PFKFB1/BCL2/BCAS3/ASNS/WDR45B/CTSV/FOXK2/TNRC6A/SREBF2/MAP3K5/RRAGA/NFE2L2/IMPACT/EIF2AK2/ULK1/DSC2/ITFG2/SESN1/PRKAA1/DNAJC15/HAMP/MAPK1/MTMR3/SH3GLB1/EIF2AK1/NPRL2/DAP/EIF2A/CAD/TBL2/GNPAT/DAPL1/GABARAPL1/CLEC16A/WNT2B/EIF2AK4/CADPS2/MTOR/PICK1/DEPDC5/SESN2/UCN3/FOXO3/ALB/BMPR2	90
BP	GO:1902750	negative regulation of cell cycle G2/M phase transition	53/7096	105/18670	0.006081	0.04211	0.03139	PSMB9/CUL1/PSMB8/HUS1B/ATF5/PSMA5/PSMD11/PSME1/GPR132/TAOK3/ZNF830/PSMB10/PSMA1/PSMA4/UIMC1/SYF2/PSMB1/PSMC4/DONSON/PSMD13/PSMB3/PSMB5/PSMD6/ATM/PSMC3/PSME3/RAD17/PSMC6/FHL1/FOXO4/TICRR/MIIP/DTL/BRCA1/PSMC1/CLSPN/PSMD8/PSMA2/FBXL7/TOPBP1/PSMC5/PSMC2/PSMB2/PSMD4/AURKA/BRSK1/RBX1/BRCC3/PSMD1/PSMB4/ZFYVE19/PSMD9/PSMD3	53
BP	GO:0010332	response to gamma radiation	31/7096	56/18670	0.006154	0.04257	0.03173	CDKN1A/MYC/PTPRC/EGR1/CXCL10/ERCC6/TRIM13/TMEM109/HSPA5/HRAS/XRCC5/PML/CCL7/ATM/POLG/BCL2/BAX/TSPYL5/CYBA/LIG4/ZMPSTE24/ATR/PRKAA1/MDM2/XRCC6/DCUN1D3/FANCD2/MEN1/POLB/GPX1/BAK1	31
BP	GO:0007162	negative regulation of cell adhesion	131/7096	289/18670	0.006174	0.04262	0.03178	KLF4/MYADM/PTPN6/LILRB2/DUSP1/ANXA1/MAD2L2/IRF1/GBP1/ARG2/GPNMB/PTPN2/TNFRSF14/BCL6/LPXN/SMAD7/MBP/FGL2/ACTN4/IL4R/CEBPB/RGCC/CBFB/JAK2/PTPRC/HFE/CD74/ARHGDIA/TNFRSF21/FXYD5/LILRB1/CXCL12/PTPRO/DUSP3/PLXNB2/TGFB1/RDX/CYP1B1/GTPBP4/SOCS5/MAPK7/PLXNC1/SWAP70/PRKCD/ADAM15/METTL3/IL20RB/PTPN22/ZBTB7B/SOCS6/BMP2/ARHGDIB/VEGFA/DTX1/CASP3/ABL1/IDO1/NFKBID/MMP12/SEMA4D/LRP1/HMGB1/IL1RN/PPM1F/HLA-G/CTLA4/CBLL1/GLMN/PTK2/ARHGAP6/TIGIT/VSIG4/MUC1/PLXNA1/AKNA/SCGB1A1/PDCD1LG2/NRARP/PLXND1/ZNF703/BMP4/SERPINE1/BCAS3/ADAMDEC1/KANK1/LGALS1/LAG3/ADAM22/DAB1/CD300A/CD274/LGALS9/LAX1/SEMA5A/BTN2A2/MMP14/DMTN/CORO1C/HLX/CDSN/CLASP2/PPARA/RCC2/FZD4/TNFSF4/WNT1/PAG1/APOA1/SOCS1/HAVCR2/PLXNA3/SPOCK1/HRG/GCNT2/MAP2K5/FZD7/TACSTD2/PLXNA2/MEN1/CD80/TGFBI/MAP4K4/TBX21/RHOA/TRPV4/CX3CL1/ITGB1BP1/HOXA7/TWSG1/ERBB3/MIR146A	131
BP	GO:0038093	Fc receptor signaling pathway	111/7096	241/18670	0.006175	0.04262	0.03178	MYO1G/FCGR1B/FOS/FYN/APPL2/BCL10/LYN/FCGR1A/CLEC4D/HCK/PSMB9/CUL1/CLEC4E/PSMB8/PTPRC/PSMA5/PSMD11/NFKB1/PSME1/ACTR2/LCP2/RELA/ACTB/PPP3CB/NFATC3/LAT2/PAK1/PSMB10/PSMA1/PSMA4/PRKCD/TAB3/TRAF6/IKBKG/BAIAP2/FGR/NCK1/CYFIP2/ABL1/PSMB1/PAK2/PSMC4/ARPC1A/PLCG2/RAP1A/SHC1/PSMD13/CRK/PSMB3/RAC1/ARPC1B/ITK/CD200R1/CYFIP1/MYO1C/PSMB5/PTK2/PSMD6/PSMC3/FCER1A/MAPK8/TAB1/PSME3/WIPF2/NFATC1/CD247/PSMC6/NFATC2/CD47/TEC/CD3G/GRB2/FER/ACTR3/ELMO1/VAV1/PLD2/MAPK1/PSMC1/MAP2K4/PLA2G6/ARPC4/MYO10/PSMD8/PSMA2/NR4A3/MAP3K1/HSP90AB1/FCGR2A/MYH2/PSMC5/WIPF1/ARPC2/PSMC2/PSMB2/PSMD4/PRKCQ/MALT1/CHUK/PSMD1/WAS/APPL1/PSMB4/PSMD9/NCKAP1/PSMD3/LAT/ELMO2/PIK3CB/PTPRJ/MAPK9	111
BP	GO:0071166	ribonucleoprotein complex localization	63/7096	128/18670	0.006181	0.04262	0.03178	TSC1/NXF1/SRSF5/NUP62/NUP160/CHTOP/NUP214/ENY2/AGFG1/RAN/ALYREF/RNPS1/EIF6/MAGOHB/SARNP/NUP85/NXT1/SEH1L/YTHDC1/NUP43/NPM1/HNRNPA2B1/RBM8A/FYTTD1/DDX19B/U2AF1/POM121/ZNF593/SRSF3/SYMPK/XPOT/CPSF3/FIP1L1/NUP88/THOC2/SRSF6/SRSF7/NUP107/CDC40/THOC5/POLR2D/PRPF31/U2AF1L4/EIF5A/NUP93/LTV1/THOC6/RIOK2/SSB/SRRM1/NUP205/SRSF4/EIF4E/NUP50/DHX38/MCM3AP/PCID2/CPSF2/CPSF1/RRS1/POM121C/AAAS/UPF1	63
BP	GO:0060491	regulation of cell projection assembly	84/7096	177/18670	0.006227	0.04289	0.03198	CDC42EP4/RAC2/DPYSL3/ARF6/ATG3/DNM3/ARAP1/KLHL41/P2RX7/KCTD17/PLD1/EVL/TWF2/PLEK2/RDX/PFN1/CDC42EP2/MAP4/PRKCD/SRF/RHOG/FUZ/HRAS/SRGAP2C/FAM98A/P2RY12/ATP8B1/PPP1R16B/TRPM2/RAC1/PLEKHM1/CCDC88A/CDC42EP3/CYLD/CYFIP1/ADAMTS16/SH3YL1/BBS4/SYNE2/MAK/NRP1/DNM2/WDPCP/BCAS3/HDAC4/RHOQ/RAB5A/KANK1/KLF5/DYNC2LI1/NDEL1/TBC1D7/FER/CCDC151/DMTN/CORO1C/RCC2/BIN3/DOCK11/SLIT2/FSCN1/WNT1/FMR1/TCHP/IFT20/MYO10/TGFB3/ATP7A/HRG/MIEN1/TACSTD2/ARPC2/EPS8L2/CEP120/VDAC3/MTOR/CCL19/CCR7/WAS/TENM2/RP1/NCKAP1/WRAP73/ZMYND8	84
BP	GO:0002690	positive regulation of leukocyte chemotaxis	45/7096	87/18670	0.006243	0.04291	0.03199	FPR2/CCR2/RAC2/OXSR1/WNT5A/VEGFB/CAMK1D/LGMN/PLA2G7/CD74/CXCL10/CXCL12/PTK2B/SWAP70/CXCL13/VEGFA/CMKLR1/AIF1/CCL5/HMGB1/CCL7/RAC1/IL6/C3AR1/MOSPD2/GPSM3/ZNF580/TMEM102/SERPINE1/CCR6/CREB3/LGALS9/CALR/C1QBP/CXCR2/ADAM17/LBP/TRPV4/DAPK2/CCL19/TIRAP/CCL4/CCR7/IL23A/S100A14	45
BP	GO:0009060	aerobic respiration	45/7096	87/18670	0.006243	0.04291	0.03199	CBFA2T3/MDH1/UQCRC2/PANK2/HIF1A/CAT/ME3/OGDH/IDH1/UQCR10/ACO1/COX7C/IDH2/COX7A2L/DHTKD1/NDUFA4/MTFR1L/SHMT2/COX4I2/FH/MDH1B/OXA1L/COX15/PDHB/IREB2/SUCLG2/BLOC1S1/DLAT/IDH3A/PDHA2/SURF1/FAHD1/SDHA/VCP/NDUFS7/ND4/SDHD/ME2/IDH3G/UQCRB/SDHAF2/COX6C/MTFR2/NNT/COX7B	45
BP	GO:0030488	tRNA methylation	23/7096	39/18670	0.0063	0.04303	0.03208	TRMT6/FTSJ1/TRMT5/TRMT1/TYW3/BCDIN3D/LCMT2/TRMT112/TRMT61B/NSUN2/TRMT1L/METTL1/METTL8/HSD17B10/WDR4/ALKBH8/THUMPD2/TRMT11/THUMPD3/MTO1/TRMT10C/GTPBP3/NSUN6	23
BP	GO:0072529	pyrimidine-containing compound catabolic process	23/7096	39/18670	0.0063	0.04303	0.03208	TYMP/UPP1/ALDH6A1/TET2/NEIL2/UNG/NT5C/CDADC1/DPYD/APOBEC3G/TDG/APOBEC3C/APOBEC2/APOBEC3B/CDA/DCTPP1/NT5C3A/NT5M/UPP2/DUT/MBD4/TET1/SMUG1	23
BP	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	23/7096	39/18670	0.0063	0.04303	0.03208	ITPRIP/PEA15/TNFRSF10A/TNFAIP3/FAS/HMOX1/HGF/TNFSF10/CASP8/ARHGEF2/TRADD/RAF1/BMP5/SERPINE1/HMGB2/RFFL/TNFRSF10B/BRCA1/FADD/TRAF2/FAIM2/GPX1/FAIM	23
BP	GO:0051817	modification of morphology or physiology of other organism involved in symbiotic interaction	56/7096	112/18670	0.006306	0.04303	0.03208	RAB9A/SERPINB9/ATG7/AZU1/GAPDH/CHD1/APOE/TGFB1/INSR/PTX3/HYAL2/NAPEPLD/KPNA4/TFAP4/IFI27/CD209/IGF2R/CASP8/TAF11/CCL5/VAPB/CTDP1/PSMC3/BCL2L11/RXRA/CCL8/TBC1D20/TNIP1/INPP5K/CCNK/CFL1/TYMS/RRAGA/EIF2AK2/ANXA2P2/FMR1/FBXL2/KPNA1/BAD/SMC3/CD4/CTSG/EIF2AK4/PC/CSF1R/ANXA2/HPN/CCNT1/DAG1/KPNB1/CCL4/PPIB/NUCKS1/TARDBP/APCS/CXCL6	56
BP	GO:1903828	negative regulation of cellular protein localization	56/7096	112/18670	0.006306	0.04303	0.03208	ARF6/CSK/GBP1/BARD1/CHP1/SIRT4/ABHD17C/GSK3B/TGFB1/SIN3A/RAB23/CD36/LILRB4/FZD9/TP53INP2/UBXN2B/GOPC/CDK5/SP100/SAPCD2/GDI1/NUMB/NSFL1C/UBE2J1/MDFIC/MFHAS1/UBE2G2/SNX33/LRRK2/FLCN/DCLK2/INPP5K/RHOQ/LMAN1/DMTN/DERL2/FBXO4/COMMD1/INSIG1/TXN/YOD1/CAV3/TRIM29/MAP1A/ASTN2/PID1/CLDN18/DNAJA1/PKIA/AP2M1/ITGB1BP1/TTBK2/PICALM/ROCK2/ERLEC1/OS9	56
BP	GO:0019748	secondary metabolic process	36/7096	67/18670	0.006307	0.04303	0.03208	WNT5A/CBR4/AKR1B1/ACAA1/SLC7A11/AKR1C3/ZEB2/AKR7A2/PGAM1/CYP1B1/AKR7A3/RAPGEF2/MYO5A/AKR1A1/AKR1C1/ETHE1/ASIP/BDH2/PAM/CYP2D6/CYP1A2/BCL2/MPST/CTH/AS3MT/ARL1/AKR1B10/NFE2L2/DCT/CDH3/FMO2/OCA2/CYP2W1/CYP2A6/APPL1/CTNS	36
BP	GO:1903391	regulation of adherens junction organization	36/7096	67/18670	0.006307	0.04303	0.03208	S100A10/ARF6/TSC1/LDB1/SLC9A1/DUSP3/PEAK1/RDX/VEGFA/ABL1/IQSEC1/LRP1/PPM1F/SLK/RAC1/MAPRE2/PTK2/ARHGAP6/LIMCH1/NRP1/WDPCP/BCAS3/MMP14/DMTN/CORO1C/CLASP2/RCC2/HRG/MAP4K4/RHOA/LIMS1/ITGB1BP1/ROCK2/MACF1/PTPRJ/FMN1	36
BP	GO:0009451	RNA modification	78/7096	163/18670	0.006326	0.04311	0.03214	TRMT6/SEPHS2/JMJD6/DPH3/MEPCE/ALKBH1/FTSJ1/TPRKB/OSGEPL1/ELP4/METTL14/TRMT5/TRMT1/TYW3/METTL3/NAF1/TFB1M/ADARB1/BCDIN3D/DUS2/LCMT2/TRMT112/PUS7L/TRMT61B/RPUSD2/NSUN2/APOBEC3G/TRMT1L/PUS1/APOBEC3C/NAT10/CBLL1/OSGEP/THUMPD1/FBL/APOBEC2/FTO/NHP2/METTL1/ELP3/METTL8/HSD17B10/GAR1/FTSJ3/FDXACB1/QTRT1/DIMT1/CMTR1/ZCCHC4/WDR4/ALKBH8/THUMPD2/MOCS3/TRMT11/TGS1/METTL15/RBM47/THUMPD3/SSB/APOBEC3B/ELP2/MRM1/RPUSD3/MTFMT/FBLL1/NSUN5P1/CMTR2/ADAT2/MTO1/DUS1L/TRMT10C/ADAR/PUS7/GTPBP3/NUDT16/NSUN6/NOP10/AARS2	78
BP	GO:2000058	regulation of ubiquitin-dependent protein catabolic process	72/7096	149/18670	0.006347	0.04317	0.03218	CBFA2T3/SMAD7/KEAP1/DDRGK1/FBXW7/RNF139/BCAP31/HFE/RAD23B/FHIT/RYBP/GSK3B/MAGEF1/RNF19B/CSNK2A2/UBE3A/UBE2K/SGTA/ZFAND2A/SOCS5/PTK2B/CSNK1D/LATS1/RNF217/CEBPA/PLK2/ANKIB1/GCLC/SDCBP/ARAF/PML/CLU/UCHL5/LRRK2/SUMO1/GLMN/PTK2/HSPBP1/CSNK1A1/CSNK1E/ARIH2/PLK3/DISC1/UBQLN2/TRIB2/BBS7/DET1/NKD2/KLHL40/STUB1/NFE2L2/COMMD1/CAV3/USP7/DVL1/MAP1A/WNT1/PSEN1/MDM2/UBXN1/OGT/HSP90AB1/CLEC16A/FOXF2/VCP/AURKA/RBX1/BAG5/SMARCC1/CHFR/WNT10B/MAPK9	72
BP	GO:0016573	histone acetylation	75/7096	156/18670	0.006348	0.04317	0.03218	SPI1/BAZ1A/DR1/LDB1/MORF4L2/HAT1/SUPT7L/KAT2B/MRGBP/TRIM16/TGFB1/SIN3A/ZNF451/JADE3/ARRB1/NCOA3/PCGF2/RUVBL2/RUVBL1/EPC2/MBIP/MSL3/MBD3/KAT7/YEATS4/SETD5/TAF5L/IL1B/KAT8/TAF12/CRTC2/SIRT1/NAA40/BRD8/TAF5/PPARGC1A/FLCN/MCRS1/MUC1/KAT5/ELP3/BRPF1/NOC2L/DPF2/CTCF/RSF1/PHF20/ZMPSTE24/TAF6L/BRCA1/ING3/KANSL1L/CLOCK/EPC1/KAT2A/PHF10/CPA4/TAF9B/EID1/OGT/MCM3AP/ING4/SET/JADE1/USP22/SNCA/MSL1/POLE4/TADA3/PAXIP1/ACTL6A/KAT6B/WDR5/TAF7/NAA60	75
BP	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	100/7096	215/18670	0.006395	0.04344	0.03239	KLF4/S100A9/S100A8/SERPINB9/CDKN2D/CLEC7A/BCL10/POR/AIFM1/GRAMD4/CTSD/PTGS2/NLRP3/TNFRSF10A/SH3RF1/PMAIP1/RPS6KA3/BIRC2/CD44/MYC/NLRP12/JAK2/LAMP3/FAS/BCAP31/TNF/IFT57/MICAL1/HGF/ARL6IP1/FIS1/ARRB1/TFAP4/HTRA2/VEGFA/SFN/TNFSF10/CASP8/PAK2/DAPK1/PML/CASP5/HMGB1/TRADD/RAF1/PPM1F/SIRT1/LCK/PLAUR/EGLN3/DNAJB6/PDCD5/DDX3X/PRR7/FNIP1/BCL2L11/P2RX1/MMP9/BAX/CRADD/BIRC3/CASP1/KHDC1/LGALS9/RFFL/ST20/BIRC7/MAP3K5/F2R/LAMTOR5/CAAP1/TNFRSF10B/MUL1/FADD/TRAF2/CASP4/MDM2/YWHAE/COL4A3/BAD/DAP/NLRP1/IGBP1/ST18/MAP2K5/NLRP2/WDR35/DIABLO/F3/GPX1/VCP/RHOA/TRIAP1/SNCA/MALT1/BAK1/XIAP/MGMT/SIAH2/SOX7	100
BP	GO:0006457	protein folding	105/7096	227/18670	0.006494	0.04407	0.03286	GRN/HSPA6/EMC3/ERP29/NFYC/GNAI3/CDC37L1/LMAN2L/GNB1/GNB2/DNAJA4/RAD23B/PDCL/ERP27/CD74/EMC2/PDIA3/PPIL1/CSNK2A2/CDC37/PDRG1/DNAJB1/SGTA/CRTAP/CLPX/WFS1/HSPB1/RUVBL2/HSPA5/DNAJC19/FKBP5/DNAJC2/RP2/DFFA/DNAJB5/ERP44/CSNK2B/CLU/GRPEL1/MKKS/TOR1B/GNG2/DNAJC1/DNAJB6/GNB3/PDCD5/PTGES3/HSPBP1/DNAJC7/DNAJB4/TOR1A/SPHK1/PDIA6/GRPEL2/TBCEL/GNAI2/ALG12/PFDN4/FKBP9/DNAJC4/GANAB/DNAJC10/DERL1/MLEC/PEX19/LMAN1/NGLY1/CCT4/GNB4/CANX/SUCO/CALR/HSPA1L/MOGS/CCT8/TBCC/VBP1/TBCA/BAG2/HSP90B1/CHORDC1/PPIC/PSMC1/LTBP4/UBXN1/DNAJA1/HSP90AB1/EMC1/NUDCD2/PFDN5/HSPB6/PDILT/TBCE/VCP/ENGASE/BAG5/ST13/UNC45B/PPIB/DNAJC24/DNAJC18/NUDC/APCS/PFDN1/AIP	105
BP	GO:0044782	cilium organization	170/7096	384/18670	0.006503	0.04409	0.03287	ARMC9/PRKAR2B/TMEM138/TUBA1A/NINL/ATG3/RILPL1/HYLS1/BBS5/TCTN1/RAB11A/FLNA/RFX2/SNX10/TTC8/FOPNL/LRRC6/IFT172/ODF2/KCTD17/TNPO1/PKD2/IFT57/HAUS8/ACTR2/BBS10/CNTRL/KIF3B/RAB23/KIFAP3/CEP164/MAP4/PCM1/DYNLL2/CSNK1D/ARL13B/WDR11/CEP131/CBY1/IFT80/FUZ/SPAG1/SFI1/PAFAH1B1/CDK5RAP2/C5orf30/WDR19/INTU/CEP76/MAPRE1/EHD1/BBS2/BBS12/RAB8A/RFX3/GORAB/MKKS/IFT46/CCDC88A/TTC39C/OCRL/RPGR/DNAL1/CYLD/IFT52/ADAMTS16/ATP6V1D/B9D1/BBS4/CSNK1E/TCTN2/SYNE2/HAUS2/PLA2G3/NPHP4/MAK/ABLIM3/DISC1/HSPB11/DNM2/AVIL/WDPCP/DNAI2/UBXN10/KIF24/PRKACA/CKAP5/DCTN2/DNAAF2/DYNC2LI1/CEP152/TUBA4A/RSPH9/BBS7/TTC17/TBC1D7/MKS1/TTLL3/CCDC151/DYNLRB1/CCDC65/DYNLRB2/ACTR3/CEP63/KIF27/E2F4/LCA5/FAM161A/CEP57/CETN2/RSPH6A/HAUS5/TUBB4A/PIH1D3/HAUS1/BBS9/TMEM231/CEP19/TCHP/PTPDC1/IFT20/YWHAE/CEP83/TTLL1/DNAI1/KIF17/TPGS1/WDR60/TMEM80/FAM161B/FGFR1OP/UNC119B/CCDC13/PKHD1/EHD3/IFT22/ATXN10/WDR35/YWHAG/LRRC61/ABCC4/TRAF3IP1/SNAP29/TCTN3/CEP120/DZIP1L/CCDC28B/VDAC3/TEKT3/TTBK2/TMEM107/CEP78/IFT74/CCDC63/ASAP1/NEK8/SPAG17/CCDC66/UBE2B/DNAH8/TTC30B/IFT81/RP1/POC1B/C2CD3/ALMS1/GAS8/WRAP73/SPATA6/ABLIM1	170
BP	GO:0021587	cerebellum morphogenesis	22/7096	37/18670	0.006549	0.04416	0.03292	DLL1/MAP2K1/LDB1/HSPA5/CDK5/ABL1/OPHN1/XRCC1/DAB1/WNT1/CBLN1/RORA/GNPAT/FAIM2/ATP7A/SPTBN2/KNDC1/TRNP1/WNT7A/AGTPBP1/SMO/KIF14	22
BP	GO:0050851	antigen receptor-mediated signaling pathway	142/7096	316/18670	0.00655	0.04416	0.03292	SH2B2/FYN/EZR/KCNN4/NFKBIZ/PTPN6/BCL10/LYN/CSK/GBP1/MNDA/PTPN2/PSMB9/CUL1/LPXN/PLEKHA1/PSMB8/BTN2A1/CBFB/PTPRC/UBE2N/PSMA5/PSMD11/TNFRSF21/NFKB1/PSME1/DUSP3/LCP2/CD22/RELA/DENND1B/CD226/LAT2/PAK1/PSMB10/PSMA1/PSMA4/LILRB4/TRAF6/IKBKG/EIF2B5/PTPN22/HLA-DPB1/HLA-DPA1/NCK1/PDE4B/HRAS/ABL1/SLC39A10/NFKBID/PSMB1/PAK2/PSMC4/THEMIS2/CD3D/PLCG2/PSMD13/ICOSLG/TRAC/PSMB3/RBCK1/TESPA1/RAB29/ELF1/TRBC1/ITK/LCK/HLA-DRA/CYLD/CTLA4/PSMB5/PSMD6/MIR34A/BTN3A2/PSMC3/TRAT1/PSME3/BCL2/PRKD2/BAX/CD247/PSMC6/NFATC2/PIK3CD/MS4A1/TEC/BTN3A3/CD3G/CD300A/LAX1/GCSAM/BTN2A2/ADA/THEMIS/CD276/NFAM1/PSEN1/BTN3A1/MAPK1/HLA-DQB2/PAG1/PSMC1/PRAM1/EIF2B1/PSMD8/PSMA2/PLCL2/SKAP1/TXK/CD4/EIF2B3/CACNB3/PSMC5/SLA2/PSMC2/PSMB2/PSMD4/PRKCQ/FOXP1/LIME1/PAX5/MALT1/CHUK/PSMD1/CCR7/WAS/EIF2B2/CD3E/PSMB4/CMTM3/CACNA1F/PSMD9/UBASH3A/MOG/PSMD3/LAT/IGHD/MEF2C/PIK3CB/PTPRJ/RFTN1/PHPT1	142
BP	GO:0051402	neuron apoptotic process	110/7096	239/18670	0.006558	0.04416	0.03292	NQO1/ITGAM/FYN/CX3CR1/GRN/NR4A2/PINK1/GCLM/AIFM1/SOD1/GAPDH/ALKBH1/SIAH1/FBXW7/LGMN/CEBPB/JAK2/ADAM8/TNF/HMOX1/TNFRSF21/NUPR1/KRAS/APOE/BTG2/ATF4/AXL/STXBP1/FIS1/ARRB1/HIF1A/WFS1/PTK2B/CORO1A/MCL1/ITSN1/FZD9/ADARB1/HSPA5/CDK5/CASP3/HRAS/NMNAT1/GCLC/CTSZ/ZPR1/CLN3/MAP3K12/SRPK2/LRP1/TYROBP/G6PD/EGLN3/PPARGC1A/ATM/SNX6/BCL2L11/NRP1/BCL2/KDM2B/BAX/HDAC4/CASP2/CLCF1/SYNGAP1/AKT1S1/MAP3K11/UNC5B/PITX3/LIG4/BHLHB9/F2R/NSMF/CNTF/FADD/PSEN1/UBE2M/CNTFR/STAMBP/MAP2K4/POU4F3/TGFB3/NLRP1/PIGT/FAIM2/NR4A3/HYOU1/PIN1/HSP90AB1/RB1/LANCL1/SET/DIABLO/TERT/POLB/RHOA/TYRO3/APP/SNCA/CX3CL1/SIGMAR1/PTPRZ1/SLC30A10/ERBB3/KIF14/FOXO3/NTRK2/MEF2C/OXR1/GDF5	110
BP	GO:2000116	regulation of cysteine-type endopeptidase activity	110/7096	239/18670	0.006558	0.04416	0.03292	KLF4/S100A9/S100A8/FYN/SERPINB9/CDKN2D/CLEC7A/BCL10/POR/AIFM1/GRAMD4/CTSD/PTGS2/PSMB9/NLRP3/TNFRSF10A/SH3RF1/PMAIP1/RPS6KA3/BIRC2/LGMN/CD44/MYC/NLRP12/JAK2/LAMP3/FAS/BCAP31/TNF/IFT57/AIM2/MICAL1/HGF/ARL6IP1/FIS1/ARRB1/CAST/TFAP4/HTRA2/VEGFA/SFN/CYFIP2/TNFSF10/CASP8/PAK2/DAPK1/PML/CASP5/HMGB1/TRADD/RAF1/PPM1F/SIRT1/TTBK1/LCK/PLAUR/EGLN3/DNAJB6/PDCD5/DDX3X/CST7/PRR7/FNIP1/BCL2L11/P2RX1/MMP9/MEFV/BAX/CRADD/BIRC3/CASP1/KHDC1/LGALS9/RFFL/ST20/BIRC7/MAP3K5/F2R/LAMTOR5/CAAP1/TNFRSF10B/MUL1/FADD/TRAF2/CASP4/MDM2/YWHAE/COL4A3/BAD/DAP/NLRP1/IGBP1/ST18/PCID2/MAP2K5/NLRP2/WDR35/DIABLO/F3/GPX1/VCP/RHOA/TRIAP1/SNCA/MALT1/BAK1/XIAP/MGMT/SIAH2/SOX7	110
BP	GO:0002418	immune response to tumor cell	12/7096	17/18670	0.006582	0.04416	0.03292	CD226/ADAM15/FBXO38/HMGB1/PVR/CD274/CRTAM/PRF1/HAVCR2/HRG/IL12B/MICA	12
BP	GO:0006750	glutathione biosynthetic process	12/7096	17/18670	0.006582	0.04416	0.03292	GCLM/MGST2/SLC7A11/GGCT/GCLC/HAGH/GSS/CNDP2/NFE2L2/GGT7/GGT5/CHAC2	12
BP	GO:0009129	pyrimidine nucleoside monophosphate metabolic process	12/7096	17/18670	0.006582	0.04416	0.03292	UPP1/CDADC1/CMPK1/TYMS/SHMT1/UCK1/DCTD/CAD/UCKL1/NT5M/UPP2/DUT	12
BP	GO:0032740	positive regulation of interleukin-17 production	12/7096	17/18670	0.006582	0.04416	0.03292	MYD88/NOD2/LY9/IL15/TGFB1/IL6/SPHK1/OSM/IL18/IL12B/PRKCQ/IL23A	12
BP	GO:0060263	regulation of respiratory burst	12/7096	17/18670	0.006582	0.04416	0.03292	RAC2/CLEC7A/GRN/DUSP10/CAMK1D/INSR/RAC1/NOXA1/BCR/RPS19/LBP/SLAMF8	12
BP	GO:2001267	regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	12/7096	17/18670	0.006582	0.04416	0.03292	JAK2/FAS/TFAP4/HTRA2/CASP8/PLAUR/PRR7/MMP9/BAX/LGALS9/CAAP1/ST18	12
BP	GO:0045787	positive regulation of cell cycle	172/7096	389/18670	0.006597	0.04421	0.03296	IGF1/TRIM32/ANXA1/CDKN1A/WNT5A/CCND3/NUP62/RAB11A/MEPCE/MIF/DYNC1LI1/DDRGK1/LFNG/LGMN/RGCC/EZH2/LSM11/PAF1/PKD2/BTG2/CCND2/TMOD3/DUSP3/LRP5/ZNF268/CCPG1/PSRC1/CDK4/KIF3B/TGFB1/RDX/SMC5/SIN3A/MTA3/INSR/FLT3LG/TFAP4/DBF4B/FZD9/UBXN2B/SETMAR/PLK2/SVIL/SFN/NPM1/ABL1/PAFAH1B1/RAD51B/IL1B/AIF1/NSMCE2/PTK6/NSFL1C/RAB11FIP4/SRPK2/PGGT1B/PML/PHIP/SPAG5/HMGN5/SFPQ/CCND1/PDGFB/CDK9/RHNO1/CITED2/TAL1/UHRF2/ESPL1/DDX3X/ATM/TNKS1BP1/MIR34A/ANAPC5/GDPD5/MUC1/SPHK1/KMT2E/MYOG/BCL2L11/PLK3/MYBBP1A/UBE2E2/TRIM21/CCNE1/NDC80/PCNA/BAX/ANKRD17/CRADD/ID2/CASP2/ASNS/CDKN1B/CCNK/KIF20B/PRKACA/CNOT4/IL1A/CDC25A/PLAGL1/GEN1/ARID3A/NUSAP1/VPS4B/FOXO4/EVI2B/UBE2C/HES1/THOC5/DTL/CALR/CDK5R2/MED25/DYNLT3/DYRK3/E2F4/PLCB1/BRCA1/EGFR/CNOT7/GML/CCNY/GPSM2/PKN2/ADAM17/RCC2/MDM2/DLGAP5/EIF4G1/ANAPC4/CCNYL1/RBL2/MTBP/FOSL1/EIF4E/NR4A3/CUL4B/PCID2/HSP90AB1/RB1/PPP2R5B/CNOT10/CARM1/MSX1/TERT/NR2E1/CEP120/ANKRD31/CCNT1/RHOA/TRIAP1/AURKA/ANAPC11/APP/USP22/CDC73/SOX4/CCNYL2/USP19/CSPP1/PRMT1/NUDT16/ATAD5/ROCK2/UBE2B/WNT10B/STXBP4/PRKCA/FEN1/KIF14/E2F8	172
BP	GO:0060326	cell chemotaxis	137/7096	304/18670	0.006633	0.04441	0.03311	S100A9/S100A8/FPR2/S100A12/CCR2/CX3CR1/RAC2/DUSP1/ANXA1/BST1/LYN/OXSR1/WNT5A/AZU1/EGR3/IL17RA/FLT1/VEGFB/CAMK1D/S1PR1/MIF/PPBP/ACKR3/LGMN/CXCL9/PLA2G7/GSTP1/CXCL11/ADAM8/CD74/CXCL10/GAB1/CXCL12/PTPRO/MPP1/NUP85/HGF/FFAR2/HSPB1/PTK2B/SWAP70/PRKCD/CORO1A/RHOG/CXCL13/VEGFA/PDE4B/CMKLR1/IL1B/AIF1/CCL5/HMGB1/TNFRSF11A/CRK/CCL7/IL1RN/TRPM4/TRPM2/RAC1/CXCR1/IL6/PDGFB/FGF1/IL16/CCR5/CKLF/CORO1B/BIN2/MIR34A/SLC12A2/RPS19/C3AR1/MOSPD2/CCL13/GPSM3/NRP1/ZNF580/TMEM102/PRKD2/CCL8/SERPINE1/HMGB2/PIK3CD/CCR6/GPR18/CH25H/CREB3/CXCR6/CCR4/LGALS9/SEMA5A/CNR2/LPAR1/CALR/MST1/CCR3/C1QBP/VAV1/CXCR2/ADAM17/CCL20/JAM3/PREX1/SLIT2/CCL26/EPHB1/HRG/CSF3R/HBEGF/C10orf99/PIK3CG/LBP/PRKCQ/TRPV4/C5AR2/GPR183/DAPK2/CX3CL1/CXCR3/CCL19/MET/TIRAP/CCL4/CCR7/GREM1/CCL24/ACKR2/HMGB4/CCRL2/SLAMF8/IL23A/IL17RC/CXCL6/PDGFD/ELMO2/S100A14/IL37	137
BP	GO:0006029	proteoglycan metabolic process	48/7096	94/18670	0.00664	0.04441	0.03311	IGF1/HS3ST2/HEXB/VCAN/EXTL2/CHSY1/NDST2/HS2ST1/PPARD/IDS/IMPAD1/EXT2/EXT1/HEXA/CHST13/FAM20B/ARSB/SGSH/CSGALNACT1/BMP2/CSPG4/CYTL1/XYLT1/CHST11/SLC35D1/B3GALT6/GLCE/IDUA/ADAMTS12/CHST14/SULF2/XYLT2/HPSE/GAL3ST4/NDST1/CSGALNACT2/HS3ST1/SPOCK2/BCAN/HS3ST3B1/COL2A1/TCF7L2/CHST12/B3GAT3/HS3ST6/BMPR1B/CHST7/BMPR2	48
BP	GO:0050772	positive regulation of axonogenesis	44/7096	85/18670	0.006676	0.04456	0.03322	FN1/SKIL/RAB11A/MAP2K1/ARHGDIA/ZEB2/CXCL12/PLXNB2/TWF2/PAK1/MEGF8/PLXNC1/SRF/VEGFA/TNFRSF12A/PAFAH1B1/GDI1/SEMA4D/LRP1/CYFIP1/PLXNA1/NRP1/DISC1/PLXND1/L1CAM/LPAR3/IST1/NDEL1/SEMA5A/AMIGO1/SLIT2/SHOX2/MAP3K13/RUFY3/PLXNA3/TRAK1/PLXNA2/CHODL/RHOA/CRABP2/MACF1/TRPV2/NTRK2/BMPR2	44
BP	GO:1903901	negative regulation of viral life cycle	44/7096	85/18670	0.006676	0.04456	0.03322	TRIM32/FCN1/PLSCR1/OASL/IFITM2/TNF/IFITM1/TRIM13/IFITM3/MORC2/ISG20/PTX3/TRIM26/OAS3/RSAD2/CCL5/SRPK2/PML/ISG15/TRIM11/APOBEC3G/MAVS/APOBEC3C/IFIT5/ILF3/BANF1/ZC3HAV1/TRIM21/CCL8/TNIP1/INPP5K/CCNK/MX1/SETDB1/RNASEL/IFIT1/SRPK1/EIF2AK2/MID2/TRIM15/TRIM6/EIF2AK4/APCS/BTBD17	44
BP	GO:0002548	monocyte chemotaxis	35/7096	65/18670	0.00672	0.0448	0.0334	FPR2/S100A12/CCR2/DUSP1/ANXA1/LYN/FLT1/LGMN/PLA2G7/CXCL10/CXCL12/PTPRO/AIF1/CCL5/HMGB1/TNFRSF11A/CCL7/IL6/PDGFB/RPS19/MOSPD2/CCL13/CCL8/SERPINE1/CREB3/CCL20/SLIT2/CCL26/CX3CL1/CCL19/CCL4/GREM1/CCL24/SLAMF8/S100A14	35
BP	GO:0030522	intracellular receptor signaling pathway	127/7096	280/18670	0.006754	0.04496	0.03352	VDR/NOD2/NR4A2/IRF7/STAT3/PIM1/GPAM/THRA/NCOA4/UBA5/PPARD/TNFAIP3/DDRGK1/BIRC2/ACTN4/YWHAH/CBFB/JAK2/CTBP2/UBE2N/EZH2/DDX60/NFKBIA/SKP2/AKR1C3/RAN/RELA/TRIM68/TRIM16/DHRS3/UBE3A/ZBTB7A/STARD10/PAK1/NCOA3/LEP/NR1H2/TAB3/LATS1/TRAF6/IKBKG/TLR4/DDX58/PTPN22/CASP8/PMEPA1/GRIP1/NR1D2/UBR5/AHR/PML/BUD31/SIRT1/RHOXF1/BRD8/CYLD/PPARGC1A/CITED2/LSM14A/PUM2/CALCOCO1/CREM/ALOX15B/NCOR1/TRIM24/NPLOC4/IFIH1/KAT5/SEC14L1/RXRA/TAB1/CCNE1/NEDD4/ANKRD17/CYP26B1/BIRC3/NR2E3/NR1H3/UFM1/ASXL2/ALPK1/UBC/ARNT/CALR/FABP5/BRCA1/C1QBP/PPARA/GPATCH3/CLOCK/FHL2/RIOK3/GPHB5/TIFA/FAM120B/CYP27B1/RORA/ARNTL/NR4A3/TGFB1I1/STRN3/RNF4/DNAJA1/TRIM15/NLRX1/NR2F1/RB1/CARM1/CYP26A1/SLA2/ESRRB/DDX54/FOXP1/RHOA/TSPAN6/CRABP2/XIAP/TADA3/DCBLD2/ZCCHC3/NRIP1/DAXX/LBH/NR1H4/NR2F6/TAF7/FOXH1	127
BP	GO:0034620	cellular response to unfolded protein	68/7096	140/18670	0.006757	0.04496	0.03352	EXTL2/LMNA/HSPA6/TPP1/PTPN2/TMBIM6/PPP1R15A/CREBRF/FKBP14/ATF4/EDEM1/TLN1/WFS1/SSR1/RNF175/HSPA5/NCK1/HERPUD2/TMEM33/PARP16/CREB3L2/SHC1/WIPI1/VAPB/PPP1R15B/CCND1/EIF2S1/GOSR2/CREB3L4/SERP1/PDIA6/KDELR3/BCL2L11/BAX/CTH/ASNS/DERL1/CREB3/TM7SF3/ACADVL/DNAJB9/CANX/DERL2/STUB1/CALR/HSPA1L/NFE2L2/EIF2AK2/YOD1/CTDSP2/HSP90B1/GFPT1/BFAR/TBL2/HYOU1/PPP2R5B/YIF1A/OPTN/VCP/MBTPS2/ERN1/BAK1/MBTPS1/PREB/DAXX/ARFGAP1/HDGF/ATF6B	68
BP	GO:0042092	type 2 immune response	21/7096	35/18670	0.006786	0.04506	0.03359	NOD2/CCR2/IL27RA/ANXA1/ARG2/STAT6/BCL6/NLRP3/IL4R/BATF/CD74/DENND1B/SOCS5/RSAD2/IDO1/IL6/HLX/IL18/TNFSF4/PRKCZ/TBX21	21
BP	GO:1990774	tumor necrosis factor secretion	21/7096	35/18670	0.006786	0.04506	0.03359	IL27RA/WNT5A/ARG2/SYT11/LILRA5/LILRA2/FRMD8/DDX58/DHX9/HMGB1/MAVS/LRRK2/IFIH1/LGALS9/FZD5/IFNGR1/HAVCR2/IFNG/CX3CL1/NR1H4/GHRL	21
BP	GO:0048167	regulation of synaptic plasticity	88/7096	187/18670	0.006894	0.04573	0.03409	NRGN/CX3CR1/LILRB2/SIPA1L1/PTGS2/RAB11A/ABHD6/YWHAH/LGMN/SQSTM1/EPHB2/KRAS/APOE/GSK3B/TSHZ3/PPP3CB/STXBP1/UNC13B/RAPGEF2/PTK2B/SRF/STAU1/BAIAP2/SCTR/CDK5/PLK2/HRAS/ABL1/RAB3GAP1/S100B/AGER/CREB1/RAB8A/TYROBP/NPTN/EIF4EBP2/EGR2/ARC/CRTC1/ADCY1/ARF1/RGS14/SHISA9/CNTN4/SORCS2/RAB5A/SYNGAP1/SHANK1/CPEB3/CAMK2A/NPAS4/GRIN2C/RASGRF1/NSMF/SLC8A2/MAP1A/KAT2A/PSEN1/FMR1/RAB3A/MAPK1/CBLN1/PPFIA3/CDC20/RIN1/YWHAG/EIF2AK4/NR2E1/SYT4/PRKCZ/RELN/PICK1/BRSK1/APP/SNCA/CX3CL1/SLC24A2/SSH1/RIMS2/SLC8A3/SHISA8/CYP46A1/LZTS1/SHANK3/NTRK2/MEF2C/CAMK2B/SYNPO	88
BP	GO:0009416	response to light stimulus	141/7096	314/18670	0.006927	0.0458	0.03415	CRIP1/FOS/BMF/TRIM32/CDS1/DUSP1/CDKN2D/CDKN1A/NMT2/JUND/BHLHE40/PTGS2/FECH/GNB1/SIK1/MYC/PER2/SLC7A11/ERCC6/KRAS/ERCC4/MAP3K4/HMGCR/ATF4/RELA/UBE4B/HMGCS1/ARRB1/HIF1A/GNAQ/PITPNM1/MAPK13/METTL3/USP28/RUVBL2/ZBTB1/HYAL2/TMEM161A/RBM4/DDB1/RBM4B/CDK5/CAT/CASP3/NPM1/PML/UBE2A/METAP2/CREB1/PDE6G/SIRT1/NPTN/TIPIN/CCND1/EIF2S1/MAP4K3/RHNO1/FBXL3/CRTC1/POLH/ACTR5/TP53I13/NPHP4/POLG/MAPK8/BCL2/DNM2/PCNA/NEDD4/BAX/NOC2L/RGS14/ERCC1/ID2/ASNS/YY1/NR2E3/USP1/CDC25A/OPN3/SYNGAP1/ST20/HYAL3/DYNLRB1/DTL/SDE2/IMPACT/C9orf116/E2F4/PPP1CC/PPP1CA/EGFR/ATR/CLOCK/PRKAA1/FMR1/MDM2/SEMA5B/CHRNB2/DDB2/IFT20/GUCY2D/ERCC2/POLD1/RBL2/DCUN1D3/CUL4B/PPP1CB/GRK4/CABP4/MEN1/DBH/IL12B/PER3/GPR52/EIF2AK4/GPX1/MTOR/TRIAP1/BRSK1/APP/BAK1/TULP1/ATP1A2/CCDC66/CACNA2D4/RGR/UBE2B/CTNS/PDC/GJA10/CACNA1F/COPS3/FEN1/NR2F6/GNA11/RP1/ZRANB3/OPN4/SYNPO/ERCC8	141
BP	GO:0010822	positive regulation of mitochondrion organization	58/7096	117/18670	0.006934	0.0458	0.03415	BMF/RAC2/PINK1/HPS4/PMAIP1/FBXW7/YWHAH/GSK3B/CSNK2A2/CDC37/MIEF1/FIS1/HIF1A/UBE2D3/DDHD1/HTRA2/SFN/TNFSF10/CASP8/ATG13/CHCHD10/PLAUR/PPARGC1A/RHOU/PDCD5/ARIH2/BCL2L11/VPS13D/MAPK8/ABLIM3/MMP9/BCL2/BAX/MICALL2/GZMB/MLLT11/UBL4B/YWHAQ/SREBF2/FZD5/DNM1L/HSPA1L/MUL1/PRKAA1/SH3GLB1/YWHAE/BAD/TREM2/PLA2G6/UBL5/PPP1R13B/BAP1/MOAP1/WDR35/YWHAG/OPTN/BAK1/MGARP	58
BP	GO:0010906	regulation of glucose metabolic process	58/7096	117/18670	0.006934	0.0458	0.03415	IGF1/PDK4/FBP1/PTPN2/PMAIP1/ADIPOR1/SIK1/SLC45A3/COX11/GSK3B/KAT2B/PDK2/DYRK2/IGFBP4/LEP/PPP1R3E/INSR/PPP1R3D/DDB1/SLC35B4/ACACB/SIRT1/DGAT2/IRS2/DUSP12/PPARGC1A/MLYCD/NLN/GNB3/LCMT1/SLC25A12/KHK/PFKFB1/INPP5K/PPP1R3B/PDK1/PPP1R3F/FOXK2/PFKFB2/ZMPSTE24/NFE2L1/SERPINA12/PPP1CA/MST1/PPARA/KAT2A/BAD/RORA/OGT/PPP1CB/ESRRB/MTOR/GCG/SESN2/C1QTNF3/WDR5/FAM3A/NKX1-1	58
BP	GO:0031398	positive regulation of protein ubiquitination	58/7096	117/18670	0.006934	0.0458	0.03415	NOD2/BCL10/PINK1/SMAD7/ARRDC4/BIRC2/FBXW7/RNF111/UBE2N/SKP2/DCUN1D1/TICAM1/NMI/UBE3A/ARRDC3/ARRB1/WFS1/UBE2S/RASSF5/PTTG1IP/TRAF6/PTPN22/HSPA5/CDK9/LRRK2/MYCBP2/HSPBP1/SPHK1/PHF23/DCUN1D5/AIMP2/BIRC3/ADRB2/DERL1/TSPYL5/TBC1D7/PEF1/KLHL40/UBE2C/BIRC7/STUB1/RNF20/FBXO4/COMMD1/BRCA1/FANCM/DCUN1D3/CDC20/MASTL/PIN1/DCUN1D4/TOPORS/MALT1/XIAP/PAXIP1/CHFR/AVPR2/MAPK9	58
BP	GO:0018279	protein N-linked glycosylation via asparagine	20/7096	33/18670	0.007004	0.04605	0.03433	MCFD2/MGAT2/DAD1/MGAT5/STT3A/OST4/UBE2J1/UBE2G2/DPM1/RPN2/STT3B/NUDT14/ASGR2/LMAN1/TUSC3/DPM3/ASGR1/VCP/DDOST/ALG8	20
BP	GO:0050718	positive regulation of interleukin-1 beta secretion	20/7096	33/18670	0.007004	0.04605	0.03433	NOD2/WNT5A/LILRA5/NLRP3/LILRA2/NLRP12/P2RX7/AIM2/TRIM16/PANX1/TLR4/HMGB1/CASP1/LGALS9/FZD5/TLR8/NLRP1/NLRP2/CCL19/HMGB4	20
BP	GO:0090305	nucleic acid phosphodiester bond hydrolysis	136/7096	302/18670	0.007019	0.04605	0.03433	RNASE2/PCF11/ZFP36/ENPP2/AIFM1/TDP2/RNASEH2B/AGO2/DIS3L/RPP38/MOV10/CSTF3/DNASE2B/ERCC4/SND1/RAD1/TSN/RNASE3/RNASE1/N4BP2/RPA1/ANGEL1/ISG20/ISG20L2/XRN2/HELZ2/ENDOD1/DDB1/PIWIL4/ASTE1/SETMAR/TOE1/KRI1/CASP3/NMNAT1/POLD4/LACTB2/APTX/DFFA/RNASE6/SAMHD1/DCP1B/DCP2/POLD2/ZC3H12D/HMGB1/RPP25/ELAC1/ABT1/USB1/MRPL44/DNASE1/SLFN13/IL6/CPSF3/RPP14/RFC3/RPS21/RNASEH1/GTF2H4/DICER1/DCPS/AEN/POLG/NHP2/LAS1L/FIP1L1/XRN1/REXO2/PCNA/BAX/EXOSC2/HMGB2/ERCC1/ZC3H12C/EDC4/AGO1/DDX1/RNASEL/UBC/GEN1/ST20/EXOSC7/RCL1/DCLRE1A/CNOT7/DNASE1L2/ERI3/FANCM/RPP40/DDB2/KPNA1/ANKLE1/ERCC2/EXO1/POLD1/DXO/TATDN1/DCLRE1C/DIS3L2/RAD9A/EXOSC9/EXOSC3/CUL4B/TDP1/RPPH1/POP7/CPSF2/REXO4/DROSHA/ANKRD31/APLF/ERN1/RBX1/EXOSC6/CPSF1/PNPT1/CPSF7/EXOSC8/KPNB1/NUDT16/ATAD5/ENDOG/POLR2I/PNKP/RRS1/DNASE2/FEN1/PGAP1/POLR3K/TATDN3/ZRANB3/ENDOV/HORMAD1/EXOSC5/MIR146A	136
BP	GO:0002313	mature B cell differentiation involved in immune response	13/7096	19/18670	0.007026	0.04605	0.03433	DLL1/NOTCH2/LFNG/DOCK10/PTK2B/PLCG2/ITM2A/LGALS1/ADA/ITFG2/DOCK11/CDH17/GPR183	13
BP	GO:0002726	positive regulation of T cell cytokine production	13/7096	19/18670	0.007026	0.04605	0.03433	NLRP3/IL18R1/TRAF6/RSAD2/IL1B/IL1R1/IL6/FZD5/IL18/TRAF2/TNFSF4/PRKCZ/MALT1	13
BP	GO:0034138	toll-like receptor 3 signaling pathway	13/7096	19/18670	0.007026	0.04605	0.03433	TNIP2/TNFAIP3/FLOT1/TICAM1/PTPN22/CASP8/WDFY1/FADD/HAVCR2/TLR3/UNC93B1/TIRAP/RFTN1	13
BP	GO:0045063	T-helper 1 cell differentiation	13/7096	19/18670	0.007026	0.04605	0.03433	ANXA1/STAT6/IL4R/IL18R1/SOCS5/SEMA4A/RELB/HMGB1/HLX/TNFSF4/CD80/MTOR/CCL19	13
BP	GO:0048199	vesicle targeting, to, from or within Golgi	39/7096	74/18670	0.007028	0.04605	0.03433	SERPINA1/F5/MCFD2/KLHL12/CTSC/SEC22B/CD59/ANKRD28/SAR1B/TRAPPC6A/CSNK1D/PPP6R1/CNIH3/TRAPPC5/CTSZ/ARFGAP3/TMED10/WIPI1/BET1/GOSR2/GOSR1/STX5/SAR1A/PPP6C/TRAPPC6B/TRAPPC9/NAPA/TBC1D20/COL7A1/LMAN1/PEF1/SEC23IP/TRAPPC2L/CEP19/TRAPPC3/SCFD1/PREB/SEC24A/SEC16B	39
BP	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling	61/7096	124/18670	0.007071	0.04624	0.03447	KLF4/IGF1/FYN/PTPN6/LYN/FLT1/PPARD/PRR5/JAK2/TNF/GAB1/PTPN13/HCLS1/UBE3A/IER3/HGF/LEP/INSR/PIK3IP1/NCF1/FLT3/PDGFC/EPOR/FGR/IGF1R/CAT/CCL5/RASGRP1/SEMA4D/SIRT1/PPP1R16B/IRS2/PDGFB/PPP2R5C/PTK2/CEP55/NEDD4/PIK3CD/OSM/UNC5B/PDGFA/BTN2A2/F2R/SERPINA12/EGFR/IL18/MAPK1/STAMBP/FBXL2/MAZ/FSHR/PPP2R5B/PIK3CG/RELN/PIP5K1B/LIME1/NLRC3/ERBB3/PDGFD/NTRK2/PIK3CB	61
BP	GO:0019218	regulation of steroid metabolic process	61/7096	124/18670	0.007071	0.04624	0.03447	VDR/ASAH1/POR/STARD4/SOD1/ATP1A1/NFYC/GPAM/DDX20/PANK2/APOC1/SQLE/EGR1/TNF/AKR1C3/NFKB1/RAN/IGFBP7/APOE/HMGCR/HMGCS1/SCD/LEP/ERLIN1/BMP2/IL1B/LAMTOR1/LDLR/LMF1/ERLIN2/FDPS/ACACB/SIRT1/DGAT2/PPARGC1A/FGF1/ARV1/GNB3/TM7SF2/APOA5/IDI1/BMP5/SCAP/ABCG1/SC5D/SREBF2/ACADVL/STUB1/SERPINA12/INSIG1/PRKAA1/APOA1/CYP27B1/RORA/SNAI1/IFNG/MBTPS2/ELOVL6/MBTPS1/KPNB1/NR1H4	61
BP	GO:0016125	sterol metabolic process	79/7096	166/18670	0.007154	0.04671	0.03482	POR/CYP27A1/SOD1/NFYC/GPAM/NPC2/PPARD/LIPA/CYB5R1/FAXDC2/APOC1/SCARB1/SQLE/SOAT1/CETP/RAN/APOE/HMGCR/LIMA1/HDLBP/CLN8/OSBPL1A/HMGCS1/CYP1B1/SCD/LEP/ERLIN1/CNBP/CEBPA/CAT/ACLY/ABCA1/LDLR/LMF1/ERLIN2/FDPS/ACACB/APOBR/DGAT2/G6PD/FGF1/ARV1/APOL1/GNB3/TM7SF2/APOA5/MSMO1/IDI1/PRKAG2/LCAT/RXRA/SCAP/CYP26B1/ABCG1/APOL2/SC5D/CH25H/EBPL/CLN6/SREBF2/ACADVL/CYB5R3/FDX1/NFE2L1/SERPINA12/INSIG1/ACAA2/PRKAA1/APOA1/SMPD1/CYP26A1/MBTPS2/APP/ELOVL6/MBTPS1/KPNB1/CYP46A1/NR1H4/SNX17	79
BP	GO:0090181	regulation of cholesterol metabolic process	34/7096	63/18670	0.007158	0.04671	0.03482	POR/SOD1/NFYC/GPAM/SQLE/RAN/APOE/HMGCR/HMGCS1/SCD/ERLIN1/LDLR/LMF1/ERLIN2/FDPS/ACACB/DGAT2/FGF1/ARV1/GNB3/TM7SF2/IDI1/SCAP/ABCG1/SC5D/SREBF2/ACADVL/SERPINA12/PRKAA1/MBTPS2/ELOVL6/MBTPS1/KPNB1/NR1H4	34
BP	GO:0071539	protein localization to centrosome	19/7096	31/18670	0.007194	0.04685	0.03493	NUP62/SNX10/GSK3B/GOLGB1/PCM1/CSNK1D/CEP131/UBXN2B/KIAA0753/NSFL1C/SPAG5/BICD1/BBS4/DISC1/HOOK3/DCTN2/CEP83/AURKA/C2CD3	19
BP	GO:2000406	positive regulation of T cell migration	19/7096	31/18670	0.007194	0.04685	0.03493	CCR2/OXSR1/WNT5A/TNFRSF14/ADAM8/CXCL10/CXCL12/DOCK8/CXCL13/ITGA4/AIF1/CCL5/CD99L2/TMEM102/FADD/ADAM17/CCL20/RHOA/APP	19
BP	GO:0039531	regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway	14/7096	21/18670	0.007306	0.04739	0.03533	BIRC2/DDX60/PUM2/NPLOC4/SEC14L1/ANKRD17/BIRC3/C1QBP/GPATCH3/RIOK3/TRIM15/NLRX1/TSPAN6/ZCCHC3	14
BP	GO:0043153	entrainment of circadian clock by photoperiod	14/7096	21/18670	0.007306	0.04739	0.03533	BHLHE40/SIK1/PER2/RBM4/RBM4B/PML/FBXL3/CRTC1/ID2/PPP1CC/PPP1CA/PPP1CB/PER3/NR2F6	14
BP	GO:1904469	positive regulation of tumor necrosis factor secretion	14/7096	21/18670	0.007306	0.04739	0.03533	WNT5A/LILRA5/LILRA2/FRMD8/DDX58/DHX9/MAVS/LRRK2/IFIH1/LGALS9/FZD5/IFNGR1/HAVCR2/IFNG	14
BP	GO:2000114	regulation of establishment of cell polarity	14/7096	21/18670	0.007306	0.04739	0.03533	RAP1B/RNF41/DOCK8/PTK2B/ARFGEF1/CDH5/FLOT2/KRIT1/WDPCP/BCAS3/KIF20B/KANK1/RUFY3/ROCK2	14
BP	GO:0021799	cerebral cortex radially oriented cell migration	18/7096	29/18670	0.007349	0.04752	0.03543	SUN2/MBOAT7/FBXO45/CDK5/PAFAH1B1/SRGAP2C/P2RY12/DIXDC1/SYNE2/SRGAP2/DISC1/NDEL1/DAB1/CDK5R2/NR2E1/RELN/RTN4/LHX6	18
BP	GO:0072606	interleukin-8 secretion	18/7096	29/18670	0.007349	0.04752	0.03543	TLR1/TLR2/ANXA1/WNT5A/CD58/FCN1/CD2/FFAR2/LEP/MAPKBP1/HYAL2/PTPN22/CHI3L1/LGALS9/F2R/C5AR2/CD244/TLR6	18
BP	GO:1902624	positive regulation of neutrophil migration	18/7096	29/18670	0.007349	0.04752	0.03543	RAC2/CAMK1D/ADAM8/CD74/CD99/IL1R1/RAC1/C3AR1/MOSPD2/CD99L2/C1QBP/CXCR2/LBP/DAPK2/CCL19/TIRAP/CCR7/IL23A	18
BP	GO:0006541	glutamine metabolic process	15/7096	23/18670	0.007453	0.04777	0.03562	SIRT4/GMPS/CTPS2/ASNSD1/GLUD1/ALDH5A1/ASNS/PPAT/GLS/GFPT1/CTPS1/CAD/GFPT2/PHGDH/NR1H4	15
BP	GO:0009595	detection of biotic stimulus	15/7096	23/18670	0.007453	0.04777	0.03562	NOD2/TLR1/TLR2/CLEC7A/NLRP3/LY96/SCARB1/TLR4/CD1D/PGLYRP4/CRTAM/TREM2/LBP/SMO/TLR6	15
BP	GO:0010499	proteasomal ubiquitin-independent protein catabolic process	15/7096	23/18670	0.007453	0.04777	0.03562	PSMB9/ENC1/KEAP1/PSMB8/PSMA5/PSMB10/PSMA1/PSMA4/PSMB1/PSMB3/PSMB5/NFE2L2/PSMA2/PSMB2/PSMB4	15
BP	GO:0032373	positive regulation of sterol transport	15/7096	23/18670	0.007453	0.04777	0.03562	NFKBIA/SCP2/APOE/NR1H2/ABCA1/LRP1/SIRT1/ABCG1/NR1H3/ABCB4/ABCA7/ANXA2P2/APOA1/ANXA2/PTCH1	15
BP	GO:0032376	positive regulation of cholesterol transport	15/7096	23/18670	0.007453	0.04777	0.03562	NFKBIA/SCP2/APOE/NR1H2/ABCA1/LRP1/SIRT1/ABCG1/NR1H3/ABCB4/ABCA7/ANXA2P2/APOA1/ANXA2/PTCH1	15
BP	GO:0045821	positive regulation of glycolytic process	15/7096	23/18670	0.007453	0.04777	0.03562	IGF1/PFKFB3/P2RX7/HIF1A/INSR/PFKFB4/PFKFB1/PFKFB2/ARNT/PRKAA1/PSEN1/IFNG/ESRRB/ZBTB20/APP	15
BP	GO:0009649	entrainment of circadian clock	17/7096	27/18670	0.007454	0.04777	0.03562	ARNTL2/BHLHE40/SIK1/PER2/GNAQ/RBM4/RBM4B/PML/FBXL3/CRTC1/ID2/PPP1CC/PPP1CA/PPP1CB/PER3/NR2F6/GNA11	17
BP	GO:0036475	neuron death in response to oxidative stress	17/7096	27/18670	0.007454	0.04777	0.03562	ATG7/PINK1/TSC1/FBXW7/SLC7A11/ATF4/HIF1A/MCL1/TLR4/NCOA7/FZD1/WNT1/NR4A3/LANCL1/ENDOG/TLR6/OXR1	17
BP	GO:2000144	positive regulation of DNA-templated transcription, initiation	17/7096	27/18670	0.007454	0.04777	0.03562	SRF/PSMC4/MITF/SUB1/CREB1/SETX/PSMC3/CAND1/PSMC6/HNF1B/BCLAF1/FOSL1/HNF1A/PSMC5/PSMC2/PAXIP1/WNT10B	17
BP	GO:2000482	regulation of interleukin-8 secretion	16/7096	25/18670	0.007495	0.04797	0.03576	TLR1/TLR2/ANXA1/WNT5A/CD58/FCN1/CD2/FFAR2/MAPKBP1/HYAL2/PTPN22/LGALS9/F2R/C5AR2/CD244/TLR6	16
BP	GO:0090114	COPII-coated vesicle budding	38/7096	72/18670	0.007507	0.04797	0.03576	SERPINA1/F5/MCFD2/KLHL12/CTSC/SEC22B/CD59/ANKRD28/SAR1B/TRAPPC6A/CSNK1D/PPP6R1/CNIH3/TRAPPC5/CTSZ/TMED10/BET1/VAPB/GOSR2/STX5/SAR1A/PPP6C/TRAPPC6B/TRAPPC9/NAPA/TBC1D20/COL7A1/LMAN1/PEF1/INSIG1/SEC23IP/TRAPPC2L/TRAPPC3/SCFD1/PREB/SEC24A/SEC31B/SEC16B	38
BP	GO:1903747	regulation of establishment of protein localization to mitochondrion	38/7096	72/18670	0.007507	0.04797	0.03576	RAC2/PINK1/HPS4/PMAIP1/SIRT4/FBXW7/YWHAH/CSNK2A2/UBE2D3/HTRA2/SFN/CASP8/ATG13/LRRK2/RHOU/PDCD5/ARIH2/MAPK8/ABLIM3/BCL2/MICALL2/GZMB/UBL4B/LMAN1/YWHAQ/SREBF2/FZD5/HSPA1L/PRKAA1/PARL/SH3GLB1/YWHAE/BAD/UBL5/PPP1R13B/BAP1/DNAJA1/YWHAG	38
BP	GO:0010952	positive regulation of peptidase activity	92/7096	197/18670	0.007549	0.04819	0.03593	S100A9/S100A8/FN1/FYN/MAPK12/CLEC7A/GRN/BCL10/LYN/PINK1/AIFM1/GRAMD4/STAT3/CTSD/NLRP3/TNFRSF10A/PMAIP1/MBP/DDRGK1/LGMN/MYC/NLRP12/JAK2/FAS/BCAP31/TNF/IFT57/PRELID1/PSME1/AIM2/CLPX/FIS1/ARRB1/TFAP4/HTRA2/CYFIP2/TNFSF10/CASP8/AGER/ADRM1/DAPK1/PML/CASP5/HMGB1/TRADD/PPM1F/SIRT1/TTBK1/LCK/CR1/EGLN3/PDCD5/DDX3X/PRR7/BCL2L11/P2RX1/PSME3/MEFV/BAX/CRADD/CASP1/KHDC1/LGALS9/ST20/MAP3K5/F2R/TNFRSF10B/MUL1/FADD/TRAF2/CASP4/COL4A3/BAD/DAP/NLRP1/ST18/NLRP2/WDR35/DIABLO/F3/VCP/RHOA/APP/SNCA/MALT1/BAK1/PICALM/ROCK2/AKIRIN2/MIR205/EFNA3/SOX7	92
BP	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	60/7096	122/18670	0.007564	0.04824	0.03596	CBFA2T3/SMAD7/KEAP1/DDRGK1/BCAP31/HFE/RAD23B/FHIT/RYBP/GSK3B/RNF19B/UBE2K/SGTA/ZFAND2A/SOCS5/CSNK1D/RNF217/CEBPA/PLK2/ANKIB1/GCLC/SDCBP/ARAF/CLU/UCHL5/LRRK2/SUMO1/GLMN/HSPBP1/CSNK1A1/CSNK1E/ARIH2/PLK3/UBQLN2/TRIB2/BBS7/DET1/NKD2/KLHL40/STUB1/NFE2L2/COMMD1/USP7/DVL1/MAP1A/PSEN1/MDM2/UBXN1/OGT/HSP90AB1/CLEC16A/FOXF2/VCP/AURKA/RBX1/BAG5/SMARCC1/CHFR/WNT10B/MAPK9	60
BP	GO:0045123	cellular extravasation	33/7096	61/18670	0.007623	0.04846	0.03613	CCR2/CX3CR1/PTGER4/IL27RA/SELL/BST1/AZU1/ITGB7/ADAM8/TNF/CXCL12/PTAFR/LEP/ITGA4/CD99/ABR/AGER/CRK/IL1R1/GCNT1/BCR/SELPLG/CD99L2/PIK3CD/CD47/MADCAM1/FER/PLCB1/FADD/PIK3CG/PRTN3/CX3CL1/PDGFD	33
BP	GO:0045604	regulation of epidermal cell differentiation	33/7096	61/18670	0.007623	0.04846	0.03613	VDR/DLL1/ZFP36/KEAP1/CBFB/CTSK/EZH2/TRIM16/NCOA3/SFN/PTCH2/SFRP4/KRT36/KLF7/ALOX15B/MAFG/BMP4/SRSF6/CTSV/HES1/CDSN/AQP3/HEY2/CYP27B1/REG3G/KRT84/ROCK2/HOXA7/PTCH1/GRHL2/MYCL/GRHL1/CD109	33
BP	GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	33/7096	61/18670	0.007623	0.04846	0.03613	NFKBIZ/ANXA1/CD55/ARG2/BCL6/NLRP3/SH3RF1/SMAD7/IL4R/CBFB/SOCS5/ZBTB7B/NFKBID/AGER/HMGB1/IL12RB1/CD274/LGALS9/HLX/IL18/TNFSF4/SOCS1/IFNG/IL12B/PRKCZ/CD80/TBX21/PRKCQ/CD83/CCL19/MALT1/TWSG1/IL23A	33
BP	GO:0031145	anaphase-promoting complex-dependent catabolic process	42/7096	81/18670	0.007636	0.04846	0.03613	PSMB9/PSMB8/PSMA5/PSMD11/PSME1/UBE2S/PSMB10/PSMA1/PSMA4/PSMB1/PSMC4/UBE2E1/PSMD13/PSMB3/CDC23/PSMB5/PSMD6/ANAPC5/BUB3/PSMC3/PSME3/PSMC6/ANAPC7/UBC/UBE2C/CDC26/PSMC1/ANAPC4/PSMD8/PSMA2/CDC27/CDC20/PSMC5/PSMC2/PSMB2/PSMD4/AURKA/ANAPC11/PSMD1/PSMB4/PSMD9/PSMD3	42
BP	GO:1903533	regulation of protein targeting	42/7096	81/18670	0.007636	0.04846	0.03613	ITGAM/FYN/RAC2/PINK1/CHP1/HPS4/SIRT4/CIB1/FBXW7/C2CD5/CSNK2A2/MIEF1/FIS1/PAK1/UBE2D3/HTRA2/CDK5/HRAS/GDI1/ATG13/LRRK2/MYO1C/RHOU/PDCD5/ARIH2/ABLIM3/INPP5K/MICALL2/UBL4B/LMAN1/SREBF2/FZD5/DMTN/HSPA1L/CEMIP/PRKAA1/PARL/SH3GLB1/UBL5/BAP1/CACNB3/ITGB1BP1	42
BP	GO:0071229	cellular response to acid chemical	97/7096	209/18670	0.007697	0.0488	0.03638	KLF4/KLF2/FYN/KCNMB1/PTGER4/PDK4/LYN/PINK1/GCLM/WNT5A/PTGER2/CAPN2/ADNP2/GNB1/FOLR2/CEBPB/EGR1/TNF/AKR1C3/TESC/PKD2/SH3BP4/CDK4/TWF2/PTAFR/FFAR2/PTK2B/LEP/BCL11A/P2RY6/BAIAP2/HTRA2/PDGFC/AKR1C1/VEGFA/KLHL22/GCLC/ABCA1/LAMTOR1/XRCC5/PTK6/LDLR/RRAGD/CREB1/DGAT2/PDGFB/GNG2/PPARGC1A/ATM/SETX/SHMT2/HDAC2/AKAP8/MYOG/LAMTOR4/CYP26B1/NME1/CPEB1/CPT1A/ABCB4/CYBA/CYBB/HNRNPD/CPEB3/TEAD2/RRAGA/UCP1/LAMTOR5/NSMF/SHMT1/EGFR/AMIGO1/ABL2/SESN1/DNMT3A/FZD4/TNFSF4/PRKAA1/HAMP/PID1/P2RY4/UBR1/SOCS1/ATP7A/RET/FZD7/MMP2/MTOR/WNT6/WNT10B/LANCL2/NR1H4/SESN2/SLC38A9/PDGFD/FZD10/NTRK2	97
BP	GO:0044764	multi-organism cellular process	27/7096	48/18670	0.007728	0.0489	0.03645	IRF7/BIRC2/SLC22A5/DDX60/HYAL2/DDX58/FCHSD1/CCR5/LSM14A/PUM2/NPLOC4/IFIH1/SEC14L1/ANKRD17/BIRC3/PGLYRP4/C1QBP/GPATCH3/RIOK3/REG3G/HRG/TRIM15/CD4/NLRX1/TSPAN6/ZCCHC3/FCHSD2	27
BP	GO:0072604	interleukin-6 secretion	27/7096	48/18670	0.007728	0.0489	0.03645	IL27RA/SYT11/LILRA5/BANK1/MBP/LILRA2/TNF/IL1RAP/LEP/HYAL2/DDX58/PTPN22/IL1B/AIF1/DHX9/HMGB1/MAVS/CD200R1/IFIH1/LGALS9/RABGEF1/F2R/TLR8/TRPV4/C5AR2/C1QTNF3/IL17RC	27
BP	GO:0070085	glycosylation	122/7096	269/18670	0.00783	0.0495	0.0369	TMTC3/PGM3/EXTL2/MCFD2/MGAT2/DAD1/B3GNT8/VEGFB/CHP1/MGAT5/MAN1C1/POMGNT2/LFNG/GALNT14/PIGV/IL15/FUT4/EXT2/EXT1/FUT7/TET2/MGAT4B/B3GNT2/MAN2A2/STT3A/NAGPA/B4GALT6/ARFGEF1/POGLUT1/ALG2/KRTCAP2/B3GNT5/TRAK2/OST4/PMM2/ST6GALNAC4/UBE2J1/ST3GAL2/GALNT7/LMF1/MUC2/B3GALT6/FKRP/ALG6/UBE2G2/SDF2L1/DPY19L4/PIGB/DPM1/GALNT6/TMTC2/SERP1/GCNT1/RPN2/GALNT12/DOLK/MUC1/GALNT10/STT3B/NUDT14/ALG12/ALG10/B4GALNT1/MGAT3/MAN1B1/ASGR2/LMAN1/DOLPP1/FUT6/B4GALT5/CLN5/COG6/ST8SIA4/MGAT5B/ALG13/MAN1A2/MOGS/POMT1/TUSC3/TMEM258/SLC35C1/NUS1/DHDDS/GALNT9/SRD5A3/ST6GALNAC5/XXYLT1/GFPT1/POMT2/PSEN1/DPM3/B3GNT4/GGTA1P/ST3GAL1/DPY19L2/MUC6/OGT/TRAK1/GCNT2/ST6GALNAC3/B3GAT3/MUCL1/ST6GALNAC6/COG7/ASGR1/VCP/C1GALT1/B3GALT5/GFPT2/B4GALT1/GALNT1/ALG14/EDEM3/ST8SIA1/DDOST/ST3GAL5/DPAGT1/DPY19L2P2/ALG8/TET1/ALG3/GALNT15	122
BP	GO:0050769	positive regulation of neurogenesis	206/7096	474/18670	0.007895	0.04985	0.03717	S100A9/CCR2/FN1/FYN/TRIM32/CX3CR1/TLR2/DPYSL3/SKIL/GRN/LYN/WNT5A/CYB5D2/TIMP2/BCL6/RAB11A/FLNA/MMD/CAMK1D/MAP2K1/RGS2/ALK/DVL2/TNF/EZH2/EPHB2/ARHGDIA/GPRC5B/APOE/ZEB2/ACTR2/PLAA/CXCL12/MIR142/PLXNB2/RELA/LRP8/TWF2/TGFB1/SIN3A/ARSB/HGF/HIF1A/PAK1/RAPGEF2/MEGF8/SS18L2/PTK2B/PLXNC1/CSNK1D/SRF/SCN1B/BAIAP2/ITSN1/TCF12/BMP2/HSPA5/NCK1/FIG4/VEGFA/TNFRSF12A/PAFAH1B1/SRGAP2C/IL1B/GDI1/GRIP1/CREB3L2/FBXO38/XRCC5/NUMB/PTK6/ARHGEF2/RAP1A/SEMA4D/P2RY12/ANKRD27/LRP1/IL6ST/NPTN/BMP7/TMEM106B/CAPRIN1/ZNF488/TTBK1/ETV5/IL6/KALRN/ELL3/CYFIP1/ZNF609/ASPM/CRTC1/PLAG1/ARF1/CSNK1E/SETX/DICER1/GDPD5/PLXNA1/HDAC2/BMP5/NRP1/DISC1/PLXND1/BCL2/BMP4/AVIL/L1CAM/RGS14/ID2/MARK2/KCTD11/CLCF1/NME1/KIF20B/LPAR3/IST1/SPINT1/NDEL1/DAB1/MOB2/SHANK1/CPEB3/LIG4/SEMA5A/PRMT5/ITGA3/TGIF2/LPAR1/HES1/BHLHB9/DNM1L/AP2A1/FZD1/NFE2L2/IMPACT/NSMF/CNTF/PPP1CC/MUL1/DCT/AMIGO1/ABL2/SS18L1/FZD4/ITSN2/SLIT2/LRRC7/DVL1/CPNE1/PSEN1/FMR1/GPC2/SHOX2/EIF4G1/KATNB1/TREM2/RASAL1/MAP3K13/RUFY3/IFNG/NUMBL/PLXNA3/SYT1/RET/TRAK1/CPNE9/TMEM30A/IL1RAPL1/PPP2R5B/DUOXA1/PLXNA2/SYT2/PRPF19/SYT4/RELN/MTOR/CHODL/RHOA/HMG20B/DAG1/C21orf91/CX3CL1/PARP6/PTPRZ1/CRABP2/FAIM/RIMS2/SRRT/OTP/SOCS2/SMO/SHANK3/BIN1/MMD2/MACF1/CNTN1/TRPV2/ZMYND8/NTRK2/MEF2C/CAMK2B/BMPR2/MIR146A/GDF5/ZNF335	206
BP	GO:0043200	response to amino acid	56/7096	113/18670	0.007939	0.05009	0.03734	FYN/LYN/GCLM/AIFM1/TMBIM6/CAPN2/CEBPB/GSTP1/TNF/RELA/SH3BP4/ALAD/BCL11A/BAIAP2/PDGFC/CASP3/KLHL22/GCLC/LAMTOR1/RRAGD/CREB1/PPARGC1A/CRLS1/LAMTOR4/PCNA/ASNS/CDKN1B/CPEB1/CFL1/GSS/PDX1/CYBA/CYBB/HNRNPD/CPEB3/RRAGA/TOMM20/LAMTOR5/NSMF/EGFR/AMIGO1/SESN1/DNMT3A/UBR1/SOCS1/BAD/ATP7A/GPRC6A/MMP2/MTOR/RHOA/CHUK/SESN2/SLC38A9/PDGFD/NTRK2	56
BP	GO:0060996	dendritic spine development	49/7096	97/18670	0.007978	0.05023	0.03745	SIPA1L1/ARF6/DNM3/DOCK10/EPHB2/APOE/ACTR2/LRP8/UBE3A/ARF4/BAIAP2/ITSN1/ACSL4/CDK5/PLK2/PAFAH1B1/SRGAP2C/PAK2/ARID1B/CAPRIN1/KALRN/LRRK2/ARC/ARF1/SRGAP2/PDLIM5/HDAC2/DISC1/CFL1/SHANK1/CPEB3/LPAR1/CAMK2A/FSTL4/BHLHB9/DNM1L/DVL1/PSEN1/FMR1/EPHB1/RELN/MTOR/C21orf91/ASAP1/WNT7A/SHANK3/ZMYND8/MEF2C/CAMK2B	49
BP	GO:2001022	positive regulation of response to DNA damage stimulus	49/7096	97/18670	0.007978	0.05023	0.03745	SKIL/MAD2L2/PARP9/EID3/PMAIP1/EYA3/CEBPG/MYC/UBE2N/SPIRE1/ERCC6/ACTR2/EEF1E1/PRKCD/UIMC1/TMEM161A/SETMAR/DHX9/HMGB1/SMCHD1/SIRT1/ATM/DTX3L/HDAC10/NACC2/PCNA/XRCC1/PARP3/FUS/TIMELESS/KDM4D/SPRED1/BRCA1/EGFR/ATR/FMR1/EYA4/ANKLE1/BCLAF1/RAD9A/MSX1/BRCC3/MGMT/WAS/PAXIP1/NUDT16/SPIDR/HIC1/ERCC8	49
BP	GO:0051100	negative regulation of binding	80/7096	169/18670	0.008056	0.05068	0.03778	STMN1/MAD2L2/C9orf72/TMBIM6/MEPCE/FBXW7/PER2/JAK2/HFE/ZNF304/NFKBIA/HMOX1/ERCC4/GSK3B/TMC8/ACTB/SIN3A/GTPBP4/ENHO/LRPAP1/PRKCD/ADAM15/RUVBL2/ITGA4/TFAP4/HABP4/HSPA5/BTAF1/SP100/CTSZ/IFIT2/DTNBP1/GZMA/ZNF593/SYMPK/HEY1/EIF2S1/GPSM1/TTBK1/PDGFB/LRRK2/TDG/SUMO1/SRI/CSNK1E/HDAC2/CYP2D6/MAPK8/DISC1/BAX/ID2/ADRB2/ZFP90/RSF1/PEX19/GTF2F1/IFIT1/STUB1/PPP1CA/PEX14/PPARA/BAG2/HEY2/DVL1/CPNE1/PSEN1/EFHB/GNL3L/PIN1/CARM1/MSX1/AURKA/PIM2/ITGB1BP1/TTBK2/MET/SLN/CFHR5/SMO/P2RY1	80
BP	GO:1901888	regulation of cell junction assembly	45/7096	88/18670	0.008137	0.05114	0.03812	S100A10/TSC1/RAP1B/FLOT1/CBFB/LDB1/TNF/SLC9A1/DUSP3/PEAK1/RAPGEF2/VEGFA/ABL1/RAP1A/LRP1/GPBAR1/PPM1F/SLK/RAC1/MYO1C/PTK2/ARHGAP6/LIMCH1/NPHP4/NRP1/WDPCP/BCAS3/PRKACA/FZD5/MMP14/DMTN/CORO1C/CLASP2/RCC2/SNAI1/HRG/MAP4K4/RHOA/LIMS1/ITGB1BP1/ROCK2/GJA1/MACF1/PTPRJ/FMN1	45
BP	GO:0071260	cellular response to mechanical stimulus	41/7096	79/18670	0.008167	0.05123	0.03819	MYD88/PTGER4/BCL10/IRF1/ATP1A1/PTGS2/TNFRSF10A/CD40/FAS/SLC9A1/NFKB1/TGFB1/TLR5/TLR4/HABP4/GCLC/CASP8/IL1B/CASP5/RAC1/CNN2/MAPK8/CRADD/HDAC4/CASP2/CASP1/ITGA2/CYBA/TNFRSF10B/EGFR/FADD/TLR8/MAP2K4/BAD/MAP3K1/TLR3/DAG1/ENG/BAK1/ATP1A2/GJA1	41
BP	GO:1900034	regulation of cellular response to heat	41/7096	79/18670	0.008167	0.05123	0.03819	IER5/NUP62/NUP160/NUP214/GSK3B/DNAJB1/NUP85/SEH1L/RPA1/NUP43/DNAJC2/POM121/SIRT1/MLST8/DNAJB6/PTGES3/ATM/DNAJC7/HSBP1/MAPKAPK2/NUP88/NUP107/AKT1S1/CAMK2A/HSPA1L/CAMK2D/NUP93/ATR/BAG2/CHORDC1/NUP205/MAPK1/YWHAE/NUP50/CD34/HSP90AB1/MTOR/BAG5/POM121C/AAAS/CAMK2B	41
BP	GO:0071426	ribonucleoprotein complex export from nucleus	62/7096	127/18670	0.008194	0.05135	0.03828	TSC1/NXF1/SRSF5/NUP62/NUP160/CHTOP/NUP214/ENY2/AGFG1/RAN/ALYREF/RNPS1/EIF6/MAGOHB/SARNP/NUP85/NXT1/SEH1L/YTHDC1/NUP43/NPM1/HNRNPA2B1/RBM8A/FYTTD1/DDX19B/U2AF1/POM121/ZNF593/SRSF3/SYMPK/XPOT/CPSF3/FIP1L1/NUP88/THOC2/SRSF6/SRSF7/NUP107/CDC40/THOC5/POLR2D/U2AF1L4/EIF5A/NUP93/LTV1/THOC6/RIOK2/SSB/SRRM1/NUP205/SRSF4/EIF4E/NUP50/DHX38/MCM3AP/PCID2/CPSF2/CPSF1/RRS1/POM121C/AAAS/UPF1	62
BP	GO:0010977	negative regulation of neuron projection development	74/7096	155/18670	0.008213	0.05141	0.03833	RTN4R/DPYSL3/ARF6/DNM3/WNT5A/DENND5A/TSC1/SEMA4B/VIM/LRIG2/SPP1/CIB1/ULK2/YWHAH/CERS2/EPHB2/ARHGDIA/IFRD1/APOE/GSK3B/PTPRO/UBE3A/DGUOK/RAPGEF2/BCL11A/SEMA4A/CDK5/PLK2/TRAK2/PAFAH1B1/CTSZ/SRGAP2C/GDI1/SEMA4C/PAQR3/SEMA4D/LRP1/RAB29/LRRK2/DCC/PTK2/SEMA6B/HDAC2/NRP1/SEMA3B/KANK1/LGALS1/SYNGAP1/DAB1/INPP5F/RTN4RL1/SEMA5A/LPAR1/FSTL4/SLIT2/PSEN1/MDM2/SEMA5B/RTN4RL2/RUFY3/PLXNA3/SPOCK1/NR2F1/CARM1/MAP4K4/RHOA/TRPV4/RTN4/BAG5/KREMEN1/ASAP1/FGF13/LRP4/TRIM46	74
BP	GO:0010038	response to metal ion	161/7096	364/18670	0.008232	0.05144	0.03835	CRIP1/CRHBP/NQO1/S100A8/JUNB/SLC40A1/FOS/KCNMB1/DUSP1/ALOX5AP/MEF2A/FBP1/PPP2CA/FABP4/TXNIP/AQP9/FOSB/WNT5A/SOD1/MCOLN1/SYT11/JUND/RASGRP2/PTGS2/CUTA/LGMN/P2RX7/HFE/HMOX1/AKR1C3/PKD2/ATF4/CDK4/CYBRD1/KCNIP2/ALAD/ZNF658/HIF1A/NUDT1/MAP1LC3A/PTK2B/CPNE8/ARL13B/CYB5A/TCIRG1/NCF1/LOXL2/EIF2B5/RYR1/ALG2/CEBPA/HSPA5/CAT/CASP3/GCLC/CASP8/CPOX/GDI1/QDPR/CREB1/IGFBP2/ACO1/ATP7B/CCND1/TRPM2/SLC39A13/HOMER1/NDRG1/EIF2S1/ADCY7/MTF1/LRRK2/G6PD/PPARGC1A/S100A13/SYT6/CLIC4/SUMO1/HAAO/ADCY1/SPARC/XRCC4/SLC25A12/HVCN1/PAM/MYOG/CYP1A2/MAPK8/KHK/MMP9/BCL2/PCNA/NEDD4/ERCC1/FUS/ID2/CDKN1B/IL1A/GSS/PDX1/PEF1/CYBB/HNRNPD/LIG4/SORD/DMTN/CALR/SLC41A1/CACYBP/NFE2L2/NFE2L1/CAMK2D/PPP1CA/AHCYL1/EGFR/TPH2/SLC25A13/SYT13/DNMT3A/AQP3/MAOB/ADAM9/GIPR/CPNE1/PRKAA1/HAMP/MDM2/MAPK1/BAD/SYT9/RASAL1/CAPN3/CASQ2/ATP7A/SLC30A2/CHP2/CPNE3/SLC25A24/SYT1/CPNE9/SUCNR1/SYT2/TERT/SYT4/SYT5/KCNMA1/KRT14/CPNE2/APP/SNCA/KCNMB4/SLC30A10/CHUK/ENDOG/FGF23/ACTA1/CACNA1H/DAXX/ZACN/MEF2C/MAPK9	161
BP	GO:0007272	ensheathment of neurons	65/7096	134/18670	0.008252	0.05144	0.03835	TYMP/TLR2/HEXB/MPP5/SKI/ZSCAN26/TSC1/SOD1/CMTM8/PPARD/MBP/RNF10/CTSC/PSAP/TNFRSF21/TGFB1/HGF/GALC/MYO5A/NRG1/B4GALT6/EIF2B5/ZNF24/FIG4/FAM126A/NAB1/ZPR1/ATRN/S100B/MARVELD1/CLU/AFG3L2/NDRG1/ZNF488/EGR2/CST7/DICER1/SLC25A12/ADAM22/SH3TC2/MTMR2/LGI4/B4GALT5/LPAR1/PRX/MALL/AMIGO1/JAM3/ACER3/ERCC2/GNPAT/SCN8A/MTOR/SBF2/DAG1/ABCD1/TSPAN2/PTPRZ1/SLC8A3/EIF2B2/PLP1/KEL/KIF14/NTRK2/POU3F1	65
BP	GO:0008366	axon ensheathment	65/7096	134/18670	0.008252	0.05144	0.03835	TYMP/TLR2/HEXB/MPP5/SKI/ZSCAN26/TSC1/SOD1/CMTM8/PPARD/MBP/RNF10/CTSC/PSAP/TNFRSF21/TGFB1/HGF/GALC/MYO5A/NRG1/B4GALT6/EIF2B5/ZNF24/FIG4/FAM126A/NAB1/ZPR1/ATRN/S100B/MARVELD1/CLU/AFG3L2/NDRG1/ZNF488/EGR2/CST7/DICER1/SLC25A12/ADAM22/SH3TC2/MTMR2/LGI4/B4GALT5/LPAR1/PRX/MALL/AMIGO1/JAM3/ACER3/ERCC2/GNPAT/SCN8A/MTOR/SBF2/DAG1/ABCD1/TSPAN2/PTPRZ1/SLC8A3/EIF2B2/PLP1/KEL/KIF14/NTRK2/POU3F1	65
BP	GO:0046683	response to organophosphorus	65/7096	134/18670	0.008252	0.05144	0.03835	CRHBP/SLC8A1/JUNB/FOS/EZR/DUSP1/LDHA/AQP9/FOSB/SOD1/SRD5A1/RAP1B/JUND/PTGS2/BIRC2/STAT1/P2RX7/PKD2/RELA/TRIM16/PTAFR/RAPGEF2/PTK2B/PANX1/P2RY6/HSPA5/AKR1C1/IL1B/RAP1A/AHR/P2RY12/THBD/TRPM4/RFC3/SPARC/CRLS1/HCN4/P2RX1/PFKFB1/INPP5K/NME1/KCNQ1/TYMS/LPAR1/DMTN/FDX1/HSP90B1/P2RY4/FOSL1/PIK3CG/REN/CARM1/APP/P2RX2/CIB2/SSH1/PNPT1/HCN1/SLC8A3/WNT10B/ALDH3A1/MMP19/WT1/P2RY1/P2RX5	65
BP	GO:0002792	negative regulation of peptide secretion	71/7096	148/18670	0.008257	0.05144	0.03835	CRHBP/FN1/EZR/PTGER4/IL27RA/ANXA1/IL1R2/RHBDF2/GBP1/ARG2/SYT11/ERP29/TMBIM6/DPH3/LILRA5/NLRP3/HADH/TNFAIP3/BANK1/SIRT4/LGR4/ENY2/NLRP12/RGCC/FAM3D/TNF/CD74/TNFRSF21/APOE/HMGCR/LILRB1/CD22/PIM3/ENHO/LEP/SERPINB1/MAPKBP1/PTPN22/RSAD2/IL1B/PML/KALRN/CD200R1/KLF7/IDH2/NR1H3/FFAR4/SYTL4/RABGEF1/BTN2A2/CPTP/F2R/PPP1R11/TLR8/SRGN/APOA1/TNFRSF4/FRMD4A/CD34/SYT4/NDUFAF2/MAP4K4/C5AR2/CX3CL1/PFKL/NR1H4/TLR6/PSMD9/C1QTNF3/GHRL/RHBDF1	71
BP	GO:0051235	maintenance of location	147/7096	330/18670	0.008344	0.05193	0.03871	SLC8A1/S100A9/S100A8/HTR2B/EZR/PTPN6/HEXB/SUN2/LYN/PINK1/STARD4/MCOLN1/BARD1/PTPN2/TPCN1/DIAPH1/GM2A/PPARD/FLNA/KEAP1/FBXW7/PLIN2/G3BP2/CXCL9/SCARB1/SQLE/CXCL11/PTPRC/TMSB10/P2RX7/SOAT1/TNF/NFKBIA/CXCL10/NFKB1/PKD2/APOE/SUPT7L/VPS13A/ALKBH7/TWF2/TLN1/TGFB1/ITPR1/FFAR2/FTL/CD36/PTK2B/MYO5A/LEP/NR1H2/LATS1/CORO1A/P2RY6/RYR1/GOPC/HSPA5/CDK5/SP100/ABL1/PAFAH1B1/ABCA1/GSTO1/IL1B/PLCG2/PML/ACACB/EHD1/DMD/SIRT1/ATP7B/TRPM2/DGAT2/IL6/LCK/CLMN/GPAA1/CCR5/ASPM/SRI/BBS4/SYNE2/RASA3/KDELR3/FTO/VPS13D/ANXA6/BAX/TLN2/ABCG1/NR1H3/PRKACA/B4GALNT1/GET4/KDELR2/CYBA/SHANK1/NFKBIE/SREBF2/MEST/MCOLN2/F2R/CALR/FLNB/INSIG1/CAMK2D/PLCB1/CEMIP/TXN/GPSM2/PPARA/SCIN/HSP90B1/LETM1/SRGN/APOA1/CASQ1/SPAG4/GAA/CAPN3/CASQ2/HRC/SLC30A2/BDKRB1/CD4/MXI1/TMEM38B/LACRT/LIME1/TOPORS/DAG1/SNCA/CX3CL1/CCL19/VSTM2A/RER1/ARL2BP/CHERP/ATP1A2/CCR7/MCOLN3/CER1/NRIP1/TONSL/OS9/NTSR1/ALB	147
BP	GO:0032868	response to insulin	123/7096	272/18670	0.008506	0.0527	0.03929	SH2B2/ATP6V0D2/SLC27A1/TLR2/PDK4/APPL2/SOCS3/LYN/TSC1/RETN/SRSF5/SRD5A1/ATP6AP1/PTPN2/CCND3/HADH/ATP6V1C1/ADIPOR1/STAT1/GSTP1/EGR1/C2CD5/ATP6V0C/SLC9A1/CISH/GSK3B/GAB1/RAB31/PIK3R3/KAT2B/GKAP1/PKM/RELA/PDK2/SLC2A8/EIF6/CDK4/PAK1/ENHO/MYO5A/PCK2/LEP/SYAP1/PRKCD/INSR/BAIAP2/TCIRG1/ZBTB7B/IGF1R/NCK1/CAT/ATP6V1A/TNFSF10/GCLC/IL1B/SIK2/SHC1/PHIP/RAB8A/ATP6V1G3/SIRT1/EIF4EBP2/FABP3/EGR2/ATP6V1B2/IRS2/CYFIP1/MYO1C/DENND4C/ATP6V1D/GCNT1/GRB10/KHK/PFKFB1/GNAI2/ATP6V0E2/SCAP/INPP5K/GPR21/SRSF6/RHOQ/CPEB1/KANK1/NDEL1/PPAT/GRB2/FOXO4/FER/GOT2/ATP6V1G2/HADHA/SERPINA12/RAB8B/SLC25A33/PPARA/KL/PRKAA1/PID1/SOCS1/SRSF4/CAD/ZNF106/OGT/YWHAG/SLA2/STXBP3/PRKCZ/MTOR/PRKCQ/HDAC5/TRPV4/ATP6V1B1/SMARCC1/APPL1/SOCS2/INPPL1/KLF15/NUCKS1/NR1H4/STXBP4/SESN2/CPEB2/FOXO3	123
BP	GO:0042100	B cell proliferation	48/7096	95/18670	0.008541	0.0527	0.03929	CDKN1A/BST1/LYN/MNDA/BCL6/CD40/MIF/PTPRC/CD74/TNFRSF21/CD320/TICAM1/CD22/IL7R/TNFSF13B/PRKCD/TLR4/CASP3/ABL1/SLC39A10/AHR/IL7/TYROBP/IRS2/CTLA4/ATM/BCL2/BAX/NFATC2/MS4A1/CLCF1/IFNK/CR2/CD300A/ADA/TFRC/TNFRSF13B/CHRNB2/TNFRSF4/CTPS1/PLCL2/GAPT/TNFRSF13C/GPR183/IKZF3/TIRAP/ATAD5/MEF2C	48
BP	GO:0019915	lipid storage	36/7096	68/18670	0.008564	0.0527	0.03929	HEXB/STARD4/PTPN2/GM2A/PPARD/FBXW7/PLIN2/SCARB1/SQLE/SOAT1/TNF/NFKBIA/NFKB1/APOE/ALKBH7/FFAR2/CD36/LEP/NR1H2/ABCA1/IL1B/ACACB/EHD1/SIRT1/DGAT2/IL6/FTO/ABCG1/NR1H3/B4GALNT1/SREBF2/MEST/PPARA/APOA1/VSTM2A/NRIP1	36
BP	GO:0006002	fructose 6-phosphate metabolic process	8/7096	10/18670	0.008605	0.0527	0.03929	TALDO1/FBP1/PFKM/PFKP/NFE2L1/GFPT1/GFPT2/PFKL	8
BP	GO:0016559	peroxisome fission	8/7096	10/18670	0.008605	0.0527	0.03929	PEX11A/PEX11G/FIS1/PEX19/DNM1L/PEX11B/SEC16B/ACOT8	8
BP	GO:0031340	positive regulation of vesicle fusion	8/7096	10/18670	0.008605	0.0527	0.03929	ANXA1/C2CD5/DOC2B/ANXA2P2/SYT9/SYT1/KIF5B/ANXA2	8
BP	GO:0033210	leptin-mediated signaling pathway	8/7096	10/18670	0.008605	0.0527	0.03929	STAT3/ADIPOR1/LEP/BBS2/SIRT1/MKKS/BBS4/UGCG	8
BP	GO:0035646	endosome to melanosome transport	8/7096	10/18670	0.008605	0.0527	0.03929	CD63/BLOC1S6/ANKRD27/RAB32/RAB38/BLOC1S3/AP1G1/AP1M1	8
BP	GO:0043485	endosome to pigment granule transport	8/7096	10/18670	0.008605	0.0527	0.03929	CD63/BLOC1S6/ANKRD27/RAB32/RAB38/BLOC1S3/AP1G1/AP1M1	8
BP	GO:0048757	pigment granule maturation	8/7096	10/18670	0.008605	0.0527	0.03929	CD63/BLOC1S6/ANKRD27/RAB32/RAB38/BLOC1S3/AP1G1/AP1M1	8
BP	GO:0071501	cellular response to sterol depletion	8/7096	10/18670	0.008605	0.0527	0.03929	FBXW7/ARHGEF10L/ERLIN1/ZBTB7B/ERLIN2/SCAP/INSIG1/EIF2A	8
BP	GO:0072610	interleukin-12 secretion	8/7096	10/18670	0.008605	0.0527	0.03929	LILRA5/LILRB1/LGALS9/TLR8/MAPK11/FOXP1/CCL19/CCR7	8
BP	GO:0097048	dendritic cell apoptotic process	8/7096	10/18670	0.008605	0.0527	0.03929	LYN/LILRB1/CXCL12/AXL/RAPGEF2/LGALS9/CCL19/CCR7	8
BP	GO:1900122	positive regulation of receptor binding	8/7096	10/18670	0.008605	0.0527	0.03929	HFE/NRP1/MMP9/PLCL1/ANXA2P2/PLCL2/ANXA2/HOXA3	8
BP	GO:2000668	regulation of dendritic cell apoptotic process	8/7096	10/18670	0.008605	0.0527	0.03929	LYN/LILRB1/CXCL12/AXL/RAPGEF2/LGALS9/CCL19/CCR7	8
BP	GO:0006378	mRNA polyadenylation	25/7096	44/18670	0.008614	0.0527	0.03929	PCF11/ZC3H14/PAF1/CSTF3/SYMPK/CPSF3/CDK9/CLP1/PAPOLA/SCAF8/MTPAP/SNRPA/FIP1L1/CPEB1/CPEB3/LEO1/RNF20/AHCYL1/CPSF2/CCNT1/APP/CDC73/CPSF1/PNPT1/CPSF7	25
BP	GO:0042987	amyloid precursor protein catabolic process	25/7096	44/18670	0.008614	0.0527	0.03929	IGF1/LYN/TNF/PSENEN/APOE/CASP3/TMED10/CLN3/AGER/CLU/FLOT2/PSEN2/ABCG1/ABCA7/IFNGR1/PSEN1/IFNG/PIN1/APP/GSAP/APH1A/PICALM/ROCK2/BIN1/EFNA3	25
BP	GO:1903214	regulation of protein targeting to mitochondrion	25/7096	44/18670	0.008614	0.0527	0.03929	RAC2/PINK1/HPS4/SIRT4/FBXW7/CSNK2A2/UBE2D3/HTRA2/ATG13/LRRK2/RHOU/PDCD5/ARIH2/ABLIM3/MICALL2/UBL4B/LMAN1/SREBF2/FZD5/HSPA1L/PRKAA1/PARL/SH3GLB1/UBL5/BAP1	25
BP	GO:0019320	hexose catabolic process	31/7096	57/18670	0.008641	0.05276	0.03934	HK3/PGK1/PFKM/PFKP/GAPDH/GALM/ALDH1A1/GALE/FUT4/FUT7/PGAM1/LRP5/PKM/GALK1/TPI1/ALDOC/ENO1/ALDOA/GPI/SLC25A12/PGM2/KHK/FUT6/GALT/FOXK2/PFKFB2/ENO2/BAD/ADPGK/GLYCTK/PFKL	31
BP	GO:0031294	lymphocyte costimulation	31/7096	57/18670	0.008641	0.05276	0.03934	FYN/PTPN6/LYN/CSK/TNFRSF14/MAP3K8/CD320/DPP4/PAK1/TNFSF13B/PAK2/ICOSLG/EFNB1/RAC1/LCK/CTLA4/PDCD1LG2/LGALS1/GRB2/CD274/ICOS/VAV1/TNFSF4/CD5/TNFRSF13C/CD80/CCL19/CCR7/CD3E/PDCD1/CD24	31
BP	GO:0006400	tRNA modification	44/7096	86/18670	0.00871	0.05308	0.03957	TRMT6/SEPHS2/DPH3/ALKBH1/FTSJ1/TPRKB/OSGEPL1/ELP4/TRMT5/TRMT1/TYW3/BCDIN3D/DUS2/LCMT2/TRMT112/TRMT61B/NSUN2/TRMT1L/PUS1/NAT10/OSGEP/THUMPD1/METTL1/ELP3/METTL8/HSD17B10/QTRT1/WDR4/ALKBH8/THUMPD2/MOCS3/TRMT11/THUMPD3/SSB/ELP2/MTFMT/ADAT2/MTO1/DUS1L/TRMT10C/PUS7/GTPBP3/NSUN6/AARS2	44
BP	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	44/7096	86/18670	0.00871	0.05308	0.03957	ITPRIP/PEA15/SKIL/BLOC1S2/DEDD/TNFRSF10A/PMAIP1/TNFAIP3/FAS/TNF/HMOX1/TMC8/HGF/FEM1B/TNFRSF10C/SP100/TNFSF10/CASP8/DEDD2/ARHGEF2/DAPK1/TRADD/RAF1/DDX3X/BMP5/BCL2/BAX/SERPINE1/HMGB2/CRADD/RFFL/TNFRSF10B/BRCA1/FADD/TRAF2/BAD/FAIM2/MOAP1/ZSWIM2/DIABLO/GPX1/FAIM/BMPR1B/DAXX	44
BP	GO:0062013	positive regulation of small molecule metabolic process	73/7096	153/18670	0.008768	0.05339	0.0398	IGF1/ANXA1/PINK1/PGK1/POR/STARD4/STAT3/PTPN2/PFKFB3/PTGS2/PMAIP1/RDH10/SLC45A3/P2RX7/TNF/CD74/ELOVL5/NUPR1/NFKB1/LPGAT1/KAT2B/DYRK2/HIF1A/PTAFR/ISCU/PPP1R3E/NR1H2/INSR/P2RY6/DDB1/ENO1/IL1B/SIRT1/DGAT2/IRS2/PDGFB/PFKFB4/PPARGC1A/FGF1/MLYCD/APOA5/SLC25A12/MYOG/ADORA2B/PFKFB1/ABCG1/NR1H3/CPT1A/PGK2/PFKFB2/ARNT/PPARA/KAT2A/PRKAA1/PSEN1/PID1/TREM2/IFNG/NR4A3/ESRRB/ZBTB20/VCP/TAZ/APP/SNCA/ABCD1/CD244/GCG/ADCYAP1R1/NR1H4/WDR5/P2RY1/NTSR1	73
BP	GO:0006900	vesicle budding from membrane	51/7096	102/18670	0.008856	0.05387	0.04016	S100A10/SERPINA1/F5/DNM3/MCFD2/KLHL12/CTSC/SEC22B/P2RX7/CD59/ANKRD28/SAR1B/TRAPPC6A/CSNK1D/PPP6R1/CNIH3/TRAPPC5/CTSZ/ARFGAP3/TMED10/BET1/VAPB/GOSR2/STX5/SAR1A/ARF1/PPP6C/DNM1/TRAPPC6B/TRAPPC9/GOLPH3L/NAPA/DNM2/TBC1D20/COL7A1/LMAN1/PEF1/INSIG1/SEC23IP/TRAPPC2L/AP3B1/ANXA2P2/TRAPPC3/SCFD1/AP2M1/ANXA2/PICALM/PREB/SEC24A/SEC31B/SEC16B	51
BP	GO:0008064	regulation of actin polymerization or depolymerization	84/7096	179/18670	0.008887	0.05401	0.04027	MYADM/CDC42EP4/VASP/ARF6/HCK/RHOBTB1/PLEKHG2/TMSB10/SPIRE1/IQGAP2/ACTR2/CXCL12/TMOD3/LIMA1/HCLS1/EVL/TWF2/RDX/PFN1/CDC42EP2/PTK2B/CFL2/CAPZA2/SWAP70/PRKCD/LATS1/GMFG/CORO1A/BAIAP2/ARFGEF1/CAPG/NCK1/FCHSD1/ARPC1A/CAPZA1/MKKS/SH3BP1/ARPIN/SPTBN1/ARPC1B/CDC42EP3/CYFIP1/MYO1C/CORO1B/BBS4/ARF1/ARPC5L/COTL1/AVIL/CFL1/KANK1/TRIOBP/ARHGAP18/ADD3/GRB2/PLEK/JMY/ACTR3B/FER/SEMA5A/DMTN/ACTR3/LMOD3/SCIN/PREX1/SLIT2/CCL26/ARPC4/SPTA1/SPTBN2/ARPC2/KANK3/MTOR/RHOA/PICK1/SNX9/CCR7/WAS/RHOBTB2/CCL24/BIN1/NCKAP1/FCHSD2/FMN1	84
BP	GO:0043523	regulation of neuron apoptotic process	97/7096	210/18670	0.009037	0.05487	0.04091	NQO1/ITGAM/FYN/CX3CR1/GRN/NR4A2/PINK1/GCLM/AIFM1/SOD1/ALKBH1/FBXW7/LGMN/CEBPB/JAK2/ADAM8/TNF/HMOX1/NUPR1/KRAS/APOE/BTG2/ATF4/AXL/STXBP1/FIS1/ARRB1/HIF1A/WFS1/PTK2B/CORO1A/MCL1/ITSN1/FZD9/CDK5/CASP3/HRAS/NMNAT1/GCLC/CTSZ/ZPR1/CLN3/MAP3K12/SRPK2/LRP1/TYROBP/G6PD/EGLN3/PPARGC1A/ATM/SNX6/BCL2L11/NRP1/BCL2/KDM2B/BAX/HDAC4/CASP2/CLCF1/SYNGAP1/AKT1S1/MAP3K11/UNC5B/PITX3/LIG4/BHLHB9/F2R/NSMF/CNTF/PSEN1/UBE2M/CNTFR/STAMBP/MAP2K4/TGFB3/FAIM2/NR4A3/HYOU1/PIN1/HSP90AB1/LANCL1/SET/TERT/RHOA/TYRO3/SNCA/CX3CL1/SIGMAR1/PTPRZ1/SLC30A10/ERBB3/KIF14/FOXO3/NTRK2/MEF2C/OXR1/GDF5	97
BP	GO:0033003	regulation of mast cell activation	24/7096	42/18670	0.009077	0.05499	0.04099	RAC2/LYN/PLSCR1/IL4R/HMOX1/C12orf4/CD226/STXBP1/STXBP2/FGR/CD300LF/ADORA2B/UNC13D/CD300A/LGALS9/FER/RABGEF1/CNR2/IL13RA2/CD84/TSLP/NR4A3/SNX4/FOXF1	24
BP	GO:0006486	protein glycosylation	117/7096	258/18670	0.009082	0.05499	0.04099	TMTC3/PGM3/EXTL2/MCFD2/MGAT2/DAD1/B3GNT8/VEGFB/CHP1/MGAT5/MAN1C1/POMGNT2/LFNG/GALNT14/IL15/FUT4/EXT2/EXT1/FUT7/TET2/MGAT4B/B3GNT2/MAN2A2/STT3A/NAGPA/B4GALT6/ARFGEF1/POGLUT1/ALG2/KRTCAP2/B3GNT5/TRAK2/OST4/PMM2/ST6GALNAC4/UBE2J1/ST3GAL2/GALNT7/LMF1/MUC2/B3GALT6/FKRP/ALG6/UBE2G2/SDF2L1/DPY19L4/DPM1/GALNT6/TMTC2/SERP1/GCNT1/RPN2/GALNT12/DOLK/MUC1/GALNT10/STT3B/NUDT14/ALG12/ALG10/MGAT3/MAN1B1/ASGR2/LMAN1/DOLPP1/FUT6/B4GALT5/ST8SIA4/MGAT5B/ALG13/MAN1A2/MOGS/POMT1/TUSC3/TMEM258/SLC35C1/NUS1/DHDDS/GALNT9/SRD5A3/ST6GALNAC5/XXYLT1/GFPT1/POMT2/PSEN1/DPM3/B3GNT4/GGTA1P/ST3GAL1/DPY19L2/MUC6/OGT/TRAK1/GCNT2/ST6GALNAC3/B3GAT3/MUCL1/ST6GALNAC6/COG7/ASGR1/VCP/C1GALT1/B3GALT5/GFPT2/B4GALT1/GALNT1/ALG14/EDEM3/ST8SIA1/DDOST/ST3GAL5/DPAGT1/DPY19L2P2/ALG8/TET1/ALG3/GALNT15	117
BP	GO:0043413	macromolecule glycosylation	117/7096	258/18670	0.009082	0.05499	0.04099	TMTC3/PGM3/EXTL2/MCFD2/MGAT2/DAD1/B3GNT8/VEGFB/CHP1/MGAT5/MAN1C1/POMGNT2/LFNG/GALNT14/IL15/FUT4/EXT2/EXT1/FUT7/TET2/MGAT4B/B3GNT2/MAN2A2/STT3A/NAGPA/B4GALT6/ARFGEF1/POGLUT1/ALG2/KRTCAP2/B3GNT5/TRAK2/OST4/PMM2/ST6GALNAC4/UBE2J1/ST3GAL2/GALNT7/LMF1/MUC2/B3GALT6/FKRP/ALG6/UBE2G2/SDF2L1/DPY19L4/DPM1/GALNT6/TMTC2/SERP1/GCNT1/RPN2/GALNT12/DOLK/MUC1/GALNT10/STT3B/NUDT14/ALG12/ALG10/MGAT3/MAN1B1/ASGR2/LMAN1/DOLPP1/FUT6/B4GALT5/ST8SIA4/MGAT5B/ALG13/MAN1A2/MOGS/POMT1/TUSC3/TMEM258/SLC35C1/NUS1/DHDDS/GALNT9/SRD5A3/ST6GALNAC5/XXYLT1/GFPT1/POMT2/PSEN1/DPM3/B3GNT4/GGTA1P/ST3GAL1/DPY19L2/MUC6/OGT/TRAK1/GCNT2/ST6GALNAC3/B3GAT3/MUCL1/ST6GALNAC6/COG7/ASGR1/VCP/C1GALT1/B3GALT5/GFPT2/B4GALT1/GALNT1/ALG14/EDEM3/ST8SIA1/DDOST/ST3GAL5/DPAGT1/DPY19L2P2/ALG8/TET1/ALG3/GALNT15	117
BP	GO:0045930	negative regulation of mitotic cell cycle	150/7096	338/18670	0.009101	0.05505	0.04104	KLF4/TPRA1/DUSP1/CDKN2D/CDKN1A/MAD2L2/GPNMB/PSMB9/CUL1/TIMP2/BCL6/PSMB8/DYNC1LI1/ZNF655/HECA/RGCC/HUS1B/NABP1/PSMA5/TNF/SLFN11/PSMD11/EZH2/SPDL1/PKD2/GIGYF2/PSME1/BTG2/GPR132/CDK4/TGFB1/TAOK3/ZNF830/PSMB10/PSMA1/PSMA4/NAA10/SYF2/SETMAR/CDKN2B/PLK2/SFN/KLHL22/HRAS/ABL1/CDK5RAP2/PSMB1/PSMC4/TOM1L1/DONSON/PML/PSMD13/CDK2AP2/PSMB3/TOM1L2/BMP7/TIPIN/CCND1/ZNF207/LCMT1/PSMB5/PSMD6/ATM/TNKS1BP1/BTG3/BUB3/MUC1/PSMC3/BTG1/CTDSPL/PLK3/PSME3/NACC2/RAD17/NDC80/BCL2/PCNA/BMP4/BAX/PSMC6/ZWILCH/CRADD/CASP2/CTDSP1/RFWD3/CDKN1B/CDKN2C/MAD2L1BP/TOP2B/CNOT4/FHL1/PLAGL1/GEN1/ARID3A/ZW10/INTS3/FOXO4/TICRR/BTN2A2/MIIP/E2F4/BRCA1/EGFR/CNOT7/GML/CTDSP2/MDM2/GADD45GIP1/PSMC1/ZFP36L2/CLSPN/WEE1/RPL24/RBL2/MTBP/DCUN1D3/PSMD8/PSMA2/RAD9A/FBXL7/TOPBP1/CDC20/PCID2/RB1/CNOT10/CARM1/JADE1/PSMC5/PSMC2/PSMB2/PSMD4/AURKAIP1/TRIAP1/AURKA/BRSK1/CDC73/RBX1/SOX4/PNPT1/IK/PSMD1/PRMT1/CHFR/PSMB4/ZFYVE19/PSMD9/PSMD3/E2F8/TOP2A/DDIAS	150
BP	GO:0000045	autophagosome assembly	47/7096	93/18670	0.009144	0.05517	0.04113	ATG7/PINK1/ATG3/C9orf72/FEZ2/ULK2/ATG14/SEC22B/NUPR1/CHMP4B/RAB23/MAP1LC3A/ATG101/TP53INP2/UBXN2B/TMEM41B/RAB3GAP1/NSFL1C/ATG13/WIPI1/NPRL3/RAB33B/LRRK2/MAP1LC3C/ATG9A/PHF23/UBQLN2/ATG4B/PACS2/RAB5A/ATG2B/WDR45B/ULK1/PSEN1/MTMR3/STX12/SH3GLB1/IFT20/SMCR8/NPRL2/ATG16L2/GABARAPL1/SCFD1/RNF5/ATG4A/TRAPPC8/ATG12	47
BP	GO:0048207	vesicle targeting, rough ER to cis-Golgi	35/7096	66/18670	0.009147	0.05517	0.04113	SERPINA1/F5/MCFD2/KLHL12/CTSC/SEC22B/CD59/ANKRD28/SAR1B/TRAPPC6A/CSNK1D/PPP6R1/CNIH3/TRAPPC5/CTSZ/TMED10/BET1/GOSR2/STX5/SAR1A/PPP6C/TRAPPC6B/TRAPPC9/NAPA/TBC1D20/COL7A1/LMAN1/PEF1/SEC23IP/TRAPPC2L/TRAPPC3/SCFD1/PREB/SEC24A/SEC16B	35
BP	GO:0048208	COPII vesicle coating	35/7096	66/18670	0.009147	0.05517	0.04113	SERPINA1/F5/MCFD2/KLHL12/CTSC/SEC22B/CD59/ANKRD28/SAR1B/TRAPPC6A/CSNK1D/PPP6R1/CNIH3/TRAPPC5/CTSZ/TMED10/BET1/GOSR2/STX5/SAR1A/PPP6C/TRAPPC6B/TRAPPC9/NAPA/TBC1D20/COL7A1/LMAN1/PEF1/SEC23IP/TRAPPC2L/TRAPPC3/SCFD1/PREB/SEC24A/SEC16B	35
BP	GO:0032613	interleukin-10 production	30/7096	55/18670	0.009196	0.05537	0.04128	NOD2/TLR2/DLL1/CLEC7A/LILRA5/TNFRSF21/LILRB1/HGF/PRKCD/IL20RB/TLR4/IDO1/AGER/ISG15/HMGB1/TYROBP/TIGIT/PDCD1LG2/CD47/TRIB2/CD274/LGALS9/TNFSF4/TREM2/TSLP/CD34/IL12B/PRKCZ/CD83/IL23A	30
BP	GO:0043551	regulation of phosphatidylinositol 3-kinase activity	30/7096	55/18670	0.009196	0.05537	0.04128	KLF4/FPR2/NOD2/SOCS3/LYN/FLT1/WDR91/ATG14/WDR81/CISH/PIK3R3/TGFB1/SOCS5/PTK2B/PIK3IP1/FLT3/SOCS6/FGR/PIK3R6/P2RY12/SOCS7/PDGFB/EPHA8/PTK2/SOCS1/SLA2/CCL19/CCKBR/CCR7/SOCS2	30
BP	GO:0045445	myoblast differentiation	43/7096	84/18670	0.009324	0.05603	0.04177	IGF1/EPAS1/DLL1/MAPK12/RBPJ/PPARD/KLHL41/CXCL9/TNF/IFRD1/CXCL10/HMGCR/TGFB1/SRA1/SRF/NRG1/MBNL1/FLT3LG/HIF1AN/MBNL3/FLOT2/BTG1/MYOG/BMP4/PLEKHM3/KCNAB1/LGALS1/NMRK2/MAP3K5/PLCB1/IL18/TCF7L2/CAPN3/RB1/PITX1/HINFP/CMTM5/WNT10B/GREM1/BOC/FGF6/MEF2C/MYF6	43
BP	GO:0051492	regulation of stress fiber assembly	43/7096	84/18670	0.009324	0.05603	0.04177	S100A10/PTGER4/STMN1/FHOD1/TSC1/ARAP1/SORBS3/RHOC/S1PR1/RGCC/SLC9A1/ARHGEF10L/EVL/PFN1/PAK1/ABL1/PPM1F/MKKS/RAC1/ARHGAP6/BBS4/LIMCH1/NRP1/TPM1/INPP5K/CD47/LPAR1/PXN/CLASP2/APOA1/TGFB3/SYNPO2L/TACSTD2/TMEFF2/MTOR/RHOA/ITGB1BP1/MET/WAS/ROCK2/ASAP3/SERPINF2/ALMS1	43
BP	GO:0034446	substrate adhesion-dependent cell spreading	50/7096	100/18670	0.009483	0.05693	0.04244	MYADM/S100A10/FN1/GBP1/ITGB7/NEDD9/FLNA/CIB1/ACTN4/LAMB2/AKIP1/PEAK1/AXL/PARVB/LAMC3/ITGA4/LAMB3/VAMP3/ABL1/CRK/RAC1/DOCK5/PTK2/SRGAP2/NRP1/DNM2/MICALL2/UNC13D/KANK1/TRIOBP/FER/DMTN/CORO1C/CALR/PXN/C1QBP/RCC2/FZD4/PREX1/MERTK/APOA1/ITGA8/MEGF9/FZD7/TACSTD2/ARPC2/TYRO3/LIMS1/ITGB1BP1/KIF14	50
BP	GO:0071470	cellular response to osmotic stress	23/7096	40/18670	0.009552	0.05724	0.04267	OXSR1/AKR1B1/PTGS2/PKD2/MBIP/CASP3/RELB/XRCC5/ARHGEF2/LRRC8D/DDX3X/EFHD1/MICU1/YBX3/MYLK/LETM1/BAD/XRCC6/CAPN3/SERPINB6/TRPV4/LRRC8E/SLC12A6	23
BP	GO:0098534	centriole assembly	23/7096	40/18670	0.009552	0.05724	0.04267	NUP62/KAT2B/TRIM37/SASS6/PLK2/NPM1/CDK5RAP2/KIAA0753/CEP76/CCDC78/SPICE1/CHMP2A/CEP152/VPS4B/CEP63/E2F4/BRCA1/CETN1/CETN2/KAT2A/CEP120/C2CD3/ALMS1	23
BP	GO:0043550	regulation of lipid kinase activity	34/7096	64/18670	0.009769	0.05843	0.04356	KLF4/FPR2/NOD2/SOCS3/LYN/FLT1/WDR91/ATG14/WDR81/CISH/PIK3R3/TGFB1/SOCS5/PTK2B/PIK3IP1/FLT3/SOCS6/FGR/PIK3R6/P2RY12/SOCS7/PDGFB/EPHA8/PTK2/EEF1A2/SOCS1/RBL2/RB1/SLA2/CCL19/NRBF2/CCKBR/CCR7/SOCS2	34
BP	GO:0046782	regulation of viral transcription	34/7096	64/18670	0.009769	0.05843	0.04356	TRIM32/ZFP36/CHD1/TRIM13/IFITM3/TFAP4/TAF11/CCL5/DHX9/GTF2F2/MDFIC/POLR2L/TRIM11/CTDP1/CDK9/POLR2H/PSMC3/TRIM21/TARBP2/INPP5K/SUPT4H1/RSF1/GTF2F1/POLR2F/POLR2D/MID2/POLR2K/NELFCD/HPN/CCNT1/CCL4/POLR2I/NUCKS1/TARDBP	34
BP	GO:0042073	intraciliary transport	29/7096	53/18670	0.009784	0.05847	0.04359	IFT172/TNPO1/IFT57/KIF3B/KIFAP3/PCM1/DYNLL2/CEP131/IFT80/WDR19/BBS12/IFT46/RPGR/IFT52/MAK/HSPB11/DYNC2LI1/DYNLRB1/DYNLRB2/LCA5/IFT20/KIF17/WDR60/IFT22/WDR35/TRAF3IP1/IFT74/TTC30B/IFT81	29
BP	GO:0010639	negative regulation of organelle organization	173/7096	395/18670	0.00995	0.05941	0.04429	IGF1/MYADM/LILRB2/DUSP1/VAT1/SPI1/STMN1/ATG7/PINK1/MAD2L2/SKI/LMNA/SLC35F6/ARAP1/RNF41/S1PR1/SIRT4/DYNC1LI1/FEZ2/CIB1/SEC22B/MCM2/RGCC/TMSB10/NUPR1/SPDL1/TMEM14A/ERCC4/PRELID1/TMOD3/KAT2B/LIMA1/CHMP4B/TRIM37/RAD1/HIGD1A/TWF2/RDX/SIN3A/ZNF451/PFN1/HGF/MAP4/CAPZA2/SWAP70/PRKCD/GMFG/CORO1A/ARFGEF1/MPV17L/HTRA2/CAPG/NAA10/FZD9/SETMAR/HNRNPA1/KLHL22/NPM1/OMA1/CDK5RAP2/XRCC5/TOM1L1/HMGA1/UBR5/ARHGEF2/CAPZA1/DCP2/ANKRD27/MAPRE1/CLU/SIRT1/TOM1L2/BMP7/MKKS/ARPIN/SPTBN1/CDH5/SLC25A5/LRRK2/PPARGC1A/FLCN/BCOR/ESPL1/NAT10/ZNF207/LCMT1/CORO1B/ARHGAP6/ATM/BBS4/BUB3/PHF23/FNIP1/MAK/HNRNPC/NDC80/XRN1/DNM2/BMP4/XRCC1/AVIL/CHMP2A/INPP5K/NOC2L/ERCC1/KANK1/TRIOBP/ATAD2B/ADD3/GEN1/TBC1D7/LMAN1/USP30/ZW10/SHANK1/DMTN/KDM4D/DNM1L/MOS/INSIG1/CLASP2/LMOD3/BRCA1/MUL1/CAV3/SCIN/ACAA2/SLIT2/TUBB4A/KAT2A/TCHP/RTEL1/ACD/SMCR8/CTC1/KATNB1/MTBP/ASF1A/SPTA1/CDC20/GNL3L/PCID2/SCFD1/SPTBN2/CLEC16A/TACSTD2/SET/TMEFF2/LIG3/KANK3/SYT4/GPX1/AURKAIP1/NAV3/TRIAP1/PICK1/SNCA/CLIP3/POT1/TTBK2/IAPP/MET/PAX5/IK/FGF13/WAS/UBE2B/SHANK3/HORMAD1/TOP2A/TET1/CCNF/TAF7	173
BP	GO:0071158	positive regulation of cell cycle arrest	42/7096	82/18670	0.009983	0.05955	0.04439	CDKN1A/RGCC/PKD2/BTG2/TGFB1/PLK2/SFN/PML/UHRF2/ATM/TNKS1BP1/MIR34A/MUC1/MYOG/PLK3/MYBBP1A/PCNA/BAX/CRADD/ID2/CASP2/CDKN1B/PRKACA/CNOT4/PLAGL1/ARID3A/FOXO4/MED25/E2F4/BRCA1/CNOT7/GML/MDM2/RBL2/PPP2R5B/CNOT10/CARM1/TRIAP1/AURKA/SOX4/PRMT1/E2F8	42
BP	GO:2001056	positive regulation of cysteine-type endopeptidase activity	71/7096	149/18670	0.009994	0.05956	0.0444	S100A9/S100A8/FYN/CLEC7A/BCL10/AIFM1/GRAMD4/CTSD/NLRP3/TNFRSF10A/PMAIP1/LGMN/MYC/NLRP12/JAK2/FAS/BCAP31/TNF/IFT57/AIM2/FIS1/ARRB1/TFAP4/HTRA2/CYFIP2/TNFSF10/CASP8/DAPK1/PML/CASP5/HMGB1/TRADD/PPM1F/SIRT1/TTBK1/LCK/EGLN3/PDCD5/DDX3X/PRR7/BCL2L11/P2RX1/MEFV/BAX/CRADD/CASP1/KHDC1/LGALS9/ST20/MAP3K5/F2R/TNFRSF10B/MUL1/FADD/TRAF2/CASP4/COL4A3/BAD/DAP/NLRP1/ST18/NLRP2/WDR35/DIABLO/F3/VCP/RHOA/SNCA/MALT1/BAK1/SOX7	71
BP	GO:0048675	axon extension	59/7096	121/18670	0.01003	0.0597	0.04451	RTN4R/FN1/DPYSL2/WNT5A/C9orf72/SEMA4B/RAB11A/ULK2/LAMB2/ALCAM/VCL/IFRD1/APOE/GSK3B/CXCL12/TWF2/PPP3CB/SIN3A/PAK1/MEGF8/SRF/SEMA4A/VEGFA/USP9X/CDK5/TNFRSF12A/ABL1/PAFAH1B1/GDI1/SEMA4C/SEMA4D/LRP1/CYFIP1/SEMA6B/NRP1/DISC1/SEMA3B/DNM2/L1CAM/NRP2/NDEL1/OLFM1/WDR36/SEMA5A/ULK1/SLIT2/DVL1/SEMA5B/POU4F3/MAP3K13/RUFY3/PLXNA3/HSP90AB1/RTN4/MACF1/TRPV2/TRIM46/BMPR2/SLIT3	59
BP	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	49/7096	98/18670	0.01015	0.06029	0.04495	CTSF/CTSD/KLC1/AP1B1/DYNC1LI1/CTSS/LGMN/CD74/KIF3B/OSBPL1A/KIFAP3/SAR1B/CAPZA2/DYNLL2/TRAF6/CENPE/HLA-DPB1/HLA-DPA1/CAPZA1/KIF4A/HLA-DMB/HLA-DOB/KIF2A/HLA-DRA/AP1M2/HLA-DMA/ARF1/AP2A2/DNM2/DCTN2/LAG3/AP2S1/CTSV/CTSE/CANX/AP2A1/AP1S3/AP1G1/HLA-DQB2/KIF2C/AP1M1/SPTBN2/DYNC1LI2/KLC2/AP2M1/DCTN6/DCTN5/SEC24A/HLA-DOA	49
BP	GO:0030038	contractile actin filament bundle assembly	49/7096	98/18670	0.01015	0.06029	0.04495	S100A10/PTGER4/STMN1/FHOD1/TSC1/ARAP1/SORBS3/ITGB5/RHOC/S1PR1/RGCC/SLC9A1/ARHGEF10L/EVL/PFN1/ARRB1/PAK1/PHACTR1/PTK2B/SRF/ABL1/PPM1F/MKKS/RAC1/ARHGAP6/BBS4/LIMCH1/ZYX/NRP1/TPM1/INPP5K/CD47/LPAR1/PXN/CLASP2/APOA1/TGFB3/SYNPO2L/TACSTD2/TMEFF2/MTOR/RHOA/ITGB1BP1/MET/WAS/ROCK2/ASAP3/SERPINF2/ALMS1	49
BP	GO:0043149	stress fiber assembly	49/7096	98/18670	0.01015	0.06029	0.04495	S100A10/PTGER4/STMN1/FHOD1/TSC1/ARAP1/SORBS3/ITGB5/RHOC/S1PR1/RGCC/SLC9A1/ARHGEF10L/EVL/PFN1/ARRB1/PAK1/PHACTR1/PTK2B/SRF/ABL1/PPM1F/MKKS/RAC1/ARHGAP6/BBS4/LIMCH1/ZYX/NRP1/TPM1/INPP5K/CD47/LPAR1/PXN/CLASP2/APOA1/TGFB3/SYNPO2L/TACSTD2/TMEFF2/MTOR/RHOA/ITGB1BP1/MET/WAS/ROCK2/ASAP3/SERPINF2/ALMS1	49
BP	GO:0060249	anatomical structure homeostasis	190/7096	437/18670	0.01018	0.0604	0.04503	EPAS1/SPATA7/NOD2/SIGLEC15/CCR2/PIP/TRIM32/RAC2/PDK4/ACP5/CSK/SOD1/DRAM2/ATP6AP1/AKR1B1/TPP1/BARD1/PFKM/SPP1/TNFAIP3/S1PR1/LIPA/SNX10/MYC/SLC22A5/LAMP2/HUS1B/CTSK/LDB1/P2RX7/ADAM8/ERCC6/GIGYF2/KRAS/ERCC4/MAP3K4/BBS10/PBLD/CHMP4B/ACTB/TGFB1/SMC5/CLN8/HIF1A/ZNF830/SMC6/HSPB1/PTK2B/PRDX1/CFL2/RPA1/SRF/PKIB/CORO1A/TRAF6/NAF1/FLT3LG/TCIRG1/PIWIL4/IL20RB/TLR4/TP53INP2/FGGY/HNRNPA1/VEGFA/CDK5/CLCN3/SP100/PRIM2/HNRNPA2B1/POLD4/ALDOA/TEP1/LTBP3/NSMCE2/XRCC5/CYTL1/DCP2/PML/POLD2/TNFRSF11A/DMD/BBS2/MUC2/BBS12/IL7/MKKS/HOMER1/RAC1/PLEKHM1/IL6/RDH12/NAT10/RFC3/HAAO/PTGES3/ATM/TNKS1BP1/BBS4/MAPKAPK5/TMEM64/NPHP4/MAK/P2RX1/NHP2/HNRNPC/STRAP/CCNE1/XRN1/BCL2/PCNA/XRCC1/PARP3/FH/BAX/ERCC1/GAR1/ADRB2/WDR36/HNRNPD/MKS1/CCT4/F2R/FBXO4/DCLRE1A/LCA5/ANKRD11/CCT8/EGFR/ATR/CAV3/COL2A1/USP7/TFRC/MAP1A/PRKAA1/DCSTAMP/MAPK1/RTEL1/TELO2/P2RY4/ACD/MUC6/EXO1/CTC1/POLD1/XRCC6/GAA/DCLRE1C/CAPN3/NXNL1/CLDN18/GNL3L/GCNT2/CD34/HSP90AB1/RB1/LACRT/POLA1/POLA2/TERT/ESRRB/CSF1R/PRKCQ/CDH3/TYRO3/RAB3D/CX3CL1/POT1/IAPP/CIB2/LPCAT1/POLE4/TULP1/CCDC66/TMEM119/NOP10/GNL3/SMO/PNKP/PRKCA/FEN1/RECQL4/NEK7/RBP4/P2RY1/RP1/POC1B/ALB/UPF1	190
BP	GO:0006164	purine nucleotide biosynthetic process	134/7096	300/18670	0.01022	0.06058	0.04516	IGF1/CBFA2T3/HK3/PDK4/LDHA/PINK1/FBP1/PGK1/CBR4/VPS9D1/STAT3/PFKFB3/NUP62/NUP160/PFKM/PFKP/GAPDH/PANK2/NUP214/ACOT7/PAPSS1/ACSL5/SLC2A6/P2RX7/ELOVL5/NUPR1/AK3/PGAM1/AK2/PKM/PDK2/GALK1/EIF6/TPI1/ZBTB7A/TGFB1/GMPS/NUP85/HIF1A/SCD/SEH1L/PANK3/ADK/INSR/ALDOC/PRPSAP1/PANK1/GUK1/PAICS/NUP43/IMPDH1/ACSL4/ACLY/ENO1/DNAJC30/ALDOA/GSTZ1/TECR/POM121/MPC2/ACACB/OGDH/ELOVL7/GPI/ADCY7/PFKFB4/PPARGC1A/FLCN/MLYCD/ADCY1/DHTKD1/NME3/ACSL6/SLC25A12/LDHC/NME4/PRKAG2/MYOG/NCOR1/ADORA2B/PFKFB1/ATIC/ADCY3/NUP88/HDAC4/PAPSS2/NME1/NUP107/PDK1/PRPS1/PPAT/PDHB/FOXK2/DDIT4/AMPD2/PGK2/PFKFB2/ADA/ARNT/DLAT/PDP2/PPARA/NUP93/SLC25A13/PRKAA1/PSEN1/PDHA2/NUP205/ENO2/PID1/GUCY2D/SLC4A1/PRPS1L1/TREM2/NUP50/IFNG/PRKAG1/OGT/PDP1/PRPS2/ESRRB/ZBTB20/VCP/ADPGK/TAZ/APP/SNCA/ELOVL6/AMPD3/PDPR/PFKL/POM121C/AAAS/HSD17B12	134
BP	GO:0032271	regulation of protein polymerization	100/7096	218/18670	0.01028	0.06086	0.04537	MYADM/CDC42EP4/VASP/ARF6/STMN1/PINK1/HCK/RHOBTB1/PLEKHG2/TMSB10/SPIRE1/IQGAP2/ACTR2/TMOD3/HCLS1/EVL/PSRC1/TWF2/RDX/PFN1/CDC42EP2/PAK1/CLIP1/PTK2B/CAPZA2/PRKCD/LATS1/GMFG/CORO1A/BAIAP2/ARFGEF1/CAPG/NCK1/ABL1/FCHSD1/CDK5RAP2/ARPC1A/CAPZA1/MAPRE1/TPPP3/MKKS/RAC1/ARPIN/SPTBN1/TTBK1/ARPC1B/CDC42EP3/CDH5/CYFIP1/MYO1C/CORO1B/BBS4/ARF1/ARPC5L/COTL1/AVIL/CDKN1B/KANK1/TRIOBP/ARHGAP18/ADD3/RANGRF/GRB2/VDAC2/JMY/ACTR3B/FER/DMTN/SLC39A12/ACTR3/LMOD3/CAV3/SCIN/PREX1/SLIT2/CCL26/TUBB4A/ARPC4/SPTA1/SLAIN2/SPTBN2/ARPC2/KANK3/MTOR/NAV3/RHOA/PICK1/SNCA/CLIP3/SNX9/MET/CCR7/WAS/RHOBTB2/CCL24/TPPP/BIN1/NCKAP1/FCHSD2/FMN1	100
BP	GO:1901617	organic hydroxy compound biosynthetic process	122/7096	271/18670	0.01033	0.06114	0.04558	VDR/ASAH1/GCH1/NR4A2/POR/STARD4/WNT5A/CYP27A1/SOD1/AKR1B1/NFYC/GPAM/CYB5R1/OSBPL9/FAXDC2/PER2/SQLE/TNF/SLC7A11/IMPAD1/PCBD1/SCP2/AKR1C3/NFKB1/RAN/APOE/ZEB2/HMGCR/OSBPL1A/HMGCS1/PTAFR/IP6K1/RAPGEF2/SCD/PTK2B/MYO5A/PCK2/LEP/ERLIN1/P2RY6/CNBP/BMP2/SPTLC2/ACLY/ASIP/IL1B/PLCG2/PPIP5K2/ERLIN2/FDPS/SLC27A2/HSD17B4/QDPR/ACACB/ACOX2/SIRT1/PTS/G6PD/DAO/FGF1/ARV1/TM7SF2/APOA5/SPR/SPHK1/SLC25A12/MSMO1/LDHC/IDI1/PRKAG2/BMP5/PLCL1/SCAP/IMPA2/ABCG1/SC5D/CH25H/OSBPL2/PLEK/ABCB11/SREBF2/CYB5R3/PLCD1/INSIG1/PLCB1/DHFR/DCT/TPH2/NUS1/DHDDS/ACAA2/IPPK/SRD5A3/PLCD4/ACER3/PRKAA1/HSD17B3/APOA1/CYP27B1/SNAI1/PLCL2/IFNG/DBH/PCBD2/MBTPS2/CDH3/SNCA/ELOVL6/OCA2/CD244/MBTPS1/KPNB1/CYP46A1/APPL1/CTNS/CACNA1H/ADCYAP1R1/NR1H4/P2RY1/NTSR1/ACOT8/IMPA1	122
BP	GO:0018393	internal peptidyl-lysine acetylation	76/7096	161/18670	0.01043	0.06123	0.04565	SPI1/POR/BAZ1A/DR1/LDB1/MORF4L2/HAT1/SUPT7L/KAT2B/MRGBP/TRIM16/TGFB1/SIN3A/ZNF451/JADE3/ARRB1/NCOA3/PCGF2/RUVBL2/RUVBL1/EPC2/MBIP/MSL3/MBD3/KAT7/YEATS4/SETD5/TAF5L/IL1B/KAT8/TAF12/CRTC2/SIRT1/NAA40/BRD8/TAF5/PPARGC1A/FLCN/MCRS1/MUC1/KAT5/ELP3/BRPF1/NOC2L/DPF2/CTCF/RSF1/PHF20/ZMPSTE24/TAF6L/BRCA1/ING3/KANSL1L/CLOCK/EPC1/KAT2A/PHF10/CPA4/TAF9B/EID1/OGT/MCM3AP/ING4/SET/JADE1/USP22/SNCA/MSL1/POLE4/TADA3/PAXIP1/ACTL6A/KAT6B/WDR5/TAF7/NAA60	76
BP	GO:0002903	negative regulation of B cell apoptotic process	9/7096	12/18670	0.01044	0.06123	0.04565	BCL10/BCL6/MIF/CD74/SLC39A10/IRS2/NOC2L/ADA/FOXP1	9
BP	GO:0006991	response to sterol depletion	9/7096	12/18670	0.01044	0.06123	0.04565	LYN/FBXW7/ARHGEF10L/ERLIN1/ZBTB7B/ERLIN2/SCAP/INSIG1/EIF2A	9
BP	GO:0009265	2'-deoxyribonucleotide biosynthetic process	9/7096	12/18670	0.01044	0.06123	0.04565	ADK/CDADC1/GUK1/CMPK2/TYMS/SHMT1/TBPL1/DCTD/DUT	9
BP	GO:0046385	deoxyribose phosphate biosynthetic process	9/7096	12/18670	0.01044	0.06123	0.04565	ADK/CDADC1/GUK1/CMPK2/TYMS/SHMT1/TBPL1/DCTD/DUT	9
BP	GO:0070486	leukocyte aggregation	9/7096	12/18670	0.01044	0.06123	0.04565	S100A9/S100A8/RAC2/CD44/IL1B/SEMA4D/BMP7/MSN/NR4A3	9
BP	GO:0071472	cellular response to salt stress	9/7096	12/18670	0.01044	0.06123	0.04565	AKR1B1/XRCC5/EFHD1/MICU1/LETM1/XRCC6/CAPN3/TRPV4/SLC12A6	9
BP	GO:1905244	regulation of modification of synaptic structure	9/7096	12/18670	0.01044	0.06123	0.04565	CTTNBP2/GRIPAP1/BAIAP2/ITSN1/ABL1/CAMKV/CYFIP1/FMR1/RHOA	9
BP	GO:2000341	regulation of chemokine (C-X-C motif) ligand 2 production	9/7096	12/18670	0.01044	0.06123	0.04565	KLF4/MBP/MIF/TNF/CD74/LRP1/MCOLN2/MAP2K5/TIRAP	9
BP	GO:0017038	protein import	92/7096	199/18670	0.01048	0.06142	0.04579	CDKN1A/APPL2/TXNIP/LMNA/TIMM23B/STAT3/NUP62/IPO13/PTGS2/CHP1/FLNA/PEX12/NUP214/LAMP2/NFKBIA/TNPO1/RAN/APOE/PEX16/HCLS1/TGFB1/RAB23/NUP85/NXT1/CBLB/CD36/LEP/PRKCD/PTTG1IP/HYAL2/KPNA4/DNAJC19/ZPR1/SNUPN/TIMM17A/UBR5/MMP12/MDFIC/POM121/PML/CLU/TIMM21/GRPEL1/MAVS/SNX33/LRRK2/NOLC1/PDCD5/IPO4/GRPEL2/BMP4/NUP88/TOMM22/TOMM40L/CSE1L/PEX13/NUP107/PEX3/PEX19/TOMM40/TOMM20/NXT2/RAB8B/TIMM22/PEX14/NUP93/AGK/IPO9/HSPA4/PSEN1/DNAJC15/IPO7/MAPK1/KPNA1/NUP50/IFNG/ARNTL/CHP2/TNPO3/RANBP6/NPAP1/PKIA/SPRN/TIMM50/MBTPS1/KPNB1/APPL1/SMO/TARDBP/TIMM44/POM121C/TIMM9	92
BP	GO:0050931	pigment cell differentiation	21/7096	36/18670	0.01052	0.06148	0.04584	HPS4/KITLG/ZEB2/MYO5A/CD63/MITF/BLOC1S6/ANKRD27/RAB32/RAB38/BCL2/BLOC1S3/AP1G1/HPS6/AP1M1/MREG/OCA2/RAB27A/GNA11/ADAMTS9/MEF2C	21
BP	GO:0051973	positive regulation of telomerase activity	21/7096	36/18670	0.01052	0.06148	0.04584	KLF4/MYC/MAP3K4/PKIB/NAF1/HNRNPA2B1/XRCC5/PTGES3/MAPKAPK5/PARM1/HNRNPD/CCT4/MAPK1/ACD/HSP90AB1/PRKCQ/POT1/GREM1/PNKP/NEK7/GRHL2	21
BP	GO:0090322	regulation of superoxide metabolic process	21/7096	36/18670	0.01052	0.06148	0.04584	ITGAM/FPR2/ACP5/GCH1/BST1/CLEC7A/SOD1/GNAI3/GSTP1/TNF/TGFB1/CD36/PRKCD/TYROBP/BMP7/AATF/GNAI2/CYBA/NFE2L2/DHFR/EGFR	21
BP	GO:0030832	regulation of actin filament length	84/7096	180/18670	0.01054	0.06158	0.04591	MYADM/CDC42EP4/VASP/ARF6/HCK/RHOBTB1/PLEKHG2/TMSB10/SPIRE1/IQGAP2/ACTR2/CXCL12/TMOD3/LIMA1/HCLS1/EVL/TWF2/RDX/PFN1/CDC42EP2/PTK2B/CFL2/CAPZA2/SWAP70/PRKCD/LATS1/GMFG/CORO1A/BAIAP2/ARFGEF1/CAPG/NCK1/FCHSD1/ARPC1A/CAPZA1/MKKS/SH3BP1/ARPIN/SPTBN1/ARPC1B/CDC42EP3/CYFIP1/MYO1C/CORO1B/BBS4/ARF1/ARPC5L/COTL1/AVIL/CFL1/KANK1/TRIOBP/ARHGAP18/ADD3/GRB2/PLEK/JMY/ACTR3B/FER/SEMA5A/DMTN/ACTR3/LMOD3/SCIN/PREX1/SLIT2/CCL26/ARPC4/SPTA1/SPTBN2/ARPC2/KANK3/MTOR/RHOA/PICK1/SNX9/CCR7/WAS/RHOBTB2/CCL24/BIN1/NCKAP1/FCHSD2/FMN1	84
BP	GO:1903510	mucopolysaccharide metabolic process	55/7096	112/18670	0.01061	0.06192	0.04616	HEXB/VCAN/ABCC5/CHSY1/NDST2/PIM1/CHP1/IDS/CD44/IL15/IMPAD1/SLC9A1/NFKB1/HEXA/CHST13/TGFB1/B3GNT2/ARSB/HGF/CHST2/HYAL2/B4GALT6/CSGALNACT1/GNS/IL1B/CSPG4/ST3GAL2/XYLT1/CHST11/SLC35D1/B3GALT6/GLCE/CHST5/IDUA/PDGFB/CHST14/XYLT2/GUSB/NDST1/CSGALNACT2/SPOCK2/B4GALT5/HYAL3/BCAN/AP2A1/CEMIP/B3GNT4/ST3GAL1/STAB2/CHST12/LYVE1/B4GALT1/SLC35D2/ITIH3/CHST7	55
BP	GO:0140014	mitotic nuclear division	119/7096	264/18670	0.0107	0.06237	0.0465	IGF1/KLHDC8B/DUSP1/MAD2L2/NUP62/RAB11A/FLNA/DYNC1LI1/RGCC/SPDL1/RAN/LRP5/CHMP4B/PSRC1/KIF3B/TGFB1/SMC5/UBE2S/SEH1L/PDS5A/INSR/CENPE/NAA10/UBXN2B/KLHL22/CDK5RAP2/SIRT7/IL1B/DSCC1/NSMCE2/TOM1L1/NSFL1C/CDKN1C/PHIP/KIF4A/SPAG5/TOM1L2/BMP7/MIS12/KIF2A/CTDP1/PDGFB/CDC23/RCC1/ESPL1/ZNF207/CENPC/LCMT1/SMC2/ATM/ANAPC5/CHAMP1/NCAPD3/BUB3/SPHK1/PHF23/AKAP8/SPICE1/BCCIP/USP16/NDC80/PPP2R2D/BMP4/CHMP2A/CDKN1B/KIF20B/MAD2L1BP/DSN1/IL1A/NDEL1/NUF2/GEN1/NUSAP1/INCENP/ZW10/CHMP1A/VPS4B/UBE2C/PRMT5/CENPK/TUBG2/NFE2L1/CDC26/CLASP2/RIOK2/DLGAP5/KIF2C/SMC3/KATNB1/RPL24/ANAPC4/MTBP/DIS3L2/MKI67/CDC27/CDC20/PIN1/PCID2/RB1/STAG1/CUL9/MISP/AURKAIP1/RHOA/AURKA/ANAPC11/IK/KPNB1/MSTO1/CHMP1B/CCDC8/RRS1/CEP85/KIF14/BOD1/AAAS/PRC1/WRAP73/L3MBTL1	119
BP	GO:0046330	positive regulation of JNK cascade	67/7096	140/18670	0.01075	0.06261	0.04668	NOD2/WNT5A/ZNF622/SH3RF1/DVL2/TNF/ERCC6/ZEB2/MAP3K4/SLAMF1/TAOK3/GADD45B/PAK1/MAP4K5/PTK2B/ROR2/TRAF6/NCF1/TLR4/TPD52L1/HRAS/IL1B/AGER/MAP3K12/RASGRP1/SDCBP/MDFIC/HMGB1/TNFRSF11A/IL1RN/MFHAS1/DUSP19/MAP4K2/EDAR/MAP3K6/MAP4K1/MLKL/MAP3K11/SH3RF3/FZD5/BIRC7/MAP3K5/PLCB1/MUL1/TRAF2/FZD4/MAP2K4/MAP3K13/ANKRD6/TLR3/FZD7/TRPV4/APP/ERN1/CCL19/TIRAP/TRAF4/WNT7A/CCR7/DAXX/SERPINF2/TLR6/FZD10/NRK/SASH1/IL37/MAP3K9	67
BP	GO:0030900	forebrain development	167/7096	381/18670	0.01079	0.06277	0.0468	NRGN/SLC8A1/ITGAM/RTN4R/FYN/ATP2B4/TRA2B/SUN2/NR4A2/SKI/RBPJ/WNT5A/TSC1/SRD5A1/TCTN1/FLNA/MBOAT7/BCL2A1/ATF5/ALK/SLC7A11/EZH2/EPHB2/EXT1/METTL14/BTBD3/KRAS/GSK3B/ZEB2/SECISBP2/ZSWIM6/BTG2/CXCL12/ANXA3/NOTCH3/AXL/CSNK2A2/LRP8/SIN3A/DNAJB1/HIF1A/RAPGEF2/PHACTR1/PCM1/ARL13B/SRF/METTL3/NRG1/XRN2/FBXO45/DPCD/HTRA2/EIF2B5/BMP2/CDK5/CASP3/PAFAH1B1/SRGAP2C/OPHN1/RAB3GAP1/SATB2/NUMB/P2RY12/LRP1/CREB1/BBS2/CRK/TYROBP/MKKS/LRRK2/PPARGC1A/ASPM/TSKU/ARX/ETS1/BBS4/DIXDC1/SYNE2/GDPD5/SRGAP2/AKNA/MFSD2A/DCLK2/BMPR1A/NRP1/DISC1/HOOK3/TRAPPC9/ATIC/BMP4/XRCC1/KDM2B/BAX/NRP2/ID2/NME1/TOP2B/PEX13/NDEL1/INHBA/DAB1/RTN4RL1/ZDHHC16/SEMA5A/BCAN/UQCRQ/LPAR1/HES1/KDM6B/CDK5R2/PLCB1/EGFR/DCT/BCL11B/SLIT2/WNT1/KAT2A/PSEN1/CHRNB2/YWHAE/RTN4RL2/BAD/HTR5A/NUMBL/PLXNA3/NR4A3/ATP7A/KIF5B/TMEM14B/EIF2B3/GNG12/CNP/PHLPP2/WNT2B/MSX1/NR2E1/PITX1/RELN/CSF1R/CEP120/RHOA/TYRO3/APP/GHRH/RTN4/C21orf91/EFNA2/PAX5/EFHC1/EZH1/LMX1A/FGF13/WNT7A/SLC8A3/OTP/AGTPBP1/SMO/SHANK3/LHX6/TWSG1/PGAP1/AVPR2/KIF14/NTRK2/POU3F1/CCKAR/ZNF335	167
BP	GO:0031396	regulation of protein ubiquitination	94/7096	204/18670	0.01086	0.06313	0.04707	NOD2/FYN/BCL10/PINK1/MAD2L2/CHP1/SMAD7/TNFAIP3/ARRDC4/BIRC2/FBXW7/RNF111/PER2/UBE2N/SKP2/PLAA/DCUN1D1/TICAM1/NMI/UBE3A/ARRDC3/GTPBP4/ARRB1/WFS1/UBE2S/FEM1B/RASSF5/PTTG1IP/TRAF6/PTPN22/HSPA5/CDK5/ABL1/GCLC/UBR5/ISG15/CDK9/LRRK2/MYCBP2/GLMN/HSPBP1/PRR7/USP4/DTX3L/SPHK1/PHF23/DCUN1D5/IVNS1ABP/AIMP2/BIRC3/ADRB2/DERL1/TSPYL5/TBC1D7/PEF1/KLHL40/UBE2C/BIRC7/STUB1/DNM1L/RNF20/FBXO4/COMMD1/BRCA1/SPOPL/BAG2/PSEN1/FANCM/MTBP/DCUN1D3/UBXN1/OGT/CDC20/DNAJA1/GNL3L/MASTL/PIN1/HSP90AB1/DCUN1D4/FOXF2/MTOR/TOPORS/SOX4/BAG5/MALT1/XIAP/PAXIP1/CHFR/DAXX/RASD2/AVPR2/SIAH2/MAPK9/SASH1	94
BP	GO:0006475	internal protein amino acid acetylation	78/7096	166/18670	0.01095	0.06359	0.04741	SPI1/POR/BAZ1A/DR1/LDB1/MORF4L2/HAT1/SUPT7L/KAT2B/MRGBP/TRIM16/TGFB1/SIN3A/ZNF451/JADE3/ARRB1/NCOA3/PCGF2/RUVBL2/RUVBL1/EPC2/MBIP/MSL3/NAA10/MBD3/KAT7/YEATS4/SETD5/TAF5L/IL1B/KAT8/TAF12/CRTC2/SIRT1/NAA40/BRD8/TAF5/PPARGC1A/FLCN/MCRS1/MUC1/KAT5/ELP3/BRPF1/NOC2L/DPF2/CTCF/RSF1/EHHADH/PHF20/ZMPSTE24/TAF6L/BRCA1/ING3/KANSL1L/CLOCK/EPC1/KAT2A/PHF10/CPA4/TAF9B/EID1/OGT/MCM3AP/ING4/SET/JADE1/USP22/SNCA/MSL1/POLE4/TADA3/PAXIP1/ACTL6A/KAT6B/WDR5/TAF7/NAA60	78
BP	GO:0000737	DNA catabolic process, endonucleolytic	20/7096	34/18670	0.011	0.06366	0.04746	AIFM1/DNASE2B/SETMAR/CASP3/NMNAT1/DFFA/HMGB1/DNASE1/IL6/DICER1/BAX/HMGB2/ST20/DNASE1L2/KPNA1/REXO4/KPNB1/ENDOG/DNASE2/MIR146A	20
BP	GO:0009164	nucleoside catabolic process	20/7096	34/18670	0.011	0.06366	0.04746	TYMP/PNP/UPP1/AHCY/HDDC3/NT5C/CDADC1/DPYD/APOBEC3G/APOBEC3C/APOBEC2/DERA/ADA/APOBEC3B/CDA/NT5C3A/ENPP4/NT5M/UPP2/ADAL	20
BP	GO:0042558	pteridine-containing compound metabolic process	20/7096	34/18670	0.011	0.06366	0.04746	GCH1/MTHFD2/MTR/FOLR2/PCBD1/MTRR/QDPR/PTS/SPR/SHMT2/ATIC/SLC46A1/TYMS/SHMT1/DHFR/FPGS/ALDH1L1/PCBD2/SLC25A32/PIPOX	20
BP	GO:0060828	regulation of canonical Wnt signaling pathway	128/7096	286/18670	0.011	0.06366	0.04746	MAD2L2/RBPJ/WNT5A/PSMB9/JRK/ZBED3/KLHL12/PSMB8/WLS/CSNK1G2/LGR4/EGR1/PSMA5/DVL2/PSMD11/GPRC5B/NFKB1/APOE/GSK3B/PSME1/PTPRO/GNAQ/PSMB10/IGFBP4/TLE1/PSMA1/MCC/PSMA4/CSNK1D/ROR2/LATS1/RUVBL2/RUVBL1/FUZ/FZD9/BMP2/TLE4/PSMB1/GID8/EMD/PSMC4/UBR5/FRAT1/RNF146/SFRP4/PSMD13/IGFBP2/PSMB3/TRPM4/TMEM170B/CYLD/LRRK2/MESP1/ASPM/SULF2/DDX3X/PSMB5/PSMD6/CSNK1A1/EDA/CSNK1E/PSMC3/TMEM64/NPHP4/NRARP/PSME3/ZNF703/PSMC6/TLE6/KANK1/TMEM88/CSNK1G3/ZBED2/GSKIP/NKD2/MKS1/SEMA5A/FZD1/DKK2/PPP1CA/EGFR/CCNY/DVL1/PSEN1/TCF7L2/LGR5/CTHRC1/IFT20/PSMC1/PSMD8/PSMA2/ARNTL/LATS2/PIN1/ANKRD6/FZD7/JADE1/PFDN5/TBL1X/PSMC5/LGR6/PSMC2/PSMB2/PSMD4/VCP/PRDM15/CDH3/RBX1/SOX4/SDHAF2/KREMEN1/XIAP/LRP4/PSMD1/SFRP5/AMER3/UBE2B/WNT10B/PSMB4/CSNK1G1/GREM1/DAAM2/PSMD9/PSMD3/SIAH2/FOXO3/WNK2/SOX7	128
BP	GO:0002448	mast cell mediated immunity	27/7096	49/18670	0.01106	0.0639	0.04764	RAC2/SERPINB9/LYN/IL4R/HMOX1/C12orf4/STXBP1/LAT2/STXBP2/FGR/RASGRP1/S100A13/PLA2G3/ADORA2B/PIK3CD/UNC13D/CD300A/LGALS9/FER/RABGEF1/IL13RA2/CD84/NR4A3/PIK3CG/SNX4/FOXF1/LAT	27
BP	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	27/7096	49/18670	0.01106	0.0639	0.04764	SRPX/PEA15/SKIL/BCL10/PMAIP1/PTPRC/PDIA3/CTNNA1/HYAL2/HTRA2/TNFRSF12A/TNFSF10/PAK2/DEDD2/PML/RBCK1/G0S2/CYLD/WWOX/INHBA/PPP1CA/PPP2R1B/FADD/TRAF2/RET/ZSWIM2/BMPR1B	27
BP	GO:0051893	regulation of focal adhesion assembly	32/7096	60/18670	0.01114	0.06421	0.04787	S100A10/TSC1/LDB1/SLC9A1/DUSP3/PEAK1/VEGFA/ABL1/LRP1/PPM1F/SLK/RAC1/PTK2/ARHGAP6/LIMCH1/NRP1/WDPCP/BCAS3/MMP14/DMTN/CORO1C/CLASP2/RCC2/HRG/MAP4K4/RHOA/LIMS1/ITGB1BP1/ROCK2/MACF1/PTPRJ/FMN1	32
BP	GO:0090109	regulation of cell-substrate junction assembly	32/7096	60/18670	0.01114	0.06421	0.04787	S100A10/TSC1/LDB1/SLC9A1/DUSP3/PEAK1/VEGFA/ABL1/LRP1/PPM1F/SLK/RAC1/PTK2/ARHGAP6/LIMCH1/NRP1/WDPCP/BCAS3/MMP14/DMTN/CORO1C/CLASP2/RCC2/HRG/MAP4K4/RHOA/LIMS1/ITGB1BP1/ROCK2/MACF1/PTPRJ/FMN1	32
BP	GO:0009749	response to glucose	91/7096	197/18670	0.01114	0.06421	0.04787	SLC8A1/TRA2B/LDHA/ACVR2B/ATG7/GCLM/TXNIP/PPARD/SMAD2/ENY2/EGR1/HMGCR/LRP5/TGFB1/PPP3CB/SIN3A/AACS/UNC13B/FIS1/ARRB1/HIF1A/PIM3/PTK2B/PCK2/SRF/EIF2B5/IGF1R/CASP3/GCLC/AGER/C2CD2L/RAP1A/MPC2/LRP1/RAF1/TRPM4/RAC1/IRS2/ZNF236/PPARGC1A/KLF7/SRI/OXCT1/POLG/KHK/GPR27/CDKN1B/NME1/RMI1/PRKACA/LGALS1/CTSV/PDX1/CYBA/PTPRN2/PFKFB2/HMGN3/CMA1/GIPR/PRKAA1/TCF7L2/COL4A3/BAD/PLA2G6/EIF2B1/HNF1B/KIF5B/EIF2B3/MEN1/WDR35/ZBTB20/NDUFAF2/MAP4K4/RHOA/ERN1/SLC9B2/SOX4/SIDT2/GCG/EIF2B2/PFKL/ENDOG/GJA1/NR1H4/STXBP4/SESN2/UCN3/FOXO3/GHRL/MIR146A/PHPT1	91
BP	GO:0007229	integrin-mediated signaling pathway	51/7096	103/18670	0.01116	0.06426	0.0479	ITGAM/BST1/ITGA5/ITGB7/HCK/ITGB5/NEDD9/FLNA/ZNF304/ITGAD/TLN1/CTNNA1/PTK2B/ITGAL/ADAM15/CD63/TSPAN32/ITGA4/ITGA7/FGR/ABL1/ITGA11/ISG15/TYROBP/ITGAE/PTK2/MYH9/ZYX/EMP2/NRP1/CD47/TIMP1/TEC/MADCAM1/ITGA2/PLEK/ITGA3/DMTN/VAV1/RCC2/CDH17/ADAM9/APOA1/PRAM1/ITGA8/PHACTR4/LIMS1/ITGB1BP1/PLP1/LAT/ADAM11	51
BP	GO:0035303	regulation of dephosphorylation	96/7096	209/18670	0.01123	0.06456	0.04813	LILRB2/PINK1/TSC1/CAMTA1/PPP1R15A/CHP1/MGAT5/WDR81/JAK2/PTPRC/SHOC2/TNF/GSK3B/CABIN1/PPP4R2/TGFB1/PHACTR2/PPP2R3A/PHACTR1/PPP1R16A/PPP1R26/SWAP70/PPP6R1/PRKCD/SPOCD1/PPP1R14A/ELFN1/PPP1R37/BMP2/RCAN3/PPP1R2/SFI1/SLC39A10/PPP1R14B/CNST/SEMA4D/SYMPK/PPP1R15B/PPP1R16B/MFHAS1/CDH5/PPP2R5C/CD2BP2/ANKLE2/LMTK3/ZFYVE1/GNAI2/PPP2R2D/MTMR4/BOD1L1/PPP2R2B/INPP5K/ELFN2/PPP1R3B/RCAN1/ITGA2/PPP2R3C/MTMR2/CD300A/PPP4R1/PLEK/PPP1R36/ZCCHC9/PPP1R7/MYOZ1/NSMF/SPRED1/PPP2R1B/EIF2AK2/PPP1R11/HSP90B1/MTMR3/YWHAE/SYTL2/IGBP1/LMTK2/IFNG/CHP2/MTMR9/MASTL/PIN1/B3GAT3/SMPD1/PPP1R14D/HSP90AB1/PPP2R5B/PHACTR4/SET/CD33/CDCA2/MTOR/ROCK2/CCDC8/BOD1/PPP2R2C/MEF2C	96
BP	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	44/7096	87/18670	0.01123	0.06456	0.04813	IGF1/FYN/PTPN6/LYN/FLT1/PPARD/PRR5/JAK2/TNF/GAB1/HCLS1/UBE3A/HGF/LEP/INSR/NCF1/FLT3/PDGFC/EPOR/FGR/IGF1R/CAT/CCL5/SEMA4D/SIRT1/IRS2/PDGFB/PTK2/NEDD4/PIK3CD/OSM/UNC5B/PDGFA/F2R/SERPINA12/IL18/MAZ/FSHR/PIK3CG/RELN/ERBB3/PDGFD/NTRK2/PIK3CB	44
BP	GO:0043901	negative regulation of multi-organism process	80/7096	171/18670	0.01146	0.06562	0.04892	IGF1/TRIM32/ZFP36/ARG2/FCN1/PLSCR1/TNFAIP3/FGL2/STAT1/LILRA2/OASL/IFITM2/TNF/IFITM1/TRIM13/IFITM3/MORC2/ISG20/PTX3/MAPKBP1/TRIM26/TFAP4/OAS3/ARHGDIB/CACTIN/RSAD2/CCL5/SRPK2/PML/ISG15/TRIM11/APOBEC3G/MAVS/APOBEC3C/IFIT5/ILF3/BANF1/ZC3HAV1/NPLOC4/SEC14L1/TRIM21/TARBP2/CCL8/TNIP1/INPP5K/TIMP1/CCNK/SIGLEC11/MX1/SETDB1/RNASEL/HTRA1/PCBP2/HPGDS/IFIT1/SRPK1/ADA/CALR/EIF2AK2/C1QBP/MUL1/GPATCH3/MID2/ANXA2P2/RIOK3/SIGIRR/HAVCR2/TRIM15/NLRX1/LACRT/TRAF3IP1/TRIM6/EIF2AK4/ANXA2/TSPAN6/CCL4/TARDBP/FAM3A/APCS/BTBD17	80
BP	GO:0006739	NADP metabolic process	19/7096	32/18670	0.01146	0.06562	0.04892	TALDO1/KCNAB2/ME1/PGAM1/RPE/TKT/RPIA/NADK2/IDH1/G6PD/IDH2/PGM2/DERA/PGD/ME2/FMO2/NNT/PGLS/RBKS	19
BP	GO:0048741	skeletal muscle fiber development	19/7096	32/18670	0.01146	0.06562	0.04892	SKI/KLHL41/RYR1/HOMER1/MYOG/BCL2/HDAC4/KLHL40/LMOD3/BIN3/SHOX2/DNER/GPX1/P2RX2/WNT10B/ACTA1/SMO/KEL/MYF6	19
BP	GO:1905508	protein localization to microtubule organizing center	19/7096	32/18670	0.01146	0.06562	0.04892	NUP62/SNX10/GSK3B/GOLGB1/PCM1/CSNK1D/CEP131/UBXN2B/KIAA0753/NSFL1C/SPAG5/BICD1/BBS4/DISC1/HOOK3/DCTN2/CEP83/AURKA/C2CD3	19
BP	GO:0034470	ncRNA processing	168/7096	384/18670	0.01147	0.06562	0.04892	TRMT6/SEPHS2/DDX21/LYAR/DPH3/ALKBH1/FTSJ1/SMAD2/TPRKB/OSGEPL1/FAM98B/AGO2/ELP4/RPP38/TRMT5/TRMT1/TSR1/GTPBP4/WDR46/UTP14A/TYW3/ISG20/INTS5/ISG20L2/METTL3/XRN2/NAF1/INTS7/DDX49/TFB1M/BCDIN3D/DUS2/TOE1/KRI1/HNRNPA2B1/LCMT2/TRMT112/KRR1/RNF113A/INTS9/TRMT61B/RPP25/RPUSD2/ELAC1/NSUN2/SIRT1/ABT1/USB1/RPS24/MRPL44/TRMT1L/RPP14/PUS1/TP53RK/CLP1/INTS8/WDR74/NOLC1/MRTO4/NAT10/OSGEP/DDX24/RPS21/THUMPD1/DICER1/RPS9/FBL/RRP7A/RPS19/SUV39H1/NHP2/LAS1L/METTL1/UTP15/TARBP2/ELP3/METTL8/EXOSC2/HSD17B10/GAR1/FTSJ3/RPF2/FDXACB1/AGO1/DDX1/QTRT1/RNASEL/DIMT1/ZCCHC4/WDR4/ALKBH8/WDR36/INTS3/EXOSC7/RCL1/THUMPD2/MOCS3/TRMT11/WDR75/METTL15/DCAF13/INTS2/NOL8/RRP15/THUMPD3/RIOK2/NOL10/SART1/SSB/RIOK3/ERI3/RPP40/ELP2/MPHOSPH6/TEX10/MRM1/IMP4/RPS16/WBP11/EXOSC9/NOC4L/DDX18/MTFMT/EXOSC3/DDX27/RPL7L1/FAM207A/RPPH1/FBLL1/NSUN5P1/POP7/REXO4/TSR2/DROSHA/ADAT2/MDN1/MTO1/DDX54/DDX10/C2orf49/EXOSC6/CPSF1/DUS1L/TRMT10C/ADAR/PUS7/GTPBP3/EXOSC8/MRPS9/SRRT/INTS4/ZNHIT6/NUDT16/NSUN6/NOP10/C1D/UTP3/RRS1/AARS2/INTS6/ESF1/PA2G4/POLR3K/ADAT1/EXOSC5/DDX52/MRPL1/RPL10A	168
BP	GO:0043666	regulation of phosphoprotein phosphatase activity	57/7096	117/18670	0.01148	0.06562	0.04892	TSC1/PPP1R15A/MGAT5/JAK2/PTPRC/SHOC2/TNF/GSK3B/CABIN1/PPP4R2/PHACTR2/PPP2R3A/PHACTR1/PPP1R16A/PPP1R26/PPP6R1/PPP1R14A/ELFN1/PPP1R37/RCAN3/PPP1R2/SLC39A10/PPP1R14B/PPP1R15B/PPP1R16B/PPP2R5C/ANKLE2/GNAI2/PPP2R2D/BOD1L1/PPP2R2B/ELFN2/PPP1R3B/RCAN1/CD300A/PPP4R1/PPP1R36/PPP1R7/MYOZ1/PPP2R1B/EIF2AK2/PPP1R11/HSP90B1/IGBP1/LMTK2/MASTL/B3GAT3/PPP1R14D/HSP90AB1/PPP2R5B/PHACTR4/SET/CD33/MTOR/ROCK2/BOD1/PPP2R2C	57
BP	GO:0030183	B cell differentiation	63/7096	131/18670	0.01153	0.06581	0.04906	PTPN6/DLL1/KLF6/NOTCH2/RBPJ/PTPN2/BCL6/CEBPG/LFNG/PTPRC/DOCK10/ZBTB7A/POU2F2/PTK2B/ZBTB1/TCIRG1/ITGA4/FLT3/FZD9/GON4L/ABL1/PLCG2/ITM2A/TPD52/IL7/BLNK/CYLD/ATM/LYL1/FNIP1/BCL2/BAX/HDAC4/ID2/MS4A1/CLCF1/LGALS1/IFNK/CR2/PPP2R3C/INHBA/MMP14/DNAJB9/ADA/LRRC8A/ITFG2/ADAM17/DOCK11/CDH17/NFAM1/BAD/ZFP36L2/DCLRE1C/PLCL2/PCID2/INHA/HDAC5/GPR183/IKZF3/MALT1/BAK1/SLAMF8/PTPRJ	63
BP	GO:0009746	response to hexose	93/7096	202/18670	0.01154	0.06581	0.04906	SLC8A1/NAMPT/TRA2B/LDHA/ACVR2B/ATG7/GCLM/TXNIP/PTGS2/PPARD/SMAD2/ENY2/EGR1/HMGCR/LRP5/TGFB1/PPP3CB/SIN3A/AACS/UNC13B/FIS1/ARRB1/HIF1A/PIM3/PTK2B/PCK2/SRF/EIF2B5/IGF1R/CASP3/GCLC/AGER/C2CD2L/RAP1A/MPC2/LRP1/RAF1/TRPM4/RAC1/IRS2/ZNF236/PPARGC1A/KLF7/SRI/OXCT1/POLG/KHK/GPR27/CDKN1B/NME1/RMI1/PRKACA/LGALS1/CTSV/PDX1/CYBA/PTPRN2/PFKFB2/HMGN3/CMA1/GIPR/PRKAA1/TCF7L2/COL4A3/BAD/PLA2G6/EIF2B1/HNF1B/KIF5B/EIF2B3/MEN1/WDR35/ZBTB20/NDUFAF2/MAP4K4/RHOA/ERN1/SLC9B2/SOX4/SIDT2/GCG/EIF2B2/PFKL/ENDOG/GJA1/NR1H4/STXBP4/SESN2/UCN3/FOXO3/GHRL/MIR146A/PHPT1	93
BP	GO:0051048	negative regulation of secretion	108/7096	238/18670	0.01154	0.06581	0.04906	CRHBP/CCR2/FN1/EZR/PTGER4/IL27RA/ANXA1/IL1R2/RHBDF2/GBP1/ARG2/RAP1B/SYT11/ERP29/TMBIM6/DPH3/LILRA5/NLRP3/HADH/TNFAIP3/BANK1/SIRT4/LGR4/ENY2/NLRP12/RGCC/FAM3D/TNF/CD74/HMOX1/TNFRSF21/APOE/HMGCR/LILRB1/CD22/PIM3/ENHO/LEP/PNKD/SERPINB1/HLA-F/NRG1/MAPKBP1/PTPN22/ABR/VAMP3/RSAD2/IL1B/RAP1A/PML/P2RY12/TIFAB/RAB33B/KALRN/CD200R1/KLF7/IDH2/BCR/GNAI2/NR1H3/FFAR4/SYTL4/OSM/INHBA/CD300A/LGALS9/VPS4B/RABGEF1/BTN2A2/CPTP/ADA/F2R/PPP1R11/NMB/MAOB/TLR8/FMR1/SRGN/IL13RA2/APOA1/TNFRSF4/FRMD4A/CD84/NPVF/CD34/IL1RAPL1/INHA/STXBP3/SYT4/NDUFAF2/MAP4K4/C5AR2/SNCA/CX3CL1/FOXF1/SPX/PFKL/FGF23/NR1H4/ERBB3/TLR6/PSMD9/C1QTNF3/P2RY1/AVPR2/TACR2/GHRL/RHBDF1	108
BP	GO:0051495	positive regulation of cytoskeleton organization	103/7096	226/18670	0.01159	0.06604	0.04923	S100A10/CDC42EP4/VASP/ARF6/FHOD1/TSC1/NUP62/SORBS3/HCK/RHOBTB1/FLNA/RHOC/RGCC/P2RX7/SPIRE1/IQGAP2/ARHGEF10L/ACTR2/HCLS1/EVL/PSRC1/PFN1/CDC42EP2/PAK1/CLIP1/PTK2B/CFL2/SWAP70/GMFG/CORO1A/BAIAP2/UBXN2B/NCK1/CDK5/HRAS/ABL1/FCHSD1/CDK5RAP2/ARPC1A/NSFL1C/MAPRE1/SPAG5/PPM1F/RAC1/ARPIN/ARPC1B/CDC42EP3/CYFIP1/MYO1C/CORO1B/LIMCH1/ARF1/ARPC5L/NRP1/TPM1/BCAS3/CD47/CDKN1B/CFL1/GRB2/PLEK/JMY/ACTR3B/VPS4B/FER/SEMA5A/LPAR1/ACTR3/PXN/LMOD3/GPSM2/CAV3/SCIN/CCL26/APOA1/KATNB1/ARPC4/TGFB3/PLXNA3/SLAIN2/SYNPO2L/ARPC2/CEP120/MTOR/NAV3/RHOA/TRPV4/PICK1/CX3CL1/ITGB1BP1/SNX9/MET/CCR7/WAS/ROCK2/RHOBTB2/CCL24/SERPINF2/BIN1/NCKAP1/FCHSD2/SYNPO/FMN1	103
BP	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient	10/7096	14/18670	0.0117	0.0661	0.04928	ATP1A1/ATP4A/ATP1B2/ATP1B3/BAX/ATP1B1/FXYD2/BAK1/ATP1A2/ATP12A	10
BP	GO:0010935	regulation of macrophage cytokine production	10/7096	14/18670	0.0117	0.0661	0.04928	WNT5A/IRAK3/CD74/GPRC5B/LILRB1/TGFB1/CD36/TLR4/HLA-G/TGFB3	10
BP	GO:0045064	T-helper 2 cell differentiation	10/7096	14/18670	0.0117	0.0661	0.04928	ANXA1/BCL6/NLRP3/IL4R/BATF/SOCS5/HLX/IL18/TNFSF4/PRKCZ	10
BP	GO:0045591	positive regulation of regulatory T cell differentiation	10/7096	14/18670	0.0117	0.0661	0.04928	LILRB2/BCL6/DUSP10/TGFB1/LILRB4/HLA-G/LGALS9/BTN2A2/SOCS1/IFNG	10
BP	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade	10/7096	14/18670	0.0117	0.0661	0.04928	ATP2B4/CHP1/GSK3B/DYRK2/MAPK7/HOMER3/RCAN1/MYOZ1/FHL2/MTOR	10
BP	GO:0072567	chemokine (C-X-C motif) ligand 2 production	10/7096	14/18670	0.0117	0.0661	0.04928	KLF4/MBP/MIF/TNF/CD74/LRP1/MCOLN2/MAP2K5/FOXP1/TIRAP	10
BP	GO:0106057	negative regulation of calcineurin-mediated signaling	10/7096	14/18670	0.0117	0.0661	0.04928	ATP2B4/CHP1/GSK3B/DYRK2/MAPK7/HOMER3/RCAN1/MYOZ1/FHL2/MTOR	10
BP	GO:2001044	regulation of integrin-mediated signaling pathway	10/7096	14/18670	0.0117	0.0661	0.04928	BST1/FLNA/CTNNA1/CD63/EMP2/TIMP1/DMTN/PHACTR4/LIMS1/ITGB1BP1	10
BP	GO:0050770	regulation of axonogenesis	85/7096	183/18670	0.0117	0.0661	0.04928	RTN4R/FN1/SIPA1L1/DPYSL2/SKIL/WNT5A/SEMA4B/SPP1/RAB11A/MAP2K1/ULK2/EPHB2/ARHGDIA/IFRD1/APOE/GSK3B/ZEB2/ZSWIM6/CXCL12/PTPRO/PLXNB2/TWF2/SIN3A/PAK1/MEGF8/PLXNC1/SRF/SEMA4A/VEGFA/CDK5/TNFRSF12A/TRAK2/ABL1/PAFAH1B1/GDI1/SEMA4C/SEMA4D/LRP1/DCC/CYFIP1/MYCBP2/PTK2/SEMA6B/PLXNA1/NRP1/DISC1/SEMA3B/PLXND1/DNM2/L1CAM/MARK2/LPAR3/IST1/NDEL1/SYNGAP1/DAB1/OLFM1/WDR36/SEMA5A/FSTL4/AMIGO1/SLIT2/PSEN1/SEMA5B/SHOX2/MAP3K13/RUFY3/PLXNA3/RET/TRAK1/PLXNA2/CHODL/RHOA/BRSK1/RTN4/CRABP2/FGF13/LRP4/WNT7A/KEL/MACF1/TRPV2/NTRK2/TRIM46/BMPR2	85
BP	GO:0043303	mast cell degranulation	26/7096	47/18670	0.01175	0.06623	0.04938	RAC2/LYN/IL4R/HMOX1/C12orf4/STXBP1/LAT2/STXBP2/FGR/RASGRP1/S100A13/PLA2G3/ADORA2B/PIK3CD/UNC13D/CD300A/LGALS9/FER/RABGEF1/IL13RA2/CD84/NR4A3/PIK3CG/SNX4/FOXF1/LAT	26
BP	GO:0061614	pri-miRNA transcription by RNA polymerase II	26/7096	47/18670	0.01175	0.06623	0.04938	KLF4/FOS/SPI1/STAT3/PPARD/RELA/TGFB1/NFATC3/HIF1A/SRF/LILRB4/BMP2/PDGFB/ETS1/BMPR1A/BMP4/HDAC4/YY1/KLF5/SREBF2/PPARA/FOSL1/TERT/GNL3/WT1/APLN	26
BP	GO:1901659	glycosyl compound biosynthetic process	26/7096	47/18670	0.01175	0.06623	0.04938	TYMP/UPP1/GMPS/TYW3/ADK/GUK1/IMPDH1/CTPS2/LCMT2/CMPK1/TK1/PRTFDC1/NME3/MTAP/NME4/NME1/ADA/DCK/UCK1/TK2/CTPS1/CAD/CDA/UCKL1/UPP2/ADAL	26
BP	GO:0035306	positive regulation of dephosphorylation	31/7096	58/18670	0.0119	0.06696	0.04992	LILRB2/PINK1/CAMTA1/PPP1R15A/JAK2/PTPRC/TGFB1/PRKCD/BMP2/SLC39A10/SYMPK/PPP1R15B/PPP1R16B/CDH5/ANKLE2/ITGA2/CD300A/PLEK/PPP1R7/NSMF/IFNG/CHP2/MTMR9/PIN1/SMPD1/PPP1R14D/HSP90AB1/CD33/CDCA2/MTOR/MEF2C	31
BP	GO:0032728	positive regulation of interferon-beta production	18/7096	30/18670	0.01191	0.06696	0.04992	TLR2/IRF7/IRF1/FLOT1/TICAM1/TLR4/DDX58/DHX9/MAVS/DDX3X/IFIH1/HMGB2/TLR8/RIOK3/TLR3/ZBTB20/POLR3F/RNF135	18
BP	GO:0070979	protein K11-linked ubiquitination	18/7096	30/18670	0.01191	0.06696	0.04992	UBE2S/UBE2D3/UBE2D2/UBE2W/UBE2A/CDC23/ANAPC5/UBE2E2/UBE2D4/ANAPC7/UBE2C/CDC26/ANAPC4/CDC27/RNF4/ANAPC11/ANAPC13/UBE2B	18
BP	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	50/7096	101/18670	0.01195	0.06708	0.05001	CTSF/CTSD/KLC1/AP1B1/DYNC1LI1/CTSS/LGMN/CD74/KIF3B/OSBPL1A/KIFAP3/SAR1B/CAPZA2/DYNLL2/TRAF6/CENPE/HLA-DPB1/HLA-DPA1/CAPZA1/KIF4A/HLA-DMB/HLA-DOB/KIF2A/HLA-DRA/AP1M2/HLA-DMA/ARF1/AP2A2/DNM2/DCTN2/LAG3/AP2S1/CTSV/CTSE/CANX/AP2A1/AP1S3/AP1G1/HLA-DQB2/KIF2C/TREM2/AP1M1/SPTBN2/DYNC1LI2/KLC2/AP2M1/DCTN6/DCTN5/SEC24A/HLA-DOA	50
BP	GO:1903008	organelle disassembly	50/7096	101/18670	0.01195	0.06708	0.05001	ATG7/PINK1/ATG3/RNF41/KLC1/CISD2/FBXW7/ATG14/SQSTM1/CTSK/KIF9/CSNK2A2/CDC37/FIS1/HIF1A/MAP1LC3A/MTIF2/EIF2D/HTRA2/TEX264/ATG13/WIPI1/PPARGC1A/MAP1LC3C/STX5/MCTS1/ATG9A/PLK3/VPS13D/MARK2/GFM2/ATG2B/WDR45B/USP30/SREBF2/FZD5/DNM1L/VDAC1/DYRK3/MUL1/VRK1/MTIF3/KIF5B/GABARAPL1/CLEC16A/OPTN/VCP/ATG12/FUNDC1/MRRF	50
BP	GO:0008203	cholesterol metabolic process	71/7096	150/18670	0.01203	0.06745	0.05028	POR/CYP27A1/SOD1/NFYC/GPAM/NPC2/PPARD/APOC1/SCARB1/SQLE/SOAT1/CETP/RAN/APOE/HMGCR/LIMA1/HDLBP/CLN8/OSBPL1A/HMGCS1/SCD/LEP/ERLIN1/CNBP/CEBPA/CAT/ACLY/ABCA1/LDLR/LMF1/ERLIN2/FDPS/ACACB/APOBR/DGAT2/G6PD/FGF1/ARV1/APOL1/GNB3/TM7SF2/APOA5/MSMO1/IDI1/LCAT/RXRA/SCAP/ABCG1/APOL2/SC5D/CH25H/CLN6/SREBF2/ACADVL/CYB5R3/FDX1/NFE2L1/SERPINA12/INSIG1/ACAA2/PRKAA1/APOA1/SMPD1/MBTPS2/APP/ELOVL6/MBTPS1/KPNB1/CYP46A1/NR1H4/SNX17	71
BP	GO:0043543	protein acylation	112/7096	248/18670	0.01213	0.06797	0.05067	SPI1/POR/BAZ1A/ZDHHC20/NMT2/DR1/ABHD17C/LDB1/MORF4L2/HAT1/NUPR1/GSK3B/SUPT7L/KAT2B/MRGBP/TRIM16/ZDHHC9/TGFB1/SIN3A/ZNF451/NATD1/JADE3/ARRB1/NAA20/NCOA3/PCGF2/RUVBL2/RUVBL1/EPC2/MBIP/MSL3/NAA10/MBD3/KAT7/YEATS4/SETD5/TAF5L/IL1B/DSCC1/ZDHHC6/KAT8/TAF12/OGDH/CRTC2/SIRT1/NAA40/BRD8/ZDHHC5/TAF5/PPARGC1A/FLCN/MCRS1/MIR34A/MUC1/SPHK1/HDAC2/KAT5/ELP3/BRPF1/NOC2L/HHAT/DPF2/CTCF/RSF1/CDYL/EHHADH/PHF20/ZDHHC16/ZMPSTE24/BLOC1S1/TAF6L/NAA16/BRCA1/ING3/FAM161A/ZDHHC14/HINT2/KANSL1L/CLOCK/EPC1/KAT2A/PRKAA1/PHF10/ZDHHC2/CPA4/TAF9B/ZDHHC18/EID1/ARNTL/OGT/MCM3AP/LACRT/ING4/SET/JADE1/NAA15/USP22/SNCA/CLIP3/MSL1/SOX4/ZDHHC12/POLE4/TADA3/PAXIP1/ZDHHC21/ACTL6A/KLF15/KAT6B/WDR5/TAF7/NAA60	112
BP	GO:0031345	negative regulation of cell projection organization	87/7096	188/18670	0.01215	0.068	0.0507	RTN4R/FYN/DPYSL3/ARF6/DNM3/WNT5A/DENND5A/TSC1/SEMA4B/VIM/LRIG2/SPP1/CIB1/ULK2/YWHAH/CERS2/EPHB2/ARHGDIA/IFRD1/APOE/GSK3B/PTPRO/EVL/UBE3A/DGUOK/RAPGEF2/MAP4/BCL11A/PRKCD/SEMA4A/CDK5/PLK2/TRAK2/PAFAH1B1/CTSZ/SRGAP2C/GDI1/SEMA4C/PAQR3/SEMA4D/LRP1/ARPIN/RAB29/LRRK2/DCC/PTK2/SEMA6B/HDAC2/MAK/NRP1/SEMA3B/DNM2/KANK1/LGALS1/SYNGAP1/DAB1/TBC1D7/INPP5F/RTN4RL1/SEMA5A/ITGA3/LPAR1/FSTL4/SLIT2/SPRY2/PSEN1/TCHP/MDM2/SEMA5B/RTN4RL2/RUFY3/PLXNA3/SPOCK1/HRG/NR2F1/TACSTD2/CARM1/MAP4K4/RHOA/TRPV4/RTN4/BAG5/KREMEN1/ASAP1/FGF13/LRP4/TRIM46	87
BP	GO:0030004	cellular monovalent inorganic cation homeostasis	53/7096	108/18670	0.01216	0.068	0.0507	SLC8A1/ATP6V0D2/GRN/SLC11A1/SLC9A9/ATP1A1/ATP6AP1/DMXL1/CHP1/ATP6V1C1/ATP6V0C/SLC9A1/AQP11/TCIRG1/CLCN3/ATP6V1A/ATP4A/CLN3/VPS33A/RAB20/ATP6V1G3/ATP1B2/ATP6V1B2/SLC9A8/LRRK2/RAB38/SLC9A7/ATP6V1D/ATP1B3/ROGDI/ATP6AP1L/MAFG/BCL2/ATP6V0E2/ATP1B1/CLN6/CLN5/SLC4A5/ATP6V1G2/MAPK1/SLC4A7/SLC4A1/KCNMA1/ATP6V1B1/TM9SF4/ATP1A2/SLC4A11/SLC9C2/ATP12A/SLAMF8/SLC4A3/C7/DMXL2	53
BP	GO:0043967	histone H4 acetylation	35/7096	67/18670	0.01225	0.06842	0.05101	SPI1/MORF4L2/HAT1/TRIM16/JADE3/ARRB1/RUVBL2/RUVBL1/MSL3/KAT7/YEATS4/KAT8/SIRT1/NAA40/BRD8/MCRS1/MUC1/KAT5/PHF20/ZMPSTE24/BRCA1/ING3/KANSL1L/EPC1/KAT2A/OGT/ING4/JADE1/USP22/MSL1/TADA3/ACTL6A/KAT6B/WDR5/NAA60	35
BP	GO:1901264	carbohydrate derivative transport	39/7096	76/18670	0.01226	0.06842	0.05101	SLC29A1/SLC29A3/SLC25A19/SLC37A2/NPC2/SLC25A25/SLC33A1/SCARB1/SLC37A4/PSAP/GUK1/SLC35B4/SLC35D1/SLC28A3/SLC25A5/MFSD2A/PLEKHA8/ABCG1/SLC50A1/CYBA/SLC29A2/ADA/SLC17A5/SLC35B1/SLC35A3/SLC35C1/SLC35A5/SLC17A4/RALBP1/SYTL2/SLC25A24/LBP/ABCD1/SLC35A2/GJA1/SLC35D2/GLTP/G6PC/SLC29A4	39
BP	GO:0001773	myeloid dendritic cell activation	17/7096	28/18670	0.01232	0.06842	0.05101	SPI1/RBPJ/CLEC4D/BATF3/CD2/BATF/SLAMF1/TGFB1/TRAF6/TSPAN32/FLT3LG/RELB/HMGB1/BATF2/PSEN1/DCSTAMP/HAVCR2	17
BP	GO:0002691	regulation of cellular extravasation	17/7096	28/18670	0.01232	0.06842	0.05101	CCR2/PTGER4/IL27RA/BST1/ADAM8/CXCL12/PTAFR/ITGA4/CD99/ABR/AGER/IL1R1/BCR/CD99L2/PLCB1/FADD/PDGFD	17
BP	GO:0035456	response to interferon-beta	17/7096	28/18670	0.01232	0.06842	0.05101	IRF1/MNDA/CAPN2/PLSCR1/XAF1/STAT1/IFITM2/IFITM1/IFITM3/AIM2/UBE2K/HTRA2/UBE2G2/TLR3/IFNAR2/TRIM6/PNPT1	17
BP	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway	17/7096	28/18670	0.01232	0.06842	0.05101	EZR/PTPN6/GBP1/PTPN2/LPXN/DUSP3/CD22/LILRB4/PTPN22/ELF1/MIR34A/CD300A/BTN2A2/PLCL2/UBASH3A/PTPRJ/PHPT1	17
BP	GO:0061615	glycolytic process through fructose-6-phosphate	17/7096	28/18670	0.01232	0.06842	0.05101	HK3/PGK1/PFKM/PFKP/GAPDH/PGAM1/PKM/GALK1/TPI1/ALDOC/ENO1/ALDOA/GPI/FOXK2/ENO2/ADPGK/PFKL	17
BP	GO:0061620	glycolytic process through glucose-6-phosphate	17/7096	28/18670	0.01232	0.06842	0.05101	HK3/PGK1/PFKM/PFKP/GAPDH/PGAM1/PKM/GALK1/TPI1/ALDOC/ENO1/ALDOA/GPI/FOXK2/ENO2/ADPGK/PFKL	17
BP	GO:0051052	regulation of DNA metabolic process	186/7096	429/18670	0.01238	0.06854	0.0511	KLF4/USP51/IL27RA/DUSP1/CDKN1A/SPI1/ATG7/MAD2L2/PPP2CA/PARP9/AIFM1/STAT6/RAD51AP1/BCL6/CDAN1/EYA3/CD40/CEBPG/FBXW7/MYC/KDM1B/RGCC/PTPRC/UBE2N/SLFN11/ZNF304/SPIRE1/KLHL15/S100A11/ERCC6/ERCC4/MAP3K4/GMNN/MAGEF1/ALYREF/ACTR2/PPP4C/ANXA3/IL7R/PPP4R2/TGFB1/HGF/GTPBP4/MORC2/ZNF91/ZNF830/PTK2B/PDS5A/PRKCD/PKIB/RBBP6/MBD1/UIMC1/TMEM161A/NAF1/DEK/DBF4B/MBD3/RMI2/SETMAR/HNRNPA1/USP9X/HRAS/NPM1/NMNAT1/HNRNPA2B1/WRNIP1/DNAJC2/DFFA/DSCC1/GZMA/XRCC5/PARG/UBR5/DHX9/DONSON/DCP2/PML/HMGB1/SMCHD1/NUDT16L1/SMARCAD1/SIRT1/TIPIN/RAC1/CCDC88A/IL6/PDGFB/CDK9/PPARGC1A/FLCN/NAT10/RFC3/PTGES3/OTUD4/ATM/POLH/ENPP7/DTX3L/MAPKAPK5/HDAC10/PARM1/RAD52/HNRNPC/RAD17/MLH1/XRN1/PRKD2/PCNA/DNMT3L/XRCC1/PARP3/BAX/ANKRD17/ERCC1/FUS/CLCF1/USP1/SETDB1/ST20/TIMELESS/KCNK2/HNRNPD/TICRR/PRMT5/CCT4/ZMPSTE24/KDM4D/CACYBP/FBXO4/CCT8/BRCA1/EGFR/ATR/USP7/TFRC/TNFSF4/MAPK1/RTEL1/ACD/EYA4/KPNA1/MAP2K4/ERCC2/CTC1/SMC3/EXOSC3/GNL3L/RLF/HSP90AB1/CCNA2/MEN1/TEX15/LIG3/TBX21/PRKCQ/APLF/POT1/EXOSC6/BRCC3/AUNIP/MGMT/WAS/PAXIP1/NUDT16/ATAD5/USP37/UBE2B/ENDOG/GNL3/GJA1/GREM1/PNKP/NUCKS1/SPIDR/WT1/NEK7/ZRANB3/GRHL2/E2F8/TET1/FIGNL1/UPF1/BMPR2/MIR146A/ERCC8	186
BP	GO:0030833	regulation of actin filament polymerization	76/7096	162/18670	0.01244	0.06854	0.0511	MYADM/CDC42EP4/VASP/ARF6/HCK/RHOBTB1/PLEKHG2/TMSB10/SPIRE1/IQGAP2/ACTR2/TMOD3/HCLS1/EVL/TWF2/RDX/PFN1/CDC42EP2/PTK2B/CAPZA2/PRKCD/LATS1/GMFG/CORO1A/BAIAP2/ARFGEF1/CAPG/NCK1/FCHSD1/ARPC1A/CAPZA1/MKKS/ARPIN/SPTBN1/ARPC1B/CDC42EP3/CYFIP1/MYO1C/CORO1B/BBS4/ARF1/ARPC5L/COTL1/AVIL/KANK1/TRIOBP/ARHGAP18/ADD3/GRB2/JMY/ACTR3B/FER/DMTN/ACTR3/LMOD3/SCIN/PREX1/SLIT2/CCL26/ARPC4/SPTA1/SPTBN2/ARPC2/KANK3/MTOR/RHOA/PICK1/SNX9/CCR7/WAS/RHOBTB2/CCL24/BIN1/NCKAP1/FCHSD2/FMN1	76
BP	GO:0006086	acetyl-CoA biosynthetic process from pyruvate	11/7096	16/18670	0.0125	0.06854	0.0511	PDK4/PDK2/GSTZ1/MPC2/PDK1/PDHB/DLAT/PDP2/PDHA2/PDP1/PDPR	11
BP	GO:0006206	pyrimidine nucleobase metabolic process	11/7096	16/18670	0.0125	0.06854	0.0511	TYMP/ALDH6A1/CTPS2/DPYD/CMPK1/TYMS/MAPK1/CTPS1/CAD/CDA/MTOR	11
BP	GO:0009130	pyrimidine nucleoside monophosphate biosynthetic process	11/7096	16/18670	0.0125	0.06854	0.0511	UPP1/CDADC1/CMPK1/TYMS/SHMT1/UCK1/DCTD/CAD/UCKL1/UPP2/DUT	11
BP	GO:0010875	positive regulation of cholesterol efflux	11/7096	16/18670	0.0125	0.06854	0.0511	NFKBIA/APOE/NR1H2/ABCA1/LRP1/SIRT1/ABCG1/NR1H3/ABCA7/APOA1/PTCH1	11
BP	GO:0010934	macrophage cytokine production	11/7096	16/18670	0.0125	0.06854	0.0511	WNT5A/IRAK3/CD74/GPRC5B/LILRB1/TGFB1/CD36/TLR4/SIRT1/HLA-G/TGFB3	11
BP	GO:0032695	negative regulation of interleukin-12 production	11/7096	16/18670	0.0125	0.06854	0.0511	ACP5/LILRA5/IRAK3/NFKB1/LILRB1/SLAMF1/CMKLR1/TIGIT/MEFV/C1QBP/TLR8	11
BP	GO:0035372	protein localization to microtubule	11/7096	16/18670	0.0125	0.06854	0.0511	DIAPH1/ABHD17C/MAPRE1/MAPRE2/CHAMP1/KIF20B/MID2/CRIPT/DVL1/MAP1A/TTBK2	11
BP	GO:0035970	peptidyl-threonine dephosphorylation	11/7096	16/18670	0.0125	0.06854	0.0511	DUSP1/PPP2CA/DUSP5/DUSP10/DUSP18/PPM1D/PPM1F/DUSP4/PPP1CA/PDP1/PPM1G	11
BP	GO:0044794	positive regulation by host of viral process	11/7096	16/18670	0.0125	0.06854	0.0511	APOE/IGF2R/TBC1D20/CFL1/ANXA2P2/SMC3/PC/CSF1R/ANXA2/PPIB/NUCKS1	11
BP	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade	11/7096	16/18670	0.0125	0.06854	0.0511	IGF1/CAMTA1/CIB1/TNF/SLC9A1/NRG1/LMCD1/CHP2/LACRT/CHERP/ERBB3	11
BP	GO:0071545	inositol phosphate catabolic process	11/7096	16/18670	0.0125	0.06854	0.0511	INPP1/SYNJ1/SYNJ2/OCRL/NUDT3/INPP5K/IMPA2/MTMR2/NTSR1/INPP5A/IMPA1	11
BP	GO:0106058	positive regulation of calcineurin-mediated signaling	11/7096	16/18670	0.0125	0.06854	0.0511	IGF1/CAMTA1/CIB1/TNF/SLC9A1/NRG1/LMCD1/CHP2/LACRT/CHERP/ERBB3	11
BP	GO:1903830	magnesium ion transmembrane transport	11/7096	16/18670	0.0125	0.06854	0.0511	MRS2/NIPA2/CNNM2/NIPAL4/CNNM4/NIPA1/ZDHHC13/SLC41A1/TUSC3/NIPAL3/MMGT1	11
BP	GO:0006309	apoptotic DNA fragmentation	16/7096	26/18670	0.01267	0.06893	0.05139	AIFM1/DNASE2B/CASP3/NMNAT1/DFFA/HMGB1/IL6/DICER1/BAX/HMGB2/ST20/KPNA1/KPNB1/ENDOG/DNASE2/MIR146A	16
BP	GO:0006516	glycoprotein catabolic process	16/7096	26/18670	0.01267	0.06893	0.05139	MANBA/FBXO6/CST3/EDEM1/SGSH/MMP12/ADAMTS12/EDEM2/HPSE/STT3B/MAN1B1/NGLY1/FBXO27/FBXO44/EDEM3/ADAMTS9	16
BP	GO:0034114	regulation of heterotypic cell-cell adhesion	16/7096	26/18670	0.01267	0.06893	0.05139	KLF4/MYADM/MBP/FLOT1/CD44/TNF/MAPK7/IL1B/AGER/IL1RN/BMP7/LCK/APOA1/SKAP1/GCNT2/MAP2K5	16
BP	GO:1903203	regulation of oxidative stress-induced neuron death	16/7096	26/18670	0.01267	0.06893	0.05139	ATG7/PINK1/TSC1/FBXW7/SLC7A11/ATF4/HIF1A/MCL1/TLR4/NCOA7/FZD1/WNT1/NR4A3/LANCL1/TLR6/OXR1	16
BP	GO:1903579	negative regulation of ATP metabolic process	16/7096	26/18670	0.01267	0.06893	0.05139	CBFA2T3/FBP1/STAT3/NUPR1/PPARGC1A/FLCN/SLC25A12/MYOG/PFKFB1/HDAC4/DDIT4/PPARA/DNAJC15/PID1/RHOA/SNCA	16
BP	GO:0050920	regulation of chemotaxis	99/7096	217/18670	0.01269	0.06893	0.05139	FPR2/CCR2/RAC2/DUSP1/BST1/LYN/OXSR1/WNT5A/AZU1/SEMA4B/PTPN2/VEGFB/CAMK1D/S1PR1/MIF/LGMN/PLA2G7/GSTP1/CD74/CXCL10/ZSWIM6/CXCL12/PTPRO/DUSP3/MPP1/TGFB1/MEGF8/HSPB1/PTK2B/SWAP70/CXCL13/SEMA4A/VEGFA/CMKLR1/AIF1/SEMA4C/AGER/CCL5/SEMA4D/P2RY12/HMGB1/CCL7/PPM1F/RAC1/IL6/PDGFB/FGF1/IL16/MYCBP2/CORO1B/MIR34A/SEMA6B/C3AR1/MOSPD2/GPSM3/NRP1/SEMA3B/ZNF580/TMEM102/PRKD2/SERPINE1/CCR6/ITGA2/GPR18/CREB3/CCR4/LGALS9/SEMA5A/LPAR1/CALR/MST1/C1QBP/CXCR2/ADAM17/JAM3/SLIT2/CCL26/SEMA5B/TREM2/PLXNA3/HRG/SUCNR1/LBP/F3/TRPV4/C5AR2/GPR183/DAPK2/CCL19/MET/TIRAP/CCL4/CCR7/GREM1/SLAMF8/IL23A/PDGFD/S100A14/BMPR2	99
BP	GO:0071241	cellular response to inorganic substance	99/7096	217/18670	0.01269	0.06893	0.05139	CRHBP/NQO1/JUNB/SLC40A1/FOS/ALOX5AP/MEF2A/FBP1/FABP4/FOSB/AIFM1/WNT5A/SOD1/MCOLN1/SYT11/JUND/RASGRP2/PTGS2/MTR/LGMN/HFE/HMOX1/AKR1C3/PKD2/ATF4/ALAD/ZNF658/MAP1LC3A/CPNE8/NCF1/RYR1/CEBPA/HSPA5/CREB1/CRK/TRPM2/EIF2S1/ADCY7/LRRK2/PPARGC1A/SYT6/CLIC4/SUMO1/ADCY1/XRCC4/HVCN1/MYOG/CYP1A2/MAPK8/MMP9/DNM2/FUS/ID2/CDKN1B/MMP3/CYBB/TIMELESS/HNRNPD/LIG4/DMTN/CALR/SLC41A1/CACYBP/NFE2L2/NFE2L1/CAMK2D/EGFR/TPH2/SYT13/TRAF2/CPNE1/PRKAA1/FMR1/MAPK1/BAD/SYT9/RASAL1/CAPN3/ATP7A/CHP2/CPNE3/SLC25A24/SYT1/CPNE9/CCNA2/SYT2/SYT4/SYT5/CPNE2/APP/SNCA/SLC30A10/CHUK/ENDOG/CACNA1H/DAXX/SPIDR/MEF2C/MAPK9	99
BP	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	30/7096	56/18670	0.01271	0.06893	0.05139	CDKN1A/RGCC/BTG2/PLK2/SFN/PML/ATM/TNKS1BP1/MUC1/PLK3/PCNA/BAX/CRADD/CASP2/CDKN1B/CNOT4/PLAGL1/ARID3A/E2F4/CNOT7/GML/MDM2/RBL2/CNOT10/CARM1/TRIAP1/AURKA/SOX4/PRMT1/E2F8	30
BP	GO:0009435	NAD biosynthetic process	30/7096	56/18670	0.01271	0.06893	0.05139	HK3/NAMPT/QPRT/PARP9/PGK1/PFKM/PTGS2/PFKP/GAPDH/NMNAT3/PGAM1/PKM/TPI1/ALDOC/NMNAT1/ENO1/IDO1/ALDOA/PARP16/GPI/KYNU/HAAO/NMRK2/FOXK2/NMNAT2/IDO2/SLC5A8/ENO2/ADPGK/PFKL	30
BP	GO:0031295	T cell costimulation	30/7096	56/18670	0.01271	0.06893	0.05139	FYN/PTPN6/LYN/CSK/TNFRSF14/MAP3K8/DPP4/PAK1/TNFSF13B/PAK2/ICOSLG/EFNB1/RAC1/LCK/CTLA4/PDCD1LG2/LGALS1/GRB2/CD274/ICOS/VAV1/TNFSF4/CD5/TNFRSF13C/CD80/CCL19/CCR7/CD3E/PDCD1/CD24	30
BP	GO:0046148	pigment biosynthetic process	30/7096	56/18670	0.01271	0.06893	0.05139	WNT5A/FECH/SLC7A11/UROD/ZEB2/GMPS/ALAD/RAPGEF2/MYO5A/PAICS/ASIP/CPOX/TMEM14C/SRRD/PRPS1/GPR143/PPAT/COX15/IREB2/ADA/NFE2L1/SHMT1/DCT/ALAS1/CDH3/OCA2/SLC25A38/SLC25A39/APPL1/CTNS	30
BP	GO:0098586	cellular response to virus	30/7096	56/18670	0.01271	0.06893	0.05139	IRF7/BIRC2/DDX60/DDX58/MMP12/LSM14A/PUM2/ARF1/BCL2L11/NPLOC4/IFIH1/SEC14L1/ANKRD17/BIRC3/LGALS9/C1QBP/GPATCH3/RIOK3/FMR1/BAD/MAPK11/TRIM15/NLRX1/TRIM6/TSPAN6/CCL19/ADAR/CHUK/ZCCHC3/MIR146A	30
BP	GO:0048525	negative regulation of viral process	49/7096	99/18670	0.0128	0.06893	0.05139	TRIM32/ZFP36/FCN1/PLSCR1/STAT1/OASL/IFITM2/TNF/IFITM1/TRIM13/IFITM3/MORC2/ISG20/PTX3/TRIM26/TFAP4/OAS3/RSAD2/CCL5/SRPK2/PML/ISG15/TRIM11/APOBEC3G/MAVS/APOBEC3C/IFIT5/ILF3/BANF1/ZC3HAV1/TRIM21/CCL8/TNIP1/INPP5K/CCNK/MX1/SETDB1/RNASEL/IFIT1/SRPK1/EIF2AK2/MID2/TRIM15/TRIM6/EIF2AK4/CCL4/TARDBP/APCS/BTBD17	49
BP	GO:0008643	carbohydrate transport	70/7096	148/18670	0.01284	0.06893	0.05139	IGF1/PEA15/EZR/PLS1/APPL2/SLC5A3/MEF2A/AQP9/SLC45A4/TSC1/SLC23A2/SLC37A2/PPARD/PPBP/SLC45A3/SLC2A3/SLC37A4/SLC2A6/TNF/C2CD5/SLC2A9/TMEM144/SLC2A8/LEP/INSR/IL1B/SLC37A3/RAP1A/SLC35B4/SLC35D1/CREBL2/IRS2/RTN2/ITLN1/CLTCL1/GRB10/MFSD2A/PRKAG2/INPP5K/RHOQ/FFAR4/RNASEL/SLC50A1/SLC5A4/SLC17A5/SLC35B1/SLC35A3/NFE2L2/FABP5/ASPSCR1/SLC35C1/AQP3/ADIPOR2/SLC35A5/PID1/SLC2A10/HNF1A/NR4A3/TERT/STXBP3/SLC5A10/CLIP3/SLC5A9/SLC35A2/APPL1/SLC35D2/SLC5A2/KLF15/STXBP4/SESN2	70
BP	GO:0045913	positive regulation of carbohydrate metabolic process	42/7096	83/18670	0.0129	0.06893	0.05139	IGF1/PTPN2/PFKFB3/PMAIP1/SLC45A3/P2RX7/NFKB1/KAT2B/DYRK2/HIF1A/PTAFR/PPP1R3E/INSR/P2RY6/DDB1/SIRT1/DGAT2/IRS2/PDGFB/PFKFB4/DUSP12/PPARGC1A/SLC25A12/PFKFB1/PFKFB2/ARNT/PPARA/KAT2A/PRKAA1/PSEN1/BAD/IFNG/ESRRB/ZBTB20/APP/SNCA/CD244/GCG/ADCYAP1R1/WDR5/P2RY1/NTSR1	42
BP	GO:0071277	cellular response to calcium ion	42/7096	83/18670	0.0129	0.06893	0.05139	CRHBP/JUNB/FOS/ALOX5AP/MEF2A/FOSB/WNT5A/MCOLN1/SYT11/JUND/RASGRP2/LGMN/AKR1C3/PKD2/CPNE8/RYR1/HSPA5/TRPM2/SYT6/CLIC4/ADCY1/FUS/DMTN/CACYBP/CAMK2D/SYT13/CPNE1/PRKAA1/SYT9/RASAL1/CAPN3/CHP2/CPNE3/SLC25A24/SYT1/CPNE9/SYT2/SYT4/SYT5/CPNE2/ENDOG/MEF2C	42
BP	GO:0001783	B cell apoptotic process	15/7096	24/18670	0.01295	0.06893	0.05139	BCL10/LYN/BCL6/MIF/CD74/TNFRSF21/SLC39A10/IRS2/FNIP1/BCL2L11/BAX/NOC2L/ADA/FOXP1/BAK1	15
BP	GO:0008535	respiratory chain complex IV assembly	15/7096	24/18670	0.01295	0.06893	0.05139	SCO2/COA5/COX19/COX20/TIMM21/COX16/OXA1L/COA6/COX15/PET100/COA3/COA4/SURF1/COX14/SMIM20	15
BP	GO:0032878	regulation of establishment or maintenance of cell polarity	15/7096	24/18670	0.01295	0.06893	0.05139	RAP1B/RNF41/DOCK8/PTK2B/ARFGEF1/CDH5/FLOT2/KRIT1/WDPCP/BCAS3/KIF20B/KANK1/RUFY3/LLGL1/ROCK2	15
BP	GO:0036010	protein localization to endosome	15/7096	24/18670	0.01295	0.06893	0.05139	EZR/ARF6/PACSIN2/ABHD17C/RDX/MICALL1/DTX3L/NRP1/TOLLIP/MGAT3/LRRC7/RAB35/MSN/TMEM30A/ROCK2	15
BP	GO:0046174	polyol catabolic process	15/7096	24/18670	0.01295	0.06893	0.05139	GK/INPP1/TPI1/SYNJ1/SYNJ2/OCRL/NUDT3/GK5/INPP5K/IMPA2/MTMR2/SORD/NTSR1/INPP5A/IMPA1	15
BP	GO:0002902	regulation of B cell apoptotic process	12/7096	18/18670	0.01295	0.06893	0.05139	BCL10/LYN/BCL6/MIF/CD74/SLC39A10/IRS2/FNIP1/BAX/NOC2L/ADA/FOXP1	12
BP	GO:0010878	cholesterol storage	12/7096	18/18670	0.01295	0.06893	0.05139	STARD4/PPARD/SCARB1/SOAT1/CD36/NR1H2/ABCA1/EHD1/ABCG1/NR1H3/SREBF2/PPARA	12
BP	GO:0030809	negative regulation of nucleotide biosynthetic process	12/7096	18/18670	0.01295	0.06893	0.05139	CBFA2T3/FBP1/STAT3/NUPR1/PPARGC1A/FLCN/MYOG/PFKFB1/HDAC4/DDIT4/PPARA/PID1	12
BP	GO:0036035	osteoclast development	12/7096	18/18670	0.01295	0.06893	0.05139	SIGLEC15/NOTCH2/ATP6AP1/FBXW7/LILRB1/PAFAH1B1/TYROBP/ANXA2P2/CLDN18/ANXA2/FOXP1/SLC9B2	12
BP	GO:0039535	regulation of RIG-I signaling pathway	12/7096	18/18670	0.01295	0.06893	0.05139	BIRC2/DDX60/PUM2/NPLOC4/SEC14L1/ANKRD17/BIRC3/C1QBP/GPATCH3/TRIM15/NLRX1/ZCCHC3	12
BP	GO:0042095	interferon-gamma biosynthetic process	12/7096	18/18670	0.01295	0.06893	0.05139	CLEC7A/CEBPG/LILRB1/INHBA/EBI3/IL18/CD276/TLR8/TLR3/INHA/TNFRSF13C/IL12B	12
BP	GO:0044320	cellular response to leptin stimulus	12/7096	18/18670	0.01295	0.06893	0.05139	STAT3/ADIPOR1/LEP/BBS2/SIRT1/MKKS/BBS4/UGCG/PID1/NR4A3/CCNA2/FGF23	12
BP	GO:0051023	regulation of immunoglobulin secretion	12/7096	18/18670	0.01295	0.06893	0.05139	TMBIM6/CD40/TNF/CD22/TRAF6/HLA-E/GPI/IL6/TRAF2/TNFSF4/TNFRSF4/RBP4	12
BP	GO:0070230	positive regulation of lymphocyte apoptotic process	12/7096	18/18670	0.01295	0.06893	0.05139	WNT5A/P2RX7/ADAM8/PRELID1/IDO1/NFKBID/CCL5/FNIP1/BAX/CD274/LGALS9/PDCD1	12
BP	GO:0071371	cellular response to gonadotropin stimulus	12/7096	18/18670	0.01295	0.06893	0.05139	GCLM/POR/HMGCS1/PAX8/GCLC/PPARGC1A/EPHA8/INHBA/NSMF/CCNA2/FSHR/WT1	12
BP	GO:1900221	regulation of amyloid-beta clearance	12/7096	18/18670	0.01295	0.06893	0.05139	TNF/APOE/HMGCR/LRPAP1/SRF/LRP1/CLU/MIR34A/ABCA7/IFNGR1/TREM2/IFNG	12
BP	GO:1900372	negative regulation of purine nucleotide biosynthetic process	12/7096	18/18670	0.01295	0.06893	0.05139	CBFA2T3/FBP1/STAT3/NUPR1/PPARGC1A/FLCN/MYOG/PFKFB1/HDAC4/DDIT4/PPARA/PID1	12
BP	GO:2000757	negative regulation of peptidyl-lysine acetylation	12/7096	18/18670	0.01295	0.06893	0.05139	SPI1/SIN3A/ZNF451/SIRT1/HDAC2/NOC2L/BRCA1/HINT2/SET/SNCA/KLF15/TAF7	12
BP	GO:0008380	RNA splicing	202/7096	469/18670	0.01299	0.06893	0.05139	CELF6/TRA2B/PCF11/PPP2CA/NSRP1/JMJD6/SRSF5/TMBIM6/CLASRP/PRPF4/DDX20/PRPF38A/U2SURP/FAM98B/KHDRBS1/CSTF3/HNRNPR/METTL14/HNRNPH1/ALYREF/PPIL1/DAZAP1/RNPS1/THRAP3/HNRNPH3/PPP4R2/RBM7/MAGOHB/ZBTB7A/PCBP1/RBM42/RP9/AKAP17A/SRSF10/ZNF326/ZNF830/CWF19L2/LSM5/CRNKL1/WDR83/METTL3/HNRNPK/MBNL1/YTHDC1/RBM4/RBM4B/AHNAK/COIL/SYF2/HABP4/SNRNP25/SNRNP200/CWF19L1/HNRNPA1/CACTIN/HNRNPA2B1/ZPR1/RBM8A/SNUPN/SNRPB/GEMIN6/TXNL4A/DHX9/U2AF1/GTF2F2/SRPK2/LUC7L/SFSWAP/SRSF3/GEMIN7/SNRPA1/RNF113A/BCAS2/POLR2L/SYMPK/BUD31/RBM39/SFPQ/HNRNPUL1/DHX8/USB1/CPSF3/RBM41/PDCD7/MBNL3/PPARGC1A/CLP1/CD2BP2/POLR2H/RBMXL1/PAPOLA/SCAF8/LSM7/SNIP1/RBM3/SNRPD1/PRPF3/USP4/SETX/SNRPA/PUF60/SNRPC/DCPS/ZCCHC8/MFAP1/ISY1/RSRC1/CWC22/SNRPB2/HNRNPC/FIP1L1/IVNS1ABP/STRAP/PRPF40B/PRPF40A/FUS/THOC2/HNRNPA0/LUC7L2/SRSF6/PRDX6/SREK1/SNRPF/SRSF7/DDX1/DDX46/RALY/CDC40/PRPF8/PCBP2/SF3A3/GTF2F1/CWC25/SMNDC1/SF3B4/CSTF1/SRPK1/HNRNPD/POLR2F/WEE2-AS1/PRMT5/AAR2/HNRNPM/THOC5/POLR2D/PRX/TGS1/PRPF31/RBMXL2/C1QBP/U2AF1L4/RBMX2/THOC6/SART1/SRRM1/POLR2K/FMR1/LOC100128988/BRDT/ZRANB2/CELF2/WDR77/USP49/UBL5/SRSF4/WBP11/ZC3H10/RBM25/CLNS1A/DHX38/HNRNPA3/SUGP1/GPKOW/CPSF2/PRPF19/CELF3/HMX2/CLK1/SRRM4/ERN1/C2orf49/PRPF39/SAP18/CPSF1/SNRPN/ZCRB1/AQR/CPSF7/PPWD1/IK/CHERP/SRRT/DHX16/EFTUD2/POLR2I/LUC7L3/SYNCRIP/TARDBP/WT1/SNRPG/SON/SNRPD2	202
BP	GO:0050709	negative regulation of protein secretion	67/7096	141/18670	0.01299	0.06893	0.05139	FN1/EZR/PTGER4/IL27RA/ANXA1/IL1R2/RHBDF2/GBP1/ARG2/SYT11/ERP29/TMBIM6/DPH3/LILRA5/NLRP3/HADH/TNFAIP3/BANK1/SIRT4/LGR4/ENY2/NLRP12/RGCC/FAM3D/TNF/TNFRSF21/APOE/HMGCR/LILRB1/CD22/PIM3/ENHO/SERPINB1/MAPKBP1/PTPN22/RSAD2/IL1B/PML/CD200R1/KLF7/IDH2/NR1H3/FFAR4/SYTL4/RABGEF1/BTN2A2/CPTP/F2R/PPP1R11/TLR8/SRGN/APOA1/TNFRSF4/FRMD4A/CD34/SYT4/NDUFAF2/MAP4K4/C5AR2/CX3CL1/PFKL/NR1H4/TLR6/PSMD9/C1QTNF3/GHRL/RHBDF1	67
BP	GO:1901989	positive regulation of cell cycle phase transition	52/7096	106/18670	0.01302	0.06893	0.05139	ANXA1/CCND3/RAB11A/MEPCE/DDRGK1/RGCC/EZH2/LSM11/PAF1/CCND2/TMOD3/CDK4/TGFB1/RDX/SIN3A/MTA3/DBF4B/NPM1/RAD51B/AIF1/NSMCE2/CCND1/ESPL1/DDX3X/ANAPC5/KMT2E/UBE2E2/CCNE1/ANKRD17/CDC25A/VPS4B/UBE2C/DTL/DYRK3/PLCB1/EGFR/ADAM17/RCC2/MDM2/DLGAP5/EIF4G1/ANAPC4/MTBP/CUL4B/RB1/TERT/ANAPC11/APP/CDC73/ATAD5/WNT10B/STXBP4	52
BP	GO:0007204	positive regulation of cytosolic calcium ion concentration	141/7096	319/18670	0.01304	0.06893	0.05139	SLC8A1/FPR2/HTR2B/FPR1/CCR2/FYN/CX3CR1/PTGER4/PTPN6/S1PR4/ATP2B4/LYN/CD55/MCOLN1/S1PR3/PTGER2/TPCN1/DIAPH1/TMBIM6/GNB1/S1PR1/GNA15/ACKR3/P2RY8/CXCL9/JAK2/CXCL11/PTPRC/P2RX7/BCAP31/CXCL10/PKD2/TGFB1/ITPR1/FIS1/CD36/LPAR2/PTK2B/MYO5A/SWAP70/CORO1A/P2RY6/CXCL13/RYR1/CDK5/ABL1/CMKLR1/GSTO1/PLCG2/PML/CYSLTR1/LRP1/HMGB1/DMD/TRPM4/NPTN/TRPM2/LPAR6/CXCR1/LCK/CCR5/SRI/RASA3/C3AR1/NMUR2/BCL2/TGM2/BAX/MS4A1/CHRNA10/CCR6/PRKACA/LPAR3/GPR18/CXCR6/CCR4/CYBA/LPAR1/MCOLN2/PROK2/F2R/GRIN2C/CAMK2D/PLCB1/CCR3/CEMIP/CXCR2/ABL2/NMB/CAV3/LETM1/GIPR/TACR1/GNA13/GPR35/GALR1/P2RY4/CASQ1/PLA2G6/CAPN3/CASQ2/HRC/BDKRB1/CD4/TMEM38B/LACRT/PIK3CG/CACNB3/OPRL1/LIME1/P2RY10/TRPV4/C5AR2/GPR6/SNCA/CX3CL1/IAPP/CXCR3/P2RX2/CIB2/CCL19/CCKBR/BAK1/CHERP/ATP1A2/CCR7/SLC8A3/MCOLN3/FAM155A/GJA1/ACKR2/GPR20/ADCYAP1R1/CCRL2/CD24/P2RY1/NTSR1/GHRL/KISS1/P2RX5/SYNPO	141
BP	GO:0018210	peptidyl-threonine modification	64/7096	134/18670	0.01311	0.06893	0.05139	OXSR1/WNT5A/AZU1/SMAD7/MAP2K1/CSNK1G2/DYRK4/VRK2/GSK3B/DYRK2/CSNK2A2/UBE2K/TGFB1/CSNK1D/PRKCD/DYRK1B/CDK5/NLK/MAP3K12/CSNK2B/BMP7/CHI3L1/TTBK1/ACVR1B/LRRK2/TNKS1BP1/CSNK1A1/CSNK1E/SPHK1/PRKAG2/MAPK8/BCL2/PRKD2/INPP5K/MARK2/PRKACA/CSNK1G3/DDIT4/HIPK1/CAMK2A/DMTN/SPRED1/DYRK3/CAMK2D/CEMIP/ULK1/SPRY2/MAPK1/VRK1/EIF4G1/PPEF2/CAD/LMTK2/HIPK3/TRIM6/MTOR/CLK1/APP/TTBK2/GALNT1/GCG/ROCK2/CSNK1G1/PRKCA	64
BP	GO:0021801	cerebral cortex radial glia guided migration	14/7096	22/18670	0.01312	0.06893	0.05139	SUN2/MBOAT7/CDK5/PAFAH1B1/SRGAP2C/P2RY12/SYNE2/SRGAP2/DISC1/DAB1/CDK5R2/NR2E1/RELN/RTN4	14
BP	GO:0022030	telencephalon glial cell migration	14/7096	22/18670	0.01312	0.06893	0.05139	SUN2/MBOAT7/CDK5/PAFAH1B1/SRGAP2C/P2RY12/SYNE2/SRGAP2/DISC1/DAB1/CDK5R2/NR2E1/RELN/RTN4	14
BP	GO:0032928	regulation of superoxide anion generation	14/7096	22/18670	0.01312	0.06893	0.05139	ITGAM/FPR2/ACP5/CLEC7A/SOD1/GNAI3/GSTP1/TGFB1/PRKCD/TYROBP/AATF/GNAI2/CYBA/EGFR	14
BP	GO:0033233	regulation of protein sumoylation	14/7096	22/18670	0.01312	0.06893	0.05139	HMG20A/EGR1/RELA/HDAC4/TOLLIP/ARNT/PIAS3/MUL1/CAPN3/UBE2I/GNL3L/HMG20B/GNL3/RASD2	14
BP	GO:0046599	regulation of centriole replication	14/7096	22/18670	0.01312	0.06893	0.05139	NUP62/KAT2B/TRIM37/PLK2/NPM1/CDK5RAP2/CEP76/SPICE1/CHMP2A/VPS4B/BRCA1/KAT2A/CEP120/ALMS1	14
BP	GO:0002577	regulation of antigen processing and presentation	13/7096	20/18670	0.01313	0.06893	0.05139	NOD2/LILRB2/SLC11A1/FGL2/HFE/CD74/HLA-DOB/TAPBPL/TREM2/CCL19/CCR7/WAS/HLA-DOA	13
BP	GO:0016137	glycoside metabolic process	13/7096	20/18670	0.01313	0.06893	0.05139	FUCA1/CBR4/AKR1B1/AKR1C3/AKR7A2/AKR1A1/AKR1C1/GLA/GUSB/NAGA/AKR1B10/FUCA2/ABHD10	13
BP	GO:0033617	mitochondrial respiratory chain complex IV assembly	13/7096	20/18670	0.01313	0.06893	0.05139	SCO2/COA5/COX19/COX20/TIMM21/COX16/OXA1L/PET100/COA3/COA4/SURF1/COX14/SMIM20	13
BP	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	13/7096	20/18670	0.01313	0.06893	0.05139	SRF/PSMC4/SUB1/CREB1/PSMC3/CAND1/PSMC6/HNF1B/HNF1A/PSMC5/PSMC2/PAXIP1/WNT10B	13
BP	GO:0070262	peptidyl-serine dephosphorylation	13/7096	20/18670	0.01313	0.06893	0.05139	DUSP1/PPP2CA/PPP1R15A/SWAP70/NCK1/PPM1F/PPP1R15B/PPP1R16B/PPP2R2D/PPP2R2B/PPP1CA/YWHAE/PPP2R2C	13
BP	GO:1902993	positive regulation of amyloid precursor protein catabolic process	13/7096	20/18670	0.01313	0.06893	0.05139	LYN/TNF/CASP3/AGER/CLU/ABCG1/IFNGR1/IFNG/APP/GSAP/PICALM/ROCK2/EFNA3	13
BP	GO:1903978	regulation of microglial cell activation	13/7096	20/18670	0.01313	0.06893	0.05139	GRN/CTSC/PTPRC/MIR142/LDLR/TTBK1/IL6/LRRK2/CST7/ATM/SPHK1/TREM2/CX3CL1	13
BP	GO:0043507	positive regulation of JUN kinase activity	38/7096	74/18670	0.01314	0.06893	0.05139	WNT5A/DVL2/TNF/ERCC6/ZEB2/MAP3K4/TAOK3/PAK1/MAP4K5/PTK2B/ROR2/TRAF6/AGER/MAP3K12/MDFIC/TNFRSF11A/DUSP19/MAP4K2/MAP3K6/MAP4K1/MLKL/MAP3K11/FZD5/BIRC7/MAP3K5/MUL1/TRAF2/FZD4/MAP2K4/MAP3K13/ERN1/CCL19/DAXX/TLR6/FZD10/NRK/SASH1/MAP3K9	38
BP	GO:0060998	regulation of dendritic spine development	38/7096	74/18670	0.01314	0.06893	0.05139	SIPA1L1/ARF6/DNM3/APOE/ACTR2/LRP8/UBE3A/BAIAP2/ITSN1/CDK5/PLK2/PAFAH1B1/SRGAP2C/CAPRIN1/KALRN/LRRK2/ARC/ARF1/PDLIM5/HDAC2/DISC1/CFL1/SHANK1/CPEB3/LPAR1/FSTL4/BHLHB9/DNM1L/PSEN1/FMR1/RELN/MTOR/C21orf91/ASAP1/SHANK3/ZMYND8/MEF2C/CAMK2B	38
BP	GO:0006904	vesicle docking involved in exocytosis	24/7096	43/18670	0.01324	0.06918	0.05157	CTBP2/EXOC6B/STXBP1/UNC13B/STXBP2/VAMP3/VPS33A/BLOC1S6/RAB8A/VPS18/PLEK/CAMK2A/YKT6/RAB8B/RAB3A/PPFIA3/VTI1B/SYTL2/EXOC4/RAB3B/SCFD1/STXBP3/RABEPK/RAB3D	24
BP	GO:0009163	nucleoside biosynthetic process	24/7096	43/18670	0.01324	0.06918	0.05157	TYMP/UPP1/GMPS/ADK/GUK1/IMPDH1/CTPS2/CMPK1/TK1/PRTFDC1/NME3/MTAP/NME4/NME1/ADA/DCK/UCK1/TK2/CTPS1/CAD/CDA/UCKL1/UPP2/ADAL	24
BP	GO:0045429	positive regulation of nitric oxide biosynthetic process	24/7096	43/18670	0.01324	0.06918	0.05157	KLF4/KLF2/CLEC7A/PTGS2/JAK2/TNF/DDAH2/PKD2/TICAM1/CD36/PTK2B/INSR/HBB/PTX3/TLR4/IL1B/AIF1/CLU/DNM2/AGXT2/IFNG/HSP90AB1/MTOR/TLR6	24
BP	GO:0051293	establishment of spindle localization	24/7096	43/18670	0.01324	0.06918	0.05157	SPIRE1/SPDL1/MAP4/UBXN2B/PAFAH1B1/CDK5RAP2/SAPCD2/NSFL1C/ARHGEF2/ESPL1/MYH9/BCCIP/NDC80/NDEL1/NUSAP1/ZW10/SPRY1/MOS/GPSM2/SPRY2/LLGL1/CENPA/MISP/KPNB1	24
BP	GO:1904646	cellular response to amyloid-beta	24/7096	43/18670	0.01324	0.06918	0.05157	IGF1/FPR2/FYN/NAMPT/LGMN/GSK3B/CD36/ITGA4/TLR4/IGF1R/CDK5/AGER/LRP1/SNX6/BCL2L11/ADRB2/CASP4/PSEN1/TREM2/APP/BCL2L2/TLR6/FOXO3/MIR146A	24
BP	GO:0071674	mononuclear cell migration	45/7096	90/18670	0.01337	0.06982	0.05205	FPR2/S100A12/CCR2/DUSP1/ANXA1/LYN/FLT1/LGMN/PLA2G7/TNF/CXCL10/CXCL12/PTPRO/TGFB1/CMKLR1/AIF1/AGER/CCL5/HMGB1/TNFRSF11A/CCL7/IL6/PDGFB/RPS19/C3AR1/MOSPD2/CCL13/BMP5/CCL8/SERPINE1/CD47/CREB3/PLCB1/CCL20/SLIT2/CCL26/TRPV4/CX3CL1/CCL19/CCL4/GREM1/CCL24/SLAMF8/PDGFD/S100A14	45
BP	GO:0001894	tissue homeostasis	103/7096	227/18670	0.01341	0.06996	0.05215	EPAS1/SPATA7/NOD2/SIGLEC15/CCR2/PIP/TRIM32/RAC2/PDK4/ACP5/CSK/SOD1/DRAM2/ATP6AP1/AKR1B1/TPP1/BARD1/SPP1/TNFAIP3/S1PR1/LIPA/SNX10/SLC22A5/CTSK/LDB1/P2RX7/ADAM8/ERCC6/GIGYF2/KRAS/BBS10/PBLD/CHMP4B/ACTB/CLN8/ZNF830/HSPB1/PTK2B/PRDX1/SRF/CORO1A/TRAF6/FLT3LG/TCIRG1/PIWIL4/IL20RB/TLR4/TP53INP2/VEGFA/LTBP3/CYTL1/TNFRSF11A/BBS2/MUC2/BBS12/IL7/MKKS/HOMER1/RAC1/PLEKHM1/IL6/RDH12/BBS4/TMEM64/NPHP4/MAK/STRAP/BCL2/FH/BAX/ADRB2/WDR36/MKS1/F2R/LCA5/ANKRD11/EGFR/COL2A1/TFRC/DCSTAMP/MUC6/NXNL1/CLDN18/GCNT2/CD34/RB1/LACRT/ESRRB/CSF1R/CDH3/RAB3D/IAPP/CIB2/LPCAT1/TULP1/CCDC66/TMEM119/SMO/PRKCA/RBP4/RP1/POC1B/ALB	103
BP	GO:0034250	positive regulation of cellular amide metabolic process	72/7096	153/18670	0.0135	0.07036	0.05245	PINK1/VIM/PPP1R15A/TNF/KHDRBS1/YTHDF3/PAIP1/EIF6/CDK4/UQCC1/PTAFR/PTK2B/PRKCD/METTL3/CNBP/EIF2B5/HABP4/NCK1/CASP3/NPM1/LARP4/GUF1/UQCC2/CCL5/DHX9/CLU/IL6/NAT10/DDX3X/SERP1/RBM3/RPS9/PLK3/RXRA/USP16/TARBP2/ABCG1/PRR16/ITGA2/ZCCHC4/HNRNPD/CPEB3/YBX3/POLR2D/NFE2L2/IMPACT/COA3/IFNGR1/LARP4B/C1QBP/EIF5A/NGRN/FMR1/MAPK1/PLA2G6/RPUSD3/IFNG/RPS6KB2/JMJD4/EIF2AK4/MTOR/RHOA/APP/SAMD4A/SOX4/GSAP/TRMT10C/MPV17L2/SMPD2/PICALM/ROCK2/BOLL	72
BP	GO:0051262	protein tetramerization	80/7096	172/18670	0.01356	0.07056	0.05261	S100A10/PKD2L1/VASP/ACOT13/APPL2/FBP1/CBR4/MCOLN1/SYT11/ALDH9A1/PFKM/PFKP/HMGCL/ACPP/ME1/CD74/PCBD1/GBP5/PKD2/HMGCR/PKM/EVL/APIP/INSR/CBY1/RYR1/DECR1/IGF1R/CAT/ALDOA/PDSS1/SAMHD1/CCL5/GPX3/TK1/ACACB/CRTC2/TRPM4/TRPM2/HOMER1/RCC1/ALDH5A1/CRTC1/CRTC3/RPS19/SHMT2/RXRA/USP16/CD247/HSD17B10/HINT3/CTH/MS4A1/OXA1L/KRT10/PPAT/OSBPL2/RRM2/GLS/DNM1L/CUTC/SHMT1/PEX14/ANXA2P2/XRCC6/SRR/CDA/DCTPP1/PCBD2/ANXA2/SBF2/SNCA/ST13/CRYZ/HCN1/CPSF7/LRP4/PFKL/TDO2/MAT1A	80
BP	GO:0097345	mitochondrial outer membrane permeabilization	29/7096	54/18670	0.01357	0.07056	0.05261	BMF/SLC35F6/BLOC1S2/PMAIP1/YWHAH/TMEM14A/GSK3B/MPV17L/FZD9/SFN/CASP8/RHOT2/CHCHD10/SLC25A5/BCL2L11/MAPK8/TMEM102/BCL2/BAX/GZMB/YWHAQ/MUL1/ACAA2/YWHAE/BAD/PPP1R13B/MOAP1/YWHAG/BAK1	29
BP	GO:1904645	response to amyloid-beta	29/7096	54/18670	0.01357	0.07056	0.05261	IGF1/FPR2/FYN/NAMPT/LGMN/GSK3B/CD36/ITGA4/TLR4/IGF1R/CDK5/AGER/MMP12/LRP1/SNX6/BCL2L11/DNM1/MMP9/MMP3/ADRB2/CASP4/PSEN1/TREM2/MMP2/APP/BCL2L2/TLR6/FOXO3/MIR146A	29
BP	GO:0030316	osteoclast differentiation	48/7096	97/18670	0.01371	0.0712	0.05308	JUNB/FOS/SIGLEC15/SBNO2/NOTCH2/ATP6AP1/KLF10/LILRB3/SNX10/FBXW7/CEBPB/TNF/SH3PXD2A/LILRB1/TGFB1/OSCAR/LILRB4/TRAF6/TCIRG1/TLR4/PAFAH1B1/MITF/TNFRSF11A/CREB1/TYROBP/TFE3/OSTM1/TMEM64/IREB2/PIAS3/TFRC/ANXA2P2/DCSTAMP/LRRC17/TREM2/IFNG/CLDN18/TLR3/IL12B/CSF1R/ANXA2/MTOR/FOXP1/GPR183/SLC9B2/EFNA2/IL23A/CD109	48
BP	GO:1902882	regulation of response to oxidative stress	48/7096	97/18670	0.01371	0.0712	0.05308	FYN/GCH1/ATG7/PINK1/TSC1/SOD1/FBXW7/PSAP/TNF/SLC7A11/ATF4/HGF/HIF1A/HSPB1/CD36/MAPK7/MCL1/HTRA2/TLR4/NCOA7/ACOX2/SIRT1/SFPQ/BMP7/LRRK2/MIR34A/VNN1/MMP3/FZD1/NFE2L2/DHFR/TXN/SESN1/GGT7/WNT1/NR4A3/MAPKAP1/LANCL1/GPX1/PDE8A/BAG5/ABCD1/MET/ENDOG/SESN2/TLR6/FOXO3/OXR1	48
BP	GO:0007093	mitotic cell cycle checkpoint	77/7096	165/18670	0.01386	0.07191	0.05361	DUSP1/CDKN1A/MAD2L2/DYNC1LI1/RGCC/HUS1B/NABP1/SPDL1/GIGYF2/BTG2/TGFB1/TAOK3/ZNF830/SYF2/SETMAR/CDKN2B/PLK2/SFN/KLHL22/HRAS/CDK5RAP2/DONSON/PML/TIPIN/CCND1/ZNF207/LCMT1/ATM/TNKS1BP1/BUB3/MUC1/PLK3/RAD17/NDC80/PCNA/BAX/ZWILCH/CRADD/CASP2/RFWD3/CDKN1B/MAD2L1BP/TOP2B/CNOT4/PLAGL1/GEN1/ARID3A/ZW10/INTS3/FOXO4/TICRR/E2F4/BRCA1/CNOT7/GML/MDM2/CLSPN/WEE1/RPL24/RBL2/RAD9A/TOPBP1/CDC20/PCID2/RB1/CNOT10/CARM1/TRIAP1/AURKA/BRSK1/SOX4/IK/PRMT1/CHFR/ZFYVE19/E2F8/TOP2A	77
BP	GO:1901215	negative regulation of neuron death	95/7096	208/18670	0.01389	0.07198	0.05366	FYN/CX3CR1/GRN/ATG7/NR4A2/PINK1/GCLM/TSC1/SOD1/GPNMB/STAT3/ALKBH1/LGMN/CEBPB/JAK2/ADAM8/SLC7A11/HMOX1/KRAS/APOE/GSK3B/BTG2/REL/ATF4/AXL/CHMP4B/STXBP1/ARRB1/HIF1A/WFS1/PTK2B/HLA-F/CORO1A/IKBKG/HTRA2/ITSN1/FZD9/PARP2/CDK5/HRAS/NMNAT1/GCLC/ZPR1/NCOA7/CLN3/MAP3K12/LRP1/CREB1/SIRT1/LRRK2/CD200R1/PPARGC1A/SNX6/NRP1/BCL2/KDM2B/BAX/CLCF1/SYNGAP1/UNC5B/LIG4/BHLHB9/F2R/FZD1/CNTF/PPARA/TRAF2/WNT1/PSEN1/CNTFR/STAMBP/PSMC1/MAP2K4/EIF4G1/TGFB3/FAIM2/NR4A3/HYOU1/PIN1/CD34/HSP90AB1/SET/TERT/RHOA/TYRO3/SNCA/CX3CL1/PTPRZ1/SLC30A10/ERBB3/KIF14/NTRK2/MEF2C/OXR1/GDF5	95
BP	GO:0010721	negative regulation of cell development	151/7096	344/18670	0.0139	0.07198	0.05366	IGF1/RTN4R/DPYSL3/DLL1/APPL2/ARF6/SKI/DNM3/WNT5A/DENND5A/TSC1/GBP1/S1PR3/HMG20A/STAT3/SEMA4B/VIM/LRIG2/SPP1/DUSP10/RNF10/CIB1/ULK2/FBXW7/ACTN4/RGS2/YWHAH/CERS2/TNF/EPHB2/ARHGDIA/IFRD1/APOE/GSK3B/LILRB1/PTPRO/NOTCH3/MIB1/UBE3A/TGFB1/DGUOK/CTNNA1/PAK1/RAPGEF2/PCM1/BCL11A/NRG1/MBD1/SEMA4A/ASCL2/VEGFA/DTX1/CDK5/PLK2/TRAK2/PAFAH1B1/CTSZ/CDK5RAP2/SRGAP2C/IL1B/GDI1/SEMA4C/LDLR/ARHGEF2/PAQR3/SEMA4D/LRP1/HEY1/TRIM11/BMP7/RAB29/IL6/CTDP1/LRRK2/DCC/G6PD/IDH2/ASPM/PTK2/DICER1/DIXDC1/SEMA6B/SRGAP2/HDAC2/BMPR1A/NRP1/SEMA3B/HOOK3/BCL2/ID2/CTDSP1/KCTD11/YY1/CNTN4/KANK1/LGALS1/SYNGAP1/DAB1/INPP5F/RTN4RL1/PITX3/SEMA5A/LPAR1/DMTN/HES1/FSTL4/CORO1C/CALR/CNTF/PPARA/RCC2/CAV3/TLX3/SLIT2/PSEN1/MDM2/SEMA5B/RTN4RL2/EIF4E/RUFY3/PLXNA3/SPOCK1/PTHLH/CLDN18/NR2F1/TACSTD2/CARM1/TERT/MEIS1/EIF2AK4/NR2E1/SYT4/MAP4K4/RHOA/TRPV4/APP/RTN4/CX3CL1/ITGB1BP1/BAG5/KREMEN1/ASAP1/LMX1A/FGF13/LRP4/WNT7A/EIF4ENIF1/DAAM2/FOXO3/TRIM46/MIR146A	151
BP	GO:0042552	myelination	63/7096	132/18670	0.01401	0.0723	0.0539	TYMP/TLR2/HEXB/MPP5/SKI/ZSCAN26/TSC1/SOD1/CMTM8/MBP/RNF10/CTSC/PSAP/TNFRSF21/TGFB1/HGF/GALC/MYO5A/NRG1/B4GALT6/EIF2B5/ZNF24/FIG4/FAM126A/NAB1/ZPR1/ATRN/S100B/MARVELD1/CLU/AFG3L2/NDRG1/ZNF488/EGR2/CST7/DICER1/SLC25A12/ADAM22/SH3TC2/MTMR2/LGI4/B4GALT5/LPAR1/MALL/AMIGO1/JAM3/ACER3/ERCC2/GNPAT/SCN8A/MTOR/SBF2/DAG1/ABCD1/TSPAN2/PTPRZ1/SLC8A3/EIF2B2/PLP1/KEL/KIF14/NTRK2/POU3F1	63
BP	GO:0021575	hindbrain morphogenesis	23/7096	41/18670	0.01403	0.0723	0.0539	DLL1/MAP2K1/LDB1/HSPA5/CDK5/ABL1/OPHN1/XRCC1/DAB1/HES1/WNT1/CBLN1/RORA/GNPAT/FAIM2/ATP7A/SPTBN2/KNDC1/TRNP1/WNT7A/AGTPBP1/SMO/KIF14	23
BP	GO:0090317	negative regulation of intracellular protein transport	23/7096	41/18670	0.01403	0.0723	0.0539	BARD1/CHP1/SIRT4/RAB23/CD36/CDK5/SP100/GDI1/UBE2J1/MDFIC/UBE2G2/LRRK2/INPP5K/LMAN1/DMTN/DERL2/INSIG1/TXN/YOD1/PKIA/ITGB1BP1/ERLEC1/OS9	23
BP	GO:0097178	ruffle assembly	23/7096	41/18670	0.01403	0.0723	0.0539	ARF6/SNX10/EVL/RDX/PFN1/RHOG/HRAS/FAM98A/AIF1/P2RY12/RAC1/PLEKHM1/CYFIP1/SH3YL1/WDPCP/INPP5K/KANK1/NDEL1/CORO1C/RCC2/TACSTD2/EPS8L2/INPPL1	23
BP	GO:1902893	regulation of pri-miRNA transcription by RNA polymerase II	23/7096	41/18670	0.01403	0.0723	0.0539	FOS/SPI1/STAT3/PPARD/RELA/TGFB1/NFATC3/HIF1A/SRF/LILRB4/BMP2/PDGFB/BMPR1A/BMP4/HDAC4/YY1/KLF5/SREBF2/PPARA/TERT/GNL3/WT1/APLN	23
BP	GO:0031571	mitotic G1 DNA damage checkpoint	33/7096	63/18670	0.01404	0.0723	0.0539	CDKN1A/RGCC/GIGYF2/BTG2/PLK2/SFN/PML/CCND1/ATM/TNKS1BP1/MUC1/PLK3/PCNA/BAX/CRADD/CASP2/RFWD3/CDKN1B/CNOT4/PLAGL1/ARID3A/E2F4/CNOT7/GML/MDM2/RBL2/CNOT10/CARM1/TRIAP1/AURKA/SOX4/PRMT1/E2F8	33
BP	GO:0044819	mitotic G1/S transition checkpoint	33/7096	63/18670	0.01404	0.0723	0.0539	CDKN1A/RGCC/GIGYF2/BTG2/PLK2/SFN/PML/CCND1/ATM/TNKS1BP1/MUC1/PLK3/PCNA/BAX/CRADD/CASP2/RFWD3/CDKN1B/CNOT4/PLAGL1/ARID3A/E2F4/CNOT7/GML/MDM2/RBL2/CNOT10/CARM1/TRIAP1/AURKA/SOX4/PRMT1/E2F8	33
BP	GO:0031929	TOR signaling	60/7096	125/18670	0.01409	0.07251	0.05406	PINK1/TSC1/C9orf72/SIK1/PRR5/SH3BP4/WDR24/HIF1A/TNFAIP8L1/SEH1L/LEP/SYAP1/KLHL22/LAMTOR1/SIK2/ARAF/RRAGD/NPRL3/SIRT1/TBCK/EIF4EBP2/CCDC88A/KPTN/MLST8/FLCN/ATM/TMEM127/MAPKAPK5/FNIP1/LAMTOR4/EPM2A/DISC1/AKT1S1/TBC1D7/RFFL/DDIT4/RRAGA/ZMPSTE24/LAMTOR5/DYRK3/ITFG2/SESN1/DEPTOR/PRKAA1/TELO2/UBR1/SMCR8/NPRL2/TREM2/ARNTL/RPS6KB2/PKHD1/MAPKAP1/CLEC16A/RELN/MTOR/DEPDC5/SESN2/TTI1/SLC38A9	60
BP	GO:0022404	molting cycle process	44/7096	88/18670	0.01433	0.07352	0.05481	RBPJ/WNT5A/LGR4/LDB1/TNF/RELA/MYO5A/SOX21/FUZ/INTU/TRADD/NSUN2/GORAB/SAV1/ACVR1B/EDA/HPSE/HDAC2/EDAR/BCL2/INHBA/PDGFA/ZMPSTE24/EGFR/DNASE1L2/LGR5/ERCC2/SNAI1/TMEM79/ATP7A/KRT27/CDH3/FOXN1/KRT84/WNT10A/TRPC4AP/LRP4/ZDHHC21/WNT10B/APCDD1/SMO/LRIG1/NOM1/CD109	44
BP	GO:0022405	hair cycle process	44/7096	88/18670	0.01433	0.07352	0.05481	RBPJ/WNT5A/LGR4/LDB1/TNF/RELA/MYO5A/SOX21/FUZ/INTU/TRADD/NSUN2/GORAB/SAV1/ACVR1B/EDA/HPSE/HDAC2/EDAR/BCL2/INHBA/PDGFA/ZMPSTE24/EGFR/DNASE1L2/LGR5/ERCC2/SNAI1/TMEM79/ATP7A/KRT27/CDH3/FOXN1/KRT84/WNT10A/TRPC4AP/LRP4/ZDHHC21/WNT10B/APCDD1/SMO/LRIG1/NOM1/CD109	44
BP	GO:0098773	skin epidermis development	44/7096	88/18670	0.01433	0.07352	0.05481	DLL1/RBPJ/WNT5A/LGR4/LDB1/TNF/RELA/MYO5A/SOX21/FUZ/INTU/TRADD/NSUN2/GORAB/SAV1/ACVR1B/EDA/HPSE/HDAC2/EDAR/BCL2/INHBA/PDGFA/ZMPSTE24/EGFR/DNASE1L2/LGR5/ERCC2/SNAI1/TMEM79/ATP7A/KRT27/CDH3/FOXN1/KRT84/WNT10A/TRPC4AP/LRP4/ZDHHC21/WNT10B/APCDD1/SMO/NOM1/CD109	44
BP	GO:1900407	regulation of cellular response to oxidative stress	44/7096	88/18670	0.01433	0.07352	0.05481	FYN/GCH1/ATG7/PINK1/TSC1/SOD1/FBXW7/PSAP/TNF/SLC7A11/ATF4/HGF/HIF1A/HSPB1/CD36/MAPK7/MCL1/HTRA2/TLR4/NCOA7/SIRT1/SFPQ/BMP7/LRRK2/MIR34A/VNN1/MMP3/FZD1/NFE2L2/DHFR/TXN/WNT1/NR4A3/MAPKAP1/LANCL1/GPX1/PDE8A/BAG5/ABCD1/MET/ENDOG/TLR6/FOXO3/OXR1	44
BP	GO:0032653	regulation of interleukin-10 production	28/7096	52/18670	0.01449	0.07414	0.05527	NOD2/TLR2/DLL1/CLEC7A/LILRA5/TNFRSF21/LILRB1/HGF/IL20RB/TLR4/IDO1/AGER/HMGB1/TYROBP/TIGIT/PDCD1LG2/CD47/TRIB2/CD274/LGALS9/TNFSF4/TREM2/TSLP/CD34/IL12B/PRKCZ/CD83/IL23A	28
BP	GO:0048168	regulation of neuronal synaptic plasticity	28/7096	52/18670	0.01449	0.07414	0.05527	RAB11A/EPHB2/KRAS/APOE/UNC13B/HRAS/RAB3GAP1/S100B/RAB8A/NPTN/EGR2/ARC/SHISA9/RAB5A/SYNGAP1/CAMK2A/RASGRF1/NSMF/SLC8A2/RAB3A/PPFIA3/SYT4/APP/SNCA/SHISA8/SHANK3/CAMK2B/SYNPO	28
BP	GO:1900024	regulation of substrate adhesion-dependent cell spreading	28/7096	52/18670	0.01449	0.07414	0.05527	MYADM/S100A10/GBP1/NEDD9/FLNA/CIB1/ACTN4/ABL1/CRK/RAC1/DOCK5/PTK2/NRP1/DNM2/UNC13D/KANK1/TRIOBP/DMTN/CORO1C/CALR/C1QBP/RCC2/PREX1/APOA1/TACSTD2/ARPC2/LIMS1/ITGB1BP1	28
BP	GO:0051961	negative regulation of nervous system development	139/7096	315/18670	0.01451	0.07419	0.05531	RTN4R/TLR2/DPYSL3/DLL1/APPL2/ARF6/SKI/DNM3/WNT5A/DENND5A/TSC1/HMG20A/STAT3/SEMA4B/VIM/LRIG2/SPP1/DUSP10/RNF10/CIB1/ULK2/CTSC/YWHAH/CERS2/TNF/PRKACB/EPHB2/ARHGDIA/IFRD1/TNFRSF21/APOE/GSK3B/PTPRO/NOTCH3/MIB1/UBE3A/TGFB1/TULP3/DGUOK/CTNNA1/RAPGEF2/PCM1/BCL11A/NRG1/MBD1/SEMA4A/ASCL2/FIG4/DTX1/CDK5/PLK2/TRAK2/PAFAH1B1/CTSZ/CDK5RAP2/SRGAP2C/IL1B/GDI1/SEMA4C/LDLR/ARHGEF2/PAQR3/SEMA4D/LRP1/HEY1/TRIM11/BMP7/RAB29/IL6/LRRK2/DCC/IDH2/ASPM/PTK2/DICER1/DIXDC1/SEMA6B/SRGAP2/HDAC2/BMPR1A/NRP1/SEMA3B/HOOK3/ID2/CTDSP1/KCTD11/CNTN4/PRKACA/KANK1/LGALS1/SYNGAP1/MTMR2/DAB1/INPP5F/RTN4RL1/PITX3/SEMA5A/LPAR1/HES1/FSTL4/CALR/CNTF/TLX3/SLIT2/PSEN1/MDM2/SEMA5B/RTN4RL2/EIF4E/RUFY3/PLXNA3/SPOCK1/NR2F1/GPR161/CARM1/TRAF3IP1/TERT/MEIS1/EIF2AK4/NR2E1/SYT4/MAP4K4/RHOA/TRPV4/APP/RTN4/CX3CL1/BAG5/KREMEN1/ASAP1/LMX1A/FGF13/LRP4/WNT7A/EIF4ENIF1/DAAM2/FOXO3/TRIM46/MIR146A	139
BP	GO:0050810	regulation of steroid biosynthetic process	47/7096	95/18670	0.01469	0.07502	0.05593	VDR/ASAH1/POR/STARD4/SOD1/ATP1A1/NFYC/GPAM/DDX20/SQLE/EGR1/TNF/AKR1C3/NFKB1/RAN/IGFBP7/APOE/HMGCR/HMGCS1/SCD/LEP/ERLIN1/BMP2/IL1B/ERLIN2/FDPS/ACACB/SIRT1/PPARGC1A/FGF1/TM7SF2/IDI1/BMP5/SCAP/ABCG1/SC5D/SREBF2/INSIG1/PRKAA1/CYP27B1/SNAI1/IFNG/MBTPS2/ELOVL6/MBTPS1/KPNB1/NR1H4	47
BP	GO:2000060	positive regulation of ubiquitin-dependent protein catabolic process	47/7096	95/18670	0.01469	0.07502	0.05593	CBFA2T3/SMAD7/KEAP1/DDRGK1/FBXW7/RNF139/BCAP31/GSK3B/MAGEF1/RNF19B/SGTA/ZFAND2A/SOCS5/PTK2B/CSNK1D/RNF217/CEBPA/PLK2/ANKIB1/GCLC/CLU/LRRK2/SUMO1/PTK2/HSPBP1/CSNK1A1/CSNK1E/ARIH2/PLK3/DISC1/UBQLN2/TRIB2/BBS7/DET1/NKD2/KLHL40/STUB1/NFE2L2/CAV3/DVL1/PSEN1/MDM2/VCP/AURKA/RBX1/CHFR/MAPK9	47
BP	GO:1902116	negative regulation of organelle assembly	22/7096	39/18670	0.01486	0.07577	0.05649	PINK1/FEZ2/SEC22B/NUPR1/KAT2B/CHMP4B/TRIM37/MAP4/CDK5RAP2/ARHGEF2/LRRK2/PHF23/MAK/DNM2/CHMP2A/TBC1D7/BRCA1/CAV3/KAT2A/TCHP/SMCR8/SCFD1	22
BP	GO:1902229	regulation of intrinsic apoptotic signaling pathway in response to DNA damage	22/7096	39/18670	0.01486	0.07577	0.05649	TRIM32/CDKN2D/SKIL/MIF/ACKR3/CD44/CD74/CXCL12/HNRNPK/TMEM161A/CLU/SIRT1/ELL3/MUC1/NACC2/BCL2/TAF9B/SNAI1/RAD9A/TRIAP1/ATAD5/DDIAS	22
BP	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	50/7096	102/18670	0.01493	0.07605	0.05669	CTSF/CTSD/KLC1/AP1B1/DYNC1LI1/CTSS/LGMN/CD74/KIF3B/OSBPL1A/KIFAP3/SAR1B/CAPZA2/DYNLL2/TRAF6/CENPE/HLA-DPB1/HLA-DPA1/CAPZA1/KIF4A/HLA-DMB/HLA-DOB/KIF2A/HLA-DRA/AP1M2/HLA-DMA/ARF1/AP2A2/DNM2/DCTN2/LAG3/AP2S1/CTSV/CTSE/CANX/AP2A1/AP1S3/AP1G1/HLA-DQB2/KIF2C/TREM2/AP1M1/SPTBN2/DYNC1LI2/KLC2/AP2M1/DCTN6/DCTN5/SEC24A/HLA-DOA	50
BP	GO:0032233	positive regulation of actin filament bundle assembly	32/7096	61/18670	0.01503	0.07648	0.05702	S100A10/FHOD1/TSC1/SORBS3/FLNA/RHOC/RGCC/ARHGEF10L/EVL/PFN1/PAK1/SWAP70/ABL1/PPM1F/RAC1/LIMCH1/NRP1/TPM1/CD47/PLEK/LPAR1/PXN/APOA1/TGFB3/SYNPO2L/MTOR/RHOA/CX3CL1/ITGB1BP1/ROCK2/SERPINF2/SYNPO	32
BP	GO:0006901	vesicle coating	36/7096	70/18670	0.01508	0.07671	0.05719	SERPINA1/F5/MCFD2/KLHL12/CTSC/SEC22B/CD59/ANKRD28/SAR1B/TRAPPC6A/CSNK1D/PPP6R1/CNIH3/TRAPPC5/CTSZ/ARFGAP3/TMED10/BET1/GOSR2/STX5/SAR1A/PPP6C/TRAPPC6B/TRAPPC9/NAPA/TBC1D20/COL7A1/LMAN1/PEF1/SEC23IP/TRAPPC2L/TRAPPC3/SCFD1/PREB/SEC24A/SEC16B	36
BP	GO:0009267	cellular response to starvation	70/7096	149/18670	0.01536	0.07787	0.05806	PDK4/UPP1/CDKN1A/ATG7/SRD5A1/KLF10/PMAIP1/GAS2L1/SIK1/ATG14/LAMP2/FAS/HFE/AKR1C3/ATF4/WDR24/HIGD1A/XPR1/MAP1LC3A/SEH1L/HSPA5/HNRNPA1/PPM1D/SIK2/RRAGD/WIPI1/NPRL3/SIRT1/EIF2S1/KPTN/LRRK2/MAP1LC3C/FNIP1/ZFYVE1/MYBBP1A/MAPK8/BCL2/ASNS/WDR45B/CTSV/TNRC6A/SREBF2/MAP3K5/RRAGA/NFE2L2/IMPACT/EIF2AK2/DSC2/ITFG2/SESN1/PRKAA1/DNAJC15/MAPK1/MTMR3/SH3GLB1/NPRL2/DAP/TBL2/DAPL1/GABARAPL1/CLEC16A/WNT2B/EIF2AK4/CADPS2/MTOR/PICK1/DEPDC5/SESN2/ALB/BMPR2	70
BP	GO:0014074	response to purine-containing compound	70/7096	149/18670	0.01536	0.07787	0.05806	CRHBP/SLC8A1/JUNB/FOS/EZR/DUSP1/LDHA/AQP9/FOSB/SOD1/SRD5A1/RAP1B/JUND/PTGS2/BIRC2/STAT1/P2RX7/PKD2/RELA/AACS/HMGCS1/PTAFR/RAPGEF2/PTK2B/PANX1/P2RY6/RYR1/HSPA5/IL1B/RAP1A/AHR/P2RY12/THBD/TRPM4/TRPM2/PPARGC1A/SPARC/HCN4/HDAC2/P2RX1/PFKFB1/XRN1/INPP5K/NME1/KCNQ1/DMTN/FDX1/HSP90B1/PRKAA1/P2RY4/CASQ2/CAD/FOSL1/TMEM38B/PIK3CG/REN/CARM1/APP/P2RX2/CIB2/SSH1/PNPT1/HCN1/SLC8A3/WNT10B/ALDH3A1/MMP19/WT1/P2RY1/P2RX5	70
BP	GO:0001942	hair follicle development	43/7096	86/18670	0.01536	0.07787	0.05806	RBPJ/WNT5A/LGR4/LDB1/TNF/RELA/MYO5A/SOX21/FUZ/INTU/TRADD/NSUN2/GORAB/SAV1/ACVR1B/EDA/HPSE/HDAC2/EDAR/BCL2/INHBA/PDGFA/ZMPSTE24/EGFR/DNASE1L2/LGR5/ERCC2/SNAI1/TMEM79/ATP7A/KRT27/CDH3/FOXN1/KRT84/WNT10A/TRPC4AP/LRP4/ZDHHC21/WNT10B/APCDD1/SMO/NOM1/CD109	43
BP	GO:0030101	natural killer cell activation	43/7096	86/18670	0.01536	0.07787	0.05806	ELF4/CD2/PTPRC/IL15/LAMP1/TICAM1/IL21R/AXL/IL18R1/PRDX1/LEP/HLA-F/CORO1A/ZBTB1/FLT3LG/PTPN22/HLA-E/CASP8/RASGRP1/TYROBP/TOX/SNX27/BLOC1S3/PIK3CD/ID2/UNC13D/IFNK/RHBDD3/PGLYRP4/ULBP2/IL18/AP1G1/MERTK/HAVCR2/HNF1A/NCR3/IL12B/MICA/NCR1/TYRO3/CD244/RAB27A/IL23A	43
BP	GO:0034656	nucleobase-containing small molecule catabolic process	27/7096	50/18670	0.01546	0.07833	0.0584	TYMP/PNP/UPP1/AHCY/ENTPD1/HDDC3/NUDT1/NT5C/CDADC1/DPYD/NUDT9/APOBEC3G/APOBEC3C/APOBEC2/DERA/NUDT5/GALT/ADPRM/ADA/APOBEC3B/CDA/NT5C3A/ENPP4/NT5M/UPP2/ADAL/NUDT16	27
BP	GO:0007099	centriole replication	21/7096	37/18670	0.01572	0.07947	0.05925	NUP62/KAT2B/TRIM37/SASS6/PLK2/NPM1/CDK5RAP2/KIAA0753/CEP76/SPICE1/CHMP2A/CEP152/VPS4B/CEP63/BRCA1/CETN1/CETN2/KAT2A/CEP120/C2CD3/ALMS1	21
BP	GO:0030212	hyaluronan metabolic process	21/7096	37/18670	0.01572	0.07947	0.05925	HEXB/ABCC5/PIM1/CHP1/CD44/IL15/SLC9A1/NFKB1/HEXA/TGFB1/HGF/HYAL2/IL1B/PDGFB/GUSB/HYAL3/AP2A1/CEMIP/STAB2/LYVE1/ITIH3	21
BP	GO:0034405	response to fluid shear stress	21/7096	37/18670	0.01572	0.07947	0.05925	KLF4/KLF2/PTGS2/SMAD7/P2RX7/PKD2/TGFB1/SOCS5/PTK2B/MAPK7/ABCA1/CITED2/ETS1/SREBF2/NFE2L2/ADAM9/TGFB3/MAP2K5/MTSS1/GJA1/MEF2C	21
BP	GO:0097305	response to alcohol	105/7096	233/18670	0.01582	0.07985	0.05953	CRHBP/KLF4/NQO1/S100A8/FOS/KLF2/FYN/KCNMB1/PTGER4/CDKN1A/SPI1/FOSB/AIFM1/SOD1/PTGER2/STAT3/GNB1/BIRC2/RGS2/SMAD2/GSTP1/AKR1C3/IGFBP7/HMGCR/ACTR2/LRP8/CDK4/TGFB1/AACS/HMGCS1/ALAD/CTNNA1/HPGD/PTK2B/LEP/ADAM15/P2RY6/ACTC1/USP46/CAT/CASP8/ABCA1/AHR/CCL7/KLF9/RGS19/CCND1/SETD7/ADCY7/GNG2/G6PD/CCR5/ADCY1/SPARC/MLC1/OXCT1/HDAC2/AKAP8/XRN1/ADCY3/MAP4K1/SETDB1/INHBA/TYMS/CYBA/CYBB/HNRNPD/GOT2/NPAS4/FDX1/NFE2L1/BRCA1/DNMT3A/SLIT2/MAOB/TNFSF4/PRKAA1/HAMP/CHRNB2/P2RY4/BAD/CAD/FOSL1/CLDN18/DBH/POLB/ND4/RHOA/DAG1/CCL19/BAK1/MGMT/CCR7/LANCL2/SMO/ADH7/ADCYAP1R1/SPIDR/UCN3/RBP4/HTR3A/PTCH1/FOXO3/RPL10A/SLIT3	105
BP	GO:0032543	mitochondrial translation	64/7096	135/18670	0.01582	0.07985	0.05953	MRPS6/ALKBH1/MRPL35/MRPL45/UQCC1/CHCHD1/MRPL40/MTIF2/MRPS30/MRPL34/LARS2/MRPS16/UQCC2/MRPS14/MRPL54/MRPL44/MRPL33/IARS2/SHMT2/MRPL51/OXA1L/GFM2/MTRF1L/MRPL49/MRPL3/NOA1/MRPL42/DAP3/COA3/C1QBP/MRPS34/NGRN/MRPL4/GADD45GIP1/MRPS33/MTIF3/RPUSD3/MRPL20/MRPL46/MRPS18B/MRPL24/MRPL36/MRPS25/YARS2/DARS2/MRPS15/QRSL1/MRPL48/MTRF1/AURKAIP1/MRPL41/MRPL2/TRMT10C/GFM1/MPV17L2/MRPS2/MRPS9/AARS2/NDUFA7/WARS2/MRPL30/MRPL1/MRRF/MRPS17	64
BP	GO:0001836	release of cytochrome c from mitochondria	31/7096	59/18670	0.01609	0.08105	0.06043	IGF1/BMF/PINK1/LMNA/PMAIP1/PRELID1/GGCT/HIGD1A/HGF/FIS1/FZD9/SFN/TNFSF10/CHCHD10/CLU/PLAUR/PDCD5/BCL2L11/MMP9/BCL2/BAX/MLLT11/DNM1L/BAD/PLA2G6/MOAP1/WDR35/GPX1/TRIAP1/TIMM50/BAK1	31
BP	GO:0046847	filopodium assembly	31/7096	59/18670	0.01609	0.08105	0.06043	EZR/DPYSL3/ARF6/DNM3/ARAP1/SPATA13/FGD6/FGD5/PRKCD/SRF/SRGAP2C/PPP1R16B/TRPM2/SRGAP2/NRP1/BCAS3/RHOQ/RAB5A/DMTN/DOCK11/FSCN1/FMR1/MYO10/TGFB3/FGD3/MIEN1/FGD4/ARHGEF4/CCR7/TENM2/ZMYND8	31
BP	GO:0030218	erythrocyte differentiation	55/7096	114/18670	0.01616	0.08132	0.06062	EPAS1/KLF2/SPI1/LYN/ZFP36/JMJD6/STAT3/PTPN2/LYAR/THRA/BCL6/SMAD5/CEBPG/STAT1/JAK2/LDB1/TMOD3/HCLS1/FAM210B/ZBTB7A/HIF1A/SRF/VEGFA/CASP3/TMEM14C/ISG15/MFHAS1/KLF13/ACVR1B/G6PD/TAL1/ETS1/IKZF1/RPS19/KMT2E/BMP4/HMGB2/ID2/SFXN1/INHBA/DMTN/ARNT/DYRK3/NFE2L1/ERCC2/SLC4A1/EPB42/RB1/INHA/SLC25A38/ADAR/TRIM58/PRMT1/DNASE2/FOXO3	55
BP	GO:0071230	cellular response to amino acid stimulus	35/7096	68/18670	0.01617	0.08132	0.06062	FYN/GCLM/CAPN2/CEBPB/TNF/SH3BP4/BCL11A/BAIAP2/PDGFC/KLHL22/GCLC/LAMTOR1/RRAGD/LAMTOR4/CPEB1/CYBA/CYBB/HNRNPD/CPEB3/RRAGA/LAMTOR5/NSMF/EGFR/AMIGO1/SESN1/DNMT3A/UBR1/SOCS1/ATP7A/MMP2/MTOR/SESN2/SLC38A9/PDGFD/NTRK2	35
BP	GO:0043524	negative regulation of neuron apoptotic process	69/7096	147/18670	0.01638	0.08235	0.06139	FYN/CX3CR1/GRN/NR4A2/PINK1/GCLM/SOD1/ALKBH1/LGMN/CEBPB/JAK2/ADAM8/HMOX1/KRAS/APOE/BTG2/AXL/STXBP1/ARRB1/HIF1A/WFS1/PTK2B/CORO1A/ITSN1/FZD9/HRAS/NMNAT1/GCLC/ZPR1/CLN3/MAP3K12/LRP1/PPARGC1A/SNX6/NRP1/BCL2/KDM2B/BAX/CLCF1/SYNGAP1/UNC5B/LIG4/BHLHB9/F2R/CNTF/PSEN1/CNTFR/STAMBP/MAP2K4/TGFB3/FAIM2/NR4A3/HYOU1/PIN1/HSP90AB1/SET/TERT/RHOA/TYRO3/SNCA/CX3CL1/PTPRZ1/SLC30A10/ERBB3/KIF14/NTRK2/MEF2C/OXR1/GDF5	69
BP	GO:0002279	mast cell activation involved in immune response	26/7096	48/18670	0.0165	0.08282	0.06175	RAC2/LYN/IL4R/HMOX1/C12orf4/STXBP1/LAT2/STXBP2/FGR/RASGRP1/S100A13/PLA2G3/ADORA2B/PIK3CD/UNC13D/CD300A/LGALS9/FER/RABGEF1/IL13RA2/CD84/NR4A3/PIK3CG/SNX4/FOXF1/LAT	26
BP	GO:0046850	regulation of bone remodeling	26/7096	48/18670	0.0165	0.08282	0.06175	SIGLEC15/PDK4/CSK/ATP6AP1/SPP1/TNFAIP3/S1PR1/P2RX7/ADAM8/LEP/LTBP3/TNFRSF11A/PLEKHM1/IL6/TMEM64/SUCO/EGFR/TFRC/DCSTAMP/CLDN18/CSF1R/IAPP/TMEM119/GJA1/GREM1/PRKCA	26
BP	GO:0006369	termination of RNA polymerase II transcription	20/7096	35/18670	0.01661	0.08304	0.06191	PCF11/LSM11/CSTF3/SNRPB/SYMPK/CPSF3/CLP1/PAPOLA/SCAF8/SETX/FIP1L1/SNRPF/CSTF1/SCAF4/MAZ/CPSF2/CPSF1/CPSF7/SNRPG/ZNF473	20
BP	GO:0021955	central nervous system neuron axonogenesis	20/7096	35/18670	0.01661	0.08304	0.06191	NR4A2/TCTN1/EPHB2/ZEB2/SCN1B/B4GALT6/FBXO45/ADARB1/PAFAH1B1/DCC/MYCBP2/TSKU/PTK2/NDEL1/B4GALT5/SLIT2/CHRNB2/EPHB1/HSP90AB1/NR2E1	20
BP	GO:0045622	regulation of T-helper cell differentiation	20/7096	35/18670	0.01661	0.08304	0.06191	NFKBIZ/ANXA1/BCL6/NLRP3/SMAD7/IL4R/SOCS5/ZBTB7B/NFKBID/IL12RB1/HLX/IL18/TNFSF4/IL12B/PRKCZ/CD80/TBX21/CCL19/MALT1/IL23A	20
BP	GO:1902991	regulation of amyloid precursor protein catabolic process	20/7096	35/18670	0.01661	0.08304	0.06191	IGF1/LYN/TNF/APOE/CASP3/TMED10/AGER/CLU/FLOT2/ABCG1/ABCA7/IFNGR1/IFNG/PIN1/APP/GSAP/PICALM/ROCK2/BIN1/EFNA3	20
BP	GO:2000785	regulation of autophagosome assembly	20/7096	35/18670	0.01661	0.08304	0.06191	PINK1/C9orf72/FEZ2/SEC22B/NUPR1/CHMP4B/RAB3GAP1/NPRL3/LRRK2/PHF23/UBQLN2/RAB5A/ULK1/MTMR3/SH3GLB1/IFT20/SMCR8/NPRL2/SCFD1/RNF5	20
BP	GO:0071248	cellular response to metal ion	87/7096	190/18670	0.01664	0.08312	0.06197	CRHBP/NQO1/JUNB/SLC40A1/FOS/ALOX5AP/MEF2A/FBP1/FABP4/FOSB/WNT5A/SOD1/MCOLN1/SYT11/JUND/RASGRP2/PTGS2/LGMN/HFE/HMOX1/AKR1C3/PKD2/ATF4/ALAD/ZNF658/MAP1LC3A/CPNE8/NCF1/RYR1/CEBPA/HSPA5/CREB1/TRPM2/EIF2S1/ADCY7/LRRK2/PPARGC1A/SYT6/CLIC4/SUMO1/ADCY1/XRCC4/HVCN1/MYOG/CYP1A2/MAPK8/MMP9/FUS/ID2/CDKN1B/CYBB/LIG4/DMTN/CALR/SLC41A1/CACYBP/NFE2L2/NFE2L1/CAMK2D/EGFR/TPH2/SYT13/CPNE1/PRKAA1/MAPK1/SYT9/RASAL1/CAPN3/ATP7A/CHP2/CPNE3/SLC25A24/SYT1/CPNE9/SYT2/SYT4/SYT5/CPNE2/APP/SNCA/SLC30A10/CHUK/ENDOG/CACNA1H/DAXX/MEF2C/MAPK9	87
BP	GO:0006605	protein targeting	186/7096	432/18670	0.0168	0.08385	0.06251	ITGAM/FYN/RAC2/PINK1/ATG3/ZDHHC20/TIMM23B/IMMP1L/UQCRC2/NCOA4/CHP1/HPS4/HMGCL/PEX12/ACAA1/SIRT4/CIB1/FBXW7/MIPEP/LAMP2/PHYH/GDAP1/C2CD5/SCP2/MPV17/VPS37B/PEX16/VPS13A/M6PR/CHMP4B/CSNK2A2/CDC37/ZDHHC9/SEC62/MIEF1/SGTA/ARL6IP1/FIS1/PAK1/SEC61B/ECH1/NAGPA/UBE2D3/MICALL1/GNPTAB/SSR1/NCF1/HTRA2/UBE2D2/HSPA5/USP9X/DNAJC19/CDK5/CAT/HRAS/TRAK2/TIMM8B/AGPS/GDI1/HOMER3/PMM2/ZDHHC6/TIMM17A/VPS37C/ACOX1/SDCBP/ECI2/RPL8/SLC27A2/HSD17B4/ATG13/IDH1/ACOX2/CLU/TIMM21/GRPEL1/RPS24/GOSR2/AP1M2/LRRK2/DAO/DECR2/MYO1C/RHOU/MLYCD/PDCD5/TIMM10B/RPS21/IMMP2L/RPS9/GRPEL2/RPS19/ARIH2/VPS13D/ABLIM3/NEDD4/INPP5K/TOMM22/MICALL2/AP4S1/TOMM40L/NUDT19/PEX13/HGS/TYSND1/PEX3/UBL4B/UBC/PEX19/TOMM40/EHHADH/SPCS2/SRP14/LMAN1/VTI1A/SRP72/YWHAQ/SREBF2/RABGEF1/FZD5/DMTN/TOMM20/HSPA1L/AP4B1/SRP68/RTP4/CEMIP/RAB8B/NUDT7/TIMM22/PEX14/AP1S3/PITRM1/ZDHHC14/AP3B1/AGK/HSPA4/PRKAA1/DNAJC15/SEC61G/PARL/ZDHHC2/SH3GLB1/YWHAE/VTI1B/ICMT/ACOX3/KATNB1/RPL24/ZDHHC18/UBL5/EXOC4/RPS16/RPS12/GNPAT/BAP1/AP3M1/TRAK1/TOMM5/PMPCB/CACNB3/YWHAG/RPL32/CROT/CHM/ITGB1BP1/ZDHHC12/ZFAND6/TIMM50/SEC61A2/ZDHHC21/SNX16/HACL1/STXBP4/TOMM34/TRAM1/MGARP/RAB27A/TIMM44/OS9/HAO1/TIMM9/ACOT8/PIPOX/RPL10A/AIP	186
BP	GO:0002200	somatic diversification of immune receptors	38/7096	75/18670	0.01703	0.08486	0.06327	IL27RA/MAD2L2/STAT6/BCL6/CD40/PTPRC/BATF/TGFB1/UNG/SWAP70/SAMHD1/HMGB1/ATM/PMS2P5/XRCC4/MLH1/PARP3/HMGB2/ERCC1/CLCF1/CCR6/LIG4/POLL/BCL11B/TFRC/TNFSF4/EXO1/PMS2P3/DCLRE1C/EXOSC3/MCM3AP/POLB/TBX21/APLF/EXOSC6/ADAR/PAXIP1/ATAD5	38
BP	GO:0015914	phospholipid transport	38/7096	75/18670	0.01703	0.08486	0.06327	KCNN4/ATP8B2/ATP8A1/NPC2/PITPNA/APOC1/SCARB1/P2RX7/SCP2/CETP/APOE/PRELID1/STARD10/PITPNM1/PRKCD/ATP11B/ATP10A/ABCA1/LDLR/C2CD2L/ATP8B1/STARD7/APOA5/MFSD2A/PLEKHA8/ABCG1/OSBPL2/ABCB4/CPTP/ABCA7/PRELID2/PLEKHA3/APOA1/TMEM30A/TRIAP1/GLTP/PLEKHA8P1/ATP10B	38
BP	GO:0006885	regulation of pH	48/7096	98/18670	0.01713	0.08527	0.06357	ATP6V0D2/PDK4/GRN/SLC11A1/SLC9A9/ATP6AP1/DMXL1/CHP1/ATP6V1C1/ATP6V0C/SLC9A1/AQP11/PDK2/TCIRG1/CLCN3/ATP6V1A/CLN3/VPS33A/RAB20/ATP6V1G3/ATP6V1B2/SLC9A8/LRRK2/RAB38/SLC9A7/ATP6V1D/ROGDI/ATP6AP1L/MAFG/BCL2/ATP6V0E2/CLN6/CLN5/SLC4A5/ATP6V1G2/SLC26A4/MAPK1/SLC4A7/SLC4A1/ATP6V1B1/CCKBR/TM9SF4/SLC4A11/SLC9C2/ATP12A/SLAMF8/SLC4A3/DMXL2	48
BP	GO:0000187	activation of MAPK activity	71/7096	152/18670	0.01714	0.08527	0.06357	IGF1/NOD2/FPR1/PEA15/DUSP6/WNT5A/DUSP5/SOD1/ERP29/MAP2K1/DUSP7/PTPRC/P2RX7/ALK/UBE2N/TNF/CD74/ERCC6/MAPKAPK3/HGF/ARRB1/MAP4K5/INSR/TAB3/NRG1/TRAF6/IKBKG/TLR4/BMP2/IL1B/CSPG4/MAP3K12/MDFIC/SHC1/PDE6G/MAP4K2/LRRK2/FGF1/PROK1/MAPKAPK5/TAB1/ADORA2B/MAPKAPK2/MAP3K6/MAP4K1/LPAR3/MLKL/UBC/MAP2K2/MAP3K11/BIRC7/LPAR1/MAP3K5/PROK2/MOS/MUL1/PRKAA1/MAPK1/MAP2K4/TGFB3/MAP3K13/MAPK11/RET/MAP2K5/ERN1/CCL19/GHR/DAXX/GHRL/PIK3CB/MAP3K9	71
BP	GO:0045981	positive regulation of nucleotide metabolic process	30/7096	57/18670	0.01722	0.08532	0.06361	IGF1/PINK1/PGK1/STAT3/PFKFB3/P2RX7/NUPR1/HIF1A/ISCU/INSR/ENO1/PFKFB4/PPARGC1A/SLC25A12/MYOG/ADORA2B/PFKFB1/PGK2/PFKFB2/ARNT/PRKAA1/PSEN1/PID1/TREM2/IFNG/ESRRB/ZBTB20/VCP/TAZ/APP	30
BP	GO:0051055	negative regulation of lipid biosynthetic process	30/7096	57/18670	0.01722	0.08532	0.06361	SLC27A1/SOD1/ATP1A1/FBXW7/SIK1/APOC1/AKR1C3/NFKB1/APOE/ENHO/ERLIN1/BMP2/ERLIN2/SIRT1/PDGFB/ORMDL2/SPHK1/BMP5/ORMDL3/SCAP/PDGFA/ACADVL/SERPINA12/INSIG1/BRCA1/PRKAA1/CYP27B1/SNAI1/LPCAT1/NR1H4	30
BP	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	30/7096	57/18670	0.01722	0.08532	0.06361	ENY2/HMGCR/LRP5/PPP3CB/ARRB1/HIF1A/PIM3/C2CD2L/MPC2/LRP1/TRPM4/RAC1/KLF7/SRI/OXCT1/GPR27/PDX1/HMGN3/BAD/PLA2G6/KIF5B/NDUFAF2/MAP4K4/SLC9B2/SIDT2/GCG/NR1H4/STXBP4/GHRL/PHPT1	30
BP	GO:0072431	signal transduction involved in mitotic G1 DNA damage checkpoint	30/7096	57/18670	0.01722	0.08532	0.06361	CDKN1A/RGCC/BTG2/PLK2/SFN/PML/ATM/TNKS1BP1/MUC1/PLK3/PCNA/BAX/CRADD/CASP2/CDKN1B/CNOT4/PLAGL1/ARID3A/E2F4/CNOT7/GML/MDM2/RBL2/CNOT10/CARM1/TRIAP1/AURKA/SOX4/PRMT1/E2F8	30
BP	GO:1900544	positive regulation of purine nucleotide metabolic process	30/7096	57/18670	0.01722	0.08532	0.06361	IGF1/PINK1/PGK1/STAT3/PFKFB3/P2RX7/NUPR1/HIF1A/ISCU/INSR/ENO1/PFKFB4/PPARGC1A/SLC25A12/MYOG/ADORA2B/PFKFB1/PGK2/PFKFB2/ARNT/PRKAA1/PSEN1/PID1/TREM2/IFNG/ESRRB/ZBTB20/VCP/TAZ/APP	30
BP	GO:1902400	intracellular signal transduction involved in G1 DNA damage checkpoint	30/7096	57/18670	0.01722	0.08532	0.06361	CDKN1A/RGCC/BTG2/PLK2/SFN/PML/ATM/TNKS1BP1/MUC1/PLK3/PCNA/BAX/CRADD/CASP2/CDKN1B/CNOT4/PLAGL1/ARID3A/E2F4/CNOT7/GML/MDM2/RBL2/CNOT10/CARM1/TRIAP1/AURKA/SOX4/PRMT1/E2F8	30
BP	GO:0007009	plasma membrane organization	51/7096	105/18670	0.01726	0.08537	0.06364	MYOF/MPP5/SOD1/SYT11/PLSCR1/FCHO1/PACSIN2/FCHO2/FLOT1/PTPRC/PSAP/P2RX7/PLEKHM2/PRKCD/MICALL1/BAIAP2/CLU/NDRG1/SPTBN1/SNX33/ARV1/BIN2/SERP1/MYH9/XKR8/ANXA6/DNM2/SYTL4/SH3TC2/OSBPL2/UGCG/ABCA7/ANO4/CAV3/BIN3/ATP2A2/DMKN/RAB3A/SH3GLB1/SYPL2/SLC4A1/SPTA1/TMEFF2/PLSCR4/SNX9/ABCD1/MTSS1/ASAP1/BIN1/PACSIN3/PLSCR2	51
BP	GO:0032006	regulation of TOR signaling	51/7096	105/18670	0.01726	0.08537	0.06364	TSC1/C9orf72/SIK1/SH3BP4/WDR24/HIF1A/TNFAIP8L1/SEH1L/LEP/KLHL22/LAMTOR1/SIK2/ARAF/RRAGD/NPRL3/SIRT1/TBCK/KPTN/MLST8/FLCN/ATM/TMEM127/MAPKAPK5/FNIP1/LAMTOR4/EPM2A/AKT1S1/TBC1D7/RFFL/DDIT4/RRAGA/ZMPSTE24/LAMTOR5/DYRK3/ITFG2/SESN1/DEPTOR/PRKAA1/TELO2/UBR1/SMCR8/NPRL2/TREM2/ARNTL/PKHD1/CLEC16A/RELN/DEPDC5/SESN2/TTI1/SLC38A9	51
BP	GO:0040014	regulation of multicellular organism growth	34/7096	66/18670	0.01733	0.08557	0.0638	IGF1/EZR/PLS1/SOD1/STAT3/PLAC8/LGMN/CDK4/SGPL1/HTRA2/ADRB1/STAT5A/ATRN/CREB1/BBS2/AFG3L2/MKKS/MBD5/BBS4/FTO/BCL2/GPR21/ADRB2/GAMT/ZMPSTE24/APP/GHRH/GHR/PPIB/SOCS2/SMO/PTCH1/GHRL/GDF5	34
BP	GO:0046626	regulation of insulin receptor signaling pathway	34/7096	66/18670	0.01733	0.08557	0.0638	SOCS3/TSC1/PTPN2/CCND3/ADIPOR1/CISH/GKAP1/RELA/CDK4/PAK1/ENHO/LEP/PRKCD/ZBTB7B/NCK1/IL1B/SIK2/SIRT1/GRB10/GNAI2/INPP5K/GPR21/KANK1/SERPINA12/PRKAA1/PID1/SOCS1/OGT/SLA2/PRKCZ/PRKCQ/SOCS2/NUCKS1/NR1H4	34
BP	GO:0033028	myeloid cell apoptotic process	19/7096	33/18670	0.01752	0.08625	0.0643	NOD2/CLEC5A/ANXA1/ARF6/IRF7/THRA/KITLG/MIF/SLC7A11/CCL5/SIRT1/IL6/CCR5/BCL2/PIK3CD/CXCR2/ADAM17/MEF2C/PIK3CB	19
BP	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	19/7096	33/18670	0.01752	0.08625	0.0643	PPP3CB/ARRB1/HIF1A/C2CD2L/MPC2/LRP1/TRPM4/RAC1/SRI/OXCT1/GPR27/PDX1/BAD/PLA2G6/KIF5B/GCG/NR1H4/GHRL/PHPT1	19
BP	GO:0040001	establishment of mitotic spindle localization	19/7096	33/18670	0.01752	0.08625	0.0643	SPDL1/UBXN2B/PAFAH1B1/CDK5RAP2/SAPCD2/NSFL1C/ARHGEF2/ESPL1/BCCIP/NDC80/NDEL1/NUSAP1/ZW10/SPRY1/GPSM2/SPRY2/CENPA/MISP/KPNB1	19
BP	GO:0051194	positive regulation of cofactor metabolic process	19/7096	33/18670	0.01752	0.08625	0.0643	IGF1/PFKFB3/P2RX7/HIF1A/INSR/PFKFB4/PFKFB1/PFKFB2/ARNT/NFE2L2/PRKAA1/PSEN1/IFNG/DUOXA1/ESRRB/ZBTB20/APP/SNCA/NNT	19
