RABC

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Biomarkers name	Biomarker Type	Source database	Information	Details
IL4	gene	CTD	Gene Symbol=IL4; Gene ID=3565; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Adjuvants, Immunologic\|Air Pollutants\|Antigens\|Arsenic Trioxide\|Aspirin\|Azathioprine\|Chlorambucil\|Chloroquine\|Curcumin\|Cyclophosphamide\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|Dinoprostone\|Edaravone\|Famotidine\|Freund's Adjuvant\|gamisopoonghwanghyul-tang\|Gold Sodium Thiomalate\|Hydrocortisone\|Indomethacin\|Leflunomide\|Levamisole\|Methotrexate\|Methylprednisolone\|Naproxen\|Nitrites\|ochratoxin A\|Oxygen\|Ozone\|Penicillamine\|Plant Extracts\|Prednisolone\|Prednisone\|Reactive Oxygen Species\|Resveratrol\|Sulfasalazine\|Tacrolimus\|tamibarotene\|Thalidomide\|thymoquinone\|Tobacco Smoke Pollution\|tofacitinib\|Tretinoin; Inference Score=102; Reference Count=449	details
SELL	gene	CTD	Gene Symbol=SELL; Gene ID=6402; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=aceclofenac\|Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Aspirin\|Curcumin\|Cyclosporine\|Diclofenac\|Enalapril\|Flurbiprofen\|Indomethacin\|Ketoprofen\|Mefenamic Acid\|Meloxicam\|Methotrexate\|Nabumetone\|Naproxen\|Oxygen\|Ozone\|Phenylbutazone\|Piroxicam\|Plant Extracts\|Resveratrol\|tamibarotene\|Thalidomide\|Tretinoin\|Vorinostat; Inference Score=88.52; Reference Count=184	details
STAT3	gene	CTD	Gene Symbol=STAT3; Gene ID=6774; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Antigens\|Antirheumatic Agents\|Arsenic Trioxide\|Aspartame\|Aspirin\|Auranofin\|Azathioprine\|Curcumin\|Cyclophosphamide\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|Dinoprostone\|Enalapril\|entinostat\|Freund's Adjuvant\|glyphosate\|Gold\|Indomethacin\|Leflunomide\|Maneb\|Methotrexate\|ochratoxin A\|Oxygen\|Ozone\|Piroxicam\|Plant Extracts\|Reactive Oxygen Species\|Resveratrol\|Sulfasalazine\|Sulindac\|Tacrolimus\|Thalidomide\|thymoquinone\|Tobacco Smoke Pollution\|tofacitinib\|Tretinoin\|triptolide\|valdecoxib\|Vorinostat; Inference Score=87.77; Reference Count=258	details
ICAM1	gene	CTD	Gene Symbol=ICAM1; Gene ID=3383; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Adjuvants, Immunologic\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Chloroquine\|Curcumin\|Cyclophosphamide\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|Dinoprostone\|Edaravone\|Enalapril\|entinostat\|Etoricoxib\|Famotidine\|Flurbiprofen\|Freund's Adjuvant\|Glucocorticoids\|Gold Compounds\|Hydrocortisone\|Indomethacin\|Leflunomide\|Maneb\|Methotrexate\|Minocycline\|ochratoxin A\|Oxygen\|Ozone\|Plant Extracts\|Reactive Oxygen Species\|Resveratrol\|Sulfasalazine\|Sulindac\|Tacrolimus\|Thalidomide\|Tobacco Smoke Pollution\|Tretinoin\|triptolide\|Vorinostat; Inference Score=84.05; Reference Count=248	details
RELA	gene	CTD	Gene Symbol=RELA; Gene ID=5970; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Adjuvants, Immunologic\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Auranofin\|Chloroquine\|Curcumin\|Cyclophosphamide\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|Dinoprostone\|Edaravone\|Enalapril\|entinostat\|Famotidine\|Flurbiprofen\|Freund's Adjuvant\|glyphosate\|Gold\|Gold Compounds\|GW 506033X\|Hydrocortisone\|Hydroxychloroquine\|Indomethacin\|Levamisole\|mancozeb\|Maneb\|Methotrexate\|Methylprednisolone\|Minocycline\|Naproxen\|ochratoxin A\|Oxygen\|Ozone\|Phenylbutazone\|Plant Extracts\|Resveratrol\|Salicylates\|Sulfasalazine\|Sulindac\|Tacrolimus\|tamibarotene\|Thalidomide\|thymoquinone\|Tobacco Smoke Pollution\|Tretinoin\|triptolide\|Vorinostat; Inference Score=81.89; Reference Count=283	details
