prior knowledge of Biomarkers
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snpId
rs1805010
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pubmedId
24782180
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geneId
3565
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geneSymbol
IL4
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diseaseId
umls:C0003873
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sourceId
BeFree
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sentence
The data indicate that the rs1805010 minor allele contributes to increased Th17 cell frequency, enhanced clinical activity, and accelerated radiographic progression in RA by rendering CD4 T cells from RA patients insensitive to the attenuating effect of IL-4 on Th17 cell development.
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score
0.033418483
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Year
2013
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geneSymbol_dbSNP
IL4R
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CHROMOSOME
16
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POS
27344882
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REF
A
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ALT
C,G,T
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