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rs17435 |
SNP |
PedAM |
snpId=rs17435; pubmedId=19714582; geneId=55024; geneSymbol=BANK1; diseaseId=umls:C0003873; sourceId=BeFree; sentence=A characteristic single-nucleotide polymorphism (SNP) in each of 9 genetic factors, ITGAM (rs1143679), C8orf13-BLK (rs13277113), TYK2 (rs2304256), 1q25.1 (rs10798269), PXK (rs6445975), KIAA1542 (rs4963128), MECP2 (rs17435), BANK1 (rs17266594), and LY9 (rs509749), was studied in 1,635 patients with RA and 1,906 control subjects from Spain.; score=0.003181358; Year=2009; geneSymbol_dbSNP=MECP2; CHROMOSOME=X; POS=154046529; REF=T; ALT=A |
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rs17435 |
SNP |
PedAM |
snpId=rs17435; pubmedId=19714582; geneId=3684; geneSymbol=ITGAM; diseaseId=umls:C0003873; sourceId=BeFree; sentence=A characteristic single-nucleotide polymorphism (SNP) in each of 9 genetic factors, ITGAM (rs1143679), C8orf13-BLK (rs13277113), TYK2 (rs2304256), 1q25.1 (rs10798269), PXK (rs6445975), KIAA1542 (rs4963128), MECP2 (rs17435), BANK1 (rs17266594), and LY9 (rs509749), was studied in 1,635 patients with RA and 1,906 control subjects from Spain.; score=0.000814326; Year=2009; geneSymbol_dbSNP=MECP2; CHROMOSOME=X; POS=154046529; REF=T; ALT=A |
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rs17435 |
SNP |
PedAM |
snpId=rs17435; pubmedId=19714582; geneId=4204; geneSymbol=MECP2; diseaseId=umls:C0003873; sourceId=BeFree; sentence=A characteristic single-nucleotide polymorphism (SNP) in each of 9 genetic factors, ITGAM (rs1143679), C8orf13-BLK (rs13277113), TYK2 (rs2304256), 1q25.1 (rs10798269), PXK (rs6445975), KIAA1542 (rs4963128), MECP2 (rs17435), BANK1 (rs17266594), and LY9 (rs509749), was studied in 1,635 patients with RA and 1,906 control subjects from Spain.; score=0.120814326; Year=2009; geneSymbol_dbSNP=MECP2; CHROMOSOME=X; POS=154046529; REF=T; ALT=A |
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rs1799930 |
SNP |
PedAM |
snpId=rs1799930; pubmedId=17985847; geneId=6288; geneSymbol=SAA1; diseaseId=umls:C0003873; sourceId=BeFree; sentence=In this study, the six polymorphisms associated with rheumatoid arthritis (RA), N-acetyltransferase2 (NAT2) gene polymorphisms T341C, G590A, and G857A, methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms C677T and A1298C, and serum amyloid A1 (SAA1) gene promoter polymorphism C-13T were simultaneously detected by the electrochemical DNA chip and the loop-mediated isothermal amplification (LAMP) method, which is a novel technique for DNA amplification.; score=0.016425927; Year=2007; geneSymbol_dbSNP=NAT2; CHROMOSOME=8; POS=18400593; REF=G; ALT=A |
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rs1799930 |
SNP |
PedAM |
snpId=rs1799930; pubmedId=17985847; geneId=4524; geneSymbol=MTHFR; diseaseId=umls:C0003873; sourceId=BeFree; sentence=In this study, the six polymorphisms associated with rheumatoid arthritis (RA), N-acetyltransferase2 (NAT2) gene polymorphisms T341C, G590A, and G857A, methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms C677T and A1298C, and serum amyloid A1 (SAA1) gene promoter polymorphism C-13T were simultaneously detected by the electrochemical DNA chip and the loop-mediated isothermal amplification (LAMP) method, which is a novel technique for DNA amplification.; score=0.20430773; Year=2007; geneSymbol_dbSNP=NAT2; CHROMOSOME=8; POS=18400593; REF=G; ALT=A |
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rs1799930 |
SNP |
PedAM |
snpId=rs1799930; pubmedId=17985847; geneId=10; geneSymbol=NAT2; diseaseId=umls:C0003873; sourceId=BeFree; sentence=In this study, the six polymorphisms associated with rheumatoid arthritis (RA), N-acetyltransferase2 (NAT2) gene polymorphisms T341C, G590A, and G857A, methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms C677T and A1298C, and serum amyloid A1 (SAA1) gene promoter polymorphism C-13T were simultaneously detected by the electrochemical DNA chip and the loop-mediated isothermal amplification (LAMP) method, which is a novel technique for DNA amplification.; score=0.019726837; Year=2007; geneSymbol_dbSNP=NAT2; CHROMOSOME=8; POS=18400593; REF=G; ALT=A |
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rs1799931 |
SNP |
PedAM |