BP	GO:0030810	positive regulation of nucleotide biosynthetic process	25/7096	46/18670	0.01761	0.08643	0.06443	IGF1/PINK1/STAT3/PFKFB3/P2RX7/HIF1A/INSR/ENO1/PFKFB4/PPARGC1A/SLC25A12/ADORA2B/PFKFB1/PFKFB2/ARNT/PRKAA1/PSEN1/PID1/TREM2/IFNG/ESRRB/ZBTB20/VCP/TAZ/APP	25
BP	GO:0033628	regulation of cell adhesion mediated by integrin	25/7096	46/18670	0.01761	0.08643	0.06443	PTPN6/LYN/LPXN/CIB1/TESC/DPP4/CYP1B1/SWAP70/CXCL13/CCL5/P2RY12/CRK/EPHA8/PTK2/MUC1/SERPINE1/ADA/ADAM9/SKAP1/HRG/RET/PIK3CG/ITGB1BP1/IFT74/CD3E	25
BP	GO:0043631	RNA polyadenylation	25/7096	46/18670	0.01761	0.08643	0.06443	PCF11/ZC3H14/PAF1/CSTF3/SYMPK/CPSF3/CDK9/CLP1/PAPOLA/SCAF8/MTPAP/SNRPA/FIP1L1/CPEB1/CPEB3/LEO1/RNF20/AHCYL1/CPSF2/CCNT1/APP/CDC73/CPSF1/PNPT1/CPSF7	25
BP	GO:1900373	positive regulation of purine nucleotide biosynthetic process	25/7096	46/18670	0.01761	0.08643	0.06443	IGF1/PINK1/STAT3/PFKFB3/P2RX7/HIF1A/INSR/ENO1/PFKFB4/PPARGC1A/SLC25A12/ADORA2B/PFKFB1/PFKFB2/ARNT/PRKAA1/PSEN1/PID1/TREM2/IFNG/ESRRB/ZBTB20/VCP/TAZ/APP	25
BP	GO:0001764	neuron migration	73/7096	157/18670	0.01787	0.08757	0.06528	FYN/NR4A2/STAT3/LRIG2/SH3RF1/FLNA/ALKBH1/POMGNT2/PLAA/CXCL12/PLXNB2/AXL/RAPGEF2/PHACTR1/PCM1/SRF/NRG1/FBXO45/VEGFA/USP9X/CDK5/PAFAH1B1/SRGAP2C/SATB2/ARHGEF2/MARK1/CRK/RAC1/DCC/ZNF609/MDGA1/ASPM/PTK2/ARX/BBS4/SRGAP2/NRP1/DISC1/ELP3/BAX/NRP2/GFRA3/MARK2/KIF20B/TOP2B/PEX13/NDEL1/DAB1/CCR4/DDIT4/ITGA3/CAMK2A/CDK5R2/UNK/NSMF/TLX3/PSEN1/DNER/YWHAE/LRP12/SPOCK1/ULK4/ACAP3/RELN/CX3CL1/FGF13/GJA1/LHX6/NTRK2/MEF2C/TRIM46/CAMK2B/CCKAR	73
BP	GO:0031570	DNA integrity checkpoint	73/7096	157/18670	0.01787	0.08757	0.06528	PEA15/CDKN1A/FBXO6/RNASEH2B/RGCC/HUS1B/GIGYF2/BTG2/DOT1L/RAD1/TAOK3/ZNF830/FEM1B/ETAA1/USP28/UIMC1/INTS7/SYF2/SETMAR/PLK2/SFN/DONSON/PML/TIPIN/CCND1/RHNO1/ATM/TNKS1BP1/MUC1/PLK3/RAD17/PCNA/BAX/CRADD/CASP2/RFWD3/CDKN1B/TOP2B/CNOT4/PLAGL1/ARID3A/TIMELESS/FOXO4/TICRR/THOC5/DTL/CEP63/FBXO4/E2F4/BRCA1/CNOT7/GML/ATR/CLOCK/MDM2/CLSPN/RBL2/RAD9A/TOPBP1/CNOT10/PRPF19/CARM1/EIF2AK4/HINFP/TRIAP1/AURKA/BRSK1/SOX4/BRCC3/WDR76/PRMT1/E2F8/TOP2A	73
BP	GO:0043624	cellular protein complex disassembly	98/7096	217/18670	0.01797	0.08801	0.06561	STMN1/MAP1S/MRPS6/CIB1/C12orf65/MICAL1/MRPL35/TMOD3/LIMA1/MRPL45/TWF2/RDX/CHCHD1/CFL2/CAPZA2/SYNJ1/SWAP70/MRPL40/MRPS30/MRPL34/STMN3/CAPG/MICAL2/TRMT112/MRPS16/ARHGEF2/CAPZA1/MRPS14/MRPL54/SH3BP1/MRPL44/SPTBN1/KIF2A/MRPL33/GSPT2/DNAJC6/SH3GL1/NAPA/AVIL/MRPL51/KIF24/CFL1/OXA1L/CKAP5/TRIOBP/GFM2/ETF1/ADD3/MTRF1L/PLEK/MRPL49/MRPL3/VPS4B/SEMA5A/DMTN/MRPL42/DAP3/CLASP2/LMOD3/PEX14/EIF5A/MRPS34/SCIN/MAP1A/MRPL4/GADD45GIP1/APEH/MRPS33/KIF2C/KATNB1/MRPL20/MRPL46/MRPS18B/SPTA1/MRPL24/MRPL36/MRPS25/SPTBN2/MRPS15/JMJD4/MRPL48/MTRF1/AURKAIP1/NAV3/TRPV4/MRPL41/NCKAP5L/TTBK2/MRPL2/SLN/MRPS2/MRPS9/FGF13/MRPL30/UPF1/MRPL1/MRRF/MRPS17	98
BP	GO:0097306	cellular response to alcohol	44/7096	89/18670	0.01809	0.0885	0.06598	KLF4/KLF2/KCNMB1/PTGER4/SPI1/AIFM1/PTGER2/GNB1/AKR1C3/LRP8/CDK4/AACS/HMGCS1/CTNNA1/ADAM15/P2RY6/ABCA1/AHR/CCL7/KLF9/ADCY7/GNG2/ADCY1/MLC1/AKAP8/XRN1/ADCY3/MAP4K1/INHBA/CYBB/NPAS4/FDX1/NFE2L1/BRCA1/DNMT3A/TNFSF4/PRKAA1/P2RY4/DAG1/LANCL2/SMO/SPIDR/PTCH1/FOXO3	44
BP	GO:0008637	apoptotic mitochondrial changes	59/7096	124/18670	0.01827	0.08926	0.06654	IGF1/BMF/PINK1/GCLM/ATG3/LMNA/SLC35F6/BLOC1S2/PMAIP1/YWHAH/AIFM2/TMEM14A/GSK3B/PRELID1/GGCT/HIGD1A/HGF/FIS1/MPV17L/FZD9/SFN/TNFSF10/GCLC/CASP8/IFIT2/RHOT2/CHCHD10/CLU/SLC25A5/PLAUR/PDCD5/BCL2L11/MAPK8/MMP9/TMEM102/BCL2/BAX/GZMB/THEM4/MLLT11/YWHAQ/CAMK2A/DNM1L/NDUFS1/MUL1/ACAA2/YWHAE/BAD/PLA2G6/PPP1R13B/NAIF1/MOAP1/WDR35/YWHAG/GPX1/TRIAP1/PIM2/TIMM50/BAK1	59
BP	GO:0019751	polyol metabolic process	59/7096	124/18670	0.01827	0.08926	0.06654	MYOF/ASAH1/GCH1/SLC5A3/CYP27A1/AKR1B1/GK/IMPAD1/PCBD1/INPP1/GALK1/TPI1/PTAFR/IP6K1/PTK2B/PCK2/LEP/SYNJ1/P2RY6/SGPP2/SPTLC2/PLCG2/PPIP5K2/QDPR/COQ3/SYNJ2/DGAT2/PTS/OCRL/SPR/SPHK1/NUDT3/PLCL1/GK5/INPP5K/IMPA2/MTMR2/PLEK/SORD/PLCD1/PLCB1/DHFR/PLD4/IPPK/PLCD4/ACER3/CYP27B1/MINPP1/PLCL2/PCBD2/SNCA/CD244/INPPL1/ADCYAP1R1/P2RY1/NTSR1/INPP5A/DEGS2/IMPA1	59
BP	GO:0019217	regulation of fatty acid metabolic process	47/7096	96/18670	0.01835	0.08944	0.06668	PDK4/ANXA1/APPL2/PTGS2/ADIPOR1/SIRT4/PANK2/SLC45A3/APOC1/CD74/ELOVL5/LPGAT1/PDK2/EIF6/NR1H2/ERLIN1/GSTZ1/IL1B/ERLIN2/ACACB/SIRT1/DGAT2/FABP3/IRS2/PPARGC1A/MLYCD/APOA5/PRKAG2/SCAP/NR1H3/PDK1/TYSND1/CPT1A/ACADVL/NFE2L1/INSIG1/PDP2/FABP5/BRCA1/PPARA/ADIPOR2/NR4A3/PDP1/MTOR/SNCA/ABCD1/PDPR	47
BP	GO:0090277	positive regulation of peptide hormone secretion	47/7096	96/18670	0.01835	0.08944	0.06668	PPARD/JAK2/HFE/PPP3CB/AACS/ARRB1/HIF1A/MCU/AIMP1/ITSN1/C2CD2L/MPC2/LRP1/TRPM4/DOC2B/RAC1/GLUD1/IRS2/SERP1/SRI/OXCT1/RPH3AL/GPR27/PDX1/TM7SF3/PFKFB2/RAB8B/EGFR/GIPR/TCF7L2/BAD/PLA2G6/KIF5B/GHRH/SOX4/GCG/NLGN2/GJA1/NR1H4/TARDBP/UCN3/RBP4/PSMD9/GHRL/KISS1/APLN/PHPT1	47
BP	GO:1905037	autophagosome organization	47/7096	96/18670	0.01835	0.08944	0.06668	ATG7/PINK1/ATG3/C9orf72/FEZ2/ULK2/ATG14/SEC22B/NUPR1/CHMP4B/RAB23/MAP1LC3A/ATG101/TP53INP2/UBXN2B/TMEM41B/RAB3GAP1/NSFL1C/ATG13/WIPI1/NPRL3/RAB33B/LRRK2/MAP1LC3C/ATG9A/PHF23/UBQLN2/ATG4B/PACS2/RAB5A/ATG2B/WDR45B/ULK1/PSEN1/MTMR3/STX12/SH3GLB1/IFT20/SMCR8/NPRL2/ATG16L2/GABARAPL1/SCFD1/RNF5/ATG4A/TRAPPC8/ATG12	47
BP	GO:1901605	alpha-amino acid metabolic process	100/7096	222/18670	0.0184	0.08944	0.06668	SMS/ASRGL1/ATP2B4/SEPHS2/GCLM/HIBADH/ARG2/IL4I1/HMGCL/ADI1/SIRT4/PSPH/AHCY/MTR/ALDH7A1/PHYKPL/SEPSECS/SLC7A11/ALDH6A1/PCBD1/HAL/DDAH2/HNMT/FAH/ALDH18A1/GMPS/SLC7A7/CRTAP/APIP/AUH/NAGS/EGLN1/CTPS2/MTRR/IDO1/GCLC/ENOPH1/GSTZ1/ODC1/QDPR/OGDH/GATM/ALDH4A1/ASNSD1/GLUD1/PLOD1/DAO/EGLN3/ADHFE1/ALDH5A1/MCCC1/KYNU/HAAO/MTAP/SLC25A12/SHMT2/GLUD2/TST/SERINC3/MPST/ALDH8A1/CTH/ASNS/BHMT/PLOD2/GAMT/PPAT/AZIN1/GLS/GOT2/AHCYL2/AGXT2/SHMT1/AHCYL1/DCT/AASDHPPT/IDO2/AMT/GFPT1/SRR/FPGS/CTPS1/CAD/AMDHD1/ATP7A/BCAT2/GFPT2/HYKK/SLC25A32/AZIN2/ATCAY/AGMAT/HMGCLL1/PHGDH/P4HA1/TDO2/NR1H4/MAT1A/CKMT2/PIPOX	100
BP	GO:0010165	response to X-ray	18/7096	31/18670	0.01844	0.08944	0.06668	ANXA1/CDKN1A/ERCC6/CASP3/XRCC5/IKBIP/THBD/CCND1/ATM/XRCC4/DNM2/ERCC1/LIG4/HAMP/XRCC6/BRCC3/NUCKS1/ERCC8	18
BP	GO:0031338	regulation of vesicle fusion	18/7096	31/18670	0.01844	0.08944	0.06668	ANXA1/C2CD5/VPS41/STXBP1/CORO1A/ANKRD27/DOC2B/SPHK1/VPS18/ANXA2P2/RAB3A/SYT9/SYT1/KIF5B/VPS16/VAMP1/SYT4/ANXA2	18
BP	GO:0043304	regulation of mast cell degranulation	18/7096	31/18670	0.01844	0.08944	0.06668	RAC2/LYN/IL4R/HMOX1/C12orf4/STXBP1/STXBP2/FGR/ADORA2B/UNC13D/CD300A/LGALS9/FER/RABGEF1/IL13RA2/CD84/SNX4/FOXF1	18
BP	GO:0050849	negative regulation of calcium-mediated signaling	18/7096	31/18670	0.01844	0.08944	0.06668	ATP2B4/CHP1/PKD2/GSK3B/CD22/DYRK2/ITPR1/MAPK7/GSTO1/HOMER3/SRI/RCAN1/PLEK/MYOZ1/FHL2/CASQ2/SLA2/MTOR	18
BP	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	18/7096	31/18670	0.01844	0.08944	0.06668	TRIM32/CDKN2D/MIF/ACKR3/CD44/CD74/CXCL12/TMEM161A/CLU/SIRT1/ELL3/MUC1/BCL2/TAF9B/SNAI1/TRIAP1/ATAD5/DDIAS	18
BP	GO:0043030	regulation of macrophage activation	29/7096	55/18670	0.01844	0.08944	0.06668	GRN/TNIP2/WNT5A/MIF/CTSC/IL4R/PTPRC/CD74/MIR142/TLR4/CEBPA/LDLR/MFHAS1/TTBK1/IL6/LRRK2/CST7/ATM/VSIG4/SPHK1/NR1H3/TREM2/RORA/HAVCR2/SLC7A2/LBP/SNCA/CX3CL1/TLR6	29
BP	GO:0035601	protein deacylation	50/7096	103/18670	0.01848	0.08956	0.06677	PINK1/SKI/ABHD13/BCL6/LYPLAL1/SIRT4/ABHD12/PER2/ABHD17C/MORF4L2/LYPLA2/TGFB1/SIN3A/MTA3/MSL3/ZBTB7B/VEGFA/SIRT7/HDAC11/MIER1/SMARCAD1/SIRT1/SFPQ/SIN3B/SUDS3/LRRK2/BRMS1L/HDAC10/HDAC2/AKAP8/HDAC7/MAPK8/NACC2/SIRT5/PRKD2/HDAC4/SPRED1/FRY/CAMK2D/ELK4/PRKAA1/IFNG/JDP2/TBL1X/HDAC5/BEX4/TADA3/MTA2/ATXN3L/BRMS1	50
BP	GO:0061387	regulation of extent of cell growth	53/7096	110/18670	0.0185	0.08957	0.06678	RTN4R/FN1/DPYSL2/WNT5A/SEMA4B/SPP1/RAB11A/ULK2/IFRD1/APOE/GSK3B/CXCL12/TWF2/SIN3A/PAK1/MEGF8/SRF/SEMA4A/VEGFA/CDK5/TNFRSF12A/ABL1/PAFAH1B1/GDI1/SEMA4C/SEMA4D/LRP1/DCC/CYFIP1/SEMA6B/NRP1/DISC1/SEMA3B/DNM2/L1CAM/LPAR3/IST1/NDEL1/OLFM1/WDR36/SEMA5A/FSTL4/SEMA5B/MAP3K13/RUFY3/PLXNA3/RTN4/CRABP2/FGF13/MACF1/TRPV2/TRIM46/BMPR2	53
BP	GO:0036498	IRE1-mediated unfolded protein response	33/7096	64/18670	0.01858	0.08983	0.06697	EXTL2/LMNA/TPP1/FKBP14/EDEM1/TLN1/WFS1/SSR1/HSPA5/TMEM33/PARP16/SHC1/WIPI1/VAPB/GOSR2/SERP1/PDIA6/KDELR3/BCL2L11/BAX/ACADVL/DNAJB9/CTDSP2/GFPT1/BFAR/HYOU1/PPP2R5B/YIF1A/ERN1/BAK1/PREB/ARFGAP1/HDGF	33
BP	GO:0044783	G1 DNA damage checkpoint	33/7096	64/18670	0.01858	0.08983	0.06697	CDKN1A/RGCC/GIGYF2/BTG2/PLK2/SFN/PML/CCND1/ATM/TNKS1BP1/MUC1/PLK3/PCNA/BAX/CRADD/CASP2/RFWD3/CDKN1B/CNOT4/PLAGL1/ARID3A/E2F4/CNOT7/GML/MDM2/RBL2/CNOT10/CARM1/TRIAP1/AURKA/SOX4/PRMT1/E2F8	33
BP	GO:0009612	response to mechanical stimulus	95/7096	210/18670	0.0186	0.08985	0.06698	MYD88/SLC8A1/JUNB/FOS/PKD2L1/FYN/PTGER4/BCL10/TXNIP/FOSB/IRF1/RETN/ATP1A1/JUND/PTGS2/LRP11/TNFRSF10A/CD40/PSPH/STAT1/ABHD12/FAS/P2RX7/NFKBIA/SLC9A1/CXCL10/NFKB1/PKD2/BTG2/CXCL12/RELA/TGFB1/PTK2B/TLR5/TLR4/HABP4/GCLC/CASP8/IL1B/CASP5/TIFAB/DMD/IGFBP2/RAF1/MKKS/RAC1/CHI3L1/TMC2/ETS1/CNN2/MAPK8/CRADD/HDAC4/CASP2/ASNS/CHRNA10/CASP1/ITGA2/CYBA/KCNK2/MMP14/TNFRSF10B/EGFR/FADD/CAV3/TLR8/MAP2K4/BAD/FOSL1/PKD1L2/BDKRB1/MAP3K1/TLR3/CACNB3/HPN/RHOA/TRPV4/DAG1/ENG/SMPD2/BAK1/TMC1/ATP1A2/ENDOG/MPO/GJA1/ACTA1/SHANK3/P2RY1/PTCH1/STRBP/MAPK9/GDF5/ERCC8/STRA6	95
BP	GO:0031589	cell-substrate adhesion	154/7096	354/18670	0.01864	0.08997	0.06707	MYADM/MYO1G/S100A10/FN1/RAC2/BST1/TSC1/GBP1/ITGA5/ITGB7/SORBS3/ITGB5/BCL6/PPARD/NEDD9/FLNA/CIB1/ACTN4/LAMB2/CD44/TRIP6/JAK2/AKIP1/LDB1/VCL/SLC9A1/GSK3B/PTPRO/THBS3/DUSP3/PEAK1/AXL/PARVB/CD36/PTK2B/LAMC3/ITGAL/ADAM15/SRF/ACTN1/CD63/CORO1A/NINJ1/ITGA4/ITGA7/LAMB3/VEGFA/CDK5/VAMP3/TNFRSF12A/ABL1/ITGA11/EPDR1/MMP12/TESK2/LRP1/CRK/PPM1F/SLK/RAC1/ADAMTS12/DOCK5/RELL2/SNED1/TIMM10B/PTK2/ARHGAP6/EMILIN3/BCR/LIMCH1/ZYX/EDA/SRGAP2/HPSE/CD96/BCL2L11/EMP2/NRP1/DISC1/BCL2/DNM2/WDPCP/L1CAM/SERPINE1/BCAS3/MICALL2/UNC13D/KANK1/MADCAM1/TRIOBP/LGALS1/ITGA2/SPOCK2/FER/VWF/ITGA3/MMP14/DMTN/CORO1C/CALR/PXN/ATXN3/CLASP2/C1QBP/RCC2/JAM3/FZD4/PREX1/ADAM9/WNT1/MKLN1/MERTK/EMID1/APOA1/ITGA8/EPHB1/SKAP1/SPOCK1/HRG/BCAM/GCNT2/CD34/MEGF9/FZD7/TACSTD2/MEN1/NID1/ARPC2/PRKCZ/SIGLEC1/LYVE1/MAP4K4/RHOA/TYRO3/LIMS1/DAG1/CX3CL1/ITGB1BP1/MSLN/FOXF1/CCR7/CD3E/EMILIN2/ROCK2/ATXN3L/TMEM8B/HOXA7/KIF14/MACF1/HSD17B12/ADAMTS9/PIK3CB/PTPRJ/FMN1	154
BP	GO:0035307	positive regulation of protein dephosphorylation	24/7096	44/18670	0.01879	0.0903	0.06732	LILRB2/PINK1/CAMTA1/PPP1R15A/JAK2/PTPRC/TGFB1/PRKCD/SLC39A10/SYMPK/PPP1R15B/PPP1R16B/CDH5/ANKLE2/CD300A/PPP1R7/NSMF/PIN1/SMPD1/PPP1R14D/HSP90AB1/CD33/CDCA2/MTOR	24
BP	GO:0090382	phagosome maturation	24/7096	44/18670	0.01879	0.0903	0.06732	SRPX/ATP6V0D2/SYT11/ATP6V1C1/P2RX7/ATP6V0C/RAB31/UNC13B/CORO1A/TCIRG1/ATP6V1A/RAB20/ATP6V1G3/RAB43/ATP6V1B2/RAB32/RAB38/ATP6V1D/ATP6V0E2/RAB7B/ATP6V1G2/MREG/ATP6V1B1/SLAMF8	24
BP	GO:1901028	regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	24/7096	44/18670	0.01879	0.0903	0.06732	SLC35F6/PMAIP1/YWHAH/TMEM14A/GSK3B/MPV17L/FZD9/SFN/CASP8/CHCHD10/SLC25A5/MAPK8/TMEM102/BCL2/BAX/GZMB/YWHAQ/MUL1/ACAA2/YWHAE/BAD/PPP1R13B/YWHAG/BAK1	24
BP	GO:1904407	positive regulation of nitric oxide metabolic process	24/7096	44/18670	0.01879	0.0903	0.06732	KLF4/KLF2/CLEC7A/PTGS2/JAK2/TNF/DDAH2/PKD2/TICAM1/CD36/PTK2B/INSR/HBB/PTX3/TLR4/IL1B/AIF1/CLU/DNM2/AGXT2/IFNG/HSP90AB1/MTOR/TLR6	24
BP	GO:2000404	regulation of T cell migration	24/7096	44/18670	0.01879	0.0903	0.06732	CCR2/IL27RA/OXSR1/WNT5A/TNFRSF14/ADAM8/CXCL10/CXCL12/DOCK8/CXCL13/ITGA4/AIF1/CCL5/CRK/CD200R1/CD99L2/TMEM102/CCR6/FADD/ADAM17/CCL20/C10orf99/RHOA/APP	24
BP	GO:0030308	negative regulation of cell growth	85/7096	186/18670	0.01879	0.0903	0.06732	RTN4R/CDKN2D/CDKN1A/FBP1/PPP2CA/OSGIN1/WNT5A/SEMA4B/SPP1/BCL6/PPARD/ADIPOR1/ULK2/RGS2/IFRD1/SH3BP4/PSRC1/TGFB1/PAK1/OSGIN2/BCL11A/ADAM15/HYAL2/NDUFS3/SEMA4A/RBBP7/CDK5/ENO1/NDRG3/SEMA4C/PML/SEMA4D/SIRT1/CDKN2AIP/CTDP1/ACVR1B/DCC/G6PD/FLCN/DDX3X/WFDC1/SEMA6B/ING1/BTG1/NRP1/SEMA3B/BCL2/EI24/CDKN1B/CDKN2C/YY1/FHL1/INHBA/ST20/SEMA5A/FSTL4/SERTAD2/MUL1/PPARA/CAV3/SLIT2/ADIPOR2/TCHP/SEMA5B/DCSTAMP/CYP27B1/DCUN1D3/PLXNA3/NAIF1/HRG/BDKRB1/JADE1/MSX1/CDA/RTN4/FGF13/DCBLD2/GJA1/SESN2/WT1/TRIM46/PTPRJ/PRDM11/BMPR2/SLIT3	85
BP	GO:0048194	Golgi vesicle budding	40/7096	80/18670	0.01894	0.09093	0.06779	SERPINA1/F5/MCFD2/KLHL12/CTSC/SEC22B/CD59/ANKRD28/SAR1B/TRAPPC6A/CSNK1D/PPP6R1/CNIH3/TRAPPC5/CTSZ/ARFGAP3/TMED10/BET1/VAPB/GOSR2/STX5/SAR1A/PPP6C/TRAPPC6B/TRAPPC9/GOLPH3L/NAPA/TBC1D20/COL7A1/LMAN1/PEF1/INSIG1/SEC23IP/TRAPPC2L/TRAPPC3/SCFD1/PREB/SEC24A/SEC31B/SEC16B	40
BP	GO:1902652	secondary alcohol metabolic process	72/7096	155/18670	0.01904	0.09136	0.06811	POR/CYP27A1/SOD1/NFYC/GPAM/NPC2/PPARD/APOC1/SCARB1/SQLE/SOAT1/CETP/RAN/APOE/HMGCR/LIMA1/HDLBP/CLN8/OSBPL1A/HMGCS1/SCD/LEP/ERLIN1/CNBP/CEBPA/CAT/ACLY/ABCA1/LDLR/LMF1/ERLIN2/FDPS/ACACB/APOBR/DGAT2/G6PD/FGF1/ARV1/APOL1/GNB3/TM7SF2/APOA5/MSMO1/IDI1/LCAT/RXRA/SCAP/ABCG1/APOL2/SC5D/CH25H/CLN6/SREBF2/ACADVL/CYB5R3/FDX1/NFE2L1/SERPINA12/INSIG1/ACAA2/PRKAA1/APOA1/CYP27B1/SMPD1/MBTPS2/APP/ELOVL6/MBTPS1/KPNB1/CYP46A1/NR1H4/SNX17	72
BP	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	17/7096	29/18670	0.01936	0.09229	0.0688	E2F6/ZPR1/KLF11/CCNE1/PCNA/ID2/TYMS/RRM2/NPAT/E2F4/DHFR/CCNA1/BACH1/RB1/POLA1/ESRRB/HINFP	17
BP	GO:0006929	substrate-dependent cell migration	17/7096	29/18670	0.01936	0.09229	0.0688	FN1/FMNL1/PTPRC/ADAM8/NCK1/TNFRSF12A/ITGA11/OPHN1/SDCBP/P2RY12/EPHA8/NRP1/NRP2/ITGA2/CD2AP/SLIT2/ITGB1BP1	17
BP	GO:0033014	tetrapyrrole biosynthetic process	17/7096	29/18670	0.01936	0.09229	0.0688	FECH/UROD/ALAD/ABCB6/CPOX/TMEM14C/SRRD/MMAB/MMACHC/COX15/IREB2/NFE2L1/RSAD1/ALAS1/SPTA1/SLC25A38/SLC25A39	17
BP	GO:0033032	regulation of myeloid cell apoptotic process	17/7096	29/18670	0.01936	0.09229	0.0688	NOD2/CLEC5A/ANXA1/IRF7/THRA/KITLG/MIF/SLC7A11/CCL5/SIRT1/CCR5/BCL2/PIK3CD/CXCR2/ADAM17/MEF2C/PIK3CB	17
BP	GO:0035666	TRIF-dependent toll-like receptor signaling pathway	17/7096	29/18670	0.01936	0.09229	0.0688	IRF7/BIRC2/LY96/TICAM1/UBE2D3/IKBKG/TLR4/TRAF3/UBE2D2/CASP8/CD300LF/BIRC3/UBC/FADD/TLR3/CHUK/TLR6	17
BP	GO:0042226	interleukin-6 biosynthetic process	17/7096	29/18670	0.01936	0.09229	0.0688	TLR1/CLEC7A/BCL10/STAT3/NLRP12/CEBPB/TNF/CD74/PTAFR/TRAF6/IL1B/AGER/TYROBP/APP/TIRAP/TLR6/GHRL	17
BP	GO:0045980	negative regulation of nucleotide metabolic process	17/7096	29/18670	0.01936	0.09229	0.0688	CBFA2T3/FBP1/STAT3/NUPR1/PPARGC1A/FLCN/SLC25A12/MYOG/PFKFB1/HDAC4/DDIT4/PPARA/DNAJC15/PID1/CDA/RHOA/SNCA	17
BP	GO:0072538	T-helper 17 type immune response	17/7096	29/18670	0.01936	0.09229	0.0688	NFKBIZ/IL27RA/STAT3/NLRP3/SMAD7/LY9/BATF/ZBTB7B/NFKBID/IL6/IL12RB1/RORA/IL12B/TBX21/PRKCQ/MALT1/IL23A	17
BP	GO:1900027	regulation of ruffle assembly	17/7096	29/18670	0.01936	0.09229	0.0688	EVL/RDX/PFN1/RHOG/HRAS/FAM98A/P2RY12/PLEKHM1/CYFIP1/SH3YL1/WDPCP/KANK1/NDEL1/CORO1C/RCC2/TACSTD2/EPS8L2	17
BP	GO:0051592	response to calcium ion	69/7096	148/18670	0.01948	0.09278	0.06917	CRHBP/JUNB/FOS/KCNMB1/DUSP1/ALOX5AP/MEF2A/TXNIP/FOSB/WNT5A/MCOLN1/SYT11/JUND/RASGRP2/LGMN/P2RX7/AKR1C3/PKD2/KCNIP2/PTK2B/CPNE8/RYR1/ALG2/HSPA5/GDI1/CCND1/TRPM2/HOMER1/SYT6/CLIC4/ADCY1/SPARC/SLC25A12/NEDD4/FUS/PEF1/HNRNPD/DMTN/CACYBP/CAMK2D/AHCYL1/EGFR/TPH2/SLC25A13/SYT13/AQP3/ADAM9/GIPR/CPNE1/PRKAA1/BAD/SYT9/RASAL1/CAPN3/CASQ2/CHP2/CPNE3/SLC25A24/SYT1/CPNE9/SUCNR1/SYT2/SYT4/SYT5/KCNMA1/CPNE2/KCNMB4/ENDOG/MEF2C	69
BP	GO:0043434	response to peptide hormone	187/7096	436/18670	0.0195	0.09281	0.06919	CRHBP/SH2B2/ATP6V0D2/SLC27A1/FYN/TLR2/PDK4/ANXA1/PRKAR2B/APPL2/SOCS3/NR4A2/LYN/POR/TSC1/CSK/RETN/SRSF5/SRD5A1/ATP6AP1/RAP1B/STAT6/STAT3/PTPN2/CCND3/JUND/PTGS2/HADH/ATP6V1C1/ADIPOR1/STAT1/JAK2/GSTP1/EGR1/PRKACB/C2CD5/ATP6V0C/SLC9A1/CISH/NFKB1/GSK3B/GAB1/BTG2/RAB31/CXCL12/PIK3R3/KAT2B/GKAP1/PKM/RELA/PDK2/TRIM16/SLC2A8/EIF6/CDK4/TGFB1/PAK1/ENHO/MYO5A/PCK2/LEP/SYAP1/PRKCD/INSR/BAIAP2/TCIRG1/EIF2B5/ZBTB7B/IGF1R/NCK1/CAT/ATP6V1A/TNFSF10/GCLC/STAT5A/IL1B/AGTRAP/SIK2/SHC1/PHIP/QDPR/CREB1/CRK/RAB8A/ATP6V1G3/SIRT1/BMP7/ARID1B/EIF4EBP2/FABP3/EGR2/ATP6V1B2/ADCY7/IRS2/CYFIP1/MYO1C/DENND4C/TIMP4/MBD5/ADCY1/SPARC/ATP6V1D/PTK2/GCNT1/GRB10/BTG1/KHK/PFKFB1/ADCY3/GNAI2/ATP6V0E2/SCAP/INPP5K/GPR21/CDKN1B/TIMP1/SRSF6/RHOQ/CPEB1/PRKACA/KANK1/NDEL1/PPAT/GRB2/CYBA/CYBB/FOXO4/FER/GOT2/CAMK2A/ATP6V1G2/HADHA/CACYBP/PXN/NFE2L2/SERPINA12/AHCYL1/RAB8B/SLC25A33/PPARA/KL/WNT1/PRKAA1/MDM2/PID1/SOCS1/REG3G/EIF2B1/SRSF4/CAD/ZNF106/OGT/NR4A3/EIF2B3/CCNA2/MEN1/YWHAG/SLA2/STXBP3/PRKCZ/MTOR/PRKCQ/HDAC5/TRPV4/DAG1/ATP6V1B1/PNPT1/SLC30A10/CHUK/SMARCC1/GCG/GHR/EIF2B2/ROCK2/APPL1/SOCS2/GJA1/INPPL1/KLF15/NUCKS1/NR1H4/STXBP4/SESN2/MGARP/CPEB2/FOXO3/GHRL	187
BP	GO:0042440	pigment metabolic process	36/7096	71/18670	0.01959	0.09317	0.06946	BLVRB/WNT5A/FECH/SLC7A11/HMOX1/UROD/ZEB2/GMPS/ALAD/RAPGEF2/MYO5A/PAICS/ASIP/CPOX/TMEM14C/SRRD/BDH2/PPARGC1A/BCL2/PRPS1/GPR143/PPAT/COX15/AMBP/IREB2/ADA/NFE2L1/SHMT1/DCT/ALAS1/CDH3/OCA2/SLC25A38/SLC25A39/APPL1/CTNS	36
BP	GO:0006906	vesicle fusion	46/7096	94/18670	0.01967	0.09348	0.06969	ANXA1/STX7/STX11/GNAI3/TAP2/TAP1/SEC22B/SAMD9L/C2CD5/VPS41/STXBP1/CORO1A/VAMP3/SAMD9/RAB20/ANKRD27/BET1/RAB8A/DOC2B/GOSR2/GOSR1/TAPBP/STX5/SPHK1/VPS18/STX16/NKD2/VTI1A/RAB7B/CALR/RAB8B/ANXA2P2/RAB3A/STX12/VTI1B/SYT9/STX8/SYT1/KIF5B/VPS16/VAMP1/SNAP29/SYT4/ANXA2/SNCA/VPS8	46
BP	GO:0031122	cytoplasmic microtubule organization	28/7096	53/18670	0.01975	0.09373	0.06988	EZR/RAB11A/CHP1/CIB1/IFT172/CCDC88B/PCM1/STMN3/PAFAH1B1/HOOK2/SLK/CCDC88A/PLK3/HOOK3/TUBGCP3/KATNA1/TUBG2/TUBGCP5/CAV3/CRIPT/DVL1/KATNAL1/SLAIN2/CCDC13/CEP120/TRPV4/KPNB1/FIGNL1	28
BP	GO:1902099	regulation of metaphase/anaphase transition of cell cycle	28/7096	53/18670	0.01975	0.09373	0.06988	DUSP1/MAD2L2/DYNC1LI1/SPDL1/CENPE/KLHL22/CDK5RAP2/NSMCE2/CDC23/ESPL1/ZNF207/LCMT1/ATM/ANAPC5/BUB3/NDC80/GEN1/ZW10/MOS/CDC26/RIOK2/DLGAP5/ANAPC4/CDC20/PCID2/RB1/ANAPC11/IK	28
BP	GO:0030203	glycosaminoglycan metabolic process	74/7096	160/18670	0.01979	0.09374	0.06988	FUCA1/HS3ST2/HEXB/VCAN/ABCC5/EXTL2/CHSY1/NDST2/HS2ST1/PIM1/NAGLU/CHP1/IDS/CD44/IL15/IMPAD1/SLC9A1/EXT2/EXT1/NFKB1/HEXA/CHST13/TGFB1/B3GNT2/ARSB/HGF/SGSH/CHST2/HYAL2/B4GALT6/CSGALNACT1/GNS/IL1B/CSPG4/ST3GAL2/XYLT1/CHST11/SLC35D1/B3GALT6/GLCE/CHST5/IDUA/PDGFB/CHST14/XYLT2/GUSB/HPSE/NDST1/CSGALNACT2/HS3ST1/CLN6/SPOCK2/B4GALT5/HYAL3/PGLYRP4/BCAN/AP2A1/HS3ST3B1/CEMIP/GPC2/B3GNT4/ST3GAL1/STAB2/CHST12/GCNT2/B3GAT3/HS3ST6/GPC4/LYVE1/SDC3/B4GALT1/SLC35D2/ITIH3/CHST7	74
BP	GO:0031532	actin cytoskeleton reorganization	49/7096	101/18670	0.0198	0.09374	0.06988	EZR/ANXA1/SIPA1L1/NOTCH2/ARAP1/HCK/RHOBTB1/NEDD9/FLNA/S1PR1/F11R/ARHGDIA/GAB1/HCLS1/TGFB1/PLEK2/PARVB/PAK1/PHACTR1/PTK2B/GMFG/BAIAP2/ARHGDIB/CDK5/HRAS/ABL1/DTNBP1/SHC1/ATP2C1/TRPM2/MYH9/NRP1/BCAS3/MICALL2/PLEK/FER/CD2AP/DMTN/EFS/ABL2/MKLN1/CSF1R/RHOA/TRPV4/PDLIM4/THSD7B/RHOBTB2/NRK/PHPT1	49
BP	GO:1903426	regulation of reactive oxygen species biosynthetic process	49/7096	101/18670	0.0198	0.09374	0.06988	KLF4/KLF2/FYN/CX3CR1/ATP2B4/ACP5/CLEC7A/ARG2/STAT3/PTGS2/JAK2/TNF/DDAH2/PKD2/TICAM1/CD36/PTK2B/INSR/HBB/PTX3/MPV17L/TLR4/IL1B/AIF1/CLU/RAC1/GLA/DNM2/HDAC4/CD47/CYBA/UCP1/AGXT2/SLC25A33/IFNG/CD34/HSP90AB1/DUOXA1/WDR35/MTOR/RHOA/SNCA/ABCD1/SLC30A10/ROCK2/CTNS/RAB27A/TLR6/FOXO3	49
BP	GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus	32/7096	62/18670	0.01993	0.09412	0.07017	IL27RA/MAD2L2/STAT6/BCL6/CD40/PTPRC/BATF/TGFB1/UNG/SWAP70/HMGB1/ATM/XRCC4/MLH1/PARP3/HMGB2/ERCC1/CLCF1/CCR6/LIG4/BCL11B/TFRC/TNFSF4/EXO1/DCLRE1C/EXOSC3/POLB/TBX21/APLF/EXOSC6/PAXIP1/ATAD5	32
BP	GO:0016444	somatic cell DNA recombination	32/7096	62/18670	0.01993	0.09412	0.07017	IL27RA/MAD2L2/STAT6/BCL6/CD40/PTPRC/BATF/TGFB1/UNG/SWAP70/HMGB1/ATM/XRCC4/MLH1/PARP3/HMGB2/ERCC1/CLCF1/CCR6/LIG4/BCL11B/TFRC/TNFSF4/EXO1/DCLRE1C/EXOSC3/POLB/TBX21/APLF/EXOSC6/PAXIP1/ATAD5	32
BP	GO:0046824	positive regulation of nucleocytoplasmic transport	32/7096	62/18670	0.01993	0.09412	0.07017	PTGS2/FLNA/KHDRBS1/RAN/GSK3B/HCLS1/TGFB1/LEP/PRKCD/HYAL2/SFN/EMD/ZPR1/IL1B/UBR5/DHX9/MAVS/RBM27/NEDD4/PRKACA/RIOK2/PSEN1/MDM2/MAPK1/TCF7L2/YWHAE/IFNG/CHP2/XPO4/SMO/TARDBP/CTDSPL2	32
BP	GO:0055074	calcium ion homeostasis	201/7096	471/18670	0.01993	0.09412	0.07017	SLC8A1/FPR2/HTR2B/VDR/FPR1/CCR2/FYN/FAM20A/CX3CR1/PTGER4/PTPN6/S1PR4/HEXB/ATP2B4/LYN/CD55/WNT5A/MCOLN1/S1PR3/PTGER2/TPCN1/DIAPH1/TMBIM6/GNB1/S1PR1/CD40/GNA15/SNX10/ACKR3/P2RY8/CXCL9/JAK2/CXCL11/PTPRC/P2RX7/BCAP31/KCTD17/CXCL10/PKD2/APOE/CXCL12/ATF4/TGFB1/ITPR1/FIS1/WFS1/CD36/LPAR2/PTK2B/MYO5A/SWAP70/CORO1A/P2RY6/MCU/CXCL13/TCIRG1/RYR1/FZD9/CDK5/ABL1/CMKLR1/STIM2/GSTO1/CLN3/CCL5/PLCG2/PML/CYSLTR1/ATP2C1/LRP1/HMGB1/DMD/VAPB/CCL7/TRPM4/NPTN/ATP7B/AFG3L2/TRPM2/PDZD8/LPAR6/CXCR1/LCK/CDH5/CCR5/TMTC2/SRI/RASA3/C3AR1/CCL13/TMEM64/TRIM24/P2RX1/NMUR2/DISC1/ANXA6/BCL2/CCL8/TGM2/BAX/ATP1B1/MS4A1/CHRNA10/CCR6/PRKACA/LPAR3/GPR18/CXCR6/CCR4/CYBA/MICU1/LPAR1/MCOLN2/ATP13A5/PROK2/F2R/GRIN2C/CALR/SLC35G1/CAMK2D/PLCB1/CCR3/CEMIP/CXCR2/ABL2/NMB/CAV3/ATP2A2/HSP90B1/ANXA2P2/LETM1/KL/SLC8A2/GIPR/TACR1/PSEN1/GNA13/GPR35/GALR1/P2RY4/HCRTR1/YWHAE/SYPL2/CYP27B1/CASQ1/PLA2G6/SLC24A4/CAPN3/CASQ2/HRC/BDKRB1/GPR12/PKHD1/CD4/TMEM38B/LACRT/PIK3CG/CACNB3/OPRL1/ANXA2/LIME1/P2RY10/TRPV4/C5AR2/APP/GPR6/SNCA/CX3CL1/IAPP/CXCR3/P2RX2/ATP6V1B1/SLC24A2/CIB2/CCL19/CCKBR/BAK1/CHERP/GCM2/ATP1A2/CCR7/SLC8A3/MCOLN3/FAM155A/GJA1/ACKR2/GPR20/ADCYAP1R1/CCRL2/CD24/KEL/P2RY1/NTSR1/MICU2/GHRL/KISS1/PIK3CB/S100A14/P2RX5/SYNPO/GTF2I	201
BP	GO:0042149	cellular response to glucose starvation	23/7096	42/18670	0.02003	0.09451	0.07046	UPP1/PMAIP1/SIK1/ATG14/ATF4/HIGD1A/HSPA5/HNRNPA1/SIK2/KPTN/MYBBP1A/BCL2/ASNS/NFE2L2/IMPACT/ITFG2/SESN1/PRKAA1/MTMR3/SH3GLB1/TBL2/PICK1/SESN2	23
BP	GO:0060070	canonical Wnt signaling pathway	146/7096	335/18670	0.02009	0.0947	0.0706	KLF4/NR4A2/MAD2L2/RBPJ/WNT5A/PSMB9/JRK/ZBED3/KLHL12/PSMB8/WLS/CSNK1G2/LGR4/EGR1/PSMA5/DVL2/PSMD11/GPRC5B/NFKB1/APOE/GSK3B/PSME1/PTPRO/LRP5/GNAQ/PSMB10/IGFBP4/TLE1/PSMA1/MCC/PSMA4/CSNK1D/ROR2/LATS1/RUVBL2/RUVBL1/FUZ/FZD9/BMP2/TLE4/PSMB1/GID8/EMD/PSMC4/FRAT2/UBR5/FRAT1/MITF/RNF146/SFRP4/PSMD13/IGFBP2/PSMB3/TRPM4/TMEM170B/CYLD/LRRK2/MESP1/BCL9L/TCF7L1/ASPM/SULF2/DDX3X/PSMB5/PSMD6/CSNK1A1/EDA/CSNK1E/DIXDC1/PSMC3/TMEM64/NPHP4/NRARP/PSME3/DISC1/ZNF703/PSMC6/RAB5A/TLE6/KANK1/TMEM88/CSNK1G3/ZBED2/GSKIP/NKD2/MKS1/SEMA5A/FZD5/FZD1/DKK2/PPP1CA/EGFR/CCNY/FZD4/DVL1/WNT1/PSEN1/TCF7L2/LGR5/CTHRC1/IFT20/PSMC1/PSMD8/PSMA2/ARNTL/LATS2/PIN1/ANKRD6/FZD7/WNT2B/JADE1/PFDN5/TBL1X/PSMC5/LGR6/PSMC2/PSMB2/PSMD4/VCP/PRDM15/CDH3/FZD2/RBX1/SOX4/WNT10A/SDHAF2/KREMEN1/XIAP/LRP4/PSMD1/WNT7A/SFRP5/AMER3/UBE2B/WNT10B/PSMB4/CSNK1G1/GREM1/DAAM2/PSMD9/PSMD3/SIAH2/FOXO3/FZD10/WNK2/SOX7	146
BP	GO:0000188	inactivation of MAPK activity	16/7096	27/18670	0.02027	0.0952	0.07098	DUSP1/DUSP6/PPP2CA/DUSP5/DUSP10/DUSP7/DUSP3/DUSP18/MBIP/DUSP2/DUSP14/RGS3/DUSP4/LAX1/SPRED1/GPS1	16
BP	GO:0006735	NADH regeneration	16/7096	27/18670	0.02027	0.0952	0.07098	HK3/PGK1/PFKM/PFKP/GAPDH/PGAM1/PKM/TPI1/ALDOC/ENO1/ALDOA/GPI/FOXK2/ENO2/ADPGK/PFKL	16
BP	GO:0061621	canonical glycolysis	16/7096	27/18670	0.02027	0.0952	0.07098	HK3/PGK1/PFKM/PFKP/GAPDH/PGAM1/PKM/TPI1/ALDOC/ENO1/ALDOA/GPI/FOXK2/ENO2/ADPGK/PFKL	16
BP	GO:0061718	glucose catabolic process to pyruvate	16/7096	27/18670	0.02027	0.0952	0.07098	HK3/PGK1/PFKM/PFKP/GAPDH/PGAM1/PKM/TPI1/ALDOC/ENO1/ALDOA/GPI/FOXK2/ENO2/ADPGK/PFKL	16
BP	GO:0032273	positive regulation of protein polymerization	63/7096	134/18670	0.02027	0.0952	0.07098	CDC42EP4/VASP/ARF6/PINK1/HCK/RHOBTB1/SPIRE1/IQGAP2/ACTR2/EVL/PSRC1/PFN1/CDC42EP2/PAK1/CLIP1/PTK2B/GMFG/CORO1A/BAIAP2/NCK1/FCHSD1/CDK5RAP2/ARPC1A/MAPRE1/TPPP3/RAC1/ARPIN/TTBK1/ARPC1B/CDC42EP3/CYFIP1/MYO1C/CORO1B/ARF1/ARPC5L/CDKN1B/GRB2/JMY/ACTR3B/FER/ACTR3/LMOD3/CAV3/SCIN/CCL26/ARPC4/SLAIN2/ARPC2/MTOR/NAV3/RHOA/PICK1/SNX9/MET/CCR7/WAS/RHOBTB2/CCL24/TPPP/BIN1/NCKAP1/FCHSD2/FMN1	63
BP	GO:0008088	axo-dendritic transport	35/7096	69/18670	0.02102	0.09759	0.07275	APBA1/SOD1/BLOC1S2/UCHL1/KIF3B/HIF1A/HSPB1/AP3M2/TRAK2/PURA/PAFAH1B1/DTNBP1/BLOC1S6/KIF4A/SFPQ/FLOT2/ARL8A/BLOC1S3/NDEL1/BLOC1S1/BLOC1S4/AP3B1/MAP1A/FMR1/KIF17/KIF1B/AP3M1/KIF5B/TRAK1/KIF1C/APP/KLC3/MGARP/ARL8B/TRIM46	35
BP	GO:0002730	regulation of dendritic cell cytokine production	8/7096	11/18670	0.02104	0.09759	0.07275	NOD2/DDX21/TICAM1/TLR4/DDX58/MAVS/DDX1/TLR3	8
BP	GO:0006054	N-acetylneuraminate metabolic process	8/7096	11/18670	0.02104	0.09759	0.07275	NANP/GNPDA1/NPL/NAGK/RENBP/CMAS/ST3GAL1/GNE	8
BP	GO:0019042	viral latency	8/7096	11/18670	0.02104	0.09759	0.07275	IRF7/XRCC5/HMGA1/XRCC4/BANF1/LIG4/XRCC6/NUCKS1	8
BP	GO:0033235	positive regulation of protein sumoylation	8/7096	11/18670	0.02104	0.09759	0.07275	HDAC4/TOLLIP/ARNT/PIAS3/MUL1/UBE2I/GNL3/RASD2	8
BP	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly	8/7096	11/18670	0.02104	0.09759	0.07275	PSMC4/CREB1/PSMC3/CAND1/PSMC6/PSMC5/PSMC2/WNT10B	8
BP	GO:0046886	positive regulation of hormone biosynthetic process	8/7096	11/18670	0.02104	0.09759	0.07275	POR/EGR1/TNF/HIF1A/IL1B/PPARGC1A/ARNT/IFNG	8
BP	GO:0070757	interleukin-35-mediated signaling pathway	8/7096	11/18670	0.02104	0.09759	0.07275	IL27RA/STAT3/STAT1/JAK2/IL6ST/EBI3/CANX/JAK1	8
BP	GO:0071372	cellular response to follicle-stimulating hormone stimulus	8/7096	11/18670	0.02104	0.09759	0.07275	GCLM/POR/HMGCS1/GCLC/PPARGC1A/EPHA8/INHBA/FSHR	8
BP	GO:1900102	negative regulation of endoplasmic reticulum unfolded protein response	8/7096	11/18670	0.02104	0.09759	0.07275	PPP1R15A/WFS1/HSPA5/NCK1/PPP1R15B/DNAJB9/BFAR/ATF6B	8
BP	GO:1902065	response to L-glutamate	8/7096	11/18670	0.02104	0.09759	0.07275	FYN/AIFM1/TMBIM6/BCL11A/BAIAP2/CREB1/PCNA/AMIGO1	8
BP	GO:1902946	protein localization to early endosome	8/7096	11/18670	0.02104	0.09759	0.07275	EZR/RDX/DTX3L/NRP1/MGAT3/LRRC7/MSN/ROCK2	8
BP	GO:2000318	positive regulation of T-helper 17 type immune response	8/7096	11/18670	0.02104	0.09759	0.07275	NFKBIZ/NLRP3/NFKBID/IL12RB1/IL12B/PRKCQ/MALT1/IL23A	8
BP	GO:2001204	regulation of osteoclast development	8/7096	11/18670	0.02104	0.09759	0.07275	SIGLEC15/NOTCH2/ATP6AP1/FBXW7/LILRB1/TYROBP/CLDN18/SLC9B2	8
BP	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	8/7096	11/18670	0.02104	0.09759	0.07275	SRPX/CTNNA1/HTRA2/WWOX/INHBA/PPP1CA/PPP2R1B/RET	8
BP	GO:0050900	leukocyte migration	212/7096	499/18670	0.02108	0.09759	0.07275	TREM1/S100A9/MYO1G/S100A8/ITGAM/FPR2/S100A12/CCR2/FN1/FYN/CX3CR1/PTGER4/RAC2/PTPN6/IL27RA/SELL/DUSP1/ANXA1/BST1/LYN/DOK2/OXSR1/WNT5A/GYPC/OLR1/AZU1/ITGA5/CD58/IL17RA/FLT1/PROS1/ITGB7/HCK/VEGFB/TNFRSF14/TNFRSF10A/CAMK1D/S1PR1/KITLG/MIF/CD2/PPBP/LGMN/CD44/CXCL9/F11R/NLRP12/PLA2G7/CXCL11/TNFRSF10D/ADAM8/TNF/SLC7A11/CD74/HMOX1/CXCL10/FUT7/CXCL12/PTPRO/MPP1/DOCK8/IRAK4/TGFB1/SLC7A7/NUP85/PTAFR/FFAR2/PTK2B/LEP/ITGAL/SWAP70/ROR2/SLC7A6/CORO1A/CXCL13/AIMP1/ITGA4/SLC7A5/CD99/ABR/VEGFA/PDE4B/CMKLR1/IL1B/AIF1/VPREB3/AGER/CCL5/SHC1/P2RY12/HMGB1/THBD/TNFRSF11A/CRK/CCL7/TNFRSF18/IL1RN/TRPM4/IL1R1/TRPM2/CEACAM3/RAC1/ATP1B2/CXCR1/IL6/LCK/PDGFB/CD200R1/IL16/CCR5/CKLF/GCNT1/BCR/MYH9/ATP1B3/SELPLG/SLC12A2/RPS19/C3AR1/MOSPD2/CCL13/BMP5/GPSM3/CD99L2/ZNF580/TMEM102/SLC7A8/CCL8/L1CAM/SERPINE1/PIK3CD/CD47/ATP1B1/CCR6/MADCAM1/SLC16A1/ITGA2/GPR18/CH25H/CREB3/GRB2/CD300A/GRB7/LGALS9/MMP1/FER/GCSAM/RABGEF1/CNR2/ITGA3/MMP14/MCOLN2/ADA/CALR/GPR15/TNFRSF10B/PLCB1/MST1/C1QBP/VAV1/CXCR2/FADD/ADAM17/CCL20/JAM3/PREX1/SLIT2/CCL26/MERTK/MSN/SIRPG/TREM2/CD84/TNFSF18/RET/CSF3R/BDKRB1/CD34/C10orf99/PIK3CG/LBP/DBH/GLG1/TBX21/PRTN3/SDC3/RHOA/TRPV4/C5AR2/APP/GPR183/DAPK2/CX3CL1/B4GALT1/CXCR3/CCL19/TIRAP/CD244/CEACAM8/CCL4/CCR7/GREM1/CCL24/HOXA7/SLAMF8/IL23A/IL17RC/CXCL6/PDGFD/PIK3CB/S100A14/IL37	212
BP	GO:0045444	fat cell differentiation	100/7096	223/18670	0.02109	0.09759	0.07275	KLF4/SH2B2/TRIM32/METRNL/PEX11A/NR4A2/ZFP36/FABP4/ARL4A/WNT5A/RETN/FNDC5/PTGS2/STEAP4/PPARD/DUSP10/PLAC8/PSMB8/RGS2/PER2/CEBPB/ATF5/CTBP2/TNF/ZNF516/ALDH6A1/GRK5/ZADH2/LRP5/ANKRD26/AAMDC/ZBTB7A/TGFB1/WDFY2/AACS/FFAR2/LEP/SYAP1/CBY1/NAPEPLD/ZBTB7B/LAMB3/CEBPA/ADRB1/BMP2/CMKLR1/MEX3C/CREB1/BBS2/BBS12/SIRT1/SAV1/TRPM4/MKKS/CREBL2/CCND1/EGR2/IL6/PPARGC1A/GNB3/BBS4/TMEM64/FTO/ID2/LRG1/TRIB2/ASXL2/ADRB2/KLF5/FFAR4/RNASEL/BBS7/HES1/UCP1/INSIG1/PLCB1/NUDT7/DLK2/BBS9/WNT1/TCF7L2/FAM120B/SOCS1/ZFP36L2/ERAP1/RORA/ARNTL/NR4A3/TGFB1I1/JDP2/CARM1/GPX1/MTOR/TRPV4/CLIP3/VSTM2A/ZBTB16/WNT10B/NOC3L/C1QTNF3	100
BP	GO:0009648	photoperiodism	15/7096	25/18670	0.02113	0.09759	0.07275	BHLHE40/SIK1/PER2/RBM4/RBM4B/PML/FBXL3/CRTC1/ID2/PPP1CC/PPP1CA/CLOCK/PPP1CB/PER3/NR2F6	15
BP	GO:0030813	positive regulation of nucleotide catabolic process	15/7096	25/18670	0.02113	0.09759	0.07275	IGF1/PFKFB3/P2RX7/HIF1A/INSR/PFKFB4/PFKFB1/PFKFB2/ARNT/PRKAA1/PSEN1/IFNG/ESRRB/ZBTB20/APP	15
BP	GO:0032616	interleukin-13 production	15/7096	25/18670	0.02113	0.09759	0.07275	ARG2/IL17RA/LILRA5/NLRP3/TNFRSF21/IL1RAP/HLA-E/SCGB1A1/LGALS9/IL18/TNFSF4/IL25/TSLP/PRKCZ/IL17RB	15
BP	GO:0033522	histone H2A ubiquitination	15/7096	25/18670	0.02113	0.09759	0.07275	RYBP/TRIM37/PCGF2/DDB1/PCGF1/PCGF3/UBR5/UBE2A/BCOR/DTX3L/KDM2B/RING1/DDB2/CUL4B/UBE2B	15
BP	GO:0051156	glucose 6-phosphate metabolic process	15/7096	25/18670	0.02113	0.09759	0.07275	TALDO1/HK3/PGAM1/RPE/TKT/RPIA/GPI/G6PD/PGM2/DERA/NFE2L1/PGD/G6PC/PGLS/RBKS	15
BP	GO:0051197	positive regulation of coenzyme metabolic process	15/7096	25/18670	0.02113	0.09759	0.07275	IGF1/PFKFB3/P2RX7/HIF1A/INSR/PFKFB4/PFKFB1/PFKFB2/ARNT/PRKAA1/PSEN1/IFNG/ESRRB/ZBTB20/APP	15
BP	GO:0030071	regulation of mitotic metaphase/anaphase transition	27/7096	51/18670	0.02115	0.09759	0.07275	DUSP1/MAD2L2/DYNC1LI1/SPDL1/CENPE/KLHL22/CDK5RAP2/NSMCE2/CDC23/ESPL1/ZNF207/LCMT1/ATM/ANAPC5/BUB3/NDC80/GEN1/ZW10/CDC26/RIOK2/DLGAP5/ANAPC4/CDC20/PCID2/RB1/ANAPC11/IK	27
BP	GO:0032007	negative regulation of TOR signaling	27/7096	51/18670	0.02115	0.09759	0.07275	TSC1/SIK1/SH3BP4/HIF1A/TNFAIP8L1/SIK2/NPRL3/SIRT1/KPTN/FLCN/ATM/TMEM127/MAPKAPK5/FNIP1/EPM2A/AKT1S1/TBC1D7/DDIT4/ITFG2/SESN1/DEPTOR/PRKAA1/UBR1/NPRL2/ARNTL/DEPDC5/SESN2	27
BP	GO:0007041	lysosomal transport	51/7096	106/18670	0.0212	0.09768	0.07282	GRN/PINK1/C9orf72/NCOA4/FAM160A2/ATG14/LAMP2/PSAP/LAMP1/M6PR/VPS41/ARSB/NAGPA/GNPTAB/DENND3/TRAK2/IGF2R/VPS33A/LRP1/CLU/HOOK2/TMEM106B/LRRK2/SNX27/ARF1/DTX3L/HOOK3/VPS18/VPS51/NEDD4/TSG101/ADRB2/VIPAS39/HGS/KIF13A/VPS52/VPS4B/RAB7B/GPRASP1/AP3B1/AP1G1/AP3M1/STX8/TRAK1/EHD3/CLEC16A/VPS16/VCP/SNX16/CCDC91/BIN1	51
BP	GO:0030838	positive regulation of actin filament polymerization	48/7096	99/18670	0.0212	0.09768	0.07282	CDC42EP4/VASP/ARF6/HCK/RHOBTB1/SPIRE1/IQGAP2/ACTR2/EVL/PFN1/CDC42EP2/PTK2B/GMFG/CORO1A/BAIAP2/NCK1/FCHSD1/ARPC1A/ARPIN/ARPC1B/CDC42EP3/CYFIP1/MYO1C/CORO1B/ARF1/ARPC5L/GRB2/JMY/ACTR3B/FER/ACTR3/LMOD3/SCIN/CCL26/ARPC4/ARPC2/MTOR/RHOA/PICK1/SNX9/CCR7/WAS/RHOBTB2/CCL24/BIN1/NCKAP1/FCHSD2/FMN1	48
BP	GO:0045124	regulation of bone resorption	22/7096	40/18670	0.02136	0.09824	0.07324	SIGLEC15/PDK4/CSK/ATP6AP1/SPP1/TNFAIP3/S1PR1/P2RX7/ADAM8/LTBP3/TNFRSF11A/PLEKHM1/IL6/TMEM64/EGFR/TFRC/DCSTAMP/CLDN18/CSF1R/IAPP/TMEM119/PRKCA	22
BP	GO:0071526	semaphorin-plexin signaling pathway	22/7096	40/18670	0.02136	0.09824	0.07324	SEMA4B/FLNA/ARHGDIA/PLXNB2/PLXNC1/NCAM1/SEMA4A/SEMA4C/SEMA4D/SH3BP1/RAC1/SEMA6B/PLXNA1/NRP1/SEMA3B/PLXND1/NRP2/SEMA5A/SEMA5B/PLXNA3/PLXNA2/MET	22
BP	GO:0019674	NAD metabolic process	38/7096	76/18670	0.02179	0.1001	0.07464	HK3/NAMPT/QPRT/BST1/LDHA/PARP9/PGK1/MDH1/PFKM/PTGS2/PFKP/GAPDH/NMNAT3/PGAM1/PKM/TPI1/ALDOC/NMNAT1/ENO1/IDO1/ALDOA/PARP16/NADK2/GPI/LDHB/KYNU/HAAO/SLC25A12/MDH1B/NMRK2/FOXK2/NMNAT2/IDO2/SLC5A8/ENO2/VCP/ADPGK/PFKL	38
BP	GO:0045454	cell redox homeostasis	38/7096	76/18670	0.02179	0.1001	0.07464	SCO2/RAC2/SLC11A1/SH3BGRL3/TXNDC16/GSR/QSOX2/PDIA3/TXNRD1/PRDX1/NCF4/NCF2/NCF1/QSOX1/TXNDC11/GCLC/ERP44/KRIT1/PDIA6/GLRX3/HVCN1/TXNDC12/TMX4/TXNDC8/PRDX6/DNAJC16/DNAJC10/CYBA/CYBB/NHLRC2/NFE2L2/TXN/NXNL1/TMX3/PDILT/GPX1/MPO/NNT	38
BP	GO:0045931	positive regulation of mitotic cell cycle	75/7096	163/18670	0.02183	0.1002	0.0747	IGF1/ANXA1/CCND3/NUP62/RAB11A/MEPCE/DYNC1LI1/LGMN/RGCC/LSM11/CCND2/TMOD3/DUSP3/LRP5/CDK4/TGFB1/RDX/SMC5/SIN3A/MTA3/INSR/DBF4B/UBXN2B/ABL1/PAFAH1B1/RAD51B/IL1B/AIF1/NSMCE2/NSFL1C/PHIP/CCND1/PDGFB/TAL1/ESPL1/DDX3X/ANAPC5/SPHK1/KMT2E/UBE2E2/CCNE1/NDC80/ANKRD17/ASNS/KIF20B/IL1A/CDC25A/GEN1/NUSAP1/VPS4B/UBE2C/HES1/DTL/DYNLT3/PLCB1/EGFR/PKN2/ADAM17/RCC2/MDM2/DLGAP5/EIF4G1/ANAPC4/MTBP/EIF4E/CUL4B/PCID2/RB1/TERT/AURKA/ANAPC11/APP/USP22/WNT10B/PRKCA	75
BP	GO:0002347	response to tumor cell	14/7096	23/18670	0.02192	0.1002	0.07472	TXNIP/HNMT/CD226/ADAM15/FBXO38/HMGB1/PVR/CD274/CRTAM/PRF1/HAVCR2/HRG/IL12B/MICA	14
BP	GO:0009147	pyrimidine nucleoside triphosphate metabolic process	14/7096	23/18670	0.02192	0.1002	0.07472	AK3/CTPS2/CMPK2/NME3/NME4/NME1/TYMS/UCK1/TBPL1/CTPS1/CAD/DCTPP1/UCKL1/DUT	14
BP	GO:0051043	regulation of membrane protein ectodomain proteolysis	14/7096	23/18670	0.02192	0.1002	0.07472	LRIG2/TIMP2/ADAM8/TNF/APOE/IL1B/FURIN/SNX33/TIMP4/TIMP1/ADAM9/IFNG/SNX9/PACSIN3	14
BP	GO:0060055	angiogenesis involved in wound healing	14/7096	23/18670	0.02192	0.1002	0.07472	TNFAIP3/SRF/ETS1/MIR34A/HPSE/SERPINE1/ADIPOR2/CD34/GPX1/DAG1/CX3CL1/B4GALT1/PIK3CB/MCAM	14
BP	GO:0071157	negative regulation of cell cycle arrest	14/7096	23/18670	0.02192	0.1002	0.07472	MIF/ZNF268/CDK4/TFAP4/FZD9/SETMAR/HMGN5/CCND1/CDK9/CCNK/EVI2B/CALR/MDM2/HSP90AB1	14
BP	GO:0016358	dendrite development	104/7096	233/18670	0.02193	0.1002	0.07472	FYN/SIPA1L1/ARF6/MEF2A/MAP1S/DNM3/CELSR2/LST1/CAMK1D/YWHAH/ALK/EZH2/DOCK10/EPHB2/BTBD3/APOE/GSK3B/ACTR2/LRP8/UBE3A/RAPGEF2/PHACTR1/ARF4/SS18L2/BCL11A/BAIAP2/ITSN1/ACSL4/CDK5/PLK2/TRAK2/PAFAH1B1/SRGAP2C/PAK2/GRIP1/DTNBP1/STRN/SEMA4D/MARK1/ANKRD27/CRK/BMP7/TMEM106B/ARID1B/CAPRIN1/KALRN/LRRK2/DCC/CYFIP1/ARC/KLF7/CRTC1/BBS4/ARF1/SRGAP2/PDLIM5/HDAC2/BMP5/NRP1/DISC1/NEDD4/CFL1/SYNGAP1/DAB1/SHANK1/CPEB3/LPAR1/CAMK2A/FSTL4/BHLHB9/DNM1L/NSMF/SS18L1/PREX1/DVL1/MAP1A/PSEN1/FMR1/CHRNB2/EPHB1/CDC20/TRAK1/IL1RAPL1/KNDC1/CARM1/NR2E1/RELN/MTOR/RHOA/APP/C21orf91/PARP6/TULP1/ASAP1/LRP4/WNT7A/CD3E/PICALM/LZTS1/SHANK3/GHRL/ZMYND8/MEF2C/CAMK2B	104
BP	GO:0018105	peptidyl-serine phosphorylation	131/7096	299/18670	0.02209	0.1009	0.07524	ATP2B4/MAPK12/PINK1/MAD2L2/WNT5A/SH2D3C/PTGS2/SMAD7/RPS6KA3/MIF/CSNK1G2/CD44/DYRK4/TNF/PRKACB/STK38L/VRK2/ERCC6/GSK3B/STK32C/MAPKAPK3/DYRK2/HCLS1/CSNK2A2/TGFB1/HGF/ARRB1/PAK1/MAPK7/CSNK1D/PRKCD/MAPK13/LATS1/DYRK1B/NSD1/NCK1/VEGFA/CDK5/PLK2/PAK2/NLK/MAP3K12/PAQR3/ARAF/MARK1/DMD/RAF1/PPM1F/CREBL2/TTBK1/IL6/PDGFB/LRRK2/SMYD3/ATM/TNKS1BP1/CSNK1A1/BCAR3/CSNK1E/MAPKAPK5/FNIP1/MARK3/DCLK2/MAPK8/PLCL1/BCL2/PRKD2/MAPKAPK2/BAX/INPP5K/MARK2/PRKACA/TLK1/MAP4K1/CSNK1G3/IFNK/OSM/MAP2K2/INPP5F/DDIT4/HIPK1/CAMK2A/DMTN/PWP1/DYRK3/CAMK2D/ULK1/EGFR/TXN/PKN2/ATR/SPRY2/PRKAA1/MAPK1/VRK1/EIF4G1/CLSPN/MKNK2/MAP3K13/LMTK2/PLCL2/HRC/IFNG/HIPK3/LATS2/RET/MASTL/OPRD1/MAPKAP1/HSP90AB1/STK32B/TRIM6/PRKCZ/MTOR/PRKCQ/CLK1/AURKA/APP/ERN1/SNCA/TTBK2/TOP1/PDCD10/BAK1/CHUK/GCG/ROCK2/CSNK1G1/PRKCA/NTRK2/MAPK9	131
BP	GO:0046470	phosphatidylcholine metabolic process	41/7096	83/18670	0.0223	0.101	0.07532	LPCAT2/SLC27A1/CDS1/PLA2G12A/ENPP2/CHPT1/CAPN2/ABHD4/APOC1/SCARB1/MBOAT1/PLBD1/CETP/PNPLA6/CSNK2A2/STARD10/PLA2G15/LDLR/PLB1/CSNK2B/STARD7/FABP3/ABHD3/RAB38/APOA5/PNPLA8/MFSD2A/PLA2G3/MBOAT2/LCAT/TMEM86B/CHKA/FABP5/DBI/APOA1/PLA2G6/SLC44A2/CHAT/LPCAT1/CHKB/LPCAT3	41
BP	GO:1990266	neutrophil migration	56/7096	118/18670	0.02232	0.101	0.07532	S100A9/S100A8/S100A12/RAC2/BST1/CAMK1D/PPBP/CXCL9/CXCL11/ADAM8/CD74/CXCL10/MPP1/IRAK4/CXCL13/CD99/PDE4B/IL1B/CCL5/CCL7/IL1RN/IL1R1/RAC1/CXCR1/CKLF/C3AR1/MOSPD2/CCL13/CD99L2/CCL8/PIK3CD/MCOLN2/C1QBP/VAV1/CXCR2/CCL20/JAM3/PREX1/SLIT2/CCL26/CSF3R/PIK3CG/LBP/PRTN3/C5AR2/DAPK2/CX3CL1/CCL19/TIRAP/CCL4/CCR7/CCL24/SLAMF8/IL23A/CXCL6/IL37	56
BP	GO:0001765	membrane raft assembly	9/7096	13/18670	0.02252	0.101	0.07532	S100A10/PACSIN2/FLOT1/FLOT2/EMP2/CAV3/ANXA2P2/ANXA2/RFTN1	9
BP	GO:0002679	respiratory burst involved in defense response	9/7096	13/18670	0.02252	0.101	0.07532	GRN/HCK/DUSP10/RPS19/PIK3CD/PIK3CG/LBP/MPO/SLAMF8	9
BP	GO:0002829	negative regulation of type 2 immune response	9/7096	13/18670	0.02252	0.101	0.07532	CCR2/IL27RA/ANXA1/ARG2/STAT6/BCL6/SOCS5/HLX/TBX21	9
BP	GO:0006596	polyamine biosynthetic process	9/7096	13/18670	0.02252	0.101	0.07532	SMS/OAZ2/SAT1/OAZ3/ODC1/AZIN1/SRM/AZIN2/AGMAT	9
BP	GO:0009223	pyrimidine deoxyribonucleotide catabolic process	9/7096	13/18670	0.02252	0.101	0.07532	NEIL2/UNG/NT5C/TDG/DCTPP1/NT5M/DUT/MBD4/SMUG1	9
BP	GO:0021554	optic nerve development	9/7096	13/18670	0.02252	0.101	0.07532	EPHB2/TCIRG1/LPAR1/KCNA2/CHRNB2/TMEM126A/RPL24/EPHB1/NAV2	9
BP	GO:0045086	positive regulation of interleukin-2 biosynthetic process	9/7096	13/18670	0.02252	0.101	0.07532	CLEC7A/PTPRC/IL1B/GLMN/IL1A/CD4/CD80/PRKCQ/CD3E	9
BP	GO:0047484	regulation of response to osmotic stress	9/7096	13/18670	0.02252	0.101	0.07532	PTGS2/ARHGEF2/EFHD1/MLC1/MICU1/YBX3/LETM1/BAD/TRPV4	9
BP	GO:0048711	positive regulation of astrocyte differentiation	9/7096	13/18670	0.02252	0.101	0.07532	MIR142/BMP2/IL6ST/TTBK1/ID2/CLCF1/HES1/PRPF19/BIN1	9
BP	GO:0051315	attachment of mitotic spindle microtubules to kinetochore	9/7096	13/18670	0.02252	0.101	0.07532	SEH1L/CENPE/MIS12/CENPC/CHAMP1/NDC80/NUF2/KIF2C/BOD1	9
BP	GO:1902902	negative regulation of autophagosome assembly	9/7096	13/18670	0.02252	0.101	0.07532	PINK1/FEZ2/SEC22B/NUPR1/CHMP4B/LRRK2/PHF23/SMCR8/SCFD1	9
BP	GO:1905330	regulation of morphogenesis of an epithelium	82/7096	180/18670	0.02254	0.101	0.07532	WNT5A/CELSR2/PSMB9/PSMB8/STAT1/LGR4/MAGED1/PSMA5/DVL2/TNF/PSMD11/CXCL10/PSME1/TGFB1/DAAM1/PFN1/HGF/PSMB10/PSMA1/PSMA4/ROR2/VEGFA/ABL1/PAX8/PSMB1/SAPCD2/PSMC4/PSMD13/PSMB3/BMP7/RAC1/ETV5/ADAMTS12/FGF1/PSMB5/PSMD6/PSMC3/RXRA/AP2A2/PSME3/BMP4/PSMC6/ROR1/AP2S1/PDGFA/MKS1/FZD5/AP2A1/FKBPL/FZD1/CLASP2/CAV3/FZD4/DVL1/WNT1/CTHRC1/PSMC1/HNF1B/PSMD8/PSMA2/BTBD7/ANKRD6/FZD7/TACSTD2/WNT2B/PSMC5/PSMC2/AP2M1/GPC4/PSMB2/PSMD4/MTOR/FOXP1/RHOA/FZD2/GRHL3/PSMD1/WNT7A/PSMB4/SMO/PSMD9/PSMD3	82
BP	GO:0032387	negative regulation of intracellular transport	34/7096	67/18670	0.02256	0.101	0.07532	RAP1B/BARD1/CHP1/SIRT4/HMOX1/RAB23/CD36/CDK5/SP100/GDI1/UBE2J1/RAP1A/MDFIC/UBE2G2/LRRK2/INPP5K/CD300A/LMAN1/LGALS9/RABGEF1/DMTN/DERL2/INSIG1/TXN/YOD1/FMR1/IL13RA2/CD84/PKIA/SYT4/ITGB1BP1/FOXF1/ERLEC1/OS9	34
BP	GO:0051298	centrosome duplication	34/7096	67/18670	0.02256	0.101	0.07532	NUP62/PKD2/KAT2B/CHMP4B/TRIM37/CEP131/SASS6/PLK2/NPM1/CDK5RAP2/KIAA0753/CEP76/SPICE1/CHMP2A/CKAP5/CEP152/GEN1/CHMP1A/VPS4B/CEP63/BRCA1/CETN1/CETN2/CHORDC1/KAT2A/PKHD1/CEP120/BRSK1/SAC3D1/CHMP1B/ROCK2/C2CD3/ALMS1/CCNF	34
BP	GO:1990138	neuron projection extension	77/7096	168/18670	0.02256	0.101	0.07532	RTN4R/FN1/DPYSL2/WNT5A/C9orf72/SEMA4B/RAB11A/ULK2/LAMB2/ALCAM/VCL/IFRD1/APOE/GSK3B/PLAA/CXCL12/TWF2/PPP3CB/SIN3A/PAK1/MEGF8/BCL11A/SRF/SEMA4A/ITGA4/VEGFA/USP9X/CDK5/TNFRSF12A/CYFIP2/ABL1/PAFAH1B1/GDI1/SEMA4C/SEMA4D/LRP1/CYFIP1/SEMA6B/PLXNA1/NRP1/DISC1/SEMA3B/DNM2/L1CAM/NRP2/NDEL1/OLFM1/WDR36/SEMA5A/IMPACT/ULK1/MUL1/ITSN2/SLIT2/DVL1/CPNE1/SEMA5B/POU4F3/RASAL1/MAP3K13/RUFY3/PLXNA3/SYT1/CPNE9/HSP90AB1/SYT2/EIF2AK4/SYT4/PRKCZ/AURKA/RTN4/RIMS2/MACF1/TRPV2/TRIM46/BMPR2/SLIT3	77
BP	GO:0001779	natural killer cell differentiation	13/7096	21/18670	0.0226	0.101	0.07532	PTPRC/IL15/AXL/ZBTB1/FLT3LG/RASGRP1/TOX/PIK3CD/ID2/PGLYRP4/MERTK/HNF1A/TYRO3	13
BP	GO:0009081	branched-chain amino acid metabolic process	13/7096	21/18670	0.0226	0.101	0.07532	HIBADH/HMGCL/BCKDK/ALDH6A1/AUH/DBT/ACADSB/MCCC1/HSD17B10/BCKDHB/BCAT2/BCKDHA/HMGCLL1	13
BP	GO:0009083	branched-chain amino acid catabolic process	13/7096	21/18670	0.0226	0.101	0.07532	HIBADH/HMGCL/BCKDK/ALDH6A1/AUH/DBT/ACADSB/MCCC1/HSD17B10/BCKDHB/BCAT2/BCKDHA/HMGCLL1	13
BP	GO:0010310	regulation of hydrogen peroxide metabolic process	13/7096	21/18670	0.0226	0.101	0.07532	FYN/RAC2/PINK1/STAT3/MPV17L/RAC1/NOXA1/MMP3/HP/DUOXA1/SNCA/CTNS/NNT	13
BP	GO:0030728	ovulation	13/7096	21/18670	0.0226	0.101	0.07532	PTGS2/RGS2/IL4R/TNFAIP6/HPGD/LEP/SIRT1/IMMP2L/INHBA/KMT2B/NRIP1/MMP19/FOXO3	13
BP	GO:0035743	CD4-positive, alpha-beta T cell cytokine production	13/7096	21/18670	0.0226	0.101	0.07532	CD55/NLRP3/DENND1B/IL18R1/RSAD2/IL1B/IL1R1/IL6/IL18/IL12B/PRKCZ/TBX21/IL18RAP	13
BP	GO:0036507	protein demannosylation	13/7096	21/18670	0.0226	0.101	0.07532	RNF103/MAN1C1/RNF139/TRIM13/EDEM1/EDEM2/MAN1B1/DERL2/MAN1A2/RNF185/RNF5/EDEM3/OS9	13
BP	GO:0036508	protein alpha-1,2-demannosylation	13/7096	21/18670	0.0226	0.101	0.07532	RNF103/MAN1C1/RNF139/TRIM13/EDEM1/EDEM2/MAN1B1/DERL2/MAN1A2/RNF185/RNF5/EDEM3/OS9	13
BP	GO:0046716	muscle cell cellular homeostasis	13/7096	21/18670	0.0226	0.101	0.07532	TRIM32/SOD1/PFKM/LAMP2/TGFB1/HIF1A/CFL2/SRF/ALDOA/DMD/CAV3/GAA/CAPN3	13
BP	GO:0051383	kinetochore organization	13/7096	21/18670	0.0226	0.101	0.07532	SENP6/CENPW/CENPE/CENPT/CENPN/MIS12/CENPC/SMC2/NDC80/NUF2/CENPK/CENPA/RNF4	13
BP	GO:0071459	protein localization to chromosome, centromeric region	13/7096	21/18670	0.0226	0.101	0.07532	SPDL1/MIS12/CHAMP1/BUB3/NDC80/CTCF/ZW10/RCC2/MTBP/CENPA/RB1/IK/BOD1	13
BP	GO:1900273	positive regulation of long-term synaptic potentiation	13/7096	21/18670	0.0226	0.101	0.07532	NRGN/LGMN/SQSTM1/EPHB2/STAU1/CREB1/NPTN/CRTC1/ADCY1/EIF2AK4/RELN/APP/SHANK3	13
BP	GO:1902307	positive regulation of sodium ion transmembrane transport	13/7096	21/18670	0.0226	0.101	0.07532	CHP1/ACTN4/SLC9A1/TESC/DMD/ATP1B2/ATP1B3/ARF1/FXYD1/DNM2/ATP1B1/KIF5B/WNK2	13
BP	GO:1902473	regulation of protein localization to synapse	13/7096	21/18670	0.0226	0.101	0.07532	WNT5A/GRIPAP1/HRAS/RAP1A/GRASP/IQSEC2/DVL1/PRKCZ/GPC4/DAG1/WNT7A/NLGN2/CLSTN3	13
BP	GO:0002534	cytokine production involved in inflammatory response	26/7096	49/18670	0.02266	0.1011	0.07535	MYD88/NOD2/IL1R2/CLEC7A/APPL2/IL17RA/GBP5/TICAM1/CHID1/SEH1L/LEP/TLR4/IDO1/C5orf30/ADCY7/CD96/GPSM3/MEFV/IL17B/BAP1/PDCD4/ABCD1/APPL1/NLRC3/TLR6/IL17RC	26
BP	GO:0008347	glial cell migration	26/7096	49/18670	0.02266	0.1011	0.07535	CCR2/CX3CR1/HEXB/SUN2/AZU1/MBOAT7/CERS2/CDK5/PAFAH1B1/SRGAP2C/CSPG4/P2RY12/LRP1/IDH2/SYNE2/SRGAP2/DISC1/DAB1/MMP14/CDK5R2/TREM2/NR2E1/RELN/GPR183/RTN4/P2RY1	26
BP	GO:0006415	translational termination	50/7096	104/18670	0.02269	0.1011	0.07535	MRPS6/C12orf65/MRPL35/MRPL45/CHCHD1/MRPL40/MRPS30/MRPL34/TRMT112/MRPS16/MRPS14/MRPL54/MRPL44/MRPL33/GSPT2/MRPL51/OXA1L/GFM2/ETF1/MTRF1L/MRPL49/MRPL3/MRPL42/DAP3/EIF5A/MRPS34/MRPL4/GADD45GIP1/APEH/MRPS33/MRPL20/MRPL46/MRPS18B/MRPL24/MRPL36/MRPS25/MRPS15/JMJD4/MRPL48/MTRF1/AURKAIP1/MRPL41/MRPL2/MRPS2/MRPS9/MRPL30/UPF1/MRPL1/MRRF/MRPS17	50
BP	GO:0046822	regulation of nucleocytoplasmic transport	50/7096	104/18670	0.02269	0.1011	0.07535	BARD1/NUP62/PTGS2/CHP1/FLNA/NUP214/KHDRBS1/RAN/GSK3B/HCLS1/MX2/TGFB1/RAB23/CD36/LEP/PRKCD/HYAL2/RBM4/IFI27/CDK5/SFN/SP100/EMD/ZPR1/IL1B/UBR5/DHX9/MDFIC/MAVS/NOLC1/RBM27/BMP4/NEDD4/PRKACA/PPP1CC/TXN/RIOK2/PSEN1/MDM2/MAPK1/TCF7L2/YWHAE/IFNG/CHP2/PKIA/XPO4/SMO/TARDBP/AAAS/CTDSPL2	50
BP	GO:0098732	macromolecule deacylation	50/7096	104/18670	0.02269	0.1011	0.07535	PINK1/SKI/ABHD13/BCL6/LYPLAL1/SIRT4/ABHD12/PER2/ABHD17C/MORF4L2/LYPLA2/TGFB1/SIN3A/MTA3/MSL3/ZBTB7B/VEGFA/SIRT7/HDAC11/MIER1/SMARCAD1/SIRT1/SFPQ/SIN3B/SUDS3/LRRK2/BRMS1L/HDAC10/HDAC2/AKAP8/HDAC7/MAPK8/NACC2/SIRT5/PRKD2/HDAC4/SPRED1/FRY/CAMK2D/ELK4/PRKAA1/IFNG/JDP2/TBL1X/HDAC5/BEX4/TADA3/MTA2/ATXN3L/BRMS1	50
BP	GO:0006778	porphyrin-containing compound metabolic process	21/7096	38/18670	0.02275	0.1011	0.07539	BLVRB/FECH/HMOX1/UROD/ALAD/ABCB6/CPOX/TMEM14C/SRRD/BDH2/CYP1A2/COX15/AMBP/IREB2/NFE2L1/RSAD1/EIF2AK1/ALAS1/SPTA1/SLC25A38/SLC25A39	21
BP	GO:0050716	positive regulation of interleukin-1 secretion	21/7096	38/18670	0.02275	0.1011	0.07539	NOD2/WNT5A/LILRA5/NLRP3/LILRA2/NLRP12/P2RX7/AIM2/TRIM16/PANX1/TLR4/HMGB1/CASP1/LGALS9/FZD5/TLR8/NLRP1/NLRP2/CCL19/HMGB4/IGHD	21
BP	GO:1900077	negative regulation of cellular response to insulin stimulus	21/7096	38/18670	0.02275	0.1011	0.07539	APPL2/SOCS3/TSC1/PTPN2/CISH/RELA/ENHO/PRKCD/NCK1/IL1B/GRB10/INPP5K/GPR21/KANK1/PRKAA1/PID1/SOCS1/SLA2/PRKCZ/PRKCQ/SOCS2	21
BP	GO:0006949	syncytium formation	30/7096	58/18670	0.02293	0.1011	0.07539	MYOF/SBNO2/CAPN2/FLOT1/IL4R/CXCL9/CXCL10/SH3PXD2A/CD53/PLEKHO1/DYRK1B/FLT3LG/EHD1/TYROBP/ERVW-1/MYH9/PTGFRN/MYOG/ERVFRD-1/ADAM12/NFATC2/ERCC1/CAV3/ADAM9/WNT1/DCSTAMP/TREM2/CACNA1H/CD109/MYF6	30
BP	GO:0051058	negative regulation of small GTPase mediated signal transduction	30/7096	58/18670	0.02293	0.1011	0.07539	STMN1/FBP1/NUP62/TIMP2/BCL6/EPHB2/ARHGAP25/KCTD10/HEG1/STMN3/RASA2/RASAL3/SH3BP1/FLCN/ARHGAP12/RASA3/SCAI/KANK1/SYNGAP1/RABGEF1/CD2AP/ITGA3/SPRY1/ABL2/SLIT2/SPRY2/STAMBP/RASAL1/MAPKAP1/MET	30
BP	GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors	30/7096	58/18670	0.02293	0.1011	0.07539	ITPRIP/PEA15/SKIL/TNFRSF10A/PMAIP1/TNFAIP3/FAS/HMOX1/TMC8/HGF/FEM1B/SP100/TNFSF10/CASP8/ARHGEF2/TRADD/RAF1/BMP5/SERPINE1/HMGB2/RFFL/TNFRSF10B/BRCA1/FADD/TRAF2/FAIM2/ZSWIM2/GPX1/FAIM/BMPR1B	30
BP	GO:0050727	regulation of inflammatory response	206/7096	485/18670	0.02295	0.1011	0.07539	KLF4/MYD88/IGF1/S100A9/S100A8/FPR2/NOD2/S100A12/CCR2/TLR2/PTGER4/NFKBIZ/METRNL/ACP5/ANXA1/IL1R2/BST1/CLEC7A/APPL2/GRN/SOCS3/SBNO2/LYN/CD55/FABP4/WNT5A/SOD1/IL17RA/PTPN2/PROS1/HCK/PTGS2/LILRA5/BCL6/NLRP3/PPARD/DUSP10/TNFAIP3/BIRC2/ABHD12/CTSC/NLRP12/CEBPB/MGST2/PLA2G7/JAK2/GSTP1/PTPRC/IL15/MGLL/A2M/ADAM8/CD59/TNF/SIGLEC10/NFKBIA/GPRC5B/NUPR1/GBP5/NFKB1/APOE/TICAM1/MIR142/RELA/CHID1/HGF/TNFAIP6/FFAR2/SOCS5/MAPK7/LEP/PSMA1/PRKCD/CFP/MAPK13/HYAL2/NAPEPLD/IL20RB/TLR4/CEBPA/ABR/HLA-E/IDO1/C5orf30/IL1B/NR1D2/AGER/CCL5/LDLR/DHX9/SPATA2/TNFRSF11A/TRADD/CLU/IL6ST/GPX4/IL1R1/MFHAS1/DNASE1/SERPING1/TTBK1/ADCY7/IL6/ADAMTS12/CDH5/CYLD/LRRK2/CD200R1/CR1/CD5L/CFHR4/BCR/ETS1/WFDC1/CST7/ATM/ZYX/VSIG4/SPHK1/AKNA/RPS19/C3AR1/SCGB1A1/GPSM3/ASH1L/ADORA2B/MMP9/MEFV/TNIP1/TGM2/SETD6/C2CD4B/SERPINE1/CD47/BIRC3/NR1H3/MMP3/FFAR4/ITGA2/OSM/CR2/TLR10/RHBDD3/C1R/RABGEF1/CNR2/ADA/NFE2L1/C1QBP/EGFR/IL18/PPARA/CLOCK/CMA1/TNFSF4/CFB/APOA1/TREM2/IL17B/C1QC/NLRP1/CPN1/RORA/TSLP/BAP1/SLC7A2/FANCD2/NLRX1/SUCNR1/RB1/TLR3/PIK3CG/SNX4/DUOXA1/LBP/IL12B/DROSHA/GPX1/FOXP1/TRPV4/C5AR2/TYRO3/FANCA/SNCA/CX3CL1/PDCD4/ABCD1/XIAP/FOXF1/CCR7/CFHR5/APPL1/PSMB4/CCL24/IL17RB/NR1H4/NLRC3/SLAMF8/IL23A/TLR6/C1QTNF3/IL17RC/MIR205/APCS/GHRL/C7	206
BP	GO:0050773	regulation of dendrite development	69/7096	149/18670	0.02303	0.1011	0.07539	SIPA1L1/ARF6/DNM3/CAMK1D/YWHAH/ALK/EZH2/APOE/GSK3B/ACTR2/LRP8/UBE3A/RAPGEF2/SS18L2/BCL11A/BAIAP2/ITSN1/CDK5/PLK2/PAFAH1B1/SRGAP2C/SEMA4D/MARK1/ANKRD27/CRK/BMP7/TMEM106B/CAPRIN1/KALRN/LRRK2/DCC/CYFIP1/ARC/CRTC1/ARF1/PDLIM5/HDAC2/BMP5/DISC1/NEDD4/CFL1/SHANK1/CPEB3/LPAR1/FSTL4/BHLHB9/DNM1L/NSMF/SS18L1/PREX1/PSEN1/FMR1/CHRNB2/CDC20/IL1RAPL1/KNDC1/CARM1/NR2E1/RELN/MTOR/RHOA/C21orf91/PARP6/ASAP1/LZTS1/SHANK3/ZMYND8/MEF2C/CAMK2B	69
BP	GO:0002363	alpha-beta T cell lineage commitment	12/7096	19/18670	0.02311	0.1011	0.07539	STAT6/STAT3/LY9/BATF/IL6/BCL2/IL12RB1/IL12B/TBX21/MTOR/RHOA/IL23A	12
BP	GO:0006534	cysteine metabolic process	12/7096	19/18670	0.02311	0.1011	0.07539	GCLM/AHCY/SLC7A11/APIP/MTRR/GCLC/ENOPH1/TST/MPST/CTH/AHCYL2/AHCYL1	12
BP	GO:0006555	methionine metabolic process	12/7096	19/18670	0.02311	0.1011	0.07539	SMS/ADI1/AHCY/MTR/APIP/MTRR/ENOPH1/MTAP/BHMT/AHCYL2/AHCYL1/MAT1A	12
BP	GO:0016074	snoRNA metabolic process	12/7096	19/18670	0.02311	0.1011	0.07539	NAF1/RNF113A/NOLC1/FBL/EXOSC2/GAR1/EXOSC3/FBLL1/EXOSC6/NUDT16/NOP10/EXOSC5	12
BP	GO:0016075	rRNA catabolic process	12/7096	19/18670	0.02311	0.1011	0.07539	DIS3L/DEDD2/SLFN13/XRN1/EXOSC2/EXOSC7/EXOSC9/EXOSC3/DROSHA/EXOSC6/EXOSC8/EXOSC5	12
BP	GO:0030150	protein import into mitochondrial matrix	12/7096	19/18670	0.02311	0.1011	0.07539	TIMM23B/DNAJC19/TIMM17A/TIMM21/GRPEL1/GRPEL2/TOMM40L/TOMM40/TOMM20/DNAJC15/TIMM50/TIMM44	12
BP	GO:0032011	ARF protein signal transduction	12/7096	19/18670	0.02311	0.1011	0.07539	CYTH4/CYTH1/ARFGEF1/IQSEC1/FBXO8/MAPRE2/IQSEC2/IQSEC3/PSD4/MAP4K4/ARFGAP1/PSD3	12
BP	GO:0032012	regulation of ARF protein signal transduction	12/7096	19/18670	0.02311	0.1011	0.07539	CYTH4/CYTH1/ARFGEF1/IQSEC1/FBXO8/MAPRE2/IQSEC2/IQSEC3/PSD4/MAP4K4/ARFGAP1/PSD3	12
BP	GO:0032930	positive regulation of superoxide anion generation	12/7096	19/18670	0.02311	0.1011	0.07539	ITGAM/FPR2/CLEC7A/SOD1/GNAI3/GSTP1/TGFB1/PRKCD/TYROBP/GNAI2/CYBA/EGFR	12
BP	GO:0034755	iron ion transmembrane transport	12/7096	19/18670	0.02311	0.1011	0.07539	SLC40A1/SLC11A1/MCOLN1/SLC25A37/STEAP4/HFE/SLC25A28/ISCU/STEAP3/HAMP/IFNG/ATP7A	12
BP	GO:0035728	response to hepatocyte growth factor	12/7096	19/18670	0.02311	0.1011	0.07539	APPL2/GCLM/LGMN/GAB1/RELA/HGF/GCLC/CREB1/CRK/ADAMTS12/NRP1/APPL1	12
BP	GO:0046641	positive regulation of alpha-beta T cell proliferation	12/7096	19/18670	0.02311	0.1011	0.07539	CCR2/CD55/PTPRC/HLA-E/RASAL3/LGALS9/EBI3/IL18/TNFSF4/IL12B/CD3E/IL23A	12
BP	GO:0098581	detection of external biotic stimulus	12/7096	19/18670	0.02311	0.1011	0.07539	NOD2/TLR1/TLR2/CLEC7A/LY96/SCARB1/TLR4/CD1D/PGLYRP4/TREM2/LBP/TLR6	12
BP	GO:0002467	germinal center formation	10/7096	15/18670	0.02321	0.1011	0.07539	BCL6/TNFAIP3/TNFSF13B/NFKB2/CXCL13/UNC13D/ADA/ADAM17/TNFRSF13C/MEF2C	10
BP	GO:0019321	pentose metabolic process	10/7096	15/18670	0.02321	0.1011	0.07539	TALDO1/RPE/TKT/DHDH/RPIA/FGGY/G6PD/NUDT5/PGD/RBKS	10
BP	GO:0046838	phosphorylated carbohydrate dephosphorylation	10/7096	15/18670	0.02321	0.1011	0.07539	INPP1/SYNJ1/SYNJ2/OCRL/INPP5K/IMPA2/MTMR2/G6PC/INPP5A/IMPA1	10
BP	GO:0048070	regulation of developmental pigmentation	10/7096	15/18670	0.02321	0.1011	0.07539	HPS4/KITLG/ZEB2/VPS33A/BLOC1S6/BCL2L11/BCL2/BAX/GNA11/ADAMTS9	10
BP	GO:0048569	post-embryonic animal organ development	10/7096	15/18670	0.02321	0.1011	0.07539	KLF4/LDHA/VEGFA/BCL2L11/BAX/ERCC1/FZD5/BCL11B/MFAP2/BAK1	10
BP	GO:0051044	positive regulation of membrane protein ectodomain proteolysis	10/7096	15/18670	0.02321	0.1011	0.07539	ADAM8/TNF/APOE/IL1B/FURIN/SNX33/ADAM9/IFNG/SNX9/PACSIN3	10
BP	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	10/7096	15/18670	0.02321	0.1011	0.07539	NOD2/TLR2/NAMPT/STAT1/JAK2/TLR4/LRRK2/FCER2/MAP2K4/IFNG	10
BP	GO:0060339	negative regulation of type I interferon-mediated signaling pathway	10/7096	15/18670	0.02321	0.1011	0.07539	PTPN2/NLRC5/YTHDF3/METTL3/CACTIN/SAMHD1/MMP12/CNOT7/MUL1/ADAR	10
BP	GO:0071801	regulation of podosome assembly	10/7096	15/18670	0.02321	0.1011	0.07539	HCK/TNF/KIF9/ARHGEF2/LCP1/FSCN1/MSN/RHOA/ASAP1/MAPK9	10
BP	GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	79/7096	173/18670	0.02327	0.1011	0.07539	NOD2/LYN/WNT5A/ZNF622/SH3RF1/DVL2/TNF/ERCC6/ZEB2/MAP3K4/HMGCR/SLAMF1/TAOK3/GADD45B/PAK1/MAP4K5/PTK2B/LEP/ROR2/TRAF6/NCF1/TLR4/TPD52L1/BMP2/VEGFA/HRAS/IL1B/SEMA4C/AGER/MAP3K12/RASGRP1/SDCBP/MDFIC/HMGB1/TNFRSF11A/IL1RN/MFHAS1/DUSP19/MAP4K2/RELL2/SPHK1/EDAR/MAP3K6/MAP4K1/MLKL/MAP3K11/SH3RF3/FZD5/BIRC7/MAP3K5/PLCB1/EIF2AK2/MUL1/TRAF2/FZD4/MAP2K4/MAP3K13/ANKRD6/TLR3/FZD7/TRPV4/APP/ERN1/PDCD10/CCL19/TIRAP/TRAF4/WNT7A/CCR7/PRMT1/IL26/DAXX/SERPINF2/TLR6/FZD10/NRK/SASH1/IL37/MAP3K9	79
BP	GO:0042254	ribosome biogenesis	130/7096	297/18670	0.02327	0.1011	0.07539	DDX21/TSC1/ZNF622/LYAR/GNL2/RPP38/RAN/TSR1/EIF6/ZNF658/GTPBP4/WDR46/UTP14A/ISG20/ISG20L2/XRN2/NAF1/DDX49/TFB1M/KRI1/NPM1/TRMT112/KRR1/ZNF593/TRMT61B/RPP25/RPUSD2/SIRT1/ABT1/RPS24/WDR74/NOLC1/MRTO4/NAT10/DDX3X/NOP16/DDX24/RPS21/THUMPD1/AATF/RPS9/FBL/RRP7A/RPS19/SUV39H1/MYBBP1A/NHP2/LAS1L/UTP15/NIP7/EXOSC2/NUP88/NOC2L/GAR1/FTSJ3/RPF2/FDXACB1/RNASEL/DIMT1/ZCCHC4/WDR36/EXOSC7/RCL1/WDR75/PWP1/METTL15/DCAF13/C1QBP/NOL8/GTF3A/LTV1/RRP15/RIOK2/NOL10/SART1/RIOK3/ERI3/RPP40/MPHOSPH6/AAMP/TEX10/MRM1/RPL24/EIF2A/IMP4/MRPL20/RPS16/WBP11/EXOSC9/NOC4L/DDX18/MRPL36/EXOSC3/DDX27/GNL3L/RPL7L1/CUL4B/FAM207A/RPL26L1/FBLL1/NSUN5P1/POP7/REXO4/TSR2/DROSHA/MDN1/DDX54/DDX10/EXOSC6/MPV17L2/MRPS2/EXOSC8/MRPS9/ZNHIT6/NUDT16/RPL3L/NOP10/C1D/CEBPZ/UTP3/RRS1/ESF1/PA2G4/NOM1/EXOSC5/DDX31/DDX52/NWD2/MRPL1/RPL10A	130
BP	GO:0006595	polyamine metabolic process	11/7096	17/18670	0.02335	0.1011	0.07539	SMS/OAZ2/SAT1/OAZ3/ODC1/HDAC10/AZIN1/SRM/AZIN2/AGMAT/DHPS	11
BP	GO:0015693	magnesium ion transport	11/7096	17/18670	0.02335	0.1011	0.07539	MRS2/NIPA2/CNNM2/NIPAL4/CNNM4/NIPA1/ZDHHC13/SLC41A1/TUSC3/NIPAL3/MMGT1	11
BP	GO:0035518	histone H2A monoubiquitination	11/7096	17/18670	0.02335	0.1011	0.07539	RYBP/TRIM37/PCGF2/DDB1/PCGF1/PCGF3/BCOR/KDM2B/RING1/DDB2/CUL4B	11
BP	GO:0045072	regulation of interferon-gamma biosynthetic process	11/7096	17/18670	0.02335	0.1011	0.07539	CLEC7A/CEBPG/LILRB1/INHBA/EBI3/CD276/TLR8/TLR3/INHA/TNFRSF13C/IL12B	11
BP	GO:0048532	anatomical structure arrangement	11/7096	17/18670	0.02335	0.1011	0.07539	DLL1/HSPA5/EGR2/BMPR1A/NRP1/NRP2/DAB1/KCNA2/HOXB1/PLXNA3/KIF14	11
BP	GO:0055070	copper ion homeostasis	11/7096	17/18670	0.02335	0.1011	0.07539	SCO2/SLC31A2/ATOX1/COX19/ATP7B/ARF1/CUTC/COMMD1/ATP7A/APP/XIAP	11
BP	GO:0060644	mammary gland epithelial cell differentiation	11/7096	17/18670	0.02335	0.1011	0.07539	CEBPB/HIF1A/LATS1/ZNF703/ID2/ELF5/MGMT/FOXF1/SMO/LBH/PTCH1	11
BP	GO:0070242	thymocyte apoptotic process	11/7096	17/18670	0.02335	0.1011	0.07539	WNT5A/ADAM8/HIF1A/NFKBID/DFFA/BCL2L11/BMP4/BAX/ADA/PTCRA/BAK1	11
BP	GO:1902683	regulation of receptor localization to synapse	11/7096	17/18670	0.02335	0.1011	0.07539	STX7/GRIPAP1/HRAS/RAP1A/TYROBP/NPTN/GRASP/IQSEC2/PRKCZ/GPC4/DAG1	11
BP	GO:0009064	glutamine family amino acid metabolic process	37/7096	74/18670	0.02339	0.1012	0.07548	ASRGL1/ATP2B4/GCLM/ARG2/SIRT4/SLC7A11/HAL/DDAH2/FAH/ALDH18A1/GMPS/SLC7A7/NAGS/CTPS2/GCLC/ALDH4A1/ASNSD1/GLUD1/DAO/ADHFE1/ALDH5A1/SLC25A12/GLUD2/ASNS/PPAT/GLS/GOT2/GFPT1/FPGS/CTPS1/CAD/AMDHD1/GFPT2/ATCAY/AGMAT/PHGDH/NR1H4	37
BP	GO:0046467	membrane lipid biosynthetic process	66/7096	142/18670	0.02361	0.1021	0.07614	ASAH1/ALDH3A2/SGMS2/CSNK1G2/PIGV/PIGP/CERS2/P2RX7/DEGS1/TNF/ELOVL5/PIGK/CLN8/SCCPDH/PIGN/SGPL1/PRKCD/SGPP2/B4GALT6/CERS5/B3GNT5/SPTLC2/SAMD8/ST3GAL2/PIGF/VAPB/ELOVL7/CERS4/PIGB/DPM1/GPAA1/ORMDL2/SPHK1/PIGM/P2RX1/ORMDL3/PRKD2/MPPE1/PPM1L/SGMS1/B4GALNT1/PIGQ/GAL3ST4/B4GALT5/PIGO/UGCG/ST8SIA4/PIGH/AGK/ST6GALNAC5/ACER3/PRKAA1/DPM3/KDSR/PLA2G6/PIGT/ST6GALNAC3/SMPD1/ST6GALNAC6/ELOVL6/SMPD2/PGAP3/ST8SIA1/ST3GAL5/PGAP1/DEGS2	66
BP	GO:0001510	RNA methylation	40/7096	81/18670	0.02393	0.1033	0.07701	TRMT6/MEPCE/FTSJ1/METTL14/TRMT5/TRMT1/TYW3/METTL3/TFB1M/BCDIN3D/LCMT2/TRMT112/TRMT61B/NSUN2/TRMT1L/CBLL1/FBL/METTL1/METTL8/HSD17B10/FTSJ3/FDXACB1/DIMT1/CMTR1/ZCCHC4/WDR4/ALKBH8/THUMPD2/TRMT11/TGS1/METTL15/THUMPD3/MRM1/FBLL1/NSUN5P1/CMTR2/MTO1/TRMT10C/GTPBP3/NSUN6	40
BP	GO:0016126	sterol biosynthetic process	40/7096	81/18670	0.02393	0.1033	0.07701	POR/SOD1/NFYC/GPAM/CYB5R1/FAXDC2/SQLE/RAN/APOE/HMGCR/HMGCS1/SCD/ERLIN1/CNBP/ACLY/ERLIN2/FDPS/ACACB/G6PD/FGF1/ARV1/TM7SF2/APOA5/MSMO1/IDI1/PRKAG2/SCAP/ABCG1/SC5D/CH25H/SREBF2/CYB5R3/INSIG1/ACAA2/PRKAA1/APOA1/MBTPS2/ELOVL6/MBTPS1/KPNB1	40
BP	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	40/7096	81/18670	0.02393	0.1033	0.07701	CBFA2T3/SMAD7/KEAP1/DDRGK1/BCAP31/GSK3B/RNF19B/SGTA/ZFAND2A/SOCS5/CSNK1D/RNF217/CEBPA/PLK2/ANKIB1/GCLC/CLU/LRRK2/SUMO1/HSPBP1/CSNK1A1/CSNK1E/ARIH2/PLK3/UBQLN2/TRIB2/BBS7/DET1/NKD2/KLHL40/STUB1/NFE2L2/DVL1/PSEN1/MDM2/VCP/AURKA/RBX1/CHFR/MAPK9	40
BP	GO:0006007	glucose catabolic process	20/7096	36/18670	0.02423	0.1043	0.07774	HK3/PGK1/PFKM/PFKP/GAPDH/PGAM1/LRP5/PKM/TPI1/ALDOC/ENO1/ALDOA/GPI/SLC25A12/FOXK2/PFKFB2/ENO2/BAD/ADPGK/PFKL	20
BP	GO:0009112	nucleobase metabolic process	20/7096	36/18670	0.02423	0.1043	0.07774	TYMP/ACPP/ALDH6A1/GMPS/PAICS/CTPS2/DPYD/CMPK1/GMPR2/PRPS1/PPAT/TYMS/ADA/SHMT1/MAPK1/CTPS1/CAD/CDA/MTOR/AOX1	20
BP	GO:0046627	negative regulation of insulin receptor signaling pathway	20/7096	36/18670	0.02423	0.1043	0.07774	SOCS3/TSC1/PTPN2/CISH/RELA/ENHO/PRKCD/NCK1/IL1B/GRB10/INPP5K/GPR21/KANK1/PRKAA1/PID1/SOCS1/SLA2/PRKCZ/PRKCQ/SOCS2	20
BP	GO:0002204	somatic recombination of immunoglobulin genes involved in immune response	25/7096	47/18670	0.02427	0.1043	0.07774	IL27RA/MAD2L2/STAT6/BCL6/CD40/PTPRC/BATF/TGFB1/UNG/SWAP70/MLH1/PARP3/ERCC1/CLCF1/CCR6/LIG4/TFRC/TNFSF4/EXO1/EXOSC3/TBX21/APLF/EXOSC6/PAXIP1/ATAD5	25
BP	GO:0002208	somatic diversification of immunoglobulins involved in immune response	25/7096	47/18670	0.02427	0.1043	0.07774	IL27RA/MAD2L2/STAT6/BCL6/CD40/PTPRC/BATF/TGFB1/UNG/SWAP70/MLH1/PARP3/ERCC1/CLCF1/CCR6/LIG4/TFRC/TNFSF4/EXO1/EXOSC3/TBX21/APLF/EXOSC6/PAXIP1/ATAD5	25
BP	GO:0045190	isotype switching	25/7096	47/18670	0.02427	0.1043	0.07774	IL27RA/MAD2L2/STAT6/BCL6/CD40/PTPRC/BATF/TGFB1/UNG/SWAP70/MLH1/PARP3/ERCC1/CLCF1/CCR6/LIG4/TFRC/TNFSF4/EXO1/EXOSC3/TBX21/APLF/EXOSC6/PAXIP1/ATAD5	25
BP	GO:2001239	regulation of extrinsic apoptotic signaling pathway in absence of ligand	25/7096	47/18670	0.02427	0.1043	0.07774	SRPX/FYN/STRADB/EYA3/TNF/CTNNA1/MAPK7/MCL1/HTRA2/IL1B/IL7/WWOX/BCL2/IL1A/INHBA/UNC5B/PPP1CA/PPP2R1B/COL2A1/ZC3HC1/EYA4/RET/MAP2K5/TERT/CX3CL1	25
BP	GO:2000379	positive regulation of reactive oxygen species metabolic process	49/7096	102/18670	0.0243	0.1043	0.07778	KLF4/ITGAM/FPR2/KLF2/CDKN1A/CLEC7A/SOD1/GNAI3/PTGS2/RNF41/JAK2/GSTP1/TNF/DDAH2/AKR1C3/PKD2/TICAM1/TGFB1/CD36/PTK2B/LEP/PRKCD/INSR/HBB/PTX3/TLR4/IL1B/AIF1/CLU/TYROBP/PDGFB/DNM2/GNAI2/HDAC4/GRB2/CYBA/AGXT2/NFE2L2/EGFR/PID1/IFNG/HSP90AB1/DUOXA1/MTOR/SNCA/NNT/RAB27A/TLR6/FOXO3	49
BP	GO:0110020	regulation of actomyosin structure organization	46/7096	95/18670	0.02434	0.1044	0.07787	S100A10/PTGER4/STMN1/FHOD1/TSC1/ARAP1/SORBS3/RHOC/S1PR1/RGCC/AKAP13/SLC9A1/ARHGEF10L/EVL/PFN1/PAK1/ABL1/PPM1F/MKKS/RAC1/ARHGAP6/BBS4/LIMCH1/NRP1/TPM1/INPP5K/CD47/LPAR1/PXN/CLASP2/CAV3/APOA1/TGFB3/SYNPO2L/TACSTD2/TMEFF2/MTOR/RHOA/ITGB1BP1/MET/WAS/ROCK2/ASAP3/SERPINF2/ALMS1/MEF2C	46
BP	GO:0050768	negative regulation of neurogenesis	129/7096	295/18670	0.02451	0.1051	0.07837	RTN4R/DPYSL3/DLL1/APPL2/ARF6/SKI/DNM3/WNT5A/DENND5A/TSC1/HMG20A/STAT3/SEMA4B/VIM/LRIG2/SPP1/DUSP10/RNF10/CIB1/ULK2/YWHAH/CERS2/TNF/EPHB2/ARHGDIA/IFRD1/APOE/GSK3B/PTPRO/NOTCH3/MIB1/UBE3A/TGFB1/DGUOK/CTNNA1/RAPGEF2/PCM1/BCL11A/NRG1/MBD1/SEMA4A/ASCL2/DTX1/CDK5/PLK2/TRAK2/PAFAH1B1/CTSZ/CDK5RAP2/SRGAP2C/IL1B/GDI1/SEMA4C/LDLR/ARHGEF2/PAQR3/SEMA4D/LRP1/HEY1/TRIM11/BMP7/RAB29/IL6/LRRK2/DCC/IDH2/ASPM/PTK2/DICER1/DIXDC1/SEMA6B/SRGAP2/HDAC2/BMPR1A/NRP1/SEMA3B/HOOK3/ID2/CTDSP1/KCTD11/CNTN4/KANK1/LGALS1/SYNGAP1/DAB1/INPP5F/RTN4RL1/PITX3/SEMA5A/LPAR1/HES1/FSTL4/CALR/CNTF/TLX3/SLIT2/PSEN1/MDM2/SEMA5B/RTN4RL2/EIF4E/RUFY3/PLXNA3/SPOCK1/NR2F1/CARM1/TERT/MEIS1/EIF2AK4/NR2E1/SYT4/MAP4K4/RHOA/TRPV4/APP/RTN4/CX3CL1/BAG5/KREMEN1/ASAP1/LMX1A/FGF13/LRP4/WNT7A/EIF4ENIF1/DAAM2/FOXO3/TRIM46/MIR146A	129
BP	GO:0000768	syncytium formation by plasma membrane fusion	29/7096	56/18670	0.02461	0.1052	0.07841	MYOF/SBNO2/CAPN2/FLOT1/IL4R/CXCL9/CXCL10/SH3PXD2A/CD53/PLEKHO1/DYRK1B/FLT3LG/EHD1/TYROBP/ERVW-1/MYH9/PTGFRN/MYOG/ERVFRD-1/ADAM12/NFATC2/CAV3/ADAM9/WNT1/DCSTAMP/TREM2/CACNA1H/CD109/MYF6	29
BP	GO:0044784	metaphase/anaphase transition of cell cycle	29/7096	56/18670	0.02461	0.1052	0.07841	DUSP1/MAD2L2/DYNC1LI1/SPDL1/CENPE/KLHL22/CDK5RAP2/NSMCE2/CDC23/ESPL1/ZNF207/LCMT1/ATM/ANAPC5/BUB3/NDC80/GEN1/ZW10/MOS/CDC26/RIOK2/DLGAP5/ANAPC4/CDC27/CDC20/PCID2/RB1/ANAPC11/IK	29
BP	GO:0048488	synaptic vesicle endocytosis	29/7096	56/18670	0.02461	0.1052	0.07841	ARF6/DNM3/SYT11/POTEKP/FCHO2/DENND1A/ACTB/PPP3CB/SYNJ1/ITSN1/CDK5/OPHN1/LRRK2/DNAJC6/TOR1A/SH3GL1/DNM1/DNM2/KIAA1107/CANX/DNM1L/SYT1/SYT2/SYT5/SNCA/PICALM/NLGN2/KIAA1109/AMPH	29
BP	GO:0140238	presynaptic endocytosis	29/7096	56/18670	0.02461	0.1052	0.07841	ARF6/DNM3/SYT11/POTEKP/FCHO2/DENND1A/ACTB/PPP3CB/SYNJ1/ITSN1/CDK5/OPHN1/LRRK2/DNAJC6/TOR1A/SH3GL1/DNM1/DNM2/KIAA1107/CANX/DNM1L/SYT1/SYT2/SYT5/SNCA/PICALM/NLGN2/KIAA1109/AMPH	29
BP	GO:0140253	cell-cell fusion	29/7096	56/18670	0.02461	0.1052	0.07841	MYOF/SBNO2/CAPN2/FLOT1/IL4R/CXCL9/CXCL10/SH3PXD2A/CD53/PLEKHO1/DYRK1B/FLT3LG/EHD1/TYROBP/ERVW-1/MYH9/PTGFRN/MYOG/ERVFRD-1/ADAM12/NFATC2/CAV3/ADAM9/WNT1/DCSTAMP/TREM2/CACNA1H/CD109/MYF6	29
BP	GO:0035023	regulation of Rho protein signal transduction	65/7096	140/18670	0.02517	0.1074	0.08011	RTN4R/STMN1/CDC42SE1/ARHGEF18/PLEKHG2/SPATA13/MYO9B/BCL6/ARHGEF3/FLOT1/ALS2/P2RY8/FGD6/FGD5/AKAP13/ARHGDIA/APOE/ARHGEF10L/ARHGEF40/ARRB1/KCTD10/HEG1/CDC42SE2/ITSN1/ABR/NET1/ARHGDIB/ABL1/ARHGEF6/OPHN1/ABCA1/ARHGEF2/RAF1/RAC1/LPAR6/KALRN/FLCN/BCR/SCAI/NRP1/KANK1/GPR18/OBSCN/ITGA3/LPAR1/F2R/RASGRF1/VAV1/ABL2/PREX1/ITSN2/GPR35/APOA1/ARHGEF37/FGD3/ARHGEF17/SYNPO2L/FGD4/EPS8L2/P2RY10/MET/ARHGEF4/GPR20/MCF2L/ARHGEF9	65
BP	GO:0035725	sodium ion transmembrane transport	65/7096	140/18670	0.02517	0.1074	0.08011	SLC8A1/PKD2L1/ATP2B4/SLC9A9/ATP1A1/TPCN1/KLHL24/CHP1/NETO2/ACTN4/YWHAH/SLC9A1/FXYD5/TESC/PKD2/FXYD6/SCN1B/ATP4A/CNNM4/DMD/TRPM4/TRPM2/ATP1B2/SLC28A3/SLC9A8/SLC9A7/ATP1B3/ARF1/SLC12A2/HCN4/FXYD1/DNM2/NEDD4/ATP1B1/RANGRF/ABCB11/SCN2B/SLC20A1/SLC41A1/COMMD1/CAMK2D/CAV3/SLC20A2/SLC8A2/SLC17A4/FXYD7/SLC24A4/FXYD2/SCN8A/KIF5B/SLC12A1/SNTA1/SLC5A10/SCN9A/SCN3A/SLC9B2/SLC24A2/HCN1/FXYD3/ATP1A2/SLC8A3/SLC4A11/SLC9C2/ATP12A/WNK2	65
BP	GO:0048638	regulation of developmental growth	150/7096	347/18670	0.02526	0.1077	0.08032	IGF1/RTN4R/FN1/EZR/DLL1/CDKN1A/DPYSL2/PLS1/DUSP6/RBPJ/POR/WNT5A/SOD1/STAT3/SEMA4B/PIM1/SPP1/RAB11A/PPARD/DUSP10/PLAC8/ULK2/RGS2/LGMN/IFRD1/APOE/GSK3B/PLAA/CXCL12/CDK4/TWF2/SIN3A/PAK1/SGPL1/MEGF8/LEP/BCL11A/SRF/INSR/LATS1/SEMA4A/HTRA2/ADRB1/PARP2/VEGFA/CDK5/TNFRSF12A/ABL1/PAFAH1B1/STAT5A/GDI1/ATRN/SEMA4C/SEMA4D/ACACB/LRP1/CREB1/BBS2/IL7/SAV1/BASP1/AFG3L2/MKKS/CTDP1/DCC/G6PD/CYFIP1/MBD5/SERP1/PTK2/ARX/BBS4/SEMA6B/BCL2L11/FTO/BMPR1A/NRP1/DISC1/SEMA3B/BCL2/DNM2/BMP4/L1CAM/GPR21/CDKN1B/YY1/LPAR3/IST1/ADRB2/NDEL1/GAMT/OLFM1/WDR36/KCNK2/YBX3/SEMA5A/FSTL4/ZMPSTE24/WWC2/HLX/MYOZ1/PLCB1/MUL1/PPARA/CAV3/HEY2/ITSN2/HAMP/SEMA5B/MAPK1/RASAL1/HNF1B/CAPN3/MAP3K13/RUFY3/PLXNA3/MAPK11/LATS2/SYT1/CPNE9/PIN1/SYT2/CARM1/MEIS1/SYT4/MTOR/APP/GHRH/RTN4/CRABP2/RIMS2/FGF13/GHR/PPIB/SOCS2/GJA1/SMO/WT1/RBP4/TLL2/PTCH1/MACF1/WWC1/TRPV2/GHRL/MEF2C/TRIM46/NRK/BMPR2/GDF5	150
BP	GO:0071333	cellular response to glucose stimulus	62/7096	133/18670	0.02577	0.1096	0.08172	TRA2B/GCLM/ENY2/HMGCR/LRP5/PPP3CB/SIN3A/AACS/UNC13B/FIS1/ARRB1/HIF1A/PIM3/PCK2/SRF/IGF1R/GCLC/AGER/C2CD2L/RAP1A/MPC2/LRP1/RAF1/TRPM4/RAC1/IRS2/ZNF236/PPARGC1A/KLF7/SRI/OXCT1/POLG/GPR27/NME1/PRKACA/LGALS1/PDX1/CYBA/PTPRN2/HMGN3/CMA1/PRKAA1/BAD/PLA2G6/KIF5B/MEN1/WDR35/ZBTB20/NDUFAF2/MAP4K4/ERN1/SLC9B2/SOX4/SIDT2/GCG/ENDOG/NR1H4/STXBP4/FOXO3/GHRL/MIR146A/PHPT1	62
BP	GO:0010574	regulation of vascular endothelial growth factor production	19/7096	34/18670	0.02578	0.1096	0.08172	CCR2/PTGS2/ATF4/NDRG2/TGFB1/CYP1B1/HIF1A/IL1B/IL6ST/IL6/SULF2/C3AR1/HPSE/ADORA2B/IL1A/ARNT/BRCA1/RORA/MIR146A	19
BP	GO:0034205	amyloid-beta formation	19/7096	34/18670	0.02578	0.1096	0.08172	IGF1/TNF/PSENEN/APOE/CASP3/TMED10/CLU/ABCG1/ABCA7/IFNGR1/PSEN1/IFNG/PIN1/APP/GSAP/APH1A/PICALM/ROCK2/BIN1	19
BP	GO:0042533	tumor necrosis factor biosynthetic process	19/7096	34/18670	0.02578	0.1096	0.08172	CCR2/TLR1/CX3CR1/CLEC7A/AZU1/JAK2/LILRB1/HSPB1/TLR4/AGER/UBE2J1/TYROBP/MAPKAPK2/CYBB/PSEN1/IFNG/LBP/APP/GHRL	19
BP	GO:0042534	regulation of tumor necrosis factor biosynthetic process	19/7096	34/18670	0.02578	0.1096	0.08172	CCR2/TLR1/CX3CR1/CLEC7A/AZU1/JAK2/LILRB1/HSPB1/TLR4/AGER/UBE2J1/TYROBP/MAPKAPK2/CYBB/PSEN1/IFNG/LBP/APP/GHRL	19
BP	GO:0006399	tRNA metabolic process	87/7096	193/18670	0.02584	0.1098	0.08187	TRMT6/SEPHS2/PARS2/DPH3/PPA1/ALKBH1/FTSJ1/TPRKB/OSGEPL1/FAM98B/SEPSECS/ELP4/RPP38/NARS2/TRMT5/TRMT1/EEF1E1/TYW3/AIMP1/BCDIN3D/DUS2/LCMT2/LARS2/TRMT112/PPA2/POLR2L/TRMT61B/RPP25/ELAC1/NSUN2/DALRD3/SLFN13/TRMT1L/DTD1/RPP14/PUS1/TP53RK/CLP1/NAT10/OSGEP/PSTK/THUMPD1/IARS2/METTL1/AIMP2/ELP3/METTL8/EXOSC2/HSD17B10/DDX1/QTRT1/WDR4/ALKBH8/EXOSC7/THUMPD2/MOCS3/TRMT11/THUMPD3/SSB/MARS2/RPP40/ELP2/GTF3C3/HARS2/EXOSC9/MTFMT/EXOSC3/YARS2/RPPH1/DARS2/POP7/DTD2/QRSL1/ADAT2/MTO1/C2orf49/CPSF1/DUS1L/TRMT10C/PUS7/GTPBP3/EXOSC8/NSUN6/AARS2/POLR3K/ADAT1/WARS2	87
BP	GO:0048013	ephrin receptor signaling pathway	42/7096	86/18670	0.02598	0.1101	0.08205	FYN/SIPA1L1/LYN/RBPJ/APH1B/EPHB2/PSENEN/ACTR2/ACTB/PAK1/ITSN1/NCK1/HRAS/ARPC1A/SDCBP/EFNB1/CRK/RAC1/ARPC1B/KALRN/EPHA8/EPHA10/PSEN2/PTK2/DNM1/AP2A2/MMP9/AP2S1/ACTR3/AP2A1/PSEN1/SS18/ARPC4/EPHB1/ARPC2/MMP2/AP2M1/RHOA/EFNA2/APH1A/ROCK2/EFNA3	42
BP	GO:0002833	positive regulation of response to biotic stimulus	24/7096	45/18670	0.026	0.1101	0.08205	GRN/MIF/LY96/LY86/DDX60/CD226/UNC13B/TRAF6/FBXO38/SIGLEC16/PUM2/ANKRD17/PVR/CD274/CYBA/CRTAM/HAVCR2/HRG/TRIM15/IL12B/OPTN/ZCCHC3/PRKCA/SASH1	24
BP	GO:0044275	cellular carbohydrate catabolic process	24/7096	45/18670	0.026	0.1101	0.08205	ENOSF1/MANBA/MGAM/GK/AGL/PGAM1/TPI1/PPP1R3D/PHKB/PHKG1/GUSB/PGM2/GK5/PPP1R3B/SORD/PPP1CA/GAA/PYGM/PGD/PPP1CB/PYGL/ABHD10/TREH/G6PC	24
BP	GO:0006893	Golgi to plasma membrane transport	32/7096	63/18670	0.026	0.1101	0.08205	CSK/GGA2/TRIM23/VAMP5/SYS1/EXOC6B/RAB31/EXOC1/ARF4/ARF5/GOPC/VAMP3/C16orf70/CNST/BBS2/PREPL/SPTBN1/ARF1/GOLPH3L/DNM2/CCDC93/KIF13A/ARFRP1/COMMD1/RABEP1/EXOC4/LLGL1/OPTN/ARF3/RAB26/MACF1/EXOC2	32
BP	GO:0042982	amyloid precursor protein metabolic process	32/7096	63/18670	0.026	0.1101	0.08205	IGF1/LYN/AGO2/SOAT1/TNF/PSENEN/APOE/ITM2B/CASP3/TMED10/CLN3/AGER/ITM2A/CLU/FLOT2/BACE2/PSEN2/AATF/ABCG1/ABCA7/IFNGR1/PSEN1/NECAB3/IFNG/PIN1/APP/GSAP/APH1A/PICALM/ROCK2/BIN1/EFNA3	32
BP	GO:0046637	regulation of alpha-beta T cell differentiation	32/7096	63/18670	0.026	0.1101	0.08205	PNP/NFKBIZ/ANXA1/BCL6/NLRP3/SH3RF1/SMAD7/IL4R/CBFB/SOCS5/ZBTB7B/NFKBID/HMGB1/IL12RB1/LGALS9/ADA/HLX/IL18/AP3B1/TNFSF4/SOCS1/IFNG/IL12B/PRKCZ/CD80/TBX21/RHOA/CD83/CCL19/MALT1/ZBTB16/IL23A	32
BP	GO:0006476	protein deacetylation	45/7096	93/18670	0.02608	0.1103	0.08224	PINK1/SKI/BCL6/SIRT4/PER2/MORF4L2/TGFB1/SIN3A/MTA3/MSL3/ZBTB7B/VEGFA/SIRT7/HDAC11/MIER1/SMARCAD1/SIRT1/SFPQ/SIN3B/SUDS3/LRRK2/BRMS1L/HDAC10/HDAC2/AKAP8/HDAC7/MAPK8/NACC2/SIRT5/PRKD2/HDAC4/SPRED1/FRY/CAMK2D/ELK4/PRKAA1/IFNG/JDP2/TBL1X/HDAC5/BEX4/TADA3/MTA2/ATXN3L/BRMS1	45
BP	GO:0022408	negative regulation of cell-cell adhesion	82/7096	181/18670	0.02612	0.1104	0.08228	KLF4/MYADM/PTPN6/LILRB2/ANXA1/MAD2L2/IRF1/ARG2/GPNMB/PTPN2/TNFRSF14/BCL6/SMAD7/MBP/FGL2/IL4R/CEBPB/RGCC/CBFB/JAK2/HFE/CD74/TNFRSF21/FXYD5/LILRB1/CXCL12/DUSP3/TGFB1/RDX/GTPBP4/SOCS5/MAPK7/SWAP70/PRKCD/METTL3/IL20RB/PTPN22/ZBTB7B/SOCS6/BMP2/VEGFA/DTX1/CASP3/ABL1/IDO1/NFKBID/HMGB1/IL1RN/PPM1F/HLA-G/CTLA4/GLMN/PTK2/TIGIT/VSIG4/AKNA/SCGB1A1/PDCD1LG2/NRARP/ZNF703/BMP4/LAG3/CD300A/CD274/LGALS9/LAX1/BTN2A2/HLX/CDSN/PPARA/TNFSF4/WNT1/PAG1/APOA1/SOCS1/HAVCR2/MAP2K5/CD80/TBX21/TRPV4/TWSG1/MIR146A	82
BP	GO:0045926	negative regulation of growth	110/7096	249/18670	0.02613	0.1104	0.08228	RTN4R/CDKN2D/CDKN1A/FBP1/NOTCH2/PPP2CA/OSGIN1/WNT5A/SEMA4B/SPP1/BCL6/PPARD/DUSP10/PLAC8/ADIPOR1/ULK2/RGS2/LGMN/IFRD1/SH3BP4/PSRC1/TGFB1/HIF1A/PAK1/OSGIN2/BCL11A/ADAM15/HYAL2/NDUFS3/SEMA4A/ADRB1/RBBP7/CDK5/ENO1/NDRG3/PTK6/SEMA4C/PML/SEMA4D/BBS2/SIRT1/SAV1/CDKN2AIP/CTDP1/ACVR1B/DCC/G6PD/FLCN/DDX3X/PTK2/WFDC1/SEMA6B/ING1/ALOX15B/BTG1/NRP1/SEMA3B/BCL2/BMP4/EI24/CDKN1B/CDKN2C/YY1/ADRB2/FHL1/INHBA/ST20/KCNK2/SEMA5A/FSTL4/WWC2/SERTAD2/MYOZ1/MUL1/PPARA/CAV3/SLIT2/ADIPOR2/TCHP/SEMA5B/DCSTAMP/CYP27B1/DCUN1D3/PLXNA3/MAPK11/NAIF1/HRG/BDKRB1/ING4/JADE1/MSX1/MEIS1/CDA/RTN4/PNPT1/FGF13/DCBLD2/SOCS2/GJA1/SESN2/WT1/RBP4/TLL2/PTCH1/WWC1/TRIM46/PTPRJ/PRDM11/BMPR2/SLIT3	110
BP	GO:0000077	DNA damage checkpoint	67/7096	145/18670	0.02615	0.1104	0.08229	PEA15/CDKN1A/FBXO6/RNASEH2B/RGCC/HUS1B/GIGYF2/BTG2/DOT1L/RAD1/TAOK3/ZNF830/FEM1B/ETAA1/USP28/UIMC1/INTS7/SYF2/PLK2/SFN/DONSON/PML/TIPIN/CCND1/RHNO1/ATM/TNKS1BP1/MUC1/PLK3/RAD17/PCNA/BAX/CRADD/CASP2/RFWD3/CDKN1B/CNOT4/PLAGL1/ARID3A/FOXO4/THOC5/DTL/CEP63/FBXO4/E2F4/BRCA1/CNOT7/GML/ATR/CLOCK/MDM2/CLSPN/RBL2/RAD9A/CNOT10/PRPF19/CARM1/EIF2AK4/HINFP/TRIAP1/AURKA/BRSK1/SOX4/BRCC3/WDR76/PRMT1/E2F8	67
BP	GO:0072511	divalent inorganic cation transport	207/7096	489/18670	0.02619	0.1105	0.08238	SLC8A1/SLC40A1/HTR2B/VDR/PKD2L1/FYN/KCNN4/PTPN6/LILRB2/ATP2B4/TMEM37/LYN/SLC11A1/MCOLN1/TPCN1/DIAPH1/TMBIM6/PTGS2/LILRA5/SLC25A25/ORAI2/LILRA2/CXCL9/YME1L1/CXCL11/PTPRC/P2RX7/SLC9A1/CXCL10/PKD2/LILRB1/CXCL12/CACNA2D3/TGFB1/KCNE3/MRS2/ITPR1/WFS1/ISCU/PTK2B/MYO5A/PANX1/NIPA2/CORO1A/P2RY6/CATSPER1/MCU/CNNM2/AHNAK/RYR1/SARAF/CDK5/PDE4B/ABL1/SLC39A10/STIM2/NIPAL4/GSTO1/HOMER3/CCL5/PLCG2/PML/CYSLTR1/ATP2C1/P2RY12/CNNM4/SLC39A8/DMD/TRPM4/ATP7B/AFG3L2/TRPM2/SLC39A13/HOMER1/SLC39A1/ORAI3/TMC2/LCK/PDGFB/G6PD/IL16/SPINK1/CCR5/SLC39A7/SUMO1/PSEN2/SRI/MIR34A/RASA3/NIPA1/P2RX1/ZDHHC13/NMUR2/ANXA6/BCL2/GNAI2/CCL8/BAX/INPP5K/ATP1B1/MS4A1/CHRNA10/PRKACA/LPAR3/CYBA/MICU1/MCOLN2/CAMK2A/ZMPSTE24/SLC30A6/SLC39A12/F2R/GRIN2C/DNM1L/VDAC1/CHRNA4/SLC41A1/SLC35G1/MYLK/CAMK2D/PLCB1/CEMIP/TUSC3/SLC41A2/ORAI1/CAV3/ATP2A2/ANXA2P2/LETM1/SLC8A2/STAC2/PSEN1/FMR1/GPR35/CHRNB2/PARL/YWHAE/TCN1/CYP27B1/NIPAL3/EPB41/CASQ1/PLA2G6/CD84/SLC24A4/CAPN3/CASQ2/CACNG6/HRC/IFNG/PKD1L2/MICU3/EFHB/ATP7A/SLC30A2/CLCA1/BDKRB1/OPRD1/CD4/EHD3/TMEM38B/MMGT1/LACRT/IL1RAPL1/PIK3CG/PMPCB/CACNB3/REM2/CD33/OPRL1/ANXA2/LIME1/RHOA/TRPV4/SNCA/CX3CL1/P2RX2/SLC24A2/CCL19/SLN/TRPC4AP/SLC30A10/BAK1/CHERP/GCG/CCL4/SLC30A9/TMC1/KCNE2/ATP1A2/CCR7/SLC8A3/MCOLN3/CACNA2D4/FAM155A/GJA1/CACNA1H/CACNA1F/ADCYAP1R1/TRPV3/BIN1/TRPV2/NTSR1/PACSIN3/MICU2/CAMK2B/P2RX5	207
BP	GO:0007091	metaphase/anaphase transition of mitotic cell cycle	28/7096	54/18670	0.02641	0.1113	0.083	DUSP1/MAD2L2/DYNC1LI1/SPDL1/CENPE/KLHL22/CDK5RAP2/NSMCE2/CDC23/ESPL1/ZNF207/LCMT1/ATM/ANAPC5/BUB3/NDC80/GEN1/ZW10/CDC26/RIOK2/DLGAP5/ANAPC4/CDC27/CDC20/PCID2/RB1/ANAPC11/IK	28
BP	GO:0042303	molting cycle	53/7096	112/18670	0.02728	0.1148	0.08556	RBPJ/WNT5A/PTGS2/LGR4/LDB1/TNF/RELA/MYO5A/SOX21/FUZ/PTCH2/INTU/TRADD/NSUN2/GORAB/SAV1/ACVR1B/EDA/HPSE/HDAC2/EDAR/BCL2/KRTAP4-5/INHBA/PDGFA/ZMPSTE24/EGFR/DNASE1L2/CLOCK/LGR5/ERCC2/SNAI1/TMEM79/ARNTL/ATP7A/KRT27/TERT/KRT14/CDH3/KRTAP4-8/FOXN1/KRT84/WNT10A/TRPC4AP/LRP4/ZDHHC21/WNT10B/APCDD1/SMO/LRIG1/TRPV3/NOM1/CD109	53
BP	GO:0042633	hair cycle	53/7096	112/18670	0.02728	0.1148	0.08556	RBPJ/WNT5A/PTGS2/LGR4/LDB1/TNF/RELA/MYO5A/SOX21/FUZ/PTCH2/INTU/TRADD/NSUN2/GORAB/SAV1/ACVR1B/EDA/HPSE/HDAC2/EDAR/BCL2/KRTAP4-5/INHBA/PDGFA/ZMPSTE24/EGFR/DNASE1L2/CLOCK/LGR5/ERCC2/SNAI1/TMEM79/ARNTL/ATP7A/KRT27/TERT/KRT14/CDH3/KRTAP4-8/FOXN1/KRT84/WNT10A/TRPC4AP/LRP4/ZDHHC21/WNT10B/APCDD1/SMO/LRIG1/TRPV3/NOM1/CD109	53
BP	GO:0050868	negative regulation of T cell activation	53/7096	112/18670	0.02728	0.1148	0.08556	PTPN6/LILRB2/ANXA1/IRF1/ARG2/GPNMB/PTPN2/TNFRSF14/BCL6/SMAD7/FGL2/IL4R/CEBPB/CBFB/HFE/CD74/TNFRSF21/LILRB1/DUSP3/TGFB1/SOCS5/IL20RB/PTPN22/ZBTB7B/SOCS6/DTX1/CASP3/IDO1/NFKBID/HMGB1/HLA-G/CTLA4/GLMN/TIGIT/VSIG4/SCGB1A1/PDCD1LG2/NRARP/BMP4/LAG3/CD300A/CD274/LGALS9/LAX1/BTN2A2/HLX/TNFSF4/PAG1/SOCS1/HAVCR2/CD80/TBX21/TWSG1	53
BP	GO:0033006	regulation of mast cell activation involved in immune response	18/7096	32/18670	0.02741	0.1149	0.08569	RAC2/LYN/IL4R/HMOX1/C12orf4/STXBP1/STXBP2/FGR/ADORA2B/UNC13D/CD300A/LGALS9/FER/RABGEF1/IL13RA2/CD84/SNX4/FOXF1	18
BP	GO:0046039	GTP metabolic process	18/7096	32/18670	0.02741	0.1149	0.08569	GNAI3/RAN/AK3/NFS1/RAB23/MBIP/IMPDH1/MOCS2/LRRK2/NME3/NME4/GTPBP1/RHOQ/NME1/MOCS3/RHOA/AMPD3/GIMAP7	18
BP	GO:0046685	response to arsenic-containing substance	18/7096	32/18670	0.02741	0.1149	0.08569	CDKN1A/HMOX1/ATF4/ALAD/ZFAND2A/MAPK13/RBM4/HNRNPA1/GCLC/CPOX/GSTO1/DDX3X/MKNK2/RNF4/VCP/SRRT/DAXX/CPEB2	18
BP	GO:1901661	quinone metabolic process	18/7096	32/18670	0.02741	0.1149	0.08569	CBR4/AKR1B1/AKR1C3/HMGCR/AKR7A2/COQ7/COQ5/AKR1A1/AKR1C1/PDSS1/COQ3/CBR3/COQ10B/COQ9/COQ6/AKR1B10/COQ10A/COQ4	18
BP	GO:2000778	positive regulation of interleukin-6 secretion	18/7096	32/18670	0.02741	0.1149	0.08569	LILRA5/MBP/LILRA2/TNF/IL1RAP/HYAL2/DDX58/IL1B/AIF1/DHX9/HMGB1/MAVS/IFIH1/LGALS9/F2R/TLR8/TRPV4/IL17RC	18
BP	GO:0016575	histone deacetylation	38/7096	77/18670	0.02756	0.1155	0.0861	PINK1/SKI/BCL6/PER2/MORF4L2/TGFB1/SIN3A/MTA3/MSL3/ZBTB7B/VEGFA/SIRT7/HDAC11/MIER1/SMARCAD1/SIRT1/SFPQ/SIN3B/SUDS3/LRRK2/BRMS1L/HDAC10/HDAC2/AKAP8/HDAC7/MAPK8/NACC2/PRKD2/HDAC4/CAMK2D/ELK4/JDP2/TBL1X/HDAC5/TADA3/MTA2/ATXN3L/BRMS1	38
BP	GO:0015748	organophosphate ester transport	50/7096	105/18670	0.02763	0.1157	0.08626	KCNN4/ATP8B2/ATP8A1/SLC25A19/SLC37A2/NPC2/SLC25A25/SLC33A1/PITPNA/APOC1/SCARB1/SLC37A4/P2RX7/SCP2/CETP/APOE/PRELID1/STARD10/PITPNM1/PRKCD/ATP11B/ATP10A/ABCA1/LDLR/C2CD2L/ATP8B1/STARD7/SLC25A5/APOA5/MFSD2A/PLEKHA8/ABCG1/OSBPL2/ABCB4/CPTP/ABCA7/SLC25A33/PRELID2/PLEKHA3/APOA1/SLC25A24/TMEM30A/TRIAP1/SLC25A32/ABCD1/GJA1/GLTP/G6PC/PLEKHA8P1/ATP10B	50
BP	GO:0000959	mitochondrial RNA metabolic process	23/7096	43/18670	0.02785	0.1161	0.08656	MTERF1/TRMT5/FASTKD1/MTERF2/TRMT61B/CHCHD10/PUS1/HSD17B10/TEFM/TBRG4/SLC25A33/PRKAA1/SUPV3L1/YARS2/DARS2/POLRMT/MTO1/PNPT1/TRMT10C/AARS2/FOXO3/WARS2/FASTKD5	23
BP	GO:0006692	prostanoid metabolic process	23/7096	43/18670	0.02785	0.1161	0.08656	ANXA1/PTGS2/MIF/PTGR1/CD74/AKR1C3/PLAA/ZADH2/PTGR2/HPGD/CYP2S1/IL1B/ACOX1/CES2/GSTA1/SIRT1/PNPLA8/PTGES3/HPGDS/FABP5/ATP6V1B1/ABHD16A/PTGS1	23
BP	GO:0006693	prostaglandin metabolic process	23/7096	43/18670	0.02785	0.1161	0.08656	ANXA1/PTGS2/MIF/PTGR1/CD74/AKR1C3/PLAA/ZADH2/PTGR2/HPGD/CYP2S1/IL1B/ACOX1/CES2/GSTA1/SIRT1/PNPLA8/PTGES3/HPGDS/FABP5/ATP6V1B1/ABHD16A/PTGS1	23
BP	GO:0010824	regulation of centrosome duplication	23/7096	43/18670	0.02785	0.1161	0.08656	NUP62/KAT2B/CHMP4B/TRIM37/CEP131/PLK2/NPM1/CDK5RAP2/CEP76/SPICE1/CHMP2A/GEN1/CHMP1A/VPS4B/BRCA1/CHORDC1/KAT2A/PKHD1/CEP120/CHMP1B/ROCK2/ALMS1/CCNF	23
BP	GO:0045746	negative regulation of Notch signaling pathway	23/7096	43/18670	0.02785	0.1161	0.08656	BCL6/RITA1/LFNG/FBXW7/NFKBIA/NOTCH3/ZBTB7A/ARRB1/METTL3/HEY1/DLK1/BMP7/HIF1AN/GDPD5/NRARP/MMP14/DLK2/EGFR/WWP2/SLC35C1/HEY2/NOTCH4/EGFL7	23
BP	GO:0045773	positive regulation of axon extension	23/7096	43/18670	0.02785	0.1161	0.08656	FN1/RAB11A/CXCL12/TWF2/PAK1/MEGF8/SRF/VEGFA/TNFRSF12A/PAFAH1B1/GDI1/LRP1/CYFIP1/NRP1/DISC1/L1CAM/NDEL1/SEMA5A/MAP3K13/RUFY3/MACF1/TRPV2/BMPR2	23
BP	GO:0050850	positive regulation of calcium-mediated signaling	23/7096	43/18670	0.02785	0.1161	0.08656	IGF1/CAMTA1/CIB1/TNF/SLC9A1/PKD2/P2RY6/NRG1/GSTO1/HINT1/TRAT1/LMCD1/ADA/TREM2/CHP2/CD4/LACRT/P2RX2/CHERP/CCL4/CD3E/ERBB3/P2RX5	23
BP	GO:0046889	positive regulation of lipid biosynthetic process	41/7096	84/18670	0.02787	0.1161	0.08657	FPR2/HTR2B/SLC27A1/ANXA1/POR/STARD4/CAPN2/PTGS2/SIRT4/ABHD6/RDH10/SLC45A3/SCARB1/TNF/CD74/ELOVL5/APOE/LPGAT1/NR1H2/PRKCD/IL1B/LDLR/CREB1/CREBL2/DGAT2/FABP3/PPARGC1A/FGF1/RAB38/APOA5/ABCG1/NR1H3/PRKAA1/APOA1/PLA2G6/IFNG/ZBTB20/MTOR/ABCD1/SMPD2/NR1H4	41
BP	GO:0046513	ceramide biosynthetic process	31/7096	61/18670	0.02793	0.1163	0.08667	ASAH1/SGMS2/CERS2/P2RX7/DEGS1/TNF/CLN8/PRKCD/B4GALT6/CERS5/SPTLC2/SAMD8/CERS4/ORMDL2/SPHK1/P2RX1/ORMDL3/SGMS1/B4GALNT1/B4GALT5/UGCG/ST8SIA4/AGK/PRKAA1/PLA2G6/ST6GALNAC3/SMPD1/ST6GALNAC6/SMPD2/ST3GAL5/DEGS2	31
BP	GO:0045639	positive regulation of myeloid cell differentiation	44/7096	91/18670	0.02796	0.1163	0.08667	FOS/ATP6AP1/STAT3/KLF10/KITLG/STAT1/TNF/CD74/TESC/HCLS1/FAM210B/TGFB1/HIF1A/ROR2/TRAF6/CASP8/ISG15/CREB1/TYROBP/ACVR1B/TAL1/ETS1/TMEM64/HMGB2/ID2/INHBA/EVI2B/RAB7B/ARNT/FADD/SCIN/DCSTAMP/TREM2/IFNG/CD4/RB1/IL12B/SLC9B2/TRIM58/PRMT1/PRKCA/IL23A/FOXO3/THPO	44
BP	GO:1901992	positive regulation of mitotic cell cycle phase transition	44/7096	91/18670	0.02796	0.1163	0.08667	ANXA1/CCND3/RAB11A/MEPCE/RGCC/LSM11/CCND2/TMOD3/CDK4/TGFB1/RDX/SIN3A/MTA3/DBF4B/RAD51B/AIF1/NSMCE2/CCND1/ESPL1/DDX3X/ANAPC5/KMT2E/UBE2E2/CCNE1/ANKRD17/CDC25A/VPS4B/UBE2C/DTL/PLCB1/EGFR/ADAM17/RCC2/MDM2/DLGAP5/EIF4G1/ANAPC4/MTBP/CUL4B/RB1/TERT/ANAPC11/APP/WNT10B	44
BP	GO:0016447	somatic recombination of immunoglobulin gene segments	27/7096	52/18670	0.02836	0.1178	0.08785	IL27RA/MAD2L2/STAT6/BCL6/CD40/PTPRC/BATF/TGFB1/UNG/SWAP70/XRCC4/MLH1/PARP3/ERCC1/CLCF1/CCR6/LIG4/TFRC/TNFSF4/EXO1/EXOSC3/POLB/TBX21/APLF/EXOSC6/PAXIP1/ATAD5	27
BP	GO:0043409	negative regulation of MAPK cascade	83/7096	184/18670	0.02841	0.118	0.08798	KLF4/EZR/PTPN6/DUSP1/DUSP6/LYN/PINK1/PPP2CA/DUSP5/CSK/GBP1/PTPN2/NUP62/DUSP10/RGS2/UCHL1/MYC/DUSP7/NLRP12/RNF149/GSTP1/PTPRC/P2RX7/IRAK3/EPHB2/PEBP1/APOE/HMGCR/DUSP3/NDRG2/TAOK3/ARRB1/DUSP18/RANBP9/PRKCD/HYAL2/MBIP/DUSP2/TLR4/PTPN22/IGF1R/ABL1/PAFAH1B1/IL1B/PAQR3/BMP7/DUSP19/CYLD/FLCN/DUSP14/RGS3/DUSP4/NCOR1/ASH1L/BMP4/TNIP1/INPP5K/RGS14/CHRNA10/ZMYND11/CD300A/LAX1/BTN2A2/AMBP/SPRY1/SPRED1/CAV3/SPRY2/PPEF2/IGBP1/HIPK3/DNAJA1/PIN1/SMPD1/MEN1/PRDM15/GPS1/DAG1/ITGB1BP1/PDCD4/AIDA/WNK2/PTPRJ	83
BP	GO:0071326	cellular response to monosaccharide stimulus	63/7096	136/18670	0.02862	0.1188	0.08855	TRA2B/GCLM/ENY2/HMGCR/LRP5/PPP3CB/SIN3A/AACS/UNC13B/FIS1/ARRB1/HIF1A/PIM3/PCK2/LEP/SRF/IGF1R/GCLC/AGER/C2CD2L/RAP1A/MPC2/LRP1/RAF1/TRPM4/RAC1/IRS2/ZNF236/PPARGC1A/KLF7/SRI/OXCT1/POLG/GPR27/NME1/PRKACA/LGALS1/PDX1/CYBA/PTPRN2/HMGN3/CMA1/PRKAA1/BAD/PLA2G6/KIF5B/MEN1/WDR35/ZBTB20/NDUFAF2/MAP4K4/ERN1/SLC9B2/SOX4/SIDT2/GCG/ENDOG/NR1H4/STXBP4/FOXO3/GHRL/MIR146A/PHPT1	63
BP	GO:0010508	positive regulation of autophagy	55/7096	117/18670	0.02868	0.119	0.08869	PINK1/TSC1/C9orf72/TPCN1/GNAI3/DHRSX/HMOX1/TRIM13/GSK3B/TICAM1/SH3BP4/CDC37/HIF1A/TRIM22/TFEB/IKBKG/TP53INP2/SPTLC2/PLK2/RAB3GAP1/DAPK1/HMGB1/SIRT1/GPSM1/LRRK2/FLCN/BCL2L11/PLK3/KAT5/VPS13D/EPM2A/TRIM21/MEFV/ADRB2/ULK1/MUL1/MID2/SESN1/PRKAA1/SH3GLB1/SMCR8/NPRL2/BAD/IFNG/TRIM65/CLEC16A/LACRT/OPTN/MTDH/EIF2AK4/PIM2/HMGB4/SESN2/FOXO3/PIK3CB	55
BP	GO:0032874	positive regulation of stress-activated MAPK cascade	78/7096	172/18670	0.02871	0.119	0.08871	NOD2/WNT5A/ZNF622/SH3RF1/DVL2/TNF/ERCC6/ZEB2/MAP3K4/HMGCR/SLAMF1/TAOK3/GADD45B/PAK1/MAP4K5/PTK2B/LEP/ROR2/TRAF6/NCF1/TLR4/TPD52L1/BMP2/VEGFA/HRAS/IL1B/SEMA4C/AGER/MAP3K12/RASGRP1/SDCBP/MDFIC/HMGB1/TNFRSF11A/IL1RN/MFHAS1/DUSP19/MAP4K2/RELL2/SPHK1/EDAR/MAP3K6/MAP4K1/MLKL/MAP3K11/SH3RF3/FZD5/BIRC7/MAP3K5/PLCB1/EIF2AK2/MUL1/TRAF2/FZD4/MAP2K4/MAP3K13/ANKRD6/TLR3/FZD7/TRPV4/APP/ERN1/PDCD10/CCL19/TIRAP/TRAF4/WNT7A/CCR7/PRMT1/IL26/DAXX/SERPINF2/TLR6/FZD10/NRK/SASH1/IL37/MAP3K9	78
BP	GO:0008202	steroid metabolic process	143/7096	331/18670	0.02889	0.1197	0.08923	VDR/ASAH1/HSD17B14/POR/STARD4/CYP27A1/SOD1/ATP1A1/SRD5A1/AKR1B1/NFYC/GPAM/NPC2/SPP1/PPARD/PLEKHA1/ACAA1/LIPA/DDX20/PANK2/CYB5R1/OSBPL9/YWHAH/LGMN/FAXDC2/APOC1/SCARB1/SQLE/EGR1/SOAT1/TNF/SCP2/AKR1C3/CETP/NFKB1/RAN/IGFBP7/APOE/HMGCR/LIMA1/DHRS9/HDLBP/CLN8/OSBPL1A/HMGCS1/CYP1B1/SGPL1/SCD/LEP/ERLIN1/RDH16/CNBP/CEBPA/BMP2/AKR1C1/CAT/ACLY/ABCA1/IL1B/LAMTOR1/HSD11B1/LDLR/STARD3NL/LMF1/ERLIN2/FDPS/SLC27A2/HSD17B4/ACACB/ATP8B1/ACOX2/APOBR/SIRT1/DGAT2/G6PD/PPARGC1A/FGF1/ARV1/APOL1/GNB3/TM7SF2/APOA5/WWOX/MSMO1/IDI1/PRKAG2/BMP5/CYP2D6/LCAT/RXRA/CYP1A2/SCAP/CYP26B1/TIPARP/ABCG1/APOL2/SC5D/ACBD3/CH25H/EBPL/CLN6/OSBPL2/RDH5/ABCB11/SREBF2/ACADVL/CYB5R3/STUB1/FDX1/NFE2L1/STS/SERPINA12/INSIG1/HINT2/ACAA2/SRD5A3/PRKAA1/HSD17B3/APOA1/CYP27B1/RORA/SNAI1/IFNG/TFCP2L1/SMPD1/SULT1B1/CYP26A1/SDR42E1/MBTPS2/APP/ELOVL6/MBTPS1/KPNB1/CYP2A6/CYP46A1/FGF23/CACNA1H/CYP2C8/NR1H4/G6PC/HSD17B12/SNX17/ACOT8	143
BP	GO:0032607	interferon-alpha production	17/7096	30/18670	0.0291	0.1201	0.08954	IRF7/STAT1/NMI/TLR4/DDX58/DHX9/MMP12/HMGB1/MAVS/AZI2/IFIH1/TLR8/HAVCR2/TLR3/CHUK/HMGB4/NLRC3	17
BP	GO:0045948	positive regulation of translational initiation	17/7096	30/18670	0.0291	0.1201	0.08954	PPP1R15A/TNF/KHDRBS1/YTHDF3/METTL3/EIF2B5/HABP4/NCK1/CCL5/DDX3X/RXRA/POLR2D/IMPACT/RPS6KB2/EIF2AK4/MTOR/BOLL	17
BP	GO:0046320	regulation of fatty acid oxidation	17/7096	30/18670	0.0291	0.1201	0.08954	PDK4/APPL2/SIRT4/ACACB/DGAT2/FABP3/IRS2/PPARGC1A/MLYCD/PRKAG2/TYSND1/CPT1A/ACADVL/PPARA/NR4A3/MTOR/ABCD1	17
BP	GO:0050869	negative regulation of B cell activation	17/7096	30/18670	0.0291	0.1201	0.08954	LYN/MNDA/BCL6/TNFAIP3/BANK1/TNFRSF21/CASP3/TYROBP/CTLA4/ATM/PARP3/ID2/INHBA/CD300A/TNFRSF13B/INHA/SLA2	17
BP	GO:0090200	positive regulation of release of cytochrome c from mitochondria	17/7096	30/18670	0.0291	0.1201	0.08954	BMF/PINK1/PMAIP1/TNFSF10/CHCHD10/PLAUR/PDCD5/BCL2L11/MMP9/BAX/MLLT11/DNM1L/BAD/PLA2G6/MOAP1/WDR35/BAK1	17
BP	GO:1904292	regulation of ERAD pathway	17/7096	30/18670	0.0291	0.1201	0.08954	BCAP31/EDEM1/SGTA/UBE2J1/UBE2G2/EDEM2/RNFT1/UBQLN2/DERL2/NFE2L2/ATXN3/YOD1/UBXN1/RNF185/USP19/ERLEC1/OS9	17
BP	GO:0046173	polyol biosynthetic process	37/7096	75/18670	0.02958	0.1219	0.09089	ASAH1/GCH1/CYP27A1/AKR1B1/IMPAD1/PCBD1/PTAFR/IP6K1/PTK2B/PCK2/LEP/P2RY6/SPTLC2/PLCG2/PPIP5K2/QDPR/PTS/SPR/SPHK1/PLCL1/IMPA2/PLEK/PLCD1/PLCB1/DHFR/IPPK/PLCD4/ACER3/CYP27B1/PLCL2/PCBD2/SNCA/CD244/ADCYAP1R1/P2RY1/NTSR1/IMPA1	37
BP	GO:1903201	regulation of oxidative stress-induced cell death	37/7096	75/18670	0.02958	0.1219	0.09089	FYN/ATG7/PINK1/TSC1/SOD1/FBXW7/PSAP/SLC7A11/ATF4/HGF/HIF1A/HSPB1/MAPK7/MCL1/HTRA2/TLR4/NCOA7/SIRT1/SFPQ/LRRK2/MIR34A/VNN1/MMP3/FZD1/NFE2L2/TXN/WNT1/NR4A3/LANCL1/GPX1/PDE8A/BAG5/MET/ENDOG/TLR6/FOXO3/OXR1	37
BP	GO:0034248	regulation of cellular amide metabolic process	204/7096	483/18670	0.02979	0.1226	0.0914	IGF1/EIF1/PDK4/PINK1/CTSA/ZFP36/TSC1/STAT3/VIM/DPH3/PPP1R15A/GAPDH/ENC1/TOB1/ALKBH1/RPS6KA3/BANK1/RGS2/PER2/RNF139/AGO2/SEPSECS/TNF/SLC7A11/EIF1B/KHDRBS1/YTHDF3/MOV10/HNRNPR/METTL14/GIGYF2/APOE/SECISBP2/BTG2/TRNAU1AP/PGAM1/ATF4/PDK2/PAIP1/EIF6/CDK4/UQCC1/SARNP/PTAFR/HSPB1/PTK2B/PRKCD/EIF4E3/METTL3/MTIF2/SECISBP2L/CNBP/RBM4/SAMD4B/RBM4B/PIWIL4/EIF2B5/HABP4/NCK1/CASP3/EIF4B/NPM1/DPH5/PURA/GSTZ1/TMED10/LARP4/RBM8A/SAMD8/GUF1/UQCC2/CCL5/DHX9/DAPK1/ZC3H12D/CLU/LSM14B/ACO1/PPP1R15B/EIF4E2/EIF4H/EIF2S1/EIF4EBP2/CAPRIN1/IL6/EIF4G2/CYFIP1/DNAJC1/ATXN2/NOLC1/NAT10/LSM14A/PUM2/DDX3X/ILF3/SERP1/RBM3/RPS9/MAPKAPK5/ORMDL2/DPH2/SPHK1/SHMT2/KBTBD8/PLK3/FTO/RXRA/USP16/ORMDL3/TARBP2/XRN1/EIF4G3/ABCG1/CPEB1/PRR16/AGO1/ETF1/DDX1/ITGA2/PDK1/EIF3B/TNRC6B/TYMS/EIF5/GRB7/ZCCHC4/TNRC6A/HNRNPD/CPEB3/YBX3/IREB2/POLR2D/CALR/EEF1A2/ABCA7/NFE2L2/IMPACT/UNK/COA3/SHMT1/PPP1CA/PDP2/IFNGR1/EIF2AK2/LARP4B/C1QBP/DHFR/CNOT7/EIF5A/NGRN/PRKAA1/FMR1/MAPK1/KLHL25/NOTCH4/EIF2AK1/ZFP36L2/EIF4G1/PLA2G6/EIF2B1/RPUSD3/EIF2A/MKNK2/EIF4E/IFNG/RPS6KB2/PDP1/PIN1/JMJD4/CNOT10/MTRF1/EIF2AK4/MTOR/RHOA/APP/SNCA/SAMD4A/ZNF706/SOX4/GSAP/TRMT10C/MPV17L2/PUS7/SMPD2/PDPR/DIO2/EIF2B2/PICALM/ROCK2/DNAJC24/EIF4ENIF1/SYNCRIP/BOLL/NR1H4/SESN2/BIN1/PA2G4/MIR205/PAIP2B/CPEB2/FOXO3/PLEKHN1/NEMF/UPF1	204
BP	GO:0070838	divalent metal ion transport	204/7096	483/18670	0.02979	0.1226	0.0914	SLC8A1/SLC40A1/HTR2B/VDR/PKD2L1/FYN/KCNN4/PTPN6/LILRB2/ATP2B4/TMEM37/LYN/SLC11A1/MCOLN1/TPCN1/DIAPH1/TMBIM6/PTGS2/LILRA5/SLC25A25/ORAI2/LILRA2/CXCL9/YME1L1/CXCL11/PTPRC/P2RX7/SLC9A1/CXCL10/PKD2/LILRB1/CXCL12/CACNA2D3/TGFB1/KCNE3/MRS2/ITPR1/WFS1/ISCU/PTK2B/MYO5A/PANX1/NIPA2/CORO1A/P2RY6/CATSPER1/MCU/CNNM2/AHNAK/RYR1/SARAF/CDK5/PDE4B/ABL1/SLC39A10/STIM2/NIPAL4/GSTO1/HOMER3/CCL5/PLCG2/PML/CYSLTR1/ATP2C1/P2RY12/CNNM4/SLC39A8/DMD/TRPM4/AFG3L2/TRPM2/SLC39A13/HOMER1/SLC39A1/ORAI3/TMC2/LCK/PDGFB/G6PD/IL16/SPINK1/CCR5/SLC39A7/SUMO1/PSEN2/SRI/MIR34A/RASA3/NIPA1/P2RX1/ZDHHC13/NMUR2/ANXA6/BCL2/GNAI2/CCL8/BAX/INPP5K/ATP1B1/MS4A1/CHRNA10/PRKACA/LPAR3/CYBA/MICU1/MCOLN2/CAMK2A/ZMPSTE24/SLC30A6/SLC39A12/F2R/GRIN2C/DNM1L/VDAC1/CHRNA4/SLC41A1/SLC35G1/MYLK/CAMK2D/PLCB1/CEMIP/TUSC3/SLC41A2/ORAI1/CAV3/ATP2A2/ANXA2P2/LETM1/SLC8A2/STAC2/PSEN1/FMR1/GPR35/CHRNB2/PARL/YWHAE/CYP27B1/NIPAL3/EPB41/CASQ1/PLA2G6/CD84/SLC24A4/CAPN3/CASQ2/CACNG6/HRC/IFNG/PKD1L2/MICU3/EFHB/SLC30A2/CLCA1/BDKRB1/OPRD1/CD4/EHD3/TMEM38B/MMGT1/LACRT/IL1RAPL1/PIK3CG/PMPCB/CACNB3/REM2/CD33/OPRL1/ANXA2/LIME1/RHOA/TRPV4/SNCA/CX3CL1/P2RX2/SLC24A2/CCL19/SLN/TRPC4AP/SLC30A10/BAK1/CHERP/GCG/CCL4/SLC30A9/TMC1/KCNE2/ATP1A2/CCR7/SLC8A3/MCOLN3/CACNA2D4/FAM155A/GJA1/CACNA1H/CACNA1F/ADCYAP1R1/TRPV3/BIN1/TRPV2/NTSR1/PACSIN3/MICU2/CAMK2B/P2RX5	204
BP	GO:0044091	membrane biogenesis	22/7096	41/18670	0.02983	0.1226	0.09143	S100A10/PEX11A/PACSIN2/FLOT1/PSAP/EPHB2/PEX16/SERINC1/SPTBN1/FLOT2/EMP2/PEX3/UGCG/CAV3/ANXA2P2/DMKN/IL1RAPL1/ANXA2/CLIP3/LRP4/NLGN2/RFTN1	22
BP	GO:0150077	regulation of neuroinflammatory response	22/7096	41/18670	0.02983	0.1226	0.09143	IGF1/GRN/PTGS2/CTSC/PTPRC/TNF/NUPR1/MIR142/IL1B/LDLR/TTBK1/IL6/LRRK2/CD200R1/CST7/ATM/SPHK1/MMP9/MMP3/IL18/TREM2/CX3CL1	22
BP	GO:0097581	lamellipodium organization	40/7096	82/18670	0.0299	0.1228	0.09158	RAC2/SNX1/ENPP2/SPATA13/S1PR1/CD44/VCL/PTPRO/TWF2/NUP85/PARVB/PLEKHO1/NCK1/ARHGEF6/P2RY12/RAC1/ARPIN/CCDC88A/CYFIP1/CORO1B/SRGAP2/ABLIM3/DNM2/HDAC4/KANK1/FER/DMTN/CORO1C/BIN3/SLIT2/FSCN1/WNT1/ATP7A/HRG/ARPC2/MTOR/ARHGEF4/WAS/NCKAP1/ABLIM1	40
BP	GO:0072413	signal transduction involved in mitotic cell cycle checkpoint	30/7096	59/18670	0.03001	0.123	0.09173	CDKN1A/RGCC/BTG2/PLK2/SFN/PML/ATM/TNKS1BP1/MUC1/PLK3/PCNA/BAX/CRADD/CASP2/CDKN1B/CNOT4/PLAGL1/ARID3A/E2F4/CNOT7/GML/MDM2/RBL2/CNOT10/CARM1/TRIAP1/AURKA/SOX4/PRMT1/E2F8	30
BP	GO:1902402	signal transduction involved in mitotic DNA damage checkpoint	30/7096	59/18670	0.03001	0.123	0.09173	CDKN1A/RGCC/BTG2/PLK2/SFN/PML/ATM/TNKS1BP1/MUC1/PLK3/PCNA/BAX/CRADD/CASP2/CDKN1B/CNOT4/PLAGL1/ARID3A/E2F4/CNOT7/GML/MDM2/RBL2/CNOT10/CARM1/TRIAP1/AURKA/SOX4/PRMT1/E2F8	30
BP	GO:1902403	signal transduction involved in mitotic DNA integrity checkpoint	30/7096	59/18670	0.03001	0.123	0.09173	CDKN1A/RGCC/BTG2/PLK2/SFN/PML/ATM/TNKS1BP1/MUC1/PLK3/PCNA/BAX/CRADD/CASP2/CDKN1B/CNOT4/PLAGL1/ARID3A/E2F4/CNOT7/GML/MDM2/RBL2/CNOT10/CARM1/TRIAP1/AURKA/SOX4/PRMT1/E2F8	30
BP	GO:0045666	positive regulation of neuron differentiation	159/7096	371/18670	0.03003	0.1231	0.09174	S100A9/FN1/FYN/TRIM32/DPYSL3/SKIL/GRN/LYN/WNT5A/CYB5D2/TIMP2/BCL6/RAB11A/MMD/CAMK1D/MAP2K1/RGS2/ALK/DVL2/EZH2/ARHGDIA/GPRC5B/APOE/ZEB2/ACTR2/PLAA/CXCL12/PLXNB2/LRP8/TWF2/SIN3A/ARSB/HGF/PAK1/RAPGEF2/MEGF8/SS18L2/PTK2B/PLXNC1/CSNK1D/SRF/SCN1B/BAIAP2/ITSN1/TCF12/BMP2/HSPA5/NCK1/FIG4/VEGFA/TNFRSF12A/PAFAH1B1/GDI1/GRIP1/CREB3L2/FBXO38/PTK6/ARHGEF2/RAP1A/SEMA4D/ANKRD27/LRP1/NPTN/BMP7/TMEM106B/CAPRIN1/ETV5/KALRN/CYFIP1/CRTC1/ARF1/CSNK1E/SETX/GDPD5/PLXNA1/BMP5/NRP1/DISC1/PLXND1/BCL2/BMP4/AVIL/L1CAM/MARK2/KCTD11/NME1/LPAR3/IST1/NDEL1/DAB1/MOB2/SHANK1/CPEB3/SEMA5A/ITGA3/TGIF2/LPAR1/BHLHB9/DNM1L/AP2A1/FZD1/NFE2L2/IMPACT/CNTF/MUL1/AMIGO1/ABL2/SS18L1/FZD4/ITSN2/SLIT2/LRRC7/DVL1/CPNE1/PSEN1/FMR1/GPC2/SHOX2/EIF4G1/KATNB1/RASAL1/MAP3K13/RUFY3/PLXNA3/SYT1/RET/TRAK1/CPNE9/TMEM30A/IL1RAPL1/PPP2R5B/DUOXA1/PLXNA2/SYT2/PRPF19/SYT4/RELN/MTOR/CHODL/RHOA/HMG20B/C21orf91/CX3CL1/PARP6/CRABP2/RIMS2/SOCS2/SHANK3/MMD2/MACF1/CNTN1/TRPV2/ZMYND8/NTRK2/MEF2C/CAMK2B/BMPR2/MIR146A/GDF5	159
BP	GO:0032869	cellular response to insulin stimulus	96/7096	216/18670	0.0302	0.1236	0.09216	SH2B2/ATP6V0D2/PDK4/APPL2/SOCS3/TSC1/SRSF5/SRD5A1/ATP6AP1/PTPN2/CCND3/ATP6V1C1/ADIPOR1/STAT1/GSTP1/C2CD5/ATP6V0C/SLC9A1/CISH/GSK3B/GAB1/RAB31/PIK3R3/KAT2B/GKAP1/PKM/RELA/PDK2/SLC2A8/CDK4/PAK1/ENHO/MYO5A/PCK2/LEP/SYAP1/PRKCD/INSR/BAIAP2/TCIRG1/ZBTB7B/IGF1R/NCK1/ATP6V1A/GCLC/IL1B/SIK2/SHC1/PHIP/RAB8A/ATP6V1G3/SIRT1/EIF4EBP2/ATP6V1B2/IRS2/CYFIP1/MYO1C/DENND4C/ATP6V1D/GRB10/GNAI2/ATP6V0E2/INPP5K/GPR21/RHOQ/CPEB1/KANK1/NDEL1/PPAT/GRB2/FOXO4/FER/ATP6V1G2/SERPINA12/RAB8B/SLC25A33/KL/PRKAA1/PID1/SOCS1/ZNF106/OGT/YWHAG/SLA2/PRKCZ/PRKCQ/HDAC5/ATP6V1B1/SMARCC1/APPL1/SOCS2/NUCKS1/NR1H4/STXBP4/CPEB2/FOXO3	96
BP	GO:0072659	protein localization to plasma membrane	114/7096	260/18670	0.0302	0.1236	0.09216	MYADM/S100A10/EZR/MPP5/STX7/PLS1/ARF6/RILPL1/CSK/GBP1/GGA2/ANKRD9/RAB11A/FLNA/FCHO2/CIB1/FLOT1/SQSTM1/F11R/DCHS1/VAMP5/TNF/C2CD5/EPHB2/SYS1/RAPGEF6/TESC/RAB31/ACTB/TGFB1/RDX/STXBP1/GRIPAP1/RAPGEF2/MYO5A/RHOG/TTC7A/GOPC/GORASP2/CDK5/VAMP3/FAM126A/C16orf70/GRIP1/NUMB/CNST/RAP1A/LRP1/BBS2/RAB8A/PREPL/SPTBN1/FLOT2/DENND4C/ATP1B3/EMP2/GOLPH3L/INPP5K/PACS2/ATP1B1/RHOQ/GRASP/TSPAN33/TMEM88/CNPY4/RANGRF/KIF13A/GPR158/NKD2/ARFRP1/ITGA3/MMP14/TSPAN5/CLASP2/DPP6/RAB8B/EGFR/CAV3/ANXA2P2/LRRC7/STAC2/RAB3A/PID1/IFT20/VTI1B/PRAM1/SLC4A1/TREM2/SYTL2/IFNG/PKP2/SKAP1/STX8/KIF5B/EHD3/RAB3B/CACNB3/OPTN/AP2M1/PRKCZ/ANXA2/RAB3D/CLIP3/ITGB1BP1/RER1/FGF13/PICALM/ROCK2/APPL1/RAB26/EFR3A/P2RY1/PTCH1/MACF1	114
BP	GO:0045540	regulation of cholesterol biosynthetic process	26/7096	50/18670	0.03045	0.1245	0.09279	POR/SOD1/NFYC/GPAM/SQLE/RAN/APOE/HMGCR/HMGCS1/SCD/ERLIN1/ERLIN2/FDPS/ACACB/FGF1/TM7SF2/IDI1/SCAP/ABCG1/SC5D/SREBF2/PRKAA1/MBTPS2/ELOVL6/MBTPS1/KPNB1	26
BP	GO:0106118	regulation of sterol biosynthetic process	26/7096	50/18670	0.03045	0.1245	0.09279	POR/SOD1/NFYC/GPAM/SQLE/RAN/APOE/HMGCR/HMGCS1/SCD/ERLIN1/ERLIN2/FDPS/ACACB/FGF1/TM7SF2/IDI1/SCAP/ABCG1/SC5D/SREBF2/PRKAA1/MBTPS2/ELOVL6/MBTPS1/KPNB1	26
BP	GO:0006022	aminoglycan metabolic process	77/7096	170/18670	0.03049	0.1245	0.09279	FUCA1/HS3ST2/HEXB/VCAN/ABCC5/EXTL2/CHSY1/NDST2/HS2ST1/PIM1/B3GNT8/NAGLU/CHP1/IDS/CD44/IL15/IMPAD1/SLC9A1/EXT2/EXT1/NFKB1/HEXA/CHST13/TGFB1/B3GNT2/ARSB/HGF/SGSH/CHST2/HYAL2/B4GALT6/CSGALNACT1/GNS/B3GNT5/IL1B/CSPG4/ST3GAL2/XYLT1/CHST11/SLC35D1/B3GALT6/GLCE/CHST5/IDUA/PDGFB/CTBS/CHST14/XYLT2/GUSB/HPSE/NDST1/CSGALNACT2/HS3ST1/CLN6/SPOCK2/B4GALT5/HYAL3/PGLYRP4/BCAN/AP2A1/HS3ST3B1/CEMIP/GPC2/B3GNT4/ST3GAL1/STAB2/CHST12/GCNT2/B3GAT3/HS3ST6/GPC4/LYVE1/SDC3/B4GALT1/SLC35D2/ITIH3/CHST7	77
BP	GO:0043433	negative regulation of DNA-binding transcription factor activity	77/7096	170/18670	0.03049	0.1245	0.09279	KLF4/MAD2L2/PIM1/BHLHE40/NLRP3/CHP1/FLNA/SMAD7/TNFAIP3/NLRC5/KEAP1/CEBPG/SIK1/G3BP2/NLRP12/EZH2/IRAK3/NFKBIA/HMOX1/NUPR1/PKD2/AIM2/TRIM37/CYP1B1/ARRB1/WFS1/TRAF3/EGLN1/CAT/CACTIN/SP100/CMKLR1/NFKBID/SFRP4/RBCK1/SIRT1/BMP7/CYLD/ZNF431/SUMO1/SRI/MED13/HDAC2/TRIM21/SETD6/HDAC4/ID2/NFKBIE/COMMD1/PEX14/WWP2/USP7/TNFSF4/TAX1BP1/SIGIRR/TCF7L2/DAP/TNFRSF4/HAVCR2/PKHD1/MXI1/RB1/MAP2K5/MEN1/NLRP2/EIF2AK4/ADORA3/RLIM/CHUK/SFRP5/PAXIP1/TONSL/NR1H4/NLRC3/PTCH1/FOXH1/BRMS1	77
BP	GO:0032355	response to estradiol	62/7096	134/18670	0.03051	0.1245	0.0928	CRHBP/NQO1/DUSP1/ANXA1/TXNIP/AIFM1/SRD5A1/STAT3/PTGS2/TFPI/GSTP1/EZH2/FAM210B/TGFB1/STXBP1/NCOA3/HPGD/LEP/MBD1/RUVBL2/MBD3/CAT/CASP3/CASP8/IGFBP2/BMP7/GPX4/CCND1/ARPC1B/PPARGC1A/ETS1/WFDC1/ARNT2/PAM/MYOG/BCL2L11/KAT5/CYP1A2/PCNA/ZNF703/CDKN1B/ITGA2/HNRNPD/CALR/EGFR/DNMT3A/BAD/HTR5A/DDX18/STRN3/CD4/CCNA2/OPRL1/WNT7A/BCL2L2/ENDOG/SOCS2/GJA1/NRIP1/ADCYAP1R1/MBD4/PTCH1	62
BP	GO:0016482	cytosolic transport	72/7096	158/18670	0.03069	0.1251	0.09329	EZR/RAB9A/SNX1/DENND5A/WDR91/FAM160A2/HEATR5A/MAP2K1/WDR81/LAMP1/SYS1/ACTR2/VPS13A/TBC1D5/TMEM87A/RDX/SRSF10/CORO1A/VAMP3/ANKRD27/WIPI1/HOOK2/RAB29/PREPL/GOSR2/LRRK2/GOSR1/CLTCL1/STX5/KIF16B/SNX6/TBC1D17/EMP2/HOOK3/VPS51/RNF126/RAB5A/TMEM87B/STX16/MTMR2/MAP2K2/VPS52/ARL1/VTI1A/CLN5/ARFRP1/RAB7B/YKT6/AP2A1/AP1G1/MAPK1/VPS29/SNX5/MSN/VTI1B/KIF1B/LMTK2/RHOBTB3/EVI5/STX8/KIF5B/TBC1D10C/EHD3/VPS26B/KIF1C/DENND2A/RGP1/SNX16/CCDC91/TBC1D10B/SNX32/TRIM46	72
BP	GO:0032647	regulation of interferon-alpha production	16/7096	28/18670	0.03086	0.1252	0.09333	IRF7/STAT1/NMI/TLR4/DDX58/DHX9/MMP12/HMGB1/MAVS/IFIH1/TLR8/HAVCR2/TLR3/CHUK/HMGB4/NLRC3	16
BP	GO:0032770	positive regulation of monooxygenase activity	16/7096	28/18670	0.03086	0.1252	0.09333	HTR2B/GCH1/POR/SCARB1/TNF/KRAS/APOE/HIF1A/PTK2B/IL1B/FCER2/DHFR/NUS1/IFNG/TERT/CDH3	16
BP	GO:0034698	response to gonadotropin	16/7096	28/18670	0.03086	0.1252	0.09333	GCLM/POR/SRD5A1/HMGCS1/PAX8/GCLC/PPARGC1A/EPHA8/ASNS/INHBA/CTSV/ITGA3/NSMF/CCNA2/FSHR/WT1	16
BP	GO:0045408	regulation of interleukin-6 biosynthetic process	16/7096	28/18670	0.03086	0.1252	0.09333	TLR1/CLEC7A/STAT3/NLRP12/CEBPB/TNF/CD74/PTAFR/TRAF6/IL1B/AGER/TYROBP/APP/TIRAP/TLR6/GHRL	16
BP	GO:0050686	negative regulation of mRNA processing	16/7096	28/18670	0.03086	0.1252	0.09333	BARD1/ZC3H14/RNPS1/RBM42/SRSF10/HNRNPK/HNRNPA2B1/SFSWAP/CDK9/SRSF6/SRSF7/RNF20/C1QBP/SRSF4/CCNT1/SAP18	16
BP	GO:0051123	RNA polymerase II preinitiation complex assembly	16/7096	28/18670	0.03086	0.1252	0.09333	DR1/THRA/TAF11/PSMC4/TAF12/HMGB1/CREB1/PSMC3/CAND1/PSMC6/TAF6L/PSMC5/PSMC2/TBP/WNT10B/TAF7	16
BP	GO:1900543	negative regulation of purine nucleotide metabolic process	16/7096	28/18670	0.03086	0.1252	0.09333	CBFA2T3/FBP1/STAT3/NUPR1/PPARGC1A/FLCN/SLC25A12/MYOG/PFKFB1/HDAC4/DDIT4/PPARA/DNAJC15/PID1/RHOA/SNCA	16
BP	GO:1902003	regulation of amyloid-beta formation	16/7096	28/18670	0.03086	0.1252	0.09333	IGF1/TNF/APOE/CASP3/TMED10/CLU/ABCG1/ABCA7/IFNGR1/IFNG/PIN1/APP/GSAP/PICALM/ROCK2/BIN1	16
BP	GO:0045428	regulation of nitric oxide biosynthetic process	33/7096	66/18670	0.03111	0.126	0.09395	KLF4/KLF2/CX3CR1/ATP2B4/ACP5/CLEC7A/PTGS2/JAK2/TNF/DDAH2/PKD2/TICAM1/CD36/PTK2B/INSR/HBB/PTX3/TLR4/IL1B/AIF1/CLU/RAC1/GLA/DNM2/CD47/AGXT2/IFNG/CD34/HSP90AB1/WDR35/MTOR/ROCK2/TLR6	33
BP	GO:1901607	alpha-amino acid biosynthetic process	33/7096	66/18670	0.03111	0.126	0.09395	ATP2B4/SEPHS2/ADI1/PSPH/MTR/ALDH18A1/APIP/NAGS/MTRR/ENOPH1/GATM/ASNSD1/GLUD1/PLOD1/MTAP/SLC25A12/SHMT2/GLUD2/SERINC3/CTH/ASNS/BHMT/PLOD2/GAMT/GLS/GOT2/AGXT2/SHMT1/AASDHPPT/SRR/CAD/BCAT2/PHGDH	33
BP	GO:0043112	receptor metabolic process	86/7096	192/18670	0.03147	0.1274	0.09499	HTR2B/EZR/SNX1/DNM3/ARAP1/ECE1/FLOT1/ALS2/ACKR3/LGMN/JAK2/TNF/APOE/RAB31/LILRB1/TBC1D5/TGFB1/ARRB1/HIF1A/CD36/LRPAP1/CD63/HNRNPK/NRG1/USP46/VEGFA/CDK5/VAMP3/OPHN1/LAMTOR1/FURIN/NUMB/PLCG2/SDCBP/SFRP4/LRP1/RAB29/CXCR1/ATXN2/ARC/KIF16B/ARF1/DTX3L/HDAC2/DNM1/AP2A2/TRAT1/UBQLN2/DNM2/NEDD4/SCAP/NR1H3/RAB5A/AP2S1/MTMR2/GRB2/INPP5F/AP2A1/GPRASP1/CXCR2/PPARA/CAV3/TFRC/ANXA2P2/PSEN1/FMR1/MKLN1/RNF43/SH3GLB1/LMTK2/IFNG/GRK4/EHD3/OPTN/AP2M1/ANKRD13D/ANXA2/PICK1/SNCA/GSG1L/PICALM/ATAD1/GREM1/SEC24A/CNPY2/APLN	86
BP	GO:0051170	import into nucleus	74/7096	163/18670	0.03156	0.1277	0.0952	CDKN1A/APPL2/TXNIP/LMNA/STAT3/NUP62/IPO13/PTGS2/CHP1/FLNA/DDX20/NUP214/NFKBIA/TNPO1/RAN/HCLS1/TGFB1/RAB23/NUP85/NXT1/CBLB/CD36/LEP/PRKCD/PTTG1IP/HYAL2/KPNA4/HNRNPA1/ZPR1/HTATIP2/SNUPN/SNRPB/GEMIN6/UBR5/MMP12/MDFIC/POM121/PML/GEMIN7/MAVS/LRRK2/NOLC1/SNRPD1/IPO4/BMP4/NUP88/SNRPF/CSE1L/NUP107/NXT2/NUP93/IPO9/PSEN1/IPO7/MAPK1/KPNA1/NUP50/IFNG/ARNTL/PRKAG1/CHP2/TNPO3/RANBP6/NPAP1/PKIA/SPRN/MBTPS1/KPNB1/APPL1/SMO/TARDBP/POM121C/SNRPG/SNRPD2	74
BP	GO:0031333	negative regulation of protein complex assembly	64/7096	139/18670	0.03163	0.1279	0.09536	MYADM/PTGER4/STMN1/THRA/BIRC2/TMSB10/GSK3B/TMOD3/TMC8/LDLRAD4/TWF2/RDX/STXBP1/ZNF451/PFN1/CAPZA2/PRKCD/ARFGEF1/CAPG/PMEPA1/ARHGEF2/CAPZA1/ANKRD27/MAPRE1/HMGB1/CLU/RAF1/MKKS/SPTBN1/CDH5/LCMT1/DDX3X/BBS4/MEFV/AVIL/KANK1/TRIOBP/ADD3/VDAC2/DMTN/CPTP/IMPACT/INSIG1/LMOD3/PEX14/ULK1/SCIN/HEY2/SLIT2/TUBB4A/DNAJC15/RIOK3/SPTA1/OPRD1/SPTBN2/TRAF3IP1/KANK3/PRKCZ/SNCA/CLIP3/IAPP/NLRC3/KIF14/ALB	64
BP	GO:0048661	positive regulation of smooth muscle cell proliferation	48/7096	101/18670	0.03165	0.1279	0.09536	IGF1/NAMPT/AKR1B1/GNAI3/PTGS2/S1PR1/STAT1/JAK2/TNF/HMOX1/SKP2/HMGCR/NOTCH3/IRAK4/PTAFR/PAK1/HPGD/P2RY6/TRAF6/AIF1/CCL5/IL6/PDGFB/PPARGC1A/BMPR1A/MMP9/GNAI2/BMP4/TGM2/HDAC4/ID2/ITGA2/CYBA/MAP3K5/EGFR/IL18/MDM2/NR4A3/HBEGF/ABCC4/MMP2/TERT/MTOR/FOXP1/ERN1/CX3CL1/SERPINF2/PDGFD	48
BP	GO:0006364	rRNA processing	95/7096	214/18670	0.03195	0.1289	0.09611	DDX21/LYAR/RPP38/TSR1/GTPBP4/WDR46/UTP14A/ISG20/ISG20L2/XRN2/NAF1/DDX49/TFB1M/KRI1/TRMT112/KRR1/TRMT61B/RPP25/RPUSD2/SIRT1/ABT1/RPS24/WDR74/NOLC1/MRTO4/NAT10/DDX24/RPS21/THUMPD1/RPS9/FBL/RRP7A/RPS19/SUV39H1/NHP2/LAS1L/UTP15/EXOSC2/GAR1/FTSJ3/RPF2/FDXACB1/RNASEL/DIMT1/ZCCHC4/WDR36/EXOSC7/RCL1/WDR75/METTL15/DCAF13/NOL8/RRP15/RIOK2/NOL10/SART1/RIOK3/ERI3/RPP40/MPHOSPH6/TEX10/MRM1/IMP4/RPS16/WBP11/EXOSC9/NOC4L/DDX18/EXOSC3/DDX27/RPL7L1/FAM207A/FBLL1/NSUN5P1/POP7/REXO4/TSR2/MDN1/DDX54/DDX10/EXOSC6/EXOSC8/MRPS9/ZNHIT6/NUDT16/NOP10/C1D/UTP3/RRS1/ESF1/PA2G4/EXOSC5/DDX52/MRPL1/RPL10A	95
BP	GO:0019048	modulation by virus of host morphology or physiology	21/7096	39/18670	0.03196	0.1289	0.09611	ATG7/TGFB1/INSR/HYAL2/KPNA4/CD209/CASP8/VAPB/BCL2L11/RXRA/CCL8/CCNK/TYMS/RRAGA/EIF2AK2/KPNA1/BAD/CD4/EIF2AK4/DAG1/KPNB1	21
BP	GO:0030204	chondroitin sulfate metabolic process	21/7096	39/18670	0.03196	0.1289	0.09611	HEXB/VCAN/CHSY1/IDS/IMPAD1/HEXA/CHST13/ARSB/CSGALNACT1/CSPG4/XYLT1/CHST11/SLC35D1/B3GALT6/IDUA/XYLT2/CSGALNACT2/SPOCK2/BCAN/CHST12/CHST7	21
BP	GO:1903428	positive regulation of reactive oxygen species biosynthetic process	29/7096	57/18670	0.03225	0.13	0.09693	KLF4/KLF2/CLEC7A/PTGS2/JAK2/TNF/DDAH2/PKD2/TICAM1/CD36/PTK2B/INSR/HBB/PTX3/TLR4/IL1B/AIF1/CLU/DNM2/HDAC4/CYBA/AGXT2/IFNG/HSP90AB1/DUOXA1/MTOR/RAB27A/TLR6/FOXO3	29
BP	GO:0002230	positive regulation of defense response to virus by host	15/7096	26/18670	0.03266	0.1311	0.09774	PARP9/STAT1/ERCC6/LILRB1/AIM2/SIN3A/DDX58/APOBEC3G/MAVS/DTX3L/IL12RB1/IL12B/TRIM6/EIF2AK4/IL23A	15
BP	GO:0002360	T cell lineage commitment	15/7096	26/18670	0.03266	0.1311	0.09774	STAT6/STAT3/LY9/BATF/IL7/IL6/CYLD/BCL2/IL12RB1/IL12B/TBX21/MTOR/RHOA/FOXN1/IL23A	15
BP	GO:0006779	porphyrin-containing compound biosynthetic process	15/7096	26/18670	0.03266	0.1311	0.09774	FECH/UROD/ALAD/ABCB6/CPOX/TMEM14C/SRRD/COX15/IREB2/NFE2L1/RSAD1/ALAS1/SPTA1/SLC25A38/SLC25A39	15
BP	GO:0034453	microtubule anchoring	15/7096	26/18670	0.03266	0.1311	0.09774	NINL/FOPNL/PCM1/BICD2/BICD1/BBS4/BCCIP/HOOK3/CCDC120/CLASP2/PEX14/CEP57/CEP19/FGFR1OP/DAG1	15
BP	GO:0051788	response to misfolded protein	15/7096	26/18670	0.03266	0.1311	0.09774	KLHL15/UBE2W/CLU/SDF2L1/TOR1A/RNF126/DERL1/STUB1/ATXN3/POMT2/RNF185/RNF5/VCP/ATXN3L/DNAJC18	15
BP	GO:0071624	positive regulation of granulocyte chemotaxis	15/7096	26/18670	0.03266	0.1311	0.09774	RAC2/CAMK1D/CD74/RAC1/C3AR1/MOSPD2/C1QBP/CXCR2/LBP/DAPK2/CCL19/TIRAP/CCR7/IL23A/S100A14	15
BP	GO:0072539	T-helper 17 cell differentiation	15/7096	26/18670	0.03266	0.1311	0.09774	NFKBIZ/STAT3/NLRP3/SMAD7/LY9/BATF/ZBTB7B/NFKBID/IL6/IL12RB1/RORA/IL12B/TBX21/MALT1/IL23A	15
BP	GO:0071322	cellular response to carbohydrate stimulus	66/7096	144/18670	0.03271	0.1311	0.09775	TRA2B/CLEC7A/GCLM/ENY2/HMGCR/LRP5/PPP3CB/SIN3A/AACS/UNC13B/FIS1/ARRB1/HIF1A/PIM3/PCK2/LEP/SRF/MAPK13/IGF1R/GCLC/AGER/C2CD2L/RAP1A/MPC2/LRP1/RAF1/TRPM4/RAC1/IRS2/ZNF236/PPARGC1A/KLF7/SRI/OXCT1/POLG/GPR27/NME1/PRKACA/LGALS1/PDX1/CYBA/PTPRN2/HMGN3/CMA1/PRKAA1/MAP2K4/BAD/PLA2G6/KIF5B/MEN1/WDR35/ZBTB20/NDUFAF2/MAP4K4/ERN1/SLC9B2/SOX4/SIDT2/GCG/ENDOG/NR1H4/STXBP4/FOXO3/GHRL/MIR146A/PHPT1	66
BP	GO:0090199	regulation of release of cytochrome c from mitochondria	25/7096	48/18670	0.03271	0.1311	0.09775	IGF1/BMF/PINK1/LMNA/PMAIP1/PRELID1/HIGD1A/HGF/TNFSF10/CHCHD10/CLU/PLAUR/PDCD5/BCL2L11/MMP9/BAX/MLLT11/DNM1L/BAD/PLA2G6/MOAP1/WDR35/GPX1/TRIAP1/BAK1	25
BP	GO:0009063	cellular amino acid catabolic process	58/7096	125/18670	0.03341	0.1336	0.09959	ASRGL1/ATP2B4/ENOSF1/HIBADH/ARG2/IL4I1/PCYOX1/HMGCL/AHCY/ALDH7A1/PHYKPL/BCKDK/ALDH6A1/PCBD1/HAL/DDAH2/HNMT/FAH/AUH/DBT/MTRR/IDO1/GSTZ1/QDPR/OGDH/ALDH4A1/ACADSB/GLUD1/PCYOX1L/DAO/ADHFE1/ALDH5A1/MCCC1/KYNU/HAAO/SHMT2/GLUD2/TST/MPST/HSD17B10/ALDH8A1/CTH/PPAT/GLS/GOT2/AGXT2/SHMT1/IDO2/AMT/BCKDHB/AMDHD1/BCAT2/BCKDHA/HYKK/HMGCLL1/TDO2/MAT1A/PIPOX	58
BP	GO:0016445	somatic diversification of immunoglobulins	32/7096	64/18670	0.03343	0.1336	0.09959	IL27RA/MAD2L2/STAT6/BCL6/CD40/PTPRC/BATF/TGFB1/UNG/SWAP70/SAMHD1/PMS2P5/XRCC4/MLH1/PARP3/ERCC1/CLCF1/CCR6/LIG4/POLL/TFRC/TNFSF4/EXO1/PMS2P3/EXOSC3/MCM3AP/POLB/TBX21/APLF/EXOSC6/PAXIP1/ATAD5	32
BP	GO:0030032	lamellipodium assembly	32/7096	64/18670	0.03343	0.1336	0.09959	RAC2/SPATA13/S1PR1/VCL/PTPRO/TWF2/NUP85/PARVB/NCK1/ARHGEF6/P2RY12/RAC1/CCDC88A/CYFIP1/SRGAP2/ABLIM3/DNM2/HDAC4/FER/DMTN/BIN3/SLIT2/FSCN1/WNT1/ATP7A/HRG/ARPC2/MTOR/ARHGEF4/WAS/NCKAP1/ABLIM1	32
BP	GO:0035773	insulin secretion involved in cellular response to glucose stimulus	32/7096	64/18670	0.03343	0.1336	0.09959	ENY2/HMGCR/LRP5/PPP3CB/ARRB1/HIF1A/PIM3/C2CD2L/MPC2/LRP1/RAF1/TRPM4/RAC1/KLF7/SRI/OXCT1/GPR27/PDX1/PTPRN2/HMGN3/BAD/PLA2G6/KIF5B/NDUFAF2/MAP4K4/SLC9B2/SIDT2/GCG/NR1H4/STXBP4/GHRL/PHPT1	32
BP	GO:0048278	vesicle docking	32/7096	64/18670	0.03343	0.1336	0.09959	STX7/STX11/CTBP2/EXOC6B/STXBP1/UNC13B/STXBP2/VAMP3/VPS33A/BLOC1S6/RAB8A/STX5/VPS18/STX16/PLEK/CAMK2A/YKT6/RAB8B/RAB3A/STX12/PPFIA3/CEP83/VTI1B/SYTL2/EXOC4/STX8/SYT1/RAB3B/SCFD1/STXBP3/RABEPK/RAB3D	32
BP	GO:0007611	learning or memory	112/7096	256/18670	0.03357	0.1341	0.09995	CRHBP/NRGN/FOS/FYN/CX3CR1/TLR2/LILRB2/PRKAR2B/ITGA5/ATP8A1/NTAN1/THRA/PTGS2/GM2A/LGMN/CEBPB/SLC7A11/EPHB2/KRAS/APOE/HMGCR/BTG2/ACTR2/CIC/PPP3CB/CLN8/HIF1A/ARF4/SYNJ1/SRF/INSR/FZD9/CDK5/PLK2/CASP3/PAFAH1B1/CLN3/S100B/AGER/LDLR/GATM/TIFAB/CREB1/NPTN/EIF4EBP2/TTBK1/EGR2/KALRN/ARC/CRTC1/ADCY1/ADCY3/RGS14/KCNAB1/SYNGAP1/SHANK1/KCNK2/CPEB3/ITGA3/BHLHB9/NPAS4/VDAC1/RASGRF1/ABCA7/GRPR/PLCB1/EGFR/C1QL1/ATXN1L/SLC8A2/MAP1A/KAT2A/PSEN1/MAPK1/CHRNB2/IFT20/PLA2G6/ITGA8/FOSL1/VIP/ATXN1/RIN1/DBH/EIF2AK4/SYT4/KMT2B/PRKCZ/OPRL1/RELN/VDAC3/MTOR/BRSK1/APP/SHC3/SLC24A2/PTPRZ1/LMX1A/FGF13/ATP1A2/SLC8A3/PICALM/CTNS/ATAD1/SHANK3/FEN1/AAAS/TACR2/NTSR1/NTRK2/MEF2C/SYNPO/STRA6	112
BP	GO:0043648	dicarboxylic acid metabolic process	47/7096	99/18670	0.03388	0.1352	0.1008	QPRT/GCLM/MDH1/MTHFD2/FOLR2/PHYH/ME1/SLC7A11/HAL/ALDH18A1/NAGS/ACLY/MTRR/GCLC/ME3/OGDH/IDH1/ALDH4A1/GLUD1/ADHFE1/ALDH5A1/IDH2/KYNU/HAAO/SLC25A12/SHMT2/GLUD2/ATIC/FH/MDH1B/SLC46A1/GLS/GOT2/SUCLG2/SHMT1/DHFR/FPGS/AMDHD1/L2HGDH/SDHA/ALDH1L1/GRHPR/ME2/SLC25A32/ATCAY/NR1H4/ACOT8	47
BP	GO:0090068	positive regulation of cell cycle process	129/7096	298/18670	0.03411	0.136	0.1014	IGF1/ANXA1/CDKN1A/WNT5A/CCND3/NUP62/RAB11A/MEPCE/DYNC1LI1/DDRGK1/RGCC/EZH2/LSM11/PAF1/PKD2/BTG2/CCND2/TMOD3/LRP5/CDK4/KIF3B/TGFB1/RDX/SMC5/SIN3A/MTA3/INSR/DBF4B/UBXN2B/PLK2/SVIL/SFN/NPM1/RAD51B/IL1B/AIF1/NSMCE2/NSFL1C/RAB11FIP4/PML/PHIP/SPAG5/SFPQ/CCND1/PDGFB/RHNO1/UHRF2/ESPL1/DDX3X/ATM/TNKS1BP1/MIR34A/ANAPC5/MUC1/SPHK1/KMT2E/MYOG/PLK3/MYBBP1A/UBE2E2/CCNE1/NDC80/PCNA/BAX/ANKRD17/CRADD/ID2/CASP2/CDKN1B/KIF20B/PRKACA/CNOT4/IL1A/CDC25A/PLAGL1/GEN1/ARID3A/NUSAP1/VPS4B/FOXO4/UBE2C/DTL/MED25/DYRK3/E2F4/PLCB1/BRCA1/EGFR/CNOT7/GML/GPSM2/PKN2/ADAM17/RCC2/MDM2/DLGAP5/EIF4G1/ANAPC4/RBL2/MTBP/CUL4B/PCID2/RB1/PPP2R5B/CNOT10/CARM1/MSX1/TERT/CEP120/ANKRD31/RHOA/TRIAP1/AURKA/ANAPC11/APP/CDC73/SOX4/USP19/CSPP1/PRMT1/NUDT16/ATAD5/ROCK2/UBE2B/WNT10B/STXBP4/FEN1/KIF14/E2F8	129
BP	GO:0071479	cellular response to ionizing radiation	35/7096	71/18670	0.03412	0.136	0.1014	NAMPT/CDKN1A/RAD51AP1/EGR1/RAD1/TGFB1/INTS7/TMEM109/NET1/HSPA5/HRAS/XRCC5/SIRT1/RHNO1/ATM/TNKS1BP1/DNM2/SWI5/TSPYL5/GRB2/CYBA/LIG4/ZMPSTE24/KDM4D/FBXO4/ATR/CLOCK/HAMP/MDM2/XRCC6/RAD9A/MGMT/NUCKS1/SPIDR/FIGNL1	35
BP	GO:0030201	heparan sulfate proteoglycan metabolic process	20/7096	37/18670	0.03424	0.1362	0.1016	HS3ST2/EXTL2/NDST2/HS2ST1/EXT2/EXT1/SGSH/CSGALNACT1/XYLT1/B3GALT6/GLCE/SULF2/XYLT2/HPSE/NDST1/HS3ST1/HS3ST3B1/TCF7L2/B3GAT3/HS3ST6	20
BP	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	20/7096	37/18670	0.03424	0.1362	0.1016	MYADM/S100A10/NEDD9/FLNA/CIB1/ABL1/CRK/RAC1/DOCK5/NRP1/DNM2/UNC13D/TRIOBP/DMTN/CALR/C1QBP/PREX1/APOA1/ARPC2/LIMS1	20
BP	GO:2000249	regulation of actin cytoskeleton reorganization	20/7096	37/18670	0.03424	0.1362	0.1016	NOTCH2/HCK/F11R/ARHGDIA/HCLS1/TGFB1/PTK2B/GMFG/BAIAP2/ARHGDIB/CDK5/HRAS/ABL1/TRPM2/NRP1/BCAS3/CD2AP/ABL2/CSF1R/PHPT1	20
BP	GO:1903313	positive regulation of mRNA metabolic process	38/7096	78/18670	0.03444	0.1366	0.1018	TRA2B/ZFP36/TOB1/AGO2/PAF1/YTHDF3/MOV10/HNRNPR/METTL14/GIGYF2/BTG2/DAZAP1/THRAP3/METTL3/ZC3H12D/RBMXL1/RBM3/ZC3HAV1/FTO/GTPBP1/PRDX6/CPEB1/TNRC6B/SF3B4/TNRC6A/HNRNPD/CPEB3/LEO1/CNOT7/ZFP36L2/PRPF19/CELF3/HMX2/CDC73/PNPT1/ROCK2/PLEKHN1/UPF1	38
BP	GO:0002028	regulation of sodium ion transport	41/7096	85/18670	0.03446	0.1366	0.1018	SLC8A1/ATP2B4/ATP1A1/KLHL24/CHP1/NETO2/ACTN4/SIK1/YWHAH/P2RX7/SLC9A1/FXYD5/TESC/FXYD6/TGFB1/SCN1B/DMD/ATP1B2/ATP1B3/ARF1/FXYD1/DNM2/NEDD4/ATP1B1/ADRB2/RANGRF/SCN2B/COMMD1/CAMK2D/AHCYL1/CAV3/NKAIN4/FXYD7/PKP2/FXYD2/KIF5B/SNTA1/FXYD3/ATP1A2/CNTN1/WNK2	41
BP	GO:0021904	dorsal/ventral neural tube patterning	14/7096	24/18670	0.03449	0.1366	0.1018	TCTN1/PRKACB/TULP3/WDR19/GORAB/BMP4/PRKACA/MKS1/PSEN1/GPR161/TRAF3IP1/PAX7/SMO/PTCH1	14
BP	GO:0042832	defense response to protozoan	14/7096	24/18670	0.03449	0.1366	0.1018	GBP2/CLEC7A/SLC11A1/CD40/IL4R/BATF/CCDC88B/GBP4/TSPAN32/HRAS/BATF2/IRF8/GBP6/IL12B	14
BP	GO:0046697	decidualization	14/7096	24/18670	0.03449	0.1366	0.1018	JUNB/VDR/PTGS2/SPP1/PPARD/EPOR/CTSB/ASH1L/CTSV/MAPK1/CYP27B1/MEN1/GJA1/GHRL	14
BP	GO:0046835	carbohydrate phosphorylation	14/7096	24/18670	0.03449	0.1366	0.1018	HK3/GNPTG/PFKFB3/GALK1/NAGK/GNPTAB/FGGY/PFKFB4/KHK/PFKFB1/PFKFB2/IPPK/GNE/RBKS	14
BP	GO:0071218	cellular response to misfolded protein	14/7096	24/18670	0.03449	0.1366	0.1018	KLHL15/UBE2W/SDF2L1/TOR1A/RNF126/DERL1/STUB1/ATXN3/POMT2/RNF185/RNF5/VCP/ATXN3L/DNAJC18	14
BP	GO:0090023	positive regulation of neutrophil chemotaxis	14/7096	24/18670	0.03449	0.1366	0.1018	RAC2/CAMK1D/CD74/RAC1/C3AR1/MOSPD2/C1QBP/CXCR2/LBP/DAPK2/CCL19/TIRAP/CCR7/IL23A	14
BP	GO:0002011	morphogenesis of an epithelial sheet	28/7096	55/18670	0.03467	0.137	0.1021	MPP5/WNT5A/ITGA5/FLNA/RHOC/CD44/DVL2/MEGF8/SRF/CD151/MMP12/BMP7/ARHGAP12/TOR1A/BMP5/CLASP2/LIN7C/ADAM17/DVL1/HBEGF/PHACTR4/TMEFF2/MTOR/RHOA/DAG1/PDCD10/WNT7A/LAMA1	28
BP	GO:0006576	cellular biogenic amine metabolic process	28/7096	55/18670	0.03467	0.137	0.1021	SMS/OAZ2/GDE1/ALDH7A1/HNMT/SAT1/NAPEPLD/OAZ3/MAOA/IDO1/ODC1/KYNU/HAAO/HDAC10/BHMT/AZIN1/CHKA/TPH2/IDO2/SRM/ATP7A/SULT1B1/DBH/AZIN2/CHDH/AGMAT/DHPS/TDO2	28
BP	GO:0032781	positive regulation of ATPase activity	28/7096	55/18670	0.03467	0.137	0.1021	PLSCR1/CHTOP/UHRF1/PFN1/DNAJB1/DYNLL2/SETMAR/DNAJC19/MYBPC3/DHX9/ATP1B2/DNAJC1/DNAJB6/SUMO1/ATP1B3/GTF2H4/DNAJB4/NAPA/DNM2/TPM1/ATP1B1/DNAJC10/DNAL4/DNAJC15/RAB3A/HSCB/DNAJA1/DNAJC24	28
BP	GO:0042157	lipoprotein metabolic process	60/7096	130/18670	0.03469	0.137	0.1021	ATG7/ZDHHC20/NMT2/CTSD/ABHD13/LYPLAL1/ABHD12/PIGV/PIGP/ABHD17C/APOC1/APOL6/PIGK/APOE/LYPLA2/ZDHHC9/PIGN/LEP/RAB3GAP1/ABCA1/ZDHHC6/LDLR/LRP1/WIPI1/PIGF/DGAT2/PIGB/DPM1/ZDHHC5/GPAA1/APOL1/APOA5/ATM/PIGM/APOL3/LCAT/MPPE1/HHAT/APOL2/PIGQ/WDR45B/ZDHHC16/PIGO/UGCG/PIGH/ZDHHC14/PPARA/DPM3/ZDHHC2/APOA1/ZDHHC18/PIGT/APOL4/CLIP3/APOL5/ZDHHC12/ZDHHC21/PGAP3/PGAP1/ATG12	60
BP	GO:0090501	RNA phosphodiester bond hydrolysis	70/7096	154/18670	0.0347	0.137	0.1021	RNASE2/PCF11/RNASEH2B/AGO2/DIS3L/RPP38/MOV10/CSTF3/SND1/TSN/RNASE3/RNASE1/ANGEL1/ISG20/ISG20L2/XRN2/HELZ2/PIWIL4/TOE1/KRI1/LACTB2/RNASE6/SAMHD1/DCP2/RPP25/ELAC1/ABT1/USB1/MRPL44/SLFN13/CPSF3/RPP14/RPS21/RNASEH1/DICER1/DCPS/NHP2/FIP1L1/XRN1/REXO2/EXOSC2/AGO1/RNASEL/EXOSC7/RCL1/CNOT7/ERI3/RPP40/EXO1/DIS3L2/EXOSC9/EXOSC3/RPPH1/POP7/CPSF2/DROSHA/ERN1/EXOSC6/CPSF1/PNPT1/CPSF7/EXOSC8/NUDT16/ENDOG/POLR2I/RRS1/FEN1/POLR3K/ENDOV/EXOSC5	70
BP	GO:0007034	vacuolar transport	65/7096	142/18670	0.03482	0.1374	0.1024	ATP6V0D2/GRN/PINK1/C9orf72/NCOA4/FAM160A2/ATG14/LAMP2/PSAP/LAMP1/VPS37B/VPS13A/M6PR/VPS41/CHMP4B/ARSB/NAGPA/GNPTAB/DENND3/TRAK2/IGF2R/VPS33A/VPS37C/LRP1/CLU/HOOK2/TMEM106B/GOSR2/LRRK2/SNX27/ARF1/DTX3L/VPS13D/HOOK3/VPS18/VPS51/NEDD4/CHMP2A/TSG101/ADRB2/VIPAS39/HGS/KIF13A/VPS52/VTI1A/CHMP1A/VPS4B/RAB7B/GPRASP1/VPS25/AP3B1/AP1G1/VTI1B/AP3M1/STX8/TRAK1/TMEM50A/EHD3/CLEC16A/VPS16/VCP/CHMP1B/SNX16/CCDC91/BIN1	65
BP	GO:0006406	mRNA export from nucleus	52/7096	111/18670	0.03501	0.1379	0.1028	NXF1/SRSF5/NUP62/NUP160/CHTOP/NUP214/ENY2/AGFG1/ALYREF/RNPS1/MAGOHB/SARNP/NUP85/NXT1/SEH1L/YTHDC1/NUP43/HNRNPA2B1/RBM8A/FYTTD1/DDX19B/U2AF1/POM121/SRSF3/SYMPK/CPSF3/FIP1L1/NUP88/THOC2/SRSF6/SRSF7/NUP107/CDC40/THOC5/POLR2D/U2AF1L4/EIF5A/NUP93/THOC6/SRRM1/NUP205/SRSF4/EIF4E/NUP50/DHX38/MCM3AP/PCID2/CPSF2/CPSF1/POM121C/AAAS/UPF1	52
BP	GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus	52/7096	111/18670	0.03501	0.1379	0.1028	NXF1/SRSF5/NUP62/NUP160/CHTOP/NUP214/ENY2/AGFG1/ALYREF/RNPS1/MAGOHB/SARNP/NUP85/NXT1/SEH1L/YTHDC1/NUP43/HNRNPA2B1/RBM8A/FYTTD1/DDX19B/U2AF1/POM121/SRSF3/SYMPK/CPSF3/FIP1L1/NUP88/THOC2/SRSF6/SRSF7/NUP107/CDC40/THOC5/POLR2D/U2AF1L4/EIF5A/NUP93/THOC6/SRRM1/NUP205/SRSF4/EIF4E/NUP50/DHX38/MCM3AP/PCID2/CPSF2/CPSF1/POM121C/AAAS/UPF1	52
BP	GO:0072676	lymphocyte migration	52/7096	111/18670	0.03501	0.1379	0.1028	MYO1G/CCR2/IL27RA/OXSR1/WNT5A/ITGB7/TNFRSF14/S1PR1/CXCL11/ADAM8/CXCL10/CXCL12/DOCK8/PTK2B/CXCL13/ITGA4/CD99/AIF1/CCL5/CRK/CCL7/CD200R1/CKLF/SLC12A2/CCL13/CD99L2/TMEM102/CCL8/PIK3CD/CCR6/MADCAM1/CH25H/GCSAM/GPR15/FADD/ADAM17/CCL20/CCL26/MSN/RET/C10orf99/PIK3CG/TBX21/RHOA/APP/GPR183/CX3CL1/CXCR3/CCL19/CCL4/CCR7/CCL24	52
BP	GO:0044003	modification by symbiont of host morphology or physiology	24/7096	46/18670	0.03515	0.1383	0.1031	SERPINB9/ATG7/GAPDH/TGFB1/INSR/HYAL2/KPNA4/CD209/CASP8/VAPB/BCL2L11/RXRA/CCL8/TNIP1/CCNK/TYMS/RRAGA/EIF2AK2/KPNA1/BAD/CD4/EIF2AK4/DAG1/KPNB1	24
BP	GO:0006892	post-Golgi vesicle-mediated transport	49/7096	104/18670	0.0357	0.1404	0.1047	CSK/GGA2/TRIM23/VAMP5/LAMP1/SYS1/EXOC6B/RAB31/VPS13A/SCAMP2/EXOC1/ARF4/MYO5A/ARF5/GOPC/VAMP3/SCAMP1/C16orf70/RP2/CNST/WIPI1/BBS2/PREPL/SPTBN1/GOSR2/KIF16B/ARF1/GOLPH3L/DNM2/CCDC93/KIF13A/VPS52/VTI1A/ARFRP1/AP2A1/COMMD1/RABEP1/AP1G1/VTI1B/EXOC4/LLGL1/EHD3/SCFD1/OPTN/CCDC91/ARF3/RAB26/MACF1/EXOC2	49
BP	GO:0001889	liver development	62/7096	135/18670	0.03591	0.1409	0.105	ANXA1/ARF6/SRSF5/SRD5A1/HMGCL/TNFAIP3/LSR/DBP/CEBPG/FBXW7/CEBPB/HFE/EZH2/HMOX1/PKD2/KRAS/PKM/RELA/CSNK2A2/TGFB1/AACS/HMGCS1/HGF/PCK2/CEBPA/IGF2R/RAP1A/QDPR/CSNK2B/CCND1/MESP1/GNPNAT1/CITED2/SULF2/PCNA/MPST/ASNS/ITGA2/TYMS/PDX1/RHBDD3/HNRNPD/PRMT5/HES1/ZMPSTE24/ADA/HLX/EGFR/WNT1/HAMP/FPGS/HNF1B/CAD/HNF1A/ATP7A/WDR35/HPN/AURKA/MET/PNPT1/PTCH1/E2F8	62
BP	GO:0071331	cellular response to hexose stimulus	62/7096	135/18670	0.03591	0.1409	0.105	TRA2B/GCLM/ENY2/HMGCR/LRP5/PPP3CB/SIN3A/AACS/UNC13B/FIS1/ARRB1/HIF1A/PIM3/PCK2/SRF/IGF1R/GCLC/AGER/C2CD2L/RAP1A/MPC2/LRP1/RAF1/TRPM4/RAC1/IRS2/ZNF236/PPARGC1A/KLF7/SRI/OXCT1/POLG/GPR27/NME1/PRKACA/LGALS1/PDX1/CYBA/PTPRN2/HMGN3/CMA1/PRKAA1/BAD/PLA2G6/KIF5B/MEN1/WDR35/ZBTB20/NDUFAF2/MAP4K4/ERN1/SLC9B2/SOX4/SIDT2/GCG/ENDOG/NR1H4/STXBP4/FOXO3/GHRL/MIR146A/PHPT1	62
BP	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	31/7096	62/18670	0.03594	0.1409	0.105	AIFM1/ERP29/PTPN2/TMBIM6/PPP1R15A/PMAIP1/CEBPB/ATF4/UBE2K/ITPR1/TMEM117/WFS1/NCK1/PML/SIRT1/LRRK2/BCL2L11/TXNDC12/SERINC3/BCL2/BAX/DNAJC10/CREB3/PDX1/MAP3K5/TNFRSF10B/TRAF2/CASP4/HYOU1/ERN1/BAK1	31
BP	GO:1902305	regulation of sodium ion transmembrane transport	31/7096	62/18670	0.03594	0.1409	0.105	ATP2B4/KLHL24/CHP1/NETO2/ACTN4/YWHAH/SLC9A1/FXYD5/TESC/FXYD6/SCN1B/DMD/ATP1B2/ATP1B3/ARF1/FXYD1/DNM2/NEDD4/ATP1B1/RANGRF/SCN2B/COMMD1/CAMK2D/CAV3/FXYD7/FXYD2/KIF5B/SNTA1/FXYD3/ATP1A2/WNK2	31
BP	GO:0007044	cell-substrate junction assembly	46/7096	97/18670	0.03628	0.1409	0.105	S100A10/FN1/TSC1/ITGA5/PLEC/TRIP6/LDB1/SLC9A1/DUSP3/PEAK1/TLN1/PTK2B/ACTN1/LAMB3/VEGFA/ABL1/CD151/TESK2/LRP1/PPM1F/SLK/RAC1/PTK2/ARHGAP6/BCR/LIMCH1/NRP1/BCL2/WDPCP/BCAS3/ITGA2/MMP14/DMTN/CORO1C/CLASP2/RCC2/HRG/MAP4K4/RHOA/KRT14/LIMS1/ITGB1BP1/ROCK2/MACF1/PTPRJ/FMN1	46
BP	GO:0010771	negative regulation of cell morphogenesis involved in differentiation	46/7096	97/18670	0.03628	0.1409	0.105	RTN4R/DNM3/WNT5A/GBP1/SEMA4B/SPP1/ULK2/ACTN4/YWHAH/EPHB2/ARHGDIA/IFRD1/PTPRO/UBE3A/RAPGEF2/SEMA4A/CDK5/TRAK2/GDI1/SEMA4C/SEMA4D/DCC/PTK2/SEMA6B/NRP1/SEMA3B/KANK1/SYNGAP1/DAB1/SEMA5A/DMTN/FSTL4/CORO1C/RCC2/SLIT2/PSEN1/SEMA5B/RUFY3/PLXNA3/TACSTD2/RHOA/RTN4/ITGB1BP1/FGF13/LRP4/TRIM46	46
BP	GO:1990868	response to chemokine	46/7096	97/18670	0.03628	0.1409	0.105	CCR2/CX3CR1/DUSP1/OXSR1/CIB1/PPBP/ACKR3/CXCL9/CXCL11/CXCL10/CXCL12/DOCK8/HIF1A/PTK2B/CXCL13/CMKLR1/CCL5/RNF113A/CCL7/CXCR1/CCR5/SLC12A2/CCL13/CCL8/CCR6/CXCR6/CCR4/CCR3/CXCR2/CCL20/SLIT2/CCL26/GPR35/TREM2/RHOA/CX3CL1/CXCR3/CCL19/CCL4/CCR7/CCL24/ACKR2/CCRL2/CXCL6/THPO/SLIT3	46
BP	GO:1990869	cellular response to chemokine	46/7096	97/18670	0.03628	0.1409	0.105	CCR2/CX3CR1/DUSP1/OXSR1/CIB1/PPBP/ACKR3/CXCL9/CXCL11/CXCL10/CXCL12/DOCK8/HIF1A/PTK2B/CXCL13/CMKLR1/CCL5/RNF113A/CCL7/CXCR1/CCR5/SLC12A2/CCL13/CCL8/CCR6/CXCR6/CCR4/CCR3/CXCR2/CCL20/SLIT2/CCL26/GPR35/TREM2/RHOA/CX3CL1/CXCR3/CCL19/CCL4/CCR7/CCL24/ACKR2/CCRL2/CXCL6/THPO/SLIT3	46
BP	GO:0006085	acetyl-CoA biosynthetic process	13/7096	22/18670	0.03631	0.1409	0.105	PDK4/PDK2/ACLY/GSTZ1/MPC2/MLYCD/PDK1/PDHB/DLAT/PDP2/PDHA2/PDP1/PDPR	13
BP	GO:0006925	inflammatory cell apoptotic process	13/7096	22/18670	0.03631	0.1409	0.105	NOD2/ANXA1/IRF7/SLC7A11/CCL5/SIRT1/IL6/CCR5/PIK3CD/ZMPSTE24/CXCR2/MEF2C/PIK3CB	13
BP	GO:0009235	cobalamin metabolic process	13/7096	22/18670	0.03631	0.1409	0.105	MMADHC/ABCD4/MTR/CD320/MTRR/PRSS3/MMAB/MMACHC/CTRB2/LMBRD1/CLYBL/TCN1/CTRC	13
BP	GO:0032656	regulation of interleukin-13 production	13/7096	22/18670	0.03631	0.1409	0.105	ARG2/IL17RA/LILRA5/NLRP3/TNFRSF21/IL1RAP/HLA-E/SCGB1A1/LGALS9/TNFSF4/TSLP/PRKCZ/IL17RB	13
BP	GO:0032727	positive regulation of interferon-alpha production	13/7096	22/18670	0.03631	0.1409	0.105	IRF7/STAT1/TLR4/DDX58/DHX9/MMP12/HMGB1/MAVS/IFIH1/TLR8/TLR3/CHUK/HMGB4	13
BP	GO:0033622	integrin activation	13/7096	22/18670	0.03631	0.1409	0.105	FN1/PTGER4/FBLIM1/CXCL12/TLN1/CXCL13/P2RY12/PLEK/CDH17/SKAP1/CX3CL1/ITGB1BP1/KIF14	13
BP	GO:0034311	diol metabolic process	13/7096	22/18670	0.03631	0.1409	0.105	ASAH1/GCH1/PCBD1/SGPP2/SPTLC2/QDPR/PTS/SPR/SPHK1/DHFR/ACER3/PCBD2/DEGS2	13
BP	GO:0042094	interleukin-2 biosynthetic process	13/7096	22/18670	0.03631	0.1409	0.105	CLEC7A/ZFP36/PTPRC/IL1RAP/IL1B/GLMN/IL1A/LAG3/IL18/CD4/CD80/PRKCQ/CD3E	13
BP	GO:0044321	response to leptin	13/7096	22/18670	0.03631	0.1409	0.105	STAT3/ADIPOR1/LEP/BBS2/SIRT1/MKKS/CCND1/BBS4/UGCG/PID1/NR4A3/CCNA2/FGF23	13
BP	GO:0071359	cellular response to dsRNA	13/7096	22/18670	0.03631	0.1409	0.105	FLOT1/P2RX7/NFKB1/DDX58/NPM1/DHX9/MAVS/IFIH1/IFIT1/MUL1/RIOK3/TLR3/ZCCHC3	13
BP	GO:0097320	plasma membrane tubulation	13/7096	22/18670	0.03631	0.1409	0.105	FCHO1/PACSIN2/FCHO2/PLEKHM2/MICALL1/SNX33/BIN2/DNM2/BIN3/SH3GLB1/SNX9/ASAP1/PACSIN3	13
BP	GO:1901685	glutathione derivative metabolic process	13/7096	22/18670	0.03631	0.1409	0.105	MGST2/GSTP1/ESD/AKR1A1/GSTO1/GSTZ1/GSTA1/GSTM3/MGST1/GSTM5/HPGDS/GSTM4/MGST3	13
BP	GO:1901687	glutathione derivative biosynthetic process	13/7096	22/18670	0.03631	0.1409	0.105	MGST2/GSTP1/ESD/AKR1A1/GSTO1/GSTZ1/GSTA1/GSTM3/MGST1/GSTM5/HPGDS/GSTM4/MGST3	13
BP	GO:1901984	negative regulation of protein acetylation	13/7096	22/18670	0.03631	0.1409	0.105	SPI1/GSK3B/SIN3A/ZNF451/SIRT1/HDAC2/NOC2L/BRCA1/HINT2/SET/SNCA/KLF15/TAF7	13
BP	GO:2000736	regulation of stem cell differentiation	54/7096	116/18670	0.03656	0.1416	0.1056	STAT3/PSMB9/PSMB8/CBFB/LDB1/PSMA5/PSMD11/PSME1/LMO2/PSMB10/PSMA1/PSMA4/METTL3/TCF12/ABL1/PSMB1/PSMC4/LTBP3/PSMD13/PSMB3/BMP7/TAL1/PSMB5/PSMD6/PSMC3/N4BP2L2/PSME3/BMP4/PSMC6/OSM/TEAD2/HES1/NFE2L2/PWP1/EIF2AK2/PSMC1/ZFP36L2/PSMD8/PSMA2/TACSTD2/SOX5/PSMC5/TRIM6/ESRRB/PSMC2/PSMB2/PSMD4/PUS7/PSMD1/PSMB4/LBH/PSMD9/PSMD3/MIR146A	54
BP	GO:0030166	proteoglycan biosynthetic process	34/7096	69/18670	0.03666	0.1416	0.1056	IGF1/HS3ST2/VCAN/EXTL2/CHSY1/NDST2/HS2ST1/EXT2/EXT1/CHST13/FAM20B/CSGALNACT1/CSPG4/CYTL1/XYLT1/CHST11/SLC35D1/B3GALT6/GLCE/CHST14/XYLT2/GAL3ST4/NDST1/CSGALNACT2/HS3ST1/BCAN/HS3ST3B1/TCF7L2/CHST12/B3GAT3/HS3ST6/BMPR1B/CHST7/BMPR2	34
BP	GO:0050771	negative regulation of axonogenesis	34/7096	69/18670	0.03666	0.1416	0.1056	RTN4R/WNT5A/SEMA4B/SPP1/ULK2/EPHB2/ARHGDIA/IFRD1/PTPRO/SEMA4A/CDK5/TRAK2/GDI1/SEMA4C/SEMA4D/DCC/PTK2/SEMA6B/NRP1/SEMA3B/SYNGAP1/DAB1/SEMA5A/FSTL4/SLIT2/PSEN1/SEMA5B/RUFY3/PLXNA3/RHOA/RTN4/FGF13/LRP4/TRIM46	34
BP	GO:0033363	secretory granule organization	19/7096	35/18670	0.03667	0.1416	0.1056	BLOC1S2/RFX2/AGFG1/PAFAH1B1/ABCA1/DTNBP1/CREB1/RAB38/PLA2G3/TBC1D20/BLOC1S3/TXNDC8/F2R/BLOC1S1/ACRBP/TBPL1/SRGN/SNX19/SYT4	19
BP	GO:0034142	toll-like receptor 4 signaling pathway	19/7096	35/18670	0.03667	0.1416	0.1056	ITGAM/APPL2/LYN/TNFAIP3/LY96/LILRA2/NFKBIA/TLR4/PTPN22/MFHAS1/NR1H3/TNIP3/WDFY1/RAB7B/LBP/TIRAP/APPL1/NR1H4/S100A14	19
BP	GO:0042455	ribonucleoside biosynthetic process	19/7096	35/18670	0.03667	0.1416	0.1056	UPP1/GMPS/ADK/GUK1/IMPDH1/CTPS2/CMPK1/PRTFDC1/NME3/MTAP/NME4/NME1/ADA/UCK1/CTPS1/CAD/UCKL1/UPP2/ADAL	19
BP	GO:0051294	establishment of spindle orientation	19/7096	35/18670	0.03667	0.1416	0.1056	SPDL1/MAP4/UBXN2B/PAFAH1B1/CDK5RAP2/SAPCD2/NSFL1C/ARHGEF2/BCCIP/NDC80/NDEL1/ZW10/SPRY1/MOS/GPSM2/SPRY2/LLGL1/CENPA/MISP	19
BP	GO:1904031	positive regulation of cyclin-dependent protein kinase activity	19/7096	35/18670	0.03667	0.1416	0.1056	CDKN1A/CCND3/RGCC/PKD2/CCND2/PSRC1/CCND1/TTBK1/PDGFB/CDKN1B/CCNK/CDK5R2/EGFR/CCNY/ADAM17/CCNYL1/HSP90AB1/CCNT1/CCNYL2	19
BP	GO:0030641	regulation of cellular pH	43/7096	90/18670	0.03672	0.1416	0.1056	ATP6V0D2/GRN/SLC11A1/SLC9A9/ATP6AP1/DMXL1/CHP1/ATP6V1C1/ATP6V0C/SLC9A1/AQP11/TCIRG1/CLCN3/ATP6V1A/CLN3/VPS33A/RAB20/ATP6V1G3/ATP6V1B2/SLC9A8/LRRK2/RAB38/SLC9A7/ATP6V1D/ROGDI/ATP6AP1L/MAFG/BCL2/ATP6V0E2/CLN6/CLN5/SLC4A5/ATP6V1G2/MAPK1/SLC4A7/SLC4A1/ATP6V1B1/TM9SF4/SLC4A11/SLC9C2/SLAMF8/SLC4A3/DMXL2	43
BP	GO:0034333	adherens junction assembly	43/7096	90/18670	0.03672	0.1416	0.1056	S100A10/TSC1/SMAD7/TRIP6/LDB1/VCL/SLC9A1/DUSP3/PEAK1/PTK2B/ACTN1/VEGFA/ABL1/TESK2/LRP1/PPM1F/SLK/RAC1/PTK2/ARHGAP6/BCR/LIMCH1/NRP1/BCL2/ZNF703/WDPCP/BCAS3/ITGA2/HIPK1/MMP14/DMTN/CORO1C/CLASP2/RCC2/HRG/MAP4K4/RHOA/LIMS1/ITGB1BP1/ROCK2/MACF1/PTPRJ/FMN1	43
BP	GO:0007059	chromosome segregation	138/7096	321/18670	0.03684	0.142	0.1059	KLHDC8B/DUSP1/MAD2L2/NUP62/RAB11A/DYNC1LI1/FBXW7/CCNB1IP1/SETDB2/SPDL1/RAN/ERCC4/ACTR2/CHMP4B/CSNK2A2/PSRC1/REC8/MEI1/CENPW/SMC5/SMC6/SEH1L/PDS5A/LATS1/CENPE/NAA10/NUP43/RMI2/USP9X/KLHL22/CDK5RAP2/CCDC155/DSCC1/NSMCE2/CENPT/KIF4A/CENPN/SKA2/SPAG5/SMARCAD1/SFPQ/MIS12/SLC25A5/CDC23/RCC1/ESPL1/ZNF207/CENPC/PUM2/LCMT1/DDX3X/SMC2/ATM/ANAPC5/CHAMP1/BANF1/NCAPD3/BUB3/PHF23/NTMT1/ARL8A/AKAP8/SPICE1/CCNE1/NDC80/MLH1/CHMP2A/RGS14/CTCF/RMI1/TLK1/TOP2B/DSN1/NDEL1/NUF2/GEN1/M1AP/NUSAP1/INCENP/ZW10/CHMP1A/SRPK1/VPS4B/CENPK/ACTR3/MOS/TUBG2/CDC26/PMF1/STAG3/BRCA1/RCC2/SYCE3/RIOK2/RIOK3/FANCM/DLGAP5/KIF2C/ERCC2/SMC3/SPC25/KATNB1/ANAPC4/DIS3L2/RNF212B/MKI67/CDC27/CDC20/UBE2I/FANCD2/PCID2/RB1/STAG1/TEX15/CDCA2/ANKRD31/ANAPC11/STAG3L3/TOP1/BEX4/IK/TOP3B/KPNB1/MCMBP/MSTO1/CHMP1B/UBE2B/RRS1/FEN1/CEP85/KIF14/BOD1/HORMAD1/PRC1/TOP2A/ARL8B/SKA3/NAA60	138
BP	GO:0006874	cellular calcium ion homeostasis	193/7096	458/18670	0.03685	0.142	0.1059	SLC8A1/FPR2/HTR2B/VDR/FPR1/CCR2/FYN/CX3CR1/PTGER4/PTPN6/S1PR4/HEXB/ATP2B4/LYN/CD55/WNT5A/MCOLN1/S1PR3/PTGER2/TPCN1/DIAPH1/TMBIM6/GNB1/S1PR1/CD40/GNA15/ACKR3/P2RY8/CXCL9/JAK2/CXCL11/PTPRC/P2RX7/BCAP31/KCTD17/CXCL10/PKD2/APOE/CXCL12/ATF4/TGFB1/ITPR1/FIS1/WFS1/CD36/LPAR2/PTK2B/MYO5A/SWAP70/CORO1A/P2RY6/MCU/CXCL13/TCIRG1/RYR1/FZD9/CDK5/ABL1/CMKLR1/STIM2/GSTO1/CLN3/CCL5/PLCG2/PML/CYSLTR1/ATP2C1/LRP1/HMGB1/DMD/VAPB/CCL7/TRPM4/NPTN/ATP7B/AFG3L2/TRPM2/PDZD8/LPAR6/CXCR1/LCK/CDH5/CCR5/SRI/RASA3/C3AR1/CCL13/TMEM64/P2RX1/NMUR2/DISC1/ANXA6/BCL2/CCL8/TGM2/BAX/ATP1B1/MS4A1/CHRNA10/CCR6/PRKACA/LPAR3/GPR18/CXCR6/CCR4/CYBA/MICU1/LPAR1/MCOLN2/ATP13A5/PROK2/F2R/GRIN2C/CALR/SLC35G1/CAMK2D/PLCB1/CCR3/CEMIP/CXCR2/ABL2/NMB/CAV3/ATP2A2/HSP90B1/ANXA2P2/LETM1/SLC8A2/GIPR/TACR1/PSEN1/GNA13/GPR35/GALR1/P2RY4/HCRTR1/YWHAE/SYPL2/CASQ1/PLA2G6/SLC24A4/CAPN3/CASQ2/HRC/BDKRB1/GPR12/PKHD1/CD4/TMEM38B/LACRT/PIK3CG/CACNB3/OPRL1/ANXA2/LIME1/P2RY10/TRPV4/C5AR2/APP/GPR6/SNCA/CX3CL1/IAPP/CXCR3/P2RX2/SLC24A2/CIB2/CCL19/CCKBR/BAK1/CHERP/GCM2/ATP1A2/CCR7/SLC8A3/MCOLN3/FAM155A/GJA1/ACKR2/GPR20/ADCYAP1R1/CCRL2/CD24/KEL/P2RY1/NTSR1/MICU2/GHRL/KISS1/PIK3CB/P2RX5/SYNPO/GTF2I	193
BP	GO:0007266	Rho protein signal transduction	90/7096	203/18670	0.03721	0.1432	0.1067	RTN4R/CDC42EP4/RAC2/STMN1/CDC42SE1/ARHGEF18/RHOBTB1/PLEKHG2/SPATA13/MYO9B/BCL6/RHOC/ARHGEF3/FLOT1/ALS2/P2RY8/FGD6/FGD5/AKAP13/ARHGDIA/APOE/ARHGEF10L/RND3/ARHGEF40/CDC42EP2/ARRB1/KCTD10/HEG1/RHOG/CDC42SE2/ITSN1/ABR/NET1/ARHGDIB/ABL1/ARHGEF6/OPHN1/ABCA1/CTNNAL1/RHOT2/ARHGEF2/RAF1/RAC1/LPAR6/KALRN/CDC42EP3/FLCN/RHOU/ARHGAP6/BCR/SCAI/NRP1/RHOQ/CFL1/KANK1/GPR18/RHOV/OBSCN/RHOF/ITGA3/LPAR1/F2R/RHOH/RASGRF1/VAV1/ABL2/PREX1/ITSN2/GNA13/GPR35/APOA1/ARHGEF37/FGD3/RHOBTB3/ARHGEF17/PHACTR4/SYNPO2L/FGD4/EPS8L2/P2RY10/RHOA/MET/CHUK/ARHGEF4/WAS/ROCK2/RHOBTB2/GPR20/MCF2L/ARHGEF9	90
BP	GO:0045665	negative regulation of neuron differentiation	99/7096	225/18670	0.03723	0.1432	0.1067	RTN4R/DPYSL3/DLL1/ARF6/DNM3/WNT5A/DENND5A/TSC1/HMG20A/SEMA4B/VIM/LRIG2/SPP1/CIB1/ULK2/YWHAH/CERS2/EPHB2/ARHGDIA/IFRD1/APOE/GSK3B/PTPRO/NOTCH3/MIB1/UBE3A/DGUOK/RAPGEF2/BCL11A/SEMA4A/DTX1/CDK5/PLK2/TRAK2/PAFAH1B1/CTSZ/CDK5RAP2/SRGAP2C/GDI1/SEMA4C/PAQR3/SEMA4D/LRP1/HEY1/BMP7/RAB29/LRRK2/DCC/ASPM/PTK2/DIXDC1/SEMA6B/HDAC2/NRP1/SEMA3B/ID2/CTDSP1/CNTN4/KANK1/LGALS1/SYNGAP1/DAB1/INPP5F/RTN4RL1/SEMA5A/LPAR1/HES1/FSTL4/CALR/CNTF/TLX3/SLIT2/PSEN1/MDM2/SEMA5B/RTN4RL2/EIF4E/RUFY3/PLXNA3/SPOCK1/NR2F1/CARM1/MEIS1/EIF2AK4/NR2E1/MAP4K4/RHOA/TRPV4/APP/RTN4/BAG5/KREMEN1/ASAP1/LMX1A/FGF13/LRP4/EIF4ENIF1/FOXO3/TRIM46	99
BP	GO:0032715	negative regulation of interleukin-6 production	27/7096	53/18670	0.03729	0.1432	0.1067	KLF2/PTPN6/IL27RA/CSK/SYT11/TNFAIP3/BANK1/NLRP12/TNF/IRAK3/SLAMF1/HGF/ARRB1/SOCS5/TLR4/PTPN22/CD200R1/RABGEF1/HAVCR2/NLRX1/C5AR2/CX3CL1/NR1H4/NLRC3/C1QTNF3/GHRL/MIR146A	27
BP	GO:0045851	pH reduction	27/7096	53/18670	0.03729	0.1432	0.1067	ATP6V0D2/GRN/SLC11A1/ATP6AP1/DMXL1/ATP6V1C1/ATP6V0C/AQP11/TCIRG1/CLCN3/ATP6V1A/CLN3/RAB20/ATP6V1G3/ATP6V1B2/RAB38/ATP6V1D/ROGDI/BCL2/ATP6V0E2/CLN6/CLN5/ATP6V1G2/ATP6V1B1/CCKBR/SLAMF8/DMXL2	27
BP	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	27/7096	53/18670	0.03729	0.1432	0.1067	PTPN6/SOCS3/PPP2CA/PTPN2/PTPRC/CBLB/SOCS5/ZFYVE28/PRKCD/ZGPAT/HYAL2/MVP/PTK6/SEMA4D/SH3BP5L/SPINK1/SNX6/TSG101/CD300A/INPP5F/DMTN/VPS25/PSEN1/SOCS1/FGFR1OP/PRKCZ/MIR146A	27
BP	GO:1902475	L-alpha-amino acid transmembrane transport	27/7096	53/18670	0.03729	0.1432	0.1067	SLC43A2/RGS2/SLC38A7/PER2/SLC7A11/CLN8/SLC7A7/ARL6IP1/SLC7A6/PRAF2/SLC7A5/SLC43A1/SLC25A15/SLC38A1/SLC7A1/SLC25A12/SLC6A5/SLC7A8/SLC36A4/SLC25A13/PSEN1/SLC7A2/SLC25A22/SLC25A38/ATP1A2/SLC38A9/NTSR1	27
BP	GO:0030307	positive regulation of cell growth	76/7096	169/18670	0.03737	0.1434	0.1069	IGF1/S100A9/S100A8/FN1/TRIM32/ADNP2/RAB11A/RPS6KA3/CIB1/SLC9A1/PLAA/CXCL12/TWF2/PAK1/MEGF8/PTK2B/SRF/PARP2/VEGFA/TNFRSF12A/SFN/KLHL22/PAFAH1B1/GDI1/SDCBP/SEMA4D/LRP1/CDKN2AIP/EIF4G2/CYFIP1/DNPH1/DDX3X/SPHK1/NRP1/DISC1/BCL2/KDM2B/EXOSC2/L1CAM/LPAR3/IST1/NDEL1/CYBA/SEMA5A/MMP14/DERL2/EGFR/MUL1/SLC25A33/ADAM17/ITSN2/HAMP/SUPV3L1/TAF9B/EIF4G1/RASAL1/MAP3K13/RUFY3/EXOSC9/FGFR1OP/SYT1/CPNE9/PIN1/HBEGF/MAP2K5/SYT2/SYT4/MTOR/HPN/RHOA/CRABP2/RIMS2/MACF1/PRSS2/TRPV2/BMPR2	76
BP	GO:0007080	mitotic metaphase plate congression	23/7096	44/18670	0.03778	0.1445	0.1077	NUP62/RAB11A/SPDL1/CHMP4B/PSRC1/SEH1L/CENPE/MIS12/CDC23/CENPC/CHAMP1/NDC80/CHMP2A/NUF2/ZW10/CHMP1A/VPS4B/KIF2C/KPNB1/CHMP1B/RRS1/KIF14/BOD1	23
BP	GO:0050654	chondroitin sulfate proteoglycan metabolic process	23/7096	44/18670	0.03778	0.1445	0.1077	HEXB/VCAN/CHSY1/IDS/IMPAD1/HEXA/CHST13/ARSB/CSGALNACT1/CSPG4/CYTL1/XYLT1/CHST11/SLC35D1/B3GALT6/IDUA/XYLT2/CSGALNACT2/SPOCK2/BCAN/CHST12/B3GAT3/CHST7	23
BP	GO:0051489	regulation of filopodium assembly	23/7096	44/18670	0.03778	0.1445	0.1077	DPYSL3/ARF6/DNM3/ARAP1/PRKCD/SRF/SRGAP2C/PPP1R16B/TRPM2/NRP1/BCAS3/RHOQ/RAB5A/DMTN/DOCK11/FSCN1/FMR1/MYO10/TGFB3/MIEN1/CCR7/TENM2/ZMYND8	23
BP	GO:0071622	regulation of granulocyte chemotaxis	23/7096	44/18670	0.03778	0.1445	0.1077	RAC2/BST1/CAMK1D/CD74/MPP1/CMKLR1/CCL5/RAC1/C3AR1/MOSPD2/C1QBP/CXCR2/JAM3/SLIT2/LBP/TRPV4/C5AR2/DAPK2/CCL19/TIRAP/CCR7/IL23A/S100A14	23
BP	GO:1903573	negative regulation of response to endoplasmic reticulum stress	23/7096	44/18670	0.03778	0.1445	0.1077	TMBIM6/PPP1R15A/SGTA/WFS1/HSPA5/NCK1/UBE2J1/CLU/PPP1R15B/UBE2G2/LRRK2/TXNDC12/CREB3/PDX1/DNAJB9/DERL2/YOD1/BFAR/UBXN1/HYOU1/ERLEC1/OS9/ATF6B	23
BP	GO:0032259	methylation	156/7096	366/18670	0.03797	0.1448	0.1079	FOS/TRMT6/SPI1/LMNA/TPMT/PHF19/MEPCE/SMYD4/FTSJ1/CHTOP/AHCY/MTR/MYC/KDM1B/DPY30/FAM98B/SETDB2/ZNF304/EZH2/PAF1/WDR5B/HNMT/METTL14/VCPKMT/BTG2/DOT1L/TRMT5/TRMT1/SUV39H2/TET2/SETD4/COQ5/PRMT9/PRDM10/METTL25/TYW3/METTL18/METTL3/MBD1/NDUFAF7/NSD1/PIWIL4/TFB1M/MBD3/BCDIN3D/SETMAR/SETD5/DPH5/PPM1D/MTRR/LCMT2/TRMT112/GSTO1/FAM98A/PRDM4/SNRPB/COQ3/TRMT61B/NSUN2/SIRT1/MOV10L1/SETD9/METTL21A/SETD7/TRMT1L/PAXBP1/SMYD3/METTL22/BCOR/ASMTL/CBLL1/LCMT1/FBL/METTL7B/KMT2E/NTMT1/BTG1/SUV39H1/CYP1A2/ASH1L/METTL1/DNMT3L/SETD6/METTL8/HSD17B10/FTSJ3/CTCF/BHMT/FDXACB1/SETDB1/ETF1/AS3MT/GAMT/DIMT1/TYMS/CMTR1/ZCCHC4/WDR4/ALKBH8/THUMPD2/PRMT5/COPRS/ZMPSTE24/KDM4D/TRMT11/RNF20/TGS1/PWP1/METTL15/BRCA1/DNMT3A/METTL23/THUMPD3/AMT/PCMTD2/ICMT/MRM1/PRDM2/PRDM6/OGT/RAB3B/RLF/FBLL1/NSUN5P1/MEN1/PCMTD1/CARM1/CMTR2/KMT2B/MTO1/PRDM15/LRTOMT/PICK1/RAB3D/PAX7/PAX5/TRMT10C/GTPBP3/GCG/MGMT/EZH1/MTA2/PAXIP1/PRMT1/NSUN6/WDR82/NR1H4/MAT1A/WT1/COMTD1/WDR5/GRHL2/TET1/CIAPIN1/PRDM11/ZNF335	156
BP	GO:0046718	viral entry into host cell	56/7096	121/18670	0.03804	0.1448	0.1079	CLEC5A/CD55/WWP1/ITGA5/ITGB7/FCN1/ITGB5/TNFRSF14/F11R/SCARB1/IFITM2/LAMP1/IFITM1/CD74/IFITM3/SLAMF1/DPP4/AXL/XPR1/NCAM1/PTX3/HYAL2/TRIM26/CD209/LDLR/CTSB/TRIM11/CR1/CCR5/SELPLG/TRIM21/VPS18/PVR/LGALS1/ITGA2/CR2/SLC10A1/LGALS9/HYAL3/GPR15/EGFR/WWP2/MID2/TFRC/SLC20A2/SIVA1/TNFRSF4/CD4/CD80/TYRO3/DAG1/CDHR3/HAVCR1/MOG/APCS/CLDN6	56
BP	GO:0034104	negative regulation of tissue remodeling	12/7096	20/18670	0.03806	0.1448	0.1079	CSK/TNFAIP3/P2RX7/CST3/ABR/AGER/IL6/BCR/CLDN18/IAPP/TMEM119/GREM1	12
BP	GO:0034143	regulation of toll-like receptor 4 signaling pathway	12/7096	20/18670	0.03806	0.1448	0.1079	APPL2/LYN/TNFAIP3/LILRA2/PTPN22/MFHAS1/NR1H3/WDFY1/RAB7B/LBP/TIRAP/APPL1	12
BP	GO:0043369	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment	12/7096	20/18670	0.03806	0.1448	0.1079	STAT6/STAT3/LY9/BATF/IL6/CYLD/BCL2/IL12RB1/IL12B/TBX21/MTOR/IL23A	12
BP	GO:0050860	negative regulation of T cell receptor signaling pathway	12/7096	20/18670	0.03806	0.1448	0.1079	EZR/PTPN6/GBP1/PTPN2/DUSP3/LILRB4/PTPN22/ELF1/BTN2A2/UBASH3A/PTPRJ/PHPT1	12
BP	GO:0051767	nitric-oxide synthase biosynthetic process	12/7096	20/18670	0.03806	0.1448	0.1079	NOD2/TLR2/NAMPT/STAT1/JAK2/GSTP1/TLR4/PGGT1B/LRRK2/FCER2/MAP2K4/IFNG	12
BP	GO:0051769	regulation of nitric-oxide synthase biosynthetic process	12/7096	20/18670	0.03806	0.1448	0.1079	NOD2/TLR2/NAMPT/STAT1/JAK2/GSTP1/TLR4/PGGT1B/LRRK2/FCER2/MAP2K4/IFNG	12
BP	GO:0070932	histone H3 deacetylation	12/7096	20/18670	0.03806	0.1448	0.1079	PER2/SIRT7/HDAC11/SMARCAD1/SIRT1/SFPQ/HDAC2/HDAC7/HDAC4/ELK4/HDAC5/ATXN3L	12
BP	GO:1900017	positive regulation of cytokine production involved in inflammatory response	12/7096	20/18670	0.03806	0.1448	0.1079	MYD88/NOD2/CLEC7A/IL17RA/GBP5/TICAM1/TLR4/GPSM3/IL17B/APPL1/TLR6/IL17RC	12
BP	GO:0071478	cellular response to radiation	85/7096	191/18670	0.03811	0.1449	0.108	CRIP1/BMF/NAMPT/CDKN1A/NMT2/RAD51AP1/PTGS2/GNB1/MYC/EGR1/ERCC4/ATF4/RAD1/TGFB1/MAPK13/METTL3/USP28/RUVBL2/ZBTB1/HYAL2/TMEM161A/DDB1/INTS7/TMEM109/NET1/HSPA5/HRAS/NPM1/XRCC5/METAP2/PDE6G/SIRT1/EIF2S1/RHNO1/ATM/TNKS1BP1/POLH/ACTR5/DNM2/PCNA/NEDD4/BAX/NOC2L/ERCC1/YY1/CDC25A/OPN3/SWI5/TSPYL5/GRB2/CYBA/ST20/HYAL3/LIG4/ZMPSTE24/KDM4D/SDE2/FBXO4/IMPACT/C9orf116/E2F4/ATR/CLOCK/FMR1/HAMP/MDM2/DDB2/GUCY2D/POLD1/XRCC6/RBL2/RAD9A/CUL4B/GRK4/GPR52/EIF2AK4/TRIAP1/BAK1/MGMT/RGR/NUCKS1/SPIDR/RP1/OPN4/FIGNL1	85
BP	GO:0071897	DNA biosynthetic process	87/7096	196/18670	0.03875	0.1472	0.1097	KLF4/DUSP1/CDKN2D/CDKN1A/MAD2L2/CHRAC1/MYC/RGCC/MAP3K4/HGF/PTK2B/RPA1/PKIB/ZBTB1/NAF1/HNRNPA1/UBE2L6/HNRNPA2B1/POLD4/WRNIP1/DNAJC2/TEP1/DSCC1/XRCC5/TK1/DCP2/POLD2/ISG15/SIRT1/PDGFB/POLI/NAT10/RFC3/PTGES3/ATM/TNKS1BP1/POLH/MAPKAPK5/SPHK1/PARM1/NPLOC4/POLG/NHP2/HNRNPC/XRN1/PRKD2/PCNA/PARP3/LIN9/GAR1/UBC/TYMS/KCNK2/HNRNPD/LIG4/CCT4/DTL/FBXO4/POLL/CCT8/USP10/ATR/TK2/MAPK1/TELO2/ACD/CTC1/POLD1/GNL3L/HSP90AB1/MEN1/POLA1/POLA2/TERT/LIG3/POLB/VCP/PRKCQ/POT1/POLE4/NOP10/GJA1/GREM1/PNKP/NEK7/GRHL2/BMPR2	87
BP	GO:0002717	positive regulation of natural killer cell mediated immunity	18/7096	33/18670	0.03927	0.1487	0.1108	LAMP1/CD226/HLA-F/HLA-E/RASGRP1/HLA-G/PVR/LAG3/ULBP2/CRTAM/VAV1/KIR2DL4/AP1G1/NCR3/IL12B/SH2D1A/MICA/IL18RAP	18
BP	GO:0002756	MyD88-independent toll-like receptor signaling pathway	18/7096	33/18670	0.03927	0.1487	0.1108	IRF7/BIRC2/LY96/TICAM1/UBE2D3/IKBKG/TLR4/TRAF3/UBE2D2/CASP8/CD300LF/BIRC3/TNIP3/UBC/FADD/TLR3/CHUK/TLR6	18
BP	GO:0006891	intra-Golgi vesicle-mediated transport	18/7096	33/18670	0.03927	0.1487	0.1108	COG8/COPE/RAB33B/GOSR2/GOSR1/NAPA/COPG2/GOLGA5/COPA/VTI1A/COG6/NAPG/TRAPPC3/VTI1B/COG2/COG1/COPZ2/GOLGA3	18
BP	GO:0016242	negative regulation of macroautophagy	18/7096	33/18670	0.03927	0.1487	0.1108	PINK1/TSC1/RNF41/FEZ2/SEC22B/HMOX1/NUPR1/CHMP4B/HTRA2/QSOX1/LRRK2/PHF23/USP30/SMCR8/SCFD1/CLEC16A/MTOR/LZTS1	18
BP	GO:0045191	regulation of isotype switching	18/7096	33/18670	0.03927	0.1487	0.1108	IL27RA/MAD2L2/STAT6/BCL6/CD40/PTPRC/TGFB1/MLH1/PARP3/CLCF1/TFRC/TNFSF4/EXOSC3/TBX21/APLF/EXOSC6/PAXIP1/ATAD5	18
BP	GO:0070536	protein K63-linked deubiquitination	18/7096	33/18670	0.03927	0.1487	0.1108	TNFAIP3/UIMC1/ZRANB1/SPATA2/OTUD1/CYLD/OTUD4/SHMT2/USP16/OTUD5/DESI2/STAMBPL1/USP27X/ATXN3/YOD1/STAMBP/VCP/BRCC3	18
BP	GO:0045921	positive regulation of exocytosis	42/7096	88/18670	0.03935	0.1488	0.1109	ITGAM/STAM/RAB9A/ATP6AP1/IL4R/STXBP5/LAMP1/STXBP1/UNC13B/PTAFR/HLA-F/FGR/CDK5/SDCBP/DOC2B/ARF1/ADORA2B/CHMP2A/TSG101/UNC13D/RAB5A/SYTL4/HGS/HYAL3/VPS4B/DNM1L/CDK5R2/CLASP2/AP1G1/RAB3A/SYT9/PLA2G6/IFNG/SYT1/SNX4/SYT4/CADPS2/SCAMP5/RAB3D/SNCA/CACNA1H/RAB27A	42
BP	GO:0070098	chemokine-mediated signaling pathway	42/7096	88/18670	0.03935	0.1488	0.1109	CCR2/CX3CR1/OXSR1/CIB1/PPBP/ACKR3/CXCL9/CXCL11/CXCL10/CXCL12/HIF1A/PTK2B/CXCL13/CMKLR1/CCL5/RNF113A/CCL7/CXCR1/CCR5/CCL13/CCL8/CCR6/CXCR6/CCR4/CCR3/CXCR2/CCL20/SLIT2/CCL26/GPR35/TREM2/CX3CL1/CXCR3/CCL19/CCL4/CCR7/CCL24/ACKR2/CCRL2/CXCL6/THPO/SLIT3	42
BP	GO:0015807	L-amino acid transport	33/7096	67/18670	0.0394	0.1488	0.1109	SLC43A2/SLC11A1/SLC36A1/RGS2/SLC38A7/PER2/SLC7A11/CLN8/SLC7A7/ARL6IP1/SLC7A6/PRAF2/SLC7A5/SLC1A4/SLC43A1/SLC25A15/SLC38A1/SLC7A1/SLC25A12/SLC6A5/SLC7A8/SFXN1/SLC36A4/SLC25A13/PSEN1/SLC7A2/SLC25A22/SLC25A38/ATP1A2/SLC38A5/CTNS/SLC38A9/NTSR1	33
BP	GO:2000573	positive regulation of DNA biosynthetic process	33/7096	67/18670	0.0394	0.1488	0.1109	KLF4/MYC/RGCC/MAP3K4/HGF/PTK2B/PKIB/NAF1/HNRNPA1/HNRNPA2B1/DSCC1/XRCC5/PDGFB/RFC3/PTGES3/ATM/MAPKAPK5/PARM1/PRKD2/HNRNPD/CCT4/FBXO4/CCT8/ATR/MAPK1/ACD/HSP90AB1/PRKCQ/POT1/GREM1/PNKP/NEK7/GRHL2	33
BP	GO:0061008	hepaticobiliary system development	63/7096	138/18670	0.03947	0.1488	0.1109	ANXA1/ARF6/SRSF5/SRD5A1/HMGCL/TNFAIP3/LSR/DBP/CEBPG/FBXW7/CEBPB/HFE/EZH2/HMOX1/PKD2/KRAS/PKM/RELA/CSNK2A2/TGFB1/AACS/HMGCS1/HGF/PCK2/CEBPA/IGF2R/RAP1A/QDPR/CSNK2B/CCND1/MESP1/GNPNAT1/CITED2/SULF2/PCNA/MPST/ASNS/ITGA2/TYMS/PDX1/RHBDD3/HNRNPD/MKS1/PRMT5/HES1/ZMPSTE24/ADA/HLX/EGFR/WNT1/HAMP/FPGS/HNF1B/CAD/HNF1A/ATP7A/WDR35/HPN/AURKA/MET/PNPT1/PTCH1/E2F8	63
BP	GO:0006310	DNA recombination	126/7096	292/18670	0.03959	0.1488	0.1109	USP51/IL27RA/ZFYVE26/MAD2L2/STAT6/EID3/RAD51AP1/BCL6/MCM6/CD40/CCNB1IP1/MCM2/HUS1B/NABP1/PTPRC/UBE2N/BATF/KLHL15/ERCC4/MAGEF1/ALYREF/ACTR2/PPP4C/IL7R/PPP4R2/REC8/TGFB1/SMC5/RNF138/TSN/UNG/SMC6/RPA1/SWAP70/RUVBL2/RUVBL1/RMI2/RAD51B/CCDC155/TEP1/PALB2/NSMCE2/XRCC5/SAMHD1/HMGB1/SMCHD1/SMARCAD1/SFPQ/UCHL5/AP5S1/INO80C/RHNO1/TFPT/MCRS1/ATM/SETX/XRCC4/HDAC10/ACTR5/RAD52/MLH1/XRCC1/PARP3/HMGB2/ERCC1/FUS/RFWD3/YY1/CLCF1/CCR6/RMI1/TOP2B/RAD54B/SWI5/GEN1/MND1/TIMELESS/RECQL/LIG4/KDM4D/POLL/BRCA1/GINS4/BCL11B/TFRC/SYCE3/TNFSF4/MCM5/FANCM/RTEL1/SUPV3L1/KPNA1/ERCC2/EXO1/XRCC6/DCLRE1C/EXOSC3/SWSAP1/INO80D/TEX15/LIG3/POLB/PSMC3IP/TBX21/ANKRD31/MCM8/ZSWIM7/APLF/EXOSC6/AUNIP/WAS/PAXIP1/ATAD5/ACTL6A/UBE2B/ENDOG/CNTD1/TONSL/HMGB4/NUCKS1/SPIDR/FEN1/RECQL4/ZRANB3/TOP2A/FIGNL1	126
BP	GO:0007045	cell-substrate adherens junction assembly	39/7096	81/18670	0.03966	0.1488	0.1109	S100A10/TSC1/TRIP6/LDB1/SLC9A1/DUSP3/PEAK1/PTK2B/ACTN1/VEGFA/ABL1/TESK2/LRP1/PPM1F/SLK/RAC1/PTK2/ARHGAP6/BCR/LIMCH1/NRP1/BCL2/WDPCP/BCAS3/ITGA2/MMP14/DMTN/CORO1C/CLASP2/RCC2/HRG/MAP4K4/RHOA/LIMS1/ITGB1BP1/ROCK2/MACF1/PTPRJ/FMN1	39
BP	GO:0034109	homotypic cell-cell adhesion	39/7096	81/18670	0.03966	0.1488	0.1109	PTPN6/CLIC1/MYL12A/LYN/FLNA/VCL/SLC7A11/ACTB/TLN1/RDX/STXBP1/HSPB1/PRKCD/HBB/TSPAN32/CD99/FIBP/RAP2B/CCL5/P2RY12/MYH9/CTNNA3/CD99L2/ZNF703/LGALS1/PLEK/DMTN/BLOC1S4/DSC2/MEGF10/PKP2/PIK3CG/MEGF11/STXBP3/CSRP1/PRKCQ/TYRO3/PRKCA/PIK3CB	39
BP	GO:0048041	focal adhesion assembly	39/7096	81/18670	0.03966	0.1488	0.1109	S100A10/TSC1/TRIP6/LDB1/SLC9A1/DUSP3/PEAK1/PTK2B/ACTN1/VEGFA/ABL1/TESK2/LRP1/PPM1F/SLK/RAC1/PTK2/ARHGAP6/BCR/LIMCH1/NRP1/BCL2/WDPCP/BCAS3/ITGA2/MMP14/DMTN/CORO1C/CLASP2/RCC2/HRG/MAP4K4/RHOA/LIMS1/ITGB1BP1/ROCK2/MACF1/PTPRJ/FMN1	39
BP	GO:0031468	nuclear envelope reassembly	11/7096	18/18670	0.03969	0.1488	0.1109	PPP2CA/LMNA/CHMP4B/UBXN2B/EMD/NSFL1C/ANKLE2/BANF1/CHMP2A/VRK1/REEP3	11
BP	GO:0032693	negative regulation of interleukin-10 production	11/7096	18/18670	0.03969	0.1488	0.1109	DLL1/TNFRSF21/LILRB1/IDO1/AGER/TYROBP/PDCD1LG2/TRIB2/CD274/IL12B/IL23A	11
BP	GO:0045780	positive regulation of bone resorption	11/7096	18/18670	0.03969	0.1488	0.1109	ATP6AP1/SPP1/ADAM8/LTBP3/TNFRSF11A/PLEKHM1/TMEM64/EGFR/TFRC/DCSTAMP/PRKCA	11
BP	GO:0046852	positive regulation of bone remodeling	11/7096	18/18670	0.03969	0.1488	0.1109	ATP6AP1/SPP1/ADAM8/LTBP3/TNFRSF11A/PLEKHM1/TMEM64/EGFR/TFRC/DCSTAMP/PRKCA	11
BP	GO:1902165	regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	11/7096	18/18670	0.03969	0.1488	0.1109	MIF/CD44/CD74/HNRNPK/SIRT1/ELL3/MUC1/BCL2/TAF9B/TRIAP1/ATAD5	11
BP	GO:1903019	negative regulation of glycoprotein metabolic process	11/7096	18/18670	0.03969	0.1488	0.1109	AGO2/CST3/ITM2B/PTX3/ITM2A/BACE2/AATF/ABCA7/HBEGF/APCS/ACOT8	11
BP	GO:1900076	regulation of cellular response to insulin stimulus	36/7096	74/18670	0.0397	0.1488	0.1109	APPL2/SOCS3/TSC1/PTPN2/CCND3/ADIPOR1/CISH/GKAP1/RELA/CDK4/PAK1/ENHO/LEP/PRKCD/ZBTB7B/NCK1/IL1B/SIK2/SIRT1/MYO1C/GRB10/GNAI2/INPP5K/GPR21/KANK1/SERPINA12/PRKAA1/PID1/SOCS1/OGT/SLA2/PRKCZ/PRKCQ/SOCS2/NUCKS1/NR1H4	36
BP	GO:1901616	organic hydroxy compound catabolic process	36/7096	74/18670	0.0397	0.1488	0.1109	CYP27A1/GK/SCARB1/AKR1C3/INPP1/APOE/FAH/TPI1/SYNJ1/MAOA/ALDH2/SYNJ2/OCRL/NUDT3/GK5/INPP5K/IMPA2/MTMR2/SORD/AKR1B10/SRD5A3/MAOB/CYP27B1/SULT1B1/DBH/LRTOMT/CYP4F3/DIO2/CYP46A1/FGF23/ADH7/NTSR1/HAO1/SNX17/INPP5A/IMPA1	36
BP	GO:0010959	regulation of metal ion transport	167/7096	394/18670	0.04009	0.1495	0.1115	SLC8A1/FYN/KCNMB1/PTPN6/LILRB2/ATP2B4/LYN/OXSR1/KCNAB2/ATP1A1/DIAPH1/TMBIM6/KLHL24/PTGS2/LILRA5/CHP1/FLNA/NETO2/ACTN4/SIK1/YWHAH/LILRA2/CXCL9/CXCL11/P2RX7/HFE/SLC31A2/SLC9A1/CXCL10/FXYD5/TESC/PKD2/FXYD6/LILRB1/CXCL12/ATF4/TGFB1/KCNE3/KCNIP2/WFS1/ISCU/PTK2B/MYO5A/CD63/CORO1A/P2RY6/SCN1B/AHNAK/SARAF/PDE4B/ABL1/STIM2/GSTO1/HOMER3/CCL5/PLCG2/PML/P2RY12/DMD/HOMER1/ATP1B2/TMC2/PDGFB/G6PD/IL16/SPINK1/SUMO1/PSEN2/SRI/ATP1B3/MIR34A/ARF1/P2RX1/LRRC52/BCL2/FXYD1/DNM2/GNAI2/NEDD4/BAX/INPP5K/ATP1B1/PRKACA/LPAR3/KCNAB1/ADRB2/FHL1/RANGRF/KCNQ1/CYBA/CAMK2A/F2R/SCN2B/COMMD1/MYLK/CAMK2D/DPP6/AHCYL1/CEMIP/WWP2/ORAI1/AMIGO1/CAV3/ANXA2P2/STAC2/FMR1/HAMP/NKAIN4/FXYD7/GPR35/YWHAE/EPB41/CASQ1/TREM2/PLA2G6/CD84/CAPN3/CASQ2/HRC/IFNG/PKP2/EFHB/KCNIP1/VIP/ATP7A/FXYD2/KCNS2/KIF5B/BDKRB1/OPRD1/CD4/EHD3/TMEM38B/LACRT/PIK3CG/CACNB3/REM2/SNTA1/CD33/OPRL1/ANXA2/LIME1/RHOA/SNCA/CX3CL1/P2RX2/SLN/SLC30A10/BAK1/FXYD3/GCG/CCL4/TMC1/KCNE2/ATP1A2/GJA1/ADCYAP1R1/TRPV3/KEL/BIN1/CNTN1/TRPV2/NTSR1/PACSIN3/WNK2/CAMK2B/P2RX5	167
BP	GO:0048285	organelle fission	189/7096	449/18670	0.04012	0.1495	0.1115	IGF1/KLHDC8B/DUSP1/PEX11A/PINK1/MAD2L2/WNT5A/TMEM135/NUP62/RAB11A/FLNA/DYNC1LI1/CCNB1IP1/RGCC/GDAP1/PEX11G/SPIRE1/SPDL1/RAN/ERCC4/ACTR2/LRP5/CHMP4B/SLC2A8/PSRC1/MX2/REC8/KIF3B/RAD1/TGFB1/MEI1/SYCP3/SMC5/MIEF1/FIS1/UBE2S/SEH1L/PDS5A/INSR/CENPE/DDHD1/NAA10/UBXN2B/KLHL22/RAD51B/CDK5RAP2/CCDC155/SIRT7/IL1B/DSCC1/NSMCE2/TOM1L1/NSFL1C/CDKN1C/PHIP/KIF4A/PSMD13/SPAG5/TOM1L2/BMP7/MIS12/MOV10L1/KIF2A/CTDP1/PDGFB/LRRK2/PPARGC1A/CDC23/RCC1/ESPL1/ASPM/ZNF207/CENPC/LCMT1/SMC2/ATM/MTFR1L/ANAPC5/CHAMP1/NCAPD3/BUB3/SPHK1/PHF23/AKAP8/SPICE1/BCCIP/USP16/CCNE1/NDC80/MLH1/DNMT3L/PPP2R2D/BMP4/CHMP2A/SLC25A46/CYP26B1/CDKN1B/KIF20B/MX1/MAD2L1BP/RMI1/TOP2B/RAD54B/DSN1/IL1A/NDEL1/NUF2/PEX19/GEN1/M1AP/NUSAP1/MND1/INCENP/ZW10/CHMP1A/VPS4B/UBE2C/PRMT5/CENPK/DNM1L/ACTR3/CALR/MOS/TUBG2/NFE2L1/CDC26/PLCB1/CLASP2/STAG3/MUL1/PEX11B/SYCE3/RIOK2/CCNA1/FANCM/DLGAP5/KIF2C/BRDT/SMC3/INF2/KATNB1/RPL24/ANAPC4/MTBP/DIS3L2/RNF212B/MKI67/CDC27/CDC20/FANCD2/MASTL/PIN1/PCID2/RB1/STAG1/TEX15/MSX1/DPEP3/PSMC3IP/CUL9/MISP/ANKRD31/AURKAIP1/RHOA/AURKA/ANAPC11/FANCA/IK/KPNB1/MSTO1/CHMP1B/MTFR2/UBE2B/CNTD1/CCDC8/RRS1/MTFP1/CEP85/KIF14/BOD1/HORMAD1/AAAS/PRC1/TOP2A/WRAP73/FIGNL1/SEC16B/ACOT8/L3MBTL1	189
BP	GO:0001954	positive regulation of cell-matrix adhesion	26/7096	51/18670	0.04012	0.1495	0.1115	S100A10/TSC1/CIB1/GSK3B/CD36/PTK2B/NINJ1/VEGFA/ABL1/PPM1F/RAC1/EMP2/NRP1/DISC1/SKAP1/HRG/PRKCZ/MAP4K4/LIMS1/DAG1/CX3CL1/ITGB1BP1/CCR7/CD3E/PTPRJ/FMN1	26
BP	GO:0006213	pyrimidine nucleoside metabolic process	26/7096	51/18670	0.04012	0.1495	0.1115	TYMP/UPP1/AK3/NT5C/CDADC1/CTPS2/DPYD/CMPK1/TK1/APOBEC3G/APOBEC3C/NME3/APOBEC2/NME4/NME1/DCK/UCK1/TK2/APOBEC3B/CTPS1/CAD/CDA/UCKL1/NT5C3A/NT5M/UPP2	26
BP	GO:0051496	positive regulation of stress fiber assembly	26/7096	51/18670	0.04012	0.1495	0.1115	S100A10/FHOD1/TSC1/SORBS3/RHOC/RGCC/ARHGEF10L/EVL/PAK1/ABL1/PPM1F/RAC1/LIMCH1/NRP1/TPM1/CD47/LPAR1/PXN/APOA1/TGFB3/SYNPO2L/MTOR/RHOA/ITGB1BP1/ROCK2/SERPINF2	26
BP	GO:0072523	purine-containing compound catabolic process	26/7096	51/18670	0.04012	0.1495	0.1115	PNP/AHCY/ACOT7/HDDC3/NUDT1/NT5C/PDE4B/DPYD/HINT1/SAMHD1/NUDT9/MLYCD/DNPH1/NUDT3/PDE7A/ADA/NUDT7/GPX1/PDE8A/ENPP4/AMPD3/ABCD1/ADAL/NUDT16/AOX1/PDE8B	26
BP	GO:0032392	DNA geometric change	55/7096	119/18670	0.04059	0.1495	0.1115	ANXA1/ASCC3/MCM6/GINS1/MCM2/MTERF1/RAD23B/CHD1/ERCC6/RPA1/CHD2/RUVBL2/RUVBL1/DDB1/HNRNPA2B1/PURA/WRNIP1/DSCC1/XRCC5/HMGA1/CHD9/DHX9/GTF2F2/HMGB1/SMARCAD1/SMARCA1/RFC3/DDX3X/SETX/GTF2H4/ACTR5/CHD6/HMGB2/RAD54B/DDX1/UBC/RECQL/ERCC6L/GINS4/CETN2/MCM5/RTEL1/DDB2/SUPV3L1/ERCC2/XRCC6/CUL4B/NAV2/MCM8/POT1/RBX1/RECQL4/ZRANB3/TOP2A/ERCC8	55
BP	GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	22/7096	42/18670	0.04061	0.1495	0.1115	DIS3L/ANGEL1/ISG20/ISG20L2/XRN2/TOE1/DCP2/USB1/DCPS/XRN1/REXO2/EXOSC2/EXOSC7/CNOT7/ERI3/DIS3L2/EXOSC9/EXOSC3/EXOSC6/PNPT1/EXOSC8/EXOSC5	22
BP	GO:0018209	peptidyl-serine modification	138/7096	322/18670	0.04072	0.1495	0.1115	ATP2B4/MAPK12/PINK1/MAD2L2/WNT5A/SH2D3C/PTGS2/SMAD7/RPS6KA3/MIF/CSNK1G2/CD44/DYRK4/TNF/PRKACB/STK38L/VRK2/ERCC6/GSK3B/STK32C/MAPKAPK3/DYRK2/HCLS1/CSNK2A2/TGFB1/HGF/ARRB1/PAK1/MAPK7/CSNK1D/PRKCD/MAPK13/LATS1/DYRK1B/NSD1/POGLUT1/NAA10/PARP2/NCK1/VEGFA/CDK5/PLK2/PAK2/NLK/MAP3K12/PAQR3/ARAF/MARK1/DMD/RAF1/PPM1F/CREBL2/TTBK1/IL6/PDGFB/LRRK2/SMYD3/ATM/TNKS1BP1/CSNK1A1/BCAR3/CSNK1E/MAPKAPK5/FNIP1/NTMT1/MARK3/DCLK2/MAPK8/PLCL1/BCL2/PRKD2/MAPKAPK2/BAX/INPP5K/MARK2/PRKACA/TLK1/MAP4K1/CSNK1G3/IFNK/OSM/MAP2K2/SPOCK2/INPP5F/DDIT4/HIPK1/MGAT5B/CAMK2A/DMTN/PWP1/DYRK3/CAMK2D/ULK1/EGFR/TXN/PKN2/ATR/SPRY2/PRKAA1/MAPK1/VRK1/EIF4G1/CLSPN/MKNK2/MAP3K13/LMTK2/PLCL2/HRC/IFNG/HIPK3/LATS2/RET/MASTL/OPRD1/MAPKAP1/HSP90AB1/STK32B/TRIM6/PRKCZ/MTOR/PRKCQ/CLK1/AURKA/APP/ERN1/SNCA/TTBK2/GALNT1/TOP1/PDCD10/BAK1/CHUK/GCG/ROCK2/CSNK1G1/PRKCA/NTRK2/MAPK9	138
BP	GO:0046887	positive regulation of hormone secretion	60/7096	131/18670	0.04077	0.1495	0.1115	RETN/SPP1/PPARD/JAK2/HFE/PPP3CB/AACS/ARRB1/HIF1A/LEP/MCU/AIMP1/ITSN1/C2CD2L/MPC2/LRP1/CREB1/TRPM4/DOC2B/RAC1/GLUD1/IRS2/SERP1/SRI/OXCT1/RPH3AL/GPR27/INHBA/PDX1/TM7SF3/PFKFB2/RAB8B/EGFR/NMB/GIPR/GALR1/TCF7L2/BAD/PLA2G6/VIP/KIF5B/INHA/SNX4/GHRH/SOX4/GCG/NLGN2/GJA1/NR1H4/TARDBP/UCN3/RBP4/PSMD9/C1QTNF3/P2RY1/TACR2/GHRL/KISS1/APLN/PHPT1	60
BP	GO:0002295	T-helper cell lineage commitment	10/7096	16/18670	0.04106	0.1495	0.1115	STAT6/STAT3/LY9/BATF/IL6/IL12RB1/IL12B/TBX21/MTOR/IL23A	10
BP	GO:0002643	regulation of tolerance induction	10/7096	16/18670	0.04106	0.1495	0.1115	LILRB2/IRAK3/CLC/IDO1/HMGB1/HLA-G/CD274/HAVCR2/CD3E/PDCD1	10
BP	GO:0002830	positive regulation of type 2 immune response	10/7096	16/18670	0.04106	0.1495	0.1115	NOD2/NLRP3/IL4R/CD74/RSAD2/IDO1/IL6/IL18/TNFSF4/PRKCZ	10
BP	GO:0010885	regulation of cholesterol storage	10/7096	16/18670	0.04106	0.1495	0.1115	PPARD/SCARB1/CD36/NR1H2/ABCA1/EHD1/ABCG1/NR1H3/SREBF2/PPARA	10
BP	GO:0032354	response to follicle-stimulating hormone	10/7096	16/18670	0.04106	0.1495	0.1115	GCLM/POR/SRD5A1/HMGCS1/GCLC/PPARGC1A/EPHA8/ASNS/INHBA/FSHR	10
BP	GO:0033631	cell-cell adhesion mediated by integrin	10/7096	16/18670	0.04106	0.1495	0.1115	ITGA5/DPP4/SWAP70/CXCL13/ITGA4/CCL5/ADA/ADAM9/SKAP1/CD3E	10
BP	GO:0034975	protein folding in endoplasmic reticulum	10/7096	16/18670	0.04106	0.1495	0.1115	EMC3/EMC2/PDIA3/HSPA5/DNAJC10/CANX/SUCO/CALR/HSP90B1/EMC1	10
BP	GO:0043981	histone H4-K5 acetylation	10/7096	16/18670	0.04106	0.1495	0.1115	JADE3/KAT7/KAT8/MCRS1/PHF20/KANSL1L/OGT/ING4/JADE1/WDR5	10
BP	GO:0043982	histone H4-K8 acetylation	10/7096	16/18670	0.04106	0.1495	0.1115	JADE3/KAT7/KAT8/MCRS1/PHF20/KANSL1L/OGT/ING4/JADE1/WDR5	10
BP	GO:0045722	positive regulation of gluconeogenesis	10/7096	16/18670	0.04106	0.1495	0.1115	PTPN2/KAT2B/DDB1/SIRT1/DGAT2/PPARGC1A/PPARA/KAT2A/GCG/WDR5	10
BP	GO:0048012	hepatocyte growth factor receptor signaling pathway	10/7096	16/18670	0.04106	0.1495	0.1115	STMN1/PTPN2/HGF/PAK1/RAC1/ADAMTS12/NRP1/MST1/HPN/MET	10
BP	GO:0051382	kinetochore assembly	10/7096	16/18670	0.04106	0.1495	0.1115	SENP6/CENPW/CENPE/CENPT/CENPN/MIS12/CENPC/CENPK/CENPA/RNF4	10
BP	GO:0060628	regulation of ER to Golgi vesicle-mediated transport	10/7096	16/18670	0.04106	0.1495	0.1115	RNF139/SAR1B/LRRK2/SAR1A/ARF1/TBC1D20/STX18/INSIG1/SCFD1/PREB	10
BP	GO:1902004	positive regulation of amyloid-beta formation	10/7096	16/18670	0.04106	0.1495	0.1115	TNF/CASP3/CLU/ABCG1/IFNGR1/IFNG/APP/GSAP/PICALM/ROCK2	10
BP	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	10/7096	16/18670	0.04106	0.1495	0.1115	MIF/CD44/CD74/SIRT1/ELL3/MUC1/BCL2/TAF9B/TRIAP1/ATAD5	10
BP	GO:0000012	single strand break repair	7/7096	10/18670	0.04133	0.1495	0.1115	APTX/SIRT1/XRCC1/LOC100133315/LIG4/TDP1/APLF	7
BP	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	7/7096	10/18670	0.04133	0.1495	0.1115	APBB1IP/FGL2/LILRB1/ITGAL/HLA-DMB/LGALS9/HAVCR2	7
BP	GO:0003376	sphingosine-1-phosphate receptor signaling pathway	7/7096	10/18670	0.04133	0.1495	0.1115	EZR/S1PR4/S1PR3/S1PR1/SPHK1/GPR6/S1PR5	7
BP	GO:0007084	mitotic nuclear envelope reassembly	7/7096	10/18670	0.04133	0.1495	0.1115	PPP2CA/LMNA/EMD/ANKLE2/BANF1/VRK1/REEP3	7
BP	GO:0007220	Notch receptor processing	7/7096	10/18670	0.04133	0.1495	0.1115	APH1B/PSENEN/PSEN2/ADAM17/PSEN1/DNER/APH1A	7
BP	GO:0010998	regulation of translational initiation by eIF2 alpha phosphorylation	7/7096	10/18670	0.04133	0.1495	0.1115	NCK1/NPM1/PPP1R15B/IMPACT/EIF2AK2/EIF2AK1/EIF2AK4	7
BP	GO:0030388	fructose 1,6-bisphosphate metabolic process	7/7096	10/18670	0.04133	0.1495	0.1115	FBP1/PFKM/PFKP/ALDOC/ALDOA/IFNG/PFKL	7
BP	GO:0030647	aminoglycoside antibiotic metabolic process	7/7096	10/18670	0.04133	0.1495	0.1115	CBR4/AKR1B1/AKR1C3/AKR7A2/AKR1A1/AKR1C1/AKR1B10	7
BP	GO:0032070	regulation of deoxyribonuclease activity	7/7096	10/18670	0.04133	0.1495	0.1115	PRKCD/NPM1/DFFA/GZMA/HMGB1/SIRT1/PCNA	7
BP	GO:0032621	interleukin-18 production	7/7096	10/18670	0.04133	0.1495	0.1115	TLR2/NLRP3/NLRP12/GBP5/DHX9/NLRP9/CD84	7
BP	GO:0034135	regulation of toll-like receptor 2 signaling pathway	7/7096	10/18670	0.04133	0.1495	0.1115	TLR1/LYN/TNFAIP3/MFHAS1/CYBA/TIRAP/TLR6	7
BP	GO:0035376	sterol import	7/7096	10/18670	0.04133	0.1495	0.1115	STARD4/SCARB1/CD36/LAMTOR1/LDLR/LRP1/APOA1	7
