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rs2476601 |
SNP |
PedAM |
snpId=rs2476601; pubmedId=23637320; geneId=26191; geneSymbol=PTPN22; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Metaanalysis of the association of smoking and PTPN22 R620W genotype on autoantibody status and radiological erosions in rheumatoid arthritis.; score=0.524345611; Year=2014; geneSymbol_dbSNP=PTPN22;AP4B1-AS1; CHROMOSOME=1; POS=113834946; REF=A; ALT=G |
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rs2476601 |
SNP |
PedAM |
snpId=rs2476601; pubmedId=20975833; geneId=26191; geneSymbol=PTPN22; diseaseId=umls:C0003873; sourceId=BeFree; sentence=The PTPN22 locus and rheumatoid arthritis: no evidence for an effect on risk independent of Arg620Trp.; score=0.524345611; Year=2010; geneSymbol_dbSNP=PTPN22;AP4B1-AS1; CHROMOSOME=1; POS=113834946; REF=A; ALT=G |
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rs2476601 |
SNP |
PedAM |
snpId=rs2476601; pubmedId=20707220; geneId=1191; geneSymbol=CLU; diseaseId=umls:C0003873; sourceId=BeFree; sentence=To investigate a possible association between functional polymorphisms of the protein tyrosine phosphatase nonreceptor type 22 (PTPN22-R620W) and receptors for the Fc fragment of IgG (FcgRIIa-H131R, FcgRIIIa-F158V FcgRIIIb-NA1/NA2), and rheumatoid arthritis (RA), 133 Tunisian patients with RA and 100 controls were genotyped.; score=0.00408156; Year=2009; geneSymbol_dbSNP=PTPN22;AP4B1-AS1; CHROMOSOME=1; POS=113834946; REF=A; ALT=G |
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rs2476601 |
SNP |
PedAM |
snpId=rs2476601; pubmedId=21965649; geneId=26191; geneSymbol=PTPN22; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Evidence for PTPN22 R620W polymorphism as the sole common risk variant for rheumatoid arthritis in the 1p13.2 region.; score=0.524345611; Year=2011; geneSymbol_dbSNP=PTPN22;AP4B1-AS1; CHROMOSOME=1; POS=113834946; REF=A; ALT=G |
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rs2476601 |
SNP |
PedAM |
snpId=rs2476601; pubmedId=23350658; geneId=26191; geneSymbol=PTPN22; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Association of PTPN22 rs2476601 and EGFR rs17337023 Gene polymorphisms and rheumatoid arthritis in Zahedan, Southeast Iran.; score=0.524345611; Year=2012; geneSymbol_dbSNP=PTPN22;AP4B1-AS1; CHROMOSOME=1; POS=113834946; REF=A; ALT=G |
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rs2476601 |
SNP |
PedAM |
snpId=rs2476601; pubmedId=18156150; geneId=3123; geneSymbol=HLA-DRB1; diseaseId=umls:C0003873; sourceId=BeFree; sentence=To analyse the relationship between the presence of auto-antibodies [rheumatoid factor (RF) and anti-cyclic citrullinated peptide (anti-CCP)], HLA-DRB1 alleles and PTPN22 1858 C/T polymorphism and test the value of their combination as susceptibility markers for rheumatoid arthritis (RA).; score=0.36; Year=2008; geneSymbol_dbSNP=PTPN22;AP4B1-AS1; CHROMOSOME=1; POS=113834946; REF=A; ALT=G |
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rs2476601 |
SNP |
PedAM |
snpId=rs2476601; pubmedId=18305142; geneId=52; geneSymbol=ACP1; diseaseId=umls:C0003873; sourceId=BeFree; sentence=The disease association of the common 1858C>T Arg620Trp (rs2476601) nonsynonymous single nucleotide polymorphism (SNP) of protein tyrosine phosphatase; nonreceptor type 22 (PTPN22) on chromosome 1p13 has been confirmed in type 1 diabetes and also in other autoimmune diseases, including rheumatoid arthritis and Graves' disease.; score=0.007871814; Year=2008; geneSymbol_dbSNP=PTPN22;AP4B1-AS1; CHROMOSOME=1; POS=113834946; REF=A; ALT=G |
