RABC

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Biomarkers name	Biomarker Type	Source database	Information	Details
SLC22A2	gene	CTD	Gene Symbol=SLC22A2; Gene ID=6582; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Aspirin\|Auranofin\|Chloroquine\|Cyclosporine\|Dexamethasone\|Famotidine\|Hydrocortisone\|Indomethacin\|Maneb\|Naproxen\|ochratoxin A\|Oxygen\|Ozone\|Piroxicam\|Plant Extracts\|Prednisone\|Sulindac\|Thalidomide\|Tobacco Smoke Pollution\|Tretinoin\|valdecoxib; Inference Score=42.78; Reference Count=97	details
MAP2K1	gene	CTD	Gene Symbol=MAP2K1; Gene ID=5604; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Air Pollutants\|Arsenic Trioxide\|Aspirin\|Azathioprine\|Curcumin\|Cyclosporine\|Dexamethasone\|glyphosate\|Gold\|Indomethacin\|Maneb\|ochratoxin A\|Oxygen\|Ozone\|Plant Extracts\|Reactive Oxygen Species\|Resveratrol\|Tobacco Smoke Pollution\|Tretinoin\|Vorinostat; Inference Score=42.75; Reference Count=77	details
SPTAN1	gene	CTD	Gene Symbol=SPTAN1; Gene ID=6709; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Cyclosporine\|Dexamethasone\|Indomethacin\|Methotrexate\|Ozone\|Plant Extracts\|Reactive Oxygen Species\|Resveratrol\|Tobacco Smoke Pollution\|Tretinoin\|valdecoxib; Inference Score=42.75; Reference Count=161	details
PRLR	gene	CTD	Gene Symbol=PRLR; Gene ID=5618; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Chloroquine\|Curcumin\|Cyclophosphamide\|Cyclosporine\|Dexamethasone\|entinostat\|Freund's Adjuvant\|glyphosate\|Leflunomide\|Naproxen\|ochratoxin A\|Prednisolone\|Tacrolimus\|Tobacco Smoke Pollution; Inference Score=42.7; Reference Count=81	details
NOLC1	gene	CTD	Gene Symbol=NOLC1; Gene ID=9221; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Methotrexate\|Oxygen\|Ozone\|Piroxicam\|Plant Extracts\|Resveratrol\|Tretinoin; Inference Score=42.65; Reference Count=148	details
LGALS3	gene	CTD	Gene Symbol=LGALS3; Gene ID=3958; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Arsenic Trioxide\|Cyclosporine\|Dexamethasone\|Diclofenac\|entinostat\|Flurbiprofen\|Leflunomide\|Oxygen\|Ozone\|Plant Extracts\|Reactive Oxygen Species\|Resveratrol\|Sulindac\|Tobacco Smoke Pollution\|Tretinoin\|valdecoxib\|Vorinostat; Inference Score=42.63; Reference Count=44	details
FN1	gene	CTD	Gene Symbol=FN1; Gene ID=2335; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Curcumin\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|entinostat\|glyphosate\|Indomethacin\|Methotrexate\|ochratoxin A\|Ozone\|Penicillamine\|Plant Extracts\|Reactive Oxygen Species\|Resveratrol\|Tacrolimus\|Tobacco Smoke Pollution\|Tretinoin; Inference Score=42.58; Reference Count=345	details
HERC6	gene	CTD	Gene Symbol=HERC6; Gene ID=55008; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Azathioprine\|Cyclosporine\|Diclofenac\|entinostat\|Gold Sodium Thiomalate\|Methotrexate\|Methylprednisolone\|Plant Extracts\|Prednisolone\|Tretinoin\|triptolide; Inference Score=42.56; Reference Count=170	details
PPP3CA	gene	CTD	Gene Symbol=PPP3CA; Gene ID=5530; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Arsenic Trioxide\|Cyclosporine\|Dexamethasone\|entinostat\|Famotidine\|glyphosate\|Indomethacin\|Methotrexate\|Ozone\|Piroxicam\|Plant Extracts\|Tacrolimus\|Tobacco Smoke Pollution\|Tretinoin; Inference Score=42.51; Reference Count=149	details
PRDM2	gene	CTD	Gene Symbol=PRDM2; Gene ID=7799; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Cyclosporine\|Dexamethasone\|glyphosate\|Indomethacin\|Methotrexate\|Ozone\|Resveratrol\|tamibarotene\|Tobacco Smoke Pollution\|Tretinoin\|Vorinostat; Inference Score=42.47; Reference Count=147	details
