RABC

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Biomarkers name	Biomarker Type	Source database	Information	Details
EDN1	gene	CTD	Gene Symbol=EDN1; Gene ID=1906; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Angiotensin-Converting Enzyme Inhibitors\|Arsenic Trioxide\|Cyclophosphamide\|Cyclosporine\|Dexamethasone\|Diclofenac\|Dinoprostone\|Enalapril\|entinostat\|Indomethacin\|Leflunomide\|Levamisole\|Methotrexate\|Methylprednisolone\|ochratoxin A\|Oxygen\|Ozone\|Plant Extracts\|Reactive Oxygen Species\|Resveratrol\|Tacrolimus\|tamibarotene\|Tobacco Smoke Pollution\|Tretinoin; Inference Score=44.47; Reference Count=189	details
S100A4	gene	CTD	Gene Symbol=S100A4; Gene ID=6275; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Arsenic Trioxide\|Aspirin\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|entinostat\|Methotrexate\|Oxygen\|Ozone\|Penicillamine\|Resveratrol\|tamibarotene\|Tobacco Smoke Pollution\|Tretinoin\|triptolide\|Vorinostat; Inference Score=44.46; Reference Count=320	details
UNG	gene	CTD	Gene Symbol=UNG; Gene ID=7374; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Aspirin\|Azathioprine\|Cyclophosphamide\|Cyclosporine\|Dexamethasone\|Diclofenac\|glyphosate\|Methotrexate\|Piroxicam\|Plant Extracts\|Resveratrol\|Sulindac\|Tretinoin\|Vorinostat; Inference Score=44.39; Reference Count=169	details
SFN	gene	CTD	Gene Symbol=SFN; Gene ID=2810; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Antirheumatic Agents\|Arsenic Trioxide\|Azathioprine\|Chlorambucil\|Cyclophosphamide\|Cyclosporine\|Diclofenac\|entinostat\|Methotrexate\|ochratoxin A\|Oxygen\|Ozone\|Tobacco Smoke Pollution\|Tretinoin\|triptolide\|Vorinostat; Inference Score=44.27; Reference Count=149	details
BRCA1	gene	CTD	Gene Symbol=BRCA1; Gene ID=672; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Arsenic Trioxide\|Aspirin\|Cyclosporine\|Diclofenac\|glyphosate\|Gold\|Methotrexate\|ochratoxin A\|Oxygen\|Ozone\|Plant Extracts\|Reactive Oxygen Species\|Resveratrol\|Sulindac\|tamibarotene\|Tretinoin\|Vorinostat; Inference Score=44.22; Reference Count=171	details
GSTM1	gene	CTD	Gene Symbol=GSTM1; Gene ID=2944; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Arsenic Trioxide\|Aspirin\|Azathioprine\|Chlorambucil\|Cyclophosphamide\|Cyclosporine\|Dexamethasone\|Diclofenac\|Indomethacin\|Mefenamic Acid\|Methotrexate\|ochratoxin A\|Oxygen\|Ozone\|Pesticides\|Plant Extracts\|Prednisone\|Resveratrol\|Solvents\|tamibarotene\|Tobacco Smoke Pollution\|Tretinoin; Inference Score=44.2; Reference Count=187	details
DUSP5	gene	CTD	Gene Symbol=DUSP5; Gene ID=1847; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Azathioprine\|Curcumin\|Cyclosporine\|Dexamethasone\|entinostat\|glyphosate\|Indomethacin\|Leflunomide\|Oxygen\|Ozone\|Tobacco Smoke Pollution\|Tretinoin\|valdecoxib; Inference Score=44.17; Reference Count=75	details
PHGDH	gene	CTD	Gene Symbol=PHGDH; Gene ID=26227; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Arsenic Trioxide\|Azathioprine\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Gold Sodium Thiomalate\|Indomethacin\|Methotrexate\|Methylprednisolone\|ochratoxin A\|Oxygen\|Ozone\|Piroxicam\|Prednisolone\|Tobacco Smoke Pollution\|valdecoxib; Inference Score=44.17; Reference Count=181	details
IGFBP1	gene	CTD	Gene Symbol=IGFBP1; Gene ID=3484; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Arsenic Trioxide\|Curcumin\|Cyclosporine\|Dexamethasone\|Diclofenac\|Enalapril\|Hydrocortisone\|Leflunomide\|Meloxicam\|ochratoxin A\|Oxygen\|Ozone\|Pesticides\|Plant Extracts\|Resveratrol\|Tacrolimus\|Tretinoin\|triptolide; Inference Score=44.14; Reference Count=43	details
