RABC

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Biomarkers name	Biomarker Type	Source database	Information	Details
BIRC5	gene	CTD	Gene Symbol=BIRC5; Gene ID=332; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Arsenic Trioxide\|Aspirin\|Azathioprine\|Chlorambucil\|Chloroquine\|Curcumin\|Cyclosporine\|Dexamethasone\|Dinoprostone\|entinostat\|Flurbiprofen\|Indomethacin\|Leflunomide\|ochratoxin A\|Oxygen\|Ozone\|Piroxicam\|Plant Extracts\|Reactive Oxygen Species\|Resveratrol\|Sulindac\|Tacrolimus\|thymoquinone\|Tobacco Smoke Pollution\|Tretinoin\|Vorinostat; Inference Score=50.9; Reference Count=104	details
HSD11B2	gene	CTD	Gene Symbol=HSD11B2; Gene ID=3291; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Azathioprine\|Betamethasone\|Cyclosporine\|Dexamethasone\|Dinoprostone\|entinostat\|Flurbiprofen\|Glucocorticoids\|Hydrocortisone\|Indomethacin\|Leflunomide\|Maneb\|Meloxicam\|Oxygen\|Plant Extracts\|Prednisolone\|Prednisone\|Thalidomide\|Tobacco Smoke Pollution; Inference Score=50.66; Reference Count=75	details
VCL	gene	CTD	Gene Symbol=VCL; Gene ID=7414; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Aspirin\|Cyclosporine\|Dexamethasone\|Diclofenac\|entinostat\|Gold\|Hydroxychloroquine\|Indomethacin\|Leflunomide\|Methotrexate\|Oxygen\|Ozone\|Resveratrol\|Tobacco Smoke Pollution\|Tretinoin; Inference Score=50.53; Reference Count=193	details
IFIT3	gene	CTD	Gene Symbol=IFIT3; Gene ID=3437; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Arsenic Trioxide\|Azathioprine\|Cyclosporine\|Diclofenac\|Gold Sodium Thiomalate\|Hydroxychloroquine\|Methotrexate\|Methylprednisolone\|Ozone\|Plant Extracts\|Prednisolone\|Resveratrol\|tamibarotene\|Tobacco Smoke Pollution\|tofacitinib\|Tretinoin\|triptolide; Inference Score=50.39; Reference Count=190	details
MX1	gene	CTD	Gene Symbol=MX1; Gene ID=4599; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Arsenic Trioxide\|Aspirin\|Azathioprine\|Cyclosporine\|Diclofenac\|Gold Sodium Thiomalate\|Methotrexate\|Methylprednisolone\|Ozone\|Piroxicam\|Plant Extracts\|Prednisolone\|Tobacco Smoke Pollution\|tofacitinib\|triptolide\|Vorinostat; Inference Score=50.39; Reference Count=194	details
RSAD2	gene	CTD	Gene Symbol=RSAD2; Gene ID=91543; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Azathioprine\|chloroquine diphosphate\|Cyclosporine\|Diclofenac\|glyphosate\|Gold Sodium Thiomalate\|Hydroxychloroquine\|Meloxicam\|Methotrexate\|Methylprednisolone\|ochratoxin A\|Piroxicam\|Prednisolone\|Resveratrol\|Tobacco Smoke Pollution\|tofacitinib\|Tretinoin; Inference Score=50.39; Reference Count=193	details
HSPA5	gene	CTD	Gene Symbol=HSPA5; Gene ID=3309; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Arsenic Trioxide\|Aspirin\|Chloroquine\|Curcumin\|Cyclophosphamide\|Cyclosporine\|deoxynivalenol\|Diclofenac\|Edaravone\|glyphosate\|GW 506033X\|Indomethacin\|Maneb\|Minocycline\|ochratoxin A\|Oxygen\|Ozone\|Penicillamine\|Plant Extracts\|Resveratrol\|Tacrolimus\|thymoquinone\|Tobacco Smoke Pollution\|Tretinoin\|triptolide\|Vorinostat; Inference Score=50.23; Reference Count=266	details
BST2	gene	CTD	Gene Symbol=BST2; Gene ID=684; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Antirheumatic Agents\|Arsenic Trioxide\|Azathioprine\|chloroquine diphosphate\|Cyclosporine\|Gold Sodium Thiomalate\|Methotrexate\|Methylprednisolone\|Piroxicam\|Prednisolone\|Resveratrol\|tamibarotene\|Thalidomide\|Tobacco Smoke Pollution\|tofacitinib\|Tretinoin\|triptolide; Inference Score=50.08; Reference Count=181	details
IFI6	gene	CTD	Gene Symbol=IFI6; Gene ID=2537; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Arsenic Trioxide\|Azathioprine\|Cyclosporine\|Dexamethasone\|Diclofenac\|entinostat\|Gold Sodium Thiomalate\|Methotrexate\|Methylprednisolone\|ochratoxin A\|Piroxicam\|Prednisolone\|Resveratrol\|Tretinoin\|Vorinostat; Inference Score=50.05; Reference Count=175	details
CDK1	gene	CTD	Gene Symbol=CDK1; Gene ID=983; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Arsenic Trioxide\|Azathioprine\|Chlorambucil\|Curcumin\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|glyphosate\|Gold\|GW 506033X\|Leflunomide\|Methotrexate\|ochratoxin A\|Oxygen\|Ozone\|Piroxicam\|Plant Extracts\|Reactive Oxygen Species\|Resveratrol\|Sulindac\|Thalidomide\|Tobacco Smoke Pollution\|Tretinoin\|triptolide\|Vorinostat; Inference Score=50.02; Reference Count=176	details
