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rs2004640 |
SNP |
PedAM |
snpId=rs2004640; pubmedId=18843785; geneId=5079; geneSymbol=PAX5; diseaseId=umls:C0003873; sourceId=BeFree; sentence=A combined analysis including all 3 independent cohorts from the previous study revealed an association of the rs2004640 with RA (pooled OR 1.21, 95% CI 1.07-1.38, pooled p = 0.0031 in dominant model).; score=0.003995683; Year=2008; geneSymbol_dbSNP=IRF5; CHROMOSOME=7; POS=128938247; REF=T; ALT=G |
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rs2004640 |
SNP |
PedAM |
snpId=rs2004640; pubmedId=23801380; geneId=3663; geneSymbol=IRF5; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Association of the IRF5 rs2004640 polymorphism with rheumatoid arthritis: a meta-analysis.; score=0.282449467; Year=2013; geneSymbol_dbSNP=IRF5; CHROMOSOME=7; POS=128938247; REF=T; ALT=G |
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rs2024301 |
SNP |
PedAM |
snpId=rs2024301; pubmedId=18480830; geneId=50856; geneSymbol=CLEC4A; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Cells with the RA-associated allele rs2024301 exhibit a significant increase in the expression of DCIR_v4.; score=0.00408156; Year=2008; geneSymbol_dbSNP=CLEC4A; CHROMOSOME=12; POS=8125585; REF=A; ALT=T |
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rs2027852 |
SNP |
PedAM |
snpId=rs2027852; pubmedId=22536334; geneId=3123; geneSymbol=HLA-DRB1; diseaseId=umls:C0003873; sourceId=BeFree; sentence=By analyzing homozygote intensities, an ROH that is anchored by the single nucleotide polymorphism rs2027852 and flanked by HLA-DRB6 and HLA-DRB1 was found associated with increased risk for RA.; score=0.36; Year=2012; geneSymbol_dbSNP=NA; CHROMOSOME=6; POS=32576575; REF=T; ALT=C |
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rs2041992 |
SNP |
PedAM |
snpId=rs2041992; pubmedId=25221852; geneId=3123; geneSymbol=HLA-DRB1; diseaseId=umls:C0003873; sourceId=BeFree; sentence=The association study in a discovery sample of 200 French trio families revealed a significant association with RA for one SNP, PGLYRP1-rs2041992 (p = 0.019); this association was stronger in trios where RA patients carried the HLA-DRB1 shared epitope (SE) (p = 0.003).; score=0.36; Year=2015; geneSymbol_dbSNP=PGLYRP1; CHROMOSOME=19; POS=46021213; REF=C; ALT=T |
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rs2041992 |
SNP |
PedAM |
snpId=rs2041992; pubmedId=25221852; geneId=8993; geneSymbol=PGLYRP1; diseaseId=umls:C0003873; sourceId=BeFree; sentence=The association study in a discovery sample of 200 French trio families revealed a significant association with RA for one SNP, PGLYRP1-rs2041992 (p = 0.019); this association was stronger in trios where RA patients carried the HLA-DRB1 shared epitope (SE) (p = 0.003).; score=0.000271442; Year=2015; geneSymbol_dbSNP=PGLYRP1; CHROMOSOME=19; POS=46021213; REF=C; ALT=T |
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rs2043211 |
SNP |
PedAM |
snpId=rs2043211; pubmedId=19319132; geneId=22900; geneSymbol=CARD8; diseaseId=umls:C0003873; sourceId=BeFree; sentence=The combination of the polymorphisms CARD8 (C10X)and NALP3 (Q705K) was recently shown to be associated with rheumatoid arthritis.Our aim was to investigate whether these combined polymorphisms play a role in the susceptibility to CD.; score=0.008815624; Year=2009; geneSymbol_dbSNP=CARD8; CHROMOSOME=19; POS=48234449; REF=A; ALT=T |
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rs2043211 |
SNP |
PedAM |
snpId=rs2043211; pubmedId=22128899; geneId=114548; geneSymbol=NLRP3; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Association study of CARD8 (p.C10X) and NLRP3 (p.Q705K) variants with rheumatoid arthritis in French and Tunisian populations.; score=0.010444275; Year=2012; geneSymbol_dbSNP=CARD8; CHROMOSOME=19; POS=48234449; REF=A; ALT=T |
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rs2043211 |
SNP |
PedAM |
snpId=rs2043211; pubmedId=23088220; geneId=49; geneSymbol=ACR; diseaseId=umls:C0003873; sourceId=BeFree; sentence=One thousand six hundred twenty-one patients fulfilling the 1987 ACR classification criteria for RA and 1300 matched controls, were genotyped for the CARD8 rs2043211 (30T>A, p.C10X) single-nucleotide polymorphism (SNP) using predesigned TaqMan SNP genotyping assay.; score=0.005700279; Year=2013; geneSymbol_dbSNP=CARD8; CHROMOSOME=19; POS=48234449; REF=A; ALT=T |
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rs2043211 |
SNP |
PedAM |
snpId=rs2043211; pubmedId=19443463; geneId=22900; geneSymbol=CARD8; diseaseId=umls:C0003873; sourceId=BeFree; sentence=CARD8 p.C10X polymorphism is associated with inflammatory activity in early rheumatoid arthritis.; score=0.008815624; Year=2010; geneSymbol_dbSNP=CARD8; CHROMOSOME=19; POS=48234449; REF=A; ALT=T |