LBP	gene	CTD	Gene Symbol=LBP; Gene ID=3929; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Antirheumatic Agents\|Curcumin\|Cyclosporine\|Dexamethasone\|Diclofenac\|Indomethacin\|Leflunomide\|Methotrexate\|Plant Extracts\|Resveratrol\|Sulindac\|Tacrolimus\|Tobacco Smoke Pollution\|Tretinoin\|valdecoxib; Inference Score=44.11; Reference Count=167	details
SHC1	gene	CTD	Gene Symbol=SHC1; Gene ID=6464; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Arsenic Trioxide\|Cyclosporine\|Dexamethasone\|Indomethacin\|ochratoxin A\|Oxygen\|Plant Extracts\|Reactive Oxygen Species\|Resveratrol\|Sulindac\|Tobacco Smoke Pollution\|Tretinoin\|triptolide\|valdecoxib\|Vorinostat; Inference Score=44.11; Reference Count=41	details
CFLAR	gene	CTD	Gene Symbol=CFLAR; Gene ID=8837; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Curcumin\|Dexamethasone\|Diclofenac\|entinostat\|glyphosate\|Hydroxychloroquine\|Indomethacin\|Methotrexate\|ochratoxin A\|Oxygen\|Plant Extracts\|Resveratrol\|Thalidomide\|Tretinoin\|Vorinostat; Inference Score=44.06; Reference Count=174	details
UGT2B7	gene	CTD	Gene Symbol=UGT2B7; Gene ID=7364; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|alclofenac\|Anti-Inflammatory Agents, Non-Steroidal\|benoxaprofen\|Cyclosporine\|deoxynivalenol\|Diclofenac\|Fenoprofen\|Flurbiprofen\|Indomethacin\|Ketoprofen\|Mefenamic Acid\|Naproxen\|pirprofen\|Plant Extracts\|Resveratrol\|Sulindac; Inference Score=44.05; Reference Count=64	details
BCL2L11	gene	CTD	Gene Symbol=BCL2L11; Gene ID=10018; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Curcumin\|Cyclophosphamide\|Dexamethasone\|Diclofenac\|entinostat\|Indomethacin\|Maneb\|ochratoxin A\|Oxygen\|Ozone\|Reactive Oxygen Species\|Resveratrol\|Tobacco Smoke Pollution\|Tretinoin\|Vorinostat; Inference Score=43.94; Reference Count=67	details
SIRT1	gene	CTD	Gene Symbol=SIRT1; Gene ID=23411; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Arsenic Trioxide\|Aspartame\|Aspirin\|Curcumin\|Cyclosporine\|Dexamethasone\|Dinoprostone\|Hydrocortisone\|Indomethacin\|mancozeb\|Maneb\|Methylprednisolone\|Nitrites\|Oxygen\|Plant Extracts\|Reactive Oxygen Species\|Resveratrol\|Sulindac\|thymoquinone\|Tobacco Smoke Pollution\|triptolide; Inference Score=43.91; Reference Count=62	details
NFKB2	gene	CTD	Gene Symbol=NFKB2; Gene ID=4791; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Antirheumatic Agents\|Arsenic Trioxide\|Curcumin\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|glyphosate\|Gold Compounds\|Indomethacin\|Methotrexate\|Ozone\|Plant Extracts\|Resveratrol\|Tacrolimus\|tofacitinib; Inference Score=43.84; Reference Count=164	details
PHLDA2	gene	CTD	Gene Symbol=PHLDA2; Gene ID=7262; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Antirheumatic Agents\|Arsenic Trioxide\|Azathioprine\|Cyclophosphamide\|Cyclosporine\|Dexamethasone\|entinostat\|Indomethacin\|Ozone\|Piroxicam\|Plant Extracts\|Tobacco Smoke Pollution\|Tretinoin\|valdecoxib\|Vorinostat; Inference Score=43.73; Reference Count=56	details
TLR3	gene	CTD	Gene Symbol=TLR3; Gene ID=7098; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Arsenic Trioxide\|Aspirin\|Chloroquine\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Freund's Adjuvant\|Gold Compounds\|Indomethacin\|Methotrexate\|Ozone\|Quinacrine\|Resveratrol\|Tretinoin; Inference Score=43.73; Reference Count=183	details
ITGB2	gene	CTD	Gene Symbol=ITGB2; Gene ID=3689; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|Indomethacin\|Methotrexate\|ochratoxin A\|Ozone\|Resveratrol\|Sulfasalazine\|tamibarotene\|Tobacco Smoke Pollution\|Tretinoin; Inference Score=43.7; Reference Count=185	details
LAMC1	gene	CTD	Gene Symbol=LAMC1; Gene ID=3915; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Cyclosporine\|Dexamethasone\|entinostat\|Indomethacin\|Methotrexate\|Oxygen\|Piroxicam\|Resveratrol\|tamibarotene\|Tobacco Smoke Pollution\|Tretinoin; Inference Score=43.67; Reference Count=149	details