|
rs1160542 |
SNP |
PedAM |
snpId=rs1160542; pubmedId=20498205; geneId=958; geneSymbol=CD40; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Eight markers (ie, rs1160542 (AFF3), rs1678542 (KIF5A), rs2476601 (PTPN22), rs3087243 (CTLA4), rs4810485 (CD40), rs5029937 (6q23), rs10760130 (TRAF1/C5) and rs7574865 (STAT4)) were significantly associated with RA by meta-analysis.; score=0.277186332; Year=2010; geneSymbol_dbSNP=LINC01104; CHROMOSOME=2; POS=100215693; REF=G; ALT=A |
details
|
|
|
rs1160542 |
SNP |
PedAM |
snpId=rs1160542; pubmedId=20498205; geneId=7185; geneSymbol=TRAF1; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Eight markers (ie, rs1160542 (AFF3), rs1678542 (KIF5A), rs2476601 (PTPN22), rs3087243 (CTLA4), rs4810485 (CD40), rs5029937 (6q23), rs10760130 (TRAF1/C5) and rs7574865 (STAT4)) were significantly associated with RA by meta-analysis.; score=0.311201237; Year=2010; geneSymbol_dbSNP=LINC01104; CHROMOSOME=2; POS=100215693; REF=G; ALT=A |
details
|
|
|
rs11676922 |
SNP |
PedAM |
snpId=rs11676922; pubmedId=20453842; geneId=3899; geneSymbol=AFF3; diseaseId=umls:C0003873; sourceId=GAD; sentence=[We also refined associations at two established rheumatoid arthritis risk loci (IL2RA and CCL21) and confirmed the association at AFF3.]; score=0.129001189; Year=2010; geneSymbol_dbSNP=NA; CHROMOSOME=2; POS=100190478; REF=T; ALT=A |
details
|
|
|
rs11889341 |
SNP |
PedAM |
snpId=rs11889341; pubmedId=24390342; geneId=6775; geneSymbol=STAT4; diseaseId=umls:C0003873; sourceId=GWASCAT; sentence=Genetics of rheumatoid arthritis contributes to biology and drug discovery.; score=0.316739695; Year=2013; geneSymbol_dbSNP=STAT4; CHROMOSOME=2; POS=191079016; REF=C; ALT=T |
details
|
|
|
rs11900673 |
SNP |
PedAM |
snpId=rs11900673; pubmedId=22446963; geneId=10678; geneSymbol=B3GNT2; diseaseId=umls:C0003873; sourceId=GAD; sentence=[Our study identified nine loci newly associated with rheumatoid arthritis at a threshold of P < 5.0 A 10(-8), including B3GNT2, ANXA3, CSF2, CD83, NFKBIE, ARID5B, PDE2A-ARAP1, PLD4 and PTPN2.]; score=0.123181358; Year=2012; geneSymbol_dbSNP=NA; CHROMOSOME=2; POS=62225526; REF=C; ALT=T |
details
|
|
|
rs11900673 |
SNP |
PedAM |
snpId=rs11900673; pubmedId=23577190; geneId=84159; geneSymbol=ARID5B; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Genetic factors regarded as putative risk factors were RA-susceptible polymorphisms identified by the Japanese GWAS meta-analysis, including HLA-DRB1 (shared epitope, SE), rs2240340 (PADI4), rs2230926 (TNFAIP3), rs3093024 (CCR6), rs11900673 (B3GNT2), rs2867461 (ANXA3), rs657075 (CSF2), rs12529514 (CD83), rs2233434 (NFKBIE), rs10821944 (ARID5B), rs3781913 (PDE2A-ARAP1), rs2841277 (PLD4) and rs2847297 (PTPN2).; score=0.242909916; Year=2013; geneSymbol_dbSNP=NA; CHROMOSOME=2; POS=62225526; REF=C; ALT=T |
details
|
|
|
rs11900673 |
SNP |
PedAM |
snpId=rs11900673; pubmedId=23577190; geneId=116985; geneSymbol=ARAP1; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Genetic factors regarded as putative risk factors were RA-susceptible polymorphisms identified by the Japanese GWAS meta-analysis, including HLA-DRB1 (shared epitope, SE), rs2240340 (PADI4), rs2230926 (TNFAIP3), rs3093024 (CCR6), rs11900673 (B3GNT2), rs2867461 (ANXA3), rs657075 (CSF2), rs12529514 (CD83), rs2233434 (NFKBIE), rs10821944 (ARID5B), rs3781913 (PDE2A-ARAP1), rs2841277 (PLD4) and rs2847297 (PTPN2).; score=0.000271442; Year=2013; geneSymbol_dbSNP=NA; CHROMOSOME=2; POS=62225526; REF=C; ALT=T |
details
|
|
|
rs11900673 |
SNP |
PedAM |
