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prior knowledge of Biomarkers

  • snpId
    rs2228145
  • pubmedId
    23593036
  • geneId
    3570
  • geneSymbol
    IL6R
  • diseaseId
    umls:C0003873
  • sourceId
    BeFree
  • sentence
    Although a common, non-synonymous variant in the IL-6 receptor gene (IL6R Asp358Ala; rs2228145 A>C) is associated with the risk of several common diseases, with the 358Ala allele conferring protection from coronary heart disease (CHD), rheumatoid arthritis (RA), atrial fibrillation (AF), abdominal aortic aneurysm (AAA), and increased susceptibility to asthma, the variant's effect on IL-6 signaling is not known.
  • score
    0.247719925
  • Year
    2013
  • geneSymbol_dbSNP
    IL6R
  • CHROMOSOME
    1
  • POS
    154454494
  • REF
    A
  • ALT
    C,T
  • download source file
    PedAM.xlsx