RA burden
| dicators | location_type | location_level | Counts_1990 | Counts_2021 | ASR_1990 | ASR_2021 | % Change in counts | AAPC in ASR | AAPC P-value | |
|---|---|---|---|---|---|---|---|---|---|---|
| Incidence | Global | Global | 488269 (435015 to 545895) | 1000319 (902687 to 1114213) | 10.42 (9.32 to 11.64) | 11.8 (10.64 to 13.12) | 105 (98 to 111) | 0.406 (0.388 to 0.424) | <0.001 | |
| Incidence | SDI | High SDI | 159835 (144136 to 177741) | 255315 (231186 to 282039) | 15.87 (14.3 to 17.64) | 16.88 (15.44 to 18.47) | 60 (55 to 64) | 0.206 (0.166 to 0.246) | <0.001 | |
| Incidence | SDI | High-middle SDI | 101601 (89922 to 114554) | 190166 (169306 to 213515) | 9.36 (8.29 to 10.55) | 11.66 (10.43 to 12.97) | 87 (78 to 98) | 0.712 (0.693 to 0.731) | <0.001 | |
| Incidence | SDI | Middle SDI | 142436 (124527 to 161709) | 321824 (287295 to 361682) | 9.72 (8.61 to 10.95) | 11.9 (10.67 to 13.38) | 126 (114 to 139) | 0.654 (0.639 to 0.668) | <0.001 | |
| Incidence | SDI | Low-middle SDI | 65828 (57842 to 75284) | 180057 (160663 to 202101) | 7.88 (6.97 to 8.93) | 10.49 (9.36 to 11.78) | 174 (164 to 182) | 0.934 (0.913 to 0.954) | <0.001 | |
| Incidence | SDI | Low SDI | 18210 (15885 to 20960) | 52398 (46046 to 59971) | 5.63 (4.99 to 6.39) | 7.04 (6.27 to 7.92) | 188 (183 to 193) | 0.726 (0.705 to 0.746) | <0.001 | |
| Incidence | GBD regions | Andean Latin America | 4413 (3873 to 4943) | 14555 (13019 to 16096) | 13.57 (12.25 to 15.03) | 21.72 (19.62 to 23.94) | 230 (208 to 250) | 1.531 (1.474 to 1.589) | <0.001 | |
| Incidence | GBD regions | Australasia | 4645 (4172 to 5142) | 9766 (8711 to 10894) | 20.63 (18.5 to 22.93) | 23.01 (20.53 to 25.58) | 110 (98 to 123) | 0.352 (0.325 to 0.379) | <0.001 | |
| Incidence | GBD regions | Caribbean | 2059 (1827 to 2330) | 4174 (3757 to 4620) | 6.57 (5.94 to 7.32) | 8.18 (7.4 to 9.06) | 103 (91 to 115) | 0.709 (0.686 to 0.732) | <0.001 | |
| Incidence | GBD regions | Central Asia | 4081 (3535 to 4673) | 9153 (8152 to 10188) | 6.48 (5.75 to 7.26) | 9.28 (8.3 to 10.27) | 124 (109 to 140) | 1.167 (1.131 to 1.203) | <0.001 | |
| Incidence | GBD regions | Central Europe | 11988 (10646 to 13528) | 14882 (13269 to 16674) | 8.74 (7.73 to 9.82) | 10.54 (9.31 to 11.82) | 24 (20 to 29) | 0.604 (0.588 to 0.621) | <0.001 | |
| Incidence | GBD regions | Central Latin America | 20439 (18098 to 22838) | 53218 (47958 to 58971) | 16.89 (15.1 to 18.86) | 20.11 (18.11 to 22.31) | 160 (149 to 171) | 0.564 (0.548 to 0.58) | <0.001 | |
| Incidence | GBD regions | Central Sub-Saharan Africa | 1864 (1636 to 2122) | 5940 (5219 to 6699) | 5.33 (4.8 to 5.95) | 6.35 (5.72 to 7.08) | 219 (207 to 230) | 0.561 (0.529 to 0.592) | <0.001 | |
| Incidence | GBD regions | East Asia | 131599 (114817 to 150105) | 255036 (223780 to 291265) | 11.52 (10.12 to 13.06) | 13.61 (12.08 to 15.42) | 94 (80 to 110) | 0.544 (0.527 to 0.561) | <0.001 | |
| Incidence | GBD regions | Eastern Europe | 16621 (14492 to 18778) | 19118 (16896 to 21498) | 6.84 (5.93 to 7.78) | 8.28 (7.25 to 9.34) | 15 (10 to 20) | 0.619 (0.602 to 0.636) | <0.001 | |
| Incidence | GBD regions | Eastern Sub-Saharan Africa | 5570 (4857 to 6430) | 15232 (13299 to 17531) | 4.88 (4.35 to 5.51) | 5.45 (4.9 to 6.13) | 173 (168 to 179) | 0.361 (0.334 to 0.387) | <0.001 | |
| Incidence | GBD regions | High-income Asia Pacific | 35873 (31332 to 41372) | 43684 (38485 to 49491) | 17.52 (15.28 to 20.04) | 15.95 (14.22 to 17.89) | 22 (16 to 28) | -0.29 (-0.323 to -0.257) | <0.001 | |
| Incidence | GBD regions | High-income North America | 48282 (44135 to 52996) | 92413 (84224 to 102220) | 15.49 (14.2 to 16.92) | 18.53 (17.09 to 20.21) | 91 (86 to 97) | 0.58 (0.533 to 0.627) | <0.001 | |
| Incidence | GBD regions | North Africa and Middle East | 11090 (9534 to 12923) | 35193 (30737 to 39521) | 3.75 (3.27 to 4.28) | 5.52 (4.84 to 6.21) | 217 (199 to 237) | 1.259 (1.234 to 1.284) | <0.001 | |
| Incidence | GBD regions | Oceania | 124 (102 to 149) | 329 (275 to 386) | 2.19 (1.84 to 2.58) | 2.56 (2.2 to 2.97) | 165 (151 to 180) | 0.514 (0.486 to 0.543) | <0.001 | |
| Incidence | GBD regions | South Asia | 76802 (67462 to 87625) | 234511 (207213 to 266928) | 10.02 (8.79 to 11.43) | 13.77 (12.15 to 15.66) | 205 (194 to 215) | 1.038 (1.003 to 1.074) | <0.001 | |
| Incidence | GBD regions | Southeast Asia | 12099 (10417 to 14221) | 31154 (27367 to 35740) | 3.16 (2.76 to 3.64) | 4.23 (3.73 to 4.81) | 157 (142 to 174) | 0.939 (0.914 to 0.964) | <0.001 | |
| Incidence | GBD regions | Southern Latin America | 4516 (4024 to 5030) | 11285 (10211 to 12405) | 9.44 (8.41 to 10.52) | 14.75 (13.28 to 16.19) | 150 (138 to 164) | 1.451 (1.43 to 1.472) | <0.001 | |
| Incidence | GBD regions | Southern Sub-Saharan Africa | 6543 (5701 to 7411) | 10579 (9299 to 11862) | 14.4 (12.74 to 16.12) | 13.18 (11.72 to 14.74) | 62 (55 to 69) | -0.29 (-0.312 to -0.268) | <0.001 | |
| Incidence | GBD regions | Tropical Latin America | 11505 (9576 to 13400) | 18330 (15761 to 20894) | 7.56 (6.42 to 8.72) | 7.61 (6.53 to 8.71) | 59 (51 to 71) | -0.003 (-0.061 to 0.056) | 0.931 | |
| Incidence | GBD regions | Western Europe | 74241 (67131 to 82453) | 109230 (98399 to 121128) | 15.49 (13.98 to 17.19) | 17.36 (15.74 to 19.19) | 47 (43 to 51) | 0.365 (0.343 to 0.386) | <0.001 | |
| Incidence | GBD regions | Western Sub-Saharan Africa | 3915 (3280 to 4697) | 12534 (10472 to 14865) | 2.79 (2.38 to 3.25) | 3.45 (2.99 to 3.95) | 220 (212 to 229) | 0.686 (0.661 to 0.712) | <0.001 | |
