RABC

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Biomarkers name	Biomarker Type	Source database	Information	Details
RASGRP1	gene	CTD	Gene Symbol=RASGRP1; Gene ID=10125; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=marker/mechanism; Inference Network=Acetaminophen\|Antirheumatic Agents\|Cyclosporine\|Dexamethasone\|glyphosate\|Hydroxychloroquine\|Indomethacin\|Methotrexate\|ochratoxin A\|Oxygen\|Resveratrol\|Sulfasalazine\|Tobacco Smoke Pollution\|Tretinoin; Inference Score=39.84; Reference Count=172	details
MMP10	gene	CTD	Gene Symbol=MMP10; Gene ID=4319; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=marker/mechanism; Inference Network=Acetaminophen\|Azathioprine\|chloroquine diphosphate\|Curcumin\|Cyclosporine\|Gold Sodium Thiomalate\|Indomethacin\|Methotrexate\|Methylprednisolone\|Oxygen\|Piroxicam\|Plant Extracts\|Prednisolone\|Tobacco Smoke Pollution\|Tretinoin; Inference Score=38.42; Reference Count=183	details
BMP4	gene	CTD	Gene Symbol=BMP4; Gene ID=652; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=marker/mechanism; Inference Network=Acetaminophen\|Air Pollutants\|Betamethasone\|Cyclosporine\|Dexamethasone\|Diclofenac\|Freund's Adjuvant\|Maneb\|Methotrexate\|ochratoxin A\|Oxygen\|Ozone\|Resveratrol\|Tobacco Smoke Pollution\|Tretinoin\|Vorinostat; Inference Score=38.02; Reference Count=144	details
ANXA3	gene	CTD	Gene Symbol=ANXA3; Gene ID=306; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=marker/mechanism; Inference Network=Acetaminophen\|Air Pollutants\|Arsenic Trioxide\|Cyclosporine\|Dexamethasone\|Flurbiprofen\|Freund's Adjuvant\|Indomethacin\|Leflunomide\|ochratoxin A\|Oxygen\|Ozone\|Resveratrol\|Tobacco Smoke Pollution\|Tretinoin\|Vorinostat; Inference Score=37.94; Reference Count=49	details
HSD11B1	gene	CTD	Gene Symbol=HSD11B1; Gene ID=3290; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=marker/mechanism; Inference Network=Acetaminophen\|Air Pollutants\|Azathioprine\|Cyclosporine\|Dexamethasone\|Dinoprostone\|Glucocorticoids\|Gold Sodium Thiomalate\|Hydrocortisone\|Indomethacin\|Meloxicam\|Methotrexate\|Methylprednisolone\|Piroxicam\|Prednisolone\|Resveratrol\|Tobacco Smoke Pollution; Inference Score=37.75; Reference Count=181	details
RUNX2	gene	CTD	Gene Symbol=RUNX2; Gene ID=860; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=marker/mechanism; Inference Network=Acetaminophen\|Air Pollutants\|Arsenic Trioxide\|Chloroquine\|Curcumin\|Dexamethasone\|Diclofenac\|Dinoprostone\|Enalapril\|Methotrexate\|ochratoxin A\|Oxygen\|Plant Extracts\|Resveratrol\|Tacrolimus\|tamibarotene\|Tobacco Smoke Pollution\|Tretinoin; Inference Score=37.55; Reference Count=165	details
REL	gene	CTD	Gene Symbol=REL; Gene ID=5966; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=marker/mechanism; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Curcumin\|deoxynivalenol\|Dexamethasone\|Freund's Adjuvant\|Oxygen\|Pesticides\|Plant Extracts\|Resveratrol\|Tacrolimus\|Tretinoin; Inference Score=37.3; Reference Count=31	details
NR4A3	gene	CTD	Gene Symbol=NR4A3; Gene ID=8013; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=marker/mechanism; Inference Network=Air Pollutants\|Aspirin\|Azathioprine\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Gold Sodium Thiomalate\|Leflunomide\|Methotrexate\|Methylprednisolone\|Ozone\|Piroxicam\|Prednisolone\|Tobacco Smoke Pollution\|Tretinoin; Inference Score=37.12; Reference Count=186	details
PON1	gene	CTD	Gene Symbol=PON1; Gene ID=5444; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=marker/mechanism; Inference Network=Acetaminophen\|Air Pollutants\|Aspirin\|Cyclophosphamide\|Cyclosporine\|Dexamethasone\|Diclofenac\|entinostat\|Mefenamic Acid\|Methotrexate\|ochratoxin A\|Oxygen\|Ozone\|Pesticides\|Reactive Oxygen Species\|Resveratrol\|Salicylates\|Tobacco Smoke Pollution\|Vorinostat; Inference Score=36.85; Reference Count=160	details
IL6ST	gene	CTD	Gene Symbol=IL6ST; Gene ID=3572; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=marker/mechanism; Inference Network=Acetaminophen\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Auranofin\|Cyclosporine\|Dexamethasone\|Indomethacin\|Leflunomide\|Oxygen\|Ozone\|Resveratrol\|Thalidomide\|Tobacco Smoke Pollution\|Tretinoin; Inference Score=36.84; Reference Count=71	details
