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rs1800896 |
SNP |
PedAM |
snpId=rs1800896; pubmedId=25566937; geneId=3569; geneSymbol=IL6; diseaseId=umls:C0003873; sourceId=BeFree; sentence=No associations were found for rs1800795 (IL-6), rs1800896 (IL-10) and rs7528684 (FCRL3) in the total RA-population and after stratification for ACPA.; score=0.212623944; Year=2014; geneSymbol_dbSNP=IL10; CHROMOSOME=1; POS=206773552; REF=T; ALT=C |
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rs1800896 |
SNP |
PedAM |
snpId=rs1800896; pubmedId=25566937; geneId=3586; geneSymbol=IL10; diseaseId=umls:C0003873; sourceId=BeFree; sentence=No associations were found for rs1800795 (IL-6), rs1800896 (IL-10) and rs7528684 (FCRL3) in the total RA-population and after stratification for ACPA.; score=0.203492066; Year=2014; geneSymbol_dbSNP=IL10; CHROMOSOME=1; POS=206773552; REF=T; ALT=C |
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rs1801131 |
SNP |
PedAM |
snpId=rs1801131; pubmedId=22927710; geneId=1234; geneSymbol=CCR5; diseaseId=umls:C0003873; sourceId=BeFree; sentence=In this regard, besides a strong association between the HLA-DRB104 shared epitope alleles and both endothelial dysfunction, an early step in the atherosclerotic process, and clinically evident CV disease, other polymorphisms belonging to genes implicated in inflammatory and metabolic pathways, located inside and outside the HLA region, such as the 308 variant (G > A, rs1800629) of the TNFA locus, the rs1801131 polymorphism (A > C; position + 1298) of the MTHFR locus, or a deletion of 32 base pairs on the CCR5 gene, seem to be associated with the risk of CV disease in patients with RA.; score=0.031985329; Year=2012; geneSymbol_dbSNP=MTHFR; CHROMOSOME=1; POS=11794419; REF=T; ALT=G |
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rs1801131 |
SNP |
PedAM |
snpId=rs1801131; pubmedId=22927710; geneId=3123; geneSymbol=HLA-DRB1; diseaseId=umls:C0003873; sourceId=BeFree; sentence=In this regard, besides a strong association between the HLA-DRB104 shared epitope alleles and both endothelial dysfunction, an early step in the atherosclerotic process, and clinically evident CV disease, other polymorphisms belonging to genes implicated in inflammatory and metabolic pathways, located inside and outside the HLA region, such as the 308 variant (G > A, rs1800629) of the TNFA locus, the rs1801131 polymorphism (A > C; position + 1298) of the MTHFR locus, or a deletion of 32 base pairs on the CCR5 gene, seem to be associated with the risk of CV disease in patients with RA.; score=0.36; Year=2012; geneSymbol_dbSNP=MTHFR; CHROMOSOME=1; POS=11794419; REF=T; ALT=G |
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rs1801131 |
SNP |
PedAM |
snpId=rs1801131; pubmedId=22927710; geneId=4524; geneSymbol=MTHFR; diseaseId=umls:C0003873; sourceId=BeFree; sentence=In this regard, besides a strong association between the HLA-DRB104 shared epitope alleles and both endothelial dysfunction, an early step in the atherosclerotic process, and clinically evident CV disease, other polymorphisms belonging to genes implicated in inflammatory and metabolic pathways, located inside and outside the HLA region, such as the 308 variant (G > A, rs1800629) of the TNFA locus, the rs1801131 polymorphism (A > C; position + 1298) of the MTHFR locus, or a deletion of 32 base pairs on the CCR5 gene, seem to be associated with the risk of CV disease in patients with RA.; score=0.20430773; Year=2012; geneSymbol_dbSNP=MTHFR; CHROMOSOME=1; POS=11794419; REF=T; ALT=G |
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rs1801131 |
SNP |
PedAM |
snpId=rs1801131; pubmedId=22927710; geneId=7124; geneSymbol=TNF; diseaseId=umls:C0003873; sourceId=BeFree; sentence=In this regard, besides a strong association between the HLA-DRB104 shared epitope alleles and both endothelial dysfunction, an early step in the atherosclerotic process, and clinically evident CV disease, other polymorphisms belonging to genes implicated in inflammatory and metabolic pathways, located inside and outside the HLA region, such as the 308 variant (G > A, rs1800629) of the TNFA locus, the rs1801131 polymorphism (A > C; position + 1298) of the MTHFR locus, or a deletion of 32 base pairs on the CCR5 gene, seem to be associated with the risk of CV disease in patients with RA.; score=0.425384406; Year=2012; geneSymbol_dbSNP=MTHFR; CHROMOSOME=1; POS=11794419; REF=T; ALT=G |