BP	GO:0036500	ATF6-mediated unfolded protein response	7/7096	10/18670	0.04133	0.1495	0.1115	WFS1/HSPA5/CALR/HSP90B1/MBTPS2/MBTPS1/ATF6B	7
BP	GO:0042048	olfactory behavior	7/7096	10/18670	0.04133	0.1495	0.1115	WFS1/ADCY3/GJB4/UBR3/SHANK1/ATP6V1B1/LMX1A	7
BP	GO:0043379	memory T cell differentiation	7/7096	10/18670	0.04133	0.1495	0.1115	TSC1/BCL6/FGL2/IL12RB1/TNFSF4/IL12B/IL23A	7
BP	GO:0044359	modulation of molecular function in other organism	7/7096	10/18670	0.04133	0.1495	0.1115	RAB9A/PTX3/CASP8/ANXA2P2/ANXA2/NUCKS1/APCS	7
BP	GO:0045625	regulation of T-helper 1 cell differentiation	7/7096	10/18670	0.04133	0.1495	0.1115	ANXA1/IL4R/SOCS5/HLX/TNFSF4/CD80/CCL19	7
BP	GO:0045792	negative regulation of cell size	7/7096	10/18670	0.04133	0.1495	0.1115	TSC1/RDX/AKT1S1/CAV3/DEPTOR/MTOR/RHOA	7
BP	GO:0046498	S-adenosylhomocysteine metabolic process	7/7096	10/18670	0.04133	0.1495	0.1115	AHCY/APIP/MTRR/ENOPH1/GAMT/AHCYL2/AHCYL1	7
BP	GO:0048021	regulation of melanin biosynthetic process	7/7096	10/18670	0.04133	0.1495	0.1115	WNT5A/SLC7A11/ZEB2/RAPGEF2/ASIP/CDH3/APPL1	7
BP	GO:0052205	modulation of molecular function in other organism involved in symbiotic interaction	7/7096	10/18670	0.04133	0.1495	0.1115	RAB9A/PTX3/CASP8/ANXA2P2/ANXA2/NUCKS1/APCS	7
BP	GO:0060068	vagina development	7/7096	10/18670	0.04133	0.1495	0.1115	WNT5A/AXL/BAX/MERTK/TYRO3/BAK1/RBP4	7
BP	GO:0070391	response to lipoteichoic acid	7/7096	10/18670	0.04133	0.1495	0.1115	TLR2/RELA/CD36/TLR4/TREM2/LBP/TIRAP	7
BP	GO:0070508	cholesterol import	7/7096	10/18670	0.04133	0.1495	0.1115	STARD4/SCARB1/CD36/LAMTOR1/LDLR/LRP1/APOA1	7
BP	GO:0070862	negative regulation of protein exit from endoplasmic reticulum	7/7096	10/18670	0.04133	0.1495	0.1115	UBE2J1/UBE2G2/DERL2/INSIG1/YOD1/ERLEC1/OS9	7
BP	GO:0071223	cellular response to lipoteichoic acid	7/7096	10/18670	0.04133	0.1495	0.1115	TLR2/RELA/CD36/TLR4/TREM2/LBP/TIRAP	7
BP	GO:0071670	smooth muscle cell chemotaxis	7/7096	10/18670	0.04133	0.1495	0.1115	GSTP1/AIF1/CORO1B/MIR34A/LPAR1/SLIT2/PDGFD	7
BP	GO:0090715	immunological memory formation process	7/7096	10/18670	0.04133	0.1495	0.1115	TSC1/BCL6/FGL2/IL12RB1/TNFSF4/IL12B/IL23A	7
BP	GO:0097050	type B pancreatic cell apoptotic process	7/7096	10/18670	0.04133	0.1495	0.1115	WFS1/CAST/EIF2S1/IL6/SRSF6/PDX1/TCF7L2	7
BP	GO:0106049	regulation of cellular response to osmotic stress	7/7096	10/18670	0.04133	0.1495	0.1115	PTGS2/ARHGEF2/EFHD1/MICU1/YBX3/LETM1/BAD	7
BP	GO:0110096	cellular response to aldehyde	7/7096	10/18670	0.04133	0.1495	0.1115	AIFM1/AKR1B1/ADH5/ESD/AKR1A1/RDH12/AKR1B10	7
BP	GO:0150011	regulation of neuron projection arborization	7/7096	10/18670	0.04133	0.1495	0.1115	WNT5A/DVL2/MOV10/GRIP1/FZD4/DVL1/MAP3K13	7
BP	GO:1900222	negative regulation of amyloid-beta clearance	7/7096	10/18670	0.04133	0.1495	0.1115	TNF/HMGCR/LRPAP1/SRF/MIR34A/IFNGR1/IFNG	7
BP	GO:1902101	positive regulation of metaphase/anaphase transition of cell cycle	7/7096	10/18670	0.04133	0.1495	0.1115	NSMCE2/ESPL1/ANAPC5/DLGAP5/ANAPC4/RB1/ANAPC11	7
BP	GO:1903332	regulation of protein folding	7/7096	10/18670	0.04133	0.1495	0.1115	GRN/PDCL/SGTA/HSPA5/PDCD5/BAG5/ST13	7
BP	GO:1903862	positive regulation of oxidative phosphorylation	7/7096	10/18670	0.04133	0.1495	0.1115	PINK1/PGK1/NUPR1/ISCU/MYOG/PGK2/VCP	7
BP	GO:2000665	regulation of interleukin-13 secretion	7/7096	10/18670	0.04133	0.1495	0.1115	ARG2/IL17RA/LILRA5/TNFRSF21/LGALS9/PRKCZ/IL17RB	7
BP	GO:0051480	regulation of cytosolic calcium ion concentration	152/7096	357/18670	0.04152	0.1496	0.1115	SLC8A1/FPR2/HTR2B/FPR1/CCR2/FYN/CX3CR1/PTGER4/PTPN6/S1PR4/ATP2B4/LYN/CD55/WNT5A/MCOLN1/S1PR3/PTGER2/TPCN1/DIAPH1/TMBIM6/GNB1/S1PR1/GNA15/ACKR3/P2RY8/CXCL9/JAK2/CXCL11/PTPRC/P2RX7/BCAP31/CXCL10/PKD2/TGFB1/ITPR1/FIS1/CD36/LPAR2/PTK2B/MYO5A/SWAP70/CORO1A/P2RY6/CXCL13/RYR1/FZD9/CDK5/ABL1/CMKLR1/GSTO1/CLN3/PLCG2/PML/CYSLTR1/LRP1/HMGB1/DMD/TRPM4/NPTN/TRPM2/LPAR6/CXCR1/LCK/CCR5/SRI/RASA3/C3AR1/TMEM64/P2RX1/NMUR2/BCL2/TGM2/BAX/MS4A1/CHRNA10/CCR6/PRKACA/LPAR3/GPR18/CXCR6/CCR4/CYBA/LPAR1/MCOLN2/PROK2/F2R/GRIN2C/SLC35G1/CAMK2D/PLCB1/CCR3/CEMIP/CXCR2/ABL2/NMB/CAV3/ANXA2P2/LETM1/GIPR/TACR1/GNA13/GPR35/GALR1/P2RY4/HCRTR1/YWHAE/CASQ1/PLA2G6/CAPN3/CASQ2/HRC/BDKRB1/CD4/TMEM38B/LACRT/PIK3CG/CACNB3/OPRL1/ANXA2/LIME1/P2RY10/TRPV4/C5AR2/GPR6/SNCA/CX3CL1/IAPP/CXCR3/P2RX2/CIB2/CCL19/CCKBR/BAK1/CHERP/ATP1A2/CCR7/SLC8A3/MCOLN3/FAM155A/GJA1/ACKR2/GPR20/ADCYAP1R1/CCRL2/CD24/P2RY1/NTSR1/GHRL/KISS1/P2RX5/SYNPO/GTF2I	152
BP	GO:0014065	phosphatidylinositol 3-kinase signaling	67/7096	148/18670	0.04171	0.1496	0.1115	KLF4/IGF1/HTR2B/FYN/PTPN6/LYN/FLT1/PPARD/PLEKHA1/PRR5/JAK2/TNF/GAB1/PTPN13/HCLS1/UBE3A/IER3/HGF/LEP/INSR/PIK3IP1/NCF1/FLT3/PDGFC/EPOR/FGR/IGF1R/CAT/CCL5/RASGRP1/PIK3R6/SEMA4D/SIRT1/PPP1R16B/IRS2/PDGFB/PPP2R5C/PTK2/CEP55/NYAP1/NEDD4/PIK3CD/OSM/UNC5B/PDGFA/BTN2A2/F2R/SERPINA12/C1QBP/EGFR/IL18/MAPK1/STAMBP/FBXL2/MAZ/FSHR/PPP2R5B/PIK3CG/RELN/PIP5K1B/LIME1/TYRO3/NLRC3/ERBB3/PDGFD/NTRK2/PIK3CB	67
BP	GO:0002523	leukocyte migration involved in inflammatory response	9/7096	14/18670	0.042	0.1496	0.1115	S100A9/S100A8/ADAM8/FFAR2/CCR6/JAM3/LBP/CX3CL1/SLAMF8	9
BP	GO:0002834	regulation of response to tumor cell	9/7096	14/18670	0.042	0.1496	0.1115	CD226/FBXO38/HMGB1/PVR/CD274/CRTAM/HAVCR2/HRG/IL12B	9
BP	GO:0002837	regulation of immune response to tumor cell	9/7096	14/18670	0.042	0.1496	0.1115	CD226/FBXO38/HMGB1/PVR/CD274/CRTAM/HAVCR2/HRG/IL12B	9
BP	GO:0006244	pyrimidine nucleotide catabolic process	9/7096	14/18670	0.042	0.1496	0.1115	NEIL2/UNG/NT5C/TDG/DCTPP1/NT5M/DUT/MBD4/SMUG1	9
BP	GO:0006684	sphingomyelin metabolic process	9/7096	14/18670	0.042	0.1496	0.1115	SGMS2/PRKCD/SPTLC2/SAMD8/CLN3/ENPP7/SGMS1/SMPD1/SMPD2	9
BP	GO:0019081	viral translation	9/7096	14/18670	0.042	0.1496	0.1115	EIF2D/DHX9/EIF3G/MCTS1/EIF3B/PCBP2/SSB/EIF2AK4/EIF3L	9
BP	GO:0020027	hemoglobin metabolic process	9/7096	14/18670	0.042	0.1496	0.1115	KLF4/LDB1/HIF1A/CAT/INHBA/EIF2AK1/EPB42/INHA/PRMT1	9
BP	GO:0032688	negative regulation of interferon-beta production	9/7096	14/18670	0.042	0.1496	0.1115	LILRB1/REL/NMI/CACTIN/RELB/YY1/NLRX1/TRAF3IP1/NLRC3	9
BP	GO:0044546	NLRP3 inflammasome complex assembly	9/7096	14/18670	0.042	0.1496	0.1115	NLRP3/GBP5/CD36/TLR4/MEFV/CPTP/EIF2AK2/NLRC3/TLR6	9
BP	GO:0046341	CDP-diacylglycerol metabolic process	9/7096	14/18670	0.042	0.1496	0.1115	CDS1/GPAM/CDS2/AGPAT3/CDIPT/AGPAT4/AGPAT5/AGPAT1/AGPAT2	9
BP	GO:0046855	inositol phosphate dephosphorylation	9/7096	14/18670	0.042	0.1496	0.1115	INPP1/SYNJ1/SYNJ2/OCRL/INPP5K/IMPA2/MTMR2/INPP5A/IMPA1	9
BP	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning	9/7096	14/18670	0.042	0.1496	0.1115	PRKACB/TULP3/WDR19/GORAB/PRKACA/MKS1/GPR161/TRAF3IP1/PTCH1	9
BP	GO:0070234	positive regulation of T cell apoptotic process	9/7096	14/18670	0.042	0.1496	0.1115	WNT5A/ADAM8/PRELID1/IDO1/NFKBID/CCL5/CD274/LGALS9/PDCD1	9
BP	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus	9/7096	14/18670	0.042	0.1496	0.1115	TSC1/RAN/EIF6/NPM1/ZNF593/NUP88/LTV1/RIOK2/RRS1	9
BP	GO:1903624	regulation of DNA catabolic process	9/7096	14/18670	0.042	0.1496	0.1115	AIFM1/NMNAT1/DFFA/IL6/ATM/BAX/ST20/ENDOG/MIR146A	9
BP	GO:1904152	regulation of retrograde protein transport, ER to cytosol	9/7096	14/18670	0.042	0.1496	0.1115	BCAP31/EDEM1/UBE2J1/UBE2G2/EDEM2/DERL2/YOD1/ERLEC1/OS9	9
BP	GO:0002082	regulation of oxidative phosphorylation	17/7096	31/18670	0.04205	0.1496	0.1115	PINK1/PGK1/NUPR1/ISCU/DNAJC30/UQCC2/COX7A2L/SHMT2/MYOG/PGK2/SLC25A33/DNAJC15/ATP7A/VCP/RHOA/SNCA/ABCD1	17
BP	GO:0006506	GPI anchor biosynthetic process	17/7096	31/18670	0.04205	0.1496	0.1115	PIGV/PIGP/PIGK/PIGN/PIGF/PIGB/DPM1/GPAA1/PIGM/MPPE1/PIGQ/PIGO/PIGH/DPM3/PIGT/PGAP3/PGAP1	17
BP	GO:1903393	positive regulation of adherens junction organization	17/7096	31/18670	0.04205	0.1496	0.1115	S100A10/ARF6/TSC1/DUSP3/VEGFA/ABL1/IQSEC1/PPM1F/RAC1/MAPRE2/NRP1/HRG/MAP4K4/LIMS1/ITGB1BP1/PTPRJ/FMN1	17
BP	GO:0048284	organelle fusion	57/7096	124/18670	0.04205	0.1496	0.1115	ANXA1/VAT1/STX7/STX11/GNAI3/TAP2/TAP1/SEC22B/SAMD9L/GDAP1/C2CD5/VPS41/STXBP1/FIS1/CORO1A/VAMP3/SAMD9/OMA1/RAB20/ANKRD27/BET1/RAB8A/DOC2B/AFG3L2/GOSR2/GOSR1/TAPBP/STX5/SPHK1/VPS18/BAX/STX16/USP30/NKD2/VTI1A/RAB7B/DNM1L/CALR/RAB8B/MUL1/ANXA2P2/RAB3A/PID1/STX12/VTI1B/SYT9/STX8/SYT1/KIF5B/VPS16/VAMP1/SNAP29/SYT4/ANXA2/SNCA/BAK1/VPS8	57
BP	GO:0034637	cellular carbohydrate biosynthetic process	41/7096	86/18670	0.04219	0.1496	0.1115	IGF1/FBP1/EXTL2/NDST2/AKR1B1/HS2ST1/B3GNT8/PER2/IMPAD1/EXT2/EXT1/GSK3B/AGL/DYRK2/B3GNT2/PCK2/LEP/PPP1R3E/INSR/GYS1/PPP1R3D/GYG2/CSGALNACT1/B3GNT5/IRS2/PHKG1/PGM2/INPP5K/IMPA2/PPP1R3B/NDST1/PPP1R3F/CSGALNACT2/B4GALT5/PPP1CA/B3GNT4/PPP1CB/ESRRB/MTOR/B4GALT1/IMPA1	41
BP	GO:0002371	dendritic cell cytokine production	8/7096	12/18670	0.04224	0.1496	0.1115	NOD2/DDX21/TICAM1/TLR4/DDX58/MAVS/DDX1/TLR3	8
BP	GO:0003334	keratinocyte development	8/7096	12/18670	0.04224	0.1496	0.1115	PSAP/SFN/CDSN/FLNB/BCL11B/DNASE1L2/FOSL2/IFT74	8
BP	GO:0010826	negative regulation of centrosome duplication	8/7096	12/18670	0.04224	0.1496	0.1115	KAT2B/TRIM37/NPM1/CDK5RAP2/CHMP2A/BRCA1/KAT2A/CCNF	8
BP	GO:0042368	vitamin D biosynthetic process	8/7096	12/18670	0.04224	0.1496	0.1115	VDR/CYP27A1/TNF/NFKB1/IL1B/CYP27B1/SNAI1/IFNG	8
BP	GO:0043476	pigment accumulation	8/7096	12/18670	0.04224	0.1496	0.1115	CD63/BLOC1S6/ANKRD27/RAB32/RAB38/BLOC1S3/AP1G1/AP1M1	8
BP	GO:0043482	cellular pigment accumulation	8/7096	12/18670	0.04224	0.1496	0.1115	CD63/BLOC1S6/ANKRD27/RAB32/RAB38/BLOC1S3/AP1G1/AP1M1	8
BP	GO:0051132	NK T cell activation	8/7096	12/18670	0.04224	0.1496	0.1115	ELF4/IL15/ZBTB7B/RASAL3/CD300A/IL18/IL12B/IL23A	8
BP	GO:0051549	positive regulation of keratinocyte migration	8/7096	12/18670	0.04224	0.1496	0.1115	ARF6/IQSEC1/MAPRE2/MMP9/ADAM9/HBEGF/MAP4K4/MTOR	8
BP	GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	8/7096	12/18670	0.04224	0.1496	0.1115	ZFP36/TOB1/AGO2/BTG2/TNRC6B/TNRC6A/CPEB3/CNOT7	8
BP	GO:0071679	commissural neuron axon guidance	8/7096	12/18670	0.04224	0.1496	0.1115	EPHB2/ROBO3/NCAM1/VEGFA/NRP1/DAG1/SMO/PTCH1	8
BP	GO:0072393	microtubule anchoring at microtubule organizing center	8/7096	12/18670	0.04224	0.1496	0.1115	NINL/PCM1/BICD2/BICD1/BBS4/HOOK3/CCDC120/CEP19	8
BP	GO:0072540	T-helper 17 cell lineage commitment	8/7096	12/18670	0.04224	0.1496	0.1115	STAT3/LY9/BATF/IL6/IL12RB1/IL12B/TBX21/IL23A	8
BP	GO:0090148	membrane fission	8/7096	12/18670	0.04224	0.1496	0.1115	CHMP4B/MX2/TMCC1/SLC25A46/MX1/CORO1C/DNM1L/SH3GLB1	8
BP	GO:1900165	negative regulation of interleukin-6 secretion	8/7096	12/18670	0.04224	0.1496	0.1115	IL27RA/SYT11/BANK1/PTPN22/CD200R1/RABGEF1/C5AR2/C1QTNF3	8
BP	GO:1902510	regulation of apoptotic DNA fragmentation	8/7096	12/18670	0.04224	0.1496	0.1115	AIFM1/NMNAT1/DFFA/IL6/BAX/ST20/ENDOG/MIR146A	8
BP	GO:1904424	regulation of GTP binding	8/7096	12/18670	0.04224	0.1496	0.1115	STMN1/C9orf72/CCPG1/EIF2S1/GPSM1/CSNK1A1/CLN5/MET	8
BP	GO:0009247	glycolipid biosynthetic process	32/7096	65/18670	0.04236	0.1497	0.1116	PIGV/PIGP/PIGK/SCCPDH/PIGN/B4GALT6/B3GNT5/ST3GAL2/PIGF/PIGB/DPM1/GPAA1/PIGM/MPPE1/B4GALNT1/PIGQ/GAL3ST4/B4GALT5/PIGO/UGCG/ST8SIA4/PIGH/ST6GALNAC5/PRKAA1/DPM3/PIGT/ST6GALNAC3/ST6GALNAC6/PGAP3/ST8SIA1/ST3GAL5/PGAP1	32
BP	GO:0045739	positive regulation of DNA repair	32/7096	65/18670	0.04236	0.1497	0.1116	MAD2L2/PARP9/EYA3/CEBPG/UBE2N/SPIRE1/ERCC6/ACTR2/UIMC1/TMEM161A/SETMAR/DHX9/HMGB1/SMCHD1/SIRT1/DTX3L/HDAC10/PCNA/XRCC1/PARP3/FUS/TIMELESS/KDM4D/BRCA1/EGFR/EYA4/BRCC3/MGMT/WAS/NUDT16/SPIDR/ERCC8	32
BP	GO:0071806	protein transmembrane transport	32/7096	65/18670	0.04236	0.1497	0.1116	TIMM23B/PEX12/C2CD5/PEX16/SEC62/SEC61B/MCL1/HSPA5/DNAJC19/TIMM17A/CLU/TIMM21/GRPEL1/RTN2/BCR/GRPEL2/BLOC1S3/TOMM22/TOMM40L/PEX13/TOMM40/TOMM20/TIMM22/PEX14/AGK/DNAJC15/SEC61G/TIMM50/SEC61A2/TRAM1/TIMM44/TIMM9	32
BP	GO:0042113	B cell activation	133/7096	310/18670	0.04238	0.1497	0.1116	NOD2/PTPN6/IL27RA/DLL1/CDKN1A/BST1/KLF6/LYN/MAD2L2/NOTCH2/RBPJ/TNIP2/MNDA/STAT6/PTPN2/BCL6/TNFAIP3/BANK1/CD40/MIF/CEBPG/LFNG/PTPRC/BATF/DOCK10/CD74/TNFRSF21/CD320/TICAM1/CD22/IL7R/ZBTB7A/TGFB1/LAT2/AKAP17A/POU2F2/UNG/PTK2B/TNFSF13B/SWAP70/PRKCD/ZBTB1/TCIRG1/ITGA4/TLR4/FLT3/FZD9/GON4L/CASP3/ABL1/SLC39A10/CASP8/PLCG2/ITM2A/AHR/TPD52/ICOSLG/IL7/TYROBP/BLNK/TRBC1/IL6/IRS2/CYLD/CTLA4/ATM/LYL1/FNIP1/FCRL1/MLH1/BCL2/PARP3/BAX/NFATC2/ERCC1/HDAC4/PIK3CD/ID2/MS4A1/CLCF1/CCR6/LGALS1/IFNK/CR2/PPP2R3C/INHBA/CD300A/LAX1/LIG4/MMP14/DNAJB9/ADA/CHRNA4/LRRC8A/ITFG2/ADAM17/DOCK11/CDH17/TFRC/TNFRSF13B/TNFSF4/NFAM1/CHRNB2/EXO1/BAD/ZFP36L2/TNFRSF4/DCLRE1C/IGBP1/CTPS1/PLCL2/EXOSC3/PCID2/INHA/GAPT/TNFRSF13C/SLA2/TBX21/HDAC5/APLF/GPR183/EXOSC6/IKZF3/MALT1/TIRAP/BAK1/PAXIP1/ATAD5/SKAP2/SLAMF8/IGHD/MEF2C/PTPRJ	133
BP	GO:0007051	spindle organization	76/7096	170/18670	0.04292	0.1515	0.113	EZR/SUN2/STMN1/NUP62/RAB11A/FLNA/SENP6/RAN/HAUS8/CHMP4B/PSRC1/KIF3B/CENPW/MAP4/CSNK1D/CENPE/PLK2/CCDC155/KIF4A/MAPRE1/SPAG5/MAPRE2/KIF2A/RCC1/ESPL1/ASPM/ZNF207/KIZ/MYH9/HAUS2/NTMT1/NCOR1/CCDC69/SPICE1/BCCIP/NDC80/MLH1/PARP3/CHMP2A/RGS14/TUBGCP3/CKAP5/DCTN2/NUF2/CHMP1A/VPS4B/MOS/CEP63/TUBG2/CLASP2/TUBGCP5/GPSM2/HAUS5/HAUS1/TUBB1/SMC3/SPC25/CDC20/RNF4/STAG1/TBCE/VCP/CEP120/MISP/RHOA/AURKA/AUNIP/KPNB1/EFHC1/MSTO1/SAC3D1/CHMP1B/NEK7/AAAS/PRC1/WRAP73	76
BP	GO:0034260	negative regulation of GTPase activity	25/7096	49/18670	0.04318	0.1523	0.1135	CDC42SE1/TSC1/F11R/IQGAP2/SH3BP4/RDX/ARRB1/ARFGEF1/HRAS/MKKS/GPSM1/LRRK2/PDE6D/BBS4/BCAS3/PTPRN2/SPRY1/RHOH/GMIP/RCC2/SLIT2/SPRY2/GPS1/CPEB2/FZD10	25
BP	GO:0045010	actin nucleation	25/7096	49/18670	0.04318	0.1523	0.1135	SPIRE1/IQGAP2/ACTR2/EVL/GMFG/CORO1A/ARPC1A/ARPIN/ARPC1B/CYFIP1/CORO1B/ARF1/ARPC5L/JMY/ACTR3B/ACTR3/LMOD3/SCIN/ARPC4/ARPC2/PICK1/WAS/NCKAP1/FCHSD2/FMN1	25
BP	GO:0097530	granulocyte migration	64/7096	141/18670	0.04321	0.1523	0.1135	S100A9/S100A8/S100A12/PTGER4/RAC2/ANXA1/BST1/IL17RA/CAMK1D/PPBP/CXCL9/CXCL11/ADAM8/CD74/CXCL10/MPP1/IRAK4/CXCL13/CD99/PDE4B/CMKLR1/IL1B/CCL5/CCL7/IL1RN/IL1R1/RAC1/CXCR1/CKLF/C3AR1/MOSPD2/CCL13/CD99L2/CCL8/PIK3CD/CD300A/MCOLN2/C1QBP/VAV1/CXCR2/CCL20/JAM3/PREX1/SLIT2/CCL26/CSF3R/PIK3CG/LBP/PRTN3/TRPV4/C5AR2/DAPK2/CX3CL1/CCL19/TIRAP/CCL4/CCR7/CCL24/SLAMF8/IL23A/IL17RC/CXCL6/S100A14/IL37	64
BP	GO:0042593	glucose homeostasis	105/7096	241/18670	0.04322	0.1523	0.1135	HK3/PDK4/TRA2B/APPL2/GCLM/STAT3/PTPN2/ADIPOR1/ENY2/CYB5R4/HMGCR/LRP5/PDK2/PPP3CB/SIN3A/AACS/UNC13B/FIS1/ARRB1/HIF1A/FFAR2/WFS1/PIM3/PCK2/LEP/SRF/INSR/MCU/CEBPA/IGF1R/GCLC/AGER/C2CD2L/RAP1A/MPC2/LRP1/CRTC2/RAF1/SIRT1/TRPM4/RAC1/IRS2/ZNF236/PPARGC1A/KLF7/MBD5/BACE2/SRI/OXCT1/POLG/RPH3AL/GPR27/INPP5K/GPR21/NME1/RMI1/PRKACA/LGALS1/SLC16A1/PDX1/FOXK2/CYBA/PTPRN2/FOXO4/HMGN3/FABP5/ASPSCR1/NMB/CAV3/CMA1/ADIPOR2/PRKAA1/TCF7L2/BAD/PLA2G6/HNF1A/KIF5B/SUCNR1/MEN1/DBH/WDR35/PYGL/STXBP3/ZBTB20/NDUFAF2/MAP4K4/TRPV4/ERN1/SLC9B2/SOX4/SIDT2/GCG/ENDOG/KLF15/NUCKS1/NR1H4/STXBP4/SESN2/RBP4/G6PC/PTCH1/FOXO3/GHRL/MIR146A/PHPT1	105
BP	GO:0002761	regulation of myeloid leukocyte differentiation	54/7096	117/18670	0.04332	0.1524	0.1136	FOS/SIGLEC15/LYN/IRF7/NOTCH2/ATP6AP1/PTPN2/KLF10/LILRB3/KITLG/FBXW7/MYC/CEBPB/TNF/CD74/TESC/LILRB1/HCLS1/TGFB1/ROR2/LILRB4/TRAF6/TLR4/CASP8/MITF/CREB1/TYROBP/TFE3/TAL1/TMEM64/ID2/NME1/INHBA/EVI2B/PIAS3/FADD/DCSTAMP/LRRC17/TREM2/C1QC/IFNG/CLDN18/CD4/RB1/TLR3/INHA/IL12B/MTOR/FOXP1/SLC9B2/HOXA7/PRKCA/IL23A/APCS	54
BP	GO:0007613	memory	54/7096	117/18670	0.04332	0.1524	0.1136	CX3CR1/ITGA5/NTAN1/PTGS2/LGMN/CEBPB/APOE/CIC/PPP3CB/SRF/INSR/PLK2/S100B/LDLR/CREB1/EIF4EBP2/KALRN/ARC/CRTC1/ADCY1/RGS14/SHANK1/KCNK2/CPEB3/ITGA3/NPAS4/RASGRF1/ABCA7/PLCB1/ATXN1L/SLC8A2/MAP1A/KAT2A/PSEN1/CHRNB2/PLA2G6/ITGA8/ATXN1/RIN1/DBH/EIF2AK4/SYT4/KMT2B/PRKCZ/RELN/MTOR/SLC24A2/LMX1A/FGF13/SLC8A3/CTNS/ATAD1/SHANK3/FEN1	54
BP	GO:0022904	respiratory electron transport chain	54/7096	117/18670	0.04332	0.1524	0.1136	PINK1/UQCRC2/UQCR11/NDUFA8/AIFM2/ETFA/NDUFC1/ISCU/NDUFB11/NDUFS3/NDUFA3/NDUFA11/ETFDH/UQCR10/COX7C/PPARGC1A/ALDH5A1/COX7A2L/NDUFA4/IMMP2L/SLC25A12/COX4I2/NDUFA1/MYBBP1A/ETFB/COQ9/COA6/COX15/NDUFA10/NDUFB1/NDUFB5/UQCRQ/NDUFS1/SLC25A13/NDUFB8/DNAJC15/NDUFB6/NDUFB3/SDHA/NDUFS7/NDUFAF2/NDUFV2/ND4/SDHD/TAZ/SNCA/UQCRB/SLC25A22/NDUFB2/SDHAF2/COX6C/NDUFS2/NDUFA7/COX7B	54
BP	GO:0009395	phospholipid catabolic process	21/7096	40/18670	0.04368	0.1535	0.1144	ENPP2/GDE1/ABHD6/ABHD12/GPCPD1/APOC1/SCARB1/PNPLA6/PRKCD/NAPEPLD/PLA2G15/PLCG2/LDLR/IDH1/PNPLA8/ENPP7/PRDX6/INPP5F/SMPD1/ABHD16A/SMPD2	21
BP	GO:0072583	clathrin-dependent endocytosis	21/7096	40/18670	0.04368	0.1535	0.1144	DLL1/SYT11/FCHO1/FCHO2/ITGA4/CLTB/DNAJC6/AP2A2/UBQLN2/GPR107/DNM2/KIAA1107/AP2S1/INPP5F/CANX/AP2A1/AP2M1/SLC9B2/PICALM/FCHSD2/PIK3CB	21
BP	GO:0048024	regulation of mRNA splicing, via spliceosome	46/7096	98/18670	0.04372	0.1535	0.1145	CELF6/TRA2B/NSRP1/JMJD6/SRSF5/KHDRBS1/DAZAP1/RNPS1/THRAP3/RBM7/ZBTB7A/RBM42/SRSF10/HNRNPK/MBNL1/YTHDC1/RBM4/RBM4B/HNRNPA1/HNRNPA2B1/RBM8A/SRPK2/SFSWAP/SRSF3/MBNL3/RBMXL1/RBM3/CWC22/SRSF6/PRDX6/SREK1/SRSF7/SF3B4/SRPK1/C1QBP/FMR1/CELF2/SRSF4/ZC3H10/RBM25/PRPF19/CELF3/HMX2/SRRM4/SAP18/SON	46
BP	GO:1901796	regulation of signal transduction by p53 class mediator	80/7096	180/18670	0.04449	0.1561	0.1164	BARD1/PMAIP1/MIF/CD44/CD74/DYRK2/HEXIM1/CSNK2A2/RAD1/EEF1E1/RPA1/PTTG1IP/HNRNPK/BANP/MBD3/RMI2/RBBP7/CDK5/TAF11/TAF12/PML/RBBP4/CSNK2B/SIRT1/SETD9/ELL3/TAF5/RHNO1/TP53RK/RFC3/ATM/MUC1/MAPKAPK5/HDAC2/PRKAG2/PLK3/TRIM24/KAT5/RAD17/BCL2/BRPF1/NOC2L/RMI1/RPF2/SSRP1/PHF20/JMY/RFFL/HIPK1/PRMT5/ZMPSTE24/SPRED1/DYRK3/BRCA1/ATR/RRM2B/PRKAA1/MDM2/TAF9B/EXO1/TAF4/SNAI1/RAD9A/PPP1R13B/TOPBP1/MAPK11/PRKAG1/PIN1/MSX1/SUPT16H/TBP/TRIAP1/AURKA/MTA2/ATAD5/RRS1/HIC1/TAF7/PRKAB1/L3MBTL1	80
BP	GO:0098739	import across plasma membrane	51/7096	110/18670	0.04455	0.1562	0.1165	SLC8A1/KCNJ5/KCNJ15/FYN/ATP2B4/SLC9A9/ATP1A1/RGS2/FOLR2/PER2/HFE/SLC7A11/SLC9A1/CLN8/ARL6IP1/ISCU/SLC39A10/ATP4A/SLC12A9/KCNJ1/SLC39A8/TRPM4/TRPM2/ATP1B2/SLC9A7/ATP1B3/SLC7A1/SLC12A2/HCN4/SLC12A8/SLC6A5/ATP1B1/KCNJ8/SLC46A1/SLC39A12/SLC36A4/PSEN1/IFNG/SLC7A2/FXYD2/SLC12A1/SLC12A7/SLC12A4/KCNE2/ATP1A2/SLC8A3/FAM155A/SLC9C2/ATP12A/NTSR1/SLC12A6	51
BP	GO:1902806	regulation of cell cycle G1/S phase transition	89/7096	202/18670	0.04462	0.1563	0.1166	KLF4/PTPN6/ATP2B4/ANXA1/CDKN2D/CDKN1A/GPNMB/CCND3/MEPCE/DDRGK1/ZNF655/FBXW7/RGCC/SLFN11/EZH2/LSM11/PAF1/PKD2/GIGYF2/PSME1/BTG2/CCND2/CDK4/RDX/CDKN2B/PLK2/SFN/AIF1/PML/CDK2AP2/CCND1/DDX3X/ATM/TNKS1BP1/MUC1/KMT2E/CTDSPL/PLK3/PSME3/NACC2/UBE2E2/CCNE1/BCL2/PCNA/BAX/ANKRD17/CRADD/ID2/CASP2/CTDSP1/RFWD3/CDKN1B/CDKN2C/CNOT4/FHL1/PLAGL1/ARID3A/BTN2A2/E2F4/PLCB1/EGFR/CNOT7/GML/ADAM17/CTDSP2/MDM2/EIF4G1/WEE1/RBL2/MTBP/DCUN1D3/CUL4B/TMEM14B/RB1/C10orf99/MEN1/CNOT10/CARM1/JADE1/TERT/TRIAP1/AURKA/CDC73/SOX4/PRMT1/STXBP4/KIF14/E2F8/SUSD2	89
BP	GO:0030260	entry into host cell	61/7096	134/18670	0.04474	0.1563	0.1166	CLEC5A/CD55/WWP1/ITGA5/ITGB7/FCN1/ITGB5/TNFRSF14/F11R/SCARB1/IFITM2/LAMP1/IFITM1/CD74/IFITM3/SLAMF1/DPP4/AXL/XPR1/NCAM1/PTX3/HYAL2/TRIM26/CD209/LDLR/CTSB/TRIM11/CR1/CCR5/CBLL1/SELPLG/TRIM21/VPS18/PVR/LGALS1/ITGA2/CR2/GRB2/SLC10A1/LGALS9/HYAL3/GPR15/EGFR/WWP2/MID2/TFRC/SLC20A2/SIVA1/TNFRSF4/FUCA2/CD4/CD80/TYRO3/DAG1/CDHR3/MET/HAVCR1/MOG/APCS/EXOC2/CLDN6	61
BP	GO:0044409	entry into host	61/7096	134/18670	0.04474	0.1563	0.1166	CLEC5A/CD55/WWP1/ITGA5/ITGB7/FCN1/ITGB5/TNFRSF14/F11R/SCARB1/IFITM2/LAMP1/IFITM1/CD74/IFITM3/SLAMF1/DPP4/AXL/XPR1/NCAM1/PTX3/HYAL2/TRIM26/CD209/LDLR/CTSB/TRIM11/CR1/CCR5/CBLL1/SELPLG/TRIM21/VPS18/PVR/LGALS1/ITGA2/CR2/GRB2/SLC10A1/LGALS9/HYAL3/GPR15/EGFR/WWP2/MID2/TFRC/SLC20A2/SIVA1/TNFRSF4/FUCA2/CD4/CD80/TYRO3/DAG1/CDHR3/MET/HAVCR1/MOG/APCS/EXOC2/CLDN6	61
BP	GO:0051806	entry into cell of other organism involved in symbiotic interaction	61/7096	134/18670	0.04474	0.1563	0.1166	CLEC5A/CD55/WWP1/ITGA5/ITGB7/FCN1/ITGB5/TNFRSF14/F11R/SCARB1/IFITM2/LAMP1/IFITM1/CD74/IFITM3/SLAMF1/DPP4/AXL/XPR1/NCAM1/PTX3/HYAL2/TRIM26/CD209/LDLR/CTSB/TRIM11/CR1/CCR5/CBLL1/SELPLG/TRIM21/VPS18/PVR/LGALS1/ITGA2/CR2/GRB2/SLC10A1/LGALS9/HYAL3/GPR15/EGFR/WWP2/MID2/TFRC/SLC20A2/SIVA1/TNFRSF4/FUCA2/CD4/CD80/TYRO3/DAG1/CDHR3/MET/HAVCR1/MOG/APCS/EXOC2/CLDN6	61
BP	GO:0051828	entry into other organism involved in symbiotic interaction	61/7096	134/18670	0.04474	0.1563	0.1166	CLEC5A/CD55/WWP1/ITGA5/ITGB7/FCN1/ITGB5/TNFRSF14/F11R/SCARB1/IFITM2/LAMP1/IFITM1/CD74/IFITM3/SLAMF1/DPP4/AXL/XPR1/NCAM1/PTX3/HYAL2/TRIM26/CD209/LDLR/CTSB/TRIM11/CR1/CCR5/CBLL1/SELPLG/TRIM21/VPS18/PVR/LGALS1/ITGA2/CR2/GRB2/SLC10A1/LGALS9/HYAL3/GPR15/EGFR/WWP2/MID2/TFRC/SLC20A2/SIVA1/TNFRSF4/FUCA2/CD4/CD80/TYRO3/DAG1/CDHR3/MET/HAVCR1/MOG/APCS/EXOC2/CLDN6	61
BP	GO:0002381	immunoglobulin production involved in immunoglobulin mediated immune response	28/7096	56/18670	0.04474	0.1563	0.1166	IL27RA/MAD2L2/STAT6/BCL6/CD40/FGL2/PTPRC/BATF/TGFB1/POU2F2/UNG/SWAP70/MLH1/PARP3/ERCC1/CLCF1/CCR6/LIG4/TFRC/TNFSF4/EXO1/EXOSC3/GAPT/TBX21/APLF/EXOSC6/PAXIP1/ATAD5	28
BP	GO:1905515	non-motile cilium assembly	28/7096	56/18670	0.04474	0.1563	0.1166	TTC8/IFT172/IFT57/BBS10/MAP4/PCM1/CSNK1D/ARL13B/IFT80/FUZ/INTU/BBS2/GORAB/MKKS/IFT52/BBS4/MAK/DISC1/DNM2/BBS7/MKS1/TMEM80/CCDC13/TMEM107/IFT74/RP1/C2CD3/WRAP73	28
BP	GO:0000132	establishment of mitotic spindle orientation	16/7096	29/18670	0.04501	0.1569	0.1169	SPDL1/UBXN2B/PAFAH1B1/CDK5RAP2/SAPCD2/NSFL1C/ARHGEF2/BCCIP/NDC80/NDEL1/ZW10/SPRY1/GPSM2/SPRY2/CENPA/MISP	16
BP	GO:0010575	positive regulation of vascular endothelial growth factor production	16/7096	29/18670	0.04501	0.1569	0.1169	PTGS2/ATF4/TGFB1/CYP1B1/HIF1A/IL1B/IL6ST/IL6/SULF2/C3AR1/HPSE/ADORA2B/IL1A/ARNT/BRCA1/RORA	16
BP	GO:0046134	pyrimidine nucleoside biosynthetic process	16/7096	29/18670	0.04501	0.1569	0.1169	TYMP/UPP1/CTPS2/CMPK1/TK1/NME3/NME4/NME1/DCK/UCK1/TK2/CTPS1/CAD/CDA/UCKL1/UPP2	16
BP	GO:0051642	centrosome localization	16/7096	29/18670	0.04501	0.1569	0.1169	EZR/SUN2/FHOD1/BICD2/PAFAH1B1/ASPM/SYNE2/NDEL1/GPSM2/IFT20/CEP83/KIF5B/PLXNA2/DYNC1LI2/MISP/AURKA	16
BP	GO:0055075	potassium ion homeostasis	16/7096	29/18670	0.04501	0.1569	0.1169	ATP1A1/ATP4A/SLC12A9/ATP1B2/ATP1B3/SLC12A2/SLC12A8/ATP1B1/SLC12A1/SLC12A7/KCNMA1/ATP6V1B1/SLC12A4/ATP1A2/ATP12A/SLC12A6	16
BP	GO:0048588	developmental cell growth	102/7096	234/18670	0.04514	0.1572	0.1172	IGF1/RTN4R/FN1/DPYSL2/WNT5A/C9orf72/SEMA4B/SPP1/RAB11A/ULK2/RGS2/LAMB2/ALCAM/VCL/AKAP13/IFRD1/APOE/GSK3B/ZEB2/PLAA/CXCL12/TWF2/PPP3CB/SIN3A/PAK1/MEGF8/BCL11A/SRF/SEMA4A/ITGA4/PARP2/VEGFA/USP9X/CDK5/TNFRSF12A/CYFIP2/ABL1/PAFAH1B1/GDI1/MEX3C/SEMA4C/SEMA4D/LRP1/CTDP1/DCC/G6PD/CYFIP1/SEMA6B/PDLIM5/PLXNA1/ARIH2/NRP1/DISC1/SEMA3B/DNM2/L1CAM/NRP2/YY1/LPAR3/IST1/NDEL1/OLFM1/WDR36/SEMA5A/FSTL4/IMPACT/ULK1/MUL1/PPARA/CAV3/ITSN2/SLIT2/DVL1/CPNE1/HAMP/SEMA5B/MAP2K4/POU4F3/RASAL1/MAP3K13/RUFY3/PLXNA3/SYT1/CPNE9/PIN1/HSP90AB1/SYT2/EIF2AK4/SYT4/PRKCZ/MTOR/AURKA/APP/RTN4/CRABP2/RIMS2/FGF13/MACF1/TRPV2/TRIM46/BMPR2/SLIT3	102
BP	GO:0048678	response to axon injury	37/7096	77/18670	0.04568	0.159	0.1186	KLF4/RTN4R/DPYSL3/GRN/LYN/SOD1/LRIG2/SPP1/MAP2K1/MTR/LAMB2/JAK2/CERS2/NREP/CTNNA1/ARF4/AIF1/P2RY12/LRP1/TYROBP/MIR34A/MORN4/BCL2/BAX/LGALS1/NDEL1/INPP5F/RTN4RL1/KCNK2/CNTF/DHFR/JAM3/GIPR/APOA1/RTN4RL2/DAG1/KREMEN1	37
BP	GO:0061515	myeloid cell development	34/7096	70/18670	0.04582	0.1594	0.1189	SIGLEC15/KLF2/TLR2/PTPN6/NOTCH2/JMJD6/ATP6AP1/LYAR/BCL6/FBXW7/LILRB1/TMOD3/FAM210B/ZBTB7A/SRF/PAFAH1B1/TYROBP/G6PD/TAL1/EVI2B/DMTN/ANXA2P2/ERCC2/SLC4A1/EPB42/CLDN18/MEIS1/ANXA2/FOXP1/APP/SLC9B2/TSPAN2/TRIM58/THPO	34
BP	GO:0045727	positive regulation of translation	58/7096	127/18670	0.04628	0.1609	0.1199	PINK1/VIM/PPP1R15A/TNF/KHDRBS1/YTHDF3/PAIP1/EIF6/CDK4/UQCC1/PTAFR/PTK2B/METTL3/CNBP/EIF2B5/HABP4/NCK1/NPM1/LARP4/GUF1/UQCC2/CCL5/DHX9/IL6/NAT10/DDX3X/SERP1/RBM3/RPS9/RXRA/USP16/TARBP2/PRR16/ITGA2/ZCCHC4/HNRNPD/CPEB3/YBX3/POLR2D/IMPACT/COA3/LARP4B/C1QBP/EIF5A/NGRN/FMR1/MAPK1/RPUSD3/RPS6KB2/JMJD4/EIF2AK4/MTOR/RHOA/SAMD4A/SOX4/TRMT10C/MPV17L2/BOLL	58
BP	GO:0050890	cognition	127/7096	296/18670	0.04629	0.1609	0.1199	CRHBP/NRGN/FOS/FYN/CX3CR1/TLR2/LILRB2/PRKAR2B/ITGA5/ATP8A1/NTAN1/THRA/PTGS2/GM2A/LGMN/TTC8/CEBPB/TNF/SLC7A11/EPHB2/KRAS/APOE/HMGCR/BTG2/ACTR2/CIC/PPP3CB/CLN8/RP9/HIF1A/ARF4/SYNJ1/SRF/INSR/FZD9/CDK5/PLK2/SLC1A4/CASP3/PAFAH1B1/GPR155/CLN3/S100B/AGER/LDLR/GATM/TIFAB/CREB1/NPTN/DGCR2/EIF4EBP2/TTBK1/EGR2/KALRN/HLA-DRA/CYFIP1/ARC/CRTC1/ADCY1/BBS4/CBR3/ADCY3/RGS14/MGAT3/JAKMIP1/KCNAB1/SYNGAP1/SHANK1/KCNK2/CPEB3/ITGA3/BHLHB9/NPAS4/VDAC1/RASGRF1/CHRNA4/ABCA7/GRPR/PLCB1/TUSC3/EGFR/C1QL1/METTL23/ATXN1L/SLC8A2/MAP1A/KAT2A/PSEN1/MAPK1/CHRNB2/IFT20/PLA2G6/ITGA8/FOSL1/VIP/ATXN1/RIN1/DBH/EIF2AK4/SYT4/KMT2B/PRKCZ/OPRL1/RELN/VDAC3/MTOR/BRSK1/APP/SHC3/SLC24A2/PTPRZ1/LMX1A/FGF13/ATP1A2/SLC8A3/PICALM/CTNS/ATAD1/SHANK3/FEN1/AAAS/TACR2/NTSR1/NTRK2/MEF2C/SYNPO/STRA6	127
BP	GO:0030574	collagen catabolic process	24/7096	47/18670	0.0465	0.1613	0.1203	CTSD/MRC2/CTSS/PHYKPL/CTSK/PEPD/CST3/ADAM15/FURIN/MMP12/CTSB/MMP9/ADAMTS2/MMP3/MMP1/MMP14/COL15A1/MMP2/PRTN3/MMP27/MMP10/MMP16/MMP19/PRSS2	24
BP	GO:0050435	amyloid-beta metabolic process	24/7096	47/18670	0.0465	0.1613	0.1203	IGF1/TNF/PSENEN/APOE/CASP3/TMED10/CLU/BACE2/PSEN2/ABCG1/MGAT3/ABCA7/IFNGR1/PSEN1/APEH/IFNG/PIN1/REN/APP/GSAP/APH1A/PICALM/ROCK2/BIN1	24
BP	GO:1901068	guanosine-containing compound metabolic process	24/7096	47/18670	0.0465	0.1613	0.1203	GNAI3/RAN/AK3/NFS1/MPP1/HDDC3/GMPS/DGUOK/RAB23/MBIP/GUK1/IMPDH1/MOCS2/LRRK2/NME3/NME4/GTPBP1/GMPR2/RHOQ/NME1/MOCS3/RHOA/AMPD3/GIMAP7	24
BP	GO:1990778	protein localization to cell periphery	133/7096	311/18670	0.04679	0.1621	0.1208	MYADM/S100A10/EZR/MPP5/STX7/PLS1/ARF6/RILPL1/CSK/GBP1/GGA2/ANKRD9/RAB11A/FLNA/FCHO2/CIB1/FLOT1/SQSTM1/F11R/DCHS1/VAMP5/TNF/C2CD5/EPHB2/SYS1/RAPGEF6/TESC/RAB31/ACTB/TGFB1/RDX/STXBP1/GRIPAP1/RAPGEF2/CLIP1/MYO5A/ARL13B/RHOG/TTC7A/GOPC/GORASP2/CDK5/VAMP3/HRAS/FAM126A/C16orf70/SAPCD2/GRIP1/NUMB/WDR19/CNST/RAP1A/LRP1/BBS2/RAB8A/RAB29/PREPL/SPTBN1/FLOT2/DENND4C/ATP1B3/PDZD11/EMP2/GOLPH3L/INPP5K/PACS2/ATP1B1/RHOQ/GRASP/TSPAN33/TMEM88/CNPY4/ADAM22/RANGRF/KIF13A/GPR158/NKD2/ARFRP1/ITGA3/MMP14/GRIN2C/TSPAN5/CLASP2/DPP6/RAB8B/RABEP1/EGFR/LIN7C/GPSM2/CAV3/IQSEC2/ANXA2P2/LRRC7/STAC2/RAB3A/PID1/IFT20/EPB41/VTI1B/PRAM1/SLC4A1/TREM2/SYTL2/KIF1B/IFNG/PKP2/SKAP1/STX8/KIF5B/EHD3/RAB3B/CACNB3/OPTN/EPB41L2/AP2M1/PRKCZ/GPC4/MISP/ANXA2/DAG1/RAB3D/CLIP3/ITGB1BP1/RER1/FGF13/PICALM/ROCK2/APPL1/RAB26/EFR3A/P2RY1/PTCH1/MACF1	133
BP	GO:0030516	regulation of axon extension	45/7096	96/18670	0.04679	0.1621	0.1208	RTN4R/FN1/DPYSL2/WNT5A/SEMA4B/RAB11A/IFRD1/APOE/GSK3B/CXCL12/TWF2/SIN3A/PAK1/MEGF8/SRF/SEMA4A/VEGFA/CDK5/TNFRSF12A/ABL1/PAFAH1B1/GDI1/SEMA4C/SEMA4D/LRP1/CYFIP1/SEMA6B/NRP1/DISC1/SEMA3B/DNM2/L1CAM/NDEL1/OLFM1/WDR36/SEMA5A/SEMA5B/MAP3K13/RUFY3/PLXNA3/RTN4/MACF1/TRPV2/TRIM46/BMPR2	45
BP	GO:0048010	vascular endothelial growth factor receptor signaling pathway	45/7096	96/18670	0.04679	0.1621	0.1208	MYOF/FYN/ITGA5/FLT1/VEGFB/MAPKAPK3/AXL/HIF1A/HSPB1/PTK2B/NCF4/NCF2/BAIAP2/NCF1/NCK1/VEGFA/CYFIP2/PAK2/IL1B/CRK/RAC1/CYFIP1/PTK2/GRB10/SHB/NRP1/PRKD2/MAPKAPK2/NEDD4/NRP2/HGS/CYBA/CYBB/ARNT/ELMO1/PXN/VAV1/FZD4/MAPK11/SH2D2A/RHOA/ROCK2/NCKAP1/ELMO2/PIK3CB	45
BP	GO:0006656	phosphatidylcholine biosynthetic process	20/7096	38/18670	0.04699	0.1623	0.121	SLC27A1/CDS1/CHPT1/CAPN2/CSNK2A2/STARD10/CSNK2B/STARD7/FABP3/ABHD3/RAB38/MFSD2A/LCAT/CHKA/FABP5/APOA1/SLC44A2/CHAT/LPCAT1/CHKB	20
BP	GO:0009225	nucleotide-sugar metabolic process	20/7096	38/18670	0.04699	0.1623	0.121	PGM3/EXTL2/GNPDA1/UAP1/NAGK/CSGALNACT1/GUK1/RENBP/PMM2/PARG/SLC35D1/GNPNAT1/GALT/SLC35A3/UAP1L1/GFPT1/GNE/GFPT2/GMDS/DPAGT1	20
BP	GO:0032620	interleukin-17 production	20/7096	38/18670	0.04699	0.1623	0.121	MYD88/NOD2/IL27RA/ARG2/LY9/IL15/TGFB1/TLR4/ZBTB7B/IL6/SPHK1/OSM/IL18/TNFSF4/IFNG/IL12B/PRKCQ/NR1H4/IL23A/RFTN1	20
BP	GO:0046636	negative regulation of alpha-beta T cell activation	20/7096	38/18670	0.04699	0.1623	0.121	ANXA1/ARG2/TNFRSF14/BCL6/SMAD7/IL4R/CBFB/HFE/LILRB1/SOCS5/ZBTB7B/HMGB1/CD300A/CD274/LGALS9/HLX/TNFSF4/SOCS1/TBX21/TWSG1	20
BP	GO:0097064	ncRNA export from nucleus	20/7096	38/18670	0.04699	0.1623	0.121	TSC1/NUP62/NUP160/NUP214/RAN/NUP85/SEH1L/NUP43/NPM1/POM121/XPOT/NUP88/NUP107/NUP93/SSB/NUP205/PHAX/NUP50/POM121C/AAAS	20
BP	GO:1905898	positive regulation of response to endoplasmic reticulum stress	20/7096	38/18670	0.04699	0.1623	0.121	PTPN2/PPP1R15A/PMAIP1/BCAP31/EDEM1/SGTA/NCK1/TMEM33/SIRT1/EDEM2/RNFT1/BCL2L11/SERINC3/UBQLN2/BAX/NFE2L2/ATXN3/RNF185/ERN1/BAK1	20
BP	GO:0071375	cellular response to peptide hormone stimulus	137/7096	321/18670	0.04706	0.1624	0.1211	CRHBP/SH2B2/ATP6V0D2/FYN/PDK4/PRKAR2B/APPL2/SOCS3/NR4A2/LYN/POR/TSC1/CSK/SRSF5/SRD5A1/ATP6AP1/RAP1B/STAT6/STAT3/PTPN2/CCND3/ATP6V1C1/ADIPOR1/STAT1/JAK2/GSTP1/PRKACB/C2CD5/ATP6V0C/SLC9A1/CISH/NFKB1/GSK3B/GAB1/RAB31/PIK3R3/KAT2B/GKAP1/PKM/RELA/PDK2/SLC2A8/CDK4/TGFB1/PAK1/ENHO/MYO5A/PCK2/LEP/SYAP1/PRKCD/INSR/BAIAP2/TCIRG1/ZBTB7B/IGF1R/NCK1/ATP6V1A/GCLC/STAT5A/IL1B/AGTRAP/SIK2/SHC1/PHIP/CREB1/CRK/RAB8A/ATP6V1G3/SIRT1/ARID1B/EIF4EBP2/ATP6V1B2/ADCY7/IRS2/CYFIP1/MYO1C/DENND4C/MBD5/ADCY1/ATP6V1D/PTK2/GRB10/ADCY3/GNAI2/ATP6V0E2/INPP5K/GPR21/RHOQ/CPEB1/PRKACA/KANK1/NDEL1/PPAT/GRB2/CYBA/FOXO4/FER/CAMK2A/ATP6V1G2/PXN/NFE2L2/SERPINA12/AHCYL1/RAB8B/SLC25A33/KL/WNT1/PRKAA1/MDM2/PID1/SOCS1/ZNF106/OGT/NR4A3/CCNA2/MEN1/YWHAG/SLA2/PRKCZ/PRKCQ/HDAC5/ATP6V1B1/SLC30A10/SMARCC1/GCG/GHR/ROCK2/APPL1/SOCS2/NUCKS1/NR1H4/STXBP4/MGARP/CPEB2/FOXO3/GHRL	137
BP	GO:0070126	mitochondrial translational termination	42/7096	89/18670	0.04774	0.1647	0.1228	MRPS6/MRPL35/MRPL45/CHCHD1/MRPL40/MRPS30/MRPL34/MRPS16/MRPS14/MRPL54/MRPL44/MRPL33/MRPL51/OXA1L/GFM2/MTRF1L/MRPL49/MRPL3/MRPL42/DAP3/MRPS34/MRPL4/GADD45GIP1/MRPS33/MRPL20/MRPL46/MRPS18B/MRPL24/MRPL36/MRPS25/MRPS15/MRPL48/MTRF1/AURKAIP1/MRPL41/MRPL2/MRPS2/MRPS9/MRPL30/MRPL1/MRRF/MRPS17	42
BP	GO:0000460	maturation of 5.8S rRNA	15/7096	27/18670	0.04816	0.1656	0.1235	KRI1/ABT1/RPS21/LAS1L/EXOSC2/FTSJ3/EXOSC7/RCL1/ERI3/MPHOSPH6/EXOSC9/EXOSC3/EXOSC8/C1D/RRS1	15
BP	GO:0035902	response to immobilization stress	15/7096	27/18670	0.04816	0.1656	0.1235	SLC8A1/FOS/LRP11/HNMT/ACTR2/TGFB1/PTK2B/CYP1A2/ERCC1/PITX3/FOXO4/MDM2/REN/UCN3/FOXO3	15
BP	GO:0046885	regulation of hormone biosynthetic process	15/7096	27/18670	0.04816	0.1656	0.1235	VDR/POR/ATP1A1/EGR1/TNF/AKR1C3/NFKB1/HIF1A/BMP2/IL1B/PPARGC1A/BMP5/ARNT/CYP27B1/IFNG	15
BP	GO:0048668	collateral sprouting	15/7096	27/18670	0.04816	0.1656	0.1235	SPP1/ULK2/IFRD1/ZEB2/ABL1/SEMA4D/LRP1/DCC/LPAR3/IST1/FSTL4/DVL1/APP/CRABP2/FGF13	15
BP	GO:0002763	positive regulation of myeloid leukocyte differentiation	27/7096	54/18670	0.04817	0.1656	0.1235	FOS/ATP6AP1/KLF10/KITLG/TNF/CD74/TESC/HCLS1/TGFB1/ROR2/TRAF6/CASP8/CREB1/TYROBP/TMEM64/ID2/EVI2B/FADD/DCSTAMP/TREM2/IFNG/CD4/RB1/IL12B/SLC9B2/PRKCA/IL23A	27
BP	GO:0046164	alcohol catabolic process	27/7096	54/18670	0.04817	0.1656	0.1235	CYP27A1/GK/SCARB1/AKR1C3/INPP1/APOE/TPI1/SYNJ1/ALDH2/SYNJ2/OCRL/NUDT3/GK5/INPP5K/IMPA2/MTMR2/SORD/AKR1B10/SRD5A3/SULT1B1/CYP46A1/ADH7/NTSR1/HAO1/SNX17/INPP5A/IMPA1	27
BP	GO:0033500	carbohydrate homeostasis	105/7096	242/18670	0.04835	0.1662	0.1239	HK3/PDK4/TRA2B/APPL2/GCLM/STAT3/PTPN2/ADIPOR1/ENY2/CYB5R4/HMGCR/LRP5/PDK2/PPP3CB/SIN3A/AACS/UNC13B/FIS1/ARRB1/HIF1A/FFAR2/WFS1/PIM3/PCK2/LEP/SRF/INSR/MCU/CEBPA/IGF1R/GCLC/AGER/C2CD2L/RAP1A/MPC2/LRP1/CRTC2/RAF1/SIRT1/TRPM4/RAC1/IRS2/ZNF236/PPARGC1A/KLF7/MBD5/BACE2/SRI/OXCT1/POLG/RPH3AL/GPR27/INPP5K/GPR21/NME1/RMI1/PRKACA/LGALS1/SLC16A1/PDX1/FOXK2/CYBA/PTPRN2/FOXO4/HMGN3/FABP5/ASPSCR1/NMB/CAV3/CMA1/ADIPOR2/PRKAA1/TCF7L2/BAD/PLA2G6/HNF1A/KIF5B/SUCNR1/MEN1/DBH/WDR35/PYGL/STXBP3/ZBTB20/NDUFAF2/MAP4K4/TRPV4/ERN1/SLC9B2/SOX4/SIDT2/GCG/ENDOG/KLF15/NUCKS1/NR1H4/STXBP4/SESN2/RBP4/G6PC/PTCH1/FOXO3/GHRL/MIR146A/PHPT1	105
BP	GO:0051702	interaction with symbiont	39/7096	82/18670	0.04851	0.1666	0.1242	FN1/RAB9A/AZU1/GAPDH/CHD1/APOE/PTX3/NAPEPLD/DDB1/TFAP4/IFI27/IGF2R/TAF11/CCL5/CTDP1/PSMC3/CCL8/TBC1D20/INPP5K/CCNK/CFL1/ANXA2P2/FMR1/FBXL2/SMC3/CTSG/EIF2AK4/GPX1/PC/CSF1R/ANXA2/HPN/CCNT1/CCL4/PPIB/NUCKS1/TARDBP/APCS/CXCL6	39
BP	GO:0050684	regulation of mRNA processing	62/7096	137/18670	0.0489	0.1679	0.1252	CELF6/TRA2B/NSRP1/JMJD6/SRSF5/BARD1/ZC3H14/PAF1/KHDRBS1/DAZAP1/RNPS1/THRAP3/RBM7/ZBTB7A/RBM42/SRSF10/HNRNPK/MBNL1/YTHDC1/RBM4/RBM4B/HNRNPA1/HNRNPA2B1/RBM8A/DHX9/SRPK2/SFSWAP/SRSF3/SLTM/MBNL3/CDK9/RBMXL1/PAPOLA/RBM3/SNRPA/CWC22/SRSF6/PRDX6/SREK1/CPEB1/SRSF7/SF3B4/SRPK1/CPEB3/LEO1/RNF20/AHCYL1/C1QBP/FMR1/CELF2/SRSF4/ZC3H10/RBM25/PRPF19/CELF3/HMX2/CCNT1/SRRM4/CDC73/SAP18/CPSF7/SON	62
BP	GO:0032370	positive regulation of lipid transport	30/7096	61/18670	0.04901	0.1682	0.1254	RETN/ATP8A1/SPP1/MIF/P2RX7/NFKBIA/SCP2/APOE/PRELID1/NR1H2/PRKCD/ABCA1/IL1B/LRP1/TNFRSF11A/SIRT1/FABP3/ABCG1/NR1H3/ABCB4/ABCA7/ANXA2P2/GALR1/APOA1/PLA2G6/ANXA2/TRIAP1/PTCH1/NTSR1/GHRL	30
BP	GO:0006695	cholesterol biosynthetic process	36/7096	75/18670	0.04904	0.1682	0.1254	POR/SOD1/NFYC/GPAM/SQLE/RAN/APOE/HMGCR/HMGCS1/SCD/ERLIN1/CNBP/ACLY/ERLIN2/FDPS/ACACB/G6PD/FGF1/ARV1/TM7SF2/APOA5/MSMO1/IDI1/SCAP/ABCG1/SC5D/SREBF2/CYB5R3/INSIG1/ACAA2/PRKAA1/APOA1/MBTPS2/ELOVL6/MBTPS1/KPNB1	36
BP	GO:0034504	protein localization to nucleus	113/7096	262/18670	0.04962	0.1701	0.1268	FYN/GBP2/CDKN1A/SUN2/APPL2/PARP9/TXNIP/LMNA/STAT3/BARD1/NUP62/IPO13/PTGS2/CHP1/FLNA/NUP214/PAF1/NFKBIA/TNPO1/RAN/GSK3B/SUPT7L/HCLS1/ZBTB7A/TGFB1/SIN3A/RAB23/NUP85/NXT1/CBLB/CD36/LEP/RASSF5/PRKCD/PTTG1IP/LILRB4/BANP/HYAL2/KPNA4/KAT7/CDK5/SP100/ZPR1/SNUPN/UBR5/MMP12/MDFIC/POM121/PML/CHCHD10/BMP7/MFHAS1/MAVS/LRRK2/FLCN/NOLC1/DNAJB6/SUMO1/MCRS1/BBS4/IPO4/DTX3L/TOR1A/DCLK2/BMP4/NUP88/RPF2/CSE1L/NUP107/CD2AP/CCT4/CALR/NXT2/ABCA7/FBXO4/CCT8/TXN/NUP93/NOL8/IPO9/TRIM29/DVL1/PSEN1/MDM2/IPO7/MAPK1/YWHAE/KPNA1/NUP50/IFNG/ARNTL/CLDN18/CHP2/TNPO3/PIN1/RANBP6/CARD10/NPAP1/MSX1/PKIA/TERT/SPRN/TOPORS/ARL2BP/ZBTB16/MBTPS1/KPNB1/APPL1/SMO/RRS1/TARDBP/SESN2/POM121C	113
BP	GO:1902743	regulation of lamellipodium organization	23/7096	45/18670	0.05009	0.1716	0.1279	RAC2/ENPP2/CD44/TWF2/RAC1/ARPIN/CORO1B/DNM2/HDAC4/KANK1/FER/DMTN/CORO1C/BIN3/SLIT2/FSCN1/WNT1/ATP7A/HRG/ARPC2/MTOR/WAS/NCKAP1	23
BP	GO:0098727	maintenance of cell number	71/7096	159/18670	0.05023	0.172	0.1282	KLF4/IGF1/DLL1/SPI1/SKI/NOTCH2/RBPJ/STAT3/KLF10/ZNF358/SMAD2/MED10/LDB1/EZH2/PAF1/METTL14/ZNF322/NCOA3/PCM1/METTL3/LOXL2/ASCL2/PAX8/MED15/POLR2L/MED27/MED28/RAF1/SAV1/BMP7/BCL9L/TAL1/POLR2H/ASPM/BMPR1A/HOOK3/KDM2B/SETD6/LIG4/POLR2F/MED30/HES1/POLR2D/LEO1/VPS72/POLR2K/SS18/SMC3/ZFP36L2/HNF1B/DIS3L2/EIF4E/FANCD2/FZD7/ELF5/ESRRB/NR2E1/FOXP1/CDC73/ZNF706/SOX4/SRRT/WNT7A/POLR2I/GNL3/ZSCAN10/SMO/LBH/EIF4ENIF1/TET1/FOXO3	71
BP	GO:0000154	rRNA modification	19/7096	36/18670	0.05058	0.1729	0.1289	NAF1/TFB1M/TRMT112/TRMT61B/RPUSD2/NAT10/THUMPD1/FBL/NHP2/GAR1/FTSJ3/FDXACB1/DIMT1/ZCCHC4/METTL15/MRM1/FBLL1/NSUN5P1/NOP10	19
BP	GO:0010573	vascular endothelial growth factor production	19/7096	36/18670	0.05058	0.1729	0.1289	CCR2/PTGS2/ATF4/NDRG2/TGFB1/CYP1B1/HIF1A/IL1B/IL6ST/IL6/SULF2/C3AR1/HPSE/ADORA2B/IL1A/ARNT/BRCA1/RORA/MIR146A	19
BP	GO:0032733	positive regulation of interleukin-10 production	19/7096	36/18670	0.05058	0.1729	0.1289	NOD2/TLR2/CLEC7A/LILRA5/HGF/IL20RB/TLR4/HMGB1/TIGIT/CD274/LGALS9/TNFSF4/TREM2/TSLP/CD34/IL12B/PRKCZ/CD83/IL23A	19
BP	GO:0008033	tRNA processing	59/7096	130/18670	0.0507	0.1732	0.1291	TRMT6/SEPHS2/DPH3/ALKBH1/FTSJ1/TPRKB/OSGEPL1/FAM98B/ELP4/RPP38/TRMT5/TRMT1/TYW3/BCDIN3D/DUS2/LCMT2/TRMT112/TRMT61B/RPP25/ELAC1/NSUN2/TRMT1L/RPP14/PUS1/TP53RK/CLP1/NAT10/OSGEP/THUMPD1/METTL1/ELP3/METTL8/HSD17B10/DDX1/QTRT1/WDR4/ALKBH8/THUMPD2/MOCS3/TRMT11/THUMPD3/SSB/RPP40/ELP2/MTFMT/RPPH1/POP7/ADAT2/MTO1/C2orf49/CPSF1/DUS1L/TRMT10C/PUS7/GTPBP3/NSUN6/AARS2/POLR3K/ADAT1	59
BP	GO:0042136	neurotransmitter biosynthetic process	49/7096	106/18670	0.05083	0.1735	0.1293	KLF4/NQO1/KLF2/CX3CR1/ATP2B4/ACP5/GCH1/CLEC7A/ARG2/ALDH9A1/PTGS2/JAK2/TNF/DDAH2/PKD2/TICAM1/CYP1B1/CD36/PTK2B/INSR/HBB/PTX3/TLR4/DPYD/IL1B/AIF1/CLU/RAC1/GLA/SPR/DAGLB/SHMT2/DNM2/CD47/AGXT2/SHMT1/TPH2/RORA/IFNG/SLC7A2/CD34/HSP90AB1/DBH/WDR35/MTOR/CHAT/ROCK2/TLR6/GCHFR	49
BP	GO:0044774	mitotic DNA integrity checkpoint	49/7096	106/18670	0.05083	0.1735	0.1293	CDKN1A/RGCC/HUS1B/GIGYF2/BTG2/TAOK3/ZNF830/SYF2/SETMAR/PLK2/SFN/DONSON/PML/TIPIN/CCND1/ATM/TNKS1BP1/MUC1/PLK3/RAD17/PCNA/BAX/CRADD/CASP2/RFWD3/CDKN1B/TOP2B/CNOT4/PLAGL1/ARID3A/FOXO4/TICRR/E2F4/CNOT7/GML/MDM2/CLSPN/RBL2/RAD9A/TOPBP1/CNOT10/CARM1/TRIAP1/AURKA/BRSK1/SOX4/PRMT1/E2F8/TOP2A	49
BP	GO:0001562	response to protozoan	14/7096	25/18670	0.05149	0.1752	0.1306	GBP2/CLEC7A/SLC11A1/CD40/IL4R/BATF/CCDC88B/GBP4/TSPAN32/HRAS/BATF2/IRF8/GBP6/IL12B	14
BP	GO:0021952	central nervous system projection neuron axonogenesis	14/7096	25/18670	0.05149	0.1752	0.1306	NR4A2/EPHB2/ZEB2/SCN1B/FBXO45/ADARB1/PAFAH1B1/DCC/MYCBP2/TSKU/SLIT2/CHRNB2/EPHB1/NR2E1	14
BP	GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway	14/7096	25/18670	0.05149	0.1752	0.1306	CD55/TNFAIP3/MIF/LY96/LY86/LILRA2/CD36/TRAF6/CACTIN/SIGIRR/LACRT/CX3CL1/PRKCA/SASH1	14
BP	GO:0044247	cellular polysaccharide catabolic process	14/7096	25/18670	0.05149	0.1752	0.1306	MANBA/MGAM/AGL/PPP1R3D/PHKB/PHKG1/PGM2/PPP1R3B/PPP1CA/GAA/PYGM/PPP1CB/PYGL/G6PC	14
BP	GO:0045830	positive regulation of isotype switching	14/7096	25/18670	0.05149	0.1752	0.1306	MAD2L2/STAT6/CD40/PTPRC/TGFB1/MLH1/CLCF1/TFRC/TNFSF4/EXOSC3/TBX21/EXOSC6/PAXIP1/ATAD5	14
BP	GO:1900101	regulation of endoplasmic reticulum unfolded protein response	14/7096	25/18670	0.05149	0.1752	0.1306	PTPN2/PPP1R15A/WFS1/HSPA5/NCK1/TMEM33/PPP1R15B/BCL2L11/BAX/DNAJB9/BFAR/ERN1/BAK1/ATF6B	14
BP	GO:0030072	peptide hormone secretion	108/7096	250/18670	0.05158	0.1754	0.1308	CRHBP/ANXA1/ACVR2B/PPARD/HADH/SIRT4/SMAD2/ENY2/PER2/CYB5R4/JAK2/FAM3D/HFE/TNF/HMGCR/DPP4/LRP5/PPP3CB/ITPR1/AACS/ARRB1/HIF1A/FFAR2/PIM3/ENHO/MYO5A/LEP/MCU/AIMP1/TCIRG1/ITSN1/PAX8/IL1B/UQCC2/CCL5/C2CD2L/RAP1A/MPC2/LRP1/RAF1/RFX3/IL1RN/TRPM4/DOC2B/RAC1/GLUD1/IL6/KALRN/IRS2/SLC25A5/KLF7/SERP1/SRI/OXCT1/RPH3AL/GPR27/SLC16A1/SYTL4/CPT1A/PDX1/TM7SF3/PTPRN2/PFKFB2/HMGN3/RAB8B/EGFR/ICA1/CLOCK/GIPR/TCF7L2/EXOC3L1/LTBP4/BAD/SYT9/PLA2G6/HNF1B/IFNG/HNF1A/ARNTL/VIP/SNX19/KIF5B/STXBP3/NDUFAF2/MAP4K4/TRPV4/GHRH/SLC9B2/SOX4/SIDT2/ARL2BP/RIMS2/GCG/PFKL/NLGN2/GJA1/NR1H4/TARDBP/STXBP4/PRKCA/UCN3/RBP4/PSMD9/TACR2/GHRL/KISS1/APLN/PHPT1	108
BP	GO:0099518	vesicle cytoskeletal trafficking	26/7096	52/18670	0.05188	0.1763	0.1315	BLOC1S2/ACTN4/KIF3B/KIFAP3/MYO5A/AP3M2/TRAK2/PAFAH1B1/DTNBP1/CLN3/RASGRP1/BLOC1S6/MYO1C/BLOC1S3/NDEL1/KIF13A/BLOC1S1/BLOC1S4/AP3B1/KIF1B/AP3M1/KIF5B/TRAK1/PRKCZ/KIF1C/TRIM46	26
BP	GO:0060538	skeletal muscle organ development	75/7096	169/18670	0.05201	0.1767	0.1317	HIVEP3/FOS/DLL1/SKI/DISP1/GPCPD1/FLOT1/KLHL41/VAMP5/EGR1/NUPR1/HMGCR/BTG2/MYL6B/TGFB1/CFL2/RYR1/CDK5/SVIL/EMD/UQCC2/NR1D2/S100B/BASP1/HOMER1/EGR2/BCL9L/NLN/MYL6/MYOG/BCL2/CYP26B1/HDAC4/KCNAB1/KLF5/YBX3/ZBTB18/KLHL40/HLX/FGFRL1/FLNB/MYOZ1/COPS2/LMOD3/BIN3/MYOM2/PRKAA1/SHOX2/DNER/CNTFR/CASQ1/MEGF10/EPHB1/ARNTL/HLF/RB1/ZNF689/GPX1/PITX1/RHOA/TAZ/HMG20B/PAX7/P2RX2/PAX5/USP19/WNT10B/ACTA1/SMO/WT1/KEL/TLL2/MEF2C/MYF6/STRA6	75
BP	GO:0140029	exocytic process	38/7096	80/18670	0.05204	0.1767	0.1317	LYN/STX11/CTBP2/EXOC6B/STXBP1/UNC13B/STXBP2/SYNJ1/VAMP3/VPS33A/BLOC1S6/RAB8A/P2RX1/VPS18/NAPA/PLEK/CAMK2A/DMTN/YKT6/RAB8B/PSEN1/RAB3A/PPFIA3/VTI1B/SYT9/SYTL2/EXOC4/SYT1/RAB3B/SCFD1/SNX4/VAMP1/STXBP3/SNAP29/CADPS2/RABEPK/RAB3D/SNCA	38
BP	GO:0001678	cellular glucose homeostasis	68/7096	152/18670	0.05229	0.1773	0.1322	HK3/TRA2B/GCLM/ENY2/HMGCR/LRP5/PPP3CB/SIN3A/AACS/UNC13B/FIS1/ARRB1/HIF1A/PIM3/PCK2/SRF/IGF1R/GCLC/AGER/C2CD2L/RAP1A/MPC2/LRP1/RAF1/SIRT1/TRPM4/RAC1/IRS2/ZNF236/PPARGC1A/KLF7/SRI/OXCT1/POLG/GPR27/NME1/PRKACA/LGALS1/PDX1/FOXK2/CYBA/PTPRN2/HMGN3/CMA1/PRKAA1/BAD/PLA2G6/KIF5B/MEN1/WDR35/STXBP3/ZBTB20/NDUFAF2/MAP4K4/ERN1/SLC9B2/SOX4/SIDT2/GCG/ENDOG/KLF15/NUCKS1/NR1H4/STXBP4/FOXO3/GHRL/MIR146A/PHPT1	68
BP	GO:0051028	mRNA transport	68/7096	152/18670	0.05229	0.1773	0.1322	ZFP36/NXF1/SRSF5/NUP62/NUP160/CHTOP/NUP214/ENY2/G3BP2/AGFG1/ALYREF/RNPS1/MX2/MAGOHB/SARNP/NUP85/NXT1/CETN3/SEH1L/YTHDC1/BICD2/NUP43/HNRNPA1/HNRNPA2B1/RBM8A/MVP/FYTTD1/DDX19B/DHX9/U2AF1/POM121/SRSF3/SYMPK/CPSF3/MYO1C/ARC/FIP1L1/NUP88/THOC2/SRSF6/SRSF7/NUP107/CDC40/NPIPA1/THOC5/POLR2D/NXT2/U2AF1L4/EIF5A/NUP93/CETN2/THOC6/SRRM1/NUP205/FMR1/SRSF4/EIF4E/NUP50/PARP11/DHX38/MCM3AP/PCID2/HNRNPA3/CPSF2/CPSF1/POM121C/AAAS/UPF1	68
BP	GO:0006694	steroid biosynthetic process	86/7096	196/18670	0.05264	0.1783	0.133	VDR/ASAH1/HSD17B14/POR/STARD4/CYP27A1/SOD1/ATP1A1/SRD5A1/AKR1B1/NFYC/GPAM/DDX20/CYB5R1/OSBPL9/FAXDC2/SCARB1/SQLE/EGR1/TNF/SCP2/AKR1C3/NFKB1/RAN/IGFBP7/APOE/HMGCR/OSBPL1A/HMGCS1/SCD/LEP/ERLIN1/CNBP/BMP2/ACLY/IL1B/HSD11B1/STARD3NL/ERLIN2/FDPS/SLC27A2/HSD17B4/ACACB/ACOX2/SIRT1/G6PD/PPARGC1A/FGF1/ARV1/TM7SF2/APOA5/MSMO1/IDI1/PRKAG2/BMP5/SCAP/ABCG1/SC5D/ACBD3/CH25H/OSBPL2/ABCB11/SREBF2/CYB5R3/FDX1/INSIG1/HINT2/ACAA2/SRD5A3/PRKAA1/HSD17B3/APOA1/CYP27B1/SNAI1/IFNG/TFCP2L1/SDR42E1/MBTPS2/ELOVL6/MBTPS1/KPNB1/CYP46A1/CACNA1H/NR1H4/HSD17B12/ACOT8	86
BP	GO:0072401	signal transduction involved in DNA integrity checkpoint	35/7096	73/18670	0.05267	0.1783	0.133	CDKN1A/RGCC/BTG2/UIMC1/PLK2/SFN/PML/ATM/TNKS1BP1/MUC1/PLK3/PCNA/BAX/CRADD/CASP2/CDKN1B/CNOT4/PLAGL1/ARID3A/DTL/E2F4/BRCA1/CNOT7/GML/MDM2/RBL2/CNOT10/PRPF19/CARM1/TRIAP1/AURKA/SOX4/BRCC3/PRMT1/E2F8	35
BP	GO:0072422	signal transduction involved in DNA damage checkpoint	35/7096	73/18670	0.05267	0.1783	0.133	CDKN1A/RGCC/BTG2/UIMC1/PLK2/SFN/PML/ATM/TNKS1BP1/MUC1/PLK3/PCNA/BAX/CRADD/CASP2/CDKN1B/CNOT4/PLAGL1/ARID3A/DTL/E2F4/BRCA1/CNOT7/GML/MDM2/RBL2/CNOT10/PRPF19/CARM1/TRIAP1/AURKA/SOX4/BRCC3/PRMT1/E2F8	35
BP	GO:1902108	regulation of mitochondrial membrane permeability involved in apoptotic process	32/7096	66/18670	0.05295	0.1792	0.1336	BMF/SLC35F6/BLOC1S2/PMAIP1/YWHAH/TMEM14A/GSK3B/MPV17L/FZD9/SFN/CASP8/RHOT2/CHCHD10/SLC25A5/BCL2L11/MAPK8/TMEM102/BCL2/BAX/GZMB/THEM4/YWHAQ/CAMK2A/MUL1/ACAA2/YWHAE/BAD/PPP1R13B/NAIF1/MOAP1/YWHAG/BAK1	32
BP	GO:1904894	positive regulation of STAT cascade	43/7096	92/18670	0.0536	0.1813	0.1352	IGF1/FYN/SOCS3/LYN/PARP9/AKR1B1/STAT3/MGAT5/ADIPOR1/CD40/JAK2/IL15/TNF/IL7R/HCLS1/CYP1B1/PTK2B/LEP/FLT3/PTK6/CCL5/TNFRSF18/IL6ST/IL6/HDAC2/CLCF1/OSM/CD300A/HES1/F2R/CNTF/IL18/SOCS1/IL3/TSLP/IFNG/TNFSF18/IL12B/CSF1R/ARL2BP/GHR/IL26/IL23A	43
BP	GO:0052548	regulation of endopeptidase activity	178/7096	425/18670	0.05385	0.1821	0.1357	KLF4/S100A9/S100A8/SERPINA1/RARRES1/SERPINB2/FYN/SERPINB9/CDKN2D/CLEC7A/CST6/BCL10/LYN/POR/AIFM1/GRAMD4/STAT3/PROS1/CTSD/PTGS2/PSMB9/GAPDH/TIMP2/NLRP3/TNFRSF10A/TFPI/SH3RF1/PMAIP1/RPS6KA3/LXN/PSMB8/MBP/BIRC2/UBE2Z/LGMN/CD44/MYC/NLRP12/PZP/JAK2/LAMP3/FAS/BCAP31/A2M/TNF/PEBP1/IFT57/PRELID1/PSME1/CST3/AIM2/MICAL1/HGF/ARL6IP1/FIS1/ARRB1/CAST/SERPINB1/TFAP4/HTRA2/VEGFA/RENBP/SFN/CYFIP2/SERPINB8/TNFSF10/CASP8/PAK2/FURIN/CPAMD8/AGER/ADRM1/DAPK1/PML/CASP5/HMGB1/WFDC12/TRADD/RAF1/PPM1F/SIRT1/UCHL5/SERPING1/TTBK1/LCK/PLAUR/CR1/EGLN3/SPINK1/DNAJB6/TIMP4/PDCD5/SERPINA9/DDX3X/WFDC1/CST7/PRR7/FNIP1/BCL2L11/P2RX1/PSME3/MMP9/MEFV/BAX/SERPINE1/CRADD/COL7A1/TIMP1/BIRC3/SPINT1/CASP1/CSTA/KHDC1/SPOCK2/LGALS9/RFFL/ST20/AMBP/BIRC7/MAP3K5/F2R/LAMTOR5/CAAP1/TNFRSF10B/SERPINI2/SERPINA12/MUL1/FADD/TRAF2/CASP4/WFIKKN1/MDM2/YWHAE/COL4A3/BAD/DAP/SERPINA7/NLRP1/IGBP1/ST18/SPOCK1/HRG/CRIM1/SERPINB4/COL6A3/A2ML1/PCID2/SPINT3/MAP2K5/SPINK6/NLRP2/WDR35/DIABLO/F3/SERPINB6/GPX1/VCP/PI3/RHOA/TRIAP1/APP/SNCA/MALT1/BAK1/SERPINB10/XIAP/MGMT/PICALM/ROCK2/AKIRIN2/SERPINF2/BIN1/ITIH3/SIAH2/MIR205/CD109/EFNA3/SOX7	178
BP	GO:0032365	intracellular lipid transport	22/7096	43/18670	0.05399	0.1823	0.1359	STARD4/NPC2/SLC25A20/SCP2/CPT2/ABCA1/LDLR/ACACB/FABP3/ARV1/PLEKHA8/PRKAG2/ABCG1/CPT1A/OSBPL2/NUS1/ANXA2P2/PLEKHA3/SERAC1/ANXA2/THRSP/PLEKHA8P1	22
BP	GO:0060612	adipose tissue development	22/7096	43/18670	0.05399	0.1823	0.1359	PPARD/SLC25A25/ZNF516/LRP5/CDK4/ARRDC3/AACS/LEP/DYRK1B/SPTLC2/SIRT1/TRPM4/DGAT2/PPARGC1A/KLF7/BBS4/OXCT1/FTO/ID2/PAXIP1/NR1H4/GHRL	22
BP	GO:0030593	neutrophil chemotaxis	48/7096	104/18670	0.0543	0.1829	0.1363	S100A9/S100A8/S100A12/RAC2/BST1/CAMK1D/PPBP/CXCL9/CXCL11/CD74/CXCL10/MPP1/CXCL13/PDE4B/IL1B/CCL5/CCL7/IL1RN/RAC1/CXCR1/CKLF/C3AR1/MOSPD2/CCL13/CCL8/PIK3CD/C1QBP/VAV1/CXCR2/CCL20/JAM3/PREX1/SLIT2/CCL26/CSF3R/PIK3CG/LBP/C5AR2/DAPK2/CX3CL1/CCL19/TIRAP/CCL4/CCR7/CCL24/IL23A/CXCL6/IL37	48
BP	GO:2000045	regulation of G1/S transition of mitotic cell cycle	81/7096	184/18670	0.0543	0.1829	0.1363	KLF4/PTPN6/ANXA1/CDKN2D/CDKN1A/GPNMB/CCND3/MEPCE/ZNF655/RGCC/SLFN11/EZH2/LSM11/PKD2/GIGYF2/PSME1/BTG2/CCND2/CDK4/RDX/CDKN2B/PLK2/SFN/AIF1/PML/CDK2AP2/CCND1/DDX3X/ATM/TNKS1BP1/MUC1/KMT2E/CTDSPL/PLK3/PSME3/NACC2/UBE2E2/CCNE1/BCL2/PCNA/BAX/ANKRD17/CRADD/ID2/CASP2/CTDSP1/RFWD3/CDKN1B/CDKN2C/CNOT4/FHL1/PLAGL1/ARID3A/BTN2A2/E2F4/PLCB1/EGFR/CNOT7/GML/ADAM17/CTDSP2/MDM2/EIF4G1/WEE1/RBL2/MTBP/DCUN1D3/CUL4B/TMEM14B/RB1/CNOT10/CARM1/JADE1/TERT/TRIAP1/AURKA/CDC73/SOX4/PRMT1/KIF14/E2F8	81
BP	GO:0007569	cell aging	53/7096	116/18670	0.05436	0.1829	0.1363	NAMPT/CDKN1A/LMNA/SOD1/ARG2/NUP62/BCL6/MIF/MAP2K1/KRAS/SMC5/EEF1E1/VASH1/SMC6/PRKCD/SRF/ZKSCAN3/MNT/CDKN2B/PLK2/HRAS/NPM1/ABL1/NSMCE2/HMGA1/PML/SIRT1/HLA-G/YPEL3/ATM/MIR34A/MAPKAPK5/BMPR1A/BCL2/SERPINE1/ERCC1/ID2/ZMPSTE24/CALR/KIR2DL4/ATR/WNT1/ARNTL/TERT/MTOR/LIMS1/ENG/PDCD4/PNPT1/SLC30A10/NEK4/ZNF277/MIR146A	53
BP	GO:0034219	carbohydrate transmembrane transport	53/7096	116/18670	0.05436	0.1829	0.1363	IGF1/PEA15/APPL2/SLC5A3/MEF2A/TSC1/SLC23A2/PPARD/PPBP/SLC45A3/SLC2A3/SLC2A6/TNF/C2CD5/SLC2A9/TMEM144/SLC2A8/LEP/INSR/IL1B/RAP1A/CREBL2/IRS2/RTN2/ITLN1/CLTCL1/GRB10/PRKAG2/INPP5K/RHOQ/FFAR4/RNASEL/SLC50A1/SLC5A4/SLC17A5/NFE2L2/FABP5/ASPSCR1/ADIPOR2/PID1/SLC2A10/HNF1A/NR4A3/TERT/STXBP3/SLC5A10/CLIP3/SLC5A9/APPL1/SLC5A2/KLF15/STXBP4/SESN2	53
BP	GO:0002183	cytoplasmic translational initiation	18/7096	34/18670	0.05445	0.1829	0.1363	METTL3/RBM4/EIF2D/EIF3M/NCK1/EIF4B/EIF3I/EIF2S2/EIF4H/EIF3G/MCTS1/EIF3B/EIF5/TICRR/EIF3J/EIF4G1/MTOR/EIF3L	18
BP	GO:0006536	glutamate metabolic process	18/7096	34/18670	0.05445	0.1829	0.1363	GCLM/SLC7A11/HAL/ALDH18A1/NAGS/GCLC/ALDH4A1/GLUD1/ADHFE1/ALDH5A1/SLC25A12/GLUD2/GLS/GOT2/FPGS/AMDHD1/ATCAY/NR1H4	18
BP	GO:0007435	salivary gland morphogenesis	18/7096	34/18670	0.05445	0.1829	0.1363	TNF/TGFB1/HGF/BMP7/EDA/PLXNA1/NRP1/PLXND1/EDAR/TGM2/PDGFA/EGFR/TGFB3/BTBD7/POLB/DAG1/TWSG1/LAMA1	18
BP	GO:0016601	Rac protein signal transduction	18/7096	34/18670	0.05445	0.1829	0.1363	RAC2/ARF6/ALS2/KRAS/RHOG/STMN3/AIF1/CRK/NISCH/RAC1/CYFIP1/RHOU/DNM2/HACE1/RASGRF1/ELMO1/OGT/NCKAP1	18
BP	GO:0071868	cellular response to monoamine stimulus	18/7096	34/18670	0.05445	0.1829	0.1363	ATP2B4/SRD5A1/GNB1/SLC9A1/ATF4/SIN3A/PDE4B/ABL1/LRRK2/GNG2/HDAC2/DNM2/PRKACA/KCNQ1/MAPK1/NR4A3/APP/SNCA	18
BP	GO:0071870	cellular response to catecholamine stimulus	18/7096	34/18670	0.05445	0.1829	0.1363	ATP2B4/SRD5A1/GNB1/SLC9A1/ATF4/SIN3A/PDE4B/ABL1/LRRK2/GNG2/HDAC2/DNM2/PRKACA/KCNQ1/MAPK1/NR4A3/APP/SNCA	18
BP	GO:0097009	energy homeostasis	18/7096	34/18670	0.05445	0.1829	0.1363	METRNL/DLL1/STAT3/CD36/OMA1/MEX3C/NR1D2/ACACB/PPARGC1A/FLCN/CRTC1/CRTC3/AMPD2/PRKAA1/EIF4G1/NR4A3/TRPV4/AMPD3	18
BP	GO:0032102	negative regulation of response to external stimulus	154/7096	365/18670	0.05449	0.1829	0.1363	KLF4/IGF1/FPR2/SERPINB2/RTN4R/PTGER4/METRNL/ACP5/DUSP1/IL1R2/CDKN1A/APPL2/GRN/SOCS3/WNT5A/SOD1/ARG2/SEMA4B/PTPN2/PROS1/LRIG2/SPP1/NLRP3/PPARD/TFPI/DUSP10/TNFAIP3/MIF/FGL2/LILRA2/NLRP12/GSTP1/PTPRC/CERS2/SIGLEC10/NFKB1/APOE/HMGCR/PTPRO/DUSP3/NUCB2/CHID1/HGF/TNFAIP6/SOCS5/MAPK7/LEP/PSMA1/PRKCD/MAPKBP1/CXCL13/SEMA4A/IL20RB/ABR/CACTIN/C5orf30/AIF1/NR1D2/SEMA4C/AGER/LDLR/SEMA4D/THBD/BBS2/CRK/MKKS/MFHAS1/SERPING1/ADCY7/PDGFB/CDH5/PLAUR/CD200R1/CORO1B/BCR/ETS1/WFDC1/CST7/BBS4/MIR34A/SEMA6B/RPS19/NPLOC4/SEC14L1/NRP1/ASH1L/SEMA3B/MEFV/TARBP2/SERPINE1/CDKN1B/SIGLEC11/NR1H3/FFAR4/GPR18/HTRA1/PCBP2/INPP5F/RTN4RL1/PDGFA/RABGEF1/SEMA5A/CNR2/ADA/MYOZ1/CLASP2/C1QBP/MUL1/PPARA/GPATCH3/ANXA2P2/SLIT2/DVL1/RIOK3/SEMA5B/SIGIRR/APOA1/RORA/HAVCR2/PLXNA3/HRG/CD34/NLRX1/RB1/LACRT/CACNB3/IL12B/TRAF3IP1/GPX1/ANXA2/C5AR2/TYRO3/CX3CL1/PDCD4/TSPAN6/ABCD1/TSPAN8/KREMEN1/FOXF1/SPX/NENF/PSMB4/GJA1/GREM1/NR1H4/NLRC3/SLAMF8/SERPINF2/C1QTNF3/FAM3A/MIR205/APCS/GHRL/CD109	154
BP	GO:0009067	aspartate family amino acid biosynthetic process	13/7096	23/18670	0.055	0.184	0.1372	ADI1/MTR/APIP/MTRR/ENOPH1/ASNSD1/PLOD1/MTAP/ASNS/BHMT/PLOD2/GOT2/AASDHPPT	13
BP	GO:0009251	glucan catabolic process	13/7096	23/18670	0.055	0.184	0.1372	MGAM/AGL/PPP1R3D/PHKB/PHKG1/PGM2/PPP1R3B/PPP1CA/GAA/PYGM/PPP1CB/PYGL/G6PC	13
BP	GO:0016578	histone deubiquitination	13/7096	23/18670	0.055	0.184	0.1372	USP51/USP3/ENY2/ATXN7L3/UIMC1/ATXN7/USP16/USP7/KAT2A/USP49/BAP1/USP22/BRCC3	13
BP	GO:0042454	ribonucleoside catabolic process	13/7096	23/18670	0.055	0.184	0.1372	PNP/UPP1/AHCY/HDDC3/CDADC1/APOBEC3G/APOBEC3C/APOBEC2/ADA/APOBEC3B/CDA/ENPP4/ADAL	13
BP	GO:0071425	hematopoietic stem cell proliferation	13/7096	23/18670	0.055	0.184	0.1372	WNT5A/PIM1/ETV6/KITLG/ARIH2/N4BP2L2/EIF2AK2/ATXN1L/WNT1/CD34/WNT2B/WNT10B/THPO	13
BP	GO:1902254	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator	13/7096	23/18670	0.055	0.184	0.1372	MIF/CD44/CD74/PTTG1IP/SIRT1/ELL3/MUC1/BCL2/RRM2B/MDM2/TAF9B/TRIAP1/ATAD5	13
BP	GO:0007224	smoothened signaling pathway	60/7096	133/18670	0.05533	0.185	0.1379	PKD2L1/POR/CHSY1/TCTN1/EVC/IFT172/PRKACB/PDCL/IFT57/DYRK2/TULP3/CTNNA1/MEGF8/ROR2/ARL13B/WDR11/IFT80/FUZ/PTCH2/WDR19/INTU/TUBD1/GORAB/IFT46/IFT52/B9D1/TCTN2/HSPB11/BMP4/WDPCP/HHAT/KCTD11/PRKACA/BBS7/PDX1/MKS1/HIPK1/HES1/TMEM231/GPC2/SHOX2/IFT20/RORA/RB1/GPR161/TRAF3IP1/FBXL17/TCTN3/TTBK2/FOXF1/CD3E/WNT10B/SMO/BOC/KCTD21/IFT81/PTCH1/C2CD3/SCUBE3/GAS8	60
BP	GO:1902115	regulation of organelle assembly	85/7096	194/18670	0.0556	0.1858	0.1385	EZR/STAM/PINK1/ATG3/C9orf72/NUP62/HCK/FEZ2/SEC22B/G3BP2/TNF/SENP6/AKAP13/KCTD17/NUPR1/IL1RAP/KAT2B/KIF9/CHMP4B/TRIM37/RDX/MAP4/FUZ/PLK2/NPM1/CDK5RAP2/RAB3GAP1/ARHGEF2/SDCBP/CEP76/NPRL3/SPAG5/CCDC88A/CYLD/LRRK2/ADAMTS16/ATXN2/BBS4/SYNE2/PHF23/ATXN2L/LCP1/MAK/SPICE1/UBQLN2/DNM2/CHMP2A/TSG101/RAB5A/DYNC2LI1/TBC1D7/CHMP1A/VPS4B/CCDC151/STX18/BRCA1/ULK1/GPSM2/CAV3/FSCN1/KAT2A/PRKAA1/TCHP/MTMR3/CBLN1/SH3GLB1/IFT20/SMCR8/NPRL2/MSN/SMC3/RNF4/SCFD1/RNF5/STAG1/CEP120/VDAC3/RHOA/ASAP1/CHMP1B/RP1/ALMS1/WRAP73/MEF2C/MAPK9	85
BP	GO:0000271	polysaccharide biosynthetic process	37/7096	78/18670	0.05583	0.1862	0.1388	IGF1/EXTL2/NDST2/HS2ST1/B3GNT8/PER2/EXT2/EXT1/NFKB1/GSK3B/AGL/DYRK2/TGFB1/B3GNT2/PPP1R3E/INSR/GYS1/PPP1R3D/GYG2/CSGALNACT1/B3GNT5/IRS2/PDGFB/PHKG1/PGM2/INPP5K/PPP1R3B/NDST1/PPP1R3F/CSGALNACT2/B4GALT5/AP2A1/PPP1CA/B3GNT4/PPP1CB/ESRRB/MTOR	37
BP	GO:0021954	central nervous system neuron development	37/7096	78/18670	0.05583	0.1862	0.1388	NR4A2/WNT5A/TCTN1/ATF5/EPHB2/ZEB2/BTG2/RAPGEF2/LEP/SCN1B/B4GALT6/FBXO45/ADARB1/CDK5/PAFAH1B1/CRK/DCC/MYCBP2/TSKU/PTK2/ARX/DCLK2/NRP1/DISC1/NRP2/NDEL1/B4GALT5/UQCRQ/SLIT2/CHRNB2/EPHB1/PLXNA3/ATP7A/HSP90AB1/NR2E1/LHX6/NTRK2	37
BP	GO:0070664	negative regulation of leukocyte proliferation	37/7096	78/18670	0.05583	0.1862	0.1388	PTPN6/LILRB2/LYN/ARG2/GPNMB/MNDA/LST1/TNFRSF14/TNFAIP3/CEBPB/GSTP1/TNFRSF21/LILRB1/TGFB1/IL20RB/ZBTB7B/CASP3/IDO1/TYROBP/HLA-G/CTLA4/GLMN/ATM/VSIG4/SCGB1A1/PDCD1LG2/CCL8/BMP4/CD300A/CD274/LGALS9/BTN2A2/TNFRSF13B/HAVCR2/CD80/GREM1/TWSG1	37
BP	GO:0090398	cellular senescence	37/7096	78/18670	0.05583	0.1862	0.1388	NAMPT/CDKN1A/ARG2/BCL6/MAP2K1/KRAS/SMC5/EEF1E1/VASH1/SMC6/PRKCD/SRF/ZKSCAN3/CDKN2B/PLK2/HRAS/ABL1/NSMCE2/HMGA1/PML/SIRT1/HLA-G/YPEL3/MIR34A/MAPKAPK5/BMPR1A/ID2/ZMPSTE24/CALR/KIR2DL4/ARNTL/TERT/PNPT1/SLC30A10/NEK4/ZNF277/MIR146A	37
BP	GO:0002931	response to ischemia	25/7096	50/18670	0.05591	0.1862	0.1388	CX3CR1/PINK1/AIFM1/CIB1/UCHL1/SQSTM1/PER2/P2RX7/EGR1/PANX1/ARID1B/PPARGC1A/MLYCD/BCL2/MAP3K5/CAMK2A/STUB1/TREM2/FAIM2/HYOU1/CSF1R/CX3CL1/P2RX2/ROCK2/GJA1	25
BP	GO:0014009	glial cell proliferation	25/7096	50/18670	0.05591	0.1862	0.1388	LYN/SKI/RNF10/CERS2/TNF/PTK2B/ASCL2/IL1B/CREB1/CLU/ETV5/IL6/IDH2/PLAG1/DICER1/LGI4/HES1/PPP1CC/TREM2/TERT/CSF1R/MTOR/CX3CL1/SOX4/MIR146A	25
BP	GO:0070534	protein K63-linked ubiquitination	25/7096	50/18670	0.05591	0.1862	0.1388	NOD2/ZFP91/BIRC2/UBE2N/PLAA/UBE2S/TRAF6/PTPN22/UBR5/RNF115/ARIH2/UBE2E2/NEDD4/UBE2D4/RNF126/STUB1/WWP2/TRAF2/BFAR/RNF4/RNF5/PRPF19/UBE2G1/UBE2B/SASH1	25
BP	GO:0010965	regulation of mitotic sister chromatid separation	28/7096	57/18670	0.0568	0.189	0.1409	DUSP1/MAD2L2/DYNC1LI1/SPDL1/CENPE/KLHL22/CDK5RAP2/NSMCE2/CDC23/ESPL1/ZNF207/LCMT1/ATM/ANAPC5/BUB3/NDC80/GEN1/ZW10/CDC26/RIOK2/DLGAP5/ANAPC4/CDC27/CDC20/PCID2/RB1/ANAPC11/IK	28
BP	GO:0042743	hydrogen peroxide metabolic process	28/7096	57/18670	0.0568	0.189	0.1409	FYN/RAC2/PINK1/SOD1/STAT3/PRDX1/HBB/MPV17L/CAT/GPX3/RAC1/NOXA1/CYP1A2/PRDX6/MMP3/HBQ1/CYBA/CYBB/EGFR/MAOB/HP/DUOXA1/GPX1/SNCA/HBE1/CTNS/MPO/NNT	28
BP	GO:0010257	NADH dehydrogenase complex assembly	31/7096	64/18670	0.05695	0.1893	0.1411	NDUFA8/NDUFC1/NDUFB11/NDUFAF4/NDUFAF7/NDUFS3/NDUFA3/NDUFA11/TIMM21/NUBPL/NDUFA1/NDUFAF3/OXA1L/NDUFA10/NDUFB1/NDUFB5/NDUFS1/NDUFB8/NDUFB6/TIMMDC1/NDUFB3/NDUFS7/NDUFAF2/NDUFV2/ND4/TAZ/NDUFB2/ECSIT/NDUFS2/NDUFA7/TMEM126B	31
BP	GO:0032981	mitochondrial respiratory chain complex I assembly	31/7096	64/18670	0.05695	0.1893	0.1411	NDUFA8/NDUFC1/NDUFB11/NDUFAF4/NDUFAF7/NDUFS3/NDUFA3/NDUFA11/TIMM21/NUBPL/NDUFA1/NDUFAF3/OXA1L/NDUFA10/NDUFB1/NDUFB5/NDUFS1/NDUFB8/NDUFB6/TIMMDC1/NDUFB3/NDUFS7/NDUFAF2/NDUFV2/ND4/TAZ/NDUFB2/ECSIT/NDUFS2/NDUFA7/TMEM126B	31
BP	GO:0030901	midbrain development	42/7096	90/18670	0.05738	0.1906	0.1421	NR4A2/WNT5A/MBP/WLS/YWHAH/NDRG2/ACTB/RAD1/KDM7A/CSNK1D/ZNF148/NDUFS3/HSPA5/CASP5/BASP1/GLUD1/TTBK1/SUDS3/G6PD/CSNK1E/KDM2B/YWHAQ/PITX3/UQCRQ/GNB4/HES1/FZD1/CXCR2/CMA1/MAOB/WNT1/KAT2A/SYNGR3/YWHAE/SYPL2/INA/MAPKAP1/CNP/MSX1/RHOA/LMX1A/PLP1	42
BP	GO:0030282	bone mineralization	52/7096	114/18670	0.05796	0.1924	0.1435	IGF1/SLC8A1/ACVR2B/SBNO2/GPNMB/KLF10/PTGS2/S1PR1/SNX10/ATRAID/LGR4/P2RX7/TGFB1/HIF1A/PTK2B/LEP/ROR2/FZD9/FGR/BMP2/LTBP3/TUFT1/ISG15/TRPM4/BMP7/BCOR/BMPR1A/BMP4/ADRB2/ASGR2/ZMPSTE24/KL/SRGN/CYP27B1/MINPP1/ERCC2/TGFB3/BMP2K/PTHLH/MGP/TMEM38B/IBSP/NBR1/TMEM119/FGF23/WNT10B/CER1/GJA1/GREM1/BMPR1B/MEF2C/BMPR2	52
BP	GO:0043403	skeletal muscle tissue regeneration	21/7096	41/18670	0.05822	0.1931	0.1439	IGF1/ANXA1/PPARD/EZH2/IFRD1/PKM/PTGFRN/MYOG/TARBP2/KLF5/MYOZ1/BIN3/CAPN3/FZD7/GPX1/DAG1/PAX7/WNT7A/WNT10B/GJA1/MYF6	21
BP	GO:0050434	positive regulation of viral transcription	21/7096	41/18670	0.05822	0.1931	0.1439	CHD1/TFAP4/TAF11/DHX9/GTF2F2/MDFIC/POLR2L/CTDP1/CDK9/POLR2H/SUPT4H1/RSF1/GTF2F1/POLR2F/POLR2D/POLR2K/NELFCD/HPN/CCNT1/POLR2I/NUCKS1	21
BP	GO:0006505	GPI anchor metabolic process	17/7096	32/18670	0.05865	0.1935	0.1443	PIGV/PIGP/PIGK/PIGN/PIGF/PIGB/DPM1/GPAA1/PIGM/MPPE1/PIGQ/PIGO/PIGH/DPM3/PIGT/PGAP3/PGAP1	17
BP	GO:0015012	heparan sulfate proteoglycan biosynthetic process	17/7096	32/18670	0.05865	0.1935	0.1443	HS3ST2/EXTL2/NDST2/HS2ST1/EXT2/EXT1/CSGALNACT1/XYLT1/B3GALT6/GLCE/XYLT2/NDST1/HS3ST1/HS3ST3B1/TCF7L2/B3GAT3/HS3ST6	17
BP	GO:0070207	protein homotrimerization	17/7096	32/18670	0.05865	0.1935	0.1443	ALOX5AP/SKI/DISP1/STEAP4/MIF/HTRA2/HSF4/HLA-G/ITLN1/MGST1/CD247/MLKL/TRAF2/CLYBL/ATXN10/SIGMAR1/PNPT1	17
BP	GO:0002115	store-operated calcium entry	12/7096	21/18670	0.05868	0.1935	0.1443	ORAI2/SARAF/STIM2/HOMER3/HOMER1/ORAI3/SPINK1/MS4A1/ORAI1/CASQ1/CD84/EFHB	12
BP	GO:0006907	pinocytosis	12/7096	21/18670	0.05868	0.1935	0.1443	APPL2/ACTN4/MAPKAPK3/AXL/NR1H2/EHD4/SNX33/DNM2/MAPKAPK2/NR1H3/SNX5/APPL1	12
BP	GO:0021697	cerebellar cortex formation	12/7096	21/18670	0.05868	0.1935	0.1443	DLL1/MAP2K1/LDB1/CDK5/OPHN1/CBLN1/RORA/FAIM2/ATP7A/KNDC1/WNT7A/AGTPBP1	12
BP	GO:0032682	negative regulation of chemokine production	12/7096	21/18670	0.05868	0.1935	0.1443	KLF4/ARG2/GSTP1/SOCS5/IL6/MEFV/LGALS9/MUL1/SIGIRR/MAP2K5/NR1H4/C1QTNF3	12
BP	GO:0035455	response to interferon-alpha	12/7096	21/18670	0.05868	0.1935	0.1443	LAMP3/IFNAR1/IFITM2/IFITM1/IFITM3/AXL/MX2/IFIT3/IFIT2/EIF2AK2/IFNAR2/ADAR	12
BP	GO:0071498	cellular response to fluid shear stress	12/7096	21/18670	0.05868	0.1935	0.1443	KLF4/KLF2/PTGS2/PKD2/SOCS5/PTK2B/MAPK7/SREBF2/NFE2L2/MAP2K5/MTSS1/MEF2C	12
BP	GO:1902884	positive regulation of response to oxidative stress	12/7096	21/18670	0.05868	0.1935	0.1443	SOD1/FBXW7/TNF/MCL1/TLR4/ACOX2/SFPQ/MIR34A/MMP3/ENDOG/TLR6/FOXO3	12
BP	GO:2000316	regulation of T-helper 17 type immune response	12/7096	21/18670	0.05868	0.1935	0.1443	NFKBIZ/IL27RA/NLRP3/SMAD7/ZBTB7B/NFKBID/IL12RB1/IL12B/TBX21/PRKCQ/MALT1/IL23A	12
BP	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	84/7096	192/18670	0.05872	0.1935	0.1443	IGF1/FYN/SOCS3/LYN/PARP9/FCGR1A/ENPP2/ITGA5/STAT3/LILRA5/TNFRSF14/NEDD9/BANK1/CD40/KITLG/MIF/FBXW7/CD44/JAK2/PTPRC/IL15/DVL2/TNF/CD74/GPRC5B/ERCC6/HCLS1/LRP8/TGFB1/HGF/CD36/PTK2B/LEP/NRG1/NCF1/FLT3/VEGFA/EHD4/ABL1/PAK2/CSPG4/PTK6/CCL5/ARHGEF2/SEMA4D/TNFRSF18/IL6ST/IL6/PDGFB/TAL1/HDAC2/NRP1/CLCF1/TEC/OSM/HES1/CNTF/IL18/ADAM17/TREM2/IL3/TSLP/IFNG/TNFSF18/HBEGF/CD4/LACRT/IL12B/RELN/CD80/CSF1R/MTOR/ARL2BP/LRP4/GHR/CD3E/GREM1/CD24/ERBB3/IL23A/CNTN1/GHRL/NTRK2/PTPRJ	84
BP	GO:0042509	regulation of tyrosine phosphorylation of STAT protein	39/7096	83/18670	0.05875	0.1935	0.1443	IGF1/FYN/SOCS3/LYN/PPP2CA/PARP9/STAT3/PTPN2/CD40/JAK2/IL15/TNF/HCLS1/LEP/FLT3/PTK6/CCL5/TNFRSF18/IL6ST/IL6/HDAC2/CLCF1/OSM/INPP5F/HES1/CNTF/CNOT7/IL18/SOCS1/IL3/TSLP/IFNG/TNFSF18/IL12B/CSF1R/ARL2BP/GHR/IL23A/MIR146A	39
BP	GO:1902807	negative regulation of cell cycle G1/S phase transition	59/7096	131/18670	0.05884	0.1938	0.1445	KLF4/CDKN2D/CDKN1A/GPNMB/ZNF655/RGCC/SLFN11/EZH2/PKD2/GIGYF2/BTG2/CDK4/CDKN2B/PLK2/SFN/PML/CDK2AP2/CCND1/ATM/TNKS1BP1/MUC1/CTDSPL/PLK3/NACC2/BCL2/PCNA/BAX/CRADD/CASP2/CTDSP1/RFWD3/CDKN1B/CDKN2C/CNOT4/FHL1/PLAGL1/ARID3A/BTN2A2/E2F4/CNOT7/GML/CTDSP2/MDM2/WEE1/RBL2/DCUN1D3/RB1/C10orf99/MEN1/CNOT10/CARM1/JADE1/TRIAP1/AURKA/CDC73/SOX4/PRMT1/E2F8/SUSD2	59
BP	GO:0097711	ciliary basal body-plasma membrane docking	44/7096	95/18670	0.05976	0.1967	0.1466	PRKAR2B/TUBA1A/NINL/TCTN1/RAB11A/ODF2/HAUS8/CNTRL/CEP164/PCM1/CSNK1D/CEP131/SFI1/PAFAH1B1/CDK5RAP2/CEP76/MAPRE1/B9D1/CSNK1E/TCTN2/HAUS2/NPHP4/KIF24/PRKACA/CKAP5/DCTN2/CEP152/TUBA4A/MKS1/CEP63/CEP57/CETN2/HAUS5/TUBB4A/HAUS1/YWHAE/CEP83/FGFR1OP/YWHAG/TCTN3/TTBK2/CEP78/C2CD3/ALMS1	44
BP	GO:0046902	regulation of mitochondrial membrane permeability	36/7096	76/18670	0.05991	0.1969	0.1468	BMF/SLC35F6/BLOC1S2/STAT3/PMAIP1/YWHAH/SLC9A1/TMEM14A/GSK3B/ALKBH7/MPV17L/FZD9/SFN/CASP8/RHOT2/CHCHD10/SLC25A5/BCL2L11/MAPK8/TMEM102/BCL2/BAX/GZMB/THEM4/YWHAQ/CAMK2A/MUL1/ACAA2/YWHAE/BAD/PPP1R13B/NAIF1/MOAP1/CNP/YWHAG/BAK1	36
BP	GO:1902653	secondary alcohol biosynthetic process	36/7096	76/18670	0.05991	0.1969	0.1468	POR/SOD1/NFYC/GPAM/SQLE/RAN/APOE/HMGCR/HMGCS1/SCD/ERLIN1/CNBP/ACLY/ERLIN2/FDPS/ACACB/G6PD/FGF1/ARV1/TM7SF2/APOA5/MSMO1/IDI1/SCAP/ABCG1/SC5D/SREBF2/CYB5R3/INSIG1/ACAA2/PRKAA1/APOA1/MBTPS2/ELOVL6/MBTPS1/KPNB1	36
BP	GO:0010921	regulation of phosphatase activity	77/7096	175/18670	0.05997	0.1969	0.1468	TSC1/PPP1R15A/CHP1/MGAT5/WDR81/JAK2/PTPRC/SHOC2/TNF/GSK3B/CABIN1/PPP4R2/PHACTR2/PPP2R3A/PHACTR1/PPP1R16A/PPP1R26/PPP6R1/SPOCD1/PPP1R14A/ELFN1/PPP1R37/BMP2/RCAN3/PPP1R2/SFI1/SLC39A10/PPP1R14B/CNST/SEMA4D/PPP1R15B/PPP1R16B/PPP2R5C/CD2BP2/ANKLE2/LMTK3/ZFYVE1/GNAI2/PPP2R2D/BOD1L1/PPP2R2B/ELFN2/PPP1R3B/RCAN1/ITGA2/CD300A/PPP4R1/PLEK/PPP1R36/ZCCHC9/PPP1R7/MYOZ1/SPRED1/PPP2R1B/EIF2AK2/PPP1R11/HSP90B1/SYTL2/IGBP1/LMTK2/IFNG/CHP2/MTMR9/MASTL/B3GAT3/PPP1R14D/HSP90AB1/PPP2R5B/PHACTR4/SET/CD33/MTOR/ROCK2/CCDC8/BOD1/PPP2R2C/MEF2C	77
BP	GO:0051341	regulation of oxidoreductase activity	49/7096	107/18670	0.05998	0.1969	0.1468	HTR2B/VDR/NOD2/ATP2B4/GCH1/POR/GNAI3/SIRT4/SCARB1/TNF/DDAH2/NFKB1/KRAS/APOE/HIF1A/PTK2B/LEP/ABL1/IL1B/GZMA/RFK/CHCHD10/GLA/LRRK2/SPR/FCER2/DNM2/GNAI2/OXA1L/CYBA/CNR2/PDP2/DHFR/EGFR/ABL2/CAV3/NUS1/CYP27B1/IFNG/ATP7A/HP/PDP1/TERT/CDH3/SNCA/ZDHHC21/FGF23/ECSIT/SLAMF8	49
BP	GO:0098781	ncRNA transcription	49/7096	107/18670	0.05998	0.1969	0.1468	ELL2/NABP1/SNAPC3/POU2F1/POU2F2/INTS5/GTF2E1/INTS7/SIRT7/TAF11/GTF2F2/INTS9/POLR2L/SNAPC1/TAF1B/SNAPC2/ELL3/CDK9/TAF5/RPRD1B/INTS8/POLR2H/RPRD2/CCNK/USPL1/GTF2F1/INTS3/POLR2F/POLR2D/PWP1/INTS2/GTF3A/IPPK/GTF2A1/POLR2K/GTF3C3/PHAX/RPAP2/CELF3/TBP/MTOR/CD3EAP/CCNT1/SNAPC4/SRRT/INTS4/ICE1/POLR2I/INTS6	49
BP	GO:0008089	anterograde axonal transport	24/7096	48/18670	0.06028	0.1975	0.1472	SOD1/BLOC1S2/KIF3B/HSPB1/AP3M2/TRAK2/DTNBP1/BLOC1S6/KIF4A/ARL8A/BLOC1S3/BLOC1S1/BLOC1S4/AP3B1/MAP1A/FMR1/KIF1B/AP3M1/KIF5B/TRAK1/KIF1C/MGARP/ARL8B/TRIM46	24
BP	GO:0009069	serine family amino acid metabolic process	24/7096	48/18670	0.06028	0.1975	0.1472	SEPHS2/GCLM/PSPH/AHCY/SEPSECS/SLC7A11/APIP/MTRR/GCLC/ENOPH1/DAO/SHMT2/TST/SERINC3/MPST/CTH/AHCYL2/AGXT2/SHMT1/AHCYL1/AMT/SRR/SLC25A32/PHGDH	24
BP	GO:0009311	oligosaccharide metabolic process	24/7096	48/18670	0.06028	0.1975	0.1472	HEXB/FBP1/MANBA/MGAM/MGAT2/GM2A/MAN2B1/ST3GAL2/GLA/IDUA/CTBS/NAGA/GAL3ST4/MAN1B1/ST8SIA4/MOGS/ST6GALNAC5/GAA/NEU1/ST6GALNAC6/B3GALT5/B4GALT1/MAN2B2/TREH	24
BP	GO:0061014	positive regulation of mRNA catabolic process	24/7096	48/18670	0.06028	0.1975	0.1472	ZFP36/TOB1/AGO2/YTHDF3/MOV10/HNRNPR/METTL14/GIGYF2/BTG2/METTL3/ZC3H12D/ZC3HAV1/FTO/GTPBP1/TNRC6B/TNRC6A/HNRNPD/CPEB3/CNOT7/ZFP36L2/PNPT1/ROCK2/PLEKHN1/UPF1	24
BP	GO:0030073	insulin secretion	90/7096	207/18670	0.06037	0.1976	0.1473	ANXA1/ACVR2B/PPARD/HADH/SIRT4/SMAD2/ENY2/PER2/CYB5R4/JAK2/FAM3D/TNF/HMGCR/DPP4/LRP5/PPP3CB/ITPR1/AACS/ARRB1/HIF1A/PIM3/ENHO/MYO5A/LEP/MCU/TCIRG1/IL1B/UQCC2/CCL5/C2CD2L/RAP1A/MPC2/LRP1/RAF1/RFX3/IL1RN/TRPM4/DOC2B/RAC1/GLUD1/IRS2/SLC25A5/KLF7/SERP1/SRI/OXCT1/RPH3AL/GPR27/SLC16A1/SYTL4/CPT1A/PDX1/TM7SF3/PTPRN2/PFKFB2/HMGN3/ICA1/CLOCK/GIPR/TCF7L2/BAD/SYT9/PLA2G6/HNF1B/IFNG/HNF1A/ARNTL/SNX19/KIF5B/STXBP3/NDUFAF2/MAP4K4/SLC9B2/SOX4/SIDT2/ARL2BP/RIMS2/GCG/PFKL/NLGN2/GJA1/NR1H4/TARDBP/STXBP4/PRKCA/UCN3/RBP4/PSMD9/GHRL/PHPT1	90
BP	GO:0099003	vesicle-mediated transport in synapse	90/7096	207/18670	0.06037	0.1976	0.1473	APBA1/ARF6/PINK1/STX11/DNM3/RAP1B/SYT11/BLOC1S2/RAB11A/POTEKP/FCHO2/DENND1A/P2RX7/CTBP2/GSK3B/ACTB/PPP3CB/STXBP1/UNC13B/SYNJ1/FBXL20/ITSN1/AP3M2/USP46/CDK5/OPHN1/RAB3GAP1/TMEM230/GRIP1/DTNBP1/NUMB/RAP1A/BLOC1S6/RAB8A/DOC2B/PREPL/LRRK2/SYT6/ARC/ADCY1/ARF1/DNAJC6/TOR1A/SH3GL1/DNM1/P2RX1/ADORA2B/VPS18/NAPA/DNM2/BLOC1S3/RAB5A/KIAA1107/CAMK2A/CANX/CHRM2/DNM1L/BLOC1S1/CHRNA4/BLOC1S4/AP3B1/ATP2A2/DVL1/PSEN1/FMR1/RAB3A/CHRNB2/P2RY4/PPFIA3/SYT9/AP3M1/SYT1/SYT2/VAMP1/DOC2A/SNAP29/SYT4/CADPS2/SYT5/SNCA/GSG1L/RIMS2/WNT7A/PICALM/NLGN2/KIAA1109/RAB27A/P2RY1/AMPH/TRIM46	90
BP	GO:0051924	regulation of calcium ion transport	109/7096	254/18670	0.06052	0.198	0.1476	SLC8A1/FYN/PTPN6/LILRB2/LYN/DIAPH1/TMBIM6/PTGS2/LILRA5/LILRA2/CXCL9/CXCL11/P2RX7/SLC9A1/CXCL10/PKD2/LILRB1/CXCL12/TGFB1/KCNE3/WFS1/PTK2B/MYO5A/CORO1A/P2RY6/AHNAK/SARAF/PDE4B/ABL1/STIM2/GSTO1/HOMER3/CCL5/PLCG2/PML/P2RY12/DMD/HOMER1/TMC2/PDGFB/G6PD/IL16/SPINK1/SUMO1/PSEN2/SRI/MIR34A/P2RX1/BCL2/GNAI2/BAX/INPP5K/ATP1B1/PRKACA/LPAR3/CYBA/CAMK2A/F2R/MYLK/CAMK2D/CEMIP/ORAI1/CAV3/ANXA2P2/STAC2/FMR1/GPR35/YWHAE/EPB41/CASQ1/PLA2G6/CD84/CAPN3/CASQ2/HRC/EFHB/BDKRB1/OPRD1/CD4/EHD3/TMEM38B/LACRT/PIK3CG/CACNB3/REM2/CD33/OPRL1/ANXA2/LIME1/RHOA/SNCA/CX3CL1/P2RX2/SLN/BAK1/GCG/CCL4/TMC1/KCNE2/ATP1A2/GJA1/ADCYAP1R1/TRPV3/BIN1/TRPV2/NTSR1/PACSIN3/CAMK2B/P2RX5	109
BP	GO:0051101	regulation of DNA binding	56/7096	124/18670	0.06115	0.1999	0.149	KLF4/IGF1/MAD2L2/SKI/DDRGK1/CEBPG/FBXW7/PER2/JAK2/NFKBIA/HMOX1/ERCC4/DOT1L/ZBTB7A/TGFB1/SIN3A/ENHO/TRAF6/NSD1/TFAP4/HABP4/SP100/GZMA/AGER/ZNF593/CSNK2B/HMGB1/HEY1/PLAUR/SUMO1/SRI/HDAC2/MAPK8/MMP9/HMGB2/ID2/NME1/ITGA2/ZFP90/RSF1/PDX1/HES1/ZMPSTE24/TXN/HEY2/CPNE1/PSEN1/ACD/ERCC2/IFNG/RB1/MSX1/EDF1/TRIM6/PAX7/SMO	56
BP	GO:0001541	ovarian follicle development	27/7096	55/18670	0.06118	0.1999	0.149	SOD1/KITLG/LFNG/CEBPB/UBE3A/ARRB1/CTNNA1/ZNF830/PTX3/EIF2B5/VEGFA/ATM/IMMP2L/BCL2/BAX/INHBA/HYAL3/MMP14/FANCG/TAF4/FSHR/INHA/KMT2B/EIF2B2/BMPR1B/MMP19/FOXO3	27
BP	GO:0010676	positive regulation of cellular carbohydrate metabolic process	30/7096	62/18670	0.06127	0.1999	0.149	IGF1/PTPN2/PMAIP1/SLC45A3/KAT2B/DYRK2/PTAFR/PPP1R3E/INSR/P2RY6/DDB1/SIRT1/DGAT2/IRS2/DUSP12/PPARGC1A/SLC25A12/PFKFB1/PFKFB2/PPARA/KAT2A/BAD/ESRRB/SNCA/CD244/GCG/ADCYAP1R1/WDR5/P2RY1/NTSR1	30
BP	GO:0048857	neural nucleus development	30/7096	62/18670	0.06127	0.1999	0.149	MBP/YWHAH/NDRG2/ACTB/RAD1/ZNF148/NDUFS3/HSPA5/CASP5/BASP1/GLUD1/TTBK1/SUDS3/G6PD/ARX/BCL2/YWHAQ/GNB4/CDK5R2/HOXB1/MAOB/SYNGR3/CHRNB2/YWHAE/SYPL2/INA/MAPKAP1/CNP/RHOA/PLP1	30
BP	GO:1905818	regulation of chromosome separation	30/7096	62/18670	0.06127	0.1999	0.149	DUSP1/MAD2L2/DYNC1LI1/SPDL1/CSNK2A2/CENPE/KLHL22/CDK5RAP2/NSMCE2/CDC23/ESPL1/ZNF207/LCMT1/ATM/ANAPC5/BUB3/NDC80/GEN1/ZW10/MOS/CDC26/RIOK2/DLGAP5/ANAPC4/CDC27/CDC20/PCID2/RB1/ANAPC11/IK	30
BP	GO:0009791	post-embryonic development	41/7096	88/18670	0.06144	0.2001	0.1491	KLF4/CSRNP1/ACVR2B/NR4A2/PLEKHA1/SMAD2/ATF5/AGO2/IMPAD1/GIGYF2/ITPR1/SGPL1/HEG1/VEGFA/ABL1/IGF2R/CHST11/ACO1/ALDH5A1/SERP1/ATM/BCL2L11/CYP1A2/ASH1L/BCL2/BMP4/BAX/TIPARP/ERCC1/KDM5B/FZD5/IREB2/BCL11B/PSEN1/RAB3A/ERCC2/MTOR/SCN9A/MFAP2/BAK1/INPPL1	41
BP	GO:0034103	regulation of tissue remodeling	41/7096	88/18670	0.06144	0.2001	0.1491	VDR/SIGLEC15/PDK4/CSK/GPNMB/ATP6AP1/SPP1/TNFAIP3/S1PR1/IL15/P2RX7/ADAM8/CST3/TGFB1/LEP/ABR/LTBP3/AGER/TNFRSF11A/PLEKHM1/IL6/BCR/MIR34A/TMEM64/BAX/SUCO/EGFR/IL18/TFRC/DCSTAMP/HRG/CLDN18/IL12B/CSF1R/IAPP/ROCK2/TMEM119/GJA1/GREM1/PRKCA/IL23A	41
BP	GO:0061097	regulation of protein tyrosine kinase activity	41/7096	88/18670	0.06144	0.2001	0.1491	FYN/FCGR1A/PTPN2/LILRA5/NEDD9/FBXW7/PTPRC/DVL2/GPRC5B/ERCC6/LRP8/CBLB/SOCS5/ZFYVE28/RAP2C/NRG1/ZGPAT/HYAL2/NCF1/PAK2/RAP2B/MVP/PTK6/CCL5/SHC1/SH3BP5L/PDGFB/TAL1/SNX6/TSG101/VPS25/ADAM17/PSEN1/FGFR1OP/RELN/CSF1R/APP/CD24/ERBB3/GHRL/NTRK2	41
BP	GO:0106027	neuron projection organization	41/7096	88/18670	0.06144	0.2001	0.1491	FYN/SIPA1L1/DNM3/LGMN/DOCK10/EPHB2/APOE/GSK3B/ACTR2/LRP8/UBE3A/INSR/BAIAP2/IGF1R/CDK5/PAFAH1B1/HOMER1/CAPRIN1/KALRN/LRRK2/ARC/ARF1/PDLIM5/CFL1/MTMR2/SHANK1/ITGA3/BHLHB9/DNM1L/DVL1/MAP1A/PSEN1/EPHB1/RELN/PICK1/APP/ABCD1/WNT7A/SHANK3/ZMYND8/CAMK2B	41
BP	GO:0090174	organelle membrane fusion	46/7096	100/18670	0.06197	0.2016	0.1503	ANXA1/STX7/STX11/GNAI3/TAP2/TAP1/SEC22B/SAMD9L/C2CD5/VPS41/STXBP1/CORO1A/VAMP3/SAMD9/RAB20/ANKRD27/BET1/RAB8A/DOC2B/GOSR2/GOSR1/TAPBP/STX5/SPHK1/VPS18/STX16/NKD2/VTI1A/RAB7B/CALR/RAB8B/ANXA2P2/RAB3A/STX12/VTI1B/SYT9/STX8/SYT1/KIF5B/VPS16/VAMP1/SNAP29/SYT4/ANXA2/SNCA/VPS8	46
BP	GO:0120034	positive regulation of plasma membrane bounded cell projection assembly	46/7096	100/18670	0.06197	0.2016	0.1503	CDC42EP4/RAC2/DPYSL3/DNM3/ARAP1/P2RX7/KCTD17/TWF2/PLEK2/PFN1/CDC42EP2/SRF/FUZ/HRAS/FAM98A/P2RY12/RAC1/PLEKHM1/CCDC88A/CDC42EP3/CYFIP1/BBS4/NRP1/DNM2/BCAS3/HDAC4/RHOQ/NDEL1/DOCK11/FSCN1/WNT1/FMR1/TGFB3/ATP7A/MIEN1/ARPC2/EPS8L2/CEP120/MTOR/CCL19/CCR7/TENM2/RP1/NCKAP1/WRAP73/ZMYND8	46
BP	GO:0001573	ganglioside metabolic process	11/7096	19/18670	0.06248	0.2016	0.1503	HEXB/GM2A/B4GALT6/B4GALNT1/CLN6/B4GALT5/ST8SIA4/NEU1/ST6GALNAC3/ST6GALNAC6/ST3GAL5	11
BP	GO:0002544	chronic inflammatory response	11/7096	19/18670	0.06248	0.2016	0.1503	S100A8/TNFAIP3/AHCY/TNF/CXCL13/IDO1/CCL5/VNN1/ADORA2B/UNC13D/GJA1	11
BP	GO:0006044	N-acetylglucosamine metabolic process	11/7096	19/18670	0.06248	0.2016	0.1503	NANP/EXTL2/GNPDA1/NAGK/CHST2/RENBP/CHST5/GNPNAT1/MGAT3/GNE/CHST7	11
BP	GO:0009148	pyrimidine nucleoside triphosphate biosynthetic process	11/7096	19/18670	0.06248	0.2016	0.1503	CTPS2/CMPK2/NME3/NME4/NME1/TYMS/UCK1/TBPL1/CTPS1/CAD/UCKL1	11
BP	GO:0010888	negative regulation of lipid storage	11/7096	19/18670	0.06248	0.2016	0.1503	PTPN2/PPARD/TNF/NFKBIA/LEP/NR1H2/ABCA1/IL6/ABCG1/NR1H3/PPARA	11
BP	GO:0034312	diol biosynthetic process	11/7096	19/18670	0.06248	0.2016	0.1503	ASAH1/GCH1/PCBD1/SPTLC2/QDPR/PTS/SPR/SPHK1/DHFR/ACER3/PCBD2	11
BP	GO:0045076	regulation of interleukin-2 biosynthetic process	11/7096	19/18670	0.06248	0.2016	0.1503	CLEC7A/ZFP36/PTPRC/IL1B/GLMN/IL1A/LAG3/CD4/CD80/PRKCQ/CD3E	11
BP	GO:0046112	nucleobase biosynthetic process	11/7096	19/18670	0.06248	0.2016	0.1503	GMPS/PAICS/CTPS2/CMPK1/PRPS1/PPAT/ADA/SHMT1/CTPS1/CAD/MTOR	11
BP	GO:0048025	negative regulation of mRNA splicing, via spliceosome	11/7096	19/18670	0.06248	0.2016	0.1503	RNPS1/RBM42/SRSF10/HNRNPK/HNRNPA2B1/SFSWAP/SRSF6/SRSF7/C1QBP/SRSF4/SAP18	11
BP	GO:0070989	oxidative demethylation	11/7096	19/18670	0.06248	0.2016	0.1503	JMJD6/ALKBH1/TET2/ALKBH4/TDG/CYP2D6/FTO/CYP1A2/ALKBH2/CYP2C8/TET1	11
BP	GO:0071071	regulation of phospholipid biosynthetic process	11/7096	19/18670	0.06248	0.2016	0.1503	FPR2/HTR2B/SLC27A1/CAPN2/IDH1/FABP3/PDGFB/RAB38/PDGFA/LPCAT1/NR1H4	11
BP	GO:0071243	cellular response to arsenic-containing substance	11/7096	19/18670	0.06248	0.2016	0.1503	HMOX1/ATF4/ZFAND2A/MAPK13/HNRNPA1/GSTO1/DDX3X/MKNK2/VCP/DAXX/CPEB2	11
BP	GO:0071731	response to nitric oxide	11/7096	19/18670	0.06248	0.2016	0.1503	AIFM1/MTR/EGLN1/CRK/DNM2/MMP3/HNRNPD/TRAF2/CCNA2/CCL19/CCR7	11
BP	GO:0071800	podosome assembly	11/7096	19/18670	0.06248	0.2016	0.1503	HCK/TNF/KIF9/ARHGEF2/BIN2/LCP1/FSCN1/MSN/RHOA/ASAP1/MAPK9	11
BP	GO:1900409	positive regulation of cellular response to oxidative stress	11/7096	19/18670	0.06248	0.2016	0.1503	SOD1/FBXW7/TNF/MCL1/TLR4/SFPQ/MIR34A/MMP3/ENDOG/TLR6/FOXO3	11
BP	GO:1902170	cellular response to reactive nitrogen species	11/7096	19/18670	0.06248	0.2016	0.1503	AIFM1/STAT6/MTR/CRK/PPARGC1A/DNM2/MMP3/HNRNPD/MAP3K5/TRAF2/CCNA2	11
BP	GO:0045911	positive regulation of DNA recombination	20/7096	39/18670	0.06282	0.2026	0.1511	MAD2L2/STAT6/CD40/PTPRC/ACTR2/TGFB1/MLH1/FUS/CLCF1/TIMELESS/TFRC/TNFSF4/ERCC2/EXOSC3/TBX21/EXOSC6/WAS/PAXIP1/ATAD5/UBE2B	20
BP	GO:0001844	protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	16/7096	30/18670	0.0632	0.2033	0.1516	BMF/PMAIP1/YWHAH/SFN/CASP8/BCL2L11/MAPK8/BCL2/BAX/GZMB/YWHAQ/YWHAE/BAD/PPP1R13B/MOAP1/YWHAG	16
BP	GO:0021696	cerebellar cortex morphogenesis	16/7096	30/18670	0.0632	0.2033	0.1516	DLL1/MAP2K1/LDB1/CDK5/OPHN1/CBLN1/RORA/FAIM2/ATP7A/SPTBN2/KNDC1/TRNP1/WNT7A/AGTPBP1/SMO/KIF14	16
BP	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	16/7096	30/18670	0.0632	0.2033	0.1516	LAMP1/CD226/HLA-F/HLA-E/RASGRP1/PVR/LAG3/ULBP2/CRTAM/VAV1/AP1G1/NCR3/IL12B/SH2D1A/MICA/IL18RAP	16
BP	GO:0061842	microtubule organizing center localization	16/7096	30/18670	0.0632	0.2033	0.1516	EZR/SUN2/FHOD1/BICD2/PAFAH1B1/ASPM/SYNE2/NDEL1/GPSM2/IFT20/CEP83/KIF5B/PLXNA2/DYNC1LI2/MISP/AURKA	16
BP	GO:1902751	positive regulation of cell cycle G2/M phase transition	16/7096	30/18670	0.0632	0.2033	0.1516	RAB11A/CDK4/SIN3A/MTA3/DBF4B/NPM1/RAD51B/CCND1/CDC25A/VPS4B/DTL/DYRK3/RCC2/APP/ATAD5/WNT10B	16
BP	GO:0048863	stem cell differentiation	110/7096	257/18670	0.06379	0.2051	0.1529	HTR2B/FN1/RBPJ/STAT3/SEMA4B/PSMB9/KLHL12/PSMB8/KITLG/RDH10/CBFB/PTPRC/LDB1/A2M/PSMA5/BATF/PSMD11/ZEB2/PSME1/LMO2/HIF1A/PSMB10/PSMA1/PSMA4/CHD2/ZNF281/SRF/METTL3/NRG1/SEMA4A/SOX21/TCF12/ABL1/PSMB1/PSMC4/LTBP3/XRCC5/SEMA4C/SEMA4D/PSMD13/EFNB1/PSMB3/BMP7/ELL3/TAL1/NOLC1/PSMB5/PSMD6/SEMA6B/PSMC3/KBTBD8/N4BP2L2/BMPR1A/NRP1/PSME3/SEMA3B/ANXA6/DNMT3L/BMP4/SETD6/PSMC6/NRP2/CFL1/OSM/PDX1/PEF1/TEAD2/FOXO4/SEMA5A/HES1/CORO1C/FZD1/NFE2L2/PWP1/EIF2AK2/SEMA5B/MAPK1/PSMC1/ERCC2/ZFP36L2/HNF1B/PSMD8/PSMA2/RET/MSI2/PHACTR4/TACSTD2/SOX5/MSX1/PSMC5/TRIM6/ESRRB/FBXL17/PSMC2/PSMB2/PSMD4/WNT10A/PUS7/PSMD1/WNT7A/SHC4/PSMB4/GREM1/SMO/LBH/HOXA7/PSMD9/PSMD3/MEF2C/MIR146A	110
BP	GO:0072395	signal transduction involved in cell cycle checkpoint	35/7096	74/18670	0.06431	0.2067	0.1541	CDKN1A/RGCC/BTG2/UIMC1/PLK2/SFN/PML/ATM/TNKS1BP1/MUC1/PLK3/PCNA/BAX/CRADD/CASP2/CDKN1B/CNOT4/PLAGL1/ARID3A/DTL/E2F4/BRCA1/CNOT7/GML/MDM2/RBL2/CNOT10/PRPF19/CARM1/TRIAP1/AURKA/SOX4/BRCC3/PRMT1/E2F8	35
BP	GO:0010810	regulation of cell-substrate adhesion	93/7096	215/18670	0.06456	0.2073	0.1545	MYADM/S100A10/FN1/RAC2/BST1/TSC1/GBP1/ITGA5/BCL6/NEDD9/FLNA/CIB1/ACTN4/JAK2/LDB1/SLC9A1/GSK3B/PTPRO/DUSP3/PEAK1/CD36/PTK2B/ADAM15/NINJ1/VEGFA/ABL1/MMP12/LRP1/CRK/PPM1F/SLK/RAC1/DOCK5/RELL2/PTK2/ARHGAP6/EMILIN3/LIMCH1/EMP2/NRP1/DISC1/BCL2/DNM2/WDPCP/SERPINE1/BCAS3/UNC13D/KANK1/TRIOBP/LGALS1/SPOCK2/ITGA3/MMP14/DMTN/CORO1C/CALR/ATXN3/CLASP2/C1QBP/RCC2/FZD4/PREX1/WNT1/EMID1/APOA1/SKAP1/SPOCK1/HRG/GCNT2/FZD7/TACSTD2/MEN1/NID1/ARPC2/PRKCZ/MAP4K4/RHOA/LIMS1/DAG1/CX3CL1/ITGB1BP1/FOXF1/CCR7/CD3E/EMILIN2/ROCK2/ATXN3L/HOXA7/MACF1/HSD17B12/PIK3CB/PTPRJ/FMN1	93
BP	GO:0070374	positive regulation of ERK1 and ERK2 cascade	93/7096	215/18670	0.06456	0.2073	0.1545	FPR2/HTR2B/NOD2/GLIPR2/NOTCH2/GPNMB/ATP6AP1/RAP1B/FLT1/MARCO/MIF/MAP2K1/CIB1/FBXW7/ACKR3/CD44/PTPRC/TNF/CD74/APOE/HMGCR/SLAMF1/TGFB1/ARRB1/RAPGEF2/CD36/PTK2B/P2RY6/TLR4/PTPN22/FLT3/PDGFC/BMP2/HRAS/ABL1/AGER/CCL5/MAP3K12/RASGRP1/RAP1A/SHC1/LRP1/HMGB1/TNFRSF11A/CCL7/NPTN/MFHAS1/CHI3L1/PDGFB/CCL13/NRP1/PRKD2/GNAI2/CCL8/BMP4/FFAR4/LGALS9/PDGFA/F2R/ABCA7/EGFR/CCL20/CCL26/SPRY2/HCRTR1/TREM2/HAVCR2/GCNT2/CD4/FSHR/PRKCZ/CSF1R/TRPV4/C5AR2/PDE8A/APP/GPR183/CX3CL1/CCL19/TIRAP/SLC30A10/GCG/CCL4/CCR7/FGF23/IL26/CCL24/HMGB4/PRKCA/SERPINF2/P2RY1/PDGFD/THPO	93
BP	GO:0009410	response to xenobiotic stimulus	124/7096	292/18670	0.06481	0.208	0.1551	CRHBP/NQO1/EPHX1/SLC8A1/S100A12/PEA15/PRKAR2B/ATG7/NR4A2/POR/FOSB/CMBL/SOD1/SRD5A1/ACAA1/RGS2/MGST2/GSTP1/EGR1/PRKACB/HNMT/AHRR/AKR7A2/RELA/UBE3A/TGFB1/CYP1B1/AKR7A3/PTAFR/MAP1LC3A/PTK2B/PCK2/CYB5B/MBD1/TFAP4/CYP2J2/RYR1/HSPA5/AKR1C1/CDK5/CYP2S1/GCLC/STAT5A/GSTO1/AIF1/AHR/CES2/GSTA1/HOMER1/PDGFB/GSTM3/SMYD3/PPARGC1A/PTGES3/ARNT2/BPHL/SCGB1A1/HDAC2/MGST1/CYP2D6/CYP1A2/CBR3/DNM2/PCNA/CYP26B1/TIPARP/GSTM5/GSS/AS3MT/ABCB4/RHBDD3/PITX3/DDIT4/CNR2/GSTM4/CYB5R3/GOT2/ADA/ARNT/EGFR/FADD/DNMT3A/CES3/PRKAA1/MGST3/MDM2/CHRNB2/SRR/RORA/CASQ2/CAD/EIF4E/SMPD1/NAT2/TMEM38B/HSP90AB1/RB1/CCNA2/SULT1B1/DBH/CYP26A1/GPX1/MARC2/MTOR/HDAC5/FMO2/SNCA/NAT1/CRYZ/CYP2W1/GHR/RGS17/CYP2A6/EFTUD2/CYP46A1/PHGDH/ALDH3A1/CYP2C8/TDO2/HTR3A/PTGS1/FOXO3/CYP2U1/AIP	124
BP	GO:0010883	regulation of lipid storage	23/7096	46/18670	0.06503	0.2082	0.1552	PTPN2/PPARD/FBXW7/SCARB1/TNF/NFKBIA/NFKB1/ALKBH7/CD36/LEP/NR1H2/ABCA1/ACACB/EHD1/SIRT1/IL6/FTO/ABCG1/NR1H3/SREBF2/MEST/PPARA/VSTM2A	23
BP	GO:0022602	ovulation cycle process	23/7096	46/18670	0.06503	0.2082	0.1552	RETN/PLEKHA1/ARRB1/SGPL1/ZNF830/LEP/PTX3/HSPA5/CASP3/SIRT1/PAM/CASP2/INHBA/FZD4/SLIT2/TGFB3/FSHR/NRIP1/BMPR1B/MMP19/FOXO3/KISS1/SLIT3	23
BP	GO:0032527	protein exit from endoplasmic reticulum	23/7096	46/18670	0.06503	0.2082	0.1552	BCAP31/TMEM129/EDEM1/SAR1B/SEC61B/UBE2J1/UBE2G2/EDEM2/SAR1A/NPLOC4/DERL1/RANGRF/DERL2/INSIG1/YOD1/HSP90B1/TMEM30A/VCP/TM9SF4/PREB/ERLEC1/OS9/SEC16B	23
BP	GO:0035196	production of miRNAs involved in gene silencing by miRNA	23/7096	46/18670	0.06503	0.2082	0.1552	MAP2K1/SMAD2/AGO2/TGFB1/METTL3/BCDIN3D/HNRNPA2B1/MRPL44/PUM2/SNIP1/DICER1/NCOR1/TARBP2/BMP4/AGO1/MAP2K2/ZMPSTE24/EGFR/ZC3H7B/ZC3H10/DROSHA/ADAR/SRRT	23
BP	GO:1900015	regulation of cytokine production involved in inflammatory response	23/7096	46/18670	0.06503	0.2082	0.1552	MYD88/NOD2/IL1R2/CLEC7A/APPL2/IL17RA/GBP5/TICAM1/CHID1/LEP/TLR4/C5orf30/ADCY7/GPSM3/MEFV/IL17B/BAP1/PDCD4/ABCD1/APPL1/NLRC3/TLR6/IL17RC	23
BP	GO:0072503	cellular divalent inorganic cation homeostasis	204/7096	493/18670	0.06528	0.2089	0.1557	SLC8A1/S100A9/S100A8/FPR2/HTR2B/VDR/FPR1/CCR2/FYN/CX3CR1/PTGER4/PTPN6/S1PR4/HEXB/ATP2B4/LYN/CD55/SLC11A1/WNT5A/MCOLN1/S1PR3/PTGER2/TPCN1/DIAPH1/TMBIM6/GNB1/S1PR1/CD40/GNA15/ACKR3/P2RY8/CXCL9/JAK2/CXCL11/PTPRC/P2RX7/BCAP31/KCTD17/CXCL10/PKD2/APOE/CXCL12/ATF4/TGFB1/ITPR1/FIS1/WFS1/CD36/LPAR2/PTK2B/MYO5A/SWAP70/CORO1A/P2RY6/MCU/CXCL13/TCIRG1/RYR1/FZD9/CDK5/ABL1/SLC39A10/CMKLR1/STIM2/GSTO1/CLN3/CCL5/PLCG2/PML/CYSLTR1/ATP2C1/LRP1/HMGB1/SLC39A8/DMD/VAPB/CCL7/TRPM4/NPTN/ATP7B/AFG3L2/TRPM2/SLC39A13/PDZD8/LPAR6/CXCR1/LCK/CDH5/CCR5/SLC39A7/SRI/RASA3/C3AR1/CCL13/TMEM64/P2RX1/NMUR2/DISC1/ANXA6/BCL2/CCL8/TGM2/BAX/ATP1B1/MS4A1/CHRNA10/CCR6/PRKACA/LPAR3/GPR18/CXCR6/CCR4/CYBA/MICU1/LPAR1/MCOLN2/ATP13A5/PROK2/SLC39A12/F2R/GRIN2C/CALR/SLC41A1/SLC35G1/CAMK2D/PLCB1/CCR3/CEMIP/CXCR2/ABL2/NMB/CAV3/ATP2A2/HSP90B1/ANXA2P2/LETM1/SLC8A2/GIPR/TACR1/PSEN1/GNA13/GPR35/GALR1/P2RY4/HCRTR1/YWHAE/SYPL2/CASQ1/PLA2G6/SLC24A4/CAPN3/CASQ2/HRC/SLC30A2/BDKRB1/GPR12/PKHD1/CD4/TMEM38B/LACRT/PIK3CG/CACNB3/OPRL1/ANXA2/LIME1/P2RY10/TRPV4/C5AR2/APP/GPR6/SNCA/CX3CL1/IAPP/CXCR3/P2RX2/SLC24A2/CIB2/CCL19/CCKBR/BAK1/CHERP/GCM2/SLC30A9/ATP1A2/CCR7/SLC8A3/MCOLN3/FAM155A/GJA1/ACKR2/GPR20/ADCYAP1R1/CCRL2/CD24/KEL/P2RY1/NTSR1/MICU2/GHRL/KISS1/PIK3CB/P2RX5/SYNPO/GTF2I	204
BP	GO:0007260	tyrosine phosphorylation of STAT protein	40/7096	86/18670	0.06579	0.2095	0.1562	IGF1/FYN/SOCS3/LYN/PPP2CA/PARP9/STAT3/PTPN2/CD40/JAK2/IL15/TNF/HCLS1/LEP/FLT3/PTK6/CCL5/TNFRSF18/IL6ST/IL6/HDAC2/CLCF1/OSM/INPP5F/FER/HES1/CNTF/CNOT7/IL18/SOCS1/IL3/TSLP/IFNG/TNFSF18/IL12B/CSF1R/ARL2BP/GHR/IL23A/MIR146A	40
BP	GO:0070542	response to fatty acid	40/7096	86/18670	0.06579	0.2095	0.1562	TLR2/PTGER4/PDK4/PTGER2/PTGS2/GNB1/HMGCL/AKR1C3/CDK4/AACS/ALAD/PTAFR/FFAR2/SCD/CD36/P2RY6/CAT/XRCC5/LDLR/CREB1/DGAT2/FABP3/GNG2/PPARGC1A/AKAP8/YY1/NME1/CPT1A/PDX1/UCP1/TNFSF4/GIPR/PRKAA1/PID1/P2RY4/BAD/GNPAT/CCL19/CCR7/NR1H4	40
BP	GO:0090559	regulation of membrane permeability	40/7096	86/18670	0.06579	0.2095	0.1562	BMF/SLC35F6/BLOC1S2/STAT3/PMAIP1/YWHAH/F11R/SLC9A1/TMEM14A/GSK3B/ALKBH7/HEG1/MPV17L/FZD9/SFN/CASP8/RHOT2/CHCHD10/SLC25A5/BCL2L11/MAPK8/TMEM102/BCL2/BAX/GZMB/THEM4/YWHAQ/CAMK2A/LAPTM4B/MUL1/ACAA2/YWHAE/BAD/PPP1R13B/NAIF1/MOAP1/CNP/YWHAG/MTOR/BAK1	40
BP	GO:0032508	DNA duplex unwinding	50/7096	110/18670	0.0659	0.2095	0.1562	ANXA1/ASCC3/MCM6/GINS1/MCM2/RAD23B/CHD1/ERCC6/RPA1/CHD2/RUVBL2/RUVBL1/DDB1/PURA/WRNIP1/DSCC1/XRCC5/HMGA1/CHD9/DHX9/GTF2F2/SMARCAD1/RFC3/DDX3X/SETX/GTF2H4/ACTR5/CHD6/RAD54B/DDX1/UBC/RECQL/ERCC6L/GINS4/CETN2/MCM5/RTEL1/DDB2/SUPV3L1/ERCC2/XRCC6/CUL4B/NAV2/MCM8/POT1/RBX1/RECQL4/ZRANB3/TOP2A/ERCC8	50
BP	GO:0033559	unsaturated fatty acid metabolic process	50/7096	110/18670	0.0659	0.2095	0.1562	ALOX5/ANXA1/ALOX5AP/PTGS2/ACAA1/MIF/PTGR1/GSTP1/MGLL/DEGS1/CD74/ELOVL5/SCP2/AKR1C3/PLAA/ZADH2/PTGR2/CYP1B1/SCD/HPGD/CYP2J2/FADS3/CYP2S1/IL1B/ACOX1/HSD17B4/CES2/GSTA1/ELOVL7/SIRT1/DECR2/PNPLA8/PTGES3/ALOX15B/DAGLB/CYP2D6/CYP1A2/HPGDS/FABP5/ELOVL6/ATP6V1B1/CYP4F3/ABCD1/ABHD16A/CYP2A6/CYP2C8/FADS2/PTGS1/CYP2U1/ACOT8	50
BP	GO:0000186	activation of MAPKK activity	26/7096	53/18670	0.06594	0.2095	0.1562	JAK2/MAP3K8/ERCC6/MAP3K4/TAOK3/GADD45B/MAP3K12/CRK/RAF1/LRRK2/BMP4/MAP3K6/MLKL/MAP3K11/MAP3K5/F2R/MOS/EIF2AK2/EGFR/ADAM9/PSEN1/MAPK1/MAP3K13/MAP3K1/NRK/MAP3K9	26
BP	GO:0045744	negative regulation of G protein-coupled receptor signaling pathway	26/7096	53/18670	0.06594	0.2095	0.1562	HTR2B/ATP2B4/STMN1/RGS2/ARRDC3/ARRB1/CCL5/KLK14/BICD1/DNM1/RPH3AL/UBQLN2/DNM2/GNAI2/RGS14/ADRB2/PLEK/ADA/GPRASP1/GIPR/GRK4/RGS13/OPRL1/SNCA/MET/APLN	26
BP	GO:1903307	positive regulation of regulated secretory pathway	26/7096	53/18670	0.06594	0.2095	0.1562	ITGAM/IL4R/LAMP1/STXBP1/UNC13B/PTAFR/HLA-F/FGR/CDK5/DOC2B/ARF1/ADORA2B/UNC13D/HYAL3/DNM1L/CDK5R2/AP1G1/RAB3A/SYT9/SYT1/SNX4/SYT4/SCAMP5/RAB3D/CACNA1H/RAB27A	26
BP	GO:0051306	mitotic sister chromatid separation	29/7096	60/18670	0.06595	0.2095	0.1562	DUSP1/MAD2L2/DYNC1LI1/SPDL1/CENPE/KLHL22/CDK5RAP2/NSMCE2/CDC23/ESPL1/ZNF207/LCMT1/ATM/ANAPC5/BUB3/NDC80/GEN1/ZW10/CDC26/RIOK2/DLGAP5/ANAPC4/DIS3L2/CDC27/CDC20/PCID2/RB1/ANAPC11/IK	29
BP	GO:1902110	positive regulation of mitochondrial membrane permeability involved in apoptotic process	29/7096	60/18670	0.06595	0.2095	0.1562	BMF/SLC35F6/BLOC1S2/PMAIP1/YWHAH/TMEM14A/GSK3B/MPV17L/FZD9/SFN/CASP8/RHOT2/CHCHD10/SLC25A5/BCL2L11/MAPK8/TMEM102/BCL2/BAX/GZMB/YWHAQ/MUL1/ACAA2/YWHAE/BAD/PPP1R13B/MOAP1/YWHAG/BAK1	29
BP	GO:0000963	mitochondrial RNA processing	10/7096	17/18670	0.06636	0.2095	0.1562	TRMT5/TRMT61B/PUS1/HSD17B10/TBRG4/SUPV3L1/MTO1/PNPT1/TRMT10C/FASTKD5	10
BP	GO:0002693	positive regulation of cellular extravasation	10/7096	17/18670	0.06636	0.2095	0.1562	CCR2/ADAM8/PTAFR/ITGA4/CD99/AGER/IL1R1/CD99L2/FADD/PDGFD	10
BP	GO:0006089	lactate metabolic process	10/7096	17/18670	0.06636	0.2095	0.1562	LDHA/PER2/MRS2/HIF1A/PNKD/HAGH/LDHB/SLC25A12/LDHC/PFKFB2	10
BP	GO:0006577	amino-acid betaine metabolic process	10/7096	17/18670	0.06636	0.2095	0.1562	SLC22A4/POR/ALDH9A1/ALDH7A1/ACADM/BHMT/CPT1A/SHMT1/CROT/CHDH	10
BP	GO:0006883	cellular sodium ion homeostasis	10/7096	17/18670	0.06636	0.2095	0.1562	SLC8A1/ATP1A1/SLC9A1/ATP4A/ATP1B2/ATP1B3/ATP1B1/ATP1A2/ATP12A/C7	10
BP	GO:0016246	RNA interference	10/7096	17/18670	0.06636	0.2095	0.1562	AGO2/TSN/DHX9/MRPL44/CLP1/DICER1/TARBP2/DROSHA/TERT/ADAR	10
BP	GO:0031649	heat generation	10/7096	17/18670	0.06636	0.2095	0.1562	SLC27A1/PTGS2/TNF/ARRDC3/ADRB1/IL1B/TNFRSF11A/IL1A/ADRB2/APLN	10
BP	GO:0035729	cellular response to hepatocyte growth factor stimulus	10/7096	17/18670	0.06636	0.2095	0.1562	APPL2/GCLM/LGMN/RELA/HGF/GCLC/CREB1/ADAMTS12/NRP1/APPL1	10
BP	GO:0043373	CD4-positive, alpha-beta T cell lineage commitment	10/7096	17/18670	0.06636	0.2095	0.1562	STAT6/STAT3/LY9/BATF/IL6/IL12RB1/IL12B/TBX21/MTOR/IL23A	10
BP	GO:0043968	histone H2A acetylation	10/7096	17/18670	0.06636	0.2095	0.1562	MORF4L2/RUVBL2/RUVBL1/MSL3/YEATS4/NAA40/BRD8/ING3/EPC1/ACTL6A	10
BP	GO:0050665	hydrogen peroxide biosynthetic process	10/7096	17/18670	0.06636	0.2095	0.1562	FYN/SOD1/STAT3/MPV17L/CYP1A2/CYBA/CYBB/MAOB/DUOXA1/CTNS	10
BP	GO:0051709	regulation of killing of cells of other organism	10/7096	17/18670	0.06636	0.2095	0.1562	CLEC7A/GAPDH/P2RX7/BCL2L11/FCER2/PGLYRP4/PRF1/BAD/IFNG/CXCL6	10
BP	GO:0060046	regulation of acrosome reaction	10/7096	17/18670	0.06636	0.2095	0.1562	STXBP1/PLB1/SPINK1/CCDC87/FAM170B/HYAL3/PLCB1/B4GALT1/CACNA1H/POMZP3	10
BP	GO:0070525	tRNA threonylcarbamoyladenosine metabolic process	10/7096	17/18670	0.06636	0.2095	0.1562	TPRKB/OSGEPL1/TRMT5/TRMT61B/PUS1/TP53RK/OSGEP/HSD17B10/MTO1/TRMT10C	10
BP	GO:1902931	negative regulation of alcohol biosynthetic process	10/7096	17/18670	0.06636	0.2095	0.1562	SOD1/NFKB1/APOE/ERLIN1/BMP2/ERLIN2/BMP5/SCAP/PLEK/CYP27B1	10
BP	GO:1903209	positive regulation of oxidative stress-induced cell death	10/7096	17/18670	0.06636	0.2095	0.1562	SOD1/FBXW7/MCL1/TLR4/SFPQ/MIR34A/MMP3/ENDOG/TLR6/FOXO3	10
BP	GO:1904380	endoplasmic reticulum mannose trimming	10/7096	17/18670	0.06636	0.2095	0.1562	RNF103/RNF139/TRIM13/EDEM1/EDEM2/MAN1B1/DERL2/RNF185/RNF5/OS9	10
BP	GO:0060401	cytosolic calcium ion transport	75/7096	171/18670	0.06707	0.2117	0.1578	SLC8A1/HTR2B/FYN/PTPN6/ATP2B4/LYN/MCOLN1/TPCN1/DIAPH1/TMBIM6/CXCL9/CXCL11/PTPRC/P2RX7/CXCL10/PKD2/TGFB1/ITPR1/PTK2B/MYO5A/CORO1A/P2RY6/MCU/RYR1/ABL1/GSTO1/PLCG2/PML/DMD/AFG3L2/TRPM2/LCK/CCR5/PSEN2/SRI/RASA3/BCL2/BAX/MS4A1/PRKACA/CYBA/MICU1/MCOLN2/F2R/GRIN2C/CAMK2D/PLCB1/CEMIP/ATP2A2/LETM1/CASQ1/CAPN3/CASQ2/HRC/BDKRB1/CD4/TMEM38B/LACRT/CACNB3/LIME1/SNCA/CX3CL1/P2RX2/CCL19/BAK1/CHERP/ATP1A2/CCR7/SLC8A3/MCOLN3/FAM155A/ADCYAP1R1/NTSR1/MICU2/P2RX5	75
BP	GO:0007548	sex differentiation	115/7096	270/18670	0.06747	0.2128	0.1587	WNT5A/SOD1/RETN/SRD5A1/NCOA4/SMAD5/FLNA/PLEKHA1/KITLG/LFNG/RDH10/LGR4/CEBPB/LRRC6/NUPR1/AKR1C3/AXL/UBE3A/REC8/HMGCS1/UTF1/ARRB1/NUDT1/CTNNA1/SGPL1/ZNF830/LEP/ROR2/ADAM15/INSR/PTX3/EIF2B5/HSPA5/VEGFA/DNAJC19/CASP3/TNFSF10/WDR19/HSD17B4/TIFAB/IDH1/SIRT1/BASP1/EIF2S2/MKKS/CCND1/ACVR1B/CITED2/ASPM/ATM/PATZ1/IMMP2L/BCL2L11/BMP5/MGST1/BMPR1A/BCL2/TBC1D20/BAX/HMGB2/TIPARP/ERCC1/CASP2/NUP107/INHBA/CTSV/HYAL3/YBX3/MMP14/FZD4/SLIT2/CCDC182/FANCG/MERTK/HSD17B3/CNTFR/TAF4/RHOBTB3/HOXA10/LHFPL2/NASP/FSHR/TLR3/INHA/REN/RXFP2/GREB1L/WNT2B/FOXF2/KMT2B/ASB1/TYRO3/FANCA/ZFP42/CENPI/IRX5/BAK1/MEA1/WNT7A/BCL2L2/EIF2B2/TFAP2C/CSDE1/GJA1/NRIP1/BMPR1B/ADCYAP1R1/AMHR2/MMP19/WT1/RBP4/FOXO3/LHX9/SLIT3/STRA6	115
BP	GO:1903312	negative regulation of mRNA metabolic process	37/7096	79/18670	0.06752	0.2129	0.1587	MYD88/ZFP36/SLC11A1/BARD1/TOB1/ZC3H14/SECISBP2/RNPS1/THRAP3/PAIP1/RBM42/SRSF10/HNRNPK/HNRNPA2B1/DHX9/SFSWAP/CDK9/HNRNPC/MAPKAPK2/HNRNPA0/SRSF6/SRSF7/HNRNPD/YBX3/RNF20/C1QBP/FMR1/SRSF4/VIP/MTOR/CCNT1/SAP18/TIRAP/NBAS/SYNCRIP/BOLL/TARDBP	37
BP	GO:1904375	regulation of protein localization to cell periphery	52/7096	115/18670	0.06765	0.213	0.1588	EZR/STX7/PLS1/ARF6/CSK/GBP1/RAB11A/CIB1/SQSTM1/TNF/EPHB2/ACTB/TGFB1/GRIPAP1/RHOG/GOPC/CDK5/HRAS/SAPCD2/NUMB/CNST/RAP1A/LRP1/SPTBN1/RHOQ/GRASP/CNPY4/RANGRF/NKD2/ITGA3/MMP14/EGFR/GPSM2/IQSEC2/STAC2/PID1/EPB41/VTI1B/TREM2/IFNG/STX8/KIF5B/EPB41L2/AP2M1/PRKCZ/GPC4/MISP/DAG1/CLIP3/RER1/PICALM/APPL1	52
BP	GO:0050796	regulation of insulin secretion	77/7096	176/18670	0.0678	0.213	0.1588	PPARD/HADH/SIRT4/ENY2/PER2/JAK2/FAM3D/TNF/HMGCR/DPP4/LRP5/PPP3CB/ITPR1/AACS/ARRB1/HIF1A/PIM3/ENHO/LEP/MCU/TCIRG1/IL1B/UQCC2/CCL5/C2CD2L/RAP1A/MPC2/LRP1/RFX3/TRPM4/DOC2B/RAC1/GLUD1/IRS2/SLC25A5/KLF7/SERP1/SRI/OXCT1/RPH3AL/GPR27/SLC16A1/SYTL4/CPT1A/PDX1/TM7SF3/PFKFB2/HMGN3/ICA1/CLOCK/GIPR/TCF7L2/BAD/SYT9/PLA2G6/IFNG/ARNTL/KIF5B/NDUFAF2/MAP4K4/SLC9B2/SOX4/SIDT2/ARL2BP/GCG/PFKL/NLGN2/GJA1/NR1H4/TARDBP/STXBP4/PRKCA/UCN3/RBP4/PSMD9/GHRL/PHPT1	77
BP	GO:0007431	salivary gland development	19/7096	37/18670	0.06783	0.213	0.1588	TNF/TGFB1/HGF/BMP7/EDA/PLXNA1/NRP1/PLXND1/EDAR/TGM2/PDGFA/EGFR/TGFB3/TFCP2L1/BTBD7/POLB/DAG1/TWSG1/LAMA1	19
BP	GO:0014037	Schwann cell differentiation	19/7096	37/18670	0.06783	0.213	0.1588	MPP5/SKI/SOD1/LAMB2/RELA/NRG1/CDK5/NAB1/NDRG1/EGR2/DICER1/ADAM22/SH3TC2/LGI4/LAMA2/DAG1/ERBB3/NTRK2/POU3F1	19
BP	GO:0038083	peptidyl-tyrosine autophosphorylation	19/7096	37/18670	0.06783	0.213	0.1588	FYN/LYN/HCK/PTK2B/INSR/FGR/IGF1R/VEGFA/ABL1/PTK6/ITK/LCK/PTK2/TEC/FRK/EGFR/ABL2/TXK/GREM1	19
BP	GO:0048846	axon extension involved in axon guidance	19/7096	37/18670	0.06783	0.213	0.1588	WNT5A/SEMA4B/ALCAM/CXCL12/MEGF8/SEMA4A/VEGFA/SEMA4C/SEMA4D/SEMA6B/NRP1/SEMA3B/NRP2/SEMA5A/SLIT2/SEMA5B/PLXNA3/BMPR2/SLIT3	19
BP	GO:1902284	neuron projection extension involved in neuron projection guidance	19/7096	37/18670	0.06783	0.213	0.1588	WNT5A/SEMA4B/ALCAM/CXCL12/MEGF8/SEMA4A/VEGFA/SEMA4C/SEMA4D/SEMA6B/NRP1/SEMA3B/NRP2/SEMA5A/SLIT2/SEMA5B/PLXNA3/BMPR2/SLIT3	19
BP	GO:1904358	positive regulation of telomere maintenance via telomere lengthening	19/7096	37/18670	0.06783	0.213	0.1588	MAP3K4/PKIB/NAF1/HNRNPA1/HNRNPA2B1/XRCC5/ATM/MAPKAPK5/CCT4/FBXO4/CCT8/ATR/MAPK1/RTEL1/ACD/PRKCQ/POT1/PNKP/NEK7	19
BP	GO:0070372	regulation of ERK1 and ERK2 cascade	127/7096	300/18670	0.06797	0.2134	0.1591	KLF4/FPR2/HTR2B/NOD2/FN1/GLIPR2/EZR/PTPN6/DUSP1/DUSP6/LYN/NOTCH2/CSK/GBP1/GPNMB/ATP6AP1/RAP1B/FLT1/PTPN2/MARCO/DUSP10/MIF/MAP2K1/CIB1/FBXW7/ACKR3/CD44/NLRP12/GSTP1/PTPRC/RRAS/TNF/CD74/EPHB2/APOE/HMGCR/SLAMF1/DUSP3/NDRG2/TGFB1/ARRB1/APIP/RAPGEF2/CD36/PTK2B/RANBP9/P2RY6/TLR4/PTPN22/FLT3/PDGFC/BMP2/HRAS/ABL1/IL1B/AGER/CCL5/MAP3K12/RASGRP1/RAP1A/SHC1/LRP1/HMGB1/TNFRSF11A/CCL7/NPTN/MFHAS1/CHI3L1/PDGFB/FLCN/DUSP4/CCL13/NRP1/PRKD2/GNAI2/CCL8/BMP4/TNIP1/RGS14/CHRNA10/FFAR4/LGALS9/PDGFA/BTN2A2/PRMT5/SPRY1/F2R/ABCA7/SPRED1/EGFR/CCL20/CCL26/SPRY2/HCRTR1/TREM2/HAVCR2/EPHB1/PIN1/GCNT2/PKHD1/CD4/FSHR/PRKCZ/CSF1R/TRPV4/C5AR2/PDE8A/APP/GPR183/CX3CL1/ITGB1BP1/CCL19/TIRAP/SLC30A10/GCG/CCL4/CCR7/FGF23/IL26/CCL24/HMGB4/PRKCA/SERPINF2/P2RY1/PDGFD/THPO/WNK2	127
BP	GO:0010818	T cell chemotaxis	15/7096	28/18670	0.06812	0.2136	0.1593	CCR2/OXSR1/WNT5A/CXCL11/CXCL10/CXCL13/CCL5/SLC12A2/TMEM102/PIK3CD/ADAM17/CCL26/PIK3CG/GPR183/CXCR3	15
BP	GO:0070861	regulation of protein exit from endoplasmic reticulum	15/7096	28/18670	0.06812	0.2136	0.1593	BCAP31/EDEM1/SAR1B/UBE2J1/UBE2G2/EDEM2/SAR1A/DERL2/INSIG1/YOD1/TMEM30A/TM9SF4/ERLEC1/OS9/SEC16B	15
BP	GO:0055067	monovalent inorganic cation homeostasis	68/7096	154/18670	0.06836	0.2141	0.1596	SLC8A1/ATP6V0D2/PDK4/GRN/SLC11A1/SLC9A9/ATP1A1/ATP6AP1/DMXL1/CHP1/ATP6V1C1/ATP6V0C/SLC9A1/AQP11/PDK2/TCIRG1/CLCN3/ATP6V1A/ATP4A/CLN3/VPS33A/SLC12A9/RAB20/ATP6V1G3/ATP1B2/ATP6V1B2/SLC9A8/LRRK2/RAB38/SLC9A7/ATP6V1D/ATP1B3/ROGDI/SLC12A2/ATP6AP1L/SLC12A8/MAFG/BCL2/GNAI2/ATP6V0E2/ATP1B1/CLN6/CLN5/SLC4A5/ATP6V1G2/SLC26A4/MAPK1/SNX5/SLC4A7/SLC4A1/SLC12A1/SLC12A7/KCNMA1/ATP6V1B1/CCKBR/SLC12A4/TM9SF4/ATP1A2/SPX/SLC4A11/SLC9C2/ATP12A/SLAMF8/SLC4A3/AVPR2/SLC12A6/C7/DMXL2	68
BP	GO:0061025	membrane fusion	68/7096	154/18670	0.06836	0.2141	0.1596	ANXA1/STX7/ATG7/STX11/GNAI3/CHP1/TAP2/TAP1/SEC22B/FOLR2/SAMD9L/C2CD5/VPS41/MX2/STXBP1/CORO1A/GCA/HYAL2/IZUMO1/UBXN2B/VAMP3/SAMD9/NSFL1C/RAB20/ANKRD27/BET1/RAB8A/DOC2B/GOSR2/GOSR1/CCR5/TAPBP/STX5/SPHK1/VPS18/NAPA/MX1/STX16/NKD2/VTI1A/RAB7B/NAPG/YKT6/DNM1L/STX18/CALR/HACE1/RAB8B/RABEP1/ANXA2P2/DCSTAMP/RAB3A/STX12/LYZL6/VTI1B/SYT9/STX8/SYT1/KIF5B/CD4/VPS16/VAMP1/SNAP29/SYT4/ANXA2/SNCA/VPS8/SPESP1	68
BP	GO:0006814	sodium ion transport	94/7096	218/18670	0.06838	0.2141	0.1596	SLC8A1/PKD2L1/SLC22A4/ATP2B4/SLC38A6/SLC5A3/SLC9A9/ATP1A1/SLC23A2/TPCN1/KLHL24/CHP1/NETO2/ACTN4/SIK1/YWHAH/SLC38A7/SLC22A5/P2RX7/SLC9A1/FXYD5/TESC/PKD2/FXYD6/COMMD3/TGFB1/MAGED2/SCN1B/ATP4A/CNNM4/DMD/TRPM4/TRPM2/ATP1B2/SLC28A3/SLC9A8/SLC38A1/SLC9A7/ATP1B3/ARF1/SLC12A2/HCN4/FXYD1/DNM2/NEDD4/ATP1B1/ADRB2/RANGRF/SLC10A1/SLC5A6/ABCB11/SLC4A5/SLC5A4/SLC13A2/SCN2B/SLC20A1/SLC41A1/COMMD1/CAMK2D/AHCYL1/CAV3/SLC5A8/SLC20A2/SLC8A2/SLC17A4/NKAIN4/COMMD9/FXYD7/SLC4A7/SLC24A4/PKP2/FXYD2/SCN8A/KIF5B/SLC12A1/SNTA1/SLC5A10/SCN9A/SCN3A/SLC9B2/ATP6V1B1/SLC24A2/HCN1/FXYD3/SLC5A9/FGF13/ATP1A2/SLC8A3/SLC4A11/SLC9C2/ATP12A/SLC5A2/CNTN1/WNK2	94
BP	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	54/7096	120/18670	0.06927	0.2168	0.1616	SKIL/SKI/FAM89B/SMAD7/RNF111/SMAD2/NREP/PBLD/LDLRAD4/ZBTB7A/TGFB1/ZNF451/HSPA5/CDKN2B/PMEPA1/CDKN1C/SDCBP/CHST11/SIRT1/CITED2/FLCN/BCL9L/PEG10/SNX6/STRAP/DNM2/ZNF703/MTMR4/LRG1/EID2/HTRA1/UBC/RASL11B/ITGA3/STUB1/ADAM17/CAV3/WFIKKN1/TRIM33/WNT1/LTBP4/ITGA8/TGFB3/TGFB1I1/PIN1/SPINT3/LEMD3/HSP90AB1/MEN1/GLG1/ENG/HTRA4/VEPH1/CD109	54
BP	GO:0007088	regulation of mitotic nuclear division	72/7096	164/18670	0.07013	0.2178	0.1624	IGF1/DUSP1/MAD2L2/NUP62/DYNC1LI1/RGCC/SPDL1/LRP5/CHMP4B/TGFB1/SMC5/INSR/CENPE/NAA10/UBXN2B/KLHL22/CDK5RAP2/IL1B/NSMCE2/TOM1L1/NSFL1C/CDKN1C/PHIP/TOM1L2/BMP7/PDGFB/CDC23/RCC1/ESPL1/ZNF207/LCMT1/ATM/ANAPC5/BUB3/SPHK1/NDC80/BMP4/CHMP2A/CDKN1B/KIF20B/MAD2L1BP/IL1A/GEN1/NUSAP1/ZW10/CHMP1A/VPS4B/UBE2C/PRMT5/NFE2L1/CDC26/RIOK2/DLGAP5/SMC3/ANAPC4/MTBP/MKI67/CDC27/CDC20/PIN1/PCID2/RB1/STAG1/CUL9/AURKAIP1/AURKA/ANAPC11/IK/CHMP1B/CCDC8/CEP85/L3MBTL1	72
BP	GO:0035821	modification of morphology or physiology of other organism	72/7096	164/18670	0.07013	0.2178	0.1624	S100A9/S100A12/RAB9A/SERPINB9/CLEC7A/ATG7/AZU1/GAPDH/MPEG1/P2RX7/CHD1/APOE/TGFB1/INSR/PTX3/HYAL2/NAPEPLD/KPNA4/TFAP4/IFI27/CD209/IGF2R/CASP8/TAF11/CCL5/VAPB/CTDP1/APOL1/PSMC3/RPS19/CCL13/BCL2L11/RXRA/FCER2/CCL8/TBC1D20/TNIP1/INPP5K/CCNK/CFL1/TYMS/PGLYRP4/RRAGA/EIF2AK2/PRF1/ANXA2P2/FMR1/HAMP/FBXL2/KPNA1/REG3G/BAD/SMC3/IFNG/HRG/GNLY/CD4/CTSG/EIF2AK4/PC/CSF1R/ANXA2/HPN/CCNT1/DAG1/KPNB1/CCL4/PPIB/NUCKS1/TARDBP/APCS/CXCL6	72
BP	GO:0001921	positive regulation of receptor recycling	9/7096	15/18670	0.07019	0.2178	0.1624	ARAP1/ECE1/VAMP3/RAB29/INPP5F/ANXA2P2/PSEN1/ANXA2/SNCA	9
BP	GO:0017014	protein nitrosylation	9/7096	15/18670	0.07019	0.2178	0.1624	S100A9/S100A8/ATP2B4/GAPDH/ADH5/NCOA7/DMD/SNTA1/OXR1	9
BP	GO:0018119	peptidyl-cysteine S-nitrosylation	9/7096	15/18670	0.07019	0.2178	0.1624	S100A9/S100A8/ATP2B4/GAPDH/ADH5/NCOA7/DMD/SNTA1/OXR1	9
BP	GO:0032486	Rap protein signal transduction	9/7096	15/18670	0.07019	0.2178	0.1624	RAP1B/TIMP2/RDX/RAPGEF2/RAP2C/PLK2/RAP2B/RAP1A/KIF14	9
BP	GO:0032736	positive regulation of interleukin-13 production	9/7096	15/18670	0.07019	0.2178	0.1624	IL17RA/NLRP3/IL1RAP/HLA-E/LGALS9/TNFSF4/TSLP/PRKCZ/IL17RB	9
BP	GO:0034134	toll-like receptor 2 signaling pathway	9/7096	15/18670	0.07019	0.2178	0.1624	TLR1/TLR2/LYN/TNIP2/TNFAIP3/MFHAS1/CYBA/TIRAP/TLR6	9
BP	GO:0035067	negative regulation of histone acetylation	9/7096	15/18670	0.07019	0.2178	0.1624	SPI1/SIN3A/ZNF451/SIRT1/NOC2L/BRCA1/SET/SNCA/TAF7	9
BP	GO:0042159	lipoprotein catabolic process	9/7096	15/18670	0.07019	0.2178	0.1624	CTSD/ABHD13/LYPLAL1/ABHD12/ABHD17C/APOE/LYPLA2/LDLR/ATM	9
BP	GO:0042559	pteridine-containing compound biosynthetic process	9/7096	15/18670	0.07019	0.2178	0.1624	GCH1/PCBD1/QDPR/PTS/SPR/ATIC/DHFR/FPGS/PCBD2	9
BP	GO:0048368	lateral mesoderm development	9/7096	15/18670	0.07019	0.2178	0.1624	SMAD2/MESP1/CITED2/BMPR1A/TEAD2/FOXF1/CER1/SMO/FOXH1	9
BP	GO:0060253	negative regulation of glial cell proliferation	9/7096	15/18670	0.07019	0.2178	0.1624	SKI/RNF10/CERS2/ASCL2/IDH2/DICER1/HES1/TERT/MIR146A	9
BP	GO:1900037	regulation of cellular response to hypoxia	9/7096	15/18670	0.07019	0.2178	0.1624	PINK1/TMBIM6/ENO1/KCNK2/CHCHD2/HYOU1/CD34/USP19/ROCK2	9
BP	GO:1903358	regulation of Golgi organization	9/7096	15/18670	0.07019	0.2178	0.1624	MAP2K1/PDE4DIP/RAB33B/STX5/DNM2/MAP2K2/STX18/MAPK1/EHD3	9
BP	GO:1903729	regulation of plasma membrane organization	9/7096	15/18670	0.07019	0.2178	0.1624	PLEKHM2/PRKCD/MYH9/DNM2/SYTL4/RAB3A/SH3GLB1/TMEFF2/ASAP1	9
BP	GO:2001185	regulation of CD8-positive, alpha-beta T cell activation	9/7096	15/18670	0.07019	0.2178	0.1624	IRF1/SH3RF1/CBFB/HFE/LILRB1/ZBTB7B/HLA-E/CD274/SOCS1	9
BP	GO:0060999	positive regulation of dendritic spine development	22/7096	44/18670	0.0702	0.2178	0.1624	APOE/ACTR2/LRP8/BAIAP2/ITSN1/PAFAH1B1/CAPRIN1/KALRN/ARF1/SHANK1/CPEB3/LPAR1/BHLHB9/DNM1L/PSEN1/FMR1/RELN/MTOR/C21orf91/SHANK3/ZMYND8/CAMK2B	22
BP	GO:0016072	rRNA metabolic process	108/7096	253/18670	0.07029	0.218	0.1625	DDX21/LYAR/DIS3L/RPP38/TSR1/GTPBP4/WDR46/UTP14A/ISG20/ISG20L2/XRN2/NAF1/DDX49/TFB1M/KRI1/SIRT7/TRMT112/KRR1/DEDD2/TRMT61B/RPP25/RPUSD2/SIRT1/ABT1/RPS24/TAF1B/SLFN13/WDR74/NOLC1/MRTO4/NAT10/DDX24/RPS21/THUMPD1/RPS9/FBL/RRP7A/RPS19/SUV39H1/NHP2/LAS1L/UTP15/XRN1/EXOSC2/GAR1/FTSJ3/RPF2/FDXACB1/RNASEL/DIMT1/ZCCHC4/WDR36/EXOSC7/RCL1/WDR75/PWP1/METTL15/DCAF13/NOL8/GTF3A/RRP15/IPPK/RIOK2/NOL10/SART1/RIOK3/ERI3/RPP40/GTF3C3/MPHOSPH6/TEX10/MRM1/IMP4/RPS16/WBP11/EXOSC9/NOC4L/DDX18/EXOSC3/DDX27/RPL7L1/FAM207A/FBLL1/NSUN5P1/POP7/REXO4/TSR2/DROSHA/MDN1/DDX54/MTOR/CD3EAP/DDX10/EXOSC6/EXOSC8/MRPS9/ZNHIT6/NUDT16/NOP10/C1D/UTP3/RRS1/ESF1/PA2G4/EXOSC5/DDX52/MRPL1/RPL10A	108
BP	GO:0034332	adherens junction organization	63/7096	142/18670	0.07033	0.218	0.1625	S100A10/ARF6/TSC1/CSK/PLEKHA7/SMAD7/TRIP6/LDB1/VCL/SLC9A1/DUSP3/PEAK1/RDX/CTNNA1/PTK2B/ACTN1/KIFC3/VEGFA/ABL1/IQSEC1/NUMB/TESK2/LRP1/PPM1F/SLK/RAC1/MAPRE2/CDH5/PTK2/ARHGAP6/BCR/LIMCH1/NRP1/BCL2/ZNF703/WDPCP/BCAS3/PVR/ITGA2/HIPK1/MMP14/DMTN/CORO1C/CLASP2/RAB8B/RCC2/CDH17/CDH10/NUMBL/PKP2/HRG/MAP4K4/CADM3/RHOA/CDH3/LIMS1/CDHR3/ITGB1BP1/ROCK2/CDH26/MACF1/PTPRJ/FMN1	63
BP	GO:0051453	regulation of intracellular pH	39/7096	84/18670	0.07045	0.2183	0.1627	ATP6V0D2/GRN/SLC11A1/SLC9A9/DMXL1/CHP1/ATP6V1C1/ATP6V0C/SLC9A1/AQP11/TCIRG1/CLCN3/ATP6V1A/CLN3/VPS33A/RAB20/ATP6V1G3/ATP6V1B2/SLC9A8/LRRK2/RAB38/SLC9A7/ATP6V1D/ROGDI/BCL2/ATP6V0E2/CLN6/CLN5/SLC4A5/ATP6V1G2/SLC4A7/SLC4A1/ATP6V1B1/TM9SF4/SLC4A11/SLC9C2/SLAMF8/SLC4A3/DMXL2	39
BP	GO:0048608	reproductive structure development	179/7096	431/18670	0.07071	0.2188	0.1631	CRIP1/JUNB/EPAS1/VDR/ANXA1/SOCS3/RBPJ/WNT5A/SOD1/RETN/SRD5A1/PTGS2/NCOA4/SPP1/PPARD/FLNA/PLEKHA1/ALKBH1/KITLG/MAP2K1/BIRC2/LFNG/RDH10/LGR4/ADAM19/CEBPB/LRRC6/PSAP/NUPR1/AKR1C3/PKD2/MAP3K4/DAZAP1/AXL/UBE3A/REC8/BPTF/HMGCS1/UTF1/ARRB1/HIF1A/NUDT1/CTNNA1/VASH1/SGPL1/ZNF830/LEP/FEM1B/ROR2/ADAM15/INSR/TFEB/PTX3/EIF2B5/EPOR/CEBPA/ASCL2/HSPA5/VEGFA/DNAJC19/CASP3/TNFSF10/CASP8/STOX2/WDR19/CDKN1C/CTSB/HSD17B4/HEY1/TIFAB/IDH1/SIRT1/BASP1/EIF2S2/BMP7/MKKS/CCND1/PDGFB/PCDH12/CITED2/DNAJB6/ASPM/PTK2/PLAG1/ATM/PATZ1/IMMP2L/ALOX15B/BCL2L11/BMP5/MGST1/RXRA/ASH1L/BCL2/BMP4/TBC1D20/BAX/HMGB2/TIPARP/ERCC1/CASP2/CDKN1B/DLX3/NUP107/SPINT1/INHBA/HTRA1/GRB2/CTSV/KDM5B/HYAL3/YBX3/KRT8/FZD5/MMP14/HES1/ADA/ARNT/PLCD1/EGFR/FZD4/HEY2/SLIT2/CCDC182/FANCG/MERTK/MAPK1/HSD17B3/CYP27B1/ZNF568/WDR77/TAF4/SNAI1/FOSL1/RHOBTB3/HOXA10/NASP/HSP90AB1/FSHR/TLR3/INHA/REN/RXFP2/MEN1/GREB1L/WNT2B/FOXF2/KMT2B/ASB1/TYRO3/FANCA/ZFP42/IRX5/BAK1/SMARCC1/MEA1/WNT7A/BCL2L2/EIF2B2/TFAP2C/CSDE1/GJA1/NRIP1/BMPR1B/AMHR2/MMP19/WT1/RBP4/PTCH1/GRHL2/E2F8/FOXO3/GHRL/CCNF/LHX9/NRK/BMPR2/SLIT3/STRA6	179
BP	GO:0098876	vesicle-mediated transport to the plasma membrane	44/7096	96/18670	0.07074	0.2188	0.1631	CSK/GGA2/RAB11A/ANKRD50/TRIM23/VAMP5/SYS1/EXOC6B/RAB31/EXOC1/GRIPAP1/ARF4/MICALL1/ARF5/GOPC/VAMP3/C16orf70/GRIP1/CNST/ANKRD27/BBS2/RAB8A/PREPL/SPTBN1/SNX27/ARF1/GOLPH3L/DNM2/CCDC93/GRASP/KIF13A/ARFRP1/COMMD1/RABEP1/LRRC7/VPS29/EXOC4/LLGL1/OPTN/ARF3/RAB26/MACF1/EXOC2/SNX17	44
BP	GO:0006805	xenobiotic metabolic process	56/7096	125/18670	0.07076	0.2188	0.1631	NQO1/EPHX1/S100A12/POR/CMBL/ACAA1/MGST2/GSTP1/AHRR/AKR7A2/CYP1B1/AKR7A3/CYB5B/CYP2J2/AKR1C1/CYP2S1/STAT5A/GSTO1/AHR/CES2/GSTA1/GSTM3/PTGES3/ARNT2/BPHL/MGST1/CYP2D6/CYP1A2/CBR3/CYP26B1/GSTM5/AS3MT/GSTM4/CYB5R3/ARNT/CES3/MGST3/RORA/NAT2/HSP90AB1/SULT1B1/CYP26A1/MARC2/FMO2/NAT1/CRYZ/CYP2W1/GHR/CYP2A6/CYP46A1/PHGDH/ALDH3A1/CYP2C8/PTGS1/CYP2U1/AIP	56
BP	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	56/7096	125/18670	0.07076	0.2188	0.1631	KLF4/CDKN2D/CDKN1A/GPNMB/ZNF655/RGCC/SLFN11/EZH2/PKD2/GIGYF2/BTG2/CDK4/CDKN2B/PLK2/SFN/PML/CDK2AP2/CCND1/ATM/TNKS1BP1/MUC1/CTDSPL/PLK3/NACC2/BCL2/PCNA/BAX/CRADD/CASP2/CTDSP1/RFWD3/CDKN1B/CDKN2C/CNOT4/FHL1/PLAGL1/ARID3A/BTN2A2/E2F4/CNOT7/GML/CTDSP2/MDM2/WEE1/RBL2/DCUN1D3/RB1/CNOT10/CARM1/JADE1/TRIAP1/AURKA/CDC73/SOX4/PRMT1/E2F8	56
BP	GO:0046605	regulation of centrosome cycle	28/7096	58/18670	0.07101	0.2191	0.1634	NUP62/ATF5/KAT2B/CHMP4B/TRIM37/CEP131/UBXN2B/PLK2/NPM1/CDK5RAP2/NSFL1C/CEP76/SPICE1/CHMP2A/GEN1/CHMP1A/VPS4B/BRCA1/CHORDC1/KAT2A/PKHD1/CEP120/AURKA/CHMP1B/ROCK2/CEP85/ALMS1/CCNF	28
BP	GO:0098930	axonal transport	28/7096	58/18670	0.07101	0.2191	0.1634	SOD1/BLOC1S2/UCHL1/KIF3B/HIF1A/HSPB1/AP3M2/TRAK2/PAFAH1B1/DTNBP1/BLOC1S6/KIF4A/ARL8A/BLOC1S3/NDEL1/BLOC1S1/BLOC1S4/AP3B1/MAP1A/FMR1/KIF1B/AP3M1/KIF5B/TRAK1/KIF1C/MGARP/ARL8B/TRIM46	28
BP	GO:0031050	dsRNA processing	25/7096	51/18670	0.0711	0.2191	0.1634	MAP2K1/SMAD2/AGO2/TGFB1/TSN/METTL3/BCDIN3D/HNRNPA2B1/MRPL44/PUM2/SNIP1/DICER1/NCOR1/TARBP2/BMP4/AGO1/MAP2K2/ZMPSTE24/EGFR/ZC3H7B/ZC3H10/DROSHA/TERT/ADAR/SRRT	25
BP	GO:0048146	positive regulation of fibroblast proliferation	25/7096	51/18670	0.0711	0.2191	0.1634	IGF1/FN1/CDKN1A/WNT5A/MIF/RNASEH2B/MYC/CD74/S100A6/CDK4/TGFB1/PDGFC/DHX9/PML/PDGFB/SPHK1/PDGFA/LIG4/EGFR/ANXA2P2/WNT1/FOSL2/CCNA2/ANXA2/PDGFD	25
BP	GO:0048641	regulation of skeletal muscle tissue development	25/7096	51/18670	0.0711	0.2191	0.1634	DLL1/FLOT1/KLHL41/HMGCR/TGFB1/UQCC2/NR1D2/S100B/NLN/MYOG/BCL2/CYP26B1/HDAC4/YBX3/LMOD3/PRKAA1/SHOX2/MEGF10/EPHB1/ARNTL/USP19/WNT10B/TLL2/MEF2C/MYF6	25
BP	GO:0051452	intracellular pH reduction	25/7096	51/18670	0.0711	0.2191	0.1634	ATP6V0D2/GRN/SLC11A1/DMXL1/ATP6V1C1/ATP6V0C/AQP11/TCIRG1/CLCN3/ATP6V1A/CLN3/RAB20/ATP6V1G3/ATP6V1B2/RAB38/ATP6V1D/ROGDI/BCL2/ATP6V0E2/CLN6/CLN5/ATP6V1G2/ATP6V1B1/SLAMF8/DMXL2	25
BP	GO:0070918	production of small RNA involved in gene silencing by RNA	25/7096	51/18670	0.0711	0.2191	0.1634	MAP2K1/SMAD2/AGO2/TGFB1/TSN/METTL3/BCDIN3D/HNRNPA2B1/MRPL44/PUM2/SNIP1/DICER1/NCOR1/TARBP2/BMP4/AGO1/MAP2K2/ZMPSTE24/EGFR/ZC3H7B/ZC3H10/DROSHA/TERT/ADAR/SRRT	25
BP	GO:0048640	negative regulation of developmental growth	51/7096	113/18670	0.07206	0.222	0.1655	RTN4R/CDKN1A/WNT5A/SEMA4B/SPP1/DUSP10/PLAC8/ULK2/RGS2/LGMN/IFRD1/PAK1/BCL11A/SEMA4A/ADRB1/CDK5/SEMA4C/SEMA4D/BBS2/SAV1/CTDP1/DCC/G6PD/PTK2/SEMA6B/NRP1/SEMA3B/BMP4/CDKN1B/YY1/ADRB2/KCNK2/SEMA5A/FSTL4/WWC2/MYOZ1/PPARA/CAV3/SEMA5B/PLXNA3/MAPK11/MEIS1/RTN4/FGF13/SOCS2/GJA1/RBP4/TLL2/PTCH1/WWC1/TRIM46	51
BP	GO:0051851	modification by host of symbiont morphology or physiology	36/7096	77/18670	0.0724	0.2227	0.166	RAB9A/AZU1/GAPDH/CHD1/APOE/PTX3/NAPEPLD/TFAP4/IFI27/IGF2R/TAF11/CCL5/CTDP1/PSMC3/CCL8/TBC1D20/INPP5K/CCNK/CFL1/ANXA2P2/FMR1/FBXL2/SMC3/CTSG/EIF2AK4/PC/CSF1R/ANXA2/HPN/CCNT1/CCL4/PPIB/NUCKS1/TARDBP/APCS/CXCL6	36
BP	GO:0048489	synaptic vesicle transport	67/7096	152/18670	0.07241	0.2227	0.166	APBA1/PINK1/STX11/DNM3/RAP1B/SYT11/BLOC1S2/P2RX7/CTBP2/GSK3B/STXBP1/UNC13B/SYNJ1/FBXL20/AP3M2/CDK5/RAB3GAP1/TMEM230/DTNBP1/RAP1A/BLOC1S6/DOC2B/PREPL/LRRK2/ADCY1/ARF1/TOR1A/DNM1/P2RX1/ADORA2B/VPS18/NAPA/DNM2/BLOC1S3/RAB5A/CAMK2A/CHRM2/DNM1L/BLOC1S1/CHRNA4/BLOC1S4/AP3B1/ATP2A2/DVL1/PSEN1/FMR1/RAB3A/CHRNB2/P2RY4/PPFIA3/SYT9/AP3M1/SYT1/SYT2/VAMP1/DOC2A/SNAP29/SYT4/CADPS2/SYT5/SNCA/RIMS2/WNT7A/PICALM/RAB27A/P2RY1/TRIM46	67
BP	GO:0097480	establishment of synaptic vesicle localization	67/7096	152/18670	0.07241	0.2227	0.166	APBA1/PINK1/STX11/DNM3/RAP1B/SYT11/BLOC1S2/P2RX7/CTBP2/GSK3B/STXBP1/UNC13B/SYNJ1/FBXL20/AP3M2/CDK5/RAB3GAP1/TMEM230/DTNBP1/RAP1A/BLOC1S6/DOC2B/PREPL/LRRK2/ADCY1/ARF1/TOR1A/DNM1/P2RX1/ADORA2B/VPS18/NAPA/DNM2/BLOC1S3/RAB5A/CAMK2A/CHRM2/DNM1L/BLOC1S1/CHRNA4/BLOC1S4/AP3B1/ATP2A2/DVL1/PSEN1/FMR1/RAB3A/CHRNB2/P2RY4/PPFIA3/SYT9/AP3M1/SYT1/SYT2/VAMP1/DOC2A/SNAP29/SYT4/CADPS2/SYT5/SNCA/RIMS2/WNT7A/PICALM/RAB27A/P2RY1/TRIM46	67
BP	GO:0048017	inositol lipid-mediated signaling	80/7096	184/18670	0.07294	0.2227	0.166	KLF4/IGF1/HTR2B/FYN/EZR/PTPN6/LYN/FLT1/PPARD/PLEKHA1/PRR5/JAK2/TNF/GAB1/PTPN13/PLD1/HCLS1/UBE3A/EXOC1/IER3/HGF/PTAFR/LEP/INSR/PIK3IP1/NCF1/FLT3/PDGFC/EPOR/FGR/IGF1R/CAT/CCL5/PLCG2/RASGRP1/PIK3R6/SEMA4D/SIRT1/PPP1R16B/IRS2/PDGFB/PPP2R5C/PTK2/CEP55/NYAP1/NEDD4/PIK3CD/OSM/GPR143/INPP5F/UNC5B/PDGFA/BTN2A2/F2R/SERPINA12/PLCB1/C1QBP/EGFR/IL18/PLD2/MAPK1/STAMBP/FBXL2/OGT/MAZ/FSHR/PPP2R5B/PIK3CG/RELN/CSF1R/PIP5K1B/LIME1/RHOA/TYRO3/NLRC3/ERBB3/PDGFD/NTRK2/PIK3CB/PI4KB	80
BP	GO:0046427	positive regulation of JAK-STAT cascade	41/7096	89/18670	0.07314	0.2227	0.166	IGF1/FYN/SOCS3/LYN/PARP9/AKR1B1/STAT3/ADIPOR1/CD40/JAK2/IL15/TNF/HCLS1/CYP1B1/PTK2B/LEP/FLT3/PTK6/CCL5/TNFRSF18/IL6ST/IL6/HDAC2/CLCF1/OSM/CD300A/HES1/F2R/CNTF/IL18/SOCS1/IL3/TSLP/IFNG/TNFSF18/IL12B/CSF1R/ARL2BP/GHR/IL26/IL23A	41
BP	GO:0001893	maternal placenta development	18/7096	35/18670	0.07328	0.2227	0.166	JUNB/VDR/PTGS2/SPP1/PPARD/DAZAP1/EPOR/STOX2/CTSB/RXRA/ASH1L/CTSV/MAPK1/CYP27B1/MEN1/GJA1/GHRL/BMPR2	18
BP	GO:0030262	apoptotic nuclear changes	18/7096	35/18670	0.07328	0.2227	0.166	AIFM1/DNASE2B/CASP3/NMNAT1/DFFA/DEDD2/HMGB1/IL6/DICER1/BAX/HMGB2/ST20/KPNA1/KPNB1/ENDOG/DNASE2/TOP2A/MIR146A	18
BP	GO:0032801	receptor catabolic process	18/7096	35/18670	0.07328	0.2227	0.166	LGMN/APOE/TGFB1/CDK5/FURIN/KIF16B/DTX3L/AP2A2/NEDD4/AP2S1/MTMR2/AP2A1/GPRASP1/ANXA2P2/RNF43/SH3GLB1/AP2M1/ANXA2	18
BP	GO:0045070	positive regulation of viral genome replication	18/7096	35/18670	0.07328	0.2227	0.166	STAU1/DDB1/ADARB1/CCL5/SRPK2/VAPB/DDX3X/TARBP2/TBC1D20/TOP2B/IFIT1/SRPK1/CNOT7/PKN2/ADAR/PPIB/NUCKS1/TOP2A	18
BP	GO:0046131	pyrimidine ribonucleoside metabolic process	18/7096	35/18670	0.07328	0.2227	0.166	UPP1/AK3/CDADC1/CTPS2/CMPK1/APOBEC3G/APOBEC3C/NME3/APOBEC2/NME4/NME1/UCK1/APOBEC3B/CTPS1/CAD/CDA/UCKL1/UPP2	18
BP	GO:0046466	membrane lipid catabolic process	18/7096	35/18670	0.07328	0.2227	0.166	FUCA1/ASAH1/HEXB/GM2A/MGST2/PSAP/CYP1B1/SGPL1/GALC/PRKCD/GLA/ENPP7/SPHK1/NAGA/ACER3/NEU1/SMPD1/SMPD2	18
BP	GO:0060251	regulation of glial cell proliferation	18/7096	35/18670	0.07328	0.2227	0.166	LYN/SKI/RNF10/CERS2/TNF/ASCL2/IL1B/CREB1/ETV5/IL6/IDH2/PLAG1/DICER1/HES1/PPP1CC/TERT/MTOR/MIR146A	18
BP	GO:0061458	reproductive system development	180/7096	434/18670	0.07329	0.2227	0.166	CRIP1/JUNB/EPAS1/VDR/ANXA1/SOCS3/RBPJ/WNT5A/SOD1/RETN/SRD5A1/PTGS2/NCOA4/SPP1/PPARD/FLNA/PLEKHA1/ALKBH1/KITLG/MAP2K1/BIRC2/LFNG/RDH10/LGR4/ADAM19/CEBPB/LRRC6/PSAP/NUPR1/AKR1C3/PKD2/MAP3K4/DAZAP1/AXL/UBE3A/REC8/BPTF/HMGCS1/UTF1/ARRB1/HIF1A/NUDT1/CTNNA1/VASH1/SGPL1/ZNF830/LEP/FEM1B/ROR2/ADAM15/INSR/TFEB/PTX3/EIF2B5/EPOR/CEBPA/ASCL2/HSPA5/VEGFA/DNAJC19/CASP3/TNFSF10/CASP8/STOX2/WDR19/CDKN1C/CTSB/HSD17B4/HEY1/TIFAB/IDH1/SIRT1/BASP1/EIF2S2/BMP7/MKKS/CCND1/PDGFB/PCDH12/CITED2/DNAJB6/ASPM/PTK2/PLAG1/ATM/PATZ1/IMMP2L/ALOX15B/BCL2L11/BMP5/MGST1/RXRA/ASH1L/BCL2/BMP4/TBC1D20/BAX/HMGB2/TIPARP/ERCC1/CASP2/CDKN1B/DLX3/NUP107/SPINT1/INHBA/HTRA1/GRB2/CTSV/KDM5B/HYAL3/YBX3/KRT8/FZD5/MMP14/HES1/ADA/ARNT/PLCD1/EGFR/FZD4/HEY2/PLEKHA5/SLIT2/CCDC182/FANCG/MERTK/MAPK1/HSD17B3/CYP27B1/ZNF568/WDR77/TAF4/SNAI1/FOSL1/RHOBTB3/HOXA10/NASP/HSP90AB1/FSHR/TLR3/INHA/REN/RXFP2/MEN1/GREB1L/WNT2B/FOXF2/KMT2B/ASB1/TYRO3/FANCA/ZFP42/IRX5/BAK1/SMARCC1/MEA1/WNT7A/BCL2L2/EIF2B2/TFAP2C/CSDE1/GJA1/NRIP1/BMPR1B/AMHR2/MMP19/WT1/RBP4/PTCH1/GRHL2/E2F8/FOXO3/GHRL/CCNF/LHX9/NRK/BMPR2/SLIT3/STRA6	180
BP	GO:0019827	stem cell population maintenance	69/7096	157/18670	0.07333	0.2227	0.166	KLF4/DLL1/SPI1/SKI/NOTCH2/RBPJ/STAT3/KLF10/ZNF358/SMAD2/MED10/LDB1/PAF1/METTL14/ZNF322/NCOA3/PCM1/METTL3/LOXL2/ASCL2/PAX8/MED15/POLR2L/MED27/MED28/RAF1/SAV1/BMP7/BCL9L/TAL1/POLR2H/ASPM/BMPR1A/HOOK3/KDM2B/SETD6/LIG4/POLR2F/MED30/HES1/POLR2D/LEO1/VPS72/POLR2K/SS18/SMC3/ZFP36L2/HNF1B/DIS3L2/EIF4E/FANCD2/FZD7/ELF5/ESRRB/NR2E1/FOXP1/CDC73/ZNF706/SOX4/SRRT/WNT7A/POLR2I/GNL3/ZSCAN10/SMO/LBH/EIF4ENIF1/TET1/FOXO3	69
BP	GO:0000725	recombinational repair	60/7096	135/18670	0.07342	0.2227	0.166	USP51/ZFYVE26/MAD2L2/RAD51AP1/MCM6/MCM2/HUS1B/NABP1/UBE2N/KLHL15/ERCC4/MAGEF1/ACTR2/PPP4C/PPP4R2/REC8/SMC5/RNF138/RPA1/RMI2/RAD51B/CCDC155/PALB2/NSMCE2/SAMHD1/SMCHD1/SFPQ/AP5S1/RHNO1/ATM/RAD52/XRCC1/FUS/RFWD3/YY1/RMI1/RAD54B/SWI5/GEN1/TIMELESS/RECQL/KDM4D/POLL/BRCA1/GINS4/MCM5/RTEL1/SWSAP1/TEX15/LIG3/MCM8/ZSWIM7/AUNIP/WAS/TONSL/NUCKS1/SPIDR/FEN1/RECQL4/FIGNL1	60
BP	GO:0030206	chondroitin sulfate biosynthetic process	14/7096	26/18670	0.07346	0.2227	0.166	VCAN/CHSY1/CHST13/CSGALNACT1/CSPG4/XYLT1/CHST11/SLC35D1/B3GALT6/XYLT2/CSGALNACT2/BCAN/CHST12/CHST7	14
BP	GO:0045992	negative regulation of embryonic development	14/7096	26/18670	0.07346	0.2227	0.166	WNT5A/LFNG/PRKACB/TULP3/FUZ/BMP7/MESP1/NRARP/BMP4/PRKACA/SNAI1/GPR161/FZD7/TRAF3IP1	14
BP	GO:0097066	response to thyroid hormone	14/7096	26/18670	0.07346	0.2227	0.166	GCLM/AKR1B1/CTSS/GAS2L1/RDX/LMO2/GCLC/CTSB/KLF9/PPARGC1A/CRLS1/TOMM20/ANXA2/HPN	14
BP	GO:1904353	regulation of telomere capping	14/7096	26/18670	0.07346	0.2227	0.166	ERCC4/MAP3K4/PKIB/ATM/MAPKAPK5/XRCC1/ERCC1/HNRNPD/USP7/MAPK1/RTEL1/PRKCQ/PNKP/NEK7	14
BP	GO:0000819	sister chromatid segregation	82/7096	189/18670	0.07351	0.2227	0.166	DUSP1/MAD2L2/NUP62/RAB11A/DYNC1LI1/FBXW7/SPDL1/RAN/CHMP4B/PSRC1/REC8/SMC5/SEH1L/PDS5A/LATS1/CENPE/NAA10/RMI2/KLHL22/CDK5RAP2/DSCC1/NSMCE2/KIF4A/SPAG5/SFPQ/MIS12/CDC23/ESPL1/ZNF207/CENPC/LCMT1/SMC2/ATM/ANAPC5/CHAMP1/NCAPD3/BUB3/PHF23/AKAP8/NDC80/CHMP2A/CTCF/TOP2B/DSN1/NUF2/GEN1/NUSAP1/INCENP/ZW10/CHMP1A/VPS4B/CENPK/MOS/TUBG2/CDC26/STAG3/RIOK2/DLGAP5/KIF2C/SMC3/KATNB1/ANAPC4/DIS3L2/CDC27/CDC20/PCID2/RB1/STAG1/ANAPC11/STAG3L3/IK/KPNB1/MCMBP/MSTO1/CHMP1B/RRS1/FEN1/KIF14/BOD1/HORMAD1/PRC1/TOP2A	82
BP	GO:0000054	ribosomal subunit export from nucleus	8/7096	13/18670	0.0738	0.2227	0.166	RAN/EIF6/NPM1/ZNF593/NUP88/LTV1/RIOK2/RRS1	8
BP	GO:0002281	macrophage activation involved in immune response	8/7096	13/18670	0.0738	0.2227	0.166	GRN/SBNO2/TICAM1/TYROBP/TREM2/HAVCR2/SUCNR1/LBP	8
BP	GO:0006012	galactose metabolic process	8/7096	13/18670	0.0738	0.2227	0.166	GALM/GALE/GALK1/PPARGC1A/PGM2/GALT/B4GALT1/SLC35A2	8
BP	GO:0009313	oligosaccharide catabolic process	8/7096	13/18670	0.0738	0.2227	0.166	HEXB/MANBA/GM2A/MAN2B1/CTBS/NEU1/MAN2B2/TREH	8
BP	GO:0010745	negative regulation of macrophage derived foam cell differentiation	8/7096	13/18670	0.0738	0.2227	0.166	NFKBIA/CETP/NR1H2/ABCA1/ABCA5/ABCG1/NR1H3/PPARA	8
BP	GO:0010870	positive regulation of receptor biosynthetic process	8/7096	13/18670	0.0738	0.2227	0.166	JAK2/HIF1A/HNRNPK/HDAC2/SCAP/NR1H3/IFNG/CNPY2	8
BP	GO:0016024	CDP-diacylglycerol biosynthetic process	8/7096	13/18670	0.0738	0.2227	0.166	CDS1/GPAM/CDS2/AGPAT3/AGPAT4/AGPAT5/AGPAT1/AGPAT2	8
BP	GO:0030007	cellular potassium ion homeostasis	8/7096	13/18670	0.0738	0.2227	0.166	ATP1A1/ATP4A/ATP1B2/ATP1B3/ATP1B1/KCNMA1/ATP1A2/ATP12A	8
BP	GO:0032096	negative regulation of response to food	8/7096	13/18670	0.0738	0.2227	0.166	NUCB2/LEP/BBS2/MKKS/BBS4/PPARA/SPX/NENF	8
BP	GO:0032099	negative regulation of appetite	8/7096	13/18670	0.0738	0.2227	0.166	NUCB2/LEP/BBS2/MKKS/BBS4/PPARA/SPX/NENF	8
BP	GO:0032488	Cdc42 protein signal transduction	8/7096	13/18670	0.0738	0.2227	0.166	APOE/ABL1/ABCA1/RHOU/NRP1/RHOV/APOA1/WAS	8
BP	GO:0033623	regulation of integrin activation	8/7096	13/18670	0.0738	0.2227	0.166	PTGER4/FBLIM1/CXCL13/P2RY12/PLEK/CDH17/SKAP1/KIF14	8
BP	GO:0033750	ribosome localization	8/7096	13/18670	0.0738	0.2227	0.166	RAN/EIF6/NPM1/ZNF593/NUP88/LTV1/RIOK2/RRS1	8
BP	GO:0036109	alpha-linolenic acid metabolic process	8/7096	13/18670	0.0738	0.2227	0.166	ACAA1/ELOVL5/SCP2/ACOX1/HSD17B4/ABCD1/FADS2/ACOT8	8
BP	GO:0043201	response to leucine	8/7096	13/18670	0.0738	0.2227	0.166	KLHL22/RRAGD/PPARGC1A/PDX1/SESN1/UBR1/MTOR/SESN2	8
BP	GO:0043248	proteasome assembly	8/7096	13/18670	0.0738	0.2227	0.166	OTUD6B/PSMD11/PSMG1/ADRM1/PSMD13/POMP/PSMD4/PSMD9	8
BP	GO:0045059	positive thymic T cell selection	8/7096	13/18670	0.0738	0.2227	0.166	PTPN2/PTPRC/CD74/SRF/CD3D/CD3G/FOXN1/CD3E	8
BP	GO:0045078	positive regulation of interferon-gamma biosynthetic process	8/7096	13/18670	0.0738	0.2227	0.166	CLEC7A/CEBPG/EBI3/CD276/TLR8/TLR3/TNFRSF13C/IL12B	8
BP	GO:0071415	cellular response to purine-containing compound	8/7096	13/18670	0.0738	0.2227	0.166	SLC8A1/P2RY6/RYR1/TRPM2/PPARGC1A/CASQ2/TMEM38B/P2RY1	8
BP	GO:0090713	immunological memory process	8/7096	13/18670	0.0738	0.2227	0.166	TSC1/TNFRSF14/BCL6/FGL2/IL12RB1/TNFSF4/IL12B/IL23A	8
BP	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading	8/7096	13/18670	0.0738	0.2227	0.166	GBP1/ACTN4/KANK1/DMTN/CORO1C/RCC2/TACSTD2/ITGB1BP1	8
BP	GO:1900225	regulation of NLRP3 inflammasome complex assembly	8/7096	13/18670	0.0738	0.2227	0.166	GBP5/CD36/TLR4/MEFV/CPTP/EIF2AK2/NLRC3/TLR6	8
BP	GO:1902285	semaphorin-plexin signaling pathway involved in neuron projection guidance	8/7096	13/18670	0.0738	0.2227	0.166	PLXNB2/PLXNC1/PLXNA1/NRP1/PLXND1/NRP2/PLXNA3/PLXNA2	8
BP	GO:1904293	negative regulation of ERAD pathway	8/7096	13/18670	0.0738	0.2227	0.166	SGTA/UBE2J1/UBE2G2/DERL2/YOD1/UBXN1/ERLEC1/OS9	8
BP	GO:0070988	demethylation	33/7096	70/18670	0.07414	0.2236	0.1667	POR/JMJD6/ALKBH1/KDM1B/TET2/KDM7A/HSF4/USP9X/KDM2A/ALKBH4/APOBEC3G/TDG/APOBEC3C/KDM4B/OTUD4/APOBEC2/CYP2D6/FTO/CYP1A2/MMACHC/KDM2B/KDM8/KDM5B/KDM6B/KDM4D/USP7/APOBEC3B/KDM5C/ALKBH2/UBE2B/CYP2C8/TET1/KDM4A	33
BP	GO:0007179	transforming growth factor beta receptor signaling pathway	86/7096	199/18670	0.07452	0.2246	0.1675	FOS/SKIL/APPL2/ACVR2B/SKI/ARHGEF18/FAM89B/ITGB5/SMAD5/SMAD7/RNF111/SMAD2/F11R/NREP/PBLD/LDLRAD4/ZBTB7A/TGFB1/ZNF451/HPGD/HSPA5/CDKN2B/USP9X/PMEPA1/LTBP3/FURIN/NLK/CDKN1C/SDCBP/CHST11/PML/CREB1/SIRT1/ACVR1B/CDH5/CITED2/FLCN/BCL9L/PEG10/PTK2/ZYX/SNX6/BMPR1A/TAB1/STRAP/DNM2/ZNF703/MTMR4/LRG1/EID2/HTRA1/UBC/RASL11B/ITGA3/STUB1/PXN/ADAM17/CAV3/WFIKKN1/ADAM9/TRIM33/WNT1/LTBP4/ITGA8/TGFB3/TGFB1I1/PIN1/GCNT2/SPINT3/LEMD3/HSP90AB1/MEN1/GLG1/PRKCZ/RHOA/ENG/HTRA4/APPL1/BMPR1B/AMHR2/TWSG1/VEPH1/CD109/FOXH1/BMPR2/GDF5	86
BP	GO:0002637	regulation of immunoglobulin production	30/7096	63/18670	0.07556	0.2275	0.1696	IL27RA/MAD2L2/STAT6/TMBIM6/BCL6/CD40/IL4R/PTPRC/TNF/CD22/TGFB1/TRAF6/HLA-E/GPI/IL6/MLH1/PARP3/CLCF1/TRAF2/TFRC/TNFSF4/IL13RA2/TNFRSF4/EXOSC3/TBX21/APLF/EXOSC6/PAXIP1/ATAD5/RBP4	30
BP	GO:0046686	response to cadmium ion	30/7096	63/18670	0.07556	0.2275	0.1696	FOS/SOD1/HMOX1/AKR1C3/ALAD/NUDT1/CYB5A/NCF1/CAT/GCLC/MTF1/SUMO1/HAAO/SPARC/CYP1A2/MAPK8/MMP9/PCNA/ERCC1/CDKN1B/GSS/CYBB/SORD/EGFR/MAPK1/ATP7A/TERT/CHUK/DAXX/MAPK9	30
BP	GO:2000401	regulation of lymphocyte migration	30/7096	63/18670	0.07556	0.2275	0.1696	CCR2/IL27RA/OXSR1/WNT5A/TNFRSF14/ADAM8/CXCL10/CXCL12/DOCK8/PTK2B/CXCL13/ITGA4/AIF1/CCL5/CRK/CCL7/CD200R1/CD99L2/TMEM102/CCR6/MADCAM1/GCSAM/FADD/ADAM17/CCL20/MSN/C10orf99/RHOA/APP/CCL4	30
BP	GO:0007612	learning	64/7096	145/18670	0.07569	0.2277	0.1698	NRGN/FOS/FYN/TLR2/PRKAR2B/ATP8A1/PTGS2/LGMN/SLC7A11/EPHB2/KRAS/HMGCR/BTG2/ACTR2/CIC/PPP3CB/CLN8/HIF1A/ARF4/SYNJ1/SRF/INSR/CDK5/CLN3/CREB1/NPTN/KALRN/ARC/ADCY3/RGS14/SYNGAP1/SHANK1/NPAS4/VDAC1/C1QL1/ATXN1L/SLC8A2/MAP1A/CHRNB2/IFT20/FOSL1/ATXN1/RIN1/DBH/EIF2AK4/OPRL1/RELN/VDAC3/MTOR/BRSK1/APP/SLC24A2/FGF13/ATP1A2/SLC8A3/CTNS/ATAD1/SHANK3/AAAS/TACR2/NTSR1/NTRK2/SYNPO/STRA6	64
BP	GO:0010559	regulation of glycoprotein biosynthetic process	21/7096	42/18670	0.07582	0.2277	0.1698	IGF1/CHP1/AGO2/IL15/SOAT1/ITM2B/ARFGEF1/ITM2A/BACE2/AATF/BCL2/ABCA7/POMT1/PLCB1/POMT2/TCF7L2/NECAB3/HBEGF/CCL19/CCR7/ACOT8	21
BP	GO:0017145	stem cell division	21/7096	42/18670	0.07582	0.2277	0.1698	NCOA3/PAFAH1B1/NUMB/ARHGEF2/CDK2AP2/ETV5/ASPM/AKNA/EVI2B/DCT/ZFP36L2/NUMBL/FZD7/SOX5/ESRRB/PRDM15/ZBTB16/FGF13/WNT7A/GNL3/LBH	21
BP	GO:0065002	intracellular protein transmembrane transport	27/7096	56/18670	0.07649	0.2277	0.1698	TIMM23B/PEX12/C2CD5/PEX16/SEC62/SEC61B/HSPA5/DNAJC19/TIMM17A/TIMM21/GRPEL1/RTN2/BCR/GRPEL2/TOMM40L/PEX13/TOMM40/TOMM20/TIMM22/PEX14/AGK/DNAJC15/TIMM50/SEC61A2/TRAM1/TIMM44/TIMM9	27
BP	GO:1903018	regulation of glycoprotein metabolic process	24/7096	49/18670	0.0767	0.2277	0.1698	IGF1/CHP1/AGO2/IL15/SOAT1/CST3/ITM2B/PTX3/ARFGEF1/ITM2A/BACE2/AATF/BCL2/ABCA7/POMT1/PLCB1/POMT2/TCF7L2/NECAB3/HBEGF/CCL19/CCR7/APCS/ACOT8	24
BP	GO:0000185	activation of MAPKKK activity	7/7096	11/18670	0.07685	0.2277	0.1698	TNF/GADD45B/MAP4K5/MAP4K2/MAP4K3/TAB1/MAP4K1	7
BP	GO:0001574	ganglioside biosynthetic process	7/7096	11/18670	0.07685	0.2277	0.1698	B4GALT6/B4GALNT1/B4GALT5/ST8SIA4/ST6GALNAC3/ST6GALNAC6/ST3GAL5	7
BP	GO:0001731	formation of translation preinitiation complex	7/7096	11/18670	0.07685	0.2277	0.1698	EIF2D/EIF4B/EIF2S2/EIF4H/MCTS1/EIF5/TICRR	7
BP	GO:0001767	establishment of lymphocyte polarity	7/7096	11/18670	0.07685	0.2277	0.1698	DOCK8/FLOT2/SNX27/MYH9/CYP26B1/CCL19/CCR7	7
BP	GO:0001778	plasma membrane repair	7/7096	11/18670	0.07685	0.2277	0.1698	MYOF/SYT11/MYH9/ANXA6/SYTL4/CAV3/RAB3A	7
BP	GO:0002836	positive regulation of response to tumor cell	7/7096	11/18670	0.07685	0.2277	0.1698	CD226/FBXO38/PVR/CD274/CRTAM/HRG/IL12B	7
BP	GO:0002839	positive regulation of immune response to tumor cell	7/7096	11/18670	0.07685	0.2277	0.1698	CD226/FBXO38/PVR/CD274/CRTAM/HRG/IL12B	7
BP	GO:0007256	activation of JNKK activity	7/7096	11/18670	0.07685	0.2277	0.1698	ERCC6/MAP3K12/MLKL/MAP3K11/MAP3K13/NRK/MAP3K9	7
BP	GO:0009151	purine deoxyribonucleotide metabolic process	7/7096	11/18670	0.07685	0.2277	0.1698	DGUOK/NUDT1/ADK/GUK1/SAMHD1/ADA/NUDT16	7
BP	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	7/7096	11/18670	0.07685	0.2277	0.1698	EXTL2/NDST2/HS2ST1/EXT2/EXT1/CSGALNACT1/NDST1	7
BP	GO:0019852	L-ascorbic acid metabolic process	7/7096	11/18670	0.07685	0.2277	0.1698	SLC23A2/SLC2A3/AKR1A1/CYB5A/GCLC/GSTO1/CYB5R3	7
BP	GO:0030422	production of siRNA involved in RNA interference	7/7096	11/18670	0.07685	0.2277	0.1698	AGO2/TSN/MRPL44/DICER1/TARBP2/DROSHA/TERT	7
BP	GO:0032060	bleb assembly	7/7096	11/18670	0.07685	0.2277	0.1698	EMP3/P2RX7/EMP2/LPAR3/EMP1/LPAR1/MYLK	7
BP	GO:0033089	positive regulation of T cell differentiation in thymus	7/7096	11/18670	0.07685	0.2277	0.1698	EGR3/ADAM8/IL7R/RASGRP1/TESPA1/VNN1/ADA	7
BP	GO:0033632	regulation of cell-cell adhesion mediated by integrin	7/7096	11/18670	0.07685	0.2277	0.1698	DPP4/SWAP70/CXCL13/CCL5/ADA/SKAP1/CD3E	7
BP	GO:0034115	negative regulation of heterotypic cell-cell adhesion	7/7096	11/18670	0.07685	0.2277	0.1698	KLF4/MYADM/MBP/MAPK7/IL1RN/APOA1/MAP2K5	7
BP	GO:0039532	negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway	7/7096	11/18670	0.07685	0.2277	0.1698	NPLOC4/SEC14L1/C1QBP/GPATCH3/RIOK3/NLRX1/TSPAN6	7
BP	GO:0040015	negative regulation of multicellular organism growth	7/7096	11/18670	0.07685	0.2277	0.1698	PLAC8/LGMN/ADRB1/BBS2/ADRB2/SOCS2/PTCH1	7
BP	GO:0046501	protoporphyrinogen IX metabolic process	7/7096	11/18670	0.07685	0.2277	0.1698	FECH/UROD/ALAD/CPOX/IREB2/EIF2AK1/ALAS1	7
BP	GO:0060992	response to fungicide	7/7096	11/18670	0.07685	0.2277	0.1698	KLF4/KLF2/SRD5A1/XRN1/KDM5B/KDM6B/IMPACT	7
BP	GO:0070587	regulation of cell-cell adhesion involved in gastrulation	7/7096	11/18670	0.07685	0.2277	0.1698	KLF4/MYADM/MBP/MAPK7/IL1RN/APOA1/MAP2K5	7
BP	GO:0071803	positive regulation of podosome assembly	7/7096	11/18670	0.07685	0.2277	0.1698	TNF/LCP1/FSCN1/MSN/RHOA/ASAP1/MAPK9	7
BP	GO:0072608	interleukin-10 secretion	7/7096	11/18670	0.07685	0.2277	0.1698	LILRA5/TNFRSF21/LILRB1/ISG15/CD274/LGALS9/PRKCZ	7
BP	GO:0072611	interleukin-13 secretion	7/7096	11/18670	0.07685	0.2277	0.1698	ARG2/IL17RA/LILRA5/TNFRSF21/LGALS9/PRKCZ/IL17RB	7
BP	GO:0090073	positive regulation of protein homodimerization activity	7/7096	11/18670	0.07685	0.2277	0.1698	ARF6/SYAP1/TRAF2/GNL3L/TIRAP/TRAF4/MEF2C	7
BP	GO:1902563	regulation of neutrophil activation	7/7096	11/18670	0.07685	0.2277	0.1698	ITGAM/GRN/PTAFR/ABR/BCR/CD300A/PRAM1	7
BP	GO:1905245	regulation of aspartic-type peptidase activity	7/7096	11/18670	0.07685	0.2277	0.1698	GRN/LYN/AGER/PICALM/ROCK2/BIN1/EFNA3	7
BP	GO:1905668	positive regulation of protein localization to endosome	7/7096	11/18670	0.07685	0.2277	0.1698	EZR/ABHD17C/RDX/DTX3L/MGAT3/MSN/ROCK2	7
BP	GO:1905820	positive regulation of chromosome separation	7/7096	11/18670	0.07685	0.2277	0.1698	NSMCE2/ESPL1/ANAPC5/DLGAP5/ANAPC4/RB1/ANAPC11	7
BP	GO:0006352	DNA-templated transcription, initiation	106/7096	249/18670	0.07739	0.2291	0.1708	VDR/CDKN1A/NR4A2/NOTCH2/RBPJ/DR1/THRA/PPARD/CBFB/MED10/KAT2B/THRAP3/NOTCH3/RRN3P1/CDK4/ZNF451/NR3C2/NR1H2/SRF/GTF2E1/PPM1D/CCNH/TAF11/PSMC4/MED15/NR1D2/TAF12/GTF2F2/MITF/POLR2L/HMGB1/SUB1/MED17/CREB1/MED27/CCND1/TAF1B/CDK9/TAF5/PPARGC1A/POLR2H/MED16/SETX/GTF2H4/MED13/PSMC3/RXRA/CAND1/BAX/PSMC6/NR2E3/NR1H3/RSF1/TAF1D/GTF2F1/POLR1C/MED4/TEAD2/POLR2F/MED30/POLR2D/TAF6L/MED25/PPARA/TBPL1/HEY2/GTF2A1/POLR2K/GTF3C3/NOTCH4/ERCC2/TAF9B/CCNC/HNF1B/TAF4/RORA/BCLAF1/FOSL1/HNF1A/TAF1C/NR4A3/MED8/MAZ/BDP1/NR2F1/PSMC5/NRBP1/ESRRB/PSMC2/SMARCA5/NR2E1/POLRMT/MED24/TBP/CD3EAP/MED26/NRBF2/NR2C2/PAXIP1/POLR2I/WNT10B/NR2C2AP/NR1H4/NR2F6/TAF7/GTF2I	106
BP	GO:0071560	cellular response to transforming growth factor beta stimulus	106/7096	249/18670	0.07739	0.2291	0.1708	FOS/FYN/CX3CR1/SKIL/APPL2/ACVR2B/SKI/ARHGEF18/WNT5A/FAM89B/ITGB5/SMAD5/SMAD7/RNF111/SMAD2/F11R/NREP/PBLD/LDLRAD4/ZBTB7A/TGFB1/ZNF451/HPGD/MAPK7/COL4A2/HYAL2/HSPA5/CDKN2B/USP9X/PMEPA1/LTBP3/FURIN/NLK/CDKN1C/SDCBP/CHST11/PML/CREB1/CRK/SIRT1/ACVR1B/CDH5/PPARGC1A/CITED2/FLCN/BCL9L/PDCD5/PEG10/PTK2/ZYX/WWOX/SNX6/HDAC2/BMPR1A/TAB1/STRAP/DNM2/ZNF703/MTMR4/LRG1/EID2/HTRA1/UBC/RASL11B/ITGA3/STUB1/PXN/ADAM17/CAV3/WFIKKN1/ADAM9/TRIM33/WNT1/LTBP4/ZFP36L2/ITGA8/TGFB3/TGFB1I1/PIN1/GCNT2/SPINT3/LEMD3/HSP90AB1/CILP/MEN1/SOX5/GLG1/PRKCZ/RHOA/LIMS1/ENG/WNT10A/HTRA4/WNT7A/APPL1/STK16/BMPR1B/AMHR2/TWSG1/VEPH1/PDGFD/CD109/MEF2C/FOXH1/BMPR2/GDF5	106
BP	GO:1905475	regulation of protein localization to membrane	81/7096	187/18670	0.07753	0.2294	0.171	ITGAM/FYN/EZR/STX7/PLS1/ARF6/CSK/GBP1/RAB11A/CHP1/PMAIP1/CIB1/YWHAH/SQSTM1/TNF/SLC7A11/C2CD5/EPHB2/ACTB/TGFB1/MIEF1/FIS1/GRIPAP1/PAK1/RHOG/FZD9/GOPC/CDK5/SFN/HRAS/CASP8/GDI1/NUMB/CNST/RAP1A/LRP1/SPTBN1/MYO1C/PDCD5/MAPK8/BCL2/INPP5K/GZMB/RHOQ/GRASP/CNPY4/RANGRF/NKD2/YWHAQ/ITGA3/MMP14/DMTN/CEMIP/EGFR/CRIPT/IQSEC2/STAC2/GPC2/PID1/YWHAE/VTI1B/BAD/TREM2/IFNG/PPP1R13B/STX8/KIF5B/CACNB3/YWHAG/AP2M1/PRKCZ/GPC4/DAG1/CLIP3/ITGB1BP1/SSH1/RER1/LRP4/PICALM/APPL1/ZMYND8	81
BP	GO:0051303	establishment of chromosome localization	35/7096	75/18670	0.07766	0.2297	0.1712	NUP62/RAB11A/SPDL1/ACTR2/CHMP4B/PSRC1/MEI1/SEH1L/CENPE/CCDC155/SPAG5/MIS12/CDC23/CENPC/ATM/CHAMP1/SPICE1/NDC80/MLH1/CHMP2A/NDEL1/NUF2/ZW10/CHMP1A/VPS4B/ACTR3/DLGAP5/KIF2C/KATNB1/KPNB1/CHMP1B/UBE2B/RRS1/KIF14/BOD1	35
BP	GO:0031023	microtubule organizing center organization	59/7096	133/18670	0.07794	0.2304	0.1718	NUP62/ATF5/ODF2/PKD2/HAUS8/KAT2B/CHMP4B/TRIM37/KIF3B/CETN3/PCM1/CEP131/SASS6/UBXN2B/PLK2/NPM1/PAFAH1B1/CDK5RAP2/KIAA0753/NSFL1C/CEP76/CCDC78/CNTLN/BBS4/SYNE2/HAUS2/SPICE1/CHMP2A/BCAS3/CKAP5/SLC16A1/CEP152/NDEL1/GEN1/CHMP1A/VPS4B/PARD6B/CEP63/E2F4/CLASP2/BRCA1/CETN1/CETN2/HAUS5/CHORDC1/HAUS1/KAT2A/PKHD1/CEP120/AURKA/BRSK1/SAC3D1/UXT/CHMP1B/ROCK2/CEP85/C2CD3/ALMS1/CCNF	59
BP	GO:0010039	response to iron ion	17/7096	33/18670	0.07924	0.2325	0.1733	SLC40A1/HFE/HMOX1/CYBRD1/ALAD/HIF1A/MAP1LC3A/CPOX/ACO1/CCND1/G6PD/BCL2/PDX1/HAMP/MDM2/ATP7A/SNCA	17
BP	GO:0010591	regulation of lamellipodium assembly	17/7096	33/18670	0.07924	0.2325	0.1733	RAC2/TWF2/RAC1/DNM2/HDAC4/FER/DMTN/BIN3/SLIT2/FSCN1/WNT1/ATP7A/HRG/ARPC2/MTOR/WAS/NCKAP1	17
BP	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	17/7096	33/18670	0.07924	0.2325	0.1733	CDKN2D/CDKN1A/TNFAIP3/KAT2B/HEXIM1/LATS1/TFAP4/CEBPA/CDKN2B/CASP3/CDKN1C/HEXIM2/CDKN1B/CDKN2C/IPO7/LATS2/MEN1	17
BP	GO:0051204	protein insertion into mitochondrial membrane	17/7096	33/18670	0.07924	0.2325	0.1733	BMF/PMAIP1/YWHAH/SFN/CASP8/BCL2L11/MAPK8/BCL2/BAX/GZMB/OXA1L/YWHAQ/YWHAE/BAD/PPP1R13B/MOAP1/YWHAG	17
BP	GO:0071695	anatomical structure maturation	72/7096	165/18670	0.07924	0.2325	0.1733	IGF1/KLF2/CX3CR1/CDKN1A/NR4A2/RBPJ/WNT5A/S1PR1/DCHS1/THBS3/FAM210B/REC8/ZBTB7A/KCNIP2/HIF1A/PTK2B/MYO5A/LEP/FEM1B/BCL11A/B4GALT6/RYR1/BMP2/CDKN1C/XYLT1/SEMA4D/NSUN2/RFX3/CDH5/LRRK2/G6PD/EPHA8/TAL1/LYL1/BCL2/ANKRD17/LGI4/TYMS/B4GALT5/CLN5/CDK5R2/ARCN1/C1QL1/WNT1/ERCC2/MAP3K13/EPB42/TMEM79/TFCP2L1/RET/RB1/RXFP2/MMP2/MTOR/MBTPS2/RHOA/CDH3/AURKA/PICK1/APP/DAG1/SRRM4/CX3CL1/TRPC4AP/IRX5/TRIM58/WNT10B/GJA1/GREM1/NOM1/FOXO3/GLDN	72
BP	GO:0001919	regulation of receptor recycling	13/7096	24/18670	0.07925	0.2325	0.1733	ARAP1/ECE1/VAMP3/LAMTOR1/RAB29/KIF16B/TRAT1/INPP5F/ANXA2P2/PSEN1/OPTN/ANXA2/SNCA	13
BP	GO:0010288	response to lead ion	13/7096	24/18670	0.07925	0.2325	0.1733	PPP2CA/PTGS2/CDK4/ALAD/MAP1LC3A/CAT/CPOX/QDPR/SPARC/PPP1CA/DNMT3A/ATP7A/APP	13
BP	GO:0031579	membrane raft organization	13/7096	24/18670	0.07925	0.2325	0.1733	MYADM/S100A10/PACSIN2/CD2/FLOT1/PTPRC/FLOT2/EMP2/ABCA7/CAV3/ANXA2P2/ANXA2/RFTN1	13
BP	GO:0033081	regulation of T cell differentiation in thymus	13/7096	24/18670	0.07925	0.2325	0.1733	SOD1/EGR3/PTPN2/ADAM8/IL7R/NFKBID/RASGRP1/CLPTM1/TESPA1/VNN1/BMP4/ADA/FOXN1	13
BP	GO:0034162	toll-like receptor 9 signaling pathway	13/7096	24/18670	0.07925	0.2325	0.1733	MYD88/TNIP2/GRAMD4/IRAK4/TRAF6/RSAD2/HMGB1/RAB7B/TLR8/HAVCR2/RTN4/UNC93B1/NR1H4	13
BP	GO:0046135	pyrimidine nucleoside catabolic process	13/7096	24/18670	0.07925	0.2325	0.1733	TYMP/UPP1/NT5C/CDADC1/DPYD/APOBEC3G/APOBEC3C/APOBEC2/APOBEC3B/CDA/NT5C3A/NT5M/UPP2	13
BP	GO:0046475	glycerophospholipid catabolic process	13/7096	24/18670	0.07925	0.2325	0.1733	ENPP2/GDE1/ABHD12/GPCPD1/APOC1/SCARB1/PNPLA6/PLA2G15/LDLR/PNPLA8/PRDX6/INPP5F/ABHD16A	13
BP	GO:0050687	negative regulation of defense response to virus	13/7096	24/18670	0.07925	0.2325	0.1733	FGL2/NPLOC4/SEC14L1/TARBP2/HTRA1/PCBP2/C1QBP/MUL1/GPATCH3/RIOK3/NLRX1/TRAF3IP1/TSPAN6	13
BP	GO:0099563	modification of synaptic structure	13/7096	24/18670	0.07925	0.2325	0.1733	CTTNBP2/PFN1/GRIPAP1/STAU1/BAIAP2/ITSN1/ABL1/CAMKV/CYFIP1/FMR1/RHOA/DLGAP3/SYNPO	13
BP	GO:1901071	glucosamine-containing compound metabolic process	13/7096	24/18670	0.07925	0.2325	0.1733	NANP/PGM3/EXTL2/GNPDA1/NAGK/CHST2/RENBP/CHST5/CTBS/GNPNAT1/MGAT3/GNE/CHST7	13
BP	GO:1903010	regulation of bone development	13/7096	24/18670	0.07925	0.2325	0.1733	SIGLEC15/NOTCH2/POR/ATP6AP1/FBXW7/LILRB1/TYROBP/CLDN18/CARM1/SLC9B2/TMEM119/GREM1/GHRL	13
BP	GO:1903421	regulation of synaptic vesicle recycling	13/7096	24/18670	0.07925	0.2325	0.1733	DNM3/SYT11/PLAA/PPP3CB/GRIPAP1/CDK5/LRRK2/CYFIP1/TOR1A/SH3GL1/DNM1/DNM1L/SNCA	13
BP	GO:0033627	cell adhesion mediated by integrin	32/7096	68/18670	0.07964	0.2335	0.1741	PTPN6/LYN/ITGA5/ITGB7/ITGB5/LPXN/CIB1/TESC/DPP4/CYP1B1/SWAP70/CXCL13/ITGA4/ITGA11/CCL5/P2RY12/CRK/EPHA8/PTK2/MUC1/SERPINE1/ITGA2/ADA/ADAM17/ADAM9/SKAP1/HRG/RET/PIK3CG/ITGB1BP1/IFT74/CD3E	32
BP	GO:0006606	protein import into nucleus	63/7096	143/18670	0.08021	0.2351	0.1753	CDKN1A/APPL2/TXNIP/LMNA/STAT3/NUP62/IPO13/PTGS2/CHP1/FLNA/NUP214/NFKBIA/TNPO1/RAN/HCLS1/TGFB1/RAB23/NUP85/NXT1/CBLB/CD36/LEP/PRKCD/PTTG1IP/HYAL2/KPNA4/ZPR1/SNUPN/UBR5/MMP12/MDFIC/POM121/PML/MAVS/LRRK2/NOLC1/IPO4/BMP4/NUP88/CSE1L/NUP107/NXT2/NUP93/IPO9/PSEN1/IPO7/MAPK1/KPNA1/NUP50/IFNG/ARNTL/CHP2/TNPO3/RANBP6/NPAP1/PKIA/SPRN/MBTPS1/KPNB1/APPL1/SMO/TARDBP/POM121C	63
BP	GO:0033044	regulation of chromosome organization	143/7096	342/18670	0.08028	0.2352	0.1753	DUSP1/SPI1/PINK1/MAD2L2/SKI/MAP1S/LMNA/BCL6/PHF19/DYNC1LI1/CHTOP/MYC/MCM2/UBE2N/SENP6/ZNF304/PAF1/SPDL1/ERCC4/MAP3K4/TGFB1/SMC5/SIN3A/ZNF451/ARRB1/MORC2/PKIB/RUVBL2/CENPE/NAF1/NSD1/NAA10/ZBTB7B/KAT7/RMI2/SETMAR/HNRNPA1/VEGFA/SETD5/KLHL22/HNRNPA2B1/CDK5RAP2/IL1B/NSMCE2/XRCC5/HMGA1/UBR5/MIER1/DCP2/PML/SIRT1/SFPQ/NAA40/SETD7/PAXBP1/CDK9/LRRK2/PPARGC1A/CDC23/FLCN/BCOR/TAL1/ESPL1/NAT10/ZNF207/LCMT1/ATM/ANAPC5/BUB3/MUC1/MAPKAPK5/KMT2E/AKAP8/MAPK8/HNRNPC/NDC80/XRN1/PRKD2/XRCC1/NOC2L/ERCC1/CTCF/TLK1/ATAD2B/SETDB1/GEN1/ZW10/HNRNPD/LIG4/CCT4/ZMPSTE24/KDM4D/MOS/RNF20/FBXO4/CDC26/CAMK2D/CCT8/BRCA1/ATR/USP7/RIOK2/KAT2A/FMR1/MAPK1/DLGAP5/RTEL1/ACD/CTC1/ANAPC4/EID1/MKI67/ASF1A/CDC27/OGT/CDC20/RNF4/GNL3L/PCID2/RB1/JDP2/SET/KMT2B/PRKCQ/ANAPC11/SNCA/POT1/PAX7/PAX5/IK/GCG/TADA3/PAXIP1/UBE2B/GNL3/PNKP/FEN1/NEK7/TOP2A/TET1/UPF1/TAF7/ZNF335	143
BP	GO:0070371	ERK1 and ERK2 cascade	133/7096	317/18670	0.08099	0.2372	0.1768	KLF4/IGF1/FPR2/HTR2B/NOD2/FN1/GLIPR2/EZR/PTGER4/PTPN6/DUSP1/DUSP6/LYN/NOTCH2/CSK/GBP1/GPNMB/ATP6AP1/RAP1B/FLT1/PTPN2/MARCO/DUSP10/MIF/MAP2K1/CIB1/FBXW7/ACKR3/CD44/MYC/NLRP12/GSTP1/PTPRC/RRAS/TNF/CD74/EPHB2/APOE/HMGCR/SLAMF1/DUSP3/NDRG2/TGFB1/ARRB1/APIP/RAPGEF2/CD36/PTK2B/RANBP9/P2RY6/TLR4/PTPN22/FLT3/PDGFC/BMP2/HRAS/ABL1/IL1B/AGER/CCL5/MAP3K12/RASGRP1/RAP1A/SHC1/LRP1/HMGB1/TNFRSF11A/CCL7/NPTN/MFHAS1/CHI3L1/PDGFB/FLCN/DUSP4/CCL13/NRP1/PRKD2/GNAI2/CCL8/BMP4/TNIP1/RGS14/CHRNA10/FFAR4/MAP2K2/LGALS9/PDGFA/BTN2A2/PRMT5/SPRY1/F2R/ABCA7/SPRED1/EGFR/CCL20/CCL26/SPRY2/MAPK1/HCRTR1/ZFP36L2/TREM2/HAVCR2/EPHB1/PIN1/GCNT2/PKHD1/CD4/FSHR/PRKCZ/CSF1R/TRPV4/C5AR2/PDE8A/APP/GPR183/CX3CL1/ITGB1BP1/CCL19/TIRAP/SLC30A10/GCG/CCL4/CCR7/FGF23/IL26/CCL24/HMGB4/PRKCA/SERPINF2/P2RY1/PDGFD/THPO/WNK2	133
BP	GO:0006289	nucleotide-excision repair	49/7096	109/18670	0.08176	0.2392	0.1783	USP45/RNF111/HUS1B/RAD23B/ERCC6/ERCC4/NEIL2/ZNF830/RPA1/DDB1/CCNH/POLD4/POLD2/POLR2L/SIRT1/POLR2H/RFC3/GTF2H4/ISY1/RAD52/PCNA/XRCC1/ERCC1/UBC/LIG4/POLR2F/POLR2D/ATXN3/POLL/COPS2/CETN1/CETN2/USP7/POLR2K/DDB2/ERCC2/POLD1/CUL4B/PRPF19/LIG3/COPS8/GPS1/RBX1/AQR/SLC30A9/POLR2I/COPS3/PNKP/ERCC8	49
BP	GO:0021761	limbic system development	49/7096	109/18670	0.08176	0.2392	0.1783	ATP2B4/TSC1/SRD5A1/ALK/EZH2/GSK3B/ZEB2/BTG2/ANXA3/LRP8/SRF/XRN2/EIF2B5/CDK5/CASP3/PAFAH1B1/RAB3GAP1/BBS2/CRK/MKKS/ETS1/BBS4/MFSD2A/DCLK2/NRP1/XRCC1/BAX/NRP2/NME1/DAB1/BCAN/UQCRQ/KDM6B/CDK5R2/YWHAE/HTR5A/PLXNA3/NR4A3/KIF5B/EIF2B3/PHLPP2/NR2E1/RELN/EZH1/LMX1A/FGF13/OTP/SMO/KIF14	49
BP	GO:0006734	NADH metabolic process	20/7096	40/18670	0.08196	0.2396	0.1786	HK3/PGK1/MDH1/PFKM/PFKP/GAPDH/PGAM1/PKM/TPI1/ALDOC/ENO1/ALDOA/GPI/SLC25A12/MDH1B/FOXK2/ENO2/VCP/ADPGK/PFKL	20
BP	GO:0021532	neural tube patterning	20/7096	40/18670	0.08196	0.2396	0.1786	TCTN1/PRKACB/TULP3/ARL13B/WDR19/ATP6AP2/GORAB/BMP4/KDM2B/PRKACA/MKS1/HES1/WNT1/PSEN1/GPR161/TRAF3IP1/PAX7/TMEM107/SMO/PTCH1	20
BP	GO:0042133	neurotransmitter metabolic process	67/7096	153/18670	0.08214	0.24	0.1789	KLF4/NQO1/KLF2/CX3CR1/TLR2/ATP2B4/ACP5/GCH1/CLEC7A/POR/ARG2/SRD5A1/ALDH9A1/PTGS2/ALDH7A1/JAK2/TNF/DDAH2/HNMT/PKD2/TICAM1/CYP1B1/CD36/PTK2B/INSR/HBB/PTX3/TLR4/MAOA/DPYD/IL1B/AIF1/CLN3/AASDH/CLU/RAC1/GLA/ALDH5A1/SPR/DAGLB/SHMT2/DNM2/CD47/BHMT/CHKA/AGXT2/SHMT1/TPH2/MAOB/AMT/RORA/IFNG/ATP7A/SLC7A2/CD34/HSP90AB1/DBH/WDR35/MTOR/LRTOMT/CHAT/SLC25A32/CHDH/ROCK2/PHGDH/TLR6/GCHFR	67
BP	GO:0043392	negative regulation of DNA binding	26/7096	54/18670	0.08243	0.2407	0.1795	MAD2L2/FBXW7/PER2/JAK2/NFKBIA/HMOX1/ERCC4/SIN3A/ENHO/TFAP4/HABP4/SP100/GZMA/ZNF593/HEY1/SUMO1/SRI/HDAC2/ID2/ZFP90/RSF1/HEY2/CPNE1/PSEN1/MSX1/SMO	26
BP	GO:0051208	sequestering of calcium ion	58/7096	131/18670	0.08272	0.241	0.1797	SLC8A1/HTR2B/PTPN6/LYN/MCOLN1/TPCN1/DIAPH1/CXCL9/CXCL11/PTPRC/P2RX7/CXCL10/PKD2/TGFB1/ITPR1/PTK2B/MYO5A/CORO1A/P2RY6/RYR1/ABL1/GSTO1/PLCG2/DMD/ATP7B/TRPM2/LCK/CCR5/SRI/RASA3/ANXA6/BAX/PRKACA/CYBA/MCOLN2/F2R/CALR/CAMK2D/PLCB1/CEMIP/HSP90B1/LETM1/CASQ1/CAPN3/CASQ2/HRC/BDKRB1/TMEM38B/LACRT/LIME1/SNCA/CX3CL1/CCL19/CHERP/ATP1A2/CCR7/MCOLN3/NTSR1	58
BP	GO:0055076	transition metal ion homeostasis	58/7096	131/18670	0.08272	0.241	0.1797	S100A9/S100A8/EPAS1/SLC40A1/SCO2/SLC11A1/SOD1/ATP6AP1/SLC25A37/NCOA4/CUL1/STEAP4/MYC/HFE/SLC31A2/HMOX1/SLC25A28/ATOX1/FBXL5/TMC8/CYBRD1/HIF1A/FTL/ISCU/COX19/STEAP3/HYAL2/ABCB6/TTC7A/ATP6V1A/SLC39A10/SLC39A8/ACO1/ATP7B/SLC39A13/LCK/BDH2/SLC39A7/SRI/ARF1/GLRX3/CAND1/SLC46A1/IREB2/SLC39A12/CUTC/COMMD1/TFRC/HAMP/EIF2AK1/EPB42/ATP7A/SLC30A2/APP/XIAP/SLC30A9/PICALM/ABCB7	58
BP	GO:1902850	microtubule cytoskeleton organization involved in mitosis	58/7096	131/18670	0.08272	0.241	0.1797	SUN2/STMN1/NUP62/RAB11A/FLNA/SPDL1/RAN/CHMP4B/PSRC1/KIF3B/MAP4/CENPE/UBXN2B/PLK2/PAFAH1B1/CDK5RAP2/SAPCD2/NSFL1C/ARHGEF2/KIF4A/KIF2A/RCC1/ESPL1/ZNF207/SPICE1/BCCIP/NDC80/PARP3/CHMP2A/DCTN2/NDEL1/NUF2/NUSAP1/ZW10/CHMP1A/VPS4B/SPRY1/TUBG2/CLASP2/GPSM2/SPRY2/SMC3/SPC25/CENPA/CDC20/STAG1/TBCE/VCP/MISP/RHOA/AURKA/KPNB1/EFHC1/MSTO1/CHMP1B/AAAS/PRC1/WRAP73	58
BP	GO:0002832	negative regulation of response to biotic stimulus	23/7096	47/18670	0.0828	0.241	0.1797	ARG2/TNFAIP3/FGL2/LILRA2/MAPKBP1/CACTIN/NPLOC4/SEC14L1/TARBP2/SIGLEC11/HTRA1/PCBP2/C1QBP/MUL1/GPATCH3/RIOK3/SIGIRR/HAVCR2/NLRX1/LACRT/TRAF3IP1/TSPAN6/FAM3A	23
BP	GO:0021695	cerebellar cortex development	23/7096	47/18670	0.0828	0.241	0.1797	DLL1/NAGLU/MAP2K1/LDB1/EZH2/HSPA5/CDK5/OPHN1/CLP1/UQCRQ/ARCN1/CBLN1/RORA/FAIM2/ATP7A/SPTBN2/KNDC1/TTBK2/TRNP1/WNT7A/AGTPBP1/SMO/KIF14	23
BP	GO:0047496	vesicle transport along microtubule	23/7096	47/18670	0.0828	0.241	0.1797	BLOC1S2/KIF3B/KIFAP3/AP3M2/TRAK2/PAFAH1B1/DTNBP1/CLN3/RASGRP1/BLOC1S6/BLOC1S3/NDEL1/KIF13A/BLOC1S1/BLOC1S4/AP3B1/KIF1B/AP3M1/KIF5B/TRAK1/PRKCZ/KIF1C/TRIM46	23
BP	GO:0061383	trabecula morphogenesis	23/7096	47/18670	0.0828	0.241	0.1797	SLC40A1/SBNO2/RBPJ/S1PR1/THBS3/UBE4B/HEG1/SRF/NRG1/SEMA4D/HEY1/BMP7/BMP5/BMPR1A/CAV3/HEY2/MMP2/RHOA/ENG/WNT10B/GREM1/RBP4/FOXH1	23
BP	GO:0060402	calcium ion transport into cytosol	69/7096	158/18670	0.08298	0.2414	0.18	SLC8A1/HTR2B/FYN/PTPN6/ATP2B4/LYN/MCOLN1/TPCN1/DIAPH1/TMBIM6/CXCL9/CXCL11/PTPRC/P2RX7/CXCL10/PKD2/TGFB1/ITPR1/PTK2B/MYO5A/CORO1A/P2RY6/RYR1/ABL1/GSTO1/PLCG2/PML/DMD/TRPM2/LCK/CCR5/SRI/RASA3/BCL2/BAX/MS4A1/PRKACA/CYBA/MCOLN2/F2R/GRIN2C/CAMK2D/PLCB1/CEMIP/LETM1/CASQ1/CAPN3/CASQ2/HRC/BDKRB1/CD4/TMEM38B/LACRT/CACNB3/LIME1/SNCA/CX3CL1/P2RX2/CCL19/BAK1/CHERP/ATP1A2/CCR7/SLC8A3/MCOLN3/FAM155A/ADCYAP1R1/NTSR1/P2RX5	69
BP	GO:0090630	activation of GTPase activity	44/7096	97/18670	0.08308	0.2416	0.1801	SIPA1L1/WNT5A/TSC1/NEDD9/ADPRH/RABGAP1L/TBC1D15/TBC1D5/PTK2B/SGSM1/TBC1D1/RHOG/CXCL13/ABR/RASGRP1/TBC1D2/RABGAP1/CRK/TBCK/TBC1D12/BCR/RALGAPB/TBC1D17/TBC1D9B/TBC1D13/BCAS3/TBC1D8/NDEL1/TBC1D8B/TBC1D7/EIF5/TBC1D22A/CORO1C/RASGRF1/RCC2/RUNDC1/TBC1D21/EVI5/TBC1D10C/RALGAPA2/GRTP1/CCR7/SYDE1/TBC1D10B	44
BP	GO:0006283	transcription-coupled nucleotide-excision repair	34/7096	73/18670	0.08331	0.2421	0.1805	ERCC6/ERCC4/ZNF830/RPA1/DDB1/CCNH/POLD4/POLD2/POLR2L/POLR2H/RFC3/GTF2H4/ISY1/PCNA/XRCC1/ERCC1/UBC/POLR2F/POLR2D/COPS2/USP7/POLR2K/ERCC2/POLD1/CUL4B/PRPF19/LIG3/COPS8/GPS1/RBX1/AQR/POLR2I/COPS3/ERCC8	34
BP	GO:0006801	superoxide metabolic process	34/7096	73/18670	0.08331	0.2421	0.1805	NQO1/ITGAM/FPR2/ACP5/GCH1/BST1/CLEC7A/SOD1/GNAI3/CYB5R4/GSTP1/TNF/SH3PXD2A/TGFB1/CD36/PRDX1/NCF4/PRKCD/NCF2/NCF1/TYROBP/BMP7/NOXA1/IMMP2L/AATF/GNAI2/CYBA/CYBB/NFE2L2/DHFR/EGFR/PREX1/ATP7A/MPO	34
BP	GO:0005976	polysaccharide metabolic process	51/7096	114/18670	0.08348	0.2424	0.1807	IGF1/EXTL2/MANBA/NDST2/HS2ST1/MGAM/B3GNT8/PER2/EXT2/EXT1/NFKB1/GSK3B/AGL/DYRK2/TGFB1/B3GNT2/PPP1R3E/INSR/GYS1/PPP1R3D/GYG2/CSGALNACT1/B3GNT5/PPP1R2/PHKB/IL6ST/IRS2/PDGFB/PCDH12/PHKG1/PGM2/PRKAG2/KHK/INPP5K/PPP1R3B/NDST1/PPP1R3F/CSGALNACT2/B4GALT5/AP2A1/PPP1CC/PPP1CA/B3GNT4/GAA/PYGM/PPP1CB/PYGL/ESRRB/MTOR/G6PC/CHST7	51
BP	GO:0015749	monosaccharide transmembrane transport	51/7096	114/18670	0.08348	0.2424	0.1807	IGF1/PEA15/APPL2/SLC5A3/MEF2A/TSC1/SLC23A2/PPARD/PPBP/SLC45A3/SLC2A3/SLC2A6/TNF/C2CD5/SLC2A9/SLC2A8/LEP/INSR/IL1B/RAP1A/CREBL2/IRS2/RTN2/ITLN1/CLTCL1/GRB10/PRKAG2/INPP5K/RHOQ/FFAR4/RNASEL/SLC50A1/SLC5A4/NFE2L2/FABP5/ASPSCR1/ADIPOR2/PID1/SLC2A10/HNF1A/NR4A3/TERT/STXBP3/SLC5A10/CLIP3/SLC5A9/APPL1/SLC5A2/KLF15/STXBP4/SESN2	51
BP	GO:0072384	organelle transport along microtubule	39/7096	85/18670	0.08372	0.2429	0.1811	SUN2/MAP1S/BLOC1S2/UCHL1/LAMP1/KIF3B/KIFAP3/HIF1A/BICD2/AP3M2/TRAK2/PAFAH1B1/DTNBP1/CLN3/RHOT2/RASGRP1/BLOC1S6/BICD1/SYNE2/TMEM201/BLOC1S3/COPG2/NDEL1/KIF13A/BLOC1S1/BLOC1S4/PEX14/AP3B1/KIF1B/AP3M1/KIF5B/TRAK1/PRKCZ/MREG/KIF1C/TRIM58/UXT/MGARP/TRIM46	39
BP	GO:0031214	biomineral tissue development	71/7096	163/18670	0.08375	0.2429	0.1811	IGF1/SLC8A1/FAM20A/ACVR2B/SBNO2/GPNMB/KLF10/PTGS2/SPP1/S1PR1/SNX10/ATRAID/LGR4/CEBPB/P2RX7/ATF4/TGFB1/HIF1A/PTK2B/LEP/ROR2/TCIRG1/FZD9/FGR/BMP2/LTBP3/TUFT1/ISG15/CNNM4/HEY1/TRPM4/BMP7/BCOR/KLK4/BMPR1A/BMP4/ADRB2/ASGR2/ZMPSTE24/WDR72/SLC20A1/PPARA/HEY2/ANXA2P2/KL/SRGN/CYP27B1/MINPP1/ERCC2/TGFB3/AMBN/BMP2K/PTHLH/MGP/TMEM38B/DSPP/ANXA2/WNT6/IBSP/ITGB1BP1/NBR1/ROCK2/TMEM119/FGF23/WNT10B/CER1/GJA1/GREM1/BMPR1B/MEF2C/BMPR2	71
BP	GO:0001952	regulation of cell-matrix adhesion	53/7096	119/18670	0.08504	0.2462	0.1835	S100A10/BST1/TSC1/BCL6/CIB1/LDB1/SLC9A1/GSK3B/DUSP3/PEAK1/CD36/PTK2B/ADAM15/NINJ1/VEGFA/ABL1/MMP12/LRP1/PPM1F/SLK/RAC1/PTK2/ARHGAP6/LIMCH1/EMP2/NRP1/DISC1/BCL2/WDPCP/SERPINE1/BCAS3/MMP14/DMTN/CORO1C/CLASP2/RCC2/SKAP1/HRG/PRKCZ/MAP4K4/RHOA/LIMS1/DAG1/CX3CL1/ITGB1BP1/CCR7/CD3E/ROCK2/HOXA7/MACF1/PIK3CB/PTPRJ/FMN1	53
BP	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	12/7096	22/18670	0.08553	0.2462	0.1835	KRI1/ABT1/RPS21/EXOSC2/FTSJ3/EXOSC7/RCL1/ERI3/EXOSC9/EXOSC3/EXOSC8/RRS1	12
BP	GO:0000469	cleavage involved in rRNA processing	12/7096	22/18670	0.08553	0.2462	0.1835	KRI1/ABT1/RPS21/NHP2/EXOSC2/EXOSC7/RCL1/ERI3/EXOSC9/EXOSC3/EXOSC8/RRS1	12
BP	GO:0005980	glycogen catabolic process	12/7096	22/18670	0.08553	0.2462	0.1835	AGL/PPP1R3D/PHKB/PHKG1/PGM2/PPP1R3B/PPP1CA/GAA/PYGM/PPP1CB/PYGL/G6PC	12
BP	GO:0006312	mitotic recombination	12/7096	22/18670	0.08553	0.2462	0.1835	ERCC4/SMC5/SMC6/TEP1/NSMCE2/RAD52/MLH1/XRCC1/ERCC1/RAD54B/GEN1/ERCC2	12
BP	GO:0006582	melanin metabolic process	12/7096	22/18670	0.08553	0.2462	0.1835	WNT5A/SLC7A11/ZEB2/RAPGEF2/MYO5A/ASIP/BCL2/DCT/CDH3/OCA2/APPL1/CTNS	12
BP	GO:0006783	heme biosynthetic process	12/7096	22/18670	0.08553	0.2462	0.1835	FECH/UROD/ALAD/CPOX/TMEM14C/SRRD/COX15/IREB2/NFE2L1/ALAS1/SLC25A38/SLC25A39	12
BP	GO:0032069	regulation of nuclease activity	12/7096	22/18670	0.08553	0.2462	0.1835	TMBIM6/OASL/PRKCD/OAS3/NPM1/DFFA/GZMA/OAS2/HMGB1/SIRT1/PCNA/HMGB2	12
BP	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	12/7096	22/18670	0.08553	0.2462	0.1835	VPS37B/PLAA/TOM1L1/VPS37C/RNF115/NEDD4/RNF126/TSG101/UBAP1/VPS4B/VPS25/UBAP1L	12
BP	GO:0045649	regulation of macrophage differentiation	12/7096	22/18670	0.08553	0.2462	0.1835	PTPN2/HCLS1/TGFB1/ROR2/CASP8/ID2/INHBA/FADD/C1QC/RB1/INHA/PRKCA	12
BP	GO:0051000	positive regulation of nitric-oxide synthase activity	12/7096	22/18670	0.08553	0.2462	0.1835	HTR2B/GCH1/SCARB1/TNF/KRAS/APOE/HIF1A/PTK2B/FCER2/DHFR/NUS1/TERT	12
BP	GO:0060390	regulation of SMAD protein signal transduction	12/7096	22/18670	0.08553	0.2462	0.1835	FAM89B/TOB1/PBLD/TGFB1/SPTBN1/BMPR1A/BMP4/NUP93/TGFB3/CILP/VEPH1/GDF5	12
BP	GO:0072643	interferon-gamma secretion	12/7096	22/18670	0.08553	0.2462	0.1835	CD2/LILRB1/TCIRG1/PTPN22/ABL1/RASGRP1/ISG15/BTN3A2/LGALS9/BTN3A1/CD244/NR1H4	12
BP	GO:0010458	exit from mitosis	16/7096	31/18670	0.08575	0.2462	0.1835	RGCC/CHMP4B/TGFB1/UBE2S/SIRT7/CDKN1C/CTDP1/CDC23/PPP2R2D/CHMP2A/CDKN1B/MAD2L1BP/ZW10/UBE2C/CLASP2/RPL24	16
BP	GO:0033198	response to ATP	16/7096	31/18670	0.08575	0.2462	0.1835	SLC8A1/SOD1/PTGS2/P2RX7/PANX1/IL1B/P2RY12/TRPM4/P2RX1/HSP90B1/P2RY4/P2RX2/CIB2/SSH1/P2RY1/P2RX5	16
BP	GO:0034661	ncRNA catabolic process	16/7096	31/18670	0.08575	0.2462	0.1835	DIS3L/SND1/DEDD2/SLFN13/XRN1/EXOSC2/EXOSC7/DIS3L2/EXOSC9/EXOSC3/DROSHA/EXOSC6/PNPT1/EXOSC8/NUDT16/EXOSC5	16
BP	GO:0042168	heme metabolic process	16/7096	31/18670	0.08575	0.2462	0.1835	BLVRB/FECH/HMOX1/UROD/ALAD/CPOX/TMEM14C/SRRD/BDH2/COX15/AMBP/IREB2/NFE2L1/ALAS1/SLC25A38/SLC25A39	16
BP	GO:0043457	regulation of cellular respiration	16/7096	31/18670	0.08575	0.2462	0.1835	CBFA2T3/PINK1/PRELID1/HIF1A/ISCU/PPARGC1A/FLCN/SHMT2/CISD1/NOA1/DNAJC15/IFNG/VCP/TRPV4/SNCA/PNPT1	16
BP	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity	16/7096	31/18670	0.08575	0.2462	0.1835	CCND3/RGCC/PKD2/CCND2/PSRC1/CCND1/PDGFB/CDKN1B/CCNK/CDK5R2/EGFR/CCNY/ADAM17/CCNYL1/CCNT1/CCNYL2	16
BP	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process	16/7096	31/18670	0.08575	0.2462	0.1835	VCAN/CHSY1/CHST13/CSGALNACT1/CSPG4/CYTL1/XYLT1/CHST11/SLC35D1/B3GALT6/XYLT2/CSGALNACT2/BCAN/CHST12/B3GAT3/CHST7	16
BP	GO:0090075	relaxation of muscle	16/7096	31/18670	0.08575	0.2462	0.1835	SLC8A1/SOD1/ATP1A1/RGS2/PDE4B/TIFAB/SRI/ADORA2B/ATP1B1/CAMK2D/ATP2A2/HRC/KCNMA1/SLN/ATP1A2/P2RY1	16
BP	GO:1902186	regulation of viral release from host cell	16/7096	31/18670	0.08575	0.2462	0.1835	TRIM32/TRIM13/VPS37B/CHMP4B/TRIM26/DDB1/PML/TRIM11/TRIM21/CHMP2A/TSG101/VPS4B/MID2/SMC3/TRIM15/PC	16
BP	GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II	16/7096	31/18670	0.08575	0.2462	0.1835	FOS/SPI1/STAT3/RELA/TGFB1/HIF1A/SRF/BMP2/PDGFB/BMPR1A/KLF5/SREBF2/TERT/GNL3/WT1/APLN	16
BP	GO:0000070	mitotic sister chromatid segregation	66/7096	151/18670	0.0869	0.2494	0.1859	DUSP1/MAD2L2/NUP62/RAB11A/DYNC1LI1/SPDL1/RAN/CHMP4B/PSRC1/SMC5/SEH1L/PDS5A/CENPE/NAA10/KLHL22/CDK5RAP2/DSCC1/NSMCE2/KIF4A/SPAG5/MIS12/CDC23/ESPL1/ZNF207/CENPC/LCMT1/SMC2/ATM/ANAPC5/CHAMP1/NCAPD3/BUB3/PHF23/AKAP8/NDC80/CHMP2A/DSN1/NUF2/GEN1/NUSAP1/INCENP/ZW10/CHMP1A/VPS4B/CENPK/TUBG2/CDC26/RIOK2/DLGAP5/KIF2C/KATNB1/ANAPC4/DIS3L2/CDC27/CDC20/PCID2/RB1/ANAPC11/IK/KPNB1/MSTO1/CHMP1B/RRS1/KIF14/BOD1/PRC1	66
BP	GO:0062014	negative regulation of small molecule metabolic process	48/7096	107/18670	0.08709	0.2498	0.1862	CBFA2T3/ATP2B4/APPL2/FBP1/SOD1/STAT3/SIRT4/SIK1/APOC1/NUPR1/AKR1C3/NFKB1/APOE/TGFB1/ERLIN1/BMP2/ERLIN2/ACACB/SIRT1/DGAT2/PPARGC1A/FLCN/SLC25A12/MYOG/BMP5/PFKFB1/SCAP/HDAC4/PLEK/DDIT4/ACADVL/AP2A1/SERPINA12/INSIG1/MST1/BRCA1/PPARA/DNAJC15/PID1/CYP27B1/SNAI1/CDA/RHOA/SNCA/ATCAY/NR1H4/C1QTNF3/FAM3A	48
BP	GO:0015711	organic anion transport	198/7096	482/18670	0.08738	0.2505	0.1868	SLCO4A1/SLC27A1/APBA1/SLC43A2/KCNN4/ANXA1/SLC19A2/PLA2G12A/SLC27A3/SLC38A6/ABCC5/FABP4/AQP9/SLC11A1/ATP8B2/SLC36A1/SLC23A2/SLCO3A1/ATP8A1/SLC25A19/SLC37A2/NPC2/PPARD/SLC25A25/MIF/SLC33A1/PITPNA/CYB5R1/RGS2/SLC25A20/SLC38A7/PLIN2/FOLR2/PER2/APOC1/SCARB1/SLC37A4/CYB5R4/SLC2A6/PSAP/P2RX7/SLC7A11/SLC2A9/SCP2/CETP/APOE/PRELID1/SLCO2B1/CA5B/SLC2A8/CPT2/STXBP1/CLN8/SLC7A7/UNC13B/ARL6IP1/STARD10/ABCD3/CD36/LEP/PITPNM1/PRKCD/SLCO4C1/HBB/SLC7A6/MFSD10/PRAF2/ATP11B/SLC7A5/SLC16A10/ACSL4/AKR1C1/SLC1A4/ATP10A/RAB3GAP1/ABCA1/IL1B/CLN3/LDLR/C2CD2L/SLC25A10/SLC35B4/SLC27A2/MPC2/ACACB/SLC35D1/ATP8B1/TNFRSF11A/SLC22A12/STARD7/SLC43A1/SLC25A15/LRRC8D/FABP3/IRS2/SLC25A5/SLC38A1/APOA5/PNPLA8/SLC7A1/SLC16A6/SLC25A12/MFSD2A/SLC26A8/PLA2G3/PLEKHA8/PRKAG2/NCOR1/NMUR2/RXRA/SLC6A5/SLC7A8/PPFIA4/SLC22A25/ABCG1/SLC16A2/SLC16A1/SFXN1/SLC46A1/CPT1A/OSBPL2/ABCB4/SLC10A1/SLC5A6/ABCB11/SLC4A5/NFKBIE/SLC13A2/GLS/GOT2/CPTP/SLC17A5/SLC35B1/SLC35A3/SLC26A4/SLC16A7/ABCA7/SLC36A4/NFE2L1/LRRC8A/PPARA/SLC25A13/NMB/SLC5A8/SLC35A5/PSEN1/SLC17A4/PRELID2/RAB3A/PLEKHA3/APOA1/PPFIA3/SLC4A7/SFXN5/SLC4A1/PLA2G6/SLC7A2/SLC25A24/SYT1/TMEM30A/ABCC3/ABCC4/CROT/SYT4/SLC6A13/TRIAP1/SLCO1C1/SNCA/SLC25A22/SLC25A32/OCA2/ABCD1/SFXN4/SLC25A38/SLC26A10/SLC35A2/SLC6A12/ATP1A2/SPX/LRRC8E/SLC38A5/SLC4A11/CTNS/GJA1/THRSP/SLC35D2/NR1H4/GLTP/SLC4A3/G6PC/SLC38A9/PLEKHA8P1/ATP10B/NTSR1/NTRK2/SLCO1B1/SLC16A5/STRA6	198
BP	GO:0070527	platelet aggregation	28/7096	59/18670	0.0875	0.2507	0.1869	PTPN6/CLIC1/MYL12A/LYN/FLNA/VCL/SLC7A11/ACTB/TLN1/STXBP1/HSPB1/PRKCD/HBB/TSPAN32/FIBP/RAP2B/P2RY12/MYH9/PLEK/DMTN/BLOC1S4/PIK3CG/STXBP3/CSRP1/PRKCQ/TYRO3/PRKCA/PIK3CB	28
BP	GO:2000756	regulation of peptidyl-lysine acetylation	28/7096	59/18670	0.0875	0.2507	0.1869	SPI1/TGFB1/SIN3A/ZNF451/ARRB1/RUVBL2/KAT7/SETD5/IL1B/SIRT1/PPARGC1A/FLCN/MUC1/HDAC2/NOC2L/CTCF/ZMPSTE24/BRCA1/HINT2/KAT2A/PRKAA1/EID1/SET/SNCA/SOX4/PAXIP1/KLF15/TAF7	28
BP	GO:1903038	negative regulation of leukocyte cell-cell adhesion	57/7096	129/18670	0.08778	0.2513	0.1874	KLF4/PTPN6/LILRB2/ANXA1/IRF1/ARG2/GPNMB/PTPN2/TNFRSF14/BCL6/SMAD7/FGL2/IL4R/CEBPB/CBFB/HFE/CD74/TNFRSF21/LILRB1/CXCL12/DUSP3/TGFB1/SOCS5/IL20RB/PTPN22/ZBTB7B/SOCS6/DTX1/CASP3/IDO1/NFKBID/HMGB1/HLA-G/CTLA4/GLMN/TIGIT/VSIG4/SCGB1A1/PDCD1LG2/NRARP/BMP4/LAG3/CD300A/CD274/LGALS9/LAX1/BTN2A2/HLX/PPARA/TNFSF4/PAG1/SOCS1/HAVCR2/CD80/TBX21/TWSG1/MIR146A	57
BP	GO:0090276	regulation of peptide hormone secretion	89/7096	208/18670	0.0881	0.2522	0.188	CRHBP/PPARD/HADH/SIRT4/ENY2/PER2/JAK2/FAM3D/HFE/TNF/HMGCR/DPP4/LRP5/PPP3CB/ITPR1/AACS/ARRB1/HIF1A/FFAR2/PIM3/ENHO/LEP/MCU/AIMP1/TCIRG1/ITSN1/PAX8/IL1B/UQCC2/CCL5/C2CD2L/RAP1A/MPC2/LRP1/RFX3/TRPM4/DOC2B/RAC1/GLUD1/KALRN/IRS2/SLC25A5/KLF7/SERP1/SRI/OXCT1/RPH3AL/GPR27/SLC16A1/SYTL4/CPT1A/PDX1/TM7SF3/PFKFB2/HMGN3/RAB8B/EGFR/ICA1/CLOCK/GIPR/TCF7L2/BAD/SYT9/PLA2G6/IFNG/ARNTL/KIF5B/NDUFAF2/MAP4K4/GHRH/SLC9B2/SOX4/SIDT2/ARL2BP/GCG/PFKL/NLGN2/GJA1/NR1H4/TARDBP/STXBP4/PRKCA/UCN3/RBP4/PSMD9/GHRL/KISS1/APLN/PHPT1	89
BP	GO:0006084	acetyl-CoA metabolic process	19/7096	38/18670	0.08866	0.2526	0.1883	PDK4/PDK2/HMGCS1/ACLY/GSTZ1/MPC2/ACACB/MLYCD/KYNU/PDK1/PDHB/DLAT/PDP2/NUDT7/PDHA2/PDP1/PDPR/TDO2/PIPOX	19
BP	GO:0007223	Wnt signaling pathway, calcium modulating pathway	19/7096	38/18670	0.08866	0.2526	0.1883	WNT5A/GNB1/AGO2/MOV10/PPP3CB/ROR2/NLK/PDE6G/GNG2/NFATC1/AGO1/TNRC6B/TNRC6A/FZD5/CAMK2A/PLCB1/FZD4/TCF7L2/FZD2	19
BP	GO:0015682	ferric iron transport	19/7096	38/18670	0.08866	0.2526	0.1883	ATP6V0D2/MCOLN1/ATP6AP1/STEAP4/ATP6V1C1/HFE/ATP6V0C/STEAP3/TCIRG1/ATP6V1A/ATP6V1G3/ATP6V1B2/ATP6V1D/DNM2/ATP6V0E2/ATP6V1G2/TFRC/LMTK2/ATP6V1B1	19
BP	GO:0015804	neutral amino acid transport	19/7096	38/18670	0.08866	0.2526	0.1883	SLC43A2/SLC36A1/RGS2/SLC38A7/LEP/SLC7A5/SLC1A4/SLC43A1/SLC38A1/SLC6A5/SLC7A8/SFXN1/NFKBIE/SLC36A4/NFE2L1/SLC25A38/SLC38A5/CTNS/SLC38A9	19
BP	GO:0045022	early endosome to late endosome transport	19/7096	38/18670	0.08866	0.2526	0.1883	EZR/WDR91/FAM160A2/MAP2K1/WDR81/RDX/ANKRD27/HOOK2/KIF16B/EMP2/HOOK3/RAB5A/MTMR2/MAP2K2/MAPK1/MSN/LMTK2/STX8/SNX16	19
BP	GO:0050892	intestinal absorption	19/7096	38/18670	0.08866	0.2526	0.1883	VDR/EZR/PLS1/F11R/SCARB1/LIMA1/CD36/LEP/AKR1C1/LDLR/ACO1/APOA5/SLC46A1/KCNQ1/UGCG/IREB2/HAMP/APOA1/EPB41	19
BP	GO:0071867	response to monoamine	19/7096	38/18670	0.08866	0.2526	0.1883	ATP2B4/SRD5A1/GNB1/SLC9A1/ATF4/SIN3A/PDE4B/ABL1/LRRK2/GNG2/PPARGC1A/HDAC2/DNM2/PRKACA/KCNQ1/MAPK1/NR4A3/APP/SNCA	19
BP	GO:0071869	response to catecholamine	19/7096	38/18670	0.08866	0.2526	0.1883	ATP2B4/SRD5A1/GNB1/SLC9A1/ATF4/SIN3A/PDE4B/ABL1/LRRK2/GNG2/PPARGC1A/HDAC2/DNM2/PRKACA/KCNQ1/MAPK1/NR4A3/APP/SNCA	19
