RABC

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Biomarkers name	Biomarker Type	Source database	Information	Details
TEK	gene	CTD	Gene Symbol=TEK; Gene ID=7010; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Antirheumatic Agents\|Arsenic Trioxide\|Dexamethasone\|Enalapril\|Indomethacin\|mancozeb\|Maneb\|Methotrexate\|Naproxen\|Ozone\|Plant Extracts\|Sulindac\|Thalidomide\|Tobacco Smoke Pollution; Inference Score=42.23; Reference Count=152	details
RORC	gene	CTD	Gene Symbol=RORC; Gene ID=6097; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Cyclophosphamide\|Cyclosporine\|Dexamethasone\|Diclofenac\|Dinoprostone\|Freund's Adjuvant\|Leflunomide\|Levamisole\|Ozone\|thymoquinone\|Tobacco Smoke Pollution\|tofacitinib\|triptolide\|valdecoxib\|Vorinostat; Inference Score=42.17; Reference Count=54	details
ZEB1	gene	CTD	Gene Symbol=ZEB1; Gene ID=6935; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|entinostat\|Indomethacin\|Leflunomide\|Methotrexate\|Oxygen\|Ozone\|Resveratrol\|Tretinoin; Inference Score=42.17; Reference Count=162	details
PLK4	gene	CTD	Gene Symbol=PLK4; Gene ID=10733; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Antirheumatic Agents\|Arsenic Trioxide\|Curcumin\|Cyclosporine\|Dexamethasone\|Methotrexate\|Oxygen\|Ozone\|Piroxicam\|Plant Extracts\|Resveratrol\|tamibarotene\|Tretinoin\|Vorinostat; Inference Score=42.1; Reference Count=134	details
CXCL12	gene	CTD	Gene Symbol=CXCL12; Gene ID=6387; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Arsenic Trioxide\|Chloroquine\|Curcumin\|Cyclophosphamide\|Cyclosporine\|Dexamethasone\|Edaravone\|entinostat\|Freund's Adjuvant\|glyphosate\|Indomethacin\|Leflunomide\|Methotrexate\|Oxygen\|Plant Extracts\|Resveratrol\|Tobacco Smoke Pollution\|Tretinoin\|Vorinostat; Inference Score=42.09; Reference Count=185	details
DDX58	gene	CTD	Gene Symbol=DDX58; Gene ID=23586; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Azathioprine\|chloroquine diphosphate\|Cyclosporine\|Diclofenac\|Gold Sodium Thiomalate\|Hydroxychloroquine\|Methotrexate\|Methylprednisolone\|Ozone\|Piroxicam\|Plant Extracts\|Prednisolone\|Tobacco Smoke Pollution\|Tretinoin; Inference Score=41.96; Reference Count=181	details
IKBKG	gene	CTD	Gene Symbol=IKBKG; Gene ID=8517; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Chloroquine\|Curcumin\|Diclofenac\|Indomethacin\|Methotrexate\|Oxygen\|Ozone\|Plant Extracts\|Resveratrol\|Tobacco Smoke Pollution\|Vorinostat; Inference Score=41.96; Reference Count=173	details
GCLM	gene	CTD	Gene Symbol=GCLM; Gene ID=2730; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Azathioprine\|Chlorambucil\|Curcumin\|Cyclosporine\|Dexamethasone\|Diclofenac\|entinostat\|glyphosate\|Indomethacin\|Ketoprofen\|Naproxen\|ochratoxin A\|Oxygen\|Ozone\|Reactive Oxygen Species\|Resveratrol\|Tobacco Smoke Pollution\|Tretinoin\|valdecoxib; Inference Score=41.95; Reference Count=78	details
NRG1	gene	CTD	Gene Symbol=NRG1; Gene ID=3084; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Arsenic Trioxide\|Cyclophosphamide\|Cyclosporine\|Dexamethasone\|Dinoprostone\|entinostat\|Indomethacin\|Maneb\|Methotrexate\|ochratoxin A\|Oxygen\|Ozone\|Resveratrol\|Tobacco Smoke Pollution\|Tretinoin\|Vorinostat; Inference Score=41.87; Reference Count=153	details
IFI27	gene	CTD	Gene Symbol=IFI27; Gene ID=3429; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Azathioprine\|Dexamethasone\|Diclofenac\|Gold Sodium Thiomalate\|Indomethacin\|Methotrexate\|Methylprednisolone\|Ozone\|Piroxicam\|Plant Extracts\|Prednisolone\|Sulindac\|Tobacco Smoke Pollution\|tofacitinib; Inference Score=41.83; Reference Count=195	details