ODC1	gene	CTD	Gene Symbol=ODC1; Gene ID=4953; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Arsenic Trioxide\|Aspirin\|Curcumin\|Cyclophosphamide\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Leflunomide\|mancozeb\|Methotrexate\|ochratoxin A\|Oxygen\|Ozone\|Pesticides\|Plant Extracts\|Reactive Oxygen Species\|Resveratrol\|Sulfasalazine\|tamibarotene\|Tobacco Smoke Pollution\|Tretinoin\|valdecoxib; Inference Score=49.86; Reference Count=181	details
CCNB1	gene	CTD	Gene Symbol=CCNB1; Gene ID=891; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Arsenic Trioxide\|Aspirin\|Azathioprine\|Curcumin\|Cyclosporine\|Dexamethasone\|Flurbiprofen\|Freund's Adjuvant\|glyphosate\|Indomethacin\|Leflunomide\|Methotrexate\|ochratoxin A\|Oxygen\|Ozone\|Piroxicam\|Plant Extracts\|Resveratrol\|Sulindac\|Thalidomide\|thymoquinone\|Tobacco Smoke Pollution\|Tretinoin\|triptolide\|Vorinostat; Inference Score=49.84; Reference Count=195	details
RB1	gene	CTD	Gene Symbol=RB1; Gene ID=5925; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Auranofin\|Curcumin\|Dexamethasone\|Diclofenac\|Glucocorticoids\|Indomethacin\|Levamisole\|Maneb\|Methotrexate\|ochratoxin A\|Oxygen\|Ozone\|Piroxicam\|Plant Extracts\|Prednisone\|Resveratrol\|Sulindac\|Tobacco Smoke Pollution\|Tretinoin\|valdecoxib\|Vorinostat; Inference Score=49.54; Reference Count=196	details
CCL4	gene	CTD	Gene Symbol=CCL4; Gene ID=6351; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Adjuvants, Immunologic\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Betamethasone\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Dinoprostone\|Hydrocortisone\|Indomethacin\|Methotrexate\|Minocycline\|Oxygen\|Ozone\|Penicillamine\|Prednisolone\|Resveratrol\|tamibarotene\|Tobacco Smoke Pollution\|Tretinoin; Inference Score=49.51; Reference Count=332	details
CXCL5	gene	CTD	Gene Symbol=CXCL5; Gene ID=6374; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Cyclophosphamide\|deoxynivalenol\|Dexamethasone\|entinostat\|GW 506033X\|Indomethacin\|Naproxen\|Oxygen\|Ozone\|Pesticides\|Plant Extracts\|Resveratrol\|Tobacco Smoke Pollution\|Vorinostat; Inference Score=49.5; Reference Count=64	details
MDM2	gene	CTD	Gene Symbol=MDM2; Gene ID=4193; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Arsenic Trioxide\|Aspartame\|Aspirin\|Chlorambucil\|Curcumin\|Cyclosporine\|deoxynivalenol\|Diclofenac\|Freund's Adjuvant\|glyphosate\|Indomethacin\|Leflunomide\|mancozeb\|Methotrexate\|ochratoxin A\|Oxygen\|Plant Extracts\|Reactive Oxygen Species\|Resveratrol\|thymoquinone\|Tobacco Smoke Pollution\|valdecoxib\|Vorinostat; Inference Score=49.4; Reference Count=179	details
JAK2	gene	CTD	Gene Symbol=JAK2; Gene ID=3717; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Auranofin\|baricitinib\|Curcumin\|Cyclosporine\|deoxynivalenol\|Dexamethasone\|Freund's Adjuvant\|Gold\|ochratoxin A\|Oxygen\|Ozone\|Plant Extracts\|Reactive Oxygen Species\|Resveratrol\|Sulfasalazine\|Tacrolimus\|tofacitinib; Inference Score=49.26; Reference Count=89	details
XIAP	gene	CTD	Gene Symbol=XIAP; Gene ID=331; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Arsenic Trioxide\|Aspirin\|Curcumin\|Cyclosporine\|Dexamethasone\|Diclofenac\|entinostat\|glyphosate\|Indomethacin\|Minocycline\|Ozone\|Plant Extracts\|Reactive Oxygen Species\|Resveratrol\|Sulindac\|Thalidomide\|thymoquinone\|Tretinoin\|triptolide\|valdecoxib\|Vorinostat; Inference Score=49.17; Reference Count=69	details
NQO1	gene	CTD	Gene Symbol=NQO1; Gene ID=1728; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Air Pollutants\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Azathioprine\|Curcumin\|Cyclophosphamide\|Cyclosporine\|Dexamethasone\|Diclofenac\|entinostat\|Flurbiprofen\|Freund's Adjuvant\|glyphosate\|Gold\|Hydrocortisone\|Leflunomide\|Maneb\|Mefenamic Acid\|Methotrexate\|ochratoxin A\|Oxygen\|Ozone\|Plant Extracts\|Resveratrol\|Sulfasalazine\|Sulindac\|Tobacco Smoke Pollution\|Tretinoin\|triptolide\|valdecoxib\|Vorinostat; Inference Score=49.11; Reference Count=222	details
CPT1A	gene	CTD	Gene Symbol=CPT1A; Gene ID=1374; Disease Name=Arthritis, Rheumatoid; Disease ID=MESH:D001172; Direct Evidence=NA; Inference Network=Acetaminophen\|Antirheumatic Agents\|Arsenic Trioxide\|Aspirin\|Curcumin\|Cyclosporine\|Dexamethasone\|Diclofenac\|entinostat\|Gold\|Hydrocortisone\|Indomethacin\|Leflunomide\|Methotrexate\|Oxygen\|Ozone\|Penicillamine\|Pesticides\|Plant Extracts\|Resveratrol\|Tobacco Smoke Pollution\|Tretinoin\|triptolide; Inference Score=49.04; Reference Count=350	details