BP	GO:0072512	trivalent inorganic cation transport	19/7096	38/18670	0.08866	0.2526	0.1883	ATP6V0D2/MCOLN1/ATP6AP1/STEAP4/ATP6V1C1/HFE/ATP6V0C/STEAP3/TCIRG1/ATP6V1A/ATP6V1G3/ATP6V1B2/ATP6V1D/DNM2/ATP6V0E2/ATP6V1G2/TFRC/LMTK2/ATP6V1B1	19
BP	GO:0097502	mannosylation	19/7096	38/18670	0.08866	0.2526	0.1883	TMTC3/POMGNT2/PIGV/ALG2/FKRP/SDF2L1/DPY19L4/PIGB/DPM1/TMTC2/ALG12/POMT1/NUS1/POMT2/DPM3/DPY19L2/DPY19L2P2/ALG8/ALG3	19
BP	GO:0045137	development of primary sexual characteristics	95/7096	223/18670	0.08878	0.2526	0.1883	WNT5A/SOD1/RETN/SRD5A1/NCOA4/FLNA/PLEKHA1/KITLG/LFNG/RDH10/CEBPB/LRRC6/NUPR1/AKR1C3/UBE3A/REC8/HMGCS1/UTF1/ARRB1/NUDT1/CTNNA1/SGPL1/ZNF830/LEP/ADAM15/INSR/PTX3/EIF2B5/HSPA5/VEGFA/CASP3/TNFSF10/WDR19/HSD17B4/IDH1/SIRT1/BASP1/EIF2S2/MKKS/CCND1/ACVR1B/CITED2/ASPM/ATM/PATZ1/IMMP2L/BCL2L11/MGST1/BCL2/TBC1D20/BAX/HMGB2/TIPARP/ERCC1/CASP2/NUP107/INHBA/CTSV/HYAL3/YBX3/MMP14/FZD4/SLIT2/CCDC182/FANCG/TAF4/RHOBTB3/HOXA10/LHFPL2/NASP/FSHR/TLR3/INHA/REN/RXFP2/WNT2B/KMT2B/FANCA/ZFP42/IRX5/MEA1/BCL2L2/EIF2B2/TFAP2C/CSDE1/GJA1/NRIP1/BMPR1B/ADCYAP1R1/AMHR2/MMP19/WT1/FOXO3/LHX9/SLIT3	95
BP	GO:0008645	hexose transmembrane transport	50/7096	112/18670	0.08882	0.2526	0.1883	IGF1/PEA15/APPL2/SLC5A3/MEF2A/TSC1/PPARD/PPBP/SLC45A3/SLC2A3/SLC2A6/TNF/C2CD5/SLC2A9/SLC2A8/LEP/INSR/IL1B/RAP1A/CREBL2/IRS2/RTN2/ITLN1/CLTCL1/GRB10/PRKAG2/INPP5K/RHOQ/FFAR4/RNASEL/SLC50A1/SLC5A4/NFE2L2/FABP5/ASPSCR1/ADIPOR2/PID1/SLC2A10/HNF1A/NR4A3/TERT/STXBP3/SLC5A10/CLIP3/SLC5A9/APPL1/SLC5A2/KLF15/STXBP4/SESN2	50
BP	GO:0017158	regulation of calcium ion-dependent exocytosis	50/7096	112/18670	0.08882	0.2526	0.1883	APBA1/RAP1B/SYT11/GSK3B/STXBP1/UNC13B/FBXL20/CDK5/RAB3GAP1/DTNBP1/RAP1A/DOC2B/PREPL/LRRK2/SYT6/ADCY1/ARF1/P2RX1/ADORA2B/RPH3AL/VPS18/NAPA/GNAI2/RAB5A/HYAL3/CAMK2A/CHRM2/DNM1L/CHRNA4/CDK5R2/SYT13/ATP2A2/DVL1/FMR1/RAB3A/CHRNB2/P2RY4/SYT9/SYT1/SYT2/VAMP1/STXBP3/DOC2A/SYT4/SYT5/SCAMP5/RIMS2/WNT7A/CACNA1H/P2RY1	50
BP	GO:0046580	negative regulation of Ras protein signal transduction	25/7096	52/18670	0.08888	0.2526	0.1883	STMN1/FBP1/NUP62/TIMP2/BCL6/EPHB2/KCTD10/HEG1/STMN3/RASA2/RASAL3/FLCN/RASA3/SCAI/KANK1/SYNGAP1/RABGEF1/ITGA3/SPRY1/ABL2/SPRY2/STAMBP/RASAL1/MAPKAP1/MET	25
BP	GO:0051438	regulation of ubiquitin-protein transferase activity	25/7096	52/18670	0.08888	0.2526	0.1883	PINK1/MAD2L2/SMAD7/ARRDC4/FBXW7/UBE2N/DCUN1D1/ARRDC3/UBE2S/FEM1B/ABL1/DTX3L/DCUN1D5/UBE2C/STUB1/DNM1L/BAG2/PSEN1/DCUN1D3/CDC20/MASTL/PIN1/DCUN1D4/TOPORS/BAG5	25
BP	GO:2000649	regulation of sodium ion transmembrane transporter activity	25/7096	52/18670	0.08888	0.2526	0.1883	KLHL24/CHP1/NETO2/ACTN4/YWHAH/SLC9A1/FXYD5/TESC/FXYD6/SCN1B/DMD/FXYD1/DNM2/NEDD4/ATP1B1/RANGRF/SCN2B/CAMK2D/CAV3/FXYD7/FXYD2/KIF5B/FXYD3/ATP1A2/WNK2	25
BP	GO:0000724	double-strand break repair via homologous recombination	59/7096	134/18670	0.08897	0.2527	0.1884	USP51/ZFYVE26/MAD2L2/RAD51AP1/MCM6/MCM2/HUS1B/NABP1/UBE2N/KLHL15/ERCC4/MAGEF1/ACTR2/PPP4C/PPP4R2/REC8/SMC5/RNF138/RPA1/RMI2/RAD51B/CCDC155/PALB2/NSMCE2/SAMHD1/SMCHD1/SFPQ/AP5S1/ATM/RAD52/XRCC1/FUS/RFWD3/YY1/RMI1/RAD54B/SWI5/GEN1/TIMELESS/RECQL/KDM4D/POLL/BRCA1/GINS4/MCM5/RTEL1/SWSAP1/TEX15/LIG3/MCM8/ZSWIM7/AUNIP/WAS/TONSL/NUCKS1/SPIDR/FEN1/RECQL4/FIGNL1	59
BP	GO:0033692	cellular polysaccharide biosynthetic process	33/7096	71/18670	0.0894	0.2535	0.189	IGF1/EXTL2/NDST2/HS2ST1/B3GNT8/PER2/EXT2/EXT1/GSK3B/AGL/DYRK2/B3GNT2/PPP1R3E/INSR/GYS1/PPP1R3D/GYG2/CSGALNACT1/B3GNT5/IRS2/PHKG1/PGM2/INPP5K/PPP1R3B/NDST1/PPP1R3F/CSGALNACT2/B4GALT5/PPP1CA/B3GNT4/PPP1CB/ESRRB/MTOR	33
BP	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	33/7096	71/18670	0.0894	0.2535	0.189	IGF1/FYN/SOCS3/LYN/PARP9/STAT3/CD40/JAK2/IL15/TNF/HCLS1/LEP/FLT3/PTK6/CCL5/TNFRSF18/IL6ST/IL6/HDAC2/CLCF1/OSM/HES1/CNTF/IL18/IL3/TSLP/IFNG/TNFSF18/IL12B/CSF1R/ARL2BP/GHR/IL23A	33
BP	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	22/7096	45/18670	0.08943	0.2535	0.189	CDKN1A/MIF/CD44/SHISA5/CD74/NUPR1/DYRK2/HNRNPK/USP28/TMEM109/PML/SIRT1/ELL3/MUC1/AEN/BCL2/DDIT4/HIPK1/TAF9B/TOPORS/TRIAP1/ATAD5	22
BP	GO:0045581	negative regulation of T cell differentiation	22/7096	45/18670	0.08943	0.2535	0.189	ANXA1/IRF1/PTPN2/BCL6/SMAD7/FGL2/IL4R/CBFB/CD74/SOCS5/ZBTB7B/DTX1/NFKBID/HMGB1/CTLA4/NRARP/BMP4/LAG3/HLX/TNFSF4/SOCS1/TBX21	22
BP	GO:1900271	regulation of long-term synaptic potentiation	22/7096	45/18670	0.08943	0.2535	0.189	NRGN/CX3CR1/LILRB2/LGMN/SQSTM1/EPHB2/APOE/GSK3B/STAU1/ABL1/AGER/CREB1/TYROBP/NPTN/ARC/CRTC1/ADCY1/EIF2AK4/RELN/APP/CYP46A1/SHANK3	22
BP	GO:0048145	regulation of fibroblast proliferation	38/7096	83/18670	0.08958	0.2536	0.189	IGF1/FN1/TRIM32/CDKN1A/SKI/WNT5A/MIF/RNASEH2B/MYC/GSTP1/CD74/S100A6/NUPR1/CDK4/TGFB1/PDGFC/EMD/DHX9/PML/CREB1/PDGFB/SPHK1/BAX/CD300A/PDGFA/LIG4/ZMPSTE24/FBXO4/MED25/EGFR/ANXA2P2/WNT1/FOSL2/CCNA2/ANXA2/CDC73/NLRC3/PDGFD	38
BP	GO:0098659	inorganic cation import across plasma membrane	38/7096	83/18670	0.08958	0.2536	0.189	SLC8A1/KCNJ5/KCNJ15/FYN/ATP2B4/SLC9A9/ATP1A1/HFE/SLC9A1/ISCU/SLC39A10/ATP4A/SLC12A9/KCNJ1/SLC39A8/TRPM4/TRPM2/ATP1B2/SLC9A7/ATP1B3/SLC12A2/HCN4/SLC12A8/ATP1B1/KCNJ8/SLC39A12/IFNG/FXYD2/SLC12A1/SLC12A7/SLC12A4/KCNE2/ATP1A2/SLC8A3/FAM155A/SLC9C2/ATP12A/SLC12A6	38
BP	GO:0099587	inorganic ion import across plasma membrane	38/7096	83/18670	0.08958	0.2536	0.189	SLC8A1/KCNJ5/KCNJ15/FYN/ATP2B4/SLC9A9/ATP1A1/HFE/SLC9A1/ISCU/SLC39A10/ATP4A/SLC12A9/KCNJ1/SLC39A8/TRPM4/TRPM2/ATP1B2/SLC9A7/ATP1B3/SLC12A2/HCN4/SLC12A8/ATP1B1/KCNJ8/SLC39A12/IFNG/FXYD2/SLC12A1/SLC12A7/SLC12A4/KCNE2/ATP1A2/SLC8A3/FAM155A/SLC9C2/ATP12A/SLC12A6	38
BP	GO:0033135	regulation of peptidyl-serine phosphorylation	61/7096	139/18670	0.09005	0.2548	0.19	ATP2B4/PINK1/MAD2L2/WNT5A/SH2D3C/PTGS2/SMAD7/MIF/CD44/TNF/ERCC6/HCLS1/TGFB1/HGF/ARRB1/PAK1/LATS1/NSD1/NCK1/VEGFA/PAQR3/ARAF/DMD/RAF1/PPM1F/CREBL2/IL6/SMYD3/TNKS1BP1/BCAR3/FNIP1/PLCL1/BCL2/PRKD2/BAX/INPP5K/IFNK/OSM/INPP5F/DDIT4/DMTN/PWP1/EGFR/TXN/SPRY2/PRKAA1/EIF4G1/PLCL2/HRC/IFNG/RET/OPRD1/MAPKAP1/HSP90AB1/TRIM6/APP/SNCA/PDCD10/BAK1/GCG/NTRK2	61
BP	GO:0051897	positive regulation of protein kinase B signaling	76/7096	176/18670	0.09035	0.2555	0.1905	FYN/CX3CR1/RAC2/PINK1/KITLG/ADAM8/TNF/AKR1C3/GAB1/HCLS1/AXL/TGFB1/HGF/LEP/INSR/NRG1/RHOG/ARFGEF1/ITSN1/IGF1R/P2RY12/MFHAS1/RAC1/CHI3L1/IRS2/LCK/PDGFB/FGF1/PTK2/HPSE/TRAT1/PIK3CD/OSM/TSPYL5/GRB2/PDGFA/ICOS/SEMA5A/C1QBP/VAV1/EGFR/KLB/TXN/IL18/SPRY2/KL/CPNE1/TCF7L2/RET/GCNT2/HBEGF/MAZ/HSP90AB1/PIK3CG/F3/MTDH/GPX1/CD80/MTOR/MEIS3/RTN4/CX3CL1/ITGB1BP1/IAPP/ENG/CCL19/MET/CCR7/FGF23/IL26/ERBB3/RASD2/THPO/FGF6/PIK3CB/PTPRJ	76
BP	GO:0048015	phosphatidylinositol-mediated signaling	78/7096	181/18670	0.09085	0.2568	0.1915	KLF4/IGF1/HTR2B/FYN/EZR/PTPN6/LYN/FLT1/PPARD/PLEKHA1/PRR5/JAK2/TNF/GAB1/PTPN13/HCLS1/UBE3A/EXOC1/IER3/HGF/PTAFR/LEP/INSR/PIK3IP1/NCF1/FLT3/PDGFC/EPOR/FGR/IGF1R/CAT/CCL5/PLCG2/RASGRP1/PIK3R6/SEMA4D/SIRT1/PPP1R16B/IRS2/PDGFB/PPP2R5C/PTK2/CEP55/NYAP1/NEDD4/PIK3CD/OSM/GPR143/INPP5F/UNC5B/PDGFA/BTN2A2/F2R/SERPINA12/PLCB1/C1QBP/EGFR/IL18/MAPK1/STAMBP/FBXL2/OGT/MAZ/FSHR/PPP2R5B/PIK3CG/RELN/CSF1R/PIP5K1B/LIME1/RHOA/TYRO3/NLRC3/ERBB3/PDGFD/NTRK2/PIK3CB/PI4KB	78
BP	GO:0099177	regulation of trans-synaptic signaling	180/7096	437/18670	0.09106	0.2573	0.1918	NRGN/CCR2/FYN/CX3CR1/APBA1/LILRB2/PRKAR2B/SIPA1L1/PINK1/RETN/RAP1B/SYT11/STAT3/PTGS2/RAB11A/PACSIN2/ABHD6/FLOT1/YWHAH/LGMN/SQSTM1/JAK2/KCNC4/TNF/SLC7A11/EPHB2/KRAS/APOE/GSK3B/TSHZ3/MIR142/LRP8/PPP3CB/STXBP1/UNC13B/RAPGEF2/PTK2B/PNKD/ROR2/SRF/STAU1/BAIAP2/SCTR/FBXL20/TPRG1L/ABR/USP46/CDK5/PLK2/HRAS/ABL1/OPHN1/RAB3GAP1/IL1B/DTNBP1/S100B/AGER/RAP1A/CREB1/RAB8A/TYROBP/NPTN/NISCH/HOMER1/EIF4EBP2/PREPL/EGR2/LRRK2/DCC/CYFIP1/ARC/CRTC1/ADCY1/BCR/ARF1/TOR1A/SH3GL1/DNM1/P2RX1/DISC1/ADORA2B/PLCL1/VPS18/NAPA/GNAI2/RGS14/SHISA9/CNTN4/NTNG2/SORCS2/PRKACA/RAB5A/ADRB2/SYNGAP1/MTMR2/SHANK1/CPEB3/CNR2/CAMK2A/NPAS4/CHRM2/F2R/GRIN2C/DNM1L/RASGRF1/CHRNA4/NSMF/PLCB1/FABP5/EGFR/ATP2A2/IQSEC2/DVL1/SLC8A2/MAP1A/KAT2A/LAMA2/PSEN1/FMR1/RAB3A/MAPK1/CBLN1/CHRNB2/P2RY4/PPFIA3/SYT9/PLA2G6/EIF4E/EPHB1/PLCL2/PXK/CDC20/SYT1/KIF5B/RAB3B/RIN1/CACNB3/YWHAG/PSMC5/VAMP1/EIF2AK4/NR2E1/SYT4/PRKCZ/SNCAIP/RELN/MTOR/PICK1/BRSK1/APP/SNCA/KCNMB4/CX3CL1/RNF216/SLC24A2/SSH1/RIMS2/ATP1A2/WNT7A/SLC8A3/SHISA8/CYP46A1/NLGN2/ATAD1/CLSTN3/LZTS1/SYN3/SHANK3/RAB26/P2RY1/TACR2/NTSR1/GHRL/ZMYND8/NTRK2/MEF2C/KISS1/CAMK2B/SYNPO/NPTXR	180
BP	GO:1903844	regulation of cellular response to transforming growth factor beta stimulus	54/7096	122/18670	0.09184	0.2588	0.193	SKIL/SKI/FAM89B/SMAD7/RNF111/SMAD2/NREP/PBLD/LDLRAD4/ZBTB7A/TGFB1/ZNF451/HSPA5/CDKN2B/PMEPA1/CDKN1C/SDCBP/CHST11/SIRT1/CITED2/FLCN/BCL9L/PEG10/SNX6/STRAP/DNM2/ZNF703/MTMR4/LRG1/EID2/HTRA1/UBC/RASL11B/ITGA3/STUB1/ADAM17/CAV3/WFIKKN1/TRIM33/WNT1/LTBP4/ITGA8/TGFB3/TGFB1I1/PIN1/SPINT3/LEMD3/HSP90AB1/MEN1/GLG1/ENG/HTRA4/VEPH1/CD109	54
BP	GO:0006826	iron ion transport	30/7096	64/18670	0.09198	0.2588	0.193	ATP6V0D2/SLC40A1/SLC11A1/MCOLN1/ATP6AP1/SLC25A37/STEAP4/ATP6V1C1/HFE/ATP6V0C/SLC25A28/FTL/ISCU/STEAP3/TCIRG1/ATP6V1A/ATP6V1G3/ATP6V1B2/ATP6V1D/DNM2/ATP6V0E2/SFXN1/IREB2/ATP6V1G2/TFRC/HAMP/LMTK2/IFNG/ATP7A/ATP6V1B1	30
BP	GO:0032768	regulation of monooxygenase activity	30/7096	64/18670	0.09198	0.2588	0.193	HTR2B/VDR/ATP2B4/GCH1/POR/SCARB1/TNF/DDAH2/NFKB1/KRAS/APOE/HIF1A/PTK2B/LEP/IL1B/GLA/SPR/FCER2/DNM2/CNR2/DHFR/EGFR/CAV3/NUS1/CYP27B1/IFNG/TERT/CDH3/SNCA/ZDHHC21	30
BP	GO:0035794	positive regulation of mitochondrial membrane permeability	30/7096	64/18670	0.09198	0.2588	0.193	BMF/SLC35F6/BLOC1S2/PMAIP1/YWHAH/SLC9A1/TMEM14A/GSK3B/MPV17L/FZD9/SFN/CASP8/RHOT2/CHCHD10/SLC25A5/BCL2L11/MAPK8/TMEM102/BCL2/BAX/GZMB/YWHAQ/MUL1/ACAA2/YWHAE/BAD/PPP1R13B/MOAP1/YWHAG/BAK1	30
BP	GO:0046834	lipid phosphorylation	30/7096	64/18670	0.09198	0.2588	0.193	SOCS3/DGKA/IMPAD1/CISH/INPP1/PIK3R3/DGKD/IP6K1/SOCS5/TTC7A/SOCS6/FAM126A/PIK3R6/SOCS7/SPHK1/IMPA2/PIK3CD/PI4K2A/AGK/SOCS1/DGKG/CERK/PIK3CG/SLA2/PIP5K1B/SOCS2/EFR3A/PIK3CB/IMPA1/PI4KB	30
BP	GO:0060135	maternal process involved in female pregnancy	30/7096	64/18670	0.09198	0.2588	0.193	JUNB/VDR/AKR1B1/PTGS2/SPP1/PPARD/RGS2/DAZAP1/EPOR/STOX2/CTSB/UBE2A/ADCY7/PAM/RXRA/ASH1L/APOL2/PPAT/CTSV/LGALS9/ITGA3/MAPK1/CYP27B1/PLA2G6/HAVCR2/MEN1/MTOR/GJA1/GHRL/BMPR2	30
BP	GO:0002320	lymphoid progenitor cell differentiation	11/7096	20/18670	0.09233	0.2588	0.193	SPI1/BATF/ZBTB1/FLT3/FLCN/FNIP1/BCL2/BMP4/LIG4/HES1/SOX4	11
BP	GO:0003323	type B pancreatic cell development	11/7096	20/18670	0.09233	0.2588	0.193	DLL1/WNT5A/GSK3B/RFX3/BMP5/BMP4/CLOCK/BAD/ARNTL/SIDT2/SMO	11
BP	GO:0006677	glycosylceramide metabolic process	11/7096	20/18670	0.09233	0.2588	0.193	PSAP/GALC/PRKCD/CLN3/GLA/ALDH5A1/NAGA/UGCG/PRKAA1/ST6GALNAC3/ST6GALNAC6	11
BP	GO:0010560	positive regulation of glycoprotein biosynthetic process	11/7096	20/18670	0.09233	0.2588	0.193	IGF1/CHP1/IL15/SOAT1/ARFGEF1/POMT1/PLCB1/POMT2/TCF7L2/CCL19/CCR7	11
BP	GO:0010592	positive regulation of lamellipodium assembly	11/7096	20/18670	0.09233	0.2588	0.193	RAC2/TWF2/RAC1/DNM2/HDAC4/FSCN1/WNT1/ATP7A/ARPC2/MTOR/NCKAP1	11
BP	GO:0032793	positive regulation of CREB transcription factor activity	11/7096	20/18670	0.09233	0.2588	0.193	CAMK1D/LRP8/LPAR5/VEGFA/CRTC2/CRTC1/ADCY1/CRTC3/PRKD2/OPRD1/RELN	11
BP	GO:0033194	response to hydroperoxide	11/7096	20/18670	0.09233	0.2588	0.193	JAK2/CD36/PRKCD/AIF1/GPX3/DAPK1/MGST1/XRCC1/GPX1/CHUK/OXR1	11
BP	GO:0035458	cellular response to interferon-beta	11/7096	20/18670	0.09233	0.2588	0.193	IRF1/MNDA/CAPN2/STAT1/AIM2/UBE2K/HTRA2/UBE2G2/TLR3/TRIM6/PNPT1	11
BP	GO:0043371	negative regulation of CD4-positive, alpha-beta T cell differentiation	11/7096	20/18670	0.09233	0.2588	0.193	ANXA1/BCL6/SMAD7/IL4R/CBFB/SOCS5/ZBTB7B/HMGB1/HLX/TNFSF4/TBX21	11
BP	GO:0048670	regulation of collateral sprouting	11/7096	20/18670	0.09233	0.2588	0.193	SPP1/ULK2/IFRD1/SEMA4D/LRP1/DCC/LPAR3/IST1/FSTL4/CRABP2/FGF13	11
BP	GO:1900424	regulation of defense response to bacterium	11/7096	20/18670	0.09233	0.2588	0.193	GRN/ARG2/SYT11/UNC13B/MAPKBP1/SIGLEC16/SIGLEC11/CYBA/HAVCR2/FOXP1/CXCL6	11
BP	GO:1903204	negative regulation of oxidative stress-induced neuron death	11/7096	20/18670	0.09233	0.2588	0.193	ATG7/PINK1/TSC1/SLC7A11/ATF4/HIF1A/NCOA7/FZD1/WNT1/NR4A3/OXR1	11
BP	GO:0006637	acyl-CoA metabolic process	47/7096	105/18670	0.09275	0.2588	0.193	ACOT13/PDK4/CBR4/FAR2/HMGCL/ACOT7/ACSL5/ACSM5/ELOVL5/PDK2/HMGCS1/ACOT9/SCD/OXSM/ACSL4/ACLY/GSTZ1/MCEE/TECR/HSD17B4/MPC2/ACACB/OGDH/ELOVL7/DGAT2/MLYCD/KYNU/ACSL6/THEM4/PDK1/PDHB/FAR1/SUCLG2/DLAT/PDP2/NUDT7/DBI/PDHA2/PDP1/SNCA/ELOVL6/ABCD1/PDPR/TDO2/HSD17B12/ACOT8/PIPOX	47
BP	GO:0035383	thioester metabolic process	47/7096	105/18670	0.09275	0.2588	0.193	ACOT13/PDK4/CBR4/FAR2/HMGCL/ACOT7/ACSL5/ACSM5/ELOVL5/PDK2/HMGCS1/ACOT9/SCD/OXSM/ACSL4/ACLY/GSTZ1/MCEE/TECR/HSD17B4/MPC2/ACACB/OGDH/ELOVL7/DGAT2/MLYCD/KYNU/ACSL6/THEM4/PDK1/PDHB/FAR1/SUCLG2/DLAT/PDP2/NUDT7/DBI/PDHA2/PDP1/SNCA/ELOVL6/ABCD1/PDPR/TDO2/HSD17B12/ACOT8/PIPOX	47
BP	GO:0045185	maintenance of protein location	47/7096	105/18670	0.09275	0.2588	0.193	EZR/SUN2/PINK1/BARD1/FLNA/KEAP1/G3BP2/TMSB10/NFKBIA/PKD2/SUPT7L/VPS13A/TWF2/TLN1/LATS1/GOPC/HSPA5/CDK5/SP100/PML/CLMN/GPAA1/SRI/BBS4/SYNE2/KDELR3/VPS13D/TLN2/GET4/KDELR2/SHANK1/NFKBIE/FLNB/INSIG1/TXN/SCIN/SRGN/SPAG4/CD4/MXI1/TOPORS/DAG1/RER1/ARL2BP/CER1/TONSL/OS9	47
BP	GO:0000422	autophagy of mitochondrion	35/7096	76/18670	0.09281	0.2588	0.193	ATG7/PINK1/ATG3/RNF41/CISD2/FBXW7/ATG14/SQSTM1/CTSK/CSNK2A2/CDC37/FIS1/HIF1A/MAP1LC3A/HTRA2/ATG13/WIPI1/PPARGC1A/MAP1LC3C/ATG9A/VPS13D/MARK2/ATG2B/WDR45B/USP30/SREBF2/FZD5/DNM1L/VDAC1/MUL1/GABARAPL1/CLEC16A/OPTN/ATG12/FUNDC1	35
BP	GO:0050000	chromosome localization	35/7096	76/18670	0.09281	0.2588	0.193	NUP62/RAB11A/SPDL1/ACTR2/CHMP4B/PSRC1/MEI1/SEH1L/CENPE/CCDC155/SPAG5/MIS12/CDC23/CENPC/ATM/CHAMP1/SPICE1/NDC80/MLH1/CHMP2A/NDEL1/NUF2/ZW10/CHMP1A/VPS4B/ACTR3/DLGAP5/KIF2C/KATNB1/KPNB1/CHMP1B/UBE2B/RRS1/KIF14/BOD1	35
BP	GO:0061726	mitochondrion disassembly	35/7096	76/18670	0.09281	0.2588	0.193	ATG7/PINK1/ATG3/RNF41/CISD2/FBXW7/ATG14/SQSTM1/CTSK/CSNK2A2/CDC37/FIS1/HIF1A/MAP1LC3A/HTRA2/ATG13/WIPI1/PPARGC1A/MAP1LC3C/ATG9A/VPS13D/MARK2/ATG2B/WDR45B/USP30/SREBF2/FZD5/DNM1L/VDAC1/MUL1/GABARAPL1/CLEC16A/OPTN/ATG12/FUNDC1	35
BP	GO:0030970	retrograde protein transport, ER to cytosol	15/7096	29/18670	0.09288	0.2588	0.193	BCAP31/TMEM129/EDEM1/SEC61B/UBE2J1/UBE2G2/EDEM2/NPLOC4/DERL1/DERL2/YOD1/HSP90B1/VCP/ERLEC1/OS9	15
BP	GO:0044550	secondary metabolite biosynthetic process	15/7096	29/18670	0.09288	0.2588	0.193	WNT5A/SLC7A11/ZEB2/RAPGEF2/MYO5A/ASIP/BDH2/CYP1A2/MPST/CTH/DCT/CDH3/OCA2/APPL1/CTNS	15
BP	GO:0050855	regulation of B cell receptor signaling pathway	15/7096	29/18670	0.09288	0.2588	0.193	LYN/LPXN/CBFB/CD22/PTPN22/SLC39A10/ELF1/MIR34A/CD300A/GCSAM/NFAM1/PLCL2/FOXP1/PAX5/CMTM3	15
BP	GO:0060142	regulation of syncytium formation by plasma membrane fusion	15/7096	29/18670	0.09288	0.2588	0.193	CAPN2/FLOT1/IL4R/CXCL9/CXCL10/CD53/FLT3LG/EHD1/TYROBP/MYOG/NFATC2/ADAM9/DCSTAMP/TREM2/MYF6	15
BP	GO:0061099	negative regulation of protein tyrosine kinase activity	15/7096	29/18670	0.09288	0.2588	0.193	PTPN2/PTPRC/CBLB/SOCS5/ZFYVE28/ZGPAT/HYAL2/MVP/PTK6/SH3BP5L/SNX6/TSG101/VPS25/PSEN1/FGFR1OP	15
BP	GO:1903513	endoplasmic reticulum to cytosol transport	15/7096	29/18670	0.09288	0.2588	0.193	BCAP31/TMEM129/EDEM1/SEC61B/UBE2J1/UBE2G2/EDEM2/NPLOC4/DERL1/DERL2/YOD1/HSP90B1/VCP/ERLEC1/OS9	15
BP	GO:2000515	negative regulation of CD4-positive, alpha-beta T cell activation	15/7096	29/18670	0.09288	0.2588	0.193	ANXA1/ARG2/BCL6/SMAD7/IL4R/CBFB/SOCS5/ZBTB7B/HMGB1/CD274/LGALS9/HLX/TNFSF4/TBX21/TWSG1	15
BP	GO:2000765	regulation of cytoplasmic translation	15/7096	29/18670	0.09288	0.2588	0.193	DPH3/METTL3/CNBP/NCK1/DPH5/DHX9/DPH2/CPEB1/CPEB3/YBX3/UNK/FMR1/MTOR/DNAJC24/CPEB2	15
BP	GO:0007411	axon guidance	116/7096	276/18670	0.09326	0.2598	0.1937	FYN/VASP/EZR/RAC2/DPYSL2/DOK2/WNT5A/SEMA4B/FEZ2/SIAH1/LAMB2/ALCAM/EPHB2/EXT1/ZSWIM6/GAB1/LYPLA2/CXCL12/PTPRO/PLXNB2/EVL/B3GNT2/MEGF8/RANBP9/MAPK7/PLXNC1/ROBO3/PDLIM7/NCAM1/SCN1B/SEMA4A/VEGFA/CDK5/CYFIP2/TUBB3/OPHN1/NEXN/SEMA4C/SHC1/SEMA4D/LRP1/EFNB1/NPTN/BMP7/RAC1/SPTBN1/EGR2/IRS2/DCC/EPHA8/CYFIP1/MYCBP2/KLF7/DOK1/EPHA10/PTK2/ARX/GRB10/SEMA6B/PLXNA1/GFRA2/NRP1/SEMA3B/PLXND1/GFRA4/L1CAM/NRP2/GFRA3/PIK3CD/CNTN4/NTNG2/DAB1/GRB2/GRB7/UNC5B/SEMA5A/UNC5C/BCL11B/SLIT2/DVL1/LAMA2/SEMA5B/MAPK1/RPL24/POU4F3/EPHB1/PLXNA3/SPTA1/NR4A3/RET/SPTBN2/PLXNA2/ENAH/LGR6/RELN/CSF1R/PRKCQ/APP/DAG1/SHC3/EFNA2/LMX1A/BMPR1B/SMO/BOC/SHANK3/PRKCA/PTCH1/DPYSL5/PTPRM/PIK3CB/EFNA3/LHX9/BMPR2/LAMA1/SLIT3	116
BP	GO:0043525	positive regulation of neuron apoptotic process	27/7096	57/18670	0.09421	0.2622	0.1955	NQO1/ITGAM/GRN/AIFM1/FBXW7/TNF/NUPR1/ATF4/FIS1/MCL1/CDK5/CASP3/CTSZ/SRPK2/TYROBP/ATM/BCL2L11/BAX/HDAC4/CASP2/MAP3K11/PITX3/UBE2M/MAP2K4/PIN1/RHOA/FOXO3	27
BP	GO:0048008	platelet-derived growth factor receptor signaling pathway	27/7096	57/18670	0.09421	0.2622	0.1955	CSRNP1/TXNIP/PTPN2/LRIG2/PLEKHA1/JAK2/CBLB/SGPL1/PDGFC/VEGFA/ABL1/LRP1/PDGFB/BCR/PHF14/NRP1/TIPARP/RGS14/HGS/PDGFA/FER/IFT20/NR4A3/F3/SNCA/PDGFD/PTPRJ	27
BP	GO:0042177	negative regulation of protein catabolic process	58/7096	132/18670	0.09432	0.2624	0.1956	FYN/MAD2L2/CTSA/LRIG2/TIMP2/FLNA/DDRGK1/ATRAID/LAMP3/HFE/IRAK3/FHIT/RYBP/HMGCR/CST3/RELA/CSNK2A2/ALAD/SGTA/NRG1/BANP/OPHN1/FURIN/SDCBP/UBE2J1/PML/UCHL5/UBE2G2/MYCBP2/TIMP4/TIMP1/MGAT3/AZIN1/KLHL40/DERL2/GRIN2C/LAPTM4B/EGFR/YOD1/USP7/ANXA2P2/MAP1A/WNT1/PSEN1/UBXN1/OGT/PIN1/HSP90AB1/CLEC16A/ANXA2/SNCA/BAG5/AZIN2/RGP1/USP19/SMARCC1/ERLEC1/OS9	58
BP	GO:0006024	glycosaminoglycan biosynthetic process	49/7096	110/18670	0.0945	0.2628	0.1959	HS3ST2/VCAN/ABCC5/EXTL2/CHSY1/NDST2/HS2ST1/EXT2/EXT1/NFKB1/HEXA/CHST13/TGFB1/B3GNT2/CHST2/B4GALT6/CSGALNACT1/IL1B/CSPG4/ST3GAL2/XYLT1/CHST11/SLC35D1/B3GALT6/GLCE/CHST5/PDGFB/CHST14/XYLT2/NDST1/CSGALNACT2/HS3ST1/B4GALT5/BCAN/AP2A1/HS3ST3B1/CEMIP/GPC2/B3GNT4/ST3GAL1/CHST12/GCNT2/B3GAT3/HS3ST6/GPC4/SDC3/B4GALT1/SLC35D2/CHST7	49
BP	GO:1903034	regulation of response to wounding	77/7096	179/18670	0.09574	0.2657	0.198	KLF4/SERPINB2/RTN4R/ANXA1/CDKN1A/CLEC7A/GRN/LYN/PROS1/LRIG2/SPP1/PPARD/TFPI/DUSP10/TNFAIP3/MAP2K1/CERS2/SIGLEC10/APOE/HMGCR/CD36/PRKCD/ARFGEF1/TLR4/TNFRSF12A/HRAS/AGER/LRP1/THBD/CRK/SERPING1/PDGFB/PLAUR/MYH9/WFDC1/MIR34A/HPSE/VKORC1/SERPINE1/CDKN1B/SRSF6/TEC/KANK1/NDEL1/SYTL4/INPP5F/PLEK/RTN4RL1/PDGFA/DMTN/F2R/NFE2L2/MYOZ1/CNTF/MYLK/CLASP2/ANXA2P2/INSL3/RAB3A/REG3G/CAPN3/ATP7A/HRG/HBEGF/CD34/F3/ANXA2/MTOR/PRKCQ/ENPP4/TSPAN8/KREMEN1/GJA1/PRKCA/SERPINF2/APCS/CD109	77
BP	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	37/7096	81/18670	0.09586	0.2657	0.198	SKIL/SKI/FAM89B/SMAD7/SMAD2/PBLD/LDLRAD4/ZBTB7A/TGFB1/ZNF451/HSPA5/PMEPA1/CHST11/SIRT1/BCL9L/PEG10/SNX6/STRAP/DNM2/MTMR4/EID2/HTRA1/UBC/RASL11B/STUB1/ADAM17/WFIKKN1/WNT1/TGFB3/TGFB1I1/PIN1/SPINT3/LEMD3/GLG1/HTRA4/VEPH1/CD109	37
BP	GO:0009409	response to cold	24/7096	50/18670	0.09589	0.2657	0.198	FOS/SLC27A1/METRNL/APPL2/TMEM135/THRA/LRP11/PLAC8/NFKBIA/ZNF516/SLC9A1/CXCL10/ADRB1/CASP8/UCP2/PPARGC1A/RBM3/ADRB2/YBX3/ACADVL/UCP1/NFE2L1/PRKAA1/EIF2AK4	24
BP	GO:0046854	phosphatidylinositol phosphorylation	24/7096	50/18670	0.09589	0.2657	0.198	SOCS3/IMPAD1/CISH/INPP1/PIK3R3/IP6K1/SOCS5/TTC7A/SOCS6/FAM126A/PIK3R6/SOCS7/IMPA2/PIK3CD/PI4K2A/SOCS1/PIK3CG/SLA2/PIP5K1B/SOCS2/EFR3A/PIK3CB/IMPA1/PI4KB	24
BP	GO:0033572	transferrin transport	18/7096	36/18670	0.09599	0.2657	0.198	ATP6V0D2/MCOLN1/ATP6AP1/ATP6V1C1/HFE/ATP6V0C/STEAP3/TCIRG1/ATP6V1A/ATP6V1G3/ATP6V1B2/ATP6V1D/DNM2/ATP6V0E2/ATP6V1G2/TFRC/LMTK2/ATP6V1B1	18
BP	GO:0034314	Arp2/3 complex-mediated actin nucleation	18/7096	36/18670	0.09599	0.2657	0.198	IQGAP2/ACTR2/GMFG/ARPC1A/ARPC1B/CYFIP1/CORO1B/ARF1/ARPC5L/JMY/ACTR3B/ACTR3/ARPC4/ARPC2/PICK1/WAS/NCKAP1/FCHSD2	18
BP	GO:0042554	superoxide anion generation	18/7096	36/18670	0.09599	0.2657	0.198	ITGAM/FPR2/ACP5/CLEC7A/SOD1/GNAI3/GSTP1/TGFB1/PRKCD/NCF2/NCF1/TYROBP/NOXA1/AATF/GNAI2/CYBA/CYBB/EGFR	18
BP	GO:0051031	tRNA transport	18/7096	36/18670	0.09599	0.2657	0.198	NUP62/NUP160/NUP214/RAN/NUP85/SEH1L/NUP43/POM121/XPOT/NUP88/NUP107/TOMM20/NUP93/SSB/NUP205/NUP50/POM121C/AAAS	18
BP	GO:0071392	cellular response to estradiol stimulus	18/7096	36/18670	0.09599	0.2657	0.198	CRHBP/AIFM1/SRD5A1/FAM210B/NCOA3/RUVBL2/PPARGC1A/MYOG/BCL2L11/KAT5/ZNF703/ITGA2/HNRNPD/EGFR/DDX18/CCNA2/BCL2L2/NRIP1	18
BP	GO:1901099	negative regulation of signal transduction in absence of ligand	18/7096	36/18670	0.09599	0.2657	0.198	FYN/STRADB/EYA3/TNF/CTNNA1/MAPK7/MCL1/IL1B/IL7/BCL2/IL1A/UNC5B/COL2A1/ZC3HC1/EYA4/MAP2K5/TERT/CX3CL1	18
BP	GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	18/7096	36/18670	0.09599	0.2657	0.198	FYN/STRADB/EYA3/TNF/CTNNA1/MAPK7/MCL1/IL1B/IL7/BCL2/IL1A/UNC5B/COL2A1/ZC3HC1/EYA4/MAP2K5/TERT/CX3CL1	18
BP	GO:0006023	aminoglycan biosynthetic process	51/7096	115/18670	0.09609	0.2658	0.1982	HS3ST2/VCAN/ABCC5/EXTL2/CHSY1/NDST2/HS2ST1/B3GNT8/EXT2/EXT1/NFKB1/HEXA/CHST13/TGFB1/B3GNT2/CHST2/B4GALT6/CSGALNACT1/B3GNT5/IL1B/CSPG4/ST3GAL2/XYLT1/CHST11/SLC35D1/B3GALT6/GLCE/CHST5/PDGFB/CHST14/XYLT2/NDST1/CSGALNACT2/HS3ST1/B4GALT5/BCAN/AP2A1/HS3ST3B1/CEMIP/GPC2/B3GNT4/ST3GAL1/CHST12/GCNT2/B3GAT3/HS3ST6/GPC4/SDC3/B4GALT1/SLC35D2/CHST7	51
BP	GO:0043414	macromolecule methylation	129/7096	309/18670	0.09616	0.2659	0.1982	FOS/TRMT6/SPI1/LMNA/PHF19/MEPCE/FTSJ1/CHTOP/MYC/KDM1B/DPY30/FAM98B/SETDB2/ZNF304/EZH2/PAF1/WDR5B/METTL14/VCPKMT/BTG2/DOT1L/TRMT5/TRMT1/SUV39H2/TET2/SETD4/PRMT9/TYW3/METTL3/MBD1/NDUFAF7/NSD1/PIWIL4/TFB1M/MBD3/BCDIN3D/SETMAR/SETD5/PPM1D/MTRR/LCMT2/TRMT112/FAM98A/PRDM4/SNRPB/TRMT61B/NSUN2/SIRT1/MOV10L1/METTL21A/SETD7/TRMT1L/PAXBP1/SMYD3/METTL22/BCOR/CBLL1/LCMT1/FBL/KMT2E/NTMT1/BTG1/SUV39H1/ASH1L/METTL1/DNMT3L/SETD6/METTL8/HSD17B10/FTSJ3/CTCF/BHMT/FDXACB1/SETDB1/ETF1/DIMT1/CMTR1/ZCCHC4/WDR4/ALKBH8/THUMPD2/PRMT5/COPRS/ZMPSTE24/KDM4D/TRMT11/RNF20/TGS1/PWP1/METTL15/BRCA1/DNMT3A/THUMPD3/PCMTD2/ICMT/MRM1/PRDM2/PRDM6/OGT/RAB3B/RLF/FBLL1/NSUN5P1/MEN1/PCMTD1/CARM1/CMTR2/KMT2B/MTO1/PICK1/RAB3D/PAX7/PAX5/TRMT10C/GTPBP3/GCG/MGMT/EZH1/MTA2/PAXIP1/PRMT1/NSUN6/WDR82/NR1H4/WT1/WDR5/GRHL2/TET1/ZNF335	129
BP	GO:0000096	sulfur amino acid metabolic process	21/7096	43/18670	0.09667	0.2668	0.1989	SMS/GCLM/PCYOX1/ADI1/AHCY/MTR/SLC7A11/NFS1/APIP/MTRR/GCLC/ENOPH1/PCYOX1L/MTAP/TST/MPST/CTH/BHMT/AHCYL2/AHCYL1/MAT1A	21
BP	GO:0034383	low-density lipoprotein particle clearance	21/7096	43/18670	0.09667	0.2668	0.1989	CSK/NPC2/LIPA/SCARB1/SOAT1/HMOX1/CD36/HNRNPK/LDLR/EHD1/DGAT2/AP2A2/AP2S1/AP2A1/ANXA2P2/CES3/NCEH1/AP2M1/ANXA2/NR1H4/CNPY2	21
BP	GO:0038202	TORC1 signaling	21/7096	43/18670	0.09667	0.2668	0.1989	C9orf72/SEH1L/KLHL22/RRAGD/NPRL3/KPTN/MLST8/FLCN/ATM/FNIP1/RRAGA/LAMTOR5/DYRK3/ITFG2/SESN1/TELO2/SMCR8/CLEC16A/MTOR/DEPDC5/SESN2	21
BP	GO:1990573	potassium ion import across plasma membrane	21/7096	43/18670	0.09667	0.2668	0.1989	KCNJ5/KCNJ15/ATP1A1/ATP4A/SLC12A9/KCNJ1/ATP1B2/ATP1B3/SLC12A2/HCN4/SLC12A8/ATP1B1/KCNJ8/FXYD2/SLC12A1/SLC12A7/SLC12A4/KCNE2/ATP1A2/ATP12A/SLC12A6	21
BP	GO:0060191	regulation of lipase activity	44/7096	98/18670	0.09683	0.2672	0.1992	HTR2B/S1PR4/ANXA1/POR/FLT1/RHOC/GNA15/RGS2/APOC1/PLAA/PTAFR/GNAQ/LPAR2/ARF4/NR1H2/P2RY6/HRAS/ABL1/FURIN/CCL5/LMF1/P2RY12/LRP1/ITK/APOA5/BICD1/ARHGAP6/NMUR2/NR1H3/PCSK5/ARL1/LPAR1/EGFR/ABL2/PCSK6/GNA13/APOA1/TXK/PRKCZ/RHOA/SNCA/ADCYAP1R1/RASGRP4/NTRK2	44
BP	GO:0010876	lipid localization	165/7096	400/18670	0.09749	0.2689	0.2005	SLC27A1/KCNN4/HEXB/ANXA1/PLA2G12A/SLC27A3/FABP4/AQP9/STARD4/ATP8B2/RETN/SLCO3A1/ATP8A1/PTPN2/GM2A/NPC2/SPP1/PPARD/MIF/ESYT2/PITPNA/FBXW7/OSBPL9/SLC25A20/PLIN2/APOC1/SCARB1/SQLE/APOL6/PSAP/P2RX7/SOAT1/TNF/NFKBIA/SPNS1/SCP2/CETP/NFKB1/APOE/PRELID1/ALKBH7/LIMA1/SLCO2B1/HDLBP/CPT2/CLN8/OSBPL1A/STARD10/FFAR2/ABCD3/CD36/APOO/LEP/NR1H2/PITPNM1/PRKCD/HNRNPK/ATP11B/ACSL4/LRP10/AKR1C1/ATP10A/ABCA1/IL1B/LAMTOR1/LDLR/C2CD2L/SLC27A2/ACACB/LRP1/EHD1/ATP8B1/TNFRSF11A/STARD7/APOBR/CLU/SIRT1/PDZD8/DGAT2/FABP3/IL6/ABCA5/IRS2/ARV1/APOL1/APOA5/PNPLA8/CFHR4/MIR34A/NME4/MFSD2A/PLA2G3/PLEKHA8/PRKAG2/NCOR1/APOL3/FTO/NMUR2/LCAT/RXRA/VPS51/ABCG1/NR1H3/APOL2/B4GALNT1/INHBA/CPT1A/OSBPL2/ABCB4/SLC10A1/SPNS3/KDM5B/ABCB11/SREBF2/UGCG/VPS4B/TEX2/MEST/GOT2/CPTP/CHKA/ABCA7/PPARA/NMB/ABCA11P/NUS1/FZD4/ANXA2P2/SLC5A8/PRELID2/GALR1/PLEKHA3/STX12/APOA1/PLA2G6/ABCA6/TMEM30A/REN/LBP/ABCC3/ABCC4/CROT/APOL4/SERAC1/ANXA2/TRIAP1/STARD6/SLCO1C1/APOL5/ABCD1/SIGMAR1/VSTM2A/SPX/NRIP1/THRSP/NR1H4/GLTP/RBP4/PTCH1/PLEKHA8P1/ATP10B/NTSR1/GHRL/SLCO1B1/STRA6	165
BP	GO:0001890	placenta development	66/7096	152/18670	0.09803	0.2703	0.2015	JUNB/EPAS1/VDR/SOCS3/RBPJ/SOD1/PTGS2/SPP1/PPARD/ALKBH1/MAP2K1/BIRC2/ADAM19/CEBPB/PKD2/MAP3K4/DAZAP1/BPTF/HIF1A/VASH1/LEP/TFEB/EPOR/CEBPA/ASCL2/CASP8/STOX2/CDKN1C/CTSB/HEY1/BMP7/PDGFB/PCDH12/DNAJB6/PTK2/BMP5/RXRA/ASH1L/CDKN1B/DLX3/SPINT1/HTRA1/GRB2/CTSV/KRT8/FZD5/HES1/ADA/ARNT/PLCD1/EGFR/HEY2/MAPK1/CYP27B1/ZNF568/SNAI1/FOSL1/HSP90AB1/MEN1/GJA1/GRHL2/E2F8/GHRL/CCNF/NRK/BMPR2	66
BP	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	39/7096	86/18670	0.0986	0.2716	0.2025	KLC1/SEC22B/KIF3B/KIFAP3/ARF4/CENPE/BICD2/COPE/ARF5/ERGIC1/DNAJC28/ARFGAP3/TMED10/KIF4A/RAB33B/KIF2A/TAPBP/KDELR3/GOLPH3L/NAPA/COPG2/COG4/COPA/KDELR2/ZW10/STX18/ARCN1/KIF2C/COPZ2/SCFD1/COG7/KLC2/KIF1C/PICK1/RER1/ERGIC2/NBAS/ARF3/ARFGAP1	39
BP	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	39/7096	86/18670	0.0986	0.2716	0.2025	S100A9/S100A8/AIFM1/NLRP3/TNFRSF10A/PMAIP1/NLRP12/JAK2/FAS/TNF/IFT57/TNFSF10/CASP8/PML/CASP5/TRADD/LCK/EGLN3/P2RX1/BAX/CRADD/CASP1/KHDC1/ST20/F2R/TNFRSF10B/MUL1/FADD/TRAF2/CASP4/COL4A3/BAD/DAP/NLRP1/DIABLO/F3/VCP/SNCA/BAK1	39
BP	GO:0044264	cellular polysaccharide metabolic process	46/7096	103/18670	0.09878	0.272	0.2028	IGF1/EXTL2/MANBA/NDST2/HS2ST1/MGAM/B3GNT8/PER2/EXT2/EXT1/GSK3B/AGL/DYRK2/B3GNT2/PPP1R3E/INSR/GYS1/PPP1R3D/GYG2/CSGALNACT1/B3GNT5/PPP1R2/PHKB/IL6ST/IRS2/PCDH12/PHKG1/PGM2/PRKAG2/KHK/INPP5K/PPP1R3B/NDST1/PPP1R3F/CSGALNACT2/B4GALT5/PPP1CC/PPP1CA/B3GNT4/GAA/PYGM/PPP1CB/PYGL/ESRRB/MTOR/G6PC	46
BP	GO:1902686	mitochondrial outer membrane permeabilization involved in programmed cell death	29/7096	62/18670	0.09889	0.2722	0.2029	BMF/SLC35F6/BLOC1S2/PMAIP1/YWHAH/TMEM14A/GSK3B/MPV17L/FZD9/SFN/CASP8/RHOT2/CHCHD10/SLC25A5/BCL2L11/MAPK8/TMEM102/BCL2/BAX/GZMB/YWHAQ/MUL1/ACAA2/YWHAE/BAD/PPP1R13B/MOAP1/YWHAG/BAK1	29
BP	GO:1900006	positive regulation of dendrite development	34/7096	74/18670	0.09947	0.2731	0.2036	ALK/EZH2/APOE/ACTR2/LRP8/SS18L2/BAIAP2/ITSN1/PAFAH1B1/ANKRD27/BMP7/TMEM106B/CAPRIN1/KALRN/CYFIP1/CRTC1/ARF1/BMP5/SHANK1/CPEB3/LPAR1/BHLHB9/DNM1L/SS18L1/PSEN1/FMR1/IL1RAPL1/RELN/MTOR/C21orf91/PARP6/SHANK3/ZMYND8/CAMK2B	34
BP	GO:0006743	ubiquinone metabolic process	10/7096	18/18670	0.09969	0.2731	0.2036	HMGCR/COQ7/COQ5/PDSS1/COQ3/COQ10B/COQ9/COQ6/COQ10A/COQ4	10
BP	GO:0021756	striatum development	10/7096	18/18670	0.09969	0.2731	0.2036	SLC7A11/SECISBP2/ZSWIM6/BBS2/MKKS/LRRK2/BBS4/INHBA/BCL11B/SHANK3	10
BP	GO:0043011	myeloid dendritic cell differentiation	10/7096	18/18670	0.09969	0.2731	0.2036	SPI1/RBPJ/BATF3/BATF/TGFB1/TRAF6/RELB/BATF2/PSEN1/DCSTAMP	10
BP	GO:0045683	negative regulation of epidermis development	10/7096	18/18670	0.09969	0.2731	0.2036	DLL1/EZH2/SRSF6/HES1/CDSN/REG3G/CDH3/SMO/HOXA7/GRHL2	10
BP	GO:0051782	negative regulation of cell division	10/7096	18/18670	0.09969	0.2731	0.2036	TXNIP/MYC/INTU/ASPM/ORC6/C10orf99/ZFYVE19/PTCH1/E2F8/SUSD2	10
BP	GO:0071318	cellular response to ATP	10/7096	18/18670	0.09969	0.2731	0.2036	SOD1/PTGS2/P2RX7/P2RY12/TRPM4/HSP90B1/P2RY4/CIB2/SSH1/P2RY1	10
BP	GO:0071605	monocyte chemotactic protein-1 production	10/7096	18/18670	0.09969	0.2731	0.2036	CLEC7A/GSTP1/SOCS5/IL1B/AGER/LGALS9/MCOLN2/TRPV4/NR1H4/C1QTNF3	10
BP	GO:0071637	regulation of monocyte chemotactic protein-1 production	10/7096	18/18670	0.09969	0.2731	0.2036	CLEC7A/GSTP1/SOCS5/IL1B/AGER/LGALS9/MCOLN2/TRPV4/NR1H4/C1QTNF3	10
BP	GO:0150078	positive regulation of neuroinflammatory response	10/7096	18/18670	0.09969	0.2731	0.2036	CTSC/TNF/NUPR1/MIR142/IL1B/TTBK1/IL6/LRRK2/IL18/TREM2	10
BP	GO:2000319	regulation of T-helper 17 cell differentiation	10/7096	18/18670	0.09969	0.2731	0.2036	NFKBIZ/NLRP3/SMAD7/ZBTB7B/NFKBID/IL12RB1/IL12B/TBX21/MALT1/IL23A	10
BP	GO:1904659	glucose transmembrane transport	48/7096	108/18670	0.1005	0.2751	0.2051	IGF1/PEA15/APPL2/SLC5A3/MEF2A/TSC1/PPARD/PPBP/SLC2A3/SLC2A6/TNF/C2CD5/SLC2A9/SLC2A8/LEP/INSR/IL1B/RAP1A/CREBL2/IRS2/RTN2/ITLN1/CLTCL1/GRB10/PRKAG2/INPP5K/RHOQ/FFAR4/RNASEL/SLC5A4/NFE2L2/FABP5/ASPSCR1/ADIPOR2/PID1/SLC2A10/HNF1A/NR4A3/TERT/STXBP3/SLC5A10/CLIP3/SLC5A9/APPL1/SLC5A2/KLF15/STXBP4/SESN2	48
BP	GO:0000272	polysaccharide catabolic process	14/7096	27/18670	0.1007	0.2751	0.2051	MANBA/MGAM/AGL/PPP1R3D/PHKB/PHKG1/PGM2/PPP1R3B/PPP1CA/GAA/PYGM/PPP1CB/PYGL/G6PC	14
BP	GO:0034067	protein localization to Golgi apparatus	14/7096	27/18670	0.1007	0.2751	0.2051	SYS1/GBP5/VPS13A/CSNK1D/BICD2/PAQR3/RAB33B/VPS13D/ARL1/ARFRP1/IFT20/LACRT/COG7/OPTN	14
BP	GO:0035883	enteroendocrine cell differentiation	14/7096	27/18670	0.1007	0.2751	0.2051	DLL1/WNT5A/GSK3B/RFX3/BMP5/BMP4/PDX1/HES1/CLOCK/BAD/ARNTL/MEN1/SIDT2/SMO	14
BP	GO:0050820	positive regulation of coagulation	14/7096	27/18670	0.1007	0.2751	0.2051	CD36/TLR4/THBD/HPSE/SERPINE1/PLEK/DMTN/F2R/NFE2L2/PSEN1/HRG/F3/ENPP4/SERPINF2	14
BP	GO:0060143	positive regulation of syncytium formation by plasma membrane fusion	14/7096	27/18670	0.1007	0.2751	0.2051	CAPN2/FLOT1/IL4R/CXCL9/CD53/FLT3LG/EHD1/TYROBP/MYOG/NFATC2/ADAM9/DCSTAMP/TREM2/MYF6	14
BP	GO:1902175	regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	14/7096	27/18670	0.1007	0.2751	0.2051	PINK1/SOD1/FBXW7/HIF1A/HSPB1/MAPK7/MCL1/HTRA2/SIRT1/SFPQ/VNN1/NFE2L2/GPX1/BAG5	14
BP	GO:0043484	regulation of RNA splicing	59/7096	135/18670	0.101	0.2759	0.2057	CELF6/TRA2B/NSRP1/JMJD6/SRSF5/TMBIM6/KHDRBS1/HNRNPH1/DAZAP1/RNPS1/THRAP3/RBM7/ZBTB7A/RBM42/AKAP17A/SRSF10/ZNF326/HNRNPK/MBNL1/YTHDC1/RBM4/RBM4B/AHNAK/HABP4/HNRNPA1/HNRNPA2B1/ZPR1/RBM8A/SRPK2/SFSWAP/SRSF3/MBNL3/RBMXL1/RBM3/SETX/CWC22/FUS/SRSF6/PRDX6/SREK1/SRSF7/SF3B4/SRPK1/PRX/C1QBP/FMR1/BRDT/CELF2/SRSF4/ZC3H10/RBM25/PRPF19/CELF3/HMX2/CLK1/SRRM4/ERN1/SAP18/SON	59
BP	GO:0050804	modulation of chemical synaptic transmission	179/7096	436/18670	0.1013	0.2763	0.206	NRGN/CCR2/FYN/CX3CR1/APBA1/LILRB2/PRKAR2B/SIPA1L1/PINK1/RETN/RAP1B/SYT11/STAT3/PTGS2/RAB11A/PACSIN2/ABHD6/FLOT1/YWHAH/LGMN/SQSTM1/JAK2/KCNC4/TNF/SLC7A11/EPHB2/KRAS/APOE/GSK3B/TSHZ3/MIR142/LRP8/PPP3CB/STXBP1/UNC13B/RAPGEF2/PTK2B/PNKD/ROR2/SRF/STAU1/BAIAP2/SCTR/FBXL20/TPRG1L/ABR/USP46/CDK5/PLK2/HRAS/ABL1/OPHN1/RAB3GAP1/IL1B/DTNBP1/S100B/AGER/RAP1A/CREB1/RAB8A/TYROBP/NPTN/NISCH/HOMER1/EIF4EBP2/PREPL/EGR2/LRRK2/DCC/CYFIP1/ARC/CRTC1/ADCY1/BCR/ARF1/TOR1A/SH3GL1/DNM1/P2RX1/DISC1/ADORA2B/PLCL1/VPS18/NAPA/GNAI2/RGS14/SHISA9/CNTN4/NTNG2/SORCS2/PRKACA/RAB5A/ADRB2/SYNGAP1/MTMR2/SHANK1/CPEB3/CNR2/CAMK2A/NPAS4/CHRM2/F2R/GRIN2C/DNM1L/RASGRF1/CHRNA4/NSMF/PLCB1/EGFR/ATP2A2/IQSEC2/DVL1/SLC8A2/MAP1A/KAT2A/LAMA2/PSEN1/FMR1/RAB3A/MAPK1/CBLN1/CHRNB2/P2RY4/PPFIA3/SYT9/PLA2G6/EIF4E/EPHB1/PLCL2/PXK/CDC20/SYT1/KIF5B/RAB3B/RIN1/CACNB3/YWHAG/PSMC5/VAMP1/EIF2AK4/NR2E1/SYT4/PRKCZ/SNCAIP/RELN/MTOR/PICK1/BRSK1/APP/SNCA/KCNMB4/CX3CL1/RNF216/SLC24A2/SSH1/RIMS2/ATP1A2/WNT7A/SLC8A3/SHISA8/CYP46A1/NLGN2/ATAD1/CLSTN3/LZTS1/SYN3/SHANK3/RAB26/P2RY1/TACR2/NTSR1/GHRL/ZMYND8/NTRK2/MEF2C/KISS1/CAMK2B/SYNPO/NPTXR	179
BP	GO:0006120	mitochondrial electron transport, NADH to ubiquinone	26/7096	55/18670	0.1015	0.2766	0.2062	PINK1/NDUFA8/NDUFC1/ISCU/NDUFB11/NDUFS3/NDUFA3/NDUFA11/NDUFA4/NDUFA1/COQ9/NDUFA10/NDUFB1/NDUFB5/NDUFS1/NDUFB8/DNAJC15/NDUFB6/NDUFB3/NDUFS7/NDUFV2/ND4/SNCA/NDUFB2/NDUFS2/NDUFA7	26
BP	GO:0006383	transcription by RNA polymerase III	26/7096	55/18670	0.1015	0.2766	0.2062	SNAPC3/ZNF345/CEBPA/POLR2L/SNAPC1/SNAPC2/ZNF76/POLR2H/IVNS1ABP/POLR1C/POLR2F/MAF1/BRCA1/TBPL1/GTF3A/POLR3E/POLR2K/GTF3C3/BDP1/TBP/MTOR/POLR3F/POLR3GL/SNAPC4/ICE1/POLR3K	26
BP	GO:0045620	negative regulation of lymphocyte differentiation	26/7096	55/18670	0.1015	0.2766	0.2062	ANXA1/IRF1/PTPN2/BCL6/SMAD7/FGL2/IL4R/CBFB/CD74/SOCS5/ZBTB7B/DTX1/NFKBID/HMGB1/CTLA4/NRARP/BMP4/ID2/LAG3/INHBA/PGLYRP4/HLX/TNFSF4/SOCS1/INHA/TBX21	26
BP	GO:0097485	neuron projection guidance	116/7096	277/18670	0.1017	0.2772	0.2066	FYN/VASP/EZR/RAC2/DPYSL2/DOK2/WNT5A/SEMA4B/FEZ2/SIAH1/LAMB2/ALCAM/EPHB2/EXT1/ZSWIM6/GAB1/LYPLA2/CXCL12/PTPRO/PLXNB2/EVL/B3GNT2/MEGF8/RANBP9/MAPK7/PLXNC1/ROBO3/PDLIM7/NCAM1/SCN1B/SEMA4A/VEGFA/CDK5/CYFIP2/TUBB3/OPHN1/NEXN/SEMA4C/SHC1/SEMA4D/LRP1/EFNB1/NPTN/BMP7/RAC1/SPTBN1/EGR2/IRS2/DCC/EPHA8/CYFIP1/MYCBP2/KLF7/DOK1/EPHA10/PTK2/ARX/GRB10/SEMA6B/PLXNA1/GFRA2/NRP1/SEMA3B/PLXND1/GFRA4/L1CAM/NRP2/GFRA3/PIK3CD/CNTN4/NTNG2/DAB1/GRB2/GRB7/UNC5B/SEMA5A/UNC5C/BCL11B/SLIT2/DVL1/LAMA2/SEMA5B/MAPK1/RPL24/POU4F3/EPHB1/PLXNA3/SPTA1/NR4A3/RET/SPTBN2/PLXNA2/ENAH/LGR6/RELN/CSF1R/PRKCQ/APP/DAG1/SHC3/EFNA2/LMX1A/BMPR1B/SMO/BOC/SHANK3/PRKCA/PTCH1/DPYSL5/PTPRM/PIK3CB/EFNA3/LHX9/BMPR2/LAMA1/SLIT3	116
BP	GO:0043244	regulation of protein complex disassembly	50/7096	113/18670	0.1021	0.2781	0.2073	MAP1S/CIB1/TNF/IRAK3/TMOD3/LIMA1/TWF2/RDX/CFL2/CAPZA2/SWAP70/INSR/CAPG/IGF1R/ARHGEF2/CAPZA1/SH3BP1/SPTBN1/SCAF8/SETX/PHF23/AVIL/CFL1/TRIOBP/ADRB2/ETF1/ADD3/PLEK/SEMA5A/DMTN/ZMPSTE24/CLASP2/LMOD3/EIF5A/SCIN/MAP1A/SMCR8/SCAF4/KATNB1/SPTA1/SPTBN2/CLEC16A/JMJD4/MTRF1/NAV3/TRPV4/TTBK2/SLN/FGF13/UPF1	50
BP	GO:0055072	iron ion homeostasis	36/7096	79/18670	0.1026	0.2793	0.2082	EPAS1/SLC40A1/SLC11A1/SOD1/ATP6AP1/SLC25A37/NCOA4/CUL1/STEAP4/MYC/HFE/HMOX1/SLC25A28/FBXL5/CYBRD1/HIF1A/FTL/ISCU/STEAP3/HYAL2/ABCB6/TTC7A/ATP6V1A/ACO1/BDH2/SRI/GLRX3/CAND1/SLC46A1/IREB2/TFRC/HAMP/EIF2AK1/EPB42/PICALM/ABCB7	36
BP	GO:0008406	gonad development	92/7096	217/18670	0.1027	0.2793	0.2082	WNT5A/SOD1/RETN/SRD5A1/NCOA4/FLNA/PLEKHA1/KITLG/LFNG/RDH10/CEBPB/LRRC6/NUPR1/AKR1C3/UBE3A/REC8/HMGCS1/UTF1/ARRB1/NUDT1/CTNNA1/SGPL1/ZNF830/LEP/ADAM15/INSR/PTX3/EIF2B5/HSPA5/VEGFA/CASP3/TNFSF10/WDR19/HSD17B4/IDH1/SIRT1/BASP1/EIF2S2/MKKS/CCND1/CITED2/ASPM/ATM/PATZ1/IMMP2L/BCL2L11/MGST1/BCL2/TBC1D20/BAX/HMGB2/TIPARP/ERCC1/CASP2/NUP107/INHBA/CTSV/HYAL3/YBX3/MMP14/FZD4/SLIT2/CCDC182/FANCG/TAF4/RHOBTB3/HOXA10/NASP/FSHR/TLR3/INHA/REN/RXFP2/WNT2B/KMT2B/FANCA/ZFP42/IRX5/MEA1/BCL2L2/EIF2B2/TFAP2C/CSDE1/GJA1/NRIP1/BMPR1B/AMHR2/MMP19/WT1/FOXO3/LHX9/SLIT3	92
BP	GO:0060348	bone development	92/7096	217/18670	0.1027	0.2793	0.2082	IGF1/SIGLEC15/PTGER4/PTPN6/ACP5/SKI/NOTCH2/POR/CHSY1/SRD5A1/ATP6AP1/SMAD5/FBXW7/DCHS1/PTPRC/IFT172/AKAP13/IMPAD1/LILRB1/THBS3/LRP5/DHRS3/TGFB1/TULP3/RAB23/MEGF8/LEP/SRF/CSGALNACT1/IFT80/RYR1/PDGFC/BMP2/PAFAH1B1/NAB1/LTBP3/XYLT1/SEMA4D/SFRP4/TIFAB/TYROBP/TAL1/SULF2/SPARC/ANXA6/VKORC1/BBX/BMP4/CYP26B1/PAPSS2/COL7A1/PLS3/MMP14/ZMPSTE24/INSIG1/ANKRD11/COL20A1/COL2A1/ANXA2P2/WNT1/TRIM45/SHOX2/LRRC17/TGFB3/CLDN18/COL6A3/TMEM38B/CARM1/MSX1/GLG1/MEIS1/TTC9/ANXA2/FOXP1/MBTPS2/RHOA/TRPV4/SLC9B2/ENG/MMP16/PPIB/TMEM119/DYM/CER1/GJA1/GREM1/INPPL1/BMPR1B/GHRL/THPO/MEF2C/BMPR2	92
BP	GO:0006111	regulation of gluconeogenesis	23/7096	48/18670	0.1035	0.2808	0.2093	FBP1/PTPN2/SIK1/KAT2B/PDK2/LEP/DDB1/SLC35B4/SIRT1/DGAT2/PPARGC1A/NLN/FOXK2/SERPINA12/MST1/PPARA/KAT2A/OGT/GCG/SESN2/C1QTNF3/WDR5/FAM3A	23
BP	GO:0030865	cortical cytoskeleton organization	23/7096	48/18670	0.1035	0.2808	0.2093	EZR/PLS1/ARF6/FMNL3/FMNL1/TNF/TLN1/EPB41L1/CDK5/PAFAH1B1/WIPF2/RHOQ/PPP2R3C/PLEK/CALR/EPB41/LLGL1/WIPF1/EPB41L2/TRPV4/WAS/ROCK2/NCKAP1	23
BP	GO:0035272	exocrine system development	23/7096	48/18670	0.1035	0.2808	0.2093	WLS/TNF/TGFB1/HGF/INSR/BMP7/EDA/PLXNA1/NRP1/PLXND1/EDAR/TGM2/PDX1/PDGFA/EGFR/TGFB3/TFCP2L1/BTBD7/POLB/DAG1/TWSG1/RAB26/LAMA1	23
BP	GO:0043628	ncRNA 3'-end processing	23/7096	48/18670	0.1035	0.2808	0.2093	INTS5/INTS7/TOE1/ELAC1/USB1/INTS8/RPS21/FBL/EXOSC2/HSD17B10/EXOSC7/INTS2/SSB/ERI3/EXOSC9/EXOSC3/FBLL1/EXOSC6/TRMT10C/EXOSC8/INTS6/POLR3K/EXOSC5	23
BP	GO:0051972	regulation of telomerase activity	23/7096	48/18670	0.1035	0.2808	0.2093	KLF4/MYC/MAP3K4/PKIB/NAF1/HNRNPA2B1/XRCC5/PTGES3/MAPKAPK5/PARM1/PARP3/HNRNPD/CCT4/MAPK1/ACD/HSP90AB1/MEN1/PRKCQ/POT1/GREM1/PNKP/NEK7/GRHL2	23
BP	GO:0060324	face development	23/7096	48/18670	0.1035	0.2808	0.2093	CSRNP1/SKI/WNT5A/PLEKHA1/MAP2K1/RRAS/TGFB1/SGPL1/SRF/CRISPLD2/RAB3GAP1/RAF1/MKKS/BBS4/TIPARP/ANKRD11/MAPK1/TGFB3/MSX1/MMP2/MYH3/GRHL2/STRA6	23
BP	GO:0006409	tRNA export from nucleus	17/7096	34/18670	0.104	0.2813	0.2097	NUP62/NUP160/NUP214/RAN/NUP85/SEH1L/NUP43/POM121/XPOT/NUP88/NUP107/NUP93/SSB/NUP205/NUP50/POM121C/AAAS	17
BP	GO:0010765	positive regulation of sodium ion transport	17/7096	34/18670	0.104	0.2813	0.2097	CHP1/ACTN4/SLC9A1/TESC/SCN1B/DMD/ATP1B2/ATP1B3/ARF1/FXYD1/DNM2/ATP1B1/AHCYL1/PKP2/KIF5B/CNTN1/WNK2	17
BP	GO:0010922	positive regulation of phosphatase activity	17/7096	34/18670	0.104	0.2813	0.2097	PPP1R15A/JAK2/PTPRC/BMP2/SLC39A10/PPP1R15B/ITGA2/CD300A/PLEK/IFNG/CHP2/MTMR9/PPP1R14D/HSP90AB1/CD33/MTOR/MEF2C	17
BP	GO:0032212	positive regulation of telomere maintenance via telomerase	17/7096	34/18670	0.104	0.2813	0.2097	MAP3K4/PKIB/NAF1/HNRNPA1/XRCC5/ATM/MAPKAPK5/CCT4/FBXO4/CCT8/ATR/MAPK1/ACD/PRKCQ/POT1/PNKP/NEK7	17
BP	GO:0032660	regulation of interleukin-17 production	17/7096	34/18670	0.104	0.2813	0.2097	MYD88/NOD2/IL27RA/ARG2/LY9/IL15/TGFB1/TLR4/IL6/SPHK1/OSM/IL18/TNFSF4/IFNG/IL12B/PRKCQ/IL23A	17
BP	GO:0071431	tRNA-containing ribonucleoprotein complex export from nucleus	17/7096	34/18670	0.104	0.2813	0.2097	NUP62/NUP160/NUP214/RAN/NUP85/SEH1L/NUP43/POM121/XPOT/NUP88/NUP107/NUP93/SSB/NUP205/NUP50/POM121C/AAAS	17
BP	GO:0140115	export across plasma membrane	17/7096	34/18670	0.104	0.2813	0.2097	SLC8A1/SLC40A1/ATP1A1/SLC9A1/KCNA3/KCNE3/KCNIP2/ATP4A/ATP1B2/ATP1B3/FXYD1/ATP1B1/KCNQ1/FXYD2/KCNE2/ATP1A2/ATP12A	17
BP	GO:1904030	negative regulation of cyclin-dependent protein kinase activity	17/7096	34/18670	0.104	0.2813	0.2097	CDKN2D/CDKN1A/TNFAIP3/KAT2B/HEXIM1/LATS1/TFAP4/CEBPA/CDKN2B/CASP3/CDKN1C/HEXIM2/CDKN1B/CDKN2C/IPO7/LATS2/MEN1	17
BP	GO:0007520	myoblast fusion	20/7096	41/18670	0.1046	0.2818	0.2101	MYOF/CAPN2/FLOT1/IL4R/CXCL9/CXCL10/CD53/PLEKHO1/DYRK1B/FLT3LG/EHD1/MYH9/PTGFRN/MYOG/ADAM12/NFATC2/CAV3/WNT1/CACNA1H/MYF6	20
BP	GO:0010955	negative regulation of protein processing	20/7096	41/18670	0.1046	0.2818	0.2101	IL1R2/CD55/SIRT4/BIRC2/A2M/CD59/CAST/CTSZ/SERPING1/LRRK2/CR1/CST7/VSIG4/SERPINE1/BIRC3/BIRC7/MDM2/GLG1/XIAP/SERPINF2	20
BP	GO:0042572	retinol metabolic process	20/7096	41/18670	0.1046	0.2818	0.2101	AKR1B1/ALDH1A1/RDH10/RETSAT/AKR1C3/DHRS3/DHRS9/CYP1B1/RDH16/PLB1/DGAT2/RDH12/CYP2D6/CYP1A2/RDH5/AKR1B10/ADH1B/ADH7/RBP4/PNPLA4	20
BP	GO:0045005	DNA-dependent DNA replication maintenance of fidelity	20/7096	41/18670	0.1046	0.2818	0.2101	SLFN11/ALYREF/ZNF830/ETAA1/SETMAR/SAMHD1/DONSON/TIPIN/CDK9/PCNA/BOD1L1/RFWD3/GEN1/TIMELESS/FANCM/RTEL1/POLD1/TONSL/NUCKS1/ZRANB3	20
BP	GO:0045616	regulation of keratinocyte differentiation	20/7096	41/18670	0.1046	0.2818	0.2101	VDR/ZFP36/CBFB/CTSK/TRIM16/NCOA3/KRT36/ALOX15B/SRSF6/CTSV/CDSN/AQP3/CYP27B1/REG3G/KRT84/ROCK2/HOXA7/GRHL2/GRHL1/CD109	20
BP	GO:0050798	activated T cell proliferation	20/7096	41/18670	0.1046	0.2818	0.2101	IGF1/FYN/CLC/CASP3/ABL1/AGER/ICOSLG/HMGB1/IGFBP2/PDCD1LG2/IL12RB1/CD274/LGALS9/BTN2A2/IL18/FADD/BTN3A1/IL12B/CD24/IL23A	20
BP	GO:0098927	vesicle-mediated transport between endosomal compartments	20/7096	41/18670	0.1046	0.2818	0.2101	EZR/WDR91/FAM160A2/MAP2K1/WDR81/RDX/CORO1A/ANKRD27/HOOK2/KIF16B/EMP2/HOOK3/RAB5A/MTMR2/MAP2K2/MAPK1/MSN/LMTK2/STX8/SNX16	20
BP	GO:1903318	negative regulation of protein maturation	20/7096	41/18670	0.1046	0.2818	0.2101	IL1R2/CD55/SIRT4/BIRC2/A2M/CD59/CAST/CTSZ/SERPING1/LRRK2/CR1/CST7/VSIG4/SERPINE1/BIRC3/BIRC7/MDM2/GLG1/XIAP/SERPINF2	20
BP	GO:0071621	granulocyte chemotaxis	54/7096	123/18670	0.1048	0.2824	0.2105	S100A9/S100A8/S100A12/RAC2/ANXA1/BST1/IL17RA/CAMK1D/PPBP/CXCL9/CXCL11/CD74/CXCL10/MPP1/CXCL13/PDE4B/CMKLR1/IL1B/CCL5/CCL7/IL1RN/RAC1/CXCR1/CKLF/C3AR1/MOSPD2/CCL13/CCL8/PIK3CD/C1QBP/VAV1/CXCR2/CCL20/JAM3/PREX1/SLIT2/CCL26/CSF3R/PIK3CG/LBP/TRPV4/C5AR2/DAPK2/CX3CL1/CCL19/TIRAP/CCL4/CCR7/CCL24/IL23A/IL17RC/CXCL6/S100A14/IL37	54
BP	GO:0007519	skeletal muscle tissue development	69/7096	160/18670	0.1049	0.2824	0.2105	HIVEP3/FOS/DLL1/SKI/GPCPD1/FLOT1/KLHL41/VAMP5/EGR1/NUPR1/HMGCR/BTG2/MYL6B/TGFB1/CFL2/RYR1/CDK5/SVIL/EMD/UQCC2/NR1D2/S100B/HOMER1/EGR2/BCL9L/NLN/MYL6/MYOG/BCL2/CYP26B1/HDAC4/KCNAB1/KLF5/YBX3/ZBTB18/KLHL40/HLX/FLNB/MYOZ1/COPS2/LMOD3/BIN3/MYOM2/PRKAA1/SHOX2/DNER/CASQ1/MEGF10/EPHB1/ARNTL/HLF/RB1/ZNF689/GPX1/PITX1/RHOA/TAZ/HMG20B/PAX7/P2RX2/PAX5/USP19/WNT10B/ACTA1/SMO/KEL/TLL2/MEF2C/MYF6	69
BP	GO:0006816	calcium ion transport	178/7096	434/18670	0.105	0.2826	0.2107	SLC8A1/HTR2B/VDR/PKD2L1/FYN/KCNN4/PTPN6/LILRB2/ATP2B4/TMEM37/LYN/MCOLN1/TPCN1/DIAPH1/TMBIM6/PTGS2/LILRA5/SLC25A25/ORAI2/LILRA2/CXCL9/YME1L1/CXCL11/PTPRC/P2RX7/SLC9A1/CXCL10/PKD2/LILRB1/CXCL12/CACNA2D3/TGFB1/KCNE3/ITPR1/WFS1/PTK2B/MYO5A/PANX1/CORO1A/P2RY6/CATSPER1/MCU/AHNAK/RYR1/SARAF/CDK5/PDE4B/ABL1/STIM2/GSTO1/HOMER3/CCL5/PLCG2/PML/CYSLTR1/ATP2C1/P2RY12/DMD/TRPM4/AFG3L2/TRPM2/HOMER1/ORAI3/TMC2/LCK/PDGFB/G6PD/IL16/SPINK1/CCR5/SUMO1/PSEN2/SRI/MIR34A/RASA3/P2RX1/NMUR2/ANXA6/BCL2/GNAI2/CCL8/BAX/INPP5K/ATP1B1/MS4A1/CHRNA10/PRKACA/LPAR3/CYBA/MICU1/MCOLN2/CAMK2A/ZMPSTE24/F2R/GRIN2C/DNM1L/VDAC1/CHRNA4/SLC35G1/MYLK/CAMK2D/PLCB1/CEMIP/ORAI1/CAV3/ATP2A2/ANXA2P2/LETM1/SLC8A2/STAC2/PSEN1/FMR1/GPR35/CHRNB2/PARL/YWHAE/CYP27B1/EPB41/CASQ1/PLA2G6/CD84/SLC24A4/CAPN3/CASQ2/CACNG6/HRC/PKD1L2/MICU3/EFHB/CLCA1/BDKRB1/OPRD1/CD4/EHD3/TMEM38B/LACRT/IL1RAPL1/PIK3CG/PMPCB/CACNB3/REM2/CD33/OPRL1/ANXA2/LIME1/RHOA/TRPV4/SNCA/CX3CL1/P2RX2/SLC24A2/CCL19/SLN/TRPC4AP/BAK1/CHERP/GCG/CCL4/TMC1/KCNE2/ATP1A2/CCR7/SLC8A3/MCOLN3/CACNA2D4/FAM155A/GJA1/CACNA1H/CACNA1F/ADCYAP1R1/TRPV3/BIN1/TRPV2/NTSR1/PACSIN3/MICU2/CAMK2B/P2RX5	178
BP	GO:0048144	fibroblast proliferation	38/7096	84/18670	0.1054	0.2835	0.2114	IGF1/FN1/TRIM32/CDKN1A/SKI/WNT5A/MIF/RNASEH2B/MYC/GSTP1/CD74/S100A6/NUPR1/CDK4/TGFB1/PDGFC/EMD/DHX9/PML/CREB1/PDGFB/SPHK1/BAX/CD300A/PDGFA/LIG4/ZMPSTE24/FBXO4/MED25/EGFR/ANXA2P2/WNT1/FOSL2/CCNA2/ANXA2/CDC73/NLRC3/PDGFD	38
BP	GO:0034330	cell junction organization	121/7096	290/18670	0.1055	0.2837	0.2115	S100A10/FN1/VASP/MPP5/ARF6/TSC1/CSK/ITGA5/RAP1B/PLEKHA7/PLEC/FLNA/SMAD7/FBLIM1/RHOC/LSR/ACTN4/FLOT1/TRIP6/F11R/CBFB/LDB1/VCL/TNF/SLC9A1/PTPRO/DUSP3/PEAK1/ACTB/TLN1/TGFB1/RDX/CTNNA1/RAPGEF2/PTK2B/HEG1/SRF/ACTN1/LAMB3/KIFC3/VEGFA/ABL1/OPHN1/CD151/IQSEC1/NUMB/CAPZA1/STRN/RAP1A/TESK2/LRP1/GPBAR1/PPM1F/SLK/SH3BP1/RAC1/MAPRE2/CDH5/MYO1C/FLCN/PTK2/ARHGAP6/BCR/LIMCH1/NPHP4/HDAC7/NRP1/BCL2/ZNF703/WDPCP/BCAS3/MICALL2/TLN2/PRKACA/PVR/ITGA2/FZD5/PARD6B/HIPK1/MMP14/DMTN/CORO1C/F2R/CLASP2/RAB8B/PKN2/RCC2/CDH17/MPP7/FSCN1/TGFB3/CDH10/SNAI1/GNPAT/NUMBL/PKP2/HRG/MTDH/CSF1R/MAP4K4/PRTN3/CADM3/RHOA/TRPV4/KRT14/CDH3/LIMS1/CDHR3/ITGB1BP1/ROCK2/NLGN2/GJA1/NR1H4/PRKCA/CDH26/GRHL2/MACF1/GRHL1/CLDN6/PTPRJ/FMN1	121
BP	GO:0043270	positive regulation of ion transport	115/7096	275/18670	0.1063	0.2854	0.2128	CCR2/KCNMB1/PINK1/ATP8A1/LILRA5/CHP1/FLNA/MIF/CTSS/ACTN4/LILRA2/CXCL9/CEBPB/CXCL11/P2RX7/EPHB2/SLC9A1/CXCL10/TESC/PKD2/APOE/PRELID1/CXCL12/ATF4/STXBP1/KCNE3/KCNIP2/ARL6IP1/PTAFR/WFS1/LEP/PRKCD/P2RY6/SCN1B/ABL1/STIM2/RAB3GAP1/GSTO1/IL1B/CCL5/PLCG2/P2RY12/TNFRSF11A/DMD/CHCHD10/HOMER1/ATP1B2/FABP3/PDGFB/G6PD/ARC/SUMO1/SRI/ATP1B3/ARF1/P2RX1/LRRC52/FXYD1/DNM2/BAX/ATP1B1/LPAR3/ADRB2/FHL1/KCNQ1/ABCB4/CAMK2A/F2R/ABCA7/MYLK/AHCYL1/CEMIP/ORAI1/AMIGO1/ANXA2P2/STAC2/PSEN1/CHRNB2/APOA1/CASQ1/TREM2/PLA2G6/CAPN3/IFNG/PKP2/KIF5B/BDKRB1/CD4/EHD3/RAB3B/LACRT/SNX4/CACNB3/SYT4/RELN/ANXA2/TRIAP1/SNCA/CX3CL1/P2RX2/BAK1/GCG/CCL4/KCNE2/ADCYAP1R1/SHANK3/TRPV3/P2RY1/HTR3A/CNTN1/TACR2/TRPV2/NTSR1/WNK2/P2RX5	115
BP	GO:0043966	histone H3 acetylation	28/7096	60/18670	0.1064	0.2854	0.2128	SPI1/DR1/LDB1/SUPT7L/KAT2B/TRIM16/SIN3A/ZNF451/JADE3/MBIP/KAT7/TAF5L/TAF12/CRTC2/SIRT1/BRPF1/TAF6L/BRCA1/KAT2A/TAF9B/MCM3AP/ING4/JADE1/POLE4/TADA3/KAT6B/WDR5/NAA60	28
BP	GO:0045927	positive regulation of growth	113/7096	270/18670	0.1065	0.2854	0.2128	IGF1/S100A9/S100A8/FN1/TRIM32/EZR/DLL1/PLS1/RBPJ/PIM1/ADNP2/RAB11A/PPARD/RPS6KA3/CIB1/SLC9A1/PLAA/CXCL12/TWF2/PAK1/WFS1/MEGF8/PTK2B/LEP/SRF/INSR/PARP2/VEGFA/TNFRSF12A/SFN/KLHL22/PAFAH1B1/ZPR1/GDI1/SDCBP/SEMA4D/ACACB/LRP1/CREB1/BBS2/IL7/PPM1F/BASP1/MKKS/CDKN2AIP/EIF4G2/CYFIP1/DNPH1/DDX3X/SERP1/ARX/BBS4/SPHK1/BMPR1A/NRP1/DISC1/BCL2/KDM2B/EXOSC2/L1CAM/GPR21/LPAR3/IST1/NDEL1/CYBA/YBX3/SEMA5A/MMP14/DERL2/HLX/PLCB1/EGFR/MUL1/SLC25A33/ADAM17/HEY2/ITSN2/HAMP/MAPK1/SUPV3L1/TAF9B/EIF4G1/RASAL1/CAPN3/MAP3K13/RUFY3/EXOSC9/FGFR1OP/TFCP2L1/SYT1/CPNE9/PIN1/HBEGF/MAP2K5/SYT2/SYT4/MTOR/HPN/RHOA/GHRH/CRABP2/RIMS2/GHR/PPIB/SMO/WT1/MACF1/PRSS2/TRPV2/GHRL/MEF2C/BMPR2/RFTN1	113
BP	GO:0071466	cellular response to xenobiotic stimulus	77/7096	180/18670	0.1066	0.2854	0.2128	CRHBP/NQO1/EPHX1/SLC8A1/S100A12/ATG7/POR/CMBL/SRD5A1/ACAA1/MGST2/GSTP1/EGR1/AHRR/AKR7A2/TGFB1/CYP1B1/AKR7A3/PCK2/CYB5B/TFAP4/CYP2J2/RYR1/AKR1C1/CYP2S1/STAT5A/GSTO1/AIF1/AHR/CES2/GSTA1/PDGFB/GSTM3/SMYD3/PPARGC1A/PTGES3/ARNT2/BPHL/MGST1/CYP2D6/CYP1A2/CBR3/PCNA/CYP26B1/GSTM5/AS3MT/DDIT4/GSTM4/CYB5R3/ARNT/EGFR/CES3/MGST3/RORA/CASQ2/EIF4E/NAT2/TMEM38B/HSP90AB1/RB1/CCNA2/SULT1B1/CYP26A1/MARC2/FMO2/NAT1/CRYZ/CYP2W1/GHR/CYP2A6/CYP46A1/PHGDH/ALDH3A1/CYP2C8/PTGS1/CYP2U1/AIP	77
BP	GO:0052547	regulation of peptidase activity	185/7096	452/18670	0.1067	0.2854	0.2128	KLF4/S100A9/S100A8/SERPINA1/RARRES1/SERPINB2/FN1/FYN/SERPINB9/CDKN2D/MAPK12/CLEC7A/CST6/GRN/BCL10/LYN/PINK1/POR/AIFM1/GRAMD4/STAT3/PROS1/CTSD/PTGS2/PSMB9/GAPDH/TIMP2/NLRP3/TNFRSF10A/TFPI/SH3RF1/PMAIP1/RPS6KA3/LXN/PSMB8/MBP/DDRGK1/BIRC2/UBE2Z/LGMN/CD44/MYC/NLRP12/PZP/JAK2/LAMP3/FAS/BCAP31/A2M/TNF/PEBP1/IFT57/PRELID1/PSME1/CST3/AIM2/MICAL1/HGF/ARL6IP1/CLPX/FIS1/ARRB1/CAST/SERPINB1/TFAP4/HTRA2/VEGFA/RENBP/SFN/CYFIP2/SERPINB8/TNFSF10/CASP8/PAK2/FURIN/CPAMD8/AGER/ADRM1/DAPK1/PML/CASP5/HMGB1/WFDC12/TRADD/RAF1/PPM1F/SIRT1/UCHL5/SERPING1/TTBK1/LCK/PLAUR/CR1/EGLN3/SPINK1/DNAJB6/TIMP4/PDCD5/SERPINA9/DDX3X/WFDC1/CST7/PRR7/FNIP1/BCL2L11/P2RX1/PSME3/MMP9/MEFV/BAX/SERPINE1/CRADD/COL7A1/TIMP1/BIRC3/SPINT1/CASP1/CSTA/KHDC1/SPOCK2/LGALS9/RFFL/ST20/AMBP/BIRC7/MAP3K5/F2R/LAMTOR5/CAAP1/TNFRSF10B/SERPINI2/SERPINA12/MUL1/FADD/TRAF2/CASP4/WFIKKN1/MDM2/YWHAE/COL4A3/BAD/DAP/SERPINA7/NLRP1/IGBP1/UBXN1/ST18/SPOCK1/HRG/CRIM1/SERPINB4/COL6A3/A2ML1/PCID2/SPINT3/MAP2K5/SPINK6/NLRP2/WDR35/DIABLO/F3/SERPINB6/GPX1/VCP/PI3/RHOA/TRIAP1/APP/SNCA/MALT1/BAK1/SERPINB10/XIAP/MGMT/PICALM/ROCK2/AKIRIN2/SERPINF2/BIN1/ITIH3/SIAH2/MIR205/CD109/EFNA3/SOX7	185
BP	GO:0071559	response to transforming growth factor beta	107/7096	255/18670	0.1071	0.2854	0.2128	FOS/FYN/CX3CR1/SKIL/APPL2/ACVR2B/SKI/ARHGEF18/WNT5A/FAM89B/ITGB5/SMAD5/SMAD7/RNF111/SMAD2/F11R/NREP/PBLD/LDLRAD4/ZBTB7A/TGFB1/ZNF451/HPGD/MAPK7/COL4A2/HYAL2/HSPA5/CDKN2B/USP9X/PMEPA1/LTBP3/FURIN/NLK/CDKN1C/SDCBP/CHST11/PML/CREB1/CRK/SIRT1/ACVR1B/CDH5/PPARGC1A/CITED2/FLCN/BCL9L/PDCD5/PEG10/PTK2/ZYX/WWOX/SNX6/HDAC2/BMPR1A/TAB1/STRAP/DNM2/ZNF703/MTMR4/LRG1/EID2/HTRA1/UBC/RASL11B/ITGA3/STUB1/PXN/ADAM17/CAV3/WFIKKN1/ADAM9/TRIM33/WNT1/LTBP4/ZFP36L2/ITGA8/TGFB3/TGFB1I1/PIN1/GCNT2/SPINT3/LEMD3/HSP90AB1/CILP/MEN1/SOX5/GLG1/PRKCZ/RHOA/LIMS1/ENG/WNT10A/HTRA4/WNT7A/ROCK2/APPL1/STK16/BMPR1B/AMHR2/TWSG1/VEPH1/PDGFD/CD109/MEF2C/FOXH1/BMPR2/GDF5	107
BP	GO:0000076	DNA replication checkpoint	9/7096	16/18670	0.1076	0.2854	0.2128	HUS1B/ZNF830/TIPIN/RAD17/TIMELESS/TICRR/CLSPN/RAD9A/TOPBP1	9
BP	GO:0009208	pyrimidine ribonucleoside triphosphate metabolic process	9/7096	16/18670	0.1076	0.2854	0.2128	AK3/CTPS2/NME3/NME4/NME1/UCK1/CTPS1/CAD/UCKL1	9
BP	GO:0010225	response to UV-C	9/7096	16/18670	0.1076	0.2854	0.2128	MAP3K4/POLH/YY1/ST20/IMPACT/C9orf116/MDM2/DCUN1D3/BAK1	9
BP	GO:0010919	regulation of inositol phosphate biosynthetic process	9/7096	16/18670	0.1076	0.2854	0.2128	PTAFR/PTK2B/P2RY6/PLEK/SNCA/CD244/ADCYAP1R1/P2RY1/NTSR1	9
BP	GO:0019377	glycolipid catabolic process	9/7096	16/18670	0.1076	0.2854	0.2128	FUCA1/HEXB/GM2A/PSAP/GALC/PRKCD/GLA/NAGA/NEU1	9
BP	GO:0022038	corpus callosum development	9/7096	16/18670	0.1076	0.2854	0.2128	RTN4R/EPHB2/ZEB2/CDK5/PAFAH1B1/TSKU/RTN4RL1/LPAR1/RTN4RL2	9
BP	GO:0030033	microvillus assembly	9/7096	16/18670	0.1076	0.2854	0.2128	EZR/RAPGEF6/FXYD5/PLD1/RDX/RAPGEF2/ATP8B1/KLF5/FSCN1	9
BP	GO:0030575	nuclear body organization	9/7096	16/18670	0.1076	0.2854	0.2128	HABP4/ZPR1/SRPK2/PML/SUMO1/ETS1/USPL1/DYRK3/CELF3	9
BP	GO:0030889	negative regulation of B cell proliferation	9/7096	16/18670	0.1076	0.2854	0.2128	LYN/MNDA/TNFRSF21/CASP3/TYROBP/CTLA4/ATM/CD300A/TNFRSF13B	9
BP	GO:0032604	granulocyte macrophage colony-stimulating factor production	9/7096	16/18670	0.1076	0.2854	0.2128	LILRA2/DDX58/IL1B/RASGRP1/IL18/CD84/IL12B/CD80/IL23A	9
BP	GO:0033033	negative regulation of myeloid cell apoptotic process	9/7096	16/18670	0.1076	0.2854	0.2128	NOD2/CLEC5A/IRF7/KITLG/MIF/CCL5/CCR5/BCL2/CXCR2	9
BP	GO:0034116	positive regulation of heterotypic cell-cell adhesion	9/7096	16/18670	0.1076	0.2854	0.2128	FLOT1/CD44/TNF/IL1B/AGER/BMP7/LCK/SKAP1/GCNT2	9
BP	GO:0035461	vitamin transmembrane transport	9/7096	16/18670	0.1076	0.2854	0.2128	SLC19A2/SLC23A2/SLC25A19/FOLR2/SCARB1/SLC46A1/SLC5A6/SLC25A32/STRA6	9
BP	GO:0044827	modulation by host of viral genome replication	9/7096	16/18670	0.1076	0.2854	0.2128	IFI27/CCL8/TBC1D20/CCNK/FMR1/FBXL2/EIF2AK4/PPIB/NUCKS1	9
BP	GO:0045623	negative regulation of T-helper cell differentiation	9/7096	16/18670	0.1076	0.2854	0.2128	ANXA1/BCL6/SMAD7/IL4R/SOCS5/ZBTB7B/HLX/TNFSF4/TBX21	9
BP	GO:0048385	regulation of retinoic acid receptor signaling pathway	9/7096	16/18670	0.1076	0.2854	0.2128	CTBP2/EZH2/AKR1C3/TRIM16/DHRS3/CYP26B1/CALR/CYP26A1/CRABP2	9
BP	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter	9/7096	16/18670	0.1076	0.2854	0.2128	SYT11/RAB3GAP1/DOC2B/ATP2A2/SYT1/SYT2/SYT4/SYT5/RIMS2	9
BP	GO:0048820	hair follicle maturation	9/7096	16/18670	0.1076	0.2854	0.2128	RBPJ/WNT5A/MYO5A/NSUN2/ERCC2/CDH3/TRPC4AP/WNT10B/NOM1	9
BP	GO:0050655	dermatan sulfate proteoglycan metabolic process	9/7096	16/18670	0.1076	0.2854	0.2128	VCAN/CSGALNACT1/CSPG4/IDUA/CHST14/CSGALNACT2/BCAN/CHST12/B3GAT3	9
BP	GO:0055119	relaxation of cardiac muscle	9/7096	16/18670	0.1076	0.2854	0.2128	SLC8A1/ATP1A1/RGS2/PDE4B/ATP1B1/CAMK2D/ATP2A2/HRC/ATP1A2	9
BP	GO:0071380	cellular response to prostaglandin E stimulus	9/7096	16/18670	0.1076	0.2854	0.2128	PTGER4/PTGER2/GNB1/P2RY6/GNG2/AKAP8/TNFSF4/PRKAA1/P2RY4	9
BP	GO:0090153	regulation of sphingolipid biosynthetic process	9/7096	16/18670	0.1076	0.2854	0.2128	TNF/PRKCD/SAMD8/ORMDL2/SPHK1/ORMDL3/PRKAA1/PLA2G6/SMPD2	9
BP	GO:0097067	cellular response to thyroid hormone stimulus	9/7096	16/18670	0.1076	0.2854	0.2128	GCLM/CTSS/GAS2L1/RDX/LMO2/GCLC/CTSB/KLF9/PPARGC1A	9
BP	GO:1904294	positive regulation of ERAD pathway	9/7096	16/18670	0.1076	0.2854	0.2128	BCAP31/EDEM1/SGTA/EDEM2/RNFT1/UBQLN2/NFE2L2/ATXN3/RNF185	9
BP	GO:1905038	regulation of membrane lipid metabolic process	9/7096	16/18670	0.1076	0.2854	0.2128	TNF/PRKCD/SAMD8/ORMDL2/SPHK1/ORMDL3/PRKAA1/PLA2G6/SMPD2	9
BP	GO:2000303	regulation of ceramide biosynthetic process	9/7096	16/18670	0.1076	0.2854	0.2128	TNF/PRKCD/SAMD8/ORMDL2/SPHK1/ORMDL3/PRKAA1/PLA2G6/SMPD2	9
BP	GO:2000651	positive regulation of sodium ion transmembrane transporter activity	9/7096	16/18670	0.1076	0.2854	0.2128	CHP1/ACTN4/SLC9A1/TESC/DMD/DNM2/ATP1B1/KIF5B/WNK2	9
BP	GO:2001224	positive regulation of neuron migration	9/7096	16/18670	0.1076	0.2854	0.2128	FLNA/PLAA/RAPGEF2/SRGAP2C/ARHGEF2/ZNF609/KIF20B/NSMF/RELN	9
BP	GO:0030178	negative regulation of Wnt signaling pathway	89/7096	210/18670	0.1077	0.2854	0.2128	MAD2L2/WNT5A/PSMB9/KLHL12/PSMB8/EGR1/PSMA5/DVL2/PSMD11/APOE/GSK3B/PSME1/PTPRO/PSMB10/IGFBP4/TLE1/PSMA1/MCC/PSMA4/ROR2/LATS1/CBY1/RUVBL2/IFT80/FUZ/BMP2/TLE4/PSMB1/EMD/PSMC4/NLK/SFRP4/PSMD13/LRP1/IGFBP2/PSMB3/TMEM170B/CYLD/MESP1/RNF213/TSKU/PSMB5/PSMD6/GRB10/CSNK1A1/WWOX/PSMC3/TMEM64/NPHP4/PSME3/NFATC1/PSMC6/TLE6/TMEM88/NKD2/C12orf43/FZD1/DKK2/DVL1/RNF43/TCF7L2/CTHRC1/PSMC1/PSMD8/PSMA2/LATS2/ANKRD6/JADE1/PFDN5/PSMC5/PSMC2/PSMB2/PSMD4/RBX1/SDHAF2/KREMEN1/LRP4/PSMD1/SFRP5/PSMB4/GREM1/APCDD1/PSMD9/PSMD3/BARX1/SIAH2/CXXC4/HIC1/FOXO3	89
BP	GO:0007160	cell-matrix adhesion	95/7096	225/18670	0.1077	0.2854	0.2128	S100A10/FN1/BST1/TSC1/ITGB7/ITGB5/BCL6/CIB1/CD44/TRIP6/LDB1/VCL/SLC9A1/GSK3B/THBS3/DUSP3/PEAK1/CD36/PTK2B/ITGAL/ADAM15/SRF/ACTN1/CD63/NINJ1/ITGA4/ITGA7/VEGFA/CDK5/ABL1/ITGA11/EPDR1/MMP12/TESK2/LRP1/PPM1F/SLK/RAC1/ADAMTS12/SNED1/TIMM10B/PTK2/ARHGAP6/BCR/LIMCH1/ZYX/EDA/HPSE/CD96/BCL2L11/EMP2/NRP1/DISC1/BCL2/WDPCP/L1CAM/SERPINE1/BCAS3/MADCAM1/ITGA2/ITGA3/MMP14/DMTN/CORO1C/CLASP2/RCC2/JAM3/ADAM9/MKLN1/ITGA8/SKAP1/HRG/BCAM/CD34/NID1/PRKCZ/SIGLEC1/LYVE1/MAP4K4/RHOA/LIMS1/DAG1/CX3CL1/ITGB1BP1/MSLN/CCR7/CD3E/ROCK2/TMEM8B/HOXA7/MACF1/ADAMTS9/PIK3CB/PTPRJ/FMN1	95
BP	GO:0002719	negative regulation of cytokine production involved in immune response	13/7096	25/18670	0.1093	0.2886	0.2152	BCL6/SMAD7/HFE/TNF/IRAK3/HMOX1/LILRB1/TGFB1/HLA-F/CD96/APOA1/TGFB3/TBX21	13
BP	GO:0003309	type B pancreatic cell differentiation	13/7096	25/18670	0.1093	0.2886	0.2152	DLL1/WNT5A/GSK3B/RFX3/BMP5/BMP4/PDX1/CLOCK/BAD/ARNTL/MEN1/SIDT2/SMO	13
BP	GO:0008334	histone mRNA metabolic process	13/7096	25/18670	0.1093	0.2886	0.2152	LSM11/SNRPB/DCP2/CPSF3/ATM/MTPAP/XRN1/SNRPF/SSB/CPSF2/SNRPG/ZNF473/UPF1	13
BP	GO:0009404	toxin metabolic process	13/7096	25/18670	0.1093	0.2886	0.2152	ACAA1/CYP1B1/AKR7A3/ETHE1/PAM/CYP1A2/MPST/CTH/AS3MT/ARL1/NFE2L2/FMO2/CYP2W1	13
BP	GO:0045672	positive regulation of osteoclast differentiation	13/7096	25/18670	0.1093	0.2886	0.2152	FOS/ATP6AP1/KLF10/TNF/TRAF6/CREB1/TYROBP/TMEM64/TREM2/IFNG/IL12B/SLC9B2/IL23A	13
BP	GO:0045956	positive regulation of calcium ion-dependent exocytosis	13/7096	25/18670	0.1093	0.2886	0.2152	STXBP1/UNC13B/CDK5/DOC2B/ARF1/HYAL3/DNM1L/CDK5R2/SYT9/SYT1/SYT4/SCAMP5/CACNA1H	13
BP	GO:0046856	phosphatidylinositol dephosphorylation	13/7096	25/18670	0.1093	0.2886	0.2152	SACM1L/SYNJ1/SYNJ2/OCRL/MTMR4/INPP5K/MTMR6/MTMR2/INPP5F/MTMR3/MTMR9/INPPL1/INPP5A	13
BP	GO:0051894	positive regulation of focal adhesion assembly	13/7096	25/18670	0.1093	0.2886	0.2152	S100A10/TSC1/VEGFA/ABL1/PPM1F/RAC1/NRP1/HRG/MAP4K4/LIMS1/ITGB1BP1/PTPRJ/FMN1	13
BP	GO:0000387	spliceosomal snRNP assembly	25/7096	53/18670	0.1094	0.2886	0.2152	DDX20/SRSF10/COIL/SNUPN/SNRPB/GEMIN6/GEMIN7/CD2BP2/SNRPD1/PRPF3/USP4/SNRPC/STRAP/SNRPF/PRPF8/PRMT5/AAR2/TGS1/PRPF31/SART1/WDR77/CLNS1A/PRPF19/SNRPG/SNRPD2	25
BP	GO:0038066	p38MAPK cascade	25/7096	53/18670	0.1094	0.2886	0.2152	EZR/DUSP1/ZFP36/DUSP10/MAP3K4/GADD45B/HGF/LEP/NCF1/PTPN22/BMP2/VEGFA/IL1B/AGER/MFHAS1/CYLD/RELL2/SPHK1/MAPKAPK2/LGALS9/MAP3K5/CAV3/ULK4/PRMT1/SASH1	25
BP	GO:0051494	negative regulation of cytoskeleton organization	64/7096	148/18670	0.1095	0.2887	0.2152	MYADM/STMN1/ARAP1/S1PR1/CIB1/TMSB10/TMOD3/KAT2B/LIMA1/TRIM37/TWF2/RDX/PFN1/CAPZA2/SWAP70/PRKCD/GMFG/CORO1A/ARFGEF1/CAPG/NPM1/CDK5RAP2/ARHGEF2/CAPZA1/MAPRE1/MKKS/ARPIN/SPTBN1/CDH5/CORO1B/ARHGAP6/BBS4/AVIL/CHMP2A/INPP5K/KANK1/TRIOBP/ADD3/SHANK1/DMTN/CLASP2/LMOD3/BRCA1/CAV3/SCIN/SLIT2/TUBB4A/KAT2A/KATNB1/SPTA1/SPTBN2/TACSTD2/TMEFF2/KANK3/NAV3/PICK1/SNCA/CLIP3/TTBK2/MET/FGF13/WAS/SHANK3/CCNF	64
BP	GO:0006261	DNA-dependent DNA replication	66/7096	153/18670	0.1101	0.2901	0.2163	ATG7/BAZ1A/BCL6/MCM6/FBXW7/GINS1/MCM2/SLFN11/GMNN/ALYREF/ZNF830/ORC5/RPA1/SSBP1/ETAA1/DBF4B/SETMAR/PRIM2/PURA/POLD4/ZPR1/WRNIP1/DSCC1/HMGA1/SAMHD1/DONSON/POLD2/TIPIN/CDK9/RFC3/RNASEH1/POLG/CCNE1/PCNA/ORC6/BOD1L1/RFWD3/GEN1/TIMELESS/RECQL/ORC4/TICRR/ZMPSTE24/GINS4/RRM2B/MCM5/FANCM/RTEL1/POLD1/SMC3/POLA1/POLA2/ORC3/LIG3/POLB/POLE4/MCMBP/ATAD5/TONSL/PNKP/NUCKS1/FEN1/RECQL4/ZRANB3/E2F8/UPF1	66
BP	GO:0030168	platelet activation	66/7096	153/18670	0.1101	0.2901	0.2163	FYN/PTPN6/CLIC1/MYL12A/LYN/DGKA/PLSCR1/GNB1/FLNA/CD40/GNA15/VCL/SLC7A11/APOE/LCP2/AXL/ACTB/TLN1/STXBP1/ITPR1/DGKD/ARRB1/GNAQ/HSPB1/PRKCD/SRF/HBB/TSPAN32/TLR4/FIBP/RAP2B/PLCG2/TREML1/PIK3R6/P2RY12/THBD/RAF1/IL6/LCK/PDGFB/GNG2/MYH9/P2RX1/BLOC1S3/TEC/PLEK/PDGFA/VWF/DMTN/F2R/BLOC1S4/VAV1/MERTK/MAPK1/GNA13/DGKG/HRG/PIK3CG/STXBP3/CSRP1/PRKCQ/TYRO3/PRKCA/GNA11/P2RY1/PIK3CB	66
BP	GO:0097479	synaptic vesicle localization	70/7096	163/18670	0.1111	0.2927	0.2182	APBA1/PINK1/STX11/DNM3/RAP1B/SYT11/BLOC1S2/P2RX7/CTBP2/GSK3B/STXBP1/UNC13B/SYNJ1/FBXL20/AP3M2/CDK5/RAB3GAP1/TMEM230/DTNBP1/RAP1A/BLOC1S6/DOC2B/PREPL/LRRK2/ADCY1/ARF1/TOR1A/DNM1/P2RX1/ADORA2B/VPS18/NAPA/DNM2/BLOC1S3/RAB5A/CAMK2A/CHRM2/DNM1L/BLOC1S1/CHRNA4/BLOC1S4/AP3B1/ATP2A2/DVL1/PSEN1/FMR1/RAB3A/CHRNB2/P2RY4/PPFIA3/SYT9/AP3M1/SYT1/SYT2/VAMP1/DOC2A/SNAP29/SYT4/CADPS2/SYT5/BRSK1/SNCA/RIMS2/WNT7A/PICALM/NLGN2/SYN3/RAB27A/P2RY1/TRIM46	70
BP	GO:2000027	regulation of animal organ morphogenesis	106/7096	253/18670	0.112	0.2949	0.2199	VDR/RBPJ/POR/WNT5A/CELSR2/PIM1/PSMB9/TNFAIP3/PSMB8/FBXW7/STAT1/LGR4/MYC/MAGED1/PSMA5/DVL2/TNF/PSMD11/PSME1/TGFB1/DAAM1/PFN1/HGF/PSMB10/PSMA1/PSMA4/ROR2/BMP2/VEGFA/ABL1/PAX8/PSMB1/SAPCD2/PSMC4/PSMD13/PSMB3/BASP1/BMP7/RAC1/ETV5/MESP1/FGF1/CITED2/BCOR/SULF2/PSMB5/PSMD6/PSMC3/RXRA/AP2A2/BMPR1A/PSME3/BCL2/BMP4/BAX/PSMC6/SRSF6/ROR1/AP2S1/PDGFA/MKS1/FZD5/HES1/SPRY1/AP2A1/FZD1/CNTF/CAV3/FZD4/DVL1/WNT1/CTHRC1/PSMC1/HNF1B/PSMD8/PSMA2/BTBD7/CD34/ANKRD6/FZD7/TACSTD2/WNT2B/CARM1/MSX1/PSMC5/PSMC2/AP2M1/GPC4/PSMB2/PSMD4/HPN/RHOA/WNT6/ENG/FZD2/GRHL3/WNT10A/PSMD1/WNT7A/PSMB4/GREM1/SMO/WT1/PSMD9/PSMD3/BMPR2	106
BP	GO:0051283	negative regulation of sequestering of calcium ion	55/7096	126/18670	0.1123	0.2956	0.2204	SLC8A1/HTR2B/PTPN6/LYN/MCOLN1/TPCN1/DIAPH1/CXCL9/CXCL11/PTPRC/P2RX7/CXCL10/PKD2/TGFB1/ITPR1/PTK2B/MYO5A/CORO1A/P2RY6/RYR1/ABL1/GSTO1/PLCG2/DMD/TRPM2/LCK/CCR5/SRI/RASA3/ANXA6/BAX/PRKACA/CYBA/MCOLN2/F2R/CAMK2D/PLCB1/CEMIP/LETM1/CASQ1/CAPN3/CASQ2/HRC/BDKRB1/TMEM38B/LACRT/LIME1/SNCA/CX3CL1/CCL19/CHERP/ATP1A2/CCR7/MCOLN3/NTSR1	55
BP	GO:0021953	central nervous system neuron differentiation	78/7096	183/18670	0.1124	0.2959	0.2206	NR4A2/WNT5A/TCTN1/ATF5/LDB1/IFT172/EPHB2/GIGYF2/ZEB2/ZSWIM6/BTG2/SIN3A/CLN8/TULP3/RAPGEF2/LEP/CSNK1D/SCN1B/B4GALT6/FBXO45/ADARB1/CDK5/PAFAH1B1/OPHN1/SATB2/EVX1/CRK/ABT1/DCC/TAL1/MYCBP2/MDGA1/TSKU/PTK2/ARX/CSNK1E/GDPD5/DCLK2/NRP1/DISC1/NRP2/NDEL1/INHBA/B4GALT5/UQCRQ/HES1/FZD1/NFE2L1/BCL11B/SLIT2/WNT1/PSEN1/CBLN1/CHRNB2/RORA/EPHB1/PLXNA3/SPOCK1/FAIM2/ATP7A/HSP90AB1/KNDC1/NR2E1/CSF1R/C21orf91/PAX7/SOX4/LMX1A/WNT7A/OTP/AGTPBP1/SMO/SHANK3/LHX6/PTCH1/MDGA2/NTRK2/ZNF335	78
BP	GO:1905954	positive regulation of lipid localization	37/7096	82/18670	0.1126	0.2961	0.2208	RETN/ATP8A1/SPP1/MIF/SCARB1/P2RX7/NFKBIA/SCP2/NFKB1/APOE/PRELID1/CD36/NR1H2/PRKCD/ABCA1/IL1B/ACACB/LRP1/EHD1/TNFRSF11A/SIRT1/FABP3/ABCG1/NR1H3/ABCB4/SREBF2/ABCA7/ANXA2P2/GALR1/APOA1/PLA2G6/ANXA2/TRIAP1/VSTM2A/PTCH1/NTSR1/GHRL	37
BP	GO:0051783	regulation of nuclear division	80/7096	188/18670	0.1126	0.2961	0.2208	IGF1/DUSP1/MAD2L2/WNT5A/NUP62/DYNC1LI1/RGCC/SPDL1/LRP5/CHMP4B/RAD1/TGFB1/SMC5/INSR/CENPE/NAA10/UBXN2B/KLHL22/CDK5RAP2/IL1B/NSMCE2/TOM1L1/NSFL1C/CDKN1C/PHIP/TOM1L2/BMP7/PDGFB/CDC23/RCC1/ESPL1/ZNF207/LCMT1/ATM/ANAPC5/BUB3/SPHK1/NDC80/BMP4/CHMP2A/CDKN1B/KIF20B/MAD2L1BP/IL1A/GEN1/NUSAP1/ZW10/CHMP1A/VPS4B/UBE2C/PRMT5/CALR/MOS/NFE2L1/CDC26/PLCB1/RIOK2/DLGAP5/SMC3/ANAPC4/MTBP/MKI67/CDC27/CDC20/PIN1/PCID2/RB1/STAG1/MSX1/CUL9/AURKAIP1/AURKA/ANAPC11/IK/CHMP1B/UBE2B/CCDC8/CEP85/HORMAD1/L3MBTL1	80
BP	GO:0007616	long-term memory	16/7096	32/18670	0.1128	0.2962	0.2208	APOE/SRF/LDLR/ARC/ADCY1/RGS14/SHANK1/CPEB3/NPAS4/RASGRF1/KAT2A/EIF2AK4/PRKCZ/RELN/MTOR/CTNS	16
BP	GO:0050779	RNA destabilization	16/7096	32/18670	0.1128	0.2962	0.2208	ZFP36/YTHDF3/MOV10/HNRNPR/METTL14/GIGYF2/METTL3/ZC3H12D/FTO/HNRNPD/CPEB3/ZFP36L2/DXO/ROCK2/PLEKHN1/UPF1	16
BP	GO:0071353	cellular response to interleukin-4	16/7096	32/18670	0.1128	0.2962	0.2208	IL2RG/NFIL3/STAT6/PTPN2/KEAP1/MCM2/IL4R/CDK4/ALAD/CORO1A/HSPA5/CD300LF/PML/DCSTAMP/TUBA1B/HSP90AB1	16
BP	GO:0090504	epiboly	16/7096	32/18670	0.1128	0.2962	0.2208	ITGA5/FLNA/RHOC/CD44/MEGF8/CD151/MMP12/TOR1A/CLASP2/ADAM17/HBEGF/TMEFF2/MTOR/RHOA/PDCD10/WNT7A	16
BP	GO:0007257	activation of JUN kinase activity	19/7096	39/18670	0.1132	0.2968	0.2212	WNT5A/ERCC6/MAP4K5/MAP3K12/MDFIC/MAP4K2/MAP3K6/MAP4K1/MLKL/MAP3K11/BIRC7/MAP3K5/MUL1/MAP2K4/MAP3K13/ERN1/CCL19/DAXX/MAP3K9	19
BP	GO:0030501	positive regulation of bone mineralization	19/7096	39/18670	0.1132	0.2968	0.2212	SLC8A1/ACVR2B/ATRAID/P2RX7/TGFB1/FZD9/BMP2/ISG15/BMP7/BMPR1A/BMP4/ADRB2/KL/TGFB3/TMEM119/WNT10B/BMPR1B/MEF2C/BMPR2	19
BP	GO:0045684	positive regulation of epidermis development	19/7096	39/18670	0.1132	0.2968	0.2212	VDR/WNT5A/PPARD/TNF/TRIM16/NCOA3/SFN/PTCH2/SFRP4/TRADD/ALOX15B/HPSE/BMP4/KRT10/CYP27B1/TMEM79/FOXN1/WNT10B/PTCH1	19
BP	GO:0007004	telomere maintenance via telomerase	32/7096	70/18670	0.1143	0.2993	0.2231	MAP3K4/RPA1/PKIB/NAF1/HNRNPA1/XRCC5/DCP2/NAT10/PTGES3/ATM/TNKS1BP1/MAPKAPK5/NHP2/HNRNPC/XRN1/GAR1/CCT4/FBXO4/CCT8/ATR/MAPK1/TELO2/ACD/CTC1/GNL3L/HSP90AB1/TERT/PRKCQ/POT1/NOP10/PNKP/NEK7	32
BP	GO:0010517	regulation of phospholipase activity	32/7096	70/18670	0.1143	0.2993	0.2231	HTR2B/S1PR4/ANXA1/FLT1/GNA15/RGS2/PLAA/PTAFR/GNAQ/LPAR2/ARF4/P2RY6/HRAS/ABL1/CCL5/P2RY12/LRP1/ITK/BICD1/ARHGAP6/NMUR2/ARL1/LPAR1/EGFR/ABL2/GNA13/TXK/PRKCZ/SNCA/ADCYAP1R1/RASGRP4/NTRK2	32
BP	GO:0033077	T cell differentiation in thymus	32/7096	70/18670	0.1143	0.2993	0.2231	SOD1/JMJD6/EGR3/PTPN2/PTPRC/ADAM8/CD74/IL7R/SRF/ZBTB1/NFKBID/CD3D/RASGRP1/CLPTM1/TESPA1/VNN1/BCL2/BMP4/CCR6/CD3G/LIG4/FZD5/ADA/FADD/ADAM17/BCL11B/WNT1/ZFP36L2/FZD7/FOXN1/CCR7/CD3E	32
BP	GO:0045834	positive regulation of lipid metabolic process	63/7096	146/18670	0.1156	0.3009	0.2244	FPR2/HTR2B/NOD2/SLC27A1/ANXA1/LYN/POR/STARD4/FLT1/CAPN2/PTGS2/SIRT4/ABHD6/RDH10/ATG14/SLC45A3/APOC1/SCARB1/TNF/CD74/ELOVL5/APOE/LPGAT1/TGFB1/PTK2B/NR1H2/PRKCD/FLT3/FGR/IL1B/LDLR/P2RY12/CREB1/CREBL2/DGAT2/FABP3/IRS2/PDGFB/PPARGC1A/EPHA8/FGF1/RAB38/MLYCD/APOA5/PTK2/ABCG1/NR1H3/CPT1A/EEF1A2/PPARA/PRKAA1/APOA1/PLA2G6/IFNG/NR4A3/ZBTB20/MTOR/TAZ/ABCD1/CCL19/SMPD2/CCR7/NR1H4	63
BP	GO:0006878	cellular copper ion homeostasis	8/7096	14/18670	0.1162	0.3009	0.2244	SCO2/SLC31A2/ATOX1/COX19/ATP7B/ARF1/ATP7A/APP	8
BP	GO:0006896	Golgi to vacuole transport	8/7096	14/18670	0.1162	0.3009	0.2244	LAMP1/GOSR2/VPS52/VTI1A/AP1G1/VTI1B/EHD3/CCDC91	8
BP	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity	8/7096	14/18670	0.1162	0.3009	0.2244	CBLB/SOCS5/ZFYVE28/ZGPAT/SNX6/TSG101/VPS25/PSEN1	8
BP	GO:0015780	nucleotide-sugar transmembrane transport	8/7096	14/18670	0.1162	0.3009	0.2244	SLC35B4/SLC35D1/SLC35B1/SLC35A3/SLC35C1/SLC35A5/SLC35A2/SLC35D2	8
BP	GO:0021692	cerebellar Purkinje cell layer morphogenesis	8/7096	14/18670	0.1162	0.3009	0.2244	DLL1/LDB1/RORA/FAIM2/ATP7A/SPTBN2/AGTPBP1/KIF14	8
BP	GO:0030207	chondroitin sulfate catabolic process	8/7096	14/18670	0.1162	0.3009	0.2244	HEXB/VCAN/IDS/HEXA/ARSB/CSPG4/IDUA/BCAN	8
BP	GO:0032048	cardiolipin metabolic process	8/7096	14/18670	0.1162	0.3009	0.2244	SLC27A1/HADHB/PTPMT1/CRLS1/HADHA/PLA2G6/TAZ/PGS1	8
BP	GO:0032802	low-density lipoprotein particle receptor catabolic process	8/7096	14/18670	0.1162	0.3009	0.2244	APOE/FURIN/AP2A2/AP2S1/AP2A1/ANXA2P2/AP2M1/ANXA2	8
BP	GO:0035020	regulation of Rac protein signal transduction	8/7096	14/18670	0.1162	0.3009	0.2244	ARF6/ALS2/KRAS/STMN3/CRK/DNM2/RASGRF1/OGT	8
BP	GO:0043173	nucleotide salvage	8/7096	14/18670	0.1162	0.3009	0.2244	UPP1/ADK/AMPD2/ADA/UCK1/UCKL1/UPP2/AMPD3	8
BP	GO:0043455	regulation of secondary metabolic process	8/7096	14/18670	0.1162	0.3009	0.2244	WNT5A/SLC7A11/ZEB2/PGAM1/RAPGEF2/ASIP/CDH3/APPL1	8
BP	GO:0045605	negative regulation of epidermal cell differentiation	8/7096	14/18670	0.1162	0.3009	0.2244	DLL1/EZH2/SRSF6/HES1/CDSN/REG3G/HOXA7/GRHL2	8
BP	GO:0045651	positive regulation of macrophage differentiation	8/7096	14/18670	0.1162	0.3009	0.2244	HCLS1/TGFB1/ROR2/CASP8/ID2/FADD/RB1/PRKCA	8
BP	GO:0046479	glycosphingolipid catabolic process	8/7096	14/18670	0.1162	0.3009	0.2244	HEXB/GM2A/PSAP/GALC/PRKCD/GLA/NAGA/NEU1	8
BP	GO:0046606	negative regulation of centrosome cycle	8/7096	14/18670	0.1162	0.3009	0.2244	KAT2B/TRIM37/NPM1/CDK5RAP2/CHMP2A/BRCA1/KAT2A/CCNF	8
BP	GO:0050720	interleukin-1 beta biosynthetic process	8/7096	14/18670	0.1162	0.3009	0.2244	AZU1/JAK2/EGR1/AGER/TYROBP/CMA1/IFNG/APP	8
BP	GO:0051547	regulation of keratinocyte migration	8/7096	14/18670	0.1162	0.3009	0.2244	ARF6/IQSEC1/MAPRE2/MMP9/ADAM9/HBEGF/MAP4K4/MTOR	8
BP	GO:0051712	positive regulation of killing of cells of other organism	8/7096	14/18670	0.1162	0.3009	0.2244	CLEC7A/GAPDH/BCL2L11/FCER2/PGLYRP4/PRF1/BAD/IFNG	8
BP	GO:0055064	chloride ion homeostasis	8/7096	14/18670	0.1162	0.3009	0.2244	SLC12A9/SLC12A2/SLC12A8/SLC12A1/SLC12A7/ATP6V1B1/SLC12A4/SLC12A6	8
BP	GO:0060211	regulation of nuclear-transcribed mRNA poly(A) tail shortening	8/7096	14/18670	0.1162	0.3009	0.2244	ZFP36/TOB1/AGO2/BTG2/TNRC6B/TNRC6A/CPEB3/CNOT7	8
BP	GO:0072216	positive regulation of metanephros development	8/7096	14/18670	0.1162	0.3009	0.2244	MYC/EGR1/PAX8/BASP1/PDGFB/PDGFA/RET/WT1	8
BP	GO:0080009	mRNA methylation	8/7096	14/18670	0.1162	0.3009	0.2244	TRMT6/METTL14/METTL3/TRMT61B/CBLL1/CMTR1/CMTR2/TRMT10C	8
BP	GO:0098543	detection of other organism	8/7096	14/18670	0.1162	0.3009	0.2244	NOD2/TLR1/TLR2/CLEC7A/TLR4/CD1D/PGLYRP4/TLR6	8
BP	GO:1901722	regulation of cell proliferation involved in kidney development	8/7096	14/18670	0.1162	0.3009	0.2244	MYC/EGR1/BMP7/PDGFB/FLCN/BMP4/WT1/PDGFD	8
BP	GO:1904263	positive regulation of TORC1 signaling	8/7096	14/18670	0.1162	0.3009	0.2244	SEH1L/KLHL22/RRAGD/FLCN/RRAGA/LAMTOR5/TELO2/CLEC16A	8
BP	GO:1905516	positive regulation of fertilization	8/7096	14/18670	0.1162	0.3009	0.2244	PLB1/CCDC87/FAM170B/HYAL3/PLCB1/LHFPL2/CACNA1H/POMZP3	8
BP	GO:0034329	cell junction assembly	101/7096	241/18670	0.1176	0.3044	0.227	S100A10/FN1/VASP/MPP5/TSC1/ITGA5/RAP1B/PLEC/FLNA/SMAD7/FBLIM1/RHOC/LSR/ACTN4/FLOT1/TRIP6/F11R/CBFB/LDB1/VCL/TNF/SLC9A1/PTPRO/DUSP3/PEAK1/ACTB/TLN1/CTNNA1/RAPGEF2/PTK2B/HEG1/SRF/ACTN1/LAMB3/VEGFA/ABL1/OPHN1/CD151/CAPZA1/STRN/RAP1A/TESK2/LRP1/GPBAR1/PPM1F/SLK/SH3BP1/RAC1/CDH5/MYO1C/FLCN/PTK2/ARHGAP6/BCR/LIMCH1/NPHP4/HDAC7/NRP1/BCL2/ZNF703/WDPCP/BCAS3/MICALL2/TLN2/PRKACA/ITGA2/FZD5/PARD6B/HIPK1/MMP14/DMTN/CORO1C/CLASP2/PKN2/RCC2/CDH17/MPP7/FSCN1/CDH10/SNAI1/GNPAT/PKP2/HRG/MTDH/MAP4K4/RHOA/TRPV4/KRT14/CDH3/LIMS1/CDHR3/ITGB1BP1/ROCK2/GJA1/NR1H4/PRKCA/CDH26/GRHL2/MACF1/PTPRJ/FMN1	101
BP	GO:0002712	regulation of B cell mediated immunity	24/7096	51/18670	0.1179	0.3049	0.2273	PTPN6/IL27RA/MAD2L2/STAT6/BCL6/CD40/PTPRC/TNF/CD226/TGFB1/HLA-E/CR1/FCER2/MLH1/PARP3/CLCF1/TFRC/TNFSF4/EXOSC3/TBX21/APLF/EXOSC6/PAXIP1/ATAD5	24
BP	GO:0002889	regulation of immunoglobulin mediated immune response	24/7096	51/18670	0.1179	0.3049	0.2273	PTPN6/IL27RA/MAD2L2/STAT6/BCL6/CD40/PTPRC/TNF/CD226/TGFB1/HLA-E/CR1/FCER2/MLH1/PARP3/CLCF1/TFRC/TNFSF4/EXOSC3/TBX21/APLF/EXOSC6/PAXIP1/ATAD5	24
BP	GO:0031103	axon regeneration	24/7096	51/18670	0.1179	0.3049	0.2273	KLF4/RTN4R/GRN/LRIG2/SPP1/MAP2K1/MTR/LAMB2/JAK2/CERS2/NREP/CTNNA1/LRP1/BCL2/NDEL1/INPP5F/RTN4RL1/CNTF/DHFR/JAM3/APOA1/RTN4RL2/DAG1/KREMEN1	24
BP	GO:0009226	nucleotide-sugar biosynthetic process	12/7096	23/18670	0.1188	0.3065	0.2285	PGM3/GNPDA1/UAP1/NAGK/RENBP/PMM2/SLC35D1/GNPNAT1/UAP1L1/GFPT1/GFPT2/GMDS	12
BP	GO:0015813	L-glutamate transmembrane transport	12/7096	23/18670	0.1188	0.3065	0.2285	SLC38A7/PER2/SLC7A11/CLN8/ARL6IP1/PRAF2/SLC25A12/SLC25A13/PSEN1/SLC25A22/ATP1A2/NTSR1	12
BP	GO:0032799	low-density lipoprotein receptor particle metabolic process	12/7096	23/18670	0.1188	0.3065	0.2285	APOE/HNRNPK/FURIN/AP2A2/SCAP/AP2S1/AP2A1/ANXA2P2/AP2M1/ANXA2/SEC24A/CNPY2	12
BP	GO:0036037	CD8-positive, alpha-beta T cell activation	12/7096	23/18670	0.1188	0.3065	0.2285	IRF1/SH3RF1/CBFB/HFE/LILRB1/ZBTB7B/HLA-E/BCL2/GPR18/CD274/SOCS1/TNFSF8	12
BP	GO:0089718	amino acid import across plasma membrane	12/7096	23/18670	0.1188	0.3065	0.2285	RGS2/PER2/SLC7A11/CLN8/ARL6IP1/SLC7A1/SLC6A5/SLC36A4/PSEN1/SLC7A2/ATP1A2/NTSR1	12
BP	GO:2000637	positive regulation of gene silencing by miRNA	12/7096	23/18670	0.1188	0.3065	0.2285	ZFP36/STAT3/MAP2K1/AGO2/TGFB1/DHX9/PUM2/BMP4/MAP2K2/EGFR/FMR1/EIF4G1	12
BP	GO:0007098	centrosome cycle	54/7096	124/18670	0.119	0.3067	0.2286	NUP62/ATF5/ODF2/PKD2/HAUS8/KAT2B/CHMP4B/TRIM37/KIF3B/CETN3/PCM1/CEP131/SASS6/UBXN2B/PLK2/NPM1/CDK5RAP2/KIAA0753/NSFL1C/CEP76/CNTLN/BBS4/SYNE2/HAUS2/SPICE1/CHMP2A/CKAP5/SLC16A1/CEP152/NDEL1/GEN1/CHMP1A/VPS4B/PARD6B/CEP63/BRCA1/CETN1/CETN2/HAUS5/CHORDC1/HAUS1/KAT2A/PKHD1/CEP120/AURKA/BRSK1/SAC3D1/UXT/CHMP1B/ROCK2/CEP85/C2CD3/ALMS1/CCNF	54
BP	GO:0051209	release of sequestered calcium ion into cytosol	54/7096	124/18670	0.119	0.3067	0.2286	SLC8A1/HTR2B/PTPN6/LYN/MCOLN1/TPCN1/DIAPH1/CXCL9/CXCL11/PTPRC/P2RX7/CXCL10/PKD2/TGFB1/ITPR1/PTK2B/MYO5A/CORO1A/P2RY6/RYR1/ABL1/GSTO1/PLCG2/DMD/TRPM2/LCK/CCR5/SRI/RASA3/BAX/PRKACA/CYBA/MCOLN2/F2R/CAMK2D/PLCB1/CEMIP/LETM1/CASQ1/CAPN3/CASQ2/HRC/BDKRB1/TMEM38B/LACRT/LIME1/SNCA/CX3CL1/CCL19/CHERP/ATP1A2/CCR7/MCOLN3/NTSR1	54
BP	GO:0044773	mitotic DNA damage checkpoint	43/7096	97/18670	0.1193	0.3072	0.229	CDKN1A/RGCC/HUS1B/GIGYF2/BTG2/TAOK3/ZNF830/SYF2/PLK2/SFN/DONSON/PML/TIPIN/CCND1/ATM/TNKS1BP1/MUC1/PLK3/PCNA/BAX/CRADD/CASP2/RFWD3/CDKN1B/CNOT4/PLAGL1/ARID3A/FOXO4/E2F4/CNOT7/GML/MDM2/CLSPN/RBL2/RAD9A/CNOT10/CARM1/TRIAP1/AURKA/BRSK1/SOX4/PRMT1/E2F8	43
BP	GO:0051591	response to cAMP	43/7096	97/18670	0.1193	0.3072	0.229	CRHBP/SLC8A1/JUNB/FOS/EZR/DUSP1/LDHA/AQP9/FOSB/SRD5A1/RAP1B/JUND/BIRC2/STAT1/PKD2/RELA/PTAFR/RAPGEF2/PTK2B/HSPA5/RAP1A/AHR/THBD/SPARC/HCN4/PFKFB1/INPP5K/NME1/KCNQ1/DMTN/FDX1/FOSL1/PIK3CG/REN/CARM1/APP/PNPT1/HCN1/SLC8A3/WNT10B/ALDH3A1/MMP19/WT1	43
BP	GO:0021700	developmental maturation	118/7096	284/18670	0.1198	0.3085	0.23	IGF1/EPAS1/KLF2/CX3CR1/CDKN1A/CLEC7A/NR4A2/RBPJ/WNT5A/S1PR1/CBFB/DCHS1/IL15/DEFB1/NFIA/THBS3/AXL/FAM210B/REC8/ZBTB7A/STXBP1/KCNIP2/PFN1/UNC13B/HIF1A/POU2F2/PTK2B/MYO5A/LEP/FEM1B/BCL11A/CD63/B4GALT6/RYR1/CEBPA/BMP2/VEGFA/CLCN3/CDKN1C/XYLT1/SEMA4D/BLOC1S6/ANKRD27/NSUN2/RFX3/CDH5/LRRK2/RAB32/G6PD/EPHA8/SPINK1/IGSF21/TAL1/RAB38/LYL1/SLC26A8/DISC1/BCL2/BLOC1S3/ANKRD17/ID2/CCR6/PRKACA/LGI4/TYMS/B4GALT5/CLN5/SHANK1/FZD5/BCAN/HES1/CDK5R2/ARCN1/C1QL1/WNT1/AP1G1/RAB3A/ERCC2/MAP3K13/EPB42/TMEM79/AP1M1/SNX19/TFCP2L1/CDC20/RET/RB1/REN/RXFP2/MMP2/BFSP2/SYT4/RELN/MTOR/MBTPS2/RHOA/CDH3/AURKA/PICK1/APP/DAG1/SRRM4/CX3CL1/CCL19/TRPC4AP/IRX5/TRIM58/ELSPBP1/PICALM/WNT10B/GJA1/GREM1/LHX6/KIF14/NOM1/FOXO3/GLDN/CAMK2B	118
BP	GO:0043462	regulation of ATPase activity	36/7096	80/18670	0.1204	0.3097	0.2309	TSC1/PLSCR1/CHTOP/UHRF1/VCPKMT/PFN1/DNAJB1/DYNLL2/SETMAR/DNAJC19/MYBPC3/DHX9/ATP1B2/DNAJC1/DNAJB6/SUMO1/ATP1B3/GTF2H4/DNAJB4/TMEM64/NAPA/DNM2/TPM1/ATP1B1/OXA1L/DNAJC10/DNAL4/VMA21/DNAJC15/RAB3A/HSCB/PXK/DNAJA1/SLN/SNX16/DNAJC24	36
BP	GO:0097061	dendritic spine organization	36/7096	80/18670	0.1204	0.3097	0.2309	FYN/SIPA1L1/DNM3/LGMN/DOCK10/EPHB2/APOE/ACTR2/LRP8/UBE3A/INSR/BAIAP2/IGF1R/CDK5/PAFAH1B1/HOMER1/CAPRIN1/KALRN/LRRK2/ARC/ARF1/PDLIM5/CFL1/MTMR2/SHANK1/ITGA3/BHLHB9/DNM1L/DVL1/EPHB1/RELN/PICK1/WNT7A/SHANK3/ZMYND8/CAMK2B	36
BP	GO:0006869	lipid transport	150/7096	365/18670	0.1207	0.3102	0.2313	SLC27A1/KCNN4/ANXA1/PLA2G12A/SLC27A3/FABP4/AQP9/STARD4/ATP8B2/RETN/SLCO3A1/ATP8A1/GM2A/NPC2/SPP1/PPARD/MIF/ESYT2/PITPNA/OSBPL9/SLC25A20/PLIN2/APOC1/SCARB1/APOL6/PSAP/P2RX7/SOAT1/NFKBIA/SPNS1/SCP2/CETP/NFKB1/APOE/PRELID1/LIMA1/SLCO2B1/HDLBP/CPT2/CLN8/OSBPL1A/STARD10/ABCD3/CD36/APOO/LEP/NR1H2/PITPNM1/PRKCD/HNRNPK/ATP11B/ACSL4/LRP10/AKR1C1/ATP10A/ABCA1/IL1B/LAMTOR1/LDLR/C2CD2L/SLC27A2/ACACB/LRP1/ATP8B1/TNFRSF11A/STARD7/APOBR/CLU/SIRT1/PDZD8/FABP3/ABCA5/IRS2/ARV1/APOL1/APOA5/PNPLA8/CFHR4/MIR34A/NME4/MFSD2A/PLA2G3/PLEKHA8/PRKAG2/NCOR1/APOL3/NMUR2/LCAT/RXRA/VPS51/ABCG1/NR1H3/APOL2/INHBA/CPT1A/OSBPL2/ABCB4/SLC10A1/SPNS3/KDM5B/ABCB11/SREBF2/UGCG/VPS4B/TEX2/GOT2/CPTP/CHKA/ABCA7/PPARA/NMB/ABCA11P/NUS1/FZD4/ANXA2P2/SLC5A8/PRELID2/GALR1/PLEKHA3/STX12/APOA1/PLA2G6/ABCA6/TMEM30A/REN/LBP/ABCC3/ABCC4/CROT/APOL4/SERAC1/ANXA2/TRIAP1/STARD6/SLCO1C1/APOL5/ABCD1/SIGMAR1/SPX/THRSP/NR1H4/GLTP/RBP4/PTCH1/PLEKHA8P1/ATP10B/NTSR1/GHRL/SLCO1B1/STRA6	150
BP	GO:0006195	purine nucleotide catabolic process	21/7096	44/18670	0.1208	0.3104	0.2314	PNP/ACOT7/HDDC3/NUDT1/NT5C/PDE4B/HINT1/SAMHD1/NUDT9/MLYCD/DNPH1/NUDT3/PDE7A/ADA/NUDT7/GPX1/PDE8A/AMPD3/ABCD1/NUDT16/PDE8B	21
BP	GO:0070897	transcription preinitiation complex assembly	21/7096	44/18670	0.1208	0.3104	0.2314	DR1/THRA/TAF11/PSMC4/TAF12/HMGB1/CREB1/TAF1B/PSMC3/CAND1/PSMC6/TAF6L/TBPL1/GTF3C3/TAF1C/BDP1/PSMC5/PSMC2/TBP/WNT10B/TAF7	21
BP	GO:0009914	hormone transport	133/7096	322/18670	0.121	0.3104	0.2314	CRHBP/SLCO4A1/ANXA1/ACVR2B/LYN/RETN/SPP1/PPARD/HADH/SIRT4/SMAD2/ENY2/PER2/CYB5R4/JAK2/FAM3D/HFE/TNF/HMGCR/DPP4/LRP5/PPP3CB/ITPR1/AACS/ARRB1/HIF1A/FFAR2/PIM3/ENHO/MYO5A/LEP/MCU/AIMP1/TCIRG1/ITSN1/SLC16A10/PAX8/IL1B/UQCC2/CCL5/C2CD2L/RAP1A/MPC2/LRP1/CREB1/RAF1/RFX3/IL1RN/TRPM4/DOC2B/RAC1/GLUD1/IL6/KALRN/IRS2/SLC25A5/KLF7/SERP1/SRI/OXCT1/RPH3AL/GPR27/SLC16A2/SLC16A1/FFAR4/SYTL4/OSM/INHBA/CPT1A/PDX1/KDM5B/TM7SF3/PTPRN2/PFKFB2/HMGN3/RAB8B/EGFR/ICA1/NMB/CLOCK/FZD4/GIPR/GALR1/TCF7L2/EXOC3L1/LTBP4/BAD/SYT9/PLA2G6/HNF1B/SERPINA7/IFNG/HNF1A/ARNTL/VIP/NPVF/SNX19/KIF5B/INHA/SNX4/REN/STXBP3/NDUFAF2/MAP4K4/SCG5/TRPV4/SLCO1C1/GHRH/SLC9B2/SOX4/SIDT2/ARL2BP/RIMS2/GCG/PFKL/FGF23/NLGN2/GJA1/NR1H4/TARDBP/STXBP4/PRKCA/UCN3/RBP4/PSMD9/C1QTNF3/P2RY1/TACR2/GHRL/KISS1/APLN/CCKAR/PHPT1	133
BP	GO:0010522	regulation of calcium ion transport into cytosol	45/7096	102/18670	0.121	0.3104	0.2314	SLC8A1/FYN/PTPN6/LYN/DIAPH1/TMBIM6/CXCL9/CXCL11/P2RX7/CXCL10/PKD2/TGFB1/PTK2B/MYO5A/CORO1A/P2RY6/ABL1/GSTO1/PML/DMD/SRI/BCL2/BAX/PRKACA/CYBA/F2R/CAMK2D/CEMIP/CASQ1/CAPN3/CASQ2/HRC/BDKRB1/CD4/TMEM38B/LACRT/LIME1/SNCA/CX3CL1/P2RX2/BAK1/ATP1A2/ADCYAP1R1/NTSR1/P2RX5	45
BP	GO:0030148	sphingolipid biosynthetic process	45/7096	102/18670	0.121	0.3104	0.2314	ASAH1/ALDH3A2/SGMS2/CSNK1G2/CERS2/P2RX7/DEGS1/TNF/ELOVL5/CLN8/SGPL1/PRKCD/SGPP2/B4GALT6/CERS5/SPTLC2/SAMD8/VAPB/ELOVL7/CERS4/ORMDL2/SPHK1/P2RX1/ORMDL3/PRKD2/PPM1L/SGMS1/B4GALNT1/B4GALT5/UGCG/ST8SIA4/AGK/ST6GALNAC5/ACER3/PRKAA1/KDSR/PLA2G6/ST6GALNAC3/SMPD1/ST6GALNAC6/ELOVL6/SMPD2/ST8SIA1/ST3GAL5/DEGS2	45
BP	GO:0043491	protein kinase B signaling	112/7096	269/18670	0.121	0.3104	0.2314	KLF4/IGF1/FYN/CX3CR1/RAC2/PINK1/RNF41/PLEKHA1/BANK1/CD40/KITLG/CIB1/RRAS/ADAM8/TNF/AKR1C3/GAB1/PIK3R3/HCLS1/AXL/TGFB1/HGF/LEP/INSR/NRG1/HYAL2/RHOG/ARFGEF1/ITSN1/IGF1R/IL1B/CCL5/P2RY12/SIRT1/HLA-G/MFHAS1/RAC1/CHI3L1/IRS2/LCK/PDGFB/FGF1/PPP2R5C/FLCN/PTK2/MIR34A/SETX/HPSE/PLK3/TRAT1/INPP5K/PIK3CD/THEM4/OSM/TSPYL5/GRB2/INPP5F/PDGFA/ICOS/SEMA5A/BTN2A2/C1QBP/VAV1/EGFR/KLB/TXN/MUL1/IL18/CAV3/SPRY2/KL/CPNE1/MERTK/TCF7L2/OTUD3/RPS6KB2/RET/GCNT2/HBEGF/PKHD1/MAZ/HSP90AB1/PPP2R5B/PIK3CG/PHLPP2/F3/MTDH/GPX1/CD80/MTOR/MEIS3/TYRO3/RTN4/DAG1/CX3CL1/ITGB1BP1/IAPP/ENG/CCL19/MET/CCR7/SFRP5/FGF23/IL26/SESN2/ERBB3/RASD2/THPO/NTRK2/FGF6/PIK3CB/PTPRJ	112
BP	GO:0007274	neuromuscular synaptic transmission	15/7096	30/18670	0.1226	0.3132	0.2335	EGR3/STXBP1/ADARB1/FCHSD1/ETV5/CHRNG/CHRNA4/RAB3A/CHRNB2/DTNA/KIF1B/CHRNE/CHAT/P2RX2/FCHSD2	15
BP	GO:0051491	positive regulation of filopodium assembly	15/7096	30/18670	0.1226	0.3132	0.2335	DPYSL3/DNM3/ARAP1/SRF/NRP1/BCAS3/RHOQ/DOCK11/FSCN1/FMR1/TGFB3/MIEN1/CCR7/TENM2/ZMYND8	15
BP	GO:0061157	mRNA destabilization	15/7096	30/18670	0.1226	0.3132	0.2335	ZFP36/YTHDF3/MOV10/HNRNPR/METTL14/GIGYF2/METTL3/ZC3H12D/FTO/HNRNPD/CPEB3/ZFP36L2/ROCK2/PLEKHN1/UPF1	15
BP	GO:0033866	nucleoside bisphosphate biosynthetic process	31/7096	68/18670	0.1226	0.3132	0.2335	PDK4/CBR4/PANK2/ACOT7/PAPSS1/ACSL5/ELOVL5/PDK2/SCD/PANK3/PANK1/ACSL4/ACLY/GSTZ1/TECR/MPC2/ACACB/ELOVL7/MLYCD/ACSL6/PAPSS2/PDK1/PDHB/DLAT/PDP2/PDHA2/PDP1/SNCA/ELOVL6/PDPR/HSD17B12	31
BP	GO:0034030	ribonucleoside bisphosphate biosynthetic process	31/7096	68/18670	0.1226	0.3132	0.2335	PDK4/CBR4/PANK2/ACOT7/PAPSS1/ACSL5/ELOVL5/PDK2/SCD/PANK3/PANK1/ACSL4/ACLY/GSTZ1/TECR/MPC2/ACACB/ELOVL7/MLYCD/ACSL6/PAPSS2/PDK1/PDHB/DLAT/PDP2/PDHA2/PDP1/SNCA/ELOVL6/PDPR/HSD17B12	31
BP	GO:0034033	purine nucleoside bisphosphate biosynthetic process	31/7096	68/18670	0.1226	0.3132	0.2335	PDK4/CBR4/PANK2/ACOT7/PAPSS1/ACSL5/ELOVL5/PDK2/SCD/PANK3/PANK1/ACSL4/ACLY/GSTZ1/TECR/MPC2/ACACB/ELOVL7/MLYCD/ACSL6/PAPSS2/PDK1/PDHB/DLAT/PDP2/PDHA2/PDP1/SNCA/ELOVL6/PDPR/HSD17B12	31
BP	GO:0002714	positive regulation of B cell mediated immunity	18/7096	37/18670	0.1227	0.3132	0.2335	MAD2L2/STAT6/CD40/PTPRC/TNF/CD226/TGFB1/HLA-E/FCER2/MLH1/CLCF1/TFRC/TNFSF4/EXOSC3/TBX21/EXOSC6/PAXIP1/ATAD5	18
BP	GO:0002891	positive regulation of immunoglobulin mediated immune response	18/7096	37/18670	0.1227	0.3132	0.2335	MAD2L2/STAT6/CD40/PTPRC/TNF/CD226/TGFB1/HLA-E/FCER2/MLH1/CLCF1/TFRC/TNFSF4/EXOSC3/TBX21/EXOSC6/PAXIP1/ATAD5	18
BP	GO:0006623	protein targeting to vacuole	18/7096	37/18670	0.1227	0.3132	0.2335	NCOA4/LAMP2/VPS37B/VPS13A/M6PR/NAGPA/GNPTAB/VPS37C/CLU/GOSR2/VPS13D/NEDD4/HGS/VTI1A/AP3B1/VTI1B/AP3M1/SNX16	18
BP	GO:0006921	cellular component disassembly involved in execution phase of apoptosis	18/7096	37/18670	0.1227	0.3132	0.2335	AIFM1/DNASE2B/CASP3/NMNAT1/DFFA/DEDD2/HMGB1/IL6/DICER1/BAX/HMGB2/ST20/KPNA1/KPNB1/ENDOG/DNASE2/TOP2A/MIR146A	18
BP	GO:0032885	regulation of polysaccharide biosynthetic process	18/7096	37/18670	0.1227	0.3132	0.2335	IGF1/NFKB1/GSK3B/DYRK2/TGFB1/PPP1R3E/INSR/PPP1R3D/IRS2/PDGFB/INPP5K/PPP1R3B/PPP1R3F/AP2A1/PPP1CA/PPP1CB/ESRRB/MTOR	18
BP	GO:1903432	regulation of TORC1 signaling	18/7096	37/18670	0.1227	0.3132	0.2335	C9orf72/SEH1L/KLHL22/RRAGD/KPTN/FLCN/ATM/FNIP1/RRAGA/LAMTOR5/DYRK3/ITFG2/SESN1/TELO2/SMCR8/CLEC16A/DEPDC5/SESN2	18
BP	GO:0060688	regulation of morphogenesis of a branching structure	26/7096	56/18670	0.1232	0.3142	0.2342	WNT5A/LGR4/MAGED1/TNF/TGFB1/HGF/BCL11A/VEGFA/ABL1/PAX8/BMP7/ETV5/LRRK2/RXRA/BMP4/PDGFA/FKBPL/CAV3/SHOX2/HNF1B/MAP3K13/BTBD7/TACSTD2/WNT2B/RTN4/SMO	26
BP	GO:1903202	negative regulation of oxidative stress-induced cell death	26/7096	56/18670	0.1232	0.3142	0.2342	FYN/ATG7/PINK1/TSC1/PSAP/SLC7A11/ATF4/HGF/HIF1A/HSPB1/MAPK7/HTRA2/NCOA7/SIRT1/LRRK2/VNN1/FZD1/NFE2L2/TXN/WNT1/NR4A3/GPX1/PDE8A/BAG5/MET/OXR1	26
BP	GO:0014902	myotube differentiation	49/7096	112/18670	0.1239	0.3155	0.2352	IGF1/MYOF/SKI/CAPN2/SIK1/FLOT1/KLHL41/IL4R/CXCL9/CXCL10/CD53/PLEKHO1/DYRK1B/FLT3LG/RYR1/EHD1/HOMER1/SMYD3/NLN/MYH9/PTGFRN/MYOG/BCL2/ADAM12/CYP26B1/NFATC2/HDAC4/KLF5/KLHL40/MAMSTR/MMP14/LMOD3/CAV3/BIN3/WNT1/SHOX2/DNER/GPX1/MTOR/HDAC5/P2RX2/TMEM119/WNT10B/ACTA1/CACNA1H/SMO/KEL/MEF2C/MYF6	49
BP	GO:0098693	regulation of synaptic vesicle cycle	49/7096	112/18670	0.1239	0.3155	0.2352	APBA1/DNM3/RAP1B/SYT11/GSK3B/PLAA/PLD1/PPP3CB/STXBP1/UNC13B/GRIPAP1/FBXL20/CDK5/RAB3GAP1/DTNBP1/RAP1A/PREPL/LRRK2/CYFIP1/ADCY1/TOR1A/SH3GL1/DNM1/P2RX1/ADORA2B/VPS18/NAPA/RAB5A/CAMK2A/CHRM2/DNM1L/CHRNA4/ATP2A2/DVL1/FMR1/RAB3A/CHRNB2/P2RY4/SYT9/SYT1/RAB3B/VAMP1/SYT4/BRSK1/SNCA/RIMS2/WNT7A/NLGN2/P2RY1	49
BP	GO:1990748	cellular detoxification	49/7096	112/18670	0.1239	0.3155	0.2352	NQO1/S100A9/GCH1/ALOX5AP/SOD1/PTGS2/ADH5/MGST2/GSTP1/TNF/GSR/APOE/TXNRD1/GPX7/ESD/CD36/PRDX1/TXNDC17/AKR1A1/HBB/CAT/GSTO1/GSTZ1/GPX3/IPCEF1/GSTA1/BMP7/GPX4/GSTM3/RDH12/MGST1/PRDX6/HBQ1/AKR1B10/NFE2L2/DHFR/TXN/SESN1/MGST3/ATP7A/HP/GPX1/SRXN1/HBE1/MPO/NNT/SESN2/PTGS1/ALB	49
BP	GO:0051304	chromosome separation	40/7096	90/18670	0.1251	0.3155	0.2352	DUSP1/MAD2L2/DYNC1LI1/SPDL1/ERCC4/CSNK2A2/CENPE/KLHL22/CDK5RAP2/NSMCE2/SMARCAD1/CDC23/ESPL1/ZNF207/LCMT1/ATM/ANAPC5/NCAPD3/BUB3/NDC80/MLH1/RMI1/TOP2B/GEN1/M1AP/ZW10/MOS/CDC26/RIOK2/FANCM/DLGAP5/ANAPC4/DIS3L2/CDC27/CDC20/PCID2/RB1/ANAPC11/IK/TOP2A	40
BP	GO:0002024	diet induced thermogenesis	7/7096	12/18670	0.1253	0.3155	0.2352	APPL2/SCTR/ADRB1/OMA1/ADRB2/UCP1/TRPV4	7
BP	GO:0002921	negative regulation of humoral immune response	7/7096	12/18670	0.1253	0.3155	0.2352	PTPN6/CD55/A2M/CD59/SERPING1/CR1/VSIG4	7
BP	GO:0009086	methionine biosynthetic process	7/7096	12/18670	0.1253	0.3155	0.2352	ADI1/MTR/APIP/MTRR/ENOPH1/MTAP/BHMT	7
BP	GO:0010623	programmed cell death involved in cell development	7/7096	12/18670	0.1253	0.3155	0.2352	KITLG/IL1B/BCL2/BAX/CASP2/IL1A/CNTF	7
BP	GO:0032252	secretory granule localization	7/7096	12/18670	0.1253	0.3155	0.2352	MYO5A/RASGRP1/KIF1B/KIF5B/PIK3CG/KIF1C/TRIM46	7
BP	GO:0033523	histone H2B ubiquitination	7/7096	12/18670	0.1253	0.3155	0.2352	PAF1/UBE2E1/CDK9/DTX3L/LEO1/RNF20/CDC73	7
BP	GO:0033700	phospholipid efflux	7/7096	12/18670	0.1253	0.3155	0.2352	APOC1/APOE/ABCA1/APOA5/ABCG1/ABCA7/APOA1	7
BP	GO:0035437	maintenance of protein localization in endoplasmic reticulum	7/7096	12/18670	0.1253	0.3155	0.2352	HSPA5/GPAA1/KDELR3/KDELR2/INSIG1/RER1/OS9	7
BP	GO:0036005	response to macrophage colony-stimulating factor	7/7096	12/18670	0.1253	0.3155	0.2352	TLR2/PTPN2/TLR4/DOK1/FER/DCSTAMP/CSF1R	7
BP	GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	7/7096	12/18670	0.1253	0.3155	0.2352	TLR2/PTPN2/TLR4/DOK1/FER/DCSTAMP/CSF1R	7
BP	GO:0038110	interleukin-2-mediated signaling pathway	7/7096	12/18670	0.1253	0.3155	0.2352	IL2RG/PTPN2/PTK2B/IL2RB/STAT5A/SHC1/JAK1	7
BP	GO:0048302	regulation of isotype switching to IgG isotypes	7/7096	12/18670	0.1253	0.3155	0.2352	IL27RA/CD40/PTPRC/MLH1/TBX21/PAXIP1/ATAD5	7
BP	GO:0061450	trophoblast cell migration	7/7096	12/18670	0.1253	0.3155	0.2352	AGO2/ARHGDIB/ACVR1B/TIMP1/CALR/C1QBP/SYDE1	7
BP	GO:0070243	regulation of thymocyte apoptotic process	7/7096	12/18670	0.1253	0.3155	0.2352	WNT5A/ADAM8/HIF1A/NFKBID/BMP4/ADA/PTCRA	7
BP	GO:0070493	thrombin-activated receptor signaling pathway	7/7096	12/18670	0.1253	0.3155	0.2352	STMN1/IQGAP2/HPGD/PLEK/F2R/SNCA/MET	7
BP	GO:0070586	cell-cell adhesion involved in gastrulation	7/7096	12/18670	0.1253	0.3155	0.2352	KLF4/MYADM/MBP/MAPK7/IL1RN/APOA1/MAP2K5	7
BP	GO:0071107	response to parathyroid hormone	7/7096	12/18670	0.1253	0.3155	0.2352	HDAC4/PRKACA/ITGA2/FGF23/WNT10B/GJA1/MEF2C	7
BP	GO:0071712	ER-associated misfolded protein catabolic process	7/7096	12/18670	0.1253	0.3155	0.2352	SDF2L1/TOR1A/DERL1/POMT2/RNF185/RNF5/VCP	7
BP	GO:0090520	sphingolipid mediated signaling pathway	7/7096	12/18670	0.1253	0.3155	0.2352	EZR/S1PR4/S1PR3/S1PR1/SPHK1/GPR6/S1PR5	7
BP	GO:0099566	regulation of postsynaptic cytosolic calcium ion concentration	7/7096	12/18670	0.1253	0.3155	0.2352	SLC8A1/WNT5A/ITPR1/MYO5A/FZD9/SLC8A3/SYNPO	7
BP	GO:1900376	regulation of secondary metabolite biosynthetic process	7/7096	12/18670	0.1253	0.3155	0.2352	WNT5A/SLC7A11/ZEB2/RAPGEF2/ASIP/CDH3/APPL1	7
BP	GO:1900402	regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter	7/7096	12/18670	0.1253	0.3155	0.2352	KAT2B/NCOR1/FOXK2/PPARA/KAT2A/GCG/WDR5	7
BP	GO:1901163	regulation of trophoblast cell migration	7/7096	12/18670	0.1253	0.3155	0.2352	AGO2/ARHGDIB/ACVR1B/TIMP1/CALR/C1QBP/SYDE1	7
BP	GO:1902287	semaphorin-plexin signaling pathway involved in axon guidance	7/7096	12/18670	0.1253	0.3155	0.2352	PLXNB2/PLXNC1/PLXNA1/NRP1/PLXND1/PLXNA3/PLXNA2	7
BP	GO:1902916	positive regulation of protein polyubiquitination	7/7096	12/18670	0.1253	0.3155	0.2352	NOD2/BIRC2/SKP2/NMI/PTPN22/FBXO4/XIAP	7
BP	GO:1903894	regulation of IRE1-mediated unfolded protein response	7/7096	12/18670	0.1253	0.3155	0.2352	HSPA5/TMEM33/BCL2L11/BAX/DNAJB9/BFAR/BAK1	7
BP	GO:1905666	regulation of protein localization to endosome	7/7096	12/18670	0.1253	0.3155	0.2352	EZR/ABHD17C/RDX/DTX3L/MGAT3/MSN/ROCK2	7
BP	GO:2000344	positive regulation of acrosome reaction	7/7096	12/18670	0.1253	0.3155	0.2352	PLB1/CCDC87/FAM170B/HYAL3/PLCB1/CACNA1H/POMZP3	7
BP	GO:2001198	regulation of dendritic cell differentiation	7/7096	12/18670	0.1253	0.3155	0.2352	LILRB2/CEBPB/LILRB1/AGER/HMGB1/HLA-G/LGALS9	7
BP	GO:0032945	negative regulation of mononuclear cell proliferation	33/7096	73/18670	0.1259	0.3165	0.236	PTPN6/LILRB2/LYN/ARG2/GPNMB/MNDA/LST1/TNFRSF14/CEBPB/TNFRSF21/LILRB1/TGFB1/IL20RB/ZBTB7B/CASP3/IDO1/TYROBP/HLA-G/CTLA4/GLMN/ATM/VSIG4/SCGB1A1/PDCD1LG2/BMP4/CD300A/CD274/LGALS9/BTN2A2/TNFRSF13B/HAVCR2/CD80/TWSG1	33
BP	GO:0050672	negative regulation of lymphocyte proliferation	33/7096	73/18670	0.1259	0.3165	0.236	PTPN6/LILRB2/LYN/ARG2/GPNMB/MNDA/LST1/TNFRSF14/CEBPB/TNFRSF21/LILRB1/TGFB1/IL20RB/ZBTB7B/CASP3/IDO1/TYROBP/HLA-G/CTLA4/GLMN/ATM/VSIG4/SCGB1A1/PDCD1LG2/BMP4/CD300A/CD274/LGALS9/BTN2A2/TNFRSF13B/HAVCR2/CD80/TWSG1	33
BP	GO:1901983	regulation of protein acetylation	33/7096	73/18670	0.1259	0.3165	0.236	SPI1/GSK3B/TGFB1/SIN3A/ZNF451/ARRB1/RUVBL2/KAT7/SETD5/IL1B/SIRT1/PPARGC1A/FLCN/MIR34A/MUC1/HDAC2/KAT5/NOC2L/CTCF/ZMPSTE24/BRCA1/FAM161A/HINT2/KAT2A/PRKAA1/EID1/ARNTL/SET/SNCA/SOX4/PAXIP1/KLF15/TAF7	33
BP	GO:0006282	regulation of DNA repair	53/7096	122/18670	0.126	0.3169	0.2363	USP51/MAD2L2/PARP9/RAD51AP1/EYA3/CEBPG/UBE2N/SPIRE1/KLHL15/ERCC6/MAGEF1/ACTR2/PPP4C/PPP4R2/UIMC1/TMEM161A/DEK/RMI2/SETMAR/WRNIP1/PARG/UBR5/DHX9/PML/HMGB1/SMCHD1/NUDT16L1/SIRT1/CDK9/POLH/DTX3L/HDAC10/RAD52/PCNA/XRCC1/PARP3/FUS/USP1/TIMELESS/KDM4D/BRCA1/EGFR/RTEL1/EYA4/TEX15/BRCC3/AUNIP/MGMT/WAS/NUDT16/SPIDR/FIGNL1/ERCC8	53
BP	GO:0051651	maintenance of location in cell	42/7096	95/18670	0.127	0.3192	0.238	EZR/SUN2/PINK1/BARD1/TMSB10/APOE/SUPT7L/VPS13A/TWF2/TLN1/FTL/HSPA5/CDK5/SP100/PAFAH1B1/PML/CLMN/GPAA1/ASPM/SRI/BBS4/SYNE2/KDELR3/VPS13D/TLN2/KDELR2/SHANK1/FLNB/INSIG1/TXN/GPSM2/SCIN/SRGN/SPAG4/GAA/CD4/TOPORS/DAG1/RER1/ARL2BP/OS9/ALB	42
BP	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	23/7096	49/18670	0.1272	0.3195	0.2382	TNFAIP3/STAT1/NLRP12/GSTP1/TLE1/MAPKBP1/ABL1/NFKBID/CASP8/SIRT1/ASH1L/TNIP1/TNIP3/ZMYND11/RHOH/USP10/RIOK3/RORA/NLRX1/OPTN/RHOA/NR1H4/NLRC3	23
BP	GO:0097300	programmed necrotic cell death	23/7096	49/18670	0.1272	0.3195	0.2382	BIRC2/LY96/FAS/TNF/ALKBH7/TICAM1/TLR4/FZD9/CASP8/ARHGEF2/SPATA2/RBCK1/CYLD/BAX/BIRC3/MLKL/YBX3/MAP3K5/DNM1L/FADD/TRAF2/TLR3/PYGL	23
BP	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	28/7096	61/18670	0.1276	0.3202	0.2387	TRIM32/PTPN2/TNFAIP3/BIRC2/GSTP1/TNF/SPPL2A/IKBKG/CASP8/SPATA2/TRADD/RBCK1/CYLD/SPHK1/BIRC3/CASP1/RFFL/HIPK1/TRAF1/ADAM17/TRAF2/CASP4/CPNE1/TAX1BP1/APOA1/CLIP3/CHUK/NR1H4	28
BP	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	28/7096	61/18670	0.1276	0.3202	0.2387	S100A9/S100A8/BMF/SKIL/SOD1/PTPN2/PMAIP1/SIAH1/FBXW7/BCAP31/NUPR1/FIS1/MCL1/NCK1/SIRT1/SFPQ/LCK/FLCN/BCL2L11/SERINC3/NACC2/BCL2/BAX/DNM1L/BAD/BCLAF1/RAD9A/MSX1	28
BP	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	35/7096	78/18670	0.1287	0.3222	0.2402	CDKN1A/PMAIP1/MIF/CD44/SHISA5/FHIT/CD74/NUPR1/PDK2/DYRK2/PTTG1IP/HNRNPK/USP28/TMEM109/HINT1/PML/SIRT1/ELL3/WWOX/MUC1/AEN/MYBBP1A/BCL2/BAX/JMY/DDIT4/HIPK1/RRM2B/MDM2/TAF9B/PPP1R13B/MSX1/TOPORS/TRIAP1/ATAD5	35
BP	GO:2000300	regulation of synaptic vesicle exocytosis	35/7096	78/18670	0.1287	0.3222	0.2402	APBA1/RAP1B/GSK3B/STXBP1/UNC13B/FBXL20/CDK5/RAB3GAP1/DTNBP1/RAP1A/PREPL/LRRK2/ADCY1/P2RX1/ADORA2B/VPS18/NAPA/RAB5A/CAMK2A/CHRM2/DNM1L/CHRNA4/ATP2A2/DVL1/FMR1/RAB3A/CHRNB2/P2RY4/SYT9/SYT1/VAMP1/SYT4/RIMS2/WNT7A/P2RY1	35
BP	GO:0007030	Golgi organization	61/7096	142/18670	0.1289	0.3222	0.2402	ATP8B2/TANGO2/LMAN2L/MAP2K1/PLEKHM2/GOLGA8A/GOLGB1/CSNK1D/ARFGEF1/KIFC3/UBXN2B/GORASP2/DNAJC28/TMED10/NSFL1C/PDE4DIP/ATP8B1/RAB43/RAB33B/RAB29/LRRK2/STX5/CSNK1A1/PLK3/NPLOC4/ATL3/GOLPH3L/DNM2/VPS51/TBC1D20/GOLGA5/BCAS3/COG4/PI4K2A/STX16/MAP2K2/TJAP1/LMAN1/ARL1/VTI1A/ZW10/PRMT5/STX18/HACE1/TMED5/CLASP2/SEC23IP/TMED4/MAPK1/VRK1/COG2/COG1/EHD3/COG7/OPTN/TRAPPC8/BAG5/PDCD10/DYM/TRAPPC11/SEC16B	61
BP	GO:0038127	ERBB signaling pathway	61/7096	142/18670	0.1289	0.3222	0.2402	STAM/RHBDF2/RBPJ/PTPN2/ARAP1/NUP62/FBXW7/LGMN/GAB1/DUSP3/CDC37/TGFB1/DGKD/CBLB/SOCS5/ARF4/ZFYVE28/PTK2B/NRG1/ZGPAT/NCF1/ABL1/MVP/PTK6/SHC1/SHKBP1/PDE6G/PLAUR/RNF115/DOK1/PTK2/KIF16B/SNX6/MMP9/RNF126/TSG101/HGS/SH3TC2/GRB2/GRB7/FER/SPRY1/STUB1/VPS25/EGFR/ADAM17/SPRY2/PSEN1/MAPK1/SNX5/MATK/CPNE3/HBEGF/APP/RTN4/SHC3/SLC30A10/PRKCA/ERBB3/PTPRJ/RHBDF1	61
BP	GO:0006622	protein targeting to lysosome	11/7096	21/18670	0.1293	0.3222	0.2402	NCOA4/LAMP2/M6PR/NAGPA/GNPTAB/CLU/NEDD4/HGS/AP3B1/AP3M1/SNX16	11
BP	GO:0007035	vacuolar acidification	11/7096	21/18670	0.1293	0.3222	0.2402	ATP6V0D2/GRN/SLC11A1/DMXL1/TCIRG1/CLN3/ROGDI/ATP6V0E2/CLN6/CLN5/DMXL2	11
BP	GO:0017000	antibiotic biosynthetic process	11/7096	21/18670	0.1293	0.3222	0.2402	FYN/NANP/SOD1/STAT3/MPV17L/CYP1A2/CYBA/CYBB/MAOB/DUOXA1/CTNS	11
BP	GO:0031290	retinal ganglion cell axon guidance	11/7096	21/18670	0.1293	0.3222	0.2402	ALCAM/EPHB2/PTPRO/VEGFA/NRP1/SLIT2/RPL24/POU4F3/EPHB1/BMPR1B/PTPRM	11
BP	GO:0042438	melanin biosynthetic process	11/7096	21/18670	0.1293	0.3222	0.2402	WNT5A/SLC7A11/ZEB2/RAPGEF2/MYO5A/ASIP/DCT/CDH3/OCA2/APPL1/CTNS	11
BP	GO:0043984	histone H4-K16 acetylation	11/7096	21/18670	0.1293	0.3222	0.2402	MSL3/KAT8/SIRT1/MCRS1/PHF20/ZMPSTE24/BRCA1/KANSL1L/OGT/MSL1/WDR5	11
BP	GO:0046132	pyrimidine ribonucleoside biosynthetic process	11/7096	21/18670	0.1293	0.3222	0.2402	UPP1/CTPS2/CMPK1/NME3/NME4/NME1/UCK1/CTPS1/CAD/UCKL1/UPP2	11
BP	GO:0046827	positive regulation of protein export from nucleus	11/7096	21/18670	0.1293	0.3222	0.2402	GSK3B/SFN/EMD/IL1B/PRKACA/RIOK2/MDM2/TCF7L2/YWHAE/XPO4/CTDSPL2	11
BP	GO:0060972	left/right pattern formation	11/7096	21/18670	0.1293	0.3222	0.2402	DLL1/SETDB2/IFT172/IFT57/MEGF8/ARL13B/DPCD/CITED2/HSPB11/SNAI1/SMO	11
BP	GO:0070920	regulation of production of small RNA involved in gene silencing by RNA	11/7096	21/18670	0.1293	0.3222	0.2402	MAP2K1/TGFB1/BCDIN3D/NCOR1/TARBP2/BMP4/MAP2K2/ZMPSTE24/EGFR/ZC3H10/TERT	11
BP	GO:0072111	cell proliferation involved in kidney development	11/7096	21/18670	0.1293	0.3222	0.2402	STAT1/MYC/EGR1/BMP2/BMP7/PDGFB/FLCN/BMP4/WT1/PTCH1/PDGFD	11
BP	GO:1901739	regulation of myoblast fusion	11/7096	21/18670	0.1293	0.3222	0.2402	CAPN2/FLOT1/IL4R/CXCL9/CXCL10/CD53/FLT3LG/EHD1/MYOG/NFATC2/MYF6	11
BP	GO:1903392	negative regulation of adherens junction organization	11/7096	21/18670	0.1293	0.3222	0.2402	RDX/VEGFA/LRP1/ARHGAP6/BCAS3/MMP14/DMTN/CORO1C/CLASP2/RCC2/ITGB1BP1	11
BP	GO:1904886	beta-catenin destruction complex disassembly	11/7096	21/18670	0.1293	0.3222	0.2402	DVL2/GSK3B/FRAT2/FRAT1/CSNK1A1/FZD5/FZD1/PPP1CA/DVL1/WNT1/FZD2	11
BP	GO:2000678	negative regulation of transcription regulatory region DNA binding	11/7096	21/18670	0.1293	0.3222	0.2402	MAD2L2/FBXW7/PER2/SIN3A/ENHO/ZNF593/HEY1/SRI/HEY2/PSEN1/MSX1	11
BP	GO:0002639	positive regulation of immunoglobulin production	20/7096	42/18670	0.1307	0.3254	0.2426	MAD2L2/STAT6/CD40/IL4R/PTPRC/TGFB1/HLA-E/GPI/IL6/MLH1/CLCF1/TFRC/TNFSF4/TNFRSF4/EXOSC3/TBX21/EXOSC6/PAXIP1/ATAD5/RBP4	20
BP	GO:1903845	negative regulation of cellular response to transforming growth factor beta stimulus	37/7096	83/18670	0.1312	0.3265	0.2434	SKIL/SKI/FAM89B/SMAD7/SMAD2/PBLD/LDLRAD4/ZBTB7A/TGFB1/ZNF451/HSPA5/PMEPA1/CHST11/SIRT1/BCL9L/PEG10/SNX6/STRAP/DNM2/MTMR4/EID2/HTRA1/UBC/RASL11B/STUB1/ADAM17/WFIKKN1/WNT1/TGFB3/TGFB1I1/PIN1/SPINT3/LEMD3/GLG1/HTRA4/VEPH1/CD109	37
BP	GO:0021872	forebrain generation of neurons	30/7096	66/18670	0.1315	0.3269	0.2437	WNT5A/ATF5/METTL14/ZSWIM6/RAPGEF2/METTL3/SATB2/NUMB/ASPM/ARX/AKNA/DCLK2/NRP1/DISC1/NRP2/INHBA/UQCRQ/HES1/DCT/BCL11B/SLIT2/NUMBL/PLXNA3/ATP7A/NR2E1/CSF1R/RHOA/OTP/SHANK3/LHX6	30
BP	GO:1905710	positive regulation of membrane permeability	30/7096	66/18670	0.1315	0.3269	0.2437	BMF/SLC35F6/BLOC1S2/PMAIP1/YWHAH/SLC9A1/TMEM14A/GSK3B/MPV17L/FZD9/SFN/CASP8/RHOT2/CHCHD10/SLC25A5/BCL2L11/MAPK8/TMEM102/BCL2/BAX/GZMB/YWHAQ/MUL1/ACAA2/YWHAE/BAD/PPP1R13B/MOAP1/YWHAG/BAK1	30
BP	GO:0000280	nuclear division	166/7096	407/18670	0.1324	0.327	0.2438	IGF1/KLHDC8B/DUSP1/MAD2L2/WNT5A/NUP62/RAB11A/FLNA/DYNC1LI1/CCNB1IP1/RGCC/SPIRE1/SPDL1/RAN/ERCC4/ACTR2/LRP5/CHMP4B/SLC2A8/PSRC1/REC8/KIF3B/RAD1/TGFB1/MEI1/SYCP3/SMC5/UBE2S/SEH1L/PDS5A/INSR/CENPE/NAA10/UBXN2B/KLHL22/RAD51B/CDK5RAP2/CCDC155/SIRT7/IL1B/DSCC1/NSMCE2/TOM1L1/NSFL1C/CDKN1C/PHIP/KIF4A/PSMD13/SPAG5/TOM1L2/BMP7/MIS12/MOV10L1/KIF2A/CTDP1/PDGFB/CDC23/RCC1/ESPL1/ASPM/ZNF207/CENPC/LCMT1/SMC2/ATM/ANAPC5/CHAMP1/NCAPD3/BUB3/SPHK1/PHF23/AKAP8/SPICE1/BCCIP/USP16/CCNE1/NDC80/MLH1/DNMT3L/PPP2R2D/BMP4/CHMP2A/CYP26B1/CDKN1B/KIF20B/MAD2L1BP/RMI1/TOP2B/RAD54B/DSN1/IL1A/NDEL1/NUF2/GEN1/M1AP/NUSAP1/MND1/INCENP/ZW10/CHMP1A/VPS4B/UBE2C/PRMT5/CENPK/ACTR3/CALR/MOS/TUBG2/NFE2L1/CDC26/PLCB1/CLASP2/STAG3/SYCE3/RIOK2/CCNA1/FANCM/DLGAP5/KIF2C/BRDT/SMC3/KATNB1/RPL24/ANAPC4/MTBP/DIS3L2/RNF212B/MKI67/CDC27/CDC20/FANCD2/MASTL/PIN1/PCID2/RB1/STAG1/TEX15/MSX1/DPEP3/PSMC3IP/CUL9/MISP/ANKRD31/AURKAIP1/RHOA/AURKA/ANAPC11/FANCA/IK/KPNB1/MSTO1/CHMP1B/UBE2B/CNTD1/CCDC8/RRS1/CEP85/KIF14/BOD1/HORMAD1/AAAS/PRC1/TOP2A/WRAP73/FIGNL1/L3MBTL1	166
BP	GO:0006636	unsaturated fatty acid biosynthetic process	25/7096	54/18670	0.1326	0.327	0.2438	ALOX5/ANXA1/ALOX5AP/PTGS2/MIF/DEGS1/CD74/ELOVL5/AKR1C3/SCD/HPGD/FADS3/IL1B/ELOVL7/SIRT1/DECR2/PNPLA8/PTGES3/ALOX15B/HPGDS/FABP5/ELOVL6/ABCD1/FADS2/PTGS1	25
BP	GO:0009066	aspartate family amino acid metabolic process	25/7096	54/18670	0.1326	0.327	0.2438	SMS/ASRGL1/ADI1/AHCY/MTR/ALDH7A1/PHYKPL/APIP/MTRR/ENOPH1/OGDH/ASNSD1/PLOD1/MTAP/ASNS/BHMT/PLOD2/GOT2/AHCYL2/AHCYL1/AASDHPPT/HYKK/PHGDH/MAT1A/PIPOX	25
BP	GO:0035384	thioester biosynthetic process	25/7096	54/18670	0.1326	0.327	0.2438	PDK4/CBR4/ACSL5/ELOVL5/PDK2/SCD/ACSL4/ACLY/GSTZ1/TECR/MPC2/ACACB/ELOVL7/MLYCD/ACSL6/PDK1/PDHB/DLAT/PDP2/PDHA2/PDP1/SNCA/ELOVL6/PDPR/HSD17B12	25
BP	GO:0071616	acyl-CoA biosynthetic process	25/7096	54/18670	0.1326	0.327	0.2438	PDK4/CBR4/ACSL5/ELOVL5/PDK2/SCD/ACSL4/ACLY/GSTZ1/TECR/MPC2/ACACB/ELOVL7/MLYCD/ACSL6/PDK1/PDHB/DLAT/PDP2/PDHA2/PDP1/SNCA/ELOVL6/PDPR/HSD17B12	25
BP	GO:0000266	mitochondrial fission	17/7096	35/18670	0.1331	0.327	0.2438	PINK1/TMEM135/GDAP1/MX2/MIEF1/FIS1/DDHD1/LRRK2/PPARGC1A/MTFR1L/SLC25A46/MX1/DNM1L/MUL1/INF2/MTFR2/MTFP1	17
BP	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic	17/7096	35/18670	0.1331	0.327	0.2438	LSM5/DCP1B/DCP2/LSM7/DCPS/EXOSC2/EDC4/EXOSC7/TTC37/CNOT7/DIS3L2/EXOSC9/EXOSC3/EXOSC6/SKIV2L/EXOSC8/EXOSC5	17
BP	GO:0002701	negative regulation of production of molecular mediator of immune response	17/7096	35/18670	0.1331	0.327	0.2438	TMBIM6/BCL6/SMAD7/HFE/TNF/IRAK3/HMOX1/LILRB1/CD22/TGFB1/HLA-F/CD96/PARP3/IL13RA2/APOA1/TGFB3/TBX21	17
BP	GO:0015695	organic cation transport	17/7096	35/18670	0.1331	0.327	0.2438	SLC47A1/SLC22A4/SLC25A19/SLC22A18/SLC25A20/SLC22A5/OAZ3/SEC14L1/SLC7A8/SLC25A47/PSEN1/RALBP1/SLC44A2/SLC25A45/AZIN2/SLC22A16/TACR2	17
BP	GO:0019076	viral release from host cell	17/7096	35/18670	0.1331	0.327	0.2438	TRIM32/TRIM13/VPS37B/CHMP4B/TRIM26/DDB1/PML/TRIM11/TRIM21/CHMP2A/TSG101/IST1/VPS4B/MID2/SMC3/TRIM15/PC	17
BP	GO:0032689	negative regulation of interferon-gamma production	17/7096	35/18670	0.1331	0.327	0.2438	LILRB1/AXL/IL20RB/TLR4/HMGB1/SCGB1A1/PDCD1LG2/CD96/INHBA/CD274/LGALS9/PGLYRP4/C1QBP/TNFSF4/HAVCR2/INHA/NR1H4	17
BP	GO:0035890	exit from host	17/7096	35/18670	0.1331	0.327	0.2438	TRIM32/TRIM13/VPS37B/CHMP4B/TRIM26/DDB1/PML/TRIM11/TRIM21/CHMP2A/TSG101/IST1/VPS4B/MID2/SMC3/TRIM15/PC	17
BP	GO:0035891	exit from host cell	17/7096	35/18670	0.1331	0.327	0.2438	TRIM32/TRIM13/VPS37B/CHMP4B/TRIM26/DDB1/PML/TRIM11/TRIM21/CHMP2A/TSG101/IST1/VPS4B/MID2/SMC3/TRIM15/PC	17
BP	GO:0052126	movement in host environment	17/7096	35/18670	0.1331	0.327	0.2438	TRIM32/TRIM13/VPS37B/CHMP4B/TRIM26/DDB1/PML/TRIM11/TRIM21/CHMP2A/TSG101/IST1/VPS4B/MID2/SMC3/TRIM15/PC	17
BP	GO:0052192	movement in environment of other organism involved in symbiotic interaction	17/7096	35/18670	0.1331	0.327	0.2438	TRIM32/TRIM13/VPS37B/CHMP4B/TRIM26/DDB1/PML/TRIM11/TRIM21/CHMP2A/TSG101/IST1/VPS4B/MID2/SMC3/TRIM15/PC	17
BP	GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway	17/7096	35/18670	0.1331	0.327	0.2438	NOD2/TNFAIP3/BIRC2/UBE2N/NFKBIA/RELA/TAB3/TRAF6/IKBKG/TLR4/PTPN22/CASP8/CYLD/TAB1/BIRC3/UBC/XIAP	17
BP	GO:0098751	bone cell development	17/7096	35/18670	0.1331	0.327	0.2438	SIGLEC15/PTPN6/NOTCH2/ATP6AP1/FBXW7/LILRB1/SRF/PAFAH1B1/TYROBP/TAL1/ANXA2P2/CLDN18/MEIS1/ANXA2/FOXP1/SLC9B2/THPO	17
BP	GO:0006760	folic acid-containing compound metabolic process	14/7096	28/18670	0.1333	0.327	0.2438	GCH1/MTHFD2/FOLR2/MTRR/SHMT2/ATIC/SLC46A1/TYMS/SHMT1/DHFR/FPGS/ALDH1L1/SLC25A32/PIPOX	14
BP	GO:0009074	aromatic amino acid family catabolic process	14/7096	28/18670	0.1333	0.327	0.2438	ASRGL1/IL4I1/PCBD1/HAL/HNMT/FAH/IDO1/GSTZ1/QDPR/KYNU/HAAO/IDO2/AMDHD1/TDO2	14
BP	GO:0031440	regulation of mRNA 3'-end processing	14/7096	28/18670	0.1333	0.327	0.2438	BARD1/ZC3H14/PAF1/CDK9/PAPOLA/SNRPA/CPEB1/CPEB3/LEO1/RNF20/AHCYL1/CCNT1/CDC73/CPSF7	14
BP	GO:0045577	regulation of B cell differentiation	14/7096	28/18670	0.1333	0.327	0.2438	PTPN6/IL7/CYLD/ID2/PPP2R3C/INHBA/MMP14/NFAM1/BAD/ZFP36L2/PCID2/INHA/IKZF3/SLAMF8	14
BP	GO:0090383	phagosome acidification	14/7096	28/18670	0.1333	0.327	0.2438	ATP6V0D2/ATP6V1C1/ATP6V0C/TCIRG1/ATP6V1A/RAB20/ATP6V1G3/ATP6V1B2/RAB38/ATP6V1D/ATP6V0E2/ATP6V1G2/ATP6V1B1/SLAMF8	14
BP	GO:1902745	positive regulation of lamellipodium organization	14/7096	28/18670	0.1333	0.327	0.2438	RAC2/ENPP2/TWF2/RAC1/CORO1B/DNM2/HDAC4/CORO1C/FSCN1/WNT1/ATP7A/ARPC2/MTOR/NCKAP1	14
BP	GO:1902932	positive regulation of alcohol biosynthetic process	14/7096	28/18670	0.1333	0.327	0.2438	POR/TNF/PTAFR/P2RY6/IL1B/FGF1/ABCG1/PRKAA1/IFNG/SNCA/CD244/ADCYAP1R1/P2RY1/NTSR1	14
BP	GO:0042147	retrograde transport, endosome to Golgi	39/7096	88/18670	0.1333	0.327	0.2438	RAB9A/SNX1/DENND5A/HEATR5A/TBC1D5/TMEM87A/VAMP3/RAB29/PREPL/GOSR2/LRRK2/GOSR1/CLTCL1/STX5/SNX6/TBC1D17/VPS51/RNF126/TMEM87B/STX16/VPS52/ARL1/VTI1A/CLN5/ARFRP1/RAB7B/YKT6/VPS29/SNX5/VTI1B/RHOBTB3/EVI5/TBC1D10C/EHD3/VPS26B/DENND2A/RGP1/TBC1D10B/SNX32	39
BP	GO:0070125	mitochondrial translational elongation	39/7096	88/18670	0.1333	0.327	0.2438	MRPS6/MRPL35/MRPL45/CHCHD1/MRPL40/MRPS30/MRPL34/MRPS16/MRPS14/MRPL54/MRPL44/MRPL33/MRPL51/OXA1L/MRPL49/MRPL3/MRPL42/DAP3/MRPS34/MRPL4/GADD45GIP1/MRPS33/MRPL20/MRPL46/MRPS18B/MRPL24/MRPL36/MRPS25/MRPS15/MRPL48/AURKAIP1/MRPL41/MRPL2/GFM1/MRPS2/MRPS9/MRPL30/MRPL1/MRPS17	39
BP	GO:0060560	developmental growth involved in morphogenesis	98/7096	235/18670	0.1345	0.327	0.2438	RTN4R/FN1/DPYSL2/WNT5A/C9orf72/SEMA4B/SPP1/RAB11A/S1PR1/ULK2/RDH10/LAMB2/ALCAM/VCL/IFRD1/APOE/GSK3B/ZEB2/PLAA/CXCL12/TWF2/TGFB1/PPP3CB/SIN3A/PAK1/MEGF8/BCL11A/SRF/SEMA4A/ITGA4/VEGFA/USP9X/CDK5/TNFRSF12A/CYFIP2/ABL1/PAFAH1B1/GDI1/SEMA4C/SEMA4D/LRP1/DCC/MESP1/FGF1/CYFIP1/SEMA6B/PLXNA1/NRP1/DISC1/SEMA3B/DNM2/BMP4/L1CAM/NRP2/LPAR3/IST1/NDEL1/OLFM1/KDM5B/WDR36/SEMA5A/FSTL4/SPRY1/IMPACT/ULK1/MUL1/BIN3/ITSN2/SLIT2/SPRY2/DVL1/CPNE1/SEMA5B/POU4F3/RASAL1/HNF1B/MAP3K13/RUFY3/PLXNA3/SYT1/CPNE9/HSP90AB1/SYT2/EIF2AK4/SYT4/PRKCZ/AURKA/APP/RTN4/CRABP2/RIMS2/FGF13/MACF1/TRPV2/TRIM46/BMPR2/FMN1/SLIT3	98
BP	GO:0001768	establishment of T cell polarity	6/7096	10/18670	0.1348	0.327	0.2438	DOCK8/FLOT2/MYH9/CYP26B1/CCL19/CCR7	6
BP	GO:0006222	UMP biosynthetic process	6/7096	10/18670	0.1348	0.327	0.2438	UPP1/CMPK1/UCK1/CAD/UCKL1/UPP2	6
BP	GO:0006930	substrate-dependent cell migration, cell extension	6/7096	10/18670	0.1348	0.327	0.2438	NCK1/OPHN1/SDCBP/P2RY12/NRP1/CD2AP	6
BP	GO:0007016	cytoskeletal anchoring at plasma membrane	6/7096	10/18670	0.1348	0.327	0.2438	EZR/TLN1/TLN2/SHANK1/FLNB/DAG1	6
BP	GO:0009173	pyrimidine ribonucleoside monophosphate metabolic process	6/7096	10/18670	0.1348	0.327	0.2438	UPP1/CMPK1/UCK1/CAD/UCKL1/UPP2	6
BP	GO:0009174	pyrimidine ribonucleoside monophosphate biosynthetic process	6/7096	10/18670	0.1348	0.327	0.2438	UPP1/CMPK1/UCK1/CAD/UCKL1/UPP2	6
BP	GO:0014041	regulation of neuron maturation	6/7096	10/18670	0.1348	0.327	0.2438	BCL11A/LRRK2/BCL2/MAP3K13/RET/MTOR	6
BP	GO:0016102	diterpenoid biosynthetic process	6/7096	10/18670	0.1348	0.327	0.2438	RBP1/RDH10/AKR1C3/DHRS9/ALDH8A1/CRABP2	6
BP	GO:0021562	vestibulocochlear nerve development	6/7096	10/18670	0.1348	0.327	0.2438	ATP8B1/TIFAB/NRP1/NRP2/CHRNB2/POU4F3	6
BP	GO:0031848	protection from non-homologous end joining at telomere	6/7096	10/18670	0.1348	0.327	0.2438	ERCC4/XRCC1/ERCC1/DCLRE1A/ACD/DCLRE1C	6
BP	GO:0032836	glomerular basement membrane development	6/7096	10/18670	0.1348	0.327	0.2438	LAMB2/MPV17/SULF2/COL4A3/NID1/WT1	6
BP	GO:0033314	mitotic DNA replication checkpoint	6/7096	10/18670	0.1348	0.327	0.2438	HUS1B/ZNF830/RAD17/TICRR/CLSPN/TOPBP1	6
BP	GO:0034454	microtubule anchoring at centrosome	6/7096	10/18670	0.1348	0.327	0.2438	NINL/PCM1/BBS4/HOOK3/CCDC120/CEP19	6
BP	GO:0035520	monoubiquitinated protein deubiquitination	6/7096	10/18670	0.1348	0.327	0.2438	USP16/USP1/ATXN3/USP7/BAP1/ATXN3L	6
BP	GO:0039530	MDA-5 signaling pathway	6/7096	10/18670	0.1348	0.327	0.2438	IRF7/DDX60/IFIH1/ANKRD17/C1QBP/RIOK3	6
BP	GO:0044351	macropinocytosis	6/7096	10/18670	0.1348	0.327	0.2438	APPL2/MAPKAPK3/SNX33/DNM2/MAPKAPK2/APPL1	6
BP	GO:0046049	UMP metabolic process	6/7096	10/18670	0.1348	0.327	0.2438	UPP1/CMPK1/UCK1/CAD/UCKL1/UPP2	6
BP	GO:0046642	negative regulation of alpha-beta T cell proliferation	6/7096	10/18670	0.1348	0.327	0.2438	ARG2/TNFRSF14/ZBTB7B/CD274/LGALS9/TWSG1	6
BP	GO:0048304	positive regulation of isotype switching to IgG isotypes	6/7096	10/18670	0.1348	0.327	0.2438	CD40/PTPRC/MLH1/TBX21/PAXIP1/ATAD5	6
BP	GO:0051014	actin filament severing	6/7096	10/18670	0.1348	0.327	0.2438	FMNL1/GMFG/MYH9/SRGAP2/SCIN/FLII	6
BP	GO:0051133	regulation of NK T cell activation	6/7096	10/18670	0.1348	0.327	0.2438	ZBTB7B/RASAL3/CD300A/IL18/IL12B/IL23A	6
BP	GO:0051409	response to nitrosative stress	6/7096	10/18670	0.1348	0.327	0.2438	DUSP6/GCLM/ADH5/GCLC/ATM/DNAJA1	6
BP	GO:0070099	regulation of chemokine-mediated signaling pathway	6/7096	10/18670	0.1348	0.327	0.2438	HIF1A/CCL5/RNF113A/SLIT2/TREM2/SLIT3	6
BP	GO:0071233	cellular response to leucine	6/7096	10/18670	0.1348	0.327	0.2438	KLHL22/RRAGD/SESN1/UBR1/MTOR/SESN2	6
BP	GO:0071609	chemokine (C-C motif) ligand 5 production	6/7096	10/18670	0.1348	0.327	0.2438	ARG2/MAVS/DDX3X/MCOLN2/MUL1/TRPV4	6
BP	GO:0072124	regulation of glomerular mesangial cell proliferation	6/7096	10/18670	0.1348	0.327	0.2438	EGR1/BMP7/PDGFB/BMP4/WT1/PDGFD	6
BP	GO:0072203	cell proliferation involved in metanephros development	6/7096	10/18670	0.1348	0.327	0.2438	STAT1/MYC/EGR1/BMP7/WT1/PTCH1	6
BP	GO:0090336	positive regulation of brown fat cell differentiation	6/7096	10/18670	0.1348	0.327	0.2438	METRNL/FNDC5/PTGS2/NAPEPLD/ZBTB7B/VSTM2A	6
BP	GO:1902033	regulation of hematopoietic stem cell proliferation	6/7096	10/18670	0.1348	0.327	0.2438	PIM1/KITLG/N4BP2L2/EIF2AK2/ATXN1L/THPO	6
BP	GO:1902237	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	6/7096	10/18670	0.1348	0.327	0.2438	PTPN2/PMAIP1/NCK1/SIRT1/BCL2L11/SERINC3	6
BP	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway	6/7096	10/18670	0.1348	0.327	0.2438	TRIM32/CASP1/ADAM17/TRAF2/CASP4/CPNE1	6
BP	GO:1903897	regulation of PERK-mediated unfolded protein response	6/7096	10/18670	0.1348	0.327	0.2438	PTPN2/PPP1R15A/HSPA5/NCK1/TMEM33/PPP1R15B	6
BP	GO:1904526	regulation of microtubule binding	6/7096	10/18670	0.1348	0.327	0.2438	PPP2CA/ABL1/MAPRE1/MARK2/TTBK2/GAS8	6
BP	GO:1904896	ESCRT complex disassembly	6/7096	10/18670	0.1348	0.327	0.2438	VTA1/CHMP2A/IST1/CHMP1A/VPS4B/CHMP1B	6
BP	GO:1904903	ESCRT III complex disassembly	6/7096	10/18670	0.1348	0.327	0.2438	VTA1/CHMP2A/IST1/CHMP1A/VPS4B/CHMP1B	6
BP	GO:1990253	cellular response to leucine starvation	6/7096	10/18670	0.1348	0.327	0.2438	RRAGD/IMPACT/SESN1/EIF2AK4/MTOR/SESN2	6
BP	GO:2000035	regulation of stem cell division	6/7096	10/18670	0.1348	0.327	0.2438	NCOA3/CDK2AP2/EVI2B/ESRRB/PRDM15/LBH	6
BP	GO:2000109	regulation of macrophage apoptotic process	6/7096	10/18670	0.1348	0.327	0.2438	NOD2/IRF7/CCL5/SIRT1/CCR5/MEF2C	6
BP	GO:2000644	regulation of receptor catabolic process	6/7096	10/18670	0.1348	0.327	0.2438	APOE/FURIN/DTX3L/MTMR2/ANXA2P2/ANXA2	6
BP	GO:1901184	regulation of ERBB signaling pathway	41/7096	93/18670	0.1352	0.3278	0.2444	STAM/RHBDF2/RBPJ/PTPN2/ARAP1/NUP62/FBXW7/LGMN/DUSP3/CBLB/SOCS5/ZFYVE28/ZGPAT/NCF1/PTK6/SHC1/SHKBP1/PDE6G/PLAUR/RNF115/DOK1/SNX6/MMP9/RNF126/TSG101/HGS/SH3TC2/GRB2/FER/SPRY1/VPS25/EGFR/ADAM17/SPRY2/PSEN1/SNX5/HBEGF/APP/RTN4/PTPRJ/RHBDF1	41
BP	GO:0033865	nucleoside bisphosphate metabolic process	60/7096	140/18670	0.1361	0.3296	0.2457	ACOT13/PDK4/CBR4/FAR2/HMGCL/PANK2/ACOT7/PAPSS1/ACSL5/ACSM5/IMPAD1/ELOVL5/HMGCR/PDK2/HDDC3/HMGCS1/ACOT9/SULT1C2/SCD/OXSM/PANK3/PANK1/ACSL4/ACLY/TPST2/GSTZ1/MCEE/TECR/HSD17B4/MPC2/ACACB/OGDH/ELOVL7/DGAT2/MLYCD/KYNU/ACSL6/PAPSS2/THEM4/PDK1/ABHD14B/PDHB/FAR1/SUCLG2/DLAT/PDP2/NUDT7/DBI/PDHA2/PDP1/SULT1B1/CROT/SNCA/ELOVL6/ABCD1/PDPR/TDO2/HSD17B12/ACOT8/PIPOX	60
BP	GO:0033875	ribonucleoside bisphosphate metabolic process	60/7096	140/18670	0.1361	0.3296	0.2457	ACOT13/PDK4/CBR4/FAR2/HMGCL/PANK2/ACOT7/PAPSS1/ACSL5/ACSM5/IMPAD1/ELOVL5/HMGCR/PDK2/HDDC3/HMGCS1/ACOT9/SULT1C2/SCD/OXSM/PANK3/PANK1/ACSL4/ACLY/TPST2/GSTZ1/MCEE/TECR/HSD17B4/MPC2/ACACB/OGDH/ELOVL7/DGAT2/MLYCD/KYNU/ACSL6/PAPSS2/THEM4/PDK1/ABHD14B/PDHB/FAR1/SUCLG2/DLAT/PDP2/NUDT7/DBI/PDHA2/PDP1/SULT1B1/CROT/SNCA/ELOVL6/ABCD1/PDPR/TDO2/HSD17B12/ACOT8/PIPOX	60
BP	GO:0034032	purine nucleoside bisphosphate metabolic process	60/7096	140/18670	0.1361	0.3296	0.2457	ACOT13/PDK4/CBR4/FAR2/HMGCL/PANK2/ACOT7/PAPSS1/ACSL5/ACSM5/IMPAD1/ELOVL5/HMGCR/PDK2/HDDC3/HMGCS1/ACOT9/SULT1C2/SCD/OXSM/PANK3/PANK1/ACSL4/ACLY/TPST2/GSTZ1/MCEE/TECR/HSD17B4/MPC2/ACACB/OGDH/ELOVL7/DGAT2/MLYCD/KYNU/ACSL6/PAPSS2/THEM4/PDK1/ABHD14B/PDHB/FAR1/SUCLG2/DLAT/PDP2/NUDT7/DBI/PDHA2/PDP1/SULT1B1/CROT/SNCA/ELOVL6/ABCD1/PDPR/TDO2/HSD17B12/ACOT8/PIPOX	60
BP	GO:0031102	neuron projection regeneration	27/7096	59/18670	0.1371	0.3314	0.2471	KLF4/RTN4R/GRN/LRIG2/SPP1/MAP2K1/MTR/LAMB2/JAK2/CERS2/NREP/HGF/CTNNA1/LRP1/BCL2/NDEL1/INPP5F/RTN4RL1/CNTF/ULK1/DHFR/JAM3/APOA1/RTN4RL2/MAP4K4/DAG1/KREMEN1	27
BP	GO:1902883	negative regulation of response to oxidative stress	27/7096	59/18670	0.1371	0.3314	0.2471	FYN/ATG7/PINK1/TSC1/PSAP/SLC7A11/ATF4/HGF/HIF1A/HSPB1/MAPK7/HTRA2/NCOA7/SIRT1/LRRK2/VNN1/FZD1/NFE2L2/TXN/GGT7/WNT1/NR4A3/GPX1/PDE8A/BAG5/MET/OXR1	27
BP	GO:0010799	regulation of peptidyl-threonine phosphorylation	22/7096	47/18670	0.1373	0.3314	0.2471	WNT5A/AZU1/SMAD7/UBE2K/TGFB1/BMP7/CHI3L1/TNKS1BP1/SPHK1/PRKAG2/INPP5K/DDIT4/DMTN/SPRED1/CEMIP/SPRY2/MAPK1/EIF4G1/PPEF2/TRIM6/APP/GCG	22
BP	GO:0018198	peptidyl-cysteine modification	22/7096	47/18670	0.1373	0.3314	0.2471	S100A9/S100A8/ATP2B4/ZDHHC20/GAPDH/ADH5/ZDHHC9/NCOA7/ZDHHC6/DMD/MOCS3/ZDHHC14/ZDHHC2/ZDHHC18/TMX3/RAB3B/SNTA1/RAB3D/CLIP3/ZDHHC12/ZDHHC21/OXR1	22
BP	GO:0042551	neuron maturation	22/7096	47/18670	0.1373	0.3314	0.2471	NR4A2/KCNIP2/BCL11A/B4GALT6/CDKN1C/LRRK2/EPHA8/BCL2/LGI4/B4GALT5/CLN5/C1QL1/MAP3K13/RET/RB1/MTOR/PICK1/APP/SRRM4/CX3CL1/IRX5/GLDN	22
BP	GO:0051181	cofactor transport	22/7096	47/18670	0.1373	0.3314	0.2471	SLC48A1/SLC19A2/FLVCR2/SLC23A2/SLC25A19/SLC33A1/SLC25A20/FOLR2/P2RX7/SLC7A11/CD320/ABCB6/SLC46A1/SLC5A6/LMBRD1/SLC25A47/SLC25A26/TCN1/HRG/SLC25A45/SLC25A32/ABCB7	22
BP	GO:0070169	positive regulation of biomineral tissue development	22/7096	47/18670	0.1373	0.3314	0.2471	SLC8A1/ACVR2B/ATRAID/CEBPB/P2RX7/ATF4/TGFB1/FZD9/BMP2/ISG15/BMP7/BMPR1A/BMP4/ADRB2/KL/TGFB3/WNT6/TMEM119/WNT10B/BMPR1B/MEF2C/BMPR2	22
BP	GO:0120163	negative regulation of cold-induced thermogenesis	22/7096	47/18670	0.1373	0.3314	0.2471	ACOT13/ACVR2B/RBPJ/ALDH1A1/ABHD6/LGR4/IL15/ATF4/ARRDC3/IL18R1/IP6K1/NR1H2/TLR4/TFE3/FLCN/PLCL1/NR1H3/ADAM17/PLCL2/ARNTL/RB1/WNT10B	22
BP	GO:1900744	regulation of p38MAPK cascade	22/7096	47/18670	0.1373	0.3314	0.2471	EZR/DUSP1/DUSP10/MAP3K4/GADD45B/HGF/LEP/NCF1/PTPN22/BMP2/VEGFA/IL1B/AGER/MFHAS1/CYLD/RELL2/SPHK1/MAP3K5/CAV3/ULK4/PRMT1/SASH1	22
BP	GO:0030500	regulation of bone mineralization	34/7096	76/18670	0.1376	0.332	0.2475	SLC8A1/ACVR2B/S1PR1/ATRAID/P2RX7/TGFB1/HIF1A/PTK2B/FZD9/BMP2/LTBP3/ISG15/TRPM4/BMP7/BCOR/BMPR1A/BMP4/ADRB2/ZMPSTE24/KL/SRGN/CYP27B1/TGFB3/BMP2K/MGP/NBR1/TMEM119/FGF23/WNT10B/GJA1/GREM1/BMPR1B/MEF2C/BMPR2	34
BP	GO:0032091	negative regulation of protein binding	45/7096	103/18670	0.1382	0.3333	0.2485	STMN1/TMBIM6/HFE/GSK3B/TMC8/ACTB/LRPAP1/PRKCD/ADAM15/RUVBL2/ITGA4/HSPA5/CTSZ/IFIT2/DTNBP1/SYMPK/EIF2S1/GPSM1/TTBK1/PDGFB/LRRK2/TDG/CSNK1E/MAPK8/DISC1/BAX/ADRB2/GTF2F1/IFIT1/STUB1/PPP1CA/PEX14/PPARA/BAG2/DVL1/EFHB/GNL3L/PIN1/CARM1/AURKA/PIM2/ITGB1BP1/TTBK2/MET/CFHR5	45
BP	GO:0048259	regulation of receptor-mediated endocytosis	45/7096	103/18670	0.1382	0.3333	0.2485	ARF6/SYT11/FLOT1/APOC1/HFE/TBC1D5/ARRB1/LRPAP1/CD63/HNRNPK/USP46/VEGFA/OPHN1/NUMB/PLCG2/SDCBP/SFRP4/CLU/RAC1/ATXN2/ARC/APOA5/BICD1/ARF1/DNAJC6/UBQLN2/DNM2/SERPINE1/MTMR2/RABGEF1/CD2AP/AP2A1/ANXA2P2/FMR1/MKLN1/ANKRD13D/ANXA2/PICK1/CCL19/GSG1L/PICALM/ATAD1/GREM1/PIK3CB/APLN	45
BP	GO:0006302	double-strand break repair	103/7096	248/18670	0.1391	0.3351	0.2498	USP51/ZFYVE26/MAD2L2/PARP9/BARD1/RAD51AP1/TDP2/EYA3/MCM6/CIB1/MCM2/HUS1B/NABP1/UBE2N/SPIRE1/KLHL15/ERCC4/MAGEF1/ACTR2/PPP4C/PPP4R2/REC8/ZBTB7A/SMC5/RNF138/RPA1/UIMC1/DEK/PARP2/RMI2/SETMAR/KDM2A/RAD51B/CCDC155/APTX/PALB2/HERC2/NSMCE2/XRCC5/SAMHD1/UBR5/PML/SMCHD1/NUDT16L1/SMARCAD1/SFPQ/AP5S1/SUMO1/ATM/TNKS1BP1/SETX/XRCC4/DTX3L/ACTR5/KAT5/RAD52/MLH1/XRCC1/PARP3/ERCC1/FUS/RFWD3/YY1/RMI1/RAD54B/DDX1/SWI5/GEN1/TIMELESS/RECQL/LIG4/KDM4D/DCLRE1A/POLL/BRCA1/GINS4/MCM5/RTEL1/XRCC6/DCLRE1C/SWSAP1/TDP1/POLA1/PRPF19/TEX15/LIG3/POLB/VCP/MCM8/ZSWIM7/APLF/BRCC3/AUNIP/MGMT/WAS/PAXIP1/NUDT16/TONSL/NUCKS1/SPIDR/FEN1/RECQL4/FIGNL1	103
BP	GO:0051225	spindle assembly	47/7096	108/18670	0.1394	0.3358	0.2504	RAB11A/FLNA/SENP6/HAUS8/CHMP4B/KIF3B/CENPW/CSNK1D/CCDC155/KIF4A/MAPRE1/SPAG5/MAPRE2/KIF2A/RCC1/ASPM/ZNF207/HAUS2/NCOR1/CCDC69/SPICE1/BCCIP/MLH1/CHMP2A/TUBGCP3/CHMP1A/VPS4B/CEP63/TUBGCP5/GPSM2/HAUS5/HAUS1/TUBB1/SMC3/CDC20/RNF4/STAG1/MISP/RHOA/AURKA/KPNB1/MSTO1/SAC3D1/CHMP1B/NEK7/AAAS/WRAP73	47
BP	GO:2000278	regulation of DNA biosynthetic process	47/7096	108/18670	0.1394	0.3358	0.2504	KLF4/DUSP1/CDKN1A/MYC/RGCC/MAP3K4/HGF/PTK2B/PKIB/NAF1/HNRNPA1/HNRNPA2B1/DNAJC2/DSCC1/XRCC5/DCP2/PDGFB/NAT10/RFC3/PTGES3/ATM/MAPKAPK5/PARM1/HNRNPC/XRN1/PRKD2/PARP3/KCNK2/HNRNPD/CCT4/FBXO4/CCT8/ATR/MAPK1/ACD/CTC1/GNL3L/HSP90AB1/MEN1/PRKCQ/POT1/GJA1/GREM1/PNKP/NEK7/GRHL2/BMPR2	47
BP	GO:0002566	somatic diversification of immune receptors via somatic mutation	10/7096	19/18670	0.141	0.3376	0.2517	UNG/SAMHD1/PMS2P5/MLH1/POLL/EXO1/PMS2P3/MCM3AP/POLB/ADAR	10
BP	GO:0002710	negative regulation of T cell mediated immunity	10/7096	19/18670	0.141	0.3376	0.2517	SMAD7/PTPRC/HFE/LILRB1/IL7R/PPP3CB/HLA-F/IL20RB/HLA-G/TBX21	10
BP	GO:0003159	morphogenesis of an endothelium	10/7096	19/18670	0.141	0.3376	0.2517	RBPJ/STARD13/CXCL10/CSNK2B/ADAMTS12/FGF1/PRKD2/BMP4/FOXP1/RHOA	10
BP	GO:0032095	regulation of response to food	10/7096	19/18670	0.141	0.3376	0.2517	NUCB2/LEP/BBS2/MKKS/BBS4/PPARA/MTOR/SPX/NENF/GHRL	10
BP	GO:0034063	stress granule assembly	10/7096	19/18670	0.141	0.3376	0.2517	C9orf72/G3BP2/EIF2S1/ATXN2/PUM2/DDX3X/BICD1/ATXN2L/GRB7/PRKAA1	10
BP	GO:0042789	mRNA transcription by RNA polymerase II	10/7096	19/18670	0.141	0.3376	0.2517	STAT3/FLNA/ATF4/LMO2/HIF1A/SRF/ZBTB1/MYOG/ARNT/TFCP2	10
BP	GO:0045947	negative regulation of translational initiation	10/7096	19/18670	0.141	0.3376	0.2517	BANK1/AGO2/ATF4/RBM4/EIF2S1/EIF4EBP2/FMR1/EIF2AK1/EIF2AK4/PAIP2B	10
BP	GO:0048490	anterograde synaptic vesicle transport	10/7096	19/18670	0.141	0.3376	0.2517	BLOC1S2/AP3M2/DTNBP1/BLOC1S6/BLOC1S3/BLOC1S1/BLOC1S4/AP3B1/AP3M1/TRIM46	10
BP	GO:0061154	endothelial tube morphogenesis	10/7096	19/18670	0.141	0.3376	0.2517	RBPJ/STARD13/CXCL10/CSNK2B/ADAMTS12/FGF1/PRKD2/BMP4/FOXP1/RHOA	10
BP	GO:0099514	synaptic vesicle cytoskeletal transport	10/7096	19/18670	0.141	0.3376	0.2517	BLOC1S2/AP3M2/DTNBP1/BLOC1S6/BLOC1S3/BLOC1S1/BLOC1S4/AP3B1/AP3M1/TRIM46	10
BP	GO:0099517	synaptic vesicle transport along microtubule	10/7096	19/18670	0.141	0.3376	0.2517	BLOC1S2/AP3M2/DTNBP1/BLOC1S6/BLOC1S3/BLOC1S1/BLOC1S4/AP3B1/AP3M1/TRIM46	10
BP	GO:1901741	positive regulation of myoblast fusion	10/7096	19/18670	0.141	0.3376	0.2517	CAPN2/FLOT1/IL4R/CXCL9/CD53/FLT3LG/EHD1/MYOG/NFATC2/MYF6	10
BP	GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	10/7096	19/18670	0.141	0.3376	0.2517	PINK1/HIF1A/HSPB1/MAPK7/HTRA2/SIRT1/VNN1/NFE2L2/GPX1/BAG5	10
BP	GO:1902644	tertiary alcohol metabolic process	10/7096	19/18670	0.141	0.3376	0.2517	CBR4/AKR1B1/AKR1C3/AKR7A2/AKR1A1/BMP2/AKR1C1/BMP5/AKR1B10/CACNA1H	10
BP	GO:1903798	regulation of production of miRNAs involved in gene silencing by miRNA	10/7096	19/18670	0.141	0.3376	0.2517	MAP2K1/TGFB1/BCDIN3D/NCOR1/TARBP2/BMP4/MAP2K2/ZMPSTE24/EGFR/ZC3H10	10
BP	GO:2000010	positive regulation of protein localization to cell surface	10/7096	19/18670	0.141	0.3376	0.2517	LRIG2/TNF/TYROBP/SNX33/CD247/RANGRF/ABCA7/MAP1A/HSP90AB1/TM9SF4	10
BP	GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	19/7096	40/18670	0.1415	0.3382	0.2521	PTPN6/IL27RA/BCL6/SMAD7/IL4R/PTPRC/HFE/LILRB1/IL7R/PPP3CB/HLA-F/IL20RB/ZBTB7B/HLA-G/CR1/PARP3/TNFSF4/HAVCR2/TBX21	19
BP	GO:0008156	negative regulation of DNA replication	19/7096	40/18670	0.1415	0.3382	0.2521	ATG7/BCL6/CDAN1/FBXW7/SLFN11/S100A11/GMNN/GTPBP4/ZNF830/PDS5A/DONSON/TIPIN/ENPP7/RAD17/TIMELESS/ATR/SMC3/LIG3/ZRANB3	19
BP	GO:0019835	cytolysis	19/7096	40/18670	0.1415	0.3382	0.2521	MMD/P2RX7/LILRB1/TGFB1/GZMA/APOL1/GZMB/PGLYRP4/GZMM/RRAGA/PRF1/LYZL6/REG3G/GZMH/HRG/LBP/MICA/CFHR5/C7	19
BP	GO:2000008	regulation of protein localization to cell surface	19/7096	40/18670	0.1415	0.3382	0.2521	ARF6/KCNAB2/LRIG2/HFE/TNF/GOPC/TYROBP/SNX33/TOR1A/CD247/RANGRF/ABCA7/COMMD1/CAV3/MAP1A/ASTN2/HSP90AB1/TM9SF4/PICALM	19
BP	GO:0051282	regulation of sequestering of calcium ion	55/7096	128/18670	0.1427	0.3409	0.2542	SLC8A1/HTR2B/PTPN6/LYN/MCOLN1/TPCN1/DIAPH1/CXCL9/CXCL11/PTPRC/P2RX7/CXCL10/PKD2/TGFB1/ITPR1/PTK2B/MYO5A/CORO1A/P2RY6/RYR1/ABL1/GSTO1/PLCG2/DMD/TRPM2/LCK/CCR5/SRI/RASA3/ANXA6/BAX/PRKACA/CYBA/MCOLN2/F2R/CAMK2D/PLCB1/CEMIP/LETM1/CASQ1/CAPN3/CASQ2/HRC/BDKRB1/TMEM38B/LACRT/LIME1/SNCA/CX3CL1/CCL19/CHERP/ATP1A2/CCR7/MCOLN3/NTSR1	55
BP	GO:0006998	nuclear envelope organization	24/7096	52/18670	0.1428	0.3409	0.2542	SUN2/PPP2CA/LMNA/TMEM43/CHMP4B/UBXN2B/PAFAH1B1/EMD/NSFL1C/TOR1B/ANKLE2/BANF1/TOR1A/CHMP2A/NDEL1/ZMPSTE24/NUP93/VRK1/SPAG4/PARP11/LEMD3/REEP3/TARDBP/PRKCA	24
BP	GO:0045839	negative regulation of mitotic nuclear division	24/7096	52/18670	0.1428	0.3409	0.2542	DUSP1/MAD2L2/DYNC1LI1/RGCC/SPDL1/NAA10/KLHL22/CDK5RAP2/TOM1L1/TOM1L2/BMP7/ZNF207/LCMT1/ATM/BUB3/NDC80/BMP4/GEN1/ZW10/MTBP/CDC20/PCID2/AURKAIP1/IK	24
BP	GO:2000772	regulation of cellular senescence	24/7096	52/18670	0.1428	0.3409	0.2542	NAMPT/ARG2/BCL6/KRAS/EEF1E1/VASH1/ZKSCAN3/PLK2/ABL1/HMGA1/SIRT1/HLA-G/YPEL3/MIR34A/BMPR1A/ZMPSTE24/KIR2DL4/ARNTL/TERT/PNPT1/SLC30A10/NEK4/ZNF277/MIR146A	24
BP	GO:0006414	translational elongation	57/7096	133/18670	0.1432	0.3417	0.2548	MRPS6/DPH3/ALKBH1/SEPSECS/SECISBP2/MRPL35/TRNAU1AP/MRPL45/CHCHD1/MRPL40/SECISBP2L/MRPS30/MRPL34/DPH5/MRPS16/MRPS14/MRPL54/MRPL44/MRPL33/DPH2/USP16/GTPBP1/MRPL51/OXA1L/MRPL49/MRPL3/CPEB3/MRPL42/EEF1A2/DAP3/EIF5A/MRPS34/MRPL4/GADD45GIP1/MRPS33/MRPL20/MRPL46/MRPS18B/MRPL24/MRPL36/MRPS25/MRPS15/MRPL48/AURKAIP1/MRPL41/MRPL2/GFM1/MRPS2/MRPS9/DIO2/DNAJC24/CPEB2/NEMF/MRPL30/ABTB1/MRPL1/MRPS17	57
BP	GO:0042698	ovulation cycle	31/7096	69/18670	0.1443	0.3441	0.2565	RETN/PLEKHA1/EGR1/AXL/ARRB1/SGPL1/ZNF830/LEP/PTX3/HSPA5/CASP3/SIRT1/TIMP4/ETS1/PAM/PCNA/CASP2/INHBA/EGFR/FZD4/SLIT2/TGFB3/FSHR/OPRL1/TYRO3/NRIP1/BMPR1B/MMP19/FOXO3/KISS1/SLIT3	31
BP	GO:0036003	positive regulation of transcription from RNA polymerase II promoter in response to stress	16/7096	33/18670	0.1445	0.3441	0.2565	KLF2/RBPJ/CEBPB/ATF4/HIF1A/HSF2/MAPK7/HSF4/HSPA5/VEGFA/MUC1/CHD6/NFE2L2/MBTPS2/SESN2/ATF6B	16
BP	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	16/7096	33/18670	0.1445	0.3441	0.2565	LSM5/DCP1B/DCP2/LSM7/DCPS/EXOSC2/EDC4/EXOSC7/TTC37/CNOT7/EXOSC9/EXOSC3/EXOSC6/SKIV2L/EXOSC8/EXOSC5	16
BP	GO:0051443	positive regulation of ubiquitin-protein transferase activity	16/7096	33/18670	0.1445	0.3441	0.2565	PINK1/ARRDC4/FBXW7/UBE2N/DCUN1D1/ARRDC3/UBE2S/DCUN1D5/UBE2C/STUB1/DCUN1D3/CDC20/MASTL/PIN1/DCUN1D4/TOPORS	16
BP	GO:1901797	negative regulation of signal transduction by p53 class mediator	16/7096	33/18670	0.1445	0.3441	0.2565	MIF/CD44/CD74/PTTG1IP/SIRT1/ELL3/MUC1/BCL2/RFFL/DYRK3/RRM2B/MDM2/TAF9B/SNAI1/TRIAP1/ATAD5	16
BP	GO:0030194	positive regulation of blood coagulation	13/7096	26/18670	0.1452	0.3447	0.257	CD36/TLR4/THBD/HPSE/SERPINE1/PLEK/DMTN/F2R/NFE2L2/HRG/F3/ENPP4/SERPINF2	13
BP	GO:0030318	melanocyte differentiation	13/7096	26/18670	0.1452	0.3447	0.257	HPS4/KITLG/ZEB2/MYO5A/MITF/BCL2/HPS6/MREG/OCA2/RAB27A/GNA11/ADAMTS9/MEF2C	13
BP	GO:0035268	protein mannosylation	13/7096	26/18670	0.1452	0.3447	0.257	TMTC3/POMGNT2/FKRP/SDF2L1/DPY19L4/DPM1/TMTC2/POMT1/NUS1/POMT2/DPM3/DPY19L2/DPY19L2P2	13
BP	GO:0043090	amino acid import	13/7096	26/18670	0.1452	0.3447	0.257	RGS2/PER2/SLC7A11/CLN8/ARL6IP1/SLC7A1/SLC6A5/SLC36A4/PSEN1/SLC7A2/SLC25A38/ATP1A2/NTSR1	13
BP	GO:0048169	regulation of long-term neuronal synaptic plasticity	13/7096	26/18670	0.1452	0.3447	0.257	RAB11A/EPHB2/KRAS/HRAS/RAB8A/NPTN/RAB5A/SYNGAP1/APP/SNCA/SHANK3/CAMK2B/SYNPO	13
BP	GO:0070911	global genome nucleotide-excision repair	13/7096	26/18670	0.1452	0.3447	0.257	USP45/RNF111/RAD23B/ERCC4/DDB1/GTF2H4/ERCC1/UBC/CETN2/DDB2/ERCC2/CUL4B/RBX1	13
BP	GO:0080111	DNA demethylation	13/7096	26/18670	0.1452	0.3447	0.257	ALKBH1/TET2/USP9X/APOBEC3G/TDG/APOBEC3C/OTUD4/APOBEC2/FTO/USP7/APOBEC3B/ALKBH2/TET1	13
BP	GO:1900048	positive regulation of hemostasis	13/7096	26/18670	0.1452	0.3447	0.257	CD36/TLR4/THBD/HPSE/SERPINE1/PLEK/DMTN/F2R/NFE2L2/HRG/F3/ENPP4/SERPINF2	13
BP	GO:1990823	response to leukemia inhibitory factor	42/7096	96/18670	0.1455	0.3452	0.2574	KLF4/SOCS3/SBNO2/GCLM/PFKP/SMAD7/RFX2/SNX10/ABCD4/CTBP2/B3GNT2/TLE4/DTX1/PARP16/XRCC5/PML/SRSF3/CREB1/SIRT1/SLC25A5/GNPNAT1/NRP2/CTH/MYNN/SRSF7/KLF5/SPOCK2/KDM5B/CACYBP/SHMT1/FZD4/TFRC/SPRY2/SRM/BCLAF1/INA/BCAT2/WDR35/SMARCA5/GFPT2/PDCD10/KAT6B	42
BP	GO:1990830	cellular response to leukemia inhibitory factor	42/7096	96/18670	0.1455	0.3452	0.2574	KLF4/SOCS3/SBNO2/GCLM/PFKP/SMAD7/RFX2/SNX10/ABCD4/CTBP2/B3GNT2/TLE4/DTX1/PARP16/XRCC5/PML/SRSF3/CREB1/SIRT1/SLC25A5/GNPNAT1/NRP2/CTH/MYNN/SRSF7/KLF5/SPOCK2/KDM5B/CACYBP/SHMT1/FZD4/TFRC/SPRY2/SRM/BCLAF1/INA/BCAT2/WDR35/SMARCA5/GFPT2/PDCD10/KAT6B	42
BP	GO:1990542	mitochondrial transmembrane transport	44/7096	101/18670	0.1468	0.3482	0.2596	SFXN3/TIMM23B/SLC25A37/SLC25A20/SLC25A28/CPT2/MRS2/MCU/DNAJC19/DNAJC30/UCP2/TIMM17A/MPC2/ACACB/TIMM21/GRPEL1/SLC25A15/AFG3L2/PSEN2/SLC25A12/GRPEL2/TST/PRKAG2/TOMM40L/TOMM40/CPT1A/MICU1/UCP1/TOMM20/TIMM22/SLC25A33/SLC25A13/AGK/LETM1/DNAJC15/SLC25A22/SLC25A32/PNPT1/SLC25A38/TIMM50/THRSP/TIMM44/MICU2/TIMM9	44
BP	GO:0031670	cellular response to nutrient	33/7096	74/18670	0.1471	0.3486	0.2599	VDR/FYN/USF2/SOD1/PIM1/PTGS2/FOLR2/GDAP1/IL15/P2RX7/HMOX1/PDK2/LEP/BCL11A/SRF/BAIAP2/CDKN2B/P2RY12/TRPM4/NMRAL1/TRIM24/CYBA/CYBB/AMIGO1/HSP90B1/MDM2/P2RY4/CYP27B1/CIB2/SSH1/FGF23/NR1H4/P2RY1	33
BP	GO:0032507	maintenance of protein location in cell	33/7096	74/18670	0.1471	0.3486	0.2599	EZR/SUN2/PINK1/BARD1/TMSB10/SUPT7L/VPS13A/TWF2/TLN1/HSPA5/CDK5/SP100/PML/CLMN/GPAA1/BBS4/SYNE2/KDELR3/VPS13D/TLN2/KDELR2/SHANK1/FLNB/INSIG1/TXN/SCIN/SPAG4/CD4/TOPORS/DAG1/RER1/ARL2BP/OS9	33
BP	GO:0046879	hormone secretion	128/7096	312/18670	0.1472	0.3488	0.26	CRHBP/ANXA1/ACVR2B/LYN/RETN/SPP1/PPARD/HADH/SIRT4/SMAD2/ENY2/PER2/CYB5R4/JAK2/FAM3D/HFE/TNF/HMGCR/DPP4/LRP5/PPP3CB/ITPR1/AACS/ARRB1/HIF1A/FFAR2/PIM3/ENHO/MYO5A/LEP/MCU/AIMP1/TCIRG1/ITSN1/PAX8/IL1B/UQCC2/CCL5/C2CD2L/RAP1A/MPC2/LRP1/CREB1/RAF1/RFX3/IL1RN/TRPM4/DOC2B/RAC1/GLUD1/IL6/KALRN/IRS2/SLC25A5/KLF7/SERP1/SRI/OXCT1/RPH3AL/GPR27/SLC16A1/FFAR4/SYTL4/OSM/INHBA/CPT1A/PDX1/KDM5B/TM7SF3/PTPRN2/PFKFB2/HMGN3/RAB8B/EGFR/ICA1/NMB/CLOCK/FZD4/GIPR/GALR1/TCF7L2/EXOC3L1/LTBP4/BAD/SYT9/PLA2G6/HNF1B/IFNG/HNF1A/ARNTL/VIP/NPVF/SNX19/KIF5B/INHA/SNX4/REN/STXBP3/NDUFAF2/MAP4K4/SCG5/TRPV4/GHRH/SLC9B2/SOX4/SIDT2/ARL2BP/RIMS2/GCG/PFKL/FGF23/NLGN2/GJA1/NR1H4/TARDBP/STXBP4/PRKCA/UCN3/RBP4/PSMD9/C1QTNF3/P2RY1/TACR2/GHRL/KISS1/APLN/CCKAR/PHPT1	128
BP	GO:0051310	metaphase plate congression	26/7096	57/18670	0.1474	0.3488	0.26	NUP62/RAB11A/SPDL1/CHMP4B/PSRC1/SEH1L/CENPE/SPAG5/MIS12/CDC23/CENPC/CHAMP1/SPICE1/NDC80/MLH1/CHMP2A/NUF2/ZW10/CHMP1A/VPS4B/KIF2C/KPNB1/CHMP1B/RRS1/KIF14/BOD1	26
BP	GO:0075733	intracellular transport of virus	26/7096	57/18670	0.1474	0.3488	0.26	NUP62/NMT2/NUP160/NUP214/VPS37B/RAN/NUP85/SEH1L/NUP43/CD209/VPS37C/POM121/NUP88/TSG101/NUP107/UBAP1/UBC/NUP93/NUP205/FMR1/KPNA1/NUP50/TRIM15/KPNB1/POM121C/AAAS	26
BP	GO:1900408	negative regulation of cellular response to oxidative stress	26/7096	57/18670	0.1474	0.3488	0.26	FYN/ATG7/PINK1/TSC1/PSAP/SLC7A11/ATF4/HGF/HIF1A/HSPB1/MAPK7/HTRA2/NCOA7/SIRT1/LRRK2/VNN1/FZD1/NFE2L2/TXN/WNT1/NR4A3/GPX1/PDE8A/BAG5/MET/OXR1	26
BP	GO:1901799	negative regulation of proteasomal protein catabolic process	26/7096	57/18670	0.1474	0.3488	0.26	DDRGK1/LAMP3/HFE/FHIT/RYBP/ALAD/SGTA/OPHN1/SDCBP/UBE2J1/UCHL5/UBE2G2/KLHL40/DERL2/YOD1/USP7/MAP1A/UBXN1/OGT/HSP90AB1/CLEC16A/BAG5/USP19/SMARCC1/ERLEC1/OS9	26
BP	GO:0032456	endocytic recycling	21/7096	45/18670	0.1483	0.3506	0.2614	ARF6/ARL4C/DENND1A/DENND1B/MICALL1/CMTM6/EHD4/RAB11FIP4/EHD1/VPS51/MICALL2/CCDC93/INPP5F/VPS52/VPS29/RAB35/LMTK2/EHD3/SNX4/ACAP2/SNX17	21
BP	GO:1900274	regulation of phospholipase C activity	21/7096	45/18670	0.1483	0.3506	0.2614	HTR2B/S1PR4/FLT1/GNA15/PTAFR/GNAQ/LPAR2/P2RY6/HRAS/ABL1/P2RY12/ITK/BICD1/ARHGAP6/LPAR1/EGFR/ABL2/TXK/ADCYAP1R1/RASGRP4/NTRK2	21
BP	GO:0007032	endosome organization	35/7096	79/18670	0.1495	0.3532	0.2633	STAM/RAB11A/FAM160A2/SNX10/ALS2/SQSTM1/AQP11/VPS37B/CHMP4B/SYNJ1/TMCC1/CLCN3/LAMTOR1/VPS37C/VTA1/HOOK2/SNX33/TMEM127/DNM1/HOOK3/VPS18/CHMP2A/TSG101/PI4K2A/IST1/HGS/CHMP1A/VPS4B/CORO1C/VPS25/LAPTM4B/RAB22A/ALS2CL/CHMP1B/RAB27A	35
BP	GO:0010811	positive regulation of cell-substrate adhesion	52/7096	121/18670	0.1503	0.3551	0.2647	MYADM/S100A10/FN1/TSC1/ITGA5/NEDD9/FLNA/CIB1/JAK2/GSK3B/CD36/PTK2B/NINJ1/VEGFA/ABL1/CRK/PPM1F/RAC1/DOCK5/RELL2/EMILIN3/EMP2/NRP1/DISC1/DNM2/UNC13D/TRIOBP/SPOCK2/ITGA3/DMTN/CALR/C1QBP/PREX1/EMID1/APOA1/SKAP1/HRG/NID1/ARPC2/PRKCZ/MAP4K4/LIMS1/DAG1/CX3CL1/ITGB1BP1/FOXF1/CCR7/CD3E/EMILIN2/HSD17B12/PTPRJ/FMN1	52
BP	GO:0051896	regulation of protein kinase B signaling	101/7096	244/18670	0.1515	0.3576	0.2666	KLF4/FYN/CX3CR1/RAC2/PINK1/RNF41/PLEKHA1/BANK1/KITLG/CIB1/RRAS/ADAM8/TNF/AKR1C3/GAB1/HCLS1/AXL/TGFB1/HGF/LEP/INSR/NRG1/HYAL2/RHOG/ARFGEF1/ITSN1/IGF1R/P2RY12/SIRT1/HLA-G/MFHAS1/RAC1/CHI3L1/IRS2/LCK/PDGFB/FGF1/PPP2R5C/FLCN/PTK2/MIR34A/HPSE/TRAT1/INPP5K/PIK3CD/THEM4/OSM/TSPYL5/GRB2/INPP5F/PDGFA/ICOS/SEMA5A/BTN2A2/C1QBP/VAV1/EGFR/KLB/TXN/MUL1/IL18/CAV3/SPRY2/KL/CPNE1/TCF7L2/OTUD3/RET/GCNT2/HBEGF/PKHD1/MAZ/HSP90AB1/PPP2R5B/PIK3CG/PHLPP2/F3/MTDH/GPX1/CD80/MTOR/MEIS3/RTN4/DAG1/CX3CL1/ITGB1BP1/IAPP/ENG/CCL19/MET/CCR7/SFRP5/FGF23/IL26/ERBB3/RASD2/THPO/NTRK2/FGF6/PIK3CB/PTPRJ	101
BP	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	37/7096	84/18670	0.1515	0.3576	0.2666	KLF4/SERPINB9/CDKN2D/POR/PTGS2/SH3RF1/RPS6KA3/BIRC2/CD44/LAMP3/MICAL1/HGF/ARL6IP1/ARRB1/VEGFA/SFN/PAK2/RAF1/PLAUR/DNAJB6/DDX3X/FNIP1/MMP9/BIRC3/RFFL/BIRC7/LAMTOR5/CAAP1/MDM2/YWHAE/IGBP1/MAP2K5/GPX1/TRIAP1/SNCA/XIAP/SIAH2	37
BP	GO:0007259	JAK-STAT cascade	66/7096	156/18670	0.152	0.3586	0.2673	IGF1/CCR2/FYN/SOCS3/LYN/PPP2CA/PARP9/AKR1B1/STAT6/STAT3/PTPN2/ADIPOR1/CD40/STAT1/JAK2/PTPRC/IL15/IFNAR1/TNF/ERCC6/PKD2/DOT1L/HCLS1/NMI/CYP1B1/SOCS5/LEP/FLT3/SOCS6/STAT5A/PTK6/CCL5/TNFRSF18/IL6ST/IL6/HDAC2/CLCF1/IFNK/OSM/HGS/DAB1/CD300A/INPP5F/FER/HES1/F2R/PWP1/CNTF/CNOT7/IL18/STAMBP/SOCS1/IL3/TSLP/IFNG/TNFSF18/RET/IFNAR2/IL12B/CSF1R/ARL2BP/GHR/IL26/SOCS2/IL23A/MIR146A	66
BP	GO:0007340	acrosome reaction	18/7096	38/18670	0.1533	0.3607	0.2689	STXBP1/UNC13B/PLB1/SPINK1/SYT6/CCDC87/ADCY3/FAM170B/HYAL3/PLCB1/C11orf74/PLCD4/RAB3A/B4GALT1/ACR/CACNA1H/POMZP3/SPESP1	18
BP	GO:0010831	positive regulation of myotube differentiation	18/7096	38/18670	0.1533	0.3607	0.2689	CAPN2/FLOT1/IL4R/CXCL9/CD53/FLT3LG/EHD1/MYOG/BCL2/CYP26B1/NFATC2/MAMSTR/MMP14/LMOD3/CAV3/SHOX2/MTOR/MYF6	18
BP	GO:0032094	response to food	18/7096	38/18670	0.1533	0.3607	0.2689	BCL10/TMEM135/SLC25A25/NUCB2/LEP/BBS2/MKKS/G6PD/BBS4/SLC16A1/PPARA/MTOR/GHRH/SPX/NENF/MPO/G6PC/GHRL	18
BP	GO:0045494	photoreceptor cell maintenance	18/7096	38/18670	0.1533	0.3607	0.2689	SPATA7/DRAM2/ERCC6/BBS10/CLN8/BBS2/BBS12/MKKS/RDH12/BBS4/NPHP4/MAK/LCA5/NXNL1/ESRRB/CIB2/TULP1/RP1	18
BP	GO:0010718	positive regulation of epithelial to mesenchymal transition	23/7096	50/18670	0.1539	0.3607	0.2689	GLIPR2/SMAD2/RGCC/EZH2/TGFB1/LOXL2/BMP2/IL1B/SDCBP/BMP7/IL6/BCL9L/HDAC2/ZNF703/BMP4/OLFM1/TCF7L2/TGFB3/SNAI1/TGFB1I1/GCNT2/MTOR/ENG	23
BP	GO:1903793	positive regulation of anion transport	23/7096	50/18670	0.1539	0.3607	0.2689	ATP8A1/MIF/CEBPB/P2RX7/APOE/PRELID1/ATF4/STXBP1/ARL6IP1/PTAFR/PRKCD/RAB3GAP1/IL1B/TNFRSF11A/FABP3/ABCB4/ABCA7/PSEN1/APOA1/PLA2G6/SYT4/TRIAP1/NTSR1	23
BP	GO:0001522	pseudouridine synthesis	9/7096	17/18670	0.1541	0.3607	0.2689	NAF1/PUS7L/RPUSD2/PUS1/NHP2/GAR1/RPUSD3/PUS7/NOP10	9
BP	GO:0006744	ubiquinone biosynthetic process	9/7096	17/18670	0.1541	0.3607	0.2689	COQ7/COQ5/PDSS1/COQ3/COQ10B/COQ9/COQ6/COQ10A/COQ4	9
BP	GO:0009070	serine family amino acid biosynthetic process	9/7096	17/18670	0.1541	0.3607	0.2689	SEPHS2/PSPH/SHMT2/SERINC3/CTH/AGXT2/SHMT1/SRR/PHGDH	9
BP	GO:0030540	female genitalia development	9/7096	17/18670	0.1541	0.3607	0.2689	WNT5A/SRD5A1/AXL/BAX/MERTK/TYRO3/BAK1/RBP4/STRA6	9
BP	GO:0034433	steroid esterification	9/7096	17/18670	0.1541	0.3607	0.2689	STARD4/APOC1/SOAT1/APOE/LAMTOR1/APOA5/LCAT/ABCG1/APOA1	9
BP	GO:0034434	sterol esterification	9/7096	17/18670	0.1541	0.3607	0.2689	STARD4/APOC1/SOAT1/APOE/LAMTOR1/APOA5/LCAT/ABCG1/APOA1	9
BP	GO:0034435	cholesterol esterification	9/7096	17/18670	0.1541	0.3607	0.2689	STARD4/APOC1/SOAT1/APOE/LAMTOR1/APOA5/LCAT/ABCG1/APOA1	9
BP	GO:0034501	protein localization to kinetochore	9/7096	17/18670	0.1541	0.3607	0.2689	SPDL1/MIS12/CHAMP1/BUB3/NDC80/ZW10/RCC2/MTBP/IK	9
BP	GO:0042249	establishment of planar polarity of embryonic epithelium	9/7096	17/18670	0.1541	0.3607	0.2689	WNT5A/DVL2/PAFAH1B1/FZD1/DVL1/CTHRC1/FOXF2/FZD2/GRHL3	9
BP	GO:0048311	mitochondrion distribution	9/7096	17/18670	0.1541	0.3607	0.2689	MEF2A/TRAK2/LRRK2/SLC4A5/DNM1L/KAT2A/TRAK1/ATCAY/MSTO1	9
BP	GO:0071360	cellular response to exogenous dsRNA	9/7096	17/18670	0.1541	0.3607	0.2689	FLOT1/DDX58/DHX9/MAVS/IFIH1/IFIT1/MUL1/TLR3/ZCCHC3	9
BP	GO:0090185	negative regulation of kidney development	9/7096	17/18670	0.1541	0.3607	0.2689	STAT1/PAX8/BMP7/FLCN/MMP9/BMP4/HNF1B/TACSTD2/WT1	9
BP	GO:0099010	modification of postsynaptic structure	9/7096	17/18670	0.1541	0.3607	0.2689	CTTNBP2/PFN1/STAU1/BAIAP2/ITSN1/CAMKV/CYFIP1/RHOA/SYNPO	9
BP	GO:1901663	quinone biosynthetic process	9/7096	17/18670	0.1541	0.3607	0.2689	COQ7/COQ5/PDSS1/COQ3/COQ10B/COQ9/COQ6/COQ10A/COQ4	9
BP	GO:1904355	positive regulation of telomere capping	9/7096	17/18670	0.1541	0.3607	0.2689	MAP3K4/PKIB/MAPKAPK5/HNRNPD/MAPK1/RTEL1/PRKCQ/PNKP/NEK7	9
BP	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell	9/7096	17/18670	0.1541	0.3607	0.2689	CCR2/TNF/RELA/PTAFR/TRAF6/ITGA4/ETS1/NFAT5/RHOA	9
BP	GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	147/7096	361/18670	0.1545	0.3615	0.2695	MYO1G/CCR2/NFKBIZ/PTPN6/IL27RA/ANXA1/STX7/BCL10/MAD2L2/CD55/IRF7/C1RL/SLC11A1/STAT6/STAT3/BCL6/NLRP3/SMAD7/TNFAIP3/CD40/CD1C/FGL2/CTSC/LY9/IL4R/PTPRC/P2RX7/CD1E/HFE/BATF/TNF/CD74/LILRB1/IL7R/DENND1B/CD226/TGFB1/PPP3CB/IL18R1/POU2F2/UNG/SOCS5/TNFSF13B/SWAP70/PRKCD/IL18BP/FAM49B/HLA-F/TRAF6/NFKB2/ZBTB1/CLC/CXCL13/TCIRG1/SEMA4A/IL20RB/TLR4/ZBTB7B/HLA-E/HLA-B/HRAS/RELB/RSAD2/NFKBID/IL1B/FBXO38/AGER/CD1B/HMGB1/CLU/TRPM4/IL1R1/HLA-G/SERPING1/TRBC1/IL6/CR1/HLA-C/BTN3A2/EMP2/FCER2/MLH1/PARP3/ERCC1/CLCF1/CCR6/UNC13D/BTN3A3/PVR/CR2/CD1D/IL12RB1/CD1A/CD274/EBI3/LIG4/C1R/FZD5/GZMM/ADA/HLX/ULBP2/C1QBP/IL18/FADD/ADAM17/TRAF2/TFRC/PRF1/TNFSF4/TLR8/IL13RA2/EXO1/C1QC/HLA-A/RORA/HAVCR2/SCART1/EXOSC3/CD4/GAPT/TNFRSF13C/IL12B/SLA2/MICA/PRKCZ/CD80/TBX21/MTOR/PRKCQ/IL18RAP/APLF/EXOSC6/CCL19/MALT1/MASP2/CD8A/WAS/PAXIP1/ATAD5/RAB27A/IL23A/APCS/IGHD/MEF2C/C7/RFTN1	147
BP	GO:0042158	lipoprotein biosynthetic process	41/7096	94/18670	0.1547	0.3618	0.2697	ATG7/ZDHHC20/NMT2/PIGV/PIGP/ABHD17C/PIGK/APOE/ZDHHC9/PIGN/RAB3GAP1/ABCA1/ZDHHC6/WIPI1/PIGF/PIGB/DPM1/ZDHHC5/GPAA1/PIGM/LCAT/MPPE1/HHAT/PIGQ/WDR45B/ZDHHC16/PIGO/UGCG/PIGH/ZDHHC14/DPM3/ZDHHC2/APOA1/ZDHHC18/PIGT/CLIP3/ZDHHC12/ZDHHC21/PGAP3/PGAP1/ATG12	41
BP	GO:0006482	protein demethylation	15/7096	31/18670	0.1571	0.3653	0.2724	JMJD6/KDM1B/KDM7A/HSF4/KDM2A/ALKBH4/KDM4B/KDM2B/KDM8/KDM5B/KDM6B/KDM4D/KDM5C/UBE2B/KDM4A	15
BP	GO:0007202	activation of phospholipase C activity	15/7096	31/18670	0.1571	0.3653	0.2724	HTR2B/S1PR4/GNA15/GNAQ/LPAR2/P2RY6/P2RY12/ITK/ARHGAP6/LPAR1/EGFR/TXK/ADCYAP1R1/RASGRP4/NTRK2	15
BP	GO:0008214	protein dealkylation	15/7096	31/18670	0.1571	0.3653	0.2724	JMJD6/KDM1B/KDM7A/HSF4/KDM2A/ALKBH4/KDM4B/KDM2B/KDM8/KDM5B/KDM6B/KDM4D/KDM5C/UBE2B/KDM4A	15
BP	GO:0010762	regulation of fibroblast migration	15/7096	31/18670	0.1571	0.3653	0.2724	SLC8A1/APPL2/TGFB1/PAK1/HYAL2/C5orf30/WDPCP/RFFL/FER/DMTN/CORO1C/RCC2/ITGB1BP1/MTA2/APPL1	15
BP	GO:0030149	sphingolipid catabolic process	15/7096	31/18670	0.1571	0.3653	0.2724	ASAH1/HEXB/GM2A/PSAP/SGPL1/GALC/PRKCD/GLA/ENPP7/SPHK1/NAGA/ACER3/NEU1/SMPD1/SMPD2	15
BP	GO:0032786	positive regulation of DNA-templated transcription, elongation	15/7096	31/18670	0.1571	0.3653	0.2724	PAF1/ERCC6/ALYREF/GTF2F2/ELL3/CDK9/SCAF8/CCNK/SUPT4H1/GTF2F1/THOC5/LEO1/SUPT16H/CCNT1/CDC73	15
BP	GO:0036257	multivesicular body organization	15/7096	31/18670	0.1571	0.3653	0.2724	STAM/RAB11A/VPS37B/CHMP4B/VPS37C/VTA1/CHMP2A/TSG101/IST1/HGS/CHMP1A/VPS4B/VPS25/CHMP1B/RAB27A	15
BP	GO:0044319	wound healing, spreading of cells	15/7096	31/18670	0.1571	0.3653	0.2724	ITGA5/FLNA/RHOC/CD44/CD151/MMP12/TOR1A/CLASP2/ADAM17/HBEGF/TMEFF2/MTOR/RHOA/PDCD10/WNT7A	15
BP	GO:0045648	positive regulation of erythrocyte differentiation	15/7096	31/18670	0.1571	0.3653	0.2724	STAT3/STAT1/FAM210B/HIF1A/ISG15/ACVR1B/TAL1/ETS1/HMGB2/ID2/INHBA/ARNT/TRIM58/PRMT1/FOXO3	15
BP	GO:0050685	positive regulation of mRNA processing	15/7096	31/18670	0.1571	0.3653	0.2724	TRA2B/PAF1/DAZAP1/THRAP3/RBMXL1/RBM3/PRDX6/CPEB1/SF3B4/CPEB3/LEO1/PRPF19/CELF3/HMX2/CDC73	15
BP	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway	15/7096	31/18670	0.1571	0.3653	0.2724	S1PR1/GNA15/P2RY8/LPAR6/C3AR1/TGM2/LPAR3/GPR18/LPAR1/F2R/GPR35/OPRL1/P2RY10/GPR20/KISS1	15
BP	GO:0060292	long-term synaptic depression	15/7096	31/18670	0.1571	0.3653	0.2724	LILRB2/ABHD6/STXBP1/PTK2B/SRF/PLK2/AGER/ARC/ARF1/SORCS2/FMR1/CBLN1/PICK1/SLC24A2/SHANK3	15
BP	GO:0090505	epiboly involved in wound healing	15/7096	31/18670	0.1571	0.3653	0.2724	ITGA5/FLNA/RHOC/CD44/CD151/MMP12/TOR1A/CLASP2/ADAM17/HBEGF/TMEFF2/MTOR/RHOA/PDCD10/WNT7A	15
BP	GO:1902253	regulation of intrinsic apoptotic signaling pathway by p53 class mediator	15/7096	31/18670	0.1571	0.3653	0.2724	MIF/CD44/CD74/PTTG1IP/HNRNPK/SIRT1/ELL3/MUC1/BCL2/RRM2B/MDM2/TAF9B/MSX1/TRIAP1/ATAD5	15
BP	GO:2000781	positive regulation of double-strand break repair	15/7096	31/18670	0.1571	0.3653	0.2724	MAD2L2/PARP9/SPIRE1/ACTR2/SETMAR/SMCHD1/DTX3L/PARP3/FUS/TIMELESS/KDM4D/MGMT/WAS/NUDT16/SPIDR	15
BP	GO:0099504	synaptic vesicle cycle	81/7096	194/18670	0.1572	0.3653	0.2724	APBA1/ARF6/STX11/DNM3/RAP1B/SYT11/POTEKP/FCHO2/DENND1A/STXBP5/P2RX7/CTBP2/GSK3B/PLAA/PLD1/ACTB/PPP3CB/STXBP1/UNC13B/GRIPAP1/SYNJ1/FBXL20/ITSN1/CDK5/CLCN3/OPHN1/RAB3GAP1/DTNBP1/RAP1A/BLOC1S6/DOC2B/PREPL/LRRK2/CYFIP1/ADCY1/DNAJC6/TOR1A/SH3GL1/DNM1/P2RX1/ADORA2B/VPS18/NAPA/DNM2/RAB5A/KIAA1107/CAMK2A/CANX/CHRM2/DNM1L/CHRNA4/AP3B1/ATP2A2/PLD2/DVL1/PSEN1/FMR1/RAB3A/CHRNB2/P2RY4/PPFIA3/SYT9/SYT1/RAB3B/SYT2/VAMP1/DOC2A/SNAP29/SYT4/CADPS2/SYT5/BRSK1/SNCA/RIMS2/WNT7A/PICALM/NLGN2/SYN3/KIAA1109/P2RY1/AMPH	81
BP	GO:0032272	negative regulation of protein polymerization	32/7096	72/18670	0.1573	0.3653	0.2724	MYADM/STMN1/TMSB10/TMOD3/TWF2/RDX/PFN1/CAPZA2/PRKCD/ARFGEF1/CAPG/CAPZA1/MAPRE1/MKKS/SPTBN1/CDH5/BBS4/AVIL/KANK1/TRIOBP/ADD3/VDAC2/DMTN/LMOD3/SCIN/SLIT2/TUBB4A/SPTA1/SPTBN2/KANK3/SNCA/CLIP3	32
BP	GO:0051155	positive regulation of striated muscle cell differentiation	32/7096	72/18670	0.1573	0.3653	0.2724	IGF1/TRIM32/RBPJ/CAPN2/FLOT1/IL4R/CXCL9/MORF4L2/CD53/TGFB1/NRG1/FLT3LG/PARP2/EHD1/MESP1/MYOG/BCL2/BMP4/CYP26B1/NFATC2/MAMSTR/MMP14/LMOD3/CAV3/KAT2A/HAMP/SHOX2/PIN1/MTOR/GREM1/MEF2C/MYF6	32
BP	GO:0060193	positive regulation of lipase activity	32/7096	72/18670	0.1573	0.3653	0.2724	HTR2B/S1PR4/FLT1/RHOC/GNA15/PLAA/PTAFR/GNAQ/LPAR2/ARF4/NR1H2/P2RY6/HRAS/CCL5/LMF1/P2RY12/ITK/APOA5/ARHGAP6/NMUR2/NR1H3/ARL1/LPAR1/EGFR/ABL2/GNA13/TXK/PRKCZ/RHOA/ADCYAP1R1/RASGRP4/NTRK2	32
BP	GO:0009110	vitamin biosynthetic process	12/7096	24/18670	0.1584	0.3661	0.2729	VDR/CYP27A1/TNF/NFKB1/AKR1A1/IL1B/RFK/MMAB/MMACHC/CYP27B1/SNAI1/IFNG	12
BP	GO:0009218	pyrimidine ribonucleotide metabolic process	12/7096	24/18670	0.1584	0.3661	0.2729	UPP1/AK3/CTPS2/CMPK1/NME3/NME4/NME1/UCK1/CTPS1/CAD/UCKL1/UPP2	12
BP	GO:0014850	response to muscle activity	12/7096	24/18670	0.1584	0.3661	0.2729	METRNL/SRD5A1/FNDC5/FIS1/HIF1A/PPARGC1A/MYOG/ITGA2/GOT2/TOMM20/CAPN3/MTFP1	12
BP	GO:0032528	microvillus organization	12/7096	24/18670	0.1584	0.3661	0.2729	EZR/PLS1/RAPGEF6/FXYD5/PLD1/TWF2/RDX/RAPGEF2/ATP8B1/KLF5/FSCN1/GLDN	12
BP	GO:0032897	negative regulation of viral transcription	12/7096	24/18670	0.1584	0.3661	0.2729	TRIM32/ZFP36/TRIM13/IFITM3/TFAP4/CCL5/TRIM11/TRIM21/INPP5K/MID2/CCL4/TARDBP	12
BP	GO:0033119	negative regulation of RNA splicing	12/7096	24/18670	0.1584	0.3661	0.2729	TMBIM6/RNPS1/RBM42/SRSF10/HNRNPK/HNRNPA2B1/SFSWAP/SRSF6/SRSF7/C1QBP/SRSF4/SAP18	12
BP	GO:0036315	cellular response to sterol	12/7096	24/18670	0.1584	0.3661	0.2729	LRP8/AACS/HMGCS1/ABCA1/MLC1/INHBA/NFE2L1/INSIG1/RORA/DAG1/SMO/PTCH1	12
BP	GO:0046639	negative regulation of alpha-beta T cell differentiation	12/7096	24/18670	0.1584	0.3661	0.2729	ANXA1/BCL6/SMAD7/IL4R/CBFB/SOCS5/ZBTB7B/HMGB1/HLX/TNFSF4/SOCS1/TBX21	12
BP	GO:0051220	cytoplasmic sequestering of protein	12/7096	24/18670	0.1584	0.3661	0.2729	FLNA/KEAP1/G3BP2/NFKBIA/PKD2/LATS1/GOPC/SRI/GET4/NFKBIE/MXI1/TONSL	12
BP	GO:0060148	positive regulation of posttranscriptional gene silencing	12/7096	24/18670	0.1584	0.3661	0.2729	ZFP36/STAT3/MAP2K1/AGO2/TGFB1/DHX9/PUM2/BMP4/MAP2K2/EGFR/FMR1/EIF4G1	12
BP	GO:1900078	positive regulation of cellular response to insulin stimulus	12/7096	24/18670	0.1584	0.3661	0.2729	ADIPOR1/GKAP1/PAK1/LEP/ZBTB7B/SIRT1/MYO1C/GNAI2/SERPINA12/PRKCZ/NUCKS1/NR1H4	12
BP	GO:1902410	mitotic cytokinetic process	12/7096	24/18670	0.1584	0.3661	0.2729	KLHDC8B/NUP62/CHMP4B/ARF1/CEP55/CHMP2A/KIF20B/CHMP1A/VPS4B/BIN3/RHOA/CHMP1B	12
BP	GO:0002090	regulation of receptor internalization	25/7096	55/18670	0.1585	0.3661	0.2729	FLOT1/TBC1D5/ARRB1/LRPAP1/CD63/USP46/VEGFA/OPHN1/NUMB/PLCG2/SDCBP/SFRP4/ATXN2/ARC/ARF1/UBQLN2/MTMR2/FMR1/MKLN1/ANKRD13D/PICK1/GSG1L/ATAD1/GREM1/APLN	25
BP	GO:0042304	regulation of fatty acid biosynthetic process	25/7096	55/18670	0.1585	0.3661	0.2729	PDK4/ANXA1/PTGS2/ADIPOR1/SLC45A3/APOC1/CD74/ELOVL5/LPGAT1/EIF6/NR1H2/ERLIN1/IL1B/ERLIN2/SIRT1/APOA5/PRKAG2/SCAP/NR1H3/ACADVL/INSIG1/FABP5/BRCA1/ADIPOR2/ABCD1	25
BP	GO:0042306	regulation of protein import into nucleus	25/7096	55/18670	0.1585	0.3661	0.2729	NUP62/PTGS2/CHP1/FLNA/RAN/HCLS1/TGFB1/RAB23/CD36/LEP/PRKCD/HYAL2/ZPR1/UBR5/MDFIC/MAVS/NOLC1/BMP4/PSEN1/MAPK1/IFNG/CHP2/PKIA/SMO/TARDBP	25
BP	GO:0043954	cellular component maintenance	25/7096	55/18670	0.1585	0.3661	0.2729	FYN/ARF6/PLEKHA7/CTBP2/APOE/INSR/KIFC3/IGF1R/OPHN1/CHCHD10/HOMER1/SYNGAP1/MTMR2/ITGA3/TPRN/F2R/C1QL1/RAB3A/SUPV3L1/PKP2/CSF1R/PRTN3/PICK1/NLGN2/ZMYND8	25
BP	GO:0044273	sulfur compound catabolic process	25/7096	55/18670	0.1585	0.3661	0.2729	HEXB/VCAN/PCYOX1/AHCY/IDS/ACOT7/HEXA/ARSB/GNS/MTRR/CSPG4/IDUA/PCYOX1L/MLYCD/TST/MPST/CTH/BCAN/NUDT7/GGT7/GGT5/CHAC2/ABCD1/GGTLC1/MAT1A	25
BP	GO:2001252	positive regulation of chromosome organization	73/7096	174/18670	0.1589	0.3667	0.2734	PINK1/LMNA/BCL6/PHF19/CHTOP/UBE2N/ZNF304/PAF1/MAP3K4/TGFB1/SMC5/SIN3A/ARRB1/MORC2/PKIB/RUVBL2/NAF1/ZBTB7B/KAT7/HNRNPA1/VEGFA/HNRNPA2B1/IL1B/NSMCE2/XRCC5/MIER1/PML/SIRT1/SFPQ/PAXBP1/CDK9/LRRK2/PPARGC1A/TAL1/ESPL1/ATM/ANAPC5/MUC1/MAPKAPK5/KMT2E/AKAP8/PRKD2/ERCC1/SETDB1/HNRNPD/LIG4/CCT4/RNF20/FBXO4/CCT8/BRCA1/ATR/KAT2A/FMR1/MAPK1/DLGAP5/RTEL1/ACD/ANAPC4/OGT/RB1/JDP2/PRKCQ/ANAPC11/POT1/PAX7/GCG/PAXIP1/GNL3/PNKP/FEN1/NEK7/TET1	73
BP	GO:0050728	negative regulation of inflammatory response	71/7096	169/18670	0.1592	0.3673	0.2738	KLF4/IGF1/FPR2/PTGER4/METRNL/ACP5/IL1R2/APPL2/GRN/SOCS3/SOD1/PTPN2/NLRP3/PPARD/DUSP10/TNFAIP3/NLRP12/GSTP1/PTPRC/SIGLEC10/NFKB1/APOE/CHID1/HGF/TNFAIP6/SOCS5/MAPK7/PSMA1/PRKCD/IL20RB/ABR/C5orf30/NR1D2/AGER/LDLR/MFHAS1/ADCY7/CDH5/CD200R1/BCR/ETS1/WFDC1/CST7/RPS19/ASH1L/MEFV/NR1H3/FFAR4/RABGEF1/CNR2/ADA/PPARA/APOA1/RORA/NLRX1/RB1/IL12B/GPX1/TYRO3/CX3CL1/PDCD4/ABCD1/FOXF1/PSMB4/NR1H4/NLRC3/SLAMF8/C1QTNF3/MIR205/APCS/GHRL	71
BP	GO:0071482	cellular response to light stimulus	55/7096	129/18670	0.1597	0.3683	0.2746	CRIP1/BMF/CDKN1A/NMT2/PTGS2/GNB1/MYC/ERCC4/ATF4/MAPK13/METTL3/USP28/RUVBL2/ZBTB1/HYAL2/TMEM161A/DDB1/NPM1/METAP2/PDE6G/SIRT1/EIF2S1/RHNO1/POLH/ACTR5/PCNA/NEDD4/BAX/NOC2L/ERCC1/YY1/CDC25A/OPN3/ST20/HYAL3/SDE2/IMPACT/C9orf116/E2F4/ATR/FMR1/MDM2/DDB2/GUCY2D/POLD1/RBL2/CUL4B/GRK4/GPR52/EIF2AK4/TRIAP1/BAK1/RGR/RP1/OPN4	55
BP	GO:0030866	cortical actin cytoskeleton organization	20/7096	43/18670	0.1603	0.3695	0.2754	EZR/PLS1/ARF6/FMNL3/FMNL1/TNF/TLN1/EPB41L1/CDK5/WIPF2/RHOQ/PLEK/CALR/EPB41/LLGL1/WIPF1/EPB41L2/WAS/ROCK2/NCKAP1	20
BP	GO:0045687	positive regulation of glial cell differentiation	20/7096	43/18670	0.1603	0.3695	0.2754	TLR2/MIR142/RELA/TGFB1/BMP2/IL6ST/ZNF488/TTBK1/DICER1/HDAC2/ID2/CLCF1/SPINT1/PRMT5/HES1/PRPF19/MTOR/DAG1/PTPRZ1/BIN1	20
BP	GO:0001505	regulation of neurotransmitter levels	144/7096	354/18670	0.1611	0.3712	0.2768	KLF4/NQO1/KLF2/CX3CR1/APBA1/TLR2/ATP2B4/ACP5/GCH1/CLEC7A/SLC29A1/STX11/POR/ARG2/SRD5A1/RAP1B/SYT11/ALDH9A1/PTGS2/RGS2/FLOT1/ALDH7A1/PER2/JAK2/P2RX7/CTBP2/KCNC4/TNF/SLC7A11/DDAH2/HNMT/PKD2/GSK3B/TICAM1/STXBP1/CLN8/UNC13B/CYP1B1/ARL6IP1/CD36/PTK2B/SYNJ1/PNKD/INSR/HBB/PTX3/TLR4/FBXL20/MAOA/CDK5/DPYD/RAB3GAP1/IL1B/DTNBP1/AIF1/CLN3/RAP1A/BLOC1S6/AASDH/CLU/DOC2B/RAC1/GLA/PREPL/LRRK2/ALDH5A1/SLC38A1/ADCY1/SPR/PDZD11/TOR1A/DAGLB/SHMT2/P2RX1/ADORA2B/SLC6A5/VPS18/NAPA/DNM2/PPFIA4/CD47/BHMT/RAB5A/SLC29A2/PTPRN2/CAMK2A/CHRM2/CHKA/DNM1L/CHRNA4/AGXT2/SHMT1/LIN7C/TPH2/ATP2A2/MAOB/AMT/DVL1/PSEN1/SYNGR3/FMR1/RAB3A/CHRNB2/P2RY4/PPFIA3/SYT9/RORA/IFNG/ATP7A/SLC7A2/SYT1/CD34/RAB3B/HSP90AB1/DBH/SYT2/WDR35/VAMP1/DOC2A/SNAP29/SYT4/CADPS2/SNCAIP/SYT5/MTOR/LRTOMT/CHAT/BRSK1/SNCA/KCNMB4/SLC25A32/CHDH/RIMS2/ATP1A2/WNT7A/ROCK2/PHGDH/SYN3/TLR6/P2RY1/TACR2/NTSR1/MEF2C/GCHFR	144
BP	GO:0006855	drug transmembrane transport	36/7096	82/18670	0.1615	0.3719	0.2773	SLC47A1/SLC19A2/SLC25A19/SLC22A18/RGS2/SLC38A7/FOLR2/PER2/SLC7A11/CLN8/ARL6IP1/PRAF2/SLC7A5/SLC25A10/ATP8B1/SLC25A15/SLC7A1/SLC25A12/SLC6A5/SLC46A1/OSCP1/SLC36A4/SLC25A13/SLC25A26/PSEN1/RALBP1/SLC7A2/TMEM30A/SLC25A22/SLC25A32/SLC25A38/ATP1A2/SLC4A11/SLC38A9/NTSR1/STRA6	36
BP	GO:0051784	negative regulation of nuclear division	27/7096	60/18670	0.1623	0.3735	0.2785	DUSP1/MAD2L2/DYNC1LI1/RGCC/SPDL1/RAD1/NAA10/KLHL22/CDK5RAP2/TOM1L1/TOM1L2/BMP7/ZNF207/LCMT1/ATM/BUB3/NDC80/BMP4/GEN1/ZW10/MOS/MTBP/CDC20/PCID2/AURKAIP1/IK/HORMAD1	27
BP	GO:0090342	regulation of cell aging	27/7096	60/18670	0.1623	0.3735	0.2785	NAMPT/LMNA/ARG2/BCL6/MIF/KRAS/EEF1E1/VASH1/ZKSCAN3/PLK2/ABL1/HMGA1/SIRT1/HLA-G/YPEL3/MIR34A/BMPR1A/ZMPSTE24/KIR2DL4/WNT1/ARNTL/TERT/PNPT1/SLC30A10/NEK4/ZNF277/MIR146A	27
BP	GO:1902808	positive regulation of cell cycle G1/S phase transition	27/7096	60/18670	0.1623	0.3735	0.2785	ANXA1/CCND3/MEPCE/DDRGK1/RGCC/EZH2/LSM11/PAF1/CCND2/RDX/AIF1/CCND1/DDX3X/KMT2E/UBE2E2/CCNE1/ANKRD17/PLCB1/EGFR/ADAM17/MDM2/EIF4G1/MTBP/CUL4B/TERT/CDC73/STXBP4	27
BP	GO:2000117	negative regulation of cysteine-type endopeptidase activity	40/7096	92/18670	0.1644	0.3781	0.2819	KLF4/SERPINB9/CDKN2D/POR/PTGS2/SH3RF1/RPS6KA3/BIRC2/CD44/LAMP3/MICAL1/HGF/ARL6IP1/ARRB1/CAST/VEGFA/SFN/PAK2/RAF1/PLAUR/DNAJB6/DDX3X/CST7/FNIP1/MMP9/BIRC3/RFFL/BIRC7/LAMTOR5/CAAP1/MDM2/YWHAE/IGBP1/PCID2/MAP2K5/GPX1/TRIAP1/SNCA/XIAP/SIAH2	40
BP	GO:0014823	response to activity	29/7096	65/18670	0.1655	0.3803	0.2835	METRNL/GCLM/SRD5A1/FNDC5/PPARD/HADH/SLC25A25/ALAD/FIS1/HIF1A/LEP/COL4A2/CAT/GCLC/CREB1/PPARGC1A/OXCT1/MYOG/ITGA2/CYBA/GOT2/KDM6B/TOMM20/TPH2/PRKAA1/CAPN3/MTOR/HDAC5/MTFP1	29
BP	GO:0035308	negative regulation of protein dephosphorylation	29/7096	65/18670	0.1655	0.3803	0.2835	PPP1R15A/MGAT5/TNF/GSK3B/CABIN1/PHACTR2/PHACTR1/PPP1R26/SWAP70/PPP1R14A/ELFN1/PPP1R37/PPP1R2/PPP1R14B/PPP1R16B/MFHAS1/GNAI2/BOD1L1/ELFN2/PPP1R36/MYOZ1/PPP1R11/YWHAE/LMTK2/MASTL/PPP1R14D/SET/ROCK2/BOD1	29
BP	GO:0072665	protein localization to vacuole	29/7096	65/18670	0.1655	0.3803	0.2835	GBP1/NCOA4/TNFAIP3/LAMP2/VPS37B/VPS13A/M6PR/SH3BP4/NAGPA/GNPTAB/VPS37C/CLU/GOSR2/KPTN/VPS13D/LAMTOR4/NEDD4/HGS/VTI1A/LAMTOR5/VPS25/AP3B1/SH3GLB1/VTI1B/AP3M1/TRAPPC8/RTN4/SNX16/ROCK2	29
BP	GO:0007595	lactation	22/7096	48/18670	0.1659	0.3806	0.2837	VDR/USF2/HIF1A/ZBTB7B/VEGFA/STAT5A/OAS2/CREB1/ATP7B/CCND1/KALRN/MTX1/PAM/NME1/PPAT/GOT2/CAD/ATP7A/SOCS2/GJA1/APLN/CSN3	22
BP	GO:0010107	potassium ion import	22/7096	48/18670	0.1659	0.3806	0.2837	KCNJ5/KCNJ15/ATP1A1/ATP4A/SLC12A9/KCNJ1/ATP1B2/ATP1B3/SLC12A2/HCN4/SLC12A8/ATP1B1/KCNJ8/FXYD2/SLC12A1/SLC12A7/SLC12A4/KCNE2/ATP1A2/ATP12A/WNK2/SLC12A6	22
BP	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	22/7096	48/18670	0.1659	0.3806	0.2837	STAM/PTPN2/NUP62/DUSP3/CBLB/SOCS5/ZFYVE28/ZGPAT/RNF115/SNX6/RNF126/TSG101/HGS/GRB2/SPRY1/VPS25/EGFR/SPRY2/PSEN1/SNX5/HBEGF/PTPRJ	22
BP	GO:0045912	negative regulation of carbohydrate metabolic process	22/7096	48/18670	0.1659	0.3806	0.2837	CBFA2T3/FBP1/STAT3/SIK1/COX11/NUPR1/GSK3B/TGFB1/PPARGC1A/SLC25A12/MYOG/PFKFB1/INPP5K/HDAC4/PLEK/DDIT4/AP2A1/SERPINA12/MST1/PPARA/C1QTNF3/FAM3A	22
BP	GO:1903727	positive regulation of phospholipid metabolic process	22/7096	48/18670	0.1659	0.3806	0.2837	FPR2/HTR2B/NOD2/LYN/FLT1/CAPN2/ATG14/TGFB1/PTK2B/PRKCD/FLT3/FGR/P2RY12/FABP3/PDGFB/EPHA8/RAB38/PTK2/TAZ/CCL19/CCR7/NR1H4	22
BP	GO:0016180	snRNA processing	17/7096	36/18670	0.1662	0.3807	0.2838	INTS5/INTS7/TOE1/INTS9/USB1/INTS8/EXOSC2/INTS3/EXOSC7/INTS2/EXOSC9/EXOSC3/EXOSC6/EXOSC8/INTS4/INTS6/EXOSC5	17
BP	GO:0035872	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	17/7096	36/18670	0.1662	0.3807	0.2838	NOD2/TNFAIP3/BIRC2/UBE2N/NFKBIA/RELA/TAB3/TRAF6/IKBKG/TLR4/PTPN22/CASP8/CYLD/TAB1/BIRC3/UBC/XIAP	17
BP	GO:0071709	membrane assembly	17/7096	36/18670	0.1662	0.3807	0.2838	S100A10/PACSIN2/FLOT1/PSAP/EPHB2/SPTBN1/FLOT2/EMP2/UGCG/CAV3/ANXA2P2/DMKN/IL1RAPL1/ANXA2/LRP4/NLGN2/RFTN1	17
BP	GO:0090313	regulation of protein targeting to membrane	17/7096	36/18670	0.1662	0.3807	0.2838	ITGAM/FYN/CHP1/CIB1/C2CD5/MIEF1/FIS1/PAK1/CDK5/HRAS/GDI1/MYO1C/INPP5K/DMTN/CEMIP/CACNB3/ITGB1BP1	17
