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ID PMID Title PublicationDate abstract
11100535 [RS3PE syndrome: report of 11 cases]. 2000 Sep The RS3P syndrome or remitting seronegative symmetrical synovitis with pitting oedema, was described in 1985 by McCarty. The description refers to a rheumatologic set of symptoms with an acute commence, with no erosive lesions, with seronegativity, affecting more frequently to elderly males and showing an excellent prognosis. These characteristics make it possible to difference from the rheumatoid arthritis and from the rheumatic polymyalgia. We present eleven cases which confirm the good prognosis already described, but we suggest the possibility of this syndrome could be a manifestation or the beginning of other possible diseases.
11881371 [Ultrasound densitometry of the heel bone in the diagnosis of osseous tissue metabolic abn 2001 Sep The implication was studied of such factors as occurrence of the affliction, sex, inflammation activity, joint functional inadequacies, intake of steroids in the development of osteopenia and osteoporosis in patients with rheumatoid arthritis (RA). Determined in the above patients were RRF, SOS, BUA with the aid of the ultrasonic densitometer UBIS 5000 of the DMS (FRANCIUM) firm. Of the 42 examined patients, osteoporosis was identified in 28.5 percent, osteopenia in 45.3 percent of cases, the degree associated with RA duration, inflammation activity, function disorders of the joints favored by intensification of processes of osteal resorption in rheumatoid arthritis.
9263146 Financial and career losses due to rheumatoid arthritis: a pilot study. 1997 Aug OBJECTIVE: To use a novel method of estimating income loss associated with rheumatoid arthritis (RA). METHODS: For the 26 RA patients (16 female and 10 male, mean age 52.77 yrs) participating in our study, job histories were used to estimate earning potential based on the United States Department of Labor job analysis. To estimate current function, work samples were performed using the Valpar Instrument Battery. The tests include measures of motor coordination, finger dexterity, and manual dexterity. Databases were used to estimate current earning potential on the basis of these performance measures. RESULTS: Estimated earnings decreased from $18,409 to $13,900 per yr. Furthermore, it was estimated that the number of jobs patients could perform dropped from 11.5 million to 2.6 million. CONCLUSION: These preliminary estimates suggest that RA causes significant reductions in earning potential and in the number of jobs that can be performed. This methodology, using a small sample of patients, produced results consistent with larger population studies.
10573763 Antibiotics for the treatment of rheumatologic syndromes. 1999 Nov Design of rational therapy depends on knowledge of the causes of the disease, which is knowledge often lacking in rheumatology. There have been theories of infectious causes of many rheumatologic diseases but no proof. The seductive possibility of an infectious etiology has led to the use of antibiotics for treating these diseases. This article reviews the effectiveness of antibiotics against rheumatologic syndromes, including rheumatoid arthritis and Lyme disease.
9002038 Investigation of candidate disease susceptibility genes in rheumatoid arthritis: principle 1997 Jan It has been estimated that a number of non-HLA susceptibility loci exist in rheumatoid arthritis (RA), each making relatively small contributions (lambda s < 2). Previous approaches for whole genome screening are unlikely to be sufficiently sensitive to detect such loci. As the pathology of RA already indicates several molecules that may be of potential importance in disease susceptibility, we propose an alternative approach, targeting candidate genes directly. Highly polymorphic dinucleotide markers within a candidate gene sequence or close to the gene can be used as markers, and the selection of the most appropriate markers is discussed. RA sibling pair families from the Arthritis and Rheumatism Council National Repository (n = 200) are used in linkage analysis studies. The data generated are analyzed using sib pair analysis methods to examine evidence of linkage. The interpretation of such results is also discussed, in particular, minimizing the possibility of type I errors, and the interpretation of negative results.
10050460 [Changes in the dynamic surface tension of the blood and urine during the development of v 1998 Oct The condition was studied of the dynamic surface tension of biologic fluids in patients with rheumatoid arthritis using a method of maximum pressure in the vesicle with the aid of computerized tensiometer MPT-1 "Lauda" (Germany). Rise in indices of blood serum surface tension with diminution of the slope of tensiogram curves may suggest the development of pathology of the heart and liver, while increase in the same parameters of urine might be indicative of the coming nephropathy.