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rs1801274 |
SNP |
PedAM |
snpId=rs1801274; pubmedId=26314337; geneId=1191; geneSymbol=CLU; diseaseId=umls:C0003873; sourceId=BeFree; sentence=We conducted a meta-analysis on the association between FCGR2A H131R (rs1801274), FCGR3A F158V (rs396991), and FCGR3B NA1/NA2 polymorphisms and RA susceptibility.; score=0.00408156; Year=2015; geneSymbol_dbSNP=FCGR2A; CHROMOSOME=1; POS=161509955; REF=A; ALT=G |
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rs1801280 |
SNP |
PedAM |
snpId=rs1801280; pubmedId=17985847; geneId=6288; geneSymbol=SAA1; diseaseId=umls:C0003873; sourceId=BeFree; sentence=In this study, the six polymorphisms associated with rheumatoid arthritis (RA), N-acetyltransferase2 (NAT2) gene polymorphisms T341C, G590A, and G857A, methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms C677T and A1298C, and serum amyloid A1 (SAA1) gene promoter polymorphism C-13T were simultaneously detected by the electrochemical DNA chip and the loop-mediated isothermal amplification (LAMP) method, which is a novel technique for DNA amplification.; score=0.016425927; Year=2007; geneSymbol_dbSNP=NAT2; CHROMOSOME=8; POS=18400344; REF=T; ALT=C |
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rs1801280 |
SNP |
PedAM |
snpId=rs1801280; pubmedId=17985847; geneId=10; geneSymbol=NAT2; diseaseId=umls:C0003873; sourceId=BeFree; sentence=In this study, the six polymorphisms associated with rheumatoid arthritis (RA), N-acetyltransferase2 (NAT2) gene polymorphisms T341C, G590A, and G857A, methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms C677T and A1298C, and serum amyloid A1 (SAA1) gene promoter polymorphism C-13T were simultaneously detected by the electrochemical DNA chip and the loop-mediated isothermal amplification (LAMP) method, which is a novel technique for DNA amplification.; score=0.019726837; Year=2007; geneSymbol_dbSNP=NAT2; CHROMOSOME=8; POS=18400344; REF=T; ALT=C |
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rs1801280 |
SNP |
PedAM |
snpId=rs1801280; pubmedId=17985847; geneId=4524; geneSymbol=MTHFR; diseaseId=umls:C0003873; sourceId=BeFree; sentence=In this study, the six polymorphisms associated with rheumatoid arthritis (RA), N-acetyltransferase2 (NAT2) gene polymorphisms T341C, G590A, and G857A, methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms C677T and A1298C, and serum amyloid A1 (SAA1) gene promoter polymorphism C-13T were simultaneously detected by the electrochemical DNA chip and the loop-mediated isothermal amplification (LAMP) method, which is a novel technique for DNA amplification.; score=0.20430773; Year=2007; geneSymbol_dbSNP=NAT2; CHROMOSOME=8; POS=18400344; REF=T; ALT=C |
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rs1801282 |
SNP |
PedAM |
snpId=rs1801282; pubmedId=24697566; geneId=5468; geneSymbol=PPARG; diseaseId=umls:C0003873; sourceId=BeFree; sentence=The purpose of this study was to examine whether a Proline (Pro)-to-Alanine (Ala) exchange at codon 12 (Pro12Ala) polymorphism of the peroxisome proliferator-activated receptor-gamma (PPAR¦Ã) is associated with susceptibility to nonalcoholic fatty liver disease (NAFLD), rheumatoid arthritis (RA), and psoriatic arthritis (PsA).; score=0.006091273; Year=2014; geneSymbol_dbSNP=PPARG; CHROMOSOME=3; POS=12351626; REF=C; ALT=G |
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rs1801282 |
SNP |
PedAM |
snpId=rs1801282; pubmedId=23633103; geneId=5468; geneSymbol=PPARG; diseaseId=umls:C0003873; sourceId=BeFree; sentence=These observations suggest that Pro12Ala (rs1801282), a coding variant in the PPARG gene, is associated with Rheumatoid Arthritis in Pakistanis.; score=0.006091273; Year=2013; geneSymbol_dbSNP=PPARG; CHROMOSOME=3; POS=12351626; REF=C; ALT=G |