snpId=rs11900673; pubmedId=23577190; geneId=5771; geneSymbol=PTPN2; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Genetic factors regarded as putative risk factors were RA-susceptible polymorphisms identified by the Japanese GWAS meta-analysis, including HLA-DRB1 (shared epitope, SE), rs2240340 (PADI4), rs2230926 (TNFAIP3), rs3093024 (CCR6), rs11900673 (B3GNT2), rs2867461 (ANXA3), rs657075 (CSF2), rs12529514 (CD83), rs2233434 (NFKBIE), rs10821944 (ARID5B), rs3781913 (PDE2A-ARAP1), rs2841277 (PLD4) and rs2847297 (PTPN2).; score=0.248458305; Year=2013; geneSymbol_dbSNP=NA; CHROMOSOME=2; POS=62225526; REF=C; ALT=T |
details
|
|
|
rs11900673 |
SNP |
PedAM |
snpId=rs11900673; pubmedId=23577190; geneId=1437; geneSymbol=CSF2; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Genetic factors regarded as putative risk factors were RA-susceptible polymorphisms identified by the Japanese GWAS meta-analysis, including HLA-DRB1 (shared epitope, SE), rs2240340 (PADI4), rs2230926 (TNFAIP3), rs3093024 (CCR6), rs11900673 (B3GNT2), rs2867461 (ANXA3), rs657075 (CSF2), rs12529514 (CD83), rs2233434 (NFKBIE), rs10821944 (ARID5B), rs3781913 (PDE2A-ARAP1), rs2841277 (PLD4) and rs2847297 (PTPN2).; score=0.129424521; Year=2013; geneSymbol_dbSNP=NA; CHROMOSOME=2; POS=62225526; REF=C; ALT=T |
details
|
|
|
rs11900673 |
SNP |
PedAM |
snpId=rs11900673; pubmedId=23577190; geneId=10678; geneSymbol=B3GNT2; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Genetic factors regarded as putative risk factors were RA-susceptible polymorphisms identified by the Japanese GWAS meta-analysis, including HLA-DRB1 (shared epitope, SE), rs2240340 (PADI4), rs2230926 (TNFAIP3), rs3093024 (CCR6), rs11900673 (B3GNT2), rs2867461 (ANXA3), rs657075 (CSF2), rs12529514 (CD83), rs2233434 (NFKBIE), rs10821944 (ARID5B), rs3781913 (PDE2A-ARAP1), rs2841277 (PLD4) and rs2847297 (PTPN2).; score=0.123181358; Year=2013; geneSymbol_dbSNP=NA; CHROMOSOME=2; POS=62225526; REF=C; ALT=T |
details
|
|
|
rs11900673 |
SNP |
PedAM |
snpId=rs11900673; pubmedId=23577190; geneId=7128; geneSymbol=TNFAIP3; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Genetic factors regarded as putative risk factors were RA-susceptible polymorphisms identified by the Japanese GWAS meta-analysis, including HLA-DRB1 (shared epitope, SE), rs2240340 (PADI4), rs2230926 (TNFAIP3), rs3093024 (CCR6), rs11900673 (B3GNT2), rs2867461 (ANXA3), rs657075 (CSF2), rs12529514 (CD83), rs2233434 (NFKBIE), rs10821944 (ARID5B), rs3781913 (PDE2A-ARAP1), rs2841277 (PLD4) and rs2847297 (PTPN2).; score=0.167568474; Year=2013; geneSymbol_dbSNP=NA; CHROMOSOME=2; POS=62225526; REF=C; ALT=T |
details
|
|
|
rs11900673 |
SNP |
PedAM |
snpId=rs11900673; pubmedId=23577190; geneId=122618; geneSymbol=PLD4; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Genetic factors regarded as putative risk factors were RA-susceptible polymorphisms identified by the Japanese GWAS meta-analysis, including HLA-DRB1 (shared epitope, SE), rs2240340 (PADI4), rs2230926 (TNFAIP3), rs3093024 (CCR6), rs11900673 (B3GNT2), rs2867461 (ANXA3), rs657075 (CSF2), rs12529514 (CD83), rs2233434 (NFKBIE), rs10821944 (ARID5B), rs3781913 (PDE2A-ARAP1), rs2841277 (PLD4) and rs2847297 (PTPN2).; score=0.242638474; Year=2013; geneSymbol_dbSNP=NA; CHROMOSOME=2; POS=62225526; REF=C; ALT=T |
details
|
|
|
rs11900673 |
SNP |
PedAM |
snpId=rs11900673; pubmedId=23577190; geneId=306; geneSymbol=ANXA3; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Genetic factors regarded as putative risk factors were RA-susceptible polymorphisms identified by the Japanese GWAS meta-analysis, including HLA-DRB1 (shared epitope, SE), rs2240340 (PADI4), rs2230926 (TNFAIP3), rs3093024 (CCR6), rs11900673 (B3GNT2), rs2867461 (ANXA3), rs657075 (CSF2), rs12529514 (CD83), rs2233434 (NFKBIE), rs10821944 (ARID5B), rs3781913 (PDE2A-ARAP1), rs2841277 (PLD4) and rs2847297 (PTPN2).; score=0.242638474; Year=2013; geneSymbol_dbSNP=NA; CHROMOSOME=2; POS=62225526; REF=C; ALT=T |