FAS	gene	CTD	Gene Symbol=FAS; Gene ID=355; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Angiotensin-Converting Enzyme Inhibitors\|Arsenic Trioxide\|Aspirin\|Aurothioglucose\|Chlorambucil\|Curcumin\|Cyclophosphamide\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|Dinoprostone\|entinostat\|glyphosate\|Gold\|Gold Compounds\|Hydrocortisone\|Hydroxychloroquine\|mancozeb\|Maneb\|Methotrexate\|Naproxen\|ochratoxin A\|Oxygen\|Ozone\|Penicillamine\|Plant Extracts\|Reactive Oxygen Species\|Resveratrol\|Tacrolimus\|tamibarotene\|Thalidomide\|Tobacco Smoke Pollution\|Tretinoin\|triptolide\|Vorinostat; Inference Score=79.55; Reference Count=354	details
CASP9	gene	CTD	Gene Symbol=CASP9; Gene ID=842; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Aspartame\|Aspirin\|Auranofin\|Chloroquine\|chloroquine diphosphate\|Curcumin\|Cyclophosphamide\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|Dinoprostone\|Edaravone\|Enalapril\|entinostat\|Freund's Adjuvant\|glyphosate\|Gold\|Gold Compounds\|Indomethacin\|Leflunomide\|mancozeb\|Maneb\|Meloxicam\|Methotrexate\|Minocycline\|ochratoxin A\|Oxygen\|Ozone\|Penicillamine\|Plant Extracts\|Quinacrine\|Reactive Oxygen Species\|Resveratrol\|Sulfasalazine\|Sulindac\|Tacrolimus\|tamibarotene\|Thalidomide\|thymoquinone\|Tobacco Smoke Pollution\|Tretinoin\|triptolide\|Vorinostat; Inference Score=77.68; Reference Count=425	details
NOS2	gene	CTD	Gene Symbol=NOS2; Gene ID=4843; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Arsenic Trioxide\|Aspirin\|Azathioprine\|Chloroquine\|Curcumin\|Cyclophosphamide\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|Dinoprostone\|Edaravone\|Enalapril\|entinostat\|Flurbiprofen\|Freund's Adjuvant\|Gold\|Gold Sodium Thiomalate\|GW 506033X\|Hydrocortisone\|Hydroxychloroquine\|Indomethacin\|Leflunomide\|mancozeb\|Maneb\|Methotrexate\|Methylprednisolone\|Minocycline\|Naproxen\|Nitrites\|ochratoxin A\|Oxygen\|Ozone\|Penicillamine\|Pesticides\|Plant Extracts\|Prednisolone\|Reactive Oxygen Species\|Resveratrol\|Sulfasalazine\|Tacrolimus\|tamibarotene\|Thalidomide\|Tiopronin\|Tobacco Smoke Pollution\|Tretinoin\|Vorinostat; Inference Score=76.79; Reference Count=442	details
BAK1	gene	CTD	Gene Symbol=BAK1; Gene ID=578; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Auranofin\|Curcumin\|deoxynivalenol\|Dexamethasone\|Diclofenac\|Dinoprostone\|entinostat\|Freund's Adjuvant\|Gold\|Indomethacin\|Levamisole\|Maneb\|Methotrexate\|Minocycline\|ochratoxin A\|Organogold Compounds\|Oxygen\|Plant Extracts\|Resveratrol\|Sulindac\|tamibarotene\|Tobacco Smoke Pollution\|Tretinoin\|triptolide\|Vorinostat; Inference Score=76.01; Reference Count=208	details
CCL2	gene	CTD	Gene Symbol=CCL2; Gene ID=6347; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Adjuvants, Immunologic\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Aspartame\|Aspirin\|baricitinib\|Betamethasone\|bucillamine\|Chloroquine\|Curcumin\|Cyclophosphamide\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|Dinoprostone\|Edaravone\|Enalapril\|entinostat\|Freund's Adjuvant\|Gold\|Gold Compounds\|Hydrocortisone\|Hydroxychloroquine\|Indomethacin\|Maneb\|Methotrexate\|Minocycline\|Naproxen\|Oxygen\|Ozone\|Plant Extracts\|Prednisolone\|Reactive Oxygen Species\|Resveratrol\|Sulfasalazine\|Tacrolimus\|Thalidomide\|Tiopronin\|Tobacco Smoke Pollution\|tofacitinib\|Tretinoin\|triptolide\|Vorinostat; Inference Score=75.59; Reference Count=270	details