| Incidence | countries / territoriesc | Afghanistan | 224 (190 to 262) | 889 (737 to 1041) | 2.75 (2.37 to 3.18) | 3.35 (2.88 to 3.8) | 296 (261 to 335) | 0.625 (0.571 to 0.679) | <0.001 | |
| Incidence | countries / territoriesc | Albania | 150 (127 to 178) | 269 (233 to 311) | 5.06 (4.32 to 5.87) | 8.39 (7.29 to 9.65) | 79 (62 to 101) | 1.649 (1.543 to 1.754) | <0.001 | |
| Incidence | countries / territoriesc | Algeria | 541 (452 to 637) | 1781 (1514 to 2069) | 2.56 (2.19 to 2.97) | 3.98 (3.42 to 4.6) | 229 (198 to 266) | 1.438 (1.424 to 1.452) | <0.001 | |
| Incidence | countries / territoriesc | American Samoa | 1 (1 to 2) | 2 (2 to 2) | 3.34 (2.81 to 3.92) | 4.16 (3.57 to 4.82) | 43 (30 to 59) | 0.703 (0.664 to 0.742) | <0.001 | |
| Incidence | countries / territoriesc | Andorra | 5 (4 to 6) | 10 (8 to 11) | 7.96 (6.81 to 9.16) | 8.88 (7.58 to 10.18) | 100 (83 to 119) | 0.352 (0.332 to 0.372) | <0.001 | |
| Incidence | countries / territoriesc | Angola | 348 (304 to 396) | 1404 (1223 to 1588) | 5.31 (4.75 to 5.87) | 6.72 (6.06 to 7.45) | 303 (282 to 325) | 0.765 (0.735 to 0.796) | <0.001 | |
| Incidence | countries / territoriesc | Antigua and Barbuda | 4 (3 to 4) | 9 (8 to 10) | 6.66 (5.99 to 7.48) | 9.15 (8.22 to 10.2) | 138 (121 to 158) | 1.038 (0.991 to 1.084) | <0.001 | |
| Incidence | countries / territoriesc | Argentina | 2663 (2357 to 2983) | 5850 (5266 to 6462) | 8.27 (7.3 to 9.25) | 11.74 (10.55 to 12.98) | 120 (106 to 135) | 1.137 (1.114 to 1.16) | <0.001 | |
| Incidence | countries / territoriesc | Armenia | 128 (108 to 153) | 191 (163 to 217) | 3.79 (3.21 to 4.47) | 5.66 (4.86 to 6.51) | 49 (36 to 64) | 1.305 (1.262 to 1.347) | <0.001 | |
| Incidence | countries / territoriesc | Australia | 3690 (3322 to 4099) | 8045 (7189 to 9012) | 19.62 (17.61 to 21.74) | 22.6 (20.03 to 25.14) | 118 (103 to 134) | 0.454 (0.423 to 0.484) | <0.001 | |
| Incidence | countries / territoriesc | Austria | 1408 (1275 to 1561) | 1872 (1694 to 2098) | 14.92 (13.4 to 16.59) | 15.41 (13.75 to 17.24) | 33 (25 to 41) | 0.101 (0.067 to 0.135) | <0.001 | |
| Incidence | countries / territoriesc | Azerbaijan | 231 (193 to 278) | 486 (411 to 576) | 3.32 (2.78 to 3.94) | 4.2 (3.58 to 4.96) | 110 (94 to 129) | 0.766 (0.73 to 0.802) | <0.001 | |
| Incidence | countries / territoriesc | Bahamas | 15 (13 to 18) | 36 (32 to 40) | 6.93 (6.17 to 7.73) | 8.71 (7.81 to 9.68) | 136 (118 to 158) | 0.756 (0.715 to 0.797) | <0.001 | |
| Incidence | countries / territoriesc | Bahrain | 30 (24 to 37) | 182 (157 to 209) | 5.84 (5.06 to 6.73) | 9.84 (8.69 to 11.15) | 512 (427 to 607) | 1.69 (1.625 to 1.756) | <0.001 | |
| Incidence | countries / territoriesc | Bangladesh | 4114 (3533 to 4773) | 13104 (11432 to 14813) | 5.18 (4.58 to 5.89) | 8.05 (7.07 to 9.03) | 219 (197 to 248) | 1.436 (1.402 to 1.469) | <0.001 | |
| Incidence | countries / territoriesc | Barbados | 29 (26 to 32) | 54 (49 to 60) | 9.98 (9.03 to 10.97) | 13.44 (12.19 to 14.84) | 88 (74 to 105) | 0.962 (0.93 to 0.995) | <0.001 | |
| Incidence | countries / territoriesc | Belarus | 461 (386 to 539) | 702 (604 to 817) | 4.1 (3.43 to 4.77) | 6.32 (5.42 to 7.38) | 52 (41 to 65) | 1.406 (1.362 to 1.45) | <0.001 | |
| Incidence | countries / territoriesc | Belgium | 1754 (1574 to 1941) | 2432 (2185 to 2712) | 13.98 (12.45 to 15.64) | 15.55 (13.78 to 17.37) | 39 (31 to 48) | 0.338 (0.313 to 0.363) | <0.001 | |
| Incidence | countries / territoriesc | Belize | 9 (8 to 10) | 35 (30 to 40) | 6.53 (5.83 to 7.32) | 8.78 (7.77 to 9.85) | 302 (272 to 335) | 0.95 (0.919 to 0.981) | <0.001 | |
| Incidence | countries / territoriesc | Benin | 94 (79 to 114) | 352 (296 to 416) | 2.96 (2.56 to 3.44) | 3.64 (3.15 to 4.15) | 272 (251 to 295) | 0.671 (0.642 to 0.7) | <0.001 | |
| Incidence | countries / territoriesc | Bermuda | 5 (5 to 6) | 10 (9 to 12) | 7.86 (6.98 to 8.82) | 10.7 (9.46 to 12.07) | 102 (84 to 121) | 1.005 (0.976 to 1.034) | <0.001 | |
| Incidence | countries / territoriesc | Bhutan | 35 (30 to 41) | 96 (84 to 109) | 8.46 (7.43 to 9.49) | 13.26 (11.73 to 14.86) | 176 (155 to 199) | 1.462 (1.417 to 1.508) | <0.001 | |
| Incidence | countries / territoriesc | Bolivia (Plurinational State of) | 526 (459 to 602) | 1922 (1720 to 2151) | 11.08 (9.97 to 12.33) | 17.23 (15.63 to 19.11) | 265 (241 to 292) | 1.438 (1.414 to 1.462) | <0.001 | |
| Incidence | countries / territoriesc | Bosnia and Herzegovina | 418 (365 to 474) | 529 (467 to 599) | 8.64 (7.57 to 9.76) | 12.75 (11.18 to 14.35) | 27 (16 to 38) | 1.294 (1.123 to 1.465) | <0.001 | |
| Incidence | countries / territoriesc | Botswana | 72 (62 to 83) | 239 (209 to 272) | 7.74 (6.9 to 8.67) | 10.14 (9.02 to 11.36) | 232 (208 to 261) | 0.865 (0.825 to 0.906) | <0.001 | |
| Incidence | countries / territoriesc | Brazil | 11199 (9317 to 13034) | 17216 (14760 to 19736) | 7.53 (6.39 to 8.68) | 7.4 (6.31 to 8.47) | 54 (45 to 65) | -0.085 (-0.137 to -0.033) | 0.001 | |
| Incidence | countries / territoriesc | Brunei Darussalam | 20 (17 to 23) | 67 (60 to 75) | 10.88 (9.77 to 12.12) | 13.91 (12.52 to 15.42) | 231 (202 to 265) | 0.795 (0.772 to 0.818) | <0.001 | |
| Incidence | countries / territoriesc | Bulgaria | 479 (413 to 555) | 504 (434 to 575) | 4.94 (4.18 to 5.76) | 6.27 (5.42 to 7.22) | 5 (-2 to 13) | 0.762 (0.727 to 0.796) | <0.001 | |
| Incidence | countries / territoriesc | Burkina Faso | 182 (155 to 215) | 548 (457 to 648) | 2.85 (2.47 to 3.28) | 3.4 (2.96 to 3.92) | 200 (182 to 220) | 0.577 (0.552 to 0.602) | <0.001 | |