10967835 [Fatigue tibial fracture coexistent with severe degenerative changes of the knee in a pati 2000 The authors present a case of fatigue fracture of the proximal tibia with concurrent degenerative changes of the knee in a 53 year old patient with rheumatoid arthritis. The patient was treated surgically with a hinge-rotation prothesis. The procedure yielded pain relief, correction of the axis of the lower limb with progressive bone union.
9782807 Effect of satisfaction with one's abilities on positive and negative affect among individu 1998 Jun OBJECTIVE: The purpose of this study was to examine the effect that self-evaluation processes have on psychologic well-being among individuals with rheumatoid arthritis (RA). METHODS: The study used a longitudinal research design with 4 data collection points. Participants were 227 adults with recently diagnosed RA. Data were collected via mailed questionnaire and telephone interview. Two dimensions of psychologic well-being were assessed--positive affect and negative affect. RESULTS: We found that, among participants who viewed the abilities being evaluated as very important, greater satisfaction at time 1 was associated with less negative affect at time 2 and time 4. Satisfaction was not associated with positive affect at any of the time points, however. CONCLUSION: Study findings indicate that dissatisfaction with illness-related abilities can exacerbate psychologic distress. The findings also highlight the need for research examining the role that positive affect plays in adaptation to RA.
15038238 Taking action on arthritis. 1999 Apr The statistics regarding arthritis are mind boggling: one out of every six Americans have arthritis. In New Jersey, more than one million people are affected by arthritis diseases. The condition costs the U.S. economy $65 billion annually in medical care and lost wages. The Centers for Disease Control and Prevention (CDC) projects that in the year 2020, one in five Americans will have arthritis--an estimated 59.4 million people. Increasing awareness of this disease among physicians is a necessity.
10473517 Urinary excretion of thiol compounds in patients with rheumatoid arthritis. 1999 Sep The objective of the present study was to assess the excretion of urinary thiol compounds in patients with active and inactive rheumatoid arthritis (RA). Urinary thiol compounds were measured by the method of Kokonov (M. T. Kokonov, Lab. Delo 5:273-276, 1965) in 51 outpatients with active and inactive RA. Those with active disease had significantly higher levels of urinary thioamine excretion.
11419085 [Use of magnetosorbents in the immunodiagnosis and therapy of systemic lupus erythematosus 2001 The authors present new technology of producing immobilized granulated antigenic magnetosorbents (MS) using collagen type II, IgG, denaturated DNA and cardiolipin which were employed in enzyme immunoassay for detection of specific antibodies in the blood of patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Due to high capacity, MS demonstrated effectiveness in early diagnosis, prognosis of RA and SLE as well as in control over the treatment effects. As shown in in vitro experiments, MS have high selective capacity and atraumaticity for blood corpuscles. MS can be sterilized, regenerated and reused which is a great advantage.
10205553 Rheumatology. Part 2: The role of medication. 1999 Feb Rheumatoid arthritis is a chronic, long-term inflammatory disease. Symptom relief can be achieved with analgesia and NSAIDs. The only way to influence its progress is by administering disease-modifying anti-rheumatic drugs.
10205541 Rheumatology. Part 3: The role of surgery. 1999 Mar Surgery can relieve the pain of some patients with rheumatoid arthritis. Caring for RA patients undergoing surgery is a multidisciplinary task. Nurses have a major role to play in pre-operative, peri-operative and postoperative care.
10599348 Pyridinium crosslinks excretion in patients with rheumatoid arthritis. Correlation with di 1999 In patients with rheumatoid arthritis, significant positive correlations were found between urinary pyridinium crosslinks and C-reactive protein (CRP), erythrocyte sedimentation rate (ESR) and articular index. Also an inverse correlation was observed between pyridinium crosslinks excretion and grip strength. Glucocorticoid therapy, equivalent to daily doses of 7.5 mg of prednisolone or less, did not appear to have deleterious effect on bone metabolism in these patients as measured by urinary pyridinium crosslinks.
9377029 [Clinical and immunologic criteria of the activity of different variants of the course of 1997 Sep Clinical and immunological studies were carried out in 24 IgM-RF seropositive and 10 seronegative patients with rheumatoid arthritis (RA). Manifest disorders of microcirculation were noted in the examinees, which was confirmed by changes in platelet hemostasis, detection of antibodies to cardiolipins and of Von Willebrandt's factor antigen, and a high level of circulating immune complexes. Analysis of laboratory and immunological findings showed an association of extraarticular symptoms of RA and detection of anticardiolipin antibodies and Von Willebrandt's factor antigen. The activity of the pathological process correlated with the time course of these parameters.