OPA1	gene	CTD	Gene Symbol=OPA1; Gene ID=4976; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Curcumin\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|Oxygen\|Ozone\|Piroxicam\|Plant Extracts\|Resveratrol\|Tobacco Smoke Pollution; Inference Score=41.83; Reference Count=35	details
CCNG1	gene	CTD	Gene Symbol=CCNG1; Gene ID=900; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|deoxynivalenol\|Dexamethasone\|Diclofenac\|Freund's Adjuvant\|glyphosate\|Indomethacin\|Methotrexate\|ochratoxin A\|Oxygen\|Ozone\|Resveratrol\|Sulfasalazine\|tamibarotene\|Tretinoin; Inference Score=41.79; Reference Count=175	details
PTGES	gene	CTD	Gene Symbol=PTGES; Gene ID=9536; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Arsenic Trioxide\|Aspirin\|Curcumin\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|Dinoprostone\|entinostat\|Gold Sodium Thiomalate\|Indomethacin\|mancozeb\|Meloxicam\|Oxygen\|Resveratrol\|Tretinoin; Inference Score=41.72; Reference Count=70	details
F3	gene	CTD	Gene Symbol=F3; Gene ID=2152; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Arsenic Trioxide\|chloroquine diphosphate\|Curcumin\|Cyclophosphamide\|deoxynivalenol\|Dexamethasone\|Enalapril\|Indomethacin\|mancozeb\|Methotrexate\|ochratoxin A\|Oxygen\|Ozone\|Resveratrol\|Sulfasalazine\|tamibarotene\|Tobacco Smoke Pollution\|Tretinoin; Inference Score=41.7; Reference Count=175	details
IRS1	gene	CTD	Gene Symbol=IRS1; Gene ID=3667; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Azathioprine\|Curcumin\|Cyclophosphamide\|Cyclosporine\|Dexamethasone\|Diclofenac\|glyphosate\|Leflunomide\|Oxygen\|Pesticides\|Plant Extracts\|Resveratrol\|Tobacco Smoke Pollution\|Tretinoin\|triptolide; Inference Score=41.68; Reference Count=73	details
MR1	gene	CTD	Gene Symbol=MR1; Gene ID=3140; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Angiotensin-Converting Enzyme Inhibitors\|Antirheumatic Agents\|Arsenic Trioxide\|Cyclophosphamide\|Cyclosporine\|Diclofenac\|Mefenamic Acid\|Minocycline\|Ozone\|Piroxicam\|Resveratrol\|Sulfasalazine; Inference Score=41.64; Reference Count=66	details
CDK2	gene	CTD	Gene Symbol=CDK2; Gene ID=1017; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Curcumin\|Cyclophosphamide\|Cyclosporine\|Dexamethasone\|Diclofenac\|glyphosate\|GW 506033X\|Indomethacin\|Maneb\|Methotrexate\|ochratoxin A\|Piroxicam\|Plant Extracts\|Resveratrol\|Sulindac\|thymoquinone\|Tretinoin\|triptolide; Inference Score=41.61; Reference Count=177	details
MT1X	gene	CTD	Gene Symbol=MT1X; Gene ID=4501; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Antirheumatic Agents\|Arsenic Trioxide\|Cyclosporine\|Dexamethasone\|entinostat\|Gold\|Hydrocortisone\|Leflunomide\|Oxygen\|Penicillamine\|Piroxicam\|Resveratrol\|Tobacco Smoke Pollution\|Tretinoin\|Vorinostat; Inference Score=41.61; Reference Count=211	details
MTHFD2	gene	CTD	Gene Symbol=MTHFD2; Gene ID=10797; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Antirheumatic Agents\|Arsenic Trioxide\|Cyclophosphamide\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|entinostat\|Leflunomide\|Oxygen\|Ozone\|Resveratrol\|Sulindac\|Tobacco Smoke Pollution\|Tretinoin; Inference Score=41.61; Reference Count=52	details
UPP1	gene	CTD	Gene Symbol=UPP1; Gene ID=7378; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Azathioprine\|Cyclosporine\|Dexamethasone\|Indomethacin\|Methotrexate\|Oxygen\|Plant Extracts\|Resveratrol\|Thalidomide\|Tobacco Smoke Pollution\|Tretinoin\|triptolide; Inference Score=41.61; Reference Count=159	details