| Incidence | countries / territoriesc | Burundi | 156 (135 to 178) | 413 (358 to 478) | 4.61 (4.13 to 5.23) | 4.94 (4.42 to 5.51) | 165 (152 to 178) | 0.225 (0.189 to 0.261) | <0.001 | |
| Incidence | countries / territoriesc | Cabo Verde | 8 (6 to 9) | 22 (19 to 26) | 2.95 (2.51 to 3.4) | 3.95 (3.41 to 4.55) | 195 (170 to 226) | 0.951 (0.925 to 0.977) | <0.001 | |
| Incidence | countries / territoriesc | Cambodia | 203 (174 to 238) | 695 (609 to 797) | 2.78 (2.43 to 3.17) | 4.4 (3.87 to 4.97) | 242 (217 to 272) | 1.486 (1.473 to 1.5) | <0.001 | |
| Incidence | countries / territoriesc | Cameroon | 253 (211 to 298) | 981 (819 to 1160) | 3.42 (2.94 to 3.95) | 4.08 (3.55 to 4.69) | 288 (269 to 313) | 0.572 (0.517 to 0.626) | <0.001 | |
| Incidence | countries / territoriesc | Canada | 4695 (4420 to 4966) | 10898 (10177 to 11515) | 15.25 (14.42 to 16.07) | 20.74 (19.64 to 21.71) | 132 (122 to 143) | 1.001 (0.972 to 1.03) | <0.001 | |
| Incidence | countries / territoriesc | Central African Republic | 104 (93 to 117) | 236 (209 to 265) | 5.74 (5.22 to 6.36) | 5.97 (5.39 to 6.57) | 127 (116 to 140) | 0.124 (0.097 to 0.152) | <0.001 | |
| Incidence | countries / territoriesc | Chad | 105 (88 to 125) | 323 (269 to 386) | 2.58 (2.22 to 2.99) | 2.88 (2.5 to 3.31) | 208 (193 to 228) | 0.351 (0.328 to 0.373) | <0.001 | |
| Incidence | countries / territoriesc | Chile | 1524 (1355 to 1704) | 4893 (4369 to 5471) | 12.69 (11.39 to 14.05) | 21.64 (19.52 to 24.14) | 221 (194 to 247) | 1.742 (1.716 to 1.768) | <0.001 | |
| Incidence | countries / territoriesc | China | 127826 (111477 to 145914) | 247307 (216205 to 282998) | 11.59 (10.15 to 13.15) | 13.7 (12.12 to 15.55) | 93 (80 to 109) | 0.544 (0.529 to 0.559) | <0.001 | |
| Incidence | countries / territoriesc | Colombia | 2426 (2120 to 2748) | 7090 (6382 to 7841) | 9.03 (8.07 to 10.05) | 13.18 (11.83 to 14.63) | 192 (168 to 217) | 1.238 (1.196 to 1.279) | <0.001 | |
| Incidence | countries / territoriesc | Comoros | 14 (12 to 17) | 37 (33 to 42) | 4.96 (4.42 to 5.66) | 5.84 (5.21 to 6.55) | 160 (144 to 175) | 0.527 (0.506 to 0.547) | <0.001 | |
| Incidence | countries / territoriesc | Congo | 109 (96 to 123) | 391 (347 to 445) | 6.93 (6.23 to 7.65) | 8.64 (7.8 to 9.6) | 258 (234 to 286) | 0.716 (0.692 to 0.741) | <0.001 | |
| Incidence | countries / territoriesc | Cook Islands | 0 (0 to 1) | 1 (1 to 1) | 2.55 (2.09 to 3.07) | 3.57 (3 to 4.3) | 46 (34 to 61) | 1.1 (1.083 to 1.118) | <0.001 | |
| Incidence | countries / territoriesc | Costa Rica | 302 (264 to 341) | 1095 (984 to 1214) | 12.72 (11.45 to 14.19) | 20.46 (18.36 to 22.68) | 263 (229 to 302) | 1.541 (1.513 to 1.568) | <0.001 | |
| Incidence | countries / territoriesc | Croatia | 527 (460 to 596) | 793 (701 to 891) | 9.06 (7.87 to 10.37) | 14.5 (12.74 to 16.41) | 51 (36 to 65) | 1.529 (1.504 to 1.554) | <0.001 | |
| Incidence | countries / territoriesc | Cuba | 879 (776 to 1004) | 1499 (1324 to 1691) | 7.84 (6.96 to 8.83) | 10.81 (9.61 to 12.12) | 71 (55 to 88) | 1.039 (1.018 to 1.06) | <0.001 | |
| Incidence | countries / territoriesc | Cyprus | 163 (145 to 182) | 453 (407 to 506) | 19.53 (17.36 to 21.82) | 24.58 (22.04 to 27.39) | 178 (162 to 197) | 0.737 (0.669 to 0.804) | <0.001 | |
| Incidence | countries / territoriesc | Czechia | 746 (645 to 855) | 1140 (985 to 1308) | 6.63 (5.69 to 7.55) | 9.35 (8.11 to 10.67) | 53 (42 to 64) | 1.107 (1.08 to 1.134) | <0.001 | |
| Incidence | countries / territoriesc | Côte d'Ivoire | 249 (204 to 299) | 793 (665 to 935) | 3.03 (2.61 to 3.52) | 3.77 (3.27 to 4.3) | 219 (200 to 239) | 0.706 (0.686 to 0.726) | <0.001 | |
| Incidence | countries / territoriesc | Democratic People's Republic of Korea | 1825 (1608 to 2057) | 3989 (3586 to 4454) | 9.18 (8.19 to 10.33) | 12.19 (11.05 to 13.59) | 119 (105 to 135) | 0.92 (0.904 to 0.937) | <0.001 | |
| Incidence | countries / territoriesc | Democratic Republic of the Congo | 1239 (1084 to 1414) | 3669 (3201 to 4176) | 5.14 (4.6 to 5.78) | 5.94 (5.33 to 6.67) | 196 (182 to 211) | 0.464 (0.439 to 0.489) | <0.001 | |
| Incidence | countries / territoriesc | Denmark | 1211 (1099 to 1338) | 2159 (1959 to 2398) | 17.74 (16.28 to 19.45) | 23.78 (21.63 to 26.31) | 78 (68 to 90) | 0.944 (0.905 to 0.983) | <0.001 | |
| Incidence | countries / territoriesc | Djibouti | 12 (10 to 14) | 59 (51 to 68) | 4.66 (4.13 to 5.27) | 5.72 (5.06 to 6.41) | 403 (371 to 440) | 0.661 (0.636 to 0.686) | <0.001 | |
| Incidence | countries / territoriesc | Dominica | 4 (4 to 5) | 6 (6 to 7) | 6.61 (5.93 to 7.4) | 8.15 (7.31 to 9.13) | 41 (33 to 50) | 0.68 (0.659 to 0.701) | <0.001 | |
| Incidence | countries / territoriesc | Dominican Republic | 265 (231 to 306) | 695 (611 to 790) | 5.25 (4.67 to 5.88) | 6.54 (5.79 to 7.35) | 162 (146 to 180) | 0.716 (0.695 to 0.737) | <0.001 | |
| Incidence | countries / territoriesc | Ecuador | 916 (818 to 1031) | 3423 (3111 to 3786) | 12.46 (11.33 to 13.74) | 19.4 (17.68 to 21.42) | 274 (249 to 300) | 1.439 (1.397 to 1.48) | <0.001 | |
| Incidence | countries / territoriesc | Egypt | 1646 (1384 to 1951) | 5461 (4639 to 6337) | 3.23 (2.77 to 3.79) | 5.29 (4.55 to 6.1) | 232 (209 to 259) | 1.601 (1.568 to 1.634) | <0.001 | |
| Incidence | countries / territoriesc | El Salvador | 225 (194 to 261) | 530 (464 to 602) | 5.42 (4.71 to 6.16) | 8.32 (7.33 to 9.44) | 136 (120 to 156) | 1.409 (1.356 to 1.461) | <0.001 | |
| Incidence | countries / territoriesc | Equatorial Guinea | 15 (13 to 17) | 91 (79 to 106) | 5.4 (4.83 to 6.01) | 9.04 (8.08 to 10.12) | 511 (467 to 548) | 1.684 (1.634 to 1.735) | <0.001 | |