10587551 Spontaneous ambulatory activity as a quantifiable outcome measure for rheumatoid arthritis 1999 Dec OBJECTIVE: To validate the objective monitoring of ambulatory activity as an outcome measure for rheumatoid arthritis (RA). METHODS: We have compared ambulatory activity to a range of currently favoured outcome measures, ranging from subjective opinions to X-ray damage, in a population of 93 RA sufferers. RESULTS: Correlations were stronger with measures of joint damage and disability, and less strong with measures of disease activity. Sensitivity to change was good. Three different interventions were compared for the quantity of the response, and the results agree with clinical experience, with steroid injection of the knee and use of non-steroidal anti-inflammatory drugs (NSAIDs) having a similar response and the provision of surgical shoes producing a more modest increase in ambulation. CONCLUSION: The measurement of ambulatory activity has validity for RA assessment. It provides different but related data to the currently used measures. It is objective, relevant, quantifiable and of unlimited scale. It could be used to quantify interventions aimed at increasing ambulation, in carefully constructed studies.
10420834 [Epidemiology, manifestations and complications of chronic polyarthritis]. 1999 Jun 1 Rheumatoid arthritis is an inflammatory systemic disease mainly affecting the joints. Frequent extra-articular manifestations are often recognized too late. Particularly the skin, the cardiovascular system, the kidneys, the eyes, the gastrointestinal tract, the liver, the nervous system and the blood may be involved. Examples of important complications affecting different organs are bacterial infections, AA-amyloidosis and hyperviscosity syndrome. Current data on the different disease manifestations and complications provide the basis for the assessment of the morbidity and mortality relevant for insurance purposes.
11269536 Scintigraphic evaluation of synovial inflammation in rheumatoid arthritis with (99m)techne 2001 Feb The aim of this study was to investigate whether (99m)technetium-labelled polyclonal human immunoglobulin G (99mTc-IgG) scintigraphy reflects synovial inflammation in patients with rheumatoid arthritis (RA). We evaluated 29 patients with RA for this reason and found a highly significant correlation between total scintigraphic scores and total tenderness scores (r = 0.781, P < 0.001). A significant correlation was also found between 99mTc-IgG scintigraphic scores and tenderness in all joints other than the shoulders. The 99mTc-IgG scintigraphy had a sensitivity of 69% and specificity of 88% in cases with tenderness and 72% and 81%, respectively, in cases with swelling. Total scintigraphic scores were correlated with serum levels of C-reactive protein (r = 0.401, P < 0.05) but not with erythrocyte sedimentation rate (r = 0.149, P > 0.05). The correlation between disease activity scores and total scintigraphic scores was also found to be significant (r = 0.812, P < 0.001). We suggest that 99mTc-IgG scintigraphy is a reliable and objective method in detecting synovial activity and can be appropriate for observing disease prognosis in clinical trials with RA.
10868018 [Prospective multicenter observational study of early rheumatoid arthritis--prognostic fac 2000 Apr The aim of a new prospective, multicenter trial on early rheumatoid arthritis is to evaluate parameters of potential relevance for the prediction of an erosive disease course. The integration of general practitioners, rheumatologists, arthritis care units and experimental research groups in a network structure is intended to improve the cooperation between basic and clinical research as well as the treatment of the patients. The final goal is to identify new parameters that may improve an early stratification of patients into the appropriate treatment areas.
9465378 [Patient-centered evaluation of illness outcome in musculoskeletal diseases: model of illn 1997 Oct Musculoskeletal conditions usually cause pain, physical, psychological and social disability, and consequently reduce a patient's quality of life. Nowadays, it is generally accepted that patients are truly capable to assess disease consequences, if they are questioned with appropriate instruments. Models of disease and the disabling process provide the conceptual background for the measurement of disease consequences. To date, standardized assessment of outcomes with psychometrically sound instruments is commonplace in clinical trials, clinical epidemiology, economic studies, and health services research. However, standardized assessment tools are not yet widely used in clinical practice.