ALB	gene	CTD	Gene Symbol=ALB; Gene ID=213; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Anti-Inflammatory Agents, Non-Steroidal\|Arsenic Trioxide\|Aspirin\|Auranofin\|Azathioprine\|benoxaprofen\|chloroquine diphosphate\|Curcumin\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|entinostat\|Fenoprofen\|Flurbiprofen\|glyphosate\|Gold\|Indomethacin\|Ketoprofen\|mancozeb\|Mefenamic Acid\|Methotrexate\|Naproxen\|Nitrites\|ochratoxin A\|Oxygen\|Ozone\|Penicillamine\|Pesticides\|Plant Extracts\|Prednisolone\|Reactive Oxygen Species\|Resveratrol\|Salicylates\|Sulindac\|Tobacco Smoke Pollution\|Tretinoin\|triptolide\|Vorinostat; Inference Score=74.98; Reference Count=385	details
DDIT3	gene	CTD	Gene Symbol=DDIT3; Gene ID=1649; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Azathioprine\|Chloroquine\|Curcumin\|Cyclophosphamide\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|Dinoprostone\|entinostat\|glyphosate\|Gold\|GW 506033X\|Indomethacin\|Leflunomide\|Methotrexate\|Minocycline\|Nabumetone\|ochratoxin A\|Oxygen\|Ozone\|Penicillamine\|Piroxicam\|Plant Extracts\|Reactive Oxygen Species\|Resveratrol\|Sulfasalazine\|Sulindac\|Tacrolimus\|Thalidomide\|thymoquinone\|Tobacco Smoke Pollution\|Tretinoin\|triptolide; Inference Score=73.46; Reference Count=419	details
BAX	gene	CTD	Gene Symbol=BAX; Gene ID=581; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Angiotensin-Converting Enzyme Inhibitors\|Arsenic Trioxide\|Aspartame\|Aspirin\|Auranofin\|Chlorambucil\|Chloroquine\|chloroquine diphosphate\|Curcumin\|Cyclophosphamide\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|Dinoprostone\|Edaravone\|Enalapril\|entinostat\|Freund's Adjuvant\|glyphosate\|Gold\|Gold Compounds\|GW 506033X\|Hydroxychloroquine\|Indomethacin\|mancozeb\|Maneb\|Meloxicam\|Methotrexate\|Methylprednisolone\|Minocycline\|Misoprostol\|ochratoxin A\|Organogold Compounds\|Oxygen\|Ozone\|Plant Extracts\|Quinacrine\|Reactive Oxygen Species\|Resveratrol\|Sulfasalazine\|Sulindac\|Tacrolimus\|Thalidomide\|thymoquinone\|Tobacco Smoke Pollution\|Tretinoin\|triptolide\|Vorinostat; Inference Score=73.42; Reference Count=275	details
TGFB1	gene	CTD	Gene Symbol=TGFB1; Gene ID=7040; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Angiotensin-Converting Enzyme Inhibitors\|Arsenic Trioxide\|Aspirin\|Aurothioglucose\|Azathioprine\|chloroquine diphosphate\|Curcumin\|Cyclophosphamide\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Dinoprostone\|Edaravone\|Enalapril\|Fenoprofen\|Freund's Adjuvant\|glyphosate\|Gold\|Hydrocortisone\|Indomethacin\|Maneb\|Methotrexate\|Methylprednisolone\|Minocycline\|Naproxen\|ochratoxin A\|Oxygen\|Ozone\|Plant Extracts\|Prednisolone\|Prednisone\|Reactive Oxygen Species\|Resveratrol\|Sulindac\|Tacrolimus\|tamibarotene\|Thalidomide\|thymoquinone\|Tobacco Smoke Pollution\|tofacitinib\|Tretinoin; Inference Score=73.35; Reference Count=245	details