details
|
|
|
rs11900673 |
SNP |
PedAM |
snpId=rs11900673; pubmedId=23577190; geneId=9034; geneSymbol=CCRL2; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Genetic factors regarded as putative risk factors were RA-susceptible polymorphisms identified by the Japanese GWAS meta-analysis, including HLA-DRB1 (shared epitope, SE), rs2240340 (PADI4), rs2230926 (TNFAIP3), rs3093024 (CCR6), rs11900673 (B3GNT2), rs2867461 (ANXA3), rs657075 (CSF2), rs12529514 (CD83), rs2233434 (NFKBIE), rs10821944 (ARID5B), rs3781913 (PDE2A-ARAP1), rs2841277 (PLD4) and rs2847297 (PTPN2).; score=0.005710211; Year=2013; geneSymbol_dbSNP=NA; CHROMOSOME=2; POS=62225526; REF=C; ALT=T |
details
|
|
|
rs11900673 |
SNP |
PedAM |
snpId=rs11900673; pubmedId=23577190; geneId=9308; geneSymbol=CD83; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Genetic factors regarded as putative risk factors were RA-susceptible polymorphisms identified by the Japanese GWAS meta-analysis, including HLA-DRB1 (shared epitope, SE), rs2240340 (PADI4), rs2230926 (TNFAIP3), rs3093024 (CCR6), rs11900673 (B3GNT2), rs2867461 (ANXA3), rs657075 (CSF2), rs12529514 (CD83), rs2233434 (NFKBIE), rs10821944 (ARID5B), rs3781913 (PDE2A-ARAP1), rs2841277 (PLD4) and rs2847297 (PTPN2).; score=0.123267234; Year=2013; geneSymbol_dbSNP=NA; CHROMOSOME=2; POS=62225526; REF=C; ALT=T |
details
|
|
|
rs11937061 |
SNP |
PedAM |
snpId=rs11937061; pubmedId=22491018; geneId=901; geneSymbol=CCNG2; diseaseId=umls:C0003873; sourceId=GAD; sentence=[Genome-wide association analysis implicates the involvement of eight loci with response to tocilizumab for the treatment of rheumatoid arthritis.]; score=0.002367032; Year=2013; geneSymbol_dbSNP=NA; CHROMOSOME=4; POS=77215780; REF=G; ALT=T |
details
|
|
|
rs11986055 |
SNP |
PedAM |
snpId=rs11986055; pubmedId=20448286; geneId=3551; geneSymbol=IKBKB; diseaseId=umls:C0003873; sourceId=GAD; sentence=[Several SNPs mapping to the TLR and NFkappaB signalling systems demonstrated association with anti-TNF response as a whole and, in particular, with response to etanercept. Validation of these findings in an independent cohort is now warranted.]; score=0.00554839; Year=2010; geneSymbol_dbSNP=IKBKB; CHROMOSOME=8; POS=42277660; REF=A; ALT=C |
details
|
|
|
rs12083537 |
SNP |
PedAM |
snpId=rs12083537; pubmedId=24978393; geneId=3570; geneSymbol=IL6R; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Interleukin-6-receptor polymorphisms rs12083537, rs2228145, and rs4329505 as predictors of response to tocilizumab in rheumatoid arthritis.; score=0.247719925; Year=2014; geneSymbol_dbSNP=IL6R;LOC101928101; CHROMOSOME=1; POS=154408627; REF=A; ALT=G |
details
|
|
|
rs12109285 |
SNP |
PedAM |
snpId=rs12109285; pubmedId=22491018; geneId=728411; geneSymbol=GUSBP1; diseaseId=umls:C0003873; sourceId=GAD; sentence=[Genome-wide association analysis implicates the involvement of eight loci with response to tocilizumab for the treatment of rheumatoid arthritis.]; score=0.002367032; Year=2013; geneSymbol_dbSNP=LOC105374684; CHROMOSOME=5; POS=21749239; REF=T; ALT=A,C |
details
|
|
|
rs12131057 |
SNP |
PedAM |
snpId=rs12131057; pubmedId=20453842; geneId=5453; geneSymbol=POU3F1; diseaseId=umls:C0003873; sourceId=GAD; sentence=[Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.]; score=0.122367032; Year=2010; geneSymbol_dbSNP=LOC105378654; CHROMOSOME=1; POS=38158457; REF=G; ALT=A |
details
|
|
