RABC

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Biomarkers name	Biomarker Type	Source database	Information	Details
IGF1	gene	CTD	Gene Symbol=IGF1; Gene ID=3479; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Arsenic Trioxide\|Azathioprine\|Curcumin\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Enalapril\|Freund's Adjuvant\|glyphosate\|Gold\|Hydrocortisone\|Indomethacin\|Leflunomide\|Maneb\|ochratoxin A\|Oxygen\|Penicillamine\|Pesticides\|Plant Extracts\|Prednisolone\|Reactive Oxygen Species\|Resveratrol\|Tacrolimus\|Thalidomide\|Tobacco Smoke Pollution\|Tretinoin; Inference Score=48.96; Reference Count=249	details
PLPP3	gene	CTD	Gene Symbol=PLPP3; Gene ID=8613; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Arsenic Trioxide\|Azathioprine\|chloroquine diphosphate\|Cyclosporine\|Dexamethasone\|entinostat\|Gold Sodium Thiomalate\|Indomethacin\|Methotrexate\|Methylprednisolone\|Oxygen\|Piroxicam\|Prednisolone\|Tobacco Smoke Pollution\|Tretinoin\|triptolide\|valdecoxib; Inference Score=48.83; Reference Count=186	details
GBP1	gene	CTD	Gene Symbol=GBP1; Gene ID=2633; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Antirheumatic Agents\|Azathioprine\|chloroquine diphosphate\|Cyclophosphamide\|Cyclosporine\|Dexamethasone\|Diclofenac\|Gold Sodium Thiomalate\|Indomethacin\|Methotrexate\|Methylprednisolone\|ochratoxin A\|Piroxicam\|Prednisolone\|Tacrolimus\|Tretinoin; Inference Score=48.77; Reference Count=195	details
HSPB1	gene	CTD	Gene Symbol=HSPB1; Gene ID=3315; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Arsenic Trioxide\|Aspirin\|Curcumin\|Cyclophosphamide\|Dexamethasone\|Diclofenac\|Gold\|Indomethacin\|Leflunomide\|Methotrexate\|ochratoxin A\|Oxygen\|Ozone\|Plant Extracts\|Reactive Oxygen Species\|Resveratrol\|Thalidomide\|Tobacco Smoke Pollution\|Tretinoin\|valdecoxib\|Vorinostat; Inference Score=48.63; Reference Count=197	details
PCK1	gene	CTD	Gene Symbol=PCK1; Gene ID=5105; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Arsenic Trioxide\|Azathioprine\|Curcumin\|Cyclosporine\|Dexamethasone\|Diclofenac\|Hydrocortisone\|Indomethacin\|Leflunomide\|Methotrexate\|ochratoxin A\|Oxygen\|Ozone\|Plant Extracts\|Prednisolone\|Resveratrol\|Tobacco Smoke Pollution\|Tretinoin\|triptolide\|valdecoxib; Inference Score=48.46; Reference Count=181	details
MAPK3	gene	CTD	Gene Symbol=MAPK3; Gene ID=5595; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antigens\|Arsenic Trioxide\|Aspartame\|Aspirin\|Azathioprine\|Chloroquine\|Curcumin\|Cyclophosphamide\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|Dinoprostone\|Famotidine\|Flurbiprofen\|glyphosate\|GW 506033X\|Hydrocortisone\|Indomethacin\|Leflunomide\|LY 117018\|mancozeb\|Maneb\|Methotrexate\|ochratoxin A\|Oxygen\|Ozone\|Plant Extracts\|Quinacrine\|Reactive Oxygen Species\|Resveratrol\|Sulindac\|tamibarotene\|Thalidomide\|thymoquinone\|Tobacco Smoke Pollution\|tofacitinib\|Tretinoin\|triptolide\|Vorinostat; Inference Score=48.42; Reference Count=234	details
SAT1	gene	CTD	Gene Symbol=SAT1; Gene ID=6303; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Cyclosporine\|Dexamethasone\|Diclofenac\|Indomethacin\|Leflunomide\|Methotrexate\|Oxygen\|Piroxicam\|Resveratrol\|Sulindac\|tamibarotene\|Thalidomide\|Tobacco Smoke Pollution\|Tretinoin\|Vorinostat; Inference Score=48.41; Reference Count=180	details
CLU	gene	CTD	Gene Symbol=CLU; Gene ID=1191; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Antirheumatic Agents\|Arsenic Trioxide\|Chloroquine\|Cyclosporine\|Dexamethasone\|Diclofenac\|Enalapril\|entinostat\|Levamisole\|Maneb\|ochratoxin A\|Oxygen\|Ozone\|Penicillamine\|Resveratrol\|Sulfasalazine\|Sulindac\|Tacrolimus\|Tobacco Smoke Pollution\|Tretinoin\|triptolide; Inference Score=48.39; Reference Count=266	details
BECN1	gene	CTD	Gene Symbol=BECN1; Gene ID=8678; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Antirheumatic Agents\|Arsenic Trioxide\|Chloroquine\|chloroquine diphosphate\|Cyclophosphamide\|Cyclosporine\|Dexamethasone\|Freund's Adjuvant\|glyphosate\|Levamisole\|Maneb\|Methotrexate\|ochratoxin A\|Oxygen\|Ozone\|Reactive Oxygen Species\|Resveratrol\|Thalidomide\|Tobacco Smoke Pollution\|Tretinoin\|triptolide\|Vorinostat; Inference Score=48.17; Reference Count=174	details