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rs2476601 |
SNP |
PedAM |
snpId=rs2476601; pubmedId=17170052; geneId=26191; geneSymbol=PTPN22; diseaseId=umls:C0003873; sourceId=BeFree; sentence=In contrast with a study of American patients with RA no evidence of association with PTPN22 independent of the well-characterised R620W variant was found, suggesting that in these patients this variant alone explains the association with the PTPN22 gene.; score=0.524345611; Year=2007; geneSymbol_dbSNP=PTPN22;AP4B1-AS1; CHROMOSOME=1; POS=113834946; REF=A; ALT=G |
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rs2476601 |
SNP |
PedAM |
snpId=rs2476601; pubmedId=20498205; geneId=1493; geneSymbol=CTLA4; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Eight markers (ie, rs1160542 (AFF3), rs1678542 (KIF5A), rs2476601 (PTPN22), rs3087243 (CTLA4), rs4810485 (CD40), rs5029937 (6q23), rs10760130 (TRAF1/C5) and rs7574865 (STAT4)) were significantly associated with RA by meta-analysis.; score=0.345272224; Year=2010; geneSymbol_dbSNP=PTPN22;AP4B1-AS1; CHROMOSOME=1; POS=113834946; REF=A; ALT=G |
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rs2476601 |
SNP |
PedAM |
snpId=rs2476601; pubmedId=16462519; geneId=26191; geneSymbol=PTPN22; diseaseId=umls:C0003873; sourceId=BeFree; sentence=PTPN22 has emerged strongly as a genuine rheumatoid arthritis susceptibility gene with replications of the association to the R620W single nucleotide polymorphism.; score=0.524345611; Year=2006; geneSymbol_dbSNP=PTPN22;AP4B1-AS1; CHROMOSOME=1; POS=113834946; REF=A; ALT=G |
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rs2476601 |
SNP |
PedAM |
snpId=rs2476601; pubmedId=21706348; geneId=26191; geneSymbol=PTPN22; diseaseId=umls:C0003873; sourceId=BeFree; sentence=The association between the PTPN22 C1858T polymorphism and rheumatoid arthritis: a meta-analysis update.; score=0.524345611; Year=2012; geneSymbol_dbSNP=PTPN22;AP4B1-AS1; CHROMOSOME=1; POS=113834946; REF=A; ALT=G |
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rs2476601 |
SNP |
PedAM |
snpId=rs2476601; pubmedId=23450725; geneId=6775; geneSymbol=STAT4; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Childhood-onset RA was associated with TNFAIP3 rs10499194 (OR 0.60 [95% confidence interval 0.44-0.83]), PTPN22 rs2476601 (OR 1.61 [95% confidence interval 1.11-2.31]), and STAT4 rs7574865 (OR 1.41 [95% confidence interval 1.06-1.87]) variants.; score=0.316739695; Year=2013; geneSymbol_dbSNP=PTPN22;AP4B1-AS1; CHROMOSOME=1; POS=113834946; REF=A; ALT=G |
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rs2476601 |
SNP |
PedAM |
snpId=rs2476601; pubmedId=17148556; geneId=26191; geneSymbol=PTPN22; diseaseId=umls:C0003873; sourceId=BeFree; sentence=A recent study reported associations of a series of single nucleotide polymorphisms (SNPs) within PTPN22, including rs2476601, with rheumatoid arthritis.; score=0.524345611; Year=2007; geneSymbol_dbSNP=PTPN22;AP4B1-AS1; CHROMOSOME=1; POS=113834946; REF=A; ALT=G |
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rs2476601 |