| Incidence | countries / territoriesc | Eritrea | 94 (83 to 107) | 257 (227 to 290) | 4.71 (4.27 to 5.24) | 5.55 (4.98 to 6.16) | 172 (156 to 187) | 0.531 (0.515 to 0.547) | <0.001 | |
| Incidence | countries / territoriesc | Estonia | 239 (216 to 264) | 266 (240 to 292) | 13.86 (12.44 to 15.43) | 17.72 (15.93 to 19.7) | 11 (3 to 19) | 0.777 (0.696 to 0.859) | <0.001 | |
| Incidence | countries / territoriesc | Eswatini | 52 (45 to 60) | 109 (95 to 125) | 9.55 (8.47 to 10.69) | 10.8 (9.69 to 11.98) | 108 (94 to 123) | 0.397 (0.357 to 0.437) | <0.001 | |
| Incidence | countries / territoriesc | Ethiopia | 1579 (1367 to 1830) | 3543 (3045 to 4118) | 5.14 (4.5 to 5.88) | 4.87 (4.28 to 5.55) | 124 (115 to 132) | -0.175 (-0.205 to -0.146) | <0.001 | |
| Incidence | countries / territoriesc | Fiji | 15 (12 to 18) | 24 (20 to 29) | 2.08 (1.69 to 2.5) | 2.52 (2.1 to 3.05) | 60 (50 to 71) | 0.645 (0.581 to 0.709) | <0.001 | |
| Incidence | countries / territoriesc | Finland | 1424 (1308 to 1552) | 2344 (2126 to 2583) | 22.77 (20.86 to 24.87) | 28.33 (25.67 to 31.39) | 65 (52 to 76) | 0.71 (0.684 to 0.736) | <0.001 | |
| Incidence | countries / territoriesc | France | 8101 (7288 to 8891) | 13423 (12040 to 15099) | 11.51 (10.36 to 12.78) | 13.85 (12.37 to 15.61) | 66 (56 to 78) | 0.594 (0.551 to 0.637) | <0.001 | |
| Incidence | countries / territoriesc | Gabon | 49 (44 to 55) | 149 (133 to 166) | 7.09 (6.39 to 7.86) | 9.86 (8.95 to 10.87) | 201 (184 to 219) | 1.07 (1.045 to 1.095) | <0.001 | |
| Incidence | countries / territoriesc | Gambia | 19 (16 to 23) | 65 (55 to 78) | 2.94 (2.53 to 3.43) | 3.69 (3.23 to 4.23) | 237 (218 to 259) | 0.743 (0.716 to 0.77) | <0.001 | |
| Incidence | countries / territoriesc | Georgia | 235 (200 to 280) | 189 (163 to 218) | 4.07 (3.42 to 4.84) | 4.83 (4.14 to 5.63) | -20 (-25 to -14) | 0.557 (0.509 to 0.604) | <0.001 | |
| Incidence | countries / territoriesc | Germany | 11640 (10392 to 13077) | 15883 (14213 to 17710) | 11.56 (10.25 to 12.99) | 13.4 (11.84 to 15.08) | 36 (29 to 46) | 0.47 (0.424 to 0.515) | <0.001 | |
| Incidence | countries / territoriesc | Ghana | 292 (241 to 351) | 1072 (894 to 1275) | 2.72 (2.29 to 3.21) | 3.8 (3.27 to 4.44) | 267 (244 to 292) | 1.082 (1.064 to 1.1) | <0.001 | |
| Incidence | countries / territoriesc | Greece | 1253 (1097 to 1415) | 1551 (1366 to 1744) | 10.4 (9.07 to 11.76) | 11.97 (10.46 to 13.46) | 24 (16 to 32) | 0.453 (0.437 to 0.469) | <0.001 | |
| Incidence | countries / territoriesc | Greenland | 4 (4 to 5) | 9 (8 to 10) | 8.48 (7.49 to 9.48) | 13.29 (11.97 to 14.59) | 108 (87 to 133) | 1.464 (1.419 to 1.51) | <0.001 | |
| Incidence | countries / territoriesc | Grenada | 3 (3 to 3) | 7 (6 to 8) | 3.97 (3.44 to 4.55) | 5.99 (5.27 to 6.78) | 119 (104 to 136) | 1.334 (1.299 to 1.369) | <0.001 | |
| Incidence | countries / territoriesc | Guam | 4 (3 to 5) | 6 (6 to 7) | 2.87 (2.41 to 3.4) | 3.86 (3.29 to 4.52) | 67 (52 to 85) | 0.979 (0.897 to 1.062) | <0.001 | |
| Incidence | countries / territoriesc | Guatemala | 358 (304 to 406) | 1608 (1440 to 1802) | 6.7 (5.97 to 7.45) | 11.61 (10.5 to 12.73) | 350 (320 to 383) | 1.797 (1.749 to 1.845) | <0.001 | |
| Incidence | countries / territoriesc | Guinea | 125 (106 to 147) | 316 (266 to 374) | 2.83 (2.44 to 3.26) | 3.28 (2.85 to 3.78) | 153 (140 to 169) | 0.501 (0.475 to 0.526) | <0.001 | |
| Incidence | countries / territoriesc | Guinea-Bissau | 19 (16 to 23) | 50 (41 to 60) | 2.83 (2.44 to 3.26) | 3.35 (2.91 to 3.85) | 157 (142 to 174) | 0.548 (0.517 to 0.579) | <0.001 | |
| Incidence | countries / territoriesc | Guyana | 23 (19 to 27) | 36 (31 to 41) | 3.6 (3.1 to 4.15) | 4.88 (4.26 to 5.56) | 56 (45 to 68) | 1 (0.971 to 1.029) | <0.001 | |
| Incidence | countries / territoriesc | Haiti | 224 (194 to 257) | 631 (552 to 714) | 4.84 (4.34 to 5.41) | 5.81 (5.23 to 6.43) | 182 (163 to 201) | 0.592 (0.578 to 0.606) | <0.001 | |
| Incidence | countries / territoriesc | Honduras | 419 (372 to 470) | 1828 (1660 to 2017) | 13.7 (12.51 to 15.03) | 20.92 (19.06 to 22.9) | 336 (310 to 366) | 1.383 (1.339 to 1.427) | <0.001 | |
| Incidence | countries / territoriesc | Hungary | 1188 (1066 to 1317) | 1495 (1326 to 1664) | 9.79 (8.76 to 10.85) | 12.18 (10.76 to 13.54) | 26 (17 to 35) | 0.703 (0.671 to 0.735) | <0.001 | |
| Incidence | countries / territoriesc | Iceland | 36 (32 to 41) | 69 (62 to 77) | 13.65 (11.98 to 15.41) | 15.82 (13.98 to 17.85) | 92 (78 to 104) | 0.47 (0.423 to 0.518) | <0.001 | |
| Incidence | countries / territoriesc | India | 63047 (54893 to 72108) | 198511 (174796 to 226624) | 10.61 (9.28 to 12.1) | 14.82 (13.07 to 16.89) | 215 (202 to 226) | 1.085 (1.048 to 1.122) | <0.001 | |
| Incidence | countries / territoriesc | Indonesia | 3178 (2659 to 3850) | 7807 (6661 to 9147) | 2.05 (1.75 to 2.43) | 2.69 (2.31 to 3.12) | 146 (129 to 163) | 0.869 (0.836 to 0.902) | <0.001 | |
| Incidence | countries / territoriesc | Iran (Islamic Republic of) | 1479 (1226 to 1757) | 3919 (3281 to 4569) | 3.12 (2.65 to 3.63) | 4.22 (3.6 to 4.88) | 165 (140 to 192) | 0.985 (0.954 to 1.017) | <0.001 | |
| Incidence | countries / territoriesc | Iraq | 564 (466 to 681) | 2069 (1712 to 2391) | 3.53 (2.99 to 4.14) | 5.04 (4.23 to 5.74) | 267 (232 to 303) | 1.156 (1.131 to 1.182) | <0.001 | |
| Incidence | countries / territoriesc | Ireland | 1055 (963 to 1157) | 2334 (2112 to 2589) | 28.64 (26.23 to 31.52) | 35.08 (31.79 to 38.82) | 121 (107 to 136) | 0.663 (0.621 to 0.704) | <0.001 | |