RFC5	gene	CTD	Gene Symbol=RFC5; Gene ID=5985; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Azathioprine\|Cyclosporine\|Dexamethasone\|glyphosate\|Indomethacin\|ochratoxin A\|Oxygen\|Piroxicam\|Plant Extracts\|Resveratrol\|tamibarotene\|Tretinoin; Inference Score=42.47; Reference Count=48	details
AKR1C2	gene	CTD	Gene Symbol=AKR1C2; Gene ID=1646; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Arsenic Trioxide\|Aspirin\|Azathioprine\|Chlorambucil\|Cyclosporine\|entinostat\|Flurbiprofen\|Gold\|Hydrocortisone\|Indomethacin\|Mefenamic Acid\|Naproxen\|ochratoxin A\|Oxygen\|Reactive Oxygen Species\|Sulindac\|Tobacco Smoke Pollution\|Vorinostat; Inference Score=42.41; Reference Count=79	details
FGF2	gene	CTD	Gene Symbol=FGF2; Gene ID=2247; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Arsenic Trioxide\|Curcumin\|Cyclosporine\|Dexamethasone\|entinostat\|Famotidine\|Indomethacin\|Leflunomide\|Meloxicam\|Oxygen\|Ozone\|Piroxicam\|Plant Extracts\|Reactive Oxygen Species\|Resveratrol\|Thalidomide\|Tobacco Smoke Pollution\|Tretinoin\|valdecoxib; Inference Score=42.4; Reference Count=53	details
EDNRB	gene	CTD	Gene Symbol=EDNRB; Gene ID=1910; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Arsenic Trioxide\|Aspirin\|Chlorambucil\|Cyclophosphamide\|Cyclosporine\|Dexamethasone\|entinostat\|Freund's Adjuvant\|Indomethacin\|Methotrexate\|Methylprednisolone\|Nitrites\|Oxygen\|Ozone\|Tobacco Smoke Pollution\|Tretinoin\|Vorinostat; Inference Score=42.38; Reference Count=171	details
FDFT1	gene	CTD	Gene Symbol=FDFT1; Gene ID=2222; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Aspirin\|Curcumin\|Cyclosporine\|Dexamethasone\|entinostat\|glyphosate\|Indomethacin\|Leflunomide\|Oxygen\|Ozone\|Piroxicam\|Resveratrol\|Tobacco Smoke Pollution\|Tretinoin\|triptolide\|Vorinostat; Inference Score=42.38; Reference Count=60	details
ABCC1	gene	CTD	Gene Symbol=ABCC1; Gene ID=4363; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Arsenic Trioxide\|Aspirin\|Chlorambucil\|Chloroquine\|Curcumin\|Cyclophosphamide\|Cyclosporine\|Cyclosporins\|Dexamethasone\|Diclofenac\|Flurbiprofen\|Gold\|Indomethacin\|Leflunomide\|Methotrexate\|Ozone\|Plant Extracts\|Resveratrol\|Sulindac\|Tobacco Smoke Pollution; Inference Score=42.35; Reference Count=215	details
PPP1R15A	gene	CTD	Gene Symbol=PPP1R15A; Gene ID=23645; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Arsenic Trioxide\|Aspirin\|Azathioprine\|Cyclosporine\|Dexamethasone\|Diclofenac\|Indomethacin\|Leflunomide\|Methotrexate\|Oxygen\|Pesticides\|Piroxicam\|Plant Extracts\|Tacrolimus\|tamibarotene\|Thalidomide\|Tobacco Smoke Pollution\|Tretinoin; Inference Score=42.34; Reference Count=187	details
AMD1	gene	CTD	Gene Symbol=AMD1; Gene ID=262; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Cyclosporine\|Dexamethasone\|Indomethacin\|Leflunomide\|Ozone\|Resveratrol\|Sulindac\|tamibarotene\|Tobacco Smoke Pollution\|Tretinoin; Inference Score=42.3; Reference Count=53	details
AMIGO2	gene	CTD	Gene Symbol=AMIGO2; Gene ID=347902; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Azathioprine\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Gold Sodium Thiomalate\|Indomethacin\|Methotrexate\|Methylprednisolone\|ochratoxin A\|Piroxicam\|Plant Extracts\|Prednisolone\|Tretinoin; Inference Score=42.3; Reference Count=178	details
PIM1	gene	CTD	Gene Symbol=PIM1; Gene ID=5292; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Antirheumatic Agents\|Arsenic Trioxide\|Azathioprine\|Cyclosporine\|Dexamethasone\|entinostat\|glyphosate\|Leflunomide\|Methotrexate\|Oxygen\|Plant Extracts\|Resveratrol\|tamibarotene\|Thalidomide\|Tobacco Smoke Pollution\|Tretinoin; Inference Score=42.3; Reference Count=152	details