snpId=rs1799931; pubmedId=17985847; geneId=10; geneSymbol=NAT2; diseaseId=umls:C0003873; sourceId=BeFree; sentence=In this study, the six polymorphisms associated with rheumatoid arthritis (RA), N-acetyltransferase2 (NAT2) gene polymorphisms T341C, G590A, and G857A, methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms C677T and A1298C, and serum amyloid A1 (SAA1) gene promoter polymorphism C-13T were simultaneously detected by the electrochemical DNA chip and the loop-mediated isothermal amplification (LAMP) method, which is a novel technique for DNA amplification.; score=0.019726837; Year=2007; geneSymbol_dbSNP=NAT2; CHROMOSOME=8; POS=18400860; REF=G; ALT=A |
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rs1799931 |
SNP |
PedAM |
snpId=rs1799931; pubmedId=17985847; geneId=4524; geneSymbol=MTHFR; diseaseId=umls:C0003873; sourceId=BeFree; sentence=In this study, the six polymorphisms associated with rheumatoid arthritis (RA), N-acetyltransferase2 (NAT2) gene polymorphisms T341C, G590A, and G857A, methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms C677T and A1298C, and serum amyloid A1 (SAA1) gene promoter polymorphism C-13T were simultaneously detected by the electrochemical DNA chip and the loop-mediated isothermal amplification (LAMP) method, which is a novel technique for DNA amplification.; score=0.20430773; Year=2007; geneSymbol_dbSNP=NAT2; CHROMOSOME=8; POS=18400860; REF=G; ALT=A |
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rs1799931 |
SNP |
PedAM |
snpId=rs1799931; pubmedId=17985847; geneId=6288; geneSymbol=SAA1; diseaseId=umls:C0003873; sourceId=BeFree; sentence=In this study, the six polymorphisms associated with rheumatoid arthritis (RA), N-acetyltransferase2 (NAT2) gene polymorphisms T341C, G590A, and G857A, methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms C677T and A1298C, and serum amyloid A1 (SAA1) gene promoter polymorphism C-13T were simultaneously detected by the electrochemical DNA chip and the loop-mediated isothermal amplification (LAMP) method, which is a novel technique for DNA amplification.; score=0.016425927; Year=2007; geneSymbol_dbSNP=NAT2; CHROMOSOME=8; POS=18400860; REF=G; ALT=A |
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rs1800471 |
SNP |
PedAM |
snpId=rs1800471; pubmedId=21113716; geneId=7040; geneSymbol=TGFB1; diseaseId=umls:C0003873; sourceId=BeFree; sentence=The functional class evaluated in rheumatoid arthritis is associated with soluble TGF-¦Â1 serum levels but not with G915C (Arg25Pro) TGF-¦Â1 polymorphism.; score=0.02372252; Year=2012; geneSymbol_dbSNP=TGFB1; CHROMOSOME=19; POS=41352971; REF=C; ALT=G |
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rs1800629 |
SNP |
PedAM |
snpId=rs1800629; pubmedId=22927710; geneId=4524; geneSymbol=MTHFR; diseaseId=umls:C0003873; sourceId=BeFree; sentence=In this regard, besides a strong association between the HLA-DRB104 shared epitope alleles and both endothelial dysfunction, an early step in the atherosclerotic process, and clinically evident CV disease, other polymorphisms belonging to genes implicated in inflammatory and metabolic pathways, located inside and outside the HLA region, such as the 308 variant (G > A, rs1800629) of the TNFA locus, the rs1801131 polymorphism (A > C; position + 1298) of the MTHFR locus, or a deletion of 32 base pairs on the CCR5 gene, seem to be associated with the risk of CV disease in patients with RA.; score=0.20430773; Year=2012; geneSymbol_dbSNP=TNF; CHROMOSOME=6; POS=31575254; REF=G; ALT=A |
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rs1800629 |
SNP |
PedAM |
snpId=rs1800629; pubmedId=22927710; geneId=1234; geneSymbol=CCR5; diseaseId=umls:C0003873; sourceId=BeFree; sentence=In this regard, besides a strong association between the HLA-DRB104 shared epitope alleles and both endothelial dysfunction, an early step in the atherosclerotic process, and clinically evident CV disease, other polymorphisms belonging to genes implicated in inflammatory and metabolic pathways, located inside and outside the HLA region, such as the 308 variant (G > A, rs1800629) of the TNFA locus, the rs1801131 polymorphism (A > C; position + 1298) of the MTHFR locus, or a deletion of 32 base pairs on the CCR5 gene, seem to be associated with the risk of CV disease in patients with RA.; score=0.031985329; Year=2012; geneSymbol_dbSNP=TNF; CHROMOSOME=6; POS=31575254; REF=G; ALT=A |
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rs1800629 |
SNP |
PedAM |