BP	GO:0021549	cerebellum development	44/7096	102/18670	0.1664	0.3807	0.2838	DLL1/NAGLU/MAP2K1/LDB1/EZH2/PAK1/HSPA5/CDK5/ABL1/OPHN1/AIF1/ATRN/SEMA4C/CRK/PPARGC1A/CLP1/ATIC/XRCC1/DAB1/HNRNPD/UQCRQ/LPAR1/CDK5R2/ARCN1/FZD4/WNT1/PSEN1/CBLN1/RORA/GNPAT/FAIM2/ATP7A/SPTBN2/KNDC1/ND4/TTBK2/LMX1A/TRNP1/WNT7A/CD3E/AGTPBP1/SMO/KIF14/CNTN1	44
BP	GO:0035335	peptidyl-tyrosine dephosphorylation	44/7096	102/18670	0.1664	0.3807	0.2838	PTPN6/DUSP1/DUSP6/DUSP5/PTPN2/EYA3/DUSP10/SSH2/PALD1/DUSP7/PTPRC/PTP4A1/PTPMT1/PTPRO/PTPN13/DUSP3/DUSP18/PTPN7/DUSP2/PTPN22/PTPN4/DUSP19/DUSP12/RNGTT/DUSP14/DNAJC6/DUSP4/DUSP23/MTMR4/MTMR6/CDC25A/MTMR2/PTPRN2/MTMR3/PTPDC1/EYA4/SSH3/PTPRH/DUSP13/SSH1/PTPRZ1/TIMM50/PTPRM/PTPRJ	44
BP	GO:1901568	fatty acid derivative metabolic process	70/7096	167/18670	0.1671	0.3807	0.2838	ALOX5/TLR2/ANXA1/ALOX5AP/CBR4/PTGS2/FAR2/HMGCL/MIF/ACOT7/PTGR1/ACSL5/MGST2/MGLL/CD74/ELOVL5/AKR1C3/PLAA/ZADH2/PTGR2/AACS/CYP1B1/SCD/HPGD/CYP2J2/ACSL4/ACLY/CYP2S1/IL1B/ACOX1/TECR/HSD17B4/CES2/GSTA1/ELOVL7/SIRT1/BDH1/GPX4/DGAT2/BDH2/PNPLA8/PTGES3/OXCT1/ACSL6/ALOX15B/DAGLB/PLA2G3/CYP2D6/CYP1A2/MAPKAPK2/HPGDS/FAR1/FABP5/GGT7/MGST3/GGTA1P/GGT5/GPX1/ELOVL6/ATP6V1B1/CYP4F3/ABCD1/ABHD16A/GGTLC1/HMGCLL1/CYP2A6/CYP2C8/PTGS1/HSD17B12/CYP2U1	70
BP	GO:0001503	ossification	161/7096	398/18670	0.1676	0.3807	0.2838	IGF1/SLC8A1/JUNB/CLEC5A/PTGER4/ACP5/VCAN/CLIC1/ACVR2B/SBNO2/SKI/RBPJ/DDX21/WNT5A/CHSY1/GPNMB/ATP6AP1/JUND/KLF10/MRC2/THRA/PTGS2/SPP1/SMAD5/TOB1/S1PR1/SNX10/ATRAID/LGR4/CEBPB/CBFB/DCHS1/CTSK/P2RX7/TNF/IFITM1/IMPAD1/EXT2/EXT1/ALYREF/THBS3/LRP5/ZHX3/DHRS3/SND1/TGFB1/HGF/GTPBP4/HIF1A/PTK2B/LEP/PDLIM7/ROR2/TRAF6/TCIRG1/CSGALNACT1/IFT80/RYR1/FZD9/FGR/TP53INP2/CEBPA/SNRNP200/BMP2/CAT/ITGA11/NAB1/LTBP3/SATB2/INTU/DHX9/XYLT1/TUFT1/SEMA4D/HSD17B4/ISG15/TNFRSF11A/TRPM4/IL6ST/BMP7/EGR2/IL6/BCOR/SPARC/PTK2/WWOX/TPM4/FBL/TMEM64/MYOG/BMP5/HDAC7/MYBBP1A/BMPR1A/HNRNPC/BCL2/BMP4/GFRA4/HDAC4/ID2/PRKACA/CLEC11A/ADRB2/ASGR2/MMP14/ZMPSTE24/SUCO/OSTF1/FZD1/SMOC1/MN1/EGFR/COL2A1/RRBP1/KL/SRGN/MAPK1/SHOX2/CTHRC1/CYP27B1/MINPP1/ERCC2/CLEC3A/TGFB3/SNAI1/ASF1A/BMP2K/PTHLH/MGP/TMEM38B/BCAP29/DSPP/MEN1/MMP2/PSMC2/RHOA/IBSP/ATP6V1B1/ADAR/NBR1/MMP16/KREMEN1/ZBTB16/LRP4/TMEM119/FGF23/WNT10B/CER1/GJA1/GREM1/INPPL1/BMPR1B/SMO/SYNCRIP/TWSG1/PTCH1/FIGNL1/KAZALD1/MEF2C/BMPR2/GDF5	161
BP	GO:0000041	transition metal ion transport	48/7096	112/18670	0.1676	0.3807	0.2838	ATP6V0D2/SLC40A1/SCO2/SLC11A1/MCOLN1/ATP6AP1/SLC25A37/STEAP4/ATP6V1C1/HFE/SLC31A2/ATP6V0C/SLC25A28/ATOX1/FTL/ISCU/STEAP3/TCIRG1/ATP6V1A/SLC39A10/ATP2C1/SLC39A8/ATP6V1G3/ATP7B/TRPM2/SLC39A13/SLC39A1/ATP6V1B2/SLC39A7/ATP6V1D/DNM2/ATP6V0E2/SFXN1/IREB2/ATP6V1G2/SLC30A6/SLC39A12/CUTC/TFRC/HAMP/TCN1/LMTK2/IFNG/ATP7A/SLC30A2/ATP6V1B1/SLC30A10/SLC30A9	48
BP	GO:0006354	DNA-templated transcription, elongation	48/7096	112/18670	0.1676	0.3807	0.2838	ELL2/ENY2/LDB1/EZH2/PAF1/ELP4/ERCC6/ALYREF/ZNF326/CCNH/ADRM1/GTF2F2/POLR2L/TAF1B/CTDP1/AFF4/ELL3/CDK9/POLR2H/SCAF8/GTF2H4/EAF1/ELP3/CCNK/TEFM/SUPT4H1/SSRP1/ZMYND11/TAF1D/GTF2F1/PBRM1/POLR1C/POLR2F/THOC5/POLR2D/LEO1/POLR2K/ELP2/ERCC2/NELFCD/TAF1C/PCID2/SUPT16H/TBP/CD3EAP/CCNT1/CDC73/POLR2I	48
BP	GO:0051153	regulation of striated muscle cell differentiation	50/7096	117/18670	0.1681	0.3807	0.2838	IGF1/TRIM32/DLL1/RBPJ/CAPN2/RGS2/SIK1/FLOT1/IL4R/CXCL9/MORF4L2/EZH2/AKAP13/CXCL10/CD53/TGFB1/PAK1/NRG1/FLT3LG/BMP2/PARP2/EHD1/CTDP1/G6PD/MESP1/NLN/MYOG/BCL2/BMP4/CYP26B1/NFATC2/HDAC4/YY1/MAMSTR/MMP14/LMOD3/PPARA/CAV3/KAT2A/HAMP/SHOX2/PIN1/FZD7/MSX1/MTOR/HDAC5/TMEM119/GREM1/MEF2C/MYF6	50
BP	GO:0023061	signal release	186/7096	462/18670	0.1681	0.3807	0.2838	CRHBP/APBA1/ANXA1/ACVR2B/LYN/STX11/RETN/RAP1B/SYT11/SPP1/PPARD/HADH/SIRT4/WLS/SMAD2/ENY2/PER2/CYB5R4/JAK2/FAM3D/P2RX7/CTBP2/HFE/KCNC4/TNF/GSK3B/HMGCR/DPP4/LRP5/PPP3CB/STXBP1/ITPR1/AACS/UNC13B/ARRB1/HIF1A/FFAR2/PIM3/ENHO/MYO5A/LEP/SYNJ1/PNKD/MCU/AIMP1/TCIRG1/FBXL20/ITSN1/CDK5/PAX8/RAB3GAP1/IL1B/DTNBP1/UQCC2/CCL5/C2CD2L/RAP1A/BLOC1S6/MPC2/LRP1/CREB1/RAF1/RFX3/IL1RN/TRPM4/DOC2B/RAC1/GLUD1/PREPL/IL6/KALRN/IRS2/SLC25A5/LRRK2/SYT6/KLF7/ADCY1/SERP1/SRI/OXCT1/PDZD11/P2RX1/ADORA2B/RPH3AL/VPS18/NAPA/GPR27/PPFIA4/RAB5A/SLC16A1/FFAR4/SYTL4/OSM/INHBA/CPT1A/PDX1/KDM5B/TM7SF3/PTPRN2/CAMK2A/PFKFB2/CHRM2/DNM1L/CHRNA4/HMGN3/RAB8B/EGFR/LIN7C/ICA1/NMB/ATP2A2/CLOCK/FZD4/DVL1/GIPR/PSEN1/FMR1/RAB3A/GALR1/CHRNB2/TCF7L2/EXOC3L1/P2RY4/PPFIA3/LTBP4/BAD/SYT9/PLA2G6/HNF1B/IFNG/HNF1A/ARNTL/VIP/NPVF/SNX19/SYT1/KIF5B/INHA/SNX4/REN/SYT2/VAMP1/STXBP3/DOC2A/SNAP29/SYT4/CADPS2/SNCAIP/NDUFAF2/MAP4K4/SYT5/SCG5/TRPV4/CHAT/BRSK1/GHRH/SNCA/KCNMB4/SLC9B2/SOX4/SIDT2/ARL2BP/RIMS2/GCG/WNT7A/PFKL/FGF23/NLGN2/GJA1/SYN3/NR1H4/TARDBP/STXBP4/PRKCA/UCN3/RBP4/PSMD9/C1QTNF3/P2RY1/TACR2/GHRL/MEF2C/KISS1/APLN/CCKAR/PHPT1	186
BP	GO:1905477	positive regulation of protein localization to membrane	52/7096	122/18670	0.1683	0.3807	0.2838	ITGAM/FYN/EZR/PLS1/ARF6/RAB11A/CHP1/PMAIP1/CIB1/YWHAH/SQSTM1/TNF/C2CD5/EPHB2/TGFB1/MIEF1/FIS1/PAK1/RHOG/CDK5/SFN/HRAS/CASP8/CNST/LRP1/SPTBN1/MYO1C/PDCD5/MAPK8/BCL2/GZMB/CNPY4/RANGRF/NKD2/YWHAQ/ITGA3/CEMIP/EGFR/STAC2/YWHAE/BAD/TREM2/IFNG/PPP1R13B/KIF5B/CACNB3/YWHAG/CLIP3/ITGB1BP1/SSH1/RER1/LRP4	52
BP	GO:1902904	negative regulation of supramolecular fiber organization	60/7096	142/18670	0.1685	0.3807	0.2838	MYADM/STMN1/ARAP1/S1PR1/CIB1/TMSB10/APOE/TMOD3/LIMA1/TWF2/RDX/PFN1/CAPZA2/SWAP70/PRKCD/GMFG/CORO1A/ARFGEF1/CAPG/LDLR/ARHGEF2/CAPZA1/MAPRE1/CLU/MKKS/ARPIN/SPTBN1/CDH5/CORO1B/ARHGAP6/BBS4/AVIL/INPP5K/KANK1/TRIOBP/ADD3/SHANK1/DMTN/CLASP2/LMOD3/CAV3/SCIN/SLIT2/TUBB4A/KATNB1/SPTA1/SPTBN2/TACSTD2/TMEFF2/KANK3/NAV3/PICK1/SNCA/CLIP3/TTBK2/IAPP/MET/FGF13/WAS/SHANK3	60
BP	GO:0006390	mitochondrial transcription	8/7096	15/18670	0.1688	0.3807	0.2838	MTERF1/MTERF2/CHCHD10/TEFM/SLC25A33/PRKAA1/POLRMT/FOXO3	8
BP	GO:0006491	N-glycan processing	8/7096	15/18670	0.1688	0.3807	0.2838	MAN1C1/MGAT4B/MAN2A2/GNPTAB/MAN1B1/GANAB/ST8SIA4/MAN1A2	8
BP	GO:0009209	pyrimidine ribonucleoside triphosphate biosynthetic process	8/7096	15/18670	0.1688	0.3807	0.2838	CTPS2/NME3/NME4/NME1/UCK1/CTPS1/CAD/UCKL1	8
BP	GO:0010561	negative regulation of glycoprotein biosynthetic process	8/7096	15/18670	0.1688	0.3807	0.2838	AGO2/ITM2B/ITM2A/BACE2/AATF/ABCA7/HBEGF/ACOT8	8
BP	GO:0015936	coenzyme A metabolic process	8/7096	15/18670	0.1688	0.3807	0.2838	PANK2/ACOT7/HMGCR/PANK3/PANK1/ACLY/NUDT7/CROT	8
BP	GO:0018216	peptidyl-arginine methylation	8/7096	15/18670	0.1688	0.3807	0.2838	PRMT9/NDUFAF7/PRDM4/PRMT5/COPRS/CARM1/PRMT1/NR1H4	8
BP	GO:0031054	pre-miRNA processing	8/7096	15/18670	0.1688	0.3807	0.2838	AGO2/BCDIN3D/MRPL44/DICER1/TARBP2/AGO1/DROSHA/ADAR	8
BP	GO:0032105	negative regulation of response to extracellular stimulus	8/7096	15/18670	0.1688	0.3807	0.2838	NUCB2/LEP/BBS2/MKKS/BBS4/PPARA/SPX/NENF	8
BP	GO:0032108	negative regulation of response to nutrient levels	8/7096	15/18670	0.1688	0.3807	0.2838	NUCB2/LEP/BBS2/MKKS/BBS4/PPARA/SPX/NENF	8
BP	GO:0032645	regulation of granulocyte macrophage colony-stimulating factor production	8/7096	15/18670	0.1688	0.3807	0.2838	DDX58/IL1B/RASGRP1/IL18/CD84/IL12B/CD80/IL23A	8
BP	GO:0033151	V(D)J recombination	8/7096	15/18670	0.1688	0.3807	0.2838	HMGB1/ATM/XRCC4/HMGB2/LIG4/BCL11B/DCLRE1C/POLB	8
BP	GO:0034349	glial cell apoptotic process	8/7096	15/18670	0.1688	0.3807	0.2838	DLL1/TNFRSF21/PRKCD/CDK5/CASP3/TRAF2/RB1/PRKCA	8
BP	GO:0034380	high-density lipoprotein particle assembly	8/7096	15/18670	0.1688	0.3807	0.2838	PRKACB/APOE/ABCA1/APOA5/LCAT/PRKACA/ABCA7/APOA1	8
BP	GO:0036445	neuronal stem cell division	8/7096	15/18670	0.1688	0.3807	0.2838	NUMB/ARHGEF2/ASPM/AKNA/DCT/NUMBL/SOX5/FGF13	8
BP	GO:0042362	fat-soluble vitamin biosynthetic process	8/7096	15/18670	0.1688	0.3807	0.2838	VDR/CYP27A1/TNF/NFKB1/IL1B/CYP27B1/SNAI1/IFNG	8
BP	GO:0042754	negative regulation of circadian rhythm	8/7096	15/18670	0.1688	0.3807	0.2838	CIPC/PER2/SUV39H2/SIN3A/SFPQ/SUV39H1/ADA/GHRL	8
BP	GO:0042976	activation of Janus kinase activity	8/7096	15/18670	0.1688	0.3807	0.2838	JAK2/PTK2B/CCL5/CD300A/SOCS1/IL12B/GHR/IL23A	8
BP	GO:0042983	amyloid precursor protein biosynthetic process	8/7096	15/18670	0.1688	0.3807	0.2838	AGO2/SOAT1/ITM2B/ITM2A/BACE2/AATF/ABCA7/NECAB3	8
BP	GO:0042984	regulation of amyloid precursor protein biosynthetic process	8/7096	15/18670	0.1688	0.3807	0.2838	AGO2/SOAT1/ITM2B/ITM2A/BACE2/AATF/ABCA7/NECAB3	8
BP	GO:0043249	erythrocyte maturation	8/7096	15/18670	0.1688	0.3807	0.2838	KLF2/FAM210B/ZBTB7A/G6PD/TAL1/ERCC2/EPB42/TRIM58	8
BP	GO:0043508	negative regulation of JUN kinase activity	8/7096	15/18670	0.1688	0.3807	0.2838	DUSP10/GSTP1/PTPN22/DUSP19/HIPK3/DNAJA1/PDCD4/AIDA	8
BP	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	8/7096	15/18670	0.1688	0.3807	0.2838	MIF/CD44/CD74/PTTG1IP/SIRT1/DYRK3/MDM2/SNAI1	8
BP	GO:0045342	MHC class II biosynthetic process	8/7096	15/18670	0.1688	0.3807	0.2838	SPI1/SLC11A1/AZU1/JAK2/TLR4/SIRT1/HDAC2/IFNG	8
BP	GO:0046851	negative regulation of bone remodeling	8/7096	15/18670	0.1688	0.3807	0.2838	CSK/TNFAIP3/P2RX7/IL6/CLDN18/IAPP/TMEM119/GREM1	8
BP	GO:0048172	regulation of short-term neuronal synaptic plasticity	8/7096	15/18670	0.1688	0.3807	0.2838	UNC13B/RAB3GAP1/SHISA9/SLC8A2/RAB3A/PPFIA3/SYT4/SHISA8	8
BP	GO:0050651	dermatan sulfate proteoglycan biosynthetic process	8/7096	15/18670	0.1688	0.3807	0.2838	VCAN/CSGALNACT1/CSPG4/CHST14/CSGALNACT2/BCAN/CHST12/B3GAT3	8
BP	GO:0055057	neuroblast division	8/7096	15/18670	0.1688	0.3807	0.2838	NUMB/ARHGEF2/ASPM/AKNA/DCT/NUMBL/SOX5/FGF13	8
BP	GO:0070571	negative regulation of neuron projection regeneration	8/7096	15/18670	0.1688	0.3807	0.2838	RTN4R/LRIG2/SPP1/CERS2/INPP5F/RTN4RL1/MAP4K4/KREMEN1	8
BP	GO:0071474	cellular hyperosmotic response	8/7096	15/18670	0.1688	0.3807	0.2838	AKR1B1/XRCC5/ARHGEF2/EFHD1/MICU1/YBX3/LETM1/XRCC6	8
BP	GO:0090136	epithelial cell-cell adhesion	8/7096	15/18670	0.1688	0.3807	0.2838	ITGB5/PLEKHA7/VCL/CYP1B1/CTNNA1/SRF/KIFC3/SERPINB8	8
BP	GO:1900029	positive regulation of ruffle assembly	8/7096	15/18670	0.1688	0.3807	0.2838	PFN1/HRAS/FAM98A/P2RY12/PLEKHM1/CYFIP1/NDEL1/EPS8L2	8
BP	GO:1902187	negative regulation of viral release from host cell	8/7096	15/18670	0.1688	0.3807	0.2838	TRIM32/TRIM13/TRIM26/PML/TRIM11/TRIM21/MID2/TRIM15	8
BP	GO:1902188	positive regulation of viral release from host cell	8/7096	15/18670	0.1688	0.3807	0.2838	VPS37B/CHMP4B/DDB1/CHMP2A/TSG101/VPS4B/SMC3/PC	8
BP	GO:0045661	regulation of myoblast differentiation	24/7096	53/18670	0.1705	0.3838	0.2861	DLL1/PPARD/KLHL41/CXCL9/TNF/CXCL10/TGFB1/SRA1/FLT3LG/HIF1AN/MBNL3/FLOT2/BTG1/MYOG/BMP4/NMRK2/MAP3K5/PLCB1/IL18/CAPN3/CMTM5/BOC/MEF2C/MYF6	24
BP	GO:0045840	positive regulation of mitotic nuclear division	24/7096	53/18670	0.1705	0.3838	0.2861	IGF1/NUP62/RGCC/LRP5/TGFB1/SMC5/INSR/UBXN2B/IL1B/NSMCE2/NSFL1C/PHIP/PDGFB/ESPL1/ANAPC5/SPHK1/IL1A/NUSAP1/UBE2C/DLGAP5/ANAPC4/RB1/AURKA/ANAPC11	24
BP	GO:0060563	neuroepithelial cell differentiation	24/7096	53/18670	0.1705	0.3838	0.2861	DLL1/RBPJ/SOD1/CEBPB/BMP2/ABL1/PAFAH1B1/B9D1/BCCIP/WDPCP/SERPINE1/DLX3/TRIOBP/HES1/HEY2/TMEM231/SLC4A7/POU4F3/DSPP/LRTOMT/SOX4/TMC1/MCOLN3/MYCL	24
BP	GO:0005979	regulation of glycogen biosynthetic process	14/7096	29/18670	0.171	0.3838	0.2861	IGF1/GSK3B/DYRK2/PPP1R3E/INSR/PPP1R3D/IRS2/INPP5K/PPP1R3B/PPP1R3F/PPP1CA/PPP1CB/ESRRB/MTOR	14
BP	GO:0008299	isoprenoid biosynthetic process	14/7096	29/18670	0.171	0.3838	0.2861	RBP1/RDH10/AKR1C3/HMGCR/DHRS9/HMGCS1/PDSS1/FDPS/IDI1/ALDH8A1/NUS1/DHDDS/SRD5A3/CRABP2	14
BP	GO:0010669	epithelial structure maintenance	14/7096	29/18670	0.171	0.3838	0.2861	NOD2/SLC22A5/LDB1/PBLD/ZNF830/SRF/PIWIL4/TLR4/MUC2/STRAP/MKS1/MUC6/LACRT/RBP4	14
BP	GO:0010800	positive regulation of peptidyl-threonine phosphorylation	14/7096	29/18670	0.171	0.3838	0.2861	WNT5A/AZU1/UBE2K/TGFB1/BMP7/CHI3L1/TNKS1BP1/SPHK1/PRKAG2/CEMIP/MAPK1/TRIM6/APP/GCG	14
BP	GO:0010962	regulation of glucan biosynthetic process	14/7096	29/18670	0.171	0.3838	0.2861	IGF1/GSK3B/DYRK2/PPP1R3E/INSR/PPP1R3D/IRS2/INPP5K/PPP1R3B/PPP1R3F/PPP1CA/PPP1CB/ESRRB/MTOR	14
BP	GO:0014044	Schwann cell development	14/7096	29/18670	0.171	0.3838	0.2861	MPP5/SKI/SOD1/LAMB2/NRG1/CDK5/NDRG1/DICER1/ADAM22/SH3TC2/LGI4/DAG1/NTRK2/POU3F1	14
BP	GO:0016577	histone demethylation	14/7096	29/18670	0.171	0.3838	0.2861	JMJD6/KDM1B/KDM7A/HSF4/KDM2A/KDM4B/KDM2B/KDM8/KDM5B/KDM6B/KDM4D/KDM5C/UBE2B/KDM4A	14
BP	GO:0035025	positive regulation of Rho protein signal transduction	14/7096	29/18670	0.171	0.3838	0.2861	RTN4R/P2RY8/AKAP13/ARRB1/RAC1/LPAR6/GPR18/LPAR1/F2R/GPR35/APOA1/SYNPO2L/P2RY10/GPR20	14
BP	GO:0042219	cellular modified amino acid catabolic process	14/7096	29/18670	0.171	0.3838	0.2861	PCYOX1/AHCY/ABHD12/ALDH4A1/PCYOX1L/BHMT/GOT2/GGT7/GGT5/ALDH1L1/CHAC2/ABHD16A/GGTLC1/DIO2	14
BP	GO:0044068	modulation by symbiont of host cellular process	14/7096	29/18670	0.171	0.3838	0.2861	SERPINB9/ATG7/GAPDH/KPNA4/CASP8/BCL2L11/CCL8/TNIP1/CCNK/KPNA1/BAD/CD4/EIF2AK4/KPNB1	14
BP	GO:1900181	negative regulation of protein localization to nucleus	14/7096	29/18670	0.171	0.3838	0.2861	CHP1/GSK3B/SIN3A/RAB23/CD36/LILRB4/MDFIC/MFHAS1/FLCN/DCLK2/FBXO4/TRIM29/CLDN18/PKIA	14
BP	GO:2000171	negative regulation of dendrite development	14/7096	29/18670	0.171	0.3838	0.2861	ARF6/DNM3/YWHAH/GSK3B/UBE3A/RAPGEF2/BCL11A/PLK2/SRGAP2C/DCC/HDAC2/FSTL4/CARM1/ASAP1	14
BP	GO:0033045	regulation of sister chromatid segregation	35/7096	80/18670	0.1721	0.386	0.2878	DUSP1/MAD2L2/DYNC1LI1/SPDL1/SMC5/CENPE/NAA10/RMI2/KLHL22/CDK5RAP2/NSMCE2/SFPQ/CDC23/ESPL1/ZNF207/LCMT1/ATM/ANAPC5/BUB3/NDC80/CTCF/GEN1/ZW10/MOS/CDC26/RIOK2/DLGAP5/ANAPC4/CDC27/CDC20/PCID2/RB1/ANAPC11/IK/FEN1	35
BP	GO:0046883	regulation of hormone secretion	109/7096	266/18670	0.1731	0.3866	0.2882	CRHBP/ANXA1/RETN/SPP1/PPARD/HADH/SIRT4/ENY2/PER2/JAK2/FAM3D/HFE/TNF/HMGCR/DPP4/LRP5/PPP3CB/ITPR1/AACS/ARRB1/HIF1A/FFAR2/PIM3/ENHO/LEP/MCU/AIMP1/TCIRG1/ITSN1/PAX8/IL1B/UQCC2/CCL5/C2CD2L/RAP1A/MPC2/LRP1/CREB1/RFX3/TRPM4/DOC2B/RAC1/GLUD1/KALRN/IRS2/SLC25A5/KLF7/SERP1/SRI/OXCT1/RPH3AL/GPR27/SLC16A1/SYTL4/OSM/INHBA/CPT1A/PDX1/KDM5B/TM7SF3/PFKFB2/HMGN3/RAB8B/EGFR/ICA1/NMB/CLOCK/GIPR/GALR1/TCF7L2/BAD/SYT9/PLA2G6/IFNG/ARNTL/VIP/NPVF/KIF5B/INHA/SNX4/REN/NDUFAF2/MAP4K4/SCG5/GHRH/SLC9B2/SOX4/SIDT2/ARL2BP/GCG/PFKL/FGF23/NLGN2/GJA1/NR1H4/TARDBP/STXBP4/PRKCA/UCN3/RBP4/PSMD9/C1QTNF3/P2RY1/TACR2/GHRL/KISS1/APLN/CCKAR/PHPT1	109
BP	GO:0000423	mitophagy	11/7096	22/18670	0.1732	0.3866	0.2882	PINK1/RNF41/ATG14/SQSTM1/CDC37/HTRA2/ATG13/VPS13D/USP30/CLEC16A/OPTN	11
BP	GO:0006379	mRNA cleavage	11/7096	22/18670	0.1732	0.3866	0.2882	PCF11/AGO2/MOV10/CSTF3/CPSF3/FIP1L1/CPSF2/ERN1/CPSF1/CPSF7/POLR2I	11
BP	GO:0008053	mitochondrial fusion	11/7096	22/18670	0.1732	0.3866	0.2882	VAT1/GDAP1/FIS1/OMA1/AFG3L2/BAX/USP30/DNM1L/MUL1/PID1/BAK1	11
BP	GO:0009220	pyrimidine ribonucleotide biosynthetic process	11/7096	22/18670	0.1732	0.3866	0.2882	UPP1/CTPS2/CMPK1/NME3/NME4/NME1/UCK1/CTPS1/CAD/UCKL1/UPP2	11
BP	GO:0010869	regulation of receptor biosynthetic process	11/7096	22/18670	0.1732	0.3866	0.2882	JAK2/HIF1A/HNRNPK/FURIN/HDAC2/SCAP/NR1H3/PPARA/IFNG/SEC24A/CNPY2	11
BP	GO:0016556	mRNA modification	11/7096	22/18670	0.1732	0.3866	0.2882	TRMT6/METTL14/METTL3/TRMT61B/PUS1/CBLL1/APOBEC2/CMTR1/CMTR2/TRMT10C/PUS7	11
BP	GO:0035584	calcium-mediated signaling using intracellular calcium source	11/7096	22/18670	0.1732	0.3866	0.2882	AZU1/PTPRC/DEFB1/BCAP31/FIS1/TRPM2/PRKACA/GPR143/DMTN/CCL20/PTPRJ	11
BP	GO:0045723	positive regulation of fatty acid biosynthetic process	11/7096	22/18670	0.1732	0.3866	0.2882	ANXA1/PTGS2/SLC45A3/CD74/ELOVL5/LPGAT1/NR1H2/IL1B/APOA5/NR1H3/ABCD1	11
BP	GO:0046628	positive regulation of insulin receptor signaling pathway	11/7096	22/18670	0.1732	0.3866	0.2882	ADIPOR1/GKAP1/PAK1/LEP/ZBTB7B/SIRT1/GNAI2/SERPINA12/PRKCZ/NUCKS1/NR1H4	11
BP	GO:0050765	negative regulation of phagocytosis	11/7096	22/18670	0.1732	0.3866	0.2882	TLR2/ATG3/CSK/SYT11/TGFB1/CD300LF/HMGB1/CD47/CD300A/PRTN3/APPL1	11
BP	GO:0090312	positive regulation of protein deacetylation	11/7096	22/18670	0.1732	0.3866	0.2882	PINK1/BCL6/TGFB1/ZBTB7B/VEGFA/LRRK2/AKAP8/PRKD2/IFNG/JDP2/BRMS1	11
BP	GO:0140112	extracellular vesicle biogenesis	11/7096	22/18670	0.1732	0.3866	0.2882	STAM/RAB11A/ARRDC4/SDCBP/CHMP2A/TSG101/HGS/VPS4B/IFNG/CD34/RAB27A	11
BP	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus	11/7096	22/18670	0.1732	0.3866	0.2882	RBPJ/SMAD5/ATF4/RELA/HIF1A/BMP2/VEGFA/CHD6/CREB3/NFE2L2/SESN2	11
BP	GO:0044743	protein transmembrane import into intracellular organelle	19/7096	41/18670	0.1734	0.3866	0.2882	TIMM23B/PEX12/PEX16/DNAJC19/TIMM17A/TIMM21/GRPEL1/GRPEL2/TOMM40L/PEX13/TOMM40/TOMM20/TIMM22/PEX14/AGK/DNAJC15/TIMM50/TIMM44/TIMM9	19
BP	GO:0070317	negative regulation of G0 to G1 transition	19/7096	41/18670	0.1734	0.3866	0.2882	CBX5/EZH2/RYBP/PCGF2/E2F6/RBBP7/MGA/RBBP4/HLA-G/CBX3/RRM2/FOXO4/RING1/BRCA1/EPC1/PHC1/PPP2R5B/YAF2/UXT	19
BP	GO:0098815	modulation of excitatory postsynaptic potential	19/7096	41/18670	0.1734	0.3866	0.2882	PTK2B/BAIAP2/LRRK2/SH3GL1/ADRB2/MTMR2/SHANK1/DVL1/CBLN1/CACNB3/PRKCZ/RELN/APP/SSH1/RIMS2/WNT7A/NLGN2/SHANK3/ZMYND8	19
BP	GO:0061951	establishment of protein localization to plasma membrane	26/7096	58/18670	0.1742	0.3883	0.2895	RILPL1/CSK/GGA2/RAB11A/VAMP5/SYS1/RAB31/GRIPAP1/GOPC/GORASP2/VAMP3/C16orf70/GRIP1/CNST/BBS2/RAB8A/PREPL/SPTBN1/GOLPH3L/GRASP/KIF13A/ARFRP1/LRRC7/OPTN/RAB26/MACF1	26
BP	GO:1904589	regulation of protein import	26/7096	58/18670	0.1742	0.3883	0.2895	NUP62/PTGS2/CHP1/FLNA/RAN/HCLS1/TGFB1/RAB23/CD36/LEP/PRKCD/HYAL2/ZPR1/UBR5/MDFIC/MAVS/NOLC1/PDCD5/BMP4/PSEN1/MAPK1/IFNG/CHP2/PKIA/SMO/TARDBP	26
BP	GO:0032886	regulation of microtubule-based process	90/7096	218/18670	0.1754	0.3907	0.2913	STMN1/MAP1S/NUP62/DIAPH1/CIB1/ATF5/LAMP1/SENP6/GSK3B/KAT2B/CHMP4B/TRIM37/PSRC1/PAK1/CLIP1/CEP131/CATSPER1/BICD2/STMN3/UBXN2B/PLK2/NPM1/ABL1/PAFAH1B1/CDK5RAP2/NSFL1C/ARHGEF2/CEP76/MAPRE1/SKA2/SPAG5/BBS2/CDK2AP2/MKKS/RAC1/MAPRE2/CDH5/CYLD/BICD1/BBS4/DIXDC1/SPICE1/PARP3/CHMP2A/MARK2/CDKN1B/RANGRF/GEN1/CHMP1A/VPS4B/CCDC65/SLC39A12/CLASP2/BRCA1/GPSM2/CAV3/TUBB4A/CHORDC1/MAP1A/KAT2A/PRKAA1/SMC3/KATNB1/IGBP1/RNF4/SLAIN2/PKHD1/STAG1/TRAF3IP1/CEP120/NAV3/RHOA/TRPV4/AURKA/SNCA/CLIP3/TTBK2/KLHL42/MET/FGF13/TRIM58/CHMP1B/ROCK2/TTLL6/CEP85/MACF1/ALMS1/CCNF/SKA3/TRIM46	90
BP	GO:1903076	regulation of protein localization to plasma membrane	41/7096	95/18670	0.1757	0.3912	0.2917	EZR/STX7/PLS1/ARF6/CSK/GBP1/RAB11A/CIB1/SQSTM1/TNF/EPHB2/ACTB/TGFB1/GRIPAP1/RHOG/GOPC/CDK5/NUMB/CNST/LRP1/SPTBN1/RHOQ/GRASP/CNPY4/RANGRF/NKD2/ITGA3/MMP14/EGFR/STAC2/PID1/VTI1B/TREM2/IFNG/STX8/KIF5B/AP2M1/CLIP3/RER1/PICALM/APPL1	41
BP	GO:0045637	regulation of myeloid cell differentiation	103/7096	251/18670	0.1761	0.392	0.2923	FOS/SIGLEC15/DLL1/SPI1/LYN/IRF7/ZFP36/NOTCH2/ATP6AP1/STAT3/PTPN2/KLF10/RNF41/LILRB3/KITLG/CIB1/FBXW7/STAT1/MYC/CEBPB/DPY30/CBFB/NFE2/LDB1/TNF/PAF1/CD74/NFKBIA/MOV10/TESC/LILRB1/KAT2B/HCLS1/FAM210B/EIF6/TGFB1/SIN3A/HIF1A/PTK2B/ROR2/LILRB4/TRAF6/TLR4/CASP8/GPR171/MITF/ISG15/CREB1/TYROBP/TFE3/KLF13/ACVR1B/TAL1/ETS1/KMT2E/TMEM64/HMGB2/ID2/NME1/CNOT4/AGO1/INHBA/TNRC6B/TNRC6A/EVI2B/RAB7B/ARNT/LEO1/PIAS3/FADD/SCIN/DCSTAMP/LRRC17/TREM2/C1QC/IFNG/NR4A3/CLDN18/CSF3R/CD4/RB1/TLR3/INHA/IL12B/MEIS1/KMT2B/MTOR/PRKCQ/FOXP1/CDC73/SLC9B2/ZBTB16/TRIM58/PRMT1/HOXA7/PRKCA/IL23A/WDR5/APCS/FOXO3/THPO/MEF2C/L3MBTL1	103
BP	GO:0001841	neural tube formation	45/7096	105/18670	0.177	0.3939	0.2936	VASP/BCL10/SKI/WNT5A/TSC1/TCTN1/IFT172/DVL2/PRKACB/IFT57/ZEB2/PLXNB2/MIB1/TGFB1/TULP3/PFN1/HIF1A/TRAF6/FUZ/CASP3/ABL1/SEMA4C/BMP7/IFT52/GLMN/BBS4/BMP5/BMP4/KDM2B/KIF20B/CFL1/PRKACA/SPINT1/MKS1/TEAD2/FZD1/DVL1/KAT2A/CTHRC1/PHACTR4/FZD2/SOX4/GRHL3/PTCH1/GRHL2	45
BP	GO:0006865	amino acid transport	61/7096	145/18670	0.1771	0.394	0.2937	APBA1/SLC43A2/SLC38A6/SLC11A1/SLC36A1/RGS2/SLC38A7/PER2/P2RX7/SLC7A11/STXBP1/CLN8/SLC7A7/UNC13B/ARL6IP1/LEP/SLC7A6/PRAF2/SLC7A5/SLC16A10/SLC1A4/RAB3GAP1/CLN3/SLC43A1/SLC25A15/LRRC8D/SLC38A1/SLC7A1/SLC25A12/SLC6A5/SLC7A8/PPFIA4/SFXN1/NFKBIE/GLS/SLC17A5/SLC36A4/NFE2L1/LRRC8A/SLC25A13/PSEN1/RAB3A/PPFIA3/SFXN5/SLC7A2/SYT1/SYT4/SLC6A13/SNCA/SLC25A22/OCA2/SFXN4/SLC25A38/SLC6A12/ATP1A2/LRRC8E/SLC38A5/CTNS/SLC38A9/NTSR1/NTRK2	61
BP	GO:0097553	calcium ion transmembrane import into cytosol	59/7096	140/18670	0.1774	0.3945	0.2941	SLC8A1/HTR2B/FYN/PTPN6/ATP2B4/LYN/MCOLN1/TPCN1/DIAPH1/CXCL9/CXCL11/PTPRC/P2RX7/CXCL10/PKD2/TGFB1/ITPR1/PTK2B/MYO5A/CORO1A/P2RY6/RYR1/ABL1/GSTO1/PLCG2/DMD/TRPM2/LCK/CCR5/SRI/RASA3/BAX/PRKACA/CYBA/MCOLN2/F2R/GRIN2C/CAMK2D/PLCB1/CEMIP/LETM1/CASQ1/CAPN3/CASQ2/HRC/BDKRB1/TMEM38B/LACRT/LIME1/SNCA/CX3CL1/CCL19/CHERP/ATP1A2/CCR7/SLC8A3/MCOLN3/FAM155A/NTSR1	59
BP	GO:1903825	organic acid transmembrane transport	57/7096	135/18670	0.1776	0.3946	0.2942	SLC43A2/SLC38A6/AQP9/SLC36A1/SLC23A2/RGS2/SLC25A20/SLC38A7/FOLR2/PER2/SLC7A11/CPT2/CLN8/SLC7A7/ARL6IP1/SLC7A6/PRAF2/SLC7A5/SLC16A10/SLC1A4/SLC25A10/MPC2/ACACB/SLC35D1/SLC43A1/SLC25A15/LRRC8D/IRS2/SLC38A1/SLC7A1/SLC25A12/PRKAG2/SLC6A5/SLC7A8/SLC16A1/SLC46A1/CPT1A/SLC5A6/SLC16A7/SLC36A4/LRRC8A/SLC25A13/SLC5A8/PSEN1/SLC7A2/SLC25A22/SLC25A32/SLC25A38/SLC6A12/ATP1A2/LRRC8E/SLC38A5/THRSP/SLC35D2/SLC38A9/NTSR1/STRA6	57
BP	GO:1905039	carboxylic acid transmembrane transport	57/7096	135/18670	0.1776	0.3946	0.2942	SLC43A2/SLC38A6/AQP9/SLC36A1/SLC23A2/RGS2/SLC25A20/SLC38A7/FOLR2/PER2/SLC7A11/CPT2/CLN8/SLC7A7/ARL6IP1/SLC7A6/PRAF2/SLC7A5/SLC16A10/SLC1A4/SLC25A10/MPC2/ACACB/SLC35D1/SLC43A1/SLC25A15/LRRC8D/IRS2/SLC38A1/SLC7A1/SLC25A12/PRKAG2/SLC6A5/SLC7A8/SLC16A1/SLC46A1/CPT1A/SLC5A6/SLC16A7/SLC36A4/LRRC8A/SLC25A13/SLC5A8/PSEN1/SLC7A2/SLC25A22/SLC25A32/SLC25A38/SLC6A12/ATP1A2/LRRC8E/SLC38A5/THRSP/SLC35D2/SLC38A9/NTSR1/STRA6	57
BP	GO:0043062	extracellular structure organization	170/7096	422/18670	0.1776	0.3946	0.2942	ITGAM/FN1/ICAM2/STAM/ADAMTSL4/COL23A1/VCAN/ICAM3/ITGA5/ITGB7/CAPN2/ITGB5/SPP1/TIMP2/CTSS/LAMB2/FLOT1/CD44/ADAM19/F11R/APOC1/SCARB1/RGCC/PLA2G7/CTSK/SOAT1/A2M/ADAM8/TNF/PRKACB/SH3PXD2A/MPV17/CETP/APOE/CST3/DPP4/KIF9/ITGAD/TGFB1/CYP1B1/COL8A2/CD36/LAMC3/ITGAL/COL4A2/ADAM15/NFKB2/PTX3/ITGA4/LOXL2/CSGALNACT1/ITGA7/LAMB3/QSOX1/CRISPLD2/ABL1/ITGA11/ABCA1/FURIN/SDCBP/MMP12/CAPNS2/LRP1/BMP7/TPSAB1/IL6/ABCA5/PDGFB/PLOD1/ITGAE/DNAJB6/APOA5/SULF2/SPARC/PTK2/ICAM4/ETS1/ARF1/KLK4/LCP1/LCAT/MMP9/ADAMTS2/SERPINE1/ADAM12/CD47/COL7A1/TIMP1/TSG101/ABCG1/PRKACA/MMP3/PLOD2/MADCAM1/SPINT1/VIPAS39/ITGA2/HTRA1/CTRB2/SPOCK2/CTSV/MMP1/PDGFA/BCAN/VWF/ITGA3/MMP14/ABCA7/POMT1/CLASP2/COL2A1/JAM3/ANXA2P2/CMA1/ATXN1L/FSCN1/LAMA2/EFEMP2/APOA1/ERCC2/COL4A3/TNXB/ITGA8/COL15A1/ATP7A/CD34/COL6A3/TMEM38B/RB1/DSPP/CTSG/THSD4/FOXF2/NID1/MMP2/NR2E1/COL18A1/COL11A2/SERAC1/TGFBI/ANXA2/HPN/MMP27/APP/MMP10/DAG1/IBSP/B4GALT1/MFAP2/ENG/HAPLN1/MMP16/FOXF1/MPO/GREM1/P4HA1/MMP19/AEBP1/WT1/ADAMTS4/SERPINF2/TLL2/SCUBE3/CAPNS1/PRSS2/HSD17B12/ADAMTS9/ALB/KAZALD1/LAMA1	170
BP	GO:0045471	response to ethanol	53/7096	125/18670	0.1778	0.3949	0.2944	CRHBP/NQO1/S100A8/FYN/KCNMB1/SPI1/SOD1/STAT3/BIRC2/RGS2/GSTP1/HMGCR/ACTR2/AACS/ALAD/HPGD/PTK2B/LEP/ACTC1/USP46/CAT/CASP8/CCL7/RGS19/CCND1/SETD7/ADCY7/G6PD/SPARC/OXCT1/HDAC2/SETDB1/TYMS/CYBB/GOT2/DNMT3A/MAOB/PRKAA1/HAMP/CHRNB2/BAD/CLDN18/DBH/POLB/ND4/RHOA/BAK1/MGMT/ADH7/ADCYAP1R1/RBP4/HTR3A/RPL10A	53
BP	GO:0033047	regulation of mitotic sister chromatid segregation	30/7096	68/18670	0.1797	0.3988	0.2973	DUSP1/MAD2L2/DYNC1LI1/SPDL1/SMC5/CENPE/NAA10/KLHL22/CDK5RAP2/NSMCE2/CDC23/ESPL1/ZNF207/LCMT1/ATM/ANAPC5/BUB3/NDC80/GEN1/ZW10/CDC26/RIOK2/DLGAP5/ANAPC4/CDC27/CDC20/PCID2/RB1/ANAPC11/IK	30
BP	GO:0045806	negative regulation of endocytosis	30/7096	68/18670	0.1797	0.3988	0.2973	TLR2/ARF6/ATG3/CSK/SYT11/PACSIN2/APOC1/LILRB1/TGFB1/NR1H2/LRPAP1/SDCBP/CD300LF/HMGB1/RAC1/SNX33/ATXN2/UBQLN2/CD47/NR1H3/MTMR2/CD300A/RABGEF1/ABCA7/ANKRD13D/PRTN3/SCAMP5/PICALM/APPL1/PACSIN3	30
BP	GO:0050918	positive chemotaxis	30/7096	68/18670	0.1797	0.3988	0.2973	FPR2/WNT5A/AZU1/GPNMB/VEGFB/S1PR1/ALKBH1/MIF/CXCL10/CXCL12/HGF/ROBO3/CORO1A/VEGFA/AGER/CCL5/LRP1/HMGB1/PDGFB/IL16/NRP1/BMP4/HMGB2/ITGA2/CCR4/SEMA5A/F3/CX3CL1/MET/PTPRJ	30
BP	GO:0007094	mitotic spindle assembly checkpoint	16/7096	34/18670	0.1804	0.3994	0.2977	DUSP1/MAD2L2/DYNC1LI1/SPDL1/KLHL22/CDK5RAP2/ZNF207/LCMT1/ATM/BUB3/NDC80/GEN1/ZW10/CDC20/PCID2/IK	16
BP	GO:0031577	spindle checkpoint	16/7096	34/18670	0.1804	0.3994	0.2977	DUSP1/MAD2L2/DYNC1LI1/SPDL1/KLHL22/CDK5RAP2/ZNF207/LCMT1/ATM/BUB3/NDC80/GEN1/ZW10/CDC20/PCID2/IK	16
BP	GO:0032148	activation of protein kinase B activity	16/7096	34/18670	0.1804	0.3994	0.2977	IGF1/PINK1/WNT5A/PRR5/INSR/NRG1/CCDC88A/MLST8/PDGFB/FGF1/TXN/IL18/MAPKAP1/PRKCZ/MTOR/ITGB1BP1	16
BP	GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator	16/7096	34/18670	0.1804	0.3994	0.2977	PMAIP1/MIF/CD44/CD74/EEF1E1/PTTG1IP/SIRT1/ATM/ZMPSTE24/SPRED1/DYRK3/ATR/MDM2/SNAI1/MSX1/HIC1	16
BP	GO:0070670	response to interleukin-4	16/7096	34/18670	0.1804	0.3994	0.2977	IL2RG/NFIL3/STAT6/PTPN2/KEAP1/MCM2/IL4R/CDK4/ALAD/CORO1A/HSPA5/CD300LF/PML/DCSTAMP/TUBA1B/HSP90AB1	16
BP	GO:0071173	spindle assembly checkpoint	16/7096	34/18670	0.1804	0.3994	0.2977	DUSP1/MAD2L2/DYNC1LI1/SPDL1/KLHL22/CDK5RAP2/ZNF207/LCMT1/ATM/BUB3/NDC80/GEN1/ZW10/CDC20/PCID2/IK	16
BP	GO:0071174	mitotic spindle checkpoint	16/7096	34/18670	0.1804	0.3994	0.2977	DUSP1/MAD2L2/DYNC1LI1/SPDL1/KLHL22/CDK5RAP2/ZNF207/LCMT1/ATM/BUB3/NDC80/GEN1/ZW10/CDC20/PCID2/IK	16
BP	GO:0000281	mitotic cytokinesis	32/7096	73/18670	0.1818	0.4019	0.2996	KLHDC8B/ZFYVE26/STMN1/NUP62/RHOC/CHMP4B/SNX18/JTB/KIF4A/SPTBN1/SNX33/ESPL1/BBS4/ARF1/CEP55/CHMP2A/KIF20B/CFL1/NUSAP1/INCENP/CHMP1A/VPS4B/BIN3/RAB35/STAMBP/CENPA/RHOA/SNX9/EFHC1/CHMP1B/ROCK2/SON	32
BP	GO:0044766	multi-organism transport	32/7096	73/18670	0.1818	0.4019	0.2996	NUP62/NMT2/NUP160/NUP214/VPS37B/RAN/ALYREF/NUP85/SEH1L/NUP43/CD209/VPS37C/POM121/RAB29/NUP88/THOC2/TSG101/NUP107/UBAP1/UBC/IFIT1/THOC5/NUP93/THOC6/NUP205/FMR1/KPNA1/NUP50/TRIM15/KPNB1/POM121C/AAAS	32
BP	GO:1902579	multi-organism localization	32/7096	73/18670	0.1818	0.4019	0.2996	NUP62/NMT2/NUP160/NUP214/VPS37B/RAN/ALYREF/NUP85/SEH1L/NUP43/CD209/VPS37C/POM121/RAB29/NUP88/THOC2/TSG101/NUP107/UBAP1/UBC/IFIT1/THOC5/NUP93/THOC6/NUP205/FMR1/KPNA1/NUP50/TRIM15/KPNB1/POM121C/AAAS	32
BP	GO:0090090	negative regulation of canonical Wnt signaling pathway	74/7096	178/18670	0.1819	0.402	0.2997	MAD2L2/WNT5A/PSMB9/KLHL12/PSMB8/EGR1/PSMA5/DVL2/PSMD11/APOE/GSK3B/PSME1/PTPRO/PSMB10/IGFBP4/TLE1/PSMA1/MCC/PSMA4/ROR2/LATS1/RUVBL2/FUZ/BMP2/TLE4/PSMB1/EMD/PSMC4/SFRP4/PSMD13/IGFBP2/PSMB3/TMEM170B/CYLD/MESP1/PSMB5/PSMD6/CSNK1A1/PSMC3/TMEM64/NPHP4/PSME3/PSMC6/TLE6/TMEM88/NKD2/FZD1/DKK2/DVL1/TCF7L2/CTHRC1/PSMC1/PSMD8/PSMA2/LATS2/ANKRD6/JADE1/PFDN5/PSMC5/PSMC2/PSMB2/PSMD4/RBX1/SDHAF2/KREMEN1/LRP4/PSMD1/SFRP5/PSMB4/GREM1/PSMD9/PSMD3/SIAH2/FOXO3	74
BP	GO:0015849	organic acid transport	135/7096	333/18670	0.1828	0.4033	0.3006	SLC27A1/APBA1/SLC43A2/ANXA1/SLC19A2/PLA2G12A/SLC27A3/SLC38A6/FABP4/AQP9/SLC11A1/SLC36A1/SLC23A2/SLCO3A1/PPARD/MIF/RGS2/SLC25A20/SLC38A7/PLIN2/FOLR2/PER2/PSAP/P2RX7/SLC7A11/APOE/SLCO2B1/CPT2/STXBP1/CLN8/SLC7A7/UNC13B/ARL6IP1/STARD10/ABCD3/CD36/LEP/SLC7A6/PRAF2/SLC7A5/SLC16A10/ACSL4/AKR1C1/SLC1A4/RAB3GAP1/IL1B/CLN3/SLC25A10/SLC27A2/MPC2/ACACB/SLC35D1/ATP8B1/TNFRSF11A/SLC43A1/SLC25A15/LRRC8D/FABP3/IRS2/SLC38A1/PNPLA8/SLC7A1/SLC16A6/SLC25A12/MFSD2A/SLC26A8/PLA2G3/PRKAG2/NCOR1/NMUR2/RXRA/SLC6A5/SLC7A8/PPFIA4/SLC16A2/SLC16A1/SFXN1/SLC46A1/CPT1A/ABCB4/SLC10A1/SLC5A6/ABCB11/NFKBIE/SLC13A2/GLS/GOT2/SLC17A5/SLC26A4/SLC16A7/SLC36A4/NFE2L1/LRRC8A/PPARA/SLC25A13/NMB/SLC5A8/SLC35A5/PSEN1/SLC17A4/RAB3A/PPFIA3/SFXN5/PLA2G6/SLC7A2/SYT1/ABCC3/ABCC4/CROT/SYT4/SLC6A13/SLCO1C1/SNCA/SLC25A22/SLC25A32/OCA2/ABCD1/SFXN4/SLC25A38/SLC26A10/SLC6A12/ATP1A2/SPX/LRRC8E/SLC38A5/CTNS/THRSP/SLC35D2/NR1H4/SLC38A9/NTSR1/NTRK2/SLCO1B1/SLC16A5/STRA6	135
BP	GO:0046942	carboxylic acid transport	135/7096	333/18670	0.1828	0.4033	0.3006	SLC27A1/APBA1/SLC43A2/ANXA1/SLC19A2/PLA2G12A/SLC27A3/SLC38A6/FABP4/AQP9/SLC11A1/SLC36A1/SLC23A2/SLCO3A1/PPARD/MIF/RGS2/SLC25A20/SLC38A7/PLIN2/FOLR2/PER2/PSAP/P2RX7/SLC7A11/APOE/SLCO2B1/CPT2/STXBP1/CLN8/SLC7A7/UNC13B/ARL6IP1/STARD10/ABCD3/CD36/LEP/SLC7A6/PRAF2/SLC7A5/SLC16A10/ACSL4/AKR1C1/SLC1A4/RAB3GAP1/IL1B/CLN3/SLC25A10/SLC27A2/MPC2/ACACB/SLC35D1/ATP8B1/TNFRSF11A/SLC43A1/SLC25A15/LRRC8D/FABP3/IRS2/SLC38A1/PNPLA8/SLC7A1/SLC16A6/SLC25A12/MFSD2A/SLC26A8/PLA2G3/PRKAG2/NCOR1/NMUR2/RXRA/SLC6A5/SLC7A8/PPFIA4/SLC16A2/SLC16A1/SFXN1/SLC46A1/CPT1A/ABCB4/SLC10A1/SLC5A6/ABCB11/NFKBIE/SLC13A2/GLS/GOT2/SLC17A5/SLC26A4/SLC16A7/SLC36A4/NFE2L1/LRRC8A/PPARA/SLC25A13/NMB/SLC5A8/SLC35A5/PSEN1/SLC17A4/RAB3A/PPFIA3/SFXN5/PLA2G6/SLC7A2/SYT1/ABCC3/ABCC4/CROT/SYT4/SLC6A13/SLCO1C1/SNCA/SLC25A22/SLC25A32/OCA2/ABCD1/SFXN4/SLC25A38/SLC26A10/SLC6A12/ATP1A2/SPX/LRRC8E/SLC38A5/CTNS/THRSP/SLC35D2/NR1H4/SLC38A9/NTSR1/NTRK2/SLCO1B1/SLC16A5/STRA6	135
BP	GO:0050806	positive regulation of synaptic transmission	70/7096	168/18670	0.1833	0.4033	0.3006	NRGN/CCR2/CX3CR1/LILRB2/PINK1/RETN/PTGS2/FLOT1/LGMN/SQSTM1/TNF/EPHB2/APOE/GSK3B/TSHZ3/STXBP1/UNC13B/PTK2B/ROR2/STAU1/BAIAP2/CDK5/PLK2/ABL1/RAB3GAP1/DTNBP1/S100B/AGER/CREB1/TYROBP/NPTN/ARC/CRTC1/ADCY1/RGS14/ADRB2/SHANK1/GRIN2C/DNM1L/EGFR/DVL1/SLC8A2/LAMA2/FMR1/MAPK1/CHRNB2/SYT9/SYT1/KIF5B/RAB3B/CACNB3/EIF2AK4/NR2E1/PRKCZ/RELN/APP/SNCA/SLC24A2/SSH1/RIMS2/WNT7A/SLC8A3/CYP46A1/NLGN2/CLSTN3/SHANK3/TACR2/NTSR1/NTRK2/KISS1	70
BP	GO:0008589	regulation of smoothened signaling pathway	34/7096	78/18670	0.1834	0.4033	0.3006	POR/CHSY1/DISP1/TCTN1/EVC/IFT172/PRKACB/PDCL/TULP3/CTNNA1/MEGF8/WDR11/FUZ/PTCH2/INTU/TUBD1/GORAB/KCTD11/PRKACA/MKS1/SHOX2/RORA/RB1/GPR161/TRAF3IP1/FBXL17/CD3E/SMO/KCTD21/IFT81/PTCH1/C2CD3/SCUBE3/GAS8	34
BP	GO:0032206	positive regulation of telomere maintenance	23/7096	51/18670	0.1835	0.4033	0.3006	MAP3K4/PKIB/NAF1/HNRNPA1/HNRNPA2B1/XRCC5/PML/ATM/MAPKAPK5/ERCC1/HNRNPD/CCT4/FBXO4/CCT8/ATR/MAPK1/RTEL1/ACD/PRKCQ/POT1/GNL3/PNKP/NEK7	23
BP	GO:0050999	regulation of nitric-oxide synthase activity	23/7096	51/18670	0.1835	0.4033	0.3006	HTR2B/ATP2B4/GCH1/SCARB1/TNF/DDAH2/KRAS/APOE/HIF1A/PTK2B/LEP/IL1B/GLA/SPR/FCER2/DNM2/CNR2/DHFR/EGFR/CAV3/NUS1/TERT/ZDHHC21	23
BP	GO:0000722	telomere maintenance via recombination	7/7096	13/18670	0.1854	0.4033	0.3006	ERCC4/SMC5/SMC6/TEP1/NSMCE2/XRCC1/ERCC1	7
BP	GO:0001833	inner cell mass cell proliferation	7/7096	13/18670	0.1854	0.4033	0.3006	GINS1/ZPR1/PALB2/NDEL1/COPS2/GINS4/PRPF19	7
BP	GO:0001973	adenosine receptor signaling pathway	7/7096	13/18670	0.1854	0.4033	0.3006	ACPP/P2RY12/ADORA2B/GNAI2/ADA/ADORA3/P2RY1	7
BP	GO:0002430	complement receptor mediated signaling pathway	7/7096	13/18670	0.1854	0.4033	0.3006	FPR2/FPR1/CMKLR1/CR1/C3AR1/CR2/C5AR2	7
BP	GO:0009143	nucleoside triphosphate catabolic process	7/7096	13/18670	0.1854	0.4033	0.3006	SMPDL3A/NUDT1/SAMHD1/ADA/DCTPP1/DUT/NUDT16	7
BP	GO:0009437	carnitine metabolic process	7/7096	13/18670	0.1854	0.4033	0.3006	SLC22A4/POR/ALDH9A1/ACADM/CPT1A/SHMT1/CROT	7
BP	GO:0010872	regulation of cholesterol esterification	7/7096	13/18670	0.1854	0.4033	0.3006	STARD4/APOC1/APOE/LAMTOR1/APOA5/ABCG1/APOA1	7
BP	GO:0021681	cerebellar granular layer development	7/7096	13/18670	0.1854	0.4033	0.3006	OPHN1/CBLN1/FAIM2/KNDC1/TTBK2/WNT7A/KIF14	7
BP	GO:0031650	regulation of heat generation	7/7096	13/18670	0.1854	0.4033	0.3006	SLC27A1/PTGS2/TNF/ARRDC3/IL1B/TNFRSF11A/APLN	7
BP	GO:0031953	negative regulation of protein autophosphorylation	7/7096	13/18670	0.1854	0.4033	0.3006	CHP1/NLRP12/PTPRC/MVP/GFRA2/IMPACT/ENG	7
BP	GO:0032530	regulation of microvillus organization	7/7096	13/18670	0.1854	0.4033	0.3006	EZR/PLS1/PLD1/TWF2/ATP8B1/KLF5/FSCN1	7
BP	GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production	7/7096	13/18670	0.1854	0.4033	0.3006	DDX58/IL1B/RASGRP1/IL18/IL12B/CD80/IL23A	7
BP	GO:0032823	regulation of natural killer cell differentiation	7/7096	13/18670	0.1854	0.4033	0.3006	IL15/AXL/ZBTB1/FLT3LG/RASGRP1/TOX/PGLYRP4	7
BP	GO:0034969	histone arginine methylation	7/7096	13/18670	0.1854	0.4033	0.3006	PRMT9/PRDM4/PRMT5/COPRS/CARM1/PRMT1/NR1H4	7
BP	GO:0038007	netrin-activated signaling pathway	7/7096	13/18670	0.1854	0.4033	0.3006	SIAH1/TUBB3/DCC/PTK2/UNC5B/UNC5C/SIAH2	7
BP	GO:0042178	xenobiotic catabolic process	7/7096	13/18670	0.1854	0.4033	0.3006	ACAA1/GSTP1/GSTO1/GSTM3/GSTM5/GSTM4/CRYZ	7
BP	GO:0042538	hyperosmotic salinity response	7/7096	13/18670	0.1854	0.4033	0.3006	AKR1B1/XRCC5/EFHD1/MICU1/LETM1/XRCC6/TRPV4	7
BP	GO:0042635	positive regulation of hair cycle	7/7096	13/18670	0.1854	0.4033	0.3006	WNT5A/TNF/TRADD/HPSE/TERT/FOXN1/WNT10B	7
BP	GO:0043247	telomere maintenance in response to DNA damage	7/7096	13/18670	0.1854	0.4033	0.3006	ERCC4/XRCC1/ERCC1/DCLRE1A/RTEL1/ACD/DCLRE1C	7
BP	GO:0045759	negative regulation of action potential	7/7096	13/18670	0.1854	0.4033	0.3006	KCNE3/SUMO1/CNR2/CAV3/GPR35/CHRNB2/BIN1	7
BP	GO:0045779	negative regulation of bone resorption	7/7096	13/18670	0.1854	0.4033	0.3006	CSK/TNFAIP3/P2RX7/IL6/CLDN18/IAPP/TMEM119	7
BP	GO:0048291	isotype switching to IgG isotypes	7/7096	13/18670	0.1854	0.4033	0.3006	IL27RA/CD40/PTPRC/MLH1/TBX21/PAXIP1/ATAD5	7
BP	GO:0048681	negative regulation of axon regeneration	7/7096	13/18670	0.1854	0.4033	0.3006	RTN4R/LRIG2/SPP1/CERS2/INPP5F/RTN4RL1/KREMEN1	7
BP	GO:0050722	regulation of interleukin-1 beta biosynthetic process	7/7096	13/18670	0.1854	0.4033	0.3006	AZU1/JAK2/EGR1/AGER/TYROBP/IFNG/APP	7
BP	GO:0051451	myoblast migration	7/7096	13/18670	0.1854	0.4033	0.3006	ANXA1/PLEKHO1/NET1/BIN3/MEGF10/ITGB1BP1/SMO	7
BP	GO:0061000	negative regulation of dendritic spine development	7/7096	13/18670	0.1854	0.4033	0.3006	DNM3/UBE3A/PLK2/SRGAP2C/HDAC2/FSTL4/ASAP1	7
BP	GO:0061042	vascular wound healing	7/7096	13/18670	0.1854	0.4033	0.3006	TNFAIP3/MIR34A/HPSE/SERPINE1/ADIPOR2/CD34/MCAM	7
BP	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development	7/7096	13/18670	0.1854	0.4033	0.3006	RGS2/PAK1/CTDP1/G6PD/YY1/PPARA/CAV3	7
BP	GO:0070986	left/right axis specification	7/7096	13/18670	0.1854	0.4033	0.3006	DLL1/SETDB2/IFT172/ARL13B/CITED2/HSPB11/SMO	7
BP	GO:0071352	cellular response to interleukin-2	7/7096	13/18670	0.1854	0.4033	0.3006	IL2RG/PTPN2/PTK2B/IL2RB/STAT5A/SHC1/JAK1	7
BP	GO:0071872	cellular response to epinephrine stimulus	7/7096	13/18670	0.1854	0.4033	0.3006	ATP2B4/SRD5A1/SLC9A1/PDE4B/PRKACA/KCNQ1/SNCA	7
BP	GO:0072672	neutrophil extravasation	7/7096	13/18670	0.1854	0.4033	0.3006	ADAM8/CD99/IL1R1/CD99L2/PIK3CD/PIK3CG/PRTN3	7
BP	GO:0090239	regulation of histone H4 acetylation	7/7096	13/18670	0.1854	0.4033	0.3006	SPI1/ARRB1/KAT7/SIRT1/MUC1/ZMPSTE24/BRCA1	7
BP	GO:0090481	pyrimidine nucleotide-sugar transmembrane transport	7/7096	13/18670	0.1854	0.4033	0.3006	SLC35B4/SLC35D1/SLC35B1/SLC35A3/SLC35A5/SLC35A2/SLC35D2	7
BP	GO:0097152	mesenchymal cell apoptotic process	7/7096	13/18670	0.1854	0.4033	0.3006	ETV6/HIF1A/PAX8/BMP7/HNF1B/MSX1/GDF5	7
BP	GO:0098712	L-glutamate import across plasma membrane	7/7096	13/18670	0.1854	0.4033	0.3006	PER2/SLC7A11/CLN8/ARL6IP1/PSEN1/ATP1A2/NTSR1	7
BP	GO:0099633	protein localization to postsynaptic specialization membrane	7/7096	13/18670	0.1854	0.4033	0.3006	HRAS/RAP1A/ADAM22/IQSEC2/PRKCZ/GPC4/DAG1	7
BP	GO:0099645	neurotransmitter receptor localization to postsynaptic specialization membrane	7/7096	13/18670	0.1854	0.4033	0.3006	HRAS/RAP1A/ADAM22/IQSEC2/PRKCZ/GPC4/DAG1	7
BP	GO:1902713	regulation of interferon-gamma secretion	7/7096	13/18670	0.1854	0.4033	0.3006	CD2/PTPN22/ABL1/RASGRP1/LGALS9/CD244/NR1H4	7
BP	GO:2000009	negative regulation of protein localization to cell surface	7/7096	13/18670	0.1854	0.4033	0.3006	ARF6/GOPC/SNX33/COMMD1/CAV3/ASTN2/PICALM	7
BP	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining	7/7096	13/18670	0.1854	0.4033	0.3006	MAD2L2/PARP9/SETMAR/SMCHD1/DTX3L/PARP3/KDM4D	7
BP	GO:0061041	regulation of wound healing	62/7096	148/18670	0.1857	0.4039	0.3011	SERPINB2/ANXA1/CDKN1A/CLEC7A/LYN/PROS1/PPARD/TFPI/DUSP10/TNFAIP3/APOE/HMGCR/CD36/PRKCD/ARFGEF1/TLR4/TNFRSF12A/HRAS/AGER/THBD/CRK/SERPING1/PDGFB/PLAUR/MYH9/WFDC1/MIR34A/HPSE/VKORC1/SERPINE1/CDKN1B/SRSF6/TEC/KANK1/SYTL4/PLEK/PDGFA/DMTN/F2R/NFE2L2/MYOZ1/MYLK/CLASP2/ANXA2P2/INSL3/RAB3A/REG3G/CAPN3/HRG/HBEGF/CD34/F3/ANXA2/MTOR/PRKCQ/ENPP4/TSPAN8/GJA1/PRKCA/SERPINF2/APCS/CD109	62
BP	GO:0031056	regulation of histone modification	60/7096	143/18670	0.1862	0.4043	0.3014	SPI1/PINK1/SKI/LMNA/BCL6/PHF19/CHTOP/UBE2N/ZNF304/PAF1/TGFB1/SIN3A/ZNF451/ARRB1/RUVBL2/NSD1/ZBTB7B/KAT7/VEGFA/SETD5/IL1B/UBR5/SIRT1/SETD7/PAXBP1/CDK9/LRRK2/PPARGC1A/FLCN/BCOR/ATM/MUC1/KMT2E/AKAP8/MAPK8/PRKD2/NOC2L/CTCF/ZMPSTE24/KDM4D/RNF20/CAMK2D/BRCA1/KAT2A/FMR1/EID1/OGT/JDP2/SET/KMT2B/SNCA/PAX7/PAX5/GCG/TADA3/PAXIP1/UBE2B/TET1/TAF7/ZNF335	60
BP	GO:0002021	response to dietary excess	13/7096	27/18670	0.1865	0.4043	0.3014	APPL2/SLC25A25/APOE/LEP/SCTR/ADRB1/OMA1/PPARGC1A/NMUR2/RMI1/ADRB2/UCP1/TRPV4	13
BP	GO:0006706	steroid catabolic process	13/7096	27/18670	0.1865	0.4043	0.3014	HSD17B14/CYP27A1/SRD5A1/SPP1/YWHAH/SCARB1/APOE/CYP1A2/STS/CYP27B1/CYP46A1/FGF23/SNX17	13
BP	GO:0006730	one-carbon metabolic process	13/7096	27/18670	0.1865	0.4043	0.3014	SFXN3/MTHFD2/AHCY/SHMT2/SFXN1/TYMS/AHCYL2/SHMT1/AHCYL1/DHFR/FPGS/ALDH1L1/MAT1A	13
BP	GO:0007176	regulation of epidermal growth factor-activated receptor activity	13/7096	27/18670	0.1865	0.4043	0.3014	FBXW7/CBLB/SOCS5/ZFYVE28/ZGPAT/NCF1/SHC1/SNX6/TSG101/VPS25/ADAM17/PSEN1/APP	13
BP	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	13/7096	27/18670	0.1865	0.4043	0.3014	RAB11A/CDK4/SIN3A/MTA3/DBF4B/RAD51B/CCND1/CDC25A/VPS4B/DTL/RCC2/APP/WNT10B	13
BP	GO:0032201	telomere maintenance via semi-conservative replication	13/7096	27/18670	0.1865	0.4043	0.3014	RPA1/PRIM2/POLD4/POLD2/RFC3/PCNA/RTEL1/POLD1/POLA1/POLA2/POLE4/FEN1/UPF1	13
BP	GO:0043032	positive regulation of macrophage activation	13/7096	27/18670	0.1865	0.4043	0.3014	TNIP2/WNT5A/CTSC/IL4R/MIR142/TLR4/CEBPA/TTBK1/LRRK2/TREM2/HAVCR2/LBP/TLR6	13
BP	GO:0045932	negative regulation of muscle contraction	13/7096	27/18670	0.1865	0.4043	0.3014	SOD1/PTGS2/RGS2/KCNE3/DOCK5/SRI/ADORA2B/ADRB2/PIK3CG/KCNMA1/ATP1A2/BIN1/TNNT1	13
BP	GO:0042773	ATP synthesis coupled electron transport	42/7096	98/18670	0.187	0.4053	0.3021	PINK1/UQCRC2/UQCR11/NDUFA8/NDUFC1/ISCU/NDUFB11/NDUFS3/NDUFA3/NDUFA11/UQCR10/COX7C/COX7A2L/NDUFA4/COX4I2/NDUFA1/COQ9/COA6/COX15/NDUFA10/NDUFB1/NDUFB5/UQCRQ/NDUFS1/NDUFB8/DNAJC15/NDUFB6/NDUFB3/SDHA/NDUFS7/NDUFV2/ND4/SDHD/TAZ/SNCA/UQCRB/NDUFB2/SDHAF2/COX6C/NDUFS2/NDUFA7/COX7B	42
BP	GO:0051928	positive regulation of calcium ion transport	52/7096	123/18670	0.1876	0.4055	0.3023	LILRA5/LILRA2/CXCL9/CXCL11/P2RX7/SLC9A1/CXCL10/PKD2/CXCL12/KCNE3/WFS1/P2RY6/ABL1/STIM2/GSTO1/CCL5/PLCG2/HOMER1/PDGFB/G6PD/SUMO1/SRI/BAX/ATP1B1/LPAR3/CAMK2A/F2R/MYLK/CEMIP/ORAI1/ANXA2P2/STAC2/CASQ1/CAPN3/BDKRB1/CD4/EHD3/LACRT/CACNB3/ANXA2/SNCA/CX3CL1/P2RX2/BAK1/GCG/CCL4/KCNE2/ADCYAP1R1/TRPV3/TRPV2/NTSR1/P2RX5	52
BP	GO:0010761	fibroblast migration	18/7096	39/18670	0.1876	0.4055	0.3023	SLC8A1/APPL2/TGFB1/PAK1/SGPL1/HYAL2/C5orf30/PML/TMEM201/WDPCP/RFFL/FER/DMTN/CORO1C/RCC2/ITGB1BP1/MTA2/APPL1	18
BP	GO:0032506	cytokinetic process	18/7096	39/18670	0.1876	0.4055	0.3023	KLHDC8B/NUP62/SPIRE1/CHMP4B/SNX18/ALKBH4/SNX33/MYH9/ARF1/CEP55/CHMP2A/KIF20B/CHMP1A/VPS4B/BIN3/RHOA/SNX9/CHMP1B	18
BP	GO:0032692	negative regulation of interleukin-1 production	18/7096	39/18670	0.1876	0.4055	0.3023	IGF1/CX3CR1/ACP5/IL1R2/NLRP3/TNFAIP3/NLRP12/GSTP1/SERPINB1/PML/MEFV/CPTP/APOA1/TREM2/CD33/CX3CL1/NR1H4/GHRL	18
BP	GO:0043001	Golgi to plasma membrane protein transport	18/7096	39/18670	0.1876	0.4055	0.3023	CSK/GGA2/VAMP5/SYS1/RAB31/GOPC/VAMP3/C16orf70/CNST/BBS2/PREPL/SPTBN1/GOLPH3L/KIF13A/ARFRP1/OPTN/RAB26/MACF1	18
BP	GO:0072595	maintenance of protein localization in organelle	18/7096	39/18670	0.1876	0.4055	0.3023	SUN2/PINK1/BARD1/SUPT7L/HSPA5/CDK5/SP100/PML/GPAA1/BBS4/KDELR3/KDELR2/INSIG1/TXN/TOPORS/RER1/ARL2BP/OS9	18
BP	GO:1904591	positive regulation of protein import	18/7096	39/18670	0.1876	0.4055	0.3023	PTGS2/FLNA/RAN/HCLS1/TGFB1/LEP/PRKCD/HYAL2/ZPR1/UBR5/MAVS/PDCD5/PSEN1/MAPK1/IFNG/CHP2/SMO/TARDBP	18
BP	GO:2000648	positive regulation of stem cell proliferation	18/7096	39/18670	0.1876	0.4055	0.3023	CX3CR1/KITLG/PTPRC/HIF1A/VEGFA/LTBP3/ASPM/N4BP2L2/DISC1/DCT/ATXN1L/TERT/NR2E1/CX3CL1/OTP/SMO/THPO/ZNF335	18
BP	GO:0070507	regulation of microtubule cytoskeleton organization	77/7096	186/18670	0.1887	0.4077	0.304	STMN1/MAP1S/NUP62/CIB1/ATF5/SENP6/GSK3B/KAT2B/CHMP4B/TRIM37/PSRC1/PAK1/CLIP1/CEP131/BICD2/STMN3/UBXN2B/PLK2/NPM1/ABL1/PAFAH1B1/CDK5RAP2/NSFL1C/ARHGEF2/CEP76/MAPRE1/SKA2/SPAG5/CDK2AP2/RAC1/MAPRE2/CDH5/CYLD/BICD1/DIXDC1/SPICE1/PARP3/CHMP2A/MARK2/CDKN1B/RANGRF/GEN1/CHMP1A/VPS4B/SLC39A12/CLASP2/BRCA1/GPSM2/CAV3/TUBB4A/CHORDC1/MAP1A/KAT2A/PRKAA1/SMC3/KATNB1/RNF4/SLAIN2/PKHD1/STAG1/TRAF3IP1/CEP120/NAV3/RHOA/TRPV4/AURKA/SNCA/CLIP3/TTBK2/MET/FGF13/CHMP1B/ROCK2/CEP85/ALMS1/CCNF/SKA3	77
BP	GO:0030220	platelet formation	10/7096	20/18670	0.1898	0.4088	0.3047	PTPN6/CIB1/SRF/ACTN1/NBEAL2/CASP3/VPS33A/TAL1/MYH9/MEF2C	10
BP	GO:0033630	positive regulation of cell adhesion mediated by integrin	10/7096	20/18670	0.1898	0.4088	0.3047	PTPN6/CIB1/CXCL13/CCL5/P2RY12/ADAM9/SKAP1/RET/IFT74/CD3E	10
BP	GO:0043931	ossification involved in bone maturation	10/7096	20/18670	0.1898	0.4088	0.3047	IGF1/DCHS1/THBS3/LEP/RYR1/BMP2/XYLT1/SEMA4D/RHOA/GREM1	10
BP	GO:0046514	ceramide catabolic process	10/7096	20/18670	0.1898	0.4088	0.3047	ASAH1/HEXB/GM2A/PSAP/GALC/PRKCD/GLA/NAGA/ACER3/NEU1	10
BP	GO:0046655	folic acid metabolic process	10/7096	20/18670	0.1898	0.4088	0.3047	MTHFD2/FOLR2/MTRR/SHMT2/SLC46A1/SHMT1/DHFR/FPGS/ALDH1L1/SLC25A32	10
BP	GO:0046931	pore complex assembly	10/7096	20/18670	0.1898	0.4088	0.3047	PLEKHA7/P2RX7/PDZD11/TSPAN33/NUP107/CCT8/NUP93/NUP205/BAD/RTN4	10
BP	GO:0071397	cellular response to cholesterol	10/7096	20/18670	0.1898	0.4088	0.3047	LRP8/AACS/HMGCS1/ABCA1/MLC1/INHBA/NFE2L1/DAG1/SMO/PTCH1	10
BP	GO:0097734	extracellular exosome biogenesis	10/7096	20/18670	0.1898	0.4088	0.3047	STAM/RAB11A/SDCBP/CHMP2A/TSG101/HGS/VPS4B/IFNG/CD34/RAB27A	10
BP	GO:2000774	positive regulation of cellular senescence	10/7096	20/18670	0.1898	0.4088	0.3047	ARG2/KRAS/EEF1E1/HMGA1/SIRT1/HLA-G/YPEL3/MIR34A/KIR2DL4/MIR146A	10
BP	GO:0006027	glycosaminoglycan catabolic process	27/7096	61/18670	0.1899	0.409	0.3049	FUCA1/HEXB/VCAN/NAGLU/CHP1/IDS/CD44/SLC9A1/HEXA/TGFB1/ARSB/SGSH/HYAL2/GNS/CSPG4/IDUA/GUSB/HPSE/HYAL3/PGLYRP4/BCAN/CEMIP/GPC2/STAB2/GPC4/LYVE1/SDC3	27
BP	GO:0097696	STAT cascade	69/7096	166/18670	0.1921	0.4137	0.3084	IGF1/CCR2/FYN/SOCS3/LYN/PPP2CA/PARP9/AKR1B1/STAT6/STAT3/PTPN2/MGAT5/ADIPOR1/CD40/STAT1/JAK2/PTPRC/IL15/IFNAR1/TNF/ERCC6/PKD2/DOT1L/IL7R/HCLS1/NMI/CYP1B1/SOCS5/LEP/FLT3/SOCS6/STAT5A/PTK6/CCL5/TNFRSF18/IL6ST/IL6/HDAC2/CLCF1/IFNK/OSM/HGS/DAB1/CD300A/INPP5F/FER/HES1/F2R/PWP1/CNTF/CNOT7/IL18/STAMBP/SOCS1/IL3/TSLP/IFNG/TNFSF18/RET/IFNAR2/IL12B/CSF1R/ARL2BP/GHR/IL26/SOCS2/IL23A/THPO/MIR146A	69
BP	GO:0034105	positive regulation of tissue remodeling	20/7096	44/18670	0.1932	0.4157	0.3099	VDR/ATP6AP1/SPP1/IL15/ADAM8/LTBP3/TNFRSF11A/PLEKHM1/MIR34A/TMEM64/BAX/EGFR/IL18/TFRC/DCSTAMP/HRG/IL12B/ROCK2/PRKCA/IL23A	20
BP	GO:0043647	inositol phosphate metabolic process	31/7096	71/18670	0.194	0.4173	0.3111	INPP1/PTAFR/IP6K1/PTK2B/SYNJ1/P2RY6/PLCG2/PPIP5K2/SYNJ2/OCRL/NUDT3/PLCL1/INPP5K/IMPA2/MTMR2/PLEK/PLCD1/PLCB1/PLD4/IPPK/PLCD4/MINPP1/PLCL2/SNCA/CD244/INPPL1/ADCYAP1R1/P2RY1/NTSR1/INPP5A/IMPA1	31
BP	GO:0055088	lipid homeostasis	63/7096	151/18670	0.1945	0.4182	0.3118	USF2/RBP1/FABP4/ABHD4/NPC2/FBXW7/SCARB1/SOAT1/CETP/APOE/PNPLA3/LRP5/LIMA1/NR1H2/CEBPA/AKR1C1/ABCA1/LAMTOR1/NR1D2/LDLR/ACOX1/EHD1/ACOX2/SIRT1/DGAT2/FABP3/TMEM97/IRS2/APOA5/MIR34A/MED13/ORMDL2/LCAT/ORMDL3/ABCG1/NR1H3/PNPLA5/ASGR2/RALY/ABCB4/SREBF2/NFE2L1/INSIG1/MALL/IL18/CAV3/NUS1/PRKAA1/COMMD9/APOA1/POLD1/ACOX3/RORA/ZBTB20/RTN4/ABCD1/SEC24A/NR1H4/SESN2/CD24/TM6SF2/C1QTNF3/G6PC	63
BP	GO:0051384	response to glucocorticoid	61/7096	146/18670	0.1951	0.4195	0.3128	FOS/DUSP1/ANXA1/CDKN1A/ZFP36/FOSB/SRD5A1/PTGS2/CREBRF/GSTP1/TNF/AKAP13/HNMT/IGFBP7/KRAS/AGL/ANXA3/TGFB1/ALAD/PTAFR/PCK2/TFAP4/FLT3/CASP3/AIF1/S100B/IGFBP2/IL1RN/KLF9/CCND1/IL6/PDCD7/SMYD3/SPARC/SCGB1A1/PAM/BCL2L11/PFKFB1/BCL2/PCNA/TYMS/CTSV/PDX1/DDIT4/NPAS4/EGFR/TPH2/SLIT2/MAOB/ADAM9/BAD/ZFP36L2/CPN1/CAD/FOSL1/EIF4E/RHOA/ALDH3A1/UCN3/FOXO3/SLIT3	61
BP	GO:0000380	alternative mRNA splicing, via spliceosome	33/7096	76/18670	0.1954	0.4198	0.313	CELF6/TRA2B/NSRP1/SRSF5/KHDRBS1/RNPS1/THRAP3/RBM7/ZBTB7A/SRSF10/MBNL1/RBM4/RBM4B/HNRNPA1/RBM8A/DHX9/SFSWAP/SRSF3/SFPQ/MBNL3/RSRC1/SRSF6/SREK1/SRSF7/HNRNPM/FMR1/CELF2/SRSF4/ZC3H10/RBM25/CELF3/SRRM4/SAP18	33
BP	GO:0046785	microtubule polymerization	33/7096	76/18670	0.1954	0.4198	0.313	STMN1/PSRC1/PAK1/CLIP1/RANBP9/CSNK1D/ABL1/CDK5RAP2/MAPRE1/TPPP3/RAC1/CDH5/ZNF207/MAP7D3/CDKN1B/TUBGCP3/CKAP5/NDEL1/RANGRF/SLC39A12/TUBG2/CLASP2/TUBGCP5/CAV3/TUBB4A/SLAIN2/NAV3/TRPV4/SNCA/CLIP3/MET/FGF13/TPPP	33
BP	GO:0048732	gland development	174/7096	434/18670	0.1959	0.4202	0.3133	CRIP1/VDR/USF2/ANXA1/ARF6/RBPJ/WNT5A/SOD1/SRSF5/SRD5A1/STAT6/THRA/HMGCL/SLC46A2/TNFAIP3/LSR/DBP/CEBPG/MAP2K1/WLS/FBXW7/SMAD2/CEBPB/JAK2/PSAP/HFE/TNF/EZH2/HMOX1/PKD2/KRAS/LRP5/PKM/RELA/CSNK2A2/UBE3A/TGFB1/AACS/HMGCS1/HGF/HIF1A/PCK2/FEM1B/SRF/INSR/LATS1/NRG1/ZBTB1/ZBTB7B/CEBPA/BMP2/VEGFA/ABL1/IGF2R/PAX8/STAT5A/CDKN1C/RAP1A/PML/OAS2/QDPR/CSNK2B/TNFRSF11A/CREB1/RAF1/ATP7B/BMP7/CCND1/ETV5/KALRN/IRS2/MESP1/GNPNAT1/CITED2/SULF2/MTX1/ETS1/PLAG1/ATM/EDA/PLXNA1/ALOX15B/PAM/BCL2L11/RXRA/BMPR1A/NRP1/ASH1L/PLXND1/EDAR/BCL2/PCNA/ZNF703/BMP4/TGM2/MPST/BAX/ID2/ASNS/CDKN1B/NME1/ITGA2/PPAT/TYMS/PDX1/RHBDD3/KDM5B/PDGFA/HNRNPD/PRMT5/GOT2/HES1/ZMPSTE24/ADA/HLX/MST1/EGFR/ORAI1/FADD/BCL11B/CAV3/KRT76/WNT1/PSEN1/HAMP/MAPK1/APOA1/NOTCH4/MSN/WDR77/TGFB3/FPGS/HNF1B/CAD/HNF1A/ATP7A/TFCP2L1/BTBD7/WDR35/MSX1/ELF5/POLB/GPX1/PITX1/CSF1R/HPN/AURKA/GHRH/FOXN1/RTN4/DAG1/MET/PNPT1/WNT10A/CCKBR/HOXA3/SMARCC1/GCM2/MGMT/FOXF1/ZDHHC21/OTP/SOCS2/GJA1/SMO/LBH/TWSG1/WT1/PTCH1/E2F8/APLN/CSN3/LAMA1/STRA6	174
BP	GO:0035510	DNA dealkylation	15/7096	32/18670	0.1961	0.4202	0.3133	ASCC3/ALKBH1/TET2/USP9X/APOBEC3G/TDG/APOBEC3C/OTUD4/APOBEC2/FTO/USP7/APOBEC3B/ALKBH2/MGMT/TET1	15
BP	GO:0039694	viral RNA genome replication	15/7096	32/18670	0.1961	0.4202	0.3133	PCBP1/MORC2/APOBEC3G/RAB29/APOBEC3C/INPP5K/RAB5A/TOP2B/SETDB1/PCBP2/FMR1/FBXL2/ATG16L2/ROCK2/TOP2A	15
BP	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	15/7096	32/18670	0.1961	0.4202	0.3133	FPR2/NOD2/LYN/FLT1/ATG14/TGFB1/PTK2B/FLT3/FGR/P2RY12/PDGFB/EPHA8/PTK2/CCL19/CCR7	15
BP	GO:0048841	regulation of axon extension involved in axon guidance	15/7096	32/18670	0.1961	0.4202	0.3133	WNT5A/SEMA4B/CXCL12/MEGF8/SEMA4A/VEGFA/SEMA4C/SEMA4D/SEMA6B/NRP1/SEMA3B/SEMA5A/SEMA5B/PLXNA3/BMPR2	15
BP	GO:0060325	face morphogenesis	15/7096	32/18670	0.1961	0.4202	0.3133	CSRNP1/SKI/PLEKHA1/RRAS/TGFB1/SGPL1/CRISPLD2/RAB3GAP1/TIPARP/ANKRD11/TGFB3/MSX1/MMP2/MYH3/STRA6	15
BP	GO:0061384	heart trabecula morphogenesis	15/7096	32/18670	0.1961	0.4202	0.3133	RBPJ/S1PR1/UBE4B/HEG1/SRF/NRG1/HEY1/BMP7/BMP5/BMPR1A/CAV3/HEY2/ENG/RBP4/FOXH1	15
BP	GO:0070570	regulation of neuron projection regeneration	15/7096	32/18670	0.1961	0.4202	0.3133	KLF4/RTN4R/GRN/LRIG2/SPP1/MAP2K1/CERS2/HGF/LRP1/NDEL1/INPP5F/RTN4RL1/CNTF/MAP4K4/KREMEN1	15
BP	GO:0006303	double-strand break repair via nonhomologous end joining	37/7096	86/18670	0.1973	0.4221	0.3147	USP51/MAD2L2/PARP9/BARD1/UBE2N/ERCC4/ZBTB7A/UIMC1/SETMAR/KDM2A/HERC2/XRCC5/SMCHD1/NUDT16L1/SUMO1/ATM/XRCC4/DTX3L/KAT5/MLH1/XRCC1/PARP3/ERCC1/LIG4/KDM4D/DCLRE1A/POLL/BRCA1/XRCC6/DCLRE1C/POLA1/PRPF19/LIG3/POLB/BRCC3/AUNIP/PAXIP1	37
BP	GO:0042058	regulation of epidermal growth factor receptor signaling pathway	37/7096	86/18670	0.1973	0.4221	0.3147	STAM/RHBDF2/PTPN2/ARAP1/NUP62/FBXW7/DUSP3/CBLB/SOCS5/ZFYVE28/ZGPAT/NCF1/PTK6/SHC1/SHKBP1/PDE6G/PLAUR/RNF115/DOK1/SNX6/MMP9/RNF126/TSG101/HGS/GRB2/FER/SPRY1/VPS25/EGFR/ADAM17/SPRY2/PSEN1/SNX5/HBEGF/APP/PTPRJ/RHBDF1	37
BP	GO:0060291	long-term synaptic potentiation	37/7096	86/18670	0.1973	0.4221	0.3147	NRGN/CX3CR1/LILRB2/LGMN/SQSTM1/EPHB2/APOE/GSK3B/TSHZ3/PTK2B/STAU1/PLK2/ABL1/S100B/AGER/CREB1/TYROBP/NPTN/ARC/CRTC1/ADCY1/RGS14/SHANK1/GRIN2C/SLC8A2/MAPK1/EIF2AK4/NR2E1/PRKCZ/RELN/APP/SNCA/SLC24A2/SLC8A3/CYP46A1/SHANK3/NTRK2	37
BP	GO:1903363	negative regulation of cellular protein catabolic process	37/7096	86/18670	0.1973	0.4221	0.3147	DDRGK1/ATRAID/LAMP3/HFE/FHIT/RYBP/CSNK2A2/ALAD/SGTA/OPHN1/FURIN/SDCBP/UBE2J1/PML/UCHL5/UBE2G2/MGAT3/KLHL40/DERL2/LAPTM4B/YOD1/USP7/ANXA2P2/MAP1A/WNT1/PSEN1/UBXN1/OGT/HSP90AB1/CLEC16A/ANXA2/BAG5/RGP1/USP19/SMARCC1/ERLEC1/OS9	37
BP	GO:0051205	protein insertion into membrane	22/7096	49/18670	0.1975	0.4224	0.3149	BMF/PMAIP1/YWHAH/SGTA/SFN/CASP8/BCL2L11/MAPK8/BCL2/BAX/GZMB/OXA1L/GET4/YWHAQ/RTP4/EGFR/YWHAE/BAD/PPP1R13B/MOAP1/YWHAG/UBL4A	22
BP	GO:0022037	metencephalon development	47/7096	111/18670	0.1983	0.4237	0.3159	DLL1/NAGLU/MAP2K1/LDB1/EZH2/PAK1/HSPA5/CDK5/ABL1/OPHN1/AIF1/ATRN/SEMA4C/CRK/PPARGC1A/CLP1/BCL2/ATIC/XRCC1/DAB1/HNRNPD/UQCRQ/LPAR1/CDK5R2/HOXB1/ARCN1/FZD4/WNT1/KAT2A/PSEN1/CBLN1/RORA/GNPAT/FAIM2/ATP7A/SPTBN2/KNDC1/ND4/TTBK2/LMX1A/TRNP1/WNT7A/CD3E/AGTPBP1/SMO/KIF14/CNTN1	47
BP	GO:0031623	receptor internalization	47/7096	111/18670	0.1983	0.4237	0.3159	HTR2B/EZR/SNX1/DNM3/FLOT1/ACKR3/RAB31/LILRB1/TBC1D5/ARRB1/CD36/LRPAP1/CD63/USP46/VEGFA/OPHN1/NUMB/PLCG2/SDCBP/SFRP4/LRP1/CXCR1/ATXN2/ARC/ARF1/DNM1/UBQLN2/DNM2/NEDD4/RAB5A/MTMR2/GRB2/CXCR2/CAV3/TFRC/FMR1/MKLN1/GRK4/AP2M1/ANKRD13D/PICK1/SNCA/GSG1L/PICALM/ATAD1/GREM1/APLN	47
BP	GO:0006479	protein methylation	74/7096	179/18670	0.1984	0.4237	0.3159	LMNA/PHF19/CHTOP/DPY30/FAM98B/SETDB2/ZNF304/EZH2/PAF1/WDR5B/VCPKMT/BTG2/DOT1L/SUV39H2/TET2/SETD4/PRMT9/NDUFAF7/NSD1/SETMAR/SETD5/TRMT112/FAM98A/PRDM4/SNRPB/SIRT1/METTL21A/SETD7/PAXBP1/SMYD3/METTL22/BCOR/LCMT1/FBL/KMT2E/NTMT1/BTG1/SUV39H1/ASH1L/SETD6/CTCF/BHMT/SETDB1/ETF1/PRMT5/COPRS/KDM4D/RNF20/PWP1/BRCA1/PCMTD2/ICMT/PRDM2/PRDM6/OGT/RAB3B/RLF/FBLL1/MEN1/PCMTD1/CARM1/KMT2B/RAB3D/PAX7/PAX5/GCG/EZH1/PAXIP1/PRMT1/WDR82/NR1H4/WDR5/TET1/ZNF335	74
BP	GO:0008213	protein alkylation	74/7096	179/18670	0.1984	0.4237	0.3159	LMNA/PHF19/CHTOP/DPY30/FAM98B/SETDB2/ZNF304/EZH2/PAF1/WDR5B/VCPKMT/BTG2/DOT1L/SUV39H2/TET2/SETD4/PRMT9/NDUFAF7/NSD1/SETMAR/SETD5/TRMT112/FAM98A/PRDM4/SNRPB/SIRT1/METTL21A/SETD7/PAXBP1/SMYD3/METTL22/BCOR/LCMT1/FBL/KMT2E/NTMT1/BTG1/SUV39H1/ASH1L/SETD6/CTCF/BHMT/SETDB1/ETF1/PRMT5/COPRS/KDM4D/RNF20/PWP1/BRCA1/PCMTD2/ICMT/PRDM2/PRDM6/OGT/RAB3B/RLF/FBLL1/MEN1/PCMTD1/CARM1/KMT2B/RAB3D/PAX7/PAX5/GCG/EZH1/PAXIP1/PRMT1/WDR82/NR1H4/WDR5/TET1/ZNF335	74
BP	GO:1901606	alpha-amino acid catabolic process	45/7096	106/18670	0.1984	0.4237	0.3159	ASRGL1/ATP2B4/HIBADH/ARG2/IL4I1/HMGCL/AHCY/ALDH7A1/PHYKPL/ALDH6A1/PCBD1/HAL/DDAH2/HNMT/FAH/AUH/MTRR/IDO1/GSTZ1/QDPR/OGDH/ALDH4A1/GLUD1/DAO/ADHFE1/MCCC1/KYNU/HAAO/SHMT2/GLUD2/ALDH8A1/PPAT/GLS/GOT2/AGXT2/SHMT1/IDO2/AMT/AMDHD1/BCAT2/HYKK/HMGCLL1/TDO2/MAT1A/PIPOX	45
BP	GO:1904062	regulation of cation transmembrane transport	138/7096	342/18670	0.1988	0.4243	0.3164	CRHBP/SLC8A1/CCR2/FYN/KCNMB1/PTPN6/ATP2B4/LYN/PINK1/OXSR1/KCNAB2/DIAPH1/KLHL24/CHP1/FLNA/CTSS/NETO2/ACTN4/RGS2/YWHAH/CXCL9/CXCL11/EPHB2/SLC31A2/SLC9A1/CXCL10/FXYD5/TESC/PKD2/FXYD6/ANXA3/TGFB1/KCNE3/KCNIP2/ISCU/PTK2B/MYO5A/CD63/CORO1A/P2RY6/SCN1B/CNIH3/TCIRG1/AHNAK/PDE4B/ABL1/STIM2/DNAJC30/GSTO1/PLCG2/DAPK1/DMD/CHCHD10/HOMER1/ATP1B2/TMC2/G6PD/PPARGC1A/ARC/SUMO1/PSEN2/SRI/ATP1B3/ARF1/LRRC52/MMP9/FXYD1/DNM2/NEDD4/BAX/SHISA9/ATP1B1/PRKACA/KCNAB1/ADRB2/FHL1/RANGRF/KCNQ1/CYBA/SHANK1/F2R/SCN2B/RASGRF1/COMMD1/CAMK2D/DPP6/CEMIP/WWP2/AMIGO1/CAV3/LRRC7/STAC2/FMR1/HAMP/FXYD7/GPR35/YWHAE/CASQ1/TREM2/PLA2G6/CAPN3/CASQ2/HRC/IFNG/KCNIP1/ATP7A/FXYD2/KCNS2/KIF5B/BDKRB1/EHD3/TMEM38B/LACRT/PIK3CG/CACNB3/REM2/SNTA1/OPRL1/RELN/LIME1/APP/SNCA/CX3CL1/GSG1L/SLN/FXYD3/TMC1/KCNE2/ATP1A2/SHISA8/NLGN2/SHANK3/GRIA2/KEL/BIN1/NTSR1/WNK2/MEF2C	138
BP	GO:0010524	positive regulation of calcium ion transport into cytosol	24/7096	54/18670	0.2008	0.4244	0.3164	CXCL9/CXCL11/P2RX7/CXCL10/PKD2/P2RY6/ABL1/GSTO1/SRI/BAX/F2R/CEMIP/CASQ1/CAPN3/BDKRB1/CD4/LACRT/SNCA/CX3CL1/P2RX2/BAK1/ADCYAP1R1/NTSR1/P2RX5	24
BP	GO:0030042	actin filament depolymerization	24/7096	54/18670	0.2008	0.4244	0.3164	MICAL1/TMOD3/LIMA1/TWF2/RDX/CFL2/CAPZA2/SWAP70/CAPG/MICAL2/CAPZA1/SH3BP1/SPTBN1/AVIL/CFL1/TRIOBP/ADD3/PLEK/SEMA5A/DMTN/LMOD3/SCIN/SPTA1/SPTBN2	24
BP	GO:0070206	protein trimerization	24/7096	54/18670	0.2008	0.4244	0.3164	ALOX5AP/SKI/DISP1/NUP62/STEAP4/GNB1/MIF/CD74/TRIM22/HTRA2/HSF4/HLA-G/ITLN1/MGST1/TRIM21/CD247/MLKL/TRAF2/CLYBL/ATXN10/TRIM6/SIGMAR1/PNPT1/C1QTNF3	24
BP	GO:0017156	calcium ion regulated exocytosis	64/7096	154/18670	0.2032	0.4244	0.3164	APBA1/STX11/RAP1B/SYT11/CHP1/P2RX7/CTBP2/GSK3B/PPP3CB/STXBP1/UNC13B/SYNJ1/FBXL20/CDK5/VAMP3/RAB3GAP1/DTNBP1/RAP1A/BLOC1S6/DOC2B/PREPL/LRRK2/SYT6/ADCY1/ARF1/P2RX1/ADORA2B/RPH3AL/VPS18/NAPA/GNAI2/RAB5A/HYAL3/CAMK2A/CHRM2/DNM1L/CHRNA4/CDK5R2/SYT13/ATP2A2/SCIN/DVL1/PSEN1/FMR1/RAB3A/CHRNB2/P2RY4/PPFIA3/SYT9/SYT1/SYT2/VAMP1/STXBP3/DOC2A/SNAP29/SYT4/CADPS2/SYT5/SCAMP5/SNCA/RIMS2/WNT7A/CACNA1H/P2RY1	64
BP	GO:0042307	positive regulation of protein import into nucleus	17/7096	37/18670	0.2032	0.4244	0.3164	PTGS2/FLNA/RAN/HCLS1/TGFB1/LEP/PRKCD/HYAL2/ZPR1/UBR5/MAVS/PSEN1/MAPK1/IFNG/CHP2/SMO/TARDBP	17
BP	GO:0043029	T cell homeostasis	17/7096	37/18670	0.2032	0.4244	0.3164	TSC22D3/PMAIP1/SLC46A2/P2RX7/TGFB1/PPP3CB/CORO1A/TCIRG1/CASP3/BCL2L11/BCL2/BAX/PPP2R3C/LGALS9/FADD/FOXN1/CACNA1F	17
BP	GO:0045923	positive regulation of fatty acid metabolic process	17/7096	37/18670	0.2032	0.4244	0.3164	ANXA1/PTGS2/SLC45A3/CD74/ELOVL5/LPGAT1/NR1H2/IL1B/IRS2/PPARGC1A/MLYCD/APOA5/NR1H3/CPT1A/PPARA/NR4A3/ABCD1	17
BP	GO:0046006	regulation of activated T cell proliferation	17/7096	37/18670	0.2032	0.4244	0.3164	IGF1/CLC/CASP3/AGER/ICOSLG/HMGB1/IGFBP2/PDCD1LG2/IL12RB1/CD274/LGALS9/BTN2A2/IL18/FADD/IL12B/CD24/IL23A	17
BP	GO:1902100	negative regulation of metaphase/anaphase transition of cell cycle	17/7096	37/18670	0.2032	0.4244	0.3164	DUSP1/MAD2L2/DYNC1LI1/SPDL1/KLHL22/CDK5RAP2/ZNF207/LCMT1/ATM/BUB3/NDC80/GEN1/ZW10/MOS/CDC20/PCID2/IK	17
BP	GO:0001885	endothelial cell development	26/7096	59/18670	0.2035	0.4244	0.3164	MYADM/EZR/COL23A1/S1PR3/RAP1B/F11R/TNF/RDX/RAPGEF2/HEG1/RAP2C/VEGFA/IL1B/RAP1A/PPP1R16B/CDH5/GSTM3/VEZF1/NOTCH4/MSN/COL18A1/GPX1/ENG/MET/WNT7A/ROCK2	26
BP	GO:0008333	endosome to lysosome transport	26/7096	59/18670	0.2035	0.4244	0.3164	FAM160A2/ATG14/M6PR/VPS41/DENND3/TRAK2/VPS33A/HOOK2/SNX27/DTX3L/HOOK3/VPS18/TSG101/ADRB2/VIPAS39/KIF13A/VPS4B/RAB7B/GPRASP1/STX8/TRAK1/CLEC16A/VPS16/VCP/SNX16/BIN1	26
BP	GO:0010518	positive regulation of phospholipase activity	26/7096	59/18670	0.2035	0.4244	0.3164	HTR2B/S1PR4/FLT1/GNA15/PLAA/PTAFR/GNAQ/LPAR2/ARF4/P2RY6/HRAS/CCL5/P2RY12/ITK/ARHGAP6/NMUR2/ARL1/LPAR1/EGFR/ABL2/GNA13/TXK/PRKCZ/ADCYAP1R1/RASGRP4/NTRK2	26
BP	GO:0042130	negative regulation of T cell proliferation	26/7096	59/18670	0.2035	0.4244	0.3164	PTPN6/LILRB2/ARG2/GPNMB/TNFRSF14/CEBPB/TNFRSF21/LILRB1/TGFB1/IL20RB/ZBTB7B/CASP3/IDO1/HLA-G/CTLA4/GLMN/VSIG4/SCGB1A1/PDCD1LG2/BMP4/CD274/LGALS9/BTN2A2/HAVCR2/CD80/TWSG1	26
BP	GO:0061077	chaperone-mediated protein folding	26/7096	59/18670	0.2035	0.4244	0.3164	HSPA6/CD74/DNAJB1/SGTA/CRTAP/HSPB1/HSPA5/FKBP5/DFFA/DNAJB5/CLU/TOR1B/PDCD5/PTGES3/DNAJC7/DNAJB4/TOR1A/PEX19/HSPA1L/CHORDC1/HSPB6/ST13/UNC45B/PPIB/DNAJC24/DNAJC18	26
BP	GO:0006851	mitochondrial calcium ion transmembrane transport	12/7096	25/18670	0.2037	0.4244	0.3164	YME1L1/MCU/AFG3L2/PSEN2/MICU1/VDAC1/LETM1/PARL/MICU3/PMPCB/SLC8A3/MICU2	12
BP	GO:0009299	mRNA transcription	12/7096	25/18670	0.2037	0.4244	0.3164	STAT3/PPARD/FLNA/ATF4/LMO2/HIF1A/SRF/ZBTB1/MYOG/ARNT/HIPK3/TFCP2	12
BP	GO:0021680	cerebellar Purkinje cell layer development	12/7096	25/18670	0.2037	0.4244	0.3164	DLL1/NAGLU/LDB1/HSPA5/UQCRQ/ARCN1/RORA/FAIM2/ATP7A/SPTBN2/AGTPBP1/KIF14	12
BP	GO:0032104	regulation of response to extracellular stimulus	12/7096	25/18670	0.2037	0.4244	0.3164	NUCB2/LEP/BBS2/MKKS/BBS4/TRIM24/PPARA/CYP27B1/MTOR/SPX/NENF/GHRL	12
BP	GO:0032107	regulation of response to nutrient levels	12/7096	25/18670	0.2037	0.4244	0.3164	NUCB2/LEP/BBS2/MKKS/BBS4/TRIM24/PPARA/CYP27B1/MTOR/SPX/NENF/GHRL	12
BP	GO:0035336	long-chain fatty-acyl-CoA metabolic process	12/7096	25/18670	0.2037	0.4244	0.3164	FAR2/ACOT7/ACSL5/ELOVL5/ACSL4/TECR/ELOVL7/DGAT2/ACSL6/FAR1/ELOVL6/HSD17B12	12
BP	GO:0048103	somatic stem cell division	12/7096	25/18670	0.2037	0.4244	0.3164	NUMB/ARHGEF2/ASPM/AKNA/DCT/ZFP36L2/NUMBL/FZD7/SOX5/FGF13/WNT7A/LBH	12
BP	GO:0050901	leukocyte tethering or rolling	12/7096	25/18670	0.2037	0.4244	0.3164	CCR2/CX3CR1/SELL/ITGB7/TNF/CXCL12/PTAFR/LEP/ITGA4/GCNT1/SELPLG/MADCAM1	12
BP	GO:0051560	mitochondrial calcium ion homeostasis	12/7096	25/18670	0.2037	0.4244	0.3164	BCAP31/FIS1/MCU/AFG3L2/PDZD8/DISC1/ANXA6/TGM2/MICU1/LETM1/SLC8A3/MICU2	12
BP	GO:0061050	regulation of cell growth involved in cardiac muscle cell development	12/7096	25/18670	0.2037	0.4244	0.3164	IGF1/RGS2/PAK1/PARP2/CTDP1/G6PD/YY1/PPARA/CAV3/HAMP/PIN1/MTOR	12
BP	GO:0061217	regulation of mesonephros development	12/7096	25/18670	0.2037	0.4244	0.3164	LGR4/MAGED1/TGFB1/VEGFA/PAX8/BASP1/BMP4/HNF1B/TACSTD2/WNT2B/SMO/WT1	12
BP	GO:0072677	eosinophil migration	12/7096	25/18670	0.2037	0.4244	0.3164	PTGER4/ADAM8/CCL5/CCL7/CCL13/CCL8/CD300A/CCL26/DAPK2/CX3CL1/CCL4/CCL24	12
BP	GO:2000104	negative regulation of DNA-dependent DNA replication	12/7096	25/18670	0.2037	0.4244	0.3164	ATG7/BCL6/FBXW7/SLFN11/GMNN/ZNF830/DONSON/TIPIN/TIMELESS/SMC3/LIG3/ZRANB3	12
BP	GO:0007565	female pregnancy	79/7096	192/18670	0.204	0.4244	0.3164	CRHBP/JUNB/FOS/VDR/NAMPT/FOSB/SOD1/ITGA5/AKR1B1/CAPN2/PTGS2/SPP1/PPARD/RGS2/PZP/AGO2/HFE/IGFBP7/KRAS/DAZAP1/TGFB1/MAGED2/HPGD/LEP/EPOR/ACSL4/ARHGDIB/IDO1/IL1B/STOX2/CTSB/UBE2A/THBD/IGFBP2/ADCY7/ACVR1B/ETS1/SCGB1A1/PAM/EMP2/RXRA/ASH1L/MMP9/BCL2/TIMP1/APOL2/TLE6/ITGA2/PPAT/PCSK5/CTSV/LGALS9/AMBP/ITGA3/GOT2/CALR/STS/C1QBP/ADIPOR2/MAPK1/PSG7/CYP27B1/PLA2G6/TGFB3/HAVCR2/CAD/FOSL1/PTHLH/TFCP2L1/MEN1/MMP2/MTOR/GJA1/SYDE1/PSG5/GHRL/PSG4/BMPR2/PSG11	79
BP	GO:0002182	cytoplasmic translational elongation	6/7096	11/18670	0.2044	0.4244	0.3164	DPH3/DPH5/DPH2/CPEB3/DNAJC24/CPEB2	6
BP	GO:0002328	pro-B cell differentiation	6/7096	11/18670	0.2044	0.4244	0.3164	FLT3/FLCN/FNIP1/LIG4/HES1/SOX4	6
BP	GO:0002517	T cell tolerance induction	6/7096	11/18670	0.2044	0.4244	0.3164	LILRB2/CLC/IDO1/HLA-G/ICOS/CD3E	6
BP	GO:0002604	regulation of dendritic cell antigen processing and presentation	6/7096	11/18670	0.2044	0.4244	0.3164	NOD2/SLC11A1/FGL2/CD74/CCL19/CCR7	6
BP	GO:0003093	regulation of glomerular filtration	6/7096	11/18670	0.2044	0.4244	0.3164	PTPRO/PDGFB/EMP2/CYBA/F2R/GJA1	6
BP	GO:0005984	disaccharide metabolic process	6/7096	11/18670	0.2044	0.4244	0.3164	FBP1/MGAM/IDUA/GAA/B4GALT1/TREH	6
BP	GO:0006558	L-phenylalanine metabolic process	6/7096	11/18670	0.2044	0.4244	0.3164	ASRGL1/IL4I1/PCBD1/FAH/GSTZ1/QDPR	6
BP	GO:0006559	L-phenylalanine catabolic process	6/7096	11/18670	0.2044	0.4244	0.3164	ASRGL1/IL4I1/PCBD1/FAH/GSTZ1/QDPR	6
BP	GO:0006620	posttranslational protein targeting to endoplasmic reticulum membrane	6/7096	11/18670	0.2044	0.4244	0.3164	CHMP4B/SEC62/SGTA/SEC61B/HSPA5/SEC61A2	6
BP	GO:0006853	carnitine shuttle	6/7096	11/18670	0.2044	0.4244	0.3164	SLC25A20/CPT2/ACACB/PRKAG2/CPT1A/THRSP	6
BP	GO:0009113	purine nucleobase biosynthetic process	6/7096	11/18670	0.2044	0.4244	0.3164	GMPS/PAICS/PRPS1/PPAT/ADA/SHMT1	6
BP	GO:0009629	response to gravity	6/7096	11/18670	0.2044	0.4244	0.3164	FOS/PKM/PTAFR/SPARC/MYOG/FOSL1	6
BP	GO:0014870	response to muscle inactivity	6/7096	11/18670	0.2044	0.4244	0.3164	PKM/MYOG/MTMR4/HDAC4/CASQ1/DAG1	6
BP	GO:0021561	facial nerve development	6/7096	11/18670	0.2044	0.4244	0.3164	ADARB1/EGR2/NRP1/NRP2/HOXB1/PLXNA3	6
BP	GO:0021604	cranial nerve structural organization	6/7096	11/18670	0.2044	0.4244	0.3164	EGR2/NRP1/NRP2/KCNA2/HOXB1/PLXNA3	6
BP	GO:0021610	facial nerve morphogenesis	6/7096	11/18670	0.2044	0.4244	0.3164	ADARB1/EGR2/NRP1/NRP2/HOXB1/PLXNA3	6
BP	GO:0021670	lateral ventricle development	6/7096	11/18670	0.2044	0.4244	0.3164	DPCD/NUMB/TSKU/KDM2B/NUMBL/PAX5	6
BP	GO:0031652	positive regulation of heat generation	6/7096	11/18670	0.2044	0.4244	0.3164	SLC27A1/PTGS2/TNF/IL1B/TNFRSF11A/APLN	6
BP	GO:0032276	regulation of gonadotropin secretion	6/7096	11/18670	0.2044	0.4244	0.3164	LEP/INHBA/NPVF/INHA/TACR2/KISS1	6
BP	GO:0032351	negative regulation of hormone metabolic process	6/7096	11/18670	0.2044	0.4244	0.3164	ATP1A1/AKR1C3/NFKB1/BMP2/BMP5/CYP27B1	6
BP	GO:0032494	response to peptidoglycan	6/7096	11/18670	0.2044	0.4244	0.3164	NOD2/NLRP3/IRAK3/RELA/IL6/TREM2	6
BP	GO:0032908	regulation of transforming growth factor beta1 production	6/7096	11/18670	0.2044	0.4244	0.3164	FURIN/ATP6AP2/TYROBP/CD2AP/LAPTM4B/CX3CL1	6
BP	GO:0033234	negative regulation of protein sumoylation	6/7096	11/18670	0.2044	0.4244	0.3164	HMG20A/RELA/PIAS3/CAPN3/GNL3L/HMG20B	6
BP	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase	6/7096	11/18670	0.2044	0.4244	0.3164	ETFA/ACADM/ACADS/ETFDH/ETFB/ACADVL	6
BP	GO:0045217	cell-cell junction maintenance	6/7096	11/18670	0.2044	0.4244	0.3164	PLEKHA7/KIFC3/F2R/CSF1R/PRTN3/NLGN2	6
BP	GO:0045351	type I interferon biosynthetic process	6/7096	11/18670	0.2044	0.4244	0.3164	IRF7/TICAM1/NMI/TLR4/TLR8/TLR3	6
BP	GO:0045793	positive regulation of cell size	6/7096	11/18670	0.2044	0.4244	0.3164	TMEM123/CDK4/PRR16/ATP7A/RET/HSP90AB1	6
BP	GO:0045919	positive regulation of cytolysis	6/7096	11/18670	0.2044	0.4244	0.3164	P2RX7/LILRB1/PGLYRP4/RRAGA/LBP/CFHR5	6
BP	GO:0046185	aldehyde catabolic process	6/7096	11/18670	0.2044	0.4244	0.3164	ADH5/ESD/PNKD/AKR1A1/HAGH/AGXT2	6
BP	GO:0046439	L-cysteine metabolic process	6/7096	11/18670	0.2044	0.4244	0.3164	AHCY/APIP/MTRR/ENOPH1/AHCYL2/AHCYL1	6
BP	GO:0046607	positive regulation of centrosome cycle	6/7096	11/18670	0.2044	0.4244	0.3164	NUP62/UBXN2B/NSFL1C/VPS4B/CEP120/ROCK2	6
BP	GO:0046950	cellular ketone body metabolic process	6/7096	11/18670	0.2044	0.4244	0.3164	HMGCL/AACS/BDH1/BDH2/OXCT1/HMGCLL1	6
BP	GO:0048548	regulation of pinocytosis	6/7096	11/18670	0.2044	0.4244	0.3164	APPL2/ACTN4/AXL/NR1H2/NR1H3/APPL1	6
BP	GO:0048742	regulation of skeletal muscle fiber development	6/7096	11/18670	0.2044	0.4244	0.3164	MYOG/BCL2/HDAC4/LMOD3/SHOX2/MYF6	6
BP	GO:0051013	microtubule severing	6/7096	11/18670	0.2044	0.4244	0.3164	KATNA1/TTLL11/KATNAL1/KATNB1/TTLL6/FIGNL1	6
BP	GO:0051024	positive regulation of immunoglobulin secretion	6/7096	11/18670	0.2044	0.4244	0.3164	HLA-E/GPI/IL6/TNFSF4/TNFRSF4/RBP4	6
BP	GO:0051561	positive regulation of mitochondrial calcium ion concentration	6/7096	11/18670	0.2044	0.4244	0.3164	BCAP31/FIS1/MCU/TGM2/MICU1/MICU2	6
BP	GO:0060837	blood vessel endothelial cell differentiation	6/7096	11/18670	0.2044	0.4244	0.3164	DLL1/RBPJ/HEY1/MIR34A/NRP1/HEY2	6
BP	GO:0070189	kynurenine metabolic process	6/7096	11/18670	0.2044	0.4244	0.3164	IDO1/KYNU/ALDH8A1/GOT2/IDO2/TDO2	6
BP	GO:0070213	protein auto-ADP-ribosylation	6/7096	11/18670	0.2044	0.4244	0.3164	PARP16/PARP12/PARP3/TIPARP/PARP11/PARP6	6
BP	GO:0070673	response to interleukin-18	6/7096	11/18670	0.2044	0.4244	0.3164	ALOX5/IL18R1/IL18BP/PDGFB/IL18/IL18RAP	6
BP	GO:0072110	glomerular mesangial cell proliferation	6/7096	11/18670	0.2044	0.4244	0.3164	EGR1/BMP7/PDGFB/BMP4/WT1/PDGFD	6
BP	GO:0072321	chaperone-mediated protein transport	6/7096	11/18670	0.2044	0.4244	0.3164	TIMM8B/CLU/TOR1A/PEX19/CLIP3/TIMM9	6
BP	GO:0072683	T cell extravasation	6/7096	11/18670	0.2044	0.4244	0.3164	CCR2/IL27RA/CD99/CRK/CD99L2/FADD	6
BP	GO:0098814	spontaneous synaptic transmission	6/7096	11/18670	0.2044	0.4244	0.3164	AGER/DOC2B/SYT1/DOC2A/APP/RIMS2	6
BP	GO:0098883	synapse pruning	6/7096	11/18670	0.2044	0.4244	0.3164	ITGAM/CX3CR1/CDK5/TREM2/C1QC/CX3CL1	6
BP	GO:0098887	neurotransmitter receptor transport, endosome to postsynaptic membrane	6/7096	11/18670	0.2044	0.4244	0.3164	RAB11A/GRIPAP1/GRIP1/RAB8A/GRASP/LRRC7	6
BP	GO:0099639	neurotransmitter receptor transport, endosome to plasma membrane	6/7096	11/18670	0.2044	0.4244	0.3164	RAB11A/GRIPAP1/GRIP1/RAB8A/GRASP/LRRC7	6
BP	GO:1900247	regulation of cytoplasmic translational elongation	6/7096	11/18670	0.2044	0.4244	0.3164	DPH3/DPH5/DPH2/CPEB3/DNAJC24/CPEB2	6
BP	GO:1901077	regulation of relaxation of muscle	6/7096	11/18670	0.2044	0.4244	0.3164	PDE4B/TIFAB/SRI/CAMK2D/HRC/SLN	6
BP	GO:1901569	fatty acid derivative catabolic process	6/7096	11/18670	0.2044	0.4244	0.3164	ACOT7/BDH1/OXCT1/CYP4F3/ABCD1/ABHD16A	6
BP	GO:1901678	iron coordination entity transport	6/7096	11/18670	0.2044	0.4244	0.3164	SLC48A1/FLVCR2/ABCB6/SLC46A1/HRG/ABCB7	6
BP	GO:1902221	erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process	6/7096	11/18670	0.2044	0.4244	0.3164	ASRGL1/IL4I1/PCBD1/FAH/GSTZ1/QDPR	6
BP	GO:1902222	erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process	6/7096	11/18670	0.2044	0.4244	0.3164	ASRGL1/IL4I1/PCBD1/FAH/GSTZ1/QDPR	6
BP	GO:1904468	negative regulation of tumor necrosis factor secretion	6/7096	11/18670	0.2044	0.4244	0.3164	IL27RA/ARG2/SYT11/CX3CL1/NR1H4/GHRL	6
BP	GO:2000392	regulation of lamellipodium morphogenesis	6/7096	11/18670	0.2044	0.4244	0.3164	ENPP2/CD44/ARPIN/CORO1B/KANK1/CORO1C	6
BP	GO:2000767	positive regulation of cytoplasmic translation	6/7096	11/18670	0.2044	0.4244	0.3164	METTL3/CNBP/NCK1/DHX9/YBX3/MTOR	6
BP	GO:0045670	regulation of osteoclast differentiation	28/7096	64/18670	0.2055	0.4263	0.3178	FOS/SIGLEC15/NOTCH2/ATP6AP1/KLF10/LILRB3/FBXW7/CEBPB/TNF/LILRB1/LILRB4/TRAF6/TLR4/MITF/CREB1/TYROBP/TFE3/TMEM64/PIAS3/LRRC17/TREM2/IFNG/CLDN18/TLR3/IL12B/MTOR/SLC9B2/IL23A	28
BP	GO:0048247	lymphocyte chemotaxis	28/7096	64/18670	0.2055	0.4263	0.3178	CCR2/OXSR1/WNT5A/CXCL11/ADAM8/CXCL10/PTK2B/CXCL13/CCL5/CCL7/CKLF/SLC12A2/CCL13/TMEM102/CCL8/PIK3CD/CH25H/ADAM17/CCL20/CCL26/C10orf99/PIK3CG/GPR183/CX3CL1/CXCR3/CCL19/CCL4/CCL24	28
BP	GO:1900449	regulation of glutamate receptor signaling pathway	28/7096	64/18670	0.2055	0.4263	0.3178	CRHBP/CCR2/FYN/PINK1/KLHL24/NETO2/EPHB2/ANXA3/PTK2B/CNIH3/DAPK1/PPARGC1A/ARC/SHISA9/ADRB2/SHANK1/RASGRF1/LRRC7/IFNG/RELN/APP/CX3CL1/GSG1L/SHISA8/NLGN2/SHANK3/GRIA2/MEF2C	28
BP	GO:0006720	isoprenoid metabolic process	58/7096	139/18670	0.2058	0.4268	0.3182	ALDH3A2/RBP1/SRD5A1/AKR1B1/NPC2/PPARD/ALDH1A1/RDH10/ADH5/PHYH/RETSAT/AKR1C3/APOE/HMGCR/DHRS3/DHRS9/LRP8/HMGCS1/CYP1B1/RDH16/NAPEPLD/HTRA2/AKR1C1/CYP2S1/PDSS1/PLB1/FDPS/LRP1/DGAT2/DPM1/RDH12/IDI1/CYP2D6/CYP1A2/CYP26B1/ALDH8A1/RDH5/SCPEP1/AKR1B10/ADH1B/EGFR/NUS1/DHDDS/SRD5A3/GPC2/APOA1/BCO2/CYP26A1/GPC4/SDC3/CRABP2/RLBP1/ADH7/CYP2C8/RBP4/DPAGT1/PNPLA4/STRA6	58
BP	GO:0006338	chromatin remodeling	75/7096	182/18670	0.2063	0.4277	0.3189	BAZ1A/DR1/CHRAC1/MYC/CHD1/KAT2B/SUV39H2/ACTB/ANP32E/BPTF/ZBTB7A/SYCP3/CENPW/MORC2/PAK1/RUVBL2/ZBTB1/RUVBL1/MBD3/RBBP7/NPM1/SATB2/HMGA1/CENPT/RBBP4/CENPN/HMGB1/SMCHD1/SMARCAD1/ARID1B/SMARCA1/INO80C/CENPC/KDM4B/ACTR5/HDAC2/PTMA/HNRNPC/CBX3/HMGB2/HDAC4/NUDT5/SUPT4H1/RSF1/PBRM1/KDM5B/CENPK/KDM6B/KDM4D/TAF6L/VPS72/KAT2A/BRDT/SCMH1/BAZ2B/SMARCC2/CENPA/KDM5C/NASP/RB1/SMARCA5/KMT2B/HDAC5/CENPL/PAX7/TOP1/CENPI/SMARCC1/EZH1/MTA2/ACTL6A/MIS18BP1/DAXX/HMGB4/KDM4A	75
BP	GO:2000243	positive regulation of reproductive process	30/7096	69/18670	0.207	0.4291	0.3199	WNT5A/RETN/CIB1/LFNG/AGO2/PTAFR/INSR/PLB1/ACVR1B/CITED2/CCDC87/HDAC2/HDAC4/FAM170B/CDC25A/INHBA/HYAL3/PLCB1/C1QBP/VIP/LHFPL2/MSX1/ANKRD31/AURKA/UBE2B/SYDE1/CACNA1H/WT1/P2RY1/POMZP3	30
BP	GO:0007368	determination of left/right symmetry	50/7096	119/18670	0.2085	0.43	0.3205	DLL1/ACVR2B/WNT5A/DISP1/BBS5/AP1B1/SMAD2/LRRC6/SETDB2/IFT172/PKD2/IFT57/MIB1/KIF3B/HIF1A/MEGF8/ARL13B/SRF/DPCD/MICAL2/PSKH1/RFX3/MKKS/MESP1/IFT52/CITED2/BBS4/DNAI2/DYNC2LI1/BBS7/PCSK5/MKS1/CCDC151/C9orf116/CFC1/PCSK6/PSEN1/DNAI1/ENG/IFT74/FOXF1/NEK8/CER1/GJA1/SMO/DAAM2/C2CD3/GAS8/MEF2C/FOXH1	50
BP	GO:0016079	synaptic vesicle exocytosis	50/7096	119/18670	0.2085	0.43	0.3205	APBA1/STX11/RAP1B/SYT11/P2RX7/CTBP2/GSK3B/STXBP1/UNC13B/SYNJ1/FBXL20/CDK5/RAB3GAP1/DTNBP1/RAP1A/BLOC1S6/DOC2B/PREPL/LRRK2/ADCY1/P2RX1/ADORA2B/VPS18/NAPA/RAB5A/CAMK2A/CHRM2/DNM1L/CHRNA4/ATP2A2/DVL1/PSEN1/FMR1/RAB3A/CHRNB2/P2RY4/PPFIA3/SYT9/SYT1/SYT2/VAMP1/DOC2A/SNAP29/SYT4/CADPS2/SYT5/SNCA/RIMS2/WNT7A/P2RY1	50
BP	GO:0009048	dosage compensation by inactivation of X chromosome	9/7096	18/18670	0.2085	0.43	0.3205	EIF1/METTL3/YTHDC1/PCGF3/SMCHD1/CDYL/BRCA1/RLIM/UPF1	9
BP	GO:0016446	somatic hypermutation of immunoglobulin genes	9/7096	18/18670	0.2085	0.43	0.3205	UNG/SAMHD1/PMS2P5/MLH1/POLL/EXO1/PMS2P3/MCM3AP/POLB	9
BP	GO:0031065	positive regulation of histone deacetylation	9/7096	18/18670	0.2085	0.43	0.3205	PINK1/BCL6/TGFB1/ZBTB7B/VEGFA/LRRK2/AKAP8/PRKD2/JDP2	9
BP	GO:0034375	high-density lipoprotein particle remodeling	9/7096	18/18670	0.2085	0.43	0.3205	APOC1/SCARB1/CETP/APOE/ABCA5/LCAT/ABCG1/APOA1/ALB	9
BP	GO:0035994	response to muscle stretch	9/7096	18/18670	0.2085	0.43	0.3205	SLC8A1/FOS/NFKBIA/SLC9A1/NFKB1/RELA/DMD/RAF1/CAV3	9
BP	GO:0045056	transcytosis	9/7096	18/18670	0.2085	0.43	0.3205	FCGRT/RAB11A/PTAFR/LRPAP1/AGER/LRP1/MFSD2A/RAB5A/PICALM	9
BP	GO:0051895	negative regulation of focal adhesion assembly	9/7096	18/18670	0.2085	0.43	0.3205	LRP1/ARHGAP6/BCAS3/MMP14/DMTN/CORO1C/CLASP2/RCC2/ITGB1BP1	9
BP	GO:0097094	craniofacial suture morphogenesis	9/7096	18/18670	0.2085	0.43	0.3205	TGFB1/RAB23/MEGF8/TIFAB/BMP4/MMP14/INSIG1/TGFB3/MMP16	9
BP	GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	9/7096	18/18670	0.2085	0.43	0.3205	ZFP36/TOB1/AGO2/BTG2/TNRC6B/TNRC6A/CPEB3/CNOT7/ZFP36L2	9
BP	GO:2000047	regulation of cell-cell adhesion mediated by cadherin	9/7096	18/18670	0.2085	0.43	0.3205	MAD2L2/WNT5A/FLOT1/ADAM19/RGCC/VEGFA/PPM1F/DENND6A/SERPINF2	9
BP	GO:2000479	regulation of cAMP-dependent protein kinase activity	9/7096	18/18670	0.2085	0.43	0.3205	ATP2B4/PRKAR2B/RAPGEF2/PKIB/SIRT1/ADRB2/MST1/PKIA/SESN2	9
BP	GO:0010677	negative regulation of cellular carbohydrate metabolic process	19/7096	42/18670	0.2086	0.43	0.3205	CBFA2T3/FBP1/STAT3/SIK1/COX11/NUPR1/GSK3B/PPARGC1A/MYOG/PFKFB1/INPP5K/HDAC4/PLEK/DDIT4/SERPINA12/MST1/PPARA/C1QTNF3/FAM3A	19
BP	GO:0010907	positive regulation of glucose metabolic process	19/7096	42/18670	0.2086	0.43	0.3205	IGF1/PTPN2/PMAIP1/SLC45A3/KAT2B/DYRK2/PPP1R3E/INSR/DDB1/SIRT1/DGAT2/IRS2/PPARGC1A/SLC25A12/PPARA/KAT2A/ESRRB/GCG/WDR5	19
BP	GO:1901031	regulation of response to reactive oxygen species	19/7096	42/18670	0.2086	0.43	0.3205	GCH1/PINK1/PSAP/TNF/HGF/CD36/BMP7/LRRK2/MIR34A/NFE2L2/DHFR/TXN/SESN1/NR4A3/PDE8A/MET/ENDOG/SESN2/FOXO3	19
BP	GO:2001222	regulation of neuron migration	19/7096	42/18670	0.2086	0.43	0.3205	STAT3/LRIG2/FLNA/PLAA/PLXNB2/RAPGEF2/PHACTR1/NRG1/SRGAP2C/ARHGEF2/ZNF609/SRGAP2/KIF20B/CAMK2A/NSMF/ULK4/RELN/CX3CL1/CAMK2B	19
BP	GO:0001676	long-chain fatty acid metabolic process	46/7096	109/18670	0.2094	0.4314	0.3216	ALOX5/SLC27A1/SLC27A3/PTGS2/ACAA1/ACOT7/ACSL5/GSTP1/MGLL/ELOVL5/SCP2/AKR1C3/PNPLA3/CYP1B1/HPGD/MYO5A/CYP2J2/ACSL4/CYP2S1/AIG1/ACOX1/SLC27A2/HSD17B4/GSTA1/GPX4/PNPLA8/PTGES3/ACSL6/ALOX15B/DAGLB/PAM/CYP2D6/CYP1A2/CPT1A/HPGDS/GSTM4/ELOVL6/CYP4F3/ABCD1/CYP2A6/PLP1/CYP2C8/FADS2/PTGS1/CYP2U1/ACOT8	46
BP	GO:0051261	protein depolymerization	46/7096	109/18670	0.2094	0.4314	0.3216	STMN1/MAP1S/CIB1/MICAL1/TMOD3/LIMA1/TWF2/RDX/CFL2/CAPZA2/SYNJ1/SWAP70/STMN3/CAPG/MICAL2/ARHGEF2/CAPZA1/SH3BP1/SPTBN1/KIF2A/DNAJC6/SH3GL1/AVIL/KIF24/CFL1/CKAP5/TRIOBP/ADD3/PLEK/VPS4B/SEMA5A/DMTN/CLASP2/LMOD3/SCIN/MAP1A/KIF2C/KATNB1/SPTA1/SPTBN2/NAV3/TRPV4/NCKAP5L/TTBK2/SLN/FGF13	46
BP	GO:1902803	regulation of synaptic vesicle transport	36/7096	84/18670	0.2095	0.4315	0.3217	APBA1/PINK1/RAP1B/GSK3B/STXBP1/UNC13B/FBXL20/CDK5/RAB3GAP1/DTNBP1/RAP1A/PREPL/LRRK2/ADCY1/P2RX1/ADORA2B/VPS18/NAPA/RAB5A/CAMK2A/CHRM2/DNM1L/CHRNA4/ATP2A2/DVL1/FMR1/RAB3A/CHRNB2/P2RY4/SYT9/SYT1/VAMP1/SYT4/RIMS2/WNT7A/P2RY1	36
BP	GO:0006497	protein lipidation	38/7096	89/18670	0.2099	0.432	0.3221	ATG7/ZDHHC20/NMT2/PIGV/PIGP/ABHD17C/PIGK/ZDHHC9/PIGN/RAB3GAP1/ABCA1/ZDHHC6/WIPI1/PIGF/PIGB/DPM1/ZDHHC5/GPAA1/PIGM/MPPE1/HHAT/PIGQ/WDR45B/ZDHHC16/PIGO/UGCG/PIGH/ZDHHC14/DPM3/ZDHHC2/ZDHHC18/PIGT/CLIP3/ZDHHC12/ZDHHC21/PGAP3/PGAP1/ATG12	38
BP	GO:0000726	non-recombinational repair	40/7096	94/18670	0.21	0.432	0.3221	USP51/MAD2L2/PARP9/BARD1/UBE2N/ERCC4/ZBTB7A/RNF138/UIMC1/SETMAR/KDM2A/HERC2/XRCC5/SMCHD1/NUDT16L1/SUMO1/ATM/XRCC4/DTX3L/KAT5/RAD52/MLH1/XRCC1/PARP3/ERCC1/LIG4/KDM4D/DCLRE1A/POLL/BRCA1/XRCC6/DCLRE1C/POLA1/PRPF19/REXO4/LIG3/POLB/BRCC3/AUNIP/PAXIP1	40
BP	GO:0070167	regulation of biomineral tissue development	40/7096	94/18670	0.21	0.432	0.3221	SLC8A1/ACVR2B/S1PR1/ATRAID/CEBPB/P2RX7/ATF4/TGFB1/HIF1A/PTK2B/FZD9/BMP2/LTBP3/ISG15/HEY1/TRPM4/BMP7/BCOR/BMPR1A/BMP4/ADRB2/ZMPSTE24/HEY2/KL/SRGN/CYP27B1/TGFB3/BMP2K/MGP/WNT6/NBR1/ROCK2/TMEM119/FGF23/WNT10B/GJA1/GREM1/BMPR1B/MEF2C/BMPR2	40
BP	GO:0008206	bile acid metabolic process	21/7096	47/18670	0.2126	0.4371	0.3258	STARD4/CYP27A1/ACAA1/PANK2/OSBPL9/SCP2/OSBPL1A/LEP/AKR1C1/SLC27A2/HSD17B4/ATP8B1/ACOX2/SIRT1/ARV1/CH25H/OSBPL2/ABCB11/CYP46A1/NR1H4/ACOT8	21
BP	GO:0014911	positive regulation of smooth muscle cell migration	21/7096	47/18670	0.2126	0.4371	0.3258	IGF1/PAK1/P2RY6/AIF1/CCL5/LRP1/CRK/PDGFB/DOCK5/NRP1/BCL2/HDAC4/ITGA2/FOXO4/LPAR1/MDM2/NR4A3/ATP7A/TERT/SSH1/PDGFD	21
BP	GO:0031952	regulation of protein autophosphorylation	21/7096	47/18670	0.2126	0.4371	0.3258	GPNMB/CHP1/NLRP12/PTPRC/RAP2C/PDGFC/VEGFA/RAP2B/MVP/TOM1L1/PDGFB/PPP2R5C/TNKS1BP1/GFRA2/PDGFA/IMPACT/PPP2R5B/MOB1B/ENG/GREM1/PDGFD	21
BP	GO:0006401	RNA catabolic process	159/7096	397/18670	0.2128	0.4372	0.326	MYD88/RNASE2/ZFP36/PPP2CA/SLC11A1/VIM/PSMB9/TOB1/PSMB8/ZC3H14/NUP214/RNASEH2B/AGO2/DIS3L/PSMA5/PSMD11/YTHDF3/MOV10/TNPO1/HNRNPR/METTL14/GIGYF2/SECISBP2/PSME1/BTG2/RNPS1/THRAP3/PAIP1/SMG8/SND1/MAGOHB/RNASE3/FASTKD1/PSMB10/HSPB1/PSMA1/PSMA4/ISG20/PRKCD/LSM5/METTL3/XRN2/HELZ2/NAF1/SAMD4B/NPM1/PSMB1/ZPR1/RBM8A/PSMC4/RNASE6/DEDD2/DHX9/DCP1B/RPL8/DCP2/OAS2/PSMD13/ZC3H12D/PSMB3/RPS24/SLFN13/MRTO4/PUM2/PSMB5/LSM7/PSMD6/RPS21/RNASEH1/ATM/GSPT2/MTPAP/TNKS1BP1/RPS9/DCPS/ZC3HAV1/PSMC3/RPS19/SCGB1A1/FTO/HNRNPC/PSME3/GTPBP1/MLH1/XRN1/MAPKAPK2/EXOSC2/PSMC6/HNRNPA0/CNOT4/EDC4/AGO1/ETF1/RNASEL/CSDC2/UBC/TNRC6B/EXOSC7/TNRC6A/HNRNPD/CPEB3/YBX3/TTC37/HNRNPM/POLR2D/TBRG4/CNOT7/SSB/FMR1/RNASEH2C/SUPV3L1/PSMC1/ZFP36L2/EIF4G1/RPL24/DXO/PSMD8/RPS16/DIS3L2/RPS12/PSMA2/EXOSC9/VIP/EXOSC3/PCID2/SET/CNOT10/RPL32/PSMC5/DROSHA/PSMC2/PSMB2/PSMD4/MTOR/ERN1/SAMD4A/EXOSC6/PNPT1/SIDT2/TIRAP/SKIV2L/EXOSC8/PSMD1/NUDT16/ROCK2/CSDE1/PSMB4/NBAS/SYNCRIP/BOLL/TARDBP/PRKCA/FEN1/PSMD9/PSMD3/EXOSC5/PLEKHN1/UPF1/RPL10A	159
BP	GO:0006362	transcription elongation from RNA polymerase I promoter	14/7096	30/18670	0.2134	0.4374	0.3261	ERCC6/CCNH/POLR2L/TAF1B/POLR2H/GTF2H4/TAF1D/POLR1C/POLR2F/POLR2K/ERCC2/TAF1C/TBP/CD3EAP	14
BP	GO:0021772	olfactory bulb development	14/7096	30/18670	0.2134	0.4374	0.3261	SKI/WNT5A/ATF5/EXT1/SRF/LRRK2/ARX/ID2/SLIT2/NR2E1/CSF1R/EFNA2/AGTPBP1/KIF14	14
BP	GO:0034472	snRNA 3'-end processing	14/7096	30/18670	0.2134	0.4374	0.3261	INTS5/INTS7/TOE1/USB1/INTS8/EXOSC2/EXOSC7/INTS2/EXOSC9/EXOSC3/EXOSC6/EXOSC8/INTS6/EXOSC5	14
BP	GO:0036258	multivesicular body assembly	14/7096	30/18670	0.2134	0.4374	0.3261	STAM/RAB11A/VPS37B/CHMP4B/VPS37C/VTA1/CHMP2A/TSG101/IST1/HGS/CHMP1A/VPS4B/VPS25/CHMP1B	14
BP	GO:0046596	regulation of viral entry into host cell	14/7096	30/18670	0.2134	0.4374	0.3261	FCN1/IFITM2/IFITM1/CD74/IFITM3/PTX3/TRIM26/TRIM11/TRIM21/LGALS1/LGALS9/MID2/CD4/APCS	14
BP	GO:0048873	homeostasis of number of cells within a tissue	14/7096	30/18670	0.2134	0.4374	0.3261	CCR2/LIPA/P2RX7/GIGYF2/KRAS/CORO1A/FLT3LG/IL20RB/IL7/BCL2/FH/BAX/F2R/SMO	14
BP	GO:0090314	positive regulation of protein targeting to membrane	14/7096	30/18670	0.2134	0.4374	0.3261	ITGAM/FYN/CHP1/CIB1/C2CD5/MIEF1/FIS1/PAK1/CDK5/HRAS/MYO1C/CEMIP/CACNB3/ITGB1BP1	14
BP	GO:1905476	negative regulation of protein localization to membrane	14/7096	30/18670	0.2134	0.4374	0.3261	CSK/GBP1/TGFB1/FZD9/GOPC/GDI1/NUMB/INPP5K/RHOQ/DMTN/PID1/AP2M1/ITGB1BP1/PICALM	14
BP	GO:0003179	heart valve morphogenesis	23/7096	52/18670	0.2157	0.4417	0.3293	NOTCH2/DCHS1/TGFB1/BMP2/HEY1/BMPR1A/BMP4/NFATC1/OLFM1/FGFRL1/HEY2/SLIT2/MDM2/SNAI1/RB1/MTOR/SOX4/ROCK2/ADAMTS9/MEF2C/BMPR2/SLIT3/STRA6	23
BP	GO:0009620	response to fungus	23/7096	52/18670	0.2157	0.4417	0.3293	S100A9/S100A8/S100A12/CLEC7A/BCL10/IL17RA/GAPDH/TGFB1/PTX3/TLR4/CRK/COTL1/HAMP/IL25/HRG/GNLY/C10orf99/CTSG/MALT1/BAK1/MPO/IL17RC/FAM3A	23
BP	GO:2000677	regulation of transcription regulatory region DNA binding	23/7096	52/18670	0.2157	0.4417	0.3293	KLF4/IGF1/MAD2L2/DDRGK1/FBXW7/PER2/DOT1L/ZBTB7A/TGFB1/SIN3A/ENHO/TRAF6/NSD1/ZNF593/HEY1/SRI/ZMPSTE24/HEY2/PSEN1/IFNG/RB1/MSX1/TRIM6	23
BP	GO:0046425	regulation of JAK-STAT cascade	57/7096	137/18670	0.2162	0.4425	0.3299	IGF1/FYN/SOCS3/LYN/PPP2CA/PARP9/AKR1B1/STAT3/PTPN2/ADIPOR1/CD40/JAK2/PTPRC/IL15/TNF/ERCC6/DOT1L/HCLS1/CYP1B1/PTK2B/LEP/FLT3/CDK5/NLK/PTK6/CCL5/TNFRSF18/IL6ST/IL6/HDAC2/CLCF1/IFNK/OSM/HGS/DAB1/CD300A/INPP5F/HES1/F2R/PWP1/CNTF/CNOT7/IL18/SOCS1/IL3/TSLP/IFNG/TNFSF18/RET/IL12B/CSF1R/ARL2BP/GHR/IL26/SOCS2/IL23A/MIR146A	57
BP	GO:0001881	receptor recycling	16/7096	35/18670	0.2203	0.4506	0.3359	ARAP1/ECE1/ALS2/VAMP3/LAMTOR1/RAB29/KIF16B/TRAT1/INPP5F/ANXA2P2/PSEN1/LMTK2/EHD3/OPTN/ANXA2/SNCA	16
BP	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	16/7096	35/18670	0.2203	0.4506	0.3359	DDRGK1/HFE/FHIT/RYBP/SGTA/SDCBP/UCHL5/KLHL40/USP7/MAP1A/UBXN1/OGT/HSP90AB1/CLEC16A/BAG5/SMARCC1	16
BP	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	16/7096	35/18670	0.2203	0.4506	0.3359	PMAIP1/YWHAH/GSK3B/SFN/CASP8/CHCHD10/MAPK8/BCL2/BAX/GZMB/YWHAQ/YWHAE/BAD/PPP1R13B/YWHAG/BAK1	16
BP	GO:0031109	microtubule polymerization or depolymerization	47/7096	112/18670	0.2205	0.4507	0.336	STMN1/MAP1S/CIB1/PSRC1/PAK1/CLIP1/RANBP9/CSNK1D/STMN3/ABL1/CDK5RAP2/ARHGEF2/MAPRE1/SKA2/TPPP3/RAC1/MAPRE2/KIF2A/CDH5/ZNF207/MAP7D3/KIF24/CDKN1B/TUBGCP3/CKAP5/NDEL1/RANGRF/SLC39A12/TUBG2/CLASP2/TUBGCP5/CAV3/TUBB4A/MAP1A/KIF2C/KATNB1/SLAIN2/NAV3/TRPV4/SNCA/CLIP3/NCKAP5L/TTBK2/MET/FGF13/TPPP/SKA3	47
BP	GO:0098869	cellular oxidant detoxification	43/7096	102/18670	0.2217	0.452	0.337	NQO1/S100A9/GCH1/ALOX5AP/SOD1/PTGS2/MGST2/GSTP1/TNF/GSR/APOE/TXNRD1/GPX7/CD36/PRDX1/TXNDC17/HBB/CAT/GSTO1/GSTZ1/GPX3/IPCEF1/GSTA1/BMP7/GPX4/MGST1/PRDX6/HBQ1/NFE2L2/DHFR/TXN/SESN1/MGST3/ATP7A/HP/GPX1/SRXN1/HBE1/MPO/NNT/SESN2/PTGS1/ALB	43
BP	GO:0035019	somatic stem cell population maintenance	31/7096	72/18670	0.2218	0.452	0.337	KLF4/SPI1/SKI/RBPJ/STAT3/KLF10/SMAD2/LDB1/ASCL2/PAX8/POLR2L/RAF1/BMP7/BCL9L/POLR2H/LIG4/POLR2F/HES1/POLR2D/VPS72/POLR2K/ZFP36L2/HNF1B/ELF5/NR2E1/FOXP1/SOX4/WNT7A/POLR2I/ZSCAN10/LBH	31
BP	GO:1903556	negative regulation of tumor necrosis factor superfamily cytokine production	31/7096	72/18670	0.2218	0.452	0.337	IGF1/PTPN6/IL27RA/ACP5/ARG2/GPNMB/SYT11/TNFAIP3/GSTP1/IRAK3/LILRB1/SLAMF1/AXL/TLR4/PTPN22/CACTIN/DICER1/AKAP8/GPR18/CD274/LGALS9/TREM2/HAVCR2/CD34/LBP/CD33/C5AR2/CX3CL1/NR1H4/NLRC3/GHRL	31
BP	GO:0014020	primary neural tube formation	41/7096	97/18670	0.2221	0.452	0.337	VASP/BCL10/SKI/WNT5A/TSC1/IFT172/DVL2/PRKACB/IFT57/ZEB2/PLXNB2/TGFB1/TULP3/PFN1/HIF1A/TRAF6/FUZ/CASP3/ABL1/SEMA4C/BMP7/GLMN/BBS4/BMP5/BMP4/KDM2B/KIF20B/CFL1/PRKACA/SPINT1/MKS1/TEAD2/FZD1/DVL1/KAT2A/CTHRC1/PHACTR4/FZD2/GRHL3/PTCH1/GRHL2	41
BP	GO:0015908	fatty acid transport	41/7096	97/18670	0.2221	0.452	0.337	SLC27A1/ANXA1/PLA2G12A/SLC27A3/FABP4/SLCO3A1/PPARD/MIF/SLC25A20/PLIN2/P2RX7/APOE/CPT2/ABCD3/CD36/LEP/ACSL4/IL1B/SLC27A2/ACACB/TNFRSF11A/FABP3/IRS2/PNPLA8/MFSD2A/PLA2G3/PRKAG2/NCOR1/NMUR2/CPT1A/GOT2/PPARA/NMB/SLC5A8/PLA2G6/ABCC4/CROT/ABCD1/SPX/THRSP/NTSR1	41
BP	GO:0042775	mitochondrial ATP synthesis coupled electron transport	41/7096	97/18670	0.2221	0.452	0.337	PINK1/UQCRC2/UQCR11/NDUFA8/NDUFC1/ISCU/NDUFB11/NDUFS3/NDUFA3/NDUFA11/UQCR10/COX7C/COX7A2L/NDUFA4/COX4I2/NDUFA1/COQ9/COX15/NDUFA10/NDUFB1/NDUFB5/UQCRQ/NDUFS1/NDUFB8/DNAJC15/NDUFB6/NDUFB3/SDHA/NDUFS7/NDUFV2/ND4/SDHD/TAZ/SNCA/UQCRB/NDUFB2/SDHAF2/COX6C/NDUFS2/NDUFA7/COX7B	41
BP	GO:0006278	RNA-dependent DNA biosynthetic process	33/7096	77/18670	0.2223	0.452	0.337	MAP3K4/RPA1/PKIB/NAF1/HNRNPA1/TEP1/XRCC5/DCP2/NAT10/PTGES3/ATM/TNKS1BP1/MAPKAPK5/NHP2/HNRNPC/XRN1/GAR1/CCT4/FBXO4/CCT8/ATR/MAPK1/TELO2/ACD/CTC1/GNL3L/HSP90AB1/TERT/PRKCQ/POT1/NOP10/PNKP/NEK7	33
BP	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	33/7096	77/18670	0.2223	0.452	0.337	RNASEH2B/AGO2/RPP38/SND1/TSN/RNASE1/PIWIL4/KRI1/LACTB2/RPP25/ELAC1/ABT1/MRPL44/SLFN13/CPSF3/RPP14/RPS21/RNASEH1/DICER1/AGO1/RNASEL/RCL1/RPP40/EXO1/RPPH1/POP7/DROSHA/ERN1/NUDT16/ENDOG/RRS1/FEN1/ENDOV	33
BP	GO:0045833	negative regulation of lipid metabolic process	39/7096	92/18670	0.2224	0.452	0.337	SLC27A1/APPL2/SOD1/ATP1A1/SIRT4/FBXW7/SIK1/APOC1/TNF/AKR1C3/NFKB1/APOE/ENHO/ERLIN1/PIK3IP1/BMP2/IL1B/ERLIN2/ACACB/SIRT1/DGAT2/PDGFB/CRTC3/ORMDL2/SPHK1/BMP5/ORMDL3/SCAP/PDGFA/ACADVL/SERPINA12/INSIG1/BRCA1/PRKAA1/CYP27B1/SNAI1/PIK3CG/LPCAT1/NR1H4	39
BP	GO:0010833	telomere maintenance via telomere lengthening	35/7096	82/18670	0.2225	0.452	0.337	ERCC4/MAP3K4/RPA1/PKIB/NAF1/HNRNPA1/HNRNPA2B1/XRCC5/DCP2/NAT10/PTGES3/ATM/TNKS1BP1/MAPKAPK5/NHP2/HNRNPC/XRN1/GAR1/CCT4/FBXO4/CCT8/ATR/MAPK1/RTEL1/TELO2/ACD/CTC1/GNL3L/HSP90AB1/TERT/PRKCQ/POT1/NOP10/PNKP/NEK7	35
BP	GO:0051279	regulation of release of sequestered calcium ion into cytosol	35/7096	82/18670	0.2225	0.452	0.337	SLC8A1/PTPN6/LYN/DIAPH1/CXCL9/CXCL11/CXCL10/PKD2/TGFB1/PTK2B/MYO5A/CORO1A/P2RY6/ABL1/GSTO1/DMD/SRI/BAX/PRKACA/CYBA/F2R/CAMK2D/CEMIP/CASQ1/CAPN3/CASQ2/HRC/BDKRB1/TMEM38B/LACRT/LIME1/SNCA/CX3CL1/ATP1A2/NTSR1	35
BP	GO:0006112	energy reserve metabolic process	37/7096	87/18670	0.2226	0.452	0.337	IGF1/MYC/PER2/GSK3B/AGL/DYRK2/LEP/PPP1R3E/INSR/GYS1/PPP1R3D/GYG2/PPP1R2/PHKB/IL6ST/IRS2/PCDH12/PHKG1/PGM2/PRKAG2/KHK/INPP5K/PPP1R3B/PPP1R3F/PPP1CC/PPP1CA/GFPT1/KL/PID1/GAA/PYGM/PPP1CB/PYGL/ESRRB/MTOR/GFPT2/G6PC	37
BP	GO:0000715	nucleotide-excision repair, DNA damage recognition	11/7096	23/18670	0.223	0.452	0.337	RAD23B/DDB1/UBC/COPS2/CETN2/DDB2/CUL4B/COPS8/GPS1/RBX1/COPS3	11
BP	GO:0009310	amine catabolic process	11/7096	23/18670	0.223	0.452	0.337	ATP2B4/ALDH7A1/HNMT/SAT1/IDO1/KYNU/HAAO/BHMT/IDO2/CHDH/TDO2	11
BP	GO:0019400	alditol metabolic process	11/7096	23/18670	0.223	0.452	0.337	MYOF/AKR1B1/GK/GALK1/TPI1/PCK2/LEP/COQ3/DGAT2/GK5/SORD	11
BP	GO:0032098	regulation of appetite	11/7096	23/18670	0.223	0.452	0.337	NUCB2/LEP/SCTR/BBS2/MKKS/BBS4/HTR4/PPARA/SPX/NENF/GHRL	11
BP	GO:0034695	response to prostaglandin E	11/7096	23/18670	0.223	0.452	0.337	PTGER4/PTGER2/GNB1/P2RY6/GNG2/AKAP8/TNFSF4/PRKAA1/P2RY4/CCL19/CCR7	11
BP	GO:0042401	cellular biogenic amine biosynthetic process	11/7096	23/18670	0.223	0.452	0.337	SMS/OAZ2/SAT1/OAZ3/ODC1/AZIN1/TPH2/SRM/DBH/AZIN2/AGMAT	11
BP	GO:0042451	purine nucleoside biosynthetic process	11/7096	23/18670	0.223	0.452	0.337	GMPS/ADK/GUK1/IMPDH1/PRTFDC1/NME3/MTAP/NME4/NME1/ADA/ADAL	11
BP	GO:0043576	regulation of respiratory gaseous exchange	11/7096	23/18670	0.223	0.452	0.337	SLC5A3/NR4A2/TSHZ3/FTO/GLS/TLX3/ATP1A2/NLGN2/PBX3/NTSR1/APLN	11
BP	GO:0046129	purine ribonucleoside biosynthetic process	11/7096	23/18670	0.223	0.452	0.337	GMPS/ADK/GUK1/IMPDH1/PRTFDC1/NME3/MTAP/NME4/NME1/ADA/ADAL	11
BP	GO:0060445	branching involved in salivary gland morphogenesis	11/7096	23/18670	0.223	0.452	0.337	TNF/HGF/BMP7/PLXNA1/NRP1/PLXND1/TGM2/PDGFA/BTBD7/DAG1/LAMA1	11
BP	GO:0070977	bone maturation	11/7096	23/18670	0.223	0.452	0.337	IGF1/DCHS1/THBS3/LEP/RYR1/BMP2/XYLT1/SEMA4D/MBTPS2/RHOA/GREM1	11
BP	GO:0072215	regulation of metanephros development	11/7096	23/18670	0.223	0.452	0.337	STAT1/MYC/EGR1/PAX8/BASP1/PDGFB/BMP4/PDGFA/HNF1B/RET/WT1	11
BP	GO:0072337	modified amino acid transport	11/7096	23/18670	0.223	0.452	0.337	SLC22A4/SLC19A2/FOLR2/SLC22A5/SLC7A11/SLC1A4/SLC46A1/SLC5A6/SLC25A32/CTNS/SLC22A16	11
BP	GO:0090343	positive regulation of cell aging	11/7096	23/18670	0.223	0.452	0.337	LMNA/ARG2/KRAS/EEF1E1/HMGA1/SIRT1/HLA-G/YPEL3/MIR34A/KIR2DL4/MIR146A	11
BP	GO:1901889	negative regulation of cell junction assembly	11/7096	23/18670	0.223	0.452	0.337	TNF/LRP1/ARHGAP6/BCAS3/MMP14/DMTN/CORO1C/CLASP2/RCC2/ITGB1BP1/ROCK2	11
BP	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	18/7096	40/18670	0.2254	0.4567	0.3405	CXCL9/CXCL11/CXCL10/PKD2/P2RY6/ABL1/GSTO1/SRI/BAX/F2R/CEMIP/CASQ1/CAPN3/BDKRB1/LACRT/SNCA/CX3CL1/NTSR1	18
BP	GO:0002820	negative regulation of adaptive immune response	20/7096	45/18670	0.229	0.462	0.3444	PTPN6/IL27RA/TNFRSF14/BCL6/SMAD7/IL4R/PTPRC/HFE/LILRB1/IL7R/PPP3CB/HLA-F/IL20RB/ZBTB7B/HLA-G/CR1/PARP3/TNFSF4/HAVCR2/TBX21	20
BP	GO:0031018	endocrine pancreas development	20/7096	45/18670	0.229	0.462	0.3444	DLL1/ANXA1/WNT5A/GSK3B/RFX3/IL6/BMP5/BMP4/PDX1/HES1/CLOCK/GIPR/BAD/ARNTL/MEN1/SOX4/SIDT2/BAK1/PAX4/SMO	20
BP	GO:0070316	regulation of G0 to G1 transition	20/7096	45/18670	0.229	0.462	0.3444	CBX5/EZH2/RYBP/PCGF2/E2F6/RBBP7/MGA/RBBP4/HLA-G/RHNO1/CBX3/RRM2/FOXO4/RING1/BRCA1/EPC1/PHC1/PPP2R5B/YAF2/UXT	20
BP	GO:0001732	formation of cytoplasmic translation initiation complex	8/7096	16/18670	0.2299	0.462	0.3444	EIF3M/EIF3I/EIF2S2/EIF3G/EIF3B/EIF5/EIF3J/EIF3L	8
BP	GO:0002070	epithelial cell maturation	8/7096	16/18670	0.2299	0.462	0.3444	CDKN1A/HIF1A/FEM1B/RFX3/TYMS/TMEM79/TFCP2L1/GJA1	8
BP	GO:0003222	ventricular trabecula myocardium morphogenesis	8/7096	16/18670	0.2299	0.462	0.3444	RBPJ/UBE4B/HEG1/NRG1/BMPR1A/HEY2/ENG/FOXH1	8
BP	GO:0016114	terpenoid biosynthetic process	8/7096	16/18670	0.2299	0.462	0.3444	RBP1/RDH10/AKR1C3/DHRS9/HMGCS1/FDPS/ALDH8A1/CRABP2	8
BP	GO:0019372	lipoxygenase pathway	8/7096	16/18670	0.2299	0.462	0.3444	ALOX5/ALOX5AP/PTGS2/HPGD/GPX4/ALOX15B/PLA2G3/GPX1	8
BP	GO:0030952	establishment or maintenance of cytoskeleton polarity	8/7096	16/18670	0.2299	0.462	0.3444	LMNA/RHOC/RND3/CKAP5/RHOF/KIF2C/MAPKAP1/RHOA	8
BP	GO:0032225	regulation of synaptic transmission, dopaminergic	8/7096	16/18670	0.2299	0.462	0.3444	PINK1/PTGS2/FLOT1/PNKD/TOR1A/CHRNB2/RAB3B/SNCA	8
BP	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation	8/7096	16/18670	0.2299	0.462	0.3444	GMFG/CYFIP1/CORO1B/ARF1/PICK1/WAS/NCKAP1/FCHSD2	8
BP	GO:0042222	interleukin-1 biosynthetic process	8/7096	16/18670	0.2299	0.462	0.3444	AZU1/JAK2/EGR1/AGER/TYROBP/CMA1/IFNG/APP	8
BP	GO:0043252	sodium-independent organic anion transport	8/7096	16/18670	0.2299	0.462	0.3444	SLCO4A1/SLCO3A1/SLCO2B1/SLCO4C1/MFSD10/SLC16A2/SLCO1C1/SLCO1B1	8
BP	GO:0045116	protein neddylation	8/7096	16/18670	0.2299	0.462	0.3444	DCUN1D1/UBE2F/RNF7/DCUN1D5/UBE2M/DCUN1D3/DCUN1D4/RBX1	8
BP	GO:0050711	negative regulation of interleukin-1 secretion	8/7096	16/18670	0.2299	0.462	0.3444	IL1R2/NLRP3/TNFAIP3/NLRP12/SERPINB1/PML/CPTP/APOA1	8
BP	GO:0061158	3'-UTR-mediated mRNA destabilization	8/7096	16/18670	0.2299	0.462	0.3444	ZFP36/MOV10/ZC3H12D/HNRNPD/CPEB3/ZFP36L2/PLEKHN1/UPF1	8
BP	GO:0061684	chaperone-mediated autophagy	8/7096	16/18670	0.2299	0.462	0.3444	ATG7/CTSA/LAMP2/CLU/PLK3/STUB1/EEF1A2/SNCA	8
BP	GO:0070863	positive regulation of protein exit from endoplasmic reticulum	8/7096	16/18670	0.2299	0.462	0.3444	BCAP31/EDEM1/SAR1B/EDEM2/SAR1A/TMEM30A/TM9SF4/SEC16B	8
BP	GO:0071732	cellular response to nitric oxide	8/7096	16/18670	0.2299	0.462	0.3444	AIFM1/MTR/CRK/DNM2/MMP3/HNRNPD/TRAF2/CCNA2	8
BP	GO:0071871	response to epinephrine	8/7096	16/18670	0.2299	0.462	0.3444	ATP2B4/SRD5A1/SLC9A1/PDE4B/PPARGC1A/PRKACA/KCNQ1/SNCA	8
BP	GO:0072109	glomerular mesangium development	8/7096	16/18670	0.2299	0.462	0.3444	EGR1/ACTA2/BMP7/PDGFB/BMP4/CD34/WT1/PDGFD	8
BP	GO:0099116	tRNA 5'-end processing	8/7096	16/18670	0.2299	0.462	0.3444	RPP38/RPP25/RPP14/HSD17B10/SSB/RPP40/POP7/TRMT10C	8
BP	GO:0099170	postsynaptic modulation of chemical synaptic transmission	8/7096	16/18670	0.2299	0.462	0.3444	NRGN/DCC/CYFIP1/PLCB1/FMR1/EIF4E/GHRL/SYNPO	8
BP	GO:1900451	positive regulation of glutamate receptor signaling pathway	8/7096	16/18670	0.2299	0.462	0.3444	CCR2/PINK1/EPHB2/ARC/ADRB2/IFNG/RELN/SHANK3	8
BP	GO:1902992	negative regulation of amyloid precursor protein catabolic process	8/7096	16/18670	0.2299	0.462	0.3444	IGF1/APOE/CLU/FLOT2/ABCA7/PIN1/PICALM/BIN1	8
BP	GO:1905153	regulation of membrane invagination	8/7096	16/18670	0.2299	0.462	0.3444	APPL2/SYT11/RAB31/CD36/ITGA2/CD300A/ABCA7/TREM2	8
BP	GO:1990000	amyloid fibril formation	8/7096	16/18670	0.2299	0.462	0.3444	APOE/CD36/LDLR/CLU/PSEN1/MDM2/APP/IAPP	8
BP	GO:0097035	regulation of membrane lipid distribution	22/7096	50/18670	0.2317	0.4651	0.3468	KCNN4/ATP8B2/ATP8A1/PLSCR1/P2RX7/PRELID1/PRKCD/ATP11B/ATP10A/ABCA1/ATP8B1/ARV1/XKR8/ABCB4/ABCA7/ANO4/SLC4A1/TMEM30A/PLSCR4/TRIAP1/ATP10B/PLSCR2	22
BP	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	22/7096	50/18670	0.2317	0.4651	0.3468	ANXA1/CCND3/MEPCE/RGCC/LSM11/CCND2/RDX/AIF1/CCND1/DDX3X/KMT2E/UBE2E2/CCNE1/ANKRD17/PLCB1/EGFR/ADAM17/MDM2/EIF4G1/MTBP/CUL4B/TERT	22
BP	GO:2000725	regulation of cardiac muscle cell differentiation	22/7096	50/18670	0.2317	0.4651	0.3468	IGF1/DLL1/RBPJ/RGS2/TGFB1/PAK1/NRG1/BMP2/PARP2/CTDP1/G6PD/BMP4/YY1/PPARA/CAV3/KAT2A/HAMP/PIN1/FZD7/MTOR/GREM1/MEF2C	22
BP	GO:0006972	hyperosmotic response	13/7096	28/18670	0.2326	0.4651	0.3468	AKR1B1/HNMT/XRCC5/ARHGEF2/ICOSLG/EFHD1/SLC12A2/MICU1/YBX3/LETM1/XRCC6/TLR3/TRPV4	13
BP	GO:0009065	glutamine family amino acid catabolic process	13/7096	28/18670	0.2326	0.4651	0.3468	ASRGL1/ATP2B4/ARG2/DDAH2/FAH/ALDH4A1/GLUD1/DAO/ADHFE1/GLUD2/PPAT/GLS/GOT2	13
BP	GO:0010894	negative regulation of steroid biosynthetic process	13/7096	28/18670	0.2326	0.4651	0.3468	SOD1/ATP1A1/NFKB1/APOE/ERLIN1/BMP2/ERLIN2/BMP5/SCAP/INSIG1/CYP27B1/SNAI1/NR1H4	13
BP	GO:0021846	cell proliferation in forebrain	13/7096	28/18670	0.2326	0.4651	0.3468	ZEB2/PCM1/NUMB/ARX/DIXDC1/AKNA/DISC1/HOOK3/DCT/NUMBL/CEP120/WNT7A/KIF14	13
BP	GO:0033137	negative regulation of peptidyl-serine phosphorylation	13/7096	28/18670	0.2326	0.4651	0.3468	SMAD7/HGF/NCK1/PAQR3/DMD/PPM1F/BAX/INPP5K/INPP5F/DDIT4/DMTN/PWP1/BAK1	13
BP	GO:0048679	regulation of axon regeneration	13/7096	28/18670	0.2326	0.4651	0.3468	KLF4/RTN4R/GRN/LRIG2/SPP1/MAP2K1/CERS2/LRP1/NDEL1/INPP5F/RTN4RL1/CNTF/KREMEN1	13
BP	GO:0051647	nucleus localization	13/7096	28/18670	0.2326	0.4651	0.3468	SUN2/FHOD1/PCM1/PAFAH1B1/CLMN/PTK2/SYNE2/HOOK3/TMEM201/CAV3/CEP120/TRIM58/BIN1	13
BP	GO:0070076	histone lysine demethylation	13/7096	28/18670	0.2326	0.4651	0.3468	KDM1B/KDM7A/HSF4/KDM2A/KDM4B/KDM2B/KDM8/KDM5B/KDM6B/KDM4D/KDM5C/UBE2B/KDM4A	13
BP	GO:1902668	negative regulation of axon guidance	13/7096	28/18670	0.2326	0.4651	0.3468	WNT5A/SEMA4B/PTPRO/SEMA4A/SEMA4C/SEMA4D/SEMA6B/NRP1/SEMA3B/SEMA5A/SLIT2/SEMA5B/PLXNA3	13
BP	GO:1990776	response to angiotensin	13/7096	28/18670	0.2326	0.4651	0.3468	PTGS2/NFKB1/RELA/PRKCD/AGTRAP/ARID1B/CYBA/CYBB/CAMK2A/NFE2L2/AHCYL1/SLC30A10/ROCK2	13
BP	GO:2000463	positive regulation of excitatory postsynaptic potential	13/7096	28/18670	0.2326	0.4651	0.3468	PTK2B/BAIAP2/ADRB2/SHANK1/DVL1/CACNB3/PRKCZ/RELN/SSH1/RIMS2/WNT7A/NLGN2/SHANK3	13
BP	GO:2001025	positive regulation of response to drug	13/7096	28/18670	0.2326	0.4651	0.3468	PINK1/RETN/CXCL12/ARL6IP1/MIR34A/PSEN1/GALR1/CHRNB2/RAB3B/ENDOG/TACR2/FOXO3/GHRL	13
BP	GO:0051147	regulation of muscle cell differentiation	74/7096	181/18670	0.2336	0.4671	0.3482	IGF1/TRIM32/DLL1/MAPK12/MEF2A/RBPJ/CAPN2/RGS2/SIK1/FLOT1/IL4R/CXCL9/MORF4L2/EZH2/AKAP13/CXCL10/CD53/TGFB1/NFATC3/CTNNA1/PAK1/SRF/NRG1/RBM4/FLT3LG/BMP2/PARP2/ABL1/EHD1/MED28/SIRT1/CTDP1/PDGFB/CDK9/G6PD/MESP1/NLN/MIR34A/MYOG/TARBP2/BCL2/BMP4/NFATC1/ANKRD17/CYP26B1/NFATC2/HDAC4/CTH/YY1/FOXO4/MAMSTR/MMP14/LMOD3/PPARA/CAV3/HEY2/KAT2A/HAMP/SHOX2/MEGF10/PRDM6/MAPK11/PIN1/FZD7/MSX1/MTOR/HDAC5/ENG/PDCD4/TMEM119/GREM1/BOC/MEF2C/MYF6	74
BP	GO:0033260	nuclear DNA replication	26/7096	60/18670	0.2349	0.4692	0.3498	BCL6/MCM6/GINS1/MCM2/GMNN/ZNF830/RPA1/DBF4B/PRIM2/POLD4/DONSON/POLD2/TIPIN/RFC3/PCNA/ZMPSTE24/MCM5/RTEL1/POLD1/POLA1/POLA2/ORC3/POLE4/ATAD5/FEN1/UPF1	26
BP	GO:0046324	regulation of glucose import	26/7096	60/18670	0.2349	0.4692	0.3498	IGF1/PEA15/APPL2/MEF2A/TNF/C2CD5/LEP/INSR/RAP1A/CREBL2/IRS2/RTN2/ITLN1/CLTCL1/GRB10/PRKAG2/RHOQ/RNASEL/NFE2L2/ASPSCR1/ADIPOR2/PID1/TERT/STXBP3/APPL1/KLF15	26
BP	GO:0046794	transport of virus	26/7096	60/18670	0.2349	0.4692	0.3498	NUP62/NMT2/NUP160/NUP214/VPS37B/RAN/NUP85/SEH1L/NUP43/CD209/VPS37C/POM121/NUP88/TSG101/NUP107/UBAP1/UBC/NUP93/NUP205/FMR1/KPNA1/NUP50/TRIM15/KPNB1/POM121C/AAAS	26
BP	GO:0010717	regulation of epithelial to mesenchymal transition	38/7096	90/18670	0.2355	0.4702	0.3505	GLIPR2/MAD2L2/PPP2CA/SMAD7/ADIPOR1/SMAD2/RGCC/EZH2/PBLD/LDLRAD4/TGFB1/LOXL2/FUZ/BMP2/IL1B/SDCBP/BMP7/IL6/ELL3/BCL9L/HDAC2/BMP5/STRAP/ZNF703/BMP4/OLFM1/CLASP2/TCF7L2/TGFB3/SNAI1/TGFB1I1/GCNT2/MTOR/HPN/DAG1/ENG/SDHAF2/GREM1	38
BP	GO:1903035	negative regulation of response to wounding	38/7096	90/18670	0.2355	0.4702	0.3505	SERPINB2/RTN4R/CDKN1A/PROS1/LRIG2/SPP1/TFPI/DUSP10/CERS2/SIGLEC10/APOE/HMGCR/PRKCD/AGER/THBD/CRK/SERPING1/PDGFB/PLAUR/WFDC1/MIR34A/SERPINE1/CDKN1B/INPP5F/RTN4RL1/PDGFA/MYOZ1/CLASP2/ANXA2P2/HRG/CD34/ANXA2/TSPAN8/KREMEN1/GJA1/SERPINF2/APCS/CD109	38
BP	GO:0071826	ribonucleoprotein complex subunit organization	117/7096	291/18670	0.2357	0.4702	0.3505	CELF6/SRSF5/C9orf72/KLC1/DDX20/G3BP2/AGO2/EIF6/SRSF10/CRNKL1/RUVBL2/MTIF2/RUVBL1/YTHDC1/NAF1/EIF2D/COIL/EIF3M/SNRNP200/EIF4B/NPM1/SNUPN/SNRPB/GEMIN6/TXNL4A/DHX9/SRPK2/LUC7L/SFSWAP/GEMIN7/ABT1/EIF3I/EIF2S2/DHX8/EIF4H/EIF2S1/CLP1/ATXN2/CD2BP2/MRTO4/LSM14A/EIF3G/PUM2/PTGES3/DDX3X/BICD1/ATM/MCTS1/SNRPD1/PRPF3/USP4/SETX/DICER1/SNRPC/RRP7A/ISY1/RPS19/ATXN2L/STRAP/TARBP2/NIP7/LUC7L2/SRSF6/SNRPF/RPF2/GFM2/AGO1/DDX1/EIF3B/PRPF8/SF3A3/EIF5/GRB7/SRPK1/TICRR/WEE2-AS1/PRMT5/AAR2/POLR2D/EIF3J/TGS1/PRPF31/DYRK3/C1QBP/CNOT7/ATR/SART1/PRKAA1/LOC100128988/MTIF3/CELF2/WDR77/RPL24/EIF2A/MRPL20/NUFIP1/CLNS1A/KIF5B/HSP90AB1/PRPF19/CELF3/MDN1/VCP/CDC73/PRPF39/ADAR/MPV17L2/MRPS2/CPSF7/ZNHIT6/EIF3L/RPL3L/LUC7L3/RRS1/SNRPG/SNRPD2/MRRF	117
BP	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	28/7096	65/18670	0.2357	0.4702	0.3505	CELF6/TRA2B/NSRP1/SRSF5/KHDRBS1/RNPS1/THRAP3/RBM7/ZBTB7A/SRSF10/MBNL1/RBM4/RBM4B/HNRNPA1/RBM8A/SRSF3/MBNL3/SRSF6/SREK1/SRSF7/FMR1/CELF2/SRSF4/ZC3H10/RBM25/CELF3/SRRM4/SAP18	28
BP	GO:0006026	aminoglycan catabolic process	28/7096	65/18670	0.2357	0.4702	0.3505	FUCA1/HEXB/VCAN/NAGLU/CHP1/IDS/CD44/SLC9A1/HEXA/TGFB1/ARSB/SGSH/HYAL2/GNS/CSPG4/IDUA/CTBS/GUSB/HPSE/HYAL3/PGLYRP4/BCAN/CEMIP/GPC2/STAB2/GPC4/LYVE1/SDC3	28
BP	GO:0034308	primary alcohol metabolic process	36/7096	85/18670	0.236	0.4704	0.3507	IGF1/ALDH3A2/CBR4/AKR1B1/ALDH1A1/GDE1/RDH10/ADH5/RETSAT/AKR1C3/AKR7A2/DHRS3/DHRS9/CYP1B1/AKR1A1/RDH16/NAPEPLD/BMP2/AKR1C1/ALDH2/PLB1/DGAT2/RDH12/BMP5/CYP2D6/CYP1A2/RDH5/CHKA/AKR1B10/ADH1B/SULT1B1/CACNA1H/ADH7/RBP4/PNPLA4/HAO1	36
BP	GO:0048864	stem cell development	36/7096	85/18670	0.236	0.4704	0.3507	HTR2B/FN1/SEMA4B/KLHL12/KITLG/RDH10/PTPRC/ZEB2/HIF1A/NRG1/SEMA4A/SEMA4C/SEMA4D/EFNB1/BMP7/NOLC1/SEMA6B/KBTBD8/BMPR1A/NRP1/SEMA3B/ANXA6/BMP4/NRP2/CFL1/PEF1/SEMA5A/HES1/CORO1C/SEMA5B/MAPK1/RET/MSI2/PHACTR4/WNT7A/SMO	36
BP	GO:0032720	negative regulation of tumor necrosis factor production	30/7096	70/18670	0.2362	0.4707	0.3509	IGF1/PTPN6/IL27RA/ACP5/ARG2/GPNMB/SYT11/TNFAIP3/GSTP1/IRAK3/LILRB1/SLAMF1/AXL/TLR4/PTPN22/CACTIN/DICER1/AKAP8/GPR18/LGALS9/TREM2/HAVCR2/CD34/LBP/CD33/C5AR2/CX3CL1/NR1H4/NLRC3/GHRL	30
BP	GO:0006073	cellular glucan metabolic process	32/7096	75/18670	0.2364	0.4707	0.3509	IGF1/MGAM/PER2/GSK3B/AGL/DYRK2/PPP1R3E/INSR/GYS1/PPP1R3D/GYG2/PPP1R2/PHKB/IL6ST/IRS2/PCDH12/PHKG1/PGM2/PRKAG2/KHK/INPP5K/PPP1R3B/PPP1R3F/PPP1CC/PPP1CA/GAA/PYGM/PPP1CB/PYGL/ESRRB/MTOR/G6PC	32
BP	GO:0044042	glucan metabolic process	32/7096	75/18670	0.2364	0.4707	0.3509	IGF1/MGAM/PER2/GSK3B/AGL/DYRK2/PPP1R3E/INSR/GYS1/PPP1R3D/GYG2/PPP1R2/PHKB/IL6ST/IRS2/PCDH12/PHKG1/PGM2/PRKAG2/KHK/INPP5K/PPP1R3B/PPP1R3F/PPP1CC/PPP1CA/GAA/PYGM/PPP1CB/PYGL/ESRRB/MTOR/G6PC	32
BP	GO:0044706	multi-multicellular organism process	90/7096	222/18670	0.2372	0.4723	0.3521	CRHBP/JUNB/FOS/VDR/NAMPT/HEXB/FOSB/SOD1/ITGA5/AKR1B1/CAPN2/PTGS2/SPP1/PPARD/RGS2/PZP/AGO2/HFE/IGFBP7/KRAS/DAZAP1/TGFB1/MAGED2/PTAFR/HPGD/LEP/EPOR/ACSL4/ARHGDIB/IDO1/IL1B/STOX2/KLK14/CTSB/UBE2A/THBD/IGFBP2/ADCY7/KALRN/ACVR1B/ETS1/SCGB1A1/PAM/EMP2/P2RX1/RXRA/ASH1L/MMP9/BCL2/TIMP1/APOL2/TLE6/ITGA2/PPAT/PCSK5/CTSV/LGALS9/HYAL3/AMBP/ITGA3/GOT2/CALR/STS/C1QBP/ADIPOR2/MAPK1/PSG7/CYP27B1/PLA2G6/TGFB3/HAVCR2/CAD/FOSL1/ARNTL/PTHLH/TFCP2L1/MEN1/MMP2/MTOR/TEKT3/B4GALT1/ACR/GJA1/SYDE1/PSG5/GHRL/PSG4/NRK/BMPR2/PSG11	90
BP	GO:0032633	interleukin-4 production	15/7096	33/18670	0.2391	0.4752	0.3542	RBPJ/NLRP3/CEBPB/IL1RAP/IL20RB/HLA-E/ITK/SCGB1A1/LGALS9/TNFSF4/HAVCR2/PRKCZ/PRKCQ/CD83/CD3E	15
BP	GO:0032691	negative regulation of interleukin-1 beta production	15/7096	33/18670	0.2391	0.4752	0.3542	IGF1/CX3CR1/ACP5/NLRP3/TNFAIP3/GSTP1/SERPINB1/PML/MEFV/CPTP/APOA1/TREM2/CD33/CX3CL1/GHRL	15
BP	GO:0036314	response to sterol	15/7096	33/18670	0.2391	0.4752	0.3542	SMAD2/LRP8/TGFB1/AACS/HMGCS1/ABCA1/CCR5/MLC1/INHBA/NFE2L1/INSIG1/RORA/DAG1/SMO/PTCH1	15
BP	GO:0048536	spleen development	15/7096	33/18670	0.2391	0.4752	0.3542	SLC40A1/NFKB2/CDKN2B/ABL1/CITED2/BCL2L11/BCL2/PPP2R3C/FADD/ADAM17/CDH17/EPB42/PCID2/POLB/BARX1	15
BP	GO:0048821	erythrocyte development	15/7096	33/18670	0.2391	0.4752	0.3542	KLF2/JMJD6/LYAR/BCL6/TMOD3/FAM210B/ZBTB7A/SRF/G6PD/TAL1/DMTN/ERCC2/SLC4A1/EPB42/TRIM58	15
BP	GO:1901890	positive regulation of cell junction assembly	15/7096	33/18670	0.2391	0.4752	0.3542	S100A10/TSC1/FLOT1/VEGFA/ABL1/PPM1F/RAC1/NPHP4/NRP1/HRG/MAP4K4/LIMS1/ITGB1BP1/PTPRJ/FMN1	15
BP	GO:0030856	regulation of epithelial cell differentiation	64/7096	156/18670	0.2419	0.4805	0.3582	VDR/DLL1/ZFP36/S1PR3/KEAP1/STAT1/CEBPB/CBFB/CTSK/TNF/EZH2/GSK3B/ZEB2/TRIM16/NCOA3/VEGFA/SFN/PAX8/IL1B/PTCH2/CDKN1C/SFRP4/RFX3/CCND1/KRT36/CDH5/MESP1/KLF7/MIR34A/ALOX15B/BTG1/MMP9/MAFG/BMP4/SERPINE1/CDKN1B/SRSF6/VEZF1/CTSV/HES1/CDSN/CLOCK/AQP3/HEY2/NOTCH4/CYP27B1/REG3G/BAD/IFNG/ARNTL/DSPP/FOXN1/KRT84/ROCK2/WNT10B/SMO/HOXA7/KIAA1109/CD24/PTCH1/GRHL2/MYCL/GRHL1/CD109	64
BP	GO:1903169	regulation of calcium ion transmembrane transport	62/7096	151/18670	0.2436	0.4826	0.3598	SLC8A1/FYN/PTPN6/LYN/DIAPH1/CXCL9/CXCL11/SLC9A1/CXCL10/PKD2/TGFB1/KCNE3/PTK2B/MYO5A/CORO1A/P2RY6/AHNAK/PDE4B/ABL1/STIM2/GSTO1/PLCG2/DMD/TMC2/G6PD/SUMO1/PSEN2/SRI/BAX/ATP1B1/PRKACA/CYBA/F2R/CAMK2D/CEMIP/CAV3/STAC2/FMR1/GPR35/YWHAE/CASQ1/PLA2G6/CAPN3/CASQ2/HRC/BDKRB1/EHD3/TMEM38B/LACRT/PIK3CG/CACNB3/REM2/OPRL1/LIME1/SNCA/CX3CL1/SLN/TMC1/KCNE2/ATP1A2/BIN1/NTSR1	62
BP	GO:0007190	activation of adenylate cyclase activity	17/7096	38/18670	0.2437	0.4826	0.3598	LGR4/CAP1/ADRB1/RAF1/ADCY7/ADCY1/ADORA2B/ADCY3/ADRB2/GIPR/LGR5/FSHR/RXFP2/CAP2/ADORA3/ACR/AVPR2	17
BP	GO:0035329	hippo signaling	17/7096	38/18670	0.2437	0.4826	0.3598	MOB1A/DCHS1/DVL2/MOB3B/LATS1/CASP3/SAV1/MARK3/NPHP4/TEAD2/WWC2/YWHAE/LATS2/MOB1B/AMOTL1/NEK8/WWC1	17
BP	GO:0046329	negative regulation of JNK cascade	17/7096	38/18670	0.2437	0.4826	0.3598	PINK1/DUSP10/GSTP1/DUSP3/TAOK3/PTPN22/PAFAH1B1/DUSP19/CYLD/NCOR1/ZMYND11/AMBP/HIPK3/DNAJA1/MEN1/PDCD4/AIDA	17
BP	GO:0051590	positive regulation of neurotransmitter transport	17/7096	38/18670	0.2437	0.4826	0.3598	P2RX7/STXBP1/UNC13B/ARL6IP1/CDK5/RAB3GAP1/DTNBP1/DNM1L/PSEN1/SYT9/SYT1/RAB3B/SNX4/SNCA/TACR2/NTSR1/APLN	17
BP	GO:0000470	maturation of LSU-rRNA	10/7096	21/18670	0.2447	0.4826	0.3598	GTPBP4/NHP2/LAS1L/FTSJ3/RPF2/DDX18/RPL7L1/ZNHIT6/MRPL1/RPL10A	10
BP	GO:0000966	RNA 5'-end processing	10/7096	21/18670	0.2447	0.4826	0.3598	RPP38/RPP25/ABT1/RPP14/HSD17B10/SSB/RPP40/POP7/PNPT1/TRMT10C	10
BP	GO:0001956	positive regulation of neurotransmitter secretion	10/7096	21/18670	0.2447	0.4826	0.3598	STXBP1/UNC13B/CDK5/RAB3GAP1/DTNBP1/DNM1L/SYT9/SYT1/SNCA/TACR2	10
BP	GO:0006144	purine nucleobase metabolic process	10/7096	21/18670	0.2447	0.4826	0.3598	ACPP/GMPS/PAICS/DPYD/GMPR2/PRPS1/PPAT/ADA/SHMT1/AOX1	10
BP	GO:0010829	negative regulation of glucose transmembrane transport	10/7096	21/18670	0.2447	0.4826	0.3598	PEA15/APPL2/TNF/LEP/IL1B/GRB10/INPP5K/FABP5/PID1/STXBP3	10
BP	GO:0016553	base conversion or substitution editing	10/7096	21/18670	0.2447	0.4826	0.3598	METTL3/ADARB1/APOBEC3G/APOBEC3C/APOBEC2/RBM47/APOBEC3B/ADAT2/ADAR/NUDT16	10
BP	GO:0032516	positive regulation of phosphoprotein phosphatase activity	10/7096	21/18670	0.2447	0.4826	0.3598	PPP1R15A/JAK2/PTPRC/SLC39A10/PPP1R15B/CD300A/PPP1R14D/HSP90AB1/CD33/MTOR	10
BP	GO:0035357	peroxisome proliferator activated receptor signaling pathway	10/7096	21/18670	0.2447	0.4826	0.3598	ACTN4/STARD10/LEP/SIRT1/CITED2/ALOX15B/RXRA/ASXL2/FABP5/FAM120B	10
BP	GO:0036344	platelet morphogenesis	10/7096	21/18670	0.2447	0.4826	0.3598	PTPN6/CIB1/SRF/ACTN1/NBEAL2/CASP3/VPS33A/TAL1/MYH9/MEF2C	10
BP	GO:0036499	PERK-mediated unfolded protein response	10/7096	21/18670	0.2447	0.4826	0.3598	PTPN2/PPP1R15A/ATF4/HSPA5/NCK1/TMEM33/PPP1R15B/EIF2S1/ASNS/NFE2L2	10
BP	GO:0042135	neurotransmitter catabolic process	10/7096	21/18670	0.2447	0.4826	0.3598	POR/ALDH7A1/HNMT/MAOA/ALDH5A1/BHMT/MAOB/AMT/LRTOMT/CHDH	10
BP	GO:0042402	cellular biogenic amine catabolic process	10/7096	21/18670	0.2447	0.4826	0.3598	ALDH7A1/HNMT/SAT1/IDO1/KYNU/HAAO/BHMT/IDO2/CHDH/TDO2	10
BP	GO:0048026	positive regulation of mRNA splicing, via spliceosome	10/7096	21/18670	0.2447	0.4826	0.3598	TRA2B/DAZAP1/THRAP3/RBMXL1/RBM3/PRDX6/SF3B4/PRPF19/CELF3/HMX2	10
BP	GO:0061003	positive regulation of dendritic spine morphogenesis	10/7096	21/18670	0.2447	0.4826	0.3598	ACTR2/LRP8/BAIAP2/PAFAH1B1/CAPRIN1/KALRN/BHLHB9/DNM1L/RELN/CAMK2B	10
BP	GO:0070584	mitochondrion morphogenesis	10/7096	21/18670	0.2447	0.4826	0.3598	PANK2/FIS1/SSBP1/NUBPL/BAX/DNM1L/PID1/SUPV3L1/PNPT1/OPA3	10
BP	GO:0140058	neuron projection arborization	10/7096	21/18670	0.2447	0.4826	0.3598	WNT5A/DVL2/MOV10/PHACTR1/GRIP1/LRRK2/NRP1/FZD4/DVL1/MAP3K13	10
BP	GO:0140131	positive regulation of lymphocyte chemotaxis	10/7096	21/18670	0.2447	0.4826	0.3598	CCR2/OXSR1/WNT5A/PTK2B/CXCL13/CCL5/CCL7/TMEM102/ADAM17/CCL4	10
BP	GO:2000810	regulation of bicellular tight junction assembly	10/7096	21/18670	0.2447	0.4826	0.3598	CBFB/TNF/GPBAR1/MYO1C/NPHP4/PRKACA/FZD5/SNAI1/ROCK2/GJA1	10
BP	GO:0051983	regulation of chromosome segregation	43/7096	103/18670	0.2462	0.4855	0.362	DUSP1/MAD2L2/DYNC1LI1/SPDL1/CSNK2A2/SMC5/SMC6/CENPE/NAA10/RMI2/KLHL22/CDK5RAP2/NSMCE2/SPAG5/SFPQ/CDC23/ESPL1/ZNF207/PUM2/LCMT1/ATM/ANAPC5/BUB3/NDC80/CTCF/GEN1/ZW10/MOS/CDC26/RCC2/RIOK2/DLGAP5/KIF2C/ANAPC4/MKI67/CDC27/CDC20/PCID2/RB1/ANAPC11/IK/FEN1/HORMAD1	43
BP	GO:0010863	positive regulation of phospholipase C activity	19/7096	43/18670	0.2468	0.4863	0.3625	HTR2B/S1PR4/FLT1/GNA15/PTAFR/GNAQ/LPAR2/P2RY6/HRAS/P2RY12/ITK/ARHGAP6/LPAR1/EGFR/ABL2/TXK/ADCYAP1R1/RASGRP4/NTRK2	19
BP	GO:0032459	regulation of protein oligomerization	19/7096	43/18670	0.2468	0.4863	0.3625	BMF/PMAIP1/RHOC/APOE/AIM2/TMC8/CLU/BCL2L11/BAX/MMP3/MMP1/DNM1L/PEX14/RIOK3/SH3GLB1/OPRD1/IAPP/SNX9/ALB	19
BP	GO:0032881	regulation of polysaccharide metabolic process	19/7096	43/18670	0.2468	0.4863	0.3625	IGF1/NFKB1/GSK3B/DYRK2/TGFB1/PPP1R3E/INSR/PPP1R3D/IRS2/PDGFB/KHK/INPP5K/PPP1R3B/PPP1R3F/AP2A1/PPP1CA/PPP1CB/ESRRB/MTOR	19
BP	GO:0033273	response to vitamin	39/7096	93/18670	0.2484	0.489	0.3646	VDR/CDKN2D/PIM1/PTGS2/SPP1/PPARD/FOLR2/GDAP1/GSTP1/IL15/CXCL10/RELA/TGFB1/HMGCS1/ALAD/LEP/CAT/BMP7/CCND1/KYNU/SPARC/TRIM24/CYP26B1/SETDB1/ITGA2/TYMS/PDX1/ADA/EGFR/DNMT3A/AQP3/HAMP/MDM2/CYP27B1/CD4/CYP26A1/MGMT/FGF23/NNT	39
BP	GO:1901655	cellular response to ketone	39/7096	93/18670	0.2484	0.489	0.3646	KLF4/KLF2/PTGER4/AIFM1/SRD5A1/AKR1B1/PTGER2/SPP1/GNB1/AKR1C3/CDK4/TGFB1/AACS/PCK2/ADAM15/P2RY6/TFAP4/AHR/SIRT1/KLF9/GNG2/SMYD3/ADCY1/DCPS/AKAP8/XRN1/ADCY3/MAP4K1/DDIT4/NPAS4/FDX1/EGFR/TNFSF4/PRKAA1/P2RY4/MSN/EIF4E/ROCK2/FOXO3	39
BP	GO:0032088	negative regulation of NF-kappaB transcription factor activity	37/7096	88/18670	0.2493	0.4906	0.3657	KLF4/NLRP3/CHP1/TNFAIP3/NLRC5/G3BP2/NLRP12/IRAK3/NFKBIA/AIM2/TRIM37/CYP1B1/ARRB1/TRAF3/CAT/CACTIN/CMKLR1/NFKBID/RBCK1/SIRT1/BMP7/CYLD/TRIM21/SETD6/COMMD1/USP7/TAX1BP1/DAP/HAVCR2/PKHD1/MAP2K5/NLRP2/ADORA3/CHUK/NR1H4/NLRC3/BRMS1	37
BP	GO:1903321	negative regulation of protein modification by small protein conjugation or removal	37/7096	88/18670	0.2493	0.4906	0.3657	FYN/MAD2L2/HMG20A/CHP1/SMAD7/TNFAIP3/PER2/PLAA/RELA/GTPBP4/ARRB1/CDK5/ABL1/GCLC/UBR5/ISG15/GLMN/PRR7/USP4/DTX3L/TRIM21/IVNS1ABP/KLHL40/PIAS3/SPOPL/BAG2/PSEN1/CAPN3/UBXN1/OGT/DNAJA1/GNL3L/MTOR/HMG20B/SOX4/BAG5/RASD2	37
BP	GO:0035065	regulation of histone acetylation	23/7096	53/18670	0.2503	0.4922	0.3669	SPI1/TGFB1/SIN3A/ZNF451/ARRB1/RUVBL2/KAT7/SETD5/IL1B/SIRT1/PPARGC1A/FLCN/MUC1/NOC2L/CTCF/ZMPSTE24/BRCA1/KAT2A/EID1/SET/SNCA/PAXIP1/TAF7	23
BP	GO:0071320	cellular response to cAMP	23/7096	53/18670	0.2503	0.4922	0.3669	CRHBP/SLC8A1/EZR/AQP9/SRD5A1/RAP1B/PKD2/PTAFR/RAPGEF2/HSPA5/RAP1A/AHR/HCN4/INPP5K/KCNQ1/DMTN/FDX1/PIK3CG/APP/HCN1/SLC8A3/WNT10B/WT1	23
BP	GO:1901185	negative regulation of ERBB signaling pathway	23/7096	53/18670	0.2503	0.4922	0.3669	STAM/PTPN2/NUP62/LGMN/DUSP3/CBLB/SOCS5/ZFYVE28/ZGPAT/RNF115/SNX6/RNF126/TSG101/HGS/GRB2/SPRY1/VPS25/EGFR/SPRY2/PSEN1/SNX5/HBEGF/PTPRJ	23
BP	GO:0010827	regulation of glucose transmembrane transport	33/7096	78/18670	0.2508	0.4927	0.3673	IGF1/PEA15/APPL2/MEF2A/TNF/C2CD5/LEP/INSR/IL1B/RAP1A/CREBL2/IRS2/RTN2/ITLN1/CLTCL1/GRB10/PRKAG2/INPP5K/RHOQ/FFAR4/RNASEL/NFE2L2/FABP5/ASPSCR1/ADIPOR2/PID1/NR4A3/TERT/STXBP3/CLIP3/APPL1/KLF15/STXBP4	33
BP	GO:0030837	negative regulation of actin filament polymerization	25/7096	58/18670	0.2512	0.4927	0.3673	MYADM/TMSB10/TMOD3/TWF2/RDX/PFN1/CAPZA2/PRKCD/ARFGEF1/CAPG/CAPZA1/MKKS/SPTBN1/BBS4/AVIL/KANK1/TRIOBP/ADD3/DMTN/LMOD3/SCIN/SLIT2/SPTA1/SPTBN2/KANK3	25
BP	GO:0055081	anion homeostasis	25/7096	58/18670	0.2512	0.4927	0.3673	SLC7A11/CETP/APOE/XPR1/ABCA1/SLC12A9/SFRP4/SIRT1/DGAT2/FABP3/SLC12A2/SLC12A8/ABCG1/PRKAA1/APOA1/POLD1/SLC12A1/SLC12A7/ATP6V1B1/ABCD1/SLC12A4/GCM2/FGF23/NR1H4/SLC12A6	25
BP	GO:0060997	dendritic spine morphogenesis	25/7096	58/18670	0.2512	0.4927	0.3673	SIPA1L1/DNM3/DOCK10/EPHB2/ACTR2/LRP8/UBE3A/BAIAP2/CDK5/PAFAH1B1/CAPRIN1/KALRN/LRRK2/ARC/PDLIM5/CFL1/SHANK1/BHLHB9/DNM1L/DVL1/EPHB1/RELN/WNT7A/SHANK3/CAMK2B	25
BP	GO:0031646	positive regulation of neurological system process	27/7096	63/18670	0.2515	0.4927	0.3673	RNF10/UNC13B/HGF/PTAFR/PTK2B/BAIAP2/S100B/ZNF488/CST7/DICER1/SLC25A12/ADRB2/ITGA2/SHANK1/DVL1/CACNB3/PRKCZ/OPRL1/RELN/MTOR/DAG1/SSH1/RIMS2/WNT7A/NLGN2/SHANK3/NTSR1	27
BP	GO:0010812	negative regulation of cell-substrate adhesion	29/7096	68/18670	0.2515	0.4927	0.3673	GBP1/BCL6/ACTN4/PTPRO/ADAM15/MMP12/LRP1/ARHGAP6/SERPINE1/BCAS3/KANK1/LGALS1/MMP14/DMTN/CORO1C/CLASP2/RCC2/FZD4/WNT1/SPOCK1/GCNT2/FZD7/TACSTD2/MEN1/MAP4K4/RHOA/CX3CL1/ITGB1BP1/HOXA7	29
BP	GO:0035914	skeletal muscle cell differentiation	29/7096	68/18670	0.2515	0.4927	0.3673	HIVEP3/FOS/KLHL41/EGR1/NUPR1/BTG2/EMD/UQCC2/NR1D2/S100B/EGR2/BCL9L/NLN/MYOG/CYP26B1/KLF5/KLHL40/COPS2/MEGF10/EPHB1/ARNTL/HLF/RB1/ZNF689/HMG20B/PAX7/PAX5/MEF2C/MYF6	29
BP	GO:0046323	glucose import	29/7096	68/18670	0.2515	0.4927	0.3673	IGF1/PEA15/APPL2/MEF2A/TSC1/TNF/C2CD5/LEP/INSR/RAP1A/CREBL2/IRS2/RTN2/ITLN1/CLTCL1/GRB10/PRKAG2/RHOQ/RNASEL/NFE2L2/ASPSCR1/ADIPOR2/PID1/HNF1A/TERT/STXBP3/APPL1/KLF15/SESN2	29
BP	GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin	12/7096	26/18670	0.2539	0.4927	0.3673	CTSZ/ATP6AP2/CPA3/PCSK5/CYBA/F2R/CMA1/SUCNR1/CTSG/REN/RHOA/SERPINF2	12
BP	GO:0021591	ventricular system development	12/7096	26/18670	0.2539	0.4927	0.3673	MBOAT7/SLC7A11/RAPGEF2/DPCD/AK8/NUMB/TSKU/BBS4/KDM2B/KIF27/NUMBL/PAX5	12
BP	GO:0022011	myelination in peripheral nervous system	12/7096	26/18670	0.2539	0.4927	0.3673	MPP5/SKI/SOD1/NRG1/NDRG1/DICER1/ADAM22/SH3TC2/LGI4/DAG1/NTRK2/POU3F1	12
BP	GO:0032292	peripheral nervous system axon ensheathment	12/7096	26/18670	0.2539	0.4927	0.3673	MPP5/SKI/SOD1/NRG1/NDRG1/DICER1/ADAM22/SH3TC2/LGI4/DAG1/NTRK2/POU3F1	12
BP	GO:0032366	intracellular sterol transport	12/7096	26/18670	0.2539	0.4927	0.3673	STARD4/NPC2/SCP2/ABCA1/LDLR/ARV1/ABCG1/OSBPL2/NUS1/ANXA2P2/SERAC1/ANXA2	12
BP	GO:0032367	intracellular cholesterol transport	12/7096	26/18670	0.2539	0.4927	0.3673	STARD4/NPC2/SCP2/ABCA1/LDLR/ARV1/ABCG1/OSBPL2/NUS1/ANXA2P2/SERAC1/ANXA2	12
BP	GO:0032800	receptor biosynthetic process	12/7096	26/18670	0.2539	0.4927	0.3673	JAK2/TNF/HIF1A/HNRNPK/FURIN/HDAC2/SCAP/NR1H3/PPARA/IFNG/SEC24A/CNPY2	12
BP	GO:0051125	regulation of actin nucleation	12/7096	26/18670	0.2539	0.4927	0.3673	GMFG/CORO1A/ARPIN/CYFIP1/CORO1B/ARF1/SCIN/PICK1/WAS/NCKAP1/FCHSD2/FMN1	12
BP	GO:0055083	monovalent inorganic anion homeostasis	12/7096	26/18670	0.2539	0.4927	0.3673	XPR1/SLC12A9/SFRP4/SLC12A2/SLC12A8/SLC12A1/SLC12A7/ATP6V1B1/SLC12A4/GCM2/FGF23/SLC12A6	12
BP	GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	12/7096	26/18670	0.2539	0.4927	0.3673	PMAIP1/YWHAH/SFN/CASP8/MAPK8/BCL2/GZMB/YWHAQ/YWHAE/BAD/PPP1R13B/YWHAG	12
BP	GO:1900740	positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	12/7096	26/18670	0.2539	0.4927	0.3673	PMAIP1/YWHAH/SFN/CASP8/MAPK8/BCL2/GZMB/YWHAQ/YWHAE/BAD/PPP1R13B/YWHAG	12
BP	GO:0001771	immunological synapse formation	7/7096	14/18670	0.2546	0.4927	0.3673	DOCK8/PRF1/MSN/HAVCR2/EPHB1/CCL19/CCR7	7
BP	GO:0006241	CTP biosynthetic process	7/7096	14/18670	0.2546	0.4927	0.3673	CTPS2/NME3/NME4/NME1/UCK1/CTPS1/UCKL1	7
BP	GO:0006268	DNA unwinding involved in DNA replication	7/7096	14/18670	0.2546	0.4927	0.3673	MCM6/MCM2/RPA1/PURA/HMGA1/RECQL/RECQL4	7
BP	GO:0007100	mitotic centrosome separation	7/7096	14/18670	0.2546	0.4927	0.3673	NUP62/KIF3B/UBXN2B/NSFL1C/NDEL1/AURKA/CEP85	7
BP	GO:0010755	regulation of plasminogen activation	7/7096	14/18670	0.2546	0.4927	0.3673	ENO1/CTSZ/SERPINE1/ANXA2P2/ANXA2/HPN/SERPINF2	7
BP	GO:0014841	skeletal muscle satellite cell proliferation	7/7096	14/18670	0.2546	0.4927	0.3673	STAT3/PPARD/JAK2/PAXBP1/MYOG/MEGF10/EPHB1	7
BP	GO:0014854	response to inactivity	7/7096	14/18670	0.2546	0.4927	0.3673	PKM/CAT/MYOG/MTMR4/HDAC4/CASQ1/DAG1	7
BP	GO:0030213	hyaluronan biosynthetic process	7/7096	14/18670	0.2546	0.4927	0.3673	ABCC5/NFKB1/TGFB1/IL1B/PDGFB/AP2A1/CEMIP	7
BP	GO:0034331	cell junction maintenance	7/7096	14/18670	0.2546	0.4927	0.3673	PLEKHA7/KIFC3/F2R/PKP2/CSF1R/PRTN3/NLGN2	7
BP	GO:0035358	regulation of peroxisome proliferator activated receptor signaling pathway	7/7096	14/18670	0.2546	0.4927	0.3673	STARD10/LEP/SIRT1/CITED2/ALOX15B/ASXL2/FABP5	7
BP	GO:0043144	snoRNA processing	7/7096	14/18670	0.2546	0.4927	0.3673	RNF113A/FBL/EXOSC2/EXOSC3/FBLL1/EXOSC6/EXOSC5	7
BP	GO:0043374	CD8-positive, alpha-beta T cell differentiation	7/7096	14/18670	0.2546	0.4927	0.3673	IRF1/CBFB/ZBTB7B/BCL2/GPR18/SOCS1/TNFSF8	7
BP	GO:0045198	establishment of epithelial cell apical/basal polarity	7/7096	14/18670	0.2546	0.4927	0.3673	WNT5A/OPHN1/SH3BP1/MSN/RHOA/FOXF1/LAMA1	7
BP	GO:0045346	regulation of MHC class II biosynthetic process	7/7096	14/18670	0.2546	0.4927	0.3673	SPI1/AZU1/JAK2/TLR4/SIRT1/HDAC2/IFNG	7
BP	GO:0046036	CTP metabolic process	7/7096	14/18670	0.2546	0.4927	0.3673	CTPS2/NME3/NME4/NME1/UCK1/CTPS1/UCKL1	7
BP	GO:0046133	pyrimidine ribonucleoside catabolic process	7/7096	14/18670	0.2546	0.4927	0.3673	UPP1/CDADC1/APOBEC3G/APOBEC3C/APOBEC2/APOBEC3B/CDA	7
BP	GO:0046629	gamma-delta T cell activation	7/7096	14/18670	0.2546	0.4927	0.3673	NOD2/EGR3/SOX13/PTPRC/LILRB1/GPR18/MICA	7
BP	GO:0046940	nucleoside monophosphate phosphorylation	7/7096	14/18670	0.2546	0.4927	0.3673	AK3/AK2/AK8/CMPK1/CMPK2/AK6/PNKP	7
BP	GO:0048308	organelle inheritance	7/7096	14/18670	0.2546	0.4927	0.3673	MAP2K1/STX5/PLK3/MAP2K2/MAPK1/VRK1/PDCD10	7
BP	GO:0048313	Golgi inheritance	7/7096	14/18670	0.2546	0.4927	0.3673	MAP2K1/STX5/PLK3/MAP2K2/MAPK1/VRK1/PDCD10	7
BP	GO:0051938	L-glutamate import	7/7096	14/18670	0.2546	0.4927	0.3673	PER2/SLC7A11/CLN8/ARL6IP1/PSEN1/ATP1A2/NTSR1	7
BP	GO:0060732	positive regulation of inositol phosphate biosynthetic process	7/7096	14/18670	0.2546	0.4927	0.3673	PTAFR/P2RY6/SNCA/CD244/ADCYAP1R1/P2RY1/NTSR1	7
BP	GO:0070669	response to interleukin-2	7/7096	14/18670	0.2546	0.4927	0.3673	IL2RG/PTPN2/PTK2B/IL2RB/STAT5A/SHC1/JAK1	7
BP	GO:0071361	cellular response to ethanol	7/7096	14/18670	0.2546	0.4927	0.3673	KCNMB1/SPI1/CCL7/ADCY7/CYBB/DNMT3A/PRKAA1	7
BP	GO:0071391	cellular response to estrogen stimulus	7/7096	14/18670	0.2546	0.4927	0.3673	CRHBP/SERPINB9/ARID5A/SRA1/TRIM24/BCAS3/MDM2	7
BP	GO:0071941	nitrogen cycle metabolic process	7/7096	14/18670	0.2546	0.4927	0.3673	ARG2/NAGS/CEBPA/SLC25A15/NMRAL1/SUOX/NR1H4	7
BP	GO:0090231	regulation of spindle checkpoint	7/7096	14/18670	0.2546	0.4927	0.3673	DUSP1/DYNC1LI1/CDK5RAP2/LCMT1/NDC80/GEN1/PCID2	7
BP	GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint	7/7096	14/18670	0.2546	0.4927	0.3673	DUSP1/DYNC1LI1/CDK5RAP2/LCMT1/NDC80/GEN1/PCID2	7
BP	GO:1901626	regulation of postsynaptic membrane organization	7/7096	14/18670	0.2546	0.4927	0.3673	SLC7A11/APOE/FZD9/CRIPT/SSH1/LRP4/ZMYND8	7
BP	GO:1903351	cellular response to dopamine	7/7096	14/18670	0.2546	0.4927	0.3673	ATF4/SIN3A/ABL1/LRRK2/HDAC2/DNM2/MAPK1	7
BP	GO:1903504	regulation of mitotic spindle checkpoint	7/7096	14/18670	0.2546	0.4927	0.3673	DUSP1/DYNC1LI1/CDK5RAP2/LCMT1/NDC80/GEN1/PCID2	7
BP	GO:2001212	regulation of vasculogenesis	7/7096	14/18670	0.2546	0.4927	0.3673	RAPGEF2/RAP1A/HEY1/HIF1AN/EMP2/HEY2/CD34	7
BP	GO:2001279	regulation of unsaturated fatty acid biosynthetic process	7/7096	14/18670	0.2546	0.4927	0.3673	ANXA1/PTGS2/CD74/IL1B/SIRT1/FABP5/ABCD1	7
BP	GO:0006304	DNA modification	48/7096	116/18670	0.2551	0.4933	0.3678	FOS/SPI1/ASCC3/ALKBH1/MYC/KDM1B/EZH2/TET2/NEIL2/UNG/MBD1/CDADC1/PIWIL4/MBD3/PARP2/USP9X/PPM1D/MTRR/MOV10L1/APOBEC3G/TDG/APOBEC3C/OTUD4/APOBEC2/KMT2E/FTO/DNMT3L/PARP3/CTCF/PRMT5/ZMPSTE24/BRCA1/DNMT3A/USP7/APOBEC3B/EXOSC3/RLF/PICK1/EXOSC6/ALKBH2/MGMT/MTA2/MBD4/WT1/GRHL2/TET1/EXOSC5/SMUG1	48
BP	GO:1900180	regulation of protein localization to nucleus	48/7096	116/18670	0.2551	0.4933	0.3678	FYN/PARP9/LMNA/NUP62/PTGS2/CHP1/FLNA/RAN/GSK3B/HCLS1/TGFB1/SIN3A/RAB23/CD36/LEP/RASSF5/PRKCD/LILRB4/HYAL2/KAT7/ZPR1/UBR5/MDFIC/MFHAS1/MAVS/FLCN/NOLC1/MCRS1/DTX3L/DCLK2/BMP4/CD2AP/CCT4/FBXO4/CCT8/TRIM29/PSEN1/MAPK1/IFNG/CLDN18/CHP2/PIN1/CARD10/PKIA/TERT/SMO/TARDBP/SESN2	48
BP	GO:0048545	response to steroid hormone	153/7096	385/18670	0.2556	0.4942	0.3684	FOS/VDR/TLR2/DUSP1/ANXA1/CDKN1A/PAQR7/NR4A2/ZFP36/TXNIP/FOSB/AIFM1/ATP1A1/SRD5A1/PTGER2/GPAM/THRA/PTGS2/NCOA4/SPP1/UBA5/PPARD/TFPI/DDRGK1/CREBRF/YWHAH/CBFB/JAK2/GSTP1/TNF/AKAP13/SKP2/AKR1C3/HNMT/RAN/IGFBP7/KRAS/AGL/ANXA3/RELA/TRIM68/UBE3A/ZBTB7A/TGFB1/ALAD/PTAFR/PAK1/NR3C2/NCOA3/PCK2/NR1H2/LATS1/CATSPER1/TFAP4/FLT3/RBBP7/CASP3/PMEPA1/GRIP1/AIF1/NR1D2/S100B/UBR5/BUD31/IDH1/IGFBP2/IL1RN/SIRT1/KLF9/BMP7/CCND1/RHOXF1/IL6/PDCD7/SMYD3/PPARGC1A/SPARC/CALCOCO1/SCGB1A1/PAM/BCL2L11/NCOR1/KAT5/RXRA/CCNE1/PFKFB1/BCL2/PCNA/BMP4/NEDD4/HMGB2/NR2E3/NR1H3/UFM1/TYMS/CTSV/PDX1/CYBA/CYBB/DDIT4/NPAS4/CALR/BRCA1/EGFR/TPH2/PPARA/CLOCK/FHL2/SLIT2/MAOB/ADAM9/MDM2/BAD/ZFP36L2/TGFB3/CPN1/RORA/CAD/FOSL1/EIF4E/ARNTL/NR4A3/TGFB1I1/STRN3/RNF4/DNAJA1/NR2F1/RB1/CARM1/ESRRB/NR2E1/DDX54/FOXP1/RHOA/ENG/PAQR8/ACR/NR2C2/ATP1A2/TADA3/ALDH3A1/ACTA1/NRIP1/DAXX/LBH/NR1H4/UCN3/MGARP/NR2F6/FOXO3/TAF7/FOXH1/SLIT3	153
BP	GO:0007052	mitotic spindle organization	44/7096	106/18670	0.2582	0.4991	0.3721	SUN2/STMN1/NUP62/RAB11A/FLNA/RAN/CHMP4B/PSRC1/KIF3B/MAP4/CENPE/PLK2/KIF4A/KIF2A/RCC1/ZNF207/SPICE1/BCCIP/NDC80/PARP3/CHMP2A/DCTN2/NUF2/CHMP1A/VPS4B/TUBG2/CLASP2/GPSM2/SMC3/SPC25/CDC20/STAG1/TBCE/VCP/MISP/RHOA/AURKA/KPNB1/EFHC1/MSTO1/CHMP1B/AAAS/PRC1/WRAP73	44
BP	GO:0051588	regulation of neurotransmitter transport	57/7096	139/18670	0.2587	0.4998	0.3726	APBA1/RAP1B/SYT11/RGS2/FLOT1/PER2/P2RX7/KCNC4/GSK3B/LILRB1/STXBP1/UNC13B/ARL6IP1/PNKD/FBXL20/CDK5/RAB3GAP1/DTNBP1/RAP1A/PREPL/LRRK2/ADCY1/TOR1A/P2RX1/ADORA2B/VPS18/NAPA/RAB5A/CAMK2A/CHRM2/DNM1L/CHRNA4/ATP2A2/MAOB/DVL1/PSEN1/FMR1/RAB3A/CHRNB2/P2RY4/SYT9/SYT1/RAB3B/SNX4/VAMP1/SYT4/SNCAIP/SNCA/KCNMB4/RIMS2/ATP1A2/WNT7A/P2RY1/TACR2/NTSR1/MEF2C/APLN	57
BP	GO:0006417	regulation of translation	168/7096	424/18670	0.2596	0.5006	0.3732	EIF1/PINK1/ZFP36/TSC1/STAT3/VIM/DPH3/PPP1R15A/GAPDH/ENC1/TOB1/ALKBH1/RPS6KA3/BANK1/RGS2/PER2/RNF139/AGO2/SEPSECS/TNF/EIF1B/KHDRBS1/YTHDF3/MOV10/HNRNPR/METTL14/GIGYF2/SECISBP2/BTG2/TRNAU1AP/ATF4/PAIP1/EIF6/CDK4/UQCC1/SARNP/PTAFR/HSPB1/PTK2B/EIF4E3/METTL3/MTIF2/SECISBP2L/CNBP/RBM4/SAMD4B/RBM4B/PIWIL4/EIF2B5/HABP4/NCK1/EIF4B/NPM1/DPH5/PURA/LARP4/RBM8A/GUF1/UQCC2/CCL5/DHX9/DAPK1/ZC3H12D/LSM14B/ACO1/PPP1R15B/EIF4E2/EIF4H/EIF2S1/EIF4EBP2/CAPRIN1/IL6/EIF4G2/CYFIP1/DNAJC1/ATXN2/NOLC1/NAT10/LSM14A/PUM2/DDX3X/ILF3/SERP1/RBM3/RPS9/MAPKAPK5/DPH2/SHMT2/KBTBD8/FTO/RXRA/USP16/TARBP2/XRN1/EIF4G3/CPEB1/PRR16/AGO1/ETF1/DDX1/ITGA2/EIF3B/TNRC6B/TYMS/EIF5/GRB7/ZCCHC4/TNRC6A/HNRNPD/CPEB3/YBX3/IREB2/POLR2D/CALR/IMPACT/UNK/COA3/SHMT1/PPP1CA/EIF2AK2/LARP4B/C1QBP/DHFR/CNOT7/EIF5A/NGRN/FMR1/MAPK1/KLHL25/NOTCH4/EIF2AK1/ZFP36L2/EIF4G1/EIF2B1/RPUSD3/EIF2A/MKNK2/EIF4E/RPS6KB2/JMJD4/CNOT10/MTRF1/EIF2AK4/MTOR/RHOA/APP/SAMD4A/ZNF706/SOX4/TRMT10C/MPV17L2/PUS7/DIO2/EIF2B2/ROCK2/DNAJC24/EIF4ENIF1/SYNCRIP/BOLL/SESN2/PA2G4/MIR205/PAIP2B/CPEB2/FOXO3/PLEKHN1/NEMF/UPF1	168
BP	GO:0097006	regulation of plasma lipoprotein particle levels	42/7096	101/18670	0.2597	0.5006	0.3732	CSK/NPC2/LIPA/APOC1/SCARB1/PLA2G7/SOAT1/PRKACB/HMOX1/CETP/APOE/HDLBP/CD36/LRPAP1/HNRNPK/ABCA1/LDLR/LMF1/EHD1/APOBR/DGAT2/ABCA5/APOA5/ARF1/LCAT/AP2A2/ABCG1/PRKACA/AP2S1/AP2A1/ABCA7/ANXA2P2/CES3/APOA1/NCEH1/AP2M1/ANXA2/MPO/NR1H4/CNPY2/ALB/LPCAT3	42
BP	GO:0006363	termination of RNA polymerase I transcription	14/7096	31/18670	0.2598	0.5006	0.3732	CCNH/POLR2L/TAF1B/POLR2H/GTF2H4/TAF1D/POLR1C/POLR2F/ZMPSTE24/POLR2K/ERCC2/TAF1C/TBP/CD3EAP	14
BP	GO:0009154	purine ribonucleotide catabolic process	14/7096	31/18670	0.2598	0.5006	0.3732	ACOT7/HDDC3/PDE4B/HINT1/NUDT9/MLYCD/NUDT3/PDE7A/NUDT7/PDE8A/AMPD3/ABCD1/NUDT16/PDE8B	14
BP	GO:0021988	olfactory lobe development	14/7096	31/18670	0.2598	0.5006	0.3732	SKI/WNT5A/ATF5/EXT1/SRF/LRRK2/ARX/ID2/SLIT2/NR2E1/CSF1R/EFNA2/AGTPBP1/KIF14	14
BP	GO:0045880	positive regulation of smoothened signaling pathway	14/7096	31/18670	0.2598	0.5006	0.3732	POR/CHSY1/DISP1/EVC/IFT172/PDCL/CTNNA1/INTU/TUBD1/GORAB/SHOX2/SMO/SCUBE3/GAS8	14
BP	GO:0046471	phosphatidylglycerol metabolic process	14/7096	31/18670	0.2598	0.5006	0.3732	SLC27A1/PLA2G12A/HADHB/CDS2/PTPMT1/LPGAT1/CRLS1/PLA2G3/HADHA/PLA2G6/SERAC1/TAZ/LPCAT1/PGS1	14
BP	GO:0048710	regulation of astrocyte differentiation	14/7096	31/18670	0.2598	0.5006	0.3732	MIR142/MBD1/BMP2/LDLR/IL6ST/TTBK1/IL6/ID2/CLCF1/DAB1/HES1/PRPF19/NR2E1/BIN1	14
BP	GO:0070306	lens fiber cell differentiation	14/7096	31/18670	0.2598	0.5006	0.3732	SKIL/VIM/SLC7A11/ZEB2/MAF/TGFB1/CDKN1C/TBC1D20/CDKN1B/TDRD7/KDM5B/PITX3/BFSP2/WNT7A	14
BP	GO:0000723	telomere maintenance	66/7096	162/18670	0.2604	0.5014	0.3738	MYC/HUS1B/ERCC4/MAP3K4/SMC5/SMC6/RPA1/PKIB/NAF1/HNRNPA1/SP100/PRIM2/HNRNPA2B1/POLD4/TEP1/NSMCE2/XRCC5/DCP2/PML/POLD2/NAT10/RFC3/PTGES3/ATM/TNKS1BP1/MAPKAPK5/NHP2/HNRNPC/CCNE1/XRN1/PCNA/XRCC1/PARP3/ERCC1/GAR1/HNRNPD/CCT4/FBXO4/DCLRE1A/CCT8/ATR/USP7/MAPK1/RTEL1/TELO2/ACD/EXO1/CTC1/POLD1/XRCC6/DCLRE1C/GNL3L/HSP90AB1/POLA1/POLA2/TERT/PRKCQ/POT1/POLE4/NOP10/GNL3/PNKP/FEN1/RECQL4/NEK7/UPF1	66
BP	GO:0015718	monocarboxylic acid transport	66/7096	162/18670	0.2604	0.5014	0.3738	SLC27A1/APBA1/ANXA1/PLA2G12A/SLC27A3/FABP4/AQP9/SLCO3A1/PPARD/MIF/SLC25A20/SLC38A7/PLIN2/P2RX7/APOE/SLCO2B1/CPT2/STARD10/ABCD3/CD36/LEP/ACSL4/AKR1C1/IL1B/SLC27A2/MPC2/ACACB/ATP8B1/TNFRSF11A/FABP3/IRS2/PNPLA8/SLC16A6/MFSD2A/PLA2G3/PRKAG2/NCOR1/NMUR2/RXRA/SLC16A2/SLC16A1/CPT1A/ABCB4/SLC10A1/SLC5A6/ABCB11/GOT2/SLC16A7/PPARA/NMB/SLC5A8/PLA2G6/ABCC3/ABCC4/CROT/SLC6A13/SLCO1C1/ABCD1/SLC6A12/SPX/THRSP/NR1H4/NTSR1/SLCO1B1/SLC16A5/STRA6	66
BP	GO:0031960	response to corticosteroid	66/7096	162/18670	0.2604	0.5014	0.3738	FOS/DUSP1/ANXA1/CDKN1A/ZFP36/FOSB/AIFM1/SRD5A1/PTGS2/CREBRF/GSTP1/TNF/AKAP13/AKR1C3/HNMT/IGFBP7/KRAS/AGL/ANXA3/TGFB1/ALAD/PTAFR/PCK2/TFAP4/FLT3/CASP3/AIF1/S100B/IGFBP2/IL1RN/KLF9/CCND1/IL6/PDCD7/SMYD3/SPARC/SCGB1A1/PAM/BCL2L11/PFKFB1/BCL2/PCNA/TYMS/CTSV/PDX1/CYBA/CYBB/DDIT4/NPAS4/EGFR/TPH2/SLIT2/MAOB/ADAM9/BAD/ZFP36L2/CPN1/CAD/FOSL1/EIF4E/RHOA/ENG/ALDH3A1/UCN3/FOXO3/SLIT3	66
BP	GO:0007006	mitochondrial membrane organization	55/7096	134/18670	0.2606	0.5016	0.3739	BMF/PINK1/CHCHD6/SLC35F6/BLOC1S2/STAT3/PMAIP1/YWHAH/SLC9A1/TMEM14A/GSK3B/ALKBH7/CLN8/APOO/MPV17L/FZD9/SFN/OMA1/CASP8/RHOT2/CHCHD10/AFG3L2/SLC25A5/PDCD5/BCL2L11/MAPK8/TMEM102/BCL2/BAX/TOMM22/GZMB/THEM4/OXA1L/YWHAQ/CAMK2A/TOMM20/TIMM22/MUL1/AGK/ACAA2/LETM1/HSPA4/YWHAE/BAD/PPP1R13B/NAIF1/MOAP1/CNP/YWHAG/TAZ/SNCA/TIMM50/BAK1/APOOL/TIMM9	55
BP	GO:0002449	lymphocyte mediated immunity	140/7096	352/18670	0.2624	0.5049	0.3764	MYO1G/CCR2/PTPN6/IL27RA/SERPINB9/STX7/BCL10/MAD2L2/CD55/IRF7/C1RL/SLC11A1/STAT6/BCL6/NLRP3/SMAD7/CD40/CD1C/CEBPG/FGL2/CTSC/IL4R/PTPRC/P2RX7/CD1E/HFE/LAMP1/BATF/TNF/CD74/LILRB1/IL7R/DENND1B/CD226/TGFB1/PPP3CB/IL18R1/POU2F2/UNG/PRDX1/LEP/SWAP70/PRKCD/FAM49B/HLA-F/CORO1A/TRAF6/ZBTB1/CLC/TCIRG1/IL20RB/HLA-E/HLA-B/RSAD2/IL1B/CLEC12B/FBXO38/AGER/RASGRP1/CD1B/PIK3R6/HMGB1/CRK/CLU/TRPM4/IL1R1/HLA-G/SERPING1/TRBC1/IL6/CR1/HLA-C/BTN3A2/CD96/EMP2/FCER2/MLH1/PARP3/ERCC1/GZMB/CLCF1/CCR6/UNC13D/BTN3A3/PVR/LAG3/CR2/CD1D/IL12RB1/CD1A/LGALS9/LIG4/C1R/FZD5/GZMM/ULBP2/CRTAM/C1QBP/VAV1/KIR2DL4/IL18/FADD/TRAF2/TFRC/PRF1/TNFSF4/AP1G1/TLR8/IL13RA2/EXO1/C1QC/HLA-A/HAVCR2/SCART1/NCR3/SERPINB4/EXOSC3/GAPT/IL12B/SH2D1A/SLA2/MICA/PRKCZ/TBX21/NCR1/IL18RAP/APLF/EXOSC6/MALT1/MASP2/CD8A/WAS/PAXIP1/ATAD5/RAB27A/IL23A/APCS/IGHD/C7/RFTN1	140
BP	GO:0009799	specification of symmetry	53/7096	129/18670	0.2625	0.5049	0.3764	DLL1/ACVR2B/WNT5A/DISP1/BBS5/AP1B1/SMAD2/LRRC6/SETDB2/IFT172/PKD2/IFT57/MIB1/KIF3B/HIF1A/MEGF8/ARL13B/SRF/DPCD/MICAL2/PSKH1/RFX3/MKKS/MESP1/IFT52/CITED2/BBS4/BMP4/DNAI2/DYNC2LI1/BBS7/PCSK5/MKS1/CCDC151/C9orf116/CFC1/PCSK6/PSEN1/DNAI1/ENG/IFT74/AIDA/FOXF1/NEK8/CER1/GJA1/GREM1/SMO/DAAM2/C2CD3/GAS8/MEF2C/FOXH1	53
BP	GO:0001578	microtubule bundle formation	38/7096	91/18670	0.2625	0.5049	0.3764	MAP1S/CHP1/LRRC6/PSRC1/CLIP1/SPAG1/CDK5RAP2/BBS2/TPPP3/DNAL1/CCSER2/ZNF207/PLA2G3/DNAI2/DNAAF2/RSPH9/TTLL3/CCDC151/CCDC65/CAPN6/PIH1D3/TTLL1/DNAI1/TPGS1/LRRC61/NCKAP5L/CCDC63/SPAG17/CCDC66/UBE2B/DNAH8/TTLL6/TPPP/RP1/AAAS/PRC1/GAS8/TRIM46	38
BP	GO:0010742	macrophage derived foam cell differentiation	16/7096	36/18670	0.2636	0.5064	0.3775	STAT1/SOAT1/NFKBIA/CETP/NFKB1/TGFB1/CD36/NR1H2/ABCA1/ABCA5/ALOX15B/ABCG1/NR1H3/IL18/PPARA/MAPK9	16
BP	GO:0045841	negative regulation of mitotic metaphase/anaphase transition	16/7096	36/18670	0.2636	0.5064	0.3775	DUSP1/MAD2L2/DYNC1LI1/SPDL1/KLHL22/CDK5RAP2/ZNF207/LCMT1/ATM/BUB3/NDC80/GEN1/ZW10/CDC20/PCID2/IK	16
BP	GO:0090077	foam cell differentiation	16/7096	36/18670	0.2636	0.5064	0.3775	STAT1/SOAT1/NFKBIA/CETP/NFKB1/TGFB1/CD36/NR1H2/ABCA1/ABCA5/ALOX15B/ABCG1/NR1H3/IL18/PPARA/MAPK9	16
BP	GO:0090218	positive regulation of lipid kinase activity	16/7096	36/18670	0.2636	0.5064	0.3775	FPR2/NOD2/LYN/FLT1/ATG14/TGFB1/PTK2B/FLT3/FGR/P2RY12/PDGFB/EPHA8/PTK2/EEF1A2/CCL19/CCR7	16
BP	GO:0003333	amino acid transmembrane transport	36/7096	86/18670	0.2639	0.5067	0.3777	SLC43A2/SLC38A6/SLC36A1/RGS2/SLC38A7/PER2/SLC7A11/CLN8/SLC7A7/ARL6IP1/SLC7A6/PRAF2/SLC7A5/SLC16A10/SLC1A4/SLC43A1/SLC25A15/LRRC8D/SLC38A1/SLC7A1/SLC25A12/SLC6A5/SLC7A8/SLC36A4/LRRC8A/SLC25A13/PSEN1/SLC7A2/SLC25A22/SLC25A38/SLC6A12/ATP1A2/LRRC8E/SLC38A5/SLC38A9/NTSR1	36
BP	GO:0014013	regulation of gliogenesis	51/7096	124/18670	0.2644	0.5075	0.3784	CCR2/CX3CR1/TLR2/LYN/SKI/DUSP10/RNF10/SLC45A3/CERS2/TNF/EZH2/TNFRSF21/MIR142/RELA/TGFB1/MBD1/ASCL2/BMP2/IL1B/LDLR/P2RY12/LRP1/CREB1/IL6ST/ZNF488/TTBK1/ETV5/IL6/IDH2/PLAG1/DICER1/HDAC2/ID2/CLCF1/SPINT1/DAB1/PITX3/PRMT5/HES1/PPP1CC/TREM2/PRPF19/TERT/NR2E1/MTOR/GPR183/DAG1/PTPRZ1/DAAM2/BIN1/MIR146A	51
BP	GO:0032204	regulation of telomere maintenance	34/7096	81/18670	0.2651	0.5085	0.3791	MYC/ERCC4/MAP3K4/PKIB/NAF1/HNRNPA1/HNRNPA2B1/XRCC5/DCP2/PML/NAT10/ATM/MAPKAPK5/HNRNPC/XRN1/XRCC1/ERCC1/HNRNPD/CCT4/FBXO4/CCT8/ATR/USP7/MAPK1/RTEL1/ACD/CTC1/GNL3L/PRKCQ/POT1/GNL3/PNKP/NEK7/UPF1	34
BP	GO:2001021	negative regulation of response to DNA damage stimulus	34/7096	81/18670	0.2651	0.5085	0.3791	TRIM32/CDKN2D/MAD2L2/MIF/ACKR3/CD44/KLHL15/CD74/ERCC4/MAGEF1/CXCL12/PTTG1IP/TMEM161A/RMI2/UBR5/SMCHD1/NUDT16L1/CLU/SIRT1/ELL3/MUC1/BCL2/XRCC1/ERCC1/THOC5/DYRK3/MDM2/RTEL1/TAF9B/SNAI1/TRIAP1/AUNIP/ATAD5/DDIAS	34
BP	GO:0051146	striated muscle cell differentiation	117/7096	293/18670	0.2656	0.5095	0.3798	IGF1/MYOF/SLC8A1/TRIM32/DLL1/MEF2A/SKI/RBPJ/LMNA/TSC1/CAPN2/RGS2/SIK1/FLOT1/UCHL1/KLHL41/IL4R/CXCL9/MORF4L2/EZH2/AKAP13/SLC9A1/CXCL10/KRAS/TMOD3/CD53/TGFB1/PAK1/CFL2/PLEKHO1/SRF/NRG1/CBY1/DYRK1B/FLT3LG/RYR1/BMP2/PARP2/ACTC1/VEGFA/CASP3/MYBPC3/EHD1/DMD/AFG3L2/HOMER1/CTDP1/G6PD/MESP1/SMYD3/NLN/MYH9/PDLIM5/PTGFRN/MYOG/PGM5/RXRA/CAPN9/BCL2/BMP4/TPM1/ADAM12/CYP26B1/NFATC2/HDAC4/YY1/KLF5/OBSCN/KLHL40/KRT8/MAMSTR/MMP14/KDM6B/ZMPSTE24/CALR/CACYBP/MYOZ1/LMOD3/ALPK3/PPARA/CAV3/BIN3/HEY2/MYOM2/WNT1/KAT2A/HAMP/SHOX2/DNER/IFT20/MAP2K4/CASQ1/CAPN3/CASQ2/PIN1/RB1/FZD7/SYNPO2L/MSX1/GPX1/CSRP1/MTOR/HDAC5/P2RX2/CHUK/MYH3/TMEM119/WNT10B/GREM1/ACTA1/CACNA1H/SMO/WT1/KEL/TNNT1/MEF2C/MYF6	117
BP	GO:0034122	negative regulation of toll-like receptor signaling pathway	18/7096	41/18670	0.2661	0.51	0.3803	LYN/GRAMD4/TNFAIP3/LY96/LGR4/LILRA2/IRAK3/TICAM1/TLR4/CACTIN/CD300LF/MFHAS1/OTUD4/CD300A/RAB7B/TLR3/TYRO3/TLR6	18
BP	GO:0061028	establishment of endothelial barrier	18/7096	41/18670	0.2661	0.51	0.3803	MYADM/EZR/S1PR3/RAP1B/F11R/TNF/RDX/RAPGEF2/RAP2C/VEGFA/IL1B/RAP1A/PPP1R16B/CDH5/MSN/ENG/WNT7A/ROCK2	18
BP	GO:0061351	neural precursor cell proliferation	60/7096	147/18670	0.2666	0.511	0.3809	CX3CR1/APPL2/LYN/WNT5A/FLNA/ATF5/SHCBP1/ZEB2/BTG2/PLXNB2/TGFB1/HIF1A/CTNNA1/PCM1/FZD9/VEGFA/PAFAH1B1/CTSZ/PSMG1/NUMB/ARHGEF2/ELL3/LRRK2/RPGRIP1/ASPM/ARX/DIXDC1/AKNA/DAGLB/DISC1/HOOK3/TARBP2/GNAI2/KDM2B/ID2/KCTD11/SPINT1/PITX3/DCT/WNT1/IFT20/RORA/EPHB1/NUMBL/TMEM14B/SOX5/ORC3/NR2E1/CEP120/RHOA/CX3CL1/PTPRZ1/FGF13/TRNP1/WNT7A/OTP/SMO/KIF14/FOXO3/ZNF335	60
BP	GO:0044786	cell cycle DNA replication	30/7096	71/18670	0.2671	0.5115	0.3814	BCL6/MCM6/FBXW7/GINS1/MCM2/GMNN/ZNF830/RPA1/DBF4B/PRIM2/POLD4/ZPR1/DONSON/POLD2/TIPIN/RFC3/PCNA/ZMPSTE24/MCM5/RTEL1/POLD1/SMC3/POLA1/POLA2/ORC3/POLE4/ATAD5/FEN1/E2F8/UPF1	30
BP	GO:0005978	glycogen biosynthetic process	20/7096	46/18670	0.2676	0.5115	0.3814	IGF1/PER2/GSK3B/AGL/DYRK2/PPP1R3E/INSR/GYS1/PPP1R3D/GYG2/IRS2/PHKG1/PGM2/INPP5K/PPP1R3B/PPP1R3F/PPP1CA/PPP1CB/ESRRB/MTOR	20
BP	GO:0009250	glucan biosynthetic process	20/7096	46/18670	0.2676	0.5115	0.3814	IGF1/PER2/GSK3B/AGL/DYRK2/PPP1R3E/INSR/GYS1/PPP1R3D/GYG2/IRS2/PHKG1/PGM2/INPP5K/PPP1R3B/PPP1R3F/PPP1CA/PPP1CB/ESRRB/MTOR	20
BP	GO:0043277	apoptotic cell clearance	20/7096	46/18670	0.2676	0.5115	0.3814	JMJD6/RHOBTB1/FCN1/MARCO/SCARB1/AXL/CD36/CD300LF/LRP1/HMGB1/TYROBP/XKR8/TGM2/NR1H3/ABCA7/MERTK/TREM2/MEGF10/TYRO3/RHOBTB2	20
BP	GO:0051646	mitochondrion localization	20/7096	46/18670	0.2676	0.5115	0.3814	MEF2A/MAP1S/UCHL1/HIF1A/TRAK2/RHOT2/MARK1/LRRK2/MARK2/SLC4A5/DNM1L/MUL1/KAT2A/KIF1B/TRAK1/ATCAY/MSTO1/UXT/MGARP/ALB	20
BP	GO:0071354	cellular response to interleukin-6	20/7096	46/18670	0.2676	0.5115	0.3814	SPI1/SOCS3/SBNO2/STAT3/PTPN2/STAT1/JAK2/NFKB1/RELA/CEBPA/IL6ST/IL6/PPARGC1A/SELPLG/FER/HAMP/PID1/ST18/JAK1/FGF23	20
BP	GO:0001701	in utero embryonic development	148/7096	373/18670	0.2676	0.5115	0.3814	IGF1/JUNB/EPAS1/KLF2/APBA1/SKIL/SOCS3/RBPJ/DAD1/TCTN1/CAPN2/ALKBH1/KEAP1/PSPH/CHTOP/MAP2K1/RDH10/GINS1/RNASEH2B/SMAD2/ALS2/SLC25A20/CCNB1IP1/CEBPB/SH3PXD2A/PKD2/CMIP/MIB1/CPT2/BPTF/SIN3A/HIF1A/VASH1/ZNF830/HEG1/PCGF2/SRF/LATS1/RBBP6/TFEB/TRAF6/MBNL1/STMN3/ZFP14/SYF2/MBD3/CEBPA/ASCL2/BMP2/VEGFA/CASP8/ZPR1/PSMC4/PALB2/WDR19/CDKN1C/CHST11/UBE2A/HEY1/NSUN2/EIF2S2/BMP7/EIF4E2/SLC39A1/LPAR6/OCRL/ACVR1B/PDGFB/C1orf43/PCDH12/WDR74/FLCN/BCOR/DNAJB6/MYH9/ARNT2/B9D1/PSMC3/RRP7A/BCL2L11/BMP5/RXRA/BMPR1A/TAB1/MAFG/TPM1/INPP5K/UBR3/SPINT1/NDEL1/PHF6/GRB2/YBX3/LIG4/KRT8/FZD5/HES1/ADA/NPAT/ARNT/PLCD1/UNK/COPS2/ANKRD11/EGFR/GINS4/HEY2/TMEM231/KAT2A/MAPK1/GNA13/RUNDC1/ZNF568/ERCC2/TGFB3/HNF1B/SNAI1/FOSL1/ATP7A/RPL7L1/NASP/FBLL1/PRPF19/MSX1/HS3ST6/POLB/ND4/HINFP/RTN4/FOXF1/PRMT1/ACTL6A/UBE2B/ENDOG/SPIC/CMTM3/GJA1/SMO/COPS3/PTCH1/C2CD3/GRHL2/HORMAD1/E2F8/TET1/NRK/TM4SF1/ZNF335	148
BP	GO:0015800	acidic amino acid transport	28/7096	66/18670	0.2678	0.5115	0.3814	APBA1/SLC38A7/PER2/P2RX7/SLC7A11/STXBP1/CLN8/UNC13B/ARL6IP1/PRAF2/RAB3GAP1/LRRC8D/SLC25A12/PPFIA4/GLS/LRRC8A/SLC25A13/PSEN1/RAB3A/PPFIA3/SYT1/SYT4/SNCA/SLC25A22/ATP1A2/LRRC8E/NTSR1/NTRK2	28
BP	GO:0051785	positive regulation of nuclear division	28/7096	66/18670	0.2678	0.5115	0.3814	IGF1/WNT5A/NUP62/RGCC/LRP5/TGFB1/SMC5/INSR/UBXN2B/IL1B/NSMCE2/NSFL1C/PHIP/PDGFB/ESPL1/ANAPC5/SPHK1/IL1A/NUSAP1/UBE2C/PLCB1/DLGAP5/ANAPC4/RB1/MSX1/AURKA/ANAPC11/UBE2B	28
BP	GO:0098656	anion transmembrane transport	115/7096	288/18670	0.2679	0.5115	0.3814	SLC43A2/SLC38A6/CLIC1/AQP9/SLC9A9/SLC36A1/SLC23A2/SLC25A19/SLC37A2/PCYOX1/RGS2/SLC25A20/SLC38A7/CLCN7/FOLR2/PER2/SLC37A4/SLC7A11/SLC9A1/SLC26A11/CPT2/CLN8/SLC7A7/ARL6IP1/XPR1/PTAFR/SLC7A6/PRAF2/SLC7A5/SLC16A10/GOPC/SLC1A4/CLCN3/CLCC1/ABCA1/SLC12A9/SLC25A10/SLC35B4/MPC2/ACACB/TTYH2/SLC35D1/SLC43A1/SLC25A15/LRRC8D/IRS2/SLC9A8/APOL1/CLIC4/SLC38A1/SLC9A7/SLC7A1/SLC12A2/SLC25A12/SLC26A8/PRKAG2/SLC12A8/SLC6A5/SLC7A8/FXYD1/CLIC6/SLC16A1/SLC46A1/CPT1A/SLC5A6/VDAC2/SLC4A5/SLC35B1/SLC35A3/SLC20A1/VDAC1/SLC26A4/SLC16A7/SLC36A4/LRRC8A/SLC25A13/SLC5A8/SLC20A2/PSEN1/CLCN4/SLC4A7/SLC4A1/SLC24A4/TTYH3/SLC7A2/CLCA1/SLC12A1/SLC12A7/VDAC3/MTOR/GABRA4/SLC25A22/SLC25A32/SLC24A2/SLC25A38/SLC12A4/SLC26A10/FXYD3/SLC35A2/SLC6A12/CLCN5/ATP1A2/LRRC8E/SLC38A5/SLC4A11/SLC9C2/THRSP/SLC35D2/GABRP/SLC4A3/SLC38A9/NTSR1/SLC12A6/BSND/STRA6	115
BP	GO:0006690	icosanoid metabolic process	47/7096	114/18670	0.2682	0.5115	0.3814	ALOX5/TLR2/ANXA1/ALOX5AP/PTGS2/MIF/PTGR1/MGST2/MGLL/CD74/AKR1C3/PLAA/ZADH2/PTGR2/CYP1B1/HPGD/CYP2J2/CYP2S1/IL1B/ACOX1/CES2/GSTA1/SIRT1/GPX4/PNPLA8/PTGES3/ALOX15B/DAGLB/PLA2G3/CYP2D6/CYP1A2/MAPKAPK2/HPGDS/FABP5/GGT7/MGST3/GGTA1P/GGT5/GPX1/ATP6V1B1/CYP4F3/ABHD16A/GGTLC1/CYP2A6/CYP2C8/PTGS1/CYP2U1	47
BP	GO:0030834	regulation of actin filament depolymerization	22/7096	51/18670	0.2683	0.5115	0.3814	TMOD3/LIMA1/TWF2/RDX/CFL2/CAPZA2/SWAP70/CAPG/CAPZA1/SH3BP1/SPTBN1/AVIL/CFL1/TRIOBP/ADD3/PLEK/SEMA5A/DMTN/LMOD3/SCIN/SPTA1/SPTBN2	22
BP	GO:0048260	positive regulation of receptor-mediated endocytosis	22/7096	51/18670	0.2683	0.5115	0.3814	HFE/TBC1D5/ARRB1/CD63/HNRNPK/VEGFA/PLCG2/SFRP4/CLU/APOA5/BICD1/DNM2/SERPINE1/AP2A1/ANXA2P2/FMR1/ANXA2/PICK1/CCL19/ATAD1/GREM1/APLN	22
BP	GO:0003170	heart valve development	26/7096	61/18670	0.2683	0.5115	0.3814	NOTCH2/RBPJ/DCHS1/TGFB1/BMP2/HEY1/BMPR1A/BMP4/NFATC1/OLFM1/FGFRL1/HEY2/SLIT2/MDM2/SHOX2/SNAI1/RB1/MTOR/ZBTB14/SOX4/ROCK2/ADAMTS9/MEF2C/BMPR2/SLIT3/STRA6	26
BP	GO:0006879	cellular iron ion homeostasis	26/7096	61/18670	0.2683	0.5115	0.3814	SLC40A1/SLC11A1/SOD1/ATP6AP1/NCOA4/CUL1/MYC/HFE/HMOX1/FBXL5/CYBRD1/HIF1A/FTL/ISCU/ABCB6/TTC7A/ATP6V1A/ACO1/SRI/GLRX3/CAND1/SLC46A1/IREB2/TFRC/HAMP/ABCB7	26
BP	GO:0042733	embryonic digit morphogenesis	26/7096	61/18670	0.2683	0.5115	0.3814	WNT5A/ECE1/IMPAD1/TULP3/ROR2/INTU/CHST11/IFT52/B9D1/HDAC2/BCL2L11/BMPR1A/BMP4/BAX/WDPCP/MKS1/TMEM231/MSX1/TRAF3IP1/TMEM107/ZBTB16/LRP4/WNT7A/GJA1/C2CD3/GRHL2	26
BP	GO:0001832	blastocyst growth	9/7096	19/18670	0.2692	0.5115	0.3814	IGF1/GINS1/ZNF830/ZPR1/PALB2/NDEL1/COPS2/GINS4/PRPF19	9
BP	GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin	9/7096	19/18670	0.2692	0.5115	0.3814	CTSZ/ATP6AP2/CPA3/PCSK5/F2R/CMA1/SUCNR1/CTSG/REN	9
BP	GO:0006448	regulation of translational elongation	9/7096	19/18670	0.2692	0.5115	0.3814	DPH3/ALKBH1/DPH5/DPH2/USP16/CPEB3/EIF5A/DNAJC24/CPEB2	9
BP	GO:0016082	synaptic vesicle priming	9/7096	19/18670	0.2692	0.5115	0.3814	STXBP1/UNC13B/SYNJ1/NAPA/RAB3A/VAMP1/SNAP29/CADPS2/SNCA	9
BP	GO:0021533	cell differentiation in hindbrain	9/7096	19/18670	0.2692	0.5115	0.3814	LDB1/OPHN1/CBLN1/RORA/FAIM2/ATP7A/KNDC1/WNT7A/AGTPBP1	9
BP	GO:0034471	ncRNA 5'-end processing	9/7096	19/18670	0.2692	0.5115	0.3814	RPP38/RPP25/ABT1/RPP14/HSD17B10/SSB/RPP40/POP7/TRMT10C	9
BP	GO:0035269	protein O-linked mannosylation	9/7096	19/18670	0.2692	0.5115	0.3814	TMTC3/POMGNT2/FKRP/SDF2L1/DPM1/TMTC2/POMT1/POMT2/DPM3	9
BP	GO:0046597	negative regulation of viral entry into host cell	9/7096	19/18670	0.2692	0.5115	0.3814	FCN1/IFITM2/IFITM1/IFITM3/PTX3/TRIM26/TRIM11/MID2/APCS	9
BP	GO:0046653	tetrahydrofolate metabolic process	9/7096	19/18670	0.2692	0.5115	0.3814	GCH1/MTHFD2/SHMT2/ATIC/TYMS/SHMT1/DHFR/ALDH1L1/PIPOX	9
BP	GO:0051131	chaperone-mediated protein complex assembly	9/7096	19/18670	0.2692	0.5115	0.3814	BBS10/BBS12/CLU/MKKS/PTGES3/STUB1/HSPA4/HSP90AB1/APCS	9
BP	GO:0051546	keratinocyte migration	9/7096	19/18670	0.2692	0.5115	0.3814	ARF6/PPARD/IQSEC1/MAPRE2/MMP9/ADAM9/HBEGF/MAP4K4/MTOR	9
BP	GO:0060716	labyrinthine layer blood vessel development	9/7096	19/18670	0.2692	0.5115	0.3814	JUNB/RBPJ/VASH1/HEY1/FZD5/HES1/PLCD1/HEY2/MAPK1	9
BP	GO:1990182	exosomal secretion	9/7096	19/18670	0.2692	0.5115	0.3814	STAM/RAB11A/SDCBP/CHMP2A/TSG101/HGS/VPS4B/IFNG/RAB27A	9
BP	GO:0030198	extracellular matrix organization	146/7096	368/18670	0.2698	0.5124	0.382	ITGAM/FN1/ICAM2/ADAMTSL4/COL23A1/VCAN/ICAM3/ITGA5/ITGB7/CAPN2/ITGB5/SPP1/TIMP2/CTSS/LAMB2/FLOT1/CD44/ADAM19/F11R/RGCC/CTSK/A2M/ADAM8/TNF/SH3PXD2A/MPV17/CST3/DPP4/KIF9/ITGAD/TGFB1/CYP1B1/COL8A2/LAMC3/ITGAL/COL4A2/ADAM15/NFKB2/PTX3/ITGA4/LOXL2/CSGALNACT1/ITGA7/LAMB3/QSOX1/CRISPLD2/ABL1/ITGA11/FURIN/MMP12/CAPNS2/LRP1/TPSAB1/IL6/PDGFB/PLOD1/ITGAE/DNAJB6/SULF2/SPARC/PTK2/ICAM4/ETS1/KLK4/LCP1/MMP9/ADAMTS2/SERPINE1/ADAM12/CD47/COL7A1/TIMP1/MMP3/PLOD2/MADCAM1/SPINT1/VIPAS39/ITGA2/HTRA1/CTRB2/SPOCK2/CTSV/MMP1/PDGFA/BCAN/VWF/ITGA3/MMP14/POMT1/CLASP2/COL2A1/JAM3/ANXA2P2/CMA1/ATXN1L/FSCN1/LAMA2/EFEMP2/ERCC2/COL4A3/TNXB/ITGA8/COL15A1/ATP7A/COL6A3/TMEM38B/RB1/DSPP/CTSG/THSD4/FOXF2/NID1/MMP2/NR2E1/COL18A1/COL11A2/SERAC1/TGFBI/ANXA2/HPN/MMP27/APP/MMP10/DAG1/IBSP/B4GALT1/MFAP2/ENG/HAPLN1/MMP16/FOXF1/GREM1/P4HA1/MMP19/AEBP1/WT1/ADAMTS4/SERPINF2/TLL2/SCUBE3/CAPNS1/PRSS2/HSD17B12/ADAMTS9/KAZALD1/LAMA1	146
BP	GO:0046928	regulation of neurotransmitter secretion	43/7096	104/18670	0.2719	0.5164	0.385	APBA1/RAP1B/SYT11/KCNC4/GSK3B/STXBP1/UNC13B/PNKD/FBXL20/CDK5/RAB3GAP1/DTNBP1/RAP1A/PREPL/LRRK2/ADCY1/P2RX1/ADORA2B/VPS18/NAPA/RAB5A/CAMK2A/CHRM2/DNM1L/CHRNA4/ATP2A2/DVL1/FMR1/RAB3A/CHRNB2/P2RY4/SYT9/SYT1/VAMP1/SYT4/SNCAIP/SNCA/KCNMB4/RIMS2/WNT7A/P2RY1/TACR2/MEF2C	43
BP	GO:0003158	endothelium development	54/7096	132/18670	0.2731	0.5183	0.3864	MYADM/SLC40A1/EZR/DLL1/COL23A1/ACVR2B/RBPJ/S1PR3/RAP1B/S1PR1/STARD13/F11R/TNF/CXCL10/RDX/RAPGEF2/HEG1/RAP2C/NRG1/VEGFA/IL1B/RAP1A/CSNK2B/HEY1/PPP1R16B/ADAMTS12/CDH5/GSTM3/MESP1/FGF1/MIR34A/BTG1/NRP1/PRKD2/BMP4/VEZF1/KDM6B/HEY2/ANXA2P2/NOTCH4/MSN/CD34/EDF1/COL18A1/GPX1/ANXA2/FOXP1/RHOA/ENG/MET/WNT7A/ROCK2/GJA1/BMPR2	54
BP	GO:0048762	mesenchymal cell differentiation	88/7096	219/18670	0.2741	0.5202	0.3878	HTR2B/FN1/GLIPR2/MAD2L2/RBPJ/PPP2CA/WNT5A/SEMA4B/SMAD7/KLHL12/ADIPOR1/KITLG/RDH10/STAT1/SMAD2/RGCC/EZH2/GSK3B/ZEB2/PBLD/LDLRAD4/TGFB1/HGF/HIF1A/ADAM15/HNRNPAB/NRG1/SEMA4A/LOXL2/FUZ/BMP2/IL1B/SEMA4C/SDCBP/S100A4/SEMA4D/HEY1/EFNB1/BMP7/IL6/ELL3/BCL9L/NOLC1/SEMA6B/AKNA/HDAC2/KBTBD8/BMP5/BMPR1A/NRP1/SEMA3B/ANXA6/STRAP/BCL2/ZNF703/BMP4/NRP2/CFL1/OLFM1/PEF1/SEMA5A/HES1/SPRY1/CORO1C/CLASP2/HEY2/SEMA5B/MAPK1/TGFB3/SNAI1/TGFB1I1/RET/GCNT2/PHACTR4/MSX1/FOXF2/FBXL17/MTOR/HPN/RTN4/DAG1/ENG/PDCD4/WNT10A/SDHAF2/GREM1/SMO/MEF2C	88
BP	GO:0002092	positive regulation of receptor internalization	11/7096	24/18670	0.2776	0.5254	0.3917	TBC1D5/ARRB1/CD63/VEGFA/PLCG2/SFRP4/FMR1/PICK1/ATAD1/GREM1/APLN	11
BP	GO:0007097	nuclear migration	11/7096	24/18670	0.2776	0.5254	0.3917	SUN2/FHOD1/PCM1/PAFAH1B1/CLMN/PTK2/SYNE2/HOOK3/TMEM201/CEP120/TRIM58	11
BP	GO:0009309	amine biosynthetic process	11/7096	24/18670	0.2776	0.5254	0.3917	SMS/OAZ2/SAT1/OAZ3/ODC1/AZIN1/TPH2/SRM/DBH/AZIN2/AGMAT	11
BP	GO:0042104	positive regulation of activated T cell proliferation	11/7096	24/18670	0.2776	0.5254	0.3917	IGF1/AGER/ICOSLG/HMGB1/IGFBP2/IL12RB1/IL18/FADD/IL12B/CD24/IL23A	11
BP	GO:0060396	growth hormone receptor signaling pathway	11/7096	24/18670	0.2776	0.5254	0.3917	LYN/STAT6/STAT3/JAK2/STAT5A/MBD5/PTK2/PXN/GHR/SOCS2/GHRL	11
BP	GO:0086064	cell communication by electrical coupling involved in cardiac conduction	11/7096	24/18670	0.2776	0.5254	0.3917	SLC8A1/ATP1A1/ATP1B2/SRI/ATP1B1/PRKACA/CAMK2D/HRC/PKP2/ATP1A2/GJA1	11
BP	GO:1902914	regulation of protein polyubiquitination	11/7096	24/18670	0.2776	0.5254	0.3917	NOD2/BIRC2/SKP2/PLAA/NMI/PTPN22/UBR5/FBXO4/FOXF2/XIAP/SASH1	11
BP	GO:1903020	positive regulation of glycoprotein metabolic process	11/7096	24/18670	0.2776	0.5254	0.3917	IGF1/CHP1/IL15/SOAT1/ARFGEF1/POMT1/PLCB1/POMT2/TCF7L2/CCL19/CCR7	11
BP	GO:2000209	regulation of anoikis	11/7096	24/18670	0.2776	0.5254	0.3917	PDK4/ITGA5/SIK1/ZNF304/TLE1/MCL1/PTK2/MYBBP1A/BCL2/NTRK2/BRMS1	11
BP	GO:0006368	transcription elongation from RNA polymerase II promoter	35/7096	84/18670	0.2791	0.5258	0.392	ELL2/ENY2/EZH2/PAF1/ELP4/CCNH/ADRM1/GTF2F2/POLR2L/CTDP1/AFF4/ELL3/CDK9/POLR2H/GTF2H4/EAF1/ELP3/CCNK/SUPT4H1/SSRP1/ZMYND11/GTF2F1/PBRM1/POLR2F/POLR2D/LEO1/POLR2K/ELP2/ERCC2/NELFCD/PCID2/SUPT16H/CCNT1/CDC73/POLR2I	35
BP	GO:0001837	epithelial to mesenchymal transition	57/7096	140/18670	0.2812	0.5258	0.392	GLIPR2/MAD2L2/RBPJ/PPP2CA/WNT5A/SMAD7/KLHL12/ADIPOR1/SMAD2/RGCC/EZH2/GSK3B/PBLD/LDLRAD4/TGFB1/HGF/HIF1A/ADAM15/HNRNPAB/LOXL2/FUZ/BMP2/IL1B/SDCBP/S100A4/HEY1/BMP7/IL6/ELL3/BCL9L/NOLC1/AKNA/HDAC2/KBTBD8/BMP5/STRAP/ZNF703/BMP4/OLFM1/PEF1/SPRY1/CLASP2/HEY2/TGFB3/SNAI1/TGFB1I1/GCNT2/MSX1/FOXF2/MTOR/HPN/RTN4/DAG1/ENG/PDCD4/SDHAF2/GREM1	57
BP	GO:0099173	postsynapse organization	66/7096	163/18670	0.2813	0.5258	0.392	FYN/LILRB2/SIPA1L1/ARF6/DNM3/WNT5A/POTEKP/LGMN/ABHD17C/SLC7A11/DOCK10/EPHB2/IL1RAP/APOE/ACTR2/ACTB/LRP8/UBE3A/ARF4/INSR/ACTN1/BAIAP2/FZD9/IGF1R/CDK5/ARHGAP22/PAFAH1B1/OPHN1/HOMER1/NDRG1/CAPRIN1/ETV5/KALRN/LRRK2/ARC/ARF1/PDLIM5/NRP1/NRP2/NTNG2/CFL1/SYNGAP1/MTMR2/SHANK1/ITGA3/BHLHB9/DNM1L/CRIPT/DVL1/CBLN1/EPHB1/INA/SPTBN2/IL1RAPL1/RELN/PICK1/SSH1/RER1/LRP4/WNT7A/CNKSR2/NLGN2/SHANK3/GHRL/ZMYND8/CAMK2B	66
BP	GO:0034764	positive regulation of transmembrane transport	82/7096	204/18670	0.2814	0.5258	0.392	IGF1/CCR2/KCNMB1/MEF2A/PINK1/CHP1/FLNA/CTSS/ACTN4/CXCL9/CXCL11/P2RX7/C2CD5/EPHB2/SLC9A1/CXCL10/TESC/PKD2/KCNE3/KCNIP2/ARL6IP1/PTAFR/INSR/P2RY6/ABL1/STIM2/GSTO1/PLCG2/RAP1A/DMD/CHCHD10/CREBL2/ATP1B2/IRS2/G6PD/ITLN1/ARC/SUMO1/CLTCL1/SRI/ATP1B3/ARF1/LRRC52/FXYD1/DNM2/BAX/ATP1B1/RHOQ/ADRB2/RNASEL/KCNQ1/AZIN1/F2R/NFE2L2/CEMIP/AMIGO1/ADIPOR2/STAC2/PSEN1/CASQ1/TREM2/CAPN3/IFNG/NR4A3/KIF5B/BDKRB1/EHD3/LACRT/CACNB3/TERT/RELN/SNCA/CX3CL1/CLIP3/AZIN2/KCNE2/APPL1/KLF15/SHANK3/HTR3A/NTSR1/WNK2	82
BP	GO:0002065	columnar/cuboidal epithelial cell differentiation	46/7096	112/18670	0.2819	0.5258	0.392	DLL1/CDKN1A/RBPJ/WNT5A/SOD1/CEBPB/GSK3B/HIF1A/BMP2/ABL1/PAFAH1B1/PTK6/RFX3/SAV1/B9D1/BMP5/RXRA/BCCIP/BMP4/WDPCP/SERPINE1/DLX3/TRIOBP/KLF5/TYMS/PDX1/HES1/CLOCK/HEY2/TMEM231/SLC4A7/BAD/WDR77/YIPF6/POU4F3/ARNTL/DSPP/MEN1/LRTOMT/C1GALT1/SOX4/SIDT2/TMC1/MCOLN3/SMO/MYCL	46
BP	GO:0005977	glycogen metabolic process	31/7096	74/18670	0.2824	0.5258	0.392	IGF1/PER2/GSK3B/AGL/DYRK2/PPP1R3E/INSR/GYS1/PPP1R3D/GYG2/PPP1R2/PHKB/IL6ST/IRS2/PCDH12/PHKG1/PGM2/PRKAG2/KHK/INPP5K/PPP1R3B/PPP1R3F/PPP1CC/PPP1CA/GAA/PYGM/PPP1CB/PYGL/ESRRB/MTOR/G6PC	31
BP	GO:0014015	positive regulation of gliogenesis	31/7096	74/18670	0.2824	0.5258	0.392	CCR2/TLR2/LYN/TNF/MIR142/RELA/TGFB1/BMP2/IL1B/P2RY12/LRP1/IL6ST/ZNF488/TTBK1/ETV5/IL6/PLAG1/DICER1/HDAC2/ID2/CLCF1/SPINT1/PRMT5/HES1/PPP1CC/TREM2/PRPF19/MTOR/DAG1/PTPRZ1/BIN1	31
BP	GO:0070373	negative regulation of ERK1 and ERK2 cascade	31/7096	74/18670	0.2824	0.5258	0.392	KLF4/EZR/DUSP1/DUSP6/LYN/CSK/GBP1/PTPN2/DUSP10/NLRP12/GSTP1/PTPRC/EPHB2/DUSP3/NDRG2/ARRB1/RANBP9/TLR4/ABL1/FLCN/DUSP4/TNIP1/RGS14/CHRNA10/BTN2A2/SPRY1/SPRED1/SPRY2/PIN1/ITGB1BP1/WNK2	31
BP	GO:0000303	response to superoxide	13/7096	29/18670	0.2826	0.5258	0.392	NQO1/GCH1/SOD1/TNF/ERCC6/CD36/PRDX1/ADPRHL2/BMP7/NFE2L2/DHFR/ATP7A/MPO	13
BP	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling	13/7096	29/18670	0.2826	0.5258	0.392	SLC8A1/SLC9A1/GSTO1/DMD/HDAC4/ATP1B1/PRKACA/CAMK2D/ATP2A2/CASQ2/HRC/TMEM38B/ATP1A2	13
BP	GO:0021602	cranial nerve morphogenesis	13/7096	29/18670	0.2826	0.5258	0.392	EPHB2/ADARB1/ATP8B1/TIFAB/EGR2/NRP1/NRP2/KCNA2/HOXB1/CHRNB2/EPHB1/PLXNA3/HOXA3	13
BP	GO:0021884	forebrain neuron development	13/7096	29/18670	0.2826	0.5258	0.392	WNT5A/ATF5/RAPGEF2/ARX/DCLK2/NRP1/DISC1/NRP2/UQCRQ/SLIT2/PLXNA3/ATP7A/LHX6	13
BP	GO:0031063	regulation of histone deacetylation	13/7096	29/18670	0.2826	0.5258	0.392	PINK1/SKI/BCL6/TGFB1/ZBTB7B/VEGFA/LRRK2/AKAP8/MAPK8/PRKD2/CAMK2D/JDP2/TADA3	13
BP	GO:0032232	negative regulation of actin filament bundle assembly	13/7096	29/18670	0.2826	0.5258	0.392	STMN1/ARAP1/S1PR1/PFN1/ARHGAP6/INPP5K/SHANK1/CLASP2/TACSTD2/TMEFF2/MET/WAS/SHANK3	13
BP	GO:0034367	protein-containing complex remodeling	13/7096	29/18670	0.2826	0.5258	0.392	APOC1/SCARB1/PLA2G7/CETP/APOE/GTF2E1/ABCA5/APOA5/LCAT/ABCG1/APOA1/MPO/ALB	13
BP	GO:0070723	response to cholesterol	13/7096	29/18670	0.2826	0.5258	0.392	SMAD2/LRP8/TGFB1/AACS/HMGCS1/ABCA1/CCR5/MLC1/INHBA/NFE2L1/DAG1/SMO/PTCH1	13
BP	GO:0090162	establishment of epithelial cell polarity	13/7096	29/18670	0.2826	0.5258	0.392	MPP5/ARF6/WNT5A/CYTH1/OPHN1/SH3BP1/SIPA1L3/HES1/MSN/FRMD4A/RHOA/FOXF1/LAMA1	13
BP	GO:1990126	retrograde transport, endosome to plasma membrane	13/7096	29/18670	0.2826	0.5258	0.392	RAB11A/ANKRD50/GRIPAP1/MICALL1/GRIP1/ANKRD27/RAB8A/SNX27/CCDC93/GRASP/LRRC7/VPS29/SNX17	13
BP	GO:2000036	regulation of stem cell population maintenance	13/7096	29/18670	0.2826	0.5258	0.392	ZNF322/NCOA3/LOXL2/PAX8/SAV1/BMP7/TAL1/KDM2B/HNF1B/ESRRB/ZNF706/SMO/LBH	13
BP	GO:0001682	tRNA 5'-leader removal	6/7096	12/18670	0.2834	0.5258	0.392	RPP38/RPP25/RPP14/SSB/RPP40/POP7	6
BP	GO:0002002	regulation of angiotensin levels in blood	6/7096	12/18670	0.2834	0.5258	0.392	CTSZ/ATP6AP2/CPA3/CMA1/CTSG/REN	6
BP	GO:0002003	angiotensin maturation	6/7096	12/18670	0.2834	0.5258	0.392	CTSZ/ATP6AP2/CPA3/CMA1/CTSG/REN	6
BP	GO:0002468	dendritic cell antigen processing and presentation	6/7096	12/18670	0.2834	0.5258	0.392	NOD2/SLC11A1/FGL2/CD74/CCL19/CCR7	6
BP	GO:0002551	mast cell chemotaxis	6/7096	12/18670	0.2834	0.5258	0.392	RAC2/VEGFB/SWAP70/VEGFA/RAC1/PIK3CD	6
BP	GO:0006020	inositol metabolic process	6/7096	12/18670	0.2834	0.5258	0.392	SLC5A3/IMPAD1/PPIP5K2/IMPA2/IPPK/IMPA1	6
BP	GO:0006216	cytidine catabolic process	6/7096	12/18670	0.2834	0.5258	0.392	CDADC1/APOBEC3G/APOBEC3C/APOBEC2/APOBEC3B/CDA	6
BP	GO:0006465	signal peptide processing	6/7096	12/18670	0.2834	0.5258	0.392	FURIN/IMMP2L/PCSK5/SPCS2/CLN5/SEC11A	6