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rs2043211 |
SNP |
PedAM |
snpId=rs2043211; pubmedId=22128899; geneId=22900; geneSymbol=CARD8; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Association study of CARD8 (p.C10X) and NLRP3 (p.Q705K) variants with rheumatoid arthritis in French and Tunisian populations.; score=0.008815624; Year=2012; geneSymbol_dbSNP=CARD8; CHROMOSOME=19; POS=48234449; REF=A; ALT=T |
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rs2043211 |
SNP |
PedAM |
snpId=rs2043211; pubmedId=19319132; geneId=114548; geneSymbol=NLRP3; diseaseId=umls:C0003873; sourceId=BeFree; sentence=The combination of the polymorphisms CARD8 (C10X)and NALP3 (Q705K) was recently shown to be associated with rheumatoid arthritis.Our aim was to investigate whether these combined polymorphisms play a role in the susceptibility to CD.; score=0.010444275; Year=2009; geneSymbol_dbSNP=CARD8; CHROMOSOME=19; POS=48234449; REF=A; ALT=T |
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rs2051179 |
SNP |
PedAM |
snpId=rs2051179; pubmedId=22449398; geneId=11126; geneSymbol=CD160; diseaseId=umls:C0003873; sourceId=BeFree; sentence=The results show that genes involved in functional gene modules, such as CD160 (rs744877) and RUNX1 (rs2051179), are especially relevant to RA, which is supported by previous reports.; score=0.001357209; Year=2012; geneSymbol_dbSNP=RUNX1; CHROMOSOME=21; POS=34954256; REF=A; ALT=T |
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rs2051179 |
SNP |
PedAM |
snpId=rs2051179; pubmedId=22449398; geneId=861; geneSymbol=RUNX1; diseaseId=umls:C0003873; sourceId=BeFree; sentence=The results show that genes involved in functional gene modules, such as CD160 (rs744877) and RUNX1 (rs2051179), are especially relevant to RA, which is supported by previous reports.; score=0.135621533; Year=2012; geneSymbol_dbSNP=RUNX1; CHROMOSOME=21; POS=34954256; REF=A; ALT=T |
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rs2062583 |
SNP |
PedAM |
snpId=rs2062583; pubmedId=21452313; geneId=50650; geneSymbol=ARHGEF3; diseaseId=umls:C0003873; sourceId=GAD; sentence=[Genetic risk for RA involves both population-specific loci as well as many shared genetic susceptibility loci in comparisons of Asian and European populations.]; score=0.002367032; Year=2011; geneSymbol_dbSNP=ARHGEF3; CHROMOSOME=3; POS=56932218; REF=G; ALT=T |
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rs2069763 |
SNP |
PedAM |
snpId=rs2069763; pubmedId=18650128; geneId=3558; geneSymbol=IL2; diseaseId=umls:C0003873; sourceId=BeFree; sentence=An IL-2 genetic G/T polymorphism (rs2069763) has been linked with multiple sclerosis and rheumatoid arthritis.; score=0.031889521; Year=2008; geneSymbol_dbSNP=IL2; CHROMOSOME=4; POS=122456327; REF=C; ALT=A |
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rs2071282 |
SNP |
PedAM |
snpId=rs2071282; pubmedId=23364395; geneId=129831; geneSymbol=RBM45; diseaseId=umls:C0003873; sourceId=BeFree; sentence=Although DRB1 and NOTCH4 were reported to be RA-susceptible, the three BTNL2 SNPs retained significant association with RA when evaluated by the logistic regression with the adjustment for RA-susceptible HLA-DRB1 alleles in Japanese or rs2071282-T in NOTCH4: P=0.0156 and P=0.00368, respectively.; score=0.049130979; Year=2013; geneSymbol_dbSNP=NOTCH4; CHROMOSOME=6; POS=32221166; REF=G; ALT=A |
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rs2072438 |
SNP |
PedAM |
snpId=rs2072438; pubmedId=24782177; geneId=26147; geneSymbol=PHF19; diseaseId=umls:C0003873; sourceId=GWASCAT; sentence=Novel risk loci for rheumatoid arthritis in Han Chinese and congruence with risk variants in Europeans.; score=0.122638474; Year=2014; geneSymbol_dbSNP=PHF19; CHROMOSOME=9; POS=120889023; REF=T; ALT=C |
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rs2072493 |
SNP |
PedAM |
snpId=rs2072493; pubmedId=21179534; geneId=7100; geneSymbol=TLR5; diseaseId=umls:C0003873; sourceId=BeFree; sentence=In the discovery phase of the study we found a significant association of SNPs rs2072493 in TLR5 and rs3853839 in TLR7 with RA disease susceptibility.; score=0.003181358; Year=2010; geneSymbol_dbSNP=TLR5; CHROMOSOME=1; POS=223111257; REF=T; ALT=C,A |
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rs2072493 |
SNP |
PedAM |
snpId=rs2072493; pubmedId=21179534; geneId=51284; geneSymbol=TLR7; diseaseId=umls:C0003873; sourceId=BeFree; sentence=In the discovery phase of the study we found a significant association of SNPs rs2072493 in TLR5 and rs3853839 in TLR7 with RA disease susceptibility.; score=0.002638474; Year=2010; geneSymbol_dbSNP=TLR5; CHROMOSOME=1; POS=223111257; REF=T; ALT=C,A |
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