| Incidence | countries / territoriesc | Israel | 455 (398 to 518) | 1257 (1117 to 1419) | 9.49 (8.26 to 10.84) | 12.21 (10.76 to 13.93) | 176 (159 to 194) | 0.812 (0.793 to 0.831) | <0.001 | |
| Incidence | countries / territoriesc | Italy | 10880 (9361 to 12517) | 13912 (12040 to 16000) | 14.75 (12.75 to 16.93) | 14.84 (12.99 to 16.96) | 28 (22 to 34) | 0.02 (0.01 to 0.03) | <0.001 | |
| Incidence | countries / territoriesc | Jamaica | 112 (97 to 127) | 224 (198 to 252) | 5.41 (4.77 to 6.13) | 7.35 (6.51 to 8.24) | 100 (88 to 114) | 0.998 (0.968 to 1.027) | <0.001 | |
| Incidence | countries / territoriesc | Japan | 31521 (27206 to 36783) | 32060 (27599 to 37008) | 19.37 (16.8 to 22.3) | 17.03 (14.93 to 19.33) | 2 (-5 to 8) | -0.406 (-0.467 to -0.345) | <0.001 | |
| Incidence | countries / territoriesc | Jordan | 112 (91 to 136) | 673 (566 to 795) | 3.41 (2.9 to 3.97) | 5.23 (4.48 to 6.08) | 501 (448 to 568) | 1.395 (1.334 to 1.456) | <0.001 | |
| Incidence | countries / territoriesc | Kazakhstan | 596 (498 to 706) | 998 (852 to 1164) | 3.74 (3.13 to 4.42) | 5.14 (4.36 to 5.99) | 68 (56 to 81) | 1.038 (0.967 to 1.109) | <0.001 | |
| Incidence | countries / territoriesc | Kenya | 668 (573 to 786) | 2076 (1802 to 2410) | 5.15 (4.48 to 5.95) | 5.79 (5.12 to 6.62) | 211 (201 to 220) | 0.375 (0.36 to 0.39) | <0.001 | |
| Incidence | countries / territoriesc | Kiribati | 1 (1 to 2) | 3 (2 to 3) | 2.08 (1.76 to 2.46) | 2.43 (2.08 to 2.85) | 105 (95 to 118) | 0.524 (0.478 to 0.57) | <0.001 | |
| Incidence | countries / territoriesc | Kuwait | 134 (111 to 160) | 578 (483 to 678) | 7.01 (5.93 to 8.19) | 10.8 (9.2 to 12.22) | 333 (278 to 390) | 1.412 (1.313 to 1.512) | <0.001 | |
| Incidence | countries / territoriesc | Kyrgyzstan | 433 (381 to 489) | 1073 (961 to 1187) | 11.67 (10.51 to 12.94) | 17.27 (15.64 to 18.89) | 148 (131 to 167) | 1.276 (1.195 to 1.357) | <0.001 | |
| Incidence | countries / territoriesc | Lao People's Democratic Republic | 87 (75 to 102) | 277 (241 to 318) | 2.8 (2.45 to 3.2) | 4.2 (3.72 to 4.79) | 219 (197 to 244) | 1.316 (1.298 to 1.334) | <0.001 | |
| Incidence | countries / territoriesc | Latvia | 302 (275 to 333) | 273 (246 to 299) | 10.44 (9.39 to 11.6) | 13.07 (11.67 to 14.44) | -10 (-16 to -4) | 0.727 (0.679 to 0.776) | <0.001 | |
| Incidence | countries / territoriesc | Lebanon | 149 (127 to 175) | 421 (358 to 491) | 5.12 (4.38 to 5.97) | 7.12 (6.08 to 8.22) | 183 (160 to 208) | 1.075 (1.02 to 1.131) | <0.001 | |
| Incidence | countries / territoriesc | Lesotho | 90 (79 to 102) | 154 (135 to 173) | 7.89 (7.02 to 8.8) | 9.26 (8.3 to 10.19) | 71 (61 to 80) | 0.513 (0.474 to 0.552) | <0.001 | |
| Incidence | countries / territoriesc | Liberia | 54 (45 to 65) | 161 (132 to 192) | 2.99 (2.57 to 3.48) | 3.73 (3.2 to 4.26) | 200 (181 to 221) | 0.723 (0.627 to 0.818) | <0.001 | |
| Incidence | countries / territoriesc | Libya | 123 (102 to 147) | 355 (302 to 412) | 3.22 (2.75 to 3.79) | 4.6 (3.94 to 5.31) | 188 (156 to 224) | 1.145 (1.104 to 1.186) | <0.001 | |
| Incidence | countries / territoriesc | Lithuania | 490 (444 to 538) | 461 (419 to 505) | 12.6 (11.39 to 13.96) | 15.3 (13.8 to 17.03) | -6 (-12 to 2) | 0.628 (0.595 to 0.661) | <0.001 | |
| Incidence | countries / territoriesc | Luxembourg | 55 (49 to 62) | 116 (102 to 131) | 11.78 (10.46 to 13.23) | 13.8 (12.2 to 15.44) | 111 (98 to 124) | 0.51 (0.488 to 0.533) | <0.001 | |
| Incidence | countries / territoriesc | Madagascar | 301 (260 to 351) | 911 (795 to 1047) | 4.03 (3.59 to 4.58) | 4.72 (4.19 to 5.3) | 202 (186 to 219) | 0.51 (0.485 to 0.534) | <0.001 | |
| Incidence | countries / territoriesc | Malawi | 289 (252 to 334) | 738 (641 to 851) | 4.91 (4.41 to 5.54) | 5.94 (5.33 to 6.63) | 155 (144 to 168) | 0.617 (0.584 to 0.65) | <0.001 | |
| Incidence | countries / territoriesc | Malaysia | 307 (257 to 369) | 943 (807 to 1103) | 2.12 (1.79 to 2.5) | 2.85 (2.45 to 3.31) | 207 (187 to 226) | 0.959 (0.901 to 1.016) | <0.001 | |
| Incidence | countries / territoriesc | Maldives | 7 (6 to 8) | 32 (27 to 37) | 4.29 (3.8 to 4.83) | 5.7 (5.01 to 6.43) | 382 (324 to 450) | 0.915 (0.867 to 0.964) | <0.001 | |
| Incidence | countries / territoriesc | Mali | 158 (133 to 188) | 507 (419 to 602) | 2.6 (2.22 to 3.02) | 3.1 (2.66 to 3.55) | 220 (199 to 240) | 0.582 (0.559 to 0.605) | <0.001 | |
| Incidence | countries / territoriesc | Malta | 45 (40 to 51) | 78 (69 to 86) | 10.96 (9.65 to 12.34) | 12.88 (11.35 to 14.51) | 73 (61 to 87) | 0.518 (0.496 to 0.54) | <0.001 | |
| Incidence | countries / territoriesc | Marshall Islands | 1 (1 to 1) | 2 (2 to 2) | 2.64 (2.28 to 3.02) | 3.44 (2.99 to 3.9) | 110 (92 to 132) | 0.856 (0.835 to 0.877) | <0.001 | |
| Incidence | countries / territoriesc | Mauritania | 48 (41 to 56) | 151 (128 to 176) | 3.21 (2.78 to 3.69) | 4.53 (3.94 to 5.18) | 215 (198 to 234) | 1.117 (1.09 to 1.144) | <0.001 | |
| Incidence | countries / territoriesc | Mauritius | 36 (30 to 42) | 88 (76 to 102) | 3.62 (3.12 to 4.21) | 5.42 (4.72 to 6.19) | 145 (121 to 172) | 1.305 (1.286 to 1.325) | <0.001 | |
| Incidence | countries / territoriesc | Mexico | 14454 (12732 to 16243) | 34430 (30640 to 38699) | 23.52 (20.79 to 26.56) | 25.32 (22.62 to 28.44) | 138 (128 to 148) | 0.237 (0.216 to 0.259) | <0.001 | |
| Incidence | countries / territoriesc | Micronesia (Federated States of) | 2 (2 to 3) | 4 (4 to 5) | 2.9 (2.49 to 3.32) | 4.04 (3.5 to 4.58) | 69 (57 to 84) | 1.078 (1.061 to 1.096) | <0.001 | |
| Incidence | countries / territoriesc | Monaco | 3 (3 to 4) | 4 (4 to 5) | 8.13 (7.01 to 9.5) | 8.82 (7.56 to 10.21) | 34 (26 to 41) | 0.266 (0.212 to 0.32) | <0.001 | |