BP	GO:0006563	L-serine metabolic process	6/7096	12/18670	0.2834	0.5258	0.392	PSPH/SHMT2/SERINC3/SHMT1/SRR/PHGDH	6
BP	GO:0006568	tryptophan metabolic process	6/7096	12/18670	0.2834	0.5258	0.392	IDO1/KYNU/HAAO/IDO2/ATP7A/TDO2	6
BP	GO:0006662	glycerol ether metabolic process	6/7096	12/18670	0.2834	0.5258	0.392	TMEM86A/AGPS/TMEM86B/FAR1/TXN/GNPAT	6
BP	GO:0009972	cytidine deamination	6/7096	12/18670	0.2834	0.5258	0.392	CDADC1/APOBEC3G/APOBEC3C/APOBEC2/APOBEC3B/CDA	6
BP	GO:0014831	gastro-intestinal system smooth muscle contraction	6/7096	12/18670	0.2834	0.5258	0.392	HTR2B/PTAFR/SULF2/SPX/TACR2/GHRL	6
BP	GO:0014889	muscle atrophy	6/7096	12/18670	0.2834	0.5258	0.392	IL15/GATM/PPARGC1A/MYOG/MTOR/FOXO3	6
BP	GO:0015697	quaternary ammonium group transport	6/7096	12/18670	0.2834	0.5258	0.392	SLC22A4/SLC25A20/SLC22A5/SLC25A47/SLC25A45/SLC22A16	6
BP	GO:0016045	detection of bacterium	6/7096	12/18670	0.2834	0.5258	0.392	NOD2/TLR1/TLR2/CD1D/PGLYRP4/TLR6	6
BP	GO:0019336	phenol-containing compound catabolic process	6/7096	12/18670	0.2834	0.5258	0.392	FAH/MAOA/MAOB/DBH/LRTOMT/DIO2	6
BP	GO:0021819	layer formation in cerebral cortex	6/7096	12/18670	0.2834	0.5258	0.392	MBOAT7/CDK5/PAFAH1B1/CDK5R2/NR2E1/RELN	6
BP	GO:0031126	snoRNA 3'-end processing	6/7096	12/18670	0.2834	0.5258	0.392	FBL/EXOSC2/EXOSC3/FBLL1/EXOSC6/EXOSC5	6
BP	GO:0031392	regulation of prostaglandin biosynthetic process	6/7096	12/18670	0.2834	0.5258	0.392	ANXA1/PTGS2/CD74/IL1B/SIRT1/FABP5	6
BP	GO:0032905	transforming growth factor beta1 production	6/7096	12/18670	0.2834	0.5258	0.392	FURIN/ATP6AP2/TYROBP/CD2AP/LAPTM4B/CX3CL1	6
BP	GO:0033197	response to vitamin E	6/7096	12/18670	0.2834	0.5258	0.392	HMGCS1/ALAD/LEP/CAT/CCND1/ADA	6
BP	GO:0034497	protein localization to phagophore assembly site	6/7096	12/18670	0.2834	0.5258	0.392	ATG13/WIPI1/ATG9A/PACS2/WDR45B/TRAPPC8	6
BP	GO:0035751	regulation of lysosomal lumen pH	6/7096	12/18670	0.2834	0.5258	0.392	GRN/CLN3/VPS33A/LRRK2/CLN6/CLN5	6
BP	GO:0045416	positive regulation of interleukin-8 biosynthetic process	6/7096	12/18670	0.2834	0.5258	0.392	CLEC7A/BCL10/TNF/CD74/TLR4/TLR8	6
BP	GO:0045955	negative regulation of calcium ion-dependent exocytosis	6/7096	12/18670	0.2834	0.5258	0.392	RAP1B/RAP1A/GNAI2/FMR1/STXBP3/SYT4	6
BP	GO:0046087	cytidine metabolic process	6/7096	12/18670	0.2834	0.5258	0.392	CDADC1/APOBEC3G/APOBEC3C/APOBEC2/APOBEC3B/CDA	6
BP	GO:0046929	negative regulation of neurotransmitter secretion	6/7096	12/18670	0.2834	0.5258	0.392	RAP1B/SYT11/PNKD/RAP1A/FMR1/SYT4	6
BP	GO:0048642	negative regulation of skeletal muscle tissue development	6/7096	12/18670	0.2834	0.5258	0.392	TGFB1/S100B/YBX3/EPHB1/USP19/TLL2	6
BP	GO:0051095	regulation of helicase activity	6/7096	12/18670	0.2834	0.5258	0.392	CHTOP/MCM2/SSBP1/SIRT1/IFIT1/POT1	6
BP	GO:0051798	positive regulation of hair follicle development	6/7096	12/18670	0.2834	0.5258	0.392	WNT5A/TNF/TRADD/HPSE/FOXN1/WNT10B	6
BP	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation	6/7096	12/18670	0.2834	0.5258	0.392	SMAD7/PBLD/LDLRAD4/PMEPA1/STRAP/GREM1	6
BP	GO:0071044	histone mRNA catabolic process	6/7096	12/18670	0.2834	0.5258	0.392	DCP2/ATM/MTPAP/XRN1/SSB/UPF1	6
BP	GO:0071073	positive regulation of phospholipid biosynthetic process	6/7096	12/18670	0.2834	0.5258	0.392	FPR2/HTR2B/CAPN2/FABP3/RAB38/NR1H4	6
BP	GO:0071481	cellular response to X-ray	6/7096	12/18670	0.2834	0.5258	0.392	XRCC5/ATM/DNM2/HAMP/XRCC6/NUCKS1	6
BP	GO:0071639	positive regulation of monocyte chemotactic protein-1 production	6/7096	12/18670	0.2834	0.5258	0.392	CLEC7A/IL1B/AGER/LGALS9/MCOLN2/TRPV4	6
BP	GO:0071888	macrophage apoptotic process	6/7096	12/18670	0.2834	0.5258	0.392	NOD2/IRF7/CCL5/SIRT1/CCR5/MEF2C	6
BP	GO:0072697	protein localization to cell cortex	6/7096	12/18670	0.2834	0.5258	0.392	EZR/SAPCD2/GPSM2/EPB41/EPB41L2/MISP	6
BP	GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress	6/7096	12/18670	0.2834	0.5258	0.392	TMBIM6/DNAJB1/NCK1/HIF1AN/CITED2/IMPACT	6
BP	GO:0097340	inhibition of cysteine-type endopeptidase activity	6/7096	12/18670	0.2834	0.5258	0.392	BIRC2/CAST/CST7/BIRC3/BIRC7/XIAP	6
BP	GO:0097341	zymogen inhibition	6/7096	12/18670	0.2834	0.5258	0.392	BIRC2/CAST/CST7/BIRC3/BIRC7/XIAP	6
BP	GO:0097531	mast cell migration	6/7096	12/18670	0.2834	0.5258	0.392	RAC2/VEGFB/SWAP70/VEGFA/RAC1/PIK3CD	6
BP	GO:0098885	modification of postsynaptic actin cytoskeleton	6/7096	12/18670	0.2834	0.5258	0.392	CTTNBP2/PFN1/BAIAP2/ITSN1/CYFIP1/RHOA	6
BP	GO:0099638	endosome to plasma membrane protein transport	6/7096	12/18670	0.2834	0.5258	0.392	RAB11A/GRIPAP1/GRIP1/RAB8A/GRASP/LRRC7	6
BP	GO:0150065	regulation of deacetylase activity	6/7096	12/18670	0.2834	0.5258	0.392	PINK1/VEGFA/LRRK2/MAPK8/PRKD2/CAMK2D	6
BP	GO:1900044	regulation of protein K63-linked ubiquitination	6/7096	12/18670	0.2834	0.5258	0.392	NOD2/BIRC2/PLAA/PTPN22/UBR5/SASH1	6
BP	GO:1902224	ketone body metabolic process	6/7096	12/18670	0.2834	0.5258	0.392	HMGCL/AACS/BDH1/BDH2/OXCT1/HMGCLL1	6
BP	GO:2000121	regulation of removal of superoxide radicals	6/7096	12/18670	0.2834	0.5258	0.392	GCH1/TNF/CD36/BMP7/NFE2L2/DHFR	6
BP	GO:2000232	regulation of rRNA processing	6/7096	12/18670	0.2834	0.5258	0.392	TRMT112/UTP15/DIMT1/WDR75/RIOK2/NUDT16	6
BP	GO:2001053	regulation of mesenchymal cell apoptotic process	6/7096	12/18670	0.2834	0.5258	0.392	HIF1A/PAX8/BMP7/HNF1B/MSX1/GDF5	6
BP	GO:0031032	actomyosin structure organization	80/7096	199/18670	0.2839	0.5266	0.3926	S100A10/PTGER4/STMN1/MEF2A/FHOD1/TSC1/ARAP1/SORBS3/ITGB5/RHOC/S1PR1/KLHL41/F11R/RGCC/AKAP13/SLC9A1/ARHGEF10L/TMOD3/EVL/PFN1/ARRB1/EPB41L1/PAK1/PHACTR1/PTK2B/CFL2/SRF/ACTC1/ABL1/MYBPC3/ALKBH4/PPM1F/MKKS/RAC1/ARHGAP6/MYH9/FRMD3/BBS4/LIMCH1/ZYX/CNN2/PGM5/NRP1/CAPN9/TPM1/INPP5K/CD47/OBSCN/KRT8/LPAR1/PXN/MYOZ1/CLASP2/LMOD3/CAV3/MYOM2/APOA1/EPB41/CASQ1/TGFB3/CAPN3/CASQ2/SYNPO2L/TACSTD2/TMEFF2/EPB41L2/CSRP1/MTOR/RHOA/ITGB1BP1/MET/MYH3/WAS/ROCK2/ACTA1/ASAP3/SERPINF2/TNNT1/ALMS1/MEF2C	80
BP	GO:0045669	positive regulation of osteoblast differentiation	27/7096	64/18670	0.2851	0.5285	0.394	IGF1/CLIC1/ACVR2B/ATP6AP1/JUND/SMAD5/ATRAID/CEBPB/IFITM1/LRP5/ZHX3/HGF/PDLIM7/CEBPA/BMP2/IL6ST/BMP7/IL6/BMPR1A/BMP4/SUCO/CTHRC1/TMEM119/WNT10B/BMPR1B/MEF2C/BMPR2	27
BP	GO:0050922	negative regulation of chemotaxis	27/7096	64/18670	0.2851	0.5285	0.394	DUSP1/WNT5A/SEMA4B/PTPN2/MIF/GSTP1/PTPRO/DUSP3/CXCL13/SEMA4A/AIF1/SEMA4C/SEMA4D/CORO1B/MIR34A/SEMA6B/NRP1/SEMA3B/GPR18/SEMA5A/SLIT2/SEMA5B/PLXNA3/HRG/C5AR2/GREM1/SLAMF8	27
BP	GO:0009452	7-methylguanosine RNA capping	15/7096	34/18670	0.2855	0.5285	0.394	CCNH/GTF2F2/POLR2L/POLR2H/RNGTT/GTF2H4/GTF2F1/CMTR1/POLR2F/POLR2D/TGS1/POLR2K/ERCC2/CMTR2/POLR2I	15
BP	GO:0033120	positive regulation of RNA splicing	15/7096	34/18670	0.2855	0.5285	0.394	TRA2B/SRSF5/DAZAP1/THRAP3/HABP4/ZPR1/RBMXL1/RBM3/SETX/PRDX6/SF3B4/PRPF19/CELF3/HMX2/ERN1	15
BP	GO:0036260	RNA capping	15/7096	34/18670	0.2855	0.5285	0.394	CCNH/GTF2F2/POLR2L/POLR2H/RNGTT/GTF2H4/GTF2F1/CMTR1/POLR2F/POLR2D/TGS1/POLR2K/ERCC2/CMTR2/POLR2I	15
BP	GO:0043276	anoikis	15/7096	34/18670	0.2855	0.5285	0.394	BMF/PDK4/ITGA5/SIK1/ZNF304/TLE1/IKBKG/MCL1/PTK2/MYBBP1A/BCL2/MTOR/DAPK2/NTRK2/BRMS1	15
BP	GO:0097755	positive regulation of blood vessel diameter	25/7096	59/18670	0.2862	0.5296	0.3949	KCNMB1/GCH1/SOD1/PPARD/RGS2/HMOX1/APOE/PTAFR/LEP/ADRB1/BBS2/MKKS/DOCK5/ADORA2B/ADRB2/SCPEP1/EGFR/PLA2G6/VIP/GPX1/KCNMA1/GJA1/PTPRM/APLN/BMPR2	25
BP	GO:0019932	second-messenger-mediated signaling	173/7096	439/18670	0.2862	0.5296	0.3949	IGF1/SLC8A1/FPR2/HTR2B/FPR1/CCR2/CX3CR1/PTGER4/S1PR4/ATP2B4/PRKAR2B/BST1/PPP2CA/AZU1/GBP1/CAMTA1/MCOLN1/PTGER2/CHP1/GNB1/CIB1/RGS2/LGR4/ACKR3/CXCL9/CXCL11/PTPRC/DEFB1/P2RX7/BCAP31/TNF/AKAP13/SLC9A1/CXCL10/DDAH2/PKD2/APOE/GSK3B/CD22/PDK2/DYRK2/ARRDC3/PPP3CB/NFATC3/LAT2/ITPR1/DGKD/FIS1/GNAQ/RAPGEF2/CD36/PTK2B/MYO5A/MAPK7/P2RY6/NRG1/MCU/SCTR/ADRB1/RCAN3/VEGFA/CMKLR1/ABCA1/GSTO1/HINT1/HOMER3/PLCG2/AHR/P2RY12/DMD/TRPM4/TRPM2/EIF4EBP2/ADCY7/CXCR1/LRRK2/GNG2/SPINK1/CCR5/TMBIM4/ADCY1/SRI/CRTC3/SPHK1/GPR62/NMUR2/TRAT1/ADORA2B/LMCD1/ADCY3/GNAI2/NFATC1/NFATC2/HDAC4/ATP1B1/CCR6/PRKACA/RCAN1/ADRB2/GPR143/CXCR6/CCR4/PDX1/PLEK/NFAT5/KSR2/GPR26/LPAR1/DMTN/ZMPSTE24/ADA/GRIN2C/MYOZ1/CAMK2D/CCR3/EGFR/CXCR2/CCL20/ATP2A2/FHL2/CALML3/GIPR/PRKAA1/GPHB5/GNA13/GALR1/LGR5/GPR61/CASQ1/TREM2/GPHA2/CASQ2/ADRA1D/HRC/HTR5A/EFHB/VIP/PTHLH/CHP2/GPRC6A/CD4/TMEM38B/FSHR/LACRT/GPR161/RXFP2/SLA2/OPRL1/MTOR/GHRH/IAPP/CXCR3/P2RX2/RIMS2/CHERP/GCG/CCL4/ATP1A2/RUNDC3A/CCR7/CD3E/UBE2B/ACKR2/ADCYAP1R1/CCRL2/PRKCA/UCN3/ERBB3/RASD2/LAT/INPP5A/PTPRJ/P2RX5	173
BP	GO:0001539	cilium or flagellum-dependent cell motility	17/7096	39/18670	0.287	0.5301	0.3952	LRRC6/CATSPER1/BBS2/RFX3/MKKS/BBS4/DNAH17/DNAAF2/RSPH9/CCDC65/RSPH6A/TTLL1/TEKT3/EFHC1/DNAH8/DNAH2/GAS8	17
BP	GO:0009072	aromatic amino acid family metabolic process	17/7096	39/18670	0.287	0.5301	0.3952	ASRGL1/IL4I1/PCBD1/HAL/HNMT/FAH/IDO1/GSTZ1/QDPR/KYNU/HAAO/DCT/TPH2/IDO2/AMDHD1/ATP7A/TDO2	17
BP	GO:0042769	DNA damage response, detection of DNA damage	17/7096	39/18670	0.287	0.5301	0.3952	RPA1/DDB1/POLD4/POLD2/RFC3/PCNA/USP1/UBC/DTL/POLD1/DNAJA1/CUL4B/RBX1/SOX4/MRPS9/UBE2B/PNKP	17
BP	GO:0060285	cilium-dependent cell motility	17/7096	39/18670	0.287	0.5301	0.3952	LRRC6/CATSPER1/BBS2/RFX3/MKKS/BBS4/DNAH17/DNAAF2/RSPH9/CCDC65/RSPH6A/TTLL1/TEKT3/EFHC1/DNAH8/DNAH2/GAS8	17
BP	GO:1901998	toxin transport	17/7096	39/18670	0.287	0.5301	0.3952	MTMR12/LRP5/HSPA5/CRTC2/RAB43/RAB29/DNM1/NRP1/SLC7A8/ABCG1/CD274/CCT4/CCT8/ANTXR2/DNAJA1/SCFD1/RAB28	17
BP	GO:0032210	regulation of telomere maintenance via telomerase	23/7096	54/18670	0.2871	0.5301	0.3952	MAP3K4/PKIB/NAF1/HNRNPA1/XRCC5/DCP2/NAT10/ATM/MAPKAPK5/HNRNPC/XRN1/CCT4/FBXO4/CCT8/ATR/MAPK1/ACD/CTC1/GNL3L/PRKCQ/POT1/PNKP/NEK7	23
BP	GO:0061512	protein localization to cilium	23/7096	54/18670	0.2871	0.5301	0.3952	SPATA7/TCTN1/SNX10/TULP3/ARF4/CSNK1D/ARL13B/WDR19/EHD1/RAB29/CCDC88A/ATP6V1D/BBS4/TCTN2/NPHP4/RABEP1/BBS9/IFT20/WDR35/TMEM107/TULP1/CCDC66/GAS8	23
BP	GO:0002686	negative regulation of leukocyte migration	21/7096	49/18670	0.2876	0.5302	0.3953	PTGER4/IL27RA/DUSP1/MIF/HMOX1/CXCL12/ABR/CD200R1/BCR/BMP5/GPR18/CD300A/GCSAM/RABGEF1/ADA/PLCB1/SLIT2/C5AR2/GREM1/HOXA7/SLAMF8	21
BP	GO:0061001	regulation of dendritic spine morphogenesis	19/7096	44/18670	0.2876	0.5302	0.3953	SIPA1L1/DNM3/ACTR2/LRP8/UBE3A/BAIAP2/CDK5/PAFAH1B1/CAPRIN1/KALRN/LRRK2/ARC/PDLIM5/CFL1/BHLHB9/DNM1L/RELN/SHANK3/CAMK2B	19
BP	GO:0061756	leukocyte adhesion to vascular endothelial cell	19/7096	44/18670	0.2876	0.5302	0.3953	KLF4/CCR2/CX3CR1/SELL/ITGB7/TNF/CXCL12/RELA/PTAFR/LEP/TRAF6/ITGA4/GCNT1/ETS1/SELPLG/MADCAM1/NFAT5/RHOA/MIR146A	19
BP	GO:0070266	necroptotic process	19/7096	44/18670	0.2876	0.5302	0.3953	BIRC2/LY96/FAS/TNF/TICAM1/TLR4/FZD9/CASP8/ARHGEF2/SPATA2/RBCK1/CYLD/BIRC3/MLKL/YBX3/DNM1L/FADD/TLR3/PYGL	19
BP	GO:0090311	regulation of protein deacetylation	19/7096	44/18670	0.2876	0.5302	0.3953	PINK1/SKI/BCL6/TGFB1/ZBTB7B/VEGFA/LRRK2/AKAP8/MAPK8/PRKD2/SPRED1/FRY/CAMK2D/PRKAA1/IFNG/JDP2/BEX4/TADA3/BRMS1	19
BP	GO:1902667	regulation of axon guidance	19/7096	44/18670	0.2876	0.5302	0.3953	WNT5A/SEMA4B/ZSWIM6/CXCL12/PTPRO/MEGF8/SEMA4A/VEGFA/SEMA4C/SEMA4D/MYCBP2/SEMA6B/NRP1/SEMA3B/SEMA5A/SLIT2/SEMA5B/PLXNA3/BMPR2	19
BP	GO:0010634	positive regulation of epithelial cell migration	69/7096	171/18670	0.288	0.5308	0.3957	GLIPR2/ANXA1/GRN/ARF6/ENPP2/WNT5A/PTGS2/RAB11A/CD40/CIB1/LGMN/SCARB1/HMOX1/ANXA3/TGFB1/PFN1/HIF1A/HSPB1/PTK2B/VEGFA/PLK2/ABL1/STAT5A/IQSEC1/HMGB1/PPM1F/SIRT1/GPI/MAPRE2/PDGFB/FGF1/DOCK5/SPARC/ETS1/HDAC7/NRP1/MMP9/ZNF580/PRKD2/BMP4/NRP2/BCAS3/CCR6/ITGA2/SEMA5A/ITGA3/CALR/NFE2L2/CLASP2/ADAM17/NUS1/ADAM9/INSL3/AAMP/IFNG/HBEGF/MAP4K4/MTOR/FOXP1/RTN4/ITGB1BP1/MET/AMOTL1/WNT7A/ROCK2/PRKCA/SASH1/BMPR2/MIR146A	69
BP	GO:0055092	sterol homeostasis	40/7096	97/18670	0.2886	0.5316	0.3964	FABP4/NPC2/SCARB1/SOAT1/CETP/APOE/LRP5/LIMA1/NR1H2/AKR1C1/ABCA1/LAMTOR1/LDLR/EHD1/SIRT1/DGAT2/FABP3/TMEM97/APOA5/MIR34A/MED13/LCAT/ABCG1/NR1H3/RALY/SREBF2/NFE2L1/INSIG1/MALL/IL18/CAV3/NUS1/COMMD9/APOA1/RORA/ABCD1/SEC24A/NR1H4/CD24/G6PC	40
BP	GO:0003014	renal system process	49/7096	120/18670	0.291	0.536	0.3996	PRKAR2B/AKR1B1/RAB11A/LGMN/PSAP/PRKACB/AKR1C3/PTPRO/MAGED2/WFS1/HBB/HYAL2/ADCY7/PDGFB/SULF2/ADCY1/BCR/EMP2/BCL2/ADCY3/GNAI2/BMP4/INPP5K/PRKACA/PCSK5/KCNQ1/CYBA/SLC4A5/ITGA3/F2R/RRM2B/AQP3/CHRNB2/SNX5/SLC4A1/HNF1A/CD34/SUCNR1/REN/OPRL1/XPNPEP3/KCNMA1/RHOA/ATP6V1B1/SPX/GJA1/SERPINF2/AVPR2/MCAM	49
BP	GO:0048639	positive regulation of developmental growth	74/7096	184/18670	0.2917	0.5372	0.4005	IGF1/FN1/EZR/DLL1/PLS1/RBPJ/PIM1/RAB11A/PPARD/PLAA/CXCL12/TWF2/PAK1/MEGF8/LEP/SRF/INSR/PARP2/VEGFA/TNFRSF12A/PAFAH1B1/GDI1/SEMA4D/ACACB/LRP1/CREB1/BBS2/IL7/BASP1/MKKS/CYFIP1/SERP1/ARX/BBS4/BMPR1A/NRP1/DISC1/BCL2/L1CAM/GPR21/LPAR3/IST1/NDEL1/YBX3/SEMA5A/HLX/PLCB1/MUL1/HEY2/ITSN2/HAMP/MAPK1/RASAL1/CAPN3/MAP3K13/RUFY3/SYT1/CPNE9/PIN1/SYT2/SYT4/MTOR/GHRH/CRABP2/RIMS2/GHR/PPIB/SMO/WT1/MACF1/TRPV2/GHRL/MEF2C/BMPR2	74
BP	GO:0001892	embryonic placenta development	36/7096	87/18670	0.293	0.5394	0.4021	JUNB/EPAS1/SOCS3/RBPJ/MAP2K1/CEBPB/PKD2/BPTF/HIF1A/VASH1/TFEB/CEBPA/ASCL2/CASP8/CDKN1C/HEY1/BMP7/PDGFB/PCDH12/DNAJB6/BMP5/SPINT1/GRB2/KRT8/FZD5/HES1/ARNT/PLCD1/EGFR/HEY2/MAPK1/ZNF568/SNAI1/GRHL2/E2F8/NRK	36
BP	GO:0055117	regulation of cardiac muscle contraction	34/7096	82/18670	0.2952	0.5425	0.4044	SLC8A1/ATP1A1/FLNA/SMAD7/RGS2/TNNI3K/SLC9A1/KCNE3/PDE4B/GSTO1/DMD/TRPM4/SUMO1/SRI/CTNNA3/HCN4/HDAC4/ATP1B1/PRKACA/RANGRF/KCNQ1/CAMK2D/DSC2/CAV3/ATP2A2/CASQ2/HRC/PKP2/EHD3/TMEM38B/PIK3CG/FGF13/ATP1A2/BIN1	34
BP	GO:0016101	diterpenoid metabolic process	45/7096	110/18670	0.2961	0.5425	0.4044	ALDH3A2/RBP1/SRD5A1/AKR1B1/PPARD/ALDH1A1/RDH10/ADH5/RETSAT/AKR1C3/APOE/DHRS3/DHRS9/LRP8/CYP1B1/RDH16/NAPEPLD/AKR1C1/CYP2S1/PLB1/LRP1/DGAT2/RDH12/CYP2D6/CYP1A2/CYP26B1/ALDH8A1/RDH5/SCPEP1/AKR1B10/ADH1B/EGFR/GPC2/APOA1/BCO2/CYP26A1/GPC4/SDC3/CRABP2/RLBP1/ADH7/CYP2C8/RBP4/PNPLA4/STRA6	45
BP	GO:0000097	sulfur amino acid biosynthetic process	8/7096	17/18670	0.2973	0.5425	0.4044	ADI1/MTR/APIP/MTRR/ENOPH1/MTAP/CTH/BHMT	8
BP	GO:0001675	acrosome assembly	8/7096	17/18670	0.2973	0.5425	0.4044	RFX2/AGFG1/PAFAH1B1/PLA2G3/TBC1D20/TXNDC8/ACRBP/TBPL1	8
BP	GO:0006474	N-terminal protein amino acid acetylation	8/7096	17/18670	0.2973	0.5425	0.4044	KAT2B/NAA20/NAA10/NAA40/NAA16/NAA15/SOX4/NAA60	8
BP	GO:0006825	copper ion transport	8/7096	17/18670	0.2973	0.5425	0.4044	SCO2/STEAP4/SLC31A2/ATOX1/STEAP3/ATP7B/CUTC/ATP7A	8
BP	GO:0010224	response to UV-B	8/7096	17/18670	0.2973	0.5425	0.4044	CRIP1/CDKN1A/ERCC6/RELA/HYAL2/BCL2/HYAL3/IL12B	8
BP	GO:0010715	regulation of extracellular matrix disassembly	8/7096	17/18670	0.2973	0.5425	0.4044	CST3/DPP4/TGFB1/LRP1/IL6/ETS1/CLASP2/FSCN1	8
BP	GO:0010819	regulation of T cell chemotaxis	8/7096	17/18670	0.2973	0.5425	0.4044	CCR2/OXSR1/WNT5A/CXCL10/CXCL13/CCL5/TMEM102/ADAM17	8
BP	GO:0015919	peroxisomal membrane transport	8/7096	17/18670	0.2973	0.5425	0.4044	PEX12/PEX16/PEX13/PEX3/PEX19/RAB8B/PEX14/ABCD1	8
BP	GO:0016254	preassembly of GPI anchor in ER membrane	8/7096	17/18670	0.2973	0.5425	0.4044	PIGV/PIGP/PIGN/PIGF/PIGB/PIGM/PIGQ/PIGH	8
BP	GO:0018904	ether metabolic process	8/7096	17/18670	0.2973	0.5425	0.4044	EPHX1/TMEM86A/AGPS/TMEM86B/FAR1/TXN/GNPAT/CYP2W1	8
BP	GO:0021783	preganglionic parasympathetic fiber development	8/7096	17/18670	0.2973	0.5425	0.4044	ADARB1/EGR2/NRP1/NRP2/HES1/HOXB1/PLXNA3/NAV2	8
BP	GO:0031000	response to caffeine	8/7096	17/18670	0.2973	0.5425	0.4044	SLC8A1/RYR1/PPARGC1A/HDAC2/PRKAA1/CASQ2/CAD/TMEM38B	8
BP	GO:0031643	positive regulation of myelination	8/7096	17/18670	0.2973	0.5425	0.4044	RNF10/HGF/S100B/ZNF488/CST7/DICER1/SLC25A12/DAG1	8
BP	GO:0036158	outer dynein arm assembly	8/7096	17/18670	0.2973	0.5425	0.4044	LRRC6/DNAL1/DNAI2/CCDC151/DNAI1/LRRC61/CCDC63/DNAH8	8
BP	GO:0036270	response to diuretic	8/7096	17/18670	0.2973	0.5425	0.4044	SLC8A1/RYR1/PPARGC1A/HDAC2/PRKAA1/CASQ2/CAD/TMEM38B	8
BP	GO:0042994	cytoplasmic sequestering of transcription factor	8/7096	17/18670	0.2973	0.5425	0.4044	KEAP1/G3BP2/NFKBIA/PKD2/SRI/NFKBIE/MXI1/TONSL	8
BP	GO:0043651	linoleic acid metabolic process	8/7096	17/18670	0.2973	0.5425	0.4044	GSTP1/ELOVL5/CYP2J2/GSTA1/PNPLA8/ALOX15B/ABCD1/FADS2	8
BP	GO:0046500	S-adenosylmethionine metabolic process	8/7096	17/18670	0.2973	0.5425	0.4044	AHCY/APIP/MTRR/ENOPH1/GAMT/AHCYL2/AHCYL1/MAT1A	8
BP	GO:0061298	retina vasculature development in camera-type eye	8/7096	17/18670	0.2973	0.5425	0.4044	ACVR2B/LRP5/CYP1B1/HIF1A/NRP1/FZD4/BMPR2/LAMA1	8
BP	GO:0062033	positive regulation of mitotic sister chromatid segregation	8/7096	17/18670	0.2973	0.5425	0.4044	SMC5/NSMCE2/ESPL1/ANAPC5/DLGAP5/ANAPC4/RB1/ANAPC11	8
BP	GO:0070131	positive regulation of mitochondrial translation	8/7096	17/18670	0.2973	0.5425	0.4044	UQCC1/UQCC2/COA3/C1QBP/NGRN/RPUSD3/TRMT10C/MPV17L2	8
BP	GO:0072673	lamellipodium morphogenesis	8/7096	17/18670	0.2973	0.5425	0.4044	SNX1/ENPP2/CD44/PLEKHO1/ARPIN/CORO1B/KANK1/CORO1C	8
BP	GO:0098856	intestinal lipid absorption	8/7096	17/18670	0.2973	0.5425	0.4044	LIMA1/CD36/LEP/AKR1C1/LDLR/APOA5/UGCG/APOA1	8
BP	GO:0098884	postsynaptic neurotransmitter receptor internalization	8/7096	17/18670	0.2973	0.5425	0.4044	DNM3/USP46/OPHN1/NUMB/ARC/DNM1/DNM2/GSG1L	8
BP	GO:0140239	postsynaptic endocytosis	8/7096	17/18670	0.2973	0.5425	0.4044	DNM3/USP46/OPHN1/NUMB/ARC/DNM1/DNM2/GSG1L	8
BP	GO:1900363	regulation of mRNA polyadenylation	8/7096	17/18670	0.2973	0.5425	0.4044	ZC3H14/CDK9/SNRPA/CPEB1/CPEB3/RNF20/CCNT1/CPSF7	8
BP	GO:1901524	regulation of mitophagy	8/7096	17/18670	0.2973	0.5425	0.4044	PINK1/RNF41/CDC37/HTRA2/VPS13D/USP30/CLEC16A/OPTN	8
BP	GO:1903975	regulation of glial cell migration	8/7096	17/18670	0.2973	0.5425	0.4044	CCR2/CX3CR1/CERS2/P2RY12/LRP1/IDH2/TREM2/GPR183	8
BP	GO:2000811	negative regulation of anoikis	8/7096	17/18670	0.2973	0.5425	0.4044	PDK4/ITGA5/ZNF304/TLE1/MCL1/PTK2/BCL2/NTRK2	8
BP	GO:0033138	positive regulation of peptidyl-serine phosphorylation	43/7096	105/18670	0.2987	0.5449	0.4062	ATP2B4/PINK1/MAD2L2/WNT5A/SH2D3C/PTGS2/MIF/CD44/TNF/ERCC6/HCLS1/TGFB1/ARRB1/PAK1/LATS1/VEGFA/ARAF/RAF1/CREBL2/IL6/SMYD3/TNKS1BP1/BCAR3/FNIP1/BCL2/PRKD2/IFNK/OSM/EGFR/TXN/SPRY2/EIF4G1/IFNG/RET/OPRD1/MAPKAP1/HSP90AB1/TRIM6/APP/SNCA/PDCD10/GCG/NTRK2	43
BP	GO:0061180	mammary gland epithelium development	30/7096	72/18670	0.2995	0.5459	0.407	VDR/WNT5A/STAT6/CEBPB/JAK2/LRP5/TGFB1/HIF1A/LATS1/PML/CCND1/ETV5/ZNF703/BAX/ID2/KDM5B/MST1/ORAI1/CAV3/MAPK1/MSX1/ELF5/GPX1/CSF1R/RTN4/MGMT/FOXF1/SMO/LBH/PTCH1	30
BP	GO:1903051	negative regulation of proteolysis involved in cellular protein catabolic process	30/7096	72/18670	0.2995	0.5459	0.407	DDRGK1/LAMP3/HFE/FHIT/RYBP/CSNK2A2/ALAD/SGTA/OPHN1/SDCBP/UBE2J1/PML/UCHL5/UBE2G2/KLHL40/DERL2/YOD1/USP7/MAP1A/WNT1/PSEN1/UBXN1/OGT/HSP90AB1/CLEC16A/BAG5/USP19/SMARCC1/ERLEC1/OS9	30
BP	GO:0009855	determination of bilateral symmetry	52/7096	128/18670	0.2995	0.5459	0.407	DLL1/ACVR2B/WNT5A/DISP1/BBS5/AP1B1/SMAD2/LRRC6/SETDB2/IFT172/PKD2/IFT57/MIB1/KIF3B/HIF1A/MEGF8/ARL13B/SRF/DPCD/MICAL2/PSKH1/RFX3/MKKS/MESP1/IFT52/CITED2/BBS4/DNAI2/DYNC2LI1/BBS7/PCSK5/MKS1/CCDC151/C9orf116/CFC1/PCSK6/PSEN1/DNAI1/ENG/IFT74/AIDA/FOXF1/NEK8/CER1/GJA1/GREM1/SMO/DAAM2/C2CD3/GAS8/MEF2C/FOXH1	52
BP	GO:0048660	regulation of smooth muscle cell proliferation	68/7096	169/18670	0.3	0.5466	0.4075	KLF4/IGF1/NAMPT/CDKN1A/AKR1B1/GNAI3/PTGS2/PPARD/TNFAIP3/S1PR1/STAT1/JAK2/GSTP1/IL15/TNF/HMOX1/SKP2/HMGCR/NOTCH3/NDRG2/IRAK4/PTAFR/PAK1/HPGD/P2RY6/TRAF6/AIF1/XRCC5/CCL5/IL6/PDGFB/PPARGC1A/MIR34A/BMPR1A/MMP9/GNAI2/BMP4/TPM1/TGM2/HDAC4/ID2/CDKN1B/ITGA2/CYBA/MAP3K5/EGFR/IL18/MDM2/TCF7L2/XRCC6/TGFB3/IFNG/VIP/NR4A3/HBEGF/IL12B/ABCC4/MMP2/TERT/MTOR/FOXP1/ERN1/CX3CL1/PDCD4/SERPINF2/PDGFD/MEF2C/APLN	68
BP	GO:0048747	muscle fiber development	28/7096	67/18670	0.3015	0.5491	0.4094	MYOF/SKI/UCHL1/KLHL41/RYR1/VEGFA/MYBPC3/DMD/AFG3L2/HOMER1/MYOG/BCL2/BMP4/HDAC4/KLHL40/ZMPSTE24/LMOD3/BIN3/MYOM2/SHOX2/DNER/GPX1/P2RX2/WNT10B/ACTA1/SMO/KEL/MYF6	28
BP	GO:0035264	multicellular organism growth	59/7096	146/18670	0.3016	0.5491	0.4094	IGF1/KLF2/EZR/APBA1/PLS1/SOD1/STAT3/SLC25A25/PLEKHA1/PLAC8/LGMN/ATF5/ERCC6/GIGYF2/CDK4/SGPL1/HEG1/RBBP6/WDR11/HTRA2/ADARB1/ADRB1/STAT5A/PALB2/ATRN/CDKN1C/CREB1/BBS2/AFG3L2/MKKS/MBD5/PLAG1/ATM/BBS4/FTO/TARBP2/BCL2/GPR21/ERCC1/RMI1/ADRB2/GAMT/ZMPSTE24/ANKRD11/KAT2A/ERCC2/SPTBN2/MTOR/APP/GHRH/GHR/PPIB/SOCS2/SMO/G6PC/PTCH1/GRHL2/GHRL/GDF5	59
BP	GO:1904892	regulation of STAT cascade	59/7096	146/18670	0.3016	0.5491	0.4094	IGF1/FYN/SOCS3/LYN/PPP2CA/PARP9/AKR1B1/STAT3/PTPN2/MGAT5/ADIPOR1/CD40/JAK2/PTPRC/IL15/TNF/ERCC6/DOT1L/IL7R/HCLS1/CYP1B1/PTK2B/LEP/FLT3/CDK5/NLK/PTK6/CCL5/TNFRSF18/IL6ST/IL6/HDAC2/CLCF1/IFNK/OSM/HGS/DAB1/CD300A/INPP5F/HES1/F2R/PWP1/CNTF/CNOT7/IL18/SOCS1/IL3/TSLP/IFNG/TNFSF18/RET/IL12B/CSF1R/ARL2BP/GHR/IL26/SOCS2/IL23A/MIR146A	59
BP	GO:1904356	regulation of telomere maintenance via telomere lengthening	26/7096	62/18670	0.3035	0.5522	0.4117	ERCC4/MAP3K4/PKIB/NAF1/HNRNPA1/HNRNPA2B1/XRCC5/DCP2/NAT10/ATM/MAPKAPK5/HNRNPC/XRN1/CCT4/FBXO4/CCT8/ATR/MAPK1/RTEL1/ACD/CTC1/GNL3L/PRKCQ/POT1/PNKP/NEK7	26
BP	GO:0002052	positive regulation of neuroblast proliferation	10/7096	22/18670	0.3043	0.5522	0.4117	CX3CR1/HIF1A/VEGFA/ASPM/DISC1/DCT/CX3CL1/OTP/SMO/ZNF335	10
BP	GO:0002097	tRNA wobble base modification	10/7096	22/18670	0.3043	0.5522	0.4117	DPH3/ALKBH1/ELP4/ELP3/ALKBH8/MOCS3/ELP2/ADAT2/MTO1/GTPBP3	10
BP	GO:0035024	negative regulation of Rho protein signal transduction	10/7096	22/18670	0.3043	0.5522	0.4117	STMN1/BCL6/KCTD10/HEG1/FLCN/SCAI/KANK1/ITGA3/ABL2/MET	10
BP	GO:0042359	vitamin D metabolic process	10/7096	22/18670	0.3043	0.5522	0.4117	VDR/CYP27A1/LGMN/TNF/NFKB1/IL1B/CYP27B1/SNAI1/IFNG/FGF23	10
BP	GO:0045663	positive regulation of myoblast differentiation	10/7096	22/18670	0.3043	0.5522	0.4117	CXCL9/FLT3LG/HIF1AN/BTG1/MYOG/MAP3K5/PLCB1/BOC/MEF2C/MYF6	10
BP	GO:0051457	maintenance of protein location in nucleus	10/7096	22/18670	0.3043	0.5522	0.4117	SUN2/BARD1/SUPT7L/CDK5/SP100/PML/BBS4/TXN/TOPORS/ARL2BP	10
BP	GO:0071379	cellular response to prostaglandin stimulus	10/7096	22/18670	0.3043	0.5522	0.4117	PTGER4/PTGER2/GNB1/AKR1C3/P2RY6/GNG2/AKAP8/TNFSF4/PRKAA1/P2RY4	10
BP	GO:0090189	regulation of branching involved in ureteric bud morphogenesis	10/7096	22/18670	0.3043	0.5522	0.4117	LGR4/MAGED1/TGFB1/VEGFA/PAX8/BMP4/HNF1B/TACSTD2/WNT2B/SMO	10
BP	GO:0097205	renal filtration	10/7096	22/18670	0.3043	0.5522	0.4117	PTPRO/PDGFB/SULF2/EMP2/ITGA3/F2R/CD34/XPNPEP3/GJA1/MCAM	10
BP	GO:2001032	regulation of double-strand break repair via nonhomologous end joining	10/7096	22/18670	0.3043	0.5522	0.4117	USP51/MAD2L2/PARP9/SETMAR/SMCHD1/NUDT16L1/DTX3L/PARP3/KDM4D/AUNIP	10
BP	GO:0001755	neural crest cell migration	24/7096	57/18670	0.3053	0.5536	0.4127	HTR2B/FN1/SEMA4B/KITLG/ZEB2/HIF1A/SEMA4A/SEMA4C/SEMA4D/EFNB1/BMP7/SEMA6B/NRP1/SEMA3B/ANXA6/BMP4/NRP2/CFL1/SEMA5A/CORO1C/SEMA5B/RET/PHACTR4/SMO	24
BP	GO:0002066	columnar/cuboidal epithelial cell development	24/7096	57/18670	0.3053	0.5536	0.4127	DLL1/CDKN1A/WNT5A/SOD1/GSK3B/HIF1A/PAFAH1B1/RFX3/BMP5/BMP4/WDPCP/TRIOBP/KLF5/TYMS/CLOCK/SLC4A7/BAD/YIPF6/ARNTL/LRTOMT/C1GALT1/SIDT2/TMC1/SMO	24
BP	GO:0071398	cellular response to fatty acid	24/7096	57/18670	0.3053	0.5536	0.4127	PTGER4/PDK4/PTGER2/GNB1/AKR1C3/CDK4/PTAFR/FFAR2/P2RY6/XRCC5/LDLR/CREB1/DGAT2/GNG2/PPARGC1A/AKAP8/NME1/CPT1A/UCP1/TNFSF4/PRKAA1/PID1/P2RY4/NR1H4	24
BP	GO:0001843	neural tube closure	37/7096	90/18670	0.3067	0.5556	0.4142	VASP/BCL10/SKI/WNT5A/TSC1/IFT172/DVL2/PRKACB/IFT57/ZEB2/PLXNB2/TGFB1/TULP3/PFN1/TRAF6/FUZ/CASP3/ABL1/SEMA4C/GLMN/BBS4/BMP4/KDM2B/KIF20B/PRKACA/SPINT1/MKS1/TEAD2/FZD1/DVL1/KAT2A/CTHRC1/PHACTR4/FZD2/GRHL3/PTCH1/GRHL2	37
BP	GO:0045778	positive regulation of ossification	37/7096	90/18670	0.3067	0.5556	0.4142	IGF1/SLC8A1/CLIC1/ACVR2B/WNT5A/ATP6AP1/JUND/SMAD5/ATRAID/CEBPB/P2RX7/IFITM1/LRP5/ZHX3/TGFB1/HGF/PDLIM7/FZD9/CEBPA/BMP2/ISG15/IL6ST/BMP7/IL6/BMPR1A/BMP4/ADRB2/SUCO/KL/CTHRC1/TGFB3/ZBTB16/TMEM119/WNT10B/BMPR1B/MEF2C/BMPR2	37
BP	GO:0009651	response to salt stress	12/7096	27/18670	0.3078	0.5556	0.4142	AKR1B1/TNF/XRCC5/EFHD1/BAX/MICU1/LETM1/XRCC6/CAPN3/HSP90AB1/TRPV4/SLC12A6	12
BP	GO:0022616	DNA strand elongation	12/7096	27/18670	0.3078	0.5556	0.4142	GINS1/POLD2/RFC3/RNASEH1/PCNA/GINS4/POLA1/TERT/LIG3/POT1/NUCKS1/FEN1	12
BP	GO:0031167	rRNA methylation	12/7096	27/18670	0.3078	0.5556	0.4142	TFB1M/TRMT112/TRMT61B/FBL/FTSJ3/FDXACB1/DIMT1/ZCCHC4/METTL15/MRM1/FBLL1/NSUN5P1	12
BP	GO:0032673	regulation of interleukin-4 production	12/7096	27/18670	0.3078	0.5556	0.4142	NLRP3/CEBPB/IL20RB/HLA-E/SCGB1A1/LGALS9/TNFSF4/HAVCR2/PRKCZ/PRKCQ/CD83/CD3E	12
BP	GO:0036151	phosphatidylcholine acyl-chain remodeling	12/7096	27/18670	0.3078	0.5556	0.4142	LPCAT2/PLA2G12A/PLBD1/PLB1/PNPLA8/PLA2G3/MBOAT2/TMEM86B/DBI/PLA2G6/LPCAT1/LPCAT3	12
BP	GO:0043921	modulation by host of viral transcription	12/7096	27/18670	0.3078	0.5556	0.4142	CHD1/TFAP4/TAF11/CCL5/CTDP1/PSMC3/INPP5K/HPN/CCNT1/CCL4/NUCKS1/TARDBP	12
BP	GO:0048643	positive regulation of skeletal muscle tissue development	12/7096	27/18670	0.3078	0.5556	0.4142	DLL1/FLOT1/HMGCR/MYOG/BCL2/CYP26B1/LMOD3/PRKAA1/SHOX2/ARNTL/MEF2C/MYF6	12
BP	GO:0048799	animal organ maturation	12/7096	27/18670	0.3078	0.5556	0.4142	IGF1/DCHS1/THBS3/LEP/RYR1/BMP2/XYLT1/SEMA4D/RET/MBTPS2/RHOA/GREM1	12
BP	GO:0052472	modulation by host of symbiont transcription	12/7096	27/18670	0.3078	0.5556	0.4142	CHD1/TFAP4/TAF11/CCL5/CTDP1/PSMC3/INPP5K/HPN/CCNT1/CCL4/NUCKS1/TARDBP	12
BP	GO:0061437	renal system vasculature development	12/7096	27/18670	0.3078	0.5556	0.4142	EGR1/PKD2/NOTCH3/ACTA2/BMP7/PDGFB/NRP1/BMP4/HES1/CD34/WT1/PDGFD	12
BP	GO:0061440	kidney vasculature development	12/7096	27/18670	0.3078	0.5556	0.4142	EGR1/PKD2/NOTCH3/ACTA2/BMP7/PDGFB/NRP1/BMP4/HES1/CD34/WT1/PDGFD	12
BP	GO:0071450	cellular response to oxygen radical	12/7096	27/18670	0.3078	0.5556	0.4142	NQO1/GCH1/SOD1/TNF/CD36/PRDX1/ADPRHL2/BMP7/NFE2L2/DHFR/ATP7A/MPO	12
BP	GO:0071451	cellular response to superoxide	12/7096	27/18670	0.3078	0.5556	0.4142	NQO1/GCH1/SOD1/TNF/CD36/PRDX1/ADPRHL2/BMP7/NFE2L2/DHFR/ATP7A/MPO	12
BP	GO:1905208	negative regulation of cardiocyte differentiation	12/7096	27/18670	0.3078	0.5556	0.4142	DLL1/RGS2/PAK1/BMP2/CTDP1/G6PD/YY1/EGFR/PPARA/CAV3/HEY2/FZD7	12
BP	GO:0006953	acute-phase response	20/7096	47/18670	0.3082	0.5556	0.4142	SERPINA1/FN1/STAT3/PTGS2/PLSCR1/CEBPB/HFE/TNF/IL1B/TNFRSF11A/IL6/APOL2/IL1A/HAMP/SIGIRR/REG3G/HP/LBP/SERPINF2/APCS	20
BP	GO:0045023	G0 to G1 transition	20/7096	47/18670	0.3082	0.5556	0.4142	CBX5/EZH2/RYBP/PCGF2/E2F6/RBBP7/MGA/RBBP4/HLA-G/RHNO1/CBX3/RRM2/FOXO4/RING1/BRCA1/EPC1/PHC1/PPP2R5B/YAF2/UXT	20
BP	GO:0045646	regulation of erythrocyte differentiation	20/7096	47/18670	0.3082	0.5556	0.4142	SPI1/LYN/ZFP36/STAT3/STAT1/LDB1/FAM210B/HIF1A/ISG15/KLF13/ACVR1B/TAL1/ETS1/HMGB2/ID2/INHBA/ARNT/TRIM58/PRMT1/FOXO3	20
BP	GO:0006284	base-excision repair	18/7096	42/18670	0.3092	0.5556	0.4142	ERCC6/NEIL2/UNG/RPA1/PARP2/HMGA1/TDG/POLG/PCNA/XRCC1/LOC100133315/POLL/POLD1/LIG3/POLB/FEN1/MBD4/SMUG1	18
BP	GO:0031641	regulation of myelination	18/7096	42/18670	0.3092	0.5556	0.4142	TYMP/RNF10/CTSC/TNFRSF21/HGF/FIG4/ZPR1/S100B/ZNF488/CST7/DICER1/SLC25A12/MTMR2/LGI4/MTOR/DAG1/PTPRZ1/KIF14	18
BP	GO:0032958	inositol phosphate biosynthetic process	18/7096	42/18670	0.3092	0.5556	0.4142	PTAFR/IP6K1/PTK2B/P2RY6/PLCG2/PPIP5K2/PLCL1/PLEK/PLCD1/PLCB1/IPPK/PLCD4/PLCL2/SNCA/CD244/ADCYAP1R1/P2RY1/NTSR1	18
BP	GO:0042181	ketone biosynthetic process	18/7096	42/18670	0.3092	0.5556	0.4142	EGR1/AKR1C3/TPI1/COQ7/COQ5/BMP2/PDSS1/COQ3/PPARGC1A/BMP5/SIRT5/COQ10B/COQ9/COQ6/HSD17B3/COQ10A/COQ4/CACNA1H	18
BP	GO:0008608	attachment of spindle microtubules to kinetochore	14/7096	32/18670	0.3093	0.5556	0.4142	SEH1L/CENPE/SPAG5/MIS12/ZNF207/CENPC/CHAMP1/BUB3/NDC80/NUF2/RCC2/KIF2C/RB1/BOD1	14
BP	GO:0009261	ribonucleotide catabolic process	14/7096	32/18670	0.3093	0.5556	0.4142	ACOT7/HDDC3/PDE4B/HINT1/NUDT9/MLYCD/NUDT3/PDE7A/NUDT7/PDE8A/AMPD3/ABCD1/NUDT16/PDE8B	14
BP	GO:0031297	replication fork processing	14/7096	32/18670	0.3093	0.5556	0.4142	ALYREF/ETAA1/SETMAR/SAMHD1/CDK9/PCNA/BOD1L1/RFWD3/GEN1/FANCM/RTEL1/TONSL/NUCKS1/ZRANB3	14
BP	GO:0038128	ERBB2 signaling pathway	14/7096	32/18670	0.3093	0.5556	0.4142	GAB1/CDC37/NRG1/PTK6/SHC1/GRB2/GRB7/STUB1/EGFR/MATK/CPNE3/HBEGF/PRKCA/ERBB3	14
BP	GO:0042491	inner ear auditory receptor cell differentiation	14/7096	32/18670	0.3093	0.5556	0.4142	DLL1/RBPJ/SOD1/PAFAH1B1/WDPCP/TRIOBP/HES1/HEY2/SLC4A7/POU4F3/LRTOMT/TMC1/MCOLN3/MYCL	14
BP	GO:0042573	retinoic acid metabolic process	14/7096	32/18670	0.3093	0.5556	0.4142	RBP1/RDH10/AKR1C3/DHRS9/CYP2S1/CYP26B1/ALDH8A1/SCPEP1/ADH1B/BCO2/CYP26A1/CRABP2/ADH7/CYP2C8	14
BP	GO:0060674	placenta blood vessel development	14/7096	32/18670	0.3093	0.5556	0.4142	JUNB/SOCS3/RBPJ/MAP2K1/PKD2/VASH1/HEY1/SPINT1/FZD5/HES1/PLCD1/HEY2/MAPK1/FOSL1	14
BP	GO:1900745	positive regulation of p38MAPK cascade	14/7096	32/18670	0.3093	0.5556	0.4142	MAP3K4/GADD45B/LEP/NCF1/BMP2/VEGFA/IL1B/AGER/MFHAS1/RELL2/SPHK1/MAP3K5/PRMT1/SASH1	14
BP	GO:1901976	regulation of cell cycle checkpoint	14/7096	32/18670	0.3093	0.5556	0.4142	DUSP1/DYNC1LI1/RNASEH2B/FEM1B/ETAA1/CDK5RAP2/LCMT1/NDC80/RFWD3/GEN1/THOC5/FBXO4/PCID2/WDR76	14
BP	GO:1902235	regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	14/7096	32/18670	0.3093	0.5556	0.4142	ERP29/PTPN2/TMBIM6/PMAIP1/WFS1/NCK1/SIRT1/LRRK2/BCL2L11/TXNDC12/SERINC3/CREB3/PDX1/HYOU1	14
BP	GO:0014031	mesenchymal cell development	35/7096	85/18670	0.3094	0.5556	0.4142	HTR2B/FN1/SEMA4B/KLHL12/KITLG/RDH10/ZEB2/HIF1A/NRG1/SEMA4A/SEMA4C/SEMA4D/EFNB1/BMP7/NOLC1/SEMA6B/KBTBD8/BMPR1A/NRP1/SEMA3B/ANXA6/BCL2/BMP4/NRP2/CFL1/PEF1/SEMA5A/HES1/CORO1C/HEY2/SEMA5B/MAPK1/RET/PHACTR4/SMO	35
BP	GO:0043243	positive regulation of protein complex disassembly	16/7096	37/18670	0.3097	0.5556	0.4142	TNF/CFL2/INSR/IGF1R/SETX/CFL1/ADRB2/PLEK/SEMA5A/EIF5A/SMCR8/KATNB1/CLEC16A/JMJD4/TRPV4/SLN	16
BP	GO:0060323	head morphogenesis	16/7096	37/18670	0.3097	0.5556	0.4142	CSRNP1/SKI/PLEKHA1/RRAS/TGFB1/SGPL1/CRISPLD2/RAB3GAP1/ATP6AP2/TIPARP/ANKRD11/TGFB3/MSX1/MMP2/MYH3/STRA6	16
BP	GO:0071276	cellular response to cadmium ion	16/7096	37/18670	0.3097	0.5556	0.4142	FOS/SOD1/HMOX1/AKR1C3/NCF1/SUMO1/CYP1A2/MAPK8/MMP9/CYBB/EGFR/MAPK1/ATP7A/CHUK/DAXX/MAPK9	16
BP	GO:2000273	positive regulation of signaling receptor activity	16/7096	37/18670	0.3097	0.5556	0.4142	CCR2/PINK1/FBXW7/HFE/EPHB2/NCOA3/NCF1/BUD31/TAL1/ARC/ADRB2/ADAM17/IFNG/RELN/GREM1/SHANK3	16
BP	GO:0046916	cellular transition metal ion homeostasis	44/7096	108/18670	0.3109	0.5578	0.4158	S100A9/S100A8/SLC40A1/SCO2/SLC11A1/SOD1/ATP6AP1/NCOA4/CUL1/MYC/HFE/SLC31A2/HMOX1/ATOX1/FBXL5/CYBRD1/HIF1A/FTL/ISCU/COX19/ABCB6/TTC7A/ATP6V1A/SLC39A10/SLC39A8/ACO1/ATP7B/SLC39A13/LCK/SLC39A7/SRI/ARF1/GLRX3/CAND1/SLC46A1/IREB2/SLC39A12/TFRC/HAMP/ATP7A/SLC30A2/APP/SLC30A9/ABCB7	44
BP	GO:1902106	negative regulation of leukocyte differentiation	42/7096	103/18670	0.3139	0.5603	0.4177	ANXA1/LYN/IRF1/PTPN2/BCL6/LILRB3/SMAD7/FGL2/FBXW7/MYC/IL4R/CBFB/CD74/LILRB1/SOCS5/LILRB4/TLR4/ZBTB7B/DTX1/NFKBID/HMGB1/HLA-G/CTLA4/NRARP/BMP4/ID2/NME1/LAG3/INHBA/PGLYRP4/HLX/PIAS3/TNFSF4/LRRC17/SOCS1/C1QC/CLDN18/TLR3/INHA/TBX21/HOXA7/APCS	42
BP	GO:0032482	Rab protein signal transduction	31/7096	75/18670	0.3148	0.5603	0.4177	RAB9A/RAB11A/DENND1A/RAB31/RAB23/RAB24/GDI1/RAB20/RAB8A/RAB43/RAB33B/RAB29/RAB32/RAB38/RAB5C/RAB39B/RAB5A/RAB7B/RAB8B/RAB22A/RAB3A/RAB35/RAB3B/IFT22/DENND4B/RAB33A/RAB3D/RAB27A/RAB26/RAB36/RAB28	31
BP	GO:0043242	negative regulation of protein complex disassembly	31/7096	75/18670	0.3148	0.5603	0.4177	CIB1/TNF/IRAK3/TMOD3/LIMA1/TWF2/RDX/CAPZA2/SWAP70/CAPG/ARHGEF2/CAPZA1/SPTBN1/SCAF8/PHF23/AVIL/TRIOBP/ADD3/DMTN/CLASP2/LMOD3/SCIN/SCAF4/KATNB1/SPTA1/SPTBN2/CLEC16A/NAV3/TTBK2/SLN/FGF13	31
BP	GO:0000338	protein deneddylation	5/7096	10/18670	0.3178	0.5603	0.4177	TOR1A/COPS2/COPS8/GPS1/COPS3	5
BP	GO:0001660	fever generation	5/7096	10/18670	0.3178	0.5603	0.4177	PTGS2/TNF/IL1B/TNFRSF11A/IL1A	5
BP	GO:0006188	IMP biosynthetic process	5/7096	10/18670	0.3178	0.5603	0.4177	PAICS/ATIC/PPAT/AMPD2/AMPD3	5
BP	GO:0006285	base-excision repair, AP site formation	5/7096	10/18670	0.3178	0.5603	0.4177	NEIL2/UNG/TDG/MBD4/SMUG1	5
BP	GO:0006307	DNA dealkylation involved in DNA repair	5/7096	10/18670	0.3178	0.5603	0.4177	ASCC3/ALKBH1/FTO/ALKBH2/MGMT	5
BP	GO:0006569	tryptophan catabolic process	5/7096	10/18670	0.3178	0.5603	0.4177	IDO1/KYNU/HAAO/IDO2/TDO2	5
BP	GO:0006971	hypotonic response	5/7096	10/18670	0.3178	0.5603	0.4177	OXSR1/ITGA2/MYLK/TRPV4/SLC12A6	5
BP	GO:0010944	negative regulation of transcription by competitive promoter binding	5/7096	10/18670	0.3178	0.5603	0.4177	MAD2L2/SMAD7/KDM2A/CREB1/MUC1	5
BP	GO:0014049	positive regulation of glutamate secretion	5/7096	10/18670	0.3178	0.5603	0.4177	P2RX7/STXBP1/RAB3GAP1/SYT4/NTSR1	5
BP	GO:0014877	response to muscle inactivity involved in regulation of muscle adaptation	5/7096	10/18670	0.3178	0.5603	0.4177	MYOG/MTMR4/HDAC4/CASQ1/DAG1	5
BP	GO:0014894	response to denervation involved in regulation of muscle adaptation	5/7096	10/18670	0.3178	0.5603	0.4177	MYOG/MTMR4/HDAC4/CASQ1/DAG1	5
BP	GO:0015801	aromatic amino acid transport	5/7096	10/18670	0.3178	0.5603	0.4177	SLC38A7/SLC7A5/SLC16A10/SLC36A4/OCA2	5
BP	GO:0015809	arginine transport	5/7096	10/18670	0.3178	0.5603	0.4177	SLC11A1/CLN3/SLC7A1/SLC7A2/SLC38A9	5
BP	GO:0021694	cerebellar Purkinje cell layer formation	5/7096	10/18670	0.3178	0.5603	0.4177	LDB1/RORA/FAIM2/ATP7A/AGTPBP1	5
BP	GO:0030311	poly-N-acetyllactosamine biosynthetic process	5/7096	10/18670	0.3178	0.5603	0.4177	B3GNT8/B3GNT2/B3GNT5/B4GALT5/B3GNT4	5
BP	GO:0032353	negative regulation of hormone biosynthetic process	5/7096	10/18670	0.3178	0.5603	0.4177	ATP1A1/NFKB1/BMP2/BMP5/CYP27B1	5
BP	GO:0033131	regulation of glucokinase activity	5/7096	10/18670	0.3178	0.5603	0.4177	COX11/DUSP12/PFKFB1/PFKFB2/BAD	5
BP	GO:0033690	positive regulation of osteoblast proliferation	5/7096	10/18670	0.3178	0.5603	0.4177	BMP2/ABL1/HPSE/CTHRC1/TMEM119	5
BP	GO:0034058	endosomal vesicle fusion	5/7096	10/18670	0.3178	0.5603	0.4177	SAMD9L/VPS41/SAMD9/SPHK1/VPS8	5
BP	GO:0034350	regulation of glial cell apoptotic process	5/7096	10/18670	0.3178	0.5603	0.4177	DLL1/PRKCD/CDK5/TRAF2/PRKCA	5
BP	GO:0035247	peptidyl-arginine omega-N-methylation	5/7096	10/18670	0.3178	0.5603	0.4177	PRMT9/NDUFAF7/PRMT5/CARM1/PRMT1	5
BP	GO:0035845	photoreceptor cell outer segment organization	5/7096	10/18670	0.3178	0.5603	0.4177	BBS4/NPHP4/IFT20/TOPORS/RP1	5
BP	GO:0035871	protein K11-linked deubiquitination	5/7096	10/18670	0.3178	0.5603	0.4177	TNFAIP3/USP30/YOD1/OTUD3/USP37	5
BP	GO:0042436	indole-containing compound catabolic process	5/7096	10/18670	0.3178	0.5603	0.4177	IDO1/KYNU/HAAO/IDO2/TDO2	5
BP	GO:0043471	regulation of cellular carbohydrate catabolic process	5/7096	10/18670	0.3178	0.5603	0.4177	PGAM1/PPP1R3D/PPP1R3B/PPP1CA/PPP1CB	5
BP	GO:0044539	long-chain fatty acid import	5/7096	10/18670	0.3178	0.5603	0.4177	SLC27A1/CD36/SLC27A2/FABP3/SPX	5
BP	GO:0044557	relaxation of smooth muscle	5/7096	10/18670	0.3178	0.5603	0.4177	SLC8A1/SOD1/RGS2/ADORA2B/KCNMA1	5
BP	GO:0044803	multi-organism membrane organization	5/7096	10/18670	0.3178	0.5603	0.4177	HYAL2/FCHSD1/CCR5/CD4/FCHSD2	5
BP	GO:0045348	positive regulation of MHC class II biosynthetic process	5/7096	10/18670	0.3178	0.5603	0.4177	AZU1/JAK2/TLR4/SIRT1/IFNG	5
BP	GO:0045713	low-density lipoprotein particle receptor biosynthetic process	5/7096	10/18670	0.3178	0.5603	0.4177	HNRNPK/FURIN/SCAP/SEC24A/CNPY2	5
BP	GO:0045988	negative regulation of striated muscle contraction	5/7096	10/18670	0.3178	0.5603	0.4177	KCNE3/SRI/PIK3CG/ATP1A2/BIN1	5
BP	GO:0046218	indolalkylamine catabolic process	5/7096	10/18670	0.3178	0.5603	0.4177	IDO1/KYNU/HAAO/IDO2/TDO2	5
BP	GO:0046322	negative regulation of fatty acid oxidation	5/7096	10/18670	0.3178	0.5603	0.4177	APPL2/SIRT4/ACACB/DGAT2/ACADVL	5
BP	GO:0046485	ether lipid metabolic process	5/7096	10/18670	0.3178	0.5603	0.4177	TMEM86A/AGPS/TMEM86B/FAR1/GNPAT	5
BP	GO:0048755	branching morphogenesis of a nerve	5/7096	10/18670	0.3178	0.5603	0.4177	BCL11A/LRRK2/SHOX2/MAP3K13/RTN4	5
BP	GO:0052646	alditol phosphate metabolic process	5/7096	10/18670	0.3178	0.5603	0.4177	GPAM/ABHD6/GK/GK5/ACP6	5
BP	GO:0060033	anatomical structure regression	5/7096	10/18670	0.3178	0.5603	0.4177	SPI1/SMAD5/NINJ1/BMPR1A/AMHR2	5
BP	GO:0061299	retina vasculature morphogenesis in camera-type eye	5/7096	10/18670	0.3178	0.5603	0.4177	LRP5/CYP1B1/NRP1/FZD4/LAMA1	5
BP	GO:0061635	regulation of protein complex stability	5/7096	10/18670	0.3178	0.5603	0.4177	ATG14/SQSTM1/TAPBP/NCLN/TRAPPC11	5
BP	GO:0070314	G1 to G0 transition	5/7096	10/18670	0.3178	0.5603	0.4177	EZH2/RAB11FIP4/CYP27B1/CAPN3/PHGDH	5
BP	GO:0071104	response to interleukin-9	5/7096	10/18670	0.3178	0.5603	0.4177	IL2RG/STAT3/STAT1/STAT5A/JAK1	5
BP	GO:0071313	cellular response to caffeine	5/7096	10/18670	0.3178	0.5603	0.4177	SLC8A1/RYR1/PPARGC1A/CASQ2/TMEM38B	5
BP	GO:0072531	pyrimidine-containing compound transmembrane transport	5/7096	10/18670	0.3178	0.5603	0.4177	SLC19A2/AQP9/SLC25A19/SLC28A3/SLC25A33	5
BP	GO:0075522	IRES-dependent viral translational initiation	5/7096	10/18670	0.3178	0.5603	0.4177	EIF2D/MCTS1/EIF3B/PCBP2/SSB	5
BP	GO:0097278	complement-dependent cytotoxicity	5/7096	10/18670	0.3178	0.5603	0.4177	CD55/CD59/CD5L/HSP90AB1/RAB27A	5
BP	GO:0098722	asymmetric stem cell division	5/7096	10/18670	0.3178	0.5603	0.4177	ARHGEF2/ETV5/SOX5/ZBTB16/FGF13	5
BP	GO:0098734	macromolecule depalmitoylation	5/7096	10/18670	0.3178	0.5603	0.4177	ABHD13/LYPLAL1/ABHD12/ABHD17C/LYPLA2	5
BP	GO:0098917	retrograde trans-synaptic signaling	5/7096	10/18670	0.3178	0.5603	0.4177	DAGLB/PLCB1/FABP5/SYT4/DAG1	5
BP	GO:0140052	cellular response to oxidised low-density lipoprotein particle stimulus	5/7096	10/18670	0.3178	0.5603	0.4177	MYD88/TICAM1/CD36/TLR4/TLR6	5
BP	GO:1900426	positive regulation of defense response to bacterium	5/7096	10/18670	0.3178	0.5603	0.4177	GRN/UNC13B/SIGLEC16/CYBA/HAVCR2	5
BP	GO:1901725	regulation of histone deacetylase activity	5/7096	10/18670	0.3178	0.5603	0.4177	PINK1/VEGFA/LRRK2/PRKD2/CAMK2D	5
BP	GO:1903789	regulation of amino acid transmembrane transport	5/7096	10/18670	0.3178	0.5603	0.4177	RGS2/PER2/ARL6IP1/PSEN1/ATP1A2	5
BP	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA	5/7096	10/18670	0.3178	0.5603	0.4177	TGFB1/BCDIN3D/NCOR1/ZMPSTE24/ZC3H10	5
BP	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA	5/7096	10/18670	0.3178	0.5603	0.4177	MAP2K1/TGFB1/BMP4/MAP2K2/EGFR	5
BP	GO:1904779	regulation of protein localization to centrosome	5/7096	10/18670	0.3178	0.5603	0.4177	NUP62/GSK3B/UBXN2B/NSFL1C/BICD1	5
BP	GO:1990535	neuron projection maintenance	5/7096	10/18670	0.3178	0.5603	0.4177	INSR/MAP1A/PSEN1/APP/ABCD1	5
BP	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin	5/7096	10/18670	0.3178	0.5603	0.4177	WNT5A/FLOT1/ADAM19/DENND6A/SERPINF2	5
BP	GO:2000271	positive regulation of fibroblast apoptotic process	5/7096	10/18670	0.3178	0.5603	0.4177	STK17B/BTG1/BCL2L11/STK17A/PRDM11	5
BP	GO:2000628	regulation of miRNA metabolic process	5/7096	10/18670	0.3178	0.5603	0.4177	NFKB1/RELA/HRAS/DROSHA/PNPT1	5
BP	GO:2001054	negative regulation of mesenchymal cell apoptotic process	5/7096	10/18670	0.3178	0.5603	0.4177	HIF1A/PAX8/BMP7/HNF1B/GDF5	5
BP	GO:0006909	phagocytosis	145/7096	369/18670	0.3214	0.5664	0.4223	SRPX/MYD88/MYO1G/ITGAM/FPR2/IL2RG/FYN/TLR2/ANXA1/CLEC7A/APPL2/LYN/ATG3/FCGR1A/SLC11A1/CDC42SE1/ICAM3/CSK/AZU1/SOD1/JMJD6/SYT11/HCK/RHOBTB1/LYAR/FCN1/MARCO/CAMK1D/CD93/SCARB1/PTPRC/IL15/P2RX7/TNF/RAB31/ACTR2/SLAMF1/ANXA3/AXL/ACTB/TGFB1/ARHGAP25/PAK1/CD36/LEP/ITGAL/NCF4/PRKCD/CORO1A/P2RY6/PTX3/NCF2/BAIAP2/TLR4/CDC42SE2/FGR/IL2RB/ABR/NCK1/CYFIP2/ABL1/ABCA1/IL1B/AIF1/SIRPB1/ARPC1A/PLCG2/LDLR/RAP1A/RAB20/CD300LF/LRP1/HMGB1/CEACAM4/CRK/TYROBP/SH3BP1/RAC1/TRBC1/ARPC1B/CYFIP1/MYO1C/BIN2/PTK2/BCR/MYH9/ARHGAP12/SPHK1/IL15RA/XKR8/WIPF2/DNM2/TGM2/CD247/CD47/UNC13D/NR1H3/RAB5A/ITGA2/CD3G/ELMO3/GRB2/CD300A/CYBA/RAB7B/CORO1C/ACTR3/CALR/ABCA7/ELMO1/IRF8/VAV1/PLD4/PLD2/MERTK/MAPK1/APOA1/EIF2AK1/SIRPG/TREM2/PLA2G6/ARPC4/MYO10/MEGF10/IFNG/HSP90AB1/FCGR2A/LBP/MYH2/WIPF1/ARPC2/PRTN3/TYRO3/MET/TM9SF4/TULP1/WAS/RHOBTB2/APPL1/RAB27A/NCKAP1/ELMO2/IGHD/PIK3CB/PTPRJ	145
BP	GO:0032515	negative regulation of phosphoprotein phosphatase activity	25/7096	60/18670	0.3229	0.5689	0.4241	PPP1R15A/MGAT5/TNF/GSK3B/CABIN1/PHACTR2/PHACTR1/PPP1R26/PPP1R14A/ELFN1/PPP1R37/PPP1R2/PPP1R14B/GNAI2/BOD1L1/ELFN2/PPP1R36/MYOZ1/PPP1R11/LMTK2/MASTL/PPP1R14D/SET/ROCK2/BOD1	25
BP	GO:0042445	hormone metabolic process	92/7096	232/18670	0.3241	0.5709	0.4256	VDR/HSD17B14/RBP1/POR/CYP27A1/ATP1A1/SRD5A1/AKR1B1/ALDH9A1/ECE1/SPP1/PLEKHA1/ACAA1/ALDH1A1/RDH10/YWHAH/SCARB1/RETSAT/EGR1/HFE/TNF/AKR1C3/NFKB1/DHRS3/DHRS9/CPQ/CYP1B1/HIF1A/SGPL1/LEP/RDH16/BMP2/AKR1C1/CYP2S1/PAX8/CTSZ/IL1B/FURIN/HSD11B1/PLB1/STARD3NL/HSD17B4/ATP6AP2/DGAT2/RDH12/PPARGC1A/GNB3/BACE2/CPA3/PCSK7/BMP5/CYP2D6/CYP1A2/CYP26B1/TIPARP/ALDH8A1/PCSK5/RDH5/SCPEP1/ZMPSTE24/ARNT/STUB1/AKR1B10/FDX1/ADH1B/PCSK6/SRD5A3/CMA1/HSD17B3/TCF7L2/APOA1/CYP27B1/IFNG/BCO2/CTSG/REN/DUOXA1/SULT1B1/CYP26A1/HPN/SCG5/CHAT/CRABP2/GHR/DIO2/CYP46A1/CACNA1H/ADH7/CYP2C8/RBP4/PNPLA4/HSD17B12	92
BP	GO:0042220	response to cocaine	23/7096	55/18670	0.3255	0.5732	0.4273	CRHBP/HNMT/UBE3A/PTK2B/MBD1/HSPA5/CDK5/HOMER1/HDAC2/DNM2/PITX3/FADD/DNMT3A/MDM2/CHRNB2/SMPD1/HSP90AB1/CCNA2/MTOR/HDAC5/SNCA/EFTUD2/HTR3A	23
BP	GO:0008652	cellular amino acid biosynthetic process	34/7096	83/18670	0.3265	0.5748	0.4285	ATP2B4/SEPHS2/ADI1/PSPH/MTR/ALDH18A1/APIP/NAGS/MTRR/DPYD/ENOPH1/GATM/ASNSD1/GLUD1/PLOD1/MTAP/SLC25A12/SHMT2/GLUD2/SERINC3/CTH/ASNS/BHMT/PLOD2/GAMT/GLS/GOT2/AGXT2/SHMT1/AASDHPPT/SRR/CAD/BCAT2/PHGDH	34
BP	GO:0001838	embryonic epithelial tube formation	50/7096	124/18670	0.3279	0.5752	0.4288	VASP/BCL10/SKI/WNT5A/TSC1/TCTN1/IFT172/DVL2/PRKACB/IFT57/ZEB2/PLXNB2/MIB1/TGFB1/TULP3/PFN1/HIF1A/TRAF6/FUZ/CASP3/ABL1/PAX8/SEMA4C/BMP7/IFT52/GLMN/BBS4/BMP5/BMP4/KDM2B/KIF20B/CFL1/PRKACA/SPINT1/MKS1/TEAD2/FZD1/DVL1/KAT2A/CTHRC1/HNF1B/RET/PHACTR4/IRX1/WNT6/FZD2/SOX4/GRHL3/PTCH1/GRHL2	50
BP	GO:0042692	muscle cell differentiation	151/7096	385/18670	0.3279	0.5752	0.4288	IGF1/MYOF/SLC8A1/TRIM32/DLL1/MAPK12/MEF2A/SKI/RBPJ/LMNA/TSC1/CAPN2/RGS2/SIK1/FLOT1/UCHL1/KLHL41/IL4R/CXCL9/MORF4L2/EZH2/AKAP13/SLC9A1/IFRD1/CXCL10/KRAS/TMOD3/CD53/TGFB1/NFATC3/CTNNA1/PAK1/CFL2/PLEKHO1/SRF/NRG1/CBY1/DYRK1B/RBM4/FLT3LG/RYR1/BMP2/PARP2/ACTC1/VEGFA/CASP3/ABL1/MYBPC3/SEMA4C/HEY1/EHD1/DMD/MED28/SIRT1/AFG3L2/HOMER1/CTDP1/PDGFB/CDK9/G6PD/MESP1/SMYD3/NLN/GLMN/MYH9/MIR34A/PDLIM5/PTGFRN/MYOG/PGM5/RXRA/CAPN9/TARBP2/BCL2/BMP4/TPM1/NFATC1/ANKRD17/ADAM12/CYP26B1/NFATC2/HDAC4/CTH/YY1/KLF5/OBSCN/KLHL40/FOXO4/KRT8/MAMSTR/MMP14/HES1/KDM6B/ZMPSTE24/CALR/CACYBP/MYOZ1/LMOD3/ALPK3/PPARA/CAV3/BIN3/ATP2A2/HEY2/MYOM2/EPC1/WNT1/KAT2A/HAMP/SHOX2/DNER/IFT20/SYPL2/MAP2K4/CASQ1/ITGA8/CAPN3/RORA/CASQ2/MEGF10/PRDM6/ASF1A/MAPK11/PIN1/RB1/FZD7/SYNPO2L/MSX1/GPX1/CSRP1/MTOR/HDAC5/ENG/PDCD4/P2RX2/CHUK/MYH3/FOXF1/TMEM119/WNT10B/GREM1/ACTA1/CACNA1H/SMO/BOC/WT1/KEL/BIN1/TNNT1/MEF2C/MYF6	151
BP	GO:0070588	calcium ion transmembrane transport	124/7096	315/18670	0.3279	0.5752	0.4288	SLC8A1/HTR2B/PKD2L1/FYN/PTPN6/ATP2B4/TMEM37/LYN/MCOLN1/TPCN1/DIAPH1/SLC25A25/ORAI2/CXCL9/YME1L1/CXCL11/PTPRC/P2RX7/SLC9A1/CXCL10/PKD2/CACNA2D3/TGFB1/KCNE3/ITPR1/PTK2B/MYO5A/PANX1/CORO1A/P2RY6/CATSPER1/MCU/AHNAK/RYR1/PDE4B/ABL1/STIM2/GSTO1/PLCG2/ATP2C1/P2RY12/DMD/TRPM4/AFG3L2/TRPM2/ORAI3/TMC2/LCK/G6PD/CCR5/SUMO1/PSEN2/SRI/RASA3/ANXA6/BAX/ATP1B1/CHRNA10/PRKACA/CYBA/MICU1/MCOLN2/F2R/GRIN2C/VDAC1/CAMK2D/PLCB1/CEMIP/ORAI1/CAV3/ATP2A2/ANXA2P2/LETM1/SLC8A2/STAC2/PSEN1/FMR1/GPR35/PARL/YWHAE/CASQ1/PLA2G6/SLC24A4/CAPN3/CASQ2/CACNG6/HRC/PKD1L2/MICU3/BDKRB1/EHD3/TMEM38B/LACRT/IL1RAPL1/PIK3CG/PMPCB/CACNB3/REM2/OPRL1/ANXA2/LIME1/TRPV4/SNCA/CX3CL1/SLC24A2/CCL19/SLN/TRPC4AP/CHERP/TMC1/KCNE2/ATP1A2/CCR7/SLC8A3/MCOLN3/CACNA2D4/FAM155A/CACNA1H/CACNA1F/TRPV3/BIN1/TRPV2/NTSR1/MICU2	124
BP	GO:0032873	negative regulation of stress-activated MAPK cascade	21/7096	50/18670	0.328	0.5752	0.4288	EZR/DUSP1/PINK1/DUSP10/MYC/GSTP1/DUSP3/TAOK3/PTPN22/PAFAH1B1/DUSP19/CYLD/NCOR1/ZMYND11/AMBP/IGBP1/HIPK3/DNAJA1/MEN1/PDCD4/AIDA	21
BP	GO:0070303	negative regulation of stress-activated protein kinase signaling cascade	21/7096	50/18670	0.328	0.5752	0.4288	EZR/DUSP1/PINK1/DUSP10/MYC/GSTP1/DUSP3/TAOK3/PTPN22/PAFAH1B1/DUSP19/CYLD/NCOR1/ZMYND11/AMBP/IGBP1/HIPK3/DNAJA1/MEN1/PDCD4/AIDA	21
BP	GO:0070741	response to interleukin-6	21/7096	50/18670	0.328	0.5752	0.4288	SPI1/SOCS3/SBNO2/STAT3/PTPN2/STAT1/JAK2/NFKB1/RELA/CEBPA/IL6ST/CHI3L1/IL6/PPARGC1A/SELPLG/FER/HAMP/PID1/ST18/JAK1/FGF23	21
BP	GO:0021915	neural tube development	64/7096	160/18670	0.3283	0.5752	0.4288	VASP/BCL10/SKI/WNT5A/TSC1/TCTN1/ZNF358/DCHS1/IFT172/DVL2/PRKACB/PKD2/IFT57/ZEB2/PLXNB2/MIB1/TGFB1/TULP3/PFN1/HIF1A/ARL13B/TRAF6/FUZ/CASP3/ABL1/SEMA4C/WDR19/INTU/ATP6AP2/GORAB/BMP7/IFT52/GLMN/BBS4/BMP5/BMP4/KDM2B/KIF20B/CFL1/PRKACA/SPINT1/MKS1/TEAD2/HES1/FZD1/DVL1/WNT1/KAT2A/PSEN1/CTHRC1/GPR161/PHACTR4/PLXNA2/TRAF3IP1/PAX7/FZD2/SOX4/GRHL3/TMEM107/PHGDH/SMO/PTCH1/C2CD3/GRHL2	64
BP	GO:0007599	hemostasis	134/7096	341/18670	0.3293	0.5752	0.4288	SH2B2/SERPINA1/SERPINB2/FYN/F5/PTPN6/PRKAR2B/CLIC1/MYL12A/LYN/IRF1/PROS1/DGKA/PLSCR1/PROCR/TFPI/HPS4/GNB1/FLNA/CD40/GNA15/PAFAH2/JAK2/CBX5/NFE2/VCL/P2RX7/A2M/CD59/PRKACB/SLC7A11/APOE/AK3/MICAL1/ENTPD1/LCP2/AXL/ACTB/DOCK8/TLN1/STXBP1/ITPR1/DGKD/ARRB1/GNAQ/HSPB1/CD36/CAPZA2/PRKCD/SRF/HBB/TSPAN32/TLR4/RAD51B/FIBP/RAP2B/DTNBP1/PLCG2/CAPZA1/TREML1/PIK3R6/P2RY12/EHD1/THBD/RAF1/GPI/RAC1/SERPING1/IL6/LCK/PDGFB/PLAUR/GNG2/MYH9/HPSE/HDAC2/P2RX1/VKORC1/MAFG/BLOC1S3/SERPINE1/PAPSS2/PRKACA/TEC/RAB5A/ITGA2/LMAN1/PLEK/PDGFA/IRF2/VWF/DMTN/F2R/BLOC1S4/NFE2L2/GGCX/C1QBP/VAV1/AP3B1/DOCK11/ANXA2P2/MERTK/MAPK1/GNA13/PHF21A/SLC4A1/DGKG/HPS6/HRG/CD34/EHD3/PIK3CG/F3/STXBP3/CSRP1/ANXA2/PRTN3/PRKCQ/TYRO3/HMG20B/ENPP4/P2RX2/TSPAN8/WAS/HBE1/PRKCA/RAB27A/SERPINF2/F9/GNA11/P2RY1/AVPR2/PIK3CB/P2RX5	134
BP	GO:0000098	sulfur amino acid catabolic process	7/7096	15/18670	0.3296	0.5752	0.4288	PCYOX1/MTRR/PCYOX1L/TST/MPST/CTH/MAT1A	7
BP	GO:0007039	protein catabolic process in the vacuole	7/7096	15/18670	0.3296	0.5752	0.4288	LAMP2/TCIRG1/LDLR/LRP1/MGAT3/LAPTM4B/CPA2	7
BP	GO:0009415	response to water	7/7096	15/18670	0.3296	0.5752	0.4288	PKD2L1/ATP2B4/AKR1B1/LRP11/PKD2/KRT8/COL18A1	7
BP	GO:0014856	skeletal muscle cell proliferation	7/7096	15/18670	0.3296	0.5752	0.4288	STAT3/PPARD/JAK2/PAXBP1/MYOG/MEGF10/EPHB1	7
BP	GO:0030299	intestinal cholesterol absorption	7/7096	15/18670	0.3296	0.5752	0.4288	LIMA1/CD36/LEP/AKR1C1/LDLR/APOA5/APOA1	7
BP	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	7/7096	15/18670	0.3296	0.5752	0.4288	PMAIP1/EEF1E1/ATM/SPRED1/ATR/MSX1/HIC1	7
BP	GO:0043650	dicarboxylic acid biosynthetic process	7/7096	15/18670	0.3296	0.5752	0.4288	GLUD1/KYNU/HAAO/SLC25A12/GLUD2/GLS/GOT2	7
BP	GO:0045360	regulation of interleukin-1 biosynthetic process	7/7096	15/18670	0.3296	0.5752	0.4288	AZU1/JAK2/EGR1/AGER/TYROBP/IFNG/APP	7
BP	GO:0046321	positive regulation of fatty acid oxidation	7/7096	15/18670	0.3296	0.5752	0.4288	IRS2/PPARGC1A/MLYCD/CPT1A/PPARA/NR4A3/ABCD1	7
BP	GO:0051299	centrosome separation	7/7096	15/18670	0.3296	0.5752	0.4288	NUP62/KIF3B/UBXN2B/NSFL1C/NDEL1/AURKA/CEP85	7
BP	GO:0055089	fatty acid homeostasis	7/7096	15/18670	0.3296	0.5752	0.4288	APOE/SIRT1/DGAT2/PRKAA1/POLD1/ABCD1/NR1H4	7
BP	GO:0060099	regulation of phagocytosis, engulfment	7/7096	15/18670	0.3296	0.5752	0.4288	APPL2/RAB31/CD36/ITGA2/CD300A/ABCA7/TREM2	7
BP	GO:0070365	hepatocyte differentiation	7/7096	15/18670	0.3296	0.5752	0.4288	ANXA1/PCK2/MESP1/ITGA2/WNT1/HNF1B/E2F8	7
BP	GO:0090177	establishment of planar polarity involved in neural tube closure	7/7096	15/18670	0.3296	0.5752	0.4288	WNT5A/DVL2/FZD1/DVL1/CTHRC1/FZD2/GRHL3	7
BP	GO:0090192	regulation of glomerulus development	7/7096	15/18670	0.3296	0.5752	0.4288	EGR1/BMP7/PDGFB/BMP4/RET/WT1/PDGFD	7
BP	GO:0090197	positive regulation of chemokine secretion	7/7096	15/18670	0.3296	0.5752	0.4288	MBP/IL4R/TNF/AIF1/LRP1/ALOX15B/CSF1R	7
BP	GO:0098719	sodium ion import across plasma membrane	7/7096	15/18670	0.3296	0.5752	0.4288	SLC8A1/SLC9A9/SLC9A1/TRPM4/SLC9A7/HCN4/SLC9C2	7
BP	GO:0099558	maintenance of synapse structure	7/7096	15/18670	0.3296	0.5752	0.4288	ARF6/CTBP2/OPHN1/CHCHD10/SYNGAP1/C1QL1/RAB3A	7
BP	GO:1903350	response to dopamine	7/7096	15/18670	0.3296	0.5752	0.4288	ATF4/SIN3A/ABL1/LRRK2/HDAC2/DNM2/MAPK1	7
BP	GO:1903543	positive regulation of exosomal secretion	7/7096	15/18670	0.3296	0.5752	0.4288	STAM/SDCBP/CHMP2A/TSG101/HGS/VPS4B/IFNG	7
BP	GO:1904874	positive regulation of telomerase RNA localization to Cajal body	7/7096	15/18670	0.3296	0.5752	0.4288	RUVBL2/RUVBL1/NAF1/NHP2/CCT4/CCT8/NOP10	7
BP	GO:2001256	regulation of store-operated calcium entry	7/7096	15/18670	0.3296	0.5752	0.4288	SARAF/HOMER3/HOMER1/SPINK1/CASQ1/CD84/EFHB	7
BP	GO:0008306	associative learning	32/7096	78/18670	0.3298	0.5752	0.4288	NRGN/FOS/LGMN/SLC7A11/KRAS/HMGCR/BTG2/ACTR2/CLN8/HIF1A/SRF/CDK5/CLN3/CREB1/NPTN/ADCY3/RGS14/SYNGAP1/SHANK1/MAP1A/CHRNB2/IFT20/RIN1/DBH/OPRL1/RELN/MTOR/BRSK1/APP/ATP1A2/CTNS/SYNPO	32
BP	GO:0042246	tissue regeneration	32/7096	78/18670	0.3298	0.5752	0.4288	IGF1/ANXA1/CDKN1A/PPARD/DUSP10/EZH2/IFRD1/PKM/CPQ/ADAM15/NINJ1/FZD9/APOA5/PTGFRN/MYOG/NINJ2/TARBP2/CDKN1B/TEC/KLF5/MYOZ1/BIN3/CAPN3/FZD7/LGR6/GPX1/DAG1/PAX7/WNT7A/WNT10B/GJA1/MYF6	32
BP	GO:0072347	response to anesthetic	32/7096	78/18670	0.3298	0.5752	0.4288	CRHBP/PEA15/ATG7/FOSB/HNMT/RELA/UBE3A/MAP1LC3A/PTK2B/MBD1/HSPA5/CDK5/AIF1/HOMER1/HDAC2/DNM2/PITX3/GOT2/ADA/FADD/DNMT3A/MDM2/CHRNB2/SRR/SMPD1/HSP90AB1/CCNA2/MTOR/HDAC5/SNCA/EFTUD2/HTR3A	32
BP	GO:0000018	regulation of DNA recombination	41/7096	101/18670	0.3298	0.5752	0.4288	USP51/IL27RA/MAD2L2/STAT6/RAD51AP1/BCL6/CD40/PTPRC/KLHL15/MAGEF1/ALYREF/ACTR2/PPP4C/IL7R/PPP4R2/TGFB1/RMI2/SMCHD1/SMARCAD1/MLH1/PARP3/FUS/CLCF1/TIMELESS/TFRC/TNFSF4/RTEL1/KPNA1/ERCC2/EXOSC3/TEX15/TBX21/APLF/EXOSC6/WAS/PAXIP1/ATAD5/UBE2B/SPIDR/ZRANB3/FIGNL1	41
BP	GO:0001974	blood vessel remodeling	19/7096	45/18670	0.3304	0.576	0.4294	EPAS1/CCR2/ACVR2B/RBPJ/CST3/AXL/TGFB1/ABR/BCR/TGM2/BAX/MDM2/ATP7A/HRG/DBH/BAK1/HOXA3/MEF2C/BMPR2	19
BP	GO:0051985	negative regulation of chromosome segregation	19/7096	45/18670	0.3304	0.576	0.4294	DUSP1/MAD2L2/DYNC1LI1/SPDL1/NAA10/KLHL22/CDK5RAP2/ESPL1/ZNF207/LCMT1/ATM/BUB3/NDC80/GEN1/ZW10/MOS/CDC20/PCID2/IK	19
BP	GO:0007173	epidermal growth factor receptor signaling pathway	48/7096	119/18670	0.3314	0.5775	0.4305	STAM/RHBDF2/PTPN2/ARAP1/NUP62/FBXW7/GAB1/DUSP3/TGFB1/DGKD/CBLB/SOCS5/ARF4/ZFYVE28/PTK2B/ZGPAT/NCF1/ABL1/PTK6/SHC1/SHKBP1/PDE6G/PLAUR/RNF115/DOK1/PTK2/KIF16B/SNX6/MMP9/RNF126/TSG101/HGS/GRB2/GRB7/FER/SPRY1/VPS25/EGFR/ADAM17/SPRY2/PSEN1/SNX5/HBEGF/APP/SHC3/SLC30A10/PTPRJ/RHBDF1	48
BP	GO:0007596	blood coagulation	132/7096	336/18670	0.3322	0.5775	0.4305	SH2B2/SERPINA1/SERPINB2/FYN/F5/PTPN6/PRKAR2B/CLIC1/MYL12A/LYN/IRF1/PROS1/DGKA/PLSCR1/PROCR/TFPI/HPS4/GNB1/FLNA/CD40/GNA15/PAFAH2/JAK2/CBX5/NFE2/VCL/P2RX7/A2M/CD59/PRKACB/SLC7A11/APOE/AK3/MICAL1/ENTPD1/LCP2/AXL/ACTB/DOCK8/TLN1/STXBP1/ITPR1/DGKD/ARRB1/GNAQ/HSPB1/CD36/CAPZA2/PRKCD/SRF/HBB/TSPAN32/TLR4/RAD51B/FIBP/RAP2B/DTNBP1/PLCG2/CAPZA1/TREML1/PIK3R6/P2RY12/EHD1/THBD/RAF1/RAC1/SERPING1/IL6/LCK/PDGFB/PLAUR/GNG2/MYH9/HPSE/HDAC2/P2RX1/VKORC1/MAFG/BLOC1S3/SERPINE1/PAPSS2/PRKACA/TEC/RAB5A/ITGA2/LMAN1/PLEK/PDGFA/IRF2/VWF/DMTN/F2R/BLOC1S4/NFE2L2/GGCX/C1QBP/VAV1/AP3B1/DOCK11/ANXA2P2/MERTK/MAPK1/GNA13/PHF21A/SLC4A1/DGKG/HPS6/HRG/CD34/EHD3/PIK3CG/F3/STXBP3/CSRP1/ANXA2/PRTN3/PRKCQ/TYRO3/HMG20B/ENPP4/P2RX2/TSPAN8/WAS/HBE1/PRKCA/RAB27A/SERPINF2/F9/GNA11/P2RY1/PIK3CB/P2RX5	132
BP	GO:0032008	positive regulation of TOR signaling	17/7096	40/18670	0.3325	0.5775	0.4305	WDR24/SEH1L/LEP/KLHL22/LAMTOR1/RRAGD/MLST8/FLCN/LAMTOR4/RRAGA/LAMTOR5/TELO2/SMCR8/TREM2/CLEC16A/RELN/SLC38A9	17
BP	GO:0042036	negative regulation of cytokine biosynthetic process	17/7096	40/18670	0.3325	0.5775	0.4305	KLF4/ZFP36/NLRP12/PTPRC/NFKB1/LILRB1/NMI/TYROBP/IL6/TRIB2/LAG3/INHBA/SIGIRR/INHA/MAP2K5/ASB1/GHRL	17
BP	GO:0061462	protein localization to lysosome	17/7096	40/18670	0.3325	0.5775	0.4305	NCOA4/LAMP2/M6PR/SH3BP4/NAGPA/GNPTAB/CLU/KPTN/LAMTOR4/NEDD4/HGS/LAMTOR5/AP3B1/AP3M1/RTN4/SNX16/ROCK2	17
BP	GO:0090184	positive regulation of kidney development	17/7096	40/18670	0.3325	0.5775	0.4305	LGR4/MYC/EGR1/MAGED1/TGFB1/VEGFA/PAX8/BASP1/PDGFB/BMP4/PDGFA/RET/WNT2B/SMO/CD24/WT1/PDGFD	17
BP	GO:0090207	regulation of triglyceride metabolic process	17/7096	40/18670	0.3325	0.5775	0.4305	SLC27A1/PANK2/FBXW7/SIK1/ATG14/SCARB1/APOE/NR1H2/LDLR/LMF1/DGAT2/GNB3/APOA5/NR1H3/SERPINA12/PIK3CG/THRSP	17
BP	GO:1905819	negative regulation of chromosome separation	17/7096	40/18670	0.3325	0.5775	0.4305	DUSP1/MAD2L2/DYNC1LI1/SPDL1/KLHL22/CDK5RAP2/ZNF207/LCMT1/ATM/BUB3/NDC80/GEN1/ZW10/MOS/CDC20/PCID2/IK	17
BP	GO:0042632	cholesterol homeostasis	39/7096	96/18670	0.3333	0.5775	0.4305	FABP4/NPC2/SCARB1/SOAT1/CETP/APOE/LRP5/LIMA1/NR1H2/AKR1C1/ABCA1/LAMTOR1/LDLR/EHD1/SIRT1/DGAT2/FABP3/TMEM97/APOA5/MIR34A/MED13/LCAT/ABCG1/NR1H3/RALY/SREBF2/NFE2L1/INSIG1/MALL/IL18/CAV3/NUS1/COMMD9/APOA1/RORA/SEC24A/NR1H4/CD24/G6PC	39
BP	GO:0055001	muscle cell development	74/7096	186/18670	0.3333	0.5775	0.4305	IGF1/MYOF/SLC8A1/MEF2A/SKI/LMNA/RGS2/UCHL1/KLHL41/AKAP13/TMOD3/PAK1/CFL2/SRF/RYR1/PARP2/ACTC1/VEGFA/MYBPC3/DMD/AFG3L2/HOMER1/CTDP1/G6PD/SMYD3/PDLIM5/MYOG/PGM5/CAPN9/BCL2/BMP4/TPM1/NFATC2/HDAC4/YY1/OBSCN/KLHL40/KRT8/HES1/ZMPSTE24/MYOZ1/LMOD3/ALPK3/PPARA/CAV3/BIN3/ATP2A2/HEY2/MYOM2/HAMP/SHOX2/DNER/SYPL2/MAP2K4/CASQ1/CAPN3/CASQ2/MEGF10/PIN1/SYNPO2L/GPX1/CSRP1/MTOR/ENG/P2RX2/MYH3/WNT10B/ACTA1/SMO/KEL/BIN1/TNNT1/MEF2C/MYF6	74
BP	GO:0002374	cytokine secretion involved in immune response	9/7096	20/18670	0.3343	0.5775	0.4305	NOD2/TLR2/WNT5A/TNFRSF14/NLRP3/TNF/LILRB1/APOA1/TRIM6	9
BP	GO:0006271	DNA strand elongation involved in DNA replication	9/7096	20/18670	0.3343	0.5775	0.4305	GINS1/POLD2/RFC3/RNASEH1/PCNA/GINS4/POLA1/LIG3/FEN1	9
BP	GO:0007549	dosage compensation	9/7096	20/18670	0.3343	0.5775	0.4305	EIF1/METTL3/YTHDC1/PCGF3/SMCHD1/CDYL/BRCA1/RLIM/UPF1	9
BP	GO:0008356	asymmetric cell division	9/7096	20/18670	0.3343	0.5775	0.4305	ACTR2/ARHGEF2/ETV5/ASPM/RGS14/ACTR3/SOX5/ZBTB16/FGF13	9
BP	GO:0010042	response to manganese ion	9/7096	20/18670	0.3343	0.5775	0.4305	PTGS2/ATF4/HSPA5/EIF2S1/LRRK2/ADAM9/ATP7A/APP/SLC30A10	9
BP	GO:0032211	negative regulation of telomere maintenance via telomerase	9/7096	20/18670	0.3343	0.5775	0.4305	HNRNPA1/DCP2/NAT10/HNRNPC/XRN1/ACD/CTC1/GNL3L/POT1	9
BP	GO:0043691	reverse cholesterol transport	9/7096	20/18670	0.3343	0.5775	0.4305	SCARB1/CETP/APOE/ABCA1/CLU/ABCA5/LCAT/ABCG1/APOA1	9
BP	GO:0046823	negative regulation of nucleocytoplasmic transport	9/7096	20/18670	0.3343	0.5775	0.4305	BARD1/CHP1/RAB23/CD36/CDK5/SP100/MDFIC/TXN/PKIA	9
BP	GO:0051580	regulation of neurotransmitter uptake	9/7096	20/18670	0.3343	0.5775	0.4305	RGS2/FLOT1/PER2/ARL6IP1/TOR1A/PSEN1/RAB3B/SNCA/ATP1A2	9
BP	GO:0090195	chemokine secretion	9/7096	20/18670	0.3343	0.5775	0.4305	MBP/IL4R/TNF/AIF1/LRP1/ALOX15B/MCOLN2/CSF1R/FOXP1	9
BP	GO:0097062	dendritic spine maintenance	9/7096	20/18670	0.3343	0.5775	0.4305	FYN/APOE/INSR/IGF1R/HOMER1/MTMR2/ITGA3/PICK1/ZMYND8	9
BP	GO:0097503	sialylation	9/7096	20/18670	0.3343	0.5775	0.4305	ST6GALNAC4/ST3GAL2/ST8SIA4/ST6GALNAC5/ST3GAL1/ST6GALNAC3/ST6GALNAC6/ST8SIA1/ST3GAL5	9
BP	GO:1900151	regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	9/7096	20/18670	0.3343	0.5775	0.4305	ZFP36/TOB1/AGO2/BTG2/TNRC6B/TNRC6A/CPEB3/CNOT7/ZFP36L2	9
BP	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	15/7096	35/18670	0.3343	0.5775	0.4305	TSR1/WDR46/KRI1/ABT1/RPS21/RPS19/RCL1/DCAF13/NOL10/RPS16/FAM207A/TSR2/MRPS9/UTP3/RRS1	15
BP	GO:0070873	regulation of glycogen metabolic process	15/7096	35/18670	0.3343	0.5775	0.4305	IGF1/GSK3B/DYRK2/PPP1R3E/INSR/PPP1R3D/IRS2/KHK/INPP5K/PPP1R3B/PPP1R3F/PPP1CA/PPP1CB/ESRRB/MTOR	15
BP	GO:0071108	protein K48-linked deubiquitination	15/7096	35/18670	0.3343	0.5775	0.4305	TNFAIP3/USP9X/CYLD/OTUD4/OTUD5/DESI2/USP27X/ATXN3/YOD1/USP7/UBXN1/OTUD3/BAP1/USP19/USP37	15
BP	GO:0051346	negative regulation of hydrolase activity	182/7096	466/18670	0.3348	0.5775	0.4305	KLF4/SERPINA1/RARRES1/SERPINB2/ANXA1/SERPINB9/CDKN2D/CST6/POR/CDC42SE1/TSC1/PROS1/TMBIM6/PTGS2/PPP1R15A/GAPDH/TIMP2/CHP1/TFPI/SH3RF1/MGAT5/RPS6KA3/LXN/BIRC2/UBE2Z/RGS2/CD44/WDR81/MCM2/F11R/APOC1/PZP/LAMP3/A2M/TNF/PEBP1/IQGAP2/GSK3B/VCPKMT/CST3/MICAL1/CABIN1/SH3BP4/RDX/PHACTR2/HGF/ARL6IP1/ARRB1/PHACTR1/MAPK7/PPP1R26/CAST/SERPINB1/PTX3/SPOCD1/ARFGEF1/PPP1R14A/ELFN1/PPP1R37/VEGFA/PPP1R2/EGLN1/RENBP/SFN/HRAS/ABL1/SFI1/PPP1R14B/SERPINB8/PAK2/DFFA/FURIN/GZMA/CPAMD8/CNST/SEMA4D/WFDC12/RAF1/SIRT1/MKKS/UCHL5/GPSM1/SERPING1/LRRK2/PLAUR/CR1/SPINK1/PDE6D/CD2BP2/DNAJB6/TIMP4/SERPINA9/DDX3X/BICD1/WFDC1/CST7/BBS4/FNIP1/LMTK3/ZFYVE1/MMP9/GNAI2/BOD1L1/SERPINE1/BCAS3/ELFN2/COL7A1/TIMP1/BIRC3/OXA1L/SPINT1/CSTA/SPOCK2/PPP1R36/RFFL/IFIT1/PTPRN2/AMBP/BIRC7/SPRY1/ZCCHC9/RHOH/LAMTOR5/CAAP1/SERPINI2/MYOZ1/SPRED1/SERPINA12/GMIP/PPP1R11/RCC2/WFIKKN1/SLIT2/SPRY2/MDM2/APOA1/YWHAE/COL4A3/SYTL2/SERPINA7/IGBP1/UBXN1/LMTK2/SPOCK1/PXK/HRG/CRIM1/SERPINB4/MASTL/COL6A3/A2ML1/PCID2/SPINT3/PPP1R14D/MAP2K5/SPINK6/SET/SERPINB6/GPX1/PRKCZ/GPS1/PI3/TRIAP1/APP/SNCA/SERPINB10/XIAP/SNX16/PICALM/ROCK2/CCDC8/SERPINF2/BIN1/BOD1/ITIH3/SIAH2/APCS/CPEB2/FZD10/CD109/GCHFR/AIP	182
BP	GO:0000002	mitochondrial genome maintenance	13/7096	30/18670	0.3355	0.5775	0.4305	TYMP/ATG7/MEF2A/MPV17/SSBP1/PPARGC1A/FLCN/POLG/SLC25A33/RRM2B/LIG3/MSTO1/SESN2	13
BP	GO:0000305	response to oxygen radical	13/7096	30/18670	0.3355	0.5775	0.4305	NQO1/GCH1/SOD1/TNF/ERCC6/CD36/PRDX1/ADPRHL2/BMP7/NFE2L2/DHFR/ATP7A/MPO	13
BP	GO:0010586	miRNA metabolic process	13/7096	30/18670	0.3355	0.5775	0.4305	AGO2/NFKB1/RAN/RELA/SND1/BCDIN3D/HRAS/DICER1/TARBP2/AGO1/DIS3L2/DROSHA/PNPT1	13
BP	GO:0010743	regulation of macrophage derived foam cell differentiation	13/7096	30/18670	0.3355	0.5775	0.4305	NFKBIA/CETP/NFKB1/CD36/NR1H2/ABCA1/ABCA5/ALOX15B/ABCG1/NR1H3/IL18/PPARA/MAPK9	13
BP	GO:0042759	long-chain fatty acid biosynthetic process	13/7096	30/18670	0.3355	0.5775	0.4305	ALOX5/PTGS2/ACOT7/HPGD/MYO5A/GPX4/ALOX15B/CYP2D6/CYP1A2/GSTM4/ELOVL6/PLP1/CYP2C8	13
BP	GO:0044818	mitotic G2/M transition checkpoint	13/7096	30/18670	0.3355	0.5775	0.4305	HUS1B/TAOK3/ZNF830/SYF2/DONSON/ATM/RAD17/FOXO4/TICRR/BRCA1/CLSPN/TOPBP1/BRSK1	13
BP	GO:0045939	negative regulation of steroid metabolic process	13/7096	30/18670	0.3355	0.5775	0.4305	SOD1/ATP1A1/NFKB1/APOE/ERLIN1/BMP2/ERLIN2/BMP5/SCAP/INSIG1/CYP27B1/SNAI1/NR1H4	13
BP	GO:0045940	positive regulation of steroid metabolic process	13/7096	30/18670	0.3355	0.5775	0.4305	POR/STARD4/APOC1/TNF/APOE/IL1B/PPARGC1A/FGF1/APOA5/ABCG1/PRKAA1/APOA1/IFNG	13
BP	GO:0048384	retinoic acid receptor signaling pathway	13/7096	30/18670	0.3355	0.5775	0.4305	ACTN4/CTBP2/EZH2/AKR1C3/TRIM16/DHRS3/PML/CREM/RXRA/CYP26B1/CALR/CYP26A1/CRABP2	13
BP	GO:0071480	cellular response to gamma radiation	13/7096	30/18670	0.3355	0.5775	0.4305	CDKN1A/EGR1/TMEM109/HSPA5/HRAS/XRCC5/ATM/TSPYL5/CYBA/ZMPSTE24/ATR/MDM2/XRCC6	13
BP	GO:1905606	regulation of presynapse assembly	13/7096	30/18670	0.3355	0.5775	0.4305	ARF6/IL1RAP/MDGA1/NTNG2/FZD1/CBLN1/EIF4G1/IL1RAPL1/GPC4/APP/SNCA/WNT7A/CLSTN3	13
BP	GO:0002053	positive regulation of mesenchymal cell proliferation	11/7096	25/18670	0.3357	0.5775	0.4305	WNT5A/STAT1/MYC/LRP5/VEGFA/IRS2/BMPR1A/PDGFA/SHOX2/FOXF1/SMO	11
BP	GO:0002068	glandular epithelial cell development	11/7096	25/18670	0.3357	0.5775	0.4305	DLL1/WNT5A/GSK3B/RFX3/BMP5/BMP4/CLOCK/BAD/ARNTL/SIDT2/SMO	11
BP	GO:0003071	renal system process involved in regulation of systemic arterial blood pressure	11/7096	25/18670	0.3357	0.5775	0.4305	PTPRO/PDGFB/EMP2/PCSK5/CYBA/F2R/SUCNR1/REN/RHOA/GJA1/SERPINF2	11
BP	GO:0006688	glycosphingolipid biosynthetic process	11/7096	25/18670	0.3357	0.5775	0.4305	B4GALT6/B4GALNT1/B4GALT5/UGCG/ST8SIA4/ST6GALNAC5/PRKAA1/ST6GALNAC3/ST6GALNAC6/ST8SIA1/ST3GAL5	11
BP	GO:0019054	modulation by virus of host process	11/7096	25/18670	0.3357	0.5775	0.4305	ATG7/KPNA4/CASP8/BCL2L11/CCL8/CCNK/KPNA1/BAD/CD4/EIF2AK4/KPNB1	11
BP	GO:0019430	removal of superoxide radicals	11/7096	25/18670	0.3357	0.5775	0.4305	NQO1/GCH1/SOD1/TNF/CD36/PRDX1/BMP7/NFE2L2/DHFR/ATP7A/MPO	11
BP	GO:0032461	positive regulation of protein oligomerization	11/7096	25/18670	0.3357	0.5775	0.4305	BMF/PMAIP1/RHOC/AIM2/CLU/BCL2L11/BAX/MMP3/MMP1/SH3GLB1/SNX9	11
BP	GO:0045332	phospholipid translocation	11/7096	25/18670	0.3357	0.5775	0.4305	KCNN4/ATP8B2/ATP8A1/ATP11B/ATP10A/ABCA1/ATP8B1/ABCB4/ABCA7/TMEM30A/ATP10B	11
BP	GO:0045662	negative regulation of myoblast differentiation	11/7096	25/18670	0.3357	0.5775	0.4305	DLL1/PPARD/TNF/CXCL10/TGFB1/SRA1/MBNL3/BMP4/NMRK2/IL18/CMTM5	11
BP	GO:0071378	cellular response to growth hormone stimulus	11/7096	25/18670	0.3357	0.5775	0.4305	LYN/STAT6/STAT3/JAK2/STAT5A/MBD5/PTK2/PXN/GHR/SOCS2/GHRL	11
BP	GO:1904385	cellular response to angiotensin	11/7096	25/18670	0.3357	0.5775	0.4305	NFKB1/RELA/PRKCD/AGTRAP/ARID1B/CYBA/CAMK2A/NFE2L2/AHCYL1/SLC30A10/ROCK2	11
BP	GO:2000311	regulation of AMPA receptor activity	11/7096	25/18670	0.3357	0.5775	0.4305	CNIH3/ARC/SHISA9/ADRB2/SHANK1/RELN/GSG1L/SHISA8/NLGN2/SHANK3/MEF2C	11
BP	GO:0071242	cellular response to ammonium ion	28/7096	68/18670	0.3365	0.5787	0.4314	CRHBP/ATP2B4/ATG7/DIAPH1/GNB1/GNA15/CASP6/ATF4/SIN3A/PTAFR/GNAQ/CASP3/ABL1/AIF1/CASP7/LRRK2/HDAC2/DNM2/GNAI2/HNRNPD/CHRM2/CHRNA4/PLCB1/MAPK1/CHRNB2/CCNA2/ROCK2/GNA11	28
BP	GO:0060606	tube closure	37/7096	91/18670	0.3369	0.5792	0.4318	VASP/BCL10/SKI/WNT5A/TSC1/IFT172/DVL2/PRKACB/IFT57/ZEB2/PLXNB2/TGFB1/TULP3/PFN1/TRAF6/FUZ/CASP3/ABL1/SEMA4C/GLMN/BBS4/BMP4/KDM2B/KIF20B/PRKACA/SPINT1/MKS1/TEAD2/FZD1/DVL1/KAT2A/CTHRC1/PHACTR4/FZD2/GRHL3/PTCH1/GRHL2	37
BP	GO:0006493	protein O-linked glycosylation	44/7096	109/18670	0.3386	0.5818	0.4338	TMTC3/PGM3/B3GNT8/VEGFB/POMGNT2/LFNG/GALNT14/IL15/TET2/B3GNT2/POGLUT1/B3GNT5/TRAK2/ST6GALNAC4/ST3GAL2/GALNT7/MUC2/FKRP/SDF2L1/DPM1/GALNT6/TMTC2/GCNT1/GALNT12/MUC1/GALNT10/B4GALT5/MGAT5B/POMT1/SLC35C1/GALNT9/XXYLT1/POMT2/DPM3/B3GNT4/ST3GAL1/MUC6/OGT/TRAK1/MUCL1/C1GALT1/GALNT1/TET1/GALNT15	44
BP	GO:0051149	positive regulation of muscle cell differentiation	44/7096	109/18670	0.3386	0.5818	0.4338	IGF1/TRIM32/MAPK12/MEF2A/RBPJ/CAPN2/FLOT1/IL4R/CXCL9/MORF4L2/CD53/TGFB1/CTNNA1/NRG1/RBM4/FLT3LG/PARP2/ABL1/EHD1/SIRT1/MESP1/MIR34A/MYOG/TARBP2/BCL2/BMP4/CYP26B1/NFATC2/CTH/MAMSTR/MMP14/LMOD3/CAV3/KAT2A/HAMP/SHOX2/MAPK11/PIN1/MTOR/ENG/GREM1/BOC/MEF2C/MYF6	44
BP	GO:0034394	protein localization to cell surface	26/7096	63/18670	0.34	0.5838	0.4353	ARF6/KCNAB2/LRIG2/FCN1/GGA2/FLNA/VCL/HFE/TNF/PIGK/GOPC/TYROBP/SNX33/USP4/TOR1A/EMP2/CD247/RANGRF/ABCA7/COMMD1/CAV3/MAP1A/ASTN2/HSP90AB1/TM9SF4/PICALM	26
BP	GO:1904377	positive regulation of protein localization to cell periphery	26/7096	63/18670	0.34	0.5838	0.4353	EZR/PLS1/ARF6/RAB11A/CIB1/SQSTM1/TNF/EPHB2/RHOG/CNST/LRP1/SPTBN1/CNPY4/RANGRF/NKD2/ITGA3/EGFR/GPSM2/STAC2/EPB41/TREM2/IFNG/KIF5B/EPB41L2/CLIP3/RER1	26
BP	GO:0001523	retinoid metabolic process	42/7096	104/18670	0.3424	0.5877	0.4381	RBP1/AKR1B1/PPARD/ALDH1A1/RDH10/ADH5/RETSAT/AKR1C3/APOE/DHRS3/DHRS9/LRP8/CYP1B1/RDH16/NAPEPLD/AKR1C1/CYP2S1/PLB1/LRP1/DGAT2/RDH12/CYP2D6/CYP1A2/CYP26B1/ALDH8A1/RDH5/SCPEP1/AKR1B10/ADH1B/GPC2/APOA1/BCO2/CYP26A1/GPC4/SDC3/CRABP2/RLBP1/ADH7/CYP2C8/RBP4/PNPLA4/STRA6	42
BP	GO:0014812	muscle cell migration	42/7096	104/18670	0.3424	0.5877	0.4381	IGF1/ANXA1/PPARD/GSTP1/PAK1/PLEKHO1/P2RY6/NET1/AIF1/CCL5/LRP1/CRK/PDGFB/PPARGC1A/DOCK5/CORO1B/MIR34A/PLXNA1/BMPR1A/NRP1/BCL2/TPM1/SERPINE1/HDAC4/ITGA2/PDGFA/FOXO4/LPAR1/NFE2L2/BIN3/SLIT2/MDM2/AAMP/MEGF10/NR4A3/ATP7A/TERT/ITGB1BP1/SSH1/SMO/PDGFD/MEF2C	42
BP	GO:0042737	drug catabolic process	56/7096	140/18670	0.3425	0.5877	0.4381	ASRGL1/QPRT/POR/ECE1/IL4I1/GNPDA1/NPL/PCBD1/FMO4/FAH/PRDX1/PCK2/NAGK/HBB/CYP2J2/MAOA/RENBP/CAT/CYP2S1/DPYD/GSTZ1/ALDH2/XPNPEP1/GPX3/QDPR/BDH1/IDUA/DAO/CTBS/OXCT1/CYP2D6/CYP1A2/PRDX6/HBQ1/ALLC/ADA/MAOB/AMT/CPN1/HP/SULT1B1/DBH/GPX1/SNCA/AMPD3/CYP2W1/ADAL/HBE1/CYP2A6/MPO/NNT/ADH7/CYP2C8/HAO1/CYP2U1/PIPOX	56
BP	GO:0017001	antibiotic catabolic process	24/7096	58/18670	0.3435	0.5892	0.4393	GNPDA1/NPL/ADH5/AKR1C3/ESD/PRDX1/PCK2/NAGK/HBB/RENBP/CAT/ALDH2/GPX3/PRDX6/HBQ1/AKR1B10/HP/SULT1B1/GPX1/SNCA/HBE1/MPO/NNT/ADH7	24
BP	GO:0048659	smooth muscle cell proliferation	68/7096	171/18670	0.3439	0.5898	0.4397	KLF4/IGF1/NAMPT/CDKN1A/AKR1B1/GNAI3/PTGS2/PPARD/TNFAIP3/S1PR1/STAT1/JAK2/GSTP1/IL15/TNF/HMOX1/SKP2/HMGCR/NOTCH3/NDRG2/IRAK4/PTAFR/PAK1/HPGD/P2RY6/TRAF6/AIF1/XRCC5/CCL5/IL6/PDGFB/PPARGC1A/MIR34A/BMPR1A/MMP9/GNAI2/BMP4/TPM1/TGM2/HDAC4/ID2/CDKN1B/ITGA2/CYBA/MAP3K5/EGFR/IL18/MDM2/TCF7L2/XRCC6/TGFB3/IFNG/VIP/NR4A3/HBEGF/IL12B/ABCC4/MMP2/TERT/MTOR/FOXP1/ERN1/CX3CL1/PDCD4/SERPINF2/PDGFD/MEF2C/APLN	68
BP	GO:0014032	neural crest cell development	33/7096	81/18670	0.3444	0.5905	0.4402	HTR2B/FN1/SEMA4B/KLHL12/KITLG/RDH10/ZEB2/HIF1A/NRG1/SEMA4A/SEMA4C/SEMA4D/EFNB1/BMP7/NOLC1/SEMA6B/KBTBD8/BMPR1A/NRP1/SEMA3B/ANXA6/BMP4/NRP2/CFL1/PEF1/SEMA5A/HES1/CORO1C/SEMA5B/MAPK1/RET/PHACTR4/SMO	33
BP	GO:0043401	steroid hormone mediated signaling pathway	73/7096	184/18670	0.3458	0.5928	0.442	VDR/PAQR7/NR4A2/GPAM/THRA/NCOA4/UBA5/PPARD/DDRGK1/CREBRF/YWHAH/CBFB/JAK2/AKAP13/SKP2/RAN/TRIM68/UBE3A/ZBTB7A/PAK1/NR3C2/NCOA3/NR1H2/LATS1/PMEPA1/GRIP1/NR1D2/UBR5/BUD31/SIRT1/BMP7/RHOXF1/PPARGC1A/CALCOCO1/NCOR1/KAT5/RXRA/CCNE1/BMP4/NEDD4/NR2E3/NR1H3/UFM1/CALR/BRCA1/PPARA/CLOCK/FHL2/RORA/ARNTL/NR4A3/TGFB1I1/STRN3/RNF4/DNAJA1/NR2F1/RB1/CARM1/ESRRB/NR2E1/DDX54/FOXP1/RHOA/PAQR8/NR2C2/TADA3/NRIP1/DAXX/LBH/NR1H4/NR2F6/TAF7/FOXH1	73
BP	GO:1901570	fatty acid derivative biosynthetic process	40/7096	99/18670	0.3462	0.5934	0.4424	ALOX5/ANXA1/ALOX5AP/CBR4/PTGS2/FAR2/HMGCL/MIF/ACSL5/MGST2/CD74/ELOVL5/AKR1C3/AACS/SCD/HPGD/ACSL4/ACLY/IL1B/TECR/ELOVL7/SIRT1/BDH1/BDH2/PNPLA8/PTGES3/ACSL6/HPGDS/FAR1/FABP5/GGT7/MGST3/GGTA1P/GGT5/ELOVL6/GGTLC1/HMGCLL1/CYP2C8/PTGS1/HSD17B12	40
BP	GO:0043331	response to dsRNA	22/7096	53/18670	0.347	0.5945	0.4432	DDX21/PMAIP1/FLOT1/P2RX7/IRAK3/NFKBIA/NFKB1/TICAM1/DDX58/NPM1/DHX9/MAVS/IFIH1/DDX1/IFNK/IFIT1/MUL1/RIOK3/MAPK1/TLR3/ZCCHC3/RFTN1	22
BP	GO:0051668	localization within membrane	59/7096	148/18670	0.349	0.5979	0.4457	STX7/RILPL1/DNM3/ITGB7/RAB11A/FLNA/CD2/PTPRC/SLC7A11/APOE/TGFB1/GRIPAP1/CLIP1/ITGAL/ITGA4/FZD9/USP46/CDK5/HRAS/OPHN1/GRIP1/NUMB/WDR19/RAP1A/RAB8A/TYROBP/NPTN/RAC1/ETV5/ARC/SAR1A/DNM1/DNM2/TBC1D20/ATP1B1/GRASP/MADCAM1/ADAM22/SYNGAP1/INSIG1/IQSEC2/LRRC7/DVL1/KIF17/PRKCZ/GPC4/RELN/PICK1/DAG1/ITGB1BP1/SSH1/GSG1L/RER1/LRP4/SEC24A/SHANK3/CD24/SEC31B/RFTN1	59
BP	GO:0072666	establishment of protein localization to vacuole	20/7096	48/18670	0.3506	0.6001	0.4474	NCOA4/TNFAIP3/LAMP2/VPS37B/VPS13A/M6PR/NAGPA/GNPTAB/VPS37C/CLU/GOSR2/VPS13D/NEDD4/HGS/VTI1A/VPS25/AP3B1/VTI1B/AP3M1/SNX16	20
BP	GO:2000059	negative regulation of ubiquitin-dependent protein catabolic process	20/7096	48/18670	0.3506	0.6001	0.4474	DDRGK1/HFE/FHIT/RYBP/CSNK2A2/SGTA/SDCBP/PML/UCHL5/KLHL40/USP7/MAP1A/WNT1/PSEN1/UBXN1/OGT/HSP90AB1/CLEC16A/BAG5/SMARCC1	20
BP	GO:0043279	response to alkaloid	45/7096	112/18670	0.3507	0.6001	0.4474	CRHBP/SLC8A1/PEA15/ATG7/FOSB/CASP6/HNMT/RELA/UBE3A/MAP1LC3A/PTK2B/MBD1/RYR1/HSPA5/CDK5/CASP3/TMED10/AIF1/CASP7/HOMER1/PPARGC1A/HDAC2/DNM2/PDX1/PITX3/GOT2/ADA/FADD/DNMT3A/PRKAA1/MDM2/CHRNB2/SRR/CASQ2/CAD/SMPD1/TMEM38B/HSP90AB1/CCNA2/MTOR/HDAC5/SNCA/EFTUD2/SPIDR/HTR3A	45
BP	GO:0007517	muscle organ development	160/7096	410/18670	0.3517	0.6017	0.4486	IGF1/HIVEP3/FOS/DLL1/MAPK12/MEF2A/SKI/RBPJ/WNT5A/EGR3/DISP1/PIM1/SMAD7/S1PR1/FHL3/RGS2/GPCPD1/FLOT1/KLHL41/VAMP5/EVC/EGR1/CXCL10/NUPR1/HMGCR/BTG2/UBE4B/MYL6B/TGFB1/PAK1/CFL2/HEG1/CHD2/NRG1/ITGA7/RYR1/ADARB1/TCF12/BMP2/PARP2/ACTC1/CDK5/SVIL/ITGA11/TAGLN/MYBPC3/EMD/UQCC2/NR1D2/S100B/LUC7L/PRR14/TIFAB/CREB1/DMD/SIRT1/SAV1/BASP1/HOMER1/EGR2/PAXBP1/CTDP1/G6PD/ZNF609/BCL9L/NLN/MYL6/SERP1/BTBD1/SRI/MYOG/RXRA/BMPR1A/BCL2/BMP4/TPM1/CYP26B1/HDAC4/YY1/KCNAB1/EID2/FHL1/KLF5/KCNK2/YBX3/ZBTB18/KLHL40/FOXO4/COPRS/HLX/FZD1/FGFRL1/FLNB/MYOZ1/CNTF/MYLK/COPS2/LMOD3/PPARA/CAV3/BIN3/HEY2/MYOM2/KAT2A/LAMA2/PRKAA1/HAMP/MAPK1/SHOX2/DNER/CNTFR/CASQ1/CAPN3/MEGF10/EPHB1/ARNTL/PKP2/MAPK11/PIN1/HBEGF/COL6A3/HLF/ZBTB42/RB1/FZD7/MSX1/ZNF689/MEIS1/GPX1/PITX1/POU6F1/MTOR/CHODL/RHOA/TAZ/HMG20B/PAX7/ENG/FZD2/P2RX2/PAX5/CHKB/USP19/MYH3/UNC45B/WNT10B/GJA1/GREM1/ACTA1/CACNA1H/SMO/WT1/ERBB3/KEL/RBP4/TLL2/MEF2C/FOXH1/MYF6/STRA6	160
BP	GO:1904427	positive regulation of calcium ion transmembrane transport	29/7096	71/18670	0.3523	0.6027	0.4493	CXCL9/CXCL11/SLC9A1/CXCL10/PKD2/KCNE3/P2RY6/ABL1/STIM2/GSTO1/PLCG2/G6PD/SUMO1/SRI/BAX/ATP1B1/F2R/CEMIP/STAC2/CASQ1/CAPN3/BDKRB1/EHD3/LACRT/CACNB3/SNCA/CX3CL1/KCNE2/NTSR1	29
BP	GO:0030879	mammary gland development	57/7096	143/18670	0.3529	0.6036	0.45	VDR/USF2/WNT5A/STAT6/CEBPB/JAK2/LRP5/TGFB1/HIF1A/LATS1/NRG1/ZBTB7B/VEGFA/STAT5A/PML/OAS2/TNFRSF11A/CREB1/ATP7B/CCND1/ETV5/KALRN/IRS2/MTX1/PAM/BCL2L11/ZNF703/BMP4/BAX/ID2/NME1/ITGA2/PPAT/KDM5B/GOT2/MST1/ORAI1/CAV3/MAPK1/NOTCH4/TGFB3/CAD/ATP7A/MSX1/ELF5/GPX1/CSF1R/RTN4/MGMT/FOXF1/SOCS2/GJA1/SMO/LBH/PTCH1/APLN/CSN3	57
BP	GO:0072348	sulfur compound transport	18/7096	43/18670	0.3541	0.6053	0.4513	SLC19A2/SLC25A19/SLC33A1/SLC38A7/SLC7A11/SLC26A11/SLC1A4/SLC25A10/LRRC8D/SLC26A8/SLC5A6/SLC26A4/NFE2L1/LRRC8A/SLC25A26/ABCD1/SLC26A10/CTNS	18
BP	GO:0086004	regulation of cardiac muscle cell contraction	18/7096	43/18670	0.3541	0.6053	0.4513	ATP1A1/FLNA/KCNE3/PDE4B/TRPM4/SUMO1/SRI/CTNNA3/HCN4/RANGRF/CAMK2D/DSC2/CAV3/ATP2A2/PKP2/FGF13/ATP1A2/BIN1	18
BP	GO:0034767	positive regulation of ion transmembrane transport	62/7096	156/18670	0.3552	0.607	0.4525	CCR2/KCNMB1/PINK1/CHP1/FLNA/CTSS/ACTN4/CXCL9/CXCL11/P2RX7/EPHB2/SLC9A1/CXCL10/TESC/PKD2/KCNE3/KCNIP2/ARL6IP1/PTAFR/P2RY6/ABL1/STIM2/GSTO1/PLCG2/DMD/CHCHD10/ATP1B2/G6PD/ARC/SUMO1/SRI/ATP1B3/ARF1/LRRC52/FXYD1/DNM2/BAX/ATP1B1/ADRB2/KCNQ1/F2R/CEMIP/AMIGO1/STAC2/PSEN1/CASQ1/TREM2/CAPN3/IFNG/KIF5B/BDKRB1/EHD3/LACRT/CACNB3/RELN/SNCA/CX3CL1/KCNE2/SHANK3/HTR3A/NTSR1/WNK2	62
BP	GO:0016572	histone phosphorylation	16/7096	38/18670	0.3577	0.61	0.4548	JAK2/PRKCD/CDK5/IL1B/MAP3K12/CDK9/ATM/AKAP8/ZMPSTE24/PRKAA1/FMR1/VRK1/CCNA2/AURKA/UBE2B/PRKCA	16
BP	GO:0046326	positive regulation of glucose import	16/7096	38/18670	0.3577	0.61	0.4548	IGF1/MEF2A/C2CD5/INSR/RAP1A/CREBL2/IRS2/ITLN1/CLTCL1/RHOQ/RNASEL/NFE2L2/ADIPOR2/TERT/APPL1/KLF15	16
BP	GO:0046825	regulation of protein export from nucleus	16/7096	38/18670	0.3577	0.61	0.4548	BARD1/GSK3B/IFI27/CDK5/SFN/SP100/EMD/IL1B/PRKACA/TXN/RIOK2/MDM2/TCF7L2/YWHAE/XPO4/CTDSPL2	16
BP	GO:0048009	insulin-like growth factor receptor signaling pathway	16/7096	38/18670	0.3577	0.61	0.4548	IGF1/GIGYF2/IGFBP4/BMP2/IGF1R/IGF2R/PHIP/IGFBP2/BMP5/PLCB1/WNT1/CRIM1/CILP/CDH3/GHRH/GHR	16
BP	GO:0071604	transforming growth factor beta production	16/7096	38/18670	0.3577	0.61	0.4548	PTGS2/HIF1A/LTBP3/FURIN/CREB1/ATP6AP2/TYROBP/LGALS9/CD2AP/LAPTM4B/CD34/HSP90AB1/CDH3/CX3CL1/CD24/SERPINF2	16
BP	GO:0097352	autophagosome maturation	16/7096	38/18670	0.3577	0.61	0.4548	MCOLN1/ATG14/LAMP2/MAP1LC3A/CLN3/VPS33A/MAP1LC3C/PHF23/TSG101/ADRB2/SMCR8/GABARAPL1/CLEC16A/VPS16/SNAP29/VCP	16
BP	GO:2000279	negative regulation of DNA biosynthetic process	16/7096	38/18670	0.3577	0.61	0.4548	DUSP1/HNRNPA1/DNAJC2/DCP2/NAT10/HNRNPC/XRN1/PARP3/KCNK2/ACD/CTC1/GNL3L/MEN1/POT1/GJA1/BMPR2	16
BP	GO:0006721	terpenoid metabolic process	48/7096	120/18670	0.3583	0.6109	0.4554	ALDH3A2/RBP1/SRD5A1/AKR1B1/PPARD/ALDH1A1/RDH10/ADH5/RETSAT/AKR1C3/APOE/DHRS3/DHRS9/LRP8/HMGCS1/CYP1B1/RDH16/NAPEPLD/HTRA2/AKR1C1/CYP2S1/PLB1/FDPS/LRP1/DGAT2/RDH12/CYP2D6/CYP1A2/CYP26B1/ALDH8A1/RDH5/SCPEP1/AKR1B10/ADH1B/EGFR/GPC2/APOA1/BCO2/CYP26A1/GPC4/SDC3/CRABP2/RLBP1/ADH7/CYP2C8/RBP4/PNPLA4/STRA6	48
BP	GO:0014910	regulation of smooth muscle cell migration	34/7096	84/18670	0.3587	0.6114	0.4558	IGF1/PPARD/GSTP1/PAK1/P2RY6/AIF1/CCL5/LRP1/CRK/PDGFB/PPARGC1A/DOCK5/CORO1B/MIR34A/PLXNA1/BMPR1A/NRP1/BCL2/TPM1/SERPINE1/HDAC4/ITGA2/PDGFA/FOXO4/LPAR1/NFE2L2/SLIT2/MDM2/NR4A3/ATP7A/TERT/SSH1/PDGFD/MEF2C	34
BP	GO:0030521	androgen receptor signaling pathway	25/7096	61/18670	0.3608	0.6139	0.4577	NCOA4/RAN/TRIM68/UBE3A/ZBTB7A/NCOA3/PMEPA1/GRIP1/BUD31/SIRT1/PPARGC1A/NCOR1/KAT5/CCNE1/BRCA1/FHL2/TGFB1I1/RNF4/DNAJA1/RB1/FOXP1/RHOA/NRIP1/DAXX/FOXH1	25
BP	GO:0090303	positive regulation of wound healing	25/7096	61/18670	0.3608	0.6139	0.4577	ANXA1/CLEC7A/PPARD/CD36/ARFGEF1/TLR4/HRAS/THBD/HPSE/SERPINE1/KANK1/PLEK/DMTN/F2R/NFE2L2/MYLK/INSL3/REG3G/CAPN3/HRG/HBEGF/F3/MTOR/ENPP4/SERPINF2	25
BP	GO:0006370	7-methylguanosine mRNA capping	14/7096	33/18670	0.361	0.6139	0.4577	CCNH/GTF2F2/POLR2L/POLR2H/RNGTT/GTF2H4/GTF2F1/CMTR1/POLR2F/POLR2D/POLR2K/ERCC2/CMTR2/POLR2I	14
BP	GO:0006471	protein ADP-ribosylation	14/7096	33/18670	0.361	0.6139	0.4577	PARP9/SIRT4/KAT2B/ARF4/PARP2/PARP16/PARP12/XRCC1/PARP3/TIPARP/IFNG/PARP11/PARP6/PNKP	14
BP	GO:0010464	regulation of mesenchymal cell proliferation	14/7096	33/18670	0.361	0.6139	0.4577	WNT5A/LMNA/STAT1/MYC/LRP5/VEGFA/IRS2/PHF14/BMPR1A/BMP4/PDGFA/SHOX2/FOXF1/SMO	14
BP	GO:0042755	eating behavior	14/7096	33/18670	0.361	0.6139	0.4577	STAT3/UCHL1/LEP/NAPEPLD/BBS12/NMUR2/RMI1/CPT1A/OPRD1/OPRL1/MTOR/IAPP/P2RY1/GHRL	14
BP	GO:1902692	regulation of neuroblast proliferation	14/7096	33/18670	0.361	0.6139	0.4577	CX3CR1/TGFB1/HIF1A/CTNNA1/VEGFA/LRRK2/ASPM/DISC1/KCTD11/DCT/CX3CL1/OTP/SMO/ZNF335	14
BP	GO:0021675	nerve development	32/7096	79/18670	0.3631	0.6139	0.4577	LRIG2/EPHB2/UNC13B/FBXO45/TCIRG1/ITGA4/ADARB1/ATP8B1/TIFAB/AFG3L2/EGR2/SULF2/DICER1/NRP1/NRP2/CTSV/LPAR1/HES1/KCNA2/HOXB1/CHRNB2/TMEM126A/RPL24/POU4F3/EPHB1/PLXNA3/RET/NAV2/DAG1/HOXA3/ERBB3/LRIG1	32
BP	GO:0031110	regulation of microtubule polymerization or depolymerization	32/7096	79/18670	0.3631	0.6139	0.4577	STMN1/MAP1S/CIB1/PSRC1/PAK1/CLIP1/STMN3/ABL1/CDK5RAP2/ARHGEF2/MAPRE1/SKA2/RAC1/MAPRE2/CDH5/CDKN1B/RANGRF/SLC39A12/CLASP2/CAV3/TUBB4A/MAP1A/KATNB1/SLAIN2/NAV3/TRPV4/SNCA/CLIP3/TTBK2/MET/FGF13/SKA3	32
BP	GO:0061448	connective tissue development	107/7096	273/18670	0.3638	0.6139	0.4577	CRIP1/POR/WNT5A/CHSY1/THRA/PPARD/SLC25A25/SMAD5/DDRGK1/CD44/CTSK/EVC/EGR1/ZNF516/IMPAD1/THBS3/LRP5/RELA/CDK4/MAF/ARRDC3/TGFB1/AACS/HIF1A/LEP/ROR2/SRF/HYAL2/DYRK1B/LOXL2/CSGALNACT1/IFT80/BMP2/SPTLC2/LTBP3/MEX3C/SATB2/CREB3L2/CYTL1/ACTA2/CHST11/BBS2/SIRT1/TRPM4/BMP7/MKKS/SLC39A13/DGAT2/CHI3L1/ADAMTS12/PDGFB/PPARGC1A/KLF7/SULF2/BBS4/HOXC4/OXCT1/BMP5/FTO/BMPR1A/ANXA6/BMP4/ID2/COL7A1/TIMP1/TYMS/HYAL3/ZMPSTE24/COL20A1/COL2A1/SCIN/ANXA2P2/SHOX2/SNAI1/ATP7A/PTHLH/SNX19/CD34/COL6A3/MGP/SOX5/WNT2B/CARM1/MSX1/GLG1/PITX1/COL11A2/TGFBI/ANXA2/TRPV4/PAX7/HOXA3/ZBTB16/WNT7A/PAXIP1/WNT10B/CER1/GREM1/BMPR1B/NR1H4/WT1/PDGFD/GHRL/FGF6/MEF2C/BMPR2/GDF5	107
BP	GO:0001516	prostaglandin biosynthetic process	12/7096	28/18670	0.3642	0.6139	0.4577	ANXA1/PTGS2/MIF/CD74/AKR1C3/IL1B/SIRT1/PNPLA8/PTGES3/HPGDS/FABP5/PTGS1	12
BP	GO:0033598	mammary gland epithelial cell proliferation	12/7096	28/18670	0.3642	0.6139	0.4577	WNT5A/STAT6/CEBPB/CCND1/ZNF703/BAX/ID2/KDM5B/MST1/MAPK1/GPX1/RTN4	12
BP	GO:0034368	protein-lipid complex remodeling	12/7096	28/18670	0.3642	0.6139	0.4577	APOC1/SCARB1/PLA2G7/CETP/APOE/ABCA5/APOA5/LCAT/ABCG1/APOA1/MPO/ALB	12
BP	GO:0034369	plasma lipoprotein particle remodeling	12/7096	28/18670	0.3642	0.6139	0.4577	APOC1/SCARB1/PLA2G7/CETP/APOE/ABCA5/APOA5/LCAT/ABCG1/APOA1/MPO/ALB	12
BP	GO:0042634	regulation of hair cycle	12/7096	28/18670	0.3642	0.6139	0.4577	WNT5A/TNF/TRADD/HPSE/CLOCK/ARNTL/TERT/CDH3/FOXN1/WNT10B/SMO/TRPV3	12
BP	GO:0046457	prostanoid biosynthetic process	12/7096	28/18670	0.3642	0.6139	0.4577	ANXA1/PTGS2/MIF/CD74/AKR1C3/IL1B/SIRT1/PNPLA8/PTGES3/HPGDS/FABP5/PTGS1	12
BP	GO:0051984	positive regulation of chromosome segregation	12/7096	28/18670	0.3642	0.6139	0.4577	SMC5/SMC6/NSMCE2/SFPQ/ESPL1/ANAPC5/RCC2/DLGAP5/ANAPC4/RB1/ANAPC11/FEN1	12
BP	GO:0052312	modulation of transcription in other organism involved in symbiotic interaction	12/7096	28/18670	0.3642	0.6139	0.4577	CHD1/TFAP4/TAF11/CCL5/CTDP1/PSMC3/INPP5K/HPN/CCNT1/CCL4/NUCKS1/TARDBP	12
BP	GO:1904994	regulation of leukocyte adhesion to vascular endothelial cell	12/7096	28/18670	0.3642	0.6139	0.4577	KLF4/CCR2/TNF/CXCL12/RELA/PTAFR/TRAF6/ITGA4/ETS1/NFAT5/RHOA/MIR146A	12
BP	GO:0090183	regulation of kidney development	23/7096	56/18670	0.3652	0.6139	0.4577	STAT1/LGR4/MYC/EGR1/MAGED1/TGFB1/VEGFA/PAX8/BASP1/BMP7/PDGFB/FLCN/MMP9/BMP4/PDGFA/HNF1B/RET/TACSTD2/WNT2B/SMO/CD24/WT1/PDGFD	23
BP	GO:1903078	positive regulation of protein localization to plasma membrane	23/7096	56/18670	0.3652	0.6139	0.4577	EZR/PLS1/ARF6/RAB11A/CIB1/SQSTM1/TNF/EPHB2/RHOG/CNST/LRP1/SPTBN1/CNPY4/RANGRF/NKD2/ITGA3/EGFR/STAC2/TREM2/IFNG/KIF5B/CLIP3/RER1	23
BP	GO:0006297	nucleotide-excision repair, DNA gap filling	10/7096	23/18670	0.3668	0.6139	0.4577	RPA1/POLD4/POLD2/RFC3/PCNA/XRCC1/UBC/LIG4/POLD1/LIG3	10
BP	GO:0032753	positive regulation of interleukin-4 production	10/7096	23/18670	0.3668	0.6139	0.4577	NLRP3/CEBPB/IL20RB/HLA-E/LGALS9/TNFSF4/HAVCR2/PRKCZ/PRKCQ/CD3E	10
BP	GO:0032959	inositol trisphosphate biosynthetic process	10/7096	23/18670	0.3668	0.6139	0.4577	PTAFR/PTK2B/P2RY6/PLCG2/PLCL1/PLCD1/PLCB1/PLCD4/PLCL2/P2RY1	10
BP	GO:0035561	regulation of chromatin binding	10/7096	23/18670	0.3668	0.6139	0.4577	PARP9/MEPCE/CTBP2/ZNF304/GMNN/BTAF1/TDG/DTX3L/KDM4D/MED25	10
BP	GO:0051151	negative regulation of smooth muscle cell differentiation	10/7096	23/18670	0.3668	0.6139	0.4577	NFATC3/MED28/PDGFB/NFATC1/ANKRD17/NFATC2/FOXO4/HEY2/PRDM6/PDCD4	10
BP	GO:0051589	negative regulation of neurotransmitter transport	10/7096	23/18670	0.3668	0.6139	0.4577	RAP1B/SYT11/RGS2/LILRB1/PNKD/RAP1A/MAOB/FMR1/SYT4/SNCA	10
BP	GO:0051882	mitochondrial depolarization	10/7096	23/18670	0.3668	0.6139	0.4577	GCLM/P2RX7/FZD9/ABL1/GCLC/LRRK2/BCL2/PPP2R3C/MLLT11/ABCD1	10
BP	GO:0090140	regulation of mitochondrial fission	10/7096	23/18670	0.3668	0.6139	0.4577	PINK1/TMEM135/MIEF1/FIS1/DDHD1/LRRK2/PPARGC1A/DNM1L/MUL1/INF2	10
BP	GO:1903429	regulation of cell maturation	10/7096	23/18670	0.3668	0.6139	0.4577	CLEC7A/BCL11A/LRRK2/BCL2/MAP3K13/RET/MTOR/AURKA/TRIM58/KIF14	10
BP	GO:2000050	regulation of non-canonical Wnt signaling pathway	10/7096	23/18670	0.3668	0.6139	0.4577	WNT5A/CSNK1D/IFT80/ABL1/SFRP4/RNF213/CSNK1E/MKS1/ANKRD6/DAAM2	10
BP	GO:2000726	negative regulation of cardiac muscle cell differentiation	10/7096	23/18670	0.3668	0.6139	0.4577	DLL1/RGS2/PAK1/BMP2/CTDP1/G6PD/YY1/PPARA/CAV3/FZD7	10
BP	GO:0000212	meiotic spindle organization	6/7096	13/18670	0.3674	0.6139	0.4577	ESPL1/ASPM/MYH9/MOS/TUBG2/AURKA	6
BP	GO:0001967	suckling behavior	6/7096	13/18670	0.3674	0.6139	0.4577	UBR3/PEX13/GLS/DERL2/CNTFR/APP	6
BP	GO:0002087	regulation of respiratory gaseous exchange by neurological system process	6/7096	13/18670	0.3674	0.6139	0.4577	TSHZ3/GLS/TLX3/ATP1A2/NLGN2/PBX3	6
BP	GO:0006553	lysine metabolic process	6/7096	13/18670	0.3674	0.6139	0.4577	ALDH7A1/PHYKPL/OGDH/AASDHPPT/HYKK/PIPOX	6
BP	GO:0007494	midgut development	6/7096	13/18670	0.3674	0.6139	0.4577	WNT5A/DAB1/EGFR/RET/FOXF1/SMO	6
BP	GO:0009650	UV protection	6/7096	13/18670	0.3674	0.6139	0.4577	ERCC4/CAT/ERCC1/ERCC2/GPX1/FEN1	6
BP	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway	6/7096	13/18670	0.3674	0.6139	0.4577	PTPN2/LRP1/PHF14/HGS/SNCA/PTPRJ	6
BP	GO:0010839	negative regulation of keratinocyte proliferation	6/7096	13/18670	0.3674	0.6139	0.4577	VDR/SFN/INTU/KLF9/SLURP1/CD109	6
BP	GO:0014842	regulation of skeletal muscle satellite cell proliferation	6/7096	13/18670	0.3674	0.6139	0.4577	STAT3/PPARD/JAK2/PAXBP1/MYOG/EPHB1	6
BP	GO:0018206	peptidyl-methionine modification	6/7096	13/18670	0.3674	0.6139	0.4577	NAA20/METAP2/NAA16/APOA1/NAA15/NAA60	6
BP	GO:0019627	urea metabolic process	6/7096	13/18670	0.3674	0.6139	0.4577	ARG2/NAGS/CEBPA/SLC25A15/NMRAL1/NR1H4	6
BP	GO:0030205	dermatan sulfate metabolic process	6/7096	13/18670	0.3674	0.6139	0.4577	VCAN/CSPG4/IDUA/CHST14/BCAN/CHST12	6
BP	GO:0031115	negative regulation of microtubule polymerization	6/7096	13/18670	0.3674	0.6139	0.4577	STMN1/MAPRE1/CDH5/TUBB4A/SNCA/CLIP3	6
BP	GO:0032754	positive regulation of interleukin-5 production	6/7096	13/18670	0.3674	0.6139	0.4577	IL17RA/NLRP3/IL1RAP/TSLP/PRKCZ/IL17RB	6
BP	GO:0033127	regulation of histone phosphorylation	6/7096	13/18670	0.3674	0.6139	0.4577	IL1B/CDK9/ATM/AKAP8/FMR1/UBE2B	6
BP	GO:0035563	positive regulation of chromatin binding	6/7096	13/18670	0.3674	0.6139	0.4577	PARP9/CTBP2/GMNN/DTX3L/KDM4D/MED25	6
BP	GO:0035627	ceramide transport	6/7096	13/18670	0.3674	0.6139	0.4577	PSAP/PLEKHA8/CPTP/PLEKHA3/GLTP/PLEKHA8P1	6
BP	GO:0035745	T-helper 2 cell cytokine production	6/7096	13/18670	0.3674	0.6139	0.4577	NLRP3/DENND1B/RSAD2/IL6/PRKCZ/TBX21	6
BP	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein	6/7096	13/18670	0.3674	0.6139	0.4577	SOCS3/PPP2CA/PTPN2/INPP5F/SOCS1/MIR146A	6
BP	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway	6/7096	13/18670	0.3674	0.6139	0.4577	IGF1/IGFBP4/PHIP/WNT1/CDH3/GHRH	6
BP	GO:0045006	DNA deamination	6/7096	13/18670	0.3674	0.6139	0.4577	CDADC1/APOBEC3G/APOBEC3C/EXOSC3/EXOSC6/EXOSC5	6
BP	GO:0050713	negative regulation of interleukin-1 beta secretion	6/7096	13/18670	0.3674	0.6139	0.4577	NLRP3/TNFAIP3/SERPINB1/PML/CPTP/APOA1	6
BP	GO:0050872	white fat cell differentiation	6/7096	13/18670	0.3674	0.6139	0.4577	FABP4/PER2/CTBP2/AACS/CEBPA/SIRT1	6
BP	GO:0060100	positive regulation of phagocytosis, engulfment	6/7096	13/18670	0.3674	0.6139	0.4577	APPL2/RAB31/CD36/ITGA2/ABCA7/TREM2	6
BP	GO:0060123	regulation of growth hormone secretion	6/7096	13/18670	0.3674	0.6139	0.4577	ITSN1/KALRN/SERP1/GHRH/GHRL/KISS1	6
BP	GO:0060576	intestinal epithelial cell development	6/7096	13/18670	0.3674	0.6139	0.4577	CDKN1A/HIF1A/KLF5/TYMS/YIPF6/C1GALT1	6
BP	GO:0061029	eyelid development in camera-type eye	6/7096	13/18670	0.3674	0.6139	0.4577	SRF/HDAC2/INHBA/EGFR/GRHL3/STRA6	6
BP	GO:0061430	bone trabecula morphogenesis	6/7096	13/18670	0.3674	0.6139	0.4577	SBNO2/THBS3/SEMA4D/MMP2/WNT10B/GREM1	6
BP	GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	6/7096	13/18670	0.3674	0.6139	0.4577	NOD2/TNFAIP3/NFKBIA/RELA/TLR4/PTPN22	6
BP	GO:0070914	UV-damage excision repair	6/7096	13/18670	0.3674	0.6139	0.4577	DDB1/SIRT1/ACTR5/ERCC1/DDB2/CUL4B	6
BP	GO:0071287	cellular response to manganese ion	6/7096	13/18670	0.3674	0.6139	0.4577	ATF4/HSPA5/EIF2S1/LRRK2/APP/SLC30A10	6
BP	GO:0090179	planar cell polarity pathway involved in neural tube closure	6/7096	13/18670	0.3674	0.6139	0.4577	WNT5A/DVL2/FZD1/DVL1/FZD2/GRHL3	6
BP	GO:0090646	mitochondrial tRNA processing	6/7096	13/18670	0.3674	0.6139	0.4577	TRMT5/TRMT61B/PUS1/HSD17B10/MTO1/TRMT10C	6
BP	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response	6/7096	13/18670	0.3674	0.6139	0.4577	PTPN2/TMEM33/BCL2L11/BAX/ERN1/BAK1	6
BP	GO:1900272	negative regulation of long-term synaptic potentiation	6/7096	13/18670	0.3674	0.6139	0.4577	CX3CR1/APOE/ABL1/AGER/TYROBP/APP	6
BP	GO:1901160	primary amino compound metabolic process	6/7096	13/18670	0.3674	0.6139	0.4577	SRD5A1/CHKA/TPH2/ATP7A/AZIN2/AGMAT	6
BP	GO:1901550	regulation of endothelial cell development	6/7096	13/18670	0.3674	0.6139	0.4577	S1PR3/TNF/VEGFA/IL1B/CDH5/ROCK2	6
BP	GO:1902430	negative regulation of amyloid-beta formation	6/7096	13/18670	0.3674	0.6139	0.4577	IGF1/APOE/CLU/ABCA7/PIN1/BIN1	6
BP	GO:1902855	regulation of non-motile cilium assembly	6/7096	13/18670	0.3674	0.6139	0.4577	MAP4/BBS4/MAK/DNM2/RP1/WRAP73	6
BP	GO:1902947	regulation of tau-protein kinase activity	6/7096	13/18670	0.3674	0.6139	0.4577	EGR1/HGF/CLU/IFNG/HSP90AB1/RB1	6
BP	GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding	6/7096	13/18670	0.3674	0.6139	0.4577	DDRGK1/FBXW7/ENHO/NSD1/ZNF593/ZMPSTE24	6
BP	GO:1903140	regulation of establishment of endothelial barrier	6/7096	13/18670	0.3674	0.6139	0.4577	S1PR3/TNF/VEGFA/IL1B/CDH5/ROCK2	6
BP	GO:1903726	negative regulation of phospholipid metabolic process	6/7096	13/18670	0.3674	0.6139	0.4577	SLC27A1/APOC1/PIK3IP1/PDGFB/PDGFA/LPCAT1	6
BP	GO:1905155	positive regulation of membrane invagination	6/7096	13/18670	0.3674	0.6139	0.4577	APPL2/RAB31/CD36/ITGA2/ABCA7/TREM2	6
BP	GO:0099601	regulation of neurotransmitter receptor activity	30/7096	74/18670	0.3677	0.6139	0.4577	CRHBP/CCR2/PINK1/KLHL24/NETO2/EPHB2/ANXA3/PTK2B/CNIH3/CDK5/DAPK1/HOMER1/PPARGC1A/ARC/SHISA9/ADRB2/SHANK1/RASGRF1/LRRC7/IFNG/SLURP1/RELN/APP/GSG1L/SHISA8/NLGN2/SHANK3/GRIA2/MEF2C/NPTXR	30
BP	GO:1903036	positive regulation of response to wounding	30/7096	74/18670	0.3677	0.6139	0.4577	ANXA1/CLEC7A/GRN/PPARD/CD36/ARFGEF1/TLR4/HRAS/LRP1/THBD/HPSE/SERPINE1/KANK1/NDEL1/PLEK/DMTN/F2R/NFE2L2/CNTF/MYLK/INSL3/REG3G/CAPN3/ATP7A/HRG/HBEGF/F3/MTOR/ENPP4/SERPINF2	30
BP	GO:0002098	tRNA wobble uridine modification	8/7096	18/18670	0.3683	0.6139	0.4577	DPH3/ELP4/ELP3/ALKBH8/MOCS3/ELP2/MTO1/GTPBP3	8
BP	GO:0007221	positive regulation of transcription of Notch receptor target	8/7096	18/18670	0.3683	0.6139	0.4577	RBPJ/STAT1/KAT2B/NOTCH3/PLXND1/DLGAP5/NOTCH4/WWC1	8
BP	GO:0007252	I-kappaB phosphorylation	8/7096	18/18670	0.3683	0.6139	0.4577	CX3CR1/TLR2/DDRGK1/TLR4/TRAF2/TLR3/CX3CL1/CHUK	8
BP	GO:0008090	retrograde axonal transport	8/7096	18/18670	0.3683	0.6139	0.4577	SOD1/PAFAH1B1/NDEL1/MAP1A/KIF1B/KIF5B/KIF1C/MGARP	8
BP	GO:0031998	regulation of fatty acid beta-oxidation	8/7096	18/18670	0.3683	0.6139	0.4577	ACACB/IRS2/MLYCD/TYSND1/CPT1A/PPARA/MTOR/ABCD1	8
BP	GO:0035089	establishment of apical/basal cell polarity	8/7096	18/18670	0.3683	0.6139	0.4577	WNT5A/OPHN1/SH3BP1/FSCN1/MSN/RHOA/FOXF1/LAMA1	8
BP	GO:0042772	DNA damage response, signal transduction resulting in transcription	8/7096	18/18670	0.3683	0.6139	0.4577	CDKN1A/MAD2L2/TFAP4/SP100/MUC1/KAT5/BRCA1/ING4	8
BP	GO:1904872	regulation of telomerase RNA localization to Cajal body	8/7096	18/18670	0.3683	0.6139	0.4577	RUVBL2/RUVBL1/NAF1/DCP2/NHP2/CCT4/CCT8/NOP10	8
BP	GO:0000731	DNA synthesis involved in DNA repair	21/7096	51/18670	0.3698	0.616	0.4592	CDKN2D/MAD2L2/RPA1/ZBTB1/UBE2L6/POLD4/WRNIP1/POLD2/ISG15/SIRT1/POLI/RFC3/POLH/NPLOC4/PCNA/UBC/DTL/USP10/POLD1/POLA1/VCP	21
BP	GO:0021545	cranial nerve development	21/7096	51/18670	0.3698	0.616	0.4592	EPHB2/TCIRG1/ADARB1/ATP8B1/TIFAB/EGR2/NRP1/NRP2/LPAR1/HES1/KCNA2/HOXB1/CHRNB2/TMEM126A/RPL24/POU4F3/EPHB1/PLXNA3/NAV2/HOXA3/ERBB3	21
BP	GO:0045103	intermediate filament-based process	21/7096	51/18670	0.3698	0.616	0.4592	SOD1/VIM/KLHL24/SYNC/PLEC/AGFG1/CLN8/RAF1/EVPL/DNAJB6/CSNK1A1/TOR1A/NDEL1/ATXN3/TCHH/PKP2/INA/KRT74/BFSP2/KRT14/MACF1	21
BP	GO:0034381	plasma lipoprotein particle clearance	28/7096	69/18670	0.3725	0.6202	0.4624	CSK/NPC2/LIPA/APOC1/SCARB1/SOAT1/HMOX1/APOE/HDLBP/CD36/LRPAP1/HNRNPK/LDLR/LMF1/EHD1/APOBR/DGAT2/AP2A2/AP2S1/AP2A1/ANXA2P2/CES3/APOA1/NCEH1/AP2M1/ANXA2/NR1H4/CNPY2	28
BP	GO:0030490	maturation of SSU-rRNA	19/7096	46/18670	0.3746	0.6233	0.4647	TSR1/WDR46/KRI1/ABT1/NAT10/RPS21/RPS19/RCL1/DCAF13/RIOK2/NOL10/RIOK3/RPS16/FAM207A/TSR2/MRPS9/UTP3/RRS1/DDX52	19
BP	GO:0050919	negative chemotaxis	19/7096	46/18670	0.3746	0.6233	0.4647	WNT5A/SEMA4B/NRG1/SEMA4A/SEMA4C/SEMA4D/SEMA6B/SEMA3B/NRP2/PDGFA/SEMA5A/UNC5C/SLIT2/SEMA5B/APOA1/PLXNA3/LGR6/RHOA/SLIT3	19
BP	GO:0060711	labyrinthine layer development	19/7096	46/18670	0.3746	0.6233	0.4647	JUNB/SOCS3/RBPJ/MAP2K1/VASH1/CASP8/HEY1/BMP7/PCDH12/DNAJB6/BMP5/SPINT1/GRB2/FZD5/HES1/PLCD1/HEY2/MAPK1/GRHL2	19
BP	GO:0002181	cytoplasmic translation	40/7096	100/18670	0.3762	0.6256	0.4664	DPH3/FTSJ1/METTL3/CNBP/RBM4/EIF2D/EIF3M/NCK1/EIF4B/DPH5/DHX9/RPL8/EIF3I/EIF2S2/EIF4H/EIF3G/RPS21/GSPT2/MCTS1/DPH2/CPEB1/ETF1/EIF3B/EIF5/CPEB3/YBX3/ZC3H15/TICRR/EIF3J/UNK/FMR1/EIF4G1/RPL24/RPL26L1/RPL32/MTOR/EIF3L/DNAJC24/CPEB2/RPL10A	40
BP	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	40/7096	100/18670	0.3762	0.6256	0.4664	FPR2/FPR1/CX3CR1/GNB1/S1PR1/GNA15/P2RY8/P2RY6/CMKLR1/P2RY12/HOMER1/LPAR6/BICD1/C3AR1/NMUR2/TGM2/GPR27/LPAR3/GPR18/LPAR1/CHRM2/F2R/GRPR/CXCR2/TACR1/GPR35/P2RY4/VIP/OPRD1/OPRL1/P2RY10/C5AR2/CCKBR/NMBR/GPR20/GNA11/P2RY1/KISS1/NTSR2/CCKAR	40
BP	GO:0098754	detoxification	52/7096	131/18670	0.3763	0.6256	0.4664	NQO1/S100A9/GCH1/ALOX5AP/SOD1/PTGS2/ACAA1/ADH5/MGST2/GSTP1/TNF/GSR/APOE/TXNRD1/GPX7/AKR7A3/ESD/CD36/PRDX1/TXNDC17/AKR1A1/HBB/CAT/GSTO1/GSTZ1/GPX3/IPCEF1/GSTA1/BMP7/GPX4/GSTM3/RDH12/MGST1/PRDX6/HBQ1/AKR1B10/NFE2L2/DHFR/TXN/SESN1/MGST3/ATP7A/HP/GPX1/MARC2/SRXN1/HBE1/MPO/NNT/SESN2/PTGS1/ALB	52
BP	GO:0045600	positive regulation of fat cell differentiation	26/7096	64/18670	0.3775	0.6272	0.4676	METRNL/ZFP36/FNDC5/PTGS2/PPARD/CEBPB/LRP5/AAMDC/WDFY2/SYAP1/NAPEPLD/ZBTB7B/CEBPA/BMP2/CMKLR1/CREB1/SAV1/TRPM4/CREBL2/TMEM64/ID2/ASXL2/KLF5/CARM1/VSTM2A/ZBTB16	26
BP	GO:0046503	glycerolipid catabolic process	26/7096	64/18670	0.3775	0.6272	0.4676	FABP4/ENPP2/GDE1/ABHD6/ABHD12/GPCPD1/APOC1/SCARB1/MGLL/APOE/PNPLA6/PNPLA3/PLA2G15/LDLR/FABP3/APOA5/PNPLA8/DAGLB/PRDX6/PNPLA5/INPP5F/FABP5/APOA1/PIK3CG/ABHD16A/PNPLA4	26
BP	GO:1904064	positive regulation of cation transmembrane transport	57/7096	144/18670	0.3779	0.6278	0.4681	CCR2/KCNMB1/PINK1/CHP1/FLNA/CTSS/ACTN4/CXCL9/CXCL11/EPHB2/SLC9A1/CXCL10/TESC/PKD2/KCNE3/KCNIP2/P2RY6/ABL1/STIM2/GSTO1/PLCG2/DMD/CHCHD10/ATP1B2/G6PD/ARC/SUMO1/SRI/ATP1B3/ARF1/LRRC52/FXYD1/DNM2/BAX/ATP1B1/ADRB2/KCNQ1/F2R/CEMIP/AMIGO1/STAC2/CASQ1/TREM2/CAPN3/IFNG/KIF5B/BDKRB1/EHD3/LACRT/CACNB3/RELN/SNCA/CX3CL1/KCNE2/SHANK3/NTSR1/WNK2	57
BP	GO:0019985	translesion synthesis	17/7096	41/18670	0.3796	0.6301	0.4697	MAD2L2/RPA1/ZBTB1/UBE2L6/POLD4/POLD2/ISG15/POLI/RFC3/POLH/NPLOC4/PCNA/UBC/DTL/USP10/POLD1/VCP	17
BP	GO:0030835	negative regulation of actin filament depolymerization	17/7096	41/18670	0.3796	0.6301	0.4697	TMOD3/LIMA1/TWF2/RDX/CAPZA2/SWAP70/CAPG/CAPZA1/SPTBN1/AVIL/TRIOBP/ADD3/DMTN/LMOD3/SCIN/SPTA1/SPTBN2	17
BP	GO:0035337	fatty-acyl-CoA metabolic process	17/7096	41/18670	0.3796	0.6301	0.4697	CBR4/FAR2/ACOT7/ACSL5/ELOVL5/SCD/ACSL4/ACLY/TECR/HSD17B4/ELOVL7/DGAT2/ACSL6/FAR1/ELOVL6/ABCD1/HSD17B12	17
BP	GO:0009755	hormone-mediated signaling pathway	92/7096	235/18670	0.3821	0.6342	0.4728	CRHBP/VDR/SLC27A1/PAQR7/APPL2/NR4A2/NUP62/GPAM/THRA/NCOA4/UBA5/PPARD/ADIPOR1/DDRGK1/CREBRF/YWHAH/LGR4/CBFB/JAK2/AKAP13/SKP2/RAN/TRIM68/UBE3A/ZBTB7A/PAK1/NR3C2/NCOA3/NR1H2/LATS1/ASIP/PMEPA1/GRIP1/NR1D2/UBR5/CSNK2B/BUD31/SIRT1/BMP7/RHOXF1/PPARGC1A/CALCOCO1/NCOR1/KAT5/RXRA/CCNE1/BMP4/NEDD4/NR2E3/NR1H3/UFM1/CALR/BRCA1/PPARA/CLOCK/FHL2/ADIPOR2/GPHB5/LGR5/RORA/ARNTL/NR4A3/TGFB1I1/STRN3/LATS2/RNF4/DNAJA1/NR2F1/RB1/FSHR/REN/RXFP2/CARM1/ESRRB/NR2E1/DDX54/FOXP1/RHOA/PAQR8/NR2C2/TADA3/APPL1/LANCL2/NRIP1/DAXX/LBH/NR1H4/UCN3/NR2F6/GHRL/TAF7/FOXH1	92
BP	GO:0016571	histone methylation	55/7096	139/18670	0.3825	0.6343	0.4729	LMNA/PHF19/CHTOP/DPY30/SETDB2/ZNF304/EZH2/PAF1/WDR5B/DOT1L/SUV39H2/TET2/PRMT9/NSD1/SETMAR/SETD5/PRDM4/SIRT1/SETD7/PAXBP1/SMYD3/BCOR/FBL/KMT2E/NTMT1/SUV39H1/ASH1L/SETD6/CTCF/SETDB1/PRMT5/COPRS/KDM4D/RNF20/PWP1/BRCA1/PRDM2/PRDM6/OGT/RLF/FBLL1/MEN1/CARM1/KMT2B/PAX7/PAX5/GCG/EZH1/PAXIP1/PRMT1/WDR82/NR1H4/WDR5/TET1/ZNF335	55
BP	GO:0046546	development of primary male sexual characteristics	55/7096	139/18670	0.3825	0.6343	0.4729	WNT5A/SRD5A1/NCOA4/FLNA/PLEKHA1/KITLG/LRRC6/NUPR1/AKR1C3/REC8/HMGCS1/UTF1/NUDT1/CTNNA1/SGPL1/ADAM15/INSR/TNFSF10/HSD17B4/EIF2S2/CCND1/CITED2/ASPM/PATZ1/BCL2L11/MGST1/BCL2/TBC1D20/BAX/HMGB2/ERCC1/INHBA/CTSV/YBX3/MMP14/RHOBTB3/HOXA10/LHFPL2/NASP/FSHR/TLR3/INHA/REN/RXFP2/WNT2B/FANCA/ZFP42/MEA1/BCL2L2/TFAP2C/CSDE1/GJA1/AMHR2/WT1/LHX9	55
BP	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	31/7096	77/18670	0.3826	0.6343	0.4729	ZFP36/TOB1/AGO2/BTG2/LSM5/SAMD4B/DCP1B/DCP2/LSM7/TNKS1BP1/DCPS/MLH1/EXOSC2/CNOT4/EDC4/TNRC6B/EXOSC7/TNRC6A/CPEB3/TTC37/POLR2D/CNOT7/ZFP36L2/EXOSC9/EXOSC3/CNOT10/SAMD4A/EXOSC6/SKIV2L/EXOSC8/EXOSC5	31
BP	GO:0031397	negative regulation of protein ubiquitination	31/7096	77/18670	0.3826	0.6343	0.4729	FYN/MAD2L2/CHP1/SMAD7/TNFAIP3/PER2/PLAA/GTPBP4/ARRB1/CDK5/ABL1/GCLC/UBR5/ISG15/GLMN/PRR7/USP4/DTX3L/IVNS1ABP/KLHL40/SPOPL/BAG2/PSEN1/UBXN1/OGT/DNAJA1/GNL3L/MTOR/SOX4/BAG5/RASD2	31
BP	GO:0045843	negative regulation of striated muscle tissue development	24/7096	59/18670	0.3827	0.6343	0.4729	DLL1/RGS2/TGFB1/PAK1/BMP2/S100B/LUC7L/SAV1/CTDP1/G6PD/BMP4/YY1/KCNK2/YBX3/PPARA/CAV3/EPHB1/MAPK11/FZD7/MEIS1/USP19/GJA1/RBP4/TLL2	24
BP	GO:0006699	bile acid biosynthetic process	15/7096	36/18670	0.3848	0.6367	0.4747	STARD4/CYP27A1/OSBPL9/SCP2/OSBPL1A/SLC27A2/HSD17B4/ACOX2/SIRT1/CH25H/OSBPL2/ABCB11/CYP46A1/NR1H4/ACOT8	15
BP	GO:0030224	monocyte differentiation	15/7096	36/18670	0.3848	0.6367	0.4747	IRF7/PIR/MYC/CD74/VEGFA/MYH9/BMP4/THOC5/DCSTAMP/CD4/CSF1R/FOXP1/HOXA7/APCS/MEF2C	15
BP	GO:0032205	negative regulation of telomere maintenance	15/7096	36/18670	0.3848	0.6367	0.4747	ERCC4/HNRNPA1/XRCC5/DCP2/NAT10/ATM/HNRNPC/XRN1/XRCC1/ERCC1/RTEL1/ACD/CTC1/GNL3L/POT1	15
BP	GO:0071634	regulation of transforming growth factor beta production	15/7096	36/18670	0.3848	0.6367	0.4747	PTGS2/HIF1A/FURIN/CREB1/ATP6AP2/TYROBP/LGALS9/CD2AP/LAPTM4B/CD34/HSP90AB1/CDH3/CX3CL1/CD24/SERPINF2	15
BP	GO:1903131	mononuclear cell differentiation	15/7096	36/18670	0.3848	0.6367	0.4747	IRF7/PIR/MYC/CD74/VEGFA/MYH9/BMP4/THOC5/DCSTAMP/CD4/CSF1R/FOXP1/HOXA7/APCS/MEF2C	15
BP	GO:2000310	regulation of NMDA receptor activity	15/7096	36/18670	0.3848	0.6367	0.4747	CRHBP/CCR2/PINK1/EPHB2/ANXA3/PTK2B/DAPK1/PPARGC1A/RASGRF1/LRRC7/IFNG/RELN/APP/GRIA2/MEF2C	15
BP	GO:0014033	neural crest cell differentiation	36/7096	90/18670	0.3862	0.6389	0.4763	HTR2B/FN1/SEMA4B/KLHL12/KITLG/RDH10/ZEB2/HIF1A/NRG1/SEMA4A/SEMA4C/SEMA4D/EFNB1/BMP7/NOLC1/SEMA6B/KBTBD8/BMPR1A/NRP1/SEMA3B/ANXA6/BMP4/NRP2/CFL1/PEF1/SEMA5A/HES1/CORO1C/SEMA5B/MAPK1/RET/PHACTR4/FBXL17/WNT10A/SMO/MEF2C	36
BP	GO:0050817	coagulation	133/7096	342/18670	0.3872	0.6404	0.4775	SH2B2/SERPINA1/SERPINB2/FYN/F5/PTPN6/PRKAR2B/CLIC1/MYL12A/LYN/IRF1/PROS1/DGKA/PLSCR1/PROCR/TFPI/HPS4/GNB1/FLNA/CD40/GNA15/PAFAH2/JAK2/CBX5/NFE2/VCL/P2RX7/A2M/CD59/PRKACB/SLC7A11/APOE/AK3/MICAL1/ENTPD1/LCP2/AXL/ACTB/DOCK8/TLN1/STXBP1/ITPR1/DGKD/ARRB1/GNAQ/HSPB1/CD36/CAPZA2/PRKCD/SRF/HBB/TSPAN32/TLR4/RAD51B/FIBP/RAP2B/DTNBP1/PLCG2/CAPZA1/TREML1/PIK3R6/P2RY12/EHD1/THBD/RAF1/RAC1/SERPING1/IL6/LCK/PDGFB/PLAUR/GNG2/MYH9/HPSE/HDAC2/P2RX1/VKORC1/MAFG/BLOC1S3/SERPINE1/PAPSS2/PRKACA/TEC/RAB5A/ITGA2/LMAN1/PLEK/PDGFA/IRF2/VWF/DMTN/F2R/BLOC1S4/NFE2L2/GGCX/C1QBP/VAV1/AP3B1/DOCK11/ANXA2P2/PSEN1/MERTK/MAPK1/GNA13/PHF21A/SLC4A1/DGKG/HPS6/HRG/CD34/EHD3/PIK3CG/F3/STXBP3/CSRP1/ANXA2/PRTN3/PRKCQ/TYRO3/HMG20B/ENPP4/P2RX2/TSPAN8/WAS/HBE1/PRKCA/RAB27A/SERPINF2/F9/GNA11/P2RY1/PIK3CB/P2RX5	133
BP	GO:0050805	negative regulation of synaptic transmission	29/7096	72/18670	0.388	0.6414	0.4781	LILRB2/RAP1B/SYT11/PTGS2/ABHD6/STXBP1/PTK2B/PNKD/SRF/PLK2/IL1B/AGER/RAP1A/LRRK2/ARC/ARF1/GNAI2/SORCS2/MTMR2/CNR2/FMR1/CBLN1/PLA2G6/SYT4/PICK1/SNCA/SLC24A2/ATAD1/SHANK3	29
BP	GO:0051881	regulation of mitochondrial membrane potential	29/7096	72/18670	0.388	0.6414	0.4781	CLIC1/PINK1/GCLM/SOD1/PMAIP1/PANK2/P2RX7/PRELID1/FZD9/ABL1/GCLC/PPA2/LRRK2/BCL2/BAX/PPP2R3C/MLLT11/NDUFS1/MUL1/SLC25A33/PID1/BAD/BCO2/OPRD1/VCP/ABCD1/BAK1/CTNS/NNT	29
BP	GO:0046661	male sex differentiation	63/7096	160/18670	0.389	0.6429	0.4793	WNT5A/SRD5A1/NCOA4/SMAD5/FLNA/PLEKHA1/KITLG/LGR4/LRRC6/NUPR1/AKR1C3/REC8/HMGCS1/UTF1/NUDT1/CTNNA1/SGPL1/ROR2/ADAM15/INSR/TNFSF10/HSD17B4/EIF2S2/CCND1/CITED2/ASPM/PATZ1/BCL2L11/BMP5/MGST1/BMPR1A/BCL2/TBC1D20/BAX/HMGB2/ERCC1/INHBA/CTSV/YBX3/MMP14/HSD17B3/RHOBTB3/HOXA10/LHFPL2/NASP/FSHR/TLR3/INHA/REN/RXFP2/GREB1L/WNT2B/ASB1/FANCA/ZFP42/MEA1/BCL2L2/TFAP2C/CSDE1/GJA1/AMHR2/WT1/LHX9	63
BP	GO:0022618	ribonucleoprotein complex assembly	108/7096	277/18670	0.3893	0.6432	0.4796	CELF6/SRSF5/C9orf72/DDX20/G3BP2/AGO2/EIF6/SRSF10/CRNKL1/RUVBL2/RUVBL1/YTHDC1/NAF1/EIF2D/COIL/EIF3M/SNRNP200/EIF4B/NPM1/SNUPN/SNRPB/GEMIN6/TXNL4A/DHX9/SRPK2/LUC7L/SFSWAP/GEMIN7/ABT1/EIF3I/EIF2S2/EIF4H/EIF2S1/CLP1/ATXN2/CD2BP2/MRTO4/LSM14A/EIF3G/PUM2/PTGES3/DDX3X/BICD1/ATM/MCTS1/SNRPD1/PRPF3/USP4/SETX/DICER1/SNRPC/RRP7A/ISY1/RPS19/ATXN2L/STRAP/TARBP2/NIP7/LUC7L2/SRSF6/SNRPF/RPF2/AGO1/DDX1/EIF3B/PRPF8/SF3A3/EIF5/GRB7/SRPK1/TICRR/WEE2-AS1/PRMT5/AAR2/POLR2D/EIF3J/TGS1/PRPF31/C1QBP/CNOT7/ATR/SART1/PRKAA1/LOC100128988/CELF2/WDR77/RPL24/EIF2A/MRPL20/NUFIP1/CLNS1A/HSP90AB1/PRPF19/CELF3/MDN1/CDC73/PRPF39/ADAR/MPV17L2/MRPS2/CPSF7/ZNHIT6/EIF3L/RPL3L/LUC7L3/RRS1/SNRPG/SNRPD2	108
BP	GO:0055002	striated muscle cell development	68/7096	173/18670	0.3895	0.6435	0.4797	IGF1/MYOF/SLC8A1/MEF2A/SKI/LMNA/RGS2/UCHL1/KLHL41/AKAP13/TMOD3/PAK1/CFL2/SRF/RYR1/PARP2/ACTC1/VEGFA/MYBPC3/DMD/AFG3L2/HOMER1/CTDP1/G6PD/SMYD3/PDLIM5/MYOG/PGM5/CAPN9/BCL2/BMP4/TPM1/NFATC2/HDAC4/YY1/OBSCN/KLHL40/KRT8/ZMPSTE24/MYOZ1/LMOD3/ALPK3/PPARA/CAV3/BIN3/HEY2/MYOM2/HAMP/SHOX2/DNER/MAP2K4/CASQ1/CAPN3/CASQ2/PIN1/SYNPO2L/GPX1/CSRP1/MTOR/P2RX2/MYH3/WNT10B/ACTA1/SMO/KEL/TNNT1/MEF2C/MYF6	68
BP	GO:0002675	positive regulation of acute inflammatory response	13/7096	31/18670	0.3901	0.6435	0.4797	PTGS2/ADAM8/TNF/FFAR2/HLA-E/IL1B/TNFRSF11A/IL6ST/IL6/C2CD4B/OSM/PIK3CG/CCR7	13
BP	GO:0002888	positive regulation of myeloid leukocyte mediated immunity	13/7096	31/18670	0.3901	0.6435	0.4797	ITGAM/DDX21/IL4R/TICAM1/STXBP1/PTAFR/DDX58/FGR/HLA-E/MAVS/ADORA2B/DDX1/SNX4	13
BP	GO:0010543	regulation of platelet activation	13/7096	31/18670	0.3901	0.6435	0.4797	LYN/APOE/PRKCD/TLR4/THBD/PDGFB/TEC/PLEK/PDGFA/DMTN/HRG/PRKCQ/PRKCA	13
BP	GO:0034694	response to prostaglandin	13/7096	31/18670	0.3901	0.6435	0.4797	PTGER4/PTGER2/GNB1/AKR1C3/P2RY6/GNG2/AKAP8/YY1/TNFSF4/PRKAA1/P2RY4/CCL19/CCR7	13
BP	GO:0040018	positive regulation of multicellular organism growth	13/7096	31/18670	0.3901	0.6435	0.4797	EZR/PLS1/CREB1/BBS2/MKKS/BBS4/BCL2/GPR21/GHRH/GHR/PPIB/SMO/GHRL	13
BP	GO:0099174	regulation of presynapse organization	13/7096	31/18670	0.3901	0.6435	0.4797	ARF6/IL1RAP/MDGA1/NTNG2/FZD1/CBLN1/EIF4G1/IL1RAPL1/GPC4/APP/SNCA/WNT7A/CLSTN3	13
BP	GO:0009798	axis specification	34/7096	85/18670	0.3915	0.6456	0.4813	DLL1/SKI/WNT5A/WLS/SMAD2/TTC8/SETDB2/LDB1/IFT172/ARL13B/SRF/ETS2/TIFAB/BASP1/CITED2/BCOR/NRARP/BMPR1A/HSPB11/BMP4/FZD5/PCSK6/HEY2/WNT1/AURKA/WNT6/WNT7A/CER1/SMO/WT1/PGAP1/PTCH1/C2CD3/CXXC4	34
BP	GO:0003143	embryonic heart tube morphogenesis	27/7096	67/18670	0.3936	0.6485	0.4834	DLL1/WNT5A/BBS5/SETDB2/IFT172/PKD2/IFT57/MIB1/HIF1A/MEGF8/ARL13B/SRF/MICAL2/MKKS/MESP1/IFT52/BBS4/BBS7/TEAD2/HES1/PSEN1/ENG/GJA1/SMO/C2CD3/MEF2C/FOXH1	27
BP	GO:1903707	negative regulation of hemopoiesis	61/7096	155/18670	0.3936	0.6485	0.4834	DLL1/ANXA1/LYN/ZFP36/IRF1/PTPN2/BCL6/LILRB3/SMAD7/CIB1/FGL2/FBXW7/MYC/IL4R/CBFB/LDB1/PAF1/CD74/NFKBIA/LILRB1/SOCS5/PTK2B/LILRB4/TLR4/ZBTB7B/DTX1/NFKBID/GPR171/HMGB1/HLA-G/KLF13/TAL1/CTLA4/NRARP/N4BP2L2/BMP4/ID2/DPF2/NME1/LAG3/INHBA/PGLYRP4/HES1/LEO1/HLX/PIAS3/NFE2L2/TNFSF4/LRRC17/SOCS1/C1QC/CLDN18/TLR3/INHA/MEIS1/TBX21/CDC73/ZBTB16/PRMT1/HOXA7/APCS	61
BP	GO:0001824	blastocyst development	39/7096	98/18670	0.394	0.6485	0.4834	IGF1/JUNB/SKIL/DAD1/CAPN2/GINS1/CCNB1IP1/ZNF830/SRF/LATS1/STMN3/ZFP14/ZPR1/PSMC4/PALB2/UBE2A/LPAR6/WDR74/BCOR/PSMC3/RRP7A/NDEL1/PHF6/ADA/COPS2/GINS4/HNF1B/RPL7L1/NASP/FBLL1/PRPF19/HS3ST6/RTN4/ACTL6A/SPIC/CMTM3/HORMAD1/TET1/TM4SF1	39
BP	GO:0099175	regulation of postsynapse organization	39/7096	98/18670	0.394	0.6485	0.4834	FYN/LILRB2/SIPA1L1/DNM3/WNT5A/ABHD17C/SLC7A11/IL1RAP/APOE/ACTR2/LRP8/UBE3A/ARF4/BAIAP2/FZD9/CDK5/ARHGAP22/PAFAH1B1/HOMER1/CAPRIN1/KALRN/LRRK2/ARC/PDLIM5/NRP2/CFL1/BHLHB9/DNM1L/CRIPT/CBLN1/IL1RAPL1/RELN/SSH1/LRP4/WNT7A/SHANK3/GHRL/ZMYND8/CAMK2B	39
BP	GO:0003254	regulation of membrane depolarization	20/7096	49/18670	0.394	0.6485	0.4834	GCLM/SMAD7/P2RX7/SCN1B/FZD9/GCLC/TRPM4/LRRK2/HCN4/BCL2/FHL1/PPP2R3C/MLLT11/RANGRF/SCN2B/CAMK2D/CAV3/ABCD1/GJA1/NTSR1	20
BP	GO:0035094	response to nicotine	20/7096	49/18670	0.394	0.6485	0.4834	TNF/SLC7A11/HMOX1/NFKB1/RELA/CASP3/CREB1/HDAC2/BCL2/CHRNG/PDX1/CHRNA4/PPARA/MAPK1/CHRNB2/BAD/MSX1/ND4/CHRNE/ATP1A2	20
BP	GO:0071825	protein-lipid complex subunit organization	20/7096	49/18670	0.394	0.6485	0.4834	APOC1/SCARB1/PLA2G7/SOAT1/PRKACB/CETP/APOE/ABCA1/ABCA5/APOA5/ARF1/LCAT/ABCG1/PRKACA/ABCA7/APOA1/SNX9/MPO/BIN1/ALB	20
BP	GO:0051302	regulation of cell division	66/7096	168/18670	0.3941	0.6485	0.4834	HTR2B/KLHL21/KLHL13/DLL1/ZFYVE26/TXNIP/NUP62/VEGFB/RAB11A/CIB1/PPBP/MYC/KIF3B/TGFB1/NCOA3/PDGFC/VEGFA/PLK2/CAT/SVIL/SFN/IL1B/RAB11FIP4/INTU/CDK2AP2/PDGFB/FGF1/FLCN/TAL1/ASPM/PROK1/BBS4/KLHL9/PLK3/PRPF40A/ORC6/KIF20B/IL1A/OSM/KIF13A/INCENP/PDGFA/EVI2B/PKN2/CETN2/SH3GLB1/TGFB3/RBL2/PIN1/C10orf99/ESRRB/PRDM15/RHOA/AURKA/ITGB1BP1/EFHC1/CSPP1/LBH/ZFYVE19/KIF14/PTCH1/E2F8/PRC1/SUSD2/PDGFD/FGF6	66
BP	GO:0031954	positive regulation of protein autophosphorylation	11/7096	26/18670	0.3957	0.6504	0.4849	GPNMB/RAP2C/PDGFC/VEGFA/RAP2B/TOM1L1/PDGFB/TNKS1BP1/PDGFA/GREM1/PDGFD	11
BP	GO:0032967	positive regulation of collagen biosynthetic process	11/7096	26/18670	0.3957	0.6504	0.4849	VIM/RGCC/TGFB1/HDAC2/BMP4/ITGA2/F2R/SUCO/TGFB3/ENG/SERPINF2	11
BP	GO:0034204	lipid translocation	11/7096	26/18670	0.3957	0.6504	0.4849	KCNN4/ATP8B2/ATP8A1/ATP11B/ATP10A/ABCA1/ATP8B1/ABCB4/ABCA7/TMEM30A/ATP10B	11
BP	GO:0048843	negative regulation of axon extension involved in axon guidance	11/7096	26/18670	0.3957	0.6504	0.4849	WNT5A/SEMA4B/SEMA4A/SEMA4C/SEMA4D/SEMA6B/NRP1/SEMA3B/SEMA5A/SEMA5B/PLXNA3	11
BP	GO:0051497	negative regulation of stress fiber assembly	11/7096	26/18670	0.3957	0.6504	0.4849	STMN1/ARAP1/S1PR1/PFN1/ARHGAP6/INPP5K/CLASP2/TACSTD2/TMEFF2/MET/WAS	11
BP	GO:0030323	respiratory tube development	69/7096	176/18670	0.3988	0.6553	0.4886	EPAS1/KLF2/ACVR2B/RBPJ/WNT5A/JMJD6/THRA/LIPA/MAP2K1/FBXW7/HECA/RDH10/SMAD2/TNF/SLC7A11/KRAS/CIC/TULP3/HEG1/SRF/CEBPA/CRISPLD2/VEGFA/CTSZ/LTBP3/HSD11B1/CREB1/SAV1/CHI3L1/FGF1/SPARC/PHF14/BMPR1A/CYP1A2/TAB1/HSPB11/AIMP2/BMP4/ADAMTS2/SRSF6/PCSK5/PDGFA/TIMELESS/ITGA3/MMP14/HES1/SPRY1/ADA/MAN1A2/PPP1CA/EGFR/ATXN1L/SPRY2/RAB3A/MAPK1/TGFB3/EIF4E/ATP7A/TBX4/TMEM38B/WNT2B/DAG1/TRAF4/FOXF1/RBP4/GRHL2/BMPR2/LAMA1/STRA6	69
BP	GO:1901862	negative regulation of muscle tissue development	25/7096	62/18670	0.3995	0.6556	0.4888	DLL1/RGS2/TGFB1/PAK1/BMP2/S100B/LUC7L/SAV1/CTDP1/G6PD/FLCN/BMP4/YY1/KCNK2/YBX3/PPARA/CAV3/EPHB1/MAPK11/FZD7/MEIS1/USP19/GJA1/RBP4/TLL2	25
BP	GO:0010463	mesenchymal cell proliferation	18/7096	44/18670	0.4002	0.6556	0.4888	WNT5A/LMNA/STAT1/MYC/DCHS1/LRP5/BMP2/VEGFA/BMP7/IRS2/PHF14/BMPR1A/BMP4/PDGFA/SHOX2/MSX1/FOXF1/SMO	18
BP	GO:0010828	positive regulation of glucose transmembrane transport	18/7096	44/18670	0.4002	0.6556	0.4888	IGF1/MEF2A/C2CD5/INSR/RAP1A/CREBL2/IRS2/ITLN1/CLTCL1/RHOQ/RNASEL/NFE2L2/ADIPOR2/NR4A3/TERT/CLIP3/APPL1/KLF15	18
BP	GO:0014003	oligodendrocyte development	18/7096	44/18670	0.4002	0.6556	0.4888	TLR2/LYN/GSTP1/TGFB1/B4GALT6/EIF2B5/HDAC11/CLU/ZNF488/HDAC10/ID2/B4GALT5/LPAR1/ERCC2/EIF2B1/EIF2B3/EIF2B2/PLP1	18
BP	GO:0033046	negative regulation of sister chromatid segregation	18/7096	44/18670	0.4002	0.6556	0.4888	DUSP1/MAD2L2/DYNC1LI1/SPDL1/NAA10/KLHL22/CDK5RAP2/ESPL1/ZNF207/LCMT1/ATM/BUB3/NDC80/GEN1/ZW10/CDC20/PCID2/IK	18
BP	GO:0098813	nuclear chromosome segregation	102/7096	262/18670	0.401	0.6556	0.4888	KLHDC8B/DUSP1/MAD2L2/NUP62/RAB11A/DYNC1LI1/FBXW7/CCNB1IP1/SPDL1/RAN/ERCC4/ACTR2/CHMP4B/PSRC1/REC8/MEI1/SMC5/SEH1L/PDS5A/LATS1/CENPE/NAA10/RMI2/KLHL22/CDK5RAP2/CCDC155/DSCC1/NSMCE2/KIF4A/SPAG5/SFPQ/MIS12/CDC23/ESPL1/ZNF207/CENPC/LCMT1/SMC2/ATM/ANAPC5/CHAMP1/NCAPD3/BUB3/PHF23/AKAP8/SPICE1/CCNE1/NDC80/MLH1/CHMP2A/CTCF/RMI1/TOP2B/DSN1/NUF2/GEN1/M1AP/NUSAP1/INCENP/ZW10/CHMP1A/VPS4B/CENPK/ACTR3/MOS/TUBG2/CDC26/STAG3/RCC2/SYCE3/RIOK2/FANCM/DLGAP5/KIF2C/SMC3/KATNB1/ANAPC4/DIS3L2/RNF212B/CDC27/CDC20/FANCD2/PCID2/RB1/STAG1/TEX15/ANKRD31/ANAPC11/STAG3L3/IK/KPNB1/MCMBP/MSTO1/CHMP1B/UBE2B/RRS1/FEN1/KIF14/BOD1/HORMAD1/PRC1/TOP2A	102
BP	GO:0002029	desensitization of G protein-coupled receptor signaling pathway	9/7096	21/18670	0.4015	0.6556	0.4888	HTR2B/ARRB1/DNM1/UBQLN2/DNM2/ADRB2/GIPR/GRK4/APLN	9
BP	GO:0003094	glomerular filtration	9/7096	21/18670	0.4015	0.6556	0.4888	PTPRO/PDGFB/SULF2/EMP2/F2R/CD34/XPNPEP3/GJA1/MCAM	9
BP	GO:0003177	pulmonary valve development	9/7096	21/18670	0.4015	0.6556	0.4888	NOTCH2/RBPJ/HEY1/BMP4/NFATC1/HEY2/SLIT2/BMPR2/STRA6	9
BP	GO:0006293	nucleotide-excision repair, preincision complex stabilization	9/7096	21/18670	0.4015	0.6556	0.4888	ERCC4/RPA1/DDB1/GTF2H4/ERCC1/DDB2/ERCC2/CUL4B/RBX1	9
BP	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion	9/7096	21/18670	0.4015	0.6556	0.4888	ERCC4/RPA1/DDB1/GTF2H4/ERCC1/DDB2/ERCC2/CUL4B/RBX1	9
BP	GO:0010893	positive regulation of steroid biosynthetic process	9/7096	21/18670	0.4015	0.6556	0.4888	POR/STARD4/TNF/IL1B/PPARGC1A/FGF1/ABCG1/PRKAA1/IFNG	9
BP	GO:0022401	negative adaptation of signaling pathway	9/7096	21/18670	0.4015	0.6556	0.4888	HTR2B/ARRB1/DNM1/UBQLN2/DNM2/ADRB2/GIPR/GRK4/APLN	9
BP	GO:0030277	maintenance of gastrointestinal epithelium	9/7096	21/18670	0.4015	0.6556	0.4888	NOD2/SLC22A5/PBLD/ZNF830/TLR4/MUC2/STRAP/MUC6/RBP4	9
BP	GO:0031498	chromatin disassembly	9/7096	21/18670	0.4015	0.6556	0.4888	MAP1S/NFE2/HMGA1/PBRM1/ARID2/SMARCC2/SET/SUPT16H/SMARCC1	9
BP	GO:0032332	positive regulation of chondrocyte differentiation	9/7096	21/18670	0.4015	0.6556	0.4888	POR/RELA/LOXL2/ANXA2P2/SOX5/ANXA2/ZBTB16/BMPR1B/GDF5	9
BP	GO:0032986	protein-DNA complex disassembly	9/7096	21/18670	0.4015	0.6556	0.4888	MYC/NFE2/HMGA1/PBRM1/ARID2/SMARCC2/SET/SUPT16H/SMARCC1	9
BP	GO:0045061	thymic T cell selection	9/7096	21/18670	0.4015	0.6556	0.4888	PTPN2/PTPRC/CD74/SRF/CD3D/CD3G/FOXN1/CCR7/CD3E	9
BP	GO:0048245	eosinophil chemotaxis	9/7096	21/18670	0.4015	0.6556	0.4888	CCL5/CCL7/CCL13/CCL8/CCL26/DAPK2/CX3CL1/CCL4/CCL24	9
BP	GO:0051412	response to corticosterone	9/7096	21/18670	0.4015	0.6556	0.4888	FOS/CDKN1A/FOSB/CCND1/NPAS4/MAOB/FOSL1/UCN3/FOXO3	9
BP	GO:0051900	regulation of mitochondrial depolarization	9/7096	21/18670	0.4015	0.6556	0.4888	GCLM/P2RX7/FZD9/GCLC/LRRK2/BCL2/PPP2R3C/MLLT11/ABCD1	9
BP	GO:0061213	positive regulation of mesonephros development	9/7096	21/18670	0.4015	0.6556	0.4888	LGR4/MAGED1/TGFB1/VEGFA/PAX8/BASP1/WNT2B/SMO/WT1	9
BP	GO:1900016	negative regulation of cytokine production involved in inflammatory response	9/7096	21/18670	0.4015	0.6556	0.4888	IL1R2/APPL2/CHID1/C5orf30/ADCY7/MEFV/PDCD4/ABCD1/NLRC3	9
BP	GO:2001014	regulation of skeletal muscle cell differentiation	9/7096	21/18670	0.4015	0.6556	0.4888	KLHL41/UQCC2/NR1D2/S100B/NLN/CYP26B1/EPHB1/ARNTL/MEF2C	9
BP	GO:0045598	regulation of fat cell differentiation	52/7096	132/18670	0.4029	0.6578	0.4904	METRNL/ZFP36/WNT5A/FNDC5/PTGS2/PPARD/DUSP10/CEBPB/TNF/ZADH2/LRP5/ANKRD26/AAMDC/TGFB1/WDFY2/LEP/SYAP1/NAPEPLD/ZBTB7B/CEBPA/BMP2/CMKLR1/MEX3C/CREB1/BBS12/SIRT1/SAV1/TRPM4/CREBL2/IL6/GNB3/TMEM64/FTO/ID2/TRIB2/ASXL2/KLF5/HES1/INSIG1/DLK2/WNT1/ZFP36L2/RORA/ARNTL/TGFB1I1/JDP2/CARM1/MTOR/TRPV4/VSTM2A/ZBTB16/WNT10B	52
BP	GO:0006119	oxidative phosphorylation	57/7096	145/18670	0.4033	0.6583	0.4908	PINK1/PGK1/UQCRC2/UQCR11/NDUFA8/NUPR1/NDUFC1/ISCU/NDUFB11/NDUFS3/NDUFA3/DNAJC30/UQCC2/NDUFA11/CHCHD10/UQCR10/COX7C/COX7A2L/NDUFA4/SHMT2/MYOG/COX4I2/NDUFA1/TEFM/COQ9/COA6/COX15/NDUFA10/NDUFB1/NDUFB5/UQCRQ/PGK2/NDUFS1/SLC25A33/NDUFB8/DNAJC15/SURF1/NDUFB6/ATP7A/NDUFB3/SDHA/VCP/NDUFS7/NDUFV2/ND4/SDHD/RHOA/TAZ/SNCA/UQCRB/ABCD1/NDUFB2/SDHAF2/COX6C/NDUFS2/NDUFA7/COX7B	57
BP	GO:0006402	mRNA catabolic process	141/7096	364/18670	0.4057	0.6601	0.4921	MYD88/ZFP36/PPP2CA/SLC11A1/VIM/PSMB9/TOB1/PSMB8/ZC3H14/NUP214/AGO2/PSMA5/PSMD11/YTHDF3/MOV10/TNPO1/HNRNPR/METTL14/GIGYF2/SECISBP2/PSME1/BTG2/RNPS1/THRAP3/PAIP1/SMG8/MAGOHB/FASTKD1/PSMB10/HSPB1/PSMA1/PSMA4/PRKCD/LSM5/METTL3/HELZ2/SAMD4B/NPM1/PSMB1/RBM8A/PSMC4/DHX9/DCP1B/RPL8/DCP2/PSMD13/ZC3H12D/PSMB3/RPS24/MRTO4/PUM2/PSMB5/LSM7/PSMD6/RPS21/ATM/GSPT2/MTPAP/TNKS1BP1/RPS9/DCPS/ZC3HAV1/PSMC3/RPS19/SCGB1A1/FTO/HNRNPC/PSME3/GTPBP1/MLH1/XRN1/MAPKAPK2/EXOSC2/PSMC6/HNRNPA0/CNOT4/EDC4/AGO1/ETF1/RNASEL/CSDC2/UBC/TNRC6B/EXOSC7/TNRC6A/HNRNPD/CPEB3/YBX3/TTC37/HNRNPM/POLR2D/TBRG4/CNOT7/SSB/FMR1/SUPV3L1/PSMC1/ZFP36L2/EIF4G1/RPL24/DXO/PSMD8/RPS16/DIS3L2/RPS12/PSMA2/EXOSC9/VIP/EXOSC3/PCID2/SET/CNOT10/RPL32/PSMC5/PSMC2/PSMB2/PSMD4/MTOR/ERN1/SAMD4A/EXOSC6/PNPT1/TIRAP/SKIV2L/EXOSC8/PSMD1/NUDT16/ROCK2/CSDE1/PSMB4/NBAS/SYNCRIP/BOLL/TARDBP/PRKCA/PSMD9/PSMD3/EXOSC5/PLEKHN1/UPF1/RPL10A	141
BP	GO:0033574	response to testosterone	16/7096	39/18670	0.4068	0.6601	0.4921	DUSP1/SRD5A1/SPP1/PSPH/CDK4/AACS/CSNK2B/SIRT1/XRN1/NME1/CALR/MSN/BAD/CAD/NASP/ROCK2	16
BP	GO:2000816	negative regulation of mitotic sister chromatid separation	16/7096	39/18670	0.4068	0.6601	0.4921	DUSP1/MAD2L2/DYNC1LI1/SPDL1/KLHL22/CDK5RAP2/ZNF207/LCMT1/ATM/BUB3/NDC80/GEN1/ZW10/CDC20/PCID2/IK	16
BP	GO:0006103	2-oxoglutarate metabolic process	7/7096	16/18670	0.4072	0.6601	0.4921	PHYH/OGDH/IDH1/ADHFE1/IDH2/GOT2/L2HGDH	7
BP	GO:0006957	complement activation, alternative pathway	7/7096	16/18670	0.4072	0.6601	0.4921	CFP/CFD/CR1/VSIG4/CFB/CFHR5/C7	7
BP	GO:0010566	regulation of ketone biosynthetic process	7/7096	16/18670	0.4072	0.6601	0.4921	EGR1/AKR1C3/BMP2/COQ3/PPARGC1A/BMP5/SIRT5	7
BP	GO:0010820	positive regulation of T cell chemotaxis	7/7096	16/18670	0.4072	0.6601	0.4921	CCR2/OXSR1/WNT5A/CXCL13/CCL5/TMEM102/ADAM17	7
BP	GO:0030252	growth hormone secretion	7/7096	16/18670	0.4072	0.6601	0.4921	ITSN1/KALRN/SERP1/LTBP4/GHRH/GHRL/KISS1	7
BP	GO:0031269	pseudopodium assembly	7/7096	16/18670	0.4072	0.6601	0.4921	CDC42EP4/KLHL41/CDC42EP2/SRGAP2C/CDC42EP3/SRGAP2/CCR7	7
BP	GO:0042448	progesterone metabolic process	7/7096	16/18670	0.4072	0.6601	0.4921	SRD5A1/EGR1/AKR1C3/DHRS9/AKR1C1/PPARGC1A/CYP46A1	7
BP	GO:0043031	negative regulation of macrophage activation	7/7096	16/18670	0.4072	0.6601	0.4921	GRN/PTPRC/LDLR/CST7/VSIG4/NR1H3/CX3CL1	7
BP	GO:0044065	regulation of respiratory system process	7/7096	16/18670	0.4072	0.6601	0.4921	TSHZ3/FTO/GLS/TLX3/ATP1A2/NLGN2/PBX3	7
BP	GO:0045986	negative regulation of smooth muscle contraction	7/7096	16/18670	0.4072	0.6601	0.4921	SOD1/PTGS2/RGS2/DOCK5/ADORA2B/ADRB2/KCNMA1	7
BP	GO:0046325	negative regulation of glucose import	7/7096	16/18670	0.4072	0.6601	0.4921	PEA15/APPL2/TNF/LEP/GRB10/PID1/STXBP3	7
BP	GO:0046519	sphingoid metabolic process	7/7096	16/18670	0.4072	0.6601	0.4921	ASAH1/SGPP2/SPTLC2/SPHK1/ACER3/KDSR/DEGS2	7
BP	GO:0051444	negative regulation of ubiquitin-protein transferase activity	7/7096	16/18670	0.4072	0.6601	0.4921	MAD2L2/SMAD7/ABL1/DTX3L/BAG2/PSEN1/BAG5	7
BP	GO:0070293	renal absorption	7/7096	16/18670	0.4072	0.6601	0.4921	AKR1C3/MAGED2/HBB/HYAL2/KCNQ1/AQP3/HNF1A	7
BP	GO:0071786	endoplasmic reticulum tubular network organization	7/7096	16/18670	0.4072	0.6601	0.4921	ARL6IP1/ATL1/RAB3GAP1/TMEM33/RTN3/ATL3/RTN4	7
BP	GO:0072224	metanephric glomerulus development	7/7096	16/18670	0.4072	0.6601	0.4921	LAMB2/LGR4/EGR1/PDGFB/RET/CD34/WT1	7
BP	GO:0072488	ammonium transmembrane transport	7/7096	16/18670	0.4072	0.6601	0.4921	SLC22A4/SLC25A20/SLC22A5/SLC12A2/SLC25A47/SLC25A45/SLC22A16	7
BP	GO:0090083	regulation of inclusion body assembly	7/7096	16/18670	0.4072	0.6601	0.4921	DNAJA4/DNAJB1/CLU/DNAJB6/PSMC5/SNCAIP/BAG5	7
BP	GO:1900242	regulation of synaptic vesicle endocytosis	7/7096	16/18670	0.4072	0.6601	0.4921	SYT11/PPP3CB/LRRK2/TOR1A/SH3GL1/DNM1/DNM1L	7
BP	GO:1902001	fatty acid transmembrane transport	7/7096	16/18670	0.4072	0.6601	0.4921	SLC25A20/CPT2/ACACB/IRS2/PRKAG2/CPT1A/THRSP	7
BP	GO:1903541	regulation of exosomal secretion	7/7096	16/18670	0.4072	0.6601	0.4921	STAM/SDCBP/CHMP2A/TSG101/HGS/VPS4B/IFNG	7
BP	GO:0060485	mesenchyme development	108/7096	278/18670	0.4077	0.6601	0.4921	HTR2B/FN1/GLIPR2/MAD2L2/RBPJ/PPP2CA/WNT5A/SEMA4B/SMAD7/KLHL12/ADIPOR1/KITLG/RDH10/STAT1/SMAD2/MYC/RGCC/DCHS1/BNC2/EZH2/PKD2/GSK3B/ZEB2/PBLD/LDLRAD4/TGFB1/HGF/HIF1A/ADAM15/HNRNPAB/NRG1/SEMA4A/LOXL2/POGLUT1/FUZ/BMP2/ACTC1/IL1B/SEMA4C/ACTA2/SDCBP/S100A4/SEMA4D/HEY1/EFNB1/BASP1/BMP7/IL6/ELL3/MESP1/CITED2/BCL9L/NOLC1/SEMA6B/AKNA/HDAC2/KBTBD8/BMP5/BMPR1A/NRP1/SEMA3B/ANXA6/STRAP/BCL2/ZNF703/BMP4/NRP2/CFL1/OLFM1/PEF1/TEAD2/SEMA5A/HES1/SPRY1/CORO1C/CLASP2/HEY2/MDM2/SEMA5B/MAPK1/EXOC4/TGFB3/SNAI1/TGFB1I1/RET/GCNT2/PHACTR4/MSX1/FOXF2/FBXL17/MTOR/HPN/RTN4/DAG1/ENG/PDCD4/WNT10A/SDHAF2/FOXF1/CER1/GREM1/ACTA1/SMO/WT1/ERBB3/MEF2C/FOXH1/BMPR2	108
BP	GO:1901879	regulation of protein depolymerization	33/7096	83/18670	0.4112	0.6601	0.4921	MAP1S/CIB1/TMOD3/LIMA1/TWF2/RDX/CFL2/CAPZA2/SWAP70/CAPG/ARHGEF2/CAPZA1/SH3BP1/SPTBN1/AVIL/CFL1/TRIOBP/ADD3/PLEK/SEMA5A/DMTN/CLASP2/LMOD3/SCIN/MAP1A/KATNB1/SPTA1/SPTBN2/NAV3/TRPV4/TTBK2/SLN/FGF13	33
BP	GO:0000050	urea cycle	5/7096	11/18670	0.4124	0.6601	0.4921	ARG2/NAGS/CEBPA/SLC25A15/NMRAL1	5
BP	GO:0000478	endonucleolytic cleavage involved in rRNA processing	5/7096	11/18670	0.4124	0.6601	0.4921	KRI1/ABT1/RPS21/RCL1/RRS1	5
BP	GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	5/7096	11/18670	0.4124	0.6601	0.4921	KRI1/ABT1/RPS21/RCL1/RRS1	5
BP	GO:0000491	small nucleolar ribonucleoprotein complex assembly	5/7096	11/18670	0.4124	0.6601	0.4921	RUVBL2/RUVBL1/NAF1/NUFIP1/ZNHIT6	5
BP	GO:0002638	negative regulation of immunoglobulin production	5/7096	11/18670	0.4124	0.6601	0.4921	TMBIM6/BCL6/CD22/PARP3/IL13RA2	5
BP	GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	5/7096	11/18670	0.4124	0.6601	0.4921	PTPN6/PTPRC/TNF/CR1/FCER2	5
BP	GO:0009125	nucleoside monophosphate catabolic process	5/7096	11/18670	0.4124	0.6601	0.4921	NUDT9/DNPH1/NUDT3/NT5M/AMPD3	5
BP	GO:0015791	polyol transport	5/7096	11/18670	0.4124	0.6601	0.4921	SLC5A3/AQP9/AQP3/PGAP1/SLC2A13	5
BP	GO:0018095	protein polyglutamylation	5/7096	11/18670	0.4124	0.6601	0.4921	TTLL4/TTLL11/TTLL1/TPGS1/TTLL6	5
BP	GO:0018202	peptidyl-histidine modification	5/7096	11/18670	0.4124	0.6601	0.4921	DPH3/DPH5/HIF1AN/DPH2/DNAJC24	5
BP	GO:0019371	cyclooxygenase pathway	5/7096	11/18670	0.4124	0.6601	0.4921	PTGS2/AKR1C3/PTGES3/HPGDS/PTGS1	5
BP	GO:0030309	poly-N-acetyllactosamine metabolic process	5/7096	11/18670	0.4124	0.6601	0.4921	B3GNT8/B3GNT2/B3GNT5/B4GALT5/B3GNT4	5
BP	GO:0031442	positive regulation of mRNA 3'-end processing	5/7096	11/18670	0.4124	0.6601	0.4921	PAF1/CPEB1/CPEB3/LEO1/CDC73	5
BP	GO:0031987	locomotion involved in locomotory behavior	5/7096	11/18670	0.4124	0.6601	0.4921	ARRDC3/PPP3CB/MYO5A/CLN6/FZD4	5
BP	GO:0032377	regulation of intracellular lipid transport	5/7096	11/18670	0.4124	0.6601	0.4921	SCP2/ARV1/NUS1/ANXA2P2/ANXA2	5
BP	GO:0032380	regulation of intracellular sterol transport	5/7096	11/18670	0.4124	0.6601	0.4921	SCP2/ARV1/NUS1/ANXA2P2/ANXA2	5
BP	GO:0032383	regulation of intracellular cholesterol transport	5/7096	11/18670	0.4124	0.6601	0.4921	SCP2/ARV1/NUS1/ANXA2P2/ANXA2	5
BP	GO:0033629	negative regulation of cell adhesion mediated by integrin	5/7096	11/18670	0.4124	0.6601	0.4921	CYP1B1/SWAP70/MUC1/SERPINE1/HRG	5
BP	GO:0033860	regulation of NAD(P)H oxidase activity	5/7096	11/18670	0.4124	0.6601	0.4921	GNAI3/RFK/GNAI2/CYBA/SLAMF8	5
BP	GO:0035246	peptidyl-arginine N-methylation	5/7096	11/18670	0.4124	0.6601	0.4921	PRMT9/NDUFAF7/PRMT5/CARM1/PRMT1	5
BP	GO:0035542	regulation of SNARE complex assembly	5/7096	11/18670	0.4124	0.6601	0.4921	VPS41/STXBP1/ANKRD27/VPS18/VPS16	5
BP	GO:0035739	CD4-positive, alpha-beta T cell proliferation	5/7096	11/18670	0.4124	0.6601	0.4921	CD55/ARG2/CD274/LGALS9/TWSG1	5
BP	GO:0035747	natural killer cell chemotaxis	5/7096	11/18670	0.4124	0.6601	0.4921	CCL5/CCL7/PIK3CD/PIK3CG/CCL4	5
BP	GO:0036444	calcium import into the mitochondrion	5/7096	11/18670	0.4124	0.6601	0.4921	MCU/AFG3L2/PSEN2/MICU1/MICU2	5
BP	GO:0036462	TRAIL-activated apoptotic signaling pathway	5/7096	11/18670	0.4124	0.6601	0.4921	TNFRSF10A/TNFRSF10C/CASP8/TNFRSF10B/FADD	5
BP	GO:0043117	positive regulation of vascular permeability	5/7096	11/18670	0.4124	0.6601	0.4921	TGFB1/VEGFA/CXCR2/TRPV4/TACR2	5
BP	GO:0044793	negative regulation by host of viral process	5/7096	11/18670	0.4124	0.6601	0.4921	PTX3/CCL8/CCNK/EIF2AK4/APCS	5
BP	GO:0045176	apical protein localization	5/7096	11/18670	0.4124	0.6601	0.4921	RDX/ARF4/GOPC/NAPA/HCN1	5
BP	GO:0046007	negative regulation of activated T cell proliferation	5/7096	11/18670	0.4124	0.6601	0.4921	CASP3/PDCD1LG2/CD274/LGALS9/BTN2A2	5
BP	GO:0046051	UTP metabolic process	5/7096	11/18670	0.4124	0.6601	0.4921	AK3/NME3/NME4/NME1/CAD	5
BP	GO:0046348	amino sugar catabolic process	5/7096	11/18670	0.4124	0.6601	0.4921	GNPDA1/NPL/NAGK/RENBP/CTBS	5
BP	GO:0048672	positive regulation of collateral sprouting	5/7096	11/18670	0.4124	0.6601	0.4921	SEMA4D/LRP1/LPAR3/IST1/CRABP2	5
BP	GO:0051791	medium-chain fatty acid metabolic process	5/7096	11/18670	0.4124	0.6601	0.4921	ACOT7/OXSM/ACADM/ABHD3/CROT	5
BP	GO:0055091	phospholipid homeostasis	5/7096	11/18670	0.4124	0.6601	0.4921	CETP/ABCA1/FABP3/ABCG1/APOA1	5
BP	GO:0060856	establishment of blood-brain barrier	5/7096	11/18670	0.4124	0.6601	0.4921	LSR/MFSD2A/MXRA8/ENG/WNT7A	5
BP	GO:0061314	Notch signaling involved in heart development	5/7096	11/18670	0.4124	0.6601	0.4921	NOTCH2/RBPJ/HEY1/HEY2/SNAI1	5
BP	GO:0070269	pyroptosis	5/7096	11/18670	0.4124	0.6601	0.4921	AIM2/APIP/DHX9/NLRP9/GSDMC	5
BP	GO:0072537	fibroblast activation	5/7096	11/18670	0.4124	0.6601	0.4921	GCLM/IL17RA/RGCC/LEP/GCLC	5
BP	GO:0072584	caveolin-mediated endocytosis	5/7096	11/18670	0.4124	0.6601	0.4921	PACSIN2/ITSN1/MLC1/CAV3/MAPK1	5
BP	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	5/7096	11/18670	0.4124	0.6601	0.4921	USP46/OPHN1/NUMB/ARC/GSG1L	5
BP	GO:1901660	calcium ion export	5/7096	11/18670	0.4124	0.6601	0.4921	ATP2B4/SLC35G1/LETM1/YWHAE/SLC8A3	5
BP	GO:1902805	positive regulation of synaptic vesicle transport	5/7096	11/18670	0.4124	0.6601	0.4921	UNC13B/CDK5/DNM1L/SYT9/SYT1	5
BP	GO:1903299	regulation of hexokinase activity	5/7096	11/18670	0.4124	0.6601	0.4921	COX11/DUSP12/PFKFB1/PFKFB2/BAD	5
BP	GO:1903980	positive regulation of microglial cell activation	5/7096	11/18670	0.4124	0.6601	0.4921	CTSC/MIR142/TTBK1/LRRK2/TREM2	5
BP	GO:1905146	lysosomal protein catabolic process	5/7096	11/18670	0.4124	0.6601	0.4921	LAMP2/LDLR/LRP1/MGAT3/LAPTM4B	5
BP	GO:1905214	regulation of RNA binding	5/7096	11/18670	0.4124	0.6601	0.4921	CDK9/FMR1/EIF4G1/CARM1/NUCKS1	5
BP	GO:1905383	protein localization to presynapse	5/7096	11/18670	0.4124	0.6601	0.4921	HSPB1/DVL1/MAP1A/KIF5B/WNT7A	5
BP	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	5/7096	11/18670	0.4124	0.6601	0.4921	CEBPB/ATF4/HSPA5/MBTPS2/ATF6B	5
BP	GO:2000551	regulation of T-helper 2 cell cytokine production	5/7096	11/18670	0.4124	0.6601	0.4921	NLRP3/RSAD2/IL6/PRKCZ/TBX21	5
BP	GO:2000561	regulation of CD4-positive, alpha-beta T cell proliferation	5/7096	11/18670	0.4124	0.6601	0.4921	CD55/ARG2/CD274/LGALS9/TWSG1	5
BP	GO:0006301	postreplication repair	21/7096	52/18670	0.4125	0.6601	0.4921	MAD2L2/UBE2N/RPA1/ZBTB1/UBE2L6/POLD4/POLD2/ISG15/UBE2A/POLI/RFC3/POLH/NPLOC4/PCNA/UBC/DTL/BRCA1/USP10/POLD1/VCP/UBE2B	21
BP	GO:0050885	neuromuscular process controlling balance	21/7096	52/18670	0.4125	0.6601	0.4921	HEXB/CAMTA1/TPP1/GM2A/PSAP/GIGYF2/CLN8/ABR/ABL1/PAFAH1B1/CLN3/TIFAB/BCR/SHANK1/GRIN2C/BLOC1S4/POU4F3/GAA/NR4A3/APP/NLGN2	21
BP	GO:1902373	negative regulation of mRNA catabolic process	21/7096	52/18670	0.4125	0.6601	0.4921	MYD88/ZFP36/SLC11A1/TOB1/SECISBP2/THRAP3/PAIP1/DHX9/HNRNPC/MAPKAPK2/HNRNPA0/HNRNPD/YBX3/FMR1/VIP/MTOR/TIRAP/NBAS/SYNCRIP/BOLL/TARDBP	21
BP	GO:0035148	tube formation	58/7096	148/18670	0.4135	0.6615	0.4932	VASP/BCL10/SKI/WNT5A/TSC1/TCTN1/IFT172/DVL2/PRKACB/IFT57/ZEB2/PLXNB2/MIB1/TGFB1/TULP3/PFN1/HIF1A/TRAF6/FUZ/VEGFA/CASP3/ABL1/PAX8/SEMA4C/BMP7/IFT52/GLMN/BBS4/EDA/DICER1/BCL2L11/BMP5/EDAR/BMP4/TGM2/KDM2B/BCAS3/KIF20B/CFL1/PRKACA/SPINT1/MKS1/TEAD2/FZD1/DVL1/KAT2A/CTHRC1/HNF1B/RET/PHACTR4/IRX1/WNT6/ITGB1BP1/FZD2/SOX4/GRHL3/PTCH1/GRHL2	58
BP	GO:0060359	response to ammonium ion	53/7096	135/18670	0.4136	0.6615	0.4932	CRHBP/PEA15/ATP2B4/ATG7/FOSB/DIAPH1/GNB1/GNA15/CASP6/HNMT/ATF4/RELA/UBE3A/SIN3A/PTAFR/MAP1LC3A/GNAQ/PTK2B/MBD1/HSPA5/CDK5/CASP3/ABL1/AIF1/CASP7/HOMER1/LRRK2/HDAC2/DNM2/GNAI2/HNRNPD/PITX3/GOT2/ADA/CHRM2/CHRNA4/PLCB1/FADD/DNMT3A/MDM2/MAPK1/CHRNB2/SRR/SMPD1/HSP90AB1/CCNA2/MTOR/HDAC5/SNCA/ROCK2/EFTUD2/GNA11/HTR3A	53
BP	GO:0036474	cell death in response to hydrogen peroxide	14/7096	34/18670	0.414	0.662	0.4935	PINK1/PSAP/HGF/LRRK2/MIR34A/NFE2L2/TXN/NR4A3/PDE8A/PDCD10/SIGMAR1/MET/ENDOG/FOXO3	14
BP	GO:0051148	negative regulation of muscle cell differentiation	26/7096	65/18670	0.4156	0.6643	0.4953	DLL1/RGS2/EZH2/CXCL10/NFATC3/PAK1/BMP2/MED28/CTDP1/PDGFB/G6PD/NFATC1/ANKRD17/NFATC2/HDAC4/YY1/FOXO4/PPARA/CAV3/HEY2/PRDM6/FZD7/MSX1/HDAC5/PDCD4/TMEM119	26
BP	GO:0051187	cofactor catabolic process	26/7096	65/18670	0.4156	0.6643	0.4953	BLVRB/AHCY/ACOT7/HMOX1/PRDX1/HBB/CAT/GPX3/CBR3/PRDX6/HBQ1/AMBP/NUDT7/GGT7/GGT5/HP/ALDH1L1/CHAC2/GPX1/VCP/SNCA/ABCD1/GGTLC1/HBE1/MPO/NNT	26
BP	GO:0031016	pancreas development	31/7096	78/18670	0.4175	0.6671	0.4973	DLL1/ANXA1/ACVR2B/WNT5A/WLS/SMAD2/GSK3B/WFS1/INSR/RFX3/IL6/BMP5/BMP4/PDX1/HES1/CLOCK/GIPR/TCF7L2/BAD/HNF1B/HNF1A/ARNTL/MEN1/SOX4/MET/SIDT2/BAK1/MSLN/FOXF1/PAX4/SMO	31
BP	GO:0038095	Fc-epsilon receptor signaling pathway	66/7096	169/18670	0.4177	0.6674	0.4975	FOS/BCL10/LYN/PSMB9/CUL1/PSMB8/PSMA5/PSMD11/NFKB1/PSME1/LCP2/RELA/PPP3CB/NFATC3/LAT2/PAK1/PSMB10/PSMA1/PSMA4/TAB3/TRAF6/IKBKG/PSMB1/PAK2/PSMC4/PLCG2/SHC1/PSMD13/PSMB3/RAC1/ITK/PSMB5/PSMD6/PSMC3/FCER1A/MAPK8/TAB1/PSME3/NFATC1/PSMC6/NFATC2/TEC/GRB2/FER/VAV1/MAPK1/PSMC1/MAP2K4/PSMD8/PSMA2/NR4A3/MAP3K1/PSMC5/PSMC2/PSMB2/PSMD4/PRKCQ/MALT1/CHUK/PSMD1/PSMB4/PSMD9/PSMD3/LAT/PIK3CB/MAPK9	66
BP	GO:0006638	neutral lipid metabolic process	51/7096	130/18670	0.419	0.669	0.4988	SLC27A1/SLC22A4/FABP4/DGKA/GPAM/ABHD6/PANK2/FBXW7/ABHD12/SIK1/ATG14/APOC1/GK/SCARB1/MGLL/CETP/APOE/PNPLA3/DGKD/PCK2/NR1H2/ACSL4/CAT/LDLR/LMF1/APOBR/SIRT1/DGAT2/FABP3/GNB3/APOA5/DAGLB/GK5/NR1H3/PNPLA5/CPT1A/SERPINA12/INSIG1/FABP5/CAV3/AGPAT5/APOA1/DGKG/PIK3CG/GPX1/SNCA/ABHD16A/PGS1/THRSP/G6PC/PNPLA4	51
BP	GO:0006997	nucleus organization	51/7096	130/18670	0.419	0.669	0.4988	SUN2/PPP2CA/LMNA/GOLM1/AGFG1/TMEM43/CHMP4B/SYCP3/SEH1L/HABP4/UBXN2B/PAFAH1B1/EMD/ZPR1/NSFL1C/SRPK2/PML/ATXN7/TOR1B/NOLC1/ANKLE2/SUMO1/ETS1/BANF1/TOR1A/RPS19/CHMP2A/HMGB2/NUP107/NDEL1/USPL1/CHMP1A/SRPK1/VPS4B/ZMPSTE24/DYRK3/NFE2L1/NUP93/TBPL1/NUP205/VRK1/SPAG4/PARP11/LEMD3/REEP3/CELF3/RTN4/CHMP1B/TARDBP/PRKCA/BIN1	51
BP	GO:0048806	genitalia development	19/7096	47/18670	0.4196	0.6697	0.4993	WNT5A/SRD5A1/LGR4/AXL/ROR2/DNAJC19/TIFAB/BMP5/BAX/MERTK/HSD17B3/GREB1L/FOXF2/ASB1/TYRO3/BAK1/WT1/RBP4/STRA6	19
BP	GO:1903115	regulation of actin filament-based movement	19/7096	47/18670	0.4196	0.6697	0.4993	ATP1A1/FLNA/KCNE3/PDE4B/MYBPC3/TRPM4/SUMO1/SRI/CTNNA3/HCN4/RANGRF/CAMK2D/DSC2/CAV3/ATP2A2/PKP2/FGF13/ATP1A2/BIN1	19
CC	GO:0010008	endosome membrane	254/7377	479/19717	1.523e-12	8.922e-10	6.382e-10	MYD88/FCGR1B/ATP6V0D2/SLC48A1/STAM/CYB561A3/ANXA1/SUN2/STX7/APPL2/ARF6/SNX1/SLC29A3/IRF7/FCGR1A/SLC11A1/SLC9A9/APH1B/MCOLN1/GPNMB/ATP6AP1/TPCN1/CTSD/ECE1/GGA2/STEAP4/WDR91/RAB11A/MMD/PACSIN2/CD1C/ABHD6/SNX10/PLIN3/WLS/LY96/OSBPL9/WDR81/LAMP2/ABHD17C/LAMP3/LAMP1/ATP6V0C/PSENEN/CD320/PDIA3/PLEKHM2/VPS37B/IFITM3/RAB31/SCAMP2/TICAM1/PLD1/TBC1D5/VPS41/ITM2B/CHMP4B/LDLRAD4/IRAK4/RAB23/GRIPAP1/ZFYVE28/STEAP3/NCF4/UBE2D3/INSR/TAB3/WDR83/RAP2C/HLA-F/MICALL1/CD63/PRAF2/TRAF6/CMTM6/PLEKHB2/SPPL2A/NAPEPLD/SNX20/TCIRG1/ATP11B/ABCB6/SNX18/TLR4/RNF13/HLA-DPB1/HLA-DPA1/HLA-E/HLA-B/FIG4/VAMP3/EHD4/CLCN3/SCAMP1/PMEPA1/RAP2B/DTNBP1/LAMTOR1/FURIN/TOM1L1/VPS33A/RAB11FIP4/VPS37C/LDLR/VTA1/TMEM9/CD1B/STARD3NL/PML/HLA-DMB/WIPI1/EHD1/RAB8A/TMEM106B/HLA-DOB/HLA-G/RAC1/NDRG1/PLEKHM1/ABCA5/OCRL/GOSR2/AP5S1/HLA-DRA/AP1G2/EPHA8/GNPNAT1/CLVS2/ARC/SNX27/SLC9A7/HLA-DMA/HLA-C/KIF16B/SNX6/ATG9A/DTX3L/SPHK1/SH3GL1/TM9SF2/PARM1/ARL8A/GPR62/SCAMP4/AP2A2/LAMTOR4/TAB1/ANXA6/VPS18/MTMR4/ATP6V0E2/RAB5C/CHMP2A/TSG101/SORCS2/RAB5A/ADRB2/UBAP1/ACAP1/SNX13/HGS/AP2S1/CD1D/MTMR2/RHOV/UBC/CD1A/KIF13A/INPP5F/CD274/VPS52/RFFL/VTI1A/CHMP1A/VPS4B/RABGEF1/FZD5/RAB7B/MCOLN2/CPTP/CORO1C/AP2A1/ABCA7/LAMTOR5/VPS25/COMMD1/LAPTM4B/RAB8B/RABEP1/EGFR/KIR2DL4/RCC2/LTV1/TFRC/RAB22A/PSEN1/TLR8/ANTXR2/DCSTAMP/VPS29/CLCN4/HLA-DQB2/SNX5/RAB35/STX12/ZDHHC2/GPR61/AP5M1/VTI1B/HLA-A/SNX21/UBAP1L/HPS6/EPHB1/LLGL1/SNX19/STX8/RET/EHD3/MMGT1/CLEC16A/TLR3/FZD7/SNX4/VPS16/OPTN/SLA2/AP2M1/SYT5/MREG/ANXA2/SCAMP5/SBF2/RABEPK/VAC14/ACAP2/CLIP3/PDLIM4/SLC9B2/OCA2/APH1A/CLCN5/CHMP1B/MCOLN3/SNX16/UBA1/APPL1/RAB27A/SLC38A9/HLA-DOA/ZNRF2/ARL8B/NTRK2/SNX17	254
CC	GO:0101002	ficolin-1-rich granule	116/7377	185/19717	2.305e-12	8.922e-10	6.382e-10	SERPINA1/FPR2/FPR1/ALOX5/PNP/ASAH1/HK3/QPCT/LILRB2/LILRA3/ATG7/CD55/SLC11A1/CLEC4D/HSPA6/MNDA/CD58/MGAM/DIAPH1/CTSD/FCN1/TIMP2/MIF/DYNC1LI1/CTSS/FGL2/CD93/LAMP2/SLC2A3/GSTP1/VCL/PSMA5/ADAM8/LAMP1/PSMD11/ATP6V0C/AGL/CST3/ACTR2/FCAR/COMMD3/PGAM1/PKM/ARSB/ALAD/TNFAIP6/HBB/GMFG/CFD/ALDOC/TCIRG1/NBEAL2/IMPDH1/GNS/CRISPLD2/CAT/ACLY/CTSZ/PSMB1/ALDOA/LAMTOR1/MVP/CTSB/PSMD13/CSNK2B/HMGB1/ATP6AP2/IDH1/PRG2/TRPM2/GPI/RAC1/CR1/ILF2/BIN2/DDX3X/PSMD6/GUSB/PSMC3/PGM2/ARL8A/AP2A2/MMP9/COTL1/YPEL5/CAND1/LRG1/KCMF1/DERA/CD300A/SRP14/PTPRN2/OSTF1/A1BG/CCT8/MAPK1/COMMD9/APEH/PDAP1/XRCC6/GAA/PSMA2/TBC1D10C/HSP90AB1/PYGL/SERPINB6/PSMC2/CDA/VCP/RHOA/ENPP4/AMPD3/KPNB1/SERPINB10/PFKL/PSMD3	116
CC	GO:0031983	vesicle lumen	189/7377	339/19717	3.761e-12	9.692e-10	6.933e-10	FUCA1/IGF1/S100A9/S100A8/SERPINA1/S100A12/ALOX5/PNP/FN1/F5/HK3/QPCT/PTPN6/HEXB/RNASE2/VAT1/GRN/ATG7/CTSA/ARMC8/AZU1/RETN/GHDC/HSPA6/MNDA/PROS1/VEGFB/CTSD/FCN1/GM2A/CDC37L1/NPC2/TIMP2/CREG1/PLAC8/ACAA1/MIF/ACTN4/CTSC/PPBP/GSTP1/VCL/A2M/PSMA5/PSMD11/S100P/S100A11/NFKB1/APOE/AGL/ACTR2/STK11IP/PGAM1/PKM/TGFB1/SCCPDH/ARSB/ALAD/RNASE3/HGF/MAGED2/FTL/MAN2B1/PRKCD/CFP/HBB/SERPINB1/ACTN1/FAM49B/OSCAR/GMFG/GCA/PTX3/CFD/ALDOC/FGR/IMPDH1/QSOX1/CAP1/GNS/CRISPLD2/VEGFA/CAT/ACLY/CTSZ/PSMB1/TEX264/ALDOA/MVP/XRCC5/GDI2/SDCBP/ERP44/PSMD13/CSNK2B/HMGB1/IDH1/AGA/CLU/GPI/CHI3L1/GLA/SERPING1/PCYOX1L/PDGFB/NHLRC3/CYFIP1/ILF2/BIN2/DDX3X/SPARC/PSMD6/SCG3/GUSB/CNN2/PSMC3/PGM2/HPSE/SCGB3A2/COTL1/CAND1/SERPINE1/TIMP1/LRG1/PRDX6/TOLLIP/UNC13D/DERA/DSN1/IST1/SRP14/PDGFA/FRK/CYB5R3/VWF/NHLRC2/ADA/OSTF1/CALR/A1BG/CCT8/FABP5/EGFR/HSP90B1/ARSA/LRRC7/SRGN/MAPK1/COMMD9/APOA1/TCN1/VTI1B/XRCC6/TGFB3/FUCA2/CTSW/PSMA2/NEU1/HRG/GNLY/HP/HYOU1/HSP90AB1/CTSG/DBH/TOR4A/C6orf120/PYGL/PSMC2/CDA/VCP/ANXA2/PRTN3/APP/AMPD3/KPNB1/GCG/PSMD1/PFKL/APOOL/MPO/RAB27A/SERPINF2/PA2G4/PSMD3/ITIH3/PRSS2/GHRL/ALB	189
CC	GO:0060205	cytoplasmic vesicle lumen	188/7377	338/19717	5.678e-12	9.692e-10	6.933e-10	FUCA1/IGF1/S100A9/S100A8/SERPINA1/S100A12/ALOX5/PNP/FN1/F5/HK3/QPCT/PTPN6/HEXB/RNASE2/VAT1/GRN/ATG7/CTSA/ARMC8/AZU1/RETN/GHDC/HSPA6/MNDA/PROS1/VEGFB/CTSD/FCN1/GM2A/CDC37L1/NPC2/TIMP2/CREG1/PLAC8/ACAA1/MIF/ACTN4/CTSC/PPBP/GSTP1/VCL/A2M/PSMA5/PSMD11/S100P/S100A11/NFKB1/APOE/AGL/ACTR2/STK11IP/PGAM1/PKM/TGFB1/SCCPDH/ARSB/ALAD/RNASE3/HGF/MAGED2/FTL/MAN2B1/PRKCD/CFP/HBB/SERPINB1/ACTN1/FAM49B/OSCAR/GMFG/GCA/PTX3/CFD/ALDOC/FGR/IMPDH1/QSOX1/CAP1/GNS/CRISPLD2/VEGFA/CAT/ACLY/CTSZ/PSMB1/TEX264/ALDOA/MVP/XRCC5/GDI2/SDCBP/ERP44/PSMD13/CSNK2B/HMGB1/IDH1/AGA/CLU/GPI/CHI3L1/GLA/SERPING1/PCYOX1L/PDGFB/NHLRC3/CYFIP1/ILF2/BIN2/DDX3X/SPARC/PSMD6/SCG3/GUSB/CNN2/PSMC3/PGM2/HPSE/SCGB3A2/COTL1/CAND1/SERPINE1/TIMP1/LRG1/PRDX6/TOLLIP/UNC13D/DERA/DSN1/IST1/SRP14/PDGFA/FRK/CYB5R3/VWF/NHLRC2/ADA/OSTF1/CALR/A1BG/CCT8/FABP5/HSP90B1/ARSA/LRRC7/SRGN/MAPK1/COMMD9/APOA1/TCN1/VTI1B/XRCC6/TGFB3/FUCA2/CTSW/PSMA2/NEU1/HRG/GNLY/HP/HYOU1/HSP90AB1/CTSG/DBH/TOR4A/C6orf120/PYGL/PSMC2/CDA/VCP/ANXA2/PRTN3/APP/AMPD3/KPNB1/GCG/PSMD1/PFKL/APOOL/MPO/RAB27A/SERPINF2/PA2G4/PSMD3/ITIH3/PRSS2/GHRL/ALB	188
CC	GO:0034774	secretory granule lumen	180/7377	321/19717	6.261e-12	9.692e-10	6.933e-10	FUCA1/IGF1/S100A9/S100A8/SERPINA1/S100A12/ALOX5/PNP/FN1/F5/HK3/QPCT/PTPN6/HEXB/RNASE2/VAT1/GRN/ATG7/CTSA/ARMC8/AZU1/RETN/GHDC/HSPA6/MNDA/PROS1/VEGFB/CTSD/FCN1/GM2A/CDC37L1/NPC2/TIMP2/CREG1/PLAC8/ACAA1/MIF/ACTN4/CTSC/PPBP/GSTP1/VCL/A2M/PSMA5/PSMD11/S100P/S100A11/NFKB1/AGL/ACTR2/STK11IP/PGAM1/PKM/TGFB1/SCCPDH/ARSB/ALAD/RNASE3/HGF/MAGED2/FTL/MAN2B1/PRKCD/CFP/SERPINB1/ACTN1/FAM49B/OSCAR/GMFG/GCA/PTX3/CFD/ALDOC/FGR/IMPDH1/QSOX1/CAP1/GNS/CRISPLD2/VEGFA/CAT/ACLY/CTSZ/PSMB1/TEX264/ALDOA/MVP/XRCC5/GDI2/SDCBP/ERP44/PSMD13/CSNK2B/HMGB1/IDH1/AGA/CLU/GPI/CHI3L1/GLA/SERPING1/PCYOX1L/PDGFB/NHLRC3/CYFIP1/ILF2/BIN2/DDX3X/SPARC/PSMD6/SCG3/GUSB/CNN2/PSMC3/PGM2/HPSE/COTL1/CAND1/SERPINE1/TIMP1/LRG1/PRDX6/TOLLIP/UNC13D/DERA/DSN1/IST1/SRP14/PDGFA/FRK/CYB5R3/VWF/NHLRC2/OSTF1/A1BG/CCT8/FABP5/ARSA/LRRC7/SRGN/MAPK1/COMMD9/APOA1/TCN1/VTI1B/XRCC6/TGFB3/FUCA2/CTSW/PSMA2/NEU1/HRG/HP/HSP90AB1/CTSG/DBH/TOR4A/C6orf120/PYGL/PSMC2/CDA/VCP/ANXA2/PRTN3/APP/AMPD3/KPNB1/GCG/PSMD1/PFKL/APOOL/MPO/RAB27A/SERPINF2/PA2G4/PSMD3/ITIH3/PRSS2/GHRL/ALB	180
CC	GO:0005765	lysosomal membrane	193/7377	354/19717	3.235e-11	4.174e-09	2.986e-09	ATP6V0D2/SLC48A1/FPR1/CYB561A3/ZFYVE26/STX7/GRN/SLC29A3/CTSA/AZU1/MCOLN1/SLC36A1/MANBA/DRAM2/SLC35F6/RAP1B/ATP8A1/BLOC1S2/TPCN1/CTSD/ECE1/GNAI3/CKAP4/GNB1/ATP6V1C1/MMD/GNB2/AP1B1/ABHD6/ACPP/ABCD4/ATRAID/FLOT1/CLCN7/WDR81/LAMP2/SCARB1/TRIM23/SLC2A6/LAMP3/PSAP/LAMP1/CD74/SPNS1/ATP6V0C/IFITM3/SLC26A11/GPR137B/TMEM192/PLD1/DPP4/M6PR/VPS41/STK11IP/SLC2A8/WDR24/CYBRD1/AP5B1/ARRB1/GNAQ/SEH1L/SLCO4C1/HLA-F/CD63/WDR11/CMTM6/SPPL2A/TCIRG1/ATP11B/AHNAK/PNPLA7/CCZ1B/RNF13/HLA-DPB1/HLA-DPA1/GOPC/ATP6V1A/IGF2R/LAMTOR1/CLN3/VPS33A/LDLR/TMEM9/CD1B/STARD3NL/HLA-DMB/LRP1/NPRL3/TRPM2/TMEM106B/HLA-DOB/PLEKHM1/ATP6V1B2/ABCA5/KPTN/AP5S1/HLA-DRA/AP1M2/OSTM1/HLA-DMA/ATP6V1D/DTX3L/C3AR1/DAGLB/HPSE/VNN1/GDAP2/ARL8A/MGST1/AP2A2/LAMTOR4/TMEM63A/ANXA6/VPS18/TOM1/RAB5C/MFSD8/PI4K2A/AP2S1/CD1D/GPR143/CLN5/GNB4/BRI3/RRAGA/SLC17A5/NAPG/AP2A1/LMBRD1/BLOC1S1/GLIPR1/EEF1A2/LAMTOR5/LAPTM4B/AP1S3/ITFG2/AP3B1/ABCC10/SLC15A3/NFAM1/CPNE1/AP1G1/PSEN1/TLR8/CCZ1/HLA-DQB2/NPRL2/CYB561/AP5M1/VTI1B/GAA/HPS6/EVA1A/TMEM79/NEU1/SLC30A2/CPNE3/AP3M1/AP1M1/STX8/SLC44A2/TMEM30A/HSP90AB1/CLEC16A/TLR3/VPS16/SNAP29/AP2M1/MREG/ANXA2/MTOR/TSPAN1/RAB3D/B4GALT1/DEPDC5/OCA2/ABCD1/LPCAT1/TM6SF1/SIDT2/SLC12A4/CEACAM8/DRAM1/CLCN5/MCOLN3/UBA1/CTNS/DDOST/GNA11/SLC38A9/HLA-DOA/ZNRF2/ARL8B	193
CC	GO:0005774	vacuolar membrane	219/7377	412/19717	3.912e-11	4.326e-09	3.094e-09	ATP6V0D2/SLC48A1/FPR1/CYB561A3/ZFYVE26/TMEM138/STX7/GRN/SLC29A3/CTSA/AZU1/MCOLN1/SLC36A1/MANBA/DRAM2/SLC35F6/RAP1B/ATP8A1/BLOC1S2/TPCN1/CTSD/ECE1/GNAI3/CKAP4/GNB1/ATP6V1C1/MMD/GNB2/AP1B1/ABHD6/ACPP/ABCD4/ATRAID/FLOT1/ATG14/CLCN7/WDR81/LAMP2/SCARB1/TRIM23/SLC2A6/LAMP3/PSAP/LAMP1/CD74/SPNS1/ATP6V0C/IFITM3/SLC26A11/GPR137B/TMEM192/PLD1/DPP4/M6PR/VPS41/STK11IP/SLC2A8/WDR24/CYBRD1/AP5B1/ARRB1/MAP1LC3A/GNAQ/SEH1L/MAN2B1/SLCO4C1/HLA-F/CD63/WDR11/CMTM6/SPPL2A/TCIRG1/ATP11B/AHNAK/ABCB6/PNPLA7/CCZ1B/RNF13/HLA-DPB1/HLA-DPA1/GOPC/ATP6V1A/IGF2R/TEX264/LAMTOR1/CLN3/VPS33A/LDLR/TMEM9/CD1B/STARD3NL/RRAGD/HLA-DMB/LRP1/WIPI1/NPRL3/THBD/ATP6V1G3/TRPM2/TMEM106B/HLA-DOB/PLEKHM1/ATP6V1B2/ABCA5/KPTN/AP5S1/HLA-DRA/AP1M2/MAP1LC3C/OSTM1/HLA-DMA/ATP6V1D/RPN2/DTX3L/C3AR1/DAGLB/HPSE/VNN1/GDAP2/ARL8A/MGST1/AP2A2/LAMTOR4/TMEM63A/ANXA6/VPS18/NAPA/TOM1/RAB5C/MFSD8/PI4K2A/AP2S1/CD1D/MTMR2/GPR143/CLN5/RAB7B/GNB4/BRI3/ATP6V1G2/RRAGA/SLC17A5/NAPG/AP2A1/LMBRD1/BLOC1S1/GLIPR1/EEF1A2/LAMTOR5/LAPTM4B/ULK1/AP1S3/ITFG2/AP3B1/ABCC10/LTV1/SLC15A3/NFAM1/CPNE1/AP1G1/PSEN1/TLR8/CCZ1/HLA-DQB2/SH3GLB1/NPRL2/CYB561/AP5M1/VTI1B/GAA/ATG16L2/HPS6/EVA1A/TMEM79/NEU1/SLC30A2/CPNE3/AP3M1/AP1M1/STX8/SLC44A2/TMEM30A/GABARAPL1/HSP90AB1/CLEC16A/TLR3/VPS16/ABCC3/SNAP29/AP2M1/MREG/ANXA2/MTOR/TSPAN1/SBF2/RAB3D/VAC14/B4GALT1/DEPDC5/ATP6V1B1/OCA2/ABCD1/LPCAT1/TM6SF1/SIDT2/SLC12A4/CEACAM8/DRAM1/CLCN5/MAN2B2/MCOLN3/UBA1/CTNS/DDOST/GNA11/SLC38A9/HLA-DOA/ZNRF2/ARL8B	219
CC	GO:0098852	lytic vacuole membrane	193/7377	355/19717	4.486e-11	4.34e-09	3.104e-09	ATP6V0D2/SLC48A1/FPR1/CYB561A3/ZFYVE26/STX7/GRN/SLC29A3/CTSA/AZU1/MCOLN1/SLC36A1/MANBA/DRAM2/SLC35F6/RAP1B/ATP8A1/BLOC1S2/TPCN1/CTSD/ECE1/GNAI3/CKAP4/GNB1/ATP6V1C1/MMD/GNB2/AP1B1/ABHD6/ACPP/ABCD4/ATRAID/FLOT1/CLCN7/WDR81/LAMP2/SCARB1/TRIM23/SLC2A6/LAMP3/PSAP/LAMP1/CD74/SPNS1/ATP6V0C/IFITM3/SLC26A11/GPR137B/TMEM192/PLD1/DPP4/M6PR/VPS41/STK11IP/SLC2A8/WDR24/CYBRD1/AP5B1/ARRB1/GNAQ/SEH1L/SLCO4C1/HLA-F/CD63/WDR11/CMTM6/SPPL2A/TCIRG1/ATP11B/AHNAK/PNPLA7/CCZ1B/RNF13/HLA-DPB1/HLA-DPA1/GOPC/ATP6V1A/IGF2R/LAMTOR1/CLN3/VPS33A/LDLR/TMEM9/CD1B/STARD3NL/HLA-DMB/LRP1/NPRL3/TRPM2/TMEM106B/HLA-DOB/PLEKHM1/ATP6V1B2/ABCA5/KPTN/AP5S1/HLA-DRA/AP1M2/OSTM1/HLA-DMA/ATP6V1D/DTX3L/C3AR1/DAGLB/HPSE/VNN1/GDAP2/ARL8A/MGST1/AP2A2/LAMTOR4/TMEM63A/ANXA6/VPS18/TOM1/RAB5C/MFSD8/PI4K2A/AP2S1/CD1D/GPR143/CLN5/GNB4/BRI3/RRAGA/SLC17A5/NAPG/AP2A1/LMBRD1/BLOC1S1/GLIPR1/EEF1A2/LAMTOR5/LAPTM4B/AP1S3/ITFG2/AP3B1/ABCC10/SLC15A3/NFAM1/CPNE1/AP1G1/PSEN1/TLR8/CCZ1/HLA-DQB2/NPRL2/CYB561/AP5M1/VTI1B/GAA/HPS6/EVA1A/TMEM79/NEU1/SLC30A2/CPNE3/AP3M1/AP1M1/STX8/SLC44A2/TMEM30A/HSP90AB1/CLEC16A/TLR3/VPS16/SNAP29/AP2M1/MREG/ANXA2/MTOR/TSPAN1/RAB3D/B4GALT1/DEPDC5/OCA2/ABCD1/LPCAT1/TM6SF1/SIDT2/SLC12A4/CEACAM8/DRAM1/CLCN5/MCOLN3/UBA1/CTNS/DDOST/GNA11/SLC38A9/HLA-DOA/ZNRF2/ARL8B	193
CC	GO:0045335	phagocytic vesicle	86/7377	132/19717	8.745e-11	7.521e-09	5.38e-09	ATP6V0D2/CDC42EP4/TLR1/TLR2/RAB9A/RAC2/APPL2/SLC11A1/MCOLN1/FMNL1/SYT11/VIM/ITGB5/RAB11A/MPEG1/TAP2/TAP1/ATG14/SEC22B/LAMP2/ADAM8/LAMP1/ATP6V0C/PDIA3/RAB31/ANXA3/EVL/STXBP1/RAB23/CDC42EP2/UNC13B/CD36/STXBP2/NCF4/HLA-F/CORO1A/NCF2/TCIRG1/NCF1/HLA-E/HLA-B/VAMP3/CLCN3/ABCA1/RAP1A/RAB20/RAB8A/RAB43/HLA-G/OCRL/RAB32/MYO1C/RAB38/TAPBP/HLA-C/KIF16B/ZYX/SRGAP2/HVCN1/DNM2/ATP6V0E2/RAB5A/CYBA/CYBB/RAB7B/CALR/FLNB/DMBT1/RAB8B/PLD4/RAB22A/STX12/HLA-A/ATP7A/GNLY/STX8/KIF5B/STXBP3/VPS26B/UNC93B1/WAS/APPL1/MPO/STXBP4/TLR6/ATG12	86
CC	GO:0030139	endocytic vesicle	168/7377	303/19717	1.052e-10	8.146e-09	5.827e-09	FCGR1B/ATP6V0D2/CDC42EP4/TLR1/TLR2/RAB9A/RAC2/STX7/APPL2/ARF6/FCGR1A/SLC11A1/WNT5A/MCOLN1/FMNL1/SYT11/VIM/ITGB5/FCHO1/RAB11A/MARCO/MPEG1/TAP2/FCHO2/HEATR5A/WLS/TAP1/STAB1/ATG14/SEC22B/LAMP2/SCARB1/ADAM8/LAMP1/DVL2/CD74/ATP6V0C/RAPGEF6/PDIA3/APOE/RAB31/ANXA3/PLD1/DPP4/TBC1D5/EVL/STXBP1/RAB23/CDC42EP2/UNC13B/RAPGEF2/CD36/LPAR2/STXBP2/NCF4/ROR2/HBB/HLA-F/CORO1A/RAB24/HYAL2/NCF2/TCIRG1/NCF1/ITSN1/HLA-DPB1/HLA-DPA1/HLA-E/HLA-B/VAMP3/CLCN3/IGF2R/ABCA1/CLTB/RAB11FIP4/LDLR/RAP1A/RAB20/LRP1/RAB8A/RAB43/HLA-G/OCRL/HLA-DRA/RAB32/MYO1C/FLOT2/RAB38/TAPBP/CTLA4/CLTCL1/HLA-C/SPARC/KIF16B/ZYX/SRGAP2/SPHK1/HVCN1/SCGB3A2/AP2A2/DNM2/ATP6V0E2/RAB5C/RAB5A/KIAA1107/FFAR4/AP2S1/UBC/INPP5F/CYBA/CYBB/FZD5/CD2AP/RAB7B/LPAR1/CAMK2A/AP2A1/LMBRD1/CALR/FLNB/DMBT1/CAMK2D/CEMIP/RAB8B/RABEP1/EGFR/HSP90B1/PLD4/FZD4/WNT1/RAB22A/MDM2/HLA-DQB2/RAB35/STX12/APOA1/HLA-A/STAB2/ATP7A/GNLY/HP/HYOU1/STX8/KIF5B/HBEGF/EHD3/GPR161/STXBP3/VPS26B/AP2M1/PICK1/WNT6/UNC93B1/FZD2/TIRAP/MTSS1/WNT7A/WAS/PICALM/APPL1/MPO/SMO/STXBP4/GRIA2/TLR6/PTCH1/ATG12/CAMK2B	168
CC	GO:1904813	ficolin-1-rich granule lumen	81/7377	124/19717	2.524e-10	1.776e-08	1.27e-08	SERPINA1/ALOX5/PNP/ASAH1/HK3/QPCT/ATG7/HSPA6/MNDA/CTSD/FCN1/TIMP2/MIF/CTSS/FGL2/GSTP1/VCL/PSMA5/PSMD11/AGL/CST3/ACTR2/COMMD3/PGAM1/PKM/ARSB/ALAD/TNFAIP6/HBB/GMFG/CFD/ALDOC/IMPDH1/GNS/CRISPLD2/CAT/ACLY/CTSZ/PSMB1/ALDOA/MVP/CTSB/PSMD13/CSNK2B/HMGB1/IDH1/PRG2/GPI/ILF2/BIN2/DDX3X/PSMD6/GUSB/PSMC3/PGM2/MMP9/COTL1/YPEL5/CAND1/LRG1/KCMF1/DERA/SRP14/OSTF1/A1BG/CCT8/MAPK1/COMMD9/APEH/PDAP1/XRCC6/PSMA2/HSP90AB1/PYGL/PSMC2/CDA/VCP/AMPD3/KPNB1/PFKL/PSMD3	81
CC	GO:0030667	secretory granule membrane	161/7377	298/19717	3.245e-09	2.093e-07	1.497e-07	ITGAM/FPR2/FPR1/CLEC5A/TLR2/LILRB2/SELL/LILRA3/BST1/GPR84/CD55/SLC11A1/OLR1/AZU1/CLEC4D/MANBA/KCNAB2/RAP1B/ATP8A1/CD58/MCEMP1/MGAM/DIAPH1/CKAP4/LILRB3/FCGR3B/DYNC1LI1/ACPP/CYB5R1/CD93/CD44/LAMP2/SLC2A3/PTPRC/LAMP3/PSAP/DEGS1/ADAM8/LAMP1/CD59/ATP6V0C/CLEC12A/IQGAP2/RAB31/PLD1/FCAR/CD53/PHACTR2/ITPR1/PTAFR/CD36/STXBP2/ITGAL/SLCO4C1/PLA1A/RAP2C/CD63/RAB24/CMTM6/RHOG/TCIRG1/ATP11B/NBEAL2/IZUMO1/IGF2R/SCAMP1/TMED10/RAP2B/LAMTOR1/SIRPB1/RAP1A/SLC27A2/LAIR1/ATP6AP2/TYROBP/TRPM2/CEACAM3/RAC1/CXCR1/PLAUR/CR1/FLOT2/SPARC/ATP6V1D/SRI/SCG3/C3AR1/HVCN1/MOSPD2/VNN1/PAM/ARL8A/P2RX1/MGST1/AP2A2/TMEM63A/RPH3AL/ORMDL3/TOM1/RAB5C/CD47/NRAS/FAM170B/SYTL4/MLEC/CD300A/CYBA/CYBB/HYAL3/PTPRN2/RHOF/BRI3/GLIPR1/ACRBP/DMBT1/FABP5/CXCR2/ICA1/NFAM1/CPNE1/PSEN1/RAB3A/SYT9/GAA/CPNE3/AP1M1/LHFPL2/CLCA1/SYT1/TMX3/SLC44A2/MS4A3/TBC1D10C/TMEM30A/FCGR2A/DBH/SYT2/VAMP1/ABCC4/SERPINB6/SNAP29/SYT4/CD33/SYT5/TEKT3/RHOA/RAB3D/ENPP4/SNCA/B4GALT1/LPCAT1/CEACAM8/SERPINB10/AGPAT2/SYCN/DDOST/RAB27A/RAB26/SIGLEC9/CD109/PTPRJ	161
CC	GO:0005769	early endosome	182/7377	350/19717	1.522e-08	9.06e-07	6.481e-07	FCGR1B/ATP6V0D2/STAM/ANXA1/STX7/APPL2/ARF6/SNX1/FCGR1A/GPNMB/GGA2/STEAP4/WDR91/RASGEF1B/RPS6KC1/PACSIN2/ARRDC4/MAP2K1/SIAH1/WLS/FLOT1/ALS2/ACKR3/WDR81/RABGAP1L/SAMD9L/LAMP3/CD1E/FGD5/HFE/PTP4A1/APOE/RAB31/VPS41/CD22/LDLRAD4/ARRDC3/WDFY2/GRIPAP1/ZFYVE28/MYO5A/HLA-F/NIPA2/CORO1A/CMTM6/NAPEPLD/SNX20/ATP11B/TLR4/ADRB1/HLA-E/DIAPH2/HLA-B/FIG4/EHD4/CLCN3/TRAK2/IGF2R/TMEM230/PMEPA1/CLN3/NUMB/VPS33A/RNF11/LDLR/RAP1A/RAB20/PML/ANKRD27/LRP1/EHD1/CYTIP/NISCH/HLA-G/RAB29/C1orf210/OCRL/RAB32/EPHA8/CLVS2/RAB38/ARC/SNX27/PSEN2/HLA-C/KIF16B/MLC1/SNX6/TMEM127/DTX3L/SPHK1/SH3GL1/PARM1/NIPA1/NRP1/GPR107/VPS18/TOM1/MTMR4/RAB5C/CCDC93/TSG101/SORCS2/RAB5A/ADRB2/VIPAS39/SNX13/DERL1/HGS/MTMR2/MAP2K2/KCNQ1/INPP5F/CD274/WDFY1/CHMP1A/HYAL3/RABGEF1/FZD5/DERL2/F2R/ABCA7/COMMD1/LAPTM4B/RABEP1/EGFR/USP10/KIR2DL4/RCC2/TFRC/RAB22A/PSEN1/ASTN2/MAPK1/VPS29/CLCN4/SNX5/DNER/STX12/APOA1/STAMBP/UHRF1BP1L/VTI1B/HLA-A/HAVCR2/SNX21/HPS6/EPHB1/LMTK2/LLGL1/SNX19/STX8/RET/TRAK1/CD4/MMGT1/TLR3/SNX4/VPS16/VPS26B/RUSC1/ANXA2/PICK1/APP/VAC14/CLIP3/PDLIM4/SLC30A10/APH1A/TM9SF4/CLCN5/MCOLN3/SNX16/PICALM/APPL1/GJA1/ACKR2/VPS8/SIAH2/NTRK2/SNX17/RFTN1	182
CC	GO:0005759	mitochondrial matrix	232/7377	469/19717	4.892e-08	2.678e-06	1.916e-06	SCO2/PDK4/HADHB/HIBADH/CYP27A1/SOD1/CBR4/MTHFD2/ARG2/PARS2/MRPS6/UQCRC2/HADH/FECH/HMGCL/SIRT4/MIPEP/NMNAT3/ALDH7A1/PHYKPL/MTERF1/BCKDK/ACSM5/C12orf65/NARS2/ALDH6A1/GSR/AK3/TRMT5/MRPL35/ALKBH7/LIPT1/PDK2/MRPL45/ETFA/CA5B/NFS1/DGUOK/CLPX/ACOT9/NUDT1/AUH/COQ5/ISCU/CHCHD1/PCK2/BTD/SSBP1/ACADM/DBT/MRPL40/NAGS/NDUFAF7/MRPS30/MRPL34/NDUFS3/ACADS/TFB1M/DECR1/DNAJC19/ETHE1/LACTB2/LARS2/GSTZ1/MCEE/MTERF2/MRPS16/NADK2/PDSS1/GUF1/UQCC2/ALDH2/ME3/PPA2/PARG/ETFDH/SHC1/ADPRHL2/OGDH/COQ3/MRPS14/TRMT61B/CREB1/HAGH/MRPL54/ALDH4A1/CLPP/GRPEL1/BDH1/NUDT9/MRPL44/ACADSB/GLUD1/SLC25A5/LRRK2/PUS1/ADHFE1/MRPL33/ALDH5A1/MLYCD/IDH2/MCCC1/NUDT13/NUBPL/SDHAF1/DHTKD1/OXCT1/IARS2/GRPEL2/SHMT2/NME4/MMAB/TST/PCCB/POLG/SIRT5/ECI1/LDHAL6B/REXO2/MPST/FH/MRPL51/HSD17B10/SUOX/THEM4/OXA1L/ETFB/LYRM7/TEFM/GFM2/PDK1/RNASEL/ACP6/TDRD7/MTRF1L/DIMT1/TYMS/NDUFA10/PDHB/MRPL49/VDAC2/MRPL3/ACADVL/FLAD1/GLS/GOT2/SUCLG2/HADHA/MRPL42/BLOC1S1/FDX1/VDAC1/AGXT2/DLAT/TBRG4/HSPA1L/ATXN3/NDUFS1/DAP3/PDP2/C1QBP/PITRM1/MRPS34/IDH3A/TK2/NDUFB8/ACAA2/AMT/PDHA2/DNAJC15/MARS2/MRPL4/GADD45GIP1/MRPS33/SUPV3L1/ISCA1/CASQ1/MRM1/HARS2/RPUSD3/MRPL20/FPGS/BCKDHB/ALAS1/MRPL46/FAHD1/MRPS18B/MRPL24/MRPL36/PDP1/BCO2/BCAT2/YARS2/ATG4D/PMPCB/ISCA2/DARS2/MRPS15/MRPL48/BCKDHA/TERT/POLRMT/GPX1/PC/NDUFS7/ME2/MRPL41/IDH3G/SNCA/NT5M/HYKK/MRPL2/TRMT10C/GFM1/MPV17L2/SDHAF2/MRPS2/ARL2BP/MRPS9/PDPR/ABHD10/ATXN3L/PIN4/NDUFS2/TIMM44/FOXO3/NDUFA7/WARS2/MRPL30/FASTKD5/MRRF/MRPS17	232
CC	GO:0005766	primary lysosome	91/7377	155/19717	5.536e-08	2.678e-06	1.916e-06	FUCA1/FPR1/HEXB/RNASE2/VAT1/STX7/GRN/CTSA/AZU1/RETN/MANBA/RAP1B/ATP8A1/MNDA/GM2A/CKAP4/NPC2/CREG1/PLAC8/ACPP/CTSC/LAMP2/PSAP/LAMP1/ATP6V0C/HEXA/ACTR2/STK11IP/ARSB/RNASE3/FTL/STXBP2/MAN2B1/PRKCD/SLCO4C1/CD63/GCA/CMTM6/ATP11B/IMPDH1/CAP1/GNS/ACLY/LAMTOR1/GDI2/SDCBP/AGA/GLA/NHLRC3/GUSB/C3AR1/VNN1/ARL8A/MGST1/TOM1/RAB5C/PRDX6/TOLLIP/UNC13D/DSN1/IST1/FRK/CYB5R3/BRI3/GLIPR1/CCT8/FABP5/ARSA/NFAM1/CPNE1/PSEN1/MAPK1/GAA/FUCA2/CPNE3/TMEM30A/CTSG/C6orf120/SNAP29/VCP/ANXA2/PRTN3/RAB3D/B4GALT1/LPCAT1/CEACAM8/PSMD1/MPO/DDOST/PA2G4/PRSS2	91
CC	GO:0042582	azurophil granule	91/7377	155/19717	5.536e-08	2.678e-06	1.916e-06	FUCA1/FPR1/HEXB/RNASE2/VAT1/STX7/GRN/CTSA/AZU1/RETN/MANBA/RAP1B/ATP8A1/MNDA/GM2A/CKAP4/NPC2/CREG1/PLAC8/ACPP/CTSC/LAMP2/PSAP/LAMP1/ATP6V0C/HEXA/ACTR2/STK11IP/ARSB/RNASE3/FTL/STXBP2/MAN2B1/PRKCD/SLCO4C1/CD63/GCA/CMTM6/ATP11B/IMPDH1/CAP1/GNS/ACLY/LAMTOR1/GDI2/SDCBP/AGA/GLA/NHLRC3/GUSB/C3AR1/VNN1/ARL8A/MGST1/TOM1/RAB5C/PRDX6/TOLLIP/UNC13D/DSN1/IST1/FRK/CYB5R3/BRI3/GLIPR1/CCT8/FABP5/ARSA/NFAM1/CPNE1/PSEN1/MAPK1/GAA/FUCA2/CPNE3/TMEM30A/CTSG/C6orf120/SNAP29/VCP/ANXA2/PRTN3/RAB3D/B4GALT1/LPCAT1/CEACAM8/PSMD1/MPO/DDOST/PA2G4/PRSS2	91
CC	GO:0000151	ubiquitin ligase complex	147/7377	282/19717	2.939e-07	1.338e-05	9.573e-06	KLHL21/KLHL13/MAD2L2/WWP1/ATG3/ARMC8/BARD1/KLHL24/CUL1/ENC1/KLHL12/FBXO6/KEAP1/FBXW7/KLHL41/MED10/UBE2N/KLHL15/KCTD17/SKP2/MED11/ZSWIM6/RNF19B/FBXL5/DCUN1D1/DYRK2/UBE4B/PHC2/UBE2S/KCTD10/RANBP9/ZYG11B/PCGF2/UBE2D3/DCAF8/RNF217/IKBKG/FBXO45/DDB1/FBXL20/PCGF1/PCGF3/UBE2D2/UBE2L6/KLHL22/ANKIB1/GID8/FBXO38/RNF11/CBX7/UBE2E1/UBE2A/MED27/FBXL18/FBXL4/RBCK1/FBXO8/KLHL8/CDC23/BCOR/CBLL1/FBXL3/GLMN/RNF7/ANAPC5/KLHL9/ARIH2/KBTBD8/DCUN1D5/TRIM21/YPEL5/NEDD4/CAND1/UBE2D4/ANAPC7/CDKN1B/UBR3/DERL1/DET1/SPSB1/CBX4/PEF1/KLHL40/UBE2C/MED30/RING1/GID4/DERL2/STUB1/DTL/RNF20/CACYBP/FBXO4/DCAF13/COMMD1/CDC26/BRCA1/SPSB2/WWP2/SPOPL/TRAF2/MKLN1/PHC1/KLHL25/FBXL6/DDB2/DCAF15/UBR1/FBXL2/CUL2/DCAF10/ANAPC4/DCAF12/DCUN1D3/FBXL7/CDC27/FBXO27/CDC20/FBXO44/CUL4B/RANBP10/LRRC29/DCAF7/DCUN1D4/FBXO25/FBXL17/ASB1/CUL9/KCTD5/FBXL14/TOPORS/FBXL19/ANAPC11/DEPDC5/RBX1/KLHL42/BRCC3/TRPC4AP/ANAPC13/UBE2B/FBXL12/ZYG11A/FBXL16/OS9/CCNF/ABTB1/ERCC8	147
CC	GO:0045121	membrane raft	161/7377	315/19717	4.222e-07	1.815e-05	1.299e-05	MYADM/MYOF/S100A10/ITGAM/RTN4R/FYN/TLR1/EZR/TLR2/ATP2B4/DLL1/PRKAR2B/TUBA1A/BCL10/LYN/EFHD2/CD55/PPP2CA/PGK1/OLR1/CSK/ATP1A1/STAT6/HCK/CAPN2/CTSD/GNAI3/PTGS2/PLSCR1/TFPI/S1PR1/PACSIN2/BIRC2/CD2/BAALC/FLOT1/LAMP2/SCARB1/JAK2/PTPRC/FAS/TNF/HMOX1/SLC9A1/KRAS/KCNA3/DPP4/LCP2/LRP8/CD226/KCNE3/LAT2/CBLB/CTNNA1/CD36/PTK2B/INSR/HYAL2/AHNAK/CASP3/CASP8/ABCA1/RAP2B/GRIP1/LAMTOR1/FURIN/CLN3/SDCBP/ERLIN2/P2RY12/EFNB1/DMD/SYNJ2/CRK/TRADD/RGS19/LDHB/LCK/SLC25A5/LRRK2/ITLN1/MYO1C/FLOT2/ARC/ADCY1/MLC1/ATP1B3/SELPLG/RGMB/HPSE/EMP2/P2RX1/LAMTOR4/BMPR1A/FXYD1/GNAI2/ATP1B1/MS4A1/BIRC3/RHOQ/PRKACA/PI4K2A/RAB5A/ADD3/RANGRF/CD1A/KCNQ1/ARID3A/ABCB4/UNC5B/RTN4RL1/CORO1C/F2R/VDAC1/LAMTOR5/SPRED1/PPP2R1B/EGFR/MALL/ORAI1/FADD/ADAM17/CAV3/TRAF2/PSEN1/MAPK1/CHRNB2/STX12/PAG1/RTN4RL2/TUBA1B/EPHB1/SKAP1/FAIM2/ATP7A/RET/OPRD1/CD4/PRKCZ/ANXA2/PRTN3/KCNMA1/APP/DAG1/CLIP3/SMPD2/CD8A/LRP4/ATP1A2/GJA1/SMO/ADCYAP1R1/CD24/TLR6/PTCH1/SLC38A9/CNTN1/NTSR1/LAT/BMPR2/RFTN1	161
CC	GO:0030176	integral component of endoplasmic reticulum membrane	86/7377	150/19717	5.339e-07	2.109e-05	1.509e-05	SGMS2/EMC3/SLC37A2/RTN1/TAP2/TAP1/SLC37A4/BCAP31/CD74/EMC2/ELOVL5/PIGK/PDIA3/EXT1/PKD2/EDEM1/SACM1L/DHRS9/SEC62/ARL6IP1/SGPL1/WFS1/SCD/HLA-F/SPPL2A/HLA-DPB1/SARAF/HLA-DPA1/HSPA5/HLA-E/HLA-B/TMEM33/SAMD8/CLN3/SLC37A3/TECR/SLC35B4/SLC27A2/ELOVL7/DGAT2/HLA-G/RCE1/HLA-DRA/RTN2/GPAA1/TEX261/TAPBP/TM7SF2/ANKLE2/HLA-C/DOLK/UBXN8/SGMS1/DERL1/DOLPP1/EMC9/SREBF2/ZMPSTE24/CANX/DERL2/SLC35B1/CALR/INSIG1/RRBP1/XXYLT1/ACER3/BFAR/DPM3/DCSTAMP/HLA-DQB2/HLA-A/TBL2/PIGT/MMGT1/EMC1/RTN4/ERN1/ELOVL6/EMC8/ERGIC2/PREB/TRAM1/G6PC/DPAGT1/ATF6B/ALG3	86