SNP |
PedAM |
snpId=rs2476601; pubmedId=23370857; geneId=52; geneSymbol=ACP1; diseaseId=umls:C0003873; sourceId=BeFree; sentence=The aim of this study was to determine whether the protein tyrosine phosphatase nonreceptor 22 (PTPN22) C1858T polymorphism confers susceptibility to rheumatoid arthritis (RA) in populations with different ethnicities.; score=0.007871814; Year=2013; geneSymbol_dbSNP=PTPN22;AP4B1-AS1; CHROMOSOME=1; POS=113834946; REF=A; ALT=G |
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rs2476601 |
SNP |
PedAM |
snpId=rs2476601; pubmedId=19343596; geneId=26191; geneSymbol=PTPN22; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Our data suggest that the PTPN22 C1858T single nucleotide polymorphism has no or minor effect on RA and AITDs susceptibility in the Tunisian population.; score=0.524345611; Year=2009; geneSymbol_dbSNP=PTPN22;AP4B1-AS1; CHROMOSOME=1; POS=113834946; REF=A; ALT=G |
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rs2476601 |
SNP |
PedAM |
snpId=rs2476601; pubmedId=15004560; geneId=26191; geneSymbol=PTPN22; diseaseId=umls:C0003873; sourceId=UNIPROT; sentence=A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes.; score=0.524345611; Year=2004; geneSymbol_dbSNP=PTPN22;AP4B1-AS1; CHROMOSOME=1; POS=113834946; REF=A; ALT=G |
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rs2476601 |
SNP |
PedAM |
snpId=rs2476601; pubmedId=20707220; geneId=52; geneSymbol=ACP1; diseaseId=umls:C0003873; sourceId=BeFree; sentence=To investigate a possible association between functional polymorphisms of the protein tyrosine phosphatase nonreceptor type 22 (PTPN22-R620W) and receptors for the Fc fragment of IgG (FcgRIIa-H131R, FcgRIIIa-F158V FcgRIIIb-NA1/NA2), and rheumatoid arthritis (RA), 133 Tunisian patients with RA and 100 controls were genotyped.; score=0.007871814; Year=2009; geneSymbol_dbSNP=PTPN22;AP4B1-AS1; CHROMOSOME=1; POS=113834946; REF=A; ALT=G |
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rs2476601 |
SNP |
PedAM |
snpId=rs2476601; pubmedId=22937072; geneId=3123; geneSymbol=HLA-DRB1; diseaseId=umls:C0003873; sourceId=BeFree; sentence=The number of copies of the HLA-DRB1 shared epitope, and the minor alleles of the STAT4 rs7574865 and the PTPN22 rs2476601 polymorphisms have all been linked with an increased risk of developing rheumatoid arthritis.; score=0.36; Year=2012; geneSymbol_dbSNP=PTPN22;AP4B1-AS1; CHROMOSOME=1; POS=113834946; REF=A; ALT=G |
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rs2476601 |
SNP |
PedAM |
snpId=rs2476601; pubmedId=23350658; geneId=1956; geneSymbol=EGFR; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Association of PTPN22 rs2476601 and EGFR rs17337023 Gene polymorphisms and rheumatoid arthritis in Zahedan, Southeast Iran.; score=0.001628651; Year=2012; geneSymbol_dbSNP=PTPN22;AP4B1-AS1; CHROMOSOME=1; POS=113834946; REF=A; ALT=G |
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rs2476601 |
SNP |
PedAM |
snpId=rs2476601; pubmedId=23370857; geneId=26191; geneSymbol=PTPN22; diseaseId=umls:C0003873; sourceId=BeFree; sentence=The PTPN22 C1858T polymorphism and rheumatoid arthritis: a meta-analysis.; score=0.524345611; Year=2013; geneSymbol_dbSNP=PTPN22;AP4B1-AS1; CHROMOSOME=1; POS=113834946; REF=A; ALT=G |
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