| Incidence | countries / territoriesc | Mongolia | 88 (75 to 103) | 240 (209 to 276) | 5.09 (4.51 to 5.74) | 7.43 (6.55 to 8.37) | 173 (145 to 202) | 1.232 (1.172 to 1.292) | <0.001 | |
| Incidence | countries / territoriesc | Montenegro | 45 (38 to 52) | 63 (55 to 72) | 6.83 (5.85 to 7.93) | 8.54 (7.35 to 9.78) | 42 (33 to 52) | 0.732 (0.697 to 0.768) | <0.001 | |
| Incidence | countries / territoriesc | Morocco | 675 (558 to 804) | 1666 (1422 to 1934) | 2.86 (2.43 to 3.37) | 4.3 (3.68 to 4.99) | 147 (127 to 170) | 1.319 (1.288 to 1.35) | <0.001 | |
| Incidence | countries / territoriesc | Mozambique | 396 (348 to 454) | 1035 (907 to 1188) | 4.64 (4.15 to 5.2) | 5.55 (4.97 to 6.18) | 161 (148 to 175) | 0.577 (0.555 to 0.599) | <0.001 | |
| Incidence | countries / territoriesc | Myanmar | 949 (821 to 1097) | 2501 (2193 to 2843) | 2.84 (2.5 to 3.2) | 4.44 (3.89 to 5.02) | 163 (143 to 186) | 1.451 (1.433 to 1.469) | <0.001 | |
| Incidence | countries / territoriesc | Namibia | 74 (64 to 85) | 195 (169 to 223) | 7.26 (6.46 to 8.1) | 9.19 (8.2 to 10.23) | 164 (148 to 180) | 0.766 (0.738 to 0.793) | <0.001 | |
| Incidence | countries / territoriesc | Nauru | 0 (0 to 0) | 0 (0 to 0) | 3.2 (2.73 to 3.68) | 4.16 (3.61 to 4.72) | 49 (40 to 59) | 0.844 (0.818 to 0.87) | <0.001 | |
| Incidence | countries / territoriesc | Nepal | 1000 (865 to 1142) | 3347 (2967 to 3847) | 7.44 (6.59 to 8.35) | 11.89 (10.61 to 13.49) | 235 (216 to 255) | 1.526 (1.493 to 1.558) | <0.001 | |
| Incidence | countries / territoriesc | Netherlands | 4323 (3888 to 4803) | 6534 (5822 to 7411) | 23.96 (21.57 to 26.7) | 24.35 (21.78 to 27.48) | 51 (41 to 63) | 0.05 (-0.023 to 0.122) | 0.179 | |
| Incidence | countries / territoriesc | New Zealand | 955 (826 to 1095) | 1721 (1493 to 1963) | 25.82 (22.36 to 29.62) | 25.05 (21.89 to 28.41) | 80 (70 to 91) | -0.09 (-0.125 to -0.056) | <0.001 | |
| Incidence | countries / territoriesc | Nicaragua | 246 (214 to 279) | 876 (785 to 977) | 10.4 (9.38 to 11.49) | 14.64 (13.33 to 16.18) | 256 (233 to 279) | 1.113 (1.086 to 1.139) | <0.001 | |
| Incidence | countries / territoriesc | Niger | 131 (109 to 158) | 461 (381 to 554) | 2.52 (2.14 to 2.93) | 2.92 (2.53 to 3.35) | 250 (231 to 273) | 0.475 (0.451 to 0.499) | <0.001 | |
| Incidence | countries / territoriesc | Nigeria | 1861 (1552 to 2253) | 5813 (4830 to 6932) | 2.7 (2.3 to 3.19) | 3.32 (2.83 to 3.84) | 212 (202 to 223) | 0.668 (0.648 to 0.688) | <0.001 | |
| Incidence | countries / territoriesc | Niue | 0 (0 to 0) | 0 (0 to 0) | 2.93 (2.52 to 3.42) | 3.99 (3.4 to 4.61) | 14 (6 to 24) | 0.997 (0.981 to 1.013) | <0.001 | |
| Incidence | countries / territoriesc | North Macedonia | 96 (79 to 114) | 173 (148 to 201) | 4.61 (3.82 to 5.45) | 6.47 (5.52 to 7.49) | 81 (67 to 97) | 1.105 (1.074 to 1.135) | <0.001 | |
| Incidence | countries / territoriesc | Northern Mariana Islands | 2 (1 to 2) | 2 (2 to 3) | 3.67 (3.13 to 4.29) | 4.26 (3.64 to 4.89) | 30 (13 to 52) | 0.485 (0.458 to 0.512) | <0.001 | |
| Incidence | countries / territoriesc | Norway | 1454 (1240 to 1710) | 1856 (1593 to 2143) | 27.81 (23.8 to 32.23) | 24.25 (21.13 to 27.68) | 28 (23 to 32) | -0.43 (-0.472 to -0.388) | <0.001 | |
| Incidence | countries / territoriesc | Oman | 42 (34 to 50) | 214 (172 to 257) | 2.41 (2.05 to 2.83) | 4.31 (3.66 to 5.04) | 412 (367 to 457) | 1.899 (1.859 to 1.939) | <0.001 | |
| Incidence | countries / territoriesc | Pakistan | 8606 (7396 to 10011) | 19454 (16729 to 22566) | 9.81 (8.62 to 11.12) | 9.36 (8.29 to 10.6) | 126 (117 to 135) | -0.1 (-0.149 to -0.051) | <0.001 | |
| Incidence | countries / territoriesc | Palau | 1 (0 to 1) | 1 (1 to 1) | 3.36 (2.88 to 3.87) | 4.32 (3.69 to 4.96) | 83 (63 to 107) | 0.805 (0.755 to 0.855) | <0.001 | |
| Incidence | countries / territoriesc | Palestine | 58 (48 to 70) | 248 (208 to 295) | 3.58 (3.02 to 4.18) | 5.14 (4.41 to 5.94) | 325 (292 to 364) | 1.18 (1.144 to 1.216) | <0.001 | |
| Incidence | countries / territoriesc | Panama | 157 (137 to 181) | 463 (413 to 520) | 7.87 (7 to 8.86) | 10.54 (9.41 to 11.83) | 195 (174 to 221) | 0.952 (0.921 to 0.982) | <0.001 | |
| Incidence | countries / territoriesc | Papua New Guinea | 71 (58 to 87) | 227 (189 to 268) | 2.03 (1.7 to 2.4) | 2.39 (2.04 to 2.77) | 219 (198 to 242) | 0.529 (0.515 to 0.543) | <0.001 | |
| Incidence | countries / territoriesc | Paraguay | 306 (261 to 360) | 1114 (986 to 1271) | 8.9 (7.78 to 10.15) | 15.15 (13.56 to 17.05) | 264 (232 to 299) | 1.727 (1.691 to 1.763) | <0.001 | |
| Incidence | countries / territoriesc | Peru | 2971 (2572 to 3358) | 9210 (8112 to 10311) | 14.82 (13.15 to 16.56) | 24.36 (21.56 to 27.12) | 210 (181 to 234) | 1.616 (1.577 to 1.655) | <0.001 | |
| Incidence | countries / territoriesc | Philippines | 2750 (2354 to 3221) | 5448 (4765 to 6291) | 5.78 (5.05 to 6.67) | 5.33 (4.71 to 6.11) | 98 (92 to 106) | -0.285 (-0.35 to -0.22) | <0.001 | |
| Incidence | countries / territoriesc | Poland | 5783 (5061 to 6623) | 6209 (5455 to 7031) | 14.18 (12.4 to 16.14) | 13.36 (11.77 to 15.08) | 7 (4 to 12) | -0.188 (-0.215 to -0.162) | <0.001 | |
| Incidence | countries / territoriesc | Portugal | 1232 (1117 to 1355) | 2182 (1950 to 2411) | 10.52 (9.41 to 11.62) | 15.03 (13.35 to 16.58) | 77 (65 to 88) | 1.153 (1.115 to 1.191) | <0.001 | |
| Incidence | countries / territoriesc | Puerto Rico | 287 (254 to 323) | 517 (461 to 591) | 7.8 (6.94 to 8.81) | 11.72 (10.32 to 13.39) | 80 (64 to 98) | 1.322 (1.3 to 1.344) | <0.001 | |