CC	GO:0098857	membrane microdomain	161/7377	316/19717	5.449e-07	2.109e-05	1.509e-05	MYADM/MYOF/S100A10/ITGAM/RTN4R/FYN/TLR1/EZR/TLR2/ATP2B4/DLL1/PRKAR2B/TUBA1A/BCL10/LYN/EFHD2/CD55/PPP2CA/PGK1/OLR1/CSK/ATP1A1/STAT6/HCK/CAPN2/CTSD/GNAI3/PTGS2/PLSCR1/TFPI/S1PR1/PACSIN2/BIRC2/CD2/BAALC/FLOT1/LAMP2/SCARB1/JAK2/PTPRC/FAS/TNF/HMOX1/SLC9A1/KRAS/KCNA3/DPP4/LCP2/LRP8/CD226/KCNE3/LAT2/CBLB/CTNNA1/CD36/PTK2B/INSR/HYAL2/AHNAK/CASP3/CASP8/ABCA1/RAP2B/GRIP1/LAMTOR1/FURIN/CLN3/SDCBP/ERLIN2/P2RY12/EFNB1/DMD/SYNJ2/CRK/TRADD/RGS19/LDHB/LCK/SLC25A5/LRRK2/ITLN1/MYO1C/FLOT2/ARC/ADCY1/MLC1/ATP1B3/SELPLG/RGMB/HPSE/EMP2/P2RX1/LAMTOR4/BMPR1A/FXYD1/GNAI2/ATP1B1/MS4A1/BIRC3/RHOQ/PRKACA/PI4K2A/RAB5A/ADD3/RANGRF/CD1A/KCNQ1/ARID3A/ABCB4/UNC5B/RTN4RL1/CORO1C/F2R/VDAC1/LAMTOR5/SPRED1/PPP2R1B/EGFR/MALL/ORAI1/FADD/ADAM17/CAV3/TRAF2/PSEN1/MAPK1/CHRNB2/STX12/PAG1/RTN4RL2/TUBA1B/EPHB1/SKAP1/FAIM2/ATP7A/RET/OPRD1/CD4/PRKCZ/ANXA2/PRTN3/KCNMA1/APP/DAG1/CLIP3/SMPD2/CD8A/LRP4/ATP1A2/GJA1/SMO/ADCYAP1R1/CD24/TLR6/PTCH1/SLC38A9/CNTN1/NTSR1/LAT/BMPR2/RFTN1	161
CC	GO:0098589	membrane region	166/7377	328/19717	6.322e-07	2.33e-05	1.667e-05	MYADM/MYOF/S100A10/ITGAM/RTN4R/FYN/TLR1/EZR/TLR2/ATP2B4/DLL1/PRKAR2B/TUBA1A/BCL10/LYN/EFHD2/CD55/PPP2CA/PGK1/OLR1/CSK/ATP1A1/STAT6/NUP62/HCK/CAPN2/CTSD/GNAI3/PTGS2/PLSCR1/TFPI/S1PR1/PACSIN2/BIRC2/CD2/BAALC/FLOT1/LAMP2/SCARB1/JAK2/PTPRC/FAS/TNF/HMOX1/SLC9A1/KRAS/KCNA3/DPP4/LCP2/LRP8/CD226/KCNE3/LAT2/CBLB/CTNNA1/CD36/PTK2B/INSR/HYAL2/BICD2/AHNAK/CASP3/CASP8/ABCA1/RAP2B/GRIP1/LAMTOR1/FURIN/CLN3/SDCBP/ERLIN2/P2RY12/EFNB1/DMD/SYNJ2/CRK/TRADD/RGS19/LDHB/LCK/SLC25A5/LRRK2/ITLN1/MYO1C/FLOT2/ARC/ADCY1/MLC1/ATP1B3/SELPLG/RGMB/HPSE/EMP2/P2RX1/LAMTOR4/BMPR1A/FXYD1/GNAI2/ATP1B1/MS4A1/BIRC3/RHOQ/PRKACA/PI4K2A/RAB5A/FAM170B/ADD3/RANGRF/CD1A/KCNQ1/ARID3A/ABCB4/UNC5B/RTN4RL1/CORO1C/F2R/VDAC1/LAMTOR5/SPRED1/PPP2R1B/EGFR/MALL/EIF5A/ORAI1/FADD/ADAM17/CAV3/TRAF2/PSEN1/MAPK1/CHRNB2/STX12/PAG1/RTN4RL2/TUBA1B/EPHB1/SKAP1/FAIM2/ATP7A/RET/OPRD1/CD4/PRKCZ/ANXA2/PRTN3/TEKT3/KCNMA1/APP/DAG1/CLIP3/SMPD2/CD8A/LRP4/ATP1A2/GJA1/SMO/ADCYAP1R1/CD24/TLR6/PTCH1/SLC38A9/CNTN1/NTSR1/LAT/BMPR2/RFTN1	166
CC	GO:0005778	peroxisomal membrane	41/7377	60/19717	1.135e-06	3.821e-05	2.733e-05	ALDH3A2/PEX11A/TMEM135/FNDC5/FAR2/PEX12/ABCD4/PEX11G/MPV17/HMGCR/PEX16/FIS1/ABCD3/MPV17L/ACSL4/CAT/AGPS/ACOX1/SLC27A2/HSD17B4/ACBD5/MAVS/DAO/DECR2/PNPLA8/PXMP4/ARF1/ACSL6/PXMP2/MGST1/PEX13/PEX3/PEX19/MAP2K2/FAR1/RAB8B/PEX14/PEX11B/GNPAT/ABCD1/ATAD1	41
CC	GO:0031903	microbody membrane	41/7377	60/19717	1.135e-06	3.821e-05	2.733e-05	ALDH3A2/PEX11A/TMEM135/FNDC5/FAR2/PEX12/ABCD4/PEX11G/MPV17/HMGCR/PEX16/FIS1/ABCD3/MPV17L/ACSL4/CAT/AGPS/ACOX1/SLC27A2/HSD17B4/ACBD5/MAVS/DAO/DECR2/PNPLA8/PXMP4/ARF1/ACSL6/PXMP2/MGST1/PEX13/PEX3/PEX19/MAP2K2/FAR1/RAB8B/PEX14/PEX11B/GNPAT/ABCD1/ATAD1	41
CC	GO:0044438	microbody part	61/7377	100/19717	1.398e-06	4.328e-05	3.096e-05	ALDH3A2/PEX11A/TMEM135/FNDC5/FAR2/HMGCL/PEX12/ACAA1/ABCD4/PHYH/PEX11G/SCP2/MPV17/HMGCR/PEX16/FIS1/ABCD3/ECH1/MPV17L/ACSL4/CAT/AGPS/ACOX1/ECI2/SLC27A2/HSD17B4/IDH1/ACOX2/ACBD5/MAVS/DAO/DECR2/MLYCD/PNPLA8/PXMP4/ARF1/ACSL6/PXMP2/MGST1/NUDT19/PEX13/TYSND1/PEX3/PEX19/MAP2K2/EHHADH/FAR1/RAB8B/NUDT7/PEX14/PEX11B/ACOX3/GNPAT/CROT/GRHPR/ABCD1/ATAD1/HACL1/HAO1/ACOT8/PIPOX	61
CC	GO:0044439	peroxisomal part	61/7377	100/19717	1.398e-06	4.328e-05	3.096e-05	ALDH3A2/PEX11A/TMEM135/FNDC5/FAR2/HMGCL/PEX12/ACAA1/ABCD4/PHYH/PEX11G/SCP2/MPV17/HMGCR/PEX16/FIS1/ABCD3/ECH1/MPV17L/ACSL4/CAT/AGPS/ACOX1/ECI2/SLC27A2/HSD17B4/IDH1/ACOX2/ACBD5/MAVS/DAO/DECR2/MLYCD/PNPLA8/PXMP4/ARF1/ACSL6/PXMP2/MGST1/NUDT19/PEX13/TYSND1/PEX3/PEX19/MAP2K2/EHHADH/FAR1/RAB8B/NUDT7/PEX14/PEX11B/ACOX3/GNPAT/CROT/GRHPR/ABCD1/ATAD1/HACL1/HAO1/ACOT8/PIPOX	61
CC	GO:0005777	peroxisome	77/7377	134/19717	1.823e-06	5.227e-05	3.739e-05	LACC1/ALDH3A2/PEX11A/SOD1/TMEM135/VIM/FNDC5/FAR2/HMGCL/PEX12/HSDL2/ACAA1/ABCD4/PHYH/PEX11G/AKAP11/SCP2/MPV17/HMGCR/PEX16/ZADH2/TRIM37/TKT/FIS1/ABCD3/MYO5A/ECH1/MPV17L/ACSL4/CAT/AGPS/ACOX1/ECI2/SLC27A2/HSD17B4/IDH1/ACOX2/ACBD5/MAVS/DAO/DECR2/MLYCD/IDH2/PNPLA8/PXMP4/ARF1/ACSL6/PXMP2/IDI1/MGST1/NUDT19/PEX13/TYSND1/PEX3/PEX19/MAP2K2/EHHADH/FAR1/DNM1L/ISOC1/RAB8B/NUDT7/PEX14/MUL1/PEX11B/ACOX3/GNPAT/CROT/CD33/MARC2/GRHPR/ABCD1/ATAD1/HACL1/HAO1/ACOT8/PIPOX	77
CC	GO:0042579	microbody	77/7377	134/19717	1.823e-06	5.227e-05	3.739e-05	LACC1/ALDH3A2/PEX11A/SOD1/TMEM135/VIM/FNDC5/FAR2/HMGCL/PEX12/HSDL2/ACAA1/ABCD4/PHYH/PEX11G/AKAP11/SCP2/MPV17/HMGCR/PEX16/ZADH2/TRIM37/TKT/FIS1/ABCD3/MYO5A/ECH1/MPV17L/ACSL4/CAT/AGPS/ACOX1/ECI2/SLC27A2/HSD17B4/IDH1/ACOX2/ACBD5/MAVS/DAO/DECR2/MLYCD/IDH2/PNPLA8/PXMP4/ARF1/ACSL6/PXMP2/IDI1/MGST1/NUDT19/PEX13/TYSND1/PEX3/PEX19/MAP2K2/EHHADH/FAR1/DNM1L/ISOC1/RAB8B/NUDT7/PEX14/MUL1/PEX11B/ACOX3/GNPAT/CROT/CD33/MARC2/GRHPR/ABCD1/ATAD1/HACL1/HAO1/ACOT8/PIPOX	77
CC	GO:0042581	specific granule	89/7377	160/19717	2.018e-06	5.579e-05	3.991e-05	ITGAM/FPR2/CLEC5A/QPCT/PTPN6/LILRA3/BST1/GPR84/ARMC8/OLR1/RETN/CLEC4D/GHDC/KCNAB2/ATP8A1/MCEMP1/CTSD/CKAP4/TIMP2/ACAA1/CD93/SLC2A3/VCL/DEGS1/ADAM8/CD59/CLEC12A/NFKB1/ANXA3/PLD1/FCAR/CD53/CD36/STXBP2/ITGAL/SLCO4C1/CFP/OSCAR/PTX3/CMTM6/QSOX1/CLCN3/SCAMP1/CTSZ/RAP2B/LAMTOR1/RAP1A/SLC27A2/ERP44/LAIR1/TRPM2/CEACAM3/CHI3L1/PLAUR/CYFIP1/ILF2/ATP6V1D/CNN2/C3AR1/HPSE/HVCN1/MOSPD2/P2RX1/TMEM63A/ORMDL3/TOM1/CD47/LRG1/TOLLIP/MLEC/CYBA/CYBB/FRK/LRRC7/TCN1/NEU1/AP1M1/HP/SLC44A2/MS4A3/TMEM30A/VAMP1/STXBP3/CD33/CEACAM8/KPNB1/AGPAT2/RAB27A/PTPRJ	89
CC	GO:0031227	intrinsic component of endoplasmic reticulum membrane	88/7377	158/19717	2.138e-06	5.708e-05	4.083e-05	SGMS2/EMC3/SLC37A2/RTN1/TAP2/ESYT2/TAP1/SLC37A4/BCAP31/CD74/EMC2/ELOVL5/PIGK/PDIA3/EXT1/PKD2/EDEM1/SACM1L/DHRS9/SEC62/ARL6IP1/SGPL1/WFS1/SCD/HLA-F/SPPL2A/HLA-DPB1/SARAF/HLA-DPA1/HSPA5/HLA-E/HLA-B/TMEM33/SAMD8/CLN3/SLC37A3/TECR/SLC35B4/SLC27A2/ELOVL7/DGAT2/HLA-G/RCE1/HLA-DRA/RTN2/GPAA1/TEX261/TAPBP/TM7SF2/ANKLE2/HLA-C/DOLK/UBXN8/SGMS1/DERL1/DOLPP1/EMC9/SREBF2/ZMPSTE24/CANX/DERL2/SLC35B1/CALR/INSIG1/RRBP1/XXYLT1/ACER3/BFAR/DPM3/DCSTAMP/HLA-DQB2/HLA-A/TBL2/PIGT/MMGT1/EMC1/RTN4/ERN1/ELOVL6/EMC8/ERGIC2/PGAP3/PREB/TRAM1/G6PC/DPAGT1/ATF6B/ALG3	88
CC	GO:0005924	cell-substrate adherens junction	198/7377	408/19717	2.412e-06	6.222e-05	4.451e-05	VASP/EZR/RAC2/ANXA1/TSPAN4/APBB1IP/ARF6/ARHGAP31/STARD8/TES/ITGA5/FLT1/VIM/ITGB7/SORBS3/HCK/LAP3/CAPN2/MRC2/PDLIM1/ITGB5/PROCR/LPXN/CHP1/NEDD9/PLEC/FLNA/FBLIM1/GNB2/PACSIN2/MAP2K1/FHL3/ACTN4/NUP214/FLOT1/ALCAM/CD44/TRIP6/JAK2/PTPRC/VCL/RRAS/CD59/ATP6V0C/SLC9A1/PDIA3/KRAS/ACTR2/RND3/DPP4/LIMA1/PEAK1/EVL/ACTB/TLN1/RDX/PFN1/PARVB/CTNNA1/PAK1/MARCKS/HSPB1/PTK2B/PDLIM7/ACTN1/HNRNPK/RHOG/ITGA4/AHNAK/CD99/CAP1/HSPA5/ACTC1/CAT/SVIL/ARHGAP22/NPM1/IGF2R/ITGA11/CD151/CSPG4/ARHGAP26/NEXN/NUMB/HMGA1/GDI2/ARHGEF2/KLF11/SDCBP/RPL8/MAPRE1/LRP1/RAC1/ARHGAP24/MAPRE2/ARPC1B/PLAUR/CYFIP1/SNTB1/FLOT2/RHOU/CORO1B/PTK2/MYH9/ZYX/ARF1/DIXDC1/CNN2/RPS9/SYNE2/TPM4/RPS19/ARPC5L/LCP1/PGM5/CD99L2/NRP1/ANXA6/LAYN/REXO2/DNM2/TGM2/L1CAM/TLN2/CFL1/MPZL1/PVR/TRIOBP/FHL1/ITGA2/STX16/PCBP2/MAP2K2/CAPN5/ALKBH6/ABCB4/GRB7/CYBA/YWHAQ/ZFYVE21/IRF2/ITGA3/MMP14/SMPX/CORO1C/ACTR3/CALR/FOCAD/FZD1/PXN/LASP1/FLNB/SRP68/PPP1CC/CLASP2/EGFR/ADAM17/CAV3/HSP90B1/FHL2/ADAM9/FLII/MAPK1/GNA13/YWHAE/MSN/ITGA8/SNTB2/RPS16/JAK1/TGFB1I1/CPNE3/HYOU1/PPP1CB/NHS/EHD3/YWHAG/ENAH/EPB41L2/ARPC2/CSRP1/MISP/MAP4K4/RHOA/TRPV4/LIMS1/DAG1/ENG/FZD2/CIB2/PPIB/GJA1/ASAP3/NCKAP1/ARL14EP/MCAM/RPL10A/SLC9A3R2	198
CC	GO:0001726	ruffle	94/7377	172/19717	2.966e-06	7.215e-05	5.161e-05	MYADM/SH2B2/EZR/APPL2/ARF6/ITGA5/DIAPH1/SPATA13/RASGRP2/ARAP3/PLEKHA1/PACSIN2/CIB1/ALS2/KLHL41/FGD6/FGD5/C2CD5/S100A6/S100A11/TESC/LIMA1/TLN1/RDX/PAK1/ARF4/CLIP1/MYO5A/PLEKHO1/PDLIM7/ACTN1/BAIAP2/CAPG/DDX58/FGR/TNFRSF12A/AIF1/S100B/PTK6/ARHGEF2/RAC1/ATP6V1B2/CYFIP1/MYO1C/IFIT5/SH3YL1/MYH9/LCP1/MEFV/LAYN/DNM2/TPM1/INPP5K/MTMR6/TLN2/NME1/THEM4/CFL1/RAB5A/KANK1/PLEK/CD2AP/CORO1C/ABCA7/CLASP2/ADAM17/SPRY2/FSCN1/RAB22A/MKLN1/SNX5/MYO10/FGD3/SKAP1/MTMR9/FGD4/PSD4/WIPF1/EPS8L2/ANXA2/RHOA/TRPV4/ITGB1BP1/SNX9/TIRAP/ARHGEF4/MTSS1/APPL1/ASAP3/NCKAP1/MACF1/WWC1/PSD3/PTPRJ	94
CC	GO:0034399	nuclear periphery	75/7377	131/19717	2.983e-06	7.215e-05	5.161e-05	ALOX5/LMNB1/LMNA/VIM/ATF7/ENC1/CEBPB/JAK2/HAT1/UHRF1/ATF4/EIF6/CENPW/MORC2/ZNF326/CFL2/PRKCD/MBD1/RUVBL2/RUVBL1/ARFGEF1/YEATS4/PSPC1/HNRNPA2B1/RGS12/GMCL1/TEP1/SATB2/KAT8/PML/KIF4A/CSNK2B/PRR14/XPOT/SMARCAD1/SFPQ/ATXN7/NARF/CLIC4/SCAF8/SPARC/AKAP8/SUV39H1/PCNA/ZNF703/PRPF40A/YY1/CFL1/NUP107/RNASEL/CHMP1A/SRPK1/KRT8/HNRNPM/ATXN3/NSMF/NUP93/DNMT3A/SRRM1/NUP205/TELO2/SMC3/ANAPC4/CAD/NUFIP1/ATXN1/TGFB1I1/DCAF7/MEN1/STAG1/POLA1/PRKCZ/DAG1/PAXIP1/ERCC8	75
CC	GO:0042470	melanosome	63/7377	106/19717	3.321e-06	7.314e-05	5.232e-05	RAB9A/GPNMB/ATP1A1/ERP29/TPP1/CTSD/HPS4/SYTL1/AHCY/FLOT1/SEC22B/LAMP1/PDIA3/RAN/SND1/SYPL1/PRDX1/MYO5A/CD63/CAPG/HSPA5/SLC1A4/TMED10/TMEM33/DTNBP1/SDCBP/CTSB/ANKRD27/RAC1/RAB29/ATP6V1B2/RAB32/RAB38/ATP1B3/PDIA6/ANXA6/RAB5C/RAB5A/GANAB/GPR143/MMP14/CCT4/ATP6V1G2/CANX/DCT/HSP90B1/TFRC/ANXA2P2/GNA13/RAB35/YWHAE/SYTL2/HSP90AB1/CNP/MREG/ANXA2/CALU/OCA2/PPIB/CTNS/RAB27A/TRPV2/GCHFR	63
CC	GO:0048770	pigment granule	63/7377	106/19717	3.321e-06	7.314e-05	5.232e-05	RAB9A/GPNMB/ATP1A1/ERP29/TPP1/CTSD/HPS4/SYTL1/AHCY/FLOT1/SEC22B/LAMP1/PDIA3/RAN/SND1/SYPL1/PRDX1/MYO5A/CD63/CAPG/HSPA5/SLC1A4/TMED10/TMEM33/DTNBP1/SDCBP/CTSB/ANKRD27/RAC1/RAB29/ATP6V1B2/RAB32/RAB38/ATP1B3/PDIA6/ANXA6/RAB5C/RAB5A/GANAB/GPR143/MMP14/CCT4/ATP6V1G2/CANX/DCT/HSP90B1/TFRC/ANXA2P2/GNA13/RAB35/YWHAE/SYTL2/HSP90AB1/CNP/MREG/ANXA2/CALU/OCA2/PPIB/CTNS/RAB27A/TRPV2/GCHFR	63
CC	GO:0030055	cell-substrate junction	199/7377	412/19717	3.378e-06	7.314e-05	5.232e-05	VASP/EZR/RAC2/ANXA1/TSPAN4/APBB1IP/ARF6/ARHGAP31/STARD8/TES/ITGA5/FLT1/VIM/ITGB7/SORBS3/HCK/LAP3/CAPN2/MRC2/PDLIM1/ITGB5/PROCR/LPXN/CHP1/NEDD9/PLEC/FLNA/FBLIM1/GNB2/PACSIN2/MAP2K1/FHL3/ACTN4/NUP214/FLOT1/ALCAM/CD44/TRIP6/JAK2/PTPRC/VCL/RRAS/CD59/ATP6V0C/SLC9A1/PDIA3/KRAS/ACTR2/RND3/DPP4/LIMA1/PEAK1/EVL/ACTB/TLN1/RDX/PFN1/PARVB/CTNNA1/PAK1/MARCKS/HSPB1/PTK2B/PDLIM7/ACTN1/HNRNPK/RHOG/ITGA4/AHNAK/CD99/CAP1/HSPA5/ACTC1/CAT/SVIL/ARHGAP22/NPM1/IGF2R/ITGA11/CD151/CSPG4/ARHGAP26/NEXN/NUMB/HMGA1/GDI2/ARHGEF2/KLF11/SDCBP/RPL8/MAPRE1/LRP1/DMD/RAC1/ARHGAP24/MAPRE2/ARPC1B/PLAUR/CYFIP1/SNTB1/FLOT2/RHOU/CORO1B/PTK2/MYH9/ZYX/ARF1/DIXDC1/CNN2/RPS9/SYNE2/TPM4/RPS19/ARPC5L/LCP1/PGM5/CD99L2/NRP1/ANXA6/LAYN/REXO2/DNM2/TGM2/L1CAM/TLN2/CFL1/MPZL1/PVR/TRIOBP/FHL1/ITGA2/STX16/PCBP2/MAP2K2/CAPN5/ALKBH6/ABCB4/GRB7/CYBA/YWHAQ/ZFYVE21/IRF2/ITGA3/MMP14/SMPX/CORO1C/ACTR3/CALR/FOCAD/FZD1/PXN/LASP1/FLNB/SRP68/PPP1CC/CLASP2/EGFR/ADAM17/CAV3/HSP90B1/FHL2/ADAM9/FLII/MAPK1/GNA13/YWHAE/MSN/ITGA8/SNTB2/RPS16/JAK1/TGFB1I1/CPNE3/HYOU1/PPP1CB/NHS/EHD3/YWHAG/ENAH/EPB41L2/ARPC2/CSRP1/MISP/MAP4K4/RHOA/TRPV4/LIMS1/DAG1/ENG/FZD2/CIB2/PPIB/GJA1/ASAP3/NCKAP1/ARL14EP/MCAM/RPL10A/SLC9A3R2	199
CC	GO:0005925	focal adhesion	196/7377	405/19717	3.402e-06	7.314e-05	5.232e-05	VASP/EZR/RAC2/ANXA1/TSPAN4/APBB1IP/ARF6/ARHGAP31/STARD8/TES/ITGA5/FLT1/VIM/ITGB7/SORBS3/HCK/LAP3/CAPN2/MRC2/PDLIM1/ITGB5/PROCR/LPXN/CHP1/NEDD9/PLEC/FLNA/FBLIM1/GNB2/PACSIN2/MAP2K1/FHL3/ACTN4/NUP214/FLOT1/ALCAM/CD44/TRIP6/JAK2/PTPRC/VCL/RRAS/CD59/ATP6V0C/SLC9A1/PDIA3/KRAS/ACTR2/RND3/DPP4/LIMA1/PEAK1/EVL/ACTB/TLN1/RDX/PFN1/PARVB/CTNNA1/PAK1/MARCKS/HSPB1/PTK2B/PDLIM7/ACTN1/HNRNPK/RHOG/ITGA4/AHNAK/CD99/CAP1/HSPA5/ACTC1/CAT/SVIL/ARHGAP22/NPM1/IGF2R/ITGA11/CD151/CSPG4/ARHGAP26/NEXN/NUMB/HMGA1/GDI2/ARHGEF2/KLF11/SDCBP/RPL8/MAPRE1/LRP1/RAC1/ARHGAP24/MAPRE2/ARPC1B/PLAUR/CYFIP1/SNTB1/FLOT2/RHOU/CORO1B/PTK2/MYH9/ZYX/ARF1/DIXDC1/CNN2/RPS9/SYNE2/TPM4/RPS19/ARPC5L/LCP1/PGM5/CD99L2/NRP1/ANXA6/LAYN/REXO2/DNM2/TGM2/L1CAM/TLN2/CFL1/MPZL1/PVR/TRIOBP/FHL1/ITGA2/STX16/PCBP2/MAP2K2/CAPN5/ALKBH6/ABCB4/GRB7/CYBA/YWHAQ/ZFYVE21/IRF2/ITGA3/MMP14/CORO1C/ACTR3/CALR/FOCAD/FZD1/PXN/LASP1/FLNB/SRP68/PPP1CC/CLASP2/EGFR/ADAM17/CAV3/HSP90B1/FHL2/ADAM9/FLII/MAPK1/GNA13/YWHAE/MSN/ITGA8/SNTB2/RPS16/JAK1/TGFB1I1/CPNE3/HYOU1/PPP1CB/NHS/EHD3/YWHAG/ENAH/EPB41L2/ARPC2/CSRP1/MISP/MAP4K4/RHOA/TRPV4/LIMS1/DAG1/ENG/FZD2/PPIB/GJA1/ASAP3/NCKAP1/ARL14EP/MCAM/RPL10A/SLC9A3R2	196
CC	GO:0031461	cullin-RING ubiquitin ligase complex	87/7377	158/19717	4.558e-06	9.535e-05	6.821e-05	KLHL21/KLHL13/MAD2L2/KLHL24/CUL1/ENC1/KLHL12/FBXO6/KEAP1/FBXW7/KLHL41/KLHL15/KCTD17/SKP2/ZSWIM6/FBXL5/UBE2S/KCTD10/ZYG11B/DCAF8/FBXO45/DDB1/FBXL20/KLHL22/FBXO38/FBXL18/FBXL4/KLHL8/CDC23/FBXL3/GLMN/RNF7/ANAPC5/KLHL9/ARIH2/KBTBD8/TRIM21/CAND1/ANAPC7/CDKN1B/DET1/SPSB1/PEF1/KLHL40/UBE2C/DTL/CACYBP/FBXO4/DCAF13/COMMD1/CDC26/SPSB2/SPOPL/KLHL25/FBXL6/DDB2/DCAF15/FBXL2/CUL2/DCAF10/ANAPC4/DCAF12/FBXL7/CDC27/FBXO27/CDC20/FBXO44/CUL4B/LRRC29/DCAF7/FBXO25/FBXL17/CUL9/KCTD5/FBXL14/FBXL19/ANAPC11/DEPDC5/RBX1/KLHL42/TRPC4AP/ANAPC13/FBXL12/ZYG11A/FBXL16/CCNF/ERCC8	87
CC	GO:0030666	endocytic vesicle membrane	91/7377	167/19717	4.981e-06	0.0001014	7.257e-05	FCGR1B/ATP6V0D2/TLR1/TLR2/RAB9A/RAC2/APPL2/FCGR1A/SLC11A1/WNT5A/MCOLN1/FCHO1/MARCO/TAP2/FCHO2/WLS/TAP1/STAB1/SEC22B/LAMP2/SCARB1/LAMP1/CD74/ATP6V0C/APOE/RAB31/ANXA3/TBC1D5/RAB23/CD36/ROR2/HLA-F/CORO1A/TCIRG1/HLA-DPB1/HLA-DPA1/HLA-E/HLA-B/VAMP3/LDLR/RAB20/LRP1/RAB8A/RAB43/HLA-G/OCRL/HLA-DRA/RAB32/RAB38/TAPBP/HLA-C/HVCN1/AP2A2/DNM2/ATP6V0E2/RAB5A/KIAA1107/AP2S1/UBC/CYBA/CYBB/FZD5/RAB7B/CAMK2A/AP2A1/CALR/DMBT1/CAMK2D/RAB8B/FZD4/WNT1/RAB22A/MDM2/HLA-DQB2/HLA-A/STAB2/ATP7A/HBEGF/GPR161/AP2M1/PICK1/WNT6/FZD2/WNT7A/PICALM/SMO/GRIA2/TLR6/PTCH1/ATG12/CAMK2B	91
CC	GO:0030135	coated vesicle	145/7377	289/19717	5.764e-06	0.0001144	8.183e-05	NRGN/FCGR1B/SERPINA1/F5/FCGR1A/WNT5A/MCFD2/ECE1/GGA2/FCHO1/LMAN2L/KLHL12/AP1B1/FCHO2/CTSC/DENND1A/SEC22B/BCAP31/CD59/DVL2/CD74/APOE/TBC1D5/M6PR/VPS41/IL7R/DENND1B/SLC2A8/SH3BP4/AFTPH/SAR1B/ROR2/HLA-F/CNIH3/SNX18/COPE/HLA-DPB1/HLA-DPA1/GOPC/HLA-E/HLA-B/VAMP3/IGF2R/SCAMP1/CTSZ/ARFGAP3/TMED10/CLTB/FURIN/NUMB/VPS33A/CD3D/LDLR/LRP1/WIPI1/RAB8A/RGS19/HLA-G/CCDC88A/IDUA/OCRL/GOSR2/HLA-DRA/AP1M2/AP1G2/CLVS2/TEX261/CTLA4/IER3IP1/CLTCL1/STX5/HLA-C/SAR1A/ARF1/KDELR3/AP2A2/GPR107/VPS18/DNM2/SCAP/COPG2/COL7A1/UNC13D/RAB5A/COPA/KIAA1107/ADRB2/AP2S1/CD3G/KDELR2/ABCB4/INPP5F/LMAN1/VTI1A/NECAP2/PEF1/SREBF2/FZD5/VWF/CHRM2/AP2A1/LMBRD1/TMED5/CEMIP/SEC23IP/RAB8B/EGFR/ARCN1/MALL/AP3B1/FZD4/TFRC/DVL1/AP1G1/VMA21/ASTN2/TMED4/RAB3A/HLA-DQB2/RAB35/VTI1B/SYT9/YIPF6/HLA-A/ATP7A/AP1M1/COPZ2/SYT1/HBEGF/CD4/YIF1B/SYT2/YIF1A/VPS16/AP2M1/APP/SNX9/FZD2/ERGIC2/PICALM/SEC24A/RAB27A/AVPR2/SEC31B/SEC16B	145
CC	GO:0035579	specific granule membrane	55/7377	91/19717	6.762e-06	0.0001309	9.361e-05	ITGAM/FPR2/CLEC5A/LILRA3/BST1/GPR84/OLR1/CLEC4D/KCNAB2/ATP8A1/MCEMP1/CKAP4/CD93/SLC2A3/DEGS1/ADAM8/CD59/CLEC12A/PLD1/FCAR/CD53/CD36/ITGAL/SLCO4C1/CMTM6/SCAMP1/RAP2B/LAMTOR1/RAP1A/SLC27A2/LAIR1/TRPM2/CEACAM3/PLAUR/ATP6V1D/C3AR1/HVCN1/MOSPD2/P2RX1/TMEM63A/ORMDL3/TOM1/CD47/MLEC/CYBA/CYBB/AP1M1/SLC44A2/MS4A3/TMEM30A/VAMP1/CD33/CEACAM8/AGPAT2/PTPRJ	55
CC	GO:0005770	late endosome	130/7377	256/19717	7.985e-06	0.0001507	0.0001078	CRHBP/RAB9A/CYB561A3/STX7/GRN/SLC29A3/SLC11A1/SLC9A9/MCOLN1/WDR91/RAB11A/RASGEF1B/MMD/ABHD6/CTSS/MAP2K1/OSBPL9/LGMN/SQSTM1/WDR81/LAMP2/LAMP3/VAMP5/PSAP/IFNAR1/CD1E/LAMP1/CD74/SLC31A2/VPS37B/IFITM3/TMEM192/PLD1/M6PR/VPS41/CHMP4B/CHID1/OSBPL1A/MAP1LC3A/RAPGEF2/MYO5A/STEAP3/MICALL1/CD63/SPPL2A/TCIRG1/CCZ1B/RNF13/FIG4/CLCN3/IGF2R/TMEM230/LAMTOR1/CLN3/VPS33A/VPS37C/LDLR/TMEM9/RAP1A/STARD3NL/HLA-DMB/ANKRD27/ATP7B/TMEM106B/ABCA5/GOSR2/AP5S1/HLA-DRA/LRRK2/GNPNAT1/CLTCL1/HLA-DMA/CST7/ARF1/ATG9A/PARM1/ARL8A/LAMTOR4/ANXA6/VPS18/CHMP2A/TSG101/UNC13D/VIPAS39/DERL1/HGS/MAP2K2/KCNQ1/VTI1A/CHMP1A/VPS4B/NMNAT2/RAB7B/MCOLN2/DERL2/F2R/LAMTOR5/LAPTM4B/EGFR/LTV1/RAB22A/ASTN2/CCZ1/MAPK1/VPS29/CLCN4/AP5M1/VTI1B/ATP7A/SLC30A2/STX8/CLEC16A/IL12B/VPS16/DYNC1LI2/SLA2/VPS26B/ANKRD13D/MREG/ANXA2/VAC14/NBR1/CHMP1B/MCOLN3/SNX16/CTNS/GJA1/RAB27A/SLC38A9/ARL8B	130
CC	GO:0005802	trans-Golgi network	121/7377	236/19717	9.012e-06	0.0001661	0.0001188	RAB9A/GRN/DENND5A/ATP8A1/ARAP1/LAP3/GGA2/RAB11A/AP1B1/WLS/DPY30/CD74/SYS1/RAB31/SCAMP2/M6PR/CHID1/AFTPH/TRAPPC6A/COG8/FAM91A1/CHST2/WDR11/CBY1/ARFGEF1/ATP11B/HLA-DPB1/HLA-DPA1/VAMP3/IGF2R/SCAMP1/ARFGAP3/TMEM230/C16orf70/CLTB/FURIN/CLN3/CNST/C17orf75/ATP2C1/WIPI1/RAB8A/ATP7B/RAB43/CHST5/RAC1/RAB29/PREPL/OCRL/HLA-DRA/AP1M2/LRRK2/RAB32/CLVS2/ATXN2/RAB38/CLTCL1/SLC9A7/BACE2/BICD1/GCNT1/ARF1/ATG9A/PLEKHA8/PAM/PCSK7/SCAMP4/TRAPPC6B/TRAPPC9/GOLPH3L/DNM2/VPS51/INPP5K/COG4/AP4S1/PI4K2A/STX16/GOLGA1/PCSK5/KIF13A/TJAP1/VPS52/ARL1/VTI1A/COG6/ARFRP1/NMNAT2/RAB7B/AP4B1/CLASP2/AP1S3/PLD4/AP1G1/HLA-DQB2/LGR5/CALN1/COG2/YIPF6/COG1/RGS20/RHOBTB3/TMEM79/LLGL1/ATP7A/AP1M1/STX8/COG7/OPTN/LGR6/TGFBI/SCAMP5/RABEPK/PICK1/APP/CLIP3/SNX9/AZIN2/RGP1/GSAP/CCDC91/CHST7	121
CC	GO:0031301	integral component of organelle membrane	111/7377	214/19717	1.061e-05	0.0001911	0.0001367	SCO2/SGMS2/SUN2/PEX11A/PINK1/CHCHD6/ZDHHC20/SYT11/TIMM23B/SLC25A19/FAR2/MAN1C1/PEX12/LFNG/LAMP2/COX11/GDAP1/PEX11G/VAMP5/P2RX7/LAMP1/QSOX2/SYS1/TMEM43/PEX16/ITM2B/SYPL1/UNC50/FIS1/TMEM70/WFS1/APOO/MCU/CSGALNACT1/ABCB6/RYR1/QSOX1/VAMP3/SAMD8/FURIN/TIMM17A/RHOT2/ETFDH/SLC35B4/SLC27A2/MPC2/BET1/CHCHD10/ABCB10/VOPP1/AFG3L2/SLC39A13/TVP23C/TEX261/IER3IP1/ARMCX3/TVP23B/PCSK7/P2RX1/TMEM201/TBC1D20/COX16/SGMS1/OXA1L/B4GALNT1/PEX13/SFXN1/CSGALNACT2/STX16/PEX3/PCSK5/TOMM40/CPT1A/MICU1/PTPRN2/FAR1/PET100/TVP23A/SLC35B1/SLC35A3/TOMM20/COA3/MUL1/PEX11B/AGK/SLC35A5/ACER3/STX12/SYT9/L2HGDH/CHST12/SYT1/OPRD1/LEMD3/YIF1B/YIF1A/VAMP1/SYT4/SYT5/P2RX2/ABCD1/RER1/BAK1/ERGIC2/SLC35A2/APOOL/MGARP/SLC38A9/P2RX5/FUNDC1/TMEM177	111
CC	GO:0031300	intrinsic component of organelle membrane	121/7377	237/19717	1.168e-05	0.0002054	0.0001469	SCO2/SGMS2/SUN2/PEX11A/PINK1/CHCHD6/ZDHHC20/SYT11/TIMM23B/SLC25A19/ECE1/FAR2/MAN1C1/PEX12/LFNG/LAMP2/COX11/GDAP1/PEX11G/VAMP5/P2RX7/LAMP1/QSOX2/SYS1/TMEM43/PEX16/ITM2B/ZDHHC9/SYPL1/UNC50/FIS1/TMEM70/WFS1/APOO/CHST2/MCU/CSGALNACT1/ABCB6/RYR1/QSOX1/VAMP3/SAMD8/FURIN/TIMM17A/RHOT2/ETFDH/SLC35B4/SLC27A2/MPC2/BET1/CHCHD10/ABCB10/VOPP1/AFG3L2/SLC39A13/CHST5/TVP23C/TEX261/IER3IP1/ARMCX3/TVP23B/PCSK7/P2RX1/TMEM201/TBC1D20/COX16/SGMS1/OXA1L/B4GALNT1/RAB5A/PEX13/SFXN1/CSGALNACT2/STX16/PEX3/PCSK5/TOMM40/CPT1A/MICU1/PTPRN2/FAR1/PET100/TVP23A/SLC35B1/SLC35A3/TOMM20/COA3/MUL1/PEX11B/AGK/SLC35A5/ACER3/RAB3A/RAB35/STX12/SYT9/L2HGDH/CHST12/SYT1/OPRD1/RAB3B/LEMD3/YIF1B/YIF1A/VAMP1/SYT4/SYT5/MREG/P2RX2/ABCD1/RER1/BAK1/ERGIC2/SLC35A2/APOOL/MGARP/RAB26/SLC38A9/P2RX5/FUNDC1/TMEM177	121
CC	GO:0031968	organelle outer membrane	105/7377	201/19717	1.218e-05	0.0002094	0.0001498	BMF/VAT1/PINK1/HADHB/ARMCX1/GPAM/PPP1R15A/PMAIP1/BCL2A1/CISD2/ACSL5/GK/GDAP1/RETSAT/AIFM2/FAM210B/NUCB2/MIEF1/FIS1/CYB5B/BRI3BP/CYB5A/MCL1/ABCB6/TMEM109/MAOA/ACSL4/IFI27/RSAD2/CASP8/CCDC155/EMD/RHOT2/ACACB/STARD7/RAF1/MAVS/LRRK2/CLMN/RAB32/DAO/AGPAT4/ARMCX3/DDX3X/MTX1/BPHL/ACSL6/SYNE2/LETMD1/BCL2L11/MGST1/ARMCX2/BCL2/BAX/SLC25A46/PPP2R2B/TOMM22/TOMM40L/NME1/QTRT1/UBC/TOMM40/CPT1A/VDAC2/USP30/CISD1/CYB5R3/CPTP/DNM1L/TOMM20/VDAC1/PPP1CC/ULK1/MUL1/AGK/AGPAT5/MAOB/PSEN1/SH3GLB1/CYP27B1/GUCY2D/BAD/MOAP1/TOMM5/NLRX1/RNF185/CNP/VAMP1/VDAC3/MARC2/MTOR/NAV3/SNCA/SIGMAR1/BAK1/MSTO1/BCL2L2/SLC8A3/GJA1/SNN/TOMM34/MGARP/FOXO3/FUNDC1/PI4KB	105
CC	GO:0005635	nuclear envelope	218/7377	464/19717	1.28e-05	0.0002154	0.0001541	MYOF/ALOX5/RAC2/LMNB1/TRA2B/GCH1/SUN2/CLIC1/ALOX5AP/LMNA/NXF1/GHDC/C9orf72/STAT6/NUP62/NUP160/GAPDH/SLC22A18/KLHDC2/PRPF38A/NUP214/ATRAID/ENY2/AGFG1/SHISA5/MGST2/CBX5/CERS2/RETSAT/P2RX7/QSOX2/S100A6/ZNF383/TMEM43/RAN/GRK5/CCND2/TMC8/CHMP4B/NRM/NUCB2/CDK4/MX2/ITPR1/UNC50/NUP85/NXT1/GTPBP4/CETN3/NUDT1/GNAQ/PAK1/SCRN1/SEH1L/PCM1/CLIP1/INTS5/INSR/ZBTB1/NAPEPLD/BICD2/KPNA4/CERS5/DUSP2/ATP11B/PHF11/PNPLA7/ITSN1/RNF13/NUP43/TMEM109/IFI27/YEATS4/ABL1/IGF2R/AGPAT3/PAFAH1B1/CCDC155/EMD/DNAJC2/TMEM33/HTATIP2/PARP16/MVP/SNUPN/DDX19B/TXNL4A/SDCBP/POM121/C2orf42/TMEM18/XPOT/SIRT1/GPX4/DNASE1/CERS4/TOR1B/TMEM97/THAP7/DPY19L4/CLMN/MYO1C/DNAJC1/RCC1/TFPT/CREB3L4/TM7SF2/ZNF224/SUMO1/PUM2/PSEN2/ROGDI/BANF1/SYNE2/AEN/TOR1A/IL15RA/SCGB1A1/SCAI/ZNF354C/P2RX1/OIT3/BCL2/TMEM201/TBC1D20/EI24/BAX/NUP88/CHMP2A/ANKRD17/CBX3/MTMR6/MX1/MAD2L1BP/CSE1L/NUP107/IST1/NDEL1/PHF20/MLX/CYBB/SLC29A2/C12orf43/CPTP/ZMPSTE24/NPIPA1/DTL/CALR/NXT2/FANCL/NUP62CL/CACYBP/NSMF/INTS2/PLCB1/EGFR/EIF5A/NUP93/CETN2/IPO9/AGPAT5/PLCD4/EPC1/ZC3HC1/CPNE1/PSEN1/NUP205/MGST3/RNF43/IPO7/APEH/DPY19L2/GTF3C3/GUCY2D/KPNA1/SPAG4/ATP1B4/TMPO/NUP50/NOC4L/PARP11/UBE2I/INA/MCM3AP/PCID2/TMEM38B/LEMD3/LMNTD1/POLA1/TOR4A/NPAP1/MTDH/PRKCZ/HPN/NAV3/TYRO3/APP/RTN4/ERN1/SNCA/P2RX2/SIGMAR1/ALG14/KPNB1/XPO4/CMTM3/DCTN5/ACKR2/HOXA7/BIN1/TOR3A/POM121C/DPY19L2P2/AAAS/POMZP3/P2RX5/GCHFR/RRP12	218
CC	GO:0030670	phagocytic vesicle membrane	47/7377	76/19717	1.314e-05	0.0002164	0.0001548	ATP6V0D2/TLR1/TLR2/RAB9A/RAC2/APPL2/SLC11A1/MCOLN1/TAP2/TAP1/SEC22B/LAMP2/LAMP1/ATP6V0C/RAB31/ANXA3/RAB23/HLA-F/CORO1A/TCIRG1/HLA-E/HLA-B/VAMP3/RAB20/RAB8A/RAB43/HLA-G/OCRL/RAB32/RAB38/TAPBP/HLA-C/HVCN1/DNM2/ATP6V0E2/RAB5A/CYBA/CYBB/RAB7B/CALR/DMBT1/RAB8B/RAB22A/HLA-A/ATP7A/TLR6/ATG12	47
CC	GO:0031252	cell leading edge	192/7377	403/19717	1.455e-05	0.0002345	0.0001678	MYADM/SH2B2/MYO1G/VASP/EZR/RAC2/DPYSL3/APBB1IP/APPL2/ARF6/SNX1/TSC1/ARHGAP31/ITGA5/FAM89B/VIM/DIAPH1/SPATA13/RASGRP2/SH3RF1/NEDD9/ARAP3/PLEKHA1/PACSIN2/KITLG/CIB1/WLS/FLOT1/ALS2/CD44/PSTPIP1/KLHL41/LDB1/FGD6/FGD5/KCNC4/C2CD5/SLC9A1/S100A6/S100A11/TESC/PKD2/IQGAP2/ACTR2/PTPRO/PTPN13/DPP4/ATF4/LIMA1/EVL/DOCK8/TWF2/TLN1/PLEK2/RDX/SRA1/PARVB/CTNNA1/PAK1/ARF4/CLIP1/PTK2B/MYO5A/PLEKHO1/MCC/SWAP70/PDLIM7/INSR/ACTN1/CORO1A/BAIAP2/CAPG/DDX58/ITSN1/FGR/ACTC1/CDK5/TNFRSF12A/ABL1/ARHGEF6/PAFAH1B1/TUBB3/CSPG4/AIF1/S100B/PTK6/ARHGEF2/ACTA2/SLK/SH3BP1/RAC1/ARPIN/SPTBN1/CCDC88A/ATP6V1B2/KPTN/CYFIP1/MYO1C/IFIT5/SH3YL1/FLOT2/CORO1B/PTK2/MYH9/ARF1/SYNE2/SRGAP2/CTNNA3/LCP1/ABLIM3/PLXND1/MEFV/LAYN/DNM2/TPM1/INPP5K/MTMR6/BCAS3/SHISA9/TLN2/NME1/THEM4/CFL1/RAB5A/KANK1/NDEL1/PLEK/JMY/FER/CD2AP/CORO1C/KCNA2/ACTR3/ABCA7/PXN/MYLK/CLASP2/UNC5C/PKN2/ADAM17/SPRY2/FSCN1/ABI3/RAB22A/MKLN1/SNX5/MYO10/ITGA8/RUFY3/FGD3/SKAP1/ATP7A/MTMR9/OPRD1/GABARAPL1/NHS/PHACTR4/FGD4/PSD4/ENAH/WIPF1/NRBP1/ARPC2/PRKCZ/EPS8L2/ANXA2/RHOA/TRPV4/APP/DAG1/GABRA4/PDLIM4/ITGB1BP1/SNX9/SSH1/TIRAP/AMOTL1/ARHGEF4/MTSS1/SHISA8/APPL1/ACTA1/INPPL1/ASAP3/NCKAP1/MACF1/WWC1/PSD3/AMPH/PTPRM/PTPRJ/ABLIM1	192
CC	GO:0070820	tertiary granule	88/7377	164/19717	1.58e-05	0.0002496	0.0001785	ITGAM/FPR2/FPR1/CLEC5A/ASAH1/QPCT/PTPN6/LILRB2/LILRA3/STX7/GPR84/CD55/SLC11A1/ARMC8/OLR1/CLEC4D/KCNAB2/CD58/MCEMP1/MGAM/DIAPH1/CTSD/TIMP2/DYNC1LI1/CTSS/CD93/PPBP/LAMP2/SLC2A3/ADAM8/LAMP1/CD59/ATP6V0C/CLEC12A/CST3/PLD1/FCAR/CD53/TNFAIP6/PTAFR/STXBP2/CFP/HBB/RAP2C/OSCAR/PTX3/ALDOC/TCIRG1/NBEAL2/QSOX1/ALDOA/RAP2B/LAMTOR1/LAIR1/ATP6AP2/IDH1/TRPM2/RAC1/CR1/PRSS3/CYFIP1/ILF2/CNN2/ARL8A/AP2A2/TMEM63A/MMP9/YPEL5/CD47/LRG1/NRAS/CD300A/CYBA/CYBB/PTPRN2/TCN1/GAA/HP/TBC1D10C/VAMP1/SERPINB6/STXBP3/CDA/CD33/RHOA/ENPP4/CEACAM8/SERPINB10	88
CC	GO:0005758	mitochondrial intermembrane space	48/7377	79/19717	2.1e-05	0.000321	0.0002297	LYN/PINK1/TXNIP/AIFM1/SOD1/CAPN2/PANK2/NDUFA8/PRELID1/AK2/COX19/CMC4/HTRA2/FGR/CAT/CPOX/TIMM8B/UQCC2/GATM/CHCHD10/FBXL4/CHCHD7/NLN/TIMM10B/SHMT2/NME4/SIRT5/REXO2/SUOX/COA7/THEM4/COA6/MICU1/BLOC1S1/NDUFS1/COA4/AGK/PRELID2/CHCHD2/DIABLO/THOP1/TRIAP1/SNCA/PNPT1/ARL2BP/MICU2/CIAPIN1/TIMM9	48
CC	GO:0019867	outer membrane	105/7377	203/19717	2.115e-05	0.000321	0.0002297	BMF/VAT1/PINK1/HADHB/ARMCX1/GPAM/PPP1R15A/PMAIP1/BCL2A1/CISD2/ACSL5/GK/GDAP1/RETSAT/AIFM2/FAM210B/NUCB2/MIEF1/FIS1/CYB5B/BRI3BP/CYB5A/MCL1/ABCB6/TMEM109/MAOA/ACSL4/IFI27/RSAD2/CASP8/CCDC155/EMD/RHOT2/ACACB/STARD7/RAF1/MAVS/LRRK2/CLMN/RAB32/DAO/AGPAT4/ARMCX3/DDX3X/MTX1/BPHL/ACSL6/SYNE2/LETMD1/BCL2L11/MGST1/ARMCX2/BCL2/BAX/SLC25A46/PPP2R2B/TOMM22/TOMM40L/NME1/QTRT1/UBC/TOMM40/CPT1A/VDAC2/USP30/CISD1/CYB5R3/CPTP/DNM1L/TOMM20/VDAC1/PPP1CC/ULK1/MUL1/AGK/AGPAT5/MAOB/PSEN1/SH3GLB1/CYP27B1/GUCY2D/BAD/MOAP1/TOMM5/NLRX1/RNF185/CNP/VAMP1/VDAC3/MARC2/MTOR/NAV3/SNCA/SIGMAR1/BAK1/MSTO1/BCL2L2/SLC8A3/GJA1/SNN/TOMM34/MGARP/FOXO3/FUNDC1/PI4KB	105
CC	GO:0031970	organelle envelope lumen	52/7377	88/19717	2.904e-05	0.0004323	0.0003093	ALOX5/LYN/PINK1/TXNIP/AIFM1/SOD1/CAPN2/PANK2/NDUFA8/PRELID1/AK2/COX19/CMC4/HTRA2/FGR/CAT/IGF2R/CPOX/TIMM8B/UQCC2/GATM/CHCHD10/FBXL4/CHCHD7/NLN/TIMM10B/SHMT2/NME4/SIRT5/REXO2/SUOX/COA7/THEM4/COA6/MICU1/BLOC1S1/CACYBP/NDUFS1/COA4/AGK/PRELID2/CHCHD2/DIABLO/THOP1/TRIAP1/APP/SNCA/PNPT1/ARL2BP/MICU2/CIAPIN1/TIMM9	52
CC	GO:0005741	mitochondrial outer membrane	93/7377	178/19717	3.691e-05	0.0005391	0.0003856	BMF/VAT1/PINK1/HADHB/ARMCX1/GPAM/PPP1R15A/PMAIP1/BCL2A1/CISD2/ACSL5/GK/GDAP1/AIFM2/FAM210B/MIEF1/FIS1/CYB5B/BRI3BP/CYB5A/MCL1/ABCB6/MAOA/ACSL4/IFI27/RSAD2/CASP8/RHOT2/ACACB/STARD7/RAF1/MAVS/LRRK2/RAB32/DAO/AGPAT4/ARMCX3/DDX3X/MTX1/BPHL/ACSL6/LETMD1/BCL2L11/MGST1/ARMCX2/BCL2/BAX/SLC25A46/PPP2R2B/TOMM22/TOMM40L/NME1/QTRT1/UBC/TOMM40/CPT1A/VDAC2/USP30/CISD1/CYB5R3/DNM1L/TOMM20/VDAC1/PPP1CC/ULK1/MUL1/AGK/AGPAT5/MAOB/SH3GLB1/CYP27B1/BAD/MOAP1/TOMM5/NLRX1/RNF185/CNP/VAMP1/VDAC3/MARC2/MTOR/SNCA/BAK1/MSTO1/BCL2L2/SLC8A3/GJA1/SNN/TOMM34/MGARP/FOXO3/FUNDC1/PI4KB	93
CC	GO:0035578	azurophil granule lumen	53/7377	91/19717	4.264e-05	0.0006112	0.0004372	FUCA1/HEXB/RNASE2/VAT1/GRN/CTSA/AZU1/RETN/MNDA/GM2A/NPC2/CREG1/PLAC8/CTSC/ACTR2/STK11IP/ARSB/RNASE3/FTL/MAN2B1/PRKCD/GCA/IMPDH1/CAP1/GNS/ACLY/GDI2/SDCBP/AGA/GLA/NHLRC3/GUSB/PRDX6/TOLLIP/UNC13D/DSN1/IST1/FRK/CYB5R3/CCT8/FABP5/ARSA/MAPK1/FUCA2/CTSG/C6orf120/VCP/ANXA2/PRTN3/PSMD1/MPO/PA2G4/PRSS2	53
CC	GO:0030027	lamellipodium	99/7377	193/19717	5.493e-05	0.000773	0.000553	MYO1G/VASP/RAC2/DPYSL3/APBB1IP/SNX1/TSC1/ARHGAP31/FAM89B/SPATA13/SH3RF1/NEDD9/ARAP3/KITLG/CIB1/FLOT1/ALS2/CD44/PSTPIP1/FGD6/FGD5/SLC9A1/TESC/PKD2/IQGAP2/ACTR2/PTPRO/PTPN13/DPP4/EVL/DOCK8/TWF2/PLEK2/RDX/PARVB/CTNNA1/PAK1/PTK2B/MCC/SWAP70/CORO1A/CAPG/ITSN1/ACTC1/CDK5/ARHGEF6/TUBB3/CSPG4/AIF1/ACTA2/SH3BP1/RAC1/ARPIN/CCDC88A/KPTN/CYFIP1/FLOT2/CORO1B/PTK2/SYNE2/SRGAP2/CTNNA3/ABLIM3/PLXND1/MEFV/DNM2/CFL1/FER/CORO1C/KCNA2/ACTR3/PXN/MYLK/UNC5C/PKN2/FSCN1/ABI3/MYO10/RUFY3/FGD3/NHS/PHACTR4/FGD4/ENAH/NRBP1/ARPC2/RHOA/TRPV4/APP/DAG1/PDLIM4/ITGB1BP1/SSH1/AMOTL1/ACTA1/INPPL1/NCKAP1/PTPRM/ABLIM1	99
CC	GO:0005743	mitochondrial inner membrane	218/7377	473/19717	5.804e-05	0.0008022	0.0005739	SCO2/SLC27A1/LYN/PINK1/HADHB/C15orf48/CHCHD6/AIFM1/CYP27A1/TIMM23B/SLC25A37/IMMP1L/STAT3/SLC25A19/MRPS6/UQCRC2/SLC25A25/FECH/SIRT4/SLC25A20/CDS2/COX11/YME1L1/UQCR11/NDUFA8/SPNS1/PTPMT1/MPV17/SLC25A28/MRPL35/ALDH18A1/MRPL45/CPT2/HIGD1A/NDUFC1/UQCC1/MRS2/CLPX/COQ7/TMEM70/COQ5/DUSP18/CHCHD1/NDUFB11/APOO/NDUFAF4/MRPL40/MCU/MRPS30/MRPL34/NDUFS3/FGR/COX20/NDUFA3/DNAJC19/RSAD2/OMA1/DNAJC30/CPOX/TIMM8B/UCP2/TMEM14C/MRPS16/GUF1/UQCC2/TIMM17A/NDUFA11/ETFDH/SLC25A10/MPC2/GATM/COQ3/MRPS14/CHCHD10/MRPL54/ABCB10/CLU/TIMM21/UQCR10/GRPEL1/SLC25A15/BDH1/COX7C/AFG3L2/MRPL44/SLC25A5/LRRK2/MRPL33/TIMM10B/EFHD1/COX7A2L/NDUFA4/IMMP2L/CRLS1/SLC25A12/LETMD1/GRPEL2/SHMT2/NME4/LETM2/COX4I2/NDUFA1/NDUFAF3/SIRT5/WDR93/MRPL51/COX16/THEM4/COQ10B/OXA1L/COQ9/SFXN1/COX15/TOMM40/TYMS/SLC25A35/NDUFA10/MRPL49/COQ6/MICU1/NDUFB1/MRPL3/NOA1/PET100/ACADVL/NDUFB5/UQCRQ/GOT2/HADHA/UCP1/MRPL42/NDUFS1/DAP3/COA3/TIMM22/SLC25A33/SLC25A47/MRPS34/SLC25A13/AGK/NDUFB8/LETM1/SLC25A26/PSEN1/DNAJC15/MRPL4/SLC25A51/SURF1/MRPS33/PARL/SLC25A16/TMEM126A/NDUFB6/MRPL20/FPGS/MRPL46/MICU3/MRPS18B/TIMMDC1/MRPL24/L2HGDH/MRPL36/SLC25A24/MRPS25/NDUFB3/PMPCB/CNP/SDHA/MRPS15/SLC25A45/MRPL48/NDUFS7/NDUFAF2/NDUFV2/ND4/SDHD/AURKAIP1/TAZ/MRPL41/SNCA/COQ10A/UQCRB/SLC25A22/SLC9B2/SLC25A32/COQ4/SFXN4/MRPL2/NDUFB2/SLC25A38/MPV17L2/MRPS2/TIMM50/SLC25A39/CHDH/MRPS9/COX6C/PGS1/ENDOG/APOOL/ECSIT/NNT/NDUFS2/MTCH2/ABCB7/MTFP1/TIMM44/CKMT2/SMIM20/MICU2/NDUFA7/MRPL30/TMEM126B/TIMM9/MRPL1/MRPS17/TMEM177/COX7B	218
CC	GO:0016363	nuclear matrix	61/7377	109/19717	6.115e-05	0.0008304	0.000594	ALOX5/LMNB1/VIM/ENC1/CEBPB/JAK2/HAT1/UHRF1/CENPW/MORC2/ZNF326/CFL2/PRKCD/MBD1/RUVBL2/RUVBL1/ARFGEF1/YEATS4/PSPC1/HNRNPA2B1/RGS12/GMCL1/TEP1/SATB2/KAT8/PML/KIF4A/CSNK2B/XPOT/SMARCAD1/SFPQ/ATXN7/CLIC4/SCAF8/SPARC/AKAP8/ZNF703/PRPF40A/YY1/CFL1/RNASEL/CHMP1A/SRPK1/KRT8/HNRNPM/ATXN3/NSMF/DNMT3A/SRRM1/SMC3/CAD/NUFIP1/ATXN1/TGFB1I1/DCAF7/MEN1/STAG1/POLA1/PRKCZ/PAXIP1/ERCC8	61
CC	GO:0005874	microtubule	194/7377	416/19717	6.385e-05	0.000842	0.0006023	CRHBP/SLC8A1/KLHL21/TUBA1A/DPYSL2/NINL/BCL10/STMN1/MAP1S/DNM3/STAU2/KCNAB2/KLC1/RAB11A/TUBB6/DYNC1LI1/EML4/ODF2/NICN1/TTLL4/HAUS8/KIF9/TUBB2A/PSRC1/KIF3B/NEIL2/KIFAP3/MAP1LC3A/MAP4/CLIP1/MYO5A/DYNLL2/RASSF5/SYNJ1/CSNK1D/ROR2/CENPE/BAIAP2/SCTR/EML3/KIFC3/CDK5/SVIL/APPBP2/KLHL22/PAFAH1B1/TUBB3/CDK5RAP2/EMD/TUBD1/ARHGEF2/KIF4A/MAPRE1/SKA2/SPAG5/CDK2AP2/TPPP3/HOOK2/NDRG1/MAPRE2/KIF2A/DNAL1/CYLD/MAP1LC3C/ASPM/ZNF207/SERP1/BICD1/KIF16B/TBCB/HAUS2/AKNA/DNM1/DCLK2/DISC1/HOOK3/MEFV/DNM2/TUBA1C/BOD1L1/DNAI2/TUBA4B/BCAS3/RGS14/KIF24/DNAH17/TUBGCP3/KIF20B/CKAP5/DCTN2/JAKMIP1/DYNC2LI1/TUBA4A/NDEL1/GAS2L3/MAP2K2/MAP3K11/KIF13A/NUSAP1/INCENP/ZW10/TMEM214/TTLL3/CCT4/DYNLRB1/DYNLRB2/DNM1L/KIF27/RASSF3/DYNLT3/KATNA1/TUBG2/CLASP2/CCT8/TTLL11/TBCC/DNAL4/TUBGCP5/FAM161A/CAPN6/CEP57/RCC2/TBCA/MID2/BAG2/HAUS5/CEP170B/TUBB4A/SPRY2/HAUS1/DVL1/KATNAL1/MAP1A/TUBAL3/SS18/TTLL1/DNAI1/KIF2C/KIF17/TUBB1/TPGS1/KATNB1/TUBA1B/FAM161B/CLIP2/SNTB2/KIF1B/SKAP1/CDC27/KIF5B/SLAIN2/GABARAPL1/KLC4/EML6/DYNC1LI2/KLC2/REEP3/TBCE/POLB/DNAH10/RUSC1/MISP/KIF1C/NAV3/TRPV4/AURKA/RAB3D/NCKAP5L/KIF12/SHROOM1/BEX4/FGF13/CSPP1/SLC8A3/SPAG17/CCDC66/CYP2A6/KLC3/DNAH8/TTLL6/TTC30B/TCP11L1/NEK7/DNAH2/TPPP/RP1/KIF14/BOD1/MACF1/NUDC/PRC1/GAS8/SKA3/RMDN2	194
CC	GO:0032588	trans-Golgi network membrane	53/7377	92/19717	6.418e-05	0.000842	0.0006023	RAB9A/AP1B1/CD74/SYS1/RAB31/SCAMP2/M6PR/AFTPH/COG8/HLA-DPB1/HLA-DPA1/VAMP3/IGF2R/SCAMP1/RAB8A/ATP7B/RAB43/HLA-DRA/AP1M2/CLVS2/SCAMP4/GOLPH3L/VPS51/COG4/AP4S1/STX16/KIF13A/VPS52/ARL1/VTI1A/COG6/ARFRP1/AP4B1/AP1S3/PLD4/AP1G1/HLA-DQB2/LGR5/CALN1/COG2/COG1/RHOBTB3/TMEM79/LLGL1/AP1M1/COG7/LGR6/SCAMP5/RABEPK/PICK1/APP/CLIP3/RGP1	53
CC	GO:0031901	early endosome membrane	79/7377	149/19717	7.204e-05	0.0009293	0.0006648	FCGR1B/STAM/ANXA1/STX7/APPL2/ARF6/SNX1/FCGR1A/GPNMB/GGA2/STEAP4/WDR91/WLS/WDR81/RAB31/LDLRAD4/GRIPAP1/ZFYVE28/HLA-F/CMTM6/NAPEPLD/SNX20/HLA-E/HLA-B/FIG4/EHD4/CLCN3/PMEPA1/PML/EHD1/HLA-G/OCRL/EPHA8/CLVS2/ARC/SNX27/HLA-C/KIF16B/SNX6/DTX3L/SPHK1/SH3GL1/MTMR4/RAB5C/TSG101/SORCS2/RAB5A/SNX13/HGS/MTMR2/INPP5F/CD274/RABGEF1/FZD5/ABCA7/RABEP1/EGFR/KIR2DL4/RCC2/PSEN1/CLCN4/SNX5/STX12/VTI1B/HLA-A/SNX21/HPS6/EPHB1/LLGL1/SNX19/MMGT1/SNX4/VAC14/CLIP3/PDLIM4/MCOLN3/SNX16/APPL1/NTRK2	79
CC	GO:0055037	recycling endosome	91/7377	176/19717	7.381e-05	0.0009348	0.0006687	TUBA1A/STX7/ARF6/SLC9A9/SYT11/RAB11A/PACSIN2/ACKR3/ABHD17C/HFE/TNF/SLC31A2/PDIA3/RAN/SCAMP2/CD22/GRIPAP1/MYO5A/RAP2C/HLA-F/MICALL1/CMTM6/PLEKHB2/ATP11B/ITSN1/HLA-E/HLA-B/FIG4/VAMP3/EHD4/SCAMP1/FCHSD1/TMEM230/RAP2B/RAB11FIP4/RNF11/EHD1/RAB8A/NISCH/HLA-G/RAC1/DENND6B/NDRG1/RAB29/C1orf210/SLC9A7/HLA-C/MLC1/ATG9A/TBC1D17/SCAMP4/VPS51/MICALL2/ABCG1/UNC13D/SORCS2/VIPAS39/ACAP1/INPP5F/CD274/VPS52/RFFL/RABGEF1/MCOLN2/COMMD1/RAB8B/RABEP1/ULK1/TFRC/AP1G1/RAB35/STX12/ZDHHC2/VTI1B/HLA-A/LMTK2/STX8/EHD3/GPR161/FZD7/VPS16/OPTN/SYT5/SCAMP5/DENND6A/APP/CLIP3/PDLIM4/SLC30A10/ACKR2/FCHSD2	91
CC	GO:0031965	nuclear membrane	143/7377	296/19717	7.488e-05	0.0009348	0.0006687	MYOF/ALOX5/LMNB1/TRA2B/GCH1/SUN2/CLIC1/ALOX5AP/LMNA/C9orf72/STAT6/NUP62/GAPDH/KLHDC2/PRPF38A/SHISA5/CERS2/RETSAT/P2RX7/QSOX2/ZNF383/TMEM43/GRK5/CCND2/TMC8/NRM/NUCB2/CDK4/ITPR1/UNC50/NUP85/GTPBP4/NUDT1/GNAQ/PAK1/SCRN1/PCM1/INTS5/ZBTB1/KPNA4/CERS5/DUSP2/ATP11B/PHF11/PNPLA7/RNF13/TMEM109/IFI27/YEATS4/ABL1/PAFAH1B1/CCDC155/EMD/DNAJC2/DDX19B/TXNL4A/SDCBP/POM121/C2orf42/TMEM18/SIRT1/CERS4/TOR1B/TMEM97/THAP7/DPY19L4/CLMN/DNAJC1/RCC1/TFPT/CREB3L4/TM7SF2/ZNF224/SUMO1/PUM2/PSEN2/SYNE2/AEN/TOR1A/IL15RA/SCAI/ZNF354C/P2RX1/BCL2/TMEM201/TBC1D20/EI24/ANKRD17/CBX3/MX1/MAD2L1BP/NUP107/PHF20/MLX/SLC29A2/CPTP/ZMPSTE24/NPIPA1/DTL/NSMF/INTS2/PLCB1/EGFR/NUP93/PLCD4/EPC1/ZC3HC1/CPNE1/PSEN1/NUP205/APEH/DPY19L2/GTF3C3/GUCY2D/SPAG4/ATP1B4/NUP50/NOC4L/INA/MCM3AP/TMEM38B/LEMD3/NPAP1/MTDH/HPN/NAV3/ERN1/SNCA/P2RX2/SIGMAR1/ALG14/KPNB1/CMTM3/DCTN5/ACKR2/HOXA7/POM121C/DPY19L2P2/AAAS/POMZP3/P2RX5/GCHFR/RRP12	143
CC	GO:0005775	vacuolar lumen	89/7377	172/19717	8.492e-05	0.001043	0.0007463	FUCA1/ASAH1/HEXB/RNASE2/VAT1/VCAN/GRN/PLBD2/CTSA/AZU1/RETN/MANBA/CTSF/MNDA/TPP1/CTSD/NAGLU/GM2A/NPC2/CREG1/PLAC8/LIPA/CTSS/CTSC/IDS/LGMN/LAMP2/CTSK/PSAP/CD1E/CD74/HEXA/ACTR2/STK11IP/CHID1/ARSB/RNASE3/SGSH/FTL/GALC/MAN2B1/PRKCD/GCA/IMPDH1/CAP1/GNS/ACLY/EPDR1/CSPG4/GDI2/SDCBP/CTSB/AGA/GLA/IDUA/NHLRC3/GUSB/HPSE/PRDX6/TOLLIP/UNC13D/DSN1/IST1/CTSV/FRK/BCAN/CYB5R3/CCT8/FABP5/ARSA/GPC2/MAPK1/GAA/FUCA2/NEU1/SMPD1/CTSG/C6orf120/GPC4/VCP/ANXA2/PRTN3/SDC3/DAPK2/PSMD1/MAN2B2/MPO/PA2G4/PRSS2	89
CC	GO:0031248	protein acetyltransferase complex	54/7377	95/19717	9.03e-05	0.001075	0.0007692	ZZZ3/DR1/ENY2/MORF4L2/SUPT7L/KAT2B/MRGBP/ACTB/JADE3/NAA20/RUVBL2/ATXN7L3/RUVBL1/EPC2/MBIP/MSL3/NAA10/KAT7/YEATS4/TAF5L/KAT8/TAF12/BRD8/NAA38/TAF5/MCRS1/KAT5/BRPF1/DPF2/RSF1/PHF20/TAF6L/NAA16/ING3/KANSL1L/EPC1/KAT2A/PHF10/TAF9B/TAF4/OGT/ING4/JADE1/NAA15/USP22/MSL1/UBAP2L/POLE4/TADA3/ACTL6A/KAT6B/WDR5/SUPT20H/TAF7	54
CC	GO:1902493	acetyltransferase complex	54/7377	95/19717	9.03e-05	0.001075	0.0007692	ZZZ3/DR1/ENY2/MORF4L2/SUPT7L/KAT2B/MRGBP/ACTB/JADE3/NAA20/RUVBL2/ATXN7L3/RUVBL1/EPC2/MBIP/MSL3/NAA10/KAT7/YEATS4/TAF5L/KAT8/TAF12/BRD8/NAA38/TAF5/MCRS1/KAT5/BRPF1/DPF2/RSF1/PHF20/TAF6L/NAA16/ING3/KANSL1L/EPC1/KAT2A/PHF10/TAF9B/TAF4/OGT/ING4/JADE1/NAA15/USP22/MSL1/UBAP2L/POLE4/TADA3/ACTL6A/KAT6B/WDR5/SUPT20H/TAF7	54
CC	GO:0000123	histone acetyltransferase complex	49/7377	85/19717	0.0001168	0.001352	0.0009672	ZZZ3/DR1/ENY2/MORF4L2/SUPT7L/KAT2B/MRGBP/ACTB/JADE3/RUVBL2/ATXN7L3/RUVBL1/EPC2/MBIP/MSL3/KAT7/YEATS4/TAF5L/KAT8/TAF12/BRD8/TAF5/MCRS1/KAT5/BRPF1/DPF2/RSF1/PHF20/TAF6L/ING3/KANSL1L/EPC1/KAT2A/PHF10/TAF9B/TAF4/OGT/ING4/JADE1/USP22/MSL1/UBAP2L/POLE4/TADA3/ACTL6A/KAT6B/WDR5/SUPT20H/TAF7	49
CC	GO:0001891	phagocytic cup	20/7377	27/19717	0.0001181	0.001352	0.0009672	MYO1G/ANXA1/MCOLN1/SYT11/TNF/RAB31/ARHGAP25/CORO1A/TLR4/CDC42SE2/AIF1/SH3BP1/BIN2/ARHGAP12/LCP1/DNM2/TRIP10/ABCA7/SNX5/MEGF10	20
CC	GO:0035577	azurophil granule membrane	36/7377	58/19717	0.0001188	0.001352	0.0009672	FPR1/AZU1/MANBA/RAP1B/ATP8A1/CKAP4/ACPP/LAMP2/PSAP/LAMP1/ATP6V0C/SLCO4C1/CD63/CMTM6/ATP11B/LAMTOR1/C3AR1/VNN1/ARL8A/MGST1/TOM1/RAB5C/BRI3/GLIPR1/NFAM1/CPNE1/PSEN1/GAA/CPNE3/TMEM30A/SNAP29/RAB3D/B4GALT1/LPCAT1/CEACAM8/DDOST	36
CC	GO:0061695	transferase complex, transferring phosphorus-containing groups	126/7377	259/19717	0.0001332	0.001494	0.001069	CDKN2D/CDKN1A/SOCS3/ACVR2B/MAD2L2/C9orf72/CCND3/PFKM/PFKP/CHRAC1/SIK1/ATG14/PAF1/CISH/ERCC4/PIK3R3/CCND2/TBC1D5/PKM/CDK4/ZBTB7A/SOCS5/INSR/IKBKG/GTF2E1/PRPSAP1/CCNG1/SOCS6/IGF1R/CDK5/SETD5/TAF5L/PRIM2/CCNH/POLD4/TAF11/TAF12/GTF2F2/SIK2/PIK3R6/POLD2/ATG13/POLR2L/PHKB/CCND1/SOCS7/ACVR1B/CDK9/TAF5/RPRD1B/IFIT5/PHKG1/POLR2H/GTF2H4/ZNFX1/PRKAG2/POLG/LAS1L/BCCIP/CCNE1/PFKFB1/PCNA/RPRD2/ERCC1/PIK3CD/CCNK/PRPS1/GTF2F1/POLR1C/POLR2F/MAP3K5/POLR2D/LEO1/TAF6L/CDK5R2/ULK1/CCNY/TBPL1/POLR3E/KAT2A/GTF2A1/PRKAA1/POLR2K/CCNA1/SMCR8/SOCS1/ERCC2/TAF9B/POLD1/PRPS1L1/TAF4/PRKAG1/RPAP2/PRPS2/RB1/CCNA2/PIK3CG/POLA1/POLA2/SLA2/TERT/POLRMT/POLR2J2/TBP/CD3EAP/CCNT1/POLR3F/CDC73/ERN1/VAC14/NRBF2/CCNG2/POLR3GL/POLE4/CCNB3/CHUK/TADA3/PFKL/POLR2I/SOCS2/SESN2/POLR3K/CCNF/PIK3CB/TAF7/PRKAB1	126
CC	GO:0031093	platelet alpha granule lumen	40/7377	67/19717	0.0001726	0.001908	0.001365	IGF1/SERPINA1/FN1/F5/PROS1/VEGFB/ACTN4/PPBP/A2M/TGFB1/SCCPDH/HGF/MAGED2/ACTN1/FAM49B/CFD/QSOX1/VEGFA/TEX264/ALDOA/CLU/SERPING1/PCYOX1L/PDGFB/SPARC/SERPINE1/TIMP1/PDGFA/VWF/NHLRC2/A1BG/SRGN/VTI1B/TGFB3/HRG/TOR4A/APP/APOOL/SERPINF2/ALB	40
CC	GO:0031228	intrinsic component of Golgi membrane	39/7377	65/19717	0.0001787	0.001948	0.001393	SGMS2/ZDHHC20/MAN1C1/LFNG/QSOX2/SYS1/ZDHHC9/UNC50/CHST2/CSGALNACT1/QSOX1/SAMD8/FURIN/SLC35B4/BET1/SLC39A13/CHST5/TVP23C/TEX261/IER3IP1/TVP23B/PCSK7/TBC1D20/SGMS1/B4GALNT1/CSGALNACT2/PCSK5/TVP23A/SLC35B1/SLC35A3/SLC35A5/ACER3/CHST12/YIF1B/YIF1A/SYT4/RER1/ERGIC2/SLC35A2	39
CC	GO:0031519	PcG protein complex	30/7377	47/19717	0.0002121	0.00228	0.001631	PHF19/EZH2/CBX6/RYBP/CSNK2A2/TRIM37/PHC2/PCGF2/PCGF1/PCGF3/RBBP7/CBX7/RBBP4/CSNK2B/SIRT1/HDAC2/DNMT3L/KDM2B/YY1/ASXL2/CBX4/RING1/PHC1/AEBP2/SCML2/BAP1/ASXL3/ZFP42/UBAP2L/EZH1	30
CC	GO:0031091	platelet alpha granule	51/7377	91/19717	0.0002263	0.0024	0.001717	IGF1/SERPINA1/FN1/F5/PROS1/VEGFB/CYB5R1/ACTN4/PPBP/A2M/TGFB1/STXBP1/PHACTR2/SCCPDH/HGF/MAGED2/CD36/ACTN1/FAM49B/CFD/QSOX1/VEGFA/TEX264/ALDOA/TREML1/CLU/SERPING1/PCYOX1L/PDGFB/SPARC/SERPINE1/TIMP1/SYTL4/PDGFA/VWF/NHLRC2/A1BG/SRGN/VTI1B/TGFB3/HRG/LHFPL2/TMX3/TOR4A/STXBP3/APP/SNCA/APOOL/SERPINF2/ALB/CD109	51
CC	GO:1905368	peptidase complex	50/7377	89/19717	0.0002398	0.002508	0.001794	PSMB9/PSMB8/ENY2/PSMA5/RAD23B/PSMD11/PSME1/UBE3A/ZFAND2A/PSMB10/HSPB1/PSMA1/PSMA4/ATXN7L3/HTRA2/PSMB1/PSMC4/ADRM1/TAF12/PSMD13/PSMB3/AFG3L2/UCHL5/PSMB5/PSMD6/PSMC3/PAAF1/PSME3/PSMC6/SPCS2/TAF6L/UBR1/PSMC1/TAF9B/PSMD8/PSMA2/F3/PSMC5/PSMC2/PSMB2/PSMD4/VCP/SEC11A/USP22/PSMD1/TADA3/PSMB4/PSMD9/PSMD3/SUPT20H	50
CC	GO:0030136	clathrin-coated vesicle	94/7377	188/19717	0.0002738	0.002826	0.002022	NRGN/FCGR1B/FCGR1A/WNT5A/ECE1/GGA2/FCHO1/AP1B1/FCHO2/DENND1A/BCAP31/DVL2/CD74/APOE/TBC1D5/M6PR/VPS41/IL7R/DENND1B/SLC2A8/SH3BP4/AFTPH/ROR2/SNX18/HLA-DPB1/HLA-DPA1/GOPC/VAMP3/IGF2R/SCAMP1/TMED10/CLTB/FURIN/NUMB/VPS33A/CD3D/LDLR/LRP1/WIPI1/RAB8A/RGS19/OCRL/HLA-DRA/AP1M2/AP1G2/CLVS2/CTLA4/CLTCL1/AP2A2/GPR107/VPS18/DNM2/UNC13D/RAB5A/KIAA1107/ADRB2/AP2S1/CD3G/ABCB4/INPP5F/VTI1A/NECAP2/FZD5/VWF/CHRM2/AP2A1/LMBRD1/CEMIP/RAB8B/EGFR/MALL/AP3B1/FZD4/TFRC/DVL1/AP1G1/ASTN2/RAB3A/HLA-DQB2/RAB35/SYT9/ATP7A/AP1M1/SYT1/HBEGF/CD4/SYT2/VPS16/AP2M1/SNX9/FZD2/PICALM/RAB27A/AVPR2	94
CC	GO:1905369	endopeptidase complex	38/7377	64/19717	0.0002913	0.002941	0.002104	PSMB9/PSMB8/PSMA5/RAD23B/PSMD11/PSME1/UBE3A/ZFAND2A/PSMB10/HSPB1/PSMA1/PSMA4/HTRA2/PSMB1/PSMC4/ADRM1/PSMD13/PSMB3/UCHL5/PSMB5/PSMD6/PSMC3/PAAF1/PSME3/PSMC6/UBR1/PSMC1/PSMD8/PSMA2/PSMC5/PSMC2/PSMB2/PSMD4/VCP/PSMD1/PSMB4/PSMD9/PSMD3	38
CC	GO:0005767	secondary lysosome	12/7377	14/19717	0.0002926	0.002941	0.002104	CRHBP/NCOA4/SQSTM1/LAMP2/ADAM8/LAMP1/MAP1LC3A/FTL/NCF4/NCF2/NCF1/LRRK2	12
CC	GO:0055038	recycling endosome membrane	46/7377	81/19717	0.0003001	0.002978	0.00213	ARF6/RAB11A/PACSIN2/ABHD17C/PDIA3/SCAMP2/GRIPAP1/RAP2C/HLA-F/MICALL1/CMTM6/PLEKHB2/ATP11B/HLA-E/HLA-B/VAMP3/EHD4/SCAMP1/RAP2B/RAB11FIP4/EHD1/RAB8A/HLA-G/RAC1/NDRG1/SLC9A7/HLA-C/SCAMP4/SORCS2/ACAP1/CD274/RFFL/MCOLN2/RAB8B/RAB35/STX12/ZDHHC2/VTI1B/HLA-A/EHD3/FZD7/OPTN/SYT5/SCAMP5/CLIP3/PDLIM4	46
CC	GO:0030133	transport vesicle	180/7377	392/19717	0.0003084	0.003022	0.002162	IGF1/NRGN/SLC40A1/CTTNBP2/APBA1/RAB9A/DPYSL3/STX7/CD55/STX11/APH1B/SYT11/ERP29/MCFD2/HCK/RAB11A/CHP1/KLHL12/SYTL1/PLIN3/SEC22B/STXBP5/LAMP1/CD59/CD74/WDR7/SCAMP2/M6PR/SLC2A8/SYPL1/ITPR1/UNC13B/AFTPH/SGTA/SAR1B/WFS1/TMEM187/HLA-F/RABAC1/CNIH3/COPE/TPRG1L/HLA-DPB1/HLA-DPA1/GOPC/HLA-E/CRISPLD2/HLA-B/VAMP3/PDE4B/CLCN3/IGF2R/SCAMP1/SYNGR2/TMEM230/C16orf70/TMED10/CLTB/DTNBP1/FURIN/CLN3/SEMA4C/CNST/BLOC1S6/ANKRD27/BET1/RAB8A/PRG2/HLA-G/CCDC88A/GOSR2/HLA-DRA/LRRK2/AP1G2/GOSR1/SYT6/CLTCL1/STX5/PSEN2/HLA-C/SAR1A/SCG3/ATG9A/ROGDI/TOR1A/PAM/CPA3/KDELR3/DNM1/DISC1/RPH3AL/BLOC1S3/SCAP/COPG2/GOLGA5/UNC13D/RAB5A/COPA/KIAA1107/NDEL1/SYTL4/STX16/MTMR2/KDELR2/SSPN/LMAN1/VDAC2/NKD2/VTI1A/PEF1/PTPRN2/SREBF2/SLC17A5/YKT6/DNM1L/AP2A1/VDAC1/FGFRL1/SEC23IP/RAB8B/ARCN1/ICA1/SYT13/AP1G1/VMA21/PSEN1/SYNGR3/SYNGR4/RAB3A/HLA-DQB2/EXOC3L1/RAB35/STX12/SYPL2/VTI1B/SYT9/SYTL2/SNTB2/HLA-A/ZNRF1/ATP7A/COPZ2/SYT1/TMEM30A/OPRD1/RAB3B/DBH/SYT2/VAMP1/DOC2A/SYT4/SNCAIP/SYT5/SCAMP5/RABEPK/PICK1/BRSK1/APP/RAB3D/SNCA/SLC9B2/ATP6V1B1/AZIN2/APH1A/SPX/PICALM/SYCN/SEC24A/SYN3/RAB27A/RAB26/BIN1/AMPH/GALNT15/SEC31B/TMEM168/SEC16B/DMXL2/LGI3/SV2B	180
CC	GO:0030173	integral component of Golgi membrane	36/7377	60/19717	0.0003135	0.003033	0.002169	SGMS2/ZDHHC20/MAN1C1/LFNG/QSOX2/SYS1/UNC50/CSGALNACT1/QSOX1/SAMD8/FURIN/SLC35B4/BET1/SLC39A13/TVP23C/TEX261/IER3IP1/TVP23B/PCSK7/TBC1D20/SGMS1/B4GALNT1/CSGALNACT2/PCSK5/TVP23A/SLC35B1/SLC35A3/SLC35A5/ACER3/CHST12/YIF1B/YIF1A/SYT4/RER1/ERGIC2/SLC35A2	36
CC	GO:0030662	coated vesicle membrane	91/7377	182/19717	0.0003395	0.003244	0.002321	NRGN/FCGR1B/FCGR1A/WNT5A/MCFD2/FCHO1/KLHL12/AP1B1/FCHO2/DENND1A/SEC22B/CD59/CD74/APOE/TBC1D5/M6PR/IL7R/SLC2A8/AFTPH/SAR1B/ROR2/HLA-F/CNIH3/COPE/HLA-DPB1/HLA-DPA1/HLA-E/HLA-B/VAMP3/IGF2R/ARFGAP3/TMED10/CLTB/CD3D/LDLR/HLA-G/GOSR2/HLA-DRA/AP1M2/AP1G2/CLTCL1/STX5/HLA-C/SAR1A/KDELR3/AP2A2/SCAP/COPG2/RAB5A/COPA/KIAA1107/ADRB2/AP2S1/CD3G/KDELR2/LMAN1/VTI1A/NECAP2/PEF1/SREBF2/FZD5/CHRM2/AP2A1/CEMIP/SEC23IP/EGFR/ARCN1/AP3B1/FZD4/TFRC/AP1G1/VMA21/RAB3A/HLA-DQB2/RAB35/VTI1B/SYT9/HLA-A/AP1M1/COPZ2/SYT1/HBEGF/CD4/SYT2/AP2M1/FZD2/PICALM/SEC24A/AVPR2/SEC31B/SEC16B	91
CC	GO:0000502	proteasome complex	37/7377	63/19717	0.0004703	0.00444	0.003176	PSMB9/PSMB8/PSMA5/RAD23B/PSMD11/PSME1/UBE3A/ZFAND2A/PSMB10/HSPB1/PSMA1/PSMA4/PSMB1/PSMC4/ADRM1/PSMD13/PSMB3/UCHL5/PSMB5/PSMD6/PSMC3/PAAF1/PSME3/PSMC6/UBR1/PSMC1/PSMD8/PSMA2/PSMC5/PSMC2/PSMB2/PSMD4/VCP/PSMD1/PSMB4/PSMD9/PSMD3	37
CC	GO:0030496	midbody	86/7377	173/19717	0.0006153	0.005738	0.004105	KLHDC8B/KLHL13/ZFYVE26/USP3/ARF6/NUP62/LAP3/GNAI3/ZNF330/RASGEF1B/KEAP1/SHCBP1/VPS37B/RAN/MICAL1/CHMP4B/CNTRL/PSRC1/KIF3B/EXOC1/RDX/SCCPDH/PITPNM1/CENPE/CAPG/HSPA5/SVIL/GDI1/JTB/ALKBH4/DTNBP1/RAB11FIP4/KIF4A/SPAG5/RAB8A/CEP44/TBCK/CTDP1/CYLD/FLCN/NAT10/ASPM/CLIC4/CENPC/MBD5/KLHL9/CHAMP1/CEP55/ARL8A/MAK/CCDC69/YPEL5/DNM2/GNAI2/TSG101/NTNG2/KIF20B/TRIOBP/IST1/KIF13A/INCENP/VPS4B/TTC28/KATNA1/PPP1CC/PKN2/RCC2/HSP90B1/SH3GLB1/KATNB1/EXOC4/PIN1/ANXA2/RHOA/TOPORS/AURKA/SSH1/ARL2BP/CHMP1B/ZFYVE19/KIF14/PTCH1/PRC1/EXOC2/ARL8B/PIK3CB	86
CC	GO:0031463	Cul3-RING ubiquitin ligase complex	24/7377	37/19717	0.0006417	0.005912	0.004229	KLHL21/KLHL13/KLHL24/ENC1/KLHL12/KEAP1/KLHL41/KLHL15/KCTD17/KCTD10/KLHL22/KLHL8/GLMN/RNF7/KLHL9/KBTBD8/PEF1/KLHL40/SPOPL/KLHL25/KCTD5/DEPDC5/RBX1/KLHL42	24
CC	GO:0005681	spliceosomal complex	91/7377	185/19717	0.000677	0.006164	0.00441	TRA2B/PRPF4/PRPF38A/HNRNPR/HNRNPH1/ALYREF/PPIL1/HNRNPH3/MAGOHB/API5/AKAP17A/ZNF830/CWF19L2/LSM5/CRNKL1/WDR83/HNRNPK/SYF2/SNRNP25/SNRNP200/CWF19L1/HNRNPA1/CACTIN/HNRNPA2B1/RBM8A/SNRPB/TXNL4A/U2AF1/LUC7L/SNRPA1/RNF113A/BCAS2/BUD31/DHX8/RBM41/PDCD7/RBMXL1/SCAF8/LSM7/SNIP1/RBM3/SNRPD1/PRPF3/SNRPA/SNRPC/ZCCHC8/MFAP1/ISY1/CWC22/SNRPB2/HNRNPC/IVNS1ABP/PRPF40B/PRPF40A/LUC7L2/SREK1/SNRPF/RALY/CDC40/PRPF8/SF3A3/CWC25/SMNDC1/SF3B4/AAR2/HNRNPM/PRPF31/U2AF1L4/RBMX2/SART1/SRRM1/DHX38/HNRNPA3/SUGP1/GPKOW/PRPF19/CCDC12/PRPF39/SNRPN/ZCRB1/AQR/ADAR/PPWD1/IK/DHX16/EFTUD2/LUC7L3/SYNCRIP/SNRPG/SNRPD2/UPF1	91
CC	GO:0005684	U2-type spliceosomal complex	49/7377	90/19717	0.0007319	0.006588	0.004712	PRPF4/PRPF38A/PPIL1/MAGOHB/LSM5/CRNKL1/SYF2/SNRNP200/RBM8A/SNRPB/TXNL4A/LUC7L/SNRPA1/RNF113A/BCAS2/BUD31/DHX8/LSM7/SNIP1/SNRPD1/PRPF3/SNRPC/MFAP1/ISY1/CWC22/SNRPB2/PRPF40B/PRPF40A/LUC7L2/SNRPF/CDC40/PRPF8/SF3A3/CWC25/SF3B4/PRPF31/RBMX2/SART1/PRPF19/CCDC12/PRPF39/SNRPN/AQR/IK/DHX16/EFTUD2/LUC7L3/SNRPG/SNRPD2	49
CC	GO:0005819	spindle	159/7377	347/19717	0.0007492	0.006665	0.004768	KLHL21/ACOT13/MAD2L2/PPP2CA/MAP1S/NUP62/DIAPH1/RAB11A/NEDD9/DYNC1LI1/EML4/ODF2/PTP4A1/SHCBP1/SPDL1/PKD2/HAUS8/PSRC1/KIF3B/NEIL2/NUP85/KIFAP3/MAP4/HSPB1/CSNK1D/CEP104/LATS1/MAPKBP1/CENPE/IKBKG/CBX1/CAPG/EML3/UBXN2B/PLK2/KLHL22/NPM1/PAFAH1B1/CDK5RAP2/CCDC155/EMD/JTB/NSFL1C/RAB11FIP4/ARHGEF2/KIF4A/MAPRE1/SPECC1L/SKA2/SPAG5/CEP44/NSUN2/TBCK/MAPRE2/KIF2A/CTDP1/CYLD/SLC25A5/ESPL1/ASPM/ZNF207/CLTCL1/MAP7D3/MYH9/ATM/CHAMP1/HAUS2/KBTBD8/ARL8A/NCOR1/MAK/PLK3/CCDC69/SPICE1/BCCIP/YPEL5/TMEM201/BOD1L1/MAP7D1/CBX3/RGS14/TUBGCP3/KIF20B/MAD2L1BP/CKAP5/DSN1/NDEL1/PPP2R3C/NUSAP1/INCENP/ZW10/VPS4B/CEP63/TTC28/DYNLT3/KATNA1/TUBG2/FRY/CLASP2/TUBGCP5/FAM161A/CAPN6/GPSM2/RCC2/CETN1/HAUS5/HAUS1/KATNAL1/KAT2A/CEP19/MAPK1/DLGAP5/CEP95/VRK1/ERCC2/SMC3/WDR60/KATNB1/TOPBP1/CDC27/EVI5/FAM110A/LATS2/CDC20/PKHD1/RB1/MAP2K5/NUDCD2/STAG1/PRPF19/TBL1X/POLB/MISP/TOPORS/AURKA/APP/KLHL42/BRCC3/AUNIP/BEX4/ARL2BP/IK/EFHC1/CSPP1/TADA3/SAC3D1/UXT/PIN4/CEP85/NEK7/KIF14/POC1B/BOD1/AAAS/ALMS1/PRC1/ARL8B/SKA3/RMDN2	159
CC	GO:0022624	proteasome accessory complex	17/7377	24/19717	0.0009158	0.008055	0.005762	PSMD11/PSME1/PSMC4/ADRM1/PSMD13/PSMD6/PSMC3/PSME3/PSMC6/PSMC1/PSMD8/PSMC5/PSMC2/PSMD4/PSMD1/PSMD9/PSMD3	17
CC	GO:0000164	protein phosphatase type 1 complex	9/7377	10/19717	0.0009503	0.008177	0.00585	PPP1R15A/SHOC2/NCK1/PPP1R15B/PPP1R3B/PPP1CC/PPP1CA/PPP1R11/PPP1CB	9
CC	GO:0005779	integral component of peroxisomal membrane	12/7377	15/19717	0.0009614	0.008177	0.00585	PEX11A/FAR2/PEX12/PEX11G/PEX16/FIS1/SLC27A2/PEX13/PEX3/FAR1/PEX11B/ABCD1	12
CC	GO:0031231	intrinsic component of peroxisomal membrane	12/7377	15/19717	0.0009614	0.008177	0.00585	PEX11A/FAR2/PEX12/PEX11G/PEX16/FIS1/SLC27A2/PEX13/PEX3/FAR1/PEX11B/ABCD1	12
CC	GO:0005884	actin filament	58/7377	111/19717	0.000995	0.008371	0.005988	SH2B2/FYN/EZR/RAC2/DPYSL3/ANXA1/PLS1/TSC1/HCK/PDLIM1/MYO9B/POTEKP/FLNA/KEAP1/PSTPIP1/TPM3/AKAP13/PKD2/HCLS1/GAS7/TWF2/PAK1/MYO5A/PDLIM7/ACTN1/CORO1A/ACTC1/PSTPIP2/AIF1/SPECC1L/RAC1/KPTN/MYO1C/CORO1B/ARHGAP6/TPM4/PDLIM5/LCP1/WIPF2/COTL1/VPS18/TPM1/MARK2/PLS3/RHOQ/CD2AP/DMTN/BIN3/GNG12/WIPF1/MISP/PDLIM4/ESPNL/WAS/ACTA1/ACKR2/NCKAP1/FMN1	58
CC	GO:0101003	ficolin-1-rich granule membrane	35/7377	61/19717	0.001189	0.009899	0.007082	FPR2/FPR1/LILRB2/LILRA3/CD55/SLC11A1/CLEC4D/CD58/MGAM/DIAPH1/DYNC1LI1/CD93/LAMP2/SLC2A3/ADAM8/LAMP1/ATP6V0C/FCAR/TCIRG1/NBEAL2/LAMTOR1/ATP6AP2/TRPM2/RAC1/CR1/ARL8A/AP2A2/CD300A/PTPRN2/GAA/TBC1D10C/SERPINB6/RHOA/ENPP4/SERPINB10	35
CC	GO:0032587	ruffle membrane	50/7377	94/19717	0.001297	0.01068	0.007641	EZR/APPL2/ITGA5/DIAPH1/SPATA13/RASGRP2/PLEKHA1/PACSIN2/CIB1/FGD5/C2CD5/TESC/TLN1/PAK1/ARF4/PLEKHO1/DDX58/FGR/AIF1/ARHGEF2/RAC1/MYO1C/IFIT5/SH3YL1/LCP1/DNM2/TPM1/INPP5K/MTMR6/NME1/THEM4/CFL1/KANK1/PLEK/CORO1C/ABCA7/CLASP2/ADAM17/SPRY2/MTMR9/PSD4/EPS8L2/RHOA/TRPV4/TIRAP/ARHGEF4/MACF1/WWC1/PSD3/PTPRJ	50
CC	GO:0016607	nuclear speck	178/7377	397/19717	0.001323	0.01078	0.007713	EPAS1/NFKBIZ/NAMPT/NR4A2/NSRP1/LMNA/NXF1/SRSF5/CCNL1/BARD1/CKAP4/LPXN/ASCC3/DUSP10/PRPF4/PACSIN2/TAP2/ZC3H14/CHTOP/ZNF217/IL15/ALYREF/GRK5/RNPS1/THRAP3/DENND1B/MPP1/API5/PCBP1/SMC5/TKT/SARNP/AKAP17A/NXT1/HIF1A/SRSF10/ZNF830/TRIM22/SMC6/CRNKL1/METTL3/ACADM/RBBP6/MBD1/CBY1/YTHDC1/RBM4/RBM4B/S100PBP/SYF2/HABP4/HSF4/TCF12/RMI2/FAM76B/PSKH1/TOE1/TAF5L/PSPC1/CACTIN/FIBP/RBM8A/FYTTD1/U2AF1/SRSF3/SNRPA1/RNF113A/BCAS2/RBM39/MOCS2/RAF1/FBXL4/SFPQ/BASP1/HEXIM2/PPP1R16B/THAP7/POLI/IL16/CD2BP2/SUMO1/CBLL1/STK19/OSGEP/DDX3X/PLAG1/CSNK1A1/PRPF3/GTF2H4/SAP130/SURF2/EAF1/RBM27/RSRC1/ATXN2L/KMT2E/CWC22/FTO/SNRPB2/TAB1/PRPF40B/PRPF40A/THOC2/LUC7L2/SRSF6/SREK1/SRSF7/PRKACA/DAZAP2/CCNL2/ARHGAP18/DDX46/CDYL/CDC40/PRPF8/SF3A3/CWC25/SMNDC1/CBX4/PDX1/NDUFB1/POMP/FOXO4/HBP1/HIPK1/BRD2/RING1/POLR2D/ZNF621/PIAS3/PRPF31/DYRK3/PPP1CC/PLCB1/CNOT7/U2AF1L4/STK17A/VPS72/THOC6/SART1/SRRM1/PRKAA1/ZC3H18/SRSF4/BCLAF1/ZNF106/PNISR/BMP2K/RBM25/PIN1/SYNPO2L/PRPF19/REXO4/JADE1/TERT/HDAC5/TOPORS/USP22/SAP18/TIMM50/CCNB3/LHPP/ZBTB16/IK/EFTUD2/NRIP1/INPPL1/EIF4ENIF1/LUC7L3/TARDBP/MBD4/WT1/ADAMTS4/NOC3L/SON/GLYR1/MEF2C/ATPAF2	178
CC	GO:0030992	intraciliary transport particle B	14/7377	19/19717	0.001442	0.01163	0.008319	IFT172/IFT57/IFT80/IFT46/IFT52/HSPB11/UBXN10/IFT20/KIF17/IFT22/TRAF3IP1/IFT74/TTC30B/IFT81	14
CC	GO:0005838	proteasome regulatory particle	15/7377	21/19717	0.001623	0.01295	0.009263	PSMD11/PSMC4/ADRM1/PSMD13/PSMD6/PSMC3/PSMC6/PSMC1/PSMD8/PSMC5/PSMC2/PSMD4/PSMD1/PSMD9/PSMD3	15
CC	GO:0034708	methyltransferase complex	58/7377	113/19717	0.001732	0.01368	0.009785	TRMT6/PHF19/DPY30/CBX5/EZH2/WDR5B/METTL14/TRIM37/ZNF451/PRDM10/E2F6/ZNF513/METTL3/RUVBL2/RUVBL1/RBBP7/PRDM4/SNRPB/KAT8/MGA/RBBP4/TRMT61B/SIRT1/INO80C/CBLL1/MCRS1/KDM4B/SNRPD1/HDAC2/LAS1L/DNMT3L/SNRPF/PHF20/KDM5B/WDR4/PRMT5/KDM6B/KDM4D/PRPF31/AEBP2/TEX10/WDR77/TAF4/CLNS1A/KDM5C/MEN1/KMT2B/ZNF507/EZH1/PAXIP1/PRMT1/WDR82/WDR5/SNRPG/SNRPD2/TAF7/KDM4A/ZNF335	58
CC	GO:0000152	nuclear ubiquitin ligase complex	26/7377	43/19717	0.001786	0.01382	0.00989	MAD2L2/BARD1/PHC2/UBE2S/PCGF2/PCGF1/PCGF3/CBX7/CDC23/BCOR/RNF7/ANAPC5/ANAPC7/CBX4/UBE2C/RING1/CDC26/BRCA1/PHC1/ANAPC4/CDC27/CDC20/ANAPC11/RBX1/BRCC3/ANAPC13	26
CC	GO:1902562	H4 histone acetyltransferase complex	26/7377	43/19717	0.001786	0.01382	0.00989	ZZZ3/DR1/MORF4L2/KAT2B/MRGBP/ACTB/RUVBL2/RUVBL1/EPC2/MBIP/MSL3/YEATS4/KAT8/BRD8/MCRS1/KAT5/ING3/KANSL1L/EPC1/KAT2A/MSL1/UBAP2L/POLE4/TADA3/ACTL6A/WDR5	26
CC	GO:1905354	exoribonuclease complex	17/7377	25/19717	0.001866	0.0143	0.01023	DIS3L/ZFC3H1/WDR74/LAS1L/GTPBP1/EXOSC2/EXOSC7/SUPV3L1/MPHOSPH6/DIS3L2/EXOSC9/EXOSC3/EXOSC6/PNPT1/EXOSC8/C1D/EXOSC5	17
CC	GO:0030131	clathrin adaptor complex	19/7377	29/19717	0.001977	0.015	0.01073	FCHO1/AP1B1/FCHO2/TBC1D5/AFTPH/AP3M2/AP1M2/AP1G2/AP2A2/KIAA1107/AP2S1/AP2A1/AP4B1/AP3B1/AP1G1/AP3M1/AP1M1/AP2M1/PICALM	19
CC	GO:0000177	cytoplasmic exosome (RNase complex)	11/7377	14/19717	0.002082	0.01564	0.01119	DIS3L/GTPBP1/EXOSC2/EXOSC7/SUPV3L1/EXOSC9/EXOSC3/EXOSC6/PNPT1/EXOSC8/EXOSC5	11
CC	GO:0001725	stress fiber	37/7377	67/19717	0.00224	0.01652	0.01181	SH2B2/FHOD1/PDLIM1/FBLIM1/FHL3/ACTN4/TRIP6/TPM3/LIMA1/DAAM1/PDLIM7/ACTN1/CORO1B/PTK2/MYH9/LIMCH1/ZYX/CNN2/TPM4/PDLIM5/LCP1/PGM5/ABLIM3/TPM1/MICALL2/ROR1/SIPA1L3/CYBA/PXN/FLNB/MYLK/FSCN1/PRKCZ/PDLIM4/ACTA1/SYNPO/ABLIM1	37
CC	GO:0097517	contractile actin filament bundle	37/7377	67/19717	0.00224	0.01652	0.01181	SH2B2/FHOD1/PDLIM1/FBLIM1/FHL3/ACTN4/TRIP6/TPM3/LIMA1/DAAM1/PDLIM7/ACTN1/CORO1B/PTK2/MYH9/LIMCH1/ZYX/CNN2/TPM4/PDLIM5/LCP1/PGM5/ABLIM3/TPM1/MICALL2/ROR1/SIPA1L3/CYBA/PXN/FLNB/MYLK/FSCN1/PRKCZ/PDLIM4/ACTA1/SYNPO/ABLIM1	37
CC	GO:0009898	cytoplasmic side of plasma membrane	75/7377	154/19717	0.002668	0.01948	0.01393	FYN/EZR/LYN/KCNAB2/HCK/GNAI3/GM2A/GNB1/GNA15/ESYT2/BIRC2/CD2/RGS2/GNG5/RGS1/CYTH1/PTPRC/PTP4A1/S100A6/CBX6/KRAS/GNG7/CHMP4B/EXOC1/GNAQ/PTK2B/SYAP1/PTPN7/TRAF6/HTRA2/SNX18/PTPN22/FGR/TRAF3/PTK6/PTPN4/C2CD2L/LCK/CYLD/GNG2/G6PD/RASA3/PGM5/GNAI2/KCNAB1/MAP2K2/OSBPL2/FER/FRK/CNR2/ASPSCR1/TRAF2/ATP2A2/MYZAP/STAC2/GNA13/SNX5/EPB41/SLC4A1/DTNA/GNG11/TRAF5/MATK/KCNIP1/SPTA1/MIEN1/GNG12/DIABLO/RHOA/SNX9/CHUK/SHANK3/GNA11/NTSR1/NPTXR	75
CC	GO:0005811	lipid droplet	43/7377	81/19717	0.002876	0.0208	0.01488	LPCAT2/RBP1/FABP4/TSC1/TMEM135/RAP1B/ABHD4/CKAP4/GAPDH/PLIN3/RDH10/STARD13/PLIN2/BCAP31/AIFM2/PNPLA3/DHRS3/SCCPDH/PITPNM1/TRAF6/ACSL4/FIG4/RSAD2/SYNGR2/RAB3GAP1/DFFA/EHD1/DGAT2/G0S2/CIDEC/EDA/RAB5C/PNPLA5/ATG2B/OSBPL2/CYB5R3/SET/PRPF19/VCP/ANXA2/SIGMAR1/LPCAT1/GIMAP7	43
CC	GO:0000922	spindle pole	79/7377	164/19717	0.003042	0.0218	0.0156	KLHL21/PPP2CA/NUP62/RAB11A/NEDD9/DYNC1LI1/ODF2/SPDL1/HAUS8/PSRC1/CEP104/LATS1/MAPKBP1/IKBKG/UBXN2B/PLK2/KLHL22/NPM1/CDK5RAP2/CCDC155/EMD/NSFL1C/SPAG5/CEP44/KIF2A/CTDP1/ASPM/PLK3/BCCIP/YPEL5/TMEM201/BOD1L1/RGS14/TUBGCP3/KIF20B/CKAP5/DSN1/ZW10/VPS4B/CEP63/TTC28/KATNA1/FRY/TUBGCP5/FAM161A/GPSM2/CETN1/HAUS1/KATNAL1/CEP19/DLGAP5/CEP95/SMC3/WDR60/KATNB1/TOPBP1/FAM110A/LATS2/CDC20/NUDCD2/STAG1/MISP/TOPORS/AURKA/BRCC3/AUNIP/BEX4/IK/EFHC1/CSPP1/UXT/CEP85/NEK7/POC1B/BOD1/AAAS/ALMS1/PRC1/RMDN2	79
CC	GO:0005938	cell cortex	139/7377	308/19717	0.003123	0.02217	0.01586	MYADM/CTTNBP2/EZR/PLS1/ARF6/CRIP2/GYPC/TSC1/FMNL1/CAPN2/MYO9B/NEDD9/FLNA/RHOC/MLPH/ACTN4/FLOT1/CTBP2/HFE/SPIRE1/C2CD5/TNFAIP2/AKAP13/PVALB/EXOC6B/PKD2/ACTR2/RND3/HCLS1/MPP1/ACTB/EXOC1/RDX/PFN1/UNC13B/MARCKS/PTK2B/CAPZA2/GMFG/CORO1A/TRAF6/RHOG/RYR1/CAP1/ENO1/PAFAH1B1/FCHSD1/CTSZ/EMD/SAPCD2/AGTRAP/CLTB/C2CD2L/CAPZA1/RASAL3/MAPRE1/MED28/CYTIP/SH3BP1/GPSM1/SPTBN1/FGF1/ARV1/FLOT2/RHOU/ARC/BIN2/PTK2/MYH9/TPM4/GLRX3/WIPF2/COTL1/NEDD4/WDPCP/ERMN/RHOQ/TRIP10/CFL1/ADD3/RHOV/FER/RHOF/PARD6B/HMCN1/DMTN/CORO1C/ACTR3/RHOH/PXN/LASP1/PDZD4/FLNB/NSMF/FRY/CLASP2/MYL12B/GPSM2/BIN3/TRAF2/SCIN/MYZAP/PSEN1/MKLN1/ASTN2/HAMP/TCHP/EXOC3L1/PPFIA3/EPB41/SLC4A1/MYO10/EXOC4/EPB42/RHOBTB3/SPTA1/LLGL1/TRAK1/GRK4/SPTBN2/WIPF1/EPB41L2/NRBP1/BFSP2/PRKCZ/MISP/ANXA2/CAP2/RHOA/TRPV4/SNCA/SNX9/CIB2/SHROOM1/RIMS2/WAS/LANCL2/EXOC2/KNCN	139
CC	GO:0035869	ciliary transition zone	36/7377	66/19717	0.003381	0.02379	0.01702	SPATA7/TCTN1/IFT57/KIFAP3/PCM1/CEP131/C5orf30/WDR19/IFT52/RPGRIP1/B9D1/BBS4/TCTN2/NPHP4/MAK/DYNC2LI1/MKS1/LCA5/TBCC/FAM161A/CETN1/CETN2/BBS9/TMEM231/IFT20/KIF17/TMEM80/PCDHB13/UNC119B/PCDHB15/TRAF3IP1/TOPORS/TTBK2/TMEM107/NEK4/RP1	36
CC	GO:0000178	exosome (RNase complex)	16/7377	24/19717	0.003457	0.02382	0.01704	DIS3L/ZFC3H1/WDR74/GTPBP1/EXOSC2/EXOSC7/SUPV3L1/MPHOSPH6/DIS3L2/EXOSC9/EXOSC3/EXOSC6/PNPT1/EXOSC8/C1D/EXOSC5	16
CC	GO:0044322	endoplasmic reticulum quality control compartment	16/7377	24/19717	0.003457	0.02382	0.01704	RNF103/FBXO6/RNF139/TRIM13/EDEM1/EDEM2/MAN1B1/ASGR2/CANX/DERL2/CALR/RNF185/RNF5/EDEM3/ERLEC1/OS9	16
CC	GO:0035631	CD40 receptor complex	9/7377	11/19717	0.003477	0.02382	0.01704	CD40/BIRC2/TRAF6/HTRA2/TRAF3/TRAF2/TRAF5/DIABLO/CHUK	9
CC	GO:0071007	U2-type catalytic step 2 spliceosome	19/7377	30/19717	0.00351	0.02383	0.01705	PPIL1/CRNKL1/SYF2/SNRPB/SNRPA1/BCAS2/BUD31/DHX8/SNRPD1/CWC22/SNRPB2/SNRPF/CDC40/PRPF8/PRPF19/AQR/EFTUD2/SNRPG/SNRPD2	19
CC	GO:0032432	actin filament bundle	40/7377	75/19717	0.003553	0.02392	0.01711	SH2B2/PLS1/FHOD1/PDLIM1/FBLIM1/FHL3/ACTN4/TRIP6/TPM3/LIMA1/DAAM1/MARCKS/PDLIM7/ACTN1/CORO1B/PTK2/MYH9/LIMCH1/ZYX/CNN2/TPM4/PDLIM5/LCP1/PGM5/ABLIM3/TPM1/MICALL2/PLS3/ROR1/SIPA1L3/CYBA/PXN/FLNB/MYLK/FSCN1/PRKCZ/PDLIM4/ACTA1/SYNPO/ABLIM1	40
CC	GO:0120111	neuron projection cytoplasm	44/7377	84/19717	0.003612	0.02401	0.01718	SOD1/BLOC1S2/ABHD13/ZC3H14/WLS/ABHD12/UCHL1/KIF3B/HIF1A/HSPB1/BAIAP2/AP3M2/TRAK2/PURA/PAFAH1B1/DTNBP1/BLOC1S6/KIF4A/SFPQ/LRRK2/FLOT2/ARL8A/BLOC1S3/KCNAB1/NDEL1/ADA/CANX/BLOC1S1/BLOC1S4/AP3B1/MAP1A/FMR1/MAPK1/MAP2K4/KIF17/KIF1B/AP3M1/KIF5B/TRAK1/GABARAPL1/KIF1C/MGARP/ARL8B/TRIM46	44
CC	GO:0005782	peroxisomal matrix	29/7377	51/19717	0.003661	0.02401	0.01718	FAR2/HMGCL/ACAA1/PHYH/SCP2/ABCD3/ECH1/CAT/AGPS/ACOX1/ECI2/HSD17B4/IDH1/ACOX2/DAO/MLYCD/NUDT19/TYSND1/EHHADH/FAR1/NUDT7/ACOX3/GNPAT/CROT/GRHPR/HACL1/HAO1/ACOT8/PIPOX	29
CC	GO:0031907	microbody lumen	29/7377	51/19717	0.003661	0.02401	0.01718	FAR2/HMGCL/ACAA1/PHYH/SCP2/ABCD3/ECH1/CAT/AGPS/ACOX1/ECI2/HSD17B4/IDH1/ACOX2/DAO/MLYCD/NUDT19/TYSND1/EHHADH/FAR1/NUDT7/ACOX3/GNPAT/CROT/GRHPR/HACL1/HAO1/ACOT8/PIPOX	29
CC	GO:0070821	tertiary granule membrane	39/7377	73/19717	0.003812	0.0248	0.01774	ITGAM/FPR2/CLEC5A/LILRB2/LILRA3/GPR84/SLC11A1/OLR1/CLEC4D/KCNAB2/MCEMP1/MGAM/CD93/SLC2A3/ADAM8/CD59/ATP6V0C/CLEC12A/PLD1/FCAR/CD53/PTAFR/RAP2C/NBEAL2/RAP2B/LAIR1/ATP6AP2/TRPM2/TMEM63A/CD47/NRAS/CD300A/CYBA/CYBB/GAA/VAMP1/SERPINB6/CD33/CEACAM8	39
CC	GO:0098687	chromosomal region	155/7377	349/19717	0.004062	0.0262	0.01874	SUN2/PPP2CA/EID3/NUP160/ZNF330/MCM6/DYNC1LI1/MCM2/CEBPB/CBX5/NABP1/EZH2/HAT1/SPDL1/ERCC4/ALYREF/DOT1L/KAT2B/SUV39H2/REC8/SYCP3/CENPW/SMC5/SIN3A/NUP85/SMC6/SEH1L/CLIP1/ORC5/ZNF276/RPA1/PDS5A/CENPE/CBX1/DDB1/NUP43/SP100/HNRNPA2B1/PURA/PAFAH1B1/CCDC155/SIRT7/WRNIP1/TEP1/DSCC1/NSMCE2/XRCC5/KAT8/CENPT/PML/CENPN/SMCHD1/SKA2/SPAG5/MIS12/PPP2R5C/NAT10/ZNF207/CENPC/MBD5/PSEN2/PTGES3/ATM/CSNK1A1/SETX/CHAMP1/ZNFX1/NCAPD3/BUB3/IKZF1/SUV39H1/NHP2/RAD17/NDC80/PCNA/XRCC1/BOD1L1/CBX3/ERCC1/ZWILCH/THOC2/GAR1/CTCF/CKAP5/DCTN2/NUP107/DSN1/NDEL1/PHF6/NUF2/TOX4/INCENP/ZW10/ORC4/LIG4/ERCC6L/CENPK/THOC5/KDM4D/DCLRE1A/DYNLT3/PPP1CC/PMF1/PPP1CA/CLASP2/STAG3/ATR/RCC2/SS18L1/DNMT3A/THOC6/SSB/PSEN1/FMR1/MCM5/RTEL1/TELO2/ACD/KIF2C/CTC1/POLD1/SMC3/SPC25/SCMH1/XRCC6/DCLRE1C/MTBP/SNAI1/CENPA/PPP1CB/PKHD1/NUDCD2/MEN1/NLRP2/STAG1/ORC3/DYNC1LI2/TERT/FBXO28/CENPL/AURKA/CDC73/POT1/CENPI/DCTN6/EZH1/WDR82/MIS18BP1/DCTN5/DAXX/FEN1/RECQL4/BOD1/SKA3/UPF1	155
CC	GO:0030119	AP-type membrane coat adaptor complex	26/7377	45/19717	0.004329	0.02745	0.01964	FCHO1/AP1B1/FCHO2/TBC1D5/VPS41/AP5B1/AFTPH/AP3M2/VPS33A/AP5S1/AP1M2/AP1G2/AP2A2/VPS18/AP4S1/KIAA1107/AP2S1/AP2A1/AP4B1/AP3B1/AP1G1/AP5M1/AP3M1/AP1M1/AP2M1/PICALM	26
CC	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	62/7377	126/19717	0.00443	0.02745	0.01964	SERPINA1/FN1/F5/STK17B/CD55/ATP6AP1/MCFD2/PTPN2/LMAN2L/CHP1/TAP2/TAP1/CTSC/SEC22B/BCAP31/CD59/MGAT4B/NUCB2/CLN8/GOLGB1/CSNK1D/LRPAP1/CNIH3/TRAPPC5/HSPA5/ERGIC1/CTSZ/TMED10/ERP44/HMGB1/BET1/GOSR2/PRRG4/GNPNAT1/CNIH4/TAPBP/STX5/DICER1/RGMB/PDIA6/TBC1D20/MPPE1/COPG2/MTMR6/COL7A1/IST1/LMAN1/YKT6/CALR/TMED5/SEC23IP/ASPSCR1/VMA21/DCSTAMP/TMED4/COPZ2/YIF1B/YIF1A/AZIN2/RER1/ERGIC2/TM6SF2	62
CC	GO:0001931	uropod	10/7377	13/19717	0.004436	0.02745	0.01964	ICAM2/EZR/BST1/FLOT1/PSTPIP1/FLOT2/MYH9/SELPLG/MSN/PIP5K1B	10
CC	GO:0031254	cell trailing edge	10/7377	13/19717	0.004436	0.02745	0.01964	ICAM2/EZR/BST1/FLOT1/PSTPIP1/FLOT2/MYH9/SELPLG/MSN/PIP5K1B	10
CC	GO:0044233	Mitochondria-associated ER Membrane	10/7377	13/19717	0.004436	0.02745	0.01964	MBOAT7/ATG14/ACSL4/PDZD8/RAB32/RAB38/ZFYVE1/CANX/TOMM20/SERAC1	10
CC	GO:0071013	catalytic step 2 spliceosome	45/7377	87/19717	0.004469	0.02745	0.01964	HNRNPR/HNRNPH1/ALYREF/PPIL1/MAGOHB/CRNKL1/WDR83/HNRNPK/SYF2/SNRNP200/HNRNPA1/CACTIN/HNRNPA2B1/RBM8A/SNRPB/U2AF1/SNRPA1/BCAS2/BUD31/DHX8/LSM7/SNRPD1/ZCCHC8/ISY1/CWC22/SNRPB2/HNRNPC/SNRPF/RALY/CDC40/PRPF8/SF3A3/HNRNPM/SART1/SRRM1/DHX38/HNRNPA3/PRPF19/SNRPN/AQR/PPWD1/EFTUD2/SYNCRIP/SNRPG/SNRPD2	45
CC	GO:1904949	ATPase complex	51/7377	101/19717	0.004878	0.02973	0.02127	BAZ1A/ATP1A1/CHRAC1/ABCD4/SLC9A1/ANP32E/BPTF/ZBTB7A/MTA3/RUVBL2/RUVBL1/ABCB6/MBD3/RBBP7/RBBP4/ARID1B/ATP1B2/UCHL5/SMARCA1/BRD8/INO80C/TFPT/MCRS1/ATP1B3/ACTR5/HDAC2/KAT5/FXYD1/ATP1B1/YY1/DPF2/RSF1/PBRM1/BRD9/ING3/SS18L1/PHF10/SS18/ATP1B4/SMARCC2/FXYD2/RB1/SMARCA5/VCP/NCR1/SMARCC1/ATP1A2/MTA2/ATAD5/ACTL6A/ATP12A	51
CC	GO:0031902	late endosome membrane	65/7377	134/19717	0.005518	0.03337	0.02387	CYB561A3/SLC29A3/SLC11A1/SLC9A9/MCOLN1/WDR91/MMD/ABHD6/OSBPL9/WDR81/LAMP2/LAMP3/LAMP1/VPS37B/IFITM3/PLD1/VPS41/CHMP4B/MICALL1/CD63/SPPL2A/RNF13/FIG4/CLCN3/LAMTOR1/VPS33A/VPS37C/TMEM9/STARD3NL/HLA-DMB/TMEM106B/ABCA5/GOSR2/AP5S1/HLA-DRA/HLA-DMA/ATG9A/ARL8A/LAMTOR4/ANXA6/VPS18/CHMP2A/TSG101/HGS/VTI1A/VPS4B/RAB7B/MCOLN2/LAMTOR5/LAPTM4B/LTV1/CLCN4/AP5M1/VTI1B/STX8/VPS16/MREG/ANXA2/VAC14/CHMP1B/MCOLN3/SNX16/RAB27A/SLC38A9/ARL8B	65
CC	GO:0071005	U2-type precatalytic spliceosome	28/7377	50/19717	0.005698	0.03419	0.02446	PRPF4/PRPF38A/MAGOHB/LSM5/SNRNP200/SNRPB/TXNL4A/SNRPA1/RNF113A/LSM7/SNIP1/SNRPD1/PRPF3/MFAP1/CWC22/SNRPB2/SNRPF/PRPF8/SF3A3/SF3B4/PRPF31/RBMX2/SART1/IK/DHX16/EFTUD2/SNRPG/SNRPD2	28
CC	GO:0042641	actomyosin	41/7377	79/19717	0.005998	0.03571	0.02555	SH2B2/FHOD1/PDLIM1/FBLIM1/FHL3/ACTN4/TRIP6/TPM3/KAT2B/LIMA1/DAAM1/MYO5A/PDLIM7/ACTN1/ACTC1/CORO1B/PTK2/MYH9/LIMCH1/ZYX/CNN2/TPM4/PDLIM5/LCP1/PGM5/ABLIM3/TPM1/HDAC4/MICALL2/ROR1/SIPA1L3/CYBA/PXN/FLNB/MYLK/FSCN1/PRKCZ/PDLIM4/ACTA1/SYNPO/ABLIM1	41
CC	GO:0030990	intraciliary transport particle	17/7377	27/19717	0.006208	0.03668	0.02624	IFT172/IFT57/IFT80/WDR19/IFT46/IFT52/HSPB11/UBXN10/DYNC2LI1/IFT20/KIF17/IFT22/WDR35/TRAF3IP1/IFT74/TTC30B/IFT81	17
CC	GO:0035097	histone methyltransferase complex	44/7377	86/19717	0.006327	0.0371	0.02654	PHF19/DPY30/CBX5/EZH2/WDR5B/TRIM37/ZNF451/PRDM10/E2F6/ZNF513/RUVBL2/RUVBL1/RBBP7/PRDM4/KAT8/MGA/RBBP4/SIRT1/INO80C/MCRS1/KDM4B/HDAC2/LAS1L/DNMT3L/PHF20/KDM5B/PRMT5/KDM6B/KDM4D/PRPF31/AEBP2/TEX10/TAF4/KDM5C/MEN1/KMT2B/ZNF507/EZH1/PAXIP1/WDR82/WDR5/TAF7/KDM4A/ZNF335	44
CC	GO:0030118	clathrin coat	26/7377	46/19717	0.00645	0.03753	0.02685	FCHO1/AP1B1/FCHO2/TBC1D5/VPS41/AFTPH/SYNJ1/AP3M2/IGF2R/CLTB/VPS33A/AP1M2/AP1G2/CLTCL1/AP2A2/KIAA1107/AP2S1/NECAP2/AP2A1/AP4B1/AP3B1/AP1G1/AP3M1/AP1M1/AP2M1/PICALM	26
CC	GO:0030134	COPII-coated ER to Golgi transport vesicle	47/7377	93/19717	0.006571	0.03795	0.02715	SERPINA1/F5/MCFD2/LMAN2L/KLHL12/CTSC/SEC22B/CD59/CD74/SAR1B/HLA-F/CNIH3/HLA-DPB1/HLA-DPA1/HLA-E/HLA-B/CTSZ/TMED10/HLA-G/GOSR2/HLA-DRA/TEX261/IER3IP1/STX5/HLA-C/SAR1A/SCAP/COL7A1/LMAN1/VTI1A/PEF1/SREBF2/TMED5/SEC23IP/VMA21/TMED4/HLA-DQB2/VTI1B/YIPF6/HLA-A/YIF1B/YIF1A/APP/ERGIC2/SEC24A/SEC31B/SEC16B	47
CC	GO:0098562	cytoplasmic side of membrane	83/7377	178/19717	0.007178	0.04115	0.02944	FYN/EZR/LYN/KCNAB2/HCK/GNAI3/GM2A/GNB1/GNA15/ESYT2/BIRC2/CD2/RGS2/GNG5/RGS1/CYTH1/PTPRC/PTP4A1/S100A6/CBX6/PKD2/KRAS/GNG7/CHMP4B/EXOC1/GNAQ/PTK2B/SYAP1/PTPN7/TRAF6/SPPL2A/HTRA2/SNX18/PTPN22/FGR/TRAF3/PTK6/PTPN4/C2CD2L/RASAL3/LCK/CYLD/LRRK2/GNG2/G6PD/RASA3/PGM5/GNAI2/RAB5A/KCNAB1/MAP2K2/OSBPL2/CISD1/FER/FRK/CNR2/EEF1A2/ASPSCR1/TRAF2/ATP2A2/MYZAP/STAC2/GNA13/SNX5/EPB41/SLC4A1/DTNA/GNG11/TRAF5/MATK/KCNIP1/SPTA1/DNAJA1/MIEN1/GNG12/DIABLO/RHOA/SNX9/CHUK/SHANK3/GNA11/NTSR1/NPTXR	83
CC	GO:0070382	exocytic vesicle	95/7377	207/19717	0.007386	0.04204	0.03007	IGF1/SLC40A1/CTTNBP2/APBA1/DPYSL3/STX7/STX11/SYT11/SYTL1/SEC22B/STXBP5/LAMP1/WDR7/SLC2A8/SYPL1/UNC13B/SGTA/WFS1/RABAC1/TPRG1L/VAMP3/PDE4B/CLCN3/SCAMP1/SYNGR2/TMEM230/C16orf70/CLTB/DTNBP1/CLN3/SEMA4C/RAB8A/LRRK2/SYT6/PSEN2/ATG9A/ROGDI/TOR1A/DNM1/DISC1/UNC13D/RAB5A/KIAA1107/NDEL1/SYTL4/STX16/MTMR2/VDAC2/NKD2/VTI1A/PTPRN2/SLC17A5/DNM1L/VDAC1/RAB8B/ICA1/SYT13/PSEN1/SYNGR3/SYNGR4/RAB3A/RAB35/STX12/SYPL2/VTI1B/SYT9/SYTL2/ZNRF1/SYT1/OPRD1/RAB3B/SYT2/VAMP1/DOC2A/SYT4/SNCAIP/SYT5/SCAMP5/PICK1/BRSK1/APP/RAB3D/SNCA/SLC9B2/ATP6V1B1/APH1A/PICALM/SYN3/RAB27A/RAB26/BIN1/AMPH/DMXL2/LGI3/SV2B	95
CC	GO:0030117	membrane coat	48/7377	96/19717	0.00783	0.04391	0.03141	FCHO1/KLHL12/AP1B1/FCHO2/TBC1D5/VPS41/CHMP4B/AP5B1/AFTPH/SAR1B/SYNJ1/COPE/AP3M2/IGF2R/ARFGAP3/CLTB/VPS33A/AP5S1/AP1M2/AP1G2/CLTCL1/SAR1A/DNM1/AP2A2/VPS18/COPG2/CHMP2A/AP4S1/COPA/KIAA1107/AP2S1/NECAP2/PEF1/AP2A1/AP4B1/ARCN1/AP1S3/AP3B1/AP1G1/AP5M1/AP3M1/AP1M1/COPZ2/AP2M1/CHMP1B/PICALM/SEC24A/SEC31B	48
CC	GO:0048475	coated membrane	48/7377	96/19717	0.00783	0.04391	0.03141	FCHO1/KLHL12/AP1B1/FCHO2/TBC1D5/VPS41/CHMP4B/AP5B1/AFTPH/SAR1B/SYNJ1/COPE/AP3M2/IGF2R/ARFGAP3/CLTB/VPS33A/AP5S1/AP1M2/AP1G2/CLTCL1/SAR1A/DNM1/AP2A2/VPS18/COPG2/CHMP2A/AP4S1/COPA/KIAA1107/AP2S1/NECAP2/PEF1/AP2A1/AP4B1/ARCN1/AP1S3/AP3B1/AP1G1/AP5M1/AP3M1/AP1M1/COPZ2/AP2M1/CHMP1B/PICALM/SEC24A/SEC31B	48
CC	GO:0071011	precatalytic spliceosome	28/7377	51/19717	0.008179	0.04554	0.03258	PRPF4/PRPF38A/MAGOHB/LSM5/SNRNP200/SNRPB/TXNL4A/SNRPA1/RNF113A/LSM7/SNIP1/SNRPD1/PRPF3/MFAP1/CWC22/SNRPB2/SNRPF/PRPF8/SF3A3/SF3B4/PRPF31/RBMX2/SART1/IK/DHX16/EFTUD2/SNRPG/SNRPD2	28
CC	GO:0001772	immunological synapse	21/7377	36/19717	0.008592	0.04725	0.0338	EZR/STX7/BCL10/ALCAM/DUSP3/CD53/CORO1A/SOCS6/GZMA/NPTN/LCK/SNX27/MYH9/GZMB/RHOH/HAVCR2/SKAP1/PRKCQ/CD3E/LAT/PTPRJ	21
CC	GO:0030665	clathrin-coated vesicle membrane	56/7377	115/19717	0.008618	0.04725	0.0338	NRGN/FCGR1B/FCGR1A/WNT5A/FCHO1/AP1B1/FCHO2/DENND1A/CD74/APOE/TBC1D5/M6PR/IL7R/SLC2A8/AFTPH/ROR2/HLA-DPB1/HLA-DPA1/VAMP3/IGF2R/CLTB/CD3D/LDLR/HLA-DRA/AP1M2/AP1G2/CLTCL1/AP2A2/RAB5A/KIAA1107/ADRB2/AP2S1/CD3G/NECAP2/FZD5/CHRM2/AP2A1/CEMIP/EGFR/AP3B1/FZD4/TFRC/AP1G1/RAB3A/HLA-DQB2/RAB35/SYT9/AP1M1/SYT1/HBEGF/CD4/SYT2/AP2M1/FZD2/PICALM/AVPR2	56
CC	GO:0030658	transport vesicle membrane	95/7377	208/19717	0.008669	0.04725	0.0338	NRGN/SYT11/MCFD2/KLHL12/SEC22B/LAMP1/CD59/CD74/SYPL1/ITPR1/UNC13B/AFTPH/SGTA/SAR1B/WFS1/HLA-F/CNIH3/TPRG1L/HLA-DPB1/HLA-DPA1/HLA-E/HLA-B/VAMP3/CLCN3/SCAMP1/SYNGR2/C16orf70/TMED10/CLTB/DTNBP1/SEMA4C/HLA-G/GOSR2/HLA-DRA/LRRK2/AP1G2/SYT6/CLTCL1/STX5/HLA-C/SAR1A/SCG3/PAM/RPH3AL/SCAP/RAB5A/SYTL4/STX16/LMAN1/VTI1A/PEF1/PTPRN2/SREBF2/SLC17A5/DNM1L/AP2A1/SEC23IP/ICA1/AP1G1/VMA21/SYNGR3/SYNGR4/RAB3A/HLA-DQB2/RAB35/STX12/SYPL2/VTI1B/SYT9/SNTB2/HLA-A/ZNRF1/SYT1/TMEM30A/OPRD1/RAB3B/DBH/SYT2/VAMP1/DOC2A/SYT4/SYT5/SCAMP5/SNCA/SLC9B2/ATP6V1B1/SYCN/SEC24A/SYN3/RAB26/AMPH/SEC31B/SEC16B/DMXL2/SV2B	95
CC	GO:0000118	histone deacetylase complex	31/7377	58/19717	0.009247	0.04952	0.03543	ZNF217/CBX5/ZBTB7A/SIN3A/MTA3/MBD3/RBBP7/HINT1/SATB2/HDAC11/RBBP4/ELMSAN1/SIN3B/SUDS3/TAL1/BRMS1L/SAP130/HDAC10/HDAC2/NCOR1/HDAC7/HDAC4/TAF6L/HEY2/PHF21A/TBL1X/HDAC5/SAP18/MTA2/NRIP1/BRMS1	31
CC	GO:0008540	proteasome regulatory particle, base subcomplex	9/7377	12/19717	0.009278	0.04952	0.03543	PSMC4/PSMC3/PSMC6/PSMC1/PSMC5/PSMC2/PSMD4/PSMD1/PSMD9	9
CC	GO:0034709	methylosome	9/7377	12/19717	0.009278	0.04952	0.03543	SNRPB/SNRPD1/SNRPF/PRMT5/WDR77/CLNS1A/PRMT1/SNRPG/SNRPD2	9
CC	GO:0002102	podosome	18/7377	30/19717	0.009931	0.05232	0.03742	LPXN/VCL/ADAM8/SH3PXD2A/ACTR2/KIF9/HNRNPK/SVIL/ARHGEF2/RHOU/BIN2/TPM4/SH3GL1/LCP1/AFAP1L1/SCIN/FSCN1/ASAP1	18
CC	GO:0008287	protein serine/threonine phosphatase complex	25/7377	45/19717	0.01	0.05232	0.03742	IER5/PPP2CA/PPP1R15A/SHOC2/PPP4C/PPP4R2/PPP3CB/ITPR1/PPP2R3A/NCK1/PPP1R15B/PPP2R5C/PPP2R2D/PPP2R2B/PPP1R3B/TOX4/PPP4R1/PPP1CC/PPP1CA/PPP2R1B/PPP1R11/PPP1CB/PPP2R5B/WDR82/PPP2R2C	25
CC	GO:1903293	phosphatase complex	25/7377	45/19717	0.01	0.05232	0.03742	IER5/PPP2CA/PPP1R15A/SHOC2/PPP4C/PPP4R2/PPP3CB/ITPR1/PPP2R3A/NCK1/PPP1R15B/PPP2R5C/PPP2R2D/PPP2R2B/PPP1R3B/TOX4/PPP4R1/PPP1CC/PPP1CA/PPP2R1B/PPP1R11/PPP1CB/PPP2R5B/WDR82/PPP2R2C	25
CC	GO:0090543	Flemming body	17/7377	28/19717	0.01034	0.05373	0.03843	USP3/ARF6/NUP62/CNTRL/EXOC1/CAPG/CENPC/CHAMP1/CEP55/TSG101/NTNG2/IST1/VPS4B/EXOC4/ZFYVE19/KIF14/EXOC2	17
CC	GO:0030863	cortical cytoskeleton	56/7377	116/19717	0.01068	0.05467	0.03911	MYADM/EZR/PLS1/GYPC/CAPN2/FLNA/MLPH/ACTN4/FLOT1/HFE/AKAP13/PVALB/ACTR2/HCLS1/MPP1/ACTB/RDX/CAPZA2/GMFG/CORO1A/CAP1/FCHSD1/CAPZA1/MAPRE1/MED28/SPTBN1/FLOT2/MYH9/TPM4/WIPF2/COTL1/CFL1/DMTN/ACTR3/LASP1/NSMF/BIN3/MYZAP/EPB41/SLC4A1/EPB42/SPTA1/LLGL1/SPTBN2/WIPF1/EPB41L2/MISP/CAP2/TRPV4/SNX9/CIB2/SHROOM1/RIMS2/WAS/LANCL2/KNCN	56
CC	GO:0019898	extrinsic component of membrane	130/7377	295/19717	0.01071	0.05467	0.03911	S100A10/FYN/EZR/ANXA1/BST1/SOCS3/LYN/AZU1/KCNAB2/NMT2/HCK/FCN1/GNAI3/WDR91/GNB1/SMAD7/GNA15/SYTL1/PACSIN2/SNX10/ESYT2/ATG14/WDR81/GNG5/RGS1/STXBP5/CYTH1/DEFB1/MGLL/CISH/S100A6/KRAS/VPS13A/PIK3R3/GNG7/SGTA/GRIPAP1/COQ7/CTNNA1/GNAQ/COQ5/SOCS5/PTK2B/SYAP1/MICALL1/NCF1/SNX18/SOCS6/FGR/NUMB/PTK6/PIK3R6/PML/BLOC1S6/ATG13/WIPI1/COQ3/SOCS7/LCK/SNX33/CDH5/CYLD/PLAUR/GNG2/SYT6/TOR1A/ALOX15B/BCL2L11/ZFYVE1/VPS13D/GFRA2/GNAI2/GFRA3/PIK3CD/JAKMIP1/KCNAB1/SYTL4/ATG2B/WDR45B/OSBPL2/COQ6/NOA1/FER/FRK/CNR2/AP4B1/DMBT1/ULK1/GML/ASPSCR1/ATP2A2/MYZAP/CDH17/STAC2/FMR1/GNA13/MTMR3/SNX5/CNTFR/SOCS1/DTNA/SYTL2/GNG11/CDH10/MATK/KCNIP1/GNG12/PIK3CG/RGS6/SLA2/DOC2A/ANXA2/RHOA/CDH3/MMP27/VAC14/CDHR3/SNX9/ATP6V1B1/COQ4/NRBF2/GOLGA3/CNKSR2/SNX16/PICALM/SOCS2/SHANK3/CDH26/GNA11/PIK3CB	130
CC	GO:0045334	clathrin-coated endocytic vesicle	33/7377	63/19717	0.01085	0.05467	0.03911	FCGR1B/FCGR1A/WNT5A/FCHO1/FCHO2/DVL2/CD74/APOE/TBC1D5/ROR2/HLA-DPB1/HLA-DPA1/CLTB/LDLR/HLA-DRA/CTLA4/CLTCL1/AP2A2/DNM2/KIAA1107/AP2S1/INPP5F/FZD5/AP2A1/LMBRD1/CEMIP/FZD4/HLA-DQB2/RAB35/HBEGF/AP2M1/FZD2/PICALM	33
CC	GO:0071004	U2-type prespliceosome	11/7377	16/19717	0.01095	0.05467	0.03911	SNRPB/LUC7L/LSM7/SNRPC/PRPF40B/PRPF40A/LUC7L2/PRPF39/SNRPN/LUC7L3/SNRPG	11
CC	GO:0071010	prespliceosome	11/7377	16/19717	0.01095	0.05467	0.03911	SNRPB/LUC7L/LSM7/SNRPC/PRPF40B/PRPF40A/LUC7L2/PRPF39/SNRPN/LUC7L3/SNRPG	11
CC	GO:0071437	invadopodium	11/7377	16/19717	0.01095	0.05467	0.03911	EZR/ACTR2/DPP4/PAK1/SVIL/PLAUR/AFAP1L1/ITGA3/FSCN1/MSN/RUFY3	11
CC	GO:0031307	integral component of mitochondrial outer membrane	13/7377	20/19717	0.01134	0.0552	0.03949	PINK1/GDAP1/FIS1/ABCB6/RHOT2/ARMCX3/TOMM40/CPT1A/TOMM20/MUL1/BAK1/MGARP/FUNDC1	13
CC	GO:0035267	NuA4 histone acetyltransferase complex	13/7377	20/19717	0.01134	0.0552	0.03949	MORF4L2/MRGBP/ACTB/RUVBL2/RUVBL1/EPC2/MSL3/YEATS4/BRD8/KAT5/ING3/EPC1/ACTL6A	13
CC	GO:0036019	endolysosome	13/7377	20/19717	0.01134	0.0552	0.03949	CTSS/LGMN/CTSK/LDLR/CTSB/AP2A2/AP2S1/AP2A1/TLR8/HRG/CLEC16A/TLR3/AP2M1	13
CC	GO:0043189	H4/H2A histone acetyltransferase complex	13/7377	20/19717	0.01134	0.0552	0.03949	MORF4L2/MRGBP/ACTB/RUVBL2/RUVBL1/EPC2/MSL3/YEATS4/BRD8/KAT5/ING3/EPC1/ACTL6A	13
CC	GO:0036064	ciliary basal body	63/7377	133/19717	0.01173	0.05676	0.0406	ARMC9/SPATA7/EZR/RILPL1/BBS5/TTC8/FOPNL/EVC/IFT172/PKD2/IFT57/DAAM1/KIFAP3/PCM1/WDR11/CEP131/CBY1/RP2/INTU/BBS2/RAB8A/MKKS/IFT46/CCDC88A/RPGR/CYLD/IFT52/B9D1/BBS4/CSNK1A1/NPHP4/DISC1/MLF1/DYNC2LI1/BBS7/TBC1D7/MKS1/CCDC151/LCA5/FAM161A/CETN2/CEP19/IFT20/KIF17/PKHD1/WDR35/JADE1/TRAF3IP1/DZIP1L/TOPORS/TTBK2/CEP78/NEK4/CCDC66/TTLL6/TTC30B/IFT81/POC1B/C2CD3/GAS8/WRAP73/RAB28/KNCN	63
CC	GO:0005876	spindle microtubule	31/7377	59/19717	0.0126	0.06059	0.04334	KLHL21/RAB11A/PSRC1/KIF3B/NEIL2/KIFAP3/CSNK1D/CENPE/KLHL22/PAFAH1B1/KIF4A/MAPRE1/SKA2/KIF2A/HAUS2/BOD1L1/TUBGCP3/NUSAP1/ZW10/DYNLT3/TUBG2/CLASP2/FAM161A/CAPN6/CDC27/POLB/MISP/AURKA/BOD1/PRC1/SKA3	31
CC	GO:0005788	endoplasmic reticulum lumen	135/7377	309/19717	0.01315	0.06283	0.04494	SERPINA1/FN1/F5/ADAMTSL4/COL23A1/VCAN/WNT5A/ERP29/PTGS2/CKAP4/SPP1/GOLM1/CTSC/LAMB2/TXNDC16/SUMF1/SHISA5/FKBP14/ERP27/TMEM43/PDIA3/IGFBP7/APOE/CST3/SUMF2/GPX7/ARSB/CRTAP/ESD/WFS1/COL8A2/IGFBP4/LRPAP1/COL4A2/CFP/POGLUT1/FLT3/PDGFC/QSOX1/HSPA5/RCN1/CTSZ/FOXRED2/SLC27A2/ERP44/CES2/CLU/ARSK/TOR1B/SDF2L1/IL6/EDEM2/PDGFB/PLAUR/APOL1/APOA5/SCG3/TOR1A/PDIA6/TXNDC12/SPARCL1/BMP4/COL7A1/TIMP1/ALG12/TSPAN33/LGALS1/GANAB/DNAJC10/CLN6/KTN1/RDH5/PDGFA/EBI3/PTPRN2/ANO8/DNAJB9/CANX/TSPAN5/CALR/CERCAM/STS/COL20A1/COL2A1/HSP90B1/ARSA/MXRA8/DBI/CES3/WNT1/ARSI/APOA1/MINPP1/COL4A3/CASQ1/ERAP1/COL15A1/FUCA2/CASQ2/EVA1A/HRC/AMBN/HYOU1/COL6A3/CD4/ERAP2/RCN2/MEN1/TOR4A/IL12B/COL18A1/COL11A2/MANF/APP/WNT6/DAG1/CALU/CYP2W1/MBTPS1/GCG/MSLN/EDEM3/WNT7A/PPIB/FGF23/P4HA1/CHGB/IL23A/F9/TOR3A/ERLEC1/OS9/PDGFD/GHRL/ALB	135
CC	GO:0018995	host	37/7377	73/19717	0.01399	0.06562	0.04694	GBP2/NUP62/NMT2/NUP160/NUP214/VPS37B/RAN/AXL/NUP85/SEH1L/GBP4/NUP43/CD209/VPS37C/POM121/RAB29/BICD1/NUP88/TSG101/PI4K2A/TOP2B/NUP107/UBAP1/UBC/LMAN1/IFIT1/CNOT7/NUP93/NUP205/FMR1/KPNA1/NUP50/GBP6/KPNB1/POM121C/AAAS/TOP2A	37
CC	GO:0032592	integral component of mitochondrial membrane	37/7377	73/19717	0.01399	0.06562	0.04694	SCO2/PINK1/CHCHD6/TIMM23B/SLC25A19/COX11/GDAP1/FIS1/TMEM70/APOO/MCU/ABCB6/TIMM17A/RHOT2/ETFDH/MPC2/CHCHD10/ABCB10/AFG3L2/ARMCX3/COX16/OXA1L/SFXN1/TOMM40/CPT1A/MICU1/PET100/TOMM20/COA3/MUL1/AGK/L2HGDH/BAK1/APOOL/MGARP/FUNDC1/TMEM177	37
CC	GO:0043657	host cell	37/7377	73/19717	0.01399	0.06562	0.04694	GBP2/NUP62/NMT2/NUP160/NUP214/VPS37B/RAN/AXL/NUP85/SEH1L/GBP4/NUP43/CD209/VPS37C/POM121/RAB29/BICD1/NUP88/TSG101/PI4K2A/TOP2B/NUP107/UBAP1/UBC/LMAN1/IFIT1/CNOT7/NUP93/NUP205/FMR1/KPNA1/NUP50/GBP6/KPNB1/POM121C/AAAS/TOP2A	37
CC	GO:0019005	SCF ubiquitin ligase complex	33/7377	64/19717	0.01449	0.06754	0.04832	CUL1/FBXO6/FBXW7/SKP2/FBXL5/FBXO45/FBXL20/FBXO38/FBXL18/FBXL4/FBXL3/RNF7/TRIM21/SPSB1/CACYBP/FBXO4/SPSB2/FBXL6/FBXL2/CUL2/FBXL7/FBXO27/FBXO44/CUL4B/LRRC29/FBXO25/FBXL17/FBXL14/FBXL19/RBX1/FBXL12/FBXL16/CCNF	33
CC	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane	36/7377	71/19717	0.0151	0.07	0.05007	SERPINA1/F5/CD55/ATP6AP1/MCFD2/TAP2/TAP1/CTSC/SEC22B/BCAP31/CD59/CLN8/CSNK1D/CNIH3/ERGIC1/CTSZ/TMED10/BET1/GOSR2/PRRG4/TAPBP/STX5/TBC1D20/MPPE1/COL7A1/LMAN1/YKT6/CALR/TMED5/ASPSCR1/VMA21/DCSTAMP/COPZ2/AZIN2/ERGIC2/TM6SF2	36
CC	GO:0030669	clathrin-coated endocytic vesicle membrane	24/7377	44/19717	0.01529	0.07042	0.05038	FCGR1B/FCGR1A/WNT5A/FCHO1/FCHO2/CD74/APOE/TBC1D5/ROR2/HLA-DPB1/HLA-DPA1/LDLR/HLA-DRA/AP2A2/KIAA1107/AP2S1/FZD5/AP2A1/FZD4/HLA-DQB2/HBEGF/AP2M1/FZD2/PICALM	24
CC	GO:1902555	endoribonuclease complex	18/7377	31/19717	0.0155	0.07098	0.05078	ZFP36/AGO2/RPP38/DHX9/RPP25/RPP14/CLP1/DICER1/LAS1L/TARBP2/HSD17B10/AGO1/RPP40/RPPH1/POP7/DROSHA/ERN1/TRMT10C	18
CC	GO:0012507	ER to Golgi transport vesicle membrane	32/7377	62/19717	0.01564	0.07119	0.05092	MCFD2/KLHL12/SEC22B/CD59/CD74/SAR1B/HLA-F/CNIH3/HLA-DPB1/HLA-DPA1/HLA-E/HLA-B/TMED10/HLA-G/GOSR2/HLA-DRA/STX5/HLA-C/SAR1A/SCAP/LMAN1/VTI1A/PEF1/SREBF2/SEC23IP/VMA21/HLA-DQB2/VTI1B/HLA-A/SEC24A/SEC31B/SEC16B	32
CC	GO:0036464	cytoplasmic ribonucleoprotein granule	95/7377	212/19717	0.01584	0.07171	0.0513	NFKBIZ/USP3/TUBA1A/ZFP36/C9orf72/BARD1/CKAP4/CHTOP/SQSTM1/G3BP2/AGO2/MOV10/TDRD6/GIGYF2/ACTB/PCBP1/SARNP/PSMA4/PITPNM1/STAU1/HNRNPK/MBNL1/GABPB1/RBM4/SAMD4B/PIWIL4/HABP4/TAF5L/LARP4/DDX19B/DHX9/DCP1B/DCP2/ZC3H12D/ICOSLG/NSUN2/BLNK/MOV10L1/RAC1/APOBEC3G/EIF2S1/CAPRIN1/CDK9/POLI/APOBEC3C/MAP1LC3C/TSTD1/ATXN2/LSM14A/PUM2/DDX3X/BTBD1/DCPS/PSMC3/ATXN2L/SHB/TRIM21/XRN1/HELZ/CPEB1/EDC4/AGO1/DDX1/TDRD7/TNRC6B/GRB7/TNRC6A/LIG4/POLR2D/DYRK3/LARP4B/CNOT7/CLOCK/FMR1/SOCS1/DIS3L2/EIF4E/PSMA2/EID1/ARNTL/INA/CTSG/PSMC2/SNCAIP/VCP/SAMD4A/TOP1/KPNB1/GHR/ROCK2/EIF4ENIF1/PABPC4L/TARDBP/SNRPG/UPF1	95
CC	GO:0005798	Golgi-associated vesicle	81/7377	178/19717	0.01602	0.0721	0.05158	NRGN/SERPINA1/F5/MCFD2/LMAN2L/KLHL12/CTSC/SEC22B/CD59/CD74/VPS41/ITM2B/AFTPH/SAR1B/HLA-F/SPPL2A/CNIH3/COPE/HLA-DPB1/HLA-DPA1/GOPC/HLA-E/HLA-B/IGF2R/CTSZ/ARFGAP3/TMED10/CLTB/FURIN/RAB8A/HLA-G/CCDC88A/OCRL/GOSR2/HLA-DRA/LRRK2/AP1G2/TEX261/IER3IP1/CLTCL1/STX5/HLA-C/SAR1A/ARF1/KDELR3/ZDHHC13/SCAP/COPG2/COL7A1/RHOQ/COPA/KDELR2/LMAN1/VTI1A/PEF1/SREBF2/AP2A1/TMED5/SEC23IP/RAB8B/ARCN1/AP1G1/VMA21/TMED4/HLA-DQB2/VTI1B/YIPF6/HLA-A/ATP7A/COPZ2/SCFD1/YIF1B/YIF1A/APP/ACR/ERGIC2/STK16/GJA1/SEC24A/SEC31B/SEC16B	81
CC	GO:0071556	integral component of lumenal side of endoplasmic reticulum membrane	17/7377	29/19717	0.01638	0.07288	0.05214	BCAP31/CD74/PKD2/HLA-F/SPPL2A/HLA-DPB1/HLA-DPA1/HLA-E/HLA-B/HLA-G/HLA-DRA/TAPBP/HLA-C/CANX/CALR/HLA-DQB2/HLA-A	17
CC	GO:0098553	lumenal side of endoplasmic reticulum membrane	17/7377	29/19717	0.01638	0.07288	0.05214	BCAP31/CD74/PKD2/HLA-F/SPPL2A/HLA-DPB1/HLA-DPA1/HLA-E/HLA-B/HLA-G/HLA-DRA/TAPBP/HLA-C/CANX/CALR/HLA-DQB2/HLA-A	17
CC	GO:0030175	filopodium	50/7377	104/19717	0.01667	0.07351	0.05258	MYO1G/VASP/EZR/ARF6/SPATA13/ARL4C/KITLG/ACPP/CIB1/DEF6/CBX6/IQGAP2/UBE2K/TWF2/RDX/MYO5A/BAIAP2/FZD9/ACTC1/CDK5/TUBB3/ACTA2/DMD/HLA-G/CYFIP1/MORN4/SYNE2/LCP1/ERMN/ITGA3/AP2A1/UNC5C/FSCN1/FMR1/MSN/MYO10/EPHB1/RUFY3/TBC1D10C/FGD4/ENAH/TRPV4/APP/DAG1/B4GALT1/FGF13/ACTA1/INPPL1/TENM2/NPTXR	50
CC	GO:0030426	growth cone	78/7377	171/19717	0.01672	0.07351	0.05258	RTN4R/DPYSL3/PINK1/TSC1/C9orf72/LRIG2/TIMP2/KLC1/CIB1/ORAI2/ALS2/HNRNPR/CBX6/PTPRO/TSHZ3/NDRG2/TWF2/PTK2B/MYO5A/SYAP1/STMN3/ITGA4/USP9X/CDK5/TRAK2/PAFAH1B1/TUBB3/CTSZ/ZPR1/DTNBP1/MAP3K12/LRP1/BASP1/LRRK2/CYFIP1/SETX/DICER1/GDPD5/TOR1A/NRP1/DISC1/DNM2/L1CAM/CCDC120/KIF20B/DCTN2/NDEL1/OLFM1/ITGA3/RASGRF1/CDK5R2/UNC5C/PREX1/FSCN1/DVL1/PSEN1/FMR1/YWHAE/KATNB1/EXOC4/RUFY3/LMTK2/KIF5B/TRAK1/HSP90AB1/ACAP3/TRPV4/APP/SNCA/SIGMAR1/SSH1/FGF13/BOC/TENM2/PTCH1/PCDH9/TRPV2/NPTXR	78
CC	GO:0000775	chromosome, centromeric region	87/7377	193/19717	0.01708	0.07447	0.05327	PPP2CA/NUP160/ZNF330/DYNC1LI1/CEBPB/CBX5/SPDL1/KAT2B/SUV39H2/REC8/SYCP3/CENPW/SIN3A/NUP85/SEH1L/CLIP1/ZNF276/PDS5A/CENPE/CBX1/NUP43/PAFAH1B1/DSCC1/KAT8/CENPT/CENPN/SKA2/SPAG5/MIS12/PPP2R5C/ZNF207/CENPC/PSEN2/CSNK1A1/CHAMP1/ZNFX1/NCAPD3/BUB3/IKZF1/SUV39H1/NDC80/BOD1L1/CBX3/ZWILCH/CTCF/CKAP5/DCTN2/NUP107/DSN1/NDEL1/PHF6/NUF2/INCENP/ZW10/ERCC6L/CENPK/KDM4D/DYNLT3/PPP1CC/PMF1/CLASP2/STAG3/RCC2/SS18L1/DNMT3A/PSEN1/FMR1/KIF2C/SMC3/SPC25/MTBP/SNAI1/CENPA/PKHD1/NUDCD2/STAG1/DYNC1LI2/FBXO28/CENPL/AURKA/CENPI/DCTN6/MIS18BP1/DCTN5/DAXX/BOD1/SKA3	87
CC	GO:0030427	site of polarized growth	80/7377	176/19717	0.01713	0.07447	0.05327	RTN4R/DPYSL3/PINK1/TSC1/C9orf72/LRIG2/TIMP2/KLC1/CIB1/ORAI2/ALS2/HNRNPR/CBX6/PTPRO/TSHZ3/HCLS1/NDRG2/TWF2/PTK2B/MYO5A/SYAP1/STMN3/ITGA4/USP9X/CDK5/TRAK2/PAFAH1B1/TUBB3/CTSZ/ZPR1/DTNBP1/MAP3K12/LRP1/BASP1/LRRK2/CYFIP1/SETX/DICER1/GDPD5/TOR1A/NRP1/DISC1/DNM2/L1CAM/CCDC120/KIF20B/DCTN2/PI4K2A/NDEL1/OLFM1/ITGA3/RASGRF1/CDK5R2/UNC5C/PREX1/FSCN1/DVL1/PSEN1/FMR1/YWHAE/KATNB1/EXOC4/RUFY3/LMTK2/KIF5B/TRAK1/HSP90AB1/ACAP3/TRPV4/APP/SNCA/SIGMAR1/SSH1/FGF13/BOC/TENM2/PTCH1/PCDH9/TRPV2/NPTXR	80
CC	GO:0005942	phosphatidylinositol 3-kinase complex	16/7377	27/19717	0.01727	0.07467	0.05342	SOCS3/ATG14/CISH/PIK3R3/SOCS5/SOCS6/PIK3R6/SOCS7/PIK3CD/SOCS1/PIK3CG/SLA2/VAC14/NRBF2/SOCS2/PIK3CB	16
CC	GO:0043025	neuronal cell body	209/7377	497/19717	0.01762	0.07546	0.05398	CRHBP/NQO1/NRGN/CCR2/RTN4R/CX3CR1/KCNN4/PRKAR2B/MAP1S/SOD1/SRD5A1/C9orf72/LRIG2/KLHL24/CAPN2/TIMP2/FLNA/MBP/CIB1/ALCAM/DENND1A/ALS2/UCHL1/SLC38A7/AGFG1/SLC2A3/P2RX7/LAMP1/KCNC4/EPHB2/ELOVL5/PVALB/CBX6/GIGYF2/APOE/ANXA3/CD22/LRP8/MAGOHB/TGFB1/KCNE3/DNAJB1/RAPGEF2/PTK2B/MYO5A/SYAP1/ROR2/INSR/STAU1/SCN1B/BAIAP2/ITGA4/NCF1/ITSN1/ACSL4/CDK5/SLC1A4/CASP3/TRAK2/ABL1/PURA/PAFAH1B1/FCHSD1/ZPR1/GDI1/RBM8A/AIF1/PMM2/S100B/ARHGEF2/STRN/LRP1/CNNM4/RAB8A/TMPRSS5/TRPM4/IL6ST/TRPM2/TTBK1/LRRK2/PPARGC1A/CYFIP1/ARC/CRTC1/MCRS1/PSEN2/ROGDI/GDPD5/PAM/PLK3/BMPR1A/NRP1/XRN1/L1CAM/ERMN/FUS/CHRNA10/DMWD/PI4K2A/RAB5A/KCNAB1/NDEL1/DAB1/CCR4/OLFM1/INPP5F/CTSV/RTN4RL1/CYBA/VTI1A/CYBB/KCNK2/PITX3/FZD5/CNR2/LPAR1/GOT2/ADA/CANX/KCNA2/CHRM2/YKT6/CHRNA4/EEF1A2/FLNB/NSMF/PPP1CA/UNC5C/MUL1/AMIGO1/CRIPT/TUBB4A/DVL1/SLC8A2/MAP1A/PRKAA1/PSEN1/FMR1/ASTN2/MAPK1/ENO2/DNER/PHAX/MAP2K4/VTI1B/RTN4RL2/KATNB1/MYO10/ITGA8/SRR/TGFB3/ADAM21/CAD/UBXN1/RUFY3/LMTK2/HTR5A/VIP/ATP7A/STRN3/RET/GRK4/TMEM50A/HSP90AB1/SPTBN2/RIN1/INHA/KNDC1/ATXN10/VPS16/KCND1/SYT4/PRKCZ/SNCAIP/NDUFS7/TBX21/SYT5/MTOR/HPN/AURKA/APP/GHRH/RTN4/SNCA/CX3CL1/IAPP/TOP1/P2RX2/AZIN2/EFNA2/KREMEN1/EFHC1/LRP4/CNKSR2/SLC8A3/PICALM/ENDOG/BMPR1B/CACNA1F/HTR3A/SIAH2/DPYSL5/NTSR1/KISS1/BMPR2/SYNPO/KNCN/NPTXR/ERCC8	209
CC	GO:0098798	mitochondrial protein complex	115/7377	262/19717	0.01778	0.07546	0.05398	C15orf48/CHCHD6/TIMM23B/IMMP1L/MRPS6/UQCRC2/BCKDK/NDUFA8/C12orf65/MRPL35/PDK2/MRPL45/NDUFC1/CLPX/CHCHD1/NDUFB11/APOO/DBT/MRPL40/MCU/MRPS30/MRPL34/NDUFS3/NDUFA3/DNAJC19/TIMM8B/MRPS16/TIMM17A/NDUFA11/MRPS14/CHCHD10/MRPL54/TIMM21/UQCR10/GRPEL1/AFG3L2/MRPL44/MRPL33/MCCC1/TIMM10B/MTX1/NDUFA4/IMMP2L/GRPEL2/COX4I2/NDUFA1/POLG/WDR93/BAX/MRPL51/HSD17B10/TOMM22/TOMM40L/PDK1/TOMM40/NDUFA10/MRPL49/MICU1/NDUFB1/MRPL3/NDUFB5/UQCRQ/SUCLG2/HADHA/MRPL42/TOMM20/VDAC1/DLAT/NDUFS1/DAP3/COA3/TIMM22/MRPS34/AGK/NDUFB8/DNAJC15/MRPL4/MRPS33/SUPV3L1/NDUFB6/MRPL20/BCKDHB/MRPL46/MRPS18B/MRPL24/MRPL36/TOMM5/NDUFB3/PMPCB/SDHA/MRPS15/MRPL48/BCKDHA/POLRMT/NDUFS7/NDUFV2/ND4/SDHD/MRPL41/UQCRB/PNPT1/MRPL2/NDUFB2/TRMT10C/MPV17L2/MRPS2/TIMM50/MRPS9/APOOL/NDUFS2/MICU2/NDUFA7/MRPL30/TIMM9/MRPS17	115
CC	GO:0098858	actin-based cell projection	93/7377	208/19717	0.01799	0.07546	0.05398	MYO1G/ICAM2/VASP/EZR/ARF6/AKR1B1/SPATA13/ARL4C/RHOC/SYTL1/KITLG/ACPP/CIB1/CD44/SCARB1/DEF6/S100P/PVALB/CBX6/IQGAP2/MPP1/UBE2K/TWF2/TGFB1/RDX/STARD10/MYO5A/HYAL2/BAIAP2/FZD9/ACTC1/CDK5/ATP6V1A/PAFAH1B1/TUBB3/ACTA2/ATP8B1/DMD/BBS2/HLA-G/ATP6V1B2/TMC2/KPTN/LRRK2/CYFIP1/MYO1C/CLIC4/WWOX/ENPP7/MORN4/SYNE2/LCP1/ERMN/ELMOD3/CTSV/PDGFA/ITGA3/TPRN/AP2A1/UNC5C/FSCN1/FMR1/IFT20/MSN/SLC4A7/MYO10/EXOC4/EPHB1/RUFY3/ATP7A/CLCA1/TBC1D10C/CNP/FGD4/ENAH/PTPRH/EPS8L2/TRPV4/APP/DAG1/B4GALT1/ATP6V1B1/CIB2/MYO15A/ANKS4B/FGF13/ESPNL/TMC1/ACTA1/INPPL1/TENM2/FCHSD2/NPTXR	93
CC	GO:0098573	intrinsic component of mitochondrial membrane	37/7377	74/19717	0.01806	0.07546	0.05398	SCO2/PINK1/CHCHD6/TIMM23B/SLC25A19/COX11/GDAP1/FIS1/TMEM70/APOO/MCU/ABCB6/TIMM17A/RHOT2/ETFDH/MPC2/CHCHD10/ABCB10/AFG3L2/ARMCX3/COX16/OXA1L/SFXN1/TOMM40/CPT1A/MICU1/PET100/TOMM20/COA3/MUL1/AGK/L2HGDH/BAK1/APOOL/MGARP/FUNDC1/TMEM177	37
CC	GO:0042611	MHC protein complex	15/7377	25/19717	0.01813	0.07546	0.05398	CD74/HLA-F/HLA-DPB1/HLA-DPA1/HLA-E/HLA-B/HLA-DMB/HLA-DOB/HLA-G/HLA-DRA/HLA-DMA/HLA-C/HLA-DQB2/HLA-A/HLA-DOA	15
CC	GO:0043202	lysosomal lumen	46/7377	95/19717	0.01819	0.07546	0.05398	FUCA1/ASAH1/HEXB/VCAN/PLBD2/CTSA/MANBA/CTSF/TPP1/CTSD/NAGLU/GM2A/NPC2/LIPA/CTSS/IDS/LGMN/LAMP2/CTSK/PSAP/CD1E/CD74/HEXA/CHID1/ARSB/SGSH/GALC/MAN2B1/GNS/EPDR1/CSPG4/CTSB/GLA/IDUA/GUSB/HPSE/CTSV/BCAN/ARSA/GPC2/GAA/NEU1/SMPD1/GPC4/SDC3/MAN2B2	46
CC	GO:0005637	nuclear inner membrane	30/7377	58/19717	0.01823	0.07546	0.05398	LMNB1/TRA2B/SUN2/P2RX7/TMEM43/NRM/ITPR1/UNC50/ATP11B/RNF13/IFI27/EMD/SIRT1/DPY19L4/TM7SF2/PSEN2/P2RX1/TMEM201/CBX3/ZMPSTE24/DPY19L2/SPAG4/ATP1B4/LEMD3/NPAP1/ERN1/P2RX2/SIGMAR1/DPY19L2P2/P2RX5	30
CC	GO:0008021	synaptic vesicle	86/7377	191/19717	0.01823	0.07546	0.05398	SLC40A1/CTTNBP2/APBA1/STX7/STX11/SYT11/SEC22B/STXBP5/LAMP1/WDR7/SLC2A8/SYPL1/UNC13B/SGTA/WFS1/RABAC1/TPRG1L/VAMP3/PDE4B/CLCN3/SCAMP1/SYNGR2/TMEM230/C16orf70/CLTB/DTNBP1/CLN3/SEMA4C/RAB8A/LRRK2/SYT6/PSEN2/ATG9A/ROGDI/TOR1A/DNM1/DISC1/RAB5A/KIAA1107/NDEL1/STX16/MTMR2/VDAC2/VTI1A/PTPRN2/SLC17A5/DNM1L/VDAC1/RAB8B/ICA1/PSEN1/SYNGR3/SYNGR4/RAB3A/RAB35/STX12/SYPL2/VTI1B/SYT9/ZNRF1/SYT1/OPRD1/RAB3B/SYT2/VAMP1/DOC2A/SYT4/SNCAIP/SYT5/SCAMP5/PICK1/BRSK1/APP/RAB3D/SNCA/SLC9B2/ATP6V1B1/APH1A/PICALM/SYN3/RAB26/BIN1/AMPH/DMXL2/LGI3/SV2B	86
CC	GO:0035770	ribonucleoprotein granule	99/7377	223/19717	0.01874	0.07615	0.05448	NFKBIZ/USP3/TUBA1A/ZFP36/C9orf72/BARD1/CKAP4/CHTOP/SQSTM1/G3BP2/AGO2/MOV10/TDRD6/GIGYF2/ACTB/PCBP1/SARNP/PSMA4/PITPNM1/STAU1/HNRNPK/MBNL1/GABPB1/RBM4/SAMD4B/PIWIL4/HABP4/TAF5L/LARP4/DDX19B/DHX9/DCP1B/DCP2/ZC3H12D/ICOSLG/SYMPK/NSUN2/BLNK/MOV10L1/RAC1/APOBEC3G/EIF2S1/CAPRIN1/CDK9/POLI/APOBEC3C/MAP1LC3C/TSTD1/ATXN2/LSM14A/SUMO1/PUM2/DDX3X/BTBD1/DCPS/PSMC3/ATXN2L/SHB/TRIM21/XRN1/HELZ/CPEB1/EDC4/AGO1/DDX1/TDRD7/TNRC6B/GRB7/TNRC6A/LIG4/POLR2D/DYRK3/LARP4B/CNOT7/CLOCK/FMR1/SOCS1/DIS3L2/EIF4E/PSMA2/EID1/ARNTL/INA/HNRNPA3/CTSG/PSMC2/SNCAIP/VCP/SAMD4A/TOP1/KPNB1/GHR/ROCK2/EIF4ENIF1/PABPC4L/TARDBP/SNRPG/UPF1/FASTKD5	99
CC	GO:0044798	nuclear transcription factor complex	90/7377	201/19717	0.01887	0.07615	0.05448	KLF4/JUNB/FOS/VDR/STAT3/JUND/NFYC/THRA/PPARD/SMAD2/CEBPB/CBFB/LDB1/ERCC4/POU2F1/ATF4/MXD3/NFATC3/HIF1A/TLE1/NR1H2/E2F6/HNRNPAB/HYAL2/GTF2E1/SOX21/CEBPA/ASCL2/TCF12/TLE4/TAF5L/CCNH/TAF11/NR1D2/HMGA1/TAF12/GTF2F2/SNAPC1/MED17/CREB1/SFPQ/TAF1B/TAF5/BCL9L/WWOX/GTF2H4/PTOV1/RXRA/NFATC1/NFATC2/ERCC1/NR1H3/TAF1D/GTF2F1/NFAT5/MED4/TEAD2/ARNT/TAF6L/MED25/E2F4/PPARA/TBPL1/ASCL3/KAT2A/GTF2A1/GTF3C3/TCF7L2/ERCC2/TAF9B/TAF4/MED8/MXI1/BDP1/RB1/CARM1/SOX12/TBP/CD3EAP/MED26/SOX4/SNAPC4/TADA3/NR1H4/E2F8/ATF6B/TAF7/FOXH1/SOX7/MYF6	90
CC	GO:0002116	semaphorin receptor complex	8/7377	11/19717	0.01899	0.07615	0.05448	PLXNB2/PLXNC1/PLXNA1/NRP1/PLXND1/NRP2/PLXNA3/PLXNA2	8
CC	GO:0005885	Arp2/3 protein complex	8/7377	11/19717	0.01899	0.07615	0.05448	ACTR2/ARPC1A/ARPC1B/ARPC5L/ACTR3B/ACTR3/ARPC4/ARPC2	8
CC	GO:0019774	proteasome core complex, beta-subunit complex	8/7377	11/19717	0.01899	0.07615	0.05448	PSMB9/PSMB8/PSMB10/PSMB1/PSMB3/PSMB5/PSMB2/PSMB4	8
CC	GO:0031932	TORC2 complex	8/7377	11/19717	0.01899	0.07615	0.05448	PRR5/MLST8/SESN1/TELO2/MAPKAP1/MTOR/SESN2/TTI1	8
CC	GO:0031306	intrinsic component of mitochondrial outer membrane	13/7377	21/19717	0.01967	0.07847	0.05614	PINK1/GDAP1/FIS1/ABCB6/RHOT2/ARMCX3/TOMM40/CPT1A/TOMM20/MUL1/BAK1/MGARP/FUNDC1	13
CC	GO:0008250	oligosaccharyltransferase complex	9/7377	13/19717	0.02017	0.07956	0.05691	DAD1/STT3A/KRTCAP2/OST4/RPN2/STT3B/TUSC3/TMEM258/DDOST	9
CC	GO:0016281	eukaryotic translation initiation factor 4F complex	9/7377	13/19717	0.02017	0.07956	0.05691	OTUD6B/EIF4E3/EIF4B/EIF4E2/EIF4H/EIF4G2/EIF4G3/EIF4G1/EIF4E	9
CC	GO:0031045	dense core granule	12/7377	19/19717	0.02025	0.07956	0.05691	CRHBP/SOD1/ADAM8/VPS13A/BACE2/SYT9/SYT1/OPRD1/SYT2/SYT4/SYT5/SPX	12
CC	GO:0000176	nuclear exosome (RNase complex)	11/7377	17/19717	0.02061	0.07987	0.05713	DIS3L/WDR74/EXOSC2/EXOSC7/MPHOSPH6/EXOSC9/EXOSC3/EXOSC6/EXOSC8/C1D/EXOSC5	11
CC	GO:0000778	condensed nuclear chromosome kinetochore	10/7377	15/19717	0.02064	0.07987	0.05713	REC8/MIS12/CENPC/NDC80/DSN1/NUF2/CENPK/PMF1/CENPA/MIS18BP1	10
CC	GO:0090533	cation-transporting ATPase complex	10/7377	15/19717	0.02064	0.07987	0.05713	ATP1A1/SLC9A1/ATP1B2/ATP1B3/FXYD1/ATP1B1/ATP1B4/FXYD2/ATP1A2/ATP12A	10
CC	GO:0097542	ciliary tip	24/7377	45/19717	0.02132	0.08211	0.05874	IFT172/IFT57/KIF3B/KIFAP3/DYNLL2/IFT80/WDR19/IFT46/CYLD/IFT52/HSPB11/DYNC2LI1/DYNLRB1/DYNLRB2/IFT20/WDR60/IFT22/WDR35/TRAF3IP1/IFT74/SMO/TTC30B/IFT81/RP1	24
CC	GO:0032839	dendrite cytoplasm	18/7377	32/19717	0.02322	0.08853	0.06333	SOD1/ABHD13/ZC3H14/WLS/ABHD12/BAIAP2/TRAK2/PURA/SFPQ/LRRK2/FLOT2/KCNAB1/ADA/CANX/MAPK1/MAP2K4/KIF17/GABARAPL1	18
CC	GO:1905348	endonuclease complex	18/7377	32/19717	0.02322	0.08853	0.06333	ZFP36/AGO2/RPP38/DHX9/RPP25/RPP14/CLP1/DICER1/LAS1L/TARBP2/HSD17B10/AGO1/RPP40/RPPH1/POP7/DROSHA/ERN1/TRMT10C	18
CC	GO:1904115	axon cytoplasm	29/7377	57/19717	0.02601	0.09869	0.0706	SOD1/BLOC1S2/ZC3H14/UCHL1/KIF3B/HIF1A/HSPB1/AP3M2/TRAK2/PAFAH1B1/DTNBP1/BLOC1S6/KIF4A/ARL8A/BLOC1S3/NDEL1/BLOC1S1/BLOC1S4/AP3B1/MAP1A/FMR1/KIF1B/AP3M1/KIF5B/TRAK1/KIF1C/MGARP/ARL8B/TRIM46	29
CC	GO:1904724	tertiary granule lumen	28/7377	55/19717	0.02815	0.1063	0.07602	ASAH1/QPCT/PTPN6/ARMC8/CTSD/TIMP2/CTSS/PPBP/CST3/TNFAIP6/CFP/HBB/OSCAR/PTX3/ALDOC/QSOX1/ALDOA/IDH1/PRSS3/CYFIP1/ILF2/CNN2/MMP9/YPEL5/LRG1/TCN1/HP/CDA	28
CC	GO:0070603	SWI/SNF superfamily-type complex	37/7377	76/19717	0.02901	0.1087	0.07779	BAZ1A/CHRAC1/ANP32E/BPTF/ZBTB7A/MTA3/RUVBL2/RUVBL1/MBD3/RBBP7/RBBP4/ARID1B/UCHL5/SMARCA1/BRD8/INO80C/TFPT/MCRS1/ACTR5/HDAC2/KAT5/YY1/DPF2/RSF1/PBRM1/BRD9/ING3/SS18L1/PHF10/SS18/SMARCC2/RB1/SMARCA5/NCR1/SMARCC1/MTA2/ACTL6A	37
CC	GO:0030660	Golgi-associated vesicle membrane	53/7377	114/19717	0.02908	0.1087	0.07779	NRGN/MCFD2/KLHL12/SEC22B/CD59/CD74/ITM2B/AFTPH/SAR1B/HLA-F/SPPL2A/CNIH3/COPE/HLA-DPB1/HLA-DPA1/GOPC/HLA-E/HLA-B/ARFGAP3/TMED10/CLTB/HLA-G/GOSR2/HLA-DRA/AP1G2/CLTCL1/STX5/HLA-C/SAR1A/KDELR3/ZDHHC13/SCAP/COPG2/RHOQ/COPA/KDELR2/LMAN1/VTI1A/PEF1/SREBF2/AP2A1/SEC23IP/ARCN1/AP1G1/VMA21/HLA-DQB2/VTI1B/HLA-A/COPZ2/GJA1/SEC24A/SEC31B/SEC16B	53
CC	GO:0044450	microtubule organizing center part	82/7377	185/19717	0.03132	0.1165	0.08337	HYLS1/HSPA6/BLOC1S2/BBS5/FLOT1/FOPNL/ODF2/RAN/CETN3/CEP164/PCM1/CEP104/CEP131/CBY1/SASS6/CAPG/PLK2/PDE4B/SFI1/CDK5RAP2/KIAA0753/RP2/HERC2/TUBD1/CEP76/SPAG5/RAB8A/CCDC78/CCDC88A/CNTLN/KIF2A/CCHCR1/LCK/IFT52/BBS4/CEP55/AKNA/PLA2G3/SPICE1/BCCIP/HOOK3/PARP3/KIF24/CCDC120/TUBGCP3/CKAP5/CEP152/MKS1/CCDC151/CEP63/DYRK3/TUBG2/CCDC92/BRCA1/TUBGCP5/CETN1/CETN2/BBS9/CEP19/IFT20/CEP83/WDR60/KATNB1/FGFR1OP/CCDC13/POC5/LRRCC1/CEP120/DZIP1L/TOPORS/AURKA/TTBK2/CEP78/UXT/CCDC66/CEP85/POC1B/C2CD3/ALMS1/TOP2A/WRAP73/CCNF	82
CC	GO:0042629	mast cell granule	13/7377	22/19717	0.03184	0.1179	0.08434	ANXA1/LYN/AKR1B1/LAT2/RASGRP1/S100A13/PLA2G3/PIK3CD/CXCR2/SRGN/NR4A3/PIK3CG/LAT	13
CC	GO:0005776	autophagosome	44/7377	93/19717	0.03199	0.1179	0.08435	SRPX/C9orf72/NCOA4/ATG14/SQSTM1/WDR81/LAMP2/LAMP1/TICAM1/TBC1D5/RAB23/MAP1LC3A/FTL/RAB24/TP53INP2/TEX264/TMEM230/CLN3/VPS33A/WIPI1/LRRK2/MAP1LC3C/PEG3/RPN2/ATG9A/ZFYVE1/TBC1D17/TRIM21/UBQLN2/MEFV/VPS18/VTI1A/ULK1/SH3GLB1/ATG16L2/GABARAPL1/VPS16/OPTN/SNAP29/DAPK2/NRBF2/NBR1/MCOLN3/ATG12	44
CC	GO:0005667	transcription factor complex	154/7377	365/19717	0.0329	0.1207	0.08633	KLF4/JUNB/EPAS1/FOS/VDR/ARNTL2/SPI1/MEF2A/NR4A2/SKI/RBPJ/STAT3/JUND/NFYC/THRA/PDLIM1/CREG1/PPARD/SMAD5/SMAD7/EYA3/SMAD2/CEBPB/CBFB/ATF5/LDB1/ERCC4/REL/POU2F1/ATF4/RELA/HCLS1/CDK4/MXD3/NFATC3/SIN3A/LMO2/SRA1/HIF1A/TLE1/NR1H2/E2F6/HNRNPAB/HYAL2/GTF2E1/SOX21/CEBPA/ASCL2/TCF12/TLE4/TAF5L/CCNH/TAF11/SATB2/NR1D2/HMGA1/TAF12/GTF2F2/AHR/SUB1/ELMSAN1/SNAPC1/MED17/CREB1/MED27/RFX3/SFPQ/ABT1/TAF1B/TAF5/BCL9L/TAL1/TCF7L1/ETS1/ARNT2/CREM/WWOX/GTF2H4/PTOV1/MYOG/KAT5/RXRA/IVNS1ABP/NFATC1/NFATC2/ERCC1/YY1/NR2E3/NR1H3/BEX1/TLE6/RBPJL/KLF5/TAF1D/GTF2F1/NFAT5/MED4/TEAD2/NPAS4/ARNT/TAF6L/MED25/E2F4/PMF1/NAA16/PPARA/TBPL1/ASCL3/CLOCK/KAT2A/GTF2A1/GTF3C3/TCF7L2/ERCC2/TAF9B/XRCC6/RBL2/HNF1B/TAF4/ARNTL/HOXA10/PBX2/NR4A3/MED8/MXI1/BDP1/HSP90AB1/RB1/CARM1/SOX12/FOXF2/MEIS1/PITX1/TBP/NAA15/CD3EAP/MED26/SOX4/ZFP42/SNAPC4/FOXF1/TADA3/MTA2/RCOR3/NR1H4/PBX3/E2F8/ATF6B/POU3F1/TAF7/FOXH1/SOX7/MYF6/AIP	154
CC	GO:0005839	proteasome core complex	12/7377	20/19717	0.03362	0.121	0.08657	PSMB9/PSMB8/PSMA5/PSMB10/PSMA1/PSMA4/PSMB1/PSMB3/PSMB5/PSMA2/PSMB2/PSMB4	12
CC	GO:0031082	BLOC complex	12/7377	20/19717	0.03362	0.121	0.08657	BLOC1S2/HPS4/HPS1/HPS3/DTNBP1/BLOC1S6/BLOC1S3/PI4K2A/BLOC1S1/BLOC1S4/STX12/HPS6	12
CC	GO:0035371	microtubule plus-end	12/7377	20/19717	0.03362	0.121	0.08657	CLIP1/MYO5A/CDK5RAP2/MAPRE1/SPAG5/MAPRE2/CKAP5/KIF2C/CLIP2/SKAP1/SLAIN2/NCKAP5L	12
CC	GO:0044232	organelle membrane contact site	12/7377	20/19717	0.03362	0.121	0.08657	MBOAT7/ESYT2/ATG14/ACSL4/STARD3NL/PDZD8/RAB32/RAB38/ZFYVE1/CANX/TOMM20/SERAC1	12
CC	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	43/7377	91/19717	0.03448	0.1236	0.08839	FYN/LYN/KCNAB2/HCK/GNAI3/GNB1/GNA15/ESYT2/GNG5/RGS1/CYTH1/S100A6/KRAS/GNG7/GNAQ/PTK2B/SYAP1/SNX18/FGR/PTK6/LCK/CYLD/GNG2/GNAI2/KCNAB1/OSBPL2/FER/FRK/CNR2/ATP2A2/MYZAP/STAC2/GNA13/SNX5/DTNA/GNG11/MATK/KCNIP1/GNG12/RHOA/SNX9/SHANK3/GNA11	43
CC	GO:0017053	transcriptional repressor complex	40/7377	84/19717	0.03539	0.1246	0.08915	JAZF1/SKI/RBPJ/DR1/DDX20/CBX5/CTBP2/ZBTB7A/SIN3A/MTA3/TFAP4/MBD3/RBBP7/RELB/MIER1/RBBP4/HMGB1/SIRT1/ETV3/CCND1/ZNF224/HDAC2/NCOR1/CORO2A/SUV39H1/N4BP2L2/HDAC4/LIN9/INSM2/HEY2/TBL1X/SMARCA5/RLIM/ZBTB16/MTA2/AKIRIN2/C1D/RCOR3/TBX15/HDGF	40
CC	GO:0044215	other organism	37/7377	77/19717	0.03613	0.1246	0.08915	GBP2/NUP62/NMT2/NUP160/NUP214/VPS37B/RAN/AXL/NUP85/SEH1L/GBP4/NUP43/CD209/VPS37C/POM121/RAB29/BICD1/NUP88/TSG101/PI4K2A/TOP2B/NUP107/UBAP1/UBC/LMAN1/IFIT1/CNOT7/NUP93/NUP205/FMR1/KPNA1/NUP50/GBP6/KPNB1/POM121C/AAAS/TOP2A	37
CC	GO:0044216	other organism cell	37/7377	77/19717	0.03613	0.1246	0.08915	GBP2/NUP62/NMT2/NUP160/NUP214/VPS37B/RAN/AXL/NUP85/SEH1L/GBP4/NUP43/CD209/VPS37C/POM121/RAB29/BICD1/NUP88/TSG101/PI4K2A/TOP2B/NUP107/UBAP1/UBC/LMAN1/IFIT1/CNOT7/NUP93/NUP205/FMR1/KPNA1/NUP50/GBP6/KPNB1/POM121C/AAAS/TOP2A	37
CC	GO:0044217	other organism part	37/7377	77/19717	0.03613	0.1246	0.08915	GBP2/NUP62/NMT2/NUP160/NUP214/VPS37B/RAN/AXL/NUP85/SEH1L/GBP4/NUP43/CD209/VPS37C/POM121/RAB29/BICD1/NUP88/TSG101/PI4K2A/TOP2B/NUP107/UBAP1/UBC/LMAN1/IFIT1/CNOT7/NUP93/NUP205/FMR1/KPNA1/NUP50/GBP6/KPNB1/POM121C/AAAS/TOP2A	37
CC	GO:0033643	host cell part	10/7377	16/19717	0.03678	0.1246	0.08915	GBP2/AXL/GBP4/RAB29/BICD1/PI4K2A/LMAN1/CNOT7/FMR1/GBP6	10
CC	GO:0035098	ESC/E(Z) complex	10/7377	16/19717	0.03678	0.1246	0.08915	PHF19/EZH2/TRIM37/RBBP7/RBBP4/SIRT1/HDAC2/DNMT3L/AEBP2/EZH1	10
CC	GO:0070822	Sin3-type complex	10/7377	16/19717	0.03678	0.1246	0.08915	SIN3A/RBBP4/SIN3B/SUDS3/BRMS1L/SAP130/HDAC2/NCOR1/HEY2/BRMS1	10
CC	GO:0005643	nuclear pore	42/7377	89/19717	0.03717	0.1246	0.08915	NXF1/NUP62/NUP160/NUP214/ENY2/AGFG1/RAN/MX2/NUP85/NXT1/CETN3/SEH1L/BICD2/NUP43/TMEM33/MVP/SNUPN/DDX19B/POM121/XPOT/MYO1C/SUMO1/NUP88/NUP107/NPIPA1/NXT2/NUP62CL/EIF5A/NUP93/CETN2/NUP205/IPO7/KPNA1/NUP50/PARP11/MCM3AP/PCID2/NPAP1/KPNB1/XPO4/POM121C/AAAS	42
CC	GO:0005875	microtubule associated complex	68/7377	152/19717	0.03787	0.1246	0.08915	PEA15/MAP1S/KLC1/DYNC1LI1/HAUS8/KIF9/LRP8/KIF3B/KIFAP3/MAP4/RANBP9/DYNLL2/STAU1/CENPE/KIFC3/APPBP2/PAFAH1B1/KIF4A/RABGAP1/TTBK1/KIF2A/DNAL1/KIF16B/HAUS2/DISC1/MEFV/DNAI2/KIF24/DNAH17/KIF20B/DCTN2/DYNC2LI1/NDEL1/KIF13A/DYNLRB1/CCDC65/DYNLRB2/PXN/KIF27/DYNLT3/DNAL4/HAUS5/HAUS1/MAP1A/YWHAE/DNAI1/KIF2C/KIF17/WDR60/KATNB1/CLIP2/KIF1B/KIF5B/KLC4/SNX4/DYNC1LI2/KLC2/DNAH10/KIF1C/TOPORS/AURKA/KIF12/DCTN6/KLC3/DNAH8/DNAH2/RP1/KIF14	68
CC	GO:0031010	ISWI-type complex	7/7377	10/19717	0.03787	0.1246	0.08915	BAZ1A/CHRAC1/BPTF/RBBP4/SMARCA1/RSF1/SMARCA5	7
CC	GO:0031313	extrinsic component of endosome membrane	7/7377	10/19717	0.03787	0.1246	0.08915	ANXA1/WDR91/SNX10/WDR81/GRIPAP1/SNX5/SNX16	7
CC	GO:0033162	melanosome membrane	9/7377	14/19717	0.03791	0.1246	0.08915	GPNMB/DTNBP1/RAB32/RAB38/GPR143/DCT/MREG/OCA2/RAB27A	9
CC	GO:0038201	TOR complex	9/7377	14/19717	0.03791	0.1246	0.08915	PRR5/MLST8/AKT1S1/SESN1/TELO2/MAPKAP1/MTOR/SESN2/TTI1	9
CC	GO:0045009	chitosome	9/7377	14/19717	0.03791	0.1246	0.08915	GPNMB/DTNBP1/RAB32/RAB38/GPR143/DCT/MREG/OCA2/RAB27A	9
CC	GO:0045239	tricarboxylic acid cycle enzyme complex	9/7377	14/19717	0.03791	0.1246	0.08915	BCKDK/DBT/OGDH/DHTKD1/FH/SUCLG2/KAT2A/BCKDHB/BCKDHA	9
CC	GO:0090741	pigment granule membrane	9/7377	14/19717	0.03791	0.1246	0.08915	GPNMB/DTNBP1/RAB32/RAB38/GPR143/DCT/MREG/OCA2/RAB27A	9
CC	GO:0016234	inclusion body	39/7377	82/19717	0.03819	0.1246	0.08915	PINK1/NXF1/STRADB/TDP2/SQSTM1/DVL2/SLFN11/AGL/CABIN1/ATF4/EDEM1/TRIM37/GYS1/XRN2/CCZ1B/KLF8/DBF4B/FGR/PSMC4/CLU/LRRK2/TRIM50/SYNE2/STUB1/ATXN3/PSEN1/CCZ1/POLD1/ATXN1/HSP90AB1/PSMC5/GPX1/PRKCQ/PICK1/SNCA/ZBTB14/BAG5/PICALM/ATXN3L	39
CC	GO:0005890	sodium:potassium-exchanging ATPase complex	8/7377	12/19717	0.03841	0.1246	0.08915	ATP1A1/ATP1B2/ATP1B3/FXYD1/ATP1B1/ATP1B4/FXYD2/ATP1A2	8
CC	GO:0017119	Golgi transport complex	8/7377	12/19717	0.03841	0.1246	0.08915	COG8/DNAJC28/COG4/COG6/COG2/COG1/COG7/GOLGA3	8
CC	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	8/7377	12/19717	0.03841	0.1246	0.08915	DDB1/GLMN/CDKN1B/DET1/DTL/RBX1/TRPC4AP/ERCC8	8
CC	GO:0071006	U2-type catalytic step 1 spliceosome	8/7377	12/19717	0.03841	0.1246	0.08915	MAGOHB/SNRNP200/RBM8A/ISY1/CWC22/PRPF8/CWC25/PRPF19	8
CC	GO:0071012	catalytic step 1 spliceosome	8/7377	12/19717	0.03841	0.1246	0.08915	MAGOHB/SNRNP200/RBM8A/ISY1/CWC22/PRPF8/CWC25/PRPF19	8
CC	GO:0098978	glutamatergic synapse	147/7377	349/19717	0.03848	0.1246	0.08915	NRGN/RTN4R/FYN/CTTNBP2/APBA1/ATP2B4/PRKAR2B/ARF6/LYN/DNM3/WNT5A/STAT3/SLITRK4/RAB11A/FLNA/PPM1H/PACSIN2/ABHD6/FLOT1/ABHD17C/JAK2/CTBP2/EPHB2/IL1RAP/FXYD6/APOE/GSK3B/PTPRO/KCNA3/RELA/ACTB/PPP3CB/STXBP1/PFN1/DNAJB1/UNC13B/GRIPAP1/ARF4/PTK2B/MYO5A/DYNLL2/ACTN1/STAU1/CORO1A/NRG1/BAIAP2/FBXO45/FBXL20/ITSN1/FZD9/ABR/ACTC1/USP46/CDK5/ARHGAP22/HRAS/PURA/OPHN1/PAK2/GRIP1/DTNBP1/NUMB/ARHGEF2/RAP1A/DLGAP4/RAB8A/NPTN/HOMER1/RAC1/NDRG1/SPTBN1/CAMKV/LRRK2/FLOT2/SYT6/ARC/CRTC1/ADCY1/SPARC/BCR/PRR7/ARF1/SH3GL1/ARPC5L/DNM1/P2RX1/NRP1/ABLIM3/ADORA2B/SPARCL1/VPS18/NAPA/DNM2/NRP2/RGS14/SHISA9/NTNG2/GRASP/ADAM22/SYNGAP1/SHANK1/BCAN/CANX/CHRM2/GRIN2C/PPP1CC/PLCB1/PPP1CA/C1QBP/LIN7C/FZD4/PLEKHA5/DVL1/CBLN1/P2RY4/PPFIA3/YWHAE/KPNA1/CDH10/EIF4E/EPHB1/SYT1/PIN1/SPTBN2/IL1RAPL1/VAMP1/ARPC2/SYT4/PRKCZ/GPC4/CADPS2/VCP/MTOR/RHOA/DAG1/RNF216/GSG1L/WNT7A/CNKSR2/CLSTN3/SYN3/P2RY1/HTR3A/DLGAP3/GHRL/SYNPO/NPTXR	147
CC	GO:1990752	microtubule end	16/7377	29/19717	0.03896	0.1256	0.08987	CLIP1/MYO5A/SVIL/CDK5RAP2/MAPRE1/SPAG5/MAPRE2/ASPM/CKAP5/KIF2C/CLIP2/SKAP1/SLAIN2/MISP/NAV3/NCKAP5L	16
CC	GO:0016605	PML body	46/7377	99/19717	0.04032	0.1295	0.09264	ELF4/SKI/TDP2/RNF111/SQSTM1/CBX5/NFE2/TRIM16/SMC5/ZNF451/SMC6/MAPK7/RPA1/ISG20/TP53INP2/SP100/NSMCE2/PML/SIRT1/CDK9/TDG/PPARGC1A/SUMO1/RGS14/RFWD3/RDM1/ZMYM2/HIPK1/ATR/USP7/TCF7L2/MKNK2/ARNTL/TOPBP1/HIPK3/RNF4/UBE2I/RB1/TERT/MTOR/TOPORS/ZBTB16/CHFR/DAXX/EIF4ENIF1/TENM2	46
CC	GO:0090734	site of DNA damage	35/7377	73/19717	0.04219	0.1349	0.09652	MAD2L2/PARP9/HUS1B/CBX5/SLFN11/ACTR2/ZBTB7A/SMC5/RNF138/SMC6/RPA1/CBX1/SETMAR/ARPC1A/XRCC5/SAMHD1/ADPRHL2/SMCHD1/SMARCAD1/POLH/PARP3/CBX3/RFWD3/TIMELESS/KDM4D/ACTR3/ARPC4/PRPF19/ARPC2/VCP/APLF/WDR76/AUNIP/WAS/OARD1	35
CC	GO:0099023	tethering complex	32/7377	66/19717	0.04289	0.1358	0.09712	TNFAIP2/EXOC6B/VPS41/EXOC1/COG8/TRAPPC5/DNAJC28/VPS33A/HOOK2/SH3BP1/HOOK3/VPS18/TRAPPC9/VPS51/COG4/VPS52/ZW10/COG6/TRAPPC2L/TRAPPC3/EXOC3L1/COG2/EXOC4/COG1/COG7/VPS16/TRAPPC8/GOLGA3/NBAS/VPS8/TRAPPC11/EXOC2	32
CC	GO:0044853	plasma membrane raft	50/7377	109/19717	0.04297	0.1358	0.09712	MYOF/ITGAM/EZR/ATP2B4/ATP1A1/HCK/PTGS2/TFPI/PACSIN2/FLOT1/SCARB1/JAK2/HMOX1/LCP2/LRP8/CTNNA1/INSR/CLN3/P2RY12/LRRK2/FLOT2/MLC1/ATP1B3/SELPLG/BMPR1A/FXYD1/ATP1B1/MS4A1/PRKACA/ADD3/RANGRF/CORO1C/F2R/SPRED1/ORAI1/CAV3/MAPK1/CHRNB2/SKAP1/PRTN3/KCNMA1/DAG1/SMPD2/CD8A/LRP4/ATP1A2/SMO/ADCYAP1R1/PTCH1/BMPR2	50
CC	GO:1902911	protein kinase complex	50/7377	109/19717	0.04297	0.1358	0.09712	CDKN2D/CDKN1A/ACVR2B/C9orf72/CCND3/SIK1/CCND2/TBC1D5/CDK4/ZBTB7A/INSR/IKBKG/CCNG1/IGF1R/CDK5/CCNH/SIK2/ATG13/PHKB/CCND1/ACVR1B/CDK9/IFIT5/PHKG1/GTF2H4/PRKAG2/LAS1L/BCCIP/CCNE1/PCNA/CCNK/MAP3K5/CDK5R2/ULK1/CCNY/PRKAA1/CCNA1/SMCR8/ERCC2/PRKAG1/RB1/CCNA2/CCNT1/ERN1/CCNG2/CCNB3/CHUK/SESN2/CCNF/PRKAB1	50
CC	GO:0090575	RNA polymerase II transcription factor complex	72/7377	163/19717	0.04474	0.1408	0.1007	JUNB/FOS/VDR/STAT3/JUND/NFYC/THRA/PPARD/SMAD2/CEBPB/CBFB/LDB1/ERCC4/POU2F1/ATF4/MXD3/HIF1A/TLE1/NR1H2/E2F6/HNRNPAB/HYAL2/GTF2E1/CEBPA/ASCL2/TCF12/TLE4/TAF5L/CCNH/TAF11/NR1D2/HMGA1/TAF12/GTF2F2/MED17/CREB1/SFPQ/TAF5/BCL9L/WWOX/GTF2H4/RXRA/ERCC1/NR1H3/GTF2F1/MED4/TEAD2/ARNT/TAF6L/E2F4/PPARA/TBPL1/ASCL3/KAT2A/GTF2A1/TCF7L2/ERCC2/TAF9B/TAF4/MED8/MXI1/RB1/CARM1/TBP/MED26/TADA3/NR1H4/E2F8/ATF6B/TAF7/FOXH1/MYF6	72
CC	GO:0030864	cortical actin cytoskeleton	42/7377	90/19717	0.04503	0.1411	0.101	MYADM/PLS1/CAPN2/MLPH/FLOT1/HFE/AKAP13/PVALB/ACTR2/HCLS1/RDX/CAPZA2/GMFG/CORO1A/CAP1/FCHSD1/CAPZA1/MED28/SPTBN1/FLOT2/MYH9/WIPF2/COTL1/CFL1/ACTR3/LASP1/BIN3/MYZAP/SPTA1/LLGL1/SPTBN2/WIPF1/EPB41L2/MISP/CAP2/TRPV4/SNX9/CIB2/SHROOM1/WAS/LANCL2/KNCN	42
CC	GO:0046930	pore complex	13/7377	23/19717	0.0486	0.1517	0.1085	PLEKHA7/PDZD11/BCL2/BAX/TOMM40L/TSPAN33/TOMM40/VDAC2/VDAC1/CD34/VDAC3/BAK1/C7	13
CC	GO:0035580	specific granule lumen	30/7377	62/19717	0.05027	0.1563	0.1118	QPCT/PTPN6/ARMC8/RETN/GHDC/CTSD/TIMP2/ACAA1/VCL/NFKB1/CFP/OSCAR/PTX3/QSOX1/CTSZ/ERP44/CHI3L1/CYFIP1/ILF2/CNN2/HPSE/LRG1/TOLLIP/FRK/LRRC7/TCN1/NEU1/HP/KPNB1/RAB27A	30
CC	GO:0031312	extrinsic component of organelle membrane	24/7377	48/19717	0.05062	0.1566	0.112	ANXA1/WDR91/SNX10/ATG14/WDR81/SGTA/GRIPAP1/COQ7/COQ5/PML/COQ3/TOR1A/ZFYVE1/COQ6/NOA1/ULK1/SNX5/DOC2A/MMP27/VAC14/ATP6V1B1/COQ4/GOLGA3/SNX16	24
CC	GO:0005871	kinesin complex	27/7377	55/19717	0.05077	0.1566	0.112	KLC1/KIF9/KIF3B/KIFAP3/CENPE/KIFC3/PAFAH1B1/KIF4A/KIF2A/KIF16B/DISC1/KIF24/KIF20B/NDEL1/KIF13A/KIF27/YWHAE/KIF2C/KIF17/KIF1B/KIF5B/KLC4/KLC2/KIF1C/KIF12/KLC3/KIF14	27
CC	GO:0005680	anaphase-promoting complex	12/7377	21/19717	0.05221	0.1591	0.1138	MAD2L2/UBE2S/CDC23/ANAPC5/ANAPC7/UBE2C/CDC26/ANAPC4/CDC27/CDC20/ANAPC11/ANAPC13	12
CC	GO:0098533	ATPase dependent transmembrane transport complex	12/7377	21/19717	0.05221	0.1591	0.1138	ATP1A1/ABCD4/SLC9A1/ABCB6/ATP1B2/ATP1B3/FXYD1/ATP1B1/ATP1B4/FXYD2/ATP1A2/ATP12A	12
CC	GO:0044448	cell cortex part	80/7377	184/19717	0.05237	0.1591	0.1138	MYADM/EZR/PLS1/GYPC/CAPN2/FLNA/MLPH/ACTN4/FLOT1/CTBP2/HFE/TNFAIP2/AKAP13/PVALB/EXOC6B/PKD2/ACTR2/HCLS1/MPP1/ACTB/EXOC1/RDX/UNC13B/CAPZA2/GMFG/CORO1A/CAP1/ENO1/FCHSD1/CTSZ/EMD/SAPCD2/CLTB/C2CD2L/CAPZA1/MAPRE1/MED28/SH3BP1/SPTBN1/ARV1/FLOT2/MYH9/TPM4/WIPF2/COTL1/CFL1/DMTN/ACTR3/LASP1/NSMF/CLASP2/MYL12B/GPSM2/BIN3/MYZAP/HAMP/TCHP/EXOC3L1/PPFIA3/EPB41/SLC4A1/EXOC4/EPB42/SPTA1/LLGL1/SPTBN2/WIPF1/EPB41L2/PRKCZ/MISP/CAP2/TRPV4/SNX9/CIB2/SHROOM1/RIMS2/WAS/LANCL2/EXOC2/KNCN	80
CC	GO:0009897	external side of plasma membrane	163/7377	393/19717	0.05243	0.1591	0.1138	CD69/CD163L1/KCNJ5/ITGAM/IL2RG/CCR2/RTN4R/CX3CR1/IL27RA/ANXA1/ITGA5/CAPN2/ECE1/FCN1/FCGRT/TNFRSF14/S1PR1/IL13RA1/CD40/CD1C/CD2/FLOT1/BTN2A1/ALCAM/ACKR3/FOLR2/CXCL9/PTPRC/P2RX7/CD1E/HFE/LAMP1/CD59/TNF/CD74/GSR/CXCL10/LILRB1/CXCL12/TMEM123/IL7R/CSF2RA/CD226/CD36/HEG1/SPA17/IL3RA/INSR/ENOX2/HLA-F/NCAM1/HYAL2/FLT3LG/TLR4/IL2RB/HLA-E/HLA-B/CD209/CLCN3/ABCA1/CLEC12B/CD3D/LDLR/CD1B/CLPTM1/P2RY12/ICOSLG/TNFRSF11A/ATP6AP2/IL6ST/IL1R1/HLA-G/TRBC1/CXCR1/CDH5/CD200R1/ITGAE/IGSF21/CCR5/CTLA4/HLA-C/BTN3A2/PDCD1LG2/P2RX1/GFRA2/BMPR1A/FCER2/GFRA4/GFRA3/DNAI2/MS4A1/ABCG1/CCR6/BTN3A3/LAG3/ITGA2/CD3G/CD1D/IL12RB1/CD1A/CXCR6/CCR4/CTSV/CD274/RTN4RL1/EBI3/ICOS/BTN2A2/ITGA3/MAP3K5/ADA/CALR/CHRNA4/ULBP2/DMBT1/CCR3/CXCR2/CD276/TFRC/ADAM9/TLR8/BTN3A1/IL13RA2/ANTXR2/CHRNB2/CNTFR/RTN4RL2/TNFRSF4/HLA-A/SCART1/STAB2/CD5/BCAM/CSF3R/PKHD1/CD34/CD4/TNFRSF13C/F3/IL12B/MICA/CD33/GPC4/CD80/DAG1/B4GALT1/CD83/ENG/CXCR3/CD244/CD8A/GHR/TMC1/CCR7/CD3E/PDCD1/ACKR2/CCRL2/CD24/GRIA2/MOG/IGHD/MCAM	163
CC	GO:0032391	photoreceptor connecting cilium	20/7377	39/19717	0.05374	0.1625	0.1162	SPATA7/IFT57/KIFAP3/WDR19/IFT52/RPGRIP1/BBS4/NPHP4/MAK/LCA5/TBCC/FAM161A/CETN1/CETN2/IFT20/KIF17/PCDHB13/PCDHB15/TOPORS/RP1	20
CC	GO:0000776	kinetochore	60/7377	135/19717	0.05538	0.1668	0.1193	NUP160/DYNC1LI1/CBX5/SPDL1/KAT2B/REC8/CENPW/SIN3A/NUP85/SEH1L/CLIP1/ZNF276/CENPE/NUP43/PAFAH1B1/KAT8/CENPT/CENPN/SKA2/SPAG5/MIS12/ZNF207/CENPC/PSEN2/CSNK1A1/CHAMP1/BUB3/NDC80/BOD1L1/ZWILCH/CKAP5/DCTN2/NUP107/DSN1/NDEL1/PHF6/NUF2/INCENP/ZW10/ERCC6L/CENPK/DYNLT3/PPP1CC/PMF1/CLASP2/SS18L1/PSEN1/KIF2C/SPC25/MTBP/CENPA/NUDCD2/DYNC1LI2/FBXO28/CENPI/DCTN6/MIS18BP1/DCTN5/BOD1/SKA3	60
CC	GO:0016592	mediator complex	19/7377	37/19717	0.0584	0.1752	0.1253	MED29/MED10/MED11/THRAP3/MED15/MED17/MED27/MED28/MED16/MED13/MED9/MED4/MED30/MED25/CCNC/HAVCR2/MED8/MED24/MED26	19
CC	GO:0070461	SAGA-type complex	15/7377	28/19717	0.05981	0.1783	0.1275	ENY2/SUPT7L/KAT2B/ATXN7L3/TAF5L/TAF12/TAF5/TAF6L/KAT2A/TAF9B/TAF4/USP22/TADA3/SUPT20H/TAF7	15
CC	GO:0031143	pseudopodium	10/7377	17/19717	0.05989	0.1783	0.1275	CAPN2/ACTN4/KLHL41/ARRB1/ACTN1/RAF1/MYOZ1/MAPK1/MSN/CNP	10
CC	GO:0000793	condensed chromosome	95/7377	223/19717	0.06261	0.1846	0.132	SUN2/EID3/DYNC1LI1/CCNB1IP1/CEBPB/HUS1B/SPDL1/REC8/RAD1/SYCP3/CENPW/SMC5/NUP85/KIFAP3/SMC6/SEH1L/ZNF276/CENPE/NUP43/SETMAR/CCDC155/RGS12/NSMCE2/CENPT/CENPN/HMGB1/SKA2/SPAG5/MIS12/RCC1/ZNF207/CENPC/SMC2/CSNK1A1/CHAMP1/BANF1/NCAPD3/BUB3/AKAP8/SUV39H1/NDC80/MLH1/BOD1L1/CBX3/HMGB2/ZWILCH/CTCF/CKAP5/NUP107/DSN1/ADD3/NDEL1/PHF6/NUF2/INCENP/ZW10/CHMP1A/LIG4/ERCC6L/CENPK/DYNLT3/PPP1CC/PMF1/CLASP2/STAG3/BRCA1/SS18L1/SYCE3/KIF2C/SMC3/SPC25/RNF212B/MKI67/RAD9A/TOPBP1/CENPA/UBE2I/FANCD2/NUDCD2/STAG1/ESRRB/SMARCA5/FBXO28/AURKA/STAG3L3/DCTN6/TOP3B/MIS18BP1/DCTN5/RRS1/BOD1/HORMAD1/TOP2A/SKA3/L3MBTL1	95
CC	GO:0030672	synaptic vesicle membrane	47/7377	104/19717	0.06272	0.1846	0.132	SYT11/LAMP1/SYPL1/UNC13B/SGTA/WFS1/TPRG1L/VAMP3/SCAMP1/SYNGR2/C16orf70/CLTB/DTNBP1/SEMA4C/LRRK2/SYT6/RAB5A/STX16/PTPRN2/SLC17A5/DNM1L/ICA1/SYNGR3/SYNGR4/RAB3A/RAB35/STX12/SYPL2/SYT9/ZNRF1/SYT1/OPRD1/RAB3B/SYT2/VAMP1/DOC2A/SYT4/SYT5/SCAMP5/SNCA/SLC9B2/ATP6V1B1/SYN3/RAB26/AMPH/DMXL2/SV2B	47
CC	GO:0099501	exocytic vesicle membrane	47/7377	104/19717	0.06272	0.1846	0.132	SYT11/LAMP1/SYPL1/UNC13B/SGTA/WFS1/TPRG1L/VAMP3/SCAMP1/SYNGR2/C16orf70/CLTB/DTNBP1/SEMA4C/LRRK2/SYT6/RAB5A/STX16/PTPRN2/SLC17A5/DNM1L/ICA1/SYNGR3/SYNGR4/RAB3A/RAB35/STX12/SYPL2/SYT9/ZNRF1/SYT1/OPRD1/RAB3B/SYT2/VAMP1/DOC2A/SYT4/SYT5/SCAMP5/SNCA/SLC9B2/ATP6V1B1/SYN3/RAB26/AMPH/DMXL2/SV2B	47
CC	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex	9/7377	15/19717	0.06382	0.185	0.1323	ZZZ3/DR1/KAT2B/MBIP/KAT2A/UBAP2L/POLE4/TADA3/WDR5	9
CC	GO:0030122	AP-2 adaptor complex	9/7377	15/19717	0.06382	0.185	0.1323	FCHO1/FCHO2/TBC1D5/AP2A2/KIAA1107/AP2S1/AP2A1/AP2M1/PICALM	9
CC	GO:0031011	Ino80 complex	9/7377	15/19717	0.06382	0.185	0.1323	RUVBL2/RUVBL1/UCHL5/INO80C/TFPT/MCRS1/ACTR5/YY1/ACTL6A	9
CC	GO:0033202	DNA helicase complex	9/7377	15/19717	0.06382	0.185	0.1323	RUVBL2/RUVBL1/UCHL5/INO80C/TFPT/MCRS1/ACTR5/YY1/ACTL6A	9
CC	GO:0000307	cyclin-dependent protein kinase holoenzyme complex	21/7377	42/19717	0.06492	0.1875	0.1341	CDKN2D/CDKN1A/CCND3/CCND2/CDK4/CCNG1/CCNH/CCND1/CDK9/BCCIP/CCNE1/PCNA/CCNK/CCNY/CCNA1/RB1/CCNA2/CCNT1/CCNG2/CCNB3/CCNF	21
CC	GO:0000781	chromosome, telomeric region	70/7377	161/19717	0.06587	0.1895	0.1356	SUN2/EID3/MCM6/MCM2/CBX5/NABP1/EZH2/HAT1/ERCC4/ALYREF/DOT1L/SMC5/SMC6/ORC5/RPA1/CBX1/DDB1/SP100/HNRNPA2B1/PURA/CCDC155/SIRT7/WRNIP1/TEP1/NSMCE2/XRCC5/PML/SMCHD1/NAT10/PTGES3/ATM/SETX/NHP2/RAD17/PCNA/XRCC1/CBX3/ERCC1/THOC2/GAR1/TOX4/ORC4/LIG4/THOC5/DCLRE1A/PPP1CC/PPP1CA/ATR/THOC6/SSB/MCM5/RTEL1/TELO2/ACD/CTC1/POLD1/XRCC6/DCLRE1C/PPP1CB/MEN1/NLRP2/ORC3/TERT/CDC73/POT1/EZH1/WDR82/FEN1/RECQL4/UPF1	70
CC	GO:0031253	cell projection membrane	143/7377	345/19717	0.06666	0.1911	0.1367	PKD2L1/VASP/EZR/APPL2/ARF6/ITGA5/BBS5/DIAPH1/SPATA13/RASGRP2/GNB1/PLEKHA1/SYTL1/PACSIN2/CIB1/WLS/CD44/TTC8/SLC22A5/SCARB1/EVC/FGD5/SHOC2/KCNC4/SLC7A11/C2CD5/S100P/TESC/PKD2/DPP4/ATF4/LIMA1/DHRS3/DOCK8/CYBRD1/TLN1/PLEK2/PAK1/CD36/ARF4/PLEKHO1/ARL13B/INSR/MFSD10/NAPEPLD/DDX58/FZD9/FGR/CLTB/CSPG4/AIF1/ARHGEF2/PLB1/P2RY12/MAPRE1/TAS2R4/EHD1/ATP8B1/PDE6G/SLC22A12/DMD/BBS2/HLA-G/RAC1/SPTBN1/IQCE/PLAUR/ITLN1/MYO1C/IFIT5/SH3YL1/BBS4/TCTN2/SYNE2/LCP1/PLXND1/DNM2/TPM1/INPP5K/MTMR6/SHISA9/NME1/THEM4/CFL1/KANK1/BBS7/PEX19/SLC46A1/SLC5A6/PLEK/ITGA3/DMTN/CORO1C/KCNA2/SLC26A4/ABCA7/CLASP2/ADAM17/MXRA8/SPRY2/FSCN1/BBS9/TMEM231/GNA13/RAB35/GUCY2D/MSN/MYO10/ITGA8/ATP7A/PCDHB13/MTMR9/TBC1D10C/GRK4/OPRD1/GABARAPL1/EHD3/HSP90AB1/GPR161/PHLPP2/PSD4/ARPC2/SNAP29/TCTN3/PTPRH/EPS8L2/RHOA/TRPV4/GABRA4/B4GALT1/TIRAP/ARHGEF4/ASAP1/SHISA8/SMO/SHANK3/NCKAP1/PTCH1/MACF1/WWC1/PSD3/OPN4/PTPRJ	143
CC	GO:0001741	XY body	8/7377	13/19717	0.0676	0.1916	0.1371	BIRC2/UBE2A/SIN3B/PBX4/SUMO1/DNMT3A/SMARCC1/UBE2B	8
CC	GO:0032045	guanyl-nucleotide exchange factor complex	8/7377	13/19717	0.0676	0.1916	0.1371	C9orf72/RASGRP3/RAP1A/ELMO1/ULK1/SMCR8/KNDC1/RGP1	8
CC	GO:0071014	post-mRNA release spliceosomal complex	8/7377	13/19717	0.0676	0.1916	0.1371	CWF19L2/CRNKL1/SYF2/SNRNP200/CWF19L1/ISY1/HNRNPM/CCDC12	8
CC	GO:0005814	centriole	61/7377	139/19717	0.06857	0.1937	0.1386	HYLS1/HSPA6/FOPNL/ODF2/RAN/CETN3/CEP164/PCM1/CEP104/CBY1/SASS6/CAPG/PLK2/SFI1/KIAA0753/RP2/HERC2/TUBD1/CEP76/RAB8A/CCDC78/CCDC88A/CNTLN/KIF2A/CCHCR1/IFT52/BBS4/CEP55/AKNA/PLA2G3/SPICE1/BCCIP/PARP3/KIF24/CCDC120/TUBGCP3/CEP152/MKS1/CCDC151/CEP63/CCDC92/CETN1/CETN2/CEP19/IFT20/CEP83/FGFR1OP/POC5/LRRCC1/CEP120/DZIP1L/TOPORS/AURKA/TTBK2/CEP78/POC1B/C2CD3/ALMS1/TOP2A/WRAP73/CCNF	61
CC	GO:0080008	Cul4-RING E3 ubiquitin ligase complex	17/7377	33/19717	0.06915	0.1946	0.1392	DCAF8/DDB1/GLMN/RNF7/CDKN1B/DET1/DTL/DCAF13/DDB2/DCAF15/DCAF10/DCAF12/CUL4B/DCAF7/RBX1/TRPC4AP/ERCC8	17
CC	GO:0044455	mitochondrial membrane part	97/7377	229/19717	0.06939	0.1946	0.1392	SCO2/LYN/PINK1/C15orf48/CHCHD6/TIMM23B/IMMP1L/SLC25A19/UQCRC2/COX11/GDAP1/NDUFA8/NDUFC1/FIS1/COQ7/TMEM70/COQ5/NDUFB11/APOO/MCU/NDUFS3/ABCB6/NDUFA3/DNAJC19/TIMM17A/RHOT2/NDUFA11/ETFDH/MPC2/COQ3/CHCHD10/ABCB10/TIMM21/UQCR10/GRPEL1/BDH1/AFG3L2/LRRK2/ARMCX3/TIMM10B/COX7A2L/MTX1/NDUFA4/IMMP2L/GRPEL2/COX4I2/NDUFA1/WDR93/TOMM22/COX16/TOMM40L/OXA1L/SFXN1/COX15/TOMM40/CPT1A/NDUFA10/COQ6/CISD1/MICU1/NDUFB1/NOA1/PET100/NDUFB5/UQCRQ/TOMM20/NDUFS1/COA3/TIMM22/MUL1/AGK/NDUFB8/DNAJC15/SURF1/NDUFB6/L2HGDH/TOMM5/NDUFB3/SDHA/NDUFS7/NDUFV2/ND4/SDHD/UQCRB/COQ4/NDUFB2/TIMM50/BAK1/APOOL/NNT/NDUFS2/MGARP/MICU2/NDUFA7/FUNDC1/TMEM177/COX7B	97
CC	GO:0005652	nuclear lamina	7/7377	11/19717	0.07092	0.1968	0.1407	LMNB1/LMNA/EIF6/PRR14/NARF/SUV39H1/PCNA	7
CC	GO:0034663	endoplasmic reticulum chaperone complex	7/7377	11/19717	0.07092	0.1968	0.1407	HSPA5/SDF2L1/PDIA6/DNAJC10/HSP90B1/HYOU1/PPIB	7
CC	GO:0045240	dihydrolipoyl dehydrogenase complex	7/7377	11/19717	0.07092	0.1968	0.1407	BCKDK/DBT/OGDH/DHTKD1/KAT2A/BCKDHB/BCKDHA	7
CC	GO:0000777	condensed chromosome kinetochore	47/7377	105/19717	0.07338	0.2028	0.1451	DYNC1LI1/SPDL1/REC8/CENPW/NUP85/SEH1L/ZNF276/CENPE/NUP43/CENPT/CENPN/SKA2/SPAG5/MIS12/ZNF207/CENPC/CSNK1A1/CHAMP1/BUB3/NDC80/BOD1L1/ZWILCH/CKAP5/NUP107/DSN1/NDEL1/PHF6/NUF2/INCENP/ZW10/ERCC6L/CENPK/DYNLT3/PPP1CC/PMF1/CLASP2/SS18L1/KIF2C/SPC25/CENPA/NUDCD2/FBXO28/DCTN6/MIS18BP1/DCTN5/BOD1/SKA3	47
CC	GO:1902554	serine/threonine protein kinase complex	40/7377	88/19717	0.07445	0.2051	0.1467	CDKN2D/CDKN1A/ACVR2B/C9orf72/CCND3/CCND2/TBC1D5/CDK4/ZBTB7A/IKBKG/CCNG1/CDK5/CCNH/ATG13/PHKB/CCND1/ACVR1B/CDK9/IFIT5/PHKG1/GTF2H4/BCCIP/CCNE1/PCNA/CCNK/CDK5R2/ULK1/CCNY/CCNA1/SMCR8/ERCC2/RB1/CCNA2/CCNT1/ERN1/CCNG2/CCNB3/CHUK/SESN2/CCNF	40
CC	GO:0000790	nuclear chromatin	155/7377	377/19717	0.07481	0.2053	0.1469	KLF4/JUNB/KLF2/USP3/SPI1/MEF2A/IRF1/BAZ1A/STAT6/STAT3/JUND/RAD51AP1/PPARD/CHRAC1/ALKBH1/STAT1/SMAD2/MYC/CEBPB/CBX5/LDB1/EZH2/HAT1/UHRF1/ZEB2/RELA/ACTB/ANP32E/BPTF/ZBTB7A/SIN3A/HIF1A/NCOA3/MTA3/PCGF2/SRF/HNRNPK/MBD1/RUVBL2/RUVBL1/CBX1/MBD3/TCF12/KAT7/RBBP7/SIRT7/APTX/DFFA/KAT8/DHX9/CBX7/RBBP4/UBE2A/HMGB1/BUD31/CREB1/RFX3/SIRT1/TIPIN/ETV3/ARID1B/UCHL5/SIN3B/SMARCA1/BRD8/SUDS3/CDK9/TAF5/INO80C/PPARGC1A/RCC1/CITED2/TAL1/UHRF2/TFPT/CENPC/MCRS1/BRMS1L/TNKS1BP1/CALCOCO1/IPO4/SAP130/NCAPD3/MUC1/IKZF1/ACTR5/HDAC2/NCOR1/TRIM24/KAT5/RXRA/HNRNPC/NACC2/RAD17/XRCC1/NFATC1/CBX3/HMGB2/NFATC2/YY1/DPF2/NR1H3/TTI2/ASXL2/SSRP1/SWI5/RSF1/PBRM1/BRD9/TIMELESS/FER/RING1/NSMF/E2F4/PLCB1/ING3/SS18L1/DNMT3A/HEY2/KAT2A/PHF10/TCF7L2/TELO2/SS18/TAF4/NUFIP1/SMARCC2/ASF1A/CENPA/NASP/CHAF1A/ASXL3/RB1/MEN1/SMARCA5/TBP/NCR1/ZFP42/POLR3GL/SMARCC1/MCMBP/TRNP1/MTA2/ACTL6A/UBE2B/NRIP1/HMGB4/NUCKS1/NR1H4/TARDBP/KAT6B/TTI1/MEF2C/FOXH1/BRMS1	155
CC	GO:0097038	perinuclear endoplasmic reticulum	12/7377	22/19717	0.07666	0.2093	0.1497	FYN/CAPN2/CISD2/BCAP31/TRIM13/CREB3L2/CLU/DGAT2/SYT6/GDPD5/CYBA/CYBB	12
CC	GO:0000784	nuclear chromosome, telomeric region	55/7377	125/19717	0.07681	0.2093	0.1497	SUN2/MCM6/MCM2/CBX5/NABP1/HAT1/ERCC4/ALYREF/ORC5/RPA1/CBX1/DDB1/SP100/PURA/SIRT7/WRNIP1/XRCC5/PML/SMCHD1/NAT10/ATM/NHP2/PCNA/XRCC1/CBX3/ERCC1/THOC2/GAR1/TOX4/ORC4/LIG4/THOC5/DCLRE1A/PPP1CC/PPP1CA/ATR/THOC6/SSB/MCM5/TELO2/ACD/CTC1/POLD1/XRCC6/DCLRE1C/PPP1CB/MEN1/NLRP2/ORC3/TERT/CDC73/POT1/WDR82/FEN1/UPF1	55
CC	GO:0031256	leading edge membrane	73/7377	170/19717	0.07922	0.2152	0.1539	MYO1G/VASP/EZR/APPL2/ITGA5/DIAPH1/SPATA13/RASGRP2/PLEKHA1/PACSIN2/CIB1/WLS/CD44/FGD5/KCNC4/C2CD5/TESC/DPP4/ATF4/DOCK8/TLN1/PLEK2/PAK1/ARF4/PLEKHO1/INSR/DDX58/FGR/CSPG4/AIF1/ARHGEF2/RAC1/SPTBN1/MYO1C/IFIT5/SH3YL1/SYNE2/LCP1/PLXND1/DNM2/TPM1/INPP5K/MTMR6/SHISA9/NME1/THEM4/CFL1/KANK1/PLEK/CORO1C/KCNA2/ABCA7/CLASP2/ADAM17/SPRY2/ITGA8/MTMR9/OPRD1/GABARAPL1/PSD4/EPS8L2/RHOA/TRPV4/GABRA4/TIRAP/ARHGEF4/SHISA8/NCKAP1/MACF1/WWC1/PSD3/AMPH/PTPRJ	73
CC	GO:0005905	clathrin-coated pit	32/7377	69/19717	0.07953	0.2152	0.154	FCHO1/FCHO2/ACKR3/TBC1D5/SH3BP4/ARRB1/SYNJ1/ITSN1/LRP10/CLTB/LDLR/LRP1/OCRL/CLTCL1/SPHK1/AP2A2/DNM2/KIAA1107/AP2S1/INPP5F/NECAP2/DNM1L/AP2A1/CEMIP/AP1S3/TFRC/RAB35/LRP12/AP2M1/APP/PICALM/FCHSD2	32
CC	GO:0030125	clathrin vesicle coat	15/7377	29/19717	0.08215	0.2195	0.1571	FCHO1/FCHO2/TBC1D5/AFTPH/CLTB/AP1G2/CLTCL1/AP2A2/KIAA1107/AP2S1/NECAP2/AP2A1/AP1G1/AP2M1/PICALM	15
CC	GO:0032838	plasma membrane bounded cell projection cytoplasm	88/7377	208/19717	0.08238	0.2195	0.1571	SPATA7/ATG7/SOD1/AKR1B1/BLOC1S2/BBS5/ABHD13/ZC3H14/WLS/ABHD12/ATG14/UCHL1/IFT172/IFT57/KIF3B/TULP3/KIFAP3/HIF1A/MAP4/HSPB1/ARL13B/WDR11/BAIAP2/AP3M2/TRAK2/PURA/PAFAH1B1/AK8/DTNBP1/BLOC1S6/KIF4A/SFPQ/DNAL1/LRRK2/FLOT2/RPGRIP1/WDR66/ARL8A/MAK/BLOC1S3/WDPCP/DNAI2/DNAH17/PRKACA/KCNAB1/DYNC2LI1/NDEL1/RSPH9/BBS7/TTLL3/CCDC151/CCDC65/ADA/CANX/BLOC1S1/BLOC1S4/LCA5/AP3B1/RSPH6A/TUBB4A/MAP1A/FMR1/MAPK1/DNAI1/MAP2K4/KIF17/KIF1B/AP3M1/MAATS1/KIF5B/TRAK1/GABARAPL1/WDR35/TRAF3IP1/DNAH10/KIF1C/NEK4/CCDC63/EFHC1/SPAG17/DNAH8/TTC30B/MGARP/DNAH2/RP1/GAS8/ARL8B/TRIM46	88
CC	GO:0030132	clathrin coat of coated pit	11/7377	20/19717	0.08334	0.2195	0.1571	FCHO1/FCHO2/TBC1D5/SYNJ1/CLTB/AP2A2/KIAA1107/AP2S1/AP2A1/AP2M1/PICALM	11
CC	GO:0071682	endocytic vesicle lumen	11/7377	20/19717	0.08334	0.2195	0.1571	APOE/HBB/SPARC/SCGB3A2/CALR/HSP90B1/APOA1/GNLY/HP/HYOU1/MPO	11
CC	GO:0071782	endoplasmic reticulum tubular network	11/7377	20/19717	0.08334	0.2195	0.1571	RNF41/ATL1/RAB3GAP1/EMD/PARP16/C2CD2L/ARV1/ATL3/REEP5/RTN4/KPNB1	11
CC	GO:0009295	nucleoid	21/7377	43/19717	0.08339	0.2195	0.1571	HADHB/MTERF1/CLPX/SSBP1/DBT/TFB1M/MTERF2/UQCC2/SLC25A5/SHMT2/POLG/TEFM/VDAC2/ACADVL/HADHA/VDAC1/SUPV3L1/TERT/POLRMT/TRMT10C/FASTKD5	21
CC	GO:0016235	aggresome	21/7377	43/19717	0.08339	0.2195	0.1571	STRADB/TDP2/SQSTM1/DVL2/SLFN11/CABIN1/EDEM1/TRIM37/XRN2/CCZ1B/KLF8/DBF4B/FGR/TRIM50/SYNE2/PSEN1/CCZ1/POLD1/PRKCQ/PICK1/ZBTB14	21
CC	GO:0042645	mitochondrial nucleoid	21/7377	43/19717	0.08339	0.2195	0.1571	HADHB/MTERF1/CLPX/SSBP1/DBT/TFB1M/MTERF2/UQCC2/SLC25A5/SHMT2/POLG/TEFM/VDAC2/ACADVL/HADHA/VDAC1/SUPV3L1/TERT/POLRMT/TRMT10C/FASTKD5	21
CC	GO:0008180	COP9 signalosome	18/7377	36/19717	0.08383	0.2199	0.1573	HSPA6/FLOT1/HSPA5/BASP1/TESPA1/MYH9/WDR6/GRB2/HSPA1L/THEMIS/COPS2/HSP90AB1/EPB41L2/COPS8/GPS1/AMOTL1/COPS3/LAT	18
CC	GO:0032154	cleavage furrow	26/7377	55/19717	0.08606	0.225	0.161	KLHDC8B/ICAM2/ARF6/RAB11A/RHOC/PSTPIP1/SPIRE1/LIMA1/RDX/PITPNM1/SVIL/RAB11FIP4/CENPC/MYH9/CEP55/HMCN1/MYLK/PPP1CC/PKN2/STAMBP/MASTL/MEN1/RHOA/SSH1/ZFYVE19/HTR3A	26
CC	GO:0097431	mitotic spindle pole	14/7377	27/19717	0.08968	0.2337	0.1672	MAPKBP1/CDK5RAP2/SPAG5/ASPM/BCCIP/YPEL5/KIF20B/KATNA1/FAM161A/GPSM2/SMC3/STAG1/AURKA/IK	14
CC	GO:0090723	growth cone part	10/7377	18/19717	0.09063	0.2343	0.1676	PAFAH1B1/CYFIP1/DISC1/NDEL1/ITGA3/FMR1/YWHAE/EXOC4/APP/TRPV2	10
CC	GO:0015030	Cajal body	35/7377	77/19717	0.0907	0.2343	0.1676	PRPF4/TRIM22/ISG20/COIL/HABP4/TOE1/HNRNPA2B1/ZPR1/U2AF1/NOLC1/PRPF3/SNRPC/EAF1/FBL/NHP2/LSG1/GAR1/RDM1/SCARNA17/USPL1/DDX46/SMNDC1/NPAT/TGS1/PRPF31/SART1/FMR1/AK6/PHAX/FBLL1/HINFP/ICE1/EFTUD2/NOP10/ZNF473	35
CC	GO:0043596	nuclear replication fork	20/7377	41/19717	0.09079	0.2343	0.1676	RPA1/ETAA1/PRIM2/PURA/POLD4/POLD2/BCAS2/SMARCAD1/TIPIN/PCNA/TIMELESS/GINS4/POLD1/POLA1/PRPF19/POLA2/SMARCA5/TOP1/TONSL/ZRANB3	20
CC	GO:0098636	protein complex involved in cell adhesion	17/7377	34/19717	0.09145	0.2351	0.1682	ITGAM/LYN/ITGA5/ITGB7/ITGB5/ITGAD/ITGAL/TSPAN32/ITGA4/ITGA7/ITGA11/ITGAE/CTLA4/ITGA2/ITGA3/ITGA8/CD80	17
CC	GO:0030120	vesicle coat	27/7377	58/19717	0.09713	0.2485	0.1778	FCHO1/KLHL12/FCHO2/TBC1D5/AFTPH/SAR1B/COPE/ARFGAP3/CLTB/AP1G2/CLTCL1/SAR1A/AP2A2/COPG2/COPA/KIAA1107/AP2S1/NECAP2/PEF1/AP2A1/ARCN1/AP1G1/COPZ2/AP2M1/PICALM/SEC24A/SEC31B	27
CC	GO:0097346	INO80-type complex	13/7377	25/19717	0.09802	0.2485	0.1778	ANP32E/RUVBL2/RUVBL1/UCHL5/BRD8/INO80C/TFPT/MCRS1/ACTR5/KAT5/YY1/ING3/ACTL6A	13
CC	GO:0030128	clathrin coat of endocytic vesicle	9/7377	16/19717	0.09857	0.2485	0.1778	FCHO1/FCHO2/TBC1D5/AP2A2/KIAA1107/AP2S1/AP2A1/AP2M1/PICALM	9
CC	GO:0030479	actin cortical patch	9/7377	16/19717	0.09857	0.2485	0.1778	ACTR2/CAPZA2/GMFG/CAPZA1/WIPF2/ACTR3/BIN3/WIPF1/WAS	9
CC	GO:0042613	MHC class II protein complex	9/7377	16/19717	0.09857	0.2485	0.1778	CD74/HLA-DPB1/HLA-DPA1/HLA-DMB/HLA-DOB/HLA-DRA/HLA-DMA/HLA-DQB2/HLA-DOA	9
CC	GO:0061645	endocytic patch	9/7377	16/19717	0.09857	0.2485	0.1778	ACTR2/CAPZA2/GMFG/CAPZA1/WIPF2/ACTR3/BIN3/WIPF1/WAS	9
CC	GO:1990204	oxidoreductase complex	49/7377	112/19717	0.09904	0.2489	0.178	CBR4/UQCRC2/BCKDK/NDUFA8/PDK2/NDUFC1/NDUFB11/NCF4/DBT/NCF2/NDUFS3/NCF1/NDUFA3/NDUFA11/OGDH/UQCR10/NOXA1/DHTKD1/NDUFA4/NDUFA1/WDR93/PDK1/NDUFA10/PDHB/CYBA/NDUFB1/CYBB/RRM2/NDUFB5/UQCRQ/DLAT/NDUFS1/NDUFB8/KAT2A/PDHA2/NDUFB6/BCKDHB/NDUFB3/SDHA/BCKDHA/NDUFS7/NDUFV2/ND4/SDHD/UQCRB/NDUFB2/P4HA1/NDUFS2/NDUFA7	49
CC	GO:0005901	caveola	36/7377	80/19717	0.09957	0.2493	0.1784	MYOF/ATP2B4/ATP1A1/HCK/PTGS2/TFPI/PACSIN2/FLOT1/SCARB1/JAK2/HMOX1/LRP8/CTNNA1/INSR/CLN3/P2RY12/LRRK2/FLOT2/MLC1/ATP1B3/BMPR1A/FXYD1/ATP1B1/RANGRF/CORO1C/F2R/SPRED1/CAV3/MAPK1/KCNMA1/SMPD2/ATP1A2/SMO/ADCYAP1R1/PTCH1/BMPR2	36
CC	GO:0000407	phagophore assembly site	16/7377	32/19717	0.09986	0.2493	0.1784	ATG7/ULK2/ATG14/SQSTM1/ATG101/ATG13/WIPI1/ATG9A/ZFYVE1/ATG2B/WDR45B/ULK1/STX12/TRAPPC8/NBR1/ATG12	16
CC	GO:0097731	9+0 non-motile cilium	50/7377	115/19717	0.1061	0.2611	0.1868	SPATA7/LYAR/GNB1/SHOC2/IFT57/DHRS3/TULP3/KIFAP3/GNAQ/MYO5A/NAPEPLD/WDR19/PDE6G/OCRL/RPGR/IFT52/RPGRIP1/BBS4/NPHP4/MAK/OPN3/BBS7/LCA5/TBCC/FAM161A/CETN1/CETN2/C11orf74/MERTK/IFT20/GUCY2D/KIF17/PPEF2/NXNL1/PCDHB13/GRK4/INHA/PHLPP2/PCDHB15/TOPORS/CIB2/TULP1/CCDC66/PDC/CACNA1F/RAB27A/GNA11/RP1/OPN4/PTGS1	50
CC	GO:0005744	TIM23 mitochondrial import inner membrane translocase complex	8/7377	14/19717	0.1072	0.2611	0.1868	TIMM23B/DNAJC19/TIMM17A/TIMM21/GRPEL1/GRPEL2/DNAJC15/TIMM50	8
CC	GO:0030677	ribonuclease P complex	8/7377	14/19717	0.1072	0.2611	0.1868	RPP38/RPP25/RPP14/HSD17B10/RPP40/RPPH1/POP7/TRMT10C	8
CC	GO:0033276	transcription factor TFTC complex	8/7377	14/19717	0.1072	0.2611	0.1868	TAF5L/TAF12/TAF5/KAT2A/TAF9B/TAF4/TADA3/TAF7	8
CC	GO:0033646	host intracellular part	8/7377	14/19717	0.1072	0.2611	0.1868	GBP2/GBP4/RAB29/BICD1/LMAN1/CNOT7/FMR1/GBP6	8
CC	GO:0036020	endolysosome membrane	8/7377	14/19717	0.1072	0.2611	0.1868	LDLR/AP2A2/AP2S1/AP2A1/TLR8/CLEC16A/TLR3/AP2M1	8
CC	GO:0043656	intracellular region of host	8/7377	14/19717	0.1072	0.2611	0.1868	GBP2/GBP4/RAB29/BICD1/LMAN1/CNOT7/FMR1/GBP6	8
CC	GO:0030687	preribosome, large subunit precursor	12/7377	23/19717	0.1073	0.2611	0.1868	ZNF622/WDR37/EIF6/ZNF593/WDR74/MRTO4/LAS1L/NIP7/NOC2L/FTSJ3/RRP15/RRS1	12
CC	GO:0010494	cytoplasmic stress granule	30/7377	66/19717	0.1111	0.2697	0.1929	ZFP36/C9orf72/G3BP2/MOV10/GIGYF2/STAU1/HNRNPK/MBNL1/RBM4/HABP4/LARP4/DDX19B/EIF2S1/CAPRIN1/ATXN2/LSM14A/PUM2/DDX3X/ATXN2L/DDX1/GRB7/DYRK3/LARP4B/FMR1/EIF4E/CTSG/VCP/KPNB1/PABPC4L/TARDBP	30
CC	GO:0044291	cell-cell contact zone	32/7377	71/19717	0.1134	0.2734	0.1956	SLC8A1/FHOD1/ATP1A1/FLOT1/YWHAH/VCL/VAMP5/SLC9A1/CTNNA1/PAK1/ACTN1/RAP2C/SCN1B/AHNAK/RAP2B/FLOT2/FLCN/CTNNA3/PGM5/FXYD1/ATP1B1/RANGRF/FGFRL1/DSC2/CAV3/JAM3/HAMP/PKP2/FGF13/ATP1A2/GJA1/PCDH9	32
CC	GO:0000779	condensed chromosome, centromeric region	51/7377	118/19717	0.1134	0.2734	0.1956	DYNC1LI1/CEBPB/SPDL1/REC8/CENPW/NUP85/SEH1L/ZNF276/CENPE/NUP43/CENPT/CENPN/SKA2/SPAG5/MIS12/ZNF207/CENPC/CSNK1A1/CHAMP1/NCAPD3/BUB3/NDC80/BOD1L1/CBX3/ZWILCH/CKAP5/NUP107/DSN1/NDEL1/PHF6/NUF2/INCENP/ZW10/ERCC6L/CENPK/DYNLT3/PPP1CC/PMF1/CLASP2/SS18L1/KIF2C/SPC25/CENPA/NUDCD2/FBXO28/AURKA/DCTN6/MIS18BP1/DCTN5/BOD1/SKA3	51
CC	GO:0000109	nucleotide-excision repair complex	7/7377	12/19717	0.1164	0.2773	0.1984	RAD23B/ERCC4/XRCC1/ERCC1/CETN2/POLD1/ERCC8	7
CC	GO:0005845	mRNA cap binding complex	7/7377	12/19717	0.1164	0.2773	0.1984	ZFP36/AGO2/EIF4E3/EIF4E2/CYFIP1/FMR1/EIF4E	7
CC	GO:0032009	early phagosome	7/7377	12/19717	0.1164	0.2773	0.1984	APPL2/SYT11/RAB31/UNC13B/RAB5A/UNC93B1/APPL1	7
CC	GO:0097449	astrocyte projection	7/7377	12/19717	0.1164	0.2773	0.1984	EZR/PINK1/SLC7A11/EIF2S1/KCNK2/SYT4/APP	7
CC	GO:0045171	intercellular bridge	27/7377	59/19717	0.1173	0.2775	0.1985	KLHDC8B/NINL/PRKACB/MICAL1/FAM50B/SRA1/CEP131/SNRNP25/QSOX1/KRR1/KIF4A/USB1/GSTM3/CENPC/SETX/CEP55/EAF1/GSTM5/NTNG2/PRKACA/GSTM4/TRIM45/RAB35/AAMP/THAP11/CD34/RFXANK	27
CC	GO:0000242	pericentriolar material	11/7377	21/19717	0.1176	0.2775	0.1985	PCM1/CDK5RAP2/LCK/BBS4/HOOK3/CEP152/DYRK3/TUBG2/BBS9/WDR60/CEP85	11
CC	GO:0005697	telomerase holoenzyme complex	11/7377	21/19717	0.1176	0.2775	0.1985	LSM11/TEP1/SNRPB/NAT10/PTGES3/NHP2/HNRNPC/GAR1/GNL3L/TERT/NOP10	11
CC	GO:0031201	SNARE complex	22/7377	47/19717	0.1194	0.281	0.201	STX7/STX11/SEC22B/STXBP5/VAMP3/BLOC1S6/BET1/DOC2B/GOSR2/GOSR1/STX5/NAPA/STX16/VTI1A/NAPG/YKT6/STX18/STX12/VTI1B/STX8/SNX4/SNAP29	22
CC	GO:0030315	T-tubule	24/7377	52/19717	0.1236	0.2898	0.2073	SLC8A1/KCNJ5/EZR/ATP2B4/ATP1A1/SLC9A1/PPP3CB/RDX/SCN1B/AHNAK/RYR1/RTN2/SRI/FXYD1/GOT2/PRX/CAV3/CASQ1/TGFB3/CAPN3/CACNG6/CACNB3/ATP1A2/BIN1	24
CC	GO:0033655	host cell cytoplasm part	6/7377	10/19717	0.1262	0.2925	0.2093	GBP2/GBP4/RAB29/BICD1/LMAN1/GBP6	6
CC	GO:0035253	ciliary rootlet	6/7377	10/19717	0.1262	0.2925	0.2093	PSEN1/KIF5B/APP/NEK4/KLC3/RAB28	6
CC	GO:0072546	ER membrane protein complex	6/7377	10/19717	0.1262	0.2925	0.2093	EMC3/EMC2/EMC9/MMGT1/EMC1/EMC8	6
CC	GO:0098981	cholinergic synapse	6/7377	10/19717	0.1262	0.2925	0.2093	PLD1/DLGAP4/CHRNA10/CHRM2/CHRNB2/DLGAP3	6
CC	GO:0043204	perikaryon	57/7377	134/19717	0.1275	0.2946	0.2108	CRHBP/CCR2/RTN4R/C9orf72/KLHL24/SLC2A3/GIGYF2/KCNE3/SYAP1/SCN1B/CDK5/FCHSD1/ZPR1/AIF1/TRPM2/LRRK2/MCRS1/ROGDI/PAM/FUS/CHRNA10/DMWD/KCNAB1/OLFM1/CTSV/RTN4RL1/FZD5/CNR2/GOT2/KCNA2/NSMF/PPP1CA/AMIGO1/SLC8A2/FMR1/ASTN2/MAPK1/ENO2/MAP2K4/RTN4RL2/ITGA8/RUFY3/HTR5A/VIP/ATP7A/KNDC1/APP/GHRH/TOP1/AZIN2/EFNA2/SLC8A3/ENDOG/CACNA1F/NTSR1/SYNPO/ERCC8	57
CC	GO:0043034	costamere	10/7377	19/19717	0.1291	0.2958	0.2116	PLEC/VCL/AHNAK/SVIL/DMD/HOMER1/PGM5/KRT8/SMPX/DAG1	10
CC	GO:0098945	intrinsic component of presynaptic active zone membrane	10/7377	19/19717	0.1291	0.2958	0.2116	ATP2B4/SYT11/NPTN/FLOT2/P2RX1/NTNG2/CANX/P2RY4/CDH10/P2RY1	10
CC	GO:0031304	intrinsic component of mitochondrial inner membrane	21/7377	45/19717	0.1298	0.2958	0.2116	SCO2/CHCHD6/TIMM23B/SLC25A19/COX11/APOO/MCU/TIMM17A/ETFDH/MPC2/CHCHD10/AFG3L2/COX16/OXA1L/SFXN1/PET100/COA3/AGK/L2HGDH/APOOL/TMEM177	21
CC	GO:0031305	integral component of mitochondrial inner membrane	21/7377	45/19717	0.1298	0.2958	0.2116	SCO2/CHCHD6/TIMM23B/SLC25A19/COX11/APOO/MCU/TIMM17A/ETFDH/MPC2/CHCHD10/AFG3L2/COX16/OXA1L/SFXN1/PET100/COA3/AGK/L2HGDH/APOOL/TMEM177	21
CC	GO:0005640	nuclear outer membrane	13/7377	26/19717	0.1311	0.2958	0.2116	RETSAT/NUCB2/TMEM109/CCDC155/EMD/CLMN/SYNE2/CPTP/PSEN1/GUCY2D/NAV3/SNCA/SIGMAR1	13
CC	GO:0030867	rough endoplasmic reticulum membrane	13/7377	26/19717	0.1311	0.2958	0.2116	SSR4/RP9/ARL6IP1/SEC61B/TMEM97/PLOD1/PLOD2/DERL1/DERL2/SUCO/SEC61A2/UBA1/PI4KB	13
CC	GO:0030894	replisome	13/7377	26/19717	0.1311	0.2958	0.2116	RPA1/PRIM2/PURA/POLD4/DONSON/POLD2/BCAS2/PCNA/POLD1/POLA1/PRPF19/POLA2/TONSL	13
CC	GO:0033176	proton-transporting V-type ATPase complex	13/7377	26/19717	0.1311	0.2958	0.2116	ATP6V0D2/ATP6AP1/ATP6V1C1/ATP6V0C/TCIRG1/ATP6V1A/ATP6V1G3/ATP6V1B2/ATP6V1D/ATP6AP1L/ATP6V0E2/ATP6V1G2/ATP6V1B1	13
CC	GO:0014704	intercalated disc	23/7377	50/19717	0.134	0.3015	0.2157	SLC8A1/FHOD1/ATP1A1/YWHAH/VCL/VAMP5/SLC9A1/CTNNA1/PAK1/ACTN1/SCN1B/CTNNA3/PGM5/FXYD1/ATP1B1/RANGRF/DSC2/CAV3/HAMP/PKP2/FGF13/ATP1A2/GJA1	23
CC	GO:0098862	cluster of actin-based cell projections	63/7377	150/19717	0.1402	0.3146	0.225	EZR/PLS1/CLIC1/RALGDS/PLEC/RHOC/ACTN4/SLC22A5/SLC7A11/PVALB/LIMA1/MPP1/TWF2/CYBRD1/RDX/CD36/CAPZA2/MFSD10/ACTN1/IDO1/PAFAH1B1/PLB1/ATP8B1/SLC22A12/BBS2/MKKS/RGS19/TMC2/KPTN/ITLN1/MYO1C/MYL6/MYH9/MORN4/ADD3/ELMOD3/DAB1/PEX19/SLC46A1/SLC5A6/TPRN/DNM1L/ACTR3/SLC26A4/FLNB/SCIN/FLII/GNA13/SNX5/IFT20/SLC4A7/SCART1/ATP7A/HSP90AB1/EPS8L2/B4GALT1/CIB2/MYO15A/ANKS4B/ESPNL/TMC1/FCHSD2/KNCN	63
CC	GO:0008305	integrin complex	15/7377	31/19717	0.1409	0.3153	0.2255	ITGAM/LYN/ITGA5/ITGB7/ITGB5/ITGAD/ITGAL/TSPAN32/ITGA4/ITGA7/ITGA11/ITGAE/ITGA2/ITGA3/ITGA8	15
CC	GO:0005666	RNA polymerase III complex	9/7377	17/19717	0.1421	0.316	0.2261	POLR2L/POLR2H/POLR1C/POLR2F/POLR3E/POLR2K/POLR3F/POLR3GL/POLR3K	9
CC	GO:0031092	platelet alpha granule membrane	9/7377	17/19717	0.1421	0.316	0.2261	CYB5R1/PHACTR2/CD36/SPARC/SYTL4/LHFPL2/TMX3/SNCA/CD109	9
CC	GO:0097386	glial cell projection	12/7377	24/19717	0.144	0.3194	0.2285	FYN/EZR/PINK1/AKR1B1/SLC7A11/EIF2S1/KCNK2/ABCA7/FMR1/TMEM50A/SYT4/APP	12
CC	GO:0043198	dendritic shaft	17/7377	36/19717	0.1482	0.3278	0.2345	SLC8A1/RTN4R/PRKAR2B/FLNA/BAIAP2/CNIH3/ARHGEF2/SYNGAP1/LPAR1/CRIPT/PREX1/MAP1A/PSEN1/APP/LZTS1/NTSR1/ZMYND8	17
CC	GO:0016323	basolateral plasma membrane	89/7377	217/19717	0.1513	0.3333	0.2384	SLC40A1/NOD2/EZR/ATP2B4/ANXA1/SLC29A1/AQP9/ATP1A1/DISP1/SLC23A2/GM2A/FLOT1/CD44/SLC9A1/SLC2A9/PKD2/SLC7A7/ARRB1/HPGD/SLCO4C1/SLC7A6/P2RY6/CNNM2/SLC16A10/CLDN7/NUMB/LDLR/P2RY12/LRP1/CNNM4/ATP7B/MAP4K2/PDGFB/MYO1C/FLOT2/MLC1/PDZD11/SLC7A8/ATP1B1/CD1D/KCNQ1/SLC10A1/NKD2/SLC29A2/ITGA3/AP2A1/SLC41A1/OSCP1/EGFR/LIN7C/ORAI1/AQP3/CDH17/TFRC/CA11/LRRC7/ADAM9/SLC8A2/P2RY4/EPB41/MSN/SLC4A7/SLC4A1/ATP7A/CD34/SLC22A8/HSP90AB1/SLC14A1/TACSTD2/MEGF11/ABCC4/STXBP3/ANXA2/C5AR2/DAG1/B4GALT1/SLC9B2/ATP6V1B1/MET/SLC26A10/PIANP/SLC4A11/ATP12A/ERBB3/P2RY1/SLC12A6/BMPR2/SLCO1B1/BSND	89
CC	GO:0032155	cell division site part	28/7377	63/19717	0.1528	0.3333	0.2384	KLHDC8B/ICAM2/ARF6/RAB11A/RHOC/PSTPIP1/SPIRE1/LIMA1/RDX/PITPNM1/SVIL/RAB11FIP4/CENPC/MYH9/CEP55/TUBGCP3/HMCN1/MYLK/PPP1CC/TUBGCP5/PKN2/STAMBP/MASTL/MEN1/RHOA/SSH1/ZFYVE19/HTR3A	28
CC	GO:0032153	cell division site	30/7377	68/19717	0.1542	0.3333	0.2384	KLHDC8B/ICAM2/ARF6/RAB11A/RHOC/PSTPIP1/SPIRE1/RND3/LIMA1/RDX/PITPNM1/SVIL/RAB11FIP4/CENPC/MYH9/CEP55/TUBGCP3/RHOF/HMCN1/MYLK/PPP1CC/TUBGCP5/PKN2/STAMBP/MASTL/MEN1/RHOA/SSH1/ZFYVE19/HTR3A	30
CC	GO:0097733	photoreceptor cell cilium	48/7377	113/19717	0.1544	0.3333	0.2384	SPATA7/LYAR/GNB1/SHOC2/IFT57/DHRS3/KIFAP3/GNAQ/MYO5A/NAPEPLD/WDR19/PDE6G/OCRL/RPGR/IFT52/RPGRIP1/BBS4/NPHP4/MAK/OPN3/BBS7/LCA5/TBCC/FAM161A/CETN1/CETN2/MERTK/IFT20/GUCY2D/KIF17/PPEF2/NXNL1/PCDHB13/GRK4/INHA/PHLPP2/PCDHB15/TOPORS/CIB2/TULP1/CCDC66/PDC/CACNA1F/RAB27A/GNA11/RP1/OPN4/PTGS1	48
CC	GO:0044665	MLL1/2 complex	14/7377	29/19717	0.1545	0.3333	0.2384	E2F6/RUVBL2/RUVBL1/KAT8/MGA/INO80C/MCRS1/LAS1L/PHF20/PRPF31/TEX10/TAF4/WDR5/TAF7	14
CC	GO:0071339	MLL1 complex	14/7377	29/19717	0.1545	0.3333	0.2384	E2F6/RUVBL2/RUVBL1/KAT8/MGA/INO80C/MCRS1/LAS1L/PHF20/PRPF31/TEX10/TAF4/WDR5/TAF7	14
CC	GO:0090568	nuclear transcriptional repressor complex	14/7377	29/19717	0.1545	0.3333	0.2384	DR1/DDX20/ZBTB7A/MTA3/MBD3/RBBP7/RBBP4/SIRT1/ETV3/HDAC2/SUV39H1/SMARCA5/MTA2/TBX15	14
CC	GO:0000124	SAGA complex	8/7377	15/19717	0.1567	0.3333	0.2384	ENY2/ATXN7L3/TAF12/TAF6L/TAF9B/USP22/TADA3/SUPT20H	8
CC	GO:0005639	integral component of nuclear inner membrane	8/7377	15/19717	0.1567	0.3333	0.2384	SUN2/P2RX7/TMEM43/P2RX1/TMEM201/LEMD3/P2RX2/P2RX5	8
CC	GO:0031083	BLOC-1 complex	8/7377	15/19717	0.1567	0.3333	0.2384	BLOC1S2/DTNBP1/BLOC1S6/BLOC1S3/PI4K2A/BLOC1S1/BLOC1S4/STX12	8
CC	GO:0031229	intrinsic component of nuclear inner membrane	8/7377	15/19717	0.1567	0.3333	0.2384	SUN2/P2RX7/TMEM43/P2RX1/TMEM201/LEMD3/P2RX2/P2RX5	8
CC	GO:0031462	Cul2-RING ubiquitin ligase complex	8/7377	15/19717	0.1567	0.3333	0.2384	ZSWIM6/ZYG11B/GLMN/RNF7/COMMD1/CUL2/RBX1/ZYG11A	8
CC	GO:0035102	PRC1 complex	8/7377	15/19717	0.1567	0.3333	0.2384	PHC2/PCGF2/PCGF1/PCGF3/CBX7/CBX4/RING1/PHC1	8
CC	GO:0099059	integral component of presynaptic active zone membrane	8/7377	15/19717	0.1567	0.3333	0.2384	ATP2B4/SYT11/NPTN/P2RX1/CANX/P2RY4/CDH10/P2RY1	8
CC	GO:0031258	lamellipodium membrane	11/7377	22/19717	0.1585	0.3361	0.2404	VASP/CD44/DPP4/DOCK8/PLEK2/CSPG4/SYNE2/PLXND1/CFL1/KCNA2/NCKAP1	11
CC	GO:0031594	neuromuscular junction	33/7377	76/19717	0.167	0.3531	0.2526	TUBA1A/TBC1D24/SYNC/LAMB2/STXBP5/P2RX7/KCNC4/UNC13B/NRG1/CDK5/SYNGR2/FCHSD1/DLGAP4/MYH9/HDAC4/PRKACA/F2R/CAV3/LAMA2/PSEN1/SYNGR3/SYNGR4/SPOCK1/VAMP1/SNTA1/CHRNE/APP/CIB2/EFNA2/LRP4/SLC8A3/DLGAP3/FCHSD2	33
CC	GO:0005911	cell-cell junction	182/7377	459/19717	0.1701	0.3588	0.2567	MYADM/SLC8A1/CDC42EP4/VASP/PTPN6/MPP5/ANXA1/LYN/FHOD1/CSK/ITGA5/ATP1A1/RAP1B/AKR1B1/KLHL24/PDLIM1/PLEKHA7/FLNA/SMAD7/LSR/PACSIN2/CD2/ACTN4/FLOT1/YWHAH/F11R/CYTH1/VCL/VAMP5/P2RX7/SLC9A1/S100A11/PKD2/GAB1/TMOD3/DPP4/LCP2/CD53/CDK4/RDX/STARD10/CTNNA1/PAK1/RAPGEF2/PANX1/HEG1/PDLIM7/PRKCD/ACTN1/RAP2C/CLDN2/CORO1A/SCN1B/BAIAP2/AHNAK/DDX58/KIFC3/NCK1/VEGFA/CLDN7/CLDN12/SAPCD2/RAP2B/ARHGEF2/STRN/SYMPK/SPECC1L/CCND1/SH3BP1/NDRG1/ITK/EVPL/CDH5/EIF4G2/PCDH12/IGSF21/FLOT2/FLCN/CLIC4/KRIT1/MLC1/MYH9/TNKS1BP1/ZYX/CNN2/PDZD11/PDLIM5/CTNNA3/NPHP4/PGM5/CD99L2/ASH1L/FXYD1/MICALL2/ATP1B1/GJB4/CFL1/PVR/SIPA1L3/ADD3/RANGRF/MAP2K2/GRB2/TJAP1/ABCB4/ABCB11/YBX3/KRT8/FZD5/PARD6B/HMCN1/CD2AP/KCNA2/ACTR3/FGFRL1/CDSN/THEMIS/CLDN23/PPP1CA/VAV1/LIN7C/DSC2/PDZD2/PKN2/ADAM17/CAV3/ATP2A2/JAM3/AQP3/CDH17/FZD4/MPP7/MXRA8/TRIM29/LRRC7/FSCN1/HAMP/TCHP/FRMD4A/CDH10/PKP2/SKAP1/CLDN18/NHS/GJA8/TACSTD2/MTDH/PRKCZ/CLDN15/ANXA2/HPN/CADM3/RHOA/CDH3/APP/LIMS1/DAG1/CDHR3/B4GALT1/PDLIM4/GJD2/AMOTL1/SHROOM1/TRAF4/FGF13/ATP1A2/WAS/CD3E/UBA1/GJA1/GJA10/ADCYAP1R1/CDH26/PCDH9/GRHL2/LAT/CLDN6/PTPRM/PTPRJ/BMPR2/SYNPO/LAMA1	182
CC	GO:0005687	U4 snRNP	7/7377	13/19717	0.1734	0.3638	0.2602	SNRPB/SNRPD1/SNRPF/PRPF31/SNRPN/SNRPG/SNRPD2	7
CC	GO:0016580	Sin3 complex	7/7377	13/19717	0.1734	0.3638	0.2602	SIN3A/RBBP4/SIN3B/SUDS3/HDAC2/NCOR1/HEY2	7
CC	GO:0005721	pericentric heterochromatin	10/7377	20/19717	0.1749	0.3649	0.261	CBX5/CBX1/CENPC/NCAPD3/IKZF1/CBX3/INCENP/KDM4D/SNAI1/CENPA	10
CC	GO:0005868	cytoplasmic dynein complex	10/7377	20/19717	0.1749	0.3649	0.261	DYNC1LI1/DYNLL2/DYNC2LI1/DYNLRB1/DYNLRB2/DYNLT3/WDR60/SNX4/DYNC1LI2/TOPORS	10
CC	GO:0001650	fibrillar center	55/7377	132/19717	0.1778	0.3699	0.2646	JAZF1/EZR/CDCA7L/KLF6/SMAD7/FBLIM1/LIPA/UBE2N/FHIT/RPP38/CHD1/TXNRD1/IP6K1/CHCHD1/COIL/PSPC1/RSAD2/AGER/SPATA2/AFF4/INO80C/CD2BP2/NOLC1/SUMO1/FBL/AKNA/SNRPB2/UTP15/ORC6/GAR1/DSN1/DDX46/NFKBIE/POLR2F/LEO1/DCLRE1A/PEX14/SESN1/CRIPT/HERC4/IMP4/NUFIP1/TAF1C/TFCP2L1/FBLL1/MTDH/SMARCA5/CD3EAP/SAMD4A/TOP1/PAX5/MALT1/RRS1/SUPT20H/KDM4A	55
CC	GO:0005913	cell-cell adherens junction	49/7377	117/19717	0.1822	0.3782	0.2705	CDC42EP4/MPP5/ANXA1/LYN/PDLIM1/PLEKHA7/SMAD7/FLOT1/VCL/S100A11/TMOD3/RDX/CTNNA1/PDLIM7/ACTN1/BAIAP2/KIFC3/VEGFA/NDRG1/CDH5/EIF4G2/IGSF21/FLOT2/MYH9/TNKS1BP1/ZYX/PDLIM5/CTNNA3/PGM5/CD99L2/PVR/HMCN1/PPP1CA/DSC2/ATP2A2/CDH17/TRIM29/LRRC7/CDH10/PKP2/ANXA2/CDH3/DAG1/CDHR3/PDLIM4/GJA1/CDH26/PTPRM/BMPR2	49
CC	GO:0030880	RNA polymerase complex	47/7377	112/19717	0.1837	0.3801	0.2719	PAF1/ERCC4/GTF2E1/SETD5/TAF5L/PRIM2/CCNH/TAF11/TAF12/GTF2F2/POLR2L/TAF5/RPRD1B/POLR2H/GTF2H4/ZNFX1/RPRD2/ERCC1/GTF2F1/POLR1C/POLR2F/POLR2D/LEO1/TAF6L/TBPL1/POLR3E/KAT2A/GTF2A1/POLR2K/ERCC2/TAF9B/TAF4/RPAP2/POLA1/POLA2/TERT/POLRMT/POLR2J2/TBP/CD3EAP/POLR3F/CDC73/POLR3GL/TADA3/POLR2I/POLR3K/TAF7	47
CC	GO:1990391	DNA repair complex	19/7377	42/19717	0.1862	0.3843	0.2749	RAD23B/ERCC4/XRCC5/ATM/PMS2P5/XRCC4/MLH1/XRCC1/ERCC1/LIG4/CETN2/PHF21A/POLD1/PMS2P3/XRCC6/DCLRE1C/SWSAP1/ZSWIM7/ERCC8	19
CC	GO:0032421	stereocilium bundle	25/7377	57/19717	0.1914	0.3921	0.2805	RHOC/PVALB/MPP1/TWF2/RDX/IDO1/PAFAH1B1/ATP8B1/BBS2/MKKS/TMC2/KPTN/MYO1C/MORN4/ELMOD3/TPRN/IFT20/SLC4A7/EPS8L2/CIB2/MYO15A/ESPNL/TMC1/FCHSD2/KNCN	25
CC	GO:0030430	host cell cytoplasm	6/7377	11/19717	0.1926	0.3921	0.2805	GBP2/GBP4/RAB29/BICD1/LMAN1/GBP6	6
CC	GO:0031094	platelet dense tubular network	6/7377	11/19717	0.1926	0.3921	0.2805	ITPR1/EHD1/MRVI1/DMTN/F2R/ATP2A2	6
CC	GO:0031527	filopodium membrane	9/7377	18/19717	0.1935	0.3921	0.2805	VASP/ARF6/FZD9/DMD/HLA-G/SYNE2/ITGA3/MYO10/TBC1D10C	9
CC	GO:0032433	filopodium tip	9/7377	18/19717	0.1935	0.3921	0.2805	CIB1/UBE2K/MYO5A/CYFIP1/MORN4/AP2A1/FMR1/MYO10/EPHB1	9
CC	GO:0034719	SMN-Sm protein complex	9/7377	18/19717	0.1935	0.3921	0.2805	DDX20/SNRPB/GEMIN6/GEMIN7/SNRPD1/STRAP/SNRPF/SNRPG/SNRPD2	9
CC	GO:0070993	translation preinitiation complex	9/7377	18/19717	0.1935	0.3921	0.2805	EIF1/EIF1B/EIF3M/EIF3I/EIF2S1/EIF3G/EIF3B/EIF3J/EIF3L	9
CC	GO:0000803	sex chromosome	14/7377	30/19717	0.1941	0.3922	0.2805	BIRC2/SMC5/SMC6/PCGF2/PCGF3/UBE2A/SMCHD1/SIN3B/PBX4/SUMO1/RING1/DNMT3A/SMARCC1/UBE2B	14
CC	GO:0043197	dendritic spine	69/7377	169/19717	0.1996	0.4017	0.2874	NRGN/SLC8A1/CTTNBP2/APBA1/PRKAR2B/SIPA1L1/DNM3/SYT11/ALS2/ABHD17C/DOCK10/PTPRO/DNAJB1/ARRB1/ARF4/PTK2B/BAIAP2/ITSN1/PDE4B/OPHN1/DTNBP1/STRN/RAB8A/HOMER1/RAC1/CYFIP1/ARC/PTK2/SRI/SRGAP2/DNM1/DNM2/NEDD4/RGS14/FUS/SHISA9/PRKACA/MTMR2/SHANK1/LPAR1/CAMK2A/CANX/PPP1CC/PPP1CA/CRIPT/DVL1/SLC8A2/LAMA2/FMR1/ITGA8/OPRD1/KCNA4/PSMC2/RHOA/APP/PDLIM4/ASAP1/ATP1A2/SLC8A3/CD3E/SHISA8/LZTS1/SHANK3/TENM2/GRIA2/NTSR1/ZMYND8/NTRK2/SYNPO	69
CC	GO:0044441	ciliary part	182/7377	462/19717	0.1998	0.4017	0.2874	ARMC9/SPATA7/PKD2L1/EZR/ATP2B4/PRKAR2B/ATG7/RILPL1/BBS5/TCTN1/LYAR/GNB1/ATG14/SQSTM1/TTC8/FOPNL/DEFB1/EVC/IFT172/ODF2/SHOC2/PRKACB/PKD2/IFT57/AK2/DHRS3/CNTRL/KIF3B/DAAM1/TULP3/KIFAP3/GNAQ/CEP164/MAP4/PCM1/MYO5A/DYNLL2/SPA17/ARL13B/WDR11/CEP131/CBY1/NAPEPLD/IFT80/C5orf30/CLTB/RP2/AK8/WDR19/INTU/TAS2R4/EHD1/PDE6G/BBS2/RAB8A/MKKS/IFT46/CCDC88A/IQCE/KIF2A/OCRL/RPGR/DNAL1/CYLD/GSTM3/IFT52/RPGRIP1/WDR66/B9D1/BBS4/CSNK1A1/TCTN2/NPHP4/MAK/DISC1/C8orf37/HSPB11/PMFBP1/WDPCP/DNAI2/DNAH17/MLF1/CCDC120/CCR6/PRKACA/DYNC2LI1/OPN3/RSPH9/BBS7/TBC1D7/HYAL3/MKS1/TTLL3/CCDC151/DYNLRB1/PGK2/CCDC65/ODF1/DYNLRB2/LCA5/TBCC/FAM161A/CETN1/CETN2/RSPH6A/MXRA8/TUBB4A/BBS9/TMEM231/TACR1/PSEN1/CEP19/MERTK/IFT20/GUCY2D/CEP83/DNAI1/LYZL6/KIF17/MOK/WDR60/TMEM80/PPEF2/NXNL1/PCDHB13/UNC119B/MAATS1/KIF5B/GRK4/PKHD1/EHD3/IFT22/GPR161/INHA/PHLPP2/WDR35/JADE1/PCDHB15/TRAF3IP1/SNAP29/DNAH10/TCTN3/DZIP1L/TOPORS/APP/TTBK2/SLC9B2/CIB2/TMEM107/CEP78/IFT74/NEK4/TULP1/CCDC63/EFHC1/NEK8/SPAG17/CCDC66/KLC3/PDC/SMO/CACNA1F/DNAH8/SHANK3/TTLL6/TTC30B/RAB27A/DNAH2/IFT81/GNA11/RP1/PTCH1/POC1B/C2CD3/GAS8/OPN4/PTGS1/WRAP73/TACR2/SPATA6/RAB28/KNCN	182
CC	GO:0005747	mitochondrial respiratory chain complex I	22/7377	50/19717	0.2058	0.4106	0.2937	NDUFA8/NDUFC1/NDUFB11/NDUFS3/NDUFA3/NDUFA11/NDUFA4/NDUFA1/WDR93/NDUFA10/NDUFB1/NDUFB5/NDUFS1/NDUFB8/NDUFB6/NDUFB3/NDUFS7/NDUFV2/ND4/NDUFB2/NDUFS2/NDUFA7	22
CC	GO:0030964	NADH dehydrogenase complex	22/7377	50/19717	0.2058	0.4106	0.2937	NDUFA8/NDUFC1/NDUFB11/NDUFS3/NDUFA3/NDUFA11/NDUFA4/NDUFA1/WDR93/NDUFA10/NDUFB1/NDUFB5/NDUFS1/NDUFB8/NDUFB6/NDUFB3/NDUFS7/NDUFV2/ND4/NDUFB2/NDUFS2/NDUFA7	22
CC	GO:0045271	respiratory chain complex I	22/7377	50/19717	0.2058	0.4106	0.2937	NDUFA8/NDUFC1/NDUFB11/NDUFS3/NDUFA3/NDUFA11/NDUFA4/NDUFA1/WDR93/NDUFA10/NDUFB1/NDUFB5/NDUFS1/NDUFB8/NDUFB6/NDUFB3/NDUFS7/NDUFV2/ND4/NDUFB2/NDUFS2/NDUFA7	22
CC	GO:0000428	DNA-directed RNA polymerase complex	45/7377	108/19717	0.2065	0.4109	0.2939	PAF1/ERCC4/GTF2E1/SETD5/TAF5L/PRIM2/CCNH/TAF11/TAF12/GTF2F2/POLR2L/TAF5/RPRD1B/POLR2H/GTF2H4/RPRD2/ERCC1/GTF2F1/POLR1C/POLR2F/POLR2D/LEO1/TAF6L/TBPL1/POLR3E/KAT2A/GTF2A1/POLR2K/ERCC2/TAF9B/TAF4/RPAP2/POLA1/POLA2/POLRMT/POLR2J2/TBP/CD3EAP/POLR3F/CDC73/POLR3GL/TADA3/POLR2I/POLR3K/TAF7	45
CC	GO:0044295	axonal growth cone	13/7377	28/19717	0.2129	0.4225	0.3022	RTN4R/C9orf72/TRAK2/LRP1/CYFIP1/L1CAM/OLFM1/KIF5B/TRAK1/HSP90AB1/BOC/PTCH1/TRPV2	13
CC	GO:0005746	mitochondrial respiratory chain	37/7377	88/19717	0.214	0.4232	0.3028	C15orf48/UQCRC2/NDUFA8/NDUFC1/NDUFB11/NDUFS3/NDUFA3/NDUFA11/UQCR10/COX7A2L/NDUFA4/COX4I2/NDUFA1/WDR93/OXA1L/COX15/NDUFA10/NDUFB1/NDUFB5/UQCRQ/NDUFS1/COA3/NDUFB8/SURF1/NDUFB6/NDUFB3/SDHA/NDUFS7/NDUFV2/ND4/SDHD/UQCRB/NDUFB2/NNT/NDUFS2/NDUFA7/COX7B	37
CC	GO:0042575	DNA polymerase complex	8/7377	16/19717	0.2149	0.4232	0.3028	MAD2L2/CHRAC1/POLD4/POLD2/POLG/POLD1/TERT/POLE4	8
CC	GO:0044453	nuclear membrane part	8/7377	16/19717	0.2149	0.4232	0.3028	SUN2/P2RX7/TMEM43/P2RX1/TMEM201/LEMD3/P2RX2/P2RX5	8
CC	GO:0016591	RNA polymerase II, holoenzyme	35/7377	83/19717	0.2157	0.4238	0.3031	PAF1/ERCC4/GTF2E1/SETD5/TAF5L/CCNH/TAF11/TAF12/GTF2F2/POLR2L/TAF5/RPRD1B/POLR2H/GTF2H4/RPRD2/ERCC1/GTF2F1/POLR2F/POLR2D/LEO1/TAF6L/TBPL1/KAT2A/GTF2A1/POLR2K/ERCC2/TAF9B/TAF4/RPAP2/POLR2J2/TBP/CDC73/TADA3/POLR2I/TAF7	35
CC	GO:0000792	heterochromatin	33/7377	78/19717	0.2173	0.4259	0.3046	CBX5/UHRF1/CBX6/PHC2/MORC2/PCGF2/CBX1/MBD3/SIRT7/HMGA1/PML/UBE2A/SMARCAD1/SIRT1/UHRF2/CENPC/SUMO1/TNKS1BP1/NCAPD3/IKZF1/SUV39H1/CBX3/TOP2B/INCENP/RING1/KDM4D/RNF20/DNMT3A/SNAI1/CENPA/WDR76/UBA1/UBE2B	33
CC	GO:0000930	gamma-tubulin complex	10/7377	21/19717	0.227	0.4437	0.3174	BLOC1S2/PDE4B/CDK5RAP2/TUBGCP3/CKAP5/TUBG2/BRCA1/TUBGCP5/TOPORS/UXT	10
CC	GO:0000780	condensed nuclear chromosome, centromeric region	12/7377	26/19717	0.2339	0.4549	0.3254	REC8/MIS12/CENPC/NDC80/DSN1/NUF2/CENPK/PMF1/SS18L1/CENPA/AURKA/MIS18BP1	12
CC	GO:0036452	ESCRT complex	12/7377	26/19717	0.2339	0.4549	0.3254	STAM/VPS37B/CHMP4B/VPS37C/CHMP2A/TSG101/UBAP1/HGS/CHMP1A/VPS25/UBAP1L/CHMP1B	12
CC	GO:0044309	neuron spine	69/7377	171/19717	0.2356	0.4558	0.326	NRGN/SLC8A1/CTTNBP2/APBA1/PRKAR2B/SIPA1L1/DNM3/SYT11/ALS2/ABHD17C/DOCK10/PTPRO/DNAJB1/ARRB1/ARF4/PTK2B/BAIAP2/ITSN1/PDE4B/OPHN1/DTNBP1/STRN/RAB8A/HOMER1/RAC1/CYFIP1/ARC/PTK2/SRI/SRGAP2/DNM1/DNM2/NEDD4/RGS14/FUS/SHISA9/PRKACA/MTMR2/SHANK1/LPAR1/CAMK2A/CANX/PPP1CC/PPP1CA/CRIPT/DVL1/SLC8A2/LAMA2/FMR1/ITGA8/OPRD1/KCNA4/PSMC2/RHOA/APP/PDLIM4/ASAP1/ATP1A2/SLC8A3/CD3E/SHISA8/LZTS1/SHANK3/TENM2/GRIA2/NTSR1/ZMYND8/NTRK2/SYNPO	69
CC	GO:0030140	trans-Golgi network transport vesicle	14/7377	31/19717	0.2378	0.4558	0.326	NRGN/AFTPH/GOPC/IGF2R/TMED10/CLTB/FURIN/RAB8A/AP1G2/CLTCL1/AP2A1/RAB8B/AP1G1/ATP7A	14
CC	GO:0000346	transcription export complex	7/7377	14/19717	0.2397	0.4558	0.326	NXF1/CHTOP/ALYREF/SARNP/THOC2/THOC5/THOC6	7
CC	GO:0030688	preribosome, small subunit precursor	7/7377	14/19717	0.2397	0.4558	0.326	TSR1/FTSJ3/LTV1/RIOK2/RIOK3/NOC4L/FAM207A	7
CC	GO:0031588	nucleotide-activated protein kinase complex	7/7377	14/19717	0.2397	0.4558	0.326	SIK1/SIK2/PRKAG2/PRKAA1/PRKAG1/SESN2/PRKAB1	7
CC	GO:0034362	low-density lipoprotein particle	7/7377	14/19717	0.2397	0.4558	0.326	LSR/PLA2G7/APOE/APOO/LDLR/APOBR/APOA1	7
CC	GO:0034518	RNA cap binding complex	7/7377	14/19717	0.2397	0.4558	0.326	ZFP36/AGO2/EIF4E3/EIF4E2/CYFIP1/FMR1/EIF4E	7
CC	GO:0042588	zymogen granule	7/7377	14/19717	0.2397	0.4558	0.326	GNAI3/STXBP2/SCAMP1/TMED10/DMBT1/CLCA1/RAB3D	7
CC	GO:0061702	inflammasome complex	7/7377	14/19717	0.2397	0.4558	0.326	NLRP3/AIM2/CASP5/NLRP9/CASP1/CASP4/NLRP1	7
CC	GO:0055029	nuclear DNA-directed RNA polymerase complex	44/7377	107/19717	0.2424	0.4599	0.329	PAF1/ERCC4/GTF2E1/SETD5/TAF5L/PRIM2/CCNH/TAF11/TAF12/GTF2F2/POLR2L/TAF5/RPRD1B/POLR2H/GTF2H4/RPRD2/ERCC1/GTF2F1/POLR1C/POLR2F/POLR2D/LEO1/TAF6L/TBPL1/POLR3E/KAT2A/GTF2A1/POLR2K/ERCC2/TAF9B/TAF4/RPAP2/POLA1/POLA2/POLR2J2/TBP/CD3EAP/POLR3F/CDC73/POLR3GL/TADA3/POLR2I/POLR3K/TAF7	44
CC	GO:0000159	protein phosphatase type 2A complex	9/7377	19/19717	0.2515	0.4736	0.3388	IER5/PPP2CA/PPP2R3A/PPP2R5C/PPP2R2D/PPP2R2B/PPP2R1B/PPP2R5B/PPP2R2C	9
CC	GO:0016010	dystrophin-associated glycoprotein complex	9/7377	19/19717	0.2515	0.4736	0.3388	DMD/SNTB1/PGM5/SSPN/KRT8/CAV3/SNTB2/SNTA1/DAG1	9
CC	GO:0090665	glycoprotein complex	9/7377	19/19717	0.2515	0.4736	0.3388	DMD/SNTB1/PGM5/SSPN/KRT8/CAV3/SNTB2/SNTA1/DAG1	9
CC	GO:0000313	organellar ribosome	36/7377	87/19717	0.2547	0.4773	0.3414	MRPS6/C12orf65/MRPL35/MRPL45/CHCHD1/MRPL40/MRPS30/MRPL34/MRPS16/MRPS14/MRPL54/MRPL44/MRPL33/MRPL51/MRPL49/MRPL3/MRPL42/DAP3/MRPS34/MRPL4/MRPS33/MRPL20/MRPL46/MRPS18B/MRPL24/MRPL36/MRPS15/MRPL48/MRPL41/MRPL2/MPV17L2/MRPS2/MRPS9/NDUFA7/MRPL30/MRPS17	36
CC	GO:0005761	mitochondrial ribosome	36/7377	87/19717	0.2547	0.4773	0.3414	MRPS6/C12orf65/MRPL35/MRPL45/CHCHD1/MRPL40/MRPS30/MRPL34/MRPS16/MRPS14/MRPL54/MRPL44/MRPL33/MRPL51/MRPL49/MRPL3/MRPL42/DAP3/MRPS34/MRPL4/MRPS33/MRPL20/MRPL46/MRPS18B/MRPL24/MRPL36/MRPS15/MRPL48/MRPL41/MRPL2/MPV17L2/MRPS2/MRPS9/NDUFA7/MRPL30/MRPS17	36
CC	GO:0043601	nuclear replisome	11/7377	24/19717	0.2575	0.4808	0.3439	RPA1/PRIM2/PURA/POLD4/POLD2/BCAS2/POLD1/POLA1/PRPF19/POLA2/TONSL	11
CC	GO:0098685	Schaffer collateral - CA1 synapse	34/7377	82/19717	0.2578	0.4808	0.3439	FYN/APBA1/GABBR1/SYT11/STAT3/RAB11A/STXBP5/ACTB/ITPR1/BAIAP2/FBXL20/ADRB1/ABR/CDK5/DTNBP1/NPTN/DCC/ADCY1/BCR/SH3GL1/ADORA2B/NTNG2/GRASP/SHANK1/CAMK2A/IQSEC2/DVL1/INA/PRKCZ/RNF216/GSG1L/WNT7A/GHRL/SYNPO	34
CC	GO:0001917	photoreceptor inner segment	21/7377	49/19717	0.2587	0.4814	0.3444	ASRGL1/DNM3/DRAM2/GNB1/SHOC2/RDH12/BBS4/DNM1/MAK/C8orf37/DNM2/FAM161A/ENO2/PPEF2/INHA/PHLPP2/CIB2/TULP1/CCDC66/PDC/RP1	21
CC	GO:0032994	protein-lipid complex	17/7377	39/19717	0.2612	0.4848	0.3468	PCYOX1/LSR/APOC1/PLA2G7/CETP/APOE/HDLBP/APOO/LDLR/APOBR/CLU/APOL1/APOA5/LCAT/PEX3/APOA1/BIN1	17
CC	GO:0000812	Swr1 complex	6/7377	12/19717	0.2688	0.4906	0.351	ANP32E/RUVBL2/RUVBL1/BRD8/KAT5/ING3	6
CC	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex	6/7377	12/19717	0.2688	0.4906	0.351	CCNH/CDK9/BCCIP/CCNK/RB1/CCNT1	6
CC	GO:0030008	TRAPP complex	6/7377	12/19717	0.2688	0.4906	0.351	TRAPPC5/TRAPPC9/TRAPPC2L/TRAPPC3/TRAPPC8/TRAPPC11	6
CC	GO:0030897	HOPS complex	6/7377	12/19717	0.2688	0.4906	0.351	VPS41/VPS33A/HOOK2/HOOK3/VPS18/VPS16	6
CC	GO:0030914	STAGA complex	6/7377	12/19717	0.2688	0.4906	0.351	SUPT7L/TAF5L/TAF12/TAF6L/KAT2A/TADA3	6
CC	GO:0042555	MCM complex	6/7377	12/19717	0.2688	0.4906	0.351	MCM6/MCM2/MCM5/MCM8/MCMBP/TONSL	6
CC	GO:0097504	Gemini of coiled bodies	6/7377	12/19717	0.2688	0.4906	0.351	DDX20/HABP4/ZPR1/GEMIN6/GEMIN7/NPAT	6
CC	GO:0005791	rough endoplasmic reticulum	35/7377	85/19717	0.2704	0.4925	0.3523	CKAP4/SLC7A11/SSR4/SEC62/ARSB/RP9/ARL6IP1/SEC61B/LRPAP1/STAU1/TMCC1/BAIAP2/NCF1/FKRP/TMEM97/PLOD1/RPS21/RPN2/SCGB1A1/PLOD2/DERL1/RANGRF/CYBB/CANX/DERL2/SUCO/PSEN1/HTR5A/APP/SNCA/SEC61A2/UBA1/ADCYAP1R1/TRAM1/PI4KB	35
CC	GO:0033267	axon part	149/7377	382/19717	0.2749	0.4994	0.3572	CRHBP/RTN4R/DPYSL3/BLVRB/TBC1D24/PINK1/TSC1/SOD1/KCNAB2/SYT11/BLOC1S2/C9orf72/LRIG2/TIMP2/KLC1/ANKRD9/MBP/ZC3H14/CIB1/ORAI2/ALS2/UCHL1/KCNC4/HNRNPR/CBX6/PTPRO/MICAL1/KCNA3/TSHZ3/NDRG2/ACTB/KIF3B/TWF2/UNC13B/HIF1A/HSPB1/PTK2B/MYO5A/SYAP1/SYNJ1/SCN1B/STMN3/ITGA4/TPRG1L/ITSN1/AP3M2/USP9X/CDK5/TRAK2/PAFAH1B1/TUBB3/CTSZ/OPHN1/ZPR1/DTNBP1/MAP3K12/BLOC1S6/KIF4A/LRP1/BASP1/SPTBN1/LRRK2/CYFIP1/SRI/SETX/DICER1/GDPD5/TOR1A/ARL8A/DNM1/POLG/NRP1/DISC1/DNM2/BLOC1S3/L1CAM/ERMN/CCDC120/ROR1/KIF20B/DCTN2/RAB5A/KCNAB1/ITGA2/NDEL1/OLFM1/PTPRN2/KCNK2/ITGA3/KCNA2/CHRM2/BLOC1S1/RASGRF1/BLOC1S4/CDK5R2/UNC5C/AP3B1/AMIGO1/PREX1/TUBB4A/LRRC7/FSCN1/DVL1/MAP1A/PSEN1/FMR1/RAB3A/YWHAE/KATNB1/EXOC4/CAD/KIF1B/RUFY3/LMTK2/SPOCK1/AP3M1/SCN8A/KIF5B/TRAK1/OPRD1/CABP4/HSP90AB1/ACAP3/PRKCZ/KIF1C/TRPV4/AURKA/BRSK1/APP/GHRH/DAG1/SNCA/SIGMAR1/SSH1/TULP1/FGF13/BOC/UCN3/TENM2/MGARP/BIN1/PTCH1/PCDH9/TRPV2/NTSR1/ARL8B/NTRK2/TRIM46/NPTXR	149
CC	GO:0032420	stereocilium	22/7377	52/19717	0.2763	0.5008	0.3582	RHOC/PVALB/MPP1/TWF2/RDX/PAFAH1B1/ATP8B1/BBS2/TMC2/KPTN/MYO1C/MORN4/ELMOD3/TPRN/IFT20/SLC4A7/EPS8L2/CIB2/MYO15A/ESPNL/TMC1/FCHSD2	22
CC	GO:0016282	eukaryotic 43S preinitiation complex	8/7377	17/19717	0.2796	0.5033	0.3601	EIF1/EIF1B/EIF3M/EIF3I/EIF3G/EIF3B/EIF3J/EIF3L	8
CC	GO:0035859	Seh1-associated complex	8/7377	17/19717	0.2796	0.5033	0.3601	WDR24/SEH1L/NPRL3/RRAGA/SESN1/NPRL2/DEPDC5/SESN2	8
CC	GO:0097440	apical dendrite	8/7377	17/19717	0.2796	0.5033	0.3601	FLNA/PTK2B/ITSN1/CLU/PPARGC1A/CPEB3/YKT6/NSMF	8
CC	GO:0005685	U1 snRNP	16/7377	37/19717	0.2836	0.5092	0.3643	SNRPB/LUC7L/SNRPD1/SNRPA/SNRPC/SNRPB2/PRPF40B/PRPF40A/LUC7L2/SNRPF/WEE2-AS1/PRPF39/SNRPN/LUC7L3/SNRPG/SNRPD2	16
CC	GO:0098793	presynapse	190/7377	491/19717	0.2912	0.5217	0.3732	CRHBP/SLC40A1/RTN4R/CTTNBP2/APBA1/ATP2B4/PPFIBP2/STX7/SLC29A1/BLVRB/ARF6/TBC1D24/GABBR1/STX11/DNM3/KCNAB2/SYT11/POTEKP/FCHO2/FLOT1/DENND1A/SEC22B/STXBP5/P2RX7/CTBP2/LAMP1/KCNC4/EPHB2/WDR7/HNRNPR/FXYD6/MICAL1/KCNA3/SLC2A8/ACTB/STXBP1/SYPL1/CLN8/UNC13B/SGTA/WFS1/SYAP1/SYNJ1/RABAC1/BAIAP2/FBXO45/FBXL20/TPRG1L/ITSN1/CDK5/VAMP3/PDE4B/CLCN3/SCAMP1/SYNGR2/OPHN1/TMEM230/C16orf70/CLTB/DTNBP1/CLN3/SEMA4C/BLOC1S6/SYNJ2/RAB8A/DOC2B/NPTN/RAB33B/LRRK2/CYFIP1/IGSF21/FLOT2/SYT6/PSEN2/SRI/DNAJC6/ATG9A/ROGDI/PDZD11/TOR1A/SPHK1/SH3GL1/DNM1/P2RX1/POLG/DISC1/SLC6A5/VPS18/NAPA/DNM2/PPFIA4/ROR1/NTNG2/PI4K2A/RAB5A/KIAA1107/ITGA2/NDEL1/STX16/MTMR2/VDAC2/VTI1A/SLC29A2/PTPRN2/KCNK2/SLC17A5/CANX/KCNA2/CHRM2/DNM1L/VDAC1/CHRNA4/PPP1CC/PPP1CA/RAB8B/C1QBP/LIN7C/ICA1/C1QL1/PLD2/DVL1/PSEN1/SYNGR3/FMR1/SYNGR4/RAB3A/CHRNB2/P2RY4/RAB35/STX12/PPFIA3/SYPL2/VTI1B/SYT9/CDH10/CAD/FOSL1/NUFIP1/ZNRF1/PNISR/SYT1/OPRD1/CABP4/RAB3B/SPTBN2/SYT2/YWHAG/VAMP1/STXBP3/DOC2A/SNAP29/SYT4/GPC4/CADPS2/SNCAIP/SYT5/SCAMP5/CADM3/CHAT/PICK1/BRSK1/APP/GHRH/RAB3D/SNCA/SLC9B2/ATP6V1B1/APH1A/TULP1/RIMS2/WNT7A/PICALM/CYP46A1/NLGN2/SYN3/KIAA1109/UCN3/KCTD16/RAB26/BIN1/P2RY1/HTR3A/AMPH/CNTN1/NTSR1/ZNRF2/NTRK2/DMXL2/LGI3/SV2B	190
CC	GO:0044449	contractile fiber part	87/7377	221/19717	0.2956	0.5283	0.378	SLC8A1/TRIM32/ATP2B4/PDLIM1/SYNC/PLEC/FLNA/MTMR12/FHL3/ACTN4/SQSTM1/KLHL41/TPM3/VCL/TMOD3/KAT2B/MYL6B/PPP3CB/PARVB/PAK1/HSPB1/CFL2/PDLIM7/ACTN1/AHNAK/RYR1/HABP4/ACTC1/TNNI2/PDE4B/SVIL/ENO1/IDO1/MYBPC3/ALDOA/NEXN/ACTA2/DMD/HOMER1/SPTBN1/DNAJB6/TIMP4/PSEN2/SRI/ARF1/SYNE2/TPM4/PDLIM5/GLRX3/PGM5/TPM1/HDAC4/TNNC2/OBSCN/KLHL40/KRT8/SMPX/CORO1C/STUB1/MYL5/FLNB/MYOZ1/LMOD3/CAV3/MYZAP/FHL2/MYOM2/CASQ1/SLC4A1/CAPN3/CASQ2/HRC/SCN8A/LRRC39/SYNPO2L/MYH2/MMP2/CSRP1/DAG1/PDLIM4/NBR1/MYH3/ACTA1/BIN1/TNNT1/MYOZ3/SYNPO	87
CC	GO:0005903	brush border	40/7377	99/19717	0.3021	0.5305	0.3795	EZR/PLS1/CLIC1/RALGDS/PLEC/ACTN4/SLC22A5/SLC7A11/LIMA1/CYBRD1/CD36/CAPZA2/MFSD10/ACTN1/PLB1/ATP8B1/SLC22A12/RGS19/ITLN1/MYO1C/MYL6/MYH9/ADD3/DAB1/PEX19/SLC46A1/SLC5A6/DNM1L/ACTR3/SLC26A4/FLNB/SCIN/FLII/GNA13/SNX5/SCART1/ATP7A/HSP90AB1/B4GALT1/ANKS4B	40