GSK3B	gene	CTD	Gene Symbol=GSK3B; Gene ID=2932; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Curcumin\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|Dinoprostone\|Enalapril\|entinostat\|Famotidine\|GW 506033X\|Indomethacin\|mancozeb\|Maneb\|Methotrexate\|Minocycline\|Naproxen\|ochratoxin A\|Oxygen\|Plant Extracts\|Quinacrine\|Resveratrol\|Sulfasalazine\|Sulindac\|Tacrolimus\|tamibarotene\|Thalidomide\|thymoquinone\|Tobacco Smoke Pollution\|Tretinoin\|triptolide; Inference Score=70.66; Reference Count=208	details
IL2	gene	CTD	Gene Symbol=IL2; Gene ID=3558; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Angiotensin-Converting Enzyme Inhibitors\|Arsenic Trioxide\|Aspirin\|Chloroquine\|Curcumin\|Cyclophosphamide\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|Dinoprostone\|Famotidine\|Freund's Adjuvant\|Glucocorticoids\|Hydrocortisone\|Indomethacin\|Levamisole\|mancozeb\|Methotrexate\|Minocycline\|Naproxen\|ochratoxin A\|Ozone\|Plant Extracts\|Prednisolone\|Reactive Oxygen Species\|Resveratrol\|Sulfasalazine\|Tacrolimus\|Thalidomide\|tofacitinib\|Tretinoin; Inference Score=70.4; Reference Count=250	details
BCL2	gene	CTD	Gene Symbol=BCL2; Gene ID=596; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Angiotensin-Converting Enzyme Inhibitors\|Arsenic Trioxide\|Aspartame\|Aspirin\|Auranofin\|Chlorambucil\|Chloroquine\|chloroquine diphosphate\|Curcumin\|Cyclophosphamide\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|Dinoprostone\|Edaravone\|Enalapril\|entinostat\|Freund's Adjuvant\|Glucocorticoids\|glyphosate\|Gold\|Gold Compounds\|Indomethacin\|Levamisole\|mancozeb\|Maneb\|Methotrexate\|Methylprednisolone\|Minocycline\|Nabumetone\|ochratoxin A\|Oxygen\|Ozone\|Penicillamine\|Plant Extracts\|Reactive Oxygen Species\|Resveratrol\|Sulfasalazine\|Sulindac\|Tacrolimus\|tamibarotene\|Thalidomide\|thymoquinone\|Tobacco Smoke Pollution\|Tretinoin\|triptolide\|Vorinostat; Inference Score=67.13; Reference Count=432	details
TIMP1	gene	CTD	Gene Symbol=TIMP1; Gene ID=7076; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Aurothioglucose\|Azathioprine\|Chloroquine\|Curcumin\|Cyclophosphamide\|Cyclosporine\|Dexamethasone\|Diclofenac\|Dinoprostone\|Edaravone\|Flurbiprofen\|Indomethacin\|Naproxen\|ochratoxin A\|Oxygen\|Ozone\|Plant Extracts\|Prednisolone\|Resveratrol\|Sulfasalazine\|Sulindac\|Tacrolimus\|tamibarotene\|Thalidomide\|thymoquinone\|Tobacco Smoke Pollution\|Tretinoin; Inference Score=67.09; Reference Count=151	details
NFKB1	gene	CTD	Gene Symbol=NFKB1; Gene ID=4790; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Chloroquine\|Curcumin\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|Dinoprostone\|Enalapril\|Flurbiprofen\|glyphosate\|Gold Compounds\|GW 506033X\|Indomethacin\|Maneb\|Methotrexate\|Methylprednisolone\|Naproxen\|Oxygen\|Ozone\|Phenylbutazone\|Plant Extracts\|Resveratrol\|Salicylates\|Sulfasalazine\|Sulindac\|Tacrolimus\|Thalidomide\|Tobacco Smoke Pollution\|Tretinoin\|Vorinostat; Inference Score=66.54; Reference Count=240	details
TNFRSF1A	gene	CTD	Gene Symbol=TNFRSF1A; Gene ID=7132; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Azathioprine\|Chloroquine\|Curcumin\|Cyclosporine\|Dexamethasone\|Diclofenac\|Dinoprostone\|glyphosate\|Gold\|Indomethacin\|Leflunomide\|Methotrexate\|ochratoxin A\|Oxygen\|Ozone\|Pesticides\|Plant Extracts\|Resveratrol\|Thalidomide\|Tobacco Smoke Pollution\|Tretinoin\|valdecoxib\|Vorinostat; Inference Score=66.35; Reference Count=227	details