TLE3	gene	CTD	Gene Symbol=TLE3; Gene ID=7090; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=marker/mechanism; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Cyclosporine\|Dexamethasone\|Indomethacin\|Leflunomide\|Ozone\|Plant Extracts\|Tobacco Smoke Pollution\|Tretinoin\|valdecoxib; Inference Score=36.52; Reference Count=46	details
NDUFA4L2	gene	CTD	Gene Symbol=NDUFA4L2; Gene ID=56901; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=marker/mechanism; Inference Network=Azathioprine\|chloroquine diphosphate\|Dexamethasone\|Gold Sodium Thiomalate\|Methotrexate\|Methylprednisolone\|Oxygen\|Piroxicam\|Plant Extracts\|Prednisolone; Inference Score=36.38; Reference Count=163	details
TMPO	gene	CTD	Gene Symbol=TMPO; Gene ID=7112; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=marker/mechanism; Inference Network=Acetaminophen\|Arsenic Trioxide\|Azathioprine\|Cyclosporine\|deoxynivalenol\|Leflunomide\|Piroxicam\|Plant Extracts\|Resveratrol\|tamibarotene\|Thalidomide\|Tobacco Smoke Pollution\|Tretinoin\|Vorinostat; Inference Score=35.98; Reference Count=43	details
STS	gene	CTD	Gene Symbol=STS; Gene ID=412; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=marker/mechanism; Inference Network=Acetaminophen\|Air Pollutants\|Azathioprine\|Curcumin\|Cyclosporine\|Diclofenac\|Gold Sodium Thiomalate\|Leflunomide\|Methotrexate\|Methylprednisolone\|Pesticides\|Piroxicam\|Prednisolone\|Tretinoin\|triptolide; Inference Score=35.51; Reference Count=180	details
FOXP3	gene	CTD	Gene Symbol=FOXP3; Gene ID=50943; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=marker/mechanism; Inference Network=Air Pollutants\|Arsenic Trioxide\|Cyclophosphamide\|deoxynivalenol\|Freund's Adjuvant\|Leflunomide\|Levamisole\|Ozone\|Plant Extracts\|Quinacrine\|Resveratrol\|tamibarotene\|triptolide; Inference Score=35.46; Reference Count=36	details
SMS	gene	CTD	Gene Symbol=SMS; Gene ID=6611; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=marker/mechanism; Inference Network=Acetaminophen\|Arsenic Trioxide\|Azathioprine\|Dexamethasone\|Gold Sodium Thiomalate\|Indomethacin\|Methotrexate\|Methylprednisolone\|Piroxicam\|Prednisolone\|Tobacco Smoke Pollution; Inference Score=34.8; Reference Count=175	details
GSDME	gene	CTD	Gene Symbol=GSDME; Gene ID=1687; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=marker/mechanism; Inference Network=Acetaminophen\|Azathioprine\|chloroquine diphosphate\|Cyclosporine\|Dexamethasone\|entinostat\|Gold Sodium Thiomalate\|Methotrexate\|Methylprednisolone\|Piroxicam\|Prednisolone\|Tobacco Smoke Pollution; Inference Score=34.79; Reference Count=166	details
CRP	gene	CTD	Gene Symbol=CRP; Gene ID=1401; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=marker/mechanism; Inference Network=Acetaminophen\|Air Pollutants\|alclofenac\|Arsenic Trioxide\|Curcumin\|Cyclosporine\|deoxynivalenol\|Diclofenac\|Freund's Adjuvant\|Penicillamine\|Plant Extracts\|Reactive Oxygen Species\|Resveratrol\|rifamycin SV\|Thalidomide\|Tobacco Smoke Pollution\|triptolide; Inference Score=33.84; Reference Count=205	details
ABCC2	gene	CTD	Gene Symbol=ABCC2; Gene ID=1244; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=marker/mechanism; Inference Network=Acetaminophen\|Air Pollutants\|Arsenic Trioxide\|Azathioprine\|Chlorambucil\|Chloroquine\|Curcumin\|Cyclosporine\|Dexamethasone\|Diclofenac\|Indomethacin\|Methotrexate\|ochratoxin A\|Oxygen\|Plant Extracts\|Reactive Oxygen Species\|Resveratrol\|Sulfasalazine\|Tobacco Smoke Pollution\|Tretinoin\|valdecoxib; Inference Score=33.75; Reference Count=207	details
GATA3	gene	CTD	Gene Symbol=GATA3; Gene ID=2625; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=marker/mechanism; Inference Network=Acetaminophen\|Arsenic Trioxide\|Cyclophosphamide\|Dexamethasone\|entinostat\|Levamisole\|Methotrexate\|Ozone\|Plant Extracts\|Resveratrol\|Thalidomide\|Tobacco Smoke Pollution\|Tretinoin\|Vorinostat; Inference Score=32.75; Reference Count=141	details