| Incidence | countries / territoriesc | Qatar | 16 (12 to 19) | 204 (159 to 248) | 3.5 (2.94 to 4.09) | 6.01 (5.03 to 7.02) | 1190 (1058 to 1319) | 1.736 (1.615 to 1.857) | <0.001 | |
| Incidence | countries / territoriesc | Republic of Korea | 4135 (3688 to 4581) | 10942 (9831 to 12139) | 9.77 (8.82 to 10.71) | 14.35 (12.97 to 15.86) | 165 (140 to 190) | 1.228 (1.159 to 1.298) | <0.001 | |
| Incidence | countries / territoriesc | Republic of Moldova | 196 (166 to 226) | 263 (229 to 306) | 4.28 (3.63 to 4.94) | 6.08 (5.26 to 7.06) | 34 (23 to 47) | 1.14 (1.114 to 1.166) | <0.001 | |
| Incidence | countries / territoriesc | Romania | 1128 (945 to 1321) | 1524 (1296 to 1769) | 4.48 (3.71 to 5.29) | 6.73 (5.71 to 7.83) | 35 (23 to 47) | 1.32 (1.284 to 1.357) | <0.001 | |
| Incidence | countries / territoriesc | Russian Federation | 12860 (11158 to 14508) | 14831 (13023 to 16750) | 7.89 (6.83 to 8.93) | 9.32 (8.18 to 10.52) | 15 (10 to 20) | 0.54 (0.525 to 0.556) | <0.001 | |
| Incidence | countries / territoriesc | Rwanda | 216 (188 to 248) | 622 (550 to 707) | 5.03 (4.53 to 5.59) | 6.46 (5.77 to 7.17) | 189 (172 to 206) | 0.813 (0.746 to 0.879) | <0.001 | |
| Incidence | countries / territoriesc | Saint Kitts and Nevis | 3 (2 to 3) | 7 (6 to 7) | 7.28 (6.54 to 8.06) | 10.16 (9.18 to 11.27) | 141 (123 to 163) | 1.09 (1.053 to 1.126) | <0.001 | |
| Incidence | countries / territoriesc | Saint Lucia | 8 (7 to 9) | 20 (18 to 22) | 7.15 (6.43 to 7.9) | 9.46 (8.53 to 10.37) | 163 (141 to 184) | 0.902 (0.865 to 0.939) | <0.001 | |
| Incidence | countries / territoriesc | Saint Vincent and the Grenadines | 4 (3 to 5) | 7 (6 to 8) | 4.37 (3.81 to 5) | 5.56 (4.87 to 6.37) | 77 (62 to 92) | 0.783 (0.758 to 0.808) | <0.001 | |
| Incidence | countries / territoriesc | Samoa | 4 (4 to 5) | 7 (6 to 9) | 3.07 (2.64 to 3.6) | 3.87 (3.33 to 4.42) | 70 (58 to 83) | 0.758 (0.684 to 0.832) | <0.001 | |
| Incidence | countries / territoriesc | San Marino | 2 (2 to 3) | 3 (3 to 4) | 7.89 (6.77 to 9.25) | 8.39 (7.11 to 9.72) | 58 (48 to 68) | 0.204 (0.169 to 0.238) | <0.001 | |
| Incidence | countries / territoriesc | Sao Tome and Principe | 3 (2 to 3) | 8 (6 to 9) | 3.19 (2.73 to 3.68) | 4.16 (3.58 to 4.75) | 174 (155 to 196) | 0.867 (0.845 to 0.888) | <0.001 | |
| Incidence | countries / territoriesc | Saudi Arabia | 398 (327 to 478) | 2035 (1662 to 2429) | 2.74 (2.33 to 3.23) | 4.68 (3.95 to 5.47) | 412 (361 to 471) | 1.736 (1.691 to 1.782) | <0.001 | |
| Incidence | countries / territoriesc | Senegal | 157 (132 to 187) | 455 (382 to 541) | 3.04 (2.6 to 3.5) | 3.73 (3.2 to 4.28) | 190 (176 to 207) | 0.679 (0.659 to 0.698) | <0.001 | |
| Incidence | countries / territoriesc | Serbia | 680 (616 to 752) | 1005 (888 to 1136) | 6.03 (5.48 to 6.64) | 8.98 (7.93 to 10.22) | 48 (36 to 59) | 1.293 (1.271 to 1.316) | <0.001 | |
| Incidence | countries / territoriesc | Seychelles | 2 (1 to 2) | 4 (3 to 5) | 2.55 (2.16 to 3) | 3.39 (2.9 to 3.94) | 135 (112 to 159) | 0.922 (0.89 to 0.954) | <0.001 | |
| Incidence | countries / territoriesc | Sierra Leone | 86 (72 to 103) | 221 (184 to 266) | 2.83 (2.41 to 3.28) | 3.28 (2.85 to 3.77) | 156 (141 to 170) | 0.473 (0.444 to 0.502) | <0.001 | |
| Incidence | countries / territoriesc | Singapore | 196 (167 to 229) | 614 (523 to 714) | 6.18 (5.36 to 7.09) | 8.25 (7.1 to 9.53) | 213 (186 to 244) | 0.938 (0.893 to 0.984) | <0.001 | |
| Incidence | countries / territoriesc | Slovakia | 281 (241 to 324) | 465 (406 to 531) | 5.05 (4.32 to 5.84) | 7.07 (6.13 to 8.05) | 66 (54 to 79) | 1.087 (1.049 to 1.125) | <0.001 | |
| Incidence | countries / territoriesc | Slovenia | 277 (249 to 309) | 495 (441 to 545) | 12.01 (10.72 to 13.44) | 17.37 (15.4 to 19.44) | 78 (64 to 92) | 1.204 (1.171 to 1.237) | <0.001 | |
| Incidence | countries / territoriesc | Solomon Islands | 7 (6 to 8) | 21 (18 to 25) | 2.59 (2.24 to 2.98) | 3.41 (2.96 to 3.89) | 203 (183 to 226) | 0.892 (0.855 to 0.93) | <0.001 | |
| Incidence | countries / territoriesc | Somalia | 231 (200 to 266) | 624 (541 to 720) | 5.02 (4.51 to 5.57) | 5.14 (4.64 to 5.66) | 170 (156 to 184) | 0.078 (0.07 to 0.086) | <0.001 | |
| Incidence | countries / territoriesc | South Africa | 5847 (5087 to 6617) | 9168 (8067 to 10269) | 17.17 (15.2 to 19.27) | 15.26 (13.52 to 17.11) | 57 (50 to 64) | -0.379 (-0.398 to -0.361) | <0.001 | |
| Incidence | countries / territoriesc | South Sudan | 162 (139 to 188) | 322 (277 to 373) | 4.34 (3.84 to 4.89) | 5 (4.45 to 5.61) | 100 (87 to 113) | 0.465 (0.434 to 0.496) | <0.001 | |
| Incidence | countries / territoriesc | Spain | 5347 (4937 to 5790) | 9381 (8795 to 10037) | 11.67 (10.8 to 12.56) | 14.01 (13.16 to 14.91) | 75 (65 to 86) | 0.589 (0.576 to 0.602) | <0.001 | |
| Incidence | countries / territoriesc | Sri Lanka | 350 (292 to 423) | 748 (642 to 881) | 2.23 (1.89 to 2.64) | 3.04 (2.59 to 3.54) | 113 (96 to 134) | 1.009 (0.947 to 1.072) | <0.001 | |
| Incidence | countries / territoriesc | Sudan | 425 (351 to 506) | 1539 (1283 to 1820) | 2.47 (2.08 to 2.88) | 3.73 (3.19 to 4.32) | 262 (234 to 292) | 1.341 (1.31 to 1.373) | <0.001 | |
| Incidence | countries / territoriesc | Suriname | 13 (11 to 15) | 29 (25 to 33) | 3.84 (3.33 to 4.41) | 4.78 (4.15 to 5.51) | 126 (110 to 143) | 0.721 (0.694 to 0.748) | <0.001 | |
| Incidence | countries / territoriesc | Sweden | 2716 (2388 to 3098) | 3213 (2787 to 3649) | 23.21 (20.48 to 26.29) | 20.8 (18.45 to 23.46) | 18 (13 to 23) | -0.357 (-0.389 to -0.324) | <0.001 | |