CC	GO:0000813	ESCRT I complex	5/7377	10/19717	0.3037	0.5305	0.3795	VPS37B/VPS37C/TSG101/UBAP1/UBAP1L	5
CC	GO:0016461	unconventional myosin complex	5/7377	10/19717	0.3037	0.5305	0.3795	MYL6B/MYO5A/DYNLL2/MYO1C/MYL6	5
CC	GO:0030681	multimeric ribonuclease P complex	5/7377	10/19717	0.3037	0.5305	0.3795	RPP38/RPP25/RPP14/RPP40/POP7	5
CC	GO:0031080	nuclear pore outer ring	5/7377	10/19717	0.3037	0.5305	0.3795	NUP160/NUP85/SEH1L/NUP43/NUP107	5
CC	GO:0031414	N-terminal protein acetyltransferase complex	5/7377	10/19717	0.3037	0.5305	0.3795	NAA20/NAA10/NAA38/NAA16/NAA15	5
CC	GO:0036513	Derlin-1 retrotranslocation complex	5/7377	10/19717	0.3037	0.5305	0.3795	RNF139/DERL1/RNF185/RNF5/VCP	5
CC	GO:0070938	contractile ring	5/7377	10/19717	0.3037	0.5305	0.3795	ALKBH4/MYH9/KIF20B/DAG1/PRC1	5
CC	GO:0072588	box H/ACA RNP complex	5/7377	10/19717	0.3037	0.5305	0.3795	NOLC1/NHP2/GAR1/SNORA74A/NOP10	5
CC	GO:0097470	ribbon synapse	5/7377	10/19717	0.3037	0.5305	0.3795	CTBP2/UNC13B/NPHP4/DNM1/ATP2A2	5
CC	GO:0005720	nuclear heterochromatin	15/7377	35/19717	0.308	0.531	0.3798	CBX5/UHRF1/PCGF2/CBX1/SIRT7/SIRT1/UHRF2/CENPC/TNKS1BP1/NCAPD3/IKZF1/CBX3/RING1/DNMT3A/CENPA	15
CC	GO:0008023	transcription elongation factor complex	24/7377	58/19717	0.3095	0.531	0.3798	ELL2/PAF1/ELP4/ERCC6/SETD5/AFF4/ELL3/CDK9/EAF1/ELP3/CCNK/SUPT4H1/SSRP1/LEO1/ELP2/NELFCD/NUFIP1/RB1/SUPT16H/CCNT1/CDC73/AFF3/ICE1/TONSL	24
CC	GO:0035861	site of double-strand break	24/7377	58/19717	0.3095	0.531	0.3798	MAD2L2/HUS1B/ACTR2/ZBTB7A/SMC5/RNF138/SMC6/SETMAR/ARPC1A/SAMHD1/SMCHD1/SMARCAD1/POLH/PARP3/RFWD3/TIMELESS/KDM4D/ACTR3/ARPC4/PRPF19/ARPC2/VCP/APLF/WAS	24
CC	GO:0034451	centriolar satellite	13/7377	30/19717	0.311	0.531	0.3798	BBS5/FLOT1/FOPNL/PCM1/CEP131/KIAA0753/SPAG5/BBS4/HOOK3/BBS9/CCDC13/CCDC66/C2CD3	13
CC	GO:0048787	presynaptic active zone membrane	13/7377	30/19717	0.311	0.531	0.3798	APBA1/ATP2B4/STX11/SYT11/STXBP1/NPTN/FLOT2/P2RX1/NTNG2/CANX/P2RY4/CDH10/P2RY1	13
CC	GO:0005665	RNA polymerase II, core complex	7/7377	15/19717	0.3122	0.531	0.3798	POLR2L/POLR2H/POLR2F/POLR2D/POLR2K/POLR2J2/POLR2I	7
CC	GO:0012510	trans-Golgi network transport vesicle membrane	7/7377	15/19717	0.3122	0.531	0.3798	NRGN/AFTPH/CLTB/AP1G2/CLTCL1/AP2A1/AP1G1	7
CC	GO:0016581	NuRD complex	7/7377	15/19717	0.3122	0.531	0.3798	ZBTB7A/MTA3/MBD3/RBBP7/RBBP4/HDAC2/MTA2	7
CC	GO:0031616	spindle pole centrosome	7/7377	15/19717	0.3122	0.531	0.3798	UBXN2B/NPM1/EMD/NSFL1C/DLGAP5/MISP/AURKA	7
CC	GO:0033290	eukaryotic 48S preinitiation complex	7/7377	15/19717	0.3122	0.531	0.3798	EIF3M/EIF3I/EIF2S1/EIF3G/EIF3B/EIF3J/EIF3L	7
CC	GO:0090545	CHD-type complex	7/7377	15/19717	0.3122	0.531	0.3798	ZBTB7A/MTA3/MBD3/RBBP7/RBBP4/HDAC2/MTA2	7
CC	GO:0005849	mRNA cleavage factor complex	9/7377	20/19717	0.3142	0.531	0.3798	PCF11/CPSF3/CLP1/CSNK1A1/FIP1L1/CSTF1/CPSF2/CPSF1/CPSF7	9
CC	GO:0030904	retromer complex	9/7377	20/19717	0.3142	0.531	0.3798	SNX1/DENND5A/TBC1D5/DENND4C/SNX27/SNX6/VPS29/SNX5/VPS26B	9
CC	GO:0034361	very-low-density lipoprotein particle	9/7377	20/19717	0.3142	0.531	0.3798	PCYOX1/LSR/APOC1/APOE/APOO/APOBR/APOL1/APOA5/APOA1	9
CC	GO:0034385	triglyceride-rich plasma lipoprotein particle	9/7377	20/19717	0.3142	0.531	0.3798	PCYOX1/LSR/APOC1/APOE/APOO/APOBR/APOL1/APOA5/APOA1	9
CC	GO:0150034	distal axon	111/7377	285/19717	0.3153	0.5317	0.3804	CRHBP/RTN4R/DPYSL3/BLVRB/TBC1D24/PINK1/TSC1/KCNAB2/SYT11/C9orf72/LRIG2/TIMP2/KLC1/CIB1/ORAI2/ALS2/KCNC4/HNRNPR/CBX6/PTPRO/MICAL1/KCNA3/TSHZ3/NDRG2/ACTB/TWF2/UNC13B/PTK2B/MYO5A/SYAP1/SYNJ1/STMN3/ITGA4/TPRG1L/ITSN1/USP9X/CDK5/TRAK2/PAFAH1B1/TUBB3/CTSZ/OPHN1/ZPR1/DTNBP1/MAP3K12/LRP1/BASP1/LRRK2/CYFIP1/SRI/SETX/DICER1/GDPD5/TOR1A/POLG/NRP1/DISC1/DNM2/L1CAM/CCDC120/ROR1/KIF20B/DCTN2/RAB5A/ITGA2/NDEL1/OLFM1/PTPRN2/KCNK2/ITGA3/KCNA2/CHRM2/RASGRF1/CDK5R2/UNC5C/PREX1/FSCN1/DVL1/PSEN1/FMR1/RAB3A/YWHAE/KATNB1/EXOC4/CAD/RUFY3/LMTK2/KIF5B/TRAK1/OPRD1/CABP4/HSP90AB1/ACAP3/TRPV4/BRSK1/APP/GHRH/SNCA/SIGMAR1/SSH1/TULP1/FGF13/BOC/UCN3/TENM2/PTCH1/PCDH9/TRPV2/NTSR1/NTRK2/NPTXR	111
CC	GO:0000932	P-body	34/7377	84/19717	0.3173	0.5339	0.382	ZFP36/C9orf72/SQSTM1/AGO2/MOV10/PSMA4/SAMD4B/DCP1B/DCP2/ZC3H12D/APOBEC3G/CAPRIN1/APOBEC3C/LSM14A/BTBD1/DCPS/PSMC3/TRIM21/XRN1/CPEB1/EDC4/AGO1/TNRC6B/TNRC6A/POLR2D/CNOT7/DIS3L2/EIF4E/PSMA2/PSMC2/SAMD4A/TOP1/EIF4ENIF1/UPF1	34
CC	GO:0097730	non-motile cilium	59/7377	149/19717	0.3181	0.5341	0.382	SPATA7/PKD2L1/HYLS1/LYAR/GNB1/TTC8/SHOC2/PKD2/IFT57/DHRS3/TULP3/KIFAP3/GNAQ/MYO5A/ARL13B/NAPEPLD/WDR19/PDE6G/RAB8A/MKKS/OCRL/RPGR/IFT52/RPGRIP1/BBS4/NPHP4/MAK/ELMOD3/OPN3/BBS7/LCA5/TBCC/FAM161A/CETN1/CETN2/C11orf74/MERTK/IFT20/GUCY2D/KIF17/PPEF2/NXNL1/PCDHB13/GRK4/INHA/PHLPP2/PCDHB15/TOPORS/CIB2/TULP1/CCDC66/PDC/CACNA1F/RAB27A/GNA11/RP1/OPN4/PTGS1/KNCN	59
CC	GO:0042383	sarcolemma	54/7377	136/19717	0.3189	0.5342	0.3822	SLC8A1/KCNJ5/EZR/ATP2B4/ANXA1/ATP1A1/SYNC/PLEC/CIB1/FLOT1/VCL/LAMP1/SLC9A1/PPP3CB/RDX/SCN1B/AHNAK/RYR1/DTNBP1/DMD/FKRP/CCDC78/RTN2/SNTB1/SRI/PGM5/FXYD1/ATP1B1/SSPN/OBSCN/KRT8/GOT2/CORO1C/PRX/CAMK2D/CAV3/STAC2/LAMA2/PSEN1/CASQ1/DTNA/TGFB3/CAPN3/CACNG6/COL6A3/CACNB3/SNTA1/ANXA2/DAG1/CIB2/ATP1A2/SLC8A3/BIN1/FGF6	54
CC	GO:0030286	dynein complex	21/7377	51/19717	0.337	0.5634	0.403	DYNC1LI1/DYNLL2/DNAL1/DISC1/DNAI2/DNAH17/DCTN2/DYNC2LI1/DYNLRB1/CCDC65/DYNLRB2/DYNLT3/DNAL4/DNAI1/WDR60/SNX4/DYNC1LI2/DNAH10/TOPORS/DNAH8/DNAH2	21
CC	GO:0000314	organellar small ribosomal subunit	12/7377	28/19717	0.3398	0.5656	0.4046	MRPS6/MRPS16/MRPS14/MRPL42/DAP3/MRPS34/MRPS33/MRPS18B/MRPS15/MRPS2/MRPS9/MRPS17	12
CC	GO:0005763	mitochondrial small ribosomal subunit	12/7377	28/19717	0.3398	0.5656	0.4046	MRPS6/MRPS16/MRPS14/MRPL42/DAP3/MRPS34/MRPS33/MRPS18B/MRPS15/MRPS2/MRPS9/MRPS17	12
CC	GO:0043292	contractile fiber	91/7377	234/19717	0.3426	0.5675	0.406	SLC8A1/SCO2/TRIM32/ATP2B4/PDLIM1/SYNC/PLEC/FLNA/MTMR12/FHL3/ACTN4/SQSTM1/KLHL41/TPM3/VCL/TMOD3/KAT2B/MYL6B/TWF2/PPP3CB/PARVB/PAK1/HSPB1/CFL2/PDLIM7/ACTN1/AHNAK/RYR1/HABP4/ACTC1/TNNI2/PDE4B/SVIL/ENO1/IDO1/MYBPC3/ALDOA/NEXN/ACTA2/PDE4DIP/DMD/HOMER1/SPTBN1/DNAJB6/TIMP4/PSEN2/SRI/ARF1/SYNE2/TPM4/PDLIM5/GLRX3/PGM5/TPM1/HDAC4/TNNC2/OBSCN/KLHL40/KRT8/SMPX/CORO1C/STUB1/MYL5/FLNB/MYOZ1/LMOD3/CAV3/MYZAP/FHL2/MYOM2/CASQ1/SLC4A1/CAPN3/CASQ2/HRC/SCN8A/LRRC39/SYNPO2L/MYH2/MMP2/CSRP1/DAG1/PDLIM4/NBR1/MYH3/GJA1/ACTA1/BIN1/TNNT1/MYOZ3/SYNPO	91
CC	GO:0005844	polysome	29/7377	72/19717	0.3485	0.5675	0.406	VIM/AGO2/PSMA1/EIF4B/LARP4/DHX9/RPL8/EIF4H/EIF2S1/NAA38/ATXN2/MCRS1/RPS21/FUS/AGO1/CALR/IMPACT/UNK/LARP4B/VBP1/FMR1/EIF4G1/RPL24/DIS3L2/MSI2/RPL32/EIF2AK4/PNPT1/RPL10A	29
CC	GO:0099092	postsynaptic density, intracellular component	8/7377	18/19717	0.3485	0.5675	0.406	FYN/BAIAP2/ABR/ARHGEF2/BCR/PRR7/SH3GL1/DNM2	8
CC	GO:0000782	telomere cap complex	6/7377	13/19717	0.3505	0.5675	0.406	XRCC5/ACD/CTC1/XRCC6/TERT/POT1	6
CC	GO:0000783	nuclear telomere cap complex	6/7377	13/19717	0.3505	0.5675	0.406	XRCC5/ACD/CTC1/XRCC6/TERT/POT1	6
CC	GO:0000800	lateral element	6/7377	13/19717	0.3505	0.5675	0.406	REC8/SYCP3/CCDC155/INCENP/BRCA1/SMC3	6
CC	GO:0005736	RNA polymerase I complex	6/7377	13/19717	0.3505	0.5675	0.406	POLR2L/POLR2H/POLR1C/POLR2F/POLR2K/CD3EAP	6
CC	GO:0030130	clathrin coat of trans-Golgi network vesicle	6/7377	13/19717	0.3505	0.5675	0.406	AFTPH/CLTB/AP1G2/CLTCL1/AP2A1/AP1G1	6
CC	GO:0033391	chromatoid body	6/7377	13/19717	0.3505	0.5675	0.406	TDRD6/NSUN2/TDRD7/CLOCK/EIF4E/ARNTL	6
CC	GO:0036038	MKS complex	6/7377	13/19717	0.3505	0.5675	0.406	TCTN1/B9D1/TCTN2/MKS1/TMEM231/TMEM107	6
CC	GO:0042627	chylomicron	6/7377	13/19717	0.3505	0.5675	0.406	LSR/APOC1/APOE/APOBR/APOA5/APOA1	6
CC	GO:0044292	dendrite terminus	6/7377	13/19717	0.3505	0.5675	0.406	IFT57/CYFIP1/IFT52/IFT20/HSP90AB1/PTCH1	6
CC	GO:0098845	postsynaptic endosome	6/7377	13/19717	0.3505	0.5675	0.406	RAB11A/GRIPAP1/ARC/RAB5A/STX12/PICK1	6
CC	GO:0016528	sarcoplasm	32/7377	80/19717	0.3552	0.574	0.4106	PLEC/MTMR12/KLHL41/AGL/ITPR1/RYR1/HABP4/TMEM109/DTNBP1/CCDC78/FABP3/RTN2/MRVI1/SRI/SYNE2/CALR/POMT1/CAMK2D/ATP2A2/HSP90B1/CASQ1/CASQ2/HRC/SPOCK1/TMEM38B/MANF/CALU/SLN/CHERP/SLC8A3/MEF2C/CAMK2B	32
CC	GO:0001750	photoreceptor outer segment	35/7377	88/19717	0.3611	0.5822	0.4165	SPATA7/LYAR/GNB1/SHOC2/DHRS3/GNAQ/MYO5A/NAPEPLD/WDR19/PDE6G/OCRL/RPGR/BBS4/MAK/OPN3/BBS7/MERTK/IFT20/GUCY2D/PPEF2/NXNL1/PCDHB13/GRK4/INHA/PHLPP2/CIB2/TULP1/CCDC66/PDC/CACNA1F/RAB27A/GNA11/RP1/OPN4/PTGS1	35
CC	GO:0072686	mitotic spindle	43/7377	109/19717	0.3639	0.5855	0.4189	NUP62/DIAPH1/EML4/PKD2/MAP4/MAPKBP1/CENPE/IKBKG/CAPG/EML3/KLHL22/CDK5RAP2/MAPRE1/SPAG5/TBCK/ESPL1/ASPM/NCOR1/MAK/BCCIP/YPEL5/KIF20B/NUSAP1/TTC28/DYNLT3/KATNA1/CLASP2/FAM161A/GPSM2/RCC2/KAT2A/MAPK1/SMC3/PKHD1/STAG1/TBL1X/MISP/AURKA/IK/EFHC1/TADA3/AAAS/RMDN2	43
CC	GO:0005902	microvillus	33/7377	83/19717	0.3681	0.5911	0.4229	MYO1G/ICAM2/EZR/AKR1B1/SYTL1/CD44/SCARB1/S100P/IQGAP2/TGFB1/RDX/STARD10/HYAL2/ATP6V1A/BBS2/ATP6V1B2/LRRK2/MYO1C/CLIC4/WWOX/ENPP7/CTSV/PDGFA/FSCN1/IFT20/MSN/EXOC4/ATP7A/CLCA1/CNP/PTPRH/ATP6V1B1/ANKS4B	33
CC	GO:0000315	organellar large ribosomal subunit	23/7377	57/19717	0.3701	0.5918	0.4234	C12orf65/MRPL35/MRPL45/MRPL40/MRPS30/MRPL34/MRPL54/MRPL44/MRPL33/MRPL51/MRPL49/MRPL3/MRPL42/MRPL4/MRPL20/MRPL46/MRPL24/MRPL36/MRPL48/MRPL41/MRPL2/MPV17L2/MRPL30	23
CC	GO:0005762	mitochondrial large ribosomal subunit	23/7377	57/19717	0.3701	0.5918	0.4234	C12orf65/MRPL35/MRPL45/MRPL40/MRPS30/MRPL34/MRPL54/MRPL44/MRPL33/MRPL51/MRPL49/MRPL3/MRPL42/MRPL4/MRPL20/MRPL46/MRPL24/MRPL36/MRPL48/MRPL41/MRPL2/MPV17L2/MRPL30	23
CC	GO:0005669	transcription factor TFIID complex	16/7377	39/19717	0.3771	0.6019	0.4306	ERCC4/GTF2E1/TAF11/TAF12/TAF5/GTF2H4/ERCC1/GTF2F1/TAF6L/TBPL1/GTF2A1/ERCC2/TAF9B/TAF4/TBP/TAF7	16
CC	GO:0099091	postsynaptic specialization, intracellular component	9/7377	21/19717	0.3796	0.6045	0.4324	FYN/LYN/BAIAP2/ABR/ARHGEF2/BCR/PRR7/SH3GL1/DNM2	9
CC	GO:0005795	Golgi stack	58/7377	149/19717	0.3805	0.6048	0.4326	LPCAT2/MOB4/CHSY1/MGAT2/ARAP1/FUT4/BCAP31/PSENEN/FUT7/LYPLA2/ASAP2/GOLGA8A/MGAT4B/TMEM87A/GOLGB1/SAR1B/NAGPA/PITPNM1/ATL1/B4GALT6/CSGALNACT1/CLN3/TOM1L1/NSFL1C/ST3GAL2/XYLT1/BET1/B3GALT6/OCRL/GOSR1/TMBIM4/SULF2/GCNT1/ZFYVE1/PLK3/GOLPH3L/GOLGA5/SGMS1/GAL3ST4/CSGALNACT2/STX16/FUT6/B4GALT5/HACE1/GGTA1P/ST3GAL1/VRK1/COG2/YIPF6/NECAB3/LLGL1/SCFD1/B4GALT1/CLIP3/GALNT1/GOLGA3/APH1A/MBTPS1	58
CC	GO:0044452	nucleolar part	69/7377	178/19717	0.3814	0.605	0.4328	JAZF1/EZR/CDCA7L/KLF6/SMAD7/FBLIM1/LIPA/WDR37/UBE2N/FHIT/RPP38/CHD1/TXNRD1/IP6K1/CHCHD1/COIL/PSPC1/RSAD2/SIRT7/AGER/POLR2L/SPATA2/CDKN2AIP/TAF1B/AFF4/INO80C/CD2BP2/NOLC1/POLR2H/SUMO1/FBL/RRP7A/AKNA/SNRPB2/NHP2/UTP15/ORC6/GAR1/DSN1/DDX46/TAF1D/POLR1C/WDR36/NFKBIE/POLR2F/LEO1/DCLRE1A/PEX14/SESN1/CRIPT/POLR2K/RPP40/HERC4/IMP4/NUFIP1/TAF1C/TFCP2L1/FBLL1/MTDH/SMARCA5/CD3EAP/SAMD4A/TOP1/PAX5/MALT1/NOP10/RRS1/SUPT20H/KDM4A	69
CC	GO:0005852	eukaryotic translation initiation factor 3 complex	7/7377	16/19717	0.3879	0.6104	0.4366	EIF3M/EIF3I/EIF3G/DDX3X/EIF3B/EIF3J/EIF3L	7
CC	GO:0034045	phagophore assembly site membrane	7/7377	16/19717	0.3879	0.6104	0.4366	ULK2/ATG14/WIPI1/ATG2B/WDR45B/ULK1/ATG12	7
CC	GO:0000235	astral microtubule	5/7377	11/19717	0.3962	0.6104	0.4366	PAFAH1B1/MAPRE1/DYNLT3/FAM161A/MISP	5
CC	GO:0005818	aster	5/7377	11/19717	0.3962	0.6104	0.4366	PAFAH1B1/MAPRE1/DYNLT3/FAM161A/MISP	5
CC	GO:0031680	G-protein beta/gamma-subunit complex	5/7377	11/19717	0.3962	0.6104	0.4366	GNG5/GNG7/GNG2/GNG11/GNG12	5
CC	GO:0032797	SMN complex	5/7377	11/19717	0.3962	0.6104	0.4366	DDX20/GEMIN6/GEMIN7/STRAP/FMR1	5
CC	GO:0034992	microtubule organizing center attachment site	5/7377	11/19717	0.3962	0.6104	0.4366	SUN2/CCDC155/CLMN/SYNE2/SPAG4	5
CC	GO:0034993	meiotic nuclear membrane microtubule tethering complex	5/7377	11/19717	0.3962	0.6104	0.4366	SUN2/CCDC155/CLMN/SYNE2/SPAG4	5
CC	GO:0042589	zymogen granule membrane	5/7377	11/19717	0.3962	0.6104	0.4366	STXBP2/SCAMP1/TMED10/DMBT1/CLCA1	5
CC	GO:0061827	sperm head	5/7377	11/19717	0.3962	0.6104	0.4366	DNAJB1/ALDOA/TACR1/HSP90AB1/TACR2	5
CC	GO:0106083	nuclear membrane protein complex	5/7377	11/19717	0.3962	0.6104	0.4366	SUN2/CCDC155/CLMN/SYNE2/SPAG4	5
CC	GO:0106094	nuclear membrane microtubule tethering complex	5/7377	11/19717	0.3962	0.6104	0.4366	SUN2/CCDC155/CLMN/SYNE2/SPAG4	5
CC	GO:1990907	beta-catenin-TCF complex	5/7377	11/19717	0.3962	0.6104	0.4366	LDB1/TLE1/TLE4/BCL9L/TCF7L2	5
CC	GO:0099738	cell cortex region	17/7377	42/19717	0.3963	0.6104	0.4366	CTBP2/PKD2/UNC13B/ENO1/CTSZ/SAPCD2/CLTB/CLASP2/MYL12B/GPSM2/HAMP/TCHP/PPFIA3/EPB41/EPB41L2/PRKCZ/RIMS2	17
CC	GO:0030684	preribosome	30/7377	76/19717	0.3967	0.6104	0.4366	ZNF622/WDR37/TSR1/EIF6/WDR46/UTP14A/KRI1/KRR1/ZNF593/WDR74/MRTO4/FBL/RRP7A/LAS1L/NIP7/NOC2L/FTSJ3/WDR36/DCAF13/LTV1/RRP15/RIOK2/NOL10/RIOK3/IMP4/NOC4L/FAM207A/FBLL1/UTP3/RRS1	30
CC	GO:0030016	myofibril	86/7377	224/19717	0.4051	0.6197	0.4433	SLC8A1/SCO2/TRIM32/ATP2B4/PDLIM1/SYNC/PLEC/FLNA/MTMR12/FHL3/ACTN4/SQSTM1/KLHL41/TPM3/VCL/TMOD3/KAT2B/TWF2/PPP3CB/PARVB/PAK1/HSPB1/CFL2/PDLIM7/ACTN1/AHNAK/RYR1/HABP4/ACTC1/TNNI2/PDE4B/SVIL/ENO1/MYBPC3/ALDOA/NEXN/PDE4DIP/DMD/HOMER1/SPTBN1/DNAJB6/TIMP4/PSEN2/SRI/ARF1/SYNE2/TPM4/PDLIM5/GLRX3/PGM5/TPM1/HDAC4/TNNC2/OBSCN/KLHL40/KRT8/SMPX/CORO1C/STUB1/FLNB/MYOZ1/LMOD3/CAV3/MYZAP/FHL2/MYOM2/CASQ1/SLC4A1/CAPN3/CASQ2/HRC/SCN8A/LRRC39/SYNPO2L/MYH2/MMP2/CSRP1/DAG1/PDLIM4/NBR1/MYH3/ACTA1/BIN1/TNNT1/MYOZ3/SYNPO	86
CC	GO:0034358	plasma lipoprotein particle	15/7377	37/19717	0.4065	0.6197	0.4433	PCYOX1/LSR/APOC1/PLA2G7/CETP/APOE/HDLBP/APOO/LDLR/APOBR/CLU/APOL1/APOA5/LCAT/APOA1	15
CC	GO:1990777	lipoprotein particle	15/7377	37/19717	0.4065	0.6197	0.4433	PCYOX1/LSR/APOC1/PLA2G7/CETP/APOE/HDLBP/APOO/LDLR/APOBR/CLU/APOL1/APOA5/LCAT/APOA1	15
CC	GO:0031233	intrinsic component of external side of plasma membrane	10/7377	24/19717	0.4067	0.6197	0.4433	RTN4R/FOLR2/CD59/HYAL2/FLT3LG/IGSF21/ADAM9/PKHD1/F3/CD24	10
CC	GO:0099522	region of cytosol	10/7377	24/19717	0.4067	0.6197	0.4433	STXBP5/CTBP2/BAIAP2/FBXO45/HOMER1/LRRK2/EIF4E/PIN1/MTOR/DAG1	10
CC	GO:0070469	respiratory chain	39/7377	100/19717	0.4079	0.6203	0.4437	C15orf48/UQCRC2/UQCR11/NDUFA8/HIGD1A/NDUFC1/NDUFB11/NDUFS3/NDUFA3/NDUFA11/UQCR10/COX7A2L/NDUFA4/COX4I2/NDUFA1/WDR93/OXA1L/COX15/NDUFA10/NDUFB1/NDUFB5/UQCRQ/NDUFS1/COA3/NDUFB8/SURF1/NDUFB6/NDUFB3/SDHA/NDUFS7/NDUFV2/ND4/SDHD/UQCRB/NDUFB2/NNT/NDUFS2/NDUFA7/COX7B	39
CC	GO:0016514	SWI/SNF complex	8/7377	19/19717	0.419	0.636	0.4549	ARID1B/BRD9/SS18/SMARCC2/RB1/NCR1/SMARCC1/ACTL6A	8
CC	GO:0045177	apical part of cell	146/7377	384/19717	0.4212	0.638	0.4564	ATP6V0D2/FN1/EZR/SLC22A4/DLL1/ANXA1/SLC29A1/ARHGEF18/DRAM2/ATP1A1/SLC23A2/MGAM/PFKM/GM2A/SLC22A18/ATP6V1C1/SNX10/CIB1/LGMN/CD44/SLC22A5/DCHS1/HFE/DVL2/SLC9A1/SLC2A9/RAPGEF6/NAALADL1/PTPRO/PLD1/DPP4/EXOC1/RDX/VASH1/RAPGEF2/CD36/PCM1/STXBP2/AKR1A1/P2RY6/HYAL2/TCIRG1/SLC7A5/VAMP3/ATP6V1A/SAPCD2/CSPG4/NUMB/AGER/LDLR/C2CD2L/PLB1/LRP1/ATP8B1/SLC22A12/ATP6AP2/IGFBP2/HOMER1/ATP1B2/ATP6V1B2/IFIT5/ASPM/CLIC4/PSEN2/PTK2/MLC1/EDA/SLC12A2/MUC1/EMP2/MGST1/EDAR/FXYD1/WDPCP/ATP1B1/SIPA1L3/ADRB2/DYNC2LI1/LCT/UPK1B/GPR143/DAB1/SLC46A1/ABCB4/CTSV/CYBA/ABCB11/SLC4A5/KCNK2/PARD6B/AP2A1/SLC26A4/AHCYL1/AQP6/EGFR/ADAM17/SLC5A8/KL/PRKAA1/SLC17A4/HAMP/TCHP/P2RY4/CNTFR/MSN/SLC4A7/ITGA8/SRR/ATP7A/TMEM30A/PKHD1/CD34/NHS/HSP90AB1/SPTBN2/SLC12A1/REN/CACNB3/STXBP3/MTDH/PRKCZ/PTPRH/MREG/HPN/KCNMA1/TRPV4/C5AR2/APP/UPK2/SLC9B2/P2RX2/ATP6V1B1/AMOTL1/SHROOM1/CLCN5/GJA1/LZTS1/ERBB3/RAB27A/P2RY1/UPK1A/SLC29A4/KISS1/BMPR2/KNCN/SLC9A3R2	146
CC	GO:0098800	inner mitochondrial membrane protein complex	52/7377	135/19717	0.4271	0.6454	0.4617	C15orf48/CHCHD6/TIMM23B/IMMP1L/UQCRC2/NDUFA8/NDUFC1/NDUFB11/APOO/MCU/NDUFS3/NDUFA3/DNAJC19/TIMM17A/NDUFA11/CHCHD10/TIMM21/UQCR10/GRPEL1/AFG3L2/TIMM10B/NDUFA4/IMMP2L/GRPEL2/COX4I2/NDUFA1/WDR93/NDUFA10/MICU1/NDUFB1/NDUFB5/UQCRQ/NDUFS1/COA3/TIMM22/AGK/NDUFB8/DNAJC15/NDUFB6/NDUFB3/SDHA/NDUFS7/NDUFV2/ND4/SDHD/UQCRB/NDUFB2/TIMM50/APOOL/NDUFS2/MICU2/NDUFA7	52
CC	GO:0005881	cytoplasmic microtubule	27/7377	69/19717	0.4284	0.6454	0.4617	TUBA1A/BCL10/CLIP1/SCTR/PAFAH1B1/MAPRE1/MAPRE2/CYLD/SERP1/BICD1/BCAS3/DYNC2LI1/TMEM214/DYNLT3/TUBG2/CLASP2/FAM161A/SS18/KIF2C/TUBA1B/FAM161B/CLIP2/MISP/TRPV4/RAB3D/CYP2A6/TTC30B	27
CC	GO:0030017	sarcomere	78/7377	204/19717	0.4299	0.6454	0.4617	SLC8A1/TRIM32/ATP2B4/PDLIM1/SYNC/FLNA/MTMR12/FHL3/ACTN4/SQSTM1/KLHL41/TPM3/TMOD3/KAT2B/PPP3CB/PARVB/PAK1/HSPB1/CFL2/PDLIM7/ACTN1/RYR1/HABP4/ACTC1/TNNI2/PDE4B/ENO1/MYBPC3/ALDOA/NEXN/DMD/HOMER1/SPTBN1/DNAJB6/TIMP4/PSEN2/SRI/ARF1/SYNE2/TPM4/PDLIM5/GLRX3/PGM5/TPM1/HDAC4/TNNC2/OBSCN/KLHL40/KRT8/SMPX/CORO1C/STUB1/FLNB/MYOZ1/LMOD3/CAV3/MYZAP/FHL2/MYOM2/CASQ1/SLC4A1/CAPN3/CASQ2/HRC/SCN8A/LRRC39/SYNPO2L/MYH2/MMP2/CSRP1/PDLIM4/NBR1/MYH3/ACTA1/BIN1/TNNT1/MYOZ3/SYNPO	78
CC	GO:0005689	U12-type spliceosomal complex	11/7377	27/19717	0.4308	0.6454	0.4617	SNRNP25/SNRPB/RBM41/PDCD7/LSM7/SNRPD1/SNRPF/SF3B4/ZCRB1/SNRPG/SNRPD2	11
CC	GO:0030137	COPI-coated vesicle	11/7377	27/19717	0.4308	0.6454	0.4617	COPE/ARFGAP3/TMED10/CCDC88A/ARF1/KDELR3/COPG2/COPA/KDELR2/ARCN1/COPZ2	11
CC	GO:0000940	condensed chromosome outer kinetochore	6/7377	14/19717	0.4336	0.6454	0.4617	SPDL1/SKA2/NDC80/BOD1L1/BOD1/SKA3	6
CC	GO:0010369	chromocenter	6/7377	14/19717	0.4336	0.6454	0.4617	CBX5/CBX1/MBD5/INCENP/FMR1/SCMH1	6
CC	GO:0031314	extrinsic component of mitochondrial inner membrane	6/7377	14/19717	0.4336	0.6454	0.4617	COQ7/COQ5/COQ3/COQ6/NOA1/COQ4	6
CC	GO:0043083	synaptic cleft	6/7377	14/19717	0.4336	0.6454	0.4617	DNM3/LAMB2/APOE/C1QL1/LAMA2/CBLN1	6
CC	GO:0097546	ciliary base	14/7377	35/19717	0.4381	0.6509	0.4656	PRKAR2B/PRKACB/TULP3/RAB8A/IFT52/NPHP4/DISC1/C8orf37/PRKACA/IFT20/MOK/WDR60/TRAF3IP1/NEK8	14
CC	GO:0005682	U5 snRNP	9/7377	22/19717	0.4457	0.6596	0.4718	SNRNP200/SNRPB/TXNL4A/CD2BP2/SNRPD1/PRPF8/SNRPN/SNRPG/SNRPD2	9
CC	GO:0097225	sperm midpiece	9/7377	22/19717	0.4457	0.6596	0.4718	SQSTM1/DEFB1/IFT172/CCR6/HYAL3/TACR1/LYZL6/IFT81/TACR2	9
CC	GO:0005719	nuclear euchromatin	12/7377	30/19717	0.4524	0.6657	0.4762	KLF4/ALKBH1/RUVBL2/CREB1/SIRT1/PPARGC1A/TRIM24/CBX3/NSMF/TBP/TRNP1/NR1H4	12
CC	GO:0005834	heterotrimeric G-protein complex	12/7377	30/19717	0.4524	0.6657	0.4762	GNAI3/GNB1/GNA15/GNG5/GNG7/GNAQ/GNG2/GNAI2/GNA13/GNG11/GNG12/GNA11	12
CC	GO:1905360	GTPase complex	12/7377	30/19717	0.4524	0.6657	0.4762	GNAI3/GNB1/GNA15/GNG5/GNG7/GNAQ/GNG2/GNAI2/GNA13/GNG11/GNG12/GNA11	12
CC	GO:0005858	axonemal dynein complex	7/7377	17/19717	0.4637	0.6785	0.4854	DNAL1/DNAI2/DNAH17/CCDC65/DNAI1/DNAH8/DNAH2	7
CC	GO:0030014	CCR4-NOT complex	7/7377	17/19717	0.4637	0.6785	0.4854	ZFP36/TOB1/TNKS1BP1/CNOT4/CPEB3/CNOT7/CNOT10	7
CC	GO:0099524	postsynaptic cytosol	7/7377	17/19717	0.4637	0.6785	0.4854	BAIAP2/FBXO45/HOMER1/EIF4E/PIN1/MTOR/DAG1	7
CC	GO:0005657	replication fork	27/7377	70/19717	0.4654	0.6796	0.4862	BCL6/UHRF1/RPA1/ETAA1/PRIM2/PURA/POLD4/RAD51B/DONSON/POLD2/BCAS2/SMARCAD1/TIPIN/RFC3/POLH/PCNA/TIMELESS/GINS4/POLD1/POLA1/PRPF19/POLA2/SMARCA5/TOP1/UBE2B/TONSL/ZRANB3	27
MF	GO:0017016	Ras GTPase binding	217/7116	429/17697	6.96e-06	0.00486	0.004294	CDC42EP4/CDC42SE1/ARHGEF18/DENND5A/SOD1/FMNL3/ATP6AP1/FMNL1/C9orf72/RASGEF1A/DIAPH1/PLEKHG2/SPATA13/IPO13/MYO9B/RNF41/HPS4/RASGEF1B/FLNA/ARHGEF3/MLPH/SYTL1/ADPRH/CIB1/RASGRP3/DENND1A/ALS2/RABGAP1L/STXBP5/TBC1D15/FGD6/FGD5/DVL2/AKAP13/ARHGDIA/TNPO1/RAPGEF6/IQGAP2/ARHGEF10L/DENND4A/MICAL1/ARHGEF40/TBC1D5/DENND1B/SH3BP4/KIF3B/EXOC1/DAAM1/PFN1/CDC42EP2/UNC13B/NXT1/PAK1/RAPGEF2/KCTD10/RANBP9/MYO5A/SGSM1/RASSF5/PPP6R1/MICALL1/TBC1D1/NCF2/BICD2/DENND2D/DENND3/RCBTB2/RUSC2/CDC42SE2/ITSN1/RGL1/ADRB1/TRAPPC5/ABR/NET1/DIAPH2/ARHGDIB/ARHGEF6/SRGAP2C/SRGAP3/RAB3GAP1/PAK2/GDI1/RAB11FIP4/GDI2/RASGRP1/RIN2/ARHGEF2/RAP1A/TBC1D2/ANKRD27/RABGAP1/EHD1/SH3BP5L/RAB8A/XPOT/TBCK/SH3BP1/RAC1/DENND6B/NDRG1/RAB29/RGL3/KALRN/OCRL/CDC42EP3/NOXA1/LRRK2/CYFIP1/MYO1C/PDE6D/RCC1/MYCBP2/DENND4C/TBC1D12/STK19/BICD1/KIF16B/BCR/IPO4/TMEM127/SRGAP2/TBC1D17/SBF1/RPH3AL/TBC1D9B/TBC1D20/GOLGA5/TBC1D13/MICALL2/UNC13D/CSE1L/TBC1D8/TRIOBP/SYTL4/TBC1D8B/RANGRF/MAP3K11/TBC1D7/VPS52/YBX3/TBC1D22A/OBSCN/RABGEF1/PARD6B/CORO1C/DNM1L/RHOH/HACE1/RASGRF1/ULK1/VAV1/PKN2/RCC2/IPO9/DOCK11/PREX1/ITSN2/ANXA2P2/RALGPS1/DVL1/AP1G1/TRAPPC3/RALBP1/IPO7/IFT20/RUNDC1/SMCR8/INF2/SYTL2/EXOC4/TBC1D21/HPS6/ARHGEF37/FGD3/NUP50/RHOBTB3/EVI5/LLGL1/ATP7A/AP3M1/STRN3/DENND5B/TBC1D10C/MAPKAP1/ARHGEF17/RIN1/CLEC16A/KNDC1/FGD4/DENND4B/OPTN/EPS8L2/SRGAP1/ANXA2/DENND6A/SBF2/DENND2A/ACAP2/CHM/GRTP1/RGP1/RIMS2/ARHGEF4/KPNB1/WAS/PICALM/ROCK2/DAAM2/MCF2L/NCKAP1/ARHGEF9/GAS8/TBC1D10B/RASGRP4/EXOC2/DMXL2	217
MF	GO:0019207	kinase regulator activity	114/7116	207/17697	9.926e-06	0.00486	0.004294	KLF4/ITPRIP/FAM20A/RAC2/PRKAR2B/CDKN2D/CDKN1A/SOCS3/BCL10/CCNL1/CCND3/WDR91/CHP1/MAP2K1/CIB1/ALS2/WDR81/RGCC/GSTP1/ELP4/GPRC5B/CISH/CXCL10/ERCC6/TESC/PIK3R3/CCND2/KAT2B/HEXIM1/CDC37/CDK4/TGFB1/TAOK3/SOCS5/HSPB1/PKIB/GMFG/ETAA1/NRG1/HYAL2/MBIP/CCNG1/DBF4B/ITSN1/SOCS6/DUS2/NCK1/CDKN2B/CASP3/SFN/NPM1/CCNH/PAK2/PARP16/TOM1L1/CCL5/CDKN1C/PIK3R6/CSNK2B/ATG13/SH3BP5L/HEXIM2/CCND1/DUSP19/SOCS7/MLST8/DDX3X/PRKAG2/TAB1/BCCIP/CCNE1/ELP3/MARK2/CDKN1B/CDKN2C/CCNK/TRIB2/DAZAP2/CCNL2/MAP2K2/GSKIP/RHOH/CDK5R2/SPRED1/CCNY/SPRY2/CCNA1/SMCR8/SOCS1/CCNC/CCNYL1/PRKAG1/FGFR1OP/HSP90AB1/CCNA2/YWHAG/SLA2/PKIA/CCNT1/MOB1B/CCNYL2/MALT1/CCKBR/CCNG2/CCNB3/FGF13/STRADA/SOCS2/GREM1/DAXX/CD24/ERBB3/GHRL/CCNF	114
MF	GO:0031267	small GTPase binding	222/7116	443/17697	1.234e-05	0.00486	0.004294	CDC42EP4/RILPL1/CDC42SE1/ARHGEF18/DENND5A/SOD1/FMNL3/ATP6AP1/FMNL1/C9orf72/RASGEF1A/DIAPH1/PLEKHG2/SPATA13/IPO13/GGA2/MYO9B/RNF41/HPS4/RASGEF1B/FLNA/ARHGEF3/MLPH/SYTL1/ADPRH/CIB1/RASGRP3/DENND1A/ALS2/RABGAP1L/STXBP5/TBC1D15/FGD6/FGD5/DVL2/AKAP13/ARHGDIA/TNPO1/RAPGEF6/IQGAP2/ARHGEF10L/DENND4A/MICAL1/ARHGEF40/TBC1D5/DENND1B/SH3BP4/KIF3B/EXOC1/DAAM1/PFN1/CDC42EP2/UNC13B/NXT1/PAK1/RAPGEF2/KCTD10/RANBP9/MYO5A/SGSM1/RASSF5/PPP6R1/MICALL1/TBC1D1/NCF2/BICD2/DENND2D/DENND3/RCBTB2/RUSC2/CDC42SE2/ITSN1/RGL1/ADRB1/TRAPPC5/ABR/NET1/DIAPH2/ARHGDIB/ARHGEF6/SRGAP2C/SRGAP3/RAB3GAP1/ABCA1/PAK2/GDI1/RAB11FIP4/GDI2/RASGRP1/RIN2/ARHGEF2/RAP1A/TBC1D2/ANKRD27/RABGAP1/EHD1/SH3BP5L/RAB8A/XPOT/TBCK/SH3BP1/RAC1/DENND6B/NDRG1/RAB29/RGL3/KALRN/OCRL/CDC42EP3/NOXA1/LRRK2/CYFIP1/MYO1C/PDE6D/RCC1/MYCBP2/DENND4C/TBC1D12/STK19/BICD1/KIF16B/BCR/IPO4/TMEM127/SRGAP2/TBC1D17/SBF1/RPH3AL/TBC1D9B/TBC1D20/GOLGA5/TBC1D13/MICALL2/UNC13D/CSE1L/TBC1D8/GRASP/TRIOBP/SYTL4/TBC1D8B/RANGRF/MAP3K11/TBC1D7/VPS52/YBX3/TBC1D22A/OBSCN/RABGEF1/PARD6B/CORO1C/DNM1L/RHOH/HACE1/RASGRF1/ULK1/VAV1/PKN2/RCC2/IPO9/DOCK11/PREX1/ITSN2/ANXA2P2/RALGPS1/DVL1/AP1G1/TRAPPC3/RALBP1/IPO7/IFT20/RUNDC1/SMCR8/INF2/SYTL2/EXOC4/TBC1D21/HPS6/ARHGEF37/FGD3/NUP50/RHOBTB3/EVI5/LLGL1/ATP7A/AP3M1/STRN3/DENND5B/TBC1D10C/MAPKAP1/ARHGEF17/RIN1/CLEC16A/KNDC1/FGD4/DENND4B/OPTN/EPS8L2/SRGAP1/ANXA2/DENND6A/SBF2/DENND2A/ACAP2/CHM/GRTP1/RGP1/RIMS2/ARHGEF4/KPNB1/WAS/PICALM/ROCK2/ADCYAP1R1/DAAM2/MCF2L/NCKAP1/ARHGEF9/GAS8/TBC1D10B/RASGRP4/EXOC2/DMXL2	222
MF	GO:0017137	Rab GTPase binding	98/7116	175/17697	1.625e-05	0.00486	0.004294	DENND5A/ATP6AP1/C9orf72/HPS4/MLPH/SYTL1/ADPRH/DENND1A/ALS2/RABGAP1L/STXBP5/TBC1D15/DENND4A/MICAL1/TBC1D5/DENND1B/UNC13B/MYO5A/SGSM1/MICALL1/TBC1D1/BICD2/DENND2D/DENND3/RUSC2/TRAPPC5/RAB3GAP1/GDI1/RAB11FIP4/GDI2/RIN2/TBC1D2/ANKRD27/RABGAP1/EHD1/SH3BP5L/RAB8A/TBCK/RAC1/DENND6B/NDRG1/RAB29/PDE6D/DENND4C/TBC1D12/BICD1/KIF16B/TMEM127/TBC1D17/SBF1/RPH3AL/TBC1D9B/TBC1D20/GOLGA5/TBC1D13/MICALL2/UNC13D/TBC1D8/SYTL4/TBC1D8B/TBC1D7/VPS52/TBC1D22A/RABGEF1/DNM1L/HACE1/ULK1/ANXA2P2/AP1G1/TRAPPC3/IFT20/RUNDC1/SMCR8/SYTL2/TBC1D21/HPS6/RHOBTB3/EVI5/LLGL1/AP3M1/DENND5B/TBC1D10C/CLEC16A/DENND4B/OPTN/ANXA2/DENND6A/SBF2/DENND2A/ACAP2/CHM/GRTP1/RGP1/RIMS2/PICALM/GAS8/TBC1D10B/DMXL2	98
MF	GO:0003725	double-stranded RNA binding	47/7116	75/17697	6.921e-05	0.01489	0.01316	DDX21/STAU2/VIM/AGO2/OASL/DDX60/ZFR/LRRFIP1/ACTN1/STAU1/SIDT1/MBNL1/DDX58/ADARB1/DUS2/OAS3/EIF4B/APTX/DHX9/OAS2/MRPL44/EIF4H/ILF2/LSM14A/DDX3X/ILF3/DICER1/IFIH1/TARBP2/AGO1/DDX1/YRDC/EIF2AK2/TFRC/TLR8/FMR1/SUPV3L1/MSN/TUBA1B/HSP90AB1/TLR3/DROSHA/MTDH/ADAR/SIDT2/STRBP/RFTN1	47
MF	GO:0044389	ubiquitin-like protein ligase binding	157/7116	308/17697	7.469e-05	0.01489	0.01316	STAM/PRKAR2B/CDKN1A/BCL10/LYN/HLTF/PINK1/SKI/PARP9/TXNIP/SYT11/TMBIM6/CUL1/SLC22A18/TNFRSF14/SMAD5/SMAD7/CD40/DDRGK1/FBXW7/STAT1/SMAD2/UCHL1/SQSTM1/CEBPB/VCL/UBE2N/PRKACB/FHIT/NFKBIA/ATP6V0C/GSK3B/RELA/TPI1/TRIM37/UBE2K/ZNF746/ARRB1/HIF1A/MAP1LC3A/WFS1/SMC6/PTK2B/ERLIN1/UBE2D3/UBXN7/TRAF6/DBT/IKBKG/DDX58/PTPN22/TRAF3/UBE2D2/HSPA5/DTX1/UBE2L6/CASP8/HERC2/XRCC5/NLK/UBE2J1/UBE2W/ERLIN2/PML/UBE2A/CLU/GPI/EIF4E2/MFHAS1/EGR2/ACVR1B/SLC25A5/PPARGC1A/MAP1LC3C/CCDC50/SUMO1/GLMN/HSPBP1/PRR7/DTX3L/NPLOC4/BCL2/UBE2D4/TSG101/PRDX6/TRIB2/TOLLIP/PRKACA/TRIOBP/DERL1/HGS/UBC/DET1/PCBP2/CACUL1/NKD2/RFFL/UBE2C/FZD5/TRAF1/RRAGA/STUB1/DNM1L/CALR/RNF20/FANCL/HSPA1L/CACYBP/PXN/ATXN3/LAPTM4B/BRCA1/EGFR/MUL1/YOD1/SPOPL/TRAF2/BAG2/USP7/FZD4/MDM2/YWHAE/CUL2/TUBA1B/SHPRH/TRAF5/UBXN1/JAK1/SUMO4/MOAP1/DNAJA1/STX8/CUL4B/GABARAPL1/HSP90AB1/RB1/UBE2G1/PER3/SNCAIP/CUL9/VCP/AURKA/RTN4/SNX9/RBX1/BAG5/TRAF4/USP19/DIO2/PSMD1/ATXN3L/UBE2B/DAXX/NDUFS2/ERBB3/PA2G4/KDM4A	157
MF	GO:0016780	phosphotransferase activity, for other substituted phosphate groups	16/7116	19/17697	0.0001083	0.01669	0.01475	CDS1/SGMS2/GNPTG/CHPT1/PTDSS2/PIGN/GNPTAB/SAMD8/PIGF/CDIPT/CRLS1/SGMS1/PIGO/AASDHPPT/PGS1/DPAGT1	16
MF	GO:0004896	cytokine receptor activity	57/7116	96/17697	0.0001116	0.01669	0.01475	IL2RG/CCR2/CX3CR1/IL27RA/IL1R2/IL17RA/IL13RA1/ACKR3/CD44/IL4R/IFNAR1/CD74/IL1RAP/IL7R/IL21R/IFNGR2/CSF2RA/CSF2RB/IL18R1/IL3RA/IL20RB/FLT3/EPOR/IL2RB/CMKLR1/IL6ST/IL1R1/CXCR1/CCR5/IL15RA/GFRA2/GFRA4/CCR6/IL12RB1/CXCR6/CCR4/EBI3/CCR3/IFNGR1/CXCR2/FZD4/IL13RA2/GPR35/CNTFR/CSF3R/CD4/IFNAR2/F3/IL12B/IL18RAP/CXCR3/GHR/CCR7/ACKR2/IL17RB/CCRL2/IL17RC	57
MF	GO:0060589	nucleoside-triphosphatase regulator activity	172/7116	344/17697	0.0001302	0.0173	0.01528	HTR2B/SIPA1L1/TBC1D24/RALGDS/CDC42SE1/TSC1/ARHGAP31/STARD8/VPS9D1/ARAP1/MYO9B/ARAP3/ALDH1A1/ADPRH/STARD13/RGS2/RASGRP3/RABGAP1L/AGFG1/RGS1/STXBP5/TBC1D15/ARHGDIA/FAM13A/IQGAP2/ARHGEF10L/ASAP2/ARHGAP27/TBC1D5/SH3BP4/ELMOD2/ARHGAP30/PFN1/DNAJB1/CDC42EP2/ARHGAP20/ARRB1/ARHGAP25/GNAQ/RAPGEF2/SGSM1/TBC1D1/ARHGAP19/ABR/ARHGDIB/RASA2/DNAJC19/ARHGAP22/ARHGEF6/SRGAP3/OPHN1/RGS12/RAB3GAP1/ARFGAP3/MYBPC3/GDI1/RP2/ARHGAP26/GDI2/RIN2/RASAL3/TBC1D2/ANKRD27/TAGAP/RABGAP1/NPRL3/GRPEL1/TBCK/SH3BP1/ATP1B2/AGAP4/GPSM1/ARHGAP24/OCRL/LRRK2/DNAJC1/PDE6D/FLCN/DOCK5/DNAJB6/TBC1D12/KRIT1/HSPBP1/ARHGAP6/BCR/ATP1B3/ARHGAP12/RALGAPB/GTF2H4/RGS3/DNAJB4/SRGAP2/RASA3/GRPEL2/FNIP1/TBC1D17/GPSM3/NRP1/TBC1D9B/TBC1D20/TBC1D13/RGS14/ATP1B1/TBC1D8/SIPA1L3/ARHGAP18/DNAJC10/ACAP1/SYNGAP1/TBC1D8B/RGS5/TBC1D7/EIF5/TBC1D22A/DNM1L/RHOH/GARNL3/PLCB1/RABEP1/GMIP/GPSM2/BAG2/PREX1/SLIT2/DNAJC15/RALBP1/IPO7/RAB3A/RUNDC1/NPRL2/HSCB/RASAL1/ADAP1/TBC1D21/RGS20/NUP50/EVI5/LLGL1/DNAJA1/TBC1D10C/RALGAPA2/RIN1/ACAP3/AGAP3/RGS6/AGAP1/ALS2CL/CHN2/SRGAP1/GPS1/ACAP2/DEPDC5/CHM/ITGB1BP1/GRTP1/RGS16/SIPA1L2/ARL2BP/ADAP2/ASAP1/RGS17/RUNDC3A/WAS/DNAJC24/SYDE1/PREB/ASAP3/SESN2/SMAP2/ARFGAP1/TBC1D10B/CPEB2	172
MF	GO:0051019	mitogen-activated protein kinase binding	20/7116	26/17697	0.0001557	0.01736	0.01534	DUSP1/GCH1/ATF7/DUSP10/MICALCL/MAPKAPK3/PTAFR/MAPK7/DUSP2/ABL1/PPM1D/SIRT1/MAPKAPK5/TAB1/MAPKAPK2/TNIP1/NFATC1/NBR1/PRMT1/PTPRJ	20
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	72/7116	128/17697	0.00017	0.01736	0.01534	HSD17B14/ALDH3A2/LDHA/HADHB/HIBADH/CBR4/MDH1/KCNAB2/AKR1B1/HADH/RDH10/PTGR1/CRYL1/ADH5/ME1/CTBP2/AKR1C3/HMGCR/ZADH2/AKR7A2/PTGR2/DHRS3/DHRS9/AKR7A3/HPGD/AKR1A1/DHDH/RDH16/IMPDH1/BMP2/AKR1C1/ME3/HSD11B1/HSD17B4/IDH1/BDH1/LDHB/RDH12/G6PD/BDH2/ADHFE1/IDH2/SPR/LDHC/CBR3/VKORC1/LDHAL6B/HSD17B10/MDH1B/KCNAB1/EHHADH/RDH5/SORD/HADHA/AKR1B10/ADH1B/IDH3A/KDSR/HSD17B3/PGD/L2HGDH/ABCC4/SDR42E1/GRHPR/ME2/IDH3G/CHDH/PHGDH/ALDH3A1/ADH7/HSD17B12/HAO1	72
MF	GO:0031625	ubiquitin protein ligase binding	147/7116	290/17697	0.0001742	0.01736	0.01534	PRKAR2B/CDKN1A/BCL10/LYN/HLTF/PINK1/SKI/TXNIP/SYT11/TMBIM6/CUL1/SLC22A18/TNFRSF14/SMAD5/SMAD7/CD40/FBXW7/SMAD2/UCHL1/SQSTM1/VCL/UBE2N/PRKACB/FHIT/NFKBIA/ATP6V0C/GSK3B/RELA/TPI1/TRIM37/UBE2K/ZNF746/ARRB1/HIF1A/MAP1LC3A/WFS1/SMC6/PTK2B/ERLIN1/UBE2D3/UBXN7/TRAF6/DBT/IKBKG/DDX58/PTPN22/TRAF3/UBE2D2/HSPA5/DTX1/UBE2L6/CASP8/HERC2/XRCC5/NLK/UBE2J1/UBE2W/ERLIN2/PML/UBE2A/CLU/GPI/EIF4E2/MFHAS1/EGR2/ACVR1B/SLC25A5/PPARGC1A/MAP1LC3C/CCDC50/SUMO1/GLMN/HSPBP1/NPLOC4/BCL2/UBE2D4/TSG101/PRDX6/TRIB2/TOLLIP/PRKACA/TRIOBP/DERL1/UBC/DET1/PCBP2/CACUL1/NKD2/RFFL/FZD5/TRAF1/RRAGA/STUB1/DNM1L/CALR/RNF20/FANCL/HSPA1L/CACYBP/PXN/ATXN3/LAPTM4B/BRCA1/EGFR/MUL1/YOD1/SPOPL/TRAF2/BAG2/USP7/FZD4/MDM2/YWHAE/CUL2/TUBA1B/SHPRH/TRAF5/UBXN1/JAK1/MOAP1/DNAJA1/STX8/CUL4B/GABARAPL1/HSP90AB1/RB1/UBE2G1/PER3/SNCAIP/CUL9/VCP/AURKA/RTN4/SNX9/RBX1/BAG5/TRAF4/USP19/DIO2/PSMD1/ATXN3L/UBE2B/DAXX/NDUFS2/ERBB3/PA2G4/KDM4A	147
MF	GO:0051287	NAD binding	36/7116	56/17697	0.00023	0.02116	0.01869	LDHA/HIBADH/MDH1/GAPDH/HADH/ALDH1A1/SIRT4/AHCY/CRYL1/ME1/CTBP2/HPGD/NUDT6/SIRT7/ALDH2/ME3/QDPR/IDH1/SIRT1/GLUD1/LDHB/BDH2/IDH2/SIRT5/SORD/CYB5R3/HADHA/IDH3A/GRHPR/ME2/IDH3G/AOX1/PHGDH/NNT/NDUFS2/GLYR1	36
MF	GO:0000287	magnesium ion binding	111/7116	213/17697	0.0002705	0.02163	0.01911	RPS6KA2/MAPK12/PINK1/ENOSF1/OXSR1/ATP8B2/PGM3/MTHFD2/ATP8A1/TDP2/HMGCL/PPA1/RPS6KA3/PSPH/ADPRH/SIK1/MAP3K8/PRKACB/IRAK3/S100P/STK38L/TESC/RAN/PKM/DYRK2/IRAK4/MORC2/LATS1/PRPSAP1/ATP11B/ABL1/ATP4A/ENO1/GCLC/ENOPH1/ATP10A/RP2/NLK/PPA2/SIK2/SRPK2/MARK1/ADPRHL2/ATP8B1/IDH1/MOV10L1/PRTFDC1/LRRK2/TDG/IDH2/PAPOLA/RNASEH1/MTPAP/XYLT2/ARF1/SPHK1/PGM2/PPM1N/PGM5/NUDT3/UBA2/MARK2/ALPP/NME1/MAP3K6/PRKACA/PI4K2A/NUDT5/GSS/PRPS1/GEN1/HPGDS/FOXK2/SRPK1/MAP3K5/SUCLG2/DYRK3/NUDT7/AASDHPPT/ABL2/IDH3A/XXYLT1/CLYBL/ENO2/THTPA/CIB4/WEE1/PRPS1L1/DXO/SRR/DIS3L2/CERK/ADPRHL1/PRPS2/DCTPP1/NT5C3A/IDH3G/BRSK1/ERN1/SNCA/CIB2/LHPP/DUT/NUDT16/HACL1/FEN1/ENDOV/TOP2A/ATP10B/FIGNL1/IMPA1	111
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	67/7116	119/17697	0.0002712	0.02163	0.01911	HSD17B14/LDHA/HADHB/HIBADH/CBR4/MDH1/KCNAB2/AKR1B1/HADH/RDH10/PTGR1/CRYL1/ADH5/ME1/CTBP2/AKR1C3/HMGCR/ZADH2/AKR7A2/PTGR2/DHRS3/DHRS9/AKR7A3/HPGD/AKR1A1/DHDH/RDH16/IMPDH1/BMP2/AKR1C1/ME3/HSD11B1/HSD17B4/IDH1/BDH1/LDHB/RDH12/G6PD/BDH2/ADHFE1/IDH2/SPR/LDHC/CBR3/LDHAL6B/HSD17B10/MDH1B/KCNAB1/EHHADH/RDH5/SORD/HADHA/AKR1B10/ADH1B/IDH3A/KDSR/HSD17B3/PGD/ABCC4/SDR42E1/GRHPR/ME2/IDH3G/PHGDH/ALDH3A1/ADH7/HSD17B12	67
MF	GO:0035325	Toll-like receptor binding	11/7116	12/17697	0.0003353	0.02232	0.01973	MYD88/S100A9/S100A8/TLR1/TLR2/LY96/CD36/TOLLIP/UNC93B1/TIRAP/TLR6	11
MF	GO:0061578	Lys63-specific deubiquitinase activity	11/7116	12/17697	0.0003353	0.02232	0.01973	TNFAIP3/CYLD/OTUD4/OTUD5/DESI2/STAMBPL1/USP27X/ATXN3/YOD1/STAMBP/BRCC3	11
MF	GO:0005085	guanyl-nucleotide exchange factor activity	111/7116	214/17697	0.0003415	0.02232	0.01973	RALGDS/ARHGEF18/DENND5A/SH2D3C/C9orf72/RASGEF1A/PLEKHG2/SPATA13/RASGRP2/CYTH4/HPS4/RASGEF1B/ARHGEF3/RASGRP3/DENND1A/ALS2/CYTH1/FGD6/FGD5/DOCK10/AKAP13/RAPGEF6/ARHGEF10L/DENND4A/ARHGEF40/DENND1B/DOCK8/RAPGEF2/SEC61B/ARF4/ARFGEF1/DENND2D/DENND3/RCBTB2/EIF2B5/HPS1/ITSN1/RGL1/ADRB1/TRAPPC5/ABR/NET1/ARHGEF6/RAB3GAP1/LAMTOR1/HERC2/IQSEC1/RASGRP1/RIN2/ARHGEF2/RAP1A/P2RY12/ANKRD27/TAGAP/SH3BP5L/FBXO8/DENND6B/RGL3/KALRN/RPGR/RCC1/FLCN/MYCBP2/DOCK5/DENND4C/BCR/BCAR3/RGL4/FNIP1/SBF1/LAMTOR4/RANGRF/OBSCN/RABGEF1/RASGRF1/LAMTOR5/ELMO1/VAV1/RCC2/DOCK11/IQSEC2/PREX1/ITSN2/RALGPS1/TRAPPC3/CCZ1/SMCR8/EIF2B1/ARHGEF37/IQSEC3/FGD3/DENND5B/ARHGEF17/EIF2B3/KNDC1/FGD4/PSD4/DENND4B/EPS8L2/DENND6A/SBF2/DENND2A/RGP1/GDPGP1/ARHGEF4/EIF2B2/PREB/MCF2L/ARHGEF9/PSD3/RASGRP4	111
MF	GO:0015631	tubulin binding	166/7116	336/17697	0.0003546	0.02232	0.01973	S100A9/S100A8/FYN/EZR/SUN2/DPYSL2/STMN1/LYN/MAP1S/DNM3/SYT11/BLOC1S2/GAPDH/FCHO1/ARL4C/RAB11A/CHP1/RITA1/FCHO2/GAS2L1/RGS2/EML4/ATF5/TTLL4/VPS41/KIF9/PSRC1/MX2/KIF3B/JAKMIP2/CCDC88B/NEIL2/CETN3/MAP1LC3A/MAP4/CLIP1/CENPE/STMN3/EML3/KIFC3/PDE4B/PAFAH1B1/CDK5RAP2/ALDOA/EMD/ARHGEF2/KIF4A/MAPRE1/RABGAP1/SKA2/SPAG5/VAPB/TPPP3/HOOK2/NDRG1/CCDC88A/MAPRE2/KIF2A/DNAL1/CCSER2/LRRK2/PPARGC1A/MAP1LC3C/GPAA1/ZNF207/PDCD5/KRIT1/KIF16B/MAP7D3/BBS4/DIXDC1/ARL8A/GAS2L2/BCL2L11/DNM1/CCDC69/TBCEL/BCCIP/HOOK3/DNM2/BCAS3/RGS14/KIF24/TUBGCP3/NME1/KIF20B/MX1/CKAP5/JAKMIP1/NDEL1/PHF6/GAS2L3/KIF13A/NUSAP1/DNM1L/CACYBP/KIF27/KATNA1/CLASP2/UNC5C/BRCA1/PEX14/TBCC/TUBGCP5/AGBL1/FAM161A/CAPN6/CEP57/VBP1/RCC2/CETN1/CETN2/CAV3/TBCA/MID2/CRIPT/KATNAL1/MAP1A/FMR1/KIF2C/KIF17/SMC3/TPGS1/KATNB1/CLIP2/KIF1B/SKAP1/KIF5B/GABARAPL1/EML6/TRAF3IP1/TBCE/POLB/MAP4K4/KIF1C/NAV3/TRPV4/BRSK1/DAG1/SNCA/CLIP3/TTBK2/KIF12/IFT74/BEX4/EFHC1/FGF13/UXT/CCDC66/AGTPBP1/APPL1/GJA1/KLC3/LZTS1/TTLL6/TPPP/IFT81/RP1/KIF14/MACF1/PRC1/GAS8/DPYSL5/ARL8B/STRBP/FMN1	166
MF	GO:0019887	protein kinase regulator activity	95/7116	180/17697	0.00041	0.02452	0.02167	ITPRIP/FAM20A/RAC2/PRKAR2B/CDKN2D/CDKN1A/SOCS3/CCNL1/CCND3/CHP1/MAP2K1/CIB1/ALS2/RGCC/ELP4/GPRC5B/CXCL10/ERCC6/TESC/CCND2/KAT2B/HEXIM1/CDC37/CDK4/TGFB1/TAOK3/HSPB1/PKIB/GMFG/ETAA1/NRG1/HYAL2/MBIP/CCNG1/DBF4B/DUS2/NCK1/CDKN2B/CASP3/SFN/NPM1/CCNH/PAK2/PARP16/TOM1L1/CCL5/CDKN1C/CSNK2B/ATG13/SH3BP5L/HEXIM2/CCND1/DUSP19/MLST8/DDX3X/PRKAG2/TAB1/CCNE1/ELP3/MARK2/CDKN1B/CDKN2C/CCNK/TRIB2/DAZAP2/CCNL2/MAP2K2/GSKIP/CDK5R2/SPRED1/CCNY/SPRY2/CCNA1/SMCR8/SOCS1/CCNC/CCNYL1/PRKAG1/FGFR1OP/HSP90AB1/CCNA2/YWHAG/PKIA/CCNT1/CCNYL2/CCNG2/CCNB3/FGF13/STRADA/GREM1/DAXX/CD24/ERBB3/GHRL/CCNF	95
MF	GO:0035014	phosphatidylinositol 3-kinase regulator activity	14/7116	17/17697	0.0004786	0.02725	0.02408	KLF4/SOCS3/WDR91/WDR81/CISH/PIK3R3/SOCS5/SOCS6/PIK3R6/SOCS7/SOCS1/SLA2/CCKBR/SOCS2	14
MF	GO:0050786	RAGE receptor binding	10/7116	11/17697	0.0007686	0.04179	0.03692	S100A9/S100A8/S100A12/FPR1/S100P/S100B/S100A4/HMGB1/S100A13/HMGB2	10
MF	GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	28/7116	43/17697	0.0008336	0.04335	0.03831	ALDH3A2/AKR1B1/ALDH9A1/FAR2/GAPDH/ALDH1A1/ALDH7A1/ADH5/ALDH6A1/AKR1C3/ALDH18A1/ALDH2/OGDH/ALDH4A1/ALDH5A1/DHTKD1/ALDH8A1/PDHB/FAR1/AKR1B10/DLAT/PDHA2/BCKDHB/ALDH1L1/BCKDHA/AOX1/ALDH3A1/ADH7	28
MF	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	31/7116	49/17697	0.0009226	0.04598	0.04063	CDKN2D/CDKN1A/CCNL1/CCND3/CCND2/KAT2B/HEXIM1/CDK4/CCNG1/CDKN2B/CASP3/CCNH/CDKN1C/HEXIM2/CCND1/CCNE1/CDKN1B/CDKN2C/CCNK/CCNL2/CDK5R2/CCNY/CCNA1/CCNC/CCNYL1/CCNA2/CCNT1/CCNYL2/CCNG2/CCNB3/CCNF	31
MF	GO:0004860	protein kinase inhibitor activity	38/7116	63/17697	0.0009816	0.04696	0.04149	ITPRIP/PRKAR2B/CDKN2D/CDKN1A/SOCS3/CHP1/CIB1/TESC/KAT2B/HEXIM1/TAOK3/HSPB1/PKIB/GMFG/HYAL2/MBIP/DUS2/NCK1/CDKN2B/CASP3/SFN/NPM1/CDKN1C/SH3BP5L/HEXIM2/DUSP19/PRKAG2/CDKN1B/CDKN2C/TRIB2/GSKIP/SPRED1/SPRY2/SMCR8/SOCS1/FGFR1OP/YWHAG/PKIA	38
MF	GO:0030695	GTPase regulator activity	149/7116	304/17697	0.001056	0.04856	0.04291	HTR2B/SIPA1L1/TBC1D24/RALGDS/CDC42SE1/ARHGAP31/STARD8/VPS9D1/ARAP1/MYO9B/ARAP3/ALDH1A1/ADPRH/STARD13/RGS2/RASGRP3/RABGAP1L/AGFG1/RGS1/STXBP5/TBC1D15/ARHGDIA/FAM13A/IQGAP2/ARHGEF10L/ASAP2/ARHGAP27/TBC1D5/SH3BP4/ELMOD2/ARHGAP30/CDC42EP2/ARHGAP20/ARRB1/ARHGAP25/GNAQ/RAPGEF2/SGSM1/TBC1D1/ARHGAP19/ABR/ARHGDIB/RASA2/ARHGAP22/ARHGEF6/SRGAP3/OPHN1/RGS12/RAB3GAP1/ARFGAP3/GDI1/RP2/ARHGAP26/GDI2/RIN2/RASAL3/TBC1D2/ANKRD27/TAGAP/RABGAP1/NPRL3/TBCK/SH3BP1/AGAP4/GPSM1/ARHGAP24/OCRL/LRRK2/PDE6D/FLCN/DOCK5/TBC1D12/KRIT1/ARHGAP6/BCR/ARHGAP12/RALGAPB/RGS3/SRGAP2/RASA3/TBC1D17/GPSM3/NRP1/TBC1D9B/TBC1D20/TBC1D13/RGS14/TBC1D8/SIPA1L3/ARHGAP18/ACAP1/SYNGAP1/TBC1D8B/RGS5/TBC1D7/EIF5/TBC1D22A/DNM1L/RHOH/GARNL3/PLCB1/RABEP1/GMIP/GPSM2/PREX1/SLIT2/RALBP1/IPO7/RUNDC1/NPRL2/RASAL1/ADAP1/TBC1D21/RGS20/NUP50/EVI5/LLGL1/TBC1D10C/RALGAPA2/RIN1/ACAP3/AGAP3/RGS6/AGAP1/ALS2CL/CHN2/SRGAP1/GPS1/ACAP2/DEPDC5/CHM/ITGB1BP1/GRTP1/RGS16/SIPA1L2/ARL2BP/ADAP2/ASAP1/RGS17/RUNDC3A/WAS/SYDE1/PREB/ASAP3/SESN2/SMAP2/ARFGAP1/TBC1D10B/CPEB2	149
MF	GO:0001608	G protein-coupled nucleotide receptor activity	11/7116	13/17697	0.00138	0.05895	0.05209	P2RY14/P2RY8/PTAFR/P2RY6/GPR171/P2RY12/GPR34/P2RY13/P2RY4/P2RY10/P2RY1	11
MF	GO:0045028	G protein-coupled purinergic nucleotide receptor activity	11/7116	13/17697	0.00138	0.05895	0.05209	P2RY14/P2RY8/PTAFR/P2RY6/GPR171/P2RY12/GPR34/P2RY13/P2RY4/P2RY10/P2RY1	11
MF	GO:0030145	manganese ion binding	37/7116	62/17697	0.001501	0.06189	0.05468	EXTL2/ARG2/PIM1/MGAT2/LAP3/TDP2/MGAT5/HMGCL/ME1/PEPD/DYRK2/PCK2/ABL1/MPPED2/XPNPEP1/DCP2/CDIPT/PPM1M/PAPOLA/MTPAP/XYLT2/PPM1N/MPPE1/PRKACA/MGAT5B/NUDT7/ABL2/XXYLT1/PPEF2/XPNPEP3/B4GALT1/GALNT1/NPEPL1/NEK4/NUDT16/FEN1/IMPA1	37
MF	GO:0019787	ubiquitin-like protein transferase activity	193/7116	407/17697	0.001693	0.06227	0.05503	KLHL21/TRIM32/KLHL13/HLTF/WWP1/ATG3/BARD1/RNF103/ZBED1/RNF41/SH3RF1/WDSUB1/ZFP91/TNFAIP3/PEX12/FBXO6/HECTD3/RNF10/BIRC2/SIAH1/FBXO30/UBE2Z/RNF111/RNF139/RNF149/TRIM23/MED10/UBE2N/UHRF1/RNF145/SKP2/MED11/TRIM13/UBE2Q2/RNF19B/FBXL5/FBXW2/TMEM129/TRIM68/MIB1/UBE4B/TRIM37/UBE3A/UBE2K/ZNF451/RNF138/CBLB/UBE2S/KCTD10/UFC1/FEM1B/TRIM47/UBE2D3/RNF170/RBBP6/IRF2BP1/DTX4/TRAF6/RNF217/RNF175/FBXL20/RNF13/TRAF3/UBE2D2/UBE2L6/ANKIB1/HERC2/NSMCE2/RNF11/UBR5/UBE2J1/UBE2W/UBE2E1/RNF146/RNF113A/UBE2A/MED27/FBXL18/FBXL4/UBE2F/RBCK1/TRIM11/EGR2/UBE2G2/NHLRC3/RNF213/CDC23/RNF115/BCOR/UHRF2/MYCBP2/CBLL1/FBXL3/RNF7/HERC6/ANAPC5/KLHL9/RNFT1/DTX3L/ARIH2/TRIM24/UBE2E2/TRIM21/NEDD4/UBE2D4/HDAC4/RFWD3/RNF126/KCMF1/BIRC3/UBR3/CNOT4/RNF24/CBX4/SH3RF3/RFFL/G2E3/RABGEF1/UBE2C/BIRC7/MED30/RING1/GID4/STUB1/DTL/RNF20/HACE1/PIAS3/FANCL/FBXO4/PDZD4/BRCA1/MUL1/WWP2/PPP1R11/TRAF2/TRIM33/BFAR/RNF43/UBE2M/MDM2/HERC5/FBXL6/DDB2/UBR1/FBXL2/HERC4/ANAPC4/SHPRH/RNF212B/RNF214/FBXL7/ZNRF1/FBXO27/RNF4/UBE2I/ZSWIM2/FBXO44/ZNRF4/RNF185/LRRC29/RNF5/PRPF19/FBXO25/RNF208/UBE2G1/TRIM6/FBXL17/ASB1/FBXL14/TOPORS/ANAPC11/RNF167/RNF216/RBX1/KLHL42/RLIM/MALT1/XIAP/PDZRN4/TRIM58/CHFR/UBE2B/PELI2/FBXL12/UBL4A/KIAA1586/UBE3B/FBXL16/SIAH2/RNF135/ZNRF2/ERCC8	193
MF	GO:0001614	purinergic nucleotide receptor activity	15/7116	20/17697	0.001707	0.06227	0.05503	P2RY14/P2RY8/P2RX7/PTAFR/P2RY6/GPR171/P2RY12/GPR34/P2RX1/P2RY13/P2RY4/P2RY10/P2RX2/P2RY1/P2RX5	15
MF	GO:0016502	nucleotide receptor activity	15/7116	20/17697	0.001707	0.06227	0.05503	P2RY14/P2RY8/P2RX7/PTAFR/P2RY6/GPR171/P2RY12/GPR34/P2RX1/P2RY13/P2RY4/P2RY10/P2RX2/P2RY1/P2RX5	15
MF	GO:0071723	lipopeptide binding	9/7116	10/17697	0.001749	0.06227	0.05503	TLR1/TLR2/CD1C/CD1E/CD1B/CD1D/CD1A/LBP/TLR6	9
MF	GO:0001882	nucleoside binding	185/7116	389/17697	0.00177	0.06227	0.05503	PNP/RAB9A/RAC2/RAB42/GBP2/GCH1/TUBA1A/ARF6/DNM3/ARL4A/GBP1/RAP1B/RHOBTB1/GNAI3/ARL4C/RAB11A/TUBB6/RHOC/GNA15/DYNC1LI1/ACTN4/GNL2/TRIM23/ACSM5/RRAS/GIMAP6/GBP5/NKIRAS1/RAN/KRAS/AK3/RAB31/RND3/TSR1/TUBB2A/MX2/URGCP/MIEF1/NKIRAS2/RAB23/GTPBP4/SAR1B/GNAQ/ARF4/PCK2/GBP4/ARL13B/ATL1/INSR/RAP2C/RAB24/MTIF2/RHOG/ARF5/EHD4/HRAS/SPAG1/GIMAP4/TUBB3/MPPED2/RP2/RAP2B/GUF1/RHOT2/SAMHD1/TUBD1/RAP1A/RAB20/DAPK1/RRAGD/EHD1/RAB8A/RAB43/MFHAS1/RAC1/GLUD1/RAB33B/RAB29/IFI44L/LRRK2/RAB32/FPGT/GPN1/NOLC1/RAB38/RHOU/RNGTT/SAR1A/GSPT2/MTPAP/ARF1/GLUD2/ARL8A/DNM1/NMUR2/ANXA6/RIT1/GTPBP1/ATL3/IRGQ/DNM2/GNAI2/TUBA1C/TGM2/LSG1/RAB5C/RAB39B/TUBA4B/HHAT/RHOQ/NME1/MX1/NRAS/RAB5A/GFM2/TUBA4A/RHOV/RASL12/EIF5/RASL11A/ARL1/NOA1/ARFRP1/RASL11B/RHOF/ARL14/RAB7B/RRAGA/ADA/SUCLG2/DNM1L/RHOH/EEF1A2/DAP3/TUBG2/RAB8B/TUBB4A/RAB22A/RAB3A/GNA13/TUBAL3/RAB35/GUCY2D/TUBB1/TUBA1B/ARL4D/ARL15/RHOBTB3/GNL3L/GBP6/DIRAS1/EHD3/RAB3B/IFT22/HSP90AB1/AGAP3/POLA1/REM2/AGAP1/CDA/ARL10/RHOA/SCG5/RAB33A/RAB3D/GFM1/RABL6/GTPBP3/GIMAP7/EIF2B2/NUDT16/RHOBTB2/EFTUD2/GNL3/LANCL2/OARD1/ARF3/RASL10A/RAB27A/RAB26/RAB36/RASD2/GNA11/ARL8B/RAB28	185
MF	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	12/7116	15/17697	0.002026	0.06371	0.0563	LPCAT2/MBOAT7/LPGAT1/PNPLA3/AGPAT3/AGPAT4/CRLS1/MBOAT2/AGPAT5/AGPAT1/TAZ/AGPAT2	12
MF	GO:0005092	GDP-dissociation inhibitor activity	12/7116	15/17697	0.002026	0.06371	0.0563	ARHGDIA/SH3BP4/ARHGDIB/GDI1/GDI2/GPSM1/RGS14/EIF5/GPSM2/CHM/ITGB1BP1/SESN2	12
MF	GO:0042171	lysophosphatidic acid acyltransferase activity	12/7116	15/17697	0.002026	0.06371	0.0563	LPCAT2/MBOAT7/LPGAT1/PNPLA3/AGPAT3/AGPAT4/CRLS1/MBOAT2/AGPAT5/AGPAT1/TAZ/AGPAT2	12
MF	GO:0032182	ubiquitin-like protein binding	53/7116	96/17697	0.002051	0.06371	0.0563	TRIM32/NUP62/TNFAIP3/BIRC2/FBXW7/RNF111/UCHL1/SQSTM1/UBE2N/RAD23B/PLAA/RNF19B/DCUN1D1/HSPB1/UBXN7/IKBKG/HABP4/TP53INP2/UBXN2B/UBE2L6/HERC2/TOM1L1/NSFL1C/ADRM1/UBR5/PML/SIMC1/RBCK1/TDG/RNFT1/BUB3/NPLOC4/UBA2/USP16/DCUN1D5/WDR92/NEDD4/TSG101/TOLLIP/UBAP1/USPL1/CBX4/MDM2/DCUN1D3/UBAP1L/UBXN1/RNF4/RNF185/DCUN1D4/NBR1/DAXX/UBXN11/TOP2A	53
MF	GO:0070491	repressing transcription factor binding	41/7116	71/17697	0.002078	0.06371	0.0563	SKI/RBPJ/BBS5/STAT3/PPARD/DDX20/DDRGK1/STAT1/TTC8/MYC/CBX5/GMNN/BBS10/RELA/SIN3A/TLE1/MTA3/TLE4/MIER1/HMGB1/BBS2/MKKS/SRI/BBS4/HDAC2/KAT5/HDAC7/ZNF703/NOC2L/HDAC4/TLE6/BBS7/PPARA/GTF2A1/TCF7L2/EIF4E/ARNTL/TBP/HDAC5/MTA2/ZMYND8	41
MF	GO:0019210	kinase inhibitor activity	39/7116	67/17697	0.002163	0.06468	0.05716	ITPRIP/PRKAR2B/CDKN2D/CDKN1A/SOCS3/CHP1/CIB1/TESC/KAT2B/HEXIM1/TAOK3/HSPB1/PKIB/GMFG/HYAL2/MBIP/DUS2/NCK1/CDKN2B/CASP3/SFN/NPM1/CDKN1C/SH3BP5L/HEXIM2/DUSP19/PRKAG2/CDKN1B/CDKN2C/TRIB2/GSKIP/RHOH/SPRED1/SPRY2/SMCR8/SOCS1/FGFR1OP/YWHAG/PKIA	39
MF	GO:0019865	immunoglobulin binding	17/7116	24/17697	0.002343	0.06721	0.05939	FCGR1B/PIP/FCGR1A/FCGRT/FCGR3B/LILRA2/FCAR/CD22/FCGR2C/FCER1A/FCER2/MS4A1/AMBP/VWF/HRG/CD4/FCGR2A	17
MF	GO:0003743	translation initiation factor activity	31/7116	51/17697	0.00236	0.06721	0.05939	EIF1/AGO2/EIF1B/EIF6/EIF4E3/MTIF2/EIF2D/EIF2B5/EIF3M/EIF4B/EIF3I/EIF2S2/EIF4E2/EIF4H/EIF2S1/EIF4G2/EIF3G/MCTS1/EIF4G3/EIF3B/EIF5/EIF3J/MTIF3/EIF4G1/EIF2B1/EIF2A/EIF4E/EIF2B3/EIF3L/EIF2B2/EIF1AX	31
MF	GO:0050662	coenzyme binding	141/7116	291/17697	0.002471	0.06873	0.06073	GCH1/LDHA/POR/HIBADH/AIFM1/CBR4/MDH1/TPMT/SRD5A1/GAPDH/STEAP4/HADH/HMGCL/ALDH1A1/SIRT4/CYB5R1/AHCY/ACOT7/CRYL1/KDM1B/PHYH/PHYKPL/SQLE/ME1/CTBP2/SOAT1/AIFM2/ALDH6A1/GSR/FMO4/SCP2/HMGCR/TXNRD1/MICAL1/PNPLA3/SUV39H2/ETFA/NFS1/SGPL1/HPGD/PANK3/METTL3/ACADM/DBT/ACADS/PANK1/DECR1/NUDT6/MICAL2/QSOX1/DUS2/SPTLC2/EGLN1/CAT/MTRR/GCLC/DPYD/SIRT7/AGPS/FOXRED2/ALDH2/ME3/ACOX1/ETFDH/ECI2/QDPR/ACACB/OGDH/IDH1/ACOX2/SIRT1/ACBD5/ACADSB/GLUD1/LDHB/G6PD/BDH2/PLOD1/DAO/EGLN3/IDH2/MCCC1/TM7SF2/KYNU/SPR/DHTKD1/WWOX/SHMT2/PAM/OGFOD2/MMACHC/SIRT5/CBR3/SUOX/CTH/PLOD2/ACBD3/KCNAB1/ACBD4/COQ6/CYBB/SORD/ACADVL/CYB5R3/GOT2/HADHA/AGXT2/SHMT1/DHFR/IDH3A/MAOB/DBI/ACOX3/SRR/ALAS1/PYGM/PGD/SDHA/DBH/PYGL/MTO1/PC/MARC2/GRHPR/ME2/IDH3G/FMO2/DUS1L/CRYZ/GMDS/CHDH/PRMT1/AOX1/PHGDH/HACL1/NNT/P4HA1/NDUFS2/GLYR1/HAO1/ALB	141
MF	GO:0003779	actin binding	202/7116	431/17697	0.002662	0.07189	0.06352	MYO1G/NOD2/PIP/VASP/EZR/PLS1/MAP1S/FHOD1/GBP1/FMNL3/FMNL1/MARCKSL1/DIAPH1/PDLIM1/MYO9B/ENC1/PLEC/FLNA/SSH2/MLPH/FHL3/ACTN4/YWHAH/PSTPIP1/TPM3/VCL/TMSB10/SPIRE1/STK38L/FXYD5/IQGAP2/COBLL1/ACTR2/MICAL1/TMOD3/LIMA1/HCLS1/GAS7/BCL7B/EVL/TWF2/TLN1/RDX/PHACTR2/DAAM1/PFN1/PARVB/CTNNA1/EPB41L1/VASH1/MARCKS/PHACTR1/CFL2/MYO5A/CAPZA2/PANX1/PDLIM7/ACTN1/GMFG/CORO1A/CAPG/MICAL2/CAP1/DIAPH2/TNNI2/SVIL/PSTPIP2/ABL1/TAGLN/OPHN1/MYBPC3/ALDOA/EMD/ALKBH4/CTNNAL1/AIF1/NEXN/ARPC1A/CAPZA1/S100A4/BLOC1S6/DMD/MED28/DNASE1/SPTBN1/CCDC88A/ARPC1B/KPTN/LRRK2/CLMN/CYFIP1/MYO1C/SNTB1/CCR5/CORO1B/PTK2/MYH9/LIMCH1/DIXDC1/CNN2/SYNE2/TPM4/MYO5C/PDLIM5/CTNNA3/ARPC5L/LCP1/CORO2A/ABLIM3/WIPF2/FSCN3/ANXA6/COTL1/MEFV/VPS18/TMEM201/TPM1/PPP1R18/AVIL/ERMN/MICALL2/PLS3/TLN2/TNNC2/CFL1/IPP/TRIOBP/ADD3/GAS2L3/JMY/ACTR3B/GCSAM/DMTN/CORO1C/ACTR3/IMPACT/CDK5R2/LASP1/FLNB/MYOZ1/MSRB1/MYLK/LMOD3/EGFR/ABL2/SCIN/MYOM2/FSCN1/MAP1A/FLII/EPB41/MSN/INF2/ARPC4/MYO10/TBC1D21/SNTB2/KLHL5/PXK/SPTA1/SSH3/SPTBN2/PHACTR4/SYNPO2L/FGD4/FBXO25/MYH2/ENAH/VPS16/WIPF1/EPB41L2/ARPC2/SNTA1/EPS8L2/RUSC1/MISP/CAP2/KCNMA1/TRPV4/PICK1/DAG1/SNCA/PDLIM4/MYO15A/SSH1/SHROOM1/TULP1/MYH3/MTSS1/ESPNL/WAS/INPPL1/SHANK3/DAAM2/SPATA32/BIN1/MACF1/MYOZ3/CAMK2B/SYNPO/ABLIM1/FMN1	202
MF	GO:0009055	electron transfer activity	61/7116	114/17697	0.002705	0.07189	0.06352	NQO1/C15orf48/POR/SRD5A1/AKR1B1/STEAP4/SH3BGRL3/COX11/ADH5/ME1/UQCR11/DEGS1/AIFM2/GSR/TXNRD1/AKR7A2/ETFA/DHRS3/AKR7A3/AKR1A1/DHDH/CYB5A/RDH16/NCF2/NDUFS3/NCF1/LOXL2/IDO1/ALDH2/ETFDH/QDPR/ALDH4A1/UQCR10/COX7C/HAAO/COX7A2L/NDUFA4/GLRX3/COX4I2/CYP1A2/ETFB/COX15/CYBA/CYBB/UQCRQ/FDX1/NDUFS1/MAOB/SURF1/SDHA/NDUFAF2/NDUFV2/SDHD/ME2/UQCRB/COX6C/AOX1/PHGDH/NDUFS2/CIAPIN1/COX7B	61
MF	GO:0004722	protein serine/threonine phosphatase activity	43/7116	76/17697	0.00281	0.07261	0.06416	DUSP1/PPP2CA/PPM1H/PALD1/SHOC2/PPP4C/PPP3CB/PPP1R3D/PPM1D/PPA2/PPM1F/CTDP1/PPM1M/LCK/PPP6C/DUSP4/DUSP23/CTDSPL/PPM1N/TAB1/PPP2R2D/MTMR4/PPP2R2B/MTMR6/CTDSP1/PPM1L/PPP4R1/PPM1J/PPP1CC/PPP1CA/PPP2R1B/PDP2/CTDSP2/MTMR3/PPEF2/RPAP2/PDP1/PPP1CB/PHLPP2/TIMM50/MYH3/PPM1G/PPP2R2C	43
MF	GO:0001883	purine nucleoside binding	180/7116	381/17697	0.00289	0.07261	0.06416	RAB9A/RAC2/RAB42/GBP2/GCH1/TUBA1A/ARF6/DNM3/ARL4A/GBP1/RAP1B/RHOBTB1/GNAI3/ARL4C/RAB11A/TUBB6/RHOC/GNA15/DYNC1LI1/GNL2/TRIM23/ACSM5/RRAS/GIMAP6/GBP5/NKIRAS1/RAN/KRAS/AK3/RAB31/RND3/TSR1/TUBB2A/MX2/URGCP/MIEF1/NKIRAS2/RAB23/GTPBP4/SAR1B/GNAQ/ARF4/PCK2/GBP4/ARL13B/ATL1/INSR/RAP2C/RAB24/MTIF2/RHOG/ARF5/EHD4/HRAS/SPAG1/GIMAP4/TUBB3/MPPED2/RP2/RAP2B/GUF1/RHOT2/SAMHD1/TUBD1/RAP1A/RAB20/DAPK1/RRAGD/EHD1/RAB8A/RAB43/MFHAS1/RAC1/GLUD1/RAB33B/RAB29/IFI44L/LRRK2/RAB32/FPGT/GPN1/NOLC1/RAB38/RHOU/RNGTT/SAR1A/GSPT2/ARF1/GLUD2/ARL8A/DNM1/NMUR2/ANXA6/RIT1/GTPBP1/ATL3/IRGQ/DNM2/GNAI2/TUBA1C/TGM2/LSG1/RAB5C/RAB39B/TUBA4B/HHAT/RHOQ/NME1/MX1/NRAS/RAB5A/GFM2/TUBA4A/RHOV/RASL12/EIF5/RASL11A/ARL1/NOA1/ARFRP1/RASL11B/RHOF/ARL14/RAB7B/RRAGA/ADA/SUCLG2/DNM1L/RHOH/EEF1A2/DAP3/TUBG2/RAB8B/TUBB4A/RAB22A/RAB3A/GNA13/TUBAL3/RAB35/GUCY2D/TUBB1/TUBA1B/ARL4D/ARL15/RHOBTB3/GNL3L/GBP6/DIRAS1/EHD3/RAB3B/IFT22/HSP90AB1/AGAP3/REM2/AGAP1/ARL10/RHOA/SCG5/RAB33A/RAB3D/GFM1/RABL6/GTPBP3/GIMAP7/EIF2B2/NUDT16/RHOBTB2/EFTUD2/GNL3/LANCL2/OARD1/ARF3/RASL10A/RAB27A/RAB26/RAB36/RASD2/GNA11/ARL8B/RAB28	180
MF	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	10/7116	12/17697	0.002935	0.07261	0.06416	CDKN2D/CDKN1A/KAT2B/HEXIM1/CDKN2B/CASP3/CDKN1C/HEXIM2/CDKN1B/CDKN2C	10
MF	GO:0003924	GTPase activity	155/7116	324/17697	0.002975	0.07261	0.06416	RAB9A/RAC2/RAB42/GBP2/GCH1/TUBA1A/ARF6/DNM3/GBP1/RAP1B/RHOBTB1/GNAI3/ARL4C/RAB11A/TUBB6/GNB1/GNB2/RHOC/GNA15/RGS2/GNL2/GNG5/RGS1/TRIM23/RRAS/GBP5/NKIRAS1/RAN/KRAS/RAB31/RND3/TSR1/GNG7/TUBB2A/MX2/NKIRAS2/RAB23/GTPBP4/SAR1B/NUDT1/GNAQ/ARF4/GBP4/ATL1/RAP2C/RAB24/MTIF2/RHOG/ARF5/ARHGDIB/HRAS/TUBB3/RGS12/RAP2B/GUF1/RHOT2/TUBD1/RAP1A/RAB20/RRAGD/RAB8A/RGS19/RAB43/RAC1/RAB33B/RAB29/LRRK2/GNG2/RAB32/GPN1/RAB38/RHOU/GNB3/DDX3X/SAR1A/GSPT2/ARF1/RGS3/ARL8A/DNM1/RIT1/GTPBP1/ATL3/DNM2/GNAI2/TUBA1C/LSG1/RAB5C/RAB39B/TUBA4B/RGS14/RHOQ/MX1/NRAS/RAB5A/GFM2/TUBA4A/RHOV/RGS5/RASL12/EIF5/RASL11A/ARL1/ARFRP1/RASL11B/RHOF/RAB7B/RRAGA/DNM1L/RHOH/EEF1A2/TUBG2/RAB8B/TBCC/TUBB4A/RAB22A/RAB3A/GNA13/TUBAL3/RAB35/TUBB1/TUBA1B/GNG11/ARL4D/RGS20/RHOBTB3/GBP6/DIRAS1/RAB3B/IFT22/GNG12/AGAP3/RGS13/REM2/RGS6/AGAP1/RHOA/RAB33A/RAB3D/RGS16/GFM1/GTPBP3/GIMAP7/RGS17/RHOBTB2/EFTUD2/ARF3/RASL10A/RAB27A/RAB26/RAB36/RASD2/GNA11/ARL8B/RAB28	155
MF	GO:0051087	chaperone binding	55/7116	102/17697	0.003426	0.08121	0.07176	FN1/GRN/TSC1/SOD1/ATP1A1/ERP29/CDC37L1/BIRC2/CTSC/DNAJA4/CDC37/DNAJB1/HSPA5/DNAJB5/CLU/GRPEL1/SDF2L1/DNAJC1/DNAJB6/PTGES3/DNAJB4/GRPEL2/FNIP1/BAX/CDKN1B/PFDN4/CDC25A/DNAJC10/GET4/VWF/HES1/DNAJB9/STUB1/CALR/TBCC/TBCA/TSACC/BAG2/PIH1D3/HSCB/ATP7A/DNAJA1/HYOU1/HSPB6/TERT/TBCE/BAG5/ST13/BAK1/ATP1A2/UBL4A/BIN1/TIMM44/ALB/TIMM9	55
MF	GO:0017112	Rab guanyl-nucleotide exchange factor activity	24/7116	38/17697	0.003547	0.08121	0.07176	DENND5A/C9orf72/DENND1A/ALS2/DENND4A/DENND1B/DENND2D/DENND3/TRAPPC5/RAB3GAP1/RIN2/SH3BP5L/DENND6B/DENND4C/SBF1/RABGEF1/TRAPPC3/SMCR8/DENND5B/DENND4B/DENND6A/SBF2/DENND2A/RGP1	24
MF	GO:0043531	ADP binding	24/7116	38/17697	0.003547	0.08121	0.07176	PGK1/ATP1A1/MYO9B/TAP1/ME1/PKM/MIEF1/RUVBL2/RUVBL1/GCLC/GLUD1/MYH9/GLUD2/PRKAG2/ABCG1/CYB5R3/PGK2/CHORDC1/PRKAG1/VCP/ERN1/ABCD1/ACTA1/P2RY1	24
MF	GO:0032550	purine ribonucleoside binding	178/7116	378/17697	0.003599	0.08121	0.07176	RAB9A/RAC2/RAB42/GBP2/GCH1/TUBA1A/ARF6/DNM3/ARL4A/GBP1/RAP1B/RHOBTB1/GNAI3/ARL4C/RAB11A/TUBB6/RHOC/GNA15/DYNC1LI1/GNL2/TRIM23/ACSM5/RRAS/GIMAP6/GBP5/NKIRAS1/RAN/KRAS/AK3/RAB31/RND3/TSR1/TUBB2A/MX2/URGCP/MIEF1/NKIRAS2/RAB23/GTPBP4/SAR1B/GNAQ/ARF4/PCK2/GBP4/ARL13B/ATL1/INSR/RAP2C/RAB24/MTIF2/RHOG/ARF5/EHD4/HRAS/SPAG1/GIMAP4/TUBB3/MPPED2/RP2/RAP2B/GUF1/RHOT2/SAMHD1/TUBD1/RAP1A/RAB20/DAPK1/RRAGD/EHD1/RAB8A/RAB43/MFHAS1/RAC1/GLUD1/RAB33B/RAB29/IFI44L/LRRK2/RAB32/FPGT/GPN1/NOLC1/RAB38/RHOU/RNGTT/SAR1A/GSPT2/ARF1/GLUD2/ARL8A/DNM1/NMUR2/ANXA6/RIT1/GTPBP1/ATL3/IRGQ/DNM2/GNAI2/TUBA1C/TGM2/LSG1/RAB5C/RAB39B/TUBA4B/HHAT/RHOQ/NME1/MX1/NRAS/RAB5A/GFM2/TUBA4A/RHOV/RASL12/EIF5/RASL11A/ARL1/NOA1/ARFRP1/RASL11B/RHOF/ARL14/RAB7B/RRAGA/SUCLG2/DNM1L/RHOH/EEF1A2/DAP3/TUBG2/RAB8B/TUBB4A/RAB22A/RAB3A/GNA13/TUBAL3/RAB35/GUCY2D/TUBB1/TUBA1B/ARL4D/ARL15/RHOBTB3/GNL3L/GBP6/DIRAS1/EHD3/RAB3B/IFT22/HSP90AB1/AGAP3/REM2/AGAP1/ARL10/RHOA/SCG5/RAB33A/RAB3D/GFM1/RABL6/GTPBP3/GIMAP7/EIF2B2/NUDT16/RHOBTB2/EFTUD2/GNL3/LANCL2/ARF3/RASL10A/RAB27A/RAB26/RAB36/RASD2/GNA11/ARL8B/RAB28	178
MF	GO:0005543	phospholipid binding	199/7116	427/17697	0.003883	0.08601	0.076	NRGN/MYOF/MYO1G/ZFYVE26/ANXA1/APPL2/SNX1/WNT5A/SYT11/BBS5/ARAP1/NUP62/TPCN1/DGKA/FCHO1/ARAP3/PLEKHA1/RPS6KC1/PACSIN2/FCHO2/SNX10/ESYT2/PITPNA/DENND1A/PAFAH2/APOC1/SCARB1/PLA2G7/PSAP/PXDC1/C2CD5/SLC9A1/RAPGEF6/PIGK/SH3PXD2A/PEBP1/CETP/IQGAP2/APOE/GRK5/ANXA3/PLD1/PNPLA3/DENND1B/AXL/TWF2/TLN1/PLEK2/EXOC1/TULP3/OSBPL1A/ITPR1/PFN1/UNC13B/PTAFR/MAP1LC3A/RAPGEF2/ZFYVE28/NCF4/CPNE8/PITPNM1/MICALL1/PLEKHB2/DAPP1/ANXA9/SNX20/NCF1/SNX18/ZCCHC2/RASA2/OPHN1/ABCA1/PLA2G15/ARHGAP26/NSFL1C/RASGRP1/C2CD2L/SDCBP/CD300LF/SHC1/MARK1/KCNJ1/HMGB1/WIPI1/ATP8B1/DOC2B/NISCH/SPTBN1/CCDC88A/SNX33/CLVS2/GPAA1/SH3YL1/SYT6/SNX27/APOA5/KRIT1/BIN2/HS1BP3/SNX30/KIF16B/SNX6/NME4/PLEKHA8/ZFYVE1/ANXA6/GOLPH3L/MPPE1/CHMP2A/ABCG1/TEC/LPAR3/SYTL4/SNX13/WDR45B/KCNQ1/CD300A/OSBPL2/GRB7/PLEK/WDFY1/OBSCN/LPAR1/GOT2/CPTP/UCP1/SNX7/PLCD1/COMMD1/LAPTM4B/PLCB1/SYT13/SCIN/PREX1/ANXA2P2/PLEKHA5/PLD2/CPNE1/SNX5/RAB35/PLEKHA3/APOA1/EPB41/BAD/SYT9/TREM2/SYTL2/MYO10/RASAL1/ADAP1/SNX21/PXK/OGT/GSDMC/CPNE3/SNX19/SYT1/CPNE9/GPR12/MAPKAP1/SPTBN2/FZD7/SNX4/SYT2/PSD4/F3/DOC2A/AGAP1/SYT4/SYT5/MREG/ANXA2/SBF2/CPNE2/PICK1/SNCA/ACAP2/SNX9/TIRAP/TULP1/ADAP2/AIDA/ASAP1/AMER3/SNX16/PICALM/APPL1/LANCL2/GLTP/ZFYVE19/MCF2L/BIN1/FCHSD2/PLEKHA8P1/AMPH/PACSIN3/PLEKHN1/SNX32/SNX17	199
MF	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity	11/7116	14/17697	0.004088	0.0889	0.07856	SOCS3/CISH/PIK3R3/SOCS5/SOCS6/PIK3R6/SOCS7/SOCS1/SLA2/CCKBR/SOCS2	11
MF	GO:0004842	ubiquitin-protein transferase activity	179/7116	382/17697	0.004519	0.09461	0.0836	KLHL21/TRIM32/KLHL13/HLTF/WWP1/BARD1/RNF103/RNF41/SH3RF1/WDSUB1/ZFP91/TNFAIP3/PEX12/FBXO6/HECTD3/RNF10/BIRC2/SIAH1/FBXO30/UBE2Z/RNF111/RNF139/RNF149/TRIM23/MED10/UBE2N/UHRF1/RNF145/SKP2/MED11/TRIM13/UBE2Q2/RNF19B/FBXL5/FBXW2/TMEM129/TRIM68/MIB1/UBE4B/TRIM37/UBE3A/UBE2K/RNF138/CBLB/UBE2S/KCTD10/FEM1B/TRIM47/UBE2D3/RNF170/RBBP6/IRF2BP1/DTX4/TRAF6/RNF217/RNF175/FBXL20/RNF13/TRAF3/UBE2D2/UBE2L6/ANKIB1/HERC2/RNF11/UBR5/UBE2J1/UBE2W/UBE2E1/RNF146/RNF113A/UBE2A/MED27/FBXL18/FBXL4/RBCK1/TRIM11/UBE2G2/NHLRC3/RNF213/CDC23/RNF115/BCOR/UHRF2/MYCBP2/CBLL1/FBXL3/RNF7/HERC6/ANAPC5/KLHL9/RNFT1/DTX3L/ARIH2/TRIM24/UBE2E2/TRIM21/NEDD4/UBE2D4/RFWD3/RNF126/KCMF1/BIRC3/UBR3/CNOT4/RNF24/SH3RF3/RFFL/G2E3/RABGEF1/UBE2C/BIRC7/MED30/RING1/GID4/STUB1/DTL/RNF20/HACE1/FANCL/FBXO4/PDZD4/BRCA1/MUL1/WWP2/PPP1R11/TRAF2/TRIM33/BFAR/RNF43/UBE2M/MDM2/HERC5/FBXL6/DDB2/UBR1/FBXL2/HERC4/ANAPC4/SHPRH/RNF214/FBXL7/ZNRF1/FBXO27/RNF4/ZSWIM2/FBXO44/ZNRF4/RNF185/LRRC29/RNF5/PRPF19/FBXO25/RNF208/UBE2G1/TRIM6/FBXL17/ASB1/FBXL14/TOPORS/ANAPC11/RNF167/RNF216/RBX1/KLHL42/RLIM/MALT1/XIAP/PDZRN4/TRIM58/CHFR/UBE2B/PELI2/FBXL12/UBE3B/FBXL16/SIAH2/RNF135/ZNRF2/ERCC8	179
MF	GO:0032549	ribonucleoside binding	179/7116	382/17697	0.004519	0.09461	0.0836	RAB9A/RAC2/RAB42/GBP2/GCH1/TUBA1A/ARF6/DNM3/ARL4A/GBP1/RAP1B/RHOBTB1/GNAI3/ARL4C/RAB11A/TUBB6/RHOC/GNA15/DYNC1LI1/GNL2/TRIM23/ACSM5/RRAS/GIMAP6/GBP5/NKIRAS1/RAN/KRAS/AK3/RAB31/RND3/TSR1/TUBB2A/MX2/URGCP/MIEF1/NKIRAS2/RAB23/GTPBP4/SAR1B/GNAQ/ARF4/PCK2/GBP4/ARL13B/ATL1/INSR/RAP2C/RAB24/MTIF2/RHOG/ARF5/EHD4/HRAS/SPAG1/GIMAP4/TUBB3/MPPED2/RP2/RAP2B/GUF1/RHOT2/SAMHD1/TUBD1/RAP1A/RAB20/DAPK1/RRAGD/EHD1/RAB8A/RAB43/MFHAS1/RAC1/GLUD1/RAB33B/RAB29/IFI44L/LRRK2/RAB32/FPGT/GPN1/NOLC1/RAB38/RHOU/RNGTT/SAR1A/GSPT2/MTPAP/ARF1/GLUD2/ARL8A/DNM1/NMUR2/ANXA6/RIT1/GTPBP1/ATL3/IRGQ/DNM2/GNAI2/TUBA1C/TGM2/LSG1/RAB5C/RAB39B/TUBA4B/HHAT/RHOQ/NME1/MX1/NRAS/RAB5A/GFM2/TUBA4A/RHOV/RASL12/EIF5/RASL11A/ARL1/NOA1/ARFRP1/RASL11B/RHOF/ARL14/RAB7B/RRAGA/SUCLG2/DNM1L/RHOH/EEF1A2/DAP3/TUBG2/RAB8B/TUBB4A/RAB22A/RAB3A/GNA13/TUBAL3/RAB35/GUCY2D/TUBB1/TUBA1B/ARL4D/ARL15/RHOBTB3/GNL3L/GBP6/DIRAS1/EHD3/RAB3B/IFT22/HSP90AB1/AGAP3/REM2/AGAP1/ARL10/RHOA/SCG5/RAB33A/RAB3D/GFM1/RABL6/GTPBP3/GIMAP7/EIF2B2/NUDT16/RHOBTB2/EFTUD2/GNL3/LANCL2/ARF3/RASL10A/RAB27A/RAB26/RAB36/RASD2/GNA11/ARL8B/RAB28	179
MF	GO:0035586	purinergic receptor activity	17/7116	25/17697	0.004588	0.09461	0.0836	P2RY14/P2RY8/P2RX7/PTAFR/P2RY6/GPR171/P2RY12/GPR34/P2RX1/ADORA2B/P2RY13/P2RY4/P2RY10/P2RX2/ADORA3/P2RY1/P2RX5	17
MF	GO:0015923	mannosidase activity	12/7116	16/17697	0.005133	0.09799	0.08659	MANBA/MAN1C1/EDEM1/MAN2A2/MAN2B1/EDEM2/MAN1B1/MANEAL/MAN1A2/MANEA/EDEM3/MAN2B2	12
MF	GO:0032183	SUMO binding	12/7116	16/17697	0.005133	0.09799	0.08659	RNF111/HABP4/HERC2/PML/SIMC1/TDG/UBA2/TOLLIP/USPL1/CBX4/RNF4/DAXX	12
MF	GO:0070402	NADPH binding	12/7116	16/17697	0.005133	0.09799	0.08659	CBR4/SRD5A1/HMGCR/DECR1/DUS2/MTRR/QDPR/CBR3/KCNAB1/DHFR/GRHPR/CRYZ	12
MF	GO:0071617	lysophospholipid acyltransferase activity	12/7116	16/17697	0.005133	0.09799	0.08659	LPCAT2/MBOAT7/LPGAT1/PNPLA3/AGPAT3/AGPAT4/CRLS1/MBOAT2/AGPAT5/AGPAT1/TAZ/AGPAT2	12
MF	GO:0046966	thyroid hormone receptor binding	19/7116	29/17697	0.005162	0.09799	0.08659	NUP62/GAS2L1/TRIP6/OASL/ARID5A/THRAP3/NCOA3/NSD1/TAF11/MED17/MED16/MED13/NCOR1/FUS/MED4/MED30/HMGN3/MED24/TAF7	19
MF	GO:0005525	GTP binding	175/7116	374/17697	0.005309	0.09922	0.08767	RAB9A/RAC2/RAB42/GBP2/GCH1/TUBA1A/ARF6/DNM3/ARL4A/GBP1/RAP1B/RHOBTB1/GNAI3/ARL4C/RAB11A/TUBB6/RHOC/GNA15/GNL2/TRIM23/ACSM5/RRAS/GIMAP6/GBP5/NKIRAS1/RAN/KRAS/AK3/RAB31/RND3/TSR1/TUBB2A/MX2/URGCP/NKIRAS2/RAB23/GTPBP4/SAR1B/GNAQ/ARF4/PCK2/GBP4/ARL13B/ATL1/INSR/RAP2C/RAB24/MTIF2/RHOG/ARF5/EHD4/HRAS/SPAG1/GIMAP4/TUBB3/RP2/RAP2B/GUF1/RHOT2/SAMHD1/TUBD1/RAP1A/RAB20/DAPK1/RRAGD/EHD1/RAB8A/RAB43/MFHAS1/RAC1/GLUD1/RAB33B/RAB29/IFI44L/LRRK2/RAB32/FPGT/GPN1/NOLC1/RAB38/RHOU/RNGTT/SAR1A/GSPT2/ARF1/GLUD2/ARL8A/DNM1/NMUR2/ANXA6/RIT1/GTPBP1/ATL3/IRGQ/DNM2/GNAI2/TUBA1C/TGM2/LSG1/RAB5C/RAB39B/TUBA4B/HHAT/RHOQ/NME1/MX1/NRAS/RAB5A/GFM2/TUBA4A/RHOV/RASL12/EIF5/RASL11A/ARL1/NOA1/ARFRP1/RASL11B/RHOF/ARL14/RAB7B/RRAGA/SUCLG2/DNM1L/RHOH/EEF1A2/DAP3/TUBG2/RAB8B/TUBB4A/RAB22A/RAB3A/GNA13/TUBAL3/RAB35/GUCY2D/TUBB1/TUBA1B/ARL4D/ARL15/RHOBTB3/GNL3L/GBP6/DIRAS1/EHD3/RAB3B/IFT22/HSP90AB1/AGAP3/REM2/AGAP1/ARL10/RHOA/SCG5/RAB33A/RAB3D/GFM1/RABL6/GTPBP3/GIMAP7/EIF2B2/NUDT16/RHOBTB2/EFTUD2/GNL3/LANCL2/ARF3/RASL10A/RAB27A/RAB26/RAB36/RASD2/GNA11/ARL8B/RAB28	175
MF	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	22/7116	35/17697	0.005626	0.1031	0.09111	ALDH3A2/AKR1B1/ALDH9A1/FAR2/GAPDH/ALDH1A1/ALDH7A1/ADH5/ALDH6A1/AKR1C3/ALDH18A1/ALDH2/ALDH4A1/ALDH5A1/ALDH8A1/PDHB/FAR1/AKR1B10/DLAT/PDHA2/ALDH1L1/ALDH3A1	22
MF	GO:0048156	tau protein binding	27/7116	45/17697	0.00569	0.1031	0.09111	FYN/PPP2CA/SMAD2/LGMN/APOE/GSK3B/ACTB/CDK5/S100B/MARK1/CLU/TTBK1/AATF/MARK3/MARK2/STUB1/BAG2/MAP1A/PRKAA1/PIN1/HSP90AB1/BRSK1/SNCA/TTBK2/PICALM/ROCK2/BIN1	27
MF	GO:0043021	ribonucleoprotein complex binding	68/7116	133/17697	0.006799	0.1203	0.1063	EIF1/PIM1/CBX5/EZH2/EIF1B/YTHDF3/SECISBP2/EIF6/SND1/UNG/MTIF2/SECISBP2L/NAA10/HSPA5/EIF4B/NPM1/GUF1/SNRPB/DHX9/ZNF593/CSNK2B/EIF4H/EIF2S1/CD2BP2/NOLC1/DDX3X/RBM3/SNRPD1/RPN2/SNRPA/SNRPC/LETMD1/IFIH1/LETM2/SNRPB2/NME1/CPEB1/OXA1L/ETF1/PHF6/RNASEL/MTRF1L/SRP72/CPEB3/YBX3/PRMT5/PRPF31/IMPACT/UNK/SRP68/NAA16/PPP1CA/C1QBP/EIF5A/LETM1/FMR1/MDM2/MTIF3/EIF2A/MTRF1/NAA15/MTOR/TIMM50/SEC61A2/RNF135/CPEB2/NEMF/MRRF	68
MF	GO:0047485	protein N-terminus binding	57/7116	109/17697	0.006937	0.1203	0.1063	ALOX5AP/ARF6/RBPJ/TSC1/MAP2K1/BIRC2/ACTN4/NFE2/ERCC6/ERCC4/RELA/CSNK2A2/TGFB1/STXBP1/KCNIP2/NCOA3/TRAF6/ALG2/TAF11/APTX/ACOX1/SDCBP/THAP7/STX5/RPS21/ATM/BANF1/PDLIM5/SUV39H1/TARBP2/TDRD7/PEX19/YWHAQ/VWF/NPAT/PIAS3/VPS25/PPP1CC/PEX14/EIF5A/SYNGR3/MDM2/EPB41/ERCC2/EXOC4/SCFD1/LACRT/MEN1/SLA2/TERT/SNCA/PDCD10/SMARCC1/DAXX/NTSR1/EXOC2/ZMYND8	57
MF	GO:0019208	phosphatase regulator activity	51/7116	96/17697	0.006942	0.1203	0.1063	PPP1R15A/MGAT5/MTMR12/SHOC2/TESC/ZEB2/CABIN1/PPP4R2/ANP32E/PHACTR2/PPP2R3A/PHACTR1/PPP1R16A/PPP1R26/PPP1R14A/ELFN1/PPP1R37/BMP2/RCAN3/PPP1R2/PPP1R14B/PPP1R15B/PPP1R16B/PPP2R5C/ANKLE2/SBF1/PPP2R2D/BOD1L1/PPP2R2B/ELFN2/PPP1R3B/RCAN1/GTF2F1/PPP4R1/PPP1R36/PPP1R7/MYOZ1/PPP2R1B/EIF2AK2/PPP1R11/IGBP1/LMTK2/BMP2K/B3GAT3/PPP1R14D/PPP2R5B/PHACTR4/SET/SBF2/BOD1/PPP2R2C	51
MF	GO:0060090	molecular adaptor activity	114/7116	237/17697	0.007947	0.1358	0.12	SH2B2/STAM/SH3BP2/ANXA1/DOK2/SH2D3C/SH3RF1/TOB1/MLPH/DDX20/ARRDC4/GAS2L1/FBXW7/CBX5/DVL2/KHDRBS1/AKAP13/SLC9A1/GAB1/PPP4R2/ARRB1/TRIM22/COL8A2/ISCU/BAIAP2/BICD2/DDB1/CDC42SE2/ITSN1/SERINC1/NCK1/LAMTOR1/SDCBP/SHC1/HYDIN2/PDE4DIP/CRK/TRADD/SAV1/BLNK/HOMER1/DUSP19/MAVS/CNTLN/EVPL/TEX261/SUMO1/BICD1/SH3BGR/ARHGAP6/OTUD4/GRB10/SHB/AP2A2/TRAT1/LAMTOR4/DISC1/FSCN3/VPS18/AIMP2/PSMC6/CRADD/EIF3B/AP2S1/CDYL/PEX3/DET1/COX15/GRB2/SPSB1/PEF1/WWC2/STUB1/AP2A1/LAMTOR5/LASP1/SPSB2/CAV3/BIN3/MPP7/IPPK/ITSN2/FSCN1/MAP1A/BFAR/TELO2/PAG1/ERCC2/EIF4G1/ARPC4/FRMD4A/CAPN3/NUFIP1/PKP2/SKAP1/SH2D2A/MEN1/OPTN/SH2D1A/SLA2/TRIM6/CHN2/AP2M1/COL11A2/RUSC1/ST13/TIRAP/ADAP2/SOCS2/SKAP2/WWC1/LAT/SASH1/SLC9A3R2	114
MF	GO:0016423	tRNA (guanine) methyltransferase activity	10/7116	13/17697	0.00812	0.1368	0.1209	FTSJ1/TRMT5/TRMT1/TRMT1L/METTL1/WDR4/THUMPD2/TRMT11/THUMPD3/TRMT10C	10
MF	GO:0030291	protein serine/threonine kinase inhibitor activity	20/7116	32/17697	0.008942	0.1477	0.1306	PRKAR2B/CDKN2D/CDKN1A/CIB1/KAT2B/HEXIM1/HSPB1/PKIB/CDKN2B/CASP3/SFN/CDKN1C/HEXIM2/PRKAG2/CDKN1B/CDKN2C/SPRED1/SPRY2/YWHAG/PKIA	20
MF	GO:0003727	single-stranded RNA binding	50/7116	95/17697	0.009394	0.1477	0.1306	ANXA1/JMJD6/ZC3H14/AGO2/DDX60/KHDRBS1/CBX6/HNRNPH1/DAZAP1/RBM7/SRA1/ZFR/CNBP/DDX58/HNRNPA1/EIF4B/LACTB2/LARP4/DHX9/EIF4H/PUS1/IFIT5/LSM14A/MCRS1/DDX3X/ILF3/RBM3/SNRPC/IFIH1/HNRNPC/RBMS1/RBMS2/SUPT4H1/AGO1/DDX1/CBX4/POLR2D/SSB/TLR8/FMR1/DIS3L2/ATXN1/MSI2/L1TD1/PNPT1/SYNCRIP/PABPC4L/TARDBP/ENDOV/STRBP	50
MF	GO:0035091	phosphatidylinositol binding	117/7116	245/17697	0.009522	0.1477	0.1306	NRGN/MYO1G/ZFYVE26/APPL2/SNX1/BBS5/ARAP1/TPCN1/ARAP3/PLEKHA1/RPS6KC1/FCHO2/SNX10/ESYT2/PITPNA/DENND1A/SCARB1/PXDC1/SLC9A1/PIGK/SH3PXD2A/IQGAP2/PLD1/DENND1B/TWF2/TLN1/PLEK2/EXOC1/TULP3/ITPR1/PFN1/ZFYVE28/NCF4/PITPNM1/PLEKHB2/DAPP1/SNX20/NCF1/SNX18/ZCCHC2/C2CD2L/SDCBP/MARK1/KCNJ1/WIPI1/NISCH/CCDC88A/SNX33/CLVS2/GPAA1/SH3YL1/SNX27/KRIT1/HS1BP3/SNX30/KIF16B/SNX6/PLEKHA8/ZFYVE1/GOLPH3L/MPPE1/SNX13/WDR45B/KCNQ1/OSBPL2/GRB7/PLEK/WDFY1/OBSCN/SNX7/PLCD1/COMMD1/LAPTM4B/PLCB1/SCIN/ANXA2P2/PLEKHA5/PLD2/SNX5/RAB35/PLEKHA3/EPB41/SYT9/SYTL2/MYO10/ADAP1/SNX21/PXK/OGT/GSDMC/SNX19/SYT1/MAPKAP1/FZD7/SNX4/SYT5/MREG/ANXA2/SBF2/ACAP2/SNX9/TIRAP/TULP1/ADAP2/AIDA/ASAP1/AMER3/SNX16/PICALM/APPL1/LANCL2/ZFYVE19/MCF2L/FCHSD2/PLEKHN1/SNX32/SNX17	117
MF	GO:0002020	protease binding	65/7116	128/17697	0.009682	0.1477	0.1306	SERPINA1/FN1/ADAMTSL4/SELL/SERPINB9/BCL10/PINK1/TIMP2/TNFRSF10A/TNFAIP3/MBP/MIF/FLOT1/PZP/RNF139/PSAP/A2M/TNF/SH3PXD2A/GSK3B/CST3/DPP4/PANX1/CAST/RYR1/CASP3/FURIN/LDLR/ADRM1/LRP1/IL1R1/FLOT2/TIMP4/SRI/POLG/BCL2/SERPINE1/CRADD/TIMP1/DERL1/TYSND1/CSTA/UBC/RFFL/VWF/ITGA3/DERL2/FADD/ANXA2P2/INSL3/BFAR/RIOK3/SERPINB4/F3/SERPINB6/VCP/NDUFS7/ANXA2/MALT1/ACR/THAP5/ADAMTS4/SERPINF2/BIN1/OS9	65
MF	GO:0019955	cytokine binding	65/7116	128/17697	0.009682	0.1477	0.1306	IL2RG/CCR2/CX3CR1/IL27RA/IL1R2/ZFP36/GBP1/TNFRSF14/IL13RA1/ACKR3/IFNAR1/A2M/CD74/TRIM16/CSF2RA/IL18R1/CD36/IL3RA/PLP2/IL18BP/HYAL2/ITGA4/IL20RB/IL2RB/LTBP3/HMGB1/TNFRSF11A/IL1RN/IL6ST/IL1R1/CXCR1/CCR5/NRP1/NRP2/CCR6/IL12RB1/CXCR6/CCR4/EBI3/CCR3/IFNGR1/CXCR2/FZD4/WFIKKN1/IL13RA2/CNTFR/LTBP4/TGFB3/CSF3R/CD4/SPINT3/IL12B/CSF1R/ENG/CXCR3/GHR/CCR7/CER1/GREM1/ACKR2/CCRL2/TWSG1/CD109/BMPR2/GDF5	65
MF	GO:0016798	hydrolase activity, acting on glycosyl bonds	60/7116	117/17697	0.009737	0.1477	0.1306	FUCA1/HEXB/BST1/MANBA/MGAM/NAGLU/GM2A/MAN1C1/ADPRH/PSAP/HEXA/AGL/EDEM1/MAN2A2/NEIL2/UNG/GALC/MAN2B1/NAGPA/HYAL2/PARG/ADPRHL2/MACROD1/GLA/IDUA/EDEM2/TDG/CTBS/DNPH1/GUSB/HPSE/PCNA/LYZL4/NAGA/MAN1B1/GANAB/LCT/MANEAL/HYAL3/MAN1A2/MOGS/CEMIP/KLB/KL/ACER3/LYZL6/GAA/FUCA2/NEU1/ADPRHL1/SMPD1/GNE/ENGASE/MANEA/EDEM3/MAN2B2/ABHD10/TREH/MBD4/SMUG1	60
MF	GO:0004559	alpha-mannosidase activity	11/7116	15/17697	0.009759	0.1477	0.1306	MAN1C1/EDEM1/MAN2A2/MAN2B1/EDEM2/MAN1B1/MANEAL/MAN1A2/MANEA/EDEM3/MAN2B2	11
MF	GO:0044548	S100 protein binding	11/7116	15/17697	0.009759	0.1477	0.1306	EZR/S100A6/S100A11/AHNAK/S100B/AGER/FGF1/CACYBP/ATP2A2/ANXA2P2/ANXA2	11
MF	GO:0005088	Ras guanyl-nucleotide exchange factor activity	69/7116	137/17697	0.009968	0.149	0.1317	ARHGEF18/DENND5A/C9orf72/RASGEF1A/PLEKHG2/SPATA13/RASGEF1B/ARHGEF3/RASGRP3/DENND1A/ALS2/FGD6/FGD5/AKAP13/ARHGEF10L/DENND4A/ARHGEF40/DENND1B/RAPGEF2/DENND2D/DENND3/RCBTB2/ITSN1/RGL1/ADRB1/TRAPPC5/ABR/NET1/ARHGEF6/RAB3GAP1/RASGRP1/RIN2/ARHGEF2/RAP1A/SH3BP5L/DENND6B/RGL3/KALRN/RCC1/DENND4C/BCR/SBF1/RANGRF/OBSCN/RABGEF1/RASGRF1/VAV1/DOCK11/PREX1/ITSN2/RALGPS1/TRAPPC3/SMCR8/ARHGEF37/FGD3/DENND5B/ARHGEF17/KNDC1/FGD4/DENND4B/EPS8L2/DENND6A/SBF2/DENND2A/RGP1/ARHGEF4/MCF2L/ARHGEF9/RASGRP4	69
MF	GO:0033218	amide binding	165/7116	356/17697	0.0102	0.1502	0.1327	CRIP1/CRHBP/ITGAM/SLC40A1/FPR2/NOD2/RTN4R/TLR1/APBA1/TLR2/LILRB2/SRD5A1/TPP1/ECE1/MARCO/HMGCL/CD1C/TAP1/NUP214/ACOT7/FOLR2/SCARB1/GSTP1/PSAP/CD1E/SOAT1/CD74/NFKBIA/EPHB2/ALDH6A1/TNPO1/SCP2/APOE/CST3/PPIL1/PNPLA3/LDLRAD3/ITM2B/KCNIP2/CD36/PANK3/LRPAP1/INSR/HLA-F/SCTR/PANK1/TLR4/SLC7A5/HLA-DPB1/HLA-DPA1/IGF1R/HLA-E/HLA-B/CD209/TMEM158/CLTB/FURIN/AGER/ITM2A/LDLR/VIPR1/C2CD2L/CD1B/ECI2/CD300LF/PGGT1B/POM121/ACACB/LRP1/CLU/ACBD5/HLA-G/HLA-DRA/GSTM3/NOLC1/TAPBP/MCCC1/NLN/BACE2/HLA-C/IPO4/PLEKHA8/KDELR3/MGST1/NMUR2/RXRA/FTCDNL1/MMACHC/SLC7A8/TOMM40L/ACBD3/ADRB2/ITGA2/GSS/INHBA/CD1D/CD1A/PEX19/ACBD4/PCSK5/KDELR2/SLC46A1/TYMS/CTSV/SRP14/ACADVL/FZD5/GSTM4/CPTP/HADHA/TOMM20/CALR/GRPR/SRP68/LAPTM4B/CEMIP/TIMM22/DHFR/FZD4/CMA1/DBI/TM2D1/NPBWR1/GIPR/PPIC/GALR1/HCRTR1/PLEKHA3/APOA1/KPNA1/TREM2/ERAP1/HLA-A/RPS6KB2/BDKRB1/OPRD1/ERAP2/HSP90AB1/LANCL1/RXFP2/LBP/RANBP6/THOP1/NPAP1/AP2M1/OPRL1/PC/CLIP3/IAPP/GSAP/CCKBR/PPWD1/KPNB1/SEC61A2/GHR/PICALM/PPIB/ADCYAP1R1/GLTP/GRIA2/TLR6/DLGAP3/POM121C/PLEKHA8P1/CCKAR	165
MF	GO:0005096	GTPase activator activity	129/7116	273/17697	0.0103	0.1502	0.1327	HTR2B/SIPA1L1/TBC1D24/ARHGAP31/STARD8/VPS9D1/ARAP1/MYO9B/ARAP3/ALDH1A1/ADPRH/STARD13/RGS2/RASGRP3/RABGAP1L/AGFG1/RGS1/STXBP5/TBC1D15/ARHGDIA/FAM13A/ARHGEF10L/ASAP2/ARHGAP27/TBC1D5/ELMOD2/ARHGAP30/CDC42EP2/ARHGAP20/ARRB1/ARHGAP25/GNAQ/RAPGEF2/SGSM1/TBC1D1/ARHGAP19/ABR/ARHGDIB/RASA2/ARHGAP22/ARHGEF6/SRGAP3/OPHN1/RGS12/RAB3GAP1/ARFGAP3/GDI1/RP2/ARHGAP26/GDI2/RIN2/RASAL3/TBC1D2/ANKRD27/TAGAP/RABGAP1/NPRL3/TBCK/SH3BP1/AGAP4/ARHGAP24/OCRL/LRRK2/FLCN/DOCK5/TBC1D12/ARHGAP6/BCR/ARHGAP12/RALGAPB/RGS3/SRGAP2/RASA3/TBC1D17/NRP1/TBC1D9B/TBC1D20/TBC1D13/RGS14/TBC1D8/SIPA1L3/ARHGAP18/ACAP1/SYNGAP1/TBC1D8B/RGS5/TBC1D7/TBC1D22A/DNM1L/GARNL3/PLCB1/RABEP1/GMIP/PREX1/RALBP1/RUNDC1/NPRL2/RASAL1/ADAP1/TBC1D21/RGS20/NUP50/EVI5/LLGL1/TBC1D10C/RALGAPA2/RIN1/ACAP3/AGAP3/RGS6/AGAP1/ALS2CL/CHN2/SRGAP1/ACAP2/DEPDC5/CHM/GRTP1/RGS16/SIPA1L2/ADAP2/ASAP1/RGS17/SYDE1/PREB/ASAP3/SMAP2/ARFGAP1/TBC1D10B	129
MF	GO:0043024	ribosomal small subunit binding	12/7116	17/17697	0.01108	0.1597	0.1411	EIF1/PIM1/EIF1B/UNG/MTIF2/EIF4B/NPM1/EIF4H/DDX3X/NME1/MTIF3/CPEB2	12
MF	GO:0008135	translation factor activity, RNA binding	45/7116	85/17697	0.01166	0.1642	0.1451	EIF1/AGO2/C12orf65/EIF1B/EIF6/EIF4E3/MTIF2/EIF2D/EIF2B5/EIF3M/EIF4B/EIF3I/EIF2S2/EIF4E2/EIF4H/EIF2S1/EIF4G2/EIF3G/GSPT2/MCTS1/GTPBP1/EIF4G3/CPEB1/GFM2/ETF1/EIF3B/MTRF1L/EIF5/CPEB3/EEF1A2/EIF3J/EIF5A/MTIF3/EIF4G1/EIF2B1/EIF2A/EIF4E/EIF2B3/MTRF1/GFM1/EIF3L/EIF2B2/EIF1AX/CPEB2/ABTB1	45
MF	GO:0019903	protein phosphatase binding	70/7116	140/17697	0.01167	0.1642	0.1451	KCNN4/LILRB2/ATP2B4/CSK/SOD1/STAT6/STAT3/PPP1R15A/STAT1/SHOC2/AKAP11/SLC9A1/HMGCR/LILRB1/CD22/PPP3CB/KIFAP3/PHACTR1/PPP6R1/STAU1/TRAF3/CLEC12B/MVP/STRN/MFHAS1/IRS2/LCK/CDH5/ANKLE2/PTK2/ANAPC5/SPHK1/BCL2/MTMR4/BOD1L1/ANAPC7/CDKN1B/PPP1R3F/GTF2F1/KCNQ1/GRB2/FER/MAP3K5/PXN/PPP1CC/PPP1CA/EGFR/AP3B1/PPP1R11/TRAF2/HSP90B1/KAT2A/MTMR3/FBXL2/BAD/ANAPC4/IGBP1/SKAP1/CDC27/JAK1/STRN3/MTMR9/MASTL/PHACTR4/CD33/VCP/CSF1R/PDLIM4/MET/BOD1	70
MF	GO:0019902	phosphatase binding	90/7116	185/17697	0.01184	0.1647	0.1455	KCNN4/LILRB2/ATP2B4/CSK/SOD1/STAT6/STAT3/PPP1R15A/STAT1/CTSC/SMAD2/SHOC2/AKAP11/SIGLEC10/SLC9A1/HMGCR/LILRB1/CD22/PPP3CB/KIFAP3/PHACTR1/PPP6R1/STAU1/TRAF3/RCAN3/SFI1/CLEC12B/MVP/CNST/STRN/MFHAS1/IRS2/LCK/CDH5/SH3YL1/ANKLE2/PTK2/ANAPC5/SPHK1/SH3GL1/BCL2/MTMR4/PPP1R18/BOD1L1/NFATC2/ANAPC7/CDKN1B/SIGLEC11/PPP1R3F/GTF2F1/KCNQ1/GRB2/PPP1R36/FER/MAP3K5/TPRN/PXN/SPRED1/PPP1CC/PPP1CA/EGFR/PPARA/AP3B1/PPP1R11/TRAF2/HSP90B1/KAT2A/MAPK1/MTMR3/FBXL2/BAD/ANAPC4/SYTL2/IGBP1/SKAP1/CDC27/JAK1/STRN3/MTMR9/MASTL/PHACTR4/CD33/VCP/CSF1R/SBF2/PDLIM4/MET/TRPC4AP/BOD1/SLC9A3R2	90
MF	GO:0005402	carbohydrate:cation symporter activity	13/7116	19/17697	0.01212	0.1659	0.1466	SLC5A3/SLC45A4/SLC23A2/SLC45A3/SLC2A6/SLC2A9/SLC2A8/SLC5A4/SLC17A5/SLC2A10/SLC5A10/SLC5A9/SLC5A2	13
MF	GO:0042887	amide transmembrane transporter activity	27/7116	47/17697	0.0125	0.1659	0.1466	SLC19A2/AQP9/DISP1/TIMM23B/TAP2/SLC33A1/TAP1/SLC38A7/SEC61B/MCL1/TIMM17A/TAPBP/BLOC1S3/TOMM22/TOMM40L/TOMM40/SLC46A1/TOMM20/TIMM22/AQP3/CDH17/SLC15A3/SEC61G/SLC14A1/SLC25A32/ABCD1/SEC61A2	27
MF	GO:0030957	Tat protein binding	8/7116	10/17697	0.01273	0.1659	0.1466	TRIM32/DLL1/ACTB/NPM1/MDFIC/CTDP1/DNAJA1/GABARAPL1	8
MF	GO:0005540	hyaluronic acid binding	14/7116	21/17697	0.0129	0.1659	0.1466	VCAN/STAB1/CD44/TNFAIP6/HYAL2/HAPLN3/LAYN/BCAN/CEMIP/C1QBP/STAB2/LYVE1/HAPLN1/IMPG2	14
MF	GO:0010485	H4 histone acetyltransferase activity	14/7116	21/17697	0.0129	0.1659	0.1466	HAT1/KAT7/KAT8/NAA40/MCRS1/KAT5/PHF20/KANSL1L/KAT2A/OGT/USP22/KAT6B/WDR5/NAA60	14
MF	GO:0019200	carbohydrate kinase activity	14/7116	21/17697	0.0129	0.1659	0.1466	HK3/PFKFB3/PFKM/PFKP/GALK1/NAGK/FGGY/PFKFB4/KHK/PFKFB1/PFKFB2/GNE/PFKL/RBKS	14
MF	GO:0008171	O-methyltransferase activity	15/7116	23/17697	0.01348	0.1659	0.1466	MEPCE/FTSJ1/BCDIN3D/COQ3/ASMTL/LCMT1/FTSJ3/CMTR1/PCMTD2/ICMT/MRM1/PCMTD1/CMTR2/LRTOMT/COMTD1	15
MF	GO:0022884	macromolecule transmembrane transporter activity	15/7116	23/17697	0.01348	0.1659	0.1466	TIMM23B/SEC61B/SIDT1/MCL1/TIMM17A/BLOC1S3/TOMM22/TOMM40L/TOMM40/TOMM20/TIMM22/SEC61G/HNRNPA3/SIDT2/SEC61A2	15
MF	GO:0046625	sphingolipid binding	15/7116	23/17697	0.01348	0.1659	0.1466	RTN4R/SELL/LYN/S1PR1/PSAP/CD300LF/PLEKHA8/CPTP/LAPTM4B/TRAF2/PLEKHA3/CLIP3/GLTP/PLEKHA8P1/LAMA1	15
MF	GO:0030674	protein binding, bridging	83/7116	170/17697	0.01363	0.1659	0.1466	SH2B2/STAM/SH3BP2/ANXA1/DOK2/SH2D3C/TOB1/MLPH/DDX20/ARRDC4/GAS2L1/FBXW7/CBX5/DVL2/KHDRBS1/SLC9A1/GAB1/PPP4R2/ARRB1/TRIM22/COL8A2/BAIAP2/BICD2/DDB1/SERINC1/NCK1/SDCBP/SHC1/CRK/TRADD/BLNK/CNTLN/EVPL/TEX261/SUMO1/BICD1/SH3BGR/ARHGAP6/GRB10/SHB/AP2A2/TRAT1/FSCN3/VPS18/PSMC6/CRADD/AP2S1/CDYL/PEX3/DET1/GRB2/SPSB1/STUB1/AP2A1/LASP1/SPSB2/BIN3/ITSN2/FSCN1/MAP1A/BFAR/PAG1/ERCC2/ARPC4/FRMD4A/NUFIP1/SKAP1/SH2D2A/MEN1/OPTN/SH2D1A/SLA2/TRIM6/CHN2/AP2M1/COL11A2/RUSC1/ST13/TIRAP/ADAP2/SOCS2/SKAP2/LAT	83
MF	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	62/7116	123/17697	0.01373	0.1659	0.1466	ASAH1/ASRGL1/GCH1/MTHFD2/ARG2/NTAN1/SIRT4/DDAH2/SIN3A/BTD/CDADC1/ADARB1/CAT/SIRT7/HDAC11/MIER1/WDYHV1/AGA/SIRT1/APOBEC3G/SIN3B/SUDS3/APOBEC3C/BRMS1L/HDAC10/APOBEC2/VNN1/HDAC2/HDAC7/NACC2/SIRT5/ATIC/HDAC4/PADI1/ZBP1/ALLC/PGLYRP4/NGLY1/GLS/AMPD2/ADA/ACER3/APOBEC3B/PADI3/DCTD/CAD/AMDHD1/QRSL1/ADAT2/CDA/HDAC5/KLK3/AMPD3/ADAL/ADAR/ACR/AGMAT/MTA2/VNN3/ATXN3L/ADAT1/BRMS1	62
MF	GO:0003713	transcription coactivator activity	148/7116	319/17697	0.01376	0.1659	0.1466	JUNB/VDR/TRIM32/BCL10/MEF2A/JMJD6/DR1/JUND/NFYC/THRA/NCOA4/PDLIM1/PPARD/BIRC2/ACTN4/ENY2/PER2/NFE2L3/CBFB/NFE2/CTBP2/MAGED1/PCBD1/NUPR1/SUPT7L/KAT2B/THRAP3/UBE3A/UTF1/SRA1/HSF2/NCOA3/SS18L2/MTA3/NR1H2/ACTN1/RAP2C/NFKB2/MNT/ATXN7L3/HYAL2/HELZ2/RUVBL1/DYRK1B/GMEB1/CEBPA/GMEB2/DTX1/TAF5L/NPM1/ABL1/NFKBIB/TAF11/HTATIP2/NCOA7/GRIP1/NR1D2/HMGA1/CD3D/DHX9/TAF12/PML/HMGB1/SUB1/BUD31/MED17/MED27/ABT1/ARID1B/MTF1/PPARGC1A/CITED2/BCL9L/KLF7/MED16/CALCOCO1/WWOX/MED13/MAK/TRIM24/KAT5/RXRA/USP16/CCNE1/HMGB2/FUS/YY1/TSG101/NR1H3/GTF2F1/JMY/MED4/ZBTB18/MED30/NPAT/ARNT/SERTAD2/RNF20/TAF6L/ZFX/PMF1/BRCA1/PPARA/TBPL1/SS18L1/FHL2/KAT2A/GTF2A1/SS18/BRDT/WDR77/TAF4/SMARCC2/TGFB1I1/RNF4/NR2F1/RB1/ING4/CARM1/REXO4/JADE1/SOX12/EDF1/YAF2/MTDH/PSMC3IP/MED24/HINFP/USP22/MED26/CITED4/SOX4/SMARCC1/ARL2BP/NR2C2/SLC30A9/TADA3/MTA2/ACTL6A/NRIP1/DAXX/NR1H4/PSMD9/WWC1/POU3F1/TAF7/SP4/AIP	148
MF	GO:0001671	ATPase activator activity	16/7116	25/17697	0.01387	0.1659	0.1466	DNAJB1/DNAJC19/MYBPC3/ATP1B2/DNAJC1/DNAJB6/ATP1B3/GTF2H4/DNAJB4/ATP1B1/DNAJC10/DNAJC15/RAB3A/HSCB/DNAJA1/DNAJC24	16
MF	GO:0023023	MHC protein complex binding	16/7116	25/17697	0.01387	0.1659	0.1466	LILRB2/CD74/LILRB1/PKM/FAM49B/HLA-DMB/HLA-DOB/TAPBPL/HLA-DRA/HLA-DMA/ATP1B1/MS4A1/YWHAE/HSP90AB1/CD8A/HLA-DOA	16
MF	GO:0033558	protein deacetylase activity	18/7116	29/17697	0.01425	0.1671	0.1476	SIN3A/SIRT7/HDAC11/MIER1/SIRT1/SIN3B/SUDS3/BRMS1L/HDAC10/HDAC2/HDAC7/NACC2/SIRT5/HDAC4/HDAC5/MTA2/ATXN3L/BRMS1	18
MF	GO:0035035	histone acetyltransferase binding	18/7116	29/17697	0.01425	0.1671	0.1476	EPAS1/MEF2A/STAT1/CEBPB/EGR1/TRIM68/ZBTB7A/HIF1A/CREB1/MTF1/CITED2/ETS1/PCNA/BCAS3/KANSL1L/EID1/NR4A3/TAF7	18
MF	GO:1902936	phosphatidylinositol bisphosphate binding	56/7116	110/17697	0.0146	0.1687	0.1491	MYO1G/TPCN1/ARAP3/PLEKHA1/FCHO2/SLC9A1/SH3PXD2A/TWF2/PLEK2/EXOC1/TULP3/PFN1/DAPP1/SNX20/NCF1/SNX18/SDCBP/MARK1/KCNJ1/WIPI1/CLVS2/KRIT1/KIF16B/ZFYVE1/WDR45B/KCNQ1/OSBPL2/PLEK/OBSCN/PLCD1/COMMD1/LAPTM4B/PLCB1/SCIN/ANXA2P2/PLEKHA5/SNX5/RAB35/SYT9/SYTL2/ADAP1/SNX21/GSDMC/SYT1/MAPKAP1/FZD7/SYT5/ANXA2/ACAP2/TIRAP/TULP1/ADAP2/ASAP1/AMER3/PICALM/FCHSD2	56
MF	GO:0017124	SH3 domain binding	65/7116	130/17697	0.01467	0.1687	0.1491	VASP/CTTNBP2/SH3BP2/PTPN6/DPYSL3/LYN/ARHGAP31/PLSCR1/DENND1A/ADAM19/KHDRBS1/MICAL1/ARHGAP27/HCLS1/EVL/CBLB/SYNJ1/ADAM15/NCF1/PTPN22/DTX1/ABL1/TOM1L1/SYNJ2/CRK/SH3BP1/SOCS7/NOXA1/SH3BGR/ARHGAP6/DNAJC6/SH3GL1/DNM1/AFAP1L1/DNM2/ADAM12/SYNGAP1/ELMO3/GRB2/CYBA/SHANK1/CD2AP/OSTF1/ELMO1/EFS/ADAM17/ADAM9/ABI3/CCDC6/ZNF106/RAD9A/SKAP1/SH2D2A/LANCL1/ENAH/WIPF1/GPX1/PLSCR4/WAS/CD3E/GJA1/INPPL1/SHANK3/ELMO2/FMN1	65
MF	GO:0008017	microtubule binding	116/7116	246/17697	0.01543	0.1754	0.155	S100A9/S100A8/EZR/SUN2/DPYSL2/MAP1S/DNM3/GAPDH/FCHO1/RAB11A/CHP1/FCHO2/GAS2L1/EML4/VPS41/KIF9/PSRC1/MX2/KIF3B/JAKMIP2/CCDC88B/NEIL2/CETN3/MAP1LC3A/MAP4/CLIP1/CENPE/EML3/KIFC3/PAFAH1B1/CDK5RAP2/ARHGEF2/KIF4A/MAPRE1/SKA2/SPAG5/VAPB/HOOK2/NDRG1/CCDC88A/MAPRE2/KIF2A/CCSER2/LRRK2/MAP1LC3C/ZNF207/KRIT1/KIF16B/MAP7D3/GAS2L2/BCL2L11/DNM1/CCDC69/HOOK3/DNM2/RGS14/KIF24/TUBGCP3/KIF20B/MX1/CKAP5/JAKMIP1/NDEL1/GAS2L3/KIF13A/NUSAP1/DNM1L/KIF27/KATNA1/CLASP2/PEX14/TUBGCP5/FAM161A/CAPN6/CEP57/RCC2/CETN1/CETN2/MID2/CRIPT/KATNAL1/MAP1A/FMR1/KIF2C/KIF17/TPGS1/KATNB1/CLIP2/KIF1B/SKAP1/KIF5B/EML6/TRAF3IP1/POLB/MAP4K4/KIF1C/NAV3/TRPV4/SNCA/CLIP3/TTBK2/KIF12/FGF13/UXT/CCDC66/KLC3/LZTS1/TPPP/RP1/KIF14/MACF1/PRC1/GAS8/DPYSL5/STRBP/FMN1	116
MF	GO:0051015	actin filament binding	95/7116	198/17697	0.01555	0.1754	0.155	EZR/PLS1/MAP1S/FMNL1/FLNA/ACTN4/PSTPIP1/TPM3/IQGAP2/ACTR2/MICAL1/LIMA1/HCLS1/GAS7/TWF2/TLN1/CTNNA1/MARCKS/CFL2/MYO5A/CAPZA2/PANX1/ACTN1/CORO1A/CAPG/SVIL/PSTPIP2/ABL1/TAGLN/MYBPC3/CTNNAL1/AIF1/NEXN/ARPC1A/CAPZA1/BLOC1S6/ARPC1B/KPTN/CLMN/CYFIP1/MYO1C/CORO1B/MYH9/SYNE2/TPM4/MYO5C/CTNNA3/ARPC5L/LCP1/CORO2A/ABLIM3/WIPF2/FSCN3/ANXA6/COTL1/TMEM201/TPM1/AVIL/ERMN/MICALL2/PLS3/TLN2/TNNC2/CFL1/TRIOBP/ADD3/ACTR3B/DMTN/CORO1C/ACTR3/LASP1/EGFR/ABL2/SCIN/MYOM2/FSCN1/FLII/ARPC4/MYO10/SPTA1/MYH2/VPS16/WIPF1/ARPC2/MISP/TRPV4/PICK1/SHROOM1/TULP1/MYH3/ESPNL/WAS/BIN1/MACF1/ABLIM1	95
MF	GO:0017154	semaphorin receptor activity	9/7116	12/17697	0.01584	0.1754	0.155	PLXNB2/PLXNC1/PLXNA1/NRP1/PLXND1/NRP2/PLXNA3/PLXNA2/MET	9
MF	GO:0019992	diacylglycerol binding	9/7116	12/17697	0.01584	0.1754	0.155	CHPT1/RASGRP2/RASGRP3/UNC13B/DGKD/RAPGEF2/RASGRP1/CDIPT/RASGRP4	9
MF	GO:0050661	NADP binding	29/7116	52/17697	0.0166	0.1821	0.1609	POR/HIBADH/CBR4/SRD5A1/GAPDH/ME1/GSR/FMO4/HMGCR/DECR1/DUS2/CAT/MTRR/DPYD/QDPR/IDH1/G6PD/TM7SF2/SPR/CBR3/KCNAB1/DHFR/PGD/GRHPR/FMO2/CRYZ/GMDS/NNT/GLYR1	29
MF	GO:0030374	nuclear receptor transcription coactivator activity	36/7116	67/17697	0.0171	0.1859	0.1643	VDR/THRA/PPARD/ACTN4/ENY2/THRAP3/SRA1/NCOA3/NR1H2/ACTN1/ATXN7L3/HELZ2/NCOA7/NR1D2/HMGA1/BUD31/MED17/PPARGC1A/MED16/CALCOCO1/MED13/TSG101/NR1H3/MED4/MED30/PPARA/SS18/WDR77/RNF4/CARM1/PSMC3IP/MED24/USP22/SLC30A9/TADA3/NR1H4	36
MF	GO:0051213	dioxygenase activity	47/7116	91/17697	0.01757	0.1893	0.1673	ALOX5/HSPBAP1/POR/JMJD6/ASPHD2/PIR/PTGS2/ALKBH1/ADI1/PHYH/ALKBH7/TET2/KDM7A/EGLN1/ETHE1/KDM2A/IDO1/ALKBH4/HIF1AN/PLOD1/EGLN3/HAAO/KDM4B/ALOX15B/OGFOD2/FTO/KDM2B/KDM8/PLOD2/ALKBH6/KDM5B/ALKBH8/KDM6B/KDM4D/IDO2/PHYHD1/ASPHD1/KDM5C/BCO2/JMJD4/RSBN1/ALKBH2/P4HA1/TDO2/PTGS1/TET1/KDM4A	47
MF	GO:0003684	damaged DNA binding	35/7116	65/17697	0.01783	0.1904	0.1682	RAD23B/ERCC4/RAD1/NEIL2/UNG/RPA1/DDB1/APTX/XRCC5/HMGB1/POLI/TDG/POLH/PCNA/XRCC1/HMGB2/ERCC1/LOC100133315/KDM4D/SDE2/DCLRE1A/BRCA1/FANCG/DDB2/ERCC2/POLD1/XRCC6/DCLRE1C/CUL4B/POLB/POT1/AUNIP/PNKP/FEN1/RECQL4	35
MF	GO:0036041	long-chain fatty acid binding	10/7116	14/17697	0.0182	0.1909	0.1687	S100A9/S100A8/ALOX5AP/FABP4/PPARD/SCP2/FABP3/PRR7/UCP1/OXER1	10
MF	GO:0097001	ceramide binding	10/7116	14/17697	0.0182	0.1909	0.1687	RTN4R/PSAP/CD300LF/PLEKHA8/CPTP/LAPTM4B/PLEKHA3/CLIP3/GLTP/PLEKHA8P1	10
MF	GO:0004715	non-membrane spanning protein tyrosine kinase activity	26/7116	46/17697	0.01837	0.191	0.1688	FYN/LYN/CSK/HCK/JAK2/PEAK1/PTK2B/PRKCD/FGR/ABL1/PTK6/ITK/LCK/PTK2/TYK2/TEC/FER/FRK/EIF2AK2/ABL2/WEE1/MATK/JAK1/TXK/CLK1/STK16	26
MF	GO:0019001	guanyl nucleotide binding	179/7116	394/17697	0.01893	0.1922	0.1698	RAB9A/RAC2/RAB42/GBP2/GCH1/TUBA1A/ARF6/DNM3/ARL4A/GBP1/RAP1B/RHOBTB1/GNAI3/ARL4C/RAB11A/TUBB6/RHOC/GNA15/DYNC1LI1/GNL2/TRIM23/ACSM5/RRAS/GIMAP6/GBP5/NKIRAS1/RAN/KRAS/AK3/RAB31/RND3/TSR1/TUBB2A/MX2/URGCP/MIEF1/NKIRAS2/RAB23/GTPBP4/SAR1B/GNAQ/ARF4/PCK2/GBP4/ARL13B/ATL1/INSR/RAP2C/RAB24/MTIF2/RHOG/ARF5/EHD4/HRAS/SPAG1/GIMAP4/TUBB3/MPPED2/RP2/RAP2B/GUF1/RHOT2/SAMHD1/TUBD1/RAP1A/RAB20/DAPK1/RRAGD/EHD1/PDE6G/RAB8A/RAB43/MFHAS1/RAC1/GLUD1/RAB33B/RAB29/IFI44L/LRRK2/RAB32/FPGT/GPN1/NOLC1/RAB38/RHOU/RNGTT/SAR1A/GSPT2/ARF1/GLUD2/ARL8A/DNM1/NMUR2/ANXA6/RIT1/GTPBP1/ATL3/IRGQ/DNM2/GNAI2/TUBA1C/TGM2/LSG1/RAB5C/RAB39B/TUBA4B/HHAT/RHOQ/NME1/MX1/NRAS/RAB5A/GFM2/TUBA4A/RHOV/RASL12/EIF5/RASL11A/ARL1/NOA1/ARFRP1/RASL11B/RHOF/ARL14/RAB7B/RRAGA/SUCLG2/DNM1L/RHOH/EEF1A2/DAP3/TUBG2/RAB8B/TUBB4A/RAB22A/RAB3A/GNA13/TUBAL3/RAB35/GUCY2D/TUBB1/TUBA1B/ARL4D/ARL15/RHOBTB3/GNL3L/GBP6/DIRAS1/EHD3/RAB3B/IFT22/HSP90AB1/AGAP3/REM2/AGAP1/ARL10/RHOA/SCG5/RAB33A/RAB3D/GFM1/RABL6/GTPBP3/GIMAP7/EIF2B2/NUDT16/RHOBTB2/EFTUD2/GNL3/LANCL2/ARF3/RASL10A/RAB27A/RAB26/RAB36/RASD2/GNA11/ARL8B/RAB28	179
MF	GO:0032561	guanyl ribonucleotide binding	179/7116	394/17697	0.01893	0.1922	0.1698	RAB9A/RAC2/RAB42/GBP2/GCH1/TUBA1A/ARF6/DNM3/ARL4A/GBP1/RAP1B/RHOBTB1/GNAI3/ARL4C/RAB11A/TUBB6/RHOC/GNA15/DYNC1LI1/GNL2/TRIM23/ACSM5/RRAS/GIMAP6/GBP5/NKIRAS1/RAN/KRAS/AK3/RAB31/RND3/TSR1/TUBB2A/MX2/URGCP/MIEF1/NKIRAS2/RAB23/GTPBP4/SAR1B/GNAQ/ARF4/PCK2/GBP4/ARL13B/ATL1/INSR/RAP2C/RAB24/MTIF2/RHOG/ARF5/EHD4/HRAS/SPAG1/GIMAP4/TUBB3/MPPED2/RP2/RAP2B/GUF1/RHOT2/SAMHD1/TUBD1/RAP1A/RAB20/DAPK1/RRAGD/EHD1/PDE6G/RAB8A/RAB43/MFHAS1/RAC1/GLUD1/RAB33B/RAB29/IFI44L/LRRK2/RAB32/FPGT/GPN1/NOLC1/RAB38/RHOU/RNGTT/SAR1A/GSPT2/ARF1/GLUD2/ARL8A/DNM1/NMUR2/ANXA6/RIT1/GTPBP1/ATL3/IRGQ/DNM2/GNAI2/TUBA1C/TGM2/LSG1/RAB5C/RAB39B/TUBA4B/HHAT/RHOQ/NME1/MX1/NRAS/RAB5A/GFM2/TUBA4A/RHOV/RASL12/EIF5/RASL11A/ARL1/NOA1/ARFRP1/RASL11B/RHOF/ARL14/RAB7B/RRAGA/SUCLG2/DNM1L/RHOH/EEF1A2/DAP3/TUBG2/RAB8B/TUBB4A/RAB22A/RAB3A/GNA13/TUBAL3/RAB35/GUCY2D/TUBB1/TUBA1B/ARL4D/ARL15/RHOBTB3/GNL3L/GBP6/DIRAS1/EHD3/RAB3B/IFT22/HSP90AB1/AGAP3/REM2/AGAP1/ARL10/RHOA/SCG5/RAB33A/RAB3D/GFM1/RABL6/GTPBP3/GIMAP7/EIF2B2/NUDT16/RHOBTB2/EFTUD2/GNL3/LANCL2/ARF3/RASL10A/RAB27A/RAB26/RAB36/RASD2/GNA11/ARL8B/RAB28	179
MF	GO:0019213	deacetylase activity	25/7116	44/17697	0.01896	0.1922	0.1698	NDST2/SIN3A/ESD/SIRT7/HDAC11/MIER1/ADPRHL2/CES2/SIRT1/MACROD1/SIN3B/SUDS3/BRMS1L/HDAC10/HDAC2/HDAC7/NACC2/SIRT5/HDAC4/NDST1/HDAC5/MTA2/ATXN3L/OARD1/BRMS1	25
MF	GO:0015095	magnesium ion transmembrane transporter activity	11/7116	16/17697	0.01993	0.1945	0.1718	MRS2/NIPA2/CNNM2/NIPAL4/CNNM4/NIPA1/ZDHHC13/SLC41A1/TUSC3/NIPAL3/MMGT1	11
MF	GO:0016881	acid-amino acid ligase activity	11/7116	16/17697	0.01993	0.1945	0.1718	GCLM/GHDC/TTLL4/PAICS/GCLC/GSS/TTLL3/TTLL1/TPGS1/FPGS/TTLL6	11
MF	GO:0023026	MHC class II protein complex binding	11/7116	16/17697	0.01993	0.1945	0.1718	CD74/PKM/HLA-DMB/HLA-DOB/HLA-DRA/HLA-DMA/ATP1B1/MS4A1/YWHAE/HSP90AB1/HLA-DOA	11
MF	GO:0031420	alkali metal ion binding	11/7116	16/17697	0.01993	0.1945	0.1718	ATP1A1/ADPRH/PKM/TDG/HDAC4/ATP1B1/CAPN3/KCNA4/SCN9A/ATP1A2/IMPA1	11
MF	GO:0060590	ATPase regulator activity	23/7116	40/17697	0.02011	0.1945	0.1718	TSC1/PFN1/DNAJB1/DNAJC19/MYBPC3/GRPEL1/ATP1B2/DNAJC1/DNAJB6/HSPBP1/ATP1B3/GTF2H4/DNAJB4/GRPEL2/FNIP1/ATP1B1/DNAJC10/BAG2/DNAJC15/RAB3A/HSCB/DNAJA1/DNAJC24	23
MF	GO:0048487	beta-tubulin binding	22/7116	38/17697	0.02066	0.1945	0.1718	MAP1S/SYT11/RGS2/EMD/VAPB/PDCD5/BBS4/ARL8A/BCAS3/NDEL1/PEX14/TBCA/SMC3/GABARAPL1/TRPV4/SNCA/IFT74/FGF13/UXT/APPL1/GJA1/ARL8B	22
MF	GO:0030276	clathrin binding	31/7116	57/17697	0.02103	0.1945	0.1718	SYT11/AP1B1/AFTPH/ARRB1/CLTB/TOM1L1/LDLR/LRP1/TOM1L2/LRRK2/SYT6/CLTCL1/DNAJC6/AP2A2/GPR107/TOM1/AP2S1/DNM1L/AP2A1/AP4B1/CEMIP/SYT13/DNER/SYT9/SYT1/SYT2/SYT4/AP2M1/SYT5/PICALM/BIN1	31
MF	GO:0051219	phosphoprotein binding	43/7116	83/17697	0.0211	0.1945	0.1718	SH3BP2/PTPN6/SOCS3/LYN/HCK/LRP11/FBXW7/PKD2/PIK3R3/THRAP3/ARRB1/CBLB/FGR/SFN/ABL1/IGF2R/PAFAH1B1/APTX/PLCG2/SHC1/CRK/LCK/SCAF8/SHB/NEDD4/PHF6/GRB2/CBX4/RRAGA/LEO1/VAV1/ABL2/MID2/MAPK1/YWHAE/EPB41/SCAF4/TBL2/PIN1/RB1/MTOR/SNCA/SHC3	43
MF	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	48/7116	94/17697	0.02114	0.1945	0.1718	FUCA1/HEXB/MANBA/MGAM/NAGLU/GM2A/MAN1C1/PSAP/HEXA/AGL/EDEM1/MAN2A2/GALC/MAN2B1/NAGPA/HYAL2/PARG/ADPRHL2/GLA/IDUA/EDEM2/CTBS/GUSB/HPSE/LYZL4/NAGA/MAN1B1/GANAB/LCT/MANEAL/HYAL3/MAN1A2/MOGS/CEMIP/KLB/KL/ACER3/LYZL6/GAA/FUCA2/NEU1/GNE/ENGASE/MANEA/EDEM3/MAN2B2/ABHD10/TREH	48
MF	GO:0070064	proline-rich region binding	12/7116	18/17697	0.02116	0.1945	0.1718	CSK/GIGYF2/PFN1/RABAC1/BAIAP2/ITSN1/ABL1/CCND1/CYLD/PRPF40A/NEDD4/GHR	12
MF	GO:0097602	cullin family protein binding	12/7116	18/17697	0.02116	0.1945	0.1718	KCTD17/KCTD9/DCUN1D1/DDB1/RNF7/DCUN1D5/DCUN1D3/DCUN1D4/KCTD5/ANAPC11/RBX1/KCTD21	12
MF	GO:0005504	fatty acid binding	20/7116	34/17697	0.02164	0.1945	0.1718	S100A9/S100A8/ALOX5AP/FABP4/PPARD/ADH5/APOC1/SCP2/DBT/ACOX1/ACOX2/FABP3/PRR7/FFAR4/UCP1/OXER1/FABP5/PPARA/ACOX3/ALB	20
MF	GO:0008157	protein phosphatase 1 binding	13/7116	20/17697	0.02198	0.1945	0.1718	LILRB2/PPP1R15A/SHOC2/AKAP11/LILRB1/PHACTR1/STAU1/KCNQ1/FER/PPP1CC/PPP1CA/PPP1R11/PHACTR4	13
MF	GO:0019956	chemokine binding	19/7116	32/17697	0.02206	0.1945	0.1718	CCR2/CX3CR1/ZFP36/ACKR3/A2M/PLP2/ITGA4/HMGB1/CXCR1/CCR5/CCR6/CXCR6/CCR4/CCR3/CXCR2/CXCR3/CCR7/ACKR2/CCRL2	19
MF	GO:0031369	translation initiation factor binding	19/7116	32/17697	0.02206	0.1945	0.1718	TRIM32/GCH1/SYT11/ANGEL1/EIF2B5/EIF3M/NCK1/ZPR1/EIF2S2/RPS24/EIF4EBP2/DDX3X/EIF3B/EIF5/POLR2D/FMR1/EIF4G1/TBL2/EIF4E	19
MF	GO:0004721	phosphoprotein phosphatase activity	87/7116	182/17697	0.02212	0.1945	0.1718	PTPN6/DUSP1/DUSP6/PPP2CA/DUSP5/PTPN2/EYA3/DUSP10/SSH2/PPM1H/PALD1/DUSP7/PTPRC/SHOC2/PTP4A1/PTPMT1/PTPRO/PPP4C/PTPN13/DUSP3/PPP3CB/DUSP18/PPP1R3E/PTPN7/PPP1R3D/DUSP2/PTPN22/PPM1D/PPA2/PTPN4/PPM1F/DUSP19/CTDP1/PPM1M/LCK/DUSP12/RNGTT/DUSP14/DNAJC6/PPP6C/DUSP4/DUSP23/CTDSPL/PPM1N/SBF1/TAB1/PPP2R2D/MTMR4/PPP2R2B/MTMR6/CTDSP1/PPP1R3B/PPM1L/CDC25A/MTMR2/PPP4R1/PTPRN2/PPM1J/PPP1CC/PPP1CA/PPP2R1B/PDP2/CTDSP2/MTMR3/DLGAP5/PTPDC1/EYA4/MINPP1/PPEF2/RPAP2/SSH3/PDP1/PPP1CB/PHLPP2/PTPRH/DUSP13/SSH1/PTPRZ1/TIMM50/LHPP/MYH3/PPM1G/CTDSPL2/PPP2R2C/PTPRM/PTPRJ/PHPT1	87
MF	GO:0030742	GTP-dependent protein binding	14/7116	22/17697	0.02248	0.1945	0.1718	GCH1/RAPGEF6/UNC13B/RAB32/RAB38/DNM1L/AP3B1/AP1G1/RAB3A/HPS6/RAB3B/RAB3D/RASGRP4/GCHFR	14
MF	GO:0004407	histone deacetylase activity	17/7116	28/17697	0.02264	0.1945	0.1718	SIN3A/SIRT7/HDAC11/MIER1/SIRT1/SIN3B/SUDS3/BRMS1L/HDAC10/HDAC2/HDAC7/NACC2/HDAC4/HDAC5/MTA2/ATXN3L/BRMS1	17
MF	GO:1901567	fatty acid derivative binding	17/7116	28/17697	0.02264	0.1945	0.1718	S100A9/S100A8/ALOX5AP/HMGCL/ACOT7/SOAT1/ALDH6A1/SCP2/PNPLA3/ECI2/ACBD5/ACBD3/ACBD4/ACADVL/HADHA/OXER1/DBI	17
MF	GO:0019957	C-C chemokine binding	15/7116	24/17697	0.02272	0.1945	0.1718	CCR2/CX3CR1/ZFP36/ACKR3/CXCR1/CCR5/CCR6/CXCR6/CCR4/CCR3/CXCR2/CXCR3/CCR7/ACKR2/CCRL2	15
MF	GO:0001637	G protein-coupled chemoattractant receptor activity	16/7116	26/17697	0.02276	0.1945	0.1718	CCR2/CX3CR1/ACKR3/CMKLR1/CXCR1/CCR5/CCR6/CXCR6/CCR4/CCR3/CXCR2/GPR35/CXCR3/CCR7/ACKR2/CCRL2	16
MF	GO:0004950	chemokine receptor activity	16/7116	26/17697	0.02276	0.1945	0.1718	CCR2/CX3CR1/ACKR3/CMKLR1/CXCR1/CCR5/CCR6/CXCR6/CCR4/CCR3/CXCR2/GPR35/CXCR3/CCR7/ACKR2/CCRL2	16
MF	GO:0016741	transferase activity, transferring one-carbon groups	106/7116	226/17697	0.0235	0.1981	0.175	TRMT6/TPMT/MEPCE/SMYD4/FTSJ1/MTR/FAM98B/SETDB2/EZH2/HNMT/METTL14/VCPKMT/DOT1L/TRMT5/TRMT1/SUV39H2/SETD4/COQ5/PRMT9/PRDM10/METTL25/TYW3/METTL18/METTL3/NDUFAF7/NSD1/TFB1M/BCDIN3D/SETMAR/SETD5/DPH5/LCMT2/TRMT112/FAM98A/PRDM4/GATM/COQ3/TRMT61B/NSUN2/SETD9/METTL21A/SETD7/TRMT1L/SMYD3/METTL22/ASMTL/LCMT1/FBL/METTL7B/SHMT2/NTMT1/SUV39H1/ASH1L/METTL1/ATIC/SETD6/METTL8/FTSJ3/BHMT/FDXACB1/SETDB1/AS3MT/GAMT/DIMT1/TYMS/CMTR1/ZCCHC4/WDR4/ALKBH8/THUMPD2/PRMT5/TRMT11/TGS1/METTL15/SHMT1/DNMT3A/METTL23/THUMPD3/AMT/PCMTD2/ICMT/MRM1/PRDM2/CAD/PRDM6/MTFMT/FBLL1/NSUN5P1/ALDH1L1/MEN1/PCMTD1/CARM1/CMTR2/KMT2B/PRDM15/LRTOMT/TRMT10C/MGMT/EZH1/PRMT1/NSUN6/WDR82/COMTD1/WDR5/CIAPIN1/PRDM11	106
MF	GO:0008173	RNA methyltransferase activity	35/7116	66/17697	0.02352	0.1981	0.175	TRMT6/MEPCE/FTSJ1/METTL14/TRMT5/TRMT1/TYW3/METTL3/TFB1M/BCDIN3D/LCMT2/TRMT112/TRMT61B/NSUN2/TRMT1L/FBL/METTL1/METTL8/FTSJ3/FDXACB1/DIMT1/CMTR1/ZCCHC4/WDR4/ALKBH8/THUMPD2/TRMT11/TGS1/METTL15/THUMPD3/MRM1/FBLL1/CMTR2/TRMT10C/NSUN6	35
MF	GO:0016791	phosphatase activity	125/7116	270/17697	0.02369	0.1981	0.175	PTPN6/ACP5/DUSP1/NANP/DUSP6/FBP1/PPP2CA/DUSP5/ATP1A1/PTPN2/PFKFB3/NT5DC1/EYA3/DUSP10/SSH2/PPM1H/PALD1/HDHD2/PSPH/ACPP/DUSP7/PTPRC/SHOC2/PTP4A1/IMPAD1/PTPMT1/NTPCR/INPP1/PTPRO/PPP4C/PTPN13/DUSP3/SACM1L/PPP3CB/DUSP18/NT5C/PPP1R3E/SYNJ1/PTPN7/PPP1R3D/SGPP2/DUSP2/PTPN22/FIG4/PPM1D/ENOPH1/APTX/PHOSPHO2/PPA2/PTPN4/SYNJ2/PPM1F/DUSP19/CTDP1/PPM1M/OCRL/LCK/PFKFB4/DUSP12/RNGTT/DUSP14/DNAJC6/PPP6C/DUSP4/DUSP23/CTDSPL/PPM1N/SBF1/TAB1/PFKFB1/PPP2R2D/MTMR4/PPP2R2B/INPP5K/IMPA2/MTMR6/CTDSP1/ALPP/PPP1R3B/PPM1L/CDC25A/ACP6/MTMR2/PPP4R1/INPP5F/PTPRN2/PPM1J/PFKFB2/PPP1CC/PPP1CA/PPP2R1B/PDP2/CTDSP2/MTMR3/DLGAP5/PTPDC1/EYA4/MINPP1/PPEF2/RPAP2/SSH3/PDP1/PPP1CB/PHLPP2/PTPRH/NT5C3A/DUSP13/NT5M/SSH1/PTPRZ1/TIMM50/LHPP/MYH3/PPM1G/NUDT16/PNKP/UBASH3A/G6PC/CTDSPL2/PPP2R2C/INPP5A/PTPRM/PTPRJ/IMPA1/PHPT1	125
MF	GO:0016860	intramolecular oxidoreductase activity	26/7116	47/17697	0.02564	0.213	0.1882	GNPDA1/MIF/QSOX2/PIGK/PDIA3/TPI1/ECH1/RPIA/QSOX1/CYP2S1/ENOPH1/ECI2/ERP44/GSTA1/GPI/PTGES3/PDIA6/IDI1/ECI1/EBPL/EHHADH/HPGDS/HYI/DCT/TMX3/PDILT	26
MF	GO:0042578	phosphoric ester hydrolase activity	166/7116	367/17697	0.02737	0.2258	0.1995	PLD3/PTPN6/ACP5/DUSP1/PRKAR2B/NANP/DUSP6/FBP1/PPP2CA/ENPP2/DUSP5/ATP1A1/PTPN2/PFKFB3/NT5DC1/TDP2/GNB1/EYA3/DUSP10/SSH2/PPM1H/PALD1/GDE1/HDHD2/PSPH/ACPP/GPCPD1/DUSP7/PTPRC/SHOC2/PTP4A1/HMOX1/IMPAD1/PTPMT1/SMPDL3A/PDIA3/NTPCR/INPP1/PTPRO/PPP4C/PTPN13/PLD1/DUSP3/SACM1L/HDDC3/PPP3CB/DUSP18/NT5C/PPP1R3E/SYNJ1/PLCXD1/PTPN7/PPP1R3D/SGPP2/NAPEPLD/DUSP2/PTPN22/FIG4/PDE4B/PPM1D/ENOPH1/MPPED2/APTX/PHOSPHO2/PPA2/PTPN4/SAMHD1/CCL5/PLCG2/PDE6G/SYNJ2/PPM1F/DUSP19/CTDP1/PPM1M/OCRL/LCK/PFKFB4/DUSP12/PDE6D/CCR5/RNGTT/DUSP14/DNAJC6/PPP6C/ENPP7/DUSP4/DUSP23/GDPD5/CTDSPL/PPM1N/SBF1/TAB1/PFKFB1/PLCL1/PPP2R2D/MTMR4/MPPE1/PPP2R2B/INPP5K/IMPA2/MTMR6/PDE7A/CTDSP1/ALPP/PPP1R3B/PPM1L/CDC25A/ACP6/MTMR2/PPP4R1/INPP5F/PTPRN2/PPM1J/PFKFB2/PLCD1/PPP1CC/PLCB1/PPP1CA/PPP2R1B/PDP2/CTDSP2/PLD4/PLD2/PLCD4/MTMR3/DLGAP5/PTPDC1/PLCXD3/EYA4/MINPP1/PPEF2/PLCL2/RPAP2/SSH3/PDP1/PPP1CB/SMPD1/TDP1/CNP/PHLPP2/PTPRH/PDE8A/NT5C3A/DUSP13/NT5M/SSH1/PTPRZ1/SMPD2/TIMM50/LHPP/MYH3/PPM1G/NUDT16/PNKP/PGAP1/UBASH3A/G6PC/PDE8B/CTDSPL2/PPP2R2C/INPP5A/PTPRM/PTPRJ/IMPA1/PHPT1	166
MF	GO:0015932	nucleobase-containing compound transmembrane transporter activity	24/7116	43/17697	0.02764	0.2264	0.2001	SLC29A1/SLC29A3/SLC25A19/SLC25A25/SLC33A1/SIDT1/SLC35B4/SLC35D1/SLC28A3/SLC25A5/SLC29A2/SLC35B1/SLC35A3/SLC25A33/SLC35C1/SLC35A5/SLC25A24/HNRNPA3/SLC25A32/ABCD1/SIDT2/SLC35A2/SLC35D2/SLC29A4	24
MF	GO:0019888	protein phosphatase regulator activity	42/7116	82/17697	0.028	0.2269	0.2005	PPP1R15A/MGAT5/SHOC2/CABIN1/PPP4R2/PHACTR2/PPP2R3A/PHACTR1/PPP1R16A/PPP1R26/PPP1R14A/ELFN1/PPP1R37/RCAN3/PPP1R2/PPP1R14B/PPP1R15B/PPP1R16B/PPP2R5C/ANKLE2/PPP2R2D/BOD1L1/PPP2R2B/ELFN2/PPP1R3B/RCAN1/PPP4R1/PPP1R36/PPP1R7/MYOZ1/PPP2R1B/EIF2AK2/PPP1R11/IGBP1/LMTK2/B3GAT3/PPP1R14D/PPP2R5B/PHACTR4/SET/BOD1/PPP2R2C	42
MF	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	31/7116	58/17697	0.02808	0.2269	0.2005	BLVRB/SRD5A1/ACAA1/PTGR1/RETSAT/AKR1C3/ZADH2/PTGR2/DHDH/ACADM/ACADS/DECR1/DUS2/AKR1C1/DPYD/CPOX/ACOX1/TECR/ACOX2/ACADSB/BDH2/DECR2/TM7SF2/COX15/ACADVL/RSAD1/SRD5A3/ACOX3/SDHA/SDHD/DUS1L	31
MF	GO:0042826	histone deacetylase binding	55/7116	111/17697	0.02849	0.2287	0.2021	KLF4/MEF2A/DDX20/CEBPB/CBX5/GMNN/KAT2B/RELA/HIF1A/MTA3/SRF/TRAF6/TFAP4/ZBTB7B/MIER1/RBBP4/SFPQ/CCND1/RAC1/SUDS3/BCOR/TAL1/BRMS1L/HDAC10/HDAC2/AKAP8/NCOR1/MAPK8/NACC2/HDAC4/TOP2B/PHF6/HNRNPD/HES1/PKN2/HEY2/KAT2A/ZMYND15/YWHAE/RAD9A/HOXA10/CDC20/UHRF1BP1/HSP90AB1/NR2E1/HDAC5/BEX4/MTA2/NRIP1/RFXANK/KCTD21/TOP2A/HIC1/MEF2C/BRMS1	55
MF	GO:1901981	phosphatidylinositol phosphate binding	77/7116	161/17697	0.02949	0.2333	0.2062	NRGN/MYO1G/ZFYVE26/BBS5/ARAP1/TPCN1/ARAP3/PLEKHA1/FCHO2/DENND1A/SLC9A1/SH3PXD2A/IQGAP2/DENND1B/TWF2/PLEK2/EXOC1/TULP3/PFN1/ZFYVE28/NCF4/PLEKHB2/DAPP1/SNX20/NCF1/SNX18/SDCBP/MARK1/KCNJ1/WIPI1/CLVS2/SNX27/KRIT1/KIF16B/PLEKHA8/ZFYVE1/GOLPH3L/SNX13/WDR45B/KCNQ1/OSBPL2/PLEK/OBSCN/PLCD1/COMMD1/LAPTM4B/PLCB1/SCIN/ANXA2P2/PLEKHA5/SNX5/RAB35/PLEKHA3/SYT9/SYTL2/MYO10/ADAP1/SNX21/OGT/GSDMC/SNX19/SYT1/MAPKAP1/FZD7/SYT5/ANXA2/ACAP2/TIRAP/TULP1/ADAP2/ASAP1/AMER3/PICALM/LANCL2/ZFYVE19/FCHSD2/PLEKHN1	77
MF	GO:0061659	ubiquitin-like protein ligase activity	107/7116	230/17697	0.02951	0.2333	0.2062	TRIM32/HLTF/WWP1/RNF103/RNF41/SH3RF1/FBXO6/BIRC2/SIAH1/FBXO30/RNF111/RNF139/RNF149/MED10/UHRF1/RNF145/SKP2/MED11/TRIM13/RNF19B/TMEM129/UBE4B/TRIM37/UBE3A/UBE2K/ZNF451/RNF138/CBLB/RNF170/RBBP6/IRF2BP1/TRAF6/RNF217/RNF175/RNF13/ANKIB1/UBR5/RNF146/MED27/FBXL18/TRIM11/EGR2/NHLRC3/RNF115/UHRF2/MYCBP2/CBLL1/FBXL3/RNF7/ANAPC5/RNFT1/ARIH2/TRIM24/NEDD4/RNF126/KCMF1/BIRC3/UBR3/RNF24/SH3RF3/RFFL/RABGEF1/BIRC7/MED30/RING1/GID4/STUB1/HACE1/PIAS3/FANCL/FBXO4/PDZD4/WWP2/PPP1R11/BFAR/RNF43/MDM2/FBXL6/UBR1/ANAPC4/SHPRH/ZNRF1/FBXO27/ZSWIM2/FBXO44/ZNRF4/RNF185/RNF5/PRPF19/TRIM6/FBXL17/ASB1/TOPORS/ANAPC11/RNF167/RNF216/RBX1/RLIM/XIAP/PDZRN4/TRIM58/CHFR/PELI2/FBXL12/KIAA1586/SIAH2/ZNRF2	107
MF	GO:0001094	TFIID-class transcription factor complex binding	8/7116	11/17697	0.03024	0.2333	0.2062	ERCC4/RUVBL2/RUVBL1/AHR/FBL/ERCC1/EDF1/ZNHIT6	8
MF	GO:0005391	sodium:potassium-exchanging ATPase activity	8/7116	11/17697	0.03024	0.2333	0.2062	ATP1A1/ATP4A/ATP1B2/ATP1B3/ATP1B1/FXYD2/ATP1A2/ATP12A	8
MF	GO:0008556	potassium-transporting ATPase activity	8/7116	11/17697	0.03024	0.2333	0.2062	ATP1A1/ATP4A/ATP1B2/ATP1B3/ATP1B1/FXYD2/ATP1A2/ATP12A	8
MF	GO:0031996	thioesterase binding	8/7116	11/17697	0.03024	0.2333	0.2062	ARF6/TRAF6/TRAF3/RAC1/TRAF1/TRAF2/TRAF5/TRAF4	8
MF	GO:0061630	ubiquitin protein ligase activity	103/7116	221/17697	0.03052	0.234	0.2068	TRIM32/HLTF/WWP1/RNF103/RNF41/SH3RF1/FBXO6/BIRC2/SIAH1/FBXO30/RNF111/RNF139/RNF149/MED10/UHRF1/RNF145/SKP2/MED11/TRIM13/RNF19B/TMEM129/UBE4B/TRIM37/UBE3A/UBE2K/RNF138/CBLB/RNF170/RBBP6/IRF2BP1/TRAF6/RNF217/RNF175/RNF13/ANKIB1/UBR5/RNF146/MED27/FBXL18/TRIM11/NHLRC3/RNF115/UHRF2/MYCBP2/CBLL1/FBXL3/RNF7/ANAPC5/RNFT1/ARIH2/TRIM24/NEDD4/RNF126/KCMF1/BIRC3/UBR3/RNF24/SH3RF3/RFFL/RABGEF1/BIRC7/MED30/RING1/GID4/STUB1/HACE1/FANCL/FBXO4/PDZD4/WWP2/PPP1R11/BFAR/RNF43/MDM2/FBXL6/UBR1/ANAPC4/SHPRH/ZNRF1/FBXO27/ZSWIM2/FBXO44/ZNRF4/RNF185/RNF5/PRPF19/TRIM6/FBXL17/ASB1/TOPORS/ANAPC11/RNF167/RNF216/RBX1/RLIM/XIAP/PDZRN4/TRIM58/CHFR/PELI2/FBXL12/SIAH2/ZNRF2	103
MF	GO:0001103	RNA polymerase II repressing transcription factor binding	20/7116	35/17697	0.03172	0.2417	0.2135	RBPJ/BBS5/STAT3/PPARD/DDRGK1/TTC8/BBS10/SIN3A/MTA3/MIER1/BBS2/MKKS/BBS4/HDAC2/BBS7/PPARA/GTF2A1/TCF7L2/TBP/MTA2	20
MF	GO:0015662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism	19/7116	33/17697	0.03271	0.2466	0.2179	ATP6V0D2/ATP2B4/ATP1A1/ATP6V1C1/ATP4A/ATP2C1/ATP6V1G3/ATP7B/ATP1B2/ATP1B3/ATP1B1/ABCB11/ATP6V1G2/ATP2A2/ATP7A/FXYD2/ABCC4/ATP1A2/ATP12A	19
MF	GO:0016208	AMP binding	9/7116	13/17697	0.0332	0.2466	0.2179	FBP1/PFKM/PFKP/MPPED2/PRKAG2/CYB5R3/PRKAG1/PYGL/PFKL	9
MF	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	9/7116	13/17697	0.0332	0.2466	0.2179	DUSP1/DUSP6/DUSP5/DUSP10/DUSP7/DUSP18/DUSP2/DUSP14/DUSP4	9
MF	GO:0097617	annealing activity	9/7116	13/17697	0.0332	0.2466	0.2179	ANXA1/EIF4B/EIF4H/SMARCA1/DDX3X/RECQL/FMR1/RECQL4/ZRANB3	9
MF	GO:0005164	tumor necrosis factor receptor binding	18/7116	31/17697	0.03366	0.2469	0.2182	STAT1/TNF/TRIM37/TNFSF13B/TRAF6/TRAF3/TNFSF10/CASP8/TRADD/EDA/TRAF1/FADD/TRAF2/TNFSF4/SIVA1/TRAF5/TRAF4/TNFSF8	18
MF	GO:0001618	virus receptor activity	38/7116	74/17697	0.03386	0.2469	0.2182	CLEC5A/CD55/ITGA5/ITGB7/ITGB5/TNFRSF14/F11R/SCARB1/LAMP1/SLAMF1/DPP4/AXL/XPR1/NCAM1/HYAL2/CD209/LDLR/CR1/CCR5/SELPLG/PVR/ITGA2/CR2/SLC10A1/GPR15/EGFR/TFRC/SLC20A2/SIVA1/TNFRSF4/CD4/CD80/TYRO3/DAG1/CDHR3/HAVCR1/MOG/CLDN6	38
MF	GO:0104005	hijacked molecular function	38/7116	74/17697	0.03386	0.2469	0.2182	CLEC5A/CD55/ITGA5/ITGB7/ITGB5/TNFRSF14/F11R/SCARB1/LAMP1/SLAMF1/DPP4/AXL/XPR1/NCAM1/HYAL2/CD209/LDLR/CR1/CCR5/SELPLG/PVR/ITGA2/CR2/SLC10A1/GPR15/EGFR/TFRC/SLC20A2/SIVA1/TNFRSF4/CD4/CD80/TYRO3/DAG1/CDHR3/HAVCR1/MOG/CLDN6	38
MF	GO:0001846	opsonin binding	10/7116	15/17697	0.03508	0.2482	0.2193	ITGAM/CD93/PTX3/CR1/VSIG4/CALR/C1QBP/MEGF10/MASP2/APCS	10
MF	GO:0005161	platelet-derived growth factor receptor binding	10/7116	15/17697	0.03508	0.2482	0.2193	LYN/ITGA5/PDGFC/VEGFA/IL1R1/PDGFB/PDGFA/ERN1/PDGFD/PTPRJ	10
MF	GO:0030228	lipoprotein particle receptor activity	10/7116	15/17697	0.03508	0.2482	0.2193	STAB1/SCARB1/LRP8/CD36/LRP10/LDLR/LRP1/APOBR/LRP12/STAB2	10
MF	GO:0033549	MAP kinase phosphatase activity	10/7116	15/17697	0.03508	0.2482	0.2193	DUSP1/DUSP6/DUSP5/DUSP10/DUSP7/DUSP3/DUSP18/DUSP2/DUSP14/DUSP4	10
MF	GO:0042809	vitamin D receptor binding	10/7116	15/17697	0.03508	0.2482	0.2193	THRAP3/TAF11/MED17/MED16/MED13/RXRA/MED4/MED30/MED24/TAF7	10
MF	GO:0004724	magnesium-dependent protein serine/threonine phosphatase activity	11/7116	17/17697	0.03617	0.2482	0.2193	PPM1H/PPM1D/PPM1F/PPM1M/PPM1N/TAB1/PPM1L/PPM1J/PDP2/PDP1/PPM1G	11
MF	GO:0008409	5'-3' exonuclease activity	11/7116	17/17697	0.03617	0.2482	0.2193	XRN2/APTX/DCP2/CPSF3/XRN1/GEN1/DCLRE1A/EXO1/DXO/DCLRE1C/FEN1	11
MF	GO:0016493	C-C chemokine receptor activity	14/7116	23/17697	0.03648	0.2482	0.2193	CCR2/CX3CR1/ACKR3/CXCR1/CCR5/CCR6/CXCR6/CCR4/CCR3/CXCR2/CXCR3/CCR7/ACKR2/CCRL2	14
MF	GO:0001848	complement binding	13/7116	21/17697	0.03674	0.2482	0.2193	ITGAM/CD93/CD59/PTX3/CR1/VSIG4/CR2/CALR/C1QBP/CFB/MEGF10/MASP2/APCS	13
MF	GO:0016411	acylglycerol O-acyltransferase activity	13/7116	21/17697	0.03674	0.2482	0.2193	LPCAT2/MBOAT7/LPGAT1/PNPLA3/AGPAT3/DGAT2/AGPAT4/CRLS1/MBOAT2/AGPAT5/AGPAT1/TAZ/AGPAT2	13
MF	GO:0019789	SUMO transferase activity	13/7116	21/17697	0.03674	0.2482	0.2193	ZBED1/ZNF451/NSMCE2/EGR2/HDAC4/CBX4/PIAS3/MUL1/MDM2/RNF212B/UBE2I/TOPORS/KIAA1586	13
MF	GO:0038187	pattern recognition receptor activity	13/7116	21/17697	0.03674	0.2482	0.2193	TLR2/CLEC7A/FCN1/CLEC4E/MARCO/LY96/SCARB1/PTAFR/CD36/TLR4/PGLYRP4/DMBT1/TLR8	13
MF	GO:0051861	glycolipid binding	13/7116	21/17697	0.03674	0.2482	0.2193	RTN4R/SELL/LYN/CD1C/PSAP/PIGK/GPAA1/PLEKHA8/MPPE1/MANF/CLIP3/GLTP/LAMA1	13
MF	GO:0031406	carboxylic acid binding	90/7116	193/17697	0.04026	0.2705	0.2391	S100A9/S100A8/VDR/RTN4R/VCAN/ALOX5AP/FABP4/FCN1/PPARD/HMGCL/STAB1/CD44/FOLR2/ADH5/PHYH/APOC1/PSAP/SCP2/DDAH2/CD22/TNFAIP6/CEP104/DBT/NAGS/HYAL2/AKR1C1/EGLN1/IGF2R/GCLC/ACOX1/ACACB/ACOX2/GLUD1/FABP3/HIF1AN/HAPLN3/PLOD1/EGLN3/MCCC1/PRR7/SHMT2/GLUD2/PAM/OGFOD2/RXRA/FTCDNL1/LAYN/CYP26B1/SIGLEC11/PLOD2/FFAR4/GSS/GPR143/SLC46A1/TYMS/ST8SIA4/BCAN/GOT2/UCP1/OXER1/SHMT1/CEMIP/FABP5/C1QBP/DHFR/PPARA/SESN1/UBR1/ACOX3/SRR/CAD/STAB2/YARS2/DBH/CYP26A1/PYGL/CD33/PC/LYVE1/GRHPR/HAPLN1/IMPG2/CRABP2/P4HA1/TDO2/NR1H4/AARS2/SESN2/ALB/GCHFR	90
MF	GO:0017048	Rho GTPase binding	83/7116	177/17697	0.04119	0.2752	0.2432	CDC42EP4/CDC42SE1/ARHGEF18/SOD1/FMNL3/FMNL1/DIAPH1/PLEKHG2/SPATA13/MYO9B/FLNA/ARHGEF3/ALS2/FGD6/FGD5/DVL2/AKAP13/ARHGDIA/IQGAP2/ARHGEF10L/ARHGEF40/KIF3B/EXOC1/DAAM1/PFN1/CDC42EP2/PAK1/KCTD10/PPP6R1/NCF2/CDC42SE2/ITSN1/ABR/NET1/DIAPH2/ARHGDIB/ARHGEF6/SRGAP2C/SRGAP3/PAK2/ARHGEF2/SH3BP1/KALRN/OCRL/CDC42EP3/NOXA1/LRRK2/CYFIP1/BCR/SRGAP2/TRIOBP/MAP3K11/YBX3/OBSCN/PARD6B/CORO1C/RHOH/HACE1/RASGRF1/VAV1/PKN2/RCC2/DOCK11/PREX1/ITSN2/DVL1/RALBP1/INF2/ARHGEF37/FGD3/ATP7A/STRN3/ARHGEF17/FGD4/EPS8L2/SRGAP1/ARHGEF4/WAS/ROCK2/DAAM2/MCF2L/NCKAP1/ARHGEF9	83
MF	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	38/7116	75/17697	0.04257	0.2828	0.2499	MYO1G/FCHO2/SLC9A1/SH3PXD2A/TWF2/EXOC1/TULP3/PFN1/SNX20/SNX18/SDCBP/MARK1/KCNJ1/KRIT1/KCNQ1/OSBPL2/OBSCN/PLCD1/COMMD1/PLCB1/SCIN/ANXA2P2/RAB35/SYT9/SYTL2/SNX21/GSDMC/SYT1/MAPKAP1/FZD7/SYT5/ANXA2/TIRAP/TULP1/ADAP2/ASAP1/AMER3/PICALM	38
MF	GO:0004402	histone acetyltransferase activity	33/7116	64/17697	0.04306	0.283	0.25	HAT1/SUPT7L/KAT2B/NCOA3/EPC2/KAT7/TAF5L/KAT8/TAF12/NAA40/TAF5/MCRS1/KAT5/ELP3/BRPF1/DPF2/RSF1/PHF20/TAF6L/ING3/KANSL1L/CLOCK/EPC1/KAT2A/PHF10/TAF9B/OGT/MCM3AP/USP22/TADA3/KAT6B/WDR5/NAA60	33
MF	GO:0033293	monocarboxylic acid binding	33/7116	64/17697	0.04306	0.283	0.25	S100A9/S100A8/VDR/ALOX5AP/FABP4/PPARD/ADH5/APOC1/PSAP/SCP2/DBT/AKR1C1/IGF2R/ACOX1/ACACB/ACOX2/FABP3/MCCC1/PRR7/RXRA/CYP26B1/FFAR4/UCP1/OXER1/FABP5/PPARA/ACOX3/CYP26A1/PYGL/PC/CRABP2/NR1H4/ALB	33
MF	GO:0042169	SH2 domain binding	20/7116	36/17697	0.04491	0.2935	0.2594	PTPN6/NUP62/SQSTM1/JAK2/SIGLEC10/SHCBP1/LILRB1/LAT2/ABL1/NLK/CRK/LCK/PTK2/LAX1/SYNGR3/PAG1/SKAP1/TRPV4/DAG1/INPPL1	20
MF	GO:0008022	protein C-terminus binding	87/7116	187/17697	0.04572	0.2972	0.2626	FN1/EZR/BCL10/CNRIP1/PPP2CA/CSK/PFKM/PEX12/MAP2K1/CIB1/SIAH1/TNNI3K/AGO2/JAK2/ERCC6/ERCC4/PEX16/ATF4/SARNP/PTK2B/CORO1A/RABAC1/NCF2/BAIAP2/COIL/PCGF1/YEATS4/HRAS/ABL1/GRIP1/XRCC5/VTA1/MAPRE1/SIRT1/IFT46/LCK/MYO1C/IFT52/ATXN2/SUMO1/CALCOCO1/XRCC4/BANF1/SH3GL1/DNM1/ERCC1/ATP1B1/TOP2B/YWHAQ/SHANK1/SREBF2/LIG4/VPS4B/CD2AP/NPAT/AP2A1/PIAS3/PPP1CC/GPSM2/CAV3/USP7/PRKAA1/RAB3A/EPB41/ERCC2/XRCC6/MKI67/TOPBP1/ATXN1/BCAM/CDC20/SYT1/TBL1X/OPTN/TERT/OPRL1/CEP120/PICK1/HIC2/ZBTB16/EFHC1/SHANK3/TOP2A/SNX17/SASH1/LAMA1/SLC9A3R2	87
MF	GO:0008168	methyltransferase activity	99/7116	215/17697	0.04656	0.2989	0.2641	TRMT6/TPMT/MEPCE/SMYD4/FTSJ1/MTR/FAM98B/SETDB2/EZH2/HNMT/METTL14/VCPKMT/DOT1L/TRMT5/TRMT1/SUV39H2/SETD4/COQ5/PRMT9/PRDM10/METTL25/TYW3/METTL18/METTL3/NDUFAF7/NSD1/TFB1M/BCDIN3D/SETMAR/SETD5/DPH5/LCMT2/TRMT112/FAM98A/PRDM4/COQ3/TRMT61B/NSUN2/SETD9/METTL21A/SETD7/TRMT1L/SMYD3/METTL22/ASMTL/LCMT1/FBL/METTL7B/NTMT1/SUV39H1/ASH1L/METTL1/SETD6/METTL8/FTSJ3/BHMT/FDXACB1/SETDB1/AS3MT/GAMT/DIMT1/TYMS/CMTR1/ZCCHC4/WDR4/ALKBH8/THUMPD2/PRMT5/TRMT11/TGS1/METTL15/DNMT3A/METTL23/THUMPD3/AMT/PCMTD2/ICMT/MRM1/PRDM2/PRDM6/FBLL1/NSUN5P1/MEN1/PCMTD1/CARM1/CMTR2/KMT2B/PRDM15/LRTOMT/TRMT10C/MGMT/EZH1/PRMT1/NSUN6/WDR82/COMTD1/WDR5/CIAPIN1/PRDM11	99
MF	GO:0008175	tRNA methyltransferase activity	19/7116	34/17697	0.04673	0.2989	0.2641	TRMT6/FTSJ1/TRMT5/TRMT1/TYW3/BCDIN3D/LCMT2/TRMT61B/NSUN2/TRMT1L/METTL1/METTL8/WDR4/ALKBH8/THUMPD2/TRMT11/THUMPD3/TRMT10C/NSUN6	19
MF	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	19/7116	34/17697	0.04673	0.2989	0.2641	GCH1/MTHFD2/CDADC1/ADARB1/APOBEC3G/APOBEC3C/APOBEC2/ATIC/ZBP1/AMPD2/ADA/APOBEC3B/DCTD/ADAT2/CDA/AMPD3/ADAL/ADAR/ADAT1	19
MF	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	73/7116	155/17697	0.04783	0.3038	0.2685	TRMT6/TPMT/MEPCE/FTSJ1/SETDB2/EZH2/HNMT/METTL14/VCPKMT/DOT1L/TRMT5/TRMT1/SUV39H2/SETD4/COQ5/PRMT9/METTL3/NDUFAF7/NSD1/TFB1M/SETMAR/SETD5/DPH5/TRMT112/COQ3/TRMT61B/NSUN2/SETD9/METTL21A/SETD7/TRMT1L/SMYD3/METTL22/LCMT1/FBL/SUV39H1/ASH1L/METTL1/SETD6/METTL8/FTSJ3/FDXACB1/SETDB1/AS3MT/GAMT/DIMT1/CMTR1/ZCCHC4/WDR4/THUMPD2/PRMT5/TRMT11/METTL15/DNMT3A/THUMPD3/PCMTD2/ICMT/MRM1/PRDM2/PRDM6/FBLL1/MEN1/PCMTD1/CARM1/CMTR2/KMT2B/LRTOMT/TRMT10C/EZH1/PRMT1/NSUN6/WDR82/WDR5	73
MF	GO:0015298	solute:cation antiporter activity	18/7116	32/17697	0.04857	0.3038	0.2685	SLC8A1/SLC22A4/SLC11A1/SLC9A9/SLC9A1/CLCN3/SLC9A8/SLC9A7/SLC41A1/LETM1/SLC8A2/CLCN4/SLC24A4/SLC9B2/SLC24A2/CLCN5/SLC8A3/SLC9C2	18
MF	GO:0071949	FAD binding	18/7116	32/17697	0.04857	0.3038	0.2685	AIFM1/STEAP4/CYB5R1/KDM1B/SQLE/MICAL1/MICAL2/QSOX1/MTRR/AGPS/ACOX1/ACOX2/DAO/MMACHC/COQ6/CYB5R3/ACOX3/AOX1	18
MF	GO:1904680	peptide transmembrane transporter activity	18/7116	32/17697	0.04857	0.3038	0.2685	DISP1/TIMM23B/TAP2/TAP1/SEC61B/MCL1/TIMM17A/TAPBP/BLOC1S3/TOMM22/TOMM40L/TOMM40/TOMM20/TIMM22/CDH17/SLC15A3/SEC61G/SEC61A2	18
MF	GO:0008374	O-acyltransferase activity	25/7116	47/17697	0.04877	0.3038	0.2685	LPCAT2/GPAM/MBOAT7/SOAT1/LPGAT1/PNPLA3/CPT2/AGPAT3/PLA2G15/DGAT2/AGPAT4/CRLS1/MBOAT2/LCAT/HHAT/CPT1A/AGPAT5/GNPAT/CROT/AGPAT1/CHAT/TAZ/LPCAT1/AGPAT2/LPCAT3	25
MF	GO:0043548	phosphatidylinositol 3-kinase binding	17/7116	30/17697	0.05041	0.3122	0.2759	FYN/ATP1A1/JAK2/PTPN13/AXL/INSR/CORO1A/PIK3IP1/IGF1R/IRS2/LCK/DNM2/DAB1/FBXL2/TYRO3/NLRC3/RASD2	17
MF	GO:0019838	growth factor binding	65/7116	137/17697	0.05064	0.3122	0.2759	IL2RG/DUSP1/IL1R2/RHBDF2/ACVR2B/FLT1/A2M/IGFBP7/TRIM16/API5/SEC61B/CD36/IGFBP4/INSR/HYAL2/CXCL13/IL2RB/IGF1R/IGF2R/FIBP/LTBP3/FURIN/SHC1/IGFBP2/IL1RN/IL6ST/IL1R1/ACVR1B/PDGFB/S100A13/RPS19/BMPR1A/NRP1/NRP2/HTRA1/PDGFA/NKD2/FSTL4/FGFRL1/EGFR/KLB/CEP57/PCSK6/COL2A1/WFIKKN1/KL/FGFBP2/LTBP4/TGFB3/CRIM1/CSF3R/SPINT3/GLG1/ENG/HTRA4/GHR/BMPR1B/AMHR2/TWSG1/ERBB3/NTRK2/KAZALD1/CD109/BMPR2/RHBDF1	65
MF	GO:0008138	protein tyrosine/serine/threonine phosphatase activity	24/7116	45/17697	0.05111	0.3135	0.277	DUSP1/DUSP6/DUSP5/DUSP10/SSH2/DUSP7/PTP4A1/PTPMT1/DUSP3/DUSP18/DUSP2/PPM1F/DUSP19/DUSP12/RNGTT/DUSP14/DUSP4/DUSP23/SBF1/MTMR2/PTPDC1/SSH3/DUSP13/SSH1	24
MF	GO:0043130	ubiquitin binding	38/7116	76/17697	0.05285	0.3164	0.2796	TRIM32/NUP62/TNFAIP3/BIRC2/FBXW7/UCHL1/SQSTM1/UBE2N/RAD23B/PLAA/RNF19B/HSPB1/UBXN7/IKBKG/TP53INP2/UBXN2B/UBE2L6/TOM1L1/NSFL1C/ADRM1/UBR5/RBCK1/RNFT1/BUB3/NPLOC4/USP16/WDR92/NEDD4/TSG101/TOLLIP/UBAP1/MDM2/UBAP1L/UBXN1/RNF185/NBR1/UBXN11/TOP2A	38
MF	GO:0001221	transcription cofactor binding	23/7116	43/17697	0.05356	0.3164	0.2796	KLF4/FAM89B/PER2/RELA/ZBTB7A/BAIAP2/ZBTB49/AHR/CREB1/CDK9/SUMO1/VGLL4/CHD6/NFATC1/TEAD2/NFE2L2/PPARA/RORA/NR4A3/PER3/TERT/HDGF/FOXO3	23
MF	GO:0015491	cation:cation antiporter activity	15/7116	26/17697	0.05404	0.3164	0.2796	SLC8A1/SLC22A4/SLC11A1/SLC9A9/SLC9A1/SLC9A8/SLC9A7/SLC41A1/LETM1/SLC8A2/SLC24A4/SLC9B2/SLC24A2/SLC8A3/SLC9C2	15
MF	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	15/7116	26/17697	0.05404	0.3164	0.2796	BLVRB/SRD5A1/PTGR1/AKR1C3/ZADH2/PTGR2/DHDH/DECR1/AKR1C1/DPYD/TECR/BDH2/DECR2/TM7SF2/SRD5A3	15
MF	GO:0070325	lipoprotein particle receptor binding	15/7116	26/17697	0.05404	0.3164	0.2796	APOE/LRPAP1/LRP1/CLU/APOA5/AP2A1/HSP90B1/APOA1/DNAJA1/SYT1/LANCL1/AP2M1/RELN/PICALM/SNX17	15
MF	GO:0005351	carbohydrate:proton symporter activity	7/7116	10/17697	0.05629	0.3164	0.2796	SLC45A4/SLC45A3/SLC2A6/SLC2A9/SLC2A8/SLC17A5/SLC2A10	7
MF	GO:0015924	mannosyl-oligosaccharide mannosidase activity	7/7116	10/17697	0.05629	0.3164	0.2796	MAN1C1/EDEM1/MAN2A2/EDEM2/MAN1B1/MAN1A2/EDEM3	7
MF	GO:0051400	BH domain binding	7/7116	10/17697	0.05629	0.3164	0.2796	BCL2A1/MCL1/BCL2/BAX/DNM1L/BAK1/BCL2L2	7
MF	GO:0070513	death domain binding	7/7116	10/17697	0.05629	0.3164	0.2796	MCL1/TRADD/BCL2/BAX/CRADD/DAP/DAPL1	7
MF	GO:0043177	organic acid binding	94/7116	205/17697	0.05704	0.3164	0.2796	S100A9/S100A8/VDR/RTN4R/VCAN/ALOX5AP/FABP4/FCN1/PPARD/HMGCL/STAB1/CD44/FOLR2/ADH5/PHYH/APOC1/PSAP/SCP2/DDAH2/CD22/HMGCS1/TNFAIP6/CEP104/HBB/DBT/NAGS/HYAL2/AKR1C1/EGLN1/IGF2R/GCLC/ACOX1/ACACB/ACOX2/GLUD1/FABP3/HIF1AN/HAPLN3/PLOD1/EGLN3/MCCC1/PRR7/SHMT2/GLUD2/PAM/OGFOD2/RXRA/FTCDNL1/LAYN/CYP26B1/SIGLEC11/PLOD2/FFAR4/GSS/GPR143/SLC46A1/TYMS/HBQ1/ST8SIA4/BCAN/GOT2/UCP1/OXER1/SHMT1/CEMIP/FABP5/C1QBP/DHFR/PPARA/SESN1/UBR1/ACOX3/SRR/CAD/STAB2/YARS2/DBH/CYP26A1/PYGL/CD33/PC/LYVE1/GRHPR/HAPLN1/IMPG2/CRABP2/HBE1/P4HA1/TDO2/NR1H4/AARS2/SESN2/ALB/GCHFR	94
MF	GO:0000062	fatty-acyl-CoA binding	13/7116	22/17697	0.05733	0.3164	0.2796	HMGCL/ACOT7/SOAT1/ALDH6A1/SCP2/PNPLA3/ECI2/ACBD5/ACBD3/ACBD4/ACADVL/HADHA/DBI	13
MF	GO:0008565	protein transporter activity	13/7116	22/17697	0.05733	0.3164	0.2796	TIMM23B/SEC61B/MCL1/TIMM17A/BLOC1S3/TOMM22/TOMM40L/OXA1L/TOMM40/TOMM20/TIMM22/SEC61G/SEC61A2	13
MF	GO:0017025	TBP-class protein binding	13/7116	22/17697	0.05733	0.3164	0.2796	DR1/THRA/RUVBL2/RUVBL1/TAF12/AHR/TAF1B/CAND1/GTF2A1/PSMC1/PSMC5/PSMC2/CAND2	13
MF	GO:0050321	tau-protein kinase activity	13/7116	22/17697	0.05733	0.3164	0.2796	FYN/GSK3B/CSNK1D/CDK5/MARK1/TTBK1/PHKG1/MARK3/MARK2/PRKAA1/BRSK1/TTBK2/ROCK2	13
MF	GO:0005070	SH3/SH2 adaptor activity	27/7116	52/17697	0.05777	0.3164	0.2796	SH2B2/STAM/SH3BP2/SH2D3C/TOB1/KHDRBS1/GAB1/NCK1/CRK/BLNK/SH3BGR/ARHGAP6/GRB10/SHB/GRB2/LASP1/ITSN2/PAG1/SKAP1/SH2D2A/SH2D1A/SLA2/CHN2/RUSC1/SOCS2/SKAP2/LAT	27
MF	GO:0005548	phospholipid transporter activity	27/7116	52/17697	0.05777	0.3164	0.2796	PLSCR1/PITPNA/CETP/PRELID1/STARD10/PITPNM1/ABCA1/C2CD2L/ATP8B1/STARD7/MFSD2A/PLEKHA8/ABCG1/OSBPL2/ABCB4/CPTP/ABCA7/ANO4/PRELID2/PLEKHA3/APOA1/TMEM30A/PLSCR4/TRIAP1/GLTP/PLEKHA8P1/PLSCR2	27
MF	GO:0001091	RNA polymerase II basal transcription factor binding	12/7116	20/17697	0.05869	0.3164	0.2796	ERCC4/RUVBL2/RUVBL1/GTF2E1/AHR/CTDP1/FBL/ERCC1/EDF1/TBP/ZNHIT6/TAF7	12
MF	GO:0008320	protein transmembrane transporter activity	12/7116	20/17697	0.05869	0.3164	0.2796	TIMM23B/SEC61B/MCL1/TIMM17A/BLOC1S3/TOMM22/TOMM40L/TOMM40/TOMM20/TIMM22/SEC61G/SEC61A2	12
MF	GO:0008329	signaling pattern recognition receptor activity	12/7116	20/17697	0.05869	0.3164	0.2796	TLR2/CLEC7A/FCN1/MARCO/LY96/SCARB1/PTAFR/CD36/TLR4/PGLYRP4/DMBT1/TLR8	12
MF	GO:0042288	MHC class I protein binding	12/7116	20/17697	0.05869	0.3164	0.2796	LILRB2/TAP2/TAP1/BCAP31/LILRB1/HLA-E/TAPBP/DERL1/PILRA/VCP/CD244/CD8A	12
MF	GO:0004527	exonuclease activity	40/7116	81/17697	0.05871	0.3164	0.2796	ENPP2/DIS3L/RAD1/ANGEL1/ISG20/ISG20L2/XRN2/TOE1/APTX/DCP2/USB1/CPSF3/DCPS/AEN/POLG/XRN1/REXO2/EXOSC2/DDX1/GEN1/EXOSC7/DCLRE1A/CNOT7/ERI3/EXO1/POLD1/DXO/TATDN1/DCLRE1C/DIS3L2/RAD9A/EXOSC9/EXOSC3/TDP1/REXO4/APLF/PNPT1/ENDOG/FEN1/EXOSC5	40
MF	GO:0005041	low-density lipoprotein particle receptor activity	8/7116	12/17697	0.05904	0.3164	0.2796	STAB1/LRP8/CD36/LRP10/LDLR/LRP1/LRP12/STAB2	8
MF	GO:0034452	dynactin binding	8/7116	12/17697	0.05904	0.3164	0.2796	GSK3B/BICD2/PAFAH1B1/BICD1/BBS4/SNX6/HOOK3/SNX5	8
MF	GO:1990825	sequence-specific mRNA binding	8/7116	12/17697	0.05904	0.3164	0.2796	DHX9/SRSF3/ETF1/TYMS/DHFR/SSB/FMR1/SRSF4	8
MF	GO:0031435	mitogen-activated protein kinase kinase kinase binding	11/7116	18/17697	0.05974	0.3164	0.2796	ROR2/TRAF6/DUSP19/MAP4K2/DAZAP2/MAP3K11/TRAF2/MAPK1/MAP2K4/PPEF2/SASH1	11
MF	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	9/7116	14/17697	0.0602	0.3164	0.2796	MIF/ECH1/ECI2/GSTA1/IDI1/ECI1/EBPL/EHHADH/DCT	9
MF	GO:0045125	bioactive lipid receptor activity	9/7116	14/17697	0.0602	0.3164	0.2796	S1PR4/S1PR3/S1PR1/LPAR2/SPHK1/LPAR3/LPAR1/GPR6/S1PR5	9
MF	GO:0050998	nitric-oxide synthase binding	9/7116	14/17697	0.0602	0.3164	0.2796	ATP2B4/DNM3/CD74/ACTB/DMD/DNM1/DNM2/CAV3/SNTA1	9
MF	GO:0052745	inositol phosphate phosphatase activity	9/7116	14/17697	0.0602	0.3164	0.2796	IMPAD1/INPP1/OCRL/INPP5K/IMPA2/INPP5F/MINPP1/INPP5A/IMPA1	9
MF	GO:0035257	nuclear hormone receptor binding	71/7116	152/17697	0.06031	0.3164	0.2796	VDR/NR4A2/STAT3/NUP62/JUND/NCOA4/GAS2L1/ACTN4/STAT1/YWHAH/TRIP6/CEBPB/OASL/CTBP2/RAN/ARID5A/THRAP3/TRIM68/ZBTB7A/ARRB1/HIF1A/NCOA3/LATS1/NSD1/FLT3/ETS2/TAF11/NCOA7/GRIP1/HMGA1/STRN/WIPI1/BUD31/MED17/SIRT1/PPARGC1A/MED16/SUMO1/MED13/NCOR1/TRIM24/KAT5/RXRA/CCNE1/PCNA/BCAS3/FUS/MED4/MED30/CALR/HMGN3/MED25/DCAF13/BRCA1/FHL2/TCF7L2/NR4A3/TGFB1I1/RNF4/RB1/MED24/DDX54/FOXP1/SLC30A9/TADA3/NRIP1/C1D/DAXX/NR1H4/TAF7/FOXH1	71
MF	GO:0005149	interleukin-1 receptor binding	10/7116	16/17697	0.06032	0.3164	0.2796	TRIP6/IL1RAP/IRAK4/TLR5/IL1B/IL1RN/TOLLIP/IL1A/ERAP1/IL37	10
MF	GO:0005159	insulin-like growth factor receptor binding	10/7116	16/17697	0.06032	0.3164	0.2796	IGF1/YWHAH/ARRB1/INSR/SHC1/CRK/SOCS1/REN/YWHAG/SOCS2	10
MF	GO:0035259	glucocorticoid receptor binding	10/7116	16/17697	0.06032	0.3164	0.2796	NR4A2/STAT3/YWHAH/CEBPB/FLT3/ETS2/GRIP1/SUMO1/NR4A3/NRIP1	10
MF	GO:0017147	Wnt-protein binding	20/7116	37/17697	0.06162	0.3208	0.2835	WLS/PTPRO/LRP5/AXL/ROR2/FZD9/SFRP4/ROR1/FZD5/FZD1/FZD4/MERTK/CTHRC1/FZD7/TYRO3/FZD2/MET/SFRP5/APCDD1/FZD10	20
MF	GO:0050660	flavin adenine dinucleotide binding	39/7116	79/17697	0.06169	0.3208	0.2835	POR/AIFM1/STEAP4/CYB5R1/KDM1B/SQLE/AIFM2/GSR/FMO4/TXNRD1/MICAL1/ETFA/ACADM/ACADS/MICAL2/QSOX1/DUS2/MTRR/DPYD/AGPS/FOXRED2/ACOX1/ETFDH/ACOX2/ACADSB/DAO/MMACHC/COQ6/CYBB/ACADVL/CYB5R3/MAOB/ACOX3/SDHA/MTO1/FMO2/DUS1L/CHDH/AOX1	39
MF	GO:0051427	hormone receptor binding	85/7116	185/17697	0.06441	0.3325	0.2938	VDR/FYN/NR4A2/FABP4/STAT3/NUP62/JUND/NCOA4/GAS2L1/ACTN4/STAT1/YWHAH/TRIP6/CEBPB/JAK2/OASL/CTBP2/RAN/ARID5A/THRAP3/TRIM68/ZBTB7A/ARRB1/HIF1A/NCOA3/LEP/LATS1/NSD1/FLT3/ETS2/TAF11/NCOA7/GRIP1/HMGA1/STRN/WIPI1/BUD31/MED17/SIRT1/PPARGC1A/MED16/SUMO1/MED13/NCOR1/TRIM24/KAT5/RXRA/CCNE1/PCNA/BCAS3/FUS/TYK2/MED4/MED30/CALR/HMGN3/MED25/DCAF13/BRCA1/FHL2/GPHB5/TCF7L2/GPHA2/JAK1/VIP/NR4A3/TGFB1I1/PTHLH/RNF4/RB1/PSMC5/MED24/DDX54/FOXP1/GHRH/SLC30A9/TADA3/SOCS2/NRIP1/C1D/DAXX/NR1H4/UCN3/TAF7/FOXH1	85
MF	GO:0004713	protein tyrosine kinase activity	63/7116	134/17697	0.0645	0.3325	0.2938	FYN/LYN/CSK/FLT1/HCK/MAP2K1/JAK2/DYRK4/ALK/EPHB2/DYRK2/PEAK1/AXL/PTK2B/PRKCD/ROR2/INSR/DYRK1B/FLT3/FGR/IGF1R/ABL1/IGF2R/PTK6/TESK2/ITK/LCK/EPHA8/EPHA10/PTK2/NRP1/NRP2/TYK2/TEC/MAP2K2/FER/FRK/HIPK1/FGFRL1/DYRK3/EIF2AK2/EGFR/ABL2/MERTK/MAP2K4/WEE1/MATK/EPHB1/LMTK2/JAK1/HIPK3/CRIM1/RET/TXK/MAP2K5/CSF1R/CLK1/TYRO3/MET/STK16/ERBB3/NTRK2/EFNA3	63
MF	GO:0001085	RNA polymerase II transcription factor binding	72/7116	155/17697	0.0663	0.3389	0.2995	KLF4/FOS/SPI1/MEF2A/MAD2L2/FBP1/RBPJ/BBS5/STAT3/BHLHE40/PPARD/DDRGK1/TTC8/LDB1/ERCC4/GSK3B/BBS10/ATF4/HCLS1/SIN3A/LMO2/MTA3/SRF/RUVBL2/RUVBL1/GTF2E1/IFI27/DHX9/MIER1/MGA/AHR/CREB1/BBS2/MKKS/EGR2/CTDP1/TAL1/BBS4/FBL/HDAC2/NCOR1/NFATC1/ERCC1/HDAC4/ID2/BEX1/BBS7/PITX3/TEAD2/MAMSTR/PIAS3/NFE2L2/WWP2/PPARA/HEY2/GTF2A1/TCF7L2/RBL2/EXOSC9/TBX4/RB1/EDF1/MTDH/PITX1/TBP/TBX21/HDAC5/ZNHIT6/MTA2/TBX15/TBX22/TAF7	72
MF	GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	29/7116	57/17697	0.06659	0.3389	0.2995	DIS3L/RAD1/ANGEL1/ISG20/ISG20L2/XRN2/TOE1/APTX/DCP2/USB1/XRN1/REXO2/EXOSC2/GEN1/EXOSC7/DCLRE1A/CNOT7/ERI3/EXO1/POLD1/TATDN1/DCLRE1C/DIS3L2/RAD9A/EXOSC9/EXOSC3/PNPT1/FEN1/EXOSC5	29
MF	GO:0043022	ribosome binding	29/7116	57/17697	0.06659	0.3389	0.2995	YTHDF3/EIF6/NAA10/HSPA5/GUF1/EIF2S1/RPN2/LETMD1/LETM2/CPEB1/OXA1L/ETF1/MTRF1L/SRP72/CPEB3/IMPACT/SRP68/NAA16/C1QBP/EIF5A/LETM1/FMR1/MTIF3/EIF2A/MTRF1/NAA15/MTOR/SEC61A2/CPEB2	29
MF	GO:0061733	peptide-lysine-N-acetyltransferase activity	33/7116	66/17697	0.06788	0.3425	0.3027	HAT1/SUPT7L/KAT2B/NCOA3/EPC2/KAT7/TAF5L/KAT8/TAF12/NAA40/TAF5/MCRS1/KAT5/ELP3/BRPF1/DPF2/RSF1/PHF20/TAF6L/ING3/KANSL1L/CLOCK/EPC1/KAT2A/PHF10/TAF9B/OGT/MCM3AP/USP22/TADA3/KAT6B/WDR5/NAA60	33
MF	GO:0034212	peptide N-acetyltransferase activity	37/7116	75/17697	0.06817	0.3425	0.3027	HAT1/SUPT7L/KAT2B/NAA20/NCOA3/EPC2/NAA10/KAT7/TAF5L/KAT8/TAF12/NAA40/TAF5/MCRS1/KAT5/ELP3/BRPF1/DPF2/RSF1/PHF20/TAF6L/NAA16/ING3/KANSL1L/CLOCK/EPC1/KAT2A/PHF10/TAF9B/OGT/MCM3AP/NAA15/USP22/TADA3/KAT6B/WDR5/NAA60	37
MF	GO:0048029	monosaccharide binding	37/7116	75/17697	0.06817	0.3425	0.3027	TALDO1/HK3/FBP1/MANBA/PFKM/PFKP/LMAN2L/PHYH/SLC2A3/M6PR/GALK1/SLC2A8/GYS1/RPIA/CD209/EGLN1/IGF2R/ALDOA/GPI/G6PD/PLOD1/EGLN3/GNPNAT1/PAM/OGFOD2/PLOD2/ALPK1/LMAN1/LGALS9/CLN5/COL20A1/DBH/PYGL/ENG/ACR/PFKL/P4HA1	37
MF	GO:0008375	acetylglucosaminyltransferase activity	28/7116	55/17697	0.07007	0.3506	0.3098	HEXB/EXTL2/NDST2/MGAT2/B3GNT8/MGAT5/POMGNT2/LFNG/PIGP/EXT2/EXT1/HEXA/MGAT4B/B3GNT2/B3GNT5/XYLT1/GCNT1/XYLT2/MGAT3/PIGQ/NDST1/MGAT5B/ALG13/PIGH/B3GNT4/OGT/GCNT2/ALG14	28
MF	GO:1901505	carbohydrate derivative transmembrane transporter activity	23/7116	44/17697	0.07055	0.3516	0.3107	SLC29A1/SLC29A3/SLC37A2/SLC25A25/SLC33A1/SLC37A4/SLC35B4/SLC35D1/SLC28A3/SLC25A5/SLC50A1/SLC29A2/SLC17A5/SLC35B1/SLC35A3/SLC35C1/SLC35A5/SLC17A4/SLC25A24/ABCD1/SLC35A2/SLC35D2/SLC29A4	23
MF	GO:0000030	mannosyltransferase activity	16/7116	29/17697	0.07404	0.3674	0.3247	TMTC3/PIGV/ALG2/SDF2L1/DPY19L4/PIGB/DPM1/TMTC2/ALG12/POMT1/POMT2/DPM3/DPY19L2/DPY19L2P2/ALG8/ALG3	16
MF	GO:0030246	carbohydrate binding	121/7116	271/17697	0.07552	0.3719	0.3286	CD69/CLEC5A/TALDO1/HK3/SELL/CLEC7A/VCAN/FBP1/ENPP2/OLR1/LY75/CLEC4D/MANBA/MGAM/MGAT2/CD72/FCN1/PFKM/MRC2/PFKP/LMAN2L/CLEC4E/GALM/FBXO6/GALNT14/CD93/GPCPD1/PHYH/SLC2A3/SIGLEC10/CLEC12A/AGL/M6PR/CD22/GALK1/SLC2A8/CHID1/MAN2A2/UAP1/MAN2B1/GYS1/PTX3/CLC/LOXL2/RPIA/CD209/EGLN1/CRYBG3/IGF2R/ALDOA/CLEC12B/ATRN/GALNT7/PRG2/CHI3L2/GPI/CDIPT/CHI3L1/EVA1C/DGCR2/SIGLEC16/HLA-DRA/G6PD/PLOD1/EGLN3/CLEC2B/ITLN1/GNPNAT1/SIGLEC7/GALNT6/KLRB1/GUSB/GALNT12/GALNT10/PAM/OGFOD2/CLEC1A/FCER2/LAYN/SIGLEC11/CLEC11A/PLOD2/LGALS1/GANAB/PPP1R3F/ASGR2/MLEC/ALPK1/LMAN1/LGALS9/CLN5/SORD/BCAN/CANX/CALR/COL20A1/GALNT9/REG3G/GAA/CLEC3A/PKD1L2/CD34/DBH/LGALS2/PYGL/CD33/ASGR1/SIGLEC1/CHODL/ENG/GALNT1/ACR/MAN2B2/PFKL/P4HA1/SIGLEC9/CNTN1/SUSD2/OS9/APCS/GALNT15	121
MF	GO:0003714	transcription corepressor activity	107/7116	238/17697	0.07586	0.3719	0.3286	JUNB/CBFA2T3/JAZF1/NFIL3/SKI/PARP9/DR1/BHLHE40/CREG1/BATF3/TDP2/DRAP1/TOB1/ATF5/LDB1/CTBP2/EZH2/UBP1/RYBP/ARID5A/GMNN/ZHX3/ZBTB7A/SIN3A/ZNF451/DNAJB1/TRIM22/TLE1/MTA3/ZNF281/E2F6/IRF2BP1/MNT/KCTD1/RUVBL2/NSD1/HSF4/GON4L/TLE4/RELB/MIER1/ERF/SIRT1/BASP1/CCND1/SIN3B/CITED2/BCOR/SCAI/NCOR1/HDAC7/MYBBP1A/N4BP2L2/NACC2/LMCD1/HSBP1/ZNF136/NOC2L/HDAC4/YY1/DPF2/TSG101/CTCF/TLE6/ZMYND11/CDYL/CBX4/KDM5B/TGIF1/YBX3/PRMT5/NPAT/COPS2/PEX14/C1QBP/CNOT7/DNMT3A/TAF9B/AEBP2/EID1/TFCP2L1/ZNF653/MXI1/JDP2/PFDN5/TBL1X/YAF2/ZNF85/DDX54/SAP18/RLIM/HSBP1L1/EZH1/MTA2/UXT/NRIP1/C1D/DAXX/TONSL/RCOR3/NR1H4/AEBP1/HDGF/E2F8/SIAH2/ZMYND8/LHX9	107
MF	GO:0008234	cysteine-type peptidase activity	84/7116	184/17697	0.07586	0.3719	0.3286	ATG4C/USP51/USP3/CTSF/CAPN2/JOSD1/TNFAIP3/OTUD6B/CTSS/USP45/CASP6/CTSC/UCHL1/LGMN/CAPN15/PGPEP1/USP54/CTSK/SENP6/PIGK/PDIA3/USP28/CLC/ZRANB1/USP46/USP9X/CASP3/CTSZ/CASP8/CTSB/CAPNS2/CASP5/CASP7/OTUD1/UCHL5/RCE1/CYLD/ESPL1/OTUD4/USP4/USP16/USP31/CAPN9/ATG4B/USP26/CASP2/OTUD5/DESI2/SENP8/USP1/CASP1/USPL1/STAMBPL1/CAPN5/CTSV/USP30/ALG13/USP27X/USP11/ATXN3/CAPN6/USP10/YOD1/USP7/USP35/CASP4/STAMBP/USP49/CAPN3/CTSW/OTUD3/BAP1/ATG4D/ATG4A/USP22/CTSO/BRCC3/MALT1/USP19/USP37/ATXN3L/JOSD2/USP32/CAPNS1	84
MF	GO:0045309	protein phosphorylated amino acid binding	26/7116	51/17697	0.07766	0.378	0.3341	SH3BP2/PTPN6/SOCS3/HCK/FBXW7/PIK3R3/ARRB1/CBLB/FGR/ABL1/PLCG2/SHC1/CRK/LCK/SCAF8/SHB/NEDD4/GRB2/LEO1/VAV1/ABL2/MAPK1/YWHAE/SCAF4/PIN1/SHC3	26
MF	GO:0042277	peptide binding	131/7116	295/17697	0.07793	0.378	0.3341	CRIP1/CRHBP/ITGAM/SLC40A1/FPR2/NOD2/TLR1/APBA1/TLR2/LILRB2/TPP1/ECE1/MARCO/CD1C/TAP1/NUP214/SCARB1/GSTP1/CD1E/CD74/NFKBIA/EPHB2/TNPO1/APOE/CST3/PPIL1/LDLRAD3/ITM2B/KCNIP2/CD36/LRPAP1/INSR/HLA-F/SCTR/TLR4/SLC7A5/HLA-DPB1/HLA-DPA1/IGF1R/HLA-E/HLA-B/CD209/TMEM158/CLTB/FURIN/AGER/ITM2A/LDLR/VIPR1/C2CD2L/CD1B/PGGT1B/POM121/LRP1/CLU/HLA-G/HLA-DRA/GSTM3/NOLC1/TAPBP/NLN/BACE2/HLA-C/IPO4/KDELR3/MGST1/NMUR2/RXRA/MMACHC/SLC7A8/TOMM40L/ADRB2/ITGA2/GSS/INHBA/CD1D/CD1A/PEX19/PCSK5/KDELR2/CTSV/SRP14/FZD5/GSTM4/TOMM20/CALR/GRPR/SRP68/CEMIP/TIMM22/FZD4/CMA1/TM2D1/NPBWR1/GIPR/PPIC/GALR1/HCRTR1/APOA1/KPNA1/TREM2/ERAP1/HLA-A/RPS6KB2/BDKRB1/OPRD1/ERAP2/HSP90AB1/LANCL1/RXFP2/LBP/RANBP6/THOP1/NPAP1/AP2M1/OPRL1/IAPP/GSAP/CCKBR/PPWD1/KPNB1/SEC61A2/GHR/PICALM/PPIB/ADCYAP1R1/GRIA2/TLR6/DLGAP3/POM121C/CCKAR	131
MF	GO:0061650	ubiquitin-like protein conjugating enzyme activity	21/7116	40/17697	0.07808	0.378	0.3341	UBE2Z/UBE2N/UBE2Q2/UBE2K/UBE2S/UBE2D3/UBE2D2/UBE2L6/UBE2J1/UBE2W/UBE2E1/UBE2A/UBE2F/UBE2G2/UBE2E2/UBE2D4/UBE2C/UBE2I/UBE2G1/UBE2B/UBE3B	21
MF	GO:0016407	acetyltransferase activity	52/7116	110/17697	0.07886	0.3795	0.3353	LPCAT2/HAT1/SAT1/SUPT7L/KAT2B/NAA20/NCOA3/DBT/NAGS/EPC2/NAA10/KAT7/TAF5L/KAT8/TAF12/NAA40/TAF5/GNPNAT1/NAT10/MCRS1/SPHK1/KAT5/ELP3/BRPF1/DPF2/RSF1/PHF20/HADHA/DLAT/TAF6L/NAA16/ING3/KANSL1L/CLOCK/ACAA2/EPC1/KAT2A/PHF10/TAF9B/GNPAT/OGT/MCM3AP/NAT2/NAA15/CHAT/USP22/NAT1/LPCAT1/TADA3/KAT6B/WDR5/NAA60	52
MF	GO:0000049	tRNA binding	30/7116	60/17697	0.07914	0.3795	0.3353	ALKBH1/SEPSECS/SLFN11/TRMT1/AIMP1/XPOT/NSUN2/SLFN13/TRMT1L/DTD1/PUS1/IFIT5/PSTK/IARS2/METTL1/HSD17B10/ALKBH8/TRMT11/YRDC/SSB/EIF2A/YARS2/DARS2/DTD2/TERT/EIF2AK4/TRMT10C/NSUN6/AARS2/NEMF	30
MF	GO:0048365	Rac GTPase binding	34/7116	69/17697	0.07932	0.3795	0.3353	SOD1/FMNL1/SPATA13/FLNA/ALS2/DVL2/ARHGDIA/IQGAP2/PAK1/NCF2/ARHGDIB/SRGAP2C/SRGAP3/PAK2/ARHGEF2/SH3BP1/OCRL/NOXA1/CYFIP1/SRGAP2/MAP3K11/CORO1C/HACE1/VAV1/RCC2/PREX1/DVL1/RALBP1/ATP7A/EPS8L2/SRGAP1/ARHGEF4/WAS/NCKAP1	34
MF	GO:0022804	active transmembrane transporter activity	159/7116	362/17697	0.08099	0.3859	0.341	SLC8A1/ATP6V0D2/SLCO4A1/SLC47A1/SLC22A4/ATP2B4/ABCC5/SLC5A3/SLC11A1/SLC45A4/SLC9A9/SLC36A1/ATP1A1/ATP6AP1/SLC23A2/SLCO3A1/ATP8A1/TIMM23B/SLC37A2/SLC22A18/PCYOX1/ATP6V1C1/SLC46A2/TAP2/SLC33A1/TAP1/ABCD4/CLCN7/SLC22A5/SLC45A3/SLC37A4/SLC2A6/SLC6A16/SLC7A11/ATP6V0C/SLC9A1/SLC2A9/CD320/SLC26A11/SLCO2B1/SLC2A8/ABCD3/SEC61B/SLCO4C1/SLC7A6/MCU/TCIRG1/ABCB6/SLC16A10/SLC1A4/CLCN3/ATP6V1A/ATP4A/ABCA1/TIMM17A/SLC12A9/SLC25A10/ATP2C1/SLC35D1/ABCB10/ATP6V1G3/ATP7B/ATP1B2/ATP6V1B2/ABCA5/SLC28A3/SLC9A8/SLC25A5/SLC10A3/TAPBP/SLC38A1/SLC9A7/ATP6V1D/ATP1B3/SLC12A2/ABCB5/SLC16A6/ATP6AP1L/MFSD2A/SLC26A8/SLC12A8/SLC35E1/SLC6A5/ATP6V0E2/ATP1B1/ABCG1/SLC16A2/SLC16A1/ABCB4/SLC10A1/SLC5A6/ABCB11/SLC4A5/SLC5A4/SLC13A2/ATP6V1G2/SLC17A5/SLC20A1/LMBRD1/TOMM20/SLC26A4/SLC16A7/SLC41A1/ABCA7/SLC36A4/SLC35C1/ABCA11P/ABCC10/ATP2A2/CDH17/LETM1/SLC15A3/SLC5A8/SLC20A2/SLC8A2/SLC17A4/RALBP1/SEC61G/CLCN4/SLC25A16/SLC4A7/SLC4A1/SLC2A10/SLC24A4/ATP7A/ABCA6/FXYD2/SLC22A8/SLC12A1/SLC12A7/ABCC3/ABCC4/SLC5A10/SLC6A13/SLCO1C1/SLC25A22/SLC9B2/SLC24A2/ABCD1/SLC12A4/SLC26A10/SLC5A9/SLC6A12/CLCN5/ATP1A2/SLC8A3/SLC4A11/MFSD3/SLC9C2/ATP12A/SLC35D2/SLC5A2/ABCB7/SLC4A3/SLC29A4/SLC2A13/SLC12A6/SLCO1B1/SLC16A5	159
MF	GO:0004532	exoribonuclease activity	20/7116	38/17697	0.08216	0.39	0.3446	DIS3L/ANGEL1/ISG20/ISG20L2/XRN2/TOE1/DCP2/USB1/DCPS/XRN1/REXO2/EXOSC2/EXOSC7/CNOT7/ERI3/DIS3L2/EXOSC9/EXOSC3/PNPT1/EXOSC5	20
MF	GO:0001786	phosphatidylserine binding	29/7116	58/17697	0.08334	0.394	0.3481	APPL2/SYT11/FCHO2/SCARB1/AXL/TLN1/ANXA9/RASGRP1/CD300LF/MARK1/HMGB1/SYT6/ANXA6/CD300A/SYT13/SCIN/ANXA2P2/CPNE1/SYT9/SYTL2/GSDMC/SYT1/SYT2/SYT4/SYT5/ANXA2/ASAP1/APPL1/PLEKHN1	29
MF	GO:0016896	exoribonuclease activity, producing 5'-phosphomonoesters	19/7116	36/17697	0.08649	0.4031	0.3562	DIS3L/ANGEL1/ISG20/ISG20L2/XRN2/TOE1/DCP2/USB1/XRN1/REXO2/EXOSC2/EXOSC7/CNOT7/ERI3/DIS3L2/EXOSC9/EXOSC3/PNPT1/EXOSC5	19
MF	GO:0008080	N-acetyltransferase activity	43/7116	90/17697	0.08763	0.4031	0.3562	HAT1/SAT1/SUPT7L/KAT2B/NAA20/NCOA3/NAGS/EPC2/NAA10/KAT7/TAF5L/KAT8/TAF12/NAA40/TAF5/GNPNAT1/NAT10/MCRS1/KAT5/ELP3/BRPF1/DPF2/RSF1/PHF20/TAF6L/NAA16/ING3/KANSL1L/CLOCK/EPC1/KAT2A/PHF10/TAF9B/OGT/MCM3AP/NAT2/NAA15/USP22/NAT1/TADA3/KAT6B/WDR5/NAA60	43
MF	GO:0043621	protein self-association	28/7116	56/17697	0.0878	0.4031	0.3562	MYD88/TRIM32/BCL10/FHOD1/TNFAIP3/CD2/CTSC/LDB1/ADAM8/DVL2/KCTD9/TMEM43/VPS41/SGTA/ABCD3/FLT3/RSAD2/CCL5/AGA/CRK/TDG/DMTN/GPSM2/ATXN1/ZSWIM2/FOXP1/MALT1/SHANK3	28
MF	GO:0042393	histone binding	89/7116	197/17697	0.08795	0.4031	0.3562	USP51/USP3/PARP9/PHF19/STAT1/MCM2/KDM1B/JAK2/CBX5/HAT1/WDR5B/UHRF1/CHD1/ANP32E/KDM7A/CHD2/UIMC1/DEK/MSL3/KAT7/PWWP2A/NPM1/DNAJC2/KAT8/PHIP/RBBP4/SIRT1/RCC1/UHRF2/NCAPD3/DTX3L/ING1/KMT2E/TRIM24/KAT5/PTMA/USP16/KDM8/NOC2L/BCAS3/ANP32C/DPF2/ATAD2B/SSRP1/ZMYND11/PHF6/RSF1/CDYL/CD1D/CBX4/KDM5B/BRD9/BRD2/COPRS/RNF20/PWP1/ING3/VPS72/IPO9/FMR1/PHF10/IPO7/VRK1/BRDT/USP49/SMARCC2/ASF1A/ANP32D/NASP/MCM3AP/ING4/SET/CARM1/TBL1X/SUPT16H/SMARCA5/HINFP/SNCA/SMARCC1/EZH1/DAXX/TONSL/KAT6B/WDR5/GLYR1/ZMYND8/TAF7/L3MBTL1/KDM4A	89
MF	GO:0004298	threonine-type endopeptidase activity	12/7116	21/17697	0.08797	0.4031	0.3562	PSMB9/PSMB8/PSMA5/PSMB10/PSMA1/PSMA4/PSMB1/PSMB3/PSMB5/PSMA2/PSMB2/PSMB4	12
MF	GO:0004602	glutathione peroxidase activity	12/7116	21/17697	0.08797	0.4031	0.3562	ALOX5AP/MGST2/GSTP1/GPX7/GSTZ1/GPX3/GSTA1/GPX4/MGST1/PRDX6/MGST3/GPX1	12
MF	GO:0050750	low-density lipoprotein particle receptor binding	12/7116	21/17697	0.08797	0.4031	0.3562	APOE/LRPAP1/CLU/APOA5/AP2A1/HSP90B1/DNAJA1/SYT1/LANCL1/AP2M1/PICALM/SNX17	12
MF	GO:0070003	threonine-type peptidase activity	12/7116	21/17697	0.08797	0.4031	0.3562	PSMB9/PSMB8/PSMA5/PSMB10/PSMA1/PSMA4/PSMB1/PSMB3/PSMB5/PSMA2/PSMB2/PSMB4	12
MF	GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors	23/7116	45/17697	0.09087	0.4144	0.3662	HSPBAP1/JMJD6/ALKBH1/PHYH/TET2/KDM7A/EGLN1/KDM2A/ALKBH4/HIF1AN/PLOD1/EGLN3/KDM4B/FTO/KDM2B/KDM8/PLOD2/ALKBH8/JMJD4/ALKBH2/P4HA1/TET1/KDM4A	23
MF	GO:0005086	ARF guanyl-nucleotide exchange factor activity	11/7116	19/17697	0.09147	0.4144	0.3662	CYTH4/CYTH1/SEC61B/ARF4/ARFGEF1/IQSEC1/FBXO8/IQSEC2/IQSEC3/PSD4/PSD3	11
MF	GO:0016500	protein-hormone receptor activity	11/7116	19/17697	0.09147	0.4144	0.3662	ADIPOR1/LGR4/INSR/IGF1R/PAX8/ADIPOR2/LGR5/FSHR/RXFP2/LGR6/AMHR2	11
MF	GO:0051536	iron-sulfur cluster binding	31/7116	63/17697	0.09254	0.4161	0.3677	FECH/CISD2/NFU1/NFS1/ISCU/PRIM2/RSAD2/DPYD/ETFDH/ACO1/NUBPL/GLRX3/RFESD/ELP3/PPAT/CISD1/IREB2/FDX1/NDUFS1/RSAD1/RTEL1/ISCA1/ERCC2/POLD1/ISCA2/POLA1/NDUFS7/NDUFV2/AOX1/NDUFS2/CIAPIN1	31
MF	GO:0051540	metal cluster binding	31/7116	63/17697	0.09254	0.4161	0.3677	FECH/CISD2/NFU1/NFS1/ISCU/PRIM2/RSAD2/DPYD/ETFDH/ACO1/NUBPL/GLRX3/RFESD/ELP3/PPAT/CISD1/IREB2/FDX1/NDUFS1/RSAD1/RTEL1/ISCA1/ERCC2/POLD1/ISCA2/POLA1/NDUFS7/NDUFV2/AOX1/NDUFS2/CIAPIN1	31
MF	GO:0051010	microtubule plus-end binding	10/7116	17/17697	0.09483	0.4241	0.3748	CLIP1/PAFAH1B1/MAPRE1/MAPRE2/CKAP5/CLASP2/KIF2C/CLIP2/SKAP1/TTBK2	10
MF	GO:0019239	deaminase activity	17/7116	32/17697	0.09591	0.4241	0.3748	GNPDA1/CDADC1/ADARB1/APOBEC3G/APOBEC3C/APOBEC2/ZBP1/AMPD2/ADA/APOBEC3B/DCTD/ADAT2/CDA/AMPD3/ADAL/ADAR/ADAT1	17
MF	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity	57/7116	123/17697	0.09748	0.4241	0.3748	ATP6V0D2/ATP2B4/ABCC5/ATP1A1/ATP6AP1/ATP8A1/TIMM23B/PCYOX1/ATP6V1C1/TAP2/TAP1/ABCD4/ATP6V0C/CD320/ABCD3/SEC61B/TCIRG1/ABCB6/ATP6V1A/ATP4A/ABCA1/TIMM17A/ATP2C1/ABCB10/ATP6V1G3/ATP7B/ATP1B2/ATP6V1B2/ABCA5/TAPBP/ATP6V1D/ATP1B3/ABCB5/ATP6AP1L/ATP6V0E2/ATP1B1/ABCG1/ABCB4/ABCB11/ATP6V1G2/LMBRD1/TOMM20/ABCA7/ABCA11P/ABCC10/ATP2A2/RALBP1/SEC61G/ATP7A/ABCA6/FXYD2/ABCC3/ABCC4/ABCD1/ATP1A2/ATP12A/ABCB7	57
MF	GO:0004029	aldehyde dehydrogenase (NAD) activity	9/7116	15/17697	0.09788	0.4241	0.3748	ALDH3A2/ALDH9A1/ALDH1A1/ALDH7A1/ADH5/ALDH2/ALDH4A1/ALDH1L1/ALDH3A1	9
MF	GO:0005545	1-phosphatidylinositol binding	9/7116	15/17697	0.09788	0.4241	0.3748	SNX10/SCARB1/ZFYVE1/WDFY1/SCIN/EPB41/SYT1/SNX9/PICALM	9
MF	GO:0015929	hexosaminidase activity	9/7116	15/17697	0.09788	0.4241	0.3748	HEXB/NAGLU/GM2A/HEXA/NAGPA/HYAL2/NAGA/HYAL3/CEMIP	9
MF	GO:0017160	Ral GTPase binding	9/7116	15/17697	0.09788	0.4241	0.3748	RNF41/FLNA/RGL1/RGL3/MYO1C/RALGPS1/RALBP1/EXOC4/EXOC2	9
MF	GO:0072349	modified amino acid transmembrane transporter activity	9/7116	15/17697	0.09788	0.4241	0.3748	SLC22A4/SLC19A2/SLC22A5/SLC7A11/SLC1A4/SLC46A1/SLC25A32/CTNS/SLC22A16	9
MF	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process	9/7116	15/17697	0.09788	0.4241	0.3748	CASP6/CLC/CASP3/CASP8/CASP5/CASP7/CASP2/CASP1/CASP4	9
MF	GO:1990380	Lys48-specific deubiquitinase activity	9/7116	15/17697	0.09788	0.4241	0.3748	USP9X/CYLD/OTUD5/DESI2/USP27X/ATXN3/YOD1/USP7/USP19	9
MF	GO:0034450	ubiquitin-ubiquitin ligase activity	8/7116	13/17697	0.1004	0.4246	0.3752	UBE4B/UBE2K/UBR5/STUB1/PRPF19/ANAPC11/RBX1/PELI2	8
MF	GO:0008266	poly(U) RNA binding	16/7116	30/17697	0.101	0.4246	0.3752	KHDRBS1/HNRNPH1/DAZAP1/IFIT5/MCRS1/RBM3/HNRNPC/RBMS1/RBMS2/SSB/FMR1/DIS3L2/ATXN1/MSI2/PNPT1/PABPC4L	16
MF	GO:0004386	helicase activity	74/7116	163/17697	0.1013	0.4246	0.3752	HLTF/DDX21/ASCC3/MCM6/DDX60L/DDX20/GINS1/MCM2/SLFN11/DDX60/MOV10/CHD1/CHD2/RUVBL2/HELZ2/RUVBL1/DDX49/DDX58/SNRNP200/BTAF1/WRNIP1/DSCC1/XRCC5/CHD9/DDX19B/DHX9/GTF2F2/SMARCAD1/DHX8/MOV10L1/SMARCA1/RFC3/DDX3X/DDX24/SETX/DICER1/ACTR5/IFIH1/CHD6/HELZ/RAD54B/DDX1/DDX46/RECQL/DHX32/ERCC6L/GINS4/MCM5/FANCM/RTEL1/SUPV3L1/ERCC2/XRCC6/SHPRH/DDX18/DHX38/DDX27/NAV2/SMARCA5/DDX43/DDX54/MCM8/DDX10/DDX50/AQR/SKIV2L/DHX16/DDX55/RECQL4/ZRANB3/ERCC6L2/DDX31/UPF1/DDX52	74
MF	GO:0005324	long-chain fatty acid transporter activity	7/7116	11/17697	0.1019	0.4246	0.3752	SLC27A1/SLC27A3/FABP4/ABCD3/SLC27A2/FABP3/ABCD1	7
MF	GO:0016783	sulfurtransferase activity	7/7116	11/17697	0.1019	0.4246	0.3752	NFS1/MBIP/MOCS2/TSTD1/TST/MPST/MOCS3	7
MF	GO:0017166	vinculin binding	7/7116	11/17697	0.1019	0.4246	0.3752	SORBS3/TLN1/CTNNA1/ACTN1/DMD/PXN/DAG1	7
MF	GO:0019864	IgG binding	7/7116	11/17697	0.1019	0.4246	0.3752	FCGR1B/PIP/FCGR1A/FCGRT/FCGR3B/FCGR2C/FCGR2A	7
MF	GO:0030955	potassium ion binding	7/7116	11/17697	0.1019	0.4246	0.3752	ATP1A1/ADPRH/PKM/HDAC4/ATP1B1/KCNA4/ATP1A2	7
MF	GO:0043295	glutathione binding	7/7116	11/17697	0.1019	0.4246	0.3752	GSTP1/GSTM3/MGST1/MMACHC/GSS/GSTM4/LANCL1	7
MF	GO:0043422	protein kinase B binding	7/7116	11/17697	0.1019	0.4246	0.3752	BCL10/PINK1/SRSF5/TRAF6/CCDC88A/BAD/APPL1	7
MF	GO:0043560	insulin receptor substrate binding	7/7116	11/17697	0.1019	0.4246	0.3752	JAK2/PRKCD/INSR/IGF1R/GRB2/PRKCZ/PIK3CB	7
MF	GO:0019905	syntaxin binding	36/7116	75/17697	0.1043	0.4333	0.3828	STX7/PTPN2/RAB11A/HECTD3/SEC22B/STXBP5/STXBP1/SYPL1/UNC13B/STXBP2/VAMP3/ABL1/ABCA1/TMED10/DAPK1/BLOC1S6/DOC2B/LRRK2/SYT6/VPS18/NAPA/STX16/VPS52/NAPG/SYT13/SYPL2/SYT9/STX8/SYT1/SCFD1/SYT2/STXBP3/SNAP29/SYT4/SYT5/STXBP4	36
MF	GO:0035326	enhancer binding	61/7116	133/17697	0.1068	0.4421	0.3907	ZNF704/SPI1/IRF7/BHLHE40/NFYC/SMAD2/LDB1/NFKB1/REL/THRAP3/ATF4/RELA/ACTB/ZNF322/ZNF281/RUVBL2/ZBTB7B/MBD3/TCF12/RELB/NR1D2/HMGA1/AHR/RBBP4/CREB1/SIRT1/SFPQ/ELL3/MESP1/TAL1/ARX/CALCOCO1/HOXC4/HDAC2/HNRNPC/NFATC1/HMGB2/TIPARP/YY1/GZF1/ARNT/NFE2L2/NFE2L1/CLOCK/SMARCC2/ARNTL/BACH1/MSX1/HIVEP1/ESRRB/ZFP42/SMARCC1/ZBTB16/ACTL6A/HOXA7/NR1H4/PBX3/NR2F6/ATF6B/MEF2C/FOXH1	61
MF	GO:0072341	modified amino acid binding	42/7116	89/17697	0.1084	0.447	0.395	APPL2/SYT11/FCHO2/FOLR2/SCARB1/GSTP1/AXL/TLN1/ANXA9/RASGRP1/CD300LF/MARK1/HMGB1/GSTM3/SYT6/MGST1/FTCDNL1/MMACHC/ANXA6/GSS/GPR143/SLC46A1/TYMS/CD300A/GSTM4/DHFR/SYT13/SCIN/ANXA2P2/CPNE1/SYT9/SYTL2/GSDMC/SYT1/LANCL1/SYT2/SYT4/SYT5/ANXA2/ASAP1/APPL1/PLEKHN1	42
MF	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	35/7116	73/17697	0.1097	0.451	0.3985	ASAH1/ASRGL1/NTAN1/SIRT4/SIN3A/BTD/CAT/SIRT7/HDAC11/MIER1/WDYHV1/AGA/SIRT1/SIN3B/SUDS3/BRMS1L/HDAC10/VNN1/HDAC2/HDAC7/NACC2/SIRT5/HDAC4/PGLYRP4/NGLY1/GLS/ACER3/QRSL1/HDAC5/KLK3/ACR/MTA2/VNN3/ATXN3L/BRMS1	35
MF	GO:0035591	signaling adaptor activity	38/7116	80/17697	0.1121	0.4519	0.3993	SH2B2/STAM/SH3BP2/DOK2/SH2D3C/SH3RF1/TOB1/KHDRBS1/AKAP13/GAB1/CDC42SE2/NCK1/SHC1/CRK/TRADD/BLNK/HOMER1/DUSP19/MAVS/SH3BGR/ARHGAP6/GRB10/SHB/TRAT1/GRB2/LASP1/MPP7/ITSN2/PAG1/SKAP1/SH2D2A/SH2D1A/SLA2/CHN2/RUSC1/SOCS2/SKAP2/LAT	38
MF	GO:0051117	ATPase binding	38/7116	80/17697	0.1121	0.4519	0.3993	EZR/SNX10/PKD2/VCPKMT/ATOX1/UBE4B/RDX/DNAJB1/WFS1/NR1H2/RUVBL2/RUVBL1/TCIRG1/ABCA1/NSFL1C/CLPP/ATP6V1G3/RAC1/ATP1B2/METTL21A/SDF2L1/LCK/ATP1B3/FBL/ATP1B1/DNAJC10/DERL1/PEX19/NKD2/ATXN3/RAB3A/FXYD7/UBXN1/NUFIP1/HRC/SNTA1/SLN/ZNHIT6	38
MF	GO:0004033	aldo-keto reductase (NADP) activity	14/7116	26/17697	0.1122	0.4519	0.3993	KCNAB2/AKR1B1/RDH10/AKR1C3/AKR7A2/DHRS3/AKR7A3/AKR1A1/AKR1C1/RDH12/SPR/KCNAB1/AKR1B10/ALDH3A1	14
MF	GO:0004709	MAP kinase kinase kinase activity	14/7116	26/17697	0.1122	0.4519	0.3993	MAP3K8/MAP3K4/TAOK3/MAP3K12/RAF1/MAP3K6/MLKL/MAP3K11/MAP3K5/MOS/EGFR/MAP3K13/MAP3K1/MAP3K9	14
MF	GO:0030371	translation repressor activity	14/7116	26/17697	0.1122	0.4519	0.3993	SAMD4B/PURA/EIF4EBP2/RBM3/CPEB1/TYMS/CPEB3/IREB2/SHMT1/DHFR/FMR1/SAMD4A/PAIP2B/CPEB2	14
MF	GO:0030515	snoRNA binding	14/7116	26/17697	0.1122	0.4519	0.3993	DDX21/TSR1/NUDT1/ISG20/NUDT16L1/NOLC1/NHP2/GAR1/NUDT5/NUDT7/IMP4/NUFIP1/NUDT16/NOP10	14
MF	GO:0015144	carbohydrate transmembrane transporter activity	19/7116	37/17697	0.1127	0.4525	0.3998	SLC5A3/AQP9/SLC45A4/SLC23A2/PPBP/SLC45A3/SLC2A3/SLC2A6/SLC2A9/TMEM144/SLC2A8/SLC50A1/SLC5A4/SLC17A5/AQP3/SLC2A10/SLC5A10/SLC5A9/SLC5A2	19
MF	GO:0005048	signal sequence binding	23/7116	46/17697	0.1147	0.4586	0.4053	NUP214/NFKBIA/TNPO1/KCNIP2/POM121/NOLC1/IPO4/KDELR3/TOMM40L/PEX19/KDELR2/SRP14/TOMM20/SRP68/CEMIP/TIMM22/KPNA1/RANBP6/NPAP1/AP2M1/KPNB1/SEC61A2/POM121C	23
MF	GO:0008198	ferrous iron binding	13/7116	24/17697	0.1183	0.4701	0.4154	ACP5/FECH/ALKBH1/PHYH/TET2/FTL/ISCU/EGLN1/HAAO/FTO/SNCA/ALKBH2/DNAJC24	13
MF	GO:0051119	sugar transmembrane transporter activity	13/7116	24/17697	0.1183	0.4701	0.4154	SLC5A3/SLC23A2/PPBP/SLC45A3/SLC2A3/SLC2A6/SLC2A9/SLC2A8/SLC50A1/SLC5A4/SLC5A10/SLC5A9/SLC5A2	13
MF	GO:0050681	androgen receptor binding	22/7116	44/17697	0.1211	0.4797	0.4239	NCOA4/RAN/ARID5A/TRIM68/ZBTB7A/NCOA3/NSD1/GRIP1/WIPI1/PPARGC1A/KAT5/CCNE1/CALR/BRCA1/FHL2/TGFB1I1/RNF4/RB1/FOXP1/NRIP1/DAXX/FOXH1	22
MF	GO:0004518	nuclease activity	91/7116	205/17697	0.1241	0.4898	0.4328	RNASE2/ENPP2/TDP2/RNASEH2B/AGO2/DIS3L/RPP38/DNASE2B/ERCC4/SND1/RAD1/TSN/RNASE3/RNASE1/N4BP2/ANGEL1/ISG20/ISG20L2/XRN2/HELZ2/ENDOD1/ASTE1/SETMAR/TOE1/LACTB2/APTX/RNASE6/SAMHD1/DCP2/ZC3H12D/RPP25/ELAC1/USB1/MRPL44/DNASE1/SLFN13/CPSF3/RPP14/RNASEH1/DICER1/DCPS/AEN/POLG/LAS1L/XRN1/REXO2/XRCC1/EXOSC2/ERCC1/NME1/ZC3H12C/DDX1/RNASEL/GEN1/EXOSC7/RCL1/DCLRE1A/CNOT7/DNASE1L2/ERI3/FANCM/RPP40/ANKLE1/EXO1/POLD1/DXO/TATDN1/DCLRE1C/DIS3L2/RAD9A/EXOSC9/EXOSC3/TDP1/RPPH1/POP7/REXO4/DROSHA/APLF/ERN1/PNPT1/NUDT16/ENDOG/PNKP/DNASE2/FEN1/MBD4/PGAP1/TATDN3/ZRANB3/ENDOV/EXOSC5	91
MF	GO:0051537	2 iron, 2 sulfur cluster binding	12/7116	22/17697	0.1247	0.4908	0.4337	FECH/CISD2/ISCU/RFESD/CISD1/FDX1/NDUFS1/ISCA1/ISCA2/NDUFV2/AOX1/CIAPIN1	12
MF	GO:0015399	primary active transmembrane transporter activity	57/7116	125/17697	0.1271	0.4983	0.4403	ATP6V0D2/ATP2B4/ABCC5/ATP1A1/ATP6AP1/ATP8A1/TIMM23B/PCYOX1/ATP6V1C1/TAP2/TAP1/ABCD4/ATP6V0C/CD320/ABCD3/SEC61B/TCIRG1/ABCB6/ATP6V1A/ATP4A/ABCA1/TIMM17A/ATP2C1/ABCB10/ATP6V1G3/ATP7B/ATP1B2/ATP6V1B2/ABCA5/TAPBP/ATP6V1D/ATP1B3/ABCB5/ATP6AP1L/ATP6V0E2/ATP1B1/ABCG1/ABCB4/ABCB11/ATP6V1G2/LMBRD1/TOMM20/ABCA7/ABCA11P/ABCC10/ATP2A2/RALBP1/SEC61G/ATP7A/ABCA6/FXYD2/ABCC3/ABCC4/ABCD1/ATP1A2/ATP12A/ABCB7	57
MF	GO:0016853	isomerase activity	71/7116	158/17697	0.1283	0.5016	0.4432	ENOSF1/PGM3/FKBP2/GALM/GNPDA1/MIF/GALE/FKBP14/QSOX2/PIGK/PDIA3/PPIL1/PGAM1/PBLD/RPE/TPI1/DHRS9/HMGCS1/ECH1/CYP2J2/RPIA/QSOX1/RENBP/CYP2S1/FKBP5/ENOPH1/GSTZ1/MCEE/PUS7L/PMM2/ECI2/HSD17B4/ERP44/GSTA1/RPUSD2/GLCE/GPI/PUS1/PTGES3/PDIA6/PGM2/IDI1/PGM5/ECI1/FKBP11/TOP2B/FKBP9/EBPL/EHHADH/HPGDS/HYI/KATNA1/DCT/FKBP3/KATNAL1/PPIC/RPUSD3/SRR/TMX3/BCO2/PIN1/PDILT/GNE/TOP1/PUS7/PPWD1/TOP3B/PPIB/PIN4/TOP2A/AIP	71
MF	GO:0019003	GDP binding	35/7116	74/17697	0.1302	0.5071	0.4481	RAB9A/RAB42/GBP1/RAP1B/GNAI3/DYNC1LI1/TRIM23/RRAS/RAN/KRAS/RAB31/MIEF1/RAP2C/HRAS/RAP2B/RAP1A/RRAGD/RAB8A/RAB29/ARF1/RIT1/RAB5C/NRAS/RAB5A/RASL12/SUCLG2/RAB8B/RAB22A/RAB35/DIRAS1/RAB3B/RHOA/RAB27A/ARL8B/RAB28	35
MF	GO:0015299	solute:proton antiporter activity	11/7116	20/17697	0.1315	0.5108	0.4513	SLC11A1/SLC9A9/SLC9A1/CLCN3/SLC9A8/SLC9A7/LETM1/CLCN4/SLC9B2/CLCN5/SLC9C2	11
MF	GO:0015175	neutral amino acid transmembrane transporter activity	16/7116	31/17697	0.1333	0.5161	0.4561	SLC43A2/SFXN3/SLC36A1/SLC38A7/SLC7A11/SLC7A5/SLC1A4/SLC43A1/SLC38A1/SLC6A5/SLC7A8/SFXN1/SLC36A4/SLC25A38/SLC38A5/SLC38A9	16
MF	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups	102/7116	232/17697	0.1344	0.5183	0.458	LPCAT2/HADHB/ZDHHC20/NMT2/GPAM/MBOAT7/ACAA1/OSGEPL1/CERS2/ACSM5/SOAT1/HAT1/ELOVL5/SCP2/SAT1/LPGAT1/SUPT7L/KAT2B/PNPLA3/ZDHHC9/CPT2/NATD1/NAA20/NCOA3/OXSM/DBT/NAGS/EPC2/CERS5/NAA10/KAT7/SPTLC2/TAF5L/AGPAT3/PLA2G15/ZDHHC6/KAT8/TAF12/ELOVL7/DGAT2/NAA40/CERS4/ZDHHC5/TAF5/GNPNAT1/AGPAT4/NAT10/MCRS1/OSGEP/CRLS1/SPHK1/MBOAT2/KAT5/ZDHHC13/LCAT/ELP3/BRPF1/HHAT/DPF2/RSF1/CPT1A/PHF20/ZDHHC16/HADHA/YKT6/DLAT/TAF6L/NAA16/ING3/ZDHHC14/KANSL1L/CLOCK/AGPAT5/ACAA2/EPC1/KAT2A/PHF10/ZDHHC2/TAF9B/ZDHHC18/ALAS1/GNPAT/OGT/MCM3AP/NAT2/CROT/AGPAT1/NAA15/CHAT/TAZ/USP22/ELOVL6/NAT1/ZDHHC12/LPCAT1/TADA3/ZDHHC21/AGPAT2/KAT6B/WDR5/LPCAT3/NAA60	102
MF	GO:0140097	catalytic activity, acting on DNA	94/7116	213/17697	0.135	0.5191	0.4587	TDP2/CHRAC1/ASCC3/MCM6/ALKBH1/GINS1/MCM2/CHD1/DNASE2B/ERCC4/RAD1/NEIL2/UNG/ISG20/CHD2/RUVBL2/RUVBL1/SETMAR/POLD4/WRNIP1/APTX/TEP1/DSCC1/XRCC5/HMGA1/CHD9/DHX9/GTF2F2/POLD2/SMARCAD1/DNASE1/SMARCA1/POLI/TDG/RFC3/PTGES3/DDX3X/SETX/POLH/DICER1/ACTR5/FTO/POLG/CHD6/PCNA/XRCC1/ERCC1/NME1/TOP2B/RAD54B/DDX1/GEN1/PBRM1/RECQL/LIG4/ERCC6L/DCLRE1A/POLL/GINS4/DNASE1L2/DNMT3A/MCM5/RTEL1/SUPV3L1/ERCC2/EXO1/POLD1/TATDN1/XRCC6/DCLRE1C/RAD9A/TDP1/POLA1/POLA2/TERT/LIG3/NAV2/POLB/MCM8/APLF/TOP1/ALKBH2/POLE4/TOP3B/MGMT/ENDOG/DNASE2/FEN1/MBD4/RECQL4/ZRANB3/ENDOV/TOP2A/SMUG1	94
MF	GO:0016854	racemase and epimerase activity	10/7116	18/17697	0.1387	0.5316	0.4698	GALM/GALE/RPE/DHRS9/RENBP/MCEE/GLCE/HYI/SRR/GNE	10
MF	GO:0004540	ribonuclease activity	52/7116	114/17697	0.1392	0.532	0.4701	RNASE2/RNASEH2B/AGO2/DIS3L/RPP38/SND1/TSN/RNASE3/RNASE1/ANGEL1/ISG20/ISG20L2/XRN2/HELZ2/TOE1/LACTB2/RNASE6/SAMHD1/DCP2/RPP25/ELAC1/USB1/MRPL44/SLFN13/CPSF3/RPP14/RNASEH1/DICER1/DCPS/XRN1/REXO2/EXOSC2/RNASEL/EXOSC7/RCL1/CNOT7/ERI3/RPP40/EXO1/DIS3L2/EXOSC9/EXOSC3/RPPH1/POP7/DROSHA/ERN1/PNPT1/NUDT16/ENDOG/FEN1/ENDOV/EXOSC5	52
MF	GO:0140098	catalytic activity, acting on RNA	166/7116	386/17697	0.1402	0.534	0.4719	TRMT6/RNASE2/DDX21/JMJD6/PARS2/TDP2/MEPCE/ALKBH1/DDX60L/FTSJ1/DDX20/RNASEH2B/AGO2/DIS3L/DDX60/RPP38/NARS2/MOV10/METTL14/TRMT5/TRMT1/SND1/TSN/RNASE3/RNASE1/TYW3/ANGEL1/ISG20/ISG20L2/METTL3/XRN2/HELZ2/DDX49/DDX58/TFB1M/BCDIN3D/SNRNP200/DUS2/TOE1/PRIM2/LACTB2/LCMT2/LARS2/TRMT112/RNASE6/SAMHD1/DDX19B/DHX9/DCP2/POLR2L/TRMT61B/RPP25/ELAC1/NSUN2/DHX8/DALRD3/USB1/MOV10L1/MRPL44/SLFN13/TRMT1L/DTD1/CPSF3/RPP14/PUS1/POLR2H/DDX3X/DDX24/PTRHD1/RNASEH1/DICER1/DCPS/FBL/IARS2/ISY1/IFIH1/FTO/METTL1/XRN1/REXO2/METTL8/EXOSC2/FTSJ3/RAD54B/FDXACB1/DDX1/QTRT1/DDX46/RNASEL/PRPF8/DIMT1/CMTR1/POLR1C/ZCCHC4/WDR4/ALKBH8/EXOSC7/DHX32/RCL1/POLR2F/THUMPD2/POLR2D/TRMT11/TGS1/METTL15/CNOT7/RBMX2/POLR3E/THUMPD3/POLR2K/MARS2/ERI3/FANCM/RPP40/SUPV3L1/EXO1/MRM1/HARS2/DIS3L2/EXOSC9/DDX18/MTFMT/EXOSC3/DHX38/DDX27/YARS2/RPPH1/FBLL1/DARS2/POP7/DTD2/QRSL1/CMTR2/DROSHA/TERT/POLRMT/POLR2J2/DDX43/DDX54/CD3EAP/POLR3F/NT5C3A/DDX10/ERN1/DDX50/DUS1L/PNPT1/AQR/TRMT10C/POLR3GL/SKIV2L/DHX16/NUDT16/DDX55/NSUN6/ENDOG/POLR2I/AARS2/FEN1/POLR3K/ENDOV/EXOSC5/DDX31/WARS2/UPF1/DDX52	166
MF	GO:0032947	protein-containing complex scaffold activity	15/7116	29/17697	0.1412	0.5362	0.4738	NUP62/SH3RF1/G3BP2/AKAP13/NCK1/GRIP1/DEDD2/DUSP19/LRRK2/RGS14/CD3G/SHANK1/CARD10/CD3E/SHANK3	15
MF	GO:0061631	ubiquitin conjugating enzyme activity	19/7116	38/17697	0.1433	0.5422	0.4791	UBE2Z/UBE2N/UBE2Q2/UBE2K/UBE2S/UBE2D3/UBE2D2/UBE2L6/UBE2J1/UBE2W/UBE2E1/UBE2A/UBE2G2/UBE2E2/UBE2D4/UBE2C/UBE2G1/UBE2B/UBE3B	19
MF	GO:0045296	cadherin binding	143/7116	331/17697	0.1437	0.5422	0.4791	VASP/EZR/TAGLN2/ANXA1/CLIC1/LDHA/SNX1/EFHD2/TES/PDLIM1/PFKP/PLEC/FLNA/PACSIN2/ESYT2/PLIN3/STAT1/F11R/VCL/S100P/FXYD5/S100A11/RAN/GIGYF2/COBLL1/LYPLA2/PTPRO/TMOD3/BZW2/NOTCH3/LIMA1/PKM/CHMP4B/SND1/HDLBP/TWF2/TLN1/RDX/PCBP1/PFN1/DNAJB1/CTNNA1/PRDX1/LRRFIP1/CSNK1D/SWAP70/BZW1/CAST/MICALL1/HNRNPK/RUVBL1/BAIAP2/AHNAK/CAPG/PAICS/HSPA5/NCK1/EHD4/SFN/ENO1/PAK2/ALDOA/EMD/CTNNAL1/NUMB/CAPZA1/TBC1D2/MAPRE1/EHD1/IDH1/VAPB/SLK/EIF4H/NDRG1/SPTBN1/EVPL/CDH5/EIF4G2/STX5/CORO1B/DDX3X/MYH9/TNKS1BP1/PUF60/CNN2/ZC3HAV1/PDLIM5/CTNNA3/ATXN2L/SH3GL1/ATIC/MARK2/PRDX6/CKAP5/IST1/ARHGAP18/KTN1/EIF5/ZC3H15/CD2AP/YKT6/LASP1/FLNB/ARGLU1/PPP1CA/CCT8/EGFR/PKN2/CDH17/MPP7/TRIM29/FSCN1/PSEN1/SNX5/SH3GLB1/YWHAE/RPL24/EIF2A/CDH10/TMPO/PKP2/KIF5B/HSP90AB1/SPTBN2/TACSTD2/KLC2/PTPRH/EPS8L2/ANXA2/CDH3/RTN4/CDHR3/SNX9/GOLGA3/ASAP1/PICALM/CDH26/MACF1/NUDC/PTPRM/PTPRJ/BMPR2/SLC9A3R2	143
MF	GO:0016746	transferase activity, transferring acyl groups	115/7116	264/17697	0.1457	0.5446	0.4812	LPCAT2/QPCT/HADHB/ZDHHC20/NMT2/GPAM/MBOAT7/ACAA1/OSGEPL1/CERS2/ACSM5/SOAT1/MBOAT1/HAT1/ELOVL5/SCP2/SAT1/LPGAT1/SUPT7L/KAT2B/PNPLA3/LIPT1/ZDHHC9/CPT2/NATD1/HMGCS1/NAA20/NCOA3/OXSM/DBT/NAGS/EPC2/CERS5/NAA10/KAT7/SPTLC2/TAF5L/ACLY/AGPAT3/PLA2G15/ZDHHC6/KAT8/TAF12/ELOVL7/DGAT2/NAA40/CERS4/ZDHHC5/TAF5/GNPNAT1/AGPAT4/NAT10/MCRS1/OSGEP/CRLS1/SPHK1/MBOAT2/KAT5/ZDHHC13/LCAT/ELP3/TGM2/BRPF1/HHAT/DPF2/RSF1/CPT1A/PHF20/ZCCHC4/ZDHHC16/TMEM68/HADHA/YKT6/TGM5/DLAT/TAF6L/NAA16/ING3/ZDHHC14/KANSL1L/CLOCK/AGPAT5/ACAA2/EPC1/GGT7/KAT2A/CLYBL/PHF10/GGT5/ZDHHC2/TAF9B/ZDHHC18/ALAS1/EPB42/GNPAT/OGT/MCM3AP/NAT2/CROT/AGPAT1/NAA15/CHAT/TAZ/USP22/ELOVL6/NAT1/ZDHHC12/LPCAT1/TADA3/ZDHHC21/AGPAT2/KAT6B/WDR5/LPCAT3/NAA60	115
MF	GO:0004708	MAP kinase kinase activity	9/7116	16/17697	0.1462	0.5446	0.4812	MAP2K1/MAPKAPK3/LRRK2/MAPKAPK5/MAP2K2/MAPK1/MAP2K4/MAP2K5/MAP3K9	9
MF	GO:0008191	metalloendopeptidase inhibitor activity	9/7116	16/17697	0.1462	0.5446	0.4812	RARRES1/TIMP2/LXN/TIMP4/TIMP1/SPOCK2/WFIKKN1/COL4A3/SPOCK1	9
MF	GO:0003777	microtubule motor activity	39/7116	84/17697	0.1462	0.5446	0.4812	KLC1/DYNC1LI1/KIF9/KIF3B/DYNLL2/CENPE/KIFC3/APPBP2/KIF4A/KIF2A/KIF16B/BBS4/DNAI2/KIF24/DNAH17/KIF20B/DYNC2LI1/KIF13A/DYNLRB1/DYNLRB2/KIF27/DNAL4/DNAI1/KIF2C/KIF17/SMC3/WDR60/KIF1B/KIF5B/KLC4/DYNC1LI2/KLC2/DNAH10/KIF1C/KIF12/KLC3/DNAH8/DNAH2/KIF14	39
MF	GO:0046915	transition metal ion transmembrane transporter activity	18/7116	36/17697	0.1518	0.563	0.4975	SLC40A1/SLC11A1/MCOLN1/SLC25A37/SLC31A2/SLC25A28/SLC39A10/ATP2C1/SLC39A8/ATP7B/SLC39A13/SLC39A1/SLC39A7/SLC30A6/SLC39A12/ATP7A/SLC30A2/SLC30A10	18
MF	GO:0004707	MAP kinase activity	8/7116	14/17697	0.1539	0.563	0.4975	MAPK12/MAPK7/MAPK13/NLK/MAPK8/MAPK1/MAPK11/MAPK9	8
MF	GO:0005338	nucleotide-sugar transmembrane transporter activity	8/7116	14/17697	0.1539	0.563	0.4975	SLC35B4/SLC35D1/SLC35B1/SLC35A3/SLC35C1/SLC35A5/SLC35A2/SLC35D2	8
MF	GO:0045504	dynein heavy chain binding	8/7116	14/17697	0.1539	0.563	0.4975	DYNC1LI1/DNAL1/DNAI2/DYNC2LI1/DNAI1/WDR60/DYNC1LI2/TRIM58	8
MF	GO:0060229	lipase activator activity	8/7116	14/17697	0.1539	0.563	0.4975	GM2A/PLAA/CASP3/CCL5/APOA5/ARHGAP6/ARF1/CCL8	8
MF	GO:0070403	NAD+ binding	8/7116	14/17697	0.1539	0.563	0.4975	HADH/SIRT4/CRYL1/HPGD/SIRT7/SIRT1/GLUD1/SIRT5	8
MF	GO:0042626	ATPase activity, coupled to transmembrane movement of substances	52/7116	115/17697	0.1579	0.5638	0.4982	ATP6V0D2/ATP2B4/ABCC5/ATP1A1/ATP6AP1/ATP8A1/PCYOX1/ATP6V1C1/TAP2/TAP1/ABCD4/ATP6V0C/CD320/ABCD3/TCIRG1/ABCB6/ATP6V1A/ATP4A/ABCA1/ATP2C1/ABCB10/ATP6V1G3/ATP7B/ATP1B2/ATP6V1B2/ABCA5/TAPBP/ATP6V1D/ATP1B3/ABCB5/ATP6AP1L/ATP6V0E2/ATP1B1/ABCG1/ABCB4/ABCB11/ATP6V1G2/LMBRD1/ABCA7/ABCA11P/ABCC10/ATP2A2/RALBP1/ATP7A/ABCA6/FXYD2/ABCC3/ABCC4/ABCD1/ATP1A2/ATP12A/ABCB7	52
MF	GO:0043492	ATPase activity, coupled to movement of substances	52/7116	115/17697	0.1579	0.5638	0.4982	ATP6V0D2/ATP2B4/ABCC5/ATP1A1/ATP6AP1/ATP8A1/PCYOX1/ATP6V1C1/TAP2/TAP1/ABCD4/ATP6V0C/CD320/ABCD3/TCIRG1/ABCB6/ATP6V1A/ATP4A/ABCA1/ATP2C1/ABCB10/ATP6V1G3/ATP7B/ATP1B2/ATP6V1B2/ABCA5/TAPBP/ATP6V1D/ATP1B3/ABCB5/ATP6AP1L/ATP6V0E2/ATP1B1/ABCG1/ABCB4/ABCB11/ATP6V1G2/LMBRD1/ABCA7/ABCA11P/ABCC10/ATP2A2/RALBP1/ATP7A/ABCA6/FXYD2/ABCC3/ABCC4/ABCD1/ATP1A2/ATP12A/ABCB7	52
MF	GO:0000175	3'-5'-exoribonuclease activity	17/7116	34/17697	0.1609	0.5638	0.4982	DIS3L/ANGEL1/ISG20/ISG20L2/XRN2/TOE1/USB1/REXO2/EXOSC2/EXOSC7/CNOT7/ERI3/DIS3L2/EXOSC9/EXOSC3/PNPT1/EXOSC5	17
MF	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters	17/7116	34/17697	0.1609	0.5638	0.4982	RNASEH2B/AGO2/RPP38/RPP25/ELAC1/MRPL44/RPP14/RNASEH1/DICER1/RPP40/EXO1/RPPH1/POP7/DROSHA/NUDT16/FEN1/ENDOV	17
MF	GO:0004000	adenosine deaminase activity	7/7116	12/17697	0.1619	0.5638	0.4982	ADARB1/ZBP1/ADA/ADAT2/ADAL/ADAR/ADAT1	7
MF	GO:0004859	phospholipase inhibitor activity	7/7116	12/17697	0.1619	0.5638	0.4982	ANXA1/APOC1/ANXA3/SCGB1A1/ANXA2P2/ANXA2/PDC	7
MF	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	7/7116	12/17697	0.1619	0.5638	0.4982	SLC35B4/SLC35D1/SLC35B1/SLC35A3/SLC35A5/SLC35A2/SLC35D2	7
MF	GO:0016004	phospholipase activator activity	7/7116	12/17697	0.1619	0.5638	0.4982	GM2A/PLAA/CASP3/CCL5/ARHGAP6/ARF1/CCL8	7
MF	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	7/7116	12/17697	0.1619	0.5638	0.4982	GALM/GALE/RPE/RENBP/GLCE/HYI/GNE	7
MF	GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	7/7116	12/17697	0.1619	0.5638	0.4982	PTPMT1/SYNJ1/FIG4/SYNJ2/OCRL/INPP5K/INPP5F	7
MF	GO:1900750	oligopeptide binding	7/7116	12/17697	0.1619	0.5638	0.4982	GSTP1/GSTM3/MGST1/MMACHC/GSS/GSTM4/LANCL1	7
MF	GO:0005178	integrin binding	59/7116	132/17697	0.1669	0.5638	0.4982	IGF1/FN1/ICAM2/TSPAN4/LYN/ICAM3/ITGA5/GPNMB/S1PR3/PTPN2/ITGB7/ITGB5/SPP1/TIMP2/ACTN4/LAMB2/CXCL12/CD226/TLN1/ADAM15/ACTN1/NRG1/IL1B/CD151/ISG15/HMGB1/NISCH/FGF1/ICAM4/MYH9/LCP1/EMP2/FCER2/MADCAM1/ITGA2/ADAM22/VWF/ITGA3/MMP14/CALR/PXN/EGFR/ADAM17/JAM3/CDH17/ADAM9/LTBP4/COL4A3/TNXB/TGFBI/IBSP/CX3CL1/ITGB1BP1/CIB2/PTPRZ1/TSPAN8/PRKCA/CDH26/ADAM11	59
MF	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	45/7116	99/17697	0.1673	0.5638	0.4982	SPI1/BHLHE40/NFYC/NFKB1/REL/THRAP3/ATF4/RELA/ACTB/ZNF281/RUVBL2/MBD3/RELB/NR1D2/RBBP4/CREB1/SIRT1/SFPQ/TAL1/ARX/CALCOCO1/HOXC4/HDAC2/HNRNPC/NFATC1/YY1/GZF1/NFE2L2/NFE2L1/CLOCK/SMARCC2/ARNTL/BACH1/HIVEP1/ESRRB/ZFP42/SMARCC1/ZBTB16/ACTL6A/HOXA7/NR1H4/PBX3/NR2F6/ATF6B/MEF2C	45
MF	GO:0051539	4 iron, 4 sulfur cluster binding	20/7116	41/17697	0.1681	0.5638	0.4982	NFU1/ISCU/PRIM2/RSAD2/DPYD/ETFDH/ACO1/NUBPL/PPAT/IREB2/NDUFS1/RSAD1/RTEL1/ERCC2/POLD1/ISCA2/POLA1/NDUFS7/NDUFS2/CIAPIN1	20
MF	GO:0001223	transcription coactivator binding	12/7116	23/17697	0.1687	0.5638	0.4982	RELA/ZBTB49/AHR/CREB1/CDK9/VGLL4/NFATC1/TEAD2/PPARA/RORA/NR4A3/TERT	12
MF	GO:0030159	receptor signaling complex scaffold activity	12/7116	23/17697	0.1687	0.5638	0.4982	NUP62/G3BP2/NCK1/GRIP1/DEDD2/LRRK2/RGS14/CD3G/SHANK1/CARD10/CD3E/SHANK3	12
MF	GO:0015297	antiporter activity	39/7116	85/17697	0.1688	0.5638	0.4982	SLC8A1/SLC47A1/SLC22A4/SLC11A1/SLC9A9/SLC37A2/CLCN7/SLC37A4/SLC7A11/SLC9A1/SLC26A11/SLC7A6/CLCN3/SLC25A10/SLC35D1/SLC9A8/SLC25A5/SLC9A7/SLC26A8/SLC35E1/SLC4A5/SLC26A4/SLC41A1/SLC35C1/LETM1/SLC8A2/CLCN4/SLC25A16/SLC4A1/SLC24A4/SLC9B2/SLC24A2/SLC26A10/CLCN5/SLC8A3/SLC4A11/SLC9C2/SLC35D2/SLC4A3	39
MF	GO:0001540	amyloid-beta binding	36/7116	78/17697	0.1691	0.5638	0.4982	ITGAM/FPR2/APBA1/TLR2/LILRB2/MARCO/SCARB1/CD74/EPHB2/APOE/CST3/LDLRAD3/ITM2B/CD36/LRPAP1/INSR/TLR4/AGER/ITM2A/LDLR/LRP1/CLU/BACE2/ADRB2/ITGA2/FZD5/FZD4/TM2D1/APOA1/TREM2/IAPP/GSAP/PICALM/GRIA2/TLR6/DLGAP3	36
MF	GO:0003724	RNA helicase activity	36/7116	78/17697	0.1691	0.5638	0.4982	DDX21/DDX60L/DDX20/DDX60/MOV10/HELZ2/DDX49/DDX58/SNRNP200/DDX19B/DHX9/DHX8/MOV10L1/DDX3X/DDX24/IFIH1/RAD54B/DDX1/DDX46/DHX32/FANCM/SUPV3L1/DDX18/DHX38/DDX27/DDX43/DDX54/DDX10/DDX50/AQR/SKIV2L/DHX16/DDX55/DDX31/UPF1/DDX52	36
MF	GO:0000014	single-stranded DNA endodeoxyribonuclease activity	6/7116	10/17697	0.1697	0.5638	0.4982	ERCC4/SETMAR/XRCC1/ERCC1/DCLRE1C/ENDOG	6
MF	GO:0002162	dystroglycan binding	6/7116	10/17697	0.1697	0.5638	0.4982	VCL/DMD/FKRP/CLASP2/AGR3/DAG1	6
MF	GO:0004576	oligosaccharyl transferase activity	6/7116	10/17697	0.1697	0.5638	0.4982	DAD1/STT3A/RPN2/STT3B/TUSC3/DDOST	6
MF	GO:0010857	calcium-dependent protein kinase activity	6/7116	10/17697	0.1697	0.5638	0.4982	PINK1/MAPKAPK3/MAPKAPK5/MAPKAPK2/CAMK2A/MKNK2	6
MF	GO:0015651	quaternary ammonium group transmembrane transporter activity	6/7116	10/17697	0.1697	0.5638	0.4982	SLC22A4/SLC25A20/SLC22A5/SLC25A47/SLC25A45/SLC22A16	6
MF	GO:0016176	superoxide-generating NADPH oxidase activator activity	6/7116	10/17697	0.1697	0.5638	0.4982	SH3PXD2A/NCF4/NCF2/NCF1/PDGFB/NOXA1	6
MF	GO:0019203	carbohydrate phosphatase activity	6/7116	10/17697	0.1697	0.5638	0.4982	FBP1/PFKFB3/PFKFB4/PFKFB1/PFKFB2/G6PC	6
MF	GO:0031419	cobalamin binding	6/7116	10/17697	0.1697	0.5638	0.4982	MTR/CD320/MMAB/MMACHC/LMBRD1/TCN1	6
MF	GO:0043995	histone acetyltransferase activity (H4-K5 specific)	6/7116	10/17697	0.1697	0.5638	0.4982	KAT8/MCRS1/PHF20/KANSL1L/OGT/WDR5	6
MF	GO:0043996	histone acetyltransferase activity (H4-K8 specific)	6/7116	10/17697	0.1697	0.5638	0.4982	KAT8/MCRS1/PHF20/KANSL1L/OGT/WDR5	6
MF	GO:0046790	virion binding	6/7116	10/17697	0.1697	0.5638	0.4982	PTX3/CD209/TSG101/ANXA2P2/ANXA2/APCS	6
MF	GO:0046972	histone acetyltransferase activity (H4-K16 specific)	6/7116	10/17697	0.1697	0.5638	0.4982	KAT8/MCRS1/PHF20/KANSL1L/OGT/WDR5	6
MF	GO:0046974	histone methyltransferase activity (H3-K9 specific)	6/7116	10/17697	0.1697	0.5638	0.4982	SETDB2/SUV39H2/SETD5/SUV39H1/ASH1L/SETDB1	6
MF	GO:0050308	sugar-phosphatase activity	6/7116	10/17697	0.1697	0.5638	0.4982	FBP1/PFKFB3/PFKFB4/PFKFB1/PFKFB2/G6PC	6