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rs1805010 |
SNP |
PedAM |
snpId=rs1805010; pubmedId=24782180; geneId=3566; geneSymbol=IL4R; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Increased Th17 cell frequency and poor clinical outcome in rheumatoid arthritis are associated with a genetic variant in the IL4R gene, rs1805010.; score=0.014364013; Year=2013; geneSymbol_dbSNP=IL4R; CHROMOSOME=16; POS=27344882; REF=A; ALT=C,G,T |
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rs1805010 |
SNP |
PedAM |
snpId=rs1805010; pubmedId=24782180; geneId=3565; geneSymbol=IL4; diseaseId=umls:C0003873; sourceId=BeFree; sentence=The data indicate that the rs1805010 minor allele contributes to increased Th17 cell frequency, enhanced clinical activity, and accelerated radiographic progression in RA by rendering CD4 T cells from RA patients insensitive to the attenuating effect of IL-4 on Th17 cell development.; score=0.033418483; Year=2013; geneSymbol_dbSNP=IL4R; CHROMOSOME=16; POS=27344882; REF=A; ALT=C,G,T |
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rs1805087 |
SNP |
PedAM |
snpId=rs1805087; pubmedId=17611986; geneId=4548; geneSymbol=MTR; diseaseId=umls:C0003873; sourceId=BeFree; sentence=To investigate the distribution of the A2756G polymorphism of the methionine synthase reductase (MTR) gene in patients with rheumatoid arthritis (RA) treated with methotrexate (MTX) compared with a healthy control group; and to examine the relationships among the A2756G polymorphism, plasma total homocysteine (tHcy), serum folate and vitamin B12 levels, disease activity, and MTX toxicity in patients with RA.; score=0.010011012; Year=2007; geneSymbol_dbSNP=MTR; CHROMOSOME=1; POS=236885200; REF=A; ALT=G |
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rs1805192 |
SNP |
PedAM |
snpId=rs1805192; pubmedId=23633103; geneId=5468; geneSymbol=PPARG; diseaseId=umls:C0003873; sourceId=BeFree; sentence=These observations suggest that Pro12Ala (rs1801282), a coding variant in the PPARG gene, is associated with Rheumatoid Arthritis in Pakistanis.; score=0.006091273; Year=2013; geneSymbol_dbSNP=PPARG; CHROMOSOME=3; POS=12379739; REF=C; ALT=G |
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rs1805192 |
SNP |
PedAM |
snpId=rs1805192; pubmedId=24697566; geneId=5468; geneSymbol=PPARG; diseaseId=umls:C0003873; sourceId=BeFree; sentence=The purpose of this study was to examine whether a Proline (Pro)-to-Alanine (Ala) exchange at codon 12 (Pro12Ala) polymorphism of the peroxisome proliferator-activated receptor-gamma (PPAR¦Ã) is associated with susceptibility to nonalcoholic fatty liver disease (NAFLD), rheumatoid arthritis (RA), and psoriatic arthritis (PsA).; score=0.006091273; Year=2014; geneSymbol_dbSNP=PPARG; CHROMOSOME=3; POS=12379739; REF=C; ALT=G |
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rs1809529 |
SNP |
PedAM |
snpId=rs1809529; pubmedId=22491018; geneId=6538; geneSymbol=SLC6A11; diseaseId=umls:C0003873; sourceId=GAD; sentence=[Genome-wide association analysis implicates the involvement of eight loci with response to tocilizumab for the treatment of rheumatoid arthritis.]; score=0.002367032; Year=2013; geneSymbol_dbSNP=SLC6A11; CHROMOSOME=3; POS=10835926; REF=C; ALT=T |
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rs1854853 |
SNP |
PedAM |
snpId=rs1854853; pubmedId=24782177; geneId=1235; geneSymbol=CCR6; diseaseId=umls:C0003873; sourceId=GWASCAT; sentence=Novel risk loci for rheumatoid arthritis in Han Chinese and congruence with risk variants in Europeans.; score=0.252539865; Year=2014; geneSymbol_dbSNP=CCR6;LOC105378122; CHROMOSOME=6; POS=167119574; REF=A; ALT=G |
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rs1858037 |
SNP |
PedAM |
snpId=rs1858037; pubmedId=24390342; geneId=200734; geneSymbol=SPRED2; diseaseId=umls:C0003873; sourceId=GWASCAT; sentence=Genetics of rheumatoid arthritis contributes to biology and drug discovery.; score=0.244734064; Year=2013; geneSymbol_dbSNP=SPRED2; CHROMOSOME=2; POS=65371166; REF=T; ALT=A |
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