snpId=rs1800629; pubmedId=21420089; geneId=7124; geneSymbol=TNF; diseaseId=umls:C0003873; sourceId=BeFree; sentence=TNFA -308 (rs1800629) polymorphism is associated with a higher risk of cardiovascular disease in patients with rheumatoid arthritis.; score=0.425384406; Year=2011; geneSymbol_dbSNP=TNF; CHROMOSOME=6; POS=31575254; REF=G; ALT=A |
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rs1800629 |
SNP |
PedAM |
snpId=rs1800629; pubmedId=22927710; geneId=7124; geneSymbol=TNF; diseaseId=umls:C0003873; sourceId=BeFree; sentence=In this regard, besides a strong association between the HLA-DRB104 shared epitope alleles and both endothelial dysfunction, an early step in the atherosclerotic process, and clinically evident CV disease, other polymorphisms belonging to genes implicated in inflammatory and metabolic pathways, located inside and outside the HLA region, such as the 308 variant (G > A, rs1800629) of the TNFA locus, the rs1801131 polymorphism (A > C; position + 1298) of the MTHFR locus, or a deletion of 32 base pairs on the CCR5 gene, seem to be associated with the risk of CV disease in patients with RA.; score=0.425384406; Year=2012; geneSymbol_dbSNP=TNF; CHROMOSOME=6; POS=31575254; REF=G; ALT=A |
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rs1800629 |
SNP |
PedAM |
snpId=rs1800629; pubmedId=22927710; geneId=3123; geneSymbol=HLA-DRB1; diseaseId=umls:C0003873; sourceId=BeFree; sentence=In this regard, besides a strong association between the HLA-DRB104 shared epitope alleles and both endothelial dysfunction, an early step in the atherosclerotic process, and clinically evident CV disease, other polymorphisms belonging to genes implicated in inflammatory and metabolic pathways, located inside and outside the HLA region, such as the 308 variant (G > A, rs1800629) of the TNFA locus, the rs1801131 polymorphism (A > C; position + 1298) of the MTHFR locus, or a deletion of 32 base pairs on the CCR5 gene, seem to be associated with the risk of CV disease in patients with RA.; score=0.36; Year=2012; geneSymbol_dbSNP=TNF; CHROMOSOME=6; POS=31575254; REF=G; ALT=A |
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rs1800790 |
SNP |
PedAM |
snpId=rs1800790; pubmedId=22267327; geneId=1401; geneSymbol=CRP; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Genotype FGB -455G>A (rs1800790) was associated with CRP elevations (¡Ý 10 mg/l) in both cohorts (RA, OR per allele 0.69, p=0.0007/P(adj)<0.015; non-RA, OR 0.70, p=0.0004/p(adj)<0.02; combined, OR 0.69, p<10(-5)/p(adj)=0.001).; score=0.232003854; Year=2012; geneSymbol_dbSNP=FGB; CHROMOSOME=4; POS=154562556; REF=G; ALT=A |
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rs1800795 |
SNP |
PedAM |
snpId=rs1800795; pubmedId=25566937; geneId=3569; geneSymbol=IL6; diseaseId=umls:C0003873; sourceId=BeFree; sentence=No associations were found for rs1800795 (IL-6), rs1800896 (IL-10) and rs7528684 (FCRL3) in the total RA-population and after stratification for ACPA.; score=0.212623944; Year=2014; geneSymbol_dbSNP=IL6;LOC541472; CHROMOSOME=7; POS=22727026; REF=C; ALT=G |
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rs1800795 |
SNP |
PedAM |
snpId=rs1800795; pubmedId=25566937; geneId=115352; geneSymbol=FCRL3; diseaseId=umls:C0003873; sourceId=BeFree; sentence=No associations were found for rs1800795 (IL-6), rs1800896 (IL-10) and rs7528684 (FCRL3) in the total RA-population and after stratification for ACPA.; score=0.034881432; Year=2014; geneSymbol_dbSNP=IL6;LOC541472; CHROMOSOME=7; POS=22727026; REF=C; ALT=G |
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rs1800795 |
SNP |
PedAM |
snpId=rs1800795; pubmedId=25566937; geneId=3586; geneSymbol=IL10; diseaseId=umls:C0003873; sourceId=BeFree; sentence=No associations were found for rs1800795 (IL-6), rs1800896 (IL-10) and rs7528684 (FCRL3) in the total RA-population and after stratification for ACPA.; score=0.203492066; Year=2014; geneSymbol_dbSNP=IL6;LOC541472; CHROMOSOME=7; POS=22727026; REF=C; ALT=G |
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rs1800896 |
SNP |
PedAM |
snpId=rs1800896; pubmedId=25566937; geneId=115352; geneSymbol=FCRL3; diseaseId=umls:C0003873; sourceId=BeFree; sentence=No associations were found for rs1800795 (IL-6), rs1800896 (IL-10) and rs7528684 (FCRL3) in the total RA-population and after stratification for ACPA.; score=0.034881432; Year=2014; geneSymbol_dbSNP=IL10; CHROMOSOME=1; POS=206773552; REF=T; ALT=C |
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