| Incidence | countries / territoriesc | Switzerland | 1542 (1375 to 1730) | 2528 (2244 to 2832) | 17.49 (15.6 to 19.53) | 18.98 (16.84 to 21.32) | 64 (54 to 75) | 0.263 (0.248 to 0.278) | <0.001 | |
| Incidence | countries / territoriesc | Syrian Arab Republic | 344 (285 to 415) | 740 (621 to 875) | 3.22 (2.71 to 3.79) | 5.21 (4.41 to 6.17) | 115 (90 to 143) | 1.573 (1.524 to 1.623) | <0.001 | |
| Incidence | countries / territoriesc | Taiwan (Province of China) | 1948 (1717 to 2182) | 3740 (3503 to 3981) | 10.02 (8.89 to 11.17) | 10.47 (9.94 to 11.03) | 92 (71 to 116) | 0.175 (0.088 to 0.262) | <0.001 | |
| Incidence | countries / territoriesc | Tajikistan | 254 (218 to 297) | 708 (619 to 809) | 6.07 (5.33 to 6.84) | 7.96 (7.14 to 8.93) | 178 (159 to 202) | 0.881 (0.822 to 0.94) | <0.001 | |
| Incidence | countries / territoriesc | Thailand | 1975 (1687 to 2267) | 4858 (4188 to 5575) | 3.8 (3.3 to 4.34) | 5.54 (4.79 to 6.32) | 146 (124 to 174) | 1.233 (1.172 to 1.295) | <0.001 | |
| Incidence | countries / territoriesc | Timor-Leste | 15 (13 to 18) | 43 (37 to 49) | 2.67 (2.34 to 3.07) | 3.9 (3.46 to 4.45) | 187 (167 to 211) | 1.217 (1.181 to 1.254) | <0.001 | |
| Incidence | countries / territoriesc | Togo | 70 (58 to 84) | 236 (198 to 277) | 2.96 (2.55 to 3.43) | 3.59 (3.09 to 4.13) | 239 (216 to 261) | 0.625 (0.593 to 0.657) | <0.001 | |
| Incidence | countries / territoriesc | Tokelau | 0 (0 to 0) | 0 (0 to 0) | 2.6 (2.24 to 3.01) | 3.61 (3.11 to 4.15) | 36 (28 to 44) | 1.07 (1.044 to 1.095) | <0.001 | |
| Incidence | countries / territoriesc | Tonga | 2 (2 to 3) | 4 (3 to 4) | 2.89 (2.47 to 3.37) | 3.69 (3.15 to 4.28) | 48 (39 to 58) | 0.797 (0.76 to 0.834) | <0.001 | |
| Incidence | countries / territoriesc | Trinidad and Tobago | 97 (86 to 109) | 201 (184 to 221) | 9.36 (8.44 to 10.38) | 12.17 (11.1 to 13.4) | 107 (92 to 125) | 0.853 (0.835 to 0.87) | <0.001 | |
| Incidence | countries / territoriesc | Tunisia | 247 (206 to 293) | 588 (503 to 684) | 3.14 (2.64 to 3.69) | 4.7 (4 to 5.47) | 138 (114 to 166) | 1.321 (1.286 to 1.356) | <0.001 | |
| Incidence | countries / territoriesc | Turkmenistan | 104 (85 to 124) | 224 (193 to 262) | 3.26 (2.72 to 3.84) | 4.31 (3.71 to 5) | 116 (101 to 133) | 0.919 (0.895 to 0.943) | <0.001 | |
| Incidence | countries / territoriesc | Tuvalu | 0 (0 to 0) | 0 (0 to 0) | 2.53 (2.16 to 2.91) | 3.38 (2.92 to 3.87) | 89 (80 to 100) | 0.943 (0.912 to 0.973) | <0.001 | |
| Incidence | countries / territoriesc | Türkiye | 3572 (3172 to 4045) | 10101 (9023 to 11251) | 6.77 (6.06 to 7.61) | 10.88 (9.76 to 12.08) | 183 (160 to 211) | 1.544 (1.501 to 1.586) | <0.001 | |
| Incidence | countries / territoriesc | Uganda | 455 (391 to 528) | 1465 (1265 to 1689) | 4.66 (4.14 to 5.29) | 5.77 (5.16 to 6.52) | 222 (207 to 239) | 0.7 (0.667 to 0.733) | <0.001 | |
| Incidence | countries / territoriesc | Ukraine | 2073 (1736 to 2451) | 2321 (1998 to 2711) | 3.63 (3.03 to 4.29) | 4.6 (3.93 to 5.31) | 12 (4 to 21) | 0.763 (0.728 to 0.798) | <0.001 | |
| Incidence | countries / territoriesc | United Arab Emirates | 65 (53 to 78) | 595 (475 to 742) | 3.45 (2.93 to 4) | 5.63 (4.8 to 6.6) | 811 (643 to 987) | 1.6 (1.569 to 1.63) | <0.001 | |
| Incidence | countries / territoriesc | United Kingdom | 18074 (16019 to 20333) | 25538 (22734 to 28825) | 25.25 (22.57 to 28.19) | 27.37 (24.58 to 30.42) | 41 (38 to 44) | 0.264 (0.243 to 0.286) | <0.001 | |
| Incidence | countries / territoriesc | United Republic of Tanzania | 774 (676 to 893) | 2354 (2048 to 2703) | 4.94 (4.39 to 5.57) | 5.99 (5.35 to 6.74) | 204 (187 to 220) | 0.627 (0.605 to 0.649) | <0.001 | |
| Incidence | countries / territoriesc | United States Virgin Islands | 6 (5 to 7) | 9 (8 to 10) | 5.84 (5.09 to 6.63) | 7.45 (6.55 to 8.49) | 58 (41 to 74) | 0.784 (0.765 to 0.804) | <0.001 | |
| Incidence | countries / territoriesc | United States of America | 43582 (39473 to 48167) | 81505 (73805 to 90798) | 15.52 (14.08 to 17.13) | 18.27 (16.75 to 20.05) | 87 (81 to 93) | 0.532 (0.489 to 0.575) | <0.001 | |
| Incidence | countries / territoriesc | Uruguay | 328 (297 to 366) | 542 (490 to 604) | 9.46 (8.49 to 10.53) | 12.75 (11.43 to 14.2) | 65 (56 to 74) | 0.98 (0.941 to 1.019) | <0.001 | |
| Incidence | countries / territoriesc | Uzbekistan | 2012 (1727 to 2304) | 5043 (4457 to 5634) | 11.4 (10.13 to 12.74) | 14.03 (12.48 to 15.6) | 151 (126 to 179) | 0.67 (0.61 to 0.731) | <0.001 | |
| Incidence | countries / territoriesc | Vanuatu | 3 (3 to 4) | 9 (7 to 10) | 2.48 (2.13 to 2.87) | 3.1 (2.68 to 3.53) | 187 (172 to 208) | 0.711 (0.688 to 0.733) | <0.001 | |
| Incidence | countries / territoriesc | Venezuela (Bolivarian Republic of) | 1852 (1628 to 2068) | 5297 (4796 to 5805) | 12.82 (11.61 to 14.1) | 17.99 (16.27 to 19.73) | 186 (161 to 214) | 1.082 (1.011 to 1.154) | <0.001 | |
| Incidence | countries / territoriesc | Viet Nam | 2222 (1914 to 2572) | 7667 (6708 to 8792) | 4.13 (3.58 to 4.72) | 6.98 (6.12 to 7.93) | 245 (213 to 281) | 1.714 (1.696 to 1.732) | <0.001 | |
| Incidence | countries / territoriesc | Yemen | 240 (197 to 287) | 901 (749 to 1056) | 2.3 (1.94 to 2.68) | 2.97 (2.56 to 3.43) | 275 (247 to 306) | 0.844 (0.821 to 0.867) | <0.001 | |
| Incidence | countries / territoriesc | Zambia | 219 (191 to 252) | 765 (661 to 878) | 4.53 (4.04 to 5) | 5.79 (5.18 to 6.45) | 249 (227 to 272) | 0.804 (0.783 to 0.825) | <0.001 | |
| Incidence | countries / territoriesc | Zimbabwe | 408 (345 to 476) | 714 (608 to 822) | 5.46 (4.73 to 6.12) | 5.55 (4.91 to 6.25) | 75 (64 to 86) | 0.046 (-0.031 to 0.124) | 0.238 |