MAPK8	gene	CTD	Gene Symbol=MAPK8; Gene ID=5599; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Arsenic Trioxide\|Chloroquine\|Curcumin\|Cyclophosphamide\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|Dinoprostone\|Edaravone\|entinostat\|glyphosate\|GW 506033X\|Methotrexate\|Minocycline\|ochratoxin A\|Oxygen\|Ozone\|Plant Extracts\|Reactive Oxygen Species\|Resveratrol\|Sulindac\|Tacrolimus\|Tobacco Smoke Pollution\|tofacitinib\|Tretinoin\|Vorinostat; Inference Score=48; Reference Count=190	details
PER2	gene	CTD	Gene Symbol=PER2; Gene ID=8864; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Curcumin\|Cyclosporine\|Dexamethasone\|entinostat\|Freund's Adjuvant\|Indomethacin\|Leflunomide\|Methotrexate\|Ozone\|Prednisolone\|Thalidomide\|Tobacco Smoke Pollution\|Tretinoin\|valdecoxib\|Vorinostat; Inference Score=48; Reference Count=164	details
E2F3	gene	CTD	Gene Symbol=E2F3; Gene ID=1871; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Cyclophosphamide\|Cyclosporine\|glyphosate\|Indomethacin\|Methotrexate\|ochratoxin A\|Oxygen\|Ozone\|Pesticides\|Reactive Oxygen Species\|Resveratrol\|triptolide; Inference Score=47.91; Reference Count=150	details
IL15	gene	CTD	Gene Symbol=IL15; Gene ID=3600; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Antirheumatic Agents\|Arsenic Trioxide\|Chloroquine\|Cyclophosphamide\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Freund's Adjuvant\|glyphosate\|Levamisole\|Oxygen\|Penicillamine\|Tobacco Smoke Pollution\|tofacitinib\|Tretinoin\|Vorinostat; Inference Score=47.72; Reference Count=238	details
ATG5	gene	CTD	Gene Symbol=ATG5; Gene ID=9474; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Chloroquine\|Cyclophosphamide\|Cyclosporine\|Dexamethasone\|glyphosate\|Indomethacin\|Levamisole\|ochratoxin A\|Oxygen\|Ozone\|Resveratrol\|thymoquinone\|Tretinoin\|triptolide\|Vorinostat; Inference Score=47.69; Reference Count=77	details
SLC20A1	gene	CTD	Gene Symbol=SLC20A1; Gene ID=6574; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Azathioprine\|Curcumin\|Cyclosporine\|Dexamethasone\|glyphosate\|Indomethacin\|Leflunomide\|Methotrexate\|Oxygen\|Ozone\|Plant Extracts\|Resveratrol\|Tobacco Smoke Pollution\|Tretinoin; Inference Score=47.62; Reference Count=167	details
ATF4	gene	CTD	Gene Symbol=ATF4; Gene ID=468; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Chloroquine\|Cyclosporine\|Dexamethasone\|Diclofenac\|glyphosate\|Gold\|Leflunomide\|ochratoxin A\|Oxygen\|Piroxicam\|Reactive Oxygen Species\|Resveratrol\|Sulindac\|Tacrolimus\|thymoquinone\|Tobacco Smoke Pollution\|Tretinoin\|triptolide; Inference Score=47.53; Reference Count=102	details
CD74	gene	CTD	Gene Symbol=CD74; Gene ID=972; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Cyclophosphamide\|Cyclosporine\|Dexamethasone\|entinostat\|Hydroxychloroquine\|Methotrexate\|ochratoxin A\|Oxygen\|Resveratrol\|Sulfasalazine\|Tacrolimus\|tamibarotene\|Tobacco Smoke Pollution\|Vorinostat; Inference Score=47.51; Reference Count=177	details
EIF4EBP1	gene	CTD	Gene Symbol=EIF4EBP1; Gene ID=1978; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Arsenic Trioxide\|Aspirin\|Chloroquine\|Curcumin\|Cyclophosphamide\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Diclofenac\|entinostat\|Indomethacin\|ochratoxin A\|Oxygen\|Ozone\|Plant Extracts\|Resveratrol\|Tacrolimus\|Tobacco Smoke Pollution\|Tretinoin; Inference Score=47.47; Reference Count=87	details
IL3	gene	CTD	Gene Symbol=IL3; Gene ID=3562; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Adjuvants, Immunologic\|Air Pollutants\|Aspartame\|Chloroquine\|Cyclophosphamide\|Cyclosporine\|Dexamethasone\|entinostat\|Methotrexate\|Naproxen\|Oxygen\|Plant Extracts\|Resveratrol\|Tacrolimus\|Tretinoin; Inference Score=47.42; Reference Count=167	details
LY6E	gene	CTD	Gene Symbol=LY6E; Gene ID=4061; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Arsenic Trioxide\|Azathioprine\|Cyclosporine\|Dexamethasone\|Diclofenac\|Gold Sodium Thiomalate\|Methotrexate\|Methylprednisolone\|Piroxicam\|Plant Extracts\|Prednisolone\|tamibarotene\|Tobacco Smoke Pollution\|Tretinoin\|triptolide; Inference Score=47